id	category	name	description	provided_by	synonym	0000233	0000589	0100001	comment	consider	created_by	creation_date	default_namespace	deprecated	has_alternative_id	has_db_xref	has_o_b_o_format_version	has_o_b_o_namespace	is_class_level	is_metadata_tag	knowledge_source	license	logical_interpretation	object	predicate	relation	shorthand	subject	type	version
GO:0009590	biolink:NamedThing	detection of gravity	The series of events in which a gravitational stimulus is received and converted into a molecular signal.	got7fsn_ti	perception of gravity													biological_process											owl:Class	
GO:0009582	biolink:NamedThing	detection of abiotic stimulus	The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of abiotic stimulus													biological_process											owl:Class	
GO:0048282	biolink:NamedThing	determinate inflorescence morphogenesis	The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems.	got7fsn_ti														biological_process											owl:Class	
GO:0048281	biolink:NamedThing	inflorescence morphogenesis	The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers.	got7fsn_ti														biological_process											owl:Class	
GO:0007319	biolink:NamedThing	negative regulation of oskar mRNA translation	Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein.	got7fsn_ti	down-regulation of oskar mRNA translation|downregulation of oskar mRNA translation|down regulation of oskar mRNA translation|inhibition of oskar mRNA translation													biological_process											owl:Class	
GO:0046011	biolink:NamedThing	regulation of oskar mRNA translation	Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0043909	biolink:NamedThing	N-acetylcitrulline deacetylase activity	Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.	got7fsn_ti	acetylcitrulline deacetylase activity|N-acetyl-L-citrulline deacetylase activity											RHEA:61092		molecular_function											owl:Class	
GO:0016811	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.	got7fsn_ti												Reactome:R-HSA-9673054|Reactome:R-HSA-9673053|EC:3.5.1.-		molecular_function											owl:Class	
GO:0048523	biolink:NamedThing	negative regulation of cellular process	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	got7fsn_ti	inhibition of cellular process|down regulation of cellular process|negative regulation of cellular physiological process|down-regulation of cellular process|downregulation of cellular process										GO:0051243			biological_process											owl:Class	
GO:0050794	biolink:NamedThing	regulation of cellular process	Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	got7fsn_ti	regulation of cellular physiological process										GO:0051244			biological_process											owl:Class	
GO:0018647	biolink:NamedThing	phenanthrene 1,2-monooxygenase activity	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide.	got7fsn_ti												UM-BBD_enzymeID:e0333|EC:1.14.13.-		molecular_function											owl:Class	
GO:0016709	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.	got7fsn_ti	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen											Reactome:R-HSA-2162187|Reactome:R-HSA-2162194|EC:1.14.13.-		molecular_function											owl:Class	
GO:0071241	biolink:NamedThing	cellular response to inorganic substance	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.	got7fsn_ti							mah	2009-12-03T02:35:49Z						biological_process											owl:Class	
GO:0010035	biolink:NamedThing	response to inorganic substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0005723	biolink:NamedThing	alpha-heterochromatin	A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization.	got7fsn_ti														cellular_component											owl:Class	
GO:0005721	biolink:NamedThing	pericentric heterochromatin	Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.	got7fsn_ti	nuclear cluster|centromeric heterochromatin|nuclear centric heterochromatin|nuclear pericentric heterochromatin|centric heterochromatin										GO:0031618|GO:0002137			cellular_component											owl:Class	
GO:0046527	biolink:NamedThing	glucosyltransferase activity	Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0016758	biolink:NamedThing	hexosyltransferase activity	Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring hexosyl groups											EC:2.4.1.-		molecular_function											owl:Class	
GO:0019046	biolink:NamedThing	release from viral latency	The process by which a virus begins to replicate following a latency replication decision (switch).	got7fsn_ti											GO:0075717			biological_process											owl:Class	
GO:0016032	biolink:NamedThing	viral process	A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.	got7fsn_ti	viral infection|virulence|virus process				See also the biological process terms 'viral infectious cycle ; GO:0019058' and 'lysogeny ; GO:0030069'.						GO:0022415	Wikipedia:Viral_life_cycle		biological_process											owl:Class	
GO:0043545	biolink:NamedThing	molybdopterin cofactor metabolic process	The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.	got7fsn_ti	Moco metabolic process|Moco metabolism|molybdopterin cofactor metabolism													biological_process											owl:Class	
GO:0051189	biolink:NamedThing	prosthetic group metabolic process	The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.	got7fsn_ti	prosthetic group metabolism|coenzyme and prosthetic group metabolic process|coenzyme and prosthetic group metabolism													biological_process											owl:Class	
GO:0047187	biolink:NamedThing	deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity	Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate.	got7fsn_ti	deacetyl-citrate-(pro-3S)-lyase S-acetyltransferase activity|S-acetylphosphopantetheine:deacetyl-citrate-oxaloacetate-lyase((pro-3S)-CH2COO-rightacetate)S-acetyltransferase activity|deacetyl-citrate-(pro-3S)-lyase acetyltransferase activity|S-acetyl phosphopantetheine:deacetyl citrate lyase S-acetyltransferase activity											EC:2.3.1.49|MetaCyc:2.3.1.49-RXN|RHEA:20393		molecular_function											owl:Class	
GO:0140096	biolink:NamedThing	catalytic activity, acting on a protein	Catalytic activity that acts to modify a protein.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14225					pg	2017-09-14T10:32:59Z						molecular_function											owl:Class	
GO:0021915	biolink:NamedThing	neural tube development	The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.	got7fsn_ti														biological_process											owl:Class	
GO:0032502	biolink:NamedThing	developmental process	A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.	got7fsn_ti	development|single-organism developmental process						jl	2012-12-19T12:21:31Z			GO:0044767			biological_process											owl:Class	
GO:0031853	biolink:NamedThing	nociceptin receptor binding	Binding to a nociceptin receptor.	got7fsn_ti	nociceptin receptor ligand													molecular_function											owl:Class	
GO:0031628	biolink:NamedThing	opioid receptor binding	Binding to an opioid receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0042550	biolink:NamedThing	photosystem I stabilization	The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0042548	biolink:NamedThing	regulation of photosynthesis, light reaction	Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0072294	biolink:NamedThing	specification of metanephric connecting tubule identity	The process in which the connecting tubule of the metanephric nephron acquires its identity.	got7fsn_ti							mah	2010-04-09T04:00:31Z						biological_process											owl:Class	
GO:0072293	biolink:NamedThing	specification of metanephric nephron tubule identity	The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity.	got7fsn_ti							mah	2010-04-09T03:58:10Z						biological_process											owl:Class	
GO:0048511	biolink:NamedThing	rhythmic process	Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.	got7fsn_ti	rhythm													biological_process											owl:Class	
GO:0008150	biolink:NamedThing	biological_process	A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.	got7fsn_ti	physiological process|biological process|single organism process|single-organism process				Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.		jl	2012-09-19T15:05:24Z			GO:0000004|GO:0044699|GO:0007582	Wikipedia:Biological_process		biological_process											owl:Class	
GO:0062203	biolink:NamedThing	Viteagnusin D synthase activity	Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D.	got7fsn_ti							dph	2020-01-02T18:25:47Z				RHEA:62180		molecular_function											owl:Class	
GO:0016838	biolink:NamedThing	carbon-oxygen lyase activity, acting on phosphates	Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.	got7fsn_ti												EC:4.2.3.-		molecular_function											owl:Class	
GO:0120152	biolink:NamedThing	calcium-dependent outer dynein arm binding	Binding to an outer dynein arm in the presence of calcium.	got7fsn_ti							krc	2018-04-27T16:33:39Z						molecular_function											owl:Class	
GO:0048306	biolink:NamedThing	calcium-dependent protein binding	Binding to a protein or protein complex in the presence of calcium.	got7fsn_ti														molecular_function											owl:Class	
GO:0098039	biolink:NamedThing	replicative transposition, DNA-mediated	Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition.	got7fsn_ti	copy-and-paste transposition|transpositional DNA genome replication						bm	2012-07-20T16:52:02Z						biological_process											owl:Class	
GO:0006313	biolink:NamedThing	transposition, DNA-mediated	Any process involved in a type of transpositional recombination which occurs via a DNA intermediate.	got7fsn_ti	Class II transposition|Tc1/mariner transposition|Tc3 transposition|P-element transposition|P-element excision|DNA transposition										GO:0006317|GO:0006318			biological_process											owl:Class	
GO:0048920	biolink:NamedThing	posterior lateral line neuromast primordium migration	The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.	got7fsn_ti	PLL neuromast primordium migration													biological_process											owl:Class	
GO:0048883	biolink:NamedThing	neuromast primordium migration	The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.	got7fsn_ti	lateral line primordium migration													biological_process											owl:Class	
GO:0034070	biolink:NamedThing	aminoglycoside 1-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.	got7fsn_ti														molecular_function											owl:Class	
GO:0034069	biolink:NamedThing	aminoglycoside N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.	got7fsn_ti	kanamycin acetyltransferase activity													molecular_function											owl:Class	
GO:0061663	biolink:NamedThing	NEDD8 ligase activity	Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3						dph	2014-11-06T13:57:00Z						molecular_function											owl:Class	
GO:0019788	biolink:NamedThing	NEDD8 transferase activity	Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.	got7fsn_ti	RUB1 conjugating enzyme activity|NEDD8 conjugating enzyme activity|Hub1 conjugating enzyme activity										GO:0019945|GO:0042295|GO:0016976	Reactome:R-HSA-8956025|Reactome:R-HSA-8952618|Reactome:R-HSA-8951764|Reactome:R-HSA-8952638|Reactome:R-HSA-8951661|Reactome:R-HSA-8951648|Reactome:R-HSA-8952044		molecular_function											owl:Class	
GO:0106054	biolink:NamedThing	tRNA U34 thiol-transferase activity	Catalysis of the reaction: uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.	got7fsn_ti	tRNA-specific 2-thiouridylase|tRNA U34 2-thiouridylase						hjd	2017-09-05T19:10:12Z						molecular_function											owl:Class	
GO:0016783	biolink:NamedThing	sulfurtransferase activity	Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).	got7fsn_ti	sulphurtransferase activity|tRNA sulfurtransferase activity											Reactome:R-HSA-6782264|EC:2.8.1.-|Reactome:R-HSA-1614618|Reactome:R-HSA-947538		molecular_function											owl:Class	
GO:0021852	biolink:NamedThing	pyramidal neuron migration to cerebral cortex	The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex.	got7fsn_ti	projection neuron migration|pyramidal neuron migration	https://github.com/geneontology/go-ontology/issues/21476												biological_process											owl:Class	
GO:0001764	biolink:NamedThing	neuron migration	The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.	got7fsn_ti	neuron guidance|neuron chemotaxis|neuronal migration											Wikipedia:Neuron_migration|Wikipedia:Neural_development#Neuron_migration		biological_process											owl:Class	
GO:0044651	biolink:NamedThing	adhesion of symbiont to host epithelial cell	The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.	got7fsn_ti							jl	2012-07-12T12:47:09Z						biological_process											owl:Class	
GO:0044650	biolink:NamedThing	adhesion of symbiont to host cell	The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.	got7fsn_ti							jl	2012-07-12T12:42:14Z						biological_process											owl:Class	
GO:0003026	biolink:NamedThing	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control.	got7fsn_ti	aortic arch baroreceptor control of systemic arterial blood pressure													biological_process											owl:Class	
GO:0001976	biolink:NamedThing	nervous system process involved in regulation of systemic arterial blood pressure	The regulation of blood pressure mediated by detection of stimuli and a neurological response.	got7fsn_ti	blood pressure regulation by neurological process|neurological process involved in regulation of systemic arterial blood pressure|neurological system process involved in regulation of systemic arterial blood pressure|fast control of arterial pressure													biological_process											owl:Class	
GO:0051504	biolink:NamedThing	diterpene phytoalexin precursor biosynthetic process pathway	A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins.	got7fsn_ti	diterpene phytoalexin precursor synthesis pathway|diterpene phytoalexin precursor formation pathway|diterpene phytoalexin precursor anabolism pathway											MetaCyc:PWY-2981		biological_process											owl:Class	
GO:0046246	biolink:NamedThing	terpene biosynthetic process	The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units.	got7fsn_ti	terpene biosynthesis|terpene synthesis|terpene formation|terpene anabolism													biological_process											owl:Class	
GO:0018748	biolink:NamedThing	iprodione amidohydrolase activity	Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate.	got7fsn_ti												UM-BBD_reactionID:r0706		molecular_function											owl:Class	
GO:0098681	biolink:NamedThing	synaptic ribbon	A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles.  Synaptic ribbons may be plate like or spherical.	got7fsn_ti							dos	2017-02-05T15:59:43Z						cellular_component											owl:Class	
GO:0043232	biolink:NamedThing	intracellular non-membrane-bounded organelle	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.	got7fsn_ti	intracellular non-membrane-enclosed organelle													cellular_component											owl:Class	
GO:0005585	biolink:NamedThing	collagen type II trimer	A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils.	got7fsn_ti												Wikipedia:Collagen_type_II		cellular_component											owl:Class	
GO:0005583	biolink:NamedThing	fibrillar collagen trimer	Any triple helical collagen trimer that forms fibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0150017	biolink:NamedThing	basal proximal dendrite	Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma).	got7fsn_ti							bc	2017-12-21T12:17:00Z						cellular_component											owl:Class	
GO:0097441	biolink:NamedThing	basal dendrite	A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon.	got7fsn_ti	basilar dendrite						pr	2012-12-06T13:46:28Z				NIF_Subcellular:sao1079900774		cellular_component											owl:Class	
GO:0010461	biolink:NamedThing	light-activated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens in response to a light stimulus.	got7fsn_ti														molecular_function											owl:Class	
GO:0005216	biolink:NamedThing	ion channel activity	Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).	got7fsn_ti														molecular_function											owl:Class	
GO:0034319	biolink:NamedThing	alcohol O-butanoyltransferase activity	Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester.	got7fsn_ti														molecular_function											owl:Class	
GO:0034318	biolink:NamedThing	alcohol O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule.	got7fsn_ti	acyl-CoA:alcohol O-acyltransferase activity|acyl-CoA:ethanol O-acyltransferase|acyl-coenzymeA:alcohol O-acyltransferase activity|AEATase activity|alcohol acyltransferase activity|acyl-coenzymeA:ethanol O-acyltransferase activity													molecular_function											owl:Class	
GO:0007310	biolink:NamedThing	oocyte dorsal/ventral axis specification	The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte dorsal/ventral axis determination|oocyte dorsal-ventral axis specification|oocyte dorsoventral axis specification										GO:0008072|GO:0048123			biological_process											owl:Class	
GO:0007309	biolink:NamedThing	oocyte axis specification	The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte axis determination										GO:0048111			biological_process											owl:Class	
GO:0050267	biolink:NamedThing	rubber cis-polyprenylcistransferase activity	Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit.	got7fsn_ti	rubber transferase activity|rubber allyltransferase activity|poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase activity|cis-prenyl transferase activity|isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase activity|rubber polymerase activity|rubber prenyltransferase activity											RHEA:18801|EC:2.5.1.20|MetaCyc:2.5.1.20-RXN		molecular_function											owl:Class	
GO:0002094	biolink:NamedThing	polyprenyltransferase activity	Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).	got7fsn_ti														molecular_function											owl:Class	
GO:0035894	biolink:NamedThing	positive regulation of platelet aggregation in other organism	Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism.	got7fsn_ti	upregulation of platelet aggregation in other organism|up-regulation of platelet aggregation in other organism						bf	2011-06-15T02:28:46Z						biological_process											owl:Class	
GO:0035892	biolink:NamedThing	modulation of platelet aggregation in other organism	Any process in which an organism modulates the frequency, rate or extent of platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.	got7fsn_ti	regulation of platelet aggregation in other organism|modulation by organism of platelet aggregation in other organism						bf	2011-06-15T02:21:10Z						biological_process											owl:Class	
GO:0072010	biolink:NamedThing	glomerular epithelium development	The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	got7fsn_ti							mah	2010-01-25T02:02:14Z						biological_process											owl:Class	
GO:0072073	biolink:NamedThing	kidney epithelium development	The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	got7fsn_ti							mah	2010-01-25T04:37:42Z						biological_process											owl:Class	
GO:0051524	biolink:NamedThing	cell growth mode switching, bipolar to monopolar	The process in which a cell switches from bipolar cell growth to monopolar cell growth.	got7fsn_ti														biological_process											owl:Class	
GO:0061162	biolink:NamedThing	establishment of monopolar cell polarity	The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.	got7fsn_ti							dph	2010-06-23T09:30:59Z						biological_process											owl:Class	
GO:0018627	biolink:NamedThing	2-aminobenzenesulfonate 2,3-dioxygenase activity	Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.	got7fsn_ti	2-aminobenzenesulfonate dioxygenase activity|2-aminosulfobenzene 2,3-dioxygenase activity|2-aminobenzenesulphonate 2,3-dioxygenase activity|2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)|2-aminobenzenesulphonate dioxygenase activity										GO:0018605	KEGG_REACTION:R05156|EC:1.14.12.14|MetaCyc:2ASDOSALCAL-RXN|UM-BBD_reactionID:r0218|RHEA:23468		molecular_function											owl:Class	
GO:0016708	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.	got7fsn_ti	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor											EC:1.14.12.-		molecular_function											owl:Class	
GO:0120101	biolink:NamedThing	bacterial-type flagellum stator complex	A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species.	got7fsn_ti	bacterial-type flagellum torque generator complex|bacterial-type flagellum motor force generator complex						krc	2017-10-03T16:06:16Z						cellular_component											owl:Class	
GO:0005887	biolink:NamedThing	integral component of plasma membrane	The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to plasma membrane													cellular_component											owl:Class	
GO:0019156	biolink:NamedThing	isoamylase activity	Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins.	got7fsn_ti	debranching enzyme activity|glycogen alpha-1,6-glucanohydrolase activity											MetaCyc:RXN-12280|MetaCyc:3.2.1.68-RXN|EC:3.2.1.68|MetaCyc:RXN-14380		molecular_function											owl:Class	
GO:0004553	biolink:NamedThing	hydrolase activity, hydrolyzing O-glycosyl compounds	Catalysis of the hydrolysis of any O-glycosyl bond.	got7fsn_ti	O-glucosyl hydrolase activity										GO:0016800	Reactome:R-HSA-9661820|EC:3.2.1.-|Reactome:R-HSA-6786652|Reactome:R-HSA-5694563		molecular_function											owl:Class	
GO:0110148	biolink:NamedThing	biomineralization	The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products.	got7fsn_ti	mineralization|biomineralisation|mineralisation|biomineral formation						kmv	2019-06-10T17:55:28Z				Wikipedia:Biomineralization		biological_process											owl:Class	
GO:0050386	biolink:NamedThing	ureidosuccinase activity	Catalysis of the reaction: N-carbamoyl-L-aspartate + H(2)O + 2 H(+) = L-aspartate + CO(2) + NH(4)(+).	got7fsn_ti	N-carbamoyl-L-aspartate amidohydrolase activity											MetaCyc:UREIDOSUCCINASE-RXN|EC:3.5.1.7|KEGG_REACTION:R00484|RHEA:14365		molecular_function											owl:Class	
GO:0018160	biolink:NamedThing	peptidyl-pyrromethane cofactor linkage	The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.	got7fsn_ti	dipyrromethane cofactor binding|peptidyl-pyrromethane cofactor linkage via dipyrrolylmethanemethyl-L-cysteine										GO:0033035|GO:0018354	RESID:AA0252		biological_process											owl:Class	
GO:0018198	biolink:NamedThing	peptidyl-cysteine modification	The modification of peptidyl-cysteine.	got7fsn_ti														biological_process											owl:Class	
GO:0090216	biolink:NamedThing	positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	got7fsn_ti							tb	2010-01-12T10:00:45Z						biological_process											owl:Class	
GO:0090218	biolink:NamedThing	positive regulation of lipid kinase activity	Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.	got7fsn_ti							tb	2010-01-12T10:18:30Z						biological_process											owl:Class	
GO:0048658	biolink:NamedThing	anther wall tapetum development	The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure.	got7fsn_ti	tapetum development|tapetal layer development													biological_process											owl:Class	
GO:0048856	biolink:NamedThing	anatomical structure development	The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	got7fsn_ti	development of an anatomical structure													biological_process											owl:Class	
GO:0042391	biolink:NamedThing	regulation of membrane potential	Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0065008	biolink:NamedThing	regulation of biological quality	Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.	got7fsn_ti	regulation of biological attribute|regulation of biological characteristic													biological_process											owl:Class	
GO:1990216	biolink:NamedThing	positive regulation by symbiont of host transcription	Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-10T15:45:17Z						biological_process											owl:Class	
GO:0052026	biolink:NamedThing	modulation by symbiont of host transcription	Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0022021	biolink:NamedThing	caudal ganglionic eminence cell proliferation	The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0022012	biolink:NamedThing	subpallium cell proliferation in forebrain	The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0021676	biolink:NamedThing	rhombomere 8 structural organization	The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti	rhombomere 8 structural organisation													biological_process											owl:Class	
GO:0021595	biolink:NamedThing	rhombomere structural organization	The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.	got7fsn_ti	rhombomere structural organisation													biological_process											owl:Class	
GO:0042717	biolink:NamedThing	plasma membrane-derived chromatophore membrane	The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles.	got7fsn_ti														cellular_component											owl:Class	
GO:0034357	biolink:NamedThing	photosynthetic membrane	A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place.	got7fsn_ti														cellular_component											owl:Class	
GO:0036177	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to pH	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti							bf	2012-03-29T01:43:04Z						biological_process											owl:Class	
GO:0009268	biolink:NamedThing	response to pH	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti														biological_process											owl:Class	
GO:0010623	biolink:NamedThing	programmed cell death involved in cell development	The activation of endogenous cellular processes that result in the death of a cell as part of its development.	got7fsn_ti	programmed cell death involved in development|developmental programmed cell death				This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure.									biological_process											owl:Class	
GO:0048869	biolink:NamedThing	cellular developmental process	A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.	got7fsn_ti														biological_process											owl:Class	
GO:0110036	biolink:NamedThing	C2 domain binding	Binding to the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes.	got7fsn_ti							kmv	2017-07-20T20:45:56Z						molecular_function											owl:Class	
GO:0019904	biolink:NamedThing	protein domain specific binding	Binding to a specific domain of a protein.	got7fsn_ti	protein domain-specific binding													molecular_function											owl:Class	
GO:0047578	biolink:NamedThing	4-hydroxyglutamate transaminase activity	Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate.	got7fsn_ti	4-hydroxyglutamate aminotransferase activity|4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase activity											MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN|RHEA:10480|EC:2.6.1.23|Reactome:R-HSA-6784393		molecular_function											owl:Class	
GO:0008483	biolink:NamedThing	transaminase activity	Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.	got7fsn_ti	aminotransferase activity											Reactome:R-HSA-1237102|EC:2.6.1.-		molecular_function											owl:Class	
GO:0047906	biolink:NamedThing	fucosterol-epoxide lyase activity	Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol.	got7fsn_ti	(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase activity|(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)											KEGG_REACTION:R03723|EC:4.1.2.33|MetaCyc:FUCOSTEROL-EPOXIDE-LYASE-RXN|RHEA:10884		molecular_function											owl:Class	
GO:0016832	biolink:NamedThing	aldehyde-lyase activity	Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.	got7fsn_ti	aldolase activity										GO:0016228	EC:4.1.2.-		molecular_function											owl:Class	
GO:0036496	biolink:NamedThing	regulation of translational initiation by eIF2 alpha dephosphorylation	Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha.	got7fsn_ti							bf	2015-02-05T10:21:31Z						biological_process											owl:Class	
GO:0008152	biolink:NamedThing	metabolic process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.	got7fsn_ti	metabolism|metabolic process resulting in cell growth|single-organism metabolic process|multicellular organism metabolic process|metabolism resulting in cell growth				Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.		jl	2012-10-17T15:46:40Z			GO:0044236|GO:0044710	Wikipedia:Metabolism		biological_process											owl:Class	
GO:0019081	biolink:NamedThing	viral translation	A process by which viral mRNA is translated into viral protein, using the host cellular machinery.	got7fsn_ti	viral protein formation|viral protein synthesis|viral protein biosynthesis|viral protein anabolism|viral protein biosynthetic process													biological_process											owl:Class	
GO:0035041	biolink:NamedThing	sperm chromatin decondensation	Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus.	got7fsn_ti														biological_process											owl:Class	
GO:0006325	biolink:NamedThing	chromatin organization	Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.	got7fsn_ti	chromatin organisation|chromatin modification|establishment or maintenance of chromatin architecture										GO:0016568			biological_process											owl:Class	
GO:0002299	biolink:NamedThing	alpha-beta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	got7fsn_ti	alpha-beta intraepithelial T-lymphocyte differentiation|alpha-beta intraepithelial T cell development|alpha-beta intraepithelial T-cell differentiation|alpha-beta intraepithelial T lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0046632	biolink:NamedThing	alpha-beta T cell differentiation	The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.	got7fsn_ti	alpha-beta T-cell differentiation|alpha-beta T cell development|alpha-beta T lymphocyte differentiation|alpha-beta T-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1900049	biolink:NamedThing	regulation of histone exchange	Any process that modulates the frequency, rate or extent of histone exchange.	got7fsn_ti	regulation of histone displacement|regulation of histone chaperone|regulation of histone replacement						se	2012-01-19T10:59:02Z						biological_process											owl:Class	
GO:1902275	biolink:NamedThing	regulation of chromatin organization	Any process that modulates the frequency, rate or extent of chromatin organization.	got7fsn_ti	regulation of chromatin modification|regulation of establishment or maintenance of chromatin architecture|regulation of chromatin organisation						bf	2013-07-01T13:21:52Z			GO:1903308			biological_process											owl:Class	
GO:0060087	biolink:NamedThing	relaxation of vascular associated smooth muscle	A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.	got7fsn_ti	vascular smooth muscle relaxation|relaxation of vascular smooth muscle|positive regulation of relaxation of vascular smooth muscle|regulation of relaxation of vascular smooth muscle|negative regulation of relaxation of vascular smooth muscle										GO:1905657|GO:1905658|GO:1905659			biological_process											owl:Class	
GO:0044557	biolink:NamedThing	relaxation of smooth muscle	A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.	got7fsn_ti	smooth muscle relaxation						jl	2012-04-05T02:42:28Z						biological_process											owl:Class	
GO:0043571	biolink:NamedThing	maintenance of CRISPR repeat elements	Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences.	got7fsn_ti	maintenance of clustered regularly interspaced short palindromic repeat elements|CRISPR element metabolic process|CRISPR element metabolism													biological_process											owl:Class	
GO:0043570	biolink:NamedThing	maintenance of DNA repeat elements	Any process involved in sustaining the fidelity and copy number of DNA repeat elements.	got7fsn_ti														biological_process											owl:Class	
GO:0050985	biolink:NamedThing	peptidyl-threonine sulfation	The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine.	got7fsn_ti												RESID:AA0362		biological_process											owl:Class	
GO:0006477	biolink:NamedThing	protein sulfation	The addition of a sulfate group as an ester to a protein amino acid.	got7fsn_ti	protein amino acid sulfation|protein amino acid sulphation													biological_process											owl:Class	
GO:1900602	biolink:NamedThing	endocrocin biosynthetic process	The chemical reactions and pathways resulting in the formation of endocrocin.	got7fsn_ti	endocrocin biosynthesis|endocrocin formation|endocrocin synthesis|endocrocin anabolism						di	2012-05-15T06:57:42Z						biological_process											owl:Class	
GO:0044550	biolink:NamedThing	secondary metabolite biosynthetic process	The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.	got7fsn_ti	secondary metabolite biosynthesis						jl	2012-03-29T01:55:18Z						biological_process											owl:Class	
GO:0034857	biolink:NamedThing	2-(methylthio)benzothiazole monooxygenase activity	Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole.	got7fsn_ti												UM-BBD_reactionID:r1287		molecular_function											owl:Class	
GO:0016705	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.	got7fsn_ti	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous											EC:1.14.-.-		molecular_function											owl:Class	
GO:0070420	biolink:NamedThing	Ku-DNA ligase complex	A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria.	got7fsn_ti														cellular_component											owl:Class	
GO:0070419	biolink:NamedThing	nonhomologous end joining complex	A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.	got7fsn_ti	non-homologous end joining complex|NHEJ complex													cellular_component											owl:Class	
GO:0052805	biolink:NamedThing	imidazole-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.	got7fsn_ti	imidazole catabolism|imidazole degradation|imidazole breakdown													biological_process											owl:Class	
GO:0044270	biolink:NamedThing	cellular nitrogen compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.	got7fsn_ti	nitrogen compound catabolism|nitrogen compound breakdown|nitrogen compound degradation													biological_process											owl:Class	
GO:0031035	biolink:NamedThing	myosin filament disassembly	The disassembly of a filament composed of myosin molecules.	got7fsn_ti	myosin depolymerization													biological_process											owl:Class	
GO:0031033	biolink:NamedThing	myosin filament organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.	got7fsn_ti	myosin polymerization or depolymerization|myosin filament assembly or disassembly|myosin filament organisation				Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins; myosin structures are sufficiently closely associated with actin filaments to be included with the actin cytoskeleton.									biological_process											owl:Class	
GO:0011000	biolink:NamedThing	replication fork arrest at mating type locus	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.	got7fsn_ti							tb	2009-06-24T12:02:48Z						biological_process											owl:Class	
GO:0043111	biolink:NamedThing	replication fork arrest	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.	got7fsn_ti	replication fork stalling|negative regulation of DNA replication at replication fork barrier|replication fork blocking				See also the biological process term 'site-specific replication termination ; GO:0071170' and its children.									biological_process											owl:Class	
GO:0019365	biolink:NamedThing	pyridine nucleotide salvage	Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis.	got7fsn_ti	pyridine nucleotide cycling													biological_process											owl:Class	
GO:0043173	biolink:NamedThing	nucleotide salvage	Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.	got7fsn_ti												Wikipedia:Nucleotide_salvage		biological_process											owl:Class	
GO:0099646	biolink:NamedThing	neurotransmitter receptor transport, plasma membrane to endosome	Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome.	got7fsn_ti														biological_process											owl:Class	
GO:0048227	biolink:NamedThing	plasma membrane to endosome transport	Transport of a vesicle from the plasma membrane to the endosome.	got7fsn_ti														biological_process											owl:Class	
GO:1990736	biolink:NamedThing	regulation of vascular associated smooth muscle cell membrane depolarization	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell.	got7fsn_ti	regulation of vascular smooth muscle cell membrane depolarization						sl	2015-04-29T22:33:19Z						biological_process											owl:Class	
GO:0051899	biolink:NamedThing	membrane depolarization	The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti														biological_process											owl:Class	
GO:0018452	biolink:NamedThing	5-exo-hydroxycamphor dehydrogenase activity	Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane.	got7fsn_ti												RHEA:32879|EC:1.1.1.327|MetaCyc:R542-RXN|UM-BBD_reactionID:r0427		molecular_function											owl:Class	
GO:0016616	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.	got7fsn_ti	glycolate reductase|NADH-dependent glyoxylate reductase|glyoxylic acid reductase											Reactome:R-HSA-975629|EC:1.1.1.-		molecular_function											owl:Class	
GO:0009947	biolink:NamedThing	centrolateral axis specification	The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf.	got7fsn_ti	mediolateral axis specification|centrolateral axis determination													biological_process											owl:Class	
GO:0009798	biolink:NamedThing	axis specification	The establishment, maintenance and elaboration of a pattern along a line or around a point.	got7fsn_ti	axis determination													biological_process											owl:Class	
GO:0018555	biolink:NamedThing	phenanthrene dioxygenase activity	Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0455		molecular_function											owl:Class	
GO:0016702	biolink:NamedThing	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.	got7fsn_ti												Reactome:R-HSA-5164399|Reactome:R-HSA-9018880|Reactome:R-HSA-9020274|Reactome:R-HSA-9026408|EC:1.13.11.-|Reactome:R-HSA-2161907|Reactome:R-HSA-2161775|Reactome:R-HSA-2161917|Reactome:R-HSA-9026918		molecular_function											owl:Class	
GO:0005172	biolink:NamedThing	vascular endothelial growth factor receptor binding	Binding to a vascular endothelial growth factor receptor.	got7fsn_ti	VEGF receptor binding|vascular endothelial growth factor|vascular endothelial growth factor receptor ligand|VEGFR binding													molecular_function											owl:Class	
GO:0070851	biolink:NamedThing	growth factor receptor binding	Binding to a growth factor receptor.	got7fsn_ti							mah	2009-08-07T11:23:02Z						molecular_function											owl:Class	
GO:0140113	biolink:NamedThing	extracellular microvesicle biogenesis	The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding.	got7fsn_ti	extracellular microvesicle assembly	https://github.com/geneontology/go-ontology/issues/14256					pg	2017-10-23T12:00:11Z						biological_process											owl:Class	
GO:0140112	biolink:NamedThing	extracellular vesicle biogenesis	The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.	got7fsn_ti	extracellular vesicle assembly	https://github.com/geneontology/go-ontology/issues/14256					pg	2017-10-23T11:53:42Z						biological_process											owl:Class	
GO:0031250	biolink:NamedThing	anaerobic ribonucleoside-triphosphate reductase complex	An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit.	got7fsn_ti														cellular_component											owl:Class	
GO:0032991	biolink:NamedThing	protein-containing complex	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	got7fsn_ti	protein-protein complex|macromolecular complex|protein complex|protein containing complex|macromolecule complex				A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.						GO:0043234			cellular_component											owl:Class	
GO:0046294	biolink:NamedThing	formaldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.	got7fsn_ti	formaldehyde degradation|formaldehyde breakdown|methanal catabolic process|formaldehyde catabolism|methanal catabolism													biological_process											owl:Class	
GO:0044282	biolink:NamedThing	small molecule catabolic process	The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.	got7fsn_ti	small molecule catabolism				Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.		jl	2010-01-26T12:06:10Z						biological_process											owl:Class	
GO:0071133	biolink:NamedThing	alpha9-beta1 integrin-ADAM8 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.	got7fsn_ti	ITGA9-ITGB1-ADAM8 complex						mah	2009-11-13T02:28:49Z						cellular_component											owl:Class	
GO:0007636	biolink:NamedThing	chemosensory jump behavior	The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance.	got7fsn_ti	jump response to chemical stimulus|chemosensory jump behaviour													biological_process											owl:Class	
GO:0007635	biolink:NamedThing	chemosensory behavior	Behavior that is dependent upon the sensation of chemicals.	got7fsn_ti	chemosensory behaviour|behavioural response to chemical stimulus|behavioral response to chemical stimulus													biological_process											owl:Class	
GO:0060592	biolink:NamedThing	mammary gland formation	The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.	got7fsn_ti	mammary line formation|mammary placode formation|mammary sprout formation|mammary bud formation						dph	2009-05-13T08:47:52Z						biological_process											owl:Class	
GO:0035740	biolink:NamedThing	CD8-positive, alpha-beta T cell proliferation	The expansion of a CD8-positive, alpha-beta T cell population by cell division.	got7fsn_ti							bf	2011-03-17T02:13:54Z						biological_process											owl:Class	
GO:0036037	biolink:NamedThing	CD8-positive, alpha-beta T cell activation	The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti							bf	2011-11-03T10:34:12Z						biological_process											owl:Class	
GO:0097674	biolink:NamedThing	SCF-YLR352W ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae.	got7fsn_ti							pr	2014-10-06T10:30:54Z						cellular_component											owl:Class	
GO:0019005	biolink:NamedThing	SCF ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).	got7fsn_ti	CDL1 complex|cullin-RING ligase 1|SCF complex|CRL1 complex|SCF complex substrate recognition subunit|Cul1-RING ubiquitin ligase complex|Skp1/Cul1/F-box protein complex											Wikipedia:SCF_complex		cellular_component											owl:Class	
GO:0030532	biolink:NamedThing	small nuclear ribonucleoprotein complex	A ribonucleoprotein complex that contains at least one RNA of the small nuclear RNA (snRNA) class and as well as its associated proteins. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP, U4/U6 snRNP, or 7SK snRNP. Many, of these complexes become part of the spliceosome involved in splicing of nuclear mRNAs. Others are involved in regulation of transcription elongation or 3'-end processing of replication-dependent histone pre-mRNAs.	got7fsn_ti	small nuclear ribonucleoprotein|snRNP											Wikipedia:SnRNP		cellular_component											owl:Class	
GO:0140513	biolink:NamedThing	nuclear protein-containing complex	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus.	got7fsn_ti	nuclear complex						pg	2020-09-09T05:12:38Z						cellular_component											owl:Class	
GO:0034039	biolink:NamedThing	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar.	got7fsn_ti	8-oxoG DNA N-glycosylase activity													molecular_function											owl:Class	
GO:0008534	biolink:NamedThing	oxidized purine nucleobase lesion DNA N-glycosylase activity	Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.	got7fsn_ti	DNA glycosylase/AP-lyase activity|DNA glycosylase/beta-lyase activity|oxidized purine base lesion DNA N-glycosylase activity|8-oxoguanine DNA glycosylase activity|2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity|formamidopyrimidine-DNA glycosylase activity|Fapy-DNA glycosylase activity|2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity|DNA-formamidopyrimidine glycosylase activity|purine-specific oxidized base lesion DNA N-glycosylase activity|bifunctional DNA glycosylase activity|Fpg protein|deoxyribonucleate glycosidase activity|DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing]				Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'.						GO:0003907	Reactome:R-HSA-110244|MetaCyc:3.2.2.23-RXN|Reactome:R-HSA-110229|Reactome:R-HSA-110243|EC:3.2.2.23		molecular_function											owl:Class	
GO:0044186	biolink:NamedThing	host cell lipid droplet	Any particle of coalesced lipids in the cytoplasm of a host cell. May include associated proteins.	got7fsn_ti	host cell lipid particle|host cell lipid adiposome|host cell lipid body						jl	2009-10-15T03:05:06Z						cellular_component											owl:Class	
GO:0033655	biolink:NamedThing	host cell cytoplasm part	Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	cytoplasm component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									cellular_component											owl:Class	
GO:0010723	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to iron	Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0034395	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to iron	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus.	got7fsn_ti	regulation of specific transcription from RNA polymerase II promoter in response to iron													biological_process											owl:Class	
GO:0090532	biolink:NamedThing	L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate	The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate.	got7fsn_ti	L-ascorbic acid biosynthesis via UDP-alpha-D-glucuronate				This pathway occurs in most vertebrates, although not in guinea pigs and primates, including humans.		tb	2013-02-06T15:31:01Z						biological_process											owl:Class	
GO:0019853	biolink:NamedThing	L-ascorbic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.	got7fsn_ti	L-ascorbic acid formation|vitamin C biosynthesis|L-ascorbic acid anabolism|ascorbate biosynthesis|L-ascorbic acid biosynthesis|ascorbate biosynthetic process|vitamin C biosynthetic process|L-ascorbic acid synthesis											MetaCyc:PWY-882		biological_process											owl:Class	
GO:0009404	biolink:NamedThing	toxin metabolic process	The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.	got7fsn_ti	toxin metabolism													biological_process											owl:Class	
GO:0019748	biolink:NamedThing	secondary metabolic process	The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.	got7fsn_ti	secondary metabolite metabolic process|secondary metabolite metabolism|secondary metabolism											Wikipedia:Secondary_metabolism		biological_process											owl:Class	
GO:0043891	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+.	got7fsn_ti	triosephosphate dehydrogenase (NAD(P))|glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)|triosephosphate dehydrogenase (NAD(P)+)|NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity|D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)											MetaCyc:GAPDHSYNEC-RXN|EC:1.2.1.59		molecular_function											owl:Class	
GO:0016620	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.	got7fsn_ti												Reactome:R-HSA-1222583|EC:1.2.1.-		molecular_function											owl:Class	
GO:0045457	biolink:NamedThing	ecdysteroid secretion	The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.	got7fsn_ti														biological_process											owl:Class	
GO:0035929	biolink:NamedThing	steroid hormone secretion	The regulated release of any steroid that acts as a hormone into the circulatory system.	got7fsn_ti							bf	2011-07-20T01:01:00Z						biological_process											owl:Class	
GO:0019151	biolink:NamedThing	galactose 1-dehydrogenase activity	Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+.	got7fsn_ti	beta-galactose dehydrogenase activity|D-galactose 1-dehydrogenase activity|NAD-dependent D-galactose dehydrogenase activity|D-galactose:NAD+ 1-oxidoreductase activity|D-galactose dehydrogenase activity											RHEA:21296|MetaCyc:GALACTODEHYDROG-RXN|EC:1.1.1.48		molecular_function											owl:Class	
GO:0033720	biolink:NamedThing	(S)-mandelate dehydrogenase activity	Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor.	got7fsn_ti	MDH|(S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase activity|L(+)-mandelate dehydrogenase activity											MetaCyc:MANDELATE-DEHYDROGENASE-RXN|RHEA:15749|UM-BBD_reactionID:r1048|MetaCyc:MANDELATE-OXY-RXN|EC:1.1.99.31		molecular_function											owl:Class	
GO:0016614	biolink:NamedThing	oxidoreductase activity, acting on CH-OH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on the CH-OH group of donors, other acceptors											EC:1.1.-.-|Reactome:R-HSA-1500781		molecular_function											owl:Class	
GO:0002182	biolink:NamedThing	cytoplasmic translational elongation	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.	got7fsn_ti							hjd	2011-06-09T03:14:42Z						biological_process											owl:Class	
GO:0006414	biolink:NamedThing	translational elongation	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.	got7fsn_ti	translation elongation|protein synthesis elongation										GO:0006442|GO:0006455			biological_process											owl:Class	
GO:0150015	biolink:NamedThing	apical proximal dendrite	The dendrite of the dendritic tree, which emerges near the apical pole of a neuron, and which is the closest to the cell body of the neuron (the soma).	got7fsn_ti							bc	2017-12-21T12:09:26Z						cellular_component											owl:Class	
GO:1990635	biolink:NamedThing	proximal dendrite	The dendrite of the dendritic tree that is closest to the neuronal cell body (the soma).	got7fsn_ti							sl	2015-02-10T22:57:16Z						cellular_component											owl:Class	
GO:0003904	biolink:NamedThing	deoxyribodipyrimidine photo-lyase activity	Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light.	got7fsn_ti	CPD photolyase activity|phr A photolyase activity|deoxyribonucleic cyclobutane dipyrimidine photolyase activity|PhrB photolyase activity|deoxyribocyclobutadipyrimidine pyrimidine-lyase activity|PRE|photoreactivating enzyme activity|deoxyribonucleic photolyase activity|dipyrimidine photolyase (photosensitive)|photolyase activity|deoxyribodipyrimidine photolyase activity|DNA-photoreactivating enzyme|DNA cyclobutane dipyrimidine photolyase activity|deoxyribonucleate pyrimidine dimer lyase (photosensitive)											MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN|RHEA:10672|EC:4.1.99.3		molecular_function											owl:Class	
GO:0003913	biolink:NamedThing	DNA photolyase activity	Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA.	got7fsn_ti												MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN		molecular_function											owl:Class	
GO:0046992	biolink:NamedThing	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y.	got7fsn_ti	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors											EC:1.21.-.-		molecular_function											owl:Class	
GO:0016491	biolink:NamedThing	oxidoreductase activity	Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.	got7fsn_ti	oxidoreductase activity, acting on other substrates|redox activity											Reactome:R-HSA-209960|Reactome:R-HSA-9024624|Reactome:R-HSA-8878581|Reactome:R-HSA-9027033|Reactome:R-HSA-3095889|Reactome:R-HSA-9020260|Reactome:R-HSA-9024630|Reactome:R-HSA-9020249|EC:1.-.-.-|Reactome:R-HSA-5662660|Reactome:R-HSA-8936442|Reactome:R-HSA-9026917|Reactome:R-HSA-209921|Reactome:R-HSA-1614362|Reactome:R-HSA-9693722|Reactome:R-HSA-390425|Reactome:R-HSA-9025007|Reactome:R-HSA-390438|Reactome:R-HSA-9026001		molecular_function											owl:Class	
GO:0030169	biolink:NamedThing	low-density lipoprotein particle binding	Binding to a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.	got7fsn_ti	LDL binding													molecular_function											owl:Class	
GO:0071813	biolink:NamedThing	lipoprotein particle binding	Binding to a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.	got7fsn_ti	plasma lipoprotein particle binding|lipoprotein binding|plasma lipoprotein binding						mah	2010-09-06T03:16:01Z						molecular_function											owl:Class	
GO:0071320	biolink:NamedThing	cellular response to cAMP	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.	got7fsn_ti	cellular response to cyclic AMP|cellular response to adenosine 3',5'-cyclophosphate|cellular response to 3',5' cAMP|cellular response to 3',5'-cAMP						mah	2009-12-10T05:12:15Z						biological_process											owl:Class	
GO:0051591	biolink:NamedThing	response to cAMP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.	got7fsn_ti	response to 3',5' cAMP|response to adenosine 3',5'-cyclophosphate|response to cyclic AMP|response to 3',5'-cAMP													biological_process											owl:Class	
GO:0003233	biolink:NamedThing	bulbus arteriosus morphogenesis	The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber.	got7fsn_ti							dph	2009-10-13T11:07:30Z						biological_process											owl:Class	
GO:0003206	biolink:NamedThing	cardiac chamber morphogenesis	The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.	got7fsn_ti	heart chamber morphogenesis						dph	2009-10-13T09:14:51Z						biological_process											owl:Class	
GO:0006314	biolink:NamedThing	intron homing	Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron.	got7fsn_ti														biological_process											owl:Class	
GO:0006310	biolink:NamedThing	DNA recombination	Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.	got7fsn_ti														biological_process											owl:Class	
GO:0071364	biolink:NamedThing	cellular response to epidermal growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.	got7fsn_ti	cellular response to EGF stimulus						mah	2009-12-11T03:05:34Z						biological_process											owl:Class	
GO:0070849	biolink:NamedThing	response to epidermal growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.	got7fsn_ti	response to epidermal growth factor stimulus|response to EGF stimulus						mah	2009-08-04T04:26:26Z						biological_process											owl:Class	
GO:0098579	biolink:NamedThing	active sex chromosome	A sex chromosome that has not been inactivated.	got7fsn_ti														cellular_component											owl:Class	
GO:0000803	biolink:NamedThing	sex chromosome	A chromosome involved in sex determination.	got7fsn_ti														cellular_component											owl:Class	
GO:0106283	biolink:NamedThing	ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity	Catalysis of the reaction: NAD(+) + ursodeoxycholate = 7-oxolithocholate + H(+) + NADH.	got7fsn_ti							hjd	2020-07-29T17:52:44Z				RHEA:42028		molecular_function											owl:Class	
GO:0033764	biolink:NamedThing	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0097051	biolink:NamedThing	establishment of protein localization to endoplasmic reticulum membrane	The directed movement of a protein to a specific location in the endoplasmic reticulum membrane.	got7fsn_ti	establishment of protein localisation in endoplasmic reticulum membrane|establishment of protein localization in endoplasmic reticulum membrane						pr	2011-05-04T05:55:26Z						biological_process											owl:Class	
GO:0090150	biolink:NamedThing	establishment of protein localization to membrane	The directed movement of a protein to a specific location in a membrane.	got7fsn_ti	establishment of protein localization in membrane|establishment of protein localisation in membrane						tb	2009-12-08T03:18:51Z						biological_process											owl:Class	
GO:0008710	biolink:NamedThing	8-amino-7-oxononanoate synthase activity	Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA.	got7fsn_ti	7-keto-8-aminopelargonic synthetase activity|7-keto-8-aminopelargonic acid synthetase activity|7-keto-8-amino-pelargonic acid synthetase activity|6-carboxyhexanoyl-CoA:L-alanine C-carboxyhexanoyltransferase (decarboxylating)|8-amino-7-ketopelargonate synthase activity|7-KAP synthetase activity|AONS activity|8-amino-7-oxopelargonate synthase activity											KEGG_REACTION:R03210|RHEA:20712|MetaCyc:7KAPSYN-RXN|EC:2.3.1.47		molecular_function											owl:Class	
GO:0016747	biolink:NamedThing	acyltransferase activity, transferring groups other than amino-acyl groups	Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring acyl groups other than amino-acyl groups|transferase activity, transferring groups other than amino-acyl groups	https://github.com/geneontology/go-ontology/issues/20486										EC:2.3.1.-		molecular_function											owl:Class	
GO:0046838	biolink:NamedThing	phosphorylated carbohydrate dephosphorylation	The process of removing a phosphate group from a phosphorylated carbohydrate, any organic compound based on the general formula Cx(H2O)y with a phosphate group attached to it.	got7fsn_ti														biological_process											owl:Class	
GO:0044262	biolink:NamedThing	cellular carbohydrate metabolic process	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	got7fsn_ti	cellular carbohydrate metabolism|main pathways of carbohydrate metabolic process|main pathways of carbohydrate metabolism										GO:0006092			biological_process											owl:Class	
GO:0031990	biolink:NamedThing	mRNA export from nucleus in response to heat stress	The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export.	got7fsn_ti	mRNA export from nucleus during heat stress|mRNA export from cell nucleus during heat stress													biological_process											owl:Class	
GO:0034605	biolink:NamedThing	cellular response to heat	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	got7fsn_ti	cellular response to heat stress													biological_process											owl:Class	
GO:0060562	biolink:NamedThing	epithelial tube morphogenesis	The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.	got7fsn_ti							dph	2009-04-28T09:33:36Z						biological_process											owl:Class	
GO:0035239	biolink:NamedThing	tube morphogenesis	The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.	got7fsn_ti														biological_process											owl:Class	
GO:0007072	biolink:NamedThing	positive regulation of transcription involved in exit from mitosis	Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	got7fsn_ti	activation of transcription on exit from mitosis													biological_process											owl:Class	
GO:0022402	biolink:NamedThing	cell cycle process	The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.	got7fsn_ti														biological_process											owl:Class	
GO:0075209	biolink:NamedThing	induction by symbiont of host cAMP-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host cAMP-mediated signaling|positive regulation by symbiont of host cAMP-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont cAMP-mediated signal transduction ; GO:0075206".									biological_process											owl:Class	
GO:0075208	biolink:NamedThing	modulation by symbiont of host cAMP-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host cAMP-mediated signaling				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont cAMP-mediated signal transduction ; GO:0075205".									biological_process											owl:Class	
GO:0102648	biolink:NamedThing	D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity	Catalysis of the reaction: D-fructose 6-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-glyceraldehyde 3-phosphate.	got7fsn_ti												MetaCyc:RXN-15790		molecular_function											owl:Class	
GO:0016744	biolink:NamedThing	transketolase or transaldolase activity	Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring aldehyde or ketonic groups	https://github.com/geneontology/go-ontology/issues/20486									GO:0016745	EC:2.2.1.-		molecular_function											owl:Class	
GO:0044630	biolink:NamedThing	modulation of complement activation, lectin pathway in other organism	A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism.	got7fsn_ti	regulation of complement activation, lectin pathway in other organism						jl	2012-07-05T01:10:31Z						biological_process											owl:Class	
GO:0001868	biolink:NamedThing	regulation of complement activation, lectin pathway	Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation.	got7fsn_ti	regulation of complement cascade, lectin pathway													biological_process											owl:Class	
GO:0001626	biolink:NamedThing	nociceptin receptor activity	Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein.	got7fsn_ti	OFQ receptor activity|nociceptin/orphanin-FQ receptor activity|orphanin-FQ receptor activity|ORPH receptor|X-opioid receptor activity													molecular_function											owl:Class	
GO:0004985	biolink:NamedThing	G protein-coupled opioid receptor activity	Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein.	got7fsn_ti	opioid receptor activity	https://github.com/geneontology/go-ontology/issues/21110												molecular_function											owl:Class	
GO:0030655	biolink:NamedThing	beta-lactam antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.	got7fsn_ti	beta-lactam antibiotic catabolism|beta-lactam antibiotic degradation|beta-lactam antibiotic breakdown													biological_process											owl:Class	
GO:0072340	biolink:NamedThing	cellular lactam catabolic process	The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	got7fsn_ti	cellular lactam breakdown|cellular lactam degradation|cellular lactam catabolism						mah	2010-11-04T04:33:22Z						biological_process											owl:Class	
GO:0007269	biolink:NamedThing	neurotransmitter secretion	The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.	got7fsn_ti	neurotransmitter release|neurotransmitter secretory pathway				A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.						GO:0010554			biological_process											owl:Class	
GO:0023061	biolink:NamedThing	signal release	The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.	got7fsn_ti	signal secretion							2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0046377	biolink:NamedThing	colanic acid metabolic process	The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues.	got7fsn_ti	colanic acid metabolism													biological_process											owl:Class	
GO:0044264	biolink:NamedThing	cellular polysaccharide metabolic process	The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.	got7fsn_ti	cellular glycan metabolic process|cellular glycan metabolism|cellular polysaccharide metabolism													biological_process											owl:Class	
GO:0007158	biolink:NamedThing	neuron cell-cell adhesion	The attachment of a neuron to another cell via adhesion molecules.	got7fsn_ti	neuron adhesion|neuronal cell adhesion													biological_process											owl:Class	
GO:0098609	biolink:NamedThing	cell-cell adhesion	The attachment of one cell to another cell via adhesion molecules.	got7fsn_ti	single organismal cell-cell adhesion						dos	2014-04-16T13:40:03Z			GO:0016337			biological_process											owl:Class	
GO:0001894	biolink:NamedThing	tissue homeostasis	A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.	got7fsn_ti	tissue maintenance													biological_process											owl:Class	
GO:0060249	biolink:NamedThing	anatomical structure homeostasis	A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	got7fsn_ti	anatomical structure maintenance													biological_process											owl:Class	
GO:0018220	biolink:NamedThing	peptidyl-threonine palmitoylation	The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine.	got7fsn_ti	peptidyl-threonine O-palmitoylation				Palmitoylation of a non-terminal threonine residue always occurs on an oxygen (O) atom.							RESID:AA0079		biological_process											owl:Class	
GO:0018210	biolink:NamedThing	peptidyl-threonine modification	The modification of peptidyl-threonine.	got7fsn_ti														biological_process											owl:Class	
GO:0098920	biolink:NamedThing	retrograde trans-synaptic signaling by lipid	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.	got7fsn_ti														biological_process											owl:Class	
GO:0099537	biolink:NamedThing	trans-synaptic signaling	Cell-cell signaling in either direction across the synaptic cleft.	got7fsn_ti														biological_process											owl:Class	
GO:0021589	biolink:NamedThing	cerebellum structural organization	The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	got7fsn_ti	cerebellum structural organisation													biological_process											owl:Class	
GO:0048532	biolink:NamedThing	anatomical structure arrangement	The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	got7fsn_ti	structural organization|anatomical structure structural organization|anatomical structure organization|organization of an anatomical structure													biological_process											owl:Class	
GO:0097230	biolink:NamedThing	cell motility in response to potassium ion	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus.	got7fsn_ti	potassium ion facilitation of cell motility|K+ facilitation of cell motility						pr	2012-01-25T04:39:45Z						biological_process											owl:Class	
GO:0048870	biolink:NamedThing	cell motility	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.	got7fsn_ti	movement of a cell|cell locomotion|cell movement													biological_process											owl:Class	
GO:0015195	biolink:NamedThing	L-threonine transmembrane transporter activity	Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid.	got7fsn_ti	threonine/serine:sodium symporter activity|L-threonine permease activity|L-threonine transporter activity										GO:0015512			molecular_function											owl:Class	
GO:0015175	biolink:NamedThing	neutral amino acid transmembrane transporter activity	Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3.	got7fsn_ti	neutral amino acid transporter activity													molecular_function											owl:Class	
GO:0009041	biolink:NamedThing	uridylate kinase activity	Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.	got7fsn_ti												EC:2.7.4.22		molecular_function											owl:Class	
GO:0016776	biolink:NamedThing	phosphotransferase activity, phosphate group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor).	got7fsn_ti												EC:2.7.4.-		molecular_function											owl:Class	
GO:0006869	biolink:NamedThing	lipid transport	The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.	got7fsn_ti														biological_process											owl:Class	
GO:0030724	biolink:NamedThing	testicular fusome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.	got7fsn_ti	testicular fusome organisation|testicular fusome organization and biogenesis													biological_process											owl:Class	
GO:0045478	biolink:NamedThing	fusome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells.	got7fsn_ti	fusome organisation|fusome organization and biogenesis													biological_process											owl:Class	
GO:0032298	biolink:NamedThing	positive regulation of DNA-dependent DNA replication initiation	Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.	got7fsn_ti	stimulation of DNA replication initiation|up-regulation of DNA replication initiation|negative regulation of DNA replication initiation|upregulation of DNA replication initiation|up regulation of DNA replication initiation|activation of DNA replication initiation													biological_process											owl:Class	
GO:0045740	biolink:NamedThing	positive regulation of DNA replication	Any process that activates or increases the frequency, rate or extent of DNA replication.	got7fsn_ti	stimulation of DNA replication|upregulation of DNA replication|up regulation of DNA replication|up-regulation of DNA replication|activation of DNA replication													biological_process											owl:Class	
GO:0099135	biolink:NamedThing	chimeric colonial development	Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.	got7fsn_ti														biological_process											owl:Class	
GO:0099120	biolink:NamedThing	socially cooperative development	The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are  spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies.	got7fsn_ti	socially co-operative development|non-reproductive fruiting body development|colonial development	https://github.com/geneontology/go-ontology/issues/20428									GO:0090702			biological_process											owl:Class	
GO:0044277	biolink:NamedThing	cell wall disassembly	A process that results in the breakdown of the cell wall.	got7fsn_ti	cellular cell wall disassembly						jl	2010-01-14T02:00:34Z			GO:0060871			biological_process											owl:Class	
GO:0071555	biolink:NamedThing	cell wall organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	got7fsn_ti	cellular cell wall organisation|cell wall organisation in other organism|cell wall organization at cellular level|cell wall organisation|cell wall organization and biogenesis|cellular cell wall organization|cell wall organization in other organism						mah	2010-01-13T03:33:07Z			GO:0044234|GO:0007047			biological_process											owl:Class	
GO:0033880	biolink:NamedThing	phenylacetyl-CoA hydrolase activity	Catalysis of the reaction: H(2)O + phenylglyoxylyl-CoA = CoA + H(+) + phenylglyoxylate.	got7fsn_ti	phenylglyoxylyl-CoA hydrolase activity											MetaCyc:3.1.2.25-RXN|RHEA:15337|EC:3.1.2.25|KEGG_REACTION:R07294		molecular_function											owl:Class	
GO:0016289	biolink:NamedThing	CoA hydrolase activity	Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.	got7fsn_ti												Reactome:R-HSA-193385		molecular_function											owl:Class	
GO:0006259	biolink:NamedThing	DNA metabolic process	Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.	got7fsn_ti	DNA metabolism|cellular DNA metabolism										GO:0055132			biological_process											owl:Class	
GO:0044260	biolink:NamedThing	cellular macromolecule metabolic process	The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.	got7fsn_ti	cellular macromolecule metabolism|cellular biopolymer metabolic process										GO:0034960			biological_process											owl:Class	
GO:0034210	biolink:NamedThing	sterol deacetylation	The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti														biological_process											owl:Class	
GO:0034208	biolink:NamedThing	steroid deacetylation	The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti														biological_process											owl:Class	
GO:0030866	biolink:NamedThing	cortical actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.	got7fsn_ti	cortical actin cytoskeleton stabilization|actin cortex stabilization|cortical resistance|cortical actin cytoskeleton organisation|cortical actin cytoskeleton organization and biogenesis										GO:0033109			biological_process											owl:Class	
GO:0030036	biolink:NamedThing	actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.	got7fsn_ti	actin cytoskeleton organization and biogenesis|actin cytoskeleton organisation|actin modulating activity													biological_process											owl:Class	
GO:0036185	biolink:NamedThing	13-lipoxin reductase activity	Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+.	got7fsn_ti							bf	2012-04-16T02:28:19Z				Reactome:R-HSA-2161844		molecular_function											owl:Class	
GO:0035597	biolink:NamedThing	N6-isopentenyladenosine methylthiotransferase activity	Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).	got7fsn_ti	i6A methylthiotransferase activity						bf	2010-11-12T01:26:58Z						molecular_function											owl:Class	
GO:0035596	biolink:NamedThing	methylthiotransferase activity	Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.	got7fsn_ti	MTTase						bf	2010-11-12T01:24:38Z						molecular_function											owl:Class	
GO:0042085	biolink:NamedThing	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.	got7fsn_ti														molecular_function											owl:Class	
GO:0008168	biolink:NamedThing	methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule.	got7fsn_ti	methylase										GO:0004480	Reactome:R-HSA-379387|Reactome:R-HSA-379464|Reactome:R-HSA-71286|EC:2.1.1.-|Reactome:R-HSA-6800149|Reactome:R-HSA-212269		molecular_function											owl:Class	
GO:0032103	biolink:NamedThing	positive regulation of response to external stimulus	Any process that activates, maintains or increases the rate of a response to an external stimulus.	got7fsn_ti	stimulation of response to external stimulus|up regulation of response to external stimulus|activation of response to external stimulus|up-regulation of response to external stimulus|upregulation of response to external stimulus				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0032101	biolink:NamedThing	regulation of response to external stimulus	Any process that modulates the frequency, rate or extent of a response to an external stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0035127	biolink:NamedThing	post-embryonic limb morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.	got7fsn_ti														biological_process											owl:Class	
GO:0035108	biolink:NamedThing	limb morphogenesis	The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.	got7fsn_ti	limb bud morphogenesis													biological_process											owl:Class	
GO:0071175	biolink:NamedThing	MAML2-RBP-Jkappa-ICN1 complex	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML2-RBP-Jkappa-Notch1 complex						mah	2009-11-23T02:36:28Z						cellular_component											owl:Class	
GO:0006602	biolink:NamedThing	creatinine catabolic process	The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.	got7fsn_ti	creatinine degradation|creatinine catabolism|creatinine breakdown													biological_process											owl:Class	
GO:0009974	biolink:NamedThing	zeinoxanthin epsilon hydroxylase activity	Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.	got7fsn_ti												MetaCyc:RXN-5962|RHEA:57352|EC:1.14.14.158		molecular_function											owl:Class	
GO:0072374	biolink:NamedThing	carotene epsilon hydroxylase activity	Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.	got7fsn_ti							mah	2010-11-19T03:57:55Z						molecular_function											owl:Class	
GO:0035526	biolink:NamedThing	retrograde transport, plasma membrane to Golgi	The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles.	got7fsn_ti							bf	2010-05-05T10:52:49Z						biological_process											owl:Class	
GO:0016192	biolink:NamedThing	vesicle-mediated transport	A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.	got7fsn_ti	vesicular transport|vesicle trafficking|vesicle transport|protein sorting along secretory pathway|nonselective vesicle transport										GO:0006899			biological_process											owl:Class	
GO:0106301	biolink:NamedThing	arachidonic acid 5,6-epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-5,6-epoxyeicosatrienoic acid.	got7fsn_ti							hjd	2020-08-28T19:08:45Z				RHEA:49936		molecular_function											owl:Class	
GO:0008392	biolink:NamedThing	arachidonic acid epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.	got7fsn_ti	cytochrome P450 CYP2J5|cytochrome P450 CYP2J6											Reactome:R-HSA-211983		molecular_function											owl:Class	
GO:0033371	biolink:NamedThing	T cell secretory granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.	got7fsn_ti	T lymphocyte secretory granule organization|T-lymphocyte secretory granule maturation|T-lymphocyte secretory granule organization|T cell secretory granule organization and biogenesis|T cell secretory granule organisation|T-cell secretory granule organization													biological_process											owl:Class	
GO:0033363	biolink:NamedThing	secretory granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.	got7fsn_ti	secretory granule organisation|secretory granule organization and biogenesis													biological_process											owl:Class	
GO:0030900	biolink:NamedThing	forebrain development	The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).	got7fsn_ti	prosencephalon development													biological_process											owl:Class	
GO:0055121	biolink:NamedThing	response to high fluence blue light stimulus by blue high-fluence system	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2.	got7fsn_ti	response to high fluence blue light|response to high fluence blue light by bhf system													biological_process											owl:Class	
GO:0009637	biolink:NamedThing	response to blue light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.	got7fsn_ti	response to blue light stimulus													biological_process											owl:Class	
GO:0045013	biolink:NamedThing	carbon catabolite repression of transcription	A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.	got7fsn_ti	negative regulation of transcription by carbon catabolites|carbon catabolite repression													biological_process											owl:Class	
GO:0045892	biolink:NamedThing	negative regulation of transcription, DNA-templated	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	got7fsn_ti	negative regulation of gene-specific transcription|downregulation of gene-specific transcription|negative regulation of cellular transcription, DNA-dependent|transcription repressor activity|inhibition of transcription, DNA-dependent|downregulation of transcription, DNA-dependent|down regulation of transcription, DNA-dependent|down-regulation of gene-specific transcription|inhibition of gene-specific transcription|down-regulation of transcription, DNA-dependent|negative regulation of transcription, DNA-dependent|down regulation of gene-specific transcription										GO:0016481|GO:0061021|GO:0032582			biological_process											owl:Class	
GO:0035799	biolink:NamedThing	ureter maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.	got7fsn_ti							bf	2011-04-14T01:13:39Z						biological_process											owl:Class	
GO:0048799	biolink:NamedThing	animal organ maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions.	got7fsn_ti														biological_process											owl:Class	
GO:0048789	biolink:NamedThing	cytoskeletal matrix organization at active zone	The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.	got7fsn_ti	cytoskeletal matrix organisation at active zone													biological_process											owl:Class	
GO:0030865	biolink:NamedThing	cortical cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.	got7fsn_ti	cortical cytoskeleton organization and biogenesis|cortical cytoskeleton organisation													biological_process											owl:Class	
GO:0071668	biolink:NamedThing	plant-type cell wall assembly	The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall.	got7fsn_ti	plant cell wall assembly						mah	2010-02-15T02:19:39Z						biological_process											owl:Class	
GO:0070726	biolink:NamedThing	cell wall assembly	The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.	got7fsn_ti							mah	2009-06-16T03:58:20Z						biological_process											owl:Class	
GO:0085039	biolink:NamedThing	hyphal membrane	A host-derived membrane surrounding the symbiont hypha during infection.	got7fsn_ti	extra-invasive hyphal membrane	https://github.com/geneontology/go-ontology/issues/19013					jl	2010-07-27T04:19:46Z						cellular_component											owl:Class	
GO:0033644	biolink:NamedThing	host cell membrane	Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														cellular_component											owl:Class	
GO:0072154	biolink:NamedThing	proximal convoluted tubule segment 1 cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney.	got7fsn_ti	S1 cell fate commitment						mah	2010-02-24T02:18:19Z						biological_process											owl:Class	
GO:0045165	biolink:NamedThing	cell fate commitment	The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.	got7fsn_ti					Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created.									biological_process											owl:Class	
GO:0051332	biolink:NamedThing	meiotic S phase	The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.	got7fsn_ti	S phase of meiotic cell cycle|S-phase of meiotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0051320	biolink:NamedThing	S phase	The cell cycle phase, following G1, during which DNA synthesis takes place.	got7fsn_ti	S-phase				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:S_phase		biological_process											owl:Class	
GO:0036268	biolink:NamedThing	swimming	Self-propelled movement of an organism from one location to another through water, often by means of active fin movement.	got7fsn_ti					For behavioral aspects of swimming, consider instead annotating to 'swimming behavior ; GO:0036269'.		bf	2012-07-04T10:12:24Z						biological_process											owl:Class	
GO:0040011	biolink:NamedThing	locomotion	Self-propelled movement of a cell or organism from one location to another.	got7fsn_ti														biological_process											owl:Class	
GO:0090326	biolink:NamedThing	positive regulation of locomotion involved in locomotory behavior	Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.	got7fsn_ti							tb	2010-05-14T10:26:58Z						biological_process											owl:Class	
GO:0040017	biolink:NamedThing	positive regulation of locomotion	Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.	got7fsn_ti	activation of locomotion|up regulation of locomotion|up-regulation of locomotion|stimulation of locomotion|upregulation of locomotion													biological_process											owl:Class	
GO:0070054	biolink:NamedThing	mRNA splicing, via endonucleolytic cleavage and ligation	Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.	got7fsn_ti	cytosolic mRNA splicing				Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.						GO:0061012			biological_process											owl:Class	
GO:0000394	biolink:NamedThing	RNA splicing, via endonucleolytic cleavage and ligation	Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.	got7fsn_ti	mRNA splicing				Note that while typically associated with tRNA splicing, this mechanism of splicing is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.									biological_process											owl:Class	
GO:0015026	biolink:NamedThing	coreceptor activity	Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.	got7fsn_ti	coreceptor, soluble ligand activity|coreceptor, insoluble ligand activity										GO:0015028|GO:0015027			molecular_function											owl:Class	
GO:0038023	biolink:NamedThing	signaling receptor activity	Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.	got7fsn_ti	receptor activity|signalling receptor activity|receptor activity involved in signal transduction						bf	2011-08-01T02:45:27Z			GO:0019041|GO:0004872			molecular_function											owl:Class	
GO:0042318	biolink:NamedThing	penicillin biosynthetic process	The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti	penicillin formation|penicillin anabolism|penicillin biosynthesis|penicillin synthesis													biological_process											owl:Class	
GO:0044629	biolink:NamedThing	negative regulation of complement activation, classical pathway in other organism	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism.	got7fsn_ti							jl	2012-07-05T01:03:25Z						biological_process											owl:Class	
GO:0045959	biolink:NamedThing	negative regulation of complement activation, classical pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.	got7fsn_ti	inhibition of complement activation, classical pathway|negative regulation of complement cascade, classical pathway|downregulation of complement activation, classical pathway|down regulation of complement activation, classical pathway|down-regulation of complement activation, classical pathway													biological_process											owl:Class	
GO:0048933	biolink:NamedThing	afferent axon development in posterior lateral line nerve	The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0048893	biolink:NamedThing	afferent axon development in lateral line nerve	The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0004379	biolink:NamedThing	glycylpeptide N-tetradecanoyltransferase activity	Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide.	got7fsn_ti	N-myristoyltransferase activity|protein N-myristoyltransferase activity|peptide N-tetradecanoyltransferase activity|myristoyl-CoA-protein N-myristoyltransferase activity|tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase activity|myristoylating enzymes|peptide N-myristoyltransferase activity|myristoyl-coenzyme A:protein N-myristoyl transferase activity										GO:0019106	Reactome:R-HSA-184392|Reactome:R-HSA-2534087|MetaCyc:2.3.1.97-RXN|RHEA:15521|EC:2.3.1.97		molecular_function											owl:Class	
GO:0016410	biolink:NamedThing	N-acyltransferase activity	Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule.	got7fsn_ti												Reactome:R-HSA-177160		molecular_function											owl:Class	
GO:0000920	biolink:NamedThing	septum digestion after cytokinesis	The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.	got7fsn_ti	mitotic cytokinetic cell separation|cell separation following cytokinesis|cytokinetic cell separation|daughter cell separation|cell separation after cytokinesis				This term should not be used to describe the last step of cytokinesis in organisms without a cell wall, ie, the cell resealing of the plasma membrane via abscission. Consider annotating to 'GO:0061952 midbody abscission' to capture this process.						GO:1902409|GO:2000695			biological_process											owl:Class	
GO:0009987	biolink:NamedThing	cellular process	Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	got7fsn_ti	cell growth and/or maintenance|single-organism cellular process|cellular physiological process|cell physiology						jl	2012-12-11T16:56:55Z			GO:0044763|GO:0050875|GO:0008151			biological_process											owl:Class	
GO:0070004	biolink:NamedThing	cysteine-type exopeptidase activity	Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	got7fsn_ti														molecular_function											owl:Class	
GO:0008238	biolink:NamedThing	exopeptidase activity	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.	got7fsn_ti	exoprotease activity													molecular_function											owl:Class	
GO:0071170	biolink:NamedThing	site-specific DNA replication termination	A DNA replication termination process that takes place at a specific termination site.	got7fsn_ti					See also the biological process term 'replication fork arrest ; GO:0043111' and its children.		mah	2009-11-20T01:07:30Z						biological_process											owl:Class	
GO:0006274	biolink:NamedThing	DNA replication termination	The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet.	got7fsn_ti														biological_process											owl:Class	
GO:0034321	biolink:NamedThing	alcohol O-octanoyltransferase activity	Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester.	got7fsn_ti														molecular_function											owl:Class	
GO:0016413	biolink:NamedThing	O-acetyltransferase activity	Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0051263	biolink:NamedThing	microcin E492 biosynthetic process by siderophore ester modification of peptidyl-serine	The modification of serine to N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine as found in microcin E492 produced from the mceA gene in plasmid pJAM229 of the E. coli VCS257 strain and the K. pneumoniae RYC492 strain.	got7fsn_ti	microcin E492 synthesis by siderophore ester modification of peptidyl-serine|microcin E492 anabolism by siderophore ester modification of peptidyl-serine|microcin E492 formation by siderophore ester modification of peptidyl-serine											RESID:AA0374		biological_process											owl:Class	
GO:0018209	biolink:NamedThing	peptidyl-serine modification	The modification of peptidyl-serine.	got7fsn_ti														biological_process											owl:Class	
GO:0047791	biolink:NamedThing	cucurbitacin delta23-reductase activity	Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+.	got7fsn_ti	cucurbitacin D23-reductase activity|NAD(P)H: cucurbitacin B delta23-oxidoreductase activity|23,24-dihydrocucurbitacin:NAD(P)+ delta23-oxidoreductase activity|cucurbitacin delta(23) reductase activity											EC:1.3.1.5|MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0016628	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.	got7fsn_ti												Reactome:R-HSA-9661745|Reactome:R-HSA-4419979|EC:1.3.1.-|Reactome:R-HSA-9661726|Reactome:R-HSA-4755572		molecular_function											owl:Class	
GO:0102616	biolink:NamedThing	oryzalexin A synthase activity	Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin A + H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-15464		molecular_function											owl:Class	
GO:0021819	biolink:NamedThing	layer formation in cerebral cortex	The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex.	got7fsn_ti	cerebral cortex lamination													biological_process											owl:Class	
GO:0048646	biolink:NamedThing	anatomical structure formation involved in morphogenesis	The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	got7fsn_ti	formation of an anatomical structure involved in morphogenesis				Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense.									biological_process											owl:Class	
GO:0001306	biolink:NamedThing	age-dependent response to oxidative stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism.	got7fsn_ti														biological_process											owl:Class	
GO:0006979	biolink:NamedThing	response to oxidative stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	got7fsn_ti														biological_process											owl:Class	
GO:0050261	biolink:NamedThing	ribose isomerase activity	Catalysis of the reaction: ribofuranose = D-ribulose.	got7fsn_ti	D-ribose isomerase activity|D-ribose ketol-isomerase activity|D-ribose aldose-ketose-isomerase activity											MetaCyc:RIBOSE-ISOMERASE-RXN|KEGG_REACTION:R01081|RHEA:20796|EC:5.3.1.20		molecular_function											owl:Class	
GO:0016861	biolink:NamedThing	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears.	got7fsn_ti	intramolecular isomerase activity, interconverting aldoses and ketoses											EC:5.3.1.-		molecular_function											owl:Class	
GO:1990756	biolink:NamedThing	ubiquitin ligase-substrate adaptor activity	The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.	got7fsn_ti	protein binding, bridging involved in substrate recognition for ubiquitination|ubiquitin ligase substrate adaptor	https://github.com/geneontology/go-ontology/issues/18655					vw	2015-06-01T08:35:16Z						molecular_function											owl:Class	
GO:0030674	biolink:NamedThing	protein-macromolecule adaptor activity	The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.	got7fsn_ti	protein binding, bridging|protein-protein adaptor	https://github.com/geneontology/go-ontology/issues/19409|https://github.com/geneontology/go-ontology/issues/18655												molecular_function											owl:Class	
GO:0004990	biolink:NamedThing	oxytocin receptor activity	Combining with oxytocin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0008528	biolink:NamedThing	G protein-coupled peptide receptor activity	Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	peptide receptor activity, G protein coupled|peptide receptor activity, G-protein coupled|G-protein coupled peptide receptor activity|G protein coupled peptide receptor activity													molecular_function											owl:Class	
GO:0140317	biolink:NamedThing	export across cell outer membrane	The directed movement of a substance across the outer membrane in cells with two membranes.	got7fsn_ti							pg	2019-04-01T08:12:23Z						biological_process											owl:Class	
GO:0055085	biolink:NamedThing	transmembrane transport	The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	membrane transport|ATP hydrolysis coupled transmembrane transport				Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes.		tb	2015-10-21T13:22:47Z			GO:0090662			biological_process											owl:Class	
GO:0072559	biolink:NamedThing	NLRP3 inflammasome complex	An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus.	got7fsn_ti	NALP3 inflammasome complex						mah	2011-01-27T12:04:30Z						cellular_component											owl:Class	
GO:0043761	biolink:NamedThing	archaetidylserine synthase activity	Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP.	got7fsn_ti	CDP-2,3-di-O-geranylgeranyl-sn-glycerol inositol 1-archaetidyltransferase activity|CDP-2,3-di-O-geranylgeranyl-sn-glycerol:l-serine O-archaetidyltransferase activity											EC:2.7.8.38		molecular_function											owl:Class	
GO:0016780	biolink:NamedThing	phosphotransferase activity, for other substituted phosphate groups	Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).	got7fsn_ti												Reactome:R-HSA-162742|Reactome:R-HSA-163069|EC:2.7.8.-		molecular_function											owl:Class	
GO:0000783	biolink:NamedThing	nuclear telomere cap complex	A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome.	got7fsn_ti					Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome.									cellular_component											owl:Class	
GO:0000782	biolink:NamedThing	telomere cap complex	A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome.	got7fsn_ti					Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome.									cellular_component											owl:Class	
GO:0102657	biolink:NamedThing	1-18:1-2-16:0-monogalactosyldiacylglycerol palmitoyl-lipid 7-desaturase activity	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.42|MetaCyc:RXN-1728		molecular_function											owl:Class	
GO:0016717	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.	got7fsn_ti												EC:1.14.19.-		molecular_function											owl:Class	
GO:0048733	biolink:NamedThing	sebaceous gland development	The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0048732	biolink:NamedThing	gland development	The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0035185	biolink:NamedThing	preblastoderm mitotic cell cycle	The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.	got7fsn_ti														biological_process											owl:Class	
GO:0045448	biolink:NamedThing	mitotic cell cycle, embryonic	The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0103057	biolink:NamedThing	gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A19 + O2 + 2-oxoglutarate <=> H+ + gibberellin A20 + 2 carbon dioxide + succinate.	got7fsn_ti												MetaCyc:RXN1F-169		molecular_function											owl:Class	
GO:0016706	biolink:NamedThing	2-oxoglutarate-dependent dioxygenase activity	Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.	got7fsn_ti	2-oxoglutarate dioxygenase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors										GO:0010302	Reactome:R-HSA-1234164|Reactome:R-HSA-6783455|EC:1.14.11.-		molecular_function											owl:Class	
GO:0036450	biolink:NamedThing	polyuridylation-dependent decapping of nuclear-transcribed mRNA	Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end.	got7fsn_ti	uridylation-dependent decapping of nuclear-transcribed mRNA						bf	2013-11-04T11:37:28Z						biological_process											owl:Class	
GO:0031087	biolink:NamedThing	deadenylation-independent decapping of nuclear-transcribed mRNA	Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.	got7fsn_ti	deadenylation-independent decapping of nuclear mRNA|deadenylylation-independent decapping													biological_process											owl:Class	
GO:0022406	biolink:NamedThing	membrane docking	The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.	got7fsn_ti	membrane docking													biological_process											owl:Class	
GO:0003332	biolink:NamedThing	negative regulation of extracellular matrix constituent secretion	Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.	got7fsn_ti							dph	2009-11-02T02:13:49Z						biological_process											owl:Class	
GO:1903054	biolink:NamedThing	negative regulation of extracellular matrix organization	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.	got7fsn_ti	downregulation of extracellular matrix organisation|downregulation of extracellular matrix organization|down regulation of extracellular matrix organization|downregulation of extracellular matrix organization and biogenesis|down regulation of extracellular matrix organisation|down regulation of extracellular matrix organization and biogenesis|inhibition of extracellular matrix organization and biogenesis|inhibition of extracellular matrix organisation|negative regulation of extracellular matrix organization and biogenesis|negative regulation of extracellular matrix organisation|down-regulation of extracellular matrix organisation|down-regulation of extracellular matrix organization|inhibition of extracellular matrix organization|down-regulation of extracellular matrix organization and biogenesis						rl	2014-05-23T17:15:47Z						biological_process											owl:Class	
GO:0015474	biolink:NamedThing	autotransporter activity	Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively.	got7fsn_ti														molecular_function											owl:Class	
GO:0015288	biolink:NamedThing	porin activity	Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	got7fsn_ti	porin|outer membrane exporter porin											Wikipedia:Porin_(protein)		molecular_function											owl:Class	
GO:0018546	biolink:NamedThing	nitrobenzene nitroreductase activity	Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O.	got7fsn_ti												MetaCyc:RXN-8815|RHEA:52884|UM-BBD_enzymeID:e0245		molecular_function											owl:Class	
GO:0016657	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.	got7fsn_ti	oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor											EC:1.6.6.-		molecular_function											owl:Class	
GO:0002301	biolink:NamedThing	CD4-positive, alpha-beta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	got7fsn_ti	CD4-positive, alpha-beta intraepithelial T-cell differentiation|CD4-positive, alpha-beta intraepithelial T-lymphocyte differentiation|CD4-positive, alpha-beta intraepithelial T cell development|CD4-positive, alpha-beta intraepithelial T lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0044468	biolink:NamedThing	envenomation resulting in modulation of blood coagulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism.	got7fsn_ti	envenomation resulting in regulation of blood coagulation in other organism						jl	2012-01-19T01:24:10Z						biological_process											owl:Class	
GO:0035738	biolink:NamedThing	envenomation resulting in modulation of process in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism.	got7fsn_ti	envenomation resulting in modification of morphology or physiology of other organism	https://github.com/geneontology/go-ontology/issues/18605					bf	2011-03-17T10:59:27Z						biological_process											owl:Class	
GO:0007019	biolink:NamedThing	microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of a microtubule.	got7fsn_ti	microtubule depolymerization during nuclear congression|microtubule catastrophe|microtubule shortening|microtubule disassembly													biological_process											owl:Class	
GO:0031109	biolink:NamedThing	microtubule polymerization or depolymerization	Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.	got7fsn_ti														biological_process											owl:Class	
GO:0035615	biolink:NamedThing	clathrin adaptor activity	Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles.	got7fsn_ti	clathrin-associated adaptor activity						bf	2010-12-01T11:17:57Z						molecular_function											owl:Class	
GO:0140312	biolink:NamedThing	cargo adaptor activity	Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo receptor, and membrane deformation machinery.	got7fsn_ti	endocytic adaptor activity	https://github.com/geneontology/go-ontology/issues/19454|https://github.com/geneontology/go-ontology/issues/17553					pg	2019-03-26T17:01:45Z			GO:0098748			molecular_function											owl:Class	
GO:0061049	biolink:NamedThing	cell growth involved in cardiac muscle cell development	The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.	got7fsn_ti	cardiomyocyte growth|heart muscle cell growth|cardiac muscle cell hypertrophy						dph	2010-02-25T12:56:07Z						biological_process											owl:Class	
GO:0048588	biolink:NamedThing	developmental cell growth	The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.	got7fsn_ti	developmental growth of a unicellular organism													biological_process											owl:Class	
GO:0044174	biolink:NamedThing	host cell endosome	A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.	got7fsn_ti	host endosome						jl	2009-09-04T03:02:01Z						cellular_component											owl:Class	
GO:0033648	biolink:NamedThing	host intracellular membrane-bounded organelle	Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	host intracellular membrane-enclosed organelle													cellular_component											owl:Class	
GO:0060364	biolink:NamedThing	frontal suture morphogenesis	The process in which the frontal suture is generated and organized.	got7fsn_ti	interfrontal suture morphogenesis													biological_process											owl:Class	
GO:0060363	biolink:NamedThing	cranial suture morphogenesis	The process in which any suture between cranial bones is generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0052792	biolink:NamedThing	endo-xylogalacturonan hydrolase activity	Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position.	got7fsn_ti	endo-galacturonase activity						ai	2011-10-05T03:57:30Z						molecular_function											owl:Class	
GO:0043426	biolink:NamedThing	MRF binding	Binding to Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.	got7fsn_ti	myogenin binding|Myf5 binding|MyoD binding|Mrf4 binding										GO:0051577|GO:0051579|GO:0051576|GO:0051578			molecular_function											owl:Class	
GO:0043425	biolink:NamedThing	bHLH transcription factor binding	Binding to a basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.	got7fsn_ti														molecular_function											owl:Class	
GO:0048160	biolink:NamedThing	primary follicle stage	The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.	got7fsn_ti	mammalian oogenesis stage 3													biological_process											owl:Class	
GO:0022605	biolink:NamedThing	mammalian oogenesis stage	A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell.	got7fsn_ti	mammalian oogenesis process													biological_process											owl:Class	
GO:0034746	biolink:NamedThing	APC-IQGAP1-CLIP-170 complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration.	got7fsn_ti					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0050021	biolink:NamedThing	L-arabinonolactonase activity	Catalysis of the reaction: L-arabinono-1,4-lactone + H(2)O = L-arabinonate + H(+).	got7fsn_ti	L-arabinono-1,4-lactone lactonohydrolase activity											EC:3.1.1.15|RHEA:16217|MetaCyc:L-ARABINONOLACTONASE-RXN|KEGG_REACTION:R02526		molecular_function											owl:Class	
GO:0052689	biolink:NamedThing	carboxylic ester hydrolase activity	Catalysis of the hydrolysis of a carboxylic ester bond.	got7fsn_ti	carboxylic acid esterase activity|vitamin A esterase|carboxyesterase activity|carboxylic esterase activity|carboxyl ester hydrolase activity|alpha-carboxylesterase activity|cocaine esterase activity|esterase B|procaine esterase activity|serine esterase activity|B-esterase activity|triacetin esterase|ali-esterase activity|carboxylate esterase activity|nonspecific carboxylesterase activity|carboxylesterase activity|carboxylic ester hydrolase activity|esterase A										GO:0004759|GO:0004302|GO:0016789|GO:0004091	UM-BBD_reactionID:r1025|RHEA:21164|Reactome:R-HSA-5693691|EC:3.1.1.1|KEGG_REACTION:R00630|MetaCyc:CARBOXYLESTERASE-RXN|Reactome:R-HSA-9619024|Reactome:R-HSA-8937442		molecular_function											owl:Class	
GO:0034640	biolink:NamedThing	establishment of mitochondrion localization by microtubule attachment	The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.	got7fsn_ti	mitochondrial localization by microtubule attachment|establishment of mitochondrion localisation by microtubule attachment|mitochondrial migration by microtubule attachment|mitochondrion migration by microtubule attachment													biological_process											owl:Class	
GO:0034643	biolink:NamedThing	establishment of mitochondrion localization, microtubule-mediated	The directed movement of the mitochondrion to a specific location, by a process involving microtubules.	got7fsn_ti	establishment of mitochondrion localisation, microtubule-mediated|mitochondrial localization, microtubule-mediated|microtubule-mediated mitochondrion localization													biological_process											owl:Class	
GO:0002097	biolink:NamedThing	tRNA wobble base modification	The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified.	got7fsn_ti														biological_process											owl:Class	
GO:0006400	biolink:NamedThing	tRNA modification	The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti	tRNA editing				The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.						GO:0016549			biological_process											owl:Class	
GO:0050461	biolink:NamedThing	L-mimosine synthase activity	Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate.	got7fsn_ti	O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl)|O3-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity|3-O-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity|O(3)-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl) activity											EC:2.5.1.52|KEGG_REACTION:R04091|RHEA:12693|MetaCyc:RXN-7461		molecular_function											owl:Class	
GO:0016765	biolink:NamedThing	transferase activity, transferring alkyl or aryl (other than methyl) groups	Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring alkyl or aryl groups, other than methyl groups										GO:0016766	Reactome:R-HSA-4755545|EC:2.5.1.-|Reactome:R-HSA-6782893|Reactome:R-HSA-4419978		molecular_function											owl:Class	
GO:0000774	biolink:NamedThing	adenyl-nucleotide exchange factor activity	Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.	got7fsn_ti												Reactome:R-HSA-5252079		molecular_function											owl:Class	
GO:0060590	biolink:NamedThing	ATPase regulator activity	Binds to and modulates the activity of an ATP hydrolysis activity.	got7fsn_ti	ATP hydrolysis regulator activity	https://github.com/geneontology/go-ontology/issues/20955					dph	2009-05-08T02:49:24Z						molecular_function											owl:Class	
GO:0106166	biolink:NamedThing	spindle pole body-nuclear membrane anchor activity	The binding activity of a molecule that brings together a mitotic spindle pole body and the nuclear membrane, in order to maintain specific membrane location of the spindle pole body.	got7fsn_ti	spindle pole body nuclear membrane anchor activity|nuclear membrane-spindle pole body anchor activity	https://github.com/geneontology/go-ontology/issues/20606|https://github.com/geneontology/go-ontology/issues/19119					hjd	2019-01-18T15:57:42Z						molecular_function											owl:Class	
GO:0140475	biolink:NamedThing	spindle pole body anchor activity	The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way.	got7fsn_ti							pg	2020-06-23T15:54:56Z						molecular_function											owl:Class	
GO:0061421	biolink:NamedThing	positive regulation of transcription by oleic acid	Any process involving oleic acid that activates or increases the rate of transcription.	got7fsn_ti							dph	2012-01-25T10:11:39Z						biological_process											owl:Class	
GO:0045991	biolink:NamedThing	carbon catabolite activation of transcription	A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.	got7fsn_ti	positive regulation of transcription by carbon catabolites													biological_process											owl:Class	
GO:0019250	biolink:NamedThing	aerobic cobalamin biosynthetic process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen.	got7fsn_ti	aerobic cobalamin formation|cobalamin biosynthesis, aerobic|vitamin B12 biosynthetic process, aerobic|aerobic cobalamin anabolism|aerobic cobalamin biosynthesis|cobalamin biosynthetic process, aerobic|vitamin B12 biosynthesis, aerobic|aerobic vitamin B12 biosynthetic process|aerobic vitamin B12 biosynthesis|aerobic cobalamin synthesis											MetaCyc:P381-PWY		biological_process											owl:Class	
GO:0009236	biolink:NamedThing	cobalamin biosynthetic process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	got7fsn_ti	vitamin B12 biosynthesis|cobalamin biosynthesis|vitamin B12 biosynthetic process|cobalamin formation|cobalamin anabolism|cobalamin synthesis													biological_process											owl:Class	
GO:0000159	biolink:NamedThing	protein phosphatase type 2A complex	A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.	got7fsn_ti	PP2A-pi|protein phosphatase 2 complex|PP2a-protector|PP2A complex													cellular_component											owl:Class	
GO:0008287	biolink:NamedThing	protein serine/threonine phosphatase complex	A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.	got7fsn_ti														cellular_component											owl:Class	
GO:0102402	biolink:NamedThing	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity	Catalysis of the reaction: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside + H2O = 2-phenylethanol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose.	got7fsn_ti												MetaCyc:RXN-13694|EC:3.2.1.149		molecular_function											owl:Class	
GO:0017151	biolink:NamedThing	DEAD/H-box RNA helicase binding	Binding to a DEAD/H-box RNA helicase.	got7fsn_ti														molecular_function											owl:Class	
GO:0019899	biolink:NamedThing	enzyme binding	Binding to an enzyme, a protein with catalytic activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0052092	biolink:NamedThing	positive regulation by symbiont of nutrient release from host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	stimulation by symbiont of nutrient release from host|activation by symbiont of nutrient release from host|promotion of nutrient release from host|up-regulation by symbiont of nutrient release from host|upregulation by symbiont of nutrient release from host|up regulation by symbiont of nutrient release from host													biological_process											owl:Class	
GO:0052520	biolink:NamedThing	positive regulation by organism of nutrient release from other organism involved in symbiotic interaction	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of nutrient release from other organism during symbiotic interaction|promotion of nutrient release from other organism|stimulation by organism of nutrient release from other organism during symbiotic interaction|activation by organism of nutrient release from other organism during symbiotic interaction|upregulation by organism of nutrient release from other organism during symbiotic interaction|up-regulation by organism of nutrient release from other organism during symbiotic interaction|up regulation by organism of nutrient release from other organism during symbiotic interaction													biological_process											owl:Class	
GO:0047257	biolink:NamedThing	diglucosyl diacylglycerol synthase activity	Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol.	got7fsn_ti	DGlcDAG synthase activity|monoglucosyl diacylglycerol (1->2) glucosyltransferase activity|MGlcDAG (1->2) glucosyltransferase activity|UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase activity|diglucosyl diacylglycerol (DGlcDAG) synthase activity											MetaCyc:2.4.1.208-RXN|RHEA:19165|EC:2.4.1.208		molecular_function											owl:Class	
GO:0008194	biolink:NamedThing	UDP-glycosyltransferase activity	Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.	got7fsn_ti												Reactome:R-HSA-162730		molecular_function											owl:Class	
GO:0043259	biolink:NamedThing	laminin-10 complex	A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains.	got7fsn_ti	laminin-511 complex													cellular_component											owl:Class	
GO:0043256	biolink:NamedThing	laminin complex	A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes.	got7fsn_ti														cellular_component											owl:Class	
GO:1990447	biolink:NamedThing	U2 snRNP binding	Binding to a U2 small nuclear ribonucleoprotein particle.	got7fsn_ti							mah	2014-08-06T09:33:38Z						molecular_function											owl:Class	
GO:0070990	biolink:NamedThing	snRNP binding	Binding to a small nuclear ribonucleoprotein particle.	got7fsn_ti							mah	2009-10-29T03:54:25Z						molecular_function											owl:Class	
GO:0002261	biolink:NamedThing	mucosal lymphocyte homeostasis	The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0002260	biolink:NamedThing	lymphocyte homeostasis	The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0022881	biolink:NamedThing	protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	N-acetylgalactosamine PTS transporter activity													molecular_function											owl:Class	
GO:0008982	biolink:NamedThing	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	phosphotransferase, phosphohistidinoprotein-hexose activity|gene glC proteins|protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase activity|phosphotransfer-driven group translocator|gene bglC RNA formation factors|PTS permease activity|protein-Np-phosphohistidine-sugar phosphotransferase activity|protein-Npi-phosphohistidine:sugar N-pros-phosphotransferase activity|PTS transporter|phosphoenolpyruvate-sugar phosphotransferase enzyme II|sucrose phosphotransferase system II|protein-Npi-phospho-L-histidine:sugar N-pros-phosphotransferase activity|ribonucleic acid formation factor, gene glC|phosphoprotein factor-hexose phosophotransferase activity|group translocator activity|enzyme II of the phosphotransferase system|PEP-dependent phosphotransferase enzyme II|phosphohistidinoprotein-hexose phosphotransferase activity|protein-Npi-phosphohistidine-sugar phosphotransferase activity|phosphohistidinoprotein-hexose phosphoribosyltransferase activity|enzyme IIl4ac|PEP--sugar phosphotransferase enzyme II activity|protein, specific or class, gene bglC										GO:0015455|GO:0015456	MetaCyc:2.7.1.69-RXN|EC:2.7.1.69		molecular_function											owl:Class	
GO:1990147	biolink:NamedThing	talin binding	Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types.	got7fsn_ti							hjd	2013-07-25T19:49:53Z						molecular_function											owl:Class	
GO:0008092	biolink:NamedThing	cytoskeletal protein binding	Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).	got7fsn_ti														molecular_function											owl:Class	
GO:0004517	biolink:NamedThing	nitric-oxide synthase activity	Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.	got7fsn_ti	endothelium-derived relaxing factor synthase activity|NO synthase activity|nitric oxide synthetase activity|nitric-oxide synthetase activity|NADPH-diaphorase activity|nitric oxide synthase activity|L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity|endothelium-derived relaxation factor-forming enzyme activity											Reactome:R-HSA-418436|RHEA:19897|Reactome:R-HSA-202127|EC:1.14.13.39|MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0140060	biolink:NamedThing	axon arborization	The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches.	got7fsn_ti							pg	2017-07-12T15:17:22Z						biological_process											owl:Class	
GO:0007409	biolink:NamedThing	axonogenesis	De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.	got7fsn_ti	axon morphogenesis|neuron long process generation|axon growth				Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon).						GO:0007410			biological_process											owl:Class	
GO:0061778	biolink:NamedThing	intracellular chloride channel activity	Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	got7fsn_ti							dph	2016-08-02T09:37:15Z						molecular_function											owl:Class	
GO:0005254	biolink:NamedThing	chloride channel activity	Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti												Reactome:R-HSA-975340|Reactome:R-HSA-975449|Reactome:R-HSA-427570|Reactome:R-HSA-2744349		molecular_function											owl:Class	
GO:0046917	biolink:NamedThing	triphosphoribosyl-dephospho-CoA synthase activity	Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine.	got7fsn_ti	ATP:dephospho-CoA 5-triphosphoribosyl transferase activity|ATP:3-dephospho-CoA 5''-triphosphoribosyltransferase activity|CitG activity|2'-(5''-triphosphoribosyl)-3-dephospho-CoA synthase activity											EC:2.4.2.52|RHEA:15117|MetaCyc:2.7.8.25-RXN		molecular_function											owl:Class	
GO:0003222	biolink:NamedThing	ventricular trabecula myocardium morphogenesis	The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.	got7fsn_ti	trabecula carnea morphogenesis						dph	2009-10-13T10:33:00Z						biological_process											owl:Class	
GO:0061384	biolink:NamedThing	heart trabecula morphogenesis	The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.	got7fsn_ti							dph	2010-12-02T08:54:20Z						biological_process											owl:Class	
GO:0010196	biolink:NamedThing	nonphotochemical quenching	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.	got7fsn_ti														biological_process											owl:Class	
GO:1990066	biolink:NamedThing	energy quenching	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence.	got7fsn_ti							tb	2013-03-27T21:02:00Z						biological_process											owl:Class	
GO:0070669	biolink:NamedThing	response to interleukin-2	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.	got7fsn_ti	response to IL-2						mah	2009-05-29T09:59:43Z						biological_process											owl:Class	
GO:0034097	biolink:NamedThing	response to cytokine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.	got7fsn_ti	response to cytokine stimulus													biological_process											owl:Class	
GO:1990768	biolink:NamedThing	gastric mucosal blood circulation	The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.	got7fsn_ti	stomach mucosal blood circulation						sl	2015-06-10T20:11:09Z						biological_process											owl:Class	
GO:0008015	biolink:NamedThing	blood circulation	The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.	got7fsn_ti	hemolymph circulation										GO:0070261			biological_process											owl:Class	
GO:0048584	biolink:NamedThing	positive regulation of response to stimulus	Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.	got7fsn_ti	activation of response to stimulus|stimulation of response to stimulus|up-regulation of response to stimulus|up regulation of response to stimulus|upregulation of response to stimulus				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0048583	biolink:NamedThing	regulation of response to stimulus	Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0006081	biolink:NamedThing	cellular aldehyde metabolic process	The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.	got7fsn_ti	alkanal metabolic process|alkanal metabolism|aldehyde metabolism													biological_process											owl:Class	
GO:0050984	biolink:NamedThing	peptidyl-serine sulfation	The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine.	got7fsn_ti												RESID:AA0361		biological_process											owl:Class	
GO:0070857	biolink:NamedThing	regulation of bile acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.	got7fsn_ti	regulation of bile acid synthesis|regulation of bile acid biosynthesis|regulation of bile acid anabolism|regulation of bile acid formation						mah	2009-08-14T03:09:02Z						biological_process											owl:Class	
GO:0010565	biolink:NamedThing	regulation of cellular ketone metabolic process	Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.	got7fsn_ti														biological_process											owl:Class	
GO:0072297	biolink:NamedThing	specification of metanephric proximal tubule identity	The process in which the proximal tubule of the metanephric nephron acquires its identity.	got7fsn_ti							mah	2010-04-09T04:08:20Z						biological_process											owl:Class	
GO:0031031	biolink:NamedThing	positive regulation of septation initiation signaling	Any process that activates or increases the frequency, rate or extent of septation initiation signaling.	got7fsn_ti	upregulation of septation initiation signaling|stimulation of septation initiation signaling|positive regulation of septation initiation signalling|positive regulation of septation initiation signaling cascade|up regulation of septation initiation signaling|up-regulation of septation initiation signaling|positive regulation of septation initiation network|activation of septation initiation signaling													biological_process											owl:Class	
GO:0010973	biolink:NamedThing	positive regulation of division septum assembly	Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	got7fsn_ti	positive regulation of division septum formation|positive regulation of division septum formation involved in cell cycle cytokinesis|upregulation of mitotic division septum assembly						tb	2009-06-01T10:27:15Z			GO:1901912|GO:1902470			biological_process											owl:Class	
GO:0070091	biolink:NamedThing	glucagon secretion	The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).	got7fsn_ti														biological_process											owl:Class	
GO:0030072	biolink:NamedThing	peptide hormone secretion	The regulated release of a peptide hormone from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0043721	biolink:NamedThing	4-hydroxybutanoyl-CoA dehydratase activity	Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O.	got7fsn_ti	gamma-hydroxybutyryl-CoA dehydratase activity|4-hydroxybutanoyl-CoA hydro-lyase|4-hydroxybutyryl-CoA dehydratase activity|gamma-hydroxybutanoyl-CoA dehydratase activity											RHEA:26530|KEGG_REACTION:R05337|MetaCyc:RXN-8890|EC:4.2.1.120		molecular_function											owl:Class	
GO:0016836	biolink:NamedThing	hydro-lyase activity	Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.	got7fsn_ti												Reactome:R-HSA-9014627|EC:4.2.1.-		molecular_function											owl:Class	
GO:0060894	biolink:NamedThing	limb spinous cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti							dph	2009-08-13T01:46:23Z						biological_process											owl:Class	
GO:0009957	biolink:NamedThing	epidermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	hypodermal cell fate specification										GO:0043356			biological_process											owl:Class	
GO:0090729	biolink:NamedThing	toxin activity	Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.	got7fsn_ti	toxin receptor binding						tb	2016-12-19T15:23:27Z			GO:0050827	Wikipedia:Toxin		molecular_function											owl:Class	
GO:0003674	biolink:NamedThing	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.	got7fsn_ti	molecular function				Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.						GO:0005554			molecular_function											owl:Class	
GO:0007089	biolink:NamedThing	traversing start control point of mitotic cell cycle	A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.	got7fsn_ti											GO:0000081			biological_process											owl:Class	
GO:1900087	biolink:NamedThing	positive regulation of G1/S transition of mitotic cell cycle	Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.	got7fsn_ti	activation of G1/S transition of mitotic cell cycle|up regulation of G1/S transition of mitotic cell cycle|up-regulation of G1/S transition of mitotic cell cycle|upregulation of G1/S transition of mitotic cell cycle						rph	2012-02-08T12:24:39Z						biological_process											owl:Class	
GO:0035116	biolink:NamedThing	embryonic hindlimb morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.	got7fsn_ti														biological_process											owl:Class	
GO:0030326	biolink:NamedThing	embryonic limb morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.	got7fsn_ti														biological_process											owl:Class	
GO:0048462	biolink:NamedThing	carpel formation	The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti											GO:0048431			biological_process											owl:Class	
GO:0048449	biolink:NamedThing	floral organ formation	The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti											GO:0048436			biological_process											owl:Class	
GO:0003105	biolink:NamedThing	negative regulation of glomerular filtration	Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.	got7fsn_ti														biological_process											owl:Class	
GO:0051241	biolink:NamedThing	negative regulation of multicellular organismal process	Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.	got7fsn_ti	down regulation of multicellular organismal process|down-regulation of multicellular organismal process|downregulation of multicellular organismal process|inhibition of multicellular organismal process													biological_process											owl:Class	
GO:0061760	biolink:NamedThing	antifungal innate immune response	An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti							dph	2016-03-07T08:53:08Z						biological_process											owl:Class	
GO:0045087	biolink:NamedThing	innate immune response	Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti	nonspecific immune response|innate immunity										GO:0002226	Wikipedia:Innate_immune_system		biological_process											owl:Class	
GO:0019815	biolink:NamedThing	B cell receptor complex	An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	got7fsn_ti	B lymphocyte receptor complex|immunoglobulin complex, membrane bound|BCR complex|B-lymphocyte receptor complex|antibody|B-cell receptor complex|B cell receptor accessory molecule complex				Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.						GO:0042570			cellular_component											owl:Class	
GO:0043235	biolink:NamedThing	receptor complex	Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti														cellular_component											owl:Class	
GO:0004689	biolink:NamedThing	phosphorylase kinase activity	Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.	got7fsn_ti	dephosphophosphorylase kinase activity|phosphorylase kinase (phosphorylating) activity|phosphorylase B kinase activity|phosphorylase kinase, intrinsic catalyst activity|glycogen phosphorylase kinase activity|PHK|STK17|ATP:phosphorylase-b phosphotransferase activity										GO:0008606	Reactome:R-HSA-453337|Reactome:R-HSA-71541|Reactome:R-HSA-71588|MetaCyc:2.7.11.19-RXN|EC:2.7.11.19		molecular_function											owl:Class	
GO:0004683	biolink:NamedThing	calmodulin-dependent protein kinase activity	Calmodulin-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.	got7fsn_ti	multifunctional calcium- and calmodulin-regulated protein kinase activity|calcium- and calmodulin-dependent protein kinase activity|caldesmon kinase (phosphorylating) activity|CaMKKbeta|calcium/calmodulin-dependent protein kinase type II activity|calmodulin regulated protein kinase activity|CaM kinase II activity|calcium/calmodulin-dependent protein kinase activity|calmodulin-dependent protein kinase I activity|CaMKI|ATP:caldesmon O-phosphotransferase activity|multifunctional calcium/calmodulin regulated protein kinase activity|STK20|Ca2+/calmodulin-dependent protein kinase activity|Ca2+/calmodulin-dependent protein kinase IV activity|CAM PKII|CaMKKalpha|CaM-regulated serine/threonine kinase activity|CaM kinase activity|Ca2+/calmodulin-dependent protein kinase kinase beta activity|Ca2+/calmodulin-dependent protein kinase kinase activity|Ca2+/calmodulin-dependent protein kinase 1 activity|CaMKIV|CaMKII|calmodulin-dependent kinase II activity|Ca2+/CaM-dependent kinase activity|Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity|microtubule-associated protein 2 kinase activity|Ca2+/calmodulin-dependent protein kinase II activity|ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity				These reactions require the presence of calcium-bound calmodulin.						GO:0004685|GO:0004688|GO:0004684	Reactome:R-HSA-9619355|Reactome:R-HSA-9617583|Reactome:R-HSA-9619478|Reactome:R-HSA-9618750|Reactome:R-HSA-111912|Reactome:R-HSA-9619783|Reactome:R-HSA-111915|Reactome:R-HSA-9619367|MetaCyc:2.7.11.17-RXN|Reactome:R-HSA-416320|EC:2.7.11.17|Reactome:R-HSA-442749|Reactome:R-HSA-9006992|Reactome:R-HSA-9619125		molecular_function											owl:Class	
GO:0030050	biolink:NamedThing	vesicle transport along actin filament	Movement of a vesicle along an actin filament, mediated by motor proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0030048	biolink:NamedThing	actin filament-based movement	Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0097506	biolink:NamedThing	deaminated base DNA N-glycosylase activity	DNA N-glycosylase activity acting on deaminated bases.	got7fsn_ti	DNA glycosylase activity acting on deaminated bases|deaminated base DNA glycosylase activity						pr	2013-09-26T16:00:40Z						molecular_function											owl:Class	
GO:0019104	biolink:NamedThing	DNA N-glycosylase activity	Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.	got7fsn_ti	endonuclease VIII activity|DNA glycosylase activity										GO:0008578	Reactome:R-HSA-9629149|Reactome:R-HSA-9636008|Reactome:R-HSA-110250|Reactome:R-HSA-110231|Reactome:R-HSA-5220959|Reactome:R-HSA-110234|Reactome:R-HSA-5649673|Reactome:R-HSA-110246|Reactome:R-HSA-9629497|Reactome:R-HSA-9635996|Reactome:R-HSA-110219|Reactome:R-HSA-110218|Reactome:R-HSA-110251|Reactome:R-HSA-9629483|Reactome:R-HSA-9629492|Reactome:R-HSA-110232|Reactome:R-HSA-5649664|Reactome:R-HSA-5649658|Reactome:R-HSA-5221061|Reactome:R-HSA-9629499|Reactome:R-HSA-9629470|Reactome:R-HSA-110248|Reactome:R-HSA-5649681|Reactome:R-HSA-9629216		molecular_function											owl:Class	
GO:0061269	biolink:NamedThing	mesonephric glomerular mesangial cell proliferation involved in mesonephros development	The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population.	got7fsn_ti							dph	2010-08-30T03:20:57Z						biological_process											owl:Class	
GO:0061209	biolink:NamedThing	cell proliferation involved in mesonephros development	The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.	got7fsn_ti							dph	2010-08-17T03:22:46Z						biological_process											owl:Class	
GO:0047798	biolink:NamedThing	cyclomaltodextrinase activity	Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin.	got7fsn_ti	cyclohexaglucanase activity|cyclodextrinase activity|cyclomaltodextrin dextrin-hydrolase (decyclizing)|cycloheptaglucanase activity											MetaCyc:CYCLOMALTODEXTRINASE-RXN|RHEA:23980|EC:3.2.1.54		molecular_function											owl:Class	
GO:0034358	biolink:NamedThing	plasma lipoprotein particle	A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.	got7fsn_ti														cellular_component											owl:Class	
GO:1990777	biolink:NamedThing	lipoprotein particle	A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph.	got7fsn_ti							pr	2015-06-18T08:42:53Z						cellular_component											owl:Class	
GO:1990416	biolink:NamedThing	cellular response to brain-derived neurotrophic factor stimulus	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus.	got7fsn_ti	cellular response to BDNF stimulus						sl	2014-07-11T17:55:59Z						biological_process											owl:Class	
GO:1990090	biolink:NamedThing	cellular response to nerve growth factor stimulus	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.	got7fsn_ti	cellular response to NGF						sl	2013-05-06T17:13:36Z						biological_process											owl:Class	
GO:0006346	biolink:NamedThing	DNA methylation-dependent heterochromatin assembly	Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.	got7fsn_ti	methylation-dependent heterochromatic silencing|methylation-dependent chromatin silencing	https://github.com/geneontology/go-ontology/issues/22047												biological_process											owl:Class	
GO:0031507	biolink:NamedThing	heterochromatin assembly	An epigenetic gene silencing mechanism that involves the assembly of chromatin into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.	got7fsn_ti	establishment of heterochromatin architecture|chromatin-mediated silencing|establishment of heterochromatin architecture involved in chromatin silencing at pericentric region|establishment of chromatin silencing|establishment of heterochromatic silencing|heterochromatin formation|heterochromatin formation involved in chromatin silencing|chromatin silencing|TGS|heterochromatic silencing|heterochromatin assembly involved in chromatin silencing|heterochromatin assembly involved in chromatin silencing at pericentric region|transcriptional gene silencing|establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region|heterochromatin maintenance|heterochromatin formation involved in chromatin silencing at centromere outer repeat region|heterochromatin assembly involved in chromatin silencing at centromere outer repeat region|heterochromatin formation involved in chromatin silencing at pericentric region	https://github.com/geneontology/go-ontology/issues/18954|https://github.com/geneontology/go-ontology/issues/22030|https://github.com/geneontology/go-ontology/issues/19112									GO:0006343|GO:1904497|GO:0016440|GO:0070869|GO:0006342			biological_process											owl:Class	
GO:0046666	biolink:NamedThing	retinal cell programmed cell death	Programmed cell death that occurs in the developing retina.	got7fsn_ti	retina programmed cell death|retina cell programmed cell death|retinal programmed cell death|programmed cell death, retinal cells|programmed cell death, retina cells													biological_process											owl:Class	
GO:0098834	biolink:NamedThing	presynaptic endocytic zone cytoplasmic component	The cytoplasmic component of the presynaptic endocytic zone.	got7fsn_ti	cortex of presynaptic endocytic zone													cellular_component											owl:Class	
GO:0099738	biolink:NamedThing	cell cortex region	The complete extent of cell cortex that underlies some some region of the plasma membrane.	got7fsn_ti	perimembrane region													cellular_component											owl:Class	
GO:0102538	biolink:NamedThing	UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-14767		molecular_function											owl:Class	
GO:0016623	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.	got7fsn_ti												EC:1.2.3.-		molecular_function											owl:Class	
GO:0016903	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors											EC:1.2.-.-		molecular_function											owl:Class	
GO:0075512	biolink:NamedThing	clathrin-dependent endocytosis of virus by host cell	Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.	got7fsn_ti	viral entry into host cell via clathrin-mediated endocytosis|viral entry into host cell via clathrin-mediated endocytosis followed by endosome lysis|viral penetration via clathrin-mediated endocytosis|clathrin-mediated endocytosis of virus by host cell						jl	2011-07-27T02:08:54Z			GO:0075516	VZ:957		biological_process											owl:Class	
GO:0072583	biolink:NamedThing	clathrin-dependent endocytosis	An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.	got7fsn_ti	clathrin-mediated endocytosis|clathrin-dependent endocytosis|clathrin coated pit-dependent endocytosis|CME						mah	2011-02-08T03:59:18Z						biological_process											owl:Class	
GO:0060455	biolink:NamedThing	negative regulation of gastric acid secretion	Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.	got7fsn_ti														biological_process											owl:Class	
GO:0060453	biolink:NamedThing	regulation of gastric acid secretion	Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.	got7fsn_ti														biological_process											owl:Class	
GO:0021592	biolink:NamedThing	fourth ventricle development	The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.	got7fsn_ti														biological_process											owl:Class	
GO:0044108	biolink:NamedThing	cellular alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, carried out at the level of an individual cell.	got7fsn_ti							jl	2009-07-15T01:38:25Z						biological_process											owl:Class	
GO:0044249	biolink:NamedThing	cellular biosynthetic process	The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.	got7fsn_ti	cellular formation|cellular synthesis|cellular biosynthesis|cellular anabolism													biological_process											owl:Class	
GO:0048936	biolink:NamedThing	peripheral nervous system neuron axonogenesis	Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.	got7fsn_ti														biological_process											owl:Class	
GO:0042465	biolink:NamedThing	kinesis	The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus.	got7fsn_ti												Wikipedia:Kinesis		biological_process											owl:Class	
GO:0009605	biolink:NamedThing	response to external stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.	got7fsn_ti	response to environmental stimulus				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0048639	biolink:NamedThing	positive regulation of developmental growth	Any process that activates, maintains or increases the rate of developmental growth.	got7fsn_ti	up-regulation of developmental growth|activation of developmental growth|upregulation of developmental growth|stimulation of developmental growth|up regulation of developmental growth													biological_process											owl:Class	
GO:0045927	biolink:NamedThing	positive regulation of growth	Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.	got7fsn_ti	stimulation of growth|upregulation of growth|up-regulation of growth|up regulation of growth|activation of growth													biological_process											owl:Class	
GO:0045210	biolink:NamedThing	FasL biosynthetic process	The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines.	got7fsn_ti	FASLG biosynthetic process|FasL formation|CD95L biosynthetic process|APT1LG1 biosynthetic process|CD178 biosynthetic process|FasL synthesis|fas ligand biosynthetic process|CD95L biosynthesis|FasL anabolism|Fas-L biosynthetic process|FasL biosynthesis													biological_process											owl:Class	
GO:0009101	biolink:NamedThing	glycoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	got7fsn_ti	glycoprotein biosynthesis|glycoprotein anabolism|glycoprotein synthesis|glycoprotein formation													biological_process											owl:Class	
GO:0014010	biolink:NamedThing	Schwann cell proliferation	The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0014009	biolink:NamedThing	glial cell proliferation	The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.	got7fsn_ti	glia proliferation													biological_process											owl:Class	
GO:0050742	biolink:NamedThing	protein-FMN linkage via S-(4a-FMN)-L-cysteine	The formation of a protein-FMN linkage via S-(4a-FMN)-L-cysteine.	got7fsn_ti												RESID:AA0351		biological_process											owl:Class	
GO:0018309	biolink:NamedThing	protein-FMN linkage	The formation of a linkage between a protein amino acid and flavin mononucleotide (FMN).	got7fsn_ti														biological_process											owl:Class	
GO:0047224	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP.	got7fsn_ti	uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase activity|core 3-beta-GlcNAc-transferase activity|mucin core 3 beta3-GlcNAc-transferase activity|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity|core 3beta-GlcNAc-transferase activity											EC:2.4.1.147|RHEA:14252|MetaCyc:2.4.1.147-RXN		molecular_function											owl:Class	
GO:0008375	biolink:NamedThing	acetylglucosaminyltransferase activity	Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar.	got7fsn_ti	GlcNAc transferase activity											Reactome:R-HSA-9694656|Reactome:R-HSA-9683648|Reactome:R-HSA-5694487|Reactome:R-HSA-8879117		molecular_function											owl:Class	
GO:0061241	biolink:NamedThing	mesonephric nephron epithelium development	The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.	got7fsn_ti							dph	2010-08-19T03:11:59Z						biological_process											owl:Class	
GO:0072009	biolink:NamedThing	nephron epithelium development	The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.	got7fsn_ti							mah	2010-01-25T02:01:39Z						biological_process											owl:Class	
GO:0047041	biolink:NamedThing	(S)-carnitine 3-dehydrogenase activity	Catalysis of the reaction: (S)-carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH.	got7fsn_ti	(S)-carnitine:NAD+ oxidoreductase activity|D-carnitine dehydrogenase activity											KEGG_REACTION:R01921|RHEA:11556|EC:1.1.1.254|MetaCyc:1.1.1.254-RXN		molecular_function											owl:Class	
GO:0035186	biolink:NamedThing	syncytial blastoderm mitotic cell cycle	Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.	got7fsn_ti														biological_process											owl:Class	
GO:0033301	biolink:NamedThing	cell cycle comprising mitosis without cytokinesis	A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).	got7fsn_ti					Note that this term should be used for naturally occurring instances of mitosis without cytokinesis, e.g. in the tapetum of flowers and in a number of lower eukaryotes; it should not be used for abnormal events such as may occur in cancers.									biological_process											owl:Class	
GO:0008380	biolink:NamedThing	RNA splicing	The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.	got7fsn_ti	pre-mRNA splicing factor activity										GO:0006395	Wikipedia:RNA_splicing		biological_process											owl:Class	
GO:0006396	biolink:NamedThing	RNA processing	Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.	got7fsn_ti											GO:0006394	Wikipedia:Post-transcriptional_modification		biological_process											owl:Class	
GO:0099018	biolink:NamedThing	restriction-modification system evasion by virus	Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction.	got7fsn_ti												VZ:3966		biological_process											owl:Class	
GO:0019049	biolink:NamedThing	mitigation of host defenses by virus	A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	evasion of host defenses by virus|viral host defence evasion|evasion or tolerance of host defenses by virus|viral host defense evasion													biological_process											owl:Class	
GO:0090492	biolink:NamedThing	N,N-Dihydroxy-L-tryptophan decarboxylase activity	Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O.	got7fsn_ti							tb	2012-10-16T16:32:30Z						molecular_function											owl:Class	
GO:0016831	biolink:NamedThing	carboxy-lyase activity	Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.	got7fsn_ti	decarboxylase activity											EC:4.1.1.-|Reactome:R-HSA-6814165|Reactome:R-HSA-6787757|Reactome:R-HSA-71223		molecular_function											owl:Class	
GO:0047437	biolink:NamedThing	4-oxalocrotonate decarboxylase activity	Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate.	got7fsn_ti	4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming)|4-oxalocrotonate carboxy-lyase activity											MetaCyc:4.1.1.77-RXN|UM-BBD_reactionID:r1435|RHEA:24260|EC:4.1.1.77		molecular_function											owl:Class	
GO:0002696	biolink:NamedThing	positive regulation of leukocyte activation	Any process that activates or increases the frequency, rate, or extent of leukocyte activation.	got7fsn_ti	positive regulation of leucocyte activation|upregulation of leukocyte activation|stimulation of leukocyte activation|activation of leukocyte activation|up regulation of leukocyte activation|up-regulation of leukocyte activation|positive regulation of immune cell activation													biological_process											owl:Class	
GO:0050867	biolink:NamedThing	positive regulation of cell activation	Any process that activates or increases the frequency, rate or extent of activation.	got7fsn_ti	activation of cell activation|stimulation of cell activation|up regulation of cell activation|upregulation of cell activation|up-regulation of cell activation													biological_process											owl:Class	
GO:0021821	biolink:NamedThing	negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination	The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.	got7fsn_ti	down regulation of cell-glial cell adhesion involved in cerebral cortex lamination|down-regulation of cell-glial cell adhesion involved in cerebral cortex lamination|downregulation of cell-glial cell adhesion involved in cerebral cortex lamination|inhibition of cell-glial cell adhesion involved in cerebral cortex lamination													biological_process											owl:Class	
GO:0022408	biolink:NamedThing	negative regulation of cell-cell adhesion	Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.	got7fsn_ti	down-regulation of cell-cell adhesion|downregulation of cell-cell adhesion|down regulation of cell-cell adhesion|inhibition of cell-cell adhesion													biological_process											owl:Class	
GO:0022894	biolink:NamedThing	Intermediate conductance calcium-activated potassium channel activity	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	got7fsn_ti	IK KCa channels|IK calcium-activated potassium channel activity|intermdiate conductance KCa channels													molecular_function											owl:Class	
GO:0015269	biolink:NamedThing	calcium-activated potassium channel activity	Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.	got7fsn_ti														molecular_function											owl:Class	
GO:0034524	biolink:NamedThing	2-hydroxyisophthalate decarboxylase activity	Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2.	got7fsn_ti												UM-BBD_reactionID:r0776		molecular_function											owl:Class	
GO:0007008	biolink:NamedThing	outer mitochondrial membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane.	got7fsn_ti	outer mitochondrial membrane organisation|outer mitochondrial membrane organization and biogenesis				See also the cellular component term 'mitochondrial outer membrane ; GO:0005741'.									biological_process											owl:Class	
GO:0007006	biolink:NamedThing	mitochondrial membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.	got7fsn_ti	mitochondrial membrane organisation|mitochondrial membrane organization and biogenesis													biological_process											owl:Class	
GO:0044648	biolink:NamedThing	histone H3-K4 dimethylation	The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone.	got7fsn_ti							jl	2012-07-11T01:27:33Z						biological_process											owl:Class	
GO:0051568	biolink:NamedThing	histone H3-K4 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.	got7fsn_ti	histone H3 K4 methylation|histone H3K4me|histone lysine H3 K4 methylation													biological_process											owl:Class	
GO:0035678	biolink:NamedThing	neuromast hair cell morphogenesis	The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.	got7fsn_ti							bf	2011-02-14T11:06:15Z						biological_process											owl:Class	
GO:0048667	biolink:NamedThing	cell morphogenesis involved in neuron differentiation	The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.	got7fsn_ti	neuron morphogenesis involved in differentiation													biological_process											owl:Class	
GO:0075113	biolink:NamedThing	induction by symbiont of host transmembrane receptor-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host transmembrane receptor-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075082".									biological_process											owl:Class	
GO:0075110	biolink:NamedThing	induction by symbiont of host receptor-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host receptor-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont receptor-mediated signal transduction ; GO:0075079".									biological_process											owl:Class	
GO:1900611	biolink:NamedThing	F-9775A biosynthetic process	The chemical reactions and pathways resulting in the formation of F-9775A.	got7fsn_ti	F-9775A anabolism|F-9775A synthesis|F-9775A biosynthesis|F-9775A formation						di	2012-05-15T07:02:56Z						biological_process											owl:Class	
GO:0009719	biolink:NamedThing	response to endogenous stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0050896	biolink:NamedThing	response to stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.	got7fsn_ti	physiological response to stimulus				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.						GO:0051869			biological_process											owl:Class	
GO:0098505	biolink:NamedThing	G-rich strand telomeric DNA binding	Binding to G-rich, single-stranded, telomere-associated DNA.	got7fsn_ti							dos	2013-09-23T13:16:24Z						molecular_function											owl:Class	
GO:0043047	biolink:NamedThing	single-stranded telomeric DNA binding	Binding to single-stranded telomere-associated DNA.	got7fsn_ti	telomeric ssDNA binding													molecular_function											owl:Class	
GO:0035284	biolink:NamedThing	brain segmentation	Division of the brain into a series of semi-repetitive parts or segments.	got7fsn_ti														biological_process											owl:Class	
GO:0035282	biolink:NamedThing	segmentation	The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.	got7fsn_ti												Wikipedia:Segmentation_(biology)		biological_process											owl:Class	
GO:0090647	biolink:NamedThing	modulation of age-related behavioral decline	Any process that modulates the processes that arise as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory.	got7fsn_ti							tb	2015-06-15T12:45:44Z						biological_process											owl:Class	
GO:0002170	biolink:NamedThing	high-affinity IgA receptor activity	Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	high affinity IgA receptor activity						hjd	2010-05-06T05:00:11Z						molecular_function											owl:Class	
GO:0019766	biolink:NamedThing	IgA receptor activity	Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0048040	biolink:NamedThing	UDP-glucuronate decarboxylase activity	Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose.	got7fsn_ti	UDPglucuronate decarboxylase activity|UDP-glucuronic acid decarboxylase activity|uridine-diphosphoglucuronate decarboxylase activity|UDP-D-glucuronate carboxy-lyase activity|UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)											KEGG_REACTION:R01384|MetaCyc:UDP-GLUCURONATE-DECARBOXYLASE-RXN|RHEA:23916|EC:4.1.1.35		molecular_function											owl:Class	
GO:0101030	biolink:NamedThing	tRNA-guanine transglycosylation	The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine.	got7fsn_ti														biological_process											owl:Class	
GO:0018631	biolink:NamedThing	phenylacetate hydroxylase activity	Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate.	got7fsn_ti												UM-BBD_reactionID:r0036|EC:1.14.13.-		molecular_function											owl:Class	
GO:0031269	biolink:NamedThing	pseudopodium assembly	The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane.	got7fsn_ti	pseudopodium formation|pseudopodium extension													biological_process											owl:Class	
GO:0031268	biolink:NamedThing	pseudopodium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.	got7fsn_ti	pseudopodium organisation|pseudopodium organization and biogenesis													biological_process											owl:Class	
GO:0038033	biolink:NamedThing	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.	got7fsn_ti	VEGF-mediated chemotactic endothelial cell migration|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signalling pathway|positive regulation of endothelial cell chemotaxis by VEGF/VEGFR signaling pathway|VEGF-VEGFR-induced endothelial cell chemotaxis|vascular endothelial growth factor receptor signaling pathway involved in endothelial cell chemotaxis						bf	2011-09-19T02:36:37Z						biological_process											owl:Class	
GO:0048010	biolink:NamedThing	vascular endothelial growth factor receptor signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	VEGF receptor signaling pathway|VEGFR signaling pathway|VEGF receptor signalling pathway				In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. In contrast, the VEGFR refers to PR:000001971. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0048010 is for annotation of any pathway in which a ligand (VEGF or an alternative growth factor) binds and activates a VEGFR (PR:000001971). For annotation of signaling pathways where a VEGF binds to a cell surface receptor (VEGFR, PDGFR etc.), consider 'vascular endothelial growth factor signaling pathway ; GO:0038084'.									biological_process											owl:Class	
GO:0140405	biolink:NamedThing	spindle pole body-led chromosome movement during mitotic interphase	A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18373|https://github.com/geneontology/go-ontology/issues/19149					pg	2019-12-10T09:13:47Z						biological_process											owl:Class	
GO:0051303	biolink:NamedThing	establishment of chromosome localization	The directed movement of a chromosome to a specific location.	got7fsn_ti	chromosome positioning|establishment of chromosome localisation													biological_process											owl:Class	
GO:0102408	biolink:NamedThing	sn-2-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate <=> coenzyme A + sn-2-C16:0-DCA-LPA.	got7fsn_ti												MetaCyc:RXN-13735		molecular_function											owl:Class	
GO:0018838	biolink:NamedThing	mandelate racemase activity	Catalysis of the reaction: (S)-mandelate = (R)-mandelate.	got7fsn_ti												RHEA:13945|EC:5.1.2.2|MetaCyc:MANDELATE-RACEMASE-RXN|UM-BBD_reactionID:r0091		molecular_function											owl:Class	
GO:0016856	biolink:NamedThing	racemase and epimerase activity, acting on hydroxy acids and derivatives	Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule.	got7fsn_ti												EC:5.1.2.-		molecular_function											owl:Class	
GO:0018159	biolink:NamedThing	peptidyl-methionine oxidation	The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone.	got7fsn_ti												RESID:AA0251		biological_process											owl:Class	
GO:0018206	biolink:NamedThing	peptidyl-methionine modification	The modification of peptidyl-methionine.	got7fsn_ti														biological_process											owl:Class	
GO:0007287	biolink:NamedThing	Nebenkern assembly	Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern.	got7fsn_ti	Nebenkern formation|Nebenkern assembly				See also the cellular component term 'Nebenkern ; GO:0016006', and the fly_anatomy.ontology term 'Nebenkern ; FBbt:00004943'.									biological_process											owl:Class	
GO:0003006	biolink:NamedThing	developmental process involved in reproduction	A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.	got7fsn_ti	puberty|reproductive developmental process													biological_process											owl:Class	
GO:0034533	biolink:NamedThing	1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate.	got7fsn_ti												UM-BBD_reactionID:r0764		molecular_function											owl:Class	
GO:0016701	biolink:NamedThing	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.	got7fsn_ti	oxygenase|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous											EC:1.13.-.-		molecular_function											owl:Class	
GO:0031173	biolink:NamedThing	otolith mineralization completed early in development	The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear.	got7fsn_ti	otoconia mineralization|otoconium mineralization													biological_process											owl:Class	
GO:0045299	biolink:NamedThing	otolith mineralization	The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.	got7fsn_ti														biological_process											owl:Class	
GO:0061362	biolink:NamedThing	negative regulation of maintenance of bipolar cell polarity regulating cell shape	Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.	got7fsn_ti							dph	2010-10-13T09:03:42Z						biological_process											owl:Class	
GO:2000115	biolink:NamedThing	regulation of maintenance of bipolar cell polarity regulating cell shape	Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.	got7fsn_ti							dph	2010-09-21T06:33:26Z						biological_process											owl:Class	
GO:0052891	biolink:NamedThing	aliphatic (S)-hydroxynitrile lyase activity	Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide.	got7fsn_ti	oxynitrilase activity|(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity|(S)-hydroxynitrile lyase activity|(S)-cyanohydrin producing hydroxynitrile lyase activity|(S)-oxynitrilase activity|(S)-selective hydroxynitrile lyase activity|hydroxynitrile lyase activity											EC:4.1.2.47|MetaCyc:RXN-11731		molecular_function											owl:Class	
GO:0032919	biolink:NamedThing	spermine acetylation	The modification of spermine by addition of acetyl groups.	got7fsn_ti														biological_process											owl:Class	
GO:0032917	biolink:NamedThing	polyamine acetylation	The modification of polyamines by addition of acetyl groups.	got7fsn_ti														biological_process											owl:Class	
GO:0070227	biolink:NamedThing	lymphocyte apoptotic process	Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.	got7fsn_ti	lymphocyte apoptosis				Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).									biological_process											owl:Class	
GO:0071887	biolink:NamedThing	leukocyte apoptotic process	Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.	got7fsn_ti	leukocyte apoptosis				Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).		mah	2010-09-14T12:44:09Z						biological_process											owl:Class	
GO:0033455	biolink:NamedThing	GCA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GCA codon.	got7fsn_ti	alanine tRNA				Note that in the standard genetic code, GCA codes for alanine.									molecular_function											owl:Class	
GO:0030533	biolink:NamedThing	triplet codon-amino acid adaptor activity	The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.	got7fsn_ti	tRNA|transfer RNA				Note that this term can be used in place of the obsolete term 'transfer RNA ; GO:0005563'.									molecular_function											owl:Class	
GO:0050954	biolink:NamedThing	sensory perception of mechanical stimulus	The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti	mechanosensory perception|perception of mechanical stimulus|chemi-mechanical coupling													biological_process											owl:Class	
GO:0007600	biolink:NamedThing	sensory perception	The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti												Wikipedia:Perception		biological_process											owl:Class	
GO:0001892	biolink:NamedThing	embryonic placenta development	The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	got7fsn_ti	fetal placenta development													biological_process											owl:Class	
GO:0048568	biolink:NamedThing	embryonic organ development	Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti	embryonic organogenesis													biological_process											owl:Class	
GO:0009639	biolink:NamedThing	response to red or far red light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti														biological_process											owl:Class	
GO:0009416	biolink:NamedThing	response to light stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.	got7fsn_ti														biological_process											owl:Class	
GO:0018573	biolink:NamedThing	2-aminophenol 1,6-dioxygenase activity	Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0305		molecular_function											owl:Class	
GO:0018596	biolink:NamedThing	dimethylsilanediol hydroxylase activity	Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol.	got7fsn_ti	DMSD hydroxylase activity											UM-BBD_reactionID:r0637		molecular_function											owl:Class	
GO:0070467	biolink:NamedThing	RC-1 DNA recombination complex	A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA.	got7fsn_ti	RC-1 complex (recombination complex 1)|DNA recombination complex RC-1													cellular_component											owl:Class	
GO:0048071	biolink:NamedThing	sex-specific pigmentation	Establishment of a pattern of pigment in one sex that is not observed in the other sex.	got7fsn_ti														biological_process											owl:Class	
GO:0018477	biolink:NamedThing	benzaldehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.	got7fsn_ti	benzaldehyde:NADP+ oxidoreductase|NADP-linked benzaldehyde dehydrogenase											UM-BBD_enzymeID:e0079|MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NADP+-RXN|EC:1.2.1.7|RHEA:21660		molecular_function											owl:Class	
GO:0033721	biolink:NamedThing	aldehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.	got7fsn_ti	aldehyde:NADP+ oxidoreductase activity|NADP-acetaldehyde dehydrogenase activity|NADP-dependent aldehyde dehydrogenase activity											RHEA:11888|EC:1.2.1.4|MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN		molecular_function											owl:Class	
GO:0008481	biolink:NamedThing	sphinganine kinase activity	Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate.	got7fsn_ti	sphingosine kinase (phosphorylating)|sphingosine kinase activity|ATP:sphinganine 1-phosphotransferase activity|dihydrosphingosine kinase activity|dihydrosphingosine kinase (phosphorylating)										GO:0001728	MetaCyc:SPHINGANINE-KINASE-RXN|RHEA:15465|Reactome:R-HSA-428214|EC:2.7.1.91		molecular_function											owl:Class	
GO:0001727	biolink:NamedThing	lipid kinase activity	Catalysis of the phosphorylation of a simple or complex lipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0019253	biolink:NamedThing	reductive pentose-phosphate cycle	The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate.	got7fsn_ti	Calvin cycle|C3 photosynthesis				See also the molecular function term 'ribulose-bisphosphate carboxylase activity ; GO:0016984'.							MetaCyc:CALVIN-PWY		biological_process											owl:Class	
GO:0019685	biolink:NamedThing	photosynthesis, dark reaction	A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.	got7fsn_ti														biological_process											owl:Class	
GO:0031603	biolink:NamedThing	cytosolic proteasome core complex	The core complex of a proteasome located in the cytosol of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0005839	biolink:NamedThing	proteasome core complex	A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.	got7fsn_ti	20S proteasome|20S core complex|macropain|PA28gamma-20S proteasome										GO:0000503			cellular_component											owl:Class	
GO:0052344	biolink:NamedThing	positive regulation by symbiont of host phytoalexin production	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of phytoalexin production in other organism involved in symbiotic interaction|stimulation by symbiont of host phytoalexin production|upregulation by symbiont of host phytoalexin production|up-regulation by symbiont of host phytoalexin production|activation by symbiont of host phytoalexin production|up regulation by symbiont of host phytoalexin production										GO:0052329			biological_process											owl:Class	
GO:0052559	biolink:NamedThing	induction by symbiont of host immune response	Any process in which a symbiont activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by symbiont of host immune response|upregulation by symbiont of host immune response|positive regulation by symbiont of host immune response|up-regulation by symbiont of host immune response|positive regulation by organism of immune response of other organism involved in symbiotic interaction|induction by organism of immune response of other organism involved in symbiotic interaction|up regulation by symbiont of host immune response|stimulation by symbiont of host immune response										GO:0052556|GO:0052558|GO:0052555			biological_process											owl:Class	
GO:0043870	biolink:NamedThing	N-acetyl-gamma-aminoadipyl-phosphate reductase activity	Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH.	got7fsn_ti	AGPR|ArgC|NAGSA dehydrogenase activity|LysY|N-acetyl-aminoadipate semialdehyde dehydrogenase activity|N-acetyl-alpha-glutamyl-phosphate reductase activity				This function is part of the prokaryotic alpha-aminoadipate lysine biosynthesis pathway.							RHEA:41948|MetaCyc:RXN-5183		molecular_function											owl:Class	
GO:0021832	biolink:NamedThing	cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions	The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.	got7fsn_ti														biological_process											owl:Class	
GO:0098742	biolink:NamedThing	cell-cell adhesion via plasma-membrane adhesion molecules	The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0036312	biolink:NamedThing	phosphatidylinositol 3-kinase regulatory subunit binding	Binding to a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location.	got7fsn_ti	PI3K regulatory subunit binding|p85 binding						bf	2012-08-16T10:58:45Z						molecular_function											owl:Class	
GO:0043548	biolink:NamedThing	phosphatidylinositol 3-kinase binding	Binding to a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.	got7fsn_ti	PI3K binding|phosphoinositide 3-kinase binding													molecular_function											owl:Class	
GO:0060085	biolink:NamedThing	smooth muscle relaxation of the bladder outlet	A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body.	got7fsn_ti	synaptic transmission involved in urination													biological_process											owl:Class	
GO:0061206	biolink:NamedThing	mesonephros morphogenesis	The process in which the anatomical structures of the mesonephros are generated and organized.	got7fsn_ti	Wolffian body morphogenesis						dph	2010-08-17T03:11:10Z						biological_process											owl:Class	
GO:0060993	biolink:NamedThing	kidney morphogenesis	Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti							dph	2010-01-19T08:16:55Z						biological_process											owl:Class	
GO:0030186	biolink:NamedThing	melatonin metabolic process	The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine).	got7fsn_ti	melatonin metabolism													biological_process											owl:Class	
GO:0042430	biolink:NamedThing	indole-containing compound metabolic process	The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.	got7fsn_ti	indole derivative metabolic process|indole derivative metabolism|indole and derivative metabolism|ketole metabolism|indole-containing compound metabolism|ketole metabolic process|indole and derivative metabolic process										GO:0042434			biological_process											owl:Class	
GO:0033428	biolink:NamedThing	CAG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CAG codon.	got7fsn_ti	glutamine tRNA				Note that in the standard genetic code, CAG codes for glutamine.									molecular_function											owl:Class	
GO:0044593	biolink:NamedThing	iron-sulfur-molybdenum cofactor assembly	The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.	got7fsn_ti	iron molybdenum cofactor assembly|iron molybdenum cofactor biosynthesis|FeMoco biosynthetic process|iron molybdenum cofactor biosynthetic process|FeMoco assembly						jl	2012-04-26T04:01:53Z						biological_process											owl:Class	
GO:0016226	biolink:NamedThing	iron-sulfur cluster assembly	The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.	got7fsn_ti	iron-sulphur cluster assembly|iron-sulfur cluster biosynthesis													biological_process											owl:Class	
GO:0070254	biolink:NamedThing	mucus secretion	The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function.	got7fsn_ti	mucus production													biological_process											owl:Class	
GO:0032941	biolink:NamedThing	secretion by tissue	The controlled release of a substance by a tissue.	got7fsn_ti	tissue secretion|expulsion of gland contents													biological_process											owl:Class	
GO:0098966	biolink:NamedThing	perisynaptic extracellular matrix	The portion of the extracellular matrix that lies within the perisynaptic space.	got7fsn_ti	extrasynaptic extracellular matrix|perisynaptic ECM													cellular_component											owl:Class	
GO:0062023	biolink:NamedThing	collagen-containing extracellular matrix	An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.	got7fsn_ti							dph	2018-04-13T12:47:21Z						cellular_component											owl:Class	
GO:0016746	biolink:NamedThing	acyltransferase activity	Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring acyl groups|acyltransferase activity	https://github.com/geneontology/go-ontology/issues/20486									GO:0008415	Reactome:R-HSA-193491|EC:2.3.-.-|Reactome:R-HSA-159431|Reactome:R-HSA-192312|Reactome:R-HSA-8858298|Reactome:R-HSA-6792572		molecular_function											owl:Class	
GO:0018278	biolink:NamedThing	N-terminal peptidyl-threonine deamination	The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid.	got7fsn_ti												RESID:AA0129		biological_process											owl:Class	
GO:0018058	biolink:NamedThing	N-terminal protein amino acid deamination, from amino carbon	The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol.	got7fsn_ti												RESID:AA0127|RESID:AA0129|RESID:AA0128		biological_process											owl:Class	
GO:0099137	biolink:NamedThing	altruistic, chimeric, non-reproductive fruiting body development	Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell.	got7fsn_ti	fully co-operative, chimeric, non-reproductive fruiting body development													biological_process											owl:Class	
GO:0099136	biolink:NamedThing	chimeric non-reproductive fruiting body development	Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes.	got7fsn_ti														biological_process											owl:Class	
GO:0071720	biolink:NamedThing	sodium-independent prostaglandin transport	The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							mah	2010-03-10T03:09:10Z						biological_process											owl:Class	
GO:0071718	biolink:NamedThing	sodium-independent icosanoid transport	The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.	got7fsn_ti	sodium-independent eicosanoid transport						mah	2010-03-10T03:05:13Z						biological_process											owl:Class	
GO:0071743	biolink:NamedThing	IgE immunoglobulin complex, circulating	A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	IgE antibody				Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0042571	biolink:NamedThing	immunoglobulin complex, circulating	An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.	got7fsn_ti	antibody				Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.							Wikipedia:Antibody		cellular_component											owl:Class	
GO:0052922	biolink:NamedThing	hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity	Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate.	got7fsn_ti	hexaprenyl pyrophosphate synthetase activity|hexaprenyl diphosphate synthase activity|(all-trans)-hexaprenyl-diphosphate synthase activity|(all-E) hexaprenyl diphosphate synthase activity											KEGG_REACTION:R09246|MetaCyc:RXN-11485|RHEA:27555|EC:2.5.1.82		molecular_function											owl:Class	
GO:0004659	biolink:NamedThing	prenyltransferase activity	Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).	got7fsn_ti												MetaCyc:GPPSYN-RXN|Reactome:R-HSA-6806674		molecular_function											owl:Class	
GO:1902549	biolink:NamedThing	protein localization to Mei2 nuclear dot	A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot.	got7fsn_ti	protein localisation to Mei2 nuclear dot|protein localization in Mei2 nuclear dot|protein localization to Mei2 dot|protein localisation in Mei2 nuclear dot						mah	2013-12-04T16:17:06Z						biological_process											owl:Class	
GO:0034613	biolink:NamedThing	cellular protein localization	Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.	got7fsn_ti	cellular protein localisation|channel localizer activity										GO:0016249			biological_process											owl:Class	
GO:0008406	biolink:NamedThing	gonad development	The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.	got7fsn_ti	gonadogenesis													biological_process											owl:Class	
GO:0048608	biolink:NamedThing	reproductive structure development	The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.	got7fsn_ti														biological_process											owl:Class	
GO:0004129	biolink:NamedThing	cytochrome-c oxidase activity	Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.	got7fsn_ti	ba3-type cytochrome c oxidase|cbb3-type cytochrome c oxidase|cytochrome aa3 activity|cytochrome c oxidase activity|Warburg's respiratory enzyme activity|complex IV (mitochondrial electron transport) activity|caa3-type cytochrome c oxidase|cytochrome oxidase activity|aa3-type cytochrome c oxidase|indophenolase|indophenol oxidase|cytochrome a3 activity	https://github.com/geneontology/go-ontology/issues/21275|https://github.com/geneontology/go-ontology/issues/20924			The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.							RHEA:11436|MetaCyc:CYTOCHROME-C-OXIDASE-RXN|Reactome:R-HSA-163214|EC:7.1.1.9		molecular_function											owl:Class	
GO:0015453	biolink:NamedThing	oxidoreduction-driven active transmembrane transporter activity	Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.	got7fsn_ti	oxidoreduction-driven transporter											TC:3.D		molecular_function											owl:Class	
GO:0017178	biolink:NamedThing	diphthine-ammonia ligase activity	Catalysis of the reaction: ATP + diphthine + NH(4)(+) = ADP + diphthamide + H(+) + phosphate.	got7fsn_ti	diphthamide synthetase activity|diphthine:ammonia ligase (ADP-forming)|diphthamide synthase activity											RHEA:19753|KEGG_REACTION:R03613|Reactome:R-HSA-5358475|EC:6.3.1.14|MetaCyc:DIPHTINE--AMMONIA-LIGASE-RXN		molecular_function											owl:Class	
GO:0016880	biolink:NamedThing	acid-ammonia (or amide) ligase activity	Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti	amide synthase activity											EC:6.3.1.-		molecular_function											owl:Class	
GO:1901362	biolink:NamedThing	organic cyclic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organic cyclic compound.	got7fsn_ti	organic cyclic compound anabolism|organic cyclic compound biosynthesis|organic cyclic compound formation|organic cyclic compound synthesis						bf	2012-09-14T09:05:22Z						biological_process											owl:Class	
GO:1901576	biolink:NamedThing	organic substance biosynthetic process	The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.	got7fsn_ti	organic molecular entity biosynthetic process|organic substance synthesis|organic substance biosynthesis|organic molecular entity biosynthesis|organic substance formation|organic molecular entity anabolism|organic molecular entity formation|organic molecular entity synthesis|organic substance anabolism						pr	2012-11-05T11:04:40Z						biological_process											owl:Class	
GO:0090693	biolink:NamedThing	plant organ senescence	The process that occurs in a plant organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism.	got7fsn_ti							tb	2016-08-24T10:50:29Z						biological_process											owl:Class	
GO:0007568	biolink:NamedThing	aging	A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).	got7fsn_ti	ageing										GO:0016280	Wikipedia:Aging		biological_process											owl:Class	
GO:0061634	biolink:NamedThing	alpha-D-xyloside xylohydrolase	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.	got7fsn_ti	alpha-xylosidase						dph	2014-07-28T08:12:39Z				EC:3.2.1.177		molecular_function											owl:Class	
GO:0003403	biolink:NamedThing	optic vesicle formation	The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.	got7fsn_ti							dph	2009-12-21T01:42:37Z						biological_process											owl:Class	
GO:0021508	biolink:NamedThing	floor plate formation	The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.	got7fsn_ti														biological_process											owl:Class	
GO:0033806	biolink:NamedThing	fluorothreonine transaldolase activity	Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine.	got7fsn_ti	fluoroacetaldehyde:L-threonine aldehydetransferase activity											RHEA:11748|EC:2.2.1.8		molecular_function											owl:Class	
GO:0051139	biolink:NamedThing	metal ion:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).	got7fsn_ti	metal ion:hydrogen antiporter activity											Reactome:R-HSA-435171		molecular_function											owl:Class	
GO:0015299	biolink:NamedThing	solute:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).	got7fsn_ti	solute:hydrogen antiporter activity|L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity											Reactome:R-HSA-5625574|Reactome:R-HSA-434650|Reactome:R-HSA-597628		molecular_function											owl:Class	
GO:0071907	biolink:NamedThing	determination of digestive tract left/right asymmetry	Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.	got7fsn_ti	determination of gut left/right asymmetry|determination of left/right asymmetry of the digestive tract						mah	2010-09-22T10:14:29Z						biological_process											owl:Class	
GO:0007368	biolink:NamedThing	determination of left/right symmetry	The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.	got7fsn_ti	determination of left/right asymmetry													biological_process											owl:Class	
GO:0072537	biolink:NamedThing	fibroblast activation	A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.	got7fsn_ti							mah	2011-01-14T04:35:08Z						biological_process											owl:Class	
GO:0001775	biolink:NamedThing	cell activation	A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	got7fsn_ti														biological_process											owl:Class	
GO:0061346	biolink:NamedThing	planar cell polarity pathway involved in heart morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.	got7fsn_ti							dph	2010-09-30T12:47:24Z						biological_process											owl:Class	
GO:0061341	biolink:NamedThing	non-canonical Wnt signaling pathway involved in heart development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time.	got7fsn_ti	non-canonical Wnt receptor signaling pathway involved in heart development|non-canonical Wnt receptor signalling pathway involved in heart development|non-canonical Wnt-activated signaling pathway involved in heart development						dph	2010-09-29T11:27:34Z						biological_process											owl:Class	
GO:0005170	biolink:NamedThing	neurotrophin TRKC receptor binding	Binding to a neurotrophin TRKC receptor.	got7fsn_ti	neurotrophin TRKC receptor ligand													molecular_function											owl:Class	
GO:0005167	biolink:NamedThing	neurotrophin TRK receptor binding	Binding to a neurotrophin TRK receptor.	got7fsn_ti	neurotrophin TRK receptor ligand													molecular_function											owl:Class	
GO:0102790	biolink:NamedThing	cyanidin 5,3-O-glycosyltransferase activity	Catalysis of the reaction: cyanidin 5-O-beta-D-glucoside + UDP-alpha-D-glucose = cyanin betaine + UDP.	got7fsn_ti												MetaCyc:RXN-8006		molecular_function											owl:Class	
GO:1903513	biolink:NamedThing	endoplasmic reticulum to cytosol transport	The directed movement of substances from endoplasmic reticulum to cytosol.	got7fsn_ti	ER to cytosol transport						rl	2014-10-02T11:24:34Z						biological_process											owl:Class	
GO:0046907	biolink:NamedThing	intracellular transport	The directed movement of substances within a cell.	got7fsn_ti	single-organism intracellular transport|single organism intracellular transport						jl	2013-12-18T14:04:50Z			GO:1902582			biological_process											owl:Class	
GO:0102990	biolink:NamedThing	5-n-alk(en)ylresorcinol O-methyltransferase activity	Catalysis of the reaction: 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine  <=> H+ + 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:26325|MetaCyc:RXN-9619		molecular_function											owl:Class	
GO:0035755	biolink:NamedThing	cardiolipin hydrolase activity	Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/8492|https://github.com/geneontology/go-ontology/issues/21230					bf	2011-03-24T10:14:05Z				Reactome:R-HSA-8954398		molecular_function											owl:Class	
GO:0004620	biolink:NamedThing	phospholipase activity	Catalysis of the hydrolysis of a glycerophospholipid.	got7fsn_ti												Reactome:R-HSA-6792445|EC:3.1.1.-|Reactome:R-HSA-6786650		molecular_function											owl:Class	
GO:0036017	biolink:NamedThing	response to erythropoietin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis.	got7fsn_ti							bf	2011-10-12T10:11:04Z						biological_process											owl:Class	
GO:0006620	biolink:NamedThing	posttranslational protein targeting to endoplasmic reticulum membrane	The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.	got7fsn_ti	posttranslational protein targeting to ER membrane|posttranslational endoplasmic reticulum membrane targeting|posttranslational endoplasmic reticulum protein-membrane targeting|SRP-independent endoplasmic reticulum protein-membrane targeting|posttranslational protein endoplasmic reticulum membrane targeting													biological_process											owl:Class	
GO:0045047	biolink:NamedThing	protein targeting to ER	The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.	got7fsn_ti	protein-endoplasmic reticulum targeting|protein-ER targeting|protein targeting to endoplasmic reticulum													biological_process											owl:Class	
GO:0035577	biolink:NamedThing	azurophil granule membrane	The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.	got7fsn_ti	primary granule membrane						bf	2010-10-05T01:29:10Z						cellular_component											owl:Class	
GO:0030667	biolink:NamedThing	secretory granule membrane	The lipid bilayer surrounding a secretory granule.	got7fsn_ti	secretory vesicle membrane													cellular_component											owl:Class	
GO:0030956	biolink:NamedThing	glutamyl-tRNA(Gln) amidotransferase complex	A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms.	got7fsn_ti	AdT|GatFAB|GatCAB				Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity ; GO:0050567'.									cellular_component											owl:Class	
GO:0140535	biolink:NamedThing	intracellular protein-containing complex	A protein-containing complex located intracellularly.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19952					pg	2020-10-28T14:40:16Z						cellular_component											owl:Class	
GO:0030896	biolink:NamedThing	checkpoint clamp complex	Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage.	got7fsn_ti	Rad9-Hus1-Rad1 (9-1-1) clamp complex|CCC				Note that the following subunit names have been used: human RAD9/RAD1/HUS1; S. pombe Rad9/Rad1/Hus1; S. cerevisiae Ddc1p/Rad17p/Mec3p.									cellular_component											owl:Class	
GO:0046888	biolink:NamedThing	negative regulation of hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.	got7fsn_ti	inhibition of hormone secretion|down-regulation of hormone secretion|downregulation of hormone secretion|down regulation of hormone secretion													biological_process											owl:Class	
GO:0023057	biolink:NamedThing	negative regulation of signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.	got7fsn_ti	negative regulation of signaling process|negative regulation of signalling process							2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0075289	biolink:NamedThing	aplanospore formation	The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.	got7fsn_ti														biological_process											owl:Class	
GO:0034300	biolink:NamedThing	sporangiospore formation	The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.	got7fsn_ti														biological_process											owl:Class	
GO:0035545	biolink:NamedThing	determination of left/right asymmetry in nervous system	The establishment of the nervous system with respect to the left and right halves.	got7fsn_ti							bf	2010-05-11T01:53:33Z						biological_process											owl:Class	
GO:0070854	biolink:NamedThing	myosin VI heavy chain binding	Binding to a heavy chain of a myosin VI complex.	got7fsn_ti							mah	2009-08-13T01:44:05Z						molecular_function											owl:Class	
GO:0070853	biolink:NamedThing	myosin VI binding	Binding to a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.	got7fsn_ti							mah	2009-08-13T01:28:36Z						molecular_function											owl:Class	
GO:0016560	biolink:NamedThing	protein import into peroxisome matrix, docking	The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane.	got7fsn_ti	protein docking during protein import into peroxisome matrix|protein transport into peroxisome matrix, docking|protein docking during protein transport into peroxisome matrix|peroxisome matrix protein import, docking|peroxisome receptor docking|protein docking during peroxisome matrix protein import													biological_process											owl:Class	
GO:0008104	biolink:NamedThing	protein localization	Any process in which a protein is transported to, or maintained in, a specific location.	got7fsn_ti	asymmetric protein localisation|establishment and maintenance of asymmetric protein localization|protein localisation|asymmetric protein localization|establishment and maintenance of protein localization										GO:0008105			biological_process											owl:Class	
GO:0030125	biolink:NamedThing	clathrin vesicle coat	A clathrin coat found on a vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0030118	biolink:NamedThing	clathrin coat	A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes.	got7fsn_ti	clathrin cage										GO:0016190	Wikipedia:Clathrin|NIF_Subcellular:sao879919129		cellular_component											owl:Class	
GO:0044845	biolink:NamedThing	chain elongation of O-linked mannose residue	Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules.	got7fsn_ti					Example annotations to this term include the S. cerevisiae alpha1,2-mannosyltransferases ScKre2p, ScKtr1p and ScKtr3pof the KTR family.		jl	2014-05-08T15:56:39Z						biological_process											owl:Class	
GO:0035268	biolink:NamedThing	protein mannosylation	The addition of a mannose residue to a protein acceptor molecule.	got7fsn_ti	protein amino acid mannosylation													biological_process											owl:Class	
GO:0004632	biolink:NamedThing	phosphopantothenate--cysteine ligase activity	Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives.	got7fsn_ti	(R)-4'-phosphopantothenate:L-cysteine ligase activity|phosphopantothenate-cysteine ligase activity|phosphopantothenoylcysteine synthetase activity											Reactome:R-HSA-196753|RHEA:19397|EC:6.3.2.5|MetaCyc:P-PANTOCYSLIG-RXN		molecular_function											owl:Class	
GO:0016881	biolink:NamedThing	acid-amino acid ligase activity	Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti	peptide synthase activity											EC:6.3.2.-		molecular_function											owl:Class	
GO:0097143	biolink:NamedThing	PUMA-BCL-xl complex	A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:44:10Z						cellular_component											owl:Class	
GO:0097136	biolink:NamedThing	Bcl-2 family protein complex	A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed.	got7fsn_ti							pr	2011-08-02T01:34:19Z						cellular_component											owl:Class	
GO:0033131	biolink:NamedThing	regulation of glucokinase activity	Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.	got7fsn_ti	glucokinase regulator													biological_process											owl:Class	
GO:0010906	biolink:NamedThing	regulation of glucose metabolic process	Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.	got7fsn_ti	regulation of glucose metabolism													biological_process											owl:Class	
GO:0047435	biolink:NamedThing	5-guanidino-2-oxopentanoate decarboxylase activity	Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO(2).	got7fsn_ti	2-oxo-5-guanidinopentanoate carboxy-lyase (4-guanidinobutanal-forming)|2-oxo-5-guanidinopentanoate decarboxylase activity|alpha-ketoarginine decarboxylase activity|2-oxo-5-guanidinovalerate alpha-ketoarginine decarboxylase activity|2-oxo-5-guanidinopentanoate carboxy-lyase activity											MetaCyc:4.1.1.75-RXN|KEGG_REACTION:R03178|RHEA:11340|EC:4.1.1.75		molecular_function											owl:Class	
GO:0018519	biolink:NamedThing	cis-dihydroethylcatechol dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH.	got7fsn_ti	cis-ethylbenzene glycol dehydrogenase activity|cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase activity											MetaCyc:1.3.1.66-RXN|RHEA:18101|UM-BBD_reactionID:r0309|EC:1.3.1.66|KEGG_REACTION:R05313		molecular_function											owl:Class	
GO:0097057	biolink:NamedThing	TRAF2-GSTP1 complex	A protein complex comprising tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and glutathione S-transferase pi 1 (GSTP1). This complex is thought to disrupt the TNF signaling cascade, thus down-regulating inflammatory responses.	got7fsn_ti							pr	2011-05-26T10:35:45Z						cellular_component											owl:Class	
GO:0052905	biolink:NamedThing	tRNA (guanine(9)-N(1))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine.	got7fsn_ti	tRNA(m(1)G(9)/m(1)A(9))Mtase activity|tRNA(m(1)G(9)/m(1)A(9))-methyltransferase activity|tRNA m(1)G(9) Mtase activity|tRNA (guanine-N(1)-)-methyltransferase activity|tRNA m(1)G(9)-methyltransferase activity											EC:2.1.1.221|RHEA:43156|MetaCyc:RXN-12459		molecular_function											owl:Class	
GO:0009019	biolink:NamedThing	tRNA (guanine-N1-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.	got7fsn_ti	transfer ribonucleate guanine 1-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-N1-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-1-N-)-methyltransferase activity|tRNA guanine 1-methyltransferase activity											Reactome:R-HSA-6782859|Reactome:R-HSA-6786621|Reactome:R-HSA-6787591		molecular_function											owl:Class	
GO:0071363	biolink:NamedThing	cellular response to growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	got7fsn_ti							mah	2009-12-11T03:05:07Z						biological_process											owl:Class	
GO:0046467	biolink:NamedThing	membrane lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.	got7fsn_ti	membrane lipid synthesis|membrane lipid biosynthesis|membrane lipid anabolism|membrane lipid formation													biological_process											owl:Class	
GO:0048800	biolink:NamedThing	antennal morphogenesis	The process in which the anatomical structures of the antenna are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0001555	biolink:NamedThing	oocyte growth	The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.	got7fsn_ti														biological_process											owl:Class	
GO:0051723	biolink:NamedThing	protein methylesterase activity	Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.	got7fsn_ti	protein carboxylic ester hydrolase activity|protein methyl-esterase activity|protein carboxyl methylesterase activity|PME activity											Reactome:R-HSA-5367022		molecular_function											owl:Class	
GO:0072764	biolink:NamedThing	cellular response to reversine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.	got7fsn_ti							mah	2012-11-09T11:52:22Z						biological_process											owl:Class	
GO:0071415	biolink:NamedThing	cellular response to purine-containing compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.	got7fsn_ti	cellular response to purine						mah	2009-12-14T03:12:20Z						biological_process											owl:Class	
GO:0102510	biolink:NamedThing	pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + vanillate + H+.	got7fsn_ti												MetaCyc:RXN-14439|EC:2.4.1.299		molecular_function											owl:Class	
GO:0072756	biolink:NamedThing	cellular response to paraquat	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.	got7fsn_ti							mah	2012-11-07T12:08:59Z						biological_process											owl:Class	
GO:0071310	biolink:NamedThing	cellular response to organic substance	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.	got7fsn_ti							mah	2009-12-10T04:46:04Z						biological_process											owl:Class	
GO:0003886	biolink:NamedThing	DNA (cytosine-5-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.	got7fsn_ti	deoxyribonucleic acid (cytosine-5-)-methyltransferase activity|type II DNA methylase activity|DNA cytosine methylase activity|DNA cytosine C5 methylase activity|methylphosphotriester-DNA methyltransferase activity|cytosine DNA methylase activity|DNA-cytosine 5-methylase activity|deoxyribonucleic (cytosine-5-)-methyltransferase activity|deoxyribonucleic methylase activity|cytosine DNA methyltransferase activity|restriction-modification system activity|cytosine-specific DNA methyltransferase activity|site-specific DNA-methyltransferase (cytosine-specific) activity|modification methylase activity|DNA 5-cytosine methylase activity|DNA cytosine C(5) methylase activity|cytosine 5-methyltransferase activity|DNA-cytosine methyltransferase activity|S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity				Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37).						GO:0008326	EC:2.1.1.37|MetaCyc:2.1.1.73-RXN|RHEA:13681		molecular_function											owl:Class	
GO:0009008	biolink:NamedThing	DNA-methyltransferase activity	Catalysis of the transfer of a methyl group to a DNA molecule.	got7fsn_ti	DNA transmethylase activity|deoxyribonucleate methyltransferase activity|deoxyribonucleic acid methylase activity|DNA methylase|Type II DNA methylase|deoxyribonucleate methylase activity|deoxyribonucleic acid methyltransferase activity|deoxyribonucleic acid modification methylase activity|DNA methyltransferase activity											Reactome:R-HSA-5227490		molecular_function											owl:Class	
GO:1902441	biolink:NamedThing	protein localization to meiotic spindle pole body	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body.	got7fsn_ti	protein localisation in meiotic spindle pole body|protein localization in meiotic spindle pole body|protein localisation to meiotic spindle pole body|protein location to meiotic spindle pole body|establishment of protein localization to meiotic spindle pole body						mah	2013-10-10T14:45:04Z			GO:1990945|GO:1990954			biological_process											owl:Class	
GO:0033408	biolink:NamedThing	UCG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UCG codon.	got7fsn_ti	TCG codon-amino acid adaptor activity|serine tRNA				Note that in the standard genetic code, TCG codes for serine.									molecular_function											owl:Class	
GO:0072105	biolink:NamedThing	ureteric peristalsis	A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.	got7fsn_ti							mah	2010-02-10T03:07:54Z						biological_process											owl:Class	
GO:0030432	biolink:NamedThing	peristalsis	A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards.	got7fsn_ti												Wikipedia:Peristalsis		biological_process											owl:Class	
GO:0030686	biolink:NamedThing	90S preribosome	A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0030684	biolink:NamedThing	preribosome	Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0031726	biolink:NamedThing	CCR1 chemokine receptor binding	Binding to a CCR1 chemokine receptor.	got7fsn_ti	macrophage inflammatory protein-1 alpha receptor binding|CCR1 chemokine receptor ligand													molecular_function											owl:Class	
GO:0048020	biolink:NamedThing	CCR chemokine receptor binding	Binding to a CCR chemokine receptor.	got7fsn_ti	beta chemokine receptor ligand|CCR chemokine receptor ligand|beta chemokine receptor binding													molecular_function											owl:Class	
GO:0030870	biolink:NamedThing	Mre11 complex	Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.	got7fsn_ti	RAD50-MRE11-NBN complex|Rad50-Rad32-Nbs1 complex|MRN complex|Rad50 complex|RMX complex|MRX complex													cellular_component											owl:Class	
GO:0046957	biolink:NamedThing	negative phototaxis	The directed movement of a cell or organism away from a source of light.	got7fsn_ti	negative phototactic behavior|negative taxis in response to light|negative phototactic behaviour										GO:0046955			biological_process											owl:Class	
GO:0052129	biolink:NamedThing	negative energy taxis	The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.	got7fsn_ti														biological_process											owl:Class	
GO:0033974	biolink:NamedThing	nucleoside phosphoacylhydrolase activity	Catalysis of the hydrolysis of mixed phospho-anhydride bonds.	got7fsn_ti	nucleoside-5'-phosphoacylate acylhydrolase activity											EC:3.6.1.24|MetaCyc:3.6.1.24-RXN		molecular_function											owl:Class	
GO:0016818	biolink:NamedThing	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.	got7fsn_ti												EC:3.6.1.-		molecular_function											owl:Class	
GO:0033872	biolink:NamedThing	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.	got7fsn_ti	heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A activity|glucosaminyl 3-O-sulfotransferase 3a, 3b activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity|3-OST-3|heparin-glucosamine 3-sulfotransferase 3 activity|glucosaminyl 3-O-sulfotransferase 3 activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3 activity|isoform/isozyme 3a and 3b (3-OST-3A, 3-OST-3B, HS3ST3A, HS3ST3B)											MetaCyc:2.8.2.30-RXN|EC:2.8.2.30		molecular_function											owl:Class	
GO:0034483	biolink:NamedThing	heparan sulfate sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate.	got7fsn_ti														molecular_function											owl:Class	
GO:0035768	biolink:NamedThing	endothelial cell chemotaxis to fibroblast growth factor	The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).	got7fsn_ti							bf	2011-03-31T04:32:17Z						biological_process											owl:Class	
GO:0035767	biolink:NamedThing	endothelial cell chemotaxis	The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti							bf	2011-03-31T04:31:37Z						biological_process											owl:Class	
GO:0042037	biolink:NamedThing	peptidyl-histidine methylation, to form pros-methylhistidine	The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).	got7fsn_ti	peptidyl-histidine pros-methylation										GO:0042260	RESID:AA0073		biological_process											owl:Class	
GO:0018021	biolink:NamedThing	peptidyl-histidine methylation	The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).	got7fsn_ti												RESID:AA0073|RESID:AA0317		biological_process											owl:Class	
GO:0043098	biolink:NamedThing	purine deoxyribonucleoside salvage	Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0046123	biolink:NamedThing	purine deoxyribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	purine deoxyribonucleoside anabolism|purine deoxyribonucleoside formation|purine deoxyribonucleoside biosynthesis|purine deoxyribonucleoside synthesis													biological_process											owl:Class	
GO:0009649	biolink:NamedThing	entrainment of circadian clock	The synchronization of a circadian rhythm to environmental time cues such as light.	got7fsn_ti	regulation of circadian rhythm phase													biological_process											owl:Class	
GO:0018964	biolink:NamedThing	propylene metabolic process	The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals.	got7fsn_ti	propylene metabolism											UM-BBD_pathwayID:pro		biological_process											owl:Class	
GO:0006805	biolink:NamedThing	xenobiotic metabolic process	The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	drug metabolism|xenobiotic metabolism|drug metabolic process	https://github.com/geneontology/go-ontology/issues/19460									GO:0017144	Wikipedia:Xenobiotic_metabolism|Wikipedia:Drug_metabolism		biological_process											owl:Class	
GO:0045462	biolink:NamedThing	trichothecene 3-O-acetyltransferase activity	Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis.	got7fsn_ti														molecular_function											owl:Class	
GO:0040024	biolink:NamedThing	dauer larval development	The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.	got7fsn_ti														biological_process											owl:Class	
GO:0002119	biolink:NamedThing	nematode larval development	The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.	got7fsn_ti														biological_process											owl:Class	
GO:0008967	biolink:NamedThing	phosphoglycolate phosphatase activity	Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate.	got7fsn_ti	phosphoglycolate hydrolase activity|P-glycolate phosphatase activity|phosphoglycollate phosphatase activity|2-phosphoglycolate phosphohydrolase activity|2-phosphoglycolate phosphatase activity											RHEA:14369|EC:3.1.3.18|KEGG_REACTION:R01334|MetaCyc:GPH-RXN		molecular_function											owl:Class	
GO:0016791	biolink:NamedThing	phosphatase activity	Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	got7fsn_ti	PNPPase activity|nitrophenyl phosphatase activity|para-nitrophenyl phosphatase activity|phosphatase|p-nitrophenylphosphate phosphohydrolase activity|phosphoric monoester hydrolase activity|4-nitrophenylphosphate phosphohydrolase activity|ecto-p-nitrophenyl phosphatase activity|NPPase activity|p-nitrophenylphosphatase activity|K-pNPPase activity|4-nitrophenylphosphatase activity										GO:0003869|GO:0016302	Reactome:R-HSA-9636457|Reactome:R-HSA-4419986|MetaCyc:4-NITROPHENYLPHOSPHATASE-RXN|EC:3.1.3.-		molecular_function											owl:Class	
GO:0031837	biolink:NamedThing	substance K receptor binding	Binding to a substance K receptor.	got7fsn_ti	substance K receptor ligand|neurokinin-A receptor binding													molecular_function											owl:Class	
GO:0031834	biolink:NamedThing	neurokinin receptor binding	Binding to a neurokinin receptor.	got7fsn_ti	neurokinin receptor ligand													molecular_function											owl:Class	
GO:0071047	biolink:NamedThing	polyadenylation-dependent mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.	got7fsn_ti	poly(A)-dependent mRNA catabolic process	https://github.com/geneontology/go-ontology/issues/20568					krc	2009-08-07T09:57:56Z						biological_process											owl:Class	
GO:0043633	biolink:NamedThing	polyadenylation-dependent RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA.	got7fsn_ti	polyadenylation-dependent RNA catabolic process													biological_process											owl:Class	
GO:0009535	biolink:NamedThing	chloroplast thylakoid membrane	The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.	got7fsn_ti														cellular_component											owl:Class	
GO:0055035	biolink:NamedThing	plastid thylakoid membrane	The lipid bilayer membrane of any thylakoid within a plastid.	got7fsn_ti														cellular_component											owl:Class	
GO:0008707	biolink:NamedThing	4-phytase activity	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate.	got7fsn_ti	phytate 6-phosphatase activity|6-phytase activity|6-phytase (name based on 1L-numbering system and not 1D-numbering)|myo-inositol-hexakisphosphate 6-phosphohydrolase activity|phytase activity											MetaCyc:6-PHYT-RXN|EC:3.1.3.26|RHEA:20960		molecular_function											owl:Class	
GO:0004447	biolink:NamedThing	iodide peroxidase activity	Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O.	got7fsn_ti	thyroperoxidase activity|iodinase activity|TPO activity|thyroid peroxidase activity	https://github.com/geneontology/go-ontology/issues/21027										MetaCyc:IODIDE-PEROXIDASE-RXN|EC:1.11.1.8		molecular_function											owl:Class	
GO:0004601	biolink:NamedThing	peroxidase activity	Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.	got7fsn_ti	horseradish peroxidase (HRP)|peroxidase reaction|verdoperoxidase|protoheme peroxidase|MPO|secretory plant peroxidase activity|oxyperoxidase activity|heme peroxidase|guaiacol peroxidase|thiocyanate peroxidase|myeloperoxidase activity|lactoperoxidase activity|donor:hydrogen-peroxide oxidoreductase activity|pyrocatechol peroxidase|japanese radish peroxidase|scopoletin peroxidase|bacterial catalase-peroxidase activity|extensin peroxidase|eosinophil peroxidase activity										GO:0016685|GO:0016686|GO:0016687|GO:0016693	Reactome:R-HSA-6789126|Reactome:R-HSA-209840|EC:1.11.1.-|Reactome:R-HSA-140359|Reactome:R-HSA-350901|Reactome:R-HSA-5631885|Reactome:R-HSA-2559639|Reactome:R-HSA-209925|KEGG_REACTION:R03532|Reactome:R-HSA-209973|Reactome:R-HSA-209815|Reactome:R-HSA-1222346|Reactome:R-HSA-3341296|Reactome:R-HSA-8933635|Reactome:R-HSA-6789031|MetaCyc:PEROXID-RXN|Reactome:R-HSA-8855490|Reactome:R-HSA-2309773		molecular_function											owl:Class	
GO:0071464	biolink:NamedThing	cellular response to hydrostatic pressure	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.	got7fsn_ti	cellular response to biomechanical stress|cellular response to static fluid pressure						mah	2009-12-18T11:34:07Z						biological_process											owl:Class	
GO:0051599	biolink:NamedThing	response to hydrostatic pressure	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.	got7fsn_ti	response to biomechanical stress|response to static fluid pressure													biological_process											owl:Class	
GO:0009036	biolink:NamedThing	type II site-specific deoxyribonuclease activity	Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.	got7fsn_ti	type II restriction enzyme activity											EC:3.1.21.4|MetaCyc:3.1.21.4-RXN		molecular_function											owl:Class	
GO:0015666	biolink:NamedThing	restriction endodeoxyribonuclease activity	Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.	got7fsn_ti	restriction enzyme activity|restriction endonuclease activity													molecular_function											owl:Class	
GO:0097191	biolink:NamedThing	extrinsic apoptotic signaling pathway	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	extrinsic apoptosis|extrinsic apoptotic pathway|extrinsic apoptotic signalling pathway|extrinsic apoptotic signaling pathway in presence of ligand|death receptor-mediated apoptosis				Fas acts as a death receptor with a role in apoptosis, but can also act as a non-apoptotic signal transducer.		pr	2011-11-23T09:34:28Z						biological_process											owl:Class	
GO:0007166	biolink:NamedThing	cell surface receptor signaling pathway	A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	cell surface receptor linked signaling pathway|cell surface receptor linked signalling pathway|cell surface receptor linked signal transduction													biological_process											owl:Class	
GO:0046619	biolink:NamedThing	lens placode formation involved in camera-type eye formation	Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles.	got7fsn_ti	optic placode formation involved in camera-style eye|optic placode formation in camera-type eye|optic placode formation involved in camera-type eye formation													biological_process											owl:Class	
GO:0001743	biolink:NamedThing	lens placode formation	The initial developmental process that will lead to the formation of an eye.	got7fsn_ti	optic placode formation													biological_process											owl:Class	
GO:0030520	biolink:NamedThing	intracellular estrogen receptor signaling pathway	Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).	got7fsn_ti	estrogen receptor signaling pathway|estrogen receptor signalling pathway													biological_process											owl:Class	
GO:0030518	biolink:NamedThing	intracellular steroid hormone receptor signaling pathway	A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands.	got7fsn_ti	steroid hormone receptor signalling pathway|steroid hormone receptor signaling pathway													biological_process											owl:Class	
GO:0031635	biolink:NamedThing	adenylate cyclase-inhibiting opioid receptor signaling pathway	The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	got7fsn_ti	inhibition of adenylate cyclase activity by opioid receptor signalling pathway|opioid receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by opioid receptor signaling pathway													biological_process											owl:Class	
GO:0007193	biolink:NamedThing	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).	got7fsn_ti	G protein signaling, adenylyl cyclase inhibiting pathway|GPCR signaling pathway via inhibition of adenylate cyclase activity|G-protein signaling, adenylyl cyclase inhibiting pathway|G protein signalling, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by G-protein signaling pathway|G-protein signalling, adenylate cyclase inhibiting pathway|G-protein signalling, adenylyl cyclase inhibiting pathway|G protein signaling, adenylate cyclase inhibiting pathway|adenylate cyclase-inhibiting GPCR signaling pathway|G-protein signaling, adenylate cyclase inhibiting pathway|G protein signalling, adenylyl cyclase inhibiting pathway				This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase inhibition.									biological_process											owl:Class	
GO:0045476	biolink:NamedThing	nurse cell apoptotic process	Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.	got7fsn_ti	apoptosis of nurse cells|nurse cell apoptosis|programmed cell death of nurse cells by apoptosis|invertebrate nurse cell apoptosis|nurse cell programmed cell death by apoptosis													biological_process											owl:Class	
GO:0006915	biolink:NamedThing	apoptotic process	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.	got7fsn_ti	apoptosis activator activity|commitment to apoptosis|apoptotic program|cellular suicide|programmed cell death by apoptosis|cell suicide|caspase-dependent programmed cell death|apoptotic cell death|type I programmed cell death|apoptotic programmed cell death|signaling (initiator) caspase activity|apoptosis signaling|induction of apoptosis|apoptosis|activation of apoptosis|induction of apoptosis by p53										GO:0006917|GO:0008632	Wikipedia:Apoptosis		biological_process											owl:Class	
GO:0046753	biolink:NamedThing	non-lytic viral release	The exit of a viral particle from a cell that does not involve cell lysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18852												biological_process											owl:Class	
GO:0019076	biolink:NamedThing	viral release from host cell	The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.	got7fsn_ti	viral shedding|viral exit|release of virus from host|virus exit from host cell|viral release											VZ:1076		biological_process											owl:Class	
GO:0018360	biolink:NamedThing	protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine	The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine.	got7fsn_ti	protein-haem P460 linkage via haem P460-bis-L-cysteine-L-lysine										GO:0018384	RESID:AA0271		biological_process											owl:Class	
GO:0046559	biolink:NamedThing	alpha-glucuronidase activity	Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate.	got7fsn_ti	alpha-glucosiduronase activity|alpha-D-glucosiduronate glucuronohydrolase activity											RHEA:20005|EC:3.2.1.139|MetaCyc:3.2.1.139-RXN		molecular_function											owl:Class	
GO:0018116	biolink:NamedThing	peptidyl-lysine adenylylation	The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine.	got7fsn_ti	peptidyl-lysine adenylation											RESID:AA0227		biological_process											owl:Class	
GO:0018205	biolink:NamedThing	peptidyl-lysine modification	The modification of peptidyl-lysine.	got7fsn_ti														biological_process											owl:Class	
GO:0035469	biolink:NamedThing	determination of pancreatic left/right asymmetry	Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.	got7fsn_ti							bf	2010-04-22T10:47:15Z						biological_process											owl:Class	
GO:0106029	biolink:NamedThing	tRNA pseudouridine synthase activity	Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.	got7fsn_ti	tRNA pseudouridine(32) synthase|tRNA pseudouridine(65) synthase|transfer ribonucleate pseudouridine synthetase activity|tRNA pseudouridine(13) synthase|tRNA-pseudouridine synthase activity|tRNA pseudouridine(31) synthase|tRNA pseudouridine(38-40) synthase|tRNA pseudouridylate synthase I activity|tRNA-pseudouridine synthase I activity|tRNA-uridine isomerase activity|tRNA pseudouridine(55) synthase|tRNA pseudouridine(38/39) synthase|tRNA-uridine uracilmutase activity|transfer RNA pseudouridine synthetase activity|Mitochondrial tRNA pseudouridine(27/28) synthase						hjd	2017-06-26T17:37:30Z				EC:5.4.99.42|EC:5.4.99.26|EC:5.4.99.44|RHEA:22376|MetaCyc:TRNA-PSEUDOURIDINE-SYNTHASE-I-RXN|EC:5.4.99.12|EC:5.4.99.45|EC:5.4.99.28|EC:5.4.99.27|EC:5.4.99.25		molecular_function											owl:Class	
GO:0009982	biolink:NamedThing	pseudouridine synthase activity	Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.	got7fsn_ti					Note that this term should not be confused with 'pseudouridylate synthase activity ; GO:0004730', which refers to the formation of free pseudouridine from uracil and ribose-5-phosphate.						GO:0016439	Reactome:R-HSA-6782381|Reactome:R-HSA-6787566|Reactome:R-HSA-6790905|Reactome:R-HSA-8870289|Reactome:R-HSA-6786583		molecular_function											owl:Class	
GO:0097374	biolink:NamedThing	sensory neuron axon guidance	The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.	got7fsn_ti							pr	2012-10-01T10:16:22Z						biological_process											owl:Class	
GO:0007411	biolink:NamedThing	axon guidance	The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.	got7fsn_ti	axon pathfinding|axon chemotaxis|axon growth cone guidance										GO:0008040	Wikipedia:Axon_guidance		biological_process											owl:Class	
GO:0001120	biolink:NamedThing	protein-DNA complex remodeling	The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex.	got7fsn_ti							krc	2010-12-03T04:17:15Z						biological_process											owl:Class	
GO:0071824	biolink:NamedThing	protein-DNA complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex.	got7fsn_ti	DNA-protein complex subunit organization|protein-DNA complex subunit organisation						mah	2010-09-08T10:03:26Z						biological_process											owl:Class	
GO:0018558	biolink:NamedThing	5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity	Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0049		molecular_function											owl:Class	
GO:0098648	biolink:NamedThing	collagen anchoring fibril	A specialised collagen fibril that functions as an anchor, binding to other collagen structures.	got7fsn_ti														cellular_component											owl:Class	
GO:0098644	biolink:NamedThing	complex of collagen trimers	A complex of collagen trimers such as a fibril or collagen network.	got7fsn_ti	Supramolecular collagen assembly|Supramolecular aggregate of collagen													cellular_component											owl:Class	
GO:0106097	biolink:NamedThing	cellular response to ceramide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.	got7fsn_ti							hjd	2018-02-12T19:52:55Z						biological_process											owl:Class	
GO:0071396	biolink:NamedThing	cellular response to lipid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.	got7fsn_ti							mah	2009-12-11T04:37:10Z						biological_process											owl:Class	
GO:0003983	biolink:NamedThing	UTP:glucose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.	got7fsn_ti	uridine diphosphate-D-glucose pyrophosphorylase activity|UTP:alpha-D-glucose-1-phosphate uridylyltransferase activity|uridine diphosphoglucose pyrophosphorylase activity|UDP glucose pyrophosphorylase activity|uridine-diphosphate glucose pyrophosphorylase activity|UDPG pyrophosphorylase activity|UTP-glucose-1-phosphate uridylyltransferase activity|UDPG phosphorylase activity|glucose-1-phosphate uridylyltransferase activity|UDP-glucose diphosphorylase activity|UDP-glucose pyrophosphorylase activity|uridine 5'-diphosphoglucose pyrophosphorylase activity											EC:2.7.7.9|Reactome:R-HSA-70286|RHEA:19889|KEGG_REACTION:R00289|MetaCyc:GLUC1PURIDYLTRANS-RXN		molecular_function											owl:Class	
GO:0051748	biolink:NamedThing	UTP-monosaccharide-1-phosphate uridylyltransferase activity	Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.	got7fsn_ti	UDP-monosaccharide diphosphorylase activity|USP|PsUSP|UDP-sugar pyrophosphorylase activity|UDP-monosaccharide pyrophosphorylase activity											MetaCyc:2.7.7.64-RXN|EC:2.7.7.64|RHEA:13205		molecular_function											owl:Class	
GO:0009496	biolink:NamedThing	plastoquinol--plastocyanin reductase activity	Catalysis of the reaction: 2 H(+)[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H(+)[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane.	got7fsn_ti	cytochrome b6f|plastoquinol-plastocyanin reductase activity|cytochrome b6f complex activity|plastoquinol:oxidized-plastocyanin oxidoreductase activity|plastoquinol/plastocyanin oxidoreductase activity											EC:7.1.1.6|KEGG_REACTION:R03817|MetaCyc:PLASTOQUINOL--PLASTOCYANIN-REDUCTASE-RXN|RHEA:22148		molecular_function											owl:Class	
GO:0032195	biolink:NamedThing	post-lysosomal vacuole	A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.	got7fsn_ti	post-lysosome													cellular_component											owl:Class	
GO:0030139	biolink:NamedThing	endocytic vesicle	A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.	got7fsn_ti	endocytotic vesicle|endocytotic transport vesicle											NIF_Subcellular:sao1362520468		cellular_component											owl:Class	
GO:0008762	biolink:NamedThing	UDP-N-acetylmuramate dehydrogenase activity	Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+.	got7fsn_ti	uridine diphosphoacetylpyruvoylglucosamine reductase activity|uridine diphospho-N-acetylglucosamine-enolpyruvate reductase activity|UDP-N-acetylenolpyruvoylglucosamine reductase activity|MurB reductase|UDP-GlcNAc-enoylpyruvate reductase activity|UDP-N-acetylmuramate:NADP+ oxidoreductase activity|UDP-N-acetylglucosamine-enoylpyruvate reductase activity|uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase activity											MetaCyc:UDPNACETYLMURAMATEDEHYDROG-RXN|RHEA:12248|EC:1.3.1.98		molecular_function											owl:Class	
GO:0090253	biolink:NamedThing	convergent extension involved in imaginal disc-derived wing morphogenesis	The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis.	got7fsn_ti							tb	2010-01-22T11:40:46Z						biological_process											owl:Class	
GO:0009886	biolink:NamedThing	post-embryonic animal morphogenesis	The process, occurring after animal embryonic development, by which anatomical structures are generated and organized.	got7fsn_ti	post-embryonic morphogenesis of an anatomical structure													biological_process											owl:Class	
GO:0046774	biolink:NamedThing	suppression by virus of host intracellular interferon activity	Any viral process that results in the inhibition of interferon activity within the host cell.	got7fsn_ti	suppression by virus of intracellular interferon activity in host|negative regulation by virus of intracellular interferon activity													biological_process											owl:Class	
GO:0030683	biolink:NamedThing	mitigation of host immune response by virus	A process by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	suppression of host extracellular antiviral response by virus|negative regulation by virus of intracellular antiviral response|negative regulation by virus of extracellular antiviral response|evasion by virus of host immune response|evasion or tolerance by virus of host immune response|suppression by virus of host extracellular antiviral response|negative regulation of host intracellular antiviral response by virus|viral inhibition of intracellular antiviral response|mitigation by virus of host immune response|suppression by virus of host intracellular antiviral response|suppression by virus of host immune response|suppression of host intracellular antiviral response by virus|negative regulation of host extracellular antiviral response by virus|inhibition of extracellular antiviral response										GO:0019052|GO:0019053			biological_process											owl:Class	
GO:0044514	biolink:NamedThing	envenomation resulting in positive regulation of G protein-coupled receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism.	got7fsn_ti	envenomation resulting in positive regulation of G-protein coupled receptor activity in other organism						jl	2012-02-26T11:06:15Z						biological_process											owl:Class	
GO:0044513	biolink:NamedThing	envenomation resulting in modulation of G protein-coupled receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of G protein-coupled receptor activity in of the bitten organism.	got7fsn_ti	envenomation resulting in modulation of G-protein coupled receptor activity in other organism						jl	2012-02-26T11:02:17Z						biological_process											owl:Class	
GO:0032879	biolink:NamedThing	regulation of localization	Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.	got7fsn_ti	regulation of localisation													biological_process											owl:Class	
GO:0050789	biolink:NamedThing	regulation of biological process	Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.	got7fsn_ti	regulation of physiological process										GO:0050791			biological_process											owl:Class	
GO:0046525	biolink:NamedThing	xylosylprotein 4-beta-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.	got7fsn_ti	UDP-D-galactose:xylose galactosyltransferase activity|UDP-D-galactose:D-xylose galactosyltransferase activity|UDP-galactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity|uridine diphosphogalactose-xylose galactosyltransferase activity|UDP-galactose:xylose galactosyltransferase activity|galactosyltransferase I activity|UDPgalactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity											EC:2.4.1.133|RHEA:15297|MetaCyc:2.4.1.133-RXN|Reactome:R-HSA-1889981|Reactome:R-HSA-3560804		molecular_function											owl:Class	
GO:0035250	biolink:NamedThing	UDP-galactosyltransferase activity	Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0140404	biolink:NamedThing	effector-mediated modulation of host innate immune response by symbiont	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	effector-triggered modulation of host immune response by symbiont|effector triggered modulation of host immune response by symbiont|effector-dependent modulation of host immune response by symbiont|effector mediated modulation of host immune response by symbiont|effector-mediated modulation of host immunity						pg	2019-12-05T11:38:44Z						biological_process											owl:Class	
GO:0140415	biolink:NamedThing	effector-mediated modulation of host defenses by symbiont	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							pg	2020-01-20T16:46:41Z						biological_process											owl:Class	
GO:0120095	biolink:NamedThing	vacuole-isolation membrane contact site	An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome.	got7fsn_ti	vacuole-phagophore contact site|vacuole-IM contact site|VICS						krc	2017-09-18T20:01:35Z						cellular_component											owl:Class	
GO:0044232	biolink:NamedThing	organelle membrane contact site	A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.	got7fsn_ti	MCS|inter-organelle junction|interorganelle junction	https://github.com/geneontology/go-ontology/issues/18994					jl	2010-01-07T03:44:20Z						cellular_component											owl:Class	
GO:0016576	biolink:NamedThing	histone dephosphorylation	The modification of histones by removal of phosphate groups.	got7fsn_ti														biological_process											owl:Class	
GO:0016570	biolink:NamedThing	histone modification	The covalent alteration of one or more amino acid residues within a histone protein.	got7fsn_ti												Wikipedia:Histone#Histone_modifications_in_chromatin_regulation		biological_process											owl:Class	
GO:0034783	biolink:NamedThing	pivalate-CoA ligase activity	Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP.	got7fsn_ti												UM-BBD_reactionID:r1032		molecular_function											owl:Class	
GO:0016878	biolink:NamedThing	acid-thiol ligase activity	Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti												EC:6.2.1.-		molecular_function											owl:Class	
GO:0046585	biolink:NamedThing	enniatin biosynthetic process	The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.	got7fsn_ti	enniatin biosynthesis|enniatin anabolism|enniatin synthesis|enniatin formation													biological_process											owl:Class	
GO:0017000	biolink:NamedThing	antibiotic biosynthetic process	The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.	got7fsn_ti	antibiotic synthesis|antibiotic formation|antibiotic biosynthesis|antibiotic anabolism													biological_process											owl:Class	
GO:0042985	biolink:NamedThing	negative regulation of amyloid precursor protein biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.	got7fsn_ti	inhibition of amyloid precursor protein biosynthetic process|down regulation of amyloid precursor protein biosynthetic process|negative regulation of amyloid precursor protein biosynthesis|downregulation of amyloid precursor protein biosynthetic process|negative regulation of amyloid precursor protein synthesis|down-regulation of amyloid precursor protein biosynthetic process|negative regulation of amyloid precursor protein formation|negative regulation of APP biosynthetic process|negative regulation of amyloid precursor protein anabolism|negative regulation of APP biosynthesis													biological_process											owl:Class	
GO:0010561	biolink:NamedThing	negative regulation of glycoprotein biosynthetic process	Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	got7fsn_ti														biological_process											owl:Class	
GO:0048640	biolink:NamedThing	negative regulation of developmental growth	Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.	got7fsn_ti	down-regulation of developmental growth|inhibition of developmental growth|downregulation of developmental growth|down regulation of developmental growth													biological_process											owl:Class	
GO:0048638	biolink:NamedThing	regulation of developmental growth	Any process that modulates the frequency, rate or extent of developmental growth.	got7fsn_ti														biological_process											owl:Class	
GO:0051952	biolink:NamedThing	regulation of amine transport	Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0051049	biolink:NamedThing	regulation of transport	Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0042066	biolink:NamedThing	perineurial glial growth	Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons.	got7fsn_ti														biological_process											owl:Class	
GO:0042065	biolink:NamedThing	glial cell growth	Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0035608	biolink:NamedThing	protein deglutamylation	The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.	got7fsn_ti	protein amino acid deglutamylation						bf	2010-11-18T01:04:38Z						biological_process											owl:Class	
GO:0018200	biolink:NamedThing	peptidyl-glutamic acid modification	The modification of peptidyl-glutamic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0042549	biolink:NamedThing	photosystem II stabilization	The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0061485	biolink:NamedThing	memory T cell proliferation	The expansion of a memory T cell population by cell division.	got7fsn_ti							dph	2012-12-04T09:52:54Z						biological_process											owl:Class	
GO:0042098	biolink:NamedThing	T cell proliferation	The expansion of a T cell population by cell division. Follows T cell activation.	got7fsn_ti	T-lymphocyte proliferation|T-cell proliferation|T lymphocyte proliferation										GO:0042111			biological_process											owl:Class	
GO:0002305	biolink:NamedThing	CD8-positive, gamma-delta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	got7fsn_ti	CD8-positive, gamma-delta intraepithelial T-cell differentiation|CD8-positive, gamma-delta intraepithelial T lymphocyte differentiation|CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation|CD8-positive, gamma-delta intraepithelial T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0002304	biolink:NamedThing	gamma-delta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	got7fsn_ti	gamma-delta intraepithelial T lymphocyte differentiation|gamma-delta intraepithelial T-cell differentiation|gamma-delta intraepithelial T-lymphocyte differentiation|gamma-delta intraepithelial T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0016063	biolink:NamedThing	rhodopsin biosynthetic process	The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.	got7fsn_ti	rhodopsin formation|rhodopsin biosynthesis|rhodopsin anabolism|rhodopsin synthesis													biological_process											owl:Class	
GO:0006726	biolink:NamedThing	eye pigment biosynthetic process	The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.	got7fsn_ti	eye pigment anabolism|eye pigment synthesis|eye pigment formation|eye pigment biosynthesis													biological_process											owl:Class	
GO:0016860	biolink:NamedThing	intramolecular oxidoreductase activity	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.	got7fsn_ti	intramolecular oxidoreductase activity, other intramolecular oxidoreductases|intramolecular isomerase activity											EC:5.3.-.-|Reactome:R-HSA-109998		molecular_function											owl:Class	
GO:0060096	biolink:NamedThing	serotonin secretion, neurotransmission	The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter.	got7fsn_ti	serotonin release, neurotransmission													biological_process											owl:Class	
GO:0001820	biolink:NamedThing	serotonin secretion	The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.	got7fsn_ti	5-HT secretion|serotonin release|5-hydroxytryptamine secretion													biological_process											owl:Class	
GO:1990775	biolink:NamedThing	endothelin production	The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.	got7fsn_ti	EDN2 production|endothelin secretion|endothelin-3 production|EDN1 production|endothelin-2 production|EDN3 production|endothelin-1 secretion						sl	2015-06-15T23:13:18Z						biological_process											owl:Class	
GO:0001816	biolink:NamedThing	cytokine production	The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	cytokine secretion|cytokine biosynthetic process|cytokine metabolic process|interleukin production|interferon production|interleukin secretion|interferon secretion	https://github.com/geneontology/go-ontology/issues/19116			Note that this term is intended for use when a gene product is seen to cause apparent increases in intracellular or extracellular cytokine levels, without specific regard as to whether the increase is due to increased biosynthesis, increased secretion of preexisting cytokine molecules, or increased conversion from precursor molecules.						GO:0042032|GO:0042107|GO:0042089|GO:0050663			biological_process											owl:Class	
GO:0009225	biolink:NamedThing	nucleotide-sugar metabolic process	The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti	nucleotide-sugar metabolism	https://github.com/geneontology/go-ontology/issues/14587												biological_process											owl:Class	
GO:0055086	biolink:NamedThing	nucleobase-containing small molecule metabolic process	The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.	got7fsn_ti	nucleobase, nucleoside and nucleotide metabolic process|nucleobase, nucleoside and nucleotide metabolism													biological_process											owl:Class	
GO:0018165	biolink:NamedThing	peptidyl-tyrosine uridylylation	The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase.	got7fsn_ti												RESID:AA0256		biological_process											owl:Class	
GO:0018212	biolink:NamedThing	peptidyl-tyrosine modification	The modification of peptidyl-tyrosine.	got7fsn_ti														biological_process											owl:Class	
GO:2000147	biolink:NamedThing	positive regulation of cell motility	Any process that activates or increases the frequency, rate or extent of cell motility.	got7fsn_ti	positive regulation of movement of a cell|positive regulation of cell movement|positive regulation of cell locomotion						mah	2010-10-01T09:41:30Z						biological_process											owl:Class	
GO:2000145	biolink:NamedThing	regulation of cell motility	Any process that modulates the frequency, rate or extent of cell motility.	got7fsn_ti	regulation of cell locomotion|regulation of cell movement|regulation of movement of a cell						mah	2010-10-01T09:41:21Z						biological_process											owl:Class	
GO:0002164	biolink:NamedThing	larval development	The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.	got7fsn_ti														biological_process											owl:Class	
GO:0009791	biolink:NamedThing	post-embryonic development	The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.	got7fsn_ti														biological_process											owl:Class	
GO:0140103	biolink:NamedThing	catalytic activity, acting on a glycoprotein	Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14225					pg	2017-09-15T19:27:54Z						molecular_function											owl:Class	
GO:0007458	biolink:NamedThing	progression of morphogenetic furrow involved in compound eye morphogenesis	The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc.	got7fsn_ti	progression of morphogenetic furrow during compound eye morphogenesis													biological_process											owl:Class	
GO:0009967	biolink:NamedThing	positive regulation of signal transduction	Any process that activates or increases the frequency, rate or extent of signal transduction.	got7fsn_ti	upregulation of signal transduction|up regulation of signal transduction|stimulation of signal transduction|activation of signal transduction|positive regulation of signaling pathway|up-regulation of signal transduction|positive regulation of signalling pathway										GO:0035468			biological_process											owl:Class	
GO:0022008	biolink:NamedThing	neurogenesis	Generation of cells within the nervous system.	got7fsn_ti	nervous system cell generation|neural cell differentiation											Wikipedia:Neurogenesis		biological_process											owl:Class	
GO:0030154	biolink:NamedThing	cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	got7fsn_ti												Wikipedia:Cellular_differentiation		biological_process											owl:Class	
GO:0060447	biolink:NamedThing	bud outgrowth involved in lung branching	The process in which a region of the lung epithelium initiates an outgrowth.	got7fsn_ti	bud formation involved in lung branching													biological_process											owl:Class	
GO:0060602	biolink:NamedThing	branch elongation of an epithelium	The growth process in which a branch increases in length from its base to its tip.	got7fsn_ti							dph	2009-05-14T02:45:44Z						biological_process											owl:Class	
GO:0033692	biolink:NamedThing	cellular polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell.	got7fsn_ti	cellular glycan biosynthesis|cellular polysaccharide biosynthesis|cellular polysaccharide anabolism|cellular glycan biosynthetic process|cellular polysaccharide synthesis|cellular polysaccharide formation													biological_process											owl:Class	
GO:0034637	biolink:NamedThing	cellular carbohydrate biosynthetic process	The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0035878	biolink:NamedThing	nail development	The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.	got7fsn_ti							bf	2011-05-31T02:30:34Z						biological_process											owl:Class	
GO:0034597	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.	got7fsn_ti	1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity|inositol polyphosphate 4-phosphatase type II activity|phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity											MetaCyc:3.1.3.66-RXN|Reactome:R-HSA-6810410|EC:3.1.3.66		molecular_function											owl:Class	
GO:0034596	biolink:NamedThing	phosphatidylinositol phosphate 4-phosphatase activity	Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate.	got7fsn_ti	PtdIns4P-phosphatase activity|phosphoinositide 4-phosphatase activity|inositol 4-phosphatase|PI(4)P-phosphatase activity|PI4P-phosphatase activity											Reactome:R-HSA-1676133|Reactome:R-HSA-8849969|Reactome:R-HSA-1676124|Reactome:R-HSA-1675988		molecular_function											owl:Class	
GO:0038131	biolink:NamedThing	neuregulin receptor activity	Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	NRG2 receptor activity|NRG1 receptor activity|NRG receptor activity				Consider also annotating to 'ERBB3 signaling pathway ; GO:0038129' and/or 'ERBB4 signaling pathway ; GO:0038130'.		bf	2012-03-30T10:47:11Z						molecular_function											owl:Class	
GO:0004888	biolink:NamedThing	transmembrane signaling receptor activity	Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.	got7fsn_ti	transmembrane signalling receptor activity|transmembrane receptor activity				This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.						GO:0004926|GO:0099600	Reactome:R-HSA-193672		molecular_function											owl:Class	
GO:0051061	biolink:NamedThing	ADP reductase activity	Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.	got7fsn_ti	ADP reduction											MetaCyc:ADPREDUCT-RXN|RHEA:28034		molecular_function											owl:Class	
GO:0004748	biolink:NamedThing	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.	got7fsn_ti	2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity|2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity				When thioredoxin is substituted for glutaredoxin in the reaction, annotate instead to 'ribonucleoside-diphosphate reductase, glutaredoxin disulfide as acceptor ; GO:0036175'.						GO:0016961|GO:0016960|GO:0016959	RHEA:23252|MetaCyc:RIBONUCLEOSIDE-DIP-REDUCTI-RXN|EC:1.17.4.1|Reactome:R-HSA-111804|Reactome:R-HSA-111751		molecular_function											owl:Class	
GO:0098833	biolink:NamedThing	presynaptic endocytic zone	A specialized region of the plasma membrane and underlying cytoplasm which surround the the active zone, into which synaptic vesicle membranes are recycled following exocytosis.  It is especially enriched in endocytic proteins following intense activity.	got7fsn_ti					May be identical to periactive zone?									cellular_component											owl:Class	
GO:0110165	biolink:NamedThing	cellular anatomical entity	A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.	got7fsn_ti							kmv	2019-08-12T18:01:37Z						cellular_component											owl:Class	
GO:0034754	biolink:NamedThing	cellular hormone metabolic process	The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0042445	biolink:NamedThing	hormone metabolic process	The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.	got7fsn_ti	hormone metabolism													biological_process											owl:Class	
GO:0070977	biolink:NamedThing	bone maturation	A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.	got7fsn_ti							mah	2009-10-05T04:35:31Z						biological_process											owl:Class	
GO:0071695	biolink:NamedThing	anatomical structure maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.	got7fsn_ti							mah	2010-03-02T11:43:38Z						biological_process											owl:Class	
GO:2001151	biolink:NamedThing	regulation of renal water transport	Any process that modulates the frequency, rate or extent of renal water transport.	got7fsn_ti							yaf	2011-10-24T11:37:51Z						biological_process											owl:Class	
GO:0071470	biolink:NamedThing	cellular response to osmotic stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti	cellular osmotic stress response|cellular osmotic response						mah	2009-12-18T11:45:33Z						biological_process											owl:Class	
GO:0062197	biolink:NamedThing	cellular response to chemical stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress.	got7fsn_ti							dph	2019-12-10T14:42:03Z						biological_process											owl:Class	
GO:0044790	biolink:NamedThing	negative regulation by host of viral release from host cell	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells.	got7fsn_ti							jl	2013-06-06T10:51:27Z						biological_process											owl:Class	
GO:0044793	biolink:NamedThing	negative regulation by host of viral process	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected.	got7fsn_ti							jl	2013-06-06T11:16:00Z						biological_process											owl:Class	
GO:0046005	biolink:NamedThing	positive regulation of circadian sleep/wake cycle, REM sleep	Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep.	got7fsn_ti	stimulation of circadian sleep/wake cycle, REM sleep|activation of circadian sleep/wake cycle, REM sleep|upregulation of circadian sleep/wake cycle, REM sleep|up regulation of circadian sleep/wake cycle, REM sleep|positive regulation of REM sleep|up-regulation of circadian sleep/wake cycle, REM sleep													biological_process											owl:Class	
GO:0045938	biolink:NamedThing	positive regulation of circadian sleep/wake cycle, sleep	Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.	got7fsn_ti	up-regulation of circadian sleep/wake cycle, sleep|stimulation of circadian sleep/wake cycle, sleep|upregulation of circadian sleep/wake cycle, sleep|positive regulation of sleep|up regulation of circadian sleep/wake cycle, sleep|activation of circadian sleep/wake cycle, sleep													biological_process											owl:Class	
GO:0061103	biolink:NamedThing	carotid body glomus cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.	got7fsn_ti							dph	2010-04-28T10:59:24Z						biological_process											owl:Class	
GO:0061101	biolink:NamedThing	neuroendocrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.	got7fsn_ti							dph	2010-04-28T09:42:20Z						biological_process											owl:Class	
GO:0062036	biolink:NamedThing	sensory perception of hot stimulus	The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.	got7fsn_ti							dph	2018-04-30T13:50:47Z						biological_process											owl:Class	
GO:0050955	biolink:NamedThing	thermoception	The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature).	got7fsn_ti	thermoreception											Wikipedia:Thermoception		biological_process											owl:Class	
GO:0043273	biolink:NamedThing	CTPase activity	Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction.	got7fsn_ti	cytidine triphosphatase activity|CTPase activity, coupled|single-stranded DNA-dependent CTPase activity	https://github.com/geneontology/go-ontology/issues/19078					dph	2015-11-11T13:05:32Z			GO:0061747|GO:0061748			molecular_function											owl:Class	
GO:0017111	biolink:NamedThing	nucleoside-triphosphatase activity	Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.	got7fsn_ti	nucleoside triphosphatase activity|nucleoside triphosphate phosphohydrolase activity|nucleoside 5-triphosphatase activity|nucleoside-5-triphosphate phosphohydrolase activity|unspecific diphosphate phosphohydrolase activity|NTPase activity|nucleoside triphosphate hydrolase activity|apyrase activity											RHEA:23680|Reactome:R-HSA-8851089|Reactome:R-HSA-8850846|MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN|Reactome:R-HSA-8851110|Reactome:R-HSA-8851494|Reactome:R-HSA-8851538|Reactome:R-HSA-8851234		molecular_function											owl:Class	
GO:0023021	biolink:NamedThing	termination of signal transduction	The signaling process in which signal transduction is brought to an end rather than being reversibly modulated.	got7fsn_ti					Note that this term encompasses both the control point when the instruction is given for the process to cease and the actual cessation of the process. A process can persist for some time after that signal that induced the process is withdrawn.			2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0009968	biolink:NamedThing	negative regulation of signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.	got7fsn_ti	inhibition of signal transduction|down regulation of signal transduction|negative regulation of signalling pathway|down-regulation of signal transduction|negative regulation of signaling pathway|downregulation of signal transduction										GO:0035467			biological_process											owl:Class	
GO:0102310	biolink:NamedThing	dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose-forming) activity	Catalysis of the reaction: dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose + NAD(P) <=> dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate + 2 H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-12940		molecular_function											owl:Class	
GO:0016726	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.	got7fsn_ti												EC:1.17.1.-		molecular_function											owl:Class	
GO:0010646	biolink:NamedThing	regulation of cell communication	Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti														biological_process											owl:Class	
GO:0003430	biolink:NamedThing	growth plate cartilage chondrocyte growth	The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another.	got7fsn_ti	growth plate cartilage chondrocyte hypertrophy						dph	2009-12-22T12:29:19Z						biological_process											owl:Class	
GO:0060560	biolink:NamedThing	developmental growth involved in morphogenesis	The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.	got7fsn_ti	differential growth						dph	2009-04-28T08:42:53Z						biological_process											owl:Class	
GO:0051051	biolink:NamedThing	negative regulation of transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	down-regulation of transport|down regulation of transport|inhibition of transport|downregulation of transport													biological_process											owl:Class	
GO:0000714	biolink:NamedThing	meiotic strand displacement	The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis.	got7fsn_ti	meiotic displacement loop processing|meiotic D-loop processing|meiotic D-loop dissociation|meiotic displacement loop dissociation													biological_process											owl:Class	
GO:0000732	biolink:NamedThing	strand displacement	The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.	got7fsn_ti	displacement loop dissociation|D-loop processing|displacement loop processing|D-loop dissociation													biological_process											owl:Class	
GO:0039520	biolink:NamedThing	induction by virus of host autophagy	Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.	got7fsn_ti	positive regulation by virus of host autophagy|activation of host autophagy by virus						bf	2011-06-22T04:24:47Z				VZ:846		biological_process											owl:Class	
GO:0039519	biolink:NamedThing	modulation by virus of host autophagy	Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host.	got7fsn_ti	regulation by virus of host autophagy						bf	2011-06-22T04:19:19Z						biological_process											owl:Class	
GO:0002472	biolink:NamedThing	macrophage antigen processing and presentation	The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0019882	biolink:NamedThing	antigen processing and presentation	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	got7fsn_ti	antigen presentation|antigen processing										GO:0030333	Wikipedia:Antigen_presentation		biological_process											owl:Class	
GO:0010326	biolink:NamedThing	methionine-oxo-acid transaminase activity	Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid.	got7fsn_ti												MetaCyc:RXN-2201		molecular_function											owl:Class	
GO:0046540	biolink:NamedThing	U4/U6 x U5 tri-snRNP complex	A ribonucleoprotein complex that is formed by the association of the U4/U6 and U5 snRNPs.	got7fsn_ti	U4/U6.U5 snRNP complex													cellular_component											owl:Class	
GO:0097526	biolink:NamedThing	spliceosomal tri-snRNP complex	A spliceosomal snRNP complex that is formed by the association of the U4/U6 (or U4atac/U6atac) snRNP with the U5 snRNP.	got7fsn_ti							pr	2013-10-18T15:58:47Z						cellular_component											owl:Class	
GO:0016256	biolink:NamedThing	N-glycan processing to lysosome	The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.	got7fsn_ti														biological_process											owl:Class	
GO:0006491	biolink:NamedThing	N-glycan processing	The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.	got7fsn_ti	N-linked glycoprotein maturation|glycoprotein trimming involved in glycoprotein maturation										GO:0006492			biological_process											owl:Class	
GO:0005937	biolink:NamedThing	mating projection	The projection formed by unicellular fungi in response to mating pheromone.	got7fsn_ti	conjugation tube|shmoo													cellular_component											owl:Class	
GO:0120025	biolink:NamedThing	plasma membrane bounded cell projection	A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13193					krc	2017-03-21T17:26:07Z						cellular_component											owl:Class	
GO:0102599	biolink:NamedThing	cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity	Catalysis of the reaction: beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-beta-amyrin + H2O + NAD(P).	got7fsn_ti												MetaCyc:RXN-15383		molecular_function											owl:Class	
GO:0035136	biolink:NamedThing	forelimb morphogenesis	The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.	got7fsn_ti	arm morphogenesis										GO:0035140			biological_process											owl:Class	
GO:0047238	biolink:NamedThing	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP.	got7fsn_ti	UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyltransferase II activity|glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity|chondroitin synthase activity|UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity											Reactome:R-HSA-1971482|Reactome:R-HSA-9632033|Reactome:R-HSA-1971487|EC:2.4.1.175|Reactome:R-HSA-3595176|MetaCyc:2.4.1.175-RXN		molecular_function											owl:Class	
GO:0008376	biolink:NamedThing	acetylgalactosaminyltransferase activity	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide.	got7fsn_ti	GalNAc transferase activity											Reactome:R-HSA-8931648|Reactome:R-HSA-8855954|Reactome:R-HSA-9605700		molecular_function											owl:Class	
GO:0016615	biolink:NamedThing	malate dehydrogenase activity	Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.	got7fsn_ti														molecular_function											owl:Class	
GO:0033539	biolink:NamedThing	fatty acid beta-oxidation using acyl-CoA dehydrogenase	A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	got7fsn_ti												MetaCyc:FAO-PWY		biological_process											owl:Class	
GO:0006635	biolink:NamedThing	fatty acid beta-oxidation	A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	got7fsn_ti														biological_process											owl:Class	
GO:0033925	biolink:NamedThing	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.	got7fsn_ti	mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity|endo-beta-N-acetylglucosaminidase D activity|endo-beta-N-acetylglucosaminidase H activity|glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity|endo-beta-N-acetylglucosaminidase L activity|endo-N-acetyl-beta-glucosaminidase activity|endo-beta-N-acetylglucosaminidase activity|endo-N-acetyl-beta-D-glucosaminidase activity|mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity|endoglycosidase H activity|glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity|N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity|endo-beta-N-acetylglucosaminidase F activity|endoglycosidase S activity|endo-beta-(1->4)-N-acetylglucosaminidase activity|di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity|endo-beta-acetylglucosaminidase activity											EC:3.2.1.96|MetaCyc:3.2.1.96-RXN|Reactome:R-HSA-8853379		molecular_function											owl:Class	
GO:0010837	biolink:NamedThing	regulation of keratinocyte proliferation	Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0050678	biolink:NamedThing	regulation of epithelial cell proliferation	Any process that modulates the frequency, rate or extent of epithelial cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0070056	biolink:NamedThing	prospore membrane leading edge	The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.	got7fsn_ti	forespore membrane leading edge													cellular_component											owl:Class	
GO:0016020	biolink:NamedThing	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.	got7fsn_ti	region of membrane|whole membrane|membrane region							2014-03-06T11:37:54Z			GO:0098589|GO:0098805	Wikipedia:Biological_membrane		cellular_component											owl:Class	
GO:0090697	biolink:NamedThing	post-embryonic plant organ morphogenesis	Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti							tb	2016-08-25T17:04:35Z						biological_process											owl:Class	
GO:0090698	biolink:NamedThing	post-embryonic plant morphogenesis	The process, occurring after plant embryonic development, by which anatomical structures are generated and organized.	got7fsn_ti							tb	2016-08-25T17:08:33Z						biological_process											owl:Class	
GO:0061826	biolink:NamedThing	podosome ring	The ring structure surrounding the podosome core, containing proteins such as vinculin and talin.	got7fsn_ti							dph	2017-01-14T14:44:53Z						cellular_component											owl:Class	
GO:0051449	biolink:NamedThing	thyrotropin-releasing hormone binding	Binding to thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system.	got7fsn_ti	thyrotropin releasing hormone binding													molecular_function											owl:Class	
GO:0017046	biolink:NamedThing	peptide hormone binding	Binding to a peptide with hormonal activity in animals.	got7fsn_ti	polypeptide hormone binding													molecular_function											owl:Class	
GO:0015347	biolink:NamedThing	sodium-independent organic anion transmembrane transporter activity	Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner.	got7fsn_ti												Reactome:R-HSA-879594|Reactome:R-HSA-9661723|Reactome:R-HSA-9661397|Reactome:R-HSA-879562|Reactome:R-HSA-9661446|Reactome:R-HSA-561059|Reactome:R-HSA-879584|Reactome:R-HSA-9661799		molecular_function											owl:Class	
GO:0008514	biolink:NamedThing	organic anion transmembrane transporter activity	Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.	got7fsn_ti												Reactome:R-HSA-2142859		molecular_function											owl:Class	
GO:1900053	biolink:NamedThing	negative regulation of retinoic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process.	got7fsn_ti	downregulation of retinoic acid anabolic process|inhibition of retinoic acid biosynthetic process|down regulation of retinoic acid biosynthetic process|down-regulation of retinoic acid biosynthetic process|negative regulation of retinoic acid anabolic process|downregulation of retinoic acid biosynthetic process|down regulation of retinoic acid anabolic process|down-regulation of retinoic acid anabolic process|inhibition of retinoic acid anabolic process						yaf	2012-01-20T09:55:49Z						biological_process											owl:Class	
GO:0046137	biolink:NamedThing	negative regulation of vitamin metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	got7fsn_ti	inhibition of vitamin metabolic process|down-regulation of vitamin metabolic process|down regulation of vitamin metabolic process|negative regulation of vitamin metabolism|downregulation of vitamin metabolic process													biological_process											owl:Class	
GO:0103071	biolink:NamedThing	2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA lyase activity	Catalysis of the reaction: a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA <=> formyl-CoA + a 2-methyl branched 2,3,4-saturated fatty aldehyde.	got7fsn_ti												MetaCyc:RXN66-471		molecular_function											owl:Class	
GO:0016830	biolink:NamedThing	carbon-carbon lyase activity	Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.	got7fsn_ti	other carbon-carbon lyase activity											Reactome:R-HSA-389611|EC:4.1.-.-		molecular_function											owl:Class	
GO:0008649	biolink:NamedThing	rRNA methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0008173	biolink:NamedThing	RNA methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.	got7fsn_ti					Note that the methyl donor is usually S-adenosyl-L-methionine, but there is at least one exception (see GO:0030698).							Reactome:R-HSA-191784		molecular_function											owl:Class	
GO:0008738	biolink:NamedThing	L-fuculose-phosphate aldolase activity	Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate.	got7fsn_ti	L-fuculose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)|fuculose aldolase activity|L-fuculose 1-phosphate aldolase activity|L-fuculose-1-phosphate lactaldehyde-lyase activity											MetaCyc:FUCPALDOL-RXN|RHEA:12933|EC:4.1.2.17|KEGG_REACTION:R02262		molecular_function											owl:Class	
GO:0070976	biolink:NamedThing	TIR domain binding	Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.	got7fsn_ti	Toll-Interleukin receptor domain binding						mah	2009-10-02T01:17:29Z						molecular_function											owl:Class	
GO:0047685	biolink:NamedThing	amine sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.	got7fsn_ti	arylamine sulfotransferase activity|3'-phosphoadenylyl-sulfate:amine N-sulfotransferase activity|amine N-sulfotransferase activity|amine sulphotransferase activity											EC:2.8.2.3|MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN|RHEA:24136		molecular_function											owl:Class	
GO:0008146	biolink:NamedThing	sulfotransferase activity	Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.	got7fsn_ti	sulphotransferase activity											Reactome:R-HSA-2022061|EC:2.8.2.-|Reactome:R-HSA-176588|Reactome:R-HSA-176669|Reactome:R-HSA-176604		molecular_function											owl:Class	
GO:0016213	biolink:NamedThing	linoleoyl-CoA desaturase activity	Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.	got7fsn_ti	fatty acid delta6-desaturase activity|linoleoyl CoA desaturase activity|delta6-desaturase activity|linoleate desaturase activity|linoleic desaturase activity|long-chain fatty acid delta(6)-desaturase activity|fatty acid delta(6)-desaturase activity|delta(6)-fatty acyl-CoA desaturase activity|delta6-acyl CoA desaturase activity|delta6-fatty acyl-CoA desaturase activity|long-chain fatty acid delta6-desaturase activity|linoleoyl-coenzyme A desaturase activity|delta(6)-desaturase activity|linoleic acid desaturase activity|delta(6)-acyl CoA desaturase activity|fatty acid 6-desaturase activity				Note that this function was formerly EC:1.14.99.25.							Reactome:R-HSA-2046084|EC:1.14.19.3|Reactome:R-HSA-2046096|MetaCyc:1.14.19.3-RXN|RHEA:22196|Reactome:R-HSA-2046097|Reactome:R-HSA-2046099		molecular_function											owl:Class	
GO:0016215	biolink:NamedThing	acyl-CoA desaturase activity	Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O.	got7fsn_ti	CoA desaturase activity	https://github.com/geneontology/go-ontology/issues/21108												molecular_function											owl:Class	
GO:0021680	biolink:NamedThing	cerebellar Purkinje cell layer development	The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	got7fsn_ti														biological_process											owl:Class	
GO:0009355	biolink:NamedThing	DNA polymerase V complex	A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0042575	biolink:NamedThing	DNA polymerase complex	A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.	got7fsn_ti														cellular_component											owl:Class	
GO:0031381	biolink:NamedThing	viral RNA-directed RNA polymerase complex	A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus.	got7fsn_ti														cellular_component											owl:Class	
GO:0031379	biolink:NamedThing	RNA-directed RNA polymerase complex	A protein complex that possesses RNA-directed RNA polymerase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0001634	biolink:NamedThing	pituitary adenylate cyclase-activating polypeptide receptor activity	A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide.	got7fsn_ti	pituitary adenylate cyclase-activating polypeptide receptor activity|pituitary adenylate cyclase activating polypeptide receptor|pituitary adenylate cyclase activating protein receptor activity|PACAP receptor|pituitary adenylate cyclase-activating peptide receptor activity|pituitary adenylyl cyclase activating protein receptor activity										GO:0016522			molecular_function											owl:Class	
GO:0004930	biolink:NamedThing	G protein-coupled receptor activity	Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	SREB receptor|G protein linked receptor activity|G-protein coupled receptor activity|orphan GPCR activity|G-protein linked receptor activity|RDC1 receptor activity|orphan G-protein coupled receptor activity|super conserved receptor expressed in brain receptor activity|Mas proto-oncogene receptor activity|Epstein-Barr Virus-induced receptor activity|ligand-dependent GPCR activity|G protein coupled receptor activity|EBV-induced receptor|GPCR activity|G-protein coupled receptor activity, unknown ligand|orphan G protein coupled receptor activity|receptor activity, G-protein coupled										GO:0001625|GO:0001623|GO:0016526|GO:0001624|GO:0001622	Wikipedia:GPCR|Reactome:R-HSA-167408|Reactome:R-HSA-114558|Reactome:R-HSA-114552		molecular_function											owl:Class	
GO:0042297	biolink:NamedThing	vocal learning	A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.	got7fsn_ti					Examples include language learning by human infants and song learning in zebra finches.							Wikipedia:Vocal_learning		biological_process											owl:Class	
GO:0031223	biolink:NamedThing	auditory behavior	The behavior of an organism in response to a sound.	got7fsn_ti	behavioural response to sound|behavioral response to sound|auditory behaviour													biological_process											owl:Class	
GO:0044741	biolink:NamedThing	envenomation resulting in negative regulation of sensory perception of pain in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism.	got7fsn_ti	envenomation resulting in inhibition of sensory perception of pain in other organism						jl	2012-11-07T14:02:14Z						biological_process											owl:Class	
GO:0044742	biolink:NamedThing	envenomation resulting in modulation of sensory perception of pain in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism.	got7fsn_ti	envenomation resulting in regulation of sensory perception of pain in other organism						jl	2012-11-07T14:26:38Z						biological_process											owl:Class	
GO:0090225	biolink:NamedThing	regulation of spindle density	Any process that modulates the number of microtubules in a given region of the spindle.	got7fsn_ti							tb	2010-01-13T11:24:53Z						biological_process											owl:Class	
GO:0090224	biolink:NamedThing	regulation of spindle organization	Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle.	got7fsn_ti	regulation of spindle organisation						tb	2010-01-13T11:04:53Z						biological_process											owl:Class	
GO:0003419	biolink:NamedThing	growth plate cartilage chondrocyte proliferation	The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.	got7fsn_ti							dph	2009-12-22T09:02:51Z						biological_process											owl:Class	
GO:0008283	biolink:NamedThing	cell population proliferation	The multiplication or reproduction of cells, resulting in the expansion of a cell population.	got7fsn_ti	cell proliferation				This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms.									biological_process											owl:Class	
GO:0030445	biolink:NamedThing	yeast-form cell wall	The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.	got7fsn_ti					See also the Fungal Anatomy Ontology term 'vegetative cell ; FAO:0000032'.									cellular_component											owl:Class	
GO:0009277	biolink:NamedThing	fungal-type cell wall	A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.	got7fsn_ti	chitin-containing cell wall|beta-glucan-containing cell wall|chitin- and beta-glucan-containing cell wall													cellular_component											owl:Class	
GO:0051500	biolink:NamedThing	D-tyrosyl-tRNA(Tyr) deacylase activity	Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0051499	biolink:NamedThing	D-aminoacyl-tRNA deacylase activity	Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA.	got7fsn_ti												EC:3.1.1.96|MetaCyc:RXN-15041|RHEA:13953		molecular_function											owl:Class	
GO:0033592	biolink:NamedThing	RNA strand annealing activity	An activity that facilitates the formation of a complementary double-stranded RNA molecule.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/2161												molecular_function											owl:Class	
GO:0003727	biolink:NamedThing	single-stranded RNA binding	Binding to single-stranded RNA.	got7fsn_ti	ssRNA binding										GO:0003728			molecular_function											owl:Class	
GO:0097668	biolink:NamedThing	SCF-Saf1/Pof9 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe).	got7fsn_ti							pr	2014-10-06T10:28:30Z						cellular_component											owl:Class	
GO:0048136	biolink:NamedThing	male germ-line cyst formation	Formation of a group of interconnected cells derived from a single male gonial founder cell.	got7fsn_ti	male germline cyst formation													biological_process											owl:Class	
GO:0048134	biolink:NamedThing	germ-line cyst formation	Formation of a group of interconnected cells derived from a single gonial founder cell.	got7fsn_ti	germline cyst formation													biological_process											owl:Class	
GO:0015233	biolink:NamedThing	pantothenate transmembrane transporter activity	Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	got7fsn_ti	vitamin B5 transmembrane transporter activity|pantothenate transporter activity													molecular_function											owl:Class	
GO:0090482	biolink:NamedThing	vitamin transmembrane transporter activity	Enables the transfer of a vitamin from one side of a membrane to the other.	got7fsn_ti	vitamin or cofactor transporter activity|vitamin transporter activity						tb	2012-10-02T16:50:50Z			GO:0051183			molecular_function											owl:Class	
GO:0004342	biolink:NamedThing	glucosamine-6-phosphate deaminase activity	Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+).	got7fsn_ti	phosphoglucosaminisomerase activity|glucosaminephosphate isomerase|glucosamine-6-phosphate isomerase activity|phosphoglucosamine isomerase activity|aminodeoxyglucosephosphate isomerase activity|GlcN6P deaminase activity|2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)|glucosamine phosphate deaminase activity				Note that this function was formerly EC:5.3.1.10.							Reactome:R-HSA-6799604|MetaCyc:GLUCOSAMINE-6-P-DEAMIN-RXN|RHEA:12172|EC:3.5.99.6|KEGG_REACTION:R00765		molecular_function											owl:Class	
GO:0019239	biolink:NamedThing	deaminase activity	Catalysis of the removal of an amino group from a substrate, producing a substituted or nonsubstituted ammonia (NH3/NH2R).	got7fsn_ti												Reactome:R-HSA-9014641		molecular_function											owl:Class	
GO:0043629	biolink:NamedThing	ncRNA polyadenylation	The enzymatic addition of a sequence of adenylyl residues at the 3' end of a non-coding RNA (ncRNA) molecule. In eukaryotes, substrates include nuclear non-coding RNAs such as precursors and a variety of incorrectly processed forms of snRNAs, snoRNAs, rRNAs, and tRNAs, as well as discarded RNA fragments which have been removed from ncRNA primary transcripts. Polyadenylation of precursors is often linked to termination of transcription, but polyadenylation of RNAs targeted for degradation may also occur post-transcriptionally. This polyadenylation is important both for 3'-end processing to produce mature ncRNA species and also for targeting incorrectly processed or discarded RNA molecules for degradation.	got7fsn_ti	non-coding RNA polyadenylation													biological_process											owl:Class	
GO:0043631	biolink:NamedThing	RNA polyadenylation	The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0001974	biolink:NamedThing	blood vessel remodeling	The reorganization or renovation of existing blood vessels.	got7fsn_ti														biological_process											owl:Class	
GO:0048771	biolink:NamedThing	tissue remodeling	The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.	got7fsn_ti														biological_process											owl:Class	
GO:0008883	biolink:NamedThing	glutamyl-tRNA reductase activity	Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.	got7fsn_ti	L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming)											EC:1.2.1.70|KEGG_REACTION:R04109|RHEA:12344|MetaCyc:GLUTRNAREDUCT-RXN		molecular_function											owl:Class	
GO:0140101	biolink:NamedThing	catalytic activity, acting on a tRNA	Catalytic activity that acts to modify a tRNA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14225					pg	2017-09-15T18:41:41Z						molecular_function											owl:Class	
GO:1902491	biolink:NamedThing	negative regulation of sperm capacitation	Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation.	got7fsn_ti	down regulation of sperm activation|negative regulation of sperm activation|downregulation of sperm capacitation|down-regulation of sperm capacitation|down regulation of sperm capacitation|inhibition of sperm activation|down-regulation of sperm activation|inhibition of sperm capacitation|downregulation of sperm activation						hjd	2013-11-12T21:17:12Z						biological_process											owl:Class	
GO:1990530	biolink:NamedThing	Cdc50p-Drs2p complex	A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome.	got7fsn_ti							rb	2014-11-06T01:29:31Z						cellular_component											owl:Class	
GO:1990531	biolink:NamedThing	phospholipid-translocating ATPase complex	A protein complex that functions as a phospholipid-translocating P-Type ATPase.	got7fsn_ti	CRF1-DNF3 complex|phospholipid flippase complex|CDC50-DRS2 complex|DNF3-CRF1 complex|APLT complex|DRS2-CDC50 complex|Dnf1-Lem3 complex|aminophospholipid translocase complex|Dnf2-Lem3 complex|Lem3-Dnf1 complex|P4-ATPase complex|Lem3p-Dnf1p complex						rb	2014-11-06T22:33:25Z						cellular_component											owl:Class	
GO:0047287	biolink:NamedThing	lactosylceramide alpha-2,6-N-sialyltransferase activity	Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide + CMP.	got7fsn_ti	CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase activity|CMP-sialic acid:lactosylceramide sialyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase|CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activity|CMP-acetylneuraminate-lactosylceramide-sialyltransferase											EC:2.4.99.11|MetaCyc:2.4.99.11-RXN|RHEA:21552		molecular_function											owl:Class	
GO:0008373	biolink:NamedThing	sialyltransferase activity	Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.	got7fsn_ti												Reactome:R-HSA-9697018|Reactome:R-HSA-981814|Reactome:R-HSA-9683769|Reactome:R-HSA-9694718		molecular_function											owl:Class	
GO:0061526	biolink:NamedThing	acetylcholine secretion	The regulated release of acetylcholine by a cell.	got7fsn_ti							dph	2013-06-21T15:40:39Z						biological_process											owl:Class	
GO:0003219	biolink:NamedThing	cardiac right ventricle formation	The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.	got7fsn_ti							dph	2009-10-13T09:55:38Z						biological_process											owl:Class	
GO:0003211	biolink:NamedThing	cardiac ventricle formation	The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.	got7fsn_ti							dph	2009-10-13T09:46:27Z						biological_process											owl:Class	
GO:0036343	biolink:NamedThing	psychomotor behavior	The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument.	got7fsn_ti							bf	2012-09-11T14:32:06Z						biological_process											owl:Class	
GO:0061744	biolink:NamedThing	motor behavior	The specific neuromuscular movement of a single organism in response to external or internal stimuli.	got7fsn_ti							dph	2015-11-09T12:43:11Z						biological_process											owl:Class	
GO:0050345	biolink:NamedThing	trans-epoxysuccinate hydrolase activity	Catalysis of the reaction: trans-2,3-epoxysuccinate + H(2)O = (2R,3S)-tartrate.	got7fsn_ti	tartrate epoxydase activity|trans-2,3-epoxysuccinate hydrolase activity|trans-epoxysuccinate hydratase activity											RHEA:20740|EC:3.3.2.4|KEGG_REACTION:R02547|MetaCyc:TRANS-EPOXYSUCCINATE-HYDROLASE-RXN		molecular_function											owl:Class	
GO:0016803	biolink:NamedThing	ether hydrolase activity	Catalysis of the hydrolysis of an ether bond, -O-.	got7fsn_ti												Reactome:R-HSA-8874435|EC:3.3.2.-		molecular_function											owl:Class	
GO:0046726	biolink:NamedThing	positive regulation by virus of viral protein levels in host cell	Any process where the infecting virus increases the levels of viral proteins in a cell.	got7fsn_ti	activation of viral protein levels in host cell|up regulation of viral protein levels in host cell|upregulation of viral protein levels in host cell|up-regulation of viral protein levels in host cell|positive regulation of viral protein levels|stimulation of viral protein levels in host cell													biological_process											owl:Class	
GO:0046719	biolink:NamedThing	regulation by virus of viral protein levels in host cell	Any virus-mediated process that modulates the levels of viral proteins in a cell.	got7fsn_ti	regulation of viral protein levels													biological_process											owl:Class	
GO:0008119	biolink:NamedThing	thiopurine S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.	got7fsn_ti	thiopurine methyltransferase activity|mercaptopurine methyltransferase activity|TPMT|6-thiopurine transmethylase activity|S-adenosyl-L-methionine:thiopurine S-methyltransferase activity											Reactome:R-HSA-5603379|MetaCyc:THIOPURINE-S-METHYLTRANSFERASE-RXN|Reactome:R-HSA-158609|EC:2.1.1.67		molecular_function											owl:Class	
GO:0008172	biolink:NamedThing	S-methyltransferase activity	Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.	got7fsn_ti												Reactome:R-HSA-209821|EC:2.1.1.-		molecular_function											owl:Class	
GO:0001548	biolink:NamedThing	follicular fluid formation in ovarian follicle antrum	The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis.	got7fsn_ti	ovarian follicle antrum/follicular fluid biosynthesis|ovarian follicle antrum/follicular fluid formation													biological_process											owl:Class	
GO:0022602	biolink:NamedThing	ovulation cycle process	A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.	got7fsn_ti	estrous cycle process|menstrual cycle process													biological_process											owl:Class	
GO:0008587	biolink:NamedThing	imaginal disc-derived wing margin morphogenesis	The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.	got7fsn_ti	wing margin morphogenesis				See also the fly_anatomy.ontology term 'wing margin ; FBbt:00005378'.									biological_process											owl:Class	
GO:0046309	biolink:NamedThing	1,3-dichloro-2-propanol biosynthetic process	The chemical reactions and pathways resulting in the formation of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic.	got7fsn_ti	1,3-dichloro-2-propanol biosynthesis|1,3-dichloro-2-propanol synthesis|1,3-dichloro-2-propanol anabolism|1,3-dichloro-2-propanol formation													biological_process											owl:Class	
GO:0033268	biolink:NamedThing	node of Ranvier	An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.	got7fsn_ti	node of Ranvier axon											NIF_Subcellular:birnlex_1152_2|Wikipedia:Nodes_of_Ranvier		cellular_component											owl:Class	
GO:0010218	biolink:NamedThing	response to far red light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti	response to far red light stimulus													biological_process											owl:Class	
GO:0030879	biolink:NamedThing	mammary gland development	The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.	got7fsn_ti	mammogenesis													biological_process											owl:Class	
GO:0031352	biolink:NamedThing	intrinsic component of plastid inner membrane	The component of the plastid inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to plastid inner membrane													cellular_component											owl:Class	
GO:0031350	biolink:NamedThing	intrinsic component of plastid membrane	The component of the plastid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to plastid membrane													cellular_component											owl:Class	
GO:0035124	biolink:NamedThing	embryonic caudal fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0035143	biolink:NamedThing	caudal fin morphogenesis	The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0102978	biolink:NamedThing	furaneol oxidoreductase activity	Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP <=> 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+.	got7fsn_ti												EC:1.3.1.105|RHEA:39111|MetaCyc:RXN-9563		molecular_function											owl:Class	
GO:0075510	biolink:NamedThing	macropinocytosis involved in viral entry into host cell	Any macropinocytosis that is involved in the uptake of a virus into a host cell.	got7fsn_ti	viral entry into host cell via macropinocytosis						jl	2011-07-27T11:24:59Z				VZ:800		biological_process											owl:Class	
GO:0075509	biolink:NamedThing	endocytosis involved in viral entry into host cell	Any endocytosis that is involved in the uptake of a virus into a host cell.	got7fsn_ti	virus endocytosis by host|viral penetration via endocytosis followed by endosome disruption|viral entry into host cell via endocytosis						jl	2011-07-27T11:06:34Z				VZ:977		biological_process											owl:Class	
GO:0050904	biolink:NamedThing	diapedesis	The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.	got7fsn_ti					Note that the term diapedesis, although sometimes used as a direct synonym for cellular extravasation, is used here for the specific final step of the process, in concordance with recent reviews of the topic.									biological_process											owl:Class	
GO:0050900	biolink:NamedThing	leukocyte migration	The movement of a leukocyte within or between different tissues and organs of the body.	got7fsn_ti	immune cell trafficking|leucocyte migration|leukocyte trafficking|leucocyte trafficking|immune cell migration													biological_process											owl:Class	
GO:0034983	biolink:NamedThing	peptidyl-lysine deacetylation	The removal of an acetyl group from an acetylated lysine residue in a peptide or protein.	got7fsn_ti	protein lysine acetylation													biological_process											owl:Class	
GO:0034689	biolink:NamedThing	integrin alphaX-beta2 complex	An integrin complex that comprises one alphaX subunit and one beta2 subunit.	got7fsn_ti	alphaX-beta2 integrin complex|Itgax-Itgb2 complex													cellular_component											owl:Class	
GO:0008305	biolink:NamedThing	integrin complex	A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.	got7fsn_ti	laminin receptor protein													cellular_component											owl:Class	
GO:0090174	biolink:NamedThing	organelle membrane fusion	The joining of two lipid bilayers to form a single organelle membrane.	got7fsn_ti							tb	2009-12-11T11:44:58Z						biological_process											owl:Class	
GO:0048284	biolink:NamedThing	organelle fusion	The creation of a single organelle from two or more organelles.	got7fsn_ti														biological_process											owl:Class	
GO:0022608	biolink:NamedThing	multicellular organism adhesion	The attachment of a multicellular organism to a substrate or other organism.	got7fsn_ti														biological_process											owl:Class	
GO:0032501	biolink:NamedThing	multicellular organismal process	Any biological process, occurring at the level of a multicellular organism, pertinent to its function.	got7fsn_ti	single-multicellular organism process|organismal physiological process						jl	2012-09-19T16:07:47Z			GO:0050874|GO:0044707			biological_process											owl:Class	
GO:0044392	biolink:NamedThing	peptidyl-lysine malonylation	The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.	got7fsn_ti	lysine malonylation						bf	2011-12-12T09:31:42Z				RESID:AA0568		biological_process											owl:Class	
GO:0044394	biolink:NamedThing	protein malonylation	The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.	got7fsn_ti							bf	2011-12-12T09:26:37Z						biological_process											owl:Class	
GO:0102060	biolink:NamedThing	endo-alpha-bergamotene synthase activity	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (-)-endo-alpha-bergamotene + diphosphoric acid.	got7fsn_ti	endo-alpha-bergamontene synthase activity											RHEA:30471|MetaCyc:RXN-10482|EC:4.2.3.54		molecular_function											owl:Class	
GO:0008033	biolink:NamedThing	tRNA processing	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.	got7fsn_ti	tRNA maturation													biological_process											owl:Class	
GO:0006399	biolink:NamedThing	tRNA metabolic process	The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established.	got7fsn_ti	tRNA metabolism													biological_process											owl:Class	
GO:0046810	biolink:NamedThing	host cell extracellular matrix binding	Binding to the extracellular matrix of a host cell.	got7fsn_ti														molecular_function											owl:Class	
GO:0050840	biolink:NamedThing	extracellular matrix binding	Binding to a component of the extracellular matrix.	got7fsn_ti	adhesive extracellular matrix constituent|extracellular matrix constituent binding													molecular_function											owl:Class	
GO:0003953	biolink:NamedThing	NAD+ nucleosidase activity	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose.	got7fsn_ti	NAD nucleosidase activity											Reactome:R-HSA-8938076|Reactome:R-HSA-8870346|RHEA:16301		molecular_function											owl:Class	
GO:0016799	biolink:NamedThing	hydrolase activity, hydrolyzing N-glycosyl compounds	Catalysis of the hydrolysis of any N-glycosyl bond.	got7fsn_ti												EC:3.2.2.-		molecular_function											owl:Class	
GO:0042015	biolink:NamedThing	interleukin-20 binding	Binding to interleukin-20.	got7fsn_ti	IL-20 binding													molecular_function											owl:Class	
GO:0019955	biolink:NamedThing	cytokine binding	Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.	got7fsn_ti	interleukin binding|IL binding										GO:0019965			molecular_function											owl:Class	
GO:0005594	biolink:NamedThing	collagen type IX trimer	A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0005593	biolink:NamedThing	FACIT collagen trimer	A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences.	got7fsn_ti					The acronym FACIT stands for fibril-associated collagen with interrupted triple helix.							Wikipedia:FACIT_collagen		cellular_component											owl:Class	
GO:0046786	biolink:NamedThing	viral replication complex formation and maintenance	The process of organizing and assembling viral replication proteins in preparation for viral replication.	got7fsn_ti														biological_process											owl:Class	
GO:0097400	biolink:NamedThing	interleukin-17-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-17 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-17-mediated signalling pathway|IL-17-mediated signalling pathway|IL-17-mediated signaling pathway						pr	2012-10-23T13:30:03Z						biological_process											owl:Class	
GO:0019221	biolink:NamedThing	cytokine-mediated signaling pathway	A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	cytokine mediated signalling pathway|cytokine and chemokine mediated signaling pathway													biological_process											owl:Class	
GO:0043291	biolink:NamedThing	RAVE complex	A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme.	got7fsn_ti	regulator of the (H+)-ATPase of the vacuolar and endosomal membranes													cellular_component											owl:Class	
GO:0061263	biolink:NamedThing	mesonephric glomerular mesangial cell development	The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-08-30T02:52:55Z						biological_process											owl:Class	
GO:0072144	biolink:NamedThing	glomerular mesangial cell development	The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure.	got7fsn_ti							mah	2010-02-24T01:53:13Z						biological_process											owl:Class	
GO:0071788	biolink:NamedThing	endoplasmic reticulum tubular network maintenance	The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.	got7fsn_ti	ER tubular network maintenance						mah	2010-09-01T01:55:06Z						biological_process											owl:Class	
GO:0043954	biolink:NamedThing	cellular component maintenance	The organization process that preserves a cellular component in a stable functional or structural state.	got7fsn_ti	cellular component maintenance at cellular level										GO:0071956			biological_process											owl:Class	
GO:0018733	biolink:NamedThing	3,4-dihydrocoumarin hydrolase activity	Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate.	got7fsn_ti												UM-BBD_reactionID:r0419|EC:3.1.1.35		molecular_function											owl:Class	
GO:0043027	biolink:NamedThing	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.	got7fsn_ti	caspase inhibitor activity													molecular_function											owl:Class	
GO:0043028	biolink:NamedThing	cysteine-type endopeptidase regulator activity involved in apoptotic process	Binds to and modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process.	got7fsn_ti	caspase regulator activity													molecular_function											owl:Class	
GO:0050708	biolink:NamedThing	regulation of protein secretion	Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0051223	biolink:NamedThing	regulation of protein transport	Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0050778	biolink:NamedThing	positive regulation of immune response	Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.	got7fsn_ti	upregulation of immune response|stimulation of immune response|up-regulation of immune response|up regulation of immune response													biological_process											owl:Class	
GO:0050776	biolink:NamedThing	regulation of immune response	Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0034667	biolink:NamedThing	integrin alpha3-beta1 complex	An integrin complex that comprises one alpha3 subunit and one beta1 subunit.	got7fsn_ti	VLA-3 complex|alpha3-beta1 integrin complex|ITGA3-ITGB1 complex													cellular_component											owl:Class	
GO:0007602	biolink:NamedThing	phototransduction	The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.	got7fsn_ti	phototrophin mediated phototransduction|opsin|phototransduction, visible light, light adaptation											Wikipedia:Visual_phototransduction		biological_process											owl:Class	
GO:0007165	biolink:NamedThing	signal transduction	The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.	got7fsn_ti	signal transduction by cis-phosphorylation|signalling pathway|signalling cascade|signal transduction by protein phosphorylation|signaling cascade|signal transduction by trans-phosphorylation|signal transduction by conformational transition|signaling pathway				Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.						GO:0023015|GO:0023045|GO:0023014|GO:0023033|GO:0023016	Wikipedia:Signal_transduction		biological_process											owl:Class	
GO:0061709	biolink:NamedThing	reticulophagy	The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.	got7fsn_ti	autophagy of the endoplasmic reticulum|endoplasmic reticulum degradation|ER-phagy|ER degradation|autophagy of the ER|endoplasmic reticulum autophagy|ER autophagy						dph	2015-06-18T15:15:48Z			GO:1990766			biological_process											owl:Class	
GO:1903008	biolink:NamedThing	organelle disassembly	The disaggregation of an organelle into its constituent components.	got7fsn_ti	organelle degradation						jl	2014-05-13T12:36:03Z						biological_process											owl:Class	
GO:0032985	biolink:NamedThing	protein-carbohydrate complex disassembly	The disaggregation of a protein-carbohydrate complex into its constituent components.	got7fsn_ti														biological_process											owl:Class	
GO:0071823	biolink:NamedThing	protein-carbohydrate complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex.	got7fsn_ti	protein-carbohydrate complex subunit organisation						mah	2010-09-08T10:03:03Z						biological_process											owl:Class	
GO:0043326	biolink:NamedThing	chemotaxis to folate	The directed movement of a motile cell or organism in response to the presence of folate.	got7fsn_ti														biological_process											owl:Class	
GO:0006935	biolink:NamedThing	chemotaxis	The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti	taxis in response to chemical stimulus											Wikipedia:Chemotaxis		biological_process											owl:Class	
GO:0000269	biolink:NamedThing	toxin export channel activity	Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	got7fsn_ti														molecular_function											owl:Class	
GO:0075239	biolink:NamedThing	zoospore formation	The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.	got7fsn_ti														biological_process											owl:Class	
GO:0033012	biolink:NamedThing	porosome	A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles.	got7fsn_ti												Wikipedia:Porosome		cellular_component											owl:Class	
GO:0008986	biolink:NamedThing	pyruvate, water dikinase activity	Catalysis of the reaction: ATP + H(2)O + pyruvate = AMP + 3 H(+) + phosphate + phosphoenolpyruvate.	got7fsn_ti	phosphopyruvate synthetase activity|pyruvate-water dikinase (phosphorylating)|pyruvate,water dikinase activity|water pyruvate dikinase activity|ATP:pyruvate, water phosphotransferase activity|phoephoenolpyruvate synthetase activity|PEP synthase activity|phosphoenolpyruvic synthase activity|phosphoenolpyruvate synthase activity|PEP synthetase activity											MetaCyc:PEPSYNTH-RXN|RHEA:11364|EC:2.7.9.2|KEGG_REACTION:R00199		molecular_function											owl:Class	
GO:0016301	biolink:NamedThing	kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	got7fsn_ti	phosphokinase activity				Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term.							Reactome:R-HSA-6788855|Reactome:R-HSA-6788867		molecular_function											owl:Class	
GO:0003875	biolink:NamedThing	ADP-ribosylarginine hydrolase activity	Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose.	got7fsn_ti	ADPribosylarginine hydrolase activity|ADP-ribose-L-arginine cleaving enzyme activity|ADP-ribose-L-arginine cleavage enzyme activity|protein-nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|omega-protein-N-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|protein ADP-ribosylarginine hydrolase activity|N(omega)-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity											RHEA:20784|EC:3.2.2.19|MetaCyc:ADP-RIBOSYLARGININE-HYDROLASE-RXN		molecular_function											owl:Class	
GO:0061756	biolink:NamedThing	leukocyte adhesion to vascular endothelial cell	The attachment of a leukocyte to vascular endothelial cell via adhesion molecules.	got7fsn_ti							dph	2016-02-29T16:42:11Z						biological_process											owl:Class	
GO:0007159	biolink:NamedThing	leukocyte cell-cell adhesion	The attachment of a leukocyte to another cell via adhesion molecules.	got7fsn_ti	leukocyte cell adhesion|leukocyte adhesion													biological_process											owl:Class	
GO:0004877	biolink:NamedThing	complement component C3b receptor activity	Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0004875	biolink:NamedThing	complement receptor activity	Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	anaphylatoxin receptor activity				Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways.						GO:0004942			molecular_function											owl:Class	
GO:0048006	biolink:NamedThing	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.	got7fsn_ti	antigen presentation, endogenous lipid antigen|endogenous lipid antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0048003	biolink:NamedThing	antigen processing and presentation of lipid antigen via MHC class Ib	The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.	got7fsn_ti	lipid antigen processing and presentation via MHC class Ib|antigen presentation, lipid antigen													biological_process											owl:Class	
GO:0048614	biolink:NamedThing	post-embryonic ectodermal digestive tract morphogenesis	The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized.	got7fsn_ti	post-embryonic ectodermal gut morphogenesis													biological_process											owl:Class	
GO:0045496	biolink:NamedThing	male analia development	The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0007487	biolink:NamedThing	analia development	The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0043114	biolink:NamedThing	regulation of vascular permeability	Any process that modulates the extent to which blood vessels can be pervaded by fluid.	got7fsn_ti														biological_process											owl:Class	
GO:0003018	biolink:NamedThing	vascular process in circulatory system	A circulatory process that occurs at the level of the vasculature.	got7fsn_ti	vasculature process													biological_process											owl:Class	
GO:0070978	biolink:NamedThing	voltage-gated calcium channel complex assembly	Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.	got7fsn_ti							mah	2009-10-06T04:51:13Z						biological_process											owl:Class	
GO:0034622	biolink:NamedThing	cellular protein-containing complex assembly	The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.	got7fsn_ti	cellular macromolecule complex assembly|cellular protein complex assembly										GO:0043623			biological_process											owl:Class	
GO:0034558	biolink:NamedThing	technetium (VII) reductase activity	Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-.	got7fsn_ti												UM-BBD_reactionID:r0859		molecular_function											owl:Class	
GO:0016695	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor.	got7fsn_ti	oxidoreductase activity, acting on hydrogen as donor, other acceptors											EC:1.12.-.-		molecular_function											owl:Class	
GO:0051844	biolink:NamedThing	translocation of peptides or proteins into symbiont	The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	transport of peptides or proteins into symbiont													biological_process											owl:Class	
GO:0051862	biolink:NamedThing	translocation of molecules into symbiont	The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	transport of molecules into symbiont													biological_process											owl:Class	
GO:0099004	biolink:NamedThing	calmodulin dependent kinase signaling pathway	Any signal transduction pathway involving calmodulin dependent kinase activity.	got7fsn_ti	CAMK signaling pathway													biological_process											owl:Class	
GO:0102817	biolink:NamedThing	caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) 3'-O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + caffeoyl-CoA <=> gentiodelphin + coenzyme A.	got7fsn_ti												MetaCyc:RXN-8235		molecular_function											owl:Class	
GO:0051747	biolink:NamedThing	cytosine C-5 DNA demethylase activity	Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.	got7fsn_ti	DNA methyltransferase activity acting on cytosine C-5|DNA demethylase activity|hydrolytic DNA demethylase activity													molecular_function											owl:Class	
GO:0140097	biolink:NamedThing	catalytic activity, acting on DNA	Catalytic activity that acts to modify DNA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14225					pg	2017-09-14T12:03:51Z						molecular_function											owl:Class	
GO:0009589	biolink:NamedThing	detection of UV	The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.	got7fsn_ti	perception of UV|detection of ultraviolet light stimulus|detection of ultraviolet radiation stimulus|detection of UV radiation stimulus|detection of UV light stimulus													biological_process											owl:Class	
GO:0009411	biolink:NamedThing	response to UV	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.	got7fsn_ti	response to ultraviolet light stimulus|response to UV radiation stimulus|response to ultraviolet radiation stimulus|response to UV light stimulus													biological_process											owl:Class	
GO:1990385	biolink:NamedThing	meiotic spindle midzone	The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap.	got7fsn_ti							kmv	2014-05-29T20:52:44Z						cellular_component											owl:Class	
GO:0051233	biolink:NamedThing	spindle midzone	The area in the center of the spindle where the spindle microtubules from opposite poles overlap.	got7fsn_ti	spindle equator|central spindle													cellular_component											owl:Class	
GO:0061627	biolink:NamedThing	S-methylmethionine-homocysteine S-methyltransferase activity	Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.	got7fsn_ti	homocysteine transmethylase activity|methylmethionine:homocysteine methyltransferase activity|S-methylmethionine homocysteine transmethylase activity|homocysteine methyltransferase activity						dph	2014-05-14T14:32:02Z				Reactome:R-HSA-5696838|RHEA:26337		molecular_function											owl:Class	
GO:0031463	biolink:NamedThing	Cul3-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.	got7fsn_ti	CDL3 complex|BCR3 complex|cullin-RING ligase 3|BC3B complex|CRL3 complex|SCF3 complex													cellular_component											owl:Class	
GO:0031461	biolink:NamedThing	cullin-RING ubiquitin ligase complex	Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.	got7fsn_ti	CRL complex|cullin complex|cullin-RING ligase													cellular_component											owl:Class	
GO:0072376	biolink:NamedThing	protein activation cascade	A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.	got7fsn_ti	protein activitory cascade|protein activation pathway						mah	2010-11-22T02:54:18Z						biological_process											owl:Class	
GO:0019538	biolink:NamedThing	protein metabolic process	The chemical reactions and pathways involving a protein. Includes protein modification.	got7fsn_ti	protein metabolic process and modification|protein metabolism|protein metabolism and modification|multicellular organismal protein metabolic process										GO:0006411|GO:0044268	Wikipedia:Protein_metabolism		biological_process											owl:Class	
GO:0075137	biolink:NamedThing	response to host redox environment	Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response of symbiont to host redox environment				Note that this term is used to annotate gene products of the symbiont.									biological_process											owl:Class	
GO:0075136	biolink:NamedThing	response to host	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response of symbiont to host				Note that this term is used to annotate gene products of the symbiont.									biological_process											owl:Class	
GO:0102040	biolink:NamedThing	fumarate reductase (menaquinone)	Catalysis of the reaction: fumarate + a menaquinol = succinate + a menaquinone.	got7fsn_ti												EC:1.3.5.4|MetaCyc:R601-RXN|RHEA:27834		molecular_function											owl:Class	
GO:0016635	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound.	got7fsn_ti												EC:1.3.5.-		molecular_function											owl:Class	
GO:0080041	biolink:NamedThing	ADP-ribose pyrophosphohydrolase activity	Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0019144	biolink:NamedThing	ADP-sugar diphosphatase activity	Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate.	got7fsn_ti	ADP-sugar pyrophosphatase activity|ADP-sugar sugarphosphohydrolase activity|nucleoside diphosphate-sugar hydrolase activity|adenosine diphosphosugar pyrophosphatase activity|ADPsugar pyrophosphatase activity											EC:3.6.1.21|MetaCyc:ADPSUGPPHOSPHAT-RXN		molecular_function											owl:Class	
GO:1990334	biolink:NamedThing	Bfa1-Bub2 complex	A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation.	got7fsn_ti							bhm	2014-03-17T14:34:21Z						cellular_component											owl:Class	
GO:1902773	biolink:NamedThing	GTPase activator complex	A protein complex which is capable of GTPase activator activity.	got7fsn_ti					An example of this is BFA1 in Saccharomyces cerevisiae (P47113) in PMID:16449187 (inferred from direct assay).		bhm	2014-03-17T14:26:08Z						cellular_component											owl:Class	
GO:0035233	biolink:NamedThing	germ cell repulsion	The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0060326	biolink:NamedThing	cell chemotaxis	The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti														biological_process											owl:Class	
GO:0007588	biolink:NamedThing	excretion	The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.	got7fsn_ti												Wikipedia:Excretion		biological_process											owl:Class	
GO:0003008	biolink:NamedThing	system process	A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.	got7fsn_ti	organ system process													biological_process											owl:Class	
GO:0004465	biolink:NamedThing	lipoprotein lipase activity	Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein.	got7fsn_ti	postheparin esterase activity|clearing factor lipase activity|postheparin lipase activity|lipemia-clearing factor|diacylglycerol lipase activity|diglyceride lipase activity|triacylglycero-protein acylhydrolase activity|diacylglycerol hydrolase activity											EC:3.1.1.34|Reactome:R-HSA-174757|Reactome:R-HSA-8979996|Reactome:R-HSA-1482811|Reactome:R-HSA-6789310|Reactome:R-HSA-2395768|MetaCyc:LIPOPROTEIN-LIPASE-RXN|Reactome:R-HSA-8980228		molecular_function											owl:Class	
GO:0004806	biolink:NamedThing	triglyceride lipase activity	Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.	got7fsn_ti	triglyceridase activity|glycerol ester hydrolase activity|amano B|triacylglycerol ester hydrolase activity|tween-hydrolyzing esterase activity|tweenesterase activity|amno N-AP|triacylglycerol acylhydrolase activity|tweenase activity|salt-resistant post-heparin lipase|triolein hydrolase activity|triglyceride hydrolase activity|hepatic monoacylglycerol acyltransferase|amano P|triacylglycerol lipase activity|amano CE|meito MY 30|GA 56|butyrinase activity|GEH|takedo 1969-4-9|tributyrinase activity|amano AP|meito sangyo OF lipase|capalase L|glycerol-ester hydrolase activity|amano CES|tributyrin esterase activity|tributyrase activity|liver lipase|TAG activity|post-heparin plasma protamine-resistant lipase|steapsin|tween hydrolase activity|PPL|lipazin|hepatic lipase|cacordase activity|triacetinase activity|heparin releasable hepatic lipase											Reactome:R-HSA-8848339|Reactome:R-HSA-1482777|Reactome:R-HSA-8848338|Reactome:R-HSA-163551|RHEA:12044|EC:3.1.1.3|MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN|Reactome:R-HSA-5694109		molecular_function											owl:Class	
GO:0060086	biolink:NamedThing	circadian temperature homeostasis	Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.	got7fsn_ti	circadian thermoregulation|circadian regulation of body temperature													biological_process											owl:Class	
GO:0001659	biolink:NamedThing	temperature homeostasis	A homeostatic process in which an organism modulates its internal body temperature.	got7fsn_ti	thermoregulation											Wikipedia:Thermoregulation		biological_process											owl:Class	
GO:0120230	biolink:NamedThing	recombinase activator activity	Binds to and increases the activity of a recombinase.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19631|https://github.com/geneontology/go-ontology/issues/19555					krc	2020-06-18T15:54:26Z						molecular_function											owl:Class	
GO:0008047	biolink:NamedThing	enzyme activator activity	Binds to and increases the activity of an enzyme.	got7fsn_ti	metalloenzyme activator activity				This term should only be used in cases when the regulator directly interacts with the enzyme.						GO:0010577			molecular_function											owl:Class	
GO:0021856	biolink:NamedThing	hypothalamic tangential migration using cell-axon interactions	The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0021855	biolink:NamedThing	hypothalamus cell migration	The directed movement of a cell into the hypothalamus region of the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0010850	biolink:NamedThing	regulation of blood pressure by chemoreceptor signaling pathway	A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.	got7fsn_ti	regulation of blood pressure by chemoreceptor signalling pathway													biological_process											owl:Class	
GO:0008217	biolink:NamedThing	regulation of blood pressure	Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.	got7fsn_ti	control of blood pressure|blood pressure regulation|blood pressure homeostasis											Wikipedia:Blood_pressure#Regulation		biological_process											owl:Class	
GO:0031322	biolink:NamedThing	ascospore-type prospore-specific spindle pole body remodeling	A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP).	got7fsn_ti	forespore specific spindle pole body remodeling|ascospore-type prospore-specific spindle pole body remodelling|prospore-specific spindle pole body remodeling|forespore-specific spindle pole body remodeling|sporulation-specific spindle pole body remodeling|ascospore-type prospore-specific spindle pole body modification													biological_process											owl:Class	
GO:0106358	biolink:NamedThing	glycerol-1-phosphate dehydrogenase [NADP+] activity	Catalysis of the reaction: NADP+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADPH.	got7fsn_ti							hjd	2021-02-02T06:08:14Z				RHEA:21416		molecular_function											owl:Class	
GO:0050492	biolink:NamedThing	glycerol-1-phosphate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate.	got7fsn_ti	sn-glycerol-1-phosphate:NAD(P)+ 2-oxidoreductase activity											EC:1.1.1.261|MetaCyc:1.1.1.261-RXN		molecular_function											owl:Class	
GO:0033825	biolink:NamedThing	oligosaccharide 4-alpha-D-glucosyltransferase activity	Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides.	got7fsn_ti	amylase III activity|1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|1,4-alpha-glucan:1,4-alpha-glucan 4-alpha-glucosyltransferase activity											EC:2.4.1.161|MetaCyc:2.4.1.161-RXN		molecular_function											owl:Class	
GO:0046664	biolink:NamedThing	dorsal closure, amnioserosa morphology change	The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0048729	biolink:NamedThing	tissue morphogenesis	The process in which the anatomical structures of a tissue are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:1903431	biolink:NamedThing	positive regulation of cell maturation	Any process that activates or increases the frequency, rate or extent of cell maturation.	got7fsn_ti	up regulation of functional differentiation|positive regulation of functional differentiation|upregulation of functional differentiation|upregulation of cell maturation|activation of functional differentiation|activation of cell maturation|up-regulation of cell maturation|up regulation of cell maturation|up-regulation of functional differentiation						jl	2014-09-15T13:31:41Z						biological_process											owl:Class	
GO:0010720	biolink:NamedThing	positive regulation of cell development	Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:1990484	biolink:NamedThing	aerobic lactate catabolic process	The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen.	got7fsn_ti	aerobic lactic acid catabolic process						tt	2014-09-20T05:42:51Z						biological_process											owl:Class	
GO:1903457	biolink:NamedThing	lactate catabolic process	The chemical reactions and pathways resulting in the breakdown of lactate.	got7fsn_ti	lactate catabolism|lactate degradation|lactate breakdown						pr	2014-09-23T08:41:03Z						biological_process											owl:Class	
GO:0044562	biolink:NamedThing	envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism.	got7fsn_ti							jl	2012-04-05T04:01:49Z						biological_process											owl:Class	
GO:0044559	biolink:NamedThing	envenomation resulting in modulation of voltage-gated potassium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism.	got7fsn_ti							jl	2012-04-05T03:35:20Z						biological_process											owl:Class	
GO:0009720	biolink:NamedThing	detection of hormone stimulus	The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of hormone stimulus													biological_process											owl:Class	
GO:0009725	biolink:NamedThing	response to hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.	got7fsn_ti	response to hormone stimulus|growth regulator													biological_process											owl:Class	
GO:0070529	biolink:NamedThing	L-tryptophan aminotransferase activity	Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0051015	biolink:NamedThing	actin filament binding	Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.	got7fsn_ti	F-actin binding|actin cross-linking activity													molecular_function											owl:Class	
GO:0003779	biolink:NamedThing	actin binding	Binding to monomeric or multimeric forms of actin, including actin filaments.	got7fsn_ti	membrane associated actin binding													molecular_function											owl:Class	
GO:0042795	biolink:NamedThing	snRNA transcription by RNA polymerase II	The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.	got7fsn_ti	snRNA transcription from RNA polymerase II promoter|snRNA transcription from Pol II promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0006366	biolink:NamedThing	transcription by RNA polymerase II	The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).	got7fsn_ti	specific transcription from RNA polymerase II promoter|transcription from Pol II promoter|transcription from RNA polymerase II promoter|gene-specific transcription from RNA polymerase II promoter|general transcription from RNA polymerase II promoter|RNA polymerase II transcription factor activity	https://github.com/geneontology/go-ontology/issues/14854									GO:0032568|GO:0032569			biological_process											owl:Class	
GO:0050878	biolink:NamedThing	regulation of body fluid levels	Any process that modulates the levels of body fluids.	got7fsn_ti														biological_process											owl:Class	
GO:0001791	biolink:NamedThing	IgM binding	Binding to an immunoglobulin of the IgM isotype.	got7fsn_ti														molecular_function											owl:Class	
GO:0019865	biolink:NamedThing	immunoglobulin binding	Binding to an immunoglobulin.	got7fsn_ti														molecular_function											owl:Class	
GO:0075526	biolink:NamedThing	cap snatching	A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.	got7fsn_ti	cap snatching involved in viral mRNA transcription						jl	2011-08-04T01:19:00Z				VZ:839		biological_process											owl:Class	
GO:0075221	biolink:NamedThing	negative regulation of zoospore encystment on host	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0075219	biolink:NamedThing	modulation of zoospore encystment on host	Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0016416	biolink:NamedThing	O-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti												Reactome:R-HSA-2466710|Reactome:R-HSA-2453855|Reactome:R-HSA-2404137		molecular_function											owl:Class	
GO:0008374	biolink:NamedThing	O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti												Reactome:R-HSA-1482867|Reactome:R-HSA-1482850|Reactome:R-HSA-5483229|Reactome:R-HSA-1482781|Reactome:R-HSA-1482775|Reactome:R-HSA-162683|Reactome:R-HSA-422017|Reactome:R-HSA-5358343|Reactome:R-HSA-3238694|Reactome:R-HSA-422104|Reactome:R-HSA-1482861		molecular_function											owl:Class	
GO:0140084	biolink:NamedThing	sexual macrocyst formation	The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum.	got7fsn_ti	macrocyst formation|sexual fusion						pg	2017-08-14T20:11:03Z						biological_process											owl:Class	
GO:0019953	biolink:NamedThing	sexual reproduction	A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.	got7fsn_ti					Sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.							Wikipedia:Sexual_reproduction		biological_process											owl:Class	
GO:0021890	biolink:NamedThing	olfactory bulb interneuron fate commitment	The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb.	got7fsn_ti														biological_process											owl:Class	
GO:0048663	biolink:NamedThing	neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.	got7fsn_ti	neuronal lineage restriction|neuron lineage restriction										GO:0042055			biological_process											owl:Class	
GO:0005622	biolink:NamedThing	intracellular anatomical structure	A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.	got7fsn_ti	intracellular|internal to cell|nucleocytoplasm|protoplasm|protoplast	https://github.com/geneontology/go-ontology/issues/17776										Wikipedia:Intracellular		cellular_component											owl:Class	
GO:0003262	biolink:NamedThing	endocardial progenitor cell migration to the midline involved in heart field formation	The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart.	got7fsn_ti							dph	2009-10-15T02:00:41Z						biological_process											owl:Class	
GO:0060975	biolink:NamedThing	cardioblast migration to the midline involved in heart field formation	The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	cardioblast midline convergence|cardiac progenitor cell midline migration						dph	2009-10-06T10:59:36Z						biological_process											owl:Class	
GO:0010316	biolink:NamedThing	pyrophosphate-dependent phosphofructokinase complex	Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate.	got7fsn_ti	PFK complex													cellular_component											owl:Class	
GO:0061660	biolink:NamedThing	Atg12 ligase activity	Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3						dph	2014-11-06T13:50:42Z						molecular_function											owl:Class	
GO:0061659	biolink:NamedThing	ubiquitin-like protein ligase activity	Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3|small conjugating protein ligase activity						dph	2014-11-06T13:46:23Z						molecular_function											owl:Class	
GO:0106370	biolink:NamedThing	protein-L-histidine N-pros-methyltransferase activity	Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.	got7fsn_ti							hjd	2021-03-22T15:13:06Z				RHEA:67076		molecular_function											owl:Class	
GO:0008757	biolink:NamedThing	S-adenosylmethionine-dependent methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.	got7fsn_ti	SAM-dependent methyltransferase activity|S-adenosyl methionine-dependent methyltransferase activity													molecular_function											owl:Class	
GO:0071356	biolink:NamedThing	cellular response to tumor necrosis factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.	got7fsn_ti	cellular response to TNF						mah	2009-12-11T02:51:37Z						biological_process											owl:Class	
GO:0034612	biolink:NamedThing	response to tumor necrosis factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.	got7fsn_ti	response to TNF													biological_process											owl:Class	
GO:0043488	biolink:NamedThing	regulation of mRNA stability	Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.	got7fsn_ti														biological_process											owl:Class	
GO:0043487	biolink:NamedThing	regulation of RNA stability	Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs.	got7fsn_ti														biological_process											owl:Class	
GO:0048343	biolink:NamedThing	paraxial mesodermal cell fate commitment	The process in which a cell becomes committed to become a paraxial mesoderm cell.	got7fsn_ti														biological_process											owl:Class	
GO:0001710	biolink:NamedThing	mesodermal cell fate commitment	The cell differentiation process that results in commitment of a cell to become part of the mesoderm.	got7fsn_ti	mesoderm cell fate commitment													biological_process											owl:Class	
GO:0120174	biolink:NamedThing	stress-induced homeostatically regulated protein degradation pathway	A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway.	got7fsn_ti	SHRED pathway				Note, although the SHRED pathway may contain some components in common with ER-associated protein degradation (ERAD) pathways (GO:0036503), such as UBR1, RAD6 and CDC48, other ERAD components, such as HRD1 and DOA10 do not appear to be involved, and as such these pathways are currently considered to be distinct. ERAD pathways target misfolded ER lumenal proteins (ERAD-L), ER membrane proteins (ERAD-M) and ER proteins with misfolded cytosolic domains (ERAD-C) by recognizing aberrant proteins, retrotranslocating these substrates to the cytosol, followed by subsequent substrate ubiquitination and proteosome-mediated degradation. In contrast the SHRED pathway, although inducible by stress, targets diverse ER membrane and cytosolic proteins as well as numerous other native proteins in the absence of stress. In the SHRED pathway an Nma111p serine protease-mediated cleavage results in the generation of a Roq1p fragment that then binds to the type-1 active site of Ubr1p, altering its substrate specificity, and leading to the proteasome-mediated degradation of both misfolded and native proteins. SHRED is also considered to be distinct from the endoplasmic reticulum unfolded protein response (GO:0030968), a process by which ER stress activates the ER membrane protein Ire1p, resulting in splicing of the HAC1 mRNA, followed by Hac1p-mediated up-regulation of UPR genes. Induction of SHRED does not require IRE1 or HAC1, and as such is currently considered to be distinct.		krc	2018-06-07T16:16:43Z						biological_process											owl:Class	
GO:0033554	biolink:NamedThing	cellular response to stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0005252	biolink:NamedThing	open rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration.	got7fsn_ti														molecular_function											owl:Class	
GO:0005249	biolink:NamedThing	voltage-gated potassium channel activity	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-sensitive potassium channel|voltage-dependent potassium channel activity|voltage gated potassium channel activity|voltage-gated potassium ion channel activity											Reactome:R-HSA-1296127		molecular_function											owl:Class	
GO:0051877	biolink:NamedThing	pigment granule aggregation in cell center	The directed movement of dispersed pigment granules towards the center of the cell.	got7fsn_ti														biological_process											owl:Class	
GO:0051905	biolink:NamedThing	establishment of pigment granule localization	The directed movement of a pigment granule to a specific location.	got7fsn_ti	establishment of pigment granule localisation													biological_process											owl:Class	
GO:0102275	biolink:NamedThing	cysteine-S-conjugate N-malonyl transferase activity	Catalysis of the reaction: malonyl-CoA(5-) + an L-cysteine-S-conjugate <=> coenzyme A + H+ + an N-malonyl-L-cysteine-S-conjugate.	got7fsn_ti												MetaCyc:RXN-12534		molecular_function											owl:Class	
GO:0003401	biolink:NamedThing	axis elongation	The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure.	got7fsn_ti	elongation of an axis						dph	2009-12-21T01:12:15Z						biological_process											owl:Class	
GO:0047485	biolink:NamedThing	protein N-terminus binding	Binding to a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.	got7fsn_ti	amino-terminus binding|NH2-terminus binding|N-terminal binding|NH2-terminal binding|N-terminal end binding|amino-terminal binding													molecular_function											owl:Class	
GO:0005515	biolink:NamedThing	protein binding	Binding to a protein.	got7fsn_ti	protein amino acid binding|glycoprotein binding										GO:0045308|GO:0001948			molecular_function											owl:Class	
GO:0140582	biolink:NamedThing	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway	A series of molecular signals initiated by cAMP binding to its receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex.	got7fsn_ti	extracellular cAMP signaling pathway	https://github.com/geneontology/go-ontology/issues/20487					pg	2021-01-18T19:30:30Z						biological_process											owl:Class	
GO:0007189	biolink:NamedThing	adenylate cyclase-activating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP).	got7fsn_ti	positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|positive regulation of adenylate cyclase activity by G-protein signalling pathway|G-protein signalling, adenylate cyclase activating pathway|G-protein signaling, adenylate cyclase activating pathway|G protein signalling, adenylate cyclase activating pathway|G protein signaling, adenylate cyclase activating pathway|GPCR signaling pathway via activation of adenylate cyclase|G-protein signaling, adenylyl cyclase activating pathway|G protein signalling, adenylyl cyclase activating pathway|G protein signaling, adenylyl cyclase activating pathway|activation of adenylate cyclase activity by G-protein signaling pathway|GPCR signaling pathway via activation of adenylate cyclase activity|adenylate cyclase-activating GPCR signaling pathway|activation of adenylate cyclase activity involved in G-protein signaling|positive regulation of adenylate cyclase activity by G-protein signaling pathway|G-protein signalling, adenylyl cyclase activating pathway				This term can be used to annotate ligands, receptors and G-proteins that lead to activation of adenylate cyclase activity within a signaling pathway.						GO:0010579|GO:0010580			biological_process											owl:Class	
GO:0071595	biolink:NamedThing	Nem1-Spo7 phosphatase complex	A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.	got7fsn_ti							mah	2010-01-29T02:17:29Z						cellular_component											owl:Class	
GO:0033802	biolink:NamedThing	isoliquiritigenin 2'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase activity|chalcone OMT|CHMT											KEGG_REACTION:R07242|RHEA:21608|MetaCyc:RXN-3501|EC:2.1.1.154		molecular_function											owl:Class	
GO:0061201	biolink:NamedThing	clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen	The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.	got7fsn_ti	clathrin sculpted gamma-aminobutyric acid transport vesicle lumen|clathrin sculpted GABA transport vesicle lumen						dph	2010-07-29T10:45:05Z						cellular_component											owl:Class	
GO:0060205	biolink:NamedThing	cytoplasmic vesicle lumen	The volume enclosed by a cytoplasmic vesicle.	got7fsn_ti	cytoplasmic membrane-enclosed vesicle lumen|cytoplasmic membrane-bounded vesicle lumen													cellular_component											owl:Class	
GO:0048256	biolink:NamedThing	flap endonuclease activity	Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.	got7fsn_ti														molecular_function											owl:Class	
GO:0004520	biolink:NamedThing	endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	got7fsn_ti	endonuclease G activity|DNA nicking activity											Reactome:R-HSA-5690988|Reactome:R-HSA-6782224|Reactome:R-HSA-5693608|Reactome:R-HSA-5687464|Reactome:R-HSA-110359|Reactome:R-HSA-5686657|Reactome:R-HSA-6782204|Reactome:R-HSA-5693584|Reactome:R-HSA-5686440|Reactome:R-HSA-9023941		molecular_function											owl:Class	
GO:0031261	biolink:NamedThing	DNA replication preinitiation complex	A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.	got7fsn_ti	pre-IC													cellular_component											owl:Class	
GO:0032993	biolink:NamedThing	protein-DNA complex	A macromolecular complex containing both protein and DNA molecules.	got7fsn_ti	DNA-protein complex				Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here.									cellular_component											owl:Class	
GO:0044736	biolink:NamedThing	acid-sensing ion channel activity	Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.	got7fsn_ti	ASIC activity						jl	2012-11-06T16:36:37Z				Reactome:R-HSA-2671885|Wikipedia:Acid-sensing_ion_channel		molecular_function											owl:Class	
GO:0015280	biolink:NamedThing	ligand-gated sodium channel activity	Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	ASIC activity|epithelial sodium channel|amiloride-sensitive sodium channel activity|acid-sensing ion channel activity											Reactome:R-HSA-2672334		molecular_function											owl:Class	
GO:0003423	biolink:NamedThing	growth plate cartilage chondrocyte division	The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate.	got7fsn_ti							dph	2009-12-22T09:55:51Z						biological_process											owl:Class	
GO:0051301	biolink:NamedThing	cell division	The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.	got7fsn_ti					Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division.							Wikipedia:Cell_division		biological_process											owl:Class	
GO:0042073	biolink:NamedThing	intraciliary transport	The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.	got7fsn_ti	intraflagellar transport involved in cilium organization|IFT|intraflagellar transport involved in microtubule-based flagellum organisation|intraflagellar transport				Note that we deem cilium and microtubule-based flagellum to be equivalent.						GO:0035734	Wikipedia:Intraflagellar_transport		biological_process											owl:Class	
GO:0010970	biolink:NamedThing	transport along microtubule	The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.	got7fsn_ti	movement along microtubule|establishment of localization by movement along microtubule|microtubule-based transport						tb	2009-05-27T10:56:08Z						biological_process											owl:Class	
GO:0061388	biolink:NamedThing	regulation of rate of cell growth	Any process that modulates the rate of cell growth.	got7fsn_ti							dph	2011-07-14T10:18:06Z						biological_process											owl:Class	
GO:0001558	biolink:NamedThing	regulation of cell growth	Any process that modulates the frequency, rate, extent or direction of cell growth.	got7fsn_ti														biological_process											owl:Class	
GO:0072663	biolink:NamedThing	establishment of protein localization to peroxisome	The directed movement of a protein to a specific location in a peroxisome.	got7fsn_ti	establishment of protein localisation to peroxisome						mah	2011-02-14T02:50:36Z						biological_process											owl:Class	
GO:0072594	biolink:NamedThing	establishment of protein localization to organelle	The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.	got7fsn_ti	establishment of protein localisation to organelle						mah	2011-02-14T01:56:51Z						biological_process											owl:Class	
GO:0031578	biolink:NamedThing	mitotic spindle orientation checkpoint signaling	A signaling process that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.	got7fsn_ti	SPOC|signal transduction involved in mitotic cell cycle spindle orientation checkpoint|SOC|mitotic cell cycle spindle orientation checkpoint|spindle position checkpoint|mitotic spindle orientation checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072483			biological_process											owl:Class	
GO:0001100	biolink:NamedThing	negative regulation of exit from mitosis	Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).	got7fsn_ti	downregulation of exit from mitosis|down regulation of exit from mitosis|inhibition of exit from mitosis|down-regulation of exit from mitosis													biological_process											owl:Class	
GO:0106335	biolink:NamedThing	tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity	Catalysis of the reaction: carboxymethyluridine34 in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine.	got7fsn_ti							hjd	2020-10-27T21:34:30Z				RHEA:43208|EC:2.1.1.229		molecular_function											owl:Class	
GO:0060718	biolink:NamedThing	chorionic trophoblast cell differentiation	The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.	got7fsn_ti							dph	2009-06-11T02:48:27Z						biological_process											owl:Class	
GO:0030381	biolink:NamedThing	chorion-containing eggshell pattern formation	The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects.	got7fsn_ti														biological_process											owl:Class	
GO:0034752	biolink:NamedThing	cytosolic aryl hydrocarbon receptor complex	An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.	got7fsn_ti	cytosolic AhR complex|cytosolic AHRC|9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex													cellular_component											owl:Class	
GO:0034751	biolink:NamedThing	aryl hydrocarbon receptor complex	A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.	got7fsn_ti	AhR complex|AHRC													cellular_component											owl:Class	
GO:0005024	biolink:NamedThing	transforming growth factor beta-activated receptor activity	Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	got7fsn_ti	TGFbeta-activated receptor activity|TGF-beta receptor activity|transforming growth factor beta receptor activity|TGFbeta receptor activity|TGFbetaR				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.									molecular_function											owl:Class	
GO:0004675	biolink:NamedThing	transmembrane receptor protein serine/threonine kinase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	got7fsn_ti	receptor protein serine/threonine kinase activity|receptor serine/threonine protein kinase activity											EC:2.7.11.30|Reactome:R-HSA-198732|Reactome:R-HSA-170868|Reactome:R-HSA-201476|MetaCyc:2.7.11.30-RXN|RHEA:18673		molecular_function											owl:Class	
GO:0047563	biolink:NamedThing	3-hydroxybenzoate 2-monooxygenase activity	Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O(2) = 2,3-dihydroxybenzoate + A + H(2)O.	got7fsn_ti	3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)|3-hydroxybenzoate 2-hydroxylase activity|3-HBA-2-hydroxylase activity											KEGG_REACTION:R01508|RHEA:14193|MetaCyc:3-HYDROXYBENZOATE-2-MONOOXYGENASE-RXN|EC:1.14.99.23		molecular_function											owl:Class	
GO:0031051	biolink:NamedThing	scnRNA processing	Cleavage of noncoding, double-stranded RNAs transcribed from the micronuclear genome to produce scnRNAs, small RNAs (~28 nucleotides) that direct the deletion of micronuclear-limited sequences from the developing macronuclear genome.	got7fsn_ti	scnRNA production													biological_process											owl:Class	
GO:0031050	biolink:NamedThing	dsRNA processing	Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.	got7fsn_ti	dsRNA fragmentation|double-stranded RNA fragmentation													biological_process											owl:Class	
GO:0019133	biolink:NamedThing	choline monooxygenase activity	Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.	got7fsn_ti	choline,reduced-ferredoxin:oxygen oxidoreductase activity											RHEA:17769|EC:1.14.15.7|MetaCyc:RXN1F-357		molecular_function											owl:Class	
GO:0016713	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.	got7fsn_ti	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulphur protein as one donor, and incorporation of one atom of oxygen											EC:1.14.15.-		molecular_function											owl:Class	
GO:0031776	biolink:NamedThing	melanin-concentrating hormone receptor binding	Binding to a melanin-concentrating hormone receptor.	got7fsn_ti	melanin-concentrating hormone receptor ligand													molecular_function											owl:Class	
GO:0071855	biolink:NamedThing	neuropeptide receptor binding	Binding to a neuropeptide receptor.	got7fsn_ti							mah	2010-09-10T03:21:43Z						molecular_function											owl:Class	
GO:0002774	biolink:NamedThing	Fc receptor mediated inhibitory signaling pathway	A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.	got7fsn_ti	Fc-receptor mediated inhibitory signaling pathway|Fc receptor mediated inhibitory signalling pathway													biological_process											owl:Class	
GO:0002767	biolink:NamedThing	immune response-inhibiting cell surface receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response.	got7fsn_ti	immune response-inhibiting cell surface receptor signalling pathway													biological_process											owl:Class	
GO:0032797	biolink:NamedThing	SMN complex	A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus.	got7fsn_ti	survival motor neuron complex|SMN core complex				Note that a larger complex containing Sm proteins and other subunits is also sometimes referred to as the 'SMN complex'. The larger complex is represented by 'SMN-Sm protein complex ; GO:0034719'.									cellular_component											owl:Class	
GO:0120114	biolink:NamedThing	Sm-like protein family complex	A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles.	got7fsn_ti							krc	2017-11-06T18:46:43Z						cellular_component											owl:Class	
GO:0046960	biolink:NamedThing	sensitization	An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched.	got7fsn_ti												Wikipedia:Sensitization		biological_process											owl:Class	
GO:0046958	biolink:NamedThing	nonassociative learning	A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.	got7fsn_ti	unconditional response													biological_process											owl:Class	
GO:0140511	biolink:NamedThing	mitotic nuclear bridge stalk	Either of the regions of a mitotic nuclear bridge proximal to the main portion of each daughter nucleus. The nuclear envelope in the stalk regions is depleted of nuclear pore complexes.	got7fsn_ti							pg	2020-09-07T10:06:23Z						cellular_component											owl:Class	
GO:0016667	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on sulfur group of donors, other acceptors|oxidoreductase activity, acting on sulphur group of donors											EC:1.8.-.-|Reactome:R-HSA-2213240		molecular_function											owl:Class	
GO:0097531	biolink:NamedThing	mast cell migration	The movement of a mast cell within or between different tissues and organs of the body.	got7fsn_ti							pr	2013-11-11T14:01:41Z						biological_process											owl:Class	
GO:0097529	biolink:NamedThing	myeloid leukocyte migration	The movement of a myeloid leukocyte within or between different tissues and organs of the body.	got7fsn_ti							pr	2013-11-11T13:59:43Z						biological_process											owl:Class	
GO:0047623	biolink:NamedThing	adenosine-phosphate deaminase activity	Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP.	got7fsn_ti	adenosine-phosphate aminohydrolase activity|adenine nucleotide deaminase activity|adenosine (phosphate) deaminase activity				Consider instead annotating to one of the more specific terms: AMP deaminase activity ; GO:0003876, ADP deaminase activity ; GO:0047629, or ATP deaminase activity ; GO:0047692.							MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN|EC:3.5.4.17		molecular_function											owl:Class	
GO:0016814	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.	got7fsn_ti												EC:3.5.4.-		molecular_function											owl:Class	
GO:0047827	biolink:NamedThing	D-lysopine dehydrogenase activity	Catalysis of the reaction: D-lysopine + H(2)O + NADP(+) = L-lysine + H(+) + NADPH + pyruvate.	got7fsn_ti	2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|lysopine dehydrogenase activity|D(+)-lysopine dehydrogenase activity|D-lysopine synthase activity											RHEA:17625|EC:1.5.1.16|KEGG_REACTION:R00452|MetaCyc:D-LYSOPINE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0016646	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP.	got7fsn_ti												EC:1.5.1.-		molecular_function											owl:Class	
GO:0002144	biolink:NamedThing	cytosolic tRNA wobble base thiouridylase complex	A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets.	got7fsn_ti	tRNA thiouridylase|Cut1-Cut2 complex						hjd	2009-05-08T02:32:55Z						cellular_component											owl:Class	
GO:0030217	biolink:NamedThing	T cell differentiation	The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.	got7fsn_ti	T cell development|T lymphocyte differentiation|T-lymphocyte differentiation|T-cell differentiation				Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.						GO:0042112|GO:0046652			biological_process											owl:Class	
GO:0042110	biolink:NamedThing	T cell activation	The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti	T-cell activation|T-lymphocyte activation|T lymphocyte activation													biological_process											owl:Class	
GO:0072119	biolink:NamedThing	head kidney structural organization	The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.	got7fsn_ti	head kidney structural organisation						mah	2010-02-22T11:22:12Z						biological_process											owl:Class	
GO:0072118	biolink:NamedThing	pronephros structural organization	The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	got7fsn_ti	pronephric kidney structural organization|pronephros structural organisation						mah	2010-02-22T11:21:38Z						biological_process											owl:Class	
GO:0045701	biolink:NamedThing	negative regulation of spermatid nuclear differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.	got7fsn_ti	inhibition of spermatid nuclear differentiation|down-regulation of spermatid nuclear differentiation|down regulation of spermatid nuclear differentiation|downregulation of spermatid nuclear differentiation													biological_process											owl:Class	
GO:0045596	biolink:NamedThing	negative regulation of cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.	got7fsn_ti	down regulation of cell differentiation|downregulation of cell differentiation|down-regulation of cell differentiation|inhibition of cell differentiation													biological_process											owl:Class	
GO:0002209	biolink:NamedThing	behavioral defense response	A behavioral response seeking to protect an organism from an a perceived external threat to that organism.	got7fsn_ti	behavioural defense response													biological_process											owl:Class	
GO:0006952	biolink:NamedThing	defense response	Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.	got7fsn_ti	defense/immunity protein activity|defence response|antimicrobial peptide activity|physiological defense response										GO:0002217|GO:0042829			biological_process											owl:Class	
GO:0022013	biolink:NamedThing	pallium cell proliferation in forebrain	The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0021846	biolink:NamedThing	cell proliferation in forebrain	The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.	got7fsn_ti														biological_process											owl:Class	
GO:0018292	biolink:NamedThing	molybdenum incorporation via L-cysteinyl molybdopterin	The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin.	got7fsn_ti												RESID:AA0142		biological_process											owl:Class	
GO:0018315	biolink:NamedThing	molybdenum incorporation into molybdenum-molybdopterin complex	The incorporation of molybdenum into a molybdenum-molybdopterin complex.	got7fsn_ti	molybdenum incorporation into metallo-pterin complex										GO:0042041			biological_process											owl:Class	
GO:0004750	biolink:NamedThing	ribulose-phosphate 3-epimerase activity	Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate.	got7fsn_ti	erythrose-4-phosphate isomerase activity|ribulose 5-phosphate 3-epimerase activity|pentose-5-phosphate 3-epimerase activity|D-ribulose-5-P 3-epimerase activity|D-xylulose-5-phosphate 3-epimerase activity|xylulose phosphate 3-epimerase activity|D-ribulose-5-phosphate epimerase activity|erythrose-4-phosphate epimerase activity|phosphoketopentose 3-epimerase activity|D-ribulose phosphate-3-epimerase activity|D-ribulose 5-phosphate epimerase activity|phosphoketopentose epimerase activity|D-ribulose-5-phosphate 3-epimerase activity|phosphoribulose epimerase activity											Reactome:R-HSA-71303|Reactome:R-HSA-199803|KEGG_REACTION:R01529|RHEA:13677|MetaCyc:RIBULP3EPIM-RXN|EC:5.1.3.1		molecular_function											owl:Class	
GO:0016857	biolink:NamedThing	racemase and epimerase activity, acting on carbohydrates and derivatives	Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule.	got7fsn_ti												Reactome:R-HSA-6787677|EC:5.1.3.-		molecular_function											owl:Class	
GO:0015024	biolink:NamedThing	glucuronate-2-sulfatase activity	Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.	got7fsn_ti	glucurono-2-sulfatase activity|polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase activity|glucuronate-2-sulphatase activity|chondro-2-sulfatase activity											MetaCyc:3.1.6.18-RXN|EC:3.1.6.18		molecular_function											owl:Class	
GO:0008484	biolink:NamedThing	sulfuric ester hydrolase activity	Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of a sulfuric ester bond, an ester formed from sulfuric acid, O=SO(OH)2.	got7fsn_ti	sulfatase activity|sulphuric ester hydrolase activity											MetaCyc:ARYLSULFAT-RXN|EC:3.1.6.-		molecular_function											owl:Class	
GO:0042447	biolink:NamedThing	hormone catabolic process	The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.	got7fsn_ti	hormone breakdown|hormone catabolism|hormone degradation													biological_process											owl:Class	
GO:0034115	biolink:NamedThing	negative regulation of heterotypic cell-cell adhesion	Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.	got7fsn_ti														biological_process											owl:Class	
GO:0070587	biolink:NamedThing	regulation of cell-cell adhesion involved in gastrulation	Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.	got7fsn_ti							mah	2009-04-24T02:51:07Z						biological_process											owl:Class	
GO:0047995	biolink:NamedThing	hydroxyphenylpyruvate reductase activity	Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH.	got7fsn_ti	HPRP|4-hydroxyphenyllactate:NAD+ oxidoreductase activity											EC:1.1.1.237|RHEA:10780|MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0044649	biolink:NamedThing	envenomation resulting in cytolysis in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with cytolysis in the bitten organism.	got7fsn_ti							jl	2012-07-11T02:13:38Z						biological_process											owl:Class	
GO:0047676	biolink:NamedThing	arachidonate-CoA ligase activity	Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H(+).	got7fsn_ti	arachidonate:CoA ligase (AMP-forming)|arachidonoyl-CoA synthetase activity											RHEA:19713|MetaCyc:ARACHIDONATE--COA-LIGASE-RXN|KEGG_REACTION:R01598|EC:6.2.1.15		molecular_function											owl:Class	
GO:0016405	biolink:NamedThing	CoA-ligase activity	Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.	got7fsn_ti												Reactome:R-HSA-177157|Reactome:R-HSA-159443|Reactome:R-HSA-6798345|Reactome:R-HSA-159567		molecular_function											owl:Class	
GO:0075313	biolink:NamedThing	basidium development	The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.	got7fsn_ti					Note that basidiospores and basidia are separate biological structures. The basidium is the structure that bear the basidiospores, but the development of the basidium is a different process than the formation of the basidiospores themselves. For this reason, GO:0034295 basidiospore formation and GO:0075313 basidium development are different terms and are not linked.									biological_process											owl:Class	
GO:0075259	biolink:NamedThing	spore-bearing structure development	The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores.	got7fsn_ti	sporangium development|sporophore development|fruiting structure development|spore-bearing organ development													biological_process											owl:Class	
GO:0005146	biolink:NamedThing	leukemia inhibitory factor receptor binding	Binding to an leukemia inhibitory factor receptor.	got7fsn_ti	leukemia inhibitory factor|leukemia inhibitory factor receptor ligand													molecular_function											owl:Class	
GO:0005126	biolink:NamedThing	cytokine receptor binding	Binding to a cytokine receptor.	got7fsn_ti	hematopoietin/interferon-class (D200-domain) cytokine receptor binding|hematopoietin/interferon-class (D200-domain) cytokine receptor ligand													molecular_function											owl:Class	
GO:0036313	biolink:NamedThing	phosphatidylinositol 3-kinase catalytic subunit binding	Binding to the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.	got7fsn_ti	p110 binding|PI3K catalytic subunit binding						bf	2012-08-16T10:58:45Z						molecular_function											owl:Class	
GO:0009757	biolink:NamedThing	hexose mediated signaling	A series of molecular signals mediated by the detection of hexose.	got7fsn_ti	hexose mediated signalling													biological_process											owl:Class	
GO:0010182	biolink:NamedThing	sugar mediated signaling pathway	The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.	got7fsn_ti	sugar mediated signalling													biological_process											owl:Class	
GO:0018069	biolink:NamedThing	peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone	The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase.	got7fsn_ti												RESID:AA0149		biological_process											owl:Class	
GO:0018149	biolink:NamedThing	peptide cross-linking	The formation of a covalent cross-link between or within protein chains.	got7fsn_ti														biological_process											owl:Class	
GO:0048653	biolink:NamedThing	anther development	The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0034214	biolink:NamedThing	protein hexamerization	The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.	got7fsn_ti	protein hexamer biosynthesis|protein hexamer assembly|protein hexamer biosynthetic process|protein hexamer formation													biological_process											owl:Class	
GO:0051259	biolink:NamedThing	protein complex oligomerization	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	got7fsn_ti	protein oligomer biosynthesis|protein multimerization|protein oligomer formation|protein oligomer biosynthetic process|protein oligomer assembly|protein oligomerization						bf	2011-04-05T09:57:49Z			GO:0035786			biological_process											owl:Class	
GO:0051220	biolink:NamedThing	cytoplasmic sequestering of protein	The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell.	got7fsn_ti	storage of protein in cytoplasm|maintenance of protein location in cytoplasm|cytoplasmic storage of protein|retention of protein in cytoplasm|sequestration of protein in cytoplasm|cytoplasmic retention of protein|cytoplasmic sequestration of protein|sequestering of protein in cytoplasm													biological_process											owl:Class	
GO:0045185	biolink:NamedThing	maintenance of protein location	Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.	got7fsn_ti	protein retention|protein sequestering|maintenance of protein localization|active protein retrieval													biological_process											owl:Class	
GO:0102553	biolink:NamedThing	lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + a [pyruvate dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine  + 2 5'-deoxyadenosine + 2 H+ + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier].	got7fsn_ti												EC:2.8.1.8|MetaCyc:RXN-14957		molecular_function											owl:Class	
GO:0031323	biolink:NamedThing	regulation of cellular metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.	got7fsn_ti	regulation of cellular metabolism													biological_process											owl:Class	
GO:0009570	biolink:NamedThing	chloroplast stroma	The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0009532	biolink:NamedThing	plastid stroma	The proteinaceous ground substance of plastids.	got7fsn_ti														cellular_component											owl:Class	
GO:0061291	biolink:NamedThing	canonical Wnt signaling pathway involved in ureteric bud branching	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in ureteric bud branching|canonical Wnt receptor signaling pathway involved in ureteric bud branching						dph	2010-09-03T12:15:19Z						biological_process											owl:Class	
GO:0061290	biolink:NamedThing	canonical Wnt signaling pathway involved in metanephric kidney development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in metanephric kidney development|canonical Wnt-activated signaling pathway involved in metanephric kidney development|canonical Wnt receptor signalling pathway involved in metanephric kidney development						dph	2010-09-03T12:06:10Z						biological_process											owl:Class	
GO:0033874	biolink:NamedThing	scymnol sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+).	got7fsn_ti												RHEA:15477|EC:2.8.2.32|KEGG_REACTION:R07798|MetaCyc:2.8.2.32-RXN		molecular_function											owl:Class	
GO:0019105	biolink:NamedThing	N-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0042311	biolink:NamedThing	vasodilation	An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.	got7fsn_ti	positive regulation of blood vessel size|vasodilatation	https://github.com/geneontology/go-ontology/issues/12253									GO:0045909	Wikipedia:Vasodilation		biological_process											owl:Class	
GO:0097746	biolink:NamedThing	blood vessel diameter maintenance	Any process that modulates the diameter of blood vessels.	got7fsn_ti	regulation of vasodilation|blood vessel diameter homeostasis|regulation of blood vessel diameter|regulation of vasodilatation|regulation of blood vessel size	https://github.com/geneontology/go-ontology/issues/12253					pr	2016-11-24T15:45:05Z			GO:0042312|GO:0050880			biological_process											owl:Class	
GO:0008106	biolink:NamedThing	alcohol dehydrogenase (NADP+) activity	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.	got7fsn_ti	NADP-aldehyde reductase activity|alcohol:NADP dehydrogenase activity|aldehyde reductase (NADPH) activity|aldehyde reductase (NADPH2) activity											MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN|RHEA:15937|EC:1.1.1.2		molecular_function											owl:Class	
GO:0004033	biolink:NamedThing	aldo-keto reductase (NADP) activity	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+.	got7fsn_ti	aldo-keto reductase activity|aldo-keto reductase (NADP+) activity|NADPH-dependent aldo-keto reductase activity|alcohol dehydrogenase (NADP+) activity											Reactome:R-HSA-193800|Reactome:R-HSA-5692232|Reactome:R-HSA-193821|Reactome:R-HSA-9027598|Reactome:R-HSA-9027531|Reactome:R-HSA-5423637|Reactome:R-HSA-192067|Reactome:R-HSA-9027600|Reactome:R-HSA-193746|Reactome:R-HSA-192033|Reactome:R-HSA-193781|Reactome:R-HSA-192160|Reactome:R-HSA-193758|Reactome:R-HSA-2855252|Reactome:R-HSA-192036|Reactome:R-HSA-193755|Reactome:R-HSA-193824|Reactome:R-HSA-193841|Reactome:R-HSA-198845|Reactome:R-HSA-9027562		molecular_function											owl:Class	
GO:0038196	biolink:NamedThing	type III interferon signaling pathway	A series of molecular signals initiated by the binding of a type III interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	interferon lambda signaling pathway|type III interferon-activated signaling pathway						bf	2013-11-27T14:25:49Z						biological_process											owl:Class	
GO:0048513	biolink:NamedThing	animal organ development	Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti	development of an organ|organogenesis											Wikipedia:Organogenesis		biological_process											owl:Class	
GO:0097493	biolink:NamedThing	structural molecule activity conferring elasticity	The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling.	got7fsn_ti							pr	2013-07-26T09:47:26Z						molecular_function											owl:Class	
GO:0005198	biolink:NamedThing	structural molecule activity	The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.	got7fsn_ti														molecular_function											owl:Class	
GO:0000804	biolink:NamedThing	W chromosome	The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females.	got7fsn_ti												Wikipedia:ZW_sex-determination_system		cellular_component											owl:Class	
GO:0070456	biolink:NamedThing	galactose-1-phosphate phosphatase activity	Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0050308	biolink:NamedThing	sugar-phosphatase activity	Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.	got7fsn_ti	sugar-phosphate phosphohydrolase activity|sugar-phosphate phosphatase activity											MetaCyc:SUGAR-PHOSPHATASE-RXN|KEGG_REACTION:R00804|EC:3.1.3.23		molecular_function											owl:Class	
GO:0071559	biolink:NamedThing	response to transforming growth factor beta	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.	got7fsn_ti	response to TGF-beta stimulus|response to TGFbeta stimulus|response to transforming growth factor beta stimulus						mah	2010-01-20T11:49:59Z						biological_process											owl:Class	
GO:0005684	biolink:NamedThing	U2-type spliceosomal complex	Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.	got7fsn_ti	GT-AG spliceosome|major spliceosomal complex|major (U2-type) spliceosomal complex				A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP.									cellular_component											owl:Class	
GO:0005681	biolink:NamedThing	spliceosomal complex	Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.	got7fsn_ti	spliceosome complex|spliceosome											Wikipedia:Spliceosome		cellular_component											owl:Class	
GO:0002128	biolink:NamedThing	tRNA nucleoside ribose methylation	The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position.	got7fsn_ti														biological_process											owl:Class	
GO:0030488	biolink:NamedThing	tRNA methylation	The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0004508	biolink:NamedThing	steroid 17-alpha-monooxygenase activity	Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O.	got7fsn_ti	steroid 17alpha-hydroxylase activity|cytochrome P450 CYP17|steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)|steroid 17-alpha-hydroxylase activity|steroid 17alpha-monooxygenase activity|17alpha-hydroxylase-C17,20 lyase activity|steroid 17-alpha-hydroxylase/17,20 lyase activity|cytochrome p450 XVIIA1 activity|cytochrome P45017alpha|steroid 17-alpha-hydroxylase-C17-20 lyase activity|steroid 17alphahydroxylase/17,20 lyase activity|cytochrome P-450 (P-45017alpha,lyase)											Reactome:R-HSA-193072|Reactome:R-HSA-193099|MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN|Reactome:R-HSA-9035954|Reactome:R-HSA-5601843|Reactome:R-HSA-193070|Reactome:R-HSA-193068|EC:1.14.14.19|Reactome:R-HSA-9035956		molecular_function											owl:Class	
GO:0008395	biolink:NamedThing	steroid hydroxylase activity	Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.	got7fsn_ti	cytochrome P450 CYP2G1|olfactory-specific steroid hydroxylase activity										GO:0008394	Reactome:R-HSA-193060|Reactome:R-HSA-6785245|Reactome:R-HSA-193497|Reactome:R-HSA-193965|Reactome:R-HSA-193713|Reactome:R-HSA-193460|Reactome:R-HSA-5602170|Reactome:R-HSA-193393|Reactome:R-HSA-5601849|Reactome:R-HSA-192042|Reactome:R-HSA-193737|Reactome:R-HSA-6785244|Reactome:R-HSA-192123|Reactome:R-HSA-193780|Reactome:R-HSA-192054|Reactome:R-HSA-193995|RHEA:43836|Reactome:R-HSA-193787|Reactome:R-HSA-191999|Reactome:R-HSA-9035960|Reactome:R-HSA-193143|Reactome:R-HSA-193719|Reactome:R-HSA-193792|Reactome:R-HSA-191983		molecular_function											owl:Class	
GO:0097632	biolink:NamedThing	extrinsic component of phagophore assembly site membrane	The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to phagophore assembly site membrane|extrinsic component of pre-autophagosomal structure membrane|phagophore assembly site peripheral membrane													cellular_component											owl:Class	
GO:0031312	biolink:NamedThing	extrinsic component of organelle membrane	The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to organelle membrane													cellular_component											owl:Class	
GO:0006955	biolink:NamedThing	immune response	Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.	got7fsn_ti														biological_process											owl:Class	
GO:0050961	biolink:NamedThing	detection of temperature stimulus involved in sensory perception	The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.	got7fsn_ti	sensory detection of temperature stimulus|sensory perception, sensory transduction of heat stimulus|sensory perception, sensory detection of thermal stimulus|sensory perception, sensory transduction of temperature stimulus|sensory transduction of temperature stimulus|sensory detection of heat stimulus during sensory perception|sensory perception, sensory detection of heat stimulus|sensory transduction of thermal stimulus during sensory perception|sensory detection of thermal stimulus during sensory perception|sensory transduction of temperature stimulus during sensory perception|sensory transduction of heat stimulus during sensory perception|sensory detection of temperature stimulus during sensory perception|sensory perception, sensory detection of temperature stimulus|sensory perception, sensory transduction of thermal stimulus													biological_process											owl:Class	
GO:0050906	biolink:NamedThing	detection of stimulus involved in sensory perception	The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.	got7fsn_ti	sensory perception, sensory transduction of stimulus|sensory detection of stimulus|sensory perception, stimulus detection|sensory transduction											Wikipedia:Transduction_(physiology)		biological_process											owl:Class	
GO:0061223	biolink:NamedThing	mesonephric mesenchymal cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.	got7fsn_ti							dph	2010-08-19T01:21:48Z						biological_process											owl:Class	
GO:0061208	biolink:NamedThing	cell differentiation involved in mesonephros development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.	got7fsn_ti							dph	2010-08-17T03:21:23Z						biological_process											owl:Class	
GO:0061198	biolink:NamedThing	fungiform papilla formation	The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.	got7fsn_ti							dph	2010-07-27T12:29:03Z						biological_process											owl:Class	
GO:0048871	biolink:NamedThing	multicellular organismal homeostasis	Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.	got7fsn_ti														biological_process											owl:Class	
GO:0042592	biolink:NamedThing	homeostatic process	Any biological process involved in the maintenance of an internal steady state.	got7fsn_ti	homeostasis|regulation of homeostatic process|positive regulation of homeostatic process|negative regulation of homeostatic process|inhibition of homeostatic process|activation of homeostatic process										GO:0032846|GO:0032844|GO:0032845			biological_process											owl:Class	
GO:0010366	biolink:NamedThing	negative regulation of ethylene biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process.	got7fsn_ti														biological_process											owl:Class	
GO:0031336	biolink:NamedThing	negative regulation of sulfur amino acid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.	got7fsn_ti	down-regulation of sulfur amino acid metabolic process|downregulation of sulfur amino acid metabolic process|negative regulation of sulfur amino acid metabolism|down regulation of sulfur amino acid metabolic process|inhibition of sulfur amino acid metabolic process													biological_process											owl:Class	
GO:0017042	biolink:NamedThing	glycosylceramidase activity	Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine.	got7fsn_ti	phloretin-glucosidase activity|lactase-phlorizin hydrolase|cerebrosidase activity|phlorizin hydrolase activity|glycosyl-N-acylsphingosine glycohydrolase activity|phloridzin glucosidase activity|phloridzin beta-glucosidase activity|glycosyl ceramide glycosylhydrolase activity											EC:3.2.1.62|MetaCyc:GLYCOSYLCERAMIDASE-RXN		molecular_function											owl:Class	
GO:0060454	biolink:NamedThing	positive regulation of gastric acid secretion	Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.	got7fsn_ti														biological_process											owl:Class	
GO:0061355	biolink:NamedThing	Wnt protein secretion	The controlled release of a Wnt protein from a cell.	got7fsn_ti							dph	2010-10-08T01:07:48Z						biological_process											owl:Class	
GO:0009306	biolink:NamedThing	protein secretion	The controlled release of proteins from a cell.	got7fsn_ti	protein secretion resulting in cell fate commitment|glycoprotein secretion|protein secretion during cell fate commitment										GO:0045731|GO:0045166			biological_process											owl:Class	
GO:1990185	biolink:NamedThing	regulation of lymphatic vascular permeability	Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.	got7fsn_ti							sl	2013-09-11T15:36:22Z						biological_process											owl:Class	
GO:2000874	biolink:NamedThing	regulation of glyoxylate cycle	Any process that modulates the frequency, rate or extent of glyoxylate cycle.	got7fsn_ti	regulation of glyoxylate bypass						bf	2011-07-27T01:27:10Z						biological_process											owl:Class	
GO:0050519	biolink:NamedThing	holo-citrate lyase synthase activity	Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase.	got7fsn_ti	CitX|2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase activity|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase activity|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase activity|holo-ACP synthase activity											RHEA:16333|MetaCyc:2.7.7.61-RXN|EC:2.7.7.61		molecular_function											owl:Class	
GO:0016779	biolink:NamedThing	nucleotidyltransferase activity	Catalysis of the transfer of a nucleotidyl group to a reactant.	got7fsn_ti												Reactome:R-HSA-6782434|EC:2.7.7.-		molecular_function											owl:Class	
GO:1990883	biolink:NamedThing	rRNA cytidine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA.	got7fsn_ti							al	2015-10-28T13:27:35Z						molecular_function											owl:Class	
GO:0008080	biolink:NamedThing	N-acetyltransferase activity	Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.	got7fsn_ti												Reactome:R-HSA-2473152|Reactome:R-HSA-9636560|Reactome:R-HSA-6790987|Reactome:R-HSA-2468039		molecular_function											owl:Class	
GO:0009896	biolink:NamedThing	positive regulation of catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.	got7fsn_ti	positive regulation of breakdown|activation of catabolic process|stimulation of catabolic process|up regulation of catabolic process|positive regulation of catabolism|up-regulation of catabolic process|positive regulation of degradation|upregulation of catabolic process													biological_process											owl:Class	
GO:0009893	biolink:NamedThing	positive regulation of metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.	got7fsn_ti	up-regulation of organismal metabolic process|positive regulation of multicellular organismal metabolic process|positive regulation of organismal metabolism|activation of metabolic process|stimulation of organismal metabolic process|upregulation of metabolic process|positive regulation of metabolism|up-regulation of metabolic process|up regulation of metabolic process|stimulation of metabolic process										GO:0044253			biological_process											owl:Class	
GO:0030982	biolink:NamedThing	adventurous gliding motility	A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime.	got7fsn_ti	adventurous gliding movement													biological_process											owl:Class	
GO:0071976	biolink:NamedThing	cell gliding	Cell motility that results in the smooth movement of a cell along a solid surface.	got7fsn_ti	cell gliding motility						mah	2010-10-21T02:33:24Z						biological_process											owl:Class	
GO:0052869	biolink:NamedThing	arachidonic acid omega-hydroxylase activity	Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid.	got7fsn_ti	arachidonic acid hydroxylase activity|arachidonic acid:oxygen 1-oxidoreductase activity						ai	2012-01-30T03:05:27Z				KEGG_REACTION:R07041|EC:1.14.15.3		molecular_function											owl:Class	
GO:0002046	biolink:NamedThing	opsin binding	Binding to an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.	got7fsn_ti	metarhodopsin binding										GO:0016030			molecular_function											owl:Class	
GO:0019139	biolink:NamedThing	cytokinin dehydrogenase activity	Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.	got7fsn_ti	N6-dimethylallyladenine:acceptor oxidoreductase activity|6-N-dimethylallyladenine:acceptor oxidoreductase activity|cytokinin oxidase activity|N6-dimethylallyladenine:(acceptor) oxidoreductase activity										GO:0046420	EC:1.5.99.12|RHEA:13625|MetaCyc:PWY-2841|MetaCyc:1.5.99.12-RXN		molecular_function											owl:Class	
GO:0016645	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on the CH-NH group of donors, other acceptors											EC:1.5.-.-		molecular_function											owl:Class	
GO:0052076	biolink:NamedThing	induction by symbiont of host ethylene-mediated defense response	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	up-regulation by symbiont of host ethylene-mediated defense response|positive regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|stimulation by symbiont of host ethylene-mediated defense response|positive regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host ethylene-mediated defense response|positive regulation by symbiont of host ethylene-mediated defense response|activation by symbiont of host ethylene-mediated defense response|upregulation by symbiont of host ethylene-mediated defense response|positive regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway										GO:0052269|GO:0052274|GO:0052071			biological_process											owl:Class	
GO:0052028	biolink:NamedThing	induction by symbiont of host signal transduction pathway	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	stimulation by symbiont of host signal transduction pathway|up regulation by symbiont of host signal transduction pathway|upregulation by symbiont of host signal transduction pathway|up-regulation by symbiont of host signal transduction pathway|activation by symbiont of host signal transduction pathway|positive regulation of signal transduction in other organism|positive regulation by organism of signal transduction in other organism involved in symbiotic interaction|positive regulation by symbiont of host signal transduction pathway										GO:0052526|GO:0044502			biological_process											owl:Class	
GO:0102941	biolink:NamedThing	3,5-dihydroxyanisole O-methyltransferase activity	Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine  = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-9021		molecular_function											owl:Class	
GO:0047043	biolink:NamedThing	3-alpha-hydroxycholanate dehydrogenase activity	Catalysis of the reaction: lithocholate + NAD(+) = 3-oxo-5beta-cholanate + H(+) + NADH.	got7fsn_ti	alpha-hydroxy-cholanate dehydrogenase activity|3alpha-hydroxycholanate dehydrogenase activity|3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase activity											MetaCyc:1.1.1.52-RXN|KEGG_REACTION:R04139|EC:1.1.1.52|RHEA:19585		molecular_function											owl:Class	
GO:0021506	biolink:NamedThing	anterior neuropore closure	The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.	got7fsn_ti														biological_process											owl:Class	
GO:0016331	biolink:NamedThing	morphogenesis of embryonic epithelium	The process in which the anatomical structures of embryonic epithelia are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0016926	biolink:NamedThing	protein desumoylation	The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.	got7fsn_ti	protein desumolation|desumoylation										GO:0016928			biological_process											owl:Class	
GO:0070646	biolink:NamedThing	protein modification by small protein removal	A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.	got7fsn_ti							mah	2009-05-11T01:58:15Z						biological_process											owl:Class	
GO:0036220	biolink:NamedThing	ITP diphosphatase activity	Catalysis of the reaction: ITP + H2O = IMP + diphosphate.	got7fsn_ti	inosine-5'-triphosphate pyrophosphohydrolase activity						bf	2012-05-08T01:47:59Z				KEGG_REACTION:R00720|Reactome:R-HSA-2509827|RHEA:29399|MetaCyc:RXN0-6382		molecular_function											owl:Class	
GO:0047429	biolink:NamedThing	nucleoside-triphosphate diphosphatase activity	Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.	got7fsn_ti	nucleoside-triphosphate pyrophosphatase activity|nucleoside-triphosphate diphosphohydrolase activity											EC:3.6.1.9|MetaCyc:3.6.1.19-RXN		molecular_function											owl:Class	
GO:0032176	biolink:NamedThing	split septin rings	A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well.	got7fsn_ti														cellular_component											owl:Class	
GO:0032156	biolink:NamedThing	septin cytoskeleton	The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes.	got7fsn_ti														cellular_component											owl:Class	
GO:0060777	biolink:NamedThing	compound leaf morphogenesis	The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development.	got7fsn_ti							dph	2009-07-25T07:12:30Z						biological_process											owl:Class	
GO:0009965	biolink:NamedThing	leaf morphogenesis	The process in which the anatomical structures of the leaf are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0009231	biolink:NamedThing	riboflavin biosynthetic process	The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).	got7fsn_ti	vitamin G biosynthetic process|riboflavin formation|vitamin B2 biosynthesis|vitamin B2 biosynthetic process|riboflavin biosynthesis|riboflavin anabolism|vitamin G biosynthesis|riboflavin synthesis											MetaCyc:RIBOSYN2-PWY|Wikipedia:Riboflavin		biological_process											owl:Class	
GO:0042364	biolink:NamedThing	water-soluble vitamin biosynthetic process	The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water.	got7fsn_ti	water-soluble vitamin biosynthesis|water-soluble vitamin synthesis|water-soluble vitamin anabolism|water-soluble vitamin formation													biological_process											owl:Class	
GO:1990452	biolink:NamedThing	Parkin-FBXW7-Cul1 ubiquitin ligase complex	A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.	got7fsn_ti	Parkin-HSel-10-Cullin-1 complex|PRKN-FBXW7-Cul1 complex|Parkin/Cul1/F-box protein complex|Parkin-FBXW7-Cul1 protein complex|Park2-FBXW7-Cul1 complex						bf	2014-08-07T14:25:49Z						cellular_component											owl:Class	
GO:0000151	biolink:NamedThing	ubiquitin ligase complex	A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0018397	biolink:NamedThing	peptidyl-phenylalanine bromination to L-2'-bromophenylalanine	The bromination of peptidyl-phenylalanine to form L-2'-bromophenylalanine.	got7fsn_ti												RESID:AA0174		biological_process											owl:Class	
GO:0018075	biolink:NamedThing	peptidyl-phenylalanine bromination	The bromination of phenylalanine.	got7fsn_ti												RESID:AA0175|RESID:AA0174|RESID:AA0176		biological_process											owl:Class	
GO:0003013	biolink:NamedThing	circulatory system process	A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.	got7fsn_ti												Wikipedia:Circulatory_system		biological_process											owl:Class	
GO:0007128	biolink:NamedThing	meiotic prophase I	The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0051324	biolink:NamedThing	prophase	The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Prophase		biological_process											owl:Class	
GO:0021527	biolink:NamedThing	spinal cord association neuron differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti	spinal cord dorsal interneuron differentiation													biological_process											owl:Class	
GO:0021515	biolink:NamedThing	cell differentiation in spinal cord	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0120119	biolink:NamedThing	flagellum attachment zone	A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.	got7fsn_ti	FAZ				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use.		krc	2017-12-11T22:46:43Z						cellular_component											owl:Class	
GO:0070161	biolink:NamedThing	anchoring junction	A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.	got7fsn_ti	anchoring cell junction													cellular_component											owl:Class	
GO:0000708	biolink:NamedThing	meiotic strand invasion	The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.	got7fsn_ti	meiotic displacement loop formation|meiotic displacement loop biosynthesis|meiotic D-loop biosynthesis|meiotic D-loop formation													biological_process											owl:Class	
GO:0042148	biolink:NamedThing	strand invasion	The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.	got7fsn_ti	D-loop formation|displacement loop biosynthesis|Rad51-mediated strand invasion|D-loop biosynthesis|displacement loop formation													biological_process											owl:Class	
GO:0016598	biolink:NamedThing	protein arginylation	The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.	got7fsn_ti	protein amino acid arginylation										GO:0019130			biological_process											owl:Class	
GO:0006464	biolink:NamedThing	cellular protein modification process	The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).	got7fsn_ti	protein tagging activity|process resulting in protein modification|protein modification process													biological_process											owl:Class	
GO:0031571	biolink:NamedThing	mitotic G1 DNA damage checkpoint signaling	A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.	got7fsn_ti	intracellular signal transduction pathway involved in G1 DNA damage checkpoint|intracellular signaling chain involved in G1/S DNA damage checkpoint|intracellular signal transduction involved in G1 DNA damage checkpoint|intracellular signaling pathway involved in G1 DNA damage checkpoint|signal transmission via intracellular cascade involved in G1 DNA damage checkpoint|intracellular signal transduction involved in G1/S DNA damage checkpoint|intracellular signaling pathway involved in G1/S DNA damage checkpoint|G1/S DNA damage checkpoint|intracellular signaling cascade involved in G1 DNA damage checkpoint|intracellular signaling chain involved in G1 DNA damage checkpoint|G1 DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in G1/S DNA damage checkpoint|signal transduction involved in mitotic G1 DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint|intracellular signal transduction pathway involved in G1/S DNA damage checkpoint|mitotic G1 DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in G1 DNA damage checkpoint|intracellular signaling cascade involved in G1/S DNA damage checkpoint										GO:0044783|GO:0072431|GO:1902400			biological_process											owl:Class	
GO:0044819	biolink:NamedThing	mitotic G1/S transition checkpoint signaling	A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.	got7fsn_ti	mitotic G1/S transition checkpoint	https://github.com/geneontology/go-ontology/issues/20935					jl	2013-11-19T14:31:14Z						biological_process											owl:Class	
GO:0048518	biolink:NamedThing	positive regulation of biological process	Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.	got7fsn_ti	activation of biological process|upregulation of biological process|positive regulation of physiological process|up regulation of biological process|up-regulation of biological process|stimulation of biological process										GO:0043119			biological_process											owl:Class	
GO:0005852	biolink:NamedThing	eukaryotic translation initiation factor 3 complex	A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.	got7fsn_ti	eIF-3|eIF3													cellular_component											owl:Class	
GO:0018188	biolink:NamedThing	peptidyl-proline di-hydroxylation	The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline.	got7fsn_ti												RESID:AA0282		biological_process											owl:Class	
GO:0019511	biolink:NamedThing	peptidyl-proline hydroxylation	The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.	got7fsn_ti											GO:0006472			biological_process											owl:Class	
GO:0005385	biolink:NamedThing	zinc ion transmembrane transporter activity	Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.	got7fsn_ti	cobalt, zinc uptake permease activity|zinc, cadmium uptake permease activity|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|zinc, iron permease activity											Reactome:R-HSA-442422|Reactome:R-HSA-437136|Reactome:R-HSA-437084|Reactome:R-HSA-435375|RHEA:29351|Reactome:R-HSA-442345|Reactome:R-HSA-435366|Reactome:R-HSA-437139|Reactome:R-HSA-442405|Reactome:R-HSA-437085|Reactome:R-HSA-442393|Reactome:R-HSA-437129|Reactome:R-HSA-442387|Reactome:R-HSA-5654125|Reactome:R-HSA-442317		molecular_function											owl:Class	
GO:0022890	biolink:NamedThing	inorganic cation transmembrane transporter activity	Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.	got7fsn_ti	monovalent inorganic cation transmembrane transporter activity|trivalent inorganic cation transmembrane transporter activity|di-, tri-valent inorganic cation transmembrane transporter activity|divalent inorganic cation transmembrane transporter activity										GO:0015082|GO:0015077|GO:0072509|GO:0072510			molecular_function											owl:Class	
GO:0003046	biolink:NamedThing	regulation of systemic arterial blood pressure by stress relaxation	The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.	got7fsn_ti	blood pressure regulation by stress relaxation													biological_process											owl:Class	
GO:0003085	biolink:NamedThing	negative regulation of systemic arterial blood pressure	The process that reduces the force with which blood travels through the systemic arterial circulatory system.	got7fsn_ti														biological_process											owl:Class	
GO:0002468	biolink:NamedThing	dendritic cell antigen processing and presentation	The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0044080	biolink:NamedThing	modulation by symbiont of host cGMP-mediated signal transduction	Any process in which a symbiont organism modulates the rate, frequency or extent of cGMP-mediated signaling in its host organism. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.	got7fsn_ti	modulation by symbiont of host cGMP-mediated signaling|regulation by symbiont of host cGMP-mediated signal transduction|modulation of host cGMP-mediated signal transduction by symbiont|modulation by symbiont of host cGMP-mediated signalling|modulation by symbiont of host cGMP-mediated signal transduction pathway													biological_process											owl:Class	
GO:0010752	biolink:NamedThing	regulation of cGMP-mediated signaling	Any process that modulates the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.	got7fsn_ti	regulation of cGMP-mediated signalling													biological_process											owl:Class	
GO:0045605	biolink:NamedThing	negative regulation of epidermal cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.	got7fsn_ti	down-regulation of epidermal cell differentiation|inhibition of epidermal cell differentiation|downregulation of epidermal cell differentiation|negative regulation of hypodermal cell differentiation|down regulation of epidermal cell differentiation													biological_process											owl:Class	
GO:0045683	biolink:NamedThing	negative regulation of epidermis development	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development.	got7fsn_ti	down regulation of epidermis development|negative regulation of epidermal development|negative regulation of hypodermis development|downregulation of epidermis development|down-regulation of epidermis development|inhibition of epidermis development													biological_process											owl:Class	
GO:0043330	biolink:NamedThing	response to exogenous dsRNA	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.	got7fsn_ti	response to viral dsRNA|response to exogenous double-stranded RNA				Note that the presence of exogenous double-stranded RNA is usually indicative of a viral infection. Consider also annotating to 'response to virus ; GO:0009615'.									biological_process											owl:Class	
GO:0043331	biolink:NamedThing	response to dsRNA	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.	got7fsn_ti	response to double-stranded RNA													biological_process											owl:Class	
GO:0048446	biolink:NamedThing	petal morphogenesis	The process in which the anatomical structures of the petal are generated and organized.	got7fsn_ti											GO:0048418			biological_process											owl:Class	
GO:0048444	biolink:NamedThing	floral organ morphogenesis	The process in which the anatomical structures of the floral organ are generated and organized.	got7fsn_ti											GO:0048434			biological_process											owl:Class	
GO:0061648	biolink:NamedThing	tooth replacement	The process whose specific outcome is the replacement of an existing tooth with another tooth.	got7fsn_ti							dph	2014-10-02T15:26:53Z						biological_process											owl:Class	
GO:0042476	biolink:NamedThing	odontogenesis	The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.	got7fsn_ti	tooth development|odontogeny|tooth morphogenesis|odontogenesis of calcareous or chitinous tooth|odontosis										GO:0042477	Wikipedia:Odontogenesis		biological_process											owl:Class	
GO:0043480	biolink:NamedThing	pigment accumulation in tissues	The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.	got7fsn_ti	organismal pigment accumulation													biological_process											owl:Class	
GO:0052170	biolink:NamedThing	suppression by symbiont of host innate immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of host innate immune response|negative regulation by symbiont of host innate immunity|down regulation by symbiont of host innate immunity|inhibition by symbiont of host innate immunity|negative regulation by symbiont of host innate immune response|downregulation by symbiont of host innate immunity|down-regulation by symbiont of host innate immunity|negative regulation of innate immune response in other organism										GO:0052309			biological_process											owl:Class	
GO:0052562	biolink:NamedThing	suppression by symbiont of host immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	down-regulation by symbiont of host immune response|inhibition by symbiont of host immune response|negative regulation by symbiont of host immune response|negative regulation by organism of immune response of other organism involved in symbiotic interaction|downregulation by symbiont of host immune response|down regulation by symbiont of host immune response										GO:0052561			biological_process											owl:Class	
GO:0036375	biolink:NamedThing	Kibra-Ex-Mer complex	An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2.	got7fsn_ti	Kbr, Ex and Mer complex|KEM complex						bf	2013-05-07T10:05:15Z						cellular_component											owl:Class	
GO:0070357	biolink:NamedThing	alphav-beta3 integrin-CD47 complex	A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP).	got7fsn_ti	ITGB3-ITGAV-CD47 complex													cellular_component											owl:Class	
GO:1990065	biolink:NamedThing	Dxr protein complex	A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).	got7fsn_ti	1-deoxy-D-xylulose 5-phosphate reductoisomerase complex						bhm	2013-03-27T16:58:54Z						cellular_component											owl:Class	
GO:0036028	biolink:NamedThing	protein C inhibitor-thrombin complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin.	got7fsn_ti	serpin A5-thrombin complex|plasma serine protease inhibitor-thrombin complex|PCI-thrombin complex|protein C inhibitor-coagulation factor II complex|protein C inhibitor-F2 complex|SERPINA5-thrombin complex						bf	2011-10-19T01:40:18Z						cellular_component											owl:Class	
GO:0097180	biolink:NamedThing	serine protease inhibitor complex	A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity.	got7fsn_ti	serine-type endopeptidase inhibitor complex|serpin complex						pr	2011-10-16T08:55:17Z						cellular_component											owl:Class	
GO:0036025	biolink:NamedThing	protein C inhibitor-TMPRSS11E complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E.	got7fsn_ti	PCI-TMPRSS11E complex|SERPINA5-TMPRSS11E complex|plasma serine protease inhibitor-TMPRSS11E complex|serpin A5-TMPRSS11E complex|protein C inhibitor-transmembrane protease serine 11E complex						bf	2011-10-19T01:29:08Z						cellular_component											owl:Class	
GO:0002205	biolink:NamedThing	somatic hypermutation of immunoglobulin genes involved in immune response	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response.	got7fsn_ti	somatic hypermutation of immunoglobulin genes during immune response|somatic hypermutation of antibody genes during immune response													biological_process											owl:Class	
GO:0016446	biolink:NamedThing	somatic hypermutation of immunoglobulin genes	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.	got7fsn_ti	somatic hypermutation of antibody genes													biological_process											owl:Class	
GO:0030649	biolink:NamedThing	aminoglycoside antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.	got7fsn_ti	aminoglycoside antibiotic degradation|aminoglycoside antibiotic breakdown|aminoglycoside antibiotic catabolism													biological_process											owl:Class	
GO:0017001	biolink:NamedThing	antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.	got7fsn_ti	antibiotic catabolism|antibiotic degradation|antibiotic breakdown													biological_process											owl:Class	
GO:0035132	biolink:NamedThing	post-embryonic medial fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.	got7fsn_ti	post-embryonic unpaired fin morphogenesis													biological_process											owl:Class	
GO:0035120	biolink:NamedThing	post-embryonic appendage morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.	got7fsn_ti														biological_process											owl:Class	
GO:0035622	biolink:NamedThing	intrahepatic bile duct development	The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).	got7fsn_ti	IHBD development|intrahepatic biliary duct development						bf	2010-12-08T04:10:50Z						biological_process											owl:Class	
GO:0061827	biolink:NamedThing	sperm head	The part of the late spermatid or spermatozoon that contains the nucleus and acrosome.	got7fsn_ti							dph	2017-01-15T10:39:00Z						cellular_component											owl:Class	
GO:0098518	biolink:NamedThing	polynucleotide phosphatase activity	Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate.	got7fsn_ti							dos	2013-09-26T11:02:35Z						molecular_function											owl:Class	
GO:0010374	biolink:NamedThing	stomatal complex development	The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells.	got7fsn_ti														biological_process											owl:Class	
GO:0032200	biolink:NamedThing	telomere organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.	got7fsn_ti	organization of chromosome, telomeric region|telomere organization and biogenesis|telomere organisation|chromosome organization, telomeric													biological_process											owl:Class	
GO:0051276	biolink:NamedThing	chromosome organization	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.	got7fsn_ti	maintenance of genome integrity|chromosome organization and biogenesis|nuclear genome maintenance|chromosome organisation										GO:0051277|GO:0007001			biological_process											owl:Class	
GO:0033103	biolink:NamedThing	protein secretion by the type VI secretion system	The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.	got7fsn_ti	protein secretion by the T6SS|type VI protein secretion system|protein secretion by the type VI protein secretion system				Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type VI protein secretion system complex ; GO:0033104'.									biological_process											owl:Class	
GO:0047961	biolink:NamedThing	glycine N-acyltransferase activity	Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine.	got7fsn_ti	acyl-CoA:glycine N-acyltransferase activity|glycine acyltransferase activity|glycine-N-acylase activity											MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN|RHEA:19869|EC:2.3.1.13|Reactome:R-HSA-2534040		molecular_function											owl:Class	
GO:0030175	biolink:NamedThing	filopodium	Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.	got7fsn_ti					A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.						GO:0030028	NIF_Subcellular:sao1046371754|Wikipedia:Filopodia		cellular_component											owl:Class	
GO:0098858	biolink:NamedThing	actin-based cell projection	A cell projection supported by an assembly of actin filaments, and which lacks microtubules.	got7fsn_ti														cellular_component											owl:Class	
GO:0032341	biolink:NamedThing	aldosterone metabolic process	The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.	got7fsn_ti	aldosterone metabolism													biological_process											owl:Class	
GO:0008207	biolink:NamedThing	C21-steroid hormone metabolic process	The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.	got7fsn_ti	C21-steroid hormone metabolism													biological_process											owl:Class	
GO:0035993	biolink:NamedThing	deltoid tuberosity development	The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.	got7fsn_ti							bf	2011-08-30T01:46:53Z						biological_process											owl:Class	
GO:0018725	biolink:NamedThing	trans-3,4-dihydrodiolphenanthrene sulfotransferase activity	Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate.	got7fsn_ti	trans-3,4-dihydrodiolphenanthrene sulphotransferase activity											UM-BBD_reactionID:r0558		molecular_function											owl:Class	
GO:0071261	biolink:NamedThing	Ssh1 translocon complex	A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.	got7fsn_ti	Ssh1p-Sss1p-Sbh2p complex						mah	2009-12-08T02:22:55Z						cellular_component											owl:Class	
GO:0071256	biolink:NamedThing	translocon complex	A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.	got7fsn_ti	Sec complex-associated translocon complex						mah	2009-12-08T02:08:03Z			GO:0031206			cellular_component											owl:Class	
GO:0040019	biolink:NamedThing	positive regulation of embryonic development	Any process that activates or increases the frequency, rate or extent of embryonic development.	got7fsn_ti	up-regulation of embryonic development|stimulation of embryonic development|upregulation of embryonic development|up regulation of embryonic development|activation of embryonic development													biological_process											owl:Class	
GO:0051094	biolink:NamedThing	positive regulation of developmental process	Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	got7fsn_ti	activation of developmental process|stimulation of developmental process|up-regulation of developmental process|upregulation of developmental process|up regulation of developmental process													biological_process											owl:Class	
GO:0048098	biolink:NamedThing	antennal joint development	The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments.	got7fsn_ti														biological_process											owl:Class	
GO:0042128	biolink:NamedThing	nitrate assimilation	The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.	got7fsn_ti	assimilatory nitrate reduction											MetaCyc:PWY-381		biological_process											owl:Class	
GO:0071941	biolink:NamedThing	nitrogen cycle metabolic process	A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.	got7fsn_ti							mah	2010-09-30T05:21:03Z				Wikipedia:Nitrogen_cycle		biological_process											owl:Class	
GO:0050639	biolink:NamedThing	10-hydroxytaxane O-acetyltransferase activity	Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C.	got7fsn_ti	acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase activity|acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase activity|acetyl-CoA:taxan-10beta-ol O-acetyltransferase											EC:2.3.1.163|MetaCyc:2.3.1.163-RXN|RHEA:18837|KEGG_REACTION:R07252		molecular_function											owl:Class	
GO:1902105	biolink:NamedThing	regulation of leukocyte differentiation	Any process that modulates the frequency, rate or extent of leukocyte differentiation.	got7fsn_ti	regulation of immune cell differentiation|regulation of leucocyte differentiation						pr	2013-05-02T17:32:42Z						biological_process											owl:Class	
GO:0045595	biolink:NamedThing	regulation of cell differentiation	Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.	got7fsn_ti														biological_process											owl:Class	
GO:0004956	biolink:NamedThing	prostaglandin D receptor activity	Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.	got7fsn_ti	PGD receptor activity|PGD(2) receptor activity													molecular_function											owl:Class	
GO:0004955	biolink:NamedThing	prostaglandin receptor activity	Combining with a prostaglandin (PG) to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0016217	biolink:NamedThing	N-ethylammeline chlorohydrolase activity	Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+.	got7fsn_ti												MetaCyc:R465-RXN		molecular_function											owl:Class	
GO:0019120	biolink:NamedThing	hydrolase activity, acting on acid halide bonds, in C-halide compounds	Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage.	got7fsn_ti												Reactome:R-HSA-9011595|EC:3.8.1.-		molecular_function											owl:Class	
GO:0070065	biolink:NamedThing	cellubrevin-VAMP4-syntaxin-16 complex	A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof).	got7fsn_ti	Vamp3-Vamp4-Stx16 complex|SNARE complex (Vamp3, Vamp4, Stx16)													cellular_component											owl:Class	
GO:0031201	biolink:NamedThing	SNARE complex	A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.	got7fsn_ti														cellular_component											owl:Class	
GO:0090565	biolink:NamedThing	protein-phosphocysteine-mannitol phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti							tb	2014-04-08T15:03:08Z						molecular_function											owl:Class	
GO:0090563	biolink:NamedThing	protein-phosphocysteine-sugar phosphotransferase activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti							tb	2014-04-08T14:58:00Z						molecular_function											owl:Class	
GO:0099610	biolink:NamedThing	action potential initiation	The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.	got7fsn_ti	action potential firing|action potential triggering													biological_process											owl:Class	
GO:0001508	biolink:NamedThing	action potential	A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.	got7fsn_ti					Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so.									biological_process											owl:Class	
GO:0030629	biolink:NamedThing	U6 snRNA 3'-end binding	Binding to a U6 small nuclear RNA (U6 snRNA) at the 3' end.	got7fsn_ti	U6 snRNA 3' end binding				Note that this term may be useful for annotating small nuclear RNAs (snRNAs).									molecular_function											owl:Class	
GO:0017070	biolink:NamedThing	U6 snRNA binding	Binding to a U6 small nuclear RNA (U6 snRNA).	got7fsn_ti														molecular_function											owl:Class	
GO:1990428	biolink:NamedThing	miRNA transport	The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.	got7fsn_ti	microRNA transport						jl	2014-07-29T14:03:46Z						biological_process											owl:Class	
GO:0050658	biolink:NamedThing	RNA transport	The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0051468	biolink:NamedThing	detection of glucocorticoid hormone stimulus	The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.	got7fsn_ti														biological_process											owl:Class	
GO:0051384	biolink:NamedThing	response to glucocorticoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.	got7fsn_ti	response to glucocorticoid stimulus													biological_process											owl:Class	
GO:0099015	biolink:NamedThing	degradation of host chromosome by virus	The catabolic breakdown of the DNA of a host chromosome by a virus.  This occurs during infection of bacteria by some phages.  It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis.	got7fsn_ti												VZ:3947		biological_process											owl:Class	
GO:0039637	biolink:NamedThing	catabolism by virus of host DNA	The breakdown of host DNA, deoxyribonucleic acid, by a virus.	got7fsn_ti							bf	2012-08-10T15:59:22Z						biological_process											owl:Class	
GO:0061681	biolink:NamedThing	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate.	got7fsn_ti							dph	2015-01-22T08:55:22Z				MetaCyc:ENTNER-DOUDOROFF-PWY-III		biological_process											owl:Class	
GO:0061679	biolink:NamedThing	Entner-Doudoroff pathway through gluconate	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate.	got7fsn_ti	gluconate pathway						dph	2015-01-16T15:41:22Z						biological_process											owl:Class	
GO:0044525	biolink:NamedThing	peptidyl-cystine sulfhydration	The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide.	got7fsn_ti							jl	2012-03-15T09:44:07Z						biological_process											owl:Class	
GO:0044524	biolink:NamedThing	protein sulfhydration	The modification of a protein amino acid by the addition of sulfur.	got7fsn_ti							jl	2012-03-15T09:39:33Z						biological_process											owl:Class	
GO:0086073	biolink:NamedThing	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	got7fsn_ti							dph	2011-11-22T10:00:30Z						biological_process											owl:Class	
GO:0034113	biolink:NamedThing	heterotypic cell-cell adhesion	The attachment of a cell to a cell of a different type via adhesion molecules.	got7fsn_ti					Note that this term is not synonymous with 'heterophilic cell adhesion ; GO:0007157'; the process may occur by homophilic or heterophilic mechanisms.									biological_process											owl:Class	
GO:0007339	biolink:NamedThing	binding of sperm to zona pellucida	The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.	got7fsn_ti	ZPG binding													biological_process											owl:Class	
GO:0035036	biolink:NamedThing	sperm-egg recognition	The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.	got7fsn_ti														biological_process											owl:Class	
GO:1903042	biolink:NamedThing	negative regulation of chondrocyte hypertrophy	Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.	got7fsn_ti	down regulation of chondrocyte hypertrophy|inhibition of chondrocyte hypertrophy|down-regulation of chondrocyte hypertrophy|downregulation of chondrocyte hypertrophy						mr	2014-05-20T21:23:19Z						biological_process											owl:Class	
GO:0042861	biolink:NamedThing	achromobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore.	got7fsn_ti	achromobactin anabolism|achromobactin formation|achromobactin synthesis|achromobactin biosynthesis										GO:0031182|GO:0031181			biological_process											owl:Class	
GO:0019290	biolink:NamedThing	siderophore biosynthetic process	The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.	got7fsn_ti	siderophore biosynthetic process, peptide formation|siderophore biosynthesis|siderochrome biosynthetic process|siderophore anabolism|siderophore formation|siderochrome biosynthesis|siderophore synthesis|siderophore biosynthetic process, peptide modification										GO:0031180|GO:0031178			biological_process											owl:Class	
GO:0032076	biolink:NamedThing	negative regulation of deoxyribonuclease activity	Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.	got7fsn_ti	downregulation of deoxyribonuclease activity|deoxyribonuclease inhibitor|down regulation of deoxyribonuclease activity|inhibition of deoxyribonuclease activity|DNase inhibitor|down-regulation of deoxyribonuclease activity													biological_process											owl:Class	
GO:0051053	biolink:NamedThing	negative regulation of DNA metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.	got7fsn_ti	inhibition of DNA metabolic process|down-regulation of DNA metabolic process|negative regulation of DNA metabolism|down regulation of DNA metabolic process|downregulation of DNA metabolic process													biological_process											owl:Class	
GO:0102144	biolink:NamedThing	carboxyspermidine dehydrogenase II activity	Catalysis of the reaction: carboxyspermidine + H2O + NADP <=> L-aspartic acid 4-semialdehyde betaine + 1,4-butanediammonium + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-11566|RHEA:34111		molecular_function											owl:Class	
GO:0044839	biolink:NamedThing	cell cycle G2/M phase transition	The cell cycle process by which a cell in G2 phase commits to M phase.	got7fsn_ti							jl	2014-03-05T14:56:45Z						biological_process											owl:Class	
GO:0044770	biolink:NamedThing	cell cycle phase transition	The cell cycle process by which a cell commits to entering the next cell cycle phase.	got7fsn_ti	cell cycle transition						jl	2013-02-28T12:54:59Z						biological_process											owl:Class	
GO:0050845	biolink:NamedThing	teichuronic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.	got7fsn_ti	teichuronic acid anabolism|teichuronic acid biosynthesis|teichuronic acid formation|teichuronic acid synthesis													biological_process											owl:Class	
GO:0016053	biolink:NamedThing	organic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.	got7fsn_ti	organic acid biosynthesis|organic acid formation|organic acid synthesis|organic acid anabolism													biological_process											owl:Class	
GO:0002240	biolink:NamedThing	response to molecule of oomycetes origin	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.	got7fsn_ti	response to oomycetes associated molecule													biological_process											owl:Class	
GO:0010033	biolink:NamedThing	response to organic substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.	got7fsn_ti	process resulting in tolerance to organic substance										GO:1990367			biological_process											owl:Class	
GO:0016775	biolink:NamedThing	phosphotransferase activity, nitrogenous group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).	got7fsn_ti												EC:2.7.3.-		molecular_function											owl:Class	
GO:0016772	biolink:NamedThing	transferase activity, transferring phosphorus-containing groups	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).	got7fsn_ti					Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.							EC:2.7.-.-		molecular_function											owl:Class	
GO:0033142	biolink:NamedThing	progesterone receptor binding	Binding to a progesterone receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0016922	biolink:NamedThing	nuclear receptor binding	Binding to a nuclear receptor protein. Nuclear receptor proteins are DNA-binding transcription factors which are regulated by binding to a ligand.	got7fsn_ti	steroid hormone receptor binding|ligand-dependent nuclear receptor binding|nuclear hormone receptor binding|ligand-dependent nuclear receptor interactor activity										GO:0035257|GO:0035258			molecular_function											owl:Class	
GO:0120223	biolink:NamedThing	larynx morphogenesis	The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.	got7fsn_ti	laryngeal morphogenesis						krc	2020-02-22T01:42:04Z						biological_process											owl:Class	
GO:0009887	biolink:NamedThing	animal organ morphogenesis	Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti	histogenesis and organogenesis													biological_process											owl:Class	
GO:0036284	biolink:NamedThing	tubulobulbar complex	Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes.	got7fsn_ti	TBC						bf	2012-07-16T10:26:35Z						cellular_component											owl:Class	
GO:0032541	biolink:NamedThing	cortical endoplasmic reticulum	A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.	got7fsn_ti	ER-PM peripheral junction|peripheral ER|peripheral endoplasmic reticulum|cortical ER				The dynamic nature of the cortical ER and the movements it undergoes (branching and ring closure) has been shown in both yeast and mammalian cells, so appears highly conserved. (PMID:10931860)									cellular_component											owl:Class	
GO:0071782	biolink:NamedThing	endoplasmic reticulum tubular network	A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.	got7fsn_ti	ER tubular network						mah	2010-09-01T01:32:55Z						cellular_component											owl:Class	
GO:0036018	biolink:NamedThing	cellular response to erythropoietin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus.	got7fsn_ti							bf	2011-10-12T10:12:18Z						biological_process											owl:Class	
GO:0071345	biolink:NamedThing	cellular response to cytokine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.	got7fsn_ti							mah	2009-12-11T02:41:12Z						biological_process											owl:Class	
GO:0060172	biolink:NamedThing	astral microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.	got7fsn_ti														biological_process											owl:Class	
GO:0001982	biolink:NamedThing	baroreceptor response to decreased systemic arterial blood pressure	The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels.	got7fsn_ti														biological_process											owl:Class	
GO:0003084	biolink:NamedThing	positive regulation of systemic arterial blood pressure	The process that increases the force with which blood travels through the systemic arterial circulatory system.	got7fsn_ti														biological_process											owl:Class	
GO:0071603	biolink:NamedThing	endothelial cell-cell adhesion	The attachment of an endothelial cell to another endothelial cell via adhesion molecules.	got7fsn_ti							mah	2010-02-04T05:21:30Z						biological_process											owl:Class	
GO:0090136	biolink:NamedThing	epithelial cell-cell adhesion	The attachment of an epithelial cell to another epithelial cell via adhesion molecules.	got7fsn_ti							tb	2009-12-08T01:56:53Z						biological_process											owl:Class	
GO:0007523	biolink:NamedThing	larval visceral muscle development	The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0007522	biolink:NamedThing	visceral muscle development	The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0071755	biolink:NamedThing	IgM B cell receptor complex	An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	got7fsn_ti	surface IgM|membrane-bound IgM				Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0071753	biolink:NamedThing	IgM immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti					Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0008170	biolink:NamedThing	N-methyltransferase activity	Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.	got7fsn_ti												EC:2.1.1.-		molecular_function											owl:Class	
GO:0099558	biolink:NamedThing	maintenance of synapse structure	A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds.	got7fsn_ti	synaptic maintenance													biological_process											owl:Class	
GO:0050808	biolink:NamedThing	synapse organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).	got7fsn_ti	synapse organisation|synapse development|synapse organization and biogenesis|synapse morphogenesis													biological_process											owl:Class	
GO:0051363	biolink:NamedThing	peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein	The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.	got7fsn_ti					Note that this modification may be unique to the species Finegoldia (Peptostreptococcus) magnus.							RESID:AA0383		biological_process											owl:Class	
GO:0018194	biolink:NamedThing	peptidyl-alanine modification	The modification of peptidyl-alanine.	got7fsn_ti														biological_process											owl:Class	
GO:0035649	biolink:NamedThing	Nrd1 complex	A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p.	got7fsn_ti							bf	2011-01-25T10:23:25Z						cellular_component											owl:Class	
GO:0047878	biolink:NamedThing	erythritol kinase activity	Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H(+).	got7fsn_ti	ATP:erythritol 4-phosphotransferase activity|erythritol kinase (phosphorylating)											MetaCyc:ERYTHRITOL-KINASE-RXN|EC:2.7.1.27|KEGG_REACTION:R02430|RHEA:20708		molecular_function											owl:Class	
GO:0010244	biolink:NamedThing	response to low fluence blue light stimulus by blue low-fluence system	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes.	got7fsn_ti	response to low fluence blue light|response to low fluence blue light by blf system													biological_process											owl:Class	
GO:0021637	biolink:NamedThing	trigeminal nerve structural organization	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	got7fsn_ti	CN V structural organization|trigeminal nerve structural organisation													biological_process											owl:Class	
GO:0021604	biolink:NamedThing	cranial nerve structural organization	The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	got7fsn_ti	cranial nerve structural organisation													biological_process											owl:Class	
GO:0035851	biolink:NamedThing	Krueppel-associated box domain binding	Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors.	got7fsn_ti	KRAB domain binding|Krueppel-associated box binding						bf	2011-05-11T11:41:16Z						molecular_function											owl:Class	
GO:0055013	biolink:NamedThing	cardiac muscle cell development	The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.	got7fsn_ti	cardiomyocyte cell development|heart muscle cell development|heart muscle fiber development|cardiac muscle fiber development|cardiac muscle fibre development										GO:0048739			biological_process											owl:Class	
GO:0055006	biolink:NamedThing	cardiac cell development	The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.	got7fsn_ti	heart cell development|cardiocyte development													biological_process											owl:Class	
GO:0090598	biolink:NamedThing	male anatomical structure morphogenesis	The processes by which anatomical structures that are only present in the male organism are generated and organized.	got7fsn_ti							tb	2014-08-22T13:29:45Z						biological_process											owl:Class	
GO:0009653	biolink:NamedThing	anatomical structure morphogenesis	The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.	got7fsn_ti	anatomical structure organization|morphogenesis|embryogenesis and morphogenesis											Wikipedia:Morphogenesis		biological_process											owl:Class	
GO:0072558	biolink:NamedThing	NLRP1 inflammasome complex	An inflammasome complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential.	got7fsn_ti	NALP1 inflammasome complex						mah	2011-01-27T12:03:50Z						cellular_component											owl:Class	
GO:0036460	biolink:NamedThing	cellular response to cell envelope stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope.	got7fsn_ti	envelope stress response						bf	2014-01-08T15:15:50Z						biological_process											owl:Class	
GO:0009528	biolink:NamedThing	plastid inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma.	got7fsn_ti														cellular_component											owl:Class	
GO:0042170	biolink:NamedThing	plastid membrane	Either of the lipid bilayers that surround a plastid and form the plastid envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0048257	biolink:NamedThing	3'-flap endonuclease activity	Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis.	got7fsn_ti	3' flap endonuclease activity													molecular_function											owl:Class	
GO:0098735	biolink:NamedThing	positive regulation of the force of heart contraction	Any process that increases the force of heart muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0002026	biolink:NamedThing	regulation of the force of heart contraction	Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.	got7fsn_ti	heart inotropy|cardiac inotropy													biological_process											owl:Class	
GO:0006315	biolink:NamedThing	homing of group II introns	Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure.	got7fsn_ti														biological_process											owl:Class	
GO:0018666	biolink:NamedThing	2,4-dichlorophenol 6-monooxygenase activity	Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.	got7fsn_ti	2,4-dichlorophenol hydroxylase activity|2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)|2,4-dichlorophenol monooxygenase activity											EC:1.14.13.20|MetaCyc:24-DICHLOROPHENOL-6-MONOOXYGENASE-RXN|RHEA:20920|UM-BBD_enzymeID:e0152		molecular_function											owl:Class	
GO:0098736	biolink:NamedThing	negative regulation of the force of heart contraction	Any process that decreases the force of heart muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0075130	biolink:NamedThing	modulation by symbiont of host protein kinase-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075099".									biological_process											owl:Class	
GO:0052027	biolink:NamedThing	modulation by symbiont of host signal transduction pathway	Any process in which an organism modulates the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host signal transduction|modulation of host signal transduction by symbiont|modulation of signal transduction in other organism involved in symbiotic interaction|regulation by symbiont of host signal transduction pathway										GO:0052250			biological_process											owl:Class	
GO:0046565	biolink:NamedThing	3-dehydroshikimate dehydratase activity	Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.	got7fsn_ti												EC:4.2.1.118|MetaCyc:DHSHIKIMATE-DEHYDRO-RXN|RHEA:24848		molecular_function											owl:Class	
GO:0062095	biolink:NamedThing	endoplasmic reticulum-peroxisome tethering	The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other.	got7fsn_ti							dph	2018-11-21T13:28:50Z						biological_process											owl:Class	
GO:0060151	biolink:NamedThing	peroxisome localization	Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	got7fsn_ti	peroxisome localisation													biological_process											owl:Class	
GO:0009083	biolink:NamedThing	branched-chain amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.	got7fsn_ti	branched chain family amino acid degradation|branched chain family amino acid breakdown|branched chain family amino acid catabolic process|branched chain family amino acid catabolism													biological_process											owl:Class	
GO:0009063	biolink:NamedThing	cellular amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.	got7fsn_ti	cellular amino acid breakdown|amino acid catabolic process|cellular amino acid degradation|cellular amino acid catabolism													biological_process											owl:Class	
GO:0005703	biolink:NamedThing	polytene chromosome puff	A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.	got7fsn_ti														cellular_component											owl:Class	
GO:0098687	biolink:NamedThing	chromosomal region	Any subdivision of a chromosome along its length.	got7fsn_ti	chromosome region				Chromosomal regions include parts that are not part of the chromatin.  Examples include the kinetochore.									cellular_component											owl:Class	
GO:0034317	biolink:NamedThing	nicotinic acid riboside kinase activity	Catalysis of the reaction: ATP + nicotinic acid riboside = ADP + nicotinic acid mononucleotide.	got7fsn_ti												MetaCyc:RXN-8443		molecular_function											owl:Class	
GO:0019206	biolink:NamedThing	nucleoside kinase activity	Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate.	got7fsn_ti												Reactome:R-HSA-109903|Reactome:R-HSA-73598|Reactome:R-HSA-110137|Reactome:R-HSA-109671|Reactome:R-HSA-73632|Reactome:R-HSA-74207|Reactome:R-HSA-73599|Reactome:R-HSA-109759|Reactome:R-HSA-110138		molecular_function											owl:Class	
GO:0043050	biolink:NamedThing	pharyngeal pumping	The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.	got7fsn_ti	pumping behavior													biological_process											owl:Class	
GO:0042755	biolink:NamedThing	eating behavior	The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.	got7fsn_ti	eating behaviour													biological_process											owl:Class	
GO:0050240	biolink:NamedThing	pyrogallol 1,2-oxygenase activity	Catalysis of the reaction: O(2) + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H(+).	got7fsn_ti	pyrogallol 1,2-dioxygenase activity|1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing)											MetaCyc:PYROGALLOL-12-OXYGENASE-RXN|KEGG_REACTION:R03246|RHEA:19673|EC:1.13.11.35		molecular_function											owl:Class	
GO:0047212	biolink:NamedThing	2-coumarate O-beta-glucosyltransferase activity	Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H(+) + UDP.	got7fsn_ti	UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity|UDPglucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity|UDPG:o-coumaric acid O-glucosyltransferase activity|uridine diphosphoglucose-o-coumarate glucosyltransferase activity											MetaCyc:2.4.1.114-RXN|KEGG_REACTION:R03710|EC:2.4.1.114|RHEA:10236		molecular_function											owl:Class	
GO:0035251	biolink:NamedThing	UDP-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule.	got7fsn_ti												Reactome:R-HSA-1912353|MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0035747	biolink:NamedThing	natural killer cell chemotaxis	The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti							bf	2011-03-17T02:40:10Z						biological_process											owl:Class	
GO:0048247	biolink:NamedThing	lymphocyte chemotaxis	The directed movement of a lymphocyte in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0061860	biolink:NamedThing	DNA clamp unloader activity	Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex, driven by ATP hydrolysis.	got7fsn_ti							dph	2017-04-03T11:49:46Z						molecular_function											owl:Class	
GO:0008094	biolink:NamedThing	ATP-dependent activity, acting on DNA	Catalytic activity that acts to modify DNA, driven by ATP hydrolysis.	got7fsn_ti	ATPase, acting on DNA|ATPase activity, acting on DNA|DNA-dependent adenosinetriphosphatase activity|adenosinetriphosphatase (DNA-dependent)|DNA dependent ATPase activity|DNA-dependent ATPase activity	https://github.com/geneontology/go-ontology/issues/20876|https://github.com/geneontology/go-ontology/issues/21612|https://github.com/geneontology/go-ontology/issues/21775									GO:0004011			molecular_function											owl:Class	
GO:0018682	biolink:NamedThing	atrazine N-dealkylase activity	Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O.	got7fsn_ti	atrazine monooxygenase activity											MetaCyc:R461-RXN|UM-BBD_reactionID:r0127|EC:1.14.15.-		molecular_function											owl:Class	
GO:0140313	biolink:NamedThing	molecular sequestering activity	The selective interaction of a protein with a specific molecule to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	got7fsn_ti							pg	2019-03-28T10:00:25Z						molecular_function											owl:Class	
GO:0097068	biolink:NamedThing	response to thyroxine	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.	got7fsn_ti	response to thyroxine stimulus|response to T4 stimulus|response to T4						pr	2011-06-14T05:05:07Z						biological_process											owl:Class	
GO:0097066	biolink:NamedThing	response to thyroid hormone	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.	got7fsn_ti	response to thyroid hormone stimulus						pr	2011-06-14T05:01:18Z						biological_process											owl:Class	
GO:0021895	biolink:NamedThing	cerebral cortex neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0021953	biolink:NamedThing	central nervous system neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0003241	biolink:NamedThing	growth involved in heart morphogenesis	Developmental growth that contributes to the shaping of the heart.	got7fsn_ti							dph	2009-10-13T11:28:46Z						biological_process											owl:Class	
GO:0016402	biolink:NamedThing	pristanoyl-CoA oxidase activity	Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide.	got7fsn_ti												RHEA:40459|Reactome:R-HSA-389889|Reactome:R-HSA-389891		molecular_function											owl:Class	
GO:0003997	biolink:NamedThing	acyl-CoA oxidase activity	Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.	got7fsn_ti	fatty acyl-CoA oxidase activity|acyl-CoA:oxygen 2-oxidoreductase activity|fatty acyl-coenzyme A oxidase activity|acyl coenzyme A oxidase activity											RHEA:38959|EC:1.3.3.6|Reactome:R-HSA-193369|Reactome:R-HSA-390256|Reactome:R-HSA-2066787|Reactome:R-HSA-192335|MetaCyc:ACYL-COA-OXIDASE-RXN		molecular_function											owl:Class	
GO:0050988	biolink:NamedThing	N-terminal peptidyl-methionine carboxylation	The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine.	got7fsn_ti												RESID:AA0363		biological_process											owl:Class	
GO:0050989	biolink:NamedThing	N-terminal protein amino acid carboxylation	The carboxylation of the N-terminal amino acid of proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0051403	biolink:NamedThing	stress-activated MAPK cascade	A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase.	got7fsn_ti	MAPK14 cascade|MAPK12 cascade|stress-activated MAPKKK signalling pathway|p38 MAPK signaling|stress-activated MAPK signaling pathway|p38 cascade|p38 MAPK signalling|MAPK11 cascade|stress-activated MAPK signalling pathway|MAPK13 cascade|stress-activated MAPKKK signaling pathway|SAPK cascade|stress-activated MAPKKK cascade													biological_process											owl:Class	
GO:0031098	biolink:NamedThing	stress-activated protein kinase signaling cascade	A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.	got7fsn_ti	JNK signalling pathway|stress-activated protein kinase signaling pathway|stress-activated protein kinase signalling pathway|JNK signaling pathway|SAPK signalling pathway|SAPK signaling pathway													biological_process											owl:Class	
GO:0038086	biolink:NamedThing	VEGF-activated platelet-derived growth factor receptor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	VEGF-activated platelet-derived growth factor receptor signalling pathway|vascular endothelial growth factor-activated platelet-derived growth factor receptor signaling pathway|VEGF-activated PDGFR signalling pathway|VEGF/PDGFR signaling pathway|VEGF-A/PDGFR signaling						bf	2012-02-01T03:05:43Z						biological_process											owl:Class	
GO:0048008	biolink:NamedThing	platelet-derived growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.	got7fsn_ti	PDGFR signaling pathway|PDGF receptor signalling pathway|PDGF receptor signaling pathway													biological_process											owl:Class	
GO:0097226	biolink:NamedThing	sperm mitochondrial sheath	The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.	got7fsn_ti							pr	2012-01-25T01:25:08Z						cellular_component											owl:Class	
GO:0060735	biolink:NamedThing	regulation of eIF2 alpha phosphorylation by dsRNA	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.	got7fsn_ti	regulation of eIF2 alpha phosphorylation by double-stranded RNA|regulation of eIF2 alpha phosphorylation by PKR						dph	2009-06-12T02:27:14Z						biological_process											owl:Class	
GO:0001932	biolink:NamedThing	regulation of protein phosphorylation	Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.	got7fsn_ti	regulation of protein amino acid phosphorylation													biological_process											owl:Class	
GO:0050079	biolink:NamedThing	acetylenecarboxylate hydratase activity, producing 3-oxopropanoate	Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O.	got7fsn_ti	3-oxopropanoate hydro-lyase activity|acetylmonocarboxylic acid hydrase activity|acetylenecarboxylate hydratase activity|acetylenemonocarboxylate hydrase activity|acetylenemonocarboxylate hydratase activity|malonate-semialdehyde dehydratase activity|acetylenecarboxylate hydratase activity, producing malonate-semialdehyde|alkynoate hydratase activity|3-oxopropanoate hydro-lyase (propynoate-forming)				Note that this function was formerly EC:4.2.1.71.						GO:0047607	EC:4.2.1.27|MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN|RHEA:17957		molecular_function											owl:Class	
GO:0021601	biolink:NamedThing	abducens nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	got7fsn_ti	CN VI maturation													biological_process											owl:Class	
GO:0021605	biolink:NamedThing	cranial nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	got7fsn_ti														biological_process											owl:Class	
GO:0072683	biolink:NamedThing	T cell extravasation	The migration of a T cell from the blood vessels into the surrounding tissue.	got7fsn_ti	T lymphocyte extravasation|T-lymphocyte extravasation|T-cell extravasation						mah	2011-02-22T04:05:45Z						biological_process											owl:Class	
GO:0045123	biolink:NamedThing	cellular extravasation	The migration of a leukocyte from the blood vessels into the surrounding tissue.	got7fsn_ti	immune cell cellular extravasation|leucocyte cellular extravasation|transendothelial leukocyte migration|leukocyte cellular extravasation											Wikipedia:Leukocyte_extravasation		biological_process											owl:Class	
GO:0021700	biolink:NamedThing	developmental maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.	got7fsn_ti														biological_process											owl:Class	
GO:0048932	biolink:NamedThing	myelination of posterior lateral line nerve axons	The formation of compact myelin sheaths around the axons of the posterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0048897	biolink:NamedThing	myelination of lateral line nerve axons	The formation of compact myelin sheaths around the axons of a lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0061202	biolink:NamedThing	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.	got7fsn_ti	clathrin sculpted gamma-aminobutyric acid transport vesicle membrane|clathrin sculpted GABA transport vesicle membrane						dph	2010-07-29T10:54:33Z						cellular_component											owl:Class	
GO:0030665	biolink:NamedThing	clathrin-coated vesicle membrane	The lipid bilayer surrounding a clathrin-coated vesicle.	got7fsn_ti	clathrin coated vesicle membrane													cellular_component											owl:Class	
GO:0009718	biolink:NamedThing	anthocyanin-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.	got7fsn_ti	anthocyanin biosynthesis|anthocyanin biosynthetic process|anthocyanin synthesis|anthocyanin anabolism|anthocyanin formation													biological_process											owl:Class	
GO:0046148	biolink:NamedThing	pigment biosynthetic process	The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.	got7fsn_ti	pigment synthesis|pigment formation|pigment biosynthesis|pigment anabolism													biological_process											owl:Class	
GO:0007295	biolink:NamedThing	growth of a germarium-derived egg chamber	Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster.	got7fsn_ti	egg chamber growth													biological_process											owl:Class	
GO:0048589	biolink:NamedThing	developmental growth	The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.	got7fsn_ti														biological_process											owl:Class	
GO:0072205	biolink:NamedThing	metanephric collecting duct development	The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.	got7fsn_ti							mah	2010-03-18T11:15:37Z						biological_process											owl:Class	
GO:0072044	biolink:NamedThing	collecting duct development	The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.	got7fsn_ti							mah	2010-01-25T03:18:06Z						biological_process											owl:Class	
GO:0001700	biolink:NamedThing	embryonic development via the syncytial blastoderm	The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0009792	biolink:NamedThing	embryo development ending in birth or egg hatching	The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.	got7fsn_ti	embryogenesis													biological_process											owl:Class	
GO:0009267	biolink:NamedThing	cellular response to starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.	got7fsn_ti														biological_process											owl:Class	
GO:0042594	biolink:NamedThing	response to starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.	got7fsn_ti														biological_process											owl:Class	
GO:0014745	biolink:NamedThing	negative regulation of muscle adaptation	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.	got7fsn_ti	negative regulation of muscle plasticity													biological_process											owl:Class	
GO:0048585	biolink:NamedThing	negative regulation of response to stimulus	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.	got7fsn_ti	down-regulation of response to stimulus|inhibition of response to stimulus|downregulation of response to stimulus|down regulation of response to stimulus				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0047363	biolink:NamedThing	triglucosylalkylacylglycerol sulfotransferase activity	Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.	got7fsn_ti	triglucosylalkylacylglycerol sulphotransferase activity|3'-phosphoadenylyl-sulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase activity|triglucosylmonoalkylmonoacyl sulfotransferase activity											RHEA:13273|EC:2.8.2.19|MetaCyc:2.8.2.19-RXN		molecular_function											owl:Class	
GO:0042771	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis													biological_process											owl:Class	
GO:0072332	biolink:NamedThing	intrinsic apoptotic signaling pathway by p53 class mediator	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|signal transduction by p53 class mediator resulting in induction of apoptosis						mah	2010-11-03T01:47:56Z						biological_process											owl:Class	
GO:0140338	biolink:NamedThing	sphingomyelin transfer activity	Removes a sphingomyelin from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.	got7fsn_ti	sphingosine transmembrane transporter activity|sphingomyelin carrier activity						pg	2019-05-16T11:31:58Z			GO:0010175			molecular_function											owl:Class	
GO:0120013	biolink:NamedThing	lipid transfer activity	Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.	got7fsn_ti	lipid carrier activity|intermembrane lipid transfer activity	https://github.com/geneontology/go-ontology/issues/12329|https://github.com/geneontology/go-ontology/issues/17648					krc	2017-03-17T03:17:29Z						molecular_function											owl:Class	
GO:0004134	biolink:NamedThing	4-alpha-glucanotransferase activity	Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.	got7fsn_ti	D-enzyme activity|amylomaltase activity|oligo-1,4-1,4-glucantransferase activity|debranching enzyme maltodextrin glycosyltransferase activity|1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase activity|dextrin glycosyltransferase activity|disproportionating enzyme activity|dextrin transglycosylase activity											Reactome:R-HSA-71552|MetaCyc:RXN-1828|MetaCyc:RXN-9023|EC:2.4.1.25|MetaCyc:AMYLOMALT-RXN		molecular_function											owl:Class	
GO:0004133	biolink:NamedThing	glycogen debranching enzyme activity	Catalysis of the cleavage of branch points in branched glycogen polymers.	got7fsn_ti														molecular_function											owl:Class	
GO:0047747	biolink:NamedThing	cholate-CoA ligase activity	Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA.	got7fsn_ti	choloyl coenzyme A synthetase activity|cholate thiokinase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity|cholic thiokinase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity|BAL activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity|trihydroxycoprostanoyl-CoA synthetase activity|bile acid CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity|cholyl-CoA synthetase activity|cholate:CoA ligase (AMP-forming)|cholic acid:CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity|bile acid coenzyme A ligase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)|choloyl-CoA synthetase activity|THCA-CoA ligase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity										GO:0047477	EC:6.2.1.7|MetaCyc:CHOLATE--COA-LIGASE-RXN		molecular_function											owl:Class	
GO:0060134	biolink:NamedThing	prepulse inhibition	The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.	got7fsn_ti	pre-pulse inhibition|PPI											Wikipedia:Prepulse_inhibition		biological_process											owl:Class	
GO:0032102	biolink:NamedThing	negative regulation of response to external stimulus	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.	got7fsn_ti	inhibition of response to external stimulus|downregulation of response to external stimulus|down-regulation of response to external stimulus|down regulation of response to external stimulus				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0043354	biolink:NamedThing	enucleate erythrocyte maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.	got7fsn_ti	enucleate RBC maturation|enucleate red blood cell maturation													biological_process											owl:Class	
GO:0043249	biolink:NamedThing	erythrocyte maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state.	got7fsn_ti	red blood cell maturation|RBC maturation													biological_process											owl:Class	
GO:0050320	biolink:NamedThing	tartrate epimerase activity	Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate.	got7fsn_ti	tartaric racemase activity											KEGG_REACTION:R02546|EC:5.1.2.5|MetaCyc:TARTRATE-EPIMERASE-RXN|RHEA:22212		molecular_function											owl:Class	
GO:0106267	biolink:NamedThing	3,5 dichloro-THPH synthase activity	Catalysis of the reaction: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 = (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O.	got7fsn_ti							hjd	2020-06-02T18:16:23Z				RHEA:64360		molecular_function											owl:Class	
GO:0016712	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.	got7fsn_ti	flavoprotein-linked monooxygenase activity|cytochrome p450 activity|microsomal P-450|microsomal p450 activity|substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)|xenobiotic monooxygenase activity|unspecific monooxygenase activity|flavoprotein monooxygenase activity|microsomal monooxygenase activity|cytochrome P450 CYP19|aryl hydrocarbon hydroxylase activity|aryl-4-monooxygenase activity										GO:0008402|GO:0050381	Reactome:R-HSA-211966|UM-BBD_enzymeID:e0551|EC:1.14.14.-		molecular_function											owl:Class	
GO:0000331	biolink:NamedThing	contractile vacuole	A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory.	got7fsn_ti	central bladder|central vacuole											Wikipedia:Contractile_vacuole		cellular_component											owl:Class	
GO:0005773	biolink:NamedThing	vacuole	A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.	got7fsn_ti	vacuolar carboxypeptidase Y											Wikipedia:Vacuole		cellular_component											owl:Class	
GO:0070444	biolink:NamedThing	oligodendrocyte progenitor proliferation	The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.	got7fsn_ti	oligodendrocyte precursor proliferation													biological_process											owl:Class	
GO:0061351	biolink:NamedThing	neural precursor cell proliferation	The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.	got7fsn_ti							dph	2010-10-01T11:06:04Z						biological_process											owl:Class	
GO:0042296	biolink:NamedThing	ISG15 transferase activity	Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y --> Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages.	got7fsn_ti	ISG15 conjugating enzyme activity											Reactome:R-HSA-5653754		molecular_function											owl:Class	
GO:0019787	biolink:NamedThing	ubiquitin-like protein transferase activity	Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.	got7fsn_ti	small conjugating protein transferase activity|E3|small conjugating protein ligase activity|small protein conjugating enzyme activity|ubiquitin-like-protein ligase activity|ubiquitin-like conjugating enzyme activity|E2										GO:0008639|GO:0008640	Reactome:R-HSA-5678490|Reactome:R-HSA-688137		molecular_function											owl:Class	
GO:0030282	biolink:NamedThing	bone mineralization	The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.	got7fsn_ti	bone calcification													biological_process											owl:Class	
GO:0031214	biolink:NamedThing	biomineral tissue development	Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.	got7fsn_ti												Wikipedia:Biomineralization		biological_process											owl:Class	
GO:0034387	biolink:NamedThing	4-aminobutyrate:pyruvate transaminase activity	Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine.	got7fsn_ti	gamma-aminobutyric acid pyruvate transaminase activity											MetaCyc:RXN-6902|RHEA:32263|EC:2.6.1.96		molecular_function											owl:Class	
GO:0003867	biolink:NamedThing	4-aminobutyrate transaminase activity	Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid.	got7fsn_ti	beta-alanine aminotransferase|gamma-aminobutyric transaminase activity|aminobutyrate transaminase activity|GABA aminotransferase activity|GABA transferase activity|gamma-aminobutyric acid aminotransferase activity|glutamate-succinic semialdehyde transaminase activity|aminobutyrate aminotransferase activity|gamma-amino-N-butyrate transaminase activity|4-aminobutyrate aminotransferase activity|4-aminobutanoate transaminase activity|gamma-aminobutyrate transaminase activity|4-aminobutyric acid aminotransferase activity|gamma-aminobutyrate aminotransaminase activity|gamma-aminobutyric acid transaminase activity|GABA transaminase activity											RHEA:23352|Reactome:R-HSA-916855|MetaCyc:GABATRANSAM-RXN		molecular_function											owl:Class	
GO:0042165	biolink:NamedThing	neurotransmitter binding	Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.	got7fsn_ti														molecular_function											owl:Class	
GO:0005488	biolink:NamedThing	binding	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.	got7fsn_ti	ligand				Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.							Wikipedia:Binding_(molecular)		molecular_function											owl:Class	
GO:0050083	biolink:NamedThing	malyl-CoA lyase activity	Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.	got7fsn_ti	(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)|malyl-coenzyme A lyase activity|(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase activity											MetaCyc:MALYL-COA-LYASE-RXN|EC:4.1.3.24|RHEA:16629		molecular_function											owl:Class	
GO:0016833	biolink:NamedThing	oxo-acid-lyase activity	Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.	got7fsn_ti	oxo-acid lyase activity|oxoacid lyase activity											EC:4.1.3.-		molecular_function											owl:Class	
GO:0050290	biolink:NamedThing	sphingomyelin phosphodiesterase D activity	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide 1-phosphate + choline + H(+).	got7fsn_ti	sphingomyelinase D|sphingomyelin ceramide-phosphohydrolase activity											MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN|EC:3.1.4.41|RHEA:20984|KEGG_REACTION:R02542		molecular_function											owl:Class	
GO:0008081	biolink:NamedThing	phosphoric diester hydrolase activity	Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.	got7fsn_ti	phosphodiesterase										GO:0004434|GO:0016792	EC:3.1.4.-|Reactome:R-HSA-5693578		molecular_function											owl:Class	
GO:0002450	biolink:NamedThing	B cell antigen processing and presentation	The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	got7fsn_ti	B-cell antigen processing and presentation|B lymphocyte antigen processing and presentation|B-lymphocyte antigen processing and presentation													biological_process											owl:Class	
GO:1902761	biolink:NamedThing	positive regulation of chondrocyte development	Any process that activates or increases the frequency, rate or extent of chondrocyte development.	got7fsn_ti	upregulation of chondrocyte development|up regulation of chondrocyte development|up-regulation of chondrocyte development|activation of chondrocyte development						mr	2014-03-07T17:45:55Z						biological_process											owl:Class	
GO:0061181	biolink:NamedThing	regulation of chondrocyte development	Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.	got7fsn_ti							dph	2010-07-14T08:28:52Z						biological_process											owl:Class	
GO:0010476	biolink:NamedThing	gibberellin mediated signaling pathway	The series of molecular signals generated as a consequence of gibberellin stimulus.	got7fsn_ti	gibberellin-mediated signalling													biological_process											owl:Class	
GO:0009755	biolink:NamedThing	hormone-mediated signaling pathway	A series of molecular signals mediated by the detection of a hormone.	got7fsn_ti	hormone mediated signalling													biological_process											owl:Class	
GO:0010098	biolink:NamedThing	suspensor development	The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm.	got7fsn_ti														biological_process											owl:Class	
GO:0047837	biolink:NamedThing	D-xylose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH.	got7fsn_ti	D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|D-xylose:NADP+ 1-oxidoreductase activity|D-xylose:NADP+ oxidoreductase activity|D-xylose-NADP dehydrogenase activity											MetaCyc:D-XYLOSE-1-DEHYDROGENASE-NADP+-RXN|RHEA:22000|EC:1.1.1.179|KEGG_REACTION:R01430		molecular_function											owl:Class	
GO:0102931	biolink:NamedThing	(Z,E)-alpha- farnesene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8931		molecular_function											owl:Class	
GO:0014902	biolink:NamedThing	myotube differentiation	The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	got7fsn_ti														biological_process											owl:Class	
GO:0051146	biolink:NamedThing	striated muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.	got7fsn_ti	voluntary muscle cell differentiation													biological_process											owl:Class	
GO:0000702	biolink:NamedThing	oxidized base lesion DNA N-glycosylase activity	Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.	got7fsn_ti														molecular_function											owl:Class	
GO:0052880	biolink:NamedThing	oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein.	got7fsn_ti												EC:1.10.9.-		molecular_function											owl:Class	
GO:0016679	biolink:NamedThing	oxidoreductase activity, acting on diphenols and related substances as donors	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors											EC:1.10.-.-		molecular_function											owl:Class	
GO:1990692	biolink:NamedThing	trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane	The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.	got7fsn_ti	trans-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane						bhm	2015-03-12T09:54:02Z						biological_process											owl:Class	
GO:0048210	biolink:NamedThing	Golgi vesicle fusion to target membrane	The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.	got7fsn_ti	dictyosome vesicle fusion to target membrane|Golgi-derived vesicle fusion to target membrane													biological_process											owl:Class	
GO:0015638	biolink:NamedThing	microcin transmembrane transporter activity	Enables the transfer of a microcin from one side of a membrane to the other.	got7fsn_ti	microcin uptake permease activity													molecular_function											owl:Class	
GO:0042910	biolink:NamedThing	xenobiotic transmembrane transporter activity	Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	multidrug, alkane resistant pump activity|multidrug efflux pump activity|drug transmembrane transporter activity|drug transporter activity|multidrug transporter activity|xenobiotic transporter activity	https://github.com/geneontology/go-ontology/issues/19460									GO:0015559|GO:0015564|GO:0090484|GO:0015238|GO:0015239			molecular_function											owl:Class	
GO:0016641	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.	got7fsn_ti												EC:1.4.3.-		molecular_function											owl:Class	
GO:0016638	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors											EC:1.4.-.-		molecular_function											owl:Class	
GO:0016054	biolink:NamedThing	organic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.	got7fsn_ti	organic acid degradation|organic acid catabolism|organic acid breakdown													biological_process											owl:Class	
GO:0006082	biolink:NamedThing	organic acid metabolic process	The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.	got7fsn_ti	organic acid metabolism													biological_process											owl:Class	
GO:0070043	biolink:NamedThing	rRNA (guanine-N7-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.	got7fsn_ti												Reactome:R-HSA-6790982		molecular_function											owl:Class	
GO:1990834	biolink:NamedThing	response to odorant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.	got7fsn_ti							sl	2015-08-21T18:51:52Z						biological_process											owl:Class	
GO:0042221	biolink:NamedThing	response to chemical	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.	got7fsn_ti	response to chemical stimulus|response to chemical substance				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0005145	biolink:NamedThing	interleukin-14 receptor binding	Binding to an interleukin-14 receptor.	got7fsn_ti	IL-14|interleukin-14 receptor ligand													molecular_function											owl:Class	
GO:0021521	biolink:NamedThing	ventral spinal cord interneuron specification	The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.	got7fsn_ti														biological_process											owl:Class	
GO:0048665	biolink:NamedThing	neuron fate specification	The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0030588	biolink:NamedThing	pseudocleavage	Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis.	got7fsn_ti														biological_process											owl:Class	
GO:0038060	biolink:NamedThing	nitric oxide-cGMP-mediated signaling pathway	Any intracellular signal transduction in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP.	got7fsn_ti	canonical nitric oxide signaling|NO-cGMP signaling pathway|classical nitric oxide signaling|nitric oxide-cGMP-mediated signalling pathway						bf	2012-01-10T05:32:39Z						biological_process											owl:Class	
GO:0007263	biolink:NamedThing	nitric oxide mediated signal transduction	Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.	got7fsn_ti	nitric oxide-mediated signal transduction|NO-mediated signal transduction|nitric oxide signaling|NO mediated signal transduction													biological_process											owl:Class	
GO:0050594	biolink:NamedThing	tabersonine 16-hydroxylase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+).	got7fsn_ti	tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating)											MetaCyc:1.14.13.73-RXN|EC:1.14.14.103|KEGG_REACTION:R05855|RHEA:14133		molecular_function											owl:Class	
GO:0009418	biolink:NamedThing	pilus shaft	The long, slender, mid section of a pilus.	got7fsn_ti	fimbrial shaft													cellular_component											owl:Class	
GO:0021623	biolink:NamedThing	oculomotor nerve formation	The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	got7fsn_ti	CN III biosynthesis|CN III formation													biological_process											owl:Class	
GO:0021603	biolink:NamedThing	cranial nerve formation	The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	got7fsn_ti														biological_process											owl:Class	
GO:0003209	biolink:NamedThing	cardiac atrium morphogenesis	The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.	got7fsn_ti							dph	2009-10-13T09:39:44Z						biological_process											owl:Class	
GO:1990117	biolink:NamedThing	B cell receptor apoptotic signaling pathway	An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell.	got7fsn_ti	B cell receptor extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway via BCR|extrinsic apoptotic signaling pathway via B cell antigen receptor						pr	2013-06-06T15:15:17Z						biological_process											owl:Class	
GO:0035771	biolink:NamedThing	interleukin-4-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-4-mediated signalling pathway|IL-4-mediated signaling pathway						bf	2011-04-01T10:56:46Z						biological_process											owl:Class	
GO:0044809	biolink:NamedThing	chemokine (C-C motif) ligand 17 production	The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CCL17 production|thymus and activation regulated chemokine production|TARC production						jl	2013-09-11T12:21:31Z						biological_process											owl:Class	
GO:0032602	biolink:NamedThing	chemokine production	The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.	got7fsn_ti	chemokine synthesis|chemokine biosynthetic process|chemokine secretion|chemokine anabolism|chemokine formation|chemokine biosynthesis|chemokine metabolic process							2009-12-18T11:26:20Z			GO:0090195|GO:0042033|GO:0050755			biological_process											owl:Class	
GO:0036501	biolink:NamedThing	UFD1-NPL4 complex	A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p.	got7fsn_ti	Npl4p-Ufd1p complex|Ufd1/Npl4 complex|UFD1L-NPLOC4 complex|Ufd1-Npl4 cofactor complex|Ufd1-Npl4 binary complex						bf	2015-05-14T10:59:43Z						cellular_component											owl:Class	
GO:0071417	biolink:NamedThing	cellular response to organonitrogen compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.	got7fsn_ti	cellular response to organic nitrogen						mah	2009-12-14T04:07:27Z						biological_process											owl:Class	
GO:0071495	biolink:NamedThing	cellular response to endogenous stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-18T02:25:40Z						biological_process											owl:Class	
GO:0106017	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.	got7fsn_ti							hjd	2017-05-10T14:08:06Z						molecular_function											owl:Class	
GO:0034593	biolink:NamedThing	phosphatidylinositol bisphosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate.	got7fsn_ti	triphosphoinositide phosphomonoesterase activity|diphosphoinositide phosphatase activity|phosphatidylinositol-bisphosphatase activity|triphosphoinositide phosphatase activity|phosphatidyl-inositol-bisphosphate phosphatase activity													molecular_function											owl:Class	
GO:0046889	biolink:NamedThing	positive regulation of lipid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.	got7fsn_ti	up regulation of lipid biosynthetic process|positive regulation of lipogenesis|stimulation of lipid biosynthetic process|activation of lipid biosynthetic process|positive regulation of lipid synthesis|up-regulation of lipid biosynthetic process|positive regulation of lipid formation|positive regulation of lipid biosynthesis|upregulation of lipid biosynthetic process|positive regulation of lipid anabolism													biological_process											owl:Class	
GO:0046890	biolink:NamedThing	regulation of lipid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.	got7fsn_ti	regulation of lipid formation|regulation of lipogenesis|regulation of lipid biosynthesis|regulation of lipid synthesis|regulation of lipid anabolism													biological_process											owl:Class	
GO:0031434	biolink:NamedThing	mitogen-activated protein kinase kinase binding	Binding to a mitogen-activated protein kinase kinase, a protein that can phosphorylate a MAP kinase.	got7fsn_ti	MAPKK binding													molecular_function											owl:Class	
GO:0019901	biolink:NamedThing	protein kinase binding	Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.	got7fsn_ti														molecular_function											owl:Class	
GO:0022852	biolink:NamedThing	glycine-gated chloride ion channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0022824	biolink:NamedThing	transmitter-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	ionotropic neurotransmitter receptor activity													molecular_function											owl:Class	
GO:0010445	biolink:NamedThing	nuclear dicing body	A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes.	got7fsn_ti	D body													cellular_component											owl:Class	
GO:0016604	biolink:NamedThing	nuclear body	Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.	got7fsn_ti												NIF_Subcellular:sao505137457		cellular_component											owl:Class	
GO:0034554	biolink:NamedThing	3,3',5-tribromobisphenol A reductive dehalogenase activity	Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr.	got7fsn_ti												UM-BBD_reactionID:r0842|EC:1.97.1.-		molecular_function											owl:Class	
GO:1990864	biolink:NamedThing	response to growth hormone-releasing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins.	got7fsn_ti	response to sermorelin|response to somatoliberin|response to somatorelin|response to GHRF|response to GRF|response to somatocrinin|response to growth hormone-releasing factor						sl	2015-09-25T14:45:31Z						biological_process											owl:Class	
GO:0009163	biolink:NamedThing	nucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	got7fsn_ti	nucleoside formation|nucleoside synthesis|nucleoside biosynthesis|nucleoside anabolism													biological_process											owl:Class	
GO:0034404	biolink:NamedThing	nucleobase-containing small molecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.	got7fsn_ti	nucleobase, nucleoside and nucleotide formation|nucleobase, nucleoside and nucleotide biosynthesis|nucleobase, nucleoside and nucleotide anabolism|nucleobase, nucleoside and nucleotide synthesis													biological_process											owl:Class	
GO:0097435	biolink:NamedThing	supramolecular fiber organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.	got7fsn_ti	fibril organization|extracellular fibril organization|fibril organisation|extracellular fibril organization and biogenesis|extracellular fibril organisation						pr	2012-11-27T15:46:25Z			GO:0043206			biological_process											owl:Class	
GO:0016043	biolink:NamedThing	cellular component organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.	got7fsn_ti	cellular component organization at cellular level|cellular component organisation in other organism|cell organization and biogenesis|cellular component organisation at cellular level|cellular component organization in other organism|cell organisation										GO:0044235|GO:0071842			biological_process											owl:Class	
GO:0061521	biolink:NamedThing	hepatic stellate cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.	got7fsn_ti							dph	2013-04-18T13:36:08Z						biological_process											owl:Class	
GO:0018218	biolink:NamedThing	peptidyl-cysteine phosphorylation	The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine.	got7fsn_ti												RESID:AA0034		biological_process											owl:Class	
GO:1990315	biolink:NamedThing	Mcs4 RR-MAPKKK complex	A protein complex that consists of a phospho relay component and a MAPK cascade component.  The complex is involved in signaling oxidative stress and osmostress.	got7fsn_ti					In S. pombe it consists of Mpr1, Tdh1, Mcs4, Win1, Wis4 and Wis1.		al	2014-03-14T09:59:45Z						cellular_component											owl:Class	
GO:0099589	biolink:NamedThing	serotonin receptor activity	Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.	got7fsn_ti														molecular_function											owl:Class	
GO:0050740	biolink:NamedThing	protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine	The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine.	got7fsn_ti												RESID:AA0349		biological_process											owl:Class	
GO:0060407	biolink:NamedThing	negative regulation of penile erection	Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.	got7fsn_ti														biological_process											owl:Class	
GO:0015049	biolink:NamedThing	methane monooxygenase activity	Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O.	got7fsn_ti	methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)|methane hydroxylase activity											UM-BBD_enzymeID:e0007|KEGG_REACTION:R01143|MetaCyc:METHANE-MONOOXYGENASE-RXN|EC:1.14.13.25|KEGG_REACTION:R01142		molecular_function											owl:Class	
GO:0009727	biolink:NamedThing	detection of ethylene stimulus	The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of ethene stimulus|perception of ethylene stimulus|detection of ethene stimulus													biological_process											owl:Class	
GO:0009723	biolink:NamedThing	response to ethylene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.	got7fsn_ti	response to ethylene stimulus|response to ethene stimulus													biological_process											owl:Class	
GO:0036176	biolink:NamedThing	response to neutral pH	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti							bf	2012-03-29T01:38:00Z						biological_process											owl:Class	
GO:0046780	biolink:NamedThing	suppression by virus of host mRNA splicing	Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production.	got7fsn_ti	suppression by virus of host splicing factor activity|viral inhibition of host mRNA splicing|negative regulation by virus of host mRNA splicing|viral dispersion of host splicing factors										GO:0046781			biological_process											owl:Class	
GO:0033119	biolink:NamedThing	negative regulation of RNA splicing	Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.	got7fsn_ti														biological_process											owl:Class	
GO:0097478	biolink:NamedThing	leaflet of membrane bilayer	Any of the two layers of lipid molecules that constitute a membrane.	got7fsn_ti	membrane leaflet						pr	2013-05-07T14:24:37Z						cellular_component											owl:Class	
GO:0061303	biolink:NamedThing	cornea development in camera-type eye	The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.	got7fsn_ti							dph	2010-09-14T02:09:08Z						biological_process											owl:Class	
GO:0061150	biolink:NamedThing	renal system segmentation	The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.	got7fsn_ti	urinary tract segmentation						dph	2010-06-02T09:23:01Z						biological_process											owl:Class	
GO:0080173	biolink:NamedThing	male-female gamete recognition during double fertilization forming a zygote and endosperm	The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana.	got7fsn_ti	gamete recognition|male-female gamete recognition						dhl	2011-04-26T04:58:58Z						biological_process											owl:Class	
GO:0009988	biolink:NamedThing	cell-cell recognition	Cell recognition between cells. May involve the formation of specialized cell junctions.	got7fsn_ti														biological_process											owl:Class	
GO:0043849	biolink:NamedThing	Ras palmitoyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.	got7fsn_ti	Ras protein acyltransferase activity|DHHC cysteine-rich domain-containing protein ERF2|palmitoyltransferase ERF2|ERF2													molecular_function											owl:Class	
GO:0019706	biolink:NamedThing	protein-cysteine S-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].	got7fsn_ti	protein-cysteine S-palmitoleyltransferase activity											EC:2.3.1.225|RHEA:36683|Reactome:R-HSA-9647982|Reactome:R-HSA-5682084|Reactome:R-HSA-9021072		molecular_function											owl:Class	
GO:0018096	biolink:NamedThing	peptide cross-linking via S-(2-aminovinyl)-D-cysteine	The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine.	got7fsn_ti												RESID:AA0204		biological_process											owl:Class	
GO:0045196	biolink:NamedThing	establishment or maintenance of neuroblast polarity	Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.	got7fsn_ti	establishment and/or maintenance of neuroblast cell polarity										GO:0043342|GO:0043339			biological_process											owl:Class	
GO:0007163	biolink:NamedThing	establishment or maintenance of cell polarity	Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.	got7fsn_ti	cell polarity|establishment and/or maintenance of cell polarity|establishment and/or maintenance of cell polarization										GO:0030467|GO:0030012			biological_process											owl:Class	
GO:0035907	biolink:NamedThing	dorsal aorta development	The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.	got7fsn_ti							bf	2011-06-24T11:07:01Z						biological_process											owl:Class	
GO:0035904	biolink:NamedThing	aorta development	The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.	got7fsn_ti							bf	2011-06-24T11:00:07Z						biological_process											owl:Class	
GO:0003858	biolink:NamedThing	3-hydroxybutyrate dehydrogenase activity	Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH.	got7fsn_ti	D-beta-hydroxybutyrate dehydrogenase activity											MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|EC:1.1.1.30|KEGG_REACTION:R01361|Reactome:R-HSA-73920|Reactome:R-HSA-73912|Reactome:R-HSA-5696457|RHEA:20521		molecular_function											owl:Class	
GO:0051337	biolink:NamedThing	amitosis	Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation.	got7fsn_ti	Remak nuclear division|direct nuclear division													biological_process											owl:Class	
GO:0000280	biolink:NamedThing	nuclear division	The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.	got7fsn_ti	karyokinesis													biological_process											owl:Class	
GO:0007377	biolink:NamedThing	germ-band extension	Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further.	got7fsn_ti														biological_process											owl:Class	
GO:0048598	biolink:NamedThing	embryonic morphogenesis	The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.	got7fsn_ti	embryonic anatomical structure morphogenesis										GO:0048828			biological_process											owl:Class	
GO:2000195	biolink:NamedThing	negative regulation of female gonad development	Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.	got7fsn_ti	negative regulation of ovary development|negative regulation of ovarian development						yaf	2010-10-19T10:45:38Z						biological_process											owl:Class	
GO:0051093	biolink:NamedThing	negative regulation of developmental process	Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	got7fsn_ti	downregulation of developmental process|inhibition of developmental process|down regulation of developmental process|down-regulation of developmental process													biological_process											owl:Class	
GO:0060472	biolink:NamedThing	positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration	Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.	got7fsn_ti	positive regulation of cortical granule exocytosis by elevation of cytosolic calcium ion concentration													biological_process											owl:Class	
GO:0045956	biolink:NamedThing	positive regulation of calcium ion-dependent exocytosis	Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis.	got7fsn_ti	up regulation of calcium ion-dependent exocytosis|activation of calcium ion-dependent exocytosis|up-regulation of calcium ion-dependent exocytosis|upregulation of calcium ion-dependent exocytosis|stimulation of calcium ion-dependent exocytosis													biological_process											owl:Class	
GO:0031803	biolink:NamedThing	type 6 metabotropic glutamate receptor binding	Binding to a type 6 metabotropic glutamate receptor.	got7fsn_ti	type 6 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0035256	biolink:NamedThing	G protein-coupled glutamate receptor binding	Binding to a G protein-coupled glutamate receptor (a metabotropic glutamate receptor).	got7fsn_ti	metabotropic glutamate receptor binding|G-protein coupled glutamate receptor binding													molecular_function											owl:Class	
GO:0102063	biolink:NamedThing	beta-curcumene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (-)-beta-curcumene.	got7fsn_ti												MetaCyc:RXN-10598		molecular_function											owl:Class	
GO:0003417	biolink:NamedThing	growth plate cartilage development	The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.	got7fsn_ti							dph	2009-12-22T08:57:42Z						biological_process											owl:Class	
GO:0060351	biolink:NamedThing	cartilage development involved in endochondral bone morphogenesis	The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.	got7fsn_ti														biological_process											owl:Class	
GO:0035888	biolink:NamedThing	isoguanine deaminase activity	Catalysis of the reaction: isoguanine + H2O = xanthine + NH3.	got7fsn_ti	2-oxoadenine deaminase activity|2-hydroxyadenine deaminase activity						bf	2011-06-14T02:15:53Z						molecular_function											owl:Class	
GO:1901991	biolink:NamedThing	negative regulation of mitotic cell cycle phase transition	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.	got7fsn_ti	downregulation of mitotic cell cycle phase transition|inhibition of mitotic cell cycle phase transition|down regulation of mitotic cell cycle phase transition|down-regulation of mitotic cell cycle phase transition						jl	2013-03-19T16:14:46Z						biological_process											owl:Class	
GO:0098622	biolink:NamedThing	selenodiglutathione-disulfide reductase activity	Catalysis of the reaction: H+ + selenodiglutathione + NADPH => gluthathioselenol + glutathione + NADP+.	got7fsn_ti												RHEA:34927|Reactome:R-HSA-2408542		molecular_function											owl:Class	
GO:0015036	biolink:NamedThing	disulfide oxidoreductase activity	Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.	got7fsn_ti	disulphide oxidoreductase activity											Reactome:R-HSA-1222417|Reactome:R-HSA-1222644|Reactome:R-HSA-264997|Reactome:R-HSA-1222690|Reactome:R-HSA-1222655		molecular_function											owl:Class	
GO:0071278	biolink:NamedThing	cellular response to cesium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.	got7fsn_ti	cellular response to cesium						mah	2009-12-10T03:55:44Z						biological_process											owl:Class	
GO:0010164	biolink:NamedThing	response to cesium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.	got7fsn_ti	response to cesium													biological_process											owl:Class	
GO:0014001	biolink:NamedThing	sclerenchyma cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable.	got7fsn_ti														biological_process											owl:Class	
GO:0052104	biolink:NamedThing	induction by symbiont of host systemic acquired resistance	Any process in which a symbiont activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of SAR in host|induction by organism of systemic acquired resistance in other organism involved in symbiotic interaction|activation by organism of systemic acquired resistance in host|up regulation by symbiont of systemic acquired resistance in host|positive regulation by symbiont of systemic acquired resistance in host|upregulation by symbiont of systemic acquired resistance in host|positive regulation by symbiont of host systemic acquired resistance|induction by symbiont of systemic acquired resistance in host|stimulation by symbiont of systemic acquired resistance in host|up-regulation by symbiont of systemic acquired resistance in host|positive regulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction|induction by organism of SAR in host										GO:0052535|GO:0052537|GO:0052289			biological_process											owl:Class	
GO:0052160	biolink:NamedThing	modulation by symbiont of host systemic acquired resistance	Any process in which a symbiont modulates the frequency, rate or extent of systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction|modulation by symbiont of systemic acquired resistance in host										GO:0052299			biological_process											owl:Class	
GO:0019799	biolink:NamedThing	tubulin N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine.	got7fsn_ti	acetyl-CoA:alpha-tubulin-L-lysine N6-acetyltransferase activity|alpha-tubulin acetyltransferase activity|alpha-tubulin N-acetyltransferase activity|alpha-tubulin acetylase activity|acetyl-CoA:alpha-tubulin-lysine N-acetyltransferase activity|TAT activity|tubulin acetyltransferase activity|acetyl-CoA:alpha-tubulin-L-lysine 6-N-acetyltransferase activity											MetaCyc:TUBULIN-N-ACETYLTRANSFERASE-RXN|RHEA:15277|EC:2.3.1.108		molecular_function											owl:Class	
GO:0061733	biolink:NamedThing	peptide-lysine-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.	got7fsn_ti							dph	2015-09-10T10:22:19Z				Reactome:R-HSA-9620515|Reactome:R-HSA-9617758|Reactome:R-HSA-9626945|Reactome:R-HSA-8951966|Reactome:R-HSA-6811508		molecular_function											owl:Class	
GO:0070078	biolink:NamedThing	histone H3-R2 demethylation	The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone.	got7fsn_ti														biological_process											owl:Class	
GO:0070077	biolink:NamedThing	histone arginine demethylation	The modification of a histone by the removal of a methyl group from an arginine residue.	got7fsn_ti														biological_process											owl:Class	
GO:0045184	biolink:NamedThing	establishment of protein localization	The directed movement of a protein to a specific location.	got7fsn_ti	establishment of protein localisation|protein recruitment|protein positioning													biological_process											owl:Class	
GO:0051234	biolink:NamedThing	establishment of localization	Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.	got7fsn_ti	establishment of localisation													biological_process											owl:Class	
GO:0022871	biolink:NamedThing	protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	sorbose PTS transporter activity	https://github.com/geneontology/go-ontology/issues/17289										EC:2.7.1.206|RHEA:49296		molecular_function											owl:Class	
GO:0019194	biolink:NamedThing	sorbose transmembrane transporter activity	Enables the transfer of sorbose from one side of a membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.	got7fsn_ti	sorbose porter activity										GO:0019193			molecular_function											owl:Class	
GO:0071357	biolink:NamedThing	cellular response to type I interferon	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	cellular response to type I IFN						mah	2009-12-11T02:51:47Z						biological_process											owl:Class	
GO:0034340	biolink:NamedThing	response to type I interferon	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	response to type I IFN													biological_process											owl:Class	
GO:0102169	biolink:NamedThing	pyocyanin hydroxylase activity	Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ <=> pyocyanin + NAD + carbon dioxide + H2O.	got7fsn_ti												MetaCyc:RXN-11898|RHEA:48976		molecular_function											owl:Class	
GO:0052249	biolink:NamedThing	modulation of RNA levels in other organism involved in symbiotic interaction	The alteration by an organism of the levels of RNA in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation of RNA levels in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0051817	biolink:NamedThing	modulation of process of other organism involved in symbiotic interaction	The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	regulation of physiology of other organism during symbiotic interaction|regulation of morphology of other organism during symbiotic interaction|modification of morphology or physiology of other organism involved in symbiotic interaction|regulation of physiological process in other organism during symbiotic interaction|modulation of morphology or physiology of other organism during symbiotic interaction|regulation of morphology or physiology of other organism during symbiotic interaction|modification of morphology or physiology of other organism during symbiotic interaction|modulation of biological process of other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18605												biological_process											owl:Class	
GO:0051660	biolink:NamedThing	establishment of centrosome localization	The directed movement of the centrosome to a specific location.	got7fsn_ti	establishment of centrosome localisation|centrosome positioning													biological_process											owl:Class	
GO:0051649	biolink:NamedThing	establishment of localization in cell	Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.	got7fsn_ti	establishment of intracellular localization|positioning within cell|establishment of localization within cell|establishment of localisation in cell|establishment of cellular localization													biological_process											owl:Class	
GO:0033763	biolink:NamedThing	proline 3-hydroxylase activity	Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.	got7fsn_ti	P-3-H|L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity											RHEA:20265|EC:1.14.11.28|MetaCyc:1.14.11.28-RXN		molecular_function											owl:Class	
GO:0018650	biolink:NamedThing	styrene monooxygenase activity	Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide.	got7fsn_ti												UM-BBD_reactionID:r0225|EC:1.14.13.-		molecular_function											owl:Class	
GO:0005360	biolink:NamedThing	insulin-responsive glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	got7fsn_ti	insulin-responsive hydrogen:glucose transporter activity|transepithelial hydrogen/glucose transporter activity|insulin-responsive hydrogen:glucose symporter activity													molecular_function											owl:Class	
GO:0005356	biolink:NamedThing	glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	got7fsn_ti	hydrogen:glucose transporter activity|transepithelial hydrogen:glucose symporter activity|transepithelial hydrogen:glucose transporter activity|hydrogen:glucose symporter activity|transepithelial hydrogen/glucose transporter activity										GO:0005361			molecular_function											owl:Class	
GO:0021564	biolink:NamedThing	vagus nerve development	The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	got7fsn_ti	cranial nerve X development|cranial nerve 10 development|CN X development													biological_process											owl:Class	
GO:0021545	biolink:NamedThing	cranial nerve development	The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	got7fsn_ti														biological_process											owl:Class	
GO:1990571	biolink:NamedThing	meiotic centromere clustering	The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I.	got7fsn_ti	centromere clustering during meiosis|homologous chromosome movement towards spindle pole in meiosis I prometaphase						mah	2014-12-02T11:25:37Z						biological_process											owl:Class	
GO:0016344	biolink:NamedThing	meiotic chromosome movement towards spindle pole	The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis.	got7fsn_ti	chromosome movement towards spindle pole during meiosis|meiotic chromosome movement|chromosome migration to spindle pole during meiosis|meiotic chromosome movement to spindle pole													biological_process											owl:Class	
GO:2000945	biolink:NamedThing	regulation of amylopectin catabolic process	Any process that modulates the frequency, rate or extent of amylopectin catabolic process.	got7fsn_ti	regulation of Amylopectin catabolism						tt	2011-08-01T02:15:22Z						biological_process											owl:Class	
GO:0031329	biolink:NamedThing	regulation of cellular catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.	got7fsn_ti	regulation of cellular degradation|regulation of cellular catabolism|regulation of cellular breakdown													biological_process											owl:Class	
GO:0007157	biolink:NamedThing	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.	got7fsn_ti	agglutination													biological_process											owl:Class	
GO:0051994	biolink:NamedThing	P-methyltransferase activity	Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule.	got7fsn_ti							ai	2010-07-16T04:39:34Z				EC:2.1.1.-		molecular_function											owl:Class	
GO:0030289	biolink:NamedThing	protein phosphatase 4 complex	A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.	got7fsn_ti														cellular_component											owl:Class	
GO:0007527	biolink:NamedThing	adult somatic muscle development	The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0007525	biolink:NamedThing	somatic muscle development	The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.	got7fsn_ti														biological_process											owl:Class	
GO:0030410	biolink:NamedThing	nicotianamine synthase activity	Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H(+) + nicotianamine.	got7fsn_ti	S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase activity											EC:2.5.1.43|KEGG_REACTION:R00075|MetaCyc:2.5.1.43-RXN|RHEA:16481		molecular_function											owl:Class	
GO:0047220	biolink:NamedThing	galactosylxylosylprotein 3-beta-galactosyltransferase activity	Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP.	got7fsn_ti	galactosyltransferase II activity|uridine diphosphogalactose-galactosylxylose galactosyltransferase activity|UDPgalactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity|UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity											RHEA:11780|Reactome:R-HSA-1889978|MetaCyc:2.4.1.134-RXN|Reactome:R-HSA-4420365|EC:2.4.1.134		molecular_function											owl:Class	
GO:0043844	biolink:NamedThing	ADP-specific phosphofructokinase activity	Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate.	got7fsn_ti	ADP:D-fructose-6-phosphate 1-phosphotransferase activity|ADP-dependent phosphofructokinase activity|ADP-6-phosphofructokinase activity|ADP-Pfk activity											EC:2.7.1.146|RHEA:20105		molecular_function											owl:Class	
GO:0016773	biolink:NamedThing	phosphotransferase activity, alcohol group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).	got7fsn_ti												Reactome:R-HSA-2161193|EC:2.7.1.-		molecular_function											owl:Class	
GO:0102447	biolink:NamedThing	rhamnetin 3'-O-methyltransferase activity	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine  <=> 7,3'-dimethylquercetin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-13933		molecular_function											owl:Class	
GO:0070941	biolink:NamedThing	eisosome assembly	The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane.	got7fsn_ti							mah	2009-09-30T02:49:30Z						biological_process											owl:Class	
GO:0022607	biolink:NamedThing	cellular component assembly	The aggregation, arrangement and bonding together of a cellular component.	got7fsn_ti	cellular component assembly at cellular level|cell structure assembly										GO:0071844			biological_process											owl:Class	
GO:0002477	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class Ib	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	got7fsn_ti	exogenous peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0002478	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.	got7fsn_ti	exogenous peptide antigen processing and presentation													biological_process											owl:Class	
GO:0016925	biolink:NamedThing	protein sumoylation	The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.	got7fsn_ti	Smt3-protein conjugation|small ubiquitin-related protein 1 conjugation|protein sumolation|SUMO-protein conjugation|sumoylation|Smt3p-protein conjugation										GO:0016927|GO:0006485|GO:0019951|GO:0019947	Wikipedia:SUMO_protein		biological_process											owl:Class	
GO:0032446	biolink:NamedThing	protein modification by small protein conjugation	A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.	got7fsn_ti														biological_process											owl:Class	
GO:0061541	biolink:NamedThing	rhabdomere morphogenesis	The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.	got7fsn_ti							dph	2013-06-24T07:59:25Z						biological_process											owl:Class	
GO:0048812	biolink:NamedThing	neuron projection morphogenesis	The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.	got7fsn_ti	neurite formation|neurite morphogenesis|neurite growth|neurite biosynthesis													biological_process											owl:Class	
GO:0044753	biolink:NamedThing	amphisome	Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes.	got7fsn_ti							jl	2012-11-27T15:35:25Z						cellular_component											owl:Class	
GO:0005776	biolink:NamedThing	autophagosome	A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.	got7fsn_ti	initial autophagic vacuole|autophagic vacuole											NIF_Subcellular:sao8663416959		cellular_component											owl:Class	
GO:0042404	biolink:NamedThing	thyroid hormone catabolic process	The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.	got7fsn_ti	thyroid hormone breakdown|thyroid hormone catabolism|thyroid hormone degradation													biological_process											owl:Class	
GO:0042219	biolink:NamedThing	cellular modified amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.	got7fsn_ti	cellular amino acid derivative catabolism|cellular modified amino acid breakdown|cellular amino acid derivative degradation|cellular modified amino acid catabolism|cellular modified amino acid degradation|modified amino acid catabolic process|cellular amino acid derivative catabolic process|amino acid derivative catabolic process|modified amino acid catabolism|cellular amino acid derivative breakdown													biological_process											owl:Class	
GO:0060920	biolink:NamedThing	cardiac pacemaker cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.	got7fsn_ti	pacemaker cell differentiation						dph	2009-09-29T11:01:31Z						biological_process											owl:Class	
GO:0055007	biolink:NamedThing	cardiac muscle cell differentiation	The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	got7fsn_ti	cardiomyocyte differentiation|heart muscle cell differentiation													biological_process											owl:Class	
GO:0009626	biolink:NamedThing	plant-type hypersensitive response	The rapid, localized death of plant cells in response to invasion by a pathogen.	got7fsn_ti	plant hypersensitive response|HR-PCD|HR				Note that term is to be used to annotate gene products in the plant. To annotate symbiont gene products that induce the hypersensitive response, consider the biological process term 'modulation by symbiont of host defense-related programmed cell death ; GO:0034053'.									biological_process											owl:Class	
GO:0052848	biolink:NamedThing	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	Catalysis of the reaction: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + H+.	got7fsn_ti							ai	2011-12-05T11:02:23Z				MetaCyc:RXN-10976		molecular_function											owl:Class	
GO:0052841	biolink:NamedThing	inositol bisdiphosphate tetrakisphosphate diphosphatase activity	Catalysis of the reaction: inositol bisdiphosphate tetrakisphosphate + H2O = inositol diphosphate pentakisphosphate + phosphate.	got7fsn_ti							ai	2011-11-29T04:14:22Z				Reactome:R-HSA-1855165|Reactome:R-HSA-2023973		molecular_function											owl:Class	
GO:0038137	biolink:NamedThing	ERBB4-EGFR signaling pathway	A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	HER1-HER4 signaling pathway|ERBB1-ERBB4 signaling pathway|ERBB4-EGFR signalling pathway						bf	2012-03-30T11:30:30Z						biological_process											owl:Class	
GO:0007173	biolink:NamedThing	epidermal growth factor receptor signaling pathway	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	ERBB1 signaling pathway|EGF receptor signalling pathway|EGF receptor signaling pathway|EGFR signaling pathway|receptor tyrosine-protein kinase erbB-1 signaling pathway|epidermal growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0090032	biolink:NamedThing	negative regulation of steroid hormone biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.	got7fsn_ti							tb	2009-08-03T10:41:35Z						biological_process											owl:Class	
GO:0032353	biolink:NamedThing	negative regulation of hormone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.	got7fsn_ti	down regulation of hormone biosynthetic process|downregulation of hormone biosynthetic process|inhibition of hormone biosynthetic process|down-regulation of hormone biosynthetic process													biological_process											owl:Class	
GO:0102879	biolink:NamedThing	(+)-thujopsene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-thujopsene + diphosphoric acid.	got7fsn_ti												RHEA:30375|EC:4.2.3.79|MetaCyc:RXN-8418		molecular_function											owl:Class	
GO:0060436	biolink:NamedThing	bronchiole morphogenesis	The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.	got7fsn_ti														biological_process											owl:Class	
GO:0033749	biolink:NamedThing	histone H3-methyl-arginine-3 demethylase activity	Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone demethylase activity (H4-R3 specific)|histone H3R3me demethylase activity	https://github.com/geneontology/go-ontology/issues/21089												molecular_function											owl:Class	
GO:0032452	biolink:NamedThing	histone demethylase activity	Catalysis of the removal of a methyl group from a histone.	got7fsn_ti												Reactome:R-HSA-5661116|Reactome:R-HSA-5661114|Reactome:R-HSA-5661125|Reactome:R-HSA-5625797|Reactome:R-HSA-5661120|Reactome:R-HSA-5661115|Reactome:R-HSA-4722133|Reactome:R-HSA-3214912|Reactome:R-HSA-5661121|Reactome:R-HSA-5661124|Reactome:R-HSA-5661122|Reactome:R-HSA-4724279|Reactome:R-HSA-4754187|Reactome:R-HSA-4754181|Reactome:R-HSA-5625848|Reactome:R-HSA-4724284|Reactome:R-HSA-5625870|Reactome:R-HSA-5423117|Reactome:R-HSA-5661123|Reactome:R-HSA-4754176		molecular_function											owl:Class	
GO:0023059	biolink:NamedThing	positive adaptation of signaling pathway	The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.	got7fsn_ti	positive adaptation of signalling pathway							2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0075039	biolink:NamedThing	establishment of turgor in appressorium	The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	generation of turgor in appressorium|formation of turgor in appressorium|establishment of turgor in symbiont appressorium on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0044111	biolink:NamedThing	formation of structure involved in a symbiotic process	The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.	got7fsn_ti	development of symbiont during interaction with host|development involved in symbiotic interaction|development during symbiotic interaction|development on or near surface of other organism during symbiotic interaction|development of symbiont involved in interaction with host|development on or near surface of other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/20305					jl	2009-07-30T02:26:46Z			GO:0044152|GO:0044115			biological_process											owl:Class	
GO:0045776	biolink:NamedThing	negative regulation of blood pressure	Any process in which the force of blood traveling through the circulatory system is decreased.	got7fsn_ti	down regulation of blood pressure|downregulation of blood pressure|inhibition of blood pressure|down-regulation of blood pressure													biological_process											owl:Class	
GO:0047800	biolink:NamedThing	cysteamine dioxygenase activity	Catalysis of the reaction: cysteamine + O(2) = H(+) + hypotaurine.	got7fsn_ti	cysteamine oxygenase activity|persulfurase activity|cysteamine:oxygen oxidoreductase activity|2-aminoethanethiol:oxygen oxidoreductase activity											EC:1.13.11.19|RHEA:14409|Reactome:R-HSA-6814153|MetaCyc:CYSTEAMINE-DIOXYGENASE-RXN|KEGG_REACTION:R02467		molecular_function											owl:Class	
GO:0016461	biolink:NamedThing	unconventional myosin complex	A portmanteau term for myosins other than myosin II.	got7fsn_ti	non-muscle myosin				Note that this term is retained because it is widely used by biologists.						GO:0005860			cellular_component											owl:Class	
GO:0016459	biolink:NamedThing	myosin complex	A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.	got7fsn_ti														cellular_component											owl:Class	
GO:0036265	biolink:NamedThing	RNA (guanine-N7)-methylation	The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.	got7fsn_ti							bf	2012-06-25T10:28:25Z						biological_process											owl:Class	
GO:0001510	biolink:NamedThing	RNA methylation	Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.	got7fsn_ti														biological_process											owl:Class	
GO:0070001	biolink:NamedThing	aspartic-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.	got7fsn_ti														molecular_function											owl:Class	
GO:0008233	biolink:NamedThing	peptidase activity	Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.	got7fsn_ti	protease activity|peptidase activity, acting on L-amino acid peptides|peptidase activity, acting on D-amino acid peptides|proteinase activity|peptide hydrolase activity|hydrolase, acting on peptide bonds										GO:0070010|GO:0070011	Reactome:R-HSA-5685902|EC:3.4.-.-|Reactome:R-HSA-5655483|Reactome:R-HSA-376149|Reactome:R-HSA-3065959|Reactome:R-HSA-3139027|Reactome:R-HSA-205112|Reactome:R-HSA-3065958|Reactome:R-HSA-6803060|Reactome:R-HSA-3000243|Reactome:R-HSA-4167501|Reactome:R-HSA-5693319|Reactome:R-HSA-448678|Reactome:R-HSA-5684864		molecular_function											owl:Class	
GO:0016059	biolink:NamedThing	deactivation of rhodopsin mediated signaling	The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).	got7fsn_ti	rod response recovery|deactivation of rhodopsin mediated signalling													biological_process											owl:Class	
GO:0022400	biolink:NamedThing	regulation of rhodopsin mediated signaling pathway	Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.	got7fsn_ti	regulation of rhodopsin mediated signalling													biological_process											owl:Class	
GO:0018554	biolink:NamedThing	1,2-dihydroxynaphthalene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached.	got7fsn_ti												UM-BBD_enzymeID:e0255|RHEA:27310|EC:1.13.11.56		molecular_function											owl:Class	
GO:0060805	biolink:NamedThing	negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter	Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast.	got7fsn_ti							dph	2009-08-06T01:58:25Z						biological_process											owl:Class	
GO:0060806	biolink:NamedThing	negative regulation of cell differentiation involved in embryonic placenta development	Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.	got7fsn_ti							dph	2009-08-06T02:02:18Z						biological_process											owl:Class	
GO:0003916	biolink:NamedThing	DNA topoisomerase activity	Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.	got7fsn_ti											GO:0009387	EC:5.6.2.-		molecular_function											owl:Class	
GO:0047123	biolink:NamedThing	quinoline-4-carboxylate 2-oxidoreductase activity	Catalysis of the reaction: A + H(2)O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2).	got7fsn_ti	quinoline-4-carboxylic acid 2-oxidoreductase activity|quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating)											KEGG_REACTION:R05183|RHEA:14949|EC:1.3.99.19|MetaCyc:1.3.99.19-RXN		molecular_function											owl:Class	
GO:0016627	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on the CH-CH group of donors, other acceptors											EC:1.3.-.-|Reactome:R-HSA-2995334|Reactome:R-HSA-9661710		molecular_function											owl:Class	
GO:0003859	biolink:NamedThing	3-hydroxybutyryl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H(2)O.	got7fsn_ti	enoyl coenzyme A hydrase (D)|crotonase activity|D-3-hydroxybutyryl-CoA dehydratase activity|(3R)-3-hydroxybutanoyl-CoA hydro-lyase activity|(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)|D-3-hydroxybutyryl coenzyme A dehydratase activity											RHEA:17849|KEGG_REACTION:R03027|MetaCyc:3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN|EC:4.2.1.55		molecular_function											owl:Class	
GO:0018106	biolink:NamedThing	peptidyl-histidine phosphorylation	The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).	got7fsn_ti												RESID:AA0036|RESID:AA0035		biological_process											owl:Class	
GO:0018202	biolink:NamedThing	peptidyl-histidine modification	The modification of peptidyl-histidine.	got7fsn_ti														biological_process											owl:Class	
GO:0005610	biolink:NamedThing	laminin-5 complex	A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains.	got7fsn_ti	laminin-3A32 complex|laminin-332 complex|laminin-5A complex													cellular_component											owl:Class	
GO:0023024	biolink:NamedThing	MHC class I protein complex binding	Binding to a class I major histocompatibility complex.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0023023	biolink:NamedThing	MHC protein complex binding	Binding to a major histocompatibility complex.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0055115	biolink:NamedThing	entry into diapause	The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.	got7fsn_ti												Wikipedia:Diapause		biological_process											owl:Class	
GO:0008966	biolink:NamedThing	phosphoglucosamine mutase activity	Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.	got7fsn_ti	D-glucosamine 1,6-phosphomutase activity|alpha-D-glucosamine 1,6-phosphomutase activity											MetaCyc:5.4.2.10-RXN|RHEA:23424|EC:5.4.2.10|KEGG_REACTION:R02060		molecular_function											owl:Class	
GO:0016868	biolink:NamedThing	intramolecular transferase activity, phosphotransferases	Catalysis of the transfer of a phosphate group from one position to another within a single molecule.	got7fsn_ti	phosphotransferase activity, with regeneration of donors, apparently catalyzing intramolecular transfers|phosphomutase activity										GO:0016777	EC:5.4.2.-		molecular_function											owl:Class	
GO:0102626	biolink:NamedThing	parthenolide synthase activity	Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> parthenolide + NADP(3-) + H2O.	got7fsn_ti												MetaCyc:RXN-15531		molecular_function											owl:Class	
GO:0010101	biolink:NamedThing	post-embryonic root morphogenesis	The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed.	got7fsn_ti														biological_process											owl:Class	
GO:0045766	biolink:NamedThing	positive regulation of angiogenesis	Any process that activates or increases angiogenesis.	got7fsn_ti	up-regulation of angiogenesis|activation of angiogenesis|stimulation of angiogenesis|up regulation of angiogenesis|upregulation of angiogenesis													biological_process											owl:Class	
GO:1904018	biolink:NamedThing	positive regulation of vasculature development	Any process that activates or increases the frequency, rate or extent of vasculature development.	got7fsn_ti	up regulation of vasculature development|positive regulation of vascular system development|up-regulation of vascular system development|upregulation of vascular system development|up regulation of vascular system development|upregulation of vasculature development|activation of vascular system development|activation of vasculature development|up-regulation of vasculature development						sl	2015-03-06T22:17:04Z						biological_process											owl:Class	
GO:0039688	biolink:NamedThing	viral double stranded DNA replication via reverse transcription	A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.	got7fsn_ti	RNA-dependent viral DNA replication|dsDNA replication via RNA intermediate|viral RNA-dependent DNA replication						bf	2013-10-17T15:00:08Z				VZ:1938		biological_process											owl:Class	
GO:0039693	biolink:NamedThing	viral DNA genome replication	The replication of a viral DNA genome.	got7fsn_ti	DNA-dependent viral DNA replication|viral DNA-dependent DNA replication|viral DNA replication						bf	2013-10-23T15:22:31Z			GO:0039681			biological_process											owl:Class	
GO:0009900	biolink:NamedThing	dehiscence	The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.	got7fsn_ti												Wikipedia:Dehiscence_(botany)		biological_process											owl:Class	
GO:0022414	biolink:NamedThing	reproductive process	A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.	got7fsn_ti	single organism reproductive process						jl	2012-09-19T15:56:06Z			GO:0044702			biological_process											owl:Class	
GO:0036503	biolink:NamedThing	ERAD pathway	The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.	got7fsn_ti	ER-associated degradation pathway|endoplasmic reticulum-associated protein degradation pathway|protein degradation by ERAD|endoplasmic reticulum-associated degradation				ER-associated protein degradation (ERAD) pathways target misfolded ER lumenal proteins (ERAD-L), ER membrane proteins (ERAD-M), and ER proteins with misfolded cytosolic domains (ERAD-C) by recognizing aberrant proteins, retrotranslocating these substrates to the cytosol, followed by substrate ubiquitination and proteosomal-mediated degradation. In contrast the stress-induced homeostatically regulated protein degradation (SHRED) pathway (GO:0120174), although inducible by stress, targets diverse ER membrane, and cytosolic proteins as well as numerous other native proteins in the absence of stress. Stress results in the protease-mediated (Nma111p) generation of a Roq1p cleavage product that then binds to the type-1 active site of Ubr1p, altering its substrate specificity, and leading to the proteasome-mediated degradation of both misfolded and native proteins. Although the SHRED pathway may contain some components in common with ERAD pathways (GO:0036503), such as UBR1, RAD6 and CDC48, other ERAD components, such as HRD1 and DOA10, do not appear to be involved, and as such these pathways are currently considered to be distinct.		bf	2015-05-14T11:43:06Z						biological_process											owl:Class	
GO:0042812	biolink:NamedThing	pheromone catabolic process	The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.	got7fsn_ti	pheromone breakdown|pheromone degradation|pheromone catabolism										GO:0007327|GO:0046614			biological_process											owl:Class	
GO:0042810	biolink:NamedThing	pheromone metabolic process	The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.	got7fsn_ti	pheromone metabolism													biological_process											owl:Class	
GO:0072497	biolink:NamedThing	mesenchymal stem cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti							mah	2010-12-15T12:59:30Z						biological_process											owl:Class	
GO:0048863	biolink:NamedThing	stem cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.	got7fsn_ti												Wikipedia:Stem_cell_differentiation		biological_process											owl:Class	
GO:0140658	biolink:NamedThing	ATP-dependent chromatin remodeler activity	An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling.	got7fsn_ti	nucleosome-dependent ATPase activity|ATP hydrolysis-dependent chromatin remodeler activity|nucleosome-activated ATPase activity|ATPase-dependent chromatin remodeler activity	https://github.com/geneontology/go-ontology/issues/21786|https://github.com/geneontology/go-ontology/issues/6075|https://github.com/geneontology/go-ontology/issues/21609					pg	2021-06-15T13:57:18Z			GO:0070615			molecular_function											owl:Class	
GO:0002426	biolink:NamedThing	immunoglobulin production in mucosal tissue	The synthesis and release of immunoglobulin in the mucosal tissue.	got7fsn_ti	antibody production in mucosal tissue				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0002381	biolink:NamedThing	immunoglobulin production involved in immunoglobulin-mediated immune response	The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	immunoglobulin production during immune response|immunoglobulin production involved in immune response|immunoglobulin biosynthetic process involved in immune response|immunoglobulin production involved in immunoglobulin mediated immune response|antibody secretion during immune response|immunoglobulin secretion involved in immune response|antibody production during immune response				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0002380|GO:0002379			biological_process											owl:Class	
GO:0047455	biolink:NamedThing	16-alpha-hydroxyprogesterone dehydratase activity	Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.	got7fsn_ti	16-alpha-dehydroxylase activity|16alpha-dehydroxylase activity|16-alpha-hydroxyprogesterone dehydroxylase activity|16alpha-hydroxyprogesterone dehydratase activity|16alpha-hydroxyprogesterone dehydroxylase activity|hydroxyprogesterone dehydroxylase activity|16alpha-hydroxyprogesterone hydro-lyase activity|16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)|16-dehydroprogesterone hydratase activity										GO:0047523	RHEA:12584|EC:4.2.1.98|MetaCyc:4.2.1.98-RXN		molecular_function											owl:Class	
GO:0034414	biolink:NamedThing	tRNA 3'-trailer cleavage, endonucleolytic	Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.	got7fsn_ti	tRNA 3'-end cleavage, endonucleolytic|endonucleolytic tRNA 3'-end cleavage|endonucleolytic tRNA 3'-trailer cleavage													biological_process											owl:Class	
GO:0042779	biolink:NamedThing	tRNA 3'-trailer cleavage	Cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA; may involve endonucleolytic or exonucleolytic cleavage, or both.	got7fsn_ti	removal of tRNA 3'-trailer sequence|tRNA 3'-end cleavage													biological_process											owl:Class	
GO:0008745	biolink:NamedThing	N-acetylmuramoyl-L-alanine amidase activity	Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.	got7fsn_ti	acetylmuramoyl-alanine amidase activity|N-acylmuramyl-L-alanine amidase activity|N-acetylmuramylalanine amidase activity|N-acetylmuramoyl-L-alanine amidase type II|N-acetylmuramic acid L-alanine amidase activity|acetylmuramyl-alanine amidase activity|acetylmuramyl-L-alanine amidase activity|N-acetylmuramyl-L-alanine amidase activity|N-acetylmuramoyl-L-alanine amidase type I											EC:3.5.1.28|MetaCyc:3.5.1.28-RXN|Reactome:R-HSA-6799977		molecular_function											owl:Class	
GO:0018629	biolink:NamedThing	2-hydroxyquinoline 5,6-dioxygenase activity	Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+.	got7fsn_ti	2-oxo-1,2-dihydroquinoline 5,6-dioxygenase activity|quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating)|quinolin-2(1H)-one 5,6-dioxygenase activity|quinolin-2-ol 5,6-dioxygenase activity											MetaCyc:1.14.12.16-RXN|UM-BBD_reactionID:r0052|EC:1.14.12.16|RHEA:10976		molecular_function											owl:Class	
GO:0051048	biolink:NamedThing	negative regulation of secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.	got7fsn_ti	down-regulation of secretion|down regulation of secretion|downregulation of secretion|inhibition of secretion													biological_process											owl:Class	
GO:0150053	biolink:NamedThing	cerebellar climbing fiber to Purkinje cell synapse	A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata.	got7fsn_ti	cerebellar climbing fibre to Purkinje cell synapse						bc	2018-05-09T09:57:20Z						cellular_component											owl:Class	
GO:0098985	biolink:NamedThing	asymmetric, glutamatergic, excitatory synapse	A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials.	got7fsn_ti														cellular_component											owl:Class	
GO:0008126	biolink:NamedThing	acetylesterase activity	Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate.	got7fsn_ti	chloroesterase|acetic-ester acetylhydrolase activity|acetic ester hydrolase activity|p-nitrophenyl acetate esterase|C-esterase (in animal tissues)|citrus acetylesterase											RHEA:12957|UM-BBD_reactionID:r0170|MetaCyc:ACETYLESTERASE-RXN|EC:3.1.1.6		molecular_function											owl:Class	
GO:0034338	biolink:NamedThing	short-chain carboxylesterase activity	Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.	got7fsn_ti	monobutyrase activity|butyrate esterase activity|propionyl esterase activity|short-chain esterase activity|methylbutyrase activity|methylbutyrate esterase activity|butyryl esterase activity													molecular_function											owl:Class	
GO:0009238	biolink:NamedThing	enterobactin metabolic process	The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.	got7fsn_ti	enterochelin metabolic process|enterobactin metabolism|enterochelin metabolism													biological_process											owl:Class	
GO:0009237	biolink:NamedThing	siderophore metabolic process	The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.	got7fsn_ti	siderochrome metabolic process|siderophore metabolism|siderochrome metabolism													biological_process											owl:Class	
GO:0035087	biolink:NamedThing	siRNA loading onto RISC involved in RNA interference	The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC), in the context of RNA interference.	got7fsn_ti	RNA interference, siRNA loading onto RISC													biological_process											owl:Class	
GO:0070922	biolink:NamedThing	small RNA loading onto RISC	The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of gene silencing by small RNA.	got7fsn_ti	RISC assembly|gene silencing by RNA, small RNA loading onto RISC						mah	2009-09-11T03:57:38Z						biological_process											owl:Class	
GO:0070919	biolink:NamedThing	production of siRNA involved in gene silencing by small RNA	Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of gene silencing by small RNA.	got7fsn_ti	production of siRNA involved in chromatin silencing by small RNA|chromatin silencing by small RNA, production of siRNA|chromatin silencing by small RNA, production of guide RNAs|production of guide RNAs involved in chromatin silencing by small RNA	https://github.com/geneontology/go-ontology/issues/22058					mah	2009-09-11T03:39:18Z						biological_process											owl:Class	
GO:0070918	biolink:NamedThing	production of small RNA involved in gene silencing by RNA	The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease.	got7fsn_ti	gene silencing by RNA, production of small RNA|gene silencing by RNA, production of guide RNA						mah	2009-09-11T03:32:19Z						biological_process											owl:Class	
GO:0009340	biolink:NamedThing	DNA topoisomerase IV complex	A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA.	got7fsn_ti														cellular_component											owl:Class	
GO:0009330	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	Complex that possesses DNA topoisomerase II (double strand cut, ATP-hydrolyzing) activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0072002	biolink:NamedThing	Malpighian tubule development	The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.	got7fsn_ti							mah	2010-01-25T10:54:30Z						biological_process											owl:Class	
GO:0002143	biolink:NamedThing	tRNA wobble position uridine thiolation	The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.	got7fsn_ti	tRNA wobble uridine thiolation|wobble position s2U biosynthesis				In E. coli, the first step of the reaction is reductive elimination of sulfur from L-cysteine by IscS cysteine desulfurase to form an enzyme-bound cysteine-persulfide intermediate. Then, five essential gene products, TusA, TusB, TusC, TusD and TusE, mediate a sulfur relay that delivers the terminal sulfur of persulfide from IscS to MnmA12. The last protein, MnmA catalyzes the transfer of the sulfur from IscS to an ATP activated U34 of the tRNA.		hjd	2009-05-06T05:05:40Z						biological_process											owl:Class	
GO:0002098	biolink:NamedThing	tRNA wobble uridine modification	The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.	got7fsn_ti														biological_process											owl:Class	
GO:0034745	biolink:NamedThing	APC-IQGAP1-Rac1 complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.	got7fsn_ti					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0005892	biolink:NamedThing	acetylcholine-gated channel complex	A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.	got7fsn_ti	nicotinic acetylcholine-gated receptor-channel complex|nicotinic acetylcholine receptor													cellular_component											owl:Class	
GO:0034702	biolink:NamedThing	ion channel complex	A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.	got7fsn_ti														cellular_component											owl:Class	
GO:1902492	biolink:NamedThing	positive regulation of sperm capacitation	Any process that activates or increases the frequency, rate or extent of sperm capacitation.	got7fsn_ti	positive regulation of sperm activation|upregulation of sperm capacitation|up-regulation of sperm activation|up regulation of sperm activation|activation of sperm capacitation|upregulation of sperm activation|activation of sperm activation|up regulation of sperm capacitation|up-regulation of sperm capacitation						hjd	2013-11-12T21:17:21Z						biological_process											owl:Class	
GO:1902490	biolink:NamedThing	regulation of sperm capacitation	Any process that modulates the frequency, rate or extent of sperm capacitation.	got7fsn_ti	regulation of sperm activation						hjd	2013-11-12T21:17:03Z						biological_process											owl:Class	
GO:0002191	biolink:NamedThing	cap-dependent translational initiation	The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.	got7fsn_ti							hjd	2011-08-11T02:20:24Z						biological_process											owl:Class	
GO:0002183	biolink:NamedThing	cytoplasmic translational initiation	The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.	got7fsn_ti							hjd	2011-06-09T03:15:48Z						biological_process											owl:Class	
GO:0021787	biolink:NamedThing	chemorepulsion of branchiomotor neuron axon in neural tube	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti	negative chemotaxis of branchiomotor neuron axon in neural tube													biological_process											owl:Class	
GO:0021786	biolink:NamedThing	branchiomotor neuron axon guidance in neural tube	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti														biological_process											owl:Class	
GO:0003330	biolink:NamedThing	regulation of extracellular matrix constituent secretion	Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.	got7fsn_ti							dph	2009-11-02T02:07:40Z						biological_process											owl:Class	
GO:1903530	biolink:NamedThing	regulation of secretion by cell	Any process that modulates the frequency, rate or extent of secretion by cell.	got7fsn_ti	regulation of cellular secretion						pm	2014-10-08T13:24:59Z						biological_process											owl:Class	
GO:0048019	biolink:NamedThing	receptor antagonist activity	The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.	got7fsn_ti	receptor ligand activity													molecular_function											owl:Class	
GO:0030547	biolink:NamedThing	signaling receptor inhibitor activity	Binds to and modulates the activity of a signaling receptor.	got7fsn_ti	receptor inhibitor activity													molecular_function											owl:Class	
GO:0003828	biolink:NamedThing	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.	got7fsn_ti	ganglioside GD3 synthetase sialyltransferase activity|CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase activity|ganglioside GD3 synthase activity|CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity|GD3 synthase activity|CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity|alpha-2,8-sialyltransferase activity|SAT-2|cytidine monophosphoacetylneuraminate-ganglioside GM3											Reactome:R-HSA-1022133|Reactome:R-HSA-4084978|Reactome:R-HSA-422454|RHEA:19313|EC:2.4.99.8|MetaCyc:2.4.99.8-RXN		molecular_function											owl:Class	
GO:0004962	biolink:NamedThing	endothelin receptor activity	Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	endothelin-A receptor activity|endothelin-B receptor activity										GO:0001599|GO:0001600			molecular_function											owl:Class	
GO:0001139	biolink:NamedThing	RNA polymerase II complex recruiting activity	Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.	got7fsn_ti	core RNA polymerase II recruiting transcription factor activity|transcription factor activity, core RNA polymerase II recruiting						krc	2011-01-20T05:55:01Z						molecular_function											owl:Class	
GO:0000993	biolink:NamedThing	RNA polymerase II complex binding	Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.	got7fsn_ti	RNAP II core binding|RNA polymerase II core binding						krc	2010-08-11T03:57:27Z						molecular_function											owl:Class	
GO:0018421	biolink:NamedThing	UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity	Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0004933	biolink:NamedThing	mating-type a-factor pheromone receptor activity	Combining with the mating-type a-factor pheromone to initiate a change in cell activity.	got7fsn_ti	class D G-protein coupled receptor activity|class D GPCR activity|class D G-protein-coupled receptor activity|class D G protein coupled receptor activity													molecular_function											owl:Class	
GO:0004932	biolink:NamedThing	mating-type factor pheromone receptor activity	Combining with a mating-type factor pheromone to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0031152	biolink:NamedThing	aggregation involved in sorocarp development	The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.	got7fsn_ti	aggregate development involved in sorocarp development|aggregation during fruiting body development													biological_process											owl:Class	
GO:0051703	biolink:NamedThing	biological process involved in intraspecies interaction between organisms	Any process in which an organism has an effect on an organism of the same species.	got7fsn_ti	intraspecies interaction between organisms|intraspecies interaction with other organisms	https://github.com/geneontology/go-ontology/issues/20191												biological_process											owl:Class	
GO:0140035	biolink:NamedThing	ubiquitination-like modification-dependent protein binding	Binding to a protein upon modification by a ubiquitin-like protein of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require a ubiquitin-like modification in the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of ubiquitin-like modification. It may be that the modification causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		pg	2017-05-18T06:11:27Z						molecular_function											owl:Class	
GO:0140030	biolink:NamedThing	modification-dependent protein binding	Binding to a protein upon post-translation modification of the target protein.	got7fsn_ti	modified protein binding				This term should only be used when the binding is shown to require a post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T11:50:41Z						molecular_function											owl:Class	
GO:0110092	biolink:NamedThing	nucleus leading edge	The area of a motile nucleus closest to the direction of movement.	got7fsn_ti	horsetail nucleus leading edge						kmv	2018-02-14T22:39:58Z						cellular_component											owl:Class	
GO:2000848	biolink:NamedThing	positive regulation of corticosteroid hormone secretion	Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion.	got7fsn_ti	positive regulation of corticosteroid secretion						bf	2011-07-26T08:43:45Z						biological_process											owl:Class	
GO:2000833	biolink:NamedThing	positive regulation of steroid hormone secretion	Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.	got7fsn_ti							bf	2011-07-26T08:38:51Z						biological_process											owl:Class	
GO:1990630	biolink:NamedThing	IRE1-RACK1-PP2A complex	A protein complex consisting of IRE1 (Inositol-requiring enzyme-1), RACK1 (Receptor of activated protein kinase C 1, GNB2L1) and PP2A (protein phosphatase 2A). RACK1 acts as an adaptor to bridge an interaction between IRE1 and PP2A.	got7fsn_ti	ERN1-RACK1-PP2A complex|IRE1alpha-RACK1-PP2A complex						bf	2015-02-05T15:37:58Z						cellular_component											owl:Class	
GO:0001776	biolink:NamedThing	leukocyte homeostasis	The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti	immune cell homeostasis|leucocyte homeostasis				Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus.									biological_process											owl:Class	
GO:0048872	biolink:NamedThing	homeostasis of number of cells	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.	got7fsn_ti	homeostasis of cell number|cell population homeostasis													biological_process											owl:Class	
GO:0048463	biolink:NamedThing	carpel structural organization	The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	carpel structural organisation										GO:0048432			biological_process											owl:Class	
GO:0048450	biolink:NamedThing	floral organ structural organization	The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	floral organ structural organisation										GO:0048435			biological_process											owl:Class	
GO:0060817	biolink:NamedThing	inactivation of paternal X chromosome	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex.	got7fsn_ti							dph	2009-08-11T10:50:20Z						biological_process											owl:Class	
GO:0009048	biolink:NamedThing	dosage compensation by inactivation of X chromosome	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.	got7fsn_ti	X chromosome inactivation|chromosome inactivation|Barr body formation											Wikipedia:X-inactivation		biological_process											owl:Class	
GO:0001193	biolink:NamedThing	maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.	got7fsn_ti	maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase II promoter						krc	2011-09-02T02:31:00Z						biological_process											owl:Class	
GO:0001192	biolink:NamedThing	maintenance of transcriptional fidelity during DNA-templated transcription elongation	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.	got7fsn_ti	maintenance of transcriptional fidelity during DNA-dependent transcription elongation						krc	2011-09-02T02:25:30Z						biological_process											owl:Class	
GO:0102196	biolink:NamedThing	cortisol dehydrogenase activity	Catalysis of the reaction: cortisol + NADP <=> cortisone + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-12085		molecular_function											owl:Class	
GO:0000931	biolink:NamedThing	gamma-tubulin large complex	A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe.	got7fsn_ti	gamma-tubulin large complex, equatorial microtubule organizing centre|gamma-tubulin ring complex, centrosomal|gamma-tubulin large complex, eMTOC|gamma-tubulin large complex, equatorial microtubule organizing center|gamma-tubulin ring complex|gamma-tubulin large complex, centrosomal|gamma-tubulin large complex, spindle pole body|gamma-tubulin large complex, mitotic spindle pole body|gamma-tubulin large complex, interphase microtubule organizing center|gamma-tubulin large complex, interphase microtubule organizing centre|gamma-tubulin large complex, iMTOC	https://github.com/geneontology/go-ontology/issues/20967									GO:0000929|GO:0055031|GO:0000925|GO:0000926|GO:0055032|GO:0055033|GO:0000924|GO:0061494|GO:0008274			cellular_component											owl:Class	
GO:0000930	biolink:NamedThing	gamma-tubulin complex	A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species.	got7fsn_ti														cellular_component											owl:Class	
GO:0007509	biolink:NamedThing	mesoderm migration involved in gastrulation	The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism.	got7fsn_ti														biological_process											owl:Class	
GO:0090130	biolink:NamedThing	tissue migration	The process in which the population of cells that make up a tissue undergo directed movement.	got7fsn_ti							tb	2009-12-07T03:13:55Z						biological_process											owl:Class	
GO:0050141	biolink:NamedThing	nitroethane oxidase activity	Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2.	got7fsn_ti	nitroethane reductase activity|nitroethane:oxygen oxidoreductase activity											EC:1.7.3.1|MetaCyc:NITROETHANE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0052664	biolink:NamedThing	nitroalkane oxidase activity	Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2.	got7fsn_ti	nitroalkane:oxygen oxidoreductase activity|nitroalkane reductase activity|NAO activity							2010-10-11T10:50:59Z				EC:1.7.3.1|MetaCyc:RXN-11045|KEGG_REACTION:R00799		molecular_function											owl:Class	
GO:0014805	biolink:NamedThing	smooth muscle adaptation	Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.	got7fsn_ti	smooth muscle plasticity													biological_process											owl:Class	
GO:0043500	biolink:NamedThing	muscle adaptation	A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.	got7fsn_ti	muscle plasticity													biological_process											owl:Class	
GO:0032601	biolink:NamedThing	connective tissue growth factor production	The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	Hcs24 production|Fisp12 production|CCN2 production|IGFBP8 production|hypertrophic chondrocyte-specific gene product 24 production|CTGF production													biological_process											owl:Class	
GO:0018865	biolink:NamedThing	acrylonitrile metabolic process	The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.	got7fsn_ti	acrylonitrile metabolism											UM-BBD_pathwayID:acr		biological_process											owl:Class	
GO:0034641	biolink:NamedThing	cellular nitrogen compound metabolic process	The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.	got7fsn_ti	cellular nitrogen compound metabolism													biological_process											owl:Class	
GO:0003405	biolink:NamedThing	optic vesicle elongation	The developmental growth that results in the lengthening of the optic vesicle in the posterior direction.	got7fsn_ti							dph	2009-12-21T01:59:50Z						biological_process											owl:Class	
GO:1900615	biolink:NamedThing	emericellamide A metabolic process	The chemical reactions and pathways involving emericellamide A.	got7fsn_ti	emericellamide A metabolism						di	2012-05-15T07:59:59Z						biological_process											owl:Class	
GO:0036236	biolink:NamedThing	acyl glucuronidation	The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).	got7fsn_ti							bf	2012-05-18T04:26:25Z						biological_process											owl:Class	
GO:0052695	biolink:NamedThing	cellular glucuronidation	The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor.	got7fsn_ti	cellular glucuronide biosynthetic process|cellular glucuronide biosynthesis|cellular glucuronoside biosynthesis|cellular glucuronoside biosynthetic process							2011-07-27T05:28:18Z						biological_process											owl:Class	
GO:0004331	biolink:NamedThing	fructose-2,6-bisphosphate 2-phosphatase activity	Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate.	got7fsn_ti	D-fructose-2,6-bisphosphate 2-phosphohydrolase activity|fructose-2,6-bisphosphatase activity|beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase activity										GO:0004330	Reactome:R-HSA-70262|RHEA:17289|MetaCyc:3.1.3.46-RXN|Reactome:R-HSA-5628905|EC:3.1.3.46		molecular_function											owl:Class	
GO:0034364	biolink:NamedThing	high-density lipoprotein particle	A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.	got7fsn_ti	HDL particle|HDL2|HDL complex|HDL3|high-density lipoprotein class complex													cellular_component											owl:Class	
GO:0070184	biolink:NamedThing	mitochondrial tyrosyl-tRNA aminoacylation	The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0070127	biolink:NamedThing	tRNA aminoacylation for mitochondrial protein translation	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.	got7fsn_ti														biological_process											owl:Class	
GO:0061696	biolink:NamedThing	pituitary gonadotropin complex	A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function.	got7fsn_ti							dph	2015-05-06T13:11:18Z						cellular_component											owl:Class	
GO:0099106	biolink:NamedThing	ion channel regulator activity	Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.	got7fsn_ti														molecular_function											owl:Class	
GO:0090504	biolink:NamedThing	epiboly	The expansion of one cell sheet over other cells or yolk.	got7fsn_ti							tb	2012-10-22T12:29:52Z						biological_process											owl:Class	
GO:0002011	biolink:NamedThing	morphogenesis of an epithelial sheet	The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.	got7fsn_ti														biological_process											owl:Class	
GO:0044345	biolink:NamedThing	stromal-epithelial cell signaling involved in prostate gland development	The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development.	got7fsn_ti	stromal-epithelial cell signalling involved in prostate gland development						jl	2010-08-25T02:06:34Z						biological_process											owl:Class	
GO:0007267	biolink:NamedThing	cell-cell signaling	Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell.  Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.	got7fsn_ti	cell-cell signalling													biological_process											owl:Class	
GO:0061655	biolink:NamedThing	Pup conjugating enzyme activity	Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y -> Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2						dph	2014-11-06T13:30:46Z						molecular_function											owl:Class	
GO:0072496	biolink:NamedThing	Pup transferase activity	Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y --> Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.	got7fsn_ti	Pup conjugating enzyme activity						mah	2010-12-15T11:58:13Z						molecular_function											owl:Class	
GO:0090278	biolink:NamedThing	negative regulation of peptide hormone secretion	Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.	got7fsn_ti							tb	2010-02-05T02:56:39Z						biological_process											owl:Class	
GO:0052312	biolink:NamedThing	modulation of transcription in other organism involved in symbiotic interaction	Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation of transcription in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0090462	biolink:NamedThing	ornithine homeostasis	Any process involved in the maintenance of an internal steady state of ornithine within an organism or cell.	got7fsn_ti							tb	2012-09-24T14:22:02Z						biological_process											owl:Class	
GO:0080144	biolink:NamedThing	amino acid homeostasis	Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell.	got7fsn_ti							dhl	2010-01-27T04:47:27Z						biological_process											owl:Class	
GO:0018296	biolink:NamedThing	protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine	The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine.	got7fsn_ti												RESID:AA0145		biological_process											owl:Class	
GO:0018293	biolink:NamedThing	protein-FAD linkage	The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).	got7fsn_ti														biological_process											owl:Class	
GO:0102979	biolink:NamedThing	homofuraneol oxidoreductase activity	Catalysis of the reaction: homofuraneol + NADP <=> (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+.	got7fsn_ti												RHEA:53944|MetaCyc:RXN-9564		molecular_function											owl:Class	
GO:0140226	biolink:NamedThing	RNA topoisomerase activity	Catalysis of the transient cleavage and passage of individual RNA strands or double helices through one another, resulting a topological transformation in RNA.	got7fsn_ti							pg	2018-05-29T11:06:37Z						molecular_function											owl:Class	
GO:0016853	biolink:NamedThing	isomerase activity	Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.	got7fsn_ti	other isomerase activity											Reactome:R-HSA-6787623|EC:5.-.-.-		molecular_function											owl:Class	
GO:0030540	biolink:NamedThing	female genitalia development	The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.	got7fsn_ti	female genital development													biological_process											owl:Class	
GO:0048806	biolink:NamedThing	genitalia development	The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure.	got7fsn_ti	genital development													biological_process											owl:Class	
GO:0007497	biolink:NamedThing	posterior midgut development	The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0021984	biolink:NamedThing	adenohypophysis development	The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.	got7fsn_ti	anterior pituitary development|adenophysis development|anterior pituitary gland development													biological_process											owl:Class	
GO:0046856	biolink:NamedThing	phosphatidylinositol dephosphorylation	The process of removing one or more phosphate groups from a phosphatidylinositol.	got7fsn_ti	phosphatidylinositol phosphate dephosphorylation|PtdInsP catabolism|PtdInsP dephosphorylation|PIP catabolism|phosphoinositide dephosphorylation|phosphatidylinositol phosphate catabolic process										GO:0046840			biological_process											owl:Class	
GO:0046839	biolink:NamedThing	phospholipid dephosphorylation	The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.	got7fsn_ti														biological_process											owl:Class	
GO:0038083	biolink:NamedThing	peptidyl-tyrosine autophosphorylation	The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein.	got7fsn_ti	receptor tyrosine kinase autophosphorylation|RTK autophosphorylation|tyrosine autophosphorylation						bf	2012-02-01T02:14:18Z						biological_process											owl:Class	
GO:0046777	biolink:NamedThing	protein autophosphorylation	The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).	got7fsn_ti	protein amino acid autophosphorylation											Wikipedia:Autophosphorylation		biological_process											owl:Class	
GO:0001587	biolink:NamedThing	Gq/11-coupled serotonin receptor activity	Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.	got7fsn_ti	serotonin receptor activity, coupled via Gq/11|5-HT2 receptor activity													molecular_function											owl:Class	
GO:0004993	biolink:NamedThing	G protein-coupled serotonin receptor activity	Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.	got7fsn_ti	G protein coupled serotonin receptor activity|5-HT receptor|G-protein coupled serotonin receptor activity|5-hydroxytryptamine receptor	https://github.com/geneontology/go-ontology/issues/12942									GO:0001585|GO:0016609	Wikipedia:5-HT_receptor		molecular_function											owl:Class	
GO:0048649	biolink:NamedThing	caste determination, influence by genetic factors	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.	got7fsn_ti														biological_process											owl:Class	
GO:0048652	biolink:NamedThing	polyphenic determination, influence by genetic factors	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues.	got7fsn_ti														biological_process											owl:Class	
GO:0031783	biolink:NamedThing	type 5 melanocortin receptor binding	Binding to a type 5 melanocortin receptor.	got7fsn_ti	type 5 melanocortin receptor ligand													molecular_function											owl:Class	
GO:0031779	biolink:NamedThing	melanocortin receptor binding	Binding to a melanocortin receptor.	got7fsn_ti	melanocortin receptor ligand													molecular_function											owl:Class	
GO:0051213	biolink:NamedThing	dioxygenase activity	Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.	got7fsn_ti												Reactome:R-HSA-112121|Reactome:R-HSA-112125|Reactome:R-HSA-112124|Reactome:R-HSA-112120		molecular_function											owl:Class	
GO:0047407	biolink:NamedThing	ADP-ribosyl-[dinitrogen reductase] hydrolase activity	Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase].	got7fsn_ti	ADP-D-ribosyl-dinitrogen reductase ADP-ribosylhydrolase activity|ADP-ribosyl glycohydrolase activity|azoferredoxin-activating enzymes|ADP-ribosyl-dinitrogen reductase hydrolase activity|dinitrogenase reductase activating glycohydrolase activity|azoferredoxin glycosidase activity|dinitrogenase reductase-activating glycohydrolase activity											MetaCyc:3.2.2.24-RXN|EC:3.2.2.24|RHEA:14493		molecular_function											owl:Class	
GO:0021964	biolink:NamedThing	rubrospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.	got7fsn_ti														biological_process											owl:Class	
GO:0021952	biolink:NamedThing	central nervous system projection neuron axonogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.	got7fsn_ti	central nervous system axon tract development													biological_process											owl:Class	
GO:0019165	biolink:NamedThing	thiamine kinase activity	Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate.	got7fsn_ti	ATP:thiamine phosphotransferase activity|thiamin phosphokinase activity|thiamin kinase (phosphorylating)|ATP:thiamin phosphotransferase activity|thiamin kinase activity											RHEA:12012|KEGG_REACTION:R02134|EC:2.7.1.89|MetaCyc:THIKIN-RXN		molecular_function											owl:Class	
GO:1904318	biolink:NamedThing	regulation of smooth muscle contraction involved in micturition	Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition.	got7fsn_ti	regulation of smooth muscle contraction involved in urination|regulation of urinary bladder smooth muscle contraction involved in micturition						sl	2015-06-10T18:46:11Z						biological_process											owl:Class	
GO:0044062	biolink:NamedThing	regulation of excretion	Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.	got7fsn_ti														biological_process											owl:Class	
GO:0046155	biolink:NamedThing	rhodopsin catabolic process	The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.	got7fsn_ti	rhodopsin catabolism|rhodopsin degradation|rhodopsin breakdown													biological_process											owl:Class	
GO:0046154	biolink:NamedThing	rhodopsin metabolic process	The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.	got7fsn_ti	rhodopsin metabolism													biological_process											owl:Class	
GO:0102247	biolink:NamedThing	malonyl-malonyl acyl carrier protein-condensing enzyme activity	Catalysis of the reaction: 2 H+ + 2 a malonyl-[acp] <=> 2 carbon dioxide + an acetoacetyl-[acp] + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-12361		molecular_function											owl:Class	
GO:0003376	biolink:NamedThing	sphingosine-1-phosphate receptor signaling pathway	A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	S1P signaling pathway|sphingolipid signaling pathway|S1P receptor signaling pathway|sphingolipid signalling pathway|S1P-activated GPCR signaling pathway|S1P-stimulated signal transduction pathway|S1P-activated G-protein coupled receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/15822					dph	2009-12-09T06:30:12Z			GO:0001789			biological_process											owl:Class	
GO:0007186	biolink:NamedThing	G protein-coupled receptor signaling pathway	A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription.  The pathway can start from the plasma membrane, Golgi or nuclear membrane.	got7fsn_ti	GPCR signalling pathway|dimeric G-protein coupled receptor signalling pathway|G-protein-coupled receptor protein signalling pathway|G-protein coupled receptor signalling pathway|G-protein coupled receptor protein signal transduction|G protein coupled receptor protein signaling pathway|G-protein coupled receptor signaling pathway via GPCR dimer|GPCR signaling pathway|G protein coupled receptor protein signalling pathway|G-protein coupled receptor protein signaling pathway|dimeric G-protein coupled receptor signaling pathway										GO:0038042			biological_process											owl:Class	
GO:0070705	biolink:NamedThing	RNA nucleotide insertion	The modification of an RNA molecule by insertion of one or more nucleotides.	got7fsn_ti							mah	2009-06-08T04:48:35Z						biological_process											owl:Class	
GO:0009451	biolink:NamedThing	RNA modification	The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti	RNA editing				The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing.						GO:0016547	Wikipedia:RNA_editing		biological_process											owl:Class	
GO:0001698	biolink:NamedThing	gastrin-induced gastric acid secretion	The regulated release of gastric acid induced by the interaction of gastrin with its receptor.	got7fsn_ti														biological_process											owl:Class	
GO:0001696	biolink:NamedThing	gastric acid secretion	The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.	got7fsn_ti	hydrochloric acid secretion													biological_process											owl:Class	
GO:0042749	biolink:NamedThing	regulation of circadian sleep/wake cycle	Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0050795	biolink:NamedThing	regulation of behavior	Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.	got7fsn_ti	regulation of behaviour													biological_process											owl:Class	
GO:0071013	biolink:NamedThing	catalytic step 2 spliceosome	A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.	got7fsn_ti	mammalian spliceosomal complex C1|yeast spliceosomal complex A2-2|mammalian spliceosomal complex C						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0004459	biolink:NamedThing	L-lactate dehydrogenase activity	Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.	got7fsn_ti	L-lactic acid dehydrogenase activity|L-lactic dehydrogenase activity											Reactome:R-HSA-71849|Reactome:R-HSA-70510|EC:1.1.1.27|RHEA:23444|MetaCyc:L-LACTATE-DEHYDROGENASE-RXN|Reactome:R-HSA-6807826		molecular_function											owl:Class	
GO:0040040	biolink:NamedThing	thermosensory behavior	Behavior that is dependent upon the sensation of temperature.	got7fsn_ti	behavioral response to temperature stimulus|behavioural response to temperature stimulus|thermosensory behaviour													biological_process											owl:Class	
GO:0009266	biolink:NamedThing	response to temperature stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.	got7fsn_ti	response to thermal stimulus													biological_process											owl:Class	
GO:0106139	biolink:NamedThing	symbiont cell surface	The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	endosymbiont cell surface						hjd	2018-08-15T18:56:57Z						cellular_component											owl:Class	
GO:0044217	biolink:NamedThing	other organism part	Any constituent part of a secondary organism with which the first organism is interacting.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		jl	2009-11-12T01:18:21Z						cellular_component											owl:Class	
GO:0018298	biolink:NamedThing	protein-chromophore linkage	The covalent or noncovalent attachment of a chromophore to a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0090585	biolink:NamedThing	protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0016971	biolink:NamedThing	flavin-linked sulfhydryl oxidase activity	Catalysis of the formation of disulfide bridges in proteins using FAD as the electron acceptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0016972	biolink:NamedThing	thiol oxidase activity	Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O2.	got7fsn_ti	sulfhydryl oxidase activity|thiol:oxygen oxidoreductase activity											RHEA:17357|MetaCyc:THIOL-OXIDASE-RXN|UM-BBD_reactionID:r1293|EC:1.8.3.2		molecular_function											owl:Class	
GO:0052889	biolink:NamedThing	9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene	The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene.	got7fsn_ti	9,9'-di-cis-zeta-carotene catabolism to 7,9,7',9'-tetra-cis-lycopene|7,9,7',9'-tetra-cis-lycopene biosynthesis from 9,9'-di-cis-zeta-carotene											MetaCyc:RXN-12242|KEGG_REACTION:R07511		biological_process											owl:Class	
GO:0016119	biolink:NamedThing	carotene metabolic process	The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.	got7fsn_ti	carotene metabolism													biological_process											owl:Class	
GO:0031637	biolink:NamedThing	regulation of neuronal synaptic plasticity in response to neurotrophin	The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	got7fsn_ti	neurotrophin-induced neuronal synaptic plasticity													biological_process											owl:Class	
GO:0048168	biolink:NamedThing	regulation of neuronal synaptic plasticity	A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	got7fsn_ti					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:0050603	biolink:NamedThing	thiophene-2-carbonyl-CoA monooxygenase activity	Catalysis of the reaction: AH(2) + O(2) + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(2)O + H(+).	got7fsn_ti	thiophene-2-carboxyl-CoA dehydrogenase activity|thiophene-2-carboxyl-CoA monooxygenase activity|thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase activity|thiophene-2-carboxyl-CoA hydroxylase activity											RHEA:18929|MetaCyc:1.14.99.35-RXN|UM-BBD_reactionID:r1235|EC:1.14.99.35|KEGG_REACTION:R05742		molecular_function											owl:Class	
GO:0052801	biolink:NamedThing	bicyclic nitroimidazole metabolic process	The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring.	got7fsn_ti	bicyclic nitroimidazole metabolism													biological_process											owl:Class	
GO:0052802	biolink:NamedThing	nitroimidazole metabolic process	The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.	got7fsn_ti	nitroimidazole metabolism													biological_process											owl:Class	
GO:0097192	biolink:NamedThing	extrinsic apoptotic signaling pathway in absence of ligand	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	extrinsic apoptosis in absence of ligand|dependence receptor signaling pathway|extrinsic apoptotic signalling pathway in absence of ligand				For dependence receptors, absence of a ligand or withdrawal of a ligand from a receptor acts as a signal. An example of 'extrinsic apoptotic signaling pathway in absence of ligand' is withdrawal of a growth factor such as NGF, even if traditionally apoptosis induced via growth factor withdrawal has been classified as an instance of intrinsic apoptosis. See an example in PMID:19767770. Ligands whose withdrawal or absence induce apoptosis should be annotated to GO:2001239 'regulation of extrinsic apoptotic signaling pathway in absence of ligand', rather than to the pathway term itself. Examples of gene products that may be annotated to GO:0097192 'extrinsic apoptotic signaling pathway in absence of ligand' include dependence receptors such as DCC or UNC5B, which relay lethal signals in the absence of their ligand (netrin-1). In the case of DCC and UNC5B, the signaling proceeds through the assembly of a DRAL- and TUCAN- (or NLRP1-) containing caspase-9-activating complex or by the dephosphorylation-mediated activation of death-associated protein kinase 1 (DAPK1) by UNC5B-bound protein phosphatase 2A (PP2A), respectively. DAPK1 can mediate the direct activation of executioner caspases or favor MOMP (reviewed in PMID:21760595). Also see PMID:21172653 (annotations to UNC5B and PR65beta, UniProt symbols O08722, PPP2R1B and P30154).		pr	2011-11-23T09:37:09Z						biological_process											owl:Class	
GO:0039580	biolink:NamedThing	suppression by virus of host PKR signaling	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (Protein Kinase regulated by RNA) signaling. Host PKR signaling includes targets such as the translation initiation factor eIF2alpha,  inhibiting protein synthesis as an antiviral response.	got7fsn_ti	suppression by virus of host EIF2AK2 activity|suppression by virus of host PKR activity	https://github.com/geneontology/go-ontology/issues/21971					bf							biological_process											owl:Class	
GO:0019057	biolink:NamedThing	modulation by virus of host translation	Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA.	got7fsn_ti	viral host shutoff protein|host cell shutoff|regulation of host mRNA translation by virus|modulation of host translation by virus|regulation of host translation by virus|viral perturbation of host cell mRNA translation|regulation of translation in host by virus|host cell protein synthesis shutoff|modification by virus of host cell mRNA translation													biological_process											owl:Class	
GO:0045841	biolink:NamedThing	negative regulation of mitotic metaphase/anaphase transition	Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.	got7fsn_ti	inhibition of mitotic metaphase/anaphase transition|downregulation of mitotic metaphase/anaphase transition|down-regulation of mitotic metaphase/anaphase transition|down regulation of mitotic metaphase/anaphase transition													biological_process											owl:Class	
GO:0045839	biolink:NamedThing	negative regulation of mitotic nuclear division	Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.	got7fsn_ti	inhibition of mitosis|negative regulation of mitosis|down regulation of mitosis|down-regulation of mitosis|downregulation of mitosis													biological_process											owl:Class	
GO:0035011	biolink:NamedThing	melanotic encapsulation of foreign target	Formation of a multilayered, melanized sheath of cells around a foreign invader.	got7fsn_ti														biological_process											owl:Class	
GO:0035010	biolink:NamedThing	encapsulation of foreign target	Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization.	got7fsn_ti														biological_process											owl:Class	
GO:0061324	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation						dph	2010-09-28T09:19:37Z						biological_process											owl:Class	
GO:0061316	biolink:NamedThing	canonical Wnt signaling pathway involved in heart development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in heart development|canonical Wnt receptor signalling pathway involved in heart development|canonical Wnt-activated signaling pathway involved in heart development						dph	2010-09-24T09:25:03Z						biological_process											owl:Class	
GO:0052131	biolink:NamedThing	positive aerotaxis	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen.	got7fsn_ti														biological_process											owl:Class	
GO:0009454	biolink:NamedThing	aerotaxis	The directed movement of a motile cell or organism in response to environmental oxygen.	got7fsn_ti	taxis in response to atmospheric oxygen													biological_process											owl:Class	
GO:0048307	biolink:NamedThing	ferredoxin-nitrite reductase activity	Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+.	got7fsn_ti	ammonia:ferredoxin oxidoreductase activity											MetaCyc:FERREDOXIN--NITRITE-REDUCTASE-RXN|EC:1.7.7.1|RHEA:18041		molecular_function											owl:Class	
GO:0098809	biolink:NamedThing	nitrite reductase activity	Catalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0002694	biolink:NamedThing	regulation of leukocyte activation	Any process that modulates the frequency, rate, or extent of leukocyte activation.	got7fsn_ti	regulation of leucocyte activation|regulation of immune cell activation													biological_process											owl:Class	
GO:0035184	biolink:NamedThing	histone threonine kinase activity	Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic  chromosomes.	got7fsn_ti	histone-threonine kinase activity													molecular_function											owl:Class	
GO:0035173	biolink:NamedThing	histone kinase activity	Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.	got7fsn_ti														molecular_function											owl:Class	
GO:0120242	biolink:NamedThing	2-iminobutanoate deaminase activity	Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+).	got7fsn_ti	2-iminobutanoate/2-iminopropanoate deaminase	https://github.com/geneontology/go-ontology/issues/19832					krc	2020-07-29T18:07:00Z				KEGG_REACTION:R11098|MetaCyc:RXN-15123|RHEA:39975		molecular_function											owl:Class	
GO:0120241	biolink:NamedThing	2-iminobutanoate/2-iminopropanoate deaminase	Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.	got7fsn_ti	imine intermediate deaminase activity|2-iminopropanoate deaminase|2-iminobutanoate deaminase|enamine/imine deaminase	https://github.com/geneontology/go-ontology/issues/19832			This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates (from EC:3.5.99.10).		krc	2020-07-29T17:28:19Z				EC:3.5.99.10		molecular_function											owl:Class	
GO:0016159	biolink:NamedThing	muconolactone delta-isomerase activity	Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate.	got7fsn_ti	muconolactone isomerase activity|5-oxo-4,5-dihydrofuran-2-acetate delta3-delta2-isomerase activity|muconolactone D-isomerase activity											RHEA:12348|MetaCyc:MUCONOLACTONE-DELTA-ISOMERASE-RXN|EC:5.3.3.4		molecular_function											owl:Class	
GO:0016863	biolink:NamedThing	intramolecular oxidoreductase activity, transposing C=C bonds	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears.	got7fsn_ti	intramolecular isomerase activity, transposing C=C bonds											EC:5.3.3.-		molecular_function											owl:Class	
GO:0017024	biolink:NamedThing	myosin I binding	Binding to a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments.	got7fsn_ti														molecular_function											owl:Class	
GO:0017022	biolink:NamedThing	myosin binding	Binding to a myosin; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.	got7fsn_ti	myosin phosphatase myosin binding													molecular_function											owl:Class	
GO:0047200	biolink:NamedThing	tetrahydrodipicolinate N-acetyltransferase activity	Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA.	got7fsn_ti	tetrahydrodipicolinate:acetyl-CoA acetyltransferase activity|acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase activity|tetrahydrodipicolinate acetylase activity|acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate 2-N-acetyltransferase activity|acetyl-CoA:(S)-2,3,4,5-tetrahydrodipicolinate-2,6-dicarboxylate N2-acetyltransferase activity											RHEA:13085|MetaCyc:2.3.1.89-RXN|KEGG_REACTION:R04364|EC:2.3.1.89		molecular_function											owl:Class	
GO:0031509	biolink:NamedThing	subtelomeric heterochromatin assembly	The assembly of chromatin into heterochromatin at the subtelomeric region, resulting in a chromatin conformation refractory to transcription.	got7fsn_ti	Telomere Position Effect|telomeric heterochromatin assembly|chromatin silencing at subtelomere|heterochromatic silencing at subtelomere|regulation of chromatin silencing at telomere|establishment of chromatin silencing at telomere|telomere chromatin silencing|telomeric heterochromatin formation|chromatin silencing at telomere|telomeric silencing|subtelomere chromatin silencing|subtelomeric silencing|regulation of subtelomeric heterochromatin assembly|heterochromatic silencing at telomere	https://github.com/geneontology/go-ontology/issues/22027|https://github.com/geneontology/go-ontology/issues/19308|https://github.com/geneontology/go-ontology/issues/19188									GO:0099114|GO:0006348|GO:0035390			biological_process											owl:Class	
GO:0042653	biolink:NamedThing	mitochondrial respiratory chain complex I, membrane segment	The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.	got7fsn_ti	NADH-Q oxidoreductase complex, membrane segment													cellular_component											owl:Class	
GO:0098798	biolink:NamedThing	mitochondrial protein-containing complex	A protein complex that is part of a mitochondrion.	got7fsn_ti	mitochondrial protein complex				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									cellular_component											owl:Class	
GO:0050385	biolink:NamedThing	ureidoglycolate lyase activity	Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea.	got7fsn_ti	ureidoglycolate hydrolase activity|ureidoglycolatase activity|(S)-ureidoglycolate urea-lyase activity|(S)-ureidoglycolate urea-lyase (glyoxylate-forming)|ureidoglycolase activity				Take care to annotate to the reaction, not simply by enzyme name. Note that the name "ureidoglycolate hydrolase" (listed as a synonym here) has variously been used to refer to two distinctly different enzymes. Both enzymes act on ureidoglycolate and produce glyoxylate, but the mechanism and reaction products are different. The "ureidoglycolate hydrolase" listed in the Enzyme commission (EC) is a ureidoglycolate amidohydrolase, releasing ammonia, (EC:3.5.3.19 ; GO:0004848). The "ureidoglycolate hydrolase" characterized in PMID:3915539 (published prior to the EC designation of EC:3.5.3.19) is a ureidoglycolate lyase, releasing urea (EC:4.3.2.3 ; GO:0050385). The inappropriate labelling of ureidoglycolate lyase as EC:3.5.3.19 has caused much confusion in the literature (see PMID:24107613). Take care to correctly annotate based on the reaction products, rather than name.							MetaCyc:UREIDOGLYCOLATE-LYASE-RXN|KEGG_REACTION:R00776|EC:4.3.2.3|RHEA:11304		molecular_function											owl:Class	
GO:0016842	biolink:NamedThing	amidine-lyase activity	Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.	got7fsn_ti												EC:4.3.2.-		molecular_function											owl:Class	
GO:0009690	biolink:NamedThing	cytokinin metabolic process	The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.	got7fsn_ti	cytokinin metabolism													biological_process											owl:Class	
GO:0006725	biolink:NamedThing	cellular aromatic compound metabolic process	The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.	got7fsn_ti	aromatic compound metabolism|aromatic hydrocarbon metabolic process|aromatic hydrocarbon metabolism													biological_process											owl:Class	
GO:0080082	biolink:NamedThing	esculin beta-glucosidase activity	Catalysis of the hydrolysis of glucosidic link in esculin.	got7fsn_ti							dhl	2009-04-14T04:09:42Z						molecular_function											owl:Class	
GO:0008422	biolink:NamedThing	beta-glucosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.	got7fsn_ti	primeverosidase activity|arbutinase activity|salicilinase activity|gentobiase activity|elaterase activity|beta-glucoside glucohydrolase activity|limarase activity|gentiobiase activity|aryl-beta-glucosidase activity|beta-D-glucosidase activity|cytokine beta-glucosidase activity|beta-D-glucoside glucohydrolase activity|emulsin|beta-1,6-glucosidase activity|cellobiase activity|amygdalase activity|amygdalinase|p-nitrophenyl beta-glucosidase activity										GO:0016983	MetaCyc:3.2.1.21-RXN|EC:3.2.1.21		molecular_function											owl:Class	
GO:0004527	biolink:NamedThing	exonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.	got7fsn_ti	exonuclease IX activity										GO:0008857			molecular_function											owl:Class	
GO:0004518	biolink:NamedThing	nuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids.	got7fsn_ti					Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.									molecular_function											owl:Class	
GO:0018553	biolink:NamedThing	3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity	Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.	got7fsn_ti												UM-BBD_enzymeID:e0309		molecular_function											owl:Class	
GO:0071454	biolink:NamedThing	cellular response to anoxia	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.	got7fsn_ti	cellular response to anoxic stress|cellular response to anaerobic conditions				Note that this term should not be confused with 'cellular response to hypoxia ; GO:0071456'.		mah	2009-12-16T04:44:20Z						biological_process											owl:Class	
GO:0080114	biolink:NamedThing	positive regulation of glycine hydroxymethyltransferase activity	Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.	got7fsn_ti							dhl	2009-04-27T03:27:15Z						biological_process											owl:Class	
GO:0006895	biolink:NamedThing	Golgi to endosome transport	The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.	got7fsn_ti	TGN to endosome transport|Golgi to endosome vesicle-mediated transport|trans-Golgi to endosome transport										GO:0048218			biological_process											owl:Class	
GO:0009604	biolink:NamedThing	detection of symbiotic bacterium	The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal.	got7fsn_ti	perception of symbiotic bacteria|detection of symbiotic bacteria|perception of symbiotic bacterium													biological_process											owl:Class	
GO:0009602	biolink:NamedThing	detection of symbiont	The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	perception of symbiont|recognition of symbiont	https://github.com/geneontology/go-ontology/issues/17977									GO:0051855			biological_process											owl:Class	
GO:0061626	biolink:NamedThing	pharyngeal arch artery morphogenesis	The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.	got7fsn_ti	aortic arch artery morphogenesis						dph	2014-05-09T15:34:06Z						biological_process											owl:Class	
GO:0048844	biolink:NamedThing	artery morphogenesis	The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.	got7fsn_ti	arteriogenesis|arterial morphogenesis													biological_process											owl:Class	
GO:0018756	biolink:NamedThing	ammeline aminohydrolase activity	Catalysis of the reaction: ammeline + H2O = ammelide + NH3.	got7fsn_ti												MetaCyc:RXN-8016|RHEA:26201		molecular_function											owl:Class	
GO:0016813	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.	got7fsn_ti												EC:3.5.3.-		molecular_function											owl:Class	
GO:0035224	biolink:NamedThing	genital disc anterior/posterior pattern formation	The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).	got7fsn_ti														biological_process											owl:Class	
GO:0007448	biolink:NamedThing	anterior/posterior pattern specification, imaginal disc	The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form.	got7fsn_ti														biological_process											owl:Class	
GO:0047103	biolink:NamedThing	3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity	Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate.	got7fsn_ti	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase activity|3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-dehydrogenase activity|THAL-NAD oxidoreductase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al dehydrogenase activity|cholestanetriol-26-al 26-dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-dehydrogenase activity|trihydroxydeoxycoprostanal dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase activity											MetaCyc:1.2.1.40-RXN|RHEA:24584		molecular_function											owl:Class	
GO:0002167	biolink:NamedThing	VRK3/VHR/ERK complex	A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway.	got7fsn_ti							hjd	2010-03-04T01:15:05Z						cellular_component											owl:Class	
GO:0021626	biolink:NamedThing	central nervous system maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	got7fsn_ti														biological_process											owl:Class	
GO:0060830	biolink:NamedThing	ciliary receptor clustering involved in smoothened signaling pathway	Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.	got7fsn_ti	ciliary receptor clustering involved in hedgehog signaling pathway|ciliary receptor clustering involved in smoothened signalling pathway|ciliary receptor clustering involved in hh signaling pathway						dph	2009-08-11T02:06:33Z						biological_process											owl:Class	
GO:0043113	biolink:NamedThing	receptor clustering	The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.	got7fsn_ti														biological_process											owl:Class	
GO:0005581	biolink:NamedThing	collagen trimer	A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.	got7fsn_ti												Wikipedia:Collagen		cellular_component											owl:Class	
GO:0002702	biolink:NamedThing	positive regulation of production of molecular mediator of immune response	Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.	got7fsn_ti	upregulation of production of molecular mediator of immune response|up regulation of production of molecular mediator of immune response|stimulation of production of molecular mediator of immune response|up-regulation of production of molecular mediator of immune response|activation of production of molecular mediator of immune response													biological_process											owl:Class	
GO:0002700	biolink:NamedThing	regulation of production of molecular mediator of immune response	Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.	got7fsn_ti														biological_process											owl:Class	
GO:0060242	biolink:NamedThing	contact inhibition	The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation.	got7fsn_ti	detection of cell density by contact stimulus involved in contact inhibition|detection of cell density by contact stimulus										GO:0060248|GO:0060246	Wikipedia:Contact_inhibition		biological_process											owl:Class	
GO:0060245	biolink:NamedThing	detection of cell density	The series of events in which information about the density of cells in a population is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0046940	biolink:NamedThing	nucleoside monophosphate phosphorylation	The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside.	got7fsn_ti														biological_process											owl:Class	
GO:0009123	biolink:NamedThing	nucleoside monophosphate metabolic process	The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	nucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0000411	biolink:NamedThing	positive regulation of transcription by galactose	Any process involving galactose that activates or increases the rate of transcription.	got7fsn_ti	up regulation of transcription by galactose|stimulation of transcription by galactose|activation of transcription by galactose|up-regulation of transcription by galactose|upregulation of transcription by galactose													biological_process											owl:Class	
GO:0010327	biolink:NamedThing	acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate.	got7fsn_ti	hexenol acetyltransferase													molecular_function											owl:Class	
GO:0005550	biolink:NamedThing	pheromone binding	Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.	got7fsn_ti														molecular_function											owl:Class	
GO:0005549	biolink:NamedThing	odorant binding	Binding to an odorant, any substance capable of stimulating the sense of smell.	got7fsn_ti														molecular_function											owl:Class	
GO:0009455	biolink:NamedThing	redox taxis	The directed movement of a motile cell or organism in response to redox potential.	got7fsn_ti	redoxtaxis|taxis in response to redox potential|taxis in response to redox stimulus													biological_process											owl:Class	
GO:0051775	biolink:NamedThing	response to redox state	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.	got7fsn_ti	redox signal response										GO:0006980			biological_process											owl:Class	
GO:0044176	biolink:NamedThing	host cell filopodium	Thin, stiff protrusion extended by the leading edge of a motile host cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.	got7fsn_ti	host filopodium						jl	2009-09-04T03:06:59Z						cellular_component											owl:Class	
GO:0044157	biolink:NamedThing	host cell projection	A prolongation or process extending from a host cell, e.g. a flagellum or axon.	got7fsn_ti							jl	2009-08-11T04:07:24Z						cellular_component											owl:Class	
GO:0016714	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor.	got7fsn_ti												EC:1.14.16.-		molecular_function											owl:Class	
GO:0034996	biolink:NamedThing	RasGAP-Fyn-Lyn-Yes complex	A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation.	got7fsn_ti	p21(ras)GAP-Fyn-Lyn-Yes complex, thrombin stimulated				Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0039503	biolink:NamedThing	suppression by virus of host innate immune response	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense.	got7fsn_ti	negative regulation by virus of host innate immune response|inhibition of host innate immune response by virus|negative regulation by virus of host innate immunity|suppression by virus of host innate immunity						bf	2011-05-11T04:31:17Z						biological_process											owl:Class	
GO:0102050	biolink:NamedThing	indole-3-acetyl-tyrosine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-tyrosine + ATP(4-) <=> H+ + indole-3-acetyl-tyrosine + AMP(2-) + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10432		molecular_function											owl:Class	
GO:0016879	biolink:NamedThing	ligase activity, forming carbon-nitrogen bonds	Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti	other carbon-nitrogen ligase activity											EC:6.3.-.-		molecular_function											owl:Class	
GO:0050029	biolink:NamedThing	L-lysine oxidase activity	Catalysis of the reaction: L-lysine + H(2)O + O(2) = 6-amino-2-oxohexanoate + H(2)O(2) + NH(4)(+).	got7fsn_ti	L-lysyl-alpha-oxidase activity|L-lysine:oxygen 2-oxidoreductase (deaminating)|L-lysine alpha-oxidase activity											EC:1.4.3.14|MetaCyc:PWY-5311|KEGG_REACTION:R00447|MetaCyc:L-LYSINE-OXIDASE-RXN|RHEA:14437		molecular_function											owl:Class	
GO:0001716	biolink:NamedThing	L-amino-acid oxidase activity	Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.	got7fsn_ti	L-amino-acid:oxygen oxidoreductase (deaminating)|ophio-amino-acid oxidase activity											RHEA:13781|MetaCyc:L-AMINO-ACID-OXIDASE-RXN|Reactome:R-HSA-2160492|EC:1.4.3.2		molecular_function											owl:Class	
GO:0047860	biolink:NamedThing	diiodophenylpyruvate reductase activity	Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH.	got7fsn_ti	3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase activity|KAR|aromatic alpha-keto acid|2-oxo acid reductase activity											KEGG_REACTION:R03431|RHEA:20293|MetaCyc:DIIODOPHENYLPYRUVATE-REDUCTASE-RXN|EC:1.1.1.96		molecular_function											owl:Class	
GO:0061154	biolink:NamedThing	endothelial tube morphogenesis	The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.	got7fsn_ti							dph	2010-06-15T09:05:00Z						biological_process											owl:Class	
GO:0003159	biolink:NamedThing	morphogenesis of an endothelium	The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.	got7fsn_ti							dph	2009-10-01T01:34:06Z						biological_process											owl:Class	
GO:0044855	biolink:NamedThing	plasma membrane raft distribution	The process that establishes the spatial arrangement of membrane rafts within a plasma membrane.	got7fsn_ti							jl	2014-07-23T16:00:41Z						biological_process											owl:Class	
GO:0044856	biolink:NamedThing	plasma membrane raft localization	Any process in which plasma membrane rafts are transported to, or maintained in, a specific location.	got7fsn_ti							jl	2014-07-23T16:12:22Z						biological_process											owl:Class	
GO:0034376	biolink:NamedThing	conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle	The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.	got7fsn_ti	discoidal high-density lipoprotein remodeling|discoidal HDL remodeling|conversion of discoidal HDL to spherical HDL													biological_process											owl:Class	
GO:0034375	biolink:NamedThing	high-density lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.	got7fsn_ti	HDL remodeling													biological_process											owl:Class	
GO:0010842	biolink:NamedThing	retina layer formation	The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.	got7fsn_ti	retinal layer formation|retinal lamination													biological_process											owl:Class	
GO:0052795	biolink:NamedThing	exo-alpha-(2->6)-sialidase activity	Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates.	got7fsn_ti	exo-alpha-2,6-sialidase activity|exo-alpha-(2,6)-sialidase activity											EC:3.2.1.18		molecular_function											owl:Class	
GO:0004308	biolink:NamedThing	exo-alpha-sialidase activity	Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.	got7fsn_ti	alpha-neuraminidase activity|acetylneuraminyl hydrolase activity|acetylneuraminidase activity|N-acylneuraminate glycohydrolase activity|neuraminidase activity|sialidase activity											Reactome:R-HSA-4085029|Reactome:R-HSA-1605724|Reactome:R-HSA-4084994|Reactome:R-HSA-168870|EC:3.2.1.18|Reactome:R-HSA-4341669|Reactome:R-HSA-1605768|Reactome:R-HSA-1605723|Reactome:R-HSA-9638120|MetaCyc:3.2.1.18-RXN|Reactome:R-HSA-4084999		molecular_function											owl:Class	
GO:1990665	biolink:NamedThing	AnxA2-p11 complex	A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10).	got7fsn_ti	(p11)2.(AnxA2)2 complex|AnxA2.p11 complex|AnxA2:S100A10 heterotetramer|Annexin A2 tetramer|Annexin A2-p11 complex|(A2.p11)2 complex						bf	2015-03-02T10:07:42Z						cellular_component											owl:Class	
GO:0009972	biolink:NamedThing	cytidine deamination	The removal of amino group in the presence of water.	got7fsn_ti														biological_process											owl:Class	
GO:0006216	biolink:NamedThing	cytidine catabolic process	The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside.	got7fsn_ti	cytidine degradation|cytidine catabolism|cytidine breakdown													biological_process											owl:Class	
GO:0045055	biolink:NamedThing	regulated exocytosis	A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand.	got7fsn_ti	regulated secretory pathway													biological_process											owl:Class	
GO:0006887	biolink:NamedThing	exocytosis	A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.	got7fsn_ti	nonselective vesicle exocytosis|vesicle exocytosis										GO:0016194|GO:0016195	Wikipedia:Exocytosis		biological_process											owl:Class	
GO:0051507	biolink:NamedThing	beta-sitosterol UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a beta-sitosterol = UDP + O-glucosyl-beta-sitosterol.	got7fsn_ti												RHEA:61832|MetaCyc:RXN-12128		molecular_function											owl:Class	
GO:0016906	biolink:NamedThing	sterol 3-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol.	got7fsn_ti	sterol:UDPG glucosyltransferase activity|sterol 3beta-glucosyltransferase activity|UDPG:sterol glucosyltransferase activity|sterol-beta-D-glucosyltransferase activity|UDPglucose:sterol 3-O-beta-D-glucosyltransferase activity|UDP-glucose:sterol glucosyltransferase activity|UDP-glucose:sterol 3-O-beta-D-glucosyltransferase activity|UDP-glucose-sterol beta-glucosyltransferase activity|UDPG-SGTase activity|sterol glucosyltransferase activity|uridine diphosphoglucose-poriferasterol glucosyltransferase activity|UDP-glucose-sterol glucosyltransferase activity|uridine diphosphoglucose-sterol glucosyltransferase activity											EC:2.4.1.173|MetaCyc:STEROL-GLUCOSYLTRANSFERASE-RXN|RHEA:22724		molecular_function											owl:Class	
GO:0000971	biolink:NamedThing	tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate	A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans.	got7fsn_ti							krc	2009-04-28T10:36:17Z						biological_process											owl:Class	
GO:0000968	biolink:NamedThing	tRNA exon ligation	An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed.	got7fsn_ti							krc	2009-04-28T10:22:40Z						biological_process											owl:Class	
GO:0097580	biolink:NamedThing	intracellular sequestering of copper ion	The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.	got7fsn_ti	intracellular retention of copper ion|intracellular storage of copper ion|intracellular copper ion sequestering|intracellular copper ion storage|intracellular sequestration of copper ion|intracellular copper ion retention|intracellular copper ion sequestration						pr	2014-02-28T11:21:39Z						biological_process											owl:Class	
GO:0051651	biolink:NamedThing	maintenance of location in cell	Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.	got7fsn_ti	retention within cell|sequestering within cell|cellular retention|storage within cell|cellular storage|intracellular retention|maintenance of intracellular localization|maintenance of localization in cell|maintenance of localization within cell|cellular sequestering|intracellular sequestering|maintenance of cellular localization|intracellular storage													biological_process											owl:Class	
GO:0046878	biolink:NamedThing	positive regulation of saliva secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of saliva.	got7fsn_ti	up-regulation of saliva secretion|activation of saliva secretion|stimulation of saliva secretion|up regulation of saliva secretion|upregulation of saliva secretion													biological_process											owl:Class	
GO:0060456	biolink:NamedThing	positive regulation of digestive system process	Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0016295	biolink:NamedThing	myristoyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate.	got7fsn_ti	myristoyl-ACP hydrolase activity|tetradecanoyl-ACP hydrolase activity|myristoyl-[acyl-carrier protein] hydrolase activity|tetradecanoyl-[acyl-carrier-protein] hydrolase activity											RHEA:30123|EC:3.1.2.14|MetaCyc:RXN-10727|KEGG_REACTION:R08159		molecular_function											owl:Class	
GO:0016297	biolink:NamedThing	acyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid.	got7fsn_ti	acyl-ACP-hydrolase activity|acyl-acyl carrier protein hydrolase activity|acyl-ACP thioesterase activity|acyl-[acyl-carrier protein] hydrolase activity|acyl-ACP hydrolase activity|acyl-acyl-carrier-protein hydrolase activity|S-acyl fatty acid synthase thioesterase activity										GO:0010281	Reactome:R-HSA-5655955|EC:3.1.2.14|RHEA:30131|MetaCyc:RXN-7902		molecular_function											owl:Class	
GO:0090194	biolink:NamedThing	negative regulation of glomerulus development	Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.	got7fsn_ti							tb	2009-12-18T11:17:13Z						biological_process											owl:Class	
GO:0090185	biolink:NamedThing	negative regulation of kidney development	Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti	negative regulation of nephrogenesis						tb	2009-12-18T10:58:45Z						biological_process											owl:Class	
GO:0016275	biolink:NamedThing	[cytochrome c]-arginine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine.	got7fsn_ti	cytochrome c-arginine N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-arginine nomega-methyltransferasea|S-adenosyl-L-methionine:cytochrome c-arginine omega-N-methyltransferasea											RHEA:21872|EC:2.1.1.124|MetaCyc:2.1.1.124-RXN		molecular_function											owl:Class	
GO:0016274	biolink:NamedThing	protein-arginine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.	got7fsn_ti	PRMT activity											Reactome:R-HSA-5229203|Reactome:R-HSA-5205798|Reactome:R-HSA-8879123|Reactome:R-HSA-191790|Reactome:R-HSA-5205820|Reactome:R-HSA-5205824|Reactome:R-HSA-5205822|Reactome:R-HSA-5229010|Reactome:R-HSA-5218952|Reactome:R-HSA-8934735|Reactome:R-HSA-5661126|Reactome:R-HSA-5205867		molecular_function											owl:Class	
GO:1990711	biolink:NamedThing	beta-catenin-ICAT complex	Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex.	got7fsn_ti	Beta-catenin-ICAT complex|CTNNB1-CTNNBIP1 complex				An example of this is Catenin beta-1 in human (UniProt symbol P35222) in PMID:12408824 (inferred from physical interaction).		bhm	2015-03-25T21:08:11Z						cellular_component											owl:Class	
GO:0090571	biolink:NamedThing	RNA polymerase II transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase II promoter.	got7fsn_ti							tb	2014-05-09T13:26:16Z						cellular_component											owl:Class	
GO:0070275	biolink:NamedThing	aerobic ammonia oxidation to nitrite via pyruvic oxime	The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite.	got7fsn_ti												MetaCyc:PWY-2242		biological_process											owl:Class	
GO:0019329	biolink:NamedThing	ammonia oxidation	The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons.	got7fsn_ti														biological_process											owl:Class	
GO:1990751	biolink:NamedThing	Schwann cell chemotaxis	The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti							sl	2015-05-21T19:19:09Z						biological_process											owl:Class	
GO:0036135	biolink:NamedThing	Schwann cell migration	The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function.	got7fsn_ti							bf	2012-03-06T10:44:39Z						biological_process											owl:Class	
GO:0033043	biolink:NamedThing	regulation of organelle organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.	got7fsn_ti	regulation of organelle organisation|regulation of organelle organization and biogenesis													biological_process											owl:Class	
GO:0051128	biolink:NamedThing	regulation of cellular component organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.	got7fsn_ti	regulation of cellular component organisation|regulation of cell organization|regulation of cellular component organization and biogenesis|regulation of cell organisation													biological_process											owl:Class	
GO:0031128	biolink:NamedThing	developmental induction	A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder).	got7fsn_ti														biological_process											owl:Class	
GO:0042925	biolink:NamedThing	benzoate transmembrane transporter activity	Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other.	got7fsn_ti	benzoate transporter activity											RHEA:32811		molecular_function											owl:Class	
GO:0052877	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor.	got7fsn_ti												EC:1.4.9.-		molecular_function											owl:Class	
GO:0060508	biolink:NamedThing	lung basal cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.	got7fsn_ti	pulmonary basal cell differentiation													biological_process											owl:Class	
GO:0060479	biolink:NamedThing	lung cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti	pulmonary cell differentiation													biological_process											owl:Class	
GO:0003949	biolink:NamedThing	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity	Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.	got7fsn_ti	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase activity|N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase activity|N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase activity|1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase activity|phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase activity|phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase activity											EC:5.3.1.16|RHEA:15469|KEGG_REACTION:R04640|MetaCyc:PRIBFAICARPISOM-RXN		molecular_function											owl:Class	
GO:0033473	biolink:NamedThing	indoleacetic acid conjugate metabolic process	The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.	got7fsn_ti	IAA conjugate metabolic process|indole acetic acid conjugate metabolic process|indole acetic acid conjugate metabolism|indoleacetic acid conjugate metabolism													biological_process											owl:Class	
GO:0009683	biolink:NamedThing	indoleacetic acid metabolic process	The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants.	got7fsn_ti	indole acetic acid metabolism|IAA metabolic process|indoleacetic acid metabolism|indole acetic acid metabolic process													biological_process											owl:Class	
GO:0071736	biolink:NamedThing	IgG immunoglobulin complex, circulating	A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	IgG2a antibody|IgG2b antibody|IgG4 antibody|IgG3 antibody|IgG2 antibody|IgG antibody|IgG1 antibody|IgG2c antibody				Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0006336	biolink:NamedThing	DNA replication-independent nucleosome assembly	The formation of nucleosomes outside the context of DNA replication.	got7fsn_ti	transcription-coupled nucleosome assembly													biological_process											owl:Class	
GO:0034724	biolink:NamedThing	DNA replication-independent nucleosome organization	The formation or destruction of chromatin structures, occurring outside the context of DNA replication.	got7fsn_ti	DNA replication-independent nucleosome organisation													biological_process											owl:Class	
GO:0009039	biolink:NamedThing	urease activity	Catalysis of the reaction: urea + H2O = CO2 + 2 NH3.	got7fsn_ti	urea amidohydrolase activity											MetaCyc:UREASE-RXN|UM-BBD_reactionID:r0120|RHEA:20557|EC:3.5.1.5		molecular_function											owl:Class	
GO:0010214	biolink:NamedThing	seed coat development	The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0034645	biolink:NamedThing	cellular macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.	got7fsn_ti	cellular macromolecule biosynthesis|cellular macromolecule formation|cellular macromolecule anabolism|cellular biopolymer biosynthetic process|cellular macromolecule synthesis										GO:0034961			biological_process											owl:Class	
GO:0009059	biolink:NamedThing	macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti	biopolymer biosynthetic process|macromolecule biosynthesis|macromolecule synthesis|macromolecule anabolism|macromolecule formation										GO:0043284			biological_process											owl:Class	
GO:0008719	biolink:NamedThing	dihydroneopterin triphosphate 2'-epimerase activity	Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate.	got7fsn_ti	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase activity											EC:5.1.99.7|MetaCyc:H2NTPEPIM-RXN|RHEA:28346		molecular_function											owl:Class	
GO:0090724	biolink:NamedThing	central region of growth cone	The center of the migrating motile tip of a growing nerve cell axon or dendrite.	got7fsn_ti							tb	2016-11-18T12:44:25Z						cellular_component											owl:Class	
GO:0103078	biolink:NamedThing	quercetin 3-rhamnoside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: H+ + quercetin 3-O-rhamnoside + UDP-L-rhamnose <=> quercetin-3-rhamnoside-7-rhamnoside + UDP.	got7fsn_ti												RHEA:61184|MetaCyc:RXNQT-4162		molecular_function											owl:Class	
GO:0000412	biolink:NamedThing	histone peptidyl-prolyl isomerization	The modification of a histone by cis-trans isomerization of a proline residue.	got7fsn_ti	histone proline isomerization													biological_process											owl:Class	
GO:0034359	biolink:NamedThing	mature chylomicron	A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph.	got7fsn_ti														cellular_component											owl:Class	
GO:0042627	biolink:NamedThing	chylomicron	A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.	got7fsn_ti												Wikipedia:Chylomicron		cellular_component											owl:Class	
GO:0031805	biolink:NamedThing	type 8 metabotropic glutamate receptor binding	Binding to a type 8 metabotropic glutamate receptor.	got7fsn_ti	type 8 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0047717	biolink:NamedThing	imidazoleacetate 4-monooxygenase activity	Catalysis of the reaction: H(+) + imidazol-4-ylacetate + NADH + O(2) = 5-hydroxyimidazole-4-acetate + H(2)O + NAD(+).	got7fsn_ti	4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)|imidazoleacetic hydroxylase activity|imidazoleacetic monooxygenase activity|imidazoleacetate hydroxylase activity											KEGG_REACTION:R04066|RHEA:19425|MetaCyc:IMIDAZOLEACETATE-4-MONOOXYGENASE-RXN|EC:1.14.13.5		molecular_function											owl:Class	
GO:0052833	biolink:NamedThing	inositol monophosphate 4-phosphatase activity	Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate.	got7fsn_ti	inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity						ai	2011-11-29T11:02:15Z				RHEA:30735|Reactome:R-HSA-1855211|MetaCyc:RXN-10952|EC:3.1.3.25		molecular_function											owl:Class	
GO:0052834	biolink:NamedThing	inositol monophosphate phosphatase activity	Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate.	got7fsn_ti	inositol-phosphate phosphatase activity|myo-inositol-phosphatase activity|inositol phosphatase activity|inositol-1(or 4)-monophosphatase activity|myo-inositol phosphatase activity|L-myo-inositol-phosphate phosphatase activity|myo-inositol-phosphate phosphohydrolase activity|myo-inositol monophosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity						ai	2011-11-29T11:15:58Z				EC:3.1.3.25|RHEA:24056|MetaCyc:RXN-10949		molecular_function											owl:Class	
GO:0035372	biolink:NamedThing	protein localization to microtubule	A process in which a protein is transported to, or maintained at, a microtubule.	got7fsn_ti	protein localisation to microtubule						bf	2010-03-11T11:00:56Z						biological_process											owl:Class	
GO:0072698	biolink:NamedThing	protein localization to microtubule cytoskeleton	A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.	got7fsn_ti	protein localisation to microtubule cytoskeleton						mah	2012-04-11T01:19:35Z						biological_process											owl:Class	
GO:0021853	biolink:NamedThing	cerebral cortex GABAergic interneuron migration	The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0021830	biolink:NamedThing	interneuron migration from the subpallium to the cortex	The directed movement of interneurons from the subpallium to the cortex during forebrain development.	got7fsn_ti														biological_process											owl:Class	
GO:0014023	biolink:NamedThing	neural rod formation	The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.	got7fsn_ti														biological_process											owl:Class	
GO:0097665	biolink:NamedThing	SCF-Mdm30 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae.	got7fsn_ti							pr	2014-10-06T10:27:30Z						cellular_component											owl:Class	
GO:1901511	biolink:NamedThing	(-)-microperfuranone catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone.	got7fsn_ti	(-)-microperfuranone catabolism|(-)-microperfuranone degradation|(-)-microperfuranone breakdown						di	2012-10-18T06:54:14Z						biological_process											owl:Class	
GO:1901502	biolink:NamedThing	ether catabolic process	The chemical reactions and pathways resulting in the breakdown of ether.	got7fsn_ti	ether breakdown|ether degradation|ether catabolism						pr	2012-10-17T09:42:43Z						biological_process											owl:Class	
GO:0035477	biolink:NamedThing	regulation of angioblast cell migration involved in selective angioblast sprouting	Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting.	got7fsn_ti							bf	2010-04-23T10:08:28Z						biological_process											owl:Class	
GO:1901342	biolink:NamedThing	regulation of vasculature development	Any process that modulates the frequency, rate or extent of vasculature development.	got7fsn_ti	regulation of vascular system development						bf	2012-09-06T09:16:15Z						biological_process											owl:Class	
GO:0018039	biolink:NamedThing	C-terminal peptidyl-glutamine amidation	The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0086		biological_process											owl:Class	
GO:0018199	biolink:NamedThing	peptidyl-glutamine modification	The modification of peptidyl-glutamine.	got7fsn_ti														biological_process											owl:Class	
GO:0050362	biolink:NamedThing	L-tryptophan:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate.	got7fsn_ti	tryptophan aminotransferase activity|L-tryptophan transaminase activity|tryptophan transaminase activity|hydroxytryptophan aminotransferase activity|L-phenylalanine-2-oxoglutarate aminotransferase activity|L-tryptophan aminotransferase activity|5-hydroxytryptophan-ketoglutaric transaminase activity											MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN|RHEA:14093|EC:2.6.1.27		molecular_function											owl:Class	
GO:0120136	biolink:NamedThing	dUMP kinase activity	Catalysis of the reaction: ATP + dUMP = ADP + dUDP.	got7fsn_ti	dUMP-kinase activity|ATP:dUMP phosphotransferase activity|deoxyuridine monophosphate kinase activity						krc	2018-03-21T21:16:06Z				RHEA:30655		molecular_function											owl:Class	
GO:0018655	biolink:NamedThing	2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity	Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0430|EC:1.14.13.-		molecular_function											owl:Class	
GO:0004771	biolink:NamedThing	sterol esterase activity	Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid.	got7fsn_ti	acylcholesterol lipase activity|cholesteryl ester hydrolase activity|cholesterol esterase activity|cholesterol ester synthase activity|cholesterase activity|cholesterol ester hydrolase activity|cholesteryl esterase activity|triterpenol esterase activity|sterol ester hydrolase activity|steryl-ester acylhydrolase activity|cholesteryl ester synthase activity											EC:3.1.1.13|RHEA:10100|Reactome:R-HSA-6813720|Reactome:R-HSA-8865667|Reactome:R-HSA-192417|MetaCyc:STEROL-ESTERASE-RXN		molecular_function											owl:Class	
GO:0007280	biolink:NamedThing	pole cell migration	The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form.	got7fsn_ti					See also the Cell Ontology term 'pole cell ; CL:0000301'.									biological_process											owl:Class	
GO:0008354	biolink:NamedThing	germ cell migration	The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.	got7fsn_ti	primordial germ cell migration|germ-cell migration													biological_process											owl:Class	
GO:0031316	biolink:NamedThing	extrinsic component of nuclear outer membrane	The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to nuclear outer membrane													cellular_component											owl:Class	
GO:0048709	biolink:NamedThing	oligodendrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0010001	biolink:NamedThing	glial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.	got7fsn_ti	neuroglia differentiation|glia cell differentiation										GO:0043360|GO:0007404			biological_process											owl:Class	
GO:0071185	biolink:NamedThing	protocadherin-alpha-v4-protocadherin-gamma-a3 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti	Pcdhga1-Pcdhga3 complex						mah	2009-11-23T04:16:47Z						cellular_component											owl:Class	
GO:0071183	biolink:NamedThing	protocadherin-alpha-protocadherin-gamma complex	A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti							mah	2009-11-23T04:10:30Z						cellular_component											owl:Class	
GO:0004609	biolink:NamedThing	phosphatidylserine decarboxylase activity	Catalysis of the reaction: H(+) + phosphatidyl-L-serine = CO(2) + phosphatidylethanolamine.	got7fsn_ti	PS decarboxylase activity|phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)|phosphatidyl-L-serine carboxy-lyase activity											Reactome:R-HSA-1483212|RHEA:20828|EC:4.1.1.65|KEGG_REACTION:R02055|MetaCyc:PHOSPHASERDECARB-RXN		molecular_function											owl:Class	
GO:0120120	biolink:NamedThing	bilobe structure	A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).	got7fsn_ti	kinetoplastid flagellar hook complex				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use.		krc	2017-12-11T23:47:20Z						cellular_component											owl:Class	
GO:0120197	biolink:NamedThing	mucociliary clearance	The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways.	got7fsn_ti	MCT|MCC|mucociliary transport						krc	2019-04-26T16:16:50Z						biological_process											owl:Class	
GO:0003351	biolink:NamedThing	epithelial cilium movement involved in extracellular fluid movement	The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid.	got7fsn_ti	cilium movement involved in fluid flow|epithelial cilium beating						dph	2009-12-03T10:08:25Z						biological_process											owl:Class	
GO:0042390	biolink:NamedThing	gibberellic acid mediated signaling pathway, G-alpha-independent	A series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.	got7fsn_ti	gibberellic acid mediated signalling, G-alpha-independent													biological_process											owl:Class	
GO:0009740	biolink:NamedThing	gibberellic acid mediated signaling pathway	A series of molecular signals mediated by the detection of gibberellic acid.	got7fsn_ti	GA-signaling|gibberellic acid signaling|gibberellic acid mediated signalling													biological_process											owl:Class	
GO:0048717	biolink:NamedThing	anterior cibarial plate morphogenesis	The process in which the anatomical structures of the anterior cibarial plate are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:1990403	biolink:NamedThing	embryonic brain development	The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.	got7fsn_ti							sl	2014-06-23T20:57:13Z						biological_process											owl:Class	
GO:0018204	biolink:NamedThing	peptidyl-leucine modification	The modification of peptidyl-leucine.	got7fsn_ti														biological_process											owl:Class	
GO:0018193	biolink:NamedThing	peptidyl-amino acid modification	The alteration of an amino acid residue in a peptide.	got7fsn_ti														biological_process											owl:Class	
GO:0046355	biolink:NamedThing	mannan catabolic process	The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.	got7fsn_ti	mannan degradation|mannan catabolism|mannan breakdown													biological_process											owl:Class	
GO:0044247	biolink:NamedThing	cellular polysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells.	got7fsn_ti	cellular polysaccharide degradation|cellular polysaccharide catabolism|cellular polysaccharide breakdown													biological_process											owl:Class	
GO:0052334	biolink:NamedThing	modification by organism of cytoskeleton of other organism involved in symbiotic interaction	The process in which an organism effects a change in the structure or function of the cytoskeleton of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modification by organism of cytoskeleton of other organism during symbiotic interaction													biological_process											owl:Class	
GO:0052188	biolink:NamedThing	modification of cellular component in other organism involved in symbiotic interaction	The process in which an organism effects a change in the structure or function of a cellular component in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modification of cellular component in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0035933	biolink:NamedThing	glucocorticoid secretion	The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.	got7fsn_ti							bf	2011-07-20T01:08:37Z						biological_process											owl:Class	
GO:0035930	biolink:NamedThing	corticosteroid hormone secretion	The regulated release of any corticosteroid hormone into the circulatory system.	got7fsn_ti	corticosteroid secretion						bf	2011-07-20T01:03:22Z						biological_process											owl:Class	
GO:0072261	biolink:NamedThing	metanephric extraglomerular mesangial cell proliferation involved in metanephros development	The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.	got7fsn_ti	metanephric lacis cell proliferation|metanephric Goormaghtigh proliferation						mah	2010-03-30T02:14:17Z						biological_process											owl:Class	
GO:0072122	biolink:NamedThing	extraglomerular mesangial cell proliferation	The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.	got7fsn_ti	Goormaghtigh proliferation|lacis cell proliferation						mah	2010-02-22T01:42:23Z						biological_process											owl:Class	
GO:0016445	biolink:NamedThing	somatic diversification of immunoglobulins	The somatic process that results in the generation of sequence diversity of immunoglobulins.	got7fsn_ti	somatic diversification of antibodies													biological_process											owl:Class	
GO:0002200	biolink:NamedThing	somatic diversification of immune receptors	The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.	got7fsn_ti					Note that this process covers somatic recombination, gene conversion, hypermutation, N-region addition, and alternate splicing processes of immune receptor diversification.									biological_process											owl:Class	
GO:0033758	biolink:NamedThing	clavaminate synthase activity	Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O.	got7fsn_ti	clavaminate synthase 2 activity|clavaminic acid synthase activity|deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity											RHEA:20021|EC:1.14.11.21|MetaCyc:1.14.11.21-RXN		molecular_function											owl:Class	
GO:0061055	biolink:NamedThing	myotome development	The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.	got7fsn_ti							dph	2010-03-02T12:11:01Z						biological_process											owl:Class	
GO:1901343	biolink:NamedThing	negative regulation of vasculature development	Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.	got7fsn_ti	inhibition of vasculature development|down regulation of vasculature development|downregulation of vasculature development|inhibition of vascular system development|downregulation of vascular system development|down regulation of vascular system development|down-regulation of vascular system development|down-regulation of vasculature development|negative regulation of vascular system development						bf	2012-09-06T09:17:24Z						biological_process											owl:Class	
GO:0000238	biolink:NamedThing	zygotene	The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Meiosis#Zygotene|Wikipedia:Zygotene		biological_process											owl:Class	
GO:0098764	biolink:NamedThing	meiosis I cell cycle phase	A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0050633	biolink:NamedThing	acetyl-CoA C-myristoyltransferase activity	Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.	got7fsn_ti	myristoyl-CoA C-acetyltransferase activity|3-oxopalmitoyl-CoA hydrolase activity|3-oxopalmitoyl-CoA-CoA acetyltransferase activity|myristoyl-CoA:acetyl-CoA C-myristoyltransferase activity											MetaCyc:2.3.1.155-RXN|RHEA:18161|EC:2.3.1.155		molecular_function											owl:Class	
GO:0016408	biolink:NamedThing	C-acyltransferase activity	Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0031522	biolink:NamedThing	cell envelope Sec protein transport complex	A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.	got7fsn_ti	Sec translocation complex|Sec complex|Sec secretion complex|plasma membrane Sec complex				Note that this term represents the protein complex involved in transport of proteins across the cytoplasmic membrane. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'type II protein secretion complex ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'endoplasmic reticulum Sec complex ; GO:0031205'.									cellular_component											owl:Class	
GO:0030258	biolink:NamedThing	lipid modification	The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.	got7fsn_ti														biological_process											owl:Class	
GO:0006506	biolink:NamedThing	GPI anchor biosynthetic process	The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.	got7fsn_ti	glycosylphosphatidylinositol biosynthetic process|GPI anchor biosynthesis|GPI anchor formation|glycosylphosphatidylinositol biosynthesis|GPI anchor anabolism|GPI/GSI anchor biosynthesis|GPI/GSI anchor biosynthetic process|GPI anchor synthesis										GO:0015998			biological_process											owl:Class	
GO:0006497	biolink:NamedThing	protein lipidation	The covalent attachment of lipid groups to an amino acid in a protein.	got7fsn_ti	protein amino acid lipidation|lipid:protein modification				For non-covalent interactions with a lipid, consider instead the term 'lipid binding ; GO:0008289' and its children.						GO:0042050	RESID:AA0104|RESID:AA0159|RESID:AA0078|RESID:AA0162|RESID:AA0080|RESID:AA0106|RESID:AA0158|RESID:AA0060|RESID:AA0079|RESID:AA0307|RESID:AA0077|RESID:AA0309|RESID:AA0102|RESID:AA0308|RESID:AA0059|RESID:AA0163|RESID:AA0160|RESID:AA0161|RESID:AA0103|RESID:AA0107|RESID:AA0316|RESID:AA0166|RESID:AA0290|RESID:AA0223		biological_process											owl:Class	
GO:0003425	biolink:NamedThing	establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division	A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate.	got7fsn_ti							dph	2009-12-22T10:36:36Z						biological_process											owl:Class	
GO:0090176	biolink:NamedThing	microtubule cytoskeleton organization involved in establishment of planar polarity	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity.	got7fsn_ti	microtubule cytoskeleton organisation involved in establishment of planar polarity						tb	2009-12-14T10:34:25Z						biological_process											owl:Class	
GO:0047649	biolink:NamedThing	alkylglycerol kinase activity	Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H(+).	got7fsn_ti	1-alkylglycerol kinase (phosphorylating)|alkylglycerol phosphotransferase activity|ATP:1-alkyl-sn-glycerol phosphotransferase activity|ATP-alkylglycerol phosphotransferase activity|ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase activity											MetaCyc:ALKYLGLYCEROL-KINASE-RXN|EC:2.7.1.93|KEGG_REACTION:R04126|RHEA:16937		molecular_function											owl:Class	
GO:0050578	biolink:NamedThing	(R)-2-hydroxyacid dehydrogenase activity	Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+.	got7fsn_ti	L-sulfolactate dehydrogenase activity|(R)-sulfolactate:NAD(P)(+) oxidoreductase activity|(R)-sulfolactate:NAD(P)+ oxidoreductase activity|(R)-2-hydroxyacid:NAD(P)+ oxidoreductase activity											RHEA:35735|MetaCyc:1.1.1.272-RXN|EC:1.1.1.272		molecular_function											owl:Class	
GO:0000746	biolink:NamedThing	conjugation	The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.	got7fsn_ti												Wikipedia:Conjugation		biological_process											owl:Class	
GO:0044764	biolink:NamedThing	multi-organism cellular process	Any process that is carried out at the cellular level which involves another organism of the same or different species.	got7fsn_ti							jl	2012-12-11T17:00:50Z						biological_process											owl:Class	
GO:0097345	biolink:NamedThing	mitochondrial outer membrane permeabilization	The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.	got7fsn_ti	mitochondrial outer membrane permeabilization during apoptotic cell death|mitochondrion outer membrane permeabilization|MOMP|mitochondrial outer membrane permeabilization				BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).		pr	2012-06-19T04:06:54Z						biological_process											owl:Class	
GO:1902110	biolink:NamedThing	positive regulation of mitochondrial membrane permeability involved in apoptotic process	Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.	got7fsn_ti	positive regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|positive regulation of transport across mitochondrial membrane involved in type I programmed cell death|mitochondrial membrane permeability transition involved in type I programmed cell death|positive regulation of mitochondrial membrane permeability involved in apoptotic cell death|positive regulation of transport across mitochondrial membrane involved in apoptotic cell death|mitochondrial permeability transition involved in apoptotic cell death|mitochondrial permeability transition involved in apoptosis|mitochondrial membrane permeabilization involved in apoptotic programmed cell death|mitochondrial membrane permeability transition involved in apoptotic process|mitochondrial membrane permeabilization involved in signaling (initiator) caspase activity|mitochondrial permeability transition involved in apoptotic programmed cell death|mitochondrial membrane permeabilization involved in apoptotic process|positive regulation of mitochondrial membrane permeability involved in apoptotic program|positive regulation of transport across mitochondrial membrane involved in apoptotic program|positive regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|mitochondrial permeability transition involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in apoptotic cell death|mitochondrial membrane permeabilization involved in programmed cell death by apoptosis|positive regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|mitochondrial permeability transition involved in type I programmed cell death|positive regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in apoptosis|mitochondrial membrane permeability transition involved in programmed cell death by apoptosis|positive regulation of transport across mitochondrial membrane involved in apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptosis|mitochondrial permeability transition involved in apoptotic program|positive regulation of transport across mitochondrial membrane involved in apoptotic process|mitochondrial membrane permeabilization involved in type I programmed cell death|mitochondrial permeability transition involved in programmed cell death by apoptosis|mitochondrial membrane permeabilization involved in apoptotic program|mitochondrial membrane permeability transition involved in apoptotic program|mitochondrial membrane permeabilization involved in apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in type I programmed cell death|mitochondrial permeability transition involved in apoptotic process|mitochondrial membrane permeabilization involved in apoptotic cell death|mitochondrial membrane permeability transition involved in apoptotic programmed cell death				Individual components of the mitochondrial permeability transition pore complex, such as the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D), are involved in this process.		pr	2013-05-03T12:13:56Z						biological_process											owl:Class	
GO:0033277	biolink:NamedThing	abortive mitotic cell cycle	A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy.	got7fsn_ti	abortive mitosis				Note that this term should be used only for abortive mitotic events that occur normally, e.g. during megakaryocyte differentiation; it should not be used for incomplete mitosis resulting from mutation or other abnormal occurrences. Note that this term should not be confused with 'endomitotic cell cycle ; GO:0007113', which describes a process in which no mitotic spindle forms.									biological_process											owl:Class	
GO:0000278	biolink:NamedThing	mitotic cell cycle	Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.	got7fsn_ti	mitosis				Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.						GO:0007067	Wikipedia:Mitosis		biological_process											owl:Class	
GO:0000721	biolink:NamedThing	(R,R)-butanediol dehydrogenase activity	Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H(+).	got7fsn_ti	2,3-butanediol dehydrogenase activity|1-amino-2-propanol dehydrogenase activity|butyleneglycol dehydrogenase activity|1-amino-2-propanol oxidoreductase activity|D-1-amino-2-propanol:NAD(2) oxidoreductase activity|(R)-diacetyl reductase activity|D-aminopropanol dehydrogenase activity|D-butanediol dehydrogenase activity|D-(-)-butanediol dehydrogenase activity|aminopropanol oxidoreductase activity|butylene glycol dehydrogenase activity|D-1-amino-2-propanol dehydrogenase activity|diacetyl (acetoin) reductase activity|(R)-2,3-butanediol dehydrogenase activity											MetaCyc:RR-BUTANEDIOL-DEHYDROGENASE-RXN|EC:1.1.1.4|RHEA:24340		molecular_function											owl:Class	
GO:0047175	biolink:NamedThing	galactosylacylglycerol O-acyltransferase activity	Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein].	got7fsn_ti	acyl-acyl-carrier-protein:D-galactosylacylglycerol O-acyltransferase activity|acyl-ACP:lyso-MGDG acyltransferase activity|acyl-acyl-carrier protein: lysomonogalactosyldiacylglycerol acyltransferase activity											RHEA:17057|MetaCyc:2.3.1.141-RXN|EC:2.3.1.141		molecular_function											owl:Class	
GO:0036481	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to hydrogen peroxide	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2).	got7fsn_ti	hydrogen peroxide-induced apoptosis|H2O2-induced intrinsic apoptotic signaling pathway|hydrogen peroxide-induced intrinsic apoptotic signaling pathway|intrinsic apoptotic signaling pathway in response to H2O2						bf	2014-08-14T13:19:21Z						biological_process											owl:Class	
GO:0008631	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to oxidative stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	oxidative stress-induced intrinsic apoptotic signaling pathway|induction of apoptosis by oxidative stress													biological_process											owl:Class	
GO:0009510	biolink:NamedThing	plasmodesmatal desmotubule	A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell.	got7fsn_ti	desmotubule central rod										GO:0009572			cellular_component											owl:Class	
GO:0034969	biolink:NamedThing	histone arginine methylation	The modification of a histone by addition of a methyl group to an arginine residue.	got7fsn_ti														biological_process											owl:Class	
GO:0016571	biolink:NamedThing	histone methylation	The modification of histones by addition of methyl groups.	got7fsn_ti												Wikipedia:Histone_methylation		biological_process											owl:Class	
GO:0140536	biolink:NamedThing	nuclear receptor corepressor activity	A transcription corepressor activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Nuclear receptor corepressors often act by altering chromatin structure and modifications. For example, one class of transcription nuclear receptor corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.	got7fsn_ti	nuclear corepressor activity	https://github.com/geneontology/go-ontology/issues/20262|https://github.com/geneontology/go-ontology/issues/20464			For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.		pg	2020-11-03T13:02:08Z						molecular_function											owl:Class	
GO:0003714	biolink:NamedThing	transcription corepressor activity	A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.	got7fsn_ti	RNA polymerase II transcription corepressor activity|transcription corepressor activity|RNA polymerase II transcription co-repressor activity|transcription co-repressor activity	https://github.com/geneontology/go-ontology/issues/20464|https://github.com/geneontology/go-ontology/issues/15665|https://github.com/geneontology/go-ontology/issues/15998			For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.		krc	2010-11-24T03:14:44Z			GO:0001106			molecular_function											owl:Class	
GO:0050402	biolink:NamedThing	xylono-1,4-lactonase activity	Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate.	got7fsn_ti	xylonolactonase activity|xylono-g-lactonase activity|D-xylono-1,4-lactone lactonohydrolase activity											RHEA:18341|EC:3.1.1.68|MetaCyc:XYLONO-14-LACTONASE-RXN		molecular_function											owl:Class	
GO:0060919	biolink:NamedThing	auxin influx	The process involved in the transport of auxin into the cell.	got7fsn_ti							dph	2009-09-28T02:49:18Z						biological_process											owl:Class	
GO:0060918	biolink:NamedThing	auxin transport	The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							dph	2009-09-28T02:44:54Z						biological_process											owl:Class	
GO:0021905	biolink:NamedThing	forebrain-midbrain boundary formation	The process whose specific outcome is the creation of the forebrain-midbrain boundary.	got7fsn_ti														biological_process											owl:Class	
GO:0009308	biolink:NamedThing	amine metabolic process	The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.	got7fsn_ti	amine metabolism													biological_process											owl:Class	
GO:0010411	biolink:NamedThing	xyloglucan metabolic process	The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.	got7fsn_ti	xyloglucan metabolism													biological_process											owl:Class	
GO:0006073	biolink:NamedThing	cellular glucan metabolic process	The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell.	got7fsn_ti	cellular glucan metabolism													biological_process											owl:Class	
GO:0052720	biolink:NamedThing	class II DNA-(apurinic or apyrimidinic site) endonuclease activity	Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	got7fsn_ti	class II DNA-(apurinic or apyrimidinic site) lyase activity	https://github.com/geneontology/go-ontology/issues/13409			Class II AP endonuclease is a nuclease, but not Class I, III and IV.		pg	2017-07-24T11:46:03Z			GO:0140079			molecular_function											owl:Class	
GO:0003906	biolink:NamedThing	DNA-(apurinic or apyrimidinic site) endonuclease activity	Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).	got7fsn_ti	apyrimidinic deoxyendoribonuclease activity|abasic deoxyendoribonuclease activity|deoxyribonuclease (apurinic or apyrimidinic) activity|AP deoxyendoribonuclease activity|UV endonuclease|apurinic deoxyendoribonuclease activity|apurinic/apyrimidinic endodeoxyribonuclease activity|endonuclease VIII activity											Reactome:R-HSA-5649725|Reactome:R-HSA-5649711|Reactome:R-HSA-110375		molecular_function											owl:Class	
GO:0005587	biolink:NamedThing	collagen type IV trimer	A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.	got7fsn_ti												Wikipedia:Collagen_type_IV		cellular_component											owl:Class	
GO:0098642	biolink:NamedThing	network-forming collagen trimer	A collagen trimer that forms networks.	got7fsn_ti														cellular_component											owl:Class	
GO:0070381	biolink:NamedThing	endosome to plasma membrane transport vesicle	A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane  and to release various cargo molecules, such as proteins or hormones, by exocytosis.	got7fsn_ti	endosome to plasma membrane constitutive secretory pathway transport vesicle|endosome-plasma membrane transport vesicle													cellular_component											owl:Class	
GO:0070382	biolink:NamedThing	exocytic vesicle	A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.	got7fsn_ti	exocytic constitutive secretory pathway transport vesicle|exocytotic vesicle													cellular_component											owl:Class	
GO:0003217	biolink:NamedThing	cardiac right atrium formation	The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.	got7fsn_ti							dph	2009-10-13T09:53:12Z						biological_process											owl:Class	
GO:0003210	biolink:NamedThing	cardiac atrium formation	The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.	got7fsn_ti							dph	2009-10-13T09:44:25Z						biological_process											owl:Class	
GO:0080086	biolink:NamedThing	stamen filament development	The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen.	got7fsn_ti	filament development						dhl	2009-04-22T03:12:03Z						biological_process											owl:Class	
GO:0042543	biolink:NamedThing	protein N-linked glycosylation via arginine	The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine.	got7fsn_ti	protein amino acid N-linked glycosylation via arginine											RESID:AA0327		biological_process											owl:Class	
GO:0018195	biolink:NamedThing	peptidyl-arginine modification	The modification of peptidyl-arginine.	got7fsn_ti														biological_process											owl:Class	
GO:1990424	biolink:NamedThing	protein arginine kinase activity	Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate.	got7fsn_ti					This reaction occurs in bacterial species e.g. Bacillus subtilis.		jl	2014-07-23T13:35:56Z						molecular_function											owl:Class	
GO:0004672	biolink:NamedThing	protein kinase activity	Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.	got7fsn_ti	protamine kinase activity				Note that triphosphate is used as a phosphate donor by at least one kinase.						GO:0050222	MetaCyc:PROTEIN-KINASE-RXN|Reactome:R-HSA-937034|Reactome:R-HSA-9604606|Reactome:R-HSA-9673284|Reactome:R-HSA-156832|Reactome:R-HSA-975139		molecular_function											owl:Class	
GO:0070427	biolink:NamedThing	nucleotide-binding oligomerization domain containing 1 signaling pathway	Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1).	got7fsn_ti	nucleotide-binding oligomerization domain containing 1 signalling pathway|NOD1 signaling pathway													biological_process											owl:Class	
GO:0070423	biolink:NamedThing	nucleotide-binding oligomerization domain containing signaling pathway	Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.	got7fsn_ti	NOD signaling pathway|nucleotide-binding oligomerization domain containing signalling pathway													biological_process											owl:Class	
GO:0003022	biolink:NamedThing	detection of pH by chemoreceptor signaling	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.	got7fsn_ti	detection of pH by chemoreceptor signalling													biological_process											owl:Class	
GO:0003030	biolink:NamedThing	detection of hydrogen ion	The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:1990431	biolink:NamedThing	priRNA 3'-end processing	The process of forming the mature 3' end of a priRNA molecule.	got7fsn_ti	primal small RNA 3'-end processing|priRNA 3' end processing						jl	2014-07-29T15:34:19Z						biological_process											owl:Class	
GO:0043628	biolink:NamedThing	ncRNA 3'-end processing	Any process involved in forming the mature 3' end of a non-coding RNA molecule.	got7fsn_ti	ncRNA 3' end processing													biological_process											owl:Class	
GO:0016580	biolink:NamedThing	Sin3 complex	A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0070822	biolink:NamedThing	Sin3-type complex	Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.	got7fsn_ti							mah	2009-07-20T04:32:33Z						cellular_component											owl:Class	
GO:0046455	biolink:NamedThing	organosilicon catabolic process	The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon.	got7fsn_ti	organosilicon catabolism|organosilicon degradation|organosilicone catabolic process|organosilicone catabolism|organosilicon breakdown													biological_process											owl:Class	
GO:0042178	biolink:NamedThing	xenobiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	exogenous drug catabolic process|drug catabolic process|exogenous drug catabolism|exogenous drug breakdown|drug degradation|drug catabolism|xenobiotic degradation|drug breakdown|exogenous drug degradation|xenobiotic breakdown|xenobiotic catabolism	https://github.com/geneontology/go-ontology/issues/19460									GO:0042737|GO:0042738			biological_process											owl:Class	
GO:0035082	biolink:NamedThing	axoneme assembly	The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.	got7fsn_ti	ciliary axoneme assembly|flagellar axoneme assembly|cilium axoneme assembly|axoneme biogenesis|cilium axoneme biogenesis|flagellum axoneme assembly				Note that cilia and eukaryotic flagella are deemed to be equivalent.						GO:0035083|GO:0035084			biological_process											owl:Class	
GO:0001578	biolink:NamedThing	microtubule bundle formation	A process that results in a parallel arrangement of microtubules.	got7fsn_ti	microtubule bundling													biological_process											owl:Class	
GO:0043209	biolink:NamedThing	myelin sheath	An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.	got7fsn_ti	astrocyte sheath|Schwann cell myelin sheath|oligodendrocyte myelin sheath											NIF_Subcellular:sao593830697|FMA:62983|Wikipedia:Myelin		cellular_component											owl:Class	
GO:0043367	biolink:NamedThing	CD4-positive, alpha-beta T cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.	got7fsn_ti	CD4-positive, alpha-beta T-cell differentiation|CD4-positive, alpha-beta T lymphocyte differentiation|CD4-positive, alpha beta T cell development|CD4-positive, alpha-beta T-lymphocyte differentiation|CD4-positive, alpha beta T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0035710	biolink:NamedThing	CD4-positive, alpha-beta T cell activation	The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti							bf	2011-03-02T03:04:11Z						biological_process											owl:Class	
GO:0051881	biolink:NamedThing	regulation of mitochondrial membrane potential	Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0008024	biolink:NamedThing	cyclin/CDK positive transcription elongation factor complex	A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit.	got7fsn_ti	positive transcription elongation factor complex b				See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.									cellular_component											owl:Class	
GO:0032806	biolink:NamedThing	carboxy-terminal domain protein kinase complex	A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.	got7fsn_ti	CTDK complex													cellular_component											owl:Class	
GO:0047349	biolink:NamedThing	D-ribitol-5-phosphate cytidylyltransferase activity	Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate.	got7fsn_ti	CTP:D-ribitol-5-phosphate cytidylyltransferase activity|ribitol 5-phosphate cytidylyltransferase activity|cytidine diphosphoribitol pyrophosphorylase activity|CDP-ribitol diphosphorylase activity|CDP ribitol pyrophosphorylase activity|CDP-ribitol pyrophosphorylase activity|cytidine diphosphate ribitol pyrophosphorylase activity											KEGG_REACTION:R02921|EC:2.7.7.40|RHEA:12456|MetaCyc:2.7.7.40-RXN		molecular_function											owl:Class	
GO:0070567	biolink:NamedThing	cytidylyltransferase activity	Catalysis of the transfer of a cytidylyl group to an acceptor.	got7fsn_ti							mah	2009-04-15T11:05:22Z						molecular_function											owl:Class	
GO:0072038	biolink:NamedThing	mesenchymal stem cell maintenance involved in nephron morphogenesis	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti							mah	2010-01-25T03:08:05Z						biological_process											owl:Class	
GO:0035019	biolink:NamedThing	somatic stem cell population maintenance	Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.	got7fsn_ti														biological_process											owl:Class	
GO:0061771	biolink:NamedThing	response to caloric restriction	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake.	got7fsn_ti							dph	2016-07-09T09:40:32Z						biological_process											owl:Class	
GO:0006950	biolink:NamedThing	response to stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti	response to biotic stress|response to abiotic stress				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0008544	biolink:NamedThing	epidermis development	The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.	got7fsn_ti	hypodermis development													biological_process											owl:Class	
GO:0009888	biolink:NamedThing	tissue development	The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.	got7fsn_ti	histogenesis|histogenesis and organogenesis											Wikipedia:Histogenesis		biological_process											owl:Class	
GO:0036409	biolink:NamedThing	histone H3-K14 acetyltransferase complex	A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3.	got7fsn_ti	histone acetyltransferase complex (H3-K14 specific)|histone H3 Lys 14 (H3K14) acetyltransferase complex|H3-K14 histone acetyltransferase complex|histone H3K14 acetyltransferase complex						bf	2013-08-21T10:06:34Z						cellular_component											owl:Class	
GO:0070775	biolink:NamedThing	H3 histone acetyltransferase complex	A multisubunit complex that catalyzes the acetylation of histone H3.	got7fsn_ti	H3 HAT complex						mah	2009-07-02T11:56:48Z						cellular_component											owl:Class	
GO:0015013	biolink:NamedThing	heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide	The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan.	got7fsn_ti	heparan sulfate proteoglycan synthesis, linkage to polypeptide|heparin proteoglycan biosynthetic process, linkage to polypeptide|heparan sulphate proteoglycan biosynthetic process, linkage to polypeptide|heparan sulfate proteoglycan formation, linkage to polypeptide|heparan sulfate proteoglycan anabolism, linkage to polypeptide|heparan sulphate proteoglycan biosynthesis, linkage to polypeptide													biological_process											owl:Class	
GO:0018242	biolink:NamedThing	protein O-linked glycosylation via serine	The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine.	got7fsn_ti	protein amino acid O-linked glycosylation via serine											RESID:AA0154		biological_process											owl:Class	
GO:0035568	biolink:NamedThing	N-terminal peptidyl-proline methylation	The methylation of the N-terminal proline of proteins.	got7fsn_ti							bf	2010-08-06T01:52:43Z				RESID:AA0419		biological_process											owl:Class	
GO:0006480	biolink:NamedThing	N-terminal protein amino acid methylation	The methylation of the N-terminal amino acid of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0071914	biolink:NamedThing	prominosome	An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.	got7fsn_ti	prominin-containing extracellular membrane vesicle						mah	2010-09-24T09:24:36Z						cellular_component											owl:Class	
GO:1903561	biolink:NamedThing	extracellular vesicle	Any vesicle that is part of the extracellular region.	got7fsn_ti	microparticle						jl	2014-10-22T14:26:11Z						cellular_component											owl:Class	
GO:0099000	biolink:NamedThing	viral genome ejection through host cell envelope, contractile tail mechanism	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath.   Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope.	got7fsn_ti	viral contractile tail ejection system											VZ:3950		biological_process											owl:Class	
GO:0039678	biolink:NamedThing	viral genome ejection through host cell envelope	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm.	got7fsn_ti	viral genome injection through bacterial membranes|phage genome ejection				When a pore-forming protein is involved, see also 'pore-mediated entry of viral genome into host cell ; GO:0044694'.		bf	2013-09-26T11:56:48Z						biological_process											owl:Class	
GO:0004991	biolink:NamedThing	parathyroid hormone receptor activity	Combining with parathyroid hormone to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0043494	biolink:NamedThing	CLRC complex	An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi.	got7fsn_ti	Rik1-E3 ubiquitin ligase complex|Clr4-Rik1-Cul4 complex|CLRC ubiquitin ligase complex|Rik1 E3 ubiquitin ligase complex													cellular_component											owl:Class	
GO:0031465	biolink:NamedThing	Cul4B-RING E3 ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits.	got7fsn_ti	cullin-RING ligase 4B													cellular_component											owl:Class	
GO:0015667	biolink:NamedThing	site-specific DNA-methyltransferase (cytosine-N4-specific) activity	Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.	got7fsn_ti	m4C-forming MTase activity|N(4)-cytosine-specific DNA methylase activity|N4-cytosine-specific DNA methylase activity|restriction-modification system activity|modification methylase activity|S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity|S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity|DNA[cytosine-N4]methyltransferase activity											RHEA:16857|MetaCyc:2.1.1.113-RXN|EC:2.1.1.113		molecular_function											owl:Class	
GO:1990440	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.	got7fsn_ti	ER stress-induced upregulation of transcription|up-regulation of transcription induced by ER stress|activation of transcription from RNA polymerase II promoter in response to ER stress|up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|upregulation of Pol II transcription induced by ER stress|stimulation of transcription from RNA polymerase II promoter in response to ER stress						bf	2014-07-31T12:56:54Z						biological_process											owl:Class	
GO:0036003	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to stress	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti							bf	2011-09-19T03:00:18Z						biological_process											owl:Class	
GO:1902106	biolink:NamedThing	negative regulation of leukocyte differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.	got7fsn_ti	down regulation of leukocyte differentiation|down-regulation of leukocyte differentiation|negative regulation of immune cell differentiation|inhibition of leucocyte differentiation|down regulation of immune cell differentiation|down-regulation of leucocyte differentiation|negative regulation of leucocyte differentiation|down regulation of leucocyte differentiation|downregulation of leukocyte differentiation|inhibition of leukocyte differentiation|downregulation of immune cell differentiation|inhibition of immune cell differentiation|down-regulation of immune cell differentiation|downregulation of leucocyte differentiation						pr	2013-05-02T17:32:47Z						biological_process											owl:Class	
GO:0102925	biolink:NamedThing	solanine UDP-galactose galactosyltransferase activity	Catalysis of the reaction: UDP-D-galactose + solanidine = H+ + gamma-solanine + UDP.	got7fsn_ti												MetaCyc:RXN-8875		molecular_function											owl:Class	
GO:0005277	biolink:NamedThing	acetylcholine transmembrane transporter activity	Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.	got7fsn_ti												Reactome:R-HSA-264615		molecular_function											owl:Class	
GO:0005326	biolink:NamedThing	neurotransmitter transmembrane transporter activity	Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.	got7fsn_ti	neurotransmitter transmembrane transporter activity|neurotransmitter transporter activity											Reactome:R-HSA-374919|Reactome:R-HSA-374896		molecular_function											owl:Class	
GO:0010498	biolink:NamedThing	proteasomal protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.	got7fsn_ti	proteasome-mediated protein catabolic process|proteasome-mediated protein catabolism													biological_process											owl:Class	
GO:0051603	biolink:NamedThing	proteolysis involved in cellular protein catabolic process	The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.	got7fsn_ti	peptidolysis involved in cellular protein catabolism|peptidolysis during cellular protein catabolic process|proteolysis during cellular protein catabolism|peptidolysis during cellular protein catabolism|proteolysis during cellular protein catabolic process|peptidolysis involved in cellular protein catabolic process													biological_process											owl:Class	
GO:0043100	biolink:NamedThing	pyrimidine nucleobase salvage	Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis.	got7fsn_ti	pyrimidine base salvage													biological_process											owl:Class	
GO:0008655	biolink:NamedThing	pyrimidine-containing compound salvage	Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.	got7fsn_ti	pyrimidine salvage													biological_process											owl:Class	
GO:0047533	biolink:NamedThing	2,5-dioxovalerate dehydrogenase (NADP+) activity	Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.	got7fsn_ti	2-oxoglutarate semialdehyde dehydrogenase activity|alpha-ketoglutaric semialdehyde dehydrogenase activity|2,5-dioxopentanoate:NADP+ 5-oxidoreductase activity											EC:1.2.1.26|MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN|RHEA:11296		molecular_function											owl:Class	
GO:0046176	biolink:NamedThing	aldonic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.	got7fsn_ti	aldonic acid breakdown|aldonic acid catabolism|aldonic acid degradation													biological_process											owl:Class	
GO:0044275	biolink:NamedThing	cellular carbohydrate catabolic process	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	got7fsn_ti	cellular carbohydrate degradation|cellular carbohydrate breakdown|cellular carbohydrate catabolism													biological_process											owl:Class	
GO:0047750	biolink:NamedThing	cholestenol delta-isomerase activity	Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol.	got7fsn_ti	cholestenol D-isomerase activity|delta7-cholestenol delta7-delta8-isomerase activity											RHEA:15281|EC:5.3.3.5|MetaCyc:RXN66-25		molecular_function											owl:Class	
GO:0061274	biolink:NamedThing	mesonephric distal tubule development	The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.	got7fsn_ti							dph	2010-09-02T12:16:25Z						biological_process											owl:Class	
GO:0072017	biolink:NamedThing	distal tubule development	The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.	got7fsn_ti							mah	2010-01-25T02:34:19Z						biological_process											owl:Class	
GO:0005901	biolink:NamedThing	caveola	A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis.  Caveolae may be pinched off to form free vesicles within the cytoplasm.	got7fsn_ti	caveolae|caveolar membrane										GO:0016599	Wikipedia:Caveolae		cellular_component											owl:Class	
GO:0045121	biolink:NamedThing	membrane raft	Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.	got7fsn_ti	GEM domain|glycolipid-enriched membrane domain|lipid raft											Wikipedia:Lipid_raft		cellular_component											owl:Class	
GO:0043622	biolink:NamedThing	cortical microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.	got7fsn_ti	cortical microtubule organization and biogenesis|cortical microtubule cytoskeleton organization|cortical microtubule organisation													biological_process											owl:Class	
GO:0072678	biolink:NamedThing	T cell migration	The movement of a T cell within or between different tissues and organs of the body.	got7fsn_ti	T-cell migration|T lymphocyte migration|T-lymphocyte migration						mah	2011-02-22T03:40:40Z						biological_process											owl:Class	
GO:0097201	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to stress	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti							pr	2011-12-14T09:16:22Z						biological_process											owl:Class	
GO:0043618	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to stress	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti														biological_process											owl:Class	
GO:0061433	biolink:NamedThing	cellular response to caloric restriction	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.	got7fsn_ti							dph	2012-02-09T09:03:15Z						biological_process											owl:Class	
GO:0061195	biolink:NamedThing	taste bud formation	The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.	got7fsn_ti							dph	2010-07-27T12:22:26Z						biological_process											owl:Class	
GO:0160004	biolink:NamedThing	poly-ADP-D-ribose modification-dependent protein binding	Binding to a protein upon poly-ADP-ribosylation of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require a poly-ADP-D-ribose post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the ADP-D-ribose modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		rl	2021-07-12T23:36:00Z						molecular_function											owl:Class	
GO:0160002	biolink:NamedThing	ADP-D-ribose modification-dependent protein binding	Binding to a protein upon ADP-ribosylation of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require a ADP-D-ribose post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the ADP-D-ribose modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		rl	2021-07-12T23:31:53Z						molecular_function											owl:Class	
GO:0008332	biolink:NamedThing	low voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.	got7fsn_ti	low voltage-dependent calcium channel activity|T-type calcium channel|low voltage gated calcium channel activity													molecular_function											owl:Class	
GO:0005245	biolink:NamedThing	voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	dihydropyridine-sensitive calcium channel activity|voltage gated calcium channel activity|depolarization-activated calcium channel|voltage-gated calcium ion channel activity|depolarization-activated voltage-gated calcium channel activity|depolarization-activated voltage-gated calcium channel|voltage-dependent calcium channel activity|voltage-sensitive calcium channel|depolarization-activated voltage gated calcium channel activity										GO:0010173|GO:0015270	Reactome:R-HSA-5577213|Reactome:R-HSA-265645|Reactome:R-HSA-9701055|Reactome:R-HSA-9701141		molecular_function											owl:Class	
GO:0000285	biolink:NamedThing	1-phosphatidylinositol-3-phosphate 5-kinase activity	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+).	got7fsn_ti	ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity|phosphatidylinositol-3-phosphate 5-kinase activity|phosphatidylinositol 3-phosphate 5-kinase activity|type III PIP kinase activity											Reactome:R-HSA-1676134|Reactome:R-HSA-1676168|MetaCyc:2.7.1.150-RXN|Reactome:R-HSA-1675921|KEGG_REACTION:R05802|Reactome:R-HSA-1675910|RHEA:13609|EC:2.7.1.150		molecular_function											owl:Class	
GO:0016307	biolink:NamedThing	phosphatidylinositol phosphate kinase activity	Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.	got7fsn_ti	phosphatidylinositol monophosphate kinase activity													molecular_function											owl:Class	
GO:0008269	biolink:NamedThing	JAK pathway signal transduction adaptor activity	The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way.	got7fsn_ti														molecular_function											owl:Class	
GO:0035591	biolink:NamedThing	signaling adaptor activity	The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.	got7fsn_ti	signaling scaffold activity|signalling adaptor activity	https://github.com/geneontology/go-ontology/issues/19050			A signaling adaptor can bring together both protein and non-protein molecules within a signaling pathway. Scaffold proteins act in at least four ways: tethering signaling components, localizing these components to specific areas of the cell, regulating signal transduction by coordinating positive and negative feedback signals, and insulating correct signaling proteins from competing proteins (PMID:19104498).		bf	2010-11-05T11:22:01Z						molecular_function											owl:Class	
GO:0061359	biolink:NamedThing	regulation of Wnt signaling pathway by Wnt protein secretion	Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell.	got7fsn_ti	regulation of Wnt receptor signalling pathway by Wnt protein secretion|regulation of Wnt receptor signaling pathway by Wnt protein secretion|regulation of Wnt-activated signaling pathway by Wnt protein secretion						dph	2010-10-08T01:18:02Z						biological_process											owl:Class	
GO:0030111	biolink:NamedThing	regulation of Wnt signaling pathway	Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.	got7fsn_ti	regulation of frizzled signalling pathway|regulation of Wnt-activated signaling pathway|regulation of Wnt receptor signaling pathway|regulation of frizzled signaling pathway|regulation of Wnt receptor signalling pathway										GO:0008590			biological_process											owl:Class	
GO:1990464	biolink:NamedThing	D-2-hydroxyacid dehydrogenase (quinone) activity	Catalysis of the reaction: (R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol.	got7fsn_ti	D-lactate dehydrogenase activity|(R)-2-hydroxy acid dehydrogenase activity|(R)-2-hydroxyacid:quinone oxidoreductase activity|D-lactate:quinone oxidoreductase activity|(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity|D-lactate dehydrogenase (quinone) activity				(R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors.		pr	2014-08-22T10:13:42Z						molecular_function											owl:Class	
GO:0016901	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.	got7fsn_ti												EC:1.1.5.-		molecular_function											owl:Class	
GO:0008938	biolink:NamedThing	nicotinate N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine.	got7fsn_ti	furanocoumarin 8-O-methyltransferase activity|S-adenosyl-L-methionine:nicotinate N-methyltransferase activity											EC:2.1.1.7|MetaCyc:NICOTINATE-N-METHYLTRANSFERASE-RXN|RHEA:20241|KEGG_REACTION:R01721		molecular_function											owl:Class	
GO:0070499	biolink:NamedThing	exosporium assembly	A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore.	got7fsn_ti	exosporium formation													biological_process											owl:Class	
GO:0045229	biolink:NamedThing	external encapsulating structure organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.	got7fsn_ti	external encapsulating structure organisation|external encapsulating structure organization and biogenesis													biological_process											owl:Class	
GO:0033438	biolink:NamedThing	ACC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an ACC codon.	got7fsn_ti	threonine tRNA				Note that in the standard genetic code, ACC codes for threonine.									molecular_function											owl:Class	
GO:0030142	biolink:NamedThing	COPI-coated Golgi to ER transport vesicle	A vesicle that mediates transport from the Golgi to the endoplasmic reticulum.	got7fsn_ti	Golgi to endoplasmic reticulum transport vesicle|Golgi-ER transport vesicle|Golgi-endoplasmic reticulum transport vesicle|Golgi to ER constitutive secretory pathway transport vesicle|retrograde transport vesicle													cellular_component											owl:Class	
GO:0030137	biolink:NamedThing	COPI-coated vesicle	A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport.	got7fsn_ti	coatomer													cellular_component											owl:Class	
GO:0015935	biolink:NamedThing	small ribosomal subunit	The smaller of the two subunits of a ribosome.	got7fsn_ti	ribosomal small subunit													cellular_component											owl:Class	
GO:0044391	biolink:NamedThing	ribosomal subunit	Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit.	got7fsn_ti							jl	2011-12-15T04:47:59Z						cellular_component											owl:Class	
GO:0071152	biolink:NamedThing	G-protein alpha(q)-synembrin complex	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein.	got7fsn_ti	Ric-8A G(q) alpha subunit complex						mah	2009-11-16T04:48:05Z						cellular_component											owl:Class	
GO:0008737	biolink:NamedThing	L-fuculokinase activity	Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H(+).	got7fsn_ti	L-fuculokinase (phosphorylating)|ATP:L-fuculose 1-phosphotransferase activity|L-fuculose kinase activity											MetaCyc:FUCULOKIN-RXN|KEGG_REACTION:R03241|EC:2.7.1.51|RHEA:12376		molecular_function											owl:Class	
GO:0019200	biolink:NamedThing	carbohydrate kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.	got7fsn_ti												Reactome:R-HSA-8931653		molecular_function											owl:Class	
GO:0044533	biolink:NamedThing	positive regulation of apoptotic process in other organism	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism.	got7fsn_ti							jl	2012-03-21T11:25:24Z						biological_process											owl:Class	
GO:0044532	biolink:NamedThing	modulation of apoptotic process in other organism	A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism.	got7fsn_ti	regulation of apoptotic process in other organism						jl	2012-03-21T11:17:18Z						biological_process											owl:Class	
GO:0043829	biolink:NamedThing	tRNA-specific adenosine-37 deaminase activity	Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule.	got7fsn_ti	TAD1|tRNA-specific adenosine deaminase 1|tRNA(Ala)-A37 deaminase activity													molecular_function											owl:Class	
GO:0008251	biolink:NamedThing	tRNA-specific adenosine deaminase activity	Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule.	got7fsn_ti	tRNA-adenosine deaminase activity											Reactome:R-HSA-6782336|Reactome:R-HSA-6782311		molecular_function											owl:Class	
GO:0040025	biolink:NamedThing	vulval development	The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.	got7fsn_ti														biological_process											owl:Class	
GO:0048569	biolink:NamedThing	post-embryonic animal organ development	Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti	post-embryonic animal organogenesis													biological_process											owl:Class	
GO:0003041	biolink:NamedThing	excitation of vasomotor center by carotid body chemoreceptor signaling	The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.	got7fsn_ti	excitation of vasomotor center by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0002008	biolink:NamedThing	excitation of vasomotor center by chemoreceptor signaling	The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure.	got7fsn_ti	excitation of vasomotor center by chemoreceptor signalling													biological_process											owl:Class	
GO:0005185	biolink:NamedThing	neurohypophyseal hormone activity	The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin.	got7fsn_ti	neurohypophysial hormone activity													molecular_function											owl:Class	
GO:0005184	biolink:NamedThing	neuropeptide hormone activity	The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.	got7fsn_ti	neurohormone											Wikipedia:Neurohormone		molecular_function											owl:Class	
GO:0072681	biolink:NamedThing	fibronectin-dependent thymocyte migration	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix.	got7fsn_ti	fibronectin-dependent immature T cell migration|fibronectin-dependent immature T-lymphocyte migration|fibronectin-dependent immature T lymphocyte migration|fibronectin-dependent immature T-cell migration|fibronectin-dependent thymic lymphocyte migration						mah	2011-02-22T03:53:06Z						biological_process											owl:Class	
GO:0072680	biolink:NamedThing	extracellular matrix-dependent thymocyte migration	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin.	got7fsn_ti	extracellular matrix-dependent thymic lymphocyte migration|extracellular matrix-dependent immature T-cell migration|extracellular matrix-dependent immature T-lymphocyte migration|extracellular matrix-dependent immature T lymphocyte migration|extracellular matrix-dependent immature T cell migration						mah	2011-02-22T03:49:57Z						biological_process											owl:Class	
GO:0047312	biolink:NamedThing	L-phenylalanine:pyruvate aminotransferase activity	Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine.	got7fsn_ti	phenylalanine(histidine):pyruvate aminotransferase activity|L-phenylalanine:pyruvate transaminase activity|phenylalanine (histidine) aminotransferase activity|histidine aminotransferase activity|L-phenylalanine(L-histidine):pyruvate aminotransferase activity|phenylalanine(histidine) transaminase activity|L-histidine:pyruvate aminotransferase activity|phenylalanine(histidine) aminotransferase activity|histidine:pyruvate aminotransferase activity											Reactome:R-HSA-893593|RHEA:13053|KEGG_REACTION:R00692|EC:2.6.1.58|MetaCyc:2.6.1.58-RXN		molecular_function											owl:Class	
GO:0070546	biolink:NamedThing	L-phenylalanine aminotransferase activity	Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0051882	biolink:NamedThing	mitochondrial depolarization	The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.	got7fsn_ti	mitochondrion depolarization|mitochondria depolarization|mitochondrial membrane depolarization|mitochondrial depolarisation													biological_process											owl:Class	
GO:2000384	biolink:NamedThing	negative regulation of ectoderm development	Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development.	got7fsn_ti							vk	2011-02-15T03:17:27Z						biological_process											owl:Class	
GO:0030741	biolink:NamedThing	inositol 1-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	myo-inositol 3-O-methyltransferase activity|inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)|S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase activity|inositol D-1-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase activity|inositol 3-O-methyltransferase activity|S-adenosylmethionine:myo-inositol 3-methyltransferase activity											MetaCyc:MYO-INOSITOL-3-O-METHYLTRANSFERASE-RXN|RHEA:17565|KEGG_REACTION:R01188|EC:2.1.1.40		molecular_function											owl:Class	
GO:0045901	biolink:NamedThing	positive regulation of translational elongation	Any process that activates or increases the frequency, rate or extent of translational elongation.	got7fsn_ti	up-regulation of translational elongation|activation of translational elongation|up regulation of translational elongation|stimulation of translational elongation|upregulation of translational elongation													biological_process											owl:Class	
GO:0045727	biolink:NamedThing	positive regulation of translation	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.	got7fsn_ti	positive regulation of protein biosynthesis|positive regulation of protein anabolism|positive regulation of protein formation|positive regulation of protein synthesis|activation of protein biosynthetic process|positive regulation of protein biosynthetic process|upregulation of protein biosynthetic process|up-regulation of protein biosynthetic process|up regulation of protein biosynthetic process|stimulation of protein biosynthetic process										GO:0045946			biological_process											owl:Class	
GO:0044407	biolink:NamedThing	single-species biofilm formation in or on host organism	A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0044010	biolink:NamedThing	single-species biofilm formation	A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	got7fsn_ti	bfp-dependent aggregation|auto-aggregation|tfp-dependent aggregation|type IV pili-dependent aggregation|bundle-forming pili-dependent aggregation|bundle-forming fimbriae-dependent aggregation	https://github.com/geneontology/go-ontology/issues/18814									GO:0052000			biological_process											owl:Class	
GO:0085014	biolink:NamedThing	dormancy entry of symbiont in host	Entry into a dormant state of the symbiont within the host organism.	got7fsn_ti							jl	2010-05-19T02:33:26Z						biological_process											owl:Class	
GO:0022611	biolink:NamedThing	dormancy process	A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.	got7fsn_ti	multicellular organism dormancy process|spore dormancy process				In plants and animals, dormancy may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. In plants, dormancy may involve the formation of dormant buds, and may be preceded by the senescence of plant parts such as leaves in woody plants or most of the shoot system in herbaceous perennials. The exit from dormancy in vascular plants is marked by resumed growth of buds and/or growth of vascular cambium.									biological_process											owl:Class	
GO:0002274	biolink:NamedThing	myeloid leukocyte activation	A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.	got7fsn_ti	myeloid leucocyte activation													biological_process											owl:Class	
GO:0045321	biolink:NamedThing	leukocyte activation	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.	got7fsn_ti	leucocyte activation|immune cell activation											Wikipedia:Immunologic_activation		biological_process											owl:Class	
GO:0060044	biolink:NamedThing	negative regulation of cardiac muscle cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.	got7fsn_ti	negative regulation of heart muscle cell proliferation													biological_process											owl:Class	
GO:0097533	biolink:NamedThing	cellular stress response to acid chemical	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.	got7fsn_ti	cellular response to acid stress|cellular stress response to acid						pr	2013-11-12T13:07:12Z						biological_process											owl:Class	
GO:0097532	biolink:NamedThing	stress response to acid chemical	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.	got7fsn_ti	response to acid stress|stress response to acid						pr	2013-11-12T13:04:15Z						biological_process											owl:Class	
GO:0034599	biolink:NamedThing	cellular response to oxidative stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	got7fsn_ti	adaptive response to oxidative stress													biological_process											owl:Class	
GO:0004758	biolink:NamedThing	serine C-palmitoyltransferase activity	Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA.	got7fsn_ti	3-oxosphinganine synthetase activity|SPT|serine palmitoyltransferase|acyl-CoA:serine C-2 acyltransferase decarboxylating|palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity											KEGG_REACTION:R01281|EC:2.3.1.50|Reactome:R-HSA-428127|RHEA:14761|MetaCyc:SERINE-C-PALMITOYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0016454	biolink:NamedThing	C-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0035244	biolink:NamedThing	peptidyl-arginine C-methyltransferase activity	Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0008276	biolink:NamedThing	protein methyltransferase activity	Catalysis of the transfer of a methyl group (CH3-) to a protein.	got7fsn_ti												Reactome:R-HSA-9632182		molecular_function											owl:Class	
GO:0102620	biolink:NamedThing	3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity	Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15495		molecular_function											owl:Class	
GO:0102867	biolink:NamedThing	molybdenum cofactor sulfurtransferase activity	Catalysis of the reaction: 2 H+ + MoO2-molybdopterin cofactor(2-) + L-cysteine  <=> thio-molybdenum cofactor + L-alanine  + H2O.	got7fsn_ti												MetaCyc:RXN-8351|RHEA:42636|EC:2.8.1.9		molecular_function											owl:Class	
GO:0046692	biolink:NamedThing	sperm competition	Any process that contributes to the success of sperm fertilization in multiply-mated females.	got7fsn_ti												Wikipedia:Sperm_competition		biological_process											owl:Class	
GO:0048609	biolink:NamedThing	multicellular organismal reproductive process	The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.	got7fsn_ti	reproductive process in a multicellular organism|organismal reproductive process													biological_process											owl:Class	
GO:0120077	biolink:NamedThing	angiogenic sprout fusion	The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis.	got7fsn_ti	blood vessel anastomosis|angiogenic sprout fusion	https://github.com/geneontology/go-ontology/issues/13690					krc	2017-06-27T21:16:55Z						biological_process											owl:Class	
GO:0051650	biolink:NamedThing	establishment of vesicle localization	The directed movement of a vesicle to a specific location.	got7fsn_ti	establishment of vesicle localisation													biological_process											owl:Class	
GO:1990167	biolink:NamedThing	protein K27-linked deubiquitination	A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein.	got7fsn_ti							sp	2013-08-14T11:15:24Z						biological_process											owl:Class	
GO:0016579	biolink:NamedThing	protein deubiquitination	The removal of one or more ubiquitin groups from a protein.	got7fsn_ti	deubiquitination|protein deubiquitylation|protein deubiquitinylation										GO:0006514			biological_process											owl:Class	
GO:1990960	biolink:NamedThing	basophil homeostasis	The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti	basophilic leucocyte homeostasis						sl	2016-06-06T22:38:22Z						biological_process											owl:Class	
GO:0002262	biolink:NamedThing	myeloid cell homeostasis	The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0006614	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane	The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.	got7fsn_ti	ER translocation|SRP-dependent cotranslational protein-membrane targeting|SRP-dependent cotranslational membrane targeting													biological_process											owl:Class	
GO:0046352	biolink:NamedThing	disaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units.	got7fsn_ti	disaccharide breakdown|disaccharide catabolism|disaccharide degradation													biological_process											owl:Class	
GO:0015454	biolink:NamedThing	light-driven active transmembrane transporter activity	Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.	got7fsn_ti	light-driven pumps|Light absorption-driven transporters											TC:3.E		molecular_function											owl:Class	
GO:0015399	biolink:NamedThing	primary active transmembrane transporter activity	Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources.	got7fsn_ti	primary active transporter											TC:3		molecular_function											owl:Class	
GO:0032421	biolink:NamedThing	stereocilium bundle	A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes.	got7fsn_ti	stereocilia bundle													cellular_component											owl:Class	
GO:0098862	biolink:NamedThing	cluster of actin-based cell projections	A cell part consisting of multiple, closely packed actin-based cell projections.	got7fsn_ti														cellular_component											owl:Class	
GO:0090545	biolink:NamedThing	CHD-type complex	A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure.	got7fsn_ti							tb	2013-02-15T12:11:57Z						cellular_component											owl:Class	
GO:0070603	biolink:NamedThing	SWI/SNF superfamily-type complex	A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.	got7fsn_ti	SWI-SNF-type complex|SWI-SNF global transcription activator complex|BAF-type complex|SWI/SNF-type complex|SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex						mah	2009-04-29T12:55:46Z			GO:0090544			cellular_component											owl:Class	
GO:0019517	biolink:NamedThing	L-threonine catabolic process to D-lactate	The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate.	got7fsn_ti	L-threonine breakdown to D-lactate|L-threonine catabolic process to methylglyoxal|L-threonine degradation to D-lactate|L-threonine catabolic process to pyruvate|L-threonine catabolic process to (R)-lactate|L-threonine catabolism to D-lactate|threonine catabolic process to D-lactate											MetaCyc:THRDLCTCAT-PWY		biological_process											owl:Class	
GO:0006567	biolink:NamedThing	threonine catabolic process	The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.	got7fsn_ti	threonine catabolism|threonine degradation|threonine breakdown											MetaCyc:THREOCAT-PWY|UM-BBD_pathwayID:met		biological_process											owl:Class	
GO:0046994	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound.	got7fsn_ti												EC:1.12.5.-		molecular_function											owl:Class	
GO:0050313	biolink:NamedThing	sulfur dioxygenase activity	Catalysis of the reaction: sulfur + O2 + H2O = sulfite.	got7fsn_ti	sulphur dioxygenase activity|sulfur:oxygen oxidoreductase activity|S-sulfanylglutathione:oxygen oxidoreductase activity|sulfur oxygenase activity											RHEA:12981|Reactome:R-HSA-1614605|MetaCyc:FESGSHTHIO-RXN|EC:1.13.11.18		molecular_function											owl:Class	
GO:0043529	biolink:NamedThing	GET complex	An endoplasmic reticulum protein-containing complex that is conserved in eukaryotics and that mediates the insertion of tail-anchored proteins into the ER membrane. In yeast, includes Get1p, Get2p and Get3p proteins.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20244												cellular_component											owl:Class	
GO:0102509	biolink:NamedThing	cyanidin 3,5-diglucoside glucosidase activity	Catalysis of the reaction: cyanin betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-14436		molecular_function											owl:Class	
GO:0006949	biolink:NamedThing	syncytium formation	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0018133	biolink:NamedThing	peptide cross-linking via L-cysteine oxazolinecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue.	got7fsn_ti												RESID:AA0239		biological_process											owl:Class	
GO:0018157	biolink:NamedThing	peptide cross-linking via an oxazole or thiazole	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	got7fsn_ti	peptide heterocycle biosynthesis|peptide heterocycle synthesis|peptide heterocycle biosynthetic process|peptide heterocycle formation													biological_process											owl:Class	
GO:0009562	biolink:NamedThing	embryo sac nuclear migration	The directed movement of an embryo sac nucleus to the pole or center of the cell.	got7fsn_ti	female gametophyte nucleus migration|megagametophyte nucleus migration|embryo sac nucleus migration|megagametophyte nuclear migration|female gametophyte nuclear migration													biological_process											owl:Class	
GO:0007097	biolink:NamedThing	nuclear migration	The directed movement of the nucleus to a specific location within a cell.	got7fsn_ti	establishment of localization of nucleus|establishment of nucleus localization|nuclear positioning|establishment of cell nucleus localization|positioning of nucleus|establishment of nucleus localisation|establishment of position of nucleus|nuclear movement|nucleus positioning|nucleus migration										GO:0040023			biological_process											owl:Class	
GO:0052035	biolink:NamedThing	positive regulation by symbiont of host inflammatory response	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	stimulation by symbiont of host inflammatory response|up regulation by symbiont of host inflammatory response|up-regulation by symbiont of host inflammatory response|positive regulation by organism of inflammatory response of other organism involved in symbiotic interaction|upregulation by symbiont of host inflammatory response|activation by symbiont of host inflammatory response										GO:0052259			biological_process											owl:Class	
GO:0052032	biolink:NamedThing	modulation by symbiont of host inflammatory response	Any process in which a symbiont modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of inflammatory response of other organism involved in symbiotic interaction										GO:0052256			biological_process											owl:Class	
GO:0070021	biolink:NamedThing	transforming growth factor beta ligand-receptor complex	A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand.	got7fsn_ti	TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex|TGFbeta2 ligand-receptor complex|TGFb ligand-receptor complex|TGF-beta ligand-receptor complex|TGFbeta1-beta2 ligand-receptor complex|TGF-beta1-type II receptor-type I receptor complex|TGFbeta ligand-receptor complex|TGF-beta1-beta2 ligand-receptor complex|TGFbeta1 ligand-receptor complex|transforming growth factor beta1-type II receptor-type I receptor complex|TGF-beta2 ligand-receptor complex|TGF-beta 1:type II receptor:type I receptor complex|TGF-beta1 ligand-receptor complex													cellular_component											owl:Class	
GO:0044271	biolink:NamedThing	cellular nitrogen compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.	got7fsn_ti	nitrogen compound biosynthesis|nitrogen compound synthesis|nitrogen compound anabolism|nitrogen compound formation													biological_process											owl:Class	
GO:0034528	biolink:NamedThing	2-carboxy-2-hydroxy-8-carboxychromene isomerase activity	Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate.	got7fsn_ti												UM-BBD_reactionID:r0791|EC:5.3.99.-		molecular_function											owl:Class	
GO:0008925	biolink:NamedThing	maltose O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose.	got7fsn_ti	acetyl-CoA:maltose O-acetyltransferase activity|maltose transacetylase activity											EC:2.3.1.79|RHEA:10456|MetaCyc:MALTACETYLTRAN-RXN		molecular_function											owl:Class	
GO:0004314	biolink:NamedThing	[acyl-carrier-protein] S-malonyltransferase activity	Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein].	got7fsn_ti	malonyl-CoA:ACP transacylase activity|acyl-carrier-protein S-malonyltransferase activity|malonyl-CoA-acyl carrier protein transacylase activity|MCAT activity|malonyl transacylase activity|[acyl-carrier protein] S-malonyltransferase activity|malonyl transferase activity|malonyl-CoA:acyl carrier protein transacylase activity|FabD|acyl carrier proteinmalonyltransferase activity|malonyl-CoA:AcpM transacylase activity|malonyl-CoA:acyl-carrier-protein S-malonyltransferase activity|malonyl coenzyme A-acyl carrier protein transacylase activity|MAT|acyl carrier protein malonyltransferase activity|ACP S-malonyltransferase activity											MetaCyc:MALONYL-COA-ACP-TRANSACYL-RXN|Reactome:R-HSA-8933547|EC:2.3.1.39		molecular_function											owl:Class	
GO:0004312	biolink:NamedThing	fatty acid synthase activity	Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.	got7fsn_ti	acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)|fatty-acid synthase activity											RHEA:14993|EC:2.3.1.85|MetaCyc:FATTY-ACID-SYNTHASE-RXN|Reactome:R-HSA-75872		molecular_function											owl:Class	
GO:0050055	biolink:NamedThing	limonin-D-ring-lactonase activity	Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate.	got7fsn_ti	limonin lactone hydrolase activity|limonin-D-ring-lactone hydrolase activity|limonoate-D-ring-lactone lactonohydrolase activity											MetaCyc:LIMONIN-D-RING-LACTONASE-RXN|EC:3.1.1.36|RHEA:10896		molecular_function											owl:Class	
GO:0052083	biolink:NamedThing	suppression by symbiont of host cell-mediated immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	downregulation by symbiont of host cell-mediated immune response|down regulation by symbiont of host cell-mediated immune response|negative regulation by organism of host cell-based immune response|negative regulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction|inhibition by symbiont of host cell-mediated immune response|down-regulation by symbiont of host cell-mediated immune response										GO:0052278			biological_process											owl:Class	
GO:0030259	biolink:NamedThing	lipid glycosylation	Covalent attachment of a glycosyl residue to a lipid molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0043839	biolink:NamedThing	lipid A phosphate methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A.	got7fsn_ti	lipid A 1-phosphomethyltransferase activity|lipid A phosphomethyltransferase activity|LmtA|lipid A methyltransferase													molecular_function											owl:Class	
GO:0140383	biolink:NamedThing	4-hydroxytryptamine kinase activity	Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H(+).	got7fsn_ti							pg	2019-11-20T10:30:05Z				RHEA:55564|EC:2.7.1.222		molecular_function											owl:Class	
GO:0018594	biolink:NamedThing	tert-butanol 2-monooxygenase activity	Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol.	got7fsn_ti	tert-butyl alcohol 2-monooxygenase activity													molecular_function											owl:Class	
GO:0016671	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.	got7fsn_ti	oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor											EC:1.8.4.-		molecular_function											owl:Class	
GO:0031409	biolink:NamedThing	pigment binding	Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin.	got7fsn_ti														molecular_function											owl:Class	
GO:0030447	biolink:NamedThing	filamentous growth	The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.	got7fsn_ti														biological_process											owl:Class	
GO:0035853	biolink:NamedThing	chromosome passenger complex localization to spindle midzone	A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.	got7fsn_ti	chromosome passenger complex localisation to spindle midzone|chromosomal passenger complex localization to spindle midzone|CPC complex localization to spindle midzone|chromosome passenger complex localization to spindle equator|chromosome passenger complex localization to central spindle|CPC localization to spindle midzone						bf	2011-05-13T01:19:51Z						biological_process											owl:Class	
GO:0034629	biolink:NamedThing	cellular protein-containing complex localization	A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell.	got7fsn_ti	cellular protein complex localisation|establishment and maintenance of cellular protein complex localization|cellular protein complex localization													biological_process											owl:Class	
GO:0047211	biolink:NamedThing	alpha-1,4-glucan-protein synthase (ADP-forming) activity	Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP.	got7fsn_ti	ADPglucose:protein glucosyltransferase activity|ADP-glucose:protein 4-alpha-D-glucosyltransferase activity|adenosine diphosphoglucose-protein glucosyltransferase activity|1,4alpha-glucan-protein synthase (ADP-forming) activity|ADPglucose:protein 4-alpha-D-glucosyltransferase activity											MetaCyc:2.4.1.113-RXN|EC:2.4.1.113		molecular_function											owl:Class	
GO:0060136	biolink:NamedThing	embryonic process involved in female pregnancy	A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.	got7fsn_ti														biological_process											owl:Class	
GO:0102482	biolink:NamedThing	5-deoxy-D-glucuronate isomerase activity	Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate.	got7fsn_ti												EC:5.3.1.30|RHEA:25840|MetaCyc:RXN-14150		molecular_function											owl:Class	
GO:0051446	biolink:NamedThing	positive regulation of meiotic cell cycle	Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.	got7fsn_ti	upregulation of progression through meiotic cell cycle|positive regulation of meiotic cell cycle progression|up regulation of progression through meiotic cell cycle|stimulation of progression through meiotic cell cycle|up-regulation of progression through meiotic cell cycle|positive regulation of progression through meiotic cell cycle|activation of progression through meiotic cell cycle													biological_process											owl:Class	
GO:0051445	biolink:NamedThing	regulation of meiotic cell cycle	Any process that modulates the rate or extent of progression through the meiotic cell cycle.	got7fsn_ti	modulation of meiotic cell cycle progression|regulation of progression through meiotic cell cycle|meiotic cell cycle modulation|meiotic cell cycle regulator|meiotic cell cycle regulation|regulation of meiotic cell cycle progression													biological_process											owl:Class	
GO:0051328	biolink:NamedThing	meiotic interphase	The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.	got7fsn_ti	interphase of meiotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0051325	biolink:NamedThing	interphase	The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.	got7fsn_ti	karyostasis|resting phase				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Interphase		biological_process											owl:Class	
GO:0006022	biolink:NamedThing	aminoglycan metabolic process	The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.	got7fsn_ti	aminoglycan metabolism													biological_process											owl:Class	
GO:0043170	biolink:NamedThing	macromolecule metabolic process	The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti	multicellular organismal macromolecule metabolic process|macromolecule metabolism|biopolymer metabolic process|organismal macromolecule metabolism										GO:0043283|GO:0044259			biological_process											owl:Class	
GO:0090384	biolink:NamedThing	phagosome-lysosome docking	The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere.	got7fsn_ti	lysosome recruitment to phagosome						tb	2010-10-27T10:24:28Z						biological_process											owl:Class	
GO:0048278	biolink:NamedThing	vesicle docking	The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.	got7fsn_ti	vesicle to membrane docking													biological_process											owl:Class	
GO:0001983	biolink:NamedThing	baroreceptor response to increased systemic arterial blood pressure	The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels.	got7fsn_ti														biological_process											owl:Class	
GO:0001978	biolink:NamedThing	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control.	got7fsn_ti	baroreceptor feedback control of blood pressure|baroreceptor pressure buffer system|carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0031017	biolink:NamedThing	exocrine pancreas development	The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.	got7fsn_ti														biological_process											owl:Class	
GO:0042263	biolink:NamedThing	neuropeptide F receptor activity	Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.	got7fsn_ti	NPF receptor activity				Despite their naming, neuropeptide F (NPF) and short neuropeptide F (sNPF) are not closely related.									molecular_function											owl:Class	
GO:0008188	biolink:NamedThing	neuropeptide receptor activity	Combining with a neuropeptide to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0102654	biolink:NamedThing	1-18:1-2-16:0-phosphatidylglycerol trans-3 desaturase activity	Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:1-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-1725|RHEA:46764|EC:1.14.19.43		molecular_function											owl:Class	
GO:0033914	biolink:NamedThing	xylan 1,3-beta-xylosidase activity	Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans.	got7fsn_ti	1,3-beta-D-xylosidase, exo-1,3-beta-xylosidase activity|1,3-beta-D-xylan xylohydrolase activity|exo-1,3-beta-xylosidase activity|beta-1,3'-xylanase activity|exo-beta-1,3'-xylanase activity											MetaCyc:3.2.1.72-RXN|EC:3.2.1.72		molecular_function											owl:Class	
GO:0097599	biolink:NamedThing	xylanase activity	Catalysis of the hydrolysis of xylans, homopolysaccharides composed of xylose residues.	got7fsn_ti	xylosidase activity						pr	2014-05-06T13:46:48Z						molecular_function											owl:Class	
GO:0102362	biolink:NamedThing	esculetin 3-O-glucosyltransferase activity	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 3-O-beta-D-glucosyl-esculetin + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13472		molecular_function											owl:Class	
GO:0021970	biolink:NamedThing	corticospinal neuron axon guidance through the basilar pons	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues.	got7fsn_ti	corticospinal neuron axon pathfinding through the basilar pons													biological_process											owl:Class	
GO:0001863	biolink:NamedThing	collectin receptor activity	Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti					Note that collectins include such proteins as mannose-binding lectin (MBL) and surfactant proteins A and D (SP-A and SP-D).									molecular_function											owl:Class	
GO:0001847	biolink:NamedThing	opsonin receptor activity	Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0046739	biolink:NamedThing	transport of virus in multicellular host	The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs).	got7fsn_ti	spread of virus in multicellular host|spread of virus within multicellular host|viral spread within multicellular host													biological_process											owl:Class	
GO:0044000	biolink:NamedThing	movement in host	The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	movement of symbiont within host|movement of symbiont in host|symbiont movement in host|symbiont movement within host|movement within host													biological_process											owl:Class	
GO:0072014	biolink:NamedThing	proximal tubule development	The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.	got7fsn_ti							mah	2010-01-25T02:33:46Z						biological_process											owl:Class	
GO:0072080	biolink:NamedThing	nephron tubule development	The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.	got7fsn_ti							mah	2010-02-01T02:32:12Z						biological_process											owl:Class	
SO:0000673	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33697	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075119	biolink:NamedThing	induction by symbiont of host G protein-coupled receptor signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit|positive regulation by symbiont of host G-protein coupled receptor protein signal transduction|positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit|positive regulation by symbiont of host G protein-coupled receptor signal transduction|positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by symbiont of host G protein-coupled receptor signal transduction ; GO:0075088".						GO:0075128|GO:0075125|GO:0075122			biological_process											owl:Class	
GO:0021716	biolink:NamedThing	inferior olivary nucleus structural organization	The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	got7fsn_ti	inferior olivary nucleus structural organisation|inferior olive structural organization													biological_process											owl:Class	
GO:0000707	biolink:NamedThing	meiotic DNA recombinase assembly	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0061982	biolink:NamedThing	meiosis I cell cycle process	A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs.	got7fsn_ti	first meiotic cell division						dph	2018-02-14T22:27:20Z						biological_process											owl:Class	
GO:0042043	biolink:NamedThing	neurexin family protein binding	Binding to a neurexin, a synaptic cell surface protein related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.	got7fsn_ti	neuroligin										GO:0019963			molecular_function											owl:Class	
GO:0005102	biolink:NamedThing	signaling receptor binding	Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti	receptor binding|receptor ligand|receptor-associated protein activity				Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'.							Wikipedia:Ligand_(biochemistry)		molecular_function											owl:Class	
GO:0103081	biolink:NamedThing	methylthiopropylmalate dehydrogenase activity	Catalysis of the reaction: 3-(3'-methylthio)propylmalate <=> H+ + 2-oxo-6-methylthiohexanoate + carbon dioxide.	got7fsn_ti												MetaCyc:RXNQT-4165		molecular_function											owl:Class	
GO:0045296	biolink:NamedThing	cadherin binding	Binding to cadherin, a type I membrane protein involved in cell adhesion.	got7fsn_ti														molecular_function											owl:Class	
GO:0050839	biolink:NamedThing	cell adhesion molecule binding	Binding to a cell adhesion molecule.	got7fsn_ti	adhesive extracellular matrix constituent|cell adhesion molecule activity|cell adhesion receptor activity|CAM binding													molecular_function											owl:Class	
GO:0048878	biolink:NamedThing	chemical homeostasis	Any biological process involved in the maintenance of an internal steady state of a chemical.	got7fsn_ti														biological_process											owl:Class	
GO:0018366	biolink:NamedThing	chiral amino acid racemization	The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid.	got7fsn_ti														biological_process											owl:Class	
GO:0006520	biolink:NamedThing	cellular amino acid metabolic process	The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.	got7fsn_ti	cellular amino acid metabolism|amino acid and derivative metabolism|cellular amino acid and derivative metabolic process|amino acid metabolic process										GO:0006519			biological_process											owl:Class	
GO:0036441	biolink:NamedThing	2-dehydropantolactone reductase activity	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.	got7fsn_ti							bf	2013-09-30T16:26:27Z				RHEA:18981|KEGG_REACTION:R03155		molecular_function											owl:Class	
GO:0019664	biolink:NamedThing	mixed acid fermentation	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP.	got7fsn_ti	glucose catabolic process to mixed acids|glucose fermentation to mixed acids											Wikipedia:Mixed_acid_fermentation		biological_process											owl:Class	
GO:0019660	biolink:NamedThing	glycolytic fermentation	Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.	got7fsn_ti												MetaCyc:Pyruvate-Degredation		biological_process											owl:Class	
GO:0140502	biolink:NamedThing	effector-mediated suppression of host salicylic acid-mediated innate immune signalling	A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signalling.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19848					pg	2020-08-11T06:16:36Z						biological_process											owl:Class	
GO:0071546	biolink:NamedThing	pi-body	A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.	got7fsn_ti	intermitochondrial cement						mah	2010-01-12T05:44:12Z						cellular_component											owl:Class	
GO:0043186	biolink:NamedThing	P granule	A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes.	got7fsn_ti	germline granule|nuage|polar granule										GO:0018994			cellular_component											owl:Class	
GO:0005009	biolink:NamedThing	insulin-activated receptor activity	Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	insulin receptor activity				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand insulin. For receptors that bind other extracellular ligands, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.									molecular_function											owl:Class	
GO:0004714	biolink:NamedThing	transmembrane receptor protein tyrosine kinase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	got7fsn_ti	receptor protein tyrosine kinase activity|receptor protein-tyrosine kinase activity											Reactome:R-HSA-8987096|Reactome:R-HSA-8950423|Reactome:R-HSA-8986985|Reactome:R-HSA-8987070|EC:2.7.10.1|Reactome:R-HSA-8987042|Reactome:R-HSA-8950340|Reactome:R-HSA-8983300|Reactome:R-HSA-8987084|Reactome:R-HSA-8987012|Reactome:R-HSA-8950757|Reactome:R-HSA-8983309|Reactome:R-HSA-8950591|Reactome:R-HSA-8987040|Reactome:R-HSA-74742|Reactome:R-HSA-169905|Reactome:R-HSA-8983424|Reactome:R-HSA-8853792|Reactome:R-HSA-8987150|Reactome:R-HSA-8986995|Reactome:R-HSA-8987255|Reactome:R-HSA-8982163|Reactome:R-HSA-8950364|Reactome:R-HSA-8950537|Reactome:R-HSA-74715|Reactome:R-HSA-8987202|Reactome:R-HSA-74711|Reactome:R-HSA-8986994|Reactome:R-HSA-8983371|Reactome:R-HSA-167019|Reactome:R-HSA-8950405|Reactome:R-HSA-8987179|Reactome:R-HSA-8987141|Reactome:R-HSA-177933|Reactome:R-HSA-8987129|Reactome:R-HSA-198295|Reactome:R-HSA-8852552|Reactome:R-HSA-8950354|Reactome:R-HSA-8950269|Reactome:R-HSA-167683|Reactome:R-HSA-6784324|Reactome:R-HSA-166544|Reactome:R-HSA-8950485|Reactome:R-HSA-8950453|MetaCyc:2.7.10.1-RXN		molecular_function											owl:Class	
GO:0038170	biolink:NamedThing	somatostatin signaling pathway	The series of molecular signals generated as a consequence of the peptide somatostatin (SST) binding to a somatostatin receptor (SSTR). The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	somatostatin signalling pathway|SRIF signaling pathway|somatostatin-mediated signaling pathway|somatostatin-activated somatostatin receptor signaling pathway|SST signaling pathway|somatotrophin release inhibiting factor signaling pathway						bf	2012-06-12T10:33:21Z						biological_process											owl:Class	
GO:0098593	biolink:NamedThing	goblet cell theca	A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium.  It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles resembling the hoops of a barrel.	got7fsn_ti							dos	2014-03-11T14:52:33Z						cellular_component											owl:Class	
GO:0060036	biolink:NamedThing	notochord cell vacuolation	The assembly and arrangement of a vacuole within a cell of the notochord.	got7fsn_ti														biological_process											owl:Class	
GO:0007033	biolink:NamedThing	vacuole organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.	got7fsn_ti	vacuole biogenesis|vacuole organization and biogenesis|vacuole organisation|vacuolar assembly										GO:0044086			biological_process											owl:Class	
GO:0000460	biolink:NamedThing	maturation of 5.8S rRNA	Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0006364	biolink:NamedThing	rRNA processing	Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.	got7fsn_ti	35S primary transcript processing										GO:0006365			biological_process											owl:Class	
GO:0097329	biolink:NamedThing	response to antimetabolite	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.	got7fsn_ti							pr	2012-06-12T10:52:01Z						biological_process											owl:Class	
GO:0034552	biolink:NamedThing	respiratory chain complex II assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II.	got7fsn_ti														biological_process											owl:Class	
GO:0002421	biolink:NamedThing	B cell antigen processing and presentation following pinocytosis	B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.	got7fsn_ti	B-cell antigen processing and presentation following pinocytosis|B-lymphocyte antigen processing and presentation following pinocytosis|B lymphocyte antigen processing and presentation following pinocytosis													biological_process											owl:Class	
GO:0035855	biolink:NamedThing	megakaryocyte development	The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.	got7fsn_ti	megakaryocyte cell development						bf	2011-05-13T01:28:06Z						biological_process											owl:Class	
GO:0061515	biolink:NamedThing	myeloid cell development	The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.	got7fsn_ti							dph	2013-04-18T13:03:16Z						biological_process											owl:Class	
GO:0051778	biolink:NamedThing	ent-7-alpha-hydroxykaurenoate oxidase activity	Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).	got7fsn_ti					Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-kaurenoate oxidase activity ; GO:0051777' and 'gibberellin 12-aldehyde oxidase activity ; GO:0051779'.							MetaCyc:RXN1F-160|RHEA:22904		molecular_function											owl:Class	
GO:0030144	biolink:NamedThing	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors.	got7fsn_ti	UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase activity|alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase V activity|UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase activity|GnTV activity|alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-mannoside beta-1->6-acetylglucosaminyltransferase activity|alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine:alpha-mannoside-beta-1,6 N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase activity											EC:2.4.1.155|MetaCyc:2.4.1.155-RXN|Reactome:R-HSA-975916|Reactome:R-HSA-9696980|RHEA:16921		molecular_function											owl:Class	
GO:0060955	biolink:NamedThing	neural crest-derived cardiac glial cell fate commitment	The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.	got7fsn_ti							dph	2009-09-29T03:15:04Z						biological_process											owl:Class	
GO:0060953	biolink:NamedThing	cardiac glial cell fate commitment	The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.	got7fsn_ti							dph	2009-09-29T03:11:23Z						biological_process											owl:Class	
GO:0019487	biolink:NamedThing	anaerobic acetylene catabolic process	The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen.	got7fsn_ti	anaerobic acetylene catabolism|anaerobic acetylene degradation|anaerobic ethyne catabolic process|anaerobic ethyne catabolism|anaerobic acetylene breakdown											MetaCyc:P161-PWY		biological_process											owl:Class	
GO:0043454	biolink:NamedThing	alkyne catabolic process	The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.	got7fsn_ti	alkyne breakdown|alkyne catabolism|alkyne degradation													biological_process											owl:Class	
GO:0060535	biolink:NamedThing	trachea cartilage morphogenesis	The process in which the anatomical structures of cartilage in the trachea are generated and organized.	got7fsn_ti							dph	2009-04-10T09:07:48Z						biological_process											owl:Class	
GO:0060536	biolink:NamedThing	cartilage morphogenesis	The process in which the anatomical structures of cartilage are generated and organized.	got7fsn_ti							dph	2009-04-10T09:13:27Z						biological_process											owl:Class	
GO:0071197	biolink:NamedThing	Kv4.2-Kv4.3 channel complex	A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3.	got7fsn_ti							mah	2009-11-23T05:00:33Z				CORUM:609		cellular_component											owl:Class	
GO:0008076	biolink:NamedThing	voltage-gated potassium channel complex	A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.	got7fsn_ti	voltage-sensitive potassium channel complex|voltage gated potassium channel complex|voltage-dependent potassium channel complex											NIF_Subcellular:sao371494298		cellular_component											owl:Class	
GO:0010557	biolink:NamedThing	positive regulation of macromolecule biosynthetic process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti														biological_process											owl:Class	
GO:0010556	biolink:NamedThing	regulation of macromolecule biosynthetic process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti														biological_process											owl:Class	
GO:0062141	biolink:NamedThing	nuclear exosome targeting complex	A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts.	got7fsn_ti	NEXT complex						dph	2019-08-29T14:46:59Z						cellular_component											owl:Class	
GO:0097641	biolink:NamedThing	alpha-ketoglutarate-dependent xanthine dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate.	got7fsn_ti	alpha-ketoglutarate- and Fe(II)-dependent xanthine hydroxylase activity|alpha-ketoglutarate- and Fe(II)-dependent xanthine dioxygenase activity|2-oxoglutarate-dependent xanthine dioxygenase activity						pr	2014-09-03T14:55:42Z				RHEA:43120		molecular_function											owl:Class	
GO:0006513	biolink:NamedThing	protein monoubiquitination	Addition of a single ubiquitin group to a protein.	got7fsn_ti	protein monoubiquitylation|protein monoubiquitinylation													biological_process											owl:Class	
GO:0016567	biolink:NamedThing	protein ubiquitination	The process in which one or more ubiquitin groups are added to a protein.	got7fsn_ti	protein ubiquitinylation|protein ubiquitylation													biological_process											owl:Class	
GO:0106310	biolink:NamedThing	protein serine kinase activity	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20114			Note that this term is to annotate proteins the specifically phosphorylate a serine residue on a protein. An example is human PIKFYVE (UniProt:Q9Y2I7). For dual specificity protein kinases, use 'protein serine/threonine kinase activity' ; GO:0004712.		hjd	2020-09-22T20:01:17Z				RHEA:17989		molecular_function											owl:Class	
GO:0034772	biolink:NamedThing	histone H4-K20 dimethylation	The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone.	got7fsn_ti	histone lysine H4 K20 dimethylation|histone H4 K20 dimethylation													biological_process											owl:Class	
GO:0018027	biolink:NamedThing	peptidyl-lysine dimethylation	The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.	got7fsn_ti												RESID:AA0075		biological_process											owl:Class	
GO:0070415	biolink:NamedThing	trehalose metabolism in response to cold stress	The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.	got7fsn_ti	trehalose metabolic process involved in response to cold stress													biological_process											owl:Class	
GO:0070413	biolink:NamedThing	trehalose metabolism in response to stress	The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.	got7fsn_ti	trehalose metabolic process involved in response to stress													biological_process											owl:Class	
GO:0036094	biolink:NamedThing	small molecule binding	Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.	got7fsn_ti					Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.		bf	2012-01-17T04:20:34Z						molecular_function											owl:Class	
GO:0034656	biolink:NamedThing	nucleobase-containing small molecule catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.	got7fsn_ti	nucleobase, nucleoside and nucleotide catabolism|nucleobase, nucleoside and nucleotide degradation|nucleobase, nucleoside and nucleotide breakdown													biological_process											owl:Class	
GO:0102521	biolink:NamedThing	tRNA-4-demethylwyosine synthase activity	Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine  + N1-methylguanine37 in tRNAPhe = L-methionine  + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe.	got7fsn_ti												EC:4.1.3.44|MetaCyc:RXN-14516|RHEA:36347		molecular_function											owl:Class	
GO:0002346	biolink:NamedThing	B cell positive selection	Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor.	got7fsn_ti	B lymphocyte positive selection|B-lymphocyte positive selection|B-cell positive selection													biological_process											owl:Class	
GO:0002339	biolink:NamedThing	B cell selection	The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.	got7fsn_ti	B-cell selection|B lymphocyte selection|B-lymphocyte selection													biological_process											owl:Class	
GO:0035220	biolink:NamedThing	wing disc development	Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.	got7fsn_ti														biological_process											owl:Class	
GO:0007444	biolink:NamedThing	imaginal disc development	The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).	got7fsn_ti														biological_process											owl:Class	
GO:0047495	biolink:NamedThing	membrane-oligosaccharide glycerophosphotransferase activity	Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another.	got7fsn_ti	periplasmic phosphoglycerotransferase activity|membrane-derived-oligosaccharide-6-(glycerophospho)-D-glucose:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity|phosphoglycerol cyclase activity											MetaCyc:2.7.8.21-RXN|EC:2.7.8.21		molecular_function											owl:Class	
GO:0016035	biolink:NamedThing	zeta DNA polymerase complex	A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.	got7fsn_ti														cellular_component											owl:Class	
GO:0046912	biolink:NamedThing	acyltransferase, acyl groups converted into alkyl on transfer	Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.	got7fsn_ti	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	https://github.com/geneontology/go-ontology/issues/20486										EC:2.3.3.-		molecular_function											owl:Class	
GO:0000266	biolink:NamedThing	mitochondrial fission	The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.	got7fsn_ti	mitochondrial proliferation|mitochondrial division													biological_process											owl:Class	
GO:0007005	biolink:NamedThing	mitochondrion organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.	got7fsn_ti	mitochondrion organization and biogenesis|mitochondria organization|mitochondrion organisation													biological_process											owl:Class	
GO:0006874	biolink:NamedThing	cellular calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.	got7fsn_ti	regulation of calcium ion concentration													biological_process											owl:Class	
GO:0006875	biolink:NamedThing	cellular metal ion homeostasis	Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.	got7fsn_ti	cellular heavy metal ion homeostasis													biological_process											owl:Class	
GO:0016125	biolink:NamedThing	sterol metabolic process	The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti	sterol metabolism													biological_process											owl:Class	
GO:0043726	biolink:NamedThing	5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity	Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate.	got7fsn_ti	pyrimidine phosphatase activity										GO:0019173	MetaCyc:RIBOPHOSPHAT-RXN|RHEA:25197		molecular_function											owl:Class	
GO:0006036	biolink:NamedThing	cuticle chitin catabolic process	The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.	got7fsn_ti	cuticle chitin breakdown|cuticle chitin catabolism|cuticle chitin degradation													biological_process											owl:Class	
GO:0006032	biolink:NamedThing	chitin catabolic process	The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.	got7fsn_ti	beta-1,4-linked N-acetylglucosamine catabolic process|chitin breakdown|chitin degradation|chitin catabolism|beta-1,4-linked N-acetylglucosamine catabolism													biological_process											owl:Class	
GO:0045204	biolink:NamedThing	MAPK export from nucleus	The directed movement of a MAP kinase from the nucleus to the cytoplasm.	got7fsn_ti	MAPK-nucleus export|MAPK export out of nucleus|MAPK export from cell nucleus|MAPK transport from nucleus to cytoplasm|cytoplasmic translocation of mitogen-activated protein kinase|cytoplasmic translocation of MAP kinase													biological_process											owl:Class	
GO:0006611	biolink:NamedThing	protein export from nucleus	The directed movement of a protein from the nucleus into the cytoplasm.	got7fsn_ti	protein export out of nucleus|protein transport from nucleus to cytoplasm|protein export from cell nucleus|protein-nucleus export|copper-induced protein export from nucleus										GO:0097349			biological_process											owl:Class	
GO:0050959	biolink:NamedThing	echolocation	Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning.	got7fsn_ti	perception of environment using reflected sound waves|biological sonar											Wikipedia:Echolocation		biological_process											owl:Class	
GO:0050877	biolink:NamedThing	nervous system process	A organ system process carried out by any of the organs or tissues of neurological system.	got7fsn_ti	neurophysiological process|pan-neural process|neurological system process	https://github.com/geneontology/go-ontology/issues/13824												biological_process											owl:Class	
GO:1904058	biolink:NamedThing	positive regulation of sensory perception of pain	Any process that activates or increases the frequency, rate or extent of sensory perception of pain.	got7fsn_ti	upregulation of sensory perception of pain|positive regulation of perception of physiological pain|activation of nociception|activation of sensory perception of pain|up-regulation of perception of physiological pain|up-regulation of sensory perception of pain|up regulation of sensory perception of pain|up regulation of nociception|upregulation of perception of physiological pain|positive regulation of nociception|upregulation of nociception|up regulation of perception of physiological pain|activation of perception of physiological pain|up-regulation of nociception						sl	2015-03-18T20:34:03Z						biological_process											owl:Class	
GO:0051930	biolink:NamedThing	regulation of sensory perception of pain	Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.	got7fsn_ti														biological_process											owl:Class	
GO:0036509	biolink:NamedThing	trimming of terminal mannose on B branch	The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.	got7fsn_ti	conversion of (Man)9(GlcNAc)2 to (Man)8B(GlcNAc)2|conversion of M9 to M8B|glycoprotein mannose trimming on B branch				Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T14:02:44Z				KEGG_REACTION:R06722		biological_process											owl:Class	
GO:1904380	biolink:NamedThing	endoplasmic reticulum mannose trimming	Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC).	got7fsn_ti	protein alpha-1,2-demannosylation in ER|protein alpha-1,2-demannosylation in endoplasmic reticulum|glycoprotein mannose trimming in endoplasmic reticulum quality control compartment|protein alpha-1,2-demannosylation in endoplasmic reticulum quality control compartment|ER protein alpha-1,2-demannosylation|protein alpha-1,2-demannosylation in ER-derived quality control compartment|glycoprotein mannose trimming in ERQC|protein alpha-1,2-demannosylation in ER quality control compartment|glycoprotein mannose trimming in ER-derived quality control compartment|ER mannose trimming|glycoprotein mannose trimming in ER quality control compartment|protein alpha-1,2-demannosylation in ERQC						bf	2015-06-23T09:35:41Z						biological_process											owl:Class	
GO:1900046	biolink:NamedThing	regulation of hemostasis	Any process that modulates the frequency, rate or extent of hemostasis.	got7fsn_ti							jl	2012-01-19T03:23:38Z						biological_process											owl:Class	
GO:0002519	biolink:NamedThing	natural killer cell tolerance induction	Tolerance induction of natural killer cells.	got7fsn_ti	NK cell tolerance induction													biological_process											owl:Class	
GO:0002507	biolink:NamedThing	tolerance induction	A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.	got7fsn_ti														biological_process											owl:Class	
GO:0072417	biolink:NamedThing	response to spindle checkpoint signaling	A process that occurs in response to signals generated as a result of spindle checkpoint signaling.	got7fsn_ti	response to signal involved in spindle checkpoint|spindle checkpoint effector process						mah	2010-12-08T03:56:04Z						biological_process											owl:Class	
GO:0072396	biolink:NamedThing	response to cell cycle checkpoint signaling	A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.	got7fsn_ti	response to signal involved in G1/S transition checkpoint|response to G2/M transition checkpoint signaling|cell cycle checkpoint effector process|G2/M transition checkpoint effector process|response to signal involved in cell cycle checkpoint|response to G1/S transition checkpoint signaling|G1/S transition checkpoint effector process|response to signal involved in G2/M transition checkpoint						mah	2010-12-08T03:05:46Z			GO:0072405|GO:0072408			biological_process											owl:Class	
GO:0005451	biolink:NamedThing	monovalent cation:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out).	got7fsn_ti	monovalent cation:hydrogen antiporter activity											Reactome:R-HSA-2889070		molecular_function											owl:Class	
GO:0005141	biolink:NamedThing	interleukin-10 receptor binding	Binding to an interleukin-10 receptor.	got7fsn_ti	interleukin-10 receptor ligand|IL-10													molecular_function											owl:Class	
GO:0019982	biolink:NamedThing	interleukin-7 binding	Binding to interleukin-7.	got7fsn_ti	IL-7 binding													molecular_function											owl:Class	
GO:0090493	biolink:NamedThing	catecholamine uptake	The directed movement of catecholamine into a cell.	got7fsn_ti							tb	2012-10-17T11:06:17Z						biological_process											owl:Class	
GO:0051937	biolink:NamedThing	catecholamine transport	The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	got7fsn_ti														biological_process											owl:Class	
GO:0071227	biolink:NamedThing	cellular response to molecule of oomycetes origin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.	got7fsn_ti	cellular response to oomycetes associated molecule						mah	2009-12-03T01:55:09Z						biological_process											owl:Class	
GO:1990200	biolink:NamedThing	SsuD-SsuE complex	A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation.	got7fsn_ti	two-component alkanesulfonate monooxygenase system						bhm	2013-10-03T12:59:26Z						cellular_component											owl:Class	
GO:0039684	biolink:NamedThing	rolling circle single-stranded viral DNA replication	A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome.	got7fsn_ti	ssDNA rolling circle replication						bf	2013-10-17T14:15:48Z				VZ:1941		biological_process											owl:Class	
GO:0039682	biolink:NamedThing	rolling circle viral DNA replication	A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA.	got7fsn_ti							bf	2013-10-17T14:13:51Z						biological_process											owl:Class	
GO:0008682	biolink:NamedThing	2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity	Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone.	got7fsn_ti	demethoxyubiquinone monooxygenase|demethoxy-ubiquinone hydroxylase											RHEA:50908|EC:1.14.99.60|MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN		molecular_function											owl:Class	
GO:0004497	biolink:NamedThing	monooxygenase activity	Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.	got7fsn_ti	hydroxylase activity											Reactome:R-HSA-211910|Reactome:R-HSA-211962|Reactome:R-HSA-5662692|Reactome:R-HSA-6786239|Reactome:R-HSA-76456|Reactome:R-HSA-76354|Reactome:R-HSA-2161814|Reactome:R-HSA-211988|Reactome:R-HSA-213175|Reactome:R-HSA-9018874|Reactome:R-HSA-9027042|Reactome:R-HSA-143468|Reactome:R-HSA-215526|Reactome:R-HSA-156526|Reactome:R-HSA-76373|Reactome:R-HSA-211959|Reactome:R-HSA-76426|Reactome:R-HSA-5423678|Reactome:R-HSA-211948|Reactome:R-HSA-5423672|Reactome:R-HSA-211924|Reactome:R-HSA-2161795|Reactome:R-HSA-5605147|Reactome:R-HSA-217258|Reactome:R-HSA-9037761|Reactome:R-HSA-2161899|Reactome:R-HSA-9027321|Reactome:R-HSA-5662662|Reactome:R-HSA-76386|Reactome:R-HSA-76466|Reactome:R-HSA-76416|Reactome:R-HSA-212004|Reactome:R-HSA-211960|Reactome:R-HSA-2161940|Reactome:R-HSA-211919|Reactome:R-HSA-5423664|Reactome:R-HSA-76472|Reactome:R-HSA-76475|Reactome:R-HSA-76434|Reactome:R-HSA-211968|Reactome:R-HSA-212005|Reactome:R-HSA-211991|Reactome:R-HSA-5602272|Reactome:R-HSA-2162191|Reactome:R-HSA-211882|Reactome:R-HSA-9027043|Reactome:R-HSA-211951|Reactome:R-HSA-76397|Reactome:R-HSA-5423647|Reactome:R-HSA-9027044|Reactome:R-HSA-9027302|Reactome:R-HSA-5602242|Reactome:R-HSA-5602295|Reactome:R-HSA-211904|Reactome:R-HSA-2161890|Reactome:R-HSA-5663050|Reactome:R-HSA-8865107|Reactome:R-HSA-211929		molecular_function											owl:Class	
GO:0031205	biolink:NamedThing	endoplasmic reticulum Sec complex	An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0031946	biolink:NamedThing	regulation of glucocorticoid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.	got7fsn_ti														biological_process											owl:Class	
GO:0090030	biolink:NamedThing	regulation of steroid hormone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.	got7fsn_ti							tb	2009-08-03T10:38:27Z						biological_process											owl:Class	
GO:0045821	biolink:NamedThing	positive regulation of glycolytic process	Any process that activates or increases the frequency, rate or extent of glycolysis.	got7fsn_ti	upregulation of glycolysis|stimulation of glycolysis|activation of glycolysis|up-regulation of glycolysis|up regulation of glycolysis													biological_process											owl:Class	
GO:0031331	biolink:NamedThing	positive regulation of cellular catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.	got7fsn_ti	stimulation of cellular catabolic process|up-regulation of cellular catabolic process|positive regulation of cellular degradation|positive regulation of cellular breakdown|activation of cellular catabolic process|upregulation of cellular catabolic process|up regulation of cellular catabolic process|positive regulation of cellular catabolism													biological_process											owl:Class	
GO:0003976	biolink:NamedThing	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.	got7fsn_ti	UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase activity|N-acetylglucosaminylphosphotransferase activity|lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase activity|UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase activity|N-acetylglucosaminyl phosphotransferase activity|UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-1-phosphotransferase activity|UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase activity|UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase activity											MetaCyc:2.7.8.17-RXN|EC:2.7.8.17|RHEA:13581		molecular_function											owl:Class	
GO:0032302	biolink:NamedThing	MutSbeta complex	A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.	got7fsn_ti	MMR complex|MSH2/MSH3 complex													cellular_component											owl:Class	
GO:0031157	biolink:NamedThing	regulation of aggregate size involved in sorocarp development	Any process that modulates the size of the aggregate formed during sorocarp formation.	got7fsn_ti	regulation of aggregation during fruiting body formation|regulation of aggregation during fruiting body biosynthesis													biological_process											owl:Class	
GO:0047025	biolink:NamedThing	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity	Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein].	got7fsn_ti	3-oxoacyl-acyl-carrier-protein reductase (NADH)|3-oxoacyl-ACP reductase (NADH) activity|3-oxoacyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide) reductase activity|3-oxoacyl-[acyl-carrier protein] reductase (NADH) activity|(3R)-3-hydroxyacyl-acyl-carrier-protein:NAD+ oxidoreductase activity											EC:1.1.1.212|MetaCyc:1.1.1.212-RXN|RHEA:19913		molecular_function											owl:Class	
GO:0090060	biolink:NamedThing	regulation of metaxylem development	Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.	got7fsn_ti							tb	2009-08-11T03:14:54Z						biological_process											owl:Class	
GO:2000026	biolink:NamedThing	regulation of multicellular organismal development	Any process that modulates the frequency, rate or extent of multicellular organismal development.	got7fsn_ti							tb	2010-08-05T11:25:59Z						biological_process											owl:Class	
GO:0052103	biolink:NamedThing	induction by symbiont of host induced systemic resistance	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of induced systemic resistance in other organism involved in symbiotic interaction|induction by symbiont of induced systemic resistance in host|up-regulation by symbiont of induced systemic resistance in host|positive regulation by organism of induced systemic resistance in other organism involved in symbiotic interaction|up regulation by symbiont of induced systemic resistance in host|positive regulation by symbiont of host induced systemic resistance|activation by symbiont of induced systemic resistance in host|upregulation by symbiont of induced systemic resistance in host|stimulation by symbiont of induced systemic resistance in host|positive regulation by symbiont of induced systemic resistance in host|activation by organism of ISR in host|activation by organism of induced systemic resistance in host|induction by organism of ISR in host										GO:0052532|GO:0052533|GO:0052288			biological_process											owl:Class	
GO:0052159	biolink:NamedThing	modulation by symbiont of host induced systemic resistance	Any process in which a symbiont modulates the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of induced systemic resistance in host|modulation by organism of induced systemic resistance in other organism involved in symbiotic interaction										GO:0052298			biological_process											owl:Class	
GO:0001571	biolink:NamedThing	non-tyrosine kinase fibroblast growth factor receptor activity	Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity.	got7fsn_ti	non-tyrosine kinase FGF receptor activity|non-tyrosine kinase FGFR activity													molecular_function											owl:Class	
GO:1904362	biolink:NamedThing	regulation of calcitonin secretion	Any process that modulates the frequency, rate or extent of calcitonin secretion.	got7fsn_ti							sl	2015-06-15T17:54:52Z						biological_process											owl:Class	
GO:0090276	biolink:NamedThing	regulation of peptide hormone secretion	Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.	got7fsn_ti							tb	2010-02-05T02:56:39Z						biological_process											owl:Class	
GO:0044403	biolink:NamedThing	biological process involved in symbiotic interaction	A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.	got7fsn_ti	commensalism|symbiotic interaction between organisms|parasitism|symbiotic interaction|symbiosis|symbiotic interaction between species|symbiotic interaction between host and organism|host-pathogen interaction|symbiotic process|symbiosis, encompassing mutualism through parasitism	https://github.com/geneontology/go-ontology/issues/14807|https://github.com/geneontology/go-ontology/issues/20191									GO:0072519|GO:0085031|GO:0043298|GO:0044404			biological_process											owl:Class	
GO:0044419	biolink:NamedThing	biological process involved in interspecies interaction between organisms	Any process evolved to enable an interaction with an organism of a different species.	got7fsn_ti	interspecies interaction|interaction with another species|interspecies interaction between organisms|interspecies interaction with other organisms	https://github.com/geneontology/go-ontology/issues/20191												biological_process											owl:Class	
GO:0045049	biolink:NamedThing	protein insertion into ER membrane by N-terminal cleaved signal sequence	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER.	got7fsn_ti	protein insertion into endoplasmic reticulum membrane by N-terminal cleaved signal sequence|N-terminal cleaved signal sequence mediated protein insertion into ER membrane|protein insertion into ER membrane, N-terminal cleaved signal sequence mediated|protein-endoplasmic reticulum insertion by N-terminal cleaved signal sequence|protein-ER insertion by N-terminal cleaved signal sequence													biological_process											owl:Class	
GO:0045048	biolink:NamedThing	protein insertion into ER membrane	The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane.	got7fsn_ti	positioning of protein in ER membrane|integral ER membrane protein localization|integral ER membrane protein positioning|protein insertion into endoplasmic reticulum membrane|localization of protein in ER membrane|protein-ER insertion|protein-endoplasmic reticulum insertion													biological_process											owl:Class	
GO:0034918	biolink:NamedThing	3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0930		molecular_function											owl:Class	
GO:0097341	biolink:NamedThing	zymogen inhibition	Any process that prevents the proteolytic processing of an inactive enzyme to an active form.	got7fsn_ti	prevention of zymogen activation						pr	2012-06-18T11:25:45Z						biological_process											owl:Class	
GO:0010955	biolink:NamedThing	negative regulation of protein processing	Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.	got7fsn_ti	negative regulation of protein maturation by peptide bond cleavage						tb	2009-04-27T12:10:19Z						biological_process											owl:Class	
GO:0045105	biolink:NamedThing	intermediate filament polymerization or depolymerization	Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament.	got7fsn_ti														biological_process											owl:Class	
GO:0043933	biolink:NamedThing	protein-containing complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.	got7fsn_ti	protein complex subunit organization|macromolecular complex organization|cellular macromolecular complex subunit organisation|macromolecular complex subunit organisation|protein complex subunit organisation|cellular macromolecular complex organization|cellular macromolecular complex subunit organization|macromolecular complex subunit organization						mah	2010-09-08T10:01:42Z			GO:0034600|GO:0071822|GO:0034621			biological_process											owl:Class	
GO:0071747	biolink:NamedThing	IgA B cell receptor complex	An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	got7fsn_ti	membrane-bound IgA1|surface IgA1|surface IgA|membrane-bound IgA2|membrane-bound IgA|surface IgA2				Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0071745	biolink:NamedThing	IgA immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	IgA1 antibody|IgA2 antibody				Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0048790	biolink:NamedThing	maintenance of presynaptic active zone structure	A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters.	got7fsn_ti	maintenance of pre-synaptic active zone structure													biological_process											owl:Class	
GO:1990709	biolink:NamedThing	presynaptic active zone organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone.	got7fsn_ti	presynaptic active zone organisation						pr	2015-03-20T10:16:24Z						biological_process											owl:Class	
GO:0097100	biolink:NamedThing	supercoiled DNA binding	Binding to supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.	got7fsn_ti							pr	2011-07-12T03:28:57Z						molecular_function											owl:Class	
GO:0003690	biolink:NamedThing	double-stranded DNA binding	Binding to double-stranded DNA.	got7fsn_ti	dsDNA binding													molecular_function											owl:Class	
GO:0008174	biolink:NamedThing	mRNA methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0018132	biolink:NamedThing	peptide cross-linking via L-cysteine oxazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	got7fsn_ti												RESID:AA0238		biological_process											owl:Class	
GO:0010796	biolink:NamedThing	regulation of multivesicular body size	Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:0051036	biolink:NamedThing	regulation of endosome size	Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis.	got7fsn_ti	endosome enlargement													biological_process											owl:Class	
GO:0043171	biolink:NamedThing	peptide catabolic process	The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.	got7fsn_ti	peptide breakdown|peptide degradation|peptide catabolism													biological_process											owl:Class	
GO:0044248	biolink:NamedThing	cellular catabolic process	The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.	got7fsn_ti	cellular breakdown|cellular catabolism|cellular degradation													biological_process											owl:Class	
GO:0033564	biolink:NamedThing	anterior/posterior axon guidance	The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	got7fsn_ti	anterior-posterior axon guidance|anterior/posterior axon pathfinding													biological_process											owl:Class	
GO:0044065	biolink:NamedThing	regulation of respiratory system process	Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.	got7fsn_ti														biological_process											owl:Class	
GO:0043576	biolink:NamedThing	regulation of respiratory gaseous exchange	Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.	got7fsn_ti														biological_process											owl:Class	
GO:0071372	biolink:NamedThing	cellular response to follicle-stimulating hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.	got7fsn_ti	cellular response to follicle stimulating hormone stimulus|cellular response to FSH stimulus						mah	2009-12-11T03:15:56Z						biological_process											owl:Class	
GO:0032354	biolink:NamedThing	response to follicle-stimulating hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.	got7fsn_ti	response to follicle-stimulating hormone stimulus|response to FSH stimulus|response to follicle stimulating hormone stimulus													biological_process											owl:Class	
GO:0071217	biolink:NamedThing	cellular response to external biotic stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.	got7fsn_ti							mah	2009-12-03T01:14:27Z						biological_process											owl:Class	
GO:0071216	biolink:NamedThing	cellular response to biotic stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.	got7fsn_ti	cellular response to biotic stress				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-03T01:09:08Z						biological_process											owl:Class	
GO:0002014	biolink:NamedThing	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure	The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0042310	biolink:NamedThing	vasoconstriction	A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure.	got7fsn_ti	negative regulation of blood vessel size										GO:0045908	Wikipedia:Vasoconstriction		biological_process											owl:Class	
GO:0009432	biolink:NamedThing	SOS response	An error-prone process for repairing damaged microbial DNA.	got7fsn_ti												Wikipedia:SOS_response		biological_process											owl:Class	
GO:0006974	biolink:NamedThing	cellular response to DNA damage stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.	got7fsn_ti	response to genotoxic stress|cellular DNA damage response|DNA damage response|response to DNA damage stimulus										GO:0034984			biological_process											owl:Class	
GO:0032574	biolink:NamedThing	5'-3' RNA helicase activity	Unwinding of an RNA helix in the 5' to 3' direction, driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent 5'-3' RNA helicase activity|ATP-dependent 5' to 3' RNA helicase activity|5' to 3' RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612									GO:0032575	Reactome:R-HSA-9694265|Reactome:R-HSA-9682695		molecular_function											owl:Class	
GO:0003724	biolink:NamedThing	RNA helicase activity	Unwinding of an RNA helix, driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612									GO:0004004	EC:3.6.4.13|Reactome:R-HSA-72647|MetaCyc:ADENOSINETRIPHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0043011	biolink:NamedThing	myeloid dendritic cell differentiation	The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.	got7fsn_ti												Wikipedia:Dendritic_cell		biological_process											owl:Class	
GO:0001773	biolink:NamedThing	myeloid dendritic cell activation	The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti														biological_process											owl:Class	
GO:1990626	biolink:NamedThing	mitochondrial outer membrane fusion	The membrane organization process that joins two mitochondrial outer membranes to form a single membrane.	got7fsn_ti	mitochondrion outer membrane fusion						vw	2015-02-02T11:32:17Z						biological_process											owl:Class	
GO:0007366	biolink:NamedThing	periodic partitioning by pair rule gene	Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.	got7fsn_ti														biological_process											owl:Class	
GO:0007365	biolink:NamedThing	periodic partitioning	The regionalization process that divides the spatial regions of an embryo into serially repeated regions.	got7fsn_ti					Note that examples of periodic partitions are tagmata, segments or parasegments.									biological_process											owl:Class	
GO:0031414	biolink:NamedThing	N-terminal protein acetyltransferase complex	A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule.	got7fsn_ti	NAT complex													cellular_component											owl:Class	
GO:0031248	biolink:NamedThing	protein acetyltransferase complex	A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule.	got7fsn_ti														cellular_component											owl:Class	
GO:0043752	biolink:NamedThing	adenosylcobinamide kinase activity	Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP).	got7fsn_ti	AdoCbi kinase/AdoCbi-phosphate guanylyltransferase|CobU|RTP:adenosylcobinamide phosphotransferase activity|adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase											MetaCyc:2.7.1.156-RXN|EC:2.7.1.156		molecular_function											owl:Class	
GO:0000986	biolink:NamedThing	bacterial-type cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream cis-regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the promoter of a bacterial gene (or cistron, or operon).	got7fsn_ti	eubacterial-type RNA polymerase regulatory transcription factor sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding|bacterial-type proximal promoter sequence-specific DNA binding|bacterial-type RNA polymerase upstream activating sequence (UAS) sequence-specific DNA binding|bacterial-type RNA polymerase enhancer sequence-specific DNA binding						krc	2011-01-27T03:42:53Z			GO:0001150			molecular_function											owl:Class	
GO:0000984	biolink:NamedThing	bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding	Binding to a sequence of DNA that is part of a regulatory region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase.	got7fsn_ti	eubacterial-type RNA polymerase regulatory region DNA binding|eubacterial-type RNA polymerase regulatory region sequence-specific DNA binding|bacterial-type RNA polymerase regulatory region DNA binding				To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2010-08-10T02:58:18Z			GO:0001017			molecular_function											owl:Class	
GO:0039656	biolink:NamedThing	modulation by virus of host gene expression	The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.	got7fsn_ti	regulation by virus of host gene expression						bf	2013-06-20T15:28:26Z						biological_process											owl:Class	
GO:0090409	biolink:NamedThing	malonyl-CoA synthetase activity	Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate.	got7fsn_ti							tb	2011-06-10T01:51:16Z				MetaCyc:RXN-12359|RHEA:32139|EC:6.2.1.n3		molecular_function											owl:Class	
GO:1990059	biolink:NamedThing	fruit valve development	The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces.	got7fsn_ti							dhl	2013-03-12T21:21:15Z						biological_process											owl:Class	
GO:0035454	biolink:NamedThing	extrinsic component of stromal side of plastid inner membrane	The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.	got7fsn_ti	peripheral to stromal side of plastid inner membrane|extrinsic to stromal leaflet of plastid inner membrane|extrinsic to stromal side of plastid inner membrane						bf	2010-04-16T10:23:12Z						cellular_component											owl:Class	
GO:0035453	biolink:NamedThing	extrinsic component of plastid inner membrane	The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to plastid inner membrane|peripheral to plastid inner membrane						bf	2010-04-16T10:21:14Z						cellular_component											owl:Class	
GO:0042745	biolink:NamedThing	circadian sleep/wake cycle	The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.	got7fsn_ti														biological_process											owl:Class	
GO:0048512	biolink:NamedThing	circadian behavior	The specific behavior of an organism that recurs with a regularity of approximately 24 hours.	got7fsn_ti	circadian rhythm behavior													biological_process											owl:Class	
GO:0043703	biolink:NamedThing	photoreceptor cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0048664	biolink:NamedThing	neuron fate determination	The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0044496	biolink:NamedThing	negative regulation of blood pressure in other organism	A process by which one organism decreases the force with which blood travels through the circulatory system of another organism.	got7fsn_ti							jl	2012-02-01T02:15:28Z						biological_process											owl:Class	
GO:0106385	biolink:NamedThing	dIMP salvage	Any process which produces a dIMP from derivatives of it, without de novo synthesis.	got7fsn_ti							hjd	2021-06-11T20:03:19Z						biological_process											owl:Class	
GO:0043094	biolink:NamedThing	cellular metabolic compound salvage	Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0061409	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to freezing	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a freezing stimulus, temperatures below 0 degrees Celsius.	got7fsn_ti							dph	2012-01-12T12:11:06Z						biological_process											owl:Class	
GO:0071497	biolink:NamedThing	cellular response to freezing	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.	got7fsn_ti	ice nucleation inhibitor activity|antifreeze activity						mah	2009-12-18T02:41:02Z						biological_process											owl:Class	
GO:0006703	biolink:NamedThing	estrogen biosynthetic process	The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.	got7fsn_ti	estrogen biosynthesis|oestrogen biosynthetic process|oestrogen biosynthesis|estrogen anabolism|estrogen formation|estrogen synthesis													biological_process											owl:Class	
GO:0042638	biolink:NamedThing	exogen	The shedding phase of the hair cycle.	got7fsn_ti	hair shedding				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0044851	biolink:NamedThing	hair cycle phase	The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).		jl	2014-07-16T14:22:09Z						biological_process											owl:Class	
GO:0072254	biolink:NamedThing	metanephric glomerular mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-03-19T04:04:02Z						biological_process											owl:Class	
GO:0072209	biolink:NamedThing	metanephric mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-03-18T11:56:44Z						biological_process											owl:Class	
GO:0097122	biolink:NamedThing	cyclin A2-CDK1 complex	A protein complex consisting of cyclin A2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:42:24Z						cellular_component											owl:Class	
GO:0000307	biolink:NamedThing	cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.	got7fsn_ti	CDK holoenzyme													cellular_component											owl:Class	
GO:0018000	biolink:NamedThing	N-terminal peptidyl-tyrosine acetylation	The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine.	got7fsn_ti												RESID:AA0053		biological_process											owl:Class	
GO:0006474	biolink:NamedThing	N-terminal protein amino acid acetylation	The acetylation of the N-terminal amino acid of proteins.	got7fsn_ti	N(alpha)-terminal acetylation													biological_process											owl:Class	
GO:0044020	biolink:NamedThing	histone methyltransferase activity (H4-R3 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4.	got7fsn_ti	histone methylase activity (H4-R3 specific)|histone-arginine N-methyltransferase activity (H4-R3 specific)													molecular_function											owl:Class	
GO:0008469	biolink:NamedThing	histone-arginine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine.	got7fsn_ti	histone methyltransferase activity|histone-arginine N-methylase activity|S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity|histone protein methylase activity|nuclear protein (histone) N-methyltransferase activity|histone protein methylase I|S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity|protein methylase I activity										GO:0016276	Reactome:R-HSA-8937113|Reactome:R-HSA-5205799|Reactome:R-HSA-8936584|Reactome:R-HSA-8936608|Reactome:R-HSA-5661117|Reactome:R-HSA-5216234|Reactome:R-HSA-5205861|Reactome:R-HSA-8937022		molecular_function											owl:Class	
GO:0050810	biolink:NamedThing	regulation of steroid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	got7fsn_ti	regulation of steroid synthesis|regulation of steroid formation|regulation of steroid biosynthesis|regulation of steroid anabolism|regulation of steroidogenesis													biological_process											owl:Class	
GO:0090079	biolink:NamedThing	translation regulator activity, nucleic acid binding	Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.	got7fsn_ti							tb	2009-10-19T10:19:05Z						molecular_function											owl:Class	
GO:0045182	biolink:NamedThing	translation regulator activity	Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.	got7fsn_ti	translation factor activity													molecular_function											owl:Class	
GO:0070040	biolink:NamedThing	rRNA (adenine-C2-)-methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA.	got7fsn_ti												MetaCyc:RXN-11586|EC:2.1.1.192		molecular_function											owl:Class	
GO:0008169	biolink:NamedThing	C-methyltransferase activity	Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule.	got7fsn_ti												EC:2.1.1.-		molecular_function											owl:Class	
GO:0097504	biolink:NamedThing	Gemini of coiled bodies	Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA).	got7fsn_ti	Gems						pr	2013-09-24T15:20:12Z						cellular_component											owl:Class	
GO:0140440	biolink:NamedThing	protein-cysteine S-oleoyltransferase activity	Catalysis of the transfer of an oleoyl (systematic name, (9Z)-octadecenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18882					pg	2020-03-11T09:56:11Z				RHEA:59744		molecular_function											owl:Class	
GO:0019707	biolink:NamedThing	protein-cysteine S-acyltransferase activity	Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18882										RHEA:63372		molecular_function											owl:Class	
GO:0060736	biolink:NamedThing	prostate gland growth	The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.	got7fsn_ti							dph	2009-06-15T09:21:52Z						biological_process											owl:Class	
GO:0031695	biolink:NamedThing	alpha-2B adrenergic receptor binding	Binding to an alpha-2B adrenergic receptor.	got7fsn_ti	alpha-2B adrenergic receptor ligand													molecular_function											owl:Class	
GO:0031690	biolink:NamedThing	adrenergic receptor binding	Binding to an adrenergic receptor.	got7fsn_ti	adrenergic receptor ligand													molecular_function											owl:Class	
GO:0072573	biolink:NamedThing	tolerance induction to lipopolysaccharide	Tolerance induction directed at lipopolysaccharide antigens.	got7fsn_ti	tolerance induction to LPS|tolerance induction to endotoxin						mah	2011-02-02T03:05:19Z						biological_process											owl:Class	
GO:0045171	biolink:NamedThing	intercellular bridge	A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.	got7fsn_ti														cellular_component											owl:Class	
GO:0052080	biolink:NamedThing	modulation by symbiont of host innate immune response MAPK kinase signaling	Any process in which an organism modulates the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|modulation of defense-related host mitogen activated protein kinase-mediated signal transduction pathway by organism|modulation of defense-related host MAPK-mediated signal transduction pathway by organism|modulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/19235									GO:0052277			biological_process											owl:Class	
GO:0052031	biolink:NamedThing	modulation by symbiont of host defense response	Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	mitigation by symbiont of host defense response|pathogenesis|modulation by organism of defense response of other organism involved in symbiotic interaction										GO:0052255			biological_process											owl:Class	
GO:0071771	biolink:NamedThing	aldehyde decarbonylase activity	Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO.	got7fsn_ti	decarbonylase activity						mah	2010-04-01T12:02:50Z						molecular_function											owl:Class	
GO:0009856	biolink:NamedThing	pollination	The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion.	got7fsn_ti												Wikipedia:Pollination		biological_process											owl:Class	
GO:0048102	biolink:NamedThing	autophagic cell death	A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.	got7fsn_ti	programmed cell death by macroautophagy|autophagic death|autosis|programmed cell death by autophagy|type II programmed cell death				The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not.									biological_process											owl:Class	
GO:0012501	biolink:NamedThing	programmed cell death	A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.	got7fsn_ti	caspase-independent apoptosis|RCD|nonapoptotic programmed cell death|PCD|non-apoptotic programmed cell death|caspase-independent cell death|regulated cell death				Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.						GO:0016244	Wikipedia:Programmed_cell_death		biological_process											owl:Class	
GO:0001664	biolink:NamedThing	G protein-coupled receptor binding	Binding to a G protein-coupled receptor.	got7fsn_ti	G protein coupled receptor binding|G protein coupled receptor ligand|G-protein coupled receptor binding|G-protein-coupled receptor ligand											Reactome:R-HSA-500717		molecular_function											owl:Class	
GO:0007270	biolink:NamedThing	neuron-neuron synaptic transmission	The process of synaptic transmission from a neuron to another neuron across a synapse.	got7fsn_ti	nerve-nerve synaptic transmission													biological_process											owl:Class	
GO:0007268	biolink:NamedThing	chemical synaptic transmission	The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	got7fsn_ti	neurotransmission|signal transmission across a synapse|synaptic transmission											Wikipedia:Neurotransmission		biological_process											owl:Class	
GO:0032802	biolink:NamedThing	low-density lipoprotein particle receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti	LDL receptor catabolic process|low-density lipoprotein receptor breakdown|LDL receptor degradation|low-density lipoprotein receptor degradation|LDL receptor breakdown|low-density lipoprotein receptor catabolism|low-density lipoprotein receptor catabolic process|LDL receptor catabolism													biological_process											owl:Class	
GO:0032799	biolink:NamedThing	low-density lipoprotein receptor particle metabolic process	The chemical reactions and pathways involving low-density lipoprotein receptors.	got7fsn_ti	low-density lipoprotein receptor metabolism|LDL receptor metabolic process|low-density lipoprotein receptor metabolic process													biological_process											owl:Class	
GO:0019036	biolink:NamedThing	viral transcriptional complex	Specific locations and structures in the virus infected cell involved in transcribing the viral genome.	got7fsn_ti														cellular_component											owl:Class	
GO:0030311	biolink:NamedThing	poly-N-acetyllactosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.	got7fsn_ti	poly-N-acetyllactosamine biosynthesis|poly-N-acetyllactosamine synthesis|poly-N-acetyllactosamine anabolism|poly-N-acetyllactosamine formation													biological_process											owl:Class	
GO:0050413	biolink:NamedThing	D-alanine 2-hydroxymethyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine.	got7fsn_ti	5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase activity|2-methylserine hydroxymethyltransferase activity|D-alanine hydroxymethyltransferase activity											RHEA:10064|KEGG_REACTION:R01225|EC:2.1.2.7|MetaCyc:D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0016742	biolink:NamedThing	hydroxymethyl-, formyl- and related transferase activity	Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).	got7fsn_ti												EC:2.1.2.-		molecular_function											owl:Class	
GO:0097672	biolink:NamedThing	SCF-Pof5 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae).	got7fsn_ti	SCF-YDR306C ubiquitin ligase complex						pr	2014-10-06T10:30:10Z						cellular_component											owl:Class	
GO:0009966	biolink:NamedThing	regulation of signal transduction	Any process that modulates the frequency, rate or extent of signal transduction.	got7fsn_ti	regulation of signaling pathway|regulation of signalling pathway										GO:0035466			biological_process											owl:Class	
GO:0048754	biolink:NamedThing	branching morphogenesis of an epithelial tube	The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.	got7fsn_ti	tubulogenesis													biological_process											owl:Class	
GO:0061138	biolink:NamedThing	morphogenesis of a branching epithelium	The process in which the anatomical structures of a branched epithelium are generated and organized.	got7fsn_ti							dph	2010-05-25T09:05:34Z						biological_process											owl:Class	
GO:0070158	biolink:NamedThing	mitochondrial seryl-tRNA aminoacylation	The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0030350	biolink:NamedThing	iron-responsive element binding	Binding to an iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins.	got7fsn_ti	IRE binding													molecular_function											owl:Class	
GO:0003729	biolink:NamedThing	mRNA binding	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.	got7fsn_ti	base pairing with mRNA										GO:0000499			molecular_function											owl:Class	
GO:0072148	biolink:NamedThing	epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell.	got7fsn_ti							mah	2010-02-24T02:05:03Z						biological_process											owl:Class	
GO:0048105	biolink:NamedThing	establishment of body hair planar orientation	Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.	got7fsn_ti														biological_process											owl:Class	
GO:0048104	biolink:NamedThing	establishment of body hair or bristle planar orientation	Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project.	got7fsn_ti														biological_process											owl:Class	
GO:0002463	biolink:NamedThing	central tolerance induction to nonself antigen	Tolerance induction to nonself antigens in the central lymphoid organs.	got7fsn_ti														biological_process											owl:Class	
GO:0002508	biolink:NamedThing	central tolerance induction	Tolerance induction in the central lymphoid organs: the thymus and bone marrow.	got7fsn_ti														biological_process											owl:Class	
GO:0016004	biolink:NamedThing	phospholipase activator activity	Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0060229	biolink:NamedThing	lipase activator activity	Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0044865	biolink:NamedThing	negative regulation by virus of host cell division	Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division.	got7fsn_ti	inhibition by virus of host cell division						jl	2014-08-05T16:31:44Z						biological_process											owl:Class	
GO:0051782	biolink:NamedThing	negative regulation of cell division	Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.	got7fsn_ti	down regulation of cell division|inhibition of cell division|down-regulation of cell division|downregulation of cell division													biological_process											owl:Class	
GO:0070590	biolink:NamedThing	spore wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.	got7fsn_ti							mah	2009-04-28T01:06:10Z						biological_process											owl:Class	
GO:0042546	biolink:NamedThing	cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	got7fsn_ti	cell wall assembly													biological_process											owl:Class	
GO:0002080	biolink:NamedThing	acrosomal membrane	The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.	got7fsn_ti														cellular_component											owl:Class	
GO:0046630	biolink:NamedThing	gamma-delta T cell proliferation	The expansion of a gamma-delta T cell population by cell division.	got7fsn_ti	gamma-delta T-lymphocyte proliferation|gamma-delta T lymphocyte proliferation|gamma-delta T-cell proliferation													biological_process											owl:Class	
GO:0007209	biolink:NamedThing	phospholipase C-activating tachykinin receptor signaling pathway	The series of molecular signals generated as a consequence of a tachykinin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	activation of phospholipase C activity by tachykinin receptor signalling pathway|activation of phospholipase C activity by tachykinin receptor signaling pathway|tachykinin receptor, phospholipase C activating pathway													biological_process											owl:Class	
GO:0007217	biolink:NamedThing	tachykinin receptor signaling pathway	The series of molecular signals generated as a consequence of a tachykinin, i.e. a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2), binding to a cell surface receptor.	got7fsn_ti	tachykinin signalling pathway													biological_process											owl:Class	
GO:0009707	biolink:NamedThing	chloroplast outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope.	got7fsn_ti	chloroplast outer envelope													cellular_component											owl:Class	
GO:0031969	biolink:NamedThing	chloroplast membrane	Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.	got7fsn_ti												Wikipedia:Chloroplast_membrane		cellular_component											owl:Class	
GO:0071138	biolink:NamedThing	alpha5-beta5-fibronectin-SFRP2 complex	A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2.	got7fsn_ti	ITGA5-ITGB5-FN-1-SFRP2 complex						mah	2009-11-13T02:30:31Z						cellular_component											owl:Class	
GO:0003179	biolink:NamedThing	heart valve morphogenesis	The process in which the structure of a heart valve is generated and organized.	got7fsn_ti	heart valve remodeling|heart valve remodelling						dph	2009-10-08T11:23:48Z						biological_process											owl:Class	
GO:0043136	biolink:NamedThing	glycerol-3-phosphatase activity	Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.	got7fsn_ti												Reactome:R-HSA-8955794|MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0019752	biolink:NamedThing	carboxylic acid metabolic process	The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).	got7fsn_ti	carboxylic acid metabolism													biological_process											owl:Class	
GO:1990357	biolink:NamedThing	terminal web	An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells.	got7fsn_ti							pr	2014-04-03T14:29:59Z						cellular_component											owl:Class	
GO:0030864	biolink:NamedThing	cortical actin cytoskeleton	The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0000131	biolink:NamedThing	incipient cellular bud site	The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.	got7fsn_ti														cellular_component											owl:Class	
GO:0017197	biolink:NamedThing	N-terminal peptidyl-proline acetylation	The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline.	got7fsn_ti												RESID:AA0050		biological_process											owl:Class	
GO:0018208	biolink:NamedThing	peptidyl-proline modification	The modification of peptidyl-proline.	got7fsn_ti														biological_process											owl:Class	
GO:0000772	biolink:NamedThing	mating pheromone activity	The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted.	got7fsn_ti														molecular_function											owl:Class	
GO:0005186	biolink:NamedThing	pheromone activity	The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant.	got7fsn_ti					Also consider annotating to 'receptor agonist activity ; GO:0048018'.									molecular_function											owl:Class	
GO:0033778	biolink:NamedThing	7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+).	got7fsn_ti	HCO 12alpha-hydroxylase activity|7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity|sterol 12alpha-hydroxylase activity|7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity|CYP12											Reactome:R-HSA-193709|EC:1.14.14.139|KEGG_REACTION:R04826|MetaCyc:1.14.13.95-RXN|Reactome:R-HSA-193845|Reactome:R-HSA-192157|RHEA:10504		molecular_function											owl:Class	
GO:0016533	biolink:NamedThing	protein kinase 5 complex	A protein complex that has protein serine/threonine kinase activity; in mammals composed of catalytic subunit CDK5 and regulatory subunits CDK5R1 or CDK5R2. Contrary to its gene symbol, CDK5 is not cyclin-dependent.	got7fsn_ti	cyclin-dependent protein kinase 5 holoenzyme complex													cellular_component											owl:Class	
GO:1902554	biolink:NamedThing	serine/threonine protein kinase complex	A protein complex which is capable of protein serine/threonine kinase activity.	got7fsn_ti	PDR16 complex homodimer|PDR16 complex dimer				An example is IRE1 in S. cerevisiae (UniProt ID P32361) in PMID:18191223 (inferred from direct assay).		bhm	2013-12-06T16:06:12Z						cellular_component											owl:Class	
GO:0010464	biolink:NamedThing	regulation of mesenchymal cell proliferation	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	got7fsn_ti														biological_process											owl:Class	
GO:0042127	biolink:NamedThing	regulation of cell population proliferation	Any process that modulates the frequency, rate or extent of cell proliferation.	got7fsn_ti	regulation of cell proliferation													biological_process											owl:Class	
GO:0051728	biolink:NamedThing	cell cycle switching, mitotic to meiotic cell cycle	The process in which a cell switches cell cycle mode from mitotic to meiotic division.	got7fsn_ti	conversion to meiosis|initiation of meiosis|initiation of meiotic cell cycle|entry into meiosis|conversion to meiotic cell cycle|cell cycle switching, mitosis to meiosis|meiotic entry|entry into meiotic cell cycle										GO:0042061			biological_process											owl:Class	
GO:0060184	biolink:NamedThing	cell cycle switching	The process in which a cell switches cell cycle mode.	got7fsn_ti														biological_process											owl:Class	
GO:0033699	biolink:NamedThing	DNA 5'-adenosine monophosphate hydrolase activity	Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.	got7fsn_ti	DNA adenylate hydrolysis activity|DNA de-adenylation|DNA 5'-adenylate hydrolase activity|DNA deadenylation|AMP-removal activity													molecular_function											owl:Class	
GO:0035312	biolink:NamedThing	5'-3' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0003096	biolink:NamedThing	renal sodium ion transport	The directed movement of sodium ions (Na+) by the renal system.	got7fsn_ti														biological_process											owl:Class	
GO:0003014	biolink:NamedThing	renal system process	A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).	got7fsn_ti	excretory system process|kidney system process													biological_process											owl:Class	
GO:0018265	biolink:NamedThing	GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GPI anchor formation via N-asparaginyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-asparaginyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-asparaginyl-glycosylphosphatidylinositolethanolamine											RESID:AA0158		biological_process											owl:Class	
GO:0021549	biolink:NamedThing	cerebellum development	The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	got7fsn_ti														biological_process											owl:Class	
GO:0000109	biolink:NamedThing	nucleotide-excision repair complex	Any complex formed of proteins that act in nucleotide-excision repair.	got7fsn_ti	UvrBC complex|UvrB-UvrC complex				Note that process information is included in the term and definition for the purpose of describing and distinguishing the complex.									cellular_component											owl:Class	
GO:0002469	biolink:NamedThing	myeloid dendritic cell antigen processing and presentation	The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0006179	biolink:NamedThing	guanosine salvage	Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis.	got7fsn_ti	guanine, xanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0006166	biolink:NamedThing	purine ribonucleoside salvage	Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.	got7fsn_ti												MetaCyc:P121-PWY		biological_process											owl:Class	
GO:0048875	biolink:NamedThing	chemical homeostasis within a tissue	Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0038191	biolink:NamedThing	neuropilin binding	Binding to a member of the neuropilin family.	got7fsn_ti	Nrp binding|Nrp ligand|neuropilin-binding						bf	2013-08-01T16:11:33Z						molecular_function											owl:Class	
GO:0061246	biolink:NamedThing	establishment or maintenance of bipolar cell polarity regulating cell shape	Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.	got7fsn_ti							dph	2010-08-23T09:46:01Z						biological_process											owl:Class	
GO:0071963	biolink:NamedThing	establishment or maintenance of cell polarity regulating cell shape	Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.	got7fsn_ti							mah	2011-06-21T03:47:21Z						biological_process											owl:Class	
GO:0098992	biolink:NamedThing	neuronal dense core vesicle	A dense core vesicle (granule) that is part of a neuron.  These vesicles typically contain neuropeptides.  They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.	got7fsn_ti														cellular_component											owl:Class	
GO:0031045	biolink:NamedThing	dense core granule	Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.	got7fsn_ti	dense core vesicle											NIF_Subcellular:sao772007592		cellular_component											owl:Class	
GO:0070980	biolink:NamedThing	biphenyl catabolic process	The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).	got7fsn_ti	biphenyl breakdown|biphenyl degradation|biphenyl catabolism						mah	2009-10-27T11:24:59Z						biological_process											owl:Class	
GO:1990397	biolink:NamedThing	queuosine salvage	Any process which produces queuosine from derivatives of it, without de novo synthesis.	got7fsn_ti							pr	2014-06-10T14:56:12Z						biological_process											owl:Class	
GO:0008616	biolink:NamedThing	queuosine biosynthetic process	The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.	got7fsn_ti	queuosine biosynthesis|queuosine formation|queuosine synthesis|queuosine anabolism													biological_process											owl:Class	
GO:0046555	biolink:NamedThing	acetylxylan esterase activity	Catalysis of the deacetylation of xylans and xylo-oligosaccharides.	got7fsn_ti												MetaCyc:3.1.1.72-RXN|EC:3.1.1.72		molecular_function											owl:Class	
GO:0071091	biolink:NamedThing	alpha1-beta1 integrin-tissue transglutaminase complex	A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.	got7fsn_ti	ITGA1-ITGB1-TGM2 complex						mah	2009-11-06T04:46:44Z						cellular_component											owl:Class	
GO:0036334	biolink:NamedThing	epidermal stem cell homeostasis	Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.	got7fsn_ti							bf	2012-09-05T10:21:23Z						biological_process											owl:Class	
GO:0005979	biolink:NamedThing	regulation of glycogen biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	got7fsn_ti	regulation of glycogen synthesis|regulation of glycogen anabolism|regulation of glycogen formation|regulation of glycogen biosynthesis													biological_process											owl:Class	
GO:0070873	biolink:NamedThing	regulation of glycogen metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.	got7fsn_ti	regulation of glycogen metabolism						mah	2009-08-20T02:44:53Z						biological_process											owl:Class	
GO:0036120	biolink:NamedThing	cellular response to platelet-derived growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.	got7fsn_ti	cellular response to PDGF stimulus						bf	2012-02-20T02:49:02Z						biological_process											owl:Class	
GO:0106307	biolink:NamedThing	protein threonine phosphatase activity	Catalysis of the reaction: protein threonine phosphate + H2O = protein threonine + phosphate.	got7fsn_ti							hjd	2020-09-09T19:38:50Z				RHEA:47004|EC:3.1.3.16		molecular_function											owl:Class	
GO:0004722	biolink:NamedThing	protein serine/threonine phosphatase activity	Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.	got7fsn_ti	protein phosphatase type 4 activity|phosphatase II|protein phosphatase type 4, intrinsic catalyst activity|protein phosphatase type 2B activity|phosphatase SP|protein phosphatase type 1, intrinsic catalyst activity|protein D phosphatase|phosphatase I|calcineurin|magnesium-dependent protein serine/threonine phosphatase activity|protein phosphatase type 2C activity|serine/threonine specific protein phosphatase activity|phosphopyruvate dehydrogenase phosphatase|phosphospectrin phosphatase|phosphatase 2A|phosphatase H-II|phosphatase 2B|phosphatase IB|protein phosphatase type 2A activity|phosphatase C-II|BCKDH phosphatase|Aspergillus awamori acid protein phosphatase|protein phosphatase type 1 activity|phosphatase III|phosphatase IV|protein phosphatase type 2B, intrinsic catalyst activity|3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase|HMG-CoA reductase phosphatase|protein phosphatase X|polycation modulated (PCM-) phosphatase|casein phosphatase|branched-chain alpha-keto acid dehydrogenase phosphatase|protein phosphatase type 2A, intrinsic catalyst activity										GO:0000158|GO:0030361|GO:0030357|GO:0030358|GO:0008598|GO:0008600|GO:0000163|GO:0004724|GO:0015071|GO:0030360	Reactome:R-HSA-3002811|Reactome:R-HSA-201790|Reactome:R-HSA-5692754|Reactome:R-HSA-199959|Reactome:R-HSA-5694421|Reactome:R-HSA-209055|Reactome:R-HSA-9660538|Reactome:R-HSA-163568|Reactome:R-HSA-9619449|Reactome:R-HSA-2187401|Reactome:R-HSA-6792863|Reactome:R-HSA-4419948|Reactome:R-HSA-5672961|Reactome:R-HSA-429730|Reactome:R-HSA-1638821|Reactome:R-HSA-5675431|Reactome:R-HSA-3601585|Reactome:R-HSA-2995388|Reactome:R-HSA-1295632|Reactome:R-HSA-74948|Reactome:R-HSA-9619467|Reactome:R-HSA-201787|EC:3.1.3.16|Reactome:R-HSA-5683405|Reactome:R-HSA-5693153|Reactome:R-HSA-8948139|Reactome:R-HSA-9619430|Reactome:R-HSA-9660536|Reactome:R-HSA-199425|Reactome:R-HSA-5687758|Reactome:R-HSA-5679206|Reactome:R-HSA-4088141|Reactome:R-HSA-5675433|Reactome:R-HSA-5672957|Reactome:R-HSA-9686524|Reactome:R-HSA-6811504|Reactome:R-HSA-9658445|Reactome:R-HSA-380949		molecular_function											owl:Class	
GO:0030743	biolink:NamedThing	rRNA (adenosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine.	got7fsn_ti	rRNA adenosine 2'-methylase activity|ribosomal ribonucleate adenosine 2'-methyltransferase activity|RNA-pentose methylase activity|S-adenosyl-L-methionine:rRNA (adenosine-2'-O)-methyltransferase activity|thiostrepton-resistance methylase activity											MetaCyc:2.1.1.66-RXN|RHEA:43212|EC:2.1.1.230		molecular_function											owl:Class	
GO:0016433	biolink:NamedThing	rRNA (adenine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine.	got7fsn_ti														molecular_function											owl:Class	
GO:0031230	biolink:NamedThing	intrinsic component of cell outer membrane	The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to cell outer membrane													cellular_component											owl:Class	
GO:0031224	biolink:NamedThing	intrinsic component of membrane	The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.	got7fsn_ti	intrinsic to membrane				Note that proteins intrinsic to membranes cannot be removed without disrupting the membrane, e.g. by detergent.									cellular_component											owl:Class	
GO:0097155	biolink:NamedThing	fasciculation of sensory neuron axon	The collection of sensory neuron axons into a bundle of rods, known as a fascicle.	got7fsn_ti							pr	2011-09-16T09:17:34Z						biological_process											owl:Class	
GO:0007413	biolink:NamedThing	axonal fasciculation	The collection of axons into a bundle of rods, known as a fascicle.	got7fsn_ti	fasciculation of neuron													biological_process											owl:Class	
GO:0018345	biolink:NamedThing	protein palmitoylation	The covalent attachment of a palmitoyl group to a protein.	got7fsn_ti	protein amino acid palmitoylation										GO:0018349|GO:0018318			biological_process											owl:Class	
GO:0005871	biolink:NamedThing	kinesin complex	Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.	got7fsn_ti														cellular_component											owl:Class	
GO:0005875	biolink:NamedThing	microtubule associated complex	Any multimeric complex connected to a microtubule.	got7fsn_ti														cellular_component											owl:Class	
GO:0050962	biolink:NamedThing	detection of light stimulus involved in sensory perception	The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.	got7fsn_ti	sensory perception, sensory detection of light stimulus|sensory transduction of light stimulus during sensory perception|sensory transduction of light stimulus|sensory detection of light stimulus|sensory perception, sensory transduction of light stimulus|sensory detection of light stimulus during sensory perception													biological_process											owl:Class	
GO:0052672	biolink:NamedThing	CTP:geranylgeraniol kinase activity	Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP.	got7fsn_ti	CTP:geranylgeraniol phosphotransferase activity						ai	2011-04-11T03:26:04Z				EC:2.7.1.216|MetaCyc:RXN-11629		molecular_function											owl:Class	
GO:0052671	biolink:NamedThing	geranylgeraniol kinase activity	Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate.	got7fsn_ti	geranylgeraniol phosphotransferase activity						ai	2011-04-11T03:18:44Z						molecular_function											owl:Class	
GO:0043438	biolink:NamedThing	acetoacetic acid metabolic process	The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH.	got7fsn_ti	3-oxobutanoic acid metabolic process|beta-ketobutyric acid metabolic process|beta ketobutyric acid metabolism|beta ketobutyric acid metabolic process|beta-ketobutyric acid metabolism|acetoacetate metabolism|acetoacetate metabolic process|3-oxobutanoate metabolic process|diacetic acid metabolic process|diacetic acid metabolism|3-oxobutanoate metabolism|acetoacetic acid metabolism|3-oxobutanoic acid metabolism													biological_process											owl:Class	
GO:0046459	biolink:NamedThing	short-chain fatty acid metabolic process	The chemical reactions and pathways involving fatty acids with a chain length of less than C6.	got7fsn_ti	short-chain fatty acid metabolism													biological_process											owl:Class	
GO:0018767	biolink:NamedThing	2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate.	got7fsn_ti												UM-BBD_reactionID:r0399		molecular_function											owl:Class	
GO:0016823	biolink:NamedThing	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.	got7fsn_ti												EC:3.7.1.-		molecular_function											owl:Class	
GO:0060143	biolink:NamedThing	positive regulation of syncytium formation by plasma membrane fusion	Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0051130	biolink:NamedThing	positive regulation of cellular component organization	Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.	got7fsn_ti	upregulation of cell organization|stimulation of cell organization|up-regulation of cell organization|up regulation of cell organization|positive regulation of cell organisation|activation of cell organization|positive regulation of cellular component organization and biogenesis													biological_process											owl:Class	
GO:0033514	biolink:NamedThing	L-lysine catabolic process to acetyl-CoA via L-pipecolate	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.	got7fsn_ti	L-lysine breakdown to acetyl-CoA via L-pipecolate|L-lysine degradation to acetyl-CoA via L-pipecolate											MetaCyc:PWY-5283		biological_process											owl:Class	
GO:0019474	biolink:NamedThing	L-lysine catabolic process to acetyl-CoA	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA.	got7fsn_ti	L-lysine degradation to acetyl-CoA|L-lysine breakdown to acetyl-CoA													biological_process											owl:Class	
GO:0106296	biolink:NamedThing	D-series resolvin biosynthetic process	The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid.	got7fsn_ti							hjd	2020-08-25T13:48:32Z						biological_process											owl:Class	
GO:0106295	biolink:NamedThing	resolvin biosynthetic process	The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.	got7fsn_ti					Resolvin biosynthesis is a combination of oxidation, reduction and hydrolysis reactions involving lipoxygenases and cyclooxygenases.		hjd	2020-08-25T13:46:15Z						biological_process											owl:Class	
GO:0004151	biolink:NamedThing	dihydroorotase activity	Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+).	got7fsn_ti	carbamoylaspartic dehydrase activity|dihydroorotate hydrolase activity|(S)-dihydroorotate amidohydrolase activity|DHOase activity											MetaCyc:DIHYDROOROT-RXN|RHEA:24296|EC:3.5.2.3|KEGG_REACTION:R01993|Reactome:R-HSA-73571		molecular_function											owl:Class	
GO:0016812	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.	got7fsn_ti												Reactome:R-HSA-70906|EC:3.5.2.-		molecular_function											owl:Class	
GO:0044594	biolink:NamedThing	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+.	got7fsn_ti							jl	2012-04-26T04:49:13Z				RHEA:24612		molecular_function											owl:Class	
GO:0004303	biolink:NamedThing	estradiol 17-beta-dehydrogenase activity	Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+.	got7fsn_ti	20alpha-hydroxysteroid dehydrogenase|estradiol dehydrogenase activity|17beta,20alpha-hydroxysteroid dehydrogenase activity|estradiol-17beta:NAD(P)+ 17-oxidoreductase activity|17beta-hydroxysteroid dehydrogenase activity|17-beta-hydroxysteroid dehydrogenase activity|estrogen 17-oxidoreductase activity|17-beta-HSD activity|17-beta-estradiol dehydrogenase activity|estradiol 17beta-dehydrogenase activity|17beta-HSD|17beta-estradiol dehydrogenase activity											Reactome:R-HSA-804969|Reactome:R-HSA-5693390|Reactome:R-HSA-6810594|EC:1.1.1.62|Reactome:R-HSA-8862137|Reactome:R-HSA-5696822|MetaCyc:ESTRADIOL-17-BETA-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0002015	biolink:NamedThing	regulation of systemic arterial blood pressure by atrial baroreceptor feedback	A process that controls blood pressure by sensing the amount of stretch occurring in the atria.	got7fsn_ti	atrial control of blood pressure|atrial reflex|atrial baroreceptor regulation of systemic arterial blood pressure|atrial low pressure baroreceptor regulation of blood pressure													biological_process											owl:Class	
GO:0003015	biolink:NamedThing	heart process	A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	got7fsn_ti	cardiac process													biological_process											owl:Class	
GO:0031077	biolink:NamedThing	post-embryonic camera-type eye development	The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure.	got7fsn_ti	post-embryonic camera-style eye development													biological_process											owl:Class	
GO:0047324	biolink:NamedThing	phosphoenolpyruvate-glycerone phosphotransferase activity	Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.	got7fsn_ti	phosphoenolpyruvate:glycerone phosphotransferase activity											KEGG_REACTION:R01012|MetaCyc:2.7.1.121-RXN|RHEA:18381|EC:2.7.1.121		molecular_function											owl:Class	
GO:0014886	biolink:NamedThing	transition between slow and fast fiber	The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.	got7fsn_ti	transition slow-fast fibre|transition between slow and fast fibre|transition slow-fast fiber													biological_process											owl:Class	
GO:0014733	biolink:NamedThing	regulation of skeletal muscle adaptation	Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.	got7fsn_ti	regulation of skeletal muscle plasticity													biological_process											owl:Class	
GO:0048316	biolink:NamedThing	seed development	The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.	got7fsn_ti														biological_process											owl:Class	
GO:0007414	biolink:NamedThing	axonal defasciculation	Separation of axons away from a bundle of axons known as a fascicle.	got7fsn_ti	defasciculation of neuron													biological_process											owl:Class	
GO:0008038	biolink:NamedThing	neuron recognition	The process in which a neuronal cell in a multicellular organism interprets its surroundings.	got7fsn_ti	neuronal cell recognition													biological_process											owl:Class	
GO:0035488	biolink:NamedThing	cytosine/thymine mispair binding	Binding to a double-stranded DNA region containing a C/T mispair.	got7fsn_ti	C/T mispair binding|thymine/cytosine mispair binding|T/C mispair binding						bf	2010-04-23T10:57:13Z						molecular_function											owl:Class	
GO:0030983	biolink:NamedThing	mismatched DNA binding	Binding to a double-stranded DNA region containing one or more mismatches.	got7fsn_ti	mispair binding|mispaired DNA binding										GO:0032134			molecular_function											owl:Class	
GO:0045736	biolink:NamedThing	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.	got7fsn_ti														biological_process											owl:Class	
GO:0045786	biolink:NamedThing	negative regulation of cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.	got7fsn_ti	negative regulation of progression through cell cycle|downregulation of progression through cell cycle|inhibition of progression through cell cycle|negative regulation of cell cycle progression|down-regulation of progression through cell cycle|down regulation of progression through cell cycle													biological_process											owl:Class	
GO:0034727	biolink:NamedThing	piecemeal microautophagy of the nucleus	Degradation of a cell nucleus by lysosomal microautophagy.	got7fsn_ti	PMN													biological_process											owl:Class	
GO:0016237	biolink:NamedThing	lysosomal microautophagy	The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0061276	biolink:NamedThing	mesonephric proximal tubule morphogenesis	The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.	got7fsn_ti							dph	2010-09-02T01:11:02Z						biological_process											owl:Class	
GO:0061240	biolink:NamedThing	mesonephric nephron tubule morphogenesis	The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.	got7fsn_ti							dph	2010-08-19T03:09:26Z						biological_process											owl:Class	
GO:0003087	biolink:NamedThing	positive regulation of the force of heart contraction by neuronal epinephrine	The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction.	got7fsn_ti	increased force of heart contraction by neuronal epinephrine|increased force of heart contraction by epinephrine released from the nerve endings|positive regulation of heart contraction by neuronal epinephrine|positive regulation of heart contraction by adrenaline|increased force of heart contraction by neuronal adrenaline													biological_process											owl:Class	
GO:0003059	biolink:NamedThing	positive regulation of the force of heart contraction by epinephrine	The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.	got7fsn_ti	adrenaline cardiac inotropy|epinephrine cardiac inotropy|adrenaline regulation of the strength of heart muscle contraction|positive regulation of heart contraction by adrenaline|increased force of heart contraction by epinephrine|positive regulation of heart contraction by epinephrine													biological_process											owl:Class	
GO:0015668	biolink:NamedThing	type III site-specific deoxyribonuclease activity	Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.	got7fsn_ti	type III restriction enzyme activity											EC:3.1.21.5|MetaCyc:3.1.21.5-RXN		molecular_function											owl:Class	
GO:0016888	biolink:NamedThing	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.	got7fsn_ti	endodeoxyribonuclease activity, producing 5' phosphomonoesters											EC:3.1.21.-|Reactome:R-HSA-912368		molecular_function											owl:Class	
GO:0021888	biolink:NamedThing	hypothalamus gonadotrophin-releasing hormone neuron development	The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell.	got7fsn_ti	hypothalamus gonadotropin-releasing hormone neuron development													biological_process											owl:Class	
GO:0021884	biolink:NamedThing	forebrain neuron development	The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0033958	biolink:NamedThing	DNA-deoxyinosine glycosylase activity	Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine.	got7fsn_ti	deoxyribonucleic acid glycosylase activity|hypoxanthine-DNA glycosylase activity|DNA-deoxyinosine deoxyribohydrolase activity|DNA-deoxyinosine glycosidase activity|DNA(hypoxanthine) glycohydrolase activity											EC:3.2.2.15|MetaCyc:3.2.2.15-RXN		molecular_function											owl:Class	
GO:1990324	biolink:NamedThing	collagen type XXVI trimer	A collagen homotrimer of alpha1(XXVI) chains.	got7fsn_ti							bhm	2014-03-16T23:02:35Z						cellular_component											owl:Class	
GO:0001410	biolink:NamedThing	chlamydospore formation	The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans.	got7fsn_ti	chlamydospore development										GO:0055027			biological_process											owl:Class	
GO:0048468	biolink:NamedThing	cell development	The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti	terminal differentiation													biological_process											owl:Class	
GO:0031418	biolink:NamedThing	L-ascorbic acid binding	Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.	got7fsn_ti	L-ascorbate binding|vitamin C binding													molecular_function											owl:Class	
GO:0019842	biolink:NamedThing	vitamin binding	Binding to a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	got7fsn_ti														molecular_function											owl:Class	
GO:0043637	biolink:NamedThing	puromycin metabolic process	The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.	got7fsn_ti	puromycin metabolism													biological_process											owl:Class	
GO:0016999	biolink:NamedThing	antibiotic metabolic process	The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.	got7fsn_ti	antibiotic metabolism													biological_process											owl:Class	
GO:1990374	biolink:NamedThing	Kir2 inward rectifier potassium channel complex	A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells.	got7fsn_ti	Kir2.1 complex				An example of this is Kcnj2 in mouse (P35561) in PMID:16834334 (inferred from direct assay).		bhm	2014-04-25T15:29:15Z						cellular_component											owl:Class	
GO:1902937	biolink:NamedThing	inward rectifier potassium channel complex	A protein complex which is capable of inward rectifier potassium channel activity.	got7fsn_ti					An example of this is Kcnj2 in mouse (P35561) in PMID:16834334 (inferred from direct assay).		bhm	2014-04-25T15:18:41Z						cellular_component											owl:Class	
GO:0060693	biolink:NamedThing	regulation of branching involved in salivary gland morphogenesis	Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.	got7fsn_ti							dph	2009-06-08T01:14:44Z						biological_process											owl:Class	
GO:2000027	biolink:NamedThing	regulation of animal organ morphogenesis	Any process that modulates the frequency, rate or extent of animal organ morphogenesis.	got7fsn_ti	regulation of histogenesis and organogenesis						tb	2010-08-05T11:26:27Z						biological_process											owl:Class	
GO:0050681	biolink:NamedThing	androgen receptor binding	Binding to an androgen receptor.	got7fsn_ti	AR binding													molecular_function											owl:Class	
GO:0007075	biolink:NamedThing	positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	got7fsn_ti	activation of transcription on exit from mitosis, from RNA polymerase III promoter|activation of transcription on exit from mitosis, from Pol III promoter													biological_process											owl:Class	
GO:0044470	biolink:NamedThing	envenomation resulting in negative regulation of blood coagulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism.	got7fsn_ti							jl	2012-01-19T01:32:48Z						biological_process											owl:Class	
GO:0044483	biolink:NamedThing	envenomation resulting in impairment of hemostasis in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism.	got7fsn_ti	envenomation, impairing hemostasis in other organism|envenomation resulting in negative regulation of hemostasis in other organism						jl	2012-01-19T03:15:56Z						biological_process											owl:Class	
GO:0052495	biolink:NamedThing	occlusion by organism of vascular system in other organism involved in symbiotic interaction	The process in which an organism reduces the flow of fluid within its second organism's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant, where the two organisms are in a symbiotic interaction.	got7fsn_ti	occlusion by organism of vascular system in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0052185	biolink:NamedThing	modification of structure of other organism involved in symbiotic interaction	The process in which an organism effects a change in an anatomical part or cellular component of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modification of structure of other organism during symbiotic interaction													biological_process											owl:Class	
GO:0046523	biolink:NamedThing	S-methyl-5-thioribose-1-phosphate isomerase activity	Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate.	got7fsn_ti	MTR-1-P isomerase activity|5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity|1-phospho-5'-S-methylthioribose isomerase activity|S-methyl-5-thio-alpha-D-ribose-1-phosphate aldose-ketose-isomerase activity|S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase activity|1-PMTR isomerase activity|S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity|S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase activity|methylthioribose 1-phosphate isomerase activity|5-methylthioribose-1-phosphate isomerase activity											MetaCyc:5.3.1.23-RXN|Reactome:R-HSA-1299507|Reactome:R-HSA-1237096|RHEA:19989|EC:5.3.1.23|KEGG_REACTION:R04420		molecular_function											owl:Class	
GO:0102608	biolink:NamedThing	tetracenomycin B3 8-O-methyl transferase activity	Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine  <=> tetracenomycin E + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-15435		molecular_function											owl:Class	
GO:0070341	biolink:NamedThing	fat cell proliferation	The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.	got7fsn_ti	adipocyte proliferation|adipose cell proliferation													biological_process											owl:Class	
GO:0045924	biolink:NamedThing	regulation of female receptivity	Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances.	got7fsn_ti	female receptivity										GO:0060181			biological_process											owl:Class	
GO:0060180	biolink:NamedThing	female mating behavior	The specific behavior of a female organism that is associated with reproduction.	got7fsn_ti														biological_process											owl:Class	
GO:0097697	biolink:NamedThing	tRNA 5-carboxymethoxyuridine methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosylmethionine to a 5-carboxymethoxy-modified uridine residue in a tRNA molecule.	got7fsn_ti							pr	2016-01-07T10:36:46Z						molecular_function											owl:Class	
GO:0016300	biolink:NamedThing	tRNA (uracil) methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule.	got7fsn_ti	tRNA (uridine) methyltransferase activity				Note that the methyl donor is usually S-adenosyl-L-methionine, but there is at least one exception (see GO:0030698).						GO:0016431			molecular_function											owl:Class	
GO:0098509	biolink:NamedThing	sensory perception of humidity	The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti	hygrosensory perception				Note, this is not classified under 'detection of chemical stimulus' as there are various potential mechanisms of hygroperception including detection of mechanical stimulus.		dos	2013-09-25T13:52:27Z						biological_process											owl:Class	
GO:0008656	biolink:NamedThing	cysteine-type endopeptidase activator activity involved in apoptotic process	Binds to and increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.	got7fsn_ti	caspase activator activity				Examples of this are 1) granzymes that may bind to initiator caspases and cleave them, and 2) already active caspases, e.g. caspase 9, that cleave effector caspases.							Reactome:R-HSA-449073|Reactome:R-HSA-205117		molecular_function											owl:Class	
GO:0016505	biolink:NamedThing	peptidase activator activity involved in apoptotic process	Binds to and increases the activity of a peptidase that is involved in the apoptotic process.	got7fsn_ti	apoptotic protease activator activity													molecular_function											owl:Class	
GO:0061226	biolink:NamedThing	proximal/distal pattern formation involved in mesonephric nephron development	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).	got7fsn_ti							dph	2010-08-19T02:10:25Z						biological_process											owl:Class	
GO:0072047	biolink:NamedThing	proximal/distal pattern formation involved in nephron development	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).	got7fsn_ti	proximal/distal nephron patterning|proximal-distal pattern formation involved in nephron development						mah	2010-01-25T03:30:48Z						biological_process											owl:Class	
GO:0090557	biolink:NamedThing	establishment of endothelial intestinal barrier	The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.	got7fsn_ti							tb	2013-10-29T15:08:27Z						biological_process											owl:Class	
GO:0061028	biolink:NamedThing	establishment of endothelial barrier	The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.	got7fsn_ti							dph	2010-02-09T09:26:59Z						biological_process											owl:Class	
GO:0047391	biolink:NamedThing	alkylglycerophosphoethanolamine phosphodiesterase activity	Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate.	got7fsn_ti	1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase activity|lysophospholipase D activity											EC:3.1.4.39|RHEA:15965|MetaCyc:3.1.4.39-RXN		molecular_function											owl:Class	
GO:0086042	biolink:NamedThing	cardiac muscle cell-cardiac muscle cell adhesion	The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules.	got7fsn_ti	cardiomyocyte-cardiomyocyte adhesion						tb	2011-11-11T04:06:25Z						biological_process											owl:Class	
GO:0036093	biolink:NamedThing	germ cell proliferation	The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.	got7fsn_ti							bf	2012-01-17T04:06:27Z						biological_process											owl:Class	
GO:0022403	biolink:NamedThing	cell cycle phase	One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0080049	biolink:NamedThing	L-gulono-1,4-lactone dehydrogenase activity	Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.	got7fsn_ti												MetaCyc:RXN-1439		molecular_function											owl:Class	
GO:0016632	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome.	got7fsn_ti												EC:1.3.2.-		molecular_function											owl:Class	
GO:0005215	biolink:NamedThing	transporter activity	Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.	got7fsn_ti	carrier				Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules.						GO:0005478	Reactome:R-HSA-178215|Reactome:R-HSA-168313|EC:7.-.-.-		molecular_function											owl:Class	
GO:0030034	biolink:NamedThing	microvillar actin bundle assembly	Assembly of the parallel bundle of actin filaments at the core of a microvillus.	got7fsn_ti														biological_process											owl:Class	
GO:0051017	biolink:NamedThing	actin filament bundle assembly	The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.	got7fsn_ti	actin cable formation|actin bundling activity|actin cable assembly										GO:0045011			biological_process											owl:Class	
GO:0090447	biolink:NamedThing	glycerol-3-phosphate 2-O-acyltransferase activity	Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate.	got7fsn_ti							tb	2012-08-31T09:23:12Z						molecular_function											owl:Class	
GO:0061581	biolink:NamedThing	corneal epithelial cell migration	The orderly movement of a corneal  epithelial cell from one site to another, often during the development of a multicellular organism.	got7fsn_ti							dph	2013-12-23T07:28:29Z						biological_process											owl:Class	
GO:0010631	biolink:NamedThing	epithelial cell migration	The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.	got7fsn_ti														biological_process											owl:Class	
GO:0090664	biolink:NamedThing	response to high population density	Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area.	got7fsn_ti	response to crowding						tb	2015-10-21T16:00:30Z						biological_process											owl:Class	
GO:0043794	biolink:NamedThing	formate dehydrogenase (coenzyme F420) activity	Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420.	got7fsn_ti	formate dehydrogenase (F420) activity											EC:1.2.99.-		molecular_function											owl:Class	
GO:0046877	biolink:NamedThing	regulation of saliva secretion	Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0021503	biolink:NamedThing	neural fold bending	The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.	got7fsn_ti														biological_process											owl:Class	
GO:0061288	biolink:NamedThing	mesonephric capsule specification	The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti							dph	2010-09-02T01:56:20Z						biological_process											owl:Class	
GO:0072130	biolink:NamedThing	renal capsule specification	The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti							mah	2010-02-22T02:12:34Z						biological_process											owl:Class	
GO:0019197	biolink:NamedThing	phosphoenolpyruvate-dependent sugar phosphotransferase complex	Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system).	got7fsn_ti														cellular_component											owl:Class	
GO:0061088	biolink:NamedThing	regulation of sequestering of zinc ion	Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.	got7fsn_ti							dph	2010-04-26T01:38:53Z						biological_process											owl:Class	
GO:0034010	biolink:NamedThing	sulfolactate sulfo-lyase activity	Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite.	got7fsn_ti	3-sulfolactate bisulfite-lyase activity|3-sulfolactate bisulfite-lyase (pyruvate-forming) activity|SuyAB|Suy											KEGG_REACTION:R07633|EC:4.4.1.24|MetaCyc:4.4.1.24-RXN|RHEA:21428		molecular_function											owl:Class	
GO:0016846	biolink:NamedThing	carbon-sulfur lyase activity	Catalysis of the elimination of hydrogen sulfide or substituted H2S.	got7fsn_ti	carbon-sulphur lyase activity											Reactome:R-HSA-1614567|EC:4.4.-.-		molecular_function											owl:Class	
GO:0031247	biolink:NamedThing	actin rod assembly	The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules.	got7fsn_ti	actin rod formation													biological_process											owl:Class	
GO:0007015	biolink:NamedThing	actin filament organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.	got7fsn_ti	regulation of actin filament localization|actin filament organisation													biological_process											owl:Class	
GO:0007107	biolink:NamedThing	membrane addition at site of cytokinesis	Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.	got7fsn_ti	cytokinesis, membrane recruitment/generation													biological_process											owl:Class	
GO:0061024	biolink:NamedThing	membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.	got7fsn_ti	cellular membrane organisation|cellular membrane organization|single-organism membrane organization|membrane organisation|membrane organization and biogenesis						jl	2010-02-08T02:43:11Z			GO:0016044|GO:0044802			biological_process											owl:Class	
GO:0098564	biolink:NamedThing	trans-Golgi network transport vesicle lumen	The volume enclosed within the membrane of a trans-Golgi network transport vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0098566	biolink:NamedThing	transport vesicle lumen	The volume enclosed within the membrane of a transport vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0004483	biolink:NamedThing	mRNA (nucleoside-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.	got7fsn_ti	mRNA (adenosine-2'-O-)-methyltransferase activity|S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase activity|messenger RNA (nucleoside-2'-)-methyltransferase activity|messenger ribonucleate nucleoside 2'-methyltransferase activity											Reactome:R-HSA-9694499|Reactome:R-HSA-9684033|Reactome:R-HSA-9694521|EC:2.1.1.57|Reactome:R-HSA-9694721|Reactome:R-HSA-9684032|Reactome:R-HSA-9684030|MetaCyc:2.1.1.57-RXN		molecular_function											owl:Class	
GO:0008171	biolink:NamedThing	O-methyltransferase activity	Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.	got7fsn_ti												Reactome:R-HSA-5629218|Reactome:R-HSA-5578717|Reactome:R-HSA-5629237|Reactome:R-HSA-6790907|Reactome:R-HSA-5629203|EC:2.1.1.-		molecular_function											owl:Class	
GO:0120116	biolink:NamedThing	glucagon processing	The formation of mature glucagon by proteolysis of the precursor proglucagon.	got7fsn_ti							krc	2017-11-08T19:31:42Z						biological_process											owl:Class	
GO:0016486	biolink:NamedThing	peptide hormone processing	The generation of a mature peptide hormone by posttranslational processing of a prohormone.	got7fsn_ti														biological_process											owl:Class	
GO:0003868	biolink:NamedThing	4-hydroxyphenylpyruvate dioxygenase activity	Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2.	got7fsn_ti	p-hydroxyphenylpyruvate oxidase activity|p-hydroxyphenylpyruvate dioxygenase activity|4-hydroxyphenylpyruvic acid dioxygenase activity|p-hydroxyphenylpyruvate hydroxylase activity|p-hydroxyphenylpyruvic hydroxylase activity|4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)|p-hydroxyphenylpyruvic acid hydroxylase activity|p-hydroxyphenylpyruvic oxidase activity|4-hydroxyphenylpyruvate hydroxylase activity											Reactome:R-HSA-71163|EC:1.13.11.27|UM-BBD_reactionID:r0298|MetaCyc:4-HYDROXYPHENYLPYRUVATE-DIOXYGENASE-RXN|RHEA:16189		molecular_function											owl:Class	
GO:0034644	biolink:NamedThing	cellular response to UV	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.	got7fsn_ti	cellular response to ultraviolet radiation stimulus|cellular response to UV radiation stimulus|cellular response to ultraviolet light stimulus|cellular response to UV light stimulus													biological_process											owl:Class	
GO:0070338	biolink:NamedThing	5'-flap-structured DNA binding	Binding to a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.	got7fsn_ti														molecular_function											owl:Class	
GO:0070336	biolink:NamedThing	flap-structured DNA binding	Binding to a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0090567	biolink:NamedThing	reproductive shoot system development	The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure.	got7fsn_ti							tb	2014-04-25T15:42:03Z						biological_process											owl:Class	
GO:0034198	biolink:NamedThing	cellular response to amino acid starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.	got7fsn_ti	general amino acid control response|GAAC response													biological_process											owl:Class	
GO:1990928	biolink:NamedThing	response to amino acid starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.	got7fsn_ti							sl	2016-02-18T00:18:23Z						biological_process											owl:Class	
GO:0051290	biolink:NamedThing	protein heterotetramerization	The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.	got7fsn_ti	protein heterotetramer assembly|protein heterotetramer formation|protein heterotetramer biosynthesis|protein heterotetramer biosynthetic process													biological_process											owl:Class	
GO:0051262	biolink:NamedThing	protein tetramerization	The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.	got7fsn_ti	protein tetramer assembly|protein tetramer biosynthetic process|protein tetramer formation|protein tetramer biosynthesis													biological_process											owl:Class	
GO:0060487	biolink:NamedThing	lung epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.	got7fsn_ti	pulmonary epithelial cell differentiation													biological_process											owl:Class	
GO:0007589	biolink:NamedThing	body fluid secretion	The controlled release of a fluid by a cell or tissue in an animal.	got7fsn_ti														biological_process											owl:Class	
GO:0052624	biolink:NamedThing	2-phytyl-1,4-naphthoquinone methyltransferase activity	Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+.	got7fsn_ti	S-adenosyl-L-methionine:2-phytyl-1,4-naphthoquinone methyltransferase activity|salicylic acid methyltransferase activity|S-adenosyl-L-methionine:demethylphylloquinone methyltransferase activity|salicylate methyltransferase activity|S-adenosyl-L-methionine:salicylate carboxyl methyltransferase activity|demethylphylloquinone methyltransferase activity|SA methyltransferase activity						ai	2010-08-26T12:00:06Z				KEGG_REACTION:R06859|MetaCyc:RXN-6723|MetaCyc:RXN-7569		molecular_function											owl:Class	
GO:0090472	biolink:NamedThing	dibasic protein processing	Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein.	got7fsn_ti							tb	2012-10-01T10:39:26Z						biological_process											owl:Class	
GO:0016485	biolink:NamedThing	protein processing	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.	got7fsn_ti	protein maturation by peptide bond cleavage|peptidolysis during protein maturation|protein maturation by proteolysis|protein maturation by peptide bond hydrolysis										GO:0051605			biological_process											owl:Class	
GO:0043825	biolink:NamedThing	succinylornithine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + N(2)-succinyl-L-ornithine = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.	got7fsn_ti	succinyl ornithine transaminase activity|AstC|N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|N2-succinylornithine 5-aminotransferase activity|2-N-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|succinylornithine aminotransferase activity|N(2)-succinylornithine 5-aminotransferase activity|SOAT|succinyl-ornithine transaminase activity											MetaCyc:SUCCORNTRANSAM-RXN|KEGG_REACTION:R04217|RHEA:16953|EC:2.6.1.81		molecular_function											owl:Class	
GO:0102298	biolink:NamedThing	selenocystathione synthase activity	Catalysis of the reaction: L-selenocysteine  + O-phosphonato-L-homoserine = hydrogenphosphate + L-selenocystathionine.	got7fsn_ti												MetaCyc:RXN-12728		molecular_function											owl:Class	
GO:0003203	biolink:NamedThing	endocardial cushion morphogenesis	The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	got7fsn_ti							dph	2009-10-08T01:43:22Z						biological_process											owl:Class	
GO:0072132	biolink:NamedThing	mesenchyme morphogenesis	The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells.	got7fsn_ti							mah	2010-02-22T02:17:15Z						biological_process											owl:Class	
GO:0035651	biolink:NamedThing	AP-3 adaptor complex binding	Binding to an AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).	got7fsn_ti							bf	2011-01-25T10:59:36Z						molecular_function											owl:Class	
GO:0044877	biolink:NamedThing	protein-containing complex binding	Binding to a macromolecular complex.	got7fsn_ti	macromolecular complex binding|protein complex binding						jl	2014-12-16T11:38:58Z			GO:0032403			molecular_function											owl:Class	
GO:0006781	biolink:NamedThing	succinyl-CoA pathway	The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.	got7fsn_ti	biosynthesis of protoporphyrin IX via succinyl CoA|succinyl CoA pathway|biosynthetic process of protoporphyrin IX via succinyl-CoA|biosynthetic process of protoporphyrin IX via succinyl CoA|biosynthesis of protoporphyrin IX via succinyl-CoA													biological_process											owl:Class	
GO:0006779	biolink:NamedThing	porphyrin-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.	got7fsn_ti	porphyrin synthesis|porphyrin biosynthesis|porphyrin anabolism|porphyrin biosynthetic process|porphyrin formation													biological_process											owl:Class	
GO:0018799	biolink:NamedThing	4-hydroxybenzoate decarboxylase activity	Catalysis of the reaction: 4-hydroxybenzoate + H(+) = CO(2) + phenol.	got7fsn_ti	p-hydroxybenzoate decarboxylase activity|4-hydroxybenzoate carboxy-lyase (phenol-forming)|4-hydroxybenzoate carboxy-lyase activity											EC:4.1.1.61|MetaCyc:4-HYDROXYBENZOATE-DECARBOXYLASE-RXN|RHEA:10876|KEGG_REACTION:R01238|UM-BBD_reactionID:r0159		molecular_function											owl:Class	
GO:0071032	biolink:NamedThing	nuclear mRNA surveillance of mRNP export	The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.	got7fsn_ti	nuclear mRNA quality control of mRNAs in aberrant mRNPs|nuclear mRNA catabolic process of mRNAs in aberrant mRNPs						krc	2009-07-28T04:31:57Z						biological_process											owl:Class	
GO:0071028	biolink:NamedThing	nuclear mRNA surveillance	The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus.	got7fsn_ti	nuclear mRNA quality control|nuclear aberrant mRNA catabolic process						krc	2009-07-28T04:14:29Z						biological_process											owl:Class	
GO:0045503	biolink:NamedThing	dynein light chain binding	Binding to a light chain of the dynein complex.	got7fsn_ti														molecular_function											owl:Class	
GO:1990814	biolink:NamedThing	DNA/DNA annealing activity	An activity that faciliates the formation of a complementary double-stranded DNA molecule.	got7fsn_ti	DNA reannealing activity	https://github.com/geneontology/go-ontology/issues/2161					vw	2015-07-29T12:35:03Z						molecular_function											owl:Class	
GO:0140666	biolink:NamedThing	annealing activity	An activity that facilitates the formation of a complementary double-stranded polynucleotide molecule.	got7fsn_ti	renaturation	https://github.com/geneontology/go-ontology/issues/21614					pr	2014-06-13T10:18:43Z			GO:0097617			molecular_function											owl:Class	
GO:0070199	biolink:NamedThing	establishment of protein localization to chromosome	The directed movement of a protein to a specific location on a chromosome.	got7fsn_ti	establishment of protein localisation to chromosome													biological_process											owl:Class	
GO:0106331	biolink:NamedThing	sialate 4-O-acetylesterase activity	Catalysis of the reaction: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate.	got7fsn_ti							hjd	2020-09-30T19:40:24Z				EC:3.1.1.53|RHEA:25564		molecular_function											owl:Class	
GO:0001681	biolink:NamedThing	sialate O-acetylesterase activity	Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.	got7fsn_ti	N-acyl-O-acetylneuraminate O-acetylhydrolase activity|N-acetylneuraminate acetyltransferase activity|sialate 9(4)-O-acetylesterase activity											MetaCyc:SIALATE-O-ACETYLESTERASE-RXN|EC:3.1.1.53		molecular_function											owl:Class	
GO:0006595	biolink:NamedThing	polyamine metabolic process	The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.	got7fsn_ti	polyamine metabolism													biological_process											owl:Class	
GO:0008294	biolink:NamedThing	calcium- and calmodulin-responsive adenylate cyclase activity	Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.	got7fsn_ti	calcium/calmodulin-responsive adenylate cyclase activity|calcium- and calmodulin-responsive adenylyl cyclase activity											Reactome:R-HSA-111930|Reactome:R-HSA-442715		molecular_function											owl:Class	
GO:0004016	biolink:NamedThing	adenylate cyclase activity	Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.	got7fsn_ti	adenylyl cyclase activity|cAMP generating peptide activity|ATP pyrophosphate-lyase activity|ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity|ATP diphosphate-lyase (cyclizing) activity|adenylylcyclase activity|adenyl cyclase activity|3',5'-cyclic AMP synthetase activity											Reactome:R-HSA-5211224|Reactome:R-HSA-170676|MetaCyc:ADENYLATECYC-RXN|Reactome:R-HSA-392129|RHEA:15389|EC:4.6.1.1|Reactome:R-HSA-164377|Reactome:R-HSA-5610727|Reactome:R-HSA-381607		molecular_function											owl:Class	
GO:0102262	biolink:NamedThing	tRNA-dihydrouridine16 synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) <=> H+ + a uracil16 in tRNA + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-12454		molecular_function											owl:Class	
GO:0017150	biolink:NamedThing	tRNA dihydrouridine synthase activity	Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor.	got7fsn_ti												RHEA:23624|MetaCyc:RXN0-1281|Reactome:R-HSA-6782296		molecular_function											owl:Class	
GO:0002159	biolink:NamedThing	desmosome assembly	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.	got7fsn_ti					Desmosomes link two cells together; hemidesmosomes attach one cell to the extracellular matrix.		hjd	2010-02-09T10:46:30Z						biological_process											owl:Class	
GO:0002934	biolink:NamedThing	desmosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.	got7fsn_ti							hjd	2012-05-08T02:59:08Z						biological_process											owl:Class	
GO:0032158	biolink:NamedThing	septin band	A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.	got7fsn_ti														cellular_component											owl:Class	
GO:0001551	biolink:NamedThing	ovarian follicle endowment	Association of oocytes with supporting epithelial granulosa cells to form primordial follicles.	got7fsn_ti														biological_process											owl:Class	
GO:0019771	biolink:NamedThing	high-affinity IgG receptor activity	Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	high affinity Fc receptor activity|high affinity IgG receptor activity													molecular_function											owl:Class	
GO:0019770	biolink:NamedThing	IgG receptor activity	Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0090360	biolink:NamedThing	platelet-derived growth factor production	The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		tb	2010-07-12T10:32:27Z						biological_process											owl:Class	
GO:0018993	biolink:NamedThing	somatic sex determination	The determination of sex and sexual phenotypes in an organism's soma.	got7fsn_ti														biological_process											owl:Class	
GO:0007530	biolink:NamedThing	sex determination	Any process that establishes and transmits the specification of sexual status of an individual organism.	got7fsn_ti												Wikipedia:Sex-determination_system		biological_process											owl:Class	
GO:0008050	biolink:NamedThing	female courtship behavior	The behavior of a female, for the purpose of attracting a sexual partner.	got7fsn_ti	female courtship behaviour													biological_process											owl:Class	
GO:0002357	biolink:NamedThing	defense response to tumor cell	Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism.	got7fsn_ti														biological_process											owl:Class	
GO:0002347	biolink:NamedThing	response to tumor cell	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.	got7fsn_ti														biological_process											owl:Class	
GO:0050321	biolink:NamedThing	tau-protein kinase activity	Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein.	got7fsn_ti	ATP:tau-protein O-phosphotransferase activity|tau-tubulin kinase activity|tau-protein kinase I activity|protein tau kinase activity|[Tau protein] kinase activity|tau-protein kinase II activity|tau kinase activity|cdk5/p20|TPK II|brain protein kinase PK40erk activity|TPK I|glycogen synthase kinase-3beta activity|TTK|tau protein kinase activity|CDK5/p23|STK31|TPK|GSK											EC:2.7.11.26|MetaCyc:TAU-PROTEIN-KINASE-RXN		molecular_function											owl:Class	
GO:0045619	biolink:NamedThing	regulation of lymphocyte differentiation	Any process that modulates the frequency, rate or extent of lymphocyte differentiation.	got7fsn_ti	regulation of lymphocyte development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0099519	biolink:NamedThing	dense core granule cytoskeletal transport	The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.	got7fsn_ti	dense core granule cytoskeletal transport|dense core vesicle cytoskeletal trafficking													biological_process											owl:Class	
GO:1901950	biolink:NamedThing	dense core granule transport	The directed movement a dense core granule within a cell.	got7fsn_ti	dense core vesicle transport				goslim_synapse		pr	2013-02-19T13:00:52Z						biological_process											owl:Class	
GO:0071008	biolink:NamedThing	U2-type post-mRNA release spliceosomal complex	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.	got7fsn_ti	GT-AG post-mRNA release spliceosomal complex|mammalian U2-type spliceosomal complex I|U2/U5/U6 snRNP complex|major post-mRNA release spliceosomal complex|U2/U5/U6 tri-snRNP complex						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0071014	biolink:NamedThing	post-mRNA release spliceosomal complex	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5.	got7fsn_ti	mammalian spliceosomal complex I						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0030312	biolink:NamedThing	external encapsulating structure	A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.	got7fsn_ti					The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'.									cellular_component											owl:Class	
GO:0031266	biolink:NamedThing	TRAIL death-inducing signaling complex	A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor.	got7fsn_ti	TRAIL DISC|TRAIL death-inducing signalling complex													cellular_component											owl:Class	
GO:0031264	biolink:NamedThing	death-inducing signaling complex	A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.	got7fsn_ti	DISC|death receptor-induced signalling complex|death receptor-induced signaling complex|DISC protein complex|death-inducing signalling complex				Gene products that may be annotated to this term include: 1) ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer); 2) signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10.							Wikipedia:Death-inducing_signaling_complex		cellular_component											owl:Class	
GO:0005828	biolink:NamedThing	kinetochore microtubule	Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.	got7fsn_ti	pole-to-kinetochore microtubule													cellular_component											owl:Class	
GO:0005876	biolink:NamedThing	spindle microtubule	Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.	got7fsn_ti														cellular_component											owl:Class	
GO:0009861	biolink:NamedThing	jasmonic acid and ethylene-dependent systemic resistance	The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.	got7fsn_ti	jasmonic acid/ethylene-dependent systemic resistance|jasmonic acid and ethene-dependent systemic resistance													biological_process											owl:Class	
GO:0009611	biolink:NamedThing	response to wounding	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.	got7fsn_ti	physiological response to wounding										GO:0002245			biological_process											owl:Class	
GO:1902187	biolink:NamedThing	negative regulation of viral release from host cell	Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host cell.	got7fsn_ti	down-regulation of viral shedding|downregulation of viral exit|down-regulation of viral exit|inhibition of viral release from host cell|down regulation of release of virus from host|negative regulation of release of virus from host|negative regulation of viral shedding|negative regulation of viral release|down regulation of viral shedding|negative regulation of viral exit|downregulation of release of virus from host|down regulation of viral release|down regulation of viral exit|inhibition of viral exit|down-regulation of release of virus from host|down-regulation of viral release|down regulation of viral release from host cell|downregulation of viral shedding|down-regulation of viral release from host cell|inhibition of viral release|downregulation of viral release from host cell|inhibition of viral shedding|inhibition of release of virus from host|downregulation of viral release						ss	2013-06-04T03:54:08Z						biological_process											owl:Class	
GO:0008889	biolink:NamedThing	glycerophosphodiester phosphodiesterase activity	Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.	got7fsn_ti	IgD-binding protein D|glycerophosphoryl diester phosphodiesterase activity|gene hpd protein|glycerophosphodiester glycerophosphohydrolase activity											RHEA:12969|Reactome:R-HSA-1483116|EC:3.1.4.46|MetaCyc:GLYCPDIESTER-RXN|Reactome:R-HSA-1483107		molecular_function											owl:Class	
GO:0003232	biolink:NamedThing	bulbus arteriosus development	The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.	got7fsn_ti							dph	2009-10-13T11:05:36Z						biological_process											owl:Class	
GO:0003205	biolink:NamedThing	cardiac chamber development	The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.	got7fsn_ti							dph	2009-10-13T09:11:18Z						biological_process											owl:Class	
GO:0071253	biolink:NamedThing	connexin binding	Binding to a connexin, any of a group of related proteins that assemble to form gap junctions.	got7fsn_ti							mah	2009-12-04T10:07:54Z						molecular_function											owl:Class	
GO:0030922	biolink:NamedThing	peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.	got7fsn_ti												RESID:AA0365		biological_process											owl:Class	
GO:0018251	biolink:NamedThing	peptidyl-tyrosine dehydrogenation	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues.	got7fsn_ti					See also the biological process terms 'peptide cross-linking via L-seryl-5-imidazolinone glycine ; GO:0018252' and 'peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine ; GO:0019729'.							RESID:AA0183		biological_process											owl:Class	
GO:0051250	biolink:NamedThing	negative regulation of lymphocyte activation	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.	got7fsn_ti	down-regulation of lymphocyte activation|down regulation of lymphocyte activation|downregulation of lymphocyte activation|inhibition of lymphocyte activation													biological_process											owl:Class	
GO:0002695	biolink:NamedThing	negative regulation of leukocyte activation	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.	got7fsn_ti	negative regulation of immune cell activation|down regulation of leukocyte activation|downregulation of leukocyte activation|negative regulation of leucocyte activation|inhibition of leukocyte activation|down-regulation of leukocyte activation													biological_process											owl:Class	
GO:2001158	biolink:NamedThing	positive regulation of proline catabolic process to glutamate	Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate.	got7fsn_ti	positive regulation of proline degradation to glutamate|positive regulation of proline breakdown to glutamate|positive regulation of proline oxidation						mcc	2011-10-25T08:54:50Z						biological_process											owl:Class	
GO:0033243	biolink:NamedThing	positive regulation of cellular amine catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.	got7fsn_ti	positive regulation of amine degradation|positive regulation of amine breakdown|positive regulation of amine catabolism													biological_process											owl:Class	
GO:0048050	biolink:NamedThing	post-embryonic eye morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight.	got7fsn_ti											GO:0048051			biological_process											owl:Class	
GO:0048592	biolink:NamedThing	eye morphogenesis	The process in which the anatomical structures of the eye are generated and organized.	got7fsn_ti											GO:0048748			biological_process											owl:Class	
GO:0005919	biolink:NamedThing	pleated septate junction	A septate junction in which regular arrays of electron-dense septae span the intermembrane space.	got7fsn_ti	pleated desmosome													cellular_component											owl:Class	
GO:0005918	biolink:NamedThing	septate junction	A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods.	got7fsn_ti	septate desmosome											NIF_Subcellular:sao427941916		cellular_component											owl:Class	
GO:0021797	biolink:NamedThing	forebrain anterior/posterior pattern specification	The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.	got7fsn_ti	forebrain anterior-posterior pattern specification													biological_process											owl:Class	
GO:0009952	biolink:NamedThing	anterior/posterior pattern specification	The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	got7fsn_ti	anterior/posterior pattern formation													biological_process											owl:Class	
GO:0008960	biolink:NamedThing	phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity	Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose.	got7fsn_ti	phosphoglycerol transferase I|phosphoglycerol transferase activity|phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity|oligosaccharide glycerophosphotransferase activity											MetaCyc:PGLYCEROLTRANSI-RXN|EC:2.7.8.20		molecular_function											owl:Class	
GO:0014843	biolink:NamedThing	growth factor dependent regulation of skeletal muscle satellite cell proliferation	Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.	got7fsn_ti														biological_process											owl:Class	
GO:0014842	biolink:NamedThing	regulation of skeletal muscle satellite cell proliferation	Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0004064	biolink:NamedThing	arylesterase activity	Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.	got7fsn_ti	aryl-ester hydrolase|A-esterase activity|paraoxonase activity|aromatic esterase											EC:3.1.1.2|UM-BBD_reactionID:r0757|MetaCyc:ARYLESTERASE-RXN|RHEA:17309		molecular_function											owl:Class	
GO:0021778	biolink:NamedThing	oligodendrocyte cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0021780	biolink:NamedThing	glial cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0031498	biolink:NamedThing	chromatin disassembly	The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA.	got7fsn_ti	chromatin maintenance													biological_process											owl:Class	
GO:0006333	biolink:NamedThing	chromatin assembly or disassembly	The formation or destruction of chromatin structures.	got7fsn_ti	chromatin assembly/disassembly													biological_process											owl:Class	
GO:0034508	biolink:NamedThing	centromere complex assembly	The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.	got7fsn_ti	centromere assembly|chromosome, centromeric region assembly|centromere organization													biological_process											owl:Class	
GO:0065004	biolink:NamedThing	protein-DNA complex assembly	The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.	got7fsn_ti	DNA-protein complex assembly													biological_process											owl:Class	
GO:0000249	biolink:NamedThing	C-22 sterol desaturase activity	Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.	got7fsn_ti														molecular_function											owl:Class	
GO:0070704	biolink:NamedThing	sterol desaturase activity	Catalysis of the introduction of a double bond into a sterol molecule.	got7fsn_ti							mah	2009-06-08T03:53:44Z						molecular_function											owl:Class	
GO:0021903	biolink:NamedThing	rostrocaudal neural tube patterning	The process in which the neural tube is divided into specific regions along the rostrocaudal axis.	got7fsn_ti	anterior-posterior neural tube patterning													biological_process											owl:Class	
GO:0003099	biolink:NamedThing	positive regulation of the force of heart contraction by chemical signal	Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.	got7fsn_ti	positive regulation of the force of heart muscle contraction by chemical signal													biological_process											owl:Class	
GO:0003057	biolink:NamedThing	regulation of the force of heart contraction by chemical signal	The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.	got7fsn_ti	chemical cardiac inotropy|regulation of the force of heart muscle contraction by chemical signal													biological_process											owl:Class	
GO:0071759	biolink:NamedThing	IgX immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti					Note that an IgX immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgX is found in amphibians.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0019814	biolink:NamedThing	immunoglobulin complex	A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	antibody				Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.									cellular_component											owl:Class	
GO:0004919	biolink:NamedThing	interleukin-9 receptor activity	Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-9R|IL-9 receptor activity													molecular_function											owl:Class	
GO:0004896	biolink:NamedThing	cytokine receptor activity	Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL receptor|hematopoietin/interferon-class (D200-domain) cytokine receptor activity|interleukin receptor activity										GO:0004907			molecular_function											owl:Class	
GO:0008023	biolink:NamedThing	transcription elongation factor complex	Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.	got7fsn_ti														cellular_component											owl:Class	
GO:0035794	biolink:NamedThing	positive regulation of mitochondrial membrane permeability	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.	got7fsn_ti	mitochondrial membrane permeability transition|mitochondrial membrane permeabilization|positive regulation of transport across mitochondrial membrane|MPT|mitochondrial permeability transition						bf	2011-04-11T01:44:06Z						biological_process											owl:Class	
GO:1905710	biolink:NamedThing	positive regulation of membrane permeability	Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane.	got7fsn_ti							hbye	2016-11-18T13:10:53Z						biological_process											owl:Class	
GO:0016048	biolink:NamedThing	detection of temperature stimulus	The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.	got7fsn_ti	perception of temperature|detection of temperature|detection of thermal stimulus													biological_process											owl:Class	
GO:0009581	biolink:NamedThing	detection of external stimulus	The series of events in which an external stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of external stimulus													biological_process											owl:Class	
GO:0034979	biolink:NamedThing	NAD-dependent protein deacetylase activity	Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD.	got7fsn_ti												Reactome:R-HSA-9667952|Reactome:R-HSA-5685953|Reactome:R-HSA-5688289|Reactome:R-HSA-9620532|Reactome:R-HSA-5211239|Reactome:R-HSA-5688294|Reactome:R-HSA-3371467		molecular_function											owl:Class	
GO:0033558	biolink:NamedThing	protein deacetylase activity	Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate.	got7fsn_ti												Reactome:R-HSA-8952069|Reactome:R-HSA-9626962|Reactome:R-HSA-5693092		molecular_function											owl:Class	
GO:0070875	biolink:NamedThing	positive regulation of glycogen metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.	got7fsn_ti	positive regulation of glycogen metabolism						mah	2009-08-20T02:53:55Z						biological_process											owl:Class	
GO:0010604	biolink:NamedThing	positive regulation of macromolecule metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti														biological_process											owl:Class	
GO:0002561	biolink:NamedThing	basophil degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.	got7fsn_ti														biological_process											owl:Class	
GO:0043299	biolink:NamedThing	leukocyte degranulation	The regulated exocytosis of secretory granules by a leukocyte.	got7fsn_ti	immune cell degranulation|immune cell granule exocytosis|leukocyte granule exocytosis|leucocyte degranulation													biological_process											owl:Class	
GO:1990466	biolink:NamedThing	protein autosumoylation	The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.	got7fsn_ti	protein auto-sumoylation|protein self-sumoylation						se	2014-08-25T22:37:21Z						biological_process											owl:Class	
GO:0061108	biolink:NamedThing	seminal vesicle epithelium development	The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-04-30T10:19:54Z						biological_process											owl:Class	
GO:0098029	biolink:NamedThing	icosahedral viral capsid, spike	A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell.	got7fsn_ti							bm	2012-07-19T14:37:11Z						cellular_component											owl:Class	
GO:0044423	biolink:NamedThing	virion component	Any constituent part of a virion, a complete fully infectious extracellular virus particle.	got7fsn_ti	virion part|virion|complete virus particle				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.						GO:0019012	Wikipedia:Virus		cellular_component											owl:Class	
GO:0060068	biolink:NamedThing	vagina development	The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0102338	biolink:NamedThing	3-oxo-lignoceronyl-CoA synthase activity	Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + carbon dioxide + coenzyme A.	got7fsn_ti												MetaCyc:RXN-13297|RHEA:36507		molecular_function											owl:Class	
GO:0006334	biolink:NamedThing	nucleosome assembly	The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.	got7fsn_ti	histone chaperone|nucleosome modeling													biological_process											owl:Class	
GO:0042698	biolink:NamedThing	ovulation cycle	The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.	got7fsn_ti														biological_process											owl:Class	
GO:0048757	biolink:NamedThing	pigment granule maturation	Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.	got7fsn_ti														biological_process											owl:Class	
GO:0003918	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.	got7fsn_ti	deoxyribonucleate topoisomerase|DNA topoisomerase II activity|DNA topoisomerase (ATP-hydrolysing)|DNA topoisomerase type II activity|DNA topoisomerase IV activity|deoxyribonucleic topoisomerase activity|topoisomerase II|topoisomerase|type II DNA topoisomerase activity|DNA topoisomerase II										GO:0061505	EC:5.6.2.2|MetaCyc:5.99.1.3-RXN|Wikipedia:Type_II_topoisomerase		molecular_function											owl:Class	
GO:0018717	biolink:NamedThing	9-phenanthrol glycosyltransferase activity	Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O.	got7fsn_ti												UM-BBD_reactionID:r0511		molecular_function											owl:Class	
GO:0019112	biolink:NamedThing	phenanthrol glycosyltransferase activity	Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O.	got7fsn_ti														molecular_function											owl:Class	
GO:0033738	biolink:NamedThing	methylenetetrahydrofolate reductase (ferredoxin) activity	Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.	got7fsn_ti	5-methyltetrahydrofolate:ferredoxin oxidoreductase activity|5,10-methylenetetrahydrofolate reductase activity											RHEA:14229|EC:1.5.7.1|MetaCyc:RXN-5061		molecular_function											owl:Class	
GO:0033694	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	got7fsn_ti												EC:1.5.7.-		molecular_function											owl:Class	
GO:0047408	biolink:NamedThing	alkenylglycerophosphocholine hydrolase activity	Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde.	got7fsn_ti	1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase activity|lysoplasmalogenase activity											RHEA:22544|MetaCyc:3.3.2.2-RXN|EC:3.3.2.2		molecular_function											owl:Class	
GO:0032181	biolink:NamedThing	dinucleotide repeat insertion binding	Binding to a double-stranded DNA region containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.	got7fsn_ti														molecular_function											owl:Class	
GO:0032139	biolink:NamedThing	dinucleotide insertion or deletion binding	Binding to a double-stranded DNA region containing a dinucleotide insertion or deletion.	got7fsn_ti	dinucleotide insertion binding													molecular_function											owl:Class	
GO:0051237	biolink:NamedThing	maintenance of RNA location	Any process in which RNA is maintained in a location and prevented from moving elsewhere.	got7fsn_ti	maintenance of RNA localization|RNA retention													biological_process											owl:Class	
GO:0051235	biolink:NamedThing	maintenance of location	Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.	got7fsn_ti	maintenance of localization|retention|storage|sequestering													biological_process											owl:Class	
GO:0030058	biolink:NamedThing	amine dehydrogenase activity	Catalysis of the reaction: an aliphatic amine + an acceptor (A) + H2O = an aldehyde + a reduced acceptor (AH2) + NH4+.	got7fsn_ti	primary-amine dehydrogenase activity|amine: (acceptor) oxidoreductase (deaminating)|methylamine dehydrogenase activity|primary-amine:acceptor oxidoreductase (deaminating)|MADH activity	https://github.com/geneontology/go-ontology/issues/21650										UM-BBD_enzymeID:e0058|RHEA:51128		molecular_function											owl:Class	
GO:0071226	biolink:NamedThing	cellular response to molecule of fungal origin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.	got7fsn_ti	cellular response to fungus associated molecule						mah	2009-12-03T01:50:01Z						biological_process											owl:Class	
GO:0102195	biolink:NamedThing	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysinium(1+) + ATP <=> UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-D-lysine + ADP + hydrogenphosphate + H+.	got7fsn_ti												EC:6.3.2.37|MetaCyc:RXN-12042|RHEA:25273		molecular_function											owl:Class	
GO:0060643	biolink:NamedThing	epithelial cell differentiation involved in mammary gland bud morphogenesis	The process in which a cell of the mammary placode becomes a cell of the mammary gland bud.	got7fsn_ti							dph	2009-05-29T07:58:13Z						biological_process											owl:Class	
GO:0060644	biolink:NamedThing	mammary gland epithelial cell differentiation	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.	got7fsn_ti							dph	2009-05-29T08:03:07Z						biological_process											owl:Class	
GO:0047613	biolink:NamedThing	aconitate decarboxylase activity	Catalysis of the reaction: cis-aconitate + H(+) = CO(2) + itaconate.	got7fsn_ti	cis-aconitate carboxy-lyase activity|CAD activity|cis-aconitic decarboxylase activity|cis-aconitate carboxy-lyase (itaconate-forming)											KEGG_REACTION:R02243|MetaCyc:ACONITATE-DECARBOXYLASE-RXN|EC:4.1.1.6|RHEA:15253		molecular_function											owl:Class	
GO:0110121	biolink:NamedThing	gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body.	got7fsn_ti							kmv	2018-07-27T15:49:05Z						biological_process											owl:Class	
GO:1990735	biolink:NamedThing	gamma-tubulin complex localization to mitotic spindle pole body	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body.	got7fsn_ti	gamma-tubulin complex localisation to mitotic spindle pole body|establishment and maintenance of gamma-tubulin complex localization to mitotic spindle pole body|gamma-tubulin complex localization to mitotic SPB						mah	2015-04-29T14:40:20Z						biological_process											owl:Class	
GO:0071109	biolink:NamedThing	superior temporal gyrus development	The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.	got7fsn_ti							mah	2009-11-12T02:19:23Z						biological_process											owl:Class	
GO:0042331	biolink:NamedThing	phototaxis	The directed movement of a motile cell or organism in response to light.	got7fsn_ti	phototactic behaviour|phototactic behavior|taxis in response to light										GO:0046953	Wikipedia:Phototaxis		biological_process											owl:Class	
GO:0008743	biolink:NamedThing	L-threonine 3-dehydrogenase activity	Catalysis of the reaction: L-threonine + NAD(+) = L-2-amino-3-oxobutanoate + CO(2) + NADH.	got7fsn_ti	L-threonine dehydrogenase activity|L-threonine:NAD+ oxidoreductase activity|threonine dehydrogenase activity|threonine 3-dehydrogenase activity											EC:1.1.1.103|KEGG_REACTION:R01465|MetaCyc:THREODEHYD-RXN|Reactome:R-HSA-6798667|RHEA:13161		molecular_function											owl:Class	
GO:0047121	biolink:NamedThing	isoquinoline 1-oxidoreductase activity	Catalysis of the reaction: A + H(2)O + isoquinoline = AH(2) + isoquinolin-1(2H)-one.	got7fsn_ti	isoquinoline:acceptor 1-oxidoreductase (hydroxylating)											KEGG_REACTION:R05151|RHEA:11588|MetaCyc:1.3.99.16-RXN|EC:1.3.99.16		molecular_function											owl:Class	
GO:0090258	biolink:NamedThing	negative regulation of mitochondrial fission	Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.	got7fsn_ti	negative regulation of mitochondrial division						tb	2010-02-03T04:05:32Z						biological_process											owl:Class	
GO:0004555	biolink:NamedThing	alpha,alpha-trehalase activity	Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.	got7fsn_ti	alpha,alpha-trehalose glucohydrolase activity											MetaCyc:TREHALA-RXN|Reactome:R-HSA-188985|RHEA:20868|EC:3.2.1.28		molecular_function											owl:Class	
GO:0015927	biolink:NamedThing	trehalase activity	Catalysis of the hydrolysis of trehalose or a trehalose derivative.	got7fsn_ti												MetaCyc:TREHALA-RXN|RHEA:32675		molecular_function											owl:Class	
GO:2000830	biolink:NamedThing	positive regulation of parathyroid hormone secretion	Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion.	got7fsn_ti	positive regulation of parathormone secretion|positive regulation of PTH secretion|positive regulation of parathyrin secretion						bf	2011-07-26T08:38:00Z						biological_process											owl:Class	
GO:0051240	biolink:NamedThing	positive regulation of multicellular organismal process	Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.	got7fsn_ti	stimulation of multicellular organismal process|activation of multicellular organismal process|up-regulation of multicellular organismal process|up regulation of multicellular organismal process|upregulation of multicellular organismal process													biological_process											owl:Class	
GO:0006564	biolink:NamedThing	L-serine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.	got7fsn_ti	L-serine formation|L-serine synthesis|L-serine anabolism|L-serine biosynthesis											MetaCyc:SERSYN-PWY		biological_process											owl:Class	
GO:0009070	biolink:NamedThing	serine family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.	got7fsn_ti	serine family amino acid synthesis|serine family amino acid anabolism|serine family amino acid biosynthesis|serine family amino acid formation													biological_process											owl:Class	
GO:0070973	biolink:NamedThing	protein localization to endoplasmic reticulum exit site	A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.	got7fsn_ti	protein localisation to endoplasmic reticulum exit site|protein localization to ER exit site						mah	2009-10-02T12:45:41Z						biological_process											owl:Class	
GO:0070972	biolink:NamedThing	protein localization to endoplasmic reticulum	A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.	got7fsn_ti	protein localization in endoplasmic reticulum|protein localisation in endoplasmic reticulum|protein localization in ER						mah	2009-10-02T12:43:34Z						biological_process											owl:Class	
GO:0018805	biolink:NamedThing	benzylsuccinate synthase activity	Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate.	got7fsn_ti	benzylsuccinate fumarate-lyase (toluene-forming)|benzylsuccinate fumarate-lyase activity											EC:4.1.99.11|UM-BBD_enzymeID:e0259|RHEA:10416|MetaCyc:RXN-863|KEGG_REACTION:R05598		molecular_function											owl:Class	
GO:0004859	biolink:NamedThing	phospholipase inhibitor activity	Binds to and stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0055102	biolink:NamedThing	lipase inhibitor activity	Binds to and stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0072102	biolink:NamedThing	glomerulus morphogenesis	The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.	got7fsn_ti							mah	2010-02-10T02:32:09Z						biological_process											owl:Class	
GO:0030912	biolink:NamedThing	response to deep water	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle.	got7fsn_ti					Note that this term should not be confused with 'response to flooding ; GO:0009413'; which refers to immersion in water on a shorter time scale.									biological_process											owl:Class	
GO:0009415	biolink:NamedThing	response to water	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.	got7fsn_ti	response to water stimulus													biological_process											owl:Class	
GO:0005869	biolink:NamedThing	dynactin complex	A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach.	got7fsn_ti														cellular_component											owl:Class	
GO:0007483	biolink:NamedThing	genital disc morphogenesis	The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut.	got7fsn_ti	genital disc metamorphosis													biological_process											owl:Class	
GO:0007560	biolink:NamedThing	imaginal disc morphogenesis	The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.	got7fsn_ti	imaginal disc metamorphosis										GO:0007452			biological_process											owl:Class	
GO:0003347	biolink:NamedThing	epicardial cell to mesenchymal cell transition	A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium.	got7fsn_ti							dph	2009-12-01T11:05:39Z						biological_process											owl:Class	
GO:0001837	biolink:NamedThing	epithelial to mesenchymal transition	A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti	epithelial-mesenchymal transition|EMT|mesenchymal cell differentiation from epithelial cell													biological_process											owl:Class	
GO:0031780	biolink:NamedThing	corticotropin hormone receptor binding	Binding to a corticotropin hormone receptor.	got7fsn_ti	adrenocorticotropin hormone receptor binding|ACTH receptor binding|adrenocorticotropin receptor binding|adrenocorticotropic hormone receptor ligand|corticotropin receptor binding										GO:0071856			molecular_function											owl:Class	
GO:0001096	biolink:NamedThing	TFIIF-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	got7fsn_ti	TFIIF-class transcription factor binding						krc	2010-10-28T02:51:20Z						molecular_function											owl:Class	
GO:0001091	biolink:NamedThing	RNA polymerase II general transcription initiation factor binding	Binding to a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.	got7fsn_ti	RNA polymerase II basal transcription factor binding						krc	2010-10-28T02:30:02Z						molecular_function											owl:Class	
GO:0001164	biolink:NamedThing	RNA polymerase I core promoter sequence-specific DNA binding	Binding to a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE.	got7fsn_ti	RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity|transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting|RNA polymerase I core promoter sequence-specific DNA binding|RNA polymerase I core element sequence-specific DNA binding|RNA polymerase I CORE element sequence-specific DNA binding						krc	2011-01-31T04:47:48Z			GO:0001187			molecular_function											owl:Class	
GO:0001046	biolink:NamedThing	core promoter sequence-specific DNA binding	Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.	got7fsn_ti	core promoter binding	https://github.com/geneontology/go-ontology/issues/19312					krc	2010-08-25T04:17:44Z			GO:0001047			molecular_function											owl:Class	
GO:0070686	biolink:NamedThing	macropinocytic cup membrane	The portion of the plasma membrane surrounding a macropinocytic cup.	got7fsn_ti	crown membrane						mah	2009-06-03T10:52:25Z						cellular_component											owl:Class	
GO:0031253	biolink:NamedThing	cell projection membrane	The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.	got7fsn_ti	membrane projection|membrane extension													cellular_component											owl:Class	
GO:0005582	biolink:NamedThing	collagen type XV trimer	A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0034778	biolink:NamedThing	2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1003		molecular_function											owl:Class	
GO:0097254	biolink:NamedThing	renal tubular secretion	Secretion of substances from peritubular capillaries into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.	got7fsn_ti							pr	2012-03-05T02:03:58Z						biological_process											owl:Class	
GO:0033430	biolink:NamedThing	CGC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CGC codon.	got7fsn_ti	arginine tRNA				Note that in the standard genetic code, CGC codes for arginine.									molecular_function											owl:Class	
GO:0021703	biolink:NamedThing	locus ceruleus development	The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.	got7fsn_ti	locus caeruleus development|locus coeruleus development													biological_process											owl:Class	
GO:0050018	biolink:NamedThing	L-amino-acid dehydrogenase activity	Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH.	got7fsn_ti	L-amino-acid:NAD+ oxidoreductase (deaminating)											MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN|RHEA:10396|EC:1.4.1.5		molecular_function											owl:Class	
GO:0016639	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.	got7fsn_ti												EC:1.4.1.-		molecular_function											owl:Class	
GO:0034830	biolink:NamedThing	(2Z)-2,4-dihydroxydec-2-enedioate aldolase activity	Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate.	got7fsn_ti												UM-BBD_reactionID:r1174|EC:4.1.3.-		molecular_function											owl:Class	
GO:0097380	biolink:NamedThing	dorsal spinal cord interneuron anterior axon guidance	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	got7fsn_ti	dorsal interneuron rostral axon projection						pr	2012-10-01T10:24:41Z						biological_process											owl:Class	
GO:0034430	biolink:NamedThing	monolayer-surrounded lipid storage body outer lipid monolayer	The single layer of phopholipids surrounding a lipid storage body.	got7fsn_ti	spherosome outer lipid monolayer|oleosome outer lipid monolayer|lipid storage body surface lipid monolayer|lipid droplet outer lipid monolayer|oil body outer lipid monolayer													cellular_component											owl:Class	
GO:0034646	biolink:NamedThing	organelle-enclosing lipid monolayer	A lipid monolayer that surrounds and encloses an organelle.	got7fsn_ti														cellular_component											owl:Class	
GO:0004619	biolink:NamedThing	phosphoglycerate mutase activity	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate.	got7fsn_ti	diphosphoglycomutase|GriP mutase|phosphoglyceromutase activity|bisphosphoglyceromutase|D-phosphoglycerate 2,3-phosphomutase activity|PGM|monophosphoglyceromutase activity|PGA mutase activity|PGAM activity|phosphoglycerate phosphomutase activity|MPGM|monophosphoglycerate mutase activity											RHEA:15901|MetaCyc:3PGAREARR-RXN|Reactome:R-HSA-71654|EC:5.4.2.1|Reactome:R-HSA-71445		molecular_function											owl:Class	
GO:0031696	biolink:NamedThing	alpha-2C adrenergic receptor binding	Binding to an alpha-2C adrenergic receptor.	got7fsn_ti	alpha-2C adrenergic receptor ligand													molecular_function											owl:Class	
GO:0006165	biolink:NamedThing	nucleoside diphosphate phosphorylation	The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0046939	biolink:NamedThing	nucleotide phosphorylation	The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside.	got7fsn_ti														biological_process											owl:Class	
GO:0060921	biolink:NamedThing	sinoatrial node cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.	got7fsn_ti	sinus node cell differentiation|SAN cell differentiation|SA node cell differentiation						dph	2009-09-29T11:03:30Z						biological_process											owl:Class	
GO:0045684	biolink:NamedThing	positive regulation of epidermis development	Any process that activates or increases the frequency, rate or extent of epidermis development.	got7fsn_ti	positive regulation of hypodermis development|positive regulation of epidermal development|stimulation of epidermis development|up regulation of epidermis development|upregulation of epidermis development|up-regulation of epidermis development|activation of epidermis development													biological_process											owl:Class	
GO:0046809	biolink:NamedThing	replication compartment	Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously.	got7fsn_ti	RC													cellular_component											owl:Class	
GO:0039715	biolink:NamedThing	nuclear viral factory	A viral factory located in the nucleus of a host cell.	got7fsn_ti							bf	2013-12-19T15:18:07Z						cellular_component											owl:Class	
GO:0050365	biolink:NamedThing	tryptophanamidase activity	Catalysis of the reaction: L-tryptophanamide + H(2)O = L-tryptophan + NH(4)(+).	got7fsn_ti	L-tryptophanamide amidohydrolase activity|tryptophan aminopeptidase|L-tryptophan aminopeptidase											MetaCyc:TRYPTOPHANAMIDASE-RXN|KEGG_REACTION:R00682|EC:3.5.1.57|RHEA:11012		molecular_function											owl:Class	
GO:0032535	biolink:NamedThing	regulation of cellular component size	A process that modulates the size of a cellular component.	got7fsn_ti														biological_process											owl:Class	
GO:0090066	biolink:NamedThing	regulation of anatomical structure size	Any process that modulates the size of an anatomical structure.	got7fsn_ti							tb	2009-09-02T11:00:08Z						biological_process											owl:Class	
GO:0010444	biolink:NamedThing	guard mother cell differentiation	The process in which a meristemoid acquires the specialized features of a guard mother cell.	got7fsn_ti														biological_process											owl:Class	
GO:0035234	biolink:NamedThing	ectopic germ cell programmed cell death	Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.	got7fsn_ti	programmed cell death, ectopic germ cells|programmed cell death of ectopic germ cells													biological_process											owl:Class	
GO:0043102	biolink:NamedThing	amino acid salvage	Any process which produces an amino acid from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0008652	biolink:NamedThing	cellular amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.	got7fsn_ti	amino acid biosynthetic process|cellular amino acid biosynthesis|cellular amino acid formation|cellular amino acid anabolism|cellular amino acid synthesis											Wikipedia:Amino_acid_synthesis		biological_process											owl:Class	
GO:0102981	biolink:NamedThing	4-hydroxy-5-methyl-2-propyl-3(2H)-furanone oxidoreductase activity	Catalysis of the reaction: 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NADP <=> (2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-9567		molecular_function											owl:Class	
GO:0006867	biolink:NamedThing	asparagine transport	The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-asparagine transport													biological_process											owl:Class	
GO:0015804	biolink:NamedThing	neutral amino acid transport	The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0032093	biolink:NamedThing	SAM domain binding	Binding to a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.	got7fsn_ti	Sterile Alpha Motif domain binding													molecular_function											owl:Class	
GO:0031219	biolink:NamedThing	levanase activity	Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units.	got7fsn_ti	2,6-beta-D-fructan fructanohydrolase activity|levan hydrolase activity											EC:3.2.1.65|MetaCyc:3.2.1.65-RXN		molecular_function											owl:Class	
GO:2000857	biolink:NamedThing	positive regulation of mineralocorticoid secretion	Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion.	got7fsn_ti							bf	2011-07-26T08:46:45Z						biological_process											owl:Class	
GO:2000855	biolink:NamedThing	regulation of mineralocorticoid secretion	Any process that modulates the frequency, rate or extent of mineralocorticoid secretion.	got7fsn_ti							bf	2011-07-26T08:46:38Z						biological_process											owl:Class	
GO:0038055	biolink:NamedThing	BMP secretion	The controlled release of a member of the BMP family of proteins from a cell.	got7fsn_ti	BMP protein secretion|bone morphogenetic protein secretion						bf	2011-12-14T02:31:39Z						biological_process											owl:Class	
GO:0102603	biolink:NamedThing	12-demethyl-elloramycin C12a O-methyltransferase activity	Catalysis of the reaction: 12-demethyl-elloramycin + S-adenosyl-L-methionine  <=> elloramycin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-15402		molecular_function											owl:Class	
GO:0071039	biolink:NamedThing	nuclear polyadenylation-dependent CUT catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.	got7fsn_ti	nuclear poly(A)-dependent CUT catabolic process						krc	2009-07-29T01:10:34Z						biological_process											owl:Class	
GO:0071034	biolink:NamedThing	CUT catabolic process	The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).	got7fsn_ti	cryptic unstable transcript catabolic process						krc	2009-07-29T12:38:04Z						biological_process											owl:Class	
GO:0007565	biolink:NamedThing	female pregnancy	The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.	got7fsn_ti	carrying of young|gestation											Wikipedia:Gestation		biological_process											owl:Class	
GO:0044706	biolink:NamedThing	multi-multicellular organism process	A multicellular organism process which involves another multicellular organism of the same or different species.	got7fsn_ti							jl	2012-09-19T16:06:16Z						biological_process											owl:Class	
GO:0032259	biolink:NamedThing	methylation	The process in which a methyl group is covalently attached to a molecule.	got7fsn_ti												Wikipedia:Methylation		biological_process											owl:Class	
GO:0046436	biolink:NamedThing	D-alanine metabolic process	The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid.	got7fsn_ti	D-alanine metabolism													biological_process											owl:Class	
GO:0046144	biolink:NamedThing	D-alanine family amino acid metabolic process	The chemical reactions and pathways involving D-alanine and related amino acids.	got7fsn_ti	D-alanine family amino acid metabolism													biological_process											owl:Class	
GO:0050056	biolink:NamedThing	linalool 8-monooxygenase activity	Catalysis of the reaction: AH(2) + linalool + O(2) = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H(2)O.	got7fsn_ti	3,7-dimethylocta-1,6-dien-3-ol,hydrogen-donor:oxygen oxidoreductase (8-hydroxylating)											EC:1.14.99.28|MetaCyc:LINALOOL-8-MONOOXYGENASE-RXN|RHEA:20760|KEGG_REACTION:R04366		molecular_function											owl:Class	
GO:0061342	biolink:NamedThing	regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway	Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart.	got7fsn_ti	regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signalling pathway						dph	2010-09-29T11:30:15Z						biological_process											owl:Class	
GO:0022413	biolink:NamedThing	reproductive process in single-celled organism	A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism.	got7fsn_ti														biological_process											owl:Class	
GO:0060949	biolink:NamedThing	cardiac vascular smooth muscle cell fate commitment	The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.	got7fsn_ti	heart vascular smooth muscle cell fate commitment						dph	2009-09-29T03:02:45Z						biological_process											owl:Class	
GO:0060911	biolink:NamedThing	cardiac cell fate commitment	The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system.	got7fsn_ti	cardiocyte cell fate commitment						dph	2009-09-17T08:47:00Z						biological_process											owl:Class	
GO:0019008	biolink:NamedThing	molybdopterin synthase complex	A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.	got7fsn_ti	molybdopterin converting factor complex										GO:0019009			cellular_component											owl:Class	
GO:0030931	biolink:NamedThing	heterotetrameric ADPG pyrophosphorylase complex	A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity. An example of this process is found in Mus musculus.	got7fsn_ti														cellular_component											owl:Class	
GO:0030929	biolink:NamedThing	ADPG pyrophosphorylase complex	Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits.	got7fsn_ti														cellular_component											owl:Class	
GO:0014032	biolink:NamedThing	neural crest cell development	The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0014031	biolink:NamedThing	mesenchymal cell development	The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0018009	biolink:NamedThing	N-terminal peptidyl-L-cysteine N-palmitoylation	The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.	got7fsn_ti												RESID:AA0060		biological_process											owl:Class	
GO:0006500	biolink:NamedThing	N-terminal protein palmitoylation	The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0044620	biolink:NamedThing	ACP phosphopantetheine attachment site binding	Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).	got7fsn_ti							jl	2012-07-04T03:25:04Z						molecular_function											owl:Class	
GO:0051192	biolink:NamedThing	prosthetic group binding	Binding to a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0071342	biolink:NamedThing	regulation of establishment of actomyosin contractile ring localization	Any process that modulates the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location that contributes to cytokinesis during cell cycle.	got7fsn_ti	regulation of establishment of contractile ring localization involved in cell cycle cytokinesis|regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle|regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis						mah	2009-12-11T01:22:11Z						biological_process											owl:Class	
GO:0044087	biolink:NamedThing	regulation of cellular component biogenesis	Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.	got7fsn_ti														biological_process											owl:Class	
GO:0102946	biolink:NamedThing	soyasapogenol E UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + soyasapogenol E <=> UDP + a soyasapogenol E monoglucoside.	got7fsn_ti												MetaCyc:RXN-9038		molecular_function											owl:Class	
GO:0044058	biolink:NamedThing	regulation of digestive system process	Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0002939	biolink:NamedThing	tRNA N1-guanine methylation	The process whereby a guanine in tRNA is methylated at position N1 of the guanine.	got7fsn_ti	tRNA m1-guanine biosynthesis						hjd	2012-11-09T16:18:41Z						biological_process											owl:Class	
GO:0060471	biolink:NamedThing	cortical granule exocytosis	The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.	got7fsn_ti	cortical reaction|cortical granule release	https://github.com/geneontology/go-ontology/issues/13980												biological_process											owl:Class	
GO:0017156	biolink:NamedThing	calcium-ion regulated exocytosis	The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.	got7fsn_ti	calcium ion-dependent exocytosis				Note that the calcium regulated exocytosis pathway can be leaky: some level of exocytosis via this pathway occurs spontaneously.  This phenomenon underlies spontaneous neurotransmitter release from presynapses.  This phenomenon is distinct from the unregulated, calcium independent exocytosis pathway.									biological_process											owl:Class	
GO:0000743	biolink:NamedThing	nuclear migration involved in conjugation with cellular fusion	The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion.	got7fsn_ti	nuclear congression|nuclear migration during conjugation with cellular fusion										GO:0006946			biological_process											owl:Class	
GO:0030473	biolink:NamedThing	nuclear migration along microtubule	The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.	got7fsn_ti	nuclear movement, microtubule-mediated|transport of nucleus, microtubule-mediated|microtubule cytoskeleton-dependent nucleus positioning|microtubule-dependent nuclear positioning|transport of nucleus by microtubules|microtubule cytoskeleton-dependent nuclear positioning|nucleus migration|microtubule-dependent nucleus positioning|nuclear migration, microtubule-mediated|microtubule-mediated nuclear migration										GO:0000065			biological_process											owl:Class	
GO:0008096	biolink:NamedThing	juvenile hormone epoxide hydrolase activity	Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol.	got7fsn_ti												EC:3.3.2.-		molecular_function											owl:Class	
GO:0004301	biolink:NamedThing	epoxide hydrolase activity	Catalysis of the reaction: an epoxide + H2O = a glycol.	got7fsn_ti	aryl epoxide hydrase activity|sEH|trans-stilbene oxide hydrolase activity|epoxide hydrase activity|soluble epoxide hydrolase activity|epoxide hydratase activity|cytosolic epoxide hydrolase activity|arene-oxide hydratase activity											Reactome:R-HSA-9020257|RHEA:19037|Reactome:R-HSA-9018862|Reactome:R-HSA-9024973|Reactome:R-HSA-9020270|EC:3.3.2.10|Reactome:R-HSA-9020258|Reactome:R-HSA-9026008|MetaCyc:3.3.2.10-RXN|Reactome:R-HSA-9026000|Reactome:R-HSA-9020252|Reactome:R-HSA-9020253|UM-BBD_enzymeID:e0397|Reactome:R-HSA-9025998|Reactome:R-HSA-9018877|Reactome:R-HSA-9024993|Reactome:R-HSA-9024890|Reactome:R-HSA-2161961		molecular_function											owl:Class	
GO:0001550	biolink:NamedThing	ovarian cumulus expansion	Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.	got7fsn_ti	ovarian cumulus growth													biological_process											owl:Class	
GO:0006783	biolink:NamedThing	heme biosynthetic process	The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.	got7fsn_ti	heme biosynthesis|heme formation|haem biosynthesis|heme synthesis|haem biosynthetic process|heme anabolism											MetaCyc:HEMESYN2-PWY		biological_process											owl:Class	
GO:0060343	biolink:NamedThing	trabecula formation	The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.	got7fsn_ti	trabecula biogenesis|trabeculation													biological_process											owl:Class	
GO:0017099	biolink:NamedThing	very-long-chain-acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	got7fsn_ti	very long-chain-acyl-CoA dehydrogenase activity											Reactome:R-HSA-548831		molecular_function											owl:Class	
GO:0004466	biolink:NamedThing	long-chain-acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF.	got7fsn_ti	palmitoyl-coenzyme A dehydrogenase activity|palmitoyl-CoA dehydrogenase activity|long-chain-acyl-CoA:acceptor 2,3-oxidoreductase activity|long-chain acyl-coenzyme A dehydrogenase activity|long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase activity											EC:1.3.8.8|RHEA:17721|MetaCyc:LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0048200	biolink:NamedThing	Golgi transport vesicle coating	The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles.	got7fsn_ti	dictyosome transport vesicle coating													biological_process											owl:Class	
GO:0006901	biolink:NamedThing	vesicle coating	A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination.	got7fsn_ti	vesicle coat assembly													biological_process											owl:Class	
GO:1990907	biolink:NamedThing	beta-catenin-TCF complex	A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.	got7fsn_ti	beta-catenin/LEF complex|beta-catenin/T-cell factor complex|beta-catenin/lymphoid enhancer binding factor complex						bf	2015-12-01T16:32:44Z						cellular_component											owl:Class	
GO:0090575	biolink:NamedThing	RNA polymerase II transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.	got7fsn_ti	RNA polymerase II transcription factor complex						tb	2014-05-09T14:04:37Z						cellular_component											owl:Class	
GO:0030054	biolink:NamedThing	cell junction	A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.	got7fsn_ti												Wikipedia:Cell_junction		cellular_component											owl:Class	
GO:0021791	biolink:NamedThing	chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti	positive chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme													biological_process											owl:Class	
GO:0021789	biolink:NamedThing	branchiomotor neuron axon guidance in branchial arch mesenchyme	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti														biological_process											owl:Class	
GO:0097021	biolink:NamedThing	lymphocyte migration into lymphoid organs	The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.	got7fsn_ti	lymphocyte homing						pr	2011-03-29T04:26:08Z						biological_process											owl:Class	
GO:0072676	biolink:NamedThing	lymphocyte migration	The movement of a lymphocyte within or between different tissues and organs of the body.	got7fsn_ti							mah	2011-02-22T03:38:12Z						biological_process											owl:Class	
GO:0019728	biolink:NamedThing	peptidyl-allysine oxidation to 2-aminoadipic acid	The oxidation of allysine to 2-aminoadipic acid.	got7fsn_ti												RESID:AA0370		biological_process											owl:Class	
GO:0018158	biolink:NamedThing	protein oxidation	The modification of a protein amino acid by oxidation.	got7fsn_ti	protein amino acid oxidation													biological_process											owl:Class	
GO:0031978	biolink:NamedThing	plastid thylakoid lumen	The volume enclosed by a plastid thylakoid membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0031977	biolink:NamedThing	thylakoid lumen	The volume enclosed by a thylakoid membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0031785	biolink:NamedThing	type 1A melatonin receptor binding	Binding to a type 1A melatonin receptor.	got7fsn_ti	type 1A melatonin receptor ligand													molecular_function											owl:Class	
GO:0031784	biolink:NamedThing	melatonin receptor binding	Binding to a melatonin receptor.	got7fsn_ti	melatonin receptor ligand													molecular_function											owl:Class	
GO:0033819	biolink:NamedThing	lipoyl(octanoyl) transferase activity	Catalysis of the reaction: octanoyl-[acyl-carrier protein] + protein = protein N6-(octanoyl)lysine + acyl-carrier protein.	got7fsn_ti	octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity|lipoyl (octanoyl)-acyl carrier protein:protein transferase activity|lipoate/octanoate transferase activity|LipB|octanoyl-acyl carrier protein-protein N-octanoyltransferase activity|lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity|octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity											Reactome:R-HSA-6793590|MetaCyc:RXN0-947|EC:2.3.1.181		molecular_function											owl:Class	
GO:0070762	biolink:NamedThing	nuclear pore transmembrane ring	A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.	got7fsn_ti	NDC1 subcomplex|NDC1 complex						mah	2009-06-29T11:02:56Z						cellular_component											owl:Class	
GO:0098843	biolink:NamedThing	postsynaptic endocytic zone	A stably positioned site of clathrin adjacent and physically attached to the postsynaptic specialization, which is the site of endocytosis of post-synaptic proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0061163	biolink:NamedThing	endoplasmic reticulum polarization	The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.	got7fsn_ti	establishment of endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site|ER polarization|establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site|endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site|ER localization involved in ER polarization at cell division site|endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site|transitional endoplasmic reticulum polarization at cell division site|maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site	https://github.com/geneontology/go-ontology/issues/20666					dph	2010-06-25T09:51:48Z			GO:0061166|GO:0061165|GO:0061164|GO:0061167			biological_process											owl:Class	
GO:0007029	biolink:NamedThing	endoplasmic reticulum organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.	got7fsn_ti	ER organisation|endoplasmic reticulum morphology|ER organization and biogenesis|endoplasmic reticulum organization and biogenesis|endoplasmic reticulum organisation													biological_process											owl:Class	
GO:0060220	biolink:NamedThing	camera-type eye photoreceptor cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye.	got7fsn_ti														biological_process											owl:Class	
GO:0042706	biolink:NamedThing	eye photoreceptor cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.	got7fsn_ti														biological_process											owl:Class	
GO:0097167	biolink:NamedThing	circadian regulation of translation	Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours.	got7fsn_ti	regulation of mRNA translation in response to circadian clock						pr	2011-09-29T03:13:31Z						biological_process											owl:Class	
GO:0007623	biolink:NamedThing	circadian rhythm	Any biological process in an organism that recurs with a regularity of approximately 24 hours.	got7fsn_ti	circadian response|circadian process|response to circadian rhythm										GO:0050895	Wikipedia:Circadian_rhythm		biological_process											owl:Class	
GO:0030742	biolink:NamedThing	GTP-dependent protein binding	Binding to a protein or protein complex when at least one of the interacting partners is in the GTP-bound state.	got7fsn_ti					This term may be used to annotate both partners in a GTP-dependent binding interaction, both the GTP-bound protein and the protein(s) which interact with it.									molecular_function											owl:Class	
GO:0061791	biolink:NamedThing	GTPase motor activity	A motor activity driven by GTP hydrolysis.	got7fsn_ti							dph	2016-09-09T13:17:29Z						molecular_function											owl:Class	
GO:0003924	biolink:NamedThing	GTPase activity	Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	heterotrimeric G-protein GTPase, beta-subunit|hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement|tubulin GTPase activity|heterotrimeric G-protein GTPase, gamma-subunit|protein-synthesizing GTPase activity, initiation|Rho small monomeric GTPase activity|protein-synthesizing GTPase activity, termination|heterotrimeric G-protein GTPase, alpha-subunit|signal-recognition-particle GTPase activity|heterotrimeric G-protein GTPase activity|Ran small monomeric GTPase activity|small monomeric GTPase activity|Sar small monomeric GTPase activity|protein-synthesizing GTPase activity, elongation|RHEB small monomeric GTPase activity|Ras small monomeric GTPase activity|Rab small monomeric GTPase activity|ARF small monomeric GTPase activity|GTPase activity, coupled|dynamin GTPase activity|protein-synthesizing GTPase activity	https://github.com/geneontology/go-ontology/issues/19078					dph	2015-11-11T12:47:56Z			GO:0061745	Reactome:R-HSA-5658231|Reactome:R-HSA-5623513|Reactome:R-HSA-380979|Reactome:R-HSA-5694527|Reactome:R-HSA-2130641|Reactome:R-HSA-156923|Reactome:R-HSA-8982025|Reactome:R-HSA-170686|Reactome:R-HSA-164381|Reactome:R-HSA-983422|Reactome:R-HSA-6814833|Reactome:R-HSA-9649736|Reactome:R-HSA-5389842|Reactome:R-HSA-392212|Reactome:R-HSA-421835|Reactome:R-HSA-8854255|Reactome:R-HSA-8868661|Reactome:R-HSA-177501|Reactome:R-HSA-5419279|Reactome:R-HSA-555065|Reactome:R-HSA-8847534|Reactome:R-HSA-9640195|Reactome:R-HSA-428941|Reactome:R-HSA-167415|Reactome:R-HSA-6807877|Reactome:R-HSA-5419273|Reactome:R-HSA-8854604|Reactome:R-HSA-5665809|Reactome:R-HSA-8854329|Reactome:R-HSA-8854173|Reactome:R-HSA-8849082|Reactome:R-HSA-1445143|Reactome:R-HSA-418574|Reactome:R-HSA-5389839|Reactome:R-HSA-2130725|Reactome:R-HSA-5638006|Reactome:R-HSA-432707|Reactome:R-HSA-8854612|Reactome:R-HSA-1458485|Reactome:R-HSA-5333615|Reactome:R-HSA-9645598|Reactome:R-HSA-418582|Reactome:R-HSA-5672017|Reactome:R-HSA-8982021|Reactome:R-HSA-165055|Reactome:R-HSA-2584246|Reactome:R-HSA-170666|Reactome:R-HSA-8981353|Reactome:R-HSA-8982020|Reactome:R-HSA-8847883|Reactome:R-HSA-392133|Reactome:R-HSA-203973|RHEA:19669|Reactome:R-HSA-170685		molecular_function											owl:Class	
GO:0075135	biolink:NamedThing	suppression by symbiont of host calcium or calmodulin-mediated signal transduction	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction|negative regulation by symbiont of host calcium or calmodulin-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "Negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075105".									biological_process											owl:Class	
GO:0075133	biolink:NamedThing	modulation by symbiont of host calcium or calmodulin-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host Ca++ or calmodulin-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075103".									biological_process											owl:Class	
GO:1900613	biolink:NamedThing	F-9775B catabolic process	The chemical reactions and pathways resulting in the breakdown of F-9775B.	got7fsn_ti	F-9775B breakdown|F-9775B degradation|F-9775B catabolism						di	2012-05-15T07:03:24Z						biological_process											owl:Class	
GO:0090487	biolink:NamedThing	secondary metabolite catabolic process	The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.	got7fsn_ti	secondary metabolite degradation|secondary metabolite breakdown|secondary metabolite catabolism						tb	2012-10-15T16:43:09Z						biological_process											owl:Class	
GO:1904364	biolink:NamedThing	positive regulation of calcitonin secretion	Any process that activates or increases the frequency, rate or extent of calcitonin secretion.	got7fsn_ti	up-regulation of calcitonin secretion|up regulation of calcitonin secretion|upregulation of calcitonin secretion|activation of calcitonin secretion						sl	2015-06-15T17:55:05Z						biological_process											owl:Class	
GO:0004078	biolink:NamedThing	biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)).	got7fsn_ti	biotin:apo-3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|beta-methylcrotonyl coenzyme A holocarboxylase synthetase activity|biotin-methylcrotonoyl-CoA-carboxylase synthetase|biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase activity|biotin--[methylcrotonoyl-CoA-carboxylase] synthetase activity|biotin-methylcrotonoyl-CoA-carboxylase ligase activity											MetaCyc:6.3.4.11-RXN|RHEA:24376|EC:6.3.4.11		molecular_function											owl:Class	
GO:0018271	biolink:NamedThing	biotin-protein ligase activity	Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein.	got7fsn_ti	biotin-apoprotein ligase activity										GO:0000106	MetaCyc:BIOTINLIG-RXN|Reactome:R-HSA-9035987|Reactome:R-HSA-2993447|Reactome:R-HSA-9035990|Reactome:R-HSA-3323184|Reactome:R-HSA-9035988|Reactome:R-HSA-2993802|Reactome:R-HSA-2993799|EC:6.3.4.-|Reactome:R-HSA-4167511|Reactome:R-HSA-2993814		molecular_function											owl:Class	
GO:0043025	biolink:NamedThing	neuronal cell body	The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.	got7fsn_ti	neuron cell body|neuronal cell soma				Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.							NIF_Subcellular:sao1044911821|Wikipedia:Soma_(biology)		cellular_component											owl:Class	
GO:0044297	biolink:NamedThing	cell body	The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.	got7fsn_ti	cell soma				Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.		jl	2010-02-05T10:37:16Z				FBbt:00005107|FMA:67301|Wikipedia:Cell_body		cellular_component											owl:Class	
GO:1900572	biolink:NamedThing	diorcinol biosynthetic process	The chemical reactions and pathways resulting in the formation of diorcinol.	got7fsn_ti	diorcinol biosynthesis|diorcinol anabolism|diorcinol formation|diorcinol synthesis						di	2012-05-15T06:35:29Z						biological_process											owl:Class	
GO:0001854	biolink:NamedThing	complement component C3d binding	Binding to a C3d product of the complement cascade.	got7fsn_ti														molecular_function											owl:Class	
GO:0001848	biolink:NamedThing	complement binding	Binding to a component or product of the complement cascade.	got7fsn_ti					Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways.									molecular_function											owl:Class	
GO:0007394	biolink:NamedThing	dorsal closure, elongation of leading edge cells	The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis.	got7fsn_ti														biological_process											owl:Class	
GO:0034249	biolink:NamedThing	negative regulation of cellular amide metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.	got7fsn_ti	negative regulation of amide metabolism													biological_process											owl:Class	
GO:0034248	biolink:NamedThing	regulation of cellular amide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.	got7fsn_ti	regulation of amide metabolism													biological_process											owl:Class	
GO:0010233	biolink:NamedThing	phloem transport	The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0010232	biolink:NamedThing	vascular transport	The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0005813	biolink:NamedThing	centrosome	A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.	got7fsn_ti												Wikipedia:Centrosome		cellular_component											owl:Class	
GO:0005815	biolink:NamedThing	microtubule organizing center	An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.	got7fsn_ti	MTOC|microtubule organising centre											Wikipedia:Microtubule_organizing_center		cellular_component											owl:Class	
GO:0061664	biolink:NamedThing	Pup ligase activity	Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S --> X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3						dph	2014-11-06T13:59:09Z						molecular_function											owl:Class	
GO:0006119	biolink:NamedThing	oxidative phosphorylation	The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.	got7fsn_ti	respiratory-chain phosphorylation											Wikipedia:Oxidative_phosphorylation		biological_process											owl:Class	
GO:0006091	biolink:NamedThing	generation of precursor metabolites and energy	The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.	got7fsn_ti	metabolic energy generation|intermediary metabolism|energy pathways													biological_process											owl:Class	
GO:0001667	biolink:NamedThing	ameboidal-type cell migration	Cell migration that is accomplished by extension and retraction of a pseudopodium.	got7fsn_ti	amoeboid cell migration|amoeboidal cell migration|ameboid cell migration				Note that this term refers to a mode of migration rather than to any particular cell type.									biological_process											owl:Class	
GO:0016477	biolink:NamedThing	cell migration	The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.	got7fsn_ti												Wikipedia:Cell_migration		biological_process											owl:Class	
GO:0019697	biolink:NamedThing	L-xylitol catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.	got7fsn_ti	L-xylitol utilization|L-xylitol degradation to xylulose 5-phosphate|L-xylitol breakdown to xylulose 5-phosphate|L-arabitol and xylitol degradation											MetaCyc:LARABITOLUTIL-PWY		biological_process											owl:Class	
GO:1901159	biolink:NamedThing	xylulose 5-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate.	got7fsn_ti	xylulose 5-phosphate formation|xylulose 5-phosphate biosynthesis|xylulose 5-phosphate synthesis|xylulose 5-phosphate anabolism						bf	2012-07-18T04:42:24Z						biological_process											owl:Class	
GO:0048654	biolink:NamedThing	anther morphogenesis	The process in which the anatomical structures of the anther are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0004549	biolink:NamedThing	tRNA-specific ribonuclease activity	Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.	got7fsn_ti	tRNA-specific RNase activity											Reactome:R-HSA-5696815|Reactome:R-HSA-6786854|Reactome:R-HSA-6785722|Reactome:R-HSA-5696813		molecular_function											owl:Class	
GO:0061482	biolink:NamedThing	response to irinotecan	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus.	got7fsn_ti							dph	2012-11-07T09:15:03Z						biological_process											owl:Class	
GO:0071252	biolink:NamedThing	cellular response to sulfur dioxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.	got7fsn_ti							mah	2009-12-03T03:10:16Z						biological_process											owl:Class	
GO:0019676	biolink:NamedThing	ammonia assimilation cycle	The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.	got7fsn_ti	glutamate metabolism via glutamine and ammonia|glutamate metabolic process via glutamine and ammonia											MetaCyc:PWY-3282|MetaCyc:AMMASSIM-PWY		biological_process											owl:Class	
GO:0019740	biolink:NamedThing	nitrogen utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:1990748	biolink:NamedThing	cellular detoxification	Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.	got7fsn_ti							vw	2015-05-18T16:17:46Z						biological_process											owl:Class	
GO:0035595	biolink:NamedThing	N-acetylglucosaminylinositol deacetylase activity	Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol.	got7fsn_ti	1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase activity|GlcNAc-Ins deacetylase activity|1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase activity|N-acetyl-1D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase activity						bf	2010-11-11T02:12:48Z				EC:3.5.1.103|KEGG_REACTION:R09651|RHEA:26180|MetaCyc:RXN1G-2		molecular_function											owl:Class	
GO:0000152	biolink:NamedThing	nuclear ubiquitin ligase complex	A ubiquitin ligase complex found in the nucleus.	got7fsn_ti														cellular_component											owl:Class	
GO:0060389	biolink:NamedThing	pathway-restricted SMAD protein phosphorylation	The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.	got7fsn_ti	R-SMAD protein phosphorylation|pathway restricted SMAD protein phosphorylation|receptor regulated SMAD protein phosphorylation|receptor-regulated SMAD protein phosphorylation													biological_process											owl:Class	
GO:0006468	biolink:NamedThing	protein phosphorylation	The process of introducing a phosphate group on to a protein.	got7fsn_ti	protein amino acid phosphorylation													biological_process											owl:Class	
GO:0047182	biolink:NamedThing	alcohol O-cinnamoyltransferase activity	Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate.	got7fsn_ti	1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase activity											MetaCyc:2.3.1.152-RXN|EC:2.3.1.152|RHEA:23524		molecular_function											owl:Class	
GO:0048601	biolink:NamedThing	oocyte morphogenesis	The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte.	got7fsn_ti	oocyte morphogenesis during differentiation													biological_process											owl:Class	
GO:0034875	biolink:NamedThing	caffeine oxidase activity	Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O.	got7fsn_ti												EC:1.17.5.2|RHEA:47148|UM-BBD_reactionID:r1321		molecular_function											owl:Class	
GO:0033695	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule.	got7fsn_ti												EC:1.17.5.-		molecular_function											owl:Class	
GO:0008317	biolink:NamedThing	gurken receptor binding	Binding to a gurken growth factor receptor.	got7fsn_ti	gurken receptor ligand													molecular_function											owl:Class	
GO:0005154	biolink:NamedThing	epidermal growth factor receptor binding	Binding to an epidermal growth factor receptor.	got7fsn_ti	transforming growth factor alpha receptor binding|transforming growth factor alpha receptor ligand|EGF receptor ligand|EGF|epidermal growth factor receptor ligand|epidermal growth factor|TGF-alpha receptor binding|EGFR binding|transforming growth factor alpha|TGFalpha receptor binding|EGF receptor binding										GO:0008185			molecular_function											owl:Class	
GO:0005542	biolink:NamedThing	folic acid binding	Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.	got7fsn_ti	vitamin B9 binding|vitamin M binding|folate binding													molecular_function											owl:Class	
GO:0010441	biolink:NamedThing	guard cell development	The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0031812	biolink:NamedThing	P2Y1 nucleotide receptor binding	Binding to a P2Y1 nucleotide receptor.	got7fsn_ti	P2Y1 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0031811	biolink:NamedThing	G protein-coupled nucleotide receptor binding	Binding to a G protein-coupled (metabotropic) nucleotide receptor.	got7fsn_ti	G-protein coupled nucleotide receptor binding|metabotropic nucleotide receptor binding|P2Y receptor binding|metabotropic nucleotide receptor ligand													molecular_function											owl:Class	
GO:0046239	biolink:NamedThing	phthalate catabolic process	The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid.	got7fsn_ti	phthalate degradation|phthalate breakdown|phthalate catabolism													biological_process											owl:Class	
GO:0040013	biolink:NamedThing	negative regulation of locomotion	Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.	got7fsn_ti	down-regulation of locomotion|down regulation of locomotion|downregulation of locomotion|inhibition of locomotion													biological_process											owl:Class	
GO:0048519	biolink:NamedThing	negative regulation of biological process	Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.	got7fsn_ti	down regulation of biological process|downregulation of biological process|inhibition of biological process|negative regulation of physiological process|down-regulation of biological process										GO:0043118			biological_process											owl:Class	
GO:1904251	biolink:NamedThing	regulation of bile acid metabolic process	Any process that modulates the frequency, rate or extent of bile acid metabolic process.	got7fsn_ti	regulation of bile acid metabolism						bf	2015-05-20T11:04:28Z						biological_process											owl:Class	
GO:0003106	biolink:NamedThing	negative regulation of glomerular filtration by angiotensin	The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.	got7fsn_ti	regulation of glomerular filtration by angiotensin|angiotensin-mediated regulation of glomerular filtration													biological_process											owl:Class	
GO:0003083	biolink:NamedThing	negative regulation of renal output by angiotensin	The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney.	got7fsn_ti	angiotensin mediated negative regulation of renal output|angiotensin-mediated negative regulation of renal output													biological_process											owl:Class	
GO:0005778	biolink:NamedThing	peroxisomal membrane	The lipid bilayer surrounding a peroxisome.	got7fsn_ti	peroxisome membrane													cellular_component											owl:Class	
GO:0031903	biolink:NamedThing	microbody membrane	The lipid bilayer surrounding a microbody.	got7fsn_ti														cellular_component											owl:Class	
GO:0006730	biolink:NamedThing	one-carbon metabolic process	The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.	got7fsn_ti	one carbon metabolic process|one-carbon transfer metabolism|one-carbon transfer metabolic process|one-carbon metabolism|one carbon metabolism										GO:0019753|GO:0019754	UM-BBD_pathwayID:C1cyc		biological_process											owl:Class	
GO:0044281	biolink:NamedThing	small molecule metabolic process	The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.	got7fsn_ti	small molecule metabolism				Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.		jl	2010-01-26T12:05:20Z						biological_process											owl:Class	
GO:0046012	biolink:NamedThing	positive regulation of oskar mRNA translation	Any process that activates or increases the frequency, rate or extent of oskar mRNA translation.	got7fsn_ti	activation of oskar mRNA translation|up-regulation of oskar mRNA translation|stimulation of oskar mRNA translation|upregulation of oskar mRNA translation|up regulation of oskar mRNA translation													biological_process											owl:Class	
GO:0060910	biolink:NamedThing	negative regulation of DNA replication initiation involved in plasmid copy number maintenance	Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.	got7fsn_ti							dph	2009-09-04T02:56:29Z						biological_process											owl:Class	
GO:0032297	biolink:NamedThing	negative regulation of DNA-dependent DNA replication initiation	Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.	got7fsn_ti	inhibition of DNA replication initiation|down-regulation of DNA replication initiation|down regulation of DNA replication initiation|downregulation of DNA replication initiation|negative regulation of DNA replication initiation													biological_process											owl:Class	
GO:0071903	biolink:NamedThing	protein N-linked N-acetylglucosaminylation via asparagine	A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue.	got7fsn_ti	protein amino acid N-linked N-acetylglucosaminylation via asparagine						mah	2010-09-15T03:49:16Z				RESID:AA0151		biological_process											owl:Class	
GO:0018279	biolink:NamedThing	protein N-linked glycosylation via asparagine	The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.	got7fsn_ti	protein amino acid N-linked glycosylation via asparagine													biological_process											owl:Class	
GO:0090649	biolink:NamedThing	response to oxygen-glucose deprivation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.	got7fsn_ti	response to OGD						tb	2015-07-01T10:27:29Z						biological_process											owl:Class	
GO:0036293	biolink:NamedThing	response to decreased oxygen levels	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.	got7fsn_ti	response to lowered oxygen levels				This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'.		bf	2012-07-20T01:05:46Z						biological_process											owl:Class	
GO:0090353	biolink:NamedThing	polygalacturonase inhibitor activity	Binds to and stops, prevents or reduces the activity of polygalacturonase.	got7fsn_ti							tb	2010-06-15T04:19:49Z						molecular_function											owl:Class	
GO:0004857	biolink:NamedThing	enzyme inhibitor activity	Binds to and stops, prevents or reduces the activity of an enzyme.	got7fsn_ti	metalloenzyme inhibitor activity				This term should only be used in cases when the regulator directly interacts with the enzyme.						GO:0048551			molecular_function											owl:Class	
GO:0044019	biolink:NamedThing	histone acetyltransferase activity (H3-K72 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K72 specific)													molecular_function											owl:Class	
GO:0010484	biolink:NamedThing	H3 histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3.	got7fsn_ti														molecular_function											owl:Class	
GO:0060946	biolink:NamedThing	cardiac blood vessel endothelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.	got7fsn_ti							dph	2009-09-29T02:48:55Z						biological_process											owl:Class	
GO:0060837	biolink:NamedThing	blood vessel endothelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.	got7fsn_ti							dph	2009-08-11T03:47:36Z						biological_process											owl:Class	
GO:0035266	biolink:NamedThing	meristem growth	The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0097207	biolink:NamedThing	bud dormancy process	A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud.	got7fsn_ti	bud dormancy				Bud dormancy may precede dormancy of the whole plant.		pr	2012-01-04T01:18:24Z						biological_process											owl:Class	
GO:0050119	biolink:NamedThing	N-acetylglucosamine deacetylase activity	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate.	got7fsn_ti	acetylaminodeoxyglucose acetylhydrolase activity|N-acetyl-D-glucosamine amidohydrolase activity|N-acetyl-D-glucosaminyl N-deacetylase activity											RHEA:20593|MetaCyc:N-ACETYLGLUCOSAMINE-DEACETYLASE-RXN|KEGG_REACTION:R01200|EC:3.5.1.33|Reactome:R-HSA-2022887		molecular_function											owl:Class	
GO:0106003	biolink:NamedThing	amyloid-beta complex	Protein complex involved in modulation of signaling and synaptic function in the brain, predominantly in the cerebral cortex and hippocampus. Forms dimers and multimers of amyloid beta peptide 40 and peptide 42 (proteolytic cleavage products of amyloid beta A4 protein, also known as amyloid beta precursor protein). Mostly found in the extracellular space with a proportion occurring as membrane-bound species. Influences synaptic plasticity through various receptors, mediates dendritic spine loss leading to decreased synapse density, inhibits long-term potentiation (LTP) and enhances long-term depression (LTD). Soluble multimeric form is the main pathogenic species linked to Alzheimer's disease.	got7fsn_ti	amyloid-beta protein 40 complex|heterodimer of amyloid beta protein|beta-amyloid complex|heterooligomer of amyloid beta protein|amyloid beta heterotrimer|Abeta-derived diffusible ligand complex|amyloid beta homodimer|amyloid beta complex|amyloid beta dimer|betaA complex|amyloid beta heterodimer|ADDL complex|amyloid-beta protein 42 complex|homodimer of amyloid beta protein|amyloid beta trimer|amyloid beta heterooligomer|amyloid beta homotrimer|homotrimer of amyloid beta protein|amyloid beta oligomer|homooligomer of amyloid beta protein|heterotrimer of amyloid beta protein|amyloid beta homooligomer|amyloid-beta protein 40/42 complex|beta amyloid complex|Abeta complex				An example is Protein 40 of APP (P05067-PRO_0000000093) in PMID:18568035 (inferred by direct assay).		hjd	2017-03-15T19:19:29Z						cellular_component											owl:Class	
GO:1990012	biolink:NamedThing	complex laminated body	A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint.	got7fsn_ti	CLB						pr	2012-12-12T14:18:15Z				NIF_Subcellular:nlx_151681		cellular_component											owl:Class	
GO:1990011	biolink:NamedThing	laminated body	Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus.	got7fsn_ti	laminated inclusion body						pr	2012-12-12T14:12:21Z				NIF_Subcellular:sao506721981		cellular_component											owl:Class	
GO:0002266	biolink:NamedThing	follicular dendritic cell activation	A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	got7fsn_ti														biological_process											owl:Class	
GO:0004499	biolink:NamedThing	N,N-dimethylaniline monooxygenase activity	Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.	got7fsn_ti	dimethylaniline oxidase activity|flavin mixed function oxidase activity|N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming)|FMO5|1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity|FMO-I|dimethylaniline monooxygenase (N-oxide-forming) activity|mixed-function amine oxidase activity|FMO activity|Ziegler's enzyme|FMO1|FMO-II|DMA oxidase activity|FAD-containing monooxygenase activity|flavin monooxygenase activity|flavin-containing monooxygenase activity|FMO3|methylphenyltetrahydropyridine N-monooxygenase activity|dimethylaniline N-oxidase activity|FMO2|FMO4										GO:0047076	Reactome:R-HSA-5602966|Reactome:R-HSA-217255|MetaCyc:1.14.13.8-RXN|EC:1.14.13.8|Reactome:R-HSA-139970|RHEA:24468		molecular_function											owl:Class	
GO:0018515	biolink:NamedThing	pimeloyl-CoA dehydrogenase activity	Catalysis of the reaction: NAD(+) + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H(+) + NADH.	got7fsn_ti	pimeloyl-CoA:NAD+ oxidoreductase activity											UM-BBD_reactionID:r0194|RHEA:19665|EC:1.3.1.62|MetaCyc:1.3.1.62-RXN|KEGG_REACTION:R05311		molecular_function											owl:Class	
GO:0031297	biolink:NamedThing	replication fork processing	The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.	got7fsn_ti	recovery from replication fork stalling|replication fork restart|recovery from replication fork arrest at rDNA locus|replication restart|recovery from replication fork arrest|collapsed replication fork processing|replication fork processing at ribosomal DNA locus|replication fork processing at rDNA locus|recovery from replication fork stalling at rDNA locus										GO:0034065			biological_process											owl:Class	
GO:0045005	biolink:NamedThing	DNA-dependent DNA replication maintenance of fidelity	A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair.	got7fsn_ti	maintenance of fidelity during DNA-dependent DNA replication|maintenance of fidelity involved in DNA-dependent DNA replication													biological_process											owl:Class	
GO:0002221	biolink:NamedThing	pattern recognition receptor signaling pathway	Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.	got7fsn_ti	pathogen receptor signaling pathway|pathogen receptor signalling pathway|PRR signaling pathway|PAMP receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/18588												biological_process											owl:Class	
GO:0002764	biolink:NamedThing	immune response-regulating signaling pathway	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.	got7fsn_ti	immune response-regulating signalling pathway													biological_process											owl:Class	
GO:0004743	biolink:NamedThing	pyruvate kinase activity	Catalysis of the reaction: = ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate.	got7fsn_ti	phosphoenol transphosphorylase activity|phosphoenolpyruvate kinase activity|ATP:pyruvate 2-O-phosphotransferase activity											MetaCyc:PEPDEPHOS-RXN|RHEA:18159|EC:2.7.1.40|Reactome:R-HSA-71670		molecular_function											owl:Class	
GO:0048482	biolink:NamedThing	plant ovule morphogenesis	The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.	got7fsn_ti														biological_process											owl:Class	
GO:0002445	biolink:NamedThing	type II hypersensitivity	An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.	got7fsn_ti												Wikipedia:Type_II_hypersensitivity		biological_process											owl:Class	
GO:0002444	biolink:NamedThing	myeloid leukocyte mediated immunity	Any process involved in the carrying out of an immune response by a myeloid leukocyte.	got7fsn_ti	myeloid leucocyte mediated immunity|myeloid leukocyte immune effector process|myeloid leucocyte immune effector process													biological_process											owl:Class	
GO:0099510	biolink:NamedThing	calcium ion binding involved in regulation of cytosolic calcium ion concentration	The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations.	got7fsn_ti	regulation of cytosolic calcium ion concentration by calcium ion buffering													molecular_function											owl:Class	
GO:0005509	biolink:NamedThing	calcium ion binding	Binding to a calcium ion (Ca2+).	got7fsn_ti	calcium ion storage activity													molecular_function											owl:Class	
GO:0010638	biolink:NamedThing	positive regulation of organelle organization	Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.	got7fsn_ti	positive regulation of organelle organisation|positive regulation of organelle organization and biogenesis													biological_process											owl:Class	
GO:0042736	biolink:NamedThing	NADH kinase activity	Catalysis of the reaction: ATP + NADH = ADP + 2 H(+) + NADPH.	got7fsn_ti	ATP:NADH 2'-phosphotransferase activity|DPNH kinase activity|reduced diphosphopyridine nucleotide kinase activity|reduced nicotinamide adenine dinucleotide kinase (phosphorylating)											RHEA:12260|EC:2.7.1.86|MetaCyc:NADH-KINASE-RXN|KEGG_REACTION:R00105		molecular_function											owl:Class	
GO:0044854	biolink:NamedThing	plasma membrane raft assembly	The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft.	got7fsn_ti							jl	2014-07-23T15:58:16Z						biological_process											owl:Class	
GO:0001765	biolink:NamedThing	membrane raft assembly	The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.	got7fsn_ti	membrane raft formation|lipid raft formation|lipid raft assembly													biological_process											owl:Class	
GO:0061549	biolink:NamedThing	sympathetic ganglion development	The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.	got7fsn_ti	sympathetic ganglia development						dph	2013-07-10T08:38:01Z						biological_process											owl:Class	
GO:0061548	biolink:NamedThing	ganglion development	The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.	got7fsn_ti	ganglia development|gangliogenesis						dph	2013-07-10T08:36:12Z						biological_process											owl:Class	
GO:0047684	biolink:NamedThing	arylamine glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine.	got7fsn_ti	UDP-glucose:arylamine N-D-glucosyltransferase activity|UDP glucose-arylamine glucosyltransferase activity|UDPglucose:arylamine N-D-glucosyltransferase activity|uridine diphosphoglucose-arylamine glucosyltransferase activity											EC:2.4.1.71|MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0019412	biolink:NamedThing	aerobic respiration, using hydrogen as electron donor	The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water.	got7fsn_ti	hydrogen oxidation											MetaCyc:P283-PWY		biological_process											owl:Class	
GO:0015975	biolink:NamedThing	energy derivation by oxidation of reduced inorganic compounds	The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.	got7fsn_ti	chemolithotrophy|chemolithotrophie|lithotrophy											Wikipedia:Lithotrophy		biological_process											owl:Class	
GO:0080073	biolink:NamedThing	spermidine:coumaroyl CoA N-acyltransferase activity	Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule.	got7fsn_ti							dhl	2009-04-13T04:16:59Z						molecular_function											owl:Class	
GO:0044160	biolink:NamedThing	host thylakoid membrane	The pigmented membrane of any host thylakoid.	got7fsn_ti							jl	2009-08-11T04:17:31Z						cellular_component											owl:Class	
GO:0005143	biolink:NamedThing	interleukin-12 receptor binding	Binding to an interleukin-12 receptor.	got7fsn_ti	interleukin-12 receptor ligand|IL-12													molecular_function											owl:Class	
GO:0050869	biolink:NamedThing	negative regulation of B cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.	got7fsn_ti	down-regulation of B cell activation|negative regulation of B lymphocyte activation|down regulation of B cell activation|downregulation of B cell activation|negative regulation of B-lymphocyte activation|negative regulation of B-cell activation|inhibition of B cell activation													biological_process											owl:Class	
GO:0060883	biolink:NamedThing	regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication	Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basement membrane disassembly involved in semicircular canal fusion.	got7fsn_ti	regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication						dph	2009-08-13T11:31:56Z						biological_process											owl:Class	
GO:0007154	biolink:NamedThing	cell communication	Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti												Wikipedia:Cell_signaling		biological_process											owl:Class	
GO:1902407	biolink:NamedThing	assembly of actomyosin apparatus involved in mitotic cytokinesis	Any assembly of mitotic cytokinetic actomyosin apparatus.	got7fsn_ti	actomyosin apparatus assembly involved in cytokinesis involved in mitotic cell cycle|formation of actomyosin apparatus involved in cytokinesis involved in mitotic cell cycle|cytokinesis, formation of actomyosin apparatus involved in mitotic cell cycle						jl	2013-09-12T12:28:22Z						biological_process											owl:Class	
GO:1902410	biolink:NamedThing	mitotic cytokinetic process	Any cytokinetic process that is involved in mitotic cell cycle.	got7fsn_ti							jl	2013-09-12T12:29:36Z						biological_process											owl:Class	
GO:0052879	biolink:NamedThing	9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity	Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate.	got7fsn_ti	(8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-5,8-dihydroxy-9,12-octadecadienoate-forming) activity|8-hydroperoxide isomerase activity|linoleate diol synthase activity											KEGG_REACTION:R07062|EC:5.4.4.6|MetaCyc:1.13.11.44-RXN|RHEA:25399		molecular_function											owl:Class	
GO:0050486	biolink:NamedThing	intramolecular transferase activity, transferring hydroxy groups	Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule.	got7fsn_ti												EC:5.4.4.-		molecular_function											owl:Class	
GO:0004964	biolink:NamedThing	luteinizing hormone receptor activity	Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity.	got7fsn_ti	LHR|lutropin-choriogonadotropic hormone receptor|lutropin receptor|LH receptor										GO:0004976			molecular_function											owl:Class	
GO:0044255	biolink:NamedThing	cellular lipid metabolic process	The chemical reactions and pathways involving lipids, as carried out by individual cells.	got7fsn_ti	cellular lipid metabolism													biological_process											owl:Class	
GO:0047153	biolink:NamedThing	deoxycytidylate 5-hydroxymethyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate.	got7fsn_ti	dCMP hydroxymethylase activity|deoxycytidylic hydroxymethylase activity|deoxyCMP hydroxymethylase activity|d-cytidine 5'-monophosphate hydroxymethylase activity|deoxycytidylate hydroxymethyltransferase activity|deoxycytidylate hydroxymethylase activity|5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase activity											MetaCyc:2.1.2.8-RXN|KEGG_REACTION:R01669|RHEA:11280|EC:2.1.2.8		molecular_function											owl:Class	
GO:0001737	biolink:NamedThing	establishment of imaginal disc-derived wing hair orientation	Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.	got7fsn_ti	establishment of wing hair orientation													biological_process											owl:Class	
GO:0001736	biolink:NamedThing	establishment of planar polarity	Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.	got7fsn_ti	establishment of planar cell polarity													biological_process											owl:Class	
GO:0007137	biolink:NamedThing	meiotic metaphase II	The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0051323	biolink:NamedThing	metaphase	The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Metaphase		biological_process											owl:Class	
GO:0002095	biolink:NamedThing	caveolar macromolecular signaling complex	A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).	got7fsn_ti	caveolar macromolecular signalling complex													cellular_component											owl:Class	
GO:0098510	biolink:NamedThing	sensory perception of high humidity	The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti							dos	2013-09-25T13:57:27Z						biological_process											owl:Class	
GO:0009960	biolink:NamedThing	endosperm development	The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0007428	biolink:NamedThing	primary branching, open tracheal system	Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster.	got7fsn_ti	primary tracheal branching													biological_process											owl:Class	
GO:0060446	biolink:NamedThing	branching involved in open tracheal system development	The process in which the anatomical structures of branches in the open tracheal system are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0006610	biolink:NamedThing	ribosomal protein import into nucleus	The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus.	got7fsn_ti	ribosomal protein import into cell nucleus|ribosomal protein transport from cytoplasm to nucleus|ribosomal protein-nucleus import	https://github.com/geneontology/go-annotation/issues/1700			Ribosomal protein rpl12 uses a different import pathway, which is why it has a separate GO term.									biological_process											owl:Class	
GO:0006606	biolink:NamedThing	protein import into nucleus	The directed movement of a protein from the cytoplasm to the nucleus.	got7fsn_ti	protein import into cell nucleus|establishment of protein localization to nucleus|protein transport from cytoplasm to nucleus|protein nucleus import													biological_process											owl:Class	
GO:0106228	biolink:NamedThing	peptide glutaryltransferase activity	Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein].	got7fsn_ti							hjd	2019-10-17T18:58:56Z				RHEA:18009		molecular_function											owl:Class	
GO:0019331	biolink:NamedThing	anaerobic respiration, using ammonium as electron donor	The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2.	got7fsn_ti	anaerobic ammonium oxidation|anammox											MetaCyc:P303-PWY|Wikipedia:Anammox		biological_process											owl:Class	
GO:0009061	biolink:NamedThing	anaerobic respiration	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.	got7fsn_ti												MetaCyc:ANARESP1-PWY|Wikipedia:Anaerobic_respiration|Wikipedia:Cellular_respiration#Anaerobic_respiration		biological_process											owl:Class	
GO:0047073	biolink:NamedThing	2,4'-dihydroxyacetophenone dioxygenase activity	Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O(2) = 4-hydroxybenzoate + formate + 2 H(+).	got7fsn_ti	2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving)|(4-hydroxybenzoyl)methanol oxygenase activity											EC:1.13.11.41|UM-BBD_reactionID:r1410|KEGG_REACTION:R01305|MetaCyc:1.13.11.41-RXN|RHEA:24416		molecular_function											owl:Class	
GO:0032782	biolink:NamedThing	bile acid secretion	The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0046717	biolink:NamedThing	acid secretion	The controlled release of acid by a cell or a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0002076	biolink:NamedThing	osteoblast development	The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.	got7fsn_ti														biological_process											owl:Class	
GO:0016475	biolink:NamedThing	detection of nuclear:cytoplasmic ratio	The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell.	got7fsn_ti	interpretation of nuclear:cytoplasmic ratio|sensing of nuclear:cytoplasmic ratio													biological_process											owl:Class	
GO:0009726	biolink:NamedThing	detection of endogenous stimulus	The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of endogenous stimulus													biological_process											owl:Class	
GO:0007584	biolink:NamedThing	response to nutrient	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.	got7fsn_ti	nutritional response pathway|response to nutrients													biological_process											owl:Class	
GO:0031667	biolink:NamedThing	response to nutrient levels	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.	got7fsn_ti														biological_process											owl:Class	
GO:0000716	biolink:NamedThing	transcription-coupled nucleotide-excision repair, DNA damage recognition	The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.	got7fsn_ti	pyrimidine-dimer repair, DNA damage recognition													biological_process											owl:Class	
GO:0000715	biolink:NamedThing	nucleotide-excision repair, DNA damage recognition	The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.	got7fsn_ti	pyrimidine-dimer repair, DNA damage recognition													biological_process											owl:Class	
GO:0050447	biolink:NamedThing	zeatin 9-aminocarboxyethyltransferase activity	Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H(+).	got7fsn_ti	O3-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity|O-acetyl-L-serine acetate-lyase (adding N(6)-substituted adenine) activity|lupinic acid synthetase activity|lupinic acid synthase activity|O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine)|lupinate synthetase activity|3-O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity|beta-(9-cytokinin)-alanine synthase activity|beta-(9-cytokinin)alanine synthase activity											EC:2.5.1.50|MetaCyc:BETA-9-CYTOKININ-ALANINE-SYNTHASE-RXN|RHEA:17333|KEGG_REACTION:R03133		molecular_function											owl:Class	
GO:0007438	biolink:NamedThing	oenocyte development	The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.	got7fsn_ti														biological_process											owl:Class	
GO:0050901	biolink:NamedThing	leukocyte tethering or rolling	Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12276#issuecomment-185260139|https://github.com/geneontology/go-ontology/issues/20174												biological_process											owl:Class	
GO:0031131	biolink:NamedThing	reception of an inductive signal	The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change.	got7fsn_ti														biological_process											owl:Class	
GO:0031668	biolink:NamedThing	cellular response to extracellular stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0001913	biolink:NamedThing	T cell mediated cytotoxicity	The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.	got7fsn_ti	T-lymphocyte mediated cytotoxicity|T cell mediated cell death|T-cell mediated cell death|T-cell mediated cell killing|T cell mediated cell killing|T lymphocyte mediated cytotoxicity|T-cell mediated cytotoxicity|T cell mediated cytolysis|T cell mediated apoptosis|T-cell mediated apoptosis				Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in the induction of apoptosis in the target cell. Note that both CD4 and CD8 positive T cells can mediate apoptosis of target cells, independently of their definition as 'helper' T cells or not.									biological_process											owl:Class	
GO:0036516	biolink:NamedThing	chemoattraction of dopaminergic neuron axon	The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.	got7fsn_ti	chemoattraction of DA axon|chemoattraction of dopaminergic axon						bf	2015-12-17T11:23:11Z						biological_process											owl:Class	
GO:0061642	biolink:NamedThing	chemoattraction of axon	The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal.	got7fsn_ti							dph	2014-08-29T08:21:24Z						biological_process											owl:Class	
GO:0003138	biolink:NamedThing	primary heart field specification	The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle.	got7fsn_ti	FHS specification|first heart field specification						tb	2009-09-22T03:47:24Z						biological_process											owl:Class	
GO:0003128	biolink:NamedThing	heart field specification	The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop.	got7fsn_ti							tb	2009-09-22T02:56:05Z						biological_process											owl:Class	
GO:0032451	biolink:NamedThing	demethylase activity	Catalysis of the removal of a methyl group from a substrate.	got7fsn_ti														molecular_function											owl:Class	
GO:0003824	biolink:NamedThing	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.	got7fsn_ti	enzyme activity											Wikipedia:Enzyme		molecular_function											owl:Class	
GO:0045037	biolink:NamedThing	protein import into chloroplast stroma	The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import.	got7fsn_ti	protein transport into chloroplast stroma|chloroplast stroma protein import													biological_process											owl:Class	
GO:0045036	biolink:NamedThing	protein targeting to chloroplast	The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved.	got7fsn_ti	protein-chloroplast targeting													biological_process											owl:Class	
GO:0072006	biolink:NamedThing	nephron development	The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.	got7fsn_ti	nephrogenesis						mah	2010-01-25T01:37:16Z						biological_process											owl:Class	
GO:0140315	biolink:NamedThing	iron ion sequestering activity	The selective interaction of a protein with an iron ion to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	got7fsn_ti							pg	2019-03-28T10:10:33Z						molecular_function											owl:Class	
GO:0005787	biolink:NamedThing	signal peptidase complex	A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.	got7fsn_ti														cellular_component											owl:Class	
GO:0047866	biolink:NamedThing	dimethylglycine oxidase activity	Catalysis of the reaction: N,N-dimethylglycine + H(2)O + O(2) = formaldehyde + H(2)O(2) + sarcosine.	got7fsn_ti	N,N-dimethylglycine:oxygen oxidoreductase (demethylating)											EC:1.5.3.10|KEGG_REACTION:R01564|MetaCyc:DIMETHYLGLYCINE-OXIDASE-RXN|RHEA:17077		molecular_function											owl:Class	
GO:0016647	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen.	got7fsn_ti												EC:1.5.3.-		molecular_function											owl:Class	
GO:0047177	biolink:NamedThing	glycerophospholipid arachidonoyl-transferase (CoA-independent) activity	Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine.	got7fsn_ti	1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)|1-organyl-2-arachidonyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)											EC:2.3.1.147|RHEA:15409|MetaCyc:2.3.1.147-RXN		molecular_function											owl:Class	
GO:0002569	biolink:NamedThing	somatic diversification of immune receptors by N region addition	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.	got7fsn_ti														biological_process											owl:Class	
GO:0009829	biolink:NamedThing	cell wall modification involved in fruit ripening	The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening.	got7fsn_ti	cell wall modification during ripening													biological_process											owl:Class	
GO:0022412	biolink:NamedThing	cellular process involved in reproduction in multicellular organism	A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.	got7fsn_ti	reproductive cellular process in multicellular organism													biological_process											owl:Class	
GO:0052769	biolink:NamedThing	beta-6-sulfate-N-acetylglucosaminidase activity	Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative.	got7fsn_ti	exosulfoglycosidase activity|sulfoglycosidase activity|sulfomucin beta-6-sulfate-N-acetylglucosaminidase activity|beta-6-SO3-N-acetylglucosaminidase activity						ai	2011-09-30T12:55:24Z						molecular_function											owl:Class	
GO:0042688	biolink:NamedThing	crystal cell differentiation	The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.	got7fsn_ti														biological_process											owl:Class	
GO:0042386	biolink:NamedThing	hemocyte differentiation	The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.	got7fsn_ti	arthropod blood cell differentiation													biological_process											owl:Class	
GO:0003943	biolink:NamedThing	N-acetylgalactosamine-4-sulfatase activity	Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.	got7fsn_ti	arylsulfatase B|chondroitinsulfatase|N-acetylgalactosamine-4-sulphatase activity|N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity|acetylgalactosamine 4-sulfatase activity|N-acetylgalactosamine 4-sulfate sulfohydrolase activity											Reactome:R-HSA-1606789|Reactome:R-HSA-1793207|Wikipedia:Arylsulfatase_B|Reactome:R-HSA-9036065|Reactome:R-HSA-2282889|EC:3.1.6.12|MetaCyc:3.1.6.12-RXN		molecular_function											owl:Class	
GO:0090561	biolink:NamedThing	nuclear migration during mitotic telophase	The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis.	got7fsn_ti							tb	2014-03-27T15:17:10Z						biological_process											owl:Class	
GO:0052759	biolink:NamedThing	coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity	Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction.	got7fsn_ti	coenzyme F420-dependent 2,4,6-trinitrophenol-hydride-Meisenheimer-complex hydride transferase activity							2011-09-28T01:50:17Z				UM-BBD_reactionID:r1066|EC:1.3.99.-		molecular_function											owl:Class	
GO:0071564	biolink:NamedThing	npBAF complex	A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.	got7fsn_ti							mah	2010-01-20T03:33:42Z						cellular_component											owl:Class	
GO:0030429	biolink:NamedThing	kynureninase activity	Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine.	got7fsn_ti	kynurenine hydrolase activity|L-kynurenine hydrolase activity											MetaCyc:KYNURENINASE-RXN|EC:3.7.1.3|Reactome:R-HSA-71217|RHEA:16813		molecular_function											owl:Class	
GO:0004852	biolink:NamedThing	uroporphyrinogen-III synthase activity	Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III.	got7fsn_ti	uroporphyrinogen-III cosynthase activity|uroporphyrinogen isomerase activity|URO-synthase activity|hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)|hydroxymethylbilane hydro-lyase (cyclizing) activity|porphobilinogenase activity|uroporphyrinogen-III cosynthetase activity|uroporphyrinogen III cosynthase activity											KEGG_REACTION:R03165|RHEA:18965|EC:4.2.1.75|MetaCyc:UROGENIIISYN-RXN|Reactome:R-HSA-189488		molecular_function											owl:Class	
GO:0030780	biolink:NamedThing	12-hydroxydihydrochelirubine 12-O-methyltransferase activity	Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase activity											MetaCyc:2.1.1.120-RXN|EC:2.1.1.120|RHEA:21092|KEGG_REACTION:R04705		molecular_function											owl:Class	
GO:0071347	biolink:NamedThing	cellular response to interleukin-1	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.	got7fsn_ti	cellular response to IL-1						mah	2009-12-11T02:49:17Z						biological_process											owl:Class	
GO:0070555	biolink:NamedThing	response to interleukin-1	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.	got7fsn_ti	response to IL-1													biological_process											owl:Class	
GO:0071847	biolink:NamedThing	TNFSF11-mediated signaling pathway	A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	RANKL-mediated signaling pathway|TNFSF11-mediated signalling pathway|tumor necrosis factor superfamily member 11-mediated signaling pathway|receptor activator of nuclear factor kappa-B ligand signaling pathway|TNF-related activation-induced cytokine-mediated signaling pathway						mah	2010-09-10T02:22:42Z						biological_process											owl:Class	
GO:0033209	biolink:NamedThing	tumor necrosis factor-mediated signaling pathway	A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	adipocytokine signaling pathway|tumor necrosis factor-mediated signalling pathway|TNF-alpha-mediated signaling pathway|tumor necrosis factor alpha-mediated signaling pathway													biological_process											owl:Class	
GO:0047361	biolink:NamedThing	phosphomannan mannosephosphotransferase activity	Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP.	got7fsn_ti	GDP-mannose:phosphomannan mannose phosphotransferase activity											MetaCyc:2.7.8.9-RXN|EC:2.7.8.9		molecular_function											owl:Class	
GO:0090464	biolink:NamedThing	histidine homeostasis	Any process involved in the maintenance of an internal steady state of histidine within an organism or cell.	got7fsn_ti							tb	2012-09-24T14:22:02Z						biological_process											owl:Class	
GO:0106145	biolink:NamedThing	scopoletin 8-hydroxylase activity	Catalyzes of the reaction: scopoletin + 2-oxoglutarate+O2=fraxetin +succinate+ CO2).	got7fsn_ti							hjd	2018-09-07T18:28:16Z				RHEA:57848|EC:1.14.11.60		molecular_function											owl:Class	
GO:0017003	biolink:NamedThing	protein-heme linkage	The covalent linkage of heme and a protein.	got7fsn_ti	protein-haem linkage													biological_process											owl:Class	
GO:0017006	biolink:NamedThing	protein-tetrapyrrole linkage	The covalent linking of a tetrapyrrole to a protein.	got7fsn_ti														biological_process											owl:Class	
GO:1904950	biolink:NamedThing	negative regulation of establishment of protein localization	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.	got7fsn_ti	down regulation of protein positioning|negative regulation of protein recruitment|down-regulation of protein positioning|negative regulation of establishment of protein localisation|down regulation of establishment of protein localization|downregulation of protein positioning|down regulation of protein recruitment|inhibition of protein positioning|negative regulation of protein positioning|down-regulation of establishment of protein localization|downregulation of establishment of protein localization|inhibition of establishment of protein localisation|down-regulation of establishment of protein localisation|down regulation of establishment of protein localisation|downregulation of establishment of protein localisation|inhibition of protein recruitment|downregulation of protein recruitment|down-regulation of protein recruitment|inhibition of establishment of protein localization						mec	2016-02-05T09:59:24Z						biological_process											owl:Class	
GO:0070201	biolink:NamedThing	regulation of establishment of protein localization	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.	got7fsn_ti	regulation of establishment of protein localisation													biological_process											owl:Class	
GO:0003255	biolink:NamedThing	endocardial precursor cell differentiation	The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate.	got7fsn_ti							dph	2009-10-15T12:09:43Z						biological_process											owl:Class	
GO:0010002	biolink:NamedThing	cardioblast differentiation	The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	cardiomyocyte generation|cardioblast cell differentiation|cardiac precursor cell differentiation													biological_process											owl:Class	
GO:0018520	biolink:NamedThing	cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.	got7fsn_ti	4-methylcyclohexa-3,5-diene-1,2-cis-diol-1-carboxylic acid dehydrogenase activity|cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+ oxidoreductase (decarboxylating)											EC:1.3.1.67|MetaCyc:1.3.1.67-RXN|UM-BBD_reactionID:r0179		molecular_function											owl:Class	
GO:0072557	biolink:NamedThing	IPAF inflammasome complex	An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.	got7fsn_ti							mah	2011-01-27T12:01:44Z						cellular_component											owl:Class	
GO:0061702	biolink:NamedThing	inflammasome complex	A cytosolic protein complex that is capable of activating caspase-1.	got7fsn_ti							dph	2015-05-08T14:30:54Z						cellular_component											owl:Class	
GO:0075284	biolink:NamedThing	asexual sporulation resulting in formation of a multicellular or syncytial spore	The formation of a multicellular or syncytial spore via septations derived from mitosis.	got7fsn_ti														biological_process											owl:Class	
GO:0075283	biolink:NamedThing	sporulation resulting in formation of a multicellular or syncytial spore	The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure.	got7fsn_ti	multicellular or syncytial spore formation by sporulation													biological_process											owl:Class	
GO:0008442	biolink:NamedThing	3-hydroxyisobutyrate dehydrogenase activity	Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.	got7fsn_ti												Reactome:R-HSA-70885|Reactome:R-HSA-508473|EC:1.1.1.31|MetaCyc:3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN|RHEA:17681		molecular_function											owl:Class	
GO:0050437	biolink:NamedThing	(-)-endo-fenchol synthase activity	Catalysis of the reaction: geranyl diphosphate + H(2)O = (-)-endo-fenchol + diphosphate.	got7fsn_ti	(-)-endo-fenchol cyclase activity|geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]|geranyl pyrophosphate:(-)-endo-fenchol cyclase activity											RHEA:20565|EC:4.2.3.10|MetaCyc:4.2.3.10-RXN|KEGG_REACTION:R02004		molecular_function											owl:Class	
GO:0034726	biolink:NamedThing	DNA replication-independent nucleosome disassembly	The controlled breakdown of nucleosomes outside the context of DNA replication.	got7fsn_ti														biological_process											owl:Class	
GO:0006337	biolink:NamedThing	nucleosome disassembly	The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0019426	biolink:NamedThing	bisulfite reduction	The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite.	got7fsn_ti	bisulphite reduction											MetaCyc:P224-PWY		biological_process											owl:Class	
GO:0019419	biolink:NamedThing	sulfate reduction	The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.	got7fsn_ti	sulphate reduction, APS pathway|assimilatory sulfate reduction|sulfate reduction, APS pathway|assimilatory sulphate reduction|sulphate reduction										GO:0019421			biological_process											owl:Class	
GO:0075041	biolink:NamedThing	positive regulation of establishment of turgor in appressorium	Any process that activates or increases the frequency, rate or extent of turgor formation in the symbiont appressorium.	got7fsn_ti														biological_process											owl:Class	
GO:0075018	biolink:NamedThing	positive regulation of appressorium formation	Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation.	got7fsn_ti	positive regulation of appressorium formation on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0052519	biolink:NamedThing	positive regulation by host of nutrient release from symbiont	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	upregulation by host of nutrient release from symbiont|up regulation by host of nutrient release from symbiont|up-regulation by host of nutrient release from symbiont|stimulation by host of nutrient release from symbiont|activation by host of nutrient release from symbiont|promotion of nutrient release from symbiont													biological_process											owl:Class	
GO:0052460	biolink:NamedThing	modulation by host of nutrient release from symbiont	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0070727	biolink:NamedThing	cellular macromolecule localization	Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.	got7fsn_ti	cellular macromolecule localisation						mah	2009-06-16T04:08:29Z						biological_process											owl:Class	
GO:0071207	biolink:NamedThing	histone pre-mRNA stem-loop binding	Binding to a conserved stem-loop structure found in histone pre-mRNAs.	got7fsn_ti							mah	2009-11-25T01:25:15Z						molecular_function											owl:Class	
GO:0036002	biolink:NamedThing	pre-mRNA binding	Binding to a pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.	got7fsn_ti	protein-coding primary transcript binding						bf	2011-09-16T10:23:37Z						molecular_function											owl:Class	
GO:1990604	biolink:NamedThing	IRE1-TRAF2-ASK1 complex	A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).	got7fsn_ti	ERN1-TRAF2-ASK1 complex						bf	2015-01-13T15:03:04Z						cellular_component											owl:Class	
GO:0072715	biolink:NamedThing	cellular response to selenite ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.	got7fsn_ti							mah	2012-04-19T02:47:50Z						biological_process											owl:Class	
GO:0000830	biolink:NamedThing	inositol hexakisphosphate 4-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0000828	biolink:NamedThing	inositol hexakisphosphate kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.	got7fsn_ti												Reactome:R-HSA-1855216|Reactome:R-HSA-1855207|Reactome:R-HSA-1855227		molecular_function											owl:Class	
GO:0005315	biolink:NamedThing	inorganic phosphate transmembrane transporter activity	Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti											GO:0005317			molecular_function											owl:Class	
GO:0015291	biolink:NamedThing	secondary active transmembrane transporter activity	Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.	got7fsn_ti	galactose/glucose (methylgalactoside) porter activity|secondary carrier-type facilitators|active transporter|porter activity|nitrite/nitrate porter activity|electrochemical potential-driven transporter activity|coupled carrier|porters|multidrug endosomal transmembrane transporter activity|heavy metal ion porter activity|ion-gradient-driven energizer activity|energizer of outer membrane receptor-mediated transport activity										GO:0015404|GO:0015290|GO:0015353|GO:0015570	TC:2.A|Reactome:R-HSA-199216		molecular_function											owl:Class	
GO:0044624	biolink:NamedThing	envenomation resulting in modulation of cell migration in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of cell migration in the bitten organism.	got7fsn_ti	envenomation resulting in regulation of cell migration in other organism						jl	2012-07-04T05:03:56Z						biological_process											owl:Class	
GO:0007342	biolink:NamedThing	fusion of sperm to egg plasma membrane involved in single fertilization	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.	got7fsn_ti	sperm-oocyte fusion													biological_process											owl:Class	
GO:0045026	biolink:NamedThing	plasma membrane fusion	The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell.	got7fsn_ti	cell-cell fusion|cell fusion										GO:0006947			biological_process											owl:Class	
GO:0038034	biolink:NamedThing	signal transduction in absence of ligand	A series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor.	got7fsn_ti	addiction receptor signaling pathway|basal signaling|negative signal transduction|signal transduction in absence of agonist|dependence receptor signaling pathway|non-classical signal transduction						bf	2011-10-26T02:21:03Z						biological_process											owl:Class	
GO:0098793	biolink:NamedThing	presynapse	The part of a synapse that is part of the presynaptic cell.	got7fsn_ti	presynaptic terminal													cellular_component											owl:Class	
GO:0062147	biolink:NamedThing	L-lysine 4-chlorinase activity	Catalysis of the reaction: 2-oxoglutarate + chloride + H(+) + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.	got7fsn_ti							dph	2019-09-02T17:01:46Z				RHEA:59884		molecular_function											owl:Class	
GO:0050498	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated.	got7fsn_ti												EC:1.14.20.-		molecular_function											owl:Class	
GO:1990109	biolink:NamedThing	rejection of pollen from other species	The process involved in the rejection of pollen of one species by cells in the stigma of another species.	got7fsn_ti	unilateral interspecific incompatibility						tb	2013-05-29T21:12:09Z						biological_process											owl:Class	
GO:0006223	biolink:NamedThing	uracil salvage	Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0046107	biolink:NamedThing	uracil biosynthetic process	The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.	got7fsn_ti	uracil synthesis|uracil anabolism|uracil formation|uracil biosynthesis													biological_process											owl:Class	
GO:0042953	biolink:NamedThing	lipoprotein transport	The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0006810	biolink:NamedThing	transport	The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.	got7fsn_ti	single-organism transport|small molecule transport|solute:solute exchange				Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport.		jl	2012-12-13T16:25:32Z			GO:0015460|GO:0015457|GO:0044765			biological_process											owl:Class	
GO:0051918	biolink:NamedThing	negative regulation of fibrinolysis	Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.	got7fsn_ti	down-regulation of fibrinolysis|downregulation of fibrinolysis|down regulation of fibrinolysis|inhibition of fibrinolysis													biological_process											owl:Class	
GO:0030194	biolink:NamedThing	positive regulation of blood coagulation	Any process that activates or increases the frequency, rate or extent of blood coagulation.	got7fsn_ti	stimulation of blood coagulation|up regulation of blood coagulation|upregulation of blood coagulation|activation of blood coagulation|up-regulation of blood coagulation													biological_process											owl:Class	
GO:0050005	biolink:NamedThing	isohexenylglutaconyl-CoA hydratase activity	Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H(2)O.	got7fsn_ti	isohexenylglutaconyl coenzyme A hydratase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]|3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase activity|beta-isohexenylglutaconyl-CoA-hydratase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase activity											KEGG_REACTION:R03493|RHEA:24144|UM-BBD_reactionID:r1167|MetaCyc:ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN|EC:4.2.1.57		molecular_function											owl:Class	
GO:0019384	biolink:NamedThing	caprolactam catabolic process	The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid.	got7fsn_ti	caprolactam catabolism|caprolactam breakdown|caprolactam degradation											MetaCyc:P621-PWY		biological_process											owl:Class	
GO:0008425	biolink:NamedThing	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	got7fsn_ti	coenzyme Q biosynthetic process methyltransferase activity|ubiquinone biosynthetic process methyltransferase activity|coenzyme Q biosynthesis methyltransferase activity|ubiquinone biosynthesis methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity											EC:2.1.1.-		molecular_function											owl:Class	
GO:0030580	biolink:NamedThing	quinone cofactor methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1).	got7fsn_ti														molecular_function											owl:Class	
GO:0021566	biolink:NamedThing	hypoglossal nerve development	The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	got7fsn_ti	cranial nerve XII development|cranial nerve 12 development|CN XII development													biological_process											owl:Class	
GO:0033166	biolink:NamedThing	hyaline layer	A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms.	got7fsn_ti														cellular_component											owl:Class	
GO:0044863	biolink:NamedThing	modulation by virus of host cell division	Any process where an infecting virus modulates the frequency, rate or extent of the physical partitioning and separation of its host's cell into daughter cells.	got7fsn_ti	regulation by virus of host cell division						jl	2014-08-05T16:30:03Z						biological_process											owl:Class	
GO:0072249	biolink:NamedThing	metanephric glomerular visceral epithelial cell development	The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	got7fsn_ti	metanephric podocyte development						mah	2010-03-19T03:46:26Z						biological_process											owl:Class	
GO:0072015	biolink:NamedThing	glomerular visceral epithelial cell development	The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.	got7fsn_ti	podocyte development						mah	2010-01-25T02:12:45Z						biological_process											owl:Class	
GO:0043766	biolink:NamedThing	Sep-tRNA:Cys-tRNA synthase activity	Catalysis of the reaction: O-phospho-L-seryl-tRNACys + sulfide = L-cysteinyl-tRNACys + phosphate.	got7fsn_ti	Sep-tRNA:Cys-tRNA synthetase activity|O-phosphoseryl-tRNA:cysteinyl-tRNA synthase activity|SepCysS											EC:2.5.1.73|RHEA:25686|MetaCyc:RXN-10719		molecular_function											owl:Class	
GO:0007164	biolink:NamedThing	establishment of tissue polarity	Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.	got7fsn_ti														biological_process											owl:Class	
GO:0016760	biolink:NamedThing	cellulose synthase (UDP-forming) activity	Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1).	got7fsn_ti	UDP-glucose-1,4-beta-glucan glucosyltransferase activity|UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|beta-1,4-glucosyltransferase activity|1,4-beta-glucan synthase activity|UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|UDPglucose-cellulose glucosyltransferase activity|beta-1,4-glucan synthase activity|GS-I|beta-1,4-glucan synthetase activity|UDPglucose-beta-glucan glucosyltransferase activity|UDP-glucose-beta-D-glucan glucosyltransferase activity|beta-glucan synthase activity|UDP-glucose-cellulose glucosyltransferase activity|glucan synthase activity|uridine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity|1,4-beta-D-glucan synthase activity|uridine diphosphoglucose-cellulose glucosyltransferase activity											MetaCyc:CELLULOSE-SYNTHASE-UDP-FORMING-RXN|RHEA:19929|EC:2.4.1.12		molecular_function											owl:Class	
GO:0016759	biolink:NamedThing	cellulose synthase activity	Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).	got7fsn_ti	cellulose synthetase activity													molecular_function											owl:Class	
GO:0009958	biolink:NamedThing	positive gravitropism	The orientation of plant parts towards gravity.	got7fsn_ti	root gravitropism													biological_process											owl:Class	
GO:0009630	biolink:NamedThing	gravitropism	The orientation of plant parts under the stimulation of gravity.	got7fsn_ti	geotropism											Wikipedia:Gravitropism		biological_process											owl:Class	
GO:0034770	biolink:NamedThing	histone H4-K20 methylation	The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.	got7fsn_ti	histone H4 K20 methylation|histone lysine H4 K20 methylation|histone H4K20me													biological_process											owl:Class	
GO:0034968	biolink:NamedThing	histone lysine methylation	The modification of a histone by addition of one or more methyl groups to a lysine residue.	got7fsn_ti														biological_process											owl:Class	
GO:0047399	biolink:NamedThing	glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity	Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate.	got7fsn_ti	6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase activity|alpha-glucose-1-phosphate phosphodiesterase activity											EC:3.1.4.51|MetaCyc:3.1.4.51-RXN|RHEA:18045		molecular_function											owl:Class	
GO:0004454	biolink:NamedThing	ketohexokinase activity	Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.	got7fsn_ti	ATP:D-fructose 1-phosphotransferase activity|hepatic fructokinase activity|ketohexokinase (phosphorylating)											Reactome:R-HSA-5656459|RHEA:18145|EC:2.7.1.3|MetaCyc:KETOHEXOKINASE-RXN|Reactome:R-HSA-70333		molecular_function											owl:Class	
GO:0040005	biolink:NamedThing	chitin-based cuticle attachment to epithelium	Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	cuticular attachment to epithelium													biological_process											owl:Class	
GO:0022404	biolink:NamedThing	molting cycle process	A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.	got7fsn_ti														biological_process											owl:Class	
GO:0047975	biolink:NamedThing	guanosine phosphorylase activity	Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate.	got7fsn_ti	guanosine:phosphate alpha-D-ribosyltransferase activity|guanosine:phosphate D-ribosyltransferase activity											EC:2.4.2.15|RHEA:13233|MetaCyc:GUANPHOSPHOR-RXN		molecular_function											owl:Class	
GO:0016763	biolink:NamedThing	pentosyltransferase activity	Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring pentosyl groups	https://github.com/geneontology/go-ontology/issues/20486										EC:2.4.2.-|Reactome:R-HSA-112265|Reactome:R-HSA-112266		molecular_function											owl:Class	
GO:0072169	biolink:NamedThing	specification of posterior mesonephric tubule identity	The process in which the tubules of the posterior mesonephros acquire their identity.	got7fsn_ti							mah	2010-02-26T01:54:06Z						biological_process											owl:Class	
GO:0072098	biolink:NamedThing	anterior/posterior pattern specification involved in kidney development	The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.	got7fsn_ti	kidney anterior/posterior pattern formation|anterior/posterior pattern formation involved in kidney development|kidney anterior/posterior pattern specification						mah	2010-02-10T02:06:24Z						biological_process											owl:Class	
GO:1990037	biolink:NamedThing	Lewy body core	The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments.	got7fsn_ti							pr	2013-02-08T12:56:59Z				NIF_Subcellular:sao6587439252		cellular_component											owl:Class	
GO:0031220	biolink:NamedThing	maltodextrin phosphorylase activity	Catalysis of the reaction: maltodextrin = glucose-1-phosphate.	got7fsn_ti												MetaCyc:RXN-9025|RHEA:29691|MetaCyc:RXN0-5182		molecular_function											owl:Class	
GO:0004645	biolink:NamedThing	1,4-alpha-oligoglucan phosphorylase activity	Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.	got7fsn_ti	1,4-alpha-glucan phosphorylase activity|1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase activity|granulose phosphorylase|polyphosphorylase activity|potato phosphorylase|starch phosphorylase|muscle phosphorylase a and b activity|myophosphorylase|muscle phosphorylase|glucan phosphorylase|amylopectin phosphorylase|alpha-glucan phosphorylase|glucosan phosphorylase|amylophosphorylase activity											MetaCyc:RXN-1826|EC:2.4.1.1		molecular_function											owl:Class	
GO:0061633	biolink:NamedThing	transport-coupled glycolytic process through glucose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.	got7fsn_ti							dph	2014-06-19T09:12:37Z						biological_process											owl:Class	
GO:0061620	biolink:NamedThing	glycolytic process through glucose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.	got7fsn_ti							dph	2014-04-14T09:17:48Z				MetaCyc:GLYCOLYSIS		biological_process											owl:Class	
GO:0016899	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule.	got7fsn_ti												EC:1.1.3.-		molecular_function											owl:Class	
GO:0034796	biolink:NamedThing	adipate-CoA ligase activity	Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-.	got7fsn_ti												UM-BBD_reactionID:r1060		molecular_function											owl:Class	
GO:0019886	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class II	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.	got7fsn_ti	exogenous peptide antigen processing and presentation via MHC class II|antigen processing, exogenous antigen via major histocompatibility complex class II|antigen presentation, exogenous antigen via MHC class II|antigen presentation, exogenous peptide antigen										GO:0048005|GO:0042591			biological_process											owl:Class	
GO:0002495	biolink:NamedThing	antigen processing and presentation of peptide antigen via MHC class II	The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.	got7fsn_ti	peptide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0018860	biolink:NamedThing	anthranilate-CoA ligase activity	Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.	got7fsn_ti	2-aminobenzoate-CoA ligase activity|anthranilate--CoA ligase activity|2-aminobenzoate coenzyme A ligase activity|anthranilate:CoA ligase (AMP-forming)|anthraniloyl coenzyme A synthetase activity|2-aminobenzoate-coenzyme A ligase activity											EC:6.2.1.32|MetaCyc:AMINOBENZCOALIG-RXN|UM-BBD_reactionID:r0341|KEGG_REACTION:R00982|RHEA:10828		molecular_function											owl:Class	
GO:0017186	biolink:NamedThing	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.	got7fsn_ti	peptidyl-pyroglutamic acid anabolism, using glutaminyl-peptide cyclotransferase|peptidyl-pyroglutamic acid formation, using glutaminyl-peptide cyclotransferase|peptidyl-pyroglutamic acid synthesis, using glutaminyl-peptide cyclotransferase|2-pyrrolidone-5-carboxylic acid biosynthetic process|2-pyrrolidone-5-carboxylic acid biosynthesis				See also the molecular function term 'glutaminyl-peptide cyclotransferase activity ; GO:0016603'.							RESID:AA0031		biological_process											owl:Class	
GO:0051267	biolink:NamedThing	CP2 mannose-ethanolamine phosphotransferase activity	Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.	got7fsn_ti	CP2 phosphoethanolamine transferase activity|gpi7 activity|CP2 EtN-P transferase activity|CP2 ethanolamine phosphate transferase activity|addition of ethanolamine phosphate to mannose of GPI precursor CP2													molecular_function											owl:Class	
GO:0051377	biolink:NamedThing	mannose-ethanolamine phosphotransferase activity	Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.	got7fsn_ti	phosphoethanolamine transferase activity|EtN-P transferase activity|addition of ethanolamine phosphate to mannose of GPI precursor|ethanolamine phosphate transferase activity											Reactome:R-HSA-162798		molecular_function											owl:Class	
GO:0002941	biolink:NamedThing	synoviocyte proliferation	The multiplication or reproduction of synoviocytes by cell division, resulting in the expansion of their population. A synoviocyte is a fibroblast-like cell found in synovial tissues.	got7fsn_ti							hjd	2012-11-16T14:25:45Z						biological_process											owl:Class	
GO:0018362	biolink:NamedThing	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester	The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester.	got7fsn_ti	peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester										GO:0019924	RESID:AA0279		biological_process											owl:Class	
GO:0007275	biolink:NamedThing	multicellular organism development	The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21234			Note that this term was 'developmental process'.									biological_process											owl:Class	
GO:0033456	biolink:NamedThing	GCG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GCG codon.	got7fsn_ti	alanine tRNA				Note that in the standard genetic code, GCG codes for alanine.									molecular_function											owl:Class	
GO:0004495	biolink:NamedThing	mevaldate reductase activity	Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0051124	biolink:NamedThing	synaptic assembly at neuromuscular junction	The assembly of a synapse at a neuromuscular junction.	got7fsn_ti	cholinergic synaptogenesis|synaptic growth at neuromuscular junction													biological_process											owl:Class	
GO:0007416	biolink:NamedThing	synapse assembly	The aggregation, arrangement and bonding together of a set of components to form a synapse.  This process ends when the synapse is mature (functional).	got7fsn_ti	synapse biogenesis|synaptogenesis											Wikipedia:Synaptogenesis		biological_process											owl:Class	
GO:0060618	biolink:NamedThing	nipple development	The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.	got7fsn_ti							dph	2009-05-18T09:29:38Z						biological_process											owl:Class	
GO:0071929	biolink:NamedThing	alpha-tubulin acetylation	The addition of an acetyl group to the lysine 40 residue of alpha-tubulin.	got7fsn_ti							mah	2010-09-28T01:46:38Z						biological_process											owl:Class	
GO:0018393	biolink:NamedThing	internal peptidyl-lysine acetylation	The addition of an acetyl group to a non-terminal lysine residue in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0009323	biolink:NamedThing	ribosomal-protein-alanine N-acetyltransferase complex	An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine.	got7fsn_ti												EC:2.3.1.128		cellular_component											owl:Class	
GO:0099080	biolink:NamedThing	supramolecular complex	A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.	got7fsn_ti														cellular_component											owl:Class	
GO:0001697	biolink:NamedThing	histamine-induced gastric acid secretion	The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP.	got7fsn_ti														biological_process											owl:Class	
GO:0019684	biolink:NamedThing	photosynthesis, light reaction	The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I.	got7fsn_ti	photolysis											Wikipedia:Photolysis#Photolysis_in_photosynthesis|MetaCyc:PWY-101		biological_process											owl:Class	
GO:0035802	biolink:NamedThing	adrenal cortex formation	The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).	got7fsn_ti	adrenal gland cortex formation						bf	2011-04-18T10:26:49Z						biological_process											owl:Class	
GO:0071155	biolink:NamedThing	G-protein alpha(13)-synembrin complex	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein.	got7fsn_ti	Ric-8A G alpha 13 subunit complex						mah	2009-11-16T05:01:55Z						cellular_component											owl:Class	
GO:1990584	biolink:NamedThing	cardiac Troponin complex	A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction.	got7fsn_ti	cTnC:cTnI:cTnT						ame	2014-12-12T16:51:41Z						cellular_component											owl:Class	
GO:0005861	biolink:NamedThing	troponin complex	A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction.	got7fsn_ti														cellular_component											owl:Class	
GO:0016715	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor.	got7fsn_ti												EC:1.14.17.-		molecular_function											owl:Class	
GO:0019037	biolink:NamedThing	viral assembly intermediate	Specific locations and structures in the virus infected cell involved in assembling new virions.	got7fsn_ti														cellular_component											owl:Class	
GO:0062039	biolink:NamedThing	biofilm matrix	A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells.	got7fsn_ti							dph	2018-05-04T12:49:17Z						cellular_component											owl:Class	
GO:0031012	biolink:NamedThing	extracellular matrix	A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.	got7fsn_ti	matrisome|proteinaceous extracellular matrix										GO:0005578	NIF_Subcellular:nlx_subcell_20090513|Wikipedia:Extracellular_matrix		cellular_component											owl:Class	
GO:0031296	biolink:NamedThing	B cell costimulation	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation.	got7fsn_ti	B cell co-stimulation|B-lymphocyte co-stimulation|B lymphocyte costimulation|B-cell costimulation|B lymphocyte co-stimulation|B-cell co-stimulation|B-lymphocyte costimulation													biological_process											owl:Class	
GO:0031294	biolink:NamedThing	lymphocyte costimulation	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation.	got7fsn_ti	lymphocyte co-stimulation													biological_process											owl:Class	
GO:0051365	biolink:NamedThing	cellular response to potassium ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.	got7fsn_ti	cellular response to potassium ion deprivation|cellular response to potassium starvation|cellular response to K+ ion deprivation|cellular response to K+ ion starvation													biological_process											owl:Class	
GO:1900048	biolink:NamedThing	positive regulation of hemostasis	Any process that activates or increases the frequency, rate or extent of hemostasis.	got7fsn_ti	upregulation of hemostasis|up-regulation of hemostasis|activation of hemostasis|up regulation of hemostasis						jl	2012-01-19T03:23:45Z						biological_process											owl:Class	
GO:0102322	biolink:NamedThing	2-propylphenol monooxygenase activity	Catalysis of the reaction: 2-propylphenol + O2 + NADH + H+ = 3-propylcatechol + H2O + NAD.	got7fsn_ti												MetaCyc:RXN-13151|RHEA:63524		molecular_function											owl:Class	
GO:0071274	biolink:NamedThing	isoquinoline alkaloid catabolic process	The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.	got7fsn_ti	isoquinoline alkaloid breakdown|isoquinoline alkaloid catabolism|ipecac alkaloid catabolism|isoquinoline alkaloid degradation						mah	2009-12-10T11:17:49Z						biological_process											owl:Class	
GO:0046700	biolink:NamedThing	heterocycle catabolic process	The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).	got7fsn_ti	heterocycle catabolism|heterocycle breakdown|heterocycle degradation													biological_process											owl:Class	
GO:0048481	biolink:NamedThing	plant ovule development	The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.	got7fsn_ti														biological_process											owl:Class	
GO:0005251	biolink:NamedThing	delayed rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.	got7fsn_ti												Reactome:R-HSA-5577050|Reactome:R-HSA-5577237		molecular_function											owl:Class	
GO:0106318	biolink:NamedThing	methane monooxygenase NADPH activity	Catalysis of the reaction: methane + NADPH + H+ + O2 = methanol + NADP+ + H2O.	got7fsn_ti							hjd	2020-09-23T15:12:49Z				EC:1.14.13.25|RHEA:13641		molecular_function											owl:Class	
GO:0072461	biolink:NamedThing	response to meiotic recombination checkpoint signaling	A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling.	got7fsn_ti	meiotic recombination checkpoint effector process|response to signal involved in meiotic recombination checkpoint						mah	2010-12-09T11:37:01Z						biological_process											owl:Class	
GO:0072410	biolink:NamedThing	response to meiotic cell cycle checkpoint signaling	A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint.	got7fsn_ti	response to signal involved in meiotic cell cycle checkpoint|meiotic cell cycle checkpoint effector process						mah	2010-12-08T03:48:38Z						biological_process											owl:Class	
GO:0035487	biolink:NamedThing	thymine/thymine mispair binding	Binding to a double-stranded DNA region containing a T/T mispair.	got7fsn_ti	T/T mispair binding						bf	2010-04-23T10:56:37Z						molecular_function											owl:Class	
GO:0106026	biolink:NamedThing	Gly-tRNA(Ala) hydrolase activity	Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala).	got7fsn_ti							hjd	2017-06-16T17:13:33Z						molecular_function											owl:Class	
GO:0002161	biolink:NamedThing	aminoacyl-tRNA editing activity	The hydrolysis of an incorrectly aminoacylated tRNA.	got7fsn_ti	aminoacyl-tRNA hydrolysis activity|amino acid proofreading activity						hjd	2010-02-12T03:06:56Z						molecular_function											owl:Class	
GO:0048408	biolink:NamedThing	epidermal growth factor binding	Binding to epidermal growth factor.	got7fsn_ti	EGF binding													molecular_function											owl:Class	
GO:0042562	biolink:NamedThing	hormone binding	Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0075321	biolink:NamedThing	oomycete sporangium development	The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated.	got7fsn_ti														biological_process											owl:Class	
GO:0043582	biolink:NamedThing	sporangium development	The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores.	got7fsn_ti	sporangia development													biological_process											owl:Class	
GO:0043510	biolink:NamedThing	activin B complex	A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B).	got7fsn_ti					Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'.						GO:0048182			cellular_component											owl:Class	
GO:0048180	biolink:NamedThing	activin complex	A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit.	got7fsn_ti					Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'.									cellular_component											owl:Class	
GO:0050163	biolink:NamedThing	oxaloacetate tautomerase activity	Catalysis of the reaction: oxaloacetate = <stereo>enol</stereo>-oxaloacetate.	got7fsn_ti	oxaloacetate keto-enol tautomerase activity|oxaloacetate keto-enol-isomerase activity|oxalacetic keto-enol isomerase activity											KEGG_REACTION:R00363|RHEA:16021|EC:5.3.2.2|MetaCyc:OXALOACETATE-TAUTOMERASE-RXN		molecular_function											owl:Class	
GO:0016862	biolink:NamedThing	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears.	got7fsn_ti	intramolecular isomerase activity, interconverting keto- and enol-groups											EC:5.3.2.-		molecular_function											owl:Class	
GO:0001025	biolink:NamedThing	RNA polymerase III general transcription initiation factor binding	Binding to an RNA polymerase III transcription factor, a protein required to initiate or regulate transcription by RNA polymerase III.	got7fsn_ti	RNA polymerase III transcription factor binding						krc	2010-08-20T03:26:50Z						molecular_function											owl:Class	
GO:0140296	biolink:NamedThing	general transcription initiation factor binding	Binding to a general transcription initiation factor, a protein that contributes to transcription start site selection and transcription initiation.	got7fsn_ti							pg	2018-11-28T12:48:06Z						molecular_function											owl:Class	
GO:0005292	biolink:NamedThing	high-affinity lysine transmembrane transporter activity	Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity lysine transporter activity|high affinity lysine transmembrane transporter activity													molecular_function											owl:Class	
GO:0005287	biolink:NamedThing	high-affinity basic amino acid transmembrane transporter activity	Enables the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity basic amino acid transmembrane transporter activity|high-affinity basic amino acid transporter activity													molecular_function											owl:Class	
GO:0102788	biolink:NamedThing	4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	Catalysis of the reaction: 4-coumaryl-CoA + pelargonidin 3-O-beta-D-glucoside = pelargonidin 3-O-beta-D-p-coumaroylglucoside + coenzyme A.	got7fsn_ti												MetaCyc:RXN-7998		molecular_function											owl:Class	
GO:0002009	biolink:NamedThing	morphogenesis of an epithelium	The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.	got7fsn_ti	epithelium morphogenesis													biological_process											owl:Class	
GO:0051567	biolink:NamedThing	histone H3-K9 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.	got7fsn_ti	histone H3 K9 methylation|histone lysine H3 K9 methylation|histone H3K9me													biological_process											owl:Class	
GO:0061647	biolink:NamedThing	histone H3-K9 modification	The modification of histone H3 at a lysine in position 9 of the histone.	got7fsn_ti							dph	2014-10-02T15:07:42Z						biological_process											owl:Class	
GO:0047329	biolink:NamedThing	phosphoramidate-hexose phosphotransferase activity	Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3.	got7fsn_ti	phosphoramidate:hexose 1-phosphotransferase activity|phosphoramidate-hexose transphosphorylase activity|phosphoramidic-hexose transphosphorylase activity											RHEA:10972|EC:2.7.1.62|MetaCyc:2.7.1.62-RXN		molecular_function											owl:Class	
GO:0050986	biolink:NamedThing	isopeptide cross-linking via N-(L-isoglutamyl)-glycine	The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25.	got7fsn_ti												RESID:AA0360		biological_process											owl:Class	
GO:0018262	biolink:NamedThing	isopeptide cross-linking	The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon.	got7fsn_ti														biological_process											owl:Class	
GO:0060022	biolink:NamedThing	hard palate development	The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.	got7fsn_ti	palatum durum development													biological_process											owl:Class	
GO:0005121	biolink:NamedThing	Toll binding	Binding to a Toll protein, a transmembrane receptor.	got7fsn_ti	Toll ligand|Tl binding|Toll receptor binding													molecular_function											owl:Class	
GO:0106110	biolink:NamedThing	vomitoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats.	got7fsn_ti	vomitoxin formation|vomitoxin anabolism|deoxynivalenol biosynthetic process|vomitoxin biosynthesis|vomitoxin synthesis|DON biosynthetic process						hjd	2018-04-16T19:06:06Z						biological_process											owl:Class	
GO:0043386	biolink:NamedThing	mycotoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.	got7fsn_ti	mycotoxin biosynthesis|mycotoxin formation|mycotoxin synthesis|mycotoxin anabolism													biological_process											owl:Class	
GO:0007308	biolink:NamedThing	oocyte construction	The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte arrangement										GO:0048110			biological_process											owl:Class	
GO:0070925	biolink:NamedThing	organelle assembly	The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.	got7fsn_ti							mah	2009-09-15T03:00:51Z						biological_process											owl:Class	
GO:0034955	biolink:NamedThing	2,3-dihydroxydiphenyl ether dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol.	got7fsn_ti												UM-BBD_reactionID:r1451|EC:1.13.11.-		molecular_function											owl:Class	
GO:0034084	biolink:NamedThing	steryl deacetylase activity	Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol.	got7fsn_ti	sterol deacetylase activity													molecular_function											owl:Class	
GO:0019213	biolink:NamedThing	deacetylase activity	Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.	got7fsn_ti												Reactome:R-HSA-5689000		molecular_function											owl:Class	
GO:0001941	biolink:NamedThing	postsynaptic membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).	got7fsn_ti	postsynaptic membrane organisation|post-synaptic membrane organization													biological_process											owl:Class	
GO:0004413	biolink:NamedThing	homoserine kinase activity	Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H(+).	got7fsn_ti	homoserine kinase (phosphorylating)|ATP:L-homoserine O-phosphotransferase activity|HSK											RHEA:13985|EC:2.7.1.39|MetaCyc:HOMOSERKIN-RXN|KEGG_REACTION:R01771		molecular_function											owl:Class	
GO:0007051	biolink:NamedThing	spindle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.	got7fsn_ti	spindle organization and biogenesis|spindle stabilization|spindle organisation										GO:0043146			biological_process											owl:Class	
GO:0047890	biolink:NamedThing	flavanone 4-reductase activity	Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH.	got7fsn_ti	flavonone 4-reductase activity|(2S)-flavan-4-ol:NADP+ 4-oxidoreductase activity											EC:1.1.1.234|MetaCyc:FLAVANONE-4-REDUCTASE-RXN|RHEA:11228		molecular_function											owl:Class	
GO:0000121	biolink:NamedThing	glycerol-1-phosphatase activity	Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate.	got7fsn_ti	glycerol-1-phosphate phosphohydrolase activity|alpha-glycerophosphatase activity|glycerol 3-phosphatase activity|alpha-glycerol phosphatase activity|glycerol-3-phosphate phosphatase activity|glycerol 3-phosphate phosphohydrolase activity											RHEA:11476|MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN|EC:3.1.3.21		molecular_function											owl:Class	
GO:0044340	biolink:NamedThing	canonical Wnt signaling pathway involved in regulation of cell proliferation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to modulating the rate or frequency of cell proliferation.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in regulation of cell proliferation|canonical Wnt receptor signalling pathway involved in regulation of cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of cell proliferation						jl	2010-08-20T03:57:25Z						biological_process											owl:Class	
GO:0034620	biolink:NamedThing	cellular response to unfolded protein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	got7fsn_ti	heat shock protein activity				Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to the signaling pathways that respond to the presence of unfolded proteins in the ER.									biological_process											owl:Class	
GO:0006986	biolink:NamedThing	response to unfolded protein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	got7fsn_ti	heat shock protein activity				Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to one specific response to the presence of unfolded proteins in the ER.									biological_process											owl:Class	
GO:0007311	biolink:NamedThing	maternal specification of dorsal/ventral axis, oocyte, germ-line encoded	Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster.	got7fsn_ti	maternal specification of dorsal-ventral axis, oocyte, germ-line encoded|maternal determination of dorsal/ventral axis, oocyte, germ-line encoded|maternal specification of dorsoventral axis, oocyte, germ-line encoded										GO:0048124			biological_process											owl:Class	
GO:1901360	biolink:NamedThing	organic cyclic compound metabolic process	The chemical reactions and pathways involving organic cyclic compound.	got7fsn_ti	organic cyclic compound metabolism						bf	2012-09-14T09:03:51Z						biological_process											owl:Class	
GO:0071704	biolink:NamedThing	organic substance metabolic process	The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.	got7fsn_ti	organic molecular entity metabolic process|organic substance metabolism|organic molecular entity metabolism						mah	2010-03-08T03:32:18Z						biological_process											owl:Class	
GO:0030539	biolink:NamedThing	male genitalia development	The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.	got7fsn_ti	male genital development													biological_process											owl:Class	
GO:0030651	biolink:NamedThing	peptide antibiotic biosynthetic process	The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity.	got7fsn_ti	peptide antibiotic anabolism|peptide antibiotic synthesis|peptide antibiotic formation|peptide antibiotic biosynthesis													biological_process											owl:Class	
GO:0043043	biolink:NamedThing	peptide biosynthetic process	The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.	got7fsn_ti	peptide anabolism|peptide synthesis|peptide formation|peptide biosynthesis													biological_process											owl:Class	
GO:0003935	biolink:NamedThing	GTP cyclohydrolase II activity	Catalysis of the reaction: GTP + 3 H(2)O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H(+).	got7fsn_ti	GTP 7,8-8,9-dihydrolase (diphosphate-forming)|GTP-8-formylhydrolase activity|guanosine triphosphate cyclohydrolase II											EC:3.5.4.25|RHEA:23704|MetaCyc:GTP-CYCLOHYDRO-II-RXN|KEGG_REACTION:R00425		molecular_function											owl:Class	
GO:0003933	biolink:NamedThing	GTP cyclohydrolase activity	Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.	got7fsn_ti														molecular_function											owl:Class	
GO:0034217	biolink:NamedThing	ascospore wall chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.	got7fsn_ti	ascospore wall chitin synthesis|ascospore wall chitin anabolism|ascospore wall chitin formation|ascospore wall chitin biosynthesis													biological_process											owl:Class	
GO:0044106	biolink:NamedThing	cellular amine metabolic process	The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.	got7fsn_ti							jl	2009-07-15T11:55:44Z						biological_process											owl:Class	
GO:0034579	biolink:NamedThing	(1-methylpentyl)succinate synthase activity	Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate.	got7fsn_ti												UM-BBD_reactionID:r0920		molecular_function											owl:Class	
GO:0009100	biolink:NamedThing	glycoprotein metabolic process	The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	got7fsn_ti	glycoprotein metabolism													biological_process											owl:Class	
GO:0050243	biolink:NamedThing	pyruvate dehydrogenase (NADP+) activity	Catalysis of the reaction: CoA + NADP(+) + pyruvate = acetyl-CoA + CO(2) + NADPH.	got7fsn_ti	pyruvate:NADP+ oxidoreductase activity|pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)|pyruvate:NADP(+) oxidoreductase activity											RHEA:17425|EC:1.2.1.51|MetaCyc:PYRUVATE-DEHYDROGENASE-NADP%2b-RXN|KEGG_REACTION:R00210		molecular_function											owl:Class	
GO:0034603	biolink:NamedThing	pyruvate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H.	got7fsn_ti														molecular_function											owl:Class	
GO:0061568	biolink:NamedThing	GDP phosphorylation	The process of introducing a phosphate group into GDP, guanosine diphosphate, to produce GTP.	got7fsn_ti							dph	2013-08-01T12:57:12Z						biological_process											owl:Class	
GO:0072697	biolink:NamedThing	protein localization to cell cortex	A process in which a protein is transported to, or maintained in, the cell cortex.	got7fsn_ti	protein localisation to cell cortex						mah	2012-04-11T01:16:33Z						biological_process											owl:Class	
GO:0097489	biolink:NamedThing	multivesicular body, internal vesicle lumen	The volume enclosed by the membrane of the multivesicular body internal vesicle.	got7fsn_ti							pr	2013-07-08T20:38:36Z						cellular_component											owl:Class	
GO:0031983	biolink:NamedThing	vesicle lumen	The volume enclosed by the membrane or protein that forms a vesicle.	got7fsn_ti												NIF_Subcellular:sao797538226		cellular_component											owl:Class	
GO:0016423	biolink:NamedThing	tRNA (guanine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.	got7fsn_ti	tRNA (guanosine) methyltransferase activity										GO:0016424			molecular_function											owl:Class	
GO:0008175	biolink:NamedThing	tRNA methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.	got7fsn_ti												Reactome:R-HSA-6786500|Reactome:R-HSA-6786567|Reactome:R-HSA-6783473|Reactome:R-HSA-6782881|Reactome:R-HSA-6782879|Reactome:R-HSA-6782890		molecular_function											owl:Class	
GO:0048629	biolink:NamedThing	trichome patterning	The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes.	got7fsn_ti	trichome spacing|trichome pattern biosynthesis|trichome pattern formation|trichome distribution|trichome pattern specification													biological_process											owl:Class	
GO:0045168	biolink:NamedThing	cell-cell signaling involved in cell fate commitment	Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.	got7fsn_ti	cell-cell signaling during in cell fate commitment|cell fate commitment, cell-cell signaling|cell fate commitment, cell-cell signalling|cell-cell signaling resulting in cell fate commitment|cell-cell signalling during cell fate commitment|cell-cell signalling involved in cell fate specification|cell-cell signalling resulting in cell fate commitment													biological_process											owl:Class	
GO:0003218	biolink:NamedThing	cardiac left ventricle formation	The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.	got7fsn_ti							dph	2009-10-13T09:54:33Z						biological_process											owl:Class	
GO:0008454	biolink:NamedThing	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.	got7fsn_ti	N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity|uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|beta-acetylglucosaminyltransferase IV activity|alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase IV activity|UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV|GnTIV activity											Reactome:R-HSA-975903|EC:2.4.1.145|MetaCyc:2.4.1.145-RXN|Reactome:R-HSA-9696980|RHEA:16057		molecular_function											owl:Class	
GO:0018162	biolink:NamedThing	peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine	The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine.	got7fsn_ti												RESID:AA0253		biological_process											owl:Class	
GO:0071836	biolink:NamedThing	nectar secretion	The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins.	got7fsn_ti	nectar production						mah	2010-09-09T01:06:04Z						biological_process											owl:Class	
GO:0046903	biolink:NamedThing	secretion	The controlled release of a substance by a cell or a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0018495	biolink:NamedThing	2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0192		molecular_function											owl:Class	
GO:0051801	biolink:NamedThing	cytolysis in other organism involved in symbiotic interaction	The killing by an organism of a cell in a second organism by means of the rupture of cell membranes and the loss of cytoplasm, where the two organisms are in a symbiotic interaction.	got7fsn_ti	cytolysis of cells in other organism during symbiotic interaction|cytolysis of cells in other organism involved in symbiotic interaction													biological_process											owl:Class	
GO:0051715	biolink:NamedThing	cytolysis in other organism	The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm.	got7fsn_ti	cytolysis of cells of another organism|cytolysis of cells of another, non-host, organism|cytolysis of cells of competing organism										GO:0001901			biological_process											owl:Class	
GO:0047598	biolink:NamedThing	7-dehydrocholesterol reductase activity	Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+.	got7fsn_ti	sterol delta7-reductase activity|cholesterol:NADP+ delta7-oxidoreductase activity|sterol Delta(7)-reductase activity|7-DHC reductase activity											Reactome:R-HSA-6807055|Reactome:R-HSA-196402|RHEA:23984|EC:1.3.1.21|MetaCyc:RXN66-323		molecular_function											owl:Class	
GO:0004540	biolink:NamedThing	ribonuclease activity	Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0030195	biolink:NamedThing	negative regulation of blood coagulation	Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.	got7fsn_ti	down-regulation of blood coagulation|inhibition of blood coagulation|down regulation of blood coagulation|downregulation of blood coagulation													biological_process											owl:Class	
GO:0050819	biolink:NamedThing	negative regulation of coagulation	Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.	got7fsn_ti	downregulation of coagulation|anticoagulant activity|down regulation of coagulation|inhibition of coagulation|negative regulation of clotting|down-regulation of coagulation													biological_process											owl:Class	
GO:0043414	biolink:NamedThing	macromolecule methylation	The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.	got7fsn_ti														biological_process											owl:Class	
GO:0043412	biolink:NamedThing	macromolecule modification	The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.	got7fsn_ti														biological_process											owl:Class	
GO:0002252	biolink:NamedThing	immune effector process	Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18737												biological_process											owl:Class	
GO:0019128	biolink:NamedThing	peptidyl-tryptophan racemization	The racemization of peptidyl-tryptophan.	got7fsn_ti											GO:0018092|GO:0018374	RESID:AA0198		biological_process											owl:Class	
GO:0018085	biolink:NamedThing	peptidyl-L-amino acid racemization	The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid.	got7fsn_ti														biological_process											owl:Class	
GO:0004317	biolink:NamedThing	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O.	got7fsn_ti	3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity|beta-hydroxypalmityl-ACP dehydrase activity|D-3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity|(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase (hexadec-2-enoyl-acyl-carrier protein-forming)|beta-hydroxypalmitoyl thioester dehydratase activity|(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase activity|3-hydroxypalmitoyl-ACP dehydratase activity|3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activity|D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity|beta-hydroxypalmitoyl-acyl carrier protein dehydrase activity|(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase activity											RHEA:41908|KEGG_REACTION:R04462|EC:4.2.1.59|MetaCyc:4.2.1.61-RXN		molecular_function											owl:Class	
GO:0019171	biolink:NamedThing	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: a (3R)-3-hydroxyacyl-[acyl-carrier protein] = H2O + a trans-delta2-enoyl-acyl-[acyl-carrier protein].	got7fsn_ti	3-hydroxyacyl-[acyl-carrier protein] dehydratase activity|3-hydroxyacyl-ACP dehydratase activity											RHEA:13097|EC:4.2.1.59|MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN		molecular_function											owl:Class	
GO:0044301	biolink:NamedThing	climbing fiber	The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber.	got7fsn_ti	climbing fibre						jl	2010-02-05T11:20:56Z				NIF_Subcellular:nlx_subcell_20090203		cellular_component											owl:Class	
GO:0030424	biolink:NamedThing	axon	The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.	got7fsn_ti												Wikipedia:Axon|NIF_Subcellular:sao1770195789		cellular_component											owl:Class	
GO:1903041	biolink:NamedThing	regulation of chondrocyte hypertrophy	Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy.	got7fsn_ti							mr	2014-05-20T21:23:13Z						biological_process											owl:Class	
GO:0030433	biolink:NamedThing	ubiquitin-dependent ERAD pathway	The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.	got7fsn_ti	endoplasmic reticulum-associated ubiqutin-dependent protein catabolism|ER-associated ubiquitin-dependent protein catabolism|ERAD|ER-associated ubiquitin-dependent protein breakdown|ER-associated ubiquitin-dependent protein degradation|ER-associated ubiquitin-dependent protein catabolic process|ubiquitin-dependent proteasomal protein catabolism of ER proteins|endoplasmic reticulum-associated ubiquitin-dependent protein catabolic process				See also the biological process terms 'ERAD pathway ; GO:0036503', 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.									biological_process											owl:Class	
GO:0043161	biolink:NamedThing	proteasome-mediated ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	got7fsn_ti	proteasome pathway|proteasomal ubiquitin-dependent protein breakdown|proteasomal processing|proteasomal ubiquitin-dependent protein catabolism|proteasomal ubiquitin-dependent protein catabolic process|proteasomal ubiquitin-dependent protein degradation|proteasomal pathway													biological_process											owl:Class	
GO:0000150	biolink:NamedThing	DNA strand exchange activity	Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.	got7fsn_ti	strand transferase|strand exchange activity|recombinase activity|RecA-family recombinase activity	https://github.com/geneontology/go-ontology/issues/20964			Note that this term represents activities that do not break or form phosphodiester bonds, and is therefore not a parent of 'site-specific recombinase activity ; GO:0009009'.							Reactome:R-HSA-912458		molecular_function											owl:Class	
GO:0009941	biolink:NamedThing	chloroplast envelope	The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	got7fsn_ti														cellular_component											owl:Class	
GO:0009526	biolink:NamedThing	plastid envelope	The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	got7fsn_ti														cellular_component											owl:Class	
GO:0021828	biolink:NamedThing	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus.	got7fsn_ti	gonadotropin-releasing hormone neuronal migration to the hypothalamus										GO:0021857			biological_process											owl:Class	
GO:0042321	biolink:NamedThing	negative regulation of circadian sleep/wake cycle, sleep	Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.	got7fsn_ti	negative regulation of sleep|inhibition of circadian sleep/wake cycle, sleep|downregulation of circadian sleep/wake cycle, sleep|down-regulation of circadian sleep/wake cycle, sleep|down regulation of circadian sleep/wake cycle, sleep													biological_process											owl:Class	
GO:0045187	biolink:NamedThing	regulation of circadian sleep/wake cycle, sleep	Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.	got7fsn_ti	regulation of sleep													biological_process											owl:Class	
GO:0061928	biolink:NamedThing	glutathione specific gamma-glutamylcyclotransferase activity	Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine.	got7fsn_ti							dph	2017-08-29T14:55:30Z				EC:4.3.2.7|RHEA:47724		molecular_function											owl:Class	
GO:0032586	biolink:NamedThing	protein storage vacuole membrane	The lipid bilayer surrounding a protein storage vacuole.	got7fsn_ti														cellular_component											owl:Class	
GO:0009705	biolink:NamedThing	plant-type vacuole membrane	The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.	got7fsn_ti	membrane of vacuole with cell cycle-independent morphology|tonoplast|vacuolar membrane													cellular_component											owl:Class	
GO:1901568	biolink:NamedThing	fatty acid derivative metabolic process	The chemical reactions and pathways involving fatty acid derivative.	got7fsn_ti	fatty acid derivative metabolism						pr	2012-11-04T17:13:36Z						biological_process											owl:Class	
GO:1902406	biolink:NamedThing	mitotic actomyosin contractile ring maintenance	Any actomyosin contractile ring maintenance that is involved in mitotic cell cycle.	got7fsn_ti	cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle|contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle						jl	2013-09-12T12:28:14Z						biological_process											owl:Class	
GO:0102663	biolink:NamedThing	gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A34 + 2-oxoglutarate + O2 <=> H+ + gibberellin A34-catabolite + succinate + carbon dioxide + H2O.	got7fsn_ti												MetaCyc:RXN-292		molecular_function											owl:Class	
GO:0047307	biolink:NamedThing	diaminobutyrate-pyruvate transaminase activity	Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde.	got7fsn_ti	diaminobutyrate--pyruvate aminotransferase activity|diaminobutyrate-pyruvate aminotransferase activity|L-2,4-diaminobutanoate:pyruvate aminotransferase activity|L-diaminobutyric acid transaminase activity											KEGG_REACTION:R02293|RHEA:12380|EC:2.6.1.46|MetaCyc:2.6.1.46-RXN		molecular_function											owl:Class	
GO:0047673	biolink:NamedThing	anthranilate N-malonyltransferase activity	Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA.	got7fsn_ti	malonyl-CoA:anthranilate N-malonyltransferase activity											KEGG_REACTION:R00989|RHEA:17557|MetaCyc:ANTHRANILATE-N-MALONYLTRANSFERASE-RXN|EC:2.3.1.113		molecular_function											owl:Class	
GO:0050735	biolink:NamedThing	N-malonyltransferase activity	Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0021710	biolink:NamedThing	cerebellar stellate cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0021533	biolink:NamedThing	cell differentiation in hindbrain	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0008467	biolink:NamedThing	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.	got7fsn_ti	heparin-glucosamine 3-O-sulphotransferase activity|isoform/isozyme 1 (3-OST-1, HS3ST1)|heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity|heparin-glucosamine 3-O-sulfotransferase activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase|3-OST-1 activity|glucosaminyl 3-O-sulfotransferase activity|3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity											Reactome:R-HSA-2076611|MetaCyc:2.8.2.23-RXN|EC:2.8.2.23|Reactome:R-HSA-2076383		molecular_function											owl:Class	
GO:0015398	biolink:NamedThing	high-affinity secondary active ammonium transmembrane transporter activity	Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity secondary active ammonium transmembrane transporter activity													molecular_function											owl:Class	
GO:0004635	biolink:NamedThing	phosphoribosyl-AMP cyclohydrolase activity	Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H(2)O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide.	got7fsn_ti	PRAMP-cyclohydrolase activity|phosphoribosyladenosine monophosphate cyclohydrolase activity|1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity											KEGG_REACTION:R04037|RHEA:20049|EC:3.5.4.19|MetaCyc:HISTCYCLOHYD-RXN		molecular_function											owl:Class	
GO:0019238	biolink:NamedThing	cyclohydrolase activity	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring.	got7fsn_ti														molecular_function											owl:Class	
GO:0050982	biolink:NamedThing	detection of mechanical stimulus	The series of events by which a mechanical stimulus is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0018592	biolink:NamedThing	4-nitrocatechol 4-monooxygenase activity	Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol.	got7fsn_ti												UM-BBD_reactionID:r0231|EC:1.14.13.166		molecular_function											owl:Class	
GO:0070626	biolink:NamedThing	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.	got7fsn_ti	adenylosuccinate lyase activity|adenylosuccinase activity|succino AMP-lyase activity						mah	2009-05-01T04:13:49Z				EC:4.3.2.2|KEGG_REACTION:R04559|MetaCyc:AICARSYN-RXN|RHEA:23920		molecular_function											owl:Class	
GO:0042719	biolink:NamedThing	mitochondrial intermembrane space protein transporter complex	Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.	got7fsn_ti	Tim9-Tim10 complex													cellular_component											owl:Class	
GO:0030348	biolink:NamedThing	syntaxin-3 binding	Binding to a syntaxin-3 SNAP receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0019905	biolink:NamedThing	syntaxin binding	Binding to a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.	got7fsn_ti	syntaxin-5 binding|syntaxin-2 binding|syntaxin-6 binding|syntaxin-13 binding										GO:0030349|GO:0030347|GO:0051535|GO:0050430			molecular_function											owl:Class	
GO:0098921	biolink:NamedThing	retrograde trans-synaptic signaling by endocannabinoid	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an  endocannabinoid ligand.	got7fsn_ti														biological_process											owl:Class	
GO:0060617	biolink:NamedThing	positive regulation of mammary placode formation by mesenchymal-epithelial signaling	Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.	got7fsn_ti	positive regulation of mammary placode formation by mesenchymal-epithelial signalling						dph	2009-05-18T09:16:07Z						biological_process											owl:Class	
GO:0060638	biolink:NamedThing	mesenchymal-epithelial cell signaling	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted.	got7fsn_ti	mesenchymal-epithelial cell signalling						dph	2009-05-19T03:59:05Z						biological_process											owl:Class	
GO:1900126	biolink:NamedThing	negative regulation of hyaluronan biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process.	got7fsn_ti	downregulation of hyaluronan anabolism|negative regulation of hyaluronan anabolism|inhibition of hyaluronan biosynthetic process|down-regulation of hyaluronan biosynthetic process|down-regulation of hyaluronan anabolism|down regulation of hyaluronan anabolism|negative regulation of hyaluronan synthesis|down regulation of hyaluronan synthesis|downregulation of hyaluronan biosynthesis|inhibition of hyaluronan anabolism|inhibition of hyaluronan formation|down regulation of hyaluronan formation|down-regulation of hyaluronan biosynthesis|inhibition of hyaluronan synthesis|downregulation of hyaluronan formation|negative regulation of hyaluronan formation|down-regulation of hyaluronan synthesis|inhibition of hyaluronan biosynthesis|down regulation of hyaluronan biosynthetic process|negative regulation of hyaluronan biosynthesis|downregulation of hyaluronan synthesis|down regulation of hyaluronan biosynthesis|downregulation of hyaluronan biosynthetic process|down-regulation of hyaluronan formation						yaf	2012-02-23T01:09:29Z						biological_process											owl:Class	
GO:0045912	biolink:NamedThing	negative regulation of carbohydrate metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.	got7fsn_ti	inhibition of carbohydrate metabolic process|down-regulation of carbohydrate metabolic process|down regulation of carbohydrate metabolic process|negative regulation of carbohydrate metabolism|downregulation of carbohydrate metabolic process													biological_process											owl:Class	
GO:0103002	biolink:NamedThing	16-hydroxypalmitate dehydrogenase activity	Catalysis of the reaction: 16-hydroxypalmitate + NADP <=> H+ + 16-oxo-palmitate + NADPH.	got7fsn_ti												MetaCyc:RXN-9802		molecular_function											owl:Class	
GO:0050360	biolink:NamedThing	tryptophan 2'-dioxygenase activity	Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3.	got7fsn_ti	tryptophan side chain oxidase activity|tryptophan side chain oxidase II|tryptophan side chain oxidase type I|TSO I|tryptophan side-chain oxidase activity|L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving)|indole-3-alkane alpha-hydroxylase activity|TSO activity|indolyl-3-alkan alpha-hydroxylase activity|tryptophan side-chain alpha,beta-oxidase activity|TSO II											EC:1.13.99.3|RHEA:22620|MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN		molecular_function											owl:Class	
GO:0006523	biolink:NamedThing	alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.	got7fsn_ti	alanine anabolism|alanine biosynthesis|alanine synthesis|alanine formation													biological_process											owl:Class	
GO:0009079	biolink:NamedThing	pyruvate family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine.	got7fsn_ti	pyruvate family amino acid synthesis|pyruvate family amino acid formation|pyruvate family amino acid anabolism|pyruvate family amino acid biosynthesis													biological_process											owl:Class	
GO:0043236	biolink:NamedThing	laminin binding	Binding to a laminin, a major glycoprotein constituent of the basement membrane of cells.	got7fsn_ti	laminin-4 binding|laminin-2 binding										GO:0043238|GO:0043239			molecular_function											owl:Class	
GO:0104004	biolink:NamedThing	cellular response to environmental stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.	got7fsn_ti							dos	2017-02-17T16:02:42Z						biological_process											owl:Class	
GO:0051716	biolink:NamedThing	cellular response to stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0031493	biolink:NamedThing	nucleosomal histone binding	Binding to a histone that is assembled into a nucleosome.	got7fsn_ti														molecular_function											owl:Class	
GO:0031491	biolink:NamedThing	nucleosome binding	Binding to a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.	got7fsn_ti														molecular_function											owl:Class	
GO:0050911	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of smell	The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal.	got7fsn_ti	perception of smell, detection of chemical stimulus|perception of smell, sensory transduction of chemical stimulus|sensory detection of smell|sensory transduction of scent|sensory transduction of smell|sensory transduction of chemical stimulus during perception of smell|perception of smell, sensory detection of chemical stimulus|sensory detection of scent|sensory detection of chemical stimulus during perception of smell													biological_process											owl:Class	
GO:0050907	biolink:NamedThing	detection of chemical stimulus involved in sensory perception	The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.	got7fsn_ti	sensory transduction of chemical stimulus during sensory perception|sensory detection of chemical stimulus|sensory detection of chemical stimulus during sensory perception|sensory perception, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus|sensory perception, sensory detection of chemical stimulus													biological_process											owl:Class	
GO:0051224	biolink:NamedThing	negative regulation of protein transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	down-regulation of protein transport|down regulation of protein transport|downregulation of protein transport|inhibition of protein transport													biological_process											owl:Class	
GO:0033058	biolink:NamedThing	directional locomotion	Self-propelled movement of a cell or organism from one location to another along an axis.	got7fsn_ti														biological_process											owl:Class	
GO:0006789	biolink:NamedThing	bilirubin conjugation	The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin.	got7fsn_ti														biological_process											owl:Class	
GO:0006787	biolink:NamedThing	porphyrin-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.	got7fsn_ti	porphyrin catabolism|porphyrin catabolic process|porphyrin breakdown|porphyrin degradation													biological_process											owl:Class	
GO:0042337	biolink:NamedThing	cuticle development involved in chitin-based cuticle molting cycle	The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster.	got7fsn_ti	cuticle anabolism during molting|cuticle biosynthetic process during molting|cuticle formation during molting|cuticle synthesis during molting|chitin-based cuticle development during molting													biological_process											owl:Class	
GO:0040003	biolink:NamedThing	chitin-based cuticle development	Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	chitin-based cuticle synthesis|chitin-based cuticle formation|chitin-based cuticle biosynthetic process|chitin-based cuticle anabolism													biological_process											owl:Class	
GO:0120112	biolink:NamedThing	UDP-glucose transmembrane transport into endoplasmic reticulum	The directed movement of UDP-glucose from cytosol to endoplasmic reticulum.	got7fsn_ti							krc	2017-11-02T15:56:51Z						biological_process											owl:Class	
GO:0015786	biolink:NamedThing	UDP-glucose transmembrane transport	The process in which UDP-glucose is transported across a membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0050952	biolink:NamedThing	sensory perception of electrical stimulus	The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti														biological_process											owl:Class	
GO:0031598	biolink:NamedThing	nuclear proteasome regulatory particle	The regulatory subcomplex of a proteasome located in the nucleus of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0043678	biolink:NamedThing	intine	The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm.	got7fsn_ti					Note that the intine is not acetolysis resistant and is therefore absent in conventionally prepared palynological material.									cellular_component											owl:Class	
GO:0032869	biolink:NamedThing	cellular response to insulin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	got7fsn_ti														biological_process											owl:Class	
GO:0032868	biolink:NamedThing	response to insulin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	got7fsn_ti	response to insulin stimulus													biological_process											owl:Class	
GO:0090684	biolink:NamedThing	contact chemoreceptor activity	A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception.	got7fsn_ti	contact chemosensation receptor activity						tb	2016-05-20T15:53:01Z						molecular_function											owl:Class	
GO:0008527	biolink:NamedThing	taste receptor activity	Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste.	got7fsn_ti	gustatory receptor													molecular_function											owl:Class	
GO:0052867	biolink:NamedThing	phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity	Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate.	got7fsn_ti	triphosphoinositide phosphatase activity|phosphatidylinositol 1,4,5-trisphosphate phosphatase activity|triphosphoinositide phosphomonoesterase activity|PtdIns(1,4,5)P(3) phosphatase activity|phosphatidyl-myo-inositol-1,4,5-trisphosphate phosphatase activity|PtdIns(1,4,5)P3 phosphatase activity|phosphatidylinositol-trisphosphatase activity							2012-01-11T12:07:50Z						molecular_function											owl:Class	
GO:0034595	biolink:NamedThing	phosphatidylinositol phosphate 5-phosphatase activity	Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate.	got7fsn_ti	polyphosphoinositol lipid 5-phosphatase activity|phosphoinositide 5-phosphatase activity													molecular_function											owl:Class	
GO:0045058	biolink:NamedThing	T cell selection	The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.	got7fsn_ti	T-lymphocyte selection|T lymphocyte selection|T-cell selection											Wikipedia:Thymocyte		biological_process											owl:Class	
GO:0002376	biolink:NamedThing	immune system process	Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.	got7fsn_ti					Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501).							Wikipedia:Immune_system		biological_process											owl:Class	
GO:0001656	biolink:NamedThing	metanephros development	The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti														biological_process											owl:Class	
GO:0001822	biolink:NamedThing	kidney development	The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.	got7fsn_ti	nephrogenesis											Wikipedia:Kidney_development		biological_process											owl:Class	
GO:0019453	biolink:NamedThing	L-cysteine catabolic process via cystine	The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine.	got7fsn_ti	L-cysteine breakdown via cystine|L-cysteine degradation via cystine													biological_process											owl:Class	
GO:0019448	biolink:NamedThing	L-cysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.	got7fsn_ti	L-cysteine degradation|L-cysteine breakdown|L-cysteine catabolism													biological_process											owl:Class	
GO:0019390	biolink:NamedThing	glucuronoside biosynthetic process	The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.	got7fsn_ti	glucuronoside biosynthesis|glucuronide biosynthesis|glucuronoside formation|glucuronoside synthesis|glucuronoside anabolism|glucuronide biosynthetic process													biological_process											owl:Class	
GO:0106032	biolink:NamedThing	snRNA pseudouridine synthase activity	Catalysis of the reaction: an snRNA uridine = an snRNA pseudouridine. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.	got7fsn_ti							hjd	2017-06-28T17:44:20Z						molecular_function											owl:Class	
GO:0140098	biolink:NamedThing	catalytic activity, acting on RNA	Catalytic activity that acts to modify RNA, driven by ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21612|https://github.com/geneontology/go-ontology/issues/14225					pg	2017-09-14T12:05:21Z						molecular_function											owl:Class	
GO:0055127	biolink:NamedThing	vibrational conductance of sound to the inner ear	The transmission of vibrations via ossicles to the inner ear.	got7fsn_ti							jid	2009-10-13T10:59:39Z						biological_process											owl:Class	
GO:0070231	biolink:NamedThing	T cell apoptotic process	Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.	got7fsn_ti	T cell apoptosis|programmed cell death of T cells by apoptosis|T-lymphocyte apoptosis|T lymphocyte apoptosis|T-cell apoptosis													biological_process											owl:Class	
GO:0043271	biolink:NamedThing	negative regulation of ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	down-regulation of ion transport|down regulation of ion transport|inhibition of ion transport|downregulation of ion transport													biological_process											owl:Class	
GO:0043269	biolink:NamedThing	regulation of ion transport	Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0030059	biolink:NamedThing	aralkylamine dehydrogenase (azurin) activity	Catalysis of the reaction: an aralkylamine + H2O + 2 oxidized [azurin] = an aromatic aldehyde + 2 H+ + NH4+ + 2 reduced [azurin].	got7fsn_ti	aralkylamine:(azurin) oxidoreductase (deaminating) activity|aromatic amine dehydrogenase (azurin) activity											RHEA:47796|EC:1.4.9.2|MetaCyc:ARALKYLAMINE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0042915	biolink:NamedThing	group A colicin transport	The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0042914	biolink:NamedThing	colicin transport	The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.	got7fsn_ti														biological_process											owl:Class	
GO:1990490	biolink:NamedThing	archaeal proton-transporting A-type ATPase complex	A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea.	got7fsn_ti	archaeal A-type ATPase protein complex|A-type ATPase protein complex						tt	2014-09-20T19:13:55Z						cellular_component											owl:Class	
GO:0016469	biolink:NamedThing	proton-transporting two-sector ATPase complex	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.	got7fsn_ti	vacuolar hydrogen-transporting ATPase|hydrogen-transporting two-sector ATPase complex													cellular_component											owl:Class	
GO:0010136	biolink:NamedThing	ureide catabolic process	The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium.	got7fsn_ti	ureide breakdown|ureide degradation|ureide catabolism											MetaCyc:URDEGR-PWY		biological_process											owl:Class	
GO:0009830	biolink:NamedThing	cell wall modification involved in abscission	A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission.	got7fsn_ti	cell wall modification during abscission													biological_process											owl:Class	
GO:0050463	biolink:NamedThing	nitrate reductase [NAD(P)H] activity	Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+.	got7fsn_ti	nitrite:NAD(P)+ oxidoreductase activity|nitrate reductase NAD(P)H activity|assimilatory nitrate reductase activity|nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity|nitrate reductase [NAD(P)H2]|NAD(P)H:nitrate oxidoreductase activity|assimilatory NAD(P)H-nitrate reductase activity|NAD(P)H2:nitrate oxidoreductase activity|NAD(P)H-nitrate reductase activity|NAD(P)H bispecific nitrate reductase activity											EC:1.7.1.2		molecular_function											owl:Class	
GO:0008940	biolink:NamedThing	nitrate reductase activity	Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor.	got7fsn_ti	nitrite:(acceptor) oxidoreductase|nitrate reductase (acceptor)|respiratory nitrate reductase activity|nitrite:acceptor oxidoreductase											RHEA:21068|MetaCyc:NITRATREDUCT-RXN|EC:1.7.99.4		molecular_function											owl:Class	
GO:0045763	biolink:NamedThing	negative regulation of cellular amino acid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.	got7fsn_ti	inhibition of amino acid metabolic process|down-regulation of amino acid metabolic process|negative regulation of amino acid metabolism|down regulation of amino acid metabolic process|downregulation of amino acid metabolic process													biological_process											owl:Class	
GO:0033239	biolink:NamedThing	negative regulation of cellular amine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.	got7fsn_ti	negative regulation of amine metabolism													biological_process											owl:Class	
GO:0030836	biolink:NamedThing	positive regulation of actin filament depolymerization	Any process that activates or increases the frequency, rate or extent of actin depolymerization.	got7fsn_ti	actin filament destabilization|positive regulation of actin depolymerization|up-regulation of actin filament depolymerization|upregulation of actin filament depolymerization|positive regulation of actin polymerization and/or depolymerization|activation of actin filament depolymerization|up regulation of actin filament depolymerization|stimulation of actin filament depolymerization				Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin polymerization ; GO:0030838').						GO:0030045			biological_process											owl:Class	
GO:0051495	biolink:NamedThing	positive regulation of cytoskeleton organization	Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.	got7fsn_ti	up-regulation of cytoskeleton organization|positive regulation of cytoskeleton organisation|activation of cytoskeleton organization|stimulation of cytoskeleton organization|up regulation of cytoskeleton organization|upregulation of cytoskeleton organization|positive regulation of cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:0075528	biolink:NamedThing	modulation by virus of host immune response	The process in which a virus effects a change in the host immune response.	got7fsn_ti	regulation by virus of host immune system process						jl	2011-08-04T02:47:57Z						biological_process											owl:Class	
GO:0004769	biolink:NamedThing	steroid delta-isomerase activity	Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid.	got7fsn_ti	hydroxysteroid isomerase activity|delta(5)-3-ketosteroid isomerase activity|3-oxosteroid delta5-delta4-isomerase activity|delta5-3-keto steroid isomerase activity|delta5-3-oxosteroid isomerase activity|delta5(or delta4)-3-keto steroid isomerase activity|delta5-3-ketosteroid isomerase activity|steroid D-isomerase activity|delta5-ketosteroid isomerase activity|delta(5)-3-oxosteroid isomerase activity|steroid isomerase activity|delta(5)-steroid isomerase activity|delta(5)-3-keto steroid isomerase activity|3-oxosteroid isomerase activity|delta5-steroid isomerase activity											Reactome:R-HSA-193052|Reactome:R-HSA-6807052|Reactome:R-HSA-193961|Reactome:R-HSA-195690|RHEA:14709|EC:5.3.3.1|MetaCyc:STEROID-DELTA-ISOMERASE-RXN|Reactome:R-HSA-193073		molecular_function											owl:Class	
GO:0033821	biolink:NamedThing	DNA beta-glucosyltransferase activity	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.	got7fsn_ti	uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase activity|UDP glucose-DNA beta-glucosyltransferase activity|T4-beta-glucosyl transferase activity|T4-HMC-beta-glucosyl transferase activity|UDPglucose:DNA beta-D-glucosyltransferase activity|T4 phage beta-glucosyltransferase activity|UDP-glucose:DNA beta-D-glucosyltransferase activity											MetaCyc:2.4.1.27-RXN|EC:2.4.1.27		molecular_function											owl:Class	
GO:0019778	biolink:NamedThing	Atg12 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti	APG12 activating enzyme activity													molecular_function											owl:Class	
GO:0008641	biolink:NamedThing	ubiquitin-like modifier activating enzyme activity	Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti	small protein activating enzyme activity	https://github.com/geneontology/go-ontology/issues/14208									GO:0008642			molecular_function											owl:Class	
GO:0004501	biolink:NamedThing	ecdysone 20-monooxygenase activity	Catalysis of the reaction: AH(2) + Ecdysone + O(2) = 20-hydroxyecdysone + A + H(2)O.	got7fsn_ti	ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating)|ecdysone 20-hydroxylase activity|ecdysone modification|alpha-ecdysone C-20 hydroxylase activity											EC:1.14.99.22|KEGG_REACTION:R02374|MetaCyc:ECDYSONE-20-MONOOXYGENASE-RXN|RHEA:14021		molecular_function											owl:Class	
GO:0001532	biolink:NamedThing	interleukin-21 receptor activity	Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-21R|IL-21 receptor activity													molecular_function											owl:Class	
GO:0030868	biolink:NamedThing	smooth endoplasmic reticulum membrane	The lipid bilayer surrounding the smooth endoplasmic reticulum.	got7fsn_ti	SER membrane|smooth ER membrane											NIF_Subcellular:sao1596955044		cellular_component											owl:Class	
GO:0005789	biolink:NamedThing	endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.	got7fsn_ti	ER membrane													cellular_component											owl:Class	
GO:0048457	biolink:NamedThing	floral whorl morphogenesis	The process in which the anatomical structures of the floral whorl are generated and organized.	got7fsn_ti											GO:0048414			biological_process											owl:Class	
GO:1990904	biolink:NamedThing	ribonucleoprotein complex	A macromolecular complex that contains both RNA and protein molecules.	got7fsn_ti	protein-RNA complex|intracellular ribonucleoprotein complex|ribonucleoprotein complex|RNA-protein complex|RNP|extracellular ribonucleoprotein complex						pr	2015-11-19T12:26:37Z			GO:0030529|GO:1990903	Wikipedia:Ribonucleoprotein		cellular_component											owl:Class	
GO:0061656	biolink:NamedThing	SUMO conjugating enzyme activity	Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2						dph	2014-11-06T13:33:20Z						molecular_function											owl:Class	
GO:0061650	biolink:NamedThing	ubiquitin-like protein conjugating enzyme activity	Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2|small conjugating protein conjugating enzyme activity						dph	2014-11-06T13:15:27Z						molecular_function											owl:Class	
GO:0007147	biolink:NamedThing	female meiosis II	The cell cycle process in which the second meiotic division occurs in the female germline.	got7fsn_ti	female meiosis II nuclear division													biological_process											owl:Class	
GO:0007143	biolink:NamedThing	female meiotic nuclear division	A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.	got7fsn_ti	female meiosis|female meiotic division				Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'.									biological_process											owl:Class	
GO:0018559	biolink:NamedThing	1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity	Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.	got7fsn_ti	1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethylene 1,2-dioxygenase activity											UM-BBD_reactionID:r0442|EC:1.13.11.-		molecular_function											owl:Class	
GO:0052872	biolink:NamedThing	tocotrienol omega-hydroxylase activity	Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O .	got7fsn_ti	tocotrienol 13-hydroxylase activity						ai	2012-01-30T03:07:27Z				EC:1.14.13.-		molecular_function											owl:Class	
GO:0071142	biolink:NamedThing	homomeric SMAD protein complex	A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive.	got7fsn_ti	SMAD3 homotrimer complex|SMAD1 protein complex|SMAD2 homotrimer complex|SMAD2 protein complex|SMAD1 homotrimer complex|SMAD3 protein complex						mah	2009-11-16T02:41:19Z			GO:0071143			cellular_component											owl:Class	
GO:0071141	biolink:NamedThing	SMAD protein complex	A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.	got7fsn_ti	SMAD complex						mah	2009-11-16T02:28:59Z						cellular_component											owl:Class	
GO:0102982	biolink:NamedThing	UDP-3-dehydro-alpha-D-glucose dehydrogenase activity	Catalysis of the reaction: UDP-alpha-D-glucose + NAD <=> H+ + UDP-3-keto-alpha-D-glucose + NADH.	got7fsn_ti												RHEA:35755|MetaCyc:RXN-9578		molecular_function											owl:Class	
GO:0021614	biolink:NamedThing	glossopharyngeal nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	got7fsn_ti	CN IX maturation													biological_process											owl:Class	
GO:0052338	biolink:NamedThing	disruption by host of symbiont cell wall	The chemical reactions and pathways performed by an organism resulting in the breakdown of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	degradation of symbiont cell wall by organism|disassembly by host of symbiont cell wall|catabolism of symbiont cell wall by organism													biological_process											owl:Class	
GO:0052339	biolink:NamedThing	disruption by organism of cell wall of other organism involved in symbiotic interaction	The chemical reactions and pathways performed by an organism resulting in the breakdown of the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	disassembly by organism of cell wall of other organism during symbiotic interaction													biological_process											owl:Class	
GO:0120098	biolink:NamedThing	procentriole	A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells.	got7fsn_ti							krc	2017-09-28T21:22:56Z						cellular_component											owl:Class	
GO:0031327	biolink:NamedThing	negative regulation of cellular biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.	got7fsn_ti	downregulation of cellular biosynthetic process|negative regulation of cellular biosynthesis|negative regulation of cellular anabolism|negative regulation of cellular synthesis|negative regulation of cellular formation|down-regulation of cellular biosynthetic process|inhibition of cellular biosynthetic process|down regulation of cellular biosynthetic process													biological_process											owl:Class	
GO:0009651	biolink:NamedThing	response to salt stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti	salinity response|response to ionic osmotic stress													biological_process											owl:Class	
GO:0006970	biolink:NamedThing	response to osmotic stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti	osmotic response|osmotic stress response													biological_process											owl:Class	
GO:0032344	biolink:NamedThing	regulation of aldosterone metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.	got7fsn_ti	regulation of aldosterone metabolism													biological_process											owl:Class	
GO:0050212	biolink:NamedThing	progesterone 11-alpha-monooxygenase activity	Catalysis of the reaction: AH(2) + O(2) + progesterone = 11alpha-hydroxyprogesterone + A + H(2)O.	got7fsn_ti	progesterone 11-alpha-hydroxylase activity|progesterone 11alpha-hydroxylase activity|progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating)|progesterone 11a-monooxygenase activity|progesterone 11alpha-monooxygenase activity											EC:1.14.99.14|RHEA:18205|MetaCyc:PROGESTERONE-11-ALPHA-MONOOXYGENASE-RXN|KEGG_REACTION:R02214		molecular_function											owl:Class	
GO:0035742	biolink:NamedThing	activated CD8-positive, alpha-beta T cell proliferation	The expansion of an activated CD8-positive, alpha-beta T cell population by cell division.	got7fsn_ti							bf	2011-03-17T02:19:58Z						biological_process											owl:Class	
GO:0103088	biolink:NamedThing	2-(6'-methylthio)hexylmalate synthase activity	Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA + H2O <=> H+ + 2-(6'-methylthio)hexylmalate + coenzyme A.	got7fsn_ti												MetaCyc:RXNQT-4172		molecular_function											owl:Class	
GO:0009000	biolink:NamedThing	selenocysteine lyase activity	Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor.	got7fsn_ti	selenocysteine beta-lyase activity|selenocysteine reductase activity|L-selenocysteine selenide-lyase (L-alanine-forming)											MetaCyc:SELENOCYSTEINE-LYASE-RXN|EC:4.4.1.16|RHEA:11632|Reactome:R-HSA-2408524		molecular_function											owl:Class	
GO:0047062	biolink:NamedThing	trans-acenaphthene-1,2-diol dehydrogenase activity	Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthene-1,2-dione + 2 H(+) + 2 NADPH.	got7fsn_ti	trans-1,2-acenaphthenediol dehydrogenase activity|(+-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase activity											MetaCyc:1.10.1.1-RXN|RHEA:22184|KEGG_REACTION:R04059|EC:1.10.1.1		molecular_function											owl:Class	
GO:0016680	biolink:NamedThing	oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP.	got7fsn_ti												EC:1.10.1.-		molecular_function											owl:Class	
GO:0032525	biolink:NamedThing	somite rostral/caudal axis specification	The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.	got7fsn_ti	somite rostrocaudal polarity|somite rostrocaudal axis specification													biological_process											owl:Class	
GO:0000578	biolink:NamedThing	embryonic axis specification	The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.	got7fsn_ti	embryonic axis determination													biological_process											owl:Class	
GO:0042930	biolink:NamedThing	enterobactin transport	The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	enterochelin transport													biological_process											owl:Class	
GO:0015891	biolink:NamedThing	siderophore transport	The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	siderophore-iron transport|siderochrome transport|iron-siderochrome transport|iron-siderophore transport										GO:0015892			biological_process											owl:Class	
GO:0030560	biolink:NamedThing	tRNA pseudouridylation guide activity	Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0030558	biolink:NamedThing	RNA pseudouridylation guide activity	Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0050531	biolink:NamedThing	mannosyl-3-phosphoglycerate phosphatase activity	Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate.	got7fsn_ti	alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase activity											EC:3.1.3.70|MetaCyc:3.1.3.70-RXN|KEGG_REACTION:R05790|RHEA:19309		molecular_function											owl:Class	
GO:0070874	biolink:NamedThing	negative regulation of glycogen metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.	got7fsn_ti	negative regulation of glycogen metabolism						mah	2009-08-20T02:50:41Z						biological_process											owl:Class	
GO:0033953	biolink:NamedThing	alpha-agarase activity	Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.	got7fsn_ti	agarose 3-glycanohydrolase activity|agarase A33 activity|agarase activity											EC:3.2.1.158|MetaCyc:3.2.1.158-RXN		molecular_function											owl:Class	
GO:0030586	biolink:NamedThing	[methionine synthase] reductase activity	Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.	got7fsn_ti	methionine synthase reductase activity|5-methyltetrahydrofolate-homocysteine methyltransferase reductase|[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity|methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity|methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)|methionine synthase cob(II)alamin reductase (methylating) activity				Formerly EC:2.1.1.135.							Reactome:R-HSA-3149518|RHEA:23908|EC:1.16.1.8|MetaCyc:2.1.1.135-RXN		molecular_function											owl:Class	
GO:0016723	biolink:NamedThing	oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor	Catalysis of an oxidation-reduction in which the metal ion is reduced and NAD+ or NADP+ acts as an electron acceptor.	got7fsn_ti	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor|oxidoreductase activity, reducing metal ions, NAD or NADP as acceptor	https://github.com/geneontology/go-ontology/issues/20675										Reactome:R-HSA-917811|EC:1.16.1.-		molecular_function											owl:Class	
GO:0008720	biolink:NamedThing	D-lactate dehydrogenase activity	Catalysis of the reaction: (R)-lactate + NAD(+) = H(+) + NADH + pyruvate.	got7fsn_ti	D-lactic acid dehydrogenase activity|D-lactic dehydrogenase activity											MetaCyc:DLACTDEHYDROGNAD-RXN|EC:1.1.1.28|KEGG_REACTION:R00704|RHEA:16369		molecular_function											owl:Class	
GO:0004457	biolink:NamedThing	lactate dehydrogenase activity	Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.	got7fsn_ti														molecular_function											owl:Class	
GO:0007283	biolink:NamedThing	spermatogenesis	The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.	got7fsn_ti	generation of spermatozoa											Wikipedia:Spermatogenesis		biological_process											owl:Class	
GO:0018780	biolink:NamedThing	dichloroacetate halidohydrolase activity	Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate.	got7fsn_ti												UM-BBD_reactionID:r0383		molecular_function											owl:Class	
GO:0031693	biolink:NamedThing	alpha-1D adrenergic receptor binding	Binding to an alpha-1D adrenergic receptor.	got7fsn_ti	alpha-1D adrenergic receptor ligand													molecular_function											owl:Class	
GO:0042566	biolink:NamedThing	hydrogenosome	A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation.	got7fsn_ti												Wikipedia:Hydrogenosome		cellular_component											owl:Class	
GO:0043231	biolink:NamedThing	intracellular membrane-bounded organelle	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.	got7fsn_ti	intracellular membrane-enclosed organelle													cellular_component											owl:Class	
GO:0061366	biolink:NamedThing	behavioral response to chemical pain	Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.	got7fsn_ti							dph	2010-10-21T03:25:01Z						biological_process											owl:Class	
GO:0048266	biolink:NamedThing	behavioral response to pain	Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.	got7fsn_ti	behavioural response to pain													biological_process											owl:Class	
GO:1990895	biolink:NamedThing	regulation of protein localization to cell cortex of cell tip	Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip.	got7fsn_ti							vw	2015-11-04T21:53:15Z						biological_process											owl:Class	
GO:1904776	biolink:NamedThing	regulation of protein localization to cell cortex	Any process that modulates the frequency, rate or extent of protein localization to cell cortex.	got7fsn_ti	regulation of protein localisation to cell cortex				An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.		es	2015-10-29T16:55:01Z						biological_process											owl:Class	
GO:0102913	biolink:NamedThing	3-aminomethylindole N-methyltransferase activity	Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine  = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:52268|MetaCyc:RXN-8686		molecular_function											owl:Class	
GO:0016518	biolink:NamedThing	interleukin-14 receptor activity	Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-14R|IL-14 receptor activity													molecular_function											owl:Class	
GO:0008610	biolink:NamedThing	lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.	got7fsn_ti	lipid formation|lipid biosynthesis|lipid anabolism|lipid synthesis|lipogenesis													biological_process											owl:Class	
GO:0030897	biolink:NamedThing	HOPS complex	A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.	got7fsn_ti														cellular_component											owl:Class	
GO:0010108	biolink:NamedThing	detection of glutamine	The series of events in which a glutamine stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	glutamine detection|glutamine perception|glutamine sensing													biological_process											owl:Class	
GO:0009593	biolink:NamedThing	detection of chemical stimulus	The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of chemical substance|detection of chemical substance|chemoreception|chemoperception|perception of chemical stimulus													biological_process											owl:Class	
GO:0102469	biolink:NamedThing	naringenin 2-hydroxylase activity	Catalysis of the reaction: (S)-naringenin + NADPH + O2 <=> 2-hydroxynaringenin + NADP + H2O.	got7fsn_ti												RHEA:57588|MetaCyc:RXN-14069		molecular_function											owl:Class	
GO:0047539	biolink:NamedThing	2-deoxyglucosidase activity	Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol.	got7fsn_ti	2-deoxy-alpha-D-glucosidase activity|2-deoxy-alpha-D-glucoside deoxyglucohydrolase activity|2-deoxy-alpha-glucosidase activity											EC:3.2.1.112|MetaCyc:2-DEOXYGLUCOSIDASE-RXN|RHEA:15317		molecular_function											owl:Class	
GO:0015926	biolink:NamedThing	glucosidase activity	Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0046219	biolink:NamedThing	indolalkylamine biosynthetic process	The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.	got7fsn_ti	indolalkylamine biosynthesis|indolalkylamine formation|indolalkylamine anabolism|indolalkylamine synthesis													biological_process											owl:Class	
GO:0042401	biolink:NamedThing	cellular biogenic amine biosynthetic process	The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.	got7fsn_ti	biogenic amine synthesis|biogenic amine anabolism|biogenic amine biosynthesis|biogenic amine formation													biological_process											owl:Class	
GO:0002018	biolink:NamedThing	renin-angiotensin regulation of aldosterone production	The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.	got7fsn_ti	renin-angiotensin control of aldosterone production													biological_process											owl:Class	
GO:2000858	biolink:NamedThing	regulation of aldosterone secretion	Any process that modulates the frequency, rate or extent of aldosterone secretion.	got7fsn_ti							bf	2011-07-26T08:47:27Z						biological_process											owl:Class	
GO:0036035	biolink:NamedThing	osteoclast development	The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.	got7fsn_ti	osteoclast cell development						bf	2011-11-02T05:20:35Z						biological_process											owl:Class	
GO:2000113	biolink:NamedThing	negative regulation of cellular macromolecule biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process.	got7fsn_ti	negative regulation of cellular macromolecule synthesis|negative regulation of cellular macromolecule formation|negative regulation of cellular macromolecule biosynthesis|negative regulation of cellular biopolymer biosynthetic process|negative regulation of cellular macromolecule anabolism						tb	2010-09-15T08:55:48Z						biological_process											owl:Class	
GO:2000112	biolink:NamedThing	regulation of cellular macromolecule biosynthetic process	Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process.	got7fsn_ti	regulation of cellular macromolecule synthesis|regulation of cellular macromolecule anabolism|regulation of cellular macromolecule biosynthesis|regulation of cellular biopolymer biosynthetic process|regulation of cellular macromolecule formation						tb	2010-09-15T08:55:45Z						biological_process											owl:Class	
GO:0102013	biolink:NamedThing	ATPase-coupled L-glutamate tranmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-glutamate(out) -> ADP + phosphate + L-glutamate(in).	got7fsn_ti	L-glutamate-importing ATPase activity											MetaCyc:ABC-13-RXN		molecular_function											owl:Class	
GO:0015426	biolink:NamedThing	ATPase-coupled polar amino acid-transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).	got7fsn_ti	polar-amino acid-transporting ATPase activity|cystine/diaminopimelate porter activity|polar amino acid-importing ATPase activity|polar-amino acid-importing ATPase activity|polar-amino acid ABC transporter|histidine permease activity|polar-amino-acid-transporting ATPase activity|ATP-dependent polar amino acid-transporter activity|polar amino acid uptake transporter activity|glutamate/aspartate porter activity|histidine/arginine/lysine/ornithine porter activity											RHEA:14673|MetaCyc:3.6.3.21-RXN|EC:7.4.2.1		molecular_function											owl:Class	
GO:0050276	biolink:NamedThing	scyllo-inosamine 4-kinase activity	Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+).	got7fsn_ti	ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase activity|scyllo-inosamine kinase (phosphorylating)|scyllo-inosamine kinase activity|ATP:inosamine phosphotransferase activity											RHEA:18605|EC:2.7.1.65|KEGG_REACTION:R03384|MetaCyc:SCYLLO-INOSAMINE-KINASE-RXN		molecular_function											owl:Class	
GO:0062187	biolink:NamedThing	anandamide 8,9 epoxidase activity	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							dph	2019-11-26T18:51:34Z				RHEA:53140		molecular_function											owl:Class	
GO:0062186	biolink:NamedThing	anandamide epoxidase activity	Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide.	got7fsn_ti	arachidonoylethanolamide epoxidase activity						dph	2019-11-26T18:49:50Z						molecular_function											owl:Class	
GO:0005591	biolink:NamedThing	collagen type VIII trimer	A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets.	got7fsn_ti														cellular_component											owl:Class	
GO:0005598	biolink:NamedThing	short-chain collagen trimer	Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0019876	biolink:NamedThing	nylon catabolic process	The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.	got7fsn_ti	nylon breakdown|nylon degradation|nylon catabolism													biological_process											owl:Class	
GO:0036286	biolink:NamedThing	eisosome filament	A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.	got7fsn_ti	linear eisosome						bf	2012-07-16T10:52:24Z						cellular_component											owl:Class	
GO:0000985	biolink:NamedThing	bacterial-type RNA polymerase core promoter sequence-specific DNA binding	Binding to a DNA sequence that is part of the core promoter of a bacterial gene.	got7fsn_ti	eubacterial-type RNA polymerase core promoter sequence-specific DNA binding						krc	2010-08-10T03:01:38Z						molecular_function											owl:Class	
GO:0050397	biolink:NamedThing	Watasenia-luciferin 2-monooxygenase activity	Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.	got7fsn_ti	Watasenia-luciferin:oxygen 2-oxidoreductase (decarboxylating)|Watasenia-type luciferase activity|luciferase activity											RHEA:18057|EC:1.13.12.8|MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0045289	biolink:NamedThing	luciferin monooxygenase activity	Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation.	got7fsn_ti	luciferase monooxygenase activity|luciferase activity													molecular_function											owl:Class	
GO:0072765	biolink:NamedThing	centromere localization	A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location.	got7fsn_ti	kinetochore localization|kinetochore localisation|establishment and maintenance of kinetochore localization						mah	2012-11-21T13:30:53Z						biological_process											owl:Class	
GO:0051640	biolink:NamedThing	organelle localization	Any process in which an organelle is transported to, and/or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of organelle localization|organelle localisation													biological_process											owl:Class	
GO:0060493	biolink:NamedThing	mesenchymal-endodermal cell signaling involved in lung induction	Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.	got7fsn_ti	mesenchymal-endodermal cell signalling involved in lung induction													biological_process											owl:Class	
GO:0060494	biolink:NamedThing	inductive mesenchymal-endodermal cell signaling	Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell.	got7fsn_ti	inductive mesenchymal-endodermal cell signalling													biological_process											owl:Class	
GO:0044780	biolink:NamedThing	bacterial-type flagellum assembly	The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.	got7fsn_ti	bacterial flagellum assembly						jl	2013-03-27T15:00:43Z						biological_process											owl:Class	
GO:0030031	biolink:NamedThing	cell projection assembly	Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.	got7fsn_ti	formation of a cell surface projection|cell projection biogenesis													biological_process											owl:Class	
GO:0000310	biolink:NamedThing	xanthine phosphoribosyltransferase activity	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate.	got7fsn_ti	5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase activity|Xan phosphoribosyltransferase activity|xanthine-guanine phosphoribosyltransferase activity|XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase activity|xanthylate pyrophosphorylase activity|xanthylic pyrophosphorylase activity|XMP pyrophosphorylase activity|xanthosine 5'-phosphate pyrophosphorylase activity										GO:0009043	RHEA:10800|EC:2.4.2.22|MetaCyc:XANPRIBOSYLTRAN-RXN		molecular_function											owl:Class	
GO:0106130	biolink:NamedThing	purine phosphoribosyltransferase activity	Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.	got7fsn_ti							hjd	2018-06-14T17:38:53Z						molecular_function											owl:Class	
GO:0044169	biolink:NamedThing	host cell rough endoplasmic reticulum membrane	The lipid bilayer surrounding the host cell rough endoplasmic reticulum.	got7fsn_ti	host rough endoplasmic reticulum membrane						jl	2009-09-04T11:30:38Z						cellular_component											owl:Class	
GO:0044167	biolink:NamedThing	host cell endoplasmic reticulum membrane	The lipid bilayer surrounding the host cell endoplasmic reticulum.	got7fsn_ti	host endoplasmic reticulum membrane						jl	2009-09-04T11:19:23Z						cellular_component											owl:Class	
GO:0048193	biolink:NamedThing	Golgi vesicle transport	The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.	got7fsn_ti	Golgi-derived vesicle transport													biological_process											owl:Class	
GO:0005793	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment	A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi  and Golgi-to-ER transport.	got7fsn_ti	ER-Golgi intermediate compartment|vesicular-tubular cluster|EGTC|ERGIC|endoplasmic reticulum-Golgi transport container|ER-Golgi transport container|pre-Golgi intermediate compartment|VTC											Wikipedia:Vesicular-tubular_cluster		cellular_component											owl:Class	
GO:0019767	biolink:NamedThing	IgE receptor activity	Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0019763	biolink:NamedThing	immunoglobulin receptor activity	Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	FC receptor activity										GO:0016489			molecular_function											owl:Class	
GO:1990189	biolink:NamedThing	peptide-serine-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide.	got7fsn_ti							tb	2013-09-11T20:13:40Z						molecular_function											owl:Class	
GO:0004596	biolink:NamedThing	peptide alpha-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.	got7fsn_ti	N(alpha)-acetyltransferase activity|acetyl-CoA:peptide alpha-N-acetyltransferase activity|acetyl-CoA:peptide nalpha-acetyltransferase activity|amino-terminal amino acid-acetylating enzyme activity|protein N-terminal acetyltransferase activity|beta-endorphin acetyltransferase activity|NAT activity|peptide acetyltransferase activity|nalpha-acetyltransferase activity											Reactome:R-HSA-6814090|MetaCyc:PEPTIDE-ALPHA-N-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0047804	biolink:NamedThing	cysteine-S-conjugate beta-lyase activity	Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate.	got7fsn_ti	L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming)|L-cysteine-S-conjugate thiol-lyase (deaminating) activity|cysteine-S-conjugate b-lyase activity|glutamine transaminase K/cysteine conjugate beta-lyase activity|cysteine conjugate beta-lyase activity											RHEA:18121|MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN|EC:4.4.1.13		molecular_function											owl:Class	
GO:0001879	biolink:NamedThing	detection of yeast	The series of events in which a stimulus from a yeast is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0016046	biolink:NamedThing	detection of fungus	The series of events in which a stimulus from a fungus is received and converted into a molecular signal.	got7fsn_ti	perception of fungus|perception of parasitic fungus|detection of parasitic fungus|perception of fungi|perception of parasitic fungi|detection of fungi|detection of parasitic fungi										GO:0009599|GO:0016047			biological_process											owl:Class	
GO:0102394	biolink:NamedThing	4-hydroxy-L-isoleucine dehydrogenase activity	Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD <=> (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+.	got7fsn_ti												MetaCyc:RXN-13637		molecular_function											owl:Class	
GO:0047345	biolink:NamedThing	ribose-5-phosphate adenylyltransferase activity	Catalysis of the reaction: D-ribose 5-phosphate + ADP + H(+) = ADP-ribose + phosphate.	got7fsn_ti	ADP:D-ribose-5-phosphate adenylyltransferase activity|ADP ribose phosphorylase activity|ADP-ribose phosphorylase activity|ADP:ribose-5-phosphate adenylyltransferase activity|adenosine diphosphoribose phosphorylase activity											MetaCyc:2.7.7.35-RXN|EC:2.7.7.35|RHEA:14529|KEGG_REACTION:R01052		molecular_function											owl:Class	
GO:0070566	biolink:NamedThing	adenylyltransferase activity	Catalysis of the transfer of an adenylyl group to an acceptor.	got7fsn_ti							mah	2009-04-15T11:04:22Z						molecular_function											owl:Class	
GO:0002680	biolink:NamedThing	pro-T cell lineage commitment	The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.	got7fsn_ti	pro-T lymphocyte lineage commitment|pro-T lymphocyte fate commitment|pro-T cell fate commitment													biological_process											owl:Class	
GO:0000446	biolink:NamedThing	nucleoplasmic THO complex	The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits.	got7fsn_ti														cellular_component											owl:Class	
GO:0004834	biolink:NamedThing	tryptophan synthase activity	Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.	got7fsn_ti	L-serine hydro-lyase (adding indoleglycerol-phosphate)|tryptophan desmolase activity|L-tryptophan synthetase activity|indoleglycerol phosphate aldolase activity|L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]|tryptophan synthetase activity											MetaCyc:TRYPSYN-RXN|EC:4.2.1.20|RHEA:10532|KEGG_REACTION:R02722		molecular_function											owl:Class	
GO:0000756	biolink:NamedThing	response to pheromone regulating conjugation with mutual genetic exchange	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion.	got7fsn_ti	response to pheromone triggering conjugation without cellular fusion													biological_process											owl:Class	
GO:0071444	biolink:NamedThing	cellular response to pheromone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.	got7fsn_ti	cellular pheromone response						mah	2009-12-16T04:05:33Z						biological_process											owl:Class	
GO:0050154	biolink:NamedThing	opheline kinase activity	Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+).	got7fsn_ti	ATP:guanidinoethyl-methyl-phosphate phosphotransferase activity											KEGG_REACTION:R04388|EC:2.7.3.7|MetaCyc:OPHELINE-KINASE-RXN|RHEA:17553		molecular_function											owl:Class	
GO:0032892	biolink:NamedThing	positive regulation of organic acid transport	Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	stimulation of organic acid transport|activation of organic acid transport|up-regulation of organic acid transport|upregulation of organic acid transport|up regulation of organic acid transport													biological_process											owl:Class	
GO:0032890	biolink:NamedThing	regulation of organic acid transport	Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0055023	biolink:NamedThing	positive regulation of cardiac muscle tissue growth	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.	got7fsn_ti	up-regulation of cardiac muscle growth|up regulation of cardiac muscle growth|upregulation of cardiac muscle growth|positive regulation of heart muscle growth|activation of cardiac muscle growth|stimulation of cardiac muscle growth													biological_process											owl:Class	
GO:0060421	biolink:NamedThing	positive regulation of heart growth	Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.	got7fsn_ti														biological_process											owl:Class	
GO:0031725	biolink:NamedThing	CXCR6 chemokine receptor binding	Binding to a CXCR6 chemokine receptor.	got7fsn_ti	STRL33 receptor binding|bonzo receptor binding|CXCR6 chemokine receptor ligand													molecular_function											owl:Class	
GO:0045236	biolink:NamedThing	CXCR chemokine receptor binding	Binding to a chemokine receptor in the CXCR family.	got7fsn_ti	CXC chemokine receptor ligand|C-X-C chemokine receptor ligand|alpha chemokine receptor ligand|alpha chemokine receptor binding													molecular_function											owl:Class	
GO:0032197	biolink:NamedThing	transposition, RNA-mediated	Any process involved in a type of transpositional recombination which occurs via an RNA intermediate.	got7fsn_ti	Ty element transposition|retrotransposon transposition|retrotransposition|RNA-mediated transposition|Ty2 element transposition|Ty3 element transposition|Tf transposition|Ty1 element transposition|Class I transposition										GO:0006322|GO:0006319|GO:0006321|GO:0006320	Wikipedia:Transposon##Class_I:_Retrotransposons		biological_process											owl:Class	
GO:0032196	biolink:NamedThing	transposition	Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.	got7fsn_ti												Wikipedia:Transposon		biological_process											owl:Class	
GO:0020023	biolink:NamedThing	kinetoplast	A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.	got7fsn_ti												Wikipedia:Kinetoplast		cellular_component											owl:Class	
GO:0048770	biolink:NamedThing	pigment granule	A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.	got7fsn_ti														cellular_component											owl:Class	
GO:0031410	biolink:NamedThing	cytoplasmic vesicle	A vesicle found in the cytoplasm of a cell.	got7fsn_ti	cytoplasmic membrane bounded vesicle|cytoplasmic, membrane-bounded vesicle|cytoplasmic membrane-enclosed vesicle										GO:0016023	NIF_Subcellular:sao180601769		cellular_component											owl:Class	
GO:0050774	biolink:NamedThing	negative regulation of dendrite morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.	got7fsn_ti	down regulation of dendrite morphogenesis|inhibition of dendrite morphogenesis|down-regulation of dendrite morphogenesis|downregulation of dendrite morphogenesis													biological_process											owl:Class	
GO:0050768	biolink:NamedThing	negative regulation of neurogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.	got7fsn_ti	down regulation of neurogenesis|inhibition of neurogenesis|downregulation of neurogenesis|down-regulation of neurogenesis													biological_process											owl:Class	
GO:0031436	biolink:NamedThing	BRCA1-BARD1 complex	A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.	got7fsn_ti														cellular_component											owl:Class	
GO:1900098	biolink:NamedThing	regulation of plasma cell differentiation	Any process that modulates the frequency, rate or extent of plasma cell differentiation.	got7fsn_ti	regulation of plasma cell development						bf	2012-02-15T10:46:00Z						biological_process											owl:Class	
GO:0002697	biolink:NamedThing	regulation of immune effector process	Any process that modulates the frequency, rate, or extent of an immune effector process.	got7fsn_ti														biological_process											owl:Class	
GO:0060065	biolink:NamedThing	uterus development	The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.	got7fsn_ti	Mullerian tract development													biological_process											owl:Class	
GO:0031798	biolink:NamedThing	type 1 metabotropic glutamate receptor binding	Binding to a type 1 metabotropic glutamate receptor.	got7fsn_ti	type 1 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0098604	biolink:NamedThing	adenosylselenohomocysteinase activity	Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O => Adenosine + Selenohomocysteine.	got7fsn_ti							dos	2014-04-16T10:53:22Z				Reactome:R-HSA-2408532		molecular_function											owl:Class	
GO:0016802	biolink:NamedThing	trialkylsulfonium hydrolase activity	Catalysis of the hydrolysis of a thioether bond, -S-.	got7fsn_ti	thioether hydrolase activity|trialkylsulphonium hydrolase activity											EC:3.3.1.-		molecular_function											owl:Class	
GO:0052581	biolink:NamedThing	(-)-isopiperitenone reductase activity	Catalysis of the reaction: (6R)-isoperitenone + H(+) + NADPH = (2R,5R)-isopulegone + NADP(+).	got7fsn_ti	(+)-cis-isopulegone:NADP+ oxidoreductase activity						ai	2010-08-09T04:42:05Z				RHEA:25649|EC:1.3.1.82|KEGG_REACTION:R06417|MetaCyc:RXN-5161		molecular_function											owl:Class	
GO:0035671	biolink:NamedThing	enone reductase activity	Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+.	got7fsn_ti							bf	2011-02-04T10:59:15Z				MetaCyc:RXN-12267		molecular_function											owl:Class	
GO:0099001	biolink:NamedThing	viral genome ejection through host cell envelope, long flexible tail mechanism	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid.  Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm.	got7fsn_ti	viral long flexible tail ejection system											VZ:3952		biological_process											owl:Class	
GO:0046794	biolink:NamedThing	transport of virus	The directed movement of a virus, or part of a virus, into, out of, or within a host cell.	got7fsn_ti	viral transport|virion transport													biological_process											owl:Class	
GO:0045109	biolink:NamedThing	intermediate filament organization	Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.	got7fsn_ti	intermediate filament organisation													biological_process											owl:Class	
GO:0045104	biolink:NamedThing	intermediate filament cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.	got7fsn_ti	intermediate filament cytoskeleton organisation|intermediate filament cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:0047564	biolink:NamedThing	3-hydroxycyclohexanone dehydrogenase activity	Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione.	got7fsn_ti	3-hydroxycyclohexanone:acceptor 1-oxidoreductase activity											MetaCyc:3-HYDROXYCYCLOHEXANONE-DEHYDROGENASE-RXN|RHEA:15905|EC:1.1.99.26|KEGG_REACTION:R03212		molecular_function											owl:Class	
GO:0102837	biolink:NamedThing	1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8297|EC:1.14.19.35		molecular_function											owl:Class	
GO:2000609	biolink:NamedThing	regulation of thyroid hormone generation	Any process that modulates the frequency, rate or extent of thyroid hormone generation.	got7fsn_ti							yaf	2011-04-18T10:12:14Z						biological_process											owl:Class	
GO:0051171	biolink:NamedThing	regulation of nitrogen compound metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.	got7fsn_ti	regulation of nitrogen metabolic process|regulation of nitrogen metabolism													biological_process											owl:Class	
GO:0006565	biolink:NamedThing	L-serine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.	got7fsn_ti	L-serine breakdown|L-serine catabolism|L-serine degradation											MetaCyc:SERDEG-PWY		biological_process											owl:Class	
GO:0009071	biolink:NamedThing	serine family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.	got7fsn_ti	serine family amino acid degradation|serine family amino acid breakdown|serine family amino acid catabolism													biological_process											owl:Class	
GO:0046843	biolink:NamedThing	dorsal appendage formation	Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.	got7fsn_ti														biological_process											owl:Class	
GO:0044280	biolink:NamedThing	subplasmalemmal coating	Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier.	got7fsn_ti							jl	2010-01-14T03:58:38Z				NIF_Subcellular:sao1938587839		cellular_component											owl:Class	
GO:0050841	biolink:NamedThing	peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine	The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.	got7fsn_ti	peptidyl-trimethyl-lysine hydroxylase activity|peptidyl trimethyl lysine hydroxylase activity											RESID:AA0359		biological_process											owl:Class	
GO:0017185	biolink:NamedThing	peptidyl-lysine hydroxylation	The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine.	got7fsn_ti														biological_process											owl:Class	
GO:0033019	biolink:NamedThing	5-hydroxyvalerate dehydrogenase activity	Catalysis of the reaction: 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH.	got7fsn_ti														molecular_function											owl:Class	
GO:0021989	biolink:NamedThing	olfactory cortex development	The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.	got7fsn_ti														biological_process											owl:Class	
GO:0047378	biolink:NamedThing	acetylalkylglycerol acetylhydrolase activity	Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H(2)O = 1-alkyl-sn-glycerol + acetate + H(+).	got7fsn_ti	alkylacetylglycerol acetylhydrolase activity|2-acetyl-1-alkyl-sn-glycerol acetylhydrolase activity											KEGG_REACTION:R04043|EC:3.1.1.71|RHEA:11552|MetaCyc:3.1.1.71-RXN		molecular_function											owl:Class	
GO:0048469	biolink:NamedThing	cell maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.	got7fsn_ti	functional differentiation													biological_process											owl:Class	
GO:1990723	biolink:NamedThing	cytoplasmic periphery of the nuclear pore complex	Cytoplasm situated in close proximity to a nuclear pore complex.	got7fsn_ti	associated with the nuclear pore	https://github.com/geneontology/go-ontology/issues/21774					sl	2015-04-06T19:26:54Z						cellular_component											owl:Class	
GO:0048471	biolink:NamedThing	perinuclear region of cytoplasm	Cytoplasm situated near, or occurring around, the nucleus.	got7fsn_ti					Note that this term should not be confused with the cellular component term 'nuclear membrane lumen ; GO:0005641', which has the synonym 'perinuclear space'.									cellular_component											owl:Class	
GO:0050636	biolink:NamedThing	vinorine synthase activity	Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine.	got7fsn_ti	acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing)											EC:2.3.1.160|KEGG_REACTION:R05876|MetaCyc:2.3.1.160-RXN|RHEA:24016		molecular_function											owl:Class	
GO:0016055	biolink:NamedThing	Wnt signaling pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.	got7fsn_ti	Wnt receptor signaling pathway|frizzled signaling pathway|frizzled signalling pathway|Wnt receptor signalling pathway|Wg signaling pathway|Wg signalling pathway|Wnt-activated signaling pathway|Wingless signalling pathway|Wingless signaling pathway										GO:0007222			biological_process											owl:Class	
GO:0023003	biolink:NamedThing	nuclear migration to the embryo sac center	Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell.	got7fsn_ti	nuclear migration to the megagametophyte centre|nuclear migration to the megagametophyte center|nuclear migration to the female gametophyte center|nucleus migration to the female gametophyte centre|nuclear migration to the female gametophyte centre|nucleus migration to the female gametophyte center|nuclear migration to the embryo sac centre													biological_process											owl:Class	
GO:0034513	biolink:NamedThing	box H/ACA snoRNA binding	Binding to a box H/ACA small nucleolar RNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0030515	biolink:NamedThing	snoRNA binding	Binding to a small nucleolar RNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0046550	biolink:NamedThing	(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine	The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7.	got7fsn_ti	(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine anabolism from asparagine|(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine formation from asparagine|(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine synthesis from asparagine											RESID:AA0328		biological_process											owl:Class	
GO:0018196	biolink:NamedThing	peptidyl-asparagine modification	The modification of peptidyl-asparagine.	got7fsn_ti														biological_process											owl:Class	
GO:0044324	biolink:NamedThing	regulation of transcription involved in anterior/posterior axis specification	Any process that modulates the frequency, rate or extent of transcription that contributes to the specification of the anterior/posterior axis.	got7fsn_ti							jl	2010-08-04T12:35:41Z						biological_process											owl:Class	
GO:0006357	biolink:NamedThing	regulation of transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.	got7fsn_ti	regulation of transcription from Pol II promoter|regulation of transcription from RNA polymerase II promoter, global|regulation of transcription from RNA polymerase II promoter|regulation of global transcription from Pol II promoter|global transcription regulation from Pol II promoter|regulation of gene-specific transcription from RNA polymerase II promoter										GO:0010551|GO:0006358			biological_process											owl:Class	
GO:0003265	biolink:NamedThing	regulation of primary heart field cardioblast proliferation	Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle.	got7fsn_ti	regulation of first heart field cardiac proliferation|regulation of first heart field cardioblast proliferation|regulation of FHF cardioblast proliferation						dph	2009-10-15T02:25:26Z						biological_process											owl:Class	
GO:0003264	biolink:NamedThing	regulation of cardioblast proliferation	Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti							dph	2009-10-15T02:19:37Z						biological_process											owl:Class	
GO:0031543	biolink:NamedThing	peptidyl-proline dioxygenase activity	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.	got7fsn_ti	prolyl 4-hydroxylase activity|proline hydroxylase activity|prolyl hydroxylase activity|proline,2-oxoglutarate 4-dioxygenase activity													molecular_function											owl:Class	
GO:0097343	biolink:NamedThing	ripoptosome assembly	The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.	got7fsn_ti							pr	2012-06-18T12:57:20Z						biological_process											owl:Class	
GO:0065003	biolink:NamedThing	protein-containing complex assembly	The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.	got7fsn_ti	chaperone activity|macromolecule complex assembly|macromolecular complex assembly|protein complex assembly|protein complex formation										GO:0006461			biological_process											owl:Class	
GO:0022836	biolink:NamedThing	gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.	got7fsn_ti														molecular_function											owl:Class	
GO:0015267	biolink:NamedThing	channel activity	Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.	got7fsn_ti	channel-forming toxin activity|pore class transporter activity|nonselective channel activity|substrate-specific channel activity|channel/pore class transporter activity|pore activity|alpha-type channel activity										GO:0015268|GO:0022838|GO:0015249	TC:1|Reactome:R-HSA-3779381|Reactome:R-HSA-8953430		molecular_function											owl:Class	
GO:0047036	biolink:NamedThing	codeinone reductase (NADPH) activity	Catalysis of the reaction: codeine + NADP(+) = codeinone + H(+) + NADPH.	got7fsn_ti	codeine:NADP+ oxidoreductase activity											KEGG_REACTION:R05124|RHEA:19209|EC:1.1.1.247|MetaCyc:1.1.1.247-RXN		molecular_function											owl:Class	
GO:0018694	biolink:NamedThing	p-cymene methyl hydroxylase activity	Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol.	got7fsn_ti												EC:1.14.15.25|RHEA:51604|UM-BBD_reactionID:r0392|MetaCyc:RXN-661		molecular_function											owl:Class	
GO:0016725	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on CH or CH2 groups, other acceptors											EC:1.17.-.-		molecular_function											owl:Class	
GO:0140561	biolink:NamedThing	EGF-domain serine glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16869					pg	2020-11-25T14:19:23Z				RHEA:58116|EC:2.4.1.376		molecular_function											owl:Class	
GO:0050197	biolink:NamedThing	phytanate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H(+) + phytanoyl-CoA.	got7fsn_ti	phytanoyl-CoA ligase activity|phytanate:CoA ligase (AMP-forming)											RHEA:21380|EC:6.2.1.24|Reactome:R-HSA-389622|KEGG_REACTION:R03631|MetaCyc:PHYTANATE--COA-LIGASE-RXN		molecular_function											owl:Class	
GO:0045485	biolink:NamedThing	omega-6 fatty acid desaturase activity	Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain.	got7fsn_ti												Reactome:R-HSA-2046092|Reactome:R-HSA-2046089		molecular_function											owl:Class	
GO:0019874	biolink:NamedThing	6-aminohexanoate-cyclic-dimer hydrolase activity	Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate.	got7fsn_ti	1,8-diazacyclotetradecane-2,9-dione lactamhydrolase activity											KEGG_REACTION:R03448|UM-BBD_reactionID:r1097|MetaCyc:3.5.2.12-RXN|EC:3.5.2.12|RHEA:16225		molecular_function											owl:Class	
GO:0031582	biolink:NamedThing	replication fork arrest at rDNA repeats	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.	got7fsn_ti	replication fork blocking at rDNA repeats|replication fork arrest at ribosomal DNA repeats													biological_process											owl:Class	
GO:0043007	biolink:NamedThing	maintenance of rDNA	Any process involved in sustaining the fidelity and copy number of rDNA repeats.	got7fsn_ti	ribosomal DNA maintenance|rDNA maintenance													biological_process											owl:Class	
GO:0008595	biolink:NamedThing	anterior/posterior axis specification, embryo	The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.	got7fsn_ti	anterior/posterior axis determination, embryo													biological_process											owl:Class	
GO:0009948	biolink:NamedThing	anterior/posterior axis specification	The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	got7fsn_ti	anterior/posterior axis determination													biological_process											owl:Class	
GO:0003021	biolink:NamedThing	detection of increased carbon dioxide by chemoreceptor signaling	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.	got7fsn_ti	detection of increased carbon dioxide by chemoreceptor signalling													biological_process											owl:Class	
GO:0003031	biolink:NamedThing	detection of carbon dioxide	The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0043731	biolink:NamedThing	6-hydroxynicotinate 3-monooxygenase activity	Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD.	got7fsn_ti												RHEA:27333|EC:1.14.13.114|MetaCyc:RXN-7573		molecular_function											owl:Class	
GO:0052751	biolink:NamedThing	GDP-mannose hydrolase activity	Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate.	got7fsn_ti	GDP-mannose pyrophosphatase activity						ai	2011-09-21T04:11:30Z						molecular_function											owl:Class	
GO:0016462	biolink:NamedThing	pyrophosphatase activity	Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.	got7fsn_ti												Reactome:R-HSA-6810472		molecular_function											owl:Class	
GO:0031709	biolink:NamedThing	gastrin-releasing peptide receptor binding	Binding to a gastrin-releasing peptide receptor.	got7fsn_ti	GRP receptor binding|gastrin-releasing peptide receptor ligand													molecular_function											owl:Class	
GO:0031705	biolink:NamedThing	bombesin receptor binding	Binding to a bombesin receptor.	got7fsn_ti	bombesin receptor ligand													molecular_function											owl:Class	
GO:0019702	biolink:NamedThing	protein-arginine N5-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine.	got7fsn_ti	type IV protein arginine methyltransferase activity|protein-arginine delta-N-methyltransferase activity|type IV PRMT activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming)				This enzyme, characterized from the yeast Saccharomyces cerevisiae, methylates the delta-nitrogen atom of arginine residues within proteins. Among its substrates are Arg67 of the ribosomal protein L12.							EC:2.1.1.322|RHEA:48116		molecular_function											owl:Class	
GO:0097306	biolink:NamedThing	cellular response to alcohol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.	got7fsn_ti							pr	2012-05-15T03:49:51Z						biological_process											owl:Class	
GO:0140527	biolink:NamedThing	reciprocal homologous recombination	A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18777					pg	2020-09-29T15:08:11Z						biological_process											owl:Class	
GO:0035825	biolink:NamedThing	homologous recombination	A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules.	got7fsn_ti	chromosomal crossover|interstrand DNA recombination|reciprocal DNA recombination|interchromosomal DNA recombination	https://github.com/geneontology/go-ontology/issues/18777					bf	2011-05-04T01:23:31Z				Wikipedia:Chromosomal_crossover		biological_process											owl:Class	
GO:0047945	biolink:NamedThing	L-glutamine:pyruvate aminotransferase activity	Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.	got7fsn_ti	glutamine--pyruvate aminotransferase activity|glutamine-alpha-keto acid transamidase activity|glutaminase II activity|glutamine transaminase L activity|L-glutamine transaminase L|glutamine-alpha-keto acid transaminase activity|glutamine--oxo-acid transaminase activity|gamma-glutaminyltransferase activity|glutamine-oxo acid aminotransferase activity|glutamine transaminase activity|glutamine-pyruvate transaminase activity|glutamine-keto acid aminotransferase activity											KEGG_REACTION:R00576|RHEA:10400|EC:2.6.1.15|Reactome:R-HSA-893616|MetaCyc:GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0070548	biolink:NamedThing	L-glutamine aminotransferase activity	Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0000952	biolink:NamedThing	aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.	got7fsn_ti														biological_process											owl:Class	
GO:0009074	biolink:NamedThing	aromatic amino acid family catabolic process	The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).	got7fsn_ti	aromatic amino acid family degradation|aromatic amino acid family breakdown|aromatic amino acid family catabolism													biological_process											owl:Class	
GO:0140061	biolink:NamedThing	5-hydroxymethylcytosine dioxygenase activity	Catalysis of the reaction: 5-hydroxymethylcytosine + 2-oxoglutarate + O2 = 5-formylcytosine + succinate + CO2.	got7fsn_ti	5hmC dioxygenase						pg	2017-07-20T09:54:50Z						molecular_function											owl:Class	
GO:0031511	biolink:NamedThing	Mis6-Sim4 complex	A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.	got7fsn_ti	Mis6 centromere subcomplex|Mis6-Mal2-Sim4 centromere complex|Sim4 complex													cellular_component											owl:Class	
GO:0033701	biolink:NamedThing	dTDP-galactose 6-dehydrogenase activity	Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+.	got7fsn_ti	thymidine-diphosphate-galactose dehydrogenase activity|dTDPgalactose 6-dehydrogenase activity|dTDP-D-galactose:NADP+ 6-oxidoreductase activity											RHEA:12396|MetaCyc:DTDP-GALACTOSE-6-DEHYDROGENASE-RXN|EC:1.1.1.186		molecular_function											owl:Class	
GO:0046902	biolink:NamedThing	regulation of mitochondrial membrane permeability	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.	got7fsn_ti	regulation of mitochondrial envelope permeability|regulation of transport across mitochondrial membrane													biological_process											owl:Class	
GO:0044777	biolink:NamedThing	single-stranded DNA-binding protein complex	A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair.	got7fsn_ti	SSB complex						jl	2013-03-14T13:14:00Z						cellular_component											owl:Class	
GO:0010018	biolink:NamedThing	far-red light signaling pathway	The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti	far red light signalling pathway|far-red light signal transduction|far red signaling pathway													biological_process											owl:Class	
GO:0010017	biolink:NamedThing	red or far-red light signaling pathway	The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti	red/far red light signaling pathway|red or far-red light signalling pathway|red or far-red light signal transduction|phytochrome signaling pathway|red or far red light signaling pathway													biological_process											owl:Class	
GO:0048165	biolink:NamedThing	fused antrum stage	The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.	got7fsn_ti	mammalian oogenesis stage 8													biological_process											owl:Class	
GO:0061666	biolink:NamedThing	UFM1 ligase activity	Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S --> X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3						dph	2014-11-06T14:02:37Z						molecular_function											owl:Class	
GO:0050165	biolink:NamedThing	pantetheine kinase activity	Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate.	got7fsn_ti	pantetheine kinase (phosphorylating)|ATP:pantetheine 4'-phosphotransferase activity											RHEA:22472|MetaCyc:PANTETHEINE-KINASE-RXN|EC:2.7.1.34		molecular_function											owl:Class	
GO:0072147	biolink:NamedThing	glomerular parietal epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.	got7fsn_ti	Bowman's capsule cell fate commitment						mah	2010-02-24T02:00:52Z						biological_process											owl:Class	
GO:0072314	biolink:NamedThing	glomerular epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.	got7fsn_ti							mah	2010-04-09T07:02:25Z						biological_process											owl:Class	
GO:0014882	biolink:NamedThing	regulation of myofibril number	Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.	got7fsn_ti	change of myofibril number													biological_process											owl:Class	
GO:0014738	biolink:NamedThing	regulation of muscle hyperplasia	Any process that modulates the frequency, rate or extent of muscle hyperplasia.	got7fsn_ti														biological_process											owl:Class	
GO:0033379	biolink:NamedThing	maintenance of protease location in T cell secretory granule	A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of protease localization in T lymphocyte secretory granule|maintenance of protease localization in T-cell secretory granule|maintenance of protease localization in T-lymphocyte secretory granule|maintenance of protease localization in T cell secretory granule													biological_process											owl:Class	
GO:0033377	biolink:NamedThing	maintenance of protein location in T cell secretory granule	A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of protein localization in T lymphocyte secretory granule|maintenance of protein localization in T cell secretory granule|maintenance of protein localization in T-cell secretory granule|maintenance of protein localization in T-lymphocyte secretory granule													biological_process											owl:Class	
GO:0031746	biolink:NamedThing	type 1 cysteinyl leukotriene receptor binding	Binding to a type 1 cysteinyl leukotriene receptor.	got7fsn_ti	type 1 cysteinyl leukotriene receptor ligand													molecular_function											owl:Class	
GO:0031745	biolink:NamedThing	cysteinyl leukotriene receptor binding	Binding to a cysteinyl leukotriene receptor.	got7fsn_ti	cysteinyl leukotriene receptor ligand													molecular_function											owl:Class	
GO:0008241	biolink:NamedThing	peptidyl-dipeptidase activity	Catalysis of the release of C-terminal dipeptides from a polypeptide chain.	got7fsn_ti												EC:3.4.15.-		molecular_function											owl:Class	
GO:0042383	biolink:NamedThing	sarcolemma	The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.	got7fsn_ti												Wikipedia:Sarcolemma		cellular_component											owl:Class	
GO:0005886	biolink:NamedThing	plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	got7fsn_ti	cell membrane|bacterial inner membrane|plasma membrane lipid bilayer|cytoplasmic membrane|plasmalemma|juxtamembrane|inner endospore membrane|cellular membrane										GO:0005904	Wikipedia:Cell_membrane|NIF_Subcellular:sao1663586795		cellular_component											owl:Class	
GO:0072688	biolink:NamedThing	SHREC complex localization	Any process in which a SHREC complex is transported to, or maintained in, a specific location.	got7fsn_ti	SHREC complex localisation|establishment and maintenance of SHREC complex localization						mah	2011-07-20T12:51:49Z						biological_process											owl:Class	
GO:0032351	biolink:NamedThing	negative regulation of hormone metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.	got7fsn_ti	downregulation of hormone metabolic process|negative regulation of hormone metabolism|down-regulation of hormone metabolic process|down regulation of hormone metabolic process|inhibition of hormone metabolic process													biological_process											owl:Class	
GO:0002637	biolink:NamedThing	regulation of immunoglobulin production	Any process that modulates the frequency, rate, or extent of immunoglobulin production.	got7fsn_ti	regulation of immunoglobulin secretion|regulation of immunoglobulin biosynthetic process|regulation of antibody production										GO:0002640|GO:0051023			biological_process											owl:Class	
GO:0002032	biolink:NamedThing	desensitization of G protein-coupled receptor signaling pathway by arrestin	The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins.	got7fsn_ti	arrestin-mediated desensitization of G-protein coupled receptor protein signaling pathway|desensitization of G-protein coupled receptor protein signaling pathway by arrestin|arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway|arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway													biological_process											owl:Class	
GO:0032091	biolink:NamedThing	negative regulation of protein binding	Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.	got7fsn_ti	downregulation of protein binding|down-regulation of protein binding|inhibition of protein binding|down regulation of protein binding													biological_process											owl:Class	
GO:0030018	biolink:NamedThing	Z disc	Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.	got7fsn_ti	Z disk|Z band|Z line													cellular_component											owl:Class	
GO:0003987	biolink:NamedThing	acetate-CoA ligase activity	Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.	got7fsn_ti	ACS|acetyl-CoA synthetase activity|acetyl CoA ligase activity|acyl-activating enzyme activity|acetyl activating enzyme|acetate thiokinase activity|acetyl-CoA synthase activity|acetyl coenzyme A synthetase activity|acetic thiokinase activity|acetate to acetyl-CoA|short-chain acyl-coenzyme A synthetase activity|acetyl-coenzyme A synthase activity|acetyl-activating enzyme activity|short chain fatty acyl-CoA synthetase activity|acetate:CoA ligase (AMP-forming)|acetyl CoA synthase activity											Reactome:R-HSA-71735|Reactome:R-HSA-8875071|Reactome:R-HSA-449911|RHEA:23176|EC:6.2.1.1|MetaCyc:ACETATE--COA-LIGASE-RXN		molecular_function											owl:Class	
GO:0035989	biolink:NamedThing	tendon development	The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.	got7fsn_ti	sinew development						bf	2011-08-26T04:14:30Z						biological_process											owl:Class	
GO:0061448	biolink:NamedThing	connective tissue development	The progression of a connective tissue over time, from its formation to the mature structure.	got7fsn_ti							dph	2012-03-22T12:53:41Z						biological_process											owl:Class	
GO:0036348	biolink:NamedThing	hydantoin racemase activity	Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin.	got7fsn_ti							bf	2012-09-19T10:47:56Z				MetaCyc:RXN-9781|RHEA:46624|KEGG_REACTION:R09704|EC:5.1.99.5		molecular_function											owl:Class	
GO:0016854	biolink:NamedThing	racemase and epimerase activity	Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.	got7fsn_ti	racemase and epimerase activity, acting on other compounds				Note that 'epimerase' refers to the conversion of an epimer into its diastereoisomer, and 'racemase' refers to the interconversion of the two enantiomers of a chiral compound.							EC:5.1.-.-		molecular_function											owl:Class	
GO:0001595	biolink:NamedThing	angiotensin receptor activity	Combining with angiotensin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0030320	biolink:NamedThing	cellular monovalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of monovalent inorganic anions at the level of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0055083	biolink:NamedThing	monovalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0031497	biolink:NamedThing	chromatin assembly	The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.	got7fsn_ti	establishment of chromatin architecture|chromatin maintenance													biological_process											owl:Class	
GO:0003093	biolink:NamedThing	regulation of glomerular filtration	Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.	got7fsn_ti														biological_process											owl:Class	
GO:0000839	biolink:NamedThing	Hrd1p ubiquitin ligase ERAD-L complex	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.	got7fsn_ti														cellular_component											owl:Class	
GO:0000836	biolink:NamedThing	Hrd1p ubiquitin ligase complex	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).	got7fsn_ti	HRD1 ubiquitin ligase complex													cellular_component											owl:Class	
GO:0061196	biolink:NamedThing	fungiform papilla development	The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.	got7fsn_ti							dph	2010-07-27T12:23:48Z						biological_process											owl:Class	
GO:0035502	biolink:NamedThing	metanephric part of ureteric bud development	The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.	got7fsn_ti							bf	2010-04-29T03:22:21Z						biological_process											owl:Class	
GO:0035295	biolink:NamedThing	tube development	The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.	got7fsn_ti														biological_process											owl:Class	
GO:0060513	biolink:NamedThing	prostatic bud formation	The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.	got7fsn_ti	primary prostate bud formation|prostate gland formation|prostate ductal budding													biological_process											owl:Class	
GO:0035783	biolink:NamedThing	CD4-positive, alpha-beta T cell costimulation	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.	got7fsn_ti	CD4-positive, alpha beta T cell costimulation						bf	2011-04-04T11:28:52Z						biological_process											owl:Class	
GO:2000516	biolink:NamedThing	positive regulation of CD4-positive, alpha-beta T cell activation	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.	got7fsn_ti							ebc	2011-03-22T10:37:06Z						biological_process											owl:Class	
GO:0106069	biolink:NamedThing	synapsis initiation complex	A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase.	got7fsn_ti							hjd	2017-11-22T18:50:26Z						cellular_component											owl:Class	
GO:0106068	biolink:NamedThing	SUMO ligase complex	A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex.	got7fsn_ti	SUMO transferase complex|SUMO-protein ligase complex|Sumoylation complex						hjd	2017-11-22T18:46:00Z						cellular_component											owl:Class	
GO:0009606	biolink:NamedThing	tropism	The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it.	got7fsn_ti												Wikipedia:Tropism		biological_process											owl:Class	
GO:0140395	biolink:NamedThing	averantin hydroxylase activity	Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O(2) <=> (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H(2)O. Involved in aflatoxin biosynthesis.	got7fsn_ti							pg	2019-11-29T08:48:23Z				MetaCyc:RXN-9482|RHEA:35575|EC:1.14.14.116		molecular_function											owl:Class	
GO:0036422	biolink:NamedThing	heptaprenyl diphosphate synthase activity	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate.	got7fsn_ti	heptaprenyl pyrophosphate synthase activity|HepPP synthase activity|all-trans-heptaprenyl-diphosphate synthase activity|heptaprenyl pyrophosphate synthetase activity						bf	2013-09-16T11:50:41Z				RHEA:27794|MetaCyc:TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN|EC:2.5.1.30		molecular_function											owl:Class	
GO:0032299	biolink:NamedThing	ribonuclease H2 complex	A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.	got7fsn_ti	RNase H2 complex													cellular_component											owl:Class	
GO:0035335	biolink:NamedThing	peptidyl-tyrosine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.	got7fsn_ti							bf	2010-03-01T01:09:14Z						biological_process											owl:Class	
GO:0006470	biolink:NamedThing	protein dephosphorylation	The process of removing one or more phosphoric residues from a protein.	got7fsn_ti	protein amino acid dephosphorylation													biological_process											owl:Class	
GO:0050963	biolink:NamedThing	detection of electrical stimulus involved in sensory perception	The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception.	got7fsn_ti	sensory detection of electrical stimulus during sensory perception|sensory perception, sensory transduction of electrical stimulus|sensory transduction of electrical stimulus|sensory perception, sensory detection of electrical stimulus|sensory transduction of electrical stimulus during sensory perception|sensory detection of electrical stimulus													biological_process											owl:Class	
GO:0019569	biolink:NamedThing	L-arabinose catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate.	got7fsn_ti	L-arabinose degradation to xylulose 5-phosphate|L-arabinose breakdown to xylulose 5-phosphate											MetaCyc:ARABCAT-PWY		biological_process											owl:Class	
GO:0004164	biolink:NamedThing	diphthine synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.	got7fsn_ti	diphthine methyltransferase activity|S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity|S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity											RHEA:20145|MetaCyc:RXN-11370|EC:2.1.1.98|Reactome:R-HSA-5358484		molecular_function											owl:Class	
GO:0009940	biolink:NamedThing	amino-terminal vacuolar sorting propeptide binding	Binding to an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles.	got7fsn_ti														molecular_function											owl:Class	
GO:0010209	biolink:NamedThing	vacuolar sorting signal binding	Binding to a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole.	got7fsn_ti														molecular_function											owl:Class	
GO:0043409	biolink:NamedThing	negative regulation of MAPK cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.	got7fsn_ti	negative regulation of mitogen activated protein kinase cascade|negative regulation of MAPKKK cascade|down regulation of MAPKKK cascade|negative regulation of mitogen-activated protein kinase cascade|negative regulation of MAP kinase cascade|negative regulation of mitogen-activated protein kinase kinase kinase cascade|negative regulation of mitogen activated protein kinase kinase kinase cascade|inhibition of MAPKKK cascade|negative regulation of MAP kinase kinase kinase cascade|down-regulation of MAPKKK cascade|downregulation of MAPKKK cascade|down regulation of MAPK cascade|inhibition of MAPK cascade|downregulation of MAPK cascade|down-regulation of MAPK cascade													biological_process											owl:Class	
GO:1902532	biolink:NamedThing	negative regulation of intracellular signal transduction	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.	got7fsn_ti	down regulation of signal transduction via intracellular signaling cascade|negative regulation of intracellular protein kinase cascade|down-regulation of signal transduction via intracellular signaling cascade|down regulation of intracellular signaling cascade|inhibition of intracellular signal transduction pathway|downregulation of intracellular signaling pathway|down-regulation of signal transmission via intracellular cascade|down regulation of intracellular signal transduction|inhibition of intracellular signaling chain|down regulation of intracellular signal transduction pathway|inhibition of intracellular signaling pathway|negative regulation of intracellular signaling chain|down-regulation of intracellular signal transduction pathway|downregulation of signal transmission via intracellular cascade|negative regulation of intracellular signaling cascade|downregulation of intracellular signaling chain|negative regulation of intracellular signaling pathway|down-regulation of intracellular signaling cascade|downregulation of signal transduction via intracellular signaling cascade|downregulation of intracellular signaling cascade|negative regulation of signal transduction via intracellular signaling cascade|inhibition of intracellular signal transduction|downregulation of intracellular signal transduction|inhibition of signal transduction via intracellular signaling cascade|inhibition of signal transmission via intracellular cascade|negative regulation of signal transmission via intracellular cascade|down regulation of signal transmission via intracellular cascade|down-regulation of intracellular signaling chain|down-regulation of intracellular signaling pathway|downregulation of intracellular signal transduction pathway|negative regulation of intracellular signal transduction pathway|down regulation of intracellular signaling chain|down regulation of intracellular signaling pathway|inhibition of intracellular signaling cascade|down-regulation of intracellular signal transduction						bf	2013-12-02T11:33:01Z			GO:0010741			biological_process											owl:Class	
GO:0098880	biolink:NamedThing	maintenance of postsynaptic specialization structure	A process which maintains the organization and the arrangement of proteins in the presynaptic specialization.	got7fsn_ti														biological_process											owl:Class	
GO:0097106	biolink:NamedThing	postsynaptic density organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.	got7fsn_ti	post synaptic density organization|PSD organization|postsynaptic density organisation|post-synaptic density organization						pr	2011-07-27T05:17:12Z						biological_process											owl:Class	
GO:0016234	biolink:NamedThing	inclusion body	A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.	got7fsn_ti	neuronal cytoplasmic inclusion|cellular inclusion											NIF_Subcellular:sao120573470|Wikipedia:Inclusion_bodies		cellular_component											owl:Class	
GO:0021627	biolink:NamedThing	olfactory nerve morphogenesis	The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	got7fsn_ti	CN I morphogenesis													biological_process											owl:Class	
GO:0021602	biolink:NamedThing	cranial nerve morphogenesis	The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	got7fsn_ti														biological_process											owl:Class	
GO:0036396	biolink:NamedThing	RNA N6-methyladenosine methyltransferase complex	A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).	got7fsn_ti	WMM complex|METTL3-METTL14-WTAP methyltransferase complex|MIS complex|Mum2, Ime4, and Slz1 complex|m6A methyltransferase complex|m(6)A writer complex						bf	2013-07-15T10:17:50Z						cellular_component											owl:Class	
GO:0034708	biolink:NamedThing	methyltransferase complex	A protein complex that possesses methyltransferase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0060740	biolink:NamedThing	prostate gland epithelium morphogenesis	The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.	got7fsn_ti							dph	2009-06-16T09:23:22Z						biological_process											owl:Class	
GO:0005749	biolink:NamedThing	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.	got7fsn_ti	mitochondrial fumarate reductase complex										GO:0009362|GO:0008136|GO:0019738|GO:0030390			cellular_component											owl:Class	
GO:0047527	biolink:NamedThing	2,3-dihydroxybenzoate-serine ligase activity	Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.	got7fsn_ti	N-(2,3-dihydroxybenzoyl)-serine synthetase activity|2,3-dihydroxybenzoate:L-serine ligase activity|2,3-dihydroxybenzoylserine synthetase activity											RHEA:30571|MetaCyc:23-DIHYDROXYBENZOATE--SERINE-LIGASE-RXN|EC:6.3.2.14		molecular_function											owl:Class	
GO:0060627	biolink:NamedThing	regulation of vesicle-mediated transport	Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.	got7fsn_ti							dph	2009-05-18T02:29:43Z						biological_process											owl:Class	
GO:0000955	biolink:NamedThing	amino acid catabolic process via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.	got7fsn_ti														biological_process											owl:Class	
GO:0052746	biolink:NamedThing	inositol phosphorylation	The process of introducing one or more phosphate groups into inositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms.	got7fsn_ti	myo-inositol phosphorylation|inositol and derivative phosphorylation|myo-inositol and derivative phosphorylation						ai	2011-09-14T01:55:23Z						biological_process											owl:Class	
GO:0006020	biolink:NamedThing	inositol metabolic process	The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.	got7fsn_ti	myo-inositol metabolism|inositol metabolism|myo-inositol metabolic process|vitamin Bh metabolic process|vitamin Bh metabolism											Wikipedia:Inositol		biological_process											owl:Class	
GO:0036262	biolink:NamedThing	granulysin production	The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2012-06-18T02:11:15Z						biological_process											owl:Class	
GO:0002440	biolink:NamedThing	production of molecular mediator of immune response	The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	production of cellular mediator of immune response				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0051998	biolink:NamedThing	protein carboxyl O-methyltransferase activity	Catalysis of the transfer of a methyl group to a carboxyl group on a protein.	got7fsn_ti	protein carboxyl methyltransferase activity						ai	2010-07-20T09:23:00Z						molecular_function											owl:Class	
GO:0097642	biolink:NamedThing	calcitonin family receptor activity	Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.	got7fsn_ti							pr	2014-09-08T15:32:19Z						molecular_function											owl:Class	
GO:0102059	biolink:NamedThing	2-cis,6-cis-farnesyl pyrophosphate synthase activity	Catalysis of the reaction: dimethylallyl diphosphate + 2 isopentenyl diphosphate <=> 2 diphosphate + (2Z,6Z)-farnesyl diphosphate.	got7fsn_ti	neryl-diphosphate:isopentenyl-diphosphate cistransferase activity										GO:0102192	RHEA:27810|MetaCyc:RXN-10481|MetaCyc:RXN-11973|EC:2.5.1.92		molecular_function											owl:Class	
GO:0019620	biolink:NamedThing	aerobic benzoate metabolic process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen.	got7fsn_ti	aerobic benzoate metabolism													biological_process											owl:Class	
GO:0018874	biolink:NamedThing	benzoate metabolic process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.	got7fsn_ti	benzoate metabolism											UM-BBD_pathwayID:benz2|MetaCyc:P321-PWY		biological_process											owl:Class	
GO:0034924	biolink:NamedThing	cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity	Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2.	got7fsn_ti												UM-BBD_reactionID:r0940		molecular_function											owl:Class	
GO:0097409	biolink:NamedThing	glial cytoplasmic inclusion	Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy.	got7fsn_ti	Papp-Lantos body|GCI						pr	2012-10-31T13:55:11Z				NIF_Subcellular:nlx_subcell_20090703		cellular_component											owl:Class	
GO:0038157	biolink:NamedThing	granulocyte-macrophage colony-stimulating factor signaling pathway	A series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors.	got7fsn_ti	granulocyte-macrophage colony-stimulating factor receptor signaling pathway|granulocyte-macrophage colony-stimulating factor signalling pathway|GM-CSF receptor signaling pathway|GM-CSF signaling pathway|CSF2 signaling pathway						bf	2012-05-14T01:22:15Z						biological_process											owl:Class	
GO:0150086	biolink:NamedThing	multiple synapse bouton	A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.	got7fsn_ti	multisynapse|multiple spine synapse bouton|MSB|multi-synapse bouton|multi-synapse|multiple synapse|multisynapse bouton|multiple-synapse bouton|multisynaptic bouton|multi-synaptic bouton						bc	2018-08-08T13:21:17Z						cellular_component											owl:Class	
GO:0043195	biolink:NamedThing	terminal bouton	Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.	got7fsn_ti	bouton|synaptic bouton|terminal button|presynaptic bouton											NIF_Subcellular:sao187426937		cellular_component											owl:Class	
GO:0030844	biolink:NamedThing	positive regulation of intermediate filament depolymerization	Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization.	got7fsn_ti	up regulation of intermediate filament depolymerization|positive regulation of intermediate filament polymerization and/or depolymerization|activation of intermediate filament depolymerization|upregulation of intermediate filament depolymerization|up-regulation of intermediate filament depolymerization|stimulation of intermediate filament depolymerization				Note that this term was split from 'positive regulation of intermediate filament polymerization and/or depolymerization ; GO:0045826' (sibling term 'positive regulation of intermediate filament polymerization ; GO:0030841').									biological_process											owl:Class	
GO:0015374	biolink:NamedThing	neutral, basic amino acid:sodium:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in).	got7fsn_ti	neutral, cationic amino acid:sodium:chloride symporter activity													molecular_function											owl:Class	
GO:0005283	biolink:NamedThing	amino acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).	got7fsn_ti	insulin-activated sodium:amino acid transporter activity|threonine/serine:sodium symporter activity|sodium/excitatory amino acid symporter activity|sodium/excitatory amino acid cotransporter activity|insulin-activated sodium/amino acid transporter activity|glutamate/aspartate:sodium symporter activity|sodium:amino acid symporter activity|sodium:amino acid transporter activity|insulin-activated sodium:amino acid symporter activity|isoleucine/valine:sodium symporter activity|sodium/amino acid transporter activity										GO:0005285|GO:0005284			molecular_function											owl:Class	
GO:0002428	biolink:NamedThing	antigen processing and presentation of peptide antigen via MHC class Ib	The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.	got7fsn_ti	peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0002243	biolink:NamedThing	detection of parasitic plant	The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0002241	biolink:NamedThing	response to parasitic plant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant.	got7fsn_ti														biological_process											owl:Class	
GO:0071904	biolink:NamedThing	protein N-linked N-acetylgalactosaminylation via asparagine	A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue.	got7fsn_ti	protein amino acid N-linked N-acetylgalactosaminylation via asparagine						mah	2010-09-15T03:52:28Z				RESID:AA0420		biological_process											owl:Class	
GO:0140670	biolink:NamedThing	ATP-dependent cohesin unloading activity	Facilitating a conformational change to unload a cohesin complex from sister chromatids, driven by ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21700					pg	2021-06-24T13:36:05Z						molecular_function											owl:Class	
GO:0140083	biolink:NamedThing	ATP-dependent protein-DNA unloading activity	Facilitating the removal of a protein or protein complex from a DNA molecule driven by ATP hydrolysis. This can be achieved for example by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction.	got7fsn_ti	protein-DNA unloading ATPase activity	https://github.com/geneontology/go-ontology/issues/13992|https://github.com/geneontology/go-ontology/issues/21612					pg	2017-08-08T14:50:27Z						molecular_function											owl:Class	
GO:0034580	biolink:NamedThing	4-methyloctanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0924|EC:1.3.99.-		molecular_function											owl:Class	
GO:1990442	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to nitrosative stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.	got7fsn_ti	nitrosative stress-induced intrinsic apoptotic signaling pathway|nitrosative stress-induced apoptosis						bf	2014-07-31T14:28:16Z						biological_process											owl:Class	
GO:0071500	biolink:NamedThing	cellular response to nitrosative stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.	got7fsn_ti							mah	2009-12-18T02:49:46Z						biological_process											owl:Class	
GO:0030658	biolink:NamedThing	transport vesicle membrane	The lipid bilayer surrounding a transport vesicle.	got7fsn_ti	constitutive secretory pathway transport vesicle membrane|secretory vesicle membrane													cellular_component											owl:Class	
GO:0030659	biolink:NamedThing	cytoplasmic vesicle membrane	The lipid bilayer surrounding a cytoplasmic vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0031570	biolink:NamedThing	DNA integrity checkpoint signaling	A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.	got7fsn_ti	signal transduction involved in DNA integrity checkpoint|DNA integrity checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072401			biological_process											owl:Class	
GO:0000075	biolink:NamedThing	cell cycle checkpoint signaling	A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.	got7fsn_ti	G1/S checkpoint|cell cycle checkpoint|G2/M transition checkpoint|signal transduction involved in cell cycle checkpoint|signal transduction involved in G2/M transition checkpoint|G2/M checkpoint|G1/S transition checkpoint	https://github.com/geneontology/go-ontology/issues/20935			This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.						GO:0071779|GO:0072407|GO:0072404|GO:0031576|GO:0072395	Wikipedia:Cell_cycle_checkpoint		biological_process											owl:Class	
GO:0072740	biolink:NamedThing	cellular response to anisomycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.	got7fsn_ti							mah	2012-07-17T10:33:00Z						biological_process											owl:Class	
GO:0072739	biolink:NamedThing	response to anisomycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.	got7fsn_ti							mah	2012-07-17T10:33:00Z						biological_process											owl:Class	
GO:0044621	biolink:NamedThing	modulation of cell migration in other organism	The process in which an organism effects a change in the process of cell migration in a second organism.	got7fsn_ti	regulation of cell migration in other organism						jl	2012-07-04T04:40:13Z						biological_process											owl:Class	
GO:0035821	biolink:NamedThing	modulation of process of other organism	The process in which an organism effects a change in the structure or processes of another organism.	got7fsn_ti	regulation of morphology or physiology of other organism|regulation of physiological process of other organism|modification of morphology or physiology of other organism|regulation of morphology of other organism|regulation of physiology of other organism	https://github.com/geneontology/go-ontology/issues/18605					bf	2011-04-21T01:31:51Z						biological_process											owl:Class	
GO:0019232	biolink:NamedThing	perception of rate of movement	The series of events by which an organism senses the speed and direction of movement of the body and its parts.	got7fsn_ti	kinesthesia													biological_process											owl:Class	
GO:0019230	biolink:NamedThing	proprioception	The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.	got7fsn_ti												Wikipedia:Proprioception		biological_process											owl:Class	
GO:0002117	biolink:NamedThing	amphibian larval development	The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.	got7fsn_ti														biological_process											owl:Class	
GO:0035398	biolink:NamedThing	helper T cell enhancement of T cell mediated immune response	Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.	got7fsn_ti	helper T cell enhancement of T cell mediated immunity|provision of T cell help to T cell						bf	2010-03-23T10:40:00Z						biological_process											owl:Class	
GO:0035397	biolink:NamedThing	helper T cell enhancement of adaptive immune response	Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.	got7fsn_ti	provision of T cell help						bf	2010-03-23T10:38:31Z						biological_process											owl:Class	
GO:0035363	biolink:NamedThing	histone locus body	A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body.	got7fsn_ti	HLB						bf	2010-03-10T10:44:01Z						cellular_component											owl:Class	
GO:1990578	biolink:NamedThing	perinuclear endoplasmic reticulum membrane	The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus.	got7fsn_ti	perinuclear ER membrane						mcc	2014-12-09T01:13:01Z						cellular_component											owl:Class	
GO:1901615	biolink:NamedThing	organic hydroxy compound metabolic process	The chemical reactions and pathways involving organic hydroxy compound.	got7fsn_ti	organic hydroxy compound metabolism						pr	2012-11-13T12:54:27Z						biological_process											owl:Class	
GO:0106036	biolink:NamedThing	assembly of apicomedial cortex actomyosin	A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin.	got7fsn_ti							hjd	2017-07-12T16:57:06Z						biological_process											owl:Class	
GO:0000475	biolink:NamedThing	maturation of 2S rRNA	Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0035302	biolink:NamedThing	ecdysteroid 25-hydroxylase activity	Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.	got7fsn_ti					Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22,25-trideoxyecdysone (3-beta,5-beta-ketodiol) to 2,22-dideoxyecdysone (3-beta,5-beta-ketotriol).									molecular_function											owl:Class	
GO:0015488	biolink:NamedThing	glucuronide:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).	got7fsn_ti	glucuronide:monovalent cation symporter activity|glucuronoside permease activity													molecular_function											owl:Class	
GO:0015164	biolink:NamedThing	glucuronoside transmembrane transporter activity	Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.	got7fsn_ti	glucuronide transporter activity													molecular_function											owl:Class	
GO:0035666	biolink:NamedThing	TRIF-dependent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	got7fsn_ti	TRIF-dependent TLR signaling pathway|Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR signaling pathway|TRIF-dependent toll-like receptor signalling pathway						bf	2011-02-01T02:35:35Z						biological_process											owl:Class	
GO:0002756	biolink:NamedThing	MyD88-independent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	got7fsn_ti	MyD88-independent TLR signaling pathway|MyD88-independent toll-like receptor signalling pathway													biological_process											owl:Class	
GO:0030286	biolink:NamedThing	dynein complex	Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0018243	biolink:NamedThing	protein O-linked glycosylation via threonine	The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine.	got7fsn_ti	protein amino acid O-linked glycosylation via threonine											RESID:AA0155		biological_process											owl:Class	
GO:0006493	biolink:NamedThing	protein O-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.	got7fsn_ti	protein amino acid O-linked glycosylation											RESID:AA0154|RESID:AA0153|RESID:AA0212|RESID:AA0155|RESID:AA0157		biological_process											owl:Class	
GO:0009030	biolink:NamedThing	thiamine-phosphate kinase activity	Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate.	got7fsn_ti	thiamin phosphate kinase activity|ATP:thiamine-phosphate phosphotransferase activity|thiamin-phosphate kinase activity|thiamin monophosphokinase activity|thiamin-monophosphate kinase activity|thiamine-monophosphate kinase activity|thiamin monophosphatase activity											MetaCyc:THI-P-KIN-RXN|EC:2.7.4.16|RHEA:15913|KEGG_REACTION:R00617		molecular_function											owl:Class	
GO:0001922	biolink:NamedThing	B-1 B cell homeostasis	The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.	got7fsn_ti	B-1 B-cell homeostasis|B-1 B lymphocyte homeostasis|B-1 B-lymphocyte homeostasis				Note that this term represents the return of B-1 B cell levels to stable numbers following an immune response, as well as the proliferation and elimination of B-1 B cells in a organism required to maintain stable numbers in the absence of an outside stimulus.									biological_process											owl:Class	
GO:0001782	biolink:NamedThing	B cell homeostasis	The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti	B-lymphocyte homeostasis|B lymphocyte homeostasis|B-cell homeostasis				Note that this term represents the return of B cell levels to stable numbers following an immune response as well as the proliferation and elimination of B cells required to maintain stable numbers in the absence of an outside stimulus.									biological_process											owl:Class	
GO:0035301	biolink:NamedThing	Hedgehog signaling complex	A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila).	got7fsn_ti	Hedgehog signalling complex|HSC													cellular_component											owl:Class	
GO:0044273	biolink:NamedThing	sulfur compound catabolic process	The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.	got7fsn_ti	sulfur catabolism|sulfur compound degradation|sulfur compound breakdown|sulfur compound catabolism|sulfur catabolic process													biological_process											owl:Class	
GO:0033378	biolink:NamedThing	establishment of protease localization to T cell secretory granule	The directed movement of a protease to a location within a secretory granule in a T cell.	got7fsn_ti	establishment of protease localization in T cell secretory granule|establishment of protease localization in T lymphocyte secretory granule|establishment of protease localisation in T cell secretory granule|establishment of protease localization in T-cell secretory granule|establishment of protease localization in T-lymphocyte secretory granule													biological_process											owl:Class	
GO:0033376	biolink:NamedThing	establishment of protein localization to T cell secretory granule	The directed movement of a protein to a location within a secretory granule in a T cell.	got7fsn_ti	establishment of protein localization in T lymphocyte secretory granule|establishment of protein localisation in T cell secretory granule|establishment of protein localization in T cell secretory granule|establishment of protein localization in T-lymphocyte secretory granule|establishment of protein localization in T-cell secretory granule													biological_process											owl:Class	
GO:0008445	biolink:NamedThing	D-aspartate oxidase activity	Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide.	got7fsn_ti	aspartic oxidase activity|D-aspartic oxidase activity|D-aspartate:oxygen oxidoreductase (deaminating)											MetaCyc:D-ASPARTATE-OXIDASE-RXN|EC:1.4.3.1|RHEA:12512|Reactome:R-HSA-6810076		molecular_function											owl:Class	
GO:0015922	biolink:NamedThing	aspartate oxidase activity	Catalysis of the reaction: aspartate + O2 = iminosuccinate + hydrogen peroxide.	got7fsn_ti														molecular_function											owl:Class	
GO:0030164	biolink:NamedThing	protein denaturation	Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.	got7fsn_ti												Wikipedia:Denaturation#Protein_denaturation		biological_process											owl:Class	
GO:0044257	biolink:NamedThing	cellular protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.	got7fsn_ti	cellular protein breakdown|cellular protein degradation|cellular protein catabolism													biological_process											owl:Class	
GO:0016574	biolink:NamedThing	histone ubiquitination	The modification of histones by addition of ubiquitin groups.	got7fsn_ti	histone ubiquitinylation|histone ubiquitylation													biological_process											owl:Class	
GO:0140325	biolink:NamedThing	negative regulation of protein localization to medial cortex	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex.	got7fsn_ti							pg	2019-04-17T11:58:27Z						biological_process											owl:Class	
GO:1903077	biolink:NamedThing	negative regulation of protein localization to plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.	got7fsn_ti	downregulation of protein localization to plasma membrane|negative regulation of establishment of protein localization to plasma membrane|down regulation of protein targeting to plasma membrane|downregulation of protein localization in plasma membrane|downregulation of protein targeting to plasma membrane|down-regulation of protein localization to plasma membrane|negative regulation of protein-plasma membrane targeting|down regulation of protein localization to plasma membrane|inhibition of protein localization in plasma membrane|down-regulation of protein localisation in plasma membrane|down regulation of protein localisation in plasma membrane|downregulation of protein-plasma membrane targeting|inhibition of protein targeting to plasma membrane|negative regulation of protein localisation in plasma membrane|inhibition of protein-plasma membrane targeting|negative regulation of establishment of protein localisation in plasma membrane|negative regulation of protein localization in plasma membrane|negative regulation of protein targeting to plasma membrane|down-regulation of protein localization in plasma membrane|down-regulation of protein-plasma membrane targeting|inhibition of protein localisation in plasma membrane|negative regulation of establishment of protein localization in plasma membrane|down-regulation of protein targeting to plasma membrane|down regulation of protein-plasma membrane targeting|inhibition of protein localization to plasma membrane|down regulation of protein localization in plasma membrane|downregulation of protein localisation in plasma membrane						tb	2014-05-29T17:10:16Z			GO:0090005|GO:1905964			biological_process											owl:Class	
GO:0047266	biolink:NamedThing	poly(ribitol-phosphate) beta-glucosyltransferase activity	Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.	got7fsn_ti	UDP-glucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity|UDP-D-glucose polyribitol phosphate glucosyl transferase activity|uridine diphosphoglucose-poly(ribitol-phosphate) beta-glucosyltransferase activity|UDP-D-glucose:polyribitol phosphate glucosyl transferase activity|UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity|UDP glucose-poly(ribitol-phosphate) beta-glucosyltransferase activity											EC:2.4.1.53|MetaCyc:2.4.1.53-RXN|RHEA:10068		molecular_function											owl:Class	
GO:0071516	biolink:NamedThing	establishment of imprinting at mating-type locus	The initial formation of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.	got7fsn_ti	mating type determination, establishment of imprinting						mah	2010-01-06T01:16:27Z						biological_process											owl:Class	
GO:0033039	biolink:NamedThing	salty taste receptor activity	Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste.	got7fsn_ti														molecular_function											owl:Class	
GO:0002791	biolink:NamedThing	regulation of peptide secretion	Any process that modulates the frequency, rate, or extent of peptide secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0051046	biolink:NamedThing	regulation of secretion	Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0030143	biolink:NamedThing	COPI-coated inter-Golgi transport vesicle	A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack).	got7fsn_ti	inter-Golgi transport constitutive secretory pathway transport vesicle										GO:0005807	NIF_Subcellular:sao1382918459		cellular_component											owl:Class	
GO:0030133	biolink:NamedThing	transport vesicle	Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.	got7fsn_ti	Golgi-vacuole transport vesicle|Golgi to vacuole transport vesicle|secretory vesicle|constitutive secretory pathway transport vesicle				Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'.							NIF_Subcellular:sao885490876		cellular_component											owl:Class	
GO:0102752	biolink:NamedThing	1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)	Catalysis of the reaction: a glucosylated glycogenin = a glycogen.	got7fsn_ti												MetaCyc:RXN-7669|EC:2.4.1.18		molecular_function											owl:Class	
GO:0009610	biolink:NamedThing	response to symbiotic fungus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism.	got7fsn_ti	response to symbiotic fungi													biological_process											owl:Class	
GO:0009608	biolink:NamedThing	response to symbiont	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	response of host to symbiont													biological_process											owl:Class	
GO:0044283	biolink:NamedThing	small molecule biosynthetic process	The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.	got7fsn_ti	small molecule biosynthesis				Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.		jl	2010-01-26T12:06:49Z						biological_process											owl:Class	
GO:0009058	biolink:NamedThing	biosynthetic process	The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.	got7fsn_ti	formation|anabolism|multicellular organismal biosynthetic process|single-organism biosynthetic process|biosynthesis|synthesis						jl	2012-10-17T15:52:18Z			GO:0044711|GO:0044274	Wikipedia:Anabolism		biological_process											owl:Class	
GO:0072520	biolink:NamedThing	seminiferous tubule development	The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.	got7fsn_ti							mah	2011-01-04T12:50:36Z						biological_process											owl:Class	
GO:2000872	biolink:NamedThing	positive regulation of progesterone secretion	Any process that activates or increases the frequency, rate or extent of progesterone secretion.	got7fsn_ti							bf	2011-07-26T08:51:22Z						biological_process											owl:Class	
GO:0010087	biolink:NamedThing	phloem or xylem histogenesis	The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	vascular tissue development|vascular tissue histogenesis													biological_process											owl:Class	
GO:0062119	biolink:NamedThing	LinE complex	A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.	got7fsn_ti							dph	2019-03-19T14:00:26Z						cellular_component											owl:Class	
GO:0050373	biolink:NamedThing	UDP-arabinose 4-epimerase activity	Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose.	got7fsn_ti	UDP arabinose epimerase activity|UDParabinose 4-epimerase activity|UDP-D-xylose 4-epimerase activity|UDP-D-xylose-4-epimerase activity|uridine diphosphoarabinose epimerase activity|uridine 5'-diphosphate-D-xylose 4-epimerase activity|UDP-L-arabinose 4-epimerase activity											KEGG_REACTION:R01473|MetaCyc:UDP-ARABINOSE-4-EPIMERASE-RXN|EC:5.1.3.5|RHEA:11320		molecular_function											owl:Class	
GO:0102445	biolink:NamedThing	3-methylquercetin 3'-O-methyltransferase activity	Catalysis of the reaction: 3',4',5-trihydroxy-3-methoxyflavon-7-olate + S-adenosyl-L-methionine  <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13930		molecular_function											owl:Class	
GO:0071285	biolink:NamedThing	cellular response to lithium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.	got7fsn_ti							mah	2009-12-10T04:04:13Z						biological_process											owl:Class	
GO:0071248	biolink:NamedThing	cellular response to metal ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.	got7fsn_ti	cellular response to heavy metal|cellular response to metal						mah	2009-12-03T02:46:31Z						biological_process											owl:Class	
GO:0044581	biolink:NamedThing	butyryl-CoA catabolic process to butyrate	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate.	got7fsn_ti	butyryl-CoA catabolism to butyrate						jl	2012-04-19T04:29:40Z						biological_process											owl:Class	
GO:0044580	biolink:NamedThing	butyryl-CoA catabolic process	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA.	got7fsn_ti	butyryl-CoA catabolism						jl	2012-04-19T04:28:46Z						biological_process											owl:Class	
GO:0015344	biolink:NamedThing	siderophore uptake transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).	got7fsn_ti	siderochrome-iron (ferrioxamine) uptake transporter|ferrioxamine uptake transmembrane transporter activity|siderophore-iron uptake transmembrane transporter activity													molecular_function											owl:Class	
GO:0015343	biolink:NamedThing	siderophore transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).	got7fsn_ti	siderophore-iron transporter activity|siderophore-iron transmembrane transporter activity|siderophore transporter activity|iron-siderophore transporter activity|siderochrome-iron transporter activity|siderochrome transporter activity										GO:0042927|GO:0015236|GO:0015237	Reactome:R-HSA-1222597		molecular_function											owl:Class	
GO:1990941	biolink:NamedThing	mitotic spindle kinetochore microtubule	Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation.	got7fsn_ti							vw	2016-04-06T13:31:38Z						cellular_component											owl:Class	
GO:0051718	biolink:NamedThing	DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).	got7fsn_ti	M.BsuRIb|HpaII methylase|M.BsuRIa|HpaII' methylase											Reactome:R-HSA-5334151		molecular_function											owl:Class	
GO:0000409	biolink:NamedThing	regulation of transcription by galactose	Any process involving galactose that modulates the frequency, rate or extent or transcription.	got7fsn_ti														biological_process											owl:Class	
GO:0006355	biolink:NamedThing	regulation of transcription, DNA-templated	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	got7fsn_ti	regulation of transcription, DNA-dependent|regulation of gene-specific transcription|regulation of cellular transcription, DNA-dependent|transcriptional control										GO:0045449|GO:0032583|GO:0061019			biological_process											owl:Class	
GO:0106281	biolink:NamedThing	chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity	Catalysis of the reaction: chenodeoxycholate + NAD(+) = 7-oxolithocholate + H(+) + NADH.	got7fsn_ti							hjd	2020-07-29T17:48:25Z				RHEA:42036		molecular_function											owl:Class	
GO:1903302	biolink:NamedThing	regulation of pyruvate kinase activity	Any process that modulates the frequency, rate or extent of pyruvate kinase activity.	got7fsn_ti	regulation of phosphoenolpyruvate kinase activity|regulation of phosphoenol transphosphorylase activity|regulation of ATP:pyruvate 2-O-phosphotransferase activity						mr	2014-08-15T23:25:51Z						biological_process											owl:Class	
GO:0051338	biolink:NamedThing	regulation of transferase activity	Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.	got7fsn_ti	transferase regulator				This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.									biological_process											owl:Class	
GO:0060951	biolink:NamedThing	neural crest-derived cardiac glial cell differentiation	The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.	got7fsn_ti							dph	2009-09-29T03:08:06Z						biological_process											owl:Class	
GO:0060950	biolink:NamedThing	cardiac glial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.	got7fsn_ti							dph	2009-09-29T03:06:37Z						biological_process											owl:Class	
GO:0097074	biolink:NamedThing	interferon regulatory factor 7 complex	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 7.	got7fsn_ti	IRF7:IRF7 complex						pr	2011-06-15T04:31:04Z						cellular_component											owl:Class	
GO:0097071	biolink:NamedThing	interferon regulatory factor complex	A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.	got7fsn_ti	IRF complex						pr	2011-06-15T04:22:30Z						cellular_component											owl:Class	
GO:0071499	biolink:NamedThing	cellular response to laminar fluid shear stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers.	got7fsn_ti							mah	2009-12-18T02:43:02Z						biological_process											owl:Class	
GO:0071498	biolink:NamedThing	cellular response to fluid shear stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.	got7fsn_ti							mah	2009-12-18T02:41:44Z						biological_process											owl:Class	
GO:0001947	biolink:NamedThing	heart looping	The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.	got7fsn_ti	cardiac looping													biological_process											owl:Class	
GO:0003143	biolink:NamedThing	embryonic heart tube morphogenesis	The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.	got7fsn_ti							tb	2009-09-22T04:21:17Z						biological_process											owl:Class	
GO:0010020	biolink:NamedThing	chloroplast fission	The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis.	got7fsn_ti	chloroplast division													biological_process											owl:Class	
GO:0009658	biolink:NamedThing	chloroplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.	got7fsn_ti	chloroplast organisation|chloroplast organization and biogenesis													biological_process											owl:Class	
GO:0018163	biolink:NamedThing	protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine.	got7fsn_ti	DNA-protein covalent cross-linking via the 5' end to peptidyl-tyrosine											RESID:AA0254		biological_process											owl:Class	
GO:0045327	biolink:NamedThing	protein-DNA covalent cross-linking via peptidyl-tyrosine	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue.	got7fsn_ti	DNA-protein covalent cross-linking via peptidyl-tyrosine													biological_process											owl:Class	
GO:0000433	biolink:NamedThing	carbon catabolite repression of transcription from RNA polymerase II promoter by glucose	A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.	got7fsn_ti	down regulation of transcription from RNA polymerase II promoter by glucose|inhibition of transcription from RNA polymerase II promoter by glucose|down-regulation of transcription from RNA polymerase II promoter by glucose|downregulation of transcription from RNA polymerase II promoter by glucose													biological_process											owl:Class	
GO:0045014	biolink:NamedThing	carbon catabolite repression of transcription by glucose	A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.	got7fsn_ti	inhibition of transcription by glucose|down-regulation of transcription by glucose|downregulation of transcription by glucose|glucose effect|down regulation of transcription by glucose|glucose repression													biological_process											owl:Class	
GO:0035293	biolink:NamedThing	chitin-based larval cuticle pattern formation	The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0035017	biolink:NamedThing	cuticle pattern formation	The regionalization process that gives rise to the patterns of cell differentiation in the cuticle.	got7fsn_ti														biological_process											owl:Class	
GO:0044786	biolink:NamedThing	cell cycle DNA replication	The DNA-dependent DNA replication that takes place as part of the cell cycle.	got7fsn_ti							jl	2013-05-02T15:52:22Z						biological_process											owl:Class	
GO:0006260	biolink:NamedThing	DNA replication	The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.	got7fsn_ti					DNA biosynthesis is only part of this process. See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'.						GO:0055133	Wikipedia:DNA_replication		biological_process											owl:Class	
GO:0017179	biolink:NamedThing	peptidyl-diphthine metabolic process	The chemical reactions and pathways involving peptidyl-diphthine, a modified histidine residue.	got7fsn_ti	peptidyl-diphthine metabolism													biological_process											owl:Class	
GO:0060007	biolink:NamedThing	linear vestibuloocular reflex	A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.	got7fsn_ti														biological_process											owl:Class	
GO:0060005	biolink:NamedThing	vestibular reflex	A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.	got7fsn_ti														biological_process											owl:Class	
GO:0071670	biolink:NamedThing	smooth muscle cell chemotaxis	The directed movement of a smooth muscle cell in response to an external stimulus.	got7fsn_ti							mah	2010-02-16T01:32:59Z						biological_process											owl:Class	
GO:0018537	biolink:NamedThing	coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity	Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420.	got7fsn_ti	methylenetetrahydromethanopterin reductase activity|N(5),N(10)-methylenetetrahydromethanopterin reductase activity|N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|methylene-H4MPT reductase activity|N5,N10-methylenetetrahydromethanopterin reductase activity|5,10-methylenetetrahydromethanopterin cyclohydrolase activity|5-methyltetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase activity|5,10-methylenetetrahydromethanopterin reductase activity|methylene-H(4)MPT reductase activity											KEGG_REACTION:R04464|UM-BBD_reactionID:r0354|RHEA:21144|EC:1.5.98.2|MetaCyc:METHELENE-THMPT-OXI-RXN		molecular_function											owl:Class	
GO:0042994	biolink:NamedThing	cytoplasmic sequestering of transcription factor	The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.	got7fsn_ti	transcription factor binding, cytoplasmic sequestering|cytoplasmic storage of transcription factor|sequestration of transcription factor in cytoplasm|sequestering of transcription factor in cytoplasm|retention of transcription factor in cytoplasm|storage of transcription factor in cytoplasm|cytoplasmic retention of transcription factor|maintenance of transcription factor protein location in cytoplasm|cytoplasmic sequestration of transcription factor													biological_process											owl:Class	
GO:0044683	biolink:NamedThing	methylthiol:coenzyme M methyltransferase activity	Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM.	got7fsn_ti	methylthiol:coenzyme M methyl transferase activity				This reaction is achieved by the catalysis of two successive steps carried out by the same enzyme - the transfer of a methyl group from the substrate to the cobalt cofactor of a methylated-thiol-specific corrinoid protein (MtsB), and the subsequent transfer of the methyl group from the corrinoid protein to coenzyme M. With most other methanogenesis substrates this process is carried out by two different enzymes (for example, EC:2.1.1.90, methanol-corrinoid protein Co-methyltransferase, and EC:2.1.1.246, methylated methanol-specific corrinoid protein:coenzyme M methyltransferase). The cobalt is oxidized during methylation from the Co(I) state to the Co(III) state, and is reduced back to the Co(I) form during demethylation.		jl	2012-08-15T11:41:24Z				EC:2.1.1.251|MetaCyc:RXN-8125|RHEA:32667		molecular_function											owl:Class	
GO:0060321	biolink:NamedThing	acceptance of pollen	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the acceptance of pollen by cells in the stigma.	got7fsn_ti	acceptance of self pollen|acceptance of non-self pollen													biological_process											owl:Class	
GO:0048544	biolink:NamedThing	recognition of pollen	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the recognition or rejection of the self pollen by cells in the stigma. This process ensures out-breeding in certain plant species.	got7fsn_ti	self incompatibility|recognition or rejection of self pollen|pollen recognition										GO:0009857			biological_process											owl:Class	
GO:0060889	biolink:NamedThing	limb basal epidermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis.	got7fsn_ti							dph	2009-08-13T01:22:12Z						biological_process											owl:Class	
GO:0009913	biolink:NamedThing	epidermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.	got7fsn_ti	hypodermal cell differentiation										GO:0043355			biological_process											owl:Class	
GO:0048892	biolink:NamedThing	lateral line nerve development	The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.	got7fsn_ti	nLL development													biological_process											owl:Class	
GO:0071554	biolink:NamedThing	cell wall organization or biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.	got7fsn_ti	cellular cell wall organization or biogenesis|cell wall organization or biogenesis at cellular level|cellular cell wall organisation or biogenesis|cell wall organisation or biogenesis						mah	2010-01-13T03:19:38Z			GO:0070882			biological_process											owl:Class	
GO:0102209	biolink:NamedThing	trans-permethrin hydrolase activity	Catalysis of the reaction: (-)-trans-permethrin + H2O <=> H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate.	got7fsn_ti												MetaCyc:RXN-12167|RHEA:30283|EC:3.1.1.88		molecular_function											owl:Class	
GO:1903575	biolink:NamedThing	cornified envelope assembly	The aggregation, arrangement and bonding together of a set of components to form a cornified envelope.	got7fsn_ti	cornified envelope formation				An example of this is syntaxin 4 in PMID:22226963.		pr	2014-10-28T10:22:49Z						biological_process											owl:Class	
GO:0071709	biolink:NamedThing	membrane assembly	The aggregation, arrangement and bonding together of a set of components to form a membrane.	got7fsn_ti							mah	2010-03-10T11:19:17Z						biological_process											owl:Class	
GO:0050361	biolink:NamedThing	tryptophan 2-monooxygenase activity	Catalysis of the reaction: L-tryptophan + O(2) = CO(2) + H(2)O + indole-3-acetamide.	got7fsn_ti	L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)											RHEA:16165|KEGG_REACTION:R00679|MetaCyc:TRYPTOPHAN-2-MONOOXYGENASE-RXN|EC:1.13.12.3		molecular_function											owl:Class	
GO:0016703	biolink:NamedThing	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor.	got7fsn_ti												EC:1.13.12.-		molecular_function											owl:Class	
GO:0019866	biolink:NamedThing	organelle inner membrane	The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.	got7fsn_ti					See also the cellular component term 'outer membrane ; GO:0019867'.									cellular_component											owl:Class	
GO:0031090	biolink:NamedThing	organelle membrane	A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.	got7fsn_ti	intracellular membrane											NIF_Subcellular:sao830981606		cellular_component											owl:Class	
GO:0070477	biolink:NamedThing	endospore core	An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.	got7fsn_ti														cellular_component											owl:Class	
GO:0018892	biolink:NamedThing	cyclohexylsulfamate metabolic process	The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide.	got7fsn_ti	cyclohexylsulfamate metabolism|cyclohexylsulphamate metabolic process|cyclohexylsulphamate metabolism											UM-BBD_pathwayID:chs		biological_process											owl:Class	
GO:0021833	biolink:NamedThing	cell-matrix adhesion involved in tangential migration using cell-cell interactions	The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0031589	biolink:NamedThing	cell-substrate adhesion	The attachment of a cell to the underlying substrate via adhesion molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0061255	biolink:NamedThing	mesonephric glomerular parietal epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.	got7fsn_ti							dph	2010-08-30T01:33:52Z						biological_process											owl:Class	
GO:0000225	biolink:NamedThing	N-acetylglucosaminylphosphatidylinositol deacetylase activity	Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.	got7fsn_ti	acetylglucosaminylphosphatidylinositol deacetylase activity|GlcNAc-PI deacetylase activity|N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity|N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity|6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity|GlcNAc-PI de-N-acetylase activity				Note that this function was formerly EC:3.1.1.69.							EC:3.5.1.89|MetaCyc:3.1.1.69-RXN|Reactome:R-HSA-162857|RHEA:11660		molecular_function											owl:Class	
GO:0102386	biolink:NamedThing	phenylacetaldehyde reductase activity	Catalysis of the reaction: 2-phenylethanol + NADP = phenylacetaldehyde + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13536		molecular_function											owl:Class	
GO:0036180	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to biotic stimulus	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.	got7fsn_ti							bf	2012-03-30T04:12:40Z						biological_process											owl:Class	
GO:0044182	biolink:NamedThing	filamentous growth of a population of unicellular organisms	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.	got7fsn_ti							jl	2009-09-25T10:18:32Z						biological_process											owl:Class	
GO:0005726	biolink:NamedThing	perichromatin fibrils	Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts.	got7fsn_ti														cellular_component											owl:Class	
GO:0033829	biolink:NamedThing	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor.	got7fsn_ti	O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase activity|UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase activity											Reactome:R-HSA-5096538|MetaCyc:2.4.1.222-RXN|EC:2.4.1.222|Reactome:R-HSA-1912355		molecular_function											owl:Class	
GO:0035263	biolink:NamedThing	genital disc sexually dimorphic development	The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed.	got7fsn_ti														biological_process											owl:Class	
GO:0055119	biolink:NamedThing	relaxation of cardiac muscle	The process in which the extent of cardiac muscle contraction is reduced.	got7fsn_ti														biological_process											owl:Class	
GO:0090075	biolink:NamedThing	relaxation of muscle	A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.	got7fsn_ti							tb	2009-09-11T11:43:38Z						biological_process											owl:Class	
GO:0042589	biolink:NamedThing	zymogen granule membrane	The lipid bilayer surrounding a zymogen granule.	got7fsn_ti														cellular_component											owl:Class	
GO:0048458	biolink:NamedThing	floral whorl formation	The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti											GO:0048415			biological_process											owl:Class	
GO:0140512	biolink:NamedThing	mitotic nuclear bridge midzone	The central region of a mitotic nuclear bridge, distal to the main portions of the daughter nuclei.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19946|https://github.com/geneontology/go-ontology/issues/20526					pg	2020-09-07T10:08:02Z						cellular_component											owl:Class	
GO:0003912	biolink:NamedThing	DNA nucleotidylexotransferase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).	got7fsn_ti	TdT|nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|terminal deoxynucleotidyltransferase activity|terminal deoxynucleotide transferase activity|deoxyribonucleic nucleotidyltransferase activity|addase activity|terminal transferase activity|terminal addition enzyme activity|terminal deoxyribonucleotidyltransferase activity|deoxynucleotidyl terminal transferase activity|deoxyribonucleic acid nucleotidyltransferase activity											EC:2.7.7.31|MetaCyc:DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0043814	biolink:NamedThing	phospholactate guanylyltransferase activity	Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate.	got7fsn_ti												RHEA:30519|EC:2.7.7.68|MetaCyc:RXN-8077		molecular_function											owl:Class	
GO:0070568	biolink:NamedThing	guanylyltransferase activity	Catalysis of the transfer of a guanylyl group to an acceptor.	got7fsn_ti							mah	2009-04-15T11:05:47Z						molecular_function											owl:Class	
GO:0044326	biolink:NamedThing	dendritic spine neck	Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine.	got7fsn_ti	pedicle|spine neck|neck						jl	2010-08-18T02:31:15Z				NIF_Subcellular:sao1642908940		cellular_component											owl:Class	
GO:1990838	biolink:NamedThing	poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends	Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P).	got7fsn_ti							al	2015-08-26T10:24:51Z						molecular_function											owl:Class	
GO:0000175	biolink:NamedThing	3'-5'-exoribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.	got7fsn_ti	3'-5' exoribonuclease activity											Reactome:R-HSA-6791227|Reactome:R-HSA-9682603|EC:3.1.13.-|Reactome:R-HSA-9694632|Reactome:R-HSA-6791222|Reactome:R-HSA-430028		molecular_function											owl:Class	
GO:0018505	biolink:NamedThing	cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.	got7fsn_ti	cis-dihydrodiol naphthalene dehydrogenase activity|cis-naphthalene dihydrodiol dehydrogenase activity|(+)-cis-naphthalene dihydrodiol dehydrogenase activity|1,2-dihydroxy-1,2-dihydroxynaphthalene dehydrogenase activity|cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase activity|naphthalene dihydrodiol dehydrogenase activity											MetaCyc:1.3.1.29-RXN|EC:1.3.1.29|UM-BBD_enzymeID:e0122|RHEA:11832		molecular_function											owl:Class	
GO:0000179	biolink:NamedThing	rRNA (adenine-N6,N6-)-dimethyltransferase activity	Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.	got7fsn_ti	dimethyladenosine transferase activity|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity|18S rRNA dimethylase activity	https://github.com/geneontology/go-ontology/issues/14459									GO:0043790	Reactome:R-HSA-6790994|Reactome:R-HSA-6793066		molecular_function											owl:Class	
GO:1990831	biolink:NamedThing	cellular response to carcinoembryonic antigen	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins.	got7fsn_ti	cellular response to pregnancy specific glycoprotein						sl	2015-08-20T19:43:12Z						biological_process											owl:Class	
GO:1904588	biolink:NamedThing	cellular response to glycoprotein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.	got7fsn_ti	cellular response to glycoproteins						sl	2015-08-20T16:46:30Z						biological_process											owl:Class	
GO:0010589	biolink:NamedThing	leaf proximal/distal pattern formation	The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis.	got7fsn_ti														biological_process											owl:Class	
GO:0009954	biolink:NamedThing	proximal/distal pattern formation	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).	got7fsn_ti	proximal/distal pattern specification													biological_process											owl:Class	
GO:0034700	biolink:NamedThing	allulose 6-phosphate 3-epimerase activity	Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate.	got7fsn_ti												MetaCyc:RXN0-304|RHEA:28426		molecular_function											owl:Class	
GO:0030559	biolink:NamedThing	rRNA pseudouridylation guide activity	Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0071742	biolink:NamedThing	IgE immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti					Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:1900576	biolink:NamedThing	gerfelin metabolic process	The chemical reactions and pathways involving gerfelin.	got7fsn_ti	gerfelin metabolism						di	2012-05-15T06:42:19Z						biological_process											owl:Class	
GO:0031048	biolink:NamedThing	heterochromatin assembly by small RNA	Assembly of heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.	got7fsn_ti	chromatin silencing by small RNA|heterochromatin formation involved in chromatin silencing by small RNA|RNA-mediated TGS|heterochromatin assembly involved in chromatin silencing by small RNA|RNAi-directed chromatin silencing|RNA-mediated chromatin silencing|small RNA-mediated heterochromatin formation|RNAi-like chromatin silencing|small RNA-mediated heterochromatic silencing|RNA-mediated transcriptional silencing|RNA interference-like chromatin silencing						mah	2009-09-11T04:10:51Z			GO:0070924			biological_process											owl:Class	
GO:0051614	biolink:NamedThing	inhibition of serotonin uptake	Any process that prevents the activation of the directed movement of serotonin into a cell.	got7fsn_ti	inhibition of serotonin import|inhibition of 5-HT uptake|inhibition of 5-hydroxytryptamine uptake|inhibition of 5HT uptake													biological_process											owl:Class	
GO:0051609	biolink:NamedThing	inhibition of neurotransmitter uptake	Any process that prevents the activation of the directed movement of a neurotransmitter into a cell.	got7fsn_ti	inhibition of neurotransmitter import													biological_process											owl:Class	
GO:0003254	biolink:NamedThing	regulation of membrane depolarization	Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.	got7fsn_ti							tb	2009-10-14T10:54:09Z						biological_process											owl:Class	
GO:0014806	biolink:NamedThing	smooth muscle hyperplasia	A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ.	got7fsn_ti														biological_process											owl:Class	
GO:0034322	biolink:NamedThing	alcohol O-decanoyltransferase activity	Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester.	got7fsn_ti														molecular_function											owl:Class	
GO:0051222	biolink:NamedThing	positive regulation of protein transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	upregulation of protein transport|up-regulation of protein transport|activation of protein transport|stimulation of protein transport|up regulation of protein transport													biological_process											owl:Class	
GO:0051050	biolink:NamedThing	positive regulation of transport	Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	up-regulation of transport|stimulation of transport|upregulation of transport|activation of transport|up regulation of transport													biological_process											owl:Class	
GO:0051373	biolink:NamedThing	FATZ binding	Binding to a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components.	got7fsn_ti	filamin-, actinin- and telethonin-binding protein of the Z-disc of striated muscle|FATZ 2 binding|calsarcin 3 binding|calsarcin binding|calsarcin 2 binding|FATZ 1 binding|FATZ 3 binding|calsarcin 1 binding										GO:0051374|GO:0051376|GO:0051375			molecular_function											owl:Class	
GO:0071859	biolink:NamedThing	neuropeptide F receptor binding	Binding to a neuropeptide F receptor.	got7fsn_ti							mah	2010-09-10T03:23:56Z						molecular_function											owl:Class	
GO:0031319	biolink:NamedThing	detection of cAMP	The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP.	got7fsn_ti	detection of 3',5' cAMP|detection of cyclic AMP|cAMP detection|cyclic AMP detection|3',5'-cAMP sensing|detection of adenosine 3',5'-cyclophosphate|3',5'-cAMP detection|cAMP sensing|detection of 3',5'-cAMP													biological_process											owl:Class	
GO:0102197	biolink:NamedThing	vinylacetate caboxylester hydrolase activity	Catalysis of the reaction: but-3-enoate + H2O <=> allyl alcohol + formate.	got7fsn_ti												MetaCyc:RXN-12087		molecular_function											owl:Class	
GO:0010472	biolink:NamedThing	GDP-galactose:glucose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: GDP-L-galactose + alpha-D-glucose 1-phosphate = alpha-L-galactose-1-phosphate + GDP-alpha-D-glucose.	got7fsn_ti	GDP-L-galactose phosphorylase activity|GDP-L-galactose:glucose-1-phosphate guanylyltransferase activity											MetaCyc:RXN4FS-13		molecular_function											owl:Class	
GO:0061375	biolink:NamedThing	mammillotectal axonal tract development	The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.	got7fsn_ti							dph	2010-11-09T09:01:14Z						biological_process											owl:Class	
GO:0034773	biolink:NamedThing	histone H4-K20 trimethylation	The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone.	got7fsn_ti	histone H4 K20 trimethylation|histone lysine H4 K20 trimethylation													biological_process											owl:Class	
GO:0018023	biolink:NamedThing	peptidyl-lysine trimethylation	The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.	got7fsn_ti												RESID:AA0074		biological_process											owl:Class	
GO:0061546	biolink:NamedThing	tyramine secretion, neurotransmission	The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-25T09:16:47Z						biological_process											owl:Class	
GO:0061532	biolink:NamedThing	primary amine secretion, neurotransmission	The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-21T15:57:12Z						biological_process											owl:Class	
GO:0080009	biolink:NamedThing	mRNA methylation	The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0007131	biolink:NamedThing	reciprocal meiotic recombination	The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.	got7fsn_ti	female meiotic recombination|gene conversion with reciprocal crossover										GO:0000021|GO:0007145			biological_process											owl:Class	
GO:0090694	biolink:NamedThing	Scc2-Scc4 cohesin loading complex	A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA.	got7fsn_ti	Mis4-Ssl3 cohesin loading complex						tb	2016-08-24T17:09:11Z						cellular_component											owl:Class	
GO:0032116	biolink:NamedThing	SMC loading complex	A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved.	got7fsn_ti	cohesin loading complex|SCC2/SCC4 loading complex|chromatin loading complex													cellular_component											owl:Class	
GO:0032511	biolink:NamedThing	late endosome to vacuole transport via multivesicular body sorting pathway	The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole.	got7fsn_ti	endosome to vacuole transport via MVB sorting pathway													biological_process											owl:Class	
GO:0032509	biolink:NamedThing	endosome transport via multivesicular body sorting pathway	The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.	got7fsn_ti	endosome transport via MVB sorting pathway													biological_process											owl:Class	
GO:0016939	biolink:NamedThing	kinesin II complex	A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes.	got7fsn_ti														cellular_component											owl:Class	
GO:0005300	biolink:NamedThing	high-affinity tryptophan transmembrane transporter activity	Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high-affinity tryptophan transporter activity													molecular_function											owl:Class	
GO:0015196	biolink:NamedThing	L-tryptophan transmembrane transporter activity	Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.	got7fsn_ti	L-tryptophan transporter activity|L-tryptophan permease activity|valine/tyrosine/tryptophan permease activity										GO:0005299	Reactome:R-HSA-8870352		molecular_function											owl:Class	
GO:0031640	biolink:NamedThing	killing of cells of other organism	Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.	got7fsn_ti	killing of cells of another, non-host, organism|killing of cells of another organism										GO:0001908			biological_process											owl:Class	
GO:0001906	biolink:NamedThing	cell killing	Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.	got7fsn_ti	necrosis													biological_process											owl:Class	
GO:0036350	biolink:NamedThing	mannose-specific flocculation	The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other.	got7fsn_ti	cell-cell adhesion involved in mannose-specific flocculation						bf	2012-09-19T10:57:34Z			GO:0098612			biological_process											owl:Class	
GO:0000128	biolink:NamedThing	flocculation	The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs.	got7fsn_ti	cell-cell adhesion involved in flocculation|coflocculation via lectin-mannose interaction|coflocculation|cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction|flocculation via extracellular polymer|flocculation via cell wall protein-carbohydrate interaction|co-flocculation|coflocculation via protein-carbohydrate interaction	https://github.com/geneontology/go-ontology/issues/18785|https://github.com/geneontology/go-ontology/issues/20192			The word floc derives from the Latin word floccus, which means a tuft of wool.		bf	2012-07-11T01:30:40Z			GO:0000501|GO:0032128|GO:0036282|GO:0036281|GO:0043689|GO:0043690	Wikipedia:Flocculation		biological_process											owl:Class	
GO:0051931	biolink:NamedThing	regulation of sensory perception	Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.	got7fsn_ti														biological_process											owl:Class	
GO:0031644	biolink:NamedThing	regulation of nervous system process	Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.	got7fsn_ti	regulation of neurophysiological process|regulation of neurological process|regulation of neurological system process													biological_process											owl:Class	
GO:0030109	biolink:NamedThing	HLA-B specific inhibitory MHC class I receptor activity	Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.	got7fsn_ti														molecular_function											owl:Class	
GO:0032396	biolink:NamedThing	inhibitory MHC class I receptor activity	Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.	got7fsn_ti														molecular_function											owl:Class	
GO:0007206	biolink:NamedThing	phospholipase C-activating G protein-coupled glutamate receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway|metabotropic glutamate receptor, phospholipase C activating pathway|activation of phospholipase C activity by metabotropic glutamate receptor signalling pathway|activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway|phospholipase C-activating G-protein coupled glutamate receptor signaling pathway													biological_process											owl:Class	
GO:0007216	biolink:NamedThing	G protein-coupled glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	metabotropic glutamate receptor signalling pathway|metabotropic glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway													biological_process											owl:Class	
GO:0060135	biolink:NamedThing	maternal process involved in female pregnancy	A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.	got7fsn_ti														biological_process											owl:Class	
GO:0005766	biolink:NamedThing	primary lysosome	A lysosome before it has fused with a vesicle or vacuole.	got7fsn_ti												NIF_Subcellular:sao1140587416		cellular_component											owl:Class	
GO:0005764	biolink:NamedThing	lysosome	A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.	got7fsn_ti												Wikipedia:Lysosome|NIF_Subcellular:sao585356902		cellular_component											owl:Class	
GO:0060890	biolink:NamedThing	limb spinous cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.	got7fsn_ti							dph	2009-08-13T01:31:30Z						biological_process											owl:Class	
GO:0030216	biolink:NamedThing	keratinocyte differentiation	The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.	got7fsn_ti	keratinocyte cell differentiation													biological_process											owl:Class	
GO:0005980	biolink:NamedThing	glycogen catabolic process	The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.	got7fsn_ti	glycogen catabolism|glycogenolysis|glycogen degradation|glycogen breakdown											MetaCyc:GLYCOCAT-PWY		biological_process											owl:Class	
GO:0016052	biolink:NamedThing	carbohydrate catabolic process	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.	got7fsn_ti	carbohydrate degradation|carbohydrate breakdown|carbohydrate catabolism|single-organism carbohydrate catabolic process|catabolic carbohydrate metabolism|multicellular organismal carbohydrate catabolic process|catabolic carbohydrate metabolic process						jl	2012-10-23T16:34:39Z			GO:0044724|GO:0006095|GO:0044276			biological_process											owl:Class	
GO:0080022	biolink:NamedThing	primary root development	The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle.	got7fsn_ti														biological_process											owl:Class	
GO:0048364	biolink:NamedThing	root development	The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0016719	biolink:NamedThing	carotene 7,8-desaturase activity	Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O.	got7fsn_ti	zeta-carotene desaturase activity|carotene,hydrogen-donor:oxygen oxidoreductase activity											EC:1.3.5.6|RHEA:15701|MetaCyc:1.14.99.30-RXN		molecular_function											owl:Class	
GO:0032999	biolink:NamedThing	Fc-alpha receptor I complex	A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA.	got7fsn_ti	immunoglobulin A receptor complex|FcaRI complex|IgA receptor complex													cellular_component											owl:Class	
GO:0032997	biolink:NamedThing	Fc receptor complex	A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.	got7fsn_ti	immunoglobulin receptor complex|FcR complex|Fc-receptor complex													cellular_component											owl:Class	
GO:0010381	biolink:NamedThing	peroxisome-chloroplast membrane tethering	The attachment of a peroxisome to a chloroplast via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.	got7fsn_ti	attachment of peroxisome to chloroplast													biological_process											owl:Class	
GO:0140056	biolink:NamedThing	organelle localization by membrane tethering	The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.	got7fsn_ti							pg	2017-06-27T09:58:51Z						biological_process											owl:Class	
GO:0002559	biolink:NamedThing	type I hypersensitivity mediated by basophils	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.	got7fsn_ti														biological_process											owl:Class	
GO:0002560	biolink:NamedThing	basophil mediated immunity	Any process involved in the carrying out of an immune response by a basophil.	got7fsn_ti														biological_process											owl:Class	
GO:0010047	biolink:NamedThing	fruit dehiscence	The process leading to the spontaneous opening of the fruit permitting the escape of seeds.	got7fsn_ti														biological_process											owl:Class	
GO:0080060	biolink:NamedThing	integument development	The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex.	got7fsn_ti							dhl	2009-04-13T02:58:07Z						biological_process											owl:Class	
GO:0102194	biolink:NamedThing	protein-fructosamine 3-kinase activity	Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine <=> ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine.	got7fsn_ti	fructosamine-3-kinase activity										GO:0030387	RHEA:59832|MetaCyc:RXN-12005|EC:2.7.1.171		molecular_function											owl:Class	
GO:0005665	biolink:NamedThing	RNA polymerase II, core complex	RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.	got7fsn_ti	RNA polymerase II complex|RNAP II complex|DNA-directed RNA polymerase II, core complex													cellular_component											owl:Class	
GO:0070417	biolink:NamedThing	cellular response to cold	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.	got7fsn_ti	cellular response to cold stress													biological_process											owl:Class	
GO:0009409	biolink:NamedThing	response to cold	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.	got7fsn_ti	freezing tolerance													biological_process											owl:Class	
GO:0035716	biolink:NamedThing	chemokine (C-C motif) ligand 12 binding	Binding to chemokine (C-C motif) ligand 12.	got7fsn_ti	CCL12 binding						bf	2011-03-03T04:25:01Z						molecular_function											owl:Class	
GO:0019957	biolink:NamedThing	C-C chemokine binding	Binding to a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.	got7fsn_ti														molecular_function											owl:Class	
GO:0007503	biolink:NamedThing	fat body development	The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0071471	biolink:NamedThing	cellular response to non-ionic osmotic stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.	got7fsn_ti							mah	2009-12-18T11:47:59Z						biological_process											owl:Class	
GO:0047047	biolink:NamedThing	oxaloglycolate reductase (decarboxylating) activity	Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate.	got7fsn_ti	D-glycerate:NAD(P)+ oxidoreductase (carboxylating)											MetaCyc:1.1.1.92-RXN|EC:1.1.1.92		molecular_function											owl:Class	
GO:0072513	biolink:NamedThing	positive regulation of secondary heart field cardioblast proliferation	Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).	got7fsn_ti	negative regulation of second heart field cardioblast proliferation						mah	2010-12-17T10:16:43Z						biological_process											owl:Class	
GO:0003266	biolink:NamedThing	regulation of secondary heart field cardioblast proliferation	Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).	got7fsn_ti	regulation of SHF cardioblast proliferation|regulation of second heart field cardioblast proliferation						dph	2009-10-15T02:26:15Z						biological_process											owl:Class	
GO:0043920	biolink:NamedThing	aminopropylagmatine ureohydrolase activity	Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea.	got7fsn_ti												EC:3.5.3.24|RHEA:35827		molecular_function											owl:Class	
GO:0006239	biolink:NamedThing	dCMP salvage	Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis.	got7fsn_ti	deoxycytidine monophosphate salvage													biological_process											owl:Class	
GO:0010139	biolink:NamedThing	pyrimidine deoxyribonucleotide salvage	The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis.	got7fsn_ti												MetaCyc:PWY0-181		biological_process											owl:Class	
GO:0044417	biolink:NamedThing	translocation of molecules into host	The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	translocation of molecules into other organism during symbiotic interaction|transport of molecules into other organism during symbiotic interaction|translocation of molecules into other organism involved in symbiotic interaction|transport of molecules into host										GO:0051836			biological_process											owl:Class	
GO:0051701	biolink:NamedThing	biological process involved in interaction with host	An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.	got7fsn_ti	growth of symbiont in host|growth of symbiont in host organelle|growth of symbiont in host cell|growth of symbiont in host vacuole|interaction with host	https://github.com/geneontology/go-ontology/issues/20191									GO:0044125|GO:0044121|GO:0044123|GO:0044119|GO:0044112|GO:0044116|GO:0044117			biological_process											owl:Class	
GO:0004351	biolink:NamedThing	glutamate decarboxylase activity	Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.	got7fsn_ti	L-glutamic decarboxylase activity|aspartic alpha-decarboxylase|L-glutamic acid decarboxylase activity|cysteic acid decarboxylase activity|L-glutamate alpha-decarboxylase activity|L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)|gamma-glutamate decarboxylase activity|L-aspartate-alpha-decarboxylase activity|L-glutamate 1-carboxy-lyase activity											Reactome:R-HSA-888577|EC:4.1.1.15|RHEA:17785|MetaCyc:GLUTDECARBOX-RXN|Reactome:R-HSA-888572		molecular_function											owl:Class	
GO:0140457	biolink:NamedThing	protein demethylase activity	Catalysis of the removal of a methyl group from a protein.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19325					pg	2020-04-23T07:39:14Z						molecular_function											owl:Class	
GO:0014072	biolink:NamedThing	response to isoquinoline alkaloid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.	got7fsn_ti														biological_process											owl:Class	
GO:0014070	biolink:NamedThing	response to organic cyclic compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	got7fsn_ti	response to organic cyclic substance													biological_process											owl:Class	
GO:0034740	biolink:NamedThing	TFIIIC-TOP1-SUB1 complex	A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III.	got7fsn_ti	TFIIIC-Topoisomerase 1-PC4 complex													cellular_component											owl:Class	
GO:0090576	biolink:NamedThing	RNA polymerase III transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III.	got7fsn_ti	RNA polymerase III transcription factor complex						tb	2014-05-09T14:04:37Z						cellular_component											owl:Class	
GO:0051981	biolink:NamedThing	copper chelate transmembrane transporter activity	Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.	got7fsn_ti														molecular_function											owl:Class	
GO:0005375	biolink:NamedThing	copper ion transmembrane transporter activity	Enables the transfer of copper (Cu) ions from one side of a membrane to the other.	got7fsn_ti	copper uptake transmembrane transporter activity|plasma membrane copper transporter|intracellular copper ion transporter										GO:0015088|GO:0005380|GO:0005378|GO:0005379	RHEA:28703|Reactome:R-HSA-437300		molecular_function											owl:Class	
GO:0061193	biolink:NamedThing	taste bud development	The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.	got7fsn_ti							dph	2010-07-27T10:55:08Z						biological_process											owl:Class	
GO:0060516	biolink:NamedThing	primary prostatic bud elongation	The increase in size of the prostatic bud as it forms.	got7fsn_ti	prostate bud elongation|prostate bud elongation involved in prostate morphogenesis													biological_process											owl:Class	
GO:0052200	biolink:NamedThing	response to host defenses	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response to host defense molecules|response of symbiont to host defense molecules|maintenance of symbiont tolerance to host defense molecules	https://github.com/geneontology/go-ontology/issues/18827|https://github.com/geneontology/go-ontology/issues/18951			Note that this term is used to annotate gene products of the symbiont.						GO:0075140|GO:0075145			biological_process											owl:Class	
GO:0033060	biolink:NamedThing	ocellus pigmentation	The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates.	got7fsn_ti														biological_process											owl:Class	
GO:0043473	biolink:NamedThing	pigmentation	The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.	got7fsn_ti														biological_process											owl:Class	
GO:1990922	biolink:NamedThing	hepatic stellate cell proliferation	The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.	got7fsn_ti	Ito cell proliferation|hepatic perisinusoidal cell proliferation|perisinusoidal cell proliferation						sl	2016-01-13T23:12:57Z						biological_process											owl:Class	
GO:0048144	biolink:NamedThing	fibroblast proliferation	The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.	got7fsn_ti														biological_process											owl:Class	
GO:0031234	biolink:NamedThing	extrinsic component of cytoplasmic side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to cytoplasmic side of plasma membrane|extrinsic to internal leaflet of plasma membrane|extrinsic to internal side of plasma membrane				Consider also annotating to 'cell cortex ; GO:0005938'.									cellular_component											owl:Class	
GO:0019897	biolink:NamedThing	extrinsic component of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to plasma membrane|peripheral plasma membrane protein|juxtamembrane										GO:0000157			cellular_component											owl:Class	
GO:0050546	biolink:NamedThing	4-hydroxyphenylpyruvate decarboxylase activity	Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO(2).	got7fsn_ti	4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming)|4-hydroxyphenylpyruvate carboxy-lyase activity											KEGG_REACTION:R03341|RHEA:18697|EC:4.1.1.80|MetaCyc:4.1.1.80-RXN		molecular_function											owl:Class	
GO:0044230	biolink:NamedThing	host cell envelope	An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present.	got7fsn_ti							jl	2009-12-03T03:24:03Z						cellular_component											owl:Class	
GO:0033643	biolink:NamedThing	host cell part	Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									cellular_component											owl:Class	
GO:0018908	biolink:NamedThing	organosulfide cycle	A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle.	got7fsn_ti	organosulphide cycle											UM-BBD_pathwayID:sulf		biological_process											owl:Class	
GO:0006790	biolink:NamedThing	sulfur compound metabolic process	The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.	got7fsn_ti	sulphur metabolic process|sulfur metabolism|sulphur metabolism											Wikipedia:Sulfur_metabolism		biological_process											owl:Class	
GO:0018034	biolink:NamedThing	C-terminal peptidyl-alanine amidation	The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0081		biological_process											owl:Class	
GO:0018033	biolink:NamedThing	protein C-terminal amidation	The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein.	got7fsn_ti														biological_process											owl:Class	
GO:0006066	biolink:NamedThing	alcohol metabolic process	The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.	got7fsn_ti	alcohol metabolism													biological_process											owl:Class	
GO:0047336	biolink:NamedThing	5-methyldeoxycytidine-5'-phosphate kinase activity	Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H(+).	got7fsn_ti	ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase activity											EC:2.7.4.19|KEGG_REACTION:R04235|RHEA:11396|MetaCyc:2.7.4.19-RXN		molecular_function											owl:Class	
GO:0035554	biolink:NamedThing	termination of Roundabout signal transduction	The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated.	got7fsn_ti							bf	2010-05-14T11:08:12Z						biological_process											owl:Class	
GO:0102770	biolink:NamedThing	inositol phosphorylceramide synthase activity	Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol.	got7fsn_ti												MetaCyc:RXN-7795		molecular_function											owl:Class	
GO:0008677	biolink:NamedThing	2-dehydropantoate 2-reductase activity	Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH.	got7fsn_ti	(R)-pantoate:NADP+ 2-oxidoreductase activity|2-ketopantoate reductase activity|2-ketopantoic acid reductase activity|2-oxopantoate reductase activity|ketopantoate reductase activity|ketopantoic acid reductase activity|KPA reductase activity											MetaCyc:2-DEHYDROPANTOATE-REDUCT-RXN|EC:1.1.1.169|RHEA:16233|KEGG_REACTION:R02472		molecular_function											owl:Class	
GO:0006023	biolink:NamedThing	aminoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.	got7fsn_ti	aminoglycan biosynthesis|aminoglycan anabolism|aminoglycan formation|aminoglycan synthesis													biological_process											owl:Class	
GO:0043813	biolink:NamedThing	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate.	got7fsn_ti	phosphatidylinositol 3,5-bisphosphate 5-phosphatase activity											Reactome:R-HSA-1676174|Reactome:R-HSA-1676005|Reactome:R-HSA-1675836|Reactome:R-HSA-1676020		molecular_function											owl:Class	
GO:0048319	biolink:NamedThing	axial mesoderm morphogenesis	The process in which the anatomical structures of the axial mesoderm are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0048332	biolink:NamedThing	mesoderm morphogenesis	The process in which the anatomical structures of the mesoderm are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0052204	biolink:NamedThing	negative regulation of molecular function in other organism involved in symbiotic interaction	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative regulation of protein function in other organism during symbiotic interaction|down regulation of protein function in other organism during symbiotic interaction|inhibition of protein function in other organism during symbiotic interaction|down-regulation of protein function in other organism during symbiotic interaction|inhibition of protein function in other organism|downregulation of protein function in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0044362	biolink:NamedThing	negative regulation of molecular function in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism.	got7fsn_ti							jl	2011-10-27T02:12:49Z						biological_process											owl:Class	
GO:0016207	biolink:NamedThing	4-coumarate-CoA ligase activity	Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.	got7fsn_ti	hydroxycinnamoyl CoA synthetase activity|4-coumarate:CoA ligase activity|4-coumaroyl-CoA synthetase activity|feruloyl coenzyme A synthetase activity|4-coumarate:CoA ligase (AMP-forming)|p-hydroxycinnamoyl coenzyme A synthetase activity|sinapoyl coenzyme A synthetase activity|feruloyl CoA ligase activity|p-coumaryl-CoA ligase activity|p-coumaroyl CoA ligase activity|p-coumaryl-CoA synthetase activity|4-coumarate:coenzyme A ligase activity|4-coumaroyl-CoA synthase activity|hydroxycinnamate:CoA ligase activity|p-coumaryl coenzyme A synthetase activity|caffeolyl coenzyme A synthetase activity|4CL|4-coumaryl-CoA synthetase activity|p-hydroxycinnamic acid:CoA ligase activity|4-coumarate-CoA synthetase activity											KEGG_REACTION:R01616|EC:6.2.1.12|MetaCyc:4-COUMARATE--COA-LIGASE-RXN|RHEA:19641		molecular_function											owl:Class	
GO:0019627	biolink:NamedThing	urea metabolic process	The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.	got7fsn_ti	urea metabolism													biological_process											owl:Class	
GO:0048108	biolink:NamedThing	peptide cross-linking via 4-amino-3-isothiazolidinone	The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue.	got7fsn_ti					Note that this is a generic parent because the identity of the second amino acid is not critical for formation of the cross-link.									biological_process											owl:Class	
GO:0048630	biolink:NamedThing	skeletal muscle tissue growth	The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size.	got7fsn_ti														biological_process											owl:Class	
GO:0097182	biolink:NamedThing	protein C inhibitor-coagulation factor Xa complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa.	got7fsn_ti	plasma serine protease inhibitor-coagulation factor Xa complex|PCI-coagulation factor Xa complex|serpin A5-coagulation factor Xa complex|SERPINA5-coagulation factor Xa complex						pr	2011-10-16T09:01:29Z						cellular_component											owl:Class	
GO:0048834	biolink:NamedThing	specification of petal number	Any process that modulates the number of petals formed in a flower.	got7fsn_ti														biological_process											owl:Class	
GO:0048833	biolink:NamedThing	specification of floral organ number	Any process that modulates the number of floral organs formed in a floral whorl.	got7fsn_ti														biological_process											owl:Class	
GO:0033878	biolink:NamedThing	hormone-sensitive lipase activity	Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate.	got7fsn_ti	HSL|diacylglycerol acylhydrolase activity											MetaCyc:STEROL-ESTERASE-RXN|MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN|EC:3.1.1.79		molecular_function											owl:Class	
GO:0007260	biolink:NamedThing	tyrosine phosphorylation of STAT protein	The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	got7fsn_ti	tyrosine phosphorylation of Stat6 protein|tyrosine phosphorylation of Stat1 protein|tyrosine phosphorylation of Stat4 protein|tyrosine phosphorylation of Stat3 protein|tyrosine phosphorylation of Stat5 protein|tyrosine phosphorylation of Stat7 protein|tyrosine phosphorylation of Stat2 protein										GO:0042505|GO:0042504|GO:0042508|GO:0042507|GO:0042503|GO:0042502|GO:0042506			biological_process											owl:Class	
GO:0018108	biolink:NamedThing	peptidyl-tyrosine phosphorylation	The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.	got7fsn_ti												RESID:AA0039		biological_process											owl:Class	
GO:0033926	biolink:NamedThing	glycopeptide alpha-N-acetylgalactosaminidase activity	Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins.	got7fsn_ti	endo-alpha-acetylgalactosaminidase activity|endo-alpha-N-acetylgalactosaminidase activity|D-galactosyl-N-acetyl-alpha-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase activity											EC:3.2.1.97|MetaCyc:3.2.1.97-RXN		molecular_function											owl:Class	
GO:0102660	biolink:NamedThing	caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity	Catalysis of the reaction: caffeoylshikimate + coenzyme A <=> caffeoyl-CoA + shikimate.	got7fsn_ti												MetaCyc:RXN-2621		molecular_function											owl:Class	
GO:0010492	biolink:NamedThing	maintenance of shoot apical meristem identity	The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0010074	biolink:NamedThing	maintenance of meristem identity	The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	got7fsn_ti	meristem cell maintenance|maintenance of meristem cell identity										GO:0032503			biological_process											owl:Class	
GO:0051987	biolink:NamedThing	positive regulation of attachment of spindle microtubules to kinetochore	Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.	got7fsn_ti	activation of attachment of spindle microtubules to kinetochore|up-regulation of attachment of spindle microtubules to kinetochore|upregulation of attachment of spindle microtubules to kinetochore|stimulation of attachment of spindle microtubules to kinetochore|up regulation of attachment of spindle microtubules to kinetochore													biological_process											owl:Class	
GO:0051984	biolink:NamedThing	positive regulation of chromosome segregation	Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.	got7fsn_ti	up regulation of chromosome segregation|upregulation of chromosome segregation|up-regulation of chromosome segregation|stimulation of chromosome segregation|activation of chromosome segregation													biological_process											owl:Class	
GO:0044808	biolink:NamedThing	oncostatin M production	The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	Oncostatin M production|OSM production						jl	2013-09-11T12:18:00Z						biological_process											owl:Class	
GO:0010287	biolink:NamedThing	plastoglobule	A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.	got7fsn_ti	plastoglobuli|PG										GO:0010502			cellular_component											owl:Class	
GO:0008689	biolink:NamedThing	3-demethylubiquinone-9 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.	got7fsn_ti	5-demethylubiquinone-9 methyltransferase activity|OMHMB-methyltransferase activity|S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase activity|S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase activity											MetaCyc:DHHB-METHYLTRANSFER-RXN|RHEA:17049|EC:2.1.1.64		molecular_function											owl:Class	
GO:0061542	biolink:NamedThing	3-demethylubiquinol-n 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n.	got7fsn_ti	2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase|5-demethylubiquinone-10 methyltransferase|S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase|5-demethylubiquinone-9 methyltransferase|OMHMB-methyltransferase						dph	2013-06-25T08:01:46Z						molecular_function											owl:Class	
GO:0005664	biolink:NamedThing	nuclear origin of replication recognition complex	A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.	got7fsn_ti	eukaryotic ORC|nuclear ORC													cellular_component											owl:Class	
GO:0031981	biolink:NamedThing	nuclear lumen	The volume enclosed by the nuclear inner membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0070013	biolink:NamedThing	intracellular organelle lumen	An organelle lumen that is part of an intracellular organelle.	got7fsn_ti														cellular_component											owl:Class	
GO:0102073	biolink:NamedThing	OPC8-trans-2-enoyl-CoA hydratase activity	Catalysis of the reaction: OPC8-3-hydroxyacyl-CoA <=> OPC8-trans-2-enoyl-CoA + H2O.	got7fsn_ti												MetaCyc:RXN-10697		molecular_function											owl:Class	
GO:0032245	biolink:NamedThing	regulation of purine nucleoside transport	Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0032242	biolink:NamedThing	regulation of nucleoside transport	Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0050234	biolink:NamedThing	pyrazolylalanine synthase activity	Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O.	got7fsn_ti	L-serine hydro-lyase [adding pyrazole; 3-(pyrazol-1-yl)-L-alanine-forming]|beta-pyrazolylalaninase activity|L-serine hydro-lyase (adding pyrazole)											RHEA:24512|EC:4.2.1.50|KEGG_REACTION:R02378|MetaCyc:PYRAZOLYLALANINE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0039651	biolink:NamedThing	induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process	Any process in which a virus increases the frequency, rate or extent of host cysteine-type endopeptidase activity (also called caspase activity) which contributes to the apoptotic process.	got7fsn_ti	activation of host caspases by virus|induction by virus of host caspase activity						bf	2012-10-09T15:44:29Z						biological_process											owl:Class	
GO:0019051	biolink:NamedThing	induction by virus of host apoptotic process	The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions.	got7fsn_ti	activation of apoptosis in host by virus|induction by virus of host apoptotic programmed cell death|activation by virus of host apoptosis|induction by virus of host apoptosis|activation by virus of host apoptotic programmed cell death|induction of apoptosis in host by virus													biological_process											owl:Class	
GO:0098723	biolink:NamedThing	skeletal muscle myofibril	A myofibril of a skeletal muscle fiber.	got7fsn_ti														cellular_component											owl:Class	
GO:0030016	biolink:NamedThing	myofibril	The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.	got7fsn_ti												Wikipedia:Myofibril		cellular_component											owl:Class	
GO:0004978	biolink:NamedThing	corticotropin receptor activity	Combining with corticotropin to initiate a change in cell activity.	got7fsn_ti	adrenocorticotropin receptor activity|ACTH receptor activity|adrenocorticotropic hormone receptor activity													molecular_function											owl:Class	
GO:0004977	biolink:NamedThing	melanocortin receptor activity	Combining with melanocortin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:1904951	biolink:NamedThing	positive regulation of establishment of protein localization	Any process that activates or increases the frequency, rate or extent of establishment of protein localization.	got7fsn_ti	up regulation of protein recruitment|positive regulation of establishment of protein localisation|upregulation of establishment of protein localization|upregulation of protein positioning|up regulation of establishment of protein localization|positive regulation of protein recruitment|up-regulation of establishment of protein localization|activation of protein recruitment|up regulation of establishment of protein localisation|activation of protein positioning|upregulation of protein recruitment|up-regulation of protein positioning|upregulation of establishment of protein localisation|activation of establishment of protein localization|activation of establishment of protein localisation|up regulation of protein positioning|up-regulation of protein recruitment|up-regulation of establishment of protein localisation|positive regulation of protein positioning						mec	2016-02-05T09:59:32Z						biological_process											owl:Class	
GO:0060158	biolink:NamedThing	phospholipase C-activating dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	activation of phospholipase C activity by dopamine receptor signaling pathway|activation of phospholipase C activity by dopamine receptor signalling pathway|dopamine receptor, phospholipase C activating pathway													biological_process											owl:Class	
GO:0007200	biolink:NamedThing	phospholipase C-activating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	phospholipase C-activating dopamine receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|PLC-activating GPCR signaling pathway|G-protein coupled receptor signaling pathway coupled to IP3 second messenger|G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|G protein signalling, coupled to IP3 second messenger (phospholipase C activating)				This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity.									biological_process											owl:Class	
GO:0042389	biolink:NamedThing	omega-3 fatty acid desaturase activity	Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0052430	biolink:NamedThing	modulation by host of symbiont RNA levels	The alteration by an organism of the levels of RNA in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0051851	biolink:NamedThing	modulation by host of symbiont process	The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by host of symbiont morphology or physiology													biological_process											owl:Class	
GO:0052775	biolink:NamedThing	endo-1,3-alpha-L-rhamnosidase activity	Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain.	got7fsn_ti	endorhamnosidase activity|endo-(1,3)-alpha-L-rhamnosidase activity|endo-(1->3)-alpha-L-rhamnosidase activity						ai	2011-10-05T03:30:33Z						molecular_function											owl:Class	
GO:0010944	biolink:NamedThing	negative regulation of transcription by competitive promoter binding	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site.	got7fsn_ti														biological_process											owl:Class	
GO:0090446	biolink:NamedThing	negative regulation of nematode larval development, heterochronic	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.	got7fsn_ti							tb	2012-08-24T13:24:43Z						biological_process											owl:Class	
GO:0090444	biolink:NamedThing	regulation of nematode larval development, heterochronic	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached.	got7fsn_ti							tb	2012-08-24T13:24:43Z						biological_process											owl:Class	
GO:0090650	biolink:NamedThing	cellular response to oxygen-glucose deprivation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.	got7fsn_ti	cellular response to OGD						tb	2015-07-01T10:27:29Z						biological_process											owl:Class	
GO:0036294	biolink:NamedThing	cellular response to decreased oxygen levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.	got7fsn_ti	cellular response to lowered oxygen levels				This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'cellular response to hypoxia ; GO:0071456'.		bf	2012-07-20T01:08:40Z						biological_process											owl:Class	
GO:0102815	biolink:NamedThing	caffeoyl-CoA:delphinidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-caffeoylglucoside + coenzyme A.	got7fsn_ti												MetaCyc:RXN-8233|EC:2.3.1.153		molecular_function											owl:Class	
GO:0005464	biolink:NamedThing	UDP-xylose transmembrane transporter activity	Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.	got7fsn_ti												Reactome:R-HSA-742373		molecular_function											owl:Class	
GO:0015165	biolink:NamedThing	pyrimidine nucleotide-sugar transmembrane transporter activity	Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0003012	biolink:NamedThing	muscle system process	A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.	got7fsn_ti	muscle physiological process													biological_process											owl:Class	
GO:0062167	biolink:NamedThing	complement component C1q complex	A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning.	got7fsn_ti	C1q|Complement 1q						dph	2019-11-12T13:21:57Z						cellular_component											owl:Class	
GO:0006720	biolink:NamedThing	isoprenoid metabolic process	The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	got7fsn_ti	polyterpene metabolism|polyterpene metabolic process|polyisoprenoid metabolic process|polyisoprenoid metabolism|isoprenoid metabolism										GO:0016096			biological_process											owl:Class	
GO:0014848	biolink:NamedThing	urinary tract smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.	got7fsn_ti														biological_process											owl:Class	
GO:0006939	biolink:NamedThing	smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.	got7fsn_ti	visceral muscle contraction													biological_process											owl:Class	
GO:0019843	biolink:NamedThing	rRNA binding	Binding to a ribosomal RNA.	got7fsn_ti	base pairing with rRNA										GO:0000944			molecular_function											owl:Class	
GO:0003723	biolink:NamedThing	RNA binding	Binding to an RNA molecule or a portion thereof.	got7fsn_ti	poly(A) RNA binding|poly(A)-RNA binding|poly-A RNA binding|base pairing with RNA										GO:0000498|GO:0044822	Reactome:R-HSA-203922		molecular_function											owl:Class	
GO:0008999	biolink:NamedThing	ribosomal-protein-alanine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine.	got7fsn_ti	acetyl-CoA:ribosomal-protein-L-alanine N-acetyltransferase activity|ribosomal protein S18 acetyltransferase activity											EC:2.3.1.267|MetaCyc:2.3.1.128-RXN		molecular_function											owl:Class	
GO:0021798	biolink:NamedThing	forebrain dorsal/ventral pattern formation	The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.	got7fsn_ti	forebrain dorsal-ventral pattern formation|forebrain dorsoventral pattern formation													biological_process											owl:Class	
GO:0009953	biolink:NamedThing	dorsal/ventral pattern formation	The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.	got7fsn_ti	dorsoventral pattern formation|dorsal/ventral pattern specification|dorsal-ventral pattern formation													biological_process											owl:Class	
GO:0030566	biolink:NamedThing	snRNA modification guide activity	Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0017069	biolink:NamedThing	snRNA binding	Binding to a small nuclear RNA (snRNA).	got7fsn_ti	small nuclear RNA binding|base pairing with snRNA										GO:0000945			molecular_function											owl:Class	
GO:0075502	biolink:NamedThing	endosome membrane permeabilization involved in viral entry into host cell	Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm.	got7fsn_ti	viral entry into host cell via caveolae-mediated endocytosis followed by endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by endosome membrane permeabilization						jl	2010-06-02T02:40:25Z			GO:0075518			biological_process											owl:Class	
GO:0039665	biolink:NamedThing	permeabilization of host organelle membrane involved in viral entry into host cell	Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm.	got7fsn_ti	viral penetration via permeabilization of host organellar membrane|viral penetration via host endosomal membrane disruption by virus|viral membrane-penetration protein|viral entry into host cell via permeabilization of host organelle membrane|viral penetration via perforation of host organellar membrane by virus						bf	2013-08-29T11:57:21Z				VZ:985		biological_process											owl:Class	
GO:0042766	biolink:NamedThing	nucleosome mobilization	The movement of nucleosomes along a DNA fragment.	got7fsn_ti	nucleosome sliding													biological_process											owl:Class	
GO:0034728	biolink:NamedThing	nucleosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.	got7fsn_ti	nucleosome organisation													biological_process											owl:Class	
GO:0047508	biolink:NamedThing	(R)-2-methylmalate dehydratase activity	Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H(2)O.	got7fsn_ti	(R)-2-methylmalate hydro-lyase activity|citraconate hydratase activity|citraconase activity|citramalate hydro-lyase activity|(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)|(-)-citramalate hydro-lyase activity											MetaCyc:R-2-METHYLMALATE-DEHYDRATASE-RXN|EC:4.2.1.35|RHEA:22332|KEGG_REACTION:R03896		molecular_function											owl:Class	
GO:0102387	biolink:NamedThing	2-phenylethanol acetyltransferase activity	Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A.	got7fsn_ti												EC:2.3.1.224|MetaCyc:RXN-13542		molecular_function											owl:Class	
GO:0036163	biolink:NamedThing	3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity	Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2.	got7fsn_ti							bf	2012-03-26T01:49:54Z				RHEA:44768|KEGG_REACTION:R06866		molecular_function											owl:Class	
GO:0018608	biolink:NamedThing	1-indanone dioxygenase activity	Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone.	got7fsn_ti												EC:1.14.12.-|UM-BBD_reactionID:r0416		molecular_function											owl:Class	
GO:0061762	biolink:NamedThing	CAMKK-AMPK signaling cascade	A series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.	got7fsn_ti	stress-activated AMP-activated protein kinase signaling cascade						dph	2016-04-14T12:59:31Z						biological_process											owl:Class	
GO:0019722	biolink:NamedThing	calcium-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.	got7fsn_ti	calcium ion signaling|calcium signaling|calcium-mediated signalling|calcium signalling											Wikipedia:Calcium_signaling		biological_process											owl:Class	
GO:0052039	biolink:NamedThing	disruption by symbiont of host cytoskeleton	The process in which an organism effects a change that impairs the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by symbiont of host cytoskeleton|rounding by symbiont of host cells										GO:0044054			biological_process											owl:Class	
GO:0002473	biolink:NamedThing	non-professional antigen presenting cell antigen processing and presentation	The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils.	got7fsn_ti														biological_process											owl:Class	
GO:0019177	biolink:NamedThing	dihydroneopterin triphosphate pyrophosphohydrolase activity	Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate.	got7fsn_ti												RHEA:25302|MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN		molecular_function											owl:Class	
GO:0047297	biolink:NamedThing	asparagine-oxo-acid transaminase activity	Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate.	got7fsn_ti	asparagine-oxo-acid aminotransferase activity|L-asparagine:2-oxo-acid aminotransferase activity|asparagine-keto acid aminotransferase activity|asparagine--oxo-acid aminotransferase activity											EC:2.6.1.14|RHEA:19813|MetaCyc:2.6.1.14-RXN		molecular_function											owl:Class	
GO:0102424	biolink:NamedThing	sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity	Catalysis of the reaction: (+)-sesaminol 2-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-gentiotrioside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13821		molecular_function											owl:Class	
GO:0042986	biolink:NamedThing	positive regulation of amyloid precursor protein biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.	got7fsn_ti	upregulation of amyloid precursor protein biosynthetic process|stimulation of amyloid precursor protein biosynthetic process|activation of amyloid precursor protein biosynthetic process|up-regulation of amyloid precursor protein biosynthetic process|positive regulation of APP biosynthesis|positive regulation of amyloid precursor protein biosynthesis|positive regulation of amyloid precursor protein formation|positive regulation of amyloid precursor protein anabolism|up regulation of amyloid precursor protein biosynthetic process|positive regulation of APP biosynthetic process|positive regulation of amyloid precursor protein synthesis													biological_process											owl:Class	
GO:0010560	biolink:NamedThing	positive regulation of glycoprotein biosynthetic process	Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	got7fsn_ti														biological_process											owl:Class	
GO:0044666	biolink:NamedThing	MLL3/4 complex	A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species.	got7fsn_ti	Trr/COMPASS-like complex						jl	2012-08-07T14:46:40Z						cellular_component											owl:Class	
GO:0035097	biolink:NamedThing	histone methyltransferase complex	A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0044569	biolink:NamedThing	[Ni-Fe] hydrogenase complex	A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer.	got7fsn_ti	Ni-Fe hydrogenase complex|nickel-iron hydrogenase complex						jl	2012-04-18T01:26:35Z						cellular_component											owl:Class	
GO:1902494	biolink:NamedThing	catalytic complex	A protein complex which is capable of catalytic activity.	got7fsn_ti	enzyme complex						bhm	2013-11-13T16:18:47Z						cellular_component											owl:Class	
GO:0051823	biolink:NamedThing	regulation of synapse structural plasticity	Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane.	got7fsn_ti	regulation of synaptic structural plasticity													biological_process											owl:Class	
GO:0050807	biolink:NamedThing	regulation of synapse organization	Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).	got7fsn_ti	regulation of synapse organisation|regulation of synapse organization and biogenesis|regulation of synapse structure													biological_process											owl:Class	
GO:0018259	biolink:NamedThing	RNA-protein covalent cross-linking via peptidyl-serine	The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine.	got7fsn_ti												RESID:AA0213		biological_process											owl:Class	
GO:0018144	biolink:NamedThing	RNA-protein covalent cross-linking	The formation of a covalent cross-link between RNA and a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0003091	biolink:NamedThing	renal water homeostasis	Renal process involved in the maintenance of an internal steady state of water in the body.	got7fsn_ti	water homeostasis by the renal system													biological_process											owl:Class	
GO:0004503	biolink:NamedThing	tyrosinase activity	Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates.	got7fsn_ti	pyrocatechol oxidase|chlorogenic oxidase activity|phenolase activity|catecholase|o-diphenol oxidase activity|monophenolase activity|monophenol oxidase activity|L-tyrosine monooxygenase activity|dopa oxidase|tyrosine-dopa oxidase activity|monophenol oxygenase|N-acetyl-6-hydroxytryptophan oxidase activity|prophenoloxidase activity|monophenol monooxygenase activity|o-diphenol:O2 oxidoreductase activity|monophenol monooxidase activity|chlorogenic acid oxidase activity|o-diphenol oxidoreductase|prophenol oxidase activity|phenol oxidase activity|cresolase activity	https://github.com/geneontology/go-ontology/issues/21024#issuecomment-909025243			In mammals, L-DOPA can act as a cofactor for the catalyzed reaction; therefore in some resources L-DOPA is shown on both sides of the reaction. GO:0004503 describes the monooxygenation of the monophenol, L-tyrosine. For oxidation of diphenols (including L-DOPA and dopamine), consider instead the term 'catechol oxidase activity ; GO:0004097' and its children.							EC:1.14.18.1|MetaCyc:MONOPHENOL-MONOOXYGENASE-RXN|RHEA:18117		molecular_function											owl:Class	
GO:0016716	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor.	got7fsn_ti												EC:1.14.18.-		molecular_function											owl:Class	
GO:1904071	biolink:NamedThing	presynaptic active zone assembly	The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone.  The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.	got7fsn_ti	pre-synaptic active zone component formation|pre-synaptic active zone assembly|pre-synaptic active zone component assembly|pre-synaptic active zone formation|presynaptic active zone formation						pr	2015-03-20T10:36:27Z						biological_process											owl:Class	
GO:0085017	biolink:NamedThing	entry into host cell by a symbiont-containing vacuole	The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole.	got7fsn_ti	symbiont entry into host cell forming a symbiont-containing vacuole|symbiont entry into host cell forming a pathogen-containing vacuole|symbiont entry into host cell forming a parasitophorous vacuole						jl	2010-05-20T02:55:34Z			GO:0052370			biological_process											owl:Class	
GO:0044409	biolink:NamedThing	entry into host	Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	invasion of host|other organism cell invasion|entry into host via a specialized structure during symbiotic interaction|invasion of other organism|entry into host cell via penetration peg|penetration into host|entry into host via enzymatic degradation of host anatomical structure|invasion into other organism|entry into host through host barriers|penetration into host via a specialized structure during symbiotic interaction|invasion into host|host penetration|other organism invasion|entry into cell of other organism during symbiotic interaction|entry into other organism involved in symbiotic interaction|penetration into host via a specialized structure|host cell invasion|entry into cell of other organism involved in symbiotic interaction|invasive growth|entry into other organism during symbiotic interaction|host invasion|entry into host via enzymatic degradation of host cuticle|entry into host cell	https://github.com/geneontology/go-ontology/issues/18563									GO:0051830|GO:0085028|GO:0051806|GO:0044411|GO:0085027|GO:0075052|GO:0051828|GO:0030260			biological_process											owl:Class	
GO:0052126	biolink:NamedThing	movement in host environment	The directed movement of an organism or motile cell on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	movement in response to host													biological_process											owl:Class	
GO:0008928	biolink:NamedThing	mannose-1-phosphate guanylyltransferase (GDP) activity	Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate.	got7fsn_ti	GDP-mannose phosphorylase activity|mannose 1-phosphate guanylyltransferase activity|GDP-mannose 1-phosphate guanylyltransferase activity|GDP-mannose pyrophosphorylase activity|GDP:alpha-D-mannose-1-phosphate guanylyltransferase activity|GDP:mannose-1-phosphate guanylyltransferase activity|GDP mannose phosphorylase activity|guanosine diphosphomannose phosphorylase activity|mannose 1-phosphate (guanosine diphosphate) guanylyltransferase activity|guanosine diphosphate-mannose 1-phosphate guanylyltransferase activity|GDP:D-mannose-1-phosphate guanylyltransferase activity											EC:2.7.7.22|KEGG_REACTION:R00883|MetaCyc:MANNPGUANYLTRANGDP-RXN|RHEA:12905		molecular_function											owl:Class	
GO:0008905	biolink:NamedThing	mannose-phosphate guanylyltransferase activity	Catalysis of the transfer of a phosphate group from GTP or GDP to a mannose molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:1900595	biolink:NamedThing	(+)-kotanin catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-kotanin.	got7fsn_ti	(+)-kotanin degradation|(+)-kotanin breakdown|(+)-kotanin catabolism						di	2012-05-15T06:54:40Z						biological_process											owl:Class	
GO:0009252	biolink:NamedThing	peptidoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.	got7fsn_ti	peptidoglycan synthesis|murein biosynthesis|peptidoglycan biosynthesis|murein biosynthetic process|peptidoglycan anabolism|peptidoglycan formation										GO:0009285			biological_process											owl:Class	
GO:0044038	biolink:NamedThing	cell wall macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall.	got7fsn_ti	cell wall macromolecule anabolism|cell wall macromolecule biosynthesis|cell wall macromolecule synthesis|cell wall macromolecule biosynthetic process at cellular level|cellular cell wall macromolecule biosynthetic process													biological_process											owl:Class	
GO:0070087	biolink:NamedThing	chromo shadow domain binding	Binding to a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain.	got7fsn_ti	chromoshadow domain binding													molecular_function											owl:Class	
GO:0072135	biolink:NamedThing	kidney mesenchymal cell proliferation	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney.	got7fsn_ti							mah	2010-02-22T02:33:10Z						biological_process											owl:Class	
GO:0010463	biolink:NamedThing	mesenchymal cell proliferation	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	got7fsn_ti														biological_process											owl:Class	
GO:0051954	biolink:NamedThing	positive regulation of amine transport	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	activation of amine transport|upregulation of amine transport|up-regulation of amine transport|stimulation of amine transport|up regulation of amine transport													biological_process											owl:Class	
GO:0042494	biolink:NamedThing	detection of bacterial lipoprotein	The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs).	got7fsn_ti	detection of Lpp|perception of BLP|detection of BLP|perception of bacterial lipoprotein|perception of Lpp													biological_process											owl:Class	
GO:0032493	biolink:NamedThing	response to bacterial lipoprotein	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0002238	biolink:NamedThing	response to molecule of fungal origin	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.	got7fsn_ti	response to fungus associated molecule													biological_process											owl:Class	
GO:0000077	biolink:NamedThing	DNA damage checkpoint signaling	A signal transduction process that contributes to a DNA damage checkpoint.	got7fsn_ti	DNA damage checkpoint|signal transduction involved in DNA damage checkpoint|DNA damage response, signal transduction resulting in cell cycle arrest						mah	2010-12-08T04:18:11Z			GO:0072422	Wikipedia:DNA_damage_checkpoint|Wikipedia:Postreplication_checkpoint		biological_process											owl:Class	
GO:0042770	biolink:NamedThing	signal transduction in response to DNA damage	A cascade of processes induced by the detection of DNA damage within a cell.	got7fsn_ti	response to DNA damage stimulus by intracellular signaling cascade|DNA damage response, signal transduction													biological_process											owl:Class	
GO:0051600	biolink:NamedThing	regulation of endocytosis by exocyst localization	Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.	got7fsn_ti	regulation of site selection of endocytosis|regulation of endocytosis by exocyst localisation|relocation of endocytosis|spatial regulation of endocytosis													biological_process											owl:Class	
GO:0030100	biolink:NamedThing	regulation of endocytosis	Any process that modulates the frequency, rate or extent of endocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0000812	biolink:NamedThing	Swr1 complex	A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.	got7fsn_ti	SWR-C													cellular_component											owl:Class	
GO:0000118	biolink:NamedThing	histone deacetylase complex	A protein complex that possesses histone deacetylase activity.	got7fsn_ti	HDAC complex				Note that this term represents a location, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone deacetylase activity ; GO:0004407'.									cellular_component											owl:Class	
GO:0004879	biolink:NamedThing	nuclear receptor activity	A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytoplasm, which leads to its tranlocation to the nucleus.	got7fsn_ti	ligand-dependent nuclear receptor activity|nuclear receptor activity|9-cis retinoic acid receptor activity|vitamin D receptor activity|RXR|retinoic acid receptor activity|calcitriol receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|1,25-(OH)2D3 receptor activity|vitamin D3 receptor activity|vitamin A receptor activity|ligand-dependent transcription factor activity|glucocorticoid receptor activity|juvenile hormone receptor activity|ecdysteroid hormone receptor activity|estrogen nuclear receptor activity|thyroid hormone receptor activity|RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding|nuclear hormone receptor|RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding|retinoid-X receptor activity|RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding|androgen receptor activity	https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/19518			Usage guidance: Nuclear receptors are a protein family defined by the presence of a C4-type zinc finger DNA-binding domain and a ligand binding domain. For nuclear receptors, the DNA binding motif is most often referred to as a response element. GO:0004879 is intended for annotation of nuclear receptors that regulate transcription by binding directly to DNA. When the nuclear receptor functions by binding to other transcription factors or transcription factor complexes, consider instead annotating to 'GO:0030374 ; nuclear receptor transcription coactivator activity' or GO:0140536 ; nuclear corepressor activity.						GO:0004886|GO:0008434|GO:0004884|GO:0003708|GO:0004880|GO:0038052|GO:0038051|GO:0004887|GO:0038050|GO:0004882			molecular_function											owl:Class	
GO:0098531	biolink:NamedThing	ligand-activated transcription factor activity	A DNA-binding transcription factor activity regulated by binding to a ligand and that modulates the transcription of specific gene sets. Examples include the lac and trp repressors in E.coli and steroid hormone receptors.	got7fsn_ti	transcription factor activity, direct ligand regulated sequence-specific DNA binding|direct ligand regulated sequence-specific DNA binding transcription factor activity				For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		dos	2013-10-17T15:51:30Z						molecular_function											owl:Class	
GO:1903036	biolink:NamedThing	positive regulation of response to wounding	Any process that activates or increases the frequency, rate or extent of response to wounding.	got7fsn_ti	up-regulation of response to wounding|activation of physiological response to wounding|up regulation of response to wounding|up-regulation of physiological response to wounding|positive regulation of physiological response to wounding|activation of response to wounding|upregulation of physiological response to wounding|upregulation of response to wounding|up regulation of physiological response to wounding						kmv	2014-05-18T01:28:58Z						biological_process											owl:Class	
GO:1903034	biolink:NamedThing	regulation of response to wounding	Any process that modulates the frequency, rate or extent of response to wounding.	got7fsn_ti	regulation of physiological response to wounding						kmv	2014-05-18T01:28:46Z						biological_process											owl:Class	
GO:0051964	biolink:NamedThing	negative regulation of synapse assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.	got7fsn_ti	down regulation of synapse assembly|inhibition of synapse assembly|negative regulation of synapse biogenesis|negative regulation of synaptogenesis|down-regulation of synapse assembly|downregulation of synapse assembly													biological_process											owl:Class	
GO:0051961	biolink:NamedThing	negative regulation of nervous system development	Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.	got7fsn_ti	down regulation of nervous system development|downregulation of nervous system development|down-regulation of nervous system development|inhibition of nervous system development													biological_process											owl:Class	
GO:0033106	biolink:NamedThing	cis-Golgi network membrane	The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network.	got7fsn_ti	Golgi cis face membrane|cis Golgi network membrane													cellular_component											owl:Class	
GO:0140375	biolink:NamedThing	immune receptor activity	Receiving a signal and transmitting it in a cell to initiate an immune response.	got7fsn_ti							pg	2019-10-18T14:11:15Z						molecular_function											owl:Class	
GO:0016520	biolink:NamedThing	growth hormone-releasing hormone receptor activity	Combining with growth hormone-releasing hormone to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0030187	biolink:NamedThing	melatonin biosynthetic process	The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).	got7fsn_ti	melatonin anabolism|melatonin formation|melatonin synthesis|melatonin biosynthesis													biological_process											owl:Class	
GO:0042435	biolink:NamedThing	indole-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton.	got7fsn_ti	indole-containing compound formation|indole derivative biosynthetic process|indole-containing compound anabolism|indole-containing compound synthesis|indole-containing compound biosynthesis|indole derivative biosynthesis													biological_process											owl:Class	
GO:0031827	biolink:NamedThing	type 2B serotonin receptor binding	Binding to a type 2B serotonin receptor.	got7fsn_ti	5-hydroxytryptamine 2B receptor binding|type 2B serotonin receptor ligand													molecular_function											owl:Class	
GO:0031821	biolink:NamedThing	G protein-coupled serotonin receptor binding	Binding to a metabotropic serotonin receptor.	got7fsn_ti	metabotropic 5-hydroxytryptamine receptor binding|metabotropic serotonin receptor ligand|metabotropic serotonin receptor binding|G-protein coupled serotonin receptor binding													molecular_function											owl:Class	
GO:0043697	biolink:NamedThing	cell dedifferentiation	The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.	got7fsn_ti					Note that this term should be used to annotate gene products involved in dedifferentiation that occurs as part of a normal process, such as regeneration. It should not be used for dedifferentiation that occurs in an abnormal or disease state such as cancer.									biological_process											owl:Class	
GO:0043696	biolink:NamedThing	dedifferentiation	The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.	got7fsn_ti												Wikipedia:Cellular_differentiation#Dedifferentiation		biological_process											owl:Class	
GO:0043226	biolink:NamedThing	organelle	Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.	got7fsn_ti												Wikipedia:Organelle|NIF_Subcellular:sao1539965131		cellular_component											owl:Class	
GO:0098629	biolink:NamedThing	trans-Golgi network membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0005340	biolink:NamedThing	nucleotide-sulfate transmembrane transporter activity	Enables the transfer of nucleotide-sulfate from one side of a membrane to the other.	got7fsn_ti	nucleotide-sulphate transporter activity										GO:0005341			molecular_function											owl:Class	
GO:0015116	biolink:NamedThing	sulfate transmembrane transporter activity	Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.	got7fsn_ti	sulphate transporter activity|sulfate permease activity											RHEA:34983|Reactome:R-HSA-427555|Reactome:R-HSA-8875871|Reactome:R-HSA-3560789		molecular_function											owl:Class	
GO:0033803	biolink:NamedThing	kaempferol 4'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide.	got7fsn_ti	S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase activity|S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase activity|F 4'-OMT											RHEA:15105|KEGG_REACTION:R06807|EC:2.1.1.155|MetaCyc:2.1.1.155-RXN		molecular_function											owl:Class	
GO:0008516	biolink:NamedThing	hexose uniporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0015149	biolink:NamedThing	hexose transmembrane transporter activity	Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-189242|Reactome:R-HSA-5638222		molecular_function											owl:Class	
GO:0070051	biolink:NamedThing	fibrinogen binding	Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.	got7fsn_ti														molecular_function											owl:Class	
GO:0002227	biolink:NamedThing	innate immune response in mucosa	Any process of the innate immune response that takes place in the mucosal tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0008715	biolink:NamedThing	CDP-diacylglycerol diphosphatase activity	Catalysis of the reaction: CDP-diacylglycerol + H(2)O = a phosphatidate + CMP + 2 H(+).	got7fsn_ti	CDP-diacylglycerol phosphatidylhydrolase activity|CDP-diacylglycerol pyrophosphatase activity|CDP diacylglycerol hydrolase activity|cytidine diphosphodiacylglycerol pyrophosphatase activity											EC:3.6.1.26|KEGG_REACTION:R01797|MetaCyc:CDPDIGLYPYPHOSPHA-RXN|RHEA:15221		molecular_function											owl:Class	
GO:0036189	biolink:NamedThing	abieta-7,13-diene hydroxylase activity	Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O.	got7fsn_ti	abietadiene hydroxylase						bf	2012-04-19T10:57:05Z				MetaCyc:RXN-8507|KEGG_REACTION:R06351|EC:1.14.14.144|RHEA:26217		molecular_function											owl:Class	
GO:0061596	biolink:NamedThing	3-sulfolactaldehyde reductase activity	Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.	got7fsn_ti							dph	2014-02-10T10:09:43Z				RHEA:40511|EC:1.1.1.373|MetaCyc:RXN-15299		molecular_function											owl:Class	
GO:0060293	biolink:NamedThing	germ plasm	Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.	got7fsn_ti												Wikipedia:Germ_plasm		cellular_component											owl:Class	
GO:0045495	biolink:NamedThing	pole plasm	Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.	got7fsn_ti	germ plasm|polar plasm													cellular_component											owl:Class	
GO:0036235	biolink:NamedThing	acyl deglucuronidation	The removal of glucuronic acid from an acyl-glucuronide.	got7fsn_ti							bf	2012-05-18T04:24:11Z						biological_process											owl:Class	
GO:0036234	biolink:NamedThing	deglucuronidation	The removal of glucuronic acid from a conjugated substrate.	got7fsn_ti							bf	2012-05-18T04:23:04Z						biological_process											owl:Class	
GO:0071036	biolink:NamedThing	nuclear polyadenylation-dependent snoRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.	got7fsn_ti	nuclear poly(A)-dependent snoRNA catabolic process						krc	2009-07-29T01:04:44Z						biological_process											owl:Class	
GO:0016077	biolink:NamedThing	sno(s)RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.	got7fsn_ti	sRNA catabolic process|sno(s)RNA breakdown|snoRNA catabolic process|sno(s)RNA degradation|sno(s)RNA catabolism	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0008513	biolink:NamedThing	secondary active organic cation transmembrane transporter activity	Enables the transfer of organic cations from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.	got7fsn_ti	organic cation porter activity|polyspecific organic cation transmembrane transporter activity										GO:0015354	Reactome:R-HSA-549241		molecular_function											owl:Class	
GO:0015101	biolink:NamedThing	organic cation transmembrane transporter activity	Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.	got7fsn_ti												Reactome:R-HSA-561072|Reactome:R-HSA-549304|Reactome:R-HSA-561054|Reactome:R-HSA-2161500|Reactome:R-HSA-549279|Reactome:R-HSA-549129|Reactome:R-HSA-549322		molecular_function											owl:Class	
GO:0002543	biolink:NamedThing	activation of blood coagulation via clotting cascade	Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.	got7fsn_ti	activation of clotting cascade													biological_process											owl:Class	
GO:0050442	biolink:NamedThing	3-propylmalate synthase activity	Catalysis of the reaction: glyoxylate + H(2)O + pentanoyl-CoA = 3-propylmalate + CoA + H(+).	got7fsn_ti	N-propylmalate synthase activity|pentanoyl-CoA:glyoxylate C-pentanoyltransferase (thioester-hydrolysing, 1-carboxybutyl-forming)|3-(n-propyl)-malate synthase activity|beta-n-propylmalate synthase activity|3-propylmalate glyoxylate-lyase (CoA-pentanoylating) activity											RHEA:14457|MetaCyc:3-PROPYLMALATE-SYNTHASE-RXN|EC:2.3.3.12|KEGG_REACTION:R03040		molecular_function											owl:Class	
GO:0017195	biolink:NamedThing	N-terminal peptidyl-lysine N2-acetylation	The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed.	got7fsn_ti												RESID:AA0048		biological_process											owl:Class	
GO:0018076	biolink:NamedThing	N-terminal peptidyl-lysine acetylation	The acetylation of the N-terminal lysine of proteins.	got7fsn_ti														biological_process											owl:Class	
GO:2001029	biolink:NamedThing	regulation of cellular glucuronidation	Any process that modulates the frequency, rate or extent of cellular glucuronidation.	got7fsn_ti	regulation of cellular glucuronoside biosynthesis|regulation of cellular glucuronide biosynthetic process|regulation of cellular glucuronoside biosynthetic process|regulation of cellular glucuronide biosynthesis						rl	2011-08-22T01:10:52Z						biological_process											owl:Class	
GO:0042809	biolink:NamedThing	vitamin D receptor binding	Binding to a vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes.	got7fsn_ti	VDR binding|calciferol receptor binding													molecular_function											owl:Class	
GO:0044493	biolink:NamedThing	envenomation resulting in negative regulation of voltage-gated sodium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism.	got7fsn_ti							jl	2012-02-01T01:26:59Z						biological_process											owl:Class	
GO:0044492	biolink:NamedThing	envenomation resulting in modulation of voltage-gated sodium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism.	got7fsn_ti							jl	2012-02-01T01:23:04Z						biological_process											owl:Class	
GO:0098847	biolink:NamedThing	sequence-specific single stranded DNA binding	Binding to single-stranded DNA of a specific nucleotide composition.	got7fsn_ti														molecular_function											owl:Class	
GO:0003697	biolink:NamedThing	single-stranded DNA binding	Binding to single-stranded DNA.	got7fsn_ti	ssDNA binding				Note that this term is restricted to those cases where the binding is to a single-stranded DNA molecule, not to one of the stands of double-stranded DNA.						GO:0003698|GO:0003699			molecular_function											owl:Class	
GO:0039680	biolink:NamedThing	actin-dependent intracellular transport of virus towards nucleus	The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments.	got7fsn_ti	actin-dependent intracellular transport of viral material towards nucleus|actin-dependent inwards viral transport						bf	2013-10-10T11:24:56Z				VZ:991		biological_process											owl:Class	
GO:0075520	biolink:NamedThing	actin-dependent intracellular transport of virus	The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions.	got7fsn_ti	actin-dependent intracellular transport of viral material						jl	2011-08-03T01:45:55Z				VZ:991		biological_process											owl:Class	
GO:0036217	biolink:NamedThing	dGTP diphosphatase activity	Catalysis of the reaction: dGTP + H2O = dGMP + diphosphate.	got7fsn_ti	2'-deoxyguanosine 5'-triphosphate diphosphohydrolase						bf	2012-05-08T01:47:59Z				KEGG_REACTION:R01855|RHEA:28362		molecular_function											owl:Class	
GO:0003267	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation	A canonical Wnt signaling pathway that contributes to an increase in the frequency, or rate of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of second heart field cardioblast proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of secondary heart field cardioblast proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation						dph	2009-10-15T02:36:08Z						biological_process											owl:Class	
GO:0140662	biolink:NamedThing	ATP-dependent protein folding chaperone	Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21660					pg	2021-06-19T16:28:34Z						molecular_function											owl:Class	
GO:0044183	biolink:NamedThing	protein folding chaperone	Binding to a protein or a protein-containing complex to assist the protein folding process.	got7fsn_ti	chaperone activity|protein binding involved in protein folding						jl	2009-09-25T11:33:48Z				Reactome:R-HSA-9018785		molecular_function											owl:Class	
GO:0150088	biolink:NamedThing	multiple synapse bouton, contacting multiple dendrites	A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites.	got7fsn_ti	type 2 multiple-synapse bouton|type 2 multisynaptic bouton|type 2 multiple spine synapse bouton|type 2 multi-synaptic bouton|type 2 multisynapse bouton|type 2 multi-synapse bouton|MSB2						bc	2018-08-08T13:31:43Z						cellular_component											owl:Class	
GO:0008299	biolink:NamedThing	isoprenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	got7fsn_ti	polyisoprenoid synthesis|isoprenoid anabolism|polyterpene biosynthetic process|polyisoprenoid biosynthetic process|isoprenoid biosynthesis|isoprenoid synthesis|polyisoprenoid formation|polyisoprenoid anabolism|polyisoprenoid biosynthesis|polyterpene biosynthesis|isoprenoid formation										GO:0009241	MetaCyc:POLYISOPRENSYN-PWY		biological_process											owl:Class	
GO:0110103	biolink:NamedThing	RNA polymerase II termination complex	A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end.	got7fsn_ti	TXT complex				In S. cerevisiae, this complex is formed by RAI1 and RAT1; in H. sapiens it is formed by Twi12, Xrn2 and Tan1.		kmv	2018-03-16T18:55:17Z						cellular_component											owl:Class	
GO:1905354	biolink:NamedThing	exoribonuclease complex	A protein complex which is capable of exoribonuclease activity.	got7fsn_ti					An example of this is DIS3 in human (Q9Y2L1) in PMID:17174896 (inferred from direct assay).		bhm	2016-08-08T10:18:29Z						cellular_component											owl:Class	
GO:0034271	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class III, type I	A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.	got7fsn_ti	phosphatidylinositol 3-kinase complex I|autophagy-specific phosphatidylinositol 3-kinase (PtdIns3K) complex|PtdIns-3-kinase complex I				Note that this term should not be confused with '1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; GO:0005943' or '1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex ; GO:0005944'.									cellular_component											owl:Class	
GO:0035032	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class III	A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).	got7fsn_ti	class III PI3K complex|phosphoinositide 3-kinase complex, class III													cellular_component											owl:Class	
GO:0007518	biolink:NamedThing	myoblast fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0001709	biolink:NamedThing	cell fate determination	A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	got7fsn_ti												Wikipedia:Cell_fate_determination		biological_process											owl:Class	
GO:0034498	biolink:NamedThing	early endosome to Golgi transport	The directed movement of substances from early endosomes to the Golgi.	got7fsn_ti	PGE to Golgi transport|post-Golgi endosome to Golgi transport													biological_process											owl:Class	
GO:0043121	biolink:NamedThing	neurotrophin binding	Binding to a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.	got7fsn_ti	neurotrophin 3 binding|neurotrophin-4/5 binding|neurotrophic factor binding|NT-3 binding|NT-4 binding|neurotrophin 4/5 binding|neurotrophin TRKC receptor activity|neurotrophin TRKB receptor activity|NT-4/5 binding|NT 4/5 binding|neurotrophin-3 binding|NT-5 binding|NT5 binding|NT3 binding|NT4 binding|neurotrophin TRK receptor activity|neurotrophin TRKA receptor activity				Note that mammalian NT-5 was initially named differently from amphibian NT-4 because of sequence differences, but the two genes were later shown to be functionally equivalent [SF:919858].						GO:0048404|GO:0048405			molecular_function											owl:Class	
GO:0019838	biolink:NamedThing	growth factor binding	Binding to a growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.	got7fsn_ti	neurotrophin TRK receptor activity													molecular_function											owl:Class	
GO:0052201	biolink:NamedThing	response to symbiont defenses	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:1990734	biolink:NamedThing	astral microtubule anchoring at mitotic spindle pole body	Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.	got7fsn_ti							vw	2015-04-28T12:15:18Z						biological_process											owl:Class	
GO:0034631	biolink:NamedThing	microtubule anchoring at spindle pole body	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.	got7fsn_ti	attachment of spindle microtubules to spindle pole body|microtubule anchoring at SPB|attachment of spindle microtubules to SPB													biological_process											owl:Class	
GO:0102516	biolink:NamedThing	delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+.	got7fsn_ti												MetaCyc:RXN-14448		molecular_function											owl:Class	
GO:0003300	biolink:NamedThing	cardiac muscle hypertrophy	The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.	got7fsn_ti							dph	2009-10-22T10:33:56Z						biological_process											owl:Class	
GO:0014897	biolink:NamedThing	striated muscle hypertrophy	The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.	got7fsn_ti														biological_process											owl:Class	
GO:0010028	biolink:NamedThing	xanthophyll cycle	A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II.	got7fsn_ti												Wikipedia:Xanthophyll#Xanthophyll_cycle|MetaCyc:PWY-1141		biological_process											owl:Class	
GO:0016122	biolink:NamedThing	xanthophyll metabolic process	The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.	got7fsn_ti	xanthophyll metabolism													biological_process											owl:Class	
GO:0035652	biolink:NamedThing	clathrin-coated vesicle cargo loading	Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle.	got7fsn_ti	cargo loading into clathrin-coated vesicle						bf	2011-01-25T11:00:43Z						biological_process											owl:Class	
GO:0035459	biolink:NamedThing	vesicle cargo loading	The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.	got7fsn_ti	cargo loading into vesicle|cargo selection						bf	2010-04-16T01:14:06Z						biological_process											owl:Class	
GO:0036306	biolink:NamedThing	embryonic heart tube elongation	The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.	got7fsn_ti							bf	2012-08-08T13:54:37Z						biological_process											owl:Class	
GO:0110018	biolink:NamedThing	cap-independent translational initiation of circular RNA	The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.	got7fsn_ti	cap-independent translational initiation of circRNA						kmv	2017-06-08T15:22:35Z						biological_process											owl:Class	
GO:0002190	biolink:NamedThing	cap-independent translational initiation	The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation.	got7fsn_ti							hjd	2011-08-11T02:16:05Z						biological_process											owl:Class	
GO:0033000	biolink:NamedThing	Fc-gamma receptor I complex	A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG.	got7fsn_ti	immunoglobulin G receptor complex|IgG receptor complex|FcgRI complex													cellular_component											owl:Class	
GO:0034856	biolink:NamedThing	2-hydroxyhexa-2,4-dienoate hydratase activity	Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate.	got7fsn_ti												RHEA:32535|EC:4.2.1.132|UM-BBD_reactionID:r1281		molecular_function											owl:Class	
GO:0140292	biolink:NamedThing	ADP-ribosylserine hydrolase activity	Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.	got7fsn_ti							pg	2018-11-22T14:35:39Z						molecular_function											owl:Class	
GO:0048372	biolink:NamedThing	lateral mesodermal cell fate commitment	The process in which a cell becomes committed to become a lateral mesoderm cell.	got7fsn_ti	lateral plate mesodermal cell fate commitment|lateral mesoderm cell fate commitment|lateral plate mesoderm cell fate commitment													biological_process											owl:Class	
GO:0052903	biolink:NamedThing	N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	Catalysis of the reaction: H(2)O + N(1)-acetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + spermidine.	got7fsn_ti	non-specific polyamine oxidase activity|N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity											EC:1.5.3.17|MetaCyc:RXN-9940|RHEA:25800|KEGG_REACTION:R03899|EC:1.5.3.13|MetaCyc:RXN-12090		molecular_function											owl:Class	
GO:0036530	biolink:NamedThing	protein deglycation, methylglyoxal removal	The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein.	got7fsn_ti	protein deglycation of methylglyoxal-glycated protein						bf	2016-08-04T10:42:26Z						biological_process											owl:Class	
GO:0009438	biolink:NamedThing	methylglyoxal metabolic process	The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.	got7fsn_ti	methylglyoxal metabolism|methylglyoxal pathway|methylglyoxal bypass											MetaCyc:METHGLYUT-PWY		biological_process											owl:Class	
GO:0018861	biolink:NamedThing	4-chlorobenzoate-CoA ligase activity	Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway.	got7fsn_ti	4-chlorobenzoate:CoA ligase activity											KEGG_REACTION:R03932|EC:6.2.1.33|RHEA:23220|MetaCyc:6.2.1.33-RXN|UM-BBD_reactionID:r0139		molecular_function											owl:Class	
GO:0062037	biolink:NamedThing	D-loop DNA binding	Binding to a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind.	got7fsn_ti	DNA displacement loop binding						dph	2018-04-30T15:21:21Z						molecular_function											owl:Class	
GO:0000217	biolink:NamedThing	DNA secondary structure binding	Binding to a DNA secondary structure element such as a four-way junction, a bubble, a loop, Y-form DNA, or a double-strand/single-strand junction.	got7fsn_ti														molecular_function											owl:Class	
GO:0015361	biolink:NamedThing	low-affinity sodium:dicarboxylate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low affinity sodium:dicarboxylate symporter activity|low affinity sodium:dicarboxylate cotransporter activity											Reactome:R-HSA-433131		molecular_function											owl:Class	
GO:0017153	biolink:NamedThing	sodium:dicarboxylate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in).	got7fsn_ti	sodium:dicarboxylate cotransporter activity													molecular_function											owl:Class	
GO:0042369	biolink:NamedThing	vitamin D catabolic process	The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	got7fsn_ti	cholecalciferol biosynthesis|calciferol catabolism|vitamin D degradation|ergocalciferol biosynthetic process|calciferol catabolic process|vitamin D catabolism|vitamin D breakdown|ergocalciferol biosynthesis|cholecalciferol biosynthetic process													biological_process											owl:Class	
GO:0042363	biolink:NamedThing	fat-soluble vitamin catabolic process	The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.	got7fsn_ti	fat-soluble vitamin degradation|fat-soluble vitamin breakdown|fat-soluble vitamin catabolism													biological_process											owl:Class	
GO:0001733	biolink:NamedThing	galactosylceramide sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.	got7fsn_ti	3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity|galactocerebroside sulfotransferase activity|galactolipid sulfotransferase activity|glycosphingolipid sulfotransferase activity|cerebroside sulfotransferase activity|GSase|galactosylceramide sulphotransferase activity|glycolipid sulfotransferase activity|3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity											MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN|EC:2.8.2.11|RHEA:43304		molecular_function											owl:Class	
GO:0050694	biolink:NamedThing	galactose 3-O-sulfotransferase activity	Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc.	got7fsn_ti	galactose 3-O-sulphotransferase activity|Gal-3-O-sulfotransferase activity													molecular_function											owl:Class	
GO:0070262	biolink:NamedThing	peptidyl-serine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.	got7fsn_ti														biological_process											owl:Class	
GO:0102176	biolink:NamedThing	cycloeucalenone reductase activity	Catalysis of the reaction: cycloeucalenone + NADPH + H+ <=> cycloeucalenol + NADP.	got7fsn_ti												EC:1.1.1.270|MetaCyc:RXN-11929		molecular_function											owl:Class	
GO:1990175	biolink:NamedThing	EH domain binding	Binding to an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R.	got7fsn_ti							hjd	2013-08-27T20:14:56Z						molecular_function											owl:Class	
GO:0075112	biolink:NamedThing	modulation by symbiont of host transmembrane receptor-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075081".									biological_process											owl:Class	
GO:0075109	biolink:NamedThing	modulation by symbiont of host receptor-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont receptor-mediated signal transduction ; GO:0075078".									biological_process											owl:Class	
GO:0030645	biolink:NamedThing	glucose catabolic process to butyrate	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.	got7fsn_ti	butyrate fermentation|glucose fermentation to butyrate													biological_process											owl:Class	
GO:0006113	biolink:NamedThing	fermentation	The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).	got7fsn_ti												MetaCyc:FERMENTATION-PWY|Wikipedia:Fermentation_(biochemistry)		biological_process											owl:Class	
GO:0072671	biolink:NamedThing	mitochondria-associated ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.	got7fsn_ti	MAD|mitochondria-associated protein catabolic process|mitochondria-associated protein degradation|mitochondrion-associated protein catabolic process						mah	2011-02-18T11:53:28Z						biological_process											owl:Class	
GO:0140633	biolink:NamedThing	CARD8 inflammasome complex assembly	The aggregation, arrangement and bonding together of a set of components to form a CARD8 inflammasome complex.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21092					pg	2021-04-09T11:19:51Z						biological_process											owl:Class	
GO:0140632	biolink:NamedThing	inflammasome complex assembly	The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21092					pg	2021-04-09T11:11:41Z						biological_process											owl:Class	
GO:0043605	biolink:NamedThing	cellular amide catabolic process	The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.	got7fsn_ti														biological_process											owl:Class	
GO:0102486	biolink:NamedThing	dCTP phosphohydrolase activity	Catalysis of the reaction: dCTP + 2 H2O = dCMP + 2 hydrogenphosphate + 2 H+.	got7fsn_ti												EC:3.6.1.5|MetaCyc:RXN-14198		molecular_function											owl:Class	
GO:0031857	biolink:NamedThing	type 1 parathyroid hormone receptor binding	Binding to a type 1 parathyroid hormone receptor.	got7fsn_ti	type 1 parathyroid hormone receptor ligand													molecular_function											owl:Class	
GO:0031856	biolink:NamedThing	parathyroid hormone receptor binding	Binding to a parathyroid hormone receptor.	got7fsn_ti	parathyroid hormone receptor ligand													molecular_function											owl:Class	
GO:0033064	biolink:NamedThing	XRCC2-RAD51D complex	A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast.	got7fsn_ti	DX2 complex													cellular_component											owl:Class	
GO:0033061	biolink:NamedThing	DNA recombinase mediator complex	A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA through facilitating recombinase-RPA exchange.	got7fsn_ti					Many paralogs of Rad51 act as recombinase mediators. These paralogs dimerize (or occasionally form tetramers) amongst themselves to form complexes with ssDNA-binding activity, and which act as mediators of Rad51 presynaptic filament assembly.									cellular_component											owl:Class	
GO:0060530	biolink:NamedThing	smooth muscle cell differentiation involved in prostate glandular acinus development	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.	got7fsn_ti														biological_process											owl:Class	
GO:0006884	biolink:NamedThing	cell volume homeostasis	Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.	got7fsn_ti	regulation of cell volume													biological_process											owl:Class	
GO:0019725	biolink:NamedThing	cellular homeostasis	Any process involved in the maintenance of an internal steady state at the level of the cell.	got7fsn_ti														biological_process											owl:Class	
GO:0050202	biolink:NamedThing	octopamine dehydratase activity	Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH(4)(+).	got7fsn_ti	octopamine hydrolyase activity|octopamine hydro-lyase (deaminating)|octopamine hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming]											EC:4.2.1.87|KEGG_REACTION:R03358|RHEA:18173|MetaCyc:OCTOPAMINE-DEHYDRATASE-RXN		molecular_function											owl:Class	
GO:0035486	biolink:NamedThing	cytosine/cytosine mispair binding	Binding to a double-stranded DNA region containing a C/C mispair.	got7fsn_ti	C/C mispair binding						bf	2010-04-23T10:56:10Z						molecular_function											owl:Class	
GO:0003321	biolink:NamedThing	positive regulation of blood pressure by epinephrine-norepinephrine	Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine.	got7fsn_ti							dph	2009-10-29T01:52:50Z						biological_process											owl:Class	
GO:0001993	biolink:NamedThing	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system.	got7fsn_ti	norepinephrine-epinephrine blood pressure control|norepinephrine-epinephrine blood pressure regulation|noradrenaline-adrenaline regulation of blood pressure													biological_process											owl:Class	
GO:0061127	biolink:NamedThing	negative regulation of positive chemotaxis to cAMP by DIF-1	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.	got7fsn_ti							dph	2010-05-17T08:45:03Z						biological_process											owl:Class	
GO:0061120	biolink:NamedThing	regulation of positive chemotaxis to cAMP by DIF-1	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.	got7fsn_ti							dph	2010-05-17T08:10:20Z						biological_process											owl:Class	
GO:1990845	biolink:NamedThing	adaptive thermogenesis	The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.	got7fsn_ti							sl	2015-08-31T18:19:49Z						biological_process											owl:Class	
GO:0048559	biolink:NamedThing	establishment of floral organ orientation	The process that determines the orientation of the floral organs with reference to the central axis of the flower.	got7fsn_ti														biological_process											owl:Class	
GO:0102157	biolink:NamedThing	(R)-sulfopropanediol 2-dehydrogenase activity	Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD <=> 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+.	got7fsn_ti												MetaCyc:RXN-11729		molecular_function											owl:Class	
GO:0031615	biolink:NamedThing	cytosolic proteasome regulatory particle, lid subcomplex	The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.	got7fsn_ti														cellular_component											owl:Class	
GO:0008541	biolink:NamedThing	proteasome regulatory particle, lid subcomplex	The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.	got7fsn_ti														cellular_component											owl:Class	
GO:0046310	biolink:NamedThing	1,3-dichloro-2-propanol catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic.	got7fsn_ti	1,3-dichloro-2-propanol catabolism|1,3-dichloro-2-propanol breakdown|1,3-dichloro-2-propanol degradation													biological_process											owl:Class	
GO:0044109	biolink:NamedThing	cellular alcohol catabolic process	The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, occurring at the level of the individual cell.	got7fsn_ti							jl	2009-07-15T01:44:27Z						biological_process											owl:Class	
GO:0034238	biolink:NamedThing	macrophage fusion	The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0000768	biolink:NamedThing	syncytium formation by plasma membrane fusion	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	got7fsn_ti	cell fusion													biological_process											owl:Class	
GO:0070736	biolink:NamedThing	protein-glycine ligase activity, initiating	Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein.	got7fsn_ti	protein glycylase activity, initiating						mah	2009-06-19T01:56:32Z						molecular_function											owl:Class	
GO:0070735	biolink:NamedThing	protein-glycine ligase activity	Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein.	got7fsn_ti	protein glycylase activity						mah	2009-06-19T01:51:21Z				Reactome:R-HSA-8867370		molecular_function											owl:Class	
GO:0140497	biolink:NamedThing	mannan polymerase II complex	A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p, Anp1p, Mnn10p, Mnn11p, and Hoc1p.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19817					pg	2020-07-22T14:33:57Z						cellular_component											owl:Class	
GO:0000136	biolink:NamedThing	mannan polymerase complex	A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.	got7fsn_ti	alpha-1,6-mannosyltransferase complex	https://github.com/geneontology/go-ontology/issues/19817												cellular_component											owl:Class	
GO:0020007	biolink:NamedThing	apical complex	A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation.	got7fsn_ti														cellular_component											owl:Class	
GO:0060492	biolink:NamedThing	lung induction	The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung.	got7fsn_ti														biological_process											owl:Class	
GO:0001759	biolink:NamedThing	organ induction	The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.	got7fsn_ti	induction of an organ													biological_process											owl:Class	
GO:0019600	biolink:NamedThing	toluene oxidation	The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene.	got7fsn_ti														biological_process											owl:Class	
GO:0018970	biolink:NamedThing	toluene metabolic process	The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications.	got7fsn_ti	methylbenzene metabolic process|toluene metabolism|methylbenzene metabolism													biological_process											owl:Class	
GO:0008635	biolink:NamedThing	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.	got7fsn_ti	caspase activation via cytochrome c|activation of caspase activity by cytochrome c													biological_process											owl:Class	
GO:0006919	biolink:NamedThing	activation of cysteine-type endopeptidase activity involved in apoptotic process	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.	got7fsn_ti	activation of caspase activity|caspase activation|activation of metacaspase activity				This term should be used when the annotation refers to a process that occurs in a context of apoptotic cell death. To annotate gene products involved in activation of cysteine-type endopeptidases in other cellular process (e.g., cell cycle arrest) that do not necessarily develop into an apoptotic process, please use the more general parent term GO:0097202. Examples of 'activation of cysteine-type endopeptidase activity involved in apoptotic process' are cytochrome c and Apaf1. When cytochrome c is released from mitochondria and forms a complex with Apaf1, they form a scaffolding platform in which the pro-caspase 9 is bound (the 'apoptosome'). The caspase is then cleaved and activated. Cytochrome c and Apaf1 are therefore involved in the conversion of the zymogen procaspase 9 to the active form of the caspase.									biological_process											owl:Class	
GO:0004507	biolink:NamedThing	steroid 11-beta-monooxygenase activity	Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.	got7fsn_ti	steroid 11beta-monooxygenase activity|steroid 11beta-hydroxylase activity|steroid 11beta/18-hydroxylase activity|cytochrome P450 CYP11B2|cytochrome p450 XIB1 activity|cytochrome P450 CYP11B1|steroid 11-beta-hydroxylase activity|steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)|oxygenase, steroid 11beta -mono-|steroid 11-beta/18-hydroxylase activity											Reactome:R-HSA-5600598|EC:1.14.15.4|Reactome:R-HSA-5580292|Reactome:R-HSA-193997|MetaCyc:STEROID-11-BETA-MONOOXYGENASE-RXN|Reactome:R-HSA-194017|RHEA:15629		molecular_function											owl:Class	
GO:0042679	biolink:NamedThing	compound eye cone cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti											GO:0042678			biological_process											owl:Class	
GO:0001708	biolink:NamedThing	cell fate specification	The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	got7fsn_ti														biological_process											owl:Class	
GO:0015643	biolink:NamedThing	toxic substance binding	Binding to a toxic substance, a poisonous substance that causes damage to biological systems.	got7fsn_ti	antitoxin activity|lipoprotein antitoxin													molecular_function											owl:Class	
GO:0006937	biolink:NamedThing	regulation of muscle contraction	Any process that modulates the frequency, rate or extent of muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0090257	biolink:NamedThing	regulation of muscle system process	Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.	got7fsn_ti							tb	2010-02-03T11:48:13Z						biological_process											owl:Class	
GO:0015030	biolink:NamedThing	Cajal body	A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.	got7fsn_ti	Gems|coiled body|Gemini of coiled bodies											Wikipedia:Cajal_body|NIF_Subcellular:nlx_subcell_090901		cellular_component											owl:Class	
GO:0102255	biolink:NamedThing	neo-lambda-carrahexaose hydrolase activity	Catalysis of the reaction: neo-lambda-carrahexaose + H2O <=> neo-lambda-carratetraose + neo-lambda-carrabiose.	got7fsn_ti												MetaCyc:RXN-12428|EC:3.2.1.162		molecular_function											owl:Class	
GO:0030500	biolink:NamedThing	regulation of bone mineralization	Any process that modulates the frequency, rate or extent of bone mineralization.	got7fsn_ti														biological_process											owl:Class	
GO:0030278	biolink:NamedThing	regulation of ossification	Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.	got7fsn_ti	regulation of bone biosynthesis|regulation of bone formation													biological_process											owl:Class	
GO:0046530	biolink:NamedThing	photoreceptor cell differentiation	The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster.	got7fsn_ti											GO:0007467			biological_process											owl:Class	
GO:0030182	biolink:NamedThing	neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron.	got7fsn_ti														biological_process											owl:Class	
GO:0106033	biolink:NamedThing	spine synapse	A type of synapse occurring between an axon and a dendritic spine.	got7fsn_ti	dendritic spine synapse						hjd	2017-07-05T19:20:48Z						cellular_component											owl:Class	
GO:0032279	biolink:NamedThing	asymmetric synapse	A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density.  Most or all synapses of this type are excitatory.	got7fsn_ti	Gray's type I synapse													cellular_component											owl:Class	
GO:0010129	biolink:NamedThing	anaerobic cyclohexane-1-carboxylate catabolic process	The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen.	got7fsn_ti	anaerobic cyclohexane-1-carboxylate catabolism|anaerobic cyclohexane-1-carboxylate breakdown|anaerobic cyclohexane-1-carboxylate degradation											MetaCyc:PWY-301		biological_process											owl:Class	
GO:0019439	biolink:NamedThing	aromatic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.	got7fsn_ti	aromatic compound breakdown|aromatic hydrocarbon catabolism|aromatic hydrocarbon catabolic process|aromatic compound catabolism|aromatic compound degradation													biological_process											owl:Class	
GO:0036029	biolink:NamedThing	protein C inhibitor-KLK3 complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen.	got7fsn_ti	SERPINA5-KLK3 complex|protein C inhibitor-prostate-specific antigen complex|PCI-KLK3 complex|protein C inhibitor-kallikrein-3 complex|serpin A5-KLK3 complex|plasma serine protease inhibitor-KLK3 complex						bf	2011-10-19T02:01:33Z						cellular_component											owl:Class	
GO:0018022	biolink:NamedThing	peptidyl-lysine methylation	The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.	got7fsn_ti														biological_process											owl:Class	
GO:0006479	biolink:NamedThing	protein methylation	The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.	got7fsn_ti	protein amino acid methylation													biological_process											owl:Class	
GO:0060608	biolink:NamedThing	cell-cell adhesion involved in neural tube closure	The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.	got7fsn_ti							dph	2009-05-15T09:56:14Z						biological_process											owl:Class	
GO:0060607	biolink:NamedThing	cell-cell adhesion involved in sealing an epithelial fold	The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube.	got7fsn_ti							dph	2009-05-15T09:48:49Z						biological_process											owl:Class	
GO:0021747	biolink:NamedThing	cochlear nucleus development	The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0048857	biolink:NamedThing	neural nucleus development	The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.	got7fsn_ti														biological_process											owl:Class	
GO:0047904	biolink:NamedThing	fructose 5-dehydrogenase activity	Catalysis of the reaction: D-fructose + A = 5-dehydro-D-fructose + AH(2).	got7fsn_ti	fructose 5-dehydrogenase (acceptor)|D-fructose:acceptor 5-oxidoreductase activity|D-fructose dehydrogenase activity|D-fructose:(acceptor) 5-oxidoreductase activity											MetaCyc:FRUCTOSE-5-DEHYDROGENASE-RXN|EC:1.1.99.11|RHEA:22304|KEGG_REACTION:R00873		molecular_function											owl:Class	
GO:0048066	biolink:NamedThing	developmental pigmentation	The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.	got7fsn_ti	pigmentation during development													biological_process											owl:Class	
GO:0031669	biolink:NamedThing	cellular response to nutrient levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.	got7fsn_ti														biological_process											owl:Class	
GO:0002244	biolink:NamedThing	hematopoietic progenitor cell differentiation	The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.	got7fsn_ti	haematopoietic progenitor cell differentiation|haemopoietic progenitor cell differentiation|hemopoietic progenitor cell differentiation													biological_process											owl:Class	
GO:0047871	biolink:NamedThing	disulfoglucosamine-6-sulfatase activity	Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H(2)O = N-sulfo-D-glucosamine + H(+) + sulfate.	got7fsn_ti	6,N-disulfoglucosamine 6-O-sulfohydrolase activity|N,6-O-disulfo-D-glucosamine 6-sulfohydrolase activity|N-sulfoglucosamine-6-sulfatase activity|disulphoglucosamine-6-sulphatase activity											KEGG_REACTION:R03216|RHEA:15517|EC:3.1.6.11|MetaCyc:DISULFOGLUCOSAMINE-6-SULFATASE-RXN		molecular_function											owl:Class	
GO:0102363	biolink:NamedThing	isoscopoletin-O-methyltransferase activity	Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine  <=> scoparone + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-13475		molecular_function											owl:Class	
GO:0050743	biolink:NamedThing	protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine	The formation of a protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine.	got7fsn_ti												RESID:AA0352		biological_process											owl:Class	
GO:0034705	biolink:NamedThing	potassium channel complex	An ion channel complex through which potassium ions pass.	got7fsn_ti														cellular_component											owl:Class	
GO:0062145	biolink:NamedThing	L-propargylglycine--L-glutamate ligase activity	Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate.	got7fsn_ti							dph	2019-09-02T16:56:59Z				RHEA:59896		molecular_function											owl:Class	
GO:0097722	biolink:NamedThing	sperm motility	Any process involved in the controlled movement of a sperm cell.	got7fsn_ti	sperm movement						pr	2016-09-01T12:00:45Z						biological_process											owl:Class	
GO:0019686	biolink:NamedThing	purine nucleoside interconversion	The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.	got7fsn_ti														biological_process											owl:Class	
GO:0015949	biolink:NamedThing	nucleobase-containing small molecule interconversion	The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.	got7fsn_ti												MetaCyc:P1-PWY		biological_process											owl:Class	
GO:0031097	biolink:NamedThing	medial cortex	A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.	got7fsn_ti	medial ring													cellular_component											owl:Class	
GO:1903488	biolink:NamedThing	negative regulation of lactation	Any process that stops, prevents or reduces the frequency, rate or extent of lactation.	got7fsn_ti	down regulation of lactation|down-regulation of lactation|downregulation of lactation|inhibition of lactation						mr	2014-09-24T14:44:22Z						biological_process											owl:Class	
GO:0072072	biolink:NamedThing	kidney stroma development	The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.	got7fsn_ti							mah	2010-01-25T04:35:36Z						biological_process											owl:Class	
GO:0006995	biolink:NamedThing	cellular response to nitrogen starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.	got7fsn_ti														biological_process											owl:Class	
GO:0070657	biolink:NamedThing	neuromast regeneration	The regrowth of a neuromast following its loss or destruction.	got7fsn_ti							mah	2009-05-28T04:11:44Z						biological_process											owl:Class	
GO:0070655	biolink:NamedThing	mechanosensory epithelium regeneration	The regrowth of lost or destroyed mechanosensory epithelia.	got7fsn_ti							mah	2009-05-28T04:05:18Z						biological_process											owl:Class	
GO:0034868	biolink:NamedThing	2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1273		molecular_function											owl:Class	
GO:0032981	biolink:NamedThing	mitochondrial respiratory chain complex I assembly	The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.	got7fsn_ti	mitochondrial complex I assembly|mitochondrial NADH dehydrogenase complex (ubiquinone) assembly													biological_process											owl:Class	
GO:0033108	biolink:NamedThing	mitochondrial respiratory chain complex assembly	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.	got7fsn_ti														biological_process											owl:Class	
GO:0050665	biolink:NamedThing	hydrogen peroxide biosynthetic process	The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	got7fsn_ti	hydrogen peroxide formation|H2O2 biosynthetic process|hydrogen peroxide synthesis|hydrogen peroxide anabolism|hydrogen peroxide generation|hydrogen peroxide biosynthesis													biological_process											owl:Class	
GO:0034567	biolink:NamedThing	chromate reductase activity	Catalysis of the reaction: chromate = chromium (III).	got7fsn_ti												UM-BBD_reactionID:r0884|EC:1.97.1.-		molecular_function											owl:Class	
GO:0090592	biolink:NamedThing	DNA synthesis involved in DNA replication	Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA.	got7fsn_ti							tb	2014-06-06T13:54:36Z						biological_process											owl:Class	
GO:0071897	biolink:NamedThing	DNA biosynthetic process	The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.	got7fsn_ti	DNA biosynthesis|DNA anabolism|DNA formation|DNA synthesis						mah	2010-09-15T02:14:33Z						biological_process											owl:Class	
GO:0031868	biolink:NamedThing	prostaglandin F2-alpha receptor binding	Binding to a prostaglandin F2-alpha receptor.	got7fsn_ti	prostanoid FP receptor binding|prostaglandin F2-alpha receptor ligand													molecular_function											owl:Class	
GO:0031862	biolink:NamedThing	prostanoid receptor binding	Binding to a prostanoid receptor.	got7fsn_ti	prostanoid receptor ligand													molecular_function											owl:Class	
GO:0016517	biolink:NamedThing	interleukin-12 receptor activity	Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-12R|IL-12 receptor activity													molecular_function											owl:Class	
GO:0003990	biolink:NamedThing	acetylcholinesterase activity	Catalysis of the reaction: acetylcholine + H2O = choline + acetate.	got7fsn_ti	true cholinesterase activity|choline esterase I activity|acetylthiocholinesterase activity|acetyl.beta-methylcholinesterase activity|AcCholE|acetylcholine hydrolase activity|acetylcholine acetylhydrolase activity											EC:3.1.1.7|MetaCyc:ACETYLCHOLINESTERASE-RXN|Reactome:R-HSA-372519|RHEA:17561		molecular_function											owl:Class	
GO:0004104	biolink:NamedThing	cholinesterase activity	Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.	got7fsn_ti	butyrylcholinesterase activity|butyrylcholine esterase activity|BtChoEase activity|anticholineesterase activity|pseudocholinesterase activity|acylcholine acylhydrolase activity|choline esterase II (unspecific) activity|non-specific cholinesterase activity|choline esterase activity|propionylcholinesterase activity|benzoylcholinesterase activity											RHEA:21964|MetaCyc:CHOLINESTERASE-RXN|EC:3.1.1.8		molecular_function											owl:Class	
GO:0051366	biolink:NamedThing	protein decanoylation	The modification of a protein amino acid by formation of an ester or amide with decanoic acid.	got7fsn_ti	protein amino acid decanoylation													biological_process											owl:Class	
GO:0043543	biolink:NamedThing	protein acylation	The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.	got7fsn_ti	protein amino acid acylation													biological_process											owl:Class	
GO:0031546	biolink:NamedThing	brain-derived neurotrophic factor receptor binding	Binding to a brain-derived neurotrophic factor receptor.	got7fsn_ti	BDNF receptor binding|brain-derived neurotrophic factor ligand													molecular_function											owl:Class	
GO:0005165	biolink:NamedThing	neurotrophin receptor binding	Binding to a neurotrophin receptor.	got7fsn_ti	neurotrophin receptor ligand|neurotrophin													molecular_function											owl:Class	
GO:0046009	biolink:NamedThing	positive regulation of female receptivity, post-mating	Any process that increases the receptiveness of a female to male advances subsequent to mating.	got7fsn_ti	activation of female receptivity, post-mating|stimulation of female receptivity, post-mating|up-regulation of female receptivity, post-mating|upregulation of female receptivity, post-mating|up regulation of female receptivity, post-mating													biological_process											owl:Class	
GO:0046008	biolink:NamedThing	regulation of female receptivity, post-mating	Any process that modulates the receptiveness of a female to male advances subsequent to mating.	got7fsn_ti														biological_process											owl:Class	
GO:0050892	biolink:NamedThing	intestinal absorption	Any process in which nutrients are taken up from the contents of the intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0022600	biolink:NamedThing	digestive system process	A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0070146	biolink:NamedThing	mitochondrial aspartyl-tRNA aminoacylation	The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0045263	biolink:NamedThing	proton-transporting ATP synthase complex, coupling factor F(o)	All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins.	got7fsn_ti	hydrogen-transporting ATP synthase, coupling factor CF(0)|hydrogen-transporting ATP synthase complex, coupling factor F(o)|proton-transporting ATP synthase complex, coupling factor F(0)|hydrogen-transporting ATP synthase, F0 sector													cellular_component											owl:Class	
GO:0033177	biolink:NamedThing	proton-transporting two-sector ATPase complex, proton-transporting domain	A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0050146	biolink:NamedThing	nucleoside phosphotransferase activity	Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate.	got7fsn_ti	nucleotide:2'-nucleoside 5'-phosphotransferase activity|nucleotide:3'-deoxynucleoside 5'-phosphotransferase activity|nucleotide:nucleoside 5'-phosphotransferase activity|nonspecific nucleoside phosphotransferase activity											MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN|RHEA:19961|Reactome:R-HSA-2162066|EC:2.7.1.77		molecular_function											owl:Class	
GO:0019205	biolink:NamedThing	nucleobase-containing compound kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate.	got7fsn_ti	nucleobase, nucleoside, nucleotide kinase activity													molecular_function											owl:Class	
GO:0042258	biolink:NamedThing	molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide	The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide.	got7fsn_ti												RESID:AA0319		biological_process											owl:Class	
GO:0120140	biolink:NamedThing	negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.	got7fsn_ti							krc	2018-03-22T16:32:59Z						biological_process											owl:Class	
GO:0010921	biolink:NamedThing	regulation of phosphatase activity	Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0000184	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.	got7fsn_ti	nuclear mRNA catabolic process, nonsense-mediated decay|mRNA breakdown, nonsense-mediated decay|mRNA catabolism, nonsense-mediated|mRNA catabolic process, nonsense-mediated|mRNA degradation, nonsense-mediated decay|nonsense-mediated mRNA decay											Wikipedia:Nonsense-mediated_mRNA_decay|Wikipedia:Nonsense-mediated_decay		biological_process											owl:Class	
GO:0000956	biolink:NamedThing	nuclear-transcribed mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.	got7fsn_ti	nuclear mRNA breakdown|nuclear mRNA catabolism|nuclear mRNA degradation													biological_process											owl:Class	
GO:0031872	biolink:NamedThing	type 1 proteinase activated receptor binding	Binding to a type 1 proteinase activated receptor.	got7fsn_ti	type 1 proteinase activated receptor ligand|thrombin receptor binding													molecular_function											owl:Class	
GO:0031871	biolink:NamedThing	proteinase activated receptor binding	Binding to a proteinase activated receptor.	got7fsn_ti	proteinase activated receptor ligand													molecular_function											owl:Class	
GO:0021775	biolink:NamedThing	smoothened signaling pathway involved in ventral spinal cord interneuron specification	The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.	got7fsn_ti	hedgehog signaling pathway involved in ventral spinal cord interneuron specification|hh signaling pathway involved in ventral spinal cord interneuron specification|smoothened signalling pathway involved in ventral spinal cord interneuron specification													biological_process											owl:Class	
GO:0021910	biolink:NamedThing	smoothened signaling pathway involved in ventral spinal cord patterning	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.	got7fsn_ti	hh signaling pathway involved in ventral spinal cord patterning|hedgehog signaling pathway involved in ventral spinal cord patterning|smoothened signalling pathway in ventral spinal cord patterning													biological_process											owl:Class	
GO:0009299	biolink:NamedThing	mRNA transcription	The cellular synthesis of messenger RNA (mRNA) from a DNA template.	got7fsn_ti	mRNA synthesis|cellular mRNA transcription|mRNA biosynthesis|mRNA biosynthetic process										GO:0061023			biological_process											owl:Class	
GO:0006351	biolink:NamedThing	transcription, DNA-templated	The cellular synthesis of RNA on a template of DNA.	got7fsn_ti	transcription|cellular transcription, DNA-dependent|DNA-dependent transcription|transcription, DNA-dependent|transcription regulator activity|cellular transcription										GO:0061018|GO:0006350|GO:0061022	Wikipedia:Transcription_(genetics)		biological_process											owl:Class	
GO:0036513	biolink:NamedThing	Derlin-1 retrotranslocation complex	A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.	got7fsn_ti	Derlin-1 protein dislocation complex|Derlin-1 complex|Derlin-1 retrotranslocon|Derlin-1 retro-translocation complex|ERAD protein dislocation complex				The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.		bf	2015-07-01T10:17:30Z						cellular_component											owl:Class	
GO:0009594	biolink:NamedThing	detection of nutrient	The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of nutrients|detection of nutrients|nutrient sensing													biological_process											owl:Class	
GO:0097422	biolink:NamedThing	tubular endosome	A network of fine tubules in the vicinity of the Golgi complex and around the centriole.	got7fsn_ti	coated tip						pr	2012-11-07T13:36:26Z				NIF_Subcellular:sao1570660411|NIF_Subcellular:sao694815499		cellular_component											owl:Class	
GO:0002207	biolink:NamedThing	gene conversion of immunoglobulin genes involved in immune response	The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response.	got7fsn_ti	gene conversion of antibody genes during immune response|gene conversion of immunoglobulin genes during immune response													biological_process											owl:Class	
GO:0002208	biolink:NamedThing	somatic diversification of immunoglobulins involved in immune response	The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.	got7fsn_ti	somatic diversification of immunoglobulins during immune response|somatic diversification of antibodies during immune response													biological_process											owl:Class	
GO:0008419	biolink:NamedThing	RNA lariat debranching enzyme activity	Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.	got7fsn_ti														molecular_function											owl:Class	
GO:0016891	biolink:NamedThing	endoribonuclease activity, producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.	got7fsn_ti												EC:3.1.26.-		molecular_function											owl:Class	
GO:0120083	biolink:NamedThing	rough endoplasmic reticulum cisterna	A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.	got7fsn_ti							krc	2017-07-05T23:38:49Z						cellular_component											owl:Class	
GO:0008195	biolink:NamedThing	phosphatidate phosphatase activity	Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.	got7fsn_ti	3-sn-phosphatidate phosphohydrolase activity|phosphatic acid phosphohydrolase activity|phosphatic acid phosphatase activity|acid phosphatidyl phosphatase activity|phosphatidic acid phosphatase activity|phosphatidate phosphohydrolase activity										GO:0004606	EC:3.1.3.4|RHEA:27429|Reactome:R-HSA-390329|Reactome:R-HSA-1483203|Reactome:R-HSA-163750|Reactome:R-HSA-75899|Reactome:R-HSA-6797630|Reactome:R-HSA-163689|MetaCyc:PHOSPHATIDATE-PHOSPHATASE-RXN|Reactome:R-HSA-2029468|Reactome:R-HSA-5221130|Reactome:R-HSA-164056|Reactome:R-HSA-163688		molecular_function											owl:Class	
GO:0042131	biolink:NamedThing	thiamine phosphate phosphatase activity	Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate.	got7fsn_ti	thiamin monophosphate phosphatase|thiamin phosphate phosphatase activity|ThMPase													molecular_function											owl:Class	
GO:0003993	biolink:NamedThing	acid phosphatase activity	Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.	got7fsn_ti	acid phosphomonoesterase activity|glycerophosphatase activity|orthophosphoric-monoester phosphohydrolase (acid optimum)|acid phosphomonoester hydrolase activity|uteroferrin|acid phosphohydrolase activity|phosphomonoesterase activity|phosphate-monoester phosphohydrolase (acid optimum)|acid monophosphatase activity|acid nucleoside diphosphate phosphatase activity											Reactome:R-HSA-196950|EC:3.1.3.2|MetaCyc:ACID-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0071781	biolink:NamedThing	endoplasmic reticulum cisternal network	A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae.  These are typically found close to the nucleus and are generally more prominent in secretory cells.	got7fsn_ti	ER cisternal network						mah	2010-09-01T01:29:54Z						cellular_component											owl:Class	
GO:0031984	biolink:NamedThing	organelle subcompartment	A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.	got7fsn_ti	suborganelle compartment				Note that this term refers to membrane-bounded compartments that are not considered organelles in their own right, but form parts of larger organelles.									cellular_component											owl:Class	
GO:0010317	biolink:NamedThing	pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex	Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.	got7fsn_ti	PFK complex, alpha-subunit													cellular_component											owl:Class	
GO:0031930	biolink:NamedThing	mitochondria-nucleus signaling pathway	A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.	got7fsn_ti	retrograde response|mitochondrial signaling pathway|mitochondria-nucleus signal transduction|mitochondrial signalling pathway													biological_process											owl:Class	
GO:0045719	biolink:NamedThing	negative regulation of glycogen biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	got7fsn_ti	negative regulation of glycogen biosynthesis|down regulation of glycogen biosynthetic process|inhibition of glycogen biosynthetic process|negative regulation of glycogen synthesis|negative regulation of glycogen anabolism|downregulation of glycogen biosynthetic process|negative regulation of glycogen formation|down-regulation of glycogen biosynthetic process													biological_process											owl:Class	
GO:0018272	biolink:NamedThing	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine.	got7fsn_ti												RESID:AA0119		biological_process											owl:Class	
GO:0018352	biolink:NamedThing	protein-pyridoxal-5-phosphate linkage	The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0003291	biolink:NamedThing	atrial septum intermedium morphogenesis	The process in which anatomical structure of an atrial septum intermedium is generated and organized.	got7fsn_ti							dph	2009-10-20T10:35:04Z						biological_process											owl:Class	
GO:0060413	biolink:NamedThing	atrial septum morphogenesis	The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.	got7fsn_ti	interatrial septum morphogenesis										GO:0003287			biological_process											owl:Class	
GO:0003838	biolink:NamedThing	sterol 24-C-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol.	got7fsn_ti	S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase activity|S-adenosyl-L-methionine:Delta24(23)-sterol methyltransferase activity|delta24-sterol methyltransferase activity|S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase activity|delta24-methyltransferase activity|sterol 24C methyltransferase activity|delta(24)-methyltransferase activity|phytosterol methyltransferase activity|delta(24)-sterol methyltransferase activity|delta(24)-sterol C-methyltransferase activity|SMT1 activity|S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase activity|S-adenosyl-4-methionine:sterol delta24-methyltransferase activity|zymosterol-24-methyltransferase activity|24-sterol C-methyltransferase activity	https://github.com/geneontology/go-ontology/issues/20399									GO:0102101	MetaCyc:RXN-11201|EC:2.1.1.41|RHEA:21128|MetaCyc:RXN3O-178		molecular_function											owl:Class	
GO:0140602	biolink:NamedThing	nucleolar ring	Ring-like structures located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress.	got7fsn_ti	NuRs	https://github.com/geneontology/go-ontology/issues/20579					pg	2021-02-12T15:38:17Z						cellular_component											owl:Class	
GO:0042405	biolink:NamedThing	nuclear inclusion body	An intranuclear focus at which aggregated proteins have been sequestered.	got7fsn_ti														cellular_component											owl:Class	
GO:0031957	biolink:NamedThing	very long-chain fatty acid-CoA ligase activity	Catalysis of the reaction: ATP + a very-long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	got7fsn_ti	very-long-chain fatty acid-CoA ligase activity|very-long-chain fatty acid activation|very-long-chain-fatty-acid-CoA ligase activity											Reactome:R-HSA-8875077|Reactome:R-HSA-5696007|Reactome:R-HSA-5695957		molecular_function											owl:Class	
GO:1990914	biolink:NamedThing	integral component of periplasmic side of plasma membrane	The component of the plasma membrane consisting of the gene products that penetrate only the periplasmic side of the membrane.	got7fsn_ti					An example of this is hyaA in E. coli (P69739) in PMID:23260654 (inferred from direct assay).		bhm	2015-12-09T14:38:57Z						cellular_component											owl:Class	
GO:0097144	biolink:NamedThing	BAX complex	An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:45:15Z						cellular_component											owl:Class	
GO:0009845	biolink:NamedThing	seed germination	The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.	got7fsn_ti												Wikipedia:Germination#Seed_germination		biological_process											owl:Class	
GO:0080089	biolink:NamedThing	sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity	Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative.	got7fsn_ti							dhl	2009-04-22T03:27:55Z						molecular_function											owl:Class	
GO:0050714	biolink:NamedThing	positive regulation of protein secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.	got7fsn_ti	upregulation of protein secretion|up regulation of protein secretion|stimulation of protein secretion|activation of protein secretion|up-regulation of protein secretion													biological_process											owl:Class	
GO:0018441	biolink:NamedThing	iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide	The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.	got7fsn_ti	iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulphide											RESID:AA0300		biological_process											owl:Class	
GO:0045326	biolink:NamedThing	protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.	got7fsn_ti	DNA-protein covalent cross-linking via the 3'-end to peptidyl-tyrosine											RESID:AA0323		biological_process											owl:Class	
GO:0010425	biolink:NamedThing	DNA methylation on cytosine within a CNG sequence	The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide.	got7fsn_ti	cytosine methylation within a CNG sequence													biological_process											owl:Class	
GO:0032776	biolink:NamedThing	DNA methylation on cytosine	The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule.	got7fsn_ti	cytosine methylation													biological_process											owl:Class	
GO:0035889	biolink:NamedThing	otolith tethering	The attachment of a developing otolith to the kinocilia of tether cells in the inner ear.	got7fsn_ti							bf	2011-06-14T02:28:14Z						biological_process											owl:Class	
GO:0072554	biolink:NamedThing	blood vessel lumenization	The process in which a developing blood vessel forms an endothelial lumen through which blood will flow.	got7fsn_ti							mah	2011-01-25T05:19:30Z						biological_process											owl:Class	
GO:0038184	biolink:NamedThing	cell surface bile acid receptor signaling pathway	A series of molecular signals initiated by binding of a bile acid to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	membrane bile acid receptor signaling pathway						bf	2013-05-16T11:00:42Z						biological_process											owl:Class	
GO:0055040	biolink:NamedThing	periplasmic flagellum	Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella.	got7fsn_ti														cellular_component											owl:Class	
GO:0009288	biolink:NamedThing	bacterial-type flagellum	A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.	got7fsn_ti	flagellin-based flagellum													cellular_component											owl:Class	
GO:0047657	biolink:NamedThing	alpha-1,3-glucan synthase activity	Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.	got7fsn_ti	a-1,3-glucan synthase activity|1,3-alpha-D-glucan synthase activity|uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase activity|UDP-glucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity|1,3-alpha-glucan synthase activity|UDPglucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity											EC:2.4.1.183|RHEA:19749|MetaCyc:ALPHA-13-GLUCAN-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0045549	biolink:NamedThing	9-cis-epoxycarotenoid dioxygenase activity	Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.	got7fsn_ti	VP14|neoxanthin cleavage enzyme|9-cis-epoxycarotenoid 11,12-dioxygenase activity|NCED|nine-cis-epoxycarotenoid dioxygenase activity|PvNCED1|AtNCED3											EC:1.13.11.51		molecular_function											owl:Class	
GO:0010436	biolink:NamedThing	carotenoid dioxygenase activity	Catalysis of the oxidative cleavage of carotenoids.	got7fsn_ti	carotenoid-cleaving dioxygenase													molecular_function											owl:Class	
GO:0036199	biolink:NamedThing	cholest-4-en-3-one 26-monooxygenase activity	Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.	got7fsn_ti							bf	2012-04-20T02:03:05Z				RHEA:51564|KEGG_REACTION:R09859|EC:1.14.15.29		molecular_function											owl:Class	
GO:0042402	biolink:NamedThing	cellular biogenic amine catabolic process	The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.	got7fsn_ti	biogenic amine degradation|biogenic amine catabolism|biogenic amine breakdown													biological_process											owl:Class	
GO:0006576	biolink:NamedThing	cellular biogenic amine metabolic process	The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.	got7fsn_ti	biogenic amine metabolism													biological_process											owl:Class	
GO:0050310	biolink:NamedThing	sulfite dehydrogenase activity	Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c.	got7fsn_ti	sulfite:ferricytochrome-c oxidoreductase activity|sulfite cytochrome c reductase activity|sulfite-cytochrome c oxidoreductase activity|sulphite dehydrogenase activity											RHEA:14281|EC:1.8.2.1|MetaCyc:SULFITE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0016669	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome.	got7fsn_ti	oxidoreductase activity, acting on sulphur group of donors, cytochrome as acceptor											EC:1.8.2.-		molecular_function											owl:Class	
GO:0018207	biolink:NamedThing	peptidyl-phenylalanine modification	The modification of peptidyl-phenylalanine.	got7fsn_ti														biological_process											owl:Class	
GO:0008441	biolink:NamedThing	3'(2'),5'-bisphosphate nucleotidase activity	Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.	got7fsn_ti	3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity|phosphoadenylate 3'-nucleotidase activity|adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity|3'(2'),5' bisphosphate nucleotidase activity|DPNPase activity|3'-phosphoadenylylsulfate 3'-phosphatase activity											RHEA:10040|Reactome:R-HSA-176606|EC:3.1.3.7|Reactome:R-HSA-8953499|MetaCyc:325-BISPHOSPHATE-NUCLEOTIDASE-RXN		molecular_function											owl:Class	
GO:0008252	biolink:NamedThing	nucleotidase activity	Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate.	got7fsn_ti	NSP II|nucleotide-specific phosphatase activity|NSP I|nucleotide phosphohydrolase activity|deoxyribonucleoside-activated nucleotidase (DAN)|acid nucleotidase activity|deoxyinosine-activated nucleotidase (DIAN)											RHEA:22140|MetaCyc:NUCLEOTIDASE-RXN		molecular_function											owl:Class	
GO:0003428	biolink:NamedThing	chondrocyte intercalation involved in growth plate cartilage morphogenesis	The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone.	got7fsn_ti							dph	2009-12-22T11:52:32Z						biological_process											owl:Class	
GO:0035320	biolink:NamedThing	imaginal disc-derived wing hair site selection	Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.	got7fsn_ti	wing hair site selection|prehair localization													biological_process											owl:Class	
GO:0022606	biolink:NamedThing	establishment of proximal/distal cell polarity	The specification and formation of the polarity of a cell along its proximal/distal axis.	got7fsn_ti														biological_process											owl:Class	
GO:0033036	biolink:NamedThing	macromolecule localization	Any process in which a macromolecule is transported to, or maintained in, a specific location.	got7fsn_ti	macromolecule localisation													biological_process											owl:Class	
GO:0051179	biolink:NamedThing	localization	Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.	got7fsn_ti	establishment and maintenance of substance location|single organism localization|localisation|establishment and maintenance of position|establishment and maintenance of substrate location|establishment and maintenance of cellular component location|single-organism localization|establishment and maintenance of localization						jl	2013-12-18T13:51:04Z			GO:1902578			biological_process											owl:Class	
GO:0102832	biolink:NamedThing	verbascose galactinol:ajugose galactosyltransferase activity	Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> ajugose + myo-inositol.	got7fsn_ti												MetaCyc:RXN-8288		molecular_function											owl:Class	
GO:0061863	biolink:NamedThing	microtubule plus end polymerase	Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers.	got7fsn_ti							dph	2017-04-07T17:36:57Z						molecular_function											owl:Class	
GO:0048369	biolink:NamedThing	lateral mesoderm morphogenesis	The process in which the anatomical structures of the lateral mesoderm are generated and organized.	got7fsn_ti	lateral plate mesoderm morphogenesis													biological_process											owl:Class	
GO:0043620	biolink:NamedThing	regulation of DNA-templated transcription in response to stress	Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti	regulation of DNA-dependent transcription in response to stress													biological_process											owl:Class	
GO:0009917	biolink:NamedThing	sterol 5-alpha reductase activity	Catalysis of the removal of a C-5 double bond in the B ring of a sterol.	got7fsn_ti														molecular_function											owl:Class	
GO:0010675	biolink:NamedThing	regulation of cellular carbohydrate metabolic process	Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0006109	biolink:NamedThing	regulation of carbohydrate metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.	got7fsn_ti	regulation of carbohydrate metabolism													biological_process											owl:Class	
GO:0043603	biolink:NamedThing	cellular amide metabolic process	The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.	got7fsn_ti	amide metabolism													biological_process											owl:Class	
GO:0048890	biolink:NamedThing	lateral line ganglion development	The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.	got7fsn_ti	gLL ganglion development													biological_process											owl:Class	
GO:0061550	biolink:NamedThing	cranial ganglion development	The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.	got7fsn_ti	cranial ganglia development						dph	2013-07-10T08:40:14Z						biological_process											owl:Class	
GO:0030255	biolink:NamedThing	protein secretion by the type IV secretion system	The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system.	got7fsn_ti	type IV protein secretion system|protein secretion by the type IV protein secretion system|protein secretion by the T4SS				Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type IV protein secretion system complex ; GO:0043684'.									biological_process											owl:Class	
GO:0071806	biolink:NamedThing	protein transmembrane transport	The process in which a protein is transported across a membrane.	got7fsn_ti	protein membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-09-03T02:54:26Z						biological_process											owl:Class	
GO:0036332	biolink:NamedThing	placental growth factor-activated receptor activity	Combining with placental growth factor (PlGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	PlGF-activated receptor activity|placental growth factor receptor activity|PlGF receptor activity						bf	2012-09-05T09:34:37Z						molecular_function											owl:Class	
GO:0043452	biolink:NamedThing	cellular alkyne metabolic process	The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells.	got7fsn_ti	alkyne metabolism													biological_process											owl:Class	
GO:0044237	biolink:NamedThing	cellular metabolic process	The chemical reactions and pathways by which individual cells transform chemical substances.	got7fsn_ti	intermediary metabolism|cellular metabolism													biological_process											owl:Class	
GO:0061257	biolink:NamedThing	mesonephric glomerular visceral epithelial cell development	The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.	got7fsn_ti							dph	2010-08-30T02:10:40Z						biological_process											owl:Class	
GO:0061251	biolink:NamedThing	mesonephric glomerular epithelial cell development	The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.	got7fsn_ti							dph	2010-08-30T01:20:45Z						biological_process											owl:Class	
GO:0009748	biolink:NamedThing	hexokinase-independent signaling	A series of molecular signals mediated by hexose and independent of hexokinase.	got7fsn_ti	hexokinase-independent signalling													biological_process											owl:Class	
GO:0034042	biolink:NamedThing	5-formyluracil DNA N-glycosylase activity	Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.	got7fsn_ti	5-foU DNA N-glycosylase activity													molecular_function											owl:Class	
GO:0000703	biolink:NamedThing	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity	Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.	got7fsn_ti	endonuclease III|endonuclease VIII activity|DNA glycosylase/beta-lyase|endodeoxyribonuclease III|bifunctional DNA glycosylase|DNA glycosylase/AP-lyase|pyrimidine-specific oxidized base lesion DNA N-glycosylase activity|oxidized pyrimidine base lesion DNA N-glycosylase activity				Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'.						GO:0019004	Reactome:R-HSA-110227|Reactome:R-HSA-110226|Reactome:R-HSA-110224		molecular_function											owl:Class	
GO:0098631	biolink:NamedThing	cell adhesion mediator activity	The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface, to mediate adhesion of the cell to the external substrate or to another cell.	got7fsn_ti	cell adhesion molecule|protein binding involved in cell adhesion													molecular_function											owl:Class	
GO:0018837	biolink:NamedThing	2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity	Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate.	got7fsn_ti												UM-BBD_reactionID:r0502		molecular_function											owl:Class	
GO:0052692	biolink:NamedThing	raffinose alpha-galactosidase activity	Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose.	got7fsn_ti	alkaline alpha-galactosidase activity|raffinose-specific alkaline alpha-galactosidase activity|raffinose galactohydrolase activity											MetaCyc:RXN-11502|KEGG_REACTION:R01103|EC:3.2.1.22		molecular_function											owl:Class	
GO:0004557	biolink:NamedThing	alpha-galactosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase.	got7fsn_ti	melibiase activity|alpha-D-galactoside galactohydrolase activity|alpha-galactoside galactohydrolase activity|alpha-D-galactosidase activity|alpha-galactosidase A											MetaCyc:ALPHAGALACTOSID-RXN|Reactome:R-HSA-1605736|RHEA:28663|EC:3.2.1.22		molecular_function											owl:Class	
GO:0003991	biolink:NamedThing	acetylglutamate kinase activity	Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate.	got7fsn_ti	N-acetylglutamate phosphokinase activity|acetylglutamate phosphokinase activity|N-acetylglutamate 5-phosphotransferase activity|N-acetylglutamic 5-phosphotransferase activity|ATP:N-acetyl-L-glutamate 5-phosphotransferase activity|N-acetylglutamate kinase activity											RHEA:14629|EC:2.7.2.8|MetaCyc:ACETYLGLUTKIN-RXN		molecular_function											owl:Class	
GO:0045018	biolink:NamedThing	retrograde transport, vacuole to Golgi	The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment.	got7fsn_ti	retrograde transport from the vacuole													biological_process											owl:Class	
GO:0007034	biolink:NamedThing	vacuolar transport	The directed movement of substances into, out of or within a vacuole.	got7fsn_ti														biological_process											owl:Class	
GO:0090587	biolink:NamedThing	protein-phosphocysteine-glucosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0007271	biolink:NamedThing	synaptic transmission, cholinergic	The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	got7fsn_ti	cholinergic synaptic transmission													biological_process											owl:Class	
GO:0004686	biolink:NamedThing	elongation factor-2 kinase activity	Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.	got7fsn_ti	eEF-2 kinase activity|calmodulin-dependent protein kinase III activity|eEF2 kinase activity|ATP:elongation factor 2 phosphotransferase activity|CaM kinase III activity|eEF2K|STK19|elongation factor 2 kinase activity|eukaryotic elongation factor 2 kinase activity|Ca/CaM-kinase III activity|EF2K											EC:2.7.11.20|RHEA:21436|MetaCyc:2.7.11.20-RXN		molecular_function											owl:Class	
GO:0042316	biolink:NamedThing	penicillin metabolic process	The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus.	got7fsn_ti	penicillin metabolism													biological_process											owl:Class	
GO:0048621	biolink:NamedThing	post-embryonic digestive tract morphogenesis	The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.	got7fsn_ti	post-embryonic gut morphogenesis													biological_process											owl:Class	
GO:1990003	biolink:NamedThing	inosine-diphosphatase activity	Catalysis of the reaction: IDP + H2O = IMP + phosphate.	got7fsn_ti	inosine diphosphatase activity|IDP phosphatase activity|inosine-diphosphatase activity|IDPase activity						jl	2012-12-05T16:46:52Z			GO:0090450	Reactome:R-HSA-2509816|EC:3.6.1.64|RHEA:35207		molecular_function											owl:Class	
GO:0098519	biolink:NamedThing	nucleotide phosphatase activity, acting on free nucleotides	Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate.	got7fsn_ti	nucleotide phosphatase activity				To be used for NTP->NDP or NDP -> NMP. For nucleotide -> nucleoside (all phosphates removed) use nucleotidase.		dos	2013-09-26T11:04:45Z						molecular_function											owl:Class	
GO:0016417	biolink:NamedThing	S-acyltransferase activity	Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0032024	biolink:NamedThing	positive regulation of insulin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.	got7fsn_ti	up regulation of insulin secretion|activation of insulin secretion|upregulation of insulin secretion|stimulation of insulin secretion|up-regulation of insulin secretion													biological_process											owl:Class	
GO:0090277	biolink:NamedThing	positive regulation of peptide hormone secretion	Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.	got7fsn_ti							tb	2010-02-05T02:56:39Z						biological_process											owl:Class	
GO:0048521	biolink:NamedThing	negative regulation of behavior	Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.	got7fsn_ti	inhibition of behavior|down regulation of behavior|down-regulation of behavior|downregulation of behavior													biological_process											owl:Class	
GO:0031126	biolink:NamedThing	sno(s)RNA 3'-end processing	Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea.	got7fsn_ti	sno(s)RNA 3' end processing|sRNA 3'-end processing|snoRNA 3'-end processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0043144	biolink:NamedThing	sno(s)RNA processing	Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0018044	biolink:NamedThing	C-terminal peptidyl-leucine amidation	The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0091		biological_process											owl:Class	
GO:0009501	biolink:NamedThing	amyloplast	A plastid whose main function is to synthesize and store starch.	got7fsn_ti												Wikipedia:Amyloplast		cellular_component											owl:Class	
GO:0009536	biolink:NamedThing	plastid	Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.	got7fsn_ti												Wikipedia:Plastid		cellular_component											owl:Class	
GO:0050046	biolink:NamedThing	delta7-sterol 5(6)-desaturase activity	Catalysis of the reaction: a delta(7)-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ -> a delta(5,7)-sterol + 2 ferricytochrome b5 + 2 H2O.	got7fsn_ti	delta7-sterol-C5(6)-desaturase activity|lathosterol 5-desaturase activity|delta7-sterol 5-desaturase activity|delta7-sterol delta5-dehydrogenase activity|lathosterol oxidase activity|5-DES	https://github.com/geneontology/go-ontology/issues/21133										EC:1.14.19.20|RHEA:46556|MetaCyc:1.14.21.6-RXN		molecular_function											owl:Class	
GO:0033291	biolink:NamedThing	eukaryotic 80S initiation complex	A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.	got7fsn_ti														cellular_component											owl:Class	
GO:0070992	biolink:NamedThing	translation initiation complex	A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.	got7fsn_ti							mah	2009-10-30T01:23:52Z						cellular_component											owl:Class	
GO:0071177	biolink:NamedThing	MAML2-RBP-Jkappa-ICN3 complex	A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML2-RBP-Jkappa-Notch3 complex						mah	2009-11-23T02:48:56Z						cellular_component											owl:Class	
GO:0001695	biolink:NamedThing	histamine catabolic process	The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	got7fsn_ti	histamine degradation|histamine breakdown|histamine catabolism													biological_process											owl:Class	
GO:0042135	biolink:NamedThing	neurotransmitter catabolic process	The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.	got7fsn_ti	neurotransmitter breakdown|neurotransmitter degradation|neurotransmitter catabolism													biological_process											owl:Class	
GO:0036364	biolink:NamedThing	transforming growth factor beta1 activation	The release of transforming growth factor beta1 (TGF-beta1) from its latent state.	got7fsn_ti	TGFbeta 1 activation|L-TGF-beta 1 activation|TGFB1 activation|latent-TGF-beta1 activation|transforming growth factor-beta1 activation|TGF-beta 1 activation						bf	2012-09-24T10:09:02Z						biological_process											owl:Class	
GO:0036363	biolink:NamedThing	transforming growth factor beta activation	The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms.	got7fsn_ti	TGF-beta activation|L-TGF-beta activation|TGFB activation|latent TGF-beta activation|TGFbeta activation|TGF-B activation						bf	2012-09-24T10:06:56Z						biological_process											owl:Class	
GO:0036408	biolink:NamedThing	histone acetyltransferase activity (H3-K14 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K14 specific)						bf	2013-08-21T10:03:10Z						molecular_function											owl:Class	
GO:0007491	biolink:NamedThing	sternite morphogenesis	The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment.	got7fsn_ti														biological_process											owl:Class	
GO:0061232	biolink:NamedThing	mesonephric glomerular epithelium development	The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.	got7fsn_ti							dph	2010-08-19T02:49:46Z						biological_process											owl:Class	
GO:0072163	biolink:NamedThing	mesonephric epithelium development	The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	got7fsn_ti							mah	2010-02-26T01:40:43Z						biological_process											owl:Class	
GO:0097291	biolink:NamedThing	renal phosphate ion absorption	A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	got7fsn_ti	renal phosphate absorption						pr	2012-04-25T03:34:48Z						biological_process											owl:Class	
GO:0070293	biolink:NamedThing	renal absorption	A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).	got7fsn_ti	nephron absorption|renal reabsorption													biological_process											owl:Class	
GO:0003019	biolink:NamedThing	central nervous system control of baroreceptor feedback	The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.	got7fsn_ti														biological_process											owl:Class	
GO:0140644	biolink:NamedThing	neutrophil extracellular trap	Extracellular microbicidal structure composed of nuclear chromatin, histones and granular antimicrobial proteins. Histones and several neutrophil granule proteins associated with the DNA framework damage entrapped microorganisms.	got7fsn_ti	NET	https://github.com/geneontology/go-ontology/issues/21416					pg	2021-05-12T07:03:05Z						cellular_component											owl:Class	
GO:0043264	biolink:NamedThing	extracellular non-membrane-bounded organelle	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.	got7fsn_ti	extracellular non-membrane-enclosed organelle													cellular_component											owl:Class	
GO:0045995	biolink:NamedThing	regulation of embryonic development	Any process that modulates the frequency, rate or extent of embryonic development.	got7fsn_ti														biological_process											owl:Class	
GO:0047826	biolink:NamedThing	D-lysine 5,6-aminomutase activity	Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate.	got7fsn_ti	adenosylcobalamin-dependent D-lysine 5,6-aminomutase activity|D-alpha-lysine mutase activity|D-2,6-diaminohexanoate 5,6-aminomutase activity											KEGG_REACTION:R02852|EC:5.4.3.4|MetaCyc:D-LYSINE-56-AMINOMUTASE-RXN|RHEA:18241		molecular_function											owl:Class	
GO:0016869	biolink:NamedThing	intramolecular transferase activity, transferring amino groups	Catalysis of the transfer of an amino group from one position to another within a single molecule.	got7fsn_ti												EC:5.4.3.-		molecular_function											owl:Class	
GO:0035472	biolink:NamedThing	choriogonadotropin hormone receptor activity	Combining with the choriogonadotropin hormone to initiate a change in cell activity.	got7fsn_ti	CG receptor activity|chorionic gonadotropin hormone receptor|chorio-gonadotrophin receptor activity						bf	2010-04-22T04:49:57Z						molecular_function											owl:Class	
GO:0016500	biolink:NamedThing	protein-hormone receptor activity	Combining with a protein hormone to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0045038	biolink:NamedThing	protein import into chloroplast thylakoid membrane	The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma.	got7fsn_ti	protein transport into chloroplast thylakoid membrane|chloroplast thylakoid membrane protein import													biological_process											owl:Class	
GO:0006612	biolink:NamedThing	protein targeting to membrane	The process of directing proteins towards a membrane, usually using signals contained within the protein.	got7fsn_ti	protein-membrane targeting|protein membrane targeting													biological_process											owl:Class	
GO:0047110	biolink:NamedThing	phenylglyoxylate dehydrogenase (acylating) activity	Catalysis of the reaction: CoA + NAD(+) + phenylglyoxylate = benzoyl-CoA + CO(2) + NADH.	got7fsn_ti	phenylglyoxylate:NAD+ oxidoreductase activity											EC:1.2.1.58|KEGG_REACTION:R02450|RHEA:10372|MetaCyc:1.2.1.58-RXN		molecular_function											owl:Class	
GO:0043364	biolink:NamedThing	glycyl-radical enzyme activating activity	Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).	got7fsn_ti	catalysis of free radical formation	https://github.com/geneontology/go-ontology/issues/14190										EC:1.97.1.-		molecular_function											owl:Class	
GO:0075522	biolink:NamedThing	IRES-dependent viral translational initiation	Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation.	got7fsn_ti							jl	2011-08-03T02:25:03Z				VZ:867		biological_process											owl:Class	
GO:1905555	biolink:NamedThing	positive regulation of blood vessel branching	Any process that activates or increases the frequency, rate or extent of blood vessel branching.	got7fsn_ti	activation of branching involved in blood vessel morphogenesis|up regulation of branching involved in blood vessel morphogenesis|positive regulation of branching involved in blood vessel morphogenesis|upregulation of branching involved in blood vessel morphogenesis|activation of patterning of blood vessels|up-regulation of patterning of blood vessels|upregulation of patterning of blood vessels|up regulation of patterning of blood vessels|up-regulation of branching involved in blood vessel morphogenesis						nc	2016-10-12T14:19:49Z						biological_process											owl:Class	
GO:1905553	biolink:NamedThing	regulation of blood vessel branching	Any process that modulates the frequency, rate or extent of blood vessel branching.	got7fsn_ti	regulation of branching involved in blood vessel morphogenesis						nc	2016-10-12T14:19:33Z						biological_process											owl:Class	
GO:0052829	biolink:NamedThing	inositol-1,3,4-trisphosphate 1-phosphatase activity	Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.	got7fsn_ti							ai	2011-11-29T09:58:00Z				Reactome:R-HSA-1855232		molecular_function											owl:Class	
GO:0046030	biolink:NamedThing	inositol trisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate.	got7fsn_ti	inositol-1,4,5-trisphosphate phosphatase|IP3 phosphatase activity|IP(3) phosphatase activity													molecular_function											owl:Class	
GO:0007437	biolink:NamedThing	adult salivary gland morphogenesis	The process in which the anatomical structures of the adult salivary gland are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0007435	biolink:NamedThing	salivary gland morphogenesis	The process in which the anatomical structures of the salivary gland are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0044497	biolink:NamedThing	positive regulation of blood pressure in other organism	A process by which one organism increases the force with which blood travels through the circulatory system of another organism.	got7fsn_ti							jl	2012-02-01T02:17:21Z						biological_process											owl:Class	
GO:0045777	biolink:NamedThing	positive regulation of blood pressure	Any process in which the force of blood traveling through the circulatory system is increased.	got7fsn_ti	up-regulation of blood pressure|up regulation of blood pressure|upregulation of blood pressure|activation of blood pressure|stimulation of blood pressure													biological_process											owl:Class	
GO:0061429	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by oleic acid	Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti							dph	2012-02-07T09:54:49Z						biological_process											owl:Class	
GO:0003071	biolink:NamedThing	renal system process involved in regulation of systemic arterial blood pressure	Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.	got7fsn_ti	renal control of blood pressure|renal regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0052727	biolink:NamedThing	capsanthin synthase activity	Catalysis of the reaction: antheraxanthin = capsanthin.	got7fsn_ti	ketoxanthophyll synthase activity|capsanthin-capsorubin synthase activity|CCS						ai	2011-08-16T03:09:21Z				MetaCyc:RXN-7947|EC:5.3.99.8|RHEA:17373		molecular_function											owl:Class	
GO:0070137	biolink:NamedThing	ubiquitin-like protein-specific endopeptidase activity	Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).	got7fsn_ti	small conjugating protein-specific endopeptidase activity													molecular_function											owl:Class	
GO:0004197	biolink:NamedThing	cysteine-type endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	got7fsn_ti	lysosomal cysteine-type endopeptidase|metacaspase activity|caspase activity|thiol endopeptidase activity											Reactome:R-HSA-201595|Reactome:R-HSA-2028697|Reactome:R-HSA-211190|MetaCyc:3.4.22.27-RXN|Reactome:R-HSA-201611|Reactome:R-HSA-2562564|Reactome:R-HSA-5660663|Reactome:R-HSA-201639|Reactome:R-HSA-139952|Reactome:R-HSA-9684273|Reactome:R-HSA-418852|Reactome:R-HSA-264871|Reactome:R-HSA-5634228|Reactome:R-HSA-351913|Reactome:R-HSA-201637|Reactome:R-HSA-9694625|Reactome:R-HSA-139898|Reactome:R-HSA-418846|Reactome:R-HSA-9694377|Reactome:R-HSA-202969|Reactome:R-HSA-114252|EC:3.4.22.8|Reactome:R-HSA-211651|EC:3.4.22.-|Reactome:R-HSA-351894|Reactome:R-HSA-202967|Reactome:R-HSA-350319|Reactome:R-HSA-201640|Reactome:R-HSA-933532|Reactome:R-HSA-2130336|MetaCyc:3.4.22.15-RXN|Reactome:R-HSA-9012556|Reactome:R-HSA-9684309|Reactome:R-HSA-351877|Reactome:R-HSA-9684351|Reactome:R-HSA-5357828|Reactome:R-HSA-1678981|EC:3.4.22.41|Reactome:R-HSA-114259|MetaCyc:3.4.22.40-RXN|Reactome:R-HSA-2130706|MetaCyc:3.4.22.14-RXN|Reactome:R-HSA-418845|EC:3.4.22.14|Reactome:R-HSA-9684340|Reactome:R-HSA-352268|Reactome:R-HSA-350318|MetaCyc:3.4.22.16-RXN|Reactome:R-HSA-9603534|Reactome:R-HSA-9686930|Reactome:R-HSA-202939|Reactome:R-HSA-201608|Reactome:R-HSA-2130504|Reactome:R-HSA-2130349|Reactome:R-HSA-350651|Reactome:R-HSA-9684336|EC:3.4.22.38|Reactome:R-HSA-351876|Reactome:R-HSA-212552|Reactome:R-HSA-6814387|Reactome:R-HSA-351901|Reactome:R-HSA-448703|Reactome:R-HSA-202960|Reactome:R-HSA-202947|Reactome:R-HSA-5682377|Reactome:R-HSA-351849|Reactome:R-HSA-211186|Reactome:R-HSA-5681987|MetaCyc:3.4.22.38-RXN|MetaCyc:3.4.22.41-RXN|Reactome:R-HSA-1678920|Reactome:R-HSA-9013895|Reactome:R-HSA-1236948|Reactome:R-HSA-9694551|EC:3.4.22.15|Reactome:R-HSA-351871|Reactome:R-HSA-202917|Reactome:R-HSA-9694732|Reactome:R-HSA-201631|Reactome:R-HSA-201634|Reactome:R-HSA-202966|Reactome:R-HSA-201636|Reactome:R-HSA-3465448|EC:3.4.22.34|Reactome:R-HSA-201628|Reactome:R-HSA-351936|EC:3.4.22.28|Reactome:R-HSA-9694601|Reactome:R-HSA-201630|Reactome:R-HSA-9684352|MetaCyc:3.4.22.34-RXN|EC:3.4.22.1|Reactome:R-HSA-201603|Reactome:R-HSA-201622|Reactome:R-HSA-9697750|EC:3.4.22.40|Reactome:R-HSA-114261|Reactome:R-HSA-9684321|Reactome:R-HSA-9694338|Reactome:R-HSA-201629|Reactome:R-HSA-9693929|Reactome:R-HSA-264865|Reactome:R-HSA-350158|Reactome:R-HSA-9647999|Reactome:R-HSA-2028692|EC:3.4.22.27|Reactome:R-HSA-9694441|EC:3.4.22.16|MetaCyc:3.4.22.1-RXN		molecular_function											owl:Class	
GO:0031720	biolink:NamedThing	haptoglobin binding	Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0080030	biolink:NamedThing	methyl indole-3-acetate esterase activity	Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+.	got7fsn_ti	indole-3-Acetic acid methyl ester esterase activity|MeIAA esterase activity|methyl indole-3-acetate esterase activity|Methyl IAA esterase activity											EC:3.1.1.1|MetaCyc:RXN-10711		molecular_function											owl:Class	
GO:0047479	biolink:NamedThing	trypanothione synthase activity	Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate.	got7fsn_ti	TSR synthetase activity|glutathionylspermidine:glutathione ligase (ADP-forming)											MetaCyc:6.3.1.9-RXN|EC:6.3.1.9|RHEA:21532		molecular_function											owl:Class	
GO:0070581	biolink:NamedThing	rolling circle DNA replication	A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.	got7fsn_ti	rolling circle replication						mah	2009-04-22T02:53:52Z						biological_process											owl:Class	
GO:0006261	biolink:NamedThing	DNA-dependent DNA replication	A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.	got7fsn_ti											GO:0006262|GO:0006263			biological_process											owl:Class	
GO:0030599	biolink:NamedThing	pectinesterase activity	Catalysis of the reaction: pectin + n H2O = n methanol + pectate.	got7fsn_ti	pectin pectylhydrolase activity|pectase activity|pectin methoxylase activity|pectin demethoxylase activity|pectin methylesterase activity|pectinoesterase activity|pectin methyl esterase activity											MetaCyc:PECTINESTERASE-RXN|RHEA:22380|EC:3.1.1.11		molecular_function											owl:Class	
GO:0042668	biolink:NamedThing	auditory receptor cell fate determination	The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	auditory hair cell fate determination													biological_process											owl:Class	
GO:1901566	biolink:NamedThing	organonitrogen compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organonitrogen compound.	got7fsn_ti	organonitrogen compound biosynthesis|organonitrogen compound synthesis|organonitrogen compound formation|organonitrogen compound anabolism						pr	2012-11-04T15:18:00Z						biological_process											owl:Class	
GO:0080148	biolink:NamedThing	negative regulation of response to water deprivation	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.	got7fsn_ti							dhl	2010-03-26T01:58:11Z						biological_process											owl:Class	
GO:0047998	biolink:NamedThing	hyoscyamine (6S)-dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O(2) = (6S)-6-hydroxyhyoscyamine + CO(2) + succinate.	got7fsn_ti	hyoscyamine 6-beta-hydroxylase activity|hyoscyamine (6S)-hydroxylase activity|hyoscyamine 6-hydroxylase activity|hyoscyamine 6beta-hydroxylase activity|L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)|hyoscyamine 6beta-dioxygenase activity											MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN|RHEA:12629|EC:1.14.11.11|KEGG_REACTION:R03812		molecular_function											owl:Class	
GO:0036466	biolink:NamedThing	synaptic vesicle recycling via endosome	Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate.	got7fsn_ti	recycling endosome localization within postsynapse						bf	2014-06-26T11:07:46Z			GO:0099090			biological_process											owl:Class	
GO:0036465	biolink:NamedThing	synaptic vesicle recycling	The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane.	got7fsn_ti	kiss-and-stay synaptic vesicle recycling|kiss-and-run synaptic vesicle recycling						bf	2014-06-26T11:03:08Z						biological_process											owl:Class	
GO:0006473	biolink:NamedThing	protein acetylation	The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti	protein amino acid acetylation													biological_process											owl:Class	
GO:0008387	biolink:NamedThing	steroid 7-alpha-hydroxylase activity	Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O.	got7fsn_ti	cytochrome P450 CYP2A12													molecular_function											owl:Class	
GO:0021674	biolink:NamedThing	rhombomere 8 morphogenesis	The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0021593	biolink:NamedThing	rhombomere morphogenesis	The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.	got7fsn_ti														biological_process											owl:Class	
GO:0014812	biolink:NamedThing	muscle cell migration	The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.	got7fsn_ti														biological_process											owl:Class	
GO:0003009	biolink:NamedThing	skeletal muscle contraction	A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.	got7fsn_ti														biological_process											owl:Class	
GO:0006941	biolink:NamedThing	striated muscle contraction	A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.	got7fsn_ti	sarcomeric muscle contraction													biological_process											owl:Class	
GO:0008091	biolink:NamedThing	spectrin	Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.	got7fsn_ti												NIF_Subcellular:sao536287099|Wikipedia:Spectrin		cellular_component											owl:Class	
GO:0060523	biolink:NamedThing	prostate epithelial cord elongation	The developmental growth process in which solid chords of prostate epithelium increase in length.	got7fsn_ti														biological_process											owl:Class	
GO:2001136	biolink:NamedThing	negative regulation of endocytic recycling	Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling.	got7fsn_ti	negative regulation of retrograde transport of endocytic vesicles						kmv	2011-10-14T03:34:43Z						biological_process											owl:Class	
GO:0042710	biolink:NamedThing	biofilm formation	A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17727												biological_process											owl:Class	
GO:0106217	biolink:NamedThing	tRNA C3-cytosine methylation	The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine.	got7fsn_ti							hjd	2019-07-19T19:52:40Z						biological_process											owl:Class	
GO:0036038	biolink:NamedThing	MKS complex	A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane.	got7fsn_ti	tectonic complex|MKS module|B9 complex|TCTN-B9D complex|tectonic-like complex				Although there is some evidence, it is still unclear if the MKS and NPHP complexes are constituents parts of the Y-shaped links or are simply responsible for aligning and attaching the Y-shaped links to the membrane and axoneme.		bf	2011-11-22T11:21:28Z						cellular_component											owl:Class	
GO:0060303	biolink:NamedThing	regulation of nucleosome density	Any process that modulates the number of nucleosomes in a given region of a chromosome.	got7fsn_ti														biological_process											owl:Class	
GO:0048859	biolink:NamedThing	formation of anatomical boundary	The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	got7fsn_ti														biological_process											owl:Class	
GO:0048442	biolink:NamedThing	sepal development	The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.	got7fsn_ti											GO:0048421			biological_process											owl:Class	
GO:0048437	biolink:NamedThing	floral organ development	The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.	got7fsn_ti											GO:0048433			biological_process											owl:Class	
GO:0018175	biolink:NamedThing	protein nucleotidylation	The addition of a nucleotide to a protein amino acid.	got7fsn_ti	protein amino acid nucleotidylation													biological_process											owl:Class	
GO:0047506	biolink:NamedThing	(deoxy)adenylate kinase activity	Catalysis of the reaction: ATP + dAMP = ADP + dADP.	got7fsn_ti	ATP:(d)AMP phosphotransferase activity											RHEA:23100|MetaCyc:DEOXYADENYLATE-KINASE-RXN|EC:2.7.4.11		molecular_function											owl:Class	
GO:0044094	biolink:NamedThing	host cell nuclear part	Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		jl	2009-04-22T01:59:14Z						cellular_component											owl:Class	
GO:0033646	biolink:NamedThing	host intracellular part	Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	host cell intracellular part				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									cellular_component											owl:Class	
GO:0044554	biolink:NamedThing	modulation of heart rate in other organism	Any process that modulates the frequency or rate of heart contraction of another organism.	got7fsn_ti	regulation of heart rate in other organism						jl	2012-03-29T02:59:43Z						biological_process											owl:Class	
GO:0002027	biolink:NamedThing	regulation of heart rate	Any process that modulates the frequency or rate of heart contraction.	got7fsn_ti	cardiac chronotropy|regulation of rate of heart contraction|regulation of heart contraction rate													biological_process											owl:Class	
GO:0071333	biolink:NamedThing	cellular response to glucose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.	got7fsn_ti							mah	2009-12-10T05:38:03Z						biological_process											owl:Class	
GO:0001678	biolink:NamedThing	cellular glucose homeostasis	A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment.	got7fsn_ti	cell glucose homeostasis													biological_process											owl:Class	
GO:0044267	biolink:NamedThing	cellular protein metabolic process	The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.	got7fsn_ti	cellular protein metabolism													biological_process											owl:Class	
GO:0030152	biolink:NamedThing	bacteriocin biosynthetic process	The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.	got7fsn_ti	bacteriocin formation|bacteriocin biosynthesis|bacteriocin synthesis|bacteriocin anabolism													biological_process											owl:Class	
GO:0009403	biolink:NamedThing	toxin biosynthetic process	The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.	got7fsn_ti	toxin anabolism|toxin synthesis|toxin biosynthesis|toxin formation													biological_process											owl:Class	
GO:0016418	biolink:NamedThing	S-acetyltransferase activity	Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule.	got7fsn_ti												EC:2.3.1.38		molecular_function											owl:Class	
GO:0004371	biolink:NamedThing	glycerone kinase activity	Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+).	got7fsn_ti	acetol kinase (phosphorylating)|ATP:glycerone phosphotransferase activity|dihydroxyacetone kinase activity|acetol kinase activity											RHEA:15773|KEGG_REACTION:R01011|EC:2.7.1.29|MetaCyc:GLYCERONE-KINASE-RXN		molecular_function											owl:Class	
GO:0019226	biolink:NamedThing	transmission of nerve impulse	The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.	got7fsn_ti	conduction of nerve impulse|signal transmission along a neuron													biological_process											owl:Class	
GO:0062121	biolink:NamedThing	linear element maturation	The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements.	got7fsn_ti	LinE chromosome loading|LinE focus formation						dph	2019-03-19T14:19:27Z						biological_process											owl:Class	
GO:0070192	biolink:NamedThing	chromosome organization involved in meiotic cell cycle	A process of chromosome organization that is involved in a meiotic cell cycle.	got7fsn_ti	chromosome organisation involved in meiosis|meiotic chromosome organization													biological_process											owl:Class	
GO:1990409	biolink:NamedThing	adrenomedullin binding	Binding to adrenomedullin (AM).	got7fsn_ti	AM binding				An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.		bhm	2014-07-02T14:37:19Z						molecular_function											owl:Class	
GO:0097644	biolink:NamedThing	calcitonin family binding	Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).	got7fsn_ti							pr	2014-09-08T20:50:52Z						molecular_function											owl:Class	
GO:0097387	biolink:NamedThing	capitate projection	Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies).	got7fsn_ti							pr	2012-10-22T13:57:10Z						cellular_component											owl:Class	
GO:0097386	biolink:NamedThing	glial cell projection	A prolongation or process extending from a glial cell.	got7fsn_ti	glial process|glial projection						pr	2012-10-22T13:55:54Z						cellular_component											owl:Class	
GO:0051231	biolink:NamedThing	spindle elongation	The cell cycle process in which the distance is lengthened between poles of the spindle.	got7fsn_ti														biological_process											owl:Class	
GO:0007017	biolink:NamedThing	microtubule-based process	Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0050058	biolink:NamedThing	linoleate isomerase activity	Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate.	got7fsn_ti	linoleic acid isomerase activity|linoleate delta12-cis-delta11-trans-isomerase activity											EC:5.2.1.5|KEGG_REACTION:R03627|MetaCyc:LINOLEATE-ISOMERASE-RXN|RHEA:17381		molecular_function											owl:Class	
GO:0016859	biolink:NamedThing	cis-trans isomerase activity	Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.	got7fsn_ti												EC:5.2.-.-		molecular_function											owl:Class	
GO:0047930	biolink:NamedThing	glucosaminate ammonia-lyase activity	Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3.	got7fsn_ti	glucosaminic dehydrase activity|2-amino-2-deoxy-D-gluconate ammonia-lyase activity|D-glucosaminate ammonia-lyase activity|D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming)|acetylenemonocarboxylic acid hydrase activity|aminodeoxygluconate ammonia-lyase activity|aminodeoxygluconate dehydratase activity|2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating) activity|D-glucosaminic acid dehydrase activity|D-glucosaminate dehydratase activity				Note that this function was EC:4.3.1.21.						GO:0050443	EC:4.3.1.9|RHEA:12488|MetaCyc:4.3.1.21-RXN		molecular_function											owl:Class	
GO:0016841	biolink:NamedThing	ammonia-lyase activity	Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.	got7fsn_ti												EC:4.3.1.-		molecular_function											owl:Class	
GO:0035119	biolink:NamedThing	embryonic pelvic fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0035113	biolink:NamedThing	embryonic appendage morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.	got7fsn_ti														biological_process											owl:Class	
GO:0060520	biolink:NamedThing	activation of prostate induction by androgen receptor signaling pathway	Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.	got7fsn_ti	activation of prostate induction by androgen receptor signalling pathway													biological_process											owl:Class	
GO:0030521	biolink:NamedThing	androgen receptor signaling pathway	Any series of molecular signals generated as a consequence of an androgen binding to its receptor.	got7fsn_ti	androgen receptor signalling pathway													biological_process											owl:Class	
GO:0050298	biolink:NamedThing	stizolobinate synthase activity	Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.	got7fsn_ti	3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing)											RHEA:18465|MetaCyc:STIZOLOBINATE-SYNTHASE-RXN|EC:1.13.11.30		molecular_function											owl:Class	
GO:0004496	biolink:NamedThing	mevalonate kinase activity	Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H(+).	got7fsn_ti	mevalonate 5-phosphotransferase activity|MVA kinase activity|ATP:(R)-mevalonate 5-phosphotransferase activity|mevalonate kinase (phosphorylating)|mevalonate phosphokinase activity|mevalonic kinase activity|ATP:mevalonate 5-phosphotransferase activity|mevalonic acid kinase activity											KEGG_REACTION:R02245|EC:2.7.1.36|Reactome:R-HSA-191380|MetaCyc:MEVALONATE-KINASE-RXN|RHEA:17065		molecular_function											owl:Class	
GO:0043964	biolink:NamedThing	induction by symbiont of host adenylate cyclase-mediated signal transduction	Any process in which an organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host adenylate cyclase-mediated signal transduction													biological_process											owl:Class	
GO:0031034	biolink:NamedThing	myosin filament assembly	The aggregation, arrangement and bonding together of a filament composed of myosin molecules.	got7fsn_ti	myosin polymerization													biological_process											owl:Class	
GO:0007035	biolink:NamedThing	vacuolar acidification	Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.	got7fsn_ti														biological_process											owl:Class	
GO:0051452	biolink:NamedThing	intracellular pH reduction	Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion.	got7fsn_ti	reduction of pH in cell|cellular acidification|cell pH reduction|intracellular acidification|reduction of cellular pH													biological_process											owl:Class	
GO:0002212	biolink:NamedThing	behavioral defense response to nematode	A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.	got7fsn_ti	behavioural defense response to nematode													biological_process											owl:Class	
GO:0002215	biolink:NamedThing	defense response to nematode	A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.	got7fsn_ti	physiological defense response to nematode										GO:0002216			biological_process											owl:Class	
GO:0048036	biolink:NamedThing	central complex development	The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.	got7fsn_ti	central body development													biological_process											owl:Class	
GO:0002317	biolink:NamedThing	plasma cell differentiation	The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.	got7fsn_ti	plasma cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0002313	biolink:NamedThing	mature B cell differentiation involved in immune response	The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response.	got7fsn_ti	mature B cell development involved in immune response|mature B lymphocyte differentiation during immune response|mature B cell differentiation during immune response|mature B-lymphocyte differentiation during immune response|mature B-cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0046365	biolink:NamedThing	monosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.	got7fsn_ti	monosaccharide degradation|monosaccharide catabolism|monosaccharide breakdown													biological_process											owl:Class	
GO:0035045	biolink:NamedThing	sperm plasma membrane disassembly	The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.	got7fsn_ti	sperm plasma membrane catabolism|sperm plasma membrane breakdown|sperm plasma membrane degradation													biological_process											owl:Class	
GO:0150155	biolink:NamedThing	interleukin-34 production	The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti							bc	2020-01-06T16:25:25Z						biological_process											owl:Class	
GO:0004909	biolink:NamedThing	interleukin-1, type I, activating receptor activity	Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins.	got7fsn_ti	interleukin-1 type I receptor activity|interleukin-1, type I, activating binding|interleukin-1 activating receptor activity|IL-1 type I, activating receptor|IL-1 type I, activating binding										GO:0019967			molecular_function											owl:Class	
GO:0004908	biolink:NamedThing	interleukin-1 receptor activity	Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.	got7fsn_ti	IL-1 receptor activity|IL-1R											Wikipedia:Interleukin-1_receptor		molecular_function											owl:Class	
GO:0051291	biolink:NamedThing	protein heterooligomerization	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	got7fsn_ti	protein heterooligomer biosynthesis|protein heterooligomer formation|protein heterooligomer assembly|protein heterooligomer biosynthetic process													biological_process											owl:Class	
GO:0071350	biolink:NamedThing	cellular response to interleukin-15	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.	got7fsn_ti	cellular response to IL-15						mah	2009-12-11T02:49:51Z						biological_process											owl:Class	
GO:0070672	biolink:NamedThing	response to interleukin-15	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.	got7fsn_ti	response to IL-15						mah	2009-05-29T10:03:09Z						biological_process											owl:Class	
GO:0015620	biolink:NamedThing	ferric-enterobactin transmembrane transporter activity	Enables the transfer of ferric-enterobactin from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0071340	biolink:NamedThing	skeletal muscle acetylcholine-gated channel clustering	The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.	got7fsn_ti	skeletal muscle nicotinic acetylcholine receptor clustering|skeletal muscle AChR clustering						mah	2009-12-11T11:13:55Z						biological_process											owl:Class	
GO:0015566	biolink:NamedThing	acriflavine transmembrane transporter activity	Enables the directed movement of acriflavin from one side of a membrane to the other. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.	got7fsn_ti	acriflavine transporter activity|acriflavin transporter activity|acriflavin resistant pump activity										GO:0015555			molecular_function											owl:Class	
GO:0002452	biolink:NamedThing	B cell receptor editing	The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.	got7fsn_ti	B-lymphocyte receptor editing|B lymphocyte receptor editing|B-cell receptor editing													biological_process											owl:Class	
GO:0016447	biolink:NamedThing	somatic recombination of immunoglobulin gene segments	The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.	got7fsn_ti	somatic recombination of antibody gene segments													biological_process											owl:Class	
GO:0043379	biolink:NamedThing	memory T cell differentiation	The process in which a newly activated T cell acquires specialized features of a memory T cell.	got7fsn_ti	memory T cell development|memory T-lymphocyte differentiation|memory T-cell differentiation|memory T lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0090715	biolink:NamedThing	immunological memory formation process	Any immunological memory process that can contribute to the formation of immunological memory.	got7fsn_ti							tb	2016-11-11T12:25:47Z						biological_process											owl:Class	
GO:0042022	biolink:NamedThing	interleukin-12 receptor complex	A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.	got7fsn_ti	IL12RB1-IL12RB2 complex|IL-12 receptor complex													cellular_component											owl:Class	
GO:0010460	biolink:NamedThing	positive regulation of heart rate	Any process that activates or increases the frequency or rate of heart contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0045823	biolink:NamedThing	positive regulation of heart contraction	Any process that activates or increases the frequency, rate or extent of heart contraction.	got7fsn_ti	up-regulation of heart contraction|upregulation of heart contraction|positive regulation of cardiac contraction|up regulation of heart contraction|activation of heart contraction|stimulation of heart contraction													biological_process											owl:Class	
GO:0015562	biolink:NamedThing	efflux transmembrane transporter activity	Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	efflux permease activity|monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity													molecular_function											owl:Class	
GO:0022857	biolink:NamedThing	transmembrane transporter activity	Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.	got7fsn_ti	substrate-specific transmembrane transporter activity|substrate-specific transporter activity|uptake transmembrane transporter activity|uptake permease activity										GO:0015646|GO:0005386|GO:0022892|GO:0015563|GO:0022891	Reactome:R-HSA-6784436|Reactome:R-HSA-5671707|Reactome:R-HSA-429036|Reactome:R-HSA-6784434|Reactome:R-HSA-5638209|Reactome:R-HSA-1236947		molecular_function											owl:Class	
GO:0018061	biolink:NamedThing	peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine	The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid.	got7fsn_ti	peptidyl-L-3-phenyllactic acid anabolism from peptidyl-phenylalanine|peptidyl-L-3-phenyllactic acid synthesis from peptidyl-phenylalanine|peptidyl-L-3-phenyllactic acid formation from peptidyl-phenylalanine											RESID:AA0128		biological_process											owl:Class	
GO:0045993	biolink:NamedThing	negative regulation of translational initiation by iron	Any process involving iron that stops, prevents or reduces the rate of translational initiation.	got7fsn_ti	downregulation of translational initiation by iron|down regulation of translational initiation by iron|inhibition of translational initiation by iron|down-regulation of translational initiation by iron													biological_process											owl:Class	
GO:0006447	biolink:NamedThing	regulation of translational initiation by iron	Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron.	got7fsn_ti														biological_process											owl:Class	
GO:0050563	biolink:NamedThing	trans-feruloyl-CoA synthase activity	Catalysis of the reaction: ATP + CoA + trans-ferulate = (E)-feruloyl-CoA + ADP + phosphate.	got7fsn_ti	trans-feruloyl-CoA synthetase activity|trans-ferulate:CoASH ligase (ATP-hydrolysing)|ferulate-CoA ligase activity						hjd	2020-07-30T15:20:51Z			GO:0106287	MetaCyc:6.2.1.34-RXN|RHEA:19389|EC:6.2.1.34		molecular_function											owl:Class	
GO:0005105	biolink:NamedThing	type 1 fibroblast growth factor receptor binding	Binding to a type 1 fibroblast growth factor receptor (FGFR1).	got7fsn_ti	FGFR1 ligand|breathless ligand|type 1 fibroblast growth factor receptor ligand|FGFR1 binding|breathless binding				Note that breathless is the Drosophila gene encoding the type 1 fibroblast growth factor receptor (FGFR1).									molecular_function											owl:Class	
GO:0005104	biolink:NamedThing	fibroblast growth factor receptor binding	Binding to a fibroblast growth factor receptor (FGFR).	got7fsn_ti	FGFR binding|fibroblast growth factor receptor ligand|FGFR ligand|fibroblast growth factor|FGF receptor binding				Note that branchless is the Drosophila gene encoding fibroblast growth factor.						GO:0005162|GO:0001521			molecular_function											owl:Class	
GO:0097538	biolink:NamedThing	ciliary necklace	A protein complex located on the cilium membrane in the ciliary transition zone; it is connected to the cilium axoneme via Y-shaped links.	got7fsn_ti	cilial necklace|cilium necklace						pr	2013-12-03T16:43:41Z						cellular_component											owl:Class	
GO:0050069	biolink:NamedThing	lysine dehydrogenase activity	Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH.	got7fsn_ti	L-lysine:NAD+ oxidoreductase (deaminating, cyclizing)											EC:1.4.1.15|MetaCyc:LYSINE-DEHYDROGENASE-RXN|RHEA:18505		molecular_function											owl:Class	
GO:0044634	biolink:NamedThing	negative regulation of complement activation, alternative pathway in other organism	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.	got7fsn_ti							jl	2012-07-05T04:32:55Z						biological_process											owl:Class	
GO:0044633	biolink:NamedThing	modulation of complement activation, alternative pathway in other organism	A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism.	got7fsn_ti	regulation of complement activation, alternative pathway in other organism						jl	2012-07-05T04:24:08Z						biological_process											owl:Class	
GO:1990953	biolink:NamedThing	intramanchette transport	The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments.	got7fsn_ti	IMT						krc	2016-05-11T00:17:56Z						biological_process											owl:Class	
GO:0098840	biolink:NamedThing	protein transport along microtubule	The directed movement of a protein along a microtubule, mediated by motor proteins.	got7fsn_ti	microtubule-based protein transport													biological_process											owl:Class	
GO:0102305	biolink:NamedThing	(13E)-labda-7,13-dien-15-ol synthase activity	Catalysis of the reaction: 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-12892|EC:3.1.7.10|RHEA:32075		molecular_function											owl:Class	
GO:0016794	biolink:NamedThing	diphosphoric monoester hydrolase activity	Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group.	got7fsn_ti												EC:3.1.7.-		molecular_function											owl:Class	
GO:2000146	biolink:NamedThing	negative regulation of cell motility	Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.	got7fsn_ti	negative regulation of cell movement|negative regulation of cell locomotion|negative regulation of movement of a cell						mah	2010-10-01T09:41:26Z						biological_process											owl:Class	
GO:0048851	biolink:NamedThing	hypophysis formation	The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.	got7fsn_ti	pituitary gland biosynthesis|hypophysis biosynthesis|pituitary gland formation													biological_process											owl:Class	
GO:0021725	biolink:NamedThing	superior raphe nucleus development	The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.	got7fsn_ti	anterior raphe nucleus development|superior central nucleus development													biological_process											owl:Class	
GO:0019150	biolink:NamedThing	D-ribulokinase activity	Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate.	got7fsn_ti	ATP:D-ribulose 5-phosphotransferase activity|D-ribulokinase (phosphorylating)											MetaCyc:D-RIBULOKIN-RXN|RHEA:17601|EC:2.7.1.47		molecular_function											owl:Class	
GO:0031349	biolink:NamedThing	positive regulation of defense response	Any process that activates or increases the frequency, rate or extent of a defense response.	got7fsn_ti	up regulation of defense response|upregulation of defense response|activation of defense response|up-regulation of defense response|stimulation of defense response													biological_process											owl:Class	
GO:0031347	biolink:NamedThing	regulation of defense response	Any process that modulates the frequency, rate or extent of a defense response.	got7fsn_ti														biological_process											owl:Class	
GO:0021741	biolink:NamedThing	spinal trigeminal nucleus development	The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0021730	biolink:NamedThing	trigeminal sensory nucleus development	The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure.	got7fsn_ti					Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions from midbrain to spinal cord.									biological_process											owl:Class	
GO:0008083	biolink:NamedThing	growth factor activity	The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.	got7fsn_ti					Also consider annotating to 'receptor agonist activity ; GO:0048018'.									molecular_function											owl:Class	
GO:0048018	biolink:NamedThing	receptor ligand activity	The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).	got7fsn_ti	signaling receptor ligand activity|receptor agonist activity|signaling molecule|vitamin D receptor activator activity	https://github.com/geneontology/go-ontology/issues/14220					mah	2010-09-13T04:51:59Z			GO:0071884			molecular_function											owl:Class	
GO:0020014	biolink:NamedThing	schizogony	Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.	got7fsn_ti												Wikipedia:Protozoal_merogony		biological_process											owl:Class	
GO:0090426	biolink:NamedThing	actin filament bundle convergence	A process of actin filament bundle distribution that results in the compaction of actin filaments.	got7fsn_ti							tb	2012-05-04T09:33:09Z						biological_process											owl:Class	
GO:0070650	biolink:NamedThing	actin filament bundle distribution	Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.	got7fsn_ti							mah	2009-05-12T02:20:58Z						biological_process											owl:Class	
GO:0046952	biolink:NamedThing	ketone body catabolic process	The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.	got7fsn_ti	ketone body breakdown|ketone body catabolism|utilization of ketone bodies|ketone body degradation|ketolysis											MetaCyc:PWY66-368|Reactome:R-HSA-77108		biological_process											owl:Class	
GO:0046950	biolink:NamedThing	cellular ketone body metabolic process	The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism.	got7fsn_ti	cellular ketone body metabolism													biological_process											owl:Class	
GO:1990375	biolink:NamedThing	baculum development	The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure.	got7fsn_ti	os penis development|penis bone development|penile bone development						sl	2014-05-01T23:59:13Z						biological_process											owl:Class	
GO:0072578	biolink:NamedThing	neurotransmitter-gated ion channel clustering	The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.	got7fsn_ti							mah	2011-02-03T01:45:48Z						biological_process											owl:Class	
GO:0150050	biolink:NamedThing	postsynaptic septin cytoskeleton	The portion of the septin cytoskeleton contained within the postsynapse.	got7fsn_ti							bc	2018-04-26T14:45:52Z						cellular_component											owl:Class	
GO:0004727	biolink:NamedThing	prenylated protein tyrosine phosphatase activity	Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0004725	biolink:NamedThing	protein tyrosine phosphatase activity	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	got7fsn_ti	PTP-phosphatase activity|protein-tyrosine-phosphatase activity|phosphotyrosine histone phosphatase activity|phosphoprotein phosphatase (phosphotyrosine) activity|PPT-phosphatase activity|PTPase activity|[phosphotyrosine]protein phosphatase activity|protein phosphotyrosine phosphatase activity|protein-tyrosine-phosphate phosphohydrolase activity|tyrosylprotein phosphatase activity|tyrosine O-phosphate phosphatase activity|phosphotyrosine phosphatase activity|phosphotyrosine protein phosphatase activity|phosphotyrosylprotein phosphatase activity											MetaCyc:PROTEIN-TYROSINE-PHOSPHATASE-RXN|Reactome:R-HSA-1549564|Reactome:R-HSA-8863804|Reactome:R-HSA-203797|Reactome:R-HSA-202214|Reactome:R-HSA-8852200|Reactome:R-HSA-377643|Reactome:R-HSA-914036|Reactome:R-HSA-877308|Reactome:R-HSA-445089|Reactome:R-HSA-8849435|Reactome:R-HSA-1169210|Reactome:R-HSA-6807008|Reactome:R-HSA-8864125|Reactome:R-HSA-8864029|Reactome:R-HSA-391868|RHEA:10684|Reactome:R-HSA-1169192|Reactome:R-HSA-8937767|Reactome:R-HSA-8855381|Reactome:R-HSA-1169188|Reactome:R-HSA-74733|Reactome:R-HSA-74748|Reactome:R-HSA-9635461|EC:3.1.3.48|Reactome:R-HSA-389758|Reactome:R-HSA-997311|Reactome:R-HSA-8867047|Reactome:R-HSA-74747|Reactome:R-HSA-9636439|Reactome:R-HSA-8864036|Reactome:R-HSA-8867658|Reactome:R-HSA-9603719|Reactome:R-HSA-997326|Reactome:R-HSA-9698408|Reactome:R-HSA-6807027|Reactome:R-HSA-5683967|Reactome:R-HSA-997314|Reactome:R-HSA-997309		molecular_function											owl:Class	
GO:0061519	biolink:NamedThing	macrophage homeostasis	The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti							dph	2013-04-18T13:25:33Z						biological_process											owl:Class	
GO:0005955	biolink:NamedThing	calcineurin complex	A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.	got7fsn_ti	protein phosphatase type 2B complex|calcium-dependent protein serine/threonine phosphatase complex													cellular_component											owl:Class	
GO:0033844	biolink:NamedThing	galactose-6-sulfurylase activity	Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues.	got7fsn_ti	galactose-6-sulfatase activity|D-galactose-6-sulfate:alkyltransferase (cyclizing) activity|galactose 6-sulfatase activity|porphyran sulfatase activity											MetaCyc:2.5.1.5-RXN|EC:2.5.1.5		molecular_function											owl:Class	
GO:0039630	biolink:NamedThing	RNA translocase activity	Generating a movement along a single- or double-stranded RNA molecule, driven by ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21612			Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane.		bf	2012-08-06T13:24:51Z						molecular_function											owl:Class	
GO:0008186	biolink:NamedThing	ATP-dependent activity, acting on RNA	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.	got7fsn_ti	ATPase activity, acting on RNA|RNA-dependent ATPase activity|RNA-dependent adenosinetriphosphatase activity|ATPase, acting on RNA	https://github.com/geneontology/go-ontology/issues/20876|https://github.com/geneontology/go-ontology/issues/21775									GO:0004010			molecular_function											owl:Class	
GO:0014887	biolink:NamedThing	cardiac muscle adaptation	The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.	got7fsn_ti	cardiac muscle plasticity													biological_process											owl:Class	
GO:0014888	biolink:NamedThing	striated muscle adaptation	Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.	got7fsn_ti	striated muscle plasticity													biological_process											owl:Class	
GO:0051818	biolink:NamedThing	disruption of cells of other organism involved in symbiotic interaction	A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction.	got7fsn_ti	disruption of cells of other organism during symbiotic interaction													biological_process											owl:Class	
GO:0010361	biolink:NamedThing	regulation of anion channel activity by blue light	Any process in which blue light modulates the frequency, rate or extent of anion channel activity.	got7fsn_ti	regulation by blue light of anion channel activity													biological_process											owl:Class	
GO:0010359	biolink:NamedThing	regulation of anion channel activity	Any process that modulates the frequency, rate or extent of anion channel activity.	got7fsn_ti														biological_process											owl:Class	
GO:0033024	biolink:NamedThing	mast cell apoptotic process	Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	got7fsn_ti	apoptosis of mast cells|mast cell apoptosis													biological_process											owl:Class	
GO:0033028	biolink:NamedThing	myeloid cell apoptotic process	Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.	got7fsn_ti	apoptosis of myeloid cells|myeloid cell apoptosis													biological_process											owl:Class	
GO:0102179	biolink:NamedThing	24-ethylidenelophenol 4alpha-methyl oxidase activity	Catalysis of the reaction: 24-ethylidenelophenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-11935|RHEA:59032		molecular_function											owl:Class	
GO:0106222	biolink:NamedThing	long noncoding RNA binding	Binding to a long noncoding  RNA (lncRNA).	got7fsn_ti	lncRNA binding						hjd	2019-08-27T14:52:58Z						molecular_function											owl:Class	
GO:0019959	biolink:NamedThing	interleukin-8 binding	Binding to interleukin-8.	got7fsn_ti	IL-8 binding													molecular_function											owl:Class	
GO:0019958	biolink:NamedThing	C-X-C chemokine binding	Binding to a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.	got7fsn_ti														molecular_function											owl:Class	
GO:0046962	biolink:NamedThing	sodium-transporting ATPase activity, rotational mechanism	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out), by a rotational mechanism.	got7fsn_ti	sodium transporting ATPase activity, rotational mechanism|ATP phosphohydrolase (Na+-transporting) activity|Na(+)-translocating ATPase activity|Na(+)-transporting two-sector ATPase activity|sodium-translocating F-type ATPase activity|vacuolar-type Na+-translocating ATPase|ATP synthase, sodium ion specific activity|vacuolar-type Na+-ATPase|Na+-translocating ATPase activity|sodium-transporting two-sector ATPase activity|sodium-translocating V-type ATPase activity|Na+-translocating F1Fo-ATPase|Na+-transporting two-sector ATPase	https://github.com/geneontology/go-ontology/issues/21796			Found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis; similar to EC:7.1.2.2 but pumps Na(+) rather than H(+). (Source: EC:7.2.2.1)							RHEA:58157|RHEA:58156|EC:7.2.2.1|MetaCyc:3.6.3.15-RXN		molecular_function											owl:Class	
GO:0044769	biolink:NamedThing	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism.	got7fsn_ti							jl	2013-02-20T13:41:38Z						molecular_function											owl:Class	
GO:0102920	biolink:NamedThing	acyl coenzyme A: isopenicillin N acyltransferase activity	Catalysis of the reaction: octanoyl-CoA + isopenicillin N + H2O <=> H+ + coenzyme A + penicillin K + L-2-aminoadipate.	got7fsn_ti												EC:2.3.1.164|MetaCyc:RXN-8809		molecular_function											owl:Class	
GO:0015031	biolink:NamedThing	protein transport	The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	enzyme transport										GO:0015831			biological_process											owl:Class	
GO:1990134	biolink:NamedThing	epithelial cell apoptotic process involved in palatal shelf morphogenesis	An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.	got7fsn_ti							dph	2013-06-26T11:56:00Z						biological_process											owl:Class	
GO:0060561	biolink:NamedThing	apoptotic process involved in morphogenesis	Any apoptotic process that contributes to the shaping of an anatomical structure.	got7fsn_ti	apoptosis involved in morphogenesis|apoptosis involved in development|morphogenetic apoptosis						dph	2009-04-28T09:17:27Z						biological_process											owl:Class	
GO:0006936	biolink:NamedThing	muscle contraction	A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.	got7fsn_ti												Wikipedia:Muscle_contraction		biological_process											owl:Class	
GO:1990215	biolink:NamedThing	negative regulation by symbiont of host intracellular transport	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-10T15:42:22Z						biological_process											owl:Class	
GO:0052038	biolink:NamedThing	modulation by symbiont of host intracellular transport	Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of host intracellular trafficking													biological_process											owl:Class	
GO:0035606	biolink:NamedThing	peptidyl-cysteine S-trans-nitrosylation	Transfer of a nitric oxide (NO) group from one cysteine residue to another.	got7fsn_ti	cysteine to cysteine nitrosylation|S-transnitrosylation|cysteine-to-cysteine transnitrosylation|protein-to-protein transnitrosylation						bf	2010-11-16T09:54:46Z						biological_process											owl:Class	
GO:0018119	biolink:NamedThing	peptidyl-cysteine S-nitrosylation	The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine.	got7fsn_ti	S-nitrosylation|protein S-nitrosylation											RESID:AA0230		biological_process											owl:Class	
GO:0043744	biolink:NamedThing	N2-acetyl-L-aminoadipate kinase activity	Catalysis of the reaction: ATP + N-acetyl-L-2-aminoadipate = ADP + N-acetyl-L-2-aminoadipate 6-phosphate.	got7fsn_ti	[LysW]-aminoadipate kinase|acetylaminoadipate kinase activity|N-acetylaminoadipate kinase activity|N-acetyl-L-aminoadipate 5-phosphotransferase activity										GO:0043868	RHEA:41944|MetaCyc:RXN-5182		molecular_function											owl:Class	
GO:0016774	biolink:NamedThing	phosphotransferase activity, carboxyl group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor).	got7fsn_ti												EC:2.7.2.-		molecular_function											owl:Class	
GO:0017198	biolink:NamedThing	N-terminal peptidyl-serine acetylation	The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine.	got7fsn_ti												RESID:AA0051		biological_process											owl:Class	
GO:0019970	biolink:NamedThing	interleukin-11 binding	Binding to interleukin-11.	got7fsn_ti	IL-11 binding													molecular_function											owl:Class	
GO:0009978	biolink:NamedThing	allene oxide synthase activity	Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O.	got7fsn_ti	linoleate hydroperoxide isomerase|HPI|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]|linoleic acid hydroperoxide isomerase											RHEA:25074|MetaCyc:RXN1F-19		molecular_function											owl:Class	
GO:0045199	biolink:NamedThing	maintenance of epithelial cell apical/basal polarity	The maintenance of the apicobasal polarity of an epithelial cell.	got7fsn_ti														biological_process											owl:Class	
GO:0035090	biolink:NamedThing	maintenance of apical/basal cell polarity	Retaining the established polarization of a cell along its apical/basal axis.	got7fsn_ti														biological_process											owl:Class	
GO:0039011	biolink:NamedThing	pronephric proximal tubule morphogenesis	The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.	got7fsn_ti	pronephros proximal tubule morphogenesis						bf	2010-07-02T09:53:12Z						biological_process											owl:Class	
GO:0072158	biolink:NamedThing	proximal tubule morphogenesis	The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.	got7fsn_ti							mah	2010-02-24T02:35:36Z						biological_process											owl:Class	
GO:0106294	biolink:NamedThing	NADPH oxidase H202-forming activity	Catalysis of the reaction: NADPH + H+ + O2 = NADP + hydrogen peroxide (H2O2).	got7fsn_ti							hjd	2020-08-19T17:38:36Z				RHEA:11260		molecular_function											owl:Class	
GO:0016174	biolink:NamedThing	NAD(P)H oxidase H2O2-forming activity	Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide.	got7fsn_ti	NAD(P)H:oxygen oxidoreductase activity|dual oxidase activity|p138tox|thyroid oxidase activity|thyroid NADPH oxidase activity|THOX2 activity|thyroid oxidase 2 activity|NAD(P)H oxidase activity|NADPH oxidase|ThOX activity											EC:1.6.3.1|Reactome:R-HSA-9698758|Reactome:R-HSA-5693681		molecular_function											owl:Class	
GO:1990401	biolink:NamedThing	embryonic lung development	The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure.	got7fsn_ti							sl	2014-06-23T19:56:13Z						biological_process											owl:Class	
GO:1900600	biolink:NamedThing	endocrocin metabolic process	The chemical reactions and pathways involving endocrocin.	got7fsn_ti	endocrocin metabolism						di	2012-05-15T06:57:14Z						biological_process											owl:Class	
GO:0106372	biolink:NamedThing	primary fluorescent dioxobilin-type chlorophyll catabolite methylesterase activity	Catalysis of the reaction: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H+ + methanol + O13(4)-desmethyl pFCC.	got7fsn_ti							hjd	2021-04-01T16:53:38Z						molecular_function											owl:Class	
GO:0000752	biolink:NamedThing	agglutination involved in conjugation with cellular fusion	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae.	got7fsn_ti	agglutination|cell-cell adhesion during mating|cell-cell adhesion during conjugation with cellular fusion										GO:0007334			biological_process											owl:Class	
GO:0000771	biolink:NamedThing	agglutination involved in conjugation	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions prior to the formation of irreversible cellular contacts during conjugation.	got7fsn_ti														biological_process											owl:Class	
GO:0030638	biolink:NamedThing	polyketide metabolic process	The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.	got7fsn_ti	polyketide metabolism													biological_process											owl:Class	
GO:0106302	biolink:NamedThing	arachidonic acid 8,9-epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-8,9-epoxyeicosatrienoic acid.	got7fsn_ti							hjd	2020-08-28T19:10:07Z				RHEA:64984		molecular_function											owl:Class	
GO:0001984	biolink:NamedThing	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure	An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure.	got7fsn_ti	vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure													biological_process											owl:Class	
GO:0038160	biolink:NamedThing	CXCL12-activated CXCR4 signaling pathway	A series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CXCL12-activated CXCR4 signalling pathway						bf	2012-05-14T01:33:17Z						biological_process											owl:Class	
GO:0038146	biolink:NamedThing	chemokine (C-X-C motif) ligand 12 signaling pathway	A series of molecular signals initiated by the binding of the chemokine CXCL12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CXCL12-activated CXCR7 signaling pathway|CXCL12 signaling pathway|stromal cell-derived factor-1 signaling pathway|SDF1 signaling pathway						bf	2012-05-11T11:26:17Z						biological_process											owl:Class	
GO:0030172	biolink:NamedThing	troponin C binding	Binding to troponin C, the calcium-binding subunit of the troponin complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0034557	biolink:NamedThing	2-hydroxylaminobenzoate reductase activity	Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O.	got7fsn_ti	o-hydroxylaminobenzoate nitroreductase activity											UM-BBD_reactionID:r0850|MetaCyc:RXN-8848		molecular_function											owl:Class	
GO:0038095	biolink:NamedThing	Fc-epsilon receptor signaling pathway	A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.	got7fsn_ti	Fc-epsilon receptor signalling pathway						bf	2012-02-16T05:23:51Z						biological_process											owl:Class	
GO:0038093	biolink:NamedThing	Fc receptor signaling pathway	A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.	got7fsn_ti	Fc receptor signalling pathway						bf	2012-02-16T05:11:30Z						biological_process											owl:Class	
GO:0007536	biolink:NamedThing	activation of recombination (HML)	The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.	got7fsn_ti														biological_process											owl:Class	
GO:0045911	biolink:NamedThing	positive regulation of DNA recombination	Any process that activates or increases the frequency, rate or extent of DNA recombination.	got7fsn_ti	stimulation of DNA recombination|up regulation of DNA recombination|upregulation of DNA recombination|activation of DNA recombination|up-regulation of DNA recombination													biological_process											owl:Class	
GO:0034292	biolink:NamedThing	pinholin activity	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall.	got7fsn_ti														molecular_function											owl:Class	
GO:0030324	biolink:NamedThing	lung development	The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.	got7fsn_ti														biological_process											owl:Class	
GO:0003876	biolink:NamedThing	AMP deaminase activity	Catalysis of the reaction: AMP + H2O = IMP + NH3.	got7fsn_ti	adenosine 5-monophosphate deaminase activity|AMP aminase activity|adenylic deaminase activity|adenosine 5-phosphate aminohydrolase activity|adenylate aminohydrolase activity|adenylate desaminase activity|adenylic acid deaminase activity|adenyl deaminase activity|adenosine monophosphate deaminase activity|adenylate deaminase reaction|AMP aminohydrolase activity|adenylate deaminase activity|5-AMP deaminase activity|5-adenylate deaminase activity|5-adenylic acid deaminase activity|myoadenylate deaminase activity											RHEA:14777|EC:3.5.4.6|MetaCyc:AMP-DEAMINASE-RXN|Reactome:R-HSA-76590		molecular_function											owl:Class	
GO:0140320	biolink:NamedThing	PAMP receptor decoy activity	A gene product which recognizes, binds and sequesters PAMP ligands in order to prevent them from binding and activating to the host PAMP receptor. Usually this activity is encoded by a symbiont or a pathogen to prevent activation of the host innate immune response.	got7fsn_ti	pattern recognition receptor decoy activity|pathogen-associated molecular pattern receptor decoy activity						pg	2019-04-02T11:07:13Z						molecular_function											owl:Class	
GO:0140319	biolink:NamedThing	receptor decoy activity	Recognizing, binding and sequestering a specific receptor ligand to prevent it from binding to its regular receptor.	got7fsn_ti	decoy receptor|decoy death receptor activity						pg	2019-04-02T10:57:46Z			GO:0005040			molecular_function											owl:Class	
GO:0072550	biolink:NamedThing	triferuloylspermidine meta-hydroxylase activity	Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O.	got7fsn_ti	triferuloyl spermidine meta-hydroxylase activity						mah	2011-01-25T02:58:56Z				MetaCyc:RXN-11262		molecular_function											owl:Class	
GO:0072532	biolink:NamedThing	tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity	Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives.	got7fsn_ti					Note that the overall reaction representing three successive executions of this activity is N1,N5,N10-triferuloyl spermidine + 3 NADPH + 3 O2 = N1,N5,N10-tri-(hydroxyferuloyl)-spermidine + 3 NADP+ + 3 H2O; this corresponds to the MetaCyc reaction RXN-11262 (http://biocyc.org/META/NEW-IMAGE?type=REACTION&object=RXN-11262) and the KEGG reaction R08986 (http://www.genome.jp/dbget-bin/www_bget?rn:R08986).		mah	2011-01-12T01:54:31Z						molecular_function											owl:Class	
GO:0048565	biolink:NamedThing	digestive tract development	The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.	got7fsn_ti	intestinal development|intestine development|gut development													biological_process											owl:Class	
GO:0008013	biolink:NamedThing	beta-catenin binding	Binding to a catenin beta subunit.	got7fsn_ti														molecular_function											owl:Class	
GO:0018140	biolink:NamedThing	peptide cross-linking via L-cysteine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	got7fsn_ti												RESID:AA0244		biological_process											owl:Class	
GO:0008964	biolink:NamedThing	phosphoenolpyruvate carboxylase activity	Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.	got7fsn_ti	PEPC|phosphate:oxaloacetate carboxy-lyase (phosphorylating)|PEP carboxylase activity|phosphopyruvate (phosphate) carboxylase activity|phosphoenolpyruvic carboxylase activity|phosphate:oxaloacetate carboxy-lyase (adding phosphate; phosphoenolpyruvate-forming)|PEPCase activity											KEGG_REACTION:R00345|MetaCyc:PEPCARBOX-RXN|RHEA:28370|EC:4.1.1.31		molecular_function											owl:Class	
GO:0004611	biolink:NamedThing	phosphoenolpyruvate carboxykinase activity	Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products.	got7fsn_ti	PEPCK activity|PEP carboxykinase activity|phosphopyruvate carboxylase activity											EC:4.1.1.32		molecular_function											owl:Class	
GO:0061131	biolink:NamedThing	pancreas field specification	The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.	got7fsn_ti							dph	2010-05-17T09:39:49Z						biological_process											owl:Class	
GO:0010092	biolink:NamedThing	specification of animal organ identity	The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0015424	biolink:NamedThing	ABC-type amino acid transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).	got7fsn_ti	amino acid ABC transporter|ATPase-coupled amino acid transmembrane transporter activity|amino acid-importing ATPase activity|ATP-dependent amino acid transmembrane transporter activity|amino acid-transporting ATPase activity|amino acid-exporting ATPase activity										GO:0032518|GO:0032520			molecular_function											owl:Class	
GO:0002522	biolink:NamedThing	leukocyte migration involved in immune response	The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.	got7fsn_ti	leucocyte trafficking during immune response|immune cell migration during immune response|leukocyte trafficking during immune response|leucocyte migration during immune response|immune cell trafficking during immune response													biological_process											owl:Class	
GO:0016648	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide.	got7fsn_ti	oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor											EC:1.5.4.-		molecular_function											owl:Class	
GO:0060952	biolink:NamedThing	cardiac glial cell development	The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.	got7fsn_ti							dph	2009-09-29T03:09:24Z						biological_process											owl:Class	
GO:0021782	biolink:NamedThing	glial cell development	The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0051447	biolink:NamedThing	negative regulation of meiotic cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.	got7fsn_ti	down regulation of progression through meiotic cell cycle|inhibition of progression through meiotic cell cycle|negative regulation of meiotic cell cycle progression|negative regulation of progression through meiotic cell cycle|downregulation of progression through meiotic cell cycle|down-regulation of progression through meiotic cell cycle													biological_process											owl:Class	
GO:2000242	biolink:NamedThing	negative regulation of reproductive process	Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.	got7fsn_ti							mah	2010-11-10T02:44:05Z						biological_process											owl:Class	
GO:0061673	biolink:NamedThing	mitotic spindle astral microtubule	Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.	got7fsn_ti							dph	2014-12-08T18:27:20Z						cellular_component											owl:Class	
GO:0000235	biolink:NamedThing	astral microtubule	Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0045621	biolink:NamedThing	positive regulation of lymphocyte differentiation	Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.	got7fsn_ti	up-regulation of lymphocyte differentiation|positive regulation of lymphocyte development|activation of lymphocyte differentiation|stimulation of lymphocyte differentiation|upregulation of lymphocyte differentiation|up regulation of lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0051251	biolink:NamedThing	positive regulation of lymphocyte activation	Any process that activates or increases the frequency, rate or extent of lymphocyte activation.	got7fsn_ti	activation of lymphocyte activation|up-regulation of lymphocyte activation|upregulation of lymphocyte activation|up regulation of lymphocyte activation|stimulation of lymphocyte activation													biological_process											owl:Class	
GO:0001990	biolink:NamedThing	regulation of systemic arterial blood pressure by hormone	The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.	got7fsn_ti	hormonal control of blood pressure|blood pressure regulation by hormone|hormonal regulation of blood pressure													biological_process											owl:Class	
GO:0003044	biolink:NamedThing	regulation of systemic arterial blood pressure mediated by a chemical signal	The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.	got7fsn_ti	blood pressure regulation mediated by a chemical signal													biological_process											owl:Class	
GO:1903043	biolink:NamedThing	positive regulation of chondrocyte hypertrophy	Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy.	got7fsn_ti	up regulation of chondrocyte hypertrophy|upregulation of chondrocyte hypertrophy|activation of chondrocyte hypertrophy|up-regulation of chondrocyte hypertrophy						mr	2014-05-20T21:23:25Z						biological_process											owl:Class	
GO:2001106	biolink:NamedThing	regulation of Rho guanyl-nucleotide exchange factor activity	Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.	got7fsn_ti	regulation of RhoGEF|regulation of Rho guanine nucleotide exchange factor						yaf	2011-09-23T10:13:06Z						biological_process											owl:Class	
GO:1905097	biolink:NamedThing	regulation of guanyl-nucleotide exchange factor activity	Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity.	got7fsn_ti	regulation of GNRP|regulation of guanyl-nucleotide release factor activity|regulation of GDS|regulation of guanyl-nucleotide releasing factor|regulation of GDP-dissociation stimulator activity|regulation of GEF	https://github.com/geneontology/go-ontology/issues/18750					sl	2016-03-31T16:09:35Z						biological_process											owl:Class	
GO:0071429	biolink:NamedThing	snRNA-containing ribonucleoprotein complex export from nucleus	The directed movement of a ribonucleoprotein complex that contains small nuclear RNA from the nucleus to the cytoplasm.	got7fsn_ti	snRNA-containing ribonucleoprotein complex export from cell nucleus|snRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|snRNA-containing RNP export from nucleus|snRNA-containing ribonucleoprotein complex nucleus export						mah	2009-12-16T10:15:38Z						biological_process											owl:Class	
GO:0071426	biolink:NamedThing	ribonucleoprotein complex export from nucleus	The directed movement of a ribonucleoprotein complex from the nucleus to the cytoplasm.	got7fsn_ti	ribonucleoprotein complex export from cell nucleus|RNP export from nucleus|ribonucleoprotein complex nucleus export|ribonucleoprotein complex transport from nucleus to cytoplasm						mah	2009-12-16T10:13:01Z						biological_process											owl:Class	
GO:0010469	biolink:NamedThing	regulation of signaling receptor activity	Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.	got7fsn_ti	regulation of signalling receptor activity|regulation of receptor activity													biological_process											owl:Class	
GO:0044476	biolink:NamedThing	envenomation resulting in negative regulation of low voltage-gated calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:28:42Z						biological_process											owl:Class	
GO:0044474	biolink:NamedThing	envenomation resulting in negative regulation of voltage-gated calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:25:04Z						biological_process											owl:Class	
GO:0102563	biolink:NamedThing	aurachin C monooxygenase activity	Catalysis of the reaction: aurachin C + O2 + H+ + NAD(P)H <=> aurachin C epoxide + H2O + NAD(P).	got7fsn_ti												MetaCyc:RXN-15029		molecular_function											owl:Class	
GO:0048461	biolink:NamedThing	flower structural organization	The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	flower structural organisation										GO:0048412			biological_process											owl:Class	
GO:0061570	biolink:NamedThing	dCDP phosphorylation	The process of introducing a phosphate group into dCDP to produce a dCTP.	got7fsn_ti							dph	2013-08-01T13:02:16Z						biological_process											owl:Class	
GO:1990708	biolink:NamedThing	conditioned place preference	The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug.	got7fsn_ti							sl	2015-03-18T20:28:59Z						biological_process											owl:Class	
GO:0008306	biolink:NamedThing	associative learning	Learning by associating a stimulus (the cause) with a particular outcome (the effect).	got7fsn_ti	classical conditioning|conditional learning|Pavlovian conditioning|conditional response											Wikipedia:Learning#Associative_learning		biological_process											owl:Class	
GO:0044589	biolink:NamedThing	pectin binding	Binding to pectin.	got7fsn_ti							jl	2012-04-26T01:26:56Z						molecular_function											owl:Class	
GO:0048028	biolink:NamedThing	galacturonan binding	Binding to a simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins.	got7fsn_ti	polygalacturonide binding													molecular_function											owl:Class	
GO:0043970	biolink:NamedThing	histone H3-K9 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone.	got7fsn_ti	histone H3K9 acetylation|histone H3 acetylation at K9													biological_process											owl:Class	
GO:0043966	biolink:NamedThing	histone H3 acetylation	The modification of histone H3 by the addition of an acetyl group.	got7fsn_ti														biological_process											owl:Class	
GO:0036192	biolink:NamedThing	3-hydroxyindolin-2-one monooxygenase activity	Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.	got7fsn_ti	3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming)						bf	2012-04-19T11:45:33Z				RHEA:31927|KEGG_REACTION:R07422|EC:1.14.14.109		molecular_function											owl:Class	
GO:0016897	biolink:NamedThing	exoribonuclease activity, producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.	got7fsn_ti												EC:3.1.14.-		molecular_function											owl:Class	
GO:0004532	biolink:NamedThing	exoribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule.	got7fsn_ti												Reactome:R-HSA-429961		molecular_function											owl:Class	
GO:0036225	biolink:NamedThing	cellular response to vitamin B1 starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine).	got7fsn_ti	cellular response to thiamin starvation|cellular response to vitamin B1 deprivation						bf	2012-05-09T02:35:55Z						biological_process											owl:Class	
GO:0007500	biolink:NamedThing	mesodermal cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	mesoderm cell fate determination				Note that this term was 'mesoderm determination'. Changed string to make more consistent with parent term 'cell fate determination'.									biological_process											owl:Class	
GO:0035896	biolink:NamedThing	positive regulation of mast cell degranulation in other organism	Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism.	got7fsn_ti	up-regulation of mast cell degranulation in other organism|upregulation of mast cell degranulation in other organism						bf	2011-06-15T02:49:03Z						biological_process											owl:Class	
GO:0035895	biolink:NamedThing	modulation of mast cell degranulation in other organism	Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.	got7fsn_ti	regulation of mast cell degranulation in other organism						bf	2011-06-15T02:46:50Z						biological_process											owl:Class	
GO:0009668	biolink:NamedThing	plastid membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid.	got7fsn_ti	plastid membrane organization and biogenesis|plastid membrane organisation													biological_process											owl:Class	
GO:0032395	biolink:NamedThing	MHC class II receptor activity	Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	T cell receptor activity|gamma-delta T cell receptor activity|alpha-beta T cell receptor activity				Note that this term is intended for annotation of gene products that act as receptors for MHC class II protein complexes, not for components of the MHC class II protein complexes themselves.									molecular_function											owl:Class	
GO:0035165	biolink:NamedThing	embryonic crystal cell differentiation	The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.	got7fsn_ti														biological_process											owl:Class	
GO:0021630	biolink:NamedThing	olfactory nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	got7fsn_ti	CN I maturation													biological_process											owl:Class	
GO:0071003	biolink:NamedThing	penta-snRNP complex	A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.	got7fsn_ti	penta-RNP complex						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0097525	biolink:NamedThing	spliceosomal snRNP complex	A small ribonucleoprotein complex involved in formation of the spliceosome.	got7fsn_ti							pr	2013-10-18T15:57:45Z						cellular_component											owl:Class	
GO:0003341	biolink:NamedThing	cilium movement	The directed, self-propelled movement of a cilium.	got7fsn_ti	flagellar motility|cilium beating|ciliary motility|flagellar movement|microtubule-based flagellum movement|flagellum movement				Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-11-24T09:56:26Z			GO:0036142			biological_process											owl:Class	
GO:0010584	biolink:NamedThing	pollen exine formation	The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.	got7fsn_ti														biological_process											owl:Class	
GO:0010208	biolink:NamedThing	pollen wall assembly	The formation of reticulate pollen wall pattern consisting of two layers, exine and intine.	got7fsn_ti	pollen wall formation													biological_process											owl:Class	
GO:0015986	biolink:NamedThing	ATP synthesis coupled proton transport	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.	got7fsn_ti	chemiosmosis													biological_process											owl:Class	
GO:0006754	biolink:NamedThing	ATP biosynthetic process	The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	got7fsn_ti	ATP formation|ATP biosynthesis|ATP regeneration|ATP synthesis|ATP anabolism										GO:0006758|GO:0006759			biological_process											owl:Class	
GO:0110156	biolink:NamedThing	methylguanosine-cap decapping	Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.	got7fsn_ti							kmv	2019-07-08T17:31:07Z						biological_process											owl:Class	
GO:0009080	biolink:NamedThing	pyruvate family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine.	got7fsn_ti	pyruvate family amino acid degradation|pyruvate family amino acid breakdown|pyruvate family amino acid catabolism													biological_process											owl:Class	
GO:0009078	biolink:NamedThing	pyruvate family amino acid metabolic process	The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine.	got7fsn_ti	pyruvate family amino acid metabolism													biological_process											owl:Class	
GO:0050865	biolink:NamedThing	regulation of cell activation	Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	got7fsn_ti														biological_process											owl:Class	
GO:0051059	biolink:NamedThing	NF-kappaB binding	Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.	got7fsn_ti														molecular_function											owl:Class	
GO:0061629	biolink:NamedThing	RNA polymerase II-specific DNA-binding transcription factor binding	Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.	got7fsn_ti	RNA polymerase II transcription factor binding|RNA polymerase II sequence-specific DNA binding transcription factor binding|RNA polymerase II activating transcription factor binding|RNA polymerase II repressing transcription factor binding|RNA polymerase II sequence-specific DNA-binding transcription factor binding	https://github.com/geneontology/go-ontology/issues/19354					dph	2014-05-15T09:12:24Z			GO:0001103|GO:0001085|GO:0001102			molecular_function											owl:Class	
GO:0071187	biolink:NamedThing	protocadherin-alpha-v4-protocadherin-gamma-b4 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti	Pcdhga1-Pcdhgb4 complex						mah	2009-11-23T04:22:08Z						cellular_component											owl:Class	
GO:0098543	biolink:NamedThing	detection of other organism	The series of events in which a stimulus from another organism is received and converted into a molecular signal.	got7fsn_ti	recognition of other organism involved in symbiotic interaction|recognition of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/17977					dos	2013-11-11T14:28:54Z			GO:0051824			biological_process											owl:Class	
GO:0010412	biolink:NamedThing	mannan metabolic process	The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units.	got7fsn_ti	mannan metabolism													biological_process											owl:Class	
GO:0050118	biolink:NamedThing	N-acetyldiaminopimelate deacetylase activity	Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + acetate.	got7fsn_ti	N-acetyl-L-diaminopimelic acid deacylase activity|N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-acetyl-LL-diaminopimelate deacylase activity|6-N-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity											RHEA:20405|MetaCyc:N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN|KEGG_REACTION:R02733|EC:3.5.1.47		molecular_function											owl:Class	
GO:1990255	biolink:NamedThing	subsynaptic reticulum organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.	got7fsn_ti							tb	2013-12-13T23:05:21Z						biological_process											owl:Class	
GO:0006996	biolink:NamedThing	organelle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.	got7fsn_ti	organelle organization and biogenesis|single-organism organelle organization|single organism organelle organization|organelle organisation						jl	2013-12-19T15:25:51Z			GO:1902589			biological_process											owl:Class	
GO:0016993	biolink:NamedThing	precorrin-8X methylmutase activity	Catalysis of the reaction: precorrin-8X = hydrogenobyrinate.	got7fsn_ti	HBA synthase activity|hydrogenobyrinic acid-binding protein activity|precorrin isomerase activity|precorrin-8X 11,12-methylmutase activity											RHEA:22512|MetaCyc:5.4.1.2-RXN|EC:5.4.99.61		molecular_function											owl:Class	
GO:0016867	biolink:NamedThing	intramolecular transferase activity, transferring acyl groups	Catalysis of the transfer of an acyl group from one position to another within a single molecule.	got7fsn_ti												EC:5.4.1.-		molecular_function											owl:Class	
GO:0034867	biolink:NamedThing	2,4,4-trimethylpent-2-enoyl-CoA hydratase activity	Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r1277		molecular_function											owl:Class	
GO:0004711	biolink:NamedThing	ribosomal protein S6 kinase activity	Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.	got7fsn_ti														molecular_function											owl:Class	
GO:0004674	biolink:NamedThing	protein serine/threonine kinase activity	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	got7fsn_ti	protein threonine kinase activity|serine/threonine protein kinase activity|protein serine kinase activity|threonine-specific protein kinase activity|protein-serine kinase activity|protein phosphokinase activity|protein kinase (phosphorylating) activity|serine kinase activity|protein serine-threonine kinase activity|serine(threonine) protein kinase activity|serine-specific protein kinase activity|serine protein kinase activity	https://github.com/geneontology/go-ontology/issues/20114									GO:0106311|GO:0004696|GO:0004695|GO:0004700	Reactome:R-HSA-75809|Reactome:R-HSA-5679205|Reactome:R-HSA-111919|Reactome:R-HSA-442832|Reactome:R-HSA-2029460|Reactome:R-HSA-193705|Reactome:R-HSA-5682101|Reactome:R-HSA-450474|Reactome:R-HSA-165726|Reactome:R-HSA-199298|Reactome:R-HSA-5672828|Reactome:R-HSA-5624492|Reactome:R-HSA-936951|Reactome:R-HSA-6799409|Reactome:R-HSA-2399977|Reactome:R-HSA-111970|Reactome:R-HSA-8873929|Reactome:R-HSA-450325|Reactome:R-HSA-2028673|Reactome:R-HSA-6798372|Reactome:R-HSA-201691|Reactome:R-HSA-5687183|RHEA:46608|Reactome:R-HSA-3229102|Reactome:R-HSA-9653503|Reactome:R-HSA-2028635|Reactome:R-HSA-9648089|Reactome:R-HSA-5687086|Reactome:R-HSA-195318|Reactome:R-HSA-5683801|Reactome:R-HSA-1445144|Reactome:R-HSA-3239014|Reactome:R-HSA-5668545|Reactome:R-HSA-8868666|Reactome:R-HSA-1225894|Reactome:R-HSA-8878050|Reactome:R-HSA-188350|Reactome:R-HSA-5672948|Reactome:R-HSA-5668984|Reactome:R-HSA-9619515|Reactome:R-HSA-428961|Reactome:R-HSA-3928608|Reactome:R-HSA-8868340|Reactome:R-HSA-5218821|Reactome:R-HSA-6795460|Reactome:R-HSA-5671763|Reactome:R-HSA-166245|Reactome:R-HSA-9619843|Reactome:R-HSA-1362270|Reactome:R-HSA-2399941|Reactome:R-HSA-448955|Reactome:R-HSA-5607722|Reactome:R-HSA-450222|Reactome:R-HSA-975861|Reactome:R-HSA-9610156|Reactome:R-HSA-975865|Reactome:R-HSA-1168635|Reactome:R-HSA-6805399|Reactome:R-HSA-937022|Reactome:R-HSA-399950|Reactome:R-HSA-5684887|Reactome:R-HSA-1181355|Reactome:R-HSA-170977|Reactome:R-HSA-5669250|Reactome:R-HSA-163416|Reactome:R-HSA-975125|Reactome:R-HSA-5685230|Reactome:R-HSA-5683964|Reactome:R-HSA-5213464|Reactome:R-HSA-450463|Reactome:R-HSA-198599|Reactome:R-HSA-8853444|Reactome:R-HSA-380272|Reactome:R-HSA-9645535|Reactome:R-HSA-9656214|Reactome:R-HSA-1549526|Reactome:R-HSA-6814409|Reactome:R-HSA-5674496|Reactome:R-HSA-5357831|Reactome:R-HSA-9612501|Reactome:R-HSA-1181149|Reactome:R-HSA-2730876|Reactome:R-HSA-2028583|Reactome:R-HSA-6795290|Reactome:R-HSA-6802973|Reactome:R-HSA-5632670|Reactome:R-HSA-374696|Reactome:R-HSA-400382|Reactome:R-HSA-199935|Reactome:R-HSA-176116|Reactome:R-HSA-3228469|Reactome:R-HSA-75028|Reactome:R-HSA-392752|Reactome:R-HSA-5682598|Reactome:R-HSA-9634702|Reactome:R-HSA-349444|Reactome:R-HSA-2399981|Reactome:R-HSA-139918|Reactome:R-HSA-913996|Reactome:R-HSA-975180|Reactome:R-HSA-6802919|Reactome:R-HSA-5693598|Reactome:R-HSA-8878054|Reactome:R-HSA-2294580|Reactome:R-HSA-5687094|Reactome:R-HSA-5675198|Reactome:R-HSA-3858480|Reactome:R-HSA-5213466|Reactome:R-HSA-2028589|Reactome:R-HSA-9613530|Reactome:R-HSA-187688|Reactome:R-HSA-9008822|Reactome:R-HSA-975170|Reactome:R-HSA-377186|Reactome:R-HSA-4551570|Reactome:R-HSA-211164|Reactome:R-HSA-2060328|Reactome:R-HSA-198371|Reactome:R-HSA-2028598|Reactome:R-HSA-8939963|Reactome:R-HSA-5692768|Reactome:R-HSA-2984226|Reactome:R-HSA-934559|Reactome:R-HSA-8868260|Reactome:R-HSA-199910|Reactome:R-HSA-3371531|Reactome:R-HSA-9012319|Reactome:R-HSA-6805126|Reactome:R-HSA-9023132|Reactome:R-HSA-446694|Reactome:R-HSA-8948039|Reactome:R-HSA-8944454|Reactome:R-HSA-3209160|Reactome:R-HSA-2422927|Reactome:R-HSA-6805640|Reactome:R-HSA-9694293|Reactome:R-HSA-170055|Reactome:R-HSA-1168641|Reactome:R-HSA-156723|Reactome:R-HSA-69685|Reactome:R-HSA-3928640|Reactome:R-HSA-448948|Reactome:R-HSA-389756|Reactome:R-HSA-8940100|Reactome:R-HSA-9612509|Reactome:R-HSA-3857329|Reactome:R-HSA-163010|Reactome:R-HSA-5687121|Reactome:R-HSA-5357472|Reactome:R-HSA-5627775|Reactome:R-HSA-5682983|Reactome:R-HSA-6800490|Reactome:R-HSA-5682026|Reactome:R-HSA-975874|Reactome:R-HSA-156699|Reactome:R-HSA-211583|Reactome:R-HSA-975160|Reactome:R-HSA-5610718|Reactome:R-HSA-2730896|Reactome:R-HSA-5218854|Reactome:R-HSA-2399966|Reactome:R-HSA-5635842|Reactome:R-HSA-2168079|Reactome:R-HSA-8877691|Reactome:R-HSA-9032751|Reactome:R-HSA-198609|Reactome:R-HSA-381091|Reactome:R-HSA-164151|Reactome:R-HSA-429016|Reactome:R-HSA-5668947|Reactome:R-HSA-5672978|Reactome:R-HSA-6802933|Reactome:R-HSA-8948146|Reactome:R-HSA-5668932|Reactome:R-HSA-8952289|Reactome:R-HSA-9032863|Reactome:R-HSA-975134|Reactome:R-HSA-202510|Reactome:R-HSA-166284|Reactome:R-HSA-5218826|Reactome:R-HSA-3000327|Reactome:R-HSA-3249371|Reactome:R-HSA-5685242|Reactome:R-HSA-2399996|Reactome:R-HSA-5672973|Reactome:R-HSA-5229343|Reactome:R-HSA-2243938|Reactome:R-HSA-9620004|Reactome:R-HSA-109823|Reactome:R-HSA-9612980|Reactome:R-HSA-5260201|Reactome:R-HSA-156678|Reactome:R-HSA-2730868|Reactome:R-HSA-6805276|Reactome:R-HSA-198270|Reactome:R-HSA-168140|Reactome:R-HSA-165758|Reactome:R-HSA-8852306|Reactome:R-HSA-209087|Reactome:R-HSA-5607732|Reactome:R-HSA-2028591|Reactome:R-HSA-9610153|Reactome:R-HSA-176298|Reactome:R-HSA-9627089|Reactome:R-HSA-5693551|Reactome:R-HSA-109862|Reactome:R-HSA-4332388|Reactome:R-HSA-3928616|Reactome:R-HSA-112342|Reactome:R-HSA-170076|Reactome:R-HSA-5607742|Reactome:R-HSA-3928625|Reactome:R-HSA-156673|Reactome:R-HSA-9610163|Reactome:R-HSA-2574840|Reactome:R-HSA-1592233|Reactome:R-HSA-912470|Reactome:R-HSA-9009208|Reactome:R-HSA-381111|Reactome:R-HSA-349455|Reactome:R-HSA-6804276|Reactome:R-HSA-6811454|Reactome:R-HSA-5218814|Reactome:R-HSA-5686704|Reactome:R-HSA-112381|Reactome:R-HSA-3769394|Reactome:R-HSA-9626880|Reactome:R-HSA-3222020|Reactome:R-HSA-2029454|Reactome:R-HSA-199917|Reactome:R-HSA-198611|Reactome:R-HSA-2399992|Reactome:R-HSA-4411383|Reactome:R-HSA-8863895|Reactome:R-HSA-109822|Reactome:R-HSA-200421|Reactome:R-HSA-2470508|Reactome:R-HSA-9632868|Reactome:R-HSA-109860|Reactome:R-HSA-2430535|Reactome:R-HSA-156682|Reactome:R-HSA-3132737|Reactome:R-HSA-2399985|Reactome:R-HSA-5218906|Reactome:R-HSA-6788392|Reactome:R-HSA-199839|Reactome:R-HSA-9656215|Reactome:R-HSA-6802935|Reactome:R-HSA-2993898|Reactome:R-HSA-9648883|Reactome:R-HSA-201677|Reactome:R-HSA-198746|Reactome:R-HSA-6805479|Reactome:R-HSA-198731|Reactome:R-HSA-9648888|Reactome:R-HSA-5693549|Reactome:R-HSA-1449597|Reactome:R-HSA-8850945|Reactome:R-HSA-139908|Reactome:R-HSA-9013978|Reactome:R-HSA-165182|Reactome:R-HSA-8863007|Reactome:R-HSA-5687101|Reactome:R-HSA-8868573|Reactome:R-HSA-1458463|Reactome:R-HSA-2029469|Reactome:R-HSA-399952|Reactome:R-HSA-2984258|Reactome:R-HSA-8948757|Reactome:R-HSA-195275|RHEA:17989|Reactome:R-HSA-6802911|Reactome:R-HSA-8863014|Reactome:R-HSA-187949|Reactome:R-HSA-9008480|Reactome:R-HSA-166286|Reactome:R-HSA-975853|Reactome:R-HSA-2562526|Reactome:R-HSA-2396007|Reactome:R-HSA-5675194|Reactome:R-HSA-9662823|Reactome:R-HSA-349426|Reactome:R-HSA-5684140|Reactome:R-HSA-8868344|Reactome:R-HSA-1181156|Reactome:R-HSA-6805785|Reactome:R-HSA-5671919|Reactome:R-HSA-199895|Reactome:R-HSA-3239019|Reactome:R-HSA-442739|Reactome:R-HSA-6798374|Reactome:R-HSA-5693536|Reactome:R-HSA-5610730|Reactome:R-HSA-195287|Reactome:R-HSA-399944|Reactome:R-HSA-202541|Reactome:R-HSA-201717|Reactome:R-HSA-5693575|Reactome:R-HSA-5693609|Reactome:R-HSA-6801666|Reactome:R-HSA-3928577|Reactome:R-HSA-5683792|EC:2.7.11.1|Reactome:R-HSA-2399999|Reactome:R-HSA-446701|Reactome:R-HSA-165766|Reactome:R-HSA-3371567|Reactome:R-HSA-2028679|Reactome:R-HSA-3857328|Reactome:R-HSA-9683664|Reactome:R-HSA-5675868|Reactome:R-HSA-9681627|Reactome:R-HSA-9652165|Reactome:R-HSA-450827|Reactome:R-HSA-3000310|Reactome:R-HSA-6805059|Reactome:R-HSA-8868567|Reactome:R-HSA-202222|Reactome:R-HSA-6804955|Reactome:R-HSA-174119|Reactome:R-HSA-5665868|Reactome:R-HSA-937059|Reactome:R-HSA-9633008|Reactome:R-HSA-2028555|Reactome:R-HSA-5683425|Reactome:R-HSA-5692775|Reactome:R-HSA-8853419|Reactome:R-HSA-419087|Reactome:R-HSA-2028675|Reactome:R-HSA-2990880|Reactome:R-HSA-2028661|Reactome:R-HSA-5607726|Reactome:R-HSA-2730856|Reactome:R-HSA-5357477|Reactome:R-HSA-3371435|Reactome:R-HSA-5632672|Reactome:R-HSA-2529020|Reactome:R-HSA-445072|Reactome:R-HSA-198756|Reactome:R-HSA-5635841|Reactome:R-HSA-5610732|Reactome:R-HSA-199929|Reactome:R-HSA-166119|Reactome:R-HSA-174174|Reactome:R-HSA-8870558|Reactome:R-HSA-77071|Reactome:R-HSA-6799097|Reactome:R-HSA-399978|Reactome:R-HSA-167098|Reactome:R-HSA-450490|Reactome:R-HSA-1632857|Reactome:R-HSA-9694620|Reactome:R-HSA-165718|Reactome:R-HSA-8868118|Reactome:R-HSA-4332358|Reactome:R-HSA-165777|Reactome:R-HSA-419197|Reactome:R-HSA-9673346|Reactome:R-HSA-4088134|Reactome:R-HSA-69891|Reactome:R-HSA-1638803|Reactome:R-HSA-199863|Reactome:R-HSA-193647|Reactome:R-HSA-5082405|Reactome:R-HSA-975878|Reactome:R-HSA-165692|Reactome:R-HSA-165162|Reactome:R-HSA-442724|Reactome:R-HSA-9007539|Reactome:R-HSA-399951|Reactome:R-HSA-399939|Reactome:R-HSA-198621|Reactome:R-HSA-8876446|Reactome:R-HSA-5578777|Reactome:R-HSA-5666160|Reactome:R-HSA-2466068|Reactome:R-HSA-6795473|Reactome:R-HSA-3928620|Reactome:R-HSA-9604328|Reactome:R-HSA-2400001|Reactome:R-HSA-5228811|Reactome:R-HSA-1168638|Reactome:R-HSA-5693540|Reactome:R-HSA-2399988|Reactome:R-HSA-2028629|Reactome:R-HSA-5672010|Reactome:R-HSA-5672008|Reactome:R-HSA-1454699|Reactome:R-HSA-2243942|Reactome:R-HSA-5610722|Reactome:R-HSA-162657|Reactome:R-HSA-419083|Reactome:R-HSA-69604|Reactome:R-HSA-162363|Reactome:R-HSA-170116|Reactome:R-HSA-4332363|Reactome:R-HSA-6805103|Reactome:R-HSA-429714|Reactome:R-HSA-5690250|Reactome:R-HSA-211650|Reactome:R-HSA-933525|Reactome:R-HSA-2730900|Reactome:R-HSA-5685156|Reactome:R-HSA-451152|Reactome:R-HSA-198347|Reactome:R-HSA-450499|Reactome:R-HSA-198640|Reactome:R-HSA-6801675|Reactome:R-HSA-5686578|Reactome:R-HSA-3222006|Reactome:R-HSA-8852317|Reactome:R-HSA-167084|Reactome:R-HSA-6799246|Reactome:R-HSA-8863011|Reactome:R-HSA-5687090|Reactome:R-HSA-918229|Reactome:R-HSA-6810233|Reactome:R-HSA-170087|Reactome:R-HSA-200143|Reactome:R-HSA-6799332|Reactome:R-HSA-198669|Reactome:R-HSA-109702|Reactome:R-HSA-451347|Reactome:R-HSA-75820|Reactome:R-HSA-2399982|Reactome:R-HSA-163418|Reactome:R-HSA-9022314|Reactome:R-HSA-69608|Reactome:R-HSA-6802943|Reactome:R-HSA-75010|Reactome:R-HSA-8933446|Reactome:R-HSA-5218916|Reactome:R-HSA-2028284|Reactome:R-HSA-5694441|Reactome:R-HSA-1358791|Reactome:R-HSA-6802926|Reactome:R-HSA-5624473|Reactome:R-HSA-202459|Reactome:R-HSA-202500|Reactome:R-HSA-419644|Reactome:R-HSA-2176475|Reactome:R-HSA-6804266|Reactome:R-HSA-2399969|Reactome:R-HSA-5684096|Reactome:R-HSA-195300|Reactome:R-HSA-202437|Reactome:R-HSA-199299|Reactome:R-HSA-5692779|Reactome:R-HSA-170126|Reactome:R-HSA-4411402|Reactome:R-HSA-8942836|Reactome:R-HSA-3772435|Reactome:R-HSA-195283|Reactome:R-HSA-3229152|Reactome:R-HSA-8856813|Reactome:R-HSA-8854908|Reactome:R-HSA-198613|Reactome:R-HSA-432110|Reactome:R-HSA-168053|Reactome:R-HSA-4793911|Reactome:R-HSA-9624526|Reactome:R-HSA-9699579|Reactome:R-HSA-5082387|Reactome:R-HSA-2214351|Reactome:R-HSA-2028670|Reactome:R-HSA-9633742|Reactome:R-HSA-6805285|Reactome:R-HSA-4608825		molecular_function											owl:Class	
GO:0004131	biolink:NamedThing	cytosine deaminase activity	Catalysis of the reaction: cytosine + H2O = uracil + NH3.	got7fsn_ti	cytosine aminohydrolase activity|isocytosine deaminase activity											RHEA:20605|MetaCyc:CYTDEAM-RXN|EC:3.5.4.1		molecular_function											owl:Class	
GO:0044490	biolink:NamedThing	positive regulation of voltage-gated sodium channel activity in other organism	Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.	got7fsn_ti							jl	2012-02-01T12:21:26Z						biological_process											owl:Class	
GO:0044488	biolink:NamedThing	modulation of voltage-gated sodium channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.	got7fsn_ti							jl	2012-02-01T11:48:25Z						biological_process											owl:Class	
GO:0007279	biolink:NamedThing	pole cell formation	Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells.	got7fsn_ti					See also the Cell Ontology term 'pole cell ; CL:0000301'.									biological_process											owl:Class	
GO:0048703	biolink:NamedThing	embryonic viscerocranium morphogenesis	The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.	got7fsn_ti	embryonic pharyngeal skeleton morphogenesis													biological_process											owl:Class	
GO:0042631	biolink:NamedThing	cellular response to water deprivation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.	got7fsn_ti	cellular response to drought													biological_process											owl:Class	
GO:0071462	biolink:NamedThing	cellular response to water stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.	got7fsn_ti							mah	2009-12-18T11:32:44Z						biological_process											owl:Class	
GO:0001754	biolink:NamedThing	eye photoreceptor cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.	got7fsn_ti														biological_process											owl:Class	
GO:0048232	biolink:NamedThing	male gamete generation	Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.	got7fsn_ti														biological_process											owl:Class	
GO:0007276	biolink:NamedThing	gamete generation	The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.	got7fsn_ti	gametogenesis										GO:0009552			biological_process											owl:Class	
GO:0050767	biolink:NamedThing	regulation of neurogenesis	Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0044829	biolink:NamedThing	positive regulation by host of viral genome replication	A process in which a host organism activates or increases the frequency, rate or extent of  viral genome replication.	got7fsn_ti							jl	2014-02-06T11:35:07Z						biological_process											owl:Class	
GO:0044827	biolink:NamedThing	modulation by host of viral genome replication	A process in which a host organism modulates the frequency, rate or extent of viral genome replication.	got7fsn_ti	regulation by host of viral genome reproduction						jl	2014-02-06T11:26:45Z						biological_process											owl:Class	
GO:0015951	biolink:NamedThing	purine ribonucleotide interconversion	The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.	got7fsn_ti														biological_process											owl:Class	
GO:0015950	biolink:NamedThing	purine nucleotide interconversion	The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide.	got7fsn_ti														biological_process											owl:Class	
GO:0009644	biolink:NamedThing	response to high light intensity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0009642	biolink:NamedThing	response to light intensity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0039629	biolink:NamedThing	T=219 icosahedral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=219 symmetry. T=219 icosahedral capsid is composed of 12 pentameric and 2180 hexameric capsomeres for a total of 13140 capsid proteins.	got7fsn_ti							bf	2012-08-03T16:29:00Z						cellular_component											owl:Class	
GO:0019030	biolink:NamedThing	icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure.	got7fsn_ti	quasispherical viral capsid													cellular_component											owl:Class	
GO:0071986	biolink:NamedThing	Ragulator complex	A vacuolar membrane-anchored guanine nucleotide exchange factor (GEF) complex for the Rag GTPases (Gtr1-Gtr2 GTPase complex GO:1990131) in TORC1 signalling pathway. In human, Ragulator is comprised of the membrane anchor subunit LAMTOR1 (Meh1p in S. cerevisiae, Lam1 in S. pombe), a GEF subunit LAMTOR2 ( Slm4 in S. cerevisiae , Lam2 in S. pombe ) , LAMTOR3 (no S. cerevisiae ortholog identified, Lam3 in S. pombe) , LAMTOR4 (no S. cerevisiae ortholog identified, Lam4 in S. pombe), and LAMTOR5 (no S. cerevisiae or S. pombe ortholog identified).	got7fsn_ti	GTPase-containing complex for Gap1p sorting in the endosome|MAPKSP1/ROBLD3/C11orf59 complex|EGO complex|EGO-GSE complex|GSE complex|Rag GEF	https://github.com/geneontology/go-ontology/issues/20822|https://github.com/geneontology/go-ontology/issues/21777					mah	2010-10-22T02:42:13Z			GO:0034449|GO:0034448			cellular_component											owl:Class	
GO:0032045	biolink:NamedThing	guanyl-nucleotide exchange factor complex	A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.	got7fsn_ti														cellular_component											owl:Class	
GO:0044850	biolink:NamedThing	menstrual cycle	A type of ovulation cycle where the endometrium is shed if pregnancy does not occur.	got7fsn_ti							jl	2014-07-16T13:51:29Z				Wikipedia:Menstrual_cycle		biological_process											owl:Class	
GO:0035592	biolink:NamedThing	establishment of protein localization to extracellular region	The directed movement of a protein to a specific location within the extracellular region.	got7fsn_ti	establishment of protein localization in extracellular region|establishment of protein localisation in extracellular region						bf	2010-11-09T10:25:08Z						biological_process											owl:Class	
GO:0033422	biolink:NamedThing	CCC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CCC codon.	got7fsn_ti	proline tRNA				Note that in the standard genetic code, CCC codes for proline.									molecular_function											owl:Class	
GO:0031174	biolink:NamedThing	lifelong otolith mineralization	The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added.	got7fsn_ti														biological_process											owl:Class	
GO:0036521	biolink:NamedThing	modulation by symbiont of host protein localization to phagocytic vesicle	Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host protein localisation to phagosome						bf	2016-06-06T14:47:10Z						biological_process											owl:Class	
GO:0044068	biolink:NamedThing	modulation by symbiont of host cellular process	Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism.	got7fsn_ti	regulation by symbiont of host cellular process|regulation of host cellular process by symbiont|modulation of host cellular process by symbiont													biological_process											owl:Class	
GO:0034523	biolink:NamedThing	3-formylsalicylate oxidase activity	Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide.	got7fsn_ti												UM-BBD_reactionID:r0777		molecular_function											owl:Class	
GO:0043614	biolink:NamedThing	multi-eIF complex	A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5.	got7fsn_ti	multifactor translation initiation factor (eIF) complex													cellular_component											owl:Class	
GO:0072156	biolink:NamedThing	distal tubule morphogenesis	The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.	got7fsn_ti							mah	2010-02-24T02:32:03Z						biological_process											owl:Class	
GO:0072078	biolink:NamedThing	nephron tubule morphogenesis	The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.	got7fsn_ti							mah	2010-02-01T02:25:14Z						biological_process											owl:Class	
GO:0090709	biolink:NamedThing	regulation of timing of plant organ formation	Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development.	got7fsn_ti							tb	2016-10-05T12:49:58Z						biological_process											owl:Class	
GO:1905428	biolink:NamedThing	regulation of plant organ formation	Any process that modulates the frequency, rate or extent of plant organ formation.	got7fsn_ti							tb	2016-09-07T18:57:47Z						biological_process											owl:Class	
GO:0051358	biolink:NamedThing	peptide cross-linking via 2-imino-glutamic acid 5-imidazolinone glycine	The formation of the non-fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamic acid, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like non-fluorescent red chromoprotein from the sea anemone Radianthus macrodactylus.	got7fsn_ti	biosynthesis of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine				See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.							RESID:AA0378		biological_process											owl:Class	
GO:0019756	biolink:NamedThing	cyanogenic glycoside biosynthetic process	The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.	got7fsn_ti	cyanogenic glycoside synthesis|cyanogenic glycoside anabolism|cyanogenic glycoside formation|cyanogenic glycoside biosynthesis													biological_process											owl:Class	
GO:0008110	biolink:NamedThing	L-histidine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate.	got7fsn_ti	histidine-2-oxoglutarate aminotransferase activity|histidine aminotransferase activity|histidine transaminase activity											KEGG_REACTION:R01161|RHEA:16565|MetaCyc:HISTTRANSAM-RXN|EC:2.6.1.38		molecular_function											owl:Class	
GO:0000133	biolink:NamedThing	polarisome	Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p.	got7fsn_ti														cellular_component											owl:Class	
GO:0019125	biolink:NamedThing	peptidyl-phenylalanine racemization	The racemization of peptidyl-phenylalanine.	got7fsn_ti											GO:0018089|GO:0018371	RESID:AA0194		biological_process											owl:Class	
GO:0035838	biolink:NamedThing	growing cell tip	The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs.	got7fsn_ti	growing cell end						bf	2011-05-06T01:28:44Z						cellular_component											owl:Class	
GO:0030427	biolink:NamedThing	site of polarized growth	Any part of a cell where non-isotropic growth takes place.	got7fsn_ti											GO:0030483|GO:0000134			cellular_component											owl:Class	
GO:0102744	biolink:NamedThing	all-trans-geranyl-geranyl diphosphate reductase activity	Catalysis of the reaction: H+ + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + NADPH = dihydrogeranylgeranyl-PP + NADP.	got7fsn_ti												MetaCyc:RXN-7658		molecular_function											owl:Class	
GO:0031982	biolink:NamedThing	vesicle	Any small, fluid-filled, spherical organelle enclosed by membrane.	got7fsn_ti	membrane-enclosed vesicle|membrane-bounded vesicle										GO:0031988	Wikipedia:Vesicle_(biology)|NIF_Subcellular:sao221389602		cellular_component											owl:Class	
GO:0043227	biolink:NamedThing	membrane-bounded organelle	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.	got7fsn_ti	membrane-enclosed organelle											NIF_Subcellular:sao414196390		cellular_component											owl:Class	
GO:0102811	biolink:NamedThing	geraniol 10-hydroxylase activity	Catalysis of the reaction: geraniol + O2 + NADPH + H+ <=> (6E)-8-hydroxygeraniol + NADP + H2O.	got7fsn_ti												RHEA:32495|MetaCyc:RXN-8197|EC:1.14.14.83		molecular_function											owl:Class	
GO:0018589	biolink:NamedThing	di-n-butyltin dioxygenase activity	Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin.	got7fsn_ti	DBT dioxygenase activity											UM-BBD_reactionID:r0645		molecular_function											owl:Class	
GO:0007036	biolink:NamedThing	vacuolar calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.	got7fsn_ti														biological_process											owl:Class	
GO:1990096	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to superoxide	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.	got7fsn_ti							pr	2013-05-07T12:25:34Z						biological_process											owl:Class	
GO:1990095	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	got7fsn_ti							pr	2013-05-07T12:10:32Z						biological_process											owl:Class	
GO:0034421	biolink:NamedThing	post-translational protein acetylation	The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome.	got7fsn_ti	posttranslational protein amino acid acetylation|post-translational protein amino acid acetylation													biological_process											owl:Class	
GO:0002541	biolink:NamedThing	activation of plasma proteins involved in acute inflammatory response	Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.	got7fsn_ti														biological_process											owl:Class	
GO:0016051	biolink:NamedThing	carbohydrate biosynthetic process	The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.	got7fsn_ti	carbohydrate formation|carbohydrate biosynthesis|carbohydrate anabolism|anabolic carbohydrate metabolic process|anabolic carbohydrate metabolism|carbohydrate synthesis										GO:0006093			biological_process											owl:Class	
GO:0033164	biolink:NamedThing	glycolipid 1,6-alpha-mannosyltransferase activity	Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.	got7fsn_ti	GDP-mannose:glycolipid 1,6-alpha-D-mannosyltransferase activity|GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase activity|glycolipid 6-alpha-mannosyltransferase activity|initiation-specific alpha-1,6-mannosyltransferase activity|GDP-mannose:oligosaccharide 6-alpha-D-mannosyltransferase activity											EC:2.4.1.232|MetaCyc:2.4.1.232-RXN		molecular_function											owl:Class	
GO:0004376	biolink:NamedThing	glycolipid mannosyltransferase activity	Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.	got7fsn_ti	glycolipid mannosyl transferase activity										GO:0004580	Reactome:R-HSA-162873|Reactome:R-HSA-162821		molecular_function											owl:Class	
GO:0070463	biolink:NamedThing	tubulin-dependent ATPase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate.	got7fsn_ti	tubulin-activated ATPase activity													molecular_function											owl:Class	
GO:0140657	biolink:NamedThing	ATP-dependent activity	A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.	got7fsn_ti	ATPase activity, coupled|ATPase-dependent activity|ATP hydrolysis-dependent activity	https://github.com/geneontology/go-ontology/issues/21612			Note that this term represents a grouping class that includes all proteins that use ATP hydrolysis to drive a reaction; it is not meant to capture the ATP hydrolysis reaction itself. To annotate ATP hydrolysis, please use 'ATP hydrolysis activity ; GO:0016887'.		pg	2021-06-15T07:35:06Z						molecular_function											owl:Class	
GO:0061785	biolink:NamedThing	peptidoglycan endopeptidase activity	An endopeptidase activity that uses peptidoglycan as a substrate.	got7fsn_ti							dph	2016-09-07T16:30:48Z						molecular_function											owl:Class	
GO:0061783	biolink:NamedThing	peptidoglycan muralytic activity	A catalytic activity that contributes to the degradation of peptidoglycan.	got7fsn_ti							dph	2016-09-07T15:47:49Z						molecular_function											owl:Class	
GO:0052680	biolink:NamedThing	epi-isozizaene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.	got7fsn_ti	(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epi-isozizaene-forming] activity											KEGG_REACTION:R07830|MetaCyc:RXN-9349|RHEA:25992|EC:4.2.3.37		molecular_function											owl:Class	
GO:0009560	biolink:NamedThing	embryo sac egg cell differentiation	The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	female gamete generation|female gametophyte egg cell differentiation										GO:0048233			biological_process											owl:Class	
GO:0042254	biolink:NamedThing	ribosome biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.	got7fsn_ti	ribosome biogenesis and assembly										GO:0007046			biological_process											owl:Class	
GO:0022613	biolink:NamedThing	ribonucleoprotein complex biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.	got7fsn_ti	ribonucleoprotein complex biogenesis and assembly|RNA-protein complex biogenesis													biological_process											owl:Class	
GO:0007292	biolink:NamedThing	female gamete generation	Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.	got7fsn_ti														biological_process											owl:Class	
GO:0071160	biolink:NamedThing	cyanophycin synthetase activity (L-aspartate-adding)	Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp.	got7fsn_ti							mah	2009-11-17T05:18:17Z				RHEA:13277|EC:6.3.2.29		molecular_function											owl:Class	
GO:0043860	biolink:NamedThing	cyanophycin synthetase activity	Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).	got7fsn_ti	cphA											EC:6.3.1.-		molecular_function											owl:Class	
GO:0003320	biolink:NamedThing	heart rudiment involution	The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube.	got7fsn_ti							dph	2009-10-27T09:29:24Z						biological_process											owl:Class	
GO:0003152	biolink:NamedThing	morphogenesis of an epithelial fold involved in embryonic heart tube formation	The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.	got7fsn_ti							tb	2009-09-23T10:10:24Z						biological_process											owl:Class	
GO:0001569	biolink:NamedThing	branching involved in blood vessel morphogenesis	The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.	got7fsn_ti	patterning of blood vessels													biological_process											owl:Class	
GO:0023058	biolink:NamedThing	adaptation of signaling pathway	The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.	got7fsn_ti	adaptation of signalling pathway							2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0052611	biolink:NamedThing	beta-carotene 3-hydroxylase activity	Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O.	got7fsn_ti	carotene beta-ring hydroxylase activity|beta-carotene hydroxylase activity|beta-carotene 3-hydroxylase activity											MetaCyc:RXN-8025|RHEA:30323		molecular_function											owl:Class	
GO:0005982	biolink:NamedThing	starch metabolic process	The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose.	got7fsn_ti	starch metabolism													biological_process											owl:Class	
GO:0006190	biolink:NamedThing	inosine salvage	Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis.	got7fsn_ti	adenine, hypoxanthine and their nucleoside salvage|guanine, xanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0045129	biolink:NamedThing	NAD-independent histone deacetylase activity	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction does not require the presence of NAD, and represents the removal of an acetyl group from a histone.	got7fsn_ti	AcuC													molecular_function											owl:Class	
GO:0004407	biolink:NamedThing	histone deacetylase activity	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.	got7fsn_ti												EC:3.5.1.98|RHEA:58196|Reactome:R-HSA-3769447|Reactome:R-HSA-3782637|Reactome:R-HSA-2545253|Reactome:R-HSA-3782655|Reactome:R-HSA-427514|Reactome:R-HSA-433672|MetaCyc:3.5.1.98-RXN|Reactome:R-HSA-3777129|Reactome:R-HSA-6805650|Reactome:R-HSA-2545203		molecular_function											owl:Class	
GO:0002065	biolink:NamedThing	columnar/cuboidal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.	got7fsn_ti														biological_process											owl:Class	
GO:0030855	biolink:NamedThing	epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.	got7fsn_ti														biological_process											owl:Class	
GO:0003238	biolink:NamedThing	conus arteriosus development	The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.	got7fsn_ti							dph	2009-10-13T11:20:57Z						biological_process											owl:Class	
GO:0050283	biolink:NamedThing	serine-sulfate ammonia-lyase activity	Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate.	got7fsn_ti	serine-sulphate ammonia-lyase activity|(L-SOS)lyase activity|L-serine-O-sulfate ammonia-lyase (pyruvate-forming)											MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN|EC:4.3.1.10|RHEA:15605		molecular_function											owl:Class	
GO:0034654	biolink:NamedThing	nucleobase-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.	got7fsn_ti	nucleobase, nucleoside, nucleotide and nucleic acid anabolism|nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis|nucleobase, nucleoside, nucleotide and nucleic acid synthesis|nucleobase, nucleoside, nucleotide and nucleic acid formation													biological_process											owl:Class	
GO:0097747	biolink:NamedThing	RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.	got7fsn_ti							pr	2016-12-02T11:48:55Z						molecular_function											owl:Class	
GO:0015322	biolink:NamedThing	secondary active oligopeptide transmembrane transporter activity	Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.	got7fsn_ti	oligopeptide porter activity													molecular_function											owl:Class	
GO:0052845	biolink:NamedThing	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity	Catalysis of the reaction: inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.	got7fsn_ti							ai	2011-12-05T10:59:20Z				MetaCyc:RXN-10964		molecular_function											owl:Class	
GO:0052842	biolink:NamedThing	inositol diphosphate pentakisphosphate diphosphatase activity	Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate.	got7fsn_ti							ai	2011-11-29T04:14:22Z				Reactome:R-HSA-1855198|KEGG_REACTION:R05779|Reactome:R-HSA-2023971|RHEA:22384|EC:3.6.1.52		molecular_function											owl:Class	
GO:0036374	biolink:NamedThing	glutathione hydrolase activity	Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate.	got7fsn_ti	glutathionase activity|gamma-glutamyltranspeptidase activity						bf	2013-05-07T09:58:07Z				Reactome:R-HSA-5602984|Reactome:R-HSA-9035966|Reactome:R-HSA-5433072|Reactome:R-HSA-9026916|Reactome:R-HSA-8943279|EC:3.4.19.13|RHEA:28807|Reactome:R-HSA-9026927|Reactome:R-HSA-9026907|Reactome:R-HSA-9026757|Reactome:R-HSA-9026912|Reactome:R-HSA-1222712|KEGG_REACTION:R00494|MetaCyc:RXN-12618|Reactome:R-HSA-266046		molecular_function											owl:Class	
GO:0008242	biolink:NamedThing	omega peptidase activity	Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes.	got7fsn_ti	peptidase activity, acting on peptides containing modified amino acids											EC:3.4.19.2|MetaCyc:3.4.19.9-RXN|EC:3.4.19.-|EC:3.4.19.9|MetaCyc:PEPTIDYL-GLYCINAMIDASE-RXN		molecular_function											owl:Class	
GO:0004147	biolink:NamedThing	dihydrolipoamide branched chain acyltransferase activity	Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide, where the acyl group is a branched chain.	got7fsn_ti	dihydrolipoamide branched chain transacylase activity													molecular_function											owl:Class	
GO:0030523	biolink:NamedThing	dihydrolipoamide S-acyltransferase activity	Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide.	got7fsn_ti												EC:2.3.1.12		molecular_function											owl:Class	
GO:0034093	biolink:NamedThing	positive regulation of maintenance of sister chromatid cohesion	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.	got7fsn_ti														biological_process											owl:Class	
GO:0045876	biolink:NamedThing	positive regulation of sister chromatid cohesion	Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion.	got7fsn_ti	upregulation of sister chromatid cohesion|stimulation of sister chromatid cohesion|up regulation of sister chromatid cohesion|activation of sister chromatid cohesion|up-regulation of sister chromatid cohesion													biological_process											owl:Class	
GO:0022870	biolink:NamedThing	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	mannose PTS transporter activity													molecular_function											owl:Class	
GO:0102976	biolink:NamedThing	versiconal reductase activity	Catalysis of the reaction: versiconol + NADP <=> versiconal hemiacetal + NADPH + H+.	got7fsn_ti												RHEA:35699|MetaCyc:RXN-9491|EC:1.1.1.353		molecular_function											owl:Class	
GO:0080117	biolink:NamedThing	secondary growth	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium.	got7fsn_ti	cambial secondary growth				Occurs in vascular plants, including gymnosperms and most dicotyledons. Commonly supplemented by activity of the cork cambium or phellogen (PO:0005599). Monocotyledons do not have secondary growth, but may undergo primary thickening (GO:0080192) or secondary thickening (GO:0080191), which can give the appearance of secondary growth. Primary and secondary growth can occur simultaneously in the same organism.		dhl	2009-04-27T03:36:28Z						biological_process											owl:Class	
GO:0080190	biolink:NamedThing	lateral growth	Growth of a plant axis (shoot axis or root) that originates from a lateral meristem.	got7fsn_ti					Includes thickening of plant axes (PO:0025004) due to the activity of a cambium (PO:0005597), known as secondary growth and found in most gymnosperms and dicotyledons, a primary thickening meristem (PO:0005039) as found in many monocotyledons, some ferns and some cycads, or secondary thickening meristem, (PO:0025414) as found in some monocotyledons.		dhl	2012-12-06T15:42:28Z						biological_process											owl:Class	
GO:0001741	biolink:NamedThing	XY body	A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.	got7fsn_ti														cellular_component											owl:Class	
GO:0003207	biolink:NamedThing	cardiac chamber formation	The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.	got7fsn_ti	heart chamber formation						dph	2009-10-13T09:29:13Z						biological_process											owl:Class	
GO:0031929	biolink:NamedThing	TOR signaling	A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.	got7fsn_ti	TOR signalling pathway|TOR signal transduction|TOR signaling cascade|target of rapamycin signaling pathway|TOR signaling pathway|target of rapamycin signalling pathway				Note that this term should not be confused with 'torso signaling pathway ; GO:0008293', although torso is abbreviated 'tor'.									biological_process											owl:Class	
GO:0035556	biolink:NamedThing	intracellular signal transduction	The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	got7fsn_ti	protein kinase cascade|intracellular signaling pathway|intracellular signal transduction pathway|intracellular protein kinase cascade|signal transmission via intracellular cascade|intracellular signaling cascade|intracellular signaling chain|signal transduction via intracellular signaling cascade						bf	2010-05-14T01:14:37Z			GO:0007242|GO:0023013|GO:0007243|GO:0023034			biological_process											owl:Class	
GO:0038062	biolink:NamedThing	protein tyrosine kinase collagen receptor activity	Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	got7fsn_ti	collagen RTK activity|discoidin domain receptor						bf	2012-01-18T01:38:40Z						molecular_function											owl:Class	
GO:0038064	biolink:NamedThing	collagen receptor activity	Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	transmembrane collagen receptor activity						bf	2012-01-18T01:52:42Z						molecular_function											owl:Class	
GO:0070251	biolink:NamedThing	pristanate-CoA ligase activity	Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA.	got7fsn_ti	pristanate:CoA ligase (AMP-forming)|pristanoyl-CoA ligase activity											RHEA:47264|Reactome:R-HSA-389632		molecular_function											owl:Class	
GO:1990649	biolink:NamedThing	inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate.	got7fsn_ti							al	2015-02-23T11:12:10Z						molecular_function											owl:Class	
GO:0052743	biolink:NamedThing	inositol tetrakisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate.	got7fsn_ti							ai	2011-09-14T01:31:39Z						molecular_function											owl:Class	
GO:0031899	biolink:NamedThing	chromoplast inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma.	got7fsn_ti														cellular_component											owl:Class	
GO:0040030	biolink:NamedThing	regulation of molecular function, epigenetic	Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.	got7fsn_ti	regulation of protein activity, epigenetic													biological_process											owl:Class	
GO:0065009	biolink:NamedThing	regulation of molecular function	Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.	got7fsn_ti	regulation of a molecular function													biological_process											owl:Class	
GO:0042017	biolink:NamedThing	interleukin-22 binding	Binding to interleukin-22.	got7fsn_ti	IL-22 binding													molecular_function											owl:Class	
GO:1903707	biolink:NamedThing	negative regulation of hemopoiesis	Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.	got7fsn_ti	inhibition of blood cell formation|negative regulation of blood cell formation|inhibition of blood cell biosynthesis|down-regulation of blood cell biosynthesis|down-regulation of haemopoiesis|negative regulation of hematopoiesis|inhibition of hemopoiesis|downregulation of haemopoiesis|negative regulation of haemopoiesis|down regulation of hematopoiesis|down regulation of hemopoiesis|negative regulation of blood cell biosynthesis|down regulation of blood cell formation|downregulation of hemopoiesis|down regulation of haemopoiesis|downregulation of blood cell formation|inhibition of haemopoiesis|downregulation of hematopoiesis|inhibition of hematopoiesis|down-regulation of blood cell formation|down-regulation of hemopoiesis|down regulation of blood cell biosynthesis|downregulation of blood cell biosynthesis|down-regulation of hematopoiesis				An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.		pad	2014-12-04T15:34:21Z						biological_process											owl:Class	
GO:0007469	biolink:NamedThing	antennal development	The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.	got7fsn_ti														biological_process											owl:Class	
GO:0035114	biolink:NamedThing	imaginal disc-derived appendage morphogenesis	The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0085041	biolink:NamedThing	arbuscule	Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange.	got7fsn_ti					See also: periarbuscular membrane ; GO:0085042.		jl	2010-07-27T04:29:03Z						cellular_component											owl:Class	
GO:0085035	biolink:NamedThing	haustorium	A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane.	got7fsn_ti					See also: extrahaustorial matrix ; GO:0085036 and extrahaustorial membrane ; GO:0085037.		jl	2010-07-27T03:42:24Z						cellular_component											owl:Class	
GO:0002150	biolink:NamedThing	hypochlorous acid catabolic process	The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.	got7fsn_ti	HOCl catabolic process|hypochlorite catabolic process|hypochlorous acid catabolism|HClO catabolic process						hjd	2009-10-13T10:36:09Z						biological_process											owl:Class	
GO:0042000	biolink:NamedThing	translocation of peptides or proteins into host	The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	translocation of peptides or proteins into other organism during symbiotic interaction|transport of peptides or proteins into host|translocation of peptides or proteins into other organism involved in symbiotic interaction|transport of peptides or proteins into other organism during symbiotic interaction										GO:0051808			biological_process											owl:Class	
GO:0007485	biolink:NamedThing	imaginal disc-derived male genitalia development	The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.	got7fsn_ti	male genital development													biological_process											owl:Class	
GO:0007484	biolink:NamedThing	imaginal disc-derived genitalia development	The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.	got7fsn_ti	genital development													biological_process											owl:Class	
GO:0018859	biolink:NamedThing	4-hydroxybenzoate-CoA ligase activity	Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.	got7fsn_ti	4-hydroxybenzoate:CoA ligase (AMP-forming)|4-hydroxybenzoate-coenzyme A ligase (AMP-forming)|4-hydroxybenzoyl-CoA ligase activity|4-hydroxybenzoate-CoA synthetase activity|4-hydroxybenzoyl coenzyme A synthetase activity											RHEA:23116|UM-BBD_reactionID:r0156|EC:6.2.1.27|MetaCyc:4-HYDROXYBENZOATE--COA-LIGASE-RXN|KEGG_REACTION:R01300		molecular_function											owl:Class	
GO:0018173	biolink:NamedThing	peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine	The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine.	got7fsn_ti	peptidyl-1-thioglycine synthesis from peptidyl-glycine|peptidyl-1-thioglycine anabolism from peptidyl-glycine|peptidyl-1-thioglycine formation from peptidyl-glycine											RESID:AA0265		biological_process											owl:Class	
GO:0043316	biolink:NamedThing	cytotoxic T cell degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.	got7fsn_ti	cytotoxic T-cell granule exocytosis|cytotoxic T lymphocyte degranulation|cytotoxic T-lymphocyte degranulation|cytotoxic T cell granule exocytosis|cytotoxic T-lymphocyte granule exocytosis|cytotoxic T lymphocyte granule exocytosis|cytotoxic T-cell degranulation													biological_process											owl:Class	
GO:0002286	biolink:NamedThing	T cell activation involved in immune response	The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	T lymphocyte activation during immune response|T-cell activation during immune response|T cell activation during immune response|T-lymphocyte activation during immune response													biological_process											owl:Class	
GO:0046331	biolink:NamedThing	lateral inhibition	Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.	got7fsn_ti														biological_process											owl:Class	
GO:0044503	biolink:NamedThing	modulation of G protein-coupled receptor activity in other organism	The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism.	got7fsn_ti	modulation of G-protein coupled receptor activity in other organism						jl	2012-02-23T04:20:07Z						biological_process											owl:Class	
GO:0044504	biolink:NamedThing	modulation of receptor activity in other organism	The process in which an organism effects a change in the activity of a receptor in a second organism.	got7fsn_ti							jl	2012-02-23T04:21:41Z						biological_process											owl:Class	
GO:0090573	biolink:NamedThing	RNA polymerase IV transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter.	got7fsn_ti							tb	2014-05-09T13:26:16Z						cellular_component											owl:Class	
GO:0009931	biolink:NamedThing	calcium-dependent protein serine/threonine kinase activity	Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.	got7fsn_ti					These reactions are dependent on the presence of calcium ions.									molecular_function											owl:Class	
GO:0010857	biolink:NamedThing	calcium-dependent protein kinase activity	Calcium-dependent catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.	got7fsn_ti					This reaction requires the presence of calcium.							Reactome:R-HSA-9005561|Reactome:R-HSA-8986937		molecular_function											owl:Class	
GO:0001006	biolink:NamedThing	RNA polymerase III type 3 promoter sequence-specific DNA binding	Binding to a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.	got7fsn_ti	RNA polymerase III type 3 promoter DNA binding						krc	2010-08-18T06:02:26Z			GO:0001032			molecular_function											owl:Class	
GO:0001016	biolink:NamedThing	RNA polymerase III transcription regulatory region sequence-specific DNA binding	Binding to a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.	got7fsn_ti	RNA polymerase III regulatory region DNA binding						krc	2010-08-19T09:36:17Z						molecular_function											owl:Class	
GO:0033612	biolink:NamedThing	receptor serine/threonine kinase binding	Binding to a receptor that possesses protein serine/threonine kinase activity.	got7fsn_ti	transmembrane receptor protein serine/threonine kinase ligand binding													molecular_function											owl:Class	
GO:0060037	biolink:NamedThing	pharyngeal system development	The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.	got7fsn_ti														biological_process											owl:Class	
GO:0048731	biolink:NamedThing	system development	The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.	got7fsn_ti														biological_process											owl:Class	
GO:1900558	biolink:NamedThing	austinol metabolic process	The chemical reactions and pathways involving austinol.	got7fsn_ti	austinol metabolism						di	2012-05-15T06:26:58Z						biological_process											owl:Class	
GO:1990593	biolink:NamedThing	nascent polypeptide-associated complex binding	Binding to nascent polypeptide-associated complex, a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.	got7fsn_ti	NAC binding|NACA binding						mcc	2014-12-15T22:20:45Z						molecular_function											owl:Class	
GO:0102321	biolink:NamedThing	2,2'-hydroxybiphenyl monooxygenase activity	Catalysis of the reaction: biphenyl-2,2'-diol + O2 + NADH + H+ <=> biphenyl-2,2',3-triol + H2O + NAD.	got7fsn_ti												EC:1.14.13.44|MetaCyc:MONOMER-17239|RHEA:63512		molecular_function											owl:Class	
GO:0110054	biolink:NamedThing	regulation of actin filament annealing	Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.	got7fsn_ti							kmv	2017-09-20T20:07:58Z						biological_process											owl:Class	
GO:0110053	biolink:NamedThing	regulation of actin filament organization	Any process that modulates the frequency, rate or extent of actin filament organization.	got7fsn_ti							kmv	2017-09-20T19:52:57Z						biological_process											owl:Class	
GO:0019824	biolink:NamedThing	P6 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes.	got7fsn_ti	peroxisome vesicle				Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', and 'P5 peroxisome ; GO:0019823'.									cellular_component											owl:Class	
GO:0005777	biolink:NamedThing	peroxisome	A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.	got7fsn_ti	peroxisomal|peroxisome vesicle										GO:0019818	NIF_Subcellular:sao499555322|Wikipedia:Peroxisome		cellular_component											owl:Class	
GO:1990861	biolink:NamedThing	Ubp3-Bre5 deubiquitination complex	A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p.	got7fsn_ti	Ubp3-Bre5 ubiquitin protease complex						rb	2015-09-24T17:56:53Z						cellular_component											owl:Class	
GO:0000045	biolink:NamedThing	autophagosome assembly	The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.	got7fsn_ti	PAS formation|autophagic vacuole assembly|autophagosome formation|autophagic vacuole formation|autophagosome biosynthesis													biological_process											owl:Class	
GO:0035074	biolink:NamedThing	pupation	The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.	got7fsn_ti	head eversion|prepupal-pupal transition											Wikipedia:Pupa		biological_process											owl:Class	
GO:0097043	biolink:NamedThing	histone H3-K56 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone.	got7fsn_ti							pr	2011-04-19T05:18:29Z						biological_process											owl:Class	
GO:0050285	biolink:NamedThing	sinapine esterase activity	Catalysis of the reaction: O-sinapoylcholine + H(2)O = choline + H(+) + sinapate.	got7fsn_ti	sinapoylcholine sinapohydrolase activity|aromatic choline esterase activity											RHEA:10016|EC:3.1.1.49|MetaCyc:SINAPINE-ESTERASE-RXN|KEGG_REACTION:R02381		molecular_function											owl:Class	
GO:0042149	biolink:NamedThing	cellular response to glucose starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.	got7fsn_ti														biological_process											owl:Class	
GO:0042922	biolink:NamedThing	neuromedin U receptor binding	Binding to one or more specific sites on a neuromedin U receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0031967	biolink:NamedThing	organelle envelope	A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.	got7fsn_ti														cellular_component											owl:Class	
GO:0030706	biolink:NamedThing	germarium-derived oocyte differentiation	The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster.	got7fsn_ti	oocyte cell differentiation													biological_process											owl:Class	
GO:0009994	biolink:NamedThing	oocyte differentiation	The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.	got7fsn_ti	oocyte cell differentiation													biological_process											owl:Class	
GO:0019135	biolink:NamedThing	deoxyhypusine monooxygenase activity	Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.	got7fsn_ti	deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)|DOHH activity|deoxyhypusine dioxygenase activity|deoxyhypusine hydroxylase activity											RHEA:14101|Reactome:R-HSA-204662|MetaCyc:DEOXYHYPUSINE-MONOOXYGENASE-RXN|EC:1.14.99.29		molecular_function											owl:Class	
GO:0002711	biolink:NamedThing	positive regulation of T cell mediated immunity	Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.	got7fsn_ti	upregulation of T cell mediated immunity|positive regulation of T-cell mediated immunity|up regulation of T cell mediated immunity|activation of T cell mediated immunity|positive regulation of T-lymphocyte mediated immunity|positive regulation of T lymphocyte mediated immunity|up-regulation of T cell mediated immunity|stimulation of T cell mediated immunity													biological_process											owl:Class	
GO:0052043	biolink:NamedThing	modification by symbiont of host cellular component	The process in which an organism effects a change in the structure or function of a host cellular component. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0010005	biolink:NamedThing	cortical microtubule, transverse to long axis	Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition.	got7fsn_ti														cellular_component											owl:Class	
GO:0055028	biolink:NamedThing	cortical microtubule	Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol.	got7fsn_ti														cellular_component											owl:Class	
GO:0042463	biolink:NamedThing	ocellus photoreceptor cell development	Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus.	got7fsn_ti	non-eye photoreceptor development										GO:0001749			biological_process											owl:Class	
GO:0042461	biolink:NamedThing	photoreceptor cell development	Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.	got7fsn_ti	photoreceptor morphogenesis										GO:0046531			biological_process											owl:Class	
GO:0046027	biolink:NamedThing	phospholipid:diacylglycerol acyltransferase activity	Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol.	got7fsn_ti	PDAT activity|phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase activity											EC:2.3.1.158|MetaCyc:2.3.1.158-RXN|RHEA:14057		molecular_function											owl:Class	
GO:2000255	biolink:NamedThing	negative regulation of male germ cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.	got7fsn_ti							dph	2010-11-18T09:29:47Z						biological_process											owl:Class	
GO:0018745	biolink:NamedThing	epoxide hydrolase A activity	Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol.	got7fsn_ti												UM-BBD_enzymeID:e0049|EC:3.3.2.-		molecular_function											owl:Class	
GO:0000226	biolink:NamedThing	microtubule cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.	got7fsn_ti	microtubule cytoskeleton organisation|microtubule dynamics|microtubule cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:0034911	biolink:NamedThing	phthalate 3,4-dioxygenase activity	Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+.	got7fsn_ti												UM-BBD_reactionID:r1444|EC:1.14.12.-		molecular_function											owl:Class	
GO:0007207	biolink:NamedThing	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	muscarinic acetylcholine receptor, phospholipase C activating pathway|activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway|activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway|muscarinic receptor signaling pathway via activation of PLC|activation of phospholipase C activity by muscarinic acetylcholine receptor signalling pathway|phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway													biological_process											owl:Class	
GO:0007213	biolink:NamedThing	G protein-coupled acetylcholine receptor signaling pathway	Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	acetylcholine receptor signalling, muscarinic pathway|muscarinic acetylcholine receptor signaling pathway|G-protein coupled acetylcholine receptor signaling pathway													biological_process											owl:Class	
GO:0033273	biolink:NamedThing	response to vitamin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0097706	biolink:NamedThing	vascular endothelial cell response to oscillatory fluid shear stress	Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell.	got7fsn_ti	blood vessel endothelial cell response to oscillatory fluid shear stress						pr	2016-01-27T14:25:34Z						biological_process											owl:Class	
GO:0097704	biolink:NamedThing	cellular response to oscillatory fluid shear stress	Any response to oscillatory fluid shear stress that occurs at the level of a cell.	got7fsn_ti							pr	2016-01-27T14:20:54Z						biological_process											owl:Class	
GO:0051047	biolink:NamedThing	positive regulation of secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.	got7fsn_ti	upregulation of secretion|up-regulation of secretion|up regulation of secretion|activation of secretion|stimulation of secretion													biological_process											owl:Class	
GO:0050580	biolink:NamedThing	2,5-didehydrogluconate reductase activity	Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.	got7fsn_ti	2-dehydro-D-gluconate:NADP+ 2-oxidoreductase activity|YqhE reductase|2,5-diketo-D-gluconate reductase activity											EC:1.1.1.274|MetaCyc:1.1.1.274-RXN|RHEA:23828		molecular_function											owl:Class	
GO:0050695	biolink:NamedThing	benzoylformate decarboxylase activity	Catalysis of the reaction: benzoylformate = benzaldehyde + CO2.	got7fsn_ti	phenylglyoxylate decarboxylase activity|benzoylformate carboxy-lyase activity|benzoylformate carboxy-lyase (benzaldehyde-forming)											UM-BBD_reactionID:r1049|MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN|EC:4.1.1.7|RHEA:23368		molecular_function											owl:Class	
GO:0021942	biolink:NamedThing	radial glia guided migration of Purkinje cell	The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer.	got7fsn_ti														biological_process											owl:Class	
GO:0021932	biolink:NamedThing	hindbrain radial glia guided cell migration	The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain.	got7fsn_ti														biological_process											owl:Class	
GO:0050632	biolink:NamedThing	propionyl-CoA C2-trimethyltridecanoyltransferase activity	Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.	got7fsn_ti	sterol carrier protein|sterol carrier protein X-related thiolase activity|3-oxopristanoyl-CoA thiolase activity|oxopristanoyl-CoA thiolase activity|peroxisomal 3-oxoacyl coenzyme A thiolase|4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase activity|peroxisome sterol carrier protein thiolase|3-oxopristanoyl-CoA hydrolase activity|propionyl-CoA C(2)-trimethyltridecanoyltransferase activity|4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA 2-C-4,8,12-trimethyltridecanoyltransferase activity|SCPx										GO:0004770	Reactome:R-HSA-2066781|RHEA:10408|MetaCyc:2.3.1.154-RXN|Reactome:R-HSA-390224|KEGG_REACTION:R05330|Reactome:R-HSA-193533|EC:2.3.1.176|Reactome:R-HSA-192341		molecular_function											owl:Class	
GO:0070985	biolink:NamedThing	transcription factor TFIIK complex	A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.	got7fsn_ti	TFIIK complex|cyclin H-CDK7 complex|Mcs6/Mcs2/Pmh1 complex						mah	2009-10-27T04:19:37Z						cellular_component											owl:Class	
GO:0070117	biolink:NamedThing	organellar chromatophore thylakoid lumen	The volume enclosed by an organellar chromatophore thylakoid membrane.	got7fsn_ti	Paulinella-type chromatophore thylakoid lumen													cellular_component											owl:Class	
GO:0061119	biolink:NamedThing	regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.	got7fsn_ti							dph	2010-05-17T07:53:58Z						biological_process											owl:Class	
GO:0061118	biolink:NamedThing	regulation of positive chemotaxis to cAMP	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.	got7fsn_ti							dph	2010-05-17T07:47:47Z						biological_process											owl:Class	
GO:0019573	biolink:NamedThing	D-arabinose catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate.	got7fsn_ti	D-arabinose breakdown to xylulose 5-phosphate|D-arabinose degradation to xylulose 5-phosphate											MetaCyc:DARABCAT-PWY		biological_process											owl:Class	
GO:0046905	biolink:NamedThing	15-cis-phytoene synthase activity	Catalysis of the reaction: 2 geranylgeranyl diphosphate -> 15-cis-phytoene + 2 diphosphate.	got7fsn_ti	phytoene synthase activity	https://github.com/geneontology/go-ontology/issues/21165			Note that this should not be confused with 'geranylgeranyl-diphosphate geranylgeranyltransferase activity ; GO:0016767', EC:2.5.1.32. This activity is the second part of the formation of phytoene from geranylgeranyl-diphosphate, the first stage of which is catalyzed by EC:2.5.1.32.							RHEA:34479		molecular_function											owl:Class	
GO:0097209	biolink:NamedThing	epidermal lamellar body	A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.	got7fsn_ti							pr	2012-01-04T02:34:27Z						cellular_component											owl:Class	
GO:0042599	biolink:NamedThing	lamellar body	A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.	got7fsn_ti	Odland body|lamellar granule|membrane-coating granule|keratinosome											NIF_Subcellular:sao1379604862		cellular_component											owl:Class	
GO:0008328	biolink:NamedThing	ionotropic glutamate receptor complex	A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.	got7fsn_ti														cellular_component											owl:Class	
GO:1990426	biolink:NamedThing	mitotic recombination-dependent replication fork processing	Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.	got7fsn_ti	homologous recombination-dependent replication fork processing|homologous recombination dependent replication fork recovery						mah	2014-07-24T09:42:54Z						biological_process											owl:Class	
GO:0006421	biolink:NamedThing	asparaginyl-tRNA aminoacylation	The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0006418	biolink:NamedThing	tRNA aminoacylation for protein translation	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid  group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.	got7fsn_ti	tRNA charging											MetaCyc:TRNA-CHARGING-PWY		biological_process											owl:Class	
GO:0004656	biolink:NamedThing	procollagen-proline 4-dioxygenase activity	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.	got7fsn_ti	proline hydroxylase activity|protocollagen proline 4-hydroxylase activity|protocollagen proline hydroxylase activity|protocollagen hydroxylase activity|prolylprotocollagen dioxygenase activity|peptidyl proline hydroxylase activity|procollagen-proline,2-oxoglutarate-4-dioxygenase activity|prolyl hydroxylase activity|proline,2-oxoglutarate 4-dioxygenase activity|collagen proline hydroxylase activity|procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity|prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity|prolylprotocollagen hydroxylase activity|protocollagen prolyl hydroxylase activity|proline, 2-oxoglutarate dioxygenase activity|hydroxylase, collagen proline activity|protocollagen proline dioxygenase activity|prolyl 4-hydroxylase activity|proline protocollagen hydroxylase activity											EC:1.14.11.2|MetaCyc:1.14.11.2-RXN|KEGG_REACTION:R03219|RHEA:18945|Reactome:R-HSA-1650808		molecular_function											owl:Class	
GO:0019798	biolink:NamedThing	procollagen-proline dioxygenase activity	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.	got7fsn_ti														molecular_function											owl:Class	
GO:0019350	biolink:NamedThing	teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.	got7fsn_ti	teichoic acid formation|teichoic acid anabolism|teichoic acid synthesis|teichoic acid biosynthesis											MetaCyc:TEICHOICACID-PWY		biological_process											owl:Class	
GO:0032792	biolink:NamedThing	negative regulation of CREB transcription factor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB.	got7fsn_ti	inhibition of CREB transcription factor|CREB inhibitor													biological_process											owl:Class	
GO:0043433	biolink:NamedThing	negative regulation of DNA-binding transcription factor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	got7fsn_ti	negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of androgen receptor activity|negative regulation of DNA binding transcription factor activity|negative regulation of transcription factor activity|inhibition of transcription factor activity|downregulation of transcription factor activity|down regulation of transcription factor activity|down-regulation of transcription factor activity|negative regulation of thyroid hormone receptor activity							2011-07-15T10:56:12Z			GO:1904168|GO:2000824			biological_process											owl:Class	
GO:0042718	biolink:NamedThing	yolk granule	Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.	got7fsn_ti														cellular_component											owl:Class	
GO:0016404	biolink:NamedThing	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.	got7fsn_ti	NAD-specific 15-hydroxyprostaglandin dehydrogenase activity|prostaglandin dehydrogenase activity|15-hydroxyprostaglandin dehydrogenase activity|15-hydroxyprostanoic dehydrogenase activity|11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity|NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)|15-OH-PGDH|(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity											Reactome:R-HSA-9023968|MetaCyc:1.1.1.141-RXN|EC:1.1.1.141|RHEA:11876|Reactome:R-HSA-9024766|Reactome:R-HSA-2161779|Reactome:R-HSA-2161662		molecular_function											owl:Class	
GO:0048704	biolink:NamedThing	embryonic skeletal system morphogenesis	The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.	got7fsn_ti	embryonic skeletal morphogenesis													biological_process											owl:Class	
GO:0048705	biolink:NamedThing	skeletal system morphogenesis	The process in which the anatomical structures of the skeleton are generated and organized.	got7fsn_ti	skeletal morphogenesis													biological_process											owl:Class	
GO:1990246	biolink:NamedThing	uniplex complex	A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE.	got7fsn_ti	mitochondrial uniporter complex|mitochondrial uniporter holocomplex						sp	2013-12-04T06:44:35Z						cellular_component											owl:Class	
GO:0034704	biolink:NamedThing	calcium channel complex	An ion channel complex through which calcium ions pass.	got7fsn_ti														cellular_component											owl:Class	
GO:0051293	biolink:NamedThing	establishment of spindle localization	The directed movement of the spindle to a specific location in the cell.	got7fsn_ti	spindle positioning|establishment of spindle localisation													biological_process											owl:Class	
GO:0097456	biolink:NamedThing	terminal loop	Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath.	got7fsn_ti	terminal loop of Schwann cell						pr	2012-12-19T13:04:06Z				NIF_Subcellular:sao924713546		cellular_component											owl:Class	
GO:0004567	biolink:NamedThing	beta-mannosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.	got7fsn_ti	beta-D-mannosidase activity|mannanase activity|beta-mannoside mannohydrolase activity|mannase activity|beta-D-mannoside mannohydrolase activity|exo-beta-D-mannanase activity											Reactome:R-HSA-8853710|MetaCyc:3.2.1.25-RXN|EC:3.2.1.25		molecular_function											owl:Class	
GO:0015923	biolink:NamedThing	mannosidase activity	Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0001099	biolink:NamedThing	basal RNA polymerase II transcription machinery binding	Binding to a component of the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.	got7fsn_ti	basal RNAP II transcription machinery binding				Note that the definition of basal, or general, transcription factors has typically been done at a small number of well characterized activator-independent promoters. At an activator-dependent promoter, one or more additional factors are generally required in addition to the basal factors.		krc	2010-11-24T12:54:33Z						molecular_function											owl:Class	
GO:0004298	biolink:NamedThing	threonine-type endopeptidase activity	Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.	got7fsn_ti	multicatalytic proteinase (complex)|tricorn proteinase|proteasome endopeptidase complex|prosome|multicatalytic endopeptidase complex|tricorn protease|26S protease|MCP|ingensin|large multicatalytic protease|alkaline protease|threonine endopeptidase activity|lens neutral proteinase|multicatalytic proteinase											EC:3.4.25.-		molecular_function											owl:Class	
GO:0004175	biolink:NamedThing	endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.	got7fsn_ti	elastase activity|endoprotease activity|proteasome endopeptidase activity|proteinase										GO:0016809	Reactome:R-HSA-6784676|Reactome:R-HSA-4608855|Reactome:R-HSA-2130282|Reactome:R-HSA-5668520|Reactome:R-HSA-68825|Reactome:R-HSA-5362448|Reactome:R-HSA-3640874|Reactome:R-HSA-9008475|Reactome:R-HSA-5610758|Reactome:R-HSA-180573|Reactome:R-HSA-174203|Reactome:R-HSA-4641260|Reactome:R-HSA-8849797|Reactome:R-HSA-8934819|Reactome:R-HSA-450466|MetaCyc:RXN0-5195|Reactome:R-HSA-187574|Reactome:R-HSA-8854044|Reactome:R-HSA-188191|Reactome:R-HSA-8952408|Reactome:R-HSA-68948|Reactome:R-HSA-74730|Reactome:R-HSA-5607731|Reactome:R-HSA-5610757|Reactome:R-HSA-5658430|Reactome:R-HSA-5610760|Reactome:R-HSA-8939801|Reactome:R-HSA-1236935|Reactome:R-HSA-180603|Reactome:R-HSA-5358340|Reactome:R-HSA-983150|Reactome:R-HSA-174058|Reactome:R-HSA-174255|Reactome:R-HSA-264458|Reactome:R-HSA-5687112|Reactome:R-HSA-8866553|Reactome:R-HSA-5693081|Reactome:R-HSA-174105|Reactome:R-HSA-5387392|Reactome:R-HSA-9008110|Reactome:R-HSA-1168640|Reactome:R-HSA-209061|Reactome:R-HSA-9614271|Reactome:R-HSA-5635868|Reactome:R-HSA-8850992|Reactome:R-HSA-353125|Reactome:R-HSA-9010096|Reactome:R-HSA-4641256|Reactome:R-HSA-5610754|Reactome:R-HSA-3928656|Reactome:R-HSA-75825|Reactome:R-HSA-1234159|Reactome:R-HSA-69600|Reactome:R-HSA-5607724|Reactome:R-HSA-8866858|Reactome:R-HSA-8852354|Reactome:R-HSA-5635854|Reactome:R-HSA-193682|Reactome:R-HSA-9604642|Reactome:R-HSA-69016|Reactome:R-HSA-174202|EC:3.4.99.-|Reactome:R-HSA-8854071|Reactome:R-HSA-8957265|Reactome:R-HSA-211715|Reactome:R-HSA-983158|Reactome:R-HSA-9009362|Reactome:R-HSA-9011313|Reactome:R-HSA-5668481|Reactome:R-HSA-2213200|Reactome:R-HSA-6784628|Reactome:R-HSA-1433374|Reactome:R-HSA-1504193|Reactome:R-HSA-1236970|Reactome:R-HSA-5358460|Reactome:R-HSA-1251997		molecular_function											owl:Class	
GO:0000729	biolink:NamedThing	DNA double-strand break processing	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.	got7fsn_ti														biological_process											owl:Class	
GO:0034497	biolink:NamedThing	protein localization to phagophore assembly site	Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).	got7fsn_ti	protein localisation to phagophore assembly site|protein localization to pre-autophagosomal structure|protein localization to PAS													biological_process											owl:Class	
GO:0070518	biolink:NamedThing	alpha4-beta1 integrin-CD53 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.	got7fsn_ti	ITGA4-ITGB1-CD53 complex													cellular_component											owl:Class	
GO:0002051	biolink:NamedThing	osteoblast fate commitment	The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.	got7fsn_ti														biological_process											owl:Class	
GO:0001222	biolink:NamedThing	transcription corepressor binding	Binding to a transcription corepressor, a protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.	got7fsn_ti	RNA polymerase II transcription corepressor binding	https://github.com/geneontology/go-ontology/issues/19354					krc	2012-04-16T03:27:26Z			GO:0001226			molecular_function											owl:Class	
GO:0001221	biolink:NamedThing	transcription coregulator binding	Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.	got7fsn_ti	RNA polymerase II transcription coregulator binding|transcription cofactor binding|RNA polymerase II transcription cofactor binding	https://github.com/geneontology/go-ontology/issues/19354					krc	2012-04-16T03:19:05Z			GO:0001224			molecular_function											owl:Class	
GO:0014701	biolink:NamedThing	junctional sarcoplasmic reticulum membrane	The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0033017	biolink:NamedThing	sarcoplasmic reticulum membrane	The lipid bilayer surrounding the sarcoplasmic reticulum.	got7fsn_ti														cellular_component											owl:Class	
GO:0050016	biolink:NamedThing	kynurenine 7,8-hydroxylase activity	Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor.	got7fsn_ti	kynurenate 7,8-hydroxylase activity|kynurenic hydroxylase activity|kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|kynurenic acid hydroxylase activity											MetaCyc:KYNURENINE-78-HYDROXYLASE-RXN|EC:1.14.99.2|RHEA:11968		molecular_function											owl:Class	
GO:0050497	biolink:NamedThing	alkylthioltransferase activity	Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring alkylthio groups											EC:2.8.4.-		molecular_function											owl:Class	
GO:0016782	biolink:NamedThing	transferase activity, transferring sulphur-containing groups	Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring sulphur-containing groups	https://github.com/geneontology/go-ontology/issues/20486										EC:2.8.-.-		molecular_function											owl:Class	
GO:0052036	biolink:NamedThing	suppression by symbiont of host inflammatory response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition by symbiont of host inflammatory response|negative regulation by organism of inflammatory response of other organism involved in symbiotic interaction|down-regulation by symbiont of host inflammatory response|downregulation by symbiont of host inflammatory response|down regulation by symbiont of host inflammatory response|negative regulation by symbiont of host inflammatory response										GO:0052260			biological_process											owl:Class	
GO:0044414	biolink:NamedThing	suppression of host defenses by symbiont	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	down-regulation by organism of defense response of other organism during symbiotic interaction|inhibition by organism of defense response of other organism during symbiotic interaction|suppression of defense response of other organism|negative regulation by symbiont of host defense response|down-regulation by symbiont of host defense response|suppression of host defense response|suppression of defenses of other organism involved in symbiotic interaction|down regulation by organism of defense response of other organism during symbiotic interaction|suppression of defense response of other organism involved in symbiotic interaction|negative regulation of host defenses|negative regulation by organism of defense response of other organism involved in symbiotic interaction|negative regulation by organism of defense response of other organism during symbiotic interaction|downregulation by organism of defense response of other organism during symbiotic interaction|downregulation by symbiont of host defense response|down regulation by symbiont of host defense response|inhibition by symbiont of host defense response										GO:0052261|GO:0051833|GO:0052037			biological_process											owl:Class	
GO:0018685	biolink:NamedThing	alkane 1-monooxygenase activity	Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.	got7fsn_ti	alkane hydroxylase activity|lauric acid omega-hydroxylase activity|alkane 1-hydroxylase activity|1-hydroxylase activity|alkane monooxygenase activity|alkane,reduced-rubredoxin:oxygen 1-oxidoreductase activity|omega-hydroxylase activity|fatty acid omega-hydroxylase activity|fatty acid (omega-1)-hydroxylase activity										GO:0008393	RHEA:19341|EC:1.14.15.3|UM-BBD_enzymeID:e0022|MetaCyc:ALKANE-1-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0004876	biolink:NamedThing	complement component C3a receptor activity	Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	C3a anaphylatoxin receptor activity										GO:0004943			molecular_function											owl:Class	
GO:1901275	biolink:NamedThing	tartrate metabolic process	The chemical reactions and pathways involving tartrate.	got7fsn_ti	tartrate metabolism						yaf	2012-08-17T14:52:19Z						biological_process											owl:Class	
GO:0097556	biolink:NamedThing	left posteriolateral flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body.	got7fsn_ti	left posteriolateral cilium|left posterolateral cilium|left posterolateral flagellum				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:21:09Z						cellular_component											owl:Class	
GO:0097729	biolink:NamedThing	9+2 motile cilium	A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).	got7fsn_ti	motile 9+2 cilium|sperm flagellum|conventional motile cilium				This type of cilia may be present in solitary (so-called flagella, e.g. in sperm) or in multiple copies (so-called conventional motile cilia, e.g. in tracheal epithelium, ependyma or oviduct epithelium).		pr	2016-09-27T15:26:34Z						cellular_component											owl:Class	
GO:0021518	biolink:NamedThing	spinal cord commissural neuron specification	The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.	got7fsn_ti														biological_process											owl:Class	
GO:0015874	biolink:NamedThing	norepinephrine transport	The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.	got7fsn_ti	levarterenol transport|noradrenaline transport													biological_process											owl:Class	
GO:0051750	biolink:NamedThing	delta3,5-delta2,4-dienoyl-CoA isomerase activity	Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA.	got7fsn_ti	delta5-delta2,4-dienoyl-CoA isomerase activity|delta(3,5),delta(2,4)-dienoyl-coenzyme A isomerase activity										GO:0008416			molecular_function											owl:Class	
GO:0021969	biolink:NamedThing	corticospinal neuron axon guidance through the cerebral peduncle	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.	got7fsn_ti	corticospinal neuron axon pathfinding through the cerebral peduncle													biological_process											owl:Class	
GO:0034850	biolink:NamedThing	isooctane monooxygenase activity	Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol.	got7fsn_ti												UM-BBD_reactionID:r1269|EC:1.13.12.-		molecular_function											owl:Class	
GO:0042883	biolink:NamedThing	cysteine transport	The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-cysteine transport													biological_process											owl:Class	
GO:0097423	biolink:NamedThing	mitochondrion-associated adherens complex	An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans.	got7fsn_ti	mitochondrial adhaerens complex|MAC						pr	2012-11-07T13:38:50Z				NIF_Subcellular:sao1933817066		cellular_component											owl:Class	
GO:0004755	biolink:NamedThing	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity	Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = L-allysine + L-glutamate + H(+) + NADPH.	got7fsn_ti	epsilon-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming)|aminoadipic semialdehyde-glutamic reductase activity|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)|aminoadipate semialdehyde-glutamate reductase activity|saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase activity|saccharopine reductase activity|aminoadipic semialdehyde-glutamate reductase activity											EC:1.5.1.10|MetaCyc:RXN3O-127|RHEA:10020|KEGG_REACTION:R02315		molecular_function											owl:Class	
GO:0004753	biolink:NamedThing	saccharopine dehydrogenase activity	Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor.	got7fsn_ti	lysine-ketoglutarate reductase activity|lysine-2-oxoglutarate reductase activity													molecular_function											owl:Class	
GO:0004844	biolink:NamedThing	uracil DNA N-glycosylase activity	Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.	got7fsn_ti	uracil-DNA glycosylase activity											Reactome:R-HSA-110217|Reactome:R-HSA-110215		molecular_function											owl:Class	
GO:0051357	biolink:NamedThing	peptide cross-linking via 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one	The formation of a 2-keto-5-iminopiperazine protein chromophore cross-link from the alpha-amino nitrogen of residue n, a methionine, to the alpha-carboxyl carbon of residue n+1, a tyrosine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+2. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	got7fsn_ti	biosynthesis of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine|biosynthetic process of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine				Note that this predicted modification is now thought not to exist. See the biological process term 'peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine ; GO:0051359'.							RESID:AA0377		biological_process											owl:Class	
GO:0043655	biolink:NamedThing	host extracellular space	The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream.	got7fsn_ti	extracellular space of host|host extracellular space													cellular_component											owl:Class	
GO:0018995	biolink:NamedThing	host cellular component	Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.	got7fsn_ti	host organism											Wikipedia:Host_(biology)		cellular_component											owl:Class	
GO:0018073	biolink:NamedThing	protein bromination	The addition of one or more bromine atoms to an amino acid residue in a protein.	got7fsn_ti	protein amino acid bromination													biological_process											owl:Class	
GO:0052403	biolink:NamedThing	negative regulation by host of symbiont catalytic activity	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by host of symbiont enzyme activity|down regulation by host of symbiont enzyme activity|downregulation by host of symbiont protein function|inhibition by host of symbiont protein function|downregulation by host of symbiont enzyme activity|down-regulation by host of symbiont protein function|inhibition by host of symbiont enzyme activity|inhibition of symbiont protein function|down-regulation by host of symbiont enzyme activity|inhibition of symbiont enzyme activity|negative regulation by host of symbiont molecular function|down regulation by host of symbiont protein function										GO:0052405			biological_process											owl:Class	
GO:0030714	biolink:NamedThing	anterior/posterior axis specification, follicular epithelium	Polarization of the follicle cells of an insect ovary along the anterior/posterior axis.	got7fsn_ti	anterior/posterior axis determination, follicular epithelium													biological_process											owl:Class	
GO:0050777	biolink:NamedThing	negative regulation of immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.	got7fsn_ti	down regulation of immune response|downregulation of immune response|inhibition of immune response|down-regulation of immune response													biological_process											owl:Class	
GO:0035877	biolink:NamedThing	death effector domain binding	Binding to a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD).	got7fsn_ti	DED binding				For binding to the death domain, consider instead the term 'death domain binding ; GO:0070513'.		bf	2011-05-31T09:40:46Z						molecular_function											owl:Class	
GO:0086009	biolink:NamedThing	membrane repolarization	The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.	got7fsn_ti							tb	2011-11-10T08:13:18Z						biological_process											owl:Class	
GO:0034220	biolink:NamedThing	ion transmembrane transport	A process in which an ion is transported across a membrane.	got7fsn_ti	ATP hydrolysis coupled ion transmembrane transport|transmembrane ion transport|ion membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.						GO:0099131			biological_process											owl:Class	
GO:0005048	biolink:NamedThing	signal sequence binding	Binding to a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized.	got7fsn_ti	signal sequence receptor|protein signal sequence binding|leader sequence binding										GO:0008249			molecular_function											owl:Class	
GO:0042277	biolink:NamedThing	peptide binding	Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds.	got7fsn_ti														molecular_function											owl:Class	
GO:0004402	biolink:NamedThing	histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.	got7fsn_ti	histone acetokinase activity|H4/H2 histone acetyltransferase activity|histone lysine acetyltransferase activity|nucleosome-histone acetyltransferase activity|histone transacetylase activity|acetyl-CoA:histone acetyltransferase activity|H2A/H2B histone acetyltransferase activity|H3/H4 histone acetyltransferase activity|H4/H2A acetyltransferase activity|histone acetylase activity				Note that the term 'histone lysine acetyltransferase activity ; GO:0046971' was merged into this term because only lysine residues are ever acetylated in histones, and so the term was redundant.						GO:0043166|GO:0046971|GO:0004403|GO:0004404|GO:0004406|GO:0004405	Reactome:R-HSA-3662335|MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-5144542|EC:2.3.1.48|Reactome:R-HSA-3697920|Reactome:R-HSA-3301345|Reactome:R-HSA-3301237|RHEA:21992|Reactome:R-HSA-3321975|Reactome:R-HSA-3321805|Reactome:R-HSA-3697008|Reactome:R-HSA-3662318|Reactome:R-HSA-3451147|Reactome:R-HSA-3318486|Reactome:R-HSA-5250938|Reactome:R-HSA-3318413|Reactome:R-HSA-3321883|Reactome:R-HSA-3318415		molecular_function											owl:Class	
GO:0010298	biolink:NamedThing	dihydrocamalexic acid decarboxylase activity	Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.	got7fsn_ti												RHEA:34807|MetaCyc:RXN-8275		molecular_function											owl:Class	
GO:0002947	biolink:NamedThing	tumor necrosis factor receptor superfamily complex	A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily.	got7fsn_ti	TNF receptor superfamily complex						hjd	2012-12-20T13:26:39Z						cellular_component											owl:Class	
GO:0009712	biolink:NamedThing	catechol-containing compound metabolic process	The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.	got7fsn_ti	catechol metabolism|catechol metabolic process													biological_process											owl:Class	
GO:0018958	biolink:NamedThing	phenol-containing compound metabolic process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.	got7fsn_ti	phenol-containing compound metabolism|hydroxybenzene metabolic process|carbolic acid metabolic process|carbolic acid metabolism|hydroxybenzene metabolism				Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds.							UM-BBD_pathwayID:phe		biological_process											owl:Class	
GO:0010688	biolink:NamedThing	negative regulation of ribosomal protein gene transcription by RNA polymerase II	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.	got7fsn_ti	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter													biological_process											owl:Class	
GO:0000122	biolink:NamedThing	negative regulation of transcription by RNA polymerase II	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter, global|inhibition of transcription from RNA polymerase II promoter|down regulation of transcription from RNA polymerase II promoter|downregulation of global transcription from RNA polymerase II promoter|negative regulation of gene-specific transcription from RNA polymerase II promoter|down-regulation of global transcription from RNA polymerase II promoter|down-regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from Pol II promoter|downregulation of transcription from RNA polymerase II promoter|inhibition of global transcription from RNA polymerase II promoter|negative regulation of global transcription from Pol II promoter|down regulation of global transcription from RNA polymerase II promoter										GO:0010553|GO:0045816			biological_process											owl:Class	
GO:0034218	biolink:NamedThing	ascospore wall chitin metabolic process	The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.	got7fsn_ti	ascospore wall chitin metabolism													biological_process											owl:Class	
GO:0071966	biolink:NamedThing	fungal-type cell wall polysaccharide metabolic process	The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall.	got7fsn_ti							mah	2010-10-14T11:56:47Z						biological_process											owl:Class	
GO:0008127	biolink:NamedThing	quercetin 2,3-dioxygenase activity	Catalysis of the reaction: H(+) + O(2) + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO.	got7fsn_ti	quercetin:oxygen 2,3-oxidoreductase (decyclizing)|flavonol 2,4-oxygenase activity|quercetinase activity											Reactome:R-HSA-8953398|RHEA:15381|MetaCyc:QUERCETIN-23-DIOXYGENASE-RXN|KEGG_REACTION:R02156|UM-BBD_reactionID:r0891|EC:1.13.11.24		molecular_function											owl:Class	
GO:0061820	biolink:NamedThing	telomeric D-loop disassembly	A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.	got7fsn_ti							dph							biological_process											owl:Class	
GO:0090657	biolink:NamedThing	telomeric loop disassembly	The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.	got7fsn_ti	t-loop disassembly|T loop disassembly						tb	2015-07-07T13:53:40Z						biological_process											owl:Class	
GO:0052697	biolink:NamedThing	xenobiotic glucuronidation	The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion.	got7fsn_ti	phase II metabolism						ai	2011-07-27T05:37:50Z						biological_process											owl:Class	
GO:0019371	biolink:NamedThing	cyclooxygenase pathway	The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.	got7fsn_ti														biological_process											owl:Class	
GO:0019369	biolink:NamedThing	arachidonic acid metabolic process	The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.	got7fsn_ti	arachidonic acid metabolism											Wikipedia:Arachidonic_acid		biological_process											owl:Class	
GO:0030959	biolink:NamedThing	peptide cross-linking via 3'-(3'-L-tyrosinyl)-L-tyrosine	The modification of two peptidyl-tyrosines to form a 3'-(3'-L-tyrosinyl)-L-tyrosine protein cross-link.	got7fsn_ti												RESID:AA0367		biological_process											owl:Class	
GO:0035560	biolink:NamedThing	pheophorbidase activity	Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a.	got7fsn_ti	PPD activity|pheophoridase activity|phedase activity						bf	2010-05-14T02:39:58Z				RHEA:32483|EC:3.1.1.82		molecular_function											owl:Class	
GO:0018250	biolink:NamedThing	peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine	The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG.	got7fsn_ti	peptidyl-dehydroalanine formation from peptidyl-tyrosine or peptidyl-serine|peptidyl-dehydroalanine anabolism from peptidyl-tyrosine or peptidyl-serine|peptidyl-dehydroalanine synthesis from peptidyl-tyrosine or peptidyl-serine											RESID:AA0181		biological_process											owl:Class	
GO:0018249	biolink:NamedThing	protein dehydration	The removal of a water group from a protein amino acid.	got7fsn_ti	protein amino acid dehydration													biological_process											owl:Class	
GO:0106260	biolink:NamedThing	DNA-DNA tethering activity	Bridging together two regions of a DNA molecule.	got7fsn_ti	dsDNA bridging|double-stranded DNA bridging	https://github.com/geneontology/go-ontology/issues/19385|https://github.com/geneontology/go-ontology/issues/20503					hjd	2020-05-07T19:53:35Z			GO:0140564			molecular_function											owl:Class	
GO:0050978	biolink:NamedThing	magnetoreception by sensory perception of electrical stimulus	The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish.	got7fsn_ti	magnetoreception through electrical stimulus|magnetoreception by electrical stimulus|magnetoreception, using electrical stimulus|magnetoreception, sensory perception of electrical stimulus													biological_process											owl:Class	
GO:0050958	biolink:NamedThing	magnetoreception	The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light.	got7fsn_ti	sensory perception of magnetic field|magnetoception											Wikipedia:Magnetoception		biological_process											owl:Class	
GO:0061726	biolink:NamedThing	mitochondrion disassembly	The disaggregation of a mitochondrion into its constituent components.	got7fsn_ti	mitochondrion degradation						dph	2015-07-08T13:59:16Z						biological_process											owl:Class	
GO:0043040	biolink:NamedThing	tRNA aminoacylation for nonribosomal peptide biosynthetic process	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis.	got7fsn_ti	tRNA aminoacylation for nonribosomal peptide synthesis|tRNA aminoacylation for nonribosomal peptide anabolism|tRNA aminoacylation for nonribosomal peptide biosynthesis|tRNA aminoacylation for nonribosomal peptide formation													biological_process											owl:Class	
GO:0043039	biolink:NamedThing	tRNA aminoacylation	The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid  group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.	got7fsn_ti	tRNA charging|aminoacyl-tRNA biosynthesis|aminoacyl-tRNA biosynthetic process													biological_process											owl:Class	
GO:1990450	biolink:NamedThing	linear polyubiquitin binding	Binding to a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next.	got7fsn_ti	M1-linked ubiquitin chain binding						bf	2014-08-06T11:10:26Z						molecular_function											owl:Class	
GO:0043130	biolink:NamedThing	ubiquitin binding	Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.	got7fsn_ti												Reactome:R-HSA-983152|Reactome:R-HSA-1169404|Reactome:R-HSA-205008		molecular_function											owl:Class	
GO:0090652	biolink:NamedThing	basolateral cytoplasm	The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells.	got7fsn_ti							tb	2015-07-01T15:46:19Z						cellular_component											owl:Class	
GO:0061176	biolink:NamedThing	type Ib terminal bouton	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.	got7fsn_ti	type Ib terminal button						dph	2010-07-13T09:20:04Z						cellular_component											owl:Class	
GO:0061174	biolink:NamedThing	type I terminal bouton	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.	got7fsn_ti	type I terminal button						dph	2010-07-13T09:13:05Z						cellular_component											owl:Class	
GO:0050151	biolink:NamedThing	oleate hydratase activity	Catalysis of the reaction: (R)-10-hydroxystearate = H(2)O + oleate.	got7fsn_ti	(R)-10-hydroxystearate 10-hydro-lyase activity|(R)-10-hydroxystearate 10-hydro-lyase (oleate-forming)											RHEA:21852|EC:4.2.1.53|KEGG_REACTION:R02813|MetaCyc:OLEATE-HYDRATASE-RXN		molecular_function											owl:Class	
GO:0061658	biolink:NamedThing	URM1 conjugating enzyme activity	Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y -> Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2						dph	2014-11-06T13:37:26Z						molecular_function											owl:Class	
GO:0062110	biolink:NamedThing	negative regulation of DNA recombinase disassembly	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components.	got7fsn_ti							dph	2019-02-05T13:57:35Z						biological_process											owl:Class	
GO:0009973	biolink:NamedThing	adenylyl-sulfate reductase activity	Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.	got7fsn_ti	AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)|adenosine phosphosulfate reductase activity|adenylyl-sulphate reductase activity|APS reductase activity|APS-reductase|AMP, sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)|adenosine 5'-phosphosulfate reductase											RHEA:24240|MetaCyc:ADENYLYLSULFATE-REDUCTASE-RXN|EC:1.8.99.2		molecular_function											owl:Class	
GO:0007450	biolink:NamedThing	dorsal/ventral pattern formation, imaginal disc	The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.	got7fsn_ti	dorsoventral pattern formation, imaginal disc|dorsal-ventral pattern formation, imaginal disc													biological_process											owl:Class	
GO:0007447	biolink:NamedThing	imaginal disc pattern formation	The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.	got7fsn_ti														biological_process											owl:Class	
GO:0043099	biolink:NamedThing	pyrimidine deoxyribonucleoside salvage	Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0046126	biolink:NamedThing	pyrimidine deoxyribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	pyrimidine deoxyribonucleoside formation|pyrimidine deoxyribonucleoside synthesis|pyrimidine deoxyribonucleoside biosynthesis|pyrimidine deoxyribonucleoside anabolism													biological_process											owl:Class	
GO:0060778	biolink:NamedThing	primary leaflet morphogenesis	The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis.	got7fsn_ti							dph	2009-07-25T07:15:48Z						biological_process											owl:Class	
GO:0060794	biolink:NamedThing	leaflet morphogenesis	The process in which the anatomical structures of the leaflet are generated and organized.	got7fsn_ti							dph	2009-08-04T02:58:14Z						biological_process											owl:Class	
GO:0051565	biolink:NamedThing	negative regulation of smooth endoplasmic reticulum calcium ion concentration	Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum.	got7fsn_ti	smooth ER calcium ion concentration reduction|reduction of calcium ion concentration in smooth endoplasmic reticulum|reduction of smooth endoplasmic reticulum calcium ion concentration|smooth endoplasmic reticulum calcium ion concentration reduction|reduction of smooth ER calcium ion concentration|reduction of calcium ion concentration in smooth ER													biological_process											owl:Class	
GO:0032471	biolink:NamedThing	negative regulation of endoplasmic reticulum calcium ion concentration	Any process that decreases the concentration of calcium ions in the endoplasmic reticulum.	got7fsn_ti	endoplasmic reticulum calcium ion concentration reduction|reduction of calcium ion concentration in ER|reduction of endoplasmic reticulum calcium ion concentration|reduction of calcium ion concentration in endoplasmic reticulum|reduction of ER calcium ion concentration|ER calcium ion concentration reduction													biological_process											owl:Class	
GO:0052542	biolink:NamedThing	defense response by callose deposition	Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	got7fsn_ti	callose localization during defense response|callose deposition during defense response													biological_process											owl:Class	
GO:0052545	biolink:NamedThing	callose localization	Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	got7fsn_ti	callose localisation													biological_process											owl:Class	
GO:0010399	biolink:NamedThing	rhamnogalacturonan I backbone metabolic process	The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone.	got7fsn_ti	rhamnogalacturonan I backbone metabolism													biological_process											owl:Class	
GO:0010395	biolink:NamedThing	rhamnogalacturonan I metabolic process	The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone.	got7fsn_ti	rhamnogalacturonan I metabolism|RGI metabolism													biological_process											owl:Class	
GO:0008881	biolink:NamedThing	glutamate racemase activity	Catalysis of the reaction: L-glutamate = D-glutamate.	got7fsn_ti												KEGG_REACTION:R00260|RHEA:12813|EC:5.1.1.3|MetaCyc:GLUTRACE-RXN		molecular_function											owl:Class	
GO:0047661	biolink:NamedThing	amino-acid racemase activity	Catalysis of the reaction: an L-amino acid = a D-amino acid.	got7fsn_ti	L-amino acid racemase activity											MetaCyc:AMINO-ACID-RACEMASE-RXN|RHEA:18317|EC:5.1.1.10		molecular_function											owl:Class	
GO:0010262	biolink:NamedThing	somatic embryogenesis	Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes.	got7fsn_ti														biological_process											owl:Class	
GO:0009793	biolink:NamedThing	embryo development ending in seed dormancy	The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	embryogenesis													biological_process											owl:Class	
GO:0031533	biolink:NamedThing	mRNA cap methyltransferase complex	A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.	got7fsn_ti	mRNA (guanine-N7) methyltransferase complex|mRNA capping enzyme complex													cellular_component											owl:Class	
GO:0033927	biolink:NamedThing	glucan 1,4-alpha-maltohexaosidase activity	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.	got7fsn_ti	G6-amylase activity|maltohexaose-producing amylase activity|exo-maltohexaohydrolase activity|1,4-alpha-D-glucan maltohexaohydrolase activity											MetaCyc:3.2.1.98-RXN|EC:3.2.1.98		molecular_function											owl:Class	
GO:0004733	biolink:NamedThing	pyridoxamine-phosphate oxidase activity	Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide.	got7fsn_ti	pyridoxamine 5'-phosphate oxidase activity|pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)|pyridoxine (pyridoxamine)phosphate oxidase activity|pyridoxaminephosphate oxidase deaminating|pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating)|pyridoxine (pyridoxamine) 5'-phosphate oxidase activity|PMP oxidase activity|pyridoxal 5'-phosphate synthase activity|PdxH|pyridoxamine phosphate oxidase activity											Reactome:R-HSA-965079|EC:1.4.3.5|MetaCyc:PMPOXI-RXN|Reactome:R-HSA-965019|RHEA:15817		molecular_function											owl:Class	
GO:0030029	biolink:NamedThing	actin filament-based process	Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.	got7fsn_ti	microfilament-based process													biological_process											owl:Class	
GO:0035497	biolink:NamedThing	cAMP response element binding	Binding to a cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.	got7fsn_ti	cyclic-AMP-responsive element binding|cyclic-AMP response element binding|cyclic AMP response element binding|CRE binding|cAMP-responsive element binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		bf	2010-04-29T09:26:47Z						molecular_function											owl:Class	
GO:0000978	biolink:NamedThing	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.	got7fsn_ti	RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II proximal promoter sequence-specific DNA binding|RNA polymerase II promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding				Note that the phrase "upstream activating sequence", or UAS is often used in S. cerevisiae literature to refer to cis-regulatory sequences. In bacteria such as E. coli, the phrase "upstream activating sequence", or UAS is usually a synonym for "enhancer".		krc	2010-08-10T02:17:19Z			GO:0000980			molecular_function											owl:Class	
GO:0016068	biolink:NamedThing	type I hypersensitivity	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.	got7fsn_ti	immediate hypersensitivity response				Note that localized and systemic anaphylaxis is usually a result of type I hypersensitivity.							Wikipedia:Type_I_hypersensitivity		biological_process											owl:Class	
GO:0002524	biolink:NamedThing	hypersensitivity	An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.	got7fsn_ti	hypersensitivity response											Wikipedia:Hypersensitivity		biological_process											owl:Class	
GO:0009855	biolink:NamedThing	determination of bilateral symmetry	The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.	got7fsn_ti	determination of bilateral asymmetry													biological_process											owl:Class	
GO:0102319	biolink:NamedThing	2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity	Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine <=> H+ + 2'-N-acetylparomamine(2+) + UDP(3-).	got7fsn_ti												MetaCyc:RXN-13122|RHEA:33947|EC:2.4.1.283		molecular_function											owl:Class	
GO:0030522	biolink:NamedThing	intracellular receptor signaling pathway	Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.	got7fsn_ti	intracellular receptor mediated signaling pathway|intracellular receptor-mediated signalling pathway|intracellular receptor-mediated signaling pathway													biological_process											owl:Class	
GO:0046019	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter by pheromones	Any process involving pheromones that modulates the frequency, rate or extent or transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of transcription from Pol II promoter by pheromones													biological_process											owl:Class	
GO:0021694	biolink:NamedThing	cerebellar Purkinje cell layer formation	The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	got7fsn_ti														biological_process											owl:Class	
GO:0052702	biolink:NamedThing	cellular modified histidine catabolic process	The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	got7fsn_ti	cellular histidine derivative degradation|cellular modified histidine degradation|modified histidine catabolic process|cellular modified histidine catabolism|cellular histidine derivative catabolism|histidine derivative catabolic process|cellular histidine derivative breakdown|cellular modified histidine breakdown|modified histidine catabolism|cellular histidine derivative catabolic process						ai	2011-08-01T03:48:41Z						biological_process											owl:Class	
GO:0120311	biolink:NamedThing	ciliary pro-basal body maturation	A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium.	got7fsn_ti	flagellar probasal body maturation|flagellar pro-basal body maturation|pro-basal body maturation						krc	2021-03-26T17:41:59Z						biological_process											owl:Class	
GO:0044782	biolink:NamedThing	cilium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.	got7fsn_ti	microtubule-based flagellum organization				Note that we deem cilium and microtubule-based flagellum to be equivalent.		jl	2013-03-27T15:09:58Z						biological_process											owl:Class	
GO:0048809	biolink:NamedThing	analia morphogenesis	The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0010759	biolink:NamedThing	positive regulation of macrophage chemotaxis	Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0071675	biolink:NamedThing	regulation of mononuclear cell migration	Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.	got7fsn_ti							mah	2010-02-16T02:11:53Z						biological_process											owl:Class	
GO:0005856	biolink:NamedThing	cytoskeleton	Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.	got7fsn_ti												Wikipedia:Cytoskeleton		cellular_component											owl:Class	
GO:0000034	biolink:NamedThing	adenine deaminase activity	Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.	got7fsn_ti	ADase activity|adenine aminohydrolase activity|adenine aminase activity|adenase activity											RHEA:23688|EC:3.5.4.2|MetaCyc:ADENINE-DEAMINASE-RXN		molecular_function											owl:Class	
GO:0044363	biolink:NamedThing	modulation of potassium channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism.	got7fsn_ti							jl	2011-10-27T02:19:32Z						biological_process											owl:Class	
GO:0044561	biolink:NamedThing	modulation of ion channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism.	got7fsn_ti	regulation of ion channel activity in other organism						jl	2012-04-05T03:48:28Z						biological_process											owl:Class	
GO:0048333	biolink:NamedThing	mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.	got7fsn_ti	mesoderm cell differentiation													biological_process											owl:Class	
GO:0032488	biolink:NamedThing	Cdc42 protein signal transduction	A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.	got7fsn_ti	Cdc42 signaling pathway|cdc42 signalling pathway|Cdc42 signaling													biological_process											owl:Class	
GO:0007266	biolink:NamedThing	Rho protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.	got7fsn_ti	Rho mediated signal transduction													biological_process											owl:Class	
GO:1990154	biolink:NamedThing	enzyme IIA-maltose transporter complex	A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter.	got7fsn_ti	maltose transporter inhibitor complex|EIIA(Glc)-maltose transporter complex|EIIA(Glc)-MalFGK2 complex						bhm	2013-08-01T09:27:25Z						cellular_component											owl:Class	
GO:0009407	biolink:NamedThing	toxin catabolic process	The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.	got7fsn_ti	toxin breakdown|toxin degradation|toxin catabolism													biological_process											owl:Class	
GO:0030098	biolink:NamedThing	lymphocyte differentiation	The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.	got7fsn_ti	lymphocyte cell differentiation|lymphocytic blood cell differentiation|lymphocyte development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.						GO:0046650			biological_process											owl:Class	
GO:0046649	biolink:NamedThing	lymphocyte activation	A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti														biological_process											owl:Class	
GO:0061102	biolink:NamedThing	stomach neuroendocrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.	got7fsn_ti	gastric neuroendocrine cell differentiation						dph	2010-04-28T09:47:07Z						biological_process											owl:Class	
GO:0036258	biolink:NamedThing	multivesicular body assembly	The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.	got7fsn_ti	MVB formation|multivesicular body biogenesis|MVB biogenesis						bf	2012-06-15T01:12:24Z						biological_process											owl:Class	
GO:0045259	biolink:NamedThing	proton-transporting ATP synthase complex	A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient.	got7fsn_ti	F1-F0 complex|proton-transporting F-type ATPase complex|hydrogen-transporting ATP synthase complex|hydrogen-translocating F-type ATPase complex										GO:0045255			cellular_component											owl:Class	
GO:0048498	biolink:NamedThing	establishment of petal orientation	The process that determines the orientation of petals with reference to the central axis.	got7fsn_ti														biological_process											owl:Class	
GO:0045990	biolink:NamedThing	carbon catabolite regulation of transcription	A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.	got7fsn_ti	regulation of transcription by carbon catabolites													biological_process											owl:Class	
GO:0032420	biolink:NamedThing	stereocilium	An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.	got7fsn_ti														cellular_component											owl:Class	
GO:0043957	biolink:NamedThing	acryloyl-CoA reductase (NADP+) activity	Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+.	got7fsn_ti	acetyl-coenzyme A synthetase|AMP-dependent synthetase and ligase|enoyl-CoA hydratase/isomerase|acryloyl-CoA reductase (NADPH) activity|AMP-dependent synthetase and ligase:enoyl-CoA hydratase/isomerase|acrylyl-CoA reductase (NADPH) activity|acetyl-coenzyme A synthetase/GroES-like domain				Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.							EC:1.3.1.84|KEGG_REACTION:R00919|RHEA:26454|MetaCyc:RXN-9087		molecular_function											owl:Class	
GO:0006530	biolink:NamedThing	asparagine catabolic process	The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid.	got7fsn_ti	asparagine breakdown|asparagine degradation|asparagine catabolism													biological_process											owl:Class	
GO:0009065	biolink:NamedThing	glutamine family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.	got7fsn_ti	glutamine family amino acid degradation|glutamine family amino acid catabolism|glutamine family amino acid breakdown													biological_process											owl:Class	
GO:0004099	biolink:NamedThing	chitin deacetylase activity	Catalysis of the reaction: chitin + H2O = chitosan + acetate.	got7fsn_ti	chitin amidohydrolase activity											MetaCyc:CHITIN-DEACETYLASE-RXN|RHEA:10464|EC:3.5.1.41		molecular_function											owl:Class	
GO:0009995	biolink:NamedThing	soluble molecule recognition	The recognition of soluble molecules in the environment.	got7fsn_ti														biological_process											owl:Class	
GO:1990124	biolink:NamedThing	messenger ribonucleoprotein complex	A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules.	got7fsn_ti	mRNA-protein complex|mRNP|messenger ribonucleoprotein particle|mRNP complex						bf	2013-06-13T09:20:52Z						cellular_component											owl:Class	
GO:0015293	biolink:NamedThing	symporter activity	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	got7fsn_ti	symport|porter activity|cotransporter activity													molecular_function											owl:Class	
GO:0050820	biolink:NamedThing	positive regulation of coagulation	Any process that activates or increases the frequency, rate or extent of coagulation.	got7fsn_ti	up-regulation of coagulation|activation of coagulation|upregulation of coagulation|up regulation of coagulation|positive regulation of clotting|stimulation of coagulation													biological_process											owl:Class	
GO:1903429	biolink:NamedThing	regulation of cell maturation	Any process that modulates the frequency, rate or extent of cell maturation.	got7fsn_ti	regulation of functional differentiation						jl	2014-09-15T13:31:23Z						biological_process											owl:Class	
GO:0060284	biolink:NamedThing	regulation of cell development	Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0018386	biolink:NamedThing	N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine	The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine.	got7fsn_ti												RESID:AA0274		biological_process											owl:Class	
GO:0031365	biolink:NamedThing	N-terminal protein amino acid modification	The alteration of the N-terminal amino acid residue in a protein.	got7fsn_ti	peptide or protein amino-terminal blocking|peptide/protein amino-terminal blocking										GO:0018409			biological_process											owl:Class	
GO:0051249	biolink:NamedThing	regulation of lymphocyte activation	Any process that modulates the frequency, rate or extent of lymphocyte activation.	got7fsn_ti														biological_process											owl:Class	
GO:0045858	biolink:NamedThing	positive regulation of molecular function, epigenetic	Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.	got7fsn_ti	up-regulation of protein activity, epigenetic|stimulation of protein activity, epigenetic|activation of protein activity, epigenetic|up regulation of protein activity, epigenetic|positive regulation of protein activity, epigenetic|upregulation of protein activity, epigenetic													biological_process											owl:Class	
GO:0044093	biolink:NamedThing	positive regulation of molecular function	Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.	got7fsn_ti							jl	2009-04-21T04:11:06Z						biological_process											owl:Class	
GO:0004341	biolink:NamedThing	gluconolactonase activity	Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate.	got7fsn_ti	lactonase activity|D-glucono-1,5-lactone lactonohydrolase activity|gulonolactonase activity|aldonolactonase activity|glucono-delta-lactonase activity											EC:3.1.1.17|RHEA:10440|MetaCyc:GLUCONOLACT-RXN		molecular_function											owl:Class	
GO:0016851	biolink:NamedThing	magnesium chelatase activity	Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate.	got7fsn_ti	magnesium-protoporphyrin chelatase activity|protoporphyrin IX magnesium-chelatase activity|Mg-protoporphyrin IX magnesio-lyase activity|Mg-protoporphyrin IX magnesium-lyase activity|magnesium-protoporphyrin IX chelatase activity|protoporphyrin IX Mg-chelatase activity|Mg-protoporphyrin IX chelatase activity|Mg-chelatase activity|magnesium-chelatase activity				Note that this was EC:4.99.1.1.							MetaCyc:RXN1F-20|KEGG_REACTION:R03877|RHEA:13961|EC:6.6.1.1		molecular_function											owl:Class	
GO:0051003	biolink:NamedThing	ligase activity, forming nitrogen-metal bonds, forming coordination complexes	Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex.	got7fsn_ti												EC:6.6.1.-		molecular_function											owl:Class	
GO:0045987	biolink:NamedThing	positive regulation of smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.	got7fsn_ti	upregulation of smooth muscle contraction|stimulation of smooth muscle contraction|activation of smooth muscle contraction|up regulation of smooth muscle contraction|up-regulation of smooth muscle contraction													biological_process											owl:Class	
GO:0045933	biolink:NamedThing	positive regulation of muscle contraction	Any process that activates or increases the frequency, rate or extent of muscle contraction.	got7fsn_ti	activation of muscle contraction|up-regulation of muscle contraction|upregulation of muscle contraction|stimulation of muscle contraction|up regulation of muscle contraction													biological_process											owl:Class	
GO:0047075	biolink:NamedThing	2,5-dihydroxypyridine 5,6-dioxygenase activity	Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate.	got7fsn_ti	pyridine-2,5-diol dioxygenase activity|2,5-dihydroxypyridine oxygenase activity|2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase activity											UM-BBD_reactionID:r1443|MetaCyc:1.13.11.9-RXN|RHEA:27522|EC:1.13.11.9		molecular_function											owl:Class	
GO:0002417	biolink:NamedThing	B cell antigen processing and presentation mediated by B cell receptor uptake of antigen	B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor.	got7fsn_ti	B-cell antigen processing and presentation mediated by B cell receptor uptake of antigen|B-lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen|B lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen													biological_process											owl:Class	
GO:0018094	biolink:NamedThing	protein polyglycylation	The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid.	got7fsn_ti												RESID:AA0201		biological_process											owl:Class	
GO:0030634	biolink:NamedThing	carbon fixation by acetyl-CoA pathway	A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2).	got7fsn_ti	acetyl CoA pathway|Ljungdahl-Wood pathway|reductive acetyl CoA pathway											MetaCyc:CODH-PWY|Wikipedia:Wood-Ljungdahl_pathway		biological_process											owl:Class	
GO:0006085	biolink:NamedThing	acetyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.	got7fsn_ti	acetyl-CoA anabolism|acetyl-CoA biosynthesis|acetyl-CoA formation|acetyl-CoA synthesis											MetaCyc:PWY-5173		biological_process											owl:Class	
GO:0060639	biolink:NamedThing	positive regulation of salivary gland formation by mesenchymal-epithelial signaling	Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.	got7fsn_ti	positive regulation of salivary gland formation by mesenchymal-epithelial signalling						dph	2009-05-20T04:26:43Z						biological_process											owl:Class	
GO:0035795	biolink:NamedThing	negative regulation of mitochondrial membrane permeability	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.	got7fsn_ti	negative regulation of transport across mitochondrial membrane|mitochondrial membrane impermeabilization|mitochondrial membrane impermeability						bf	2011-04-11T01:45:26Z						biological_process											owl:Class	
GO:1905709	biolink:NamedThing	negative regulation of membrane permeability	Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane.	got7fsn_ti							hbye	2016-11-18T13:10:42Z						biological_process											owl:Class	
GO:0090606	biolink:NamedThing	single-species surface biofilm formation	A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.	got7fsn_ti	multicellular pellicle formation						tb	2014-09-16T14:47:11Z			GO:0032022			biological_process											owl:Class	
GO:0090604	biolink:NamedThing	surface biofilm formation	A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	got7fsn_ti							tb	2014-09-16T14:38:45Z						biological_process											owl:Class	
GO:0001553	biolink:NamedThing	luteinization	The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.	got7fsn_ti	luteal phase											Wikipedia:Luteal_phase|Wikipedia:Luteinization		biological_process											owl:Class	
GO:0033915	biolink:NamedThing	mannan 1,2-(1,3)-alpha-mannosidase activity	Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.	got7fsn_ti	1,2-1,3-alpha-D-mannan mannohydrolase activity|exo-1,2-1,3-alpha-mannosidase activity											EC:3.2.1.77|MetaCyc:3.2.1.77-RXN		molecular_function											owl:Class	
GO:0004559	biolink:NamedThing	alpha-mannosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.	got7fsn_ti	alpha-D-mannoside mannohydrolase activity|1,2-alpha-D-mannosidase activity|1,2-alpha-mannosidase|p-nitrophenyl-alpha-mannosidase activity|alpha-D-mannopyranosidase activity|alpha-D-mannosidase activity|exo-alpha-mannosidase activity											Reactome:R-HSA-6799545|EC:3.2.1.24|Reactome:R-HSA-9694656|Reactome:R-HSA-8853686|MetaCyc:3.2.1.24-RXN		molecular_function											owl:Class	
GO:0060066	biolink:NamedThing	oviduct development	The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.	got7fsn_ti	Mullerian tract development|fallopian tube development													biological_process											owl:Class	
GO:0072310	biolink:NamedThing	glomerular epithelial cell development	The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.	got7fsn_ti							mah	2010-04-09T06:47:31Z						biological_process											owl:Class	
GO:0070482	biolink:NamedThing	response to oxygen levels	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.	got7fsn_ti														biological_process											owl:Class	
GO:0003860	biolink:NamedThing	3-hydroxyisobutyryl-CoA hydrolase activity	Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.	got7fsn_ti	HIB CoA deacylase activity|3-hydroxy-isobutyryl CoA hydrolase activity|3-hydroxy-2-methylpropanoyl-CoA hydrolase activity											MetaCyc:3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN|EC:3.1.2.4|Reactome:R-HSA-70881|RHEA:20888		molecular_function											owl:Class	
GO:0004760	biolink:NamedThing	serine-pyruvate transaminase activity	Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.	got7fsn_ti	L-serine:pyruvate aminotransferase activity|hydroxypyruvate:L-alanine transaminase activity|serine-pyruvate aminotransferase, type 2A|serine-pyruvate aminotransferase, type 1|serine-pyruvate aminotransferase, type 2B|serine-pyruvate aminotransferase activity|serine--pyruvate aminotransferase activity|SPT										GO:0004761|GO:0004763|GO:0004762	MetaCyc:SERINE--PYRUVATE-AMINOTRANSFERASE-RXN|RHEA:22852|KEGG_REACTION:R00585|EC:2.6.1.51		molecular_function											owl:Class	
GO:0010371	biolink:NamedThing	regulation of gibberellin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.	got7fsn_ti	regulation of gibberellic acid biosynthetic process													biological_process											owl:Class	
GO:0052205	biolink:NamedThing	modulation of molecular function in other organism involved in symbiotic interaction	The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation of molecular function in other organism during symbiotic interaction|modification of protein function in other organism during symbiotic interaction|modification of molecular function in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0061220	biolink:NamedThing	mesonephric macula densa development	The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.	got7fsn_ti							dph	2010-08-19T01:11:41Z						biological_process											owl:Class	
GO:0072024	biolink:NamedThing	macula densa development	The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.	got7fsn_ti							mah	2010-01-25T02:40:15Z						biological_process											owl:Class	
GO:0051430	biolink:NamedThing	corticotropin-releasing hormone receptor 1 binding	Binding to a corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.	got7fsn_ti	CRHR1 binding|type 1 corticotropin releasing factor receptor binding|type 1 corticotropin releasing factor receptor ligand|type 1 corticotropin-releasing factor receptor binding										GO:0031743			molecular_function											owl:Class	
GO:0051429	biolink:NamedThing	corticotropin-releasing hormone receptor binding	Binding to a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.	got7fsn_ti	corticotropin-releasing factor receptor binding|CRH receptor binding|CRF receptor binding|corticotropin releasing factor receptor ligand|corticotropin releasing factor receptor binding|CRHR binding										GO:0031742			molecular_function											owl:Class	
GO:0008817	biolink:NamedThing	cob(I)yrinic acid a,c-diamide adenosyltransferase activity	Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin.	got7fsn_ti	ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity|vitamin B12s adenosyltransferase activity|aquocob(I)alamin vitamin B12s adenosyltransferase activity|ATP:corrinoid adenosyltransferase activity|cob(I)alamin adenosyltransferase activity|CobA|aquacob(I)alamin adenosyltransferase activity|ATP:cob(I)alamin Co-beta-adenosyltransferase activity|ATP:cob(I)alamin cobeta-adenosyltransferase activity											EC:2.5.1.17|Reactome:R-HSA-3159253|RHEA:14725|MetaCyc:COBALADENOSYLTRANS-RXN|Reactome:R-HSA-3322125		molecular_function											owl:Class	
GO:1990932	biolink:NamedThing	5.8S rRNA binding	Binding to 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA.	got7fsn_ti							sl	2016-03-14T20:25:41Z						molecular_function											owl:Class	
GO:0031154	biolink:NamedThing	culmination involved in sorocarp development	The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.	got7fsn_ti	culmination during sorocarp development|culmination during fruiting body development|culminant development													biological_process											owl:Class	
GO:0042972	biolink:NamedThing	licheninase activity	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds.	got7fsn_ti	1,3;1,4-beta-glucan 4-glucanohydrolase activity|1,3-1,4-beta-D-glucan 4-glucanohydrolase activity|1,3;1,4-beta-glucan endohydrolase activity|beta-(1->3), (1->4)-D-glucan 4-glucanohydrolase activity|lichenase activity|mixed linkage beta-glucanase activity|1,3-1,4-beta-glucan 4-glucanohydrolase activity|beta-glucanase activity|endo-beta-1,3-1,4 glucanase activity											EC:3.2.1.73|MetaCyc:3.2.1.73-RXN		molecular_function											owl:Class	
GO:0010390	biolink:NamedThing	histone monoubiquitination	The modification of histones by addition of a single ubiquitin group.	got7fsn_ti														biological_process											owl:Class	
GO:0016267	biolink:NamedThing	O-glycan processing, core 1	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.	got7fsn_ti														biological_process											owl:Class	
GO:0016266	biolink:NamedThing	O-glycan processing	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure.	got7fsn_ti														biological_process											owl:Class	
GO:0005092	biolink:NamedThing	GDP-dissociation inhibitor activity	Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.	got7fsn_ti	GDI													molecular_function											owl:Class	
GO:0030695	biolink:NamedThing	GTPase regulator activity	Binds to and modulates the activity of a GTPase.	got7fsn_ti	small GTPase regulator activity|small GTPase regulatory/interacting protein activity										GO:0005083			molecular_function											owl:Class	
GO:0030757	biolink:NamedThing	3-methylquercitin 7-O-methyltransferase activity	Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine.	got7fsn_ti	flavonol 7-methyltransferase activity|S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity|7-OMT activity|3-methylquercetin 7-O-methyltransferase activity|flavonol 7-O-methyltransferase activity|S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity											EC:2.1.1.82|KEGG_REACTION:R05323|MetaCyc:2.1.1.82-RXN|RHEA:16181		molecular_function											owl:Class	
GO:0044837	biolink:NamedThing	actomyosin contractile ring organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring.	got7fsn_ti	cytokinesis, actomyosin contractile ring organization						jl	2014-02-26T15:31:31Z						biological_process											owl:Class	
GO:0031032	biolink:NamedThing	actomyosin structure organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.	got7fsn_ti	actomyosin organization|actomyosin structure organisation|actomyosin structure organization and biogenesis				Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins.									biological_process											owl:Class	
GO:0097038	biolink:NamedThing	perinuclear endoplasmic reticulum	The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes.	got7fsn_ti	perinuclear ER						pr	2011-04-12T10:51:05Z						cellular_component											owl:Class	
GO:0005291	biolink:NamedThing	high-affinity L-histidine transmembrane transporter activity	Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity histidine permease activity|high affinity L-histidine transmembrane transporter activity													molecular_function											owl:Class	
GO:0006277	biolink:NamedThing	DNA amplification	The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment.	got7fsn_ti														biological_process											owl:Class	
GO:0018566	biolink:NamedThing	1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate.	got7fsn_ti	1,2-dihydroxynaphthalene-6-sulphonate 1,8a-dioxygenase activity											UM-BBD_reactionID:r0324|EC:1.13.11.-		molecular_function											owl:Class	
GO:0019878	biolink:NamedThing	lysine biosynthetic process via aminoadipic acid	The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.	got7fsn_ti	lysine biosynthetic process, aminoadipic acid pathway|lysine biosynthetic process, aminoadipic pathway|lysine biosynthesis, aminoadipic acid pathway|lysine synthesis via aminoadipic acid|lysine anabolism via aminoadipic acid|lysine formation via aminoadipic acid|lysine biosynthesis, aminoadipic pathway													biological_process											owl:Class	
GO:0009085	biolink:NamedThing	lysine biosynthetic process	The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.	got7fsn_ti	lysine biosynthesis|lysine synthesis|lysine formation|lysine anabolism											MetaCyc:PWY-5097		biological_process											owl:Class	
GO:0097682	biolink:NamedThing	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity	Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.	got7fsn_ti							pr	2014-12-17T16:50:30Z						molecular_function											owl:Class	
GO:0005217	biolink:NamedThing	intracellular ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0009852	biolink:NamedThing	auxin catabolic process	The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth.	got7fsn_ti	auxin breakdown|auxin degradation|auxin catabolism													biological_process											owl:Class	
GO:0036026	biolink:NamedThing	protein C inhibitor-PLAT complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator.	got7fsn_ti	SERPINA5-PLAT complex|protein C inhibitor-tPA complex|serpin A5-PLAT complex|protein C inhibitor-tissue-type plasminogen activator complex|plasma serine protease inhibitor-PLAT complex|PCI-PLAT complex						bf	2011-10-19T01:30:56Z						cellular_component											owl:Class	
GO:0042474	biolink:NamedThing	middle ear morphogenesis	The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).	got7fsn_ti														biological_process											owl:Class	
GO:0044227	biolink:NamedThing	methane-oxidizing organelle	A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms.	got7fsn_ti	methane-oxidizing compartment|methanotroph intracytoplasmic membrane-bound compartment						jl	2009-11-17T02:13:52Z						cellular_component											owl:Class	
GO:0061864	biolink:NamedThing	basement membrane constituent secretion	The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell.	got7fsn_ti							dph	2017-04-07T18:23:39Z						biological_process											owl:Class	
GO:0070278	biolink:NamedThing	extracellular matrix constituent secretion	The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.	got7fsn_ti	ECM secretion|ECM constituent secretion													biological_process											owl:Class	
GO:0140444	biolink:NamedThing	cytoskeleton-nuclear membrane anchor activity	The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane.	got7fsn_ti	nuclear membrane-cytoskeleton anchor activity|cytoskeleton nuclear membrane anchor activity|cytoskeletal protein-nuclear membrane adaptor activity|cytoskeletal protein-nuclear membrane anchor activity	https://github.com/geneontology/go-ontology/issues/18283					pg	2020-03-24T14:57:59Z						molecular_function											owl:Class	
GO:0043495	biolink:NamedThing	protein-membrane adaptor activity	The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.	got7fsn_ti	anchoring|protein membrane adaptor|protein membrane anchor|protein membrane adaptor activity	https://github.com/geneontology/go-ontology/issues/19090												molecular_function											owl:Class	
GO:0018221	biolink:NamedThing	peptidyl-serine palmitoylation	The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine.	got7fsn_ti	peptidyl-serine O-palmitoylation				Palmitoylation of a non-terminal serine residue always occurs on an oxygen (O) atom.							RESID:AA0080		biological_process											owl:Class	
GO:0044826	biolink:NamedThing	viral genome integration into host DNA	The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.	got7fsn_ti	viral genome integration						jl	2014-02-04T16:58:43Z						biological_process											owl:Class	
GO:0090461	biolink:NamedThing	glutamate homeostasis	Any process involved in the maintenance of an internal steady state of glutamate within an organism or cell.	got7fsn_ti							tb	2012-09-24T14:22:02Z						biological_process											owl:Class	
GO:0097269	biolink:NamedThing	all-trans-decaprenyl-diphosphate synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate.	got7fsn_ti	(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity|2-trans,6-trans-farnesyl diphosphate activity						pr	2012-03-20T01:00:23Z				RHEA:27802|Reactome:R-HSA-2162253|EC:2.5.1.91		molecular_function											owl:Class	
GO:0047396	biolink:NamedThing	glycosylphosphatidylinositol diacylglycerol-lyase activity	Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate.	got7fsn_ti	GPI-PLC activity|GPI-specific phospholipase C activity|glycosylphosphatidylinositol-specific phospholipase C activity|6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming) activity|variant-surface-glycoprotein phospholipase C activity|VSG-lipase activity|6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase [6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate-forming]|glycosylphosphatidylinositol-phospholipase C activity|glycosyl inositol phospholipid anchor-hydrolyzing enzyme activity|(glycosyl)phosphatidylinositol-specific phospholipase C activity											MetaCyc:3.1.4.47-RXN|RHEA:14333|EC:4.6.1.14		molecular_function											owl:Class	
GO:0016849	biolink:NamedThing	phosphorus-oxygen lyase activity	Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.	got7fsn_ti												EC:4.6.-.-		molecular_function											owl:Class	
GO:0071046	biolink:NamedThing	nuclear polyadenylation-dependent ncRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.	got7fsn_ti	nuclear poly(A)-dependent ncRNA catabolic process						krc	2009-08-06T02:14:53Z						biological_process											owl:Class	
GO:0102831	biolink:NamedThing	stachyose synthase activity	Catalysis of the reaction: 2 raffinose <=> stachyose + sucrose.	got7fsn_ti												MetaCyc:RXN-8287		molecular_function											owl:Class	
GO:0150002	biolink:NamedThing	distal dendrite	The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma).	got7fsn_ti														cellular_component											owl:Class	
GO:0030425	biolink:NamedThing	dendrite	A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.	got7fsn_ti												NIF_Subcellular:sao1211023249|Wikipedia:Dendrite		cellular_component											owl:Class	
GO:0031320	biolink:NamedThing	hexitol dehydrogenase activity	Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0007018	biolink:NamedThing	microtubule-based movement	A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components.  Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.	got7fsn_ti														biological_process											owl:Class	
GO:0042701	biolink:NamedThing	progesterone secretion	The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.	got7fsn_ti														biological_process											owl:Class	
GO:0046253	biolink:NamedThing	anaerobic toluene biosynthetic process	The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.	got7fsn_ti	anaerobic toluene formation|anaerobic toluene synthesis|anaerobic toluene anabolism|anaerobic toluene biosynthesis				This term was reinstated from obsolete.									biological_process											owl:Class	
GO:0018971	biolink:NamedThing	anaerobic toluene metabolic process	The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen.	got7fsn_ti	anaerobic toluene metabolism											UM-BBD_pathwayID:tol2		biological_process											owl:Class	
GO:0030981	biolink:NamedThing	cortical microtubule cytoskeleton	The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0030863	biolink:NamedThing	cortical cytoskeleton	The portion of the cytoskeleton that lies just beneath the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0044540	biolink:NamedThing	L-cystine L-cysteine-lyase (deaminating)	Catalysis of the reaction: L-cystine + H2O <=> pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide.	got7fsn_ti							jl	2012-03-22T11:33:32Z				KEGG_REACTION:R02408|RHEA:24927|EC:4.4.1.1		molecular_function											owl:Class	
GO:0032584	biolink:NamedThing	growth cone membrane	The portion of the plasma membrane surrounding a growth cone.	got7fsn_ti														cellular_component											owl:Class	
GO:0097215	biolink:NamedThing	negative regulation of lysosomal membrane permeability	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.	got7fsn_ti	negative regulation of lysosome membrane permeability						pr	2012-01-12T10:23:42Z						biological_process											owl:Class	
GO:0097213	biolink:NamedThing	regulation of lysosomal membrane permeability	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.	got7fsn_ti	regulation of lysosome membrane permeability						pr	2012-01-12T10:19:44Z						biological_process											owl:Class	
GO:0016085	biolink:NamedThing	myoinhibitory hormone activity	The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction.	got7fsn_ti														molecular_function											owl:Class	
GO:0005179	biolink:NamedThing	hormone activity	The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.	got7fsn_ti	cAMP generating peptide activity|lipopeptide hormone|peptide hormone|glycopeptide hormone				Also consider annotating to 'receptor agonist activity ; GO:0048018'.									molecular_function											owl:Class	
GO:0009885	biolink:NamedThing	transmembrane histidine kinase cytokinin receptor activity	Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0009884	biolink:NamedThing	cytokinin receptor activity	Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0008906	biolink:NamedThing	inosine kinase activity	Catalysis of the reaction: ATP + inosine = ADP + IMP.	got7fsn_ti	ATP:inosine 5'-phosphotransferase activity|inosine kinase (phosphorylating)|inosine-guanosine kinase activity											RHEA:21140|EC:2.7.1.73|MetaCyc:INOSINEKIN-RXN		molecular_function											owl:Class	
GO:1990330	biolink:NamedThing	IscS-IscU complex	A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consisting of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group.	got7fsn_ti							bhm	2014-03-17T10:08:19Z						cellular_component											owl:Class	
GO:1990228	biolink:NamedThing	sulfurtransferase complex	A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor).	got7fsn_ti	sulfur transfer complex|SufE complex|ThiF-ThiS complex|SufE dimer						bhm	2013-11-12T09:08:23Z						cellular_component											owl:Class	
GO:0005753	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex	A proton-transporting ATP synthase complex found in the mitochondrial membrane.	got7fsn_ti	mitochondrial respiratory chain complex V										GO:0016470			cellular_component											owl:Class	
GO:0009848	biolink:NamedThing	indoleacetic acid biosynthetic process via tryptophan	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan.	got7fsn_ti	indoleacetic acid synthesis via tryptophan|indoleacetic acid formation via tryptophan|indoleacetic acid anabolism via tryptophan|IAA biosynthetic process via tryptophan											MetaCyc:PWY-581		biological_process											owl:Class	
GO:0009684	biolink:NamedThing	indoleacetic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants.	got7fsn_ti	indoleacetic acid synthesis|indole-3-acetate biosynthetic process|IAA biosynthetic process|indole-3-acetate biosynthesis|indole-acetic acid biosynthesis|indole-acetic acid biosynthetic process|indoleacetic acid anabolism|indole acetic acid biosynthetic process|indoleacetic acid formation|indole acetic acid biosynthesis|indoleacetic acid biosynthesis													biological_process											owl:Class	
GO:0102638	biolink:NamedThing	[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity	Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate = [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-15734|EC:2.5.1.105		molecular_function											owl:Class	
GO:0072501	biolink:NamedThing	cellular divalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of divalent inorganic anions at the level of a cell.	got7fsn_ti					Note that this term was split from 'cellular di-, tri-valent inorganic anion homeostasis ; GO:0030319' (sibling term 'cellular trivalent inorganic anion homeostasis' ; GO:0072502').		mah	2010-12-16T12:53:05Z						biological_process											owl:Class	
GO:0030002	biolink:NamedThing	cellular anion homeostasis	Any process involved in the maintenance of an internal steady state of anions at the level of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0047834	biolink:NamedThing	D-threo-aldose 1-dehydrogenase activity	Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH.	got7fsn_ti	D-threo-aldose:NAD+ 1-oxidoreductase activity|L-fucose (D-arabinose) dehydrogenase activity|(2S,3R)-aldose dehydrogenase activity|dehydrogenase, L-fucose|L-fucose dehydrogenase activity											EC:1.1.1.122|RHEA:19645|MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0060840	biolink:NamedThing	artery development	The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.	got7fsn_ti							dph	2009-08-12T10:10:51Z						biological_process											owl:Class	
GO:0001568	biolink:NamedThing	blood vessel development	The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.	got7fsn_ti														biological_process											owl:Class	
GO:0010783	biolink:NamedThing	proboscis morphogenesis, eye-antennal disc-derived	The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0047537	biolink:NamedThing	2-aminohexanoate transaminase activity	Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.	got7fsn_ti	norleucine transaminase activity|2-aminohexanoate aminotransferase activity|norleucine aminotransferase activity|norleucine (leucine) aminotransferase activity|L-2-aminohexanoate:2-oxoglutarate aminotransferase activity|leucine L-norleucine: 2-oxoglutarate aminotransferase activity											EC:2.6.1.67|MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN|RHEA:23600		molecular_function											owl:Class	
GO:0000093	biolink:NamedThing	mitotic telophase	The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0051326	biolink:NamedThing	telophase	The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.	got7fsn_ti					note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Telophase		biological_process											owl:Class	
GO:0033173	biolink:NamedThing	calcineurin-NFAT signaling cascade	Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+).	got7fsn_ti	calcineurin-NFAT signalling pathway|calcineurin-NFAT signaling pathway													biological_process											owl:Class	
GO:0097720	biolink:NamedThing	calcineurin-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression.	got7fsn_ti	calcineurin-mediated signalling|calcineurin signaling						pr	2016-08-25T15:22:21Z						biological_process											owl:Class	
GO:0035514	biolink:NamedThing	DNA demethylase activity	Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule.	got7fsn_ti							bf	2010-04-30T02:36:43Z						molecular_function											owl:Class	
GO:0060926	biolink:NamedThing	cardiac pacemaker cell development	The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.	got7fsn_ti	pacemaker cell development						dph	2009-09-29T11:51:55Z						biological_process											owl:Class	
GO:0090630	biolink:NamedThing	activation of GTPase activity	Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.	got7fsn_ti	Rab GTPase activation|Ran GTPase activation|Rho GTPase activation|Ral GTPase activation|Rap GTPase activation|Cdc42 GTPase activation|activation of Cdc42 GTPase activity|activation of Ran GTPase activity|activation of Rho GTPase activity|Ras GTPase activation|Rac GTPase activation|activation of Rab GTPase activity|activation of Ral GTPase activity|activation of ARF GTPase activity|ARF GTPase activation|activation of Ras GTPase activity|activation of Rap GTPase activity|activation of Rac GTPase activity						tb	2015-02-11T16:09:19Z			GO:0032856|GO:0032861|GO:0032860|GO:0032857|GO:0032859|GO:0032863|GO:0032864|GO:0032858|GO:0032862			biological_process											owl:Class	
GO:0043547	biolink:NamedThing	positive regulation of GTPase activity	Any process that activates or increases the activity of a GTPase.	got7fsn_ti	positive regulation of Ral GTPase activity|up regulation of Rho GTPase activity|upregulation of Rho GTPase activity|stimulation of Ran GTPase activity|stimulation of Ras GTPase activity|up-regulation of Rho GTPase activity|up-regulation of Rap GTPase activity|stimulation of ARF GTPase activity|upregulation of Ran GTPase activity|positive regulation of Rap GTPase activity|upregulation of Cdc42 GTPase activity|up regulation of GTPase activity|stimulation of Rab GTPase activity|up-regulation of GTPase activity|stimulation of Cdc42 GTPase activity|stimulation of GTPase activity|positive regulation of Ras GTPase activity|stimulation of Rac GTPase activity|up regulation of Ras GTPase activity|up regulation of Ral GTPase activity|stimulation of Ral GTPase activity|stimulation of Rho GTPase activity|activation of GTPase activity|up-regulation of Cdc42 GTPase activity|upregulation of Rap GTPase activity|upregulation of ARF GTPase activity|up regulation of Ran GTPase activity|up regulation of Rac GTPase activity|up-regulation of Ras GTPase activity|stimulation of Rap GTPase activity|up-regulation of ARF GTPase activity|upregulation of Rac GTPase activity|up-regulation of Rab GTPase activity|up-regulation of Ran GTPase activity|up regulation of Cdc42 GTPase activity|up regulation of Rab GTPase activity|positive regulation of Rac GTPase activity|upregulation of GTPase activity|up regulation of Rap GTPase activity|upregulation of Ral GTPase activity|upregulation of Ras GTPase activity|up-regulation of Ral GTPase activity|positive regulation of Rab GTPase activity|positive regulation of ARF GTPase activity|positive regulation of Rho GTPase activity|positive regulation of Cdc42 GTPase activity|up regulation of ARF GTPase activity|positive regulation of Ran GTPase activity|up-regulation of Rac GTPase activity|upregulation of Rab GTPase activity										GO:0032854|GO:0032851|GO:0032320|GO:0032321|GO:0032850|GO:0032852|GO:0032853|GO:0032855|GO:0043089			biological_process											owl:Class	
GO:0030697	biolink:NamedThing	S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.	got7fsn_ti	ribothymidyl synthase activity|tRNA (uracil-5-)-methyltransferase activity|transfer RNA uracil methylase activity|transfer RNA uracil 5-methyltransferase activity|S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity|RUMT|tRNA uracil 5-methyltransferase activity|RUMT activity|M5U-methyltransferase activity|tRNA:m(5)U54-methyltransferase activity|S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity|tRNA:m5U54-methyltransferase activity										GO:0009021	EC:2.1.1.35|RHEA:42712|MetaCyc:TRNA-URACIL-5--METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0022030	biolink:NamedThing	telencephalon glial cell migration	The orderly movement of glial cells through the telencephalon.	got7fsn_ti														biological_process											owl:Class	
GO:0022029	biolink:NamedThing	telencephalon cell migration	The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.	got7fsn_ti														biological_process											owl:Class	
GO:0048161	biolink:NamedThing	double layer follicle stage	The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus.	got7fsn_ti	mammalian oogenesis stage 4													biological_process											owl:Class	
GO:1900816	biolink:NamedThing	ochratoxin A metabolic process	The chemical reactions and pathways involving ochratoxin A.	got7fsn_ti	Ochratoxin A metabolic process|Ochratoxin A metabolism						di	2012-06-04T10:13:02Z						biological_process											owl:Class	
GO:0019937	biolink:NamedThing	protein catenane formation via N6-(L-isoaspartyl)-L-lysine, autocatalytic	The autocatalytic formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; known to occur in the capsid of some bacteriophage, such as HK97, where it is thought to provide a mechanism for stabilizing the capsid.	got7fsn_ti												RESID:AA0294		biological_process											owl:Class	
GO:0018419	biolink:NamedThing	protein catenane formation	The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain.	got7fsn_ti														biological_process											owl:Class	
GO:0071221	biolink:NamedThing	cellular response to bacterial lipopeptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.	got7fsn_ti							mah	2009-12-03T01:28:03Z						biological_process											owl:Class	
GO:0070339	biolink:NamedThing	response to bacterial lipopeptide	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0060090	biolink:NamedThing	molecular adaptor activity	The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.	got7fsn_ti	protein-containing complex scaffold activity|protein complex scaffold activity|binding, bridging										GO:0032947			molecular_function											owl:Class	
GO:0019979	biolink:NamedThing	interleukin-4 binding	Binding to interleukin-4.	got7fsn_ti	IL-4 binding													molecular_function											owl:Class	
GO:0005596	biolink:NamedThing	collagen type XIV trimer	A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.	got7fsn_ti														cellular_component											owl:Class	
GO:0031124	biolink:NamedThing	mRNA 3'-end processing	Any process involved in forming the mature 3' end of an mRNA molecule.	got7fsn_ti	mRNA 3' end processing													biological_process											owl:Class	
GO:0006397	biolink:NamedThing	mRNA processing	Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.	got7fsn_ti	mRNA maturation													biological_process											owl:Class	
GO:0072729	biolink:NamedThing	cellular response to Gentian violet	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.	got7fsn_ti	cellular response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride|cellular response to crystal violet						mah	2012-05-31T11:23:40Z						biological_process											owl:Class	
GO:0072728	biolink:NamedThing	response to Gentian violet	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.	got7fsn_ti	response to crystal violet|response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride						mah	2012-05-31T11:23:25Z						biological_process											owl:Class	
GO:0042380	biolink:NamedThing	hydroxymethylbutenyl pyrophosphate reductase activity	Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.	got7fsn_ti	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming)													molecular_function											owl:Class	
GO:0035294	biolink:NamedThing	determination of wing disc primordium	Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc.	got7fsn_ti														biological_process											owl:Class	
GO:0007445	biolink:NamedThing	determination of imaginal disc primordium	Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0044405	biolink:NamedThing	detection of host	The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	recognition of host													biological_process											owl:Class	
GO:0001831	biolink:NamedThing	trophectodermal cellular morphogenesis	The morphogenesis of trophectoderm cells.	got7fsn_ti	trophectoderm cellular morphogenesis				See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.									biological_process											owl:Class	
GO:0032350	biolink:NamedThing	regulation of hormone metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.	got7fsn_ti	regulation of hormone metabolism													biological_process											owl:Class	
GO:0019222	biolink:NamedThing	regulation of metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.	got7fsn_ti	regulation of organismal metabolic process|regulation of multicellular organismal metabolic process|regulation of metabolism										GO:0044246			biological_process											owl:Class	
GO:0102398	biolink:NamedThing	dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine  + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+.	got7fsn_ti												MetaCyc:RXN-13657		molecular_function											owl:Class	
GO:0010115	biolink:NamedThing	regulation of abscisic acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.	got7fsn_ti	regulation of abscisic acid formation|regulation of abscisic acid synthesis|regulation of abscisic acid biosynthesis|regulation of abscisic acid anabolism													biological_process											owl:Class	
GO:0043455	biolink:NamedThing	regulation of secondary metabolic process	Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.	got7fsn_ti	regulation of secondary metabolism													biological_process											owl:Class	
GO:0036222	biolink:NamedThing	XTP diphosphatase activity	Catalysis of the reaction: XTP + H2O <=> H+ + XDP + monophosphate.	got7fsn_ti	XTP pyrophosphohydrolase activity|XTP/dITP diphosphatase|XTPase activity|hypoxanthine/xanthine dNTP pyrophosphatase	https://github.com/geneontology/go-ontology/issues/19078			While XTP is not produced by cells, deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP, and dXTP. XTPase contributes to the removal of these abnormal bases from the cellular pool of nucleotide triphosphates.		bf	2012-05-08T01:47:59Z			GO:0103024	RHEA:28610|KEGG_REACTION:R02720|MetaCyc:RXN0-1603|Reactome:R-HSA-2509831|MetaCyc:RXN0-5074|EC:3.6.1.66		molecular_function											owl:Class	
GO:0048848	biolink:NamedThing	neurohypophysis morphogenesis	The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.	got7fsn_ti	posterior pituitary morphogenesis|neurophysis morphogenesis|posterior pituitary gland morphogenesis													biological_process											owl:Class	
GO:0001400	biolink:NamedThing	mating projection base	The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone.	got7fsn_ti	conjugation tube base|base of shmoo tip													cellular_component											owl:Class	
GO:0035162	biolink:NamedThing	embryonic hemopoiesis	The stages of blood cell formation that take place within the embryo.	got7fsn_ti	embryonic haemopoiesis|embryonic hematopoiesis|embryonic haematopoiesis													biological_process											owl:Class	
GO:0030097	biolink:NamedThing	hemopoiesis	The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.	got7fsn_ti	blood cell biosynthesis|haemopoiesis|hematopoiesis|blood cell formation											Wikipedia:Haematopoiesis		biological_process											owl:Class	
GO:0001101	biolink:NamedThing	response to acid chemical	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.	got7fsn_ti	response to acid anion|response to acid|response to oxoanion				This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead.									biological_process											owl:Class	
GO:0019864	biolink:NamedThing	IgG binding	Binding to an immunoglobulin of an IgG isotype.	got7fsn_ti														molecular_function											owl:Class	
GO:0045458	biolink:NamedThing	recombination within rDNA repeats	Genetic recombination within the DNA of the genes coding for ribosomal RNA.	got7fsn_ti	recombination within ribosomal DNA repeats				Note that this term was reinstated from obsolete.									biological_process											owl:Class	
GO:0047972	biolink:NamedThing	guanidinopropionase activity	Catalysis of the reaction: 3-guanidinopropanoate + H(2)O = beta-alanine + urea.	got7fsn_ti	GPase activity|GPH|3-guanidinopropanoate amidinopropionase activity											EC:3.5.3.17|KEGG_REACTION:R00913|MetaCyc:GUANIDINOPROPIONASE-RXN|RHEA:16029		molecular_function											owl:Class	
GO:0097030	biolink:NamedThing	CENP-A containing nucleosome binding	Binding to a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).	got7fsn_ti	centromere-specific nucleosome binding|centromeric nucleosome binding						pr	2011-04-01T03:19:35Z						molecular_function											owl:Class	
GO:0045311	biolink:NamedThing	invasive growth in response to pheromone	The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0036267	biolink:NamedThing	invasive filamentous growth	The growth of colonies in filamentous chains of cells into a substrate.	got7fsn_ti	invasive growth						bf	2012-07-02T01:42:24Z						biological_process											owl:Class	
GO:0010700	biolink:NamedThing	negative regulation of norepinephrine secretion	Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.	got7fsn_ti														biological_process											owl:Class	
GO:0014061	biolink:NamedThing	regulation of norepinephrine secretion	Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.	got7fsn_ti	regulation of noradrenaline secretion													biological_process											owl:Class	
GO:0044505	biolink:NamedThing	positive regulation of G protein-coupled receptor activity in other organism	A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism.	got7fsn_ti	positive regulation of G-protein coupled receptor activity in other organism|regulation of G-protein coupled receptor activity in other organism						jl	2012-02-23T04:24:17Z						biological_process											owl:Class	
GO:0097446	biolink:NamedThing	protein localization to eisosome filament	A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.	got7fsn_ti	protein localization to linear eisosome						pr	2012-12-17T09:37:49Z						biological_process											owl:Class	
GO:0044380	biolink:NamedThing	protein localization to cytoskeleton	A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.	got7fsn_ti	protein localisation to cytoskeleton						jl	2011-12-13T11:43:24Z						biological_process											owl:Class	
GO:0033894	biolink:NamedThing	ribonuclease P4 activity	Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor.	got7fsn_ti												EC:3.1.26.7|MetaCyc:3.1.26.7-RXN		molecular_function											owl:Class	
GO:0046862	biolink:NamedThing	chromoplast membrane	Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0008398	biolink:NamedThing	sterol 14-demethylase activity	Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O.	got7fsn_ti	sterol 14-alpha-demethylase activity|cytochrome P450 CYP51|sterol 14alpha-demethylase activity|lanosterol 14-alpha-demethylase activity|sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)|lanosterol 14alpha-demethylase activity|obtusufoliol 14-demethylase activity|lanosterol 14-demethylase activity|cytochrome P450 51 activity											MetaCyc:1.14.13.70-RXN|RHEA:14917|EC:1.14.13.70|Reactome:R-HSA-194678		molecular_function											owl:Class	
GO:0052927	biolink:NamedThing	CTP:tRNA cytidylyltransferase activity	Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate.	got7fsn_ti												KEGG_REACTION:R09383|EC:2.7.7.72		molecular_function											owl:Class	
GO:0070503	biolink:NamedThing	selenium-containing prosthetic group metabolic process	The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.	got7fsn_ti	selenium-containing prosthetic group metabolism													biological_process											owl:Class	
GO:0033930	biolink:NamedThing	keratan-sulfate endo-1,4-beta-galactosidase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate.	got7fsn_ti	keratan-sulfate 1,4-beta-D-galactanohydrolase activity|keratanase activity|keratan sulfate endogalactosidase activity|endo-beta-galactosidase activity											EC:3.2.1.103|MetaCyc:3.2.1.103-RXN		molecular_function											owl:Class	
GO:0015925	biolink:NamedThing	galactosidase activity	Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0043836	biolink:NamedThing	xanthine hydrolase activity	Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate.	got7fsn_ti	xanthinase activity											MetaCyc:R127-RXN		molecular_function											owl:Class	
GO:0016316	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.	got7fsn_ti	inositol polyphosphate 4-phosphatase type II activity|1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase activity										GO:0004440	Reactome:R-HSA-1676164|Reactome:R-HSA-1676162|EC:3.1.3.66|MetaCyc:3.1.3.66-RXN		molecular_function											owl:Class	
GO:0061414	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	got7fsn_ti							dph	2012-01-23T11:31:27Z						biological_process											owl:Class	
GO:0000436	biolink:NamedThing	carbon catabolite activation of transcription from RNA polymerase II promoter	Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter by carbon catabolites													biological_process											owl:Class	
GO:0050913	biolink:NamedThing	sensory perception of bitter taste	The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti	bitter taste perception													biological_process											owl:Class	
GO:0050909	biolink:NamedThing	sensory perception of taste	The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.	got7fsn_ti	sense of taste|gustation|taste perception|taste											Wikipedia:Taste		biological_process											owl:Class	
GO:0034061	biolink:NamedThing	DNA polymerase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.	got7fsn_ti	DNA nucleotidyltransferase activity|deoxynucleate polymerase activity|deoxyribonucleate nucleotidyltransferase activity|deoxyribonucleic acid polymerase activity|deoxyribonucleic polymerase activity													molecular_function											owl:Class	
GO:0020035	biolink:NamedThing	cytoadherence to microvasculature, mediated by symbiont protein	The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.	got7fsn_ti	parasite-protein-mediated cytoadherence to microvasculature|symbiont-protein-mediated cytoadherence to microvasculature|heterophilic cell adhesion involved in cytoadherence to microvasculature, mediated by parasite protein|cytoadherence to microvasculature, mediated by parasite protein	https://github.com/geneontology/go-ontology/issues/18814									GO:0043706			biological_process											owl:Class	
GO:0044406	biolink:NamedThing	adhesion of symbiont to host	The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	adhesion to other organism during symbiotic interaction|adhesion to symbiont|adhesion to other organism involved in symbiotic interaction|adhesion to host|host adhesion				This term can be used to annotate both symbiont and host organisms. Consider also annotating to biological process involved in interaction with symbiont ; GO:0051702.						GO:0051856|GO:0051825			biological_process											owl:Class	
GO:0048495	biolink:NamedThing	Roundabout binding	Binding to Roundabout (ROBO) receptor, a transmembrane receptor.	got7fsn_ti	Roundabout receptor binding													molecular_function											owl:Class	
GO:0039701	biolink:NamedThing	microtubule-dependent intracellular transport of viral material towards cell periphery	The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.	got7fsn_ti							bf	2013-11-06T16:09:57Z				VZ:1816		biological_process											owl:Class	
GO:0075519	biolink:NamedThing	microtubule-dependent intracellular transport of viral material	The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus.	got7fsn_ti							jl	2011-08-03T01:45:25Z						biological_process											owl:Class	
GO:0045764	biolink:NamedThing	positive regulation of cellular amino acid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.	got7fsn_ti	up regulation of amino acid metabolic process|upregulation of amino acid metabolic process|stimulation of amino acid metabolic process|up-regulation of amino acid metabolic process|activation of amino acid metabolic process|positive regulation of amino acid metabolism													biological_process											owl:Class	
GO:0006521	biolink:NamedThing	regulation of cellular amino acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.	got7fsn_ti	regulation of amino acid metabolism													biological_process											owl:Class	
GO:0060848	biolink:NamedThing	endothelial cell fate determination	A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	got7fsn_ti							dph	2009-08-12T11:11:14Z						biological_process											owl:Class	
GO:0008626	biolink:NamedThing	granzyme-mediated apoptotic signaling pathway	A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells.	got7fsn_ti	apoptotic signaling pathway in response to granzyme|induction of apoptosis by granzyme	http://wiki.geneontology.org/index.php/Apoptosis_Curation_Manual#Other_children_of_apoptotic_signaling_pathway												biological_process											owl:Class	
GO:0097190	biolink:NamedThing	apoptotic signaling pathway	A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	apoptotic signalling pathway|induction of apoptosis by extracellular signals				This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.		pr	2011-11-23T09:30:23Z			GO:0008624			biological_process											owl:Class	
GO:0150014	biolink:NamedThing	apical distal dendrite	Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma).	got7fsn_ti							bc	2017-12-21T12:03:28Z						cellular_component											owl:Class	
GO:0097440	biolink:NamedThing	apical dendrite	A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.	got7fsn_ti							pr	2012-12-06T13:45:18Z				NIF_Subcellular:sao273773228		cellular_component											owl:Class	
GO:1905605	biolink:NamedThing	positive regulation of blood-brain barrier permeability	Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.	got7fsn_ti	up-regulation of blood-brain barrier permeability|activation of maintenance of permeability of blood-brain barrier|positive regulation of blood/brain barrier permeability|positive regulation of BBB permeability|up-regulation of blood/brain barrier permeability|activation of maintenance of permeability of BBB|upregulation of blood-brain barrier permeability|upregulation of blood/brain barrier permeability|upregulation of BBB permeability|up-regulation of BBB permeability						als	2016-10-26T13:18:32Z						biological_process											owl:Class	
GO:1905603	biolink:NamedThing	regulation of blood-brain barrier permeability	Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.	got7fsn_ti	regulation of blood/brain barrier permeability|regulation of BBB permeability						als	2016-10-26T13:18:16Z						biological_process											owl:Class	
GO:0097418	biolink:NamedThing	neurofibrillary tangle	Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.	got7fsn_ti	star-shaped neurofibrillary tangle|flame-shaped neurofibrillary tangle				Neurofibrillary tangles have been found in aging population; their formation is increased in Alzheimer's disease patients (and in other neurological diseases) compared to normal controls (see PMID:848276 and PMID:8584267).		pr	2012-11-06T16:49:35Z				NIF_Subcellular:nlx_subcell_20090202|NIF_Subcellular:nlx_subcell_20090201|NIF_Subcellular:sao2409833926		cellular_component											owl:Class	
GO:0035118	biolink:NamedThing	embryonic pectoral fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0035138	biolink:NamedThing	pectoral fin morphogenesis	The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0004124	biolink:NamedThing	cysteine synthase activity	Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.	got7fsn_ti	OAS sulfhydrylase activity|O-acetylserine sulfhydrylase activity|O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide) activity|3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity|O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity|O-acetyl-L-serine sulfohydrolase activity|O-acetylserine (thiol)-lyase activity|acetylserine sulfhydrylase activity|O3-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide)|O-acetylserine (thiol)-lyase A activity|cysteine synthetase activity|O-acetyl-L-serine sulfhydrylase activity				Note that this function was formerly 4.2.99.8.							EC:2.5.1.47|MetaCyc:ACSERLY-RXN|RHEA:14829		molecular_function											owl:Class	
GO:0039635	biolink:NamedThing	suppression by virus of host peptidoglycan biosynthetic process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.	got7fsn_ti	viral inhibition of host peptidoglycan biosynthesis						bf	2012-08-10T14:58:12Z						biological_process											owl:Class	
GO:0039636	biolink:NamedThing	suppression by virus of host cell wall biogenesis	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts.	got7fsn_ti							bf	2012-08-10T15:04:12Z						biological_process											owl:Class	
GO:0010189	biolink:NamedThing	vitamin E biosynthetic process	The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.	got7fsn_ti	alpha-tocopherol biosynthetic process|alpha-tocopherol biosynthesis|vitamin E synthesis|vitamin E biosynthesis|tocopherol biosynthetic process|vitamin E formation|tocopherol biosynthesis|vitamin E anabolism											MetaCyc:PWY-1422		biological_process											owl:Class	
GO:0042362	biolink:NamedThing	fat-soluble vitamin biosynthetic process	The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.	got7fsn_ti	fat-soluble vitamin biosynthesis|fat-soluble vitamin synthesis|fat-soluble vitamin formation|fat-soluble vitamin anabolism													biological_process											owl:Class	
GO:0020009	biolink:NamedThing	microneme	A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell.	got7fsn_ti	sarconeme											Wikipedia:Microneme		cellular_component											owl:Class	
GO:0022858	biolink:NamedThing	alanine transmembrane transporter activity	Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0051478	biolink:NamedThing	mannosylglycerate metabolic process	The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.	got7fsn_ti	mannosylglycerate metabolism													biological_process											owl:Class	
GO:0102087	biolink:NamedThing	N-benzoyl-L-glutamate synthetase activity	Catalysis of the reaction: benzoate + L-glutamate + ATP <=> H+ + N-benzoyl-L-glutamate + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10886		molecular_function											owl:Class	
GO:0034719	biolink:NamedThing	SMN-Sm protein complex	A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.	got7fsn_ti	SMN-containing protein complex				Note that this complex is sometimes referred to as the 'SMN complex', but it should not be confused with GO:0032797.									cellular_component											owl:Class	
GO:0102938	biolink:NamedThing	orcinol O-methyltransferase activity	Catalysis of the reaction: orcinol + S-adenosyl-L-methionine  = H+ + 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-9017|EC:2.1.1.6		molecular_function											owl:Class	
GO:1990276	biolink:NamedThing	RNA 5'-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule.	got7fsn_ti							pr	2014-01-28T09:44:16Z						molecular_function											owl:Class	
GO:0043401	biolink:NamedThing	steroid hormone mediated signaling pathway	A series of molecular signals mediated by a steroid hormone binding to a receptor.	got7fsn_ti	steroid hormone mediated signalling													biological_process											owl:Class	
GO:0018959	biolink:NamedThing	aerobic phenol-containing compound metabolic process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.	got7fsn_ti	aerobic phenol-containing compound metabolism											UM-BBD_pathwayID:pba		biological_process											owl:Class	
GO:0005010	biolink:NamedThing	insulin-like growth factor-activated receptor activity	Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	IGF receptor activity|insulin-like growth factor receptor activity|IGF-activated receptor activity				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand IGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.									molecular_function											owl:Class	
GO:0097326	biolink:NamedThing	melanocyte adhesion	The attachment of a melanocyte to another cell via adhesion molecules.	got7fsn_ti							pr	2012-06-08T10:12:03Z						biological_process											owl:Class	
GO:0044107	biolink:NamedThing	cellular alcohol metabolic process	The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.	got7fsn_ti							jl	2009-07-15T01:36:19Z						biological_process											owl:Class	
GO:0033966	biolink:NamedThing	N-substituted formamide deformylase activity	Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine.	got7fsn_ti	NfdA|N-benzylformamide amidohydrolase activity											MetaCyc:3.5.1.91-RXN|RHEA:12096		molecular_function											owl:Class	
GO:0047321	biolink:NamedThing	diphosphate-protein phosphotransferase activity	Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein.	got7fsn_ti	diphosphate:microsomal-membrane-protein O-phosphotransferase activity|triphosphate:microsomal-membrane-protein phosphotransferase activity|pyrophosphate:protein phosphotransferase activity|triphosphate-protein phosphotransferase activity|pyrophosphate-protein phosphotransferase activity|DiPPT											EC:2.7.99.1|MetaCyc:2.7.99.1-RXN		molecular_function											owl:Class	
GO:0032581	biolink:NamedThing	ER-dependent peroxisome organization	A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.	got7fsn_ti	endoplasmic reticulum-dependent peroxisome organization|ER-dependent peroxisome organisation|ER-dependent peroxisome biogenesis													biological_process											owl:Class	
GO:0007031	biolink:NamedThing	peroxisome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	got7fsn_ti	peroxisome-assembly ATPase activity|peroxisome organization and biogenesis|peroxisome organisation													biological_process											owl:Class	
GO:0048737	biolink:NamedThing	imaginal disc-derived appendage development	The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0048736	biolink:NamedThing	appendage development	The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.	got7fsn_ti														biological_process											owl:Class	
GO:0014895	biolink:NamedThing	smooth muscle hypertrophy	The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.	got7fsn_ti														biological_process											owl:Class	
GO:0014896	biolink:NamedThing	muscle hypertrophy	The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.	got7fsn_ti												Wikipedia:Muscle_hypertrophy		biological_process											owl:Class	
GO:0106378	biolink:NamedThing	2-hydroxy-dATP hydrolase activity	Catalysis of the reaction: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + diphosphate.	got7fsn_ti							hjd	2021-04-23T00:14:20Z				RHEA:31583		molecular_function											owl:Class	
GO:0017157	biolink:NamedThing	regulation of exocytosis	Any process that modulates the frequency, rate or extent of exocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0044537	biolink:NamedThing	regulation of circulating fibrinogen levels	Any process that modulates the quantity of fibrinogen circulating in the bloodstream.	got7fsn_ti							jl	2012-03-21T03:15:09Z						biological_process											owl:Class	
GO:0071453	biolink:NamedThing	cellular response to oxygen levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.	got7fsn_ti	cellular response to oxygen						mah	2009-12-16T04:43:59Z						biological_process											owl:Class	
GO:0097397	biolink:NamedThing	cellular response to interleukin-32	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.	got7fsn_ti	cellular response to IL-32						pr	2012-10-23T13:23:22Z						biological_process											owl:Class	
GO:0009760	biolink:NamedThing	C4 photosynthesis	The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch.	got7fsn_ti												Wikipedia:C4_carbon_fixation		biological_process											owl:Class	
GO:0015977	biolink:NamedThing	carbon fixation	A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).	got7fsn_ti	autotrophic CO2 fixation|autotrophic CO2 fixation pathway|carbon dioxide fixation|autotrophy											Wikipedia:Carbon_fixation		biological_process											owl:Class	
GO:0030662	biolink:NamedThing	coated vesicle membrane	The lipid bilayer surrounding a coated vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0070840	biolink:NamedThing	dynein complex binding	Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.	got7fsn_ti	dynein binding						mah	2009-07-31T01:22:47Z			GO:0045502			molecular_function											owl:Class	
GO:0034944	biolink:NamedThing	3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+.	got7fsn_ti												UM-BBD_reactionID:r0986		molecular_function											owl:Class	
GO:0050496	biolink:NamedThing	peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine	The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide.	got7fsn_ti	peptidyl-L-glutamyl 5-omega-hydroxyceramide ester anabolism from peptidyl-glutamine|peptidyl-L-glutamyl 5-omega-hydroxyceramide ester formation from peptidyl-glutamine|peptidyl-L-glutamyl 5-omega-hydroxyceramide ester synthesis from peptidyl-glutamine											RESID:AA0340		biological_process											owl:Class	
GO:0007000	biolink:NamedThing	nucleolus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.	got7fsn_ti	nucleolus organisation|nucleolus organization and biogenesis													biological_process											owl:Class	
GO:0006997	biolink:NamedThing	nucleus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.	got7fsn_ti	nucleus organization and biogenesis|nuclear organization|nuclear organisation|nuclear morphology|nuclear organization and biogenesis										GO:0048287			biological_process											owl:Class	
GO:0004316	biolink:NamedThing	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+.	got7fsn_ti	3-oxoacyl-[acyl-carrier protein] reductase activity|beta-ketoacyl-acyl-carrier protein(ACP) reductase activity|(3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity|NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity|beta-ketoacyl acyl carrier protein (ACP) reductase activity|3-ketoacyl acyl carrier protein reductase activity|beta-ketoacyl-acyl carrier protein reductase activity|beta-ketoacyl thioester reductase activity|3-oxoacyl-ACPreductase activity|beta-ketoacyl reductase activity|3-oxoacyl-ACP reductase activity|beta-ketoacyl-ACP reductase activity|3-oxoacyl-acyl-carrier-protein reductase activity	https://github.com/geneontology/go-ontology/issues/21876										MetaCyc:RXN-11476|MetaCyc:RXN-10659|RHEA:17397|EC:1.1.1.100|MetaCyc:RXN-11480|MetaCyc:3-OXOACYL-ACP-REDUCT-RXN|Reactome:R-HSA-8862152		molecular_function											owl:Class	
GO:0030114	biolink:NamedThing	slime layer	A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids.	got7fsn_ti												Wikipedia:Slime_layer		cellular_component											owl:Class	
GO:0030112	biolink:NamedThing	glycocalyx	A carbohydrate rich layer at the outermost periphery of a cell.	got7fsn_ti												Wikipedia:Glycocalyx		cellular_component											owl:Class	
GO:0032866	biolink:NamedThing	D-xylose:NADP reductase activity	Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+.	got7fsn_ti	D-xylose reductase activity|xylose reductase activity											MetaCyc:RXN-8773|RHEA:27445		molecular_function											owl:Class	
GO:0004032	biolink:NamedThing	alditol:NADP+ 1-oxidoreductase activity	Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.	got7fsn_ti	polyol dehydrogenase (NADP(+)) activity|aldose reductase activity|aldehyde reductase activity											KEGG_REACTION:R02820|MetaCyc:ALDEHYDE-REDUCTASE-RXN|RHEA:12789|EC:1.1.1.21|Reactome:R-HSA-5652172|Reactome:R-HSA-196060		molecular_function											owl:Class	
GO:0021631	biolink:NamedThing	optic nerve morphogenesis	The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	got7fsn_ti	CN II morphogenesis													biological_process											owl:Class	
GO:0052614	biolink:NamedThing	uracil oxygenase activity	Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate.	got7fsn_ti	pyrimidine oxygenase activity							2010-08-26T10:11:11Z				MetaCyc:RXN0-6444|RHEA:31587		molecular_function											owl:Class	
GO:0120104	biolink:NamedThing	mitotic actomyosin contractile ring, proximal layer	The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located.	got7fsn_ti	actomyosin contractile ring, proximal layer						krc	2017-10-11T22:49:58Z						cellular_component											owl:Class	
GO:0097241	biolink:NamedThing	hematopoietic stem cell migration to bone marrow	The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.	got7fsn_ti	progenitor cell homing|hematopoietic stem cell homing|hemopoietic stem cell migration to bone marrow						pr	2012-02-09T01:08:32Z						biological_process											owl:Class	
GO:0035701	biolink:NamedThing	hematopoietic stem cell migration	The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.	got7fsn_ti	hemopoietic stem cell migration						bf	2011-02-28T03:20:36Z						biological_process											owl:Class	
GO:0016896	biolink:NamedThing	exoribonuclease activity, producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.	got7fsn_ti	exoribonuclease activity, producing 5' phosphomonoesters											EC:3.1.13.-|Reactome:R-HSA-429860		molecular_function											owl:Class	
GO:0005025	biolink:NamedThing	transforming growth factor beta receptor activity, type I	Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.	got7fsn_ti	type I transforming growth factor beta receptor activity|type I TGFbeta receptor activity|type I TGF-beta receptor activity|transforming growth factor beta ligand binding to type I receptor													molecular_function											owl:Class	
GO:0034666	biolink:NamedThing	integrin alpha2-beta1 complex	An integrin complex that comprises one alpha2 subunit and one beta1 subunit.	got7fsn_ti	ITGA2-ITGB1 complex|VLA-2 complex													cellular_component											owl:Class	
GO:0140647	biolink:NamedThing	P450-containing electron transport chain	A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways.	got7fsn_ti	P450-containing system	https://github.com/geneontology/go-ontology/issues/21455					pg	2021-05-21T08:34:01Z				Wikipedia:P450-containing_systems		biological_process											owl:Class	
GO:0022900	biolink:NamedThing	electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21455										Wikipedia:Electron_transport_chain		biological_process											owl:Class	
GO:0045067	biolink:NamedThing	positive extrathymic T cell selection	The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.	got7fsn_ti	positive extrathymic T-cell selection|positive extrathymic T cell selection|positive extrathymic T lymphocyte selection|positive extrathymic T-lymphocyte selection													biological_process											owl:Class	
GO:0043368	biolink:NamedThing	positive T cell selection	The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.	got7fsn_ti	positive T lymphocyte selection|positive T-cell selection|positive T-lymphocyte selection													biological_process											owl:Class	
GO:0005134	biolink:NamedThing	interleukin-2 receptor binding	Binding to an interleukin-2 receptor.	got7fsn_ti	IL-2|interleukin-2 receptor ligand													molecular_function											owl:Class	
GO:0019215	biolink:NamedThing	intermediate filament binding	Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.	got7fsn_ti														molecular_function											owl:Class	
GO:0008016	biolink:NamedThing	regulation of heart contraction	Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.	got7fsn_ti	regulation of cardiac contraction													biological_process											owl:Class	
GO:1903522	biolink:NamedThing	regulation of blood circulation	Any process that modulates the frequency, rate or extent of blood circulation.	got7fsn_ti	regulation of hemolymph circulation						mr	2014-10-06T18:38:56Z						biological_process											owl:Class	
GO:0045174	biolink:NamedThing	glutathione dehydrogenase (ascorbate) activity	Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.	got7fsn_ti	dehydroascorbate reductase activity|dehydroascorbic acid reductase activity|GDOR|glutathione:dehydroascorbate oxidoreductase activity|DHA reductase activity|glutathione dehydroascorbate reductase activity|dehydroascorbic reductase activity|glutathione:dehydroascorbic acid oxidoreductase activity											KEGG_REACTION:R01108|EC:1.8.5.1|MetaCyc:1.8.5.1-RXN|Reactome:R-HSA-198813|RHEA:24424		molecular_function											owl:Class	
GO:0015038	biolink:NamedThing	glutathione disulfide oxidoreductase activity	Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.	got7fsn_ti	glutathione disulphide oxidoreductase activity|glutaredoxin											Reactome:R-HSA-111746		molecular_function											owl:Class	
GO:0003259	biolink:NamedThing	cardioblast anterior-lateral migration	The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti							dph	2009-10-15T01:17:28Z						biological_process											owl:Class	
GO:0003260	biolink:NamedThing	cardioblast migration	The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti							dph	2009-10-15T01:52:25Z						biological_process											owl:Class	
GO:0034200	biolink:NamedThing	D,D-heptose 1,7-bisphosphate phosphatase activity	Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate.	got7fsn_ti												RHEA:28518|MetaCyc:RXN0-4361		molecular_function											owl:Class	
GO:0060004	biolink:NamedThing	reflex	An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.	got7fsn_ti												Wikipedia:Reflex		biological_process											owl:Class	
GO:0052827	biolink:NamedThing	inositol pentakisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate.	got7fsn_ti							ai	2011-11-29T09:55:04Z						molecular_function											owl:Class	
GO:0052745	biolink:NamedThing	inositol phosphate phosphatase activity	Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate.	got7fsn_ti							ai	2011-09-14T01:50:04Z						molecular_function											owl:Class	
GO:0032510	biolink:NamedThing	endosome to lysosome transport via multivesicular body sorting pathway	The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.	got7fsn_ti	endosome to lysosome transport via MVB sorting pathway													biological_process											owl:Class	
GO:0032262	biolink:NamedThing	pyrimidine nucleotide salvage	Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0070819	biolink:NamedThing	menaquinone-dependent protoporphyrinogen oxidase activity	Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone.	got7fsn_ti	protoporphyrinogen-IX:menaquinone oxidoreductase activity						mah	2009-07-20T02:46:06Z						molecular_function											owl:Class	
GO:0055062	biolink:NamedThing	phosphate ion homeostasis	Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0072506	biolink:NamedThing	trivalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell.	got7fsn_ti					Note that this term was split from 'di-, tri-valent inorganic anion homeostasis ; GO:0055061' (sibling term 'divalent inorganic anion homeostasis' ; GO:0072505').		mah	2010-12-16T01:39:39Z						biological_process											owl:Class	
GO:0046944	biolink:NamedThing	protein carbamoylation	The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2.	got7fsn_ti	protein amino acid carbamoylation													biological_process											owl:Class	
GO:0097738	biolink:NamedThing	substrate mycelium formation	The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate.	got7fsn_ti							pr	2016-10-18T16:21:05Z						biological_process											owl:Class	
GO:0072133	biolink:NamedThing	metanephric mesenchyme morphogenesis	The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.	got7fsn_ti							mah	2010-02-22T02:20:14Z						biological_process											owl:Class	
GO:0072131	biolink:NamedThing	kidney mesenchyme morphogenesis	The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.	got7fsn_ti							mah	2010-02-22T02:16:43Z						biological_process											owl:Class	
GO:0045068	biolink:NamedThing	negative extrathymic T cell selection	The process of elimination of extrathymically maturing T cells which react strongly with self-antigens.	got7fsn_ti	negative extrathymic T lymphocyte selection|negative extrathymic T-cell selection|negative extrathymic T-lymphocyte selection													biological_process											owl:Class	
GO:0043383	biolink:NamedThing	negative T cell selection	The process of elimination of immature T cells which react strongly with self-antigens.	got7fsn_ti	negative T-lymphocyte selection|negative T-cell selection|negative T lymphocyte selection													biological_process											owl:Class	
GO:0060056	biolink:NamedThing	mammary gland involution	The tissue remodeling that removes differentiated mammary epithelia during weaning.	got7fsn_ti														biological_process											owl:Class	
GO:0030917	biolink:NamedThing	midbrain-hindbrain boundary development	The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.	got7fsn_ti	isthmus development|isthmic organizer development|MHB development|midbrain-hindbrain orgainizer development|isthmomesencephalic boundary development													biological_process											owl:Class	
GO:0047053	biolink:NamedThing	(S)-cheilanthifoline synthase activity	Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-cheilanthifoline + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	got7fsn_ti	(S)-scoulerine oxidase (methylenedioxy-bridge-forming) activity|(S)-scoulerine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)	https://github.com/geneontology/go-ontology/issues/21133										MetaCyc:1.14.21.2-RXN|KEGG_REACTION:R03834|RHEA:20485|EC:1.14.19.65		molecular_function											owl:Class	
GO:0060320	biolink:NamedThing	rejection of self pollen	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the rejection of the self pollen by cells in the stigma.	got7fsn_ti														biological_process											owl:Class	
GO:0070913	biolink:NamedThing	Ddb1-Wdr21 complex	A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.	got7fsn_ti							mah	2009-09-09T03:47:54Z						cellular_component											owl:Class	
GO:0001522	biolink:NamedThing	pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs.	got7fsn_ti	pseudouridylation											Wikipedia:Pseudouridine|Wikipedia:Pseudouridylation		biological_process											owl:Class	
GO:0102694	biolink:NamedThing	kinetin UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + 9-(alpha-D-glucosyl)kinetin + UDP.	got7fsn_ti												MetaCyc:RXN-4732		molecular_function											owl:Class	
GO:0018455	biolink:NamedThing	alcohol dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+.	got7fsn_ti	aldehyde reductase (NADPH/NADH)|alcohol:NAD(P)+ oxidoreductase activity											UM-BBD_reactionID:r0172|EC:1.1.1.71|RHEA:10736|MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN		molecular_function											owl:Class	
GO:0060484	biolink:NamedThing	lung-associated mesenchyme development	The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.	got7fsn_ti	pulmonary mesenchyme development|lung mesenchyme development													biological_process											owl:Class	
GO:0060485	biolink:NamedThing	mesenchyme development	The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.	got7fsn_ti	mesenchymal development													biological_process											owl:Class	
GO:0030408	biolink:NamedThing	glycine formimidoyltransferase activity	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine.	got7fsn_ti	5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase activity|FIG formiminotransferase activity|formiminotransferase activity|glycine formiminotransferase activity|formiminoglycine formiminotransferase activity|formimidoyltransferase activity											MetaCyc:GLYCINE-FORMIMINOTRANSFERASE-RXN|KEGG_REACTION:R02729|RHEA:24288|EC:2.1.2.4		molecular_function											owl:Class	
GO:0102277	biolink:NamedThing	2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose exo-beta-D-glucosaminidase activity	Catalysis of the reaction: 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose + H2O = N-acetyl-D-glucosamine + D-glucosamine.	got7fsn_ti												MetaCyc:RXN-12544		molecular_function											owl:Class	
GO:0031645	biolink:NamedThing	negative regulation of nervous system process	Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.	got7fsn_ti	inhibition of neurological process|negative regulation of neurological system process|down regulation of neurological process|negative regulation of neurophysiological process|down-regulation of neurological process|negative regulation of neurological process|downregulation of neurological process													biological_process											owl:Class	
GO:0070238	biolink:NamedThing	activated T cell autonomous cell death	A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products.	got7fsn_ti	activated T lymphocyte autonomous cell death|ACAD|activated T cell apoptosis|activated T-lymphocyte autonomous cell death|activated T-cell autonomous cell death|activated cell autonomous cell death													biological_process											owl:Class	
GO:0102949	biolink:NamedThing	1,2-rhamnosyltransferase activity	Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor.	got7fsn_ti												MetaCyc:RXN-9082		molecular_function											owl:Class	
GO:0070651	biolink:NamedThing	nonfunctional rRNA decay	An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.	got7fsn_ti	NRD						mah	2009-05-28T02:22:49Z						biological_process											owl:Class	
GO:0016075	biolink:NamedThing	rRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.	got7fsn_ti	rRNA catabolism|rRNA degradation|rRNA breakdown													biological_process											owl:Class	
GO:0071472	biolink:NamedThing	cellular response to salt stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti	cellular salinity response|cellular response to ionic osmotic stress						mah	2009-12-18T11:48:23Z						biological_process											owl:Class	
GO:0019980	biolink:NamedThing	interleukin-5 binding	Binding to interleukin-5.	got7fsn_ti	IL-5 binding													molecular_function											owl:Class	
GO:0048839	biolink:NamedThing	inner ear development	The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0045511	biolink:NamedThing	interleukin-25 binding	Binding to interleukin-25.	got7fsn_ti	IL-25 binding													molecular_function											owl:Class	
GO:1990846	biolink:NamedThing	ribonucleoside-diphosphate reductase inhibitor activity	Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase.	got7fsn_ti							vw	2015-09-04T18:13:15Z						molecular_function											owl:Class	
GO:0051311	biolink:NamedThing	meiotic metaphase plate congression	The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis.	got7fsn_ti	metaphase plate congression during meiosis													biological_process											owl:Class	
GO:0045183	biolink:NamedThing	translation factor activity, non-nucleic acid binding	A translation regulator activity that does not involve binding to nucleic acids.	got7fsn_ti														molecular_function											owl:Class	
GO:0055063	biolink:NamedThing	sulfate ion homeostasis	Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell.	got7fsn_ti	sulphate ion homeostasis|sulfate homeostasis										GO:0080174			biological_process											owl:Class	
GO:0072505	biolink:NamedThing	divalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell.	got7fsn_ti					Note that this term was split from 'di-, tri-valent inorganic anion homeostasis ; GO:0055061' (sibling term 'trivalent inorganic anion homeostasis' ; GO:0072506').		mah	2010-12-16T01:39:00Z						biological_process											owl:Class	
GO:0090644	biolink:NamedThing	age-related resistance	An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR).	got7fsn_ti	developmental resistance|ARR|senescence-induced resistance|adult seedling resistance|mature seedling resistance|flowering-induced resistance|ontogenic resistance						tb	2015-05-19T10:36:38Z						biological_process											owl:Class	
GO:0038166	biolink:NamedThing	angiotensin-activated signaling pathway	The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	angiotensin II-mediated signaling pathway|angiotensin-mediated signaling pathway|angiotensin receptor signaling pathway						bf	2012-05-14T03:09:03Z						biological_process											owl:Class	
GO:0008078	biolink:NamedThing	mesodermal cell migration	The orderly movement of mesodermal cells from one site to another.	got7fsn_ti	mesoderm cell migration													biological_process											owl:Class	
GO:0042827	biolink:NamedThing	platelet dense granule	Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.	got7fsn_ti	bull's eye body|platelet dense body													cellular_component											owl:Class	
GO:0030141	biolink:NamedThing	secretory granule	A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.	got7fsn_ti	secretory vesicle				Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'.									cellular_component											owl:Class	
GO:0047107	biolink:NamedThing	gamma-guanidinobutyraldehyde dehydrogenase activity	Catalysis of the reaction: 4-guanidinobutanal + H(2)O + NAD(+) = 4-guanidinobutanoate + 2 H(+) + NADH.	got7fsn_ti	4-guanidinobutanal:NAD+ 1-oxidoreductase activity|alpha-guanidinobutyraldehyde dehydrogenase activity|4-guanidinobutyraldehyde dehydrogenase activity|GBAL dehydrogenase activity											MetaCyc:1.2.1.54-RXN|KEGG_REACTION:R03177|EC:1.2.1.54|RHEA:14381		molecular_function											owl:Class	
GO:0004029	biolink:NamedThing	aldehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.	got7fsn_ti	aldehyde:NAD+ oxidoreductase activity|NAD-dependent 4-hydroxynonenal dehydrogenase activity|NAD-linked aldehyde dehydrogenase activity|NAD-dependent aldehyde dehydrogenase activity|m-methylbenzaldehyde dehydrogenase activity|CoA-independent aldehyde dehydrogenase activity|aldehyde dehydrogenase (NAD+)|propionaldehyde dehydrogenase activity|NAD-aldehyde dehydrogenase activity											Reactome:R-HSA-6808496|EC:1.2.1.3|Reactome:R-HSA-71723|Reactome:R-HSA-6808487|RHEA:16185|Reactome:R-HSA-6813749|Reactome:R-HSA-380608|Wikipedia:Aldehyde_dehydrogenase_(NAD+)|Reactome:R-HSA-5692261|Reactome:R-HSA-71691|Reactome:R-HSA-5696091|MetaCyc:ALDHDEHYDROG-RXN|Reactome:R-HSA-389609|UM-BBD_enzymeID:e0024		molecular_function											owl:Class	
GO:0000289	biolink:NamedThing	nuclear-transcribed mRNA poly(A) tail shortening	Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.	got7fsn_ti	mRNA deadenylation|3' to 5' mRNA deadenylation|nuclear mRNA poly(A) tail shortening													biological_process											owl:Class	
GO:0043250	biolink:NamedThing	sodium-dependent organic anion transmembrane transporter activity	Enables the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner.	got7fsn_ti														molecular_function											owl:Class	
GO:0034958	biolink:NamedThing	aminohydroquinone monooxygenase activity	Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3.	got7fsn_ti												UM-BBD_reactionID:r1497|EC:3.5.99.-		molecular_function											owl:Class	
GO:0016810	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.	got7fsn_ti	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds											EC:3.5.-.-|Reactome:R-HSA-6803753		molecular_function											owl:Class	
GO:0097465	biolink:NamedThing	somatic spine	Spine emanating from the cell soma of a neuron.	got7fsn_ti							pr	2012-12-21T08:02:37Z				NIF_Subcellular:sao2048514053		cellular_component											owl:Class	
GO:0044309	biolink:NamedThing	neuron spine	A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.	got7fsn_ti	spine						jl	2010-02-05T04:25:10Z				NIF_Subcellular:sao1145756102		cellular_component											owl:Class	
GO:0032358	biolink:NamedThing	oxidized pyrimidine DNA binding	Binding to a DNA region containing an oxidized pyrimidine residue.	got7fsn_ti	oxidised pyrimidine DNA binding|oxidized pyrimidine nucleobase DNA binding|oxidized pyrimidine base DNA binding													molecular_function											owl:Class	
GO:0032356	biolink:NamedThing	oxidized DNA binding	Binding to a DNA region containing an oxidized residue.	got7fsn_ti	oxidised DNA binding													molecular_function											owl:Class	
GO:0060464	biolink:NamedThing	lung lobe formation	The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.	got7fsn_ti														biological_process											owl:Class	
GO:0019235	biolink:NamedThing	sensory perception of slow pain	The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction.	got7fsn_ti														biological_process											owl:Class	
GO:0019233	biolink:NamedThing	sensory perception of pain	The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.	got7fsn_ti	nociception|perception of physiological pain											Wikipedia:Nociception		biological_process											owl:Class	
GO:0061712	biolink:NamedThing	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase	Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine.	got7fsn_ti							dph	2015-06-23T08:47:10Z				EC:2.8.4.5|MetaCyc:RXN-14531|RHEA:37075		molecular_function											owl:Class	
GO:0009902	biolink:NamedThing	chloroplast relocation	The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery.	got7fsn_ti	chloroplast movement													biological_process											owl:Class	
GO:0051667	biolink:NamedThing	establishment of plastid localization	The directed movement of a plastid to a specific location in the cell.	got7fsn_ti	establishment of plastid localisation													biological_process											owl:Class	
GO:0021556	biolink:NamedThing	central nervous system formation	The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	got7fsn_ti														biological_process											owl:Class	
GO:0044486	biolink:NamedThing	modulation of transmission of nerve impulse in other organism	The process in which an organism effects a change in the transmission of a nerve impulse in another organism.	got7fsn_ti	modulation of conduction of nerve impulse in other organism|regulation of transmission of nerve impulse in other organism						jl	2012-01-26T04:03:31Z						biological_process											owl:Class	
GO:0120165	biolink:NamedThing	perithecium development	The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.	got7fsn_ti							krc	2018-05-17T17:17:44Z						biological_process											owl:Class	
GO:0030582	biolink:NamedThing	reproductive fruiting body development	The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores.	got7fsn_ti	fruiting body formation				This term describes the development of a fruiting body that is a spore-bearing organ.  It is not intended to describe the development of myxococcal fruiting bodies.									biological_process											owl:Class	
GO:0002078	biolink:NamedThing	membrane fusion involved in acrosome reaction	The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.	got7fsn_ti	membrane fusion involved in the acrosomal reaction													biological_process											owl:Class	
GO:0032002	biolink:NamedThing	interleukin-28 receptor complex	A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1).	got7fsn_ti	IL-28 receptor complex													cellular_component											owl:Class	
GO:0060177	biolink:NamedThing	regulation of angiotensin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin.	got7fsn_ti	regulation of angiotensin metabolism													biological_process											owl:Class	
GO:0051246	biolink:NamedThing	regulation of protein metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.	got7fsn_ti	regulation of protein metabolism													biological_process											owl:Class	
GO:0043936	biolink:NamedThing	asexual sporulation resulting in formation of a cellular spore	The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	got7fsn_ti	asexual sporulation resulting in the formation of a viable spore|asexual reproduction resulting in the formation of a cellular spore													biological_process											owl:Class	
GO:0030436	biolink:NamedThing	asexual sporulation	The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi.	got7fsn_ti	asexual spore formation|mitotic spore formation|mitotic sporulation|asexual reproductive sporulation													biological_process											owl:Class	
GO:0042255	biolink:NamedThing	ribosome assembly	The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.	got7fsn_ti	ribosomal subunit assembly										GO:0042257			biological_process											owl:Class	
GO:0097196	biolink:NamedThing	Shu complex	A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p.	got7fsn_ti							pr	2011-12-01T05:11:08Z						cellular_component											owl:Class	
GO:0051873	biolink:NamedThing	killing by host of symbiont cells	Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	disruption by host of symbiont cells	https://github.com/geneontology/go-ontology/issues/18719									GO:0051852			biological_process											owl:Class	
GO:0051883	biolink:NamedThing	killing of cells in other organism involved in symbiotic interaction	Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	killing of cells in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0034304	biolink:NamedThing	actinomycete-type spore formation	The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.	got7fsn_ti														biological_process											owl:Class	
GO:0051065	biolink:NamedThing	CTP reductase activity	Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.	got7fsn_ti	CTP reduction											EC:1.17.4.-		molecular_function											owl:Class	
GO:0008998	biolink:NamedThing	ribonucleoside-triphosphate reductase activity	Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.	got7fsn_ti	2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase activity|2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase activity|ribonucleotide reductase activity											MetaCyc:1.17.4.2-RXN|RHEA:12701|EC:1.17.4.2		molecular_function											owl:Class	
GO:0097475	biolink:NamedThing	motor neuron migration	The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.	got7fsn_ti							pr	2013-04-23T13:00:46Z						biological_process											owl:Class	
GO:0140515	biolink:NamedThing	mitotic nuclear bridge organization	A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19948					pg	2020-09-09T14:04:33Z						biological_process											owl:Class	
GO:0101024	biolink:NamedThing	mitotic nuclear membrane organization	A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis.	got7fsn_ti	nuclear membrane organization involved in mitotic nuclear division	https://github.com/geneontology/go-ontology/issues/19949			This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown.									biological_process											owl:Class	
GO:0080016	biolink:NamedThing	(-)-E-beta-caryophyllene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate.	got7fsn_ti												EC:4.2.3.57|MetaCyc:RXN-8414|RHEA:28294		molecular_function											owl:Class	
GO:0010334	biolink:NamedThing	sesquiterpene synthase activity	Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons.	got7fsn_ti														molecular_function											owl:Class	
GO:0019821	biolink:NamedThing	P3 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content.	got7fsn_ti	peroxisome vesicle				Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'.									cellular_component											owl:Class	
GO:0051666	biolink:NamedThing	actin cortical patch localization	Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.	got7fsn_ti	actin cortical patch localisation|establishment and maintenance of actin cortical patch localization													biological_process											owl:Class	
GO:0051641	biolink:NamedThing	cellular localization	A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.	got7fsn_ti	single-organism cellular localization|establishment and maintenance of cellular localization|localization within cell|establishment and maintenance of localization in cell or cell membrane|single organism cellular localization|cellular localisation|intracellular localization						jl	2013-12-18T14:04:32Z			GO:1902580			biological_process											owl:Class	
GO:0052895	biolink:NamedThing	N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity	Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide.	got7fsn_ti	N1-acetylspermine oxidase activity											MetaCyc:POLYAMINE-OXIDASE-RXN|EC:1.5.3.16		molecular_function											owl:Class	
GO:0018178	biolink:NamedThing	peptidyl-threonine adenylylation	The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine.	got7fsn_ti	peptidyl-threonine adenylation											RESID:AA0267		biological_process											owl:Class	
GO:0075134	biolink:NamedThing	induction by symbiont of host calcium or calmodulin-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host calcium or calmodulin-mediated signal transduction|positive regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075104".									biological_process											owl:Class	
GO:0051391	biolink:NamedThing	tRNA acetylation	The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti														biological_process											owl:Class	
GO:1990884	biolink:NamedThing	RNA acetylation	The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule.	got7fsn_ti							mah	2015-10-28T16:28:08Z						biological_process											owl:Class	
GO:0070661	biolink:NamedThing	leukocyte proliferation	The expansion of a leukocyte population by cell division.	got7fsn_ti							mah	2009-05-28T05:25:28Z						biological_process											owl:Class	
GO:0072298	biolink:NamedThing	regulation of metanephric glomerulus development	Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.	got7fsn_ti							mah	2010-04-09T05:03:14Z						biological_process											owl:Class	
GO:0044289	biolink:NamedThing	mitochondrial inner-outer membrane contact site	Sites of close apposition of the inner and outer mitochondrial membrane.	got7fsn_ti	contact site|bridge contact site	https://github.com/geneontology/go-ontology/issues/18994					jl	2010-02-04T02:25:11Z			GO:0044285			cellular_component											owl:Class	
GO:0007630	biolink:NamedThing	jump response	The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0018909	biolink:NamedThing	dodecyl sulfate metabolic process	The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.	got7fsn_ti	dodecyl sulfate metabolism|dodecyl sulphate metabolic process|dodecyl sulphate metabolism											UM-BBD_pathwayID:dds		biological_process											owl:Class	
GO:0061051	biolink:NamedThing	positive regulation of cell growth involved in cardiac muscle cell development	Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.	got7fsn_ti							dph	2010-02-25T01:08:08Z						biological_process											owl:Class	
GO:0051155	biolink:NamedThing	positive regulation of striated muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.	got7fsn_ti	upregulation of striated muscle cell differentiation|activation of striated muscle cell differentiation|stimulation of striated muscle cell differentiation|up-regulation of striated muscle cell differentiation|up regulation of striated muscle cell differentiation													biological_process											owl:Class	
GO:0042395	biolink:NamedThing	ecdysis, collagen and cuticulin-based cuticle	The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates.	got7fsn_ti														biological_process											owl:Class	
GO:0021568	biolink:NamedThing	rhombomere 2 development	The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0021546	biolink:NamedThing	rhombomere development	The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.	got7fsn_ti														biological_process											owl:Class	
GO:0036456	biolink:NamedThing	L-methionine-(S)-S-oxide reductase activity	Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O.	got7fsn_ti							bf	2013-11-27T11:07:19Z				RHEA:19995		molecular_function											owl:Class	
GO:0033744	biolink:NamedThing	L-methionine:thioredoxin-disulfide S-oxidoreductase activity	Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin.	got7fsn_ti	methionine-S-oxide reductase activity|acetylmethionine sulfoxide reductase activity|methionine sulfoxide reductase activity|L-methionine:oxidized-thioredoxin S-oxidoreductase activity|free-methionine (S)-S-oxide reductase activity|fSMsr|L-methionine-(S)-S-oxide reductase activity|methyl sulfoxide reductase I and II activity										GO:0000317	KEGG_REACTION:R07606|MetaCyc:1.8.4.13-RXN|RHEA:19993|EC:1.8.4.13		molecular_function											owl:Class	
GO:0050162	biolink:NamedThing	oxalate oxidase activity	Catalysis of the reaction: 2 H(+) + O(2) + oxalate = 2 CO(2) + H(2)O(2).	got7fsn_ti	oxalate:oxygen oxidoreductase activity|oxalic acid oxidase activity|aero-oxalo dehydrogenase activity											RHEA:21880|MetaCyc:OXALATE-OXIDASE-RXN|EC:1.2.3.4|KEGG_REACTION:R00273		molecular_function											owl:Class	
GO:0018744	biolink:NamedThing	limonene-1,2-epoxide hydrolase activity	Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.	got7fsn_ti	limonene oxide hydrolase activity											RHEA:10700|MetaCyc:3.3.2.8-RXN|UM-BBD_reactionID:r0734|EC:3.3.2.8		molecular_function											owl:Class	
GO:0030948	biolink:NamedThing	negative regulation of vascular endothelial growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.	got7fsn_ti	down regulation of vascular endothelial growth factor receptor signaling pathway|inhibition of vascular endothelial growth factor receptor signaling pathway|downregulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of vascular endothelial growth factor receptor signalling pathway|negative regulation of VEGF receptor signaling pathway|negative regulation of VEGF receptor signalling pathway|down-regulation of vascular endothelial growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0090288	biolink:NamedThing	negative regulation of cellular response to growth factor stimulus	Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	got7fsn_ti							tb	2010-02-18T03:01:25Z						biological_process											owl:Class	
GO:0071478	biolink:NamedThing	cellular response to radiation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.	got7fsn_ti	cellular response to radiation stimulus|cellular response to electromagnetic radiation stimulus				Note that 'radiation' refers to electromagnetic radiation of any wavelength.		mah	2009-12-18T01:59:37Z						biological_process											owl:Class	
GO:0071214	biolink:NamedThing	cellular response to abiotic stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.	got7fsn_ti	cellular response to abiotic stress				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-03T01:02:11Z						biological_process											owl:Class	
GO:0075120	biolink:NamedThing	suppression by symbiont of host G protein-coupled receptor signal transduction	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host G-protein coupled receptor protein signal transduction|negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit|negative regulation by symbiont of host G protein-coupled receptor signal transduction|negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit|negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont G protein-coupled receptor signal transduction ; GO:0075089".						GO:0075126|GO:0075129|GO:0075123			biological_process											owl:Class	
GO:0075114	biolink:NamedThing	suppression by symbiont of host transmembrane receptor-mediated signal transduction	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host transmembrane receptor-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075083".									biological_process											owl:Class	
GO:0048596	biolink:NamedThing	embryonic camera-type eye morphogenesis	The process in which the anatomical structures of the eye are generated and organized during embryonic development.	got7fsn_ti	embryonic eye morphogenesis													biological_process											owl:Class	
GO:0048048	biolink:NamedThing	embryonic eye morphogenesis	The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0001097	biolink:NamedThing	TFIIH-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	got7fsn_ti	TFIIH-class transcription factor binding						krc	2010-10-28T02:51:41Z						molecular_function											owl:Class	
GO:0060688	biolink:NamedThing	regulation of morphogenesis of a branching structure	Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.	got7fsn_ti							dph	2009-06-05T12:41:44Z						biological_process											owl:Class	
GO:0022603	biolink:NamedThing	regulation of anatomical structure morphogenesis	Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.	got7fsn_ti	regulation of morphogenesis													biological_process											owl:Class	
GO:0001769	biolink:NamedThing	establishment of B cell polarity	The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.	got7fsn_ti	establishment of B-cell polarity|B-cell polarization|establishment of B lymphocyte polarity|B cell polarization|establishment of B-lymphocyte polarity|B lymphocyte polarization				Note that 'antigen displaying cell' in this term encompasses cell types such as follicular dendritic cells which display the unprocessed antigens of a B cell, leading to activation of the B cells and antigen uptake and processing by the B cells.									biological_process											owl:Class	
GO:0001767	biolink:NamedThing	establishment of lymphocyte polarity	The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.	got7fsn_ti	lymphocyte polarization													biological_process											owl:Class	
GO:0032140	biolink:NamedThing	single adenine insertion binding	Binding to a double-stranded DNA region containing a single adenine insertion or a deletion that results in an unpaired adenine.	got7fsn_ti														molecular_function											owl:Class	
GO:0032138	biolink:NamedThing	single base insertion or deletion binding	Binding to a double-stranded DNA region containing a single base insertion or deletion.	got7fsn_ti	single base insertion binding													molecular_function											owl:Class	
GO:0031232	biolink:NamedThing	extrinsic component of external side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to external leaflet of plasma membrane|extrinsic to external side of plasma membrane													cellular_component											owl:Class	
GO:1901276	biolink:NamedThing	tartrate catabolic process	The chemical reactions and pathways resulting in the breakdown of tartrate.	got7fsn_ti	tartrate catabolism|tartrate breakdown|tartrate degradation						yaf	2012-08-17T14:52:40Z						biological_process											owl:Class	
GO:0009056	biolink:NamedThing	catabolic process	The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.	got7fsn_ti	single-organism catabolic process|degradation|breakdown|catabolism|multicellular organismal catabolic process						jl	2012-10-17T15:52:35Z			GO:0044243|GO:0044712	Wikipedia:Catabolism		biological_process											owl:Class	
GO:0070647	biolink:NamedThing	protein modification by small protein conjugation or removal	A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.	got7fsn_ti							mah	2009-05-11T02:54:03Z						biological_process											owl:Class	
GO:0038182	biolink:NamedThing	G protein-coupled bile acid receptor activity	Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G-protein coupled bile acid receptor activity|cell surface bile acid receptor|membrane bile acid receptor activity						bf	2013-05-16T10:29:42Z				Wikipedia:G_protein-coupled_bile_acid_receptor		molecular_function											owl:Class	
GO:0033405	biolink:NamedThing	UCU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UCU codon.	got7fsn_ti	TCT codon-amino acid adaptor activity|serine tRNA				Note that in the standard genetic code, TCT codes for serine.									molecular_function											owl:Class	
GO:0033448	biolink:NamedThing	AGG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AGG codon.	got7fsn_ti	arginine tRNA				Note that in the standard genetic code, AGG codes for arginine.									molecular_function											owl:Class	
GO:0008746	biolink:NamedThing	NAD(P)+ transhydrogenase activity	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+.	got7fsn_ti	NADH transhydrogenase|NADPH-NAD oxidoreductase|NADH-NADP-transhydrogenase|pyridine nucleotide transferase|NADPH:NAD+ transhydrogenase|nicotinamide adenine dinucleotide (phosphate) transhydrogenase|H+-thase|energy-linked transhydrogenase|NAD transhydrogenase|NADPH-NAD transhydrogenase											RHEA:11692|Reactome:R-HSA-450971|KEGG_REACTION:R00112|EC:1.6.1.1		molecular_function											owl:Class	
GO:0016652	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.	got7fsn_ti	oxidoreductase activity, acting on NAD or NADPH, NAD or NADP as acceptor											EC:1.6.1.-		molecular_function											owl:Class	
GO:0051704	biolink:NamedThing	multi-organism process	A biological process which involves another organism of the same or different species.	got7fsn_ti	interaction between organisms|physiological interaction with other organism|physiological interaction between organisms										GO:0051706			biological_process											owl:Class	
GO:0070431	biolink:NamedThing	nucleotide-binding oligomerization domain containing 2 signaling pathway	Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2).	got7fsn_ti	NOD2 signaling pathway|nucleotide-binding oligomerization domain containing 2 signalling pathway													biological_process											owl:Class	
GO:0022612	biolink:NamedThing	gland morphogenesis	The process in which the anatomical structures of a gland are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0018538	biolink:NamedThing	epoxide carboxylase activity	Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+.	got7fsn_ti														molecular_function											owl:Class	
GO:0016651	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on NADH or NADPH|NAD(P)H dehydrogenase|oxidoreductase activity, acting on NADH or NADPH, other acceptor											Reactome:R-HSA-109343|EC:1.6.-.-|Reactome:R-HSA-8956458		molecular_function											owl:Class	
GO:0018126	biolink:NamedThing	protein hydroxylation	The addition of a hydroxy group to a protein amino acid.	got7fsn_ti	protein amino acid hydroxylation													biological_process											owl:Class	
GO:1900969	biolink:NamedThing	negative regulation of sarcinapterin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process.	got7fsn_ti	downregulation of sarcinapterin metabolism|down regulation of sarcinapterin metabolic process|inhibition of sarcinapterin metabolic process|down-regulation of sarcinapterin metabolic process|downregulation of sarcinapterin metabolic process|negative regulation of sarcinapterin metabolism|down-regulation of sarcinapterin metabolism|down regulation of sarcinapterin metabolism|inhibition of sarcinapterin metabolism						tt	2012-06-14T03:58:35Z						biological_process											owl:Class	
GO:0045863	biolink:NamedThing	negative regulation of pteridine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine.	got7fsn_ti	down regulation of pteridine metabolic process|downregulation of pteridine metabolic process|inhibition of pteridine metabolic process|down-regulation of pteridine metabolic process|negative regulation of pteridine metabolism													biological_process											owl:Class	
GO:0044625	biolink:NamedThing	envenomation resulting in negative regulation of cell migration in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of cell migration in the bitten organism.	got7fsn_ti							jl	2012-07-04T05:07:16Z						biological_process											owl:Class	
GO:0002901	biolink:NamedThing	mature B cell apoptotic process	Any apoptotic process in a B cell that is mature, having left the bone marrow.	got7fsn_ti	mature B-lymphocyte programmed cell death by apoptosis|apoptosis of mature B lymphocytes|programmed cell death, mature B lymphocytes|mature B-cell programmed cell death by apoptosis|programmed cell death of mature B-lymphocytes by apoptosis|apoptosis of mature B-lymphocytes|mature B lymphocyte apoptosis|programmed cell death of mature B-cells by apoptosis|mature B cell apoptosis|mature B-cell apoptosis|programmed cell death, mature B-lymphocytes|mature B-lymphocyte apoptosis|programmed cell death of mature B lymphocytes by apoptosis|mature B cell programmed cell death by apoptosis|programmed cell death of mature B cells by apoptosis|apoptosis of mature B cells|programmed cell death, mature B cells|apoptosis of mature B-cells|mature B lymphocyte programmed cell death by apoptosis|programmed cell death, mature B-cells													biological_process											owl:Class	
GO:0001783	biolink:NamedThing	B cell apoptotic process	Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.	got7fsn_ti	programmed cell death of B-lymphocytes by apoptosis|programmed cell death, B-lymphocytes|B-lymphocyte programmed cell death by apoptosis|programmed cell death, B-cells|programmed cell death of B cells by apoptosis|B lymphocyte apoptosis|apoptosis of B lymphocytes|B-cell apoptosis|B-cell programmed cell death by apoptosis|apoptosis of B cells|B cell programmed cell death by apoptosis|programmed cell death, B lymphocytes|B lymphocyte programmed cell death by apoptosis|apoptosis of B-cells|programmed cell death of B lymphocytes by apoptosis|B cell apoptosis|programmed cell death of B-cells by apoptosis|programmed cell death, B cells|B-lymphocyte apoptosis|apoptosis of B-lymphocytes													biological_process											owl:Class	
GO:0031288	biolink:NamedThing	sorocarp morphogenesis	The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	fruiting body morphogenesis													biological_process											owl:Class	
GO:0021961	biolink:NamedThing	posterior commissure morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.	got7fsn_ti														biological_process											owl:Class	
GO:0044359	biolink:NamedThing	modulation of molecular function in other organism	The process in which an organism effects a change in the function of proteins in a second organism.	got7fsn_ti							jl	2011-10-27T01:28:16Z						biological_process											owl:Class	
GO:0009453	biolink:NamedThing	energy taxis	The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates.	got7fsn_ti	taxis in response to energy source|energytaxis													biological_process											owl:Class	
GO:0042330	biolink:NamedThing	taxis	The directed movement of a motile cell or organism in response to an external stimulus.	got7fsn_ti	directed movement in response to stimulus											Wikipedia:Taxis		biological_process											owl:Class	
GO:0070414	biolink:NamedThing	trehalose metabolism in response to heat stress	The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	got7fsn_ti	trehalose metabolic process involved in response to heat stress													biological_process											owl:Class	
GO:0002192	biolink:NamedThing	IRES-dependent translational initiation of linear mRNA	The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.	got7fsn_ti							hjd	2011-08-11T02:32:45Z						biological_process											owl:Class	
GO:0110017	biolink:NamedThing	cap-independent translational initiation of linear mRNA	The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.	got7fsn_ti							kmv	2017-06-08T15:13:55Z						biological_process											owl:Class	
GO:0038020	biolink:NamedThing	insulin receptor recycling	The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.	got7fsn_ti							bf	2011-06-23T04:52:05Z						biological_process											owl:Class	
GO:0001881	biolink:NamedThing	receptor recycling	The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.	got7fsn_ti														biological_process											owl:Class	
GO:1990968	biolink:NamedThing	modulation by host of RNA binding by virus	A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA.	got7fsn_ti	modulation by host of viral protein:RNA interaction				Note that the bound RNA may originate from the virus or another organism, including the host.		bf	2016-06-21T11:56:10Z						biological_process											owl:Class	
GO:1905214	biolink:NamedThing	regulation of RNA binding	Any process that modulates the frequency, rate or extent of RNA binding.	got7fsn_ti							bf	2016-06-06T10:20:56Z						biological_process											owl:Class	
GO:0140110	biolink:NamedThing	transcription regulator activity	A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13588					pg	2017-10-18T07:05:44Z						molecular_function											owl:Class	
GO:0010621	biolink:NamedThing	negative regulation of transcription by transcription factor localization	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.	got7fsn_ti	negative regulation of transcription by transcription factor localisation													biological_process											owl:Class	
GO:0097177	biolink:NamedThing	mitochondrial ribosome binding	Binding to a mitochondrial ribosome.	got7fsn_ti							pr	2011-10-11T03:03:03Z						molecular_function											owl:Class	
GO:0043022	biolink:NamedThing	ribosome binding	Binding to a ribosome.	got7fsn_ti	ribosome receptor activity										GO:0030376			molecular_function											owl:Class	
GO:0002425	biolink:NamedThing	tolerance induction in urogenital tract	Tolerance induction taking place in the urogenital tract.	got7fsn_ti														biological_process											owl:Class	
GO:0002427	biolink:NamedThing	mucosal tolerance induction	Tolerance induction taking place in the mucosal tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0120044	biolink:NamedThing	stereocilium base	The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium.	got7fsn_ti	stereocilium taper						krc	2017-05-15T20:45:06Z						cellular_component											owl:Class	
GO:0031330	biolink:NamedThing	negative regulation of cellular catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.	got7fsn_ti	negative regulation of cellular degradation|negative regulation of cellular catabolism|inhibition of cellular catabolic process|down regulation of cellular catabolic process|down-regulation of cellular catabolic process|downregulation of cellular catabolic process|negative regulation of cellular breakdown													biological_process											owl:Class	
GO:0009895	biolink:NamedThing	negative regulation of catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.	got7fsn_ti	negative regulation of catabolism|down regulation of catabolic process|downregulation of catabolic process|inhibition of catabolic process|down-regulation of catabolic process|negative regulation of degradation|negative regulation of breakdown													biological_process											owl:Class	
GO:0019490	biolink:NamedThing	2-aminobenzenesulfonate desulfonation	The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.	got7fsn_ti	2-aminobenzenesulphonate desulphonation											MetaCyc:2ASDEG-PWY		biological_process											owl:Class	
GO:0018868	biolink:NamedThing	2-aminobenzenesulfonate metabolic process	The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.	got7fsn_ti	2-aminobenzenesulfonate metabolism|2-aminobenzenesulphonate metabolism|2-aminobenzenesulphonate metabolic process											UM-BBD_pathwayID:abs		biological_process											owl:Class	
GO:0075503	biolink:NamedThing	fusion of virus membrane with host macropinosome membrane	Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm.	got7fsn_ti	viral entry into host cell via macropinocytosis followed by membrane fusion with the host macropinosome membrane|viral entry into host cell via macropinocytosis followed by membrane fusion with the endosome membrane						jl	2010-06-02T02:45:47Z						biological_process											owl:Class	
GO:0039654	biolink:NamedThing	fusion of virus membrane with host endosome membrane	Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell.	got7fsn_ti	fusion of virus membrane with host endosomal membrane|viral penetration via endocytosis followed by caveolae-mediated membrane fusion with the endosome membrane|viral entry into host cell via caveolin-mediated endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via caveolae-mediated endocytosis followed by membrane fusion with the endosome membrane|viral penetration via endocytosis followed by clathrin-mediated membrane fusion with the endosome membrane|viral entry into host cell via endocytosis followed by membrane fusion with host endosome|viral entry into host cell via endocytosis followed by membrane fusion with the endosome membrane						bf	2013-06-20T14:24:05Z			GO:0075501|GO:0075517	VZ:992		biological_process											owl:Class	
GO:1990860	biolink:NamedThing	Pho85-Pho80 CDK-cyclin complex	A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.	got7fsn_ti							rb	2015-09-24T17:53:50Z						cellular_component											owl:Class	
GO:0008212	biolink:NamedThing	mineralocorticoid metabolic process	The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance.	got7fsn_ti	mineralocorticoid metabolism													biological_process											owl:Class	
GO:0008202	biolink:NamedThing	steroid metabolic process	The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	got7fsn_ti	steroid metabolism											Wikipedia:Steroid_metabolism		biological_process											owl:Class	
GO:0004510	biolink:NamedThing	tryptophan 5-monooxygenase activity	Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.	got7fsn_ti	indoleacetic acid-5-hydroxylase activity|L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)|tryptophan 5-hydroxylase activity|L-tryptophan hydroxylase activity|tryptophan hydroxylase activity											MetaCyc:TRYPTOPHAN-5-MONOOXYGENASE-RXN|RHEA:16709|Reactome:R-HSA-209828|EC:1.14.16.4		molecular_function											owl:Class	
GO:0039612	biolink:NamedThing	modulation by virus of host protein phosphorylation	Any viral process that modulates the frequency, rate or extent of phosphorylation of viral or host proteins in a host.	got7fsn_ti							bf	2012-07-06T11:13:59Z						biological_process											owl:Class	
GO:0019054	biolink:NamedThing	modulation by virus of host cellular process	The process in which a virus effects a change in the processes and activities of its host organism.	got7fsn_ti	regulation of cellular process in host by virus|modulation of cellular process in host by virus|regulation by virus of host cellular process|viral host cell process manipulation|regulation of host cellular process by virus|modification by virus of host cellular process|modulation by virus of host process													biological_process											owl:Class	
GO:0021945	biolink:NamedThing	positive regulation of cerebellar granule cell migration by calcium	The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration.	got7fsn_ti	calcium-mediated up regulation of granule cell migration|calcium-mediated upregulation of granule cell migration|calcium-mediated up-regulation of granule cell migration|calcium-mediated activation of granule cell migration|calcium-mediated stimulation of granule cell migration|calcium-mediated positive regulation of granule cell migration													biological_process											owl:Class	
GO:0030335	biolink:NamedThing	positive regulation of cell migration	Any process that activates or increases the frequency, rate or extent of cell migration.	got7fsn_ti	stimulation of cell migration|activation of cell migration|upregulation of cell migration|up regulation of cell migration|up-regulation of cell migration													biological_process											owl:Class	
GO:1990020	biolink:NamedThing	recurrent axon collateral	Axon collateral that ramifies in the area of the soma of the cell of origin.	got7fsn_ti	recurrent collateral						pr	2013-01-10T16:04:31Z				NIF_Subcellular:sao1642494436		cellular_component											owl:Class	
GO:0044303	biolink:NamedThing	axon collateral	Any of the smaller branches of an axon that emanate from the main axon cylinder.	got7fsn_ti							jl	2010-02-05T11:29:04Z				NIF_Subcellular:sao1470140754		cellular_component											owl:Class	
GO:0061758	biolink:NamedThing	2-hydroxyglutarate dehydrogenase activity, forward reaction	Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor.	got7fsn_ti	alpha-ketoglutarate reductase activity, reverse reaction						dph	2016-03-07T08:28:58Z				RHEA:21253		molecular_function											owl:Class	
GO:0047545	biolink:NamedThing	2-hydroxyglutarate dehydrogenase activity	Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.	got7fsn_ti	hydroxyglutaric dehydrogenase activity|(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase|alpha-hydroxyglutarate oxidoreductase activity|(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase|alpha-hydroxyglutarate dehydrogenase (NAD+ specific)|L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase|L-alpha-hydroxyglutarate dehydrogenase activity|alpha-hydroxyglutarate dehydrogenase activity											Reactome:R-HSA-880050|RHEA:21252|EC:1.1.99.2|MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0018750	biolink:NamedThing	biuret amidohydrolase activity	Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3.	got7fsn_ti												EC:3.5.1.84|UM-BBD_reactionID:r0846|RHEA:17525		molecular_function											owl:Class	
GO:0000138	biolink:NamedThing	Golgi trans cisterna	The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.	got7fsn_ti	late Golgi													cellular_component											owl:Class	
GO:0031985	biolink:NamedThing	Golgi cisterna	Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.	got7fsn_ti	Golgi lamellae											NIF_Subcellular:sao561419532		cellular_component											owl:Class	
GO:0031103	biolink:NamedThing	axon regeneration	The regrowth of axons following their loss or damage.	got7fsn_ti														biological_process											owl:Class	
GO:0061564	biolink:NamedThing	axon development	The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).	got7fsn_ti							dph	2013-07-18T14:43:01Z						biological_process											owl:Class	
GO:0048563	biolink:NamedThing	post-embryonic animal organ morphogenesis	Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti														biological_process											owl:Class	
GO:0016334	biolink:NamedThing	establishment or maintenance of polarity of follicular epithelium	Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.	got7fsn_ti														biological_process											owl:Class	
GO:0071486	biolink:NamedThing	cellular response to high light intensity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.	got7fsn_ti							mah	2009-12-18T02:13:23Z						biological_process											owl:Class	
GO:0071484	biolink:NamedThing	cellular response to light intensity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.	got7fsn_ti							mah	2009-12-18T02:11:03Z						biological_process											owl:Class	
GO:0034947	biolink:NamedThing	terephthalate decarboxylase activity	Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-.	got7fsn_ti												UM-BBD_reactionID:r0321		molecular_function											owl:Class	
GO:1990033	biolink:NamedThing	dendritic branch point	The part of a dendritic tree where it branches, giving rise to a dendritic branch.	got7fsn_ti	branch point of dendrite						pr	2013-02-07T13:01:01Z				NIF_Subcellular:sao1348591767		cellular_component											owl:Class	
GO:0061845	biolink:NamedThing	neuron projection branch point	The location where a secondary projection arises from a neuron projection.	got7fsn_ti														cellular_component											owl:Class	
GO:0090535	biolink:NamedThing	WICH complex	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair.	got7fsn_ti							tb	2013-02-11T14:07:14Z						cellular_component											owl:Class	
GO:0031010	biolink:NamedThing	ISWI-type complex	Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.	got7fsn_ti														cellular_component											owl:Class	
GO:0000776	biolink:NamedThing	kinetochore	A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	got7fsn_ti	condensed chromosome kinetochore|condensed nuclear chromosome kinetochore	https://github.com/geneontology/go-ontology/issues/21126			Note that the kinetochore overlaps the centromeric DNA, but centromeric DNA is not part of the kinetochore.						GO:0000778|GO:0005699|GO:0000777	Wikipedia:Kinetochore		cellular_component											owl:Class	
GO:0051702	biolink:NamedThing	biological process involved in interaction with symbiont	An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.	got7fsn_ti	interaction with symbiont	https://github.com/geneontology/go-ontology/issues/20191												biological_process											owl:Class	
GO:0039513	biolink:NamedThing	suppression by virus of host catalytic activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity.	got7fsn_ti	down-regulation by virus of host enzyme activity|inhibition by virus of host catalytic activity|downregulation by virus of host catalytic activity|negative regulation by virus of host catalytic activity						bf	2011-06-16T02:32:49Z						biological_process											owl:Class	
GO:0039516	biolink:NamedThing	modulation by virus of host catalytic activity	The process in which a virus effects a change in host enzyme activity.	got7fsn_ti	regulation of host catalytic activity by virus|modulation of catalytic activity of host by virus|regulation by virus of host catalytic activity						bf	2011-06-16T02:59:35Z						biological_process											owl:Class	
GO:0070449	biolink:NamedThing	elongin complex	A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits.	got7fsn_ti	transcription factor B (SIII) complex|transcription elongation factor SIII complex|elongin (SIII) complex				See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.									cellular_component											owl:Class	
GO:0102422	biolink:NamedThing	curcumin-4'-O-beta-D-gentiotrioside 1,6-glucosyltransferase activity	Catalysis of the reaction: curcumin 4'-O-beta-D-gentiotrioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotetraside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13814		molecular_function											owl:Class	
GO:1990684	biolink:NamedThing	protein-lipid-RNA complex	A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other.	got7fsn_ti	miRNA-lipoprotein complex				Examples of protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034364 'high-density lipoprotein particle' or GO:0034362 'low-density lipoprotein particle', which describe complexes of proteins and lipids only, without RNAs.		pr	2015-03-11T14:24:33Z						cellular_component											owl:Class	
GO:0140007	biolink:NamedThing	KICSTOR complex	A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2.	got7fsn_ti							pg	2017-03-10T12:47:30Z						cellular_component											owl:Class	
GO:0098750	biolink:NamedThing	FYXD domain binding	Binding to a FXYD domain.	got7fsn_ti														molecular_function											owl:Class	
GO:0000234	biolink:NamedThing	phosphoethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate.	got7fsn_ti	phosphoethanolamine methyltransferase activity|S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity											MetaCyc:2.1.1.103-RXN|RHEA:20365|EC:2.1.1.103|KEGG_REACTION:R02037		molecular_function											owl:Class	
GO:1990655	biolink:NamedThing	4 iron, 3 sulfur cluster binding	Binding to a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria.	got7fsn_ti	4Fe-3S cluster binding						pr	2015-02-24T17:07:23Z						molecular_function											owl:Class	
GO:0051536	biolink:NamedThing	iron-sulfur cluster binding	Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.	got7fsn_ti	Fe/S binding|iron sulfur cluster binding|iron-sulphur cluster binding|iron sulphur cluster binding													molecular_function											owl:Class	
GO:0072181	biolink:NamedThing	mesonephric duct formation	The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.	got7fsn_ti	Wolffian duct formation						mah	2010-02-26T02:38:03Z						biological_process											owl:Class	
GO:0072179	biolink:NamedThing	nephric duct formation	The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.	got7fsn_ti							mah	2010-02-26T02:35:55Z						biological_process											owl:Class	
GO:0005796	biolink:NamedThing	Golgi lumen	The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.	got7fsn_ti														cellular_component											owl:Class	
GO:0000248	biolink:NamedThing	C-5 sterol desaturase activity	Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.	got7fsn_ti	sterol-C5-desaturase activity											Reactome:R-HSA-195664|Reactome:R-HSA-6807053		molecular_function											owl:Class	
GO:0045778	biolink:NamedThing	positive regulation of ossification	Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.	got7fsn_ti	stimulation of ossification|up regulation of ossification|positive regulation of bone biosynthesis|up-regulation of ossification|positive regulation of bone formation|activation of ossification|upregulation of ossification													biological_process											owl:Class	
GO:0002557	biolink:NamedThing	histamine secretion by basophil	The regulated release of histamine by a basophil or group of basophils.	got7fsn_ti														biological_process											owl:Class	
GO:0002441	biolink:NamedThing	histamine secretion involved in inflammatory response	The regulated release of histamine by a cell as part of an inflammatory response.	got7fsn_ti	histamine secretion involved in acute inflammatory response													biological_process											owl:Class	
GO:0060074	biolink:NamedThing	synapse maturation	The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.	got7fsn_ti	synaptic maturation													biological_process											owl:Class	
GO:0042249	biolink:NamedThing	establishment of planar polarity of embryonic epithelium	Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates.	got7fsn_ti														biological_process											owl:Class	
GO:0032033	biolink:NamedThing	myosin II light chain binding	Binding to a light chain of a myosin II complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0032027	biolink:NamedThing	myosin light chain binding	Binding to a light chain of a myosin complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0008918	biolink:NamedThing	lipopolysaccharide 3-alpha-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide.	got7fsn_ti	UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase activity|LPS 3-alpha-galactosyltransferase activity|UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity|lipopolysaccharide galactosyltransferase activity|lipopolysaccharide 1,3-galactosyltransferase activity|UDPgalactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity|UDP-galactose:polysaccharide galactosyltransferase activity|uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase activity|uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase activity|lipopolysaccharide-alpha-1,3-D-galactosyltransferase											EC:2.4.1.44|MetaCyc:2.4.1.44-RXN		molecular_function											owl:Class	
GO:0042113	biolink:NamedThing	B cell activation	The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti	B-cell activation|B-lymphocyte activation|B lymphocyte activation													biological_process											owl:Class	
GO:0050130	biolink:NamedThing	N-methyl-2-oxoglutaramate hydrolase activity	Catalysis of the reaction: N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylammonium.	got7fsn_ti	5-hydroxy-N-methylpyroglutamate synthase activity|N-methyl-2-oxoglutaramate methylamidohydrolase activity											RHEA:24108|EC:3.5.1.36|MetaCyc:N-METHYL-2-OXOGLUTARAMATE-HYDROLASE-RXN|KEGG_REACTION:R01587		molecular_function											owl:Class	
GO:0046871	biolink:NamedThing	N-acetylgalactosamine binding	Binding to N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine.	got7fsn_ti	N-acetylgalactosamine lectin													molecular_function											owl:Class	
GO:0097367	biolink:NamedThing	carbohydrate derivative binding	Binding to a carbohydrate derivative.	got7fsn_ti							pr	2012-08-02T13:03:39Z						molecular_function											owl:Class	
GO:0043005	biolink:NamedThing	neuron projection	A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	got7fsn_ti	neuron process|nerve fiber|neuronal cell projection|neuron protrusion|neurite											NIF_Subcellular:sao867568886		cellular_component											owl:Class	
GO:0097693	biolink:NamedThing	ocelloid	Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids.	got7fsn_ti							pr	2015-11-13T14:27:01Z						cellular_component											owl:Class	
GO:0043229	biolink:NamedThing	intracellular organelle	Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0009715	biolink:NamedThing	chalcone biosynthetic process	The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives.	got7fsn_ti	chalcone synthesis|chalcone biosynthesis|chalcone formation|chalcone anabolism													biological_process											owl:Class	
GO:0009699	biolink:NamedThing	phenylpropanoid biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.	got7fsn_ti	phenylpropanoid formation|phenylpropanoid synthesis|phenylpropanoid anabolism|phenylpropanoid biosynthesis													biological_process											owl:Class	
GO:0001503	biolink:NamedThing	ossification	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.	got7fsn_ti	bone formation|bone biosynthesis|osteogenesis				Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'.							Wikipedia:Ossification		biological_process											owl:Class	
GO:0001114	biolink:NamedThing	protein-DNA-RNA complex	A macromolecular complex containing protein, DNA, and RNA molecules.	got7fsn_ti							krc	2010-12-03T02:09:38Z						cellular_component											owl:Class	
GO:0006192	biolink:NamedThing	IDP phosphorylation	The process of introducing a phosphate group into IDP, inosine (5'-)diphosphate, to produce ITP.	got7fsn_ti														biological_process											owl:Class	
GO:0046707	biolink:NamedThing	IDP metabolic process	The chemical reactions and pathways involving IDP, inosine 5'-diphosphate.	got7fsn_ti	IDP metabolism													biological_process											owl:Class	
GO:0102061	biolink:NamedThing	endo-beta-bergamotene synthase activity	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphoric acid.	got7fsn_ti	endo-beta-bergamontene synthase activity|(2Z,6Z)-farnesyl diphosphate <=> (+)-endo-beta-bergamotene|(+)-endo-beta-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)											MetaCyc:RXN-10483|EC:4.2.3.53|RHEA:30467		molecular_function											owl:Class	
GO:0047836	biolink:NamedThing	D-tryptophan N-malonyltransferase activity	Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H(+).	got7fsn_ti	malonyl-CoA:D-tryptophan N-malonyltransferase activity											EC:2.3.1.112|KEGG_REACTION:R02482|RHEA:23320|MetaCyc:D-TRYPTOPHAN-N-MALONYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0047442	biolink:NamedThing	17-alpha-hydroxyprogesterone aldolase activity	Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione.	got7fsn_ti	17alpha-hydroxyprogesterone acetaldehyde-lyase activity|C-17/C-20 lyase activity|17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming)|17-alpha-hydroxyprogesterone acetaldehyde-lyase activity|17alpha-hydroxyprogesterone aldolase activity											RHEA:14753|EC:4.1.2.30|MetaCyc:4.1.2.30-RXN		molecular_function											owl:Class	
GO:0003410	biolink:NamedThing	anterior rotation of the optic cup	A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis.	got7fsn_ti							dph	2009-12-21T02:49:48Z						biological_process											owl:Class	
GO:0019410	biolink:NamedThing	aerobic respiration, using carbon monoxide as electron donor	The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation.	got7fsn_ti														biological_process											owl:Class	
GO:0009060	biolink:NamedThing	aerobic respiration	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.	got7fsn_ti												Wikipedia:Cellular_respiration#Aerobic_respiration|MetaCyc:PWY-3781		biological_process											owl:Class	
GO:0030336	biolink:NamedThing	negative regulation of cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.	got7fsn_ti	down-regulation of cell migration|inhibition of cell migration|down regulation of cell migration|downregulation of cell migration													biological_process											owl:Class	
GO:0007065	biolink:NamedThing	male meiosis sister chromatid cohesion	The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male.	got7fsn_ti														biological_process											owl:Class	
GO:0051177	biolink:NamedThing	meiotic sister chromatid cohesion	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0045060	biolink:NamedThing	negative thymic T cell selection	The process of elimination of immature T cells in the thymus which react strongly with self-antigens.	got7fsn_ti	negative thymic T-cell selection|negative thymic T lymphocyte selection|negative thymic T-lymphocyte selection													biological_process											owl:Class	
GO:0045061	biolink:NamedThing	thymic T cell selection	The process of T cell selection that occurs in the thymus.	got7fsn_ti	thymic T lymphocyte selection|thymic T-cell selection|thymic T-lymphocyte selection													biological_process											owl:Class	
GO:0051075	biolink:NamedThing	S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity	Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.	got7fsn_ti	S-adenosyl methionine:tRNA ribosyltransferase-isomerase activity											RHEA:32155|EC:2.4.99.17		molecular_function											owl:Class	
GO:0016757	biolink:NamedThing	glycosyltransferase activity	Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).	got7fsn_ti	transglycosylase activity|transferase activity, transferring other glycosyl groups|transferase activity, transferring glycosyl groups|transglycosidase activity										GO:0016932	Reactome:R-HSA-6785565|EC:2.4.-.-|Reactome:R-HSA-5173005		molecular_function											owl:Class	
GO:1900099	biolink:NamedThing	negative regulation of plasma cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation.	got7fsn_ti	downregulation of plasma cell differentiation|inhibition of plasma cell development|downregulation of plasma cell development|down-regulation of plasma cell differentiation|inhibition of plasma cell differentiation|negative regulation of plasma cell development|down-regulation of plasma cell development|down regulation of plasma cell differentiation|down regulation of plasma cell development						bf	2012-02-15T10:46:05Z						biological_process											owl:Class	
GO:0002698	biolink:NamedThing	negative regulation of immune effector process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.	got7fsn_ti	down-regulation of immune effector process|downregulation of immune effector process|inhibition of immune effector process|down regulation of immune effector process													biological_process											owl:Class	
GO:0036382	biolink:NamedThing	flavin reductase (NADH) activity	Catalysis of the reaction: reduced flavin + NAD+ = flavin + NADH + H+.	got7fsn_ti	flavin:NADH oxidoreductase activity|NADH-dependent flavin reductase activity						bf	2013-05-23T11:23:09Z				EC:1.5.1.36|MetaCyc:1.5.1.36-RXN|KEGG_REACTION:R09662|RHEA:31303		molecular_function											owl:Class	
GO:0017045	biolink:NamedThing	corticotropin-releasing hormone activity	The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary.	got7fsn_ti	adrenocorticotropin-releasing hormone											Wikipedia:Corticotropin-releasing_hormone		molecular_function											owl:Class	
GO:0007221	biolink:NamedThing	positive regulation of transcription of Notch receptor target	The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain.	got7fsn_ti	N receptor target transcription factor activation|Notch receptor target transcription factor activation													biological_process											owl:Class	
GO:0045944	biolink:NamedThing	positive regulation of transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter, global|up regulation of transcription from RNA polymerase II promoter|activation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|up-regulation of transcription from RNA polymerase II promoter|upregulation of global transcription from RNA polymerase II promoter|activation of global transcription from RNA polymerase II promoter|upregulation of transcription from RNA polymerase II promoter|positive regulation of transcription from Pol II promoter|stimulation of transcription from RNA polymerase II promoter|positive regulation of global transcription from Pol II promoter|up-regulation of global transcription from RNA polymerase II promoter|up regulation of global transcription from RNA polymerase II promoter|positive regulation of gene-specific transcription from RNA polymerase II promoter|stimulation of global transcription from RNA polymerase II promoter										GO:0010552|GO:0045817			biological_process											owl:Class	
GO:0033889	biolink:NamedThing	N-sulfoglucosamine-3-sulfatase activity	Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.	got7fsn_ti	N-sulfo-3-sulfoglucosamine 3-sulfohydrolase activity|chondroitinsulfatase activity											MetaCyc:3.1.6.15-RXN|EC:3.1.6.15		molecular_function											owl:Class	
GO:0014854	biolink:NamedThing	response to inactivity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0042210	biolink:NamedThing	octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol	The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter.	got7fsn_ti	catabolism of octamethylcyclotetrasiloxane to DMSD|octamethylcyclotetrasiloxane degradation to dimethylsilanediol|octamethylcyclotetrasiloxane breakdown to dimethylsilanediol|catabolic process of octamethylcyclotetrasiloxane to DMSD											UM-BBD_pathwayID:osi		biological_process											owl:Class	
GO:0018947	biolink:NamedThing	anaerobic organosilicon metabolic process	The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen.	got7fsn_ti	anaerobic organosilicone metabolism|anaerobic organosilicone metabolic process|anaerobic organosilicon metabolism											UM-BBD_pathwayID:osi		biological_process											owl:Class	
GO:0046454	biolink:NamedThing	dimethylsilanediol metabolic process	The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.	got7fsn_ti	dimethylsilanediol metabolism													biological_process											owl:Class	
GO:0090613	biolink:NamedThing	5'-deoxyadenosine deaminase activity	Catalysis of the reaction: 5'deoxyadenosine + H2O = 5'deoxyinosine + NH3.	got7fsn_ti							tb	2014-10-23T15:59:38Z				RHEA:42892|EC:3.5.4.41		molecular_function											owl:Class	
GO:0017062	biolink:NamedThing	respiratory chain complex III assembly	The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.	got7fsn_ti	complex III biogenesis|cytochrome bc(1) complex biogenesis|cytochrome bc(1) complex assembly|coenzyme Q and cytochrome c reductase complex biogenesis|complex III assembly|coenzyme Q and cytochrome c reductase complex assembly													biological_process											owl:Class	
GO:0017004	biolink:NamedThing	cytochrome complex assembly	The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.	got7fsn_ti	cytochrome biogenesis													biological_process											owl:Class	
GO:0048208	biolink:NamedThing	COPII vesicle coating	The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.	got7fsn_ti	COPII coating of ER-derived vesicle|COPII vesicle coat assembly|COPII vesicle coat formation													biological_process											owl:Class	
GO:0070333	biolink:NamedThing	alpha6-beta4 integrin-Shc-Grb2 complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2.	got7fsn_ti	ITGA6-ITGB4-SHC-GRB2 complex													cellular_component											owl:Class	
GO:0036506	biolink:NamedThing	maintenance of unfolded protein	Maintaining a protein in an unfolded, soluble state.	got7fsn_ti							bf	2015-06-11T10:17:36Z						biological_process											owl:Class	
GO:0031647	biolink:NamedThing	regulation of protein stability	Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.	got7fsn_ti														biological_process											owl:Class	
GO:0030884	biolink:NamedThing	exogenous lipid antigen binding	Binding to an exogenous lipid antigen (examples include microbial lipids and glycolipids).	got7fsn_ti														molecular_function											owl:Class	
GO:0030882	biolink:NamedThing	lipid antigen binding	Binding to a lipid antigen.	got7fsn_ti														molecular_function											owl:Class	
GO:0070699	biolink:NamedThing	type II activin receptor binding	Binding to a type II activin receptor.	got7fsn_ti							mah	2009-06-04T04:16:26Z						molecular_function											owl:Class	
GO:0070697	biolink:NamedThing	activin receptor binding	Binding to an activin receptor.	got7fsn_ti							mah	2009-06-04T04:02:13Z						molecular_function											owl:Class	
GO:0019100	biolink:NamedThing	male germ-line sex determination	The determination of sex and sexual phenotype in a male organism's germ line.	got7fsn_ti														biological_process											owl:Class	
GO:0030238	biolink:NamedThing	male sex determination	The specification of male sex of an individual organism.	got7fsn_ti														biological_process											owl:Class	
GO:0021944	biolink:NamedThing	neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration	The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration.	got7fsn_ti														biological_process											owl:Class	
GO:0099134	biolink:NamedThing	chimeric sorocarp development	Development of a sorocarp formed by aggregation of cells with different genotypes.	got7fsn_ti														biological_process											owl:Class	
GO:0030587	biolink:NamedThing	sorocarp development	The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	fruiting body development|fruiting body formation|sorocarp biosynthesis|sorocarp formation													biological_process											owl:Class	
GO:0060206	biolink:NamedThing	estrous cycle phase	The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0044848	biolink:NamedThing	biological phase	A distinct period or stage in a biological process or cycle.	got7fsn_ti					Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase.		jl	2014-07-16T13:12:40Z						biological_process											owl:Class	
GO:0044114	biolink:NamedThing	development of symbiont in host	The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	development of symbiont in host intercellular space|development of symbiont in host vascular tissue				This term partially replaces the obsolete term 'growth or development of symbiont in host ; GO:0044412'. See also 'biological process involved in interaction with host ; GO:0051701.		jl	2009-07-30T03:39:25Z			GO:0044122|GO:0044124			biological_process											owl:Class	
GO:0001994	biolink:NamedThing	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure.	got7fsn_ti	norepinephrine-epinephrine vasoconstriction during control of blood pressure|norepinephrine-epinephrine vasoconstriction during blood pressure regulation|noradrenaline-adrenaline vasoconstriction involved in regulation of blood pressure|norepinephrine-epinephrine vasoconstriction during blood pressure control													biological_process											owl:Class	
GO:0005018	biolink:NamedThing	platelet-derived growth factor alpha-receptor activity	Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity.	got7fsn_ti	alphaPDGF receptor activity|PDGF alpha-receptor activity													molecular_function											owl:Class	
GO:0005017	biolink:NamedThing	platelet-derived growth factor-activated receptor activity	Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	PDGFR activity|platelet-derived growth factor receptor activity|PDGF-activated receptor activity|PDGF receptor activity				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand PDGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.									molecular_function											owl:Class	
GO:0072649	biolink:NamedThing	interferon-kappa production	The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IFNK production|IFN-kappa production|interferon-kappa secretion				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072650			biological_process											owl:Class	
GO:0032606	biolink:NamedThing	type I interferon production	The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	type I interferon secretion|interferon type I production|type I interferon biosynthetic process|type I IFN production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072641|GO:0045351			biological_process											owl:Class	
GO:0035567	biolink:NamedThing	non-canonical Wnt signaling pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin.	got7fsn_ti	non-canonical Wnt receptor signaling pathway|beta-catenin-independent Wnt receptor signaling pathway|non-canonical Wnt receptor signalling pathway|non-canonical Wnt-activated signaling pathway				This term should only be used when Wnt receptor signaling occurs via a beta-catenin-independent route but the downstream effectors are unknown. If the downstream effectors are known, consider instead annotating to one of the children, or requesting a new term.		bf	2010-07-23T02:26:01Z						biological_process											owl:Class	
GO:0045302	biolink:NamedThing	choloylglycine hydrolase activity	Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.	got7fsn_ti	3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity|choloyltaurine hydrolase activity|glycocholase activity|bile salt hydrolase activity											RHEA:19353|MetaCyc:CHOLOYLGLYCINE-HYDROLASE-RXN|EC:3.5.1.24		molecular_function											owl:Class	
GO:0015341	biolink:NamedThing	zinc efflux active transmembrane transporter activity	Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force.	got7fsn_ti	zinc efflux permease activity													molecular_function											owl:Class	
GO:0022883	biolink:NamedThing	zinc efflux transmembrane transporter activity	Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	zinc efflux permease activity													molecular_function											owl:Class	
GO:0102614	biolink:NamedThing	germacrene A acid 8beta-hydroxylase activity	Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + NADPH + O2 + H+ <=> 8beta-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15460		molecular_function											owl:Class	
GO:0018217	biolink:NamedThing	peptidyl-aspartic acid phosphorylation	The phosphorylation of peptidyl-aspartic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0018197	biolink:NamedThing	peptidyl-aspartic acid modification	The modification of peptidyl-aspartic acid.	got7fsn_ti														biological_process											owl:Class	
GO:1903053	biolink:NamedThing	regulation of extracellular matrix organization	Any process that modulates the frequency, rate or extent of extracellular matrix organization.	got7fsn_ti	regulation of extracellular matrix organization and biogenesis|regulation of extracellular matrix organisation						rl	2014-05-23T17:15:41Z						biological_process											owl:Class	
GO:0016668	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP.	got7fsn_ti	oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor|oxidoreductase activity, acting on NADH or NADPH, disulphide as acceptor|oxidoreductase activity, acting on sulphur group of donors, NAD or NADP as acceptor|oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor										GO:0016654	EC:1.8.1.-		molecular_function											owl:Class	
GO:0061061	biolink:NamedThing	muscle structure development	The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.	got7fsn_ti							dph	2010-03-09T08:55:14Z						biological_process											owl:Class	
GO:0071881	biolink:NamedThing	adenylate cyclase-inhibiting adrenergic receptor signaling pathway	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	got7fsn_ti	adrenergic receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by adrenergic receptor signalling pathway|inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway|adrenergic receptor, adenylate cyclase inhibiting pathway						mah	2010-09-13T04:22:53Z						biological_process											owl:Class	
GO:0048700	biolink:NamedThing	acquisition of desiccation tolerance in seed	The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state.	got7fsn_ti	acquisition of desiccation tolerance													biological_process											owl:Class	
GO:0097439	biolink:NamedThing	acquisition of desiccation tolerance	The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state.	got7fsn_ti							pr	2012-12-05T15:09:52Z						biological_process											owl:Class	
GO:0008673	biolink:NamedThing	2-dehydro-3-deoxygluconokinase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H(+).	got7fsn_ti	ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase activity|2-keto-3-deoxygluconokinase activity|KDG kinase activity|2-keto-3-deoxy-D-gluconic acid kinase activity|2-keto-3-deoxygluconate kinase activity|3-deoxy-2-oxo-D-gluconate kinase activity|ketodeoxygluconokinase activity|2-keto-3-deoxygluconokinase (phosphorylating)											KEGG_REACTION:R01541|MetaCyc:DEOXYGLUCONOKIN-RXN|EC:2.7.1.45|RHEA:14797		molecular_function											owl:Class	
GO:0071493	biolink:NamedThing	cellular response to UV-B	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.	got7fsn_ti	cellular response to UVB light stimulus|cellular response to UV-B light stimulus|cellular response to medium wave ultraviolet radiation stimulus|cellular response to UV-B radiation stimulus|cellular response to UVB radiation stimulus|cellular response to medium wave ultraviolet light stimulus						mah	2009-12-18T02:21:56Z						biological_process											owl:Class	
GO:0080171	biolink:NamedThing	lytic vacuole organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.	got7fsn_ti	lytic vacuole biogenesis|lytic vacuole organization and biogenesis|lytic vacuole organisation|lytic vacuolar assembly						dhl	2011-04-25T04:40:46Z						biological_process											owl:Class	
GO:0065007	biolink:NamedThing	biological regulation	Any process that modulates a measurable attribute of any biological process, quality or function.	got7fsn_ti	regulation													biological_process											owl:Class	
GO:0120306	biolink:NamedThing	cellular response to actin cytoskeletal stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton.	got7fsn_ti	cellular response to latrunculin B|cellular response to actin cytoskeleton stress|response to latrunculin A|response to latrunculin B|cellular response to latrunculin A	https://github.com/geneontology/go-ontology/issues/20189					krc	2021-02-12T21:44:37Z			GO:1904805|GO:1903956|GO:1904804|GO:1903957			biological_process											owl:Class	
GO:0071565	biolink:NamedThing	nBAF complex	A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.	got7fsn_ti							mah	2010-01-20T03:41:19Z						cellular_component											owl:Class	
GO:0016298	biolink:NamedThing	lipase activity	Catalysis of the hydrolysis of a lipid or phospholipid.	got7fsn_ti												EC:3.1.1.-|Reactome:R-HSA-163402|Reactome:R-HSA-163432		molecular_function											owl:Class	
GO:0097395	biolink:NamedThing	response to interleukin-32	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.	got7fsn_ti	response to IL-32						pr	2012-10-23T13:21:16Z						biological_process											owl:Class	
GO:0010588	biolink:NamedThing	cotyledon vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants.	got7fsn_ti														biological_process											owl:Class	
GO:0010051	biolink:NamedThing	xylem and phloem pattern formation	The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	vascular tissue pattern formation													biological_process											owl:Class	
GO:0061368	biolink:NamedThing	behavioral response to formalin induced pain	Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.	got7fsn_ti							dph	2010-10-21T03:29:48Z						biological_process											owl:Class	
GO:0098874	biolink:NamedThing	spike train	A series of sequential, propagated action potentials occurring in a single cell.	got7fsn_ti	spike-train|burst of action potentials										GO:0099603			biological_process											owl:Class	
GO:0035965	biolink:NamedThing	cardiolipin acyl-chain remodeling	Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.	got7fsn_ti	cardiolipin maturation|cardiolipin acyl-chain remodelling|diphosphatidylglycerol remodeling						bf	2011-08-03T11:17:49Z						biological_process											owl:Class	
GO:0032048	biolink:NamedThing	cardiolipin metabolic process	The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.	got7fsn_ti	diphosphatidylglycerol metabolism|diphosphatidylglycerol metabolic process|cardiolipin metabolism													biological_process											owl:Class	
GO:0004486	biolink:NamedThing	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+.	got7fsn_ti	5,10-methylene-THF dehydrogenase activity|N5,N10-methylenetetrahydrofolate dehydrogenase activity											EC:1.5.1.5|Reactome:R-HSA-200644|Reactome:R-HSA-200718		molecular_function											owl:Class	
GO:0010304	biolink:NamedThing	PSII associated light-harvesting complex II catabolic process	The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.	got7fsn_ti	LHCII catabolism													biological_process											owl:Class	
GO:0030754	biolink:NamedThing	apigenin 4'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone.	got7fsn_ti	flavonoid methyltransferase activity|S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase activity|flavonoid O-methyltransferase activity											RHEA:20429|MetaCyc:APIGENIN-4-O-METHYLTRANSFERASE-RXN|EC:2.1.1.75		molecular_function											owl:Class	
GO:0034501	biolink:NamedThing	protein localization to kinetochore	Any process in which a protein is transported to, or maintained at, the kinetochore.	got7fsn_ti	protein localisation to kinetochore|condensin localization to kinetochore													biological_process											owl:Class	
GO:0034502	biolink:NamedThing	protein localization to chromosome	Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.	got7fsn_ti	condensin localization to chromosome|protein localisation to chromosome													biological_process											owl:Class	
GO:0031728	biolink:NamedThing	CCR3 chemokine receptor binding	Binding to a CCR3 chemokine receptor.	got7fsn_ti	CCR3 chemokine receptor ligand|eosinophil eotaxin receptor binding													molecular_function											owl:Class	
GO:0071785	biolink:NamedThing	endoplasmic reticulum cisternal network maintenance	The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.	got7fsn_ti	ER cisternal network maintenance						mah	2010-09-01T01:52:26Z						biological_process											owl:Class	
GO:0071783	biolink:NamedThing	endoplasmic reticulum cisternal network organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.	got7fsn_ti	ER cisternal network organization|ER cisternal network organisation|endoplasmic reticulum cisternal network organisation						mah	2010-09-01T01:47:28Z						biological_process											owl:Class	
GO:0034821	biolink:NamedThing	citronellol dehydrogenase activity	Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r1155		molecular_function											owl:Class	
GO:0048439	biolink:NamedThing	flower morphogenesis	The process in which the anatomical structures of the flower are generated and organized.	got7fsn_ti											GO:0048411			biological_process											owl:Class	
GO:1902929	biolink:NamedThing	plasma membrane of growing cell tip	Any plasma membrane part that is part of a growing cell tip.	got7fsn_ti	plasma membrane part of growing cell tip|growing cell tip plasma membrane part|plasma membrane part of growing cell end						mah	2014-04-22T16:02:06Z						cellular_component											owl:Class	
GO:0031520	biolink:NamedThing	plasma membrane of cell tip	The portion of the plasma membrane surrounding the cell tip.	got7fsn_ti	'plasma membrane, cell tip'													cellular_component											owl:Class	
GO:1990248	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to DNA damage	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage.	got7fsn_ti							pg	2013-12-04T13:28:04Z						biological_process											owl:Class	
GO:0052593	biolink:NamedThing	tryptamine:oxygen oxidoreductase (deaminating) activity	Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+.	got7fsn_ti												KEGG_REACTION:R02173|EC:1.4.3.21|MetaCyc:RXN-1401		molecular_function											owl:Class	
GO:0044465	biolink:NamedThing	modulation of sensory perception of pain in other organism	A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism.	got7fsn_ti	regulation of sensory perception of pain in another organism						jl	2012-01-12T03:14:19Z						biological_process											owl:Class	
GO:0034861	biolink:NamedThing	benzothiazole-2-sulfonate hydrolase activity	Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-.	got7fsn_ti												UM-BBD_reactionID:r1290|EC:3.13.1.-		molecular_function											owl:Class	
GO:0046508	biolink:NamedThing	hydrolase activity, acting on carbon-sulfur bonds	Catalysis of the hydrolysis of any carbon-sulfur bond, C-S.	got7fsn_ti	hydrolase activity, acting on carbon-sulphur bonds											EC:3.13.-.-		molecular_function											owl:Class	
GO:0034794	biolink:NamedThing	cyclopropanecarboxyl-CoA decyclase activity	Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA.	got7fsn_ti												EC:5.5.1.-|UM-BBD_reactionID:r1057		molecular_function											owl:Class	
GO:0016872	biolink:NamedThing	intramolecular lyase activity	The catalysis of certain rearrangements of a molecule to break or form a ring.	got7fsn_ti												EC:5.5.1.-		molecular_function											owl:Class	
GO:0016132	biolink:NamedThing	brassinosteroid biosynthetic process	The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.	got7fsn_ti	brassinosteroid anabolism|brassinosteroid formation|brassinosteroid synthesis|brassinosteroid biosynthesis											MetaCyc:PWY-699|MetaCyc:PWY-2582		biological_process											owl:Class	
GO:0042446	biolink:NamedThing	hormone biosynthetic process	The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.	got7fsn_ti	hormone anabolism|hormone biosynthesis|hormone synthesis|hormone formation													biological_process											owl:Class	
GO:0034059	biolink:NamedThing	response to anoxia	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.	got7fsn_ti	response to anoxic stress				Note that this term should not be confused with 'response to hypoxia ; GO:0001666'.									biological_process											owl:Class	
GO:0018258	biolink:NamedThing	protein O-linked glycosylation via hydroxyproline	The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.	got7fsn_ti	protein amino acid O-linked glycosylation via hydroxyproline											RESID:AA0212		biological_process											owl:Class	
GO:0045332	biolink:NamedThing	phospholipid translocation	The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.	got7fsn_ti	flippase|phospholipid scrambling				Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.									biological_process											owl:Class	
GO:0097035	biolink:NamedThing	regulation of membrane lipid distribution	Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane.	got7fsn_ti							pr	2011-04-08T02:01:19Z						biological_process											owl:Class	
GO:0047636	biolink:NamedThing	alanopine dehydrogenase activity	Catalysis of the reaction: 2,2'-iminodipropanoate + H(2)O + NAD(+) = L-alanine + H(+) + NADH + pyruvate.	got7fsn_ti	alanopine:NAD oxidoreductase activity|ADH|2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming)|alanopine: NAD oxidoreductase activity|alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase activity|meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase activity|ALPDH											MetaCyc:ALANOPINE-DEHYDROGENASE-RXN|RHEA:17589|KEGG_REACTION:R00398|EC:1.5.1.17		molecular_function											owl:Class	
GO:0033823	biolink:NamedThing	procollagen glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen.	got7fsn_ti	collagen glucosyltransferase activity|UDP-glucose-collagenglucosyltransferase activity|collagen hydroxylysyl glucosyltransferase activity|uridine diphosphoglucose-collagen glucosyltransferase activity|galactosylhydroxylysyl glucosyltransferase activity|galactosylhydroxylysine glucosyltransferase activity|galactosylhydroxylysine-glucosyltransferase activity|UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity|UDPglucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity											Reactome:R-HSA-1981157|MetaCyc:PROCOLLAGEN-GLUCOSYLTRANSFERASE-RXN|RHEA:12576|EC:2.4.1.66		molecular_function											owl:Class	
GO:1990477	biolink:NamedThing	MTREC complex	Protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as RNA silencing (NURS) complex.	got7fsn_ti	Mtl1-Red1 core complex|PAXT complex|NURS complex	https://github.com/geneontology/go-ontology/issues/21207|https://github.com/geneontology/go-ontology/issues/19059			An example of this is the complex formed by Red1 and Mtl1 in S. pombe (UniProt symbols Q9UTR8 and O13799 respectively) in PMID:24210919 (inferred from direct assay).		mah	2014-03-24T13:30:52Z			GO:1990345			cellular_component											owl:Class	
GO:0047401	biolink:NamedThing	trithionate hydrolase activity	Catalysis of the reaction: H(2)O + trithionate = H(+) + sulfate + thiosulfate.	got7fsn_ti	trithionate thiosulfohydrolase activity											MetaCyc:3.12.1.1-RXN|EC:3.12.1.1|RHEA:21884|KEGG_REACTION:R01930		molecular_function											owl:Class	
GO:0016828	biolink:NamedThing	hydrolase activity, acting on acid sulfur-sulfur bonds	Catalysis of the hydrolysis of any acid sulfur-sulfur bond.	got7fsn_ti	hydrolase activity, acting on acid sulphur-sulphur bonds											EC:3.12.-.-		molecular_function											owl:Class	
GO:0007391	biolink:NamedThing	dorsal closure	The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.	got7fsn_ti														biological_process											owl:Class	
GO:0035588	biolink:NamedThing	G protein-coupled purinergic receptor signaling pathway	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.	got7fsn_ti	G-protein coupled purinergic receptor signaling pathway|G-protein coupled purinergic receptor signalling pathway						bf	2010-10-22T11:11:53Z						biological_process											owl:Class	
GO:0030506	biolink:NamedThing	ankyrin binding	Binding to ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.	got7fsn_ti														molecular_function											owl:Class	
GO:0060006	biolink:NamedThing	angular vestibuloocular reflex	A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.	got7fsn_ti														biological_process											owl:Class	
GO:0021872	biolink:NamedThing	forebrain generation of neurons	The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.	got7fsn_ti	generation of neurons in forebrain													biological_process											owl:Class	
GO:0048699	biolink:NamedThing	generation of neurons	The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.	got7fsn_ti	neuron generation													biological_process											owl:Class	
GO:0016257	biolink:NamedThing	N-glycan processing to secreted and cell-surface N-glycans	The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus.	got7fsn_ti														biological_process											owl:Class	
GO:0089701	biolink:NamedThing	U2AF complex	A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point.	got7fsn_ti	U2 accessory factor|U2AF													cellular_component											owl:Class	
GO:0120092	biolink:NamedThing	crotonyl-CoA hydratase activity	Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.	got7fsn_ti							krc	2017-08-22T20:13:55Z				RHEA:45584		molecular_function											owl:Class	
GO:0008984	biolink:NamedThing	protein-glutamate methylesterase activity	Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol.	got7fsn_ti	methylesterase CheB activity|protein-L-glutamate-O5-methyl-ester acylhydrolase activity|protein-L-glutamate-5-O-methyl-ester acylhydrolase activity|CheB methylesterase activity|methyl-accepting chemotaxis protein methyl-esterase activity|chemotaxis-specific methylesterase activity											MetaCyc:MCPMETEST-RXN|EC:3.1.1.61|RHEA:23236|RESID:AA0072		molecular_function											owl:Class	
GO:0070046	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-3 complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).	got7fsn_ti	Stx3-Snap25-Vamp2 complex|SNARE complex (Stx3, Snap25, Vamp2)													cellular_component											owl:Class	
GO:0033937	biolink:NamedThing	3-deoxy-2-octulosonidase activity	Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.	got7fsn_ti	octulosylono hydrolase activity|capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase activity|octulofuranosylono hydrolase activity|2-keto-3-deoxyoctonate hydrolase activity|octulopyranosylonohydrolase activity											EC:3.2.1.124|MetaCyc:3.2.1.124-RXN		molecular_function											owl:Class	
GO:0102905	biolink:NamedThing	valencene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (+)-valencene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8608|RHEA:29511|EC:4.2.3.73		molecular_function											owl:Class	
GO:0070392	biolink:NamedThing	detection of lipoteichoic acid	The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	got7fsn_ti	detection of LTA													biological_process											owl:Class	
GO:0032490	biolink:NamedThing	detection of molecule of bacterial origin	The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal.	got7fsn_ti	detection of bacterium associated molecule|detection of bacterial associated molecule|detection of bacteria associated molecule													biological_process											owl:Class	
GO:0009880	biolink:NamedThing	embryonic pattern specification	The process that results in the patterns of cell differentiation that will arise in an embryo.	got7fsn_ti	embryonic pattern biosynthesis|embryonic pattern formation|ventral/lateral system													biological_process											owl:Class	
GO:0007389	biolink:NamedThing	pattern specification process	Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.	got7fsn_ti	pattern formation|pattern biosynthesis													biological_process											owl:Class	
GO:0140463	biolink:NamedThing	chromatin-protein adaptor	The binding activity of a molecule that brings together a protein or a protein complex with a nucleosome, to establish or maintain the chromatin localization of the protein, or protein complex.	got7fsn_ti	chromatin adaptor|chromatin adaptor activity|chromatin recruitment|chromatin receptor|protein-chromatin adaptor activity	https://github.com/geneontology/go-ontology/issues/17064					pg	2020-05-08T12:31:39Z						molecular_function											owl:Class	
GO:0051737	biolink:NamedThing	GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA.	got7fsn_ti	GTP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity|GTP-dependent polydeoxyribonucleotide kinase activity|GTP-dependent DNA 5'-hydroxyl-kinase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP-dependent DNA kinase activity													molecular_function											owl:Class	
GO:0051733	biolink:NamedThing	polydeoxyribonucleotide kinase activity	Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA.	got7fsn_ti	DNA kinase activity|DNA 5'-hydroxyl kinase activity													molecular_function											owl:Class	
GO:0051110	biolink:NamedThing	peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine	The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).	got7fsn_ti												RESID:AA0372		biological_process											owl:Class	
GO:0051114	biolink:NamedThing	peptidyl-histidine uridylylation	The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine).	got7fsn_ti												RESID:AA0372		biological_process											owl:Class	
GO:0035570	biolink:NamedThing	N-terminal peptidyl-serine methylation	The methylation of the N-terminal serine of proteins.	got7fsn_ti							bf	2010-08-06T01:58:11Z						biological_process											owl:Class	
GO:0014850	biolink:NamedThing	response to muscle activity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0014823	biolink:NamedThing	response to activity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.	got7fsn_ti	response to exercise													biological_process											owl:Class	
GO:0034074	biolink:NamedThing	marneral synthase activity	Catalysis of the reaction: oxidosqualene = marneral.	got7fsn_ti												MetaCyc:RXN-9664|RHEA:31875		molecular_function											owl:Class	
GO:0031559	biolink:NamedThing	oxidosqualene cyclase activity	Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.	got7fsn_ti	2,3-oxidosqualene cyclase activity				Note that the phrase 'oxidosqualene cyclase' has been used to refer to enzymes that catalyze the reaction represented by 'lanosterol synthase activity ; GO:0000250'.									molecular_function											owl:Class	
GO:0018654	biolink:NamedThing	2-hydroxy-phenylacetate hydroxylase activity	Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate.	got7fsn_ti												UM-BBD_reactionID:r0252|EC:1.14.13.-		molecular_function											owl:Class	
GO:0044175	biolink:NamedThing	host cell endosome membrane	The lipid bilayer surrounding a host cell endosome.	got7fsn_ti	host endosome membrane						jl	2009-09-04T03:04:04Z						cellular_component											owl:Class	
GO:0102163	biolink:NamedThing	3-hydroxyacyl-CoA-acyl carrier protein transferase activity	Catalysis of the reaction: coenzyme A + a (3R)-3-hydroxyacyl-[acyl-carrier protein] = a (3R)-3-hydroxyacyl-CoA + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-11785		molecular_function											owl:Class	
GO:0010668	biolink:NamedThing	ectodermal cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0060977	biolink:NamedThing	coronary vasculature morphogenesis	The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.	got7fsn_ti	cardiac vasculature morphogenesis|cardiac blood vessel morphogenesis|heart vasculature morphogenesis|coronary blood vessel morphogenesis|heart blood vessel morphogenesis						dph	2009-10-06T12:28:23Z						biological_process											owl:Class	
GO:0048514	biolink:NamedThing	blood vessel morphogenesis	The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.	got7fsn_ti														biological_process											owl:Class	
GO:0097578	biolink:NamedThing	sequestering of copper ion	The process of binding or confining copper ions such that they are separated from other components of a biological system.	got7fsn_ti	copper ion retention|copper ion storage|sequestration of copper ion|copper ion sequestration|retention of copper ion|storage of copper ion|copper ion sequestering						pr	2014-02-28T11:15:02Z						biological_process											owl:Class	
GO:0006878	biolink:NamedThing	cellular copper ion homeostasis	Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.	got7fsn_ti	copper homeostasis													biological_process											owl:Class	
GO:0004367	biolink:NamedThing	glycerol-3-phosphate dehydrogenase [NAD+] activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.	got7fsn_ti	NAD-alpha-glycerophosphate dehydrogenase activity|hydroglycerophosphate dehydrogenase activity|L-glycerol phosphate dehydrogenase activity|alpha-glycerol phosphate dehydrogenase (NAD) activity|L-alpha-glycerophosphate dehydrogenase activity|alpha-glycerophosphate dehydrogenase (NAD) activity|NADH-dihydroxyacetone phosphate reductase activity|glycerol phosphate dehydrogenase (NAD) activity|L-glycerophosphate dehydrogenase activity|NAD-L-glycerol-3-phosphate dehydrogenase activity|glycerol-3-phosphate dehydrogenase (NAD) activity|L-alpha-glycerol phosphate dehydrogenase activity|NAD-linked glycerol 3-phosphate dehydrogenase activity|NAD-dependent glycerol-3-phosphate dehydrogenase activity|glycerol 1-phosphate dehydrogenase activity|NAD-dependent glycerol phosphate dehydrogenase activity|glycerophosphate dehydrogenase (NAD) activity											EC:1.1.1.8|MetaCyc:1.1.1.8-RXN|KEGG_REACTION:R00842|RHEA:11092|Reactome:R-HSA-75889		molecular_function											owl:Class	
GO:0047952	biolink:NamedThing	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+.	got7fsn_ti	L-glycerol-3-phosphate:NAD(P) oxidoreductase activity|sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase activity|glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) activity|glycerol-3-phosphate dehydrogenase (NAD(P)+) activity						bf	2013-09-30T10:37:46Z			GO:0036439	KEGG_REACTION:R00844|MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN|EC:1.1.1.94		molecular_function											owl:Class	
GO:0034011	biolink:NamedThing	L-cysteate sulfo-lyase activity	Catalysis of the reaction: L-cysteate + H(2)O = NH(4)(+) + pyruvate + sulfite.	got7fsn_ti	L-cysteate bisulfite-lyase (deaminating; pyruvate-forming) activity|CuyA|L-cysteate sulfo-lyase (deaminating) activity											RHEA:13441|MetaCyc:4.4.1.25-RXN|KEGG_REACTION:R07634|EC:4.4.1.25		molecular_function											owl:Class	
GO:0120054	biolink:NamedThing	intestinal motility	Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth).	got7fsn_ti							krc	2017-06-13T20:42:24Z						biological_process											owl:Class	
GO:0046899	biolink:NamedThing	nucleoside triphosphate adenylate kinase activity	Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.	got7fsn_ti	nucleoside-triphosphate-adenylate kinase activity|isozyme 3 of adenylate kinase activity|nucleoside-triphosphate:AMP phosphotransferase activity|GTP:AMP phosphotransferase|guanosine triphosphate-adenylate kinase|nucleoside triphosphate-adenosine monophosphate transphosphorylase activity											EC:2.7.4.10|MetaCyc:2.7.4.10-RXN|Reactome:R-HSA-1008248|RHEA:13749		molecular_function											owl:Class	
GO:0031917	biolink:NamedThing	negative regulation of synaptic metaplasticity	A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.	got7fsn_ti	inhibition of synaptic metaplasticity|down regulation of synaptic metaplasticity|downregulation of synaptic metaplasticity|down-regulation of synaptic metaplasticity													biological_process											owl:Class	
GO:0031914	biolink:NamedThing	negative regulation of synaptic plasticity	A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	got7fsn_ti	inhibition of synaptic plasticity|down-regulation of synaptic plasticity|downregulation of synaptic plasticity|down regulation of synaptic plasticity													biological_process											owl:Class	
GO:0080188	biolink:NamedThing	gene silencing by RNA-directed DNA methylation	A small RNA-based epigenetic gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci. Transposable elements are silenced by this mechanism.	got7fsn_ti	RNA-directed DNA methylation|RdDM	https://github.com/geneontology/go-ontology/issues/19328|https://github.com/geneontology/go-ontology/issues/22047			This process has been shown in plants and in yeasts, but so far has not been detected in vertebrates, organisms that lack RNA-dependent RNA polymerase.		dhl	2012-05-22T02:22:50Z						biological_process											owl:Class	
GO:0005801	biolink:NamedThing	cis-Golgi network	The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.	got7fsn_ti	cis Golgi network|Golgi cis face|forming face|cis face|Golgi cis-face				The CGN is not considered part of the Golgi apparatus but is a separate organelle.							NIF_Subcellular:sao632188024		cellular_component											owl:Class	
GO:1990475	biolink:NamedThing	synaptic vesicle, recycling pool	A synaptic vesicle belonging to the pool that repopulate vacancies within the readily releasable pool (RRP) of synaptic vesicles, and require more significant stimuli than the RRP in order to release neurotransmitter; about 10-15% of the total number of synaptic vesicles at a resting terminal bouton are in this state.	got7fsn_ti	recycling pool of synaptic vesicles						pr	2014-09-02T09:08:22Z						cellular_component											owl:Class	
GO:0008021	biolink:NamedThing	synaptic vesicle	A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.	got7fsn_ti	docked vesicle				This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.							Wikipedia:Synaptic_vesicle|NIF_Subcellular:sao1071221672		cellular_component											owl:Class	
GO:0106124	biolink:NamedThing	reservosome lumen	The volume enclosed by the membranes of a reservosome.	got7fsn_ti							hjd	2018-05-03T17:54:46Z						cellular_component											owl:Class	
GO:0019243	biolink:NamedThing	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.	got7fsn_ti	methylglyoxal breakdown to D-lactate|glyoxalase system|D-lactate biosynthetic process from methylglyoxal|methylglyoxal detoxification|methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione|D-lactate biosynthesis from methylglyoxal|methylglyoxal degradation to D-lactate											MetaCyc:PWY-5386		biological_process											owl:Class	
GO:0061727	biolink:NamedThing	methylglyoxal catabolic process to lactate	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate.	got7fsn_ti							dph	2015-07-21T17:25:57Z						biological_process											owl:Class	
GO:0048876	biolink:NamedThing	chemical homeostasis within retina	Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the retina.	got7fsn_ti														biological_process											owl:Class	
GO:0001895	biolink:NamedThing	retina homeostasis	A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.	got7fsn_ti														biological_process											owl:Class	
GO:0003067	biolink:NamedThing	circadian regulation of systemic arterial blood pressure by hormone	The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.	got7fsn_ti														biological_process											owl:Class	
GO:0048445	biolink:NamedThing	carpel morphogenesis	The process in which the anatomical structures of the carpel are generated and organized.	got7fsn_ti											GO:0048430			biological_process											owl:Class	
GO:0031424	biolink:NamedThing	keratinization	The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.	got7fsn_ti														biological_process											owl:Class	
GO:0085029	biolink:NamedThing	extracellular matrix assembly	The aggregation, arrangement and bonding together of the extracellular matrix.	got7fsn_ti							jl	2010-07-14T12:52:49Z						biological_process											owl:Class	
GO:0030198	biolink:NamedThing	extracellular matrix organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.	got7fsn_ti	extracellular matrix organisation|extracellular matrix organization and biogenesis													biological_process											owl:Class	
GO:1990937	biolink:NamedThing	xylan acetylation	The addition of one or more acetyl groups to a xylan molecule.	got7fsn_ti							tb	2016-03-30T22:10:22Z						biological_process											owl:Class	
GO:0045491	biolink:NamedThing	xylan metabolic process	The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone.	got7fsn_ti	xylan metabolism													biological_process											owl:Class	
GO:0048626	biolink:NamedThing	myoblast fate specification	The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0035667	biolink:NamedThing	TRIF-dependent toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	got7fsn_ti	Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR4 signaling pathway|TRIF-dependent TLR4 signaling pathway|TRIF-dependent toll-like receptor 4 signalling pathway						bf	2011-02-01T02:37:25Z						biological_process											owl:Class	
GO:0050116	biolink:NamedThing	N,N-dimethylformamidase activity	Catalysis of the reaction: N,N-dimethylformamide + H(2)O = dimethylamine + formate.	got7fsn_ti	dimethylformamidase activity|N,N-dimethylformamide amidohydrolase activity|DMFase activity											KEGG_REACTION:R02509|RHEA:19517|MetaCyc:NN-DIMETHYLFORMAMIDASE-RXN|EC:3.5.1.56		molecular_function											owl:Class	
GO:0102393	biolink:NamedThing	decanoyl-[acp] 2-dehydrogenase activity	Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein <=> FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF.	got7fsn_ti												MetaCyc:RXN-13624		molecular_function											owl:Class	
GO:0052890	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin.	got7fsn_ti												EC:1.3.8.-		molecular_function											owl:Class	
GO:0043822	biolink:NamedThing	ribonuclease M5 activity	Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.	got7fsn_ti	5S ribosomal RNA maturation endonuclease activity|RNase M5 activity|5S ribosomal maturation nuclease activity											EC:3.1.26.8|MetaCyc:3.1.26.8-RXN		molecular_function											owl:Class	
GO:0060306	biolink:NamedThing	regulation of membrane repolarization	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.	got7fsn_ti														biological_process											owl:Class	
GO:0017131	biolink:NamedThing	uridine-rich cytoplasmic polyadenylylation element binding	Binding to a U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.	got7fsn_ti	uridine-rich cytoplasmic polyadenylation element binding|U-rich CPE binding													molecular_function											owl:Class	
GO:0008187	biolink:NamedThing	poly-pyrimidine tract binding	Binding to a stretch of pyrimidines (cytosine or uracil) in an RNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:1900575	biolink:NamedThing	emodin biosynthetic process	The chemical reactions and pathways resulting in the formation of emodin.	got7fsn_ti	emodin synthesis|emodin formation|emodin anabolism|emodin biosynthesis						di	2012-05-15T06:42:14Z						biological_process											owl:Class	
GO:0060438	biolink:NamedThing	trachea development	The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.	got7fsn_ti														biological_process											owl:Class	
GO:0031530	biolink:NamedThing	gonadotropin-releasing hormone receptor binding	Binding to a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.	got7fsn_ti	gonadotrophin-releasing hormone receptor binding|GnRH receptor binding													molecular_function											owl:Class	
GO:0051428	biolink:NamedThing	peptide hormone receptor binding	Binding to a receptor for a peptide hormone.	got7fsn_ti	polypeptide hormone receptor binding													molecular_function											owl:Class	
GO:0047439	biolink:NamedThing	3-deoxy-D-manno-octulosonate aldolase activity	Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.	got7fsn_ti	3-deoxy-D-manno-octulosonate D-arabinose-lyase activity|KDOaldolase activity|3-deoxy-D-manno-octulosonic aldolase activity|3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming)|3-deoxyoctulosonic aldolase activity|2-keto-3-deoxyoctonic aldolase activity|2-keto-3-deoxyoctonate aldolase activity											MetaCyc:4.1.2.23-RXN|KEGG_REACTION:R01576|EC:4.1.2.23|RHEA:23340		molecular_function											owl:Class	
GO:0019681	biolink:NamedThing	acetyl-CoA assimilation pathway	The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell.	got7fsn_ti	acetyl-CoA catabolism to alpha-ketoglutarate|acetyl-CoA catabolic process to alpha-oxoglutarate|acetyl-CoA catabolism to alpha-oxoglutarate|acetyl-CoA catabolism to 2-ketoglutarate|acetyl-CoA catabolism to 2-oxoglutarate|acetyl-CoA catabolic process to 2-oxoglutarate|acetyl-CoA catabolic process to alpha-ketoglutarate|acetyl-CoA catabolic process to 2-ketoglutarate													biological_process											owl:Class	
GO:0006103	biolink:NamedThing	2-oxoglutarate metabolic process	The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.	got7fsn_ti	alpha-oxoglutarate metabolism|2-ketoglutarate metabolism|2-oxoglutarate metabolism|alpha-ketoglutarate metabolism|alpha-ketoglutarate metabolic process|alpha-oxoglutarate metabolic process|2-ketoglutarate metabolic process													biological_process											owl:Class	
GO:0080176	biolink:NamedThing	xyloglucan 1,6-alpha-xylosidase activity	Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus.	got7fsn_ti							dhl	2011-04-28T04:08:39Z						molecular_function											owl:Class	
GO:0090559	biolink:NamedThing	regulation of membrane permeability	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.	got7fsn_ti							tb	2014-03-27T13:48:35Z						biological_process											owl:Class	
GO:0044057	biolink:NamedThing	regulation of system process	Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.	got7fsn_ti														biological_process											owl:Class	
GO:0071955	biolink:NamedThing	recycling endosome to Golgi transport	The directed movement of substances from recycling endosomes to the Golgi.	got7fsn_ti							mah	2010-10-08T01:19:00Z						biological_process											owl:Class	
GO:0042147	biolink:NamedThing	retrograde transport, endosome to Golgi	The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.	got7fsn_ti	retrograde (endosome to Golgi) transport													biological_process											owl:Class	
GO:0006571	biolink:NamedThing	tyrosine biosynthetic process	The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.	got7fsn_ti	tyrosine anabolism|tyrosine formation|tyrosine synthesis|tyrosine biosynthesis	https://github.com/geneontology/go-ontology/issues/20583												biological_process											owl:Class	
GO:0009095	biolink:NamedThing	aromatic amino acid family biosynthetic process, prephenate pathway	The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate.	got7fsn_ti	aromatic amino acid family formation, prephenate pathway|aromatic amino acid family biosynthetic process via prephenate|aromatic amino acid family anabolism, prephenate pathway|aromatic amino acid family biosynthetic process via prephenate(2-)|aromatic amino acid family synthesis, prephenate pathway													biological_process											owl:Class	
GO:0052908	biolink:NamedThing	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity	Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA.	got7fsn_ti	S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase activity	https://github.com/geneontology/go-ontology/issues/14459										EC:2.1.1.182|RHEA:19609|MetaCyc:RXN-11633		molecular_function											owl:Class	
GO:0060983	biolink:NamedThing	epicardium-derived cardiac vascular smooth muscle cell differentiation	The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.	got7fsn_ti							dph	2009-10-06T03:05:33Z						biological_process											owl:Class	
GO:0060947	biolink:NamedThing	cardiac vascular smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.	got7fsn_ti	heart vascular smooth muscle cell differentiation						dph	2009-09-29T02:56:08Z						biological_process											owl:Class	
GO:0102767	biolink:NamedThing	flavanone 4'-O-methyltransferase activity	Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine  = 2 H+ + ponciretin + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.231|MetaCyc:RXN-7777|RHEA:31743		molecular_function											owl:Class	
GO:0071985	biolink:NamedThing	multivesicular body sorting pathway	A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded.	got7fsn_ti							mah	2010-10-22T12:04:16Z						biological_process											owl:Class	
GO:0015549	biolink:NamedThing	carbonyl cyanide m-chlorophenylhydrazone transmembrane transporter activity	Enables the transfer of carbonyl cyanide m-chlorophenylhydrazone from one side of a membrane to the other. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.	got7fsn_ti	carbonyl cyanide m-chlorophenylhydrazone transporter activity|CCCP transporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0034789	biolink:NamedThing	2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+.	got7fsn_ti												UM-BBD_reactionID:r1042		molecular_function											owl:Class	
GO:0061706	biolink:NamedThing	glycolytic process from sucrose through glucose and fructose	The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.	got7fsn_ti							dph	2015-06-11T13:40:32Z				MetaCyc:PWY-1042		biological_process											owl:Class	
GO:0061704	biolink:NamedThing	glycolytic process from sucrose	The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.	got7fsn_ti							dph	2015-06-11T13:26:28Z						biological_process											owl:Class	
GO:0005178	biolink:NamedThing	integrin binding	Binding to an integrin.	got7fsn_ti	integrin ligand													molecular_function											owl:Class	
GO:0009867	biolink:NamedThing	jasmonic acid mediated signaling pathway	A series of molecular signals mediated by jasmonic acid.	got7fsn_ti	JA signaling|jasmonate signaling|jasmonic acid mediated signalling pathway													biological_process											owl:Class	
GO:0097023	biolink:NamedThing	fructose 6-phosphate aldolase activity	Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate.	got7fsn_ti							pr	2011-03-29T04:54:05Z				RHEA:28002		molecular_function											owl:Class	
GO:0039699	biolink:NamedThing	viral mRNA cap methylation	Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a viral mRNA. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs.	got7fsn_ti	IFIT mRNA restriction evasion by virus						bf	2013-11-06T14:39:17Z						biological_process											owl:Class	
GO:0046793	biolink:NamedThing	induction by virus of phosphorylation of host RNA polymerase II	Any process in which a virus activates the frequency, rate or extent of phosphorylation of host RNA polymerase II.	got7fsn_ti	virus-induced modification of host RNA polymerase II|induction by virus of modification of host RNA polymerase II													biological_process											owl:Class	
GO:0019056	biolink:NamedThing	modulation by virus of host transcription	Any process in which a virus modulates the frequency, rate or extent of its host's transcription.	got7fsn_ti	modification by virus of host transcription|viral perturbation of host cell transcription													biological_process											owl:Class	
GO:0061800	biolink:NamedThing	fibronectin fibril	A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks.	got7fsn_ti							dph	2016-10-24T14:04:21Z						cellular_component											owl:Class	
GO:0039604	biolink:NamedThing	suppression by virus of host translation	Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA.	got7fsn_ti	host translation shutoff by virus|viral inhibition of cellular protein synthesis|viral shutoff of host protein synthesis						bf	2012-07-05T04:25:22Z				VZ:1579		biological_process											owl:Class	
GO:0039657	biolink:NamedThing	suppression by virus of host gene expression	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.	got7fsn_ti	host gene expression shutoff by virus						bf	2013-06-20T15:29:55Z				VZ:1582		biological_process											owl:Class	
GO:0047306	biolink:NamedThing	D-methionine-pyruvate transaminase activity	Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine.	got7fsn_ti	D-methionine:pyruvate aminotransferase activity|D-methionine aminotransferase activity|D-methionine--pyruvate aminotransferase activity|D-methionine-pyruvate aminotransferase activity|D-methionine transaminase activity											RHEA:23836|KEGG_REACTION:R03001|MetaCyc:2.6.1.41-RXN|EC:2.6.1.41		molecular_function											owl:Class	
GO:0019782	biolink:NamedThing	ISG15 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti	UBE1L													molecular_function											owl:Class	
GO:0097594	biolink:NamedThing	ventral disc dorsal microribbon	Trilaminar structure extending perpendicularly into the cytoplasm along the length of ventral disc microtubules in Giardia species (trophozoite stage). Constituents of dorsal microribbons (also called dorsal ribbons or microribbons) include alpha-coiled-helix proteins approximately 29 to 38 kDa in size. These proteins line the edges of the microribbons but are not found in microtubules. Tubulins are not found in microribbons.	got7fsn_ti	ventral disk dorsal microribbon|dorsal ribbon|microribbon|dorsal microribbon				Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:20:06Z						cellular_component											owl:Class	
GO:0004132	biolink:NamedThing	dCMP deaminase activity	Catalysis of the reaction: dCMP + H2O = dUMP + NH3.	got7fsn_ti	deoxycytidine-5'-monophosphate aminohydrolase activity|deoxycytidine-5'-phosphate deaminase activity|deoxycytidine monophosphate deaminase activity|dCMP aminohydrolase activity|deoxycytidylate deaminase activity|deoxycytidylate aminohydrolase activity|deoxy-CMP-deaminase activity											RHEA:22924|EC:3.5.4.12|MetaCyc:DCMP-DEAMINASE-RXN|Reactome:R-HSA-73596		molecular_function											owl:Class	
GO:0019083	biolink:NamedThing	viral transcription	The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.	got7fsn_ti														biological_process											owl:Class	
GO:1990136	biolink:NamedThing	linoleate 9S-lipoxygenase activity	Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.	got7fsn_ti	linoleate 9-lipoxygenase activity|9-lipoxygenase activity|linoleate:oxygen 9S-oxidoreductase activity|9S-lipoxygenase activity						pr	2013-07-03T12:20:57Z				EC:1.13.11.58|RHEA:30291		molecular_function											owl:Class	
GO:0010467	biolink:NamedThing	gene expression	The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	got7fsn_ti												Wikipedia:Gene_expression		biological_process											owl:Class	
GO:0036471	biolink:NamedThing	cellular response to glyoxal	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus.	got7fsn_ti							bf	2014-07-21T11:14:33Z						biological_process											owl:Class	
GO:0047828	biolink:NamedThing	D-lyxose ketol-isomerase activity	Catalysis of the reaction: D-lyxose = D-xylulose.	got7fsn_ti	D-lyxose isomerase activity|D-lyxose aldose-ketose-isomerase activity											RHEA:14201|EC:5.3.1.15|KEGG_REACTION:R01898|MetaCyc:D-LYXOSE-KETOL-ISOMERASE-RXN		molecular_function											owl:Class	
GO:0050976	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of touch	The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.	got7fsn_ti	perception of touch, sensory transduction of mechanical stimulus|tactition, sensory detection of mechanical stimulus|perception of touch, sensory detection of mechanical stimulus|sensory detection of mechanical stimulus during perception of touch|perception of touch, detection of mechanical stimulus|sensory transduction of mechanical stimulus during perception of touch													biological_process											owl:Class	
GO:0050974	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception	The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.	got7fsn_ti	sensory perception, sensory transduction of mechanical stimulus|sensory perception, sensory detection of mechanical stimulus|sensory transduction of mechanical stimulus during sensory perception|sensory detection of mechanical stimulus during sensory perception|sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus													biological_process											owl:Class	
GO:0061025	biolink:NamedThing	membrane fusion	The membrane organization process that joins two lipid bilayers to form a single membrane.	got7fsn_ti	cellular membrane fusion|single-organism membrane fusion						jl	2010-02-08T02:48:06Z			GO:0006944|GO:0044801	Wikipedia:Lipid_bilayer_fusion		biological_process											owl:Class	
GO:0033912	biolink:NamedThing	2,6-beta-fructan 6-levanbiohydrolase activity	Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.	got7fsn_ti	2,6-beta-D-fructan 6-levanbiohydrolase activity|2,6-beta-D-fructofuranan 6-(beta-D-fructosyl)-D-fructose-hydrolase activity|2,6-beta-D-fructan 6-beta-D-fructofuranosylfructohydrolase activity|beta-2,6-fructan-6-levanbiohydrolase activity|levanbiose-producing levanase activity											EC:3.2.1.64|MetaCyc:3.2.1.64-RXN		molecular_function											owl:Class	
GO:0102136	biolink:NamedThing	3-epi-6-deoxocathasterone C-23 hydroxylase activity	Catalysis of the reaction: H+ + 3-epi-6-deoxocathasterone + reduced (NADPH-hemoprotein reducdtase) + O2 = 6=deoxotyphasterol + oxidized (NADPH-hemoprotein reductase) + H2O.	got7fsn_ti												EC:1.14.14.147|MetaCyc:RXN-11531|RHEA:27321		molecular_function											owl:Class	
GO:0050457	biolink:NamedThing	decylcitrate synthase activity	Catalysis of the reaction: H(2)O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+).	got7fsn_ti	(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-acylating)|2-decylcitrate synthase activity|(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA- acylating) activity|dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)											MetaCyc:DECYLCITRATE-SYNTHASE-RXN|RHEA:16605|KEGG_REACTION:R03735|EC:2.3.3.2		molecular_function											owl:Class	
GO:0050793	biolink:NamedThing	regulation of developmental process	Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	got7fsn_ti														biological_process											owl:Class	
GO:0035095	biolink:NamedThing	behavioral response to nicotine	Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.	got7fsn_ti	behavioural response to nicotine													biological_process											owl:Class	
GO:0030534	biolink:NamedThing	adult behavior	Behavior in a fully developed and mature organism.	got7fsn_ti	adult behavioural response to stimulus|adult behavioral response to stimulus|adult behaviour				See also the biological process term 'behavior ; GO:0007610'.									biological_process											owl:Class	
GO:0072682	biolink:NamedThing	eosinophil extravasation	The migration of an eosinophil from the blood vessels into the surrounding tissue.	got7fsn_ti							mah	2011-02-22T04:02:22Z						biological_process											owl:Class	
GO:0072677	biolink:NamedThing	eosinophil migration	The movement of an eosinophil within or between different tissues and organs of the body.	got7fsn_ti							mah	2011-02-22T03:39:31Z						biological_process											owl:Class	
GO:0035936	biolink:NamedThing	testosterone secretion	The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.	got7fsn_ti							bf	2011-07-20T01:13:13Z						biological_process											owl:Class	
GO:0046879	biolink:NamedThing	hormone secretion	The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells.	got7fsn_ti														biological_process											owl:Class	
GO:1990326	biolink:NamedThing	collagen type XXVIII trimer	A collagen homotrimer of alpha1(XXVIII) chains.	got7fsn_ti							bhm	2014-03-16T23:15:28Z						cellular_component											owl:Class	
GO:0033678	biolink:NamedThing	5'-3' DNA/RNA helicase activity	Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent 5'-3' DNA/RNA helicase activity|ATP-dependent 5' to 3' DNA/RNA helicase activity|5' to 3' DNA/RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612									GO:0033682	Reactome:R-HSA-163120		molecular_function											owl:Class	
GO:0033677	biolink:NamedThing	DNA/RNA helicase activity	Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent DNA/RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612									GO:0033680			molecular_function											owl:Class	
GO:0018801	biolink:NamedThing	glutaconyl-CoA decarboxylase activity	Catalysis of the reaction: trans-glutaconyl-CoA + H(+) = but-2-enoyl-CoA + CO(2).	got7fsn_ti	4-carboxybut-2-enoyl-CoA carboxy-lyase activity|glutaconyl coenzyme A decarboxylase activity|4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming)|pent-2-enoyl-CoA carboxy-lyase activity											EC:7.2.4.5|KEGG_REACTION:R03028|RHEA:23972|MetaCyc:GLUTACONYL-COA-DECARBOXYLASE-RXN|UM-BBD_reactionID:r0199		molecular_function											owl:Class	
GO:0002568	biolink:NamedThing	somatic diversification of T cell receptor genes	The somatic process that results in the generation of sequence diversity of T cell receptor genes.	got7fsn_ti	somatic diversification of TCR genes													biological_process											owl:Class	
GO:0033984	biolink:NamedThing	indole-3-glycerol-phosphate lyase activity	Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate.	got7fsn_ti	indole synthase activity|indole-3-glycerol phosphate lyase activity|BX1|tryptophan synthase alpha subunit activity|indole glycerol phosphate hydrolase activity|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase (indole-forming) activity|TSA|tryptophan synthase alpha activity|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase activity|indoleglycerolphosphate aldolase activity|indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase activity|IGL											KEGG_REACTION:R02340|MetaCyc:4.1.2.8-RXN|MetaCyc:RXN0-2381|EC:4.1.2.8|RHEA:14081		molecular_function											owl:Class	
GO:0000142	biolink:NamedThing	cellular bud neck contractile ring	A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae.	got7fsn_ti	neck ring													cellular_component											owl:Class	
GO:0110085	biolink:NamedThing	mitotic actomyosin contractile ring	A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis.	got7fsn_ti							kmv	2018-02-12T17:04:02Z						cellular_component											owl:Class	
GO:0005802	biolink:NamedThing	trans-Golgi network	The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.	got7fsn_ti	late Golgi|maturing face|TGN|trans Golgi network|trans face|Golgi trans face|Golgi trans-face				There are different opinions about whether the TGN should be considered part of the Golgi apparatus or not.  We follow Alberts et al, 1994 (ISBN:0815316194), who consider it to be a part.							NIF_Subcellular:sao9456487		cellular_component											owl:Class	
GO:1990432	biolink:NamedThing	siRNA 3'-end processing	The process of forming the mature 3' end of a siRNA molecule.	got7fsn_ti	siRNA 3' end processing|small interfering RNA 3'-end processing						jl	2014-07-29T15:38:38Z						biological_process											owl:Class	
GO:0102541	biolink:NamedThing	D-galactose 6-phosphate 1-epimerase activity	Catalysis of the reaction: alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate.	got7fsn_ti												MetaCyc:RXN-14816		molecular_function											owl:Class	
GO:0008421	biolink:NamedThing	long-chain fatty-acyl-glutamate deacylase activity	Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate.	got7fsn_ti	N-long-chain-fatty-acyl-L-glutamate amidohydrolase activity|long-chain acylglutamate amidase activity|long-chain-fatty-acyl-glutamate deacylase activity|long-chain fatty acyl-glutamate deacylase activity|long-chain aminoacylase activity											MetaCyc:3.5.1.55-RXN|EC:3.5.1.55|RHEA:17517		molecular_function											owl:Class	
GO:0097114	biolink:NamedThing	NMDA glutamate receptor clustering	The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.	got7fsn_ti	NMDA receptor clustering|N-methyl-D-aspartate receptor clustering						pr	2011-07-31T05:30:15Z						biological_process											owl:Class	
GO:0033765	biolink:NamedThing	steroid dehydrogenase activity, acting on the CH-CH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0016229	biolink:NamedThing	steroid dehydrogenase activity	Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0048925	biolink:NamedThing	lateral line system development	The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.	got7fsn_ti														biological_process											owl:Class	
GO:0048880	biolink:NamedThing	sensory system development	The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0098022	biolink:NamedThing	viral capsid, fiber	A type of capsid decoration composed of fiber structures.	got7fsn_ti	head/capsid fiber						bm	2012-07-19T11:56:32Z						cellular_component											owl:Class	
GO:0098021	biolink:NamedThing	viral capsid, decoration	Component of the virus capsid (head), located on the outer head surface. Involved in the stabilization of the head structure and usually non-essential.	got7fsn_ti	decoration protein						bm	2012-07-19T11:52:53Z						cellular_component											owl:Class	
GO:0051721	biolink:NamedThing	protein phosphatase 2A binding	Binding to protein phosphatase 2A.	got7fsn_ti	protein phosphatase 2 binding													molecular_function											owl:Class	
GO:0019903	biolink:NamedThing	protein phosphatase binding	Binding to a protein phosphatase.	got7fsn_ti														molecular_function											owl:Class	
GO:0004045	biolink:NamedThing	aminoacyl-tRNA hydrolase activity	Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.	got7fsn_ti	N-substituted aminoacyl transfer RNA hydrolase activity|aminoacyl-tRNA hydrolase reaction|peptidyl-tRNA hydrolase activity|aminoacyl-transfer ribonucleate hydrolase activity|D-tyrosyl-tRNA hydrolase activity|aminoacyl-tRNA aminoacylhydrolase activity										GO:0019851|GO:0019850	MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN|EC:3.1.1.29|RHEA:54448		molecular_function											owl:Class	
GO:0030298	biolink:NamedThing	receptor signaling protein tyrosine kinase activator activity	Binds to and increases the activity of a receptor signaling protein tyrosine kinase.	got7fsn_ti	receptor signalling protein tyrosine kinase activator activity													molecular_function											owl:Class	
GO:0030296	biolink:NamedThing	protein tyrosine kinase activator activity	Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0032151	biolink:NamedThing	mitotic septin complex	A heterooligomeric septin complex that acts during mitotic cell division.	got7fsn_ti														cellular_component											owl:Class	
GO:0031105	biolink:NamedThing	septin complex	A protein complex containing septins.  Typically, these complexes contain multiple septins and are oligomeric.	got7fsn_ti														cellular_component											owl:Class	
GO:0038190	biolink:NamedThing	VEGF-activated neuropilin signaling pathway	A series of molecular signals initiated by the binding of vascular endothelial growth factor (VEGF) to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	vascular endothelial growth factor-activated neuropilin signaling pathway|VEGF-Npn-1 signaling						bf	2013-08-01T16:06:49Z						biological_process											owl:Class	
GO:0038084	biolink:NamedThing	vascular endothelial growth factor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	VEGF-activated signaling pathway|vascular endothelial growth factor signalling pathway|VEGF signaling				In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'.		bf	2012-02-01T02:27:32Z						biological_process											owl:Class	
GO:0060233	biolink:NamedThing	oenocyte delamination	The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet.	got7fsn_ti														biological_process											owl:Class	
GO:0060232	biolink:NamedThing	delamination	The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet.	got7fsn_ti														biological_process											owl:Class	
GO:0061034	biolink:NamedThing	olfactory bulb mitral cell layer development	The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.	got7fsn_ti							dph	2010-02-09T03:30:23Z						biological_process											owl:Class	
GO:0018858	biolink:NamedThing	benzoate-CoA ligase activity	Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate.	got7fsn_ti	benzoate-coenzyme A ligase activity|benzoate:CoA ligase (AMP-forming)|benzoyl CoA synthetase (AMP forming)|benzoyl-coenzyme A synthetase activity											KEGG_REACTION:R01422|MetaCyc:BENZOATE--COA-LIGASE-RXN|RHEA:10132|EC:6.2.1.25|UM-BBD_reactionID:r0189		molecular_function											owl:Class	
GO:0034630	biolink:NamedThing	RITS complex localization	Any process in which a RITS complex is transported to, or maintained in, a specific location.	got7fsn_ti	RITS complex localisation|establishment and maintenance of RITS complex localization													biological_process											owl:Class	
GO:0043715	biolink:NamedThing	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity	Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.	got7fsn_ti	mtnW|DK-MTP-1-P enolase activity|MasA|E-1				This function is part of the process of methionine salvage.							EC:5.3.2.5|MetaCyc:R82-RXN|RHEA:18769		molecular_function											owl:Class	
GO:0002458	biolink:NamedThing	peripheral T cell tolerance induction	Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus.	got7fsn_ti	peripheral T-lymphocyte tolerance induction|peripheral T-cell tolerance induction|peripheral T lymphocyte tolerance induction													biological_process											owl:Class	
GO:0002517	biolink:NamedThing	T cell tolerance induction	A process involving any mechanism for tolerance induction in T cells.	got7fsn_ti	T-lymphocyte tolerance induction|T-cell tolerance induction|T lymphocyte tolerance induction													biological_process											owl:Class	
GO:0033093	biolink:NamedThing	Weibel-Palade body	A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses.	got7fsn_ti												Wikipedia:Weibel-Palade_body		cellular_component											owl:Class	
GO:0030136	biolink:NamedThing	clathrin-coated vesicle	A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.	got7fsn_ti												NIF_Subcellular:sao148845161		cellular_component											owl:Class	
GO:0102674	biolink:NamedThing	C4-demethylase activity	Catalysis of the reaction: 24-methylenelophenol + a demethylated methyl acceptor <=> 9xi-episterol + a methylated methyl acceptor.	got7fsn_ti												MetaCyc:RXN-4181		molecular_function											owl:Class	
GO:0022839	biolink:NamedThing	ion gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.	got7fsn_ti														molecular_function											owl:Class	
GO:0061205	biolink:NamedThing	paramesonephric duct development	The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.	got7fsn_ti	Mullerian duct development						dph	2010-07-30T10:54:47Z						biological_process											owl:Class	
GO:0016501	biolink:NamedThing	prostacyclin receptor activity	Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.	got7fsn_ti	PGI receptor activity|PGI(2) receptor activity|prostaglandin I receptor activity										GO:0004959			molecular_function											owl:Class	
GO:0001826	biolink:NamedThing	inner cell mass cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.	got7fsn_ti					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'.									biological_process											owl:Class	
GO:0033567	biolink:NamedThing	DNA replication, Okazaki fragment processing	The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.	got7fsn_ti														biological_process											owl:Class	
GO:0071572	biolink:NamedThing	histone H3-K56 deacetylation	The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone.	got7fsn_ti							mah	2010-01-20T04:50:03Z						biological_process											owl:Class	
GO:0070932	biolink:NamedThing	histone H3 deacetylation	The modification of histone H3 by the removal of one or more acetyl groups.	got7fsn_ti							mah	2009-09-16T04:50:55Z						biological_process											owl:Class	
GO:0018355	biolink:NamedThing	protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine	The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine.	got7fsn_ti														biological_process											owl:Class	
GO:0018247	biolink:NamedThing	protein-phosphoribosyl dephospho-coenzyme A linkage	The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position.	got7fsn_ti												RESID:AA0167		biological_process											owl:Class	
GO:0017125	biolink:NamedThing	deoxycytidyl transferase activity	Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA.	got7fsn_ti	deoxycytidyl transferase activity, template-dependent										GO:0019986	Reactome:R-HSA-110308		molecular_function											owl:Class	
GO:0035991	biolink:NamedThing	nitric oxide sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO).	got7fsn_ti	NO sensor activity						bf	2011-08-26T04:32:16Z						molecular_function											owl:Class	
GO:0070026	biolink:NamedThing	nitric oxide binding	Binding to nitric oxide (NO).	got7fsn_ti	NO binding|nitrosyl binding|nitrogen monoxide binding													molecular_function											owl:Class	
GO:0019577	biolink:NamedThing	aldaric acid metabolic process	The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.	got7fsn_ti	aldaric acid metabolism													biological_process											owl:Class	
GO:0005975	biolink:NamedThing	carbohydrate metabolic process	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.	got7fsn_ti	multicellular organismal carbohydrate metabolic process|single-organism carbohydrate metabolic process|carbohydrate metabolism						jl	2012-10-23T15:40:34Z			GO:0044723|GO:0044261	Wikipedia:Carbohydrate_metabolism		biological_process											owl:Class	
GO:1990762	biolink:NamedThing	cytoplasmic alanyl-tRNA aminoacylation	The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation.	got7fsn_ti							vw	2015-06-08T15:56:51Z						biological_process											owl:Class	
GO:0006419	biolink:NamedThing	alanyl-tRNA aminoacylation	The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a  class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0072256	biolink:NamedThing	metanephric glomerular mesangial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.	got7fsn_ti							mah	2010-03-19T04:07:10Z						biological_process											owl:Class	
GO:0072152	biolink:NamedThing	glomerular mesangial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell.	got7fsn_ti							mah	2010-02-24T02:14:58Z						biological_process											owl:Class	
GO:0010333	biolink:NamedThing	terpene synthase activity	Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.	got7fsn_ti														molecular_function											owl:Class	
GO:0042960	biolink:NamedThing	antimonite secondary active transmembrane transporter activity	Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	antimonite porter activity													molecular_function											owl:Class	
GO:0061630	biolink:NamedThing	ubiquitin protein ligase activity	Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.	got7fsn_ti	ubiquitin ligase activity involved in ER-associated degradation pathway|E3 involved in endoplasmic reticulum-associated degradation|ubiquitin protein ligase activity involved in ER-associated degradation pathway|ubiquitin-protein ligase activity involved in positive regulation of mitotic metaphase/anaphase transition|ubiquitin protein ligase activity involved in ERAD pathway|ubiquitin protein ligase activity involved in chloroplast disassembly|ER-associated E3 ligase|APC-Cdc20 complex activity|APC-fizzy related complex activity|ubiquitin ligase activity|protein ubiquitination activity|E3				This enzyme catalyzes a transferase reaction.		dph	2014-05-18T09:11:21Z			GO:0090302|GO:1904822|GO:0090622|GO:1904264	Reactome:R-HSA-8854051|Reactome:R-HSA-9009308|Reactome:R-HSA-4608852|Reactome:R-HSA-8942101|Reactome:R-HSA-5674022|Reactome:R-HSA-5690827|Reactome:R-HSA-5632648|Reactome:R-HSA-1504190|Reactome:R-HSA-5682858|Reactome:R-HSA-8943040|Reactome:R-HSA-6804879|Reactome:R-HSA-8956684|Reactome:R-HSA-8943003|Reactome:R-HSA-8953946|Reactome:R-HSA-201445|Reactome:R-HSA-3640861|Reactome:R-HSA-9686969|Reactome:R-HSA-5610737|Reactome:R-HSA-6804724|Reactome:R-HSA-8948775|Reactome:R-HSA-68946|Reactome:R-HSA-8943080|Reactome:R-HSA-4641159|Reactome:R-HSA-5654677|Reactome:R-HSA-6804441|Reactome:R-HSA-8851011|Reactome:R-HSA-9604629|Reactome:R-HSA-6804253|Reactome:R-HSA-6782943|Reactome:R-HSA-9008479|Reactome:R-HSA-5654684|Reactome:R-HSA-8939706|Reactome:R-HSA-6807134|Reactome:R-HSA-3322429|Reactome:R-HSA-8875431|Reactome:R-HSA-8875183|Reactome:R-HSA-6798373|Reactome:R-HSA-9011300|Reactome:R-HSA-8848829|Reactome:R-HSA-6781867|Reactome:R-HSA-9021523|Reactome:R-HSA-8938773|Reactome:R-HSA-8952382|Reactome:R-HSA-8956026|Reactome:R-HSA-9706354|Reactome:R-HSA-936462|Reactome:R-HSA-9686920|Reactome:R-HSA-8866546|Reactome:R-HSA-8867288|Reactome:R-HSA-4641129|Reactome:R-HSA-6785361|Reactome:R-HSA-8877003|Reactome:R-HSA-8938815|Reactome:R-HSA-6807106|Reactome:R-HSA-5687081|Reactome:R-HSA-4641253|Reactome:R-HSA-990526|Reactome:R-HSA-5635856|Reactome:R-HSA-9008076|Reactome:R-HSA-5654679|Reactome:R-HSA-5635864|Reactome:R-HSA-8866856|Reactome:R-HSA-6790487|Reactome:R-HSA-5246693|Reactome:R-HSA-69015|Reactome:R-HSA-8948832|Reactome:R-HSA-5689111|Reactome:R-HSA-5658424|Reactome:R-HSA-4641246|Reactome:R-HSA-8939335|Reactome:R-HSA-5684071|Reactome:R-HSA-5654672|Reactome:R-HSA-934604|Reactome:R-HSA-8952419|Reactome:R-HSA-8876258|Reactome:R-HSA-936475|Reactome:R-HSA-8854628|Reactome:R-HSA-8854041|Reactome:R-HSA-6804942|Reactome:R-HSA-9706356|Reactome:R-HSA-1225956|Reactome:R-HSA-9009403|Reactome:R-HSA-9033485		molecular_function											owl:Class	
GO:0004842	biolink:NamedThing	ubiquitin-protein transferase activity	Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.	got7fsn_ti	E2|ubiquitin conjugating enzyme activity|ubiquitin protein ligase activity|E3|ubiquitin protein-ligase activity|ubiquitin ligase activity|ubiquitin-conjugating enzyme activity|anaphase-promoting complex activity										GO:0004840|GO:0004841	Reactome:R-HSA-1253282|Reactome:R-HSA-5660753|Reactome:R-HSA-1234172|Reactome:R-HSA-2730904|Reactome:R-HSA-5610745|Reactome:R-HSA-3797226|Reactome:R-HSA-1852623|Reactome:R-HSA-9013069|Reactome:R-HSA-1912386|Reactome:R-HSA-5610746|Reactome:R-HSA-180540|Reactome:R-HSA-211734|Reactome:R-HSA-1234163|Reactome:R-HSA-9688831|Reactome:R-HSA-3781009|Reactome:R-HSA-2172172|Reactome:R-HSA-1358789|Reactome:R-HSA-8956106|Reactome:R-HSA-5693108|Reactome:R-HSA-182993|Reactome:R-HSA-183051|Reactome:R-HSA-2187368|Reactome:R-HSA-187575|Reactome:R-HSA-5362412|Reactome:R-HSA-168915|Reactome:R-HSA-2900765|Reactome:R-HSA-3134946|Reactome:R-HSA-741386|Reactome:R-HSA-174057|Reactome:R-HSA-983140|KEGG_REACTION:R03876|Reactome:R-HSA-2737728|Reactome:R-HSA-5655170|Reactome:R-HSA-1169402|Reactome:R-HSA-205118|Reactome:R-HSA-183036|Reactome:R-HSA-936942|Reactome:R-HSA-2169050|Reactome:R-HSA-201425|Reactome:R-HSA-3000335|Reactome:R-HSA-3249386|Reactome:R-HSA-5607756|Reactome:R-HSA-9645414|Reactome:R-HSA-180597|Reactome:R-HSA-936412|Reactome:R-HSA-1358792|Reactome:R-HSA-174227|Reactome:R-HSA-450358|Reactome:R-HSA-5607728|Reactome:R-HSA-5667111|Reactome:R-HSA-1169394|Reactome:R-HSA-5357757|Reactome:R-HSA-5652009|Reactome:R-HSA-183084|Reactome:R-HSA-69598|Reactome:R-HSA-1169398|Reactome:R-HSA-1977296|Reactome:R-HSA-983156|Reactome:R-HSA-75824|Reactome:R-HSA-5610742|Reactome:R-HSA-3780995|Reactome:R-HSA-173545|Reactome:R-HSA-2179276|Reactome:R-HSA-1169397|Reactome:R-HSA-3134804|Reactome:R-HSA-174195|Reactome:R-HSA-1980118|Reactome:R-HSA-9645394|Reactome:R-HSA-446877|Reactome:R-HSA-4332236|Reactome:R-HSA-1918092|Reactome:R-HSA-5483238|Reactome:R-HSA-9628444|Reactome:R-HSA-1363331|Reactome:R-HSA-9013974|Reactome:R-HSA-2682349|Reactome:R-HSA-183089|Reactome:R-HSA-870449|Reactome:R-HSA-202453|Reactome:R-HSA-2213017|Reactome:R-HSA-1169405|Reactome:R-HSA-9701000|Reactome:R-HSA-5691108|Reactome:R-HSA-209063|Reactome:R-HSA-5668534|Reactome:R-HSA-179417|Reactome:R-HSA-5667107|Reactome:R-HSA-918224|Reactome:R-HSA-5675470|Reactome:R-HSA-2769007|Reactome:R-HSA-5205682|Reactome:R-HSA-5607725|Reactome:R-HSA-5607757|Reactome:R-HSA-975118|Reactome:R-HSA-400267|Reactome:R-HSA-1169406|Reactome:R-HSA-1169395|Reactome:R-HSA-1980074|Reactome:R-HSA-182986|Reactome:R-HSA-174144|Reactome:R-HSA-264444|Reactome:R-HSA-3788724|Reactome:R-HSA-5668454|Reactome:R-HSA-2186747|Reactome:R-HSA-5684250|Reactome:R-HSA-975147|Reactome:R-HSA-451418|Reactome:R-HSA-1912357|Reactome:R-HSA-174104|Reactome:R-HSA-1918095|Reactome:R-HSA-8948709|Reactome:R-HSA-173542|Reactome:R-HSA-983153|Reactome:R-HSA-202534|Reactome:R-HSA-9014342|Reactome:R-HSA-174159|Reactome:R-HSA-1358790|Reactome:R-HSA-2186785|Reactome:R-HSA-936986		molecular_function											owl:Class	
GO:0017067	biolink:NamedThing	tyrosine-ester sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H(+).	got7fsn_ti	aryl sulfotransferase IV|tyrosine-ester sulphotransferase activity|L-tyrosine methyl ester sulfotransferase activity|3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase activity										GO:0008128	KEGG_REACTION:R04213|MetaCyc:TYROSINE-ESTER-SULFOTRANSFERASE-RXN|EC:2.8.2.9|RHEA:19977		molecular_function											owl:Class	
GO:0048796	biolink:NamedThing	swim bladder maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	got7fsn_ti	gas bladder maturation													biological_process											owl:Class	
GO:0102327	biolink:NamedThing	3-oxoacyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a 3-oxoacyl-CoA = H+ + coenzyme A + a 3-oxoacid.	got7fsn_ti												MetaCyc:RXN-13247		molecular_function											owl:Class	
GO:0016790	biolink:NamedThing	thiolester hydrolase activity	Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.	got7fsn_ti	thiolesterase activity											EC:3.1.2.-		molecular_function											owl:Class	
GO:2000871	biolink:NamedThing	negative regulation of progesterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion.	got7fsn_ti							bf	2011-07-26T08:51:19Z						biological_process											owl:Class	
GO:2000832	biolink:NamedThing	negative regulation of steroid hormone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion.	got7fsn_ti							bf	2011-07-26T08:38:50Z						biological_process											owl:Class	
GO:0071625	biolink:NamedThing	vocalization behavior	The behavior in which an organism produces sounds by a mechanism involving its respiratory system.	got7fsn_ti	vocalisation behaviour						mah	2010-02-10T11:02:58Z						biological_process											owl:Class	
GO:0007610	biolink:NamedThing	behavior	The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.	got7fsn_ti	behavioral response to stimulus|behaviour|single-organism behavior|behavioural response to stimulus				1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. 2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).		jl	2012-09-20T14:06:08Z			GO:0023032|GO:0044709|GO:0044708	Wikipedia:Behavior		biological_process											owl:Class	
GO:0005158	biolink:NamedThing	insulin receptor binding	Binding to an insulin receptor.	got7fsn_ti	insulin receptor ligand													molecular_function											owl:Class	
GO:0002509	biolink:NamedThing	central tolerance induction to self antigen	Tolerance induction in the central lymphoid organs directed at self antigens.	got7fsn_ti														biological_process											owl:Class	
GO:0048581	biolink:NamedThing	negative regulation of post-embryonic development	Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.	got7fsn_ti	inhibition of post-embryonic development|down regulation of post-embryonic development|downregulation of post-embryonic development|down-regulation of post-embryonic development													biological_process											owl:Class	
GO:0140567	biolink:NamedThing	transmembrane protein dislocase activity	The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers.	got7fsn_ti	transmembrane helix dislocase	https://github.com/geneontology/go-ontology/issues/20237					pg	2020-12-15T07:13:21Z				RHEA:66168		molecular_function											owl:Class	
GO:0140318	biolink:NamedThing	protein transporter activity	Directly binding to a specific protein and delivering it to a specific cellular location.	got7fsn_ti	protein transport chaperone|protein carrier activity	https://github.com/geneontology/go-ontology/issues/17073			Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation.		pg	2019-04-01T10:41:38Z				Reactome:R-HSA-9662747|Reactome:R-HSA-9662818		molecular_function											owl:Class	
GO:0004338	biolink:NamedThing	glucan exo-1,3-beta-glucosidase activity	Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.	got7fsn_ti	exo-1,3-beta-D-glucanase activity|1,3-beta-glucan glucohydrolase activity|exo-beta-(1->3)-glucanohydrolase activity|exo (1->3)-beta-glucanase activity|exo-1,3-beta-glucanase activity|exo-1,3-beta-glucosidase activity|exo-beta-1,3-glucanase activity|exo-beta-1,3-D-glucanase activity|beta-1,3-glucan exo-hydrolase activity|glucan 1,3-beta-glucosidase activity|exo-beta-(1->3)-D-glucanase activity											EC:3.2.1.58|MetaCyc:3.2.1.58-RXN		molecular_function											owl:Class	
GO:0034150	biolink:NamedThing	toll-like receptor 6 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 6.	got7fsn_ti	toll-like receptor 6 signalling pathway|TLR6 signaling pathway													biological_process											owl:Class	
GO:0002224	biolink:NamedThing	toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	got7fsn_ti	toll-like receptor signalling pathway|TLR signaling pathway				Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses.									biological_process											owl:Class	
GO:0045201	biolink:NamedThing	maintenance of neuroblast polarity	The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.	got7fsn_ti	maintenance of neuroblast cell polarity										GO:0043341|GO:0043344			biological_process											owl:Class	
GO:0075192	biolink:NamedThing	haustorium mother cell formation	The process in which a symbiont cell is formed, separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	haustorium mother cell formation on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0075015	biolink:NamedThing	formation of infection structure	The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	formation by symbiont of infection structure on or near host|formation of host infection structure|formation of host penetration structure|formation of infection structure on or near host	https://github.com/geneontology/go-ontology/issues/20472|https://github.com/geneontology/go-ontology/issues/19014			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products of the symbiont involved in this process.									biological_process											owl:Class	
GO:0102606	biolink:NamedThing	octat-9-en-7-ol 5-monooxygenase activity	Catalysis of the reaction: cyclooctat-9-en-7-ol + O2 + NADPH + H+ <=> cyclooctat-9-en-5,7-diol + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-15431|RHEA:56820		molecular_function											owl:Class	
GO:0004782	biolink:NamedThing	sulfinoalanine decarboxylase activity	Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2.	got7fsn_ti	L-cysteinesulfinic acid decarboxylase activity|sulphinoalanine decarboxylase activity|CSADCase activity|cysteine-sulfinate decarboxylase activity|sulfoalanine decarboxylase activity|CADCase/CSADCase activity|cysteinesulfinic acid decarboxylase activity|cysteic decarboxylase activity|3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)|cysteinesulfinate decarboxylase activity|CSAD|3-sulfino-L-alanine carboxy-lyase activity											RHEA:16877|Reactome:R-HSA-1655443|EC:4.1.1.29|MetaCyc:SULFINOALANINE-DECARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0035194	biolink:NamedThing	post-transcriptional gene silencing by RNA	Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation.	got7fsn_ti	sense-PTGS|RNA-mediated posttranscriptional gene silencing|posttranscriptional gene silencing by RNA													biological_process											owl:Class	
GO:0016441	biolink:NamedThing	posttranscriptional gene silencing	The inactivation of gene expression by a posttranscriptional mechanism.	got7fsn_ti	quelling|PTGS|post-transcriptional gene silencing|cosuppression											Wikipedia:Post_transcriptional_gene_silencing		biological_process											owl:Class	
GO:0045486	biolink:NamedThing	naringenin 3-dioxygenase activity	Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2.	got7fsn_ti	flavanone 3-dioxygenase activity|flavanone 3-beta-hydroxylase activity|(2S)-flavanone 3-hydroxylase activity|flavanone synthase I activity|flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|naringenin 3-hydroxylase activity|flavanone 3-hydroxylase activity|naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|flavanone 3beta-hydroxylase activity											MetaCyc:NARINGENIN-3-DIOXYGENASE-RXN|RHEA:18621|EC:1.14.11.9		molecular_function											owl:Class	
GO:0032624	biolink:NamedThing	interleukin-20 production	The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-20 production|interleukin-20 biosynthetic process|interleukin-20 secretion|ZCYTO10 production										GO:0042237|GO:0072618			biological_process											owl:Class	
GO:0052800	biolink:NamedThing	bicyclic nitroimidazole catabolic process	The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole.	got7fsn_ti	bicyclic nitroimidazole catabolism|bicyclic nitroimidazole breakdown|bicyclic nitroimidazole degradation													biological_process											owl:Class	
GO:0052804	biolink:NamedThing	nitroimidazole catabolic process	The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.	got7fsn_ti	nitroimidazole degradation|nitroimidazole breakdown|nitroimidazole catabolism													biological_process											owl:Class	
GO:0021579	biolink:NamedThing	medulla oblongata morphogenesis	The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	got7fsn_ti	medulla morphogenesis|myelencephalon morphogenesis													biological_process											owl:Class	
GO:0043640	biolink:NamedThing	benzoate catabolic process via hydroxylation	The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol.	got7fsn_ti	benzoate breakdown via hydroxylation|benzoate degradation via hydroxylation											MetaCyc:PWY-2503		biological_process											owl:Class	
GO:0043639	biolink:NamedThing	benzoate catabolic process	The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.	got7fsn_ti	benzoate breakdown|benzoate catabolism|benzoate degradation													biological_process											owl:Class	
GO:0003002	biolink:NamedThing	regionalization	The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.	got7fsn_ti	pattern formation													biological_process											owl:Class	
GO:0036023	biolink:NamedThing	embryonic skeletal limb joint morphogenesis	The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.	got7fsn_ti							bf	2011-10-13T04:57:39Z						biological_process											owl:Class	
GO:0036022	biolink:NamedThing	limb joint morphogenesis	The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.	got7fsn_ti	knee morphogenesis|leg joint morphogenesis						bf	2011-10-13T04:52:59Z						biological_process											owl:Class	
GO:0097036	biolink:NamedThing	regulation of plasma membrane sterol distribution	Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane.	got7fsn_ti							pr	2011-04-08T02:08:08Z						biological_process											owl:Class	
GO:0033203	biolink:NamedThing	DNA helicase A complex	A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction.	got7fsn_ti														cellular_component											owl:Class	
GO:0039687	biolink:NamedThing	viral DNA strand displacement replication	A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).	got7fsn_ti							bf	2013-10-17T14:48:40Z				VZ:1940		biological_process											owl:Class	
GO:0009607	biolink:NamedThing	response to biotic stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.	got7fsn_ti	response to biotic stress				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0061638	biolink:NamedThing	CENP-A containing chromatin	The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.	got7fsn_ti	centromeric core region chromatin|centromeric core domain chromatin|chromatin containing CENP-A|nuclear CENP-A containing chromatin						dph	2014-08-20T14:06:35Z			GO:1904834			cellular_component											owl:Class	
GO:0000785	biolink:NamedThing	chromatin	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.	got7fsn_ti	cytoplasmic chromatin|nuclear chromatin|chromosome scaffold				Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.						GO:0000789|GO:0005717|GO:0000790	NIF_Subcellular:sao1615953555		cellular_component											owl:Class	
GO:0003948	biolink:NamedThing	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity	Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+).	got7fsn_ti	aspartylglucosaminidase activity|glycosylasparaginase activity|N-aspartyl-beta-glucosaminidase activity|beta-aspartylglucosylamine amidohydrolase activity|aspartylglucosylaminase activity|N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity|4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity|aspartylglucosylamine deaspartylase activity|aspartylglucosylaminidase activity|aspartylglycosylamine amidohydrolase activity|glucosylamidase activity											KEGG_REACTION:R03421|MetaCyc:3.5.1.26-RXN|EC:3.5.1.26|RHEA:11544		molecular_function											owl:Class	
GO:0047715	biolink:NamedThing	hypotaurocyamine kinase activity	Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H(+).	got7fsn_ti	ATP:hypotaurocyamine N-phosphotransferase activity											MetaCyc:HYPOTAUROCYAMINE-KINASE-RXN|RHEA:24008|EC:2.7.3.6|KEGG_REACTION:R03939		molecular_function											owl:Class	
GO:0005597	biolink:NamedThing	collagen type XVI trimer	A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0031339	biolink:NamedThing	negative regulation of vesicle fusion	Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.	got7fsn_ti	down-regulation of vesicle fusion|downregulation of vesicle fusion|inhibition of vesicle fusion|down regulation of vesicle fusion													biological_process											owl:Class	
GO:0031338	biolink:NamedThing	regulation of vesicle fusion	Any process that modulates the frequency, rate or extent of vesicle fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0036188	biolink:NamedThing	abieta-7,13-dien-18-al dehydrogenase activity	Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+.	got7fsn_ti	abietadienal dehydrogenase						bf	2012-04-18T01:46:19Z				KEGG_REACTION:R06357|EC:1.2.1.74|MetaCyc:1.2.1.74-RXN|RHEA:26225		molecular_function											owl:Class	
GO:0050734	biolink:NamedThing	hydroxycinnamoyltransferase activity	Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0042555	biolink:NamedThing	MCM complex	A hexameric protein complex required for the initiation and regulation of DNA replication.	got7fsn_ti	mini-chromosome maintenance complex													cellular_component											owl:Class	
GO:0006757	biolink:NamedThing	ATP generation from ADP	The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP.	got7fsn_ti	ADP phosphorylation													biological_process											owl:Class	
GO:0035249	biolink:NamedThing	synaptic transmission, glutamatergic	The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	got7fsn_ti	glutamatergic synaptic transmission													biological_process											owl:Class	
GO:0001525	biolink:NamedThing	angiogenesis	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.	got7fsn_ti	blood vessel formation from pre-existing blood vessels											Wikipedia:Angiogenesis		biological_process											owl:Class	
GO:0052918	biolink:NamedThing	dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.	got7fsn_ti												MetaCyc:RXN-5469|KEGG_REACTION:R06261|RHEA:29539|EC:2.4.1.261		molecular_function											owl:Class	
GO:0000026	biolink:NamedThing	alpha-1,2-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.	got7fsn_ti												Reactome:R-HSA-4551297|Reactome:R-HSA-446215|Reactome:R-HSA-446216|Reactome:R-HSA-9035514|Reactome:R-HSA-4720478|Reactome:R-HSA-446187		molecular_function											owl:Class	
GO:0016243	biolink:NamedThing	regulation of autophagosome size	Any process that modulates the size of the autophagosome.	got7fsn_ti	regulation of autophagic vacuole size													biological_process											owl:Class	
GO:1905037	biolink:NamedThing	autophagosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome.	got7fsn_ti	autophagic vacuole organization|initial autophagic vacuole organization						bf	2016-03-08T14:18:10Z						biological_process											owl:Class	
GO:0043772	biolink:NamedThing	acyl-phosphate glycerol-3-phosphate acyltransferase activity	Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate.	got7fsn_ti	acylphosphate glycerol-3-phosphate acyltransferase activity|acylphosphate:glycerol-3-phosphate acyltransferase activity|acyl-phosphate:glycerol-3-phosphate acyltransferase activity													molecular_function											owl:Class	
GO:0102058	biolink:NamedThing	jasmonoyl-leucine synthetase activity	Catalysis of the reaction: L-leucine  + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-leucine.	got7fsn_ti												MetaCyc:RXN-10459		molecular_function											owl:Class	
GO:0001654	biolink:NamedThing	eye development	The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.	got7fsn_ti											GO:0042460	Wikipedia:Eye_development		biological_process											owl:Class	
GO:0007423	biolink:NamedThing	sensory organ development	The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.	got7fsn_ti	sense organ development													biological_process											owl:Class	
GO:0097657	biolink:NamedThing	3',5'-nucleotide bisphosphate phosphatase activity	Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate.	got7fsn_ti							pr	2014-09-25T11:21:39Z				RHEA:43532|EC:3.1.3.97		molecular_function											owl:Class	
GO:0034862	biolink:NamedThing	2,6-dihydroxybenzothiazole monooxygenase activity	Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole.	got7fsn_ti												UM-BBD_reactionID:r1294		molecular_function											owl:Class	
GO:0016918	biolink:NamedThing	retinal binding	Binding to retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.	got7fsn_ti	red-sensitive opsin|vitamin A binding|violet-sensitive opsin|blue-sensitive opsin|opsin|long-wave-sensitive opsin|short-wave-sensitive opsin|retinaldehyde binding|green-sensitive opsin|UV-sensitive opsin													molecular_function											owl:Class	
GO:0047419	biolink:NamedThing	N-acetylgalactosamine-6-phosphate deacetylase activity	Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.	got7fsn_ti												RHEA:18149|EC:3.5.1.25|MetaCyc:3.5.1.80-RXN		molecular_function											owl:Class	
GO:0004744	biolink:NamedThing	retinal isomerase activity	Catalysis of the reaction: all-trans-retinal = 11-cis-retinal.	got7fsn_ti	all-trans-retinal 11-cis-trans-isomerase activity|retinoid isomerase activity|retinene isomerase activity											RHEA:24124|KEGG_REACTION:R02126|MetaCyc:RETINAL-ISOMERASE-RXN		molecular_function											owl:Class	
GO:0005834	biolink:NamedThing	heterotrimeric G-protein complex	Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein.	got7fsn_ti	heterotrimeric G-protein GTPase activity|heterotrimeric G-protein GTPase, alpha-subunit|heterotrimeric G-protein GTPase, beta-subunit|heterotrimeric G-protein GTPase, gamma-subunit				See also the molecular function term 'G protein-coupled receptor activity ; GO:0004930'.									cellular_component											owl:Class	
GO:0102705	biolink:NamedThing	serine decarboxylase activity	Catalysis of the reaction: H+ + L-serine  <=> ethanolaminium(1+) + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-5641|RHEA:45824		molecular_function											owl:Class	
GO:0070375	biolink:NamedThing	ERK5 cascade	An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.	got7fsn_ti	ERK5 signaling pathway|BMK1 cascade|BMK signalling pathway|extracellular signal-regulated kinase 5 cascade|BMK cascade|big MAP kinase signaling cascade|MAPK7 cascade|BMK signaling pathway													biological_process											owl:Class	
GO:0000165	biolink:NamedThing	MAPK cascade	An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.	got7fsn_ti	MAPK signal transduction|mitogen-activated protein kinase cascade|MAP kinase kinase kinase cascade|ERK/MAPK cascade|MAPK signalling|MAP kinase cascade|MAPK signaling|MAPKKK cascade|MAPKKK cascade during sporulation				MAPK cascades lie downstream of many cell surface receptors and cooperate in transmitting various extracellular signals to the nucleus. One way by which the specificity of each cascade is regulated is through the existence of several distinct components in each tier of the different cascades. The cascades are typically named according to the component in the MAPK tier.						GO:0007255	Wikipedia:MAPK_cascade|Wikipedia:Mitogen-activated_protein_kinase		biological_process											owl:Class	
GO:0090707	biolink:NamedThing	establishment of plant organ orientation	The process that determines the orientation of a plant organ or tissue with reference to an axis.	got7fsn_ti							tb	2016-10-05T12:42:47Z						biological_process											owl:Class	
GO:0098776	biolink:NamedThing	protein transport across the cell outer membrane	The directed movement of proteins across the cell outer membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0061580	biolink:NamedThing	colon epithelial cell migration	The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.	got7fsn_ti							dph	2013-12-23T07:26:54Z						biological_process											owl:Class	
GO:0061582	biolink:NamedThing	intestinal epithelial cell migration	The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.	got7fsn_ti							dph	2013-12-23T07:30:55Z						biological_process											owl:Class	
GO:0036143	biolink:NamedThing	kringle domain binding	Binding to a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.	got7fsn_ti							bf	2012-03-09T09:49:43Z						molecular_function											owl:Class	
GO:0009595	biolink:NamedThing	detection of biotic stimulus	The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.	got7fsn_ti	perception of biotic stimulus										GO:0009596			biological_process											owl:Class	
GO:0034928	biolink:NamedThing	1-hydroxypyrene 6,7-monooxygenase activity	Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O.	got7fsn_ti												UM-BBD_reactionID:r0946		molecular_function											owl:Class	
GO:0042538	biolink:NamedThing	hyperosmotic salinity response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti	salt tolerance|response to hyperosmotic salt stress													biological_process											owl:Class	
GO:0031813	biolink:NamedThing	P2Y2 nucleotide receptor binding	Binding to a P2Y2 nucleotide receptor.	got7fsn_ti	P2Y2 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0042622	biolink:NamedThing	photoreceptor outer segment membrane	The membrane surrounding the outer segment of a vertebrate photoreceptor.	got7fsn_ti														cellular_component											owl:Class	
GO:0060170	biolink:NamedThing	ciliary membrane	The portion of the plasma membrane surrounding a cilium.	got7fsn_ti	flagellum membrane|flagellar membrane|cilium membrane|cilial membrane				Note that cilia and eukaryotic flagella are deemed to be equivalent.						GO:0020017			cellular_component											owl:Class	
GO:0017087	biolink:NamedThing	mitochondrial processing peptidase complex	A protein complex consisting of a regulatory subunit (alpha-MPP) and a catalytic subunit (beta-MPP) that catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.	got7fsn_ti					Note that monomeric mitochondrial processing peptidases have been observed.									cellular_component											owl:Class	
GO:0004691	biolink:NamedThing	cAMP-dependent protein kinase activity	cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	got7fsn_ti	3',5' cAMP-dependent protein kinase activity|ATP:protein phosphotransferase (cAMP-dependent) activity|3',5'-cAMP-dependent protein kinase activity|cyclic AMP-dependent protein kinase activity|PKA|STK22|cAMP-dependent protein kinase, intrinsic catalyst activity|protein kinase A activity|AMPK|PKA C|adenosine 3',5'-cyclophosphate-dependent protein kinase activity				This reaction requires the presence of cAMP.						GO:0008602	Reactome:R-HSA-177275|Reactome:R-HSA-163672|Reactome:R-HSA-163676|Reactome:R-HSA-5610717|Reactome:R-HSA-5610720|Reactome:R-HSA-163773|Reactome:R-HSA-913451|Reactome:R-HSA-5687088|Reactome:R-HSA-5610741|EC:2.7.11.11|Reactome:R-HSA-5617179|Reactome:R-HSA-177284|Reactome:R-HSA-5617182|Reactome:R-HSA-432232|MetaCyc:2.7.11.11-RXN		molecular_function											owl:Class	
GO:0004690	biolink:NamedThing	cyclic nucleotide-dependent protein kinase activity	cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	got7fsn_ti					This reaction requires the presence of a cyclic nucleotide.									molecular_function											owl:Class	
GO:0097323	biolink:NamedThing	B cell adhesion	The attachment of a B cell to another cell via adhesion molecules.	got7fsn_ti							pr	2012-06-06T01:59:19Z						biological_process											owl:Class	
GO:0060008	biolink:NamedThing	Sertoli cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.	got7fsn_ti														biological_process											owl:Class	
GO:1990836	biolink:NamedThing	lysosomal matrix	A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome.	got7fsn_ti							sl	2015-08-25T17:04:12Z						cellular_component											owl:Class	
GO:0047941	biolink:NamedThing	glucuronolactone reductase activity	Catalysis of the reaction: L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + H(+) + NADPH.	got7fsn_ti												KEGG_REACTION:R03183|MetaCyc:GLUCURONOLACTONE-REDUCTASE-RXN|EC:1.1.1.20|RHEA:18925		molecular_function											owl:Class	
GO:0075183	biolink:NamedThing	infection cushion formation	The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass.	got7fsn_ti	infection cushion formation on or near host													biological_process											owl:Class	
GO:0097359	biolink:NamedThing	UDP-glucosylation	The covalent attachment of a UDP-glucose residue to a substrate molecule.	got7fsn_ti							pr	2012-07-06T02:26:35Z						biological_process											owl:Class	
GO:0006011	biolink:NamedThing	UDP-glucose metabolic process	The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-glucose metabolism													biological_process											owl:Class	
GO:0048309	biolink:NamedThing	endoplasmic reticulum inheritance	The partitioning of endoplasmic reticulum between daughter cells at cell division.	got7fsn_ti	ER inheritance													biological_process											owl:Class	
GO:0043178	biolink:NamedThing	alcohol binding	Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.	got7fsn_ti														molecular_function											owl:Class	
GO:1990605	biolink:NamedThing	GU repeat RNA binding	Binding to an RNA molecule containing GU repeats.	got7fsn_ti							al	2015-01-13T18:18:01Z						molecular_function											owl:Class	
GO:0018639	biolink:NamedThing	xylene monooxygenase activity	Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol.	got7fsn_ti												UM-BBD_enzymeID:e0172|EC:1.14.13.-		molecular_function											owl:Class	
GO:0018306	biolink:NamedThing	iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulphide											RESID:AA0289		biological_process											owl:Class	
GO:0018283	biolink:NamedThing	iron incorporation into metallo-sulfur cluster	The incorporation of iron into a metallo-sulfur cluster.	got7fsn_ti	iron incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0017194	biolink:NamedThing	N-terminal peptidyl-isoleucine acetylation	The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed.	got7fsn_ti												RESID:AA0047		biological_process											owl:Class	
GO:0035525	biolink:NamedThing	NF-kappaB p50/p65 complex	A heterodimer of NF-kappa B p50 and p65 subunits.	got7fsn_ti	NF-kappa p105/RelA complex|NF-kappa B1/RelA complex|NF-kappa p50/RelA complex|NF-kappa B1/p65 complex|NF-kappa p105/p65 complex				Note that the p50 subunit is encoded by NFKB1 gene in human and the p65 subunit is encoded by the RELA gene in human. Similar nomenclature is used in other vertebrate species. The p50 subunit has a precursor form p105 in some publications.		bf	2010-05-05T10:45:13Z						cellular_component											owl:Class	
GO:0071159	biolink:NamedThing	NF-kappaB complex	A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression.	got7fsn_ti							mah	2009-11-17T02:03:34Z						cellular_component											owl:Class	
GO:0034549	biolink:NamedThing	N-cyclopropylammelide alkylamino hydrolase activity	Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid.	got7fsn_ti												UM-BBD_reactionID:r0827|KEGG_REACTION:R06972|MetaCyc:RXN-8020		molecular_function											owl:Class	
GO:0048262	biolink:NamedThing	determination of dorsal/ventral asymmetry	Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.	got7fsn_ti	determination of adaxial/abaxial asymmetry|determination of dorsal-ventral asymmetry|determination of dorsoventral asymmetry													biological_process											owl:Class	
GO:0062082	biolink:NamedThing	HLA-E specific inhibitory MHC class Ib receptor activity	Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.	got7fsn_ti							dph	2018-10-15T15:06:22Z						molecular_function											owl:Class	
GO:0062080	biolink:NamedThing	inhibitory MHC class Ib receptor activity	Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte.	got7fsn_ti							dph	2018-10-15T15:03:44Z						molecular_function											owl:Class	
GO:0046558	biolink:NamedThing	arabinan endo-1,5-alpha-L-arabinosidase activity	Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans.	got7fsn_ti	1,5-alpha-L-arabinan 1,5-alpha-L-arabinanohydrolase activity|endo-arabanase activity|endo-1,5-alpha-L-arabinanase activity|endo-alpha-1,5-arabanase activity											MetaCyc:3.2.1.99-RXN|EC:3.2.1.99		molecular_function											owl:Class	
GO:0044529	biolink:NamedThing	regulation of mitochondrial rRNA stability	Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs.	got7fsn_ti							jl	2012-03-15T03:22:19Z						biological_process											owl:Class	
GO:0044357	biolink:NamedThing	regulation of rRNA stability	Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs.	got7fsn_ti	regulation of ribosomal RNA stability						jl	2011-08-31T09:57:54Z						biological_process											owl:Class	
GO:1990427	biolink:NamedThing	stereocilia tip-link density	An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane.	got7fsn_ti							sl	2014-07-25T20:55:36Z						cellular_component											owl:Class	
GO:0101012	biolink:NamedThing	inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate 1-diphosphatase activity	Catalysis of the reaction: myo-inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate + H2O = myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate.	got7fsn_ti	inositol 1,5-bispyrophosphate 2,3,4,6-tetrakisphosphate 1-pyrophosphatase activity													molecular_function											owl:Class	
GO:0003348	biolink:NamedThing	cardiac endothelial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.	got7fsn_ti							dph	2009-12-01T11:12:05Z						biological_process											owl:Class	
GO:0035051	biolink:NamedThing	cardiocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.	got7fsn_ti	cardiac cell differentiation|heart cell differentiation													biological_process											owl:Class	
GO:0042393	biolink:NamedThing	histone binding	Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.	got7fsn_ti	histone-specific chaperone activity													molecular_function											owl:Class	
GO:0000009	biolink:NamedThing	alpha-1,6-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.	got7fsn_ti	1,6-alpha-mannosyltransferase activity											Reactome:R-HSA-449718|EC:2.4.1.232		molecular_function											owl:Class	
GO:0140065	biolink:NamedThing	peptide butyryltransferase activity	Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.	got7fsn_ti	protein butyryltransferase activity						pg	2017-07-20T16:46:49Z						molecular_function											owl:Class	
GO:0097490	biolink:NamedThing	sympathetic neuron projection extension	Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	got7fsn_ti	sympathetic neuron protrusion extension|sympathetic neurite extension|sympathetic neuron process extension|sympathetic neuronal cell projection extension						pr	2013-07-10T11:47:53Z						biological_process											owl:Class	
GO:1990138	biolink:NamedThing	neuron projection extension	Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	got7fsn_ti	neurite extension|neuron protrusion extension|neuronal cell projection extension|neuron process extension						pr	2013-07-08T08:40:45Z						biological_process											owl:Class	
GO:0090534	biolink:NamedThing	calcium ion-transporting ATPase complex	Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in).	got7fsn_ti							tb	2013-02-07T15:52:58Z						cellular_component											owl:Class	
GO:0090533	biolink:NamedThing	cation-transporting ATPase complex	Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).	got7fsn_ti							tb	2013-02-07T15:50:28Z						cellular_component											owl:Class	
GO:0044544	biolink:NamedThing	envenomation resulting in plasminogen activation in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.	got7fsn_ti							jl	2012-03-22T11:54:49Z						biological_process											owl:Class	
GO:0044484	biolink:NamedThing	envenomation resulting in fibrinolysis in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism.	got7fsn_ti							jl	2012-01-26T03:26:33Z						biological_process											owl:Class	
GO:0003950	biolink:NamedThing	NAD+ ADP-ribosyltransferase activity	Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.	got7fsn_ti	poly(ADP-ribose)polymerase activity|NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|poly(ADP-ribose) synthetase activity|poly(ADP-ribose) synthase activity|ADP-ribosyltransferase (polymerizing) activity|NAD ADP-ribosyltransferase activity|poly(adenosine diphosphate ribose) polymerase activity											Reactome:R-HSA-5687653|MetaCyc:NAD+-ADP-RIBOSYLTRANSFERASE-RXN|EC:2.4.2.30|Reactome:R-HSA-5688276|Reactome:R-HSA-8938073|Reactome:R-HSA-2187325|Reactome:R-HSA-5651723|Reactome:R-HSA-9686061|Reactome:R-HSA-8948800|Reactome:R-HSA-9694773|Reactome:R-HSA-3640858		molecular_function											owl:Class	
GO:0018792	biolink:NamedThing	bis(4-chlorophenyl)acetate decarboxylase activity	Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.	got7fsn_ti	DDA decarboxylase activity											UM-BBD_reactionID:r0520		molecular_function											owl:Class	
GO:0060141	biolink:NamedThing	positive regulation of syncytium formation by virus	The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	got7fsn_ti	syncytium formation induced by viral infection													biological_process											owl:Class	
GO:0060140	biolink:NamedThing	modulation by virus of syncytium formation via plasma membrane fusion	The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0030986	biolink:NamedThing	low molecular weight kininogen binding	Binding to a kininogen of low molecular mass.	got7fsn_ti	LMW kininogen binding|LK binding													molecular_function											owl:Class	
GO:0030984	biolink:NamedThing	kininogen binding	Binding to a kininogen, a kinin precursor.	got7fsn_ti														molecular_function											owl:Class	
GO:0006767	biolink:NamedThing	water-soluble vitamin metabolic process	The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water.	got7fsn_ti	water-soluble vitamin metabolism													biological_process											owl:Class	
GO:0061674	biolink:NamedThing	gap filling involved in double-strand break repair via nonhomologous end joining	Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining.	got7fsn_ti							dph	2015-01-05T10:07:32Z						biological_process											owl:Class	
GO:0021699	biolink:NamedThing	cerebellar cortex maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	got7fsn_ti														biological_process											owl:Class	
GO:0043303	biolink:NamedThing	mast cell degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.	got7fsn_ti	mast cell granule exocytosis	https://github.com/geneontology/go-ontology/issues/15943												biological_process											owl:Class	
GO:0019601	biolink:NamedThing	toluene oxidation via 2-hydroxytoluene	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol).	got7fsn_ti												MetaCyc:TOLUENE-DEG-2-OH-PWY		biological_process											owl:Class	
GO:0006471	biolink:NamedThing	protein ADP-ribosylation	The transfer, from NAD, of ADP-ribose to protein amino acids.	got7fsn_ti	protein amino acid ADP-ribosylation											RESID:AA0040|RESID:AA0231|RESID:AA0295|RESID:AA0169|RESID:AA0237|RESID:AA0168		biological_process											owl:Class	
GO:0018313	biolink:NamedThing	peptide cross-linking via L-alanyl-5-imidazolinone glycine	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.	got7fsn_ti												RESID:AA0187		biological_process											owl:Class	
GO:0018253	biolink:NamedThing	peptide cross-linking via 5-imidazolinone glycine	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde.	got7fsn_ti	biosynthesis of protein-protein cross-link via 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 5-imidazolinone glycine											RESID:AA0187|RESID:AA0184|RESID:AA0188		biological_process											owl:Class	
GO:0002485	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.	got7fsn_ti	TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway|TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway|endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent													biological_process											owl:Class	
GO:0002484	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class I via ER pathway													biological_process											owl:Class	
GO:0102035	biolink:NamedThing	isobutyryl-CoA:FAD oxidoreductase activity	Catalysis of the reaction: H+ + isobutyryl-CoA + FAD <=> methacrylyl-CoA + FADH2.	got7fsn_ti												EC:1.3.8.5|MetaCyc:MEPROPCOA-FAD-RXN		molecular_function											owl:Class	
GO:0048235	biolink:NamedThing	pollen sperm cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.	got7fsn_ti	sperm cell differentiation|male gamete generation|male gametophyte sperm cell differentiation										GO:0048234			biological_process											owl:Class	
GO:0005229	biolink:NamedThing	intracellular calcium activated chloride channel activity	Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	got7fsn_ti												Reactome:R-HSA-2744242|Reactome:R-HSA-9659568|Reactome:R-HSA-2744361|Reactome:R-HSA-2684901		molecular_function											owl:Class	
GO:0036153	biolink:NamedThing	triglyceride acyl-chain remodeling	Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.	got7fsn_ti	triacylglycerol acyl-chain remodeling						bf	2012-03-14T02:49:05Z						biological_process											owl:Class	
GO:0036155	biolink:NamedThing	acylglycerol acyl-chain remodeling	Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.	got7fsn_ti	glyceride acyl-chain remodeling						bf	2012-03-14T02:55:00Z						biological_process											owl:Class	
GO:0045481	biolink:NamedThing	6-endo-hydroxycineole dehydrogenase activity	Catalysis of the reaction: 6-endo-hydroxycineole + NAD(+) = 6-oxocineole + H(+) + NADH.	got7fsn_ti	6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity											EC:1.1.1.241|KEGG_REACTION:R02994|MetaCyc:6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN|RHEA:11736		molecular_function											owl:Class	
GO:0010500	biolink:NamedThing	transmitting tissue development	The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.	got7fsn_ti														biological_process											owl:Class	
GO:0048467	biolink:NamedThing	gynoecium development	The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.	got7fsn_ti	pistil development													biological_process											owl:Class	
GO:0051742	biolink:NamedThing	2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine.	got7fsn_ti	MSBQ methyltransferase activity											MetaCyc:RXN-2762|RHEA:37999		molecular_function											owl:Class	
GO:0005289	biolink:NamedThing	high-affinity arginine transmembrane transporter activity	Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high-affinity arginine transporter activity|high affinity arginine transmembrane transporter activity													molecular_function											owl:Class	
GO:0008767	biolink:NamedThing	UDP-galactopyranose mutase activity	Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.	got7fsn_ti	UDPgalactopyranose mutase activity|UDP-D-galactopyranose furanomutase activity											RHEA:24132|EC:5.4.99.9|MetaCyc:GALPMUT-RXN		molecular_function											owl:Class	
GO:0016866	biolink:NamedThing	intramolecular transferase activity	Catalysis of the transfer of a functional group from one position to another within a single molecule.	got7fsn_ti	mutase activity|intramolecular transferase activity, transferring other groups											EC:5.4.-.-		molecular_function											owl:Class	
GO:0099703	biolink:NamedThing	induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration	The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse.  This is the first step in synaptic transmission.	got7fsn_ti														biological_process											owl:Class	
GO:0099533	biolink:NamedThing	positive regulation of presynaptic cytosolic calcium concentration	Any process that increases the concentration of calcium ions in the presynaptic cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:0036437	biolink:NamedThing	Isw1b complex	An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p.	got7fsn_ti							bf	2013-09-18T16:53:07Z						cellular_component											owl:Class	
GO:0016587	biolink:NamedThing	Isw1 complex	A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure.	got7fsn_ti														cellular_component											owl:Class	
GO:0007087	biolink:NamedThing	mitotic nuclear pore complex reassembly	The cell cycle process in which nuclear pore complexes reform during mitotic cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0006900	biolink:NamedThing	vesicle budding from membrane	The evagination of a membrane, resulting in formation of a vesicle.	got7fsn_ti	nonselective vesicle assembly|membrane evagination|single-organism membrane budding|vesicle biosynthesis|vesicle formation|vesicle budding|single organism membrane budding						jl	2013-12-19T15:26:17Z			GO:0006902|GO:1902591			biological_process											owl:Class	
GO:0016050	biolink:NamedThing	vesicle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.	got7fsn_ti	vesicle organisation|vesicle organization and biogenesis													biological_process											owl:Class	
GO:0001194	biolink:NamedThing	maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a bacterial-type RNA polymerase promoter.	got7fsn_ti	maintenance of transcriptional fidelity during DNA-dependent transcription elongation from bacterial-type RNA polymerase promoter						krc	2011-09-02T02:37:59Z						biological_process											owl:Class	
GO:0018625	biolink:NamedThing	naphthalene 1,2-dioxygenase activity	Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+.	got7fsn_ti	naphthalene dioxygenase activity|naphthalene oxygenase activity|naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)											EC:1.14.12.12|RHEA:19173|UM-BBD_enzymeID:e0002|MetaCyc:NAPHTHALENE-12-DIOXYGENASE-RXN		molecular_function											owl:Class	
GO:0075733	biolink:NamedThing	intracellular transport of virus	The directed movement of a virus, or part of a virus, within the host cell.	got7fsn_ti	egress of virus within host cell|movement of virus within host cell|viral genome transport in host cell|intracellular transport of viral material|intracellular virion transport|viral egress						jl	2009-05-01T04:01:33Z			GO:0046788|GO:0046795|GO:0046796			biological_process											owl:Class	
GO:0047805	biolink:NamedThing	cytidylate cyclase activity	Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+).	got7fsn_ti	cytidylyl cyclase activity|cytidyl cyclase activity|3'5'-cyclic-CMP synthase activity|CTP diphosphate-lyase (cyclizing)|CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)|3',5'-cyclic-CMP synthase activity											MetaCyc:CYTIDYLATE-CYCLASE-RXN|KEGG_REACTION:R00574|RHEA:14737|EC:4.6.1.6		molecular_function											owl:Class	
GO:1990946	biolink:NamedThing	meiosis I/meiosis II transition	The cell cycle process in which a cell progresses from meiosis I to meiosis II.	got7fsn_ti							vw	2016-04-21T13:01:07Z						biological_process											owl:Class	
GO:0044771	biolink:NamedThing	meiotic cell cycle phase transition	The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase.	got7fsn_ti	cell cycle transition						jl	2013-02-28T13:08:17Z						biological_process											owl:Class	
GO:0048367	biolink:NamedThing	shoot system development	The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.	got7fsn_ti	shoot development										GO:0022621			biological_process											owl:Class	
GO:0051523	biolink:NamedThing	cell growth mode switching, monopolar to bipolar	The process in which a cell switches from monopolar cell growth to bipolar cell growth.	got7fsn_ti	NETO|new end take off													biological_process											owl:Class	
GO:0061171	biolink:NamedThing	establishment of bipolar cell polarity	The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.	got7fsn_ti							dph	2010-06-30T08:49:38Z						biological_process											owl:Class	
GO:0015544	biolink:NamedThing	phenyl propionate uniporter activity	Enables the transfer of phenyl propionate from one side of a membrane to the other.	got7fsn_ti	phenyl propionate permease activity													molecular_function											owl:Class	
GO:0015292	biolink:NamedThing	uniporter activity	Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species.	got7fsn_ti	single-species transporter activity|facilitated diffusion carrier|uniport													molecular_function											owl:Class	
GO:0075054	biolink:NamedThing	modulation of penetration peg formation	Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of symbiont penetration peg initiation|modulation of symbiont penetration peg formation for entry into host	https://github.com/geneontology/go-ontology/issues/18557			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.						GO:0075058			biological_process											owl:Class	
GO:0052372	biolink:NamedThing	modulation by symbiont of entry into host	Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation by organism of entry into other organism during symbiotic interaction|modulation by symbiont of entry into host|regulation by organism of entry into other organism involved in symbiotic interaction|regulation by organism of entry into other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/19027									GO:0052371			biological_process											owl:Class	
GO:0030642	biolink:NamedThing	cellular sulfate ion homeostasis	Any process involved in the maintenance of an internal steady state of sulfate ions at the level of a cell.	got7fsn_ti	sulphate ion homeostasis													biological_process											owl:Class	
GO:0039556	biolink:NamedThing	MDA-5 binding	Binding to MDA-5, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA.	got7fsn_ti	MDA5 binding						bf	2012-03-09T04:12:33Z						molecular_function											owl:Class	
GO:0002512	biolink:NamedThing	central T cell tolerance induction	Tolerance induction of T cells in the thymus.	got7fsn_ti	central T-cell tolerance induction|central T-lymphocyte tolerance induction|central T lymphocyte tolerance induction													biological_process											owl:Class	
GO:0006058	biolink:NamedThing	mannoprotein catabolic process	The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues.	got7fsn_ti	mannoprotein degradation|mannoprotein catabolism|mannoprotein breakdown													biological_process											owl:Class	
GO:0006516	biolink:NamedThing	glycoprotein catabolic process	The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	got7fsn_ti	glycoprotein catabolism|glycoprotein degradation|glycoprotein breakdown													biological_process											owl:Class	
GO:0004356	biolink:NamedThing	glutamate-ammonia ligase activity	Catalysis of the reaction: L-glutamate + ATP + NH(3) = L-glutamine + ADP + 2 H(+) + phosphate.	got7fsn_ti	glutamylhydroxamic synthetase activity|L-glutamine synthetase activity|glutamine synthetase activity|L-glutamate:ammonia ligase (ADP-forming)											Reactome:R-HSA-70606|KEGG_REACTION:R00253|MetaCyc:GLUTAMINESYN-RXN|EC:6.3.1.2|RHEA:16169		molecular_function											owl:Class	
GO:0016211	biolink:NamedThing	ammonia ligase activity	Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.	got7fsn_ti												EC:6.3.1.-		molecular_function											owl:Class	
GO:0008113	biolink:NamedThing	peptide-methionine (S)-S-oxide reductase activity	Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.	got7fsn_ti	peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity|methionine S-oxide reductase (S-form oxidizing) activity|MsrA|methionine sulphoxide reductase A activity|peptide-methionine-(S)-S-oxide reductase activity|peptide Met(O) reductase activity|protein-methionine-S-oxide reductase activity|methionine sulfoxide (protein) reductase activity|methionine sulfoxide reductase activity|peptide methionine sulfoxide reductase activity|methionine sulfoxide reductase A activity|methionine S-oxide reductase activity										GO:0033742|GO:0072561	Reactome:R-HSA-1222363|RHEA:14217|MetaCyc:RXN-8668|Reactome:R-HSA-5676940|MetaCyc:RXN-8669|EC:1.8.4.11		molecular_function											owl:Class	
GO:0004398	biolink:NamedThing	histidine decarboxylase activity	Catalysis of the reaction: L-histidine = histamine + CO2.	got7fsn_ti	L-histidine decarboxylase activity|L-histidine carboxy-lyase (histamine-forming)|L-histidine carboxy-lyase activity											EC:4.1.1.22|Reactome:R-HSA-977301|RHEA:20840|MetaCyc:HISTIDINE-DECARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0042285	biolink:NamedThing	xylosyltransferase activity	Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0045807	biolink:NamedThing	positive regulation of endocytosis	Any process that activates or increases the frequency, rate or extent of endocytosis.	got7fsn_ti	up regulation of endocytosis|up-regulation of endocytosis|stimulation of endocytosis|activation of endocytosis|upregulation of endocytosis													biological_process											owl:Class	
GO:0071476	biolink:NamedThing	cellular hypotonic response	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.	got7fsn_ti	cellular hypo-osmotic response						mah	2009-12-18T11:52:59Z						biological_process											owl:Class	
GO:0018500	biolink:NamedThing	trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity	Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene.	got7fsn_ti												UM-BBD_reactionID:r0575		molecular_function											owl:Class	
GO:0002931	biolink:NamedThing	response to ischemia	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.	got7fsn_ti					Ischemia always results in hypoxia; however, hypoxia can occur without ischemia.		hjd	2012-04-20T02:57:51Z						biological_process											owl:Class	
GO:0030678	biolink:NamedThing	mitochondrial ribonuclease P complex	A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species. The complex contains a single RNA molecule and a single protein molecule in yeast (PMID:12045094), but comprises three proteins and lacks an RNA component in humans.	got7fsn_ti	mitochondrial RNase P complex	https://github.com/geneontology/go-ontology/issues/20778												cellular_component											owl:Class	
GO:0008654	biolink:NamedThing	phospholipid biosynthetic process	The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.	got7fsn_ti	phospholipid synthesis|phospholipid biosynthesis|phospholipid formation|phospholipid anabolism											MetaCyc:PHOSLIPSYN-PWY|MetaCyc:LIPASYN-PWY|MetaCyc:PHOSLIPSYN2-PWY		biological_process											owl:Class	
GO:0050934	biolink:NamedThing	late stripe melanocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).	got7fsn_ti	late stripe melanocyte cell differentiation|late stripe melanophore differentiation													biological_process											owl:Class	
GO:0030318	biolink:NamedThing	melanocyte differentiation	The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.	got7fsn_ti	melanophore differentiation|melanocyte cell differentiation													biological_process											owl:Class	
GO:0071483	biolink:NamedThing	cellular response to blue light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.	got7fsn_ti	cellular response to blue light stimulus						mah	2009-12-18T02:09:48Z						biological_process											owl:Class	
GO:0018167	biolink:NamedThing	protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine	The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.	got7fsn_ti												RESID:AA0259		biological_process											owl:Class	
GO:0017011	biolink:NamedThing	protein-phycoerythrobilin linkage	The linkage of the chromophore phycoerythrobilin to phycoerythrins.	got7fsn_ti												RESID:AA0132		biological_process											owl:Class	
GO:0008742	biolink:NamedThing	L-ribulose-phosphate 4-epimerase activity	Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate.	got7fsn_ti	L-ribulose 5-phosphate 4-epimerase activity|phosphoribulose isomerase activity|ribulose phosphate 4-epimerase activity|L-ribulose-5-phosphate 4-epimerase|L-ru5P activity|AraD|L-Ru5P											EC:5.1.3.4|MetaCyc:RIBULPEPIM-RXN|RHEA:22368|KEGG_REACTION:R05850		molecular_function											owl:Class	
GO:0033952	biolink:NamedThing	iota-carrageenase activity	Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans.	got7fsn_ti	iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting) activity											MetaCyc:3.2.1.157-RXN|EC:3.2.1.157		molecular_function											owl:Class	
GO:0047149	biolink:NamedThing	thetin-homocysteine S-methyltransferase activity	Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H(+).	got7fsn_ti	thetin-homocysteine methylpherase activity|dimethylthetin-homocysteine methyltransferase activity|dimethylsulfonioacetate:L-homocysteine S-methyltransferase activity											KEGG_REACTION:R04153|EC:2.1.1.3|RHEA:22788|MetaCyc:2.1.1.3-RXN		molecular_function											owl:Class	
GO:0051962	biolink:NamedThing	positive regulation of nervous system development	Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.	got7fsn_ti	up regulation of nervous system development|up-regulation of nervous system development|upregulation of nervous system development|activation of nervous system development|stimulation of nervous system development													biological_process											owl:Class	
GO:0043430	biolink:NamedThing	2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	got7fsn_ti	2-decaprenyl-6-methoxy-1,4-benzoquinone methylase activity				Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.							RHEA:44764|Reactome:R-HSA-2162188		molecular_function											owl:Class	
GO:0035601	biolink:NamedThing	protein deacylation	The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.	got7fsn_ti	protein amino acid deacylation						bf	2010-11-15T11:06:15Z						biological_process											owl:Class	
GO:0098732	biolink:NamedThing	macromolecule deacylation	The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.	got7fsn_ti														biological_process											owl:Class	
GO:0036308	biolink:NamedThing	16S rRNA (guanine(1516)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine.	got7fsn_ti							bf	2012-08-08T14:17:44Z						molecular_function											owl:Class	
GO:0008990	biolink:NamedThing	rRNA (guanine-N2-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine.	got7fsn_ti	ribosomal ribonucleate guanine-2-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-2-N-)-methyltransferase activity											EC:2.1.1.52|MetaCyc:RRNA-GUANINE-N2--METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0043424	biolink:NamedThing	protein histidine kinase binding	Binding to a protein histidine kinase.	got7fsn_ti	histidine-protein kinase binding|histidine kinase binding|protein-histidine kinase binding													molecular_function											owl:Class	
GO:0043175	biolink:NamedThing	RNA polymerase core enzyme binding	Binding to an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.	got7fsn_ti														molecular_function											owl:Class	
GO:0070063	biolink:NamedThing	RNA polymerase binding	Binding to an RNA polymerase molecule or complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0003191	biolink:NamedThing	coronary sinus valve formation	The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti							dph	2009-10-08T01:09:04Z						biological_process											owl:Class	
GO:0003188	biolink:NamedThing	heart valve formation	The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti							dph	2009-10-08T12:20:15Z						biological_process											owl:Class	
GO:0008853	biolink:NamedThing	exodeoxyribonuclease III activity	Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides.	got7fsn_ti	Escherichia coli exonuclease III|E. coli exonuclease III activity|exonuclease III activity|E. coli exonuclease III|endoribonuclease III											MetaCyc:3.1.11.2-RXN|EC:3.1.11.2		molecular_function											owl:Class	
GO:0016895	biolink:NamedThing	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.	got7fsn_ti	exonuclease VIII activity|exodeoxyribonuclease activity, producing 5' phosphomonoesters										GO:0008858	EC:3.1.11.-		molecular_function											owl:Class	
GO:0060875	biolink:NamedThing	lateral semicircular canal development	The progession of the lateral semicircular canal from its initial formation to the mature structure.	got7fsn_ti							dph	2009-08-13T09:43:25Z						biological_process											owl:Class	
GO:0060872	biolink:NamedThing	semicircular canal development	The progression of the semicircular canal from its initial formation to the mature structure.	got7fsn_ti							dph	2009-08-13T09:36:37Z						biological_process											owl:Class	
GO:0016995	biolink:NamedThing	cholesterol oxidase activity	Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2.	got7fsn_ti	3beta-hydroxy steroid oxidoreductase activity|cholesterol-O2 oxidoreductase activity|cholesterol- O2 oxidoreductase activity|3beta-hydroxysteroid:oxygen oxidoreductase activity|cholesterol-O(2) oxidoreductase activity|cholesterol:oxygen oxidoreductase activity											MetaCyc:CHOLESTEROL-OXIDASE-RXN|EC:1.1.3.6|RHEA:32183|KEGG_REACTION:R01459		molecular_function											owl:Class	
GO:0060204	biolink:NamedThing	clathrin-sculpted glutamate transport vesicle lumen	The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle.	got7fsn_ti	clathrin sculpted glutamate transport vesicle lumen|clathrin sculpted glutamate constitutive secretory pathway transport vesicle lumen													cellular_component											owl:Class	
GO:0036150	biolink:NamedThing	phosphatidylserine acyl-chain remodeling	Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.	got7fsn_ti	phosphatidyl-L-serine acyl-chain remodeling						bf	2012-03-14T01:35:44Z						biological_process											owl:Class	
GO:0006658	biolink:NamedThing	phosphatidylserine metabolic process	The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.	got7fsn_ti	phosphatidylserine metabolism													biological_process											owl:Class	
GO:0050001	biolink:NamedThing	D-glutaminase activity	Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate.	got7fsn_ti	D-glutamine amidohydrolase activity											EC:3.5.1.35|MetaCyc:D-GLUTAMINASE-RXN|RHEA:22840		molecular_function											owl:Class	
GO:0018244	biolink:NamedThing	protein N-linked glycosylation via tryptophan	The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue.	got7fsn_ti	protein amino acid N-linked glycosylation via tryptophan											RESID:AA0156		biological_process											owl:Class	
GO:0018211	biolink:NamedThing	peptidyl-tryptophan modification	The chemical alteration of a tryptophan residue in a peptide.	got7fsn_ti														biological_process											owl:Class	
GO:0106366	biolink:NamedThing	guanosine kinase activity	Catalysis of the reaction: ATP + guanosine = ADP + GMP.	got7fsn_ti							hjd	2021-02-23T21:18:12Z				RHEA:27710|EC:2.7.1.73		molecular_function											owl:Class	
GO:0005633	biolink:NamedThing	ascus lipid droplet	Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins.	got7fsn_ti	ascus lipid particle													cellular_component											owl:Class	
GO:0005811	biolink:NamedThing	lipid droplet	An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.	got7fsn_ti	lipid body|adiposome|lipid particle				Note that this term does not refer to vesicles, but instead to structures in which lipids do not necessarily form bilayers.									cellular_component											owl:Class	
GO:0014815	biolink:NamedThing	initiation of skeletal muscle satellite cell activation by growth factor signaling, involved in skeletal muscle regeneration	Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.	got7fsn_ti														biological_process											owl:Class	
GO:0014718	biolink:NamedThing	positive regulation of satellite cell activation involved in skeletal muscle regeneration	Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.	got7fsn_ti														biological_process											owl:Class	
GO:0048677	biolink:NamedThing	axon extension involved in regeneration	Long distance growth of a single axon process involved in regeneration of the neuron.	got7fsn_ti														biological_process											owl:Class	
GO:0048682	biolink:NamedThing	sprouting of injured axon	The process involved in sprouting of an injured axon.	got7fsn_ti														biological_process											owl:Class	
GO:0052173	biolink:NamedThing	response to defenses of other organism	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism.	got7fsn_ti	response to defenses of other organism during symbiotic interaction|response to defenses of other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/17930												biological_process											owl:Class	
GO:0018791	biolink:NamedThing	2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity	Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate.	got7fsn_ti												UM-BBD_reactionID:r0398		molecular_function											owl:Class	
GO:0047775	biolink:NamedThing	citramalate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA.	got7fsn_ti	acetyl-CoA:citramalate CoA-transferase activity											MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN|RHEA:17621|EC:2.8.3.11		molecular_function											owl:Class	
GO:0008410	biolink:NamedThing	CoA-transferase activity	Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor).	got7fsn_ti												Reactome:R-HSA-70713|EC:2.8.3.-		molecular_function											owl:Class	
GO:0007446	biolink:NamedThing	imaginal disc growth	The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.	got7fsn_ti														biological_process											owl:Class	
GO:0060388	biolink:NamedThing	vitelline envelope	A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.	got7fsn_ti	fertilization membrane													cellular_component											owl:Class	
GO:0035805	biolink:NamedThing	egg coat	A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.	got7fsn_ti	zona pellucida|vitelline membrane						bf	2011-04-19T02:07:23Z						cellular_component											owl:Class	
GO:0018045	biolink:NamedThing	C-terminal peptidyl-lysine amidation	The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0092		biological_process											owl:Class	
GO:0033179	biolink:NamedThing	proton-transporting V-type ATPase, V0 domain	A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring.	got7fsn_ti														cellular_component											owl:Class	
GO:0072763	biolink:NamedThing	cellular response to hesperadin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.	got7fsn_ti							mah	2012-11-09T11:50:58Z						biological_process											owl:Class	
GO:1901595	biolink:NamedThing	response to hesperadin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.	got7fsn_ti							mah	2012-11-07T17:16:57Z						biological_process											owl:Class	
GO:0044193	biolink:NamedThing	host cell mitochondrial outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the host cell mitochondrial envelope.	got7fsn_ti							jl	2009-10-15T04:18:44Z						cellular_component											owl:Class	
GO:0039661	biolink:NamedThing	host organelle outer membrane	The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell.	got7fsn_ti							bf	2013-08-25T10:44:43Z						cellular_component											owl:Class	
GO:0034282	biolink:NamedThing	ent-pimara-8(14),15-diene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate.	got7fsn_ti	ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-8(14),15-diene-forming] activity|ent-pimaradiene synthase activity											RHEA:25540|EC:4.2.3.30|MetaCyc:RXN-7788|KEGG_REACTION:R09121		molecular_function											owl:Class	
GO:0044654	biolink:NamedThing	starch alpha-glucosidase activity	Catalysis of the reaction: starch + H2O = alpha-D-glucose.	got7fsn_ti							jl	2012-07-23T02:08:10Z				EC:3.2.1.-		molecular_function											owl:Class	
GO:0090599	biolink:NamedThing	alpha-glucosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.	got7fsn_ti							tb	2014-08-22T14:33:31Z				EC:3.2.1.20|Reactome:R-HSA-9036729|Reactome:R-HSA-9036727		molecular_function											owl:Class	
GO:0055096	biolink:NamedThing	low-density lipoprotein particle mediated signaling	A series of molecular signals mediated by the detection of low-density lipoprotein particle.	got7fsn_ti	low-density lipoprotein particle-mediated signaling|low-density lipoprotein particle mediated signal transduction|low-density lipoprotein mediated signalling													biological_process											owl:Class	
GO:0055095	biolink:NamedThing	lipoprotein particle mediated signaling	A series of molecular signals mediated by the detection of a lipoprotein particle.	got7fsn_ti	lipoprotein mediated signalling|lipoprotein particle-mediated signaling|lipoprotein particle mediated signal transduction													biological_process											owl:Class	
GO:0045181	biolink:NamedThing	glutamate synthase activity, NAD(P)H as acceptor	Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+.	got7fsn_ti	glutamate synthase activity, NADH or NADPH as acceptor													molecular_function											owl:Class	
GO:0015930	biolink:NamedThing	glutamate synthase activity	Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.	got7fsn_ti														molecular_function											owl:Class	
GO:0140297	biolink:NamedThing	DNA-binding transcription factor binding	Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.	got7fsn_ti	repressing transcription factor binding|transcription activator binding|activating transcription factor binding	https://github.com/geneontology/go-ontology/issues/19354					pg	2018-11-28T12:48:20Z			GO:0001107|GO:0033613|GO:0070491			molecular_function											owl:Class	
GO:0048069	biolink:NamedThing	eye pigmentation	Establishment of a pattern of pigment in the eye of an organism.	got7fsn_ti												Wikipedia:Eye_color		biological_process											owl:Class	
GO:0102225	biolink:NamedThing	4,4'-diaponeurosporene desaturase activity	Catalysis of the reaction: 4,4'-diaponeurosporene + FAD + H+ <=> 4,4'-diapolycopene + FADH2.	got7fsn_ti												MetaCyc:RXN-12258|RHEA:31407		molecular_function											owl:Class	
GO:0034278	biolink:NamedThing	stemar-13-ene synthase activity	Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate.	got7fsn_ti	9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming) activity											EC:4.2.3.33|KEGG_REACTION:R09115|RHEA:25552|MetaCyc:RXN-4882		molecular_function											owl:Class	
GO:0000500	biolink:NamedThing	RNA polymerase I upstream activating factor complex	A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p.	got7fsn_ti	UAF|RNA polymerase I upstream activation factor complex													cellular_component											owl:Class	
GO:0000120	biolink:NamedThing	RNA polymerase I transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I.	got7fsn_ti	RNA polymerase I transcription factor complex													cellular_component											owl:Class	
GO:0033916	biolink:NamedThing	beta-agarase activity	Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.	got7fsn_ti	agarose 4-glycanohydrolase activity|AgaB|AgaA|agarose 3-glycanohydrolase activity|agarase activity											EC:3.2.1.81		molecular_function											owl:Class	
GO:0032100	biolink:NamedThing	positive regulation of appetite	Any process that increases appetite.	got7fsn_ti	up regulation of appetite|activation of appetite|stimulation of appetite|up-regulation of appetite|positive regulation of hunger|appetite stimulation|upregulation of appetite													biological_process											owl:Class	
GO:0032097	biolink:NamedThing	positive regulation of response to food	Any process that activates, maintains, or increases the rate of a response to a food stimulus.	got7fsn_ti	upregulation of response to food|up-regulation of response to food|stimulation of response to food|up regulation of response to food|activation of response to food													biological_process											owl:Class	
GO:0006575	biolink:NamedThing	cellular modified amino acid metabolic process	The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.	got7fsn_ti	cellular modified amino acid metabolism|cellular amino acid derivative metabolism|modified amino acid metabolism|modified amino acid metabolic process|amino acid derivative metabolic process|cellular amino acid derivative metabolic process													biological_process											owl:Class	
GO:0007020	biolink:NamedThing	microtubule nucleation	The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).	got7fsn_ti												Wikipedia:Microtubule_nucleation		biological_process											owl:Class	
GO:0019328	biolink:NamedThing	anaerobic gallate catabolic process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen.	got7fsn_ti	anaerobic gallate breakdown|gallate fermentation|anaerobic gallic acid catabolism|anaerobic gallic acid catabolic process|anaerobic gallate catabolism|anaerobic gallate degradation											MetaCyc:P3-PWY		biological_process											owl:Class	
GO:0019396	biolink:NamedThing	gallate catabolic process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).	got7fsn_ti	gallate degradation|gallate metabolism|gallate catabolism|gallate metabolic process|gallic acid catabolic process|gallic acid metabolic process|gallic acid metabolism|gallic acid catabolism|gallate breakdown	https://github.com/geneontology/go-ontology/issues/20974									GO:0018918	UM-BBD_pathwayID:gal		biological_process											owl:Class	
GO:0055118	biolink:NamedThing	negative regulation of cardiac muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0045988	biolink:NamedThing	negative regulation of striated muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.	got7fsn_ti	down regulation of striated muscle contraction|inhibition of striated muscle contraction|downregulation of striated muscle contraction|down-regulation of striated muscle contraction													biological_process											owl:Class	
GO:0019420	biolink:NamedThing	dissimilatory sulfate reduction	The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.	got7fsn_ti	dissimilatory sulphate reduction											MetaCyc:DISSULFRED-PWY		biological_process											owl:Class	
GO:0043255	biolink:NamedThing	regulation of carbohydrate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.	got7fsn_ti	regulation of carbohydrate biosynthesis|regulation of carbohydrate synthesis|regulation of carbohydrate anabolism|regulation of carbohydrate formation													biological_process											owl:Class	
GO:0009889	biolink:NamedThing	regulation of biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.	got7fsn_ti	regulation of anabolism|regulation of biosynthesis|regulation of synthesis|regulation of formation													biological_process											owl:Class	
GO:0102498	biolink:NamedThing	maltose glucosidase activity	Catalysis of the reaction: H2O + maltose = 2 glucose.	got7fsn_ti												MetaCyc:RXN-15910		molecular_function											owl:Class	
GO:0102094	biolink:NamedThing	S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + a demethylmenaquinol <=> S-adenosyl-L-homocysteine  + H+ + a menaquinol.	got7fsn_ti												RHEA:26466|EC:2.1.1.163|MetaCyc:RXN-11046		molecular_function											owl:Class	
GO:1901571	biolink:NamedThing	fatty acid derivative transport	The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							pr	2012-11-04T17:13:49Z						biological_process											owl:Class	
GO:0021635	biolink:NamedThing	trigeminal nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	got7fsn_ti	CN V maturation													biological_process											owl:Class	
GO:1904363	biolink:NamedThing	negative regulation of calcitonin secretion	Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion.	got7fsn_ti	inhibition of calcitonin secretion|down-regulation of calcitonin secretion|down regulation of calcitonin secretion|downregulation of calcitonin secretion						sl	2015-06-15T17:54:58Z						biological_process											owl:Class	
GO:0046722	biolink:NamedThing	lactic acid secretion	The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue.	got7fsn_ti	lactate secretion													biological_process											owl:Class	
GO:0035879	biolink:NamedThing	plasma membrane lactate transport	The directed movement of lactate across a plasma membrane.	got7fsn_ti	lactate plasma membrane transport						bf	2011-05-31T02:54:32Z						biological_process											owl:Class	
GO:0043884	biolink:NamedThing	CO-methylating acetyl-CoA synthase activity	Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA.	got7fsn_ti	ACS|CO-methylating acetyl-coenzyme A synthase activity|acetyl-CoA:corrinoid protein O-acetyltransferase activity|acetyl-CoA synthase activity											MetaCyc:ACETYLSYNCLTH-RXN|EC:2.3.1.169|RHEA:45212		molecular_function											owl:Class	
GO:0030196	biolink:NamedThing	cyanide hydratase activity	Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide.	got7fsn_ti	formamide dehydratase activity|formamide hydro-lyase activity|formamide hydro-lyase (cyanide-forming)											EC:4.2.1.66|RHEA:21720|MetaCyc:CYANIDE-HYDRATASE-RXN|KEGG_REACTION:R01408		molecular_function											owl:Class	
GO:0047560	biolink:NamedThing	3-dehydrosphinganine reductase activity	Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH.	got7fsn_ti	D-3-dehydrosphinganine reductase activity|D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase activity|3-oxosphinganine:NADPH oxidoreductase activity|D-3-oxosphinganine reductase activity|3-oxosphinganine reductase activity|DSR activity|KTS reductase activity|3-ketosphinganine reductase activity|D-3-oxosphinganine:B-NADPH oxidoreductase activity											RHEA:22640|EC:1.1.1.102|MetaCyc:3-DEHYDROSPHINGANINE-REDUCTASE-RXN|KEGG_REACTION:R02978|Reactome:R-HSA-428123		molecular_function											owl:Class	
GO:0070670	biolink:NamedThing	response to interleukin-4	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.	got7fsn_ti	response to IL-4						mah	2009-05-29T10:01:46Z						biological_process											owl:Class	
GO:0004721	biolink:NamedThing	phosphoprotein phosphatase activity	Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.	got7fsn_ti	protein phosphatase-2B activity|protein phosphatase-2C activity|protein phosphatase-2A activity|protein phosphatase activity|protein phosphatase-1 activity|phosphoprotein phosphohydrolase activity											Reactome:R-HSA-170161|Reactome:R-HSA-174110|Reactome:R-HSA-174124|Reactome:R-HSA-69199|Reactome:R-HSA-170153|MetaCyc:3.1.3.16-RXN|Reactome:R-HSA-1363274|Reactome:R-HSA-2529015|Reactome:R-HSA-170158|Reactome:R-HSA-1363276|Reactome:R-HSA-112383|Reactome:R-HSA-113503|Reactome:R-HSA-9636684|Reactome:R-HSA-178178|Reactome:R-HSA-167072		molecular_function											owl:Class	
GO:0030668	biolink:NamedThing	merozoite dense granule membrane	The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites.	got7fsn_ti														cellular_component											owl:Class	
GO:0071614	biolink:NamedThing	linoleic acid epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.	got7fsn_ti	linoleic acid monooxygenase activity						mah	2010-02-05T06:05:22Z						molecular_function											owl:Class	
GO:0000324	biolink:NamedThing	fungal-type vacuole	A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.	got7fsn_ti	vacuole, cell cycle-correlated morphology													cellular_component											owl:Class	
GO:0000322	biolink:NamedThing	storage vacuole	A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules.	got7fsn_ti														cellular_component											owl:Class	
GO:0034678	biolink:NamedThing	integrin alpha8-beta1 complex	An integrin complex that comprises one alpha8 subunit and one beta1 subunit.	got7fsn_ti	alpha8-beta1 integrin complex|ITGA8-ITGB1 complex													cellular_component											owl:Class	
GO:0016643	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	got7fsn_ti	oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulphur protein as acceptor											EC:1.4.7.-		molecular_function											owl:Class	
GO:0051092	biolink:NamedThing	positive regulation of NF-kappaB transcription factor activity	Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.	got7fsn_ti	activation of NF-kappaB transcription factor|activation of NF-kappaB|NF-kappaB activation													biological_process											owl:Class	
GO:0051091	biolink:NamedThing	positive regulation of DNA-binding transcription factor activity	Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	got7fsn_ti	activation of transcription factor activity|positive regulation of DNA binding transcription factor activity|upregulation of transcription factor activity|positive regulation of transcription factor activity|up regulation of transcription factor activity|stimulation of transcription factor activity|up-regulation of transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of thyroid hormone receptor activity						rph	2015-04-22T12:22:16Z			GO:1904169			biological_process											owl:Class	
GO:0090292	biolink:NamedThing	nuclear matrix anchoring at nuclear membrane	The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane.	got7fsn_ti	nucleoskeleton anchoring at nuclear membrane						tb	2010-02-22T03:05:13Z						biological_process											owl:Class	
GO:0043578	biolink:NamedThing	nuclear matrix organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane.	got7fsn_ti	nuclear matrix organisation|nuclear matrix organization and biogenesis|nucleoskeleton organization													biological_process											owl:Class	
GO:0106320	biolink:NamedThing	(R)-limonene 1,2-monooxygenase NADPH activity	Catalysis of the reaction: (4R)-limonene + NADPH + H+ + O2 = NADP+ + H2O + (4R)-limonene-1,2-epoxide.	got7fsn_ti							hjd	2020-09-23T15:20:57Z				EC:1.14.13.107|RHEA:26097		molecular_function											owl:Class	
GO:0018635	biolink:NamedThing	(R)-limonene 1,2-monooxygenase activity	Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide.	got7fsn_ti	(+)-limonene 1,2-monooxygenase activity|(R)-limonene,NAD(P)H:oxygen oxidoreductase activity|(+)-limonene,NAD(P)H:oxygen oxidoreductase activity											EC:1.14.13.107|MetaCyc:RXN-9407|UM-BBD_reactionID:r0733|KEGG_REACTION:R09393|KEGG_REACTION:R06398		molecular_function											owl:Class	
GO:0071129	biolink:NamedThing	alphaV-beta3 integrin-LPP3 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3.	got7fsn_ti	ITGAV-ITGB3-PPAP2B complex						mah	2009-11-13T02:25:17Z						cellular_component											owl:Class	
GO:0032208	biolink:NamedThing	negative regulation of telomere maintenance via recombination	Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.	got7fsn_ti	downregulation of telomere maintenance via recombination|inhibition of telomere maintenance via recombination|down regulation of telomere maintenance via recombination|down-regulation of telomere maintenance via recombination													biological_process											owl:Class	
GO:0048239	biolink:NamedThing	negative regulation of DNA recombination at telomere	Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.	got7fsn_ti	down regulation of telomeric recombination at telomere|negative regulation of telomeric recombination at telomere|down-regulation of telomeric recombination at telomere|suppression of telomeric recombination at telomere|inhibition of telomeric recombination at telomere|downregulation of telomeric recombination at telomere													biological_process											owl:Class	
GO:0006928	biolink:NamedThing	movement of cell or subcellular component	The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.	got7fsn_ti	cellular component movement|cellular component motion|cell movement				Note that in GO cellular components include whole cells (cell is_a cellular component).									biological_process											owl:Class	
GO:0036169	biolink:NamedThing	3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity	Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2.	got7fsn_ti							bf	2012-03-27T04:47:47Z				Reactome:R-HSA-2162195		molecular_function											owl:Class	
GO:0010223	biolink:NamedThing	secondary shoot formation	The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs.	got7fsn_ti	auxiliary shoot formation|axillary shoot formation|axillary shoot system formation|shoot branching													biological_process											owl:Class	
GO:0001763	biolink:NamedThing	morphogenesis of a branching structure	The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.	got7fsn_ti	branching morphogenesis													biological_process											owl:Class	
GO:0004309	biolink:NamedThing	exopolyphosphatase activity	Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate.	got7fsn_ti	exopolypase activity|metaphosphatase activity|polyphosphate phosphohydrolase activity|Gra-Pase activity|acid phosphoanhydride phosphohydrolase activity											RHEA:21528|MetaCyc:EXOPOLYPHOSPHATASE-RXN|EC:3.6.1.11		molecular_function											owl:Class	
GO:0102628	biolink:NamedThing	costunolide 3beta-hydroxylase activity	Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> 3beta-hydroxycostunolide + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15533		molecular_function											owl:Class	
GO:0000758	biolink:NamedThing	agglutination involved in conjugation with mutual genetic exchange	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism.	got7fsn_ti	agglutination involved in conjugation without cellular fusion|sexual flocculation													biological_process											owl:Class	
GO:0004477	biolink:NamedThing	methenyltetrahydrofolate cyclohydrolase activity	Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.	got7fsn_ti	5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)|citrovorum factor cyclodehydrase activity|5,10-methenyl-THF cyclohydrolase activity|formyl-methenyl-methylenetetrahydrofolate synthetase (combined)											EC:3.5.4.9|Reactome:R-HSA-6801328|RHEA:23700|Reactome:R-HSA-200661|MetaCyc:METHENYLTHFCYCLOHYDRO-RXN|Reactome:R-HSA-200740		molecular_function											owl:Class	
GO:0052154	biolink:NamedThing	modulation by symbiont of host B-cell mediated immune response	Any process in which a symbiont modulates the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction|regulation by organism of host B-cell mediated immune response										GO:0052293			biological_process											owl:Class	
GO:0052553	biolink:NamedThing	modulation by symbiont of host immune response	Any process in which a symbiont modulates the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of immune response of other organism involved in symbiotic interaction										GO:0052552			biological_process											owl:Class	
GO:0015954	biolink:NamedThing	pyrimidine ribonucleotide interconversion	The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide.	got7fsn_ti														biological_process											owl:Class	
GO:0009218	biolink:NamedThing	pyrimidine ribonucleotide metabolic process	The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine ribonucleotide metabolism													biological_process											owl:Class	
GO:0046190	biolink:NamedThing	aerobic phenol-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.	got7fsn_ti	aerobic phenol-containing compound formation|aerobic phenol-containing compound anabolism|aerobic phenol-containing compound synthesis|aerobic phenol-containing compound biosynthesis													biological_process											owl:Class	
GO:0046189	biolink:NamedThing	phenol-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.	got7fsn_ti	phenol-containing compound formation|phenol-containing compound biosynthesis|phenol-containing compound anabolism|phenol-containing compound synthesis													biological_process											owl:Class	
GO:0060304	biolink:NamedThing	regulation of phosphatidylinositol dephosphorylation	Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.	got7fsn_ti	regulation of phosphoinositide dephosphorylation													biological_process											owl:Class	
GO:0060255	biolink:NamedThing	regulation of macromolecule metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti														biological_process											owl:Class	
GO:0019777	biolink:NamedThing	Atg12 transferase activity	Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.	got7fsn_ti	Atg12 conjugating enzyme activity|APG12 conjugating enzyme activity|APG12 ligase activity|Atg12 ligase activity											Reactome:R-HSA-5681999		molecular_function											owl:Class	
GO:0097451	biolink:NamedThing	glial limiting end-foot	Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans.	got7fsn_ti	glial limiting endfoot						pr	2012-12-17T13:36:34Z				NIF_Subcellular:sao181458425		cellular_component											owl:Class	
GO:0097450	biolink:NamedThing	astrocyte end-foot	Terminal process of astrocyte abutting non-neuronal surfaces in the brain.	got7fsn_ti	astrocyte endfoot						pr	2012-12-17T13:33:55Z				NIF_Subcellular:sao388182739		cellular_component											owl:Class	
GO:0098777	biolink:NamedThing	protein secretion by the type VIII secretion system	Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits.	got7fsn_ti	T8SS				This term is defined so as to leave open the possibility that things other than curli subunits are secreted via same secretory system as that used by curli subunits.									biological_process											owl:Class	
GO:0102681	biolink:NamedThing	isoamylase (maltodextrin-releasing) activity	Catalysis of the reaction: n H2O + a glycogen <=> n a maltodextrin.	got7fsn_ti												MetaCyc:RXN-4301		molecular_function											owl:Class	
GO:0045469	biolink:NamedThing	negative regulation of R8 cell spacing in compound eye	Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.	got7fsn_ti	inhibition of R8 spacing|downregulation of R8 spacing|down regulation of R8 spacing|down-regulation of R8 spacing													biological_process											owl:Class	
GO:0045468	biolink:NamedThing	regulation of R8 cell spacing in compound eye	Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc.	got7fsn_ti	R8 cell spacing in compound eye|regulation of R8 spacing													biological_process											owl:Class	
GO:0060658	biolink:NamedThing	nipple morphogenesis	The process in which the nipple is generated and organized.	got7fsn_ti							dph	2009-05-29T10:45:44Z						biological_process											owl:Class	
GO:0090605	biolink:NamedThing	submerged biofilm formation	A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	got7fsn_ti	solid substrate biofilm formation						tb	2014-09-16T14:44:46Z						biological_process											owl:Class	
GO:1990349	biolink:NamedThing	gap junction-mediated intercellular transport	The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells.	got7fsn_ti							hjd	2014-03-25T18:05:44Z						biological_process											owl:Class	
GO:0010496	biolink:NamedThing	intercellular transport	The movement of substances between cells.	got7fsn_ti	single-organism intercellular transport|single organism intercellular transport						jl	2013-12-19T13:24:56Z			GO:1902585			biological_process											owl:Class	
GO:0002771	biolink:NamedThing	inhibitory killer cell immunoglobulin-like receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response.	got7fsn_ti	inhibitory killer cell immunoglobulin-like receptor signalling pathway|KIR signaling pathway|killer cell inhibitory receptor signaling pathway													biological_process											owl:Class	
GO:0051361	biolink:NamedThing	peptide cross-linking via L-lysine 5-imidazolinone glycine	The formation of a fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	got7fsn_ti	biosynthesis of protein-protein cross-link via L-lysine 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via L-lysine 5-imidazolinone glycine				See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.							RESID:AA0381		biological_process											owl:Class	
GO:0060652	biolink:NamedThing	mammary gland cord morphogenesis	The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.	got7fsn_ti	mammary gland sprout morphogenesis						dph	2009-05-29T09:06:56Z						biological_process											owl:Class	
GO:0097324	biolink:NamedThing	melanocyte migration	The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.	got7fsn_ti							pr	2012-06-08T10:08:18Z						biological_process											owl:Class	
GO:0140587	biolink:NamedThing	chromatin loop anchoring activity	Bridging together two DNA loop anchors together, maintaining a chromatin loop.	got7fsn_ti	DNA loop binding|chromosomal loop binding	https://github.com/geneontology/go-ontology/issues/20204					pg	2021-02-04T14:53:13Z						molecular_function											owl:Class	
GO:0090148	biolink:NamedThing	membrane fission	A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes.	got7fsn_ti	membrane scission						tb	2009-12-08T03:06:36Z						biological_process											owl:Class	
GO:0090106	biolink:NamedThing	pancreatic E cell fate commitment	The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell.	got7fsn_ti							tb	2009-11-18T11:51:41Z						biological_process											owl:Class	
GO:0051077	biolink:NamedThing	secondary cell septum	Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum.	got7fsn_ti	secondary septum													cellular_component											owl:Class	
GO:0000935	biolink:NamedThing	division septum	A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.	got7fsn_ti	septum surface|cell septum surface|complete septum|divison septum	https://github.com/geneontology/go-ontology/issues/19434									GO:0043187			cellular_component											owl:Class	
GO:0090377	biolink:NamedThing	seed trichome initiation	The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis.	got7fsn_ti	seed trichome fate commitment				These processes continue up to 3 days post-anthesis (DPA) in Gossypium spp.		tb	2010-09-15T02:13:59Z						biological_process											owl:Class	
GO:0019129	biolink:NamedThing	peptidyl-leucine racemization	The racemization of peptidyl-leucine.	got7fsn_ti											GO:0018093|GO:0018375	RESID:AA0197		biological_process											owl:Class	
GO:0032394	biolink:NamedThing	MHC class Ib receptor activity	Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.	got7fsn_ti	T cell receptor activity|alpha-beta T cell receptor activity|gamma-delta T cell receptor activity				Note that this term is intended for annotation of gene products that act as receptors for MHC class Ib protein complexes, not for components of the MHC class Ib protein complexes themselves.									molecular_function											owl:Class	
GO:1990627	biolink:NamedThing	mitochondrial inner membrane fusion	The membrane organization process that joins two mitochondrial inner membranes to form a single membrane.	got7fsn_ti	mitochondrion inner membrane fusion						vw	2015-02-02T11:37:56Z						biological_process											owl:Class	
GO:0007007	biolink:NamedThing	inner mitochondrial membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane.	got7fsn_ti	mitochondrial inner membrane organization|inner mitochondrial membrane organization and biogenesis|inner mitochondrial membrane organisation				See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.									biological_process											owl:Class	
GO:0005791	biolink:NamedThing	rough endoplasmic reticulum	The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.	got7fsn_ti	rough ER|RER											NIF_Subcellular:sao1881364067|Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum		cellular_component											owl:Class	
GO:0005783	biolink:NamedThing	endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).	got7fsn_ti	ER											Wikipedia:Endoplasmic_reticulum|NIF_Subcellular:sao1036339110		cellular_component											owl:Class	
GO:0008273	biolink:NamedThing	calcium, potassium:sodium antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in).	got7fsn_ti	potassium-dependent sodium/calcium exchanger											Reactome:R-HSA-2514891|Reactome:R-HSA-5626316|Reactome:R-HSA-5626270|Reactome:R-HSA-5626356|Reactome:R-HSA-5625841|Reactome:R-HSA-425678		molecular_function											owl:Class	
GO:0022821	biolink:NamedThing	potassium ion antiporter activity	Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	got7fsn_ti														molecular_function											owl:Class	
GO:1990459	biolink:NamedThing	transferrin receptor binding	Binding to a transferrin receptor.	got7fsn_ti							tb	2014-08-18T20:14:24Z						molecular_function											owl:Class	
GO:0045994	biolink:NamedThing	positive regulation of translational initiation by iron	Any process involving iron that activates or increases the rate of translational initiation.	got7fsn_ti	stimulation of translational initiation by iron|upregulation of translational initiation by iron|activation of translational initiation by iron|up regulation of translational initiation by iron|up-regulation of translational initiation by iron													biological_process											owl:Class	
GO:0004749	biolink:NamedThing	ribose phosphate diphosphokinase activity	Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).	got7fsn_ti	ribose-phosphate pyrophosphokinase activity|ribophosphate pyrophosphokinase activity|ribose-5-phosphate pyrophosphokinase activity|pyrophosphoribosylphosphate synthetase activity|phosphoribosyl-diphosphate synthetase activity|PP-ribose P synthetase activity|ribose-phosphate diphosphokinase activity|phosphoribosyl diphosphate synthetase activity|PRPP synthetase activity|phosphoribosylpyrophosphate synthase activity|phosphoribosylpyrophosphate synthetase activity|ATP:D-ribose-5-phosphate diphosphotransferase activity|phosphoribosyl pyrophosphate synthetase activity|5-phosphoribose pyrophosphorylase activity|5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity|PPRibP synthetase activity|5-phosphoribosyl-1-pyrophosphate synthetase activity											RHEA:15609|EC:2.7.6.1|Reactome:R-HSA-73580|KEGG_REACTION:R01049|MetaCyc:PRPPSYN-RXN|MetaCyc:PWY0-662|Reactome:R-HSA-111215		molecular_function											owl:Class	
GO:0016778	biolink:NamedThing	diphosphotransferase activity	Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).	got7fsn_ti												EC:2.7.6.-		molecular_function											owl:Class	
GO:0032933	biolink:NamedThing	SREBP signaling pathway	A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.	got7fsn_ti	sterol depletion response, SREBP target gene transcriptional activation|stimulation of sterol regulatory element binding protein target gene transcription|upregulation of sterol regulatory element binding protein target gene transcription|positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response|ER-nuclear sterol response pathway|positive regulation of sterol regulatory element binding protein target gene transcription|up-regulation of sterol regulatory element binding protein target gene transcription|SREBP target gene transcriptional activation|sterol regulatory element binding protein target gene transcriptional activation|positive regulation of transcription via sterol regulatory element binding|SREBP signalling|up regulation of sterol regulatory element binding protein target gene transcription|endoplasmic reticulum to nucleus sterol response pathway|SREBP-mediated signalling pathway|ER to nucleus sterol response pathway|endoplasmic reticulum-nuclear sterol response pathway|positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway|sterol response element binding protein signaling pathway|activation of sterol regulatory element binding protein target gene transcription|SREBP-mediated signaling pathway										GO:0035104|GO:0030967|GO:0006994			biological_process											owl:Class	
GO:0006984	biolink:NamedThing	ER-nucleus signaling pathway	Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation.	got7fsn_ti	ER-nuclear signaling pathway|endoplasmic reticulum to nucleus signaling pathway|ER to nucleus signalling pathway|endoplasmic reticulum-nuclear signaling pathway|ER to nucleus signaling pathway|ER-nuclear signalling pathway													biological_process											owl:Class	
GO:0098960	biolink:NamedThing	postsynaptic neurotransmitter receptor activity	Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission.	got7fsn_ti	neurotransmitter receptor activity involved in chemical synaptic transmission													molecular_function											owl:Class	
GO:0035623	biolink:NamedThing	renal glucose absorption	A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	got7fsn_ti	glucose reabsorption|nephron glucose absorption						bf	2010-12-08T04:14:23Z						biological_process											owl:Class	
GO:1904659	biolink:NamedThing	glucose transmembrane transport	The process in which glucose is transported across a membrane.	got7fsn_ti	glucose transport						vw	2015-09-04T17:20:16Z			GO:0015758			biological_process											owl:Class	
GO:0022610	biolink:NamedThing	biological adhesion	The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.	got7fsn_ti														biological_process											owl:Class	
GO:0047518	biolink:NamedThing	1-methyladenosine nucleosidase activity	Catalysis of the reaction: 1-methyladenosine + H(2)O = 1-methyladenine + ribofuranose.	got7fsn_ti	1-methyladenosine ribohydrolase activity|1-methyladenosine hydrolase activity											MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN|KEGG_REACTION:R03885|RHEA:12865|EC:3.2.2.13		molecular_function											owl:Class	
GO:0039023	biolink:NamedThing	pronephric duct morphogenesis	The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.	got7fsn_ti							bf	2010-07-02T10:18:09Z						biological_process											owl:Class	
GO:0072178	biolink:NamedThing	nephric duct morphogenesis	The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney.	got7fsn_ti							mah	2010-02-26T02:35:29Z						biological_process											owl:Class	
GO:0007174	biolink:NamedThing	epidermal growth factor catabolic process	The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor.	got7fsn_ti	EGF catabolism|epidermal growth factor breakdown|EGF breakdown|epidermal growth factor ligand processing|epidermal growth factor catabolism|EGF receptor ligand processing|receptor-mediated EGF processing|intracellular EGF processing				This term describes the breakdown of epidermal growth factor within the cell, following internalization. For proteolysis events that result in the maturation of an epidermal growth factor receptor ligand, see 'epidermal growth factor receptor ligand maturation ; GO:'.									biological_process											owl:Class	
GO:0042059	biolink:NamedThing	negative regulation of epidermal growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.	got7fsn_ti	inhibition of epidermal growth factor receptor signaling pathway|down-regulation of epidermal growth factor receptor signaling pathway|down regulation of epidermal growth factor receptor signaling pathway|negative regulation of EGF receptor signaling pathway|downregulation of epidermal growth factor receptor signaling pathway|negative regulation of EGFR signaling pathway|negative regulation of EGF receptor signalling pathway													biological_process											owl:Class	
GO:0016163	biolink:NamedThing	nitrogenase activity	Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.	got7fsn_ti	reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) activity|vanadium-iron nitrogenase activity|iron-iron nitrogenase activity|molybdenum-iron nitrogenase activity											UM-BBD_enzymeID:e0395|RHEA:21448|MetaCyc:NITROGENASE-RXN|EC:1.18.6.1		molecular_function											owl:Class	
GO:0016732	biolink:NamedThing	oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen.	got7fsn_ti												EC:1.18.6.-		molecular_function											owl:Class	
GO:0009747	biolink:NamedThing	hexokinase-dependent signaling	A series of molecular signals mediated by hexose and dependent on the detection of hexokinase.	got7fsn_ti	hexokinase-dependent signalling													biological_process											owl:Class	
GO:0050189	biolink:NamedThing	phosphoenolpyruvate phosphatase activity	Catalysis of the reaction: H(2)O + phosphoenolpyruvate = phosphate + pyruvate.	got7fsn_ti	PEP phosphatase activity|phosphoenolpyruvate phosphohydrolase activity											EC:3.1.3.60|KEGG_REACTION:R00208|MetaCyc:PHOSPHOENOLPYRUVATE-PHOSPHATASE-RXN|RHEA:19997		molecular_function											owl:Class	
GO:0018344	biolink:NamedThing	protein geranylgeranylation	The covalent attachment of a geranylgeranyl group to a protein.	got7fsn_ti	C-terminal protein geranylgeranylation|protein amino acid geranylgeranylation										GO:0018348			biological_process											owl:Class	
GO:0018342	biolink:NamedThing	protein prenylation	The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.	got7fsn_ti	protein amino acid prenylation|C-terminal protein prenylation										GO:0018346			biological_process											owl:Class	
GO:0047665	biolink:NamedThing	aminolevulinate transaminase activity	Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine.	got7fsn_ti	aminolevulinate aminotransferase activity|dioxovalerate transaminase activity|gamma,delta-dioxovaleric acid transaminase activity|5-aminolevulinate:pyruvate aminotransferase activity|alanine:4,5-dioxovalerate aminotransferase activity|gamma,delta-dioxovalerate aminotransferase activity|L-alanine:4,5-dioxovaleric acid transaminase activity|4,5-dioxovalerate aminotransferase activity|L-alanine-4,5-dioxovalerate aminotransferase activity|4,5-dioxovaleric transaminase activity|4,5-dioxovaleric acid transaminase activity|DOVA transaminase activity|5-aminolevulinic acid transaminase activity|alanine-gamma,delta-dioxovalerate aminotransferase activity|4,5-dioxovaleric acid aminotransferase activity|alanine-dioxovalerate aminotransferase activity|aminolevulinic acid transaminase activity|L-alanine:dioxovalerate transaminase activity											KEGG_REACTION:R02271|MetaCyc:AMINOLEVULINATE-AMINOTRANSFERASE-RXN|EC:2.6.1.43|RHEA:12480		molecular_function											owl:Class	
GO:0043949	biolink:NamedThing	regulation of cAMP-mediated signaling	Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.	got7fsn_ti	regulation of cAMP-mediated signalling													biological_process											owl:Class	
GO:0070208	biolink:NamedThing	protein heterotrimerization	The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.	got7fsn_ti	protein heterotrimer formation|protein heterotrimer biosynthetic process|protein heterotrimer assembly|protein heterotrimer biosynthesis													biological_process											owl:Class	
GO:0070206	biolink:NamedThing	protein trimerization	The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.	got7fsn_ti	protein trimer assembly|protein trimer formation|protein trimer biosynthesis|protein trimer biosynthetic process													biological_process											owl:Class	
GO:0009951	biolink:NamedThing	polarity specification of dorsal/ventral axis	Any process resulting in the establishment of polarity along the dorsal/ventral axis.	got7fsn_ti	polarity specification of dorsoventral axis|polarity specification of dorsal-ventral axis													biological_process											owl:Class	
GO:0065001	biolink:NamedThing	specification of axis polarity	The pattern specification process in which the polarity of a body or organ axis is established and maintained.	got7fsn_ti														biological_process											owl:Class	
GO:0060707	biolink:NamedThing	trophoblast giant cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.	got7fsn_ti							dph	2009-06-09T10:32:12Z						biological_process											owl:Class	
GO:0060706	biolink:NamedThing	cell differentiation involved in embryonic placenta development	The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.	got7fsn_ti							dph	2009-06-09T10:26:42Z						biological_process											owl:Class	
BFO:0000015	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0055073	biolink:NamedThing	cadmium ion homeostasis	Any process involved in the maintenance of an internal steady state of cadmium ions within an organism or cell.	got7fsn_ti	cadmium homeostasis													biological_process											owl:Class	
GO:0072507	biolink:NamedThing	divalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell.	got7fsn_ti					Note that this term was split from 'di-, tri-valent inorganic cation homeostasis ; GO:0055066' (sibling term 'trivalent inorganic cation homeostasis' ; GO:0072508').		mah	2010-12-16T03:22:48Z						biological_process											owl:Class	
GO:0003329	biolink:NamedThing	pancreatic PP cell fate commitment	The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.	got7fsn_ti							dph	2009-11-02T08:35:13Z						biological_process											owl:Class	
GO:0004989	biolink:NamedThing	octopamine receptor activity	Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist.	got7fsn_ti														molecular_function											owl:Class	
GO:0008227	biolink:NamedThing	G protein-coupled amine receptor activity	Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	biogenic amine receptor|amine receptor activity, G-protein coupled|G-protein coupled amine receptor activity													molecular_function											owl:Class	
GO:0048675	biolink:NamedThing	axon extension	Long distance growth of a single axon process involved in cellular development.	got7fsn_ti	axon extension involved in development										GO:0048676			biological_process											owl:Class	
GO:0060539	biolink:NamedThing	diaphragm development	The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.	got7fsn_ti							dph	2009-04-10T08:44:56Z						biological_process											owl:Class	
GO:0060538	biolink:NamedThing	skeletal muscle organ development	The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.	got7fsn_ti							dph	2009-04-10T08:25:12Z						biological_process											owl:Class	
GO:0044563	biolink:NamedThing	envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism.	got7fsn_ti	voltage-dependence of activation shift (to the left)						jl	2012-04-05T04:06:29Z						biological_process											owl:Class	
GO:0097314	biolink:NamedThing	apoptosome assembly	The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process.	got7fsn_ti	apoptosome formation						pr	2012-05-28T03:39:49Z						biological_process											owl:Class	
GO:0008685	biolink:NamedThing	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP.	got7fsn_ti	2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming)|MECDP-synthase activity|2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)|MECP synthase activity											MetaCyc:RXN0-302|EC:4.6.1.12|RHEA:23864|KEGG_REACTION:R05637		molecular_function											owl:Class	
GO:0044013	biolink:NamedThing	H2B histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.	got7fsn_ti	H2B histone lysine N-acetyltransferase activity													molecular_function											owl:Class	
GO:0035721	biolink:NamedThing	intraciliary retrograde transport	The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.	got7fsn_ti	intraflagellar retrograde transport				Note that we deem cilium and microtubule-based flagellum to be equivalent.		bf	2011-03-07T11:25:32Z						biological_process											owl:Class	
GO:0060026	biolink:NamedThing	convergent extension	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.	got7fsn_ti												Wikipedia:Convergent_extension		biological_process											owl:Class	
GO:0032135	biolink:NamedThing	DNA insertion or deletion binding	Binding to a double-stranded DNA region containing an insertion or a deletion.	got7fsn_ti	insertion binding|DNA insertion binding													molecular_function											owl:Class	
GO:0008296	biolink:NamedThing	3'-5'-exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule.	got7fsn_ti	3'-5' exodeoxyribonuclease activity											Reactome:R-HSA-9023943		molecular_function											owl:Class	
GO:0033711	biolink:NamedThing	4-phosphoerythronate dehydrogenase activity	Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH.	got7fsn_ti	erythronate-4-phosphate dehydrogenase activity|PdxB 4PE dehydrogenase activity|4PE dehydrogenase activity|4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity|PdxB|4-O-phosphoerythronate dehydrogenase activity											RHEA:18829|EC:1.1.1.290|KEGG_REACTION:R04210|MetaCyc:ERYTHRON4PDEHYDROG-RXN		molecular_function											owl:Class	
GO:0045617	biolink:NamedThing	negative regulation of keratinocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.	got7fsn_ti	down-regulation of keratinocyte differentiation|down regulation of keratinocyte differentiation|inhibition of keratinocyte differentiation|downregulation of keratinocyte differentiation													biological_process											owl:Class	
GO:0045616	biolink:NamedThing	regulation of keratinocyte differentiation	Any process that modulates the frequency, rate or extent of keratinocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0090553	biolink:NamedThing	unicellular trichome tip	A cell projection part that is the apical most portion of a unicellular trichome apex.	got7fsn_ti							tb	2013-04-25T11:56:56Z						cellular_component											owl:Class	
GO:0007179	biolink:NamedThing	transforming growth factor beta receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	TGFbeta receptor signalling pathway|TGF-beta receptor signalling pathway|TGFbeta receptor signaling pathway|TGF-beta receptor signaling pathway|transforming growth factor beta receptor signalling pathway													biological_process											owl:Class	
GO:0007178	biolink:NamedThing	transmembrane receptor protein serine/threonine kinase signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	transmembrane receptor protein serine/threonine kinase signalling pathway													biological_process											owl:Class	
GO:0033165	biolink:NamedThing	interphotoreceptor matrix	A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.	got7fsn_ti														cellular_component											owl:Class	
GO:0044657	biolink:NamedThing	pore formation in membrane of other organism during symbiotic interaction	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism, occurring as part of a symbiotic interaction.	got7fsn_ti							jl	2012-08-01T13:12:10Z						biological_process											owl:Class	
GO:0035915	biolink:NamedThing	pore formation in membrane of other organism	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism.	got7fsn_ti	pore complex assembly in other organism|pore biosynthesis in other organism|pore formation in other organism|pore-forming toxin activity|pore complex biogenesis in other organism						bf	2011-07-01T11:45:01Z						biological_process											owl:Class	
GO:0007418	biolink:NamedThing	ventral midline development	The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.	got7fsn_ti														biological_process											owl:Class	
GO:0061395	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.	got7fsn_ti							dph	2011-12-14T08:53:20Z						biological_process											owl:Class	
GO:0034607	biolink:NamedThing	turning behavior involved in mating	The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.	got7fsn_ti	turning behavior during mating													biological_process											owl:Class	
GO:0060179	biolink:NamedThing	male mating behavior	The specific behavior of a male organism that is associated with reproduction.	got7fsn_ti														biological_process											owl:Class	
GO:0044315	biolink:NamedThing	protein secretion by the type VII secretion system	The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system.	got7fsn_ti							jl	2010-06-02T11:57:05Z						biological_process											owl:Class	
GO:0034394	biolink:NamedThing	protein localization to cell surface	A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.	got7fsn_ti	protein localisation at cell surface|protein localization at cell surface													biological_process											owl:Class	
GO:0043052	biolink:NamedThing	thermotaxis	The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.	got7fsn_ti	taxis in response to temperature stimulus											Wikipedia:Thermotaxis		biological_process											owl:Class	
GO:0019287	biolink:NamedThing	isopentenyl diphosphate biosynthetic process, mevalonate pathway	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.	got7fsn_ti	isopentenyl diphosphate biosynthetic process via mevalonate|isopentenyl diphosphate anabolism, mevalonate pathway|isopentenyl diphosphate formation, mevalonate pathway|acetate-mevalonate pathway|Ac-MVA pathway|isopentenyl diphosphate synthesis, mevalonate pathway													biological_process											owl:Class	
GO:0009240	biolink:NamedThing	isopentenyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.	got7fsn_ti	IPP biosynthesis|isopentenyl diphosphate anabolism|isopentenyl diphosphate synthesis|IPP biosynthetic process|isopentenyl pyrophosphate biosynthesis|isopentenyl diphosphate formation|isopentenyl diphosphate biosynthesis|isopentenyl pyrophosphate biosynthetic process													biological_process											owl:Class	
GO:0009111	biolink:NamedThing	vitamin catabolic process	The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	got7fsn_ti	vitamin degradation|vitamin breakdown|vitamin catabolism													biological_process											owl:Class	
GO:0038174	biolink:NamedThing	interleukin-17A receptor activity	Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti							bf	2012-06-12T11:01:25Z						molecular_function											owl:Class	
GO:0030368	biolink:NamedThing	interleukin-17 receptor activity	Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-17 receptor activity|IL-17R											Wikipedia:Interleukin-17_receptor		molecular_function											owl:Class	
GO:0019122	biolink:NamedThing	peptidyl-D-alanine racemization	The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine.	got7fsn_ti	alanine racemization				See also the biological process terms 'peptidyl-D-alanine racemization, direct ; GO:0019916' and 'peptidyl-D-alanine racemization via peptidyl-L-serine ; GO:0019917'.							RESID:AA0191		biological_process											owl:Class	
GO:0050670	biolink:NamedThing	regulation of lymphocyte proliferation	Any process that modulates the frequency, rate or extent of lymphocyte proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0033484	biolink:NamedThing	nitric oxide homeostasis	A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.	got7fsn_ti	NO homeostasis													biological_process											owl:Class	
GO:0033483	biolink:NamedThing	gas homeostasis	A homeostatic process involved in the maintenance of an internal steady state of a gas within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0034293	biolink:NamedThing	sexual sporulation	The formation of spores derived from the products of meiosis.	got7fsn_ti	meiotic sporulation|meiotic spore formation|sexual spore formation													biological_process											owl:Class	
GO:0043934	biolink:NamedThing	sporulation	The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	got7fsn_ti												Wikipedia:Spore		biological_process											owl:Class	
GO:0034588	biolink:NamedThing	piRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	got7fsn_ti	piRNA breakdown|piRNA degradation|Piwi-associated RNA catabolic process|piRNA catabolism													biological_process											owl:Class	
GO:0034661	biolink:NamedThing	ncRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).	got7fsn_ti	ncRNA degradation|ncRNA breakdown|ncRNA catabolism													biological_process											owl:Class	
GO:0034492	biolink:NamedThing	hydrogenosome lumen	The volume enclosed by the hydrogenosome membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0021552	biolink:NamedThing	midbrain-hindbrain boundary structural organization	The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	got7fsn_ti	MHB structural organization|isthmus structural organization|midbrain-hindbrain boundary structural organisation													biological_process											owl:Class	
GO:0007594	biolink:NamedThing	puparial adhesion	The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation.	got7fsn_ti	puparial glue													biological_process											owl:Class	
GO:0022609	biolink:NamedThing	multicellular organism adhesion to substrate	The attachment of a multicellular organism to a surface or material.	got7fsn_ti														biological_process											owl:Class	
GO:1990474	biolink:NamedThing	synaptic vesicle, readily releasable pool	A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton.	got7fsn_ti	readily releasable pool of synaptic vesicles|RRP						pr	2014-09-02T09:02:41Z						cellular_component											owl:Class	
GO:0031804	biolink:NamedThing	type 7 metabotropic glutamate receptor binding	Binding to a type 7 metabotropic glutamate receptor.	got7fsn_ti	type 7 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0060012	biolink:NamedThing	synaptic transmission, glycinergic	The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	got7fsn_ti	glycinergic synaptic transmission													biological_process											owl:Class	
GO:0018071	biolink:NamedThing	NAD(P)-cysteine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine.	got7fsn_ti														molecular_function											owl:Class	
GO:0061566	biolink:NamedThing	CMP phosphorylation	The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP.	got7fsn_ti							dph	2013-08-01T12:52:39Z						biological_process											owl:Class	
GO:0017182	biolink:NamedThing	peptidyl-diphthamide metabolic process	The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue.	got7fsn_ti	peptidyl-diphthamide metabolism													biological_process											owl:Class	
GO:0050851	biolink:NamedThing	antigen receptor-mediated signaling pathway	A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.	got7fsn_ti	antigen receptor-mediated signalling pathway													biological_process											owl:Class	
GO:0002429	biolink:NamedThing	immune response-activating cell surface receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response.	got7fsn_ti	immune response-activating cell surface receptor signalling pathway|activation of immune response by cell surface receptor signaling pathway													biological_process											owl:Class	
GO:0106101	biolink:NamedThing	ER-dependent peroxisome localization	A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum.	got7fsn_ti							hjd	2018-02-15T17:54:20Z						biological_process											owl:Class	
GO:0072662	biolink:NamedThing	protein localization to peroxisome	A process in which a protein is transported to, or maintained at, a location in a peroxisome.	got7fsn_ti	protein localisation to peroxisome						mah	2011-02-14T02:50:04Z						biological_process											owl:Class	
GO:0090120	biolink:NamedThing	lysosome to ER cholesterol transport	The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum.	got7fsn_ti	lysosome to endoplasmic reticulum cholesterol transport						tb	2009-12-07T12:22:12Z						biological_process											owl:Class	
GO:0090119	biolink:NamedThing	vesicle-mediated cholesterol transport	The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles.	got7fsn_ti							tb	2009-12-07T12:14:37Z						biological_process											owl:Class	
GO:0106175	biolink:NamedThing	phagolysosome vesicle membrane	The lipid bylayer surrounding a phagolysosome.	got7fsn_ti							hjd	2019-02-11T19:12:53Z						cellular_component											owl:Class	
GO:0007313	biolink:NamedThing	maternal specification of dorsal/ventral axis, oocyte, soma encoded	Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster.	got7fsn_ti	maternal specification of dorsoventral axis, oocyte, soma encoded|maternal determination of dorsal/ventral axis, oocyte, soma encoded|maternal specification of dorsal-ventral axis, oocyte, soma encoded										GO:0048125			biological_process											owl:Class	
GO:0009826	biolink:NamedThing	unidimensional cell growth	The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.	got7fsn_ti	cell elongation|polar cell growth|polarized cell growth|cell growth along one axis|cell growth in one dimension|cell morphogenesis by unidimensional growth				Unidimensional cell growth refers to a change in both cell size and cell shape. For cell shape changes where cell size is not affected, consider instead the term 'regulation of cell shape ; GO:0008360' and its children.									biological_process											owl:Class	
GO:0102375	biolink:NamedThing	11-oxo-beta-amyrin 30-oxidase activity	Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ <=> glycyrrhetinic acid + 3 NADP + 4 H2O.	got7fsn_ti												RHEA:35499|EC:1.14.14.115|MetaCyc:RXN-13506		molecular_function											owl:Class	
GO:0098535	biolink:NamedThing	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation.	got7fsn_ti	de novo centriole assembly|centriole amplification|deuterosome pathway|de novo centriole assembly via deuterosome|deuterosome-mediated centriole biogenesis|deuterosomal basal body biogenesis|multiciliation|multiciliogenesis				In most eukaryotic cells, 'centriole' (GO:0005814) and 'ciliary basal body' (GO:0036064) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.		dos	2013-10-22T16:03:13Z						biological_process											owl:Class	
GO:0097742	biolink:NamedThing	de novo centriole assembly	Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects.	got7fsn_ti	de novo basal body biogenesis|de novo basal body generation|multiciliogenesis|acentriolar basal body biogenesis|de novo basal body assembly|de novo basal body amplification|de novo centriole amplification|de novo ciliary basal body assembly|multiciliation						pr	2016-10-19T15:13:50Z						biological_process											owl:Class	
GO:0048366	biolink:NamedThing	leaf development	The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0048827	biolink:NamedThing	phyllome development	The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants.	got7fsn_ti														biological_process											owl:Class	
GO:0000458	biolink:NamedThing	endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0000449	biolink:NamedThing	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0006488	biolink:NamedThing	dolichol-linked oligosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P.	got7fsn_ti	N-linked glycan precursor biosynthesis|dolichol-linked oligosaccharide synthesis|dolichol-linked oligosaccharide formation|dolichol-linked oligosaccharide biosynthesis|dolichol-linked oligosaccharide anabolism|N-linked glycan precursor biosynthetic process|oligosaccharide-PP-dolichol assembly													biological_process											owl:Class	
GO:0006490	biolink:NamedThing	oligosaccharide-lipid intermediate biosynthetic process	The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation.	got7fsn_ti	oligosaccharide-lipid intermediate assembly|oligosaccharide-lipid intermediate biosynthetic process													biological_process											owl:Class	
GO:0097147	biolink:NamedThing	NOXA-BCL-2 complex	A heterodimeric protein complex consisting of NOXA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:50:14Z						cellular_component											owl:Class	
GO:0055078	biolink:NamedThing	sodium ion homeostasis	Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0055065	biolink:NamedThing	metal ion homeostasis	Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0000402	biolink:NamedThing	crossed form four-way junction DNA binding	Binding to a DNA segment containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands.	got7fsn_ti	crossed form Holliday junction binding													molecular_function											owl:Class	
GO:0000400	biolink:NamedThing	four-way junction DNA binding	Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.	got7fsn_ti	forked DNA binding|Holliday junction binding													molecular_function											owl:Class	
GO:0060756	biolink:NamedThing	foraging behavior	Behavior by which an organism locates food.	got7fsn_ti							dph	2009-06-22T02:46:25Z						biological_process											owl:Class	
GO:0016006	biolink:NamedThing	Nebenkern	A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20737												cellular_component											owl:Class	
GO:0016007	biolink:NamedThing	mitochondrial derivative	The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20737												cellular_component											owl:Class	
GO:0047141	biolink:NamedThing	glutathione-cystine transhydrogenase activity	Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine.	got7fsn_ti	GSH-cystine transhydrogenase|NADPH-dependent GSH-cystine transhydrogenase|glutathione:cystine oxidoreductase											EC:1.8.4.4|MetaCyc:1.8.4.4-RXN|RHEA:12613		molecular_function											owl:Class	
GO:0009269	biolink:NamedThing	response to desiccation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.	got7fsn_ti	desiccation tolerance													biological_process											owl:Class	
GO:0009414	biolink:NamedThing	response to water deprivation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.	got7fsn_ti	response to drought|response to thirst|response to dehydration|drought tolerance													biological_process											owl:Class	
GO:0016798	biolink:NamedThing	hydrolase activity, acting on glycosyl bonds	Catalysis of the hydrolysis of any glycosyl bond.	got7fsn_ti	glycosylase|glycosidase activity|N-glycosylase											Reactome:R-HSA-1793176|EC:3.2.-.-|Reactome:R-HSA-2065233		molecular_function											owl:Class	
GO:0060734	biolink:NamedThing	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.	got7fsn_ti	regulation of eIF2 alpha phosphorylation by ER stress|regulation of ER stress-induced eIF2 alpha phosphorylation|regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress						dph	2009-06-12T02:15:16Z						biological_process											owl:Class	
GO:0080135	biolink:NamedThing	regulation of cellular response to stress	Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti							dhl	2009-05-06T05:02:52Z						biological_process											owl:Class	
GO:0033945	biolink:NamedThing	oligoxyloglucan reducing-end-specific cellobiohydrolase activity	Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.	got7fsn_ti	oligoxyloglucan reducing end-specific cellobiohydrolase activity|oligoxyloglucan reducing-end cellobiohydrolase activity											EC:3.2.1.150|MetaCyc:3.2.1.150-RXN		molecular_function											owl:Class	
GO:0000912	biolink:NamedThing	assembly of actomyosin apparatus involved in cytokinesis	The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.	got7fsn_ti	formation of actomyosin apparatus involved in cytokinesis|cytokinesis, formation of actomyosin apparatus|actomyosin apparatus assembly involved in cytokinesis													biological_process											owl:Class	
GO:0045517	biolink:NamedThing	interleukin-20 receptor binding	Binding to an interleukin-20 receptor.	got7fsn_ti	IL-20|interleukin-20 receptor ligand													molecular_function											owl:Class	
GO:0090382	biolink:NamedThing	phagosome maturation	A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.	got7fsn_ti							tb	2010-10-19T11:10:34Z						biological_process											owl:Class	
GO:0034707	biolink:NamedThing	chloride channel complex	An ion channel complex through which chloride ions pass.	got7fsn_ti														cellular_component											owl:Class	
GO:0043997	biolink:NamedThing	histone acetyltransferase activity (H4-K12 specific)	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12).	got7fsn_ti	histone lysine N-acetyltransferase activity (H4-K12 specific)													molecular_function											owl:Class	
GO:0010485	biolink:NamedThing	H4 histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.	got7fsn_ti														molecular_function											owl:Class	
GO:0021534	biolink:NamedThing	cell proliferation in hindbrain	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.	got7fsn_ti														biological_process											owl:Class	
GO:0022879	biolink:NamedThing	protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	trehalose PTS transporter activity													molecular_function											owl:Class	
GO:0048734	biolink:NamedThing	proboscis morphogenesis	The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head.	got7fsn_ti														biological_process											owl:Class	
GO:0048149	biolink:NamedThing	behavioral response to ethanol	Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.	got7fsn_ti	behavioural response to ethanol													biological_process											owl:Class	
GO:0090529	biolink:NamedThing	cell septum assembly	The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.	got7fsn_ti	cell septum assembly involved in cell cycle cytokinesis						tb	2013-02-06T10:26:38Z			GO:0090530			biological_process											owl:Class	
GO:0032506	biolink:NamedThing	cytokinetic process	A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).	got7fsn_ti														biological_process											owl:Class	
GO:0004791	biolink:NamedThing	thioredoxin-disulfide reductase activity	Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide.	got7fsn_ti	thioredoxin reductase (NADPH) activity|thioredoxin disulfide reductase activity|NADPH2:oxidized thioredoxin oxidoreductase activity|thioredoxin-disulphide reductase activity|NADPH--thioredoxin reductase activity|thioredoxin:NADP+ oxidoreductase activity|NADPH:oxidized thioredoxin oxidoreductase activity|NADP--thioredoxin reductase activity											RHEA:20345|Reactome:R-HSA-1222485|Reactome:R-HSA-73646|Reactome:R-HSA-3323050|EC:1.8.1.9|KEGG_REACTION:R02016|MetaCyc:THIOREDOXIN-REDUCT-NADPH-RXN|Reactome:R-HSA-9617735		molecular_function											owl:Class	
GO:0004421	biolink:NamedThing	hydroxymethylglutaryl-CoA synthase activity	Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).	got7fsn_ti	acetoacetyl coenzyme A transacetase activity|3-hydroxy-3-methylglutaryl-CoA synthase activity|3-hydroxy-3-methylglutaryl coenzyme A synthetase activity|HMG-CoA synthase activity|beta-hydroxy-beta-methylglutaryl-CoA synthase activity|3-hydroxy-3-methylglutaryl CoA synthetase activity|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)|hydroxymethylglutaryl coenzyme A synthase activity|hydroxymethylglutaryl coenzyme A-condensing enzyme|3-hydroxy-3-methylglutaryl-coenzyme A synthase activity|acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity|3-hydroxy-3-methylglutaryl coenzyme A synthase activity|(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity				Note that this function was formerly EC:4.1.3.5.							Reactome:R-HSA-191323|KEGG_REACTION:R01978|RHEA:10188|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN|Reactome:R-HSA-73918|EC:2.3.3.10		molecular_function											owl:Class	
GO:0031613	biolink:NamedThing	nuclear proteasome regulatory particle, lid subcomplex	The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0120229	biolink:NamedThing	protein localization to motile cilium	A process in which a protein is transported to, or maintained in, a location within a motile cilium.	got7fsn_ti	protein localization to nonmotile primary cilium	https://github.com/geneontology/go-ontology/issues/19588					krc	2020-06-05T23:43:04Z						biological_process											owl:Class	
GO:0061512	biolink:NamedThing	protein localization to cilium	A process in which a protein is transported to, or maintained in, a location within a cilium.	got7fsn_ti							dph	2013-03-22T15:41:44Z						biological_process											owl:Class	
GO:0050588	biolink:NamedThing	apo-beta-carotenoid-14',13'-dioxygenase activity	Catalysis of the reaction: 8'-apo-beta-carotenol + O(2) = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal.	got7fsn_ti	apo-b-carotenoid-14',13'-dioxygenase activity|8'-apo-beta-carotenol:O2 oxidoreductase activity											MetaCyc:1.13.12.12-RXN|EC:1.13.11.67|KEGG_REACTION:R08889|RHEA:26023		molecular_function											owl:Class	
GO:0051219	biolink:NamedThing	phosphoprotein binding	Binding to a phosphorylated protein.	got7fsn_ti	phosphorylated protein binding													molecular_function											owl:Class	
GO:0048761	biolink:NamedThing	collenchyma cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.	got7fsn_ti														biological_process											owl:Class	
GO:0010090	biolink:NamedThing	trichome morphogenesis	The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	trichome cell morphogenesis during differentiation										GO:0048272			biological_process											owl:Class	
GO:0000904	biolink:NamedThing	cell morphogenesis involved in differentiation	The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	got7fsn_ti														biological_process											owl:Class	
GO:0018049	biolink:NamedThing	C-terminal peptidyl-serine amidation	The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0096		biological_process											owl:Class	
GO:0032777	biolink:NamedThing	Piccolo NuA4 histone acetyltransferase complex	A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.	got7fsn_ti														cellular_component											owl:Class	
GO:0035267	biolink:NamedThing	NuA4 histone acetyltransferase complex	A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).	got7fsn_ti	TIP60 histone acetylase complex|TIP60 histone acetyltransferase complex													cellular_component											owl:Class	
GO:0042696	biolink:NamedThing	menarche	The beginning of the menstrual cycle; the first menstrual cycle in an individual.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Menarche		biological_process											owl:Class	
GO:0022601	biolink:NamedThing	menstrual cycle phase	The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0046293	biolink:NamedThing	formaldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.	got7fsn_ti	formaldehyde anabolism|formaldehyde synthesis|methanal biosynthesis|formaldehyde formation|formaldehyde biosynthesis|methanal biosynthetic process													biological_process											owl:Class	
GO:0061037	biolink:NamedThing	negative regulation of cartilage development	Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	got7fsn_ti							dph	2010-02-09T03:41:35Z						biological_process											owl:Class	
GO:0061035	biolink:NamedThing	regulation of cartilage development	Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	got7fsn_ti							dph	2010-02-09T03:41:35Z						biological_process											owl:Class	
GO:0071567	biolink:NamedThing	UFM1 hydrolase activity	Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates.	got7fsn_ti							mah	2010-01-20T04:08:34Z						molecular_function											owl:Class	
GO:0019783	biolink:NamedThing	ubiquitin-like protein-specific protease activity	Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated.	got7fsn_ti	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway|small conjugating protein-specific protease activity|ubiquitin-like-protein-specific protease activity|ubiquitin-like specific protease activity|ubiquitin-specific protease activity involved in positive regulation of ERAD pathway										GO:1904455|GO:1904454			molecular_function											owl:Class	
GO:0000144	biolink:NamedThing	cellular bud neck septin ring	A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.	got7fsn_ti														cellular_component											owl:Class	
GO:0032161	biolink:NamedThing	cleavage apparatus septin structure	Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0070329	biolink:NamedThing	tRNA seleno-modification	The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule.	got7fsn_ti	tRNA base modification to selenouridine													biological_process											owl:Class	
GO:0001887	biolink:NamedThing	selenium compound metabolic process	The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.	got7fsn_ti	selenium metabolism|selenium compound metabolism|selenium metabolic process													biological_process											owl:Class	
GO:1990773	biolink:NamedThing	matrix metallopeptidase secretion	The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins.	got7fsn_ti	matrix metalloproteinase secretion|MMP secretion						sl	2015-06-15T19:12:06Z						biological_process											owl:Class	
GO:0035018	biolink:NamedThing	adult chitin-based cuticle pattern formation	The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.	got7fsn_ti	adult cuticle pattern formation													biological_process											owl:Class	
GO:0016801	biolink:NamedThing	hydrolase activity, acting on ether bonds	Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively.	got7fsn_ti												EC:3.3.-.-		molecular_function											owl:Class	
GO:0061808	biolink:NamedThing	negative regulation of DNA recombination at centromere	Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.	got7fsn_ti	negative regulation of centromeric recombination						dph	2016-11-10T15:24:50Z						biological_process											owl:Class	
GO:0045910	biolink:NamedThing	negative regulation of DNA recombination	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.	got7fsn_ti	down-regulation of DNA recombination|downregulation of DNA recombination|inhibition of DNA recombination|down regulation of DNA recombination													biological_process											owl:Class	
GO:0070792	biolink:NamedThing	Hulle cell development	The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.	got7fsn_ti	Hulle cell formation|Huelle cell development						mah	2009-07-08T02:54:30Z						biological_process											owl:Class	
GO:0061436	biolink:NamedThing	establishment of skin barrier	Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.	got7fsn_ti	skin barrier development|epithelial barrier development|establishment of epithelial barrier						dph	2012-03-02T09:14:26Z						biological_process											owl:Class	
GO:0033561	biolink:NamedThing	regulation of water loss via skin	A process that modulates the rate or extent of water loss from an organism via the skin.	got7fsn_ti	skin barrier function													biological_process											owl:Class	
GO:0018060	biolink:NamedThing	N-terminal peptidyl-cysteine deamination	The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.	got7fsn_ti														biological_process											owl:Class	
GO:0006487	biolink:NamedThing	protein N-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.	got7fsn_ti	N-glycan biosynthesis|N-glycan metabolism|protein amino acid N-linked glycosylation											RESID:AA0151|RESID:AA0156|RESID:AA0327		biological_process											owl:Class	
GO:0010881	biolink:NamedThing	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.	got7fsn_ti														biological_process											owl:Class	
GO:0010880	biolink:NamedThing	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.	got7fsn_ti														biological_process											owl:Class	
GO:0045276	biolink:NamedThing	plasma membrane respiratory chain complex III	A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Examples of this component are found in bacterial species.	got7fsn_ti	plasma membrane coenzyme Q-cytochrome c reductase complex|plasma membrane coenzyme Q-cytochrome c oxidoreductase complex|ubiquinol-cytochrome c oxidoreductase complex|ubiquinol-cytochrome-c reductase complex|plasma membrane cytochrome bc1 complex|plasma membrane ubiquinol-cytochrome-c reductase complex|respiratory chain complex III										GO:0045286			cellular_component											owl:Class	
GO:0098797	biolink:NamedThing	plasma membrane protein complex	Any protein complex that is part of the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0044187	biolink:NamedThing	host cell lysosome	A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions.	got7fsn_ti							jl	2009-10-15T03:26:00Z						cellular_component											owl:Class	
GO:0060366	biolink:NamedThing	lambdoid suture morphogenesis	The process in which the lambdoid suture is generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0047777	biolink:NamedThing	(S)-citramalyl-CoA lyase activity	Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate.	got7fsn_ti	(3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming)|(3S)-citramalyl-CoA lyase activity|citramalyl coenzyme A lyase activity|citramalyl-CoA lyase activity|(+)-CMA-CoA lyase activity|(3S)-citramalyl-CoA pyruvate-lyase activity											MetaCyc:CITRAMALYL-COA-LYASE-RXN|EC:4.1.3.25|KEGG_REACTION:R00237|RHEA:22612		molecular_function											owl:Class	
GO:0004615	biolink:NamedThing	phosphomannomutase activity	Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.	got7fsn_ti	mannose phosphomutase activity|D-mannose 1,6-phosphomutase activity|phosphomannose mutase activity|alpha-D-mannose 1,6-phosphomutase activity										GO:0008971	RHEA:11140|KEGG_REACTION:R01818|Reactome:R-HSA-3781926|MetaCyc:PHOSMANMUT-RXN|Reactome:R-HSA-446201|EC:5.4.2.8		molecular_function											owl:Class	
GO:1990028	biolink:NamedThing	intermediate voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded.	got7fsn_ti	R-type calcium channel						pr	2013-02-06T20:55:41Z						molecular_function											owl:Class	
GO:0050459	biolink:NamedThing	ethanolamine-phosphate phospho-lyase activity	Catalysis of the reaction: H(2)O + phosphoethanolamine = acetaldehyde + NH(4)(+) + phosphate.	got7fsn_ti	amino alcohol O-phosphate phospholyase activity|O-phosphoethanolamine-phospholyase activity|ethanolamine-phosphate phospho-lyase (deaminating)|O-phosphorylethanol-amine phospho-lyase activity|ethanolamine-phosphate phospho-lyase (deaminating; acetaldehyde-forming)											EC:4.2.3.2|Reactome:R-HSA-5696415|KEGG_REACTION:R00748|RHEA:17889|MetaCyc:ETHANOLAMINE-PHOSPHATE-PHOSPHO-LYASE-RXN		molecular_function											owl:Class	
GO:0075043	biolink:NamedThing	melanization of appressorium wall	The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium.	got7fsn_ti	maintenance of turgor in appressorium by melanization|melanization of appressorium to maintain turgor pressure	https://github.com/geneontology/go-ontology/issues/21505												biological_process											owl:Class	
GO:0043476	biolink:NamedThing	pigment accumulation	The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.	got7fsn_ti	pigment accumulation in response to external stimulus													biological_process											owl:Class	
GO:0001738	biolink:NamedThing	morphogenesis of a polarized epithelium	The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.	got7fsn_ti	epithelial polarization													biological_process											owl:Class	
GO:0030119	biolink:NamedThing	AP-type membrane coat adaptor complex	Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).	got7fsn_ti	clathrin adaptor													cellular_component											owl:Class	
GO:0044388	biolink:NamedThing	small protein activating enzyme binding	Binding to a small protein activating enzyme, such as ubiquitin-activating enzyme.	got7fsn_ti							jl	2011-12-15T04:28:17Z						molecular_function											owl:Class	
GO:0002108	biolink:NamedThing	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0000470	biolink:NamedThing	maturation of LSU-rRNA	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0070178	biolink:NamedThing	D-serine metabolic process	The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.	got7fsn_ti	D-serine metabolism													biological_process											owl:Class	
GO:0009069	biolink:NamedThing	serine family amino acid metabolic process	The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.	got7fsn_ti	serine family amino acid metabolism													biological_process											owl:Class	
GO:0071473	biolink:NamedThing	cellular response to cation stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.	got7fsn_ti							mah	2009-12-18T11:49:46Z						biological_process											owl:Class	
GO:0043157	biolink:NamedThing	response to cation stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.	got7fsn_ti														biological_process											owl:Class	
GO:0102382	biolink:NamedThing	rebaudioside B glucosyltransferase activity	Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose <=> rebaudioside A + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13518		molecular_function											owl:Class	
GO:0061284	biolink:NamedThing	specification of mesonephric proximal tubule identity	The process in which the proximal tubule of the mesonephric nephron acquires its identity.	got7fsn_ti							dph	2010-09-02T01:44:24Z						biological_process											owl:Class	
GO:0061282	biolink:NamedThing	specification of mesonephric nephron tubule identity	The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.	got7fsn_ti							dph	2010-09-02T01:37:44Z						biological_process											owl:Class	
GO:0120236	biolink:NamedThing	negative regulation of posttranslational protein targeting to membrane, translocation	Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane.	got7fsn_ti	negative regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation|negative regulation of posttranslational endoplasmic reticulum membrane protein translocation|negative regulation of N-terminal signal peptide-independent translocation into the ER	https://github.com/geneontology/go-ontology/issues/19791					krc	2020-08-03T17:12:53Z						biological_process											owl:Class	
GO:0097188	biolink:NamedThing	dentin mineralization	The process in which calcium salts are deposited into the calcareous tooth structure known as dentin.	got7fsn_ti	dentine mineralization						pr	2011-11-21T09:05:43Z						biological_process											owl:Class	
GO:0034505	biolink:NamedThing	tooth mineralization	The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.	got7fsn_ti	tooth calcification													biological_process											owl:Class	
GO:0090639	biolink:NamedThing	phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol	The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine.	got7fsn_ti							tb	2015-04-23T15:56:12Z						biological_process											owl:Class	
GO:0006656	biolink:NamedThing	phosphatidylcholine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	got7fsn_ti	phosphatidylcholine formation|phosphatidylcholine anabolism|phosphatidylcholine biosynthesis|phosphatidylcholine synthesis													biological_process											owl:Class	
GO:0106150	biolink:NamedThing	zearalenone biosynthetic process	The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals.	got7fsn_ti							hjd	2018-09-14T17:08:18Z						biological_process											owl:Class	
GO:0007388	biolink:NamedThing	posterior compartment specification	The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0007386	biolink:NamedThing	compartment pattern specification	The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.	got7fsn_ti	compartment specification													biological_process											owl:Class	
GO:0034949	biolink:NamedThing	1,1-dichloroethane reductive dehalogenase activity	Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl.	got7fsn_ti												UM-BBD_reactionID:r1008|EC:1.97.1.-		molecular_function											owl:Class	
GO:0017176	biolink:NamedThing	phosphatidylinositol N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol.	got7fsn_ti	UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-(N-acetyl-alpha-D-glucosaminyl)transferase activity|uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine alpha-1,6-acetyl-D-glucosaminyltransferase activity											EC:2.4.1.198|RHEA:14789|MetaCyc:2.4.1.198-RXN		molecular_function											owl:Class	
GO:0008912	biolink:NamedThing	lactaldehyde reductase activity	Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+.	got7fsn_ti	propanediol oxidoreductase activity|lactaldehyde:propanediol oxidoreductase activity|propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity|(R)- or (S)-propane-1,2-diol:NAD+ oxidoreductase activity											EC:1.1.1.77		molecular_function											owl:Class	
GO:0036483	biolink:NamedThing	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.	got7fsn_ti	endoplasmic reticulum stress-induced neuron apoptosis|ER stress-induced neuron intrinsic apoptotic signaling pathway|endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|ER stress-induced neuron apoptosis						bf	2014-08-14T13:33:23Z						biological_process											owl:Class	
GO:0070059	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.	got7fsn_ti	intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|apoptosis in response to ER stress|apoptosis in response to endoplasmic reticulum stress|apoptosis triggered by ER stress|endoplasmic reticulum stress-induced apoptosis|ER stress-induced apoptosis													biological_process											owl:Class	
GO:0060115	biolink:NamedThing	vestibular receptor cell fate commitment	The process in which a cell becomes committed to become a vestibular receptor cell.	got7fsn_ti	vestibular hair cell fate commitment													biological_process											owl:Class	
GO:0060120	biolink:NamedThing	inner ear receptor cell fate commitment	The process in which a cell becomes committed to become an inner ear receptor cell.	got7fsn_ti	inner ear hair cell fate commitment													biological_process											owl:Class	
GO:0035327	biolink:NamedThing	transcriptionally active chromatin	The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.	got7fsn_ti							bf	2010-02-26T10:23:02Z						cellular_component											owl:Class	
GO:0018822	biolink:NamedThing	nitrile hydratase activity	Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.	got7fsn_ti	L-NHase activity|aliphatic nitrile hydratase activity|NHase activity|3-cyanopyridine hydratase activity|acrylonitrile hydratase activity|nitrile hydro-lyase activity|H-NHase activity|aliphatic-amide hydro-lyase (nitrile-forming)											EC:4.2.1.84|MetaCyc:NITRILE-HYDRATASE-RXN|RHEA:12673|UM-BBD_enzymeID:e0067		molecular_function											owl:Class	
GO:0046353	biolink:NamedThing	aminoglycoside 3-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.	got7fsn_ti	acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity|acetyl-CoA:gentamicin-C N3'-acetyltransferase activity|3-N-aminoglycoside acetyltransferase activity|aminoglycoside acetyltransferase AAC(3)-I activity|aminoglycoside acetyltransferase AAC(3)-1|gentamycin 3'-N-acetyltransferase activity|gentamicin acetyltransferase I activity|gentamicin-(3)-N-acetyltransferase activity|gentamycin acetyltransferase I|gentamicin 3'-N-acetyltransferase activity|3'-aminoglycoside acetyltransferase activity										GO:0016991	MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.60|EC:2.3.1.81|MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0004661	biolink:NamedThing	protein geranylgeranyltransferase activity	Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein.	got7fsn_ti	protein-cysteine geranylgeranyltransferase activity										GO:0018224			molecular_function											owl:Class	
GO:0008318	biolink:NamedThing	protein prenyltransferase activity	Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.	got7fsn_ti											GO:0008244			molecular_function											owl:Class	
GO:0103069	biolink:NamedThing	17-hydroxyprogesterone 21-hydroxylase activity	Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti												MetaCyc:RXN66-356|RHEA:50308		molecular_function											owl:Class	
GO:0004509	biolink:NamedThing	steroid 21-monooxygenase activity	Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O(2) = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H(2)O.	got7fsn_ti	cytochrome P450 CYP21A1|steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)|21-hydroxylase activity|cytochrome p450 XXIA1 activity|steroid 21-hydroxylase activity											Reactome:R-HSA-193981|EC:1.14.14.16|Reactome:R-HSA-193964|MetaCyc:STEROID-21-MONOOXYGENASE-RXN|RHEA:65612|Reactome:R-HSA-5601976		molecular_function											owl:Class	
GO:0002770	biolink:NamedThing	T cell inhibitory signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response.	got7fsn_ti	T-lymphocyte inhibitory signaling pathway|T cell inhibitory signalling pathway|T-cell inhibitory signaling pathway|T lymphocyte inhibitory signaling pathway													biological_process											owl:Class	
GO:0009636	biolink:NamedThing	response to toxic substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.	got7fsn_ti	detoxification response|toxin resistance|toxin susceptibility/resistance													biological_process											owl:Class	
GO:0008579	biolink:NamedThing	JUN kinase phosphatase activity	Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0008138	biolink:NamedThing	protein tyrosine/serine/threonine phosphatase activity	Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	got7fsn_ti	dual-specificity protein phosphatase	https://github.com/geneontology/go-ontology/issues/12183			Note that this term applies only to free amino acids. Consider 'protein serine/threonine phosphatase activity' or 'protein tyrosine/serine/threonine phosphatase activity' if you want to annotate a protein phosphatase.							Reactome:R-HSA-5675376|Reactome:R-HSA-5675373|Reactome:R-HSA-9652816		molecular_function											owl:Class	
GO:0016472	biolink:NamedThing	sodium ion-transporting two-sector ATPase complex	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis.	got7fsn_ti	sodium-transporting two-sector ATPase complex													cellular_component											owl:Class	
GO:0042728	biolink:NamedThing	flavin-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.	got7fsn_ti	riboflavin and derivative catabolism|vitamin B2 and derivative catabolic process|flavin-containing compound catabolic process degradation|vitamin B2 and derivative catabolism|flavin-containing compound catabolic process breakdown|flavin-containing compound catabolism|riboflavin and derivative catabolic process													biological_process											owl:Class	
GO:0005821	biolink:NamedThing	intermediate layer of spindle pole body	Structure between the central and outer plaques of the spindle pole body.	got7fsn_ti														cellular_component											owl:Class	
GO:0050491	biolink:NamedThing	sulcatone reductase activity	Catalysis of the reaction: NAD(+) + sulcatol = H(+) + NADH + sulcatone.	got7fsn_ti	sulcatol:NAD+ oxidoreductase activity											MetaCyc:1.1.1.260-RXN|EC:1.1.1.260|KEGG_REACTION:R05678|RHEA:24484		molecular_function											owl:Class	
GO:0090660	biolink:NamedThing	cerebrospinal fluid circulation	The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional.	got7fsn_ti	CSF circulation|CSF flow|cerebrospinal fluid flow						tb	2015-09-11T15:49:59Z						biological_process											owl:Class	
GO:0102456	biolink:NamedThing	cyanidin 3-O-glucoside 5-O-glucosyltransferase (sinapoyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-sinapoyl-beta-D-glucose <=> cyanin betaine + trans-sinapate + H+.	got7fsn_ti												MetaCyc:RXN-13967		molecular_function											owl:Class	
GO:0060943	biolink:NamedThing	neural crest-derived cardiac fibroblast cell development	The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T02:31:24Z						biological_process											owl:Class	
GO:0060936	biolink:NamedThing	cardiac fibroblast cell development	The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T01:23:03Z						biological_process											owl:Class	
GO:0030351	biolink:NamedThing	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate.	got7fsn_ti												Reactome:R-HSA-1855163		molecular_function											owl:Class	
GO:0072549	biolink:NamedThing	monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity	Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O.	got7fsn_ti							mah	2011-01-25T02:58:04Z						molecular_function											owl:Class	
GO:0072533	biolink:NamedThing	tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity	Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives.	got7fsn_ti					Note that the overall reaction representing three successive executions of this activity is N1,N5,N10-tricoumaroyl spermidine + 3 NADPH + 3 O2 = N1,N5,N10-tricaffeoyl spermidine + 3 NADP+ + 3 H2O; this corresponds to the MetaCyc reaction RXN-11260 (http://biocyc.org/META/NEW-IMAGE?type=REACTION&object=RXN-11260).		mah	2011-01-12T02:03:07Z						molecular_function											owl:Class	
GO:0021820	biolink:NamedThing	extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration	The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells.	got7fsn_ti	organization of extracellular matrix in the marginal zone involved in cerebral cortex glial-mediated radial migration|extracellular matrix organisation in marginal zone involved in cerebral cortex radial glia guided migration													biological_process											owl:Class	
GO:0102671	biolink:NamedThing	6a-hydroxymaackiain-3-O-methyltransferase activity	Catalysis of the reaction: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine  <=> H+ + (+)-pisatin + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.270|RHEA:35471|MetaCyc:RXN-4002		molecular_function											owl:Class	
GO:0046629	biolink:NamedThing	gamma-delta T cell activation	The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti	gamma-delta T-lymphocyte activation|gamma-delta T lymphocyte activation|gamma-delta T-cell activation													biological_process											owl:Class	
GO:0015800	biolink:NamedThing	acidic amino acid transport	The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0006865	biolink:NamedThing	amino acid transport	The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti											GO:0006866			biological_process											owl:Class	
GO:0098005	biolink:NamedThing	viral head-tail joining	Process by which virus heads and tails are attached to each other.	got7fsn_ti	phage head tail joining|virus head-tail joining						bm	2012-07-18T16:11:59Z						biological_process											owl:Class	
GO:0061584	biolink:NamedThing	hypocretin secretion	The controlled release of hypocretin from a cell or a tissue.	got7fsn_ti	orexin secretion						dph	2013-12-26T10:07:38Z						biological_process											owl:Class	
GO:0002790	biolink:NamedThing	peptide secretion	The controlled release of a peptide from a cell or a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0044696	biolink:NamedThing	killing by virus of host cell by post-segregational killing	The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.	got7fsn_ti	killing by virus of host cell by toxin-antitoxin system|killing by virus of host cell by PSK				Note that this process occurs after the cell division partitioning event.		jl	2012-08-16T13:58:18Z						biological_process											owl:Class	
GO:0039633	biolink:NamedThing	killing by virus of host cell	Any process mediated by a virus that results in the death of a cell in the host organism.	got7fsn_ti	killing by virus of host cells|killing by phage of host cells						bf	2012-08-10T14:44:40Z						biological_process											owl:Class	
GO:0043063	biolink:NamedThing	intercellular bridge organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.	got7fsn_ti	intercellular bridge organization and biogenesis|intercellular bridge organisation													biological_process											owl:Class	
GO:0043062	biolink:NamedThing	extracellular structure organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.	got7fsn_ti	extracellular structure organisation|extracellular structure organization and biogenesis													biological_process											owl:Class	
GO:0048744	biolink:NamedThing	negative regulation of skeletal muscle fiber development	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	got7fsn_ti	negative regulation of skeletal muscle fibre development|down regulation of skeletal muscle fiber development|negative regulation of skeletal myofiber development|negative regulation of skeletal myofibre development|downregulation of skeletal muscle fiber development|down-regulation of skeletal muscle fiber development|inhibition of skeletal muscle fiber development													biological_process											owl:Class	
GO:0051154	biolink:NamedThing	negative regulation of striated muscle cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.	got7fsn_ti	down regulation of striated muscle cell differentiation|inhibition of striated muscle cell differentiation|down-regulation of striated muscle cell differentiation|downregulation of striated muscle cell differentiation													biological_process											owl:Class	
GO:0099645	biolink:NamedThing	neurotransmitter receptor localization to postsynaptic specialization membrane	A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).	got7fsn_ti	neurotransmitter receptor localisation in postsynaptic specialization membrane													biological_process											owl:Class	
GO:0099072	biolink:NamedThing	regulation of postsynaptic membrane neurotransmitter receptor levels	Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0060717	biolink:NamedThing	chorion development	The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.	got7fsn_ti							dph	2009-06-11T02:37:50Z						biological_process											owl:Class	
GO:0042180	biolink:NamedThing	cellular ketone metabolic process	The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.	got7fsn_ti	ketone metabolism													biological_process											owl:Class	
GO:0045325	biolink:NamedThing	peptidyl-tryptophan hydroxylation	The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan.	got7fsn_ti												RESID:AA0322		biological_process											owl:Class	
GO:0120103	biolink:NamedThing	centriolar subdistal appendage	A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68.	got7fsn_ti	subdistal appendage of mother centriole|subdistal appendage of centriole|subdistal appendage of basal body						krc	2017-10-10T15:31:40Z						cellular_component											owl:Class	
GO:0000113	biolink:NamedThing	nucleotide-excision repair factor 4 complex	One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p.	got7fsn_ti	NEF4 complex				Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.									cellular_component											owl:Class	
GO:0030857	biolink:NamedThing	negative regulation of epithelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.	got7fsn_ti	inhibition of epithelial cell differentiation|down-regulation of epithelial cell differentiation|downregulation of epithelial cell differentiation|down regulation of epithelial cell differentiation													biological_process											owl:Class	
GO:0030856	biolink:NamedThing	regulation of epithelial cell differentiation	Any process that modulates the frequency, rate or extent of epithelial cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0031692	biolink:NamedThing	alpha-1B adrenergic receptor binding	Binding to an alpha-1B adrenergic receptor.	got7fsn_ti	alpha-1B adrenergic receptor ligand													molecular_function											owl:Class	
GO:0033038	biolink:NamedThing	bitter taste receptor activity	Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste.	got7fsn_ti														molecular_function											owl:Class	
GO:0072149	biolink:NamedThing	glomerular visceral epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.	got7fsn_ti	podocyte cell fate commitment						mah	2010-02-24T02:08:03Z						biological_process											owl:Class	
GO:0003172	biolink:NamedThing	sinoatrial valve development	The progression of the sinoatrial valve over time, from its formation to the mature structure.	got7fsn_ti	SA valve development						dph	2009-10-08T11:15:39Z						biological_process											owl:Class	
GO:0003170	biolink:NamedThing	heart valve development	The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.	got7fsn_ti	cardiac valve development						dph	2009-10-08T10:50:09Z						biological_process											owl:Class	
GO:0071489	biolink:NamedThing	cellular response to red or far red light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti							mah	2009-12-18T02:18:25Z						biological_process											owl:Class	
GO:0031751	biolink:NamedThing	D4 dopamine receptor binding	Binding to a D4 dopamine receptor.	got7fsn_ti	D4 dopamine receptor ligand													molecular_function											owl:Class	
GO:0050780	biolink:NamedThing	dopamine receptor binding	Binding to a dopamine receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0032838	biolink:NamedThing	plasma membrane bounded cell projection cytoplasm	All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.	got7fsn_ti														cellular_component											owl:Class	
GO:0099568	biolink:NamedThing	cytoplasmic region	Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.	got7fsn_ti														cellular_component											owl:Class	
GO:0060462	biolink:NamedThing	lung lobe development	The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.	got7fsn_ti														biological_process											owl:Class	
GO:0043792	biolink:NamedThing	enamidase activity	Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H(2)O = 2-formylglutarate + NH(4)(+).	got7fsn_ti	6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase activity											KEGG_REACTION:R07984|EC:3.5.2.18|MetaCyc:3.5.2.18-RXN|RHEA:17209		molecular_function											owl:Class	
GO:0009486	biolink:NamedThing	cytochrome bo3 ubiquinol oxidase activity	Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space].	got7fsn_ti	cytochrome o ubiquinol oxidase activity|cytochrome bo(3) oxidase|cytochrome bo oxidase	https://github.com/geneontology/go-ontology/issues/20924									GO:0008827	RHEA:30251|EC:7.1.1.3|MetaCyc:RXN0-5268|TC:3.D.4.5.1		molecular_function											owl:Class	
GO:0009055	biolink:NamedThing	electron transfer activity	Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.	got7fsn_ti	electron transporter activity|electron carrier|electron acceptor activity|electron donor activity	https://github.com/geneontology/go-ontology/issues/21334			Note that this term should only be be used for electron transfer that generates a transmembrane electrochemical gradient, e.g. components of the respiratory or photosynthetic electron transport chain.						GO:0009053|GO:0009054	Reactome:R-HSA-169260|Reactome:R-HSA-2564826		molecular_function											owl:Class	
GO:0044199	biolink:NamedThing	host cell nuclear envelope	The double lipid bilayer enclosing the host nucleus and separating its contents from the rest of the host cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).	got7fsn_ti							jl	2009-10-21T10:56:11Z						cellular_component											owl:Class	
GO:0097610	biolink:NamedThing	cell surface furrow	A furrow that may be found on the cell surface. Examples include the cingulum and sulcus found in some dinoflagellates.	got7fsn_ti	cell surface groove|furrow|groove						pr	2014-06-09T11:22:38Z						cellular_component											owl:Class	
GO:0052130	biolink:NamedThing	negative aerotaxis	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen.	got7fsn_ti														biological_process											owl:Class	
GO:0050919	biolink:NamedThing	negative chemotaxis	The directed movement of a motile cell or organism towards a lower concentration of a chemical.	got7fsn_ti	chemoaversion|chemorepulsion													biological_process											owl:Class	
GO:0038156	biolink:NamedThing	interleukin-3-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-3 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-3-mediated signaling pathway|interleukin-3-mediated signalling pathway						bf	2012-05-11T11:50:42Z						biological_process											owl:Class	
GO:1990299	biolink:NamedThing	Bub1-Bub3 complex localization to kinetochore	A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore.	got7fsn_ti							al	2014-02-26T09:29:13Z						biological_process											owl:Class	
GO:0090527	biolink:NamedThing	actin filament reorganization	A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments.	got7fsn_ti							tb	2013-01-23T10:27:44Z						biological_process											owl:Class	
GO:0106388	biolink:NamedThing	18S rRNA aminocarboxypropyltransferase activity	Catalysis of the reaction: N1-methylpseudouridine in 18S rRNA + S-adenosyl-L-methionine = H+ + N1-methyl-N3-[(3S)-3-amino-3-carboxypropyl]pseudouridine in 18S rRNA + S-methyl-5'-thioadenosine.	got7fsn_ti							hjd	2021-07-13T14:01:28Z				RHEA:63296		molecular_function											owl:Class	
GO:0140102	biolink:NamedThing	catalytic activity, acting on a rRNA	Catalytic activity that acts to modify a ribosomal RNA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14225					pg	2017-09-15T19:00:57Z						molecular_function											owl:Class	
GO:0043126	biolink:NamedThing	regulation of 1-phosphatidylinositol 4-kinase activity	Any process that modulates the activity of the enzyme 1-phosphatidylinositol 4-kinase.	got7fsn_ti	regulation of PI4K activity													biological_process											owl:Class	
GO:0043550	biolink:NamedThing	regulation of lipid kinase activity	Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.	got7fsn_ti														biological_process											owl:Class	
GO:0009850	biolink:NamedThing	auxin metabolic process	The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth.	got7fsn_ti	auxin metabolism													biological_process											owl:Class	
GO:0002002	biolink:NamedThing	regulation of angiotensin levels in blood	The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation.	got7fsn_ti	regulation of blood angiotensin level|control of angiotensin levels in blood|control of blood angiotensin level	https://github.com/geneontology/go-ontology/issues/15424												biological_process											owl:Class	
GO:0010817	biolink:NamedThing	regulation of hormone levels	Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.	got7fsn_ti														biological_process											owl:Class	
GO:0004098	biolink:NamedThing	cerebroside-sulfatase activity	Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate.	got7fsn_ti	arylsulfatase A activity|cerebroside-sulphatase activity|cerebroside sulfate sulfatase activity|cerebroside-3-sulfate 3-sulfohydrolase activity											Reactome:R-HSA-1606807|EC:3.1.6.8|RHEA:21300|MetaCyc:CEREBROSIDE-SULFATASE-RXN		molecular_function											owl:Class	
GO:0003848	biolink:NamedThing	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+).	got7fsn_ti	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity|H2-pteridine-CH2OH pyrophosphokinase activity|7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity|ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity|7,8-dihydroxymethylpterin-pyrophosphokinase activity|6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity|6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity|hydroxymethyldihydropteridine pyrophosphokinase activity|7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity|HPPK											MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN|RHEA:11412|KEGG_REACTION:R03503|EC:2.7.6.3		molecular_function											owl:Class	
GO:0052091	biolink:NamedThing	modulation by symbiont of nutrient release from host	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0044003	biolink:NamedThing	modulation by symbiont of host process	The process in which a symbiont organism effects a change in the structure or processes of its host organism.	got7fsn_ti	modulation by symbiont of host system process|disruption by symbiont of host cell|pathogenesis|modification by symbiont of host biological process|regulation by symbiont of host system process|modification by symbiont of host morphology or physiology	https://github.com/geneontology/go-ontology/issues/18719									GO:0044055|GO:0044004			biological_process											owl:Class	
GO:0001588	biolink:NamedThing	dopamine neurotransmitter receptor activity, coupled via Gs	Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.	got7fsn_ti	dopamine D1 receptor activity|dopamine D5 receptor activity										GO:0001590|GO:0001589			molecular_function											owl:Class	
GO:0004952	biolink:NamedThing	dopamine neurotransmitter receptor activity	Combining with the neurotransmitter dopamine to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0002489	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-dependent|TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway|TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway													biological_process											owl:Class	
GO:0002488	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway													biological_process											owl:Class	
GO:0000473	biolink:NamedThing	maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0035758	biolink:NamedThing	chemokine (C-C motif) ligand 21 binding	Binding to chemokine (C-C motif) ligand 21.	got7fsn_ti	CCL21 binding						bf	2011-03-25T02:03:53Z						molecular_function											owl:Class	
GO:0042038	biolink:NamedThing	peptidyl-histidine methylation, to form tele-methylhistidine	The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine).	got7fsn_ti	peptidyl-histidine tele-methylation										GO:0042261	RESID:AA0317		biological_process											owl:Class	
GO:0071721	biolink:NamedThing	sodium-independent thromboxane transport	The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.	got7fsn_ti							mah	2010-03-10T03:10:45Z						biological_process											owl:Class	
GO:0035071	biolink:NamedThing	salivary gland cell autophagic cell death	The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.	got7fsn_ti	salivary gland cell death|autophagic cell death of salivary gland cells|salivary gland cell programmed cell death by autophagy|programmed cell death of salivary gland cells by autophagy													biological_process											owl:Class	
GO:0035781	biolink:NamedThing	CD86 biosynthetic process	The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.	got7fsn_ti	CD86 synthesis|CD86 formation|CD86 biosynthesis|CD86 anabolism						bf	2011-04-04T11:20:40Z						biological_process											owl:Class	
GO:0009752	biolink:NamedThing	detection of salicylic acid stimulus	The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of salicylic acid stimulus													biological_process											owl:Class	
GO:0009751	biolink:NamedThing	response to salicylic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.	got7fsn_ti	response to salicylate|response to salicylic acid stimulus													biological_process											owl:Class	
GO:0009525	biolink:NamedThing	phragmosome	A flattened membranous vesicle containing cell wall components.	got7fsn_ti												Wikipedia:Phragmosome		cellular_component											owl:Class	
GO:0044784	biolink:NamedThing	metaphase/anaphase transition of cell cycle	The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.	got7fsn_ti							jl	2013-05-02T13:09:34Z						biological_process											owl:Class	
GO:0033045	biolink:NamedThing	regulation of sister chromatid segregation	Any process that modulates the frequency, rate or extent of sister chromatid segregation.	got7fsn_ti														biological_process											owl:Class	
GO:0007460	biolink:NamedThing	R8 cell fate commitment	The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium.	got7fsn_ti	restriction of R8 fate										GO:0007461			biological_process											owl:Class	
GO:0001752	biolink:NamedThing	compound eye photoreceptor fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.	got7fsn_ti											GO:0007459			biological_process											owl:Class	
GO:0072515	biolink:NamedThing	trehalose transport in response to desiccation	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water.	got7fsn_ti							mah	2010-12-21T11:30:31Z						biological_process											owl:Class	
GO:0072514	biolink:NamedThing	trehalose transport in response to water deprivation	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water.	got7fsn_ti							mah	2010-12-21T11:26:14Z						biological_process											owl:Class	
GO:0034356	biolink:NamedThing	NAD biosynthesis via nicotinamide riboside salvage pathway	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.	got7fsn_ti	nicotinamide riboside salvage pathway|NR salvage pathway													biological_process											owl:Class	
GO:0009435	biolink:NamedThing	NAD biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.	got7fsn_ti	oxidized nicotinamide adenine dinucleotide biosynthesis|reduced NAD biosynthesis|oxidized nicotinamide adenine dinucleotide biosynthetic process|nicotinamide adenine dinucleotide biosynthetic process|NAD (oxidized) biosynthesis|nicotinamide adenine dinucleotide biosynthesis|NADH biosynthetic process|NAD (reduced) biosynthetic process|reduced nicotinamide adenine dinucleotide biosynthesis|reduced nicotinamide adenine dinucleotide biosynthetic process|NAD anabolism|NAD formation|NAD (oxidized) biosynthetic process|NAD (reduced) biosynthesis|oxidized NAD biosynthesis|oxidized NAD biosynthetic process|NAD synthesis|NAD biosynthesis|NADH biosynthesis|reduced NAD biosynthetic process										GO:0006736			biological_process											owl:Class	
GO:0043713	biolink:NamedThing	(R)-2-hydroxyisocaproate dehydrogenase activity	Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+.	got7fsn_ti														molecular_function											owl:Class	
GO:0050908	biolink:NamedThing	detection of light stimulus involved in visual perception	The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.	got7fsn_ti	sensory detection of light stimulus during visual perception|sensory detection of light during visual perception|sensory transduction of light stimulus during visual perception|sensory transduction of light during visual perception|visual perception, sensory transduction of light stimulus|visual perception, sensory transduction during perception of light|visual perception, detection of light stimulus													biological_process											owl:Class	
GO:0031865	biolink:NamedThing	EP2 subtype prostaglandin E2 receptor binding	Binding to an EP2 subtype prostaglandin E2 receptor.	got7fsn_ti	EP2 subtype prostaglandin E2 receptor ligand|prostanoid EP2 receptor binding													molecular_function											owl:Class	
GO:0039702	biolink:NamedThing	viral budding via host ESCRT complex	Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process.	got7fsn_ti	host-assisted viral budding|viral budding through the ESCRT machinery						bf	2013-11-06T16:51:53Z				VZ:1536		biological_process											owl:Class	
GO:0046755	biolink:NamedThing	viral budding	A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.	got7fsn_ti	virus budding|viral capsid envelopment|virion budding										GO:0046744	VZ:1947		biological_process											owl:Class	
GO:0031104	biolink:NamedThing	dendrite regeneration	The regrowth of dendrites in response to their loss or damage.	got7fsn_ti														biological_process											owl:Class	
GO:0016358	biolink:NamedThing	dendrite development	The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0004140	biolink:NamedThing	dephospho-CoA kinase activity	Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+).	got7fsn_ti	3'-dephospho-CoA kinase activity|ATP:dephospho-CoA 3'-phosphotransferase activity|dephosphocoenzyme A kinase (phosphorylating)|dephosphocoenzyme A kinase activity											RHEA:18245|KEGG_REACTION:R00130|MetaCyc:DEPHOSPHOCOAKIN-RXN|EC:2.7.1.24|Reactome:R-HSA-196773		molecular_function											owl:Class	
GO:0072233	biolink:NamedThing	metanephric thick ascending limb development	The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.	got7fsn_ti	metanephric TAL development						mah	2010-03-18T03:39:36Z						biological_process											owl:Class	
GO:0072023	biolink:NamedThing	thick ascending limb development	The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.	got7fsn_ti	TAL development						mah	2010-01-25T02:39:51Z			GO:0072026			biological_process											owl:Class	
GO:1902463	biolink:NamedThing	protein localization to cell leading edge	A process in which a protein is transported to, or maintained in, a location within a cell leading edge.	got7fsn_ti	protein localization in cell leading edge|protein localisation in cell leading edge|protein localisation to cell leading edge						jl	2013-10-22T12:36:07Z						biological_process											owl:Class	
GO:0005093	biolink:NamedThing	Rab GDP-dissociation inhibitor activity	Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding.	got7fsn_ti														molecular_function											owl:Class	
GO:0043955	biolink:NamedThing	3-hydroxypropionyl-CoA synthetase activity	Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate.	got7fsn_ti	acetyl-coenzyme A synthetase/GroES-like domain|enoyl-CoA hydratase/isomerase|acetyl-coenzyme A synthetase|AMP-dependent synthetase and ligase|3-hydroxy propionyl-CoA synthetase activity|AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase				Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.							RHEA:26534|EC:6.2.1.36		molecular_function											owl:Class	
GO:0051826	biolink:NamedThing	negative regulation of synapse structural plasticity	Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity.	got7fsn_ti	down regulation of synapse structural plasticity|downregulation of synapse structural plasticity|inhibition of synapse structural plasticity|down-regulation of synapse structural plasticity													biological_process											owl:Class	
GO:0051129	biolink:NamedThing	negative regulation of cellular component organization	Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.	got7fsn_ti	negative regulation of cell organisation|downregulation of cell organization|down-regulation of cell organization|inhibition of cell organization|negative regulation of cellular component organization and biogenesis|down regulation of cell organization													biological_process											owl:Class	
GO:0035660	biolink:NamedThing	MyD88-dependent toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	got7fsn_ti	MyD88-dependent toll-like receptor 4 signalling pathway|MyD88-dependent TLR4 signaling pathway						bf	2011-02-01T10:10:04Z						biological_process											owl:Class	
GO:0034142	biolink:NamedThing	toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.	got7fsn_ti	TLR4 signaling pathway|toll-like receptor 4 signalling pathway													biological_process											owl:Class	
GO:0015367	biolink:NamedThing	oxoglutarate:malate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).	got7fsn_ti	2-oxoglutarate/malate carrier protein											Reactome:R-HSA-376851|Reactome:R-HSA-198440		molecular_function											owl:Class	
GO:0015140	biolink:NamedThing	malate transmembrane transporter activity	Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.	got7fsn_ti	dicarboxylate (succinate/fumarate/malate) antiporter activity													molecular_function											owl:Class	
GO:0006903	biolink:NamedThing	vesicle targeting	The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.	got7fsn_ti														biological_process											owl:Class	
GO:0019887	biolink:NamedThing	protein kinase regulator activity	Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0019207	biolink:NamedThing	kinase regulator activity	Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0033113	biolink:NamedThing	cyanelle membrane	Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0016590	biolink:NamedThing	ACF complex	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.	got7fsn_ti	ATP-utilizing chromatin assembly and remodeling factor complex													cellular_component											owl:Class	
GO:0034889	biolink:NamedThing	endosulfan hemisulfate sulfatase activity	Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate.	got7fsn_ti												UM-BBD_reactionID:r1384		molecular_function											owl:Class	
GO:0016787	biolink:NamedThing	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.	got7fsn_ti												Reactome:R-HSA-2029475|Reactome:R-HSA-6788295|Reactome:R-HSA-5694583|Reactome:R-HSA-1236938|Reactome:R-HSA-8938314|Reactome:R-HSA-5695964|EC:3.-.-.-|Reactome:R-HSA-8952137|Reactome:R-HSA-6786190		molecular_function											owl:Class	
GO:0070253	biolink:NamedThing	somatostatin secretion	The regulated release of somatostatin from secretory granules in the D cells of the pancreas.	got7fsn_ti														biological_process											owl:Class	
GO:0060430	biolink:NamedThing	lung saccule development	The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.	got7fsn_ti	lung saccular development													biological_process											owl:Class	
GO:0098753	biolink:NamedThing	anchored component of the cytoplasmic side of the plasma membrane	The component of the plasma membrane consisting of gene products and protein complexes with covalently attached hydrophobic anchors products that penetrate only the cytoplasmic side of the membrane.	got7fsn_ti					Examples include many myristoylated proteins.									cellular_component											owl:Class	
GO:0031235	biolink:NamedThing	intrinsic component of the cytoplasmic side of the plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only.	got7fsn_ti	intrinsic to internal side of plasma membrane|intrinsic to internal leaflet of plasma membrane|intrinsic to cytoplasmic side of plasma membrane													cellular_component											owl:Class	
GO:0045606	biolink:NamedThing	positive regulation of epidermal cell differentiation	Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.	got7fsn_ti	positive regulation of hypodermal cell differentiation|upregulation of epidermal cell differentiation|up-regulation of epidermal cell differentiation|stimulation of epidermal cell differentiation|activation of epidermal cell differentiation|up regulation of epidermal cell differentiation													biological_process											owl:Class	
GO:0045604	biolink:NamedThing	regulation of epidermal cell differentiation	Any process that modulates the frequency, rate or extent of epidermal cell differentiation.	got7fsn_ti	regulation of hypodermal cell differentiation													biological_process											owl:Class	
GO:0035235	biolink:NamedThing	ionotropic glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	ionotropic glutamate receptor signalling pathway													biological_process											owl:Class	
GO:0007215	biolink:NamedThing	glutamate receptor signaling pathway	A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	glutamate signaling pathway|glutamate signalling pathway													biological_process											owl:Class	
GO:0031672	biolink:NamedThing	A band	The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.	got7fsn_ti	Q disc|transverse disc|A disc|anisotropic disc											Wikipedia:Sarcomere#bands		cellular_component											owl:Class	
GO:0010172	biolink:NamedThing	embryonic body morphogenesis	The process in which the anatomical structures of the embryonic soma are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0010171	biolink:NamedThing	body morphogenesis	The process in which the anatomical structures of the soma are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0010478	biolink:NamedThing	chlororespiration	A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool.	got7fsn_ti														biological_process											owl:Class	
GO:0022904	biolink:NamedThing	respiratory electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.	got7fsn_ti	dihydrolipoylprotein reduction|electron transfer|dihydrolipoamide reduction|oxidized glutathione reduction|dihydrobiopterin reduction|dihydropteridine reduction|protein-disulfide reduction|6-phosphofructokinase reduction|other pathways of electron transport											Wikipedia:Electron_transfer		biological_process											owl:Class	
GO:0042588	biolink:NamedThing	zymogen granule	A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.	got7fsn_ti														cellular_component											owl:Class	
GO:0050611	biolink:NamedThing	arsenate reductase (azurin) activity	Catalysis of the reaction: H(2)O + arsenite + 2 oxidized azurin = 2 H(+) + 2 reduced azurin + arsenate.	got7fsn_ti	arsenite:azurin oxidoreductase activity|arsenite oxidase activity										GO:0018691	UM-BBD_reactionID:r0634|RHEA:18701|MetaCyc:1.20.98.1-RXN|EC:1.20.9.1		molecular_function											owl:Class	
GO:0052882	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein.	got7fsn_ti												EC:1.20.9.-		molecular_function											owl:Class	
GO:0042251	biolink:NamedThing	maintenance of polarity of larval imaginal disc epithelium	The maintenance of an established polarized larval imaginal disc epithelium.	got7fsn_ti														biological_process											owl:Class	
GO:0016336	biolink:NamedThing	establishment or maintenance of polarity of larval imaginal disc epithelium	Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.	got7fsn_ti														biological_process											owl:Class	
GO:0007073	biolink:NamedThing	positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	got7fsn_ti	activation of transcription on exit from mitosis, from RNA polymerase I promoter|activation of transcription on exit from mitosis, from Pol I promoter													biological_process											owl:Class	
GO:0033820	biolink:NamedThing	DNA alpha-glucosyltransferase activity	Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.	got7fsn_ti	uridine diphosphoglucose-deoxyribonucleate alpha-glucosyltransferase activity|UDP-glucose:DNA alpha-D-glucosyltransferase activity|T4-HMC-alpha-glucosyl transferase activity|UDPglucose-DNA alpha-glucosyltransferase activity|T6-HMC-alpha-glucosyl transferase activity|T2-HMC-alpha-glucosyl transferase activity											MetaCyc:2.4.1.26-RXN|EC:2.4.1.26		molecular_function											owl:Class	
GO:0097310	biolink:NamedThing	cap2 mRNA methylation	Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA.	got7fsn_ti	cap2 mRNA capping						pr	2012-05-23T04:05:07Z						biological_process											owl:Class	
GO:0036451	biolink:NamedThing	cap mRNA methylation	Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA.	got7fsn_ti							bf	2013-11-06T14:36:00Z						biological_process											owl:Class	
GO:0048873	biolink:NamedThing	homeostasis of number of cells within a tissue	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0045545	biolink:NamedThing	syndecan binding	Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.	got7fsn_ti														molecular_function											owl:Class	
GO:0043394	biolink:NamedThing	proteoglycan binding	Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	got7fsn_ti														molecular_function											owl:Class	
GO:0071766	biolink:NamedThing	Actinobacterium-type cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.	got7fsn_ti							mah	2010-03-29T04:12:51Z						biological_process											owl:Class	
GO:0009273	biolink:NamedThing	peptidoglycan-based cell wall biogenesis	The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli.	got7fsn_ti	cell envelope biosynthesis|cell wall assembly|cell wall biosynthetic process|cell wall formation|cell wall synthesis|cell wall anabolism|cell envelope biosynthetic process													biological_process											owl:Class	
GO:0051286	biolink:NamedThing	cell tip	The region at the end of the longest axis of a cylindrical or elongated cell.	got7fsn_ti	cell end				Note that this term differs from 'cell pole ; GO:0060187' in that it is applicable to the thin ends of elongated cells, such as the ends of axons or dendrites.									cellular_component											owl:Class	
GO:0060187	biolink:NamedThing	cell pole	Either of two different areas at opposite ends of an axis of a cell.	got7fsn_ti					Note that this term differs from 'cell tip ; GO:0051286' in that it is applicable to a broad range of cell shapes including spherical and cuboidal.									cellular_component											owl:Class	
GO:0044300	biolink:NamedThing	cerebellar mossy fiber	An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons a mossy-looking appearance in Golgi stained preparations.	got7fsn_ti	cerebellar mossy fibre						jl	2010-02-05T11:16:40Z				NIF_Subcellular:nlx_subcell_20090209		cellular_component											owl:Class	
GO:0004481	biolink:NamedThing	methylene-fatty-acyl-phospholipid synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid.	got7fsn_ti	S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating)|unsaturated-phospholipid methyltransferase activity|cyclopropane synthetase activity											EC:2.1.1.16|MetaCyc:2.1.1.16-RXN|RHEA:17549		molecular_function											owl:Class	
GO:0007059	biolink:NamedThing	chromosome segregation	The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.	got7fsn_ti	chromosome transmission|chromosome division											Wikipedia:Chromosome_segregation		biological_process											owl:Class	
GO:0015325	biolink:NamedThing	acetyl-CoA:CoA antiporter activity	Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out).	got7fsn_ti														molecular_function											owl:Class	
GO:0008521	biolink:NamedThing	acetyl-CoA transmembrane transporter activity	Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.	got7fsn_ti	acetyl-CoA transporter activity											Reactome:R-HSA-5649742|Reactome:R-HSA-727759		molecular_function											owl:Class	
GO:0042722	biolink:NamedThing	alpha-beta T cell activation by superantigen	The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region.	got7fsn_ti	alpha-beta T-lymphocyte activation by superantigen|alpha-beta T lymphocyte activation by superantigen|alpha-beta T-cell activation by superantigen													biological_process											owl:Class	
GO:0046631	biolink:NamedThing	alpha-beta T cell activation	The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti	alpha-beta T-cell activation|alpha-beta T lymphocyte activation|alpha-beta T-lymphocyte activation													biological_process											owl:Class	
GO:0048393	biolink:NamedThing	intermediate mesodermal cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell.	got7fsn_ti	intermediate mesoderm cell fate commitment													biological_process											owl:Class	
GO:0015054	biolink:NamedThing	gastrin receptor activity	Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity.	got7fsn_ti	cholecystokinin-B receptor activity													molecular_function											owl:Class	
GO:0034207	biolink:NamedThing	steroid acetylation	The addition of an acetyl group to a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti														biological_process											owl:Class	
GO:1990192	biolink:NamedThing	collecting lymphatic vessel constriction	A decrease in the diameter of collecting lymphatic vessels.	got7fsn_ti	lymphatic vessel myogenic constriction						sl	2013-09-12T14:46:05Z						biological_process											owl:Class	
GO:1990186	biolink:NamedThing	regulation of lymphatic vessel size	Any process that modulates the size of lymphatic vessels.	got7fsn_ti	regulation of collecting lymphatic vessel size						sl	2013-09-11T15:41:16Z						biological_process											owl:Class	
GO:0016028	biolink:NamedThing	rhabdomere	The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction.	got7fsn_ti														cellular_component											owl:Class	
GO:0048475	biolink:NamedThing	coated membrane	A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes.	got7fsn_ti														cellular_component											owl:Class	
GO:0034628	biolink:NamedThing	'de novo' NAD biosynthetic process from aspartate	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.	got7fsn_ti	de novo NAD biosynthetic process from aspartate													biological_process											owl:Class	
GO:0034627	biolink:NamedThing	'de novo' NAD biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.	got7fsn_ti	de novo NAD biosynthetic process													biological_process											owl:Class	
GO:0018031	biolink:NamedThing	peptidyl-lysine N6-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.	got7fsn_ti												EC:2.3.1.-		molecular_function											owl:Class	
GO:0018006	biolink:NamedThing	N-terminal protein amino acid glucuronylation	The glucuronylation of the N-terminal amino acid of proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0050659	biolink:NamedThing	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.	got7fsn_ti	GalNAc4S-6ST|3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity|N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity				Consider instead annotating to the individual reactions: 'chondroitin 6-sulfotransferase activity ; GO:0008459' and 'dermatan 6-sulfotransferase activity ; GO:0036443'.							KEGG_REACTION:R02181|Reactome:R-HSA-2018659|MetaCyc:RXN-7954|MetaCyc:RXN-7953|EC:2.8.2.33|KEGG_REACTION:R07288		molecular_function											owl:Class	
GO:0031748	biolink:NamedThing	D1 dopamine receptor binding	Binding to a D1 dopamine receptor.	got7fsn_ti	D1A dopamine receptor binding|D1 dopamine receptor ligand													molecular_function											owl:Class	
GO:0016907	biolink:NamedThing	G protein-coupled acetylcholine receptor activity	Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	metabotropic acetylcholine receptor activity|G protein coupled acetylcholine receptor activity|muscarinic acetylcholine receptor activity|acetylcholine receptor activity, G-protein coupled|G-protein coupled acetylcholine receptor activity										GO:0004981			molecular_function											owl:Class	
GO:0015464	biolink:NamedThing	acetylcholine receptor activity	Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti					For nicotinic acetylcholine receptors that act as ion channels, instead use 'acetylcholine-gated cation channel activity ; GO:0022848'.									molecular_function											owl:Class	
GO:0033788	biolink:NamedThing	leucoanthocyanidin reductase activity	Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.	got7fsn_ti	(2R,3S)-catechin:NADP+ 4-oxidoreductase activity|leucocyanidin reductase activity											RHEA:10616|EC:1.17.1.3|MetaCyc:RXN-1484		molecular_function											owl:Class	
GO:0106240	biolink:NamedThing	labd-13Z-ene-9,15,16-triol synthase activity	Catalysis of the reaction:O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							hjd	2019-12-19T17:43:00Z				RHEA:62192		molecular_function											owl:Class	
GO:0004051	biolink:NamedThing	arachidonate 5-lipoxygenase activity	Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.	got7fsn_ti	C-5-lipoxygenase activity|arachidonic acid 5-lipoxygenase activity|arachidonate:oxygen 5-oxidoreductase activity|leukotriene-A(4) synthase activity|5Delta-lipoxygenase activity|arachidonic 5-lipoxygenase activity|leukotriene A4 synthase|5-lipoxygenase activity|5-delta-lipoxygenase activity|delta5-lipoxygenase activity|leukotriene-A4 synthase activity|delta(5)-lipoxygenase activity|LTA synthase activity											Reactome:R-HSA-9018863|Reactome:R-HSA-9026405|Reactome:R-HSA-9018894|Reactome:R-HSA-9020264|Reactome:R-HSA-9020251|Reactome:R-HSA-9020282|Reactome:R-HSA-9025999|Reactome:R-HSA-9020278|RHEA:32307|Reactome:R-HSA-266051|Reactome:R-HSA-9027624|MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN|Reactome:R-HSA-9025996|Reactome:R-HSA-9020256|Reactome:R-HSA-9025995|Reactome:R-HSA-265296|Reactome:R-HSA-9026005|Reactome:R-HSA-9018859|Reactome:R-HSA-9027628|Reactome:R-HSA-9018858|Reactome:R-HSA-9020259|Reactome:R-HSA-9020277|EC:1.13.11.34|Reactome:R-HSA-9024997|Reactome:R-HSA-9027633|Reactome:R-HSA-9020255		molecular_function											owl:Class	
GO:0050159	biolink:NamedThing	orsellinate decarboxylase activity	Catalysis of the reaction: o-orsellinate + H(+) = CO(2) + orcinol.	got7fsn_ti	orsellinate carboxy-lyase (orcinol-forming)|orsellinate carboxy-lyase activity											MetaCyc:ORSELLINATE-DECARBOXYLASE-RXN|KEGG_REACTION:R02831|RHEA:16733|EC:4.1.1.58		molecular_function											owl:Class	
GO:0072094	biolink:NamedThing	metanephric renal vesicle induction	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.	got7fsn_ti	positive regulation of metanephros formation						mah	2010-02-10T01:23:20Z						biological_process											owl:Class	
GO:0072216	biolink:NamedThing	positive regulation of metanephros development	Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti							mah	2010-03-18T01:40:12Z						biological_process											owl:Class	
GO:0016071	biolink:NamedThing	mRNA metabolic process	The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.	got7fsn_ti	mRNA metabolism													biological_process											owl:Class	
GO:0036009	biolink:NamedThing	protein-glutamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.	got7fsn_ti							bf	2011-10-03T02:27:05Z				Reactome:R-HSA-6800138		molecular_function											owl:Class	
GO:0015834	biolink:NamedThing	peptidoglycan-associated peptide transport	The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.	got7fsn_ti	muropeptide transport|murein peptide transport|peptidoglycan peptide transport													biological_process											owl:Class	
GO:0015833	biolink:NamedThing	peptide transport	The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0016824	biolink:NamedThing	hydrolase activity, acting on acid halide bonds	Catalysis of the hydrolysis of any acid halide bond.	got7fsn_ti												EC:3.8.-.-		molecular_function											owl:Class	
GO:0045814	biolink:NamedThing	negative regulation of gene expression, epigenetic	Any epigenetic process that stops, prevents or reduces the rate of gene expression.	got7fsn_ti	downregulation of gene expression, epigenetic|down-regulation of gene expression, epigenetic|down regulation of gene expression, epigenetic|inhibition of gene expression, epigenetic													biological_process											owl:Class	
GO:0022804	biolink:NamedThing	active transmembrane transporter activity	Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.	got7fsn_ti	pump activity|carrier activity|permease activity|active carrier activity													molecular_function											owl:Class	
GO:0050144	biolink:NamedThing	nucleoside deoxyribosyltransferase activity	Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.	got7fsn_ti	nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase activity|trans-deoxyribosylase activity|nucleoside deoxyribosyltransferase II [purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyltransferase]|nucleoside trans-N-deoxyribosylase activity|deoxyribose transferase activity|trans-N-deoxyribosylase activity|purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl transferase activity|trans-N-glycosidase activity|nucleoside deoxyribosyltransferase I (purine nucleoside:purine deoxyribosyltransferase: strictly specific for transfer between purine bases)											MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN|EC:2.4.2.6		molecular_function											owl:Class	
GO:0010180	biolink:NamedThing	thioglucosidase binding	Binding to a thioglucosidase enzyme.	got7fsn_ti	myrosinase binding													molecular_function											owl:Class	
GO:0120026	biolink:NamedThing	host cell uropod	A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.	got7fsn_ti	host cell uropodium						krc	2017-03-22T21:33:31Z						cellular_component											owl:Class	
GO:0034842	biolink:NamedThing	thiophene-2-carboxylate-CoA ligase activity	Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi.	got7fsn_ti												UM-BBD_reactionID:r1234		molecular_function											owl:Class	
GO:0008235	biolink:NamedThing	metalloexopeptidase activity	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	got7fsn_ti														molecular_function											owl:Class	
GO:0039724	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E).	got7fsn_ti	suppression by virus of host IKBKE activity|inhibition of host IKBKE by virus	https://github.com/geneontology/go-ontology/issues/21985					bf	2014-01-06T12:15:03Z						biological_process											owl:Class	
GO:0039537	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. This is a mechanism by which the virus evades the host innate immune response.	got7fsn_ti	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signalling pathway|suppression by virus of host RIG-I/MDA5 signaling pathway|suppression by virus of host RIG-like receptor signaling pathway|suppression by virus of host RIG-like helicase signaling pathway|suppression by virus of host cytoplasmic pattern recognition receptor signaling pathway in response to virus|suppression by virus of host RIG-I-like receptor (RLR) signaling pathway|suppression by virus of host RLR signaling pathway						bf	2012-01-03T11:47:05Z						biological_process											owl:Class	
GO:0050607	biolink:NamedThing	mycothiol-dependent formaldehyde dehydrogenase activity	Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+.	got7fsn_ti	NAD/factor-dependent formaldehyde dehydrogenase activity|formaldehyde:NAD+ oxidoreductase (mycothiol-formylating)											EC:1.1.1.306|MetaCyc:1.2.1.66-RXN|RHEA:28502		molecular_function											owl:Class	
GO:1902362	biolink:NamedThing	melanocyte apoptotic process	Any apoptotic process in a melanocyte, the main structural component of the epidermis.	got7fsn_ti	melanophore apoptosis|melanophore apoptotic process|melanocyte apoptosis						pr	2013-08-15T16:35:45Z						biological_process											owl:Class	
GO:0044686	biolink:NamedThing	cysteate synthase activity	Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-.	got7fsn_ti							jl	2012-08-15T14:16:05Z				RHEA:26486|MetaCyc:RXN-11108|EC:2.5.1.76		molecular_function											owl:Class	
GO:0036090	biolink:NamedThing	cleavage furrow ingression	Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.	got7fsn_ti	cleavage furrow contraction				Consider also annotating to 'contractile ring contraction involved in cell cycle cytokinesis ; GO:0000916'.		bf	2012-01-10T02:46:05Z						biological_process											owl:Class	
GO:0099024	biolink:NamedThing	plasma membrane invagination	An infolding of the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0072375	biolink:NamedThing	medium-term memory	The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).	got7fsn_ti	MTM|middle-term memory						mah	2010-11-22T11:26:54Z						biological_process											owl:Class	
GO:0007613	biolink:NamedThing	memory	The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).	got7fsn_ti												Wikipedia:Memory		biological_process											owl:Class	
GO:0030583	biolink:NamedThing	myxococcal fruiting body development	The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure.	got7fsn_ti	fruiting body development in response to starvation|fruiting body development in cellular response to starvation				For example, as seen in myxobacterium.  It is not intended to describe fruiting body development as is Dictyostelium.						GO:0055084			biological_process											owl:Class	
GO:0043828	biolink:NamedThing	tRNA 2-selenouridine synthase activity	Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA).	got7fsn_ti												RHEA:42716|MetaCyc:RXN0-2281|EC:2.9.1.3		molecular_function											owl:Class	
GO:0018357	biolink:NamedThing	protein-phycourobilin linkage via phycourobilin-bis-L-cysteine	The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine.	got7fsn_ti											GO:0018383	RESID:AA0260		biological_process											owl:Class	
GO:0017010	biolink:NamedThing	protein-phycourobilin linkage	The linkage of the chromophore phycourobilin to phycoerythrins.	got7fsn_ti												RESID:AA0260		biological_process											owl:Class	
GO:0047478	biolink:NamedThing	aspartate-ammonia ligase (ADP-forming) activity	Catalysis of the reaction: L-aspartate + ATP + NH(4)(+) = L-asparagine + ADP + 2 H(+) + phosphate.	got7fsn_ti	asparagine synthetase (adenosine diphosphate-forming)|asparagine synthetase (ADP-forming) activity|L-aspartate:ammonia ligase (ADP-forming)											MetaCyc:6.3.1.4-RXN|EC:6.3.1.4|RHEA:14197|KEGG_REACTION:R00482		molecular_function											owl:Class	
GO:0061754	biolink:NamedThing	negative regulation of circulating fibrinogen levels	Any process that reduces the quantity of fibrinogen circulating in the bloodstream.	got7fsn_ti							dph	2016-02-29T16:19:09Z						biological_process											owl:Class	
GO:0098529	biolink:NamedThing	neuromuscular junction development, skeletal muscle fiber	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber.	got7fsn_ti														biological_process											owl:Class	
GO:0007528	biolink:NamedThing	neuromuscular junction development	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.	got7fsn_ti	neuromuscular junction organization|neuromuscular junction stability|NMJ stability													biological_process											owl:Class	
GO:0042467	biolink:NamedThing	orthokinesis	The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased.	got7fsn_ti														biological_process											owl:Class	
GO:0004335	biolink:NamedThing	galactokinase activity	Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+).	got7fsn_ti	ATP:D-galactose 1-phosphotransferase activity|galactokinase (phosphorylating)|ATP:D-galactose-1-phosphotransferase activity											KEGG_REACTION:R01092|MetaCyc:GALACTOKIN-RXN|EC:2.7.1.6|RHEA:13553|Reactome:R-HSA-70355|Reactome:R-HSA-5610026		molecular_function											owl:Class	
GO:0048723	biolink:NamedThing	clypeus development	The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head.	got7fsn_ti														biological_process											owl:Class	
GO:0005590	biolink:NamedThing	collagen type VII trimer	A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin.	got7fsn_ti														cellular_component											owl:Class	
GO:0030934	biolink:NamedThing	anchoring collagen complex	Any collagen complex which links one collagen assembly, such as a collagen fibril or sheet, to other structures.	got7fsn_ti	connecting collagen|linking collagen													cellular_component											owl:Class	
GO:0018152	biolink:NamedThing	peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine	The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link.	got7fsn_ti												RESID:AA0270		biological_process											owl:Class	
GO:0018151	biolink:NamedThing	peptide cross-linking via L-histidyl-L-tyrosine	The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link.	got7fsn_ti														biological_process											owl:Class	
GO:0042208	biolink:NamedThing	propylene catabolic process	The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining.	got7fsn_ti	propylene catabolism|propylene breakdown|propylene degradation											UM-BBD_pathwayID:pro		biological_process											owl:Class	
GO:0047707	biolink:NamedThing	biotin-CoA ligase activity	Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA.	got7fsn_ti	biotinyl-CoA synthetase activity|biotin CoA synthetase activity|biotin:CoA ligase (AMP-forming)|biotinyl coenzyme A synthetase activity											EC:6.2.1.11|MetaCyc:BIOTIN--COA-LIGASE-RXN|RHEA:19681		molecular_function											owl:Class	
GO:0102818	biolink:NamedThing	lycopene cleavage oxygenase activity	Catalysis of the reaction: lycopene + 2 O2 <=> 2 sulcatone + bixin aldehyde.	got7fsn_ti												MetaCyc:RXN-8236		molecular_function											owl:Class	
GO:0102871	biolink:NamedThing	1-16:0-2-18:1-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-16:0-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-palmitoyl-2-linoleoyl-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8360|EC:1.14.19.22		molecular_function											owl:Class	
GO:0006699	biolink:NamedThing	bile acid biosynthetic process	The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.	got7fsn_ti	bile acid anabolism|bile acid biosynthesis|bile acid formation|bile acid synthesis													biological_process											owl:Class	
GO:0008206	biolink:NamedThing	bile acid metabolic process	The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.	got7fsn_ti	bile acid metabolism													biological_process											owl:Class	
GO:0010648	biolink:NamedThing	negative regulation of cell communication	Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti														biological_process											owl:Class	
GO:0080007	biolink:NamedThing	S-nitrosoglutathione reductase activity	Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+.	got7fsn_ti												MetaCyc:RXN-10742		molecular_function											owl:Class	
GO:0071475	biolink:NamedThing	cellular hyperosmotic salinity response	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti	cellular response to hyperosmotic salt stress						mah	2009-12-18T11:52:06Z						biological_process											owl:Class	
GO:0071474	biolink:NamedThing	cellular hyperosmotic response	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.	got7fsn_ti	cellular HOG response|cellular hypertonic response|cellular response to hypertonicity						mah	2009-12-18T11:51:36Z						biological_process											owl:Class	
GO:0090655	biolink:NamedThing	double-stranded/single-stranded junction telomeric DNA binding	Binding to a junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang.	got7fsn_ti							tb	2015-07-02T11:33:39Z						molecular_function											owl:Class	
GO:0042162	biolink:NamedThing	telomeric DNA binding	Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.	got7fsn_ti	telomere binding|telomeric repeat binding													molecular_function											owl:Class	
GO:0051755	biolink:NamedThing	meiotic sister chromatid arm separation	The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0001967	biolink:NamedThing	suckling behavior	Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.	got7fsn_ti	nursing behavior													biological_process											owl:Class	
GO:0007631	biolink:NamedThing	feeding behavior	Behavior associated with the intake of food.	got7fsn_ti	injection of substance into other organism during feeding on blood of other organism|feeding from xylem of other organism|behavioural response to food|feeding from plant phloem|feeding from phloem of other organism|feeding behaviour|taking of blood meal|feeding on blood of other organism|behavioral response to food|hematophagy|feeding from tissue of other organism|eating|feeding from vascular tissue of another organism|feeding on or from other organism|feeding on plant sap	https://github.com/geneontology/go-ontology/issues/18547			See also the biological process term 'behavior ; GO:0007610'.		jl	2011-10-27T03:53:33Z			GO:0044369|GO:0044367|GO:0044366|GO:0044370|GO:0044371|GO:0044368|GO:0044372	Wikipedia:List_of_feeding_behaviours		biological_process											owl:Class	
GO:0005652	biolink:NamedThing	nuclear lamina	The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.	got7fsn_ti												NIF_Subcellular:sao1455996588|Wikipedia:Nuclear_lamina		cellular_component											owl:Class	
GO:0006238	biolink:NamedThing	CMP salvage	Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis.	got7fsn_ti	cytidine monophosphate salvage													biological_process											owl:Class	
GO:0009224	biolink:NamedThing	CMP biosynthetic process	The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate.	got7fsn_ti	CMP formation|CMP anabolism|CMP synthesis|CMP biosynthesis													biological_process											owl:Class	
GO:0043667	biolink:NamedThing	pollen wall	The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine.	got7fsn_ti	microspore wall													cellular_component											owl:Class	
GO:0097608	biolink:NamedThing	transverse flagellum	A motile cilium found in dinoflagellates. It coils around the cell and provides the forward thrust for motility. It is often contained in a furrow called the cingulum, and emerges from a flagellar pore located in the cingulum.	got7fsn_ti	transverse cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent. In this case community usage refers to 'flagellum' rather than 'cilium', hence the primary term name, but the cilium parentage is deliberate.		pr	2014-06-09T11:14:37Z						cellular_component											owl:Class	
GO:0002194	biolink:NamedThing	hepatocyte cell migration	The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes.	got7fsn_ti							hjd	2011-08-30T04:27:39Z						biological_process											owl:Class	
GO:1900571	biolink:NamedThing	diorcinol catabolic process	The chemical reactions and pathways resulting in the breakdown of diorcinol.	got7fsn_ti	diorcinol breakdown|diorcinol degradation|diorcinol catabolism						di	2012-05-15T06:35:22Z						biological_process											owl:Class	
GO:0008345	biolink:NamedThing	larval locomotory behavior	Locomotory behavior in a larval (immature) organism.	got7fsn_ti	larval locomotory behaviour				See also the biological process term 'locomotory behavior ; GO:0007626'.									biological_process											owl:Class	
GO:0007626	biolink:NamedThing	locomotory behavior	The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.	got7fsn_ti	locomotory behaviour|locomotion in response to stimulus|behavior via locomotion|locomotory behavioural response to stimulus|locomotory behavioral response to stimulus													biological_process											owl:Class	
GO:0018287	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide	The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron tetrasulphide											RESID:AA0139		biological_process											owl:Class	
GO:0018855	biolink:NamedThing	2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity	Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.	got7fsn_ti												RHEA:33419|UM-BBD_reactionID:r0429|EC:6.2.1.38		molecular_function											owl:Class	
GO:0051631	biolink:NamedThing	regulation of acetylcholine uptake	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.	got7fsn_ti	regulation of acetylcholine import													biological_process											owl:Class	
GO:0044619	biolink:NamedThing	positive regulation of relaxation of uterine smooth muscle in other organism	The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism.	got7fsn_ti							jl	2012-07-04T02:51:26Z						biological_process											owl:Class	
GO:1900721	biolink:NamedThing	positive regulation of uterine smooth muscle relaxation	Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation.	got7fsn_ti	up-regulation of uterine smooth muscle relaxation|positive regulation of smooth muscle relaxation of the uterus|up regulation of smooth muscle relaxation of the uterus|activation of smooth muscle relaxation of the uterus|up-regulation of smooth muscle relaxation of the uterus|up regulation of uterine smooth muscle relaxation|upregulation of uterine smooth muscle relaxation|activation of uterine smooth muscle relaxation|upregulation of smooth muscle relaxation of the uterus						jl	2012-05-24T03:12:57Z						biological_process											owl:Class	
GO:0031523	biolink:NamedThing	Myb complex	A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression.	got7fsn_ti	Myeloblastosis proto-oncogene protein complex													cellular_component											owl:Class	
GO:0002029	biolink:NamedThing	desensitization of G protein-coupled receptor signaling pathway	The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway.	got7fsn_ti	desensitization of G-protein coupled receptor protein signaling pathway|desensitisation of G-protein coupled receptor protein signalling pathway													biological_process											owl:Class	
GO:0045744	biolink:NamedThing	negative regulation of G protein-coupled receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.	got7fsn_ti	negative regulation of G-protein coupled receptor protein signalling pathway|downregulation of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein-coupled receptor protein signalling pathway|inhibition of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein coupled receptor protein signaling pathway|negative regulation of GPCR protein signaling pathway|negative regulation of GPCR protein signalling pathway|down regulation of G-protein coupled receptor protein signaling pathway|negative regulation of G protein coupled receptor protein signaling pathway|down-regulation of G-protein coupled receptor protein signaling pathway|negative regulation of G protein coupled receptor protein signalling pathway													biological_process											owl:Class	
GO:0019758	biolink:NamedThing	glycosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.	got7fsn_ti	glycosinolate biosynthesis|glycosinolate synthesis|glycosinolate formation|glycosinolate anabolism													biological_process											owl:Class	
GO:1990697	biolink:NamedThing	protein depalmitoleylation	The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein.	got7fsn_ti							sp	2015-03-13T08:55:31Z						biological_process											owl:Class	
GO:0042159	biolink:NamedThing	lipoprotein catabolic process	The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.	got7fsn_ti	lipoprotein degradation|lipoprotein breakdown|lipoprotein catabolism													biological_process											owl:Class	
GO:0102746	biolink:NamedThing	tetrahydrogeranylgeranyl-PP reductase activity	Catalysis of the reaction: H+ + tetrahydrogeranylgeranyl-PP + NADPH = (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + NADP.	got7fsn_ti												MetaCyc:RXN-7660		molecular_function											owl:Class	
GO:0010088	biolink:NamedThing	phloem development	The formation of the principal food-conducting tissue of a vascular plant.	got7fsn_ti	phloem histogenesis													biological_process											owl:Class	
GO:0006562	biolink:NamedThing	proline catabolic process	The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.	got7fsn_ti	proline breakdown|proline degradation|proline catabolism													biological_process											owl:Class	
GO:0070826	biolink:NamedThing	paraferritin complex	A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.	got7fsn_ti							mah	2009-07-23T03:05:08Z						cellular_component											owl:Class	
GO:0030727	biolink:NamedThing	germarium-derived female germ-line cyst formation	Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	germarium-derived female germline cyst formation													biological_process											owl:Class	
GO:0048135	biolink:NamedThing	female germ-line cyst formation	Formation of a group of interconnected cells derived from a single female gonial founder cell.	got7fsn_ti	female germline cyst formation													biological_process											owl:Class	
GO:0003272	biolink:NamedThing	endocardial cushion formation	The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	got7fsn_ti							dph	2009-10-20T08:53:19Z						biological_process											owl:Class	
GO:0044623	biolink:NamedThing	positive regulation of cell migration in other organism	Any process that activates or increases the frequency, rate or extent of cell migration in a second organism.	got7fsn_ti							jl	2012-07-04T04:44:59Z						biological_process											owl:Class	
GO:0043564	biolink:NamedThing	Ku70:Ku80 complex	Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.	got7fsn_ti	Ku70:Ku80 heterodimer													cellular_component											owl:Class	
GO:0034015	biolink:NamedThing	L-ribulose-5-phosphate 3-epimerase activity	Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate.	got7fsn_ti	UlaE|SgaU|L-xylulose 5-phosphate 3-epimerase activity											EC:5.1.3.22|MetaCyc:LXULRU5P-RXN|RHEA:18497		molecular_function											owl:Class	
GO:0005956	biolink:NamedThing	protein kinase CK2 complex	A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein.	got7fsn_ti	casein kinase II complex				Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex.									cellular_component											owl:Class	
GO:0106262	biolink:NamedThing	1-acylglycerophosphoethanolamine O-acyltransferase activity	Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA.	got7fsn_ti							hjd	2020-05-18T15:09:57Z				RHEA:32995		molecular_function											owl:Class	
GO:0045317	biolink:NamedThing	equator specification	The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.	got7fsn_ti														biological_process											owl:Class	
GO:0051965	biolink:NamedThing	positive regulation of synapse assembly	Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.	got7fsn_ti	positive regulation of synaptogenesis|activation of synapse assembly|upregulation of synapse assembly|positive regulation of synapse biogenesis|up-regulation of synapse assembly|up regulation of synapse assembly|stimulation of synapse assembly													biological_process											owl:Class	
GO:0044089	biolink:NamedThing	positive regulation of cellular component biogenesis	Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.	got7fsn_ti														biological_process											owl:Class	
GO:0102724	biolink:NamedThing	UDP-glucose:curcumin monoglucoside glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP.	got7fsn_ti												MetaCyc:RXN-7063		molecular_function											owl:Class	
GO:0046921	biolink:NamedThing	alpha-(1->6)-fucosyltransferase activity	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.	got7fsn_ti	alpha-(1,6)-fucosyltransferase activity|alpha(1,6)-fucosyltransferase activity|alpha-1,6-fucosyltransferase activity													molecular_function											owl:Class	
GO:0008417	biolink:NamedThing	fucosyltransferase activity	Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	got7fsn_ti												Reactome:R-HSA-9033949		molecular_function											owl:Class	
GO:0032801	biolink:NamedThing	receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti	receptor degradation|receptor breakdown|receptor catabolism													biological_process											owl:Class	
GO:0043112	biolink:NamedThing	receptor metabolic process	The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti	receptor metabolism													biological_process											owl:Class	
GO:0075275	biolink:NamedThing	telium development	The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0047105	biolink:NamedThing	4-trimethylammoniobutyraldehyde dehydrogenase activity	Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate.	got7fsn_ti	4-trimethylammoniobutanal:NAD+ 1-oxidoreductase activity|4-N-trimethylaminobutyraldehyde dehydrogenase activity|4-trimethylaminobutyraldehyde dehydrogenase activity											MetaCyc:1.2.1.47-RXN|RHEA:17985|EC:1.2.1.47		molecular_function											owl:Class	
GO:0004827	biolink:NamedThing	proline-tRNA ligase activity	Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).	got7fsn_ti	prolinyl-tRNA ligase activity|proline translase activity|prolyl-s-RNA synthetase activity|prolyl-transferRNA synthetase activity|prolyl-transfer ribonucleic acid synthetase activity|prolyl-tRNA synthetase activity|L-proline:tRNAPro ligase (AMP-forming)|prolyl-transfer ribonucleate synthetase activity											MetaCyc:PROLINE--TRNA-LIGASE-RXN|EC:6.1.1.15|Reactome:R-HSA-380198|Reactome:R-HSA-379865|RHEA:14305		molecular_function											owl:Class	
GO:0004812	biolink:NamedThing	aminoacyl-tRNA ligase activity	Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.	got7fsn_ti	ligase activity, forming aminoacyl-tRNA and related compounds|aminoacyl-tRNA synthetase auxiliary protein activity|aminoacyl-tRNA synthetase activity				Note that the bond resulting from this reaction is a carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2' or 3' hydroxyl of the 3'- terminal adenyl residue of the tRNA.						GO:0017100|GO:0016876	EC:6.1.1.-		molecular_function											owl:Class	
GO:0060827	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern.	got7fsn_ti	regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation|regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation|regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation|regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation						dph	2009-08-11T01:48:52Z						biological_process											owl:Class	
GO:0050176	biolink:NamedThing	phenylalanine N-acetyltransferase activity	Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+).	got7fsn_ti	acetyl-CoA-L-phenylalanine alpha-N-acetyltransferase activity|acetyl-CoA:L-phenylalanine N-acetyltransferase activity											EC:2.3.1.53|KEGG_REACTION:R00693|RHEA:17801|MetaCyc:PHENYLALANINE-N-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:1990196	biolink:NamedThing	MacAB-TolC complex	The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC.	got7fsn_ti	macrolide transporter MacAB-TolC complex						bhm	2013-09-23T11:29:28Z						cellular_component											owl:Class	
GO:1990195	biolink:NamedThing	macrolide transmembrane transporter complex	A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes.	got7fsn_ti	AcrAB-TolC complex|macrolide transporter complex|MacAB-TolC complex|macrolide transporter						bhm	2013-09-23T11:22:26Z						cellular_component											owl:Class	
GO:0052742	biolink:NamedThing	phosphatidylinositol kinase activity	Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate.	got7fsn_ti							ai	2011-09-14T01:21:47Z						molecular_function											owl:Class	
GO:0070096	biolink:NamedThing	mitochondrial outer membrane translocase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.	got7fsn_ti	mitochondrion outer membrane translocase complex assembly|TOM complex assembly													biological_process											owl:Class	
GO:0046230	biolink:NamedThing	2-aminobenzenesulfonate catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.	got7fsn_ti	2-aminobenzenesulfonate catabolism|2-aminobenzenesulfonate degradation|2-aminobenzenesulphonate catabolism|2-aminobenzenesulphonate catabolic process|2-aminobenzenesulfonate breakdown													biological_process											owl:Class	
GO:0009310	biolink:NamedThing	amine catabolic process	The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.	got7fsn_ti	amine catabolism|amine breakdown|amine degradation													biological_process											owl:Class	
GO:0046997	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin.	got7fsn_ti												EC:1.5.8.-		molecular_function											owl:Class	
GO:0000735	biolink:NamedThing	removal of nonhomologous ends	The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.	got7fsn_ti														biological_process											owl:Class	
GO:0000376	biolink:NamedThing	RNA splicing, via transesterification reactions with guanosine as nucleophile	Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.	got7fsn_ti														biological_process											owl:Class	
GO:0000375	biolink:NamedThing	RNA splicing, via transesterification reactions	Splicing of RNA via a series of two transesterification reactions.	got7fsn_ti	spliceosomal catalysis|RNA splicing factor activity, transesterification mechanism|pre-mRNA splicing factor activity				Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism.						GO:0031202|GO:0000385			biological_process											owl:Class	
GO:0043961	biolink:NamedThing	succinyl-CoA:(R)-citramalate CoA-transferase activity	Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.	got7fsn_ti	L-carnitine dehydratase/bile acid-inducible protein F|succinyl-CoA:R-citramalate CoA transferase|succinyl-CoA:(R)-citramalate CoA transferase activity											MetaCyc:RXN-8966|EC:2.8.3.20|RHEA:38279		molecular_function											owl:Class	
GO:0008713	biolink:NamedThing	ADP-heptose-lipopolysaccharide heptosyltransferase activity	Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+.	got7fsn_ti	ADP-heptose:LPS heptosyltransferase activity											RHEA:28538|MetaCyc:RXN0-5061		molecular_function											owl:Class	
GO:0008920	biolink:NamedThing	lipopolysaccharide heptosyltransferase activity	Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+.	got7fsn_ti	LPS heptosyltransferase activity													molecular_function											owl:Class	
GO:0034290	biolink:NamedThing	holin activity	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate.	got7fsn_ti														molecular_function											owl:Class	
GO:0090015	biolink:NamedThing	positive regulation of leaflet formation by auxin mediated signaling pathway	Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin.	got7fsn_ti	positive regulation of leaflet formation by auxin mediated signalling pathway						tb	2009-07-29T11:18:45Z						biological_process											owl:Class	
GO:0009734	biolink:NamedThing	auxin-activated signaling pathway	A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	auxin mediated signalling|auxin signal transduction|auxin mediated signaling pathway|auxin-regulated transcription|auxin signaling													biological_process											owl:Class	
GO:0051652	biolink:NamedThing	maintenance of chromosome location	Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of chromosome localization													biological_process											owl:Class	
GO:0051657	biolink:NamedThing	maintenance of organelle location	Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of organelle localization													biological_process											owl:Class	
GO:0022010	biolink:NamedThing	central nervous system myelination	The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.	got7fsn_ti	myelination in central nervous system													biological_process											owl:Class	
GO:0032291	biolink:NamedThing	axon ensheathment in central nervous system	The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.	got7fsn_ti	ensheathment of axons in central nervous system													biological_process											owl:Class	
GO:0061585	biolink:NamedThing	hypocretin secretion, neurotransmission	The controlled release of a peptide from a cell or a tissue in which the peptide acts as a neurotransmitter.	got7fsn_ti	orexin secretion, neurotransmission						dph	2013-12-26T10:09:37Z						biological_process											owl:Class	
GO:0003872	biolink:NamedThing	6-phosphofructokinase activity	Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.	got7fsn_ti	6-phosphofructokinase reduction|fructose 6-phosphate kinase activity|nucleotide triphosphate-dependent phosphofructokinase activity|phosphohexokinase activity|D-fructose-6-phosphate 1-phosphotransferase activity|phospho-1,6-fructokinase activity|ATP-dependent phosphofructokinase activity|PFK|phosphofructokinase (phosphorylating)|ATP:D-fructose-6-phosphate 1-phosphotransferase activity|phosphofructokinase I activity|6-phosphofructose 1-kinase activity|fructose 6-phosphokinase activity											MetaCyc:6PFRUCTPHOS-RXN|RHEA:16109|Reactome:R-HSA-70467|EC:2.7.1.11		molecular_function											owl:Class	
GO:0008443	biolink:NamedThing	phosphofructokinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0042605	biolink:NamedThing	peptide antigen binding	Binding to an antigen peptide.	got7fsn_ti	exogenous peptide antigen binding|endogenous peptide antigen binding				Note that this term can be used to describe the binding of a peptide to an MHC molecule.						GO:0042607|GO:0042606			molecular_function											owl:Class	
GO:0003823	biolink:NamedThing	antigen binding	Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.	got7fsn_ti	B cell receptor activity|immunoglobulin|antibody|opsonin activity													molecular_function											owl:Class	
GO:0047290	biolink:NamedThing	(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP.	got7fsn_ti	(alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity|SIAT7|CMP-N-acetylneuraminate:(alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3)-N-acetyl-D-galactosaminide alpha-2,6-N-acetylneuraminyl-transferase activity|(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity|sialyltransferase 3C activity|alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity|ST6GALNAC activity|cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase activity|sialyltransferase 7D activity|NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity											Reactome:R-HSA-981809|MetaCyc:2.4.99.7-RXN|EC:2.4.99.7|RHEA:53896|KEGG_REACTION:R04635		molecular_function											owl:Class	
GO:0008828	biolink:NamedThing	dATP pyrophosphohydrolase activity	Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate.	got7fsn_ti	2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity|2-hydroxy-ATP pyrophosphatase activity|2-hydroxy-(d)ATP pyrophosphatase activity|2-hydroxy-adenosine triphosphate pyrophosphatase activity	https://github.com/geneontology/go-ontology/issues/20656					jl	2012-10-18T13:22:38Z			GO:0044713|GO:0044714	EC:3.6.1.56|Reactome:R-HSA-2395818|Reactome:R-HSA-2395872|MetaCyc:RXN0-384		molecular_function											owl:Class	
GO:0097227	biolink:NamedThing	sperm annulus	The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity.	got7fsn_ti							pr	2012-01-25T01:26:17Z						cellular_component											owl:Class	
GO:0038063	biolink:NamedThing	collagen-activated tyrosine kinase receptor signaling pathway	A series of molecular signals initiated by the binding of collagen to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	collagen-activated RTK signaling pathway|DDR signaling pathway|discoidin domain receptor signaling pathway|collagen-activated tyrosine kinase receptor signalling pathway						bf	2012-01-18T01:43:20Z						biological_process											owl:Class	
GO:0038065	biolink:NamedThing	collagen-activated signaling pathway	A series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	collagen-activated signalling pathway						bf	2012-01-18T01:57:37Z						biological_process											owl:Class	
GO:0000366	biolink:NamedThing	intergenic mRNA trans splicing	The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.	got7fsn_ti	intergenic nuclear mRNA trans splicing													biological_process											owl:Class	
GO:0000365	biolink:NamedThing	mRNA trans splicing, via spliceosome	The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.	got7fsn_ti	nuclear mRNA trans splicing, via U2-type spliceosome|nuclear mRNA trans splicing, via spliceosome													biological_process											owl:Class	
GO:0044489	biolink:NamedThing	negative regulation of voltage-gated sodium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.	got7fsn_ti							jl	2012-02-01T12:21:02Z						biological_process											owl:Class	
GO:0045914	biolink:NamedThing	negative regulation of catecholamine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.	got7fsn_ti	downregulation of catecholamine metabolic process|negative regulation of catecholamine metabolism|inhibition of catecholamine metabolic process|down regulation of catecholamine metabolic process|down-regulation of catecholamine metabolic process													biological_process											owl:Class	
GO:0004117	biolink:NamedThing	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin.	got7fsn_ti												Reactome:R-HSA-111955		molecular_function											owl:Class	
GO:0004114	biolink:NamedThing	3',5'-cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.	got7fsn_ti	3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity|cyclic 3',5'-nucleotide phosphodiesterase activity|3',5'-nucleotide phosphodiesterase activity|nucleoside-3',5-monophosphate phosphodiesterase activity|3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity|3',5'-cyclonucleotide phosphodiesterase activity|3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity|3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity|cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity|cyclic 3',5'-mononucleotide phosphodiesterase activity|cyclic 3',5-nucleotide monophosphate phosphodiesterase activity|nucleoside 3',5'-cyclic phosphate diesterase activity|PDE|3',5' cyclic-nucleotide phosphodiesterase activity|cyclic nucleotide phosphodiesterase activity|cyclic AMP phosphodiesterase activity|cyclic 3',5'-phosphodiesterase activity											RHEA:14653|EC:3.1.4.17|Reactome:R-HSA-162425|MetaCyc:3.1.4.17-RXN		molecular_function											owl:Class	
GO:0019820	biolink:NamedThing	P2 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed.	got7fsn_ti	peroxisome vesicle				Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'.									cellular_component											owl:Class	
GO:0030232	biolink:NamedThing	insulin control element activator complex	Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription.	got7fsn_ti	ICE activator complex													cellular_component											owl:Class	
GO:0051359	biolink:NamedThing	peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine	The formation of the fluorescent protein FP611 chromophore cross-link from the alpha-carboxyl carbon of residue n, a methionine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like fluorescent chromoprotein from the sea anemone Entacmaea quadricolor.	got7fsn_ti	biosynthetic process of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine				See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.							RESID:AA0379		biological_process											owl:Class	
GO:0002459	biolink:NamedThing	adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).	got7fsn_ti	adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains|adaptive immune response based on somatic recombination of VLR built from LRR domains|adaptive immune response in jawless fish													biological_process											owl:Class	
GO:0002250	biolink:NamedThing	adaptive immune response	An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).	got7fsn_ti	immune memory response|acquired immune response											Wikipedia:Adaptive_immune_system		biological_process											owl:Class	
GO:0047920	biolink:NamedThing	geissoschizine dehydrogenase activity	Catalysis of the reaction: geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + H(+) + NADPH.	got7fsn_ti	geissoschizine:NADP+ 4,21-oxidoreductase activity											KEGG_REACTION:R03860|EC:1.3.1.36|RHEA:11376|MetaCyc:GEISSOSCHIZINE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0047085	biolink:NamedThing	hydroxyphenylacetonitrile 2-monooxygenase activity	Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H(+) + NADPH + O(2) = 4-hydroxymandelonitrile + H(2)O + NADP(+).	got7fsn_ti	4-hydroxyphenylacetonitrile hydroxylase activity|4-hydroxyphenylacetonitrile monooxygenase activity|4-hydroxyphenylacetonitrile,NADPH:oxygen oxidoreductase (2-hydroxylating)											RHEA:23740|KEGG_REACTION:R02708|MetaCyc:1.14.13.42-RXN		molecular_function											owl:Class	
GO:0015940	biolink:NamedThing	pantothenate biosynthetic process	The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	got7fsn_ti	pantothenate synthesis|pantothenate biosynthetic process from 2-dehydropantolactone|pantothenate biosynthesis|pantothenate synthesis from valine|vitamin B5 biosynthetic process|pantothenate anabolism|pantothenate biosynthetic process from 2-oxypantoyl lactone|vitamin B5 biosynthesis|pantothenate biosynthesis from valine|pantothenate anabolism from 2-oxypantoyl lactone|pantothenate biosynthesis from 2-oxypantoyl lactone|pantothenate formation from valine|pantothenate anabolism from valine|pantothenate formation from 2-oxypantoyl lactone|pantothenate biosynthetic process from valine|pantothenate synthesis from 2-oxypantoyl lactone|pantothenate formation										GO:0033318|GO:0033317	MetaCyc:PWY-4221|MetaCyc:PANTOSYN-PWY|MetaCyc:PANTO-PWY|MetaCyc:PWY-3961		biological_process											owl:Class	
GO:0030270	biolink:NamedThing	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity	Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran.	got7fsn_ti	FTR|formylmethanofuran-tetrahydromethanopterin formyltransferase activity|formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase activity|formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase activity|N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase activity|formylmethanofuran:tetrahydromethanopterin formyltransferase activity										GO:0018714	RHEA:18061|EC:2.3.1.101|MetaCyc:2.3.1.101-RXN|UM-BBD_reactionID:r0346|KEGG_REACTION:R03390		molecular_function											owl:Class	
GO:0008232	biolink:NamedThing	activator ecdysone receptor complex	A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes.	got7fsn_ti	activator ecdysone receptor holocomplex													cellular_component											owl:Class	
GO:0008230	biolink:NamedThing	ecdysone receptor holocomplex	A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.	got7fsn_ti														cellular_component											owl:Class	
GO:1990019	biolink:NamedThing	protein storage vacuole organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole.	got7fsn_ti							tb	2012-12-20T21:00:09Z						biological_process											owl:Class	
GO:0036202	biolink:NamedThing	ent-cassa-12,15-diene 11-hydroxylase activity	Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O.	got7fsn_ti	ent-cassadiene C11alpha-hydroxylase activity						bf	2012-04-20T02:34:13Z				KEGG_REACTION:R09866|EC:1.14.14.112|RHEA:31967		molecular_function											owl:Class	
GO:0060960	biolink:NamedThing	cardiac neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.	got7fsn_ti	heart neuron fate commitment						dph	2009-09-30T10:23:47Z						biological_process											owl:Class	
GO:0035898	biolink:NamedThing	parathyroid hormone secretion	The regulated release of parathyroid hormone into the circulatory system.	got7fsn_ti	PTH secretion|parathormone secretion|parathyrin secretion						bf	2011-06-22T09:28:54Z						biological_process											owl:Class	
GO:0060986	biolink:NamedThing	endocrine hormone secretion	The regulated release of a hormone into the circulatory system.	got7fsn_ti							dph	2010-01-11T09:03:48Z						biological_process											owl:Class	
GO:0035313	biolink:NamedThing	wound healing, spreading of epidermal cells	The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.	got7fsn_ti														biological_process											owl:Class	
GO:0044319	biolink:NamedThing	wound healing, spreading of cells	The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.	got7fsn_ti	cell migration involved in wound healing epiboly						jl	2010-07-14T02:10:01Z						biological_process											owl:Class	
GO:0034470	biolink:NamedThing	ncRNA processing	Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0032456	biolink:NamedThing	endocytic recycling	The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.	got7fsn_ti	retrograde transport of endocytic vesicles|retrograde transport, endosome to plasma membrane	https://github.com/geneontology/go-ontology/issues/20747					sp	2013-06-18T10:52:50Z			GO:1990126			biological_process											owl:Class	
GO:0016197	biolink:NamedThing	endosomal transport	The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.	got7fsn_ti	endosome transport|endosome localization|endosome localisation										GO:0032439			biological_process											owl:Class	
GO:0033130	biolink:NamedThing	acetylcholine receptor binding	Binding to an acetylcholine receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0045198	biolink:NamedThing	establishment of epithelial cell apical/basal polarity	The specification and formation of the apicobasal polarity of an epithelial cell.	got7fsn_ti														biological_process											owl:Class	
GO:0030859	biolink:NamedThing	polarized epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.	got7fsn_ti														biological_process											owl:Class	
GO:0043989	biolink:NamedThing	histone H4-S1 phosphorylation	The modification of histone H4 by the addition of an phosphate group to a serine residue at position 1 of the histone.	got7fsn_ti	histone H4S1 phosphorylation|histone H4 phosphorylation at S1													biological_process											owl:Class	
GO:0035404	biolink:NamedThing	histone-serine phosphorylation	The modification of histones by addition of a phosphate group to a serine residue.	got7fsn_ti	histone serine phosphorylation						bf	2010-03-24T10:08:25Z						biological_process											owl:Class	
GO:0070479	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay	The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.	got7fsn_ti	5'-3' NMD|5'-3' nonsense-mediated mRNA decay|5'-3' nonsense-mediated decay|nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay|nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay|nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay													biological_process											owl:Class	
GO:0070480	biolink:NamedThing	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay.	got7fsn_ti	exonucleolytic nuclear-transcribed mRNA degradation involved in deadenylation-independent decay|exonucleolytic nuclear-transcribed mRNA breakdown involved in deadenylation-independent decay|exonucleolytic nuclear-transcribed mRNA catabolism involved in deadenylation-independent decay													biological_process											owl:Class	
GO:0031807	biolink:NamedThing	H1 histamine receptor binding	Binding to a H1 histamine receptor.	got7fsn_ti	H1 histamine receptor ligand													molecular_function											owl:Class	
GO:0031806	biolink:NamedThing	G protein-coupled histamine receptor binding	Binding to a G protein-coupled (metabotropic) histamine receptor.	got7fsn_ti	G-protein coupled histamine receptor binding|metabotropic histamine receptor ligand|metabotropic histamine receptor binding													molecular_function											owl:Class	
GO:0070571	biolink:NamedThing	negative regulation of neuron projection regeneration	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.	got7fsn_ti	growth cone collapse						mah	2009-04-15T01:43:19Z						biological_process											owl:Class	
GO:0010977	biolink:NamedThing	negative regulation of neuron projection development	Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	got7fsn_ti	negative regulation of neurite biosynthesis|negative regulation of neurite development|negative regulation of neurite growth|growth cone collapse|negative regulation of neurite formation						tb	2009-06-01T10:47:42Z						biological_process											owl:Class	
GO:0048531	biolink:NamedThing	beta-1,3-galactosyltransferase activity	Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage.	got7fsn_ti														molecular_function											owl:Class	
GO:0008378	biolink:NamedThing	galactosyltransferase activity	Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	got7fsn_ti												Reactome:R-HSA-1964501		molecular_function											owl:Class	
GO:0080146	biolink:NamedThing	L-cysteine desulfhydrase activity	Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+.	got7fsn_ti							dhl	2010-01-27T04:50:43Z				Reactome:R-HSA-1614591|MetaCyc:LCYSDESULF-RXN|Reactome:R-HSA-1614614|RHEA:24931|EC:4.4.1.1		molecular_function											owl:Class	
GO:0038133	biolink:NamedThing	ERBB2-ERBB3 signaling pathway	A series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission.	got7fsn_ti	ERBB2-ERBB3 signalling pathway|HER2-HER3 signaling pathway						bf	2012-03-30T11:10:44Z						biological_process											owl:Class	
GO:0038129	biolink:NamedThing	ERBB3 signaling pathway	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission.	got7fsn_ti	HER3 signaling pathway|receptor tyrosine-protein kinase erbB-3 signaling pathway|ERBB3 signalling pathway						bf	2012-03-30T10:42:28Z						biological_process											owl:Class	
GO:0070081	biolink:NamedThing	clathrin-sculpted monoamine transport vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.	got7fsn_ti	clathrin sculpted monoamine transport vesicle|clathrin sculpted monoamine constitutive secretory pathway transport vesicle													cellular_component											owl:Class	
GO:0060198	biolink:NamedThing	clathrin-sculpted vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release.	got7fsn_ti	clathrin sculpted vesicle													cellular_component											owl:Class	
GO:0090727	biolink:NamedThing	positive regulation of brood size	Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.	got7fsn_ti							tb	2016-12-19T15:07:32Z						biological_process											owl:Class	
GO:0060378	biolink:NamedThing	regulation of brood size	Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.	got7fsn_ti														biological_process											owl:Class	
GO:0000754	biolink:NamedThing	adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion	In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae.	got7fsn_ti	adaptation to pheromone during conjugation with cellular fusion|desensitization to pheromone during conjugation with cellular fusion|adaptation of signalling pathway by response to pheromone involved in conjugation with cellular fusion										GO:0030453|GO:0007331			biological_process											owl:Class	
GO:0102650	biolink:NamedThing	cyclo-acetoacetyl-L-tryptophan synthetase activity	Catalysis of the reaction: acetoacetyl-ACP + L-tryptophan  + ATP <=> cyclo-acetoacetyl-L-tryptophan + AMP + diphosphoric acid + 2 H+ + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-15811		molecular_function											owl:Class	
GO:0032288	biolink:NamedThing	myelin assembly	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.	got7fsn_ti	myelin formation													biological_process											owl:Class	
GO:0010927	biolink:NamedThing	cellular component assembly involved in morphogenesis	The cellular component assembly that is part of the initial shaping of the component during its developmental progression.	got7fsn_ti														biological_process											owl:Class	
GO:0009846	biolink:NamedThing	pollen germination	The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.	got7fsn_ti														biological_process											owl:Class	
GO:0070211	biolink:NamedThing	Snt2C complex	A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.	got7fsn_ti														cellular_component											owl:Class	
GO:0016360	biolink:NamedThing	sensory organ precursor cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	sense organ precursor cell fate determination													biological_process											owl:Class	
GO:0035176	biolink:NamedThing	social behavior	Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.	got7fsn_ti	social behaviour|cooperative behavior				Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior.							Wikipedia:Social_behavior		biological_process											owl:Class	
GO:0098933	biolink:NamedThing	disruption by symbiont of host cell envelope	The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0052008	biolink:NamedThing	disruption by symbiont of host cellular component	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism of host structural constituent by organism|catabolism of host cellular component by organism|disassembly by symbiont of host cellular component|degradation of host cellular component by organism|disassembly by organism of host cellular component													biological_process											owl:Class	
GO:0106258	biolink:NamedThing	L-serine-phosphatidylcholine phosphatidyltransferase activity	Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline.	got7fsn_ti							hjd	2020-04-21T17:31:56Z				RHEA:45088		molecular_function											owl:Class	
GO:0005943	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class IA	A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.	got7fsn_ti	class IA PI3K complex|phosphoinositide 3-kinase complex, class IA|1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex|1-phosphatidylinositol-4-phosphate kinase, class IA complex										GO:0035030			cellular_component											owl:Class	
GO:0097651	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class I	A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast.	got7fsn_ti	class I phosphatidylinositol 3-kinase complex|class I PI3K complex						pr	2014-09-16T11:19:58Z						cellular_component											owl:Class	
GO:0061411	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to cold	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.	got7fsn_ti							dph	2012-01-12T12:31:33Z						biological_process											owl:Class	
GO:0061244	biolink:NamedThing	mesonephric S-shaped body morphogenesis	The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.	got7fsn_ti							dph	2010-08-19T03:23:55Z						biological_process											owl:Class	
GO:0072050	biolink:NamedThing	S-shaped body morphogenesis	The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.	got7fsn_ti							mah	2010-01-25T03:45:19Z						biological_process											owl:Class	
GO:1900606	biolink:NamedThing	tensidol B metabolic process	The chemical reactions and pathways involving tensidol B.	got7fsn_ti	tensidol B metabolism						di	2012-05-15T06:58:21Z						biological_process											owl:Class	
GO:0007307	biolink:NamedThing	eggshell chorion gene amplification	Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster.	got7fsn_ti														biological_process											owl:Class	
GO:0006486	biolink:NamedThing	protein glycosylation	A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.	got7fsn_ti	protein amino acid glycosylation|protein-carbohydrate complex assembly										GO:0065006			biological_process											owl:Class	
GO:0043413	biolink:NamedThing	macromolecule glycosylation	The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.	got7fsn_ti														biological_process											owl:Class	
GO:0044538	biolink:NamedThing	host cell periphery	The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell.	got7fsn_ti							jl	2012-03-21T03:26:33Z						cellular_component											owl:Class	
GO:0097267	biolink:NamedThing	omega-hydroxylase P450 pathway	The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.	got7fsn_ti	P450 omega-hydroxylase pathway						pr	2012-03-15T12:58:15Z						biological_process											owl:Class	
GO:0075226	biolink:NamedThing	encysted zoospore germination	The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appressorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	encysted zoospore germination on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0009847	biolink:NamedThing	spore germination	The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).	got7fsn_ti	spore germination on or near host										GO:0075005			biological_process											owl:Class	
GO:0102852	biolink:NamedThing	1-18:3-2-16:0-phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8319		molecular_function											owl:Class	
GO:0005894	biolink:NamedThing	interleukin-3 receptor complex	A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5.	got7fsn_ti	IL-3 receptor complex													cellular_component											owl:Class	
GO:0016979	biolink:NamedThing	lipoate-protein ligase activity	Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP.	got7fsn_ti	lipoate-protein ligase activity (lipoylation of glycine cleavage complex)|lipoate-protein ligase A activity|lipoate-protein ligase B activity										GO:0016978|GO:0008916|GO:0102315	EC:6.3.1.20|RHEA:49288|MetaCyc:RXN-13039|MetaCyc:RXN0-1141|MetaCyc:RXN-8655|MetaCyc:RXN-8654		molecular_function											owl:Class	
GO:0004608	biolink:NamedThing	phosphatidylethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine.	got7fsn_ti	S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase activity|phosphatidylethanolamine-S-adenosylmethionine methyltransferase activity|LMTase activity|lipid methyl transferase activity|phosphatidylethanolamine methyltransferase activity|PEMT|phosphatidylethanolamine-N-methylase activity											MetaCyc:2.1.1.17-RXN|EC:2.1.1.17|RHEA:11164|Reactome:R-HSA-1483174|KEGG_REACTION:R02056		molecular_function											owl:Class	
GO:0018578	biolink:NamedThing	protocatechuate 3,4-dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.	got7fsn_ti	protocatechuic acid oxidase activity|protocatechuic 3,4-oxygenase activity|protocatechuic 3,4-dioxygenase activity|protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)|protocatechuate oxygenase activity											MetaCyc:PROTOCATECHUATE-34-DIOXYGENASE-RXN|EC:1.13.11.3|RHEA:10084|UM-BBD_reactionID:r0143		molecular_function											owl:Class	
GO:0051012	biolink:NamedThing	microtubule sliding	The movement of one microtubule along another microtubule.	got7fsn_ti	microtubule translocation													biological_process											owl:Class	
GO:0031129	biolink:NamedThing	inductive cell-cell signaling	Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate.	got7fsn_ti	inductive cell-cell signalling													biological_process											owl:Class	
GO:0047875	biolink:NamedThing	ecdysone oxidase activity	Catalysis of the reaction: Ecdysone + O(2) = 3-dehydroecdysone + H(2)O(2).	got7fsn_ti	beta-ecdysone oxidase activity|ecdysone:oxygen 3-oxidoreductase activity											KEGG_REACTION:R02373|RHEA:11796|EC:1.1.3.16|MetaCyc:ECDYSONE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0044578	biolink:NamedThing	butyryl-CoA biosynthetic process	The chemical reactions and pathway resulting in the formation of butyryl-CoA.	got7fsn_ti	butyryl-CoA biosynthesis						jl	2012-04-19T04:23:26Z						biological_process											owl:Class	
GO:0006633	biolink:NamedThing	fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.	got7fsn_ti	fatty acid synthesis|fatty acid anabolism|fatty acid biosynthesis|fatty acid formation										GO:0000037	Wikipedia:Fatty_acid_synthesis|MetaCyc:FASYN-INITIAL-PWY|MetaCyc:PWY-5156|MetaCyc:PWY-4381		biological_process											owl:Class	
GO:0004954	biolink:NamedThing	prostanoid receptor activity	Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0004953	biolink:NamedThing	icosanoid receptor activity	Combining with an icosanoid to initiate a change in cell activity.	got7fsn_ti	eicosanoid receptor activity													molecular_function											owl:Class	
GO:0035144	biolink:NamedThing	anal fin morphogenesis	The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.	got7fsn_ti														biological_process											owl:Class	
GO:0035141	biolink:NamedThing	medial fin morphogenesis	The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.	got7fsn_ti	median fin morphogenesis|unpaired fin morphogenesis													biological_process											owl:Class	
GO:0106048	biolink:NamedThing	spermidine deacetylation	The modification of acetylspermadine by the removal of acetyl groups.	got7fsn_ti	N8-acetylspermidine deacetylation						hjd	2017-08-01T18:39:17Z						biological_process											owl:Class	
GO:0106047	biolink:NamedThing	polyamine deacetylation	The modification of acetylpolyamine by the removal of acetyl groups.	got7fsn_ti							hjd	2017-08-01T18:36:46Z						biological_process											owl:Class	
GO:0102604	biolink:NamedThing	naringenin,NADPH:oxygen oxidoreductase activity	Catalysis of the reaction: (S)-naringenin(1-) + O2 + NADPH + H+ <=> 2-hydroxy-2,3-dihydrogenistein-7-olate + NADP + H2O.	got7fsn_ti												RHEA:35487|EC:1.14.14.87|MetaCyc:RXN-1541		molecular_function											owl:Class	
GO:0048830	biolink:NamedThing	adventitious root development	The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.	got7fsn_ti														biological_process											owl:Class	
GO:0030370	biolink:NamedThing	intercellular adhesion molecule-3 receptor binding	Binding to a receptor for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1.	got7fsn_ti	intercellular adhesion molecule-3 receptor ligand|ICAM-3 receptor ligand|ICAM-3 receptor binding													molecular_function											owl:Class	
GO:0030778	biolink:NamedThing	columbamine O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine.	got7fsn_ti	S-adenosyl-L-methionine:columbamine O-methyltransferase activity											KEGG_REACTION:R03721|RHEA:15373|MetaCyc:2.1.1.118-RXN|EC:2.1.1.118		molecular_function											owl:Class	
GO:0005736	biolink:NamedThing	RNA polymerase I complex	RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.	got7fsn_ti	DNA-directed RNA polymerase I complex|DNA-directed RNA polymerase I activity													cellular_component											owl:Class	
GO:0034975	biolink:NamedThing	protein folding in endoplasmic reticulum	A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).	got7fsn_ti	protein folding in ER|oxidative protein folding													biological_process											owl:Class	
GO:0006457	biolink:NamedThing	protein folding	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.	got7fsn_ti	co-chaperonin activity|chaperonin ATPase activity|glycoprotein-specific chaperone activity|non-chaperonin molecular chaperone ATPase activity|chaperone activity|protein complex assembly, multichaperone pathway|chaperonin-mediated tubulin folding|alpha-tubulin folding|beta-tubulin folding|co-chaperone activity										GO:0007024|GO:0007022|GO:0007025	Wikipedia:Protein_folding		biological_process											owl:Class	
GO:0009250	biolink:NamedThing	glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.	got7fsn_ti	glucan synthesis|glucan formation|glucan anabolism|glucan biosynthesis													biological_process											owl:Class	
GO:0014002	biolink:NamedThing	astrocyte development	The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.	got7fsn_ti	astrocyte cell development													biological_process											owl:Class	
GO:0034245	biolink:NamedThing	mitochondrial DNA-directed RNA polymerase complex	A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.	got7fsn_ti	mitochondrial RNA polymerase complex|mitochondrial RNA polymerase holoenzyme complex													cellular_component											owl:Class	
GO:0110072	biolink:NamedThing	apical constriction involved in ventral furrow formation	The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.	got7fsn_ti							kmv	2017-12-06T17:04:49Z						biological_process											owl:Class	
GO:0003384	biolink:NamedThing	apical constriction involved in gastrulation	The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.	got7fsn_ti							dph	2009-12-09T07:35:38Z						biological_process											owl:Class	
GO:0070939	biolink:NamedThing	Dsl1/NZR complex	A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.	got7fsn_ti	Dsl1p complex|CATCHR family complex|NZR complex				See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.		mah	2009-09-22T03:41:38Z						cellular_component											owl:Class	
GO:0052873	biolink:NamedThing	FMN reductase (NADPH) activity	Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+.	got7fsn_ti	NADPH(2) dehydrogenase (FMN) activity|NADPH:FMN oxidoreductase activity|NADPH dehydrogenase (FMN) activity|NADPH2 dehydrogenase (FMN)|NADPH-FMN reductase activity|NADPH(2):FMN oxidoreductase activity|NADPH-dependent FMN reductase activity|SsuE|FMNH2:NADP+ oxidoreductase activity|flavin mononucleotide reductase activity|flavine mononucleotide reductase activity|NADPH2:FMN oxidoreductase activity|NADPH:flavin oxidoreductase activity											EC:1.5.1.38|EC:1.5.1.39|Reactome:R-HSA-1222399|KEGG_REACTION:R05706|RHEA:21624		molecular_function											owl:Class	
GO:0070186	biolink:NamedThing	growth hormone activity	The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth.	got7fsn_ti	pituitary growth hormone activity|GH activity|placental growth hormone activity													molecular_function											owl:Class	
GO:0033134	biolink:NamedThing	ubiquitin activating enzyme binding	Binding to a ubiquitin activating enzyme, any of the E1 proteins.	got7fsn_ti														molecular_function											owl:Class	
GO:0010721	biolink:NamedThing	negative regulation of cell development	Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0098953	biolink:NamedThing	receptor diffusion trapping	The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region.  This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.	got7fsn_ti														biological_process											owl:Class	
GO:0042377	biolink:NamedThing	vitamin K catabolic process	The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.	got7fsn_ti	naphthoquinone catabolic process|naphthoquinone catabolism|vitamin K degradation|vitamin K catabolism|vitamin K breakdown													biological_process											owl:Class	
GO:0061026	biolink:NamedThing	cardiac muscle tissue regeneration	The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.	got7fsn_ti							dph	2010-02-09T08:25:51Z						biological_process											owl:Class	
GO:0042246	biolink:NamedThing	tissue regeneration	The regrowth of lost or destroyed tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0010996	biolink:NamedThing	response to auditory stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.	got7fsn_ti	response to sound|response to sound stimulus						tb	2009-06-10T11:09:38Z						biological_process											owl:Class	
GO:0009612	biolink:NamedThing	response to mechanical stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.	got7fsn_ti	mechanical stimulus response|chemi-mechanical coupling													biological_process											owl:Class	
GO:0070867	biolink:NamedThing	mating projection tip membrane	The portion of the plasma membrane surrounding a mating projection tip.	got7fsn_ti	mating projection membrane fusion domain|shmoo tip membrane						mah	2009-08-19T04:05:58Z						cellular_component											owl:Class	
GO:1990595	biolink:NamedThing	mast cell secretagogue receptor activity	Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells.	got7fsn_ti							sp	2014-12-22T10:04:43Z						molecular_function											owl:Class	
GO:0048720	biolink:NamedThing	posterior cibarial plate morphogenesis	The process in which the anatomical structures of the posterior cibarial plate are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0050268	biolink:NamedThing	coniferyl-alcohol dehydrogenase activity	Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH.	got7fsn_ti	coniferyl-alcohol:NADP+ oxidoreductase activity											MetaCyc:RXN-2602|RHEA:22444|EC:1.1.1.194		molecular_function											owl:Class	
GO:0003148	biolink:NamedThing	outflow tract septum morphogenesis	The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.	got7fsn_ti							tb	2009-09-22T07:51:01Z						biological_process											owl:Class	
GO:0060411	biolink:NamedThing	cardiac septum morphogenesis	The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.	got7fsn_ti	heart septum morphogenesis										GO:0003280			biological_process											owl:Class	
GO:0050218	biolink:NamedThing	propionate-CoA ligase activity	Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.	got7fsn_ti	propanoate:CoA ligase (AMP-forming)|propionyl-CoA synthetase activity											RHEA:20373|MetaCyc:PROPIONATE--COA-LIGASE-RXN|EC:6.2.1.17		molecular_function											owl:Class	
GO:0031689	biolink:NamedThing	A3 adenosine receptor binding	Binding to an A3 adenosine receptor.	got7fsn_ti	A3 adenosine receptor ligand													molecular_function											owl:Class	
GO:0031685	biolink:NamedThing	adenosine receptor binding	Binding to an adenosine receptor.	got7fsn_ti	adenosine receptor ligand													molecular_function											owl:Class	
GO:0051305	biolink:NamedThing	chromosome movement towards spindle pole	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.	got7fsn_ti	chromosome movement to spindle pole|chromosome migration to spindle pole|chromosome movement													biological_process											owl:Class	
GO:0009538	biolink:NamedThing	photosystem I reaction center	A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin.	got7fsn_ti	photosystem I reaction centre													cellular_component											owl:Class	
GO:0047864	biolink:NamedThing	dimethylaniline-N-oxide aldolase activity	Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.	got7fsn_ti	microsomal oxidase II|N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming)|N,N-dimethylaniline-N-oxide formaldehyde-lyase activity|microsomal N-oxide dealkylase activity											RHEA:19321|MetaCyc:DIMETHYLANILINE-N-OXIDE-ALDOLASE-RXN|EC:4.1.2.24|KEGG_REACTION:R03345		molecular_function											owl:Class	
GO:0000447	biolink:NamedThing	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	got7fsn_ti	endonucleolytic cleavage at A2													biological_process											owl:Class	
GO:0000479	biolink:NamedThing	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae.	got7fsn_ti														biological_process											owl:Class	
GO:0018623	biolink:NamedThing	benzoate 1,2-dioxygenase activity	Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.	got7fsn_ti	benzoate dioxygenase activity|benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating)|benzoic hydroxylase activity|benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)|benzoate hydroxylase activity											RHEA:12633|UM-BBD_enzymeID:e0154|EC:1.14.12.10|MetaCyc:BENZOATE-12-DIOXYGENASE-RXN		molecular_function											owl:Class	
GO:0102203	biolink:NamedThing	brassicasterol glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + brassicasterol <=> UDP(3-) + 3-O-beta-D-glucosyl-brassicasterol + H+.	got7fsn_ti												RHEA:61840|MetaCyc:RXN-12125|EC:2.4.1.173		molecular_function											owl:Class	
GO:0102717	biolink:NamedThing	DIBOA-glucoside oxygenase activity	Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide.	got7fsn_ti												RHEA:32115|EC:1.14.11.59|MetaCyc:RXN-6685		molecular_function											owl:Class	
GO:0070327	biolink:NamedThing	thyroid hormone transport	The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	triiodothyronine transport|thyroxine transport													biological_process											owl:Class	
GO:0009914	biolink:NamedThing	hormone transport	The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0140231	biolink:NamedThing	anterograde axonal transport of neurotransmitter receptor complex	The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons.	got7fsn_ti							pg	2018-07-09T09:41:37Z						biological_process											owl:Class	
GO:0099641	biolink:NamedThing	anterograde axonal protein transport	The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.	got7fsn_ti	anterograde axon cargo transport													biological_process											owl:Class	
GO:0051615	biolink:NamedThing	histamine uptake	The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	got7fsn_ti	histamine import													biological_process											owl:Class	
GO:0001504	biolink:NamedThing	neurotransmitter uptake	The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	got7fsn_ti	neurotransmitter import|neurotransmitter recycling|neurotransmitter import into neuron|neurotransmitter import into glial cell													biological_process											owl:Class	
GO:0050097	biolink:NamedThing	methylaspartate mutase activity	Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate.	got7fsn_ti	glutamate mutase activity|glutamic isomerase activity|beta-methylaspartate-glutamate mutase activity|glutamic acid mutase activity|b-methylaspartate-glutamate mutase activity|glutamic mutase activity|L-threo-3-methylaspartate carboxy-aminomethylmutase activity|methylaspartic acid mutase activity|glutamate isomerase activity|glutamic acid isomerase activity											EC:5.4.99.1|RHEA:12857|KEGG_REACTION:R00262|MetaCyc:METHYLASPARTATE-MUTASE-RXN		molecular_function											owl:Class	
GO:0008872	biolink:NamedThing	glucarate dehydratase activity	Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O.	got7fsn_ti	D-glucarate hydro-lyase activity|D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)|D-glucarate dehydratase activity											MetaCyc:GLUCARDEHYDRA-RXN|EC:4.2.1.40|RHEA:14573		molecular_function											owl:Class	
GO:0046010	biolink:NamedThing	positive regulation of circadian sleep/wake cycle, non-REM sleep	Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.	got7fsn_ti	stimulation of circadian sleep/wake cycle, non-REM sleep|up regulation of circadian sleep/wake cycle, non-REM sleep|positive regulation of non-REM sleep|activation of circadian sleep/wake cycle, non-REM sleep|upregulation of circadian sleep/wake cycle, non-REM sleep|up-regulation of circadian sleep/wake cycle, non-REM sleep													biological_process											owl:Class	
GO:0050448	biolink:NamedThing	beta-cyclopiazonate dehydrogenase activity	Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2).	got7fsn_ti	beta-cyclopiazonate:acceptor oxidoreductase (cyclizing)|beta-cyclopiazonate oxidocyclase activity|beta-cyclopiazonate:(acceptor) oxidoreductase (cyclizing)|b-cyclopiazonate dehydrogenase activity|beta-cyclopiazonic oxidocyclase activity											KEGG_REACTION:R04080|RHEA:14525|EC:1.21.99.1|MetaCyc:BETA-CYCLOPIAZONATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0007300	biolink:NamedThing	ovarian nurse cell to oocyte transport	Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster.	got7fsn_ti	nurse cell to oocyte transport													biological_process											owl:Class	
GO:0106367	biolink:NamedThing	dGTP dependent (deoxy)nucleoside -phosphate kinase activity	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dGTP = a 2'-deoxyribonucleoside 5'-diphosphate + dGDP.	got7fsn_ti							hjd	2021-03-11T20:06:53Z				RHEA:62128		molecular_function											owl:Class	
GO:0097391	biolink:NamedThing	chemokine (C-X-C motif) ligand 13 production	The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CXCL13 production						pr	2012-10-23T07:58:28Z						biological_process											owl:Class	
GO:0002034	biolink:NamedThing	maintenance of blood vessel diameter homeostasis by renin-angiotensin	The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system.	got7fsn_ti	renin-angiotensin regulation of blood vessel size|regulation of blood vessel diameter by renin-angiotensin|regulation of blood vessel size by renin-angiotensin	https://github.com/geneontology/go-ontology/issues/12253												biological_process											owl:Class	
GO:0003081	biolink:NamedThing	regulation of systemic arterial blood pressure by renin-angiotensin	The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.	got7fsn_ti	blood pressure regulation by renin-angiotensin													biological_process											owl:Class	
GO:0007612	biolink:NamedThing	learning	Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.	got7fsn_ti												Wikipedia:Learning		biological_process											owl:Class	
GO:0007611	biolink:NamedThing	learning or memory	The acquisition and processing of information and/or the storage and retrieval of this information over time.	got7fsn_ti														biological_process											owl:Class	
GO:0103000	biolink:NamedThing	UDP-glucose:4-hydroxylamino-2,6-dinitrotoluene-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 4-hydroxylamino-2,6-dinitrotoluene <=> 4-hydroxylamino-2,6-dinitrotoluene-O-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-9748		molecular_function											owl:Class	
GO:0097277	biolink:NamedThing	cellular urea homeostasis	Any biological process involved in the maintenance of an internal steady state of urea at the level of the cell.	got7fsn_ti							pr	2012-03-22T02:57:08Z						biological_process											owl:Class	
GO:0097274	biolink:NamedThing	urea homeostasis	Any biological process involved in the maintenance of an internal steady state of urea.	got7fsn_ti							pr	2012-03-22T02:53:39Z						biological_process											owl:Class	
GO:0033658	biolink:NamedThing	modification by symbiont of host chloroplast thylakoid	The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0033657	biolink:NamedThing	modification by symbiont of host chloroplast part	The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0047119	biolink:NamedThing	2-methyl-branched-chain-enoyl-CoA reductase activity	Catalysis of the reaction: 2-methylbutanoyl-CoA + NAD(+) = 2-methylbut-2-enoyl-CoA + H(+) + NADH.	got7fsn_ti	2-methyl-branched-chain-acyl-CoA:NAD+ 2-oxidoreductase activity											EC:1.3.1.52|RHEA:24532|MetaCyc:1.3.1.52-RXN|KEGG_REACTION:R03169		molecular_function											owl:Class	
GO:0098860	biolink:NamedThing	actin filament bundle of stereocilium	A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium.  Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0097518	biolink:NamedThing	parallel actin filament bundle	An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.	got7fsn_ti							pr	2013-10-16T15:42:17Z						cellular_component											owl:Class	
GO:0047650	biolink:NamedThing	alkylglycerone kinase activity	Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H(+).	got7fsn_ti	alkyldihydroxyacetone kinase (phosphorylating)|alkyldihydroxyacetone kinase activity|ATP:O-alkylglycerone phosphotransferase activity											EC:2.7.1.84|MetaCyc:ALKYLGLYCERONE-KINASE-RXN|KEGG_REACTION:R03944|RHEA:23088		molecular_function											owl:Class	
GO:0048096	biolink:NamedThing	chromatin-mediated maintenance of transcription	Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21730			Note that this process is the opposite of chromatin silencing. This regulation is exemplified by members of the trithorax group, which maintain the active state of homeotic gene transcription. Do not confuse with GO:0140673 ; label "chromatin maintenance during transcription elongation, which describes the reforming of chromatin after RNA polymerase II passage.									biological_process											owl:Class	
GO:0045893	biolink:NamedThing	positive regulation of transcription, DNA-templated	Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	got7fsn_ti	stimulation of transcription, DNA-dependent|transcription activator activity|positive regulation of gene-specific transcription|up regulation of transcription, DNA-dependent|upregulation of transcription, DNA-dependent|activation of transcription, DNA-dependent|stimulation of gene-specific transcription|activation of gene-specific transcription|positive regulation of cellular transcription, DNA-dependent|up regulation of gene-specific transcription|positive regulation of transcription, DNA-dependent|up-regulation of gene-specific transcription|up-regulation of transcription, DNA-dependent|upregulation of gene-specific transcription										GO:0045941|GO:0061020|GO:0043193			biological_process											owl:Class	
GO:0035325	biolink:NamedThing	Toll-like receptor binding	Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.	got7fsn_ti	TLR binding						bf	2010-02-26T10:11:55Z						molecular_function											owl:Class	
GO:0016182	biolink:NamedThing	synaptic vesicle budding from endosome	Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes.	got7fsn_ti	synaptic vesicle budding involved in synaptic vesicle exocytosis|endosome to synaptic vesicle budding													biological_process											owl:Class	
GO:0047806	biolink:NamedThing	cytochrome-c3 hydrogenase activity	Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3.	got7fsn_ti	cytochrome hydrogenase activity|hydrogen:ferricytochrome-c3 oxidoreductase activity|H2:ferricytochrome c3 oxidoreductase activity|H(2):ferricytochrome c3 oxidoreductase activity|cytochrome c3 reductase activity											EC:1.12.2.1|UM-BBD_enzymeID:e0481|RHEA:20625|MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN		molecular_function											owl:Class	
GO:0016697	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome.	got7fsn_ti											GO:0016698	EC:1.12.2.-		molecular_function											owl:Class	
GO:0048574	biolink:NamedThing	long-day photoperiodism, flowering	A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.	got7fsn_ti	response to long-day, flowering|short-night photoperiodism, flowering|long-day photoperiodic control of inflorescence development|long-day photoperiodic control of flowering|long-day photoperiodic control of flowering time|response to short-night, flowering													biological_process											owl:Class	
GO:0048571	biolink:NamedThing	long-day photoperiodism	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length.	got7fsn_ti	response to long-day photoperiod|short-night photoperiodism|response to short-night|response to long-day													biological_process											owl:Class	
GO:0010341	biolink:NamedThing	gibberellin carboxyl-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester.	got7fsn_ti														molecular_function											owl:Class	
GO:0010340	biolink:NamedThing	carboxyl-O-methyltransferase activity	Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester.	got7fsn_ti														molecular_function											owl:Class	
GO:0034289	biolink:NamedThing	detection of maltose stimulus	The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of maltose stimulus													biological_process											owl:Class	
GO:0034286	biolink:NamedThing	response to maltose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.	got7fsn_ti	response to maltose stimulus													biological_process											owl:Class	
GO:0055019	biolink:NamedThing	negative regulation of cardiac muscle fiber development	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.	got7fsn_ti	downregulation of cardiac muscle fiber development|down-regulation of cardiac muscle fiber development|down regulation of cardiac muscle fiber development|negative regulation of cardiac muscle fibre development|negative regulation of heart muscle fiber development|inhibition of cardiac muscle fiber development													biological_process											owl:Class	
GO:0019705	biolink:NamedThing	protein-cysteine S-myristoyltransferase activity	Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein].	got7fsn_ti												RHEA:59736		molecular_function											owl:Class	
GO:0019107	biolink:NamedThing	myristoyltransferase activity	Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule.	got7fsn_ti												Reactome:R-HSA-162914|Reactome:R-HSA-141367		molecular_function											owl:Class	
GO:0000347	biolink:NamedThing	THO complex	The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.	got7fsn_ti														cellular_component											owl:Class	
GO:0001675	biolink:NamedThing	acrosome assembly	The formation of the acrosome from the spermatid Golgi.	got7fsn_ti	acrosome formation													biological_process											owl:Class	
GO:0072106	biolink:NamedThing	regulation of ureteric bud formation	Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.	got7fsn_ti							mah	2010-02-12T02:34:40Z						biological_process											owl:Class	
GO:0090183	biolink:NamedThing	regulation of kidney development	Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti	regulation of nephrogenesis						tb	2009-12-18T10:50:56Z						biological_process											owl:Class	
GO:0033431	biolink:NamedThing	CGA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CGA codon.	got7fsn_ti	arginine tRNA				Note that in the standard genetic code, CGA codes for arginine.									molecular_function											owl:Class	
GO:0031735	biolink:NamedThing	CCR10 chemokine receptor binding	Binding to a CCR10 chemokine receptor.	got7fsn_ti	CCR10 chemokine receptor ligand													molecular_function											owl:Class	
GO:1990027	biolink:NamedThing	S bouton	Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles.	got7fsn_ti							pr	2013-02-06T10:35:12Z				NIF_Subcellular:nlx_subcell_100207		cellular_component											owl:Class	
GO:0018263	biolink:NamedThing	isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine	The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine.	got7fsn_ti												RESID:AA0216		biological_process											owl:Class	
GO:0140081	biolink:NamedThing	glycosylated region protein binding	Binding to a glycosylated region of a protein.	got7fsn_ti							pg	2017-07-25T10:58:31Z						molecular_function											owl:Class	
GO:0035626	biolink:NamedThing	juvenile hormone mediated signaling pathway	A series of molecular signals initiated by the binding of juvenile hormone to a receptor, and ending with regulation of cell state or activity.	got7fsn_ti	juvenile hormone-mediated signaling pathway|juvenile hormone mediated signalling pathway						bf	2010-12-08T04:45:25Z						biological_process											owl:Class	
GO:0032989	biolink:NamedThing	cellular component morphogenesis	The process in which cellular structures, including whole cells or cell parts, are generated and organized.	got7fsn_ti	cellular structure morphogenesis													biological_process											owl:Class	
GO:0071355	biolink:NamedThing	cellular response to interleukin-9	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.	got7fsn_ti	cellular response to IL-9						mah	2009-12-11T02:51:26Z						biological_process											owl:Class	
GO:0047915	biolink:NamedThing	ganglioside galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine.	got7fsn_ti	GM1-synthase activity|uridine diphosphogalactose-ceramide galactosyltransferase activity|UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase activity|UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity|uridine diphosphogalactose-GM2 galactosyltransferase activity|UDPgalactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity|UDP-galactose-GM2 galactosyltransferase activity|UDP-galactose-GM2 ganglioside galactosyltransferase activity|uridine diphosphate D-galactose:glycolipid galactosyltransferase activity|UDP galactose-LAC Tet-ceramide alpha-galactosyltransferase activity|UDPgalactose-ceramide galactosyltransferase activity											EC:2.4.1.62|MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN|RHEA:16773		molecular_function											owl:Class	
GO:0003318	biolink:NamedThing	cell migration to the midline involved in heart development	The orderly movement of a cell toward the midline that contributes to the progression of the heart over time.	got7fsn_ti							dph	2009-10-27T09:15:43Z						biological_process											owl:Class	
GO:0050571	biolink:NamedThing	1,5-anhydro-D-fructose reductase activity	Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.	got7fsn_ti	1,5-anhydro-D-glucitol:NADP+ oxidoreductase activity|AF reductase activity											MetaCyc:1.1.1.263-RXN|KEGG_REACTION:R05682|RHEA:20665|EC:1.1.1.263		molecular_function											owl:Class	
GO:0009756	biolink:NamedThing	carbohydrate mediated signaling	A series of molecular signals mediated by the detection of carbohydrate.	got7fsn_ti	carbohydrate mediated signalling													biological_process											owl:Class	
GO:0043987	biolink:NamedThing	histone H3-S10 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a serine residue at position 10 of the histone.	got7fsn_ti	histone H3S10 phosphorylation|histone H3 phosphorylation at S10										GO:0043986			biological_process											owl:Class	
GO:0008236	biolink:NamedThing	serine-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	got7fsn_ti	serine protease activity											Reactome:R-HSA-3132753|Reactome:R-HSA-6801766|Reactome:R-HSA-1461993|Reactome:R-HSA-2022383		molecular_function											owl:Class	
GO:0017171	biolink:NamedThing	serine hydrolase activity	Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	got7fsn_ti														molecular_function											owl:Class	
GO:0072150	biolink:NamedThing	juxtaglomerulus cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell.	got7fsn_ti							mah	2010-02-24T02:09:49Z						biological_process											owl:Class	
GO:0043233	biolink:NamedThing	organelle lumen	The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.	got7fsn_ti														cellular_component											owl:Class	
GO:0047879	biolink:NamedThing	erythronolide synthase activity	Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.	got7fsn_ti	malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing)|erythronolide condensing enzyme activity											MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN|RHEA:23068|EC:2.3.1.94		molecular_function											owl:Class	
GO:0008932	biolink:NamedThing	lytic endotransglycosylase activity	Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends.	got7fsn_ti	murein lytic endotransglycosylase E activity											EC:2.4.99.-		molecular_function											owl:Class	
GO:0008933	biolink:NamedThing	lytic transglycosylase activity	Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues.	got7fsn_ti	peptidoglycan lytic transglycosylase activity|murein transglycosylase B activity											EC:3.2.1.-		molecular_function											owl:Class	
GO:0039563	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1).	got7fsn_ti	inhibition by virus of host STAT1 activity|inhibition of host STAT1 by virus|suppression by virus of host STAT1 activity	https://github.com/geneontology/go-ontology/issues/21963			This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-03-12T02:35:39Z						biological_process											owl:Class	
GO:0039562	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of STAT activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.	got7fsn_ti	inhibition by virus of host STAT activity|suppression by virus of host signal transducer and activator of transcription activity|suppression by virus of host STAT activity	https://github.com/geneontology/go-ontology/issues/21963			This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-03-12T02:28:39Z						biological_process											owl:Class	
GO:1990710	biolink:NamedThing	MutS complex	A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations.	got7fsn_ti	MutS mismatch repair complex				An example of this is MutS in E. coli (UniProt symbol P23909) in PMID:21666597 (inferred from physical interaction).		bhm	2015-03-25T11:42:56Z						cellular_component											owl:Class	
GO:0032300	biolink:NamedThing	mismatch repair complex	Any complex formed of proteins that act in mismatch repair.	got7fsn_ti														cellular_component											owl:Class	
GO:0008463	biolink:NamedThing	formylmethionine deformylase activity	Catalysis of the reaction: N-formyl-L-methionine + H(2)O = L-methionine + formate.	got7fsn_ti	N-formyl-L-methionine amidohydrolase activity											EC:3.5.1.31|RHEA:17781|MetaCyc:FORMYLMETHIONINE-DEFORMYLASE-RXN|KEGG_REACTION:R00653		molecular_function											owl:Class	
GO:0018614	biolink:NamedThing	ethylbenzene dioxygenase activity	Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene.	got7fsn_ti												UM-BBD_reactionID:r0247|EC:1.14.12.-		molecular_function											owl:Class	
GO:0044101	biolink:NamedThing	(R)-citramalyl-CoA lyase activity	Catalysis of the reaction: (R)-citramalyl-CoA = pyruvate + acetyl-CoA.	got7fsn_ti	R-citramalyl-CoA lyase activity|Ccl						jl	2009-07-09T03:14:15Z				EC:4.1.3.46|MetaCyc:RXN-8967		molecular_function											owl:Class	
GO:0008888	biolink:NamedThing	glycerol dehydrogenase [NAD+] activity	Catalysis of the reaction: glycerol + NAD(+) = glycerone + H(+) + NADH.	got7fsn_ti	glycerol dehydrogenase activity|NAD-linked glycerol dehydrogenase activity											RHEA:13769|MetaCyc:GLYCDEH-RXN|EC:1.1.1.6|KEGG_REACTION:R01034		molecular_function											owl:Class	
GO:1990042	biolink:NamedThing	glycerol dehydrogenase [NAD(P)+] activity	Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced.	got7fsn_ti	glycerol dehydrogenase activity, NAD or NADP as acceptor						rb	2013-02-14T00:34:45Z						molecular_function											owl:Class	
GO:0003285	biolink:NamedThing	septum secundum development	The progression of the septum secundum over time, from its initial formation to the mature structure.	got7fsn_ti							dph	2009-10-20T10:21:13Z						biological_process											owl:Class	
GO:0003283	biolink:NamedThing	atrial septum development	The progression of the atrial septum over time, from its initial formation to the mature structure.	got7fsn_ti							dph	2009-10-20T10:10:38Z						biological_process											owl:Class	
GO:0019595	biolink:NamedThing	non-phosphorylated glucose catabolic process	The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.	got7fsn_ti	non-phosphorylated glucose breakdown|non-phosphorylated glucose catabolism|non-phosphorylated glucose degradation											MetaCyc:NPGLUCAT-PWY		biological_process											owl:Class	
GO:0046430	biolink:NamedThing	non-phosphorylated glucose metabolic process	The chemical reactions and pathways involving non-phosphorylated forms of glucose.	got7fsn_ti	non-phosphorylated glucose metabolism													biological_process											owl:Class	
GO:0050608	biolink:NamedThing	vanillin dehydrogenase activity	Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate.	got7fsn_ti	vanillin:NAD+ oxidoreductase activity											MetaCyc:1.2.1.67-RXN|RHEA:13309|KEGG_REACTION:R05699|EC:1.2.1.67		molecular_function											owl:Class	
GO:0030677	biolink:NamedThing	ribonuclease P complex	A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.	got7fsn_ti	RNase P complex				Note that chloroplasts possess a complex that is called 'RNase P' because it catalyzes pre-tRNA cleavage, but the chloroplast complex appears not to contain RNA.									cellular_component											owl:Class	
GO:0080165	biolink:NamedThing	callose deposition in phloem sieve plate	Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	got7fsn_ti							dhl	2010-09-23T04:12:49Z						biological_process											owl:Class	
GO:0004056	biolink:NamedThing	argininosuccinate lyase activity	Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.	got7fsn_ti	arginine-succinate lyase activity|argininosuccinic acid lyase activity|arginosuccinase activity|omega-N-(L-arginino)succinate arginine-lyase activity|N-(L-argininosuccinate) arginine-lyase activity|2-(omega-N-L-arginino)succinate arginine-lyase (fumarate-forming)|2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)											EC:4.3.2.1|MetaCyc:ARGSUCCINLYA-RXN|RHEA:24020|Reactome:R-HSA-70573		molecular_function											owl:Class	
GO:0070880	biolink:NamedThing	fungal-type cell wall beta-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.	got7fsn_ti	fungal-type cell wall beta-glucan anabolism|fungal-type cell wall beta-glucan synthesis|fungal-type cell wall beta-glucan formation|fungal-type cell wall beta-glucan biosynthesis						mah	2009-08-21T02:48:24Z						biological_process											owl:Class	
GO:0051278	biolink:NamedThing	fungal-type cell wall polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.	got7fsn_ti	chitin- and beta-glucan-containing cell wall polysaccharide biosynthetic process|cell wall polysaccharide synthesis|cell wall polysaccharide anabolism|cell wall polysaccharide formation													biological_process											owl:Class	
GO:0071224	biolink:NamedThing	cellular response to peptidoglycan	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.	got7fsn_ti							mah	2009-12-03T01:36:38Z						biological_process											owl:Class	
GO:0071219	biolink:NamedThing	cellular response to molecule of bacterial origin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.	got7fsn_ti	cellular response to bacterial associated molecule|cellular response to bacteria associated molecule|cellular response to bacterium associated molecule						mah	2009-12-03T01:22:00Z						biological_process											owl:Class	
GO:0070446	biolink:NamedThing	negative regulation of oligodendrocyte progenitor proliferation	Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.	got7fsn_ti	negative regulation of oligodendrocyte precursor proliferation													biological_process											owl:Class	
GO:0014014	biolink:NamedThing	negative regulation of gliogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.	got7fsn_ti	inhibition of gliogenesis|down regulation of gliogenesis|downregulation of gliogenesis|down-regulation of gliogenesis													biological_process											owl:Class	
GO:1900557	biolink:NamedThing	emericellamide biosynthetic process	The chemical reactions and pathways resulting in the formation of emericellamide.	got7fsn_ti	emericellamide biosynthesis|emericellamide synthesis|emericellamide anabolism|emericellamide formation						di	2012-05-15T01:33:31Z						biological_process											owl:Class	
GO:0061107	biolink:NamedThing	seminal vesicle development	The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.	got7fsn_ti							dph	2010-04-30T10:17:30Z						biological_process											owl:Class	
GO:0008700	biolink:NamedThing	4-hydroxy-2-oxoglutarate aldolase activity	Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.	got7fsn_ti	4-hydroxy-2-ketoglutarate aldolase activity|2-keto-4-hydroxybutyrate aldolase activity|2-keto-4-hydroxyglutaric aldolase activity|4-hydroxy-2-ketoglutaric aldolase activity|4-hydroxy-2-oxoglutarate glyoxylate-lyase activity|KHG-aldolase activity|hydroxyketoglutarate aldolase activity|DL-4-hydroxy-2-ketoglutarate aldolase activity|2-oxo-4-hydroxyglutaric aldolase activity|hydroxyketoglutaric aldolase activity|4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)|2-keto-4-hydroxyglutarate aldolase activity|2-oxo-4-hydroxyglutarate aldolase activity											EC:4.1.3.16|RHEA:18169|Reactome:R-HSA-6784423|MetaCyc:4OH2OXOGLUTARALDOL-RXN		molecular_function											owl:Class	
GO:0080189	biolink:NamedThing	primary growth	Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed.	got7fsn_ti					Has its inception in the apical meristems (PO:0020144) and continues in their derivative meristems - protoderm (PO:0006210) and procambium (PO:0025275) - even in older tissues. Primary and secondary growth can occur simultaneously in the same organism.		dhl	2012-12-06T15:20:41Z						biological_process											owl:Class	
GO:0008428	biolink:NamedThing	ribonuclease inhibitor activity	Binds to and stops, prevents or reduces the activity of ribonuclease.	got7fsn_ti														molecular_function											owl:Class	
GO:0009062	biolink:NamedThing	fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.	got7fsn_ti	fatty acid catabolism|fatty acid degradation|fatty acid breakdown											Wikipedia:Fatty_acid_degradation		biological_process											owl:Class	
GO:0021762	biolink:NamedThing	substantia nigra development	The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).	got7fsn_ti														biological_process											owl:Class	
GO:0021928	biolink:NamedThing	basket cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0021923	biolink:NamedThing	cell proliferation in hindbrain ventricular zone	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.	got7fsn_ti														biological_process											owl:Class	
GO:0080046	biolink:NamedThing	quercetin 4'-O-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule.	got7fsn_ti												MetaCyc:RXN-10788		molecular_function											owl:Class	
GO:0052482	biolink:NamedThing	defense response by cell wall thickening	A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism.	got7fsn_ti	cell wall thickening during defense response													biological_process											owl:Class	
GO:0017007	biolink:NamedThing	protein-bilin linkage	The covalent linkage of bilin and a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0031142	biolink:NamedThing	induction of conjugation upon nitrogen starvation	The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.	got7fsn_ti														biological_process											owl:Class	
GO:0097232	biolink:NamedThing	lamellar body membrane	The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.	got7fsn_ti							pr	2012-01-26T10:28:42Z						cellular_component											owl:Class	
GO:0009585	biolink:NamedThing	red, far-red light phototransduction	The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.	got7fsn_ti	phytochrome signaling pathway|red-sensitive opsin													biological_process											owl:Class	
GO:0032625	biolink:NamedThing	interleukin-21 production	The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-21 production|interleukin-21 biosynthetic process|interleukin-21 secretion										GO:0042238|GO:0072619			biological_process											owl:Class	
GO:0097581	biolink:NamedThing	lamellipodium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.	got7fsn_ti							pr	2014-02-28T16:08:56Z						biological_process											owl:Class	
GO:0030030	biolink:NamedThing	cell projection organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.	got7fsn_ti	cell surface structure organization and biogenesis|cell projection organization and biogenesis|cell projection organisation													biological_process											owl:Class	
GO:0005575	biolink:NamedThing	cellular_component	A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).	got7fsn_ti	subcellular entity|cell or subcellular entity|cellular component				Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.						GO:0008372	NIF_Subcellular:sao1337158144		cellular_component											owl:Class	
GO:0102838	biolink:NamedThing	1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8298|EC:1.14.19.23		molecular_function											owl:Class	
GO:0018131	biolink:NamedThing	oxazole or thiazole biosynthetic process	The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.	got7fsn_ti	oxazole or thiazole synthesis|oxazole or thiazole formation|oxazole or thiazole anabolism|oxazole or thiazole biosynthesis													biological_process											owl:Class	
GO:0018130	biolink:NamedThing	heterocycle biosynthetic process	The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).	got7fsn_ti	heterocycle biosynthesis|heterocycle formation|heterocycle anabolism|heterocycle synthesis													biological_process											owl:Class	
GO:0035006	biolink:NamedThing	melanization defense response	The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.	got7fsn_ti	melanization defence response													biological_process											owl:Class	
GO:0006582	biolink:NamedThing	melanin metabolic process	The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.	got7fsn_ti	melanin metabolism													biological_process											owl:Class	
GO:0140493	biolink:NamedThing	very long-chain fatty acid beta-oxidation	A fatty acid beta-oxidation pathway acting on fatty acid which has a chain length greater than C22 in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19735					pg	2020-07-10T08:39:22Z						biological_process											owl:Class	
GO:0042760	biolink:NamedThing	very long-chain fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of a fatty acid which has a chain length greater than C22.	got7fsn_ti	very-long-chain fatty acid catabolic process|very-long-chain fatty acid catabolism|very-long-chain fatty acid degradation|very-long-chain fatty acid breakdown													biological_process											owl:Class	
GO:0035367	biolink:NamedThing	positive regulation of thymine transport	Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	positive regulation of 5-methyluracil transport						bf	2010-03-11T10:24:25Z						biological_process											owl:Class	
GO:0032241	biolink:NamedThing	positive regulation of nucleobase-containing compound transport	Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|activation of nucleobase, nucleoside, nucleotide and nucleic acid transport|up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport													biological_process											owl:Class	
GO:0046029	biolink:NamedThing	mannitol dehydrogenase activity	Catalysis of the reaction: D-mannitol + NAD(+) = D-mannose + H(+) + NADH.	got7fsn_ti	MTD activity|NAD-dependent mannitol dehydrogenase activity|mannitol:NAD+ 1-oxidoreductase activity											RHEA:15029|MetaCyc:1.1.1.255-RXN|EC:1.1.1.255|KEGG_REACTION:R07135		molecular_function											owl:Class	
GO:0052390	biolink:NamedThing	induction by symbiont of host innate immune response	The activation by a symbiont of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of host innate immune response|activation by organism of host innate immune response|activation by symbiont of host innate immunity|stimulation by symbiont of host innate immunity|up regulation by symbiont of host innate immunity|positive regulation of innate immune response in other organism|induction of host innate immunity|up-regulation by symbiont of host innate immunity|induction by organism of host innate immune response|induction by organism of innate immune response in other organism involved in symbiotic interaction|positive regulation by symbiont of host innate immunity|upregulation by symbiont of host innate immunity|induction by symbiont of host innate immunity|activation by organism of host innate immunity|positive regulation by symbiont of host innate immune response										GO:0052305|GO:0052166|GO:0052382			biological_process											owl:Class	
GO:0042074	biolink:NamedThing	cell migration involved in gastrulation	The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).	got7fsn_ti														biological_process											owl:Class	
GO:0106059	biolink:NamedThing	tRNA (cytidine 56-2'-O)-methyltransferase	Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA.	got7fsn_ti							hjd	2017-10-05T19:02:22Z						molecular_function											owl:Class	
GO:0052666	biolink:NamedThing	tRNA (cytosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine.	got7fsn_ti	S-adenosyl-L-methionine:tRNA (cytosine-2'-O-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA cytosine-2'-O-methyltransferase activity|transfer ribonucleate cytosine 2'-methyltransferase activity|tRNA cytosine 2'-methyltransferase activity|tRNA (cytosine 2')-methyltransferase activity|tRNA cytosine-2'-O-methyltransferase activity						ai	2010-10-11T01:05:47Z				Reactome:R-HSA-6788684|MetaCyc:RXN0-5143|Reactome:R-HSA-9024159|Reactome:R-HSA-6788668		molecular_function											owl:Class	
GO:0060088	biolink:NamedThing	auditory receptor cell stereocilium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.	got7fsn_ti	auditory receptor cell stereocilium organization and biogenesis|auditory receptor cell stereocilium organisation													biological_process											owl:Class	
GO:0060122	biolink:NamedThing	inner ear receptor cell stereocilium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.	got7fsn_ti	inner ear receptor stereocilium organisation|inner ear hair cell receptor stereocilium organization|inner ear receptor stereocilium organization and biogenesis													biological_process											owl:Class	
GO:0015234	biolink:NamedThing	thiamine transmembrane transporter activity	Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.	got7fsn_ti	thiamine uptake transmembrane transporter activity|thiamin transmembrane transporter activity|thiamin permease activity|thiamin uptake transporter activity|vitamin B1 transporter activity|thiamine permease activity										GO:0015403|GO:0015402	RHEA:34919|Reactome:R-HSA-199626		molecular_function											owl:Class	
GO:0018310	biolink:NamedThing	protein-FMN linkage via S-(6-FMN)-L-cysteine	The formation of a protein-FMN linkage via S-(6-FMN)-L-cysteine.	got7fsn_ti												RESID:AA0220		biological_process											owl:Class	
GO:0043469	biolink:NamedThing	regulation of D-xylose catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose.	got7fsn_ti														biological_process											owl:Class	
GO:0043471	biolink:NamedThing	regulation of cellular carbohydrate catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:1990724	biolink:NamedThing	galectin complex	A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes.	got7fsn_ti	galectin-2 complex|galectin-1 complex				An example of this is Galectin-1 in human (P09382) in PMID:15476813 (inferred from physical interaction).		bhm	2015-04-07T15:03:15Z						cellular_component											owl:Class	
GO:0048254	biolink:NamedThing	snoRNA localization	Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.	got7fsn_ti	small nucleolar RNA localization|snoRNA localisation|establishment and maintenance of snoRNA localization													biological_process											owl:Class	
GO:0006403	biolink:NamedThing	RNA localization	A process in which RNA is transported to, or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of RNA localization|RNA localisation													biological_process											owl:Class	
GO:0022873	biolink:NamedThing	protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	maltose PTS transporter activity													molecular_function											owl:Class	
GO:0005363	biolink:NamedThing	maltose transmembrane transporter activity	Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch.	got7fsn_ti	maltose porter activity										GO:0015581	RHEA:33171		molecular_function											owl:Class	
GO:0005338	biolink:NamedThing	nucleotide-sugar transmembrane transporter activity	Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti											GO:0005339	Reactome:R-HSA-744230|Reactome:R-HSA-744231		molecular_function											owl:Class	
GO:0042138	biolink:NamedThing	meiotic DNA double-strand break formation	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.	got7fsn_ti														biological_process											owl:Class	
GO:0090305	biolink:NamedThing	nucleic acid phosphodiester bond hydrolysis	The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.	got7fsn_ti	nucleic acid cleavage						tb	2010-04-07T10:26:30Z						biological_process											owl:Class	
GO:0060199	biolink:NamedThing	clathrin-sculpted glutamate transport vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate.	got7fsn_ti	clathrin sculpted glutamate transport vesicle|clathrin sculpted glutamate constitutive secretory pathway transport vesicle													cellular_component											owl:Class	
GO:0080008	biolink:NamedThing	Cul4-RING E3 ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.	got7fsn_ti														cellular_component											owl:Class	
GO:0046893	biolink:NamedThing	iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation	The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase.	got7fsn_ti												RESID:AA0334		biological_process											owl:Class	
GO:0021743	biolink:NamedThing	hypoglossal nucleus development	The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0007379	biolink:NamedThing	segment specification	The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.	got7fsn_ti														biological_process											owl:Class	
GO:0033979	biolink:NamedThing	box H/ACA RNA metabolic process	The chemical reactions and pathways involving box H/ACA type small nucleolar RNA.	got7fsn_ti	box H/ACA sRNA metabolic process|box H/ACA snoRNA metabolic process	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0016074	biolink:NamedThing	sno(s)RNA metabolic process	The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA.	got7fsn_ti	box C/D sRNA metabolic process|snoRNA metabolism													biological_process											owl:Class	
GO:0007156	biolink:NamedThing	homophilic cell adhesion via plasma membrane adhesion molecules	The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.	got7fsn_ti														biological_process											owl:Class	
GO:0014076	biolink:NamedThing	response to fluoxetine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.	got7fsn_ti	response to selective serotonin reuptake inhibitor|response to SSRI				Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0036276	biolink:NamedThing	response to antidepressant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T02:12:44Z						biological_process											owl:Class	
GO:0106351	biolink:NamedThing	aspartate dehydrogenase NAD activity	Catalysis of the reaction: L-aspartate + H2O + NAD+ = oxaloacetate + NH3 + NADH+ H+.	got7fsn_ti							hjd	2021-01-20T17:39:50Z				RHEA:11788		molecular_function											owl:Class	
GO:0033735	biolink:NamedThing	aspartate dehydrogenase activity	Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+.	got7fsn_ti	L-aspartate:NAD(P)+ oxidoreductase (deaminating) activity|NADH2-dependent aspartate dehydrogenase activity|NADP+-dependent aspartate dehydrogenase activity|NAD-dependent aspartate dehydrogenase activity											MetaCyc:1.4.1.21-RXN|KEGG_REACTION:R07165|EC:1.4.1.21|KEGG_REACTION:R07164		molecular_function											owl:Class	
GO:0002501	biolink:NamedThing	peptide antigen assembly with MHC protein complex	The binding of a peptide to the antigen binding groove of an MHC protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0048688	biolink:NamedThing	negative regulation of sprouting of injured axon	Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon.	got7fsn_ti	down regulation of sprouting of injured axon|downregulation of sprouting of injured axon|down-regulation of sprouting of injured axon|inhibition of sprouting of injured axon													biological_process											owl:Class	
GO:0048681	biolink:NamedThing	negative regulation of axon regeneration	Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.	got7fsn_ti	downregulation of axon regeneration|down-regulation of axon regeneration|down regulation of axon regeneration|inhibition of axon regeneration													biological_process											owl:Class	
GO:0016781	biolink:NamedThing	phosphotransferase activity, paired acceptors	Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors.	got7fsn_ti												EC:2.7.9.-		molecular_function											owl:Class	
GO:0003421	biolink:NamedThing	growth plate cartilage axis specification	The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth.	got7fsn_ti	growth plate cartilage axis determination						dph	2009-12-22T09:16:33Z						biological_process											owl:Class	
GO:0044847	biolink:NamedThing	iron acquisition from host	The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell.	got7fsn_ti	acquisition by organism of nutrients from host via siderophores|iron acquisition|iron acquisition by symbiont from host heme|acquisition by symbiont of nutrients from host via siderophores|heme acquisition|iron acquisition by symbiont from host	https://github.com/geneontology/go-ontology/issues/17896					jl	2014-05-13T13:40:59Z			GO:0052099			biological_process											owl:Class	
GO:0044002	biolink:NamedThing	acquisition of nutrients from host	The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0016335	biolink:NamedThing	morphogenesis of larval imaginal disc epithelium	The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0044177	biolink:NamedThing	host cell Golgi apparatus	A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.	got7fsn_ti	host Golgi apparatus						jl	2009-09-04T03:14:38Z						cellular_component											owl:Class	
GO:0000947	biolink:NamedThing	amino acid catabolic process to alcohol via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.	got7fsn_ti														biological_process											owl:Class	
GO:0044632	biolink:NamedThing	negative regulation of complement activation, lectin pathway in other organism	Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism.	got7fsn_ti							jl	2012-07-05T01:18:43Z						biological_process											owl:Class	
GO:2000134	biolink:NamedThing	negative regulation of G1/S transition of mitotic cell cycle	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.	got7fsn_ti							mah	2010-09-29T09:38:51Z						biological_process											owl:Class	
GO:0031021	biolink:NamedThing	interphase microtubule organizing center	A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus.	got7fsn_ti	interphase microtubule organising center|iMTOC|interphase MTOC													cellular_component											owl:Class	
GO:0043060	biolink:NamedThing	meiotic metaphase I plate congression	The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I.	got7fsn_ti														biological_process											owl:Class	
GO:0036036	biolink:NamedThing	cardiac neural crest cell delamination	The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube.	got7fsn_ti							bf	2011-11-02T05:23:29Z						biological_process											owl:Class	
GO:0036032	biolink:NamedThing	neural crest cell delamination	The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.	got7fsn_ti	neural crest cell emigration|neural crest cell individualization|neural crest cell segregation						bf	2011-10-31T03:50:30Z						biological_process											owl:Class	
GO:0044377	biolink:NamedThing	RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	got7fsn_ti	RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending|RNA polymerase II proximal promoter region sequence-specific DNA binding, bending|RNA polymerase II promoter proximal region sequence-specific DNA binding, bending|RNA polymerase II proximal promoter sequence-specific DNA binding, bending						jl	2011-12-08T01:38:21Z						molecular_function											owl:Class	
GO:0044374	biolink:NamedThing	sequence-specific DNA binding, bending	The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	got7fsn_ti	DNA bending involving sequence-specific DNA binding						jl	2011-12-01T04:05:59Z						molecular_function											owl:Class	
GO:0052923	biolink:NamedThing	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity	Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate.	got7fsn_ti	SPP synthase activity|SPP-synthase activity|solPP synthase activity|nonaprenyl diphosphate synthase activity|solanesyl-diphosphate synthase activity|solanesyl diphosphate synthetase activity											MetaCyc:TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN|EC:2.5.1.84|RHEA:27563|KEGG_REACTION:R09250		molecular_function											owl:Class	
GO:0019884	biolink:NamedThing	antigen processing and presentation of exogenous antigen	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.	got7fsn_ti	antigen presentation, exogenous antigen													biological_process											owl:Class	
GO:0035867	biolink:NamedThing	alphav-beta3 integrin-IGF-1-IGF1R complex	A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.	got7fsn_ti							bf	2011-05-25T03:06:30Z						cellular_component											owl:Class	
GO:0043207	biolink:NamedThing	response to external biotic stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.	got7fsn_ti														biological_process											owl:Class	
GO:0061457	biolink:NamedThing	mesonephric cell migration involved in male gonad development	The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development.	got7fsn_ti							dph	2012-08-22T17:31:00Z						biological_process											owl:Class	
GO:0033425	biolink:NamedThing	CAU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CAU codon.	got7fsn_ti	histidine tRNA|CAT codon-amino acid adaptor activity				Note that in the standard genetic code, CAT codes for histidine.									molecular_function											owl:Class	
GO:0000482	biolink:NamedThing	maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0000481	biolink:NamedThing	maturation of 5S rRNA	Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0003122	biolink:NamedThing	norepinephrine-mediated vasodilation	A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings.	got7fsn_ti	regulation of vasodilation by circulating noradrenaline|regulation of vasodilation by circulating norepinephrine|regulation of vasodilation by neuronal norepinephrine|regulation of vasodilation by neuronal noradrenaline|regulation of vasodilation by norepinephrine|regulation of vasodilation by noradrenaline										GO:0003126|GO:0003125			biological_process											owl:Class	
GO:2000360	biolink:NamedThing	negative regulation of binding of sperm to zona pellucida	Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.	got7fsn_ti	negative regulation of ZPG binding						yaf	2011-02-03T02:42:54Z						biological_process											owl:Class	
GO:0031859	biolink:NamedThing	platelet activating factor receptor binding	Binding to a platelet activating factor receptor.	got7fsn_ti	platelet activating factor receptor ligand													molecular_function											owl:Class	
GO:0002228	biolink:NamedThing	natural killer cell mediated immunity	The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.	got7fsn_ti	NK cell mediated immunity													biological_process											owl:Class	
GO:0002449	biolink:NamedThing	lymphocyte mediated immunity	Any process involved in the carrying out of an immune response by a lymphocyte.	got7fsn_ti	cell-mediated immunity|cellular immune response													biological_process											owl:Class	
GO:0032357	biolink:NamedThing	oxidized purine DNA binding	Binding to a DNA region containing an oxidized purine residue.	got7fsn_ti	oxidized purine nucleobase DNA binding|oxidized purine base DNA binding|oxidised purine DNA binding													molecular_function											owl:Class	
GO:0030564	biolink:NamedThing	tRNA 2'-O-ribose methylation guide activity	Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0030561	biolink:NamedThing	RNA 2'-O-ribose methylation guide activity	Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0047012	biolink:NamedThing	sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity	Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one.	got7fsn_ti	3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity|3-beta-hydroxy-4-beta-methylcholestenoate dehydrogenase activity|3-beta-hydroxy-4-alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity|sterol 4-alpha-carboxylic decarboxylase activity|3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)											MetaCyc:1.1.1.170-RXN|EC:1.1.1.170		molecular_function											owl:Class	
GO:1990728	biolink:NamedThing	mitotic spindle assembly checkpoint MAD1-MAD2 complex	A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release from the MAD1-MAD2 complex.	got7fsn_ti	MAD1-MAD2 complex				An example of this is MAD1 in human (Q9Y6D9) in PMID:12006501 (inferred from physical interaction).		bhm	2015-04-15T10:14:17Z						cellular_component											owl:Class	
GO:0019938	biolink:NamedThing	peptide cross-linking via N6-(L-isoaspartyl)-L-lysine, presumed catalytic	The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; occurs in mammals in proteins as yet unidentified by a mechanism probably analogous to that of transglutaminase reactions.	got7fsn_ti											GO:0042266	RESID:AA0294		biological_process											owl:Class	
GO:0018420	biolink:NamedThing	peptide cross-linking via N6-(L-isoaspartyl)-L-lysine	The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues.	got7fsn_ti												RESID:AA0294		biological_process											owl:Class	
GO:0007299	biolink:NamedThing	ovarian follicle cell-cell adhesion	The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster.	got7fsn_ti	ovarian follicle cell adhesion|follicle cell adhesion													biological_process											owl:Class	
GO:0044501	biolink:NamedThing	modulation of signal transduction in other organism	The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism.	got7fsn_ti							jl	2012-02-23T03:48:19Z						biological_process											owl:Class	
GO:0047452	biolink:NamedThing	protoaphin-aglucone dehydratase (cyclizing) activity	Catalysis of the reaction: protoaphin aglucone = H(2)O + xanthoaphin.	got7fsn_ti	protoaphin dehydratase (cyclizing)|protoaphin dehydratase activity|protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)|protoaphin-aglucone hydro-lyase (cyclizing)											RHEA:23876|EC:4.2.1.73|MetaCyc:4.2.1.73-RXN|KEGG_REACTION:R03742		molecular_function											owl:Class	
GO:1903318	biolink:NamedThing	negative regulation of protein maturation	Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.	got7fsn_ti	down regulation of protein maturation|inhibition of protein maturation|downregulation of protein maturation|down-regulation of protein maturation						vw	2014-08-18T12:59:15Z						biological_process											owl:Class	
GO:0016934	biolink:NamedThing	extracellularly glycine-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	got7fsn_ti	glycine-inhibited chloride channel activity|glycine receptor|extracellular-glycine-gated chloride channel activity										GO:0004891	Reactome:R-HSA-975389		molecular_function											owl:Class	
GO:0016933	biolink:NamedThing	extracellularly glycine-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	got7fsn_ti	extracellular-glycine-gated ion channel activity|glycine receptor													molecular_function											owl:Class	
GO:0060071	biolink:NamedThing	Wnt signaling pathway, planar cell polarity pathway	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity.	got7fsn_ti	Wnt receptor signalling pathway, planar cell polarity pathway|Wnt receptor signaling pathway, planar cell polarity pathway|Wnt-JNK signaling pathway|non-canonical Wnt signaling pathway|Wnt-PCP signaling pathway|planar cell polarity pathway|Wnt-activated signaling pathway, planar cell polarity pathway|PCP pathway													biological_process											owl:Class	
GO:0035198	biolink:NamedThing	miRNA binding	Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.	got7fsn_ti	microRNA binding													molecular_function											owl:Class	
GO:1990931	biolink:NamedThing	mRNA N6-methyladenosine dioxygenase activity	Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde.	got7fsn_ti	RNA N6-methyladenosine dioxygenase activity|mRNA N(6)-methyladenine demethylase|mRNA N(6)-methyladenosine dioxygenase activity	https://github.com/geneontology/go-ontology/issues/21812					sp	2016-03-10T08:10:10Z				RHEA:49520|EC:1.14.11.53		molecular_function											owl:Class	
GO:0035515	biolink:NamedThing	oxidative RNA demethylase activity	Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.	got7fsn_ti	2-oxoglutarate-dependent RNA demethylase	https://github.com/geneontology/go-ontology/issues/21160					bf	2010-04-30T02:37:08Z				Reactome:R-HSA-8857692		molecular_function											owl:Class	
GO:0004905	biolink:NamedThing	type I interferon receptor activity	Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	interferon-delta receptor activity|type I IFN receptor activity|interferon-beta receptor activity|interferon-alpha/beta receptor activity|interferon-zeta receptor activity|interferon-alpha receptor activity|interferon-tau receptor activity|interferon-kappa receptor activity|interferon-omega receptor activity|interferon-epsilon receptor activity													molecular_function											owl:Class	
GO:0004904	biolink:NamedThing	interferon receptor activity	Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IFN receptor activity													molecular_function											owl:Class	
GO:0070900	biolink:NamedThing	mitochondrial tRNA modification	The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti							mah	2009-09-02T03:16:53Z						biological_process											owl:Class	
GO:0070525	biolink:NamedThing	tRNA threonylcarbamoyladenosine metabolic process	The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.	got7fsn_ti	t6A metabolism|threonylcarbamoyladenosine metabolism|t6A metabolic process													biological_process											owl:Class	
GO:0075016	biolink:NamedThing	appressorium formation	The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface.	got7fsn_ti	formation of an appressorium by symbiont on or near host|appressorium formation on or near host|appressorium formation for entry into host, on or near host													biological_process											owl:Class	
GO:0032600	biolink:NamedThing	chemokine receptor transport out of membrane raft	The directed movement of a chemokine receptor out of a membrane raft.	got7fsn_ti	chemokine receptor translocation out of membrane raft|chemokine receptor transport out of lipid raft													biological_process											owl:Class	
GO:0032599	biolink:NamedThing	protein transport out of membrane raft	The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	got7fsn_ti	protein translocation out of membrane raft|protein transport out of lipid raft|receptor transport out of membrane raft|receptor translocation out of membrane raft													biological_process											owl:Class	
GO:0072262	biolink:NamedThing	metanephric glomerular mesangial cell proliferation involved in metanephros development	The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population.	got7fsn_ti							mah	2010-03-30T02:27:27Z						biological_process											owl:Class	
GO:0072110	biolink:NamedThing	glomerular mesangial cell proliferation	The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population.	got7fsn_ti							mah	2010-02-22T10:45:47Z						biological_process											owl:Class	
GO:0070975	biolink:NamedThing	FHA domain binding	Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.	got7fsn_ti	Forkhead-associated domain binding						mah	2009-10-02T01:09:20Z						molecular_function											owl:Class	
GO:0004779	biolink:NamedThing	sulfate adenylyltransferase activity	Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate.	got7fsn_ti	sulphate adenylyltransferase activity													molecular_function											owl:Class	
GO:0006526	biolink:NamedThing	arginine biosynthetic process	The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.	got7fsn_ti	arginine anabolism|arginine formation|arginine biosynthesis|arginine synthesis											MetaCyc:ARGSYN-PWY|MetaCyc:ARGININE-SYN4-PWY|MetaCyc:ARGSYNBSUB-PWY		biological_process											owl:Class	
GO:0009084	biolink:NamedThing	glutamine family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.	got7fsn_ti	glutamine family amino acid formation|glutamine family amino acid biosynthesis|glutamine family amino acid synthesis|glutamine family amino acid anabolism													biological_process											owl:Class	
GO:0035599	biolink:NamedThing	aspartic acid methylthiotransferase activity	Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid.	got7fsn_ti					Note that peptidyl-L-beta-methylthioaspartic acid is typical of bacterial ribosomal protein S12.		bf	2010-11-12T01:31:23Z				RESID:AA0232		molecular_function											owl:Class	
GO:0045334	biolink:NamedThing	clathrin-coated endocytic vesicle	A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.	got7fsn_ti												NIF_Subcellular:sao1243595998		cellular_component											owl:Class	
GO:0018117	biolink:NamedThing	protein adenylylation	The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid.	got7fsn_ti	protein adenylation|protein AMPylation|protein amino acid adenylylation										GO:0018176			biological_process											owl:Class	
GO:0030692	biolink:NamedThing	Noc4p-Nop14p complex	A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis.	got7fsn_ti	Nop7 complex|Nop7 subcomplex				Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654' and/or 'nuclear pore ; GO:0005643'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.									cellular_component											owl:Class	
GO:0030689	biolink:NamedThing	Noc complex	Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis.	got7fsn_ti					Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the definition uses Saccharomyces gene product names because this complex has only been described in Saccharomyces cerevisiae and no other names have yet arisen; the term nevertheless can be used for analogous complexes in other eukaryotes, and the definition can be changed if better wording is found.									cellular_component											owl:Class	
GO:0071456	biolink:NamedThing	cellular response to hypoxia	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	got7fsn_ti	cellular response to lowered oxygen tension|cellular response to hypoxic stress				Note that this term should not be confused with 'cellular response to anoxia ; GO:0071454'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.		mah	2009-12-16T04:45:20Z						biological_process											owl:Class	
GO:0102865	biolink:NamedThing	delta6-acyl-lipid desaturase activity	Catalysis of the reaction: a gamma-linolenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O(2) + 2 H(+) <=> a (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H(2)O.	got7fsn_ti												MetaCyc:RXN-8343|EC:1.14.19.38|RHEA:46536		molecular_function											owl:Class	
GO:0019498	biolink:NamedThing	n-octane oxidation	The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA.	got7fsn_ti												MetaCyc:P221-PWY		biological_process											owl:Class	
GO:0018939	biolink:NamedThing	n-octane metabolic process	The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System.	got7fsn_ti	n-octane metabolism											UM-BBD_pathwayID:oct		biological_process											owl:Class	
GO:0030926	biolink:NamedThing	calcium incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide	The incorporation of calcium into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site.	got7fsn_ti												RESID:AA0366		biological_process											owl:Class	
GO:0030925	biolink:NamedThing	calcium incorporation into metallo-oxygen cluster	The incorporation of calcium into a metallo-oxygen cluster.	got7fsn_ti														biological_process											owl:Class	
GO:0043773	biolink:NamedThing	coenzyme F420-0 gamma-glutamyl ligase activity	Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates.	got7fsn_ti	F420-0 gamma-glutamyl ligase activity													molecular_function											owl:Class	
GO:0039628	biolink:NamedThing	T=169 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=169 symmetry. T=169 icosahedral capsid is composed of 12 pentameric and 1680 hexameric capsomeres for a total of 10140 capsid proteins.	got7fsn_ti	T=169 icosahedral capsid						bf	2012-08-03T16:27:55Z						cellular_component											owl:Class	
GO:0140622	biolink:NamedThing	ER-to-endosome phospholipid transfer complex	Lipid transfer complex that is responsible for the non-vesicular transport of phospholipids, such as phosphatidylserine, from the endoplasmic reticulum to the endosome. It resides in the endosomal (acceptor) membrane and binds to specific lipids on the donor membrane at the ER-endosome contact site.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15338					pg	2021-03-10T11:27:24Z						cellular_component											owl:Class	
GO:0098796	biolink:NamedThing	membrane protein complex	Any protein complex that is part of a membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0036119	biolink:NamedThing	response to platelet-derived growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.	got7fsn_ti	response to platelet-derived growth factor stimulus|response to PDGF stimulus						bf	2012-02-20T02:48:00Z						biological_process											owl:Class	
GO:0007135	biolink:NamedThing	meiosis II	The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.	got7fsn_ti	meiosis II nuclear division											Wikipedia:Meiosis#Meiosis_II		biological_process											owl:Class	
GO:0140013	biolink:NamedThing	meiotic nuclear division	One of the two nuclear divisions that occur as part of the meiotic cell cycle.	got7fsn_ti	meiosis	https://github.com/geneontology/go-ontology/issues/19910					pg	2017-03-23T09:40:00Z						biological_process											owl:Class	
GO:0038178	biolink:NamedThing	complement component C5a signaling pathway	A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.	got7fsn_ti	complement component C5a-induced signaling pathway						bf	2012-09-21T10:55:00Z						biological_process											owl:Class	
GO:0061327	biolink:NamedThing	anterior Malpighian tubule development	The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.	got7fsn_ti							dph	2010-09-28T01:23:18Z						biological_process											owl:Class	
GO:0140425	biolink:NamedThing	galactose import across plasma membrane	The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18788					pg	2020-02-10T08:46:09Z						biological_process											owl:Class	
GO:0021536	biolink:NamedThing	diencephalon development	The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0000900	biolink:NamedThing	translation repressor activity, mRNA regulatory element binding	Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.	got7fsn_ti	translation repressor activity, nucleic acid binding	https://github.com/geneontology/go-ontology/issues/15049												molecular_function											owl:Class	
GO:0030371	biolink:NamedThing	translation repressor activity	Antagonizes ribosome-mediated translation of mRNA into a polypeptide.	got7fsn_ti														molecular_function											owl:Class	
GO:0032039	biolink:NamedThing	integrator complex	A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15979												cellular_component											owl:Class	
GO:0004698	biolink:NamedThing	calcium-dependent protein kinase C activity	Calcium-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	got7fsn_ti	calcium-dependent PKC activity|conventional protein kinase C activity				This reaction requires diacylglycerol and calcium.							Reactome:R-HSA-114684|Reactome:R-HSA-114683|Reactome:R-HSA-421007|Reactome:R-HSA-416639|EC:2.7.11.13		molecular_function											owl:Class	
GO:0048344	biolink:NamedThing	paraxial mesodermal cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0010198	biolink:NamedThing	synergid death	Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.	got7fsn_ti	synergid degeneration|synergid cell death										GO:0048470			biological_process											owl:Class	
GO:0051270	biolink:NamedThing	regulation of cellular component movement	Any process that modulates the frequency, rate or extent of the movement of a cellular component.	got7fsn_ti	regulation of cellular component motion|regulation of cell movement													biological_process											owl:Class	
GO:0005462	biolink:NamedThing	UDP-N-acetylglucosamine transmembrane transporter activity	Enables the transfer of a UDP-N-acetylglucosamine from one side of a membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti												Reactome:R-HSA-741450|Reactome:R-HSA-742354|Reactome:R-HSA-5653622		molecular_function											owl:Class	
GO:0004115	biolink:NamedThing	3',5'-cyclic-AMP phosphodiesterase activity	Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate.	got7fsn_ti	3',5'-cyclic-AMP-specific phosphodiesterase activity|3',5' cAMP-specific phosphodiesterase activity|cyclic AMP-specific phosphodiesterase activity|cAMP-specific phosphodiesterase activity|adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity|3',5'-cAMP-specific phosphodiesterase activity											Reactome:R-HSA-9644869|MetaCyc:RXN0-5038|RHEA:25277|EC:3.1.4.53|Reactome:R-HSA-9629675|Reactome:R-HSA-111962|Reactome:R-HSA-9705507|Reactome:R-HSA-418553		molecular_function											owl:Class	
GO:1990170	biolink:NamedThing	stress response to cadmium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus.	got7fsn_ti	stress response to cadmium|response to cadmium toxicity|response to cadmium ion stress						pr	2013-08-14T12:55:45Z						biological_process											owl:Class	
GO:0046686	biolink:NamedThing	response to cadmium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	got7fsn_ti	response to cadmium|cadmium sensitivity/resistance													biological_process											owl:Class	
GO:0033275	biolink:NamedThing	actin-myosin filament sliding	The sliding movement of actin thin filaments and myosin thick filaments past each other.	got7fsn_ti	actin filament sliding													biological_process											owl:Class	
GO:0070252	biolink:NamedThing	actin-mediated cell contraction	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.	got7fsn_ti														biological_process											owl:Class	
GO:1990074	biolink:NamedThing	polyuridylation-dependent mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20568					tb	2013-04-16T22:51:46Z						biological_process											owl:Class	
GO:0043632	biolink:NamedThing	modification-dependent macromolecule catabolic process	The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0021662	biolink:NamedThing	rhombomere 4 structural organization	The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti	rhombomere 4 structural organisation													biological_process											owl:Class	
GO:0031839	biolink:NamedThing	type 1 neuromedin U receptor binding	Binding to a type 1 neuromedin U receptor.	got7fsn_ti	type 1 neuromedin U receptor ligand													molecular_function											owl:Class	
GO:0000954	biolink:NamedThing	methionine catabolic process to 3-methylthiopropanoate	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.	got7fsn_ti														biological_process											owl:Class	
GO:0000948	biolink:NamedThing	amino acid catabolic process to carboxylic acid via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.	got7fsn_ti														biological_process											owl:Class	
GO:0070205	biolink:NamedThing	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity	Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.	got7fsn_ti	6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity|MenH|SHCHC synthase activity|YfbB|2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity											EC:4.2.99.20|RHEA:25597|KEGG_REACTION:R08166|MetaCyc:RXN-9310		molecular_function											owl:Class	
GO:0016835	biolink:NamedThing	carbon-oxygen lyase activity	Catalysis of the breakage of a carbon-oxygen bond.	got7fsn_ti	other carbon-oxygen lyase activity											EC:4.2.-.-		molecular_function											owl:Class	
GO:0034178	biolink:NamedThing	toll-like receptor 13 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 13.	got7fsn_ti	toll-like receptor 13 signalling pathway|TLR13 signaling pathway													biological_process											owl:Class	
GO:0051302	biolink:NamedThing	regulation of cell division	Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.	got7fsn_ti														biological_process											owl:Class	
GO:0007197	biolink:NamedThing	adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	got7fsn_ti	muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway|muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway|inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signalling pathway|inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway													biological_process											owl:Class	
GO:0047599	biolink:NamedThing	8-oxocoformycin reductase activity	Catalysis of the reaction: coformycin + NADP(+) = 8-oxocoformycin + 2 H(+) + NADPH.	got7fsn_ti	coformycin:NADP+ 8-oxidoreductase activity|8-ketodeoxycoformycin reductase activity											RHEA:23168|EC:1.1.1.235|MetaCyc:8-OXOCOFORMYCIN-REDUCTASE-RXN|KEGG_REACTION:R03667		molecular_function											owl:Class	
GO:0018708	biolink:NamedThing	thiol S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.	got7fsn_ti	S-adenosyl-L-methionine:thiol S-methyltransferase activity|TMT|thiol methyltransferase activity											RHEA:18277|MetaCyc:THIOL-S-METHYLTRANSFERASE-RXN|UM-BBD_enzymeID:e0146|Reactome:R-HSA-175976|EC:2.1.1.9		molecular_function											owl:Class	
GO:0030501	biolink:NamedThing	positive regulation of bone mineralization	Any process that activates or increases the frequency, rate or extent of bone mineralization.	got7fsn_ti	stimulation of bone mineralization|up regulation of bone mineralization|activation of bone mineralization|up-regulation of bone mineralization|upregulation of bone mineralization													biological_process											owl:Class	
GO:0071346	biolink:NamedThing	cellular response to interferon-gamma	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.	got7fsn_ti	cellular response to type II interferon|cellular response to immune interferon|cellular response to gamma-interferon|cellular response to type II IFN						mah	2009-12-11T02:48:00Z						biological_process											owl:Class	
GO:0001825	biolink:NamedThing	blastocyst formation	The initial formation of a blastocyst from a solid ball of cells known as a morula.	got7fsn_ti					See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'.									biological_process											owl:Class	
GO:0071938	biolink:NamedThing	vitamin A transport	The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.	got7fsn_ti	vitamin A uptake and transport						mah	2010-09-30T04:15:10Z						biological_process											owl:Class	
GO:0051180	biolink:NamedThing	vitamin transport	The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	got7fsn_ti	vitamin or cofactor transport													biological_process											owl:Class	
GO:0009989	biolink:NamedThing	cell-matrix recognition	Cell recognition that involves the interaction of the cell with the extracellular matrix.	got7fsn_ti														biological_process											owl:Class	
GO:0008037	biolink:NamedThing	cell recognition	The process in which a cell in an organism interprets its surroundings.	got7fsn_ti	recognition of surroundings by cell													biological_process											owl:Class	
GO:1990715	biolink:NamedThing	mRNA CDS binding	Binding to an mRNA molecule coding sequence (CDS).	got7fsn_ti	mRNA coding region binding|mRNA coding sequence binding						kmv	2015-03-27T20:59:49Z						molecular_function											owl:Class	
GO:0046159	biolink:NamedThing	ocellus pigment catabolic process	The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.	got7fsn_ti	ocellus pigment degradation|ocellus pigment catabolism|ocellus pigment breakdown													biological_process											owl:Class	
GO:0046149	biolink:NamedThing	pigment catabolic process	The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.	got7fsn_ti	pigment degradation|pigment breakdown|pigment catabolism													biological_process											owl:Class	
GO:0030849	biolink:NamedThing	autosome	Any chromosome other than a sex chromosome.	got7fsn_ti					Note that this term is mainly relevant in organisms that have both sex chromosomes and non-sex-determining chromosomes in an individual organism.							Wikipedia:Autosome		cellular_component											owl:Class	
GO:0005694	biolink:NamedThing	chromosome	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.	got7fsn_ti	prophase chromosome|chromatid|interphase chromosome				Chromosomes include parts that are not part of the chromatin.  Examples include the kinetochore.							Wikipedia:Chromosome		cellular_component											owl:Class	
GO:0090189	biolink:NamedThing	regulation of branching involved in ureteric bud morphogenesis	Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	got7fsn_ti							tb	2009-12-18T11:11:17Z						biological_process											owl:Class	
GO:0006932	biolink:NamedThing	substrate-dependent cell migration, cell contraction	The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves.	got7fsn_ti	substrate-bound cell migration, cell contraction													biological_process											owl:Class	
GO:0060327	biolink:NamedThing	cytoplasmic actin-based contraction involved in cell motility	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.	got7fsn_ti														biological_process											owl:Class	
GO:0050653	biolink:NamedThing	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.	got7fsn_ti	chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|chondroitin sulfate proteoglycan synthesis, polysaccharide chain synthesis|chondroitin sulfate proteoglycan chain elongation|chondroitin sulfate proteoglycan formation, polysaccharide chain biosynthesis|chondroitin sulfate proteoglycan formation, polysaccharide chain formation|chondroitin sulfate proteoglycan anabolism, polysaccharide chain anabolism|chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis													biological_process											owl:Class	
GO:0002778	biolink:NamedThing	antibacterial peptide production	The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0002775	biolink:NamedThing	antimicrobial peptide production	The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0030225	biolink:NamedThing	macrophage differentiation	The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.	got7fsn_ti	macrophage cell differentiation													biological_process											owl:Class	
GO:0002573	biolink:NamedThing	myeloid leukocyte differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.	got7fsn_ti	myeloid leucocyte differentiation													biological_process											owl:Class	
GO:0018079	biolink:NamedThing	protein halogenation	The addition of a halogen to a protein amino acid.	got7fsn_ti	protein amino acid halogenation													biological_process											owl:Class	
GO:0018083	biolink:NamedThing	peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine	The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases.	got7fsn_ti	peptidyl-L-3-oxoalanine anabolism from peptidyl-cysteine or peptidyl-serine|peptidyl-L-3-oxoalanine formation from peptidyl-cysteine or peptidyl-serine|peptidyl-L-3-oxoalanine synthesis from peptidyl-cysteine or peptidyl-serine											RESID:AA0185		biological_process											owl:Class	
GO:0047569	biolink:NamedThing	3-oxoadipate CoA-transferase activity	Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.	got7fsn_ti	3-oxoadipate succinyl-CoA transferase activity|beta-ketoadipate:succinyl-CoA transferase activity|succinyl-CoA:3-oxoadipate CoA-transferase activity|3-oxoadipate coenzyme A-transferase activity											RHEA:12048|EC:2.8.3.6|UM-BBD_reactionID:r1050|MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN		molecular_function											owl:Class	
GO:0050237	biolink:NamedThing	pyridoxine 4-oxidase activity	Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2.	got7fsn_ti	pyridoxin 4-oxidase activity|pyridoxine:oxygen 4-oxidoreductase activity|pyridoxol 4-oxidase activity											MetaCyc:PYRIDOXINE-4-OXIDASE-RXN|RHEA:15033|EC:1.1.3.12		molecular_function											owl:Class	
GO:0072136	biolink:NamedThing	metanephric mesenchymal cell proliferation involved in metanephros development	The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population.	got7fsn_ti							mah	2010-02-22T02:34:56Z						biological_process											owl:Class	
GO:0072203	biolink:NamedThing	cell proliferation involved in metanephros development	The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros.	got7fsn_ti							mah	2010-03-18T10:42:27Z						biological_process											owl:Class	
GO:0072113	biolink:NamedThing	head kidney development	The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.	got7fsn_ti							mah	2010-02-22T11:09:38Z						biological_process											owl:Class	
GO:0048534	biolink:NamedThing	hematopoietic or lymphoid organ development	The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.	got7fsn_ti	hemopoietic or lymphoid organ development|haemopoietic or lymphoid organ development|haematopoietic or lymphoid organ development													biological_process											owl:Class	
GO:0030791	biolink:NamedThing	arsenite methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.	got7fsn_ti	S-adenosyl-L-methionine:methylarsonite As-methyltransferase activity|S-adenosyl-L-methionine:arsenite As-methyltransferase activity|S-adenosyl-L-methionine:arsenic(III) methyltransferase activity				Note that the enzyme arsenite methyltransferase also has methylarsonite methyltransferase activity (GO:0030792).							Reactome:R-HSA-5696213|EC:2.1.1.137|Reactome:R-HSA-5696220|RHEA:15293|UM-BBD_reactionID:r0805|MetaCyc:2.1.1.137-RXN		molecular_function											owl:Class	
GO:0038085	biolink:NamedThing	vascular endothelial growth factor binding	Binding to a vascular endothelial growth factor.	got7fsn_ti	VEGF binding						bf	2012-02-01T02:36:36Z						molecular_function											owl:Class	
GO:0036358	biolink:NamedThing	lipoteichoic acid D-alanylation	The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA).	got7fsn_ti	D-alanyl lipoteichoic acid formation|D-alanyl LTA formation|LTA D-alanylation						bf	2012-09-19T15:09:05Z						biological_process											owl:Class	
GO:0070400	biolink:NamedThing	teichoic acid D-alanylation	The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid.	got7fsn_ti	teichoic acid alanylation													biological_process											owl:Class	
GO:0001565	biolink:NamedThing	phorbol ester receptor activity	Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0070094	biolink:NamedThing	positive regulation of glucagon secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.	got7fsn_ti	activation of glucagon secretion|up-regulation of glucagon secretion|upregulation of glucagon secretion|stimulation of glucagon secretion|up regulation of glucagon secretion													biological_process											owl:Class	
GO:0070092	biolink:NamedThing	regulation of glucagon secretion	Any process that modulates the frequency, rate or extent of the regulated release of glucagon.	got7fsn_ti														biological_process											owl:Class	
GO:0035917	biolink:NamedThing	negative regulation of calcium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism.	got7fsn_ti	inhibition of calcium channel activity in other organism|downregulation of calcium channel activity in other organism|down-regulation of calcium channel activity in other organism						bf	2011-07-01T11:52:55Z						biological_process											owl:Class	
GO:0031203	biolink:NamedThing	posttranslational protein targeting to membrane, docking	The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex.	got7fsn_ti	posttranslational protein membrane targeting, docking|Sec-translated protein complex assembly|protein docking during posttranslational protein targeting to membrane													biological_process											owl:Class	
GO:0097503	biolink:NamedThing	sialylation	The covalent attachment of sialic acid to a substrate molecule.	got7fsn_ti							pr	2013-09-20T09:53:10Z						biological_process											owl:Class	
GO:0043374	biolink:NamedThing	CD8-positive, alpha-beta T cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.	got7fsn_ti	CD8-positive, alpha-beta T-cell differentiation|CD8-positive, alpha-beta T-lymphocyte differentiation|CD8-positive, alpha-beta T lymphocyte differentiation|CD8-positive, alpha-beta T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0051555	biolink:NamedThing	flavonol biosynthetic process	The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.	got7fsn_ti												MetaCyc:PWY-3101		biological_process											owl:Class	
GO:0051553	biolink:NamedThing	flavone biosynthetic process	The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).	got7fsn_ti	2-phenylchromone biosynthetic process|2-phenyl-4H-1-benzopyran-4-one biosynthetic process|2-phenyl-4H-1-benzopyran-4-one biosynthesis|2-phenylchromone biosynthesis													biological_process											owl:Class	
GO:0015467	biolink:NamedThing	G-protein activated inward rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.	got7fsn_ti	G-protein-activated inward rectifier potassium channel activity|G protein activated inward rectifier potassium channel activity|G-protein enhanced inward rectifier potassium channel activity|G protein enhanced inward rectifier potassium channel activity|G-protein-enhanced inward rectifier potassium channel activity										GO:0015273	Reactome:R-HSA-1013020		molecular_function											owl:Class	
GO:0005242	biolink:NamedThing	inward rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.	got7fsn_ti	Kir channel activity											Reactome:R-HSA-1296046|Reactome:R-HSA-1296045|Reactome:R-HSA-5678261|Reactome:R-HSA-5678418|Reactome:R-HSA-1369017		molecular_function											owl:Class	
GO:1990727	biolink:NamedThing	tubulin folding cofactor complex	A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur.	got7fsn_ti							pr	2015-04-08T10:29:43Z						cellular_component											owl:Class	
GO:0098542	biolink:NamedThing	defense response to other organism	Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.	got7fsn_ti	defence response to pathogen, incompatible interaction|resistance response to pathogen|defense response, incompatible interaction|defence response incompatible interaction	https://github.com/geneontology/go-ontology/issues/18737					dos	2013-11-11T12:59:11Z			GO:0009814			biological_process											owl:Class	
GO:0000700	biolink:NamedThing	mismatch base pair DNA N-glycosylase activity	Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.	got7fsn_ti														molecular_function											owl:Class	
GO:0001183	biolink:NamedThing	transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I promoter for the nuclear large ribosomal RNA (rRNA) transcript by the addition of ribonucleotides catalyzed by RNA polymerase I.	got7fsn_ti							krc	2011-08-15T03:57:25Z						biological_process											owl:Class	
GO:0006362	biolink:NamedThing	transcription elongation from RNA polymerase I promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.	got7fsn_ti	RNA elongation from Pol I promoter|RNA polymerase I transcription elongation factor activity													biological_process											owl:Class	
GO:0010587	biolink:NamedThing	miRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.	got7fsn_ti	microRNA catabolic process													biological_process											owl:Class	
GO:0052839	biolink:NamedThing	inositol diphosphate tetrakisphosphate kinase activity	Catalysis of the reaction: Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate.	got7fsn_ti							ai	2011-11-29T04:14:22Z				Reactome:R-HSA-1855230|Reactome:R-HSA-1855193		molecular_function											owl:Class	
GO:0044618	biolink:NamedThing	modulation of relaxation of uterine smooth muscle in other organism	The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism.	got7fsn_ti	regulation of relaxation of uterine smooth muscle in other organism						jl	2012-07-04T01:56:04Z						biological_process											owl:Class	
GO:0044617	biolink:NamedThing	modulation of relaxation of smooth muscle in other organism	The process in which an organism effects a change in the relaxation of smooth muscle in a second organism.	got7fsn_ti	regulation of relaxation of smooth muscle in other organism						jl	2012-07-04T01:55:37Z						biological_process											owl:Class	
GO:0031979	biolink:NamedThing	plasma membrane-derived thylakoid lumen	The volume enclosed by a plasma membrane-derived thylakoid.	got7fsn_ti	plasma membrane thylakoid lumen													cellular_component											owl:Class	
GO:1990793	biolink:NamedThing	substance P secretion, neurotransmission	The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter.	got7fsn_ti							sl	2015-07-09T19:43:36Z						biological_process											owl:Class	
GO:1990772	biolink:NamedThing	substance P secretion	The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity.	got7fsn_ti							sl	2015-06-15T18:17:30Z						biological_process											owl:Class	
GO:1902738	biolink:NamedThing	regulation of chondrocyte differentiation involved in endochondral bone morphogenesis	Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti							mr	2014-02-26T15:36:15Z						biological_process											owl:Class	
GO:0018408	biolink:NamedThing	peptidyl-thyronine iodination to form 3',3'',5',5''-tetraiodo-L-thyronine	The iodination of peptidyl-thyronine to form peptidyl-3',3'',5',5''-tetraiodo-L-thyronine (L-thyroxine).	got7fsn_ti												RESID:AA0178		biological_process											owl:Class	
GO:0018078	biolink:NamedThing	peptidyl-thyronine iodination	The iodination of peptidyl-thyronine, formed from tyrosine.	got7fsn_ti												RESID:AA0178|RESID:AA0177		biological_process											owl:Class	
GO:0098633	biolink:NamedThing	collagen fibril binding	Binding to a collagen fibril.	got7fsn_ti														molecular_function											owl:Class	
GO:0070848	biolink:NamedThing	response to growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	got7fsn_ti	response to growth factor stimulus						mah	2009-08-04T04:24:18Z						biological_process											owl:Class	
GO:0072552	biolink:NamedThing	monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity	Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O.	got7fsn_ti							mah	2011-01-25T03:15:31Z						molecular_function											owl:Class	
GO:0052814	biolink:NamedThing	medium-chain-aldehyde dehydrogenase activity	Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons.	got7fsn_ti	medium-chain-aldehyde:NAD+ oxidoreductase activity|medium-chain aliphatic aldehyde dehydrogenase activity|medium-chain fatty aldehyde dehydrogenase activity							2011-10-25T03:04:41Z				EC:1.2.1.-		molecular_function											owl:Class	
GO:0061607	biolink:NamedThing	peptide alpha-N-propionyltransferase activity	Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein.	got7fsn_ti	N-terminal propionyltransferase activity						dph	2014-02-11T14:24:35Z						molecular_function											owl:Class	
GO:0071081	biolink:NamedThing	alpha3-beta1 integrin-CD63 complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63.	got7fsn_ti	ITGA3-ITGB1-CD63 complex						mah	2009-11-06T04:43:43Z						cellular_component											owl:Class	
GO:0000751	biolink:NamedThing	mitotic cell cycle G1 arrest in response to pheromone	The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	cell cycle arrest in response to pheromone										GO:0030571			biological_process											owl:Class	
GO:0045930	biolink:NamedThing	negative regulation of mitotic cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.	got7fsn_ti	inhibition of progression through mitotic cell cycle|down-regulation of progression through mitotic cell cycle|down regulation of progression through mitotic cell cycle|negative regulation of progression through mitotic cell cycle|negative regulation of mitotic cell cycle progression|downregulation of progression through mitotic cell cycle													biological_process											owl:Class	
GO:0048045	biolink:NamedThing	trans-pentaprenyltranstransferase activity	Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + diphosphate.	got7fsn_ti	all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase activity|hexaprenyl diphosphate synthase activity|all-trans-hexaprenyl-diphosphate synthase activity|hexaprenyl pyrophosphate synthetase activity											KEGG_REACTION:R05613|RHEA:22632		molecular_function											owl:Class	
GO:0071127	biolink:NamedThing	alpha9-beta1 integrin-osteopontin complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin.	got7fsn_ti	ITGA9-ITGB1-SPP1 complex						mah	2009-11-13T02:24:09Z						cellular_component											owl:Class	
GO:0051062	biolink:NamedThing	UDP reductase activity	Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.	got7fsn_ti	UDP reduction											RHEA:28026|MetaCyc:UDPREDUCT-RXN		molecular_function											owl:Class	
GO:0090659	biolink:NamedThing	walking behavior	The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.	got7fsn_ti	locomotor gait pattern						tb	2015-08-27T16:34:28Z						biological_process											owl:Class	
GO:0008818	biolink:NamedThing	cobalamin 5'-phosphate synthase activity	Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP.	got7fsn_ti												RHEA:23560|MetaCyc:COBALAMIN5PSYN-RXN		molecular_function											owl:Class	
GO:0033426	biolink:NamedThing	CAC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CAC codon.	got7fsn_ti	histidine tRNA				Note that in the standard genetic code, CAC codes for histidine.									molecular_function											owl:Class	
GO:0050881	biolink:NamedThing	musculoskeletal movement	The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.	got7fsn_ti														biological_process											owl:Class	
GO:0050905	biolink:NamedThing	neuromuscular process	Any process pertaining to the functions of the nervous and muscular systems of an organism.	got7fsn_ti	neuromotor process|neuromuscular physiological process													biological_process											owl:Class	
GO:0030130	biolink:NamedThing	clathrin coat of trans-Golgi network vesicle	A clathrin coat found on a vesicle of the trans-Golgi network.	got7fsn_ti	clathrin coat of TGN vesicle													cellular_component											owl:Class	
GO:0075342	biolink:NamedThing	disruption by symbiont of host cell PML body	The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	disassembly by symbiont of host cell PML NB|degradation by symbiont of host cell PML body|disassembly by symbiont of host cell PML nuclear body|catabolism by symbiont of host cell PML body|disassembly by symbiont of host cell PML body|disassembly by symbiont of host cell PML body during symbiotic interaction													biological_process											owl:Class	
GO:0018759	biolink:NamedThing	methenyltetrahydromethanopterin cyclohydrolase activity	Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+).	got7fsn_ti	5,10-methenyltetrahydromethanopterin cyclohydrolase activity|5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing)|N5,N10-methenyltetrahydromethanopterin cyclohydrolase activity|methenyl-H4MPT cyclohydrolase activity|methenyl-H(4)MPT cyclohydrolase activity											EC:3.5.4.27|KEGG_REACTION:R03464|UM-BBD_reactionID:r0347|MetaCyc:3.5.4.27-RXN|RHEA:19053		molecular_function											owl:Class	
GO:1990414	biolink:NamedThing	replication-born double-strand break repair via sister chromatid exchange	The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.	got7fsn_ti	replication-born DSB repair by SCE						rb	2014-07-10T21:20:34Z						biological_process											owl:Class	
GO:0000724	biolink:NamedThing	double-strand break repair via homologous recombination	The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.	got7fsn_ti	homologous recombinational repair|homology-directed repair|HDR|HRR|Rhp51-dependent recombinational repair|Rad51-dependent recombinational repair										GO:0016924			biological_process											owl:Class	
GO:0048190	biolink:NamedThing	wing disc dorsal/ventral pattern formation	The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.	got7fsn_ti	wing disc dorsal-ventral pattern formation|wing disc dorsoventral pattern formation													biological_process											owl:Class	
GO:0035222	biolink:NamedThing	wing disc pattern formation	The process giving rise to the pattern of cell differentiation in the wing imaginal disc.	got7fsn_ti														biological_process											owl:Class	
GO:0018697	biolink:NamedThing	carbonyl sulfide nitrogenase activity	Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide.	got7fsn_ti	carbonyl sulphide nitrogenase activity											EC:1.18.6.1|UM-BBD_reactionID:r0600		molecular_function											owl:Class	
GO:0043076	biolink:NamedThing	megasporocyte nucleus	The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents.	got7fsn_ti	megaspore mother cell nucleus													cellular_component											owl:Class	
GO:0005634	biolink:NamedThing	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	got7fsn_ti	horsetail nucleus|cell nucleus											Wikipedia:Cell_nucleus|NIF_Subcellular:sao1702920020		cellular_component											owl:Class	
GO:1990689	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane	The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.	got7fsn_ti	ERGIC-derived vesicle fusion with cis-Golgi cisterna membrane|endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with cis-Golgi cisterna membrane|ERGIC-derived vesicle fusion with Golgi cis cisterna membrane|ER-Golgi intermediate compartment derived vesicle fusion with cis-Golgi cisterna membrane|ER-Golgi intermediate compartment derived vesicle fusion with Golgi cis cisterna membrane						bhm	2015-03-12T09:41:48Z						biological_process											owl:Class	
GO:1990670	biolink:NamedThing	vesicle fusion with Golgi cis cisterna membrane	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.	got7fsn_ti							bhm	2015-03-02T11:25:19Z						biological_process											owl:Class	
GO:0023028	biolink:NamedThing	MHC class I protein binding, via lateral surface	Binding to a major histocompatibility complex class I molecules via the lateral surface.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0042288	biolink:NamedThing	MHC class I protein binding	Binding to a major histocompatibility complex class I molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.	got7fsn_ti	major histocompatibility complex class I ligand|T cell receptor activity|major histocompatibility complex class I binding|gamma-delta T cell receptor activity|alpha-beta T cell receptor activity				Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children.									molecular_function											owl:Class	
GO:0071202	biolink:NamedThing	Kv4.3-DPP10 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.	got7fsn_ti	Kv4.3-DPPY channel complex						mah	2009-11-23T05:21:37Z				CORUM:598		cellular_component											owl:Class	
GO:0047938	biolink:NamedThing	glucose-6-phosphate 1-epimerase activity	Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.	got7fsn_ti	D-glucose-6-phosphate 1-epimerase activity|glucose-6 phosphate 1-epimerase activity											RHEA:16249|MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN|EC:5.1.3.15		molecular_function											owl:Class	
GO:0052878	biolink:NamedThing	linoleate 8R-lipoxygenase activity	Catalysis of the reaction: O(2) + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate.	got7fsn_ti	5,8-linoleate diol synthase (bifunctional enzyme) activity|7,8-LDS (bifunctional enzyme) activity|7,8-linoleate diol synthase (bifunctional enzyme) activity|5,8-LDS (bifunctional enzyme) activity|linoleate diol synthase activity											MetaCyc:1.13.11.44-RXN|KEGG_REACTION:R07061|EC:1.13.11.60|RHEA:25395		molecular_function											owl:Class	
GO:0071706	biolink:NamedThing	tumor necrosis factor superfamily cytokine production	The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	TNFSF cytokine production|TNF superfamily production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		mah	2010-03-09T02:40:35Z						biological_process											owl:Class	
GO:0034941	biolink:NamedThing	pyrrole-2-carboxylate decarboxylase activity	Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2.	got7fsn_ti												EC:4.1.1.93|UM-BBD_reactionID:r0970		molecular_function											owl:Class	
GO:0047346	biolink:NamedThing	aldose-1-phosphate adenylyltransferase activity	Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose.	got7fsn_ti	adenosine diphosphate glucose:orthophosphate adenylyltransferase activity|ADP sugar phosphorylase activity|ADPaldose phosphorylase activity|ADP-sugar phosphorylase activity|ADP-aldose phosphorylase activity|adenosine diphosphosugar phosphorylase activity|ADP:alpha-D-aldose-1-phosphate adenylyltransferase activity|ADP:aldose-1-phosphate adenylyltransferase activity|sugar-1-phosphate adenylyltransferase activity											MetaCyc:2.7.7.36-RXN|EC:2.7.7.36		molecular_function											owl:Class	
GO:1990199	biolink:NamedThing	MsbA transporter complex	An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD).	got7fsn_ti	MsbA dimer|MsbA complex						bhm	2013-10-01T07:49:41Z						cellular_component											owl:Class	
GO:0043190	biolink:NamedThing	ATP-binding cassette (ABC) transporter complex	A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.	got7fsn_ti	ABC-type efflux porter complex|ABC-type efflux permease complex|mating pheromone exporter|ABC-type uptake permease complex										GO:0043192|GO:0043191			cellular_component											owl:Class	
GO:0021501	biolink:NamedThing	prechordal plate formation	The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.	got7fsn_ti														biological_process											owl:Class	
GO:0047106	biolink:NamedThing	4-hydroxyphenylacetaldehyde dehydrogenase activity	Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate.	got7fsn_ti	4-HPAL dehydrogenase activity|4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase activity											MetaCyc:1.2.1.53-RXN|EC:1.2.1.53|RHEA:17273		molecular_function											owl:Class	
GO:0006237	biolink:NamedThing	deoxycytidine salvage	Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0061818	biolink:NamedThing	tRNA folding	The process of assisting in the folding of tRNAs into the correct tertiary structure.	got7fsn_ti							dph	2016-12-13T15:54:40Z						biological_process											owl:Class	
GO:0034337	biolink:NamedThing	RNA folding	The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.	got7fsn_ti	RNA chaperone													biological_process											owl:Class	
GO:0001981	biolink:NamedThing	baroreceptor detection of arterial stretch	The series of events by which the change in diameter of an artery is detected and converted to a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0070259	biolink:NamedThing	tyrosyl-DNA phosphodiesterase activity	Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.	got7fsn_ti					See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'.									molecular_function											owl:Class	
GO:0098881	biolink:NamedThing	exocytic insertion of neurotransmitter receptor to plasma membrane	The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion.	got7fsn_ti	neurotransmitter receptor insertion													biological_process											owl:Class	
GO:0090522	biolink:NamedThing	vesicle tethering involved in exocytosis	The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding  to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.	got7fsn_ti	vesicle tethering to plasma membrane						tb	2013-01-08T15:07:50Z						biological_process											owl:Class	
GO:0008630	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to DNA damage	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	DNA damage response, signal transduction resulting in induction of apoptosis													biological_process											owl:Class	
GO:0001127	biolink:NamedThing	transcription open complex formation at bacterial-type RNA polymerase promoter	Any process involved in the melting of the DNA hybrid of the core promoter region within a bacterial-type RNA polymerase promoter to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.	got7fsn_ti	transcriptional open complex formation at bacterial-type RNA polymerase promoter						krc	2010-12-06T04:04:16Z						biological_process											owl:Class	
GO:0001112	biolink:NamedThing	DNA-templated transcription open complex formation	Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.	got7fsn_ti	promoter melting|DNA-dependent transcriptional open complex formation|DNA-templated transcriptional open complex formation						krc	2010-12-02T02:15:04Z						biological_process											owl:Class	
GO:0050032	biolink:NamedThing	L-rhamnonate dehydratase activity	Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O.	got7fsn_ti	L-rhamnonate hydro-lyase activity|L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming)											KEGG_REACTION:R03774|EC:4.2.1.90|MetaCyc:L-RHAMNONATE-DEHYDRATASE-RXN|RHEA:23080		molecular_function											owl:Class	
GO:0018364	biolink:NamedThing	peptidyl-glutamine methylation	The addition of a methyl group to a glutamine residue in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0043041	biolink:NamedThing	amino acid activation for nonribosomal peptide biosynthetic process	Activation of an amino acid for incorporation into a peptide by a nonribosomal process.	got7fsn_ti	nonribosomal amino acid activation													biological_process											owl:Class	
GO:0043038	biolink:NamedThing	amino acid activation	The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.	got7fsn_ti														biological_process											owl:Class	
GO:0042741	biolink:NamedThing	endogenous antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.	got7fsn_ti	endogenous antibiotic catabolism|endogenous antibiotic degradation|endogenous antibiotic breakdown													biological_process											owl:Class	
GO:0004902	biolink:NamedThing	granulocyte colony-stimulating factor receptor activity	Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	granulocyte colony stimulating factor receptor activity|G-CSF receptor activity|CSF3R										GO:0030524			molecular_function											owl:Class	
GO:0019332	biolink:NamedThing	aerobic respiration, using nitrite as electron donor	The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.	got7fsn_ti	nitrite oxidation											MetaCyc:P282-PWY		biological_process											owl:Class	
GO:0019696	biolink:NamedThing	toluene oxidation via toluene-cis-1,2-dihydrodiol	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol.	got7fsn_ti												MetaCyc:TOLUENE-DEG-DIOL-PWY		biological_process											owl:Class	
GO:0140027	biolink:NamedThing	establishment of contractile vacuole localization	The directed movement of the contractile vacuole to a specific location.	got7fsn_ti							pg	2017-05-02T10:23:26Z						biological_process											owl:Class	
GO:0051656	biolink:NamedThing	establishment of organelle localization	The directed movement of an organelle to a specific location.	got7fsn_ti	establishment of organelle localisation													biological_process											owl:Class	
GO:0140447	biolink:NamedThing	cytokine precursor processing	The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine.	got7fsn_ti	interleukin maturation|interleukin processing	https://github.com/geneontology/go-ontology/issues/19216					pg	2020-04-03T12:49:29Z						biological_process											owl:Class	
GO:0140448	biolink:NamedThing	signaling receptor ligand precursor processing	The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand.	got7fsn_ti	ligand maturation|signal maturation	https://github.com/geneontology/go-ontology/issues/19216					pg	2020-04-03T13:30:04Z			GO:0035638			biological_process											owl:Class	
GO:0010322	biolink:NamedThing	regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).	got7fsn_ti	regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway													biological_process											owl:Class	
GO:0032504	biolink:NamedThing	multicellular organism reproduction	The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.	got7fsn_ti														biological_process											owl:Class	
GO:0000003	biolink:NamedThing	reproduction	The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.	got7fsn_ti	reproductive physiological process										GO:0050876|GO:0019952	Wikipedia:Reproduction		biological_process											owl:Class	
GO:0048001	biolink:NamedThing	erythrose-4-phosphate dehydrogenase activity	Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH.	got7fsn_ti	D-erythrose 4-phosphate:NAD+ oxidoreductase activity|E4PDH|GapB|Epd dehydrogenase activity|E4P dehydrogenase activity|erythrose 4-phosphate dehydrogenase activity										GO:0033724	KEGG_REACTION:R01825|RHEA:12056|EC:1.2.1.72|MetaCyc:ERYTH4PDEHYDROG-RXN		molecular_function											owl:Class	
GO:0051661	biolink:NamedThing	maintenance of centrosome location	Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of centrosome localization													biological_process											owl:Class	
GO:0061054	biolink:NamedThing	dermatome development	The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.	got7fsn_ti							dph	2010-03-02T12:07:37Z						biological_process											owl:Class	
GO:0000808	biolink:NamedThing	origin recognition complex	A multisubunit complex that is located at the replication origins of a chromosome.	got7fsn_ti	origin of replication recognition complex|ORC											Wikipedia:Origin_recognition_complex		cellular_component											owl:Class	
GO:0043919	biolink:NamedThing	agmatine aminopropyltransferase activity	Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine.	got7fsn_ti	agmatine aminopropyl transferase activity											EC:2.5.1.104		molecular_function											owl:Class	
GO:0052723	biolink:NamedThing	inositol hexakisphosphate 1-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate.	got7fsn_ti							ai	2011-08-16T11:47:36Z				MetaCyc:RXN-10972|RHEA:37459|EC:2.7.4.21|KEGG_REACTION:R05799		molecular_function											owl:Class	
GO:0001207	biolink:NamedThing	histone displacement	The removal of histones, including histone dimers, from nucleosomes within chromatin.	got7fsn_ti							krc	2012-03-27T10:56:56Z						biological_process											owl:Class	
GO:0061510	biolink:NamedThing	asymmetric protein localization to new mitotic spindle pole body	Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically.	got7fsn_ti							dph	2013-02-21T13:49:54Z						biological_process											owl:Class	
GO:0061492	biolink:NamedThing	asymmetric protein localization to old or new spindle pole body	Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically.	got7fsn_ti							dph	2012-12-06T15:23:15Z						biological_process											owl:Class	
GO:0047790	biolink:NamedThing	creatinine deaminase activity	Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3.	got7fsn_ti	creatinine desiminase activity|creatinine hydrolase|creatinine iminohydrolase activity											MetaCyc:CREATININE-DEAMINASE-RXN|EC:3.5.4.21|RHEA:12681		molecular_function											owl:Class	
GO:0120295	biolink:NamedThing	histone serotonyltransferase activity	Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4(+).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20685					krc	2021-01-19T02:13:19Z						molecular_function											owl:Class	
GO:0120294	biolink:NamedThing	peptide serotonyltransferase activity	Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20685					krc	2021-01-19T02:07:56Z				RHEA:66552		molecular_function											owl:Class	
GO:0003294	biolink:NamedThing	atrial ventricular junction remodeling	The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle.	got7fsn_ti	atrioventricular junction remodeling|atrio-ventricular junction remodeling						dph	2009-10-22T08:35:36Z						biological_process											owl:Class	
GO:0019409	biolink:NamedThing	aerobic respiration, using ammonia as electron donor	The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite.	got7fsn_ti	aerobic ammonia oxidation to nitrite via hydrazine											MetaCyc:AMMOXID-PWY		biological_process											owl:Class	
GO:0046564	biolink:NamedThing	oxalate decarboxylase activity	Catalysis of the reaction: H(+) + oxalate = CO(2) + formate.	got7fsn_ti	oxalate carboxy-lyase (formate-forming)|oxalate carboxy-lyase activity											MetaCyc:OXALATE-DECARBOXYLASE-RXN|RHEA:16509|KEGG_REACTION:R00522|EC:4.1.1.2		molecular_function											owl:Class	
GO:0033981	biolink:NamedThing	D-dopachrome decarboxylase activity	Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2).	got7fsn_ti	phenylpyruvate tautomerase II activity|dopachrome decarboxylase activity|dopachrome conversion activity|D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming) activity|D-dopachrome carboxy-lyase activity|D-dopachrome tautomerase activity|D-tautomerase activity										GO:0030928	KEGG_REACTION:R07313|MetaCyc:4.1.1.84-RXN|EC:4.1.1.84|RHEA:18441		molecular_function											owl:Class	
GO:0050826	biolink:NamedThing	response to freezing	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.	got7fsn_ti	antifreeze activity|ice nucleation inhibitor activity													biological_process											owl:Class	
GO:0030504	biolink:NamedThing	inorganic diphosphate transmembrane transporter activity	Enables the transfer of inorganic diphosphate across a membrane.	got7fsn_ti	inorganic pyrophosphate transporter activity											Reactome:R-HSA-5226964		molecular_function											owl:Class	
GO:0015103	biolink:NamedThing	inorganic anion transmembrane transporter activity	Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.	got7fsn_ti														molecular_function											owl:Class	
GO:0030875	biolink:NamedThing	rDNA protrusion	Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining.	got7fsn_ti	ribosomal DNA protrusion				Note that this component is characterized in Schizosaccharomyces, particularly with respect to the DAPI staining pattern.									cellular_component											owl:Class	
GO:0043182	biolink:NamedThing	vacuolar sequestering of sodium ion	The process of transporting sodium ions into, and confining within, a vacuole.	got7fsn_ti	sodium ion (Na+) retention in vacuole|sequestration of sodium ion (Na+) in vacuole|vacuolar sequestering of sodium ion (Na+)|vacuolar sodium ion (Na+) retention|vacuolar sodium ion (Na+) storage|sodium ion (Na+) storage in vacuole|vacuolar sequestration of sodium ion (Na+)|sequestering of sodium ion (Na+) in vacuole													biological_process											owl:Class	
GO:0043181	biolink:NamedThing	vacuolar sequestering	The process of transporting a substance into, and confining within, a vacuole.	got7fsn_ti	vacuolar sequestration|storage in vacuole|retention in vacuole|sequestering in vacuole|vacuolar retention|sequestration in vacuole|vacuolar storage													biological_process											owl:Class	
GO:0050065	biolink:NamedThing	lysine-pyruvate 6-transaminase activity	Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine.	got7fsn_ti	Lys-AT|lysine-pyruvate aminotransferase activity|lysine--pyruvate 6-aminotransferase activity|L-lysine:pyruvate aminotransferase activity											MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN|KEGG_REACTION:R00453|MetaCyc:PWY-5324|EC:2.6.1.71|RHEA:19393		molecular_function											owl:Class	
GO:0051594	biolink:NamedThing	detection of glucose	The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	glucose perception|glucose sensing|glucose detection													biological_process											owl:Class	
GO:0009732	biolink:NamedThing	detection of hexose stimulus	The series of events in which a stimulus from a hexose is received and converted into a molecular signal.	got7fsn_ti	perception of hexose stimulus													biological_process											owl:Class	
GO:0140651	biolink:NamedThing	futile creatine cycle	The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21517					pg	2021-05-26T06:40:18Z						biological_process											owl:Class	
GO:0120316	biolink:NamedThing	sperm flagellum assembly	The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium).	got7fsn_ti							krc	2021-04-29T01:27:27Z						biological_process											owl:Class	
GO:0072360	biolink:NamedThing	vascular cord development	The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.	got7fsn_ti							mah	2010-11-16T11:46:55Z						biological_process											owl:Class	
GO:0042715	biolink:NamedThing	dosage compensation complex assembly involved in dosage compensation by hypoactivation of X chromosome	The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on both X chromosomes in the monogametic sex, ultimately resulting in a two-fold reduction in transcription from these chromosomes. An example of this process is found in Caenorhabditis elegans.	got7fsn_ti	dosage compensation complex assembly during dosage compensation by hypoactivation of X chromosome													biological_process											owl:Class	
GO:0071110	biolink:NamedThing	histone biotinylation	The modification of a histone by the addition of a biotinyl group.	got7fsn_ti							mah	2009-11-13T01:22:59Z						biological_process											owl:Class	
GO:1990888	biolink:NamedThing	2-polyprenyl-6-hydroxyphenol O-methyltransferase activity	Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+.	got7fsn_ti							sl	2015-10-28T22:31:13Z						molecular_function											owl:Class	
GO:0007406	biolink:NamedThing	negative regulation of neuroblast proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.	got7fsn_ti	inhibition of neuroblast proliferation|downregulation of neuroblast proliferation|down-regulation of neuroblast proliferation|down regulation of neuroblast proliferation|suppression of neuroblast proliferation													biological_process											owl:Class	
GO:0002342	biolink:NamedThing	central B cell deletion	The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.	got7fsn_ti	central B-lymphocyte deletion|central B lymphocyte deletion|central B-cell deletion													biological_process											owl:Class	
GO:0002516	biolink:NamedThing	B cell deletion	The apoptotic death of B cells which is part of B cell tolerance induction.	got7fsn_ti	B-lymphocyte deletion|B-cell deletion|B lymphocyte deletion													biological_process											owl:Class	
GO:0036122	biolink:NamedThing	BMP binding	Binding to a member of the bone morphogenetic protein (BMP) family.	got7fsn_ti	bone morphogenetic protein binding						bf	2012-02-20T02:59:34Z						molecular_function											owl:Class	
GO:0043732	biolink:NamedThing	6-hydroxynicotinate dehydrogenase activity	Catalysis of the reaction: 6-hydroxynicotinate + H(2)O + O(2) = 2,6-dihydroxynicotinate + H(2)O(2).	got7fsn_ti	6-hydroxynicotinate:O2 oxidoreductase activity|6-hydroxynicotinate hydroxylase activity|6-hydroxynicotinic acid hydroxylase activity|6-hydroxynicotinic acid dehydrogenase activity											MetaCyc:RXN-7585|KEGG_REACTION:R07221|EC:1.17.3.3|RHEA:22808		molecular_function											owl:Class	
GO:0016727	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.	got7fsn_ti												EC:1.17.3.-		molecular_function											owl:Class	
GO:0018275	biolink:NamedThing	N-terminal peptidyl-cysteine acetylation	The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine.	got7fsn_ti	peptidyl-cysteine N-acetylation										GO:0017191	RESID:AA0043		biological_process											owl:Class	
GO:1903531	biolink:NamedThing	negative regulation of secretion by cell	Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.	got7fsn_ti	downregulation of secretion by cell|inhibition of secretion by cell|down-regulation of cellular secretion|negative regulation of cellular secretion|inhibition of cellular secretion|down-regulation of secretion by cell|down regulation of cellular secretion|down regulation of secretion by cell|downregulation of cellular secretion						pm	2014-10-08T13:25:08Z						biological_process											owl:Class	
GO:1990273	biolink:NamedThing	snRNA 5'-end processing	Any process involved in forming the mature 5' end of an snRNA molecule.	got7fsn_ti							al	2014-01-15T15:32:06Z						biological_process											owl:Class	
GO:0016180	biolink:NamedThing	snRNA processing	Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0034044	biolink:NamedThing	exomer complex	A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues.	got7fsn_ti														cellular_component											owl:Class	
GO:0018171	biolink:NamedThing	peptidyl-cysteine oxidation	The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.	got7fsn_ti												RESID:AA0205|RESID:AA0262		biological_process											owl:Class	
GO:1904252	biolink:NamedThing	negative regulation of bile acid metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process.	got7fsn_ti	down regulation of bile acid metabolic process|negative regulation of bile acid metabolism|downregulation of bile acid metabolism|downregulation of bile acid metabolic process|inhibition of bile acid metabolic process|inhibition of bile acid metabolism|down-regulation of bile acid metabolic process|down-regulation of bile acid metabolism|down regulation of bile acid metabolism						bf	2015-05-20T11:04:35Z						biological_process											owl:Class	
GO:0031324	biolink:NamedThing	negative regulation of cellular metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.	got7fsn_ti	down regulation of cellular metabolic process|inhibition of cellular metabolic process|down-regulation of cellular metabolic process|negative regulation of cellular metabolism|downregulation of cellular metabolic process													biological_process											owl:Class	
GO:1903708	biolink:NamedThing	positive regulation of hemopoiesis	Any process that activates or increases the frequency, rate or extent of hemopoiesis.	got7fsn_ti	positive regulation of blood cell formation|activation of blood cell biosynthesis|upregulation of blood cell biosynthesis|upregulation of haemopoiesis|up regulation of hematopoiesis|up-regulation of hemopoiesis|positive regulation of haemopoiesis|positive regulation of blood cell biosynthesis|upregulation of hematopoiesis|upregulation of blood cell formation|up-regulation of blood cell biosynthesis|up regulation of haemopoiesis|upregulation of hemopoiesis|up regulation of blood cell biosynthesis|activation of hemopoiesis|up-regulation of haemopoiesis|activation of hematopoiesis|positive regulation of hematopoiesis|up regulation of hemopoiesis|up-regulation of hematopoiesis|up regulation of blood cell formation|activation of blood cell formation|activation of haemopoiesis|up-regulation of blood cell formation				An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.		pad	2014-12-04T15:34:30Z						biological_process											owl:Class	
GO:0009641	biolink:NamedThing	shade avoidance	Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome.	got7fsn_ti												Wikipedia:Shade_avoidance		biological_process											owl:Class	
GO:0055020	biolink:NamedThing	positive regulation of cardiac muscle fiber development	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.	got7fsn_ti	up regulation of cardiac muscle fiber development|activation of cardiac muscle fiber development|upregulation of cardiac muscle fiber development|positive regulation of cardiac muscle fibre development|positive regulation of heart muscle fiber development|stimulation of cardiac muscle fiber development|up-regulation of cardiac muscle fiber development													biological_process											owl:Class	
GO:0075243	biolink:NamedThing	oospore formation	The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0043935	biolink:NamedThing	sexual sporulation resulting in formation of a cellular spore	The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	got7fsn_ti														biological_process											owl:Class	
GO:0032188	biolink:NamedThing	establishment of actomyosin contractile ring localization	The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis.	got7fsn_ti	establishment of contractile ring localization involved in cytokinesis during cell cycle|cytokinesis site selection by contractile ring positioning|contractile ring positioning|actomyosin ring positioning|establishment of contractile ring localization involved in cell cycle cytokinesis|establishment of contractile ring localisation involved in cell cycle cytokinesis													biological_process											owl:Class	
GO:0032187	biolink:NamedThing	actomyosin contractile ring localization	The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle.	got7fsn_ti	contractile ring localisation involved in cell cycle cytokinesis|contractile ring localization involved in cell cycle cytokinesis													biological_process											owl:Class	
GO:0032482	biolink:NamedThing	Rab protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.	got7fsn_ti														biological_process											owl:Class	
GO:0007265	biolink:NamedThing	Ras protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.	got7fsn_ti	Ras mediated signal transduction													biological_process											owl:Class	
GO:0102605	biolink:NamedThing	cyclooctat-9-en-5,7-diol C18-monooxygenase activity	Catalysis of the reaction: cyclooctat-9-en-5,7-diol + O2 + NADPH + H+ <=> cyclooctatin + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-15430|RHEA:56824		molecular_function											owl:Class	
GO:0103030	biolink:NamedThing	ethylglyoxal reductase (NADH-dependent, hydroxyacetone-forming) activity	Catalysis of the reaction: H+ + methylglyoxal + NADH = hydroxyacetone + NAD.	got7fsn_ti												RHEA:35615|MetaCyc:RXN0-5213		molecular_function											owl:Class	
GO:0008093	biolink:NamedThing	cytoskeletal anchor activity	The binding activity of a protein that brings together a cytoskeletal protein (either a microtubule or actin filament, spindle pole body, or protein directly bound to them) and one or more other molecules, permitting them to function in a coordinated way.	got7fsn_ti	cytoskeletal adaptor activity	https://github.com/geneontology/go-ontology/issues/19119|https://github.com/geneontology/go-ontology/issues/17668												molecular_function											owl:Class	
GO:0072295	biolink:NamedThing	specification of metanephric distal tubule identity	The process in which the distal tubule of the metanephric nephron acquires its identity.	got7fsn_ti							mah	2010-04-09T04:01:42Z						biological_process											owl:Class	
GO:0072084	biolink:NamedThing	specification of distal tubule identity	The process in which the distal tubule of the kidney nephron acquires its identity.	got7fsn_ti							mah	2010-02-01T02:47:53Z						biological_process											owl:Class	
GO:0042265	biolink:NamedThing	peptidyl-asparagine hydroxylation	The hydroxylation of peptidyl-asparagine to form peptidyl-hydroxyasparagine.	got7fsn_ti	peptidyl-aspartic acid/asparagine hydroxylation													biological_process											owl:Class	
GO:0071166	biolink:NamedThing	ribonucleoprotein complex localization	Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.	got7fsn_ti	RNP localization|ribonucleoprotein complex localisation|cellular ribonucleoprotein complex localization|establishment and maintenance of ribonucleoprotein complex localization						mah	2009-11-19T04:46:05Z						biological_process											owl:Class	
GO:0004111	biolink:NamedThing	creatine kinase activity	Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+).	got7fsn_ti	MB-CK|MiMi-CK|MM-CK|BB-CK|CK-MB|creatine phosphokinase activity|CK-MM|adenosine triphosphate-creatine transphosphorylase activity|ATP:creatine N-phosphotransferase activity|ATP:creatine phosphotransferase activity|CK-BB|creatine phosphotransferase activity|CKMiMi|Mi-CK|phosphocreatine kinase activity|CK											Reactome:R-HSA-200326|EC:2.7.3.2|Reactome:R-HSA-200318|RHEA:17157|MetaCyc:CREATINE-KINASE-RXN|KEGG_REACTION:R01881		molecular_function											owl:Class	
GO:0047530	biolink:NamedThing	2,4-diaminopentanoate dehydrogenase activity	Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+.	got7fsn_ti	2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating)|2,4-diaminopentanoic acid C4 dehydrogenase activity											EC:1.4.1.12|MetaCyc:24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0060585	biolink:NamedThing	positive regulation of prostaglandin-endoperoxide synthase activity	Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.	got7fsn_ti	positive regulation of (PG)H synthase activity|positive regulation of fatty acid cyclooxygenase activity|positive regulation of PG synthetase activity|positive regulation of prostaglandin synthetase activity						dph	2009-05-08T02:12:34Z						biological_process											owl:Class	
GO:0051353	biolink:NamedThing	positive regulation of oxidoreductase activity	Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.	got7fsn_ti	stimulation of oxidoreductase activity|ribonucleotide reductase activating enzyme activity|activation of oxidoreductase activity|up-regulation of oxidoreductase activity|up regulation of oxidoreductase activity|upregulation of oxidoreductase activity|oxidoreductase activator										GO:0009391			biological_process											owl:Class	
GO:0044159	biolink:NamedThing	host thylakoid	A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.	got7fsn_ti							jl	2009-08-11T04:15:34Z						cellular_component											owl:Class	
GO:1990825	biolink:NamedThing	sequence-specific mRNA binding	Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.	got7fsn_ti							sl	2015-08-19T17:42:50Z						molecular_function											owl:Class	
GO:0047841	biolink:NamedThing	dehydrogluconokinase activity	Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H(+).	got7fsn_ti	2-ketogluconate kinase activity|dehydogluconokinase activity|ketogluconokinase activity|ATP:2-dehydro-D-gluconate 6-phosphotransferase activity|2-ketogluconokinase activity|ketogluconokinase (phosphorylating)											RHEA:10788|KEGG_REACTION:R02658|EC:2.7.1.13|MetaCyc:DEHYDOGLUCONOKINASE-RXN		molecular_function											owl:Class	
GO:0004445	biolink:NamedThing	inositol-polyphosphate 5-phosphatase activity	Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.	got7fsn_ti	Ins(1,4,5)P(3) 5-phosphatase activity|inositol-1,4,5-trisphosphate 5-phosphatase activity|D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity|D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity|inositol 1,4,5-trisphosphate phosphatase activity|inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase activity|5PTase activity|Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity|InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase activity|type II inositol polyphosphate 5-phosphatase activity|InsP3/Ins(1,3,4,5)P4 5-phosphatase activity|inositol trisphosphate phosphomonoesterase activity|type II inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol phosphate 5-phosphomonoesterase activity|inositol polyphosphate-5-phosphatase activity|L-myo-inositol 1,4,5-trisphosphate-monoesterase activity|type I inositol-polyphosphate phosphatase activity|1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity|D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity|Ins(1,4,5)P3 5-phosphatase activity|myo-inositol-1,4,5-trisphosphate 5-phosphatase activity|inosine triphosphatase activity|inositol triphosphate 5-phosphomonoesterase activity				Note that this is a compound function and should be replaced by 'GO:0052659 : inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity' and 'GO:0052658 : inositol-1,4,5-trisphosphate 5-phosphatase activity'.							EC:3.1.3.56		molecular_function											owl:Class	
GO:0006338	biolink:NamedThing	chromatin remodeling	Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.	got7fsn_ti	ATP-dependent chromatin remodelling|ATP-dependent chromatin remodeling|chromatin modelling|chromatin modeling|chromatin remodelling	https://github.com/geneontology/go-ontology/issues/21732									GO:0043044			biological_process											owl:Class	
GO:0006561	biolink:NamedThing	proline biosynthetic process	The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.	got7fsn_ti	proline formation|proline biosynthesis|proline anabolism|proline synthesis											MetaCyc:PWY-3341|MetaCyc:PROSYN-PWY		biological_process											owl:Class	
GO:0000325	biolink:NamedThing	plant-type vacuole	A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.	got7fsn_ti	vacuole, cell cycle-independent morphology													cellular_component											owl:Class	
GO:0033651	biolink:NamedThing	host cell plastid	Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														cellular_component											owl:Class	
GO:0070820	biolink:NamedThing	tertiary granule	A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.	got7fsn_ti	gelatinase granule						mah	2009-07-20T03:57:00Z						cellular_component											owl:Class	
GO:0035578	biolink:NamedThing	azurophil granule lumen	The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.	got7fsn_ti	primary granule lumen						bf	2010-10-05T01:30:33Z						cellular_component											owl:Class	
GO:0034774	biolink:NamedThing	secretory granule lumen	The volume enclosed by the membrane of a secretory granule.	got7fsn_ti														cellular_component											owl:Class	
GO:0140507	biolink:NamedThing	granzyme-mediated programmed cell death signaling pathway	A series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cell death in target cells.	got7fsn_ti	granzyme-mediated cell death signaling pathway	https://github.com/geneontology/go-ontology/issues/19901|http://wiki.geneontology.org/index.php/Apoptosis_Curation_Manual#Other_children_of_apoptotic_signaling_pathway					pg	2020-08-27T13:51:40Z						biological_process											owl:Class	
GO:0034691	biolink:NamedThing	integrin alphaE-beta7 complex	An integrin complex that comprises one alphaE subunit and one beta7 subunit.	got7fsn_ti	Itgae-Itgb7 complex													cellular_component											owl:Class	
GO:0045806	biolink:NamedThing	negative regulation of endocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.	got7fsn_ti	downregulation of endocytosis|inhibition of endocytosis|down regulation of endocytosis|down-regulation of endocytosis													biological_process											owl:Class	
GO:0055059	biolink:NamedThing	asymmetric neuroblast division	The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.	got7fsn_ti														biological_process											owl:Class	
GO:0045499	biolink:NamedThing	chemorepellent activity	Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.	got7fsn_ti	chemorepellant activity													molecular_function											owl:Class	
GO:0019922	biolink:NamedThing	protein-chromophore linkage via peptidyl-cysteine	The covalent linking of a chromophore to a protein via peptidyl-cysteines.	got7fsn_ti														biological_process											owl:Class	
GO:0034294	biolink:NamedThing	sexual spore wall assembly	The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.	got7fsn_ti	sexual spore wall formation													biological_process											owl:Class	
GO:0042244	biolink:NamedThing	spore wall assembly	The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore.	got7fsn_ti	spore coat biosynthetic process|spore wall formation|spore coat biosynthesis													biological_process											owl:Class	
GO:0102306	biolink:NamedThing	benzil reductase [(S)-benzoin-forming] activity	Catalysis of the reaction: (S)-benzoin + NADP(3-) <=> benzil + NADPH(4-) + H+.	got7fsn_ti												EC:1.1.1.320|MetaCyc:RXN-12898|RHEA:25968		molecular_function											owl:Class	
GO:0048207	biolink:NamedThing	vesicle targeting, rough ER to cis-Golgi	The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi.	got7fsn_ti	vesicle targeting, rough endoplasmic reticulum to cis-Golgi|rough ER to cis-Golgi targeting|rough endoplasmic reticulum to cis-Golgi targeting													biological_process											owl:Class	
GO:0048199	biolink:NamedThing	vesicle targeting, to, from or within Golgi	The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.	got7fsn_ti	vesicle targeting, to, from or within dictyosome|Golgi vesicle targeting|dictyosome vesicle targeting													biological_process											owl:Class	
GO:0032347	biolink:NamedThing	regulation of aldosterone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.	got7fsn_ti														biological_process											owl:Class	
GO:0033973	biolink:NamedThing	dCTP deaminase (dUMP-forming) activity	Catalysis of the reaction: dCTP + 2 H(2)O = diphosphate + dUMP + H(+) + NH(4)(+).	got7fsn_ti	dCTP aminohydrolase (dUMP-forming) activity											EC:3.5.4.30|RHEA:19205|MetaCyc:3.5.4.30-RXN|KEGG_REACTION:R07307		molecular_function											owl:Class	
GO:0033675	biolink:NamedThing	pericanalicular vesicle	A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes.	got7fsn_ti														cellular_component											owl:Class	
GO:0071165	biolink:NamedThing	GINS complex assembly	The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks.	got7fsn_ti							mah	2009-11-19T03:37:20Z						biological_process											owl:Class	
GO:0071428	biolink:NamedThing	rRNA-containing ribonucleoprotein complex export from nucleus	The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm.	got7fsn_ti	rRNA-containing ribonucleoprotein complex export from cell nucleus|rRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|rRNA-containing RNP export from nucleus|rRNA-containing ribonucleoprotein complex nucleus export						mah	2009-12-16T10:15:07Z						biological_process											owl:Class	
GO:0019902	biolink:NamedThing	phosphatase binding	Binding to a phosphatase.	got7fsn_ti														molecular_function											owl:Class	
GO:0010174	biolink:NamedThing	nucleoside transmembrane transporter activity, against a concentration gradient	Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient.	got7fsn_ti	concentrative nucleoside transporter activity													molecular_function											owl:Class	
GO:0015089	biolink:NamedThing	high-affinity copper ion transmembrane transporter activity	Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity copper transporter activity|high affinity copper ion transmembrane transporter activity													molecular_function											owl:Class	
GO:0018484	biolink:NamedThing	4-hydroxybenzaldehyde dehydrogenase activity	Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+.	got7fsn_ti	p-hydroxybenzaldehyde dehydrogenase activity|3-hydroxybenzaldehyde:NAD+ oxidoreductase activity											UM-BBD_reactionID:r0273|MetaCyc:HYDROXYBENZALDEHYDE-OXIDATION-NAD-RXN|RHEA:20305|EC:1.2.1.64		molecular_function											owl:Class	
GO:0050244	biolink:NamedThing	pyruvate oxidase (CoA-acetylating) activity	Catalysis of the reaction: CoA + H(+) + O(2) + pyruvate = acetyl-CoA + CO(2) + H(2)O(2).	got7fsn_ti	pyruvate:oxygen 2-oxidoreductase (CoA-acetylating)											EC:1.2.3.6|MetaCyc:PYRUVATE-OXIDASE-COA-ACETYLATING-RXN|RHEA:21912|KEGG_REACTION:R00211		molecular_function											owl:Class	
GO:0042697	biolink:NamedThing	menopause	Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Menopause		biological_process											owl:Class	
GO:0034881	biolink:NamedThing	citrazinate hydrolase activity	Catalysis of the reaction: citrazinate + H2O = cis-aconitamide.	got7fsn_ti												UM-BBD_reactionID:r1343		molecular_function											owl:Class	
GO:0070788	biolink:NamedThing	conidiophore stalk development	The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.	got7fsn_ti							mah	2009-07-08T01:31:44Z						biological_process											owl:Class	
GO:0140655	biolink:NamedThing	mitochondrial proliferation	The multiplication of mitochondria, resulting in the expansion of the number of mitochondria within a cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21537					pg	2021-06-04T10:23:02Z						biological_process											owl:Class	
GO:0002758	biolink:NamedThing	innate immune response-activating signal transduction	A series of molecular signals generated as a consequence of a pathogen or microbial effector binding to a plant 'resistance-gene' receptor to activate a plant immune response, usually plant-type hypersensitive response.	got7fsn_ti	defense response signaling pathway, resistance gene-independent|effector-triggered immune signaling|effector-triggered immunity|defense response signalling pathway, resistance gene-dependent|defense response signaling pathway, resistance gene-dependent|defence response signalling pathway, resistance gene-dependent|defence response signaling pathway, resistance gene-independent|effector triggered immunity|defence response signalling pathway, resistance gene-independent|defence response signaling pathway, resistance gene-dependent	https://github.com/geneontology/go-ontology/issues/18733|https://github.com/geneontology/go-ontology/issues/18587|https://github.com/geneontology/go-ontology/issues/19850|https://github.com/geneontology/go-ontology/issues/18586									GO:0010204|GO:0009870			biological_process											owl:Class	
GO:0002218	biolink:NamedThing	activation of innate immune response	Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.	got7fsn_ti											GO:0002219			biological_process											owl:Class	
GO:0102588	biolink:NamedThing	cyanidin 3-O-glucoside 6''-O-malonyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A.	got7fsn_ti												MetaCyc:RXN-15335|EC:2.3.1.171		molecular_function											owl:Class	
GO:0048451	biolink:NamedThing	petal formation	The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti											GO:0048419			biological_process											owl:Class	
GO:0019928	biolink:NamedThing	peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid	The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid.	got7fsn_ti												RESID:AA0314		biological_process											owl:Class	
GO:0003119	biolink:NamedThing	regulation of vasoconstriction by neuronal epinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings.	got7fsn_ti	regulation of vasoconstriction by neuronal adrenaline													biological_process											owl:Class	
GO:0003115	biolink:NamedThing	regulation of vasoconstriction by epinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings.	got7fsn_ti														biological_process											owl:Class	
GO:0000823	biolink:NamedThing	inositol-1,4,5-trisphosphate 6-kinase activity	Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H(+).	got7fsn_ti	inositol polyphosphate multikinase activity|inositol trisphosphate 6-kinase activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity|IpmK											MetaCyc:2.7.1.151-RXN|EC:2.7.1.151|KEGG_REACTION:R05800		molecular_function											owl:Class	
GO:0051766	biolink:NamedThing	inositol trisphosphate kinase activity	Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP.	got7fsn_ti														molecular_function											owl:Class	
GO:0006849	biolink:NamedThing	plasma membrane pyruvate transport	The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:1901475	biolink:NamedThing	pyruvate transmembrane transport	The directed movement of pyruvate across a membrane.	got7fsn_ti	pyruvate membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2012-10-04T20:52:54Z						biological_process											owl:Class	
GO:0018042	biolink:NamedThing	C-terminal peptidyl-histidine amidation	The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0089		biological_process											owl:Class	
GO:0035739	biolink:NamedThing	CD4-positive, alpha-beta T cell proliferation	The expansion of a CD4-positive, alpha-beta T cell population by cell division.	got7fsn_ti							bf	2011-03-17T02:12:48Z						biological_process											owl:Class	
GO:0046633	biolink:NamedThing	alpha-beta T cell proliferation	The expansion of an alpha-beta T cell population by cell division.	got7fsn_ti	alpha-beta T-cell proliferation|alpha-beta T-lymphocyte proliferation|alpha-beta T lymphocyte proliferation													biological_process											owl:Class	
GO:0089717	biolink:NamedThing	spanning component of membrane	The component of a membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0016021	biolink:NamedThing	integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to membrane|transmembrane											Wikipedia:Transmembrane_protein		cellular_component											owl:Class	
GO:0098979	biolink:NamedThing	polyadic synapse	A synapse consisting of a single presynapse and multiple postsynapses.  These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems.	got7fsn_ti														cellular_component											owl:Class	
GO:0045202	biolink:NamedThing	synapse	The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.	got7fsn_ti	electrotonic synapse|mixed synapse|synaptic junction											NIF_Subcellular:sao914572699|Wikipedia:Chemical_synapse		cellular_component											owl:Class	
GO:0060262	biolink:NamedThing	negative regulation of N-terminal protein palmitoylation	Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0050748	biolink:NamedThing	negative regulation of lipoprotein metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	got7fsn_ti	negative regulation of lipoprotein metabolism|down regulation of lipoprotein metabolic process|downregulation of lipoprotein metabolic process|down-regulation of lipoprotein metabolic process|inhibition of lipoprotein metabolic process													biological_process											owl:Class	
GO:0010397	biolink:NamedThing	apiogalacturonan metabolic process	The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.	got7fsn_ti	apiogalacturonan metabolism													biological_process											owl:Class	
GO:0009521	biolink:NamedThing	photosystem	A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species.	got7fsn_ti	reaction center|reaction centre										GO:0030090	Wikipedia:Photosystem		cellular_component											owl:Class	
GO:0050407	biolink:NamedThing	[glycogen-synthase-D] phosphatase activity	Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate.	got7fsn_ti	uridine diphosphoglucose-glycogen glucosyltransferase phosphatase activity|UDP-glycogen glucosyltransferase phosphatase activity|UDP-glucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity|glycogen synthase D phosphatase activity|UDPglucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity|glycogen synthase phosphatase activity|glycogen synthetase phosphatase activity|glycogen-synthase-D phosphatase activity|phosphatase type 2oC|Mg2+ dependent glycogen synthase phosphatase activity|glycogen glucosyltransferase phosphatase activity|UDPglucose-glycogen glucosyltransferase phosphatase activity											EC:3.1.3.42|MetaCyc:GLYCOGEN-SYNTHASE-D-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0019065	biolink:NamedThing	receptor-mediated endocytosis of virus by host cell	Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell.	got7fsn_ti	receptor mediated endocytosis by host of virus particle|viral entry into host cell via receptor-mediated endocytosis|receptor mediated endocytosis of virus particle by host|virus receptor-mediated endocytosis by host|receptor-mediated endocytosis of virus by host|receptor mediated endocytosis of virus by host|viral receptor mediated endocytosis													biological_process											owl:Class	
GO:0006898	biolink:NamedThing	receptor-mediated endocytosis	An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.	got7fsn_ti	receptor mediated endocytosis											Wikipedia:Receptor-mediated_endocytosis		biological_process											owl:Class	
GO:0031241	biolink:NamedThing	periplasmic side of cell outer membrane	The side (leaflet) of the outer membrane that faces the periplasm of the cell.	got7fsn_ti	internal side of cell outer membrane|internal leaflet of cell outer membrane|internal side of outer membrane				In GO, 'internal side' still refers to part of the membrane and does not refer to components beyond (inside of) the membrane.									cellular_component											owl:Class	
GO:0098552	biolink:NamedThing	side of membrane	A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface.	got7fsn_ti							dos	2013-12-03T11:28:04Z						cellular_component											owl:Class	
GO:0048479	biolink:NamedThing	style development	The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.	got7fsn_ti														biological_process											owl:Class	
GO:0035146	biolink:NamedThing	tube fusion	The joining of specific branches of a tubular system to form a continuous network.	got7fsn_ti														biological_process											owl:Class	
GO:0048674	biolink:NamedThing	collateral sprouting of injured axon	The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons.	got7fsn_ti														biological_process											owl:Class	
GO:0048668	biolink:NamedThing	collateral sprouting	The process in which outgrowths develop from the shafts of existing axons.	got7fsn_ti	axon branching													biological_process											owl:Class	
GO:0090325	biolink:NamedThing	regulation of locomotion involved in locomotory behavior	Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.	got7fsn_ti							tb	2010-05-14T10:24:29Z						biological_process											owl:Class	
GO:0016204	biolink:NamedThing	determination of muscle attachment site	The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site.	got7fsn_ti														biological_process											owl:Class	
GO:0071990	biolink:NamedThing	maintenance of protein location to spindle pole body	Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere.	got7fsn_ti	maintenance of protein location at spindle pole body|maintenance of protein location in spindle pole body						mah	2010-10-25T11:02:31Z						biological_process											owl:Class	
GO:0072595	biolink:NamedThing	maintenance of protein localization in organelle	Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.	got7fsn_ti	maintenance of protein localization to organelle|maintenance of protein localisation to organelle						mah	2011-02-14T02:09:13Z						biological_process											owl:Class	
GO:0004334	biolink:NamedThing	fumarylacetoacetase activity	Catalysis of the reaction: 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate + H(+).	got7fsn_ti	4-fumarylacetoacetate fumarylhydrolase activity|beta-diketonase activity|fumarylacetoacetate hydrolase activity											UM-BBD_reactionID:r0107|Reactome:R-HSA-71181|EC:3.7.1.2|KEGG_REACTION:R01364|MetaCyc:FUMARYLACETOACETASE-RXN|RHEA:10244		molecular_function											owl:Class	
GO:0071048	biolink:NamedThing	nuclear retention of unspliced pre-mRNA at the site of transcription	The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription.	got7fsn_ti							krc	2009-08-11T02:19:03Z						biological_process											owl:Class	
GO:0071033	biolink:NamedThing	nuclear retention of pre-mRNA at the site of transcription	The process involved in retention of aberrant or improperly formed mRNAs, e.g. those that are incorrectly or incompletely spliced or that have incorrectly formed 3'-ends, within the nucleus at the site of transcription.	got7fsn_ti							krc	2009-07-28T04:35:54Z						biological_process											owl:Class	
GO:0004924	biolink:NamedThing	oncostatin-M receptor activity	Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0043953	biolink:NamedThing	protein transport by the Tat complex	The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex.	got7fsn_ti	twin-arginine translocation pathway|protein secretion by the TAT complex|protein translocation by the twin-arginine translocation complex|protein translocation by the TAT complex				Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'TAT protein translocation system complex ; GO:0033281'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported.									biological_process											owl:Class	
GO:0060063	biolink:NamedThing	Spemann organizer formation at the embryonic shield	Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan.	got7fsn_ti	Spemann-Mangold organizer formation at the embryonic shield|Spemann's organizer formation at the embryonic shield				Occurs in Teleost fish.									biological_process											owl:Class	
GO:0060061	biolink:NamedThing	Spemann organizer formation	Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.	got7fsn_ti	Spemann's organizer formation|Spemann-Mangold organizer formation													biological_process											owl:Class	
GO:0016008	biolink:NamedThing	major mitochondrial derivative	The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20737												cellular_component											owl:Class	
GO:0042243	biolink:NamedThing	asexual spore wall assembly	The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species.	got7fsn_ti	asexual spore wall formation													biological_process											owl:Class	
GO:0010213	biolink:NamedThing	non-photoreactive DNA repair	A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated.	got7fsn_ti	light-independent DNA repair													biological_process											owl:Class	
GO:0006281	biolink:NamedThing	DNA repair	The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.	got7fsn_ti												Wikipedia:DNA_repair		biological_process											owl:Class	
GO:0042539	biolink:NamedThing	hypotonic salinity response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti	response to hypotonic salt stress													biological_process											owl:Class	
GO:0006971	biolink:NamedThing	hypotonic response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.	got7fsn_ti	hypo-osmotic response													biological_process											owl:Class	
GO:0007463	biolink:NamedThing	R2/R5 cell fate commitment	The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres.	got7fsn_ti														biological_process											owl:Class	
GO:0102901	biolink:NamedThing	isopimaradienol hydroxylase activity	Catalysis of the reaction: H+ + isopimaradienol + NADPH + O2 <=> isopimaradiene-diol + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-8536		molecular_function											owl:Class	
GO:0050834	biolink:NamedThing	molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide	The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.	got7fsn_ti												RESID:AA0355		biological_process											owl:Class	
GO:0009271	biolink:NamedThing	phage shock	A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage.	got7fsn_ti														biological_process											owl:Class	
GO:0010456	biolink:NamedThing	cell proliferation in dorsal spinal cord	The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0061578	biolink:NamedThing	Lys63-specific deubiquitinase activity	Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein.	got7fsn_ti							dph	2013-11-15T19:13:12Z				Reactome:R-HSA-5691411|Reactome:R-HSA-741411|Reactome:R-HSA-8869506|Reactome:R-HSA-936390|Reactome:R-HSA-5690856|Reactome:R-HSA-5696547|Reactome:R-HSA-936381|Reactome:R-HSA-5357845|Reactome:R-HSA-5691439|Reactome:R-HSA-5691431|Reactome:R-HSA-688136		molecular_function											owl:Class	
GO:0101005	biolink:NamedThing	deubiquitinase activity	Catalysis of the hydrolysis of ubiquitin from proteins.	got7fsn_ti	ubiquitinyl hydrolase activity|deubiquitinase activity	https://github.com/geneontology/go-ontology/issues/17398			There are two main classes of deubiquitinating enzymes: cysteine proteases (i.e., thiol dependent) and metalloproteases.		mec	2016-02-08T09:39:38Z			GO:1904265	Reactome:R-HSA-9674127		molecular_function											owl:Class	
GO:0051563	biolink:NamedThing	smooth endoplasmic reticulum calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.	got7fsn_ti	smooth ER calcium ion concentration regulation|calcium ion homeostasis in smooth endoplasmic reticulum|regulation of calcium ion concentration in smooth ER|regulation of smooth ER calcium ion concentration|regulation of smooth endoplasmic reticulum calcium ion concentration|smooth endoplasmic reticulum calcium ion concentration regulation|regulation of calcium ion concentration in smooth endoplasmic reticulum|calcium ion homeostasis in smooth ER|smooth ER calcium ion homeostasis													biological_process											owl:Class	
GO:0032469	biolink:NamedThing	endoplasmic reticulum calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.	got7fsn_ti	ER calcium ion concentration regulation|endoplasmic reticulum calcium ion concentration regulation|regulation of ER calcium ion concentration|regulation of calcium ion concentration in ER|regulation of endoplasmic reticulum calcium ion concentration|ER calcium ion homeostasis|regulation of calcium ion concentration in endoplasmic reticulum|calcium ion homeostasis in endoplasmic reticulum|calcium ion homeostasis in ER													biological_process											owl:Class	
GO:0070757	biolink:NamedThing	interleukin-35-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-35 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-35-mediated signalling pathway|IL-35-mediated signaling pathway						mah	2009-06-23T01:55:02Z						biological_process											owl:Class	
GO:0102096	biolink:NamedThing	decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity	Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+.	got7fsn_ti												RHEA:34487|MetaCyc:RXN-11070|EC:2.4.1.289		molecular_function											owl:Class	
GO:1901440	biolink:NamedThing	poly(hydroxyalkanoate) metabolic process	The chemical reactions and pathways involving poly(hydroxyalkanoate).	got7fsn_ti	poly(hydroxyalkanoate) metabolism						tt	2012-10-02T01:47:26Z						biological_process											owl:Class	
GO:0017159	biolink:NamedThing	pantetheine hydrolase activity	Catalysis of the reaction: (R)-pantetheine + H(2)O = (R)-pantothenate + cysteamine.	got7fsn_ti	vanin|(R)-pantetheine amidohydrolase activity|vanin-1|pantetheinase activity											Reactome:R-HSA-8938300|EC:3.5.1.92|RHEA:13445|MetaCyc:3.5.1.92-RXN|KEGG_REACTION:R02973		molecular_function											owl:Class	
GO:0071279	biolink:NamedThing	cellular response to cobalt ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.	got7fsn_ti							mah	2009-12-10T03:55:55Z						biological_process											owl:Class	
GO:0032025	biolink:NamedThing	response to cobalt ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0102458	biolink:NamedThing	cyanidin 3-O-glucoside 5-O glucosyltransferase (vanilloyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> cyanin betaine + vanillate + H+.	got7fsn_ti												MetaCyc:RXN-13970|EC:2.4.1.299		molecular_function											owl:Class	
GO:0034725	biolink:NamedThing	DNA replication-dependent nucleosome disassembly	The controlled breakdown of nucleosomes on newly replicated DNA, coupled to strand elongation.	got7fsn_ti														biological_process											owl:Class	
GO:0008659	biolink:NamedThing	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O.	got7fsn_ti	(3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase activity|(3R)-hydroxymyristoyl-ACP dehydratase activity											EC:4.2.1.59|RHEA:41892		molecular_function											owl:Class	
GO:0042441	biolink:NamedThing	eye pigment metabolic process	The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.	got7fsn_ti	eye pigment metabolism													biological_process											owl:Class	
GO:0043324	biolink:NamedThing	pigment metabolic process involved in developmental pigmentation	The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism.	got7fsn_ti	pigment metabolism during developmental pigmentation|pigment metabolic process during developmental pigmentation													biological_process											owl:Class	
GO:0004575	biolink:NamedThing	sucrose alpha-glucosidase activity	Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose.	got7fsn_ti	sucrose hydrolysis|beta-D-fructofuranosyl alpha-D-glucopyranoside hydrolysis|sucrase activity|sucrose alpha-glucohydrolase activity|alpha-D-glucopyranosyl beta-D-fructofuranoside hydrolysis|sucrase(invertase)|sucrose-alpha-D-glucohydrolase activity|intestinal sucrase activity|sucrose alpha-D-glucohydrolase activity|sucrase-isomaltase activity											Reactome:R-HSA-5659926|Reactome:R-HSA-189069|RHEA:33795|MetaCyc:RXN-1461|KEGG_REACTION:R00802|EC:3.2.1.48		molecular_function											owl:Class	
GO:0004564	biolink:NamedThing	beta-fructofuranosidase activity	Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.	got7fsn_ti	beta-D-fructofuranoside fructohydrolase activity|invertase activity|beta-h-fructosidase activity|invertin activity|fructosylinvertase activity|maxinvert L 1000 activity|acid invertase activity|glucosucrase activity|saccharase activity|beta-fructosidase activity|alkaline invertase activity											MetaCyc:RXN-9985|EC:3.2.1.26		molecular_function											owl:Class	
GO:0008256	biolink:NamedThing	protein histidine pros-kinase activity	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.	got7fsn_ti	ATP:protein-L-histidine N-pros-phosphotransferase activity|ATP:protein-L-histidine Npi-phosphotransferase activity|protein-histidine pros-kinase activity|HK2											RHEA:22720|EC:2.7.13.1|MetaCyc:2.7.13.1-RXN		molecular_function											owl:Class	
GO:0004673	biolink:NamedThing	protein histidine kinase activity	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.	got7fsn_ti	HK1|EnvZ|histidine protein kinase activity|histidine kinase activity|protein kinase (histidine) (ambiguous)|Sln1p|ATP:protein-L-histidine N-phosphotransferase activity|histidine kinase (ambiguous)|protein-histidine kinase activity|HP165|histidine protein kinase (ambiguous)|protein histidine kinase (ambiguous)|protein kinase (histidine)										GO:0008896	MetaCyc:2.7.13.3-RXN|EC:2.7.13.3		molecular_function											owl:Class	
GO:0090596	biolink:NamedThing	sensory organ morphogenesis	Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti							tb	2014-08-22T13:23:20Z						biological_process											owl:Class	
GO:0016581	biolink:NamedThing	NuRD complex	An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.	got7fsn_ti	NRD complex|nucleosome remodeling and histone deacetylation complex|Mi-2 complex													cellular_component											owl:Class	
GO:0005667	biolink:NamedThing	transcription regulator complex	A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.	got7fsn_ti	nuclear transcription factor complex|cytoplasmic transcription factor complex|transcription factor complex						jl	2013-08-28T12:11:37Z			GO:0044798|GO:0044797			cellular_component											owl:Class	
GO:0033854	biolink:NamedThing	glutamate-prephenate aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate.	got7fsn_ti	L-arogenate:2-oxoglutarate aminotransferase activity|PAT|prephenate transaminase activity|L-glutamate:prephenate aminotransferase activity											MetaCyc:PREPHENATE-TRANSAMINE-RXN|RHEA:22880|KEGG_REACTION:R07276|EC:2.6.1.79		molecular_function											owl:Class	
GO:0019263	biolink:NamedThing	adamantanone catabolic process	The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.	got7fsn_ti	adamantanone catabolism|adamantanone breakdown|adamantanone degradation											MetaCyc:P481-PWY		biological_process											owl:Class	
GO:0098508	biolink:NamedThing	endothelial to hematopoietic transition	The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium.	got7fsn_ti							dos	2013-09-24T15:20:39Z						biological_process											owl:Class	
GO:0099643	biolink:NamedThing	signal release from synapse	Any signal release from a synapse.	got7fsn_ti														biological_process											owl:Class	
GO:0018547	biolink:NamedThing	nitroglycerin reductase activity	Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative.	got7fsn_ti	NG reductase activity											UM-BBD_enzymeID:e0038		molecular_function											owl:Class	
GO:0016663	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen.	got7fsn_ti												EC:1.7.3.-		molecular_function											owl:Class	
GO:0007344	biolink:NamedThing	pronuclear fusion	The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome.	got7fsn_ti														biological_process											owl:Class	
GO:0000741	biolink:NamedThing	karyogamy	The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.	got7fsn_ti	nuclear fusion during karyogamy|nuclear fusion										GO:0007335	Wikipedia:Karyogamy		biological_process											owl:Class	
GO:0009991	biolink:NamedThing	response to extracellular stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0034674	biolink:NamedThing	integrin alpha5-beta1 complex	An integrin complex that comprises one alpha5 subunit and one beta1 subunit.	got7fsn_ti	VLA-5 complex|alpha5-beta1 integrin complex|ITGA5-ITGB1 complex													cellular_component											owl:Class	
GO:0039008	biolink:NamedThing	pronephric nephron tubule morphogenesis	The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.	got7fsn_ti							bf	2010-07-02T09:45:55Z						biological_process											owl:Class	
GO:0099576	biolink:NamedThing	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0042176	biolink:NamedThing	regulation of protein catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	got7fsn_ti	regulation of protein degradation|regulation of protein catabolism|regulation of protein breakdown													biological_process											owl:Class	
GO:0071674	biolink:NamedThing	mononuclear cell migration	The movement of a mononuclear cell within or between different tissues and organs of the body.	got7fsn_ti							mah	2010-02-16T02:11:00Z						biological_process											owl:Class	
GO:0034265	biolink:NamedThing	isopentenyl adenine biosynthetic process	The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.	got7fsn_ti	isopentenyl adenine anabolism|isopentenyl adenine biosynthesis|isopentenyl adenine formation|isopentenyladenine biosynthetic process|isopentenyl adenine synthesis													biological_process											owl:Class	
GO:0009691	biolink:NamedThing	cytokinin biosynthetic process	The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.	got7fsn_ti	cytokinin synthesis|cytokinin formation|cytokinin biosynthesis|cytokinin anabolism													biological_process											owl:Class	
GO:0000271	biolink:NamedThing	polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	got7fsn_ti	polysaccharide synthesis|polysaccharide formation|polysaccharide anabolism|glycan biosynthesis|polysaccharide biosynthesis|glycan biosynthetic process													biological_process											owl:Class	
GO:0005976	biolink:NamedThing	polysaccharide metabolic process	The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	got7fsn_ti	polysaccharide metabolism|glycan metabolism|multicellular organismal polysaccharide metabolic process|glycan metabolic process										GO:0044263			biological_process											owl:Class	
GO:0001196	biolink:NamedThing	regulation of mating-type specific transcription from RNA polymerase II promoter	Any mating-type specific process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti							krc	2011-11-23T09:25:32Z						biological_process											owl:Class	
GO:0019708	biolink:NamedThing	peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine	The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins.	got7fsn_ti	peptidyl-glycine cholesteryl ester anabolism from peptidyl-glycine|peptidyl-glycine cholesteryl ester synthesis from peptidyl-glycine|peptidyl-glycine cholesteryl ester formation from peptidyl-glycine											RESID:AA0309		biological_process											owl:Class	
GO:0008203	biolink:NamedThing	cholesterol metabolic process	The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.	got7fsn_ti	cholesterol metabolism													biological_process											owl:Class	
GO:0002483	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.	got7fsn_ti	endogenous peptide antigen processing and presentation													biological_process											owl:Class	
GO:0048002	biolink:NamedThing	antigen processing and presentation of peptide antigen	The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.	got7fsn_ti	peptide antigen processing and presentation|antigen presentation, peptide antigen													biological_process											owl:Class	
GO:0050801	biolink:NamedThing	ion homeostasis	Any process involved in the maintenance of an internal steady state of ions within an organism or cell.	got7fsn_ti	negative regulation of crystal formation|electrolyte homeostasis|regulation of ion homeostasis										GO:2000021			biological_process											owl:Class	
GO:0051073	biolink:NamedThing	adenosylcobinamide-GDP ribazoletransferase activity	Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.	got7fsn_ti	adenosylcobinamide-GDP:alpha-ribazole ribazoletransferase activity|cobalamin-5'-phosphate synthase activity|cobalamin (5'-phosphate) synthase activity|cobalamin synthase activity|CobS											MetaCyc:COBALAMINSYN-RXN|EC:2.7.8.26|RHEA:16049		molecular_function											owl:Class	
GO:0072069	biolink:NamedThing	DCT cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state.	got7fsn_ti	distal convoluted tubule cell differentiation						mah	2010-01-25T04:17:22Z						biological_process											owl:Class	
GO:0061005	biolink:NamedThing	cell differentiation involved in kidney development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.	got7fsn_ti							dph	2010-01-21T09:13:55Z						biological_process											owl:Class	
GO:0051310	biolink:NamedThing	metaphase plate congression	The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle.	got7fsn_ti	chromosome congression													biological_process											owl:Class	
GO:0032885	biolink:NamedThing	regulation of polysaccharide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.	got7fsn_ti														biological_process											owl:Class	
GO:0050182	biolink:NamedThing	phosphate butyryltransferase activity	Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA.	got7fsn_ti	butanoyl-CoA:phosphate butanoyltransferase activity|phosphotransbutyrylase activity											KEGG_REACTION:R01174|MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN|EC:2.3.1.19|RHEA:20892		molecular_function											owl:Class	
GO:0033708	biolink:NamedThing	isocitrate-homoisocitrate dehydrogenase activity	Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+.	got7fsn_ti	isocitrate(homoisocitrate):NAD+ oxidoreductase (decarboxylating) activity|homoisocitrate-isocitrate dehydrogenase activity|PH1722											EC:1.1.1.286|MetaCyc:RXN-7969		molecular_function											owl:Class	
GO:0047769	biolink:NamedThing	arogenate dehydratase activity	Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2.	got7fsn_ti	L-arogenate hydro-lyase (decarboxylating)|L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming)|carboxycyclohexadienyl dehydratase activity											MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN|EC:4.2.1.91|RHEA:12536		molecular_function											owl:Class	
GO:0033879	biolink:NamedThing	acetylajmaline esterase activity	Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate.	got7fsn_ti	2beta(R)-17-O-acetylajmalan:acetylesterase activity|AAE|acetylajmalan esterase activity|17-O-acetylajmaline O-acetylhydrolase activity											MetaCyc:RXN-8652|MetaCyc:RXN-8653|EC:3.1.1.80		molecular_function											owl:Class	
GO:1900581	biolink:NamedThing	(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process	The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol.	got7fsn_ti	(17Z)-protosta-17(20),24-dien-3beta-ol formation|(17Z)-protosta-17(20),24-dien-3beta-ol synthesis|(17Z)-protosta-17(20),24-dien-3beta-ol anabolism|(17Z)-protosta-17(20),24-dien-3beta-ol biosynthesis						di	2012-05-15T06:47:38Z						biological_process											owl:Class	
GO:1990133	biolink:NamedThing	molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	A heterodimeric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin (MPT) cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; Moco biosynthesis and its constituent molecules are evolutionarily conserved.	got7fsn_ti							bhm	2013-06-26T10:54:21Z						cellular_component											owl:Class	
GO:0042247	biolink:NamedThing	establishment of planar polarity of follicular epithelium	Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates.	got7fsn_ti														biological_process											owl:Class	
GO:0080029	biolink:NamedThing	cellular response to boron-containing substance levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances.	got7fsn_ti	cellular response to boron levels													biological_process											owl:Class	
GO:0070887	biolink:NamedThing	cellular response to chemical stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-08-27T04:41:45Z						biological_process											owl:Class	
GO:1905169	biolink:NamedThing	regulation of protein localization to phagocytic vesicle	Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle.	got7fsn_ti	regulation of protein localization in phagocytic vesicle|regulation of protein localisation to phagocytic vesicle|regulation of protein recruitment to phagosome|regulation of protein localisation to phagosome|regulation of protein localisation in phagocytic vesicle						bf	2016-05-02T18:38:13Z						biological_process											owl:Class	
GO:0031863	biolink:NamedThing	prostaglandin D2 receptor binding	Binding to a prostaglandin D2 receptor.	got7fsn_ti	prostaglandin D2 receptor ligand|prostanoid DP receptor binding													molecular_function											owl:Class	
GO:1990130	biolink:NamedThing	GATOR1 complex	A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins.	got7fsn_ti	SEACIT complex|IML1 complex	https://github.com/geneontology/go-ontology/issues/21778			The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ;  GO:1990131.		rb	2013-06-25T17:34:40Z						cellular_component											owl:Class	
GO:0106237	biolink:NamedThing	arachidonate 12(R)-lipoxygenase activity	Catalysis of the reaction: arachidonate + O(2)=(5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.	got7fsn_ti							hjd	2019-12-18T21:03:02Z				RHEA:41336		molecular_function											owl:Class	
GO:0042832	biolink:NamedThing	defense response to protozoan	Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.	got7fsn_ti	defense response to protozoan, incompatible interaction|defence response to protozoon|defence response to protozoa|resistance response to pathogenic protozoa|defense response to protozoon|defense response to protozoa|defense response to pathogenic protozoa|resistance response to pathogenic protozoan|defence response to pathogenic protozoa										GO:0009818			biological_process											owl:Class	
GO:0001562	biolink:NamedThing	response to protozoan	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.	got7fsn_ti	response to protozoon|response to protozoa|resistance to pathogenic protozoa										GO:0042833			biological_process											owl:Class	
GO:0090717	biolink:NamedThing	adaptive immune memory response involving T cells and B cells	An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.	got7fsn_ti							tb	2016-11-11T12:35:19Z						biological_process											owl:Class	
GO:0002460	biolink:NamedThing	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.	got7fsn_ti														biological_process											owl:Class	
GO:0001326	biolink:NamedThing	replication of extrachromosomal circular DNA	Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.	got7fsn_ti														biological_process											owl:Class	
GO:2000385	biolink:NamedThing	positive regulation of ectoderm development	Any process that activates or increases the frequency, rate or extent of ectoderm development.	got7fsn_ti							vk	2011-02-15T03:17:39Z						biological_process											owl:Class	
GO:0002942	biolink:NamedThing	tRNA m2,2-guanine biosynthesis	The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.	got7fsn_ti							hjd	2012-11-16T16:07:20Z						biological_process											owl:Class	
GO:0048094	biolink:NamedThing	male pigmentation	Establishment of a pattern of pigment in males.	got7fsn_ti														biological_process											owl:Class	
GO:0003331	biolink:NamedThing	positive regulation of extracellular matrix constituent secretion	Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.	got7fsn_ti							dph	2009-11-02T02:11:22Z						biological_process											owl:Class	
GO:1903532	biolink:NamedThing	positive regulation of secretion by cell	Any process that activates or increases the frequency, rate or extent of secretion by cell.	got7fsn_ti	upregulation of secretion by cell|upregulation of cellular secretion|activation of cellular secretion|up regulation of secretion by cell|up regulation of cellular secretion|positive regulation of cellular secretion|up-regulation of cellular secretion|activation of secretion by cell|up-regulation of secretion by cell						pm	2014-10-08T13:25:17Z						biological_process											owl:Class	
GO:0018282	biolink:NamedThing	metal incorporation into metallo-sulfur cluster	The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide.	got7fsn_ti	metal incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0002110	biolink:NamedThing	cotranscriptional mitochondrial rRNA nucleotide insertion	The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.	got7fsn_ti														biological_process											owl:Class	
GO:0030327	biolink:NamedThing	prenylated protein catabolic process	The chemical reactions and pathways resulting in the breakdown of prenylated proteins.	got7fsn_ti	prenylated protein breakdown|prenylated protein degradation|prenylated protein catabolism													biological_process											owl:Class	
GO:0019941	biolink:NamedThing	modification-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.	got7fsn_ti	modification-dependent protein breakdown|protein degradation tagging activity|modification-dependent proteolysis|protein-ligand-dependent protein catabolic process|protein-ligand-dependent protein catabolism|modification-initiated proteolysis|modification-dependent protein catabolism|modification-initiated protein catabolism|modification-initiated protein catabolic process|modification-dependent protein degradation													biological_process											owl:Class	
GO:0036161	biolink:NamedThing	calcitonin secretion	The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.	got7fsn_ti							bf	2012-03-26T01:30:32Z						biological_process											owl:Class	
GO:0016029	biolink:NamedThing	subrhabdomeral cisterna	A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase.	got7fsn_ti	submicrovillar cisterna|SMC													cellular_component											owl:Class	
GO:0120082	biolink:NamedThing	smooth endoplasmic reticulum cisterna	A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.	got7fsn_ti							krc	2017-07-05T23:32:11Z						cellular_component											owl:Class	
GO:0045792	biolink:NamedThing	negative regulation of cell size	Any process that reduces cell size.	got7fsn_ti	down-regulation of cell size|down regulation of cell size|inhibition of cell size|downregulation of cell size													biological_process											owl:Class	
GO:0008361	biolink:NamedThing	regulation of cell size	Any process that modulates the size of a cell.	got7fsn_ti	cell size control													biological_process											owl:Class	
GO:0035323	biolink:NamedThing	male germline ring canal	An intercellular bridge that connects the germline cells of a male cyst.	got7fsn_ti	spermatocyte ring canal|testicular ring canal						bf	2010-02-25T11:05:14Z						cellular_component											owl:Class	
GO:0045172	biolink:NamedThing	germline ring canal	Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.	got7fsn_ti														cellular_component											owl:Class	
GO:0106330	biolink:NamedThing	sialate 9-O-acetylesterase activity	Catalysis of the reaction: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate.	got7fsn_ti							hjd	2020-09-30T19:38:44Z				RHEA:22600|EC:3.1.1.53		molecular_function											owl:Class	
GO:0034609	biolink:NamedThing	spicule insertion	Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.	got7fsn_ti														biological_process											owl:Class	
GO:0014825	biolink:NamedThing	stomach fundus smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.	got7fsn_ti														biological_process											owl:Class	
GO:0014847	biolink:NamedThing	proximal stomach smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.	got7fsn_ti														biological_process											owl:Class	
GO:0034439	biolink:NamedThing	lipoprotein lipid oxidation	The modification of a lipoprotein by oxidation of the lipid group.	got7fsn_ti														biological_process											owl:Class	
GO:0034440	biolink:NamedThing	lipid oxidation	The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.	got7fsn_ti														biological_process											owl:Class	
GO:0045940	biolink:NamedThing	positive regulation of steroid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.	got7fsn_ti	up regulation of steroid metabolic process|stimulation of steroid metabolic process|upregulation of steroid metabolic process|positive regulation of steroid metabolism|up-regulation of steroid metabolic process|activation of steroid metabolic process													biological_process											owl:Class	
GO:0045834	biolink:NamedThing	positive regulation of lipid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.	got7fsn_ti	activation of lipid metabolic process|upregulation of lipid metabolic process|up-regulation of lipid metabolic process|stimulation of lipid metabolic process|positive regulation of lipid metabolism|up regulation of lipid metabolic process													biological_process											owl:Class	
GO:0035909	biolink:NamedThing	aorta morphogenesis	The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.	got7fsn_ti							bf	2011-06-24T11:11:11Z						biological_process											owl:Class	
GO:0070915	biolink:NamedThing	lysophosphatidic acid receptor activity	Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.	got7fsn_ti	LPA receptor activity						mah	2009-09-10T05:05:13Z						molecular_function											owl:Class	
GO:0045125	biolink:NamedThing	bioactive lipid receptor activity	Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.	got7fsn_ti														molecular_function											owl:Class	
GO:0005927	biolink:NamedThing	muscle tendon junction	A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.	got7fsn_ti	myotendinous junction													cellular_component											owl:Class	
GO:0030055	biolink:NamedThing	cell-substrate junction	A cell junction that forms a connection between a cell and the extracellular matrix.	got7fsn_ti	cell-matrix junction													cellular_component											owl:Class	
GO:0022835	biolink:NamedThing	transmitter-gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	neurotransmitter-gated channel activity|extracellular substance gated channel activity													molecular_function											owl:Class	
GO:0022834	biolink:NamedThing	ligand-gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0005977	biolink:NamedThing	glycogen metabolic process	The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.	got7fsn_ti	glycogen metabolism													biological_process											owl:Class	
GO:0006112	biolink:NamedThing	energy reserve metabolic process	The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.	got7fsn_ti	energy reserve metabolism													biological_process											owl:Class	
GO:0035869	biolink:NamedThing	ciliary transition zone	A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.	got7fsn_ti	connecting cilium|cilial transition zone|cilium transition zone				Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.		bf	2011-05-25T03:09:58Z						cellular_component											owl:Class	
GO:0047011	biolink:NamedThing	2-dehydropantolactone reductase (A-specific) activity	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.	got7fsn_ti	2-dehydropantoyl-lactone reductase (A-specific) activity|ketopantoyl lactone reductase activity|(R)-pantolactone:NADP+ oxidoreductase (A-specific)|2-ketopantoyl lactone reductase activity|2-oxopantoyl lactone reductase											MetaCyc:1.1.1.168-RXN|EC:1.1.1.168		molecular_function											owl:Class	
GO:0010629	biolink:NamedThing	negative regulation of gene expression	Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	got7fsn_ti					This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation.									biological_process											owl:Class	
GO:0072242	biolink:NamedThing	metanephric DCT cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.	got7fsn_ti	metanephric distal convoluted tubule cell fate commitment						mah	2010-03-19T03:27:00Z						biological_process											owl:Class	
GO:0072146	biolink:NamedThing	DCT cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell.	got7fsn_ti	distal convoluted tubule cell fate commitment						mah	2010-02-24T01:59:04Z						biological_process											owl:Class	
GO:0060138	biolink:NamedThing	fetal process involved in parturition	A reproductive process occurring in the embryo that results in birth.	got7fsn_ti														biological_process											owl:Class	
GO:0020008	biolink:NamedThing	rhoptry	A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole.	got7fsn_ti	paired organelles|toxoneme											Wikipedia:Rhoptry		cellular_component											owl:Class	
GO:0032808	biolink:NamedThing	lacrimal gland development	The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.	got7fsn_ti														biological_process											owl:Class	
GO:0030076	biolink:NamedThing	light-harvesting complex	A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center.	got7fsn_ti	antenna complex											Wikipedia:Light-harvesting_complex		cellular_component											owl:Class	
GO:0016554	biolink:NamedThing	cytidine to uridine editing	The conversion of a cytosine residue to uridine in an RNA molecule by deamination.	got7fsn_ti														biological_process											owl:Class	
GO:0016553	biolink:NamedThing	base conversion or substitution editing	Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).	got7fsn_ti	base conversion/substitution editing													biological_process											owl:Class	
GO:0050745	biolink:NamedThing	peptide cross-linking via L-cysteinyl-5-imidazolinone glycine	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.	got7fsn_ti												RESID:AA0188		biological_process											owl:Class	
GO:0043915	biolink:NamedThing	L-seryl-tRNA(Sec) kinase activity	Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).	got7fsn_ti	O-phosphoseryl-tRNA(Sec) kinase activity											MetaCyc:RXN-10038|EC:2.7.1.164|RHEA:25037		molecular_function											owl:Class	
GO:0018480	biolink:NamedThing	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity	Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+.	got7fsn_ti	5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity|carboxymethylhydroxymuconic semialdehyde dehydrogenase activity											EC:1.2.1.60|RHEA:15681|UM-BBD_reactionID:r0365|MetaCyc:CHMS-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0060230	biolink:NamedThing	lipoprotein lipase activator activity	Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.	got7fsn_ti														molecular_function											owl:Class	
GO:0045581	biolink:NamedThing	negative regulation of T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.	got7fsn_ti	negative regulation of T-lymphocyte differentiation|down regulation of T cell differentiation|inhibition of T cell differentiation|negative regulation of T cell development|negative regulation of T-cell differentiation|negative regulation of T lymphocyte differentiation|downregulation of T cell differentiation|down-regulation of T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0045580	biolink:NamedThing	regulation of T cell differentiation	Any process that modulates the frequency, rate or extent of T cell differentiation.	got7fsn_ti	regulation of T-cell differentiation|regulation of T lymphocyte differentiation|regulation of T-lymphocyte differentiation|regulation of T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0030850	biolink:NamedThing	prostate gland development	The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.	got7fsn_ti	prostate development													biological_process											owl:Class	
GO:0015313	biolink:NamedThing	fluconazole:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out).	got7fsn_ti	fluconazole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0045119	biolink:NamedThing	azole:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances.	got7fsn_ti	bicyclomycin/sulfathiazole:hydrogen antiporter activity|azole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0021825	biolink:NamedThing	substrate-dependent cerebral cortex tangential migration	The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions.	got7fsn_ti														biological_process											owl:Class	
GO:0021800	biolink:NamedThing	cerebral cortex tangential migration	The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.	got7fsn_ti														biological_process											owl:Class	
GO:0021742	biolink:NamedThing	abducens nucleus development	The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0097218	biolink:NamedThing	sieve plate	A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas.	got7fsn_ti					Typical of angiosperms. Part of sieve tube member (PO:0000289).		pr	2012-01-13T05:42:48Z						cellular_component											owl:Class	
GO:1902556	biolink:NamedThing	phosphatidylinositol transporter complex	A protein complex which is capable of phosphatidylinositol transporter activity.	got7fsn_ti	Ire1 complex dimer|Ire1 complex homooligomer|Ire1 complex homodimer				An example is PDR16 in S. cerevisiae (UniProt ID P53860) in PMID:9890948 (inferred from direct assay).		bhm	2013-12-06T16:12:25Z						cellular_component											owl:Class	
GO:1990351	biolink:NamedThing	transporter complex	A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.	got7fsn_ti					An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).		bhm	2014-03-26T14:23:27Z						cellular_component											owl:Class	
GO:0044833	biolink:NamedThing	modulation by virus of host protein transport	Any viral process that modulates the frequency, rate or extent of protein transport in its host organism.	got7fsn_ti							jl	2014-02-06T13:25:52Z						biological_process											owl:Class	
GO:0032036	biolink:NamedThing	myosin heavy chain binding	Binding to a heavy chain of a myosin complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0033938	biolink:NamedThing	1,6-alpha-L-fucosidase activity	Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.	got7fsn_ti	1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase activity											EC:3.2.1.127|MetaCyc:3.2.1.127-RXN		molecular_function											owl:Class	
GO:0004560	biolink:NamedThing	alpha-L-fucosidase activity	Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose.	got7fsn_ti	alpha-fucosidase activity|alpha-L-fucoside fucohydrolase activity											RHEA:12288|MetaCyc:ALPHA-L-FUCOSIDASE-RXN|Reactome:R-HSA-5693807|EC:3.2.1.51		molecular_function											owl:Class	
GO:0048464	biolink:NamedThing	flower calyx development	The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0048438	biolink:NamedThing	floral whorl development	The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant.	got7fsn_ti	collective phyllome structure development				Consider instead annotating to one of the more specific child terms, or to 'floral organ development ; GO:0048438' or one of its child terms.						GO:0048413			biological_process											owl:Class	
GO:0090713	biolink:NamedThing	immunological memory process	Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory.	got7fsn_ti							tb	2016-11-11T12:20:30Z						biological_process											owl:Class	
GO:0004315	biolink:NamedThing	3-oxoacyl-[acyl-carrier-protein] synthase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].	got7fsn_ti	beta-ketoacyl-acyl carrier protein synthase activity|beta-ketoacyl-acyl-carrier-protein synthase I|beta-ketoacyl synthetase activity|beta-ketoacylsynthase activity|beta-ketoacyl-ACP synthetase activity|acyl-malonyl acyl carrier protein-condensing enzyme activity|beta-ketoacyl-ACP synthase I activity|beta-ketoacyl-acyl-carrier-protein synthase II activity|fatty acid condensing enzyme activity|ketoacyl-ACP synthase activity|beta-ketoacyl-ACP synthase II activity|3-oxoacyl-acyl-carrier-protein synthase activity|KAS I activity|acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)|KASI|acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity|3-ketoacyl-acyl carrier protein synthase activity|beta-ketoacyl acyl carrier protein synthase activity|beta-ketoacyl-[acyl carrier protein] synthase activity|condensing enzyme activity|KAS II|KASII|3-oxoacyl-ACP synthase activity|3-oxoacyl-acyl carrier protein synthase I activity|beta-ketoacyl-acyl carrier protein synthetase activity|3-oxoacyl-[acyl-carrier protein] synthase activity|3-oxoacyl:ACP synthase I	https://github.com/geneontology/go-ontology/issues/21801									GO:0033817	MetaCyc:2.3.1.179-RXN|EC:2.3.1.179|EC:2.3.1.41|MetaCyc:3-OXOACYL-ACP-SYNTH-RXN|RHEA:22836		molecular_function											owl:Class	
GO:0000349	biolink:NamedThing	generation of catalytic spliceosome for first transesterification step	Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.	got7fsn_ti	spliceosomal C1 complex biosynthesis|formation of catalytic spliceosome for first transesterification step|catalytic spliceosome assembly for first transesterification step|spliceosomal A2-2 complex formation|spliceosomal C1 complex formation|U12-type catalytic spliceosome formation for first transesterification step|U2-type catalytic spliceosome formation for first transesterification step|spliceosomal A2-2 complex biosynthesis				Note that this step represents the formation of the A2-2 complex (yeast) or the C1 complex (mammalian).						GO:0000357|GO:0000356			biological_process											owl:Class	
GO:0022618	biolink:NamedThing	ribonucleoprotein complex assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.	got7fsn_ti	RNA-protein complex assembly|protein-RNA complex assembly|RNP complex assembly													biological_process											owl:Class	
GO:0006508	biolink:NamedThing	proteolysis	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.	got7fsn_ti	peptidolysis|ATP-dependent proteolysis				This term was intentionally placed under 'protein metabolic process ; GO:0019538' rather than 'protein catabolic process ; GO:0030163' to cover all processes centered on breaking peptide bonds, including those involved in protein processing.							Wikipedia:Proteolysis		biological_process											owl:Class	
GO:0031030	biolink:NamedThing	negative regulation of septation initiation signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.	got7fsn_ti	negative regulation of septation initiation signalling|negative regulation of septation initiation network|negative regulation of septation initiation signaling cascade|downregulation of septation initiation signaling|down regulation of septation initiation signaling|down-regulation of septation initiation signaling|inhibition of septation initiation signaling													biological_process											owl:Class	
GO:0010974	biolink:NamedThing	negative regulation of division septum assembly	Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	got7fsn_ti	negative regulation of division septum formation|inhibition of division septum assembly involved in cell cycle cytokinesis						tb	2009-06-01T10:32:32Z			GO:1901139|GO:1902469			biological_process											owl:Class	
GO:0047077	biolink:NamedThing	Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity	Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.	got7fsn_ti	Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)|Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing)|Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing)|luciferase (firefly luciferin)|firefly luciferase activity|luciferase activity|firefly luciferin luciferase activity|Photinus pyralis luciferase activity											EC:1.13.12.7|RHEA:10732|MetaCyc:1.13.12.7-RXN		molecular_function											owl:Class	
GO:0034804	biolink:NamedThing	benzo(a)pyrene 11,12-epoxidase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide.	got7fsn_ti												UM-BBD_reactionID:r1119		molecular_function											owl:Class	
GO:0032883	biolink:NamedThing	regulation of chitin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.	got7fsn_ti	regulation of chitin formation|regulation of chitin biosynthesis|regulation of chitin synthesis|regulation of chitin anabolism													biological_process											owl:Class	
GO:0017199	biolink:NamedThing	N-terminal peptidyl-threonine acetylation	The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase.	got7fsn_ti					See also the molecular function term 'peptide alpha-N-acetyltransferase activity ; GO:0004596'.							RESID:AA0052		biological_process											owl:Class	
GO:0120257	biolink:NamedThing	peptidyl-threonine acetylation	The acetylation of peptidyl-threonine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19957					krc	2020-09-08T18:01:01Z						biological_process											owl:Class	
GO:0097027	biolink:NamedThing	ubiquitin-protein transferase activator activity	Binds to and increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.	got7fsn_ti							pr	2011-03-31T05:19:23Z						molecular_function											owl:Class	
GO:0055106	biolink:NamedThing	ubiquitin-protein transferase regulator activity	Binds to and modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0036244	biolink:NamedThing	cellular response to neutral pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti							bf	2012-05-28T10:21:03Z						biological_process											owl:Class	
GO:0071467	biolink:NamedThing	cellular response to pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti							mah	2009-12-18T11:41:54Z						biological_process											owl:Class	
GO:0050177	biolink:NamedThing	phenylpyruvate decarboxylase activity	Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.	got7fsn_ti	phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming)|phenylpyruvate carboxy-lyase activity											RHEA:14185|EC:4.1.1.43|MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0102366	biolink:NamedThing	7-beta-hydroxytaxusin 2-alpha-hydroxylase activity	Catalysis of the reaction: 7-beta-hydroxytaxusin + NADPH + O2 + H+ = 2alpha, 7-beta-dihydroxytaxusin + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-13487		molecular_function											owl:Class	
GO:0051754	biolink:NamedThing	meiotic sister chromatid cohesion, centromeric	The cell cycle process in which centromeres of sister chromatids are joined during meiosis.	got7fsn_ti	sister chromatid cohesion at centromere at meiosis I|meiotic sister chromatid cohesion at centromere|centromeric meiotic sister chromatin cohesion													biological_process											owl:Class	
GO:0070601	biolink:NamedThing	centromeric sister chromatid cohesion	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.	got7fsn_ti	sister chromatid cohesion at centromere						mah	2009-04-28T04:31:00Z						biological_process											owl:Class	
GO:0043565	biolink:NamedThing	sequence-specific DNA binding	Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	got7fsn_ti	sequence specific DNA binding													molecular_function											owl:Class	
GO:0003677	biolink:NamedThing	DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	got7fsn_ti	microtubule/chromatin interaction|plasmid binding|structure specific DNA binding|structure-specific DNA binding										GO:0043566			molecular_function											owl:Class	
GO:0044481	biolink:NamedThing	envenomation resulting in proteolysis in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant hydrolysis of proteins in of the bitten organism.	got7fsn_ti							jl	2012-01-19T03:01:16Z						biological_process											owl:Class	
GO:0102432	biolink:NamedThing	quercetin 7-O-methyltransferase activity	Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine  <=> rhamnetin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13906		molecular_function											owl:Class	
GO:0044717	biolink:NamedThing	8-hydroxy-dADP phosphatase activity	Catalysis of the reaction: 8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate.	got7fsn_ti							jl	2012-10-18T13:33:32Z				Reactome:R-HSA-2395965		molecular_function											owl:Class	
GO:0017110	biolink:NamedThing	nucleoside-diphosphatase activity	Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate  + phosphate.	got7fsn_ti	NDPase activity|inosine diphosphatase|nucleoside-diphosphate phosphohydrolase activity|nucleoside diphosphatase activity|inosine 5'-diphosphatase|nucleoside diphosphate phosphohydrolase activity|apyrase activity|nucleoside diphosphate phosphatase activity|nucleoside 5'-diphosphatase activity|type L nucleoside diphosphatase|type B nucleoside diphosphatase											Reactome:R-HSA-8851129|Reactome:R-HSA-8851550|Reactome:R-HSA-8851356|MetaCyc:NUCLEOSIDE-DIPHOSPHATASE-RXN|Reactome:R-HSA-2395876|EC:3.6.1.6|Reactome:R-HSA-8850854|RHEA:36799|Reactome:R-HSA-8851225|Reactome:R-HSA-8851396		molecular_function											owl:Class	
GO:0031508	biolink:NamedThing	pericentric heterochromatin assembly	The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA.	got7fsn_ti	centromeric silencing|centromeric heterochromatin formation|chromatin silencing at pericentric region|heterochromatic silencing at centromere|centromeric heterochromatin biosynthesis|chromatin silencing at centromere|centric heterochromatin formation|centromere chromatin silencing|chromatin silencing at centromere outer repeat region	https://github.com/geneontology/go-ontology/issues/18954|https://github.com/geneontology/go-ontology/issues/19112					mah	2013-07-17T15:21:38Z			GO:1990141|GO:0030702			biological_process											owl:Class	
GO:0047206	biolink:NamedThing	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA.	got7fsn_ti	L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine 6-N-alanyltransferase activity|UDP-N-acetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity|alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide transferase activity|uridine diphosphoacetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity|UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase activity|uridine diphosphoacetylmuramoylpentapeptide lysine N6-alanyltransferase activity|L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase activity											MetaCyc:2.3.2.10-RXN|RHEA:12432|EC:2.3.2.10		molecular_function											owl:Class	
GO:0016755	biolink:NamedThing	aminoacyltransferase activity	Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring amino-acyl groups|aminoacyltransferase activity											EC:2.3.2.-		molecular_function											owl:Class	
GO:0051427	biolink:NamedThing	hormone receptor binding	Binding to a receptor for a hormone.	got7fsn_ti														molecular_function											owl:Class	
GO:0102376	biolink:NamedThing	lupeol 28-oxidase activity	Catalysis of the reaction: lupeol + 3 NADPH + 3 O2 + 3 H+ <=> betulinic acid + 3 NADP + 4 H2O.	got7fsn_ti												MetaCyc:RXN-13507		molecular_function											owl:Class	
GO:0042824	biolink:NamedThing	MHC class I peptide loading complex	A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.	got7fsn_ti	PLC|peptide-loading complex				Note that although this complex is located in the endoplasmic reticulum, there is some evidence that it may also be found in the Golgi.									cellular_component											owl:Class	
GO:0004349	biolink:NamedThing	glutamate 5-kinase activity	Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+).	got7fsn_ti	ATP-L-glutamate 5-phosphotransferase activity|ATP:L-glutamate 5-phosphotransferase activity|gamma-glutamate kinase activity|glutamate kinase activity|gamma-glutamyl kinase activity|ATP:gamma-L-glutamate phosphotransferase activity											KEGG_REACTION:R00239|RHEA:14877|MetaCyc:GLUTKIN-RXN|EC:2.7.2.11		molecular_function											owl:Class	
GO:0009728	biolink:NamedThing	detection of gibberellic acid stimulus	The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of gibberellic acid stimulus													biological_process											owl:Class	
GO:0005047	biolink:NamedThing	signal recognition particle binding	Binding to a signal recognition particle.	got7fsn_ti	signal recognition particle receptor|docking protein				See also the cellular component term 'signal recognition particle, endoplasmic reticulum targeting ; GO:0005786'.									molecular_function											owl:Class	
GO:0043021	biolink:NamedThing	ribonucleoprotein complex binding	Binding to a complex of RNA and protein.	got7fsn_ti	ribonucleoprotein binding|RNP binding|protein-RNA complex binding													molecular_function											owl:Class	
GO:0007617	biolink:NamedThing	mating behavior	The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.	got7fsn_ti	mating behaviour											Wikipedia:Mating_behaviour		biological_process											owl:Class	
GO:0019098	biolink:NamedThing	reproductive behavior	The specific behavior of an organism that is associated with reproduction.	got7fsn_ti	multi-organism reproductive behavior|reproductive behaviour|reproductive behavior in a multicellular organism|single-organism reproductive behavior|multicellular organism reproductive behavior						jl	2012-09-19T16:01:37Z			GO:0044704|GO:0033057|GO:0044705			biological_process											owl:Class	
GO:0000495	biolink:NamedThing	box H/ACA RNA 3'-end processing	Any process involved in forming the mature 3' end of a box H/ACA RNA molecule.	got7fsn_ti	box H/ACA RNA 3' end processing|box H/ACA snoRNA 3'-end processing|box H/ACA sRNA 3'-end processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0034964	biolink:NamedThing	box H/ACA RNA processing	Any process involved in the conversion of a primary box H/ACA type small  RNA transcript into a mature box H/ACA RNA.	got7fsn_ti	box H/ACA sRNA processing|box H/ACA snoRNA processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:2000995	biolink:NamedThing	negative regulation of mannan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process.	got7fsn_ti	negative regulation of mannan breakdown|negative regulation of mannan catabolism|negative regulation of mannan degradation						tt	2011-08-08T03:19:11Z						biological_process											owl:Class	
GO:2000925	biolink:NamedThing	negative regulation of cellodextrin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process.	got7fsn_ti	negative regulation of cellodextrin metabolism						tt	2011-08-01T12:39:56Z						biological_process											owl:Class	
GO:0009029	biolink:NamedThing	tetraacyldisaccharide 4'-kinase activity	Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a).	got7fsn_ti	lipid-A 4'-kinase activity|ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4'-O-phosphotransferase activity											RHEA:20700|KEGG_REACTION:R04657|MetaCyc:TETRAACYLDISACC4KIN-RXN|EC:2.7.1.130		molecular_function											owl:Class	
GO:0072479	biolink:NamedThing	response to mitotic cell cycle spindle assembly checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.	got7fsn_ti	response to Dma1-dependent checkpoint signalling|mitotic cell cycle spindle assembly checkpoint effector process|response to Dma1-dependent checkpoint signaling|response to signal involved in mitotic cell cycle spindle assembly checkpoint						mah	2010-12-09T12:11:31Z			GO:0044811			biological_process											owl:Class	
GO:0072485	biolink:NamedThing	response to spindle assembly checkpoint signaling	A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling.	got7fsn_ti	spindle assembly checkpoint effector process|response to signal involved in spindle assembly checkpoint						mah	2010-12-09T12:19:35Z						biological_process											owl:Class	
GO:1905773	biolink:NamedThing	8-hydroxy-2'-deoxyguanosine DNA binding	Binding to 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA.	got7fsn_ti							nc	2016-12-21T15:57:27Z						molecular_function											owl:Class	
GO:0106275	biolink:NamedThing	NADP+-protein-arginine ADP-ribosyltransferase activity	Catalysis of the reaction: NADP+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine.	got7fsn_ti							hjd	2020-07-02T01:39:04Z				RHEA:54884|EC:2.4.2.31		molecular_function											owl:Class	
GO:0003956	biolink:NamedThing	NAD(P)+-protein-arginine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine.	got7fsn_ti	NAD(P)+-arginine ADP-ribosyltransferase activity|NAD(P)-arginine ADP-ribosyltransferase activity|mono(ADP-ribosyl)transferase activity|mono(ADPribosyl)transferase activity|NAD+:L-arginine ADP-D-ribosyltransferase activity|NAD(P)+:L-arginine ADP-D-ribosyltransferase activity|protein-arginine ADP-ribosyltransferase activity|NAD(P)+:protein-L-arginine ADP-D-ribosyltransferase activity|NAD(P)(+)--arginine ADP-ribosyltransferase activity|ADP-ribosyltransferase activity|peptidyl-arginine ADP-ribosylation activity|NAD(+):L-arginine ADP-D-ribosyltransferase activity											MetaCyc:2.4.2.31-RXN|Reactome:R-HSA-1972385|EC:2.4.2.31		molecular_function											owl:Class	
GO:0046526	biolink:NamedThing	D-xylulose reductase activity	Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH.	got7fsn_ti	xylitol dehydrogenase activity											RHEA:20433|KEGG_REACTION:R01896|EC:1.1.1.9|MetaCyc:D-XYLULOSE-REDUCTASE-RXN|Reactome:R-HSA-5662471		molecular_function											owl:Class	
GO:0021818	biolink:NamedThing	modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration	The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.	got7fsn_ti	modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0047705	biolink:NamedThing	bilirubin oxidase activity	Catalysis of the reaction: 2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O.	got7fsn_ti	bilirubin:oxygen oxidoreductase activity|bilirubin oxidase M-1											KEGG_REACTION:R02394|RHEA:20980|MetaCyc:BILIRUBIN-OXIDASE-RXN|EC:1.3.3.5		molecular_function											owl:Class	
GO:0016634	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen.	got7fsn_ti												EC:1.3.3.-		molecular_function											owl:Class	
GO:0048884	biolink:NamedThing	neuromast development	The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.	got7fsn_ti														biological_process											owl:Class	
GO:0060275	biolink:NamedThing	maintenance of stationary phase in response to starvation	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment.	got7fsn_ti														biological_process											owl:Class	
GO:0047155	biolink:NamedThing	3-hydroxymethylcephem carbamoyltransferase activity	Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem.	got7fsn_ti	carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase activity|3'-hydroxymethylcephem-O-carbamoyltransferase activity										GO:0045447	MetaCyc:2.1.3.7-RXN|EC:2.1.3.7		molecular_function											owl:Class	
GO:0016743	biolink:NamedThing	carboxyl- or carbamoyltransferase activity	Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).	got7fsn_ti	carboxyl- and carbamoyltransferase activity											EC:2.1.3.-		molecular_function											owl:Class	
GO:0016201	biolink:NamedThing	synaptic target inhibition	The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.	got7fsn_ti														biological_process											owl:Class	
GO:0004311	biolink:NamedThing	farnesyltranstransferase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.	got7fsn_ti	geranylgeranyl pyrophosphate synthase activity|geranylgeranyl-diphosphate synthase activity|geranylgeranyl pyrophosphate synthetase activity|farnesyltransferase activity|trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity|geranylgeranyl-PP synthetase activity				The catalyzed reaction forms (free) geranylgeranyl diphosphate.  There is no relationship between this activity and protein farnesyltransferase activity, GO:0004660, where the catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein.							KEGG_REACTION:R02061|RHEA:17653|MetaCyc:FARNESYLTRANSTRANSFERASE-RXN|EC:2.5.1.29		molecular_function											owl:Class	
GO:0043586	biolink:NamedThing	tongue development	The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.	got7fsn_ti	lingua development|glossa development													biological_process											owl:Class	
GO:1990190	biolink:NamedThing	peptide-glutamate-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide.	got7fsn_ti							tb	2013-09-11T20:21:25Z						molecular_function											owl:Class	
GO:0021934	biolink:NamedThing	hindbrain tangential cell migration	The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration.	got7fsn_ti	hindbrain neurophilic migration													biological_process											owl:Class	
GO:0021535	biolink:NamedThing	cell migration in hindbrain	The orderly movement of a cell that will reside in the hindbrain.	got7fsn_ti														biological_process											owl:Class	
GO:0044816	biolink:NamedThing	Nsk1-Dlc1 complex	A dimer of Nsk1 (nucleolus spindle kinetochore 1) and the dynein light chain, Dlc1. The dimers form an oligomeric chain structure. Functions in the regulation of kinetochore-microtubule interactions and chromosome segregation.	got7fsn_ti							jl	2013-10-21T14:38:16Z						cellular_component											owl:Class	
GO:0052074	biolink:NamedThing	positive regulation by symbiont of host salicylic acid-mediated defense response	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of host salicylic acid-mediated defense response|up regulation by symbiont of host salicylic acid-mediated defense response|stimulation by symbiont of host salicylic acid-mediated defense response|positive regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|induction by organism of host SA-mediated defense response|up-regulation by symbiont of host salicylic acid-mediated defense response|upregulation by symbiont of host salicylic acid-mediated defense response|positive regulation by organism of host SA-mediated defense response|activation by symbiont of host salicylic acid-mediated defense response										GO:0052272			biological_process											owl:Class	
GO:0085026	biolink:NamedThing	tubovesicular membrane network	A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains.	got7fsn_ti	TVM network|TVN						jl	2010-07-09T03:55:41Z						cellular_component											owl:Class	
GO:0070277	biolink:NamedThing	iodide oxidation	The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons.	got7fsn_ti														biological_process											owl:Class	
GO:0070276	biolink:NamedThing	halogen metabolic process	The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.	got7fsn_ti	halogen metabolism													biological_process											owl:Class	
GO:0047244	biolink:NamedThing	N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity	Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.	got7fsn_ti	N-acetylmannosaminyltransferase activity|uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase activity|UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase activity|UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase activity											EC:2.4.1.187|RHEA:16053|MetaCyc:TEICHOICSYN2-RXN		molecular_function											owl:Class	
GO:0072028	biolink:NamedThing	nephron morphogenesis	The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.	got7fsn_ti							mah	2010-01-25T02:45:52Z						biological_process											owl:Class	
GO:0050041	biolink:NamedThing	lactate aldolase activity	Catalysis of the reaction: (S)-lactate = acetaldehyde + formate.	got7fsn_ti	(S)-lactate acetaldehyde-lyase activity|(S)-lactate acetaldehyde-lyase (formate-forming)|lactate synthase activity											EC:4.1.2.36|RHEA:17909|MetaCyc:LACTATE-ALDOLASE-RXN|KEGG_REACTION:R00753		molecular_function											owl:Class	
GO:0008302	biolink:NamedThing	female germline ring canal formation, actin assembly	Recruitment and organization of actin filaments in female germline ring canals.	got7fsn_ti	ring canal formation, actin assembly|nurse cell ring canal formation, actin assembly|ovarian ring canal formation, actin assembly													biological_process											owl:Class	
GO:0004847	biolink:NamedThing	urea carboxylase activity	Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H(+) + phosphate + urea-1-carboxylate.	got7fsn_ti	urea carboxylase (hydrolyzing) activity|urease (ATP-hydrolysing)|urea amidolyase activity|UALase activity|urea carboxylase (hydrolysing)|urea:carbon-dioxide ligase (ADP-forming)|urease (ATP-hydrolyzing) activity|UCA activity|ATP--urea amidolyase activity											KEGG_REACTION:R00774|EC:6.3.4.6|RHEA:20896|MetaCyc:UREA-CARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0061304	biolink:NamedThing	retinal blood vessel morphogenesis	The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-09-16T09:02:59Z						biological_process											owl:Class	
GO:0070765	biolink:NamedThing	gamma-secretase complex	A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four core subunits; known regulatory subunits include gamma-secretase-activating protein (aka gSAP), TMP1 (aka TMED10), and CD147 antigen (aka basigin). Gamma-secretase cleaves type I transmembrane protein substrates, including the cell surface receptor Notch and the amyloid-beta precursor protein.	got7fsn_ti	CD147-gamma-secretase complex (APH-1a, PS-1, PEN-2, NCT variant)|gamma-secretase complex (APH1B, PSEN2, PSENEN, NCSTN)|gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN)|gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN)|presenilin complex|PS2 complex|PS1 complex|gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN variant)	https://github.com/geneontology/go-ontology/issues/20317					mah	2009-06-29T01:33:19Z						cellular_component											owl:Class	
GO:1990705	biolink:NamedThing	cholangiocyte proliferation	The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water.	got7fsn_ti	hepatoblast proliferation							2015-03-16T23:23:50Z						biological_process											owl:Class	
GO:0050673	biolink:NamedThing	epithelial cell proliferation	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.	got7fsn_ti														biological_process											owl:Class	
GO:0014046	biolink:NamedThing	dopamine secretion	The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.	got7fsn_ti														biological_process											owl:Class	
GO:0018447	biolink:NamedThing	chloral hydrate dehydrogenase activity	Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol.	got7fsn_ti												UM-BBD_enzymeID:e0229		molecular_function											owl:Class	
GO:0047643	biolink:NamedThing	alginate synthase activity	Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1).	got7fsn_ti	mannuronosyl transferase activity|GDP-D-mannuronate:alginate D-mannuronyltransferase activity											EC:2.4.1.33|MetaCyc:ALGINATE-SYNTHASE-RXN|RHEA:46876		molecular_function											owl:Class	
GO:0043502	biolink:NamedThing	regulation of muscle adaptation	Any process that modulates the frequency, rate or extent of muscle adaptation.	got7fsn_ti	regulation of muscle plasticity													biological_process											owl:Class	
GO:0061129	biolink:NamedThing	negative regulation of positive chemotaxis to cAMP by DIF-2	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.	got7fsn_ti							dph	2010-05-17T08:50:33Z						biological_process											owl:Class	
GO:0061125	biolink:NamedThing	negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.	got7fsn_ti							dph	2010-05-17T08:36:55Z						biological_process											owl:Class	
GO:0052735	biolink:NamedThing	tRNA (cytosine-3-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 3-methylcytosine.	got7fsn_ti	S-adenosyl-L-methionine:tRNA cytosine-3-methyltransferase activity|transfer ribonucleate cytosine 3-methyltransferase activity|tRNA cytosine 3-methyltransferase activity|S-adenosyl-L-methionine:tRNA (cytosine-3-)-methyltransferase activity|tRNA (cytosine 3)-methyltransferase activity|tRNA cytosine-3-methyltransferase activity													molecular_function											owl:Class	
GO:0016427	biolink:NamedThing	tRNA (cytosine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.	got7fsn_ti														molecular_function											owl:Class	
GO:0004318	biolink:NamedThing	enoyl-[acyl-carrier-protein] reductase (NADH) activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.	got7fsn_ti	enoyl-[acyl-carrier protein] reductase (NADH) activity|NADH-enoyl acyl carrier protein reductase activity|acyl-acyl-carrier-protein:NAD+ oxidoreductase|NADH-specific enoyl-ACP reductase activity|enoyl-ACP reductase (NADH) activity|enoyl-acyl-carrier-protein reductase (NADH)											MetaCyc:ENOYL-ACP-REDUCT-NADH-RXN|EC:1.3.1.9		molecular_function											owl:Class	
GO:0031286	biolink:NamedThing	negative regulation of sorocarp stalk cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	down regulation of stalk cell differentiation|downregulation of stalk cell differentiation|down-regulation of stalk cell differentiation|negative regulation of stalk cell differentiation|inhibition of stalk cell differentiation													biological_process											owl:Class	
GO:0075262	biolink:NamedThing	negative regulation of spore-bearing organ development	Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.	got7fsn_ti														biological_process											owl:Class	
GO:0048555	biolink:NamedThing	generative cell nucleus	The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells.	got7fsn_ti	sperm cell nucleus|male germ cell nucleus													cellular_component											owl:Class	
GO:0050279	biolink:NamedThing	sepiapterin deaminase activity	Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3.	got7fsn_ti	sepiapterin aminohydrolase activity											RHEA:14025|EC:3.5.4.24|MetaCyc:SEPIAPTERIN-DEAMINASE-RXN		molecular_function											owl:Class	
GO:0004467	biolink:NamedThing	long-chain fatty acid-CoA ligase activity	Catalysis of the reaction: ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain fatty acid activation|long-chain acyl-coenzyme A synthetase activity|acyl-CoA synthetase activity|thiokinase|long-chain-fatty-acid-CoA ligase activity|acyl-activating enzyme activity|LCFA synthetase activity|pristanoyl-CoA synthetase|long-chain fatty acyl coenzyme A synthetase activity|acyl-CoA ligase activity|long-chain acyl CoA synthetase activity|long chain fatty acyl-CoA synthetase activity|long-chain-fatty-acyl-CoA synthetase activity|stearoyl-CoA synthetase|long-chain acyl-CoA synthetase activity|fatty acid thiokinase (long-chain) activity|lignoceroyl-CoA synthase activity	https://github.com/geneontology/go-ontology/issues/20462|https://github.com/geneontology/go-ontology/issues/18967									GO:0003996	RHEA:15421|Reactome:R-HSA-193711|Reactome:R-HSA-192137|Reactome:R-HSA-5696004|Reactome:R-HSA-2046085|Reactome:R-HSA-2046098|MetaCyc:PWY-5143|Reactome:R-HSA-201035|Reactome:R-HSA-193743|Reactome:R-HSA-193766|Reactome:R-HSA-548843|MetaCyc:ACYLCOASYN-RXN|Reactome:R-HSA-193727|Reactome:R-HSA-159425|EC:6.2.1.3|Reactome:R-HSA-193407|Reactome:R-HSA-193424|UM-BBD_enzymeID:e0025|Reactome:R-HSA-193401		molecular_function											owl:Class	
GO:0015645	biolink:NamedThing	fatty acid ligase activity	Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.	got7fsn_ti	fatty acid CoA ligase activity|fatty acyl-coenzyme A synthetase activity|fatty-acid ligase activity													molecular_function											owl:Class	
GO:0007228	biolink:NamedThing	positive regulation of hh target transcription factor activity	Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.	got7fsn_ti	activation of hh target transcription factor|positive regulation of hedgehog target transcription factor													biological_process											owl:Class	
GO:0140429	biolink:NamedThing	positive regulation of mitotic sister chromatid biorientation	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed.	got7fsn_ti	repair of mitotic merotelic kinetochore attachment defects|correction of merotelic kinetochore attachment, mitotic|correction of syntelic kinetochore attachment, mitotic|repair of mitotic merotelic kinetochore attachment defect|repair of mitotic mono-orientation defect|correction of mono-orientation defects|repair of mitotic mono-orientation defects	https://github.com/geneontology/go-ontology/issues/18815					jl	2015-01-05T16:54:39Z			GO:1990598|GO:0098783			biological_process											owl:Class	
GO:0140273	biolink:NamedThing	repair of mitotic kinetochore microtubule attachment defect	The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected.	got7fsn_ti	correction of mitotic kinetochore microtubule attachment defects|repair of mitotic kinetochore microtubule attachment defects						pg	2018-10-01T11:29:24Z						biological_process											owl:Class	
GO:0052003	biolink:NamedThing	suppression by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of host SA-mediated defense response|down-regulation by symbiont of host salicylic acid-mediated defense response|inhibition by symbiont of host salicylic acid-mediated defense response|suppression of host SA mediated defense response|negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|downregulation by symbiont of host salicylic acid-mediated defense response|down-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|down regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative modulation by organism of defense-related host SA-mediated signal transduction pathway|negative regulation by symbiont of host salicylic acid-mediated defense response|downregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|down regulation by symbiont of host salicylic acid-mediated defense response|negative regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|negative regulation by organism of defense-related salicylic acid-mediated signal transduction pathway of other organism involved in symbiotic interaction|negative modulation by organism of defense-related host salicylic acid-mediated signal transduction pathway|negative regulation by organism of defense-related host SA-mediated signal transduction pathway|suppression by organism of host salicylic acid-mediated defense response|inhibition by symbiont of defense-related host salicylic acid-mediated signal transduction pathway										GO:0052004|GO:0052252|GO:0052253			biological_process											owl:Class	
GO:0019553	biolink:NamedThing	glutamate catabolic process via L-citramalate	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate.	got7fsn_ti	glutamate breakdown via L-citramalate|glutamate degradation via L-citramalate											MetaCyc:GLUDEG-II-PWY		biological_process											owl:Class	
GO:0006538	biolink:NamedThing	glutamate catabolic process	The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid.	got7fsn_ti	glutamate deamidation|glutamic acid catabolism|glutamic acid catabolic process|glutamate catabolism|glutamate degradation|glutamate breakdown										GO:0019459			biological_process											owl:Class	
GO:0034008	biolink:NamedThing	R-linalool synthase activity	Catalysis of the reaction: geranyl diphosphate + H(2)O = (R)-linalool + diphosphate.	got7fsn_ti	(-)-3R-linalool synthase activity|(3R)-linalool synthase activity|geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming] activity											KEGG_REACTION:R07632|MetaCyc:4.2.3.26-RXN|EC:4.2.3.26|RHEA:15809		molecular_function											owl:Class	
GO:0000497	biolink:NamedThing	DNA template activity	Binding to nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.	got7fsn_ti	base pairing with DNA				Note that with respect to annotation, "base pairing" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with DNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function.									molecular_function											owl:Class	
GO:0015778	biolink:NamedThing	hexuronide transport	The directed movement of hexuronide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate.	got7fsn_ti														biological_process											owl:Class	
GO:0008643	biolink:NamedThing	carbohydrate transport	The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.	got7fsn_ti	sugar transport										GO:0008644|GO:0006861			biological_process											owl:Class	
GO:0036421	biolink:NamedThing	extrinsic component of external side of mycolate outer membrane	The component of mycolate membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to external side of MOM|extrinsic to external side of mycolate outer membrane|extrinsic to external side of mycomembrane						bf	2013-09-05T20:23:45Z						cellular_component											owl:Class	
GO:0031242	biolink:NamedThing	extrinsic component of external side of cell outer membrane	The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to external side of cell outer membrane|extrinsic to external leaflet of cell outer membrane|extrinsic to external side of outer membrane													cellular_component											owl:Class	
GO:0030851	biolink:NamedThing	granulocyte differentiation	The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.	got7fsn_ti	granulocyte cell differentiation													biological_process											owl:Class	
GO:0006370	biolink:NamedThing	7-methylguanosine mRNA capping	Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.	got7fsn_ti	5' mRNA capping|mRNA capping|5'-end mRNA processing|5'-end processing|5' end capping													biological_process											owl:Class	
GO:0009452	biolink:NamedThing	7-methylguanosine RNA capping	The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript.	got7fsn_ti	m(7)G RNA capping|RNA capping													biological_process											owl:Class	
GO:0061379	biolink:NamedThing	inferior colliculus development	The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.	got7fsn_ti							dph	2010-11-09T09:49:24Z						biological_process											owl:Class	
GO:0001830	biolink:NamedThing	trophectodermal cell fate commitment	The cell fate commitment of precursor cells that will become trophectoderm cells.	got7fsn_ti	trophectoderm cell fate commitment				See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.									biological_process											owl:Class	
GO:0010289	biolink:NamedThing	homogalacturonan biosynthetic process	The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.	got7fsn_ti												MetaCyc:PWY-1061		biological_process											owl:Class	
GO:0052325	biolink:NamedThing	cell wall pectin biosynthetic process	The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.	got7fsn_ti	cell wall pectin biosynthesis|pectin biosynthesis during cell wall organization and biogenesis													biological_process											owl:Class	
GO:0018201	biolink:NamedThing	peptidyl-glycine modification	The modification of peptidyl-glycine.	got7fsn_ti														biological_process											owl:Class	
GO:0034985	biolink:NamedThing	Ecsit-NDUFAF1 complex	Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.	got7fsn_ti														cellular_component											owl:Class	
GO:0045251	biolink:NamedThing	electron transfer flavoprotein complex	A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system.	got7fsn_ti	ETF complex													cellular_component											owl:Class	
GO:0019203	biolink:NamedThing	carbohydrate phosphatase activity	Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate.	got7fsn_ti												Reactome:R-HSA-3781011|Reactome:R-HSA-3791349|Reactome:R-HSA-3781018		molecular_function											owl:Class	
GO:0007259	biolink:NamedThing	receptor signaling pathway via JAK-STAT	Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.	got7fsn_ti	JAK-STAT cascade|JAK-STAT signal transduction											Wikipedia:JAK-STAT_signaling_pathway		biological_process											owl:Class	
GO:0097696	biolink:NamedThing	receptor signaling pathway via STAT	An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.	got7fsn_ti	kinase activated-STAT cascade|kinase-STAT cascade|STAT signalling pathway				In most species, STAT proteins are activated by members of the JAK (Janus Activated Kinase) family of tyrosine kinases; the term GO:0007259 'JAK-STAT cascade' describes this specificity. In other cases, such as D. discoideum, no JAK orthologs are known, and STAT proteins are activated by tyrosine kinase-like proteins.		pr	2015-12-22T10:40:14Z						biological_process											owl:Class	
GO:0046463	biolink:NamedThing	acylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.	got7fsn_ti	acylglycerol formation|acylglycerol synthesis|acylglycerol anabolism|acylglycerol biosynthesis													biological_process											owl:Class	
GO:0046460	biolink:NamedThing	neutral lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.	got7fsn_ti	neutral lipid formation|neutral lipid biosynthesis|neutral lipid anabolism|neutral lipid synthesis													biological_process											owl:Class	
GO:0010026	biolink:NamedThing	trichome differentiation	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	trichome cell differentiation										GO:0048271			biological_process											owl:Class	
GO:0040012	biolink:NamedThing	regulation of locomotion	Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.	got7fsn_ti														biological_process											owl:Class	
GO:0044842	biolink:NamedThing	gut granule lumen	The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.	got7fsn_ti							jl	2014-03-25T12:02:32Z						cellular_component											owl:Class	
GO:0050433	biolink:NamedThing	regulation of catecholamine secretion	Any process that modulates the frequency, rate or extent of the regulated release of catecholamines.	got7fsn_ti														biological_process											owl:Class	
GO:0006089	biolink:NamedThing	lactate metabolic process	The chemical reactions and pathways involving lactate, the anion of lactic acid.	got7fsn_ti	2-hydroxypropanoate metabolism|2-hydroxypropanoate metabolic process|alpha-hydroxypropionate metabolism|lactate metabolism|alpha-hydroxypropionate metabolic process													biological_process											owl:Class	
GO:0006929	biolink:NamedThing	substrate-dependent cell migration	The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.	got7fsn_ti	substrate-bound cell migration													biological_process											owl:Class	
GO:0047768	biolink:NamedThing	carboxy-cis,cis-muconate cyclase activity	Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate.	got7fsn_ti	3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)|3-carboxymuconate cyclase activity|3-carboxy-cis,cis-muconate lactonizing enzyme activity											MetaCyc:CARBOXY-CISCIS-MUCONATE-CYCLASE-RXN|RHEA:14977|EC:5.5.1.5|KEGG_REACTION:R03308		molecular_function											owl:Class	
GO:0009975	biolink:NamedThing	cyclase activity	Catalysis of a ring closure reaction.	got7fsn_ti														molecular_function											owl:Class	
GO:0071932	biolink:NamedThing	replication fork reversal	Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.	got7fsn_ti							mah	2010-09-29T02:34:22Z						biological_process											owl:Class	
GO:0102806	biolink:NamedThing	4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6''-O-acyltransferase activity	Catalysis of the reaction: 4-coumaryl-CoA + cyanin betaine <=> shisonin + coenzyme A.	got7fsn_ti												MetaCyc:RXN-8170		molecular_function											owl:Class	
GO:0031769	biolink:NamedThing	glucagon receptor binding	Binding to a glucagon receptor.	got7fsn_ti	glucagon receptor ligand													molecular_function											owl:Class	
GO:0008923	biolink:NamedThing	lysine decarboxylase activity	Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2).	got7fsn_ti	L-lysine carboxy-lyase (cadaverine-forming)|L-lysine carboxy-lyase activity											MetaCyc:LYSDECARBOX-RXN|EC:4.1.1.18|MetaCyc:PWY0-461|RHEA:22352|KEGG_REACTION:R00462		molecular_function											owl:Class	
GO:0035005	biolink:NamedThing	1-phosphatidylinositol-4-phosphate 3-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+).	got7fsn_ti	C2-domain-containing phosphoinositide 3-kinase activity|phosphatidylinositol 3-kinase activity, class II|phosphatidylinositol-4-phosphate 3-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase activity|phosphatidylinositol 3-kinase activity, class I|phosphatidylinositol 3-kinase, class I, catalyst activity|type II phosphoinositide 3-kinase activity											Reactome:R-HSA-1675928|Reactome:R-HSA-1676109|MetaCyc:2.7.1.154-RXN|Reactome:R-HSA-8868072|RHEA:18373|Reactome:R-HSA-1676206|EC:2.7.1.154|KEGG_REACTION:R05795		molecular_function											owl:Class	
GO:0035004	biolink:NamedThing	phosphatidylinositol 3-kinase activity	Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.	got7fsn_ti	phosphoinositide 3-kinase activity											Reactome:R-HSA-2045911|Reactome:R-HSA-9670433|Wikipedia:Phosphoinositide_3-kinase|Reactome:R-HSA-1433514|Reactome:R-HSA-9028519		molecular_function											owl:Class	
GO:0009289	biolink:NamedThing	pilus	A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.	got7fsn_ti	fimbria|fimbrium|fimbriae|pili											Wikipedia:Pilus		cellular_component											owl:Class	
GO:0042995	biolink:NamedThing	cell projection	A prolongation or process extending from a cell, e.g. a flagellum or axon.	got7fsn_ti	cellular process|cellular projection|cell process													cellular_component											owl:Class	
GO:0035042	biolink:NamedThing	fertilization, exchange of chromosomal proteins	Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity.	got7fsn_ti	sperm-specific histone replacement|sperm-specific histone exchange													biological_process											owl:Class	
GO:0043486	biolink:NamedThing	histone exchange	The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.	got7fsn_ti	histone replacement|histone chaperone				Note that this term also includes the exchange of sperm-specific histones or protamines with histones, occurring during spermatogenesis and fertilization.									biological_process											owl:Class	
GO:0071200	biolink:NamedThing	Kv4.2-DPP6 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.	got7fsn_ti	Kv4.2-DPPX channel complex						mah	2009-11-23T05:18:31Z				CORUM:603		cellular_component											owl:Class	
GO:0004741	biolink:NamedThing	[pyruvate dehydrogenase (lipoamide)] phosphatase activity	Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate.	got7fsn_ti	pyruvate dehydrogenase (lipoamide)-phosphatase activity|pyruvate dehydrogenase (lipoamide) phosphatase activity|phosphopyruvate dehydrogenase phosphatase activity|pyruvate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity|[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic catalyst activity|pyruvate dehydrogenase phosphatase activity										GO:0019906	Reactome:R-HSA-204169|RHEA:12669|MetaCyc:3.1.3.43-RXN|EC:3.1.3.43		molecular_function											owl:Class	
GO:0071206	biolink:NamedThing	establishment of protein localization to juxtaparanode region of axon	The directed movement of a protein to the juxtaparanode region of an axon.	got7fsn_ti	establishment of protein localisation to juxtaparanode region of axon						mah	2009-11-25T01:15:23Z						biological_process											owl:Class	
GO:0047538	biolink:NamedThing	2-carboxy-D-arabinitol-1-phosphatase activity	Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H(2)O = 2-carboxy-D-arabinitol + phosphate.	got7fsn_ti	2-carboxyarabinitol 1-phosphatase activity|2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase activity|2-carboxy-D-arabinitol 1-phosphate phosphohydrolase activity											RHEA:17837|KEGG_REACTION:R04167|EC:3.1.3.63|MetaCyc:2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0060113	biolink:NamedThing	inner ear receptor cell differentiation	The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.	got7fsn_ti	inner ear hair cell differentiation													biological_process											owl:Class	
GO:0042490	biolink:NamedThing	mechanoreceptor differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0034681	biolink:NamedThing	integrin alpha11-beta1 complex	An integrin complex that comprises one alpha11 subunit and one beta1 subunit.	got7fsn_ti	ITGA11-ITGB1 complex|alpha11-beta1 integrin complex													cellular_component											owl:Class	
GO:0099008	biolink:NamedThing	viral entry via permeabilization of inner membrane	The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane.  In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane.	got7fsn_ti	viral penetration via permeabilization of host membrane											VZ:985		biological_process											owl:Class	
GO:0140267	biolink:NamedThing	viral entry via permeabilization of host membrane	The entry of a virus into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration capsid protein. Results in release of the virus contents into the host cell cytoplasm.	got7fsn_ti							pg	2018-09-25T14:33:03Z						biological_process											owl:Class	
GO:0050048	biolink:NamedThing	L-leucine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.	got7fsn_ti	leucine-alpha-ketoglutarate transaminase activity|leucine 2-oxoglutarate transaminase activity|leucine aminotransferase activity|leucine transaminase activity|L-leucine aminotransferase activity											EC:2.6.1.6|RHEA:18321|MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0051480	biolink:NamedThing	regulation of cytosolic calcium ion concentration	Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.	got7fsn_ti	regulation of calcium ion concentration in cytoplasm|regulation of cytosolic calcium ion concentration|calcium ion homeostasis in cytoplasm|cytoplasmic calcium ion homeostasis|cytosolic calcium ion concentration regulation|regulation of calcium ion concentration in cytosol|cytoplasmic calcium ion concentration regulation|calcium ion homeostasis in cytosol|regulation of cytoplasmic calcium ion concentration													biological_process											owl:Class	
GO:0031851	biolink:NamedThing	kappa-type opioid receptor binding	Binding to a kappa-type opioid receptor.	got7fsn_ti	dynorphin receptor binding|kappa-type opioid receptor ligand													molecular_function											owl:Class	
GO:0018303	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulphide											RESID:AA0285		biological_process											owl:Class	
GO:0051173	biolink:NamedThing	positive regulation of nitrogen compound metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.	got7fsn_ti	positive regulation of nitrogen metabolic process|activation of nitrogen metabolic process|up regulation of nitrogen metabolic process|upregulation of nitrogen metabolic process|up-regulation of nitrogen metabolic process|stimulation of nitrogen metabolic process|positive regulation of nitrogen metabolism													biological_process											owl:Class	
GO:0001846	biolink:NamedThing	opsonin binding	Binding to an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material.	got7fsn_ti					Note that an opsonin is a blood serum protein or fragment which when deposited on the surface of a bacteria, virus, immune complex, or other particulate material acts a signal for phagocytosis to cells bearing the appropriate receptors. Not all complement components or fragments and not all antibodies have opsonic properties.									molecular_function											owl:Class	
GO:0051551	biolink:NamedThing	aurone biosynthetic process	The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments.	got7fsn_ti	benzalcoumaran-3-one biosynthetic process|benzalcoumaran-3-one biosynthesis													biological_process											owl:Class	
GO:0009813	biolink:NamedThing	flavonoid biosynthetic process	The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.	got7fsn_ti	flavonoid formation|flavonoid biosynthesis|flavonoid anabolism|flavonoid synthesis											Wikipedia:Flavonoid|MetaCyc:PWY1F-FLAVSYN		biological_process											owl:Class	
GO:0051992	biolink:NamedThing	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol.	got7fsn_ti					Note that EC classifies 'UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity ; GO:0051992' and 'phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963' under the same EC number, EC:2.7.8.13.		ai	2010-07-06T12:10:01Z				MetaCyc:PHOSNACMURPENTATRANS-RXN|RHEA:28386|EC:2.7.8.13		molecular_function											owl:Class	
GO:0019072	biolink:NamedThing	viral genome packaging	The encapsulation of the viral genome within the capsid.	got7fsn_ti														biological_process											owl:Class	
GO:0008418	biolink:NamedThing	protein-N-terminal asparagine amidohydrolase activity	Catalysis of the reaction: protein-L-asparagine + H2O = protein-L-aspartate + NH3. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0045475	biolink:NamedThing	locomotor rhythm	The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.	got7fsn_ti	circadian locomotor activity rhythm													biological_process											owl:Class	
GO:0046703	biolink:NamedThing	natural killer cell lectin-like receptor binding	Binding to a lectin-like natural killer cell receptor.	got7fsn_ti	KLRC4 receptor binding|NKG2D receptor binding|NK cell lectin-like receptor binding													molecular_function											owl:Class	
GO:0050287	biolink:NamedThing	sorbose 5-dehydrogenase (NADP+) activity	Catalysis of the reaction: L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH.	got7fsn_ti	reduced nicotinamide adenine dinucleotide phosphate-linked reductase activity|sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|5-keto-D-fructose reductase activity|5-ketofructose reductase activity|L-sorbose:NADP+ 5-oxidoreductase activity											EC:1.1.1.123|RHEA:15001|KEGG_REACTION:R01694|MetaCyc:SORBOSE-5-DEHYDROGENASE-NADP+-RXN		molecular_function											owl:Class	
GO:0072134	biolink:NamedThing	nephrogenic mesenchyme morphogenesis	The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.	got7fsn_ti							mah	2010-02-22T02:21:16Z						biological_process											owl:Class	
GO:0140301	biolink:NamedThing	pollen-stigma interaction	The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae.	got7fsn_ti							pg	2019-02-22T13:58:21Z						biological_process											owl:Class	
GO:0009875	biolink:NamedThing	pollen-pistil interaction	The interaction between a pollen grain and pistil.	got7fsn_ti	pollen-gynoecium interaction													biological_process											owl:Class	
GO:0060519	biolink:NamedThing	cell adhesion involved in prostatic bud elongation	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud.	got7fsn_ti														biological_process											owl:Class	
GO:0007155	biolink:NamedThing	cell adhesion	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.	got7fsn_ti	single organism cell adhesion|cell adhesion molecule activity						dos	2014-04-15T15:59:10Z			GO:0098602	Wikipedia:Cell_adhesion		biological_process											owl:Class	
GO:0062180	biolink:NamedThing	25-hydroxycholecalciferol-23-hydroxylase activity	Catalysis of the reaction: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin].	got7fsn_ti							dph	2019-11-26T17:12:22Z				RHEA:46616		molecular_function											owl:Class	
GO:0062179	biolink:NamedThing	vitamin D 23-hydroxylase activity	Catalysis of the hydroxylation of C-23 of any form of vitamin D.	got7fsn_ti							dph	2019-11-26T17:10:29Z						molecular_function											owl:Class	
GO:0031123	biolink:NamedThing	RNA 3'-end processing	Any process involved in forming the mature 3' end of an RNA molecule.	got7fsn_ti	RNA 3' end processing													biological_process											owl:Class	
GO:0047376	biolink:NamedThing	all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity	Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.	got7fsn_ti	retinyl-palmitate palmitohydrolase activity|all-trans-retinyl-palmitate acylhydrolase activity|all-trans-retinyl-palmitate hydrolase activity											Reactome:R-HSA-2404140|KEGG_REACTION:R02368|MetaCyc:3.1.1.64-RXN|RHEA:13933|Reactome:R-HSA-2429643		molecular_function											owl:Class	
GO:0042724	biolink:NamedThing	thiamine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds.	got7fsn_ti	thiamin and derivative biosynthesis|vitamin B1 and derivative biosynthesis|thiamine and derivative biosynthesis|thiamine-containing compound anabolism|vitamin B1 and derivative biosynthetic process|thiamine-containing compound synthesis|thiamin-containing compound biosynthetic process|thiamine-containing compound formation|thiamin and derivative biosynthetic process|thiamine-containing compound biosynthesis|thiamine and derivative biosynthetic process													biological_process											owl:Class	
GO:0047235	biolink:NamedThing	sucrose 6F-alpha-galactotransferase activity	Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP.	got7fsn_ti	UDPgalactose:sucrose 6F-alpha-D-galactosyltransferase activity|UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase activity|uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase activity|UDPgalactose:sucrose 6fru-alpha-galactosyltransferase activity|sucrose 6(F)-alpha-galactosyltransferase activity|sucrose 6F-alpha-galactosyltransferase activity											MetaCyc:2.4.1.167-RXN|EC:2.4.1.167|RHEA:10088		molecular_function											owl:Class	
GO:0031003	biolink:NamedThing	actin tubule	A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together.	got7fsn_ti														cellular_component											owl:Class	
GO:0032432	biolink:NamedThing	actin filament bundle	An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.	got7fsn_ti	actin cable										GO:0030482|GO:0000141			cellular_component											owl:Class	
GO:0033726	biolink:NamedThing	aldehyde ferredoxin oxidoreductase activity	Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.	got7fsn_ti	tungsten-containing aldehyde ferredoxin oxidoreductase activity|aldehyde:ferredoxin oxidoreductase activity|AOR											EC:1.2.7.5|MetaCyc:1.2.7.5-RXN|RHEA:16421		molecular_function											owl:Class	
GO:0016625	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	got7fsn_ti	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulphur protein as acceptor											EC:1.2.7.-		molecular_function											owl:Class	
GO:0061817	biolink:NamedThing	endoplasmic reticulum-plasma membrane tethering	The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers.	got7fsn_ti	ER-plasma membrane tethering						dph	2016-12-05T14:43:58Z						biological_process											owl:Class	
GO:0022810	biolink:NamedThing	membrane potential driven uniporter activity	Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.	got7fsn_ti	porter													molecular_function											owl:Class	
GO:0070469	biolink:NamedThing	respirasome	The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.	got7fsn_ti	respiratory chain|membrane electron transport chain	https://github.com/geneontology/go-ontology/issues/12846												cellular_component											owl:Class	
GO:0072076	biolink:NamedThing	nephrogenic mesenchyme development	The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.	got7fsn_ti							mah	2010-01-25T04:40:44Z						biological_process											owl:Class	
GO:0072074	biolink:NamedThing	kidney mesenchyme development	The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.	got7fsn_ti							mah	2010-01-25T04:39:04Z						biological_process											owl:Class	
GO:0098857	biolink:NamedThing	membrane microdomain	A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.	got7fsn_ti														cellular_component											owl:Class	
GO:0070121	biolink:NamedThing	Kupffer's vesicle development	The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.	got7fsn_ti	KV development													biological_process											owl:Class	
GO:0004333	biolink:NamedThing	fumarate hydratase activity	Catalysis of the reaction: (S)-malate = fumarate + H(2)O.	got7fsn_ti	(S)-malate hydro-lyase activity|fumarase activity|L-malate hydro-lyase activity|(S)-malate hydro-lyase (fumarate-forming)											Reactome:R-HSA-451033|MetaCyc:FUMHYDR-RXN|RHEA:12460|Reactome:R-HSA-70982|EC:4.2.1.2|KEGG_REACTION:R01082		molecular_function											owl:Class	
GO:0071050	biolink:NamedThing	sno(s)RNA polyadenylation	The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA class molecule (referred to as an sRNA in Archaea). In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation.	got7fsn_ti	sRNA polyadenylation|snoRNA polyadenylation	https://github.com/geneontology/go-ontology/issues/20416					krc	2009-08-25T03:33:44Z						biological_process											owl:Class	
GO:0140069	biolink:NamedThing	histone butyryltransferase activity	Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone.	got7fsn_ti							pg	2017-07-20T16:56:33Z						molecular_function											owl:Class	
GO:0008297	biolink:NamedThing	single-stranded DNA exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule.	got7fsn_ti	ssDNA-specific exodeoxyribonuclease activity|single-stranded DNA specific exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0010407	biolink:NamedThing	non-classical arabinogalactan protein metabolic process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains.	got7fsn_ti	non-classical arabinogalactan protein metabolism													biological_process											owl:Class	
GO:0010405	biolink:NamedThing	arabinogalactan protein metabolic process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures.	got7fsn_ti	arabinogalactan protein metabolism													biological_process											owl:Class	
GO:0030785	biolink:NamedThing	[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine.	got7fsn_ti	S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity|RuBisCO methyltransferase activity|RuBisCO LSMT activity|ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity|ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase activity|ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity|S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity											MetaCyc:2.1.1.127-RXN|EC:2.1.1.127|RHEA:50996		molecular_function											owl:Class	
GO:0005850	biolink:NamedThing	eukaryotic translation initiation factor 2 complex	Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.	got7fsn_ti	eIF-2|eIF2											Wikipedia:EIF-2		cellular_component											owl:Class	
GO:0006417	biolink:NamedThing	regulation of translation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.	got7fsn_ti	regulation of protein biosynthesis|regulation of protein formation|regulation of protein anabolism|regulation of protein synthesis										GO:0006445			biological_process											owl:Class	
GO:0010608	biolink:NamedThing	posttranscriptional regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0031483	biolink:NamedThing	myosin XIII complex	A myosin complex containing one or more class XIII myosin heavy chains and associated light chains.	got7fsn_ti														cellular_component											owl:Class	
GO:0007486	biolink:NamedThing	imaginal disc-derived female genitalia development	The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.	got7fsn_ti	female genital development													biological_process											owl:Class	
GO:0033734	biolink:NamedThing	(R)-benzylsuccinyl-CoA dehydrogenase activity	Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.	got7fsn_ti	BbsG|(R)-benzylsuccinyl-CoA:acceptor oxidoreductase activity|(R)-benzylsuccinyl-CoA:(acceptor) oxidoreductase activity											RHEA:20876|EC:1.3.8.3|UM-BBD_reactionID:r0330		molecular_function											owl:Class	
GO:0046883	biolink:NamedThing	regulation of hormone secretion	Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0009086	biolink:NamedThing	methionine biosynthetic process	The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.	got7fsn_ti	methionine formation|methionine synthesis|methionine anabolism|methionine biosynthesis													biological_process											owl:Class	
GO:0009067	biolink:NamedThing	aspartate family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.	got7fsn_ti	aspartate family amino acid anabolism|aspartate family amino acid biosynthesis|aspartate family amino acid synthesis|aspartate family amino acid formation													biological_process											owl:Class	
GO:1901135	biolink:NamedThing	carbohydrate derivative metabolic process	The chemical reactions and pathways involving carbohydrate derivative.	got7fsn_ti	carbohydrate derivative metabolism						bf	2012-07-12T04:05:09Z						biological_process											owl:Class	
GO:0040038	biolink:NamedThing	polar body extrusion after meiotic divisions	The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes.	got7fsn_ti														biological_process											owl:Class	
GO:0033206	biolink:NamedThing	meiotic cytokinesis	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells.	got7fsn_ti	cytokinesis after meiosis													biological_process											owl:Class	
GO:0010582	biolink:NamedThing	floral meristem determinacy	The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).	got7fsn_ti														biological_process											owl:Class	
GO:0010022	biolink:NamedThing	meristem determinacy	The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).	got7fsn_ti														biological_process											owl:Class	
GO:0099127	biolink:NamedThing	envenomation resulting in positive regulation of argininosuccinate synthase activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of the cytosolic argininosuccinate synthase in the bitten organism.	got7fsn_ti														biological_process											owl:Class	
GO:0080183	biolink:NamedThing	response to photooxidative stress	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.	got7fsn_ti							dhl	2011-08-10T04:26:11Z						biological_process											owl:Class	
GO:0003224	biolink:NamedThing	left ventricular compact myocardium morphogenesis	The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.	got7fsn_ti							dph	2009-10-13T10:43:36Z						biological_process											owl:Class	
GO:0003223	biolink:NamedThing	ventricular compact myocardium morphogenesis	The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.	got7fsn_ti							dph	2009-10-13T10:34:21Z						biological_process											owl:Class	
GO:0001069	biolink:NamedThing	regulatory region RNA binding	Binding to a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.	got7fsn_ti							krc	2010-10-21T04:17:01Z						molecular_function											owl:Class	
GO:0060346	biolink:NamedThing	bone trabecula formation	The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.	got7fsn_ti	skeletal trabecula biogenesis|skeletal trabecula formation|bone trabeculation|skeletal trabeculation|bone trabecula biogenesis													biological_process											owl:Class	
GO:0048236	biolink:NamedThing	plant-type sporogenesis	The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes.	got7fsn_ti	plant spore formation													biological_process											owl:Class	
GO:0051321	biolink:NamedThing	meiotic cell cycle	Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.	got7fsn_ti	meiosis				Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.						GO:0007126	Wikipedia:Meiosis		biological_process											owl:Class	
GO:0090122	biolink:NamedThing	cholesterol ester hydrolysis involved in cholesterol transport	The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.	got7fsn_ti							tb	2009-12-07T01:06:54Z						biological_process											owl:Class	
GO:0004767	biolink:NamedThing	sphingomyelin phosphodiesterase activity	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+).	got7fsn_ti	sphingomyelinase activity|sphingomyelin cholinephosphohydrolase activity										GO:0030231|GO:0030230	Reactome:R-HSA-1606273|RHEA:19253|MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-RXN|Reactome:R-HSA-1606288|KEGG_REACTION:R02541|Reactome:R-HSA-1640164|Reactome:R-HSA-1605797|EC:3.1.4.12|Reactome:R-HSA-193706		molecular_function											owl:Class	
GO:0001098	biolink:NamedThing	basal transcription machinery binding	Binding to a component of the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.	got7fsn_ti					Note that the definition of basal, or general, transcription factors has typically been done at a small number of well characterized activator-independent promoters. At an activator-dependent promoter, one or more additional factors are generally required in addition to the basal factors.		krc	2010-11-24T12:50:49Z						molecular_function											owl:Class	
GO:0004362	biolink:NamedThing	glutathione-disulfide reductase (NADPH) activity	Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.	got7fsn_ti	GSSG reductase activity|GSH reductase activity|oxidized glutathione reduction|glutathione:NADP+ oxidoreductase activity|glutathione reductase activity|NADPH:oxidized-glutathione oxidoreductase activity|glutathione-disulfide reductase activity|NADPH-GSSG reductase activity|NADPH-glutathione reductase activity|glutathione-disulphide reductase activity|glutathione S-reductase activity	glutathione-disulfide reductase activity			Note that this function was formerly EC:1.6.4.2.							Reactome:R-HSA-71682|RHEA:11740|MetaCyc:GLUTATHIONE-REDUCT-NADPH-RXN|Reactome:R-HSA-3323079|EC:1.8.1.7		molecular_function											owl:Class	
GO:0016209	biolink:NamedThing	antioxidant activity	Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.	got7fsn_ti														molecular_function											owl:Class	
GO:0009785	biolink:NamedThing	blue light signaling pathway	The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.	got7fsn_ti	blue light signalling pathway													biological_process											owl:Class	
GO:0071078	biolink:NamedThing	fibronectin-tissue transglutaminase complex	A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.	got7fsn_ti	FN-TGM2 complex						mah	2009-11-06T04:42:22Z						cellular_component											owl:Class	
GO:0102702	biolink:NamedThing	2-carene synthase activity	Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-5122		molecular_function											owl:Class	
GO:1990646	biolink:NamedThing	cellular response to prolactin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus.	got7fsn_ti							sl	2015-02-18T16:53:11Z						biological_process											owl:Class	
GO:1990637	biolink:NamedThing	response to prolactin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation.	got7fsn_ti							sl	2015-02-10T23:47:11Z						biological_process											owl:Class	
GO:0018401	biolink:NamedThing	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase.	got7fsn_ti					See also the molecular function term 'procollagen-proline 4-dioxygenase activity ; GO:0004656'.							RESID:AA0030		biological_process											owl:Class	
GO:0033518	biolink:NamedThing	myo-inositol hexakisphosphate dephosphorylation	The process of removing one or more phosphate group from myo-inositol hexakisphosphate.	got7fsn_ti	phytate dephosphorylation											MetaCyc:PWY-4781|MetaCyc:PWY-4702		biological_process											owl:Class	
GO:0046855	biolink:NamedThing	inositol phosphate dephosphorylation	The process of removing a phosphate group from any mono- or polyphosphorylated inositol.	got7fsn_ti	myo-inositol phosphate dephosphorylation													biological_process											owl:Class	
GO:0102214	biolink:NamedThing	omega-hydroxy fatty acyl-CoA synthetase activity	Catalysis of the reaction: coenzyme A + ATP + an omega-hydroxy fatty acid = diphosphoric acid + AMP + a omega-hydroxyacyl-CoA.	got7fsn_ti												MetaCyc:RXN-12185		molecular_function											owl:Class	
GO:0018002	biolink:NamedThing	N-terminal peptidyl-glutamic acid acetylation	The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid.	got7fsn_ti					See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'.							RESID:AA0044		biological_process											owl:Class	
GO:1905604	biolink:NamedThing	negative regulation of blood-brain barrier permeability	Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.	got7fsn_ti	downregulation of BBB permeability|down-regulation of blood/brain barrier permeability|downregulation of blood/brain barrier permeability|downregulation of blood-brain barrier permeability|down-regulation of blood-brain barrier permeability|inhibition of maintenance of permeability of blood-brain barrier|inhibition of maintenance of permeability of BBB|down-regulation of BBB permeability|negative regulation of blood/brain barrier permeability|negative regulation of BBB permeability						als	2016-10-26T13:18:25Z						biological_process											owl:Class	
GO:0070331	biolink:NamedThing	CD20-Lck-Fyn complex	A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn.	got7fsn_ti														cellular_component											owl:Class	
GO:0005759	biolink:NamedThing	mitochondrial matrix	The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.	got7fsn_ti	mitochondrial stroma|mitochondrial lumen										GO:0031980	Wikipedia:Mitochondrial_matrix|NIF_Subcellular:sao1804523077		cellular_component											owl:Class	
GO:0046314	biolink:NamedThing	phosphocreatine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.	got7fsn_ti	phosphocreatine anabolism|phosphocreatine synthesis|phosphocreatine formation|phosphocreatine biosynthesis													biological_process											owl:Class	
GO:0006603	biolink:NamedThing	phosphocreatine metabolic process	The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle.	got7fsn_ti	phosphocreatine metabolism													biological_process											owl:Class	
GO:0003975	biolink:NamedThing	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.	got7fsn_ti	chitobiosylpyrophosphoryldolichol synthase activity|UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase activity|uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase activity|UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase activity|UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase activity|UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase activity|N-acetylglucosamine-1-phosphate transferase activity|UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity|UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase activity|GlcNAc-1-P transferase activity|dolichol phosphate N-acetylglucosamine-1-phosphotransferase activity											Reactome:R-HSA-446191|EC:2.7.8.15|RHEA:13289|MetaCyc:2.7.8.15-RXN|Reactome:R-HSA-4549334		molecular_function											owl:Class	
GO:0047622	biolink:NamedThing	adenosine nucleosidase activity	Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.	got7fsn_ti	adenosine hydrolase activity|N-ribosyladenine ribohydrolase activity|adenosine ribohydrolase activity|adenosinase activity|ANase activity											MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN|RHEA:18669|EC:3.2.2.7		molecular_function											owl:Class	
GO:0008477	biolink:NamedThing	purine nucleosidase activity	Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.	got7fsn_ti	N-ribosyl purine ribohydrolase activity|N-D-ribosylpurine ribohydrolase activity|purine nucleoside hydrolase activity|purine ribonucleosidase activity|purine beta-ribosidase activity|ribonucleoside hydrolase activity|IAG-NH activity|IAG-nucleoside hydrolase activity|purine-specific nucleoside N-ribohydrolase activity|nucleosidase activity|purine-nucleoside ribohydrolase activity|nucleoside hydrolase activity|nucleosidase g activity|purine nucleosidase reaction|inosine-adenosine-guanosine preferring nucleoside hydrolase activity											RHEA:23344|MetaCyc:PURINE-NUCLEOSIDASE-RXN|EC:3.2.2.1		molecular_function											owl:Class	
GO:0061740	biolink:NamedThing	protein targeting to lysosome involved in chaperone-mediated autophagy	The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor.	got7fsn_ti							dph	2015-10-21T08:41:29Z						biological_process											owl:Class	
GO:0006622	biolink:NamedThing	protein targeting to lysosome	The process of directing proteins towards the lysosome using signals contained within the protein.	got7fsn_ti	protein-lysosome targeting													biological_process											owl:Class	
GO:0045435	biolink:NamedThing	lycopene epsilon cyclase activity	Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene).	got7fsn_ti	lycopene cyclase													molecular_function											owl:Class	
GO:0033276	biolink:NamedThing	transcription factor TFTC complex	A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0070461	biolink:NamedThing	SAGA-type complex	A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs).	got7fsn_ti	SAGA family complex													cellular_component											owl:Class	
GO:0055117	biolink:NamedThing	regulation of cardiac muscle contraction	Any process that modulates the frequency, rate or extent of cardiac muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0006942	biolink:NamedThing	regulation of striated muscle contraction	Any process that modulates the frequency, rate or extent of striated muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0033881	biolink:NamedThing	bile-acid-CoA hydrolase activity	Catalysis of the reaction: deoxycholoyl-CoA + H(2)O = CoA + deoxycholate + H(+).	got7fsn_ti	bile acid-coenzyme A hydrolase activity|deoxycholoyl-CoA hydrolase activity											KEGG_REACTION:R07295|RHEA:17693|EC:3.1.2.26|MetaCyc:BACOAHYDRO-RXN		molecular_function											owl:Class	
GO:0031044	biolink:NamedThing	O-glycan processing, core 8	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc.	got7fsn_ti														biological_process											owl:Class	
GO:0010622	biolink:NamedThing	specification of ovule identity	The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0005706	biolink:NamedThing	polytene chromosome ectopic fiber	A thread-like connection joining two regions of ectopically paired polytene chromosomes.	got7fsn_ti	polytene chromosome ectopic fibre													cellular_component											owl:Class	
GO:0097601	biolink:NamedThing	retina blood vessel maintenance	A retina homeostatic process preventing the degeneration of a retina blood vessel.	got7fsn_ti	maintenance of retina blood vessel|maintenance of retinal blood vessel|maintenance of choriocapillaris						pr	2014-05-11T18:42:24Z						biological_process											owl:Class	
GO:0061079	biolink:NamedThing	left horn of sinus venosus development	The progression of the left horn of the sinus venosus from its initial formation to the mature structure.	got7fsn_ti							dph	2010-04-08T02:40:27Z						biological_process											owl:Class	
GO:0097102	biolink:NamedThing	endothelial tip cell fate specification	The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.	got7fsn_ti	angiogenic tip cell fate specification						pr	2011-07-27T10:29:00Z						biological_process											owl:Class	
GO:0097101	biolink:NamedThing	blood vessel endothelial cell fate specification	The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.	got7fsn_ti							pr	2011-07-27T10:24:32Z						biological_process											owl:Class	
GO:0050221	biolink:NamedThing	prostaglandin-E2 9-reductase activity	Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.	got7fsn_ti	PGE2 9-ketoreductase activity|9-ketoprostaglandin reductase activity|PGE-9-ketoreductase activity|PGE(2) 9-oxoreductase activity|PGE(2) 9-ketoreductase activity|prostaglandin E2-9-oxoreductase activity|reductase, 15-hydroxy-9-oxoprostaglandin|PGE2 9-oxoreductase activity|PGE2-9-ketoreductase activity|prostaglandin E 9-ketoreductase activity|9-keto-prostaglandin E2 reductase activity|PGE2-9-OR|9-keto-prostaglandin E(2) reductase activity|prostaglandin-E(2) 9-oxoreductase activity|prostaglandin-E2 9-oxoreductase activity|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity											EC:1.1.1.189|Reactome:R-HSA-2161651|MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN|RHEA:24508		molecular_function											owl:Class	
GO:0002456	biolink:NamedThing	T cell mediated immunity	Any process involved in the carrying out of an immune response by a T cell.	got7fsn_ti	cell-mediated immunity|cellular immune response|T-cell mediated immunity|T lymphocyte mediated immunity|T-lymphocyte mediated immunity													biological_process											owl:Class	
GO:0002455	biolink:NamedThing	humoral immune response mediated by circulating immunoglobulin	An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.	got7fsn_ti	humoral defence mechanism|humoral immune response mediated by circulating antibody|circulating antibody mediated immune response|circulating immunoglobulin mediated immune response													biological_process											owl:Class	
GO:0006959	biolink:NamedThing	humoral immune response	An immune response mediated through a body fluid.	got7fsn_ti												Wikipedia:Humoral_immunity		biological_process											owl:Class	
GO:0007376	biolink:NamedThing	cephalic furrow formation	Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome.	got7fsn_ti														biological_process											owl:Class	
GO:0033712	biolink:NamedThing	1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity	Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.	got7fsn_ti	AFR|1,5-anhydro-D-mannitol:NADP+ oxidoreductase activity											MetaCyc:1.1.1.292-RXN|RHEA:24208|EC:1.1.1.292|KEGG_REACTION:R08194		molecular_function											owl:Class	
GO:0010230	biolink:NamedThing	alternative respiration	Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa.	got7fsn_ti														biological_process											owl:Class	
GO:0016407	biolink:NamedThing	acetyltransferase activity	Catalysis of the transfer of an acetyl group to an acceptor molecule.	got7fsn_ti	acetylase activity											Reactome:R-HSA-73736|Reactome:R-HSA-6792712|Reactome:R-HSA-5660660|Reactome:R-HSA-5628871|Reactome:R-HSA-5682044|Reactome:R-HSA-6805638		molecular_function											owl:Class	
GO:0035474	biolink:NamedThing	selective angioblast sprouting	The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel.	got7fsn_ti							bf	2010-04-23T10:03:55Z						biological_process											owl:Class	
GO:0019554	biolink:NamedThing	glutamate catabolic process to oxaloacetate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate.	got7fsn_ti	glutamate breakdown to oxaloacetate|glutamate degradation to oxaloacetate													biological_process											owl:Class	
GO:0043650	biolink:NamedThing	dicarboxylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.	got7fsn_ti	dicarboxylic acid synthesis|dicarboxylate biosynthetic process|dicarboxylate biosynthesis|dicarboxylic acid biosynthesis|dicarboxylic acid formation|dicarboxylic acid anabolism													biological_process											owl:Class	
GO:0098932	biolink:NamedThing	disruption by virus of host cell wall peptidoglycan during virus entry	A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry.	got7fsn_ti	degradation of host cell wall peptidoglycan by virus|degradation of host peptidoglycans during virus entry|disassembly by virus of host cell wall peptidoglycan|catabolism of host cell wall peptidoglycan by virus											VZ:3940		biological_process											owl:Class	
GO:0019048	biolink:NamedThing	modulation by virus of host process	The process in which a virus effects a change in the structure or processes of its host organism.	got7fsn_ti	disruption by virus of host cell|modulation by virus of host morphology or physiology|viral interaction with host|modulation by virus of host anatomy or process|host-virus interaction|virus-host interaction|viral-host process|modulation by virus of host anatomical structure or process|virus-host process	https://github.com/geneontology/go-ontology/issues/18605|https://github.com/geneontology/go-ontology/issues/18719					jl	2012-08-01T13:41:00Z			GO:0044661|GO:0044792	VZ:886		biological_process											owl:Class	
GO:0019174	biolink:NamedThing	tetrahydrothiophene 1-oxide reductase activity	Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor.	got7fsn_ti												MetaCyc:THTOREDUCT-RXN		molecular_function											owl:Class	
GO:0050317	biolink:NamedThing	tagatose kinase activity	Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+).	got7fsn_ti	ATP:D-tagatose 6-phosphotransferase activity|D-tagatose 6-phosphate kinase activity|tagatose 6-phosphate kinase (phosphorylating)											RHEA:15513|MetaCyc:TAGATOSE-KINASE-RXN|EC:2.7.1.101|KEGG_REACTION:R02927		molecular_function											owl:Class	
GO:0002079	biolink:NamedThing	inner acrosomal membrane	The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.	got7fsn_ti					Note that this term is not a descendant of 'organelle inner membrane ; GO:0019866' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.									cellular_component											owl:Class	
GO:0098035	biolink:NamedThing	viral DNA genome packaging via site-specific sequence recognition	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase.	got7fsn_ti							bm	2012-07-20T11:36:49Z						biological_process											owl:Class	
GO:0019073	biolink:NamedThing	viral DNA genome packaging	The packing of viral DNA into a capsid.	got7fsn_ti														biological_process											owl:Class	
GO:0033418	biolink:NamedThing	CUC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CUC codon.	got7fsn_ti	leucine tRNA|CTC codon-amino acid adaptor activity				Note that in the standard genetic code, CTC codes for leucine.									molecular_function											owl:Class	
GO:0102672	biolink:NamedThing	fatty acid alpha-oxygenase activity	Catalysis of the reaction: O2 + a 2,3,4-saturated fatty acid <=> a 2(R)-hydroperoxy fatty acid.	got7fsn_ti												MetaCyc:RXN-4121		molecular_function											owl:Class	
GO:0033446	biolink:NamedThing	AGC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AGC codon.	got7fsn_ti	serine tRNA				Note that in the standard genetic code, AGC codes for serine.									molecular_function											owl:Class	
GO:0001126	biolink:NamedThing	bacterial-type RNA polymerase preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on a bacterial-type RNA polymerase promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription.	got7fsn_ti	bacterial-type RNA polymerase transcriptional preinitiation complex formation|bacterial-type RNA polymerase transcription PIC biosynthesis|bacterial-type RNA polymerase transcription PIC formation						krc	2010-12-06T03:54:45Z						biological_process											owl:Class	
GO:0070897	biolink:NamedThing	transcription preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription.	got7fsn_ti	DNA-templated transcriptional preinitiation complex assembly|transcription PIC formation|transcriptional preinitiation complex formation|transcription PIC biosynthesis|DNA-dependent transcriptional preinitiation complex assembly						mah	2009-09-01T04:33:47Z						biological_process											owl:Class	
GO:0004435	biolink:NamedThing	phosphatidylinositol phospholipase C activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).	got7fsn_ti	phosphoinositide phospholipase C activity|phosphatidylinositol-4,5-bisphosphate hydrolysis|1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity|1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity|triphosphoinositide phosphodiesterase activity|PI-PLC activity|monophosphatidylinositol phosphodiesterase activity|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity|phosphoinositidase C activity											KEGG_REACTION:R03435|Reactome:R-HSA-1855221|Reactome:R-HSA-1855177|MetaCyc:3.1.4.11-RXN|Reactome:R-HSA-622382|Reactome:R-HSA-5607735|Reactome:R-HSA-1855214|EC:3.1.4.11|Reactome:R-HSA-111879|Reactome:R-HSA-167686|RHEA:33179|Reactome:R-HSA-202407|Reactome:R-HSA-2730847|Reactome:R-HSA-9032478		molecular_function											owl:Class	
GO:0004629	biolink:NamedThing	phospholipase C activity	Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.	got7fsn_ti	lipophosphodiesterase C|phosphatidase C|lecithinase C activity										GO:0042298	Reactome:R-HSA-1112666|EC:3.1.4.3|Reactome:R-HSA-5362553|Reactome:R-HSA-114689|Reactome:R-HSA-399998|Reactome:R-HSA-398193|MetaCyc:PHOSPHOLIPASE-C-RXN|Reactome:R-HSA-114688		molecular_function											owl:Class	
GO:1900766	biolink:NamedThing	emericellin biosynthetic process	The chemical reactions and pathways resulting in the formation of emericellin.	got7fsn_ti	Variecoxanthone B formation|emericellin biosynthesis|Variecoxanthone B biosynthetic process|emericellin synthesis|Variecoxanthone B synthesis|Variecoxanthone B biosynthesis|emericellin formation|emericellin anabolism|Variecoxanthone B anabolism						di	2012-06-04T09:18:29Z						biological_process											owl:Class	
GO:0051681	biolink:NamedThing	6-alpha-maltosylglucose catabolic process	The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose.	got7fsn_ti	isopanose catabolism|isopanose catabolic process													biological_process											owl:Class	
GO:0033549	biolink:NamedThing	MAP kinase phosphatase activity	Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate.	got7fsn_ti	MAPK phosphatase activity													molecular_function											owl:Class	
GO:0043662	biolink:NamedThing	peribacteroid fluid	The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0033309	biolink:NamedThing	SBF transcription complex	A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi4p and the activator Swi6p, and is associated with additional proteins known as Whi5p and Msa1p.	got7fsn_ti	SBF complex													cellular_component											owl:Class	
GO:0050620	biolink:NamedThing	phycocyanobilin:ferredoxin oxidoreductase activity	Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.	got7fsn_ti	(3Z)-phycocyanobilin:ferredoxin oxidoreductase activity											EC:1.3.7.5|RHEA:15309|MetaCyc:1.3.7.5-RXN		molecular_function											owl:Class	
GO:0016636	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	got7fsn_ti	oxidoreductase activity, acting on the CH-CH group of donors, iron-sulphur protein as acceptor											EC:1.3.7.-		molecular_function											owl:Class	
GO:0097609	biolink:NamedThing	longitudinal flagellum	A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus.	got7fsn_ti	longitudinal cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent. In this case community usage refers to 'flagellum' rather than 'cilium', hence the primary term name, but the cilium parentage is deliberate.		pr	2014-06-09T11:21:10Z						cellular_component											owl:Class	
GO:0010071	biolink:NamedThing	root meristem specification	The specification of a meristem which will give rise to a primary or lateral root.	got7fsn_ti														biological_process											owl:Class	
GO:1990725	biolink:NamedThing	cord factor receptor activity	Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	trehalose 6,6'-dimycolate receptor activity|TMD receptor activity						hjd	2015-04-07T20:53:31Z				Wikipedia:Cord_factor		molecular_function											owl:Class	
GO:0001778	biolink:NamedThing	plasma membrane repair	The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.	got7fsn_ti														biological_process											owl:Class	
GO:0007009	biolink:NamedThing	plasma membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.	got7fsn_ti	plasma membrane organization and biogenesis|plasma membrane organisation													biological_process											owl:Class	
GO:0052788	biolink:NamedThing	d-4,5 unsaturated beta-glucuronyl hydrolase activity	Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue.	got7fsn_ti	unsaturated beta-glucuronyl hydrolase activity						ai	2011-10-04T12:59:37Z						molecular_function											owl:Class	
GO:0018142	biolink:NamedThing	protein-DNA covalent cross-linking	The formation of a covalent cross-link between DNA and a protein.	got7fsn_ti	DNA-protein covalent cross-linking													biological_process											owl:Class	
GO:0006626	biolink:NamedThing	protein targeting to mitochondrion	The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.	got7fsn_ti	protein-mitochondrial targeting|protein targeting to mitochondria|protein import into mitochondrion|mitochondrial translocation|mitochondrial protein import										GO:0043681			biological_process											owl:Class	
GO:0072655	biolink:NamedThing	establishment of protein localization to mitochondrion	The directed movement of a protein to the mitochondrion or a part of the mitochondrion.	got7fsn_ti	establishment of protein localization in mitochondrion|establishment of protein localisation to mitochondrion						mah	2011-02-14T02:28:54Z						biological_process											owl:Class	
GO:0034174	biolink:NamedThing	toll-like receptor 12 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 12.	got7fsn_ti	TLR12 signaling pathway|toll-like receptor 12 signalling pathway													biological_process											owl:Class	
GO:0033730	biolink:NamedThing	arogenate dehydrogenase (NADP+) activity	Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2.	got7fsn_ti	TyrAAT2|L-arogenate:NADP+ oxidoreductase (decarboxylating) activity|TyrAa|pretyrosine dehydrogenase activity|arogenic dehydrogenase activity|TyrAAT1											MetaCyc:1.3.1.78-RXN|EC:1.3.1.78|RHEA:15417		molecular_function											owl:Class	
GO:0033731	biolink:NamedThing	arogenate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2.	got7fsn_ti	pretyrosine dehydrogenase activity|arogenic dehydrogenase activity|L-arogenate:NAD(P)+ oxidoreductase (decarboxylating) activity											EC:1.3.1.79|MetaCyc:1.3.1.79-RXN		molecular_function											owl:Class	
GO:0090133	biolink:NamedThing	mesendoderm migration	The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm.	got7fsn_ti							tb	2009-12-07T03:22:08Z						biological_process											owl:Class	
GO:0090132	biolink:NamedThing	epithelium migration	The process in which the population of cells that make up an epithelium undergo directed movement.	got7fsn_ti							tb	2009-12-07T03:19:34Z						biological_process											owl:Class	
GO:0072012	biolink:NamedThing	glomerulus vasculature development	The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.	got7fsn_ti	glomerulus capillary development						mah	2010-01-25T02:05:04Z						biological_process											owl:Class	
GO:0102173	biolink:NamedThing	24-methylenecycloartanol 4alpha-methyl oxidase activity	Catalysis of the reaction: 24-methylenecycloartanol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O.	got7fsn_ti												RHEA:58836|MetaCyc:RXN-11926		molecular_function											owl:Class	
GO:0019983	biolink:NamedThing	interleukin-9 binding	Binding to interleukin-9.	got7fsn_ti	IL-9 binding													molecular_function											owl:Class	
GO:0019590	biolink:NamedThing	L-arabitol catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.	got7fsn_ti	L-arabitol and xylitol degradation|L-arabitol degradation to xylulose 5-phosphate|L-arabitol breakdown to xylulose 5-phosphate|L-arabitol utilization											MetaCyc:LARABITOLUTIL-PWY		biological_process											owl:Class	
GO:0102916	biolink:NamedThing	sesamin synthase activity	Catalysis of the reaction: H+ + (+)-piperitol + NADPH + O2 <=> (+)-sesamin + NADP + 2 H2O.	got7fsn_ti												MetaCyc:RXN-8696|EC:1.14.19.74		molecular_function											owl:Class	
GO:0050123	biolink:NamedThing	N-acylmannosamine 1-dehydrogenase activity	Catalysis of the reaction: N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + H(+) + NADH.	got7fsn_ti	N-acetyl-D-mannosamine dehydrogenase activity|N-acyl-D-mannosamine:NAD+ 1-oxidoreductase activity|N-acyl-D-mannosamine dehydrogenase activity|N-acylmannosamine dehydrogenase activity											KEGG_REACTION:R02651|RHEA:11540|MetaCyc:N-ACYLMANNOSAMINE-1-DEHYDROGENASE-RXN|EC:1.1.1.233		molecular_function											owl:Class	
GO:0018120	biolink:NamedThing	peptidyl-arginine ADP-ribosylation	The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine.	got7fsn_ti												RESID:AA0168		biological_process											owl:Class	
GO:0018800	biolink:NamedThing	5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity	Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2.	got7fsn_ti	HpaG-2|HpaG2|5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase activity|5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)|OPET decarboxylase activity|5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase activity|5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase activity											RHEA:14397|MetaCyc:4.1.1.68-RXN|UM-BBD_reactionID:r0367|EC:4.1.1.68		molecular_function											owl:Class	
GO:0097393	biolink:NamedThing	telomeric repeat-containing RNA transcription	The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome.	got7fsn_ti	TERRA transcription						pr	2012-10-23T10:06:17Z						biological_process											owl:Class	
GO:0009112	biolink:NamedThing	nucleobase metabolic process	The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.	got7fsn_ti	nucleobase metabolism													biological_process											owl:Class	
GO:0061042	biolink:NamedThing	vascular wound healing	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.	got7fsn_ti							dph	2010-02-25T10:18:26Z						biological_process											owl:Class	
GO:0060055	biolink:NamedThing	angiogenesis involved in wound healing	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.	got7fsn_ti														biological_process											owl:Class	
GO:0046752	biolink:NamedThing	viral capsid precursor transport to host cell nucleus	Any process in which viral capsid precursors are transported to a specific location in the nucleus, thus accumulating the necessary components for assembly of a capsid.	got7fsn_ti	localization of viral capsid precursors in nucleus|viral capsid precursor localization to host cell nucleus|nuclear localization of viral capsid precursors|viral capsid precursor localisation in host cell nucleus|establishment and maintenance of viral capsid precursor localization in nucleus|viral capsid precursor localization in host cell nucleus													biological_process											owl:Class	
GO:0090635	biolink:NamedThing	extracellular core region of desmosome	The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner.	got7fsn_ti	desmoglea						tb	2015-04-20T16:10:51Z						cellular_component											owl:Class	
GO:1901164	biolink:NamedThing	negative regulation of trophoblast cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.	got7fsn_ti	inhibition of trophoblast cell migration|down-regulation of trophoblast cell migration|downregulation of trophoblast cell migration|down regulation of trophoblast cell migration						vk	2012-07-19T07:53:28Z						biological_process											owl:Class	
GO:0002344	biolink:NamedThing	B cell affinity maturation	The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.	got7fsn_ti	B-cell affinity maturation|B lymphocyte affinity maturation|B-lymphocyte affinity maturation													biological_process											owl:Class	
GO:0002343	biolink:NamedThing	peripheral B cell selection	Any B cell selection process that occurs in the periphery.	got7fsn_ti	peripheral B lymphocyte selection|peripheral B-cell selection|peripheral B-lymphocyte selection													biological_process											owl:Class	
GO:0071748	biolink:NamedThing	monomeric IgA immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	monomeric IgA2 antibody|monomeric IgA antibody|monomeric IgA1 antibody				Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0071746	biolink:NamedThing	IgA immunoglobulin complex, circulating	A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	IgA1 antibody|IgA2 antibody|IgA antibody				Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0046191	biolink:NamedThing	aerobic phenol-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.	got7fsn_ti	aerobic phenol-containing compound catabolism|aerobic phenol-containing compound breakdown|aerobic phenol-containing compound degradation													biological_process											owl:Class	
GO:0019336	biolink:NamedThing	phenol-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.	got7fsn_ti	phenol-containing compound catabolism|phenol-containing compound degradation|phenol-containing compound breakdown											MetaCyc:PHENOLDEG-PWY		biological_process											owl:Class	
GO:0102149	biolink:NamedThing	farnesylcysteine lyase activity	Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine  + O2 + H2O <=> (2-trans,6-trans)-farnesal + L-cysteine  + hydrogen peroxide.	got7fsn_ti												EC:1.8.3.6|RHEA:30231|MetaCyc:RXN-11623		molecular_function											owl:Class	
GO:0016670	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen.	got7fsn_ti	oxidoreductase activity, acting on sulphur group of donors, oxygen as acceptor											EC:1.8.3.-		molecular_function											owl:Class	
GO:0017189	biolink:NamedThing	N-terminal peptidyl-alanine acetylation	The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase.	got7fsn_ti					See also the molecular function terms 'peptide alpha-N-acetyltransferase activity ; GO:0004596' and 'ribosomal-protein-alanine N-acetyltransferase activity ; GO:0008999'.							RESID:AA0041		biological_process											owl:Class	
GO:0032250	biolink:NamedThing	negative regulation of adenosine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	inhibition of adenosine transport|downregulation of adenosine transport|down-regulation of adenosine transport|down regulation of adenosine transport													biological_process											owl:Class	
GO:0032247	biolink:NamedThing	negative regulation of purine nucleoside transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	downregulation of purine nucleoside transport|down regulation of purine nucleoside transport|down-regulation of purine nucleoside transport|inhibition of purine nucleoside transport													biological_process											owl:Class	
GO:0019136	biolink:NamedThing	deoxynucleoside kinase activity	Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.	got7fsn_ti	multifunctional deoxynucleoside kinase activity|multispecific deoxynucleoside kinase activity|ms-dNK|multisubstrate deoxyribonucleoside kinase activity|D. melanogaster deoxynucleoside kinase activity|ATP:deoxynucleoside 5'-phosphotransferase activity|Dm-dNK|Ms-dNK activity											MetaCyc:2.7.1.145-RXN|RHEA:12140|EC:2.7.1.145		molecular_function											owl:Class	
GO:0030007	biolink:NamedThing	cellular potassium ion homeostasis	Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.	got7fsn_ti											GO:0017079			biological_process											owl:Class	
GO:0055075	biolink:NamedThing	potassium ion homeostasis	Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0034236	biolink:NamedThing	protein kinase A catalytic subunit binding	Binding to one or both of the catalytic subunits of protein kinase A.	got7fsn_ti	PKA catalytic subunit binding													molecular_function											owl:Class	
GO:0051018	biolink:NamedThing	protein kinase A binding	Binding to a protein kinase A.	got7fsn_ti	PKA binding|protein kinase A anchoring activity				Note that this term is a direct child of 'protein binding ; GO:0005515' because it encompasses binding to either the catalytic or regulatory subunit of protein kinase A, and the latter does not have kinase activity.									molecular_function											owl:Class	
GO:0046289	biolink:NamedThing	isoflavonoid phytoalexin metabolic process	The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.	got7fsn_ti	isoflavonoid phytoalexin metabolism													biological_process											owl:Class	
GO:0046287	biolink:NamedThing	isoflavonoid metabolic process	The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.	got7fsn_ti	isoflavonoid metabolism													biological_process											owl:Class	
GO:0010056	biolink:NamedThing	atrichoblast fate specification	The process involved in the specification of an atrichoblast.	got7fsn_ti														biological_process											owl:Class	
GO:0030624	biolink:NamedThing	U6atac snRNA binding	Binding to a U6atac small nuclear RNA (U6atac snRNA).	got7fsn_ti														molecular_function											owl:Class	
GO:0004453	biolink:NamedThing	juvenile-hormone esterase activity	Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone.	got7fsn_ti	JH esterase activity|juvenile hormone analog esterase activity|JH-esterase activity|juvenile hormone carboxyesterase activity|methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase activity											EC:3.1.1.59|RHEA:16393|MetaCyc:JUVENILE-HORMONE-ESTERASE-RXN		molecular_function											owl:Class	
GO:1903231	biolink:NamedThing	mRNA binding involved in posttranscriptional gene silencing	Any mRNA binding that is involved in posttranscriptional gene silencing.	got7fsn_ti	mRNA binding involved in post-transcriptional gene silencing|mRNA binding involved in PTGS|mRNA binding involved in quelling|mRNA binding involved in cosuppression						jl	2014-07-31T10:30:43Z						molecular_function											owl:Class	
GO:0150100	biolink:NamedThing	RNA binding involved in posttranscriptional gene silencing	Any RNA binding that is involved in posttranscriptional gene silencing.	got7fsn_ti	RNA binding involved in cosuppression|RNA binding involved in PTGS|RNA binding involved in quelling|RNA binding involved in post-transcriptional gene silencing						bc	2019-03-11T11:48:27Z						molecular_function											owl:Class	
GO:0070388	biolink:NamedThing	procollagen-proline 4-dioxygenase complex, alpha(III) type	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform.	got7fsn_ti	prolyl 4-hydroxylase complex (alpha(III)-type)|procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(III) type													cellular_component											owl:Class	
GO:0016222	biolink:NamedThing	procollagen-proline 4-dioxygenase complex	A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.	got7fsn_ti	procollagen-proline, 2-oxoglutarate-4-dioxygenase complex|prolyl 4-hydroxylase complex													cellular_component											owl:Class	
GO:0008759	biolink:NamedThing	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine.	got7fsn_ti												EC:3.5.1.108		molecular_function											owl:Class	
GO:0034995	biolink:NamedThing	SC5b-7 complex	A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly.	got7fsn_ti														cellular_component											owl:Class	
GO:0072202	biolink:NamedThing	cell differentiation involved in metanephros development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-03-18T10:40:14Z						biological_process											owl:Class	
GO:0051469	biolink:NamedThing	vesicle fusion with vacuole	The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.	got7fsn_ti	heterotypic vacuole fusion (non-autophagic)|heterotypic vacuole fusion, non-autophagic										GO:0042146			biological_process											owl:Class	
GO:0006906	biolink:NamedThing	vesicle fusion	Fusion of the membrane of a transport vesicle with its target membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0033886	biolink:NamedThing	cellulose-polysulfatase activity	Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin.	got7fsn_ti	cellulose-sulfate sulfohydrolase activity											MetaCyc:3.1.6.7-RXN|EC:3.1.6.7		molecular_function											owl:Class	
GO:0032159	biolink:NamedThing	septin cap	A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.	got7fsn_ti														cellular_component											owl:Class	
GO:0052053	biolink:NamedThing	negative regulation by symbiont of host catalytic activity	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition of host enzyme activity|down-regulation by symbiont of host enzyme activity|downregulation by symbiont of host enzyme activity|down regulation by symbiont of host enzyme activity|negative regulation by symbiont of host enzyme activity|inhibition by symbiont of host enzyme activity|negative regulation by symbiont of host molecular function										GO:0052056			biological_process											owl:Class	
GO:0021629	biolink:NamedThing	olfactory nerve structural organization	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	got7fsn_ti	CN I structural organization|olfactory nerve structural organisation													biological_process											owl:Class	
GO:0043714	biolink:NamedThing	(R)-citramalate synthase activity	Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA.	got7fsn_ti	citramalate synthase											MetaCyc:RXN-7743|EC:2.3.1.182|RHEA:19045		molecular_function											owl:Class	
GO:0004506	biolink:NamedThing	squalene monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+).	got7fsn_ti	squalene oxydocyclase activity|squalene-2,3-epoxidase activity|squalene-2,3-epoxide cyclase activity|squalene hydroxylase activity|squalene 2,3-oxidocyclase activity|squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity|squalene epoxidase activity											RHEA:25282|MetaCyc:SQUALENE-MONOOXYGENASE-RXN|Reactome:R-HSA-191299|KEGG_REACTION:R02874|EC:1.14.14.17		molecular_function											owl:Class	
GO:0007430	biolink:NamedThing	terminal branching, open tracheal system	Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.	got7fsn_ti	terminal branching of trachea, cytoplasmic projection extension													biological_process											owl:Class	
GO:0097179	biolink:NamedThing	protease inhibitor complex	A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity.	got7fsn_ti	peptidase inhibitor complex						pr	2011-10-16T08:53:44Z						cellular_component											owl:Class	
GO:0033557	biolink:NamedThing	Slx1-Slx4 complex	A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.	got7fsn_ti														cellular_component											owl:Class	
GO:0038202	biolink:NamedThing	TORC1 signaling	A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.	got7fsn_ti	TORC1 signal transduction						bf	2013-12-09T14:43:29Z						biological_process											owl:Class	
GO:0050931	biolink:NamedThing	pigment cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.	got7fsn_ti	chromatophore differentiation|pigmented cell differentiation				Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore.						GO:0043358|GO:0043357			biological_process											owl:Class	
GO:0001880	biolink:NamedThing	Mullerian duct regression	The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.	got7fsn_ti														biological_process											owl:Class	
GO:0060033	biolink:NamedThing	anatomical structure regression	The developmental process in which an anatomical stucture is destroyed as a part of its normal progression.	got7fsn_ti	histolysis|tissue death													biological_process											owl:Class	
GO:0002062	biolink:NamedThing	chondrocyte differentiation	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti														biological_process											owl:Class	
GO:0006303	biolink:NamedThing	double-strand break repair via nonhomologous end joining	The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.	got7fsn_ti	NHEJ													biological_process											owl:Class	
GO:0006302	biolink:NamedThing	double-strand break repair	The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.	got7fsn_ti					Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable (PMID:22214610). To annotate gene products involved in mitochondrial double-strand break repair, please use GO:0097551 'mitochondrial double-strand break repair'.									biological_process											owl:Class	
GO:0002202	biolink:NamedThing	somatic diversification of variable lymphocyte receptors of jawless fish	The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish.	got7fsn_ti					Note that jawless fish refers to both lampreys (Petremyzontidae, ncbi_taxonomy_id:7746) and hagfish (Myxinidae, ncbi_taxonomy_id:7762).									biological_process											owl:Class	
GO:0097221	biolink:NamedThing	M/G1 phase-specific MADS box-forkhead transcription factor complex	A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2.	got7fsn_ti	PBF transcription complex|pombe cell cycle box binding factor complex|PBF complex|PCB binding factor complex						pr	2012-01-18T08:18:27Z						cellular_component											owl:Class	
GO:0018228	biolink:NamedThing	peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.	got7fsn_ti	peptidyl-S-geranylgeranyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-geranylgeranyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-geranylgeranyl-L-cysteine anabolism from peptidyl-cysteine											RESID:AA0104		biological_process											owl:Class	
GO:0055082	biolink:NamedThing	cellular chemical homeostasis	Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell.	got7fsn_ti														biological_process											owl:Class	
GO:0102451	biolink:NamedThing	kaempferide 3-O-methyltransferase activity	Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine  <=> 3,4'-dimethylkaempferol + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13937		molecular_function											owl:Class	
GO:1990399	biolink:NamedThing	epithelium regeneration	The regrowth of lost or destroyed epithelium.	got7fsn_ti	regeneration of epithelium						sl	2014-06-12T17:14:42Z						biological_process											owl:Class	
GO:0060489	biolink:NamedThing	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	The process in which a lung bud bifurcates parallel to the plane of the previous bud.	got7fsn_ti														biological_process											owl:Class	
GO:0060448	biolink:NamedThing	dichotomous subdivision of terminal units involved in lung branching	The process in which a lung bud bifurcates.	got7fsn_ti	bud bifurcation involved in lung branching													biological_process											owl:Class	
GO:0048562	biolink:NamedThing	embryonic organ morphogenesis	Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti														biological_process											owl:Class	
GO:0008725	biolink:NamedThing	DNA-3-methyladenine glycosylase activity	Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.	got7fsn_ti	DNA glycosidase I activity|3-methyladenine DNA glycosylase I|DNA-3-methyladenine glycosylase I activity|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|deoxyribonucleate 3-methyladenine glycosidase I|DNA-3-methyladenine glycosidase I activity											MetaCyc:3.2.2.21-RXN|EC:3.2.2.21|EC:3.2.2.20|MetaCyc:3.2.2.20-RXN		molecular_function											owl:Class	
GO:0043733	biolink:NamedThing	DNA-3-methylbase glycosylase activity	Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site.	got7fsn_ti	Mag III|DNA-3-methyladenine glycosylase III|MagIII													molecular_function											owl:Class	
GO:0009853	biolink:NamedThing	photorespiration	A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria.	got7fsn_ti												MetaCyc:PWY-181|Wikipedia:Photorespiration		biological_process											owl:Class	
GO:0070659	biolink:NamedThing	inner ear sensory epithelium regeneration	The regrowth of lost or destroyed inner ear sensory epithelia.	got7fsn_ti							mah	2009-05-28T04:21:09Z						biological_process											owl:Class	
GO:0021529	biolink:NamedThing	spinal cord oligodendrocyte cell differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0034859	biolink:NamedThing	benzothiazole monooxygenase activity	Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole.	got7fsn_ti												UM-BBD_reactionID:r1292		molecular_function											owl:Class	
GO:0050185	biolink:NamedThing	phosphatidylinositol deacylase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H(2)O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H(+).	got7fsn_ti	1-phosphatidyl-D-myo-inositol 2-acylhydrolase activity|phosphatidylinositol phospholipase A2 activity											KEGG_REACTION:R03360|EC:3.1.1.52|MetaCyc:PHOSPHATIDYLINOSITOL-DEACYLASE-RXN|RHEA:18001		molecular_function											owl:Class	
GO:0052874	biolink:NamedThing	FMN reductase (NADH) activity	Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+.	got7fsn_ti	NADH2 dehydrogenase (FMN)|NADH2:FMN oxidoreductase activity|NADH dehydrogenase (FMN) activity|SsuE|flavin mononucleotide reductase activity|NADH(2):FMN oxidoreductase activity|NADH-dependent FMN reductase activity|FMNH2:NAD+ oxidoreductase activity|NADH:flavin oxidoreductase activity|NADH-FMN reductase activity|NADH:FMN oxidoreductase activity|flavine mononucleotide reductase activity|NADH(2) dehydrogenase (FMN) activity											EC:1.5.1.39|RHEA:21620|KEGG_REACTION:R05705		molecular_function											owl:Class	
GO:0098624	biolink:NamedThing	3'-phosphoadenylylselenate reductase activity	Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+.	got7fsn_ti	PAPSe reductase activity											Reactome:R-HSA-2408548		molecular_function											owl:Class	
GO:0032620	biolink:NamedThing	interleukin-17 production	The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CTLA-8 production|IL-17 production|Cytotoxic T-lymphocyte-associated antigen 8 production|interleukin-17 secretion|interleukin-17 biosynthetic process										GO:0072615|GO:0042235			biological_process											owl:Class	
GO:0120039	biolink:NamedThing	plasma membrane bounded cell projection morphogenesis	The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13298					krc	2017-04-28T23:39:37Z						biological_process											owl:Class	
GO:0048858	biolink:NamedThing	cell projection morphogenesis	The process in which the anatomical structures of a cell projection are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0060117	biolink:NamedThing	auditory receptor cell development	The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti	auditory hair cell development													biological_process											owl:Class	
GO:0060119	biolink:NamedThing	inner ear receptor cell development	The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti	inner ear hair cell development													biological_process											owl:Class	
GO:0048060	biolink:NamedThing	negative gravitaxis	The directed movement of a motile cell or organism away from the source of gravity.	got7fsn_ti	negative geotactic behaviour|negative gravitactic behaviour|negative taxis in response to gravity|negative geotactic behavior|negative gravitactic behavior|negative taxis in response to gravitytaxis in response to gravitational stimulus										GO:0048063			biological_process											owl:Class	
GO:0042332	biolink:NamedThing	gravitaxis	The directed movement of a motile cell or organism in response to gravity.	got7fsn_ti	geotactic behaviour|taxis in response to gravitational stimulus|gravitactic behaviour|geotaxis|geotactic behavior|taxis in response to gravity|gravitactic behavior										GO:0048062			biological_process											owl:Class	
GO:0102688	biolink:NamedThing	dihydrozeatin UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + 9-(alpha-D-glucosyl)dihydrozeatin + UDP.	got7fsn_ti												MetaCyc:RXN-4725		molecular_function											owl:Class	
GO:0044860	biolink:NamedThing	protein localization to plasma membrane raft	A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft.	got7fsn_ti							jl	2014-07-23T16:25:01Z						biological_process											owl:Class	
GO:1903044	biolink:NamedThing	protein localization to membrane raft	A process in which a protein is transported to, or maintained in, a location within a membrane raft.	got7fsn_ti	protein localisation to membrane raft|protein localization in membrane raft|protein localisation in membrane raft						dl	2014-05-21T10:49:03Z						biological_process											owl:Class	
GO:0033114	biolink:NamedThing	cyanelle thylakoid lumen	The volume enclosed by a cyanelle thylakoid membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0102180	biolink:NamedThing	4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity	Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O.	got7fsn_ti												RHEA:59036|MetaCyc:RXN-11936		molecular_function											owl:Class	
GO:0061060	biolink:NamedThing	negative regulation of peptidoglycan recognition protein signaling pathway	Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.	got7fsn_ti	negative regulation of peptidoglycan recognition protein signalling pathway						dph	2010-03-02T12:38:42Z						biological_process											owl:Class	
GO:0002832	biolink:NamedThing	negative regulation of response to biotic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.	got7fsn_ti	inhibition of response to biotic stimulus|down-regulation of response to biotic stimulus|downregulation of response to biotic stimulus|down regulation of response to biotic stimulus				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0060832	biolink:NamedThing	oocyte animal/vegetal axis specification	The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.	got7fsn_ti							dph	2009-08-11T03:11:06Z						biological_process											owl:Class	
GO:0009295	biolink:NamedThing	nucleoid	The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.	got7fsn_ti												Wikipedia:Nucleoid		cellular_component											owl:Class	
GO:0071705	biolink:NamedThing	nitrogen compound transport	The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							mah	2010-03-08T03:56:28Z						biological_process											owl:Class	
GO:0036410	biolink:NamedThing	Mst2 histone acetyltransferase complex	A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6.	got7fsn_ti	Mst2 complex|Mst2 histone H3K14 acetyltransferase complex|Mst2 H3K14 acetyltransferase complex						bf	2013-08-21T10:11:32Z						cellular_component											owl:Class	
GO:0047760	biolink:NamedThing	butyrate-CoA ligase activity	Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA.	got7fsn_ti	fatty acid activating enzyme|butanoate:CoA ligase (AMP-forming)|acyl-activating enzyme activity|butyryl-CoA synthetase activity|medium chain acyl-CoA synthetase activity|short-chain acyl-CoA synthetase activity|fatty acid thiokinase (medium chain) activity|butyryl-coenzyme A synthetase activity|fatty acyl coenzyme A synthetase activity|L-(+)-3-hydroxybutyryl CoA ligase activity											MetaCyc:BUTYRATE--COA-LIGASE-RXN|RHEA:24336|EC:6.2.1.2|Reactome:R-HSA-8875013		molecular_function											owl:Class	
GO:0007425	biolink:NamedThing	epithelial cell fate determination, open tracheal system	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster.	got7fsn_ti	tracheal epithelial cell fate determination|tracheal cell fate determination|tracheal placode cell fate determination										GO:0046846			biological_process											owl:Class	
GO:0043083	biolink:NamedThing	synaptic cleft	The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.	got7fsn_ti												NIF_Subcellular:sao243541954		cellular_component											owl:Class	
GO:0005576	biolink:NamedThing	extracellular region	The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.	got7fsn_ti	extracellular				Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.							Wikipedia:Extracellular		cellular_component											owl:Class	
GO:0052699	biolink:NamedThing	ergothioneine biosynthetic process	The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.	got7fsn_ti	ergothioneine biosynthesis|ergothioneine anabolism|2-mercaptoergothioneine trimethylbetaine biosynthetic process|ergothioneine formation|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate biosynthetic process|2-mercaptoergothioneine trimethylbetaine formation|2-mercaptoergothioneine trimethylbetaine anabolism|2-mercaptoergothioneine trimethylbetaine synthesis|2-mercaptoergothioneine trimethylbetaine biosynthesis|ergothioneine synthesis						ai	2011-08-01T03:56:19Z						biological_process											owl:Class	
GO:0052703	biolink:NamedThing	cellular modified histidine biosynthetic process	The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	got7fsn_ti	cellular histidine derivative anabolism|cellular modified histidine synthesis|histidine derivative biosynthetic process|cellular modified histidine anabolism|cellular histidine derivative biosynthetic process|cellular modified histidine biosynthesis|cellular histidine derivative biosynthesis|cellular histidine derivative formation|cellular modified histidine formation|cellular histidine derivative synthesis						ai	2011-08-01T03:49:39Z						biological_process											owl:Class	
GO:0055079	biolink:NamedThing	aluminum ion homeostasis	Any process involved in the maintenance of an internal steady state of aluminum ions within an organism or cell.	got7fsn_ti	aluminium ion homeostasis													biological_process											owl:Class	
GO:0044208	biolink:NamedThing	'de novo' AMP biosynthetic process	The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).	got7fsn_ti							jl	2009-10-22T02:48:30Z						biological_process											owl:Class	
GO:0006167	biolink:NamedThing	AMP biosynthetic process	The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.	got7fsn_ti	AMP formation|AMP anabolism|AMP synthesis|AMP biosynthesis													biological_process											owl:Class	
GO:0044352	biolink:NamedThing	pinosome	A membrane-bounded, uncoated intracellular vesicle formed by the process of pinocytosis.	got7fsn_ti	pinocytic vesicle						jl	2011-08-11T10:51:13Z				NIF_Subcellular:sao1925368674		cellular_component											owl:Class	
GO:0005768	biolink:NamedThing	endosome	A vacuole to which materials ingested by endocytosis are delivered.	got7fsn_ti												NIF_Subcellular:sao1720343330|Wikipedia:Endosome		cellular_component											owl:Class	
GO:0009047	biolink:NamedThing	dosage compensation by hyperactivation of X chromosome	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0007549	biolink:NamedThing	dosage compensation	Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes.	got7fsn_ti												Wikipedia:Dosage_compensation		biological_process											owl:Class	
GO:0048579	biolink:NamedThing	negative regulation of long-day photoperiodism, flowering	Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	got7fsn_ti	down regulation of long-day photoperiodism, flowering|inhibition of long-day photoperiodism, flowering|downregulation of long-day photoperiodism, flowering|down-regulation of long-day photoperiodism, flowering													biological_process											owl:Class	
GO:0060776	biolink:NamedThing	simple leaf morphogenesis	The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided.	got7fsn_ti							dph	2009-07-25T07:08:44Z						biological_process											owl:Class	
GO:0008310	biolink:NamedThing	single-stranded DNA 3'-5' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.	got7fsn_ti	ssDNA-specific 3'-5' exodeoxyribonuclease activity|single-stranded DNA specific 3'-5' exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0033161	biolink:NamedThing	mitogen-activated protein kinase kinase kinase kinase binding	Binding to a mitogen-activated protein kinase kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase kinase.	got7fsn_ti	MAPKKKK binding													molecular_function											owl:Class	
GO:0030377	biolink:NamedThing	urokinase plasminogen activator receptor activity	Combining with the urokinase plasminogen activator to initiate a change in cell activity.	got7fsn_ti	U-plasminogen activator receptor activity|urokinase plasminogen activator receptor|uPAR											Wikipedia:Urokinase_receptor		molecular_function											owl:Class	
GO:0002474	biolink:NamedThing	antigen processing and presentation of peptide antigen via MHC class I	The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.	got7fsn_ti	peptide antigen processing and presentation via MHC class I													biological_process											owl:Class	
GO:0019969	biolink:NamedThing	interleukin-10 binding	Binding to interleukin-10.	got7fsn_ti	IL-10 binding													molecular_function											owl:Class	
GO:0032891	biolink:NamedThing	negative regulation of organic acid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	downregulation of organic acid transport|down regulation of organic acid transport|inhibition of organic acid transport|down-regulation of organic acid transport													biological_process											owl:Class	
GO:0002776	biolink:NamedThing	antimicrobial peptide secretion	The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.	got7fsn_ti														biological_process											owl:Class	
GO:0061956	biolink:NamedThing	penetration of cumulus oophorus	The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.	got7fsn_ti	penetration of cumulus cells layer|penetration of cumulus mass						dph	2017-11-10T20:14:18Z						biological_process											owl:Class	
GO:1900797	biolink:NamedThing	cordyol C metabolic process	The chemical reactions and pathways involving cordyol C.	got7fsn_ti	cordyol C metabolism						di	2012-06-04T09:47:48Z						biological_process											owl:Class	
GO:0046364	biolink:NamedThing	monosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.	got7fsn_ti	monosaccharide formation|monosaccharide synthesis|monosaccharide biosynthesis|monosaccharide anabolism													biological_process											owl:Class	
GO:0060984	biolink:NamedThing	epicardium-derived cardiac vascular smooth muscle cell development	The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state.	got7fsn_ti							dph	2009-10-06T03:07:09Z						biological_process											owl:Class	
GO:0060948	biolink:NamedThing	cardiac vascular smooth muscle cell development	The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.	got7fsn_ti	heart vascular smooth muscle cell development						dph	2009-09-29T03:00:24Z						biological_process											owl:Class	
GO:0000007	biolink:NamedThing	low-affinity zinc ion transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti														molecular_function											owl:Class	
GO:0039504	biolink:NamedThing	suppression by virus of host adaptive immune response	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).	got7fsn_ti	inhibition of host adaptive immune response by virus|negative regulation by virus of host adaptive immunity|suppression by virus of host acquired immune response|negative regulation by virus of host adaptive immune response						bf	2011-05-11T04:41:54Z						biological_process											owl:Class	
GO:0002820	biolink:NamedThing	negative regulation of adaptive immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.	got7fsn_ti	inhibition of adaptive immune response|downregulation of adaptive immune response|down-regulation of adaptive immune response|down regulation of adaptive immune response													biological_process											owl:Class	
GO:0010362	biolink:NamedThing	negative regulation of anion channel activity by blue light	Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.	got7fsn_ti	negative regulation by blue light of anion channel activity|inhibition by blue light of anion channel activity													biological_process											owl:Class	
GO:0010360	biolink:NamedThing	negative regulation of anion channel activity	Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.	got7fsn_ti														biological_process											owl:Class	
GO:0052921	biolink:NamedThing	acetone-cyanohydrin acetone-lyase (cyanide-forming) activity	Catalysis of the reaction: acetone cyanohydrin = hydrogen cyanide + acetone.	got7fsn_ti												RHEA:11932|KEGG_REACTION:R01553|EC:4.1.2.46|MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN		molecular_function											owl:Class	
GO:0052919	biolink:NamedThing	aliphatic (R)-hydroxynitrile lyase activity	Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide.	got7fsn_ti	(R)-oxynitrilase activity|(R)-hydroxynitrile lyase activity|(R)-HNL activity											EC:4.1.2.46		molecular_function											owl:Class	
GO:0036131	biolink:NamedThing	prostaglandin D2 11-ketoreductase activity	Catalysis of the reaction: prostaglandin D2 + H+ + NADPH -> 11-epi-prostaglandin F2alpha + NADP+.	got7fsn_ti	prostaglandin 11-keto reductase|PGD2 11-ketoreductase						bf	2012-03-05T10:27:29Z				EC:1.1.1.188|RHEA:45316|KEGG_REACTION:R02799|Reactome:R-HSA-2161614		molecular_function											owl:Class	
GO:0034714	biolink:NamedThing	type III transforming growth factor beta receptor binding	Binding to a type III transforming growth factor beta receptor.	got7fsn_ti	TGF-beta type III binding|transforming growth factor beta ligand binding to type III receptor|type IIII TGF-beta binding|transforming growth factor beta receptor type III binding|betaglycan binding													molecular_function											owl:Class	
GO:0005160	biolink:NamedThing	transforming growth factor beta receptor binding	Binding to a transforming growth factor beta receptor.	got7fsn_ti	TGFbeta receptor binding|activin|TGF-beta receptor binding|transforming growth factor beta receptor ligand|inhibin|transforming growth factor beta|transforming growth factor beta receptor anchoring activity|transforming growth factor beta ligand binding to type II receptor|transforming growth factor beta ligand binding to type I receptor													molecular_function											owl:Class	
GO:0097361	biolink:NamedThing	CIA complex	The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.	got7fsn_ti	cytosolic iron-sulfur protein assembly complex						pr	2012-07-20T02:07:22Z						cellular_component											owl:Class	
GO:0048917	biolink:NamedThing	posterior lateral line ganglion development	The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.	got7fsn_ti	gPLL development													biological_process											owl:Class	
GO:0048336	biolink:NamedThing	positive regulation of mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination.	got7fsn_ti	stimulation of mesodermal cell fate determination|up regulation of mesodermal cell fate determination|up-regulation of mesodermal cell fate determination|activation of mesodermal cell fate determination|upregulation of mesodermal cell fate determination													biological_process											owl:Class	
GO:0045597	biolink:NamedThing	positive regulation of cell differentiation	Any process that activates or increases the frequency, rate or extent of cell differentiation.	got7fsn_ti	stimulation of cell differentiation|up regulation of cell differentiation|upregulation of cell differentiation|activation of cell differentiation|up-regulation of cell differentiation													biological_process											owl:Class	
GO:0120126	biolink:NamedThing	response to copper ion starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion.	got7fsn_ti							krc	2018-02-12T19:49:19Z						biological_process											owl:Class	
GO:0072426	biolink:NamedThing	response to G2 DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling.	got7fsn_ti	response to signal involved in G2/M transition DNA damage checkpoint|G2/M transition DNA damage checkpoint effector process						mah	2010-12-08T04:26:35Z						biological_process											owl:Class	
GO:0072423	biolink:NamedThing	response to DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling.	got7fsn_ti	response to signal involved in DNA damage checkpoint|DNA damage checkpoint effector process						mah	2010-12-08T04:20:25Z						biological_process											owl:Class	
GO:0002363	biolink:NamedThing	alpha-beta T cell lineage commitment	The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell.	got7fsn_ti	alpha-beta T-lymphocyte lineage commitment|alpha-beta T-cell lineage commitment|alpha-beta T lymphocyte lineage commitment													biological_process											owl:Class	
GO:0002360	biolink:NamedThing	T cell lineage commitment	The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.	got7fsn_ti	T-cell lineage commitment|T lymphocyte lineage commitment|T-lymphocyte lineage commitment													biological_process											owl:Class	
GO:0000418	biolink:NamedThing	RNA polymerase IV complex	RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex.	got7fsn_ti	DNA-directed RNA polymerase IV complex|DNA-directed RNA polymerase IVa complex										GO:0000420			cellular_component											owl:Class	
GO:0000378	biolink:NamedThing	RNA exon ligation	The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction.	got7fsn_ti					Note that this is not a part of spliceosomal RNA splicing.									biological_process											owl:Class	
GO:0016070	biolink:NamedThing	RNA metabolic process	The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.	got7fsn_ti	RNA metabolism													biological_process											owl:Class	
GO:1990671	biolink:NamedThing	vesicle fusion with Golgi medial cisterna membrane	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles.	got7fsn_ti							bhm	2015-03-02T11:31:01Z						biological_process											owl:Class	
GO:0048280	biolink:NamedThing	vesicle fusion with Golgi apparatus	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.	got7fsn_ti														biological_process											owl:Class	
GO:1990203	biolink:NamedThing	MdtBC Complex	A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane.	got7fsn_ti	multidrug efflux pump MdtBC						bhm	2013-10-04T21:22:18Z						cellular_component											owl:Class	
GO:1902495	biolink:NamedThing	transmembrane transporter complex	A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.	got7fsn_ti							bhm	2013-11-13T16:23:04Z						cellular_component											owl:Class	
GO:0102099	biolink:NamedThing	FAD-dependent urate hydroxylase activity	Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 <=> 5-hydroxyisouric acid + NAD + H2O.	got7fsn_ti												RHEA:27329|MetaCyc:RXN-11186|EC:1.14.13.113		molecular_function											owl:Class	
GO:0099514	biolink:NamedThing	synaptic vesicle cytoskeletal transport	The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors.	got7fsn_ti														biological_process											owl:Class	
GO:0030705	biolink:NamedThing	cytoskeleton-dependent intracellular transport	The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0033583	biolink:NamedThing	rhabdomere membrane	The portion of the plasma membrane surrounding the rhabdomere.	got7fsn_ti														cellular_component											owl:Class	
GO:0047628	biolink:NamedThing	ADP-thymidine kinase activity	Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate.	got7fsn_ti	adenosine diphosphate-thymidine phosphotransferase activity|ADP:dThd phosphotransferase activity|ADP:thymidine 5'-phosphotransferase activity											RHEA:13413|EC:2.7.1.118|MetaCyc:ADP--THYMIDINE-KINASE-RXN		molecular_function											owl:Class	
GO:0048904	biolink:NamedThing	anterior lateral line neuromast cupula development	The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.	got7fsn_ti														biological_process											owl:Class	
GO:0048887	biolink:NamedThing	cupula development	The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.	got7fsn_ti														biological_process											owl:Class	
GO:0009399	biolink:NamedThing	nitrogen fixation	The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.	got7fsn_ti												MetaCyc:N2FIX-PWY|Wikipedia:Nitrogen_fixation		biological_process											owl:Class	
GO:0072255	biolink:NamedThing	metanephric glomerular mesangial cell development	The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.	got7fsn_ti							mah	2010-03-19T04:06:58Z						biological_process											owl:Class	
GO:0052128	biolink:NamedThing	positive energy taxis	The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.	got7fsn_ti														biological_process											owl:Class	
GO:0006019	biolink:NamedThing	deoxyribose 5-phosphate phosphorylation	The process of introducing a phosphate group into deoxyribose 5-phosphate to produce deoxyribose bisphosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0046389	biolink:NamedThing	deoxyribose 5-phosphate metabolic process	The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose.	got7fsn_ti	deoxyribose 5-phosphate metabolism													biological_process											owl:Class	
GO:0044727	biolink:NamedThing	DNA demethylation of male pronucleus	The active DNA demethylation of the paternal genome that takes place before the first cell division.	got7fsn_ti							jl	2012-10-24T14:25:35Z						biological_process											owl:Class	
GO:0043045	biolink:NamedThing	DNA methylation involved in embryo development	The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression.	got7fsn_ti	de novo DNA methylation													biological_process											owl:Class	
GO:0051783	biolink:NamedThing	regulation of nuclear division	Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.	got7fsn_ti														biological_process											owl:Class	
GO:0001888	biolink:NamedThing	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.	got7fsn_ti	UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity|alpha-1,4-N-acetylglucosaminyltransferase activity|glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|alpha-N-acetylglucosaminyltransferase I activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity|alpha1,4-N-acetylglucosaminyltransferase activity											RHEA:16221|MetaCyc:2.4.1.223-RXN|EC:2.4.1.223		molecular_function											owl:Class	
GO:0102272	biolink:NamedThing	homophytochelatin synthase activity (polymer-forming)	Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine.	got7fsn_ti												MetaCyc:RXN-12528		molecular_function											owl:Class	
GO:0071223	biolink:NamedThing	cellular response to lipoteichoic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	got7fsn_ti	cellular response to LTA						mah	2009-12-03T01:31:00Z						biological_process											owl:Class	
GO:0061110	biolink:NamedThing	dense core granule biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule.	got7fsn_ti							dph	2010-05-01T09:40:11Z						biological_process											owl:Class	
GO:0044085	biolink:NamedThing	cellular component biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.	got7fsn_ti	cellular component biogenesis at cellular level										GO:0071843			biological_process											owl:Class	
GO:0019956	biolink:NamedThing	chemokine binding	Binding to a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.	got7fsn_ti														molecular_function											owl:Class	
GO:0007507	biolink:NamedThing	heart development	The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	got7fsn_ti	cardiac development|dorsal vessel development										GO:0007511	Wikipedia:Heart_development		biological_process											owl:Class	
GO:0002950	biolink:NamedThing	ceramide phosphoethanolamine synthase activity	Catalysis of the reaction: CDP-ethanolamine + a ceramide = CMP + a ceramide phosphoethanolamine.	got7fsn_ti							hjd	2016-08-16T13:41:21Z				Reactome:R-HSA-8959462		molecular_function											owl:Class	
GO:0070198	biolink:NamedThing	protein localization to chromosome, telomeric region	Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.	got7fsn_ti	protein localisation to chromosome, telomeric region|protein localization to telomere													biological_process											owl:Class	
GO:0042746	biolink:NamedThing	circadian sleep/wake cycle, wakefulness	The part of the circadian sleep/wake cycle where the organism is not asleep.	got7fsn_ti														biological_process											owl:Class	
GO:0022410	biolink:NamedThing	circadian sleep/wake cycle process	A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.	got7fsn_ti														biological_process											owl:Class	
GO:0048327	biolink:NamedThing	axial mesodermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	axial mesoderm cell fate specification													biological_process											owl:Class	
GO:0007501	biolink:NamedThing	mesodermal cell fate specification	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	mesoderm cell fate specification				Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'.									biological_process											owl:Class	
GO:0061968	biolink:NamedThing	maintenance of left/right asymmetry	The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.	got7fsn_ti							dph	2018-02-12T16:38:47Z						biological_process											owl:Class	
GO:0051678	biolink:NamedThing	pullulan catabolic process	The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.	got7fsn_ti														biological_process											owl:Class	
GO:0047246	biolink:NamedThing	luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity	Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP.	got7fsn_ti	uridine diphosphoglucuronate-luteolin 7-O-glucuronide glucuronosyltransferase activity|luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase activity|LMT activity|UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase activity|UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase activity											EC:2.4.1.190|KEGG_REACTION:R06827|MetaCyc:2.4.1.190-RXN|RHEA:14149		molecular_function											owl:Class	
GO:0015020	biolink:NamedThing	glucuronosyltransferase activity	Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.	got7fsn_ti	UDP-glucuronyltransferase activity|uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|phenyl-UDP-glucuronosyltransferase activity|UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|UDP glucuronyltransferase activity|1-naphthol glucuronyltransferase activity|3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|bilirubin UDPGT activity|UDP-glucuronosyltransferase activity|GT activity|uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|bilirubin uridine diphosphoglucuronyltransferase activity|p-nitrophenol UDP-glucuronosyltransferase activity|uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|PNP-UDPGT|ciramadol UDP-glucuronyltransferase activity|bilirubin UDP-glucuronosyltransferase activity|uridine diphosphate glucuronyltransferase activity|4-nitrophenol UDP-glucuronyltransferase activity|uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|UDP glucuronic acid transferase activity|17-OH steroid UDPGT activity|p-hydroxybiphenyl UDP glucuronyltransferase activity|3-OH androgenic UDPGT activity|uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|4-methylumbelliferone UDP-glucuronosyltransferase activity|UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|UDP glucuronate-estriol glucuronosyltransferase activity|17beta-hydroxysteroid UDP-glucuronosyltransferase activity|1-naphthol-UDP-glucuronosyltransferase activity|3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|4-nitrophenol UDPGT activity|p-nitrophenol UDP-glucuronyltransferase activity|4-hydroxybiphenyl UDP-glucuronosyltransferase activity|UDP glucuronate-estradiol-glucuronosyltransferase activity|UDPGT activity|UDP-glucuronate-bilirubin glucuronyltransferase activity|uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|bilirubin monoglucuronide glucuronyltransferase activity|UDPGA-glucuronyltransferase activity|p-phenylphenol glucuronyltransferase activity|estriol UDPglucuronosyltransferase activity|estrone UDPglucuronosyltransferase activity|morphine glucuronyltransferase activity|bilirubin glucuronyltransferase activity|pnp-UDPGT activity|p-nitrophenylglucuronosyltransferase activity|uridine 5'-diphosphoglucuronyltransferase activity|UDPGA transferase activity|uridine diphosphoglucuronyltransferase activity|uridine diphosphoglucuronosyltransferase activity|UDP glucuronosyltransferase activity										GO:0003981	Reactome:R-HSA-9036102|Reactome:R-HSA-159179|RHEA:21032|Reactome:R-HSA-5604954|Reactome:R-HSA-5604975|Reactome:R-HSA-159194|Reactome:R-HSA-9036104|Reactome:R-HSA-5617143|MetaCyc:UDP-GLUCURONOSYLTRANSFERASE-RXN|Reactome:R-HSA-174931|Reactome:R-HSA-9638097|Reactome:R-HSA-174916|Reactome:R-HSA-2162099|Reactome:R-HSA-9632038|Reactome:R-HSA-8941701|Reactome:R-HSA-9632039|EC:2.4.1.17		molecular_function											owl:Class	
GO:0070167	biolink:NamedThing	regulation of biomineral tissue development	Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.	got7fsn_ti														biological_process											owl:Class	
GO:0060349	biolink:NamedThing	bone morphogenesis	The process in which bones are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0004160	biolink:NamedThing	dihydroxy-acid dehydratase activity	Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.	got7fsn_ti	dihydroxy acid dehydrase activity|DHAD|alpha,beta-dihydroxyisovalerate dehydratase activity|2,3-dihydroxyisovalerate dehydratase activity|acetohydroxyacid dehydratase activity|alpha,beta-dihydroxyacid dehydratase activity|2,3-dihydroxy-acid hydro-lyase activity|2,3-dihydroxy-acid hydro-lyase (3-methyl-2-oxobutanoate-forming)											MetaCyc:DIHYDROXYISOVALDEHYDRAT-RXN|EC:4.2.1.9|RHEA:20936		molecular_function											owl:Class	
GO:0030832	biolink:NamedThing	regulation of actin filament length	Any process that controls the length of actin filaments in a cell.	got7fsn_ti					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:0032956	biolink:NamedThing	regulation of actin cytoskeleton organization	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.	got7fsn_ti	regulation of actin cytoskeleton organisation|regulation of actin cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:0009081	biolink:NamedThing	branched-chain amino acid metabolic process	The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.	got7fsn_ti	branched chain family amino acid metabolism													biological_process											owl:Class	
GO:0018147	biolink:NamedThing	molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)	The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide).	got7fsn_ti												RESID:AA0248		biological_process											owl:Class	
GO:0050844	biolink:NamedThing	peptidyl-selenocysteine modification	The modification of peptidyl-selenocysteine.	got7fsn_ti														biological_process											owl:Class	
GO:0018938	biolink:NamedThing	2-nitropropane metabolic process	The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol.	got7fsn_ti	2-nitropropane metabolism											MetaCyc:PWY-723|UM-BBD_pathwayID:npp		biological_process											owl:Class	
GO:0044684	biolink:NamedThing	dihydromethanopterin reductase activity	Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP.	got7fsn_ti							jl	2012-08-15T13:57:55Z				RHEA:42804|EC:1.5.99.15		molecular_function											owl:Class	
GO:0043808	biolink:NamedThing	lyso-ornithine lipid acyltransferase activity	Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein].	got7fsn_ti														molecular_function											owl:Class	
GO:0001640	biolink:NamedThing	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.	got7fsn_ti	adenylyl cyclase inhibiting metabotropic glutamate receptor activity|adenylate cyclase inhibiting metabotropic glutamate receptor activity													molecular_function											owl:Class	
GO:0008066	biolink:NamedThing	glutamate receptor activity	Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0018077	biolink:NamedThing	protein iodination	The addition of one or more iodine atoms to an amino acid residue in a protein.	got7fsn_ti	protein amino acid iodination													biological_process											owl:Class	
GO:0004793	biolink:NamedThing	threonine aldolase activity	Catalysis of the reaction: L-threonine = glycine + acetaldehyde.	got7fsn_ti	L-threonine acetaldehyde-lyase (glycine-forming)|L-threonine acetaldehyde-lyase activity|L-threonine aldolase activity											EC:4.1.2.5|MetaCyc:THREONINE-ALDOLASE-RXN|RHEA:19625		molecular_function											owl:Class	
GO:0006304	biolink:NamedThing	DNA modification	The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.	got7fsn_ti														biological_process											owl:Class	
GO:0080004	biolink:NamedThing	thalian-diol desaturase activity	Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15.	got7fsn_ti												EC:1.14.21.-|MetaCyc:RXN-9637		molecular_function											owl:Class	
GO:0009022	biolink:NamedThing	tRNA nucleotidyltransferase activity	Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.	got7fsn_ti	RNase PH activity|tRNA:phosphate nucleotidyltransferase activity|phosphate-dependent exonuclease activity|ribonuclease PH activity				Note that, although the enzyme to which this term refers is also known as 'ribonuclease PH', and degrades tRNA in the 3'-5' direction in vivo, the term does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.							MetaCyc:TRNA-NUCLEOTIDYLTRANSFERASE-RXN|RHEA:10628|EC:2.7.7.56		molecular_function											owl:Class	
GO:0030334	biolink:NamedThing	regulation of cell migration	Any process that modulates the frequency, rate or extent of cell migration.	got7fsn_ti														biological_process											owl:Class	
GO:0046199	biolink:NamedThing	cresol catabolic process	The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.	got7fsn_ti	cresol degradation|cresol breakdown|cresol catabolism													biological_process											owl:Class	
GO:0102780	biolink:NamedThing	sitosterol hydroxylase activity	Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-7876		molecular_function											owl:Class	
GO:0008797	biolink:NamedThing	aspartate ammonia-lyase activity	Catalysis of the reaction: L-aspartate = fumarate + NH3.	got7fsn_ti	L-aspartase activity|L-aspartate ammonia-lyase activity|aspartase activity|L-aspartate ammonia-lyase (fumarate-forming)|fumaric aminase activity											RHEA:16601|EC:4.3.1.1|MetaCyc:ASPARTASE-RXN		molecular_function											owl:Class	
GO:0019834	biolink:NamedThing	phospholipase A2 inhibitor activity	Binds to and stops, prevents or reduces the activity of phospholipase A2.	got7fsn_ti														molecular_function											owl:Class	
GO:0050601	biolink:NamedThing	myristoyl-CoA 11-(Z) desaturase activity	Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O.	got7fsn_ti	Z/E11-desaturase|fatty acid delta(11)-desaturase|delta(11)-palmitoyl-CoA desaturase|delta(11)-fatty-acid desaturase|delta(11) desaturase											MetaCyc:1.14.99.32-RXN|RHEA:25852|EC:1.14.19.5		molecular_function											owl:Class	
GO:0009007	biolink:NamedThing	site-specific DNA-methyltransferase (adenine-specific) activity	Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.	got7fsn_ti	N-6 adenine-specific DNA methylase activity|EcoRI methylase|DNA adenine methylase|restriction-modification system activity|modification methylase activity											EC:2.1.1.72|MetaCyc:2.1.1.72-RXN|RHEA:15197		molecular_function											owl:Class	
GO:0048139	biolink:NamedThing	female germ-line cyst encapsulation	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad.	got7fsn_ti														biological_process											owl:Class	
GO:0048138	biolink:NamedThing	germ-line cyst encapsulation	Formation of a single follicular epithelium around the germ-line derived cells of a cyst.	got7fsn_ti														biological_process											owl:Class	
GO:0044631	biolink:NamedThing	positive regulation of complement activation, lectin pathway in other organism	Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism.	got7fsn_ti							jl	2012-07-05T01:17:33Z						biological_process											owl:Class	
GO:0001870	biolink:NamedThing	positive regulation of complement activation, lectin pathway	Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.	got7fsn_ti	upregulation of complement activation, lectin pathway|stimulation of complement activation, lectin pathway|activation of complement activation, lectin pathway|up regulation of complement activation, lectin pathway|positive regulation of complement cascade, lectin pathway|up-regulation of complement activation, lectin pathway													biological_process											owl:Class	
GO:0060843	biolink:NamedThing	venous endothelial cell differentiation	The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.	got7fsn_ti							dph	2009-08-12T10:43:40Z						biological_process											owl:Class	
GO:0072324	biolink:NamedThing	ascus epiplasm	Ascus cytoplasm that is not packaged into ascospores.	got7fsn_ti					Note that this term is an is_a child of 'cell part' because the epiplasm is extracellular to the spore (each of which is a cell) but within the ascus structure, and originated from cytoplasm.		mah	2010-10-28T04:37:46Z						cellular_component											owl:Class	
GO:0007383	biolink:NamedThing	specification of segmental identity, antennal segment	The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti					See also the fly_anatomy.ontology term 'antennal segment ; FBbt:00000009'.									biological_process											owl:Class	
GO:0007380	biolink:NamedThing	specification of segmental identity, head	The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0009302	biolink:NamedThing	sno(s)RNA transcription	The synthesis of snoRNA class RNA (also referred to as sRNA in Archaea) from a DNA template.	got7fsn_ti	sRNA transcription|snoRNA transcription	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0008301	biolink:NamedThing	DNA binding, bending	The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	got7fsn_ti	DNA bending involving DNA binding|DNA bending activity													molecular_function											owl:Class	
GO:0032294	biolink:NamedThing	peripheral nervous system non-myelinated axon ensheathment	The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons.	got7fsn_ti	ensheathment of non-myelinated axons in peripheral nervous system													biological_process											owl:Class	
GO:0032285	biolink:NamedThing	non-myelinated axon ensheathment	The process in which a non-myelinating glial cell membrane closes around an axon.	got7fsn_ti	ensheathment of non-myelinated axons													biological_process											owl:Class	
GO:0044347	biolink:NamedThing	cell wall polysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides.	got7fsn_ti	cell wall polysaccharide breakdown						jl	2011-07-28T01:24:57Z						biological_process											owl:Class	
GO:0016998	biolink:NamedThing	cell wall macromolecule catabolic process	The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.	got7fsn_ti	cell wall breakdown|cell wall catabolism|cellular cell wall macromolecule degradation|cellular cell wall macromolecule catabolic process|cellular cell wall macromolecule breakdown|cell wall degradation|cellular cell wall macromolecule catabolism										GO:0044039			biological_process											owl:Class	
GO:0061516	biolink:NamedThing	monocyte proliferation	The expansion of a monocyte population by cell division.	got7fsn_ti							dph	2013-04-18T13:14:24Z						biological_process											owl:Class	
GO:0004797	biolink:NamedThing	thymidine kinase activity	Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.	got7fsn_ti	ATP:thymidine 5'-phosphotransferase activity|2'-deoxythymidine kinase activity|deoxythymidine kinase (phosphorylating)|thymidine kinase (phosphorylating)											EC:2.7.1.21|MetaCyc:THYKI-RXN|RHEA:19129		molecular_function											owl:Class	
GO:0044383	biolink:NamedThing	host chromosome	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information, occurring within a host cell.	got7fsn_ti							jl	2011-12-13T03:58:38Z						cellular_component											owl:Class	
GO:0033647	biolink:NamedThing	host intracellular organelle	Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														cellular_component											owl:Class	
GO:0090632	biolink:NamedThing	N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity	Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc.	got7fsn_ti	CMP-Neu5Gc synthetase activity						tb	2015-03-19T15:05:54Z						molecular_function											owl:Class	
GO:0061685	biolink:NamedThing	diphthine methylesterase activity	Catalysis of the reaction: diphthine methyl ester + H2O <=> diphthine + H+ + methanol.	got7fsn_ti							dph	2015-03-04T16:00:21Z				EC:3.1.1.97|RHEA:42656		molecular_function											owl:Class	
GO:0001680	biolink:NamedThing	tRNA 3'-terminal CCA addition	Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.	got7fsn_ti	CCA tRNA nucleotidyltransferase activity|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase activity|tRNA adenylyl(cytidylyl)transferase activity|CTP:tRNA cytidylyltransferase activity|ATP(CTP):tRNA nucleotidyltransferase activity|transfer ribonucleic adenylyl (cytidylyl) transferase activity|transfer ribonucleate nucleotidyltransferase activity|ribonucleic cytidylyltransferase activity|ATP(CTP)-tRNA nucleotidyltransferase activity|-C-C-A pyrophosphorylase activity|CCA-adding enzyme, tRNA adenylyltransferase, tRNA cytidylyltransferase, tRNA CCA-pyrophosphorylase activity|CCA-adding enzyme activity|transfer ribonucleate adenylyltransferase activity|transfer ribonucleate adenyltransferase activity|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase activity|tRNA cytidylyltransferase activity|CTP(ATP):tRNA nucleotidyltransferase activity|transfer ribonucleate cytidylyltransferase activity|transfer-RNA nucleotidyltransferase activity|transfer ribonucleic acid nucleotidyl transferase activity|tRNA-nucleotidyltransferase activity|transfer RNA adenylyltransferase activity|tRNA CCA-diphosphorylase activity											MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN|KEGG_REACTION:R09382		biological_process											owl:Class	
GO:0042780	biolink:NamedThing	tRNA 3'-end processing	The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.	got7fsn_ti	tRNA 3' processing													biological_process											owl:Class	
GO:0017096	biolink:NamedThing	acetylserotonin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.	got7fsn_ti	hydroxyindole methyltransferase activity|acetylserotonin methyltransferase activity|N-acetylserotonin O-methyltransferase activity|hydroxyindole O-methyltransferase activity|S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase activity										GO:0017097	MetaCyc:ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN|RHEA:15573|EC:2.1.1.4		molecular_function											owl:Class	
GO:0097667	biolink:NamedThing	SCF-Rcy1/Pof6 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe).	got7fsn_ti							pr	2014-10-06T10:28:09Z						cellular_component											owl:Class	
GO:0102170	biolink:NamedThing	5-epi-aristolochene-1,3-dihydroxylase activity	Catalysis of the reaction: (+)-5-epi-aristolochene + 2 NADPH + 2 H+ + 2 O2 <=> capsidiol + 2 NADP + 2 H2O.	got7fsn_ti												RHEA:28226|MetaCyc:RXN-11908|EC:1.14.14.149		molecular_function											owl:Class	
GO:0030157	biolink:NamedThing	pancreatic juice secretion	The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach.	got7fsn_ti														biological_process											owl:Class	
GO:0050972	biolink:NamedThing	detection of mechanical stimulus involved in echolocation	The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave.	got7fsn_ti	echolocation, sensory detection of mechanical stimulus|sensory detection of mechanical stimulus during echolocation|echolocation, detection of mechanical stimulus|echolocation, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during echolocation													biological_process											owl:Class	
GO:0010635	biolink:NamedThing	regulation of mitochondrial fusion	Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0071744	biolink:NamedThing	IgE B cell receptor complex	An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	got7fsn_ti	membrane-bound IgE|surface IgE				Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0050728	biolink:NamedThing	negative regulation of inflammatory response	Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.	got7fsn_ti	inhibition of inflammatory response|anti-inflammatory response|down-regulation of inflammatory response|down regulation of inflammatory response|downregulation of inflammatory response										GO:0030236			biological_process											owl:Class	
GO:0031348	biolink:NamedThing	negative regulation of defense response	Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.	got7fsn_ti	down regulation of defense response|down-regulation of defense response|inhibition of defense response|downregulation of defense response													biological_process											owl:Class	
GO:0042902	biolink:NamedThing	peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein	The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.	got7fsn_ti												RESID:AA0345		biological_process											owl:Class	
GO:0009033	biolink:NamedThing	trimethylamine-N-oxide reductase activity	Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O.	got7fsn_ti	trimethylamine oxidase activity|trimethylamine N-oxide reductase|trimethylamine oxide reductase|NADH:trimethylamine-N-oxide oxidoreductase											RHEA:22024|MetaCyc:TMAOREDUCT-RXN		molecular_function											owl:Class	
GO:0070295	biolink:NamedThing	renal water absorption	A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	got7fsn_ti	renal water reabsorption|nephron water absorption													biological_process											owl:Class	
GO:0003097	biolink:NamedThing	renal water transport	The directed movement of water (H2O) by the renal system.	got7fsn_ti														biological_process											owl:Class	
GO:1904319	biolink:NamedThing	negative regulation of smooth muscle contraction involved in micturition	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition.	got7fsn_ti	down-regulation of urinary bladder smooth muscle contraction involved in micturition|down regulation of urinary bladder smooth muscle contraction involved in micturition|down-regulation of smooth muscle contraction involved in micturition|inhibition of smooth muscle contraction involved in urination|negative regulation of urinary bladder smooth muscle contraction involved in micturition|down regulation of smooth muscle contraction involved in micturition|downregulation of smooth muscle contraction involved in urination|down regulation of smooth muscle contraction involved in urination|down-regulation of smooth muscle contraction involved in urination|negative regulation of smooth muscle contraction involved in urination|inhibition of urinary bladder smooth muscle contraction involved in micturition|downregulation of urinary bladder smooth muscle contraction involved in micturition|inhibition of smooth muscle contraction involved in micturition|downregulation of smooth muscle contraction involved in micturition						sl	2015-06-10T18:46:17Z						biological_process											owl:Class	
GO:0008098	biolink:NamedThing	5S rRNA primary transcript binding	Binding to an unprocessed 5S ribosomal RNA transcript.	got7fsn_ti														molecular_function											owl:Class	
GO:0008097	biolink:NamedThing	5S rRNA binding	Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome.	got7fsn_ti														molecular_function											owl:Class	
GO:0050505	biolink:NamedThing	hydroquinone glucosyltransferase activity	Catalysis of the reaction: hydroquinone + UDP-D-glucose = H(+) + hydroquinone O-beta-D-glucopyranoside + UDP.	got7fsn_ti	UDPglucose:hydroquinone-O-beta-D-glucosyltransferase activity|hydroquinone:O-glucosyltransferase activity|UDP-glucose:hydroquinone-O-beta-D-glucosyltransferase activity|arbutin synthase activity											RHEA:12560|KEGG_REACTION:R05769|MetaCyc:2.4.1.218-RXN|EC:2.4.1.218		molecular_function											owl:Class	
GO:0061239	biolink:NamedThing	mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti							dph	2010-08-19T03:06:46Z						biological_process											owl:Class	
GO:0072037	biolink:NamedThing	mesenchymal stem cell differentiation involved in nephron morphogenesis	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti							mah	2010-01-25T03:07:39Z						biological_process											owl:Class	
GO:0007253	biolink:NamedThing	cytoplasmic sequestering of NF-kappaB	The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.	got7fsn_ti	maintenance of NF-kappaB location in cytoplasm|cytoplasmic NF-kappaB sequestration|cytoplasmic NF-kappaB retention|cytoplasmic retention of NF-kappaB|cytoplasmic sequestration of NF-kappaB|cytoplasmic NF-kappaB storage|cytoplasmic storage of NF-kappaB													biological_process											owl:Class	
GO:0032088	biolink:NamedThing	negative regulation of NF-kappaB transcription factor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.	got7fsn_ti	inhibition of NF-kappaB transcription factor|NF-kappaB inhibitor													biological_process											owl:Class	
GO:0001878	biolink:NamedThing	response to yeast	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.	got7fsn_ti					defined as response to Saccharomycotina (true yeasts). This excludes fission yeast.									biological_process											owl:Class	
GO:0030224	biolink:NamedThing	monocyte differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.	got7fsn_ti	monocyte cell differentiation													biological_process											owl:Class	
GO:0019241	biolink:NamedThing	citrulline catabolic process	The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.	got7fsn_ti	citrulline degradation|citrulline catabolism|citrulline breakdown											MetaCyc:CITRULLINE-DEG-PWY		biological_process											owl:Class	
GO:0032881	biolink:NamedThing	regulation of polysaccharide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.	got7fsn_ti														biological_process											owl:Class	
GO:0002275	biolink:NamedThing	myeloid cell activation involved in immune response	A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	myeloid cell activation during immune response													biological_process											owl:Class	
GO:0002366	biolink:NamedThing	leukocyte activation involved in immune response	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	immune cell activation during immune response|leucocyte activation during immune response|leukocyte activation during immune response													biological_process											owl:Class	
GO:0044806	biolink:NamedThing	G-quadruplex DNA unwinding	The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.	got7fsn_ti							jl	2013-09-10T16:16:16Z						biological_process											owl:Class	
GO:0032392	biolink:NamedThing	DNA geometric change	The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.	got7fsn_ti					Note that DNA geometric change and DNA topological change (GO:0006265) are distinct, but are usually coupled in vivo.									biological_process											owl:Class	
GO:0017108	biolink:NamedThing	5'-flap endonuclease activity	Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.	got7fsn_ti	5' flap endonuclease activity											Reactome:R-HSA-110363|Reactome:R-HSA-5687664|Reactome:R-HSA-174441|Reactome:R-HSA-174446|Reactome:R-HSA-69152|Reactome:R-HSA-5651782		molecular_function											owl:Class	
GO:0044553	biolink:NamedThing	modulation of biological quality in other organism	Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.	got7fsn_ti	regulation of biological quality in other organism						jl	2012-03-29T02:35:03Z						biological_process											owl:Class	
GO:1903489	biolink:NamedThing	positive regulation of lactation	Any process that activates or increases the frequency, rate or extent of lactation.	got7fsn_ti	up-regulation of lactation|up regulation of lactation|upregulation of lactation|activation of lactation						mr	2014-09-24T14:44:30Z						biological_process											owl:Class	
GO:1903487	biolink:NamedThing	regulation of lactation	Any process that modulates the frequency, rate or extent of lactation.	got7fsn_ti							mr	2014-09-24T14:44:13Z						biological_process											owl:Class	
GO:0018032	biolink:NamedThing	protein amidation	Addition of an amide group from a glycine to a protein amino acid.	got7fsn_ti	protein amino acid amidation													biological_process											owl:Class	
GO:0050654	biolink:NamedThing	chondroitin sulfate proteoglycan metabolic process	The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.	got7fsn_ti	chondroitin sulfate proteoglycan metabolism|chondroitin sulphate proteoglycan metabolic process|chondroitin sulphate proteoglycan metabolism													biological_process											owl:Class	
GO:0006029	biolink:NamedThing	proteoglycan metabolic process	The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	got7fsn_ti	proteoglycan sulfate transfer|proteoglycan metabolism													biological_process											owl:Class	
GO:0097462	biolink:NamedThing	Lewy neurite	Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.	got7fsn_ti							pr	2012-12-21T07:57:58Z				NIF_Subcellular:sao601362597		cellular_component											owl:Class	
GO:0051111	biolink:NamedThing	peptidyl-histidine adenylylation	The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine).	got7fsn_ti												RESID:AA0371		biological_process											owl:Class	
GO:1903055	biolink:NamedThing	positive regulation of extracellular matrix organization	Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.	got7fsn_ti	up-regulation of extracellular matrix organisation|activation of extracellular matrix organization|up regulation of extracellular matrix organisation|up regulation of extracellular matrix organization|up regulation of extracellular matrix organization and biogenesis|activation of extracellular matrix organisation|upregulation of extracellular matrix organization|up-regulation of extracellular matrix organization|upregulation of extracellular matrix organisation|positive regulation of extracellular matrix organisation|positive regulation of extracellular matrix organization and biogenesis|up-regulation of extracellular matrix organization and biogenesis|activation of extracellular matrix organization and biogenesis|upregulation of extracellular matrix organization and biogenesis						rl	2014-05-23T17:15:53Z						biological_process											owl:Class	
GO:0090439	biolink:NamedThing	tetraketide alpha-pyrone synthase activity	Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A .	got7fsn_ti							tb	2012-08-09T14:35:06Z						molecular_function											owl:Class	
GO:0002464	biolink:NamedThing	peripheral tolerance induction to nonself antigen	Tolerance induction to nonself antigens in the periphery.	got7fsn_ti														biological_process											owl:Class	
GO:0002462	biolink:NamedThing	tolerance induction to nonself antigen	Tolerance induction in response to nonself antigens.	got7fsn_ti														biological_process											owl:Class	
GO:0018850	biolink:NamedThing	chloromuconate cycloisomerase activity	Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.	got7fsn_ti	2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)|muconate cycloisomerase II activity											RHEA:11032|EC:5.5.1.7|UM-BBD_enzymeID:e0065		molecular_function											owl:Class	
GO:0004075	biolink:NamedThing	biotin carboxylase activity	Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.	got7fsn_ti	biotin carboxylase (component of acetyl CoA carboxylase) activity|biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming) activity											EC:6.3.4.14|RHEA:13501|MetaCyc:BIOTIN-CARBOXYL-RXN		molecular_function											owl:Class	
GO:0043110	biolink:NamedThing	rDNA spacer replication fork barrier binding	Binding to replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription.	got7fsn_ti	RFB binding													molecular_function											owl:Class	
GO:0031634	biolink:NamedThing	replication fork barrier binding	Binding to replication fork barriers, sites that inhibit the progress of replication forks.	got7fsn_ti														molecular_function											owl:Class	
GO:0055067	biolink:NamedThing	monovalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0018245	biolink:NamedThing	protein O-linked glycosylation via tyrosine	The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen.	got7fsn_ti	protein amino acid O-linked glycosylation via tyrosine											RESID:AA0157		biological_process											owl:Class	
GO:0033855	biolink:NamedThing	nicotianamine aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate.	got7fsn_ti	NAAT-III|NAAT|NAAT-I|NAAT-II|nicotianamine:2-oxoglutarate aminotransferase activity|nicotianamine transaminase activity											KEGG_REACTION:R07277|RHEA:22104|MetaCyc:2.6.1.80-RXN|EC:2.6.1.80		molecular_function											owl:Class	
GO:0072517	biolink:NamedThing	host cell viral assembly compartment	A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place.	got7fsn_ti	virion assembly compartment|viral assembly site|host cell virion assembly compartment|host cell viral assembly site|viral assembly compartment						mah	2010-12-21T03:08:42Z			GO:0072516			cellular_component											owl:Class	
GO:0035847	biolink:NamedThing	uterine epithelium development	The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	got7fsn_ti	uterus epithelial development						bf	2011-05-10T10:57:45Z						biological_process											owl:Class	
GO:0016822	biolink:NamedThing	hydrolase activity, acting on acid carbon-carbon bonds	Catalysis of the hydrolysis of any acid carbon-carbon bond.	got7fsn_ti												EC:3.7.-.-		molecular_function											owl:Class	
GO:0005725	biolink:NamedThing	intercalary heterochromatin	Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes.	got7fsn_ti														cellular_component											owl:Class	
GO:0000792	biolink:NamedThing	heterochromatin	A compact and highly condensed form of chromatin.	got7fsn_ti	nuclear heterochromatin										GO:0005720	Wikipedia:Heterochromatin|NIF_Subcellular:sao581845896		cellular_component											owl:Class	
GO:0038130	biolink:NamedThing	ERBB4 signaling pathway	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	receptor tyrosine-protein kinase erbB-4 signaling pathway|ERBB4 signalling pathway|HER4 signaling pathway						bf	2012-03-30T10:44:08Z						biological_process											owl:Class	
GO:0051364	biolink:NamedThing	N-terminal peptidyl-proline N-formylation	The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.	got7fsn_ti												RESID:AA0384		biological_process											owl:Class	
GO:0031831	biolink:NamedThing	type 5B serotonin receptor binding	Binding to a type 5B serotonin receptor.	got7fsn_ti	type 5B serotonin receptor ligand|5-hydroxytryptamine 5B receptor binding													molecular_function											owl:Class	
GO:0014862	biolink:NamedThing	regulation of skeletal muscle contraction by chemo-mechanical energy conversion	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres.	got7fsn_ti														biological_process											owl:Class	
GO:0014819	biolink:NamedThing	regulation of skeletal muscle contraction	Any process that modulates the frequency, rate or extent of skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0035665	biolink:NamedThing	TIRAP-dependent toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	got7fsn_ti	TIRAP-dependent TLR4 signaling pathway|MAL-dependent toll-like receptor 4 signaling pathway|MyD88 adapter-like dependent toll-like receptor 4 signaling pathway|TIRAP-dependent toll-like receptor 4 signalling pathway						bf	2011-02-01T02:33:48Z						biological_process											owl:Class	
GO:0051670	biolink:NamedThing	inulinase activity	Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin.	got7fsn_ti	exoinulinase activity|inulase activity|endo-inulinase activity|2,1-beta-D-fructan fructanohydrolase activity|indoinulinase activity											EC:3.2.1.7|MetaCyc:3.2.1.7-RXN		molecular_function											owl:Class	
GO:0051126	biolink:NamedThing	negative regulation of actin nucleation	Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.	got7fsn_ti	downregulation of actin nucleation|inhibition of actin nucleation|down regulation of actin nucleation|down-regulation of actin nucleation													biological_process											owl:Class	
GO:0051494	biolink:NamedThing	negative regulation of cytoskeleton organization	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.	got7fsn_ti	down regulation of cytoskeleton organization|down-regulation of cytoskeleton organization|inhibition of cytoskeleton organization|negative regulation of cytoskeleton organization and biogenesis|negative regulation of cytoskeleton organisation|downregulation of cytoskeleton organization													biological_process											owl:Class	
GO:0034408	biolink:NamedThing	ascospore wall beta-glucan metabolic process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.	got7fsn_ti	ascospore wall beta-glucan metabolism													biological_process											owl:Class	
GO:0070879	biolink:NamedThing	fungal-type cell wall beta-glucan metabolic process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.	got7fsn_ti	fungal-type cell wall beta-glucan metabolism						mah	2009-08-21T02:46:09Z						biological_process											owl:Class	
GO:0018067	biolink:NamedThing	peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine	The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA).	got7fsn_ti	peptidyl-L-3',4'-dihydroxyphenylalanine synthesis from peptidyl-tyrosine|peptidyl-L-3',4'-dihydroxyphenylalanine anabolism from peptidyl-tyrosine|peptidyl-L-3',4'-dihydroxyphenylalanine formation from peptidyl-tyrosine											RESID:AA0146		biological_process											owl:Class	
GO:0035369	biolink:NamedThing	pre-B cell receptor complex	An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	got7fsn_ti	pre-BCR				Despite its name, the pre-BCR is not a receptor complex, as it appears to provide a low level of signal not dependent on a ligand, but rather simply on correct assembly of the complex as a measure for correct Ig heavy chain recombination and folding. A significant proportion of pre-BCR complexes fail to reach the cell surface, and in some cases may provide their signaling function from the trans-Golgi network or lysosome.		bf	2010-03-11T10:46:10Z						cellular_component											owl:Class	
GO:0050802	biolink:NamedThing	circadian sleep/wake cycle, sleep	The part of the circadian sleep/wake cycle where the organism is asleep.	got7fsn_ti														biological_process											owl:Class	
GO:0097003	biolink:NamedThing	adipokinetic hormone receptor activity	Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.	got7fsn_ti	AKH receptor activity						pr	2011-03-14T10:24:08Z						molecular_function											owl:Class	
GO:0080015	biolink:NamedThing	sabinene synthase activity	Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate.	got7fsn_ti												MetaCyc:RXN-5103|EC:4.2.3.-		molecular_function											owl:Class	
GO:0080178	biolink:NamedThing	5-carbamoylmethyl uridine residue modification	The chemical reactions and pathways involving the addition of a  5-carbamoylmethyl group to a uridine residue in RNA.	got7fsn_ti	5-carbamoylmethyluridine metabolic process						dhl	2011-04-28T04:36:23Z						biological_process											owl:Class	
GO:0043174	biolink:NamedThing	nucleoside salvage	Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0007443	biolink:NamedThing	Malpighian tubule morphogenesis	The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.	got7fsn_ti					See also the fly_anatomy.ontology term 'Malpighian tubule ; FBbt:00005786'.									biological_process											owl:Class	
GO:0061333	biolink:NamedThing	renal tubule morphogenesis	The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.	got7fsn_ti							dph	2010-09-28T01:43:04Z						biological_process											owl:Class	
GO:0102782	biolink:NamedThing	cholestanol hydroxylase activity	Catalysis of the reaction: H+ + epidihydrocholesterin + O2 + NADPH = (22alpha)-hydroxy-cholestanol + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-7878		molecular_function											owl:Class	
GO:0002870	biolink:NamedThing	T cell anergy	Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.	got7fsn_ti	T lymphocyte anergy|T-lymphocyte anergy|T-cell anergy													biological_process											owl:Class	
GO:0002249	biolink:NamedThing	lymphocyte anergy	Any process contributing to lymphocyte anergy, a state of functional inactivation.	got7fsn_ti														biological_process											owl:Class	
GO:0050484	biolink:NamedThing	GMP 5'-nucleotidase activity	Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate.	got7fsn_ti	IMP-GMP specific 5'-nucleotidase activity|GMP 5' nucleotidase activity											MetaCyc:RXN-7609|RHEA:27714		molecular_function											owl:Class	
GO:0008253	biolink:NamedThing	5'-nucleotidase activity	Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.	got7fsn_ti	5'-AMP nucleotidase|5'-ribonucleotide phosphohydrolase activity|adenosine monophosphatase|adenosine 5'-phosphatase|snake venom 5'-nucleotidase|5'-mononucleotidase activity|thimidine monophosphate nucleotidase|AMP phosphohydrolase|AMP phosphatase|5'-adenylic phosphatase|5' nucleotidase activity|AMPase|5'-AMPase|UMPase|uridine 5'-nucleotidase											Reactome:R-HSA-8940074|Reactome:R-HSA-109480|MetaCyc:5-NUCLEOTID-RXN|Reactome:R-HSA-109380|Reactome:R-HSA-109415|Reactome:R-HSA-109387|Reactome:R-HSA-5694126|Reactome:R-HSA-109449|Reactome:R-HSA-109514|RHEA:12484|Reactome:R-HSA-74248|Reactome:R-HSA-109470|Reactome:R-HSA-8940070|EC:3.1.3.5|Reactome:R-HSA-109278|Reactome:R-HSA-109291		molecular_function											owl:Class	
GO:0001875	biolink:NamedThing	lipopolysaccharide immune receptor activity	Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.	got7fsn_ti	lipopolysaccharide receptor activity|endotoxin receptor activity|LPS receptor activity													molecular_function											owl:Class	
GO:0038187	biolink:NamedThing	pattern recognition receptor activity	Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.	got7fsn_ti	microbe-associated molecular pattern receptor activity|PAMP receptor activity|PRR activity|PRR|MAMP receptor activity|pathogen associated molecular pattern receptor activity|signaling pattern recognition receptor activity|macrophage receptor activity	https://github.com/geneontology/go-ontology/issues/17995|https://github.com/geneontology/go-ontology/issues/18588					bf	2013-05-29T15:24:44Z			GO:0008329	Wikipedia:Pattern_recognition_receptor		molecular_function											owl:Class	
GO:0035749	biolink:NamedThing	myelin sheath adaxonal region	The region of the myelin sheath nearest to the axon.	got7fsn_ti							bf	2011-03-23T10:17:42Z						cellular_component											owl:Class	
GO:0051938	biolink:NamedThing	L-glutamate import	The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.	got7fsn_ti	L-glutamate uptake													biological_process											owl:Class	
GO:0070029	biolink:NamedThing	alphav-beta3 integrin-osteopontin complex	A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.	got7fsn_ti	ITGAV-ITGB3-SPP1 complex													cellular_component											owl:Class	
GO:0002330	biolink:NamedThing	pre-B cell receptor expression	The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the  association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.	got7fsn_ti														biological_process											owl:Class	
GO:0042613	biolink:NamedThing	MHC class II protein complex	A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.	got7fsn_ti														cellular_component											owl:Class	
GO:0042611	biolink:NamedThing	MHC protein complex	A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.	got7fsn_ti														cellular_component											owl:Class	
GO:0009563	biolink:NamedThing	synergid differentiation	The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell.	got7fsn_ti	synergid cell differentiation													biological_process											owl:Class	
GO:0070465	biolink:NamedThing	alpha1-beta1 integrin-alpha3(VI) complex	A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.	got7fsn_ti	ITGA1-ITGB1-COL6A3 complex													cellular_component											owl:Class	
GO:0048810	biolink:NamedThing	female analia morphogenesis	The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0070930	biolink:NamedThing	trans-translation-dependent protein tagging	A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.	got7fsn_ti	protein modification by trans-translation|cotranslational protein tagging|co-translational protein tagging				Note that this term is not a child of 'co-translational protein modification process ; GO:0043686' because co-translational protein modification implies modification of a previously incorporated amino acid in a nascent chain, rather than addition of new sequence to the C-terminus.		mah	2009-09-16T04:10:49Z						biological_process											owl:Class	
GO:0018534	biolink:NamedThing	nitrilotriacetate dehydrogenase activity	Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate.	got7fsn_ti												EC:1.5.99.-|UM-BBD_reactionID:r0588		molecular_function											owl:Class	
GO:0018025	biolink:NamedThing	calmodulin-lysine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.	got7fsn_ti	S-adenosylmethionine:calmodulin (lysine) N-methyltransferase activity|S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase activity|S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase activity											EC:2.1.1.60|MetaCyc:2.1.1.60-RXN|Reactome:R-HSA-6786205|RHEA:21556		molecular_function											owl:Class	
GO:0016279	biolink:NamedThing	protein-lysine N-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.	got7fsn_ti												Reactome:R-HSA-212263|Reactome:R-HSA-8932276|Reactome:R-HSA-8865237|Reactome:R-HSA-8932275|Reactome:R-HSA-8932413|Reactome:R-HSA-8931974|Reactome:R-HSA-8932221|Reactome:R-HSA-8932243|Reactome:R-HSA-8931858		molecular_function											owl:Class	
GO:0030331	biolink:NamedThing	estrogen receptor binding	Binding to an estrogen receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0021576	biolink:NamedThing	hindbrain formation	The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.	got7fsn_ti														biological_process											owl:Class	
GO:0042702	biolink:NamedThing	uterine wall growth	The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels.	got7fsn_ti														biological_process											owl:Class	
GO:0045962	biolink:NamedThing	positive regulation of development, heterochronic	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached.	got7fsn_ti	stimulation of development, heterochronic|up-regulation of development, heterochronic|activation of development, heterochronic|upregulation of development, heterochronic|up regulation of development, heterochronic													biological_process											owl:Class	
GO:0040034	biolink:NamedThing	regulation of development, heterochronic	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.	got7fsn_ti	developmental timing|heterochronic regulation of development|temporal regulation of development													biological_process											owl:Class	
GO:0102003	biolink:NamedThing	Delta8-sphingolipid desaturase activity	Catalysis of the reaction: phytosphingosine(1+) + O2 + a reduced electron acceptor <=> 4-hydroxy-trans-8-sphingenine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.4|MetaCyc:1.14.19.4-RXN		molecular_function											owl:Class	
GO:0052631	biolink:NamedThing	sphingolipid delta-8 desaturase activity	Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).	got7fsn_ti												RHEA:46268|MetaCyc:RXN-7798		molecular_function											owl:Class	
GO:0043079	biolink:NamedThing	antipodal cell nucleus	The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents.	got7fsn_ti														cellular_component											owl:Class	
GO:0106303	biolink:NamedThing	mannogen metabolic process	The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.	got7fsn_ti	mannogen metabolism|beta-1,2-mannan metabolic process						hjd	2020-09-09T13:49:42Z						biological_process											owl:Class	
GO:0043604	biolink:NamedThing	amide biosynthetic process	The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.	got7fsn_ti														biological_process											owl:Class	
GO:0035751	biolink:NamedThing	regulation of lysosomal lumen pH	Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.	got7fsn_ti							bf	2011-03-23T10:23:41Z						biological_process											owl:Class	
GO:0051453	biolink:NamedThing	regulation of intracellular pH	Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.	got7fsn_ti	pH regulation in cell|regulation of cell pH|cell pH regulation|cellular pH regulation													biological_process											owl:Class	
GO:0033783	biolink:NamedThing	25-hydroxycholesterol 7alpha-hydroxylase activity	Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.	got7fsn_ti	CYP7B1 oxysterol 7alpha-hydroxylase activity|25-hydroxycholesterol 7alpha-monooxygenase activity|cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity|CYP7B1											MetaCyc:RXN-7981|RHEA:19041|MetaCyc:RXN-7980|EC:1.14.14.29		molecular_function											owl:Class	
GO:0018890	biolink:NamedThing	cyanamide metabolic process	The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.	got7fsn_ti	cyanamide metabolism											UM-BBD_pathwayID:cnm		biological_process											owl:Class	
GO:0071178	biolink:NamedThing	MAML2-RBP-Jkappa-ICN4 complex	A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML2-RBP-Jkappa-Notch4 complex						mah	2009-11-23T02:49:21Z						cellular_component											owl:Class	
GO:0103086	biolink:NamedThing	methylthiopentylmalate isomerase activity	Catalysis of the reaction: 2-(5'-methylthio)pentylmalate <=> 3-(5'-methylthio)pentylmalate.	got7fsn_ti												MetaCyc:RXNQT-4170		molecular_function											owl:Class	
GO:0106045	biolink:NamedThing	guanine deglycation, methylglyoxal removal	The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine.	got7fsn_ti							hjd	2017-08-01T18:17:28Z						biological_process											owl:Class	
GO:0106044	biolink:NamedThing	guanine deglycation	The removal of a sugar or dicarbonyl from a glycated guanine.	got7fsn_ti							hjd	2017-08-01T18:15:28Z						biological_process											owl:Class	
GO:0033072	biolink:NamedThing	vancomycin biosynthetic process	The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.	got7fsn_ti	vancomycin anabolism|vancomycin biosynthesis|vancomycin formation|vancomycin synthesis													biological_process											owl:Class	
GO:0019184	biolink:NamedThing	nonribosomal peptide biosynthetic process	The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.	got7fsn_ti	nonribosomal peptide biosynthesis|non-ribosomal peptide formation|non-ribosomal peptide synthesis|nonribosomal peptide synthesis|non-ribosomal peptide biosynthetic process|nonribosomal peptide anabolism|nonribosomal peptide synthetase|non-ribosomal peptide biosynthesis|nonribosomal peptide formation													biological_process											owl:Class	
GO:0034525	biolink:NamedThing	1-naphthaldehyde dehydrogenase activity	Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r0787		molecular_function											owl:Class	
GO:0034587	biolink:NamedThing	piRNA metabolic process	The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	got7fsn_ti	Piwi-associated RNA metabolic process|piRNA metabolism													biological_process											owl:Class	
GO:0034660	biolink:NamedThing	ncRNA metabolic process	The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs).	got7fsn_ti	ncRNA metabolism													biological_process											owl:Class	
GO:0009682	biolink:NamedThing	induced systemic resistance	A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling.	got7fsn_ti														biological_process											owl:Class	
GO:0005164	biolink:NamedThing	tumor necrosis factor receptor binding	Binding to a tumor necrosis factor receptor.	got7fsn_ti	TNF receptor binding|tumor necrosis factor|tumor necrosis factor receptor ligand													molecular_function											owl:Class	
GO:0032813	biolink:NamedThing	tumor necrosis factor receptor superfamily binding	Binding to a member of the tumor necrosis factor receptor superfamily.	got7fsn_ti	TNF receptor superfamily binding													molecular_function											owl:Class	
GO:0055105	biolink:NamedThing	ubiquitin-protein transferase inhibitor activity	Binds to and stops, prevents or reduces the activity of a ubiquitin-protein transferase.	got7fsn_ti														molecular_function											owl:Class	
GO:0097486	biolink:NamedThing	multivesicular body lumen	The volume enclosed by the outermost membrane of a multivesicular body.	got7fsn_ti							pr	2013-07-08T20:32:56Z						cellular_component											owl:Class	
GO:0031906	biolink:NamedThing	late endosome lumen	The volume enclosed by the membrane of a late endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0009165	biolink:NamedThing	nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).	got7fsn_ti	nucleotide formation|nucleotide anabolism|nucleotide biosynthesis|nucleotide synthesis													biological_process											owl:Class	
GO:0071482	biolink:NamedThing	cellular response to light stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.	got7fsn_ti							mah	2009-12-18T02:03:49Z						biological_process											owl:Class	
GO:0031814	biolink:NamedThing	P2Y4 nucleotide receptor binding	Binding to a P2Y4 nucleotide receptor.	got7fsn_ti	P2Y4 nucleotide receptor ligand													molecular_function											owl:Class	
GO:1990071	biolink:NamedThing	TRAPPII protein complex	A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself.	got7fsn_ti							bhm	2013-03-28T14:24:08Z						cellular_component											owl:Class	
GO:0030008	biolink:NamedThing	TRAPP complex	A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.	got7fsn_ti	TRAPP2|transport protein particle|TRAPP1|transport protein particle complex											Wikipedia:TRAPP_complex		cellular_component											owl:Class	
GO:0033517	biolink:NamedThing	myo-inositol hexakisphosphate metabolic process	The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.	got7fsn_ti	phytate metabolism|phytate metabolic process|myo-inositol hexakisphosphate metabolism													biological_process											owl:Class	
GO:0046956	biolink:NamedThing	positive phototaxis	The directed movement of a cell or organism towards a source of light.	got7fsn_ti	positive phototactic behavior|positive taxis in response to light|positive phototactic behaviour										GO:0046954			biological_process											owl:Class	
GO:0036215	biolink:NamedThing	response to stem cell factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.	got7fsn_ti	response to hematopoietic growth factor KL|response to KIT ligand|response to stem cell factor stimulus|response to SCF						bf	2012-04-27T10:26:37Z						biological_process											owl:Class	
GO:0034848	biolink:NamedThing	naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity	Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r1261		molecular_function											owl:Class	
GO:0047422	biolink:NamedThing	N-acyl-D-aspartate deacylase activity	Catalysis of the reaction: N-acyl-D-aspartate + H(2)O = D-aspartate + a carboxylate.	got7fsn_ti	N-acyl-D-aspartate amidohydrolase activity											RHEA:18285|KEGG_REACTION:R02182|MetaCyc:3.5.1.83-RXN|EC:3.5.1.83		molecular_function											owl:Class	
GO:2000196	biolink:NamedThing	positive regulation of female gonad development	Any process that activates or increases the frequency, rate or extent of female gonad development.	got7fsn_ti	positive regulation of ovarian development|positive regulation of ovary development						yaf	2010-10-19T10:45:41Z						biological_process											owl:Class	
GO:2000243	biolink:NamedThing	positive regulation of reproductive process	Any process that activates or increases the frequency, rate or extent of reproductive process.	got7fsn_ti							mah	2010-11-10T02:44:08Z						biological_process											owl:Class	
GO:0021654	biolink:NamedThing	rhombomere boundary formation	The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0035333	biolink:NamedThing	Notch receptor processing, ligand-dependent	The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD).	got7fsn_ti	Notch S2 cleavage|Notch S3 cleavage						bf	2010-02-26T02:31:31Z						biological_process											owl:Class	
GO:0031293	biolink:NamedThing	membrane protein intracellular domain proteolysis	The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.	got7fsn_ti	membrane protein solubilization													biological_process											owl:Class	
GO:0150060	biolink:NamedThing	amylin receptor 2 signaling pathway	A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM).	got7fsn_ti	AMY2 signaling pathway						bc	2018-06-21T11:00:22Z						biological_process											owl:Class	
GO:0097647	biolink:NamedThing	amylin receptor signaling pathway	A series of molecular signals initiated by an extracellular amylin combining with a dimeric amylin receptor on the surface of the target cell.	got7fsn_ti	amilyn receptor signalling pathway						pr	2014-09-09T17:49:52Z						biological_process											owl:Class	
GO:0038115	biolink:NamedThing	chemokine (C-C motif) ligand 19 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	C-C chemokine receptor type 7 signaling pathway|chemokine (C-C motif) ligand 19 signalling pathway|CCL19-mediated signaling pathway				The C-C chemokine CCL19 s a known agonist of the chemokine receptor type 7 (CCR7). Consider instead annotating to the child term 'CCL19-activated CCR7 signaling pathway ; GO:0038119'.		bf	2012-03-22T11:28:32Z						biological_process											owl:Class	
GO:0070098	biolink:NamedThing	chemokine-mediated signaling pathway	A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	chemokine-mediated signalling pathway													biological_process											owl:Class	
GO:0039528	biolink:NamedThing	cytoplasmic pattern recognition receptor signaling pathway in response to virus	Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	got7fsn_ti	RIG-I/MDA5 signaling pathway|virus-induced cytoplasmic pattern recognition receptor signaling pathway|RIG-like receptor signaling pathway|RLR signaling pathway|RLH signaling pathway|cytoplasmic pattern recognition receptor signalling pathway in response to virus|cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway|RIG-like helicase signaling pathway|RIG-I-like receptor (RLR) signaling pathway				This term should be used for annotation when it is not known which cytoplasmic pattern recognition receptor (PRR) has detected the viral RNA. If the PRR is known, consider instead the child terms. The RIG-like family is composed of at least RIG-I (retinoic acid inducible gene I; also known as DDX58), melanoma differentiation-associated gene 5 (MDA5; also known as helicard or IFIH1) and LGP2.		bf	2011-12-20T02:43:15Z						biological_process											owl:Class	
GO:0098586	biolink:NamedThing	cellular response to virus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.	got7fsn_ti							dos	2014-01-24T14:54:08Z						biological_process											owl:Class	
GO:0019516	biolink:NamedThing	lactate oxidation	The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons.	got7fsn_ti														biological_process											owl:Class	
GO:0031001	biolink:NamedThing	response to brefeldin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0046677	biolink:NamedThing	response to antibiotic	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.	got7fsn_ti	antibiotic susceptibility/resistance													biological_process											owl:Class	
GO:0102210	biolink:NamedThing	rhamnogalacturonan endolyase activity	Catalysis of the reaction: H2O + a rhamnogalacturonan type I <=> [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide].	got7fsn_ti												EC:4.2.2.23|MetaCyc:RXN-12173		molecular_function											owl:Class	
GO:0016837	biolink:NamedThing	carbon-oxygen lyase activity, acting on polysaccharides	Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.	got7fsn_ti												EC:4.2.2.-		molecular_function											owl:Class	
GO:0005589	biolink:NamedThing	collagen type VI trimer	A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0072564	biolink:NamedThing	blood microparticle formation	The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell.	got7fsn_ti	microparticle generation|microparticle release						mah	2011-01-28T02:15:50Z						biological_process											owl:Class	
GO:0048290	biolink:NamedThing	isotype switching to IgA isotypes	The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.	got7fsn_ti	isotype switch recombination to IgA isotypes|class switching to IgA isotypes													biological_process											owl:Class	
GO:0045190	biolink:NamedThing	isotype switching	The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.	got7fsn_ti	class switch recombination|class switching|isotype switch recombination				Note that IgM and IgD can be coexpressed by B cells via an alternate splicing mechanism, but true recombinational isotype switching to IgD has been demonstrated as well. Note that this term is best used to annotate gene products which are involved in the mechanism of DNA recombination used in isotype switching, like the B cell specific Swap70 factor in the mouse, rather than gene products which promote isotype switching such as cytokines or co-stimulatory molecules, which should instead be annotated to 'regulation of isotype switching ; GO:0045191'.							Wikipedia:Immunoglobulin_class_switching		biological_process											owl:Class	
GO:0004825	biolink:NamedThing	methionine-tRNA ligase activity	Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).	got7fsn_ti	methionyl-tRNA synthetase activity|methionyl-transfer RNA synthetase activity|methionine translase activity|methionyl-transfer ribonucleic acid synthetase activity|methionyl-transfer ribonucleate synthetase activity|L-methionine:tRNAMet ligase (AMP-forming)|MetRS activity											EC:6.1.1.10|RHEA:13481|MetaCyc:METHIONINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379994|Reactome:R-HSA-380157		molecular_function											owl:Class	
GO:0102053	biolink:NamedThing	(-)-jasmonoyl-isoleucine synthetase activity	Catalysis of the reaction: (-)-jasmonate + L-isoleucine  + ATP(4-) <=> H+ + (-)-jasmonoyl-L-isoleucine + AMP(2-) + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10435		molecular_function											owl:Class	
GO:0006286	biolink:NamedThing	base-excision repair, base-free sugar-phosphate removal	Excision of the sugar phosphate residue at an AP site, i.e. a deoxyribose sugar with a missing base, by a phosphodiesterase enzyme.	got7fsn_ti														biological_process											owl:Class	
GO:0032996	biolink:NamedThing	Bcl3-Bcl10 complex	A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus.	got7fsn_ti														cellular_component											owl:Class	
GO:0033176	biolink:NamedThing	proton-transporting V-type ATPase complex	A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.	got7fsn_ti	hydrogen-translocating V-type ATPase complex													cellular_component											owl:Class	
GO:0034287	biolink:NamedThing	detection of monosaccharide stimulus	The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal.	got7fsn_ti	perception of monosaccharide stimulus													biological_process											owl:Class	
GO:0034284	biolink:NamedThing	response to monosaccharide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.	got7fsn_ti	response to monosaccharide stimulus													biological_process											owl:Class	
GO:0010816	biolink:NamedThing	calcitonin catabolic process	The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.	got7fsn_ti														biological_process											owl:Class	
GO:0018660	biolink:NamedThing	4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity	Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O.	got7fsn_ti	4 HPA 3-hydroxylase activity|p-hydroxyphenylacetate hydroxylase activity|4-hydroxyphenylacetate 3-hydroxylase activity|4-hydroxyphenylacetate 3-monooxygenase activity|p-hydroxyphenylacetate 3-hydroxylase activity											KEGG_REACTION:R02698|EC:1.14.14.9|RHEA:16681		molecular_function											owl:Class	
GO:0034232	biolink:NamedThing	ascospore wall chitin catabolic process	The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.	got7fsn_ti	ascospore wall chitin degradation|ascospore wall chitin breakdown|ascospore wall chitin catabolism													biological_process											owl:Class	
GO:0071854	biolink:NamedThing	cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly	The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall.	got7fsn_ti							mah	2010-09-10T03:12:08Z						biological_process											owl:Class	
GO:0008192	biolink:NamedThing	RNA guanylyltransferase activity	Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0036354	biolink:NamedThing	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity	Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+.	got7fsn_ti							bf	2012-09-19T14:46:31Z				RHEA:19733|MetaCyc:RXN-8787		molecular_function											owl:Class	
GO:0002372	biolink:NamedThing	myeloid dendritic cell cytokine production	Any process that contributes to cytokine production by a myeloid dendritic cell.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0061082	biolink:NamedThing	myeloid leukocyte cytokine production	Any process that contributes to cytokine production by a myeloid cell.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		dph	2010-04-13T11:29:42Z						biological_process											owl:Class	
GO:0000719	biolink:NamedThing	photoreactive repair	The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.	got7fsn_ti	pyrimidine-dimer repair by photolyase													biological_process											owl:Class	
GO:0006290	biolink:NamedThing	pyrimidine dimer repair	The repair of UV-induced T-T, C-T and C-C dimers.	got7fsn_ti														biological_process											owl:Class	
GO:0010943	biolink:NamedThing	NADPH pyrophosphatase activity	Catalysis of the reaction: NADPH + H2O = NMNH + ADP.	got7fsn_ti														molecular_function											owl:Class	
GO:0004551	biolink:NamedThing	nucleotide diphosphatase activity	Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.	got7fsn_ti	nucleotide pyrophosphatase activity|nucleotide-sugar pyrophosphatase activity|dinucleotide nucleotidohydrolase activity											Reactome:R-HSA-196955|MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN|EC:3.6.1.9		molecular_function											owl:Class	
GO:0051604	biolink:NamedThing	protein maturation	Any process leading to the attainment of the full functional capacity of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0015869	biolink:NamedThing	protein-DNA complex transport	The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	DNA-protein complex transport													biological_process											owl:Class	
GO:0006886	biolink:NamedThing	intracellular protein transport	The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.	got7fsn_ti	copper-induced intracellular protein transport										GO:0032779			biological_process											owl:Class	
GO:0007440	biolink:NamedThing	foregut morphogenesis	The process in which the anatomical structures of the foregut are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0018257	biolink:NamedThing	peptidyl-lysine formylation	The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine.	got7fsn_ti												RESID:AA0211		biological_process											owl:Class	
GO:0018256	biolink:NamedThing	protein formylation	The addition of a formyl group to a protein amino acid.	got7fsn_ti	protein amino acid formylation													biological_process											owl:Class	
GO:1990127	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti							pr	2013-06-19T13:55:06Z						biological_process											owl:Class	
GO:0008627	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to osmotic stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	induction of apoptosis by ionic changes													biological_process											owl:Class	
GO:0010069	biolink:NamedThing	zygote asymmetric cytokinesis in embryo sac	The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti														biological_process											owl:Class	
GO:0010070	biolink:NamedThing	zygote asymmetric cell division	The division of the zygote into two daughter cells that will adopt developmentally distinct potentials.	got7fsn_ti	zygote asymmetric cytokinesis													biological_process											owl:Class	
GO:0070725	biolink:NamedThing	Yb body	A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell.	got7fsn_ti							mah	2009-06-15T05:17:28Z						cellular_component											owl:Class	
GO:0009915	biolink:NamedThing	phloem sucrose loading	The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink.	got7fsn_ti														biological_process											owl:Class	
GO:0110126	biolink:NamedThing	phloem loading	The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink.	got7fsn_ti							kmv	2018-09-07T21:24:54Z						biological_process											owl:Class	
GO:0042792	biolink:NamedThing	mitochondrial rRNA transcription	The synthesis of ribosomal RNA (rRNA) from a mitochondrial DNA template.	got7fsn_ti	rRNA transcription from mitochondrial promoter													biological_process											owl:Class	
GO:0006390	biolink:NamedThing	mitochondrial transcription	The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.	got7fsn_ti	transcription from mitochondrial promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0021706	biolink:NamedThing	locus ceruleus maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.	got7fsn_ti														biological_process											owl:Class	
GO:0051732	biolink:NamedThing	polyribonucleotide kinase activity	Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA.	got7fsn_ti	5'-hydroxyl polyribonucleotide kinase activity|RNA kinase activity|5'-hydroxyl RNA kinase activity|RNA 5'-hydroxyl kinase activity													molecular_function											owl:Class	
GO:0051731	biolink:NamedThing	polynucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.	got7fsn_ti	polynucleotide kinase activity|5'-hydroxyl polynucleotide kinase activity|5'-dephosphopolynucleotide kinase activity|polynucleotide 5'-hydroxy-kinase activity|PNK|polynucleotide 5'-hydroxyl kinase (phosphorylating) activity													molecular_function											owl:Class	
GO:0032920	biolink:NamedThing	putrescine acetylation	The modification of putrescine by addition of acetyl groups.	got7fsn_ti														biological_process											owl:Class	
GO:0009445	biolink:NamedThing	putrescine metabolic process	The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine.	got7fsn_ti	putrescine metabolism													biological_process											owl:Class	
GO:0061503	biolink:NamedThing	tRNA threonylcarbamoyladenosine dehydratase	Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.	got7fsn_ti							dph	2013-01-22T14:22:14Z						molecular_function											owl:Class	
GO:0061910	biolink:NamedThing	autophagosome-endosome fusion	The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome.	got7fsn_ti							dph	2017-06-29T17:10:43Z						biological_process											owl:Class	
GO:0061774	biolink:NamedThing	cohesin unloading	Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA.	got7fsn_ti	DNA exit from the cohesin ring						dph	2016-07-13T12:40:25Z						biological_process											owl:Class	
GO:0045875	biolink:NamedThing	negative regulation of sister chromatid cohesion	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.	got7fsn_ti	down-regulation of sister chromatid cohesion|inhibition of sister chromatid cohesion|down regulation of sister chromatid cohesion|downregulation of sister chromatid cohesion													biological_process											owl:Class	
GO:0034957	biolink:NamedThing	3-nitrophenol nitroreductase activity	Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O.	got7fsn_ti												UM-BBD_reactionID:r1495		molecular_function											owl:Class	
GO:0046857	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP.	got7fsn_ti												EC:1.7.1.-		molecular_function											owl:Class	
GO:0034967	biolink:NamedThing	Set3 complex	A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p.	got7fsn_ti	HDAC3 complex|SET3C													cellular_component											owl:Class	
GO:0047337	biolink:NamedThing	dolichyl-diphosphate-polyphosphate phosphotransferase activity	Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate.	got7fsn_ti	dolichyl-diphosphate:polyphosphate phosphotransferase activity|dolichylpyrophosphate:polyphosphate phosphotransferase activity											EC:2.7.4.20|RHEA:19417|MetaCyc:2.7.4.20-RXN		molecular_function											owl:Class	
GO:0007637	biolink:NamedThing	proboscis extension reflex	The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.	got7fsn_ti	proboscis extension in response to nutritional stimulus|behavioral response to nutritional stimulus, proboscis extension													biological_process											owl:Class	
GO:0061653	biolink:NamedThing	ISG15 conjugating enzyme activity	Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y -> Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2						dph	2014-11-06T13:24:50Z						molecular_function											owl:Class	
GO:0007488	biolink:NamedThing	histoblast morphogenesis	The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen.	got7fsn_ti	histoblast metamorphosis													biological_process											owl:Class	
GO:0102130	biolink:NamedThing	malonyl-CoA methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + a malonyl-[acp] = S-adenosyl-L-homocysteine  + a malonyl-[acp] methyl ester.	got7fsn_ti												EC:2.1.1.197|MetaCyc:RXN-11475|RHEA:17105		molecular_function											owl:Class	
GO:0043353	biolink:NamedThing	enucleate erythrocyte differentiation	The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus.	got7fsn_ti	enucleate red blood cell differentiation|enucleate RBC differentiation													biological_process											owl:Class	
GO:0030218	biolink:NamedThing	erythrocyte differentiation	The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.	got7fsn_ti	erythropoiesis|red blood cell differentiation|erythrocyte cell differentiation|RBC differentiation											Wikipedia:Erythropoiesis		biological_process											owl:Class	
GO:0098618	biolink:NamedThing	selenomethionine-tRNA ligase activity	Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met).	got7fsn_ti												Reactome:R-HSA-2408546		molecular_function											owl:Class	
GO:0021999	biolink:NamedThing	neural plate anterior/posterior regionalization	The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.	got7fsn_ti	neural plate anterior/posterior pattern formation													biological_process											owl:Class	
GO:0034880	biolink:NamedThing	citrazinate dehydrogenase activity	Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1339		molecular_function											owl:Class	
GO:0016721	biolink:NamedThing	oxidoreductase activity, acting on superoxide radicals as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor.	got7fsn_ti												EC:1.15.-.-		molecular_function											owl:Class	
GO:0002447	biolink:NamedThing	eosinophil mediated immunity	Any process involved in the carrying out of an immune response by an eosinophil.	got7fsn_ti														biological_process											owl:Class	
GO:0120086	biolink:NamedThing	(3S)-(+)-asterisca-2(9),6-diene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene.	got7fsn_ti	asterisca-2(9),6-diene synthase activity						krc	2017-08-02T14:55:38Z						molecular_function											owl:Class	
GO:0004972	biolink:NamedThing	NMDA glutamate receptor activity	An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized.  Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages.	got7fsn_ti	N-methyl-D-aspartate selective glutamate receptor activity|NMDA receptor				The name of this receptor comes from its selective activation by N-methyl-D-aspartate (NMDA). Note that this term represents an activity and not a gene product.							Wikipedia:NMDA_receptor		molecular_function											owl:Class	
GO:0004970	biolink:NamedThing	ionotropic glutamate receptor activity	Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.	got7fsn_ti					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'glutamate-gated ion channel activity ; GO:0005234' and 'cation channel activity ; GO:0005261'.									molecular_function											owl:Class	
GO:0014822	biolink:NamedThing	detection of wounding	The series of events by which an injury stimulus is received and converted into a molecular signal.	got7fsn_ti	detection of injury													biological_process											owl:Class	
GO:2000935	biolink:NamedThing	positive regulation of cellotriose metabolic process	Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process.	got7fsn_ti	positive regulation of cellotriose metabolism						tt	2011-08-01T12:44:24Z						biological_process											owl:Class	
GO:0061714	biolink:NamedThing	folic acid receptor activity	Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis.	got7fsn_ti	folate receptor activity						dph	2015-06-23T13:36:07Z						molecular_function											owl:Class	
GO:0038024	biolink:NamedThing	cargo receptor activity	Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.	got7fsn_ti	endocytic receptor activity|receptor activity|receptor activity involved in receptor-mediated endocytosis|transport receptor activity				Notes: (1) this term and its child terms are intended for receptors that bind to and internalize molecules by receptor-mediated endocytosis. For receptors that are coupled to a signal transduction pathway, consider instead the term 'signaling receptor activity ; GO:0038023' and its children. (2) Cargo receptors transport substances by vesicular transport, not by transmembrane transport.  For transmembrane transporters, consider instead the term 'transmembrane transporter activity ; GO:0022857.		bf	2011-08-01T02:50:45Z				Reactome:R-HSA-3000122|Reactome:R-HSA-350168		molecular_function											owl:Class	
GO:0006589	biolink:NamedThing	octopamine biosynthetic process	The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.	got7fsn_ti	octopamine formation|octopamine synthesis|octopamine biosynthesis|octopamine anabolism													biological_process											owl:Class	
GO:0042136	biolink:NamedThing	neurotransmitter biosynthetic process	The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.	got7fsn_ti	neurotransmitter synthesis|neurotransmitter biosynthetic process and storage|neurotransmitter anabolism|neurotransmitter formation|neurotransmitter biosynthesis|neurotransmitter biosynthesis and storage													biological_process											owl:Class	
GO:0045760	biolink:NamedThing	positive regulation of action potential	Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti	activation of action potential|up regulation of action potential|up-regulation of action potential|stimulation of action potential|upregulation of action potential													biological_process											owl:Class	
GO:0062101	biolink:NamedThing	peptidyl-aspartic acid 3-dioxygenase activity	Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2.	got7fsn_ti	peptide-aspartate beta-dioxygenase activity|aspartyl/asparaginyl beta-hydroxylase activity|aspartylpeptide beta-dioxygenase activity|aspartate beta-hydroxylase activity|peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity	https://github.com/geneontology/go-ontology/issues/17842					dph	2018-12-06T14:01:15Z			GO:0004597	RHEA:11508|MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN|EC:1.14.11.16		molecular_function											owl:Class	
GO:0045682	biolink:NamedThing	regulation of epidermis development	Any process that modulates the frequency, rate or extent of epidermis development.	got7fsn_ti	regulation of epidermal development|regulation of hypodermis development													biological_process											owl:Class	
GO:0072164	biolink:NamedThing	mesonephric tubule development	The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.	got7fsn_ti							mah	2010-02-26T01:45:58Z						biological_process											owl:Class	
GO:1902107	biolink:NamedThing	positive regulation of leukocyte differentiation	Any process that activates or increases the frequency, rate or extent of leukocyte differentiation.	got7fsn_ti	up regulation of leucocyte differentiation|upregulation of leukocyte differentiation|positive regulation of leucocyte differentiation|up regulation of immune cell differentiation|up regulation of leukocyte differentiation|activation of leucocyte differentiation|upregulation of immune cell differentiation|up-regulation of leukocyte differentiation|activation of immune cell differentiation|up-regulation of leucocyte differentiation|up-regulation of immune cell differentiation|upregulation of leucocyte differentiation|activation of leukocyte differentiation|positive regulation of immune cell differentiation						pr	2013-05-02T17:32:52Z						biological_process											owl:Class	
GO:0006807	biolink:NamedThing	nitrogen compound metabolic process	The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.	got7fsn_ti	nitrogen compound metabolism													biological_process											owl:Class	
GO:0002431	biolink:NamedThing	Fc receptor mediated stimulatory signaling pathway	A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.	got7fsn_ti	Fc receptor mediated stimulatory signalling pathway|Fc-receptor mediated stimulatory signaling pathway													biological_process											owl:Class	
GO:0031710	biolink:NamedThing	neuromedin B receptor binding	Binding to a neuromedin B receptor.	got7fsn_ti	neuromedin B receptor ligand													molecular_function											owl:Class	
GO:0002237	biolink:NamedThing	response to molecule of bacterial origin	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.	got7fsn_ti	response to bacterium associated molecule|response to bacterial associated molecule|response to bacteria associated molecule													biological_process											owl:Class	
GO:0031158	biolink:NamedThing	negative regulation of aggregate size involved in sorocarp development	Any process that decreases the size of the aggregate formed during sorocarp formation.	got7fsn_ti	down regulation of aggregate size|down-regulation of aggregate size|inhibition of aggregate size|downregulation of aggregate size													biological_process											owl:Class	
GO:1905332	biolink:NamedThing	positive regulation of morphogenesis of an epithelium	Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium.	got7fsn_ti	activation of epithelium morphogenesis|up-regulation of epithelium morphogenesis|up regulation of epithelium morphogenesis|up regulation of morphogenesis of an epithelium|positive regulation of epithelium morphogenesis|activation of morphogenesis of an epithelium|up-regulation of morphogenesis of an epithelium|upregulation of epithelium morphogenesis|upregulation of morphogenesis of an epithelium				An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-07-22T07:14:05Z						biological_process											owl:Class	
GO:0002773	biolink:NamedThing	B cell inhibitory signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response.	got7fsn_ti	B cell inhibitory signalling pathway|B lymphocyte inhibitory signaling pathwayBT-lymphocyte inhibitory signaling pathway|B-cell inhibitory signaling pathway													biological_process											owl:Class	
GO:0043643	biolink:NamedThing	tetracycline metabolic process	The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).	got7fsn_ti	tetracyclin metabolic process|tetracycline metabolism|tetracyclin metabolism													biological_process											owl:Class	
GO:0004077	biolink:NamedThing	biotin-[acetyl-CoA-carboxylase] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)).	got7fsn_ti	biotin holoenzyme synthetase activity|biotin:apocarboxylase ligase activity|biotin-acetyl coenzyme A carboxylase synthetase activity|biotin-acetyl-CoA carboxylase synthetase|HCS|acetyl-CoA carboxylase biotin holoenzyme synthetase activity|acetyl coenzyme A holocarboxylase synthetase activity|acetyl CoA holocarboxylase synthetase activity|biotin--[acetyl-CoA carboxylase] synthetase activity|biotin-acetyl-CoA-carboxylase ligase activity|biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin--protein ligase activity											RHEA:11756|MetaCyc:BIOTINLIG-RXN|EC:6.3.4.15		molecular_function											owl:Class	
GO:0000951	biolink:NamedThing	methionine catabolic process to 3-methylthiopropanol	The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.	got7fsn_ti														biological_process											owl:Class	
GO:0005128	biolink:NamedThing	erythropoietin receptor binding	Binding to an erythropoietin receptor.	got7fsn_ti	erythropoietin receptor ligand|erythropoietin													molecular_function											owl:Class	
GO:0140635	biolink:NamedThing	neutrophil dispersal	The movement of a neutrophil away from the site of wound or infection following its initial migration to the site.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21081					pg	2021-04-13T07:06:25Z						biological_process											owl:Class	
GO:1990266	biolink:NamedThing	neutrophil migration	The movement of a neutrophil within or between different tissues and organs of the body.	got7fsn_ti							sl	2014-01-10T00:17:47Z						biological_process											owl:Class	
GO:0030847	biolink:NamedThing	termination of RNA polymerase II transcription, exosome-dependent	The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.	got7fsn_ti	transcription termination from Pol II promoter, RNA polymerase(A)-independent|transcription termination from Pol II promoter, poly(A)-independent|termination of RNA polymerase II transcription, poly(A)-independent													biological_process											owl:Class	
GO:0006369	biolink:NamedThing	termination of RNA polymerase II transcription	The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.	got7fsn_ti	transcription termination from Pol II promoter|RNA polymerase II transcription termination factor activity|transcription termination from RNA polymerase II promoter|RNA polymerase II transcription termination|RNA 3'-end formation by RNA polymerase II										GO:0019224			biological_process											owl:Class	
GO:0071711	biolink:NamedThing	basement membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.	got7fsn_ti	basement membrane organisation				Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer.		mah	2010-03-10T11:57:10Z						biological_process											owl:Class	
GO:0016476	biolink:NamedThing	regulation of embryonic cell shape	Any process that modulates the surface configuration of an embryonic cell.	got7fsn_ti	shape changes of embryonic cells													biological_process											owl:Class	
GO:0016545	biolink:NamedThing	male courtship behavior, veined wing vibration	The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster.	got7fsn_ti	male courtship behavior, wing vibration|male courtship behaviour, wing vibration|male courtship behaviour, veined wing vibration													biological_process											owl:Class	
GO:0048065	biolink:NamedThing	male courtship behavior, veined wing extension	The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	male courtship behaviour, wing extension|male courtship behavior, wing extension|male courtship behaviour, veined wing extension													biological_process											owl:Class	
GO:0043916	biolink:NamedThing	DNA-7-methylguanine glycosylase activity	Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site.	got7fsn_ti												MetaCyc:3.2.2.21-RXN|EC:3.2.2.21		molecular_function											owl:Class	
GO:0003905	biolink:NamedThing	alkylbase DNA N-glycosylase activity	Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.	got7fsn_ti	DNA-3-methyladenine glycosidase II activity|deoxyribonucleate 3-methyladenine glycosidase II|DNA glycosidase II activity|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|DNA-3-methyladenine glycosylase II|alkylbase DNA glycosidase activity|3-methyladenine DNA glycosylase II|AlkA										GO:0004036	EC:3.2.2.21|MetaCyc:3.2.2.21-RXN		molecular_function											owl:Class	
GO:0004521	biolink:NamedThing	endoribonuclease activity	Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.	got7fsn_ti	endonuclease G activity											Reactome:R-HSA-425923|Reactome:R-HSA-6791223|Reactome:R-HSA-9023909|Reactome:R-HSA-5601910|Reactome:R-HSA-9023912|Reactome:R-HSA-5601887|Reactome:R-HSA-6814555|Reactome:R-HSA-9009936|Reactome:R-HSA-426520|Reactome:R-HSA-927836|Reactome:R-HSA-9009941		molecular_function											owl:Class	
GO:0102014	biolink:NamedThing	beta-D-galactose-importing ATPase activity	Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O <=> ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+.	got7fsn_ti												MetaCyc:ABC-18-RXN|RHEA:30011		molecular_function											owl:Class	
GO:0015407	biolink:NamedThing	ABC-type monosaccharide transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported.	got7fsn_ti	ATPase-coupled monosaccharide transmembrane transporter activity|monosaccharide ABC transporter|ATP-dependent monosaccharide transmembrane transporter activity|monosaccharide-importing ATPase activity|monosaccharide-transporting ATPase activity	https://github.com/geneontology/go-ontology/issues/17289										MetaCyc:3.6.3.17-RXN|EC:7.5.2.-		molecular_function											owl:Class	
GO:0052167	biolink:NamedThing	modulation by symbiont of host innate immune response	Any process in which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host innate immunity|modulation of host innate immune response|modulation by organism of innate immune response in other organism involved in symbiotic interaction										GO:0052306			biological_process											owl:Class	
GO:0006431	biolink:NamedThing	methionyl-tRNA aminoacylation	The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0003234	biolink:NamedThing	bulbus arteriosus formation	The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.	got7fsn_ti							dph	2009-10-13T11:10:02Z						biological_process											owl:Class	
GO:0039714	biolink:NamedThing	cytoplasmic viral factory	A viral factory located in the cytoplasm of a host cell.	got7fsn_ti							bf	2013-12-19T15:16:15Z						cellular_component											owl:Class	
GO:0039713	biolink:NamedThing	viral factory	An intracellular compartment in a host cell which increases the efficiency of viral replication, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments.	got7fsn_ti	virus factory						bf	2013-12-19T14:53:47Z				VZ:1951		cellular_component											owl:Class	
GO:0002084	biolink:NamedThing	protein depalmitoylation	The removal of palymitoyl groups from a lipoprotein.	got7fsn_ti														biological_process											owl:Class	
GO:0098734	biolink:NamedThing	macromolecule depalmitoylation	The removal of palymitoyl groups from a macromolecule.	got7fsn_ti														biological_process											owl:Class	
GO:0032922	biolink:NamedThing	circadian regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.	got7fsn_ti	diurnal variation of gene expression|circadian regulation of protein expression|diurnal variation of protein expression													biological_process											owl:Class	
GO:0062205	biolink:NamedThing	miltiradiene synthase activity	Catalysis of the reaction: (+)-copalyl diphosphate = diphosphate + miltiradiene.	got7fsn_ti	multiradiene synthase activity						dph	2020-01-03T14:05:49Z			GO:0102353	MetaCyc:RXN-13338|EC:4.2.3.131|RHEA:33983		molecular_function											owl:Class	
GO:0070111	biolink:NamedThing	organellar chromatophore	A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora.	got7fsn_ti	Paulinella-type chromatophore													cellular_component											owl:Class	
GO:0043660	biolink:NamedThing	bacteroid-containing symbiosome	A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants.	got7fsn_ti														cellular_component											owl:Class	
GO:0047519	biolink:NamedThing	quinate dehydrogenase (quinone) activity	Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol.	got7fsn_ti	quinate:quinone 3-oxidoreductase activity|NAD(P)-independent quinate dehydrogenase activity|quinate:pyrroloquinoline-quinone 5-oxidoreductase activity											MetaCyc:1.1.99.25-RXN|RHEA:23672|EC:1.1.5.8|KEGG_REACTION:R01873		molecular_function											owl:Class	
GO:0010227	biolink:NamedThing	floral organ abscission	The controlled shedding of floral organs.	got7fsn_ti														biological_process											owl:Class	
GO:0035161	biolink:NamedThing	imaginal disc lineage restriction	Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0038192	biolink:NamedThing	gastric inhibitory peptide signaling pathway	The series of molecular signals generated as a consequence of a gastric inhibitory peptide (GIP) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	gastric inhibitory polypeptide receptor signaling pathway|glucose-dependent insulinotropic polypeptide signaling|GIP signaling						bf	2013-09-02T15:57:49Z						biological_process											owl:Class	
GO:0043779	biolink:NamedThing	cobalt-precorrin-5A acetaldehyde-lyase activity	Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde.	got7fsn_ti	cobalt-precorrin 5A acetaldehyde-lyase activity											MetaCyc:RXN-8763|RHEA:26281		molecular_function											owl:Class	
GO:0016829	biolink:NamedThing	lyase activity	Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.	got7fsn_ti	other lyase activity											EC:4.-.-.-|Reactome:R-HSA-5696408|Reactome:R-HSA-6782895		molecular_function											owl:Class	
GO:0090434	biolink:NamedThing	oleoyl-CoA ligase activity	Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA.	got7fsn_ti	oleoyl-CoA synthetase activity						tb	2012-07-25T03:31:31Z						molecular_function											owl:Class	
GO:0019836	biolink:NamedThing	hemolysis by symbiont of host erythrocytes	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	hemolysis by symbiont of host red blood cells|hemolysin activity|hemolysis by symbiont of host RBCs|regulation of cytolysis of host cells by symbiont|haemolysis in host|pathogenesis													biological_process											owl:Class	
GO:0052331	biolink:NamedThing	hemolysis in other organism involved in symbiotic interaction	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another, where two organisms are in a symbiotic interaction.	got7fsn_ti	hemolysis of cells in other organism during symbiotic interaction|hemolysis by organism of RBCs in other organism during symbiotic interaction|haemolysis in other organism involved in symbiotic interaction|hemolysis by organism of red blood cells in other organism during symbiotic interaction|hemolysis by organism of erythrocytes in other organism during symbiotic interaction|hemolysis of cells in other organism involved in symbiotic interaction|hemolysin activity													biological_process											owl:Class	
GO:0090735	biolink:NamedThing	DNA repair complex assembly	The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex.	got7fsn_ti							tb	2017-02-06T16:42:27Z						biological_process											owl:Class	
GO:0010065	biolink:NamedThing	primary meristem tissue development	The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium.	got7fsn_ti	primary meristem histogenesis													biological_process											owl:Class	
GO:0048508	biolink:NamedThing	embryonic meristem development	The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0021935	biolink:NamedThing	cerebellar granule cell precursor tangential migration	The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium.	got7fsn_ti														biological_process											owl:Class	
GO:1990392	biolink:NamedThing	EFF-1 complex	A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer.	got7fsn_ti					An example of this is eff-1 in C. elegans (G5ECA1) in PMID:24725407 (inferred from direct assay).		bhm	2014-06-04T14:45:02Z						cellular_component											owl:Class	
GO:0070324	biolink:NamedThing	thyroid hormone binding	Binding to thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.	got7fsn_ti	triiodothyronine binding|thyroxine binding													molecular_function											owl:Class	
GO:0002434	biolink:NamedThing	immune complex clearance	A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution.	got7fsn_ti														biological_process											owl:Class	
GO:0031556	biolink:NamedThing	transcriptional attenuation by ribosome	A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.	got7fsn_ti	ribosome-mediated transcriptional attenuation													biological_process											owl:Class	
GO:0031555	biolink:NamedThing	transcriptional attenuation	Regulation of transcription through variation in where transcription termination occurs.	got7fsn_ti												Wikipedia:Attenuator_(genetics)		biological_process											owl:Class	
GO:0005614	biolink:NamedThing	interstitial matrix	A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.	got7fsn_ti														cellular_component											owl:Class	
GO:0047718	biolink:NamedThing	indanol dehydrogenase activity	Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+.	got7fsn_ti	indan-1-ol:NAD(P)+ 1-oxidoreductase activity											EC:1.1.1.112|MetaCyc:INDANOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0004126	biolink:NamedThing	cytidine deaminase activity	Catalysis of the reaction: cytidine + H2O = uridine + NH3.	got7fsn_ti	cytosine nucleoside deaminase activity|cytidine aminohydrolase activity											MetaCyc:CYTIDEAM2-RXN|RHEA:16069|Reactome:R-HSA-83677|Reactome:R-HSA-73608|EC:3.5.4.5		molecular_function											owl:Class	
GO:0004897	biolink:NamedThing	ciliary neurotrophic factor receptor activity	Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	CNTF receptor activity|gp130													molecular_function											owl:Class	
GO:0033197	biolink:NamedThing	response to vitamin E	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.	got7fsn_ti	response to DL-alpha-tocopheryl acetate|response to O-Acetyl-alpha-tocopherol|response to DL-alpha-tocopherol acetate													biological_process											owl:Class	
GO:1901700	biolink:NamedThing	response to oxygen-containing compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.	got7fsn_ti	response to oxygen molecular entity						pr	2012-12-13T15:11:37Z						biological_process											owl:Class	
GO:0072527	biolink:NamedThing	pyrimidine-containing compound metabolic process	The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.	got7fsn_ti	pyrimidine and derivative metabolic process|pyrimidine-containing compound metabolism						mah	2011-01-04T03:27:19Z						biological_process											owl:Class	
GO:0009918	biolink:NamedThing	sterol delta7 reductase activity	Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol.	got7fsn_ti	sterol delta-7 reductase activity											MetaCyc:RXN-707		molecular_function											owl:Class	
GO:0001018	biolink:NamedThing	mitochondrial promoter sequence-specific DNA binding	Binding to a DNA region that controls the transcription of the mitochondrial DNA.	got7fsn_ti	LSPs binding|mitochondrial heavy strand promoter sense binding|LSP non-coding strand binding|mitochondrial proximal promoter sequence-specific DNA binding|mitochondrial RNA polymerase regulatory region DNA binding|mitochondrial RNA polymerase regulatory region sequence-specific DNA binding|LSPas binding|mitochondrial light strand promoter sense binding|HSPas binding|LSP coding strand binding|HSP coding strand binding|mitochondrial RNA polymerase core promoter sequence-specific DNA binding|mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding|mitochondrial light strand promoter anti-sense binding|HSPs binding|mitochondrial heavy strand promoter anti-sense binding|HSP non-coding strand binding						krc	2010-08-25T04:11:49Z			GO:0070362|GO:0001045|GO:0000997|GO:0070364|GO:0070363|GO:0070361|GO:0001044			molecular_function											owl:Class	
GO:0000976	biolink:NamedThing	transcription cis-regulatory region binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.	got7fsn_ti	transcription regulatory region sequence-specific DNA binding|regulatory region DNA binding|transcription regulatory region DNA binding	https://github.com/geneontology/go-ontology/issues/19312|https://github.com/geneontology/go-ontology/issues/20791			Note that this term is meant to also capture non-specific binding to regulatory regions. Also, to minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2010-08-10T11:00:02Z			GO:0000975|GO:0044212			molecular_function											owl:Class	
GO:0000422	biolink:NamedThing	autophagy of mitochondrion	The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.	got7fsn_ti	mitochondrion autophagy|mitophagy											Wikipedia:Autophagy_(cellular)#Selective_autophagy|Wikipedia:Mitophagy		biological_process											owl:Class	
GO:0006914	biolink:NamedThing	autophagy	The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.	got7fsn_ti											GO:0016238	Wikipedia:Autophagy_(cellular)		biological_process											owl:Class	
GO:0061953	biolink:NamedThing	mRNA (adenine-N1-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA.	got7fsn_ti							dph	2017-11-08T13:26:35Z						molecular_function											owl:Class	
GO:0008298	biolink:NamedThing	intracellular mRNA localization	Any process in which mRNA is transported to, or maintained in, a specific location within the cell.	got7fsn_ti	mRNA positioning, intracellular|intracellular mRNA positioning|establishment and maintenance of intracellular RNA localization|mRNA localization, intracellular|intracellular mRNA localisation													biological_process											owl:Class	
GO:0038175	biolink:NamedThing	negative regulation of SREBP signaling pathway in response to increased oxygen levels	Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels.	got7fsn_ti	negative regulation of SREBP-mediated signaling pathway in presence of oxygen|negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels						bf	2012-07-20T01:28:59Z						biological_process											owl:Class	
GO:2000639	biolink:NamedThing	negative regulation of SREBP signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway.	got7fsn_ti	negative regulation of SREBP-mediated signalling pathway|negative regulation of SREBP-mediated signaling pathway						vk	2011-04-20T02:46:02Z						biological_process											owl:Class	
GO:0010222	biolink:NamedThing	stem vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the stem of vascular plants.	got7fsn_ti														biological_process											owl:Class	
GO:1990664	biolink:NamedThing	Nkx-2.5 complex	A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes.	got7fsn_ti	NKX2.5 complex|Nkx-2.5 homodimer complex|NKX.2-5 homodimer complex|NKX2E homodimer complex				An example of this is Nkx-2.5 in human (UniProt symbol P52952) in PMID:22849347 (inferred from direct assay).		ame	2015-02-27T12:22:06Z						cellular_component											owl:Class	
GO:0044846	biolink:NamedThing	negative regulation by symbiont of indole acetic acid levels in host	Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of IAA levels in host|negative regulation by symbiont of auxin levels in host						jl	2014-05-13T11:08:04Z						biological_process											owl:Class	
GO:0044032	biolink:NamedThing	modulation by symbiont of indole acetic acid levels in host	The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of IAA levels in host|modulation by symbiont of auxin levels in host				Note that this term is intended for use in annotation of symbiont gene products. For host gene products that regulate indole acetic acid levels in the host, consider annotating to 'auxin homeostasis ; GO:0010252'.									biological_process											owl:Class	
GO:0046600	biolink:NamedThing	negative regulation of centriole replication	Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication.	got7fsn_ti	down-regulation of centriole replication|inhibition of centriole replication|downregulation of centriole replication|down regulation of centriole replication													biological_process											owl:Class	
GO:0046934	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).	got7fsn_ti	type I phosphoinositide 3-kinase activity|phosphatidylinositol 3-kinase activity, class I|phosphatidylinositol 3-kinase, class I, catalyst activity|phosphatidylinositol 3-kinase activity, class II|ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity											Reactome:R-HSA-2029271|Reactome:R-HSA-8852019|Reactome:R-HSA-9672177|Reactome:R-HSA-5654701|Reactome:R-HSA-5654692|Reactome:R-HSA-202365|KEGG_REACTION:R04545|Reactome:R-HSA-9665407|Reactome:R-HSA-2730870|Reactome:R-HSA-1250462|Reactome:R-HSA-437162|Reactome:R-HSA-392300|Reactome:R-HSA-2424480|Reactome:R-HSA-5654709|Reactome:R-HSA-5655289|Reactome:R-HSA-5654717|Reactome:R-HSA-5655290|MetaCyc:2.7.1.153-RXN|Reactome:R-HSA-177939|Reactome:R-HSA-1839107|Reactome:R-HSA-1226014|Reactome:R-HSA-9664940|Reactome:R-HSA-1306957|Reactome:R-HSA-5654714|Reactome:R-HSA-1839091|Reactome:R-HSA-5637801|Reactome:R-HSA-186800|Reactome:R-HSA-2316434|Reactome:R-HSA-5655235|Reactome:R-HSA-389158|Reactome:R-HSA-9021627|RHEA:21292|Reactome:R-HSA-5654690|Reactome:R-HSA-1250370|Reactome:R-HSA-5654697|Reactome:R-HSA-5654705|Reactome:R-HSA-198266|Reactome:R-HSA-9603445|Reactome:R-HSA-2076220|Reactome:R-HSA-1676048|Reactome:R-HSA-5655323|Reactome:R-HSA-5218819|Reactome:R-HSA-9672162|Reactome:R-HSA-1306979|Reactome:R-HSA-2394007|Reactome:R-HSA-9664664|EC:2.7.1.153|Reactome:R-HSA-8853323		molecular_function											owl:Class	
GO:0051606	biolink:NamedThing	detection of stimulus	The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.	got7fsn_ti	stimulus sensing|perception of stimulus|stimulus detection													biological_process											owl:Class	
GO:0120107	biolink:NamedThing	bacterial-type flagellum rotor complex	The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation.	got7fsn_ti							krc	2017-10-17T20:54:45Z						cellular_component											owl:Class	
GO:0050495	biolink:NamedThing	peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine.	got7fsn_ti	peptidyl-glycyl-phosphatidylethanolamine anabolism from peptidyl-glycine|peptidyl-glycyl-phosphatidylethanolamine synthesis from peptidyl-glycine|peptidyl-glycyl-phosphatidylethanolamine formation from peptidyl-glycine											RESID:AA0346		biological_process											owl:Class	
GO:0005934	biolink:NamedThing	cellular bud tip	The end of a cellular bud distal to the site of attachment to the mother cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0005618	biolink:NamedThing	cell wall	The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21669			Not to be used for manual annotation.  Please choose a more specific term: for bacteria, annotate to GO:0009274; peptidoglycan-based cell wall, for  plants: annotate to GO:0009505 ; plant-type cell wall, for fungi: GO:0009277 ; fungal-type cell wall, and for archae, use GO:0030115 S-layer (see PMID:31214995).							Wikipedia:Cell_wall		cellular_component											owl:Class	
GO:0016893	biolink:NamedThing	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.	got7fsn_ti	endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters|5'-endonuclease activity				Note that this activity can catalyze cleavage of DNA or RNA.							EC:3.1.30.-		molecular_function											owl:Class	
GO:0004519	biolink:NamedThing	endonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.	got7fsn_ti												Reactome:R-HSA-5358518|Reactome:R-HSA-5358512|Reactome:R-HSA-72180|Reactome:R-HSA-5693533|Reactome:R-HSA-5690990		molecular_function											owl:Class	
GO:0071700	biolink:NamedThing	olfactory placode maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.	got7fsn_ti							mah	2010-03-02T01:10:54Z						biological_process											owl:Class	
GO:0002491	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class II	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0001119	biolink:NamedThing	protein-DNA-RNA complex remodeling	The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex.	got7fsn_ti							krc	2010-12-03T04:15:52Z						biological_process											owl:Class	
GO:0034367	biolink:NamedThing	protein-containing complex remodeling	The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.	got7fsn_ti	macromolecular complex remodeling													biological_process											owl:Class	
GO:0004622	biolink:NamedThing	lysophospholipase activity	Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.	got7fsn_ti	lysophopholipase L2|lysophospholipase A1|lysophosphatidylcholine hydrolase activity|lecithinase B activity|lysophosphatidase activity|lysolecithinase activity|phosphatidase B|lecitholipase activity|2-lysophosphatidylcholine acylhydrolase activity|phospholipase B activity										GO:0045126	Reactome:R-HSA-1482571|Reactome:R-HSA-8847912|Reactome:R-HSA-1482685|MetaCyc:LYSOPHOSPHOLIPASE-RXN|Reactome:R-HSA-1482629|Reactome:R-HSA-1482696|RHEA:15177|Reactome:R-HSA-6814254|Reactome:R-HSA-6814766|Reactome:R-HSA-6814778|EC:3.1.1.5|Reactome:R-HSA-1482612|Reactome:R-HSA-1482545		molecular_function											owl:Class	
GO:0034386	biolink:NamedThing	4-aminobutyrate:2-oxoglutarate transaminase activity	Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.	got7fsn_ti	GABA-2-oxoglutarate transaminase activity|GABA-oxoglutarate aminotransferase activity|GABA-alpha-ketoglutarate transaminase activity|gamma-aminobutyrate:alpha-oxoglutarate aminotransferase activity|GABA-alpha-oxoglutarate aminotransferase activity|gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase activity|4-aminobutyrate-2-ketoglutarate aminotransferase activity|GABA-2-oxoglutarate aminotransferase activity|4-aminobutyrate-2-oxoglutarate transaminase activity|GABA-alpha-ketoglutarate aminotransferase activity|gamma-aminobutyrate-alpha-ketoglutarate aminotransferase activity|GABA-alpha-ketoglutaric acid transaminase activity|4-aminobutyric acid 2-ketoglutaric acid aminotransferase activity|4-aminobutyrate-2-oxoglutarate aminotransferase activity|gamma-aminobutyric acid-2-oxoglutarate transaminase activity|gamma-aminobutyric acid-alpha-ketoglutarate transaminase activity|4-aminobutanoate:2-oxoglutarate aminotransferase activity|GABA-oxoglutarate transaminase activity|gamma-aminobutyrate-alpha-ketoglutarate transaminase activity											MetaCyc:GABATRANSAM-RXN|EC:2.6.1.19		molecular_function											owl:Class	
GO:0031472	biolink:NamedThing	propanediol degradation polyhedral organelle	An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase.	got7fsn_ti														cellular_component											owl:Class	
GO:0031469	biolink:NamedThing	polyhedral organelle	An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.	got7fsn_ti	BAC|bacterial microcompartment	https://github.com/geneontology/go-ontology/issues/16852												cellular_component											owl:Class	
GO:0032120	biolink:NamedThing	ascospore-type prospore membrane formation	The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.	got7fsn_ti	FSM biosynthesis|forespore membrane formation|FSM formation|prospore membrane biogenesis|ascospore-type prospore membrane assembly|forespore membrane biosynthesis|FSM assembly	https://github.com/geneontology/go-ontology/issues/14712									GO:0099097			biological_process											owl:Class	
GO:0048000	biolink:NamedThing	isoflavone 3'-hydroxylase activity	Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O.	got7fsn_ti	formononetin,NADPH:oxygen oxidoreductase (3'-hydroxylating)|isoflavone 3'-monooxygenase activity											EC:1.14.14.88|RHEA:22960|MetaCyc:RXN-3762		molecular_function											owl:Class	
GO:0018699	biolink:NamedThing	1,1,1-trichloroethane reductive dehalogenase activity	Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl.	got7fsn_ti												EC:1.97.1.-|UM-BBD_reactionID:r1007		molecular_function											owl:Class	
GO:0051214	biolink:NamedThing	RNAi-mediated antiviral immunity against RNA virus	Gene silencing induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing. In plants, DCL4 is the primary Dicer to detect RNA viruses.	got7fsn_ti	RNA virus-induced gene silencing|RNA VIGS|RNA virus induced gene silencing	https://github.com/geneontology/go-ontology/issues/19958												biological_process											owl:Class	
GO:0009616	biolink:NamedThing	RNAi-mediated antiviral immune response	RNA-mediated post-transcriptional gene silencing mechanism that protects against foreign organism invasion by restricting viral replication and dissemination.	got7fsn_ti	RNAi-mediated antiviral immunity|viral triggering of virus induced gene silencing|virus-induced gene silencing|VIGS|virus induced gene silencing|viral gene silencing in virus induced gene silencing	https://github.com/geneontology/go-ontology/issues/19958			Virus induced gene silencing (VIGS) is used as a technique to control plant gene expression; when used in that context, this does not represent a normal biological process and is outside the scope of GO.						GO:0060150|GO:0060145			biological_process											owl:Class	
GO:0001563	biolink:NamedThing	detection of protozoan	The series of events in which a stimulus from a protozoan is received and converted into a molecular signal.	got7fsn_ti	detection of protozoa|perception of protozoa|detection of protozoon													biological_process											owl:Class	
GO:0005853	biolink:NamedThing	eukaryotic translation elongation factor 1 complex	A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.	got7fsn_ti														cellular_component											owl:Class	
GO:0044072	biolink:NamedThing	negative regulation by symbiont of host cell cycle	The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery.	got7fsn_ti														biological_process											owl:Class	
GO:0044071	biolink:NamedThing	modulation by symbiont of host cell cycle	The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery.	got7fsn_ti	regulation by symbiont of host cell cycle|modulation of host cell cycle by symbiont|modification by symbiont of host cell cycle													biological_process											owl:Class	
GO:0015057	biolink:NamedThing	thrombin-activated receptor activity	A G protein-coupled receptor activity that is activated by cleavage by thrombin, which exposes a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.	got7fsn_ti	thrombin receptor activity, G-protein coupled|thrombin receptor activity										GO:0010655			molecular_function											owl:Class	
GO:0016232	biolink:NamedThing	HNK-1 sulfotransferase activity	Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R).	got7fsn_ti	HNK-1 sulphotransferase activity											Reactome:R-HSA-6786048		molecular_function											owl:Class	
GO:0031159	biolink:NamedThing	positive regulation of aggregate size involved in sorocarp development	Any process that increases the size of the aggregate formed during sorocarp formation.	got7fsn_ti	up-regulation of aggregate size|up regulation of aggregate size|activation of aggregate size|stimulation of aggregate size|upregulation of aggregate size													biological_process											owl:Class	
GO:0071920	biolink:NamedThing	cleavage body	A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.	got7fsn_ti							mah	2010-09-28T10:35:05Z						cellular_component											owl:Class	
GO:1990258	biolink:NamedThing	histone glutamine methylation	The modification of a histone by addition of a methyl group to an glutamine residue.	got7fsn_ti							sp	2014-01-02T15:08:02Z						biological_process											owl:Class	
GO:0071220	biolink:NamedThing	cellular response to bacterial lipoprotein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.	got7fsn_ti							mah	2009-12-03T01:26:36Z						biological_process											owl:Class	
GO:0052605	biolink:NamedThing	gamma-tocopherol cyclase activity	Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol.	got7fsn_ti												RHEA:37983|MetaCyc:RXN-2543|KEGG_REACTION:R07502		molecular_function											owl:Class	
GO:0140423	biolink:NamedThing	effector-mediated suppression of host pattern-triggered immunity signaling	A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants.	got7fsn_ti	effector-mediated suppression of PTI signalling|effector-mediated suppression of pattern-triggered immunity signaling|effector-mediated suppression of host PRR signalling|effector-mediated suppression of host pattern recognition receptor signaling|effector-mediated suppression of host PRR signaling	https://github.com/geneontology/go-ontology/issues/18683					pg	2020-02-03T09:50:33Z						biological_process											owl:Class	
GO:0052034	biolink:NamedThing	effector-mediated suppression of host pattern-triggered immunity	A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	suppression of pathogen-associated molecular pattern-induced host innate immunity|negative regulation by organism of pathogen-associated molecular pattern-induced innate immune response of other organism involved in symbiotic interaction|down-regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression of general elicitor-induced host innate immunity|suppression of MAMP induced host innate immunity|suppression of PAMP induced host innate immunity|suppression of PAMP-induced host innate immunity|negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immunity|downregulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression by symbiont of microbe-associated molecular pattern-induced host innate immune response|negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immune response|suppression of MAMP-induced host innate immunity|down regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression of general elicitor induced host innate immunity|inhibition by symbiont of pathogen-associated molecular pattern-induced host innate immunity	https://github.com/geneontology/go-ontology/issues/21161									GO:0052258			biological_process											owl:Class	
GO:0005042	biolink:NamedThing	netrin receptor activity	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0000709	biolink:NamedThing	meiotic joint molecule formation	The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0061533	biolink:NamedThing	norepinephrine secretion, neurotransmission	The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.	got7fsn_ti	noradrenaline secretion, neurotransmission						dph	2013-06-21T16:05:08Z						biological_process											owl:Class	
GO:0048243	biolink:NamedThing	norepinephrine secretion	The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.	got7fsn_ti	noradrenaline secretion													biological_process											owl:Class	
GO:0038139	biolink:NamedThing	ERBB4-EGFR complex	A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1).	got7fsn_ti	EGFR-ERBB4 complex|ERBB4:EGFR heterodimer						bf	2012-03-30T01:59:41Z						cellular_component											owl:Class	
GO:0005584	biolink:NamedThing	collagen type I trimer	A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils.	got7fsn_ti												Wikipedia:Collagen_type_I		cellular_component											owl:Class	
GO:0038016	biolink:NamedThing	insulin receptor internalization	A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell.	got7fsn_ti	insulin receptor endocytosis						bf	2011-06-23T04:24:52Z						biological_process											owl:Class	
GO:0031623	biolink:NamedThing	receptor internalization	A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0045579	biolink:NamedThing	positive regulation of B cell differentiation	Any process that activates or increases the frequency, rate or extent of B cell differentiation.	got7fsn_ti	up-regulation of B cell differentiation|upregulation of B cell differentiation|positive regulation of B-cell differentiation|up regulation of B cell differentiation|positive regulation of B-lymphocyte differentiation|positive regulation of B cell development|stimulation of B cell differentiation|activation of B cell differentiation|positive regulation of B lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1901096	biolink:NamedThing	regulation of autophagosome maturation	Any process that modulates the frequency, rate or extent of autophagosome maturation.	got7fsn_ti	regulation of amphisome-lysosome fusion|regulation of autolysosome formation|regulation of fusion of autophagosome with lysosome|regulation of autophagosome maturation|regulation of autophagosome fusion|regulation of autophagic vacuole fusion						lb	2012-07-10T07:22:01Z			GO:1902452			biological_process											owl:Class	
GO:0008922	biolink:NamedThing	long-chain fatty acid [acyl-carrier-protein] ligase activity	Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain-fatty-acid-acyl-carrier-protein ligase activity|acyl-acyl carrier protein synthetase|long-chain-fatty-acid-ACP ligase activity|acyl-ACP synthetase activity|stearoyl-ACP synthetase activity|long-chain-fatty-acid-[acyl-carrier protein] ligase activity|acyl-acyl-carrier-proteinsynthetase activity|long-chain fatty acid-[acyl-carrier-protein] ligase activity|long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity|long-chain-fatty-acid-[acyl-carrier-protein] ligase activity|acyl-[acyl-carrier-protein] synthetase activity|acyl-acyl-carrier-protein synthetase activity										GO:0010300	KEGG_REACTION:R07325|RHEA:45588|MetaCyc:ACYLACPSYNTH-RXN|EC:6.2.1.20		molecular_function											owl:Class	
GO:0001980	biolink:NamedThing	regulation of systemic arterial blood pressure by ischemic conditions	The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system.	got7fsn_ti	CNS ischemic response|ischemic regulation of systemic arterial blood pressure|ischemic control of blood pressure													biological_process											owl:Class	
GO:0044662	biolink:NamedThing	disruption by virus of host cell membrane	A process by which a virus has a negative effect on the functioning of a host cellular membrane.	got7fsn_ti	disruption by virus of host cell membrane|disruption by organism of host cell membrane						jl	2012-08-01T13:44:52Z						biological_process											owl:Class	
GO:0052025	biolink:NamedThing	modification by symbiont of host cell membrane	The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by symbiont of host cell membrane													biological_process											owl:Class	
GO:0002423	biolink:NamedThing	natural killer cell mediated immune response to tumor cell	An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.	got7fsn_ti														biological_process											owl:Class	
GO:0002418	biolink:NamedThing	immune response to tumor cell	An immune system process that functions in the response of an organism to a tumor cell.	got7fsn_ti														biological_process											owl:Class	
GO:0009933	biolink:NamedThing	meristem structural organization	Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.	got7fsn_ti	meristem organization|meristem organisation													biological_process											owl:Class	
GO:0047417	biolink:NamedThing	N-carbamoyl-D-amino acid hydrolase activity	Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid.	got7fsn_ti	N-carbamoyl-D-amino acid amidohydrolase activity											RHEA:11000|EC:3.5.1.77|MetaCyc:3.5.1.77-RXN		molecular_function											owl:Class	
GO:0055080	biolink:NamedThing	cation homeostasis	Any process involved in the maintenance of an internal steady state of cations within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0008764	biolink:NamedThing	UDP-N-acetylmuramoylalanine-D-glutamate ligase activity	Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate.	got7fsn_ti	UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming)|uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase activity|D-glutamate ligase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase activity|D-glutamate-adding enzyme activity|UDP-Mur-NAC-L-Ala:D-Glu ligase activity|MurD synthetase activity											KEGG_REACTION:R02783|MetaCyc:UDP-NACMURALA-GLU-LIG-RXN|EC:6.3.2.9|RHEA:16429		molecular_function											owl:Class	
GO:0044747	biolink:NamedThing	mature miRNA 3'-end processing	Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.	got7fsn_ti	miRNA 3' end terminal trimming|miRNA 3'-end processing|miRNA trimming						jl	2012-11-15T13:45:21Z						biological_process											owl:Class	
GO:1990467	biolink:NamedThing	NuA3a histone acetyltransferase complex	A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.	got7fsn_ti							rb	2014-08-25T23:07:45Z						cellular_component											owl:Class	
GO:0033100	biolink:NamedThing	NuA3 histone acetyltransferase complex	A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.	got7fsn_ti														cellular_component											owl:Class	
GO:0002064	biolink:NamedThing	epithelial cell development	The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.	got7fsn_ti														biological_process											owl:Class	
GO:0004381	biolink:NamedThing	fucosylgalactoside 3-alpha-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.	got7fsn_ti	histo-blood substance B-dependent galactosyltransferase activity|UDP-galactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity|UDPgalactose:O-alpha-L-fucosyl(1,2)D-galactose alpha-D-galactosyltransferase activity|UDP-galactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity|blood-group substance B-dependent galactosyltransferase activity|UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-galactosyltransferase activity|blood-group substance beta-dependent galactosyltransferase activity|histo-blood substance beta-dependent galactosyltransferase activity|fucosylglycoprotein 3-alpha-galactosyltransferase activity|B transferase activity|[blood group substance] alpha-galactosyltransferase activity|histo-blood group B transferase activity|UDPgalactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity|UDPgalactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity|UDPgalactose:O-alpha-L-fucosyl(1->2)D-galactose alpha-D-galactosyltransferase activity|glycoprotein-fucosylgalactoside alpha-galactosyltransferase activity											MetaCyc:2.4.1.37-RXN|Reactome:R-HSA-9034053|RHEA:14349|Reactome:R-HSA-9033961|EC:2.4.1.37		molecular_function											owl:Class	
GO:0103040	biolink:NamedThing	aldose sugar dehydrogenase activity	Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor.	got7fsn_ti												MetaCyc:RXN0-6371		molecular_function											owl:Class	
GO:0071431	biolink:NamedThing	tRNA-containing ribonucleoprotein complex export from nucleus	The directed movement of a ribonucleoprotein complex that contains transfer RNA from the nucleus to the cytoplasm.	got7fsn_ti	tRNA-containing ribonucleoprotein complex nucleus export|tRNA-containing RNP export from nucleus|tRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|tRNA-containing ribonucleoprotein complex export from cell nucleus						mah	2009-12-16T10:27:03Z						biological_process											owl:Class	
GO:0071194	biolink:NamedThing	Kv4.2-KChIP3 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2.	got7fsn_ti							mah	2009-11-23T04:58:41Z				CORUM:608		cellular_component											owl:Class	
GO:0048792	biolink:NamedThing	spontaneous exocytosis of neurotransmitter	The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell.	got7fsn_ti	spontaneous synaptic vesicle exocytosis													biological_process											owl:Class	
GO:0102997	biolink:NamedThing	progesterone 5beta- reductase activity	Catalysis of the reaction: H+ + progesterone + NADPH <=> 5beta-pregnane-3,20-dione + NADP.	got7fsn_ti												MetaCyc:RXN-9726		molecular_function											owl:Class	
GO:0036398	biolink:NamedThing	TCR signalosome	A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.	got7fsn_ti	LAT signalosome|linker for activation of T cells signalosome						bf	2013-07-18T13:52:24Z						cellular_component											owl:Class	
GO:0099571	biolink:NamedThing	postsynaptic cytoskeleton	The portion of the cytoskeleton contained within the postsynapse.	got7fsn_ti														cellular_component											owl:Class	
GO:0097119	biolink:NamedThing	postsynaptic density protein 95 clustering	The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.	got7fsn_ti	Dlg4 clustering|post-synaptic density protein 95 clustering|PSD-95 clustering						pr	2011-07-31T05:49:44Z						biological_process											owl:Class	
GO:0072657	biolink:NamedThing	protein localization to membrane	A process in which a protein is transported to, or maintained in, a specific location in a membrane.	got7fsn_ti	protein localization in membrane|protein localisation in membrane						mah	2011-02-14T02:35:18Z						biological_process											owl:Class	
GO:0042784	biolink:NamedThing	evasion of host immune response via regulation of host complement system	Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	active immune evasion via regulation of host complement system|active immune evasion via modulation of host complement system|active evasion of host immune response via regulation of host complement system|active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction										GO:0051811			biological_process											owl:Class	
GO:0042783	biolink:NamedThing	evasion of host immune response	A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	passive evasion of immune response of other organism involved in symbiotic interaction|mitigation of host immune response|immune evasion|active evasion of immune response of other organism involved in symbiotic interaction|passive evasion of host immune response|evasion or tolerance of host immune response|active immune evasion|active evasion of host immune response|passive immune evasion	https://github.com/geneontology/go-ontology/issues/17894|https://github.com/geneontology/go-ontology/issues/18357									GO:0020012|GO:0042782|GO:0051810|GO:0051809|GO:0051805			biological_process											owl:Class	
GO:0035355	biolink:NamedThing	Toll-like receptor 2-Toll-like receptor 6 protein complex	A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6).	got7fsn_ti	TLR6:TLR2 complex|TLR2:TLR6 heterodimer|TLR2-TLR6 protein complex|toll-like receptor TLR6:TLR2 heterodimeric complex						bf	2010-03-04T04:37:00Z			GO:0038126			cellular_component											owl:Class	
GO:0007567	biolink:NamedThing	parturition	The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs.	got7fsn_ti	giving birth|egg laying													biological_process											owl:Class	
GO:0044703	biolink:NamedThing	multi-organism reproductive process	A biological process that directly contributes to the process of producing new individuals, involving another organism.	got7fsn_ti							jl	2012-09-19T15:56:30Z						biological_process											owl:Class	
GO:0006836	biolink:NamedThing	neurotransmitter transport	The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.	got7fsn_ti	sodium:neurotransmitter transport													biological_process											owl:Class	
GO:0070290	biolink:NamedThing	N-acylphosphatidylethanolamine-specific phospholipase D activity	Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).	got7fsn_ti	N-acyl-phosphatidylethanolamine-specific phospholipase D activity|NAPE-specific phospholipase D activity											Reactome:R-HSA-2466831|EC:3.1.4.4		molecular_function											owl:Class	
GO:0031489	biolink:NamedThing	myosin V binding	Binding to a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.	got7fsn_ti														molecular_function											owl:Class	
GO:0060801	biolink:NamedThing	negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway	The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast.	got7fsn_ti	negative regulation of trophoblast cell differentiation by transforming growth factor beta signalling pathway						dph	2009-08-06T01:24:24Z						biological_process											owl:Class	
GO:0070369	biolink:NamedThing	beta-catenin-TCF7L2 complex	A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.	got7fsn_ti	beta-catenin-TCF4 complex													cellular_component											owl:Class	
GO:0045443	biolink:NamedThing	juvenile hormone secretion	The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:0090295	biolink:NamedThing	nitrogen catabolite repression of transcription	A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.	got7fsn_ti	nitrogen catabolite repression|negative regulation of transcription by nitrogen catabolites						tb	2010-02-24T02:31:53Z						biological_process											owl:Class	
GO:0090293	biolink:NamedThing	nitrogen catabolite regulation of transcription	A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.	got7fsn_ti	regulation of transcription by nitrogen catabolites						tb	2010-02-24T02:31:53Z						biological_process											owl:Class	
GO:0097733	biolink:NamedThing	photoreceptor cell cilium	A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment.	got7fsn_ti	photoreceptor cilium						pr	2016-09-30T10:50:11Z						cellular_component											owl:Class	
GO:0097731	biolink:NamedThing	9+0 non-motile cilium	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).	got7fsn_ti	9+0 immotile cilium|primary cilium|non-motile 9+0 cilium				This type of cilia may be present in solitary (authentic primary cilia in many cell types) or in multiple copies (e.g. in Grueneberg ganglion neurons).		pr	2016-09-29T14:05:03Z						cellular_component											owl:Class	
GO:0102659	biolink:NamedThing	UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 4-methylthiobutylhydroximate <=> H+ + 3-methylthiopropyl-desulfoglucosinolate + UDP.	got7fsn_ti												EC:2.4.1.195|MetaCyc:RXN-2208		molecular_function											owl:Class	
GO:1990446	biolink:NamedThing	U1 snRNP binding	Binding to a U1 small nuclear ribonucleoprotein particle.	got7fsn_ti							mah	2014-08-06T09:29:44Z						molecular_function											owl:Class	
GO:0090177	biolink:NamedThing	establishment of planar polarity involved in neural tube closure	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.	got7fsn_ti							tb	2009-12-14T10:38:46Z						biological_process											owl:Class	
GO:0009371	biolink:NamedThing	positive regulation of transcription by pheromones	Any process involving pheromones that activates or increases the rate of transcription.	got7fsn_ti	up regulation of transcription by pheromones|activation of transcription by pheromones|upregulation of transcription by pheromones|up-regulation of transcription by pheromones|stimulation of transcription by pheromones													biological_process											owl:Class	
GO:1990887	biolink:NamedThing	2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity	Catalysis of the reaction: 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol-n + S-adenosyl-L-homocysteine + H+.	got7fsn_ti							sl	2015-10-28T22:17:54Z						molecular_function											owl:Class	
GO:0000974	biolink:NamedThing	Prp19 complex	A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.	got7fsn_ti	nineteen complex|NTC|Prp19/CDC5 complex						krc	2009-10-12T10:01:30Z						cellular_component											owl:Class	
GO:0102587	biolink:NamedThing	cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) + trans-sinapate + H+.	got7fsn_ti												MetaCyc:RXN-15333		molecular_function											owl:Class	
GO:0034980	biolink:NamedThing	FHL2-CREB complex	A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation.	got7fsn_ti														cellular_component											owl:Class	
GO:0033202	biolink:NamedThing	DNA helicase complex	A protein complex that possesses DNA helicase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0102002	biolink:NamedThing	valine N-monooxygenase (oxime forming) activity	Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.	got7fsn_ti												RHEA:28606|MetaCyc:1.14.13.118-RXN|EC:1.14.14.38		molecular_function											owl:Class	
GO:0034916	biolink:NamedThing	2-methylhexanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-.	got7fsn_ti												UM-BBD_reactionID:r0928|EC:1.3.99.-		molecular_function											owl:Class	
GO:0036339	biolink:NamedThing	lymphocyte adhesion to endothelial cell of high endothelial venule	The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream.	got7fsn_ti	lymphocyte adhesion to HEV cell|lymphocyte adhesion to high endothelial venule				For the transition of leukocytes from rolling to adhered, consider instead annotating to 'leukocyte adhesive activation ; GO:0050902'.		bf	2012-09-10T16:00:23Z						biological_process											owl:Class	
GO:0140468	biolink:NamedThing	HRI-mediated signaling	A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock.	got7fsn_ti	EIF2AK1-mediated signaling	https://github.com/geneontology/go-ontology/issues/19153					pg	2020-05-26T08:46:15Z						biological_process											owl:Class	
GO:0140467	biolink:NamedThing	integrated stress response signaling	The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery.	got7fsn_ti	ISR	https://github.com/geneontology/go-ontology/issues/19153					pg	2020-05-26T08:04:10Z				Wikipedia:Integrated_stress_response		biological_process											owl:Class	
GO:0047488	biolink:NamedThing	heparin lyase activity	Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends.	got7fsn_ti	heparan sulfate lyase activity|heparinase activity|heparin eliminase activity											EC:4.2.2.7|MetaCyc:4.2.2.7-RXN		molecular_function											owl:Class	
GO:0030732	biolink:NamedThing	methionine S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine.	got7fsn_ti	S-adenosylmethionine transmethylase activity|methionine methyltransferase activity|S-adenosylmethionine-methionine methyltransferase activity|S-adenosyl methionine:methionine methyl transferase activity|S-adenosyl-L-methionine:L-methionine S-methyltransferase activity											RHEA:13761|MetaCyc:METHIONINE-S-METHYLTRANSFERASE-RXN|EC:2.1.1.12		molecular_function											owl:Class	
GO:0003861	biolink:NamedThing	3-isopropylmalate dehydratase activity	Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.	got7fsn_ti	alpha-IPM isomerase activity|beta-isopropylmalate dehydratase activity|(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)|alpha-isopropylmalate isomerase activity|(2R,3S)-3-isopropylmalate hydro-lyase activity|isopropylmalate isomerase activity											EC:4.2.1.33|RHEA:32287|MetaCyc:3-ISOPROPYLMALISOM-RXN		molecular_function											owl:Class	
GO:0050870	biolink:NamedThing	positive regulation of T cell activation	Any process that activates or increases the frequency, rate or extent of T cell activation.	got7fsn_ti	positive regulation of T-lymphocyte activation|positive regulation of T lymphocyte activation|up regulation of T cell activation|upregulation of T cell activation|stimulation of T cell activation|up-regulation of T cell activation|positive regulation of T-cell activation|activation of T cell activation													biological_process											owl:Class	
GO:0047384	biolink:NamedThing	[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity	Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)].	got7fsn_ti	hydroxymethylglutaryl-CoA reductase (NADPH)-phosphate phosphohydrolase activity|hydroxymethylglutaryl-CoA reductase (NADPH)-phosphatase activity|reductase phosphatase activity											MetaCyc:3.1.3.47-RXN|EC:3.1.3.47		molecular_function											owl:Class	
GO:0050286	biolink:NamedThing	sorbitol-6-phosphatase activity	Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate.	got7fsn_ti	sorbitol-6-phosphate phosphatase activity|sorbitol-6-phosphate phosphohydrolase activity											RHEA:24580|EC:3.1.3.50|KEGG_REACTION:R02866|MetaCyc:SORBITOL-6-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0033774	biolink:NamedThing	basal labyrinth	A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0072151	biolink:NamedThing	mesangial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell.	got7fsn_ti							mah	2010-02-24T02:11:13Z						biological_process											owl:Class	
GO:0052618	biolink:NamedThing	coenzyme F420-0:L-glutamate ligase activity	Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate.	got7fsn_ti												RHEA:30555|MetaCyc:RXN-8080|EC:6.3.2.31		molecular_function											owl:Class	
GO:0021770	biolink:NamedThing	parahippocampal gyrus development	The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.	got7fsn_ti	hippocampal gyrus development											Wikipedia:parahippocampal_gyrus		biological_process											owl:Class	
GO:0008036	biolink:NamedThing	diuretic hormone receptor activity	Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0015144	biolink:NamedThing	carbohydrate transmembrane transporter activity	Enables the transfer of carbohydrate from one side of a membrane to the other.	got7fsn_ti	carbohydrate transporter activity|sugar transporter										GO:1901476			molecular_function											owl:Class	
GO:0034793	biolink:NamedThing	cyclopropanecarboxylate-CoA ligase activity	Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-.	got7fsn_ti												UM-BBD_reactionID:r1056		molecular_function											owl:Class	
GO:0047271	biolink:NamedThing	glycosaminoglycan galactosyltransferase activity	Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP.	got7fsn_ti	UDPgalactose:glycosaminoglycan D-galactosyltransferase activity|uridine diphosphogalactose-mucopolysaccharide galactosyltransferase activity|UDP-galactose:glycosaminoglycan D-galactosyltransferase activity											EC:2.4.1.74|MetaCyc:2.4.1.74-RXN		molecular_function											owl:Class	
GO:0071266	biolink:NamedThing	'de novo' L-methionine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components.	got7fsn_ti	'de novo' L-methionine synthesis|'de novo' L-methionine anabolism|'de novo' L-methionine formation|'de novo' L-methionine biosynthesis						mah	2009-12-09T04:34:41Z						biological_process											owl:Class	
GO:0071265	biolink:NamedThing	L-methionine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.	got7fsn_ti	L-methionine anabolism|L-methionine biosynthesis|L-methionine synthesis|L-methionine formation						mah	2009-12-09T04:28:15Z						biological_process											owl:Class	
GO:0044375	biolink:NamedThing	regulation of peroxisome size	Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	got7fsn_ti							jl	2011-12-01T04:37:59Z						biological_process											owl:Class	
GO:0047198	biolink:NamedThing	cysteine-S-conjugate N-acetyltransferase activity	Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H(+).	got7fsn_ti	acetyl-CoA:S-substituted L-cysteine N-acetyltransferase activity											EC:2.3.1.80|RHEA:19213|KEGG_REACTION:R04950|MetaCyc:2.3.1.80-RXN|Reactome:R-HSA-5433066		molecular_function											owl:Class	
GO:1990784	biolink:NamedThing	response to dsDNA	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.	got7fsn_ti	response to double-stranded DNA						sl	2015-06-24T17:54:13Z						biological_process											owl:Class	
GO:0045836	biolink:NamedThing	positive regulation of meiotic nuclear division	Any process that activates or increases the frequency, rate or extent of meiosis.	got7fsn_ti	activation of meiosis|up-regulation of meiosis|upregulation of meiosis|positive regulation of meiosis|up regulation of meiosis|stimulation of meiosis													biological_process											owl:Class	
GO:0040020	biolink:NamedThing	regulation of meiotic nuclear division	Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.	got7fsn_ti	regulation of meiosis													biological_process											owl:Class	
GO:0005705	biolink:NamedThing	polytene chromosome interband	A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.	got7fsn_ti														cellular_component											owl:Class	
GO:0034399	biolink:NamedThing	nuclear periphery	The portion of the nuclear lumen proximal to the inner nuclear membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0009555	biolink:NamedThing	pollen development	The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.	got7fsn_ti	pollen grain formation|microgametophyte development|formation of generative and vegetative cells|male gametophyte development|male gametophyte formation										GO:0048231|GO:0009564			biological_process											owl:Class	
GO:0048229	biolink:NamedThing	gametophyte development	The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	gametogenesis													biological_process											owl:Class	
GO:0099154	biolink:NamedThing	serotonergic synapse	A synapse that uses serotonin as a neurotransmitter.	got7fsn_ti							dos	2017-07-05T14:22:05Z						cellular_component											owl:Class	
GO:0016152	biolink:NamedThing	mercury (II) reductase activity	Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH.	got7fsn_ti	mercury(II) reductase activity|Hg:NADP+ oxidoreductase activity|mer A|reduced NADP:mercuric ion oxidoreductase activity|mercuric reductase activity|mercuric ion reductase activity|mercury reductase activity|mercurate(II) reductase activity										GO:0018692	KEGG_REACTION:R02807|EC:1.16.1.1|MetaCyc:MERCURY-II-REDUCTASE-RXN|UM-BBD_reactionID:r0406|RHEA:23856		molecular_function											owl:Class	
GO:0001886	biolink:NamedThing	endothelial cell morphogenesis	The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.	got7fsn_ti														biological_process											owl:Class	
GO:0003382	biolink:NamedThing	epithelial cell morphogenesis	The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.	got7fsn_ti							dph	2009-12-09T07:21:06Z						biological_process											owl:Class	
GO:0044579	biolink:NamedThing	butyryl-CoA biosynthetic process from acetyl-CoA	The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA.	got7fsn_ti	butyryl-CoA biosynthesis from acetyl-CoA						jl	2012-04-19T04:25:07Z						biological_process											owl:Class	
GO:0006084	biolink:NamedThing	acetyl-CoA metabolic process	The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.	got7fsn_ti	acetyl coenzyme A metabolism|acetyl coenzyme A metabolic process|acetyl-CoA metabolism													biological_process											owl:Class	
GO:0051741	biolink:NamedThing	2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine.	got7fsn_ti	MPBQ methyltransferase activity											MetaCyc:RXN-2542|RHEA:37979		molecular_function											owl:Class	
GO:0031707	biolink:NamedThing	endothelin A receptor binding	Binding to an endothelin A receptor.	got7fsn_ti	endothelin A receptor ligand|endothelin-1 receptor binding													molecular_function											owl:Class	
GO:0035517	biolink:NamedThing	PR-DUB complex	A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.	got7fsn_ti	Polycomb repressive deubiquitinase complex						bf	2010-05-04T04:19:02Z						cellular_component											owl:Class	
GO:0031519	biolink:NamedThing	PcG protein complex	A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.	got7fsn_ti	Polycomb Group protein complex													cellular_component											owl:Class	
GO:0019988	biolink:NamedThing	charged-tRNA amino acid modification	The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.	got7fsn_ti	pre-translational protein modification|charged tRNA modification|pre-translational amino acid modification|pretranslation protein modification|charged-tRNA modification|pretranslational amino acid modification|charged tRNA amino acid modification										GO:0030630			biological_process											owl:Class	
GO:1990000	biolink:NamedThing	amyloid fibril formation	The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins.	got7fsn_ti	amyloid fibril assembly|amyloid structure assembly|amyloid structure formation				Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases  (PMID:22817896).		pr	2012-11-27T16:01:02Z						biological_process											owl:Class	
GO:0061450	biolink:NamedThing	trophoblast cell migration	Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.	got7fsn_ti							dph	2012-07-10T08:38:37Z						biological_process											owl:Class	
GO:0015968	biolink:NamedThing	stringent response	A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.	got7fsn_ti												Wikipedia:Stringent_response		biological_process											owl:Class	
GO:0097383	biolink:NamedThing	dIDP diphosphatase activity	Catalysis of the reaction: dIDP + H2O = dIMP + phosphate.	got7fsn_ti	deoxyinosine-diphosphatase activity						pr	2012-10-11T16:04:40Z				RHEA:35211|Reactome:R-HSA-2509793		molecular_function											owl:Class	
GO:0097382	biolink:NamedThing	deoxynucleoside-diphosphatase activity	Catalysis of the reaction: a deoxynucleoside diphosphate + H2O = a deoxynucleotide + phosphate.	got7fsn_ti							pr	2012-10-11T16:03:22Z						molecular_function											owl:Class	
GO:0070044	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-1a complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof).	got7fsn_ti	Snap25-Stx1a-Vamp2 complex|SNARE complex (Stx1a, SNAP25, VAMP)|SNARE complex (Snap25, Stx1a, Vamp2)|Stx1a-SNAP25-VAMP complex													cellular_component											owl:Class	
GO:0102622	biolink:NamedThing	linuron hydrolase activity	Catalysis of the reaction: linuron + H2O <=> N,O-dimethylhydroxylamine + carbon dioxide + 3,4-dichloroaniline.	got7fsn_ti												MetaCyc:RXN-15526		molecular_function											owl:Class	
GO:0048773	biolink:NamedThing	erythrophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance.	got7fsn_ti	erythrophore cell differentiation													biological_process											owl:Class	
GO:0097547	biolink:NamedThing	synaptic vesicle protein transport vesicle	A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon.	got7fsn_ti	STV				This term should not be confused with GO:0008021 'synaptic vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.		pr	2013-12-20T09:22:03Z						cellular_component											owl:Class	
GO:0016990	biolink:NamedThing	arginine deiminase activity	Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3.	got7fsn_ti	citrulline iminase activity|L-arginine deiminase activity|L-arginine iminohydrolase activity|arginine dihydrolase activity											RHEA:19597|EC:3.5.3.6|MetaCyc:ARGININE-DEIMINASE-RXN		molecular_function											owl:Class	
GO:0042132	biolink:NamedThing	fructose 1,6-bisphosphate 1-phosphatase activity	Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.	got7fsn_ti	FBPase activity|fructose 1,6-diphosphatase activity|D-fructose-1,6-bisphosphate 1-phosphohydrolase activity|fructose 1,6-diphosphate phosphatase activity|fructose 1,6-bisphosphate phosphatase activity|D-fructose 1,6-diphosphatase activity|hexose bisphosphatase activity|D-fructose-1,6-bisphosphate phosphatase activity|fructose diphosphatase activity|fructose bisphosphate phosphatase activity|hexosediphosphatase activity|fructose-1,6-bisphosphatase activity|fructose 1,6-bisphosphatase activity|fructose diphosphate phosphatase activity|fructose-bisphosphatase activity|hexose diphosphatase activity											EC:3.1.3.11|MetaCyc:F16BDEPHOS-RXN|RHEA:11064|Reactome:R-HSA-70479		molecular_function											owl:Class	
GO:0072263	biolink:NamedThing	metanephric intraglomerular mesangial cell proliferation	The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.	got7fsn_ti							mah	2010-03-30T02:27:53Z						biological_process											owl:Class	
GO:0072123	biolink:NamedThing	intraglomerular mesangial cell proliferation	The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.	got7fsn_ti							mah	2010-02-22T01:44:29Z						biological_process											owl:Class	
GO:0071086	biolink:NamedThing	alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.	got7fsn_ti	ITGA2b-ITGB3-CD9-GP1b-CD47 complex						mah	2009-11-06T04:45:08Z						cellular_component											owl:Class	
GO:0090665	biolink:NamedThing	glycoprotein complex	A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds.	got7fsn_ti					An example is the Dictyostelium multi protein pspB complex, which is secreted from prespore vesicles and incorporated into the spore coat.		tb	2015-12-11T17:45:23Z						cellular_component											owl:Class	
GO:0032369	biolink:NamedThing	negative regulation of lipid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	inhibition of lipid transport|down-regulation of lipid transport|down regulation of lipid transport|downregulation of lipid transport													biological_process											owl:Class	
GO:0032368	biolink:NamedThing	regulation of lipid transport	Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0047490	biolink:NamedThing	pectin lyase activity	Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends.	got7fsn_ti	PL activity|pectolyase activity|endo-pectin lyase activity|PNL activity|pectin trans-eliminase activity|polymethylgalacturonic transeliminase activity|PMGL activity|(1->4)-6-O-methyl-alpha-D-galacturonan lyase activity|pectin methyltranseliminase activity											EC:4.2.2.10|MetaCyc:4.2.2.10-RXN		molecular_function											owl:Class	
GO:0039526	biolink:NamedThing	modulation by virus of host apoptotic process	Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells.	got7fsn_ti	modulation by virus of host apoptosis|regulation by virus of host apoptosis|modulation of host cell apoptosis by virus						bf	2011-06-22T05:22:53Z				VZ:1581		biological_process											owl:Class	
GO:0034083	biolink:NamedThing	type III polyketide synthase complex	A polyketide synthase complex that consists of two identical ketosynthase polypeptides.	got7fsn_ti	type III polyketide synthase|type III PKS|type III PKS complex													cellular_component											owl:Class	
GO:0034081	biolink:NamedThing	polyketide synthase complex	A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.	got7fsn_ti	PKS complex|PKS													cellular_component											owl:Class	
GO:0071629	biolink:NamedThing	cytoplasm protein quality control by the ubiquitin-proteasome system	The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.	got7fsn_ti	cytoplasm-associated proteasomal ubiquitin-dependent protein breakdown|cytoplasm-associated proteasomal ubiquitin-dependent protein catabolism|cytoplasm-associated proteasomal ubiquitin-dependent protein degradation|ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome				See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.		mah	2010-02-11T03:06:57Z						biological_process											owl:Class	
GO:0140455	biolink:NamedThing	cytoplasm protein quality control	The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19172					pg	2020-04-20T15:46:20Z						biological_process											owl:Class	
GO:0031956	biolink:NamedThing	medium-chain fatty acid-CoA ligase activity	Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12.	got7fsn_ti	medium-chain-fatty-acid-CoA ligase activity|medium-chain fatty acid activation|medium-chain fatty-acid-CoA ligase activity	https://github.com/geneontology/go-ontology/issues/18967										EC:6.2.1.2|RHEA:48340		molecular_function											owl:Class	
GO:0090732	biolink:NamedThing	cofilin-actin rod	A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and disulfide cross-linked cofilin multimers.	got7fsn_ti							tb	2017-01-31T17:44:04Z						cellular_component											owl:Class	
GO:0031002	biolink:NamedThing	actin rod	A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Actin rod structures are found in diverse organisms, having been observed in spores of Dictyostelium discoideum, Drosophila melanogaster oocytes, as well as in numerous animal cells under stress conditions.	got7fsn_ti														cellular_component											owl:Class	
GO:0030149	biolink:NamedThing	sphingolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	got7fsn_ti	sphingolipid breakdown|sphingolipid degradation|sphingolipid catabolism													biological_process											owl:Class	
GO:0046466	biolink:NamedThing	membrane lipid catabolic process	The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.	got7fsn_ti	membrane lipid degradation|membrane lipid breakdown|membrane lipid catabolism|membrane lipid peroxidation													biological_process											owl:Class	
GO:0150024	biolink:NamedThing	oxidised low-density lipoprotein particle clearance	The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti	ox-LDL particle clearance|oxidised LDL particle clearance|oxLDL particle clearance|oxidized low-density lipoprotein particle clearance|oxidized LDL particle clearance						bc	2018-02-05T16:14:05Z						biological_process											owl:Class	
GO:0034381	biolink:NamedThing	plasma lipoprotein particle clearance	The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti	lipoprotein particle clearance													biological_process											owl:Class	
GO:0044719	biolink:NamedThing	regulation of imaginal disc-derived wing size	Any process that modulates the size of an imaginal disc-derived wing.	got7fsn_ti							jl	2012-10-18T13:49:12Z						biological_process											owl:Class	
GO:0061484	biolink:NamedThing	hematopoietic stem cell homeostasis	Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.	got7fsn_ti							dph	2012-12-04T09:41:02Z						biological_process											owl:Class	
GO:0099046	biolink:NamedThing	clearance of foreign intracellular nucleic acids	A defense process that protects an organism from DNA or RNA from an invading organism.	got7fsn_ti														biological_process											owl:Class	
GO:0043203	biolink:NamedThing	axon hillock	Portion of the neuronal cell soma from which the axon originates.	got7fsn_ti												NIF_Subcellular:sao627227260|Wikipedia:Axon_hillock		cellular_component											owl:Class	
GO:0047140	biolink:NamedThing	glutathione-CoA-glutathione transhydrogenase activity	Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.	got7fsn_ti	glutathione-coenzyme A glutathione disulfide transhydrogenase activity|glutathione:coenzyme A-glutathione transhydrogenase activity|CoA:glutathione-disulfide oxidoreductase activity|glutathione coenzyme A-glutathione transhydrogenase activity|coenzyme A:oxidized-glutathione oxidoreductase activity|coenzyme A:glutathione-disulfide oxidoreductase activity											RHEA:13125|EC:1.8.4.3|MetaCyc:1.8.4.3-RXN		molecular_function											owl:Class	
GO:1990787	biolink:NamedThing	negative regulation of hh target transcription factor activity	Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling.	got7fsn_ti	negative regulation of hedgehog target transcription factor						bhm	2015-06-26T09:54:29Z						biological_process											owl:Class	
GO:0051090	biolink:NamedThing	regulation of DNA-binding transcription factor activity	Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	got7fsn_ti	regulation of DNA binding transcription factor activity|regulation of thyroid hormone receptor activity|regulation of transcription factor activity|regulation of androgen receptor activity|regulation of sequence-specific DNA binding transcription factor activity										GO:1904167|GO:2000823			biological_process											owl:Class	
GO:0047069	biolink:NamedThing	7,8-dihydroxykynurenate 8,8a-dioxygenase activity	Catalysis of the reaction: 7,8-dihydroxykynurenate + O(2) = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+).	got7fsn_ti	7,8-dihydroxykynurenate:oxygen 8,8alpha-oxidoreductase (decyclizing)|7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)|7,8-dihydroxykynurenate oxygenase activity|7,8-dihydroxykynurenate 8,8alpha-dioxygenase activity											EC:1.13.11.10|MetaCyc:1.13.11.10-RXN|RHEA:23400|KEGG_REACTION:R03253		molecular_function											owl:Class	
GO:0018190	biolink:NamedThing	protein octanoylation	The modification of a protein amino acid by formation of an ester or amide with octanoic acid.	got7fsn_ti	protein amino acid octanoylation													biological_process											owl:Class	
GO:0050019	biolink:NamedThing	L-arabinitol 4-dehydrogenase activity	Catalysis of the reaction: L-arabinitol + NAD(+) = L-xylulose + H(+) + NADH.	got7fsn_ti												EC:1.1.1.12|RHEA:16381|KEGG_REACTION:R01903|MetaCyc:L-ARABINITOL-4-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0071027	biolink:NamedThing	nuclear RNA surveillance	The set of processes involved in identifying and degrading defective or aberrant RNAs within the nucleus.	got7fsn_ti	nuclear aberrant RNA catabolic process|nuclear RNA quality control						krc	2009-07-28T03:45:02Z						biological_process											owl:Class	
GO:0071025	biolink:NamedThing	RNA surveillance	The set of processes involved in identifying and degrading defective or aberrant RNAs.	got7fsn_ti	aberrant RNA catabolic process|RNA quality control						krc	2009-07-28T03:10:28Z						biological_process											owl:Class	
GO:0090539	biolink:NamedThing	peptide pheromone export by transmembrane transport	The directed movement of a peptide pheromone across a membrane and out of a cell.	got7fsn_ti	peptide pheromone export by membrane transport						tb	2013-02-11T15:44:51Z						biological_process											owl:Class	
GO:0000770	biolink:NamedThing	peptide pheromone export	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones.	got7fsn_ti	a-factor export										GO:0007325			biological_process											owl:Class	
GO:0090503	biolink:NamedThing	RNA phosphodiester bond hydrolysis, exonucleolytic	The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.	got7fsn_ti							tb	2012-10-22T12:05:27Z						biological_process											owl:Class	
GO:0090501	biolink:NamedThing	RNA phosphodiester bond hydrolysis	The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis.	got7fsn_ti							tb	2012-10-22T12:05:27Z						biological_process											owl:Class	
GO:0034062	biolink:NamedThing	5'-3' RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.	got7fsn_ti	ribonucleate nucleotidyltransferase activity|ribonucleic transcriptase activity|ribonucleic acid transcriptase activity|RNA transcriptase activity|ribonucleic polymerase activity|RNA polymerase activity|ribonucleic acid nucleotidyltransferase|C RNA formation factors|C ribonucleic acid formation factors|RNA nucleotidyltransferase activity|ribonucleic acid polymerase activity|ribonucleate polymerase activity|transcriptase											Reactome:R-HSA-6786881|Reactome:R-HSA-5696807		molecular_function											owl:Class	
GO:0047243	biolink:NamedThing	flavanone 7-O-beta-glucosyltransferase activity	Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP.	got7fsn_ti	naringenin 7-O-glucosyltransferase activity|hesperetin 7-O-glucosyl-transferase activity|UDPglucose:flavanone 7-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-flavanone 7-O-glucosyltransferase activity|UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase activity											MetaCyc:2.4.1.185-RXN|EC:2.4.1.185		molecular_function											owl:Class	
GO:0140591	biolink:NamedThing	nuclear envelope budding	The process by which large macromolecular complexes are budded through the inner nuclear membrane, into the perinuclear space, thus acquiring a membrane envelope. The enveloped particle fuses with the outer nuclear membrane and is released into the cytoplasm.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20782					pg	2021-02-08T08:31:06Z						biological_process											owl:Class	
GO:0051168	biolink:NamedThing	nuclear export	The directed movement of substances out of the nucleus.	got7fsn_ti	substance nuclear export|export from nucleus|nucleus export													biological_process											owl:Class	
GO:0009428	biolink:NamedThing	bacterial-type flagellum basal body, distal rod, P ring	One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer.	got7fsn_ti	flagellin-based flagellum basal body, distal rod, P ring|flagellar basal body, distal rod, P ring													cellular_component											owl:Class	
GO:0061522	biolink:NamedThing	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity	Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA.	got7fsn_ti							dph	2013-04-18T14:37:32Z						molecular_function											owl:Class	
GO:0031127	biolink:NamedThing	alpha-(1,2)-fucosyltransferase activity	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage.	got7fsn_ti	alpha-1,2-fucosyltransferase activity|alpha-(1->2)-fucosyltransferase activity													molecular_function											owl:Class	
GO:0000987	biolink:NamedThing	cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. The proximal promoter is in cis with and relatively close to the core promoter.	got7fsn_ti	enhancer sequence-specific DNA binding|proximal promoter sequence-specific DNA binding|enhancer binding|promoter proximal region sequence-specific DNA binding|cis-regulatory region binding|core promoter proximal region DNA binding|core promoter proximal region sequence-specific DNA binding						bf	2010-02-26T10:17:00Z			GO:0001159|GO:0001158|GO:0035326			molecular_function											owl:Class	
GO:0045967	biolink:NamedThing	negative regulation of growth rate	Any process that reduces the rate of growth of all or part of an organism.	got7fsn_ti	downregulation of growth rate|down-regulation of growth rate|inhibition of growth rate|down regulation of growth rate				Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation.									biological_process											owl:Class	
GO:0040009	biolink:NamedThing	regulation of growth rate	Any process that modulates the rate of growth of all or part of an organism.	got7fsn_ti					Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation.									biological_process											owl:Class	
GO:0004515	biolink:NamedThing	nicotinate-nucleotide adenylyltransferase activity	Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.	got7fsn_ti	ATP:nicotinate-nucleotide adenylyltransferase activity|deamido-NAD+ pyrophosphorylase activity|deamido-NAD(+) diphosphorylase activity|NaMN-ATase activity|deamido-NAD(+) pyrophosphorylase activity|nicotinate mononucleotide adenylyltransferase activity|nicotinic acid mononucleotide adenylyltransferase|deamidonicotinamide adenine dinucleotide pyrophosphorylase activity|ATP:nicotinate-ribonucleotide adenylyltransferase activity											MetaCyc:NICONUCADENYLYLTRAN-RXN|Reactome:R-HSA-200512|Reactome:R-HSA-197235|RHEA:22860|Reactome:R-HSA-200474|EC:2.7.7.18		molecular_function											owl:Class	
GO:0047654	biolink:NamedThing	alliin lyase activity	Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.	got7fsn_ti	alliinase activity|alkylcysteine sulfoxide lyase activity|S-alkylcysteine sulfoxide lyase activity|alliin alkyl-sulfenate-lyase activity|cysteine sulfoxide lyase activity|cysteine sulphoxide lyase activity|S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase (2-aminoacrylate-forming)|L-cysteine sulfoxide lyase activity											MetaCyc:ALLIIN-LYASE-RXN|EC:4.4.1.4|RHEA:20141		molecular_function											owl:Class	
GO:0045211	biolink:NamedThing	postsynaptic membrane	A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.	got7fsn_ti	post-synaptic membrane													cellular_component											owl:Class	
GO:0097060	biolink:NamedThing	synaptic membrane	A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.	got7fsn_ti							pr	2011-06-07T11:22:09Z						cellular_component											owl:Class	
GO:0102543	biolink:NamedThing	epsilon-rhodomycinone methylesterase activity	Catalysis of the reaction: epsilon-rhodomycinone + H2O <=> 15-demethoxy-epsilon-rhodomycinone + methanol + H+.	got7fsn_ti												MetaCyc:RXN-14865|EC:3.1.1.95		molecular_function											owl:Class	
GO:0016917	biolink:NamedThing	GABA receptor activity	Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.	got7fsn_ti	gamma-aminobutyric acid receptor activity|gamma-aminobutyrate binding|GABA binding|4-aminobutanoate receptor activity|gamma-aminobutyric acid binding|4-aminobutyrate receptor activity				See also the molecular function term 'neurotransmitter receptor activity ; GO:0030594'.									molecular_function											owl:Class	
GO:0070460	biolink:NamedThing	thyroid-stimulating hormone secretion	The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.	got7fsn_ti	thyroid stimulating hormone secretion|TSH secretion													biological_process											owl:Class	
GO:0102526	biolink:NamedThing	8-demethylnovobiocic acid C8-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 8-desmethylnovobiocic acid <=> S-adenosyl-L-homocysteine  + novobiocic acid + H+.	got7fsn_ti												EC:2.1.1.284|RHEA:36651|MetaCyc:RXN-14543		molecular_function											owl:Class	
GO:0004858	biolink:NamedThing	dUTP pyrophosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of dUTP pyrophosphatase.	got7fsn_ti														molecular_function											owl:Class	
GO:0042442	biolink:NamedThing	melatonin catabolic process	The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine).	got7fsn_ti	melatonin degradation|melatonin breakdown|melatonin catabolism										GO:0042449			biological_process											owl:Class	
GO:0047333	biolink:NamedThing	dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity	Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H(+).	got7fsn_ti	dihydrostreptomycin 6-phosphate kinase (phosphorylating)|dihydrostreptomycin-6-phosphate 3'alpha-kinase activity|ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase activity|ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase activity											EC:2.7.1.88|KEGG_REACTION:R03395|RHEA:16281|MetaCyc:2.7.1.88-RXN		molecular_function											owl:Class	
GO:0034071	biolink:NamedThing	aminoglycoside phosphotransferase activity	Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside.	got7fsn_ti	aminoglycoside kinase activity											EC:2.7.1.-		molecular_function											owl:Class	
GO:0097258	biolink:NamedThing	20-hydroxy-leukotriene B4 omega oxidase activity	Catalysis of the reaction:  20-hydroxy-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-oxo-leukotriene B4 + H+ + 2 H2O + oxidized [NADPH-hemoprotein reductase].	got7fsn_ti	20-hydroxy-leukotriene B4 omega-oxidase activity|20-hydroxy-leukotriene B4 omega-oxidation						pr	2012-03-07T03:37:53Z				RHEA:48668|Reactome:R-HSA-2161745		molecular_function											owl:Class	
GO:0017184	biolink:NamedThing	peptidyl-diphthamide catabolic process	The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue.	got7fsn_ti	peptidyl-diphthamide degradation|peptidyl-diphthamide catabolism|peptidyl-diphthamide breakdown													biological_process											owl:Class	
GO:0033883	biolink:NamedThing	pyridoxal phosphatase activity	Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.	got7fsn_ti	PNP phosphatase activity|pyridoxal-5'-phosphate phosphohydrolase activity|PLP phosphatase activity|vitamin B6-phosphate phosphatase activity|vitamin B6 (pyridoxine) phosphatase activity											MetaCyc:3.1.3.74-RXN|EC:3.1.3.74|RHEA:20533		molecular_function											owl:Class	
GO:0097432	biolink:NamedThing	hippocampal pyramidal neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.	got7fsn_ti							pr	2012-11-22T09:33:31Z						biological_process											owl:Class	
GO:0021859	biolink:NamedThing	pyramidal neuron differentiation	The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.	got7fsn_ti	projection neuron differentiation													biological_process											owl:Class	
GO:0033990	biolink:NamedThing	ectoine synthase activity	Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H(2)O.	got7fsn_ti	EctC|N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity|L-ectoine synthase activity|4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity|N-acetyldiaminobutyrate dehydratase activity|N-acetyldiaminobutanoate dehydratase activity											MetaCyc:R103-RXN|RHEA:17281|EC:4.2.1.108|KEGG_REACTION:R06979		molecular_function											owl:Class	
GO:0072222	biolink:NamedThing	metanephric early distal convoluted tubule development	The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.	got7fsn_ti							mah	2010-03-18T03:35:46Z						biological_process											owl:Class	
GO:0072067	biolink:NamedThing	early distal convoluted tubule development	The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.	got7fsn_ti							mah	2010-01-25T04:15:17Z						biological_process											owl:Class	
GO:0047713	biolink:NamedThing	galactitol 2-dehydrogenase activity	Catalysis of the reaction: galactitol + NAD(+) = D-tagatose + H(+) + NADH.	got7fsn_ti												MetaCyc:GALACTITOL-2-DEHYDROGENASE-RXN|EC:1.1.1.16|KEGG_REACTION:R02928|RHEA:20685		molecular_function											owl:Class	
GO:0061273	biolink:NamedThing	mesonephric distal tubule morphogenesis	The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.	got7fsn_ti							dph	2010-09-02T12:12:00Z						biological_process											owl:Class	
GO:0075035	biolink:NamedThing	appressorium maturation	The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	maturation of appressorium on or near host|appressorium maturation on or near host|maturation of symbiont appressorium on or near host													biological_process											owl:Class	
GO:0098995	biolink:NamedThing	disruption by virus of host envelope lipopolysaccharide during virus entry	The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell.  For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides.	got7fsn_ti	degradation of host lipopolysaccharide during virus entry|disassembly by virus of outer membrane lipopolysaccharide during viral entry|degradation of host cell envelope lipopolysaccharide during viral entry											VZ:3939		biological_process											owl:Class	
GO:0061899	biolink:NamedThing	11-cis-retinal 3,4-desaturase activity	Catalysis of the reaction: 11-cis-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin].	got7fsn_ti							dph	2017-06-12T15:03:57Z						molecular_function											owl:Class	
GO:1990868	biolink:NamedThing	response to chemokine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.	got7fsn_ti							sl	2015-09-25T16:37:00Z						biological_process											owl:Class	
GO:1990172	biolink:NamedThing	G protein-coupled receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor.	got7fsn_ti	G-protein coupled receptor catabolic process						sp	2013-08-22T10:16:58Z						biological_process											owl:Class	
GO:0098884	biolink:NamedThing	postsynaptic neurotransmitter receptor internalization	A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle.	got7fsn_ti	postsynaptic neurotransmitter receptor endocytosis	https://github.com/geneontology/synapse/issues/230												biological_process											owl:Class	
GO:0008758	biolink:NamedThing	UDP-2,3-diacylglucosamine hydrolase activity	Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP.	got7fsn_ti												MetaCyc:LIPIDXSYNTHESIS-RXN|RHEA:25213		molecular_function											owl:Class	
GO:0046948	biolink:NamedThing	hydroxylysine catabolic process	The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.	got7fsn_ti	hydroxylysine degradation|hydroxylysine catabolism|hydroxylysine breakdown													biological_process											owl:Class	
GO:0009068	biolink:NamedThing	aspartate family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.	got7fsn_ti	aspartate family amino acid breakdown|aspartate family amino acid degradation|aspartate family amino acid catabolism													biological_process											owl:Class	
GO:0097193	biolink:NamedThing	intrinsic apoptotic signaling pathway	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).	got7fsn_ti	intrinsic apoptosis|induction of apoptosis by intracellular signals|intrinsic apoptotic signalling pathway|intrinsic apoptotic pathway|mitochondrial-mediated apoptotic pathway				The signals that start intrinsic apoptosis may come from extracellular sources (e.g. oxidative stress, UV exposure), but the reception of the signal and thus the signaling pathway start inside the cell (as a result of DNA damage, redox imbalance, etc.). Examples are ZPR9 (ZNF622) and ASK1 (MAP3K5) (UniProt symbols Q969S3 and Q99683) in PMID:21771788. A diagram of the intrinsic apoptotic pathway including examples of molecular players can be found in Figure 2 in PMID:21760595.		pr	2011-11-23T09:40:50Z			GO:0008629			biological_process											owl:Class	
GO:0048101	biolink:NamedThing	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity	Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive.	got7fsn_ti	calcium- and calmodulin-regulated cGMP-specific phosphodiesterase activity|calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity|calcium- and calmodulin-regulated cGMP phosphodiesterase activity|calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity													molecular_function											owl:Class	
GO:0047555	biolink:NamedThing	3',5'-cyclic-GMP phosphodiesterase activity	Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.	got7fsn_ti	guanosine cyclic 3',5'-phosphate phosphodiesterase activity|cyclic guanosine 3',5'-monophosphate phosphodiesterase activity|cyclic 3',5'-GMP phosphodiesterase activity|cyclic GMP phosphodiesterase activity|cGMP-PDE|3',5'-cyclic-GMP 5'-nucleotidohydrolase activity|cGMP phosphodiesterase activity|cGMP-specific phosphodiesterase activity|cyclic guanosine 3',5'-phosphate phosphodiesterase activity|3',5' cyclic-GMP phosphodiesterase activity										GO:0004116	MetaCyc:35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN|Reactome:R-HSA-74059|EC:3.1.4.35|RHEA:16957|Reactome:R-HSA-4086392|Reactome:R-HSA-418456		molecular_function											owl:Class	
GO:0030787	biolink:NamedThing	inositol 4-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase activity|myo-inositol 6-O-methyltransferase activity|myo-inositol 4-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase activity											MetaCyc:2.1.1.129-RXN|RHEA:23248|EC:2.1.1.129|KEGG_REACTION:R01190		molecular_function											owl:Class	
GO:0033409	biolink:NamedThing	UAU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UAU codon.	got7fsn_ti	tyrosine tRNA|TAT codon-amino acid adaptor activity				Note that in the standard genetic code, TAT codes for tyrosine.									molecular_function											owl:Class	
GO:0071840	biolink:NamedThing	cellular component organization or biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.	got7fsn_ti	cellular component organisation or biogenesis at cellular level|cellular component organization or biogenesis at cellular level|cellular component organisation or biogenesis						mah	2010-09-10T01:39:16Z			GO:0071841			biological_process											owl:Class	
GO:0033904	biolink:NamedThing	dextranase activity	Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran.	got7fsn_ti	DL 2|alpha-D-1,6-glucan-6-glucanohydrolase activity|1,6-alpha-D-glucan 6-glucanohydrolase activity|alpha-1,6-glucan-6-glucanohydrolase activity|dextran hydrolase activity|dextranase DL 2 activity|endodextranase activity|endo-dextranase activity											EC:3.2.1.11|MetaCyc:3.2.1.11-RXN		molecular_function											owl:Class	
GO:0043729	biolink:NamedThing	2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity	Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + formate.	got7fsn_ti														molecular_function											owl:Class	
GO:0044165	biolink:NamedThing	host cell endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).	got7fsn_ti	host endoplasmic reticulum						jl	2009-09-04T11:08:09Z						cellular_component											owl:Class	
GO:0060060	biolink:NamedThing	post-embryonic retina morphogenesis in camera-type eye	The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage.	got7fsn_ti														biological_process											owl:Class	
GO:0019907	biolink:NamedThing	cyclin-dependent protein kinase activating kinase holoenzyme complex	A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH.	got7fsn_ti	CDK-activating kinase complex|CAK complex													cellular_component											owl:Class	
GO:0018996	biolink:NamedThing	molting cycle, collagen and cuticulin-based cuticle	The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans.	got7fsn_ti	collagen and cuticulin-based cuticle molting cycle													biological_process											owl:Class	
GO:0042303	biolink:NamedThing	molting cycle	The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.	got7fsn_ti														biological_process											owl:Class	
GO:1902426	biolink:NamedThing	deactivation of mitotic spindle assembly checkpoint	A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.	got7fsn_ti	inhibition of mitotic cell cycle spindle assembly checkpoint|negative regulation of mitotic cell cycle spindle assembly checkpoint|downregulation of Mad2-dependent checkpoint|down regulation of mitotic cell cycle spindle assembly checkpoint|down regulation of mitotic spindle assembly checkpoint|down-regulation of mitotic spindle assembly checkpoint|negative regulation of mitotic spindle assembly checkpoint|down-regulation of Mad2-dependent checkpoint|inhibition of mitotic spindle assembly checkpoint|down regulation of Mad2-dependent checkpoint|inhibition of Mad2-dependent checkpoint|downregulation of mitotic cell cycle spindle assembly checkpoint|negative regulation of Mad2-dependent checkpoint|downregulation of mitotic spindle assembly checkpoint|mitotic spindle assembly deactivation|down-regulation of mitotic cell cycle spindle assembly checkpoint|mitotic spindle assembly checkpoint silencing				A mitotic spindle assembly checkpoint is either activated or switched off; no other means of reducing the frequency, rate or extent of this process are currently known.		dph	2013-09-20T18:42:07Z						biological_process											owl:Class	
GO:0045931	biolink:NamedThing	positive regulation of mitotic cell cycle	Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.	got7fsn_ti	up-regulation of progression through mitotic cell cycle|positive regulation of progression through mitotic cell cycle|stimulation of progression through mitotic cell cycle|activation of progression through mitotic cell cycle|up regulation of progression through mitotic cell cycle|positive regulation of mitotic cell cycle progression|upregulation of progression through mitotic cell cycle													biological_process											owl:Class	
GO:0102367	biolink:NamedThing	2-alpha-hydroxytaxusin 7-beta-hydroxylase activity	Catalysis of the reaction: 2alpha-hydroxytaxusin + NADPH + O2 + H+ <=> 2alpha, 7beta-dihydroxytaxusin + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-13488		molecular_function											owl:Class	
GO:0048758	biolink:NamedThing	companion cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member.	got7fsn_ti														biological_process											owl:Class	
GO:0048760	biolink:NamedThing	plant parenchymal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure.	got7fsn_ti	parenchymal cell differentiation													biological_process											owl:Class	
GO:0004805	biolink:NamedThing	trehalose-phosphatase activity	Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate.	got7fsn_ti	trehalose 6-phosphatase activity|trehalose-6-phosphate phosphohydrolase activity|trehalose 6-phosphate phosphatase activity|trehalose phosphatase activity											EC:3.1.3.12|MetaCyc:TREHALOSEPHOSPHA-RXN|RHEA:23420		molecular_function											owl:Class	
GO:0044576	biolink:NamedThing	pentose catabolic process to ethanol	The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol.	got7fsn_ti	pentose catabolism to ethanol						jl	2012-04-19T03:46:37Z						biological_process											owl:Class	
GO:0006115	biolink:NamedThing	ethanol biosynthetic process	The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.	got7fsn_ti	ethanol anabolism|ethanol formation|ethanol biosynthesis|ethanol synthesis													biological_process											owl:Class	
GO:0070549	biolink:NamedThing	negative regulation of translation involved in RNA interference	A process of negative regulation of translation that is mediated by the association of small interfering RNAs (siRNAs) with a cognate target mRNA.	got7fsn_ti	RNA interference, negative regulation of translation|inhibition of translation involved in RNA interference|down-regulation of translation involved in RNA interference|down regulation of translation involved in RNA interference|downregulation of translation involved in RNA interference													biological_process											owl:Class	
GO:0040033	biolink:NamedThing	negative regulation of translation, ncRNA-mediated	Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein.	got7fsn_ti	inhibition of mRNA translation, ncRNA-mediated|downregulation of mRNA translation, ncRNA-mediated|down-regulation of mRNA translation, ncRNA-mediated|down regulation of mRNA translation, ncRNA-mediated													biological_process											owl:Class	
GO:0022616	biolink:NamedThing	DNA strand elongation	The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12633												biological_process											owl:Class	
GO:0032632	biolink:NamedThing	interleukin-3 production	The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-3 production|interleukin-3 secretion|interleukin-3 biosynthetic process										GO:0042223|GO:0072601			biological_process											owl:Class	
GO:0120282	biolink:NamedThing	autolysosome lumen	The volume that is enclosed within the autolysosome single-membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20239					krc	2020-11-17T02:53:51Z						cellular_component											owl:Class	
GO:0005775	biolink:NamedThing	vacuolar lumen	The volume enclosed within the vacuolar membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0004427	biolink:NamedThing	inorganic diphosphatase activity	Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate.	got7fsn_ti	pyrophosphate phosphohydrolase activity|diphosphate phosphohydrolase activity|inorganic pyrophosphatase activity											Reactome:R-HSA-71732|Reactome:R-HSA-6788912|Reactome:R-HSA-449937|EC:3.6.1.1|MetaCyc:INORGPYROPHOSPHAT-RXN|RHEA:24576|KEGG_REACTION:R00004		molecular_function											owl:Class	
GO:0102489	biolink:NamedThing	GTP phosphohydrolase activity	Catalysis of the reaction: GTP + 2 H2O = GMP + 2 hydrogenphosphate + 2 H+.	got7fsn_ti												EC:3.6.1.5|MetaCyc:RXN-14201		molecular_function											owl:Class	
GO:1990587	biolink:NamedThing	FtsQBL complex	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB, FtsL and FtsQ.	got7fsn_ti	FtsB-FtsL-FtsQ complex				An example of this is FtsB in E. coli (P0A6S5) in PMID:15165235 (inferred from physical interaction).		bhm	2014-12-15T09:25:09Z						cellular_component											owl:Class	
GO:1990586	biolink:NamedThing	divisome complex	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells.	got7fsn_ti							bhm	2014-12-15T09:13:38Z						cellular_component											owl:Class	
GO:0071335	biolink:NamedThing	hair follicle cell proliferation	The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population.	got7fsn_ti							mah	2009-12-11T10:49:53Z						biological_process											owl:Class	
GO:0047721	biolink:NamedThing	indoleacetate-lysine synthetase activity	Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H(+) + phosphate.	got7fsn_ti	(indol-3-yl)acetate:L-lysine ligase (ADP-forming)|indoleacetate:L-lysine ligase (ADP-forming)|N-(indole-3-acetyl)-L-lysine synthetase activity|indoleacetate-lysine ligase activity|IAA-lysine synthetase activity											KEGG_REACTION:R03095|EC:6.3.2.20|MetaCyc:INDOLEACETATE--LYSINE-LIGASE-RXN|RHEA:14857		molecular_function											owl:Class	
GO:0010279	biolink:NamedThing	indole-3-acetic acid amido synthetase activity	Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate.	got7fsn_ti	IAA amino acid conjugate synthetase activity|IAA amido synthetase activity|IAA amino acid synthetase activity													molecular_function											owl:Class	
GO:0016532	biolink:NamedThing	superoxide dismutase copper chaperone activity	A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.	got7fsn_ti					See also the molecular function term 'superoxide dismutase activity ; GO:0004784'.									molecular_function											owl:Class	
GO:0016531	biolink:NamedThing	copper chaperone activity	Directly binding to and delivering copper ions to a target protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0033857	biolink:NamedThing	diphosphoinositol-pentakisphosphate kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.	got7fsn_ti	PPIP5K2|PP-InsP5 kinase activity|PPIP5K|VIP1|VIP2|ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase activity|PP-IP5 kinase activity|PPIP5K1											EC:2.7.4.24		molecular_function											owl:Class	
GO:0004693	biolink:NamedThing	cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	got7fsn_ti	cyclin-dependent protein kinase, intrinsic catalyst activity|cyclin-A associated kinase activity|D-type cyclin kinase activity|cyclin-dependent kinase activity|neuronal cdc2-like kinase activity|Cdk-activating protein kinase activity|cyclin D-cdk6 kinase activity|CDK activity|cyclin-dependent kinase 6 activity|cyclin-dependent kinase-2 activity|cdk-activating kinase activity|cdc2 kinase activity|cyclin-dependent kinase-4 activity|ATP:cyclin phosphotransferase activity|cyclin E kinase activity|CDK, catalytic subunit activity|cyclin D-dependent kinase activity|cyclin-dependent protein kinase activity|CDK				This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).						GO:0016537	Reactome:R-HSA-6805109|Reactome:R-HSA-69227|Reactome:R-HSA-69756|Reactome:R-HSA-2430533|Reactome:R-HSA-180047|Reactome:R-HSA-187959|Reactome:R-HSA-5244669|Reactome:R-HSA-187520|Reactome:R-HSA-174122|Reactome:R-HSA-9008412|Reactome:R-HSA-5195402|MetaCyc:2.7.11.22-RXN|Reactome:R-HSA-2468287|Reactome:R-HSA-69754|Reactome:R-HSA-4086410|Reactome:R-HSA-9624800|Reactome:R-HSA-2984220|Reactome:R-HSA-69005|Reactome:R-HSA-1226095|Reactome:R-HSA-2990882|Reactome:R-HSA-2172183|Reactome:R-HSA-6793661|Reactome:R-HSA-174132|Reactome:R-HSA-68944|Reactome:R-HSA-1226094|Reactome:R-HSA-6797606|Reactome:R-HSA-2245218|Reactome:R-HSA-187948|Reactome:R-HSA-9686521|Reactome:R-HSA-5692755|Reactome:R-HSA-188390|Reactome:R-HSA-380278|Reactome:R-HSA-1912391|Reactome:R-HSA-2220971|Reactome:R-HSA-187916|Reactome:R-HSA-174079|Reactome:R-HSA-4088024|Reactome:R-HSA-2468293|EC:2.7.11.22|Reactome:R-HSA-2294600|Reactome:R-HSA-2514854|Reactome:R-HSA-3788705|Reactome:R-HSA-174251|Reactome:R-HSA-9009282		molecular_function											owl:Class	
GO:0097472	biolink:NamedThing	cyclin-dependent protein kinase activity	Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.	got7fsn_ti					This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).		pr	2013-03-06T13:46:04Z						molecular_function											owl:Class	
GO:0018599	biolink:NamedThing	2-hydroxyisobutyrate 3-monooxygenase activity	Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate.	got7fsn_ti												UM-BBD_reactionID:r0619		molecular_function											owl:Class	
GO:0072402	biolink:NamedThing	response to DNA integrity checkpoint signaling	A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling.	got7fsn_ti	response to signal involved in DNA integrity checkpoint|DNA integrity checkpoint effector process						mah	2010-12-08T03:32:17Z						biological_process											owl:Class	
GO:0045905	biolink:NamedThing	positive regulation of translational termination	Any process that activates or increases the frequency, rate or extent of translational termination.	got7fsn_ti	activation of translational termination|up-regulation of translational termination|upregulation of translational termination|stimulation of translational termination|up regulation of translational termination													biological_process											owl:Class	
GO:0007529	biolink:NamedThing	establishment of synaptic specificity at neuromuscular junction	The biological process in which a synapse between a motor neuron and a muscle is initially formed.	got7fsn_ti														biological_process											owl:Class	
GO:0034990	biolink:NamedThing	nuclear mitotic cohesin complex	A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.	got7fsn_ti					Note that this term should be used to annotate gene products found in cohesin complexes in organisms that undergo closed mitosis (i. e. where the nuclear envelope does not break down, as in fungi). For organisms in which the nuclear envelope breaks down during mitosis, the parent should be used.									cellular_component											owl:Class	
GO:0000798	biolink:NamedThing	nuclear cohesin complex	A cohesin complex required for cohesion between sister chromatids that remain in the nucleus.	got7fsn_ti					Note that this term and its children should be used to annotate gene products found in cohesin complexes in organisms that undergo closed mitosis (i.e. where the nuclear envelope does not break down, as in fungi). For organisms in which the nuclear envelope breaks down during mitosis, the parent should be used.									cellular_component											owl:Class	
GO:0071597	biolink:NamedThing	cellular birth scar	Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation.	got7fsn_ti							mah	2010-02-02T02:42:44Z						cellular_component											owl:Class	
GO:0021675	biolink:NamedThing	nerve development	The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0030685	biolink:NamedThing	nucleolar preribosome	Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0006186	biolink:NamedThing	dGDP phosphorylation	The process of introducing a phosphate group into dGDP, deoxyguanosine diphosphate, to produce dGTP.	got7fsn_ti														biological_process											owl:Class	
GO:0009216	biolink:NamedThing	purine deoxyribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside triphosphate biosynthesis|purine deoxyribonucleoside triphosphate formation|purine deoxyribonucleoside triphosphate anabolism|purine deoxyribonucleoside triphosphate synthesis													biological_process											owl:Class	
GO:0031209	biolink:NamedThing	SCAR complex	A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.	got7fsn_ti	WAVE complex|WAVE regulatory complex|WRC													cellular_component											owl:Class	
GO:0009927	biolink:NamedThing	histidine phosphotransfer kinase activity	Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15611												molecular_function											owl:Class	
GO:0060089	biolink:NamedThing	molecular transducer activity	A compound molecular function in which an effector function is controlled by one or more regulatory components.	got7fsn_ti														molecular_function											owl:Class	
GO:0000814	biolink:NamedThing	ESCRT II complex	An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.	got7fsn_ti	endosomal sorting complex required for transport													cellular_component											owl:Class	
GO:0036452	biolink:NamedThing	ESCRT complex	An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes.	got7fsn_ti	endosomal sorting complex required for transport						bf	2013-11-06T16:25:52Z				Wikipedia:ESCRT		cellular_component											owl:Class	
GO:0050816	biolink:NamedThing	phosphothreonine residue binding	Binding to a phosphorylated threonine residue within a protein.	got7fsn_ti	phosphothreonine binding													molecular_function											owl:Class	
GO:0045309	biolink:NamedThing	protein phosphorylated amino acid binding	Binding to a phosphorylated amino acid residue within a protein.	got7fsn_ti	phosphoprotein amino acid binding													molecular_function											owl:Class	
GO:0004451	biolink:NamedThing	isocitrate lyase activity	Catalysis of the reaction: isocitrate = glyoxylate + succinate.	got7fsn_ti	threo-DS-isocitrate glyoxylate-lyase activity|isocitrate glyoxylate-lyase activity|isocitratase activity|isocitrate glyoxylate-lyase (succinate-forming)|ICL activity|isocitritase activity|isocitrase activity											MetaCyc:ISOCIT-CLEAV-RXN|RHEA:13245|KEGG_REACTION:R00479|EC:4.1.3.1		molecular_function											owl:Class	
GO:0032923	biolink:NamedThing	organic phosphonate biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.	got7fsn_ti	organophosphonate biosynthetic process													biological_process											owl:Class	
GO:0042816	biolink:NamedThing	vitamin B6 metabolic process	The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	got7fsn_ti	vitamin B6 metabolism													biological_process											owl:Class	
GO:0048072	biolink:NamedThing	compound eye pigmentation	Establishment of a pattern of pigment in the compound eye.	got7fsn_ti														biological_process											owl:Class	
GO:0047157	biolink:NamedThing	myelin-proteolipid O-palmitoyltransferase activity	Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA.	got7fsn_ti	palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase activity|myelin PLP acyltransferase activity|acyl-protein synthase activity|[myelin-proteolipid] O-palmitoyltransferase activity	https://github.com/geneontology/go-ontology/issues/21319										EC:2.3.1.100|MetaCyc:2.3.1.100-RXN		molecular_function											owl:Class	
GO:0032609	biolink:NamedThing	interferon-gamma production	The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.	got7fsn_ti	interferon-gamma secretion|IFNG production|type II IFN production|interferon-gamma biosynthetic process|type II interferon production										GO:0072643|GO:0042095			biological_process											owl:Class	
GO:0061059	biolink:NamedThing	positive regulation of peptidoglycan recognition protein signaling pathway	Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.	got7fsn_ti	positive regulation of peptidoglycan recognition protein signalling pathway						dph	2010-03-02T12:37:44Z						biological_process											owl:Class	
GO:0002833	biolink:NamedThing	positive regulation of response to biotic stimulus	Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.	got7fsn_ti	up regulation of response to biotic stimulus|up-regulation of response to biotic stimulus|upregulation of response to biotic stimulus|activation of response to biotic stimulus|stimulation of response to biotic stimulus				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0031820	biolink:NamedThing	P2Y11 nucleotide receptor binding	Binding to a P2Y11 nucleotide receptor.	got7fsn_ti	P2Y11 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0071038	biolink:NamedThing	nuclear polyadenylation-dependent tRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA.	got7fsn_ti	nuclear poly(A)-dependent tRNA catabolic process						krc	2009-07-29T01:08:14Z						biological_process											owl:Class	
GO:0106354	biolink:NamedThing	tRNA surveillance	The set of processes involved in identifying and degrading defective or aberrant tRNAs.	got7fsn_ti							hjd	2021-01-27T16:29:46Z						biological_process											owl:Class	
GO:0048148	biolink:NamedThing	behavioral response to cocaine	Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.	got7fsn_ti	behavioural response to cocaine													biological_process											owl:Class	
GO:0051601	biolink:NamedThing	exocyst localization	Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.	got7fsn_ti	establishment and maintenance of exocyst localization|exocyst localisation													biological_process											owl:Class	
GO:0014864	biolink:NamedThing	detection of muscle activity	The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0014865	biolink:NamedThing	detection of activity	The series of events in which an activity stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0003413	biolink:NamedThing	chondrocyte differentiation involved in endochondral bone morphogenesis	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti							dph	2009-12-22T08:39:58Z						biological_process											owl:Class	
GO:0033840	biolink:NamedThing	NDP-glucose-starch glucosyltransferase activity	Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1.	got7fsn_ti	waxy protein|GBSS|NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|granule-bound starch synthase activity|starch synthase II activity|NDPglucose-starch glucosyltransferase activity|GBSSI|granule-bound starch synthase II activity|GBSSII|starch granule-bound nucleoside diphosphate glucose-starch glucosyltransferase activity|granule-bound starch synthase I activity											MetaCyc:2.4.1.242-RXN|EC:2.4.1.242|RHEA:15873		molecular_function											owl:Class	
GO:0004934	biolink:NamedThing	mating-type alpha-factor pheromone receptor activity	Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity.	got7fsn_ti	class D G-protein-coupled receptor activity|class D G protein coupled receptor activity|class D G-protein coupled receptor activity|class D GPCR activity													molecular_function											owl:Class	
GO:0036318	biolink:NamedThing	peptide pheromone receptor activity	Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity.	got7fsn_ti							bf	2012-08-30T16:45:14Z						molecular_function											owl:Class	
GO:0048204	biolink:NamedThing	vesicle targeting, inter-Golgi cisterna	The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.	got7fsn_ti	inter-Golgi cisterna targeting													biological_process											owl:Class	
GO:0061693	biolink:NamedThing	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity	Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.	got7fsn_ti							dph	2015-05-06T10:04:04Z				MetaCyc:RXN0-6732|EC:2.7.8.37|RHEA:34679		molecular_function											owl:Class	
GO:0009716	biolink:NamedThing	flavonoid phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.	got7fsn_ti	flavonoid phytoalexin biosynthesis|flavonoid phytoalexin synthesis|flavonoid phytoalexin formation|flavonoid phytoalexin anabolism													biological_process											owl:Class	
GO:0052315	biolink:NamedThing	phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response.	got7fsn_ti	phytoalexin biosynthesis													biological_process											owl:Class	
GO:0018658	biolink:NamedThing	salicylate 1-monooxygenase activity	Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2.	got7fsn_ti	salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)|salicylic hydroxylase activity|salicylate hydroxylase activity|salicylate 1-hydroxylase activity|salicylate hydroxylase (decarboxylating)|salicylate monooxygenase activity											RHEA:11004|EC:1.14.13.1|UM-BBD_enzymeID:e0149|MetaCyc:SALICYLATE-1-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0006876	biolink:NamedThing	cellular cadmium ion homeostasis	Any process involved in the maintenance of an internal steady state of cadmium ions at the level of a cell.	got7fsn_ti	cadmium homeostasis													biological_process											owl:Class	
GO:0008109	biolink:NamedThing	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.	got7fsn_ti	uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase|N-acetylglucosaminyltransferase activity|UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase activity|galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase activity|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase activity											MetaCyc:2.4.1.150-RXN|RHEA:17413|EC:2.4.1.150		molecular_function											owl:Class	
GO:0006525	biolink:NamedThing	arginine metabolic process	The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.	got7fsn_ti	arginine metabolism											Wikipedia:Arginine		biological_process											owl:Class	
GO:0009064	biolink:NamedThing	glutamine family amino acid metabolic process	The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.	got7fsn_ti	glutamine family amino acid metabolism													biological_process											owl:Class	
GO:0070824	biolink:NamedThing	SHREC complex	A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.	got7fsn_ti	Snf2/HDAC containing repressor complex|Snf2/Hdac repressive complex	https://github.com/geneontology/go-ontology/issues/20938					mah	2009-07-20T05:02:12Z						cellular_component											owl:Class	
GO:0030476	biolink:NamedThing	ascospore wall assembly	The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	spore wall assembly										GO:0007152			biological_process											owl:Class	
GO:0071940	biolink:NamedThing	fungal-type cell wall assembly	The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall.	got7fsn_ti	fungal-type cell wall formation						mah	2010-09-30T04:59:36Z						biological_process											owl:Class	
GO:0045066	biolink:NamedThing	regulatory T cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types.	got7fsn_ti	regulatory T-lymphocyte differentiation|suppressor T lymphocyte differentiation|suppressor T-cell differentiation|regulatory T lymphocyte differentiation|suppressor T cell differentiation|suppressor T-lymphocyte differentiation|regulatory T-cell differentiation|regulatory T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0036171	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to chemical stimulus	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.	got7fsn_ti							bf	2012-03-27T03:53:28Z						biological_process											owl:Class	
GO:0047453	biolink:NamedThing	ATP-dependent NAD(P)H-hydrate dehydratase activity	Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H(+) + NADH + phosphate.	got7fsn_ti	(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ATP-hydrolysing; NADH-forming)|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ATP-hydrolysing)|ATP-dependent H4NAD(P)OH dehydratase activity|ATP-dependent H(4)NAD(P)OH dehydratase activity|reduced nicotinamide adenine dinucleotide hydrate dehydratase activity											RHEA:19017|KEGG_REACTION:R00129|Reactome:R-HSA-6806967|EC:4.2.1.93|MetaCyc:4.2.1.93-RXN		molecular_function											owl:Class	
GO:0030682	biolink:NamedThing	mitigation of host defenses by symbiont	A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	evasion or tolerance of defense response of other organism during symbiotic interaction|avoidance of defenses of other organism involved in symbiotic interaction|evasion or tolerance of host defense response|evasion or tolerance of defenses of other organism during symbiotic interaction|evasion or tolerance of defenses of other organism|evasion or tolerance of host defenses|evasion or tolerance of defenses of other organism involved in symbiotic interaction|evasion of host defence response|evasion of other organism defence response|avoidance of host defences|evasion or tolerance of defense response of other organism involved in symbiotic interaction|avoidance of defenses of other organism during symbiotic interaction|avoidance of host defenses										GO:0051834|GO:0051832|GO:0051807|GO:0044415|GO:0044413			biological_process											owl:Class	
GO:0061829	biolink:NamedThing	basal tubulobulbar complex	Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell.	got7fsn_ti	basal TBC						dph	2017-01-15T10:42:31Z						cellular_component											owl:Class	
GO:0045861	biolink:NamedThing	negative regulation of proteolysis	Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.	got7fsn_ti	inhibition of proteolysis|negative regulation of peptidolysis|down-regulation of proteolysis|downregulation of proteolysis|down regulation of proteolysis													biological_process											owl:Class	
GO:0032269	biolink:NamedThing	negative regulation of cellular protein metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.	got7fsn_ti	down regulation of cellular protein metabolic process|inhibition of cellular protein metabolic process|negative regulation of cellular protein metabolism|down-regulation of cellular protein metabolic process|downregulation of cellular protein metabolic process													biological_process											owl:Class	
GO:0016157	biolink:NamedThing	sucrose synthase activity	Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose.	got7fsn_ti	uridine diphosphoglucose-fructose glucosyltransferase activity|UDP-glucose-fructose glucosyltransferase activity|sucrose synthetase activity|sucrose-UDP glucosyltransferase activity|UDPglucose-fructose glucosyltransferase activity|sucrose-uridine diphosphate glucosyltransferase activity|NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase activity											EC:2.4.1.13|MetaCyc:SUCROSE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0009087	biolink:NamedThing	methionine catabolic process	The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.	got7fsn_ti	methionine breakdown|methionine catabolism|methionine degradation											UM-BBD_pathwayID:met		biological_process											owl:Class	
GO:0001604	biolink:NamedThing	urotensin II receptor activity	Combining with urotensin II to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0047644	biolink:NamedThing	alizarin 2-beta-glucosyltransferase activity	Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP.	got7fsn_ti	alizarin 2-b-glucosyltransferase activity|UDPglucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyl-transferase activity|uridine diphosphoglucose-alizarin glucosyltransferase activity|UDP-glucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase activity											EC:2.4.1.103|MetaCyc:ALIZARIN-2-BETA-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R03573|RHEA:20677		molecular_function											owl:Class	
GO:0048808	biolink:NamedThing	male genitalia morphogenesis	The process in which the anatomical structures of male genitalia are generated and organized.	got7fsn_ti	male genital morphogenesis													biological_process											owl:Class	
GO:0033037	biolink:NamedThing	polysaccharide localization	Any process in which a polysaccharide is transported to, or maintained in, a specific location.	got7fsn_ti	polysaccharide localisation													biological_process											owl:Class	
GO:0015104	biolink:NamedThing	antimonite transmembrane transporter activity	Enables the transfer of antimonite from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0043624	biolink:NamedThing	cellular protein complex disassembly	The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.	got7fsn_ti														biological_process											owl:Class	
GO:0032984	biolink:NamedThing	protein-containing complex disassembly	The disaggregation of a protein-containing macromolecular complex into its constituent components.	got7fsn_ti	cellular macromolecule complex disassembly|macromolecule complex disassembly|protein complex disassembly										GO:0034623|GO:0043241			biological_process											owl:Class	
GO:0106380	biolink:NamedThing	purine ribonucleotide salvage	Any process which produces a purine ribonucleotide from derivatives of it, without de novo synthesis.	got7fsn_ti							hjd	2021-06-11T14:06:34Z						biological_process											owl:Class	
GO:0033059	biolink:NamedThing	cellular pigmentation	The deposition or aggregation of coloring matter in a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0047919	biolink:NamedThing	GDP-mannose 6-dehydrogenase activity	Catalysis of the reaction: GDP-alpha-D-mannose + H(2)O + 2 NAD(+) = GDP-D-mannuronate + 3 H(+) + 2 NADH.	got7fsn_ti	GDPmannose 6-dehydrogenase activity|guanosine diphospho-D-mannose dehydrogenase activity|GDP-D-mannose:NAD+ 6-oxidoreductase activity|GDP mannose dehydrogenase activity|guanosine diphosphomannose dehydrogenase activity											RHEA:21728|EC:1.1.1.132|KEGG_REACTION:R00880|MetaCyc:GDP-MANNOSE-6-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0050977	biolink:NamedThing	magnetoreception by sensory perception of chemical stimulus	The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli.	got7fsn_ti	magnetoreception, sensory perception of chemical stimulus|magnetoreception by chemical stimulus|magnetoreception, using chemical stimulus|magnetoreception through chemical stimulus													biological_process											owl:Class	
GO:0042799	biolink:NamedThing	histone methyltransferase activity (H4-K20 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein.	got7fsn_ti	histone lysine N-methyltransferase activity (H4-K20 specific)|histone H4 lysine 20-specific methyltransferase activity|histone methylase activity (H4-K20 specific)				Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H4 protein, but that this term still applies.							Reactome:R-HSA-2301205|Reactome:R-HSA-5682965		molecular_function											owl:Class	
GO:0018024	biolink:NamedThing	histone-lysine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.	got7fsn_ti	S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity|protein methyltransferase II activity|histone-lysine N-methylase activity|protein (lysine) methyltransferase activity|protein methylase III activity|S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity|protein methylase 3 activity|histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity											Reactome:R-HSA-5634729|Reactome:R-HSA-5638332|Reactome:R-HSA-5638141|Reactome:R-HSA-5638157|Reactome:R-HSA-3788745|Reactome:R-HSA-5159245|Reactome:R-HSA-5649799|RESID:AA0075|Reactome:R-HSA-5634750|Reactome:R-HSA-5651657|Reactome:R-HSA-5638333|RESID:AA0076|Reactome:R-HSA-4827382|Reactome:R-HSA-5423038|RHEA:10024|Reactome:R-HSA-5244692|Reactome:R-HSA-5637686|EC:2.1.1.354|Reactome:R-HSA-3788748|Reactome:R-HSA-5649800|Reactome:R-HSA-5649801|MetaCyc:HISTONE-LYSINE-N-METHYLTRANSFERASE-RXN|Reactome:R-HSA-4827383|RESID:AA0074|Reactome:R-HSA-5634802|Reactome:R-HSA-5649802|Reactome:R-HSA-5651654|Reactome:R-HSA-5649764		molecular_function											owl:Class	
GO:0046286	biolink:NamedThing	flavonoid phytoalexin catabolic process	The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.	got7fsn_ti	flavonoid phytoalexin degradation|flavonoid phytoalexin catabolism|flavonoid phytoalexin breakdown													biological_process											owl:Class	
GO:0052316	biolink:NamedThing	phytoalexin catabolic process	The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response.	got7fsn_ti	phytoalexin catabolism													biological_process											owl:Class	
GO:0008009	biolink:NamedThing	chemokine activity	The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.	got7fsn_ti														molecular_function											owl:Class	
GO:0005125	biolink:NamedThing	cytokine activity	The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells.	got7fsn_ti	paracrine activity|autocrine activity	https://github.com/geneontology/go-ontology/issues/19116												molecular_function											owl:Class	
GO:0061790	biolink:NamedThing	dense core granule docking	The initial attachment of a dense core granule membrane to the plasma membrane.	got7fsn_ti							dph	2016-09-08T15:51:49Z						biological_process											owl:Class	
GO:0006904	biolink:NamedThing	vesicle docking involved in exocytosis	The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.	got7fsn_ti	vesicle docking during exocytosis													biological_process											owl:Class	
GO:0102484	biolink:NamedThing	esculetin glucosyltransferase activity	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+.	got7fsn_ti												MetaCyc:RXN-14182		molecular_function											owl:Class	
GO:0047655	biolink:NamedThing	allyl-alcohol dehydrogenase activity	Catalysis of the reaction: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH.	got7fsn_ti	allyl-alcohol:NADP+ oxidoreductase activity											RHEA:12168|MetaCyc:ALLYL-ALCOHOL-DEHYDROGENASE-RXN|EC:1.1.1.54|KEGG_REACTION:R03572		molecular_function											owl:Class	
GO:0102794	biolink:NamedThing	cinnamaldehyde:oxygen oxidoreductase activity	Catalysis of the reaction: cinnamaldehyde + O2 + H2O = H+ + trans-cinnamate + hydrogen peroxide.	got7fsn_ti												EC:1.2.3.9|MetaCyc:RXN-8089		molecular_function											owl:Class	
GO:0007476	biolink:NamedThing	imaginal disc-derived wing morphogenesis	The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.	got7fsn_ti	wing morphogenesis													biological_process											owl:Class	
GO:0000213	biolink:NamedThing	tRNA-intron endonuclease activity	Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.	got7fsn_ti	tRNA-intron endoribonuclease activity|splicing endonuclease activity|tRNA splicing endonuclease activity|tRNA-splicing endonuclease activity|transfer ribonucleate intron endoribonuclease activity|transfer splicing endonuclease activity|tRNATRPintron endonuclease activity											MetaCyc:3.1.27.9-RXN|EC:3.1.27.9		molecular_function											owl:Class	
GO:0047863	biolink:NamedThing	dimethylallylcistransferase activity	Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate.	got7fsn_ti	neryl-diphosphate synthase activity|dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase activity											MetaCyc:DIMETHYLALLYLCISTRANSFERASE-RXN|EC:2.5.1.28|KEGG_REACTION:R01659|RHEA:11328		molecular_function											owl:Class	
GO:0002242	biolink:NamedThing	defense response to parasitic plant	Reactions triggered in response to the presence of a parasitic plant that act to protect an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0005981	biolink:NamedThing	regulation of glycogen catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.	got7fsn_ti	regulation of glycogen breakdown|regulation of glycogen catabolism|regulation of glycogen degradation|regulation of glycogenolysis													biological_process											owl:Class	
GO:0032035	biolink:NamedThing	myosin II tail binding	Binding to the tail region of a myosin II heavy chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0032029	biolink:NamedThing	myosin tail binding	Binding to the tail region of a myosin heavy chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0045163	biolink:NamedThing	clustering of voltage-gated potassium channels	The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode.	got7fsn_ti	clustering of voltage-dependent potassium channels|voltage-gated potassium channel clustering|Kv channel clustering|clustering of voltage gated potassium channels													biological_process											owl:Class	
GO:0045161	biolink:NamedThing	neuronal ion channel clustering	The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.	got7fsn_ti														biological_process											owl:Class	
GO:0031162	biolink:NamedThing	sulfur incorporation into metallo-sulfur cluster	The incorporation of exogenous sulfur into a metallo-sulfur cluster.	got7fsn_ti	sulphur incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0033541	biolink:NamedThing	fatty acid beta-oxidation, unsaturated, odd number	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	got7fsn_ti												MetaCyc:PWY-5137		biological_process											owl:Class	
GO:0070763	biolink:NamedThing	Delta1 complex	A protein complex that consists of homodimer of the Notch ligand Delta1.	got7fsn_ti	Delta1 homodimer complex						mah	2009-06-29T01:04:12Z						cellular_component											owl:Class	
GO:0047839	biolink:NamedThing	dATP(dGTP)-DNA purinetransferase activity	Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA.	got7fsn_ti	dATP(dGTP)--DNA purine transferase activity|dATP(dGTP):depurinated-DNA purine transferase activity											MetaCyc:DATPDGTP--DNA-PURINE-TRANSFERASE-RXN|EC:2.6.99.1		molecular_function											owl:Class	
GO:0071726	biolink:NamedThing	cellular response to diacyl bacterial lipopeptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.	got7fsn_ti	cellular response to diacylated bacterial lipoprotein				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:17:02Z						biological_process											owl:Class	
GO:0052741	biolink:NamedThing	(R)-limonene 6-monooxygenase activity	Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+.	got7fsn_ti	(+)-limonene 6-monooxygenase activity|(+)-limonene-6-hydroxylase activity|(R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity											EC:1.14.14.53|RHEA:18957|MetaCyc:1.14.13.84-RXN|KEGG_REACTION:R06119		molecular_function											owl:Class	
GO:0019113	biolink:NamedThing	limonene monooxygenase activity	Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene.	got7fsn_ti												EC:1.14.13.-		molecular_function											owl:Class	
GO:0019966	biolink:NamedThing	interleukin-1 binding	Binding to interleukin-1.	got7fsn_ti	IL-1 binding													molecular_function											owl:Class	
GO:1990516	biolink:NamedThing	ribonucleotide excision repair	The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase.	got7fsn_ti							al	2014-10-14T12:24:37Z						biological_process											owl:Class	
GO:0070716	biolink:NamedThing	mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication	A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.	got7fsn_ti	mismatch repair involved in maintenance of fidelity during DNA-dependent DNA replication						mah	2009-06-09T04:00:29Z						biological_process											owl:Class	
GO:0046232	biolink:NamedThing	carbazole catabolic process	The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.	got7fsn_ti	carbazole breakdown|carbazole catabolism|carbazole degradation													biological_process											owl:Class	
GO:0040027	biolink:NamedThing	negative regulation of vulval development	Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.	got7fsn_ti	downregulation of vulval development|down-regulation of vulval development|down regulation of vulval development|inhibition of vulval development													biological_process											owl:Class	
GO:0061064	biolink:NamedThing	negative regulation of nematode larval development	Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.	got7fsn_ti							dph	2010-03-11T01:04:39Z						biological_process											owl:Class	
GO:0010225	biolink:NamedThing	response to UV-C	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.	got7fsn_ti	response to UVC radiation stimulus|response to shortwave ultraviolet radiation stimulus|response to UV-C light stimulus|response to UV-C radiation stimulus|response to UVC light stimulus|response to germicidal ultraviolet radiation stimulus|response to shortwave ultraviolet light stimulus|response to germicidal ultraviolet light stimulus													biological_process											owl:Class	
GO:0030950	biolink:NamedThing	establishment or maintenance of actin cytoskeleton polarity	Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures.	got7fsn_ti														biological_process											owl:Class	
GO:0009907	biolink:NamedThing	response to photoperiod, red light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm.	got7fsn_ti														biological_process											owl:Class	
GO:0009648	biolink:NamedThing	photoperiodism	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.	got7fsn_ti	response to night length|response to day length|response to photoperiod											Wikipedia:Photoperiodism		biological_process											owl:Class	
GO:1901080	biolink:NamedThing	regulation of relaxation of smooth muscle	Any process that modulates the frequency, rate or extent of relaxation of smooth muscle.	got7fsn_ti	regulation of smooth muscle relaxation						jl	2012-07-04T10:45:09Z						biological_process											owl:Class	
GO:0102682	biolink:NamedThing	N6-(Delta2-isopentenyl)-adenosine 5'-monophosphate phosphoribohydrolase activity	Catalysis of the reaction: N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O <=> N(6)-dimethylallyladenine + D-ribofuranose 5-phosphate.	got7fsn_ti												MetaCyc:RXN-4313|RHEA:48560		molecular_function											owl:Class	
GO:0120196	biolink:NamedThing	negative regulation of anther dehiscence	Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence.	got7fsn_ti							krc	2019-04-09T22:03:16Z						biological_process											owl:Class	
GO:2000241	biolink:NamedThing	regulation of reproductive process	Any process that modulates the frequency, rate or extent of reproductive process.	got7fsn_ti							mah	2010-11-10T02:44:02Z						biological_process											owl:Class	
GO:0072326	biolink:NamedThing	vulval cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.	got7fsn_ti							mah	2010-11-01T02:04:46Z						biological_process											owl:Class	
GO:0003039	biolink:NamedThing	detection of reduced oxygen by carotid body chemoreceptor signaling	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body.	got7fsn_ti	detection of reduced oxygen by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0003020	biolink:NamedThing	detection of reduced oxygen by chemoreceptor signaling	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.	got7fsn_ti	detection of reduced oxygen by chemoreceptor signalling													biological_process											owl:Class	
GO:0005362	biolink:NamedThing	low-affinity glucose:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low-affinity glucose-sodium cotransporter activity											Reactome:R-HSA-429567		molecular_function											owl:Class	
GO:0005412	biolink:NamedThing	glucose:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).	got7fsn_ti	sodium/glucose symporter activity											Reactome:R-HSA-8932955|Reactome:R-HSA-5656356|Reactome:R-HSA-429613|Reactome:R-HSA-5658163|Reactome:R-HSA-189208		molecular_function											owl:Class	
GO:0007212	biolink:NamedThing	dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.	got7fsn_ti	dopamine receptor signalling pathway													biological_process											owl:Class	
GO:0048353	biolink:NamedThing	primary endosperm nucleus	Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac.	got7fsn_ti														cellular_component											owl:Class	
GO:0102377	biolink:NamedThing	steviol 13-O glucosyltransferase activity	Catalysis of the reaction: steviol + UDP-alpha-D-glucose = steviolmonoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13511		molecular_function											owl:Class	
GO:0000321	biolink:NamedThing	re-entry into mitotic cell cycle after pheromone arrest	The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti														biological_process											owl:Class	
GO:0000320	biolink:NamedThing	re-entry into mitotic cell cycle	The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state.	got7fsn_ti														biological_process											owl:Class	
GO:0044172	biolink:NamedThing	host cell endoplasmic reticulum-Golgi intermediate compartment	A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport.	got7fsn_ti	host ER-Golgi intermediate compartment|host cell ER-Golgi intermediate compartment						jl	2009-09-04T02:44:07Z						cellular_component											owl:Class	
GO:0043138	biolink:NamedThing	3'-5' DNA helicase activity	Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent 3'-5' DNA helicase activity|ATP-dependent 3' to 5' DNA helicase activity|3' to 5' DNA helicase activity										GO:0043140	Reactome:R-HSA-9684118|Reactome:R-HSA-167097|Reactome:R-HSA-9613497|Reactome:R-HSA-9613498|Reactome:R-HSA-75949|Reactome:R-HSA-174438|Reactome:R-HSA-9613494|Reactome:R-HSA-9613490		molecular_function											owl:Class	
GO:0003678	biolink:NamedThing	DNA helicase activity	Unwinding of a DNA helix, driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent DNA helicase activity										GO:0003679|GO:0004003	Reactome:R-HSA-5693589|EC:3.6.4.12		molecular_function											owl:Class	
GO:0010145	biolink:NamedThing	fructan metabolic process	The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues.	got7fsn_ti	levan metabolic process|fructan metabolism													biological_process											owl:Class	
GO:0044761	biolink:NamedThing	negative regulation by symbiont of host cholinergic synaptic transmission	Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.	got7fsn_ti							jl	2012-12-06T15:43:53Z						biological_process											owl:Class	
GO:0032223	biolink:NamedThing	negative regulation of synaptic transmission, cholinergic	Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.	got7fsn_ti	downregulation of synaptic transmission, cholinergic|inhibition of synaptic transmission, cholinergic|down regulation of synaptic transmission, cholinergic|down-regulation of synaptic transmission, cholinergic													biological_process											owl:Class	
GO:0061104	biolink:NamedThing	adrenal chromaffin cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.	got7fsn_ti							dph	2010-04-29T08:27:53Z						biological_process											owl:Class	
GO:0010488	biolink:NamedThing	UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.	got7fsn_ti														molecular_function											owl:Class	
GO:0048804	biolink:NamedThing	imaginal disc-derived female genitalia morphogenesis	The process in which the anatomical structures of female genitalia are generated and organized from the genital disc.	got7fsn_ti	female genital morphogenesis													biological_process											owl:Class	
GO:0048807	biolink:NamedThing	female genitalia morphogenesis	The process in which the anatomical structures of female genitalia are generated and organized.	got7fsn_ti	female genital morphogenesis													biological_process											owl:Class	
GO:0018878	biolink:NamedThing	aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen.	got7fsn_ti	aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism													biological_process											owl:Class	
GO:0018877	biolink:NamedThing	beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.	got7fsn_ti	beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism											UM-BBD_pathwayID:hch		biological_process											owl:Class	
GO:0031366	biolink:NamedThing	N-terminal peptidyl-asparagine deamination	The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0031364	biolink:NamedThing	N-terminal protein amino acid deamination, from side chain	The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0098571	biolink:NamedThing	lumenal side of plastid thylakoid membrane	The side (leaflet) of the plastid thylakoid membrane that faces the lumen, and any proteins embedded in it or loosely bound to its surface.	got7fsn_ti														cellular_component											owl:Class	
GO:0071228	biolink:NamedThing	cellular response to tumor cell	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.	got7fsn_ti							mah	2009-12-03T02:04:43Z						biological_process											owl:Class	
GO:0106176	biolink:NamedThing	clathrin-coated endocytic vesicle lumen	The volume enclosed by the membrane of a clathrin-coated endocytic vesicle.	got7fsn_ti							hjd	2019-02-12T15:44:51Z						cellular_component											owl:Class	
GO:0071682	biolink:NamedThing	endocytic vesicle lumen	The volume enclosed by the membrane of an endocytic vesicle.	got7fsn_ti							mah	2010-02-18T04:21:53Z						cellular_component											owl:Class	
GO:0015948	biolink:NamedThing	methanogenesis	The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.	got7fsn_ti	methane biosynthesis|methane biosynthetic process											Wikipedia:Methanogenesis|UM-BBD_pathwayID:meth		biological_process											owl:Class	
GO:0034417	biolink:NamedThing	bisphosphoglycerate 3-phosphatase activity	Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phospho-D-glycerate + phosphate.	got7fsn_ti	2,3-bisphospho-D-glycerate 3-phosphohydrolase activity											MetaCyc:RXN-11102|RHEA:27381|KEGG_REACTION:R09532|EC:3.1.3.80		molecular_function											owl:Class	
GO:0034416	biolink:NamedThing	bisphosphoglycerate phosphatase activity	Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = phosphoglycerate + phosphate.	got7fsn_ti	2,3-diphosphoglycerate phosphatase activity|diphosphoglycerate phosphatase activity|glycerate-2,3-diphosphate phosphatase activity|2,3-bisphosphoglycerate phosphatase activity|2,3-diphosphoglyceric acid phosphatase activity													molecular_function											owl:Class	
GO:0102882	biolink:NamedThing	beta-acoradiene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-acoradiene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8423		molecular_function											owl:Class	
GO:0032972	biolink:NamedThing	regulation of muscle filament sliding speed	Any process that modulates the velocity of muscle filament sliding.	got7fsn_ti														biological_process											owl:Class	
GO:0032971	biolink:NamedThing	regulation of muscle filament sliding	Any process that modulates the frequency, rate or extent of muscle filament sliding.	got7fsn_ti														biological_process											owl:Class	
GO:0102697	biolink:NamedThing	trans-zeatin-O-glucoside UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + O-beta-D-glucosyl-trans-zeatin = H+ + trans-zeatin-O-glucoside-7-N-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-4736		molecular_function											owl:Class	
GO:0005640	biolink:NamedThing	nuclear outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.	got7fsn_ti	nucleus outer envelope|perinuclear membrane											NIF_Subcellular:sao1617136075		cellular_component											owl:Class	
GO:0031965	biolink:NamedThing	nuclear membrane	Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.	got7fsn_ti												NIF_Subcellular:sao1687101204		cellular_component											owl:Class	
GO:0098754	biolink:NamedThing	detoxification	Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.	got7fsn_ti														biological_process											owl:Class	
GO:0006429	biolink:NamedThing	leucyl-tRNA aminoacylation	The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0009541	biolink:NamedThing	etioplast prolamellar body	A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast.	got7fsn_ti														cellular_component											owl:Class	
GO:0035621	biolink:NamedThing	ER to Golgi ceramide transport	The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.	got7fsn_ti	non-vesicular ceramide trafficking|ER to Golgi ceramide translocation|endoplasmic reticulum to Golgi ceramide transport						bf	2010-12-08T12:36:35Z						biological_process											owl:Class	
GO:0032365	biolink:NamedThing	intracellular lipid transport	The directed movement of lipids within cells.	got7fsn_ti														biological_process											owl:Class	
GO:0003101	biolink:NamedThing	regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine	The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system.	got7fsn_ti	regulation of blood pressure by circulating adrenaline-noradrenaline													biological_process											owl:Class	
GO:0046064	biolink:NamedThing	dCMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate.	got7fsn_ti	dCMP anabolism|dCMP biosynthesis|dCMP synthesis|dCMP formation													biological_process											owl:Class	
GO:0042042	biolink:NamedThing	tungsten incorporation into tungsten-molybdopterin complex	The incorporation of tungsten into a tungsten-molybdopterin complex.	got7fsn_ti														biological_process											owl:Class	
GO:0042040	biolink:NamedThing	metal incorporation into metallo-molybdopterin complex	The incorporation of a metal into a metallo-molybdopterin complex.	got7fsn_ti														biological_process											owl:Class	
GO:0047807	biolink:NamedThing	cytokinin 7-beta-glucosyltransferase activity	Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.	got7fsn_ti	cytokinin 7-glucosyltransferase activity|uridine diphosphoglucose-zeatin 7-glucosyltransferase activity|cytokinin 7-b-glucosyltransferase activity|UDP-glucose:zeatin 7-glucosyltransferase activity|UDP-glucose-zeatin 7-glucosyltransferase activity|UDPglucose:zeatin 7-glucosyltransferase activity											EC:2.4.1.118|KEGG_REACTION:R04071|RHEA:23272|MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0018766	biolink:NamedThing	dihydrophloroglucinol hydrolase activity	Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate.	got7fsn_ti												UM-BBD_reactionID:r0008|MetaCyc:R6-RXN|KEGG_REACTION:R07831		molecular_function											owl:Class	
GO:0034815	biolink:NamedThing	cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity	Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+.	got7fsn_ti												EC:4.1.3.-|UM-BBD_reactionID:r1135		molecular_function											owl:Class	
GO:0019185	biolink:NamedThing	snRNA-activating protein complex	A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.	got7fsn_ti	SNAPc													cellular_component											owl:Class	
GO:0051738	biolink:NamedThing	xanthophyll binding	Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen.	got7fsn_ti														molecular_function											owl:Class	
GO:0021771	biolink:NamedThing	lateral geniculate nucleus development	The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina.	got7fsn_ti	LGN development													biological_process											owl:Class	
GO:0031729	biolink:NamedThing	CCR4 chemokine receptor binding	Binding to a CCR4 chemokine receptor.	got7fsn_ti	CCR4 chemokine receptor ligand													molecular_function											owl:Class	
GO:0071752	biolink:NamedThing	secretory dimeric IgA immunoglobulin complex	A dimeric form of secretory IgA immunoglobulin complex.	got7fsn_ti	secretory dimeric IgA antibody|secretory dimeric IgA1 antibody				Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0071751	biolink:NamedThing	secretory IgA immunoglobulin complex	A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.	got7fsn_ti	sIgA antibody|secretory IgA antibody|sIgA1 antibody				Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0047014	biolink:NamedThing	glycerol-3-phosphate 1-dehydrogenase [NADP+] activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + H(+) + NADPH.	got7fsn_ti	NADPH-dependent glycerin-3-phosphate dehydrogenase activity|glycerin-3-phosphate dehydrogenase activity|L-glycerol 3-phosphate:NADP oxidoreductase activity|sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase activity|glycerol phosphate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity											MetaCyc:1.1.1.177-RXN|KEGG_REACTION:R00845|EC:1.1.1.177|RHEA:19773		molecular_function											owl:Class	
GO:0045002	biolink:NamedThing	double-strand break repair via single-strand annealing	Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats.	got7fsn_ti														biological_process											owl:Class	
GO:0102974	biolink:NamedThing	hydroxyversicolorone reductase activity	Catalysis of the reaction: versicolorone + NADP = hydroxyversicolorone + NADPH.	got7fsn_ti												MetaCyc:RXN-9489|RHEA:35691|EC:1.1.1.353		molecular_function											owl:Class	
GO:0010138	biolink:NamedThing	pyrimidine ribonucleotide salvage	The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.	got7fsn_ti												MetaCyc:PWY0-163		biological_process											owl:Class	
GO:0071983	biolink:NamedThing	exit from reproductive diapause	The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	got7fsn_ti							mah	2010-10-21T04:48:12Z						biological_process											owl:Class	
GO:0071981	biolink:NamedThing	exit from diapause	The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.	got7fsn_ti							mah	2010-10-21T04:45:40Z						biological_process											owl:Class	
GO:1990660	biolink:NamedThing	calprotectin complex	A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of toll-like receptor 4 (TLR4) and of the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways.	got7fsn_ti	calprotectin heterodimer				An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T14:03:17Z						cellular_component											owl:Class	
GO:0048456	biolink:NamedThing	stamen structural organization	The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	stamen structural organisation										GO:0048428			biological_process											owl:Class	
GO:0045008	biolink:NamedThing	depyrimidination	The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar.	got7fsn_ti														biological_process											owl:Class	
GO:0006285	biolink:NamedThing	base-excision repair, AP site formation	The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.	got7fsn_ti														biological_process											owl:Class	
GO:0052603	biolink:NamedThing	1-chloro-4-nitrosobenzene nitroreductase activity	Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O.	got7fsn_ti												UM-BBD_enzymeID:e0245|MetaCyc:RXN-8834		molecular_function											owl:Class	
GO:0060432	biolink:NamedThing	lung pattern specification process	Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate.	got7fsn_ti														biological_process											owl:Class	
GO:0016049	biolink:NamedThing	cell growth	The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.	got7fsn_ti	non-developmental growth of a unicellular organism|metabolic process resulting in cell growth|cellular growth|non-developmental cell growth|metabolism resulting in cell growth|cell expansion|growth of cell										GO:0048591			biological_process											owl:Class	
GO:0009828	biolink:NamedThing	plant-type cell wall loosening	The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana.	got7fsn_ti	cellulose and pectin-containing cell wall loosening													biological_process											owl:Class	
GO:0009827	biolink:NamedThing	plant-type cell wall modification	The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana.	got7fsn_ti	cellulose and pectin-containing cell wall modification													biological_process											owl:Class	
GO:0008502	biolink:NamedThing	melatonin receptor activity	Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.	got7fsn_ti														molecular_function											owl:Class	
GO:0036132	biolink:NamedThing	13-prostaglandin reductase activity	Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin.	got7fsn_ti	prostaglandin delta13-reductase activity|15-oxo-delta13-prostaglandin reductase activity|15-ketoprostaglandin delta13-reductase activity|delta13-15-ketoprostaglandin reductase activity|prostaglandin 13-reductase activity|15-oxoprostaglandin 13-reductase activity				Note that this is the reverse of the reaction described in '15-oxoprostaglandin 13-oxidase activity ; GO:0047522'.		bf	2012-03-05T10:42:22Z				EC:1.3.1.48|KEGG_REACTION:R04556|Reactome:R-HSA-2161692|KEGG_REACTION:R04557		molecular_function											owl:Class	
GO:0001806	biolink:NamedThing	type IV hypersensitivity	An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.	got7fsn_ti	delayed hypersensitivity response|delayed-type hypersensitivity										GO:0016069	Wikipedia:Type_IV_hypersensitivity		biological_process											owl:Class	
GO:0001163	biolink:NamedThing	RNA polymerase I transcription regulatory region sequence-specific DNA binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.	got7fsn_ti	RNA polymerase I regulatory region DNA binding	https://github.com/geneontology/go-ontology/issues/19312					krc	2011-01-31T04:12:06Z			GO:0001013			molecular_function											owl:Class	
GO:0034713	biolink:NamedThing	type I transforming growth factor beta receptor binding	Binding to a type I transforming growth factor beta receptor.	got7fsn_ti	babo binding|transforming growth factor beta receptor type I binding|sax binding|tkv binding|saxophone ligand|transforming growth factor beta ligand binding to type I receptor|sax ligand|babo ligand|thickveins binding|tkv ligand|TGF-beta type I binding|thickveins ligand|type I TGF-beta binding|baboon binding|saxophone binding|baboon receptor ligand|baboon ligand										GO:0005103|GO:0005116|GO:0005120			molecular_function											owl:Class	
GO:0102508	biolink:NamedThing	cyanidin 3,7-diglucoside glucosidase activity	Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-14435		molecular_function											owl:Class	
GO:0046925	biolink:NamedThing	peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine	The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine.	got7fsn_ti												RESID:AA0341		biological_process											owl:Class	
GO:0022017	biolink:NamedThing	neuroblast division in pallium	The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0021873	biolink:NamedThing	forebrain neuroblast division	The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.	got7fsn_ti														biological_process											owl:Class	
GO:0035270	biolink:NamedThing	endocrine system development	Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.	got7fsn_ti														biological_process											owl:Class	
GO:0062154	biolink:NamedThing	N6-mAMP deaminase activity	Catalysis of the reaction: H(+) + H2O + N6-methyl-AMP = IMP + methylamine.	got7fsn_ti	MAPDA						dph	2019-09-20T13:16:37Z				RHEA:16001		molecular_function											owl:Class	
GO:0034054	biolink:NamedThing	suppression by symbiont of host defense-related programmed cell death	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition of hypersensitive response|negative regulation by symbiont of plant HR|negative regulation by symbiont of plant hypersensitive response|negative regulation by symbiont of host defense-related programmed cell death|down-regulation by symbiont of host defense-related programmed cell death|down regulation by symbiont of host defense-related programmed cell death|inhibition of HR|negative regulation by symbiont of host defense-related PCD|inhibition by symbiont of host defense-related PCD|inhibition by symbiont of host defense-related programmed cell death|downregulation by symbiont of host defense-related programmed cell death|inhibition of host defense-related PCD|suppression by symbiont of host defense-related programmed cell death|suppression of HR				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of plant-type hypersensitive response ; GO:0034051'.									biological_process											owl:Class	
GO:0052041	biolink:NamedThing	negative regulation by symbiont of host programmed cell death	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition of host programmed cell death|down-regulation by symbiont of host programmed cell death|inhibition by symbiont of host programmed cell death|suppression by symbiont of host programmed cell death|down regulation by symbiont of host programmed cell death|suppression by symbiont of host PCD|downregulation by symbiont of host programmed cell death													biological_process											owl:Class	
GO:0048912	biolink:NamedThing	glial cell migration in anterior lateral line nerve	The movement of a glial cell along the axons in the anterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0048896	biolink:NamedThing	lateral line nerve glial cell migration	The movement of a glial cell along the axons in a lateral line nerve.	got7fsn_ti	glial cell migration in lateral line nerve													biological_process											owl:Class	
GO:0000992	biolink:NamedThing	RNA polymerase III cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes.	got7fsn_ti							krc	2010-08-11T03:49:28Z						molecular_function											owl:Class	
GO:0047646	biolink:NamedThing	alkanal monooxygenase (FMN-linked) activity	Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light.	got7fsn_ti	aldehyde monooxygenase activity|bacterial luciferase activity|vibrio fischeri luciferase activity|alkanal,reduced-FMN:oxygen oxidoreductase (1-hydroxylating, luminescing)											RHEA:17181|EC:1.14.14.3|MetaCyc:ALKANAL-MONOOXYGENASE-FMN-LINKED-RXN		molecular_function											owl:Class	
GO:0140303	biolink:NamedThing	intramembrane lipid transporter activity	Enables the transport of a lipid from a region of a membrane to a different region on the same membrane.	got7fsn_ti	flippase activity|translocase activity	https://github.com/geneontology/go-ontology/issues/19477|https://github.com/geneontology/go-ontology/issues/17648					pg	2019-03-01T20:14:09Z						molecular_function											owl:Class	
GO:0005319	biolink:NamedThing	lipid transporter activity	Enables the directed movement of lipids into, out of or within a cell, or between cells.	got7fsn_ti	apolipoprotein|lipophorin											Reactome:R-HSA-5688397|Reactome:R-HSA-8848053|Reactome:R-HSA-5683672|Reactome:R-HSA-174786|Reactome:R-HSA-1369028|Reactome:R-HSA-8866329|Reactome:R-HSA-5682285|Reactome:R-HSA-5682311|Reactome:R-HSA-5683714|Reactome:R-HSA-6801250|Reactome:R-HSA-1369052		molecular_function											owl:Class	
GO:0099637	biolink:NamedThing	neurotransmitter receptor transport	The directed movement of neurotransmitter receptors.	got7fsn_ti														biological_process											owl:Class	
GO:0045578	biolink:NamedThing	negative regulation of B cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.	got7fsn_ti	down-regulation of B cell differentiation|down regulation of B cell differentiation|negative regulation of B cell development|inhibition of B cell differentiation|negative regulation of B lymphocyte differentiation|downregulation of B cell differentiation|negative regulation of B-cell differentiation|negative regulation of B-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0045620	biolink:NamedThing	negative regulation of lymphocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.	got7fsn_ti	negative regulation of lymphocyte development|inhibition of lymphocyte differentiation|down regulation of lymphocyte differentiation|downregulation of lymphocyte differentiation|down-regulation of lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0036011	biolink:NamedThing	imaginal disc-derived leg segmentation	Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint.	got7fsn_ti							bf	2011-10-07T04:37:17Z						biological_process											owl:Class	
GO:0035285	biolink:NamedThing	appendage segmentation	Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.	got7fsn_ti														biological_process											owl:Class	
GO:0021660	biolink:NamedThing	rhombomere 3 formation	The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0021594	biolink:NamedThing	rhombomere formation	The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.	got7fsn_ti														biological_process											owl:Class	
GO:0021655	biolink:NamedThing	rhombomere 2 morphogenesis	The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0042023	biolink:NamedThing	DNA endoreduplication	Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.	got7fsn_ti	DNA endoreplication|DNA re-duplication				Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states.									biological_process											owl:Class	
GO:0009448	biolink:NamedThing	gamma-aminobutyric acid metabolic process	The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.	got7fsn_ti	gamma-aminobutyric acid metabolism|4-aminobutyrate metabolism|4-aminobutanoate metabolism|4-aminobutyrate metabolic process|4-aminobutanoate metabolic process|GABA metabolism|GABA metabolic process				See also the biological process term 'neurotransmitter metabolic process ; GO:0042133'.									biological_process											owl:Class	
GO:0030117	biolink:NamedThing	membrane coat	Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules.	got7fsn_ti														cellular_component											owl:Class	
GO:0060603	biolink:NamedThing	mammary gland duct morphogenesis	The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.	got7fsn_ti							dph	2009-05-15T09:22:25Z						biological_process											owl:Class	
GO:0001991	biolink:NamedThing	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen.	got7fsn_ti	control of blood pressure by circulatory renin-angiotensin|renin-angiotensin blood pressure control|circulatory renin-angiotensin regulation of blood pressure|circulatory renin-angiotensin blood pressure regulation|circulatory renin-angiotensin control of blood pressure													biological_process											owl:Class	
GO:0046937	biolink:NamedThing	phytochelatin metabolic process	The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.	got7fsn_ti	phytochelatin metabolism|cadystin metabolism|cadystin metabolic process													biological_process											owl:Class	
GO:0002385	biolink:NamedThing	mucosal immune response	An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.	got7fsn_ti	immune response in mucosal-associated lymphoid tissue|immune response in MALT|immune response in urogenital tract										GO:0002422|GO:0002386			biological_process											owl:Class	
GO:0030773	biolink:NamedThing	6-hydroxymellein O-methyltransferase activity	Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	6-hydroxymellein methyltransferase activity|S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase activity											MetaCyc:6-HYDROXYMELLEIN-O-METHYLTRANSFERASE-RXN|KEGG_REACTION:R03934|RHEA:15201|EC:2.1.1.108		molecular_function											owl:Class	
GO:0042932	biolink:NamedThing	chrysobactin transport	The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0070612	biolink:NamedThing	histone methyltransferase activity (H2A-R3 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A.	got7fsn_ti	histone-arginine N-methyltransferase activity (H2A-R3 specific)|histone methylase activity (H2A-R3 specific)						mah	2009-04-29T02:06:45Z						molecular_function											owl:Class	
GO:0047520	biolink:NamedThing	11-cis-retinyl-palmitate hydrolase activity	Catalysis of the reaction: 11-cis-retinyl palmitate + H(2)O = 11-cis-retinol + H(+) + palmitate.	got7fsn_ti	RPH|11-cis-retinol palmitate esterase activity|11-cis-retinyl-palmitate acylhydrolase activity											KEGG_REACTION:R03049|RHEA:19697|MetaCyc:11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN|Reactome:R-HSA-2465941|EC:3.1.1.63		molecular_function											owl:Class	
GO:0043853	biolink:NamedThing	methanol-CoM methyltransferase complex	A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol.	got7fsn_ti	methanol: CoM methyltransferase complex|methanol-coenzyme M methyltransferase complex|methanol:coenzyme M methyltransferase complex|methanol: coenzyme M methyltransferase complex|methanol:CoM methyltransferase complex											MetaCyc:CPLX-421		cellular_component											owl:Class	
GO:0031753	biolink:NamedThing	endothelial differentiation G protein-coupled receptor binding	Binding to an endothelial differentiation G protein-coupled receptor.	got7fsn_ti	endothelial differentiation G-protein coupled receptor binding|endothelial differentiation G-protein coupled receptor ligand													molecular_function											owl:Class	
GO:0005267	biolink:NamedThing	potassium channel activity	Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti												Reactome:R-HSA-1299304|Reactome:R-HSA-1296039|Reactome:R-HSA-1299359|Reactome:R-HSA-1296037|Reactome:R-HSA-1299297|Reactome:R-HSA-1296348|Reactome:R-HSA-1299338|Reactome:R-HSA-1299318|Reactome:R-HSA-1296035|Reactome:R-HSA-2534365|Reactome:R-HSA-5578910|Reactome:R-HSA-1296024		molecular_function											owl:Class	
GO:0102551	biolink:NamedThing	homogentisate geranylgeranyl transferase activity	Catalysis of the reaction: 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + homogentisate + H+ <=> diphosphoric acid + 2-methyl-6-geranylgeranyl-1,4-benzoquinol + carbon dioxide.	got7fsn_ti												RHEA:38003|EC:2.5.1.116|MetaCyc:RXN-14929		molecular_function											owl:Class	
GO:0070045	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-2 complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof).	got7fsn_ti	Stx2-Snap25-Vamp2 complex|SNARE complex (Stx2, Snap25, Vamp2)													cellular_component											owl:Class	
GO:0019879	biolink:NamedThing	peptidyl-thyronine biosynthetic process from peptidyl-tyrosine	The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine.	got7fsn_ti	peptidyl-thyronine synthesis from peptidyl-tyrosine|peptidyl-thyronine anabolism from peptidyl-tyrosine|peptidyl-thyronine formation from peptidyl-tyrosine				See also the biological process term 'peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine ; GO:0018250'.									biological_process											owl:Class	
GO:0022031	biolink:NamedThing	telencephalon astrocyte cell migration	The orderly movement of an astrocyte cell through the telencephalon.	got7fsn_ti														biological_process											owl:Class	
GO:0043615	biolink:NamedThing	astrocyte cell migration	The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.	got7fsn_ti	astrocytic glial cell migration|astrocyte migration													biological_process											owl:Class	
GO:0102656	biolink:NamedThing	1-18:2-2-trans-16:1-phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-1727		molecular_function											owl:Class	
GO:0060228	biolink:NamedThing	phosphatidylcholine-sterol O-acyltransferase activator activity	Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.	got7fsn_ti	LCAT activator activity													molecular_function											owl:Class	
GO:0086022	biolink:NamedThing	SA node cell-atrial cardiac muscle cell adhesion involved in cell communication	The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	got7fsn_ti	SA cardiac muscle cell-atrial cardiac muscle cell adhesion involved in cell communication|SA cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|sinus node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|sinoatrial node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SAN cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication						tb	2011-11-10T09:26:52Z						biological_process											owl:Class	
GO:0004319	biolink:NamedThing	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+.	got7fsn_ti	enoyl-acyl-carrier-protein reductase (NADPH2, B-specific)|enoyl acyl-carrier-protein reductase activity|enoyl-acyl-carrier-protein reductase (NADPH, B-specific)|acyl-acyl-carrier-protein:NADP+ oxidoreductase (B-specific)|enoyl-ACP reductase (NADPH, B-specific) activity|reductase, enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate)|enoyl-[acyl-carrier protein] reductase (NADPH, B-specific) activity|NADPH 2-enoyl Co A reductase activity											EC:1.3.1.10|MetaCyc:ENOYL-ACP-REDUCT-NADPH-RXN		molecular_function											owl:Class	
GO:0031931	biolink:NamedThing	TORC1 complex	A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.	got7fsn_ti	TORC1|mTORC1|dTORC1|rapamycin and nutrient-sensitive TOR complex|dTOR/dRaptor complex|TORC 1 complex|nutrient sensitive complex|TOR complex 1											Wikipedia:MTORC1		cellular_component											owl:Class	
GO:0033887	biolink:NamedThing	chondro-4-sulfatase activity	Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.	got7fsn_ti	4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity											RHEA:11444|KEGG_REACTION:R03517|EC:3.1.6.9|MetaCyc:CHONDRO-4-SULFATASE-RXN		molecular_function											owl:Class	
GO:0120159	biolink:NamedThing	rRNA pseudouridine synthase activity	Catalysis of the reaction: an rRNA uridine = an rRNA pseudouridine. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.	got7fsn_ti	16S rRNA pseudouridine(516) synthase|21S rRNA pseudouridine(2819) synthase|23S rRNA pseudouridine(955/2504/2580) synthase|23S rRNA pseudouridine(2604) synthase|23S rRNA pseudouridine(2457) synthase|23S rRNA pseudouridine(1911/1915/1917) synthase|23S rRNA pseudouridine(746) synthase|23S rRNA pseudouridine(2605) synthase						krc	2018-05-11T21:24:19Z				EC:5.4.99.24|EC:5.4.99.23|EC:5.4.99.20|EC:5.4.99.19|EC:5.4.99.21|EC:5.4.99.22|EC:5.4.99.29|EC:5.4.99.43		molecular_function											owl:Class	
GO:0018593	biolink:NamedThing	4-chlorophenoxyacetate monooxygenase activity	Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol.	got7fsn_ti												UM-BBD_reactionID:r0281		molecular_function											owl:Class	
GO:0099401	biolink:NamedThing	caveola bulb	The region of a caveola that extends into the cytoplasm, excluding the neck (rim).  This region is associated with intracellular caveola proteins.	got7fsn_ti	caveola crater													cellular_component											owl:Class	
GO:0033947	biolink:NamedThing	mannosylglycoprotein endo-beta-mannosidase activity	Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.	got7fsn_ti	endo-beta-mannosidase activity											MetaCyc:3.2.1.152-RXN|EC:3.2.1.152		molecular_function											owl:Class	
GO:0039010	biolink:NamedThing	specification of pronephric distal tubule identity	The process in which the distal tubule of the pronephric nephron acquires its identity.	got7fsn_ti							bf	2010-07-02T09:51:28Z						biological_process											owl:Class	
GO:1990420	biolink:NamedThing	establishment of septation initiation network asymmetry	The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies.	got7fsn_ti	establishment of SIN asymmetry						al	2014-07-16T13:51:36Z						biological_process											owl:Class	
GO:0031028	biolink:NamedThing	septation initiation signaling	The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.	got7fsn_ti	septation initiation signalling|SIN|septation initiation signaling cascade|septation initiation network													biological_process											owl:Class	
GO:0004873	biolink:NamedThing	asialoglycoprotein receptor activity	Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane.	got7fsn_ti														molecular_function											owl:Class	
GO:0090490	biolink:NamedThing	L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)	Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O.	got7fsn_ti							tb	2012-10-16T16:27:19Z						molecular_function											owl:Class	
GO:0030661	biolink:NamedThing	chitosome membrane	The lipid bilayer surrounding a chitosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0004742	biolink:NamedThing	dihydrolipoyllysine-residue acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide.	got7fsn_ti	acetyl-CoA: enzyme-N6-(dihydrolipoyl)lysine S-acetyltransferase activity|lipoate transacetylase activity|transacetylase X activity|enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase activity|dihydrolipoamide S-acetyltransferase activity|lipoylacetyltransferase activity|dihydrolipoic transacetylase activity|dihydrolipoate acetyltransferase activity|lipoic acid acetyltransferase activity|lipoate acetyltransferase activity|lipoic acetyltransferase activity|thioltransacetylase A activity|lipoic transacetylase activity|acetyl-CoA:dihydrolipoamide S-acetyltransferase activity|dihydrolipoyl acetyltransferase activity|acetyl-CoA: enzyme-6-N-(dihydrolipoyl)lysine S-acetyltransferase activity											EC:2.3.1.12		molecular_function											owl:Class	
GO:0032050	biolink:NamedThing	clathrin heavy chain binding	Binding to a clathrin heavy chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0030276	biolink:NamedThing	clathrin binding	Binding to a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.	got7fsn_ti														molecular_function											owl:Class	
GO:0033212	biolink:NamedThing	iron import into cell	The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.	got7fsn_ti	iron assimilation|ferrous iron uptake|ferrous ion import|ferrous iron import						mah	2009-05-01T04:19:14Z			GO:0070627			biological_process											owl:Class	
GO:0006879	biolink:NamedThing	cellular iron ion homeostasis	Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.	got7fsn_ti	iron homeostasis													biological_process											owl:Class	
GO:0071485	biolink:NamedThing	cellular response to absence of light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.	got7fsn_ti	cellular response to darkness						mah	2009-12-18T02:13:12Z						biological_process											owl:Class	
GO:0031325	biolink:NamedThing	positive regulation of cellular metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.	got7fsn_ti	upregulation of cellular metabolic process|stimulation of cellular metabolic process|activation of cellular metabolic process|up regulation of cellular metabolic process|positive regulation of cellular metabolism|up-regulation of cellular metabolic process													biological_process											owl:Class	
GO:0002757	biolink:NamedThing	immune response-activating signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response.	got7fsn_ti														biological_process											owl:Class	
GO:0050579	biolink:NamedThing	vellosimine dehydrogenase activity	Catalysis of the reaction: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine.	got7fsn_ti	10-deoxysarpagine:NADP+ oxidoreductase activity											MetaCyc:1.1.1.273-RXN|RHEA:20029|KEGG_REACTION:R05827|EC:1.1.1.273		molecular_function											owl:Class	
GO:0102875	biolink:NamedThing	1-18:2-2-18:2-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-18:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8366|EC:1.14.19.35		molecular_function											owl:Class	
GO:0050671	biolink:NamedThing	positive regulation of lymphocyte proliferation	Any process that activates or increases the rate or extent of lymphocyte proliferation.	got7fsn_ti	up-regulation of lymphocyte proliferation|stimulation of lymphocyte proliferation|activation of lymphocyte proliferation|up regulation of lymphocyte proliferation|upregulation of lymphocyte proliferation													biological_process											owl:Class	
GO:0032946	biolink:NamedThing	positive regulation of mononuclear cell proliferation	Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.	got7fsn_ti	stimulation of mononuclear cell proliferation|activation of mononuclear cell proliferation|up regulation of mononuclear cell proliferation|positive regulation of peripheral blood mononuclear cell proliferation|positive regulation of PBMC proliferation|upregulation of mononuclear cell proliferation|up-regulation of mononuclear cell proliferation													biological_process											owl:Class	
GO:0050203	biolink:NamedThing	oxalate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA.	got7fsn_ti	oxalyl-CoA synthetase activity|oxalyl coenzyme A synthetase activity|oxalate:CoA ligase (AMP-forming)											MetaCyc:OXALATE--COA-LIGASE-RXN|RHEA:18293|EC:6.2.1.8|KEGG_REACTION:R01558		molecular_function											owl:Class	
GO:0140614	biolink:NamedThing	1,8-dihydroxynaphthalene-melanin biosynthetic process	The chemical reactions and pathways resulting in the formation of dihydroxy naphthalene (DHN)-melanin.	got7fsn_ti	DHN-melanin biosynthesis	https://github.com/geneontology/go-ontology/issues/20974					pg	2021-03-04T11:54:05Z						biological_process											owl:Class	
GO:0052828	biolink:NamedThing	inositol-3,4-bisphosphate 4-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate.	got7fsn_ti							ai	2011-11-29T09:57:00Z				RHEA:43388|Reactome:R-HSA-1855202		molecular_function											owl:Class	
GO:0016312	biolink:NamedThing	inositol bisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate.	got7fsn_ti												RHEA:57840|Reactome:R-HSA-6809565|Reactome:R-HSA-6809561		molecular_function											owl:Class	
GO:0031580	biolink:NamedThing	membrane raft distribution	The process that establishes the spatial arrangement of membrane rafts within a cellular membrane.	got7fsn_ti	lipid raft distribution													biological_process											owl:Class	
GO:0044535	biolink:NamedThing	very-long-chain fatty acyl-CoA oxidase activity	Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.	got7fsn_ti	very-long-chain acyl-CoA oxidase activity|very long chain fatty-acyl-CoA oxidase activity|VLC fatty-acyl-CoA oxidase activity						jl	2012-03-21T02:04:42Z				EC:1.3.3.-		molecular_function											owl:Class	
GO:0022619	biolink:NamedThing	generative cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte.	got7fsn_ti														biological_process											owl:Class	
GO:0016160	biolink:NamedThing	amylase activity	Catalysis of the hydrolysis of amylose or an amylose derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0019646	biolink:NamedThing	aerobic electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.	got7fsn_ti	ubiquinone-8-O2 electron transport|succinate-O2 electron transport|NADH-O2 electron transport										GO:0006137|GO:0006138|GO:0006136			biological_process											owl:Class	
GO:0018359	biolink:NamedThing	protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine	The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine.	got7fsn_ti	protein-haem P460 linkage via haem P460-bis-L-cysteine-L-tyrosine										GO:0018385	RESID:AA0266		biological_process											owl:Class	
GO:0014853	biolink:NamedThing	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	got7fsn_ti	regulation of excitatory post-synaptic membrane potential involved in skeletal muscle contraction													biological_process											owl:Class	
GO:0098815	biolink:NamedThing	modulation of excitatory postsynaptic potential	Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	got7fsn_ti														biological_process											owl:Class	
GO:0110011	biolink:NamedThing	regulation of basement membrane organization	Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.	got7fsn_ti							kmv							biological_process											owl:Class	
GO:0120117	biolink:NamedThing	T cell meandering migration	The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs).	got7fsn_ti	T cell meandering search|lymph node surveillance						krc	2017-11-22T18:13:01Z						biological_process											owl:Class	
GO:1990006	biolink:NamedThing	amorphous vesicle	A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway.	got7fsn_ti							pr	2012-12-11T14:55:36Z				NIF_Subcellular:sao1531915298		cellular_component											owl:Class	
GO:0010160	biolink:NamedThing	formation of animal organ boundary	The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.	got7fsn_ti	organ boundary specification										GO:0048862			biological_process											owl:Class	
GO:0015929	biolink:NamedThing	hexosaminidase activity	Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.	got7fsn_ti												MetaCyc:3.2.1.52-RXN		molecular_function											owl:Class	
GO:0090369	biolink:NamedThing	ornithine carbamoyltransferase inhibitor activity	Binds to and stops, prevents, or reduces the activity of ornithine carbamoyltransferase.	got7fsn_ti							tb	2010-07-12T11:19:55Z						molecular_function											owl:Class	
GO:0022416	biolink:NamedThing	chaeta development	The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.	got7fsn_ti	bristle development													biological_process											owl:Class	
GO:0014730	biolink:NamedThing	skeletal muscle regeneration at neuromuscular junction	The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers.	got7fsn_ti														biological_process											owl:Class	
GO:0043403	biolink:NamedThing	skeletal muscle tissue regeneration	The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.	got7fsn_ti	myofiber turnover													biological_process											owl:Class	
GO:0060886	biolink:NamedThing	clearance of cells from fusion plate by epithelial to mesenchymal transition	The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.	got7fsn_ti							dph	2009-08-13T12:34:19Z						biological_process											owl:Class	
GO:0044491	biolink:NamedThing	positive regulation of molecular function in other organism	Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism.	got7fsn_ti							jl	2012-02-01T12:21:51Z						biological_process											owl:Class	
GO:0050205	biolink:NamedThing	oxamate carbamoyltransferase activity	Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate.	got7fsn_ti	oxamic transcarbamylase activity|carbamoyl-phosphate:oxamate carbamoyltransferase activity											KEGG_REACTION:R02937|RHEA:22984|MetaCyc:OXAMATE-CARBAMOYLTRANSFERASE-RXN|EC:2.1.3.5		molecular_function											owl:Class	
GO:0090666	biolink:NamedThing	scaRNA localization to Cajal body	A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.	got7fsn_ti							tb	2015-12-15T10:57:05Z						biological_process											owl:Class	
GO:0090670	biolink:NamedThing	RNA localization to Cajal body	A process in which an RNA is transported to, or maintained in, a Cajal body.	got7fsn_ti							tb	2015-12-17T14:04:40Z						biological_process											owl:Class	
GO:0043670	biolink:NamedThing	foot layer	The inner layer of the ectexine.	got7fsn_ti	nexine 1													cellular_component											owl:Class	
GO:0008291	biolink:NamedThing	acetylcholine metabolic process	The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	got7fsn_ti	acetylcholine metabolism													biological_process											owl:Class	
GO:0042133	biolink:NamedThing	neurotransmitter metabolic process	The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.	got7fsn_ti	neurotransmitter metabolism													biological_process											owl:Class	
GO:0060048	biolink:NamedThing	cardiac muscle contraction	Muscle contraction of cardiac muscle tissue.	got7fsn_ti	heart muscle contraction													biological_process											owl:Class	
GO:0000393	biolink:NamedThing	spliceosomal conformational changes to generate catalytic conformation	Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.	got7fsn_ti	3'-splice site cleavage, exon ligation													biological_process											owl:Class	
GO:0004948	biolink:NamedThing	calcitonin receptor activity	Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0071113	biolink:NamedThing	alphaIIb-beta3 integrin-ICAM-4 complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.	got7fsn_ti	ITGAIIb-ITGB3-ICAM4 complex						mah	2009-11-13T02:17:59Z						cellular_component											owl:Class	
GO:0048651	biolink:NamedThing	polyphenic determination, influence by environmental factors	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues.	got7fsn_ti														biological_process											owl:Class	
GO:1990781	biolink:NamedThing	response to immobilization stress combined with electrical stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile.	got7fsn_ti							sl	2015-06-23T20:30:42Z						biological_process											owl:Class	
GO:0051602	biolink:NamedThing	response to electrical stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.	got7fsn_ti	response to electricity													biological_process											owl:Class	
GO:0050453	biolink:NamedThing	cob(II)alamin reductase activity	Catalysis of the reaction: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH.	got7fsn_ti	NADH:cob(II)alamin oxidoreductase activity|vitamin B12 reduction|vitamin B12 reductase activity|NADH2:cob(II)alamin oxidoreductase activity|vitamin B(12r) reductase activity|cob(I)alamin:NAD+ oxidoreductase activity|vitamin B12r reductase activity|B(12r) reductase activity|B12r reductase activity											MetaCyc:COBIIALAMIN-REDUCTASE-RXN|KEGG_REACTION:R00099|EC:1.16.1.4|Reactome:R-HSA-3149560|RHEA:17481		molecular_function											owl:Class	
GO:0140693	biolink:NamedThing	molecular condensate scaffold activity	Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21937					pg	2021-08-09T15:13:52Z						molecular_function											owl:Class	
GO:0044814	biolink:NamedThing	glycolytic fermentation via PFL pathway	The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli.	got7fsn_ti							jl	2013-09-18T16:56:02Z						biological_process											owl:Class	
GO:0070047	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-4 complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).	got7fsn_ti	Stx4-Snap25-Vamp2 complex|SNARE complex (Stx4, Snap25, Vamp2)													cellular_component											owl:Class	
GO:0032111	biolink:NamedThing	activation of protein histidine kinase activity	Any process that initiates the activity of an inactive protein histidine kinase.	got7fsn_ti	protein histidine kinase activator													biological_process											owl:Class	
GO:0010864	biolink:NamedThing	positive regulation of protein histidine kinase activity	Any process that increases the frequency, rate or extent of protein histidine kinase activity.	got7fsn_ti														biological_process											owl:Class	
GO:0030919	biolink:NamedThing	peptidyl-serine O-acetylation	The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine.	got7fsn_ti												RESID:AA0364		biological_process											owl:Class	
GO:0140683	biolink:NamedThing	histone H3-di/monomethyl-lysine-9 demethylase activity	Catalysis of the removal of a methyl group from a di or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone H3K9me demethylase activity|histone H3K9me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089					pg	2021-07-09T06:03:06Z				RHEA:60188|EC:1.14.11.65		molecular_function											owl:Class	
GO:0033505	biolink:NamedThing	floor plate morphogenesis	The process in which the anatomical structure of the floor plate is generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0097566	biolink:NamedThing	left tetrad	Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally).	got7fsn_ti					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:30:43Z						cellular_component											owl:Class	
GO:0106172	biolink:NamedThing	COPI-coated vesicle lumen	The volume enclosed by the membrane of a COPI-coated endocytic vesicle.	got7fsn_ti							hjd	2019-02-11T18:04:08Z						cellular_component											owl:Class	
GO:0052859	biolink:NamedThing	glucan endo-1,4-beta-glucosidase activity	Catalysis of the random hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans.	got7fsn_ti	endo-(1->4)-beta-D-glucanase activity|endo-1,4-beta-glucanase activity|beta-1,4-glucan 4-glucanohydrolase activity|beta-1->4-glucan hydrolase activity|1,4-beta-D-glucan glucanohydrolase activity|beta-1,4-glucan hydrolase activity|endo-1,4-beta-D-glucanase activity|endo-beta-1,4-glucanase activity|beta-1,4-glucanase activity|endo-(1,4)-beta-D-glucanase activity						ai	2011-12-06T03:48:44Z				EC:3.2.1.-		molecular_function											owl:Class	
GO:0018731	biolink:NamedThing	1-oxa-2-oxocycloheptane lactonase activity	Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate.	got7fsn_ti												UM-BBD_reactionID:r0167		molecular_function											owl:Class	
GO:0018461	biolink:NamedThing	fluoren-9-ol dehydrogenase activity	Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+.	got7fsn_ti	9-fluorenol dehydrogenase activity|fluoren-9-ol:NAD(P)+ oxidoreductase activity											UM-BBD_reactionID:r0408|EC:1.1.1.256|MetaCyc:9-FLUORENOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0048907	biolink:NamedThing	anterior lateral line ganglion development	The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.	got7fsn_ti	gALL development													biological_process											owl:Class	
GO:0106153	biolink:NamedThing	phosphorylated histone binding	Binding to a histone in which a residue has been modified by phosphorylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.	got7fsn_ti							hjd	2018-09-19T17:23:06Z						molecular_function											owl:Class	
GO:0140031	biolink:NamedThing	phosphorylation-dependent protein binding	Binding to a protein upon phosphorylation of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require phosphorylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of phosphorylation. It may be that the phosphorylation causes a conformational change that allows binding of the protein to another region; this type of phosphorylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T15:15:19Z						molecular_function											owl:Class	
GO:0009248	biolink:NamedThing	K antigen biosynthetic process	The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.	got7fsn_ti	K antigen biosynthesis|K antigen formation|K antigen synthesis|K antigen anabolism													biological_process											owl:Class	
GO:0046375	biolink:NamedThing	K antigen metabolic process	The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.	got7fsn_ti	K antigen metabolism													biological_process											owl:Class	
GO:0031838	biolink:NamedThing	haptoglobin-hemoglobin complex	A protein complex formed by the stable binding of a haptoglobin to hemoglobin.	got7fsn_ti														cellular_component											owl:Class	
GO:0071839	biolink:NamedThing	apoptotic process in bone marrow cell	The apoptotic process in cells in the bone marrow.	got7fsn_ti	programmed cell death, bone marrow cells|bone marrow cell programmed cell death by apoptosis|killing of bone marrow cells|programmed cell death of bone marrow cells by apoptosis|apoptotic process in bone marrow cell|bone marrow cell apoptosis|apoptosis in bone marrow						mah	2010-09-10T12:19:18Z						biological_process											owl:Class	
GO:0052111	biolink:NamedThing	modification by symbiont of host structure	The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0016586	biolink:NamedThing	RSC-type complex	A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining.	got7fsn_ti	Polybromo- and BAF containing complex|PBAF complex|SWI/SNF complex B	https://github.com/geneontology/go-ontology/issues/14106					mah	2009-04-29T01:07:26Z			GO:0070604			cellular_component											owl:Class	
GO:0034423	biolink:NamedThing	autophagosome lumen	The volume enclosed within the autophagosome double-membrane.	got7fsn_ti	autophagic vacuole lumen				Note that this term should be used for annotating gene products with caution: it should be used only to annotate gene products demonstrated to reside and function normally in the autophagic vacuole lumen, not for molecules that are temporarily found in the lumen prior to degradation.									cellular_component											owl:Class	
GO:0090141	biolink:NamedThing	positive regulation of mitochondrial fission	Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.	got7fsn_ti	positive regulation of mitochondrial division						tb	2009-12-08T02:20:48Z						biological_process											owl:Class	
GO:0006940	biolink:NamedThing	regulation of smooth muscle contraction	Any process that modulates the frequency, rate or extent of smooth muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0046919	biolink:NamedThing	pyruvyltransferase activity	Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another.	got7fsn_ti														molecular_function											owl:Class	
GO:0070746	biolink:NamedThing	interleukin-35 binding	Binding to interleukin-35.	got7fsn_ti	IL-35 binding						mah	2009-06-23T01:15:36Z						molecular_function											owl:Class	
GO:1903012	biolink:NamedThing	positive regulation of bone development	Any process that activates or increases the frequency, rate or extent of bone development.	got7fsn_ti	activation of bone development|up regulation of bone development|up-regulation of bone development|upregulation of bone development						mr	2014-05-13T22:42:06Z						biological_process											owl:Class	
GO:1901137	biolink:NamedThing	carbohydrate derivative biosynthetic process	The chemical reactions and pathways resulting in the formation of carbohydrate derivative.	got7fsn_ti	carbohydrate derivative anabolism|carbohydrate derivative formation|carbohydrate derivative biosynthesis|carbohydrate derivative synthesis						bf	2012-07-12T04:05:39Z						biological_process											owl:Class	
GO:0030840	biolink:NamedThing	negative regulation of intermediate filament polymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization.	got7fsn_ti	down-regulation of intermediate filament polymerization|down regulation of intermediate filament polymerization|inhibition of intermediate filament polymerization|negative regulation of intermediate filament polymerization and/or depolymerization|downregulation of intermediate filament polymerization				Note that this term was split from 'negative regulation of intermediate filament polymerization and/or depolymerization ; GO:0045825' (sibling term 'negative regulation of intermediate filament depolymerization ; GO:0030843').									biological_process											owl:Class	
GO:0046204	biolink:NamedThing	nor-spermidine metabolic process	The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	got7fsn_ti	nor-spermidine metabolism													biological_process											owl:Class	
GO:0034814	biolink:NamedThing	7,8-dihydroxy benzo(a)pyrene dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r1138		molecular_function											owl:Class	
GO:0072071	biolink:NamedThing	kidney interstitial fibroblast differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.	got7fsn_ti	kidney interstitial cell differentiation						mah	2010-01-25T04:34:31Z						biological_process											owl:Class	
GO:0060010	biolink:NamedThing	Sertoli cell fate commitment	The process in which the cellular identity of Sertoli cells is acquired and determined.	got7fsn_ti														biological_process											owl:Class	
GO:0036013	biolink:NamedThing	cyanelle outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope.	got7fsn_ti							bf	2011-10-10T01:50:56Z						cellular_component											owl:Class	
GO:0045466	biolink:NamedThing	R7 cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor.	got7fsn_ti														biological_process											owl:Class	
GO:0001751	biolink:NamedThing	compound eye photoreceptor cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.	got7fsn_ti														biological_process											owl:Class	
GO:0033062	biolink:NamedThing	Rhp55-Rhp57 complex	A conserved heterodimeric DNA recombinase mediator complex that contains the RecA family proteins Rhp55p and Rph57 in Schizosaccharomyces, or orthologs thereof (e.g. Rad55p and Rad57p in Saccharomyces).	got7fsn_ti	Rad55-Rad57 complex													cellular_component											owl:Class	
GO:0016444	biolink:NamedThing	somatic cell DNA recombination	Recombination occurring within or between DNA molecules in somatic cells.	got7fsn_ti														biological_process											owl:Class	
GO:0046292	biolink:NamedThing	formaldehyde metabolic process	The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.	got7fsn_ti	formaldehyde metabolism|methanal metabolism|methanal metabolic process													biological_process											owl:Class	
GO:0008795	biolink:NamedThing	NAD+ synthase activity	Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+.	got7fsn_ti	NAD synthase activity|diphosphopyridine nucleotide synthetase activity|NAD(+) synthetase activity|nicotinamide adenine dinucleotide synthetase activity|NAD synthetase activity|NAD synthase (AMP-forming)|deamido-NAD+:ammonia ligase (AMP-forming)|NAD+ synthetase activity										GO:0016965|GO:0008749	EC:6.3.1.5|MetaCyc:NAD-SYNTH-NH3-RXN|RHEA:21188		molecular_function											owl:Class	
GO:1990151	biolink:NamedThing	protein localization to cell tip	A process in which a protein is transported to, or maintained in, a location at the cell tip.	got7fsn_ti	protein localisation to cell tip						mah	2013-07-31T14:56:40Z						biological_process											owl:Class	
GO:0060571	biolink:NamedThing	morphogenesis of an epithelial fold	The morphogenetic process in which an epithelial sheet bends along a linear axis.	got7fsn_ti	epithelial folding|folding of an epithelial sheet						dph	2009-04-30T09:27:17Z						biological_process											owl:Class	
GO:0051458	biolink:NamedThing	corticotropin secretion	The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.	got7fsn_ti	adrenotropin secretion|adrenocorticotropin secretion|adrenocorticotropic hormone secretion|ACTH secretion|corticotropic hormone secretion|adrenotropic hormone secretion													biological_process											owl:Class	
GO:0005656	biolink:NamedThing	nuclear pre-replicative complex	A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.	got7fsn_ti	pre-replicative complex|pre-RC|eukaryotic pre-replicative complex													cellular_component											owl:Class	
GO:0036387	biolink:NamedThing	pre-replicative complex	A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.	got7fsn_ti	pre-replication complex|pre-RC				This term describes pre-replicative complexes across organisms.		bf	2013-06-05T16:14:52Z						cellular_component											owl:Class	
GO:0004658	biolink:NamedThing	propionyl-CoA carboxylase activity	Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA.	got7fsn_ti	propanoyl-CoA:carbon-dioxide ligase (ADP-forming)|propionyl coenzyme A carboxylase activity|PCCase activity											Reactome:R-HSA-71031|EC:6.4.1.3|MetaCyc:PROPIONYL-COA-CARBOXY-RXN|RHEA:23720		molecular_function											owl:Class	
GO:0016421	biolink:NamedThing	CoA carboxylase activity	Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0018305	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulphide											RESID:AA0288		biological_process											owl:Class	
GO:0006097	biolink:NamedThing	glyoxylate cycle	A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.	got7fsn_ti	glyoxylate bypass											MetaCyc:GLYOXYLATE-BYPASS|Wikipedia:Glyoxylate_cycle		biological_process											owl:Class	
GO:0061678	biolink:NamedThing	Entner-Doudoroff pathway	A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate.	got7fsn_ti							dph	2015-01-16T15:28:25Z				MetaCyc:Entner-Doudoroff-Pathways		biological_process											owl:Class	
GO:1990404	biolink:NamedThing	protein ADP-ribosylase activity	The transfer, from NAD, of ADP-ribose to a protein amino acid residue.	got7fsn_ti	ribosylase activity						pg	2014-06-24T07:04:44Z						molecular_function											owl:Class	
GO:0018760	biolink:NamedThing	thiocyanate hydrolase activity	Catalysis of the reaction: H(2)O + 2 H(+) + thiocyanate = carbonyl sulfide + NH(4)(+).	got7fsn_ti	thiocyanate aminohydrolase activity											EC:3.5.5.8|RHEA:21464|MetaCyc:RXN-1761|KEGG_REACTION:R05780|UM-BBD_reactionID:r0598		molecular_function											owl:Class	
GO:0016815	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.	got7fsn_ti												EC:3.5.5.-		molecular_function											owl:Class	
GO:0060431	biolink:NamedThing	primary lung bud formation	The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.	got7fsn_ti	lung formation													biological_process											owl:Class	
GO:0060572	biolink:NamedThing	morphogenesis of an epithelial bud	The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.	got7fsn_ti							dph	2009-04-30T09:38:35Z						biological_process											owl:Class	
GO:0003146	biolink:NamedThing	heart jogging	The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.	got7fsn_ti	cardiac jogging						tb	2009-09-22T06:11:41Z						biological_process											owl:Class	
GO:0046252	biolink:NamedThing	toluene biosynthetic process	The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.	got7fsn_ti	toluene synthesis|toluene formation|toluene biosynthesis|toluene anabolism				This term was reinstated from obsolete.									biological_process											owl:Class	
GO:0002151	biolink:NamedThing	G-quadruplex RNA binding	Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.	got7fsn_ti	G quartet RNA binding|G quartet binding|G-quartet binding|G quadruplex binding				The structures of RNA and DNA G quartets differ regarding sugar conformation so that a protein binding to the RNA structure might not bind to the DNA structure.		hjd	2009-10-22T01:38:02Z						molecular_function											owl:Class	
GO:0006033	biolink:NamedThing	chitin localization	A process in which chitin is transported to, or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of chitin localization|chitin localisation													biological_process											owl:Class	
GO:0001094	biolink:NamedThing	TFIID-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	got7fsn_ti	TFIID-class transcription factor binding						krc	2010-10-28T02:48:33Z						molecular_function											owl:Class	
GO:0045507	biolink:NamedThing	interleukin-25 receptor activity	Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-25 receptor activity|IL-25R													molecular_function											owl:Class	
GO:0102278	biolink:NamedThing	N,N'-diacetylchitobiose synthase activity	Catalysis of the reaction: n H2O + chitin <=> N,N'-diacetylchitobiose.	got7fsn_ti												MetaCyc:RXN-12554		molecular_function											owl:Class	
GO:0070064	biolink:NamedThing	proline-rich region binding	Binding to a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0055120	biolink:NamedThing	striated muscle dense body	A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.	got7fsn_ti														cellular_component											owl:Class	
GO:0001673	biolink:NamedThing	male germ cell nucleus	The nucleus of a male germ cell, a reproductive cell in males.	got7fsn_ti	male germ-cell nucleus										GO:0043081			cellular_component											owl:Class	
GO:0043073	biolink:NamedThing	germ cell nucleus	The nucleus of a germ cell, a reproductive cell in multicellular organisms.	got7fsn_ti	germ-cell nucleus													cellular_component											owl:Class	
GO:0042092	biolink:NamedThing	type 2 immune response	An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.	got7fsn_ti	T-helper 2 type immune response|Th2 immune response													biological_process											owl:Class	
GO:0033779	biolink:NamedThing	5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity	Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+).	got7fsn_ti	5beta-cholestane-3alpha,7alpha-diol 12alpha-monooxygenase activity|5beta-cholestane-3alpha,7alpha-diol,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity|CYP8B1|sterol 12alpha-hydroxylase activity|cytochrome P450 8B1											MetaCyc:1.14.13.96-RXN|RHEA:15261|KEGG_REACTION:R07204|EC:1.14.14.139		molecular_function											owl:Class	
GO:0000330	biolink:NamedThing	plant-type vacuole lumen	The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana.	got7fsn_ti	lumen of vacuole with cell cycle-independent morphology													cellular_component											owl:Class	
GO:0090549	biolink:NamedThing	response to carbon starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source.	got7fsn_ti							tb	2013-04-22T13:57:16Z						biological_process											owl:Class	
GO:0070256	biolink:NamedThing	negative regulation of mucus secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.	got7fsn_ti	negative regulation of mucus production													biological_process											owl:Class	
GO:0045822	biolink:NamedThing	negative regulation of heart contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.	got7fsn_ti	inhibition of heart contraction|down-regulation of heart contraction|downregulation of heart contraction|down regulation of heart contraction|negative regulation of cardiac contraction													biological_process											owl:Class	
GO:0061281	biolink:NamedThing	specification of mesonephric connecting tubule identity	The process in which the connecting tubule of the mesonephric nephron acquires its identity.	got7fsn_ti	specification of mesonephric collecting tubule identity						dph	2010-09-02T01:26:09Z						biological_process											owl:Class	
GO:0072085	biolink:NamedThing	specification of connecting tubule identity	The process in which the connecting tubule of the kidney nephron acquires its identity.	got7fsn_ti							mah	2010-02-01T02:49:11Z						biological_process											owl:Class	
GO:0080185	biolink:NamedThing	effector-mediated induction of plant hypersensitive response by symbiont	A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes).	got7fsn_ti	induction by organism of pathogen-race/host plant cultivar-specific resistance in host|positive regulation by organism of defense response in host by specific elicitors|positive regulation by symbiont of host resistance gene-dependent defense response|induction by organism of defense response in host by specific elicitors|induction by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction|avirulence protein|activation of hypersensitive response|activation by organism of defense response in host by specific elicitors|positive regulation by symbiont of plant hypersensitive response|ETI-triggered of host innate immune response|activation by organism of host resistance gene-dependent defense response|activation by symbiont of host resistance gene-dependent defense response|induction by symbiont of host resistance gene-dependent defense response|effector-triggered immunity|positive regulation by organism of host gene-for-gene resistance|necrotrophic effector|positive regulation by symbiont of plant HR|effector-triggered necrosis|induction by organism of host gene-for-gene resistance|activation by organism of host gene-for-gene resistance|activation of HR|effector-triggered induction of host innate immune response|effector-triggered induction of plant hypersensitive response by symbiont|induction of effector-triggered immunity (ETI)|ETI triggered of host innate immune response	https://github.com/geneontology/go-ontology/issues/18694					dhl	2011-08-10T04:33:53Z			GO:0052101|GO:0052286|GO:0052527|GO:0052423	Wikipedia:Effector-triggered_immunity		biological_process											owl:Class	
GO:0052158	biolink:NamedThing	modulation by symbiont of host resistance gene-dependent defense response	Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of host gene-for-gene resistance|modulation by organism of pathogen-race/host plant cultivar-specific resistance in symbiont|modulation by organism of defense response in host by specific elicitors|modulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction										GO:0052297			biological_process											owl:Class	
GO:0002873	biolink:NamedThing	positive regulation of natural killer cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.	got7fsn_ti	up regulation of natural killer cell tolerance induction|activation of natural killer cell tolerance induction|positive regulation of NK cell tolerance induction|up-regulation of natural killer cell tolerance induction|upregulation of natural killer cell tolerance induction|stimulation of natural killer cell tolerance induction													biological_process											owl:Class	
GO:0002673	biolink:NamedThing	regulation of acute inflammatory response	Any process that modulates the frequency, rate, or extent of an acute inflammatory response.	got7fsn_ti														biological_process											owl:Class	
GO:0050311	biolink:NamedThing	sulfite reductase (ferredoxin) activity	Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin.	got7fsn_ti	ferredoxin-sulfite reductase activity|sulphite reductase (ferredoxin) activity|hydrogen-sulfide:ferredoxin oxidoreductase activity											MetaCyc:SULFITE-REDUCTASE-FERREDOXIN-RXN|EC:1.8.7.1|RHEA:23132		molecular_function											owl:Class	
GO:0016673	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	got7fsn_ti	oxidoreductase activity, acting on sulphur group of donors, iron-sulphur protein as acceptor											EC:1.8.7.-		molecular_function											owl:Class	
GO:0052920	biolink:NamedThing	(2R)-2-hydroxy-2-methylbutanenitrile lyase activity	Catalysis of the reaction: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide.	got7fsn_ti												MetaCyc:RXN-11733|RHEA:28170|KEGG_REACTION:R09358|EC:4.1.2.46		molecular_function											owl:Class	
GO:0097727	biolink:NamedThing	blepharoplast	An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell.	got7fsn_ti					The blepharoplast should not be confused with a basal body; rather, it acts as the precursor assembly zone for multiple basal bodies.		pr	2016-09-23T10:57:18Z						cellular_component											owl:Class	
GO:0019654	biolink:NamedThing	acetate fermentation	The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.	got7fsn_ti												MetaCyc:P142-PWY		biological_process											owl:Class	
GO:0006083	biolink:NamedThing	acetate metabolic process	The chemical reactions and pathways involving acetate, the anion of acetic acid.	got7fsn_ti	acetate metabolism													biological_process											owl:Class	
GO:0033571	biolink:NamedThing	lactoferrin transport	The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0006826	biolink:NamedThing	iron ion transport	The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	ferric iron transport|ferric ion import|iron transport|iron ion import|ferric ion transport|ferric iron uptake|ferrous iron transport|ferrous ion transport|ferric iron import						pr	2012-04-18T03:33:45Z			GO:0097286|GO:0015682|GO:0015681|GO:0033216|GO:0015684			biological_process											owl:Class	
GO:0052740	biolink:NamedThing	1-acyl-2-lysophosphatidylserine acylhydrolase activity	Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate.	got7fsn_ti	phosphatidylserine-specific phospholipase A1 activity											EC:3.1.1.32		molecular_function											owl:Class	
GO:0061812	biolink:NamedThing	cyclic ADP-ribose hydrolase	Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR).	got7fsn_ti							dph	2016-11-11T13:32:43Z						molecular_function											owl:Class	
GO:0009664	biolink:NamedThing	plant-type cell wall organization	A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	plant-type cell wall organization and biogenesis|plant-type cell wall organisation|cellulose and pectin-containing cell wall organization and biogenesis|cell wall organization and biogenesis													biological_process											owl:Class	
GO:0016754	biolink:NamedThing	sinapoylglucose-malate O-sinapoyltransferase activity	Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate.	got7fsn_ti	1-sinapoylglucose-L-malate sinapoyltransferase activity|1-O-sinapoyl-beta-D-glucose:(S)-malate O-sinapoyltransferase activity|sinapoylglucose:malate sinapoyltransferase activity											MetaCyc:2.3.1.92-RXN|EC:2.3.1.92|RHEA:12625|KEGG_REACTION:R03323		molecular_function											owl:Class	
GO:0016753	biolink:NamedThing	O-sinapoyltransferase activity	Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:1990102	biolink:NamedThing	DnaA-DiaA complex	A protein-DNA complex containing a tetramer of DiaA attached to multiple  DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA.	got7fsn_ti	DnaA-DiaA-DNA complex						bhm	2013-05-14T12:33:59Z						cellular_component											owl:Class	
GO:1990077	biolink:NamedThing	primosome complex	Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms.  Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.	got7fsn_ti	primosome						bhm	2013-04-26T11:55:28Z						cellular_component											owl:Class	
GO:1900540	biolink:NamedThing	fumonisin catabolic process	The chemical reactions and pathways resulting in the breakdown of fumonisin.	got7fsn_ti	fumonisin degradation|fumonisin catabolism|fumonisin breakdown						tb	2012-05-11T12:54:12Z						biological_process											owl:Class	
GO:0035985	biolink:NamedThing	senescence-associated heterochromatin focus	A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.	got7fsn_ti	senescence-associated heterochromatin foci|SAHF						bf	2011-08-25T04:36:40Z						cellular_component											owl:Class	
GO:0034230	biolink:NamedThing	enkephalin processing	The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.	got7fsn_ti	enkephalin formation|peptide enkephalin formation|peptide enkephalin processing													biological_process											owl:Class	
GO:0018276	biolink:NamedThing	isopeptide cross-linking via N6-glycyl-L-lysine	The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination.	got7fsn_ti					See also the biological process term 'peptide cross-linking via S-glycyl-L-cysteine ; GO:0018255'.							RESID:AA0125		biological_process											owl:Class	
GO:0042794	biolink:NamedThing	plastid rRNA transcription	The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase.	got7fsn_ti	rRNA transcription from plastid promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0042793	biolink:NamedThing	plastid transcription	The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase.	got7fsn_ti	transcription from plastid promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0140643	biolink:NamedThing	hydroxymethylglutaryl-CoA reductase (NADH) activity	Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) <=> 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.	got7fsn_ti	beta-hydroxy-beta-methylglutaryl CoA-reductase activity|3-hydroxy-3-methylglutaryl coenzyme A reductase activity|beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity|hydroxymethylglutaryl coenzyme A reductase activity|HMG-CoA reductase activity	https://github.com/geneontology/go-ontology/issues/21411			Note that this activity is not present in eukaryotes, see PMID:29224355.		pg	2021-05-11T16:00:35Z				KEGG_REACTION:R02081|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN|EC:1.1.1.88|RHEA:14833		molecular_function											owl:Class	
GO:0061180	biolink:NamedThing	mammary gland epithelium development	The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	got7fsn_ti	breast epithelium development						dph	2010-07-14T08:18:24Z						biological_process											owl:Class	
GO:0060429	biolink:NamedThing	epithelium development	The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	got7fsn_ti														biological_process											owl:Class	
GO:0097370	biolink:NamedThing	protein O-GlcNAcylation via threonine	The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine.	got7fsn_ti							pr	2012-08-06T16:57:37Z						biological_process											owl:Class	
GO:0097669	biolink:NamedThing	SCF-Skp2 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae.	got7fsn_ti							pr	2014-10-06T10:28:52Z						cellular_component											owl:Class	
GO:0050316	biolink:NamedThing	T2-induced deoxynucleotide kinase activity	Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP.	got7fsn_ti	ATP:(d)NMP phosphotransferase activity											EC:2.7.4.12|MetaCyc:GMKALT-RXN|RHEA:12697		molecular_function											owl:Class	
GO:0071479	biolink:NamedThing	cellular response to ionizing radiation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.	got7fsn_ti	cellular response to ionizing radiation stimulus|cellular response to ionising radiation						mah	2009-12-18T02:00:31Z						biological_process											owl:Class	
GO:0004162	biolink:NamedThing	dimethylnitrosamine demethylase activity	Catalysis of the removal of a methyl group from N-nitrosodimethylamine.	got7fsn_ti	N-nitrosodimethylamine demethylase activity													molecular_function											owl:Class	
GO:0032507	biolink:NamedThing	maintenance of protein location in cell	Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.	got7fsn_ti	maintenance of protein localization in cell													biological_process											owl:Class	
GO:0044364	biolink:NamedThing	disruption of cells of other organism	A process in which an organism has a negative effect on the functioning of the second organism's cells.	got7fsn_ti							jl	2011-10-27T02:27:48Z						biological_process											owl:Class	
GO:0021844	biolink:NamedThing	interneuron sorting involved in substrate-independent cerebral cortex tangential migration	The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures.	got7fsn_ti														biological_process											owl:Class	
GO:0034715	biolink:NamedThing	pICln-Sm protein complex	A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG.	got7fsn_ti	6S pICln complex													cellular_component											owl:Class	
GO:0021960	biolink:NamedThing	anterior commissure morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.	got7fsn_ti														biological_process											owl:Class	
GO:0002335	biolink:NamedThing	mature B cell differentiation	The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.	got7fsn_ti	mature B lymphocyte differentiation|mature cell development|mature B-cell differentiation|mature B-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0006424	biolink:NamedThing	glutamyl-tRNA aminoacylation	The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0007183	biolink:NamedThing	SMAD protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.	got7fsn_ti	SMAD protein heteromerization													biological_process											owl:Class	
GO:1990179	biolink:NamedThing	protein localization to actomyosin contractile ring	A process in which a protein is transported to, or maintained at, the actomyosin contractile ring.	got7fsn_ti	protein localisation to actomyosin contractile ring						mah	2013-08-30T16:13:54Z						biological_process											owl:Class	
GO:0071880	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	got7fsn_ti	adrenergic receptor, adenylate cyclase activating pathway|activation of adenylate cyclase activity by adrenergic receptor signalling pathway|adrenergic receptor, adenylyl cyclase activating pathway|activation of adenylate cyclase activity by adrenergic receptor signaling pathway						mah	2010-09-13T04:21:28Z						biological_process											owl:Class	
GO:0071875	biolink:NamedThing	adrenergic receptor signaling pathway	A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.	got7fsn_ti	adrenoceptor signaling pathway|adrenergic receptor signalling pathway						mah	2010-09-13T03:44:44Z						biological_process											owl:Class	
GO:0047132	biolink:NamedThing	dihydrobenzophenanthridine oxidase activity	Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine.	got7fsn_ti	dihydrobenzophenanthridine:oxygen oxidoreductase activity											EC:1.5.3.12|MetaCyc:1.5.3.12-RXN|RHEA:16621		molecular_function											owl:Class	
GO:0071860	biolink:NamedThing	proctolin receptor binding	Binding to a proctolin receptor.	got7fsn_ti							mah	2010-09-10T03:24:19Z						molecular_function											owl:Class	
GO:0097146	biolink:NamedThing	NOXA-BCL-xl complex	A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:49:00Z						cellular_component											owl:Class	
GO:0019115	biolink:NamedThing	benzaldehyde dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.	got7fsn_ti												EC:1.2.1.-		molecular_function											owl:Class	
GO:0004030	biolink:NamedThing	aldehyde dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.	got7fsn_ti	ALDH|aldehyde:NAD(P)+ oxidoreductase activity											MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN|Reactome:R-HSA-5692283|Reactome:R-HSA-5696080|Reactome:R-HSA-6808464|EC:1.2.1.5		molecular_function											owl:Class	
GO:0006999	biolink:NamedThing	nuclear pore organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore.	got7fsn_ti	nuclear pore complex organization and biogenesis|nuclear pore organization and biogenesis|nuclear pore organisation													biological_process											owl:Class	
GO:0046584	biolink:NamedThing	enniatin metabolic process	The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.	got7fsn_ti	enniatin metabolism													biological_process											owl:Class	
GO:0061070	biolink:NamedThing	female urethra development	The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.	got7fsn_ti							dph	2010-03-12T08:29:43Z						biological_process											owl:Class	
GO:0061068	biolink:NamedThing	urethra development	The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.	got7fsn_ti							dph	2010-03-12T08:24:52Z						biological_process											owl:Class	
GO:0000994	biolink:NamedThing	RNA polymerase III core binding	Binding to an RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.	got7fsn_ti							krc	2010-08-11T03:58:58Z						molecular_function											owl:Class	
GO:0030744	biolink:NamedThing	luteolin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	o-diphenol m-O-methyltransferase activity|S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase activity|S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase activity|luteolin methyltransferase activity|o-dihydric phenol methyltransferase activity|o-dihydric phenol meta-O-methyltransferase activity|luteolin 3'-O-methyltransferase activity											RHEA:14589|MetaCyc:LUTEOLIN-O-METHYLTRANSFERASE-RXN|EC:2.1.1.42|KEGG_REACTION:R03587		molecular_function											owl:Class	
GO:0004787	biolink:NamedThing	thiamine-diphosphatase activity	Catalysis of the reaction: TPP + H2O = TMP + phosphate.	got7fsn_ti	TPPase activity|thiamin-pyrophosphatase activity|thiaminpyrophosphatase activity|thiamine pyrophosphatase activity|thiamin pyrophosphatase activity											RHEA:27998		molecular_function											owl:Class	
GO:0050451	biolink:NamedThing	CoA-disulfide reductase activity	Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+.	got7fsn_ti	CoA-disulfide reductase (NAD(P)H) activity|coenzyme A disulfide reductase activity|CoA:NAD(P)+ oxidoreductase activity|NADH:CoA-disulfide oxidoreductase activity|CoA-disulfide reductase (NADH2)|CoA-disulfide reductase (NADH) activity|CoA:NAD+ oxidoreductase activity|CoADR activity|NADH2:CoA-disulfide oxidoreductase activity|CoA-disulfide reductase [NAD(P)H]|CoA-disulphide reductase activity											EC:1.8.1.14|MetaCyc:COA-DISULFIDE-REDUCTASE-NADH-RXN|RHEA:14705		molecular_function											owl:Class	
GO:0052590	biolink:NamedThing	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol.	got7fsn_ti					Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591.							MetaCyc:RXN0-5258|EC:1.1.5.3		molecular_function											owl:Class	
GO:0004368	biolink:NamedThing	glycerol-3-phosphate dehydrogenase (quinone) activity	Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.	got7fsn_ti	sn-glycerol-3-phosphate dehydrogenase activity|sn-glycerol-3-phosphate:quinone oxidoreductase activity|flavin-linked glycerol-3-phosphate dehydrogenase|glycerol-3-phosphate CoQ reductase|FAD-dependent glycerol-3-phosphate dehydrogenase|glycerophosphate dehydrogenase activity|L-glycerophosphate dehydrogenase activity				Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591.							MetaCyc:RXN0-5260|Reactome:R-HSA-188467|MetaCyc:RXN-9927|RHEA:18977|EC:1.1.5.3		molecular_function											owl:Class	
GO:0032174	biolink:NamedThing	cellular bud neck septin collar	A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck.	got7fsn_ti														cellular_component											owl:Class	
GO:0007622	biolink:NamedThing	rhythmic behavior	The specific behavior of an organism that recur with measured regularity.	got7fsn_ti	rhythmic behaviour|rhythmic behavioral response to stimulus|rhythmic behavioural response to stimulus													biological_process											owl:Class	
GO:0044545	biolink:NamedThing	NSL complex	A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1.	got7fsn_ti	non-specific lethal complex						jl	2012-03-22T12:49:18Z						cellular_component											owl:Class	
GO:0019665	biolink:NamedThing	anaerobic amino acid catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP.	got7fsn_ti	amino acid fermentation													biological_process											owl:Class	
GO:0001067	biolink:NamedThing	transcription regulatory region nucleic acid binding	Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.	got7fsn_ti	regulatory region nucleic acid binding	https://github.com/geneontology/go-ontology/issues/20791					krc	2010-10-21T04:08:56Z						molecular_function											owl:Class	
GO:0003676	biolink:NamedThing	nucleic acid binding	Binding to a nucleic acid.	got7fsn_ti	base pairing										GO:0000496			molecular_function											owl:Class	
GO:0044059	biolink:NamedThing	modulation by symbiont of host endocrine process	The alteration by a symbiont organism of the functioning of a endocrine process, any of the hormonal, neural, and secretory processes that release products into the blood or lymph, in the host organism.	got7fsn_ti	regulation by symbiont of host endocrine process													biological_process											owl:Class	
GO:0044060	biolink:NamedThing	regulation of endocrine process	Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.	got7fsn_ti	regulation of endocrine system process													biological_process											owl:Class	
GO:0043165	biolink:NamedThing	Gram-negative-bacterium-type cell outer membrane assembly	The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.	got7fsn_ti	cell outer membrane biogenesis													biological_process											owl:Class	
GO:0002746	biolink:NamedThing	antigen processing and presentation following pinocytosis	Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0035516	biolink:NamedThing	oxidative DNA demethylase activity	Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O(2) =  a nucleobase within DNA + formaldehyde + succinate + CO(2).	got7fsn_ti	N1-methyladenine demethylase activity|2-oxoglutarate-dependent DNA demethylase|N3-methylcytosine demethylase activity|1-ethyladenine demethylase activity	https://github.com/geneontology/go-ontology/issues/21159					bf	2010-04-30T02:38:16Z			GO:0103052|GO:0103051|GO:0103053	EC:1.14.11.33|MetaCyc:RXN0-985|MetaCyc:RXN0-984|RHEA:30299|MetaCyc:RXN0-986		molecular_function											owl:Class	
GO:0072714	biolink:NamedThing	response to selenite ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.	got7fsn_ti							mah	2012-04-19T02:46:28Z						biological_process											owl:Class	
GO:0070944	biolink:NamedThing	neutrophil-mediated killing of bacterium	The directed killing of a bacterium by a neutrophil.	got7fsn_ti	neutrophil mediated killing of bacterium						mah	2009-10-01T01:55:56Z						biological_process											owl:Class	
GO:0070943	biolink:NamedThing	neutrophil-mediated killing of symbiont cell	The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	neutrophil mediated killing of symbiont cell						mah	2009-10-01T01:52:03Z						biological_process											owl:Class	
GO:0019237	biolink:NamedThing	centromeric DNA binding	Binding to a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis.	got7fsn_ti	centromere binding													molecular_function											owl:Class	
GO:1990837	biolink:NamedThing	sequence-specific double-stranded DNA binding	Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.	got7fsn_ti	sequence-specific dsDNA binding						sl	2015-08-25T17:30:06Z						molecular_function											owl:Class	
GO:0102667	biolink:NamedThing	indole-3-acetyl-beta-1-D-glucose hydrolase activity	Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-3165		molecular_function											owl:Class	
GO:0016788	biolink:NamedThing	hydrolase activity, acting on ester bonds	Catalysis of the hydrolysis of any ester bond.	got7fsn_ti	esterase activity											Reactome:R-HSA-9023619|Reactome:R-HSA-162729|Reactome:R-HSA-9023617|EC:3.1.-.-		molecular_function											owl:Class	
GO:0048459	biolink:NamedThing	floral whorl structural organization	The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	floral whorl structural organisation										GO:0048416			biological_process											owl:Class	
GO:0070435	biolink:NamedThing	Shc-EGFR complex	A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway.	got7fsn_ti	Shc-Egfr complex, EGF stimulated													cellular_component											owl:Class	
GO:0010701	biolink:NamedThing	positive regulation of norepinephrine secretion	Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.	got7fsn_ti														biological_process											owl:Class	
GO:0070531	biolink:NamedThing	BRCA1-A complex	A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.	got7fsn_ti														cellular_component											owl:Class	
GO:0072330	biolink:NamedThing	monocarboxylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.	got7fsn_ti	monocarboxylic acid synthesis|monocarboxylic acid biosynthesis|monocarboxylic acid anabolism|monocarboxylic acid formation						mah	2010-11-02T04:51:32Z						biological_process											owl:Class	
GO:0032787	biolink:NamedThing	monocarboxylic acid metabolic process	The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).	got7fsn_ti	monocarboxylic acid metabolism|monocarboxylate metabolic process													biological_process											owl:Class	
GO:0047388	biolink:NamedThing	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase	Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)].	got7fsn_ti	adenylyl(glutamine synthetase) hydrolase activity|adenylyl-glutamate-ammonia ligase hydrolase activity|adenylyl-L-glutamate:ammonia ligase (ADP-forming) adenylylhydrolase activity|adenylyl-[glutamate-ammonia ligase] hydrolase activity|adenylyl-glutamine-synthetasehydrolase activity				Formerly EC:3.1.4.15.							RHEA:43716|EC:2.7.7.89|MetaCyc:3.1.4.15-RXN|KEGG_REACTION:R03474		molecular_function											owl:Class	
GO:0008787	biolink:NamedThing	allose kinase activity	Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate.	got7fsn_ti	allokinase activity|D-allokinase activity|ATP:D-allose 6-phosphotransferase activity|D-allose-6-kinase activity|allokinase (phosphorylating)											MetaCyc:ALLOSE-KINASE-RXN|EC:2.7.1.55|RHEA:14805		molecular_function											owl:Class	
GO:0010285	biolink:NamedThing	L,L-diaminopimelate aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+).	got7fsn_ti	LL-diaminopimelate aminotransferase activity|LL-DAP aminotransferase activity|LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity|LL-diaminopimelate transaminase activity|LL-DAP-AT activity										GO:0043742	KEGG_REACTION:R07613|EC:2.6.1.83|RHEA:23988|MetaCyc:RXN-7737		molecular_function											owl:Class	
GO:0072356	biolink:NamedThing	chromosome passenger complex localization to kinetochore	A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.	got7fsn_ti	chromosome passenger complex localisation to kinetochore|CPC localization to kinetochore|chromosomal passenger complex localization to kinetochore|CPC complex localization to kinetochore						mah	2010-11-15T11:30:38Z						biological_process											owl:Class	
GO:0045492	biolink:NamedThing	xylan biosynthetic process	The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.	got7fsn_ti	xylan biosynthesis|xylan anabolism|xylan formation|xylan synthesis													biological_process											owl:Class	
GO:0070592	biolink:NamedThing	cell wall polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.	got7fsn_ti	cell wall polysaccharide synthesis|cell wall polysaccharide anabolism|cell wall polysaccharide biosynthesis						mah	2009-04-28T01:25:54Z						biological_process											owl:Class	
GO:0070611	biolink:NamedThing	histone methyltransferase activity (H3-R2 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3.	got7fsn_ti	histone-arginine N-methyltransferase activity (H3-R2 specific)|histone methylase activity (H3-R2 specific)						mah	2009-04-29T02:04:44Z						molecular_function											owl:Class	
GO:0003181	biolink:NamedThing	atrioventricular valve morphogenesis	The process in which the structure of the atrioventricular valve is generated and organized.	got7fsn_ti	AV valve morphogenesis						dph	2009-10-08T11:31:59Z						biological_process											owl:Class	
GO:0050863	biolink:NamedThing	regulation of T cell activation	Any process that modulates the frequency, rate or extent of T cell activation.	got7fsn_ti	regulation of T lymphocyte activation|regulation of T-lymphocyte activation|regulation of T-cell activation													biological_process											owl:Class	
GO:0071258	biolink:NamedThing	cellular response to gravity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.	got7fsn_ti	cellular response to gravitational stimulus						mah	2009-12-04T03:31:36Z						biological_process											owl:Class	
GO:0060641	biolink:NamedThing	mammary gland duct regression in males	The process in which the epithelium of the mammary duct is destroyed in males.	got7fsn_ti							dph	2009-05-20T04:50:57Z						biological_process											owl:Class	
GO:0071104	biolink:NamedThing	response to interleukin-9	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.	got7fsn_ti	response to IL-9						mah	2009-11-09T12:50:25Z						biological_process											owl:Class	
GO:0048924	biolink:NamedThing	posterior lateral line neuromast mantle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.	got7fsn_ti														biological_process											owl:Class	
GO:0048888	biolink:NamedThing	neuromast mantle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.	got7fsn_ti														biological_process											owl:Class	
GO:0034324	biolink:NamedThing	O-hexanoyltransferase activity	Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0034327	biolink:NamedThing	hexanoyltransferase activity	Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0003247	biolink:NamedThing	post-embryonic cardiac muscle cell growth involved in heart morphogenesis	The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart.	got7fsn_ti							dph	2009-10-13T11:50:29Z						biological_process											owl:Class	
GO:0047475	biolink:NamedThing	phenylacetate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H(+) + phenylacetyl-CoA.	got7fsn_ti	phenylacetyl-CoA ligase (AMP-forming)|phenacyl coenzyme A synthetase activity|phenylacetate:CoA ligase (AMP-forming)|PA-CoA ligase activity|phenylacetyl-CoA ligase activity											KEGG_REACTION:R02539|MetaCyc:PHENYLACETATE--COA-LIGASE-RXN|EC:6.2.1.30|RHEA:20956		molecular_function											owl:Class	
GO:0071620	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues	The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans).	got7fsn_ti							mah	2010-02-09T02:39:52Z						biological_process											owl:Class	
GO:0070816	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain	The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex.	got7fsn_ti	generation of hyperphosphorylated CTD of RNA polymerase II|generation of II(0) form of RNA polymerase II|CTD domain phosphorylation of RNA polymerase II|hyperphosphorylation of RNA polymerase II C-terminal domain						mah	2009-07-13T04:01:19Z			GO:0016245			biological_process											owl:Class	
GO:1905742	biolink:NamedThing	Ras guanyl-nucleotide exchange factor complex	A protein complex which is capable of Ras guanyl-nucleotide exchange factor activity.	got7fsn_ti							rjd	2016-12-06T10:24:29Z						cellular_component											owl:Class	
GO:0002104	biolink:NamedThing	endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0002103	biolink:NamedThing	endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0070260	biolink:NamedThing	5'-tyrosyl-DNA phosphodiesterase activity	Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.	got7fsn_ti					See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'.									molecular_function											owl:Class	
GO:0004660	biolink:NamedThing	protein farnesyltransferase activity	Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.	got7fsn_ti	CAAX farnesyltransferase activity|protein-cysteine farnesyltransferase activity|farnesyl-diphosphate:protein-cysteine farnesyltransferase activity|FTase activity				The catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein.  There is no relationship between this activity and farnesyltransferase activity, GO:0004311, where the catalyzed reaction forms (free) geranylgeranyl diphosphate.						GO:0018223	Reactome:R-HSA-9647978|Reactome:R-HSA-2530501|RHEA:13345|MetaCyc:2.5.1.58-RXN|EC:2.5.1.58		molecular_function											owl:Class	
GO:0140590	biolink:NamedThing	effector-mediated suppression of host defenses	A process mediated by a molecule secreted by a symbiont that results in the supression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	effector-mediated suppression of host defenses by symbiont	https://github.com/geneontology/go-ontology/issues/20813					pg	2021-02-08T07:26:05Z						biological_process											owl:Class	
GO:0071024	biolink:NamedThing	SL snRNP	A ribonucleoprotein complex that contains spliced leader (SL) RNA and associated proteins.	got7fsn_ti							mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0042126	biolink:NamedThing	nitrate metabolic process	The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid.	got7fsn_ti	nitrate metabolism													biological_process											owl:Class	
GO:0003033	biolink:NamedThing	detection of hypoxic conditions in blood by aortic body chemoreceptor signaling	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.	got7fsn_ti	detection of hypoxic conditions in blood by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0002007	biolink:NamedThing	detection of hypoxic conditions in blood by chemoreceptor signaling	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.	got7fsn_ti	detection of hypoxic conditions in blood by chemoreceptor signalling													biological_process											owl:Class	
GO:0016661	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors											EC:1.7.-.-		molecular_function											owl:Class	
GO:0032143	biolink:NamedThing	single thymine insertion binding	Binding to a double-stranded DNA region containing a single thymine insertion or a deletion that results in an unpaired thymine.	got7fsn_ti														molecular_function											owl:Class	
GO:0102308	biolink:NamedThing	erythromycin D 3''-o-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + erythromycin D <=> S-adenosyl-L-homocysteine  + erythromycin B + H+.	got7fsn_ti												EC:2.1.1.254|MetaCyc:RXN-12924|RHEA:32651		molecular_function											owl:Class	
GO:0032517	biolink:NamedThing	SOD1-calcineurin complex	A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1.	got7fsn_ti														cellular_component											owl:Class	
GO:0008327	biolink:NamedThing	methyl-CpG binding	Binding to a methylated cytosine/guanine dinucleotide.	got7fsn_ti														molecular_function											owl:Class	
GO:0050741	biolink:NamedThing	protein-FMN linkage via O3-riboflavin phosphoryl-L-serine	The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-serine.	got7fsn_ti												RESID:AA0350		biological_process											owl:Class	
GO:0004757	biolink:NamedThing	sepiapterin reductase activity	Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+.	got7fsn_ti	7,8-dihydrobiopterin:NADP+ oxidoreductase activity											MetaCyc:SEPIAPTERIN-REDUCTASE-RXN|RHEA:18953|Reactome:R-HSA-1497869|EC:1.1.1.153|Reactome:R-HSA-1475414		molecular_function											owl:Class	
GO:0047927	biolink:NamedThing	gibberellin-44 dioxygenase activity	Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2.	got7fsn_ti	(gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase activity|oxygenase, gibberellin A44 oxidase activity|gibberellin A44 oxidase activity|(gibberellin-44),2-oxoglutarate:oxygen oxidoreductase activity											EC:1.14.11.12|MetaCyc:RXN1F-168|RHEA:16033		molecular_function											owl:Class	
GO:0050964	biolink:NamedThing	detection of electrical stimulus involved in electroception	The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal.	got7fsn_ti	detection of electrical stimulus during electroreception|electroception, detection of electrical stimulus|sensory transduction of electrical stimulus during electroception|electroception, sensory transduction of electrical stimulus|electroception, sensory detection of electrical stimulus|electroception, sensory transduction|sensory detection of electrical stimulus during electroception													biological_process											owl:Class	
GO:0061132	biolink:NamedThing	pancreas induction	The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas.	got7fsn_ti							dph	2010-05-17T09:45:32Z						biological_process											owl:Class	
GO:0042118	biolink:NamedThing	endothelial cell activation	The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti														biological_process											owl:Class	
GO:1903143	biolink:NamedThing	adrenomedullin receptor complex	A transmembrane, G protein-coupled signalling receptor complex which is capable of adrenomedullin receptor activity.	got7fsn_ti	adrenomedullin receptor AM1 complex|adrenomedullin receptor AM2 complex				An example of this is RAMP2 in human (O60895) in PMID:22102369 (inferred from direct assay).		bhm	2014-07-02T08:56:47Z						cellular_component											owl:Class	
GO:0038037	biolink:NamedThing	G protein-coupled receptor dimeric complex	A protein complex that contains two G protein-coupled receptors.	got7fsn_ti	GPCR dimer|G-protein coupled receptor dimer|G-protein coupled receptor dimeric complex						bf	2011-11-02T04:42:44Z						cellular_component											owl:Class	
GO:0043015	biolink:NamedThing	gamma-tubulin binding	Binding to the microtubule constituent protein gamma-tubulin.	got7fsn_ti	gamma tubulin binding													molecular_function											owl:Class	
GO:0015631	biolink:NamedThing	tubulin binding	Binding to monomeric or multimeric forms of tubulin, including microtubules.	got7fsn_ti														molecular_function											owl:Class	
GO:0044358	biolink:NamedThing	envenomation resulting in hemorrhagic damage to other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism.	got7fsn_ti							jl	2011-10-26T04:24:59Z						biological_process											owl:Class	
GO:0038179	biolink:NamedThing	neurotrophin signaling pathway	A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.	got7fsn_ti	neurotrophin receptor signaling pathway				There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors.		bf	2013-03-27T17:22:44Z						biological_process											owl:Class	
GO:0035107	biolink:NamedThing	appendage morphogenesis	The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.	got7fsn_ti														biological_process											owl:Class	
GO:1902432	biolink:NamedThing	protein localization to division septum	A process in which a protein is transported to, or maintained in, a location within a division septum.	got7fsn_ti	protein localization in division septum|protein localisation to division septum|protein localisation in division septum						mah	2013-09-30T14:29:51Z						biological_process											owl:Class	
GO:0046951	biolink:NamedThing	ketone body biosynthetic process	The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.	got7fsn_ti	ketone body biosynthesis|ketone body synthesis|ketone body anabolism|ketone body formation													biological_process											owl:Class	
GO:0042381	biolink:NamedThing	hemolymph coagulation	Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.	got7fsn_ti	hemolymph clotting													biological_process											owl:Class	
GO:0007599	biolink:NamedThing	hemostasis	The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.	got7fsn_ti												Wikipedia:Hemostasis		biological_process											owl:Class	
GO:0034521	biolink:NamedThing	1-naphthoic acid dioxygenase activity	Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+.	got7fsn_ti												EC:1.14.12.-|UM-BBD_reactionID:r0773		molecular_function											owl:Class	
GO:0071617	biolink:NamedThing	lysophospholipid acyltransferase activity	Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid.	got7fsn_ti							mah	2010-02-08T04:53:37Z						molecular_function											owl:Class	
GO:0062011	biolink:NamedThing	mitochondrial respiratory chain complex IV pre-assembly complex	A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components.	got7fsn_ti	COX1 preassemply complex|COX pre-assemply complex						dph	2018-02-28T14:50:26Z						cellular_component											owl:Class	
GO:0101031	biolink:NamedThing	chaperone complex	A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.	got7fsn_ti					An example of this is HSP90AB1 in human (P08238) in PMID:21855797 (inferred from direct assay).									cellular_component											owl:Class	
GO:0015190	biolink:NamedThing	L-leucine transmembrane transporter activity	Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid.	got7fsn_ti	L-leucine transporter activity|leucine/valine/isoleucine permease activity|leucine/isoleucine/valine porter activity													molecular_function											owl:Class	
GO:0050890	biolink:NamedThing	cognition	The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.	got7fsn_ti												Wikipedia:Cognition		biological_process											owl:Class	
GO:0098819	biolink:NamedThing	depolarization of postsynaptic membrane	A process that depolarizes a postsynaptic membrane relative to its resting potential.  This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold.	got7fsn_ti														biological_process											owl:Class	
GO:0060078	biolink:NamedThing	regulation of postsynaptic membrane potential	Any process that modulates the potential difference across a post-synaptic membrane.	got7fsn_ti	regulation of post-synaptic membrane potential													biological_process											owl:Class	
GO:0005212	biolink:NamedThing	structural constituent of eye lens	The action of a molecule that contributes to the structural integrity of the lens of an eye.	got7fsn_ti														molecular_function											owl:Class	
GO:0043820	biolink:NamedThing	propionyl-CoA dehydrogenase activity	Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA.	got7fsn_ti												EC:1.3.99.-		molecular_function											owl:Class	
GO:1990064	biolink:NamedThing	ground tissue pattern formation	The regionalization process that gives rise to the patterning of the ground tissue.	got7fsn_ti	ground tissue patterning						tb	2013-03-21T23:24:44Z						biological_process											owl:Class	
GO:1990212	biolink:NamedThing	positive regulation by symbiont of ethylene levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-09T19:03:10Z						biological_process											owl:Class	
GO:0052024	biolink:NamedThing	positive regulation by symbiont of hormone or growth regulator levels in host	The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	upregulation by symbiont of hormone or growth regulator levels in host|stimulation by symbiont of hormone or growth regulator levels in host|activation by symbiont of hormone or growth regulator levels in host|up-regulation by symbiont of hormone or growth regulator levels in host|positive modulation of hormone or growth regulator levels in host|positive regulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction|up regulation by symbiont of hormone or growth regulator levels in host										GO:0052513			biological_process											owl:Class	
GO:0035458	biolink:NamedThing	cellular response to interferon-beta	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.	got7fsn_ti	cellular response to beta-1 interferon|cellular response to fibroblast interferon|cellular response to fiblaferon						bf	2010-04-16T11:10:40Z						biological_process											owl:Class	
GO:0035070	biolink:NamedThing	salivary gland histolysis	The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.	got7fsn_ti	salivary gland regression													biological_process											owl:Class	
GO:0016796	biolink:NamedThing	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.	got7fsn_ti	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5' phosphomonoesters				Note that this activity can catalyze cleavage of DNA or RNA.							EC:3.1.15.-		molecular_function											owl:Class	
GO:0030892	biolink:NamedThing	mitotic cohesin complex	A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0008278	biolink:NamedThing	cohesin complex	A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).	got7fsn_ti	cohesin core heterodimer|14S cohesin|SMC/kleisin ring complex|9S cohesin|SMC complex|Smc1-Smc3 complex										GO:0008280|GO:0043222|GO:0008279			cellular_component											owl:Class	
GO:0090700	biolink:NamedThing	maintenance of plant organ identity	The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti							tb	2016-08-29T15:01:08Z						biological_process											owl:Class	
GO:0035944	biolink:NamedThing	perforin production	The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-07-27T11:44:21Z						biological_process											owl:Class	
GO:0043228	biolink:NamedThing	non-membrane-bounded organelle	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.	got7fsn_ti	biological condensate|non-membrane-enclosed organelle	https://github.com/geneontology/go-ontology/issues/21881										NIF_Subcellular:sao1456184038		cellular_component											owl:Class	
GO:0019629	biolink:NamedThing	propionate catabolic process, 2-methylcitrate cycle	The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.	got7fsn_ti	propionate degradation, 2-methylcitrate cycle|propionate breakdown, 2-methylcitrate cycle													biological_process											owl:Class	
GO:0019543	biolink:NamedThing	propionate catabolic process	The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.	got7fsn_ti	propionate breakdown|propionate catabolism|propionate degradation													biological_process											owl:Class	
GO:0031579	biolink:NamedThing	membrane raft organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	got7fsn_ti	lipid raft organization|membrane raft organization and biogenesis|membrane raft organisation													biological_process											owl:Class	
GO:0014028	biolink:NamedThing	notochord formation	The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.	got7fsn_ti														biological_process											owl:Class	
GO:0000953	biolink:NamedThing	branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.	got7fsn_ti	branched chain family amino acid catabolic process to carboxylic acid via Ehrlich pathway													biological_process											owl:Class	
GO:0009932	biolink:NamedThing	cell tip growth	Growth that occurs specifically at the tip of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0062200	biolink:NamedThing	RAM/MOR signaling pathway	An intracellular signaling pathway that regulates interphase polarized growth and cell separation at the end of cytokinesis through activation of the NDR1/2-related kinase.	got7fsn_ti	morphogenesis Orb6 network|RAM signaling pathway|MOR signaling pathway						dph	2019-12-17T20:21:12Z						biological_process											owl:Class	
GO:1900030	biolink:NamedThing	regulation of pectin biosynthetic process	Any process that modulates the frequency, rate or extent of pectin biosynthetic process.	got7fsn_ti	regulation of pectin biosynthesis|regulation of pectin formation|regulation of pectin anabolism|regulation of pectin synthesis						tb	2012-01-13T02:03:37Z						biological_process											owl:Class	
GO:0015183	biolink:NamedThing	L-aspartate transmembrane transporter activity	Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.	got7fsn_ti	glutamate/aspartate:sodium symporter activity|L-aspartate transporter activity|glutamate/aspartate porter activity													molecular_function											owl:Class	
GO:0015172	biolink:NamedThing	acidic amino acid transmembrane transporter activity	Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.	got7fsn_ti	acidic amino acid transporter activity											Reactome:R-HSA-372448		molecular_function											owl:Class	
GO:0031797	biolink:NamedThing	type 2 metabotropic GABA receptor binding	Binding to a type 2 metabotropic GABA receptor.	got7fsn_ti	type 2 metabotropic GABA receptor ligand													molecular_function											owl:Class	
GO:0031795	biolink:NamedThing	G protein-coupled GABA receptor binding	Binding to a G protein-coupled (metabotropic) GABA receptor.	got7fsn_ti	G-protein coupled GABA receptor binding|GABAB receptor binding|metabotropic GABA receptor binding|metabotropic GABA receptor ligand													molecular_function											owl:Class	
GO:0052843	biolink:NamedThing	inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity	Catalysis of the reaction: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.	got7fsn_ti							ai	2011-12-05T10:42:00Z				MetaCyc:RXN-10977		molecular_function											owl:Class	
GO:0061622	biolink:NamedThing	glycolytic process through glucose-1-phosphate	The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.	got7fsn_ti							dph	2014-04-28T08:08:01Z						biological_process											owl:Class	
GO:0097256	biolink:NamedThing	phenyllactate dehydrogenase activity	Catalysis of the reaction: (R)-3-phenyllactate + NAD+ = 3-phenylpyruvate + H+ + NADH.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21412			This enzymatic activity is usually negligible, but may become prominent when phenylalanine levels are abnormally high as in the human disease phenylketonuria (PKU).		pr	2012-03-07T11:39:39Z				RHEA:38351|EC:1.1.1.110		molecular_function											owl:Class	
GO:0048575	biolink:NamedThing	short-day photoperiodism, flowering	A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length.	got7fsn_ti	short-day photoperiodic control of flowering|short-day photoperiodic control of flowering time|long-night photoperiodism, flowering|short-day photoperiodic control of inflorescence development|response to long-night, flowering|response to short-day, flowering													biological_process											owl:Class	
GO:0048573	biolink:NamedThing	photoperiodism, flowering	A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species.	got7fsn_ti	response to photoperiod, flowering|response to night length, flowering|photoperiodic control of flowering time|photoperiodic control of inflorescence development|response to day length, flowering													biological_process											owl:Class	
GO:0034499	biolink:NamedThing	late endosome to Golgi transport	The directed movement of substances from late endosomes to the Golgi.	got7fsn_ti	prevacuolar endosome to Golgi transport|PVE to Golgi transport													biological_process											owl:Class	
GO:0033746	biolink:NamedThing	histone H3-methyl-arginine-2 demethylase activity	Catalysis of the removal of the methyl group from a modified arginine residue at position 2 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone H3R2me demethylase activity|histone demethylase activity (H3-R2 specific)	https://github.com/geneontology/go-ontology/issues/21089												molecular_function											owl:Class	
GO:0046678	biolink:NamedThing	response to bacteriocin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.	got7fsn_ti	bacteriocin susceptibility/resistance													biological_process											owl:Class	
GO:0103037	biolink:NamedThing	L-glyceraldehyde 3-phosphate reductase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH.	got7fsn_ti												MetaCyc:RXN0-5410		molecular_function											owl:Class	
GO:0120208	biolink:NamedThing	telodendria	Telodendria are projections that originate from the axon pedicle and form gap junctions with other neurons.	got7fsn_ti							krc	2019-05-20T23:50:28Z						cellular_component											owl:Class	
GO:0036086	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter in response to iron deficiency						bf	2012-01-05T01:45:26Z						biological_process											owl:Class	
GO:0033217	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter in response to iron deficiency													biological_process											owl:Class	
GO:0018828	biolink:NamedThing	halohydrin hydrogen-halide-lyase A activity	Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane.	got7fsn_ti												UM-BBD_enzymeID:e0048		molecular_function											owl:Class	
GO:0019181	biolink:NamedThing	halohydrin hydrogen-halide-lyase activity	Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide.	got7fsn_ti														molecular_function											owl:Class	
GO:0090294	biolink:NamedThing	nitrogen catabolite activation of transcription	A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.	got7fsn_ti	positive regulation of transcription by nitrogen catabolites						tb	2010-02-24T02:31:53Z						biological_process											owl:Class	
GO:0033403	biolink:NamedThing	UUA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UUA codon.	got7fsn_ti	leucine tRNA|TTA codon-amino acid adaptor activity				Note that in the standard genetic code, TTA codes for leucine.									molecular_function											owl:Class	
GO:0030869	biolink:NamedThing	RENT complex	A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit.	got7fsn_ti														cellular_component											owl:Class	
GO:0005677	biolink:NamedThing	chromatin silencing complex	Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.	got7fsn_ti														cellular_component											owl:Class	
GO:0035366	biolink:NamedThing	negative regulation of thymine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	negative regulation of 5-methyluracil transport						bf	2010-03-11T10:23:42Z						biological_process											owl:Class	
GO:0032240	biolink:NamedThing	negative regulation of nucleobase-containing compound transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport													biological_process											owl:Class	
GO:0034299	biolink:NamedThing	reproductive blastospore formation	The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota.	got7fsn_ti	blastoconidium formation				Note that this term should not be confused with the usage of 'blastospore' to mean any yeast-form fungal cell, as in Candida species.									biological_process											owl:Class	
GO:0048315	biolink:NamedThing	conidium formation	The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	got7fsn_ti	conidia biosynthesis|conidia formation													biological_process											owl:Class	
GO:0030766	biolink:NamedThing	11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.	got7fsn_ti	11-demethyl-17-deacetylvindoline 11-methyltransferase activity|S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase activity|tabersonine 16-O-methyltransferase activity|S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase activity											RHEA:20992|EC:2.1.1.94|MetaCyc:2.1.1.94-RXN		molecular_function											owl:Class	
GO:0097351	biolink:NamedThing	toxin sequestering activity	Binding to a toxic protein, disabling its function. There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other.	got7fsn_ti	toxin-antitoxin pair type I binding|toxin-antitoxin pair type II binding						pr	2012-06-28T11:41:38Z						molecular_function											owl:Class	
GO:0047470	biolink:NamedThing	(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity	Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside.	got7fsn_ti	(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase|malto-oligosyltrehalose synthase activity|maltodextrin alpha-D-glucosyltransferase activity											RHEA:13621|MetaCyc:5.4.99.15-RXN|EC:5.4.99.15		molecular_function											owl:Class	
GO:0061402	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter in response to acidity						dph	2012-01-10T03:06:32Z						biological_process											owl:Class	
GO:0071468	biolink:NamedThing	cellular response to acidic pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti	cellular response to acidity				This term should be used to annotate instances where a cell is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0071229 'cellular response to acid chemical'.		mah	2009-12-18T11:42:35Z						biological_process											owl:Class	
GO:0070537	biolink:NamedThing	histone H2A K63-linked deubiquitination	A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.	got7fsn_ti														biological_process											owl:Class	
GO:0070536	biolink:NamedThing	protein K63-linked deubiquitination	A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0071406	biolink:NamedThing	cellular response to methylmercury	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.	got7fsn_ti	cellular response to MeHg+|cellular response to CH3-Hg+						mah	2009-12-14T02:55:12Z						biological_process											owl:Class	
GO:0051597	biolink:NamedThing	response to methylmercury	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.	got7fsn_ti	response to CH3-Hg+|response to MeHg+													biological_process											owl:Class	
GO:0097229	biolink:NamedThing	sperm end piece	The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane.	got7fsn_ti							pr	2012-01-25T01:29:04Z						cellular_component											owl:Class	
GO:0120202	biolink:NamedThing	rod photoreceptor disc membrane	Stack of disc membranes located inside a rod photoreceptor outer segment, and containing densely packed molecules of rhodopsin photoreceptor proteins that traverse the lipid bilayer. It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment.	got7fsn_ti							krc	2019-05-07T23:27:06Z						cellular_component											owl:Class	
GO:0050009	biolink:NamedThing	isopropanol dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + propan-2-ol = acetone + H(+) + NADPH.	got7fsn_ti	propan-2-ol:NADP+ oxidoreductase activity											RHEA:21792|MetaCyc:ISOPROPANOL-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.80|KEGG_REACTION:R01550		molecular_function											owl:Class	
GO:0047178	biolink:NamedThing	glycerophospholipid acyltransferase (CoA-dependent) activity	Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine.	got7fsn_ti	1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine acyltransferase (CoA-dependent)											MetaCyc:2.3.1.148-RXN|EC:2.3.1.148|RHEA:20972		molecular_function											owl:Class	
GO:0034274	biolink:NamedThing	Atg12-Atg5-Atg16 complex	A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.	got7fsn_ti														cellular_component											owl:Class	
GO:0045787	biolink:NamedThing	positive regulation of cell cycle	Any process that activates or increases the rate or extent of progression through the cell cycle.	got7fsn_ti	up regulation of progression through cell cycle|activation of progression through cell cycle|positive regulation of progression through cell cycle|upregulation of progression through cell cycle|stimulation of progression through cell cycle|positive regulation of cell cycle progression|up-regulation of progression through cell cycle													biological_process											owl:Class	
GO:0060908	biolink:NamedThing	plasmid copy number maintenance	The maintenance of the number of copies of extrachromosomal plasmid DNA.	got7fsn_ti							dph	2009-09-04T02:49:08Z						biological_process											owl:Class	
GO:0006276	biolink:NamedThing	plasmid maintenance	The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0033645	biolink:NamedThing	host cell endomembrane system	A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														cellular_component											owl:Class	
GO:0008568	biolink:NamedThing	microtubule-severing ATPase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.	got7fsn_ti	katanin activity|ATP phosphohydrolase (tubulin-dimerizing)				See also the cellular component term 'katanin complex ; GO:0008352'.							EC:5.6.1.1|Reactome:R-HSA-9668419|MetaCyc:3.6.4.3-RXN		molecular_function											owl:Class	
GO:0043654	biolink:NamedThing	recognition of apoptotic cell	The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis.	got7fsn_ti	detection of apoptotic cell|detection of apoptotic cell corpse|recognition of cell corpse|recognition of apoptotic cell corpse|detection of cell corpse													biological_process											owl:Class	
GO:0006910	biolink:NamedThing	phagocytosis, recognition	The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.	got7fsn_ti	recognition of phagocytosed substance by phagocytic cell				Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.									biological_process											owl:Class	
GO:0033795	biolink:NamedThing	betaine reductase activity	Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin.	got7fsn_ti	acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) activity											EC:1.21.4.4|RHEA:11848		molecular_function											owl:Class	
GO:0050485	biolink:NamedThing	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide.	got7fsn_ti	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulphide as acceptor											EC:1.21.4.-		molecular_function											owl:Class	
GO:0000161	biolink:NamedThing	osmosensory signaling MAPK cascade	A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K.	got7fsn_ti	osmolarity sensing, activation of MAPKKK activity|activation of MAPKKK activity involved in osmosensory signaling pathway|Hog1 MAPK pathway|inactivation of MAPK activity involved in osmosensory signaling pathway|termination of MAPK activity during osmolarity sensing|osmolarity sensing, MAPKKK cascade|MAPKKK cascade involved in osmosensory signalling pathway|activation of MAPK activity involved in osmosensory signaling pathway|High Osmolarity Glycerol (HOG) MAPK pathway|MAPK cascade involved in osmosensory signaling pathway|activation of MAPKKK activity during osmolarity sensing|osmolarity sensing, activation of MAP kinase kinase kinase activity|activation of MAPKK activity during osmolarity sensing|activation of Pbs2 kinase|osmolarity sensing, activation of MAP kinase kinase activity|MAPKKK cascade involved in osmosensory signaling pathway|osmolarity sensing, activation of MAPK activity|activation of MAPKK activity involved in osmosensory signaling pathway|MAPKKK cascade during osmolarity sensing|Hog1/Sty1 stress-activated MAPK cascade|osmolarity sensing, activation of MAPKK activity	https://github.com/geneontology/go-ontology/issues/20380									GO:0000173|GO:0000167|GO:0000168|GO:0000169|GO:0007233			biological_process											owl:Class	
GO:0007231	biolink:NamedThing	osmosensory signaling pathway	The series of molecular signals initiated in response to osmotic change.	got7fsn_ti	osmolarity sensing signalling pathway|osmolarity sensing|signal transduction during osmotic stress|osmolarity sensing signaling pathway|osmosensory signalling pathway|osmosensory signal transduction	https://github.com/geneontology/go-ontology/issues/20368												biological_process											owl:Class	
GO:0019900	biolink:NamedThing	kinase binding	Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.	got7fsn_ti														molecular_function											owl:Class	
GO:0051216	biolink:NamedThing	cartilage development	The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	got7fsn_ti	cartilage formation|chondrogenesis|cartilage organ development|cartilage biosynthesis|cartilage element development|cartilage biogenesis											Wikipedia:Chondrogenesis		biological_process											owl:Class	
GO:0047262	biolink:NamedThing	polygalacturonate 4-alpha-galacturonosyltransferase activity	Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.	got7fsn_ti	uridine diphosphogalacturonate-polygalacturonate alpha-galacturonosyltransferase activity|UDP galacturonate-polygalacturonate alpha-galacturonosyltransferase activity|UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase activity										GO:0050375	EC:2.4.1.43|MetaCyc:2.4.1.43-RXN|RHEA:13573		molecular_function											owl:Class	
GO:0097298	biolink:NamedThing	regulation of nucleus size	Any process that modulates the size of the nucleus.	got7fsn_ti	regulation of nuclear size|regulation of nuclear volume						pr	2012-05-03T06:21:43Z						biological_process											owl:Class	
GO:0090714	biolink:NamedThing	innate immunity memory response	An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus.	got7fsn_ti							tb	2016-11-11T12:23:03Z						biological_process											owl:Class	
GO:0070696	biolink:NamedThing	transmembrane receptor protein serine/threonine kinase binding	Binding to a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.	got7fsn_ti							mah	2009-06-04T03:57:42Z						molecular_function											owl:Class	
GO:0002946	biolink:NamedThing	tRNA C5-cytosine methylation	The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.	got7fsn_ti	tRNA 5-methylcytosine biosynthesis						hjd	2012-12-07T14:23:13Z						biological_process											owl:Class	
GO:0042492	biolink:NamedThing	gamma-delta T cell differentiation	The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.	got7fsn_ti	gamma-delta T-cell differentiation|gamma-delta T-lymphocyte differentiation|gamma-delta T lymphocyte differentiation|gamma-delta T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0030653	biolink:NamedThing	beta-lactam antibiotic metabolic process	The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.	got7fsn_ti	beta-lactam antibiotic metabolism													biological_process											owl:Class	
GO:0072338	biolink:NamedThing	cellular lactam metabolic process	The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	got7fsn_ti	cellular lactam metabolism						mah	2010-11-04T04:31:21Z						biological_process											owl:Class	
GO:0060157	biolink:NamedThing	urinary bladder development	The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion.	got7fsn_ti														biological_process											owl:Class	
GO:0043407	biolink:NamedThing	negative regulation of MAP kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.	got7fsn_ti	inhibition of MAPK activity|down-regulation of MAPK activity|downregulation of MAPK activity|down regulation of MAPK activity|negative regulation of mitogen-activated protein kinase activity|negative regulation of mitogen activated protein kinase activity													biological_process											owl:Class	
GO:0061897	biolink:NamedThing	all-trans retinal 3,4-desaturase activity	Catalysis of the reaction: all-trans-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin].	got7fsn_ti							dph	2017-06-12T14:56:58Z						molecular_function											owl:Class	
GO:0014899	biolink:NamedThing	cardiac muscle atrophy	A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation.	got7fsn_ti														biological_process											owl:Class	
GO:0009765	biolink:NamedThing	photosynthesis, light harvesting	Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers.	got7fsn_ti	energy dissipation													biological_process											owl:Class	
GO:0045844	biolink:NamedThing	positive regulation of striated muscle tissue development	Any process that activates or increases the frequency, rate or extent of striated muscle development.	got7fsn_ti	up-regulation of striated muscle development|activation of striated muscle development|stimulation of striated muscle development|upregulation of striated muscle development|up regulation of striated muscle development													biological_process											owl:Class	
GO:0048636	biolink:NamedThing	positive regulation of muscle organ development	Any process that activates, maintains or increases the rate of muscle development.	got7fsn_ti	up regulation of muscle development|up-regulation of muscle development|upregulation of muscle development|activation of muscle development|stimulation of muscle development													biological_process											owl:Class	
GO:0071599	biolink:NamedThing	otic vesicle development	The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.	got7fsn_ti							mah	2010-02-04T04:07:17Z						biological_process											owl:Class	
GO:0051683	biolink:NamedThing	establishment of Golgi localization	The directed movement of the Golgi to a specific location.	got7fsn_ti	establishment of Golgi body localization|establishment of Golgi apparatus localization|establishment of Golgi localisation													biological_process											owl:Class	
GO:0031076	biolink:NamedThing	embryonic camera-type eye development	The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.	got7fsn_ti	embryonic eye development													biological_process											owl:Class	
GO:0106117	biolink:NamedThing	acidocalcisome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.	got7fsn_ti	acidocalcisome organisation|volutin granule organization|polyphosphate vacuole organization|acidocalcisome organization and biogenesis|metachromatic granule organization|acidocalcisome biogenesis						hjd	2018-04-19T17:18:01Z						biological_process											owl:Class	
GO:0071946	biolink:NamedThing	cis-acting DNA replication termination	A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.	got7fsn_ti	cis acting DNA replication termination						mah	2010-10-06T01:08:48Z						biological_process											owl:Class	
GO:0046945	biolink:NamedThing	N-terminal peptidyl-alanine N-carbamoylation	The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine.	got7fsn_ti	N-terminal peptidyl-alanine N-carbamylation											RESID:AA0343		biological_process											owl:Class	
GO:0033934	biolink:NamedThing	glucan 1,4-alpha-maltotriohydrolase activity	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.	got7fsn_ti	1,4-alpha-D-glucan maltotriohydrolase activity|exo-maltotriohydrolase activity|maltotriohydrolase activity											MetaCyc:3.2.1.116-RXN|EC:3.2.1.116		molecular_function											owl:Class	
GO:0052876	biolink:NamedThing	methylamine dehydrogenase (amicyanin) activity	Catalysis of the reaction: 2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H+ + NH4+ + 2 reduced [amicyanin].	got7fsn_ti	primary-amine dehydrogenase|methylamine:amicyanin oxidoreductase (deaminating) activity|methylamine dehydrogenase activity|amine dehydrogenase|MADH activity	https://github.com/geneontology/go-ontology/issues/21650										RHEA:30207|KEGG_REACTION:R00606|UM-BBD_reactionID:r0075|EC:1.4.9.1		molecular_function											owl:Class	
GO:0090018	biolink:NamedThing	posterior neural plate formation	The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.	got7fsn_ti							tb	2009-07-29T11:32:08Z						biological_process											owl:Class	
GO:0033714	biolink:NamedThing	secondary-alcohol oxidase activity	Catalysis of the reaction: O(2) + secondary alcohol = H(2)O(2) + ketone.	got7fsn_ti	secondary-alcohol:oxygen oxidoreductase activity|secondary alcohol oxidase activity|polyvinyl alcohol oxidase activity											KEGG_REACTION:R02277|MetaCyc:SECONDARY-ALCOHOL-OXIDASE-RXN|EC:1.1.3.18|RHEA:23180		molecular_function											owl:Class	
GO:0097384	biolink:NamedThing	cellular lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells.	got7fsn_ti	cellular lipid synthesis|cellular lipid anabolism|cellular lipid biosynthesis|cellular lipid formation						pr	2012-10-16T16:47:09Z						biological_process											owl:Class	
GO:0098882	biolink:NamedThing	structural constituent of presynaptic active zone	The action of a molecule that contributes to the structural integrity of a presynaptic active zone.	got7fsn_ti	structural constituent of active zone													molecular_function											owl:Class	
GO:0010354	biolink:NamedThing	homogentisate prenyltransferase activity	Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0030308	biolink:NamedThing	negative regulation of cell growth	Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.	got7fsn_ti	inhibition of cell growth|down regulation of cell growth|downregulation of cell growth|down-regulation of cell growth													biological_process											owl:Class	
GO:0010234	biolink:NamedThing	anther wall tapetum cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	tapetal cell fate specification													biological_process											owl:Class	
GO:0047999	biolink:NamedThing	hyponitrite reductase activity	Catalysis of the reaction: 2 hydroxylamine + 2 NAD(+) = 2 H(+) + hyponitrous acid + 2 NADH.	got7fsn_ti	NADH2:hyponitrite oxidoreductase activity|NADH:hyponitrite oxidoreductase activity|hydroxylamine:NAD+ oxidoreductase activity											MetaCyc:HYPONITRITE-REDUCTASE-RXN|EC:1.7.1.5|KEGG_REACTION:R00023|RHEA:19337		molecular_function											owl:Class	
GO:0031326	biolink:NamedThing	regulation of cellular biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.	got7fsn_ti	regulation of cellular synthesis|regulation of cellular biosynthesis|regulation of cellular formation|regulation of cellular anabolism													biological_process											owl:Class	
GO:0010643	biolink:NamedThing	cell communication by chemical coupling	The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti														biological_process											owl:Class	
GO:0043783	biolink:NamedThing	oxidoreductase activity, acting on metal ions, flavin as acceptor	Catalysis of an oxidation-reduction in which the metal ion is reduced and flavin acts as an electron acceptor.	got7fsn_ti	oxidoreductase activity, oxidizing metal ions with flavin as acceptor|oxidoreductase activity, reducing metal ions, flavin as acceptor	https://github.com/geneontology/go-ontology/issues/20675|https://github.com/geneontology/go-ontology/issues/20682										EC:1.16.8.-		molecular_function											owl:Class	
GO:0016722	biolink:NamedThing	oxidoreductase activity, acting on metal ions	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.	got7fsn_ti	oxidoreductase activity, reducing metal ions|oxidoreductase activity, oxidizing metal ions	https://github.com/geneontology/go-ontology/issues/20675										EC:1.16.-.-|Reactome:R-HSA-917805		molecular_function											owl:Class	
GO:0034409	biolink:NamedThing	ascospore wall (1->3)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.	got7fsn_ti	ascospore wall 1,3-beta-glucan metabolic process|ascospore wall beta-1,3 glucan metabolism|ascospore wall 1,3-beta-D-glucan metabolic process|ascospore wall beta-1,3 glucan metabolic process|ascospore wall 1,3-beta-glucan metabolism													biological_process											owl:Class	
GO:0010344	biolink:NamedThing	seed oilbody biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination.	got7fsn_ti	seed oil body organization|spherosome biogenesis|oleosome biogenesis													biological_process											owl:Class	
GO:0070342	biolink:NamedThing	brown fat cell proliferation	The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.	got7fsn_ti	brown adipose cell proliferation|brown adipocyte proliferation													biological_process											owl:Class	
GO:0000720	biolink:NamedThing	pyrimidine dimer repair by nucleotide-excision repair	The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.	got7fsn_ti					Note that the repair of pyrimidine dimers by nucleotide excision repair involves the same gene products that are involved in general nucleotide excision repair. Consider also annotating to other children of the biological process term 'nucleotide-excision repair ; GO:0006289'.									biological_process											owl:Class	
GO:0006289	biolink:NamedThing	nucleotide-excision repair	A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).	got7fsn_ti	pyrimidine-dimer repair, DNA damage excision|NER|intrastrand cross-link repair				Note that although intrastrand cross-link repair is not exactly synonymous with nucleotide excision repair, nucleotide excision repair includes the repair of intrastrand cross-links. The synonym field is being used to reflect the broad substrate specificity of nucleotide excision repair.						GO:0045001			biological_process											owl:Class	
GO:0000837	biolink:NamedThing	Doa10p ubiquitin ligase complex	A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.	got7fsn_ti	Ssm4p ubiquitin ligase complex													cellular_component											owl:Class	
GO:0000835	biolink:NamedThing	ER ubiquitin ligase complex	A ubiquitin ligase complex found in the ER.	got7fsn_ti														cellular_component											owl:Class	
GO:0018788	biolink:NamedThing	atrazine chlorohydrolase activity	Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+).	got7fsn_ti	AtzA											MetaCyc:3.8.1.8-RXN|UM-BBD_reactionID:r0113|KEGG_REACTION:R05558|EC:3.8.1.8|RHEA:11312		molecular_function											owl:Class	
GO:0106157	biolink:NamedThing	peptidyl-arginine 3-dioxygenase activity	Catalyzes the reaction: 2-oxoglutarate + [protein]-L-arginine + O2 = [protein]-(3R)-3-hydroxy-L-arginine + CO2 + succinate.	got7fsn_ti	L-arginine 3-hydroxylase activity	https://github.com/geneontology/go-ontology/issues/16689					hjd	2018-11-26T15:05:57Z			GO:0140554	RHEA:56744		molecular_function											owl:Class	
GO:0001992	biolink:NamedThing	regulation of systemic arterial blood pressure by vasopressin	The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.	got7fsn_ti	blood pressure regulation by vasopressin|vasopressin control of blood pressure													biological_process											owl:Class	
GO:0031011	biolink:NamedThing	Ino80 complex	A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity.	got7fsn_ti	INO80 chromatin remodeling complex													cellular_component											owl:Class	
GO:0097346	biolink:NamedThing	INO80-type complex	A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair.	got7fsn_ti							pr	2012-06-20T11:26:55Z						cellular_component											owl:Class	
GO:0006024	biolink:NamedThing	glycosaminoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.	got7fsn_ti	glycosaminoglycan synthesis|glycosaminoglycan formation|glycosaminoglycan anabolism|glycosaminoglycan biosynthesis													biological_process											owl:Class	
GO:0030203	biolink:NamedThing	glycosaminoglycan metabolic process	The chemical reactions and pathways involving glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. Formerly known as mucopolysaccharides, they include hyaluronic acid and chondroitin, which provide lubrication in joints and form part of the matrix of cartilage. The three-dimensional structure of these molecules enables them to trap water, which forms a gel and gives glycosaminoglycans their elastic properties.	got7fsn_ti	glycosaminoglycan metabolism													biological_process											owl:Class	
GO:0002768	biolink:NamedThing	immune response-regulating cell surface receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.	got7fsn_ti	immune response-regulating cell surface receptor signalling pathway													biological_process											owl:Class	
GO:0032593	biolink:NamedThing	insulin-responsive compartment	A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.	got7fsn_ti	IRC|GSC|GLUT4 storage compartment													cellular_component											owl:Class	
GO:1900100	biolink:NamedThing	positive regulation of plasma cell differentiation	Any process that activates or increases the frequency, rate or extent of plasma cell differentiation.	got7fsn_ti	up regulation of plasma cell differentiation|up-regulation of plasma cell development|activation of plasma cell differentiation|up-regulation of plasma cell differentiation|upregulation of plasma cell differentiation|activation of plasma cell development|up regulation of plasma cell development|upregulation of plasma cell development|positive regulation of plasma cell development						bf	2012-02-15T10:46:08Z						biological_process											owl:Class	
GO:0070878	biolink:NamedThing	primary miRNA binding	Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.	got7fsn_ti	pri-miRNA binding|primary microRNA binding						mah	2009-08-20T04:11:36Z						molecular_function											owl:Class	
GO:0071694	biolink:NamedThing	maintenance of protein location in extracellular region	Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere.	got7fsn_ti							mah	2010-02-25T04:04:41Z						biological_process											owl:Class	
GO:0018508	biolink:NamedThing	cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+.	got7fsn_ti	benzoate cis-diol dehydrogenase activity											UM-BBD_enzymeID:e0219		molecular_function											owl:Class	
GO:0008084	biolink:NamedThing	imaginal disc growth factor receptor binding	Binding to an imaginal disc growth factor receptor.	got7fsn_ti	imaginal disc growth factor													molecular_function											owl:Class	
GO:0002355	biolink:NamedThing	detection of tumor cell	The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0052164	biolink:NamedThing	symbiont defense to host-produced reactive oxygen species	Any process in which a symbiont modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related host reactive oxygen intermediate production|modulation by organism of defense-related host oxidative burst|response to defense-related reactive oxygen species production by other organism involved in symbiotic interaction|evasion or tolerance of defense-related host oxidative burst|evasion or tolerance by organism of host-produced reactive oxygen species|evasion or tolerance by organism of reactive oxygen species produced during host defense response|evasion by symbiont of cellular damage caused by host oxidative burst|modulation by organism of defense-related host active oxygen species production|modulation by symbiont of defense-related host reactive oxygen species production|modulation by organism of defense-related host ROI production|evasion or tolerance by symbiont of host-produced reactive oxygen species|modulation by organism of defense-related host ROS production|evasion or tolerance of host-produced active oxygen species|evasion or tolerance of host-produced reactive oxygen intermediates|modulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|evasion or tolerance of reactive oxygen species produced by host|evasion or tolerance of host-produced ROIs|modulation by organism of defense-related host respiratory burst|modulation by organism of defense-related host metabolic burst|modulation by organism of defense-related host reactive oxidative species production|evasion or tolerance by organism of reactive oxygen species produced by other organism involved in symbiotic interaction|evasion or tolerance of host-produced ROS|evasion or tolerance by symbiont of reactive oxygen species produced by other organism involved in symbiotic interaction|evasion or tolerance of defense-related host metabolic burst|evasion or tolerance of defense-related host respiratory burst|modulation by organism of defense-related host AOS production|evasion or tolerance of host-produced AOS|response to defense-related host reactive oxygen species production	https://github.com/geneontology/go-ontology/issues/18697									GO:0052567|GO:0052303|GO:0052059|GO:0052550|GO:0052385			biological_process											owl:Class	
GO:0072244	biolink:NamedThing	metanephric glomerular epithelium development	The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	got7fsn_ti							mah	2010-03-19T03:38:47Z						biological_process											owl:Class	
GO:0072207	biolink:NamedThing	metanephric epithelium development	The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	got7fsn_ti							mah	2010-03-18T11:50:37Z						biological_process											owl:Class	
GO:0009922	biolink:NamedThing	fatty acid elongase activity	Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C).	got7fsn_ti												Reactome:R-HSA-548800|Reactome:R-HSA-548830|MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN|Reactome:R-HSA-2046094|Reactome:R-HSA-548815|Reactome:R-HSA-548814|Reactome:R-HSA-2046095|Reactome:R-HSA-2046090|Reactome:R-HSA-2046083|Reactome:R-HSA-2046100|Reactome:R-HSA-2046088		molecular_function											owl:Class	
GO:0007304	biolink:NamedThing	chorion-containing eggshell formation	The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.	got7fsn_ti	eggshell formation													biological_process											owl:Class	
GO:0030703	biolink:NamedThing	eggshell formation	Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.	got7fsn_ti														biological_process											owl:Class	
GO:0036172	biolink:NamedThing	thiamine salvage	A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.	got7fsn_ti							bf	2012-03-29T10:31:05Z				MetaCyc:PWY-6897|MetaCyc:PWY-6898|MetaCyc:PWY-6896		biological_process											owl:Class	
GO:0009228	biolink:NamedThing	thiamine biosynthetic process	The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.	got7fsn_ti	thiamine biosynthesis|vitamin B1 biosynthesis|thiamine formation|vitamin B1 biosynthetic process|thiamin anabolism|thiamine synthesis|thiamin biosynthetic process											MetaCyc:THISYN-PWY		biological_process											owl:Class	
GO:0098765	biolink:NamedThing	meiosis II cell cycle phase	A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).	got7fsn_ti					This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0010313	biolink:NamedThing	phytochrome binding	Binding to a phytochrome.	got7fsn_ti														molecular_function											owl:Class	
GO:0039579	biolink:NamedThing	suppression by virus of host ISG15 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 activity. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives.	got7fsn_ti							bf					VZ:723		biological_process											owl:Class	
GO:0039507	biolink:NamedThing	suppression by virus of host molecular function	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein.	got7fsn_ti	inhibition of host protein function|down-regulation by virus of host protein function|negative regulation by virus of host protein function|down regulation by virus of host protein function|inhibition by virus of host protein function|negative regulation by virus of host molecular function						bf	2011-06-02T02:47:03Z						biological_process											owl:Class	
GO:0009904	biolink:NamedThing	chloroplast accumulation movement	The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis.	got7fsn_ti	low-fluence-rate response													biological_process											owl:Class	
GO:0042976	biolink:NamedThing	activation of Janus kinase activity	The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.	got7fsn_ti	activation of JAK protein by tyrosine phosphorylation|tyrosine phosphorylation of JAK2 protein|tyrosine phosphorylation of JAK1 protein|tyrosine phosphorylation of JAK protein|activation of JAK1 protein|activation of JAK2 protein|activation of JAK1 kinase activity|positive regulation of JAK protein activity by tyrosine phosphorylation|activation of JAK2 kinase activity|activation of JAK protein										GO:0042977|GO:0010531			biological_process											owl:Class	
GO:0030163	biolink:NamedThing	protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	got7fsn_ti	pheromone catabolic process|protein catabolism|protein breakdown|pheromone catabolism|protein degradation|multicellular organismal protein catabolic process				This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children.						GO:0044254	Wikipedia:Protein_catabolism		biological_process											owl:Class	
GO:0005771	biolink:NamedThing	multivesicular body	A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.	got7fsn_ti	MVB|MVE|multivesicular endosome											NIF_Subcellular:sao2045955158		cellular_component											owl:Class	
GO:0005770	biolink:NamedThing	late endosome	A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.	got7fsn_ti	PVC|prevacuolar compartment											NIF_Subcellular:nlx_subcell_20090702		cellular_component											owl:Class	
GO:0015425	biolink:NamedThing	ATPase-coupled nonpolar-amino acid transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).	got7fsn_ti	leucine/isoleucine/valine porter activity|ATP-dependent nonpolar-amino acid transporter activity|nonpolar-amino acid-transporting ATPase activity|nonpolar-amino acid ABC transporter|nonpolar-amino-acid-transporting ATPase activity|nonpolar amino acid-transporting ATPase activity											MetaCyc:3.6.3.22-RXN|TC:3.A.1.4.1|EC:7.4.2.2		molecular_function											owl:Class	
GO:0016241	biolink:NamedThing	regulation of macroautophagy	Any process that modulates the frequency, rate or extent of macroautophagy.	got7fsn_ti	regulation of starvation-induced autophagy													biological_process											owl:Class	
GO:0003092	biolink:NamedThing	renal water retention	The process in which renal water excretion is decreased.	got7fsn_ti	negative regulation of renal water excretion													biological_process											owl:Class	
GO:0035811	biolink:NamedThing	negative regulation of urine volume	Any process that decreases the amount of urine excreted from the body over a unit of time.	got7fsn_ti	reduction of urinary volume|decrease in urine flow|antidiuresis						bf	2011-04-20T01:21:01Z						biological_process											owl:Class	
GO:0021705	biolink:NamedThing	locus ceruleus formation	The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.	got7fsn_ti														biological_process											owl:Class	
GO:0034614	biolink:NamedThing	cellular response to reactive oxygen species	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	got7fsn_ti	cellular response to ROS|cellular response to AOS|cellular response to reactive oxygen intermediate|cellular response to active oxygen species|cellular response to ROI|cellular response to reactive oxidative species													biological_process											owl:Class	
GO:0009378	biolink:NamedThing	four-way junction helicase activity	Unwinding a DNA helix of DNA containing four-way junctions, including Holliday junctions, driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent four-way junction helicase activity|Holliday junction helicase activity|ATP-dependent four-way junction DNA helicase activity|ATP-dependent Holliday junction helicase activity						pr	2013-08-07T13:36:54Z			GO:1990163			molecular_function											owl:Class	
GO:0033453	biolink:NamedThing	GCU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GCU codon.	got7fsn_ti	alanine tRNA|GCT codon-amino acid adaptor activity				Note that in the standard genetic code, GCT codes for alanine.									molecular_function											owl:Class	
GO:0010439	biolink:NamedThing	regulation of glucosinolate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.	got7fsn_ti														biological_process											owl:Class	
GO:0071829	biolink:NamedThing	plasma lipoprotein particle disassembly	The disaggregation of a plasma lipoprotein particle into its constituent components.	got7fsn_ti							mah	2010-09-08T11:14:21Z						biological_process											owl:Class	
GO:0071827	biolink:NamedThing	plasma lipoprotein particle organization	A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins.	got7fsn_ti	plasma lipoprotein particle organisation						mah	2010-09-08T10:32:26Z						biological_process											owl:Class	
GO:0047146	biolink:NamedThing	sterigmatocystin 7-O-methyltransferase activity	Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine.	got7fsn_ti	O-methyltransferase II activity|S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase activity|sterigmatocystin methyltransferase activity|S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase activity|sterigmatocystin 8-O-methyltransferase activity											RHEA:15561|EC:2.1.1.110|MetaCyc:2.1.1.110-RXN		molecular_function											owl:Class	
GO:1990948	biolink:NamedThing	ubiquitin ligase inhibitor activity	Binds to and stops, prevents or reduces the activity of a ubiquitin ligase.	got7fsn_ti	APC-Cdc20 complex inhibitor activity|mitotic anaphase-promoting complex inhibitor activity						vw	2016-04-21T16:36:54Z			GO:0061637|GO:0090645			molecular_function											owl:Class	
GO:0097250	biolink:NamedThing	mitochondrial respirasome assembly	The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex.	got7fsn_ti	mitochondrial respiratory chain supercomplex assembly|mitochondrial respiratory supercomplex assembly	https://github.com/geneontology/go-ontology/issues/12846					pr	2012-02-23T05:18:41Z						biological_process											owl:Class	
GO:0009440	biolink:NamedThing	cyanate catabolic process	The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid.	got7fsn_ti	cyanate degradation|cyanate breakdown|cyanate catabolism													biological_process											owl:Class	
GO:1901441	biolink:NamedThing	poly(hydroxyalkanoate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate).	got7fsn_ti	poly(hydroxyalkanoate) biosynthesis|poly(hydroxyalkanoate) formation|poly(hydroxyalkanoate) synthesis|poly(hydroxyalkanoate) anabolism						tt	2012-10-02T01:48:33Z						biological_process											owl:Class	
GO:0031583	biolink:NamedThing	phospholipase D-activating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA).	got7fsn_ti	activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway|phospholipase D-activating G-protein coupled receptor signaling pathway|G-protein signalling, phospholipase D activating pathway				This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase D (PLD) activation.									biological_process											owl:Class	
GO:0006627	biolink:NamedThing	protein processing involved in protein targeting to mitochondrion	The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.	got7fsn_ti	mitochondrial processing|mitochondrial protein processing during import													biological_process											owl:Class	
GO:0034982	biolink:NamedThing	mitochondrial protein processing	The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import.	got7fsn_ti	mitochondrial protein modification													biological_process											owl:Class	
GO:0038162	biolink:NamedThing	erythropoietin-mediated signaling pathway	A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	EPO-R signaling pathway|erythropoietin receptor signaling pathway						bf	2012-05-14T02:28:38Z						biological_process											owl:Class	
GO:0050744	biolink:NamedThing	protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine	The formation of a protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine.	got7fsn_ti												RESID:AA0353		biological_process											owl:Class	
GO:0036527	biolink:NamedThing	peptidyl-arginine deglycation	The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein.	got7fsn_ti	deglycation of N-acetylarginine						bf	2016-08-04T10:36:30Z						biological_process											owl:Class	
GO:0036525	biolink:NamedThing	protein deglycation	The removal of a sugar or dicarbonyl from a glycated protein.	got7fsn_ti	glycated protein repair				Glycation is a non enzymatic covalent addition of a sugar or dicarbonyl (methylglyoxal, glyoxal) to a protein. Deglycation repairs the glycated amino acids.		bf	2016-08-04T10:28:54Z						biological_process											owl:Class	
GO:0061735	biolink:NamedThing	DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization	A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule.	got7fsn_ti	dynamin-like protein-mediated stimulation of mitophagy in response to mitochondrial depolarization						dph	2015-09-14T14:00:43Z						biological_process											owl:Class	
GO:0098779	biolink:NamedThing	positive regulation of mitophagy in response to mitochondrial depolarization	Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.	got7fsn_ti	positive regulation of macromitophagy in response to mitochondrial depolarization													biological_process											owl:Class	
GO:2001154	biolink:NamedThing	regulation of glycolytic fermentation to ethanol	Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol.	got7fsn_ti	regulation of ethanol fermentation|regulation of glucose fermentation to ethanol						mcc	2011-10-27T02:39:00Z						biological_process											owl:Class	
GO:0035219	biolink:NamedThing	prothoracic disc development	Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle.	got7fsn_ti														biological_process											owl:Class	
GO:0031295	biolink:NamedThing	T cell costimulation	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.	got7fsn_ti	T-cell costimulation|T lymphocyte costimulation|T-cell co-stimulation|T cell co-stimulation|T-lymphocyte costimulation													biological_process											owl:Class	
GO:0002388	biolink:NamedThing	immune response in Peyer's patch	Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0002387	biolink:NamedThing	immune response in gut-associated lymphoid tissue	Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules.	got7fsn_ti	immune response in GALT													biological_process											owl:Class	
GO:0019456	biolink:NamedThing	L-cysteine catabolic process via cystine, using cysteine transaminase	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3).	got7fsn_ti	L-cysteine breakdown via cystine, using cysteine transaminase|L-cysteine degradation via cystine, using cysteine transaminase													biological_process											owl:Class	
GO:0043551	biolink:NamedThing	regulation of phosphatidylinositol 3-kinase activity	Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring.	got7fsn_ti	regulation of phosphoinositide 3-kinase activity													biological_process											owl:Class	
GO:0000145	biolink:NamedThing	exocyst	A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.	got7fsn_ti	Sec6/8 complex|exocyst complex											Wikipedia:Exocyst		cellular_component											owl:Class	
GO:0044560	biolink:NamedThing	envenomation resulting in modulation of ion channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism.	got7fsn_ti	envenomation resulting in regulation of ion channel activity in other organism						jl	2012-04-05T03:46:35Z						biological_process											owl:Class	
GO:0022855	biolink:NamedThing	protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	glucose PTS transporter activity													molecular_function											owl:Class	
GO:0008625	biolink:NamedThing	extrinsic apoptotic signaling pathway via death domain receptors	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	death receptor-mediated apoptosis|induction of apoptosis via death receptors|induction of apoptosis via death domain receptors				Gene products that may be annotated to this term include: 1) ligands such as FASL; 2) receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer); 3) signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Examples are TWEAK (TNF12) and FN14 (TNFRSF12A) (UniProt symbols O43508 and Q9NP84) in PMID:21525013.									biological_process											owl:Class	
GO:0043421	biolink:NamedThing	anthranilate catabolic process	The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate).	got7fsn_ti	2-aminobenzoate degradation|ortho-aminobenzoic acid catabolism|anthranilate breakdown|ortho-aminobenzoic acid catabolic process|2-aminobenzoate catabolic process|anthranilate degradation|anthranilic acid catabolic process|anthranilate catabolism|2-aminobenzoate catabolism|anthranilic acid catabolism|2-aminobenzoate breakdown										GO:0019259	MetaCyc:2AMINOBENZDEG-PWY		biological_process											owl:Class	
GO:0010103	biolink:NamedThing	stomatal complex morphogenesis	The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells.	got7fsn_ti														biological_process											owl:Class	
GO:1990612	biolink:NamedThing	Sad1-Kms1 LINC complex	A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair.	got7fsn_ti							jl	2015-01-20T13:10:49Z						cellular_component											owl:Class	
GO:0034993	biolink:NamedThing	meiotic nuclear membrane microtubule tethering complex	A nuclear membrane  protein complex  which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis.	got7fsn_ti	LINC complex|SUN-KASH complex|LInker of Nucleoskeleton and Cytoskeleton complex													cellular_component											owl:Class	
GO:0102783	biolink:NamedThing	beta-carotene oxygenase activity	Catalysis of the reaction: beta-carotene + 2 O2 = 2 beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.	got7fsn_ti												MetaCyc:RXN-7883		molecular_function											owl:Class	
GO:0000463	biolink:NamedThing	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0007096	biolink:NamedThing	regulation of exit from mitosis	Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.	got7fsn_ti														biological_process											owl:Class	
GO:1901990	biolink:NamedThing	regulation of mitotic cell cycle phase transition	Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.	got7fsn_ti	mitotic cell cycle control						jl	2013-03-19T16:14:38Z						biological_process											owl:Class	
GO:0047736	biolink:NamedThing	cellobiose epimerase activity	Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose.	got7fsn_ti	cellobiose 2-epimerase activity											EC:5.1.3.11|MetaCyc:CELLOBIOSE-EPIMERASE-RXN|RHEA:23384		molecular_function											owl:Class	
GO:0061439	biolink:NamedThing	kidney vasculature morphogenesis	The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.	got7fsn_ti							dph	2012-03-08T12:30:11Z						biological_process											owl:Class	
GO:0010437	biolink:NamedThing	9,10 (9', 10')-carotenoid-cleaving dioxygenase activity	Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond.	got7fsn_ti														molecular_function											owl:Class	
GO:0045902	biolink:NamedThing	negative regulation of translational fidelity	Any process that decreases the ability of the translational apparatus to interpret the genetic code.	got7fsn_ti	downregulation of translational fidelity|inhibition of translational fidelity|down-regulation of translational fidelity|down regulation of translational fidelity													biological_process											owl:Class	
GO:0017148	biolink:NamedThing	negative regulation of translation	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.	got7fsn_ti	protein biosynthetic process inhibitor activity|down-regulation of protein biosynthetic process|negative regulation of protein synthesis|downregulation of protein biosynthetic process|negative regulation of protein anabolism|down regulation of protein biosynthetic process|inhibition of protein biosynthetic process|negative regulation of protein biosynthetic process|negative regulation of protein formation|protein biosynthesis inhibitor activity|negative regulation of protein biosynthesis										GO:0016478			biological_process											owl:Class	
GO:0035089	biolink:NamedThing	establishment of apical/basal cell polarity	The specification and formation of the polarity of a cell along its apical/basal axis.	got7fsn_ti														biological_process											owl:Class	
GO:0036467	biolink:NamedThing	5-hydroxy-L-tryptophan decarboxylase activity	Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin.	got7fsn_ti	5-hydroxytryptophan decarboxylase activity						bf	2014-07-21T09:22:24Z				RHEA:18533		molecular_function											owl:Class	
GO:0004058	biolink:NamedThing	aromatic-L-amino-acid decarboxylase activity	Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.	got7fsn_ti	aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)|aromatic-L-amino-acid carboxy-lyase activity|tryptophan decarboxylase activity|L-DOPA decarboxylase activity|aromatic amino acid decarboxylase activity|5-hydroxytryptophan decarboxylase activity|DOPA decarboxylase activity|hydroxytryptophan decarboxylase activity										GO:0016400	EC:4.1.1.28|MetaCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN|Reactome:R-HSA-209859|Reactome:R-HSA-209924		molecular_function											owl:Class	
GO:0039573	biolink:NamedThing	suppression by virus of host complement activation	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase.	got7fsn_ti	inhibition of host complement activation by virus|inhibition of host complement cascade by virus|inhibition of host complement factors by virus						bf					VZ:811		biological_process											owl:Class	
GO:0043103	biolink:NamedThing	hypoxanthine salvage	Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis.	got7fsn_ti	guanine, xanthine and their nucleoside salvage|adenine, hypoxanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0043096	biolink:NamedThing	purine nucleobase salvage	Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis.	got7fsn_ti	purine base salvage													biological_process											owl:Class	
GO:0002442	biolink:NamedThing	serotonin secretion involved in inflammatory response	The regulated release of serotonin by a cell as part of an inflammatory response.	got7fsn_ti	serotonin release involved in inflammatory response|serotonin secretion involved in acute inflammatory response													biological_process											owl:Class	
GO:0021795	biolink:NamedThing	cerebral cortex cell migration	The orderly movement of cells from one site to another in the cerebral cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0080167	biolink:NamedThing	response to karrikin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants).	got7fsn_ti							dhl	2010-09-23T05:07:22Z						biological_process											owl:Class	
GO:0009628	biolink:NamedThing	response to abiotic stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.	got7fsn_ti	response to abiotic stress	https://github.com/geneontology/go-ontology/issues/16572			Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0009955	biolink:NamedThing	adaxial/abaxial pattern specification	The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.	got7fsn_ti	adaxial/abaxial pattern formation													biological_process											owl:Class	
GO:0015188	biolink:NamedThing	L-isoleucine transmembrane transporter activity	Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid.	got7fsn_ti	leucine/isoleucine/valine porter activity|isoleucine/valine:sodium symporter activity|leucine/valine/isoleucine permease activity|L-isoleucine transporter activity													molecular_function											owl:Class	
GO:0033598	biolink:NamedThing	mammary gland epithelial cell proliferation	The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	got7fsn_ti														biological_process											owl:Class	
GO:0003279	biolink:NamedThing	cardiac septum development	The progression of a cardiac septum over time, from its initial formation to the mature structure.	got7fsn_ti	heart septum development						dph	2009-10-20T09:45:13Z						biological_process											owl:Class	
GO:1903942	biolink:NamedThing	positive regulation of respiratory gaseous exchange	Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange.	got7fsn_ti	up-regulation of respiratory gaseous exchange|activation of respiratory gaseous exchange|upregulation of respiratory gaseous exchange|up regulation of respiratory gaseous exchange						sl	2015-02-17T20:26:35Z						biological_process											owl:Class	
GO:0015015	biolink:NamedThing	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization.	got7fsn_ti	heparan sulphate proteoglycan biosynthesis, enzymatic modification|heparan sulfate proteoglycan anabolism, enzymatic modification|heparan sulfate proteoglycan formation, enzymatic modification|heparan sulfate proteoglycan synthesis, enzymatic modification|heparin proteoglycan biosynthetic process, enzymatic modification|heparan sulphate proteoglycan biosynthetic process, enzymatic modification													biological_process											owl:Class	
GO:0030201	biolink:NamedThing	heparan sulfate proteoglycan metabolic process	The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.	got7fsn_ti	heparin proteoglycan metabolic process|heparan sulphate proteoglycan metabolic process|heparan sulphate proteoglycan metabolism|heparan sulfate proteoglycan metabolism													biological_process											owl:Class	
GO:0003299	biolink:NamedThing	muscle hypertrophy in response to stress	The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis.	got7fsn_ti							dph	2009-10-22T09:26:10Z						biological_process											owl:Class	
GO:0009891	biolink:NamedThing	positive regulation of biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.	got7fsn_ti	positive regulation of biosynthesis|positive regulation of anabolism|upregulation of biosynthetic process|up regulation of biosynthetic process|stimulation of biosynthetic process|activation of biosynthetic process|positive regulation of synthesis|positive regulation of formation|up-regulation of biosynthetic process													biological_process											owl:Class	
GO:0002171	biolink:NamedThing	low-affinity IgA receptor activity	Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	low affinity IgA receptor activity						hjd	2010-05-06T05:01:41Z						molecular_function											owl:Class	
GO:0048721	biolink:NamedThing	clypeus morphogenesis	The process in which the anatomical structures of the clypeus are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0009243	biolink:NamedThing	O antigen biosynthetic process	The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.	got7fsn_ti	O antigen formation|O antigen anabolism|O antigen biosynthesis|O antigen synthesis													biological_process											owl:Class	
GO:0071070	biolink:NamedThing	alpha4-beta1 integrin-thrombospondin-2 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2.	got7fsn_ti	ITGA4-ITGB1-THBS2 complex						mah	2009-11-03T04:05:56Z						cellular_component											owl:Class	
GO:0043894	biolink:NamedThing	acetyl-CoA synthetase acetyltransferase activity	Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate.	got7fsn_ti	Pat|protein acetyltransferase activity|Pat enzyme													molecular_function											owl:Class	
GO:0106050	biolink:NamedThing	tRNA 2'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.	got7fsn_ti							hjd	2017-08-11T20:30:31Z						molecular_function											owl:Class	
GO:0047565	biolink:NamedThing	3-hydroxypropionate dehydrogenase (NAD+) activity	Catalysis of the reaction: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + H(+) + NADH.	got7fsn_ti	3-hydroxypropanoate:NAD+ oxidoreductase activity											KEGG_REACTION:R01608|EC:1.1.1.59|RHEA:13357|MetaCyc:3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0050450	biolink:NamedThing	citrate (Re)-synthase activity	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group.	got7fsn_ti	citrate oxaloacetate-lyase ((pro-3R)-CH(2)COO(-)->acetyl-CoA) activity|acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-R)-carboxymethyl-forming]|(R)-citrate synthase activity|Re-citrate-synthase activity|citrate oxaloacetate-lyase [(pro-3R)-CH2COO-rightacetyl-CoA]											EC:2.3.3.3|MetaCyc:CITRATE-RE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0036440	biolink:NamedThing	citrate synthase activity	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.	got7fsn_ti							bf	2013-09-30T16:21:50Z				KEGG_REACTION:R00351|RHEA:16845		molecular_function											owl:Class	
GO:1990737	biolink:NamedThing	response to manganese-induced endoplasmic reticulum stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus.	got7fsn_ti	response to Mn-induced ER stress|response to manganese-induced ER stress|manganese-induced ER stress response						bf	2015-04-30T13:48:45Z						biological_process											owl:Class	
GO:0034976	biolink:NamedThing	response to endoplasmic reticulum stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.	got7fsn_ti	cellular response to endoplasmic reticulum stress|ER stress response|response to ER stress													biological_process											owl:Class	
GO:0019679	biolink:NamedThing	propionate metabolic process, methylcitrate cycle	The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.	got7fsn_ti	propionate metabolism, methylcitrate cycle											MetaCyc:PWY0-42		biological_process											owl:Class	
GO:0019541	biolink:NamedThing	propionate metabolic process	The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants.	got7fsn_ti	propanoate metabolism|propanoate metabolic process|propionate metabolism													biological_process											owl:Class	
GO:0032280	biolink:NamedThing	symmetric synapse	A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typcially inhibitory.	got7fsn_ti	Gray's type II synapse				The term 'symmetric' in this name refers only to gross morphology.  There is no implication of functional symmetry.									cellular_component											owl:Class	
GO:0098984	biolink:NamedThing	neuron to neuron synapse	A synapse in which pre and post-synaptic cells are neurons.	got7fsn_ti														cellular_component											owl:Class	
GO:0050093	biolink:NamedThing	methanol dehydrogenase activity	Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH.	got7fsn_ti	methanol:NAD+ oxidoreductase activity											RHEA:19401|EC:1.1.1.244|MetaCyc:METHANOL-DEHYDROGENASE-RXN|KEGG_REACTION:R00605		molecular_function											owl:Class	
GO:0015813	biolink:NamedThing	L-glutamate transmembrane transport	The directed movement of L-glutamate across a membrane.	got7fsn_ti	mitochondrial aspartate/glutamate transport|L-glutamate transport										GO:0089711			biological_process											owl:Class	
GO:0050309	biolink:NamedThing	sugar-terminal-phosphatase activity	Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate.	got7fsn_ti	sugar-omega-phosphate phosphohydrolase activity|xylitol-5-phosphatase activity											EC:3.1.3.58		molecular_function											owl:Class	
GO:0061080	biolink:NamedThing	right horn of sinus venosus development	The progression of the right horn of the sinus venosus from its formation to the mature structure.	got7fsn_ti							dph	2010-04-08T02:45:10Z						biological_process											owl:Class	
GO:0007162	biolink:NamedThing	negative regulation of cell adhesion	Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.	got7fsn_ti	down-regulation of cell adhesion|downregulation of cell adhesion|cell adhesion receptor inhibitor activity|down regulation of cell adhesion|inhibition of cell adhesion													biological_process											owl:Class	
GO:0031626	biolink:NamedThing	beta-endorphin binding	Binding to beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.	got7fsn_ti														molecular_function											owl:Class	
GO:0032837	biolink:NamedThing	distributive segregation	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally.	got7fsn_ti														biological_process											owl:Class	
GO:0045132	biolink:NamedThing	meiotic chromosome segregation	The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0070042	biolink:NamedThing	rRNA (uridine-N3-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.	got7fsn_ti														molecular_function											owl:Class	
GO:0016436	biolink:NamedThing	rRNA (uridine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.	got7fsn_ti														molecular_function											owl:Class	
GO:0032310	biolink:NamedThing	prostaglandin secretion	The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.	got7fsn_ti	prostacyclin secretion													biological_process											owl:Class	
GO:0031053	biolink:NamedThing	primary miRNA processing	Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.	got7fsn_ti	primary microRNA processing|pri-miRNA processing													biological_process											owl:Class	
GO:0006194	biolink:NamedThing	dIDP phosphorylation	The process of introducing a phosphate group into dIDP, deoxyinosine diphosphate, to produce dITP.	got7fsn_ti														biological_process											owl:Class	
GO:0047252	biolink:NamedThing	beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity	Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate.	got7fsn_ti	beta-D-mannosylphosphodecaprenol:1,6-alpha-D-mannosyloligosaccharide 1,6-alpha-D-mannosyltransferase activity|mannosylphospholipid-methylmannoside alpha-1,6-mannosyltransferase activity											EC:2.4.1.199|MetaCyc:2.4.1.199-RXN		molecular_function											owl:Class	
GO:0000030	biolink:NamedThing	mannosyltransferase activity	Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	got7fsn_ti												Reactome:R-HSA-162797|Reactome:R-HSA-446198|Reactome:R-HSA-4720497|Reactome:R-HSA-162830		molecular_function											owl:Class	
GO:0140114	biolink:NamedThing	cellular detoxification of fluoride	Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14391					pg	2017-10-23T15:39:43Z						biological_process											owl:Class	
GO:0007378	biolink:NamedThing	amnioserosa formation	Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift.	got7fsn_ti														biological_process											owl:Class	
GO:0004556	biolink:NamedThing	alpha-amylase activity	Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.	got7fsn_ti	endoamylase activity|1,4-alpha-D-glucan glucanohydrolase activity|taka-amylase A|glycogenase activity|alpha amylase activity											MetaCyc:RXN-1825|Reactome:R-HSA-191114|Reactome:R-HSA-188979|EC:3.2.1.1|MetaCyc:ALPHA-AMYL-RXN|MetaCyc:RXN-1823		molecular_function											owl:Class	
GO:0045330	biolink:NamedThing	aspartyl esterase activity	Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue.	got7fsn_ti														molecular_function											owl:Class	
GO:0000350	biolink:NamedThing	generation of catalytic spliceosome for second transesterification step	Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.	got7fsn_ti	spliceosomal C2 complex biosynthesis|spliceosomal A2-3 complex formation|formation of spliceosomal C1 complex|formation of catalytic spliceosome for second transesterification step|spliceosomal A2-3 complex biosynthesis|lariat formation, 5'-splice site cleavage|formation of catalytic U12-type spliceosome for second transesterification step|catalytic spliceosome assembly for second transesterification step|spliceosomal C2 complex formation|formation of spliceosomal A2-2 complex|formation of catalytic U2-type spliceosome for second transesterification step				Note that this step represents formation of the A2-3 complex (yeast) or the C2 complex (mammalian).						GO:0000359|GO:0000358			biological_process											owl:Class	
GO:0002394	biolink:NamedThing	tolerance induction in gut-associated lymphoid tissue	Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).	got7fsn_ti	oral tolerance|tolerance induction in GALT													biological_process											owl:Class	
GO:0002401	biolink:NamedThing	tolerance induction in mucosal-associated lymphoid tissue	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT).	got7fsn_ti	tolerance induction in MALT													biological_process											owl:Class	
GO:0044542	biolink:NamedThing	plasminogen activation in other organism	The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism.	got7fsn_ti							jl	2012-03-22T11:40:03Z						biological_process											owl:Class	
GO:0044541	biolink:NamedThing	zymogen activation in other organism	The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism.	got7fsn_ti							jl	2012-03-22T11:39:41Z						biological_process											owl:Class	
GO:0043197	biolink:NamedThing	dendritic spine	A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse.  They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or  branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.	got7fsn_ti	sessile dendritic spine|dendrite spine|branched dendritic spine|stubby dendritic spine|mushroom dendritic spine|thin dendritic spine											Wikipedia:Dendritic_spine|NIF_Subcellular:sao1799103720		cellular_component											owl:Class	
GO:0098794	biolink:NamedThing	postsynapse	The part of a synapse that is part of the post-synaptic cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0031996	biolink:NamedThing	thioesterase binding	Binding to a thioesterase.	got7fsn_ti	thiolesterase binding													molecular_function											owl:Class	
GO:0070294	biolink:NamedThing	renal sodium ion absorption	A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	got7fsn_ti	nephron sodium ion absorption|renal sodium ion reabsorption													biological_process											owl:Class	
GO:0004048	biolink:NamedThing	anthranilate phosphoribosyltransferase activity	Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.	got7fsn_ti	anthranilate-PP-ribose-P phosphoribosyltransferase activity|N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase activity|PRT|phosphoribosylanthranilate transferase activity|phosphoribosyl-anthranilate diphosphorylase activity|phosphoribosylanthranilate pyrophosphorylase activity|anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase activity|phosphoribosyl-anthranilate pyrophosphorylase activity|anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase activity											RHEA:11768|MetaCyc:PRTRANS-RXN|EC:2.4.2.18|KEGG_REACTION:R01073		molecular_function											owl:Class	
GO:0050315	biolink:NamedThing	synephrine dehydratase activity	Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium.	got7fsn_ti	1-(4-hydroxyphenyl)-2-(methylamino)ethanol hydro-lyase (methylamine-forming)											EC:4.2.1.88|RHEA:32203|KEGG_REACTION:R03359|MetaCyc:SYNEPHRINE-DEHYDRATASE-RXN		molecular_function											owl:Class	
GO:0015481	biolink:NamedThing	maltose transporting porin activity	Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	got7fsn_ti	maltoporin											Wikipedia:Maltoporin		molecular_function											owl:Class	
GO:0046916	biolink:NamedThing	cellular transition metal ion homeostasis	Any process involved in the maintenance of an internal steady state of transition metal ions at the level of a cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	got7fsn_ti														biological_process											owl:Class	
GO:0033605	biolink:NamedThing	positive regulation of catecholamine secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.	got7fsn_ti	up regulation of catecholamine secretion|activation of catecholamine secretion|upregulation of catecholamine secretion|stimulation of catecholamine secretion|up-regulation of catecholamine secretion													biological_process											owl:Class	
GO:0009714	biolink:NamedThing	chalcone metabolic process	The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives.	got7fsn_ti	chalcone metabolism													biological_process											owl:Class	
GO:0009698	biolink:NamedThing	phenylpropanoid metabolic process	The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.	got7fsn_ti	phenylpropanoid metabolism											MetaCyc:PWY1F-467		biological_process											owl:Class	
GO:0033330	biolink:NamedThing	kaempferol O-glucoside biosynthetic process	The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol.	got7fsn_ti	kaempferol O-glucoside synthesit|kaempferol O-glucoside anabolism|kaempferol O-glucoside biosynthesis|kaempferol O-glucoside formation											MetaCyc:PWY-5320		biological_process											owl:Class	
GO:0033329	biolink:NamedThing	kaempferol O-glucoside metabolic process	The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol.	got7fsn_ti	kaempferol O-glucoside metabolism													biological_process											owl:Class	
GO:0103023	biolink:NamedThing	ITPase activity	Catalysis of the reaction: ITP + H2O <=> H+ + IDP + hydrogenphosphate.	got7fsn_ti												MetaCyc:RXN0-5073|RHEA:28330		molecular_function											owl:Class	
GO:0097004	biolink:NamedThing	adipokinetic hormone binding	Binding to an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.	got7fsn_ti	AKH binding						pr	2011-03-14T12:50:02Z						molecular_function											owl:Class	
GO:0004081	biolink:NamedThing	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity	Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.	got7fsn_ti	Ap4Aase activity|bis(5'-guanosyl)-tetraphosphatase activity|Ap4A hydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase|diadenosine P1,P4-tetraphosphatase activity|bis(5'-adenosyl)-tetraphosphatase activity|Ap(4)A hydrolase activity|dinucleosidetetraphosphatase (asymmetrical) activity|diguanosinetetraphosphatase (asymmetrical) activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity|diadenosinetetraphosphatase (asymmetrical) activity|Ap(4)Aase activity|dinucleoside tetraphosphatase activity|diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity|P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity|1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity											EC:3.6.1.17|MetaCyc:3.6.1.17-RXN|Reactome:R-HSA-5696197|RHEA:22484		molecular_function											owl:Class	
GO:0008796	biolink:NamedThing	bis(5'-nucleosyl)-tetraphosphatase activity	Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.	got7fsn_ti														molecular_function											owl:Class	
GO:0030374	biolink:NamedThing	nuclear receptor coactivator activity	A transcription coactivator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.	got7fsn_ti	ligand-dependent nuclear receptor transcription coactivator activity|transcription factor activity, ligand-activated RNA polymerase II transcription factor binding|ligand-dependent nuclear receptor transcription co-activator activity|ligand-activated RNA polymerase II transcription factor binding transcription factor activity|nuclear receptor transcription coactivator activity	https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/20464			For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.		bf	2011-11-29T01:53:30Z			GO:0038049			molecular_function											owl:Class	
GO:0003713	biolink:NamedThing	transcription coactivator activity	A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.	got7fsn_ti	transcription co-activator activity|RNA polymerase II transcription co-activator activity|RNA polymerase II transcription coactivator activity|RNA polymerase II transcription mediator activity|transcription coactivator activity	https://github.com/geneontology/go-ontology/issues/15998|https://github.com/geneontology/go-ontology/issues/20464|https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/15665			For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.		krc	2010-11-24T03:08:19Z			GO:0001105			molecular_function											owl:Class	
GO:0106018	biolink:NamedThing	phosphatidylinositol-3,5-bisphosphate phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.	got7fsn_ti							hjd	2017-05-10T14:19:13Z						molecular_function											owl:Class	
GO:0005080	biolink:NamedThing	protein kinase C binding	Binding to protein kinase C.	got7fsn_ti	PKC alpha binding|protein kinase C delta binding|PKC eta binding|PKC binding|protein kinase C eta binding|PKC delta binding|protein kinase C alpha binding										GO:0072568|GO:0072569|GO:0097024			molecular_function											owl:Class	
GO:0034447	biolink:NamedThing	very-low-density lipoprotein particle clearance	The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti	VLDL clearance													biological_process											owl:Class	
GO:0047611	biolink:NamedThing	acetylspermidine deacetylase activity	Catalysis of the reaction: N(8)-acetylspermidine + H(2)O = acetate + spermidine.	got7fsn_ti	N(1)-acetylspermidine amidohydrolase activity|N8-acetylspermidine deacetylase activity|N-acetylspermidine deacetylase activity|8-N-acetylspermidine amidohydrolase activity|N(8)-monoacetylspermidine deacetylase activity|N8-acetylspermidine amidohydrolase activity|N(8)-acetylspermidine deacetylase activity|N(8)-acetylspermidine amidohydrolase activity|N8-monoacetylspermidine deacetylase activity|N1-acetylspermidine amidohydrolase activity											KEGG_REACTION:R07300|RHEA:23928|EC:3.5.1.48|MetaCyc:ACETYLSPERMIDINE-DEACETYLASE-RXN		molecular_function											owl:Class	
GO:0047295	biolink:NamedThing	geranylgeranylglycerol-phosphate geranylgeranyltransferase activity	Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.	got7fsn_ti	geranylgeranyltransferase II|geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity|geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity											EC:2.5.1.42|MetaCyc:2.5.1.42-RXN|KEGG_REACTION:R04520|RHEA:18109		molecular_function											owl:Class	
GO:0051444	biolink:NamedThing	negative regulation of ubiquitin-protein transferase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.	got7fsn_ti	ubiquitin transferase inhibitor|anaphase-promoting complex inhibition|anaphase promoting complex inhibition|anaphase-promoting complex inhibitor|negative regulation of ubiquitin transferase activity|anaphase promoting complex inhibitor|APC inhibitor|SCF complex inhibitor|inhibition of ubiquitin transferase activity|down-regulation of ubiquitin transferase activity|down regulation of ubiquitin transferase activity|APC inhibition|downregulation of ubiquitin transferase activity													biological_process											owl:Class	
GO:0031397	biolink:NamedThing	negative regulation of protein ubiquitination	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.	got7fsn_ti	down regulation of protein ubiquitination|down-regulation of protein ubiquitination|inhibition of protein ubiquitination|downregulation of protein ubiquitination													biological_process											owl:Class	
GO:0090162	biolink:NamedThing	establishment of epithelial cell polarity	The specification and formation of anisotropic intracellular organization of an epithelial cell.	got7fsn_ti							tb	2009-12-08T08:58:27Z						biological_process											owl:Class	
GO:1905330	biolink:NamedThing	regulation of morphogenesis of an epithelium	Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium.	got7fsn_ti	regulation of epithelium morphogenesis				An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-07-22T07:13:49Z						biological_process											owl:Class	
GO:0005140	biolink:NamedThing	interleukin-9 receptor binding	Binding to an interleukin-9 receptor.	got7fsn_ti	interleukin-9 receptor ligand|IL-9													molecular_function											owl:Class	
GO:0032359	biolink:NamedThing	provirus excision	The molecular events that lead to the excision of a viral genome from the host genome.	got7fsn_ti	prophage excision													biological_process											owl:Class	
GO:0060218	biolink:NamedThing	hematopoietic stem cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.	got7fsn_ti	haematopoietic stem cell differentiation|haemopoietic stem cell differentiation|hemopoietic stem cell differentiation													biological_process											owl:Class	
GO:0042284	biolink:NamedThing	sphingolipid delta-4 desaturase activity	Catalysis of the reaction: a dihydroceramide + 2 ferrocytochrome b5 + O2 + 2 H+ -> a sphingosine ceramide (aka (4E)-sphing-4-enine ceramide) + 2 ferricytochrome b5 + 2 H2O.	got7fsn_ti	delta-4 sphingolipid desaturase activity	https://github.com/geneontology/go-ontology/issues/21105										RHEA:46544|EC:1.14.19.17|Reactome:R-HSA-428259		molecular_function											owl:Class	
GO:0047704	biolink:NamedThing	bile-salt sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.	got7fsn_ti	3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase activity|bile-salt sulphotransferase activity|bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity|glycolithocholate sulfotransferase activity|bile acid sulfotransferase I activity|bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase activity|BAST I activity											RHEA:14013|EC:2.8.2.14|MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0042351	biolink:NamedThing	'de novo' GDP-L-fucose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).	got7fsn_ti	'de novo' GDP-L-fucose synthesis|'de novo' GDP-L-fucose biosynthesis|'de novo' GDP-L-fucose anabolism|GDP-L-fucose biosynthetic process, de novo pathway|GDP-L-fucose biosynthesis, de novo pathway|'de novo' GDP-L-fucose formation											MetaCyc:PWY-66		biological_process											owl:Class	
GO:0042350	biolink:NamedThing	GDP-L-fucose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-L-fucose formation|GDP-L-fucose synthesis|GDP-L-fucose anabolism|GDP-L-fucose biosynthesis													biological_process											owl:Class	
GO:0035448	biolink:NamedThing	extrinsic component of thylakoid membrane	The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	peripheral to thylakoid membrane|extrinsic to thylakoid membrane						bf	2010-04-16T10:11:32Z						cellular_component											owl:Class	
GO:0019898	biolink:NamedThing	extrinsic component of membrane	The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	peripheral membrane protein|extrinsic to membrane				Note that proteins extrinsic to membranes can be removed by treatments that do not disrupt the membrane, such as salt solutions.						GO:0030396	Wikipedia:Peripheral_membrane_protein		cellular_component											owl:Class	
GO:0016606	biolink:NamedThing	LYSP100-associated nuclear domain	A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies.	got7fsn_ti	LANDs													cellular_component											owl:Class	
GO:0060427	biolink:NamedThing	lung connective tissue development	The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.	got7fsn_ti	pulmonary connective tissue development													biological_process											owl:Class	
GO:0043117	biolink:NamedThing	positive regulation of vascular permeability	Any process that increases the extent to which blood vessels can be pervaded by fluid.	got7fsn_ti	activation of vascular permeability|stimulation of vascular permeability|up-regulation of vascular permeability|up regulation of vascular permeability|upregulation of vascular permeability													biological_process											owl:Class	
GO:0051993	biolink:NamedThing	abscisic acid glucose ester beta-glucosidase activity	Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose.	got7fsn_ti	ABA-GE beta-glucosidase activity						ai	2010-07-16T02:16:59Z				MetaCyc:RXN-11469|EC:3.2.1.175|RHEA:31347		molecular_function											owl:Class	
GO:0038041	biolink:NamedThing	cross-receptor inhibition within G protein-coupled receptor heterodimer	Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.	got7fsn_ti	cross-receptor inhibition within G-protein coupled receptor heterodimer						bf	2011-11-02T04:52:24Z						biological_process											owl:Class	
GO:2000272	biolink:NamedThing	negative regulation of signaling receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.	got7fsn_ti	negative regulation of receptor activity|negative regulation of signalling receptor activity						bf	2010-12-02T09:28:47Z						biological_process											owl:Class	
GO:0005963	biolink:NamedThing	magnesium-dependent protein serine/threonine phosphatase complex	An enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase.	got7fsn_ti														cellular_component											owl:Class	
GO:0008474	biolink:NamedThing	palmitoyl-(protein) hydrolase activity	Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein.	got7fsn_ti	palmitoyl-[protein] hydrolase|palmitoyl-protein thiolesterase activity|palmitoyl-protein hydrolase activity|palmitoyl-protein thioesterase activity											Reactome:R-HSA-8933328|Reactome:R-HSA-203613|EC:3.1.2.22|Reactome:R-HSA-9647994|Reactome:R-HSA-5690517|RHEA:19233|MetaCyc:3.1.2.22-RXN		molecular_function											owl:Class	
GO:0098599	biolink:NamedThing	palmitoyl hydrolase activity	Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.	got7fsn_ti							dos	2014-04-11T17:57:36Z				Reactome:R-HSA-9027670|Reactome:R-HSA-5690046		molecular_function											owl:Class	
GO:0008989	biolink:NamedThing	rRNA (guanine-N1-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine.	got7fsn_ti	S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase activity|ribosomal ribonucleate guanine 1-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity											MetaCyc:RRNA-GUANINE-N1--METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0018741	biolink:NamedThing	alkyl sulfatase activity	Catalysis of the reaction: dodecyl sulfate + H2O = sulfate + H+ + 1-dodecanol.	got7fsn_ti	alkyl sulphatase activity											UM-BBD_reactionID:r0602|EC:3.1.6.-		molecular_function											owl:Class	
GO:0043470	biolink:NamedThing	regulation of carbohydrate catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.	got7fsn_ti														biological_process											owl:Class	
GO:0009894	biolink:NamedThing	regulation of catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.	got7fsn_ti	regulation of degradation|regulation of breakdown|regulation of catabolism													biological_process											owl:Class	
GO:0044158	biolink:NamedThing	host cell wall	The rigid or semi-rigid envelope lying outside the host cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.	got7fsn_ti							jl	2009-08-11T04:09:23Z						cellular_component											owl:Class	
GO:0010049	biolink:NamedThing	acquisition of plant reproductive competence	The process in which a plant acquires the ability to respond to a floral inductive signal.	got7fsn_ti	acquisition of reproductive competence													biological_process											owl:Class	
GO:0043013	biolink:NamedThing	negative regulation of fusion of sperm to egg plasma membrane	Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.	got7fsn_ti	inhibition of fusion of sperm to egg plasma membrane|negative regulation of sperm-oocyte fusion|downregulation of fusion of sperm to egg plasma membrane|inhibition of sperm-oocyte fusion|down regulation of fusion of sperm to egg plasma membrane|down-regulation of fusion of sperm to egg plasma membrane													biological_process											owl:Class	
GO:0047301	biolink:NamedThing	valine-3-methyl-2-oxovalerate transaminase activity	Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.	got7fsn_ti	valine--3-methyl-2-oxovalerate aminotransferase activity|valine-2-keto-methylvalerate aminotransferase activity|valine-3-methyl-2-oxovalerate aminotransferase activity|valine--isoleucine aminotransferase activity|valine--isoleucine transaminase activity|L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase activity											RHEA:11468|MetaCyc:2.6.1.32-RXN|EC:2.6.1.32|KEGG_REACTION:R02200		molecular_function											owl:Class	
GO:1990356	biolink:NamedThing	sumoylated E2 ligase complex	A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase.	got7fsn_ti					An example of this is UBC9 in human (UniProt symbol P63279) in PMID:18691969 (inferred from direct assay).		bhm	2014-04-02T14:06:56Z						cellular_component											owl:Class	
GO:0050091	biolink:NamedThing	melilotate 3-monooxygenase activity	Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+).	got7fsn_ti	melilotic hydroxylase activity|2-hydroxyphenylpropionic hydroxylase activity|2-hydroxyphenylpropionate hydroxylase activity|melilotate hydroxylase activity|3-(2-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (3-hydroxylating)											EC:1.14.13.4|KEGG_REACTION:R03369|MetaCyc:MELILOTATE-3-MONOOXYGENASE-RXN|RHEA:17669		molecular_function											owl:Class	
GO:0050082	biolink:NamedThing	maltose phosphorylase activity	Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.	got7fsn_ti	maltose:phosphate 1-beta-D-glucosyltransferase activity											MetaCyc:MALTOSE-PHOSPHORYLASE-RXN|RHEA:21116|EC:2.4.1.8		molecular_function											owl:Class	
GO:0016263	biolink:NamedThing	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan.	got7fsn_ti	Core 1 GalT|UDPgalactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity|UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity|uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase activity											RHEA:15621|Reactome:R-HSA-6785524|EC:2.4.1.122|Reactome:R-HSA-1964505|MetaCyc:2.4.1.122-RXN		molecular_function											owl:Class	
GO:0008403	biolink:NamedThing	25-hydroxycholecalciferol-24-hydroxylase activity	Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.	got7fsn_ti	cytochrome P450 CYP24|25-hydroxyvitamin D3 24-hydroxylase activity										GO:0030344			molecular_function											owl:Class	
GO:0032390	biolink:NamedThing	MutLbeta complex	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.	got7fsn_ti	MLH1/PMS1 complex|MMR complex													cellular_component											owl:Class	
GO:0110070	biolink:NamedThing	cellularization cleavage furrow	A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14543|https://github.com/geneontology/go-ontology/issues/21737					kmv	2017-11-22T20:10:14Z						cellular_component											owl:Class	
GO:0098590	biolink:NamedThing	plasma membrane region	A membrane that is a (regional) part of the plasma membrane.	got7fsn_ti	region of plasma membrane				Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.		dos	2014-03-06T11:55:32Z						cellular_component											owl:Class	
GO:0042093	biolink:NamedThing	T-helper cell differentiation	The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.	got7fsn_ti	T-helper cell development|helper T cell differentiation													biological_process											owl:Class	
GO:0002294	biolink:NamedThing	CD4-positive, alpha-beta T cell differentiation involved in immune response	The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	got7fsn_ti	CD4-positive, alpha-beta T cell differentiation during immune response|CD4-positive, alpha-beta T-cell differentiation during immune response|CD4-positive, alpha-beta T-lymphocyte differentiation during immune response|CD4-positive, alpha-beta T lymphocyte differentiation during immune response|CD4-positive, alpha-beta T cell development involved in immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0070317	biolink:NamedThing	negative regulation of G0 to G1 transition	A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.	got7fsn_ti	maintenance of G0 phase|maintenance of cell cycle quiescence|maintenance of cell quiescence|maintenance of G0 arrest													biological_process											owl:Class	
GO:0032983	biolink:NamedThing	kainate selective glutamate receptor complex	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits.	got7fsn_ti														cellular_component											owl:Class	
GO:0004080	biolink:NamedThing	biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming)).	got7fsn_ti	propionyl coenzyme A holocarboxylase synthetase activity|biotin-propionyl coenzyme A carboxylase synthetase activity|holocarboxylase synthetase activity|biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) synthetase activity|biotin:apo-propanoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|propionyl-CoA holocarboxylase synthetase activity|biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) ligase activity|biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] synthetase activity											MetaCyc:6.3.4.10-RXN|RHEA:11204|EC:6.3.4.10		molecular_function											owl:Class	
GO:0031639	biolink:NamedThing	plasminogen activation	The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.	got7fsn_ti	cleavage of plasminogen to plasmin													biological_process											owl:Class	
GO:0015043	biolink:NamedThing	leghemoglobin reductase activity	Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin.	got7fsn_ti	ferric leghemoglobin reductase activity|NAD(P)H:ferrileghemoglobin oxidoreductase activity											MetaCyc:LEGHEMOGLOBIN-REDUCTASE-RXN|EC:1.6.2.6		molecular_function											owl:Class	
GO:0016653	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein.	got7fsn_ti	oxidoreductase activity, acting on NADH or NADPH, haem protein as acceptor|oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor											EC:1.6.2.-		molecular_function											owl:Class	
GO:0031074	biolink:NamedThing	nucleocytoplasmic transport complex	Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores.	got7fsn_ti	nucleocytoplasmic shuttling complex													cellular_component											owl:Class	
GO:0042100	biolink:NamedThing	B cell proliferation	The expansion of a B cell population by cell division. Follows B cell activation.	got7fsn_ti	B-lymphocyte proliferation|B-cell proliferation|B lymphocyte proliferation										GO:0042114			biological_process											owl:Class	
GO:0097480	biolink:NamedThing	establishment of synaptic vesicle localization	The directed movement of a synaptic vesicle or vesicles to a specific location.	got7fsn_ti	establishment of synaptic vesicle localisation						pr	2013-05-22T14:32:12Z						biological_process											owl:Class	
GO:0005903	biolink:NamedThing	brush border	The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.	got7fsn_ti												Wikipedia:Brush_border		cellular_component											owl:Class	
GO:0048275	biolink:NamedThing	N-terminal peptidyl-arginine acetylation	The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase.	got7fsn_ti												RESID:AA0354		biological_process											owl:Class	
GO:0040004	biolink:NamedThing	collagen and cuticulin-based cuticle attachment to epithelium	Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans.	got7fsn_ti	cuticular attachment to epithelium													biological_process											owl:Class	
GO:0102640	biolink:NamedThing	paspalinine synthase activity	Catalysis of the reaction: paspalicine + O2 + NADPH + H+ <=> paspalinine + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15738		molecular_function											owl:Class	
GO:0033314	biolink:NamedThing	mitotic DNA replication checkpoint signaling	A signal transduction process that contributes to a mitotic DNA replication checkpoint.	got7fsn_ti	S-M checkpoint|mitotic DNA replication checkpoint|signal transduction involved in mitotic G2/M transition decatenation checkpoint|S-phase checkpoint|mitotic cell cycle DNA replication checkpoint|signal transduction involved in mitotic DNA replication checkpoint|signal transduction involved in S-M checkpoint|S-M DNA replication checkpoint										GO:0072459|GO:0072446|GO:0031574|GO:0072443			biological_process											owl:Class	
GO:0000076	biolink:NamedThing	DNA replication checkpoint signaling	A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.	got7fsn_ti	signal transduction involved in DNA replication checkpoint|DNA replication checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072437			biological_process											owl:Class	
GO:0050145	biolink:NamedThing	nucleoside monophosphate kinase activity	Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate.	got7fsn_ti	nucleotide kinase activity|nucleoside-phosphate kinase activity|ATP:nucleoside-phosphate phosphotransferase activity|nucleoside monophosphate kinase activity|NMP-kinase activity										GO:0019201	Reactome:R-HSA-73548|Reactome:R-HSA-73635|Reactome:R-HSA-6788798|EC:2.7.4.4|Reactome:R-HSA-75125|MetaCyc:NUCLEOSIDE-PHOSPHATE-KINASE-RXN|Reactome:R-HSA-75126|Reactome:R-HSA-2162092|Reactome:R-HSA-6788810|RHEA:24036		molecular_function											owl:Class	
GO:0052023	biolink:NamedThing	modulation by symbiont of salicylic acid levels in host	The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of salicylic acid levels in other organism involved in symbiotic interaction										GO:0052469			biological_process											owl:Class	
GO:0052019	biolink:NamedThing	modulation by symbiont of host hormone or growth regulator levels	The alteration by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction										GO:0052186			biological_process											owl:Class	
GO:0061806	biolink:NamedThing	regulation of DNA recombination at centromere	Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA.	got7fsn_ti	regulation of centromeric recombination						dph	2016-11-10T15:17:11Z						biological_process											owl:Class	
GO:0000018	biolink:NamedThing	regulation of DNA recombination	Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.	got7fsn_ti														biological_process											owl:Class	
GO:0015471	biolink:NamedThing	nucleoside-specific channel forming porin activity	Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	got7fsn_ti														molecular_function											owl:Class	
GO:0060121	biolink:NamedThing	vestibular receptor cell stereocilium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells.	got7fsn_ti	vestibular hair cell stereocilium organization|vestibular receptor cell stereocilium organization and biogenesis|vestibular receptor cell stereocilium organisation													biological_process											owl:Class	
GO:0050616	biolink:NamedThing	secologanin synthase activity	Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O.	got7fsn_ti	loganin:oxygen oxidoreductase (ring-cleaving)											EC:1.14.19.62|RHEA:20585|MetaCyc:1.3.3.9-RXN		molecular_function											owl:Class	
GO:0047451	biolink:NamedThing	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein].	got7fsn_ti	3-hydroxyoctanoyl-acyl-carrier-protein dehydratase activity|3-hydroxyoctanoyl-ACP dehydratase activity|D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase activity|(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase activity|3-hydroxyoctanoyl-[acyl-carrier protein] dehydratase activity|D-3-hydroxyoctanoyl-acyl carrier protein dehydratase activity|beta-hydroxyoctanoyl-acyl carrier protein dehydrase activity|beta-hydroxyoctanoyl-ACP-dehydrase activity|beta-hydroxyoctanoyl thioester dehydratase activity|(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase activity|(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase (oct-2-enoyl-acyl-carrier protein-forming)											RHEA:41844|MetaCyc:4.2.1.59-RXN|EC:4.2.1.59|KEGG_REACTION:R04537		molecular_function											owl:Class	
GO:1903793	biolink:NamedThing	positive regulation of anion transport	Any process that activates or increases the frequency, rate or extent of anion transport.	got7fsn_ti	up regulation of anion transport|upregulation of anion transport|activation of anion transport|up-regulation of anion transport						sl	2015-01-12T21:50:30Z						biological_process											owl:Class	
GO:0043270	biolink:NamedThing	positive regulation of ion transport	Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	stimulation of ion transport|upregulation of ion transport|up regulation of ion transport|activation of ion transport|up-regulation of ion transport													biological_process											owl:Class	
GO:0004602	biolink:NamedThing	glutathione peroxidase activity	Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.	got7fsn_ti	GSH peroxidase activity|glutathione:hydrogen-peroxide oxidoreductase activity|reduced glutathione peroxidase activity|non-selenium glutathione peroxidase activity|selenium-glutathione peroxidase activity										GO:0016224	Reactome:R-HSA-3341277|Reactome:R-HSA-2161959|Reactome:R-HSA-3343700|Reactome:R-HSA-2161946|Reactome:R-HSA-6799695|Reactome:R-HSA-3341397|Reactome:R-HSA-2161999|Reactome:R-HSA-3323013|MetaCyc:GLUTATHIONE-PEROXIDASE-RXN|EC:1.11.1.9|RHEA:16833|Reactome:R-HSA-2161791|Reactome:R-HSA-71676		molecular_function											owl:Class	
GO:0002204	biolink:NamedThing	somatic recombination of immunoglobulin genes involved in immune response	The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response.	got7fsn_ti	somatic recombination of immunoglobulin genes during immune response|somatic recombination of antibody genes during immune response													biological_process											owl:Class	
GO:0032177	biolink:NamedThing	cellular bud neck split septin rings	Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.	got7fsn_ti														cellular_component											owl:Class	
GO:0071360	biolink:NamedThing	cellular response to exogenous dsRNA	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.	got7fsn_ti	cellular response to exogenous double-stranded RNA|cellular response to viral dsRNA						mah	2009-12-11T03:02:00Z						biological_process											owl:Class	
GO:0008120	biolink:NamedThing	ceramide glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.	got7fsn_ti	glucosylceramide synthase activity|uridine diphosphoglucose-ceramide glucosyltransferase activity|ceramide:UDP-glucose glucosyltransferase activity|UDP-glucose:N-acylsphingosine D-glucosyltransferase activity|UDP-glucose-ceramide glucosyltransferase activity|UDP-glucose:ceramide glucosyltransferase activity|ceramide:UDPGlc glucosyltransferase activity|UDPglucose:N-acylsphingosine D-glucosyltransferase activity											MetaCyc:CERAMIDE-GLUCOSYLTRANSFERASE-RXN|RHEA:12088|Reactome:R-HSA-1638104|EC:2.4.1.80		molecular_function											owl:Class	
GO:0035470	biolink:NamedThing	positive regulation of vascular wound healing	Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.	got7fsn_ti							bf	2010-04-22T10:49:09Z						biological_process											owl:Class	
GO:0090303	biolink:NamedThing	positive regulation of wound healing	Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.	got7fsn_ti							tb	2010-03-22T02:12:03Z						biological_process											owl:Class	
GO:0051619	biolink:NamedThing	inhibition of histamine uptake	Any process that prevents the activation of the directed movement of histamine into a cell.	got7fsn_ti	inhibition of histamine import													biological_process											owl:Class	
GO:0018290	biolink:NamedThing	iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide	The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.	got7fsn_ti	iron and molybdenum incorporation into iron-molybdenum-sulphur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulphide											RESID:AA0141		biological_process											owl:Class	
GO:0018291	biolink:NamedThing	molybdenum incorporation into iron-sulfur cluster	The incorporation of molybdenum into an iron-sulfur cluster.	got7fsn_ti	molybdenum incorporation into iron-sulphur cluster													biological_process											owl:Class	
GO:0017162	biolink:NamedThing	aryl hydrocarbon receptor binding	Binding to an aryl hydrocarbon receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0000346	biolink:NamedThing	transcription export complex	The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans.	got7fsn_ti	TREX complex													cellular_component											owl:Class	
GO:0061730	biolink:NamedThing	C-rich strand telomeric DNA binding	Binding to C-rich, single-stranded, telomere-associated DNA.	got7fsn_ti							dph	2015-08-20T09:08:27Z						molecular_function											owl:Class	
GO:0051816	biolink:NamedThing	acquisition of nutrients from other organism during symbiotic interaction	The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0045456	biolink:NamedThing	ecdysteroid biosynthetic process	The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.	got7fsn_ti	ecdysteroid formation|ecdysteroid anabolism|ecdysteroid synthesis|ecdysteroid biosynthesis													biological_process											owl:Class	
GO:0090021	biolink:NamedThing	positive regulation of posterior neural plate formation by Wnt signaling pathway	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and increasing the rate or extent of posterior neural plate formation.	got7fsn_ti	positive regulation of posterior neural plate formation by Wnt receptor signalling pathway|positive regulation of posterior neural plate formation by Wnt receptor signaling pathway|positive regulation of posterior neural plate formation by Wnt-activated signaling pathway						tb	2009-07-29T11:44:13Z						biological_process											owl:Class	
GO:0090058	biolink:NamedThing	metaxylem development	The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.	got7fsn_ti							tb	2009-08-11T03:05:15Z						biological_process											owl:Class	
GO:0051655	biolink:NamedThing	maintenance of vesicle location	Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of vesicle localization													biological_process											owl:Class	
GO:0016642	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group.	got7fsn_ti	oxidoreductase activity, acting on the CH-NH2 group of donors, disulphide as acceptor											EC:1.4.4.-		molecular_function											owl:Class	
GO:0034872	biolink:NamedThing	trans-geranyl-CoA isomerase activity	Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r1310|EC:5.2.1.-		molecular_function											owl:Class	
GO:0046269	biolink:NamedThing	toluene-4-sulfonate catabolic process	The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule.	got7fsn_ti	toluene-4-sulfonate catabolism|toluene-4-sulfonate breakdown|toluene-4-sulphonate catabolism|4-toluenesulfonate catabolism|4-toluenesulfonate catabolic process|toluene-4-sulfonate degradation|toluene-4-sulphonate catabolic process													biological_process											owl:Class	
GO:0032201	biolink:NamedThing	telomere maintenance via semi-conservative replication	The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication.	got7fsn_ti	equal telomere replication|telomeric replication fork progression|telomeric fork progression													biological_process											owl:Class	
GO:0000723	biolink:NamedThing	telomere maintenance	Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.	got7fsn_ti	regulation of telomere length													biological_process											owl:Class	
GO:0060575	biolink:NamedThing	intestinal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.	got7fsn_ti							dph	2009-05-06T08:17:56Z						biological_process											owl:Class	
GO:1903776	biolink:NamedThing	regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends	Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends.	got7fsn_ti							al	2015-01-06T17:08:24Z						biological_process											owl:Class	
GO:0051052	biolink:NamedThing	regulation of DNA metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.	got7fsn_ti	regulation of DNA metabolism													biological_process											owl:Class	
GO:0061260	biolink:NamedThing	mesonephric mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.	got7fsn_ti							dph	2010-08-30T02:25:08Z						biological_process											owl:Class	
GO:0072007	biolink:NamedThing	mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-01-25T01:59:09Z						biological_process											owl:Class	
GO:0042003	biolink:NamedThing	masculinization of hermaphrodite soma	Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans.	got7fsn_ti														biological_process											owl:Class	
GO:0042001	biolink:NamedThing	hermaphrodite somatic sex determination	The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.	got7fsn_ti											GO:0042002			biological_process											owl:Class	
GO:0071017	biolink:NamedThing	U12-type catalytic step 1 spliceosome	A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.	got7fsn_ti	minor catalytic step 1 spliceosome|mammalian U12-type spliceosomal complex B*|AT-AC catalytic step 1 spliceosome|yeast U12-type spliceosomal complex A1|U12-type activated spliceosome|mammalian U12-type spliceosomal complex B2						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0071012	biolink:NamedThing	catalytic step 1 spliceosome	A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.	got7fsn_ti	mammalian spliceosomal complex B2|activated spliceosome|mammalian spliceosomal complex B*|yeast spliceosomal complex A1						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0018072	biolink:NamedThing	peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid	The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit.	got7fsn_ti	peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine formation from peptidyl-glutamic acid|peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine anabolism from peptidyl-glutamic acid|peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine synthesis from peptidyl-glutamic acid											RESID:AA0170		biological_process											owl:Class	
GO:0042328	biolink:NamedThing	heparan sulfate N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate.	got7fsn_ti	heparan sulphate N-acetylglucosaminyltransferase activity|heparin N-acetylglucosaminyltransferase activity													molecular_function											owl:Class	
GO:0010144	biolink:NamedThing	pyridoxal phosphate biosynthetic process from pyridoxamine	The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine.	got7fsn_ti	vitamin B6 biosynthesis from pyridoxamine|pyridoxal 5'-phosphate salvage from pyridoxamine|pyridoxal phosphate anabolism from pyridoxamine|pyridoxal phosphate synthesis from pyridoxamine|vitamin B6 biosynthetic process from pyridoxamine|pyridoxal phosphate formation from pyridoxamine													biological_process											owl:Class	
GO:0009443	biolink:NamedThing	pyridoxal 5'-phosphate salvage	Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis.	got7fsn_ti	pyridoxal 5' phosphate salvage											MetaCyc:PLPSAL-PWY		biological_process											owl:Class	
GO:0000940	biolink:NamedThing	outer kinetochore	The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.	got7fsn_ti	condensed chromosome outer kinetochore|outer kinetochore of condensed chromosome|condensed nuclear chromosome outer kinetochore|outer kinetochore plate|outer kinetochore of condensed nuclear chromosome	https://github.com/geneontology/go-ontology/issues/21126									GO:0000942			cellular_component											owl:Class	
GO:0004618	biolink:NamedThing	phosphoglycerate kinase activity	Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H(+).	got7fsn_ti	phosphoglyceric acid kinase activity|glycerophosphate kinase activity|3-PGK|3-phosphoglyceric kinase activity|phosphoglyceric kinase activity|3-phosphoglycerate kinase activity|ATP:3-phospho-D-glycerate 1-phosphotransferase activity|phosphoglycerokinase activity|3-phosphoglyceric acid phosphokinase activity|3-phosphoglyceric acid kinase activity|ATP:D-3-phosphoglycerate 1-phosphotransferase activity|3-phosphoglycerate phosphokinase activity|ATP-3-phospho-D-glycerate-1-phosphotransferase activity|glycerate 3-phosphate kinase activity|PGK											KEGG_REACTION:R01512|MetaCyc:PHOSGLYPHOS-RXN|EC:2.7.2.3|RHEA:14801|Reactome:R-HSA-70486|Reactome:R-HSA-71850		molecular_function											owl:Class	
GO:0060496	biolink:NamedThing	mesenchymal-epithelial cell signaling involved in lung development	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.	got7fsn_ti	mesenchymal-epithelial cell signalling involved in lung development													biological_process											owl:Class	
GO:0022401	biolink:NamedThing	negative adaptation of signaling pathway	The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.	got7fsn_ti	negative adaptation of signal transduction pathway|negative adaptation of signalling pathway													biological_process											owl:Class	
GO:0015985	biolink:NamedThing	energy coupled proton transport, down electrochemical gradient	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP.	got7fsn_ti														biological_process											owl:Class	
GO:0070050	biolink:NamedThing	neuron cellular homeostasis	The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.	got7fsn_ti	neuron maintenance													biological_process											owl:Class	
GO:0051022	biolink:NamedThing	Rho GDP-dissociation inhibitor binding	Binding to a Rho GDP-dissociation inhibitor protein.	got7fsn_ti	Rho GDI binding													molecular_function											owl:Class	
GO:0051021	biolink:NamedThing	GDP-dissociation inhibitor binding	Binding to a GDP-dissociation inhibitor protein.	got7fsn_ti	GDI binding													molecular_function											owl:Class	
GO:0031900	biolink:NamedThing	chromoplast outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0009527	biolink:NamedThing	plastid outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0075606	biolink:NamedThing	transport of viral material towards nucleus	The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane.	got7fsn_ti	viral genome transport to host cell nucleus|transport of viral material to nucleus|cytoplasmic inwards viral transport				This process does not include the viral material crossing the nuclear membrane. For transport of viral material into the nucleus, consider instead: 'viral penetration into host nucleus ; GO:0075732'.		jl	2009-11-05T03:33:36Z				VZ:990		biological_process											owl:Class	
GO:0010920	biolink:NamedThing	negative regulation of inositol phosphate biosynthetic process	Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	got7fsn_ti	negative regulation of inositol phosphate biosynthesis													biological_process											owl:Class	
GO:0001873	biolink:NamedThing	polysaccharide immune receptor activity	Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	got7fsn_ti	polysaccharide receptor activity													molecular_function											owl:Class	
GO:0045745	biolink:NamedThing	positive regulation of G protein-coupled receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.	got7fsn_ti	positive regulation of G protein coupled receptor protein signaling pathway|positive regulation of G-protein-coupled receptor protein signalling pathway|positive regulation of G-protein-coupled receptor protein signaling pathway|upregulation of G-protein coupled receptor protein signaling pathway|up-regulation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein coupled receptor protein signaling pathway|positive regulation of GPCR protein signalling pathway|positive regulation of G protein coupled receptor protein signalling pathway|up regulation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein coupled receptor protein signalling pathway|activation of G-protein coupled receptor protein signaling pathway|stimulation of G-protein coupled receptor protein signaling pathway|positive regulation of GPCR protein signaling pathway													biological_process											owl:Class	
GO:0032332	biolink:NamedThing	positive regulation of chondrocyte differentiation	Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.	got7fsn_ti	upregulation of chondrocyte differentiation|stimulation of chondrocyte differentiation|activation of chondrocyte differentiation|up regulation of chondrocyte differentiation|up-regulation of chondrocyte differentiation													biological_process											owl:Class	
GO:0061036	biolink:NamedThing	positive regulation of cartilage development	Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	got7fsn_ti							dph	2010-02-09T03:41:35Z						biological_process											owl:Class	
GO:0050539	biolink:NamedThing	maleimide hydrolase activity	Catalysis of the reaction: H(2)O + maleimide = H(+) + maleamate.	got7fsn_ti	imidase activity|cyclic imide hydrolase activity|cyclic-imide amidohydrolase (decyclicizing)|cyclic-imide amidohydrolase (decyclizing)											KEGG_REACTION:R05781|MetaCyc:3.5.2.16-RXN|EC:3.5.2.16|RHEA:24476		molecular_function											owl:Class	
GO:0102739	biolink:NamedThing	(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate <=> H+ + gibberellin A4 + succinate + 2 carbon dioxide.	got7fsn_ti												MetaCyc:RXN-7591		molecular_function											owl:Class	
GO:0016236	biolink:NamedThing	macroautophagy	The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure.  Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.	got7fsn_ti	autophagy				Targeted macroautophagy sometimes targets regions of cytoplasm containing non-self, such as virus particles or components (e.g. see PMID:20159618).  As this is essentially the same process as macroautophagy that encloses and digests only self, the term autophagy is still used despite the enclosure of some non-self (non-auto) entities.						GO:0034262			biological_process											owl:Class	
GO:0042084	biolink:NamedThing	5-methyltetrahydrofolate-dependent methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.	got7fsn_ti														molecular_function											owl:Class	
GO:0000478	biolink:NamedThing	endonucleolytic cleavage involved in rRNA processing	Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA.	got7fsn_ti	endonucleolytic cleavage during rRNA processing													biological_process											owl:Class	
GO:0001519	biolink:NamedThing	peptide amidation	The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.	got7fsn_ti														biological_process											owl:Class	
GO:0031179	biolink:NamedThing	peptide modification	The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide.	got7fsn_ti														biological_process											owl:Class	
GO:0048624	biolink:NamedThing	plantlet formation on parent plant	The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed.	got7fsn_ti	vegetative vivipary|vivipary													biological_process											owl:Class	
GO:0061322	biolink:NamedThing	disseminated nephrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	got7fsn_ti							dph	2010-09-24T12:30:46Z						biological_process											owl:Class	
GO:0061319	biolink:NamedThing	nephrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	got7fsn_ti							dph	2010-09-24T12:23:29Z						biological_process											owl:Class	
GO:0061583	biolink:NamedThing	colon epithelial cell chemotaxis	The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti							dph	2013-12-23T07:46:57Z						biological_process											owl:Class	
GO:0080019	biolink:NamedThing	fatty-acyl-CoA reductase (alcohol-forming) activity	Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA.	got7fsn_ti	fatty acyl CoA reductase (alcohol-forming) activity|fatty acyl-CoA reductase (alcohol-forming) activity													molecular_function											owl:Class	
GO:0102594	biolink:NamedThing	cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-15372		molecular_function											owl:Class	
GO:0034007	biolink:NamedThing	S-linalool synthase activity	Catalysis of the reaction: geranyl diphosphate + H(2)O = (S)-linalool + diphosphate.	got7fsn_ti	3S-linalool synthase activity|geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming] activity|LIS											MetaCyc:4.2.3.25-RXN|RHEA:24116|EC:4.2.3.25|KEGG_REACTION:R07631		molecular_function											owl:Class	
GO:0080045	biolink:NamedThing	quercetin 3'-O-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0002308	biolink:NamedThing	CD8-positive, alpha-beta cytotoxic T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.	got7fsn_ti	CD8-positive, alpha-beta cytotoxic T cell development|CD8-positive, alpha-beta cytotoxic T-cell differentiation|CD8-positive, alpha-beta cytotoxic T-lymphocyte differentiation|CD8-positive, alpha-beta cytotoxic T lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0045065	biolink:NamedThing	cytotoxic T cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.	got7fsn_ti	cytotoxic T cell development|cytotoxic T-cell selection|cytotoxic T lymphocyte selection|cytotoxic T-lymphocyte selection				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0042171	biolink:NamedThing	lysophosphatidic acid acyltransferase activity	Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.	got7fsn_ti	LPAAT activity													molecular_function											owl:Class	
GO:0060654	biolink:NamedThing	mammary gland cord elongation	The process in which the mammary gland sprout grows along its axis.	got7fsn_ti							dph	2009-05-29T09:26:15Z						biological_process											owl:Class	
GO:0060751	biolink:NamedThing	branch elongation involved in mammary gland duct branching	The developmental growth process in which a branch of a mammary gland duct elongates.	got7fsn_ti	mammary gland duct branch elongation						dph	2009-06-22T11:02:44Z						biological_process											owl:Class	
GO:0050204	biolink:NamedThing	oxalomalate lyase activity	Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate.	got7fsn_ti	3-oxalomalate glyoxylate-lyase activity|3-oxalomalate glyoxylate-lyase (oxaloacetate-forming)											RHEA:22032|KEGG_REACTION:R00477|EC:4.1.3.13|MetaCyc:OXALOMALATE-LYASE-RXN		molecular_function											owl:Class	
GO:0007548	biolink:NamedThing	sex differentiation	The establishment of the sex of an organism by physical differentiation.	got7fsn_ti												Wikipedia:Sexual_differentiation		biological_process											owl:Class	
GO:0032466	biolink:NamedThing	negative regulation of cytokinesis	Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.	got7fsn_ti	negative regulation of cell cycle cytokinesis|downregulation of cytokinesis|down-regulation of cytokinesis|inhibition of cytokinesis|down regulation of cytokinesis										GO:0071776			biological_process											owl:Class	
GO:0000471	biolink:NamedThing	endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events.	got7fsn_ti														biological_process											owl:Class	
GO:0061765	biolink:NamedThing	modulation by virus of host NIK/NF-kappaB signaling	Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host.	got7fsn_ti							dph	2016-04-19T10:41:22Z						biological_process											owl:Class	
GO:0021583	biolink:NamedThing	pons morphogenesis	The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	got7fsn_ti														biological_process											owl:Class	
GO:0006269	biolink:NamedThing	DNA replication, synthesis of RNA primer	The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis.	got7fsn_ti	replication priming													biological_process											owl:Class	
GO:0032774	biolink:NamedThing	RNA biosynthetic process	The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.	got7fsn_ti	RNA biosynthesis|RNA formation|RNA synthesis|RNA anabolism				Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study.									biological_process											owl:Class	
GO:0009090	biolink:NamedThing	homoserine biosynthetic process	The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.	got7fsn_ti	homoserine biosynthesis|homoserine anabolism|homoserine synthesis|homoserine formation											MetaCyc:HOMOSERSYN-PWY		biological_process											owl:Class	
GO:0046725	biolink:NamedThing	negative regulation by virus of viral protein levels in host cell	Any process where the infecting virus reduces the levels of viral proteins in a cell.	got7fsn_ti	inhibition of viral protein levels in host cell|downregulation of viral protein levels in host cell|down regulation of viral protein levels in host cell|down-regulation of viral protein levels in host cell|negative regulation of viral protein levels													biological_process											owl:Class	
GO:0034858	biolink:NamedThing	2-hydroxybenzothiazole monooxygenase activity	Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole.	got7fsn_ti												UM-BBD_reactionID:r1291		molecular_function											owl:Class	
GO:0046093	biolink:NamedThing	deoxycytidine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.	got7fsn_ti	deoxycytidine synthesis|deoxycytidine anabolism|deoxycytidine formation|deoxycytidine biosynthesis													biological_process											owl:Class	
GO:0045932	biolink:NamedThing	negative regulation of muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.	got7fsn_ti	inhibition of muscle contraction|downregulation of muscle contraction|down regulation of muscle contraction|down-regulation of muscle contraction													biological_process											owl:Class	
GO:0002291	biolink:NamedThing	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell													biological_process											owl:Class	
GO:0010931	biolink:NamedThing	macrophage tolerance induction	A process involving any mechanism for tolerance induction in macrophages.	got7fsn_ti														biological_process											owl:Class	
GO:0071710	biolink:NamedThing	membrane macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell.	got7fsn_ti	membrane macromolecule anabolism|membrane macromolecule biosynthesis|membrane macromolecule synthesis|membrane macromolecule formation						mah	2010-03-10T11:29:52Z						biological_process											owl:Class	
GO:0070589	biolink:NamedThing	cellular component macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.	got7fsn_ti	cellular component macromolecule biosynthesis						mah	2009-04-28T11:01:25Z						biological_process											owl:Class	
GO:0034433	biolink:NamedThing	steroid esterification	A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol).	got7fsn_ti														biological_process											owl:Class	
GO:0102761	biolink:NamedThing	eriodictyol 3'-O-methyltransferase activity	Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine  <=> H+ + homoeriodictyol + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-7753|RHEA:60948		molecular_function											owl:Class	
GO:0001707	biolink:NamedThing	mesoderm formation	The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	got7fsn_ti														biological_process											owl:Class	
GO:0001704	biolink:NamedThing	formation of primary germ layer	The formation of the ectoderm, mesoderm and endoderm during gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0000451	biolink:NamedThing	rRNA 2'-O-methylation	The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:0031167	biolink:NamedThing	rRNA methylation	The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0031177	biolink:NamedThing	phosphopantetheine binding	Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).	got7fsn_ti														molecular_function											owl:Class	
GO:0080109	biolink:NamedThing	indole-3-acetonitrile nitrile hydratase activity	Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide.	got7fsn_ti							dhl	2009-04-23T04:37:57Z				KEGG_REACTION:R04020|MetaCyc:RXN-7567|EC:4.2.1.84		molecular_function											owl:Class	
GO:0075001	biolink:NamedThing	adhesion of symbiont infection structure to host	The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	attachment of symbiont infection structure to host|adhesion of symbiont infection structure to host during symbiotic interaction				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products of the symbiont involved in this process.									biological_process											owl:Class	
GO:0002420	biolink:NamedThing	natural killer cell mediated cytotoxicity directed against tumor cell target	The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.	got7fsn_ti	NK cell mediated cytotoxicity directed against tumor cell target				Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.									biological_process											owl:Class	
GO:0051550	biolink:NamedThing	aurone metabolic process	The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides.	got7fsn_ti	benzalcoumaran-3-one metabolism|benzalcoumaran-3-one metabolic process|aurone metabolism													biological_process											owl:Class	
GO:0042440	biolink:NamedThing	pigment metabolic process	The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.	got7fsn_ti	pigment metabolism													biological_process											owl:Class	
GO:0045926	biolink:NamedThing	negative regulation of growth	Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.	got7fsn_ti	downregulation of growth|inhibition of growth|down-regulation of growth|down regulation of growth													biological_process											owl:Class	
GO:0032472	biolink:NamedThing	Golgi calcium ion transport	The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus.	got7fsn_ti	Golgi calcium transport													biological_process											owl:Class	
GO:0006816	biolink:NamedThing	calcium ion transport	The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	calcium transport|sodium:calcium exchange|mitochondrial sodium/calcium ion exchange													biological_process											owl:Class	
GO:0044862	biolink:NamedThing	protein transport out of plasma membrane raft	The directed movement of a protein out of a plasma membrane raft.	got7fsn_ti							jl	2014-07-23T16:32:56Z						biological_process											owl:Class	
GO:0016460	biolink:NamedThing	myosin II complex	A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures.	got7fsn_ti	conventional myosin													cellular_component											owl:Class	
GO:0050595	biolink:NamedThing	7-deoxyloganin 7-hydroxylase activity	Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O.	got7fsn_ti	7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)											MetaCyc:1.14.13.74-RXN|RHEA:11452|EC:1.14.13.74		molecular_function											owl:Class	
GO:0032987	biolink:NamedThing	protein-lipid complex disassembly	The disaggregation of a protein-lipid complex into its constituent components.	got7fsn_ti														biological_process											owl:Class	
GO:0071825	biolink:NamedThing	protein-lipid complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.	got7fsn_ti	protein-lipid complex subunit organisation						mah	2010-09-08T10:04:36Z						biological_process											owl:Class	
GO:0102813	biolink:NamedThing	UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-(p-coumaroyl)-glucoside = shisonin + UDP + H+.	got7fsn_ti												MetaCyc:RXN-8205		molecular_function											owl:Class	
GO:2000167	biolink:NamedThing	regulation of planar cell polarity pathway involved in neural tube closure	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.	got7fsn_ti							dph	2010-10-05T01:08:53Z						biological_process											owl:Class	
GO:0090733	biolink:NamedThing	tenascin complex	A extracellular matrix complex involved in cell adhesion and cell migration. Typically homotrimeric or homohexameric. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R.	got7fsn_ti	Tenascin-R|Tenascin-X|Tenascin-C|Tenascin-W|Tenascin-N				An example is Tenascin-N (Q9UQP3) in PMID:17909022 (IDA).		tb	2017-02-01T16:29:55Z						cellular_component											owl:Class	
GO:0098637	biolink:NamedThing	protein complex involved in cell-matrix adhesion	Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion.	got7fsn_ti														cellular_component											owl:Class	
GO:0106147	biolink:NamedThing	fraxetin biosynthesis	The chemical reactions and pathways resulting in the formation of fraxetin.	got7fsn_ti							hjd	2018-09-07T18:32:47Z						biological_process											owl:Class	
GO:0009805	biolink:NamedThing	coumarin biosynthetic process	The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.	got7fsn_ti	coumarin anabolism|coumarin formation|coumarin biosynthesis|coumarin synthesis											MetaCyc:PWY-5176		biological_process											owl:Class	
GO:0031801	biolink:NamedThing	type 4 metabotropic glutamate receptor binding	Binding to a type 4 metabotropic glutamate receptor.	got7fsn_ti	type 4 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0007052	biolink:NamedThing	mitotic spindle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.	got7fsn_ti	mitotic spindle organization and biogenesis in nucleus|mitotic spindle organization and biogenesis|mitotic spindle organisation in nucleus|mitotic spindle organisation|spindle organization and biogenesis during mitosis|spindle organization and biogenesis in nucleus during mitosis|mitotic spindle organization in nucleus|mitotic spindle stabilization|mitotic spindle organization and biogenesis in cell nucleus	https://github.com/geneontology/go-ontology/issues/15341			In fission yeast most mitotic spindle organization occurs in the nucleus.						GO:0030472|GO:0000071|GO:0043148			biological_process											owl:Class	
GO:1902850	biolink:NamedThing	microtubule cytoskeleton organization involved in mitosis	Any microtubule cytoskeleton organization that is involved in mitosis.	got7fsn_ti	microtubule dynamics involved in mitosis|microtubule cytoskeleton organisation involved in mitosis|microtubule cytoskeleton organization and biogenesis involved in mitosis						vw	2014-04-02T14:19:38Z						biological_process											owl:Class	
GO:0017117	biolink:NamedThing	single-stranded DNA-dependent ATP-dependent DNA helicase complex	A protein complex that possesses single-stranded DNA-dependent DNA helicase activity.	got7fsn_ti	ssDNA-dependent ATP-dependent DNA helicase complex													cellular_component											owl:Class	
GO:0080163	biolink:NamedThing	regulation of protein serine/threonine phosphatase activity	Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.	got7fsn_ti	regulation of protein phosphatase type 2c activity						dhl	2010-09-23T03:51:37Z						biological_process											owl:Class	
GO:0043666	biolink:NamedThing	regulation of phosphoprotein phosphatase activity	Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein.	got7fsn_ti	regulation of protein phosphatase type 2A activity|regulation of protein phosphatase type 2B activity|regulation of protein phosphatase type 2 activity|regulation of calcineurin activity|regulation of protein phosphatase 3 activity										GO:0034047|GO:0032512			biological_process											owl:Class	
GO:1990767	biolink:NamedThing	prostaglandin receptor internalization	The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle.	got7fsn_ti							sl	2015-06-10T19:14:08Z						biological_process											owl:Class	
GO:0002031	biolink:NamedThing	G protein-coupled receptor internalization	The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.	got7fsn_ti	G-protein coupled receptor internalization													biological_process											owl:Class	
GO:0099111	biolink:NamedThing	microtubule-based transport	A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components.  Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.	got7fsn_ti														biological_process											owl:Class	
GO:0047089	biolink:NamedThing	dihydrochelirubine 12-monooxygenase activity	Catalysis of the reaction: dihydrochelirubine + H(+) + NADPH + O(2) = 12-hydroxydihydrochelirubine + H(2)O + NADP(+).	got7fsn_ti	dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)|dihydrochelirubine 12-hydroxylase activity											KEGG_REACTION:R04708|MetaCyc:1.14.13.57-RXN|EC:1.14.14.101|RHEA:10156		molecular_function											owl:Class	
GO:0106313	biolink:NamedThing	methylenetetrahydrofolate reductase NADPH activity	Catalysis of the reaction: 5-methyltetrahydrofolate + NADP + = 5,10-methylenetetrahydrofolate + NADPH + H+.	got7fsn_ti							hjd	2020-09-23T14:20:27Z				RHEA:19817		molecular_function											owl:Class	
GO:0004489	biolink:NamedThing	methylenetetrahydrofolate reductase (NAD(P)H) activity	Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.	got7fsn_ti	methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|5,10-CH2-H4folate reductase activity|MetF|5,10-methylenetetrahydropteroylglutamate reductase activity|5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|N(5),N(10)-methylenetetrahydrofolate reductase activity|N5,10-methylenetetrahydrofolate reductase activity|5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|5-methyltetrahydrofolate:NAD+ oxidoreductase activity|5-methyltetrahydrofolate:NAD oxidoreductase activity|5,10-methylenetetrahydrofolate reductase (NADPH) activity|methylenetetrahydrofolate reductase activity|methylenetetrahydrofolate reductase (NADPH(2)) activity|5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|MTHFR activity|5,10-CH(2)-H(4)folate reductase activity|5,10-methylenetetrahydrofolate reductase (FADH) activity|5-methyltetrahydrofolate:NADP+ oxidoreductase activity|methylenetetrahydrofolic acid reductase activity|5,10-methylenetetrahydrofolate reductase activity|methylenetetrahydrofolate reductase [NAD(P)H]|methylenetetrahydrofolate reductase (NADPH2)|methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|N5,N10-methylenetetrahydrofolate reductase activity|5,10-methylenetetrahydrofolate reductase (FADH2) activity|N(5,10)-methylenetetrahydrofolate reductase activity|5,10-methylenetetrahydrofolic acid reductase activity										GO:0008702	KEGG_REACTION:R01224|KEGG_REACTION:R07168|MetaCyc:1.5.1.20-RXN|Reactome:R-HSA-200676|EC:1.5.1.20		molecular_function											owl:Class	
GO:0070761	biolink:NamedThing	pre-snoRNP complex	A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.	got7fsn_ti	pre-small nucleolar ribonucleoprotein complex						mah	2009-06-23T02:32:10Z						cellular_component											owl:Class	
GO:0008399	biolink:NamedThing	naphthalene hydroxylase activity	Catalysis of the conversion of naphthalene to naphthalene 1,2-oxide.	got7fsn_ti	cytochrome P450 CYP2F2													molecular_function											owl:Class	
GO:1990359	biolink:NamedThing	stress response to zinc ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.	got7fsn_ti	response to zinc ion stress|response to zinc toxicity|stress response to zinc						kmv	2014-04-14T15:54:05Z						biological_process											owl:Class	
GO:0097501	biolink:NamedThing	stress response to metal ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus.	got7fsn_ti	response to excess metal ion|response to metal toxicity|response to metal ion stress|response to metal ion toxicity						pr	2013-08-15T10:37:45Z						biological_process											owl:Class	
GO:0002223	biolink:NamedThing	stimulatory C-type lectin receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation.	got7fsn_ti	stimulatory Ly49 family receptor signaling pathway|stimulatory C-type lectin receptor signalling pathway													biological_process											owl:Class	
GO:1990858	biolink:NamedThing	cellular response to lectin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.	got7fsn_ti					This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity.		sl	2015-09-24T15:34:42Z						biological_process											owl:Class	
GO:0090110	biolink:NamedThing	COPII-coated vesicle cargo loading	The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.	got7fsn_ti	cargo loading into COPII-coated vesicle|cargo loading into COPII vesicle|cargo selection into COPII-coated vesicle|COPII coat-cargo complex assembly						tb	2009-12-06T08:28:34Z						biological_process											owl:Class	
GO:0008397	biolink:NamedThing	sterol 12-alpha-hydroxylase activity	Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O.	got7fsn_ti	cytochrome P450 CYP8B1													molecular_function											owl:Class	
GO:0090463	biolink:NamedThing	lysine homeostasis	Any process involved in the maintenance of an internal steady state of lysine within an organism or cell.	got7fsn_ti							tb	2012-09-24T14:22:02Z						biological_process											owl:Class	
GO:0009513	biolink:NamedThing	etioplast	A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.	got7fsn_ti												Wikipedia:Etioplast		cellular_component											owl:Class	
GO:0080090	biolink:NamedThing	regulation of primary metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.	got7fsn_ti							dhl	2009-04-22T04:30:52Z						biological_process											owl:Class	
GO:0097685	biolink:NamedThing	dinoflagellate apical groove	A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex.	got7fsn_ti	apical groove				The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-12-18T09:34:52Z						cellular_component											owl:Class	
GO:0004112	biolink:NamedThing	cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0000032	biolink:NamedThing	cell wall mannoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.	got7fsn_ti	cell wall mannoprotein synthesis|cell wall mannoprotein anabolism|cell wall mannoprotein formation|cell wall mannoprotein biosynthesis													biological_process											owl:Class	
GO:0006057	biolink:NamedThing	mannoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of a mannoprotein, a protein that contains covalently bound mannose residues.	got7fsn_ti	mannoprotein anabolism|mannoprotein biosynthesis|mannoprotein synthesis|mannoprotein formation													biological_process											owl:Class	
GO:0048358	biolink:NamedThing	mucilage pectin biosynthetic process	The chemical reactions and pathways resulting in the formation of the pectin component of mucilage.	got7fsn_ti	mucilage pectin formation|mucilage pectin synthesis|mucilage pectin anabolism|mucilage pectin biosynthesis													biological_process											owl:Class	
GO:0045489	biolink:NamedThing	pectin biosynthetic process	The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.	got7fsn_ti	pectin formation|pectin anabolism|pectin synthesis|pectin biosynthesis													biological_process											owl:Class	
GO:0035100	biolink:NamedThing	ecdysone binding	Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.	got7fsn_ti														molecular_function											owl:Class	
GO:0061413	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	got7fsn_ti							dph	2012-01-23T11:13:06Z						biological_process											owl:Class	
GO:0008897	biolink:NamedThing	holo-[acyl-carrier-protein] synthase activity	Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.	got7fsn_ti	phosphopantetheinyl transferase|acyl carrier protein holoprotein (holo-ACP) synthetase activity|acyl carrier protein synthase activity|P-pant transferase activity|holo-ACP synthase activity|holo-ACP synthetase activity|coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity|phosphopantetheinyltransferase activity|4'-phosphopantetheinyltransferase activity|holo-[peptidyl-carrier protein] synthase activity|alpha-aminoadipate reductase phosphopantetheinyl transferase activity|PPTase activity|CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity|alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|ACPS activity|acyl carrier protein synthetase activity|CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity|holo-[acyl-carrier-protein] synthase activity|4'-phosphopantetheinyl transferase activity|alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|holosynthase activity|L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|AcpS|holo-acyl-carrier-protein synthase activity	https://github.com/geneontology/go-ontology/issues/18113									GO:0008958	MetaCyc:HOLO-ACP-SYNTH-RXN|EC:2.7.8.7|Reactome:R-HSA-199202|RHEA:12068		molecular_function											owl:Class	
GO:0098601	biolink:NamedThing	selenomethionine adenosyltransferase activity	Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine.	got7fsn_ti							dos	2014-04-15T15:15:03Z				Reactome:R-HSA-2408551|RHEA:31211		molecular_function											owl:Class	
GO:0021788	biolink:NamedThing	chemoattraction of branchiomotor neuron axon in neural tube	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti	positive chemotaxis of branchiomotor neuron axon in neural tube													biological_process											owl:Class	
GO:0021792	biolink:NamedThing	chemoattraction of branchiomotor axon	The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti	positive chemotaxis of branchiomotor axon													biological_process											owl:Class	
GO:0071598	biolink:NamedThing	neuronal ribonucleoprotein granule	A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli.	got7fsn_ti	neuronal RNA granule|neuronal RNP granule						mah	2010-02-04T04:01:57Z						cellular_component											owl:Class	
GO:0036464	biolink:NamedThing	cytoplasmic ribonucleoprotein granule	A ribonucleoprotein granule located in the cytoplasm.	got7fsn_ti	Staufen granule						bf	2014-06-18T09:44:44Z						cellular_component											owl:Class	
GO:0097082	biolink:NamedThing	vascular associated smooth muscle cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	got7fsn_ti	vascular smooth muscle cell fate specification						pr	2011-06-20T03:56:21Z						biological_process											owl:Class	
GO:0042694	biolink:NamedThing	muscle cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0097280	biolink:NamedThing	histamine secretion mediated by immunoglobulin	Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.	got7fsn_ti							pr	2012-03-26T01:30:25Z						biological_process											owl:Class	
GO:0002437	biolink:NamedThing	inflammatory response to antigenic stimulus	An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.	got7fsn_ti														biological_process											owl:Class	
GO:0002630	biolink:NamedThing	positive regulation of proteolysis associated with antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.	got7fsn_ti	stimulation of proteolysis associated with antigen processing and presentation|activation of proteolysis associated with antigen processing and presentation|upregulation of proteolysis associated with antigen processing and presentation|up-regulation of proteolysis associated with antigen processing and presentation|up regulation of proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0045732	biolink:NamedThing	positive regulation of protein catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	got7fsn_ti	positive regulation of protein degradation|up regulation of protein catabolic process|activation of protein catabolic process|positive regulation of protein breakdown|upregulation of protein catabolic process|up-regulation of protein catabolic process|stimulation of protein catabolic process|positive regulation of protein catabolism													biological_process											owl:Class	
GO:0009777	biolink:NamedThing	photosynthetic phosphorylation	Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation.	got7fsn_ti	photosynthetic ATP synthesis													biological_process											owl:Class	
GO:0016310	biolink:NamedThing	phosphorylation	The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.	got7fsn_ti												Wikipedia:Phosphorylation		biological_process											owl:Class	
GO:0047547	biolink:NamedThing	2-methylcitrate dehydratase activity	Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.	got7fsn_ti	prpD|2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity|2-methylcitrate hydro-lyase activity|(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]											RHEA:17725|EC:4.2.1.79|KEGG_REACTION:R04424|MetaCyc:2-METHYLCITRATE-DEHYDRATASE-RXN		molecular_function											owl:Class	
GO:0021688	biolink:NamedThing	cerebellar molecular layer formation	The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	got7fsn_ti														biological_process											owl:Class	
GO:0047410	biolink:NamedThing	N-formylmethionylaminoacyl-tRNA deformylase activity	Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate.	got7fsn_ti	N-formyl-L-methionylaminoacyl-tRNA amidohydrolase activity											MetaCyc:3.5.1.27-RXN		molecular_function											owl:Class	
GO:0010178	biolink:NamedThing	IAA-amino acid conjugate hydrolase activity	Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0018274	biolink:NamedThing	peptide cross-linking via L-lysinoalanine	The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link.	got7fsn_ti												RESID:AA0123		biological_process											owl:Class	
GO:0021772	biolink:NamedThing	olfactory bulb development	The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.	got7fsn_ti														biological_process											owl:Class	
GO:1990729	biolink:NamedThing	primary miRNA modification	The covalent alteration of one or more nucleotides within a primary miRNA molecule to produce a primary miRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti							sp	2015-04-16T06:19:22Z						biological_process											owl:Class	
GO:0046896	biolink:NamedThing	N-terminal peptidyl-leucine methylation	The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine.	got7fsn_ti												RESID:AA0337		biological_process											owl:Class	
GO:0052892	biolink:NamedThing	aromatic (S)-hydroxynitrile lyase activity	Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide.	got7fsn_ti	(S)-hydroxynitrile lyase activity|(S)-cyanohydrin producing hydroxynitrile lyase activity|(S)-oxynitrilase activity|(S)-selective hydroxynitrile lyase activity|hydroxynitrile lyase activity|oxynitrilase activity|(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity											MetaCyc:RXN-11732|RHEA:54660|EC:4.1.2.47|KEGG_REACTION:R09359		molecular_function											owl:Class	
GO:0008733	biolink:NamedThing	L-arabinose isomerase activity	Catalysis of the reaction: L-arabinose = L-ribulose.	got7fsn_ti	L-arabinose ketol-isomerase activity|L-arabinose aldose-ketose-isomerase activity											RHEA:14821|EC:5.3.1.4|KEGG_REACTION:R01761|MetaCyc:ARABISOM-RXN		molecular_function											owl:Class	
GO:1990099	biolink:NamedThing	pre-primosome complex	Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component.	got7fsn_ti	pre-primosome|pre-priming complex|preprimosome|prereplication complex|preprimosome complex|pre-replication complex						bhm	2013-05-14T10:53:42Z						cellular_component											owl:Class	
GO:0070553	biolink:NamedThing	nicotinic acid receptor activity	Combining with nicotinic acid to initiate a change in cell activity.	got7fsn_ti	niacin receptor activity													molecular_function											owl:Class	
GO:0070711	biolink:NamedThing	RNA adenosine-uridine insertion	The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide.	got7fsn_ti	RNA AU insertion						mah	2009-06-08T05:16:39Z						biological_process											owl:Class	
GO:0070707	biolink:NamedThing	RNA dinucleotide insertion	The modification of an RNA molecule by insertion of a dinucleotide.	got7fsn_ti							mah	2009-06-08T04:50:59Z						biological_process											owl:Class	
GO:0106369	biolink:NamedThing	GTP dependent (deoxy)nucleoside -phosphate kinase activity	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + GTP = a 2'-deoxyribonucleoside 5'-diphosphate + GDP.	got7fsn_ti							hjd	2021-03-11T20:12:21Z				RHEA:62124		molecular_function											owl:Class	
GO:0033933	biolink:NamedThing	branched-dextran exo-1,2-alpha-glucosidase activity	Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.	got7fsn_ti	dextran alpha-1,2 debranching enzyme|1,2-alpha-D-glucosyl-branched-dextran 2-glucohydrolase activity|dextran 1,2-alpha-glucosidase activity											MetaCyc:3.2.1.115-RXN|EC:3.2.1.115		molecular_function											owl:Class	
GO:0099557	biolink:NamedThing	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0070845	biolink:NamedThing	polyubiquitinated misfolded protein transport	The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.	got7fsn_ti	misfolded polyubiquitinated protein transport|polyubiquitylated misfolded protein transport						mah	2009-07-31T12:52:26Z						biological_process											owl:Class	
GO:0070844	biolink:NamedThing	polyubiquitinated protein transport	The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.	got7fsn_ti	polyubiquitylated protein transport						mah	2009-07-31T12:51:10Z						biological_process											owl:Class	
GO:0052335	biolink:NamedThing	modification by host of symbiont cytoskeleton	The process in which an organism effects a change in the structure or function of the symbiont cytoskeleton. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0052187	biolink:NamedThing	modification by host of symbiont cellular component	The process in which an organism effects a change in the structure or function of a symbiont cellular component. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:1990502	biolink:NamedThing	dense core granule maturation	Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.	got7fsn_ti	dense core vesicle maturation						kmv	2014-09-30T20:35:11Z						biological_process											owl:Class	
GO:0050503	biolink:NamedThing	trehalose 6-phosphate phosphorylase activity	Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate.	got7fsn_ti	trehalose 6-phosphate:phosphate beta-D-glucosyltransferase activity											RHEA:20864|MetaCyc:2.4.1.216-RXN|EC:2.4.1.216		molecular_function											owl:Class	
GO:0014063	biolink:NamedThing	negative regulation of serotonin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.	got7fsn_ti	downregulation of serotonin secretion|down regulation of serotonin secretion|down-regulation of serotonin secretion|inhibition of serotonin secretion|positive regulation of serotonin release													biological_process											owl:Class	
GO:0097502	biolink:NamedThing	mannosylation	The covalent attachment of a mannose residue to a substrate molecule.	got7fsn_ti							pr	2013-09-20T09:47:40Z						biological_process											owl:Class	
GO:0070085	biolink:NamedThing	glycosylation	The covalent attachment and further modification of carbohydrate residues to a substrate molecule.	got7fsn_ti												Wikipedia:Glycosylation		biological_process											owl:Class	
GO:0075713	biolink:NamedThing	establishment of integrated proviral latency	A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.	got7fsn_ti	provirus integration|prophage integration						jl	2009-05-07T02:28:41Z			GO:0019047	VZ:980		biological_process											owl:Class	
GO:0019043	biolink:NamedThing	establishment of viral latency	A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects.	got7fsn_ti	phage lysogeny|lysogenic commitment										GO:0075601			biological_process											owl:Class	
GO:0010036	biolink:NamedThing	response to boron-containing substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus.	got7fsn_ti	response to boron													biological_process											owl:Class	
GO:1990457	biolink:NamedThing	pexophagosome	A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy.	got7fsn_ti							dhl	2014-08-15T18:51:53Z						cellular_component											owl:Class	
GO:0045335	biolink:NamedThing	phagocytic vesicle	A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.	got7fsn_ti	phagosome											Wikipedia:Phagosome		cellular_component											owl:Class	
GO:0006696	biolink:NamedThing	ergosterol biosynthetic process	The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.	got7fsn_ti	ergosterol biosynthesis|ergosterol anabolism|ergosterol synthesis|ergosterol formation													biological_process											owl:Class	
GO:0042242	biolink:NamedThing	cobyrinic acid a,c-diamide synthase activity	Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide.	got7fsn_ti	cobyrinate a,c-diamide synthase activity|CobB|cobyrinate a,c diamide synthase activity|cobyrinate a c diamide synthase activity|cobyrinate a c-diamide synthase activity										GO:0043775	RHEA:26289|EC:6.3.5.11		molecular_function											owl:Class	
GO:0016884	biolink:NamedThing	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16422									GO:0016003	EC:6.3.5.-		molecular_function											owl:Class	
GO:0060201	biolink:NamedThing	clathrin-sculpted acetylcholine transport vesicle membrane	The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle.	got7fsn_ti	clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle membrane|clathrin sculpted acetylcholine transport vesicle membrane													cellular_component											owl:Class	
GO:0045247	biolink:NamedThing	cytosolic electron transfer flavoprotein complex	A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors.	got7fsn_ti														cellular_component											owl:Class	
GO:0061652	biolink:NamedThing	FAT10 conjugating enzyme activity	Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y -> Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2						dph	2014-11-06T13:21:50Z						molecular_function											owl:Class	
GO:0051707	biolink:NamedThing	response to other organism	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.	got7fsn_ti											GO:0042828|GO:0009613			biological_process											owl:Class	
GO:0031787	biolink:NamedThing	H9 melatonin receptor binding	Binding to a H9 melatonin receptor.	got7fsn_ti	H9 melatonin receptor ligand													molecular_function											owl:Class	
GO:0008311	biolink:NamedThing	double-stranded DNA 3'-5' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule.	got7fsn_ti	double-stranded DNA specific 3'-5' exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0120325	biolink:NamedThing	NuRD complex binding	Binding to a NuRD complex.	got7fsn_ti							krc	2021-08-03T21:15:31Z						molecular_function											owl:Class	
GO:0070700	biolink:NamedThing	BMP receptor binding	Binding to a BMP receptor.	got7fsn_ti	bone morphogenetic protein receptor binding						mah	2009-06-04T04:24:16Z						molecular_function											owl:Class	
GO:0043116	biolink:NamedThing	negative regulation of vascular permeability	Any process that reduces the extent to which blood vessels can be pervaded by fluid.	got7fsn_ti	down regulation of vascular permeability|downregulation of vascular permeability|down-regulation of vascular permeability|inhibition of vascular permeability													biological_process											owl:Class	
GO:0003029	biolink:NamedThing	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.	got7fsn_ti	detection of hypoxic conditions in blood by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0034925	biolink:NamedThing	pyrene 4,5-monooxygenase activity	Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O.	got7fsn_ti												UM-BBD_reactionID:r0941		molecular_function											owl:Class	
GO:0102263	biolink:NamedThing	tRNA-dihydrouridine17 synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) <=> H+ + a uracil17 in tRNA + NAD(P)H.	got7fsn_ti												EC:1.3.1.88|MetaCyc:RXN-12455		molecular_function											owl:Class	
GO:0050110	biolink:NamedThing	mucinaminylserine mucinaminidase activity	Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine.	got7fsn_ti	endo-beta-N-acetyl-D-galactosaminidase activity|endo-beta-N-acetylgalactosaminidase|D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase activity											MetaCyc:3.2.1.110-RXN|KEGG_REACTION:R04527|EC:3.2.1.97		molecular_function											owl:Class	
GO:0035489	biolink:NamedThing	guanine/guanine mispair binding	Binding to a double-stranded DNA region containing a G/G mispair.	got7fsn_ti	G/G mispair binding						bf	2010-04-23T11:16:55Z						molecular_function											owl:Class	
GO:0070946	biolink:NamedThing	neutrophil-mediated killing of gram-positive bacterium	The directed killing of a gram-positive bacterium by a neutrophil.	got7fsn_ti	neutrophil mediated killing of gram-positive bacterium						mah	2009-10-01T02:04:15Z						biological_process											owl:Class	
GO:0050700	biolink:NamedThing	CARD domain binding	Binding to a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.	got7fsn_ti														molecular_function											owl:Class	
GO:0001567	biolink:NamedThing	cholesterol 25-hydroxylase activity	Catalysis of the reaction: AH(2) + cholesterol + O(2) = 25-hydroxycholesterol + A + H(2)O.	got7fsn_ti	cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity|cholesterol 25-monooxygenase activity											EC:1.14.99.38|RHEA:21104|KEGG_REACTION:R07218|MetaCyc:1.14.99.38-RXN		molecular_function											owl:Class	
GO:0070089	biolink:NamedThing	chloride-activated potassium channel activity	Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.	got7fsn_ti														molecular_function											owl:Class	
GO:0050294	biolink:NamedThing	steroid sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate.	got7fsn_ti	3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase activity|steroid alcohol sulfotransferase|steroid sulphotransferase activity											Reactome:R-HSA-176521|EC:2.8.2.15|MetaCyc:STEROID-SULFOTRANSFERASE-RXN|Reactome:R-HSA-176517|Reactome:R-HSA-176631		molecular_function											owl:Class	
GO:0045939	biolink:NamedThing	negative regulation of steroid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.	got7fsn_ti	down-regulation of steroid metabolic process|downregulation of steroid metabolic process|down regulation of steroid metabolic process|inhibition of steroid metabolic process|negative regulation of steroid metabolism													biological_process											owl:Class	
GO:0019218	biolink:NamedThing	regulation of steroid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.	got7fsn_ti	regulation of steroid metabolism													biological_process											owl:Class	
GO:0043293	biolink:NamedThing	apoptosome	A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.	got7fsn_ti												Wikipedia:Apoptosome		cellular_component											owl:Class	
GO:0044675	biolink:NamedThing	formyl-methanofuran dehydrogenase (tungsten enzyme) complex	A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.	got7fsn_ti							jl	2012-08-09T10:54:49Z						cellular_component											owl:Class	
GO:0036414	biolink:NamedThing	histone citrullination	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein.	got7fsn_ti	histone deimination						bf	2013-08-22T14:04:26Z						biological_process											owl:Class	
GO:0015979	biolink:NamedThing	photosynthesis	The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.	got7fsn_ti												Wikipedia:Photosynthesis		biological_process											owl:Class	
GO:0050277	biolink:NamedThing	sedoheptulokinase activity	Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate.	got7fsn_ti	ATP:sedoheptulose 7-phosphotransferase activity|sedoheptulokinase (phosphorylating)|heptulokinase activity											RHEA:23844|Reactome:R-HSA-8959719|KEGG_REACTION:R01844|EC:2.7.1.14|MetaCyc:SEDOHEPTULOKINASE-RXN		molecular_function											owl:Class	
GO:0102446	biolink:NamedThing	rhamnetin 3-O-methyltransferase activity	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine  <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-13932		molecular_function											owl:Class	
GO:0021954	biolink:NamedThing	central nervous system neuron development	The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.	got7fsn_ti														biological_process											owl:Class	
GO:0048666	biolink:NamedThing	neuron development	The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0002413	biolink:NamedThing	tolerance induction to tumor cell	A process of tolerance induction which leads to immunological tolerance of a tumor.	got7fsn_ti														biological_process											owl:Class	
GO:0002465	biolink:NamedThing	peripheral tolerance induction	Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0031766	biolink:NamedThing	type 3 galanin receptor binding	Binding to a type 3 galanin receptor.	got7fsn_ti	type 3 galanin receptor ligand													molecular_function											owl:Class	
GO:0031763	biolink:NamedThing	galanin receptor binding	Binding to a galanin receptor.	got7fsn_ti	galanin receptor ligand													molecular_function											owl:Class	
GO:0043898	biolink:NamedThing	2,3-dihydroxybiphenyl 1,2-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.	got7fsn_ti	2,3-dihydroxybiphenyl-1,2-dioxygenase activity|BphC													molecular_function											owl:Class	
GO:0043532	biolink:NamedThing	angiostatin binding	Binding to angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis.	got7fsn_ti														molecular_function											owl:Class	
GO:0140358	biolink:NamedThing	P-type transmembrane transporter activity	Primary active transporter that auto-phosphorylates (hence P) at a key conserved aspartate residue, generating a conformational change that allows transport of the substrate. Hydrolysis of the phosphorylated Asp residue, catalyzed by the actuator (A) domain, results in another state with occluded substrates. Upon dissociation of Mg2+ and inorganic phosphate (Pi), the enzyme reverts to the initial state, in which the counter-transported substrate is released into the cytosol.	got7fsn_ti	E1-E2 ATPase|P-type ATPase	https://github.com/geneontology/go-ontology/issues/21273|https://github.com/geneontology/go-ontology/issues/20529					pg	2019-06-25T19:07:46Z				TC:3.A.3|Wikipedia:P-type_ATPase		molecular_function											owl:Class	
GO:0042626	biolink:NamedThing	ATPase-coupled transmembrane transporter activity	Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.	got7fsn_ti	P-P-bond-hydrolysis-driven transporter|ATPase activity, coupled to movement of substances|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|P-P-bond-hydrolysis-driven transmembrane transporter activity|ATP-dependent transmembrane transporter activity|ATP-coupled transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of substances	https://github.com/geneontology/go-ontology/issues/19965|https://github.com/geneontology/go-ontology/issues/17373|https://github.com/geneontology/go-ontology/issues/14642									GO:0016820|GO:0043492|GO:0015405	Reactome:R-HSA-2161506|Reactome:R-HSA-1467457|Reactome:R-HSA-9033505|Reactome:R-HSA-2161538|Reactome:R-HSA-9033499		molecular_function											owl:Class	
GO:0097557	biolink:NamedThing	right posteriolateral flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body.	got7fsn_ti	right posterolateral flagellum|right posterolateral cilium|right posteriolateral cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:24:55Z						cellular_component											owl:Class	
GO:0052029	biolink:NamedThing	suppression by symbiont of host signal transduction pathway	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of signal transduction in other organism involved in symbiotic interaction|negative regulation by symbiont of host signal transduction pathway|inhibition by symbiont of host signal transduction pathway|down regulation by symbiont of host signal transduction pathway|down-regulation by symbiont of host signal transduction pathway|negative modulation by organism of host signal transduction pathway|downregulation by symbiont of host signal transduction pathway										GO:0052493			biological_process											owl:Class	
GO:0032441	biolink:NamedThing	pheophorbide a oxygenase activity	Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O.	got7fsn_ti												MetaCyc:RXN-7740|RHEA:48140|EC:1.14.15.17		molecular_function											owl:Class	
GO:0016730	biolink:NamedThing	oxidoreductase activity, acting on iron-sulfur proteins as donors	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on iron-sulphur proteins as donors											EC:1.18.-.-		molecular_function											owl:Class	
GO:0043812	biolink:NamedThing	phosphatidylinositol-4-phosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate.	got7fsn_ti	phosphatidylinositol 4-phosphate phosphatase activity													molecular_function											owl:Class	
GO:0052744	biolink:NamedThing	phosphatidylinositol monophosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate.	got7fsn_ti							ai	2011-09-14T01:36:39Z						molecular_function											owl:Class	
GO:0080014	biolink:NamedThing	thalianol hydroxylase activity	Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X.	got7fsn_ti					In Field and Osbourn 2008 (PMID:18356490), thalianol is referred to as (3S,13S,3R)-malabarica-8,17,21-trien-3-ol and thalian-diol is referred to as (3S,13S,14R)-malabarica-8,17,21-trien-3,?-diol, but the error in this naming system was pointed out in Kolesnikova 2007 (PMID:17474751). The new names used in the definition have been approved by the authors (Field and Osbourn 2008).							EC:1.14.13.-|MetaCyc:RXN-9631		molecular_function											owl:Class	
GO:0061836	biolink:NamedThing	intranuclear rod	A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions.	got7fsn_ti	intranuclear actin rod													cellular_component											owl:Class	
GO:0099512	biolink:NamedThing	supramolecular fiber	A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.	got7fsn_ti	fibril										GO:0043205			cellular_component											owl:Class	
GO:0047087	biolink:NamedThing	protopine 6-monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + protopine = 6-hydroxyprotopine + H(2)O + NADP(+).	got7fsn_ti	protopine 6-hydroxylase activity|protopine,NADPH:oxygen oxidoreductase (6-hydroxylating)											EC:1.14.14.98|RHEA:22644|MetaCyc:1.14.13.55-RXN|KEGG_REACTION:R04699		molecular_function											owl:Class	
GO:0001501	biolink:NamedThing	skeletal system development	The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).	got7fsn_ti	skeletal development													biological_process											owl:Class	
GO:0021938	biolink:NamedThing	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells.	got7fsn_ti	hh signaling pathway involved in regulation of granule cell precursor cell proliferation|hedgehog signaling pathway involved in regulation of granule cell precursor cell proliferation|smoothened signalling pathway in regulation of granule cell precursor cell proliferation													biological_process											owl:Class	
GO:0007224	biolink:NamedThing	smoothened signaling pathway	A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.	got7fsn_ti	hh signaling pathway|smoothened signalling pathway|Sonic hedgehog signaling pathway|hedgehog signaling pathway|hh signalling pathway|Shh signaling pathway											Wikipedia:Hedgehog_signaling_pathway		biological_process											owl:Class	
GO:0014744	biolink:NamedThing	positive regulation of muscle adaptation	Any process that activates or increases the frequency, rate or extent of muscle adaptation.	got7fsn_ti	positive regulation of muscle plasticity													biological_process											owl:Class	
GO:0010137	biolink:NamedThing	ureide biosynthetic process	The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots.	got7fsn_ti	ureide biosynthesis|ureide synthesis|ureide anabolism|ureide formation											MetaCyc:URSIN-PWY		biological_process											owl:Class	
GO:0010135	biolink:NamedThing	ureide metabolic process	The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants.	got7fsn_ti	ureide metabolism													biological_process											owl:Class	
GO:1990892	biolink:NamedThing	mitotic chromosome arm condensation	The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells.	got7fsn_ti							vw	2015-11-03T14:16:59Z						biological_process											owl:Class	
GO:0007076	biolink:NamedThing	mitotic chromosome condensation	The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.	got7fsn_ti														biological_process											owl:Class	
GO:0140691	biolink:NamedThing	RNA folding chaperone	Binding to an RNA or an RNA-containing complex to assist the folding process.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21913					pg	2021-08-04T07:48:29Z						molecular_function											owl:Class	
GO:0018707	biolink:NamedThing	1-phenanthrol methyltransferase activity	Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene.	got7fsn_ti												UM-BBD_reactionID:r0493		molecular_function											owl:Class	
GO:0018852	biolink:NamedThing	dichloromuconate cycloisomerase activity	Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.	got7fsn_ti	2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)											MetaCyc:DICHLOROMUCONATE-CYCLOISOMERASE-RXN|EC:5.5.1.11|UM-BBD_reactionID:r0277|RHEA:17437		molecular_function											owl:Class	
GO:0047096	biolink:NamedThing	androst-4-ene-3,17-dione monooxygenase activity	Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O(2) = A + H(2)O + testololactone.	got7fsn_ti	androst-4-ene-3,17-dione 17-oxidoreductase activity|androst-4-ene-3,17-dione hydroxylase activity|androstene-3,17-dione hydroxylase activity|4-androstene-3,17-dione monooxygenase activity|androst-4-ene-3,17-dione-hydrogen-donor:oxygen oxidoreductase (13-hydroxylating, lactonizing)|androstenedione monooxygenase activity											KEGG_REACTION:R01833|RHEA:22696|EC:1.14.99.12|MetaCyc:1.14.99.12-RXN		molecular_function											owl:Class	
GO:0035149	biolink:NamedThing	lumen formation, open tracheal system	Creation of the central hole of a tube in an open tracheal system through which gases flow.	got7fsn_ti	tracheal lumen formation													biological_process											owl:Class	
GO:0035148	biolink:NamedThing	tube formation	Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.	got7fsn_ti	tube lumen formation|lumen formation in an anatomical structure													biological_process											owl:Class	
GO:0042428	biolink:NamedThing	serotonin metabolic process	The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	got7fsn_ti	serotonin metabolism													biological_process											owl:Class	
GO:0018020	biolink:NamedThing	peptidyl-glutamic acid methylation	The addition of a methyl group to a glutamic acid residue in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0048054	biolink:NamedThing	R2/R5 cell differentiation	The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0080177	biolink:NamedThing	plastoglobule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.	got7fsn_ti	plastoglobule organisation						dhl	2011-04-28T04:13:07Z						biological_process											owl:Class	
GO:0097378	biolink:NamedThing	dorsal spinal cord interneuron axon guidance	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord.	got7fsn_ti	dorsal interneuron axon guidance						pr	2012-10-01T10:20:48Z						biological_process											owl:Class	
GO:0120135	biolink:NamedThing	distal portion of axoneme	The portion of the axoneme that is close to the tip of the cilium.	got7fsn_ti	distal part of axoneme						krc	2018-03-10T01:45:34Z						cellular_component											owl:Class	
GO:0070207	biolink:NamedThing	protein homotrimerization	The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.	got7fsn_ti	protein homotrimer assembly|protein homotrimer biosynthetic process|protein homotrimer formation|protein homotrimer biosynthesis													biological_process											owl:Class	
GO:0047820	biolink:NamedThing	D-glutamate cyclase activity	Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H(2)O.	got7fsn_ti	D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)|D-glutamate hydro-lyase (cyclizing)											RHEA:22360|MetaCyc:D-GLUTAMATE-CYCLASE-RXN|EC:4.2.1.48|KEGG_REACTION:R01583		molecular_function											owl:Class	
GO:0048647	biolink:NamedThing	polyphenic determination	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues.	got7fsn_ti														biological_process											owl:Class	
GO:0035700	biolink:NamedThing	astrocyte chemotaxis	The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti							bf	2011-02-28T03:17:52Z						biological_process											owl:Class	
GO:0047350	biolink:NamedThing	glucuronate-1-phosphate uridylyltransferase activity	Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate.	got7fsn_ti	UTP:1-phospho-alpha-D-glucuronate uridylyltransferase activity|UDP-D-glucuronic acid pyrophosphorylase activity|uridine diphosphoglucuronic pyrophosphorylase activity|UTP:glucuronate-1-phosphate uridylyltransferase activity|UDP-glucuronic acid pyrophosphorylase activity|UDP-glucuronate pyrophosphorylase activity											KEGG_REACTION:R01381|RHEA:16325|EC:2.7.7.44|MetaCyc:2.7.7.44-RXN		molecular_function											owl:Class	
GO:0070569	biolink:NamedThing	uridylyltransferase activity	Catalysis of the transfer of an uridylyl group to an acceptor.	got7fsn_ti	uridyl transferase activity|uridyltransferase activity						mah	2009-04-15T11:06:07Z						molecular_function											owl:Class	
GO:0046691	biolink:NamedThing	intracellular canaliculus	An apical plasma membrane part that forms a narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates.	got7fsn_ti	canalicular membrane													cellular_component											owl:Class	
GO:0072093	biolink:NamedThing	metanephric renal vesicle formation	The developmental process pertaining to the initial formation of the metanephros.	got7fsn_ti	metanephros formation						mah	2010-02-10T01:17:11Z						biological_process											owl:Class	
GO:0072033	biolink:NamedThing	renal vesicle formation	The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.	got7fsn_ti	nephron epithelium formation						mah	2010-01-25T02:57:03Z						biological_process											owl:Class	
GO:0035593	biolink:NamedThing	positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region	Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region.	got7fsn_ti	positive regulation of Wnt receptor signalling pathway by establishment of Wnt protein localization in extracellular region|positive regulation of Wnt signaling range|positive regulation of Wnt diffusion|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization in extracellular region|positive regulation of Wnt-activated signaling pathway by establishment of Wnt protein localization to extracellular region|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localisation in extracellular region|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization to extracellular region						bf	2010-11-09T10:29:44Z						biological_process											owl:Class	
GO:0060406	biolink:NamedThing	positive regulation of penile erection	Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.	got7fsn_ti														biological_process											owl:Class	
GO:0060405	biolink:NamedThing	regulation of penile erection	Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.	got7fsn_ti														biological_process											owl:Class	
GO:0110120	biolink:NamedThing	gamma-tubulin complex localization to nuclear side of mitotic spindle pole body	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body.	got7fsn_ti							kmv	2018-07-27T15:42:46Z						biological_process											owl:Class	
GO:0102560	biolink:NamedThing	5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity	Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> D-ribofuranose 2,5-bisphosphate + H+.	got7fsn_ti	phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase											EC:3.1.4.57|RHEA:41612|MetaCyc:RXN-14995		molecular_function											owl:Class	
GO:0047292	biolink:NamedThing	trihydroxypterocarpan dimethylallyltransferase activity	Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate.	got7fsn_ti	dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase activity|dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity|dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity|dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethyltransferase activity											EC:2.5.1.36|MetaCyc:2.5.1.36-RXN		molecular_function											owl:Class	
GO:0042811	biolink:NamedThing	pheromone biosynthetic process	The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.	got7fsn_ti	pheromone biosynthesis|pheromone formation|pheromone anabolism|pheromone synthesis													biological_process											owl:Class	
GO:0042030	biolink:NamedThing	ATPase inhibitor activity	Binds to and stops, prevents or reduces an ATP hydrolysis activity.	got7fsn_ti	adenosinetriphosphatase inhibitor	https://github.com/geneontology/go-ontology/issues/20955												molecular_function											owl:Class	
GO:0140678	biolink:NamedThing	molecular function inhibitor activity	A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21782					pg	2021-07-07T07:24:32Z						molecular_function											owl:Class	
GO:0048749	biolink:NamedThing	compound eye development	The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.	got7fsn_ti	insect-type retina development										GO:0007456			biological_process											owl:Class	
GO:1990688	biolink:NamedThing	Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.	got7fsn_ti	Golgi vesicle fusion with ER-Golgi intermediate compartment membrane|Golgi vesicle fusion with ERGIC membrane						bhm	2015-03-12T09:34:21Z						biological_process											owl:Class	
GO:1990668	biolink:NamedThing	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles.	got7fsn_ti	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment membrane|vesicle fusion with ER-Golgi intermediate compartment membrane|vesicle fusion with ER-Golgi intermediate compartment (ERGIC) membrane|vesicle fusion with ERGIC membrane						bhm	2015-03-02T11:17:32Z						biological_process											owl:Class	
GO:0062051	biolink:NamedThing	lipopolysaccharide transport system	A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner.	got7fsn_ti							dph	2018-06-04T18:44:40Z						cellular_component											owl:Class	
GO:0035226	biolink:NamedThing	glutamate-cysteine ligase catalytic subunit binding	Binding to the catalytic subunit of glutamate-cysteine ligase.	got7fsn_ti														molecular_function											owl:Class	
GO:0043847	biolink:NamedThing	DNA polymerase III, clamp loader chi/psi subcomplex	A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III clamp loader complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB).	got7fsn_ti	DNA polymerase III, DnaX complex, chi/psi subcomplex													cellular_component											owl:Class	
GO:0001171	biolink:NamedThing	reverse transcription	A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis.	got7fsn_ti							krc	2011-03-14T03:51:08Z				Wikipedia:Reverse_transcription		biological_process											owl:Class	
GO:0006278	biolink:NamedThing	RNA-dependent DNA biosynthetic process	A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.	got7fsn_ti														biological_process											owl:Class	
GO:0072504	biolink:NamedThing	cellular trivalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of trivalent cations at the level of a cell.	got7fsn_ti					Note that this term was split from 'cellular di-, tri-valent inorganic cation homeostasis ; GO:0030005' (sibling term 'cellular divalent inorganic cation homeostasis' ; GO:0072503').		mah	2010-12-16T01:26:43Z						biological_process											owl:Class	
GO:0030003	biolink:NamedThing	cellular cation homeostasis	Any process involved in the maintenance of an internal steady state of cations at the level of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0150051	biolink:NamedThing	postsynaptic Golgi apparatus	The network of the Golgi apparatus structures located within the postsynapse.	got7fsn_ti	Golgi outpost						bc	2018-05-08T15:42:56Z						cellular_component											owl:Class	
GO:0005794	biolink:NamedThing	Golgi apparatus	A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.	got7fsn_ti	Golgi|Golgi ribbon|Golgi complex				Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.							Wikipedia:Golgi_apparatus|NIF_Subcellular:sao451912436		cellular_component											owl:Class	
GO:0015271	biolink:NamedThing	outward rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.	got7fsn_ti														molecular_function											owl:Class	
GO:0018817	biolink:NamedThing	2-oxo-hept-3-ene-1,7-dioate hydratase activity	Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate.	got7fsn_ti	HpaH|2-oxo-hepta-3-ene-1,7-dioate hydratase activity|2-oxo-hepta-3-ene-1,7-dioic acid hydratase activity											MetaCyc:HYDROXYHEPTA-DIENEDIOATE-HYDROXY-RXN|RHEA:42072|UM-BBD_reactionID:r0369		molecular_function											owl:Class	
GO:0033238	biolink:NamedThing	regulation of cellular amine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.	got7fsn_ti	regulation of amine metabolism													biological_process											owl:Class	
GO:0010945	biolink:NamedThing	CoA pyrophosphatase activity	Catalysis of the reaction: coenzyme A or its derivatives + H2O = 3',5'-ADP + 4'-phosphopantetheine.	got7fsn_ti	conezyme A pyrophosphatase activity						tb	2009-04-22T02:06:40Z				Reactome:R-HSA-6810474|Reactome:R-HSA-6809354		molecular_function											owl:Class	
GO:0047763	biolink:NamedThing	caffeate O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.	got7fsn_ti	S-adenosyl-L-methionine:caffeic acid-O-methyltransferase activity|S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase activity|caffeate 3-O-methyltransferase activity|caffeate methyltransferase activity											RHEA:20225|MetaCyc:RXN-1104|EC:2.1.1.68		molecular_function											owl:Class	
GO:0034904	biolink:NamedThing	5-chloro-2-oxopent-4-enoate hydratase activity	Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate.	got7fsn_ti												UM-BBD_reactionID:r1436		molecular_function											owl:Class	
GO:0072296	biolink:NamedThing	specification of metanephric loop of Henle identity	The process in which the loop of Henle of the metanephric nephron acquires its identity.	got7fsn_ti	specification of metanephric intermediate tubule identity						mah	2010-04-09T04:08:05Z						biological_process											owl:Class	
GO:0017130	biolink:NamedThing	poly(C) RNA binding	Binding to a sequence of cytosine residues in an RNA molecule.	got7fsn_ti	poly(rC) binding|poly(C) binding													molecular_function											owl:Class	
GO:0004158	biolink:NamedThing	dihydroorotate oxidase activity	Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate.	got7fsn_ti	(S)-dihydroorotate:oxygen oxidoreductase activity|4,5-L-dihydroorotate:oxygen oxidoreductase activity											RHEA:15441		molecular_function											owl:Class	
GO:0033563	biolink:NamedThing	dorsal/ventral axon guidance	The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.	got7fsn_ti	dorsal/ventral axon pathfinding|dorsal-ventral axon guidance|dorsoventral axon guidance													biological_process											owl:Class	
GO:0090584	biolink:NamedThing	protein-phosphocysteine-galactitol-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0140549	biolink:NamedThing	spore inner membrane	The membrane surrounding the spore core (endospore core) that separates it from its external environment.	got7fsn_ti	spore membrane	https://github.com/geneontology/go-ontology/issues/20359					pg	2020-11-12T10:00:15Z						cellular_component											owl:Class	
GO:0080027	biolink:NamedThing	response to herbivore	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore.	got7fsn_ti														biological_process											owl:Class	
GO:0007504	biolink:NamedThing	larval fat body development	The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life.	got7fsn_ti														biological_process											owl:Class	
GO:0031882	biolink:NamedThing	type 5 somatostatin receptor binding	Binding to a type 5 somatostatin receptor.	got7fsn_ti	type 5 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0031877	biolink:NamedThing	somatostatin receptor binding	Binding to a somatostatin receptor.	got7fsn_ti	somatostatin receptor ligand													molecular_function											owl:Class	
GO:0019445	biolink:NamedThing	tyrosine catabolic process to fumarate	The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate.	got7fsn_ti	tyrosine breakdown to fumarate|tyrosine degradation to fumarate											MetaCyc:TYRFUMCAT-PWY		biological_process											owl:Class	
GO:0030135	biolink:NamedThing	coated vesicle	Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.	got7fsn_ti											GO:0005909	NIF_Subcellular:sao1985096626		cellular_component											owl:Class	
GO:0046151	biolink:NamedThing	eye pigment catabolic process	The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.	got7fsn_ti	eye pigment catabolism|eye pigment degradation|eye pigment breakdown													biological_process											owl:Class	
GO:0061315	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation	The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of cardiac muscle cell proliferation						dph	2010-09-24T08:53:58Z						biological_process											owl:Class	
GO:0102984	biolink:NamedThing	sulfoacetaldehyde dehydrogenase activity	Catalysis of the reaction: sulfonatoacetaldehyde + H2O + NAD <=> sulfonatoacetate + NADH + 2 H+.	got7fsn_ti												MetaCyc:RXN-9592|RHEA:25637|EC:1.2.1.73		molecular_function											owl:Class	
GO:0005922	biolink:NamedThing	connexin complex	An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction.	got7fsn_ti	connexon complex|connexon											NIF_Subcellular:sao445019788		cellular_component											owl:Class	
GO:0010102	biolink:NamedThing	lateral root morphogenesis	The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.	got7fsn_ti														biological_process											owl:Class	
GO:0048931	biolink:NamedThing	posterior lateral line nerve glial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0048895	biolink:NamedThing	lateral line nerve glial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0000485	biolink:NamedThing	cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0000483	biolink:NamedThing	endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species.	got7fsn_ti														biological_process											owl:Class	
GO:0052856	biolink:NamedThing	NADHX epimerase activity	Catalysis of the reaction: (R)-NADHX = (S)-NADHX.	got7fsn_ti												RHEA:32215|EC:5.1.99.6		molecular_function											owl:Class	
GO:0035943	biolink:NamedThing	estrone secretion	The regulated release of estrone into the circulatory system.	got7fsn_ti	3-hydroxy-1,3,5(10)-estratrien-17-one secretion|folliculin secretion						bf	2011-07-25T02:18:40Z						biological_process											owl:Class	
GO:0030748	biolink:NamedThing	amine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine.	got7fsn_ti	tryptamine methyltransferase|S-adenosyl-L-methionine:amine N-methyltransferase activity|tryptamine N-methyltransferase activity|arylamine N-methyltransferase activity|nicotine N-methyltransferase activity											MetaCyc:AMINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.49		molecular_function											owl:Class	
GO:0018240	biolink:NamedThing	protein S-linked glycosylation via cysteine	The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine.	got7fsn_ti	protein amino acid S-linked glycosylation via cysteine											RESID:AA0152		biological_process											owl:Class	
GO:0051692	biolink:NamedThing	cellular oligosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.	got7fsn_ti	cellular oligosaccharide breakdown|cellular oligosaccharide degradation|cellular oligosaccharide catabolism													biological_process											owl:Class	
GO:0051691	biolink:NamedThing	cellular oligosaccharide metabolic process	The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.	got7fsn_ti	cellular oligosaccharide metabolism													biological_process											owl:Class	
GO:0043905	biolink:NamedThing	Ser-tRNA(Thr) hydrolase activity	Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr).	got7fsn_ti	Ser-tRNAThr hydrolase activity											EC:3.1.1.-		molecular_function											owl:Class	
GO:0097019	biolink:NamedThing	neurotransmitter receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors.	got7fsn_ti	neurotransmitter receptor catabolism|neurotransmitter receptor breakdown|neurotransmitter receptor degradation						pr	2011-03-23T04:16:11Z						biological_process											owl:Class	
GO:0032454	biolink:NamedThing	histone H3-methyl-lysine-9 demethylase activity	Catalysis of the removal of a methyl group from a modified lysine residue at position 9 of the histone H3 protein.	got7fsn_ti	H3K49 demethylase activity|histone demethylase activity (H3-K9 specific)	https://github.com/geneontology/go-ontology/issues/21089										Reactome:R-HSA-9011985|Reactome:R-HSA-9011949|Reactome:R-HSA-997263		molecular_function											owl:Class	
GO:0005586	biolink:NamedThing	collagen type III trimer	A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0033593	biolink:NamedThing	BRCA2-MAGE-D1 complex	A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth.	got7fsn_ti														cellular_component											owl:Class	
GO:0090538	biolink:NamedThing	peptide pheromone secretion	The regulated release of a peptide pheromone from a cell.	got7fsn_ti							tb	2013-02-11T15:38:29Z						biological_process											owl:Class	
GO:0030920	biolink:NamedThing	peptidyl-serine acetylation	The acetylation of peptidyl-serine.	got7fsn_ti														biological_process											owl:Class	
GO:0043652	biolink:NamedThing	engulfment of apoptotic cell	The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.	got7fsn_ti	engulfment of cell corpse|engulfment of apoptotic cell corpse				This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.									biological_process											owl:Class	
GO:0006911	biolink:NamedThing	phagocytosis, engulfment	The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.	got7fsn_ti	phagosome biosynthesis|phagosome formation													biological_process											owl:Class	
GO:0018226	biolink:NamedThing	peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.	got7fsn_ti	peptidyl-S-farnesyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-farnesyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-farnesyl-L-cysteine formation from peptidyl-cysteine											RESID:AA0102		biological_process											owl:Class	
GO:0005295	biolink:NamedThing	neutral amino acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral amino acid(out) + Na+(out) = neutral amino acid(in) + Na+(in).	got7fsn_ti	neutral amino acid-sodium cotransporter|sodium/neutral amino acid transporter										GO:0005282			molecular_function											owl:Class	
GO:0046682	biolink:NamedThing	response to cyclodiene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring.	got7fsn_ti	cyclodiene susceptibility/resistance|cyclodiene resistance													biological_process											owl:Class	
GO:0017085	biolink:NamedThing	response to insecticide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.	got7fsn_ti	insecticide susceptibility/resistance|insecticide resistance													biological_process											owl:Class	
GO:0051132	biolink:NamedThing	NK T cell activation	The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti	NKT cell activation|NK T-lymphocyte activation|NK T lymphocyte activation|natural T cell activation|NT cell activation|NK T-cell activation|natural killer T cell activation				Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repetoire of variable region gene segments.									biological_process											owl:Class	
GO:0035729	biolink:NamedThing	cellular response to hepatocyte growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.	got7fsn_ti	cellular response to HGF stimulus						bf	2011-03-10T03:04:19Z						biological_process											owl:Class	
GO:0035728	biolink:NamedThing	response to hepatocyte growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.	got7fsn_ti	response to HGF stimulus|response to hepatocyte growth factor stimulus						bf	2011-03-10T03:02:47Z						biological_process											owl:Class	
GO:0050574	biolink:NamedThing	2-(R)-hydroxypropyl-CoM dehydrogenase activity	Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH.	got7fsn_ti	2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase activity|2-[2-(R)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity											RHEA:13249|EC:1.1.1.268|MetaCyc:1.1.1.268-RXN|KEGG_REACTION:R05689|UM-BBD_reactionID:r0852		molecular_function											owl:Class	
GO:0043716	biolink:NamedThing	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity	Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene.	got7fsn_ti	2-hydroxy-3-keto-5-methylthio-phosphopentene phosphatase activity|HK-MTPenyl-1-P phosphatase activity											MetaCyc:R83-RXN|RHEA:14481|KEGG_REACTION:R07394		molecular_function											owl:Class	
GO:0004181	biolink:NamedThing	metallocarboxypeptidase activity	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681										MetaCyc:CARBOXYPEPTIDASE-H-RXN|Reactome:R-HSA-9023163|MetaCyc:GLY-X-CARBOXYPEPTIDASE-RXN|EC:3.4.17.6|MetaCyc:LYSINEARGININE-CARBOXYPEPTIDASE-RXN|EC:3.4.17.4|Reactome:R-HSA-2028294|EC:3.4.17.21|MetaCyc:ALANINE-CARBOXYPEPTIDASE-RXN|MetaCyc:CARBOXYPEPTIDASE-B-RXN|EC:3.4.17.22|EC:3.4.17.-|EC:3.4.17.10|Reactome:R-HSA-8955712|EC:3.4.17.1|MetaCyc:CARBOXYPEPTIDASE-A-RXN|MetaCyc:3.4.17.17-RXN|Reactome:R-HSA-2022378|Reactome:R-HSA-9023159|MetaCyc:3.4.17.22-RXN|EC:3.4.17.17|Reactome:R-HSA-8852809|EC:3.4.17.3|Reactome:R-HSA-8866105|Reactome:R-HSA-2022379|EC:3.4.17.2		molecular_function											owl:Class	
GO:0004180	biolink:NamedThing	carboxypeptidase activity	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681										MetaCyc:3.4.17.11-RXN|EC:3.4.17.11|Reactome:R-HSA-1247910|RHEA:28783		molecular_function											owl:Class	
GO:0008401	biolink:NamedThing	retinoic acid 4-hydroxylase activity	Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.	got7fsn_ti	cytochrome P450 CYP261											Reactome:R-HSA-5602050|Reactome:R-HSA-211923|Reactome:R-HSA-211874|Reactome:R-HSA-212007|Reactome:R-HSA-5362525|Reactome:R-HSA-5602063		molecular_function											owl:Class	
GO:0090671	biolink:NamedThing	telomerase RNA localization to Cajal body	A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.	got7fsn_ti							tb	2015-12-17T14:06:21Z						biological_process											owl:Class	
GO:0010147	biolink:NamedThing	fructan catabolic process	The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues.	got7fsn_ti	fructan degradation|fructan catabolism|fructan breakdown|levan catabolism|levan catabolic process											MetaCyc:PWY-862		biological_process											owl:Class	
GO:0070093	biolink:NamedThing	negative regulation of glucagon secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.	got7fsn_ti	down regulation of glucagon secretion|inhibition of glucagon secretion|downregulation of glucagon secretion|down-regulation of glucagon secretion													biological_process											owl:Class	
GO:0045157	biolink:NamedThing	electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity	Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis.	got7fsn_ti	cytochrome													molecular_function											owl:Class	
GO:0060073	biolink:NamedThing	micturition	The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.	got7fsn_ti	urination|urine voiding											Wikipedia:Urination		biological_process											owl:Class	
GO:0002017	biolink:NamedThing	regulation of blood volume by renal aldosterone	The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume.	got7fsn_ti	renal regulation of blood volume by aldosterone|aldosterone mediated control of body fluids|aldosterone mediated regulation of blood volume													biological_process											owl:Class	
GO:0001977	biolink:NamedThing	renal system process involved in regulation of blood volume	A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.	got7fsn_ti	renal blood volume control of blood pressure|renal regulation of blood volume													biological_process											owl:Class	
GO:0002384	biolink:NamedThing	hepatic immune response	An immune response taking place in the liver.	got7fsn_ti														biological_process											owl:Class	
GO:0002251	biolink:NamedThing	organ or tissue specific immune response	An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues.	got7fsn_ti	immune response in organ or tissue													biological_process											owl:Class	
GO:0004513	biolink:NamedThing	neolactotetraosylceramide alpha-2,3-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide.	got7fsn_ti	cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase activity|SAT-3|CMP-N-acetylneuraminate:neolactotetraosylceramide alpha-2,3-sialyltransferase activity|sialyltransferase 3											EC:2.4.99.10|MetaCyc:2.4.99.10-RXN|RHEA:18913		molecular_function											owl:Class	
GO:0010429	biolink:NamedThing	methyl-CpNpN binding	Binding to a methylated cytosine/unspecified/unspecified trinucleotide.	got7fsn_ti														molecular_function											owl:Class	
GO:0000166	biolink:NamedThing	nucleotide binding	Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.	got7fsn_ti														molecular_function											owl:Class	
GO:0016886	biolink:NamedThing	ligase activity, forming phosphoric ester bonds	Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti												EC:6.5.-.-		molecular_function											owl:Class	
GO:0016874	biolink:NamedThing	ligase activity	Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.	got7fsn_ti	synthetase activity	https://github.com/geneontology/go-ontology/issues/19380										EC:6.-.-.-		molecular_function											owl:Class	
GO:0001064	biolink:NamedThing	single subunit type RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti	T3/T7 type RNA polymerase activity						krc	2010-10-19T03:47:56Z						molecular_function											owl:Class	
GO:0003899	biolink:NamedThing	DNA-directed 5'-3' RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti	DNA-directed RNA polymerase III activity|DNA-dependent ribonucleate nucleotidyltransferase activity|transcriptase|RNA polymerase II activity|DNA-dependent RNA nucleotidyltransferase activity|DNA-directed RNA polymerase activity|DNA-dependent RNA polymerase activity|C RNA formation factors|DNA-directed RNA polymerase I activity|deoxyribonucleic acid-dependent ribonucleic acid polymerase activity|RNA polymerase III activity|nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity|DNA-directed RNA polymerase II activity|RNA polymerase I activity|C ribonucleic acid formation factors|RNA nucleotidyltransferase (DNA-directed) activity										GO:0000129	Reactome:R-HSA-174425|Reactome:R-HSA-75873|Reactome:R-HSA-167136|Reactome:R-HSA-6781824|Reactome:R-HSA-167115|Reactome:R-HSA-167117|Reactome:R-HSA-75869|EC:2.7.7.6|Reactome:R-HSA-5601926|Reactome:R-HSA-203901|Reactome:R-HSA-9697084|Reactome:R-HSA-111264|Reactome:R-HSA-9670149|Reactome:R-HSA-427366|MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN|Reactome:R-HSA-167113|Reactome:R-HSA-76576|Reactome:R-HSA-9697085|Reactome:R-HSA-68913|Reactome:R-HSA-74986|Reactome:R-HSA-75850|Reactome:R-HSA-167121		molecular_function											owl:Class	
GO:0061040	biolink:NamedThing	female gonad morphogenesis	The process in which a female gonad is generated and organized.	got7fsn_ti	ovary morphogenesis						dph	2010-02-22T11:29:28Z						biological_process											owl:Class	
GO:0035262	biolink:NamedThing	gonad morphogenesis	The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.	got7fsn_ti														biological_process											owl:Class	
GO:0071693	biolink:NamedThing	protein transport within extracellular region	The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore.	got7fsn_ti							mah	2010-02-25T04:02:35Z						biological_process											owl:Class	
GO:0001742	biolink:NamedThing	oenocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.	got7fsn_ti	oenocyte cell differentiation													biological_process											owl:Class	
GO:0098755	biolink:NamedThing	maintenance of seed dormancy by absisic acid	The process by which seed dormancy is maintained by the presence of absisic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0010231	biolink:NamedThing	maintenance of seed dormancy	Any process that maintains a seed in a dormant state.	got7fsn_ti														biological_process											owl:Class	
GO:0031120	biolink:NamedThing	snRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0050514	biolink:NamedThing	homospermidine synthase (spermidine-specific) activity	Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine.	got7fsn_ti	spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming)											MetaCyc:2.5.1.45-RXN|RHEA:11236|EC:2.5.1.45		molecular_function											owl:Class	
GO:0102928	biolink:NamedThing	beta-solanine rhamnosyltransferase activity	Catalysis of the reaction: beta-solanine + UDP-L-rhamnose = solanine + UDP.	got7fsn_ti												MetaCyc:RXN-8884		molecular_function											owl:Class	
GO:0019148	biolink:NamedThing	D-cysteine desulfhydrase activity	Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate.	got7fsn_ti	D-cysteine sulfide-lyase (deaminating)|D-cysteine sulfide-lyase (deaminating; pyruvate-forming)|D-cysteine lyase activity											MetaCyc:DCYSDESULF-RXN|RHEA:11268|EC:4.4.1.15		molecular_function											owl:Class	
GO:0018361	biolink:NamedThing	peptidyl-glutamine 2-methylation	The methylation of glutamine to form 2-methyl-L-glutamine.	got7fsn_ti												RESID:AA0273		biological_process											owl:Class	
GO:0047996	biolink:NamedThing	hydroxyphytanate oxidase activity	Catalysis of the reaction: (2S)-2-hydroxyphytanate + O(2) = 2-oxophytanate + H(2)O(2).	got7fsn_ti	L-2-hydroxyphytanate:oxygen 2-oxidoreductase											KEGG_REACTION:R07151|MetaCyc:HYDROXYPHYTANATE-OXIDASE-RXN|EC:1.1.3.27|RHEA:21680		molecular_function											owl:Class	
GO:0002136	biolink:NamedThing	tRNA wobble base lysidine biosynthesis	The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.	got7fsn_ti					Exclusively located at the anticodon wobble position (i.e., position 34) of eubacterial and some organellar tRNAIle2. This modification converts the codon specificity from AUG to AUA, and it also converts the aminoacylation specificity of the tRNA from methionine to isoleucine. Requires ATP.									biological_process											owl:Class	
GO:0002101	biolink:NamedThing	tRNA wobble cytosine modification	The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified.	got7fsn_ti														biological_process											owl:Class	
GO:0035188	biolink:NamedThing	hatching	The emergence of an immature organism from a protective structure.	got7fsn_ti														biological_process											owl:Class	
GO:0071684	biolink:NamedThing	organism emergence from protective structure	The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.	got7fsn_ti							mah	2010-02-19T04:23:55Z						biological_process											owl:Class	
GO:0035447	biolink:NamedThing	mycothiol synthase activity	Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol.	got7fsn_ti	acetyl-CoA:Cys-GlcN-Ins acetyltransferase						bf	2010-04-14T11:40:26Z				MetaCyc:MONOMER-9684		molecular_function											owl:Class	
GO:0140221	biolink:NamedThing	pathogen-containing vacuole membrane	Host-derived membrane of a pathogen-containing vacuole.	got7fsn_ti	pathogen inclusion membrane|pathogen-containing compartment membrane	https://github.com/geneontology/go-ontology/issues/15580					pg	2018-04-20T06:18:25Z						cellular_component											owl:Class	
GO:0036392	biolink:NamedThing	chemokine (C-C motif) ligand 20 production	The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	C-C motif chemokine 20 production|CCL-20 production|CCL20 production						bf	2013-06-17T14:42:07Z						biological_process											owl:Class	
GO:0046315	biolink:NamedThing	phosphocreatine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.	got7fsn_ti	phosphocreatine breakdown|phosphocreatine catabolism|phosphocreatine degradation													biological_process											owl:Class	
GO:0046406	biolink:NamedThing	magnesium protoporphyrin IX methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H(+) + magnesium protoporphyrin IX 13-monomethyl ester.	got7fsn_ti	(-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX methyltransferase activity|S-adenosyl-L-methionine:magnesium-protoporphyrin O-methyltransferase activity|S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase activity|magnesium-protoporphyrin O-methyltransferase activity|S-adenosylmethionine-magnesium protoporphyrin methyltransferase activity|S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase activity|Mg-protoporphyrin IX methyltransferase activity|S-adenosylmethioninemagnesium protoporphyrin methyltransferase activity											RHEA:17809|MetaCyc:RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN|KEGG_REACTION:R04237|EC:2.1.1.11		molecular_function											owl:Class	
GO:0046701	biolink:NamedThing	insecticide catabolic process	The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects.	got7fsn_ti	insecticide catabolism|insecticide breakdown|insecticide degradation													biological_process											owl:Class	
GO:0035801	biolink:NamedThing	adrenal cortex development	The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).	got7fsn_ti	adrenal gland cortex development						bf	2011-04-18T10:25:39Z						biological_process											owl:Class	
GO:0097137	biolink:NamedThing	BAD-BCL-xl complex	A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:36:06Z						cellular_component											owl:Class	
GO:0051932	biolink:NamedThing	synaptic transmission, GABAergic	The vesicular release of  gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	got7fsn_ti	GABAergic synaptic transmission|synaptic transmission, gamma-aminobutyric acid mediated|synaptic transmission, gamma-aminobutyric acid-ergic|synaptic transmission, GABA mediated													biological_process											owl:Class	
GO:0018339	biolink:NamedThing	peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid	The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12.	got7fsn_ti	peptidyl-L-beta-methylthioaspartic acid anabolism from peptidyl-aspartic acid|peptidyl-L-beta-methylthioaspartic acid synthesis from peptidyl-aspartic acid|peptidyl-aspartic acid methylthiolation|peptidyl-L-beta-methylthioaspartic acid formation from peptidyl-aspartic acid											RESID:AA0232		biological_process											owl:Class	
GO:0031943	biolink:NamedThing	regulation of glucocorticoid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.	got7fsn_ti	regulation of glucocorticoid metabolism													biological_process											owl:Class	
GO:0048497	biolink:NamedThing	maintenance of floral organ identity	The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0047083	biolink:NamedThing	5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity	Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate.	got7fsn_ti	trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)|coumaroylquinate(coumaroylshikimate) 3'-monooxygenase activity|5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase activity											EC:1.14.14.96|MetaCyc:1.14.13.36-RXN|RHEA:16265		molecular_function											owl:Class	
GO:0036320	biolink:NamedThing	mating-type P-factor pheromone receptor activity	Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus.	got7fsn_ti	P-factor mating pheromone receptor activity|P-factor receptor activity						bf	2012-08-30T16:55:30Z						molecular_function											owl:Class	
GO:0071517	biolink:NamedThing	maintenance of imprinting at mating-type locus	Any process involved in preserving the structure of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.	got7fsn_ti	mating type determination, maintenance of imprinting						mah	2010-01-06T01:17:05Z						biological_process											owl:Class	
GO:0072283	biolink:NamedThing	metanephric renal vesicle morphogenesis	The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.	got7fsn_ti							mah	2010-04-01T03:28:00Z						biological_process											owl:Class	
GO:0072077	biolink:NamedThing	renal vesicle morphogenesis	The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.	got7fsn_ti							mah	2010-02-01T02:21:06Z						biological_process											owl:Class	
GO:0047596	biolink:NamedThing	6-methylsalicylate decarboxylase activity	Catalysis of the reaction: 6-methylsalicylate + H(+) = 3-cresol + CO(2).	got7fsn_ti	6-MSA decarboxylase activity|6-methylsalicylate carboxy-lyase (3-cresol-forming)|6-methylsalicylic acid (2,6-cresotic acid) decarboxylase activity|6-methylsalicylate carboxy-lyase activity											RHEA:23112|EC:4.1.1.52|MetaCyc:6-METHYLSALICYLATE-DECARBOXYLASE-RXN|KEGG_REACTION:R03567		molecular_function											owl:Class	
GO:0034703	biolink:NamedThing	cation channel complex	An ion channel complex through which cations pass.	got7fsn_ti														cellular_component											owl:Class	
GO:0097436	biolink:NamedThing	entry into dormancy	The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.	got7fsn_ti	induction of dormancy						pr	2012-12-05T14:55:49Z						biological_process											owl:Class	
GO:0102555	biolink:NamedThing	octanoyl transferase activity (acting on glycine-cleavage complex H protein)	Catalysis of the reaction: [glycine cleavage system lipoyl-carrier protein]-L-lysine + octanoyl-ACP = H+ + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein].	got7fsn_ti												EC:2.3.1.181|MetaCyc:RXN-14966|RHEA:17665		molecular_function											owl:Class	
GO:0016415	biolink:NamedThing	octanoyltransferase activity	Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule.	got7fsn_ti												EC:2.3.1.181		molecular_function											owl:Class	
GO:0014834	biolink:NamedThing	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells.  Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells.	got7fsn_ti	satellite cell compartment self-renewal involved in skeletal muscle regeneration|satellite cell population maintenance|satellite cell self-renewal													biological_process											owl:Class	
GO:0098727	biolink:NamedThing	maintenance of cell number	Any process by which the numbers of cells of a particular type or in a tissue are maintained.	got7fsn_ti														biological_process											owl:Class	
GO:0004589	biolink:NamedThing	orotate reductase (NADH) activity	Catalysis of the reaction: (S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate.	got7fsn_ti	(S)-dihydroorotate:NAD+ oxidoreductase activity											RHEA:13513|KEGG_REACTION:R01869|MetaCyc:OROTATE-REDUCTASE-NADH-RXN|EC:1.3.1.14		molecular_function											owl:Class	
GO:0019607	biolink:NamedThing	phenylethylamine catabolic process	The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.	got7fsn_ti	phenylethylamine degradation|phenylethylamine catabolism|phenylethylamine breakdown											MetaCyc:2PHENDEG-PWY		biological_process											owl:Class	
GO:0048877	biolink:NamedThing	homeostasis of number of retina cells	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina.	got7fsn_ti														biological_process											owl:Class	
GO:0051239	biolink:NamedThing	regulation of multicellular organismal process	Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.	got7fsn_ti														biological_process											owl:Class	
GO:0071075	biolink:NamedThing	CUGBP1-eIF2 complex	A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation.	got7fsn_ti							mah	2009-11-06T01:43:30Z						cellular_component											owl:Class	
GO:0031719	biolink:NamedThing	type 2 cannabinoid receptor binding	Binding to a type 2 cannabinoid receptor.	got7fsn_ti	type 2 cannabinoid receptor ligand													molecular_function											owl:Class	
GO:0031717	biolink:NamedThing	cannabinoid receptor binding	Binding to a cannabinoid receptor.	got7fsn_ti	cannabinoid receptor ligand													molecular_function											owl:Class	
GO:0060024	biolink:NamedThing	rhythmic synaptic transmission	Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.	got7fsn_ti														biological_process											owl:Class	
GO:0050804	biolink:NamedThing	modulation of chemical synaptic transmission	Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.  Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.	got7fsn_ti	regulation of synaptic transmission|modulation of synaptic transmission|regulation of chemical synaptic transmission													biological_process											owl:Class	
GO:0070257	biolink:NamedThing	positive regulation of mucus secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.	got7fsn_ti	positive regulation of mucus production													biological_process											owl:Class	
GO:0098855	biolink:NamedThing	HCN channel complex	A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart.	got7fsn_ti	HCN1 channel complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel complex|potassium/sodium hyperpolarization-activated channel 3 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 2 complex|HCN2 channel complex|HCN4 channel complex|HCN3 channel complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 4 complex|K/Na hyperpolarization-activated channel 3 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 tetramer|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel complex										GO:1990746|GO:1990759			cellular_component											owl:Class	
GO:0097087	biolink:NamedThing	interleukin-17A production	The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-17A biosynthetic process|IL-17A production						bc	2011-06-23T11:31:10Z			GO:0150154			biological_process											owl:Class	
GO:0097352	biolink:NamedThing	autophagosome maturation	Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.	got7fsn_ti	autophagic vacuole fusion|autophagosome fusion|autophagic vacuole maturation						pr	2012-06-28T03:12:18Z			GO:0000046			biological_process											owl:Class	
GO:0061779	biolink:NamedThing	Tapasin-ERp57 complex	Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.	got7fsn_ti							dph	2016-08-05T12:12:08Z						cellular_component											owl:Class	
GO:0009383	biolink:NamedThing	rRNA (cytosine-C5-)-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.	got7fsn_ti	rRNA m5C967 methyltransferase activity|rRNA (cytosine-C5-967)-methyltransferase activity											Reactome:R-HSA-6793057|Reactome:R-HSA-6790944		molecular_function											owl:Class	
GO:0003028	biolink:NamedThing	regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling	The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.	got7fsn_ti	aortic body chemoreceptor regulation of systemic arterial blood pressure|aortic body chemoreceptor response to lowering of systemic arterial blood pressure|regulation of systemic arterial blood pressure by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0001979	biolink:NamedThing	regulation of systemic arterial blood pressure by chemoreceptor signaling	The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.	got7fsn_ti	chemoreceptor control of blood pressure|regulation of systemic arterial blood pressure by chemoreceptor signalling|chemoreceptor regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0010376	biolink:NamedThing	stomatal complex formation	The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells.	got7fsn_ti														biological_process											owl:Class	
GO:0009020	biolink:NamedThing	tRNA (guanosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine.	got7fsn_ti	tRNA guanosine 2'-methyltransferase activity|transfer ribonucleate guanosine 2'-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase activity|tRNA (Gm18) methyltransferase activity|S-adenosyl-L-methionine:tRNA guanosine-2'-O-methyltransferase activity|tRNA (guanosine 2')-methyltransferase activity|tRNA (Gm18) 2'-O-methyltransferase activity|tRNA guanosine-2'-O-methyltransferase activity											RHEA:20077|MetaCyc:2.1.1.34-RXN|EC:2.1.1.34|Reactome:R-HSA-9024161		molecular_function											owl:Class	
GO:0050247	biolink:NamedThing	raucaffricine beta-glucosidase activity	Catalysis of the reaction: H(2)O + raucaffricine = D-glucose + vomilenine.	got7fsn_ti	raucaffricine beta-D-glucohydrolase activity|raucaffricine b-glucosidase activity|raucaffricine glucosidase activity|raucaffricine beta-D-glucosidase activity											EC:3.2.1.125|RHEA:14557|MetaCyc:RAUCAFFRICINE-BETA-GLUCOSIDASE-RXN|KEGG_REACTION:R03703		molecular_function											owl:Class	
GO:0033608	biolink:NamedThing	formyl-CoA transferase activity	Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.	got7fsn_ti	formyl-coenzyme A transferase activity|formyl-CoA:oxalate CoA-transferase activity|formyl-CoA oxalate CoA-transferase activity											KEGG_REACTION:R07290|EC:2.8.3.16|RHEA:16545|MetaCyc:RXN0-1382		molecular_function											owl:Class	
GO:0005161	biolink:NamedThing	platelet-derived growth factor receptor binding	Binding to a platelet-derived growth factor receptor.	got7fsn_ti	platelet-derived growth factor|PDGFR binding|platelet-derived growth factor receptor ligand|PDGF receptor binding|PDGF													molecular_function											owl:Class	
GO:0061555	biolink:NamedThing	ganglion structural organization	The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	ganglia structural organization						dph	2013-07-10T08:54:39Z						biological_process											owl:Class	
GO:0070633	biolink:NamedThing	transepithelial transport	The directed movement of a substance from one side of an epithelium to the other.	got7fsn_ti							mah	2009-05-06T03:31:02Z						biological_process											owl:Class	
GO:0019414	biolink:NamedThing	aerobic respiration, using sulfur or sulfate as electron donor	An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized.	got7fsn_ti	aerobic respiration, using sulphur or sulphate as electron donor													biological_process											owl:Class	
GO:0140059	biolink:NamedThing	dendrite arborization	The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches.	got7fsn_ti							pg	2017-07-12T15:12:07Z						biological_process											owl:Class	
GO:0048813	biolink:NamedThing	dendrite morphogenesis	The process in which the anatomical structures of a dendrite are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0034800	biolink:NamedThing	trinitrophenol dihydride denitratase activity	Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.	got7fsn_ti	TNP dihydride denitratase activity|2,4,6-trinitrophenol dihydride denitratase activity											EC:1.7.99.-|UM-BBD_reactionID:r1067		molecular_function											owl:Class	
GO:0150057	biolink:NamedThing	amylin receptor complex 2	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM).	got7fsn_ti	AMY2 complex						bc	2018-06-21T10:51:35Z						cellular_component											owl:Class	
GO:1903440	biolink:NamedThing	amylin receptor complex	A protein complex which is capable of amylin receptor activity.	got7fsn_ti							pr	2014-09-16T13:25:20Z						cellular_component											owl:Class	
GO:0004699	biolink:NamedThing	calcium-independent protein kinase C activity	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol but not calcium.	got7fsn_ti	calcium-independent PKC activity|novel protein kinase C activity											Reactome:R-HSA-5607740		molecular_function											owl:Class	
GO:0004697	biolink:NamedThing	protein kinase C activity	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.	got7fsn_ti	PKC activity|PKCgamma|nPKCtheta|cPKC|nPKCepsilon|Pkc1p|cPKCbeta|diacylglycerol-activated phospholipid-dependent protein kinase C activity|PKCbeta|STK24|PKC|cPKCgamma|PKCdelta|nPKCeta|nPKCdelta|PKCzeta|PKCepsilon|nPKC|ATP:protein phosphotransferase (diacylglycerol-dependent) activity|protein kinase Cepsilon activity|cPKCalpha|PKCalpha|diacylglycerol-activated phospholipid-dependent PKC activity										GO:0004701	Reactome:R-HSA-2179413|Reactome:R-HSA-5218823|Reactome:R-HSA-5623667|Reactome:R-HSA-5229194|Reactome:R-HSA-5671749|Reactome:R-HSA-5138432|Reactome:R-HSA-2730863|Reactome:R-HSA-5218805|Reactome:R-HSA-927889|EC:2.7.11.13|Reactome:R-HSA-9010681|Reactome:R-HSA-193703|Reactome:R-HSA-450533|Reactome:R-HSA-8934446|Reactome:R-HSA-9021357|Reactome:R-HSA-751040|MetaCyc:2.7.11.13-RXN|Reactome:R-HSA-374664|Reactome:R-HSA-909552|Reactome:R-HSA-450550|Reactome:R-HSA-9626817|Reactome:R-HSA-198314|Reactome:R-HSA-1433508|Reactome:R-HSA-9632858|Reactome:R-HSA-74615|Reactome:R-HSA-5625784|Reactome:R-HSA-429698		molecular_function											owl:Class	
GO:0090096	biolink:NamedThing	positive regulation of metanephric cap mesenchymal cell proliferation	Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.	got7fsn_ti							tb	2009-11-13T10:40:32Z						biological_process											owl:Class	
GO:0090184	biolink:NamedThing	positive regulation of kidney development	Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti	positive regulation of nephrogenesis						tb	2009-12-18T10:52:01Z						biological_process											owl:Class	
GO:0010154	biolink:NamedThing	fruit development	The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.	got7fsn_ti														biological_process											owl:Class	
GO:0035237	biolink:NamedThing	corazonin receptor activity	Combining with the neuropeptide corazonin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0000829	biolink:NamedThing	inositol heptakisphosphate kinase activity	Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.	got7fsn_ti												Reactome:R-HSA-1855182|Reactome:R-HSA-1855194|Reactome:R-HSA-1855157		molecular_function											owl:Class	
GO:0006853	biolink:NamedThing	carnitine shuttle	The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine.	got7fsn_ti					See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.							Wikipedia:Carnitine#Role_in_fatty_acid_metabolism		biological_process											owl:Class	
GO:0033227	biolink:NamedThing	dsRNA transport	The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0060893	biolink:NamedThing	limb granular cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti							dph	2009-08-13T01:44:14Z						biological_process											owl:Class	
GO:0097344	biolink:NamedThing	Rix1 complex	A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes.	got7fsn_ti	IPI complex						pr	2012-06-18T01:38:49Z						cellular_component											owl:Class	
GO:0070193	biolink:NamedThing	synaptonemal complex organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.	got7fsn_ti	synaptonemal complex organisation													biological_process											owl:Class	
GO:0052898	biolink:NamedThing	N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2).	got7fsn_ti												RHEA:25864|EC:1.5.3.15		molecular_function											owl:Class	
GO:0045010	biolink:NamedThing	actin nucleation	The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.	got7fsn_ti	actin filament nucleation													biological_process											owl:Class	
GO:0001184	biolink:NamedThing	promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I at a promoter for the nuclear large ribosomal RNA (rRNA) transcript, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.	got7fsn_ti							krc	2011-08-15T04:03:52Z						biological_process											owl:Class	
GO:0001182	biolink:NamedThing	promoter clearance from RNA polymerase I promoter	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.	got7fsn_ti							krc	2011-08-15T03:49:28Z						biological_process											owl:Class	
GO:0047911	biolink:NamedThing	galacturan 1,4-alpha-galacturonidase activity	Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.	got7fsn_ti	poly(1,4-alpha-D-galacturonide) galacturonohydrolase activity|exo-D-galacturonanase activity|exo-D-galacturonase activity|exopoly-D-galacturonase activity|exo-polygalacturonase activity|galacturan alpha-1,4-galacturonidase activity|poly(galacturonate) hydrolase activity|exopolygalacturonase activity											EC:3.2.1.67|RHEA:14117|MetaCyc:GALACTURAN-14-ALPHA-GALACTURONIDASE-RXN		molecular_function											owl:Class	
GO:0032918	biolink:NamedThing	spermidine acetylation	The modification of spermidine by addition of acetyl groups.	got7fsn_ti														biological_process											owl:Class	
GO:0008216	biolink:NamedThing	spermidine metabolic process	The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	got7fsn_ti	spermidine metabolism													biological_process											owl:Class	
GO:1990789	biolink:NamedThing	thyroid gland epithelial cell proliferation	The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population.	got7fsn_ti	Hurthle cell proliferation|thyroid follicular cell proliferation						sl	2015-07-02T18:50:01Z						biological_process											owl:Class	
GO:0031964	biolink:NamedThing	beta-alanyl-histamine hydrolase activity	Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine.	got7fsn_ti	carcinine hydrolase activity													molecular_function											owl:Class	
GO:0097545	biolink:NamedThing	axonemal outer doublet	Part of an axoneme consisting in a doublet microtubule. Nine of these outer doublets form the 9+0 axoneme, while the 9+2 axoneme also contains a central pair. Dynein arms attached to the doublets provide the mechanism of movement of the cilium.	got7fsn_ti	axoneme outer doublet|outer doublet|outer-doublet microtubules						pr	2013-12-12T11:19:29Z						cellular_component											owl:Class	
GO:0044092	biolink:NamedThing	negative regulation of molecular function	Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.	got7fsn_ti							jl	2009-04-21T04:07:27Z						biological_process											owl:Class	
GO:0002750	biolink:NamedThing	antigen processing and presentation following macropinocytosis	Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0038113	biolink:NamedThing	interleukin-9-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-9 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-9-mediated signalling pathway|IL-9-mediated signaling pathway						bf	2012-03-22T10:20:33Z						biological_process											owl:Class	
GO:0098688	biolink:NamedThing	parallel fiber to Purkinje cell synapse	An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.	got7fsn_ti							dos	2017-02-21T18:32:05Z						cellular_component											owl:Class	
GO:0061143	biolink:NamedThing	alveolar primary septum development	The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.	got7fsn_ti							dph	2010-05-25T10:21:27Z						biological_process											owl:Class	
GO:0060428	biolink:NamedThing	lung epithelium development	The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.	got7fsn_ti	pulmonary epithelium development													biological_process											owl:Class	
GO:0048939	biolink:NamedThing	anterior lateral line nerve glial cell development	The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0048937	biolink:NamedThing	lateral line nerve glial cell development	The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:2000294	biolink:NamedThing	positive regulation of defecation	Any process that activates or increases the frequency, rate or extent of defecation.	got7fsn_ti							bf	2010-12-21T09:23:16Z						biological_process											owl:Class	
GO:0060292	biolink:NamedThing	long-term synaptic depression	A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.	got7fsn_ti	LTD|long term depression|long term synaptic depression													biological_process											owl:Class	
GO:0048167	biolink:NamedThing	regulation of synaptic plasticity	A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	got7fsn_ti					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:0009017	biolink:NamedThing	succinylglutamate desuccinylase activity	Catalysis of the reaction: N-succinyl-L-glutamate + H(2)O = L-glutamate + succinate.	got7fsn_ti	AstE|N-succinyl-L-glutamate amidohydrolase activity|N2-succinylglutamate desuccinylase activity|SGDS											MetaCyc:SUCCGLUDESUCC-RXN|KEGG_REACTION:R00411|RHEA:15169|EC:3.5.1.96		molecular_function											owl:Class	
GO:0047664	biolink:NamedThing	aminoimidazolase activity	Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH(3).	got7fsn_ti	4-aminoimidazole hydrolase activity|4-aminoimidazole aminohydrolase activity											EC:3.5.4.8|RHEA:22348|MetaCyc:R13-RXN		molecular_function											owl:Class	
GO:0043153	biolink:NamedThing	entrainment of circadian clock by photoperiod	The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).	got7fsn_ti	photoentrainment of circadian clock													biological_process											owl:Class	
GO:0034664	biolink:NamedThing	Ig heavy chain-bound endoplasmic reticulum chaperone complex	A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.	got7fsn_ti	Ig heavy chain-bound ER chaperone complex|immunoglobulin heavy chain-bound endoplasmic reticulum chaperone complex													cellular_component											owl:Class	
GO:0050207	biolink:NamedThing	plasmanylethanolamine desaturase activity	Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O.	got7fsn_ti	alkylacylglycerophosphoethanolamine desaturase activity|alkylacylglycero-phosphorylethanolamine dehydrogenase activity|plasmenylethanolamine desaturase activity|O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase activity|dehydrogenase, alkyl-acylglycerophosphorylethanolamine|1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity|1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity											RHEA:22956|EC:1.14.19.77|MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN		molecular_function											owl:Class	
GO:0034190	biolink:NamedThing	apolipoprotein receptor binding	Binding to an apolipoprotein receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0018273	biolink:NamedThing	protein-chromophore linkage via peptidyl-N6-retinal-L-lysine	The modification of peptidyl-lysine to form N6-retinal-L-lysine.	got7fsn_ti												RESID:AA0120		biological_process											owl:Class	
GO:0071558	biolink:NamedThing	histone H3-tri/di-methyl-lysine-27 demethylase activity	Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 27 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone H3K27me2 demethylase activity|histone H3K27me3 demethylase activity|histone demethylase activity (H3-K27 specific)						mah	2010-01-15T11:33:17Z				RHEA:60224|EC:1.14.11.68|Reactome:R-HSA-3222593|Reactome:R-HSA-5617431|Reactome:R-HSA-5617887		molecular_function											owl:Class	
GO:0039671	biolink:NamedThing	evasion by virus of host natural killer cell activity	Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells.	got7fsn_ti	evasion by virus of host natural killer cell response|viral immunoevasion of host NK cell|evasion by virus of host NK cell killing|modulation of host NK-cell activity by virus|suppression by virus of host natural killer cell function|protection by virus against host NK cell cytotoxicity						bf	2013-09-25T11:04:53Z						biological_process											owl:Class	
GO:0019228	biolink:NamedThing	neuronal action potential	An action potential that occurs in a neuron.	got7fsn_ti	generation of action potential													biological_process											owl:Class	
GO:0006648	biolink:NamedThing	dihydrosphingosine-1-P pathway	A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase.	got7fsn_ti														biological_process											owl:Class	
GO:0006646	biolink:NamedThing	phosphatidylethanolamine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.	got7fsn_ti	phosphatidylethanolamine formation|phosphatidylethanolamine anabolism|phosphatidylethanolamine synthesis|phosphatidylethanolamine biosynthesis													biological_process											owl:Class	
GO:0072318	biolink:NamedThing	clathrin coat disassembly	The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.	got7fsn_ti	clathrin-coat disassembly|clathrin-coat uncoating|clathrin-coated vesicle uncoating						mah	2010-10-26T12:03:37Z						biological_process											owl:Class	
GO:0072319	biolink:NamedThing	vesicle uncoating	A protein depolymerization process that results in the disassembly of vesicle coat proteins.	got7fsn_ti	vesicle coat disassembly						mah	2010-10-26T12:09:21Z						biological_process											owl:Class	
GO:0047849	biolink:NamedThing	dextransucrase activity	Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1).	got7fsn_ti	sucrose 6-glucosyltransferase activity|sucrose-1,6-alpha-glucan glucosyltransferase activity|sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity|CEP|SGE											EC:2.4.1.5|MetaCyc:DEXTRANSUCRASE-RXN		molecular_function											owl:Class	
GO:0098791	biolink:NamedThing	Golgi apparatus subcompartment	A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus.	got7fsn_ti	Golgi subcompartment													cellular_component											owl:Class	
GO:0002466	biolink:NamedThing	peripheral tolerance induction to self antigen	Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0090114	biolink:NamedThing	COPII-coated vesicle budding	The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.	got7fsn_ti	ER vesicle budding|COPII vesicle budding|ER exit						tb	2009-12-06T09:21:16Z						biological_process											owl:Class	
GO:0031948	biolink:NamedThing	positive regulation of glucocorticoid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.	got7fsn_ti	up-regulation of glucocorticoid biosynthetic process|upregulation of glucocorticoid biosynthetic process|activation of glucocorticoid biosynthetic process|up regulation of glucocorticoid biosynthetic process|stimulation of glucocorticoid biosynthetic process													biological_process											owl:Class	
GO:0050070	biolink:NamedThing	lysolecithin acylmutase activity	Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine.	got7fsn_ti	lysolecithin 2,3-acylmutase activity|lysolecithin migratase activity											MetaCyc:LYSOLECITHIN-ACYLMUTASE-RXN|KEGG_REACTION:R03334|RHEA:24356|EC:5.4.1.1		molecular_function											owl:Class	
GO:0009254	biolink:NamedThing	peptidoglycan turnover	The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall.	got7fsn_ti	murein turnover										GO:0009287			biological_process											owl:Class	
GO:0000270	biolink:NamedThing	peptidoglycan metabolic process	The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.	got7fsn_ti	peptidoglycan metabolism|murein metabolic process|murein metabolism										GO:0009284			biological_process											owl:Class	
GO:0035139	biolink:NamedThing	pelvic fin morphogenesis	The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0097509	biolink:NamedThing	oxanine DNA N-glycosylase activity	DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination.	got7fsn_ti	oxanine-DNA glycosylase activity						pr	2013-09-26T16:03:58Z						molecular_function											owl:Class	
GO:0034512	biolink:NamedThing	box C/D RNA binding	Binding to a box C/D small nucleolar RNA.	got7fsn_ti	box C/D snoRNA binding|box C/D sRNA binding	https://github.com/geneontology/go-ontology/issues/20416												molecular_function											owl:Class	
GO:0048707	biolink:NamedThing	instar larval or pupal morphogenesis	The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0016711	biolink:NamedThing	flavonoid 3'-monooxygenase activity	Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O.	got7fsn_ti	flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating)|flavonoid 3'-hydroxylase activity|flavonoid 3-monooxygenase|NADPH:flavonoid-3'-hydroxylase activity|flavonoid 3-hydroxylase											EC:1.14.14.82|RHEA:16337|MetaCyc:FLAVONOID-3-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0032286	biolink:NamedThing	central nervous system myelin maintenance	The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.	got7fsn_ti	myelin maintenance in central nervous system													biological_process											owl:Class	
GO:0043217	biolink:NamedThing	myelin maintenance	The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath.	got7fsn_ti														biological_process											owl:Class	
GO:0060600	biolink:NamedThing	dichotomous subdivision of an epithelial terminal unit	The process in which an epithelial cord, rod or tube bifurcates at its end.	got7fsn_ti	primary branching of an epithelium						dph	2009-05-14T02:14:50Z						biological_process											owl:Class	
GO:0018856	biolink:NamedThing	benzoyl acetate-CoA ligase activity	Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA.	got7fsn_ti												SABIO-RK:5058|KEGG_REACTION:R05452|UM-BBD_reactionID:r0242		molecular_function											owl:Class	
GO:0043722	biolink:NamedThing	4-hydroxyphenylacetate decarboxylase activity	Catalysis of the reaction: (4-hydroxyphenyl)acetate + H(+) = 4-cresol + CO(2).	got7fsn_ti	4-Hpd activity|4-hydroxyphenylacetate carboxy-lyase activity|p-hydroxyphenylacetate decarboxylase activity|p-Hpd activity|4-(hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming)											MetaCyc:4.1.1.83-RXN|EC:4.1.1.83|RHEA:22732|KEGG_REACTION:R07312		molecular_function											owl:Class	
GO:0048483	biolink:NamedThing	autonomic nervous system development	The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.	got7fsn_ti														biological_process											owl:Class	
GO:0097242	biolink:NamedThing	amyloid-beta clearance	The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.	got7fsn_ti	beta-amyloid clearance						pr	2012-02-16T05:32:29Z						biological_process											owl:Class	
GO:0038094	biolink:NamedThing	Fc-gamma receptor signaling pathway	A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.	got7fsn_ti	Fc-gamma receptor signalling pathway						bf	2012-02-16T05:22:46Z						biological_process											owl:Class	
GO:0102280	biolink:NamedThing	choline monooxygenase activity (NADP-dependent)	Catalysis of the reaction: choline + NADP = betaine aldehyde + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-12582		molecular_function											owl:Class	
GO:0002351	biolink:NamedThing	serotonin production involved in inflammatory response	The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	serotonin production involved in acute inflammatory response													biological_process											owl:Class	
GO:0002532	biolink:NamedThing	production of molecular mediator involved in inflammatory response	The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	production of molecular mediator involved in acute inflammatory response|production of cellular mediator of acute inflammation													biological_process											owl:Class	
GO:0030354	biolink:NamedThing	melanin-concentrating hormone activity	The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals.	got7fsn_ti														molecular_function											owl:Class	
GO:0001652	biolink:NamedThing	granular component	A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.	got7fsn_ti	pars granulosa											NIF_Subcellular:sao1217793903		cellular_component											owl:Class	
GO:0018353	biolink:NamedThing	protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine	The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.	got7fsn_ti											GO:0018380	RESID:AA0131		biological_process											owl:Class	
GO:0017009	biolink:NamedThing	protein-phycocyanobilin linkage	The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.	got7fsn_ti												RESID:AA0131		biological_process											owl:Class	
GO:0031970	biolink:NamedThing	organelle envelope lumen	The region between the inner and outer lipid bilayers of an organelle envelope.	got7fsn_ti	organelle intermembrane space													cellular_component											owl:Class	
GO:0031974	biolink:NamedThing	membrane-enclosed lumen	The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.	got7fsn_ti														cellular_component											owl:Class	
GO:0000419	biolink:NamedThing	RNA polymerase V complex	RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits.	got7fsn_ti	DNA-directed RNA polymerase V complex|DNA-directed RNA polymerase IVb complex										GO:0080137			cellular_component											owl:Class	
GO:0015433	biolink:NamedThing	ABC-type peptide antigen transporter activity	Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.	got7fsn_ti	ATP-dependent peptide antigen transmembrane transporter activity|peptide antigen transporter activity|major histocompatibility peptide transporter activity|ATPase-coupled peptide antigen transmembrane transporter activity|peptide antigen-transporting ATPase activity|peptide antigen ABC transporter											Reactome:R-HSA-983144|TC:3.A.1.209.1|Reactome:R-HSA-1236949		molecular_function											owl:Class	
GO:0015440	biolink:NamedThing	ABC-type peptide transporter activity	Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.	got7fsn_ti	peptide ABC transporter|ATPase-coupled peptide transmembrane transporter activity|ATP-dependent peptide transmembrane transporter activity|peptide-transporting ATPase activity											EC:7.4.2.5|RHEA:14429|MetaCyc:3.6.3.43-RXN		molecular_function											owl:Class	
GO:1990067	biolink:NamedThing	intrachromosomal DNA recombination	The process of DNA recombination occurring within a single chromosome.	got7fsn_ti	intrastrand DNA recombination						tb	2013-03-27T21:11:35Z						biological_process											owl:Class	
GO:0044871	biolink:NamedThing	negative regulation by host of viral glycoprotein metabolic process	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process.	got7fsn_ti							jl	2014-09-18T14:28:48Z						biological_process											owl:Class	
GO:0044870	biolink:NamedThing	modulation by host of viral glycoprotein metabolic process	A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process.	got7fsn_ti							jl	2014-09-18T14:26:19Z						biological_process											owl:Class	
GO:0044518	biolink:NamedThing	positive regulation of vasoactive intestinal polypeptide receptor activity in other organism	A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism.	got7fsn_ti	positive regulation of VIP receptor activity in other organism						jl	2012-02-26T11:50:34Z						biological_process											owl:Class	
GO:0044517	biolink:NamedThing	modulation of vasoactive intestinal polypeptide receptor activity in other organism	The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism.	got7fsn_ti	regulation of vasoactive intestinal polypeptide receptor activity in other organism|modulation of VIP receptor activity in other organism						jl	2012-02-26T11:48:32Z						biological_process											owl:Class	
GO:0045323	biolink:NamedThing	interleukin-1 receptor complex	A protein complex that binds interleukin-1; comprises an alpha and a beta subunit.	got7fsn_ti	IL-1 receptor complex													cellular_component											owl:Class	
GO:0046849	biolink:NamedThing	bone remodeling	The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.	got7fsn_ti	bone remodelling											Wikipedia:Bone_remodeling		biological_process											owl:Class	
GO:0062105	biolink:NamedThing	RNA 2'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.	got7fsn_ti							dph	2019-01-23T14:23:00Z				RHEA:58956		molecular_function											owl:Class	
GO:0043771	biolink:NamedThing	cytidine kinase activity	Catalysis of the reaction: ATP + cytidine = ADP + CMP.	got7fsn_ti														molecular_function											owl:Class	
GO:0021586	biolink:NamedThing	pons maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	got7fsn_ti														biological_process											owl:Class	
GO:0001642	biolink:NamedThing	group III metabotropic glutamate receptor activity	A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0038007	biolink:NamedThing	netrin-activated signaling pathway	A series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.	got7fsn_ti	netrin-mediated signaling pathway|netrin signaling pathway|netrin-activated signal transduction pathway|netrin-activated signalling pathway						bf	2011-06-10T02:24:59Z						biological_process											owl:Class	
GO:0008911	biolink:NamedThing	lactaldehyde dehydrogenase activity	Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+.	got7fsn_ti	nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase activity|(S)-lactaldehyde:NAD+ oxidoreductase activity|L-lactaldehyde:NAD oxidoreductase activity											RHEA:14277|MetaCyc:LACTALDDEHYDROG-RXN|EC:1.2.1.22		molecular_function											owl:Class	
GO:0000215	biolink:NamedThing	tRNA 2'-phosphotransferase activity	Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.	got7fsn_ti	Tpt1|2'-phosphotransferase activity|yeast 2'-phosphotransferase activity|Tpt1p|2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity|2'-phospho-tRNA:NAD+ phosphotransferase activity										GO:0008665	MetaCyc:2.7.1.160-RXN|EC:2.7.1.160|RHEA:23324		molecular_function											owl:Class	
GO:0060576	biolink:NamedThing	intestinal epithelial cell development	The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-05-06T08:20:24Z						biological_process											owl:Class	
GO:0002066	biolink:NamedThing	columnar/cuboidal epithelial cell development	The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.	got7fsn_ti														biological_process											owl:Class	
GO:0008885	biolink:NamedThing	glutathionylspermidine synthase activity	Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.	got7fsn_ti	gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule]|glutathione:spermidine ligase (ADP-forming) activity|GSP synthetase activity|glutathionylspermidine synthetase activity|gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity											EC:6.3.1.8|RHEA:21272|MetaCyc:GSPSYN-RXN		molecular_function											owl:Class	
GO:0061586	biolink:NamedThing	positive regulation of transcription by transcription factor localization	Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.	got7fsn_ti							dph	2014-01-31T08:43:43Z						biological_process											owl:Class	
GO:0102303	biolink:NamedThing	resveratrol 3,5-O-dimethyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + trans-resveratrol <=> 2 S-adenosyl-L-homocysteine  + pterostilbene + 2 H+.	got7fsn_ti												MetaCyc:RXN-12805|RHEA:32103|EC:2.1.1.240		molecular_function											owl:Class	
GO:0021712	biolink:NamedThing	candelabrum cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0071382	biolink:NamedThing	cellular response to prostaglandin I stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.	got7fsn_ti							mah	2009-12-11T03:45:10Z						biological_process											owl:Class	
GO:0071379	biolink:NamedThing	cellular response to prostaglandin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.	got7fsn_ti							mah	2009-12-11T03:33:52Z						biological_process											owl:Class	
GO:0022034	biolink:NamedThing	rhombomere cell proliferation	The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0009583	biolink:NamedThing	detection of light stimulus	The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.	got7fsn_ti	perception of light|detection of light													biological_process											owl:Class	
GO:0052667	biolink:NamedThing	phosphomethylethanolamine N-methyltransferase activity	Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	N-methylethanolamine phosphate N-methyltransferase activity|S-adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase activity						ai	2011-04-11T11:36:47Z				KEGG_REACTION:R06868|RHEA:25321|MetaCyc:RXN-5642|EC:2.1.1.103		molecular_function											owl:Class	
GO:0150020	biolink:NamedThing	basal dendrite arborization	The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches.	got7fsn_ti							bc	2017-12-22T11:32:31Z						biological_process											owl:Class	
GO:0150019	biolink:NamedThing	basal dendrite morphogenesis	The process in which the anatomical structures of a basal dendrite are generated and organized.	got7fsn_ti							bc	2017-12-22T11:26:07Z						biological_process											owl:Class	
GO:0030496	biolink:NamedThing	midbody	A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.	got7fsn_ti												Wikipedia:Midbody_(cell_biology)		cellular_component											owl:Class	
GO:0003959	biolink:NamedThing	NADPH dehydrogenase activity	Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.	got7fsn_ti	NADPH2 diaphorase activity|TPNH dehydrogenase activity|triphosphopyridine nucleotide diaphorase activity|OYE|NADPH-dehydrogenase activity|triphosphopyridine diaphorase activity|dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity|reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity|NADPH2-dehydrogenase activity|old yellow enzyme|NADPH:(acceptor) oxidoreductase activity|NADPH diaphorase activity|NADPH:acceptor oxidoreductase activity|TPNH-diaphorase activity										GO:0016660|GO:0008468	RHEA:13149|EC:1.6.99.1|Reactome:R-HSA-9027631|Reactome:R-HSA-9018867|MetaCyc:NADPH-DEHYDROGENASE-RXN|Reactome:R-HSA-9027625|Reactome:R-HSA-9018901|UM-BBD_enzymeID:e0523|Reactome:R-HSA-9027632		molecular_function											owl:Class	
GO:0007364	biolink:NamedThing	establishment of terminal gap gene boundary	Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes.	got7fsn_ti														biological_process											owl:Class	
GO:0072278	biolink:NamedThing	metanephric comma-shaped body morphogenesis	The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.	got7fsn_ti							mah	2010-04-01T03:14:42Z						biological_process											owl:Class	
GO:0072049	biolink:NamedThing	comma-shaped body morphogenesis	The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.	got7fsn_ti							mah	2010-01-25T03:44:48Z						biological_process											owl:Class	
GO:0021709	biolink:NamedThing	cerebellar basket cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0140568	biolink:NamedThing	extraction of mislocalized protein from membrane	The removal of a mislocalized protein from a cellular membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20237					pg	2020-12-15T07:35:10Z						biological_process											owl:Class	
GO:0032333	biolink:NamedThing	activin secretion	The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.	got7fsn_ti														biological_process											owl:Class	
GO:0102807	biolink:NamedThing	cyanidin 3-O-glucoside 2''-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-O-sophoroside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-8176		molecular_function											owl:Class	
GO:0003035	biolink:NamedThing	detection of increased carbon dioxide by carotid body chemoreceptor signaling	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body.	got7fsn_ti	detection of increased carbon dioxide by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0015251	biolink:NamedThing	ammonium channel activity	Enables the facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti														molecular_function											owl:Class	
GO:0005261	biolink:NamedThing	cation channel activity	Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.	got7fsn_ti	non-selective cation channel activity|cation diffusion facilitator activity										GO:0015281|GO:0015338	Reactome:R-HSA-1296043|Reactome:R-HSA-1168376|Reactome:R-HSA-2089943|Reactome:R-HSA-169683|Reactome:R-HSA-426223|Reactome:R-HSA-4420052		molecular_function											owl:Class	
GO:1900588	biolink:NamedThing	violaceol I metabolic process	The chemical reactions and pathways involving violaceol I.	got7fsn_ti	violaceol I metabolism						di	2012-05-15T06:50:48Z						biological_process											owl:Class	
GO:1990533	biolink:NamedThing	Dom34-Hbs1 complex	A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.	got7fsn_ti	Dom34:Hbs1 complex						mcc	2014-11-07T20:49:03Z						cellular_component											owl:Class	
GO:0007130	biolink:NamedThing	synaptonemal complex assembly	The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.	got7fsn_ti	synaptonemal complex formation													biological_process											owl:Class	
GO:0140675	biolink:NamedThing	ATP-dependent histone unloader activity	Removing a histone or a histone complex from DNA.	got7fsn_ti	histone unloader activity|histone unloading activity	https://github.com/geneontology/go-ontology/issues/21733					pg	2021-06-29T12:43:10Z						molecular_function											owl:Class	
GO:0010676	biolink:NamedThing	positive regulation of cellular carbohydrate metabolic process	Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0045913	biolink:NamedThing	positive regulation of carbohydrate metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.	got7fsn_ti	activation of carbohydrate metabolic process|positive regulation of carbohydrate metabolism|up regulation of carbohydrate metabolic process|upregulation of carbohydrate metabolic process|stimulation of carbohydrate metabolic process|up-regulation of carbohydrate metabolic process													biological_process											owl:Class	
GO:0071173	biolink:NamedThing	spindle assembly checkpoint signaling	A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.	got7fsn_ti	signal transduction involved in spindle assembly checkpoint|spindle assembly checkpoint|SAC	https://github.com/geneontology/go-ontology/issues/20935			Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle assembly checkpoint (mitotic or meiotic).		mah	2009-11-23T12:36:57Z			GO:0072486			biological_process											owl:Class	
GO:0031577	biolink:NamedThing	spindle checkpoint signaling	A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.	got7fsn_ti	spindle checkpoint|signal transduction involved in spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20935			Note that this term should not be used for direct manual annotation as it should always be possible to choose either a mitotic or meiotic child term.						GO:0072416	Wikipedia:Spindle_checkpoint		biological_process											owl:Class	
GO:0046792	biolink:NamedThing	suppression by virus of host cell cycle arrest	Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur.	got7fsn_ti	viral inhibition of cell cycle arrest|negative regulation by virus of cell cycle arrest													biological_process											owl:Class	
GO:0019055	biolink:NamedThing	modification by virus of host cell cycle regulation	Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication.	got7fsn_ti	viral perturbation of cell cycle regulation													biological_process											owl:Class	
GO:0035922	biolink:NamedThing	foramen ovale closure	The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.	got7fsn_ti	foramen ovale of heart closure						bf	2011-07-05T01:39:54Z						biological_process											owl:Class	
GO:0016409	biolink:NamedThing	palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule.	got7fsn_ti												Reactome:R-HSA-203567|Reactome:R-HSA-5686304		molecular_function											owl:Class	
GO:0001674	biolink:NamedThing	female germ cell nucleus	The nucleus of the female germ cell, a reproductive cell in females.	got7fsn_ti	female germ-cell nucleus										GO:0043080			cellular_component											owl:Class	
GO:0050864	biolink:NamedThing	regulation of B cell activation	Any process that modulates the frequency, rate or extent of B cell activation.	got7fsn_ti	regulation of B lymphocyte activation|regulation of B-lymphocyte activation|regulation of B-cell activation													biological_process											owl:Class	
GO:0009275	biolink:NamedThing	Gram-positive-bacterium-type cell wall	A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria.	got7fsn_ti	cell wall of Gram-positive Bacteria|20-80nm peptidoglycan-based cell wall													cellular_component											owl:Class	
GO:0009274	biolink:NamedThing	peptidoglycan-based cell wall	A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.	got7fsn_ti	peptidoglycan|murein sacculus|envelope													cellular_component											owl:Class	
GO:0044001	biolink:NamedThing	migration in host	The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	migration within host													biological_process											owl:Class	
GO:0034582	biolink:NamedThing	3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0926		molecular_function											owl:Class	
GO:0072251	biolink:NamedThing	metanephric juxtaglomerulus cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-03-19T03:54:35Z						biological_process											owl:Class	
GO:0060927	biolink:NamedThing	cardiac pacemaker cell fate commitment	The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.	got7fsn_ti	pacemaker cell fate commitment						dph	2009-09-29T11:54:22Z						biological_process											owl:Class	
GO:0060923	biolink:NamedThing	cardiac muscle cell fate commitment	The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	got7fsn_ti	cardiomyocyte cell fate commitment|heart muscle cell fate commitment						dph	2009-09-29T11:13:32Z						biological_process											owl:Class	
GO:0072590	biolink:NamedThing	N-acetyl-L-aspartate-L-glutamate ligase activity	Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.	got7fsn_ti							mah	2011-02-10T03:20:41Z				Reactome:R-HSA-8942575		molecular_function											owl:Class	
GO:0052585	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound.	got7fsn_ti								2010-08-13T10:29:06Z				EC:1.4.5.-		molecular_function											owl:Class	
GO:0046510	biolink:NamedThing	UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity	Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP.	got7fsn_ti	sulfolipid synthase|UDP-sulphoquinovose:DAG sulphoquinovosyltransferase activity											MetaCyc:RXN-1224|RHEA:49468		molecular_function											owl:Class	
GO:1990859	biolink:NamedThing	cellular response to endothelin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).	got7fsn_ti							sl	2015-09-24T15:39:48Z						biological_process											owl:Class	
GO:0071375	biolink:NamedThing	cellular response to peptide hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.	got7fsn_ti	cellular response to polypeptide hormone stimulus						mah	2009-12-11T03:24:18Z						biological_process											owl:Class	
GO:0046205	biolink:NamedThing	nor-spermidine catabolic process	The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	got7fsn_ti	nor-spermidine breakdown|nor-spermidine catabolism|nor-spermidine degradation													biological_process											owl:Class	
GO:0006598	biolink:NamedThing	polyamine catabolic process	The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups.	got7fsn_ti	polyamine catabolism|polyamine breakdown|polyamine degradation													biological_process											owl:Class	
GO:0001730	biolink:NamedThing	2'-5'-oligoadenylate synthetase activity	Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.	got7fsn_ti	(2-5')oligo(A) synthetase activity|2'-5' oligoadenylate synthetase activity|oligo-2',5'-adenylate synthetase activity|2-5A synthetase activity											EC:2.7.7.84|Reactome:R-HSA-8985091|Reactome:R-HSA-8985104|MetaCyc:RXN-10798|MetaCyc:RXN-13648|Reactome:R-HSA-8983680|RHEA:34407		molecular_function											owl:Class	
GO:0061798	biolink:NamedThing	GTP 3',8'-cyclase activity	Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.	got7fsn_ti							dph	2016-10-06T14:26:11Z				MetaCyc:RXN-8340|RHEA:49576|EC:4.1.99.22		molecular_function											owl:Class	
GO:0018991	biolink:NamedThing	oviposition	The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.	got7fsn_ti	post-mating oviposition|egg-laying|egg laying										GO:0060403	Wikipedia:Oviposition		biological_process											owl:Class	
GO:0033791	biolink:NamedThing	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.	got7fsn_ti	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity|trihydroxycoprostanoyl-CoA oxidase activity|(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity|THC-CoA oxidase activity|THCA-CoA oxidase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity											MetaCyc:1.17.99.3-RXN|RHEA:15733|EC:1.17.99.3		molecular_function											owl:Class	
GO:0102342	biolink:NamedThing	3-oxo-cerotoyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA + NADP <=> 3-oxohexacosanoyl-CoA + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13301|EC:1.1.1.330		molecular_function											owl:Class	
GO:0097626	biolink:NamedThing	low-affinity L-arginine transmembrane transporter activity	Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low affinity L-arginine transmembrane transporter activity						pr	2014-08-20T14:24:22Z						molecular_function											owl:Class	
GO:0097625	biolink:NamedThing	low-affinity basic amino acid transmembrane transporter activity	Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low affinity basic amino acid transmembrane transporter activity						pr	2014-08-20T14:23:18Z						molecular_function											owl:Class	
GO:0045455	biolink:NamedThing	ecdysteroid metabolic process	The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.	got7fsn_ti	ecdysteroid metabolism													biological_process											owl:Class	
GO:0102238	biolink:NamedThing	geraniol kinase activity (ATP-dependent) activity	Catalysis of the reaction: geraniol + ATP = geranyl monophosphate + ADP + H+.	got7fsn_ti												MetaCyc:RXN-12307		molecular_function											owl:Class	
GO:0052670	biolink:NamedThing	geraniol kinase activity	Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate.	got7fsn_ti	geraniol phosphotransferase activity						ai	2011-04-11T03:14:02Z						molecular_function											owl:Class	
GO:0018481	biolink:NamedThing	4-hydroxymuconic-semialdehyde dehydrogenase activity	Catalysis of the reaction: <stereo>cis,trans</stereo>-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH.	got7fsn_ti	4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity											EC:1.2.1.61|RHEA:22420|MetaCyc:1.2.1.61-RXN|UM-BBD_reactionID:r0229|KEGG_REACTION:R05236		molecular_function											owl:Class	
GO:0010905	biolink:NamedThing	negative regulation of UDP-glucose catabolic process	Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	negative regulation of UDP-glucose catabolism													biological_process											owl:Class	
GO:0010677	biolink:NamedThing	negative regulation of cellular carbohydrate metabolic process	Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0018722	biolink:NamedThing	1-phenanthrol sulfotransferase activity	Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate.	got7fsn_ti	1-phenanthrol sulphotransferase activity											UM-BBD_reactionID:r0565		molecular_function											owl:Class	
GO:0019111	biolink:NamedThing	phenanthrol sulfotransferase activity	Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate.	got7fsn_ti	phenanthrol sulphotransferase activity													molecular_function											owl:Class	
GO:0031125	biolink:NamedThing	rRNA 3'-end processing	Any process involved in forming the mature 3' end of an rRNA molecule.	got7fsn_ti	rRNA 3' end processing													biological_process											owl:Class	
GO:0019121	biolink:NamedThing	peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine	The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan.	got7fsn_ti												RESID:AA0218		biological_process											owl:Class	
GO:0010458	biolink:NamedThing	exit from mitosis	The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	got7fsn_ti	exit from mitotic division|mitotic exit													biological_process											owl:Class	
GO:0044772	biolink:NamedThing	mitotic cell cycle phase transition	The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.	got7fsn_ti							jl	2013-02-28T13:09:33Z						biological_process											owl:Class	
GO:0042621	biolink:NamedThing	poly(3-hydroxyalkanoate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.	got7fsn_ti	PHA biosynthesis|poly(3-hydroxyalkanoate) biosynthesis|PHA biosynthetic process|poly(3-hydroxyalkanoate) formation|poly(3-hydroxyalkanoate) anabolism|poly(3-hydroxyalkanoate) synthesis													biological_process											owl:Class	
GO:0050036	biolink:NamedThing	L-threonate 3-dehydrogenase activity	Catalysis of the reaction: L-threonate + NAD(+) = 3-dehydro-L-threonate + H(+) + NADH.	got7fsn_ti	threonate dehydrogenase activity|L-threonic acid dehydrogenase activity|L-threonate:NAD+ 3-oxidoreductase activity											EC:1.1.1.129|KEGG_REACTION:R03733|MetaCyc:L-THREONATE-3-DEHYDROGENASE-RXN|RHEA:23376		molecular_function											owl:Class	
GO:0004400	biolink:NamedThing	histidinol-phosphate transaminase activity	Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.	got7fsn_ti	imidazolylacetolphosphate transaminase activity|imidazolylacetolphosphate aminotransferase activity|histidinol-phosphate aminotransferase activity|IAP transaminase activity|glutamic-imidazoleacetol phosphate transaminase activity|imidazoleacetol phosphate transaminase activity|imidazole acetol-phosphate transaminase activity|histidinol phosphate aminotransferase activity|L-histidinol phosphate aminotransferase activity|L-histidinol-phosphate:2-oxoglutarate aminotransferase activity|histidine:imidazoleacetol phosphate transaminase activity											EC:2.6.1.9|MetaCyc:HISTAMINOTRANS-RXN|RHEA:23744		molecular_function											owl:Class	
GO:0034467	biolink:NamedThing	esterosome lumen	The volume enclosed by the membrane of an esterosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0052871	biolink:NamedThing	alpha-tocopherol omega-hydroxylase activity	Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O .	got7fsn_ti	alpha-tocopherol 13-hydroxylase activity						ai	2012-01-30T03:06:27Z				MetaCyc:RXN-11003		molecular_function											owl:Class	
GO:0052870	biolink:NamedThing	tocopherol omega-hydroxylase activity	Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O .	got7fsn_ti	tocopherol 13-hydroxylase activity						ai	2012-01-30T03:06:27Z						molecular_function											owl:Class	
GO:0004766	biolink:NamedThing	spermidine synthase activity	Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.	got7fsn_ti	putrescine aminopropyltransferase activity|aminopropyltransferase activity|spermidine synthetase activity|SpeE|S-adenosylmethioninamine:putrescine 3-aminopropyltransferase activity											EC:2.5.1.16|RHEA:12721|MetaCyc:SPERMIDINESYN-RXN|Reactome:R-HSA-351215		molecular_function											owl:Class	
GO:0106305	biolink:NamedThing	mannogen catabolic process	The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.	got7fsn_ti	beta-1,2-mannan catabolism|mannogen breakdown|mannogen degradation|beta-1,2-mannan catabolic process|mannogen catabolism						hjd	2020-09-09T13:55:16Z						biological_process											owl:Class	
GO:0097164	biolink:NamedThing	ammonium ion metabolic process	The chemical reactions and pathways involving the ammonium ion.	got7fsn_ti	ammonium ion metabolism|ammonium metabolic process						pr	2011-09-28T04:21:30Z						biological_process											owl:Class	
GO:0033338	biolink:NamedThing	medial fin development	The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.	got7fsn_ti	median fin development													biological_process											owl:Class	
GO:0033333	biolink:NamedThing	fin development	The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0047679	biolink:NamedThing	arginine racemase activity	Catalysis of the reaction: L-arginine = D-arginine.	got7fsn_ti												MetaCyc:ARGININE-RACEMASE-RXN|EC:5.1.1.9|RHEA:18069		molecular_function											owl:Class	
GO:0050059	biolink:NamedThing	lombricine kinase activity	Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine.	got7fsn_ti	ATP:lombricine N-phosphotransferase activity											RHEA:23292|EC:2.7.3.5|MetaCyc:LOMBRICINE-KINASE-RXN		molecular_function											owl:Class	
GO:0048765	biolink:NamedThing	root hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.	got7fsn_ti														biological_process											owl:Class	
GO:0048764	biolink:NamedThing	trichoblast maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state.	got7fsn_ti														biological_process											owl:Class	
GO:0052638	biolink:NamedThing	indole-3-butyrate beta-glucosyltransferase activity	Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP.	got7fsn_ti	UDP-glucose:(indol-3-yl)butyrate beta-D-glucosyltransferase activity|uridine diphosphoglucose-indolebutyrate glucosyltransferase activity|UDPglucose:indole-3-butyrate beta-D-glucosyltransferase activity|IBA-Glc synthetase activity|indole-3-butyric acid glucosyltransferase activity|indol-3-ylbutyrylglucose synthase activity|UDPG-indol-3-ylbutyryl glucosyl transferase activity|IBA-glucose synthase activity|UDP-glucose:indol-3-ylbutyrate glucosyl-transferase activity|UDP-glucose:indol-3-ylbutyrate glucosyltransferase activity|IBAGlu synthase activity											RHEA:62708|MetaCyc:RXN-11655		molecular_function											owl:Class	
GO:0052579	biolink:NamedThing	(+)-pulegone reductase, (+)-isomenthone as substrate, activity	Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+.	got7fsn_ti	(+)-isomenthone:NADP+ oxidoreductase activity						ai	2010-08-09T04:28:00Z				EC:1.3.1.81|MetaCyc:RXN-5164		molecular_function											owl:Class	
GO:0070643	biolink:NamedThing	vitamin D 25-hydroxylase activity	Catalysis of the hydroxylation of C-25 of any form of vitamin D.	got7fsn_ti	vitamin D2 25-hydroxylase activity|calciferol 25-hydroxylase activity|ergocalciferol 25-hydroxylase activity|cholecalciferol 25-hydroxylase activity						mah	2009-05-08T03:42:29Z						molecular_function											owl:Class	
GO:0097705	biolink:NamedThing	vascular endothelial cell response to pulsatile fluid shear stress	Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell.	got7fsn_ti	blood vessel endothelial cell response to pulsatile fluid shear stress						pr	2016-01-27T14:22:44Z						biological_process											owl:Class	
GO:0097699	biolink:NamedThing	vascular endothelial cell response to fluid shear stress	Any response to fluid shear stress in a vascular endothelial cell.	got7fsn_ti	blood vessel endothelial cell response to fluid shear stress						pr	2016-01-27T12:37:32Z						biological_process											owl:Class	
GO:0032020	biolink:NamedThing	ISG15-protein conjugation	The covalent addition to a protein of ISG15, a ubiquitin-like protein.	got7fsn_ti														biological_process											owl:Class	
GO:0042641	biolink:NamedThing	actomyosin	Any complex of actin, myosin, and accessory proteins.	got7fsn_ti	actomyosin structure|actomyosin complex													cellular_component											owl:Class	
GO:0045135	biolink:NamedThing	poly(beta-D-mannuronate) lyase activity	Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.	got7fsn_ti	alginate lyase I activity|alginate lyase activity|poly(beta-D-1,4-mannuronide) lyase activity|alginase I|alginase activity|poly(mana) alginate lyase activity											EC:4.2.2.3|MetaCyc:4.2.2.3-RXN		molecular_function											owl:Class	
GO:0086014	biolink:NamedThing	atrial cardiac muscle cell action potential	An action potential that occurs in an atrial cardiac muscle cell.	got7fsn_ti							tb	2011-11-10T08:49:13Z						biological_process											owl:Class	
GO:0086002	biolink:NamedThing	cardiac muscle cell action potential involved in contraction	An action potential that occurs in a cardiac muscle cell and is involved in its contraction.	got7fsn_ti							tb	2011-11-10T07:45:11Z						biological_process											owl:Class	
GO:0072237	biolink:NamedThing	metanephric proximal tubule development	The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.	got7fsn_ti							mah	2010-03-18T03:46:54Z						biological_process											owl:Class	
GO:0072234	biolink:NamedThing	metanephric nephron tubule development	The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.	got7fsn_ti							mah	2010-03-18T03:41:23Z						biological_process											owl:Class	
GO:0045686	biolink:NamedThing	negative regulation of glial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.	got7fsn_ti	negative regulation of neuroglia differentiation|down-regulation of glial cell differentiation|inhibition of glial cell differentiation|negative regulation of glia cell differentiation|down regulation of glial cell differentiation|downregulation of glial cell differentiation													biological_process											owl:Class	
GO:0010114	biolink:NamedThing	response to red light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti	response to red light stimulus													biological_process											owl:Class	
GO:0070210	biolink:NamedThing	Rpd3L-Expanded complex	A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.	got7fsn_ti	Clr6-LE complex													cellular_component											owl:Class	
GO:0044083	biolink:NamedThing	modulation by symbiont of host Rho protein signal transduction	Any process in which a symbiont organism modulates the frequency, rate or extent of Rho protein signal transduction in its host organism.	got7fsn_ti	modulation of host Rho protein signalling by symbiont|regulation by symbiont of host Rho protein signal transduction|modulation by symbiont of host Rho protein mediated signal transduction|modulation by symbiont of host Rho protein-mediated signal transduction|modulation of host Rho protein signal transduction by symbiont|modulation of host Rho protein signaling by symbiont													biological_process											owl:Class	
GO:0044082	biolink:NamedThing	modulation by symbiont of host small GTPase mediated signal transduction	Any process in which a symbiont organism modulates the frequency, rate or extent of small GTPase mediated signal transduction in its host organism.	got7fsn_ti	regulation by symbiont of host small GTPase mediated signal transduction|modulation of host small GTPase mediated signal transduction by symbiont													biological_process											owl:Class	
GO:0110129	biolink:NamedThing	SHREC2 complex	A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.	got7fsn_ti							kmv	2018-09-25T21:25:41Z						cellular_component											owl:Class	
GO:0006704	biolink:NamedThing	glucocorticoid biosynthetic process	The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.	got7fsn_ti	glucocorticoid anabolism|glucocorticoid formation|glucocorticoid synthesis|glucocorticoid biosynthesis													biological_process											owl:Class	
GO:0006694	biolink:NamedThing	steroid biosynthetic process	The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.	got7fsn_ti	steroid biosynthesis|steroidogenesis|steroid synthesis|steroid anabolism|steroid formation											Wikipedia:Steroid_metabolisms#Steroid_biosynthesis		biological_process											owl:Class	
GO:0018398	biolink:NamedThing	peptidyl-phenylalanine bromination to L-3'-bromophenylalanine	The bromination of peptidyl-phenylalanine to form L-3'-bromophenylalanine.	got7fsn_ti												RESID:AA0175		biological_process											owl:Class	
GO:0060394	biolink:NamedThing	negative regulation of pathway-restricted SMAD protein phosphorylation	Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	got7fsn_ti														biological_process											owl:Class	
GO:0090101	biolink:NamedThing	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.	got7fsn_ti	negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway						tb	2009-11-13T10:56:52Z						biological_process											owl:Class	
GO:0015189	biolink:NamedThing	L-lysine transmembrane transporter activity	Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.	got7fsn_ti	lysine permease activity|histidine/arginine/lysine/ornithine porter activity|L-lysine permease										GO:0005293			molecular_function											owl:Class	
GO:0044627	biolink:NamedThing	modulation of complement activation, classical pathway in other organism	A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism.	got7fsn_ti	regulation of complement activation, classical pathway in other organism						jl	2012-07-05T12:55:53Z						biological_process											owl:Class	
GO:0052617	biolink:NamedThing	ent-kaur-16-en-19-al oxidase activity	Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate.	got7fsn_ti												EC:1.14.14.86|RHEA:10928|MetaCyc:RXN-7580		molecular_function											owl:Class	
GO:0007480	biolink:NamedThing	imaginal disc-derived leg morphogenesis	The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0070513	biolink:NamedThing	death domain binding	Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.	got7fsn_ti					For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'.									molecular_function											owl:Class	
GO:0034336	biolink:NamedThing	misfolded RNA binding	Binding to an RNA molecule that has assumed an incorrect conformation.	got7fsn_ti	RNA chaperone													molecular_function											owl:Class	
GO:0030120	biolink:NamedThing	vesicle coat	A membrane coat found on a coated vesicle.	got7fsn_ti												NIF_Subcellular:sao1177708494		cellular_component											owl:Class	
GO:0051435	biolink:NamedThing	BH4 domain binding	Binding to a BH4 protein domain, present in Bcl-2 family members. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0051400	biolink:NamedThing	BH domain binding	Binding to a Bcl-2 homology (BH) protein domain. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains.	got7fsn_ti	Bcl-2 homology domain binding													molecular_function											owl:Class	
GO:0071573	biolink:NamedThing	shelterin complex assembly	The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase.	got7fsn_ti	Pot1-Tpz1 complex assembly|Pot1 complex assembly|telosome assembly|shelterin complex formation						mah	2010-01-26T01:45:20Z						biological_process											owl:Class	
GO:0045514	biolink:NamedThing	interleukin-16 receptor binding	Binding to an interleukin-16 receptor.	got7fsn_ti	IL-16|interleukin-16 receptor ligand													molecular_function											owl:Class	
GO:0048472	biolink:NamedThing	threonine-phosphate decarboxylase activity	Catalysis of the reaction: O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO(2).	got7fsn_ti	L-threonine O-3-phosphate carboxy-lyase [(R)-1-aminopropan-2-yl-phosphate-forming]|CobD|L-threonine O-3-phosphate carboxy-lyase activity|L-threonine-O-3-phosphate decarboxylase activity											RHEA:11492|MetaCyc:4.1.1.81-RXN|EC:4.1.1.81|KEGG_REACTION:R06530		molecular_function											owl:Class	
GO:0045006	biolink:NamedThing	DNA deamination	The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil.	got7fsn_ti														biological_process											owl:Class	
GO:0060792	biolink:NamedThing	sweat gland development	The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.	got7fsn_ti							dph	2009-08-04T12:35:12Z						biological_process											owl:Class	
GO:0120212	biolink:NamedThing	sperm head-tail coupling apparatus	A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head.	got7fsn_ti	HTCA|head-tail coupling apparatus						krc	2019-06-07T23:08:46Z						cellular_component											owl:Class	
GO:0060080	biolink:NamedThing	inhibitory postsynaptic potential	A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.	got7fsn_ti	IPSP|regulation of inhibitory post-synaptic membrane potential													biological_process											owl:Class	
GO:0009906	biolink:NamedThing	response to photoperiod, blue light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.	got7fsn_ti														biological_process											owl:Class	
GO:0016290	biolink:NamedThing	palmitoyl-CoA hydrolase activity	Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.	got7fsn_ti	fatty acyl thioesterase I|long-chain fatty-acyl-CoA hydrolase activity|palmityl thioesterase activity|palmityl thioesterase I|palmityl-CoA deacylase activity|palmitoyl-CoA deacylase activity|palmitoyl coenzyme A hydrolase activity|palmitoyl thioesterase activity										GO:0016293	MetaCyc:PWY-5148|EC:3.1.2.2|MetaCyc:PALMITOYL-COA-HYDROLASE-RXN|RHEA:16645		molecular_function											owl:Class	
GO:0047617	biolink:NamedThing	acyl-CoA hydrolase activity	Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.	got7fsn_ti	acyl-CoA thioesterase I activity|acyl-CoA thioesterase activity|acyl-CoA thioesterase II activity|thioesterase II|acyl-CoA thiolesterase activity|acyl coenzyme A thioesterase activity|acyl coenzyme A hydrolase activity|thioesterase B										GO:0016292|GO:0008778|GO:0016291	EC:3.1.2.20|Reactome:R-HSA-5690043|Reactome:R-HSA-5690066|RHEA:16781|MetaCyc:ACYL-COA-HYDROLASE-RXN|Reactome:R-HSA-5690042		molecular_function											owl:Class	
GO:0019785	biolink:NamedThing	ISG15-specific protease activity	Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates.	got7fsn_ti												Reactome:R-HSA-1678841|Reactome:R-HSA-5653786		molecular_function											owl:Class	
GO:0080068	biolink:NamedThing	5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate.	got7fsn_ti							dhl	2009-04-13T04:06:59Z				MetaCyc:RXNQT-4330		molecular_function											owl:Class	
GO:0047364	biolink:NamedThing	desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H(+).	got7fsn_ti	PAPS-desulfoglucosinolate sulfotransferase activity|desulphoglucosinolate sulphotransferase activity|3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase activity|3'-phosphoadenylyl-sulfate:desulfoglucosinolate sulfotransferase activity											EC:2.8.2.24|MetaCyc:2.8.2.24-RXN|KEGG_REACTION:R03214|RHEA:20281		molecular_function											owl:Class	
GO:0102167	biolink:NamedThing	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-serine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-serine.	got7fsn_ti												MetaCyc:RXN-11892|RHEA:48876|EC:3.2.1.169		molecular_function											owl:Class	
GO:0035916	biolink:NamedThing	modulation of calcium channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism.	got7fsn_ti							bf	2011-07-01T11:51:38Z						biological_process											owl:Class	
GO:0017025	biolink:NamedThing	TBP-class protein binding	Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).	got7fsn_ti	TBP binding|TBP-related factor (TRF) protein binding|TATA-binding protein binding													molecular_function											owl:Class	
GO:0106210	biolink:NamedThing	culmorin biosynthetic process	The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris.	got7fsn_ti	culmorin formation|culmorin synthesis|culmorin anabolism|culmorin biosynthesis						hjd	2019-05-13T17:30:41Z						biological_process											owl:Class	
GO:0044849	biolink:NamedThing	estrous cycle	A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.	got7fsn_ti							jl	2014-07-16T13:41:42Z				Wikipedia:Estrous_cycle		biological_process											owl:Class	
GO:0032070	biolink:NamedThing	regulation of deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.	got7fsn_ti	deoxyribonuclease regulator|DNase regulator													biological_process											owl:Class	
GO:0070545	biolink:NamedThing	PeBoW complex	A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.	got7fsn_ti														cellular_component											owl:Class	
GO:0072286	biolink:NamedThing	metanephric connecting tubule development	The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.	got7fsn_ti	metanephric connecting duct development						mah	2010-04-09T03:30:09Z						biological_process											owl:Class	
GO:0048318	biolink:NamedThing	axial mesoderm development	The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.	got7fsn_ti														biological_process											owl:Class	
GO:0007498	biolink:NamedThing	mesoderm development	The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0008696	biolink:NamedThing	4-amino-4-deoxychorismate lyase activity	Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate.	got7fsn_ti	ADC lyase activity|para-aminobenzoic acid (PABA) synthase|para-aminobenzoic acid synthase|enzyme X activity|4-amino-4-deoxychorismate pyruvate-lyase activity|4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)|p-aminobenzoate synthetase|aminodeoxychorismate lyase activity				Note that the name 'para-amino benzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate.							RHEA:16201|MetaCyc:ADCLY-RXN|KEGG_REACTION:R05553|EC:4.1.3.38		molecular_function											owl:Class	
GO:0047112	biolink:NamedThing	pyruvate oxidase activity	Catalysis of the reaction: H(+) + O(2) + phosphate + pyruvate = acetyl phosphate + CO(2) + H(2)O(2).	got7fsn_ti	phosphate-dependent pyruvate oxidase activity|pyruvic oxidase activity|pyruvate:oxygen 2-oxidoreductase (phosphorylating)											MetaCyc:1.2.3.3-RXN|KEGG_REACTION:R00207|RHEA:20848|EC:1.2.3.3		molecular_function											owl:Class	
GO:0016852	biolink:NamedThing	sirohydrochlorin cobaltochelatase activity	Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.	got7fsn_ti	sirohydrochlorin cobalt-lyase activity|cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming)|CbiX|anaerobic cobalt chelatase activity|CbiK|CbiXS											MetaCyc:4.99.1.3-RXN|RHEA:15893|EC:4.99.1.3		molecular_function											owl:Class	
GO:0000403	biolink:NamedThing	Y-form DNA binding	Binding to a DNA segment shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end.	got7fsn_ti	splayed Y-form DNA binding|forked DNA binding													molecular_function											owl:Class	
GO:0004026	biolink:NamedThing	alcohol O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester.	got7fsn_ti	alcohol acetyltransferase activity|acetyl-CoA:alcohol O-acetyltransferase activity|AATASE activity											EC:2.3.1.84|MetaCyc:ALCOHOL-O-ACETYLTRANSFERASE-RXN|RHEA:17229		molecular_function											owl:Class	
GO:0008871	biolink:NamedThing	aminoglycoside 2''-nucleotidyltransferase activity	Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside.	got7fsn_ti	NTP:gentamicin 2''-nucleotidyltransferase activity|gentamicin 2''-nucleotidyltransferase activity|gentamicin 2''- adenylyltransferase activity|gentamycin 2''-nucleotidyltransferase activity|2''-aminoglycoside nucleotidyltransferase activity											EC:2.7.7.46|MetaCyc:2.7.7.46-RXN		molecular_function											owl:Class	
GO:0034068	biolink:NamedThing	aminoglycoside nucleotidyltransferase activity	Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.	got7fsn_ti	streptomycin adenylate synthetase activity|streptomycin adenylylase activity|streptomycin adenylyltransferase activity|streptomycin adenyltransferase activity|aminoglycoside adenylyltransferase activity|streptomycin-spectinomycin adenylyltransferase activity													molecular_function											owl:Class	
GO:0031699	biolink:NamedThing	beta-3 adrenergic receptor binding	Binding to a beta-3 adrenergic receptor.	got7fsn_ti	beta-3 adrenergic receptor ligand													molecular_function											owl:Class	
GO:0018525	biolink:NamedThing	4-hydroxybenzoyl-CoA reductase activity	Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin.	got7fsn_ti	4-hydroxybenzoyl-coA:(acceptor) oxidoreductase activity|4-hydroxybenzoyl-coA reductase (dehydroxylating) activity											KEGG_REACTION:R05316|UM-BBD_reactionID:r0158|MetaCyc:OHBENZCOARED-RXN|RHEA:29603|EC:1.1.7.1		molecular_function											owl:Class	
GO:0098581	biolink:NamedThing	detection of external biotic stimulus	The series of events in which an external biotic stimulus is detected and converted into a molecular signal.  An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated.	got7fsn_ti	detection of exogenous biotic stimulus						dos	2014-01-22T14:20:16Z						biological_process											owl:Class	
GO:0102284	biolink:NamedThing	L-threo-sphinganine reductase activity	Catalysis of the reaction: L-threo-sphinganine + NADP <=> H+ + NADPH + 3-dehydrosphinganinium(1+).	got7fsn_ti												MetaCyc:RXN-12645		molecular_function											owl:Class	
GO:0010434	biolink:NamedThing	bract formation	The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.	got7fsn_ti														biological_process											owl:Class	
GO:0007208	biolink:NamedThing	phospholipase C-activating serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	activation of phospholipase C activity by serotonin receptor signalling pathway|serotonin receptor, phospholipase C activating pathway|activation of phospholipase C activity by serotonin receptor signaling pathway													biological_process											owl:Class	
GO:0000477	biolink:NamedThing	generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	got7fsn_ti	processing at C1													biological_process											owl:Class	
GO:0000967	biolink:NamedThing	rRNA 5'-end processing	Any process involved in forming the mature 5' end of an rRNA molecule.	got7fsn_ti	rRNA 5' end processing													biological_process											owl:Class	
GO:0031024	biolink:NamedThing	interphase microtubule organizing center assembly	The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center.	got7fsn_ti	interphase microtubule organising center formation|interphase microtubule organizing centre assembly|interphase microtubule organizing center biogenesis|interphase microtubule organising center biosynthesis													biological_process											owl:Class	
GO:0031023	biolink:NamedThing	microtubule organizing center organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.	got7fsn_ti	microtubule organising center organisation|microtubule organizing center organization and biogenesis													biological_process											owl:Class	
GO:0019603	biolink:NamedThing	toluene oxidation via 4-hydroxytoluene	The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol).	got7fsn_ti												MetaCyc:TOLUENE-DEG-4-OH-PWY		biological_process											owl:Class	
GO:0051081	biolink:NamedThing	nuclear membrane disassembly	The controlled breakdown of the nuclear membranes, for example during  cellular division.	got7fsn_ti	nuclear envelope disassembly|nuclear envelope degradation|nuclear envelope catabolism|nuclear envelope breakdown													biological_process											owl:Class	
GO:0030397	biolink:NamedThing	membrane disassembly	The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.	got7fsn_ti	membrane catabolism|membrane breakdown|membrane degradation													biological_process											owl:Class	
GO:0097421	biolink:NamedThing	liver regeneration	The regrowth of lost or destroyed liver.	got7fsn_ti							pr	2012-11-07T10:22:43Z						biological_process											owl:Class	
GO:0001889	biolink:NamedThing	liver development	The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.	got7fsn_ti														biological_process											owl:Class	
GO:0031758	biolink:NamedThing	Edg-5 sphingosine 1-phosphate receptor binding	Binding to an Edg-5 sphingosine 1-phosphate receptor.	got7fsn_ti	Edg-5 sphingosine 1-phosphate receptor ligand													molecular_function											owl:Class	
GO:0071740	biolink:NamedThing	IgD B cell receptor complex	An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	got7fsn_ti	membrane-bound IgD|surface IgD				Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0052489	biolink:NamedThing	negative regulation by host of symbiont programmed cell death	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	down-regulation by host of symbiont programmed cell death|downregulation by host of symbiont programmed cell death|inhibition of symbiont programmed cell death|down regulation by host of symbiont programmed cell death|inhibition by host of symbiont programmed cell death													biological_process											owl:Class	
GO:0051711	biolink:NamedThing	negative regulation of killing of cells of other organism	Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism.	got7fsn_ti	down-regulation of killing of cells of another organism|negative regulation of killing of cells of another organism|down regulation of killing of cells of another organism|inhibition of killing of cells of another organism|negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction|downregulation of killing of cells of another organism	https://github.com/geneontology/go-ontology/issues/20287									GO:0052490			biological_process											owl:Class	
GO:0097552	biolink:NamedThing	mitochondrial double-strand break repair via homologous recombination	The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences.	got7fsn_ti	mtDSB repair via homologous recombination				Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable.		pr	2014-01-22T10:09:10Z						biological_process											owl:Class	
GO:0097551	biolink:NamedThing	mitochondrial double-strand break repair	The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.	got7fsn_ti	mtDSB repair				Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable.		pr	2014-01-22T10:06:54Z						biological_process											owl:Class	
GO:0032047	biolink:NamedThing	mitosome	A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria.	got7fsn_ti	crypton				In Giardia species, mitosomes are sometimes present between the two nuclei.							Wikipedia:Mitosome		cellular_component											owl:Class	
GO:0102140	biolink:NamedThing	heparan sulfate N-deacetylase activity	Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine.	got7fsn_ti												MetaCyc:RXN-11557		molecular_function											owl:Class	
GO:0001505	biolink:NamedThing	regulation of neurotransmitter levels	Any process that modulates levels of neurotransmitter.	got7fsn_ti														biological_process											owl:Class	
GO:0050446	biolink:NamedThing	azobenzene reductase activity	Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+.	got7fsn_ti	NADPH2:4-(dimethylamino)azobenzene oxidoreductase activity|NADPH-dependent azoreductase activity|NADPH:4-(dimethylamino)azobenzene oxidoreductase activity|dimethylaminobenzene reductase activity|azo-dye reductase activity|azoreductase activity|N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase activity|orange I azoreductase activity|azo reductase activity|p-dimethylaminoazobenzene azoreductase activity|new coccine (NC)-reductase|nicotinamide adenine dinucleotide (phosphate) azoreductase activity|NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase activity|NADPH2-dependent azoreductase activity|dibromopropylaminophenylazobenzoic azoreductase activity|NC-reductase activity|New coccine (NC)-reductase activity|methyl red azoreductase activity|N,N-dimethyl-4-phenylazoaniline azoreductase activity|orange II azoreductase activity|p-aminoazobenzene reductase activity											RHEA:16269|UM-BBD_reactionID:r0808|MetaCyc:AZOBENZENE-REDUCTASE-RXN|EC:1.7.1.6		molecular_function											owl:Class	
GO:0071526	biolink:NamedThing	semaphorin-plexin signaling pathway	A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.	got7fsn_ti	semaphorin-plexin signalling pathway						mah	2010-01-07T03:48:07Z						biological_process											owl:Class	
GO:0072194	biolink:NamedThing	kidney smooth muscle tissue development	The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.	got7fsn_ti							mah	2010-03-01T02:05:30Z						biological_process											owl:Class	
GO:0048745	biolink:NamedThing	smooth muscle tissue development	The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0015079	biolink:NamedThing	potassium ion transmembrane transporter activity	Enables the transfer of potassium ions (K+) from one side of a membrane to the other.	got7fsn_ti	potassium transporter activity|potassium uptake transmembrane transporter activity|potassium uptake permease activity										GO:0015388|GO:0022817	RHEA:29463		molecular_function											owl:Class	
GO:0035677	biolink:NamedThing	posterior lateral line neuromast hair cell development	The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti							bf	2011-02-14T11:04:57Z						biological_process											owl:Class	
GO:0035675	biolink:NamedThing	neuromast hair cell development	The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti							bf	2011-02-14T11:01:42Z						biological_process											owl:Class	
GO:0043446	biolink:NamedThing	cellular alkane metabolic process	The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells.	got7fsn_ti	alkane metabolism													biological_process											owl:Class	
GO:0034428	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'	The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.	got7fsn_ti	5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process													biological_process											owl:Class	
GO:0033793	biolink:NamedThing	aureusidin synthase activity	Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O.	got7fsn_ti	2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity													molecular_function											owl:Class	
GO:0046993	biolink:NamedThing	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen.	got7fsn_ti												EC:1.21.3.-		molecular_function											owl:Class	
GO:0000710	biolink:NamedThing	meiotic mismatch repair	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0052494	biolink:NamedThing	occlusion by host of symbiont vascular system	The process in which an organism reduces the flow of fluid within its symbiont's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0035002	biolink:NamedThing	liquid clearance, open tracheal system	The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.	got7fsn_ti	tracheal liquid clearance													biological_process											owl:Class	
GO:0042045	biolink:NamedThing	epithelial fluid transport	The directed movement of fluid across epithelia.	got7fsn_ti														biological_process											owl:Class	
GO:0002411	biolink:NamedThing	T cell tolerance induction to tumor cell	A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.	got7fsn_ti														biological_process											owl:Class	
GO:0002424	biolink:NamedThing	T cell mediated immune response to tumor cell	An immune response mediated by a T cell triggered in response to the presence of a tumor cell.	got7fsn_ti					Note that this term includes tolerogenic responses to tumor cells mediated by responding T cells.									biological_process											owl:Class	
GO:0035967	biolink:NamedThing	cellular response to topologically incorrect protein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.	got7fsn_ti	cellular response to misfolded or unfolded protein						bf	2011-08-03T11:44:50Z						biological_process											owl:Class	
GO:0035852	biolink:NamedThing	horizontal cell localization	Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina.	got7fsn_ti	horizontal cell localisation|retinal horizontal cell positioning|laminar positioning of retinal horizontal cell|horizontal cell positioning						bf	2011-05-11T01:56:40Z						biological_process											owl:Class	
GO:0051674	biolink:NamedThing	localization of cell	Any process in which a cell is transported to, and/or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of cell localization|localisation of cell|establishment and maintenance of localization of cell|cell localization													biological_process											owl:Class	
GO:0038123	biolink:NamedThing	toll-like receptor TLR1:TLR2 signaling pathway	A series of molecular signals initiated by the binding of a heterodimeric TLR1:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	TLR2:TLR1 signaling pathway|toll-like receptor TLR1:TLR2 signalling pathway						bf	2012-03-23T10:20:13Z						biological_process											owl:Class	
GO:0030372	biolink:NamedThing	high molecular weight B cell growth factor receptor binding	Binding to a high molecular weight B cell growth factor receptor.	got7fsn_ti	high molecular weight B-cell growth factor receptor binding|high molecular weight B lymphocyte growth factor receptor binding|high molecular weight B-lymphocyte growth factor receptor binding|high molecular weight B cell growth factor receptor ligand													molecular_function											owl:Class	
GO:0016429	biolink:NamedThing	tRNA (adenine-N1-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine.	got7fsn_ti	transfer ribonucleate adenine 1-methyltransferase activity|adenine-1-methylase activity|1-methyladenine transfer RNA methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-1-N-)-methyltransferase activity|transfer RNA (adenine-1) methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-N1-)-methyltransferase activity											Reactome:R-HSA-6787594|Reactome:R-HSA-6783492|Reactome:R-HSA-6787525		molecular_function											owl:Class	
GO:0016426	biolink:NamedThing	tRNA (adenine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine.	got7fsn_ti														molecular_function											owl:Class	
GO:1990761	biolink:NamedThing	growth cone lamellipodium	A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments.	got7fsn_ti							sl	2015-06-05T22:31:19Z						cellular_component											owl:Class	
GO:0030027	biolink:NamedThing	lamellipodium	A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.	got7fsn_ti												Wikipedia:Lamellipodia		cellular_component											owl:Class	
GO:0031535	biolink:NamedThing	plus-end directed microtubule sliding	The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.	got7fsn_ti														biological_process											owl:Class	
GO:0032034	biolink:NamedThing	myosin II head/neck binding	Binding to the head/neck region of a myosin II heavy chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0032038	biolink:NamedThing	myosin II heavy chain binding	Binding to a heavy chain of a myosin II complex.	got7fsn_ti														molecular_function											owl:Class	
GO:1990619	biolink:NamedThing	histone H3-K9 deacetylation	The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone.	got7fsn_ti							al	2015-01-23T17:27:16Z						biological_process											owl:Class	
GO:0007281	biolink:NamedThing	germ cell development	The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.	got7fsn_ti	germ-cell development|primordial germ cell development													biological_process											owl:Class	
GO:0016737	biolink:NamedThing	oxidoreductase activity, acting on reduced flavodoxin as donor	Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti												EC:1.19.-.-		molecular_function											owl:Class	
GO:0052906	biolink:NamedThing	tRNA (guanine(37)-N(1))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.	got7fsn_ti	transfer RNA (m(1)G(37)) methyltransferase activity|tRNA-(N(1)G37) methyltransferase activity|tRNA (m(1)G(37)) methyltransferase activity											EC:2.1.1.228|RHEA:36899|MetaCyc:RXN-12458		molecular_function											owl:Class	
GO:0042082	biolink:NamedThing	GSI anchor biosynthetic process	The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.	got7fsn_ti	GPI/GSI anchor biosynthesis|GSI anchor anabolism|GPI/GSI anchor biosynthetic process|GSI anchor synthesis|GSI anchor formation|GSI anchor biosynthesis													biological_process											owl:Class	
GO:0102643	biolink:NamedThing	scalarane-17alpha-19-diol synthase activity	Catalysis of the reaction: scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O.	got7fsn_ti												MetaCyc:RXN-15755		molecular_function											owl:Class	
GO:0061502	biolink:NamedThing	early endosome to recycling endosome transport	The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes.	got7fsn_ti							dph	2013-01-04T07:24:56Z						biological_process											owl:Class	
GO:0043145	biolink:NamedThing	sno(s)RNA 3'-end cleavage	The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.	got7fsn_ti	sRNA 3'-end cleavage|snoRNA 3'-end cleavage|sno(s)RNA 3' end cleavage	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0090502	biolink:NamedThing	RNA phosphodiester bond hydrolysis, endonucleolytic	The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.	got7fsn_ti							tb	2012-10-22T12:05:27Z						biological_process											owl:Class	
GO:1990259	biolink:NamedThing	histone-glutamine methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-glutamine = S-adenosyl-L-homocysteine + (histone)-N5-methyl-glutamine.	got7fsn_ti							sp	2014-01-02T15:10:29Z						molecular_function											owl:Class	
GO:0043767	biolink:NamedThing	pyrrolysyl-tRNA synthetase activity	Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl).	got7fsn_ti	PylRS|pyrrolysine-tRNA ligase activity											RHEA:19277|EC:6.1.1.26|MetaCyc:6.1.1.26-RXN		molecular_function											owl:Class	
GO:0005846	biolink:NamedThing	nuclear cap binding complex	A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export.	got7fsn_ti	snRNA cap binding complex|NCBP-NIP1 complex|mRNA cap binding complex|CBC				Note that this complex can be found in the cytoplasm as well as the nucleus.									cellular_component											owl:Class	
GO:0061720	biolink:NamedThing	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).	got7fsn_ti							dph	2015-07-01T08:47:30Z						biological_process											owl:Class	
GO:1902777	biolink:NamedThing	6-sulfoquinovose(1-) catabolic process	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-).	got7fsn_ti	6-sulfoquinovose(1-) degradation|6-sulfoquinovose(1-) breakdown|6-sulfoquinovose(1-) catabolism						dph	2014-03-18T17:46:03Z						biological_process											owl:Class	
GO:0098822	biolink:NamedThing	peptidyl-cysteine modification to L-cysteine persulfide	The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide.	got7fsn_ti												RESID:AA0269		biological_process											owl:Class	
GO:0035496	biolink:NamedThing	lipopolysaccharide-1,5-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide.	got7fsn_ti	UDP-D-galactose:(glucosyl)lipopolysaccharide-1,5-D-galactosyltransferase|LPS-1,5-galactosyltransferase activity						bf	2010-04-26T03:00:21Z						molecular_function											owl:Class	
GO:0019825	biolink:NamedThing	oxygen binding	Binding to oxygen (O2).	got7fsn_ti	cytochrome P450|cytochrome P450 activity													molecular_function											owl:Class	
GO:0000298	biolink:NamedThing	endopolyphosphatase activity	Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues.	got7fsn_ti	polyphosphate polyphosphohydrolase activity|polyphosphate depolymerase activity|polyphosphatase activity|metaphosphatase activity|polymetaphosphatase activity											RHEA:22452|MetaCyc:ENDOPOLYPHOSPHATASE-RXN|EC:3.6.1.10		molecular_function											owl:Class	
GO:0102569	biolink:NamedThing	FR-33289 synthase activity	Catalysis of the reaction: FR-900098 + 2-oxoglutarate(2-) + O2 <=> FR-33289 + succinate(2-) + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-15082		molecular_function											owl:Class	
GO:0018389	biolink:NamedThing	N-terminal peptidyl-valine deamination	The deamination of the N-terminal valine residue of a protein to form isobutyrate.	got7fsn_ti														biological_process											owl:Class	
GO:0030419	biolink:NamedThing	nicotianamine catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.	got7fsn_ti	nicotianamine degradation|nicotianamine catabolism|nicotianamine breakdown													biological_process											owl:Class	
GO:0022828	biolink:NamedThing	phosphorylation-gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0002453	biolink:NamedThing	peripheral B cell anergy	Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells.	got7fsn_ti	peripheral B-lymphocyte anergy|peripheral B lymphocyte anergy|peripheral B-cell anergy													biological_process											owl:Class	
GO:0002515	biolink:NamedThing	B cell anergy	Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.	got7fsn_ti	B-cell anergy|B-lymphocyte anergy|B lymphocyte anergy													biological_process											owl:Class	
GO:0021681	biolink:NamedThing	cerebellar granular layer development	The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	got7fsn_ti														biological_process											owl:Class	
GO:0030252	biolink:NamedThing	growth hormone secretion	The regulated release of growth hormone from secretory granules into the blood.	got7fsn_ti	somatotropin secretion													biological_process											owl:Class	
GO:0033968	biolink:NamedThing	glutaryl-7-aminocephalosporanic-acid acylase activity	Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate.	got7fsn_ti	glutaryl-7-aminocephalosporanic acid acylase activity|(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase activity|glutaryl-7-ACA acylase activity|GCA|CA|GA|GL-7-ACA acylase activity|cephalosporin C acylase activity|7beta-(4-carboxybutanamido)cephalosporanic acid acylase activity|cephalosporin acylase activity											RHEA:23508|MetaCyc:3.5.1.93-RXN|EC:3.5.1.93		molecular_function											owl:Class	
GO:0008876	biolink:NamedThing	quinoprotein glucose dehydrogenase activity	Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol.	got7fsn_ti	glucose dehydrogenase (pyrroloquinoline-quinone) activity|D-glucose:ubiquinone oxidoreductase activity|quinoprotein D-glucose dehydrogenase activity|glucose dehydrogenase (PQQ-dependent) activity|D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase activity				Formerly EC:1.1.99.17.							EC:1.1.5.2|MetaCyc:GLUCDEHYDROG-RXN|RHEA:22152		molecular_function											owl:Class	
GO:0007136	biolink:NamedThing	meiotic prophase II	The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0001161	biolink:NamedThing	intronic transcription regulatory region sequence-specific DNA binding	Binding to an intronic DNA sequence that regulates the transcription of the transcript it is contained within.	got7fsn_ti	intronic transcription regulatory region DNA binding	https://github.com/geneontology/go-ontology/issues/19312			To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2011-01-28T03:44:02Z			GO:0044213			molecular_function											owl:Class	
GO:0034222	biolink:NamedThing	regulation of cell wall chitin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.	got7fsn_ti	regulation of cell wall chitin metabolism													biological_process											owl:Class	
GO:0018734	biolink:NamedThing	butyrolactone hydrolase activity	Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate.	got7fsn_ti												UM-BBD_reactionID:r0016		molecular_function											owl:Class	
GO:0071087	biolink:NamedThing	alpha11-beta1 integrin-collagen type I complex	A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen.	got7fsn_ti	ITGA11-ITGB1-COL1A1 complex						mah	2009-11-06T04:45:27Z						cellular_component											owl:Class	
GO:0046835	biolink:NamedThing	carbohydrate phosphorylation	The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y.	got7fsn_ti														biological_process											owl:Class	
GO:0007475	biolink:NamedThing	apposition of dorsal and ventral imaginal disc-derived wing surfaces	The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.	got7fsn_ti	apposition of dorsal and ventral wing surfaces													biological_process											owl:Class	
GO:0009635	biolink:NamedThing	response to herbicide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.	got7fsn_ti	herbicide susceptibility/resistance													biological_process											owl:Class	
GO:0047633	biolink:NamedThing	agmatine kinase activity	Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H(+).	got7fsn_ti	phosphagen phosphokinase activity|ATP:agmatine 4-N-phosphotransferase activity|ATP:agmatine N4-phosphotransferase activity											EC:2.7.3.10|RHEA:15953|MetaCyc:AGMATINE-KINASE-RXN|KEGG_REACTION:R01417		molecular_function											owl:Class	
GO:0032453	biolink:NamedThing	histone H3-methyl-lysine-4 demethylase activity	Catalysis of the removal of a methyl group from a modified lysine residue at position 4 of the histone H3 protein.	got7fsn_ti	histone H3K4 demethylase activity|histone demethylase activity (H3-K4 specific)	https://github.com/geneontology/go-ontology/issues/21089												molecular_function											owl:Class	
GO:0102224	biolink:NamedThing	GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity	Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+.	got7fsn_ti												RHEA:46316|MetaCyc:RXN-12236		molecular_function											owl:Class	
GO:0072277	biolink:NamedThing	metanephric glomerular capillary formation	The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti							mah	2010-04-01T02:47:56Z						biological_process											owl:Class	
GO:0072104	biolink:NamedThing	glomerular capillary formation	The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti							mah	2010-02-10T02:40:40Z						biological_process											owl:Class	
GO:0031876	biolink:NamedThing	secretin receptor binding	Binding to a secretin receptor.	got7fsn_ti	secretin receptor ligand													molecular_function											owl:Class	
GO:0016942	biolink:NamedThing	insulin-like growth factor binding protein complex	A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development.	got7fsn_ti	IGF binding protein complex													cellular_component											owl:Class	
GO:0036454	biolink:NamedThing	growth factor complex	A protein complex that has growth factor activity.	got7fsn_ti							bf	2013-11-07T11:27:16Z						cellular_component											owl:Class	
GO:0090432	biolink:NamedThing	myristoyl-CoA ligase activity	Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA.	got7fsn_ti	myristoyl-CoA synthetase activity						tb	2012-07-25T03:31:31Z						molecular_function											owl:Class	
GO:0018695	biolink:NamedThing	4-cresol dehydrogenase (hydroxylating) activity	Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.	got7fsn_ti	p-cresol methylhydroxylase activity|4-cresol dehydrogenase activity|p-cresol-(acceptor) oxidoreductase (hydroxylating) activity|4-cresol:acceptor oxidoreductase (methyl-hydroxylating)											UM-BBD_reactionID:r0272|EC:1.17.9.1|MetaCyc:1.17.99.1-RXN|RHEA:15141		molecular_function											owl:Class	
GO:0002389	biolink:NamedThing	tolerance induction in Peyer's patch	Tolerance induction taking place in the Peyer's patches.	got7fsn_ti														biological_process											owl:Class	
GO:0030274	biolink:NamedThing	LIM domain binding	Binding to a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.	got7fsn_ti														molecular_function											owl:Class	
GO:0033736	biolink:NamedThing	L-lysine 6-oxidase activity	Catalysis of the reaction: L-lysine + H(2)O + O(2) = allysine + H(2)O(2) + NH(4)(+).	got7fsn_ti	marinocine|L-lysine-epsilon-oxidase activity|L-lysine:oxygen 6-oxidoreductase (deaminating) activity|LodA|Lod											RHEA:22548|EC:1.4.3.20|KEGG_REACTION:R07598|MetaCyc:1.4.3.20-RXN		molecular_function											owl:Class	
GO:0098778	biolink:NamedThing	curli subunit secretion coupled to curli assembly	The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface.	got7fsn_ti	extracellular nucleation-precipitation pathway													biological_process											owl:Class	
GO:0005952	biolink:NamedThing	cAMP-dependent protein kinase complex	An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.	got7fsn_ti	PKA|adenosine 3',5'-cyclophosphate-dependent protein kinase complex|3',5'-cAMP-dependent protein kinase complex|cyclic AMP-dependent protein kinase complex|3',5' cAMP-dependent protein kinase complex													cellular_component											owl:Class	
GO:0070500	biolink:NamedThing	poly-gamma-glutamate metabolic process	The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.	got7fsn_ti	poly-gamma-glutamate metabolism													biological_process											owl:Class	
GO:0051722	biolink:NamedThing	protein C-terminal methylesterase activity	Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.	got7fsn_ti	protein phosphatase methylesterase activity											Reactome:R-HSA-8856951		molecular_function											owl:Class	
GO:0060319	biolink:NamedThing	primitive erythrocyte differentiation	Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.	got7fsn_ti	primitive erythropoiesis|primitive RBC differentiation|primitive red blood cell differentiation													biological_process											owl:Class	
GO:0072075	biolink:NamedThing	metanephric mesenchyme development	The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.	got7fsn_ti							mah	2010-01-25T04:40:11Z						biological_process											owl:Class	
GO:0008043	biolink:NamedThing	intracellular ferritin complex	A ferritin complex located in the cell. Intracellular ferritin complexes contain 24 subunits, in a mixture of L (light) chains and H (heavy) chains.	got7fsn_ti														cellular_component											owl:Class	
GO:0070288	biolink:NamedThing	ferritin complex	A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain.	got7fsn_ti														cellular_component											owl:Class	
GO:0008285	biolink:NamedThing	negative regulation of cell population proliferation	Any process that stops, prevents or reduces the rate or extent of cell proliferation.	got7fsn_ti	down regulation of cell proliferation|negative regulation of cell proliferation|downregulation of cell proliferation|inhibition of cell proliferation|down-regulation of cell proliferation													biological_process											owl:Class	
GO:0043369	biolink:NamedThing	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.	got7fsn_ti	CD4-positive or CD8-positive, alpha-beta T-lymphocyte lineage commitment|CD4-positive or CD8-positive, alpha-beta T lymphocyte lineage commitment|CD4-positive or CD8-positive, alpha-beta T-cell lineage commitment|CD4-positive/CD8-positive, alpha-beta T cell lineage commitment													biological_process											owl:Class	
GO:0010669	biolink:NamedThing	epithelial structure maintenance	A tissue homeostatic process required for the maintenance of epithelial structure.	got7fsn_ti														biological_process											owl:Class	
GO:0006883	biolink:NamedThing	cellular sodium ion homeostasis	Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0030004	biolink:NamedThing	cellular monovalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0002312	biolink:NamedThing	B cell activation involved in immune response	The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti	B cell activation during immune response|B lymphocyte activation during immune response|B-cell activation during immune response|B-lymphocyte activation during immune response													biological_process											owl:Class	
GO:0002285	biolink:NamedThing	lymphocyte activation involved in immune response	A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	lymphocyte activation during immune response													biological_process											owl:Class	
GO:0019249	biolink:NamedThing	lactate biosynthetic process	The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid.	got7fsn_ti	lactate formation|lactate biosynthesis|lactate synthesis|lactate anabolism													biological_process											owl:Class	
GO:0000434	biolink:NamedThing	carbon catabolite repression of transcription from RNA polymerase II promoter by galactose	Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.	got7fsn_ti	inhibition of transcription from RNA polymerase II promoter by galactose|down-regulation of transcription from RNA polymerase II promoter by galactose|downregulation of transcription from RNA polymerase II promoter by galactose|down regulation of transcription from RNA polymerase II promoter by galactose													biological_process											owl:Class	
GO:0000437	biolink:NamedThing	carbon catabolite repression of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter by carbon catabolites													biological_process											owl:Class	
GO:0019395	biolink:NamedThing	fatty acid oxidation	The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.	got7fsn_ti												MetaCyc:FAO-PWY		biological_process											owl:Class	
GO:0006631	biolink:NamedThing	fatty acid metabolic process	The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.	got7fsn_ti	fatty acid metabolism											Wikipedia:Fatty_acid_metabolism		biological_process											owl:Class	
GO:0018563	biolink:NamedThing	2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate.	got7fsn_ti												UM-BBD_reactionID:r0310|EC:1.13.11.-		molecular_function											owl:Class	
GO:0042069	biolink:NamedThing	regulation of catecholamine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.	got7fsn_ti	regulation of catecholamine metabolism													biological_process											owl:Class	
GO:0102860	biolink:NamedThing	1-18:1-2-18:2-phosphatidylcholine synthase activity	Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:1-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8327|EC:1.14.19.22		molecular_function											owl:Class	
GO:0032145	biolink:NamedThing	succinate-semialdehyde dehydrogenase binding	Binding to succinate-semialdehyde dehydrogenase.	got7fsn_ti	succinic semialdehyde dehydrogenase binding													molecular_function											owl:Class	
GO:0080154	biolink:NamedThing	regulation of fertilization	Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).	got7fsn_ti							dhl	2010-09-01T03:44:27Z						biological_process											owl:Class	
GO:0002683	biolink:NamedThing	negative regulation of immune system process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.	got7fsn_ti	inhibition of immune system process|down regulation of immune system process|downregulation of immune system process|down-regulation of immune system process													biological_process											owl:Class	
GO:0042857	biolink:NamedThing	chrysobactin metabolic process	The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).	got7fsn_ti	chrysobactin metabolism													biological_process											owl:Class	
GO:0031676	biolink:NamedThing	plasma membrane-derived thylakoid membrane	The pigmented membrane of a plasma membrane-derived thylakoid.	got7fsn_ti	plasma membrane thylakoid membrane													cellular_component											owl:Class	
GO:0042651	biolink:NamedThing	thylakoid membrane	The pigmented membrane of any thylakoid.	got7fsn_ti														cellular_component											owl:Class	
GO:0018101	biolink:NamedThing	protein citrullination	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline.	got7fsn_ti	peptidyl-citrulline synthesis from peptidyl-arginine|deimination|peptidyl-citrulline biosynthetic process from peptidyl-arginine|peptidyl-citrulline anabolism from peptidyl-arginine|peptidyl-citrulline formation from peptidyl-arginine				Citrullination is distinct from the formation of the free amino acid citrulline (e.g. as part of the urea cycle).							RESID:AA0214		biological_process											owl:Class	
GO:0021779	biolink:NamedThing	oligodendrocyte cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.	got7fsn_ti														biological_process											owl:Class	
GO:0034951	biolink:NamedThing	o-hydroxylaminobenzoate mutase activity	Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate.	got7fsn_ti												MetaCyc:RXN-8846|UM-BBD_reactionID:r1026|EC:5.4.99.-		molecular_function											owl:Class	
GO:0061371	biolink:NamedThing	determination of heart left/right asymmetry	Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.	got7fsn_ti	determination of cardiac left/right asymmetry						dph	2010-11-03T02:13:58Z						biological_process											owl:Class	
GO:0001999	biolink:NamedThing	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	The physiological response of the kidneys to a decrease in blood flow.	got7fsn_ti	renal response to blood flow during renin-angiotensin control of blood pressure													biological_process											owl:Class	
GO:0033856	biolink:NamedThing	pyridoxine 5'-phosphate synthase activity	Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate.	got7fsn_ti	PNP synthase activity|pyridoxine 5-phosphate phospho lyase activity|1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing) activity											RHEA:15265|EC:2.6.99.2|MetaCyc:PDXJ-RXN|KEGG_REACTION:R05838		molecular_function											owl:Class	
GO:0016769	biolink:NamedThing	transferase activity, transferring nitrogenous groups	Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring other nitrogenous groups											EC:2.6.-.-		molecular_function											owl:Class	
GO:0033432	biolink:NamedThing	CGG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CGG codon.	got7fsn_ti	arginine tRNA				Note that in the standard genetic code, CGG codes for arginine.									molecular_function											owl:Class	
GO:0044487	biolink:NamedThing	envenomation resulting in modulation of transmission of nerve impulse in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism.	got7fsn_ti	envenomation resulting in modulation of conduction of nerve impulse in other organism						jl	2012-01-26T05:01:54Z						biological_process											owl:Class	
GO:0033540	biolink:NamedThing	fatty acid beta-oxidation using acyl-CoA oxidase	A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	got7fsn_ti												MetaCyc:PWY-5136		biological_process											owl:Class	
GO:0046150	biolink:NamedThing	melanin catabolic process	The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.	got7fsn_ti	melanin catabolism|melanin breakdown|melanin degradation													biological_process											owl:Class	
GO:0017071	biolink:NamedThing	intracellular cyclic nucleotide activated cation channel complex	A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts.	got7fsn_ti														cellular_component											owl:Class	
GO:0035142	biolink:NamedThing	dorsal fin morphogenesis	The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.	got7fsn_ti														biological_process											owl:Class	
GO:0043969	biolink:NamedThing	histone H2B acetylation	The modification of histone H2B by the addition of an acetyl group.	got7fsn_ti														biological_process											owl:Class	
GO:0016573	biolink:NamedThing	histone acetylation	The modification of a histone by the addition of an acetyl group.	got7fsn_ti														biological_process											owl:Class	
GO:0071786	biolink:NamedThing	endoplasmic reticulum tubular network organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.	got7fsn_ti	ER tubular network organisation|ER tubular network organization|endoplasmic reticulum tubular network organisation						mah	2010-09-01T01:53:51Z						biological_process											owl:Class	
GO:0019655	biolink:NamedThing	glycolytic fermentation to ethanol	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.	got7fsn_ti	ethanol fermentation|alcoholic fermentation|glucose fermentation to ethanol|glucose catabolic process to ethanol											Wikipedia:Ethanol_fermentation		biological_process											owl:Class	
GO:1990794	biolink:NamedThing	basolateral part of cell	The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells.	got7fsn_ti							sl	2015-07-09T20:31:50Z						cellular_component											owl:Class	
GO:0002408	biolink:NamedThing	myeloid dendritic cell chemotaxis	The movement of a myeloid dendritic cell in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0002407	biolink:NamedThing	dendritic cell chemotaxis	The movement of a dendritic cell in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0004061	biolink:NamedThing	arylformamidase activity	Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.	got7fsn_ti	formamidase II|kynurenine formamidase activity|formylase activity|aryl-formylamine amidohydrolase activity|formylkynureninase activity|formylkynurenine formamidase activity|formamidase I											EC:3.5.1.9|MetaCyc:ARYLFORMAMIDASE-RXN|Reactome:R-HSA-71189|RHEA:13009		molecular_function											owl:Class	
GO:0004055	biolink:NamedThing	argininosuccinate synthase activity	Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.	got7fsn_ti	arginine succinate synthetase activity|arginosuccinate synthetase activity|argininosuccinic acid synthetase activity|L-citrulline:L-aspartate ligase (AMP-forming)|argininosuccinate synthetase activity|citrulline--aspartate ligase activity											RHEA:10932|Reactome:R-HSA-70577|EC:6.3.4.5|MetaCyc:ARGSUCCINSYN-RXN		molecular_function											owl:Class	
GO:0021600	biolink:NamedThing	abducens nerve structural organization	The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	got7fsn_ti	abducens nerve structural organisation|CN VI structural organization													biological_process											owl:Class	
GO:0043482	biolink:NamedThing	cellular pigment accumulation	The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0001677	biolink:NamedThing	formation of translation initiation ternary complex	Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).	got7fsn_ti	translation initiation ternary complex assembly													biological_process											owl:Class	
GO:0002165	biolink:NamedThing	instar larval or pupal development	The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0019465	biolink:NamedThing	aspartate transamidation	The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group.	got7fsn_ti												MetaCyc:ASPARTATE-DEG1-PWY|MetaCyc:ASPARTATESYN-PWY		biological_process											owl:Class	
GO:0006533	biolink:NamedThing	aspartate catabolic process	The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.	got7fsn_ti	aspartate catabolism|aspartate degradation|aspartate breakdown													biological_process											owl:Class	
GO:0003408	biolink:NamedThing	optic cup formation involved in camera-type eye development	The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle.	got7fsn_ti							dph	2009-12-21T02:37:12Z						biological_process											owl:Class	
GO:0042324	biolink:NamedThing	hypocretin receptor binding	Binding to a hypocretin receptor.	got7fsn_ti	orexin receptor binding|hypocretin receptor ligand|orexin receptor ligand													molecular_function											owl:Class	
GO:0070258	biolink:NamedThing	inner membrane pellicle complex	A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell.	got7fsn_ti	inner membrane complex													cellular_component											owl:Class	
GO:0071964	biolink:NamedThing	establishment of cell polarity regulating cell shape	Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell.	got7fsn_ti							mah	2011-06-22T03:10:08Z						biological_process											owl:Class	
GO:0106223	biolink:NamedThing	germacrene A hydroxylase activity	Catalysis of the reaction:(+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].	got7fsn_ti	germacrene A alcohol dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.1.1.314.		hjd	2019-09-06T16:36:25Z			GO:0102260	EC:1.14.14.95|RHEA:30303|MetaCyc:RXN-12449		molecular_function											owl:Class	
GO:0032041	biolink:NamedThing	NAD-dependent histone deacetylase activity (H3-K14 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.	got7fsn_ti												EC:3.5.1.98		molecular_function											owl:Class	
GO:0017136	biolink:NamedThing	NAD-dependent histone deacetylase activity	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.	got7fsn_ti	SIR2													molecular_function											owl:Class	
GO:0034870	biolink:NamedThing	pinacolone 5-monooxygenase activity	Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one.	got7fsn_ti												UM-BBD_reactionID:r12979		molecular_function											owl:Class	
GO:0047404	biolink:NamedThing	glucuronosyl-disulfoglucosamine glucuronidase activity	Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine.	got7fsn_ti	glucuronosyl-disulphoglucosamine glucuronidase activity|3-D-glucuronsyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase activity|3-D-glucuronsyl-2-N,6-disulfo-beta-D-glucosamine glucuronohydrolase activity											RHEA:15073|EC:3.2.1.56|MetaCyc:3.2.1.56-RXN		molecular_function											owl:Class	
GO:0051744	biolink:NamedThing	3,8-divinyl protochlorophyllide a 8-vinyl reductase activity	Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+.	got7fsn_ti												RHEA:48884|MetaCyc:RXN1F-72		molecular_function											owl:Class	
GO:0050354	biolink:NamedThing	triokinase activity	Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+).	got7fsn_ti	ATP:D-glyceraldehyde 3-phosphotransferase activity|triose kinase activity|D-triokinase activity|trio triose kinase (phosphorylating)											Reactome:R-HSA-70349|RHEA:13941|EC:2.7.1.28|MetaCyc:TRIOKINASE-RXN|KEGG_REACTION:R01059		molecular_function											owl:Class	
GO:0033773	biolink:NamedThing	isoflavone 2'-hydroxylase activity	Catalysis of the reaction: an isoflavone + O2 + reduced [NADPH-hemoprotein reductase] = a 2'-hydroxyisoflavone + H+ + H2O + oxidized [NADPH-hemoprotein reductase].	got7fsn_ti	CYP81E1|CYP Ge-3|isoflavone 2'-monooxygenase activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.14.13.89.							MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN|RHEA:18849|EC:1.14.14.90		molecular_function											owl:Class	
GO:0004072	biolink:NamedThing	aspartate kinase activity	Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+).	got7fsn_ti	beta-aspartokinase activity|ATP:L-aspartate 4-phosphotransferase activity|aspartokinase activity|aspartic kinase activity											KEGG_REACTION:R00480|MetaCyc:ASPARTATEKIN-RXN|EC:2.7.2.4|RHEA:23776		molecular_function											owl:Class	
GO:0047124	biolink:NamedThing	L-erythro-3,5-diaminohexanoate dehydrogenase activity	Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H(2)O + NAD(+) = (S)-5-amino-3-oxo-hexanoate + H(+) + NADH + NH(4)(+).	got7fsn_ti	L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)|L-3,5-diaminohexanoate dehydrogenase activity											EC:1.4.1.11|MetaCyc:1.4.1.11-RXN|KEGG_REACTION:R03349|RHEA:19633		molecular_function											owl:Class	
GO:0010451	biolink:NamedThing	floral meristem growth	The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower.	got7fsn_ti														biological_process											owl:Class	
GO:0060291	biolink:NamedThing	long-term synaptic potentiation	A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.	got7fsn_ti	LTP|long-term potentiation													biological_process											owl:Class	
GO:0098731	biolink:NamedThing	skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration	Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells.	got7fsn_ti														biological_process											owl:Class	
GO:0032386	biolink:NamedThing	regulation of intracellular transport	Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.	got7fsn_ti														biological_process											owl:Class	
GO:0103090	biolink:NamedThing	methylthiohexylmalate dehydrogenase activity	Catalysis of the reaction: 3-(6'-methylthio)hexylmalate <=> H+ + 2-oxo-9-methylthiononanoate + carbon dioxide.	got7fsn_ti												MetaCyc:RXNQT-4174		molecular_function											owl:Class	
GO:0005687	biolink:NamedThing	U4 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U4, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4 snRNP, most of which remain associated with the U4 snRNA both while the U4 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.	got7fsn_ti	snRNP U4													cellular_component											owl:Class	
GO:0006892	biolink:NamedThing	post-Golgi vesicle-mediated transport	The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.	got7fsn_ti	post-Golgi transport													biological_process											owl:Class	
GO:0014729	biolink:NamedThing	regulation of the velocity of shortening of skeletal muscle modulating contraction	Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres.	got7fsn_ti	regulation of the velocity of shortening of skeletal muscle during contraction													biological_process											owl:Class	
GO:0033269	biolink:NamedThing	internode region of axon	An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath.	got7fsn_ti	internode											NIF_Subcellular:sao206157942		cellular_component											owl:Class	
GO:0047001	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity	Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate.	got7fsn_ti	2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase activity|2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase activity|2-keto-3-deoxygluconate dehydrogenase activity|2-keto-3-deoxygluconate 5-dehydrogenase activity|2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity											MetaCyc:1.1.1.127-RXN|EC:1.1.1.127|RHEA:24232		molecular_function											owl:Class	
GO:0102887	biolink:NamedThing	beta-sesquiphellandrene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-sesquiphellandrene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8430|EC:4.2.3.123|RHEA:32699		molecular_function											owl:Class	
GO:0070120	biolink:NamedThing	ciliary neurotrophic factor-mediated signaling pathway	A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	ciliary neurotrophic factor-mediated signalling pathway|CNTF-mediated signaling pathway													biological_process											owl:Class	
GO:0047310	biolink:NamedThing	glutamine-scyllo-inositol transaminase activity	Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate.	got7fsn_ti	glutamine--scyllo-inosose aminotransferase activity|glutamine-scyllo-inosose transaminase activity|glutamine-scyllo-inosose aminotransferase activity|glutamine scyllo-inosose aminotransferase activity|glutamine--scyllo-inosose transaminase activity|L-glutamine-keto-scyllo-inositol aminotransferase activity|L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase activity|L-glutamine-scyllo-inosose transaminase activity											KEGG_REACTION:R02781|RHEA:22920|EC:2.6.1.50|MetaCyc:2.6.1.50-RXN		molecular_function											owl:Class	
GO:0002253	biolink:NamedThing	activation of immune response	Any process that initiates an immune response.	got7fsn_ti														biological_process											owl:Class	
GO:0060749	biolink:NamedThing	mammary gland alveolus development	The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.	got7fsn_ti							dph	2009-06-22T10:52:12Z						biological_process											owl:Class	
GO:0090378	biolink:NamedThing	seed trichome elongation	The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.	got7fsn_ti					The increase in length of the seed trichome without cell division. Elongation is defined to be from 5 to 20 DPA in Gossypium spp.		tb	2010-09-15T02:20:47Z						biological_process											owl:Class	
GO:0015882	biolink:NamedThing	L-ascorbic acid transmembrane transport	The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.	got7fsn_ti	vitamin C transport|L-ascorbate transport|L-ascorbic acid transport													biological_process											owl:Class	
GO:0106375	biolink:NamedThing	deoxynucleoside triphosphate hydrolase activity	Catalysis of the reaction:  dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate.	got7fsn_ti							hjd	2021-04-15T20:44:33Z				RHEA:46148		molecular_function											owl:Class	
GO:0016793	biolink:NamedThing	triphosphoric monoester hydrolase activity	Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.	got7fsn_ti												EC:3.1.5.-|Reactome:R-HSA-8866601		molecular_function											owl:Class	
GO:0080182	biolink:NamedThing	histone H3-K4 trimethylation	The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone.	got7fsn_ti							dhl	2011-08-10T04:18:36Z						biological_process											owl:Class	
GO:0009439	biolink:NamedThing	cyanate metabolic process	The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid.	got7fsn_ti	cyanate metabolism											MetaCyc:CYANCAT-PWY		biological_process											owl:Class	
GO:0008020	biolink:NamedThing	G protein-coupled photoreceptor activity	Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G protein coupled photoreceptor activity|G-protein coupled photoreceptor activity|photoreceptor activity, G-protein coupled										GO:0004975			molecular_function											owl:Class	
GO:0097612	biolink:NamedThing	dinoflagellate sulcus	A cell surface furrow that occurs on the ventral side of a dinoflagellate cell. It partially houses the longitudinal flagellum. The sulcus intersects with the cingulum on the ventral side of a dinoflagellate cell.	got7fsn_ti	longitudinal furrow|longitudinal groove|sulcus				The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. Also, the ventral (front) side of a dinoflagellate cell is the one where the sulcus is located (as opposed to the dorsal (back) side).		pr	2014-06-09T11:31:05Z						cellular_component											owl:Class	
GO:0035995	biolink:NamedThing	detection of muscle stretch	The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti							bf	2011-08-30T01:53:35Z						biological_process											owl:Class	
GO:0042797	biolink:NamedThing	tRNA transcription by RNA polymerase III	The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.	got7fsn_ti	tRNA transcription from Pol III promoter|tRNA transcription from RNA polymerase III promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0006383	biolink:NamedThing	transcription by RNA polymerase III	The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.	got7fsn_ti	transcription from RNA polymerase III type 3 promoter|transcription from RNA polymerase III type 2 promoter|transcription from Pol III promoter|transcription from RNA polymerase III promoter|U6 snRNA transcription (mammalian)|U2 snRNA transcription (S. cerevisiae)|transcription from a RNA polymerase III hybrid type promoter|RNA polymerase III transcription factor activity	https://github.com/geneontology/go-ontology/issues/14854|https://github.com/geneontology/go-ontology/issues/9617					krc	2010-08-18T06:37:56Z			GO:0001035|GO:0001009|GO:0001041			biological_process											owl:Class	
GO:0045519	biolink:NamedThing	interleukin-23 receptor binding	Binding to an interleukin-23 receptor.	got7fsn_ti	interleukin-23 receptor ligand|IL-23													molecular_function											owl:Class	
GO:0021664	biolink:NamedThing	rhombomere 5 morphogenesis	The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0047696	biolink:NamedThing	beta-adrenergic receptor kinase activity	Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor.	got7fsn_ti	beta-adrenergic receptor-specific kinase activity|GRK2|adrenergic receptor kinase activity|STK15|BARK1|betaARK1|beta2ARK|beta-adrenergic-receptor kinase activity|beta-ARK 1|beta-adrenoceptor kinase activity|beta-adrenoceptor kinase 2 activity|beta-adrenergic-receptor kinase (phosphorylating) activity|beta-AR kinase activity|beta-adrenoceptor kinase 1 activity|beta-receptor kinase activity|[b-adrenergic-receptor] kinase activity|ADRBK1|beta-ARK 2|ATP:beta-adrenergic-receptor phosphotransferase activity|GRK3|beta-ARK											RHEA:19429|EC:2.7.11.15|Reactome:R-HSA-8866268|Reactome:R-HSA-8851797		molecular_function											owl:Class	
GO:0021764	biolink:NamedThing	amygdala development	The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.	got7fsn_ti														biological_process											owl:Class	
GO:0031972	biolink:NamedThing	chloroplast intermembrane space	The region between the inner and outer lipid bilayers of a chloroplast envelope.	got7fsn_ti	chloroplast envelope lumen													cellular_component											owl:Class	
GO:0009529	biolink:NamedThing	plastid intermembrane space	The region between the inner and outer lipid bilayers of the plastid envelope.	got7fsn_ti	plastid envelope lumen													cellular_component											owl:Class	
GO:0102507	biolink:NamedThing	cyanidin 3-O-glucoside 7-O-glucosyltransferase (hydroxybenzoly-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + 4-hydroxybenzoic acid + H+.	got7fsn_ti												MetaCyc:RXN-14434|EC:2.4.1.300		molecular_function											owl:Class	
GO:0030099	biolink:NamedThing	myeloid cell differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.	got7fsn_ti														biological_process											owl:Class	
GO:0102147	biolink:NamedThing	3'-O-methyltricetin O methyl transferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine  + 3',5'-di-O-methyltricetin.	got7fsn_ti												RHEA:27497|MetaCyc:RXN-11583		molecular_function											owl:Class	
GO:0003945	biolink:NamedThing	N-acetyllactosamine synthase activity	Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.	got7fsn_ti	acetyllactosamine synthetase activity|beta-N-acetylglucosaminide beta-1,4-galactosyltransferase activity|lactose synthetase A protein|beta-1,4-GalT|N-acetylglucosamine (beta-1,4)galactosyltransferase activity|UDP-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity|uridine diphosphogalactose-acetylglucosamine galactosyltransferase activity|UDPgalactose:N-acetylglucosaminyl(beta-1,4)galactosyltransferase activity|N-acetyllactosamine synthetase activity|UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase activity|UDP-galactose-N-acetylglucosamine galactosyltransferase activity|beta-1,4-galactosyltransferase activity|NAL synthetase activity|beta-(1,4)-galactosyltransferase activity|Gal-T|UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase activity|UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase activity|lactosamine synthetase activity|N-acetylglucosamine beta-(1,4)-galactosyltransferase activity|UDPgalactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity|UDP-beta-1,4-galactosyltransferase activity|UDP-Gal:N-acetylglucosamine beta-1,4-galactosyltransferase activity|UDP-galactose-acetylglucosamine galactosyltransferase activity|lactosamine synthase activity|UDP-galactose:N-acetylglucosaminide beta-1,4-galactosyltransferase activity|UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase activity											MetaCyc:N-ACETYLLACTOSAMINE-SYNTHASE-RXN|EC:2.4.1.90|RHEA:17745		molecular_function											owl:Class	
GO:0032267	biolink:NamedThing	tRNA(Ile)-lysidine synthase activity	Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine.	got7fsn_ti	tRNA(Ile)-2-lysyl-cytidine synthase activity|tRNA(Ile)-lysidine synthetase activity											EC:6.3.4.-		molecular_function											owl:Class	
GO:0080124	biolink:NamedThing	pheophytinase activity	Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide.	got7fsn_ti	pheophytin pheophorbide hydrolase activity						dhl	2009-04-28T04:16:11Z						molecular_function											owl:Class	
GO:0004831	biolink:NamedThing	tyrosine-tRNA ligase activity	Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+).	got7fsn_ti	L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity|tyrosine translase activity|tyrosine-transfer RNA ligase activity|tyrosyl-tRNA ligase activity|tyrosyl-tRNA synthetase activity|tyrosyl-transfer RNA synthetase activity|tyrosine-transfer ribonucleate synthetase activity|L-tyrosine-tRNATyr ligase (AMP-forming)|tyrosine tRNA synthetase activity|tyrosyl-transfer ribonucleic acid synthetase activity|tyrosyl-transfer ribonucleate synthetase activity|L-tyrosine:tRNATyr ligase (AMP-forming)											Reactome:R-HSA-379980|EC:6.1.1.1|RHEA:10220|Reactome:R-HSA-380170|MetaCyc:TYROSINE--TRNA-LIGASE-RXN|KEGG_REACTION:R02918		molecular_function											owl:Class	
GO:0060737	biolink:NamedThing	prostate gland morphogenetic growth	The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.	got7fsn_ti	prostate gland growth involved in morphogenesis						dph	2009-06-15T09:24:40Z						biological_process											owl:Class	
GO:0045515	biolink:NamedThing	interleukin-18 receptor binding	Binding to an interleukin-18 receptor.	got7fsn_ti	interleukin-18 receptor ligand|IL-18													molecular_function											owl:Class	
GO:0047648	biolink:NamedThing	alkylamidase activity	Catalysis of the reaction: N-methylhexanamide + H(2)O = hexanoate + methylammonium.	got7fsn_ti	N-methylhexanamide amidohydrolase activity											EC:3.5.1.39|KEGG_REACTION:R03620|RHEA:20081|MetaCyc:ALKYLAMIDASE-RXN		molecular_function											owl:Class	
GO:0007314	biolink:NamedThing	oocyte anterior/posterior axis specification	Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte anterior/posterior axis determination										GO:0048112			biological_process											owl:Class	
GO:0008265	biolink:NamedThing	Mo-molybdopterin cofactor sulfurase activity	Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase.	got7fsn_ti	molybdopterin synthase sulfurylase activity|Mo-molybdopterin cofactor sulphurase activity|molybdopterin cofactor sulfurase activity											EC:2.8.1.9|Reactome:R-HSA-947499		molecular_function											owl:Class	
GO:0017017	biolink:NamedThing	MAP kinase tyrosine/serine/threonine phosphatase activity	Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.	got7fsn_ti	dual-specificity MAP kinase phosphatase activity													molecular_function											owl:Class	
GO:0052112	biolink:NamedThing	occlusion by symbiont of host xylem	The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0052110	biolink:NamedThing	occlusion by symbiont of host vascular system	The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0071358	biolink:NamedThing	cellular response to type III interferon	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	cellular response to type III IFN|cellular response to interferon-lambda						mah	2009-12-11T02:52:00Z						biological_process											owl:Class	
GO:0039722	biolink:NamedThing	suppression by virus of host toll-like receptor signaling pathway	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism.	got7fsn_ti	inhibition of host TLR pathway by virus|suppression by virus of host TLR signaling pathway						bf	2014-01-06T11:39:58Z						biological_process											owl:Class	
GO:0071987	biolink:NamedThing	WD40-repeat domain binding	Binding to a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain.	got7fsn_ti	WD domain binding|beta-transducin repeat domain binding						mah	2010-10-22T02:53:29Z						molecular_function											owl:Class	
GO:0070645	biolink:NamedThing	Ubisch body	A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development.	got7fsn_ti	orbicule						mah	2009-05-11T11:35:33Z						cellular_component											owl:Class	
GO:0003855	biolink:NamedThing	3-dehydroquinate dehydratase activity	Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O.	got7fsn_ti	3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming)|dehydroquinate dehydratase activity|5-dehydroquinase activity|5-dehydroquinate dehydratase activity|5-dehydroquinate hydro-lyase activity|3-dehydroquinate hydro-lyase activity|3-dehydroquinate hydrolase activity|DHQase|3-dehydroquinase activity|dehydroquinase activity											EC:4.2.1.10|KEGG_REACTION:R03084|MetaCyc:3-DEHYDROQUINATE-DEHYDRATASE-RXN|RHEA:21096		molecular_function											owl:Class	
GO:2000643	biolink:NamedThing	positive regulation of early endosome to late endosome transport	Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport.	got7fsn_ti							vk	2011-04-21T11:20:09Z						biological_process											owl:Class	
GO:0048522	biolink:NamedThing	positive regulation of cellular process	Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	got7fsn_ti	up-regulation of cellular process|positive regulation of cellular physiological process|upregulation of cellular process|activation of cellular process|up regulation of cellular process|stimulation of cellular process										GO:0051242			biological_process											owl:Class	
GO:0048245	biolink:NamedThing	eosinophil chemotaxis	The movement of an eosinophil in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0006306	biolink:NamedThing	DNA methylation	The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.	got7fsn_ti												Wikipedia:DNA_methylation		biological_process											owl:Class	
GO:0030903	biolink:NamedThing	notochord development	The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.	got7fsn_ti														biological_process											owl:Class	
GO:0005230	biolink:NamedThing	extracellular ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0044198	biolink:NamedThing	zf-TRAF domain binding	Binding to a TRAF-type zinc finger domain of a protein.	got7fsn_ti	zinc finger TRAF-type domain binding|TRAF-type zinc finger domain binding|zinc-finger-TRAF domain binding						jl	2009-10-20T04:09:08Z						molecular_function											owl:Class	
GO:0038099	biolink:NamedThing	nodal receptor complex assembly	The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals).	got7fsn_ti	ActRIIB.ALK4.EGF-CFC complex formation|nodal receptor complex formation						bf	2012-02-17T11:16:40Z						biological_process											owl:Class	
GO:0060788	biolink:NamedThing	ectodermal placode formation	The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.	got7fsn_ti							dph	2009-08-04T12:15:57Z						biological_process											owl:Class	
GO:0061688	biolink:NamedThing	glycolytic process via Entner-Doudoroff Pathway	A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes.	got7fsn_ti	gluconate pathway						dph	2015-03-12T14:39:00Z						biological_process											owl:Class	
GO:0006096	biolink:NamedThing	glycolytic process	The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.	got7fsn_ti	Embden-Meyerhof-Parnas pathway|glycolysis|anaerobic glycolysis|modifed Embden-Meyerhof pathway|Embden-Meyerhof pathway										GO:0019641|GO:0019642	MetaCyc:GLYCOLYSIS-VARIANTS		biological_process											owl:Class	
GO:0140494	biolink:NamedThing	migrasome	A vesicular organelle that forms on retraction fibers behind migrating cells and mediates the release of cytoplasmic contents during cell migration.	got7fsn_ti							pg	2020-07-10T15:09:40Z						cellular_component											owl:Class	
GO:0008913	biolink:NamedThing	lauroyltransferase activity	Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another.	got7fsn_ti	lauroyl transferase activity													molecular_function											owl:Class	
GO:0097083	biolink:NamedThing	vascular associated smooth muscle cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	got7fsn_ti	vascular smooth muscle cell fate determination						pr	2011-06-20T04:00:28Z						biological_process											owl:Class	
GO:0007521	biolink:NamedThing	muscle cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0070515	biolink:NamedThing	alphaIIb-beta3 integrin-talin complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin.	got7fsn_ti	ITGA2b-ITGB3-TLN1 complex													cellular_component											owl:Class	
GO:0016749	biolink:NamedThing	N-succinyltransferase activity	Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0008972	biolink:NamedThing	phosphomethylpyrimidine kinase activity	Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine.	got7fsn_ti	hydroxymethylpyrimidine phosphokinase activity|ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase activity											EC:2.7.4.7|RHEA:19893|MetaCyc:PYRIMSYN3-RXN		molecular_function											owl:Class	
GO:0038164	biolink:NamedThing	thrombopoietin receptor activity	Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti							bf	2012-05-14T02:46:58Z						molecular_function											owl:Class	
GO:0052761	biolink:NamedThing	exo-1,4-beta-D-glucosaminidase activity	Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units.	got7fsn_ti	chitosan glucosaminohydrolase activity|exo-beta-D-glucosaminidase activity|exochitosanase activity|chitosan exo-1,4-beta-D-glucosaminidase activity						ai	2011-09-28T03:30:54Z				KEGG_REACTION:R08715|MetaCyc:3.2.1.165-RXN|EC:3.2.1.165		molecular_function											owl:Class	
GO:0061847	biolink:NamedThing	response to cholecystokinin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0043434	biolink:NamedThing	response to peptide hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.	got7fsn_ti	response to peptide hormone stimulus|response to polypeptide hormone stimulus													biological_process											owl:Class	
GO:0003957	biolink:NamedThing	NAD(P)+ transhydrogenase (B-specific) activity	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+, driving the transfer of a solute or solutes from one side of a membrane to the other. In the course of the reaction (left to right) one H atom is transferred from inside the cell to outside. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+.	got7fsn_ti	nicotinamide nucleotide transhydrogenase activity|NADH transhydrogenase|NADPH-NAD oxidoreductase|NADH-NADP-transhydrogenase|pyridine nucleotide transferase|non-energy-linked transhydrogenase activity|NAD(P) transhydrogenase (B-specific) activity|NADPH:NAD+ transhydrogenase|nicotinamide adenine dinucleotide (phosphate) transhydrogenase|H+-thase|NADPH-NAD transhydrogenase|NADPH:NAD+ oxidoreductase (B-specific)|pyridine nucleotide transhydrogenase activity|NAD transhydrogenase											MetaCyc:PYRNUTRANSHYDROGEN-RXN|EC:1.6.1.1		molecular_function											owl:Class	
GO:0015078	biolink:NamedThing	proton transmembrane transporter activity	Enables the transfer of a proton from one side of a membrane to the other.	got7fsn_ti	hydrogen ion transmembrane transporter activity|proton transporter activity											Reactome:R-HSA-917841|Reactome:R-HSA-74723|Reactome:R-HSA-164834|Reactome:R-HSA-170026|Reactome:R-HSA-1222516		molecular_function											owl:Class	
GO:0004514	biolink:NamedThing	nicotinate-nucleotide diphosphorylase (carboxylating) activity	Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.	got7fsn_ti	NAD pyrophosphorylase activity|quinolinic acid phosphoribosyltransferase activity|quinolinic phosphoribosyltransferase activity|nicotinate mononucleotide pyrophosphorylase (carboxylating)|nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)|quinolinate phosphoribosyltransferase (decarboxylating) activity|QAPRTase activity|nicotinate-nucleotide pyrophosphorylase (carboxylating) activity											RHEA:12733|Reactome:R-HSA-197268|KEGG_REACTION:R03348|EC:2.4.2.19|MetaCyc:QUINOPRIBOTRANS-RXN		molecular_function											owl:Class	
GO:0008586	biolink:NamedThing	imaginal disc-derived wing vein morphogenesis	The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.	got7fsn_ti	wing vein morphogenesis													biological_process											owl:Class	
GO:0072592	biolink:NamedThing	oxygen metabolic process	The chemical reactions and pathways involving diatomic oxygen (O2).	got7fsn_ti	oxygen metabolism|diatomic oxygen metabolic process						mah	2011-02-11T10:46:51Z						biological_process											owl:Class	
GO:0004372	biolink:NamedThing	glycine hydroxymethyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.	got7fsn_ti	serine transhydroxymethylase activity|serine aldolase activity|serine hydroxymethyltransferase activity|L-serine hydroxymethyltransferase activity|serine hydroxymethylase activity|5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity|allothreonine aldolase activity											Reactome:R-HSA-200651|RHEA:15481|Reactome:R-HSA-200735|Reactome:R-HSA-71249|Reactome:R-HSA-5694137|MetaCyc:GLYOHMETRANS-RXN|EC:2.1.2.1		molecular_function											owl:Class	
GO:0018105	biolink:NamedThing	peptidyl-serine phosphorylation	The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.	got7fsn_ti												RESID:AA0037		biological_process											owl:Class	
GO:0044185	biolink:NamedThing	host cell late endosome membrane	The lipid bilayer surrounding a host cell late endosome.	got7fsn_ti							jl	2009-10-15T03:00:39Z						cellular_component											owl:Class	
GO:1990320	biolink:NamedThing	collagen type XXI trimer	A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.	got7fsn_ti							bhm	2014-03-14T16:40:14Z						cellular_component											owl:Class	
GO:1990267	biolink:NamedThing	response to transition metal nanoparticle	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.	got7fsn_ti	response to colloidal metal|response to neutral metal atoms						sl	2014-01-10T17:16:41Z						biological_process											owl:Class	
GO:0004903	biolink:NamedThing	growth hormone receptor activity	Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0002131	biolink:NamedThing	wobble position cytosine ribose methylation	The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.	got7fsn_ti														biological_process											owl:Class	
GO:0002130	biolink:NamedThing	wobble position ribose methylation	The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position.	got7fsn_ti														biological_process											owl:Class	
GO:0098770	biolink:NamedThing	FBXO family protein binding	Binding to a member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.	got7fsn_ti														molecular_function											owl:Class	
GO:0022880	biolink:NamedThing	protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	N-acetylglucosamine PTS transporter activity													molecular_function											owl:Class	
GO:0015572	biolink:NamedThing	N-acetylglucosamine transmembrane transporter activity	Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.	got7fsn_ti	N-acetylchitosamine transmembrane transporter activity|N-Acetyl-D-glucosamine permease|D-GlcNAc transmembrane transporter activity|N-acetyl-D-glucosamine transmembrane transporter activity|N-acetylglucosamine permease activity										GO:0015580			molecular_function											owl:Class	
GO:0018141	biolink:NamedThing	peptide cross-linking via L-lysine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	got7fsn_ti												RESID:AA0245		biological_process											owl:Class	
GO:0140418	biolink:NamedThing	effector-mediated modulation of host process by symbiont	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	effector-dependent modulation of host process by symbiont|effector mediated modulation of host process by symbiont|effector triggered modulation of host process by symbiont	https://github.com/geneontology/go-ontology/issues/20971|https://github.com/geneontology/go-ontology/issues/18605					pg	2020-01-29T21:24:42Z						biological_process											owl:Class	
GO:0007294	biolink:NamedThing	germarium-derived oocyte fate determination	The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte cell fate determination|maintenance of oocyte identity										GO:0016350			biological_process											owl:Class	
GO:0030716	biolink:NamedThing	oocyte fate determination	The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	oocyte cell fate determination													biological_process											owl:Class	
GO:0051751	biolink:NamedThing	alpha-1,4-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.	got7fsn_ti														molecular_function											owl:Class	
GO:0042748	biolink:NamedThing	circadian sleep/wake cycle, non-REM sleep	All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.	got7fsn_ti														biological_process											owl:Class	
GO:0048283	biolink:NamedThing	indeterminate inflorescence morphogenesis	The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems.	got7fsn_ti														biological_process											owl:Class	
GO:0071374	biolink:NamedThing	cellular response to parathyroid hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.	got7fsn_ti							mah	2009-12-11T03:19:29Z						biological_process											owl:Class	
GO:0071107	biolink:NamedThing	response to parathyroid hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.	got7fsn_ti	response to parathyroid hormone stimulus						mah	2009-11-12T10:58:45Z						biological_process											owl:Class	
GO:0044238	biolink:NamedThing	primary metabolic process	The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.	got7fsn_ti	primary metabolism													biological_process											owl:Class	
GO:0003726	biolink:NamedThing	double-stranded RNA adenosine deaminase activity	Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.	got7fsn_ti	double-stranded RNA specific editase activity										GO:0003971	Reactome:R-HSA-77614|Reactome:R-HSA-77615		molecular_function											owl:Class	
GO:0004000	biolink:NamedThing	adenosine deaminase activity	Catalysis of the reaction: adenosine + H2O = inosine + NH3.	got7fsn_ti	adenosine aminohydrolase activity|adenosine deaminase reaction											Reactome:R-HSA-2161195|Reactome:R-HSA-2161187|Reactome:R-HSA-74241|RHEA:24408|MetaCyc:ADENODEAMIN-RXN|Reactome:R-HSA-5693346|EC:3.5.4.4		molecular_function											owl:Class	
GO:0042764	biolink:NamedThing	ascospore-type prospore	An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi.	got7fsn_ti														cellular_component											owl:Class	
GO:0042763	biolink:NamedThing	intracellular immature spore	A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants.	got7fsn_ti	forespore													cellular_component											owl:Class	
GO:0031670	biolink:NamedThing	cellular response to nutrient	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0007604	biolink:NamedThing	phototransduction, UV	The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.	got7fsn_ti	UV-sensitive opsin|phototransduction, ultraviolet radiation|phototransduction, UV light|phototransduction, UV radiation|phototransduction, ultraviolet light													biological_process											owl:Class	
GO:1901512	biolink:NamedThing	(-)-microperfuranone biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-microperfuranone.	got7fsn_ti	(-)-microperfuranone synthesis|(-)-microperfuranone biosynthesis|(-)-microperfuranone anabolism|(-)-microperfuranone formation						di	2012-10-18T06:54:18Z						biological_process											owl:Class	
GO:1901503	biolink:NamedThing	ether biosynthetic process	The chemical reactions and pathways resulting in the formation of ether.	got7fsn_ti	ether biosynthesis|ether formation|ether synthesis|ether anabolism						pr	2012-10-17T09:42:47Z						biological_process											owl:Class	
GO:0046217	biolink:NamedThing	indole phytoalexin metabolic process	The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response.	got7fsn_ti	indole phytoalexin metabolism													biological_process											owl:Class	
GO:0052314	biolink:NamedThing	phytoalexin metabolic process	The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.	got7fsn_ti	phytoalexin metabolism													biological_process											owl:Class	
GO:0097660	biolink:NamedThing	SCF-Cdc4 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.	got7fsn_ti							pr	2014-10-06T10:23:13Z						cellular_component											owl:Class	
GO:2000382	biolink:NamedThing	positive regulation of mesoderm development	Any process that activates or increases the frequency, rate or extent of mesoderm development.	got7fsn_ti							vk	2011-02-15T03:10:12Z						biological_process											owl:Class	
GO:2000380	biolink:NamedThing	regulation of mesoderm development	Any process that modulates the frequency, rate or extent of mesoderm development.	got7fsn_ti							vk	2011-02-15T03:09:46Z						biological_process											owl:Class	
GO:0085037	biolink:NamedThing	extrahaustorial membrane	The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane.	got7fsn_ti					See also: haustorium ; GO:0085035 and extrahaustorial matrix ; GO:0085036.		jl	2010-07-27T04:00:49Z						cellular_component											owl:Class	
GO:0071011	biolink:NamedThing	precatalytic spliceosome	A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.	got7fsn_ti	mammalian spliceosomal complex B|yeast spliceosomal complex A2-1|mammalian spliceosomal complex B1						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:2000946	biolink:NamedThing	negative regulation of amylopectin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process.	got7fsn_ti	negative regulation of Amylopectin catabolism						tt	2011-08-01T02:15:27Z						biological_process											owl:Class	
GO:2000882	biolink:NamedThing	negative regulation of starch catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process.	got7fsn_ti	negative regulation of starch degradation|negative regulation of starch catabolism|negative regulation of starch breakdown						bf	2011-07-27T03:23:46Z						biological_process											owl:Class	
GO:0022011	biolink:NamedThing	myelination in peripheral nervous system	The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.	got7fsn_ti	peripheral nervous system myelination													biological_process											owl:Class	
GO:0042552	biolink:NamedThing	myelination	The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.	got7fsn_ti	myelinogenesis											Wikipedia:Myelin		biological_process											owl:Class	
GO:0034899	biolink:NamedThing	trimethylamine monooxygenase activity	Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O.	got7fsn_ti												KEGG_REACTION:R05623|UM-BBD_reactionID:r1407|EC:1.14.13.148|RHEA:31979		molecular_function											owl:Class	
GO:0106211	biolink:NamedThing	inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity	Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate.	got7fsn_ti	5-PP-InsP4 activity|5-diphospho-myo-inositol 1,3,4,6-tetrakisphosphate diphosphatase activity|5-diphosphoinositol 1,3,4,6-tetrakisphosphate diphosphatase activity						hjd	2019-06-06T19:26:38Z				RHEA:59500		molecular_function											owl:Class	
GO:0052840	biolink:NamedThing	inositol diphosphate tetrakisphosphate diphosphatase activity	Catalysis of the reaction: inositol diphosphate tetrakisphosphate + H2O = inositol 1,3,4,5,6-pentakisphosphate + phosphate.	got7fsn_ti							ai	2011-11-29T04:14:22Z				MetaCyc:RXN-10963|EC:3.6.1.52|Reactome:R-HSA-1855166		molecular_function											owl:Class	
GO:0106314	biolink:NamedThing	nitrite reductase NADPH activity	Catalysis of the reaction: ammonium hydroxide + 3 NADP+ + H2O = nitrite + 3 NADPH + 3 H+.	got7fsn_ti							hjd	2020-09-23T14:28:27Z				RHEA:24632		molecular_function											owl:Class	
GO:0008942	biolink:NamedThing	nitrite reductase [NAD(P)H] activity	Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+.	got7fsn_ti	nitrite reductase [NAD(P)H2]|nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity|NAD(P)H2:nitrite oxidoreductase activity|NADPH-nitrite reductase activity|NAD(P)H:nitrite oxidoreductase activity|assimilatory nitrite reductase activity|ammonium-hydroxide:NAD(P)+ oxidoreductase activity|NADH-nitrite oxidoreductase activity				Note that this function was formerly EC:1.6.6.4.							MetaCyc:NITRITREDUCT-RXN|EC:1.7.1.4|KEGG_REACTION:R00789|KEGG_REACTION:R00787		molecular_function											owl:Class	
GO:0033373	biolink:NamedThing	maintenance of protease location in mast cell secretory granule	A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of protease localization in mast cell secretory granule|mast cell protease retention													biological_process											owl:Class	
GO:0033370	biolink:NamedThing	maintenance of protein location in mast cell secretory granule	A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.	got7fsn_ti	mast cell protein retention|maintenance of protein localization in mast cell secretory granule													biological_process											owl:Class	
GO:0052690	biolink:NamedThing	trichloro-p-hydroquinone reductive dehalogenase activity	Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl.	got7fsn_ti	trichlorohydroquinone reductive dehalogenase activity|pentaerythritol tetranitrate reductase activity|tetrachlorohydroquinone reductive dehalogenase activity|xenobiotic reductase activity											UM-BBD_reactionID:r0315|RHEA:56832		molecular_function											owl:Class	
GO:0002824	biolink:NamedThing	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.	got7fsn_ti														biological_process											owl:Class	
GO:0003221	biolink:NamedThing	right ventricular cardiac muscle tissue morphogenesis	The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.	got7fsn_ti	right ventricle myocardium morphogenesis						dph	2009-10-13T10:26:33Z						biological_process											owl:Class	
GO:0055010	biolink:NamedThing	ventricular cardiac muscle tissue morphogenesis	The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.	got7fsn_ti	cardiac ventricle muscle morphogenesis|ventricular heart muscle morphogenesis													biological_process											owl:Class	
GO:0102428	biolink:NamedThing	kaempferol-3-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose <=> kaempferol-3-gentiobioside + UDP.	got7fsn_ti												MetaCyc:RXN-13830		molecular_function											owl:Class	
GO:0003796	biolink:NamedThing	lysozyme activity	Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.	got7fsn_ti	N,O-diacetylmuramidase activity|peptidoglycan N-acetylmuramoylhydrolase activity|1,4-N-acetylmuramidase activity|L-7001|muramidase activity|mucopeptide N-acetylmuramoylhydrolase activity|PR1-lysozyme|globulin G|globulin G1|lysozyme g|mucopeptide glucohydrolase activity											MetaCyc:3.2.1.17-RXN|Reactome:R-HSA-8862320|EC:3.2.1.17		molecular_function											owl:Class	
GO:0018829	biolink:NamedThing	1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity	Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.	got7fsn_ti	DDD dehydrochlorinase activity											EC:4.5.1.-|UM-BBD_reactionID:r0513		molecular_function											owl:Class	
GO:0016848	biolink:NamedThing	carbon-halide lyase activity	Catalysis of the breakage of a bond between carbon and any halogen atom.	got7fsn_ti												EC:4.5.-.-		molecular_function											owl:Class	
GO:0010583	biolink:NamedThing	response to cyclopentenone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0060488	biolink:NamedThing	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.	got7fsn_ti	perpendicular dichotomous subdivision of terminal units involved in lung branching morphogenesis													biological_process											owl:Class	
GO:0007195	biolink:NamedThing	adenylate cyclase-inhibiting dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	got7fsn_ti	dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|dopamine receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by dopamine receptor signaling pathway													biological_process											owl:Class	
GO:0061299	biolink:NamedThing	retina vasculature morphogenesis in camera-type eye	The process in which the vasculature of the retina is generated and organized.	got7fsn_ti	retinal vasculature morphogenesis						dph	2010-09-06T03:28:25Z						biological_process											owl:Class	
GO:0031864	biolink:NamedThing	EP1 subtype prostaglandin E2 receptor binding	Binding to an EP1 subtype prostaglandin E2 receptor.	got7fsn_ti	prostanoid EP1 receptor binding|EP1 subtype prostaglandin E2 receptor ligand													molecular_function											owl:Class	
GO:0002093	biolink:NamedThing	auditory receptor cell morphogenesis	Any process that alters the size or shape of an auditory receptor cell.	got7fsn_ti	hair cell morphogenesis													biological_process											owl:Class	
GO:0102534	biolink:NamedThing	apigenin-7,4'-dimethyl ether 6-hydroxylase activity	Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ <=> ladanein + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-14751		molecular_function											owl:Class	
GO:0033713	biolink:NamedThing	choline:oxygen 1-oxidoreductase activity	Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide.	got7fsn_ti	choline oxidase activity											RHEA:13505|MetaCyc:CHOLINE-OXIDASE-RXN|EC:1.1.3.17		molecular_function											owl:Class	
GO:0000054	biolink:NamedThing	ribosomal subunit export from nucleus	The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.	got7fsn_ti	ribosomal subunit transport from nucleus to cytoplasm|ribosomal subunit-nucleus export|ribosome export from nucleus|ribosomal subunit export out of nucleus|ribosomal subunit export from cell nucleus													biological_process											owl:Class	
GO:0036260	biolink:NamedThing	RNA capping	The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts.	got7fsn_ti							bf	2012-06-15T02:10:23Z						biological_process											owl:Class	
GO:0004931	biolink:NamedThing	extracellularly ATP-gated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	got7fsn_ti	purinoceptor|purinoreceptor|P2X receptor				Note that this term refers to an activity and not a gene product. Consider also annotating to the molecular function term 'purinergic nucleotide receptor activity ; GO:0001614'.							Reactome:R-HSA-877187		molecular_function											owl:Class	
GO:0035381	biolink:NamedThing	ATP-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.	got7fsn_ti							bf	2010-03-18T01:21:45Z						molecular_function											owl:Class	
GO:0048373	biolink:NamedThing	lateral mesodermal cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	lateral plate mesodermal cell fate determination|lateral mesoderm cell fate determination|lateral plate mesoderm cell fate determination													biological_process											owl:Class	
GO:0031607	biolink:NamedThing	nuclear proteasome core complex, beta-subunit complex	The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0052096	biolink:NamedThing	formation of syncytium involving giant cell for nutrient acquisition	The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	formation by symbiont of syncytium involving giant cell for nutrient acquisition from host|formation by organism of syncytium involving giant cell for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305												biological_process											owl:Class	
GO:0052093	biolink:NamedThing	formation of specialized structure for nutrient acquisition	The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	formation by organism of specialized structure for nutrient acquisition from host|formation of specialized structure for nutrient acquisition from host|formation by symbiont of specialized structure for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305												biological_process											owl:Class	
GO:0018641	biolink:NamedThing	6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity	Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.	got7fsn_ti												UM-BBD_reactionID:r0048|EC:1.14.13.-		molecular_function											owl:Class	
GO:1902577	biolink:NamedThing	protein localization to medial cortical node	A process in which a protein is transported to, or maintained in, a location within a medial cortical node.	got7fsn_ti	protein localisation to medial cortical node|protein localisation in medial cortical node|protein localization in medial cortical node						mah	2013-12-17T14:09:28Z						biological_process											owl:Class	
GO:0052819	biolink:NamedThing	heteroglycan 2-alpha-mannosyltransferase activity	Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP.	got7fsn_ti	GDP mannose 2-alpha-mannosyltransferase activity|heteropolysaccharide 2-alpha-mannosyltransferase activity|GDP-mannose:heteroglycan 2-alpha-D-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan 2-alpha-mannosyltransferase activity						ai	2011-10-27T12:36:19Z				KEGG_REACTION:R03768|MetaCyc:2.4.1.48-RXN|EC:2.4.1.48		molecular_function											owl:Class	
GO:0047264	biolink:NamedThing	heteroglycan alpha-mannosyltransferase activity	Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP.	got7fsn_ti	GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase activity|heteropolysaccharide alpha-mannosyltransferase activity|GDP mannose alpha-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase activity											EC:2.4.1.48		molecular_function											owl:Class	
GO:0008388	biolink:NamedThing	testosterone 15-alpha-hydroxylase activity	Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O.	got7fsn_ti	cytochrome P450 CYP2A4													molecular_function											owl:Class	
GO:0032348	biolink:NamedThing	negative regulation of aldosterone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.	got7fsn_ti	inhibition of aldosterone biosynthetic process|down-regulation of aldosterone biosynthetic process|downregulation of aldosterone biosynthetic process|down regulation of aldosterone biosynthetic process													biological_process											owl:Class	
GO:0032345	biolink:NamedThing	negative regulation of aldosterone metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.	got7fsn_ti	down regulation of aldosterone metabolic process|inhibition of aldosterone metabolic process|downregulation of aldosterone metabolic process|down-regulation of aldosterone metabolic process|negative regulation of aldosterone metabolism													biological_process											owl:Class	
GO:0004409	biolink:NamedThing	homoaconitate hydratase activity	Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.	got7fsn_ti	homoaconitase activity|(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]|2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase activity|Lys4|LysF|cis-homoaconitase activity|HACN activity											KEGG_REACTION:R04371|MetaCyc:HOMOACONITATE-HYDRATASE-RXN|RHEA:15485|EC:4.2.1.36		molecular_function											owl:Class	
GO:0097505	biolink:NamedThing	Rad6-Rad18 complex	A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.	got7fsn_ti							pr	2013-09-26T13:42:58Z						cellular_component											owl:Class	
GO:0103096	biolink:NamedThing	CYP79F1 dihomomethionine monooxygenase activity	Catalysis of the reaction: dihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 5-methylthiopentanaldoxime + 3 H2O + carbon dioxide + 2 NADP.	got7fsn_ti												MetaCyc:RXNQT-4309|RHEA:32719		molecular_function											owl:Class	
GO:0004581	biolink:NamedThing	dolichyl-phosphate beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.	got7fsn_ti	polyprenyl phosphate:UDP-D-glucose glucosyltransferase activity|UDP-glucose:dolichyl phosphate glucosyltransferase activity|UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase activity|UDP-glucose:dolichyl monophosphate glucosyltransferase activity|UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase activity|uridine diphosphoglucose-dolichol glucosyltransferase activity|UDP-glucose dolichyl-phosphate glucosyltransferase activity|UDP-glucose:dolicholphosphoryl glucosyltransferase activity|UDP-glucose:dolichol phosphate glucosyltransferase activity											MetaCyc:2.4.1.117-RXN|RHEA:15401|Reactome:R-HSA-446214|EC:2.4.1.117		molecular_function											owl:Class	
GO:0035815	biolink:NamedThing	positive regulation of renal sodium excretion	Any process that increases the amount of sodium excreted in urine over a unit of time.	got7fsn_ti	natriuresis				The amount of sodium excreted in urine over a unit of time can be increased by increasing the volume of urine produced (diuresis) and/or by increasing the concentration of sodium in the urine.		bf	2011-04-20T01:29:26Z						biological_process											owl:Class	
GO:0047966	biolink:NamedThing	glycosulfatase activity	Catalysis of the reaction: D-glucose 6-sulfate + H(2)O = D-glucose + H(+) + sulfate.	got7fsn_ti	glucosulfatase activity|sugar-sulfate sulfohydrolase activity|glycosulphatase activity											KEGG_REACTION:R00534|EC:3.1.6.3|MetaCyc:GLYCOSULFATASE-RXN|RHEA:19145		molecular_function											owl:Class	
GO:0038153	biolink:NamedThing	CCL2-activated CCR4 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CCL2/CCR4 signaling pathway						bf	2012-05-11T11:44:48Z						biological_process											owl:Class	
GO:0038148	biolink:NamedThing	chemokine (C-C motif) ligand 2 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CCL2 signaling pathway						bf	2012-05-11T11:36:08Z						biological_process											owl:Class	
GO:0030330	biolink:NamedThing	DNA damage response, signal transduction by p53 class mediator	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.	got7fsn_ti	p53 signaling pathway|TP53 signaling pathway|p53-mediated DNA damage response|DNA damage response, activation of p53										GO:0006976			biological_process											owl:Class	
GO:0097708	biolink:NamedThing	intracellular vesicle	Any vesicle that is part of the intracellular region.	got7fsn_ti							pr	2016-03-29T17:39:45Z						cellular_component											owl:Class	
GO:0002475	biolink:NamedThing	antigen processing and presentation via MHC class Ib	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.	got7fsn_ti														biological_process											owl:Class	
GO:0018084	biolink:NamedThing	peptidyl-lactic acid biosynthetic process from peptidyl-serine	The modification of N-terminal peptidyl-serine to lactic acid.	got7fsn_ti	peptidyl-lactic acid formation from peptidyl-serine|peptidyl-lactic acid anabolism from peptidyl-serine|peptidyl-lactic acid synthesis from peptidyl-serine											RESID:AA0186		biological_process											owl:Class	
GO:0102544	biolink:NamedThing	ornaline synthase activity	Catalysis of the reaction: L-ornithinium(1+) + 2-oxoglutarate + NADPH + H+ <=> ornaline + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-14880		molecular_function											owl:Class	
GO:0032455	biolink:NamedThing	nerve growth factor processing	The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.	got7fsn_ti	NGF processing|beta-nerve growth factor processing													biological_process											owl:Class	
GO:0039613	biolink:NamedThing	suppression by virus of host protein phosphorylation	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of phosphorylation of viral or host proteins in a host.	got7fsn_ti	viral inhibition of host protein phosphorylation						bf	2012-07-06T11:15:56Z						biological_process											owl:Class	
GO:0033194	biolink:NamedThing	response to hydroperoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.	got7fsn_ti														biological_process											owl:Class	
GO:0031099	biolink:NamedThing	regeneration	The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).	got7fsn_ti												Wikipedia:Regeneration_(biology)		biological_process											owl:Class	
GO:0045301	biolink:NamedThing	tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity	Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin.	got7fsn_ti	tRNA-(ms2io6A)-hydroxylase activity|tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity|2-methylthio-cis-ribozeatin hydroxylase activity													molecular_function											owl:Class	
GO:0047288	biolink:NamedThing	monosialoganglioside sialyltransferase activity	Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP.	got7fsn_ti	CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase activity											RHEA:18021|EC:2.4.99.2|MetaCyc:2.4.99.2-RXN		molecular_function											owl:Class	
GO:0050599	biolink:NamedThing	deacetoxycephalosporin-C synthase activity	Catalysis of the reaction: 2-oxoglutarate + O(2) + penicillin N = CO(2) + deacetoxycephalosporin C + H(2)O + succinate.	got7fsn_ti	deacetoxycephalosporin C synthetase activity|DAOC synthase activity|penicillin N expandase activity|penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)|DAOCS activity|expandase activity										GO:0045441	EC:1.14.20.1|MetaCyc:1.14.20.1-RXN|KEGG_REACTION:R05301|RHEA:20748		molecular_function											owl:Class	
GO:0004578	biolink:NamedThing	chitobiosyldiphosphodolichol beta-mannosyltransferase activity	Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol.	got7fsn_ti	GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase activity|guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase activity|GDP-mannose-dolichol diphosphochitobiose mannosyltransferase activity											Reactome:R-HSA-446218|RHEA:13865|EC:2.4.1.142|MetaCyc:2.4.1.142-RXN|Reactome:R-HSA-4549382		molecular_function											owl:Class	
GO:0019187	biolink:NamedThing	beta-1,4-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.	got7fsn_ti														molecular_function											owl:Class	
GO:0018491	biolink:NamedThing	2-oxobutyrate synthase activity	Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin.	got7fsn_ti	2-ketobutyrate synthase activity|alpha-ketobutyrate-ferredoxin oxidoreductase activity|2-oxobutyrate-ferredoxin oxidoreductase activity|2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating)|alpha-ketobutyrate synthase activity											MetaCyc:2-OXOBUTYRATE-SYNTHASE-RXN|UM-BBD_reactionID:r0358|RHEA:32135		molecular_function											owl:Class	
GO:0007091	biolink:NamedThing	metaphase/anaphase transition of mitotic cell cycle	The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.	got7fsn_ti	mitotic metaphase/anaphase transition|metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process													biological_process											owl:Class	
GO:0010965	biolink:NamedThing	regulation of mitotic sister chromatid separation	Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.	got7fsn_ti							tb	2009-05-20T11:39:07Z						biological_process											owl:Class	
GO:0031989	biolink:NamedThing	bombesin receptor signaling pathway	The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands.	got7fsn_ti	bombesin receptor signalling pathway													biological_process											owl:Class	
GO:0030032	biolink:NamedThing	lamellipodium assembly	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.	got7fsn_ti	lamellipodium formation|lamellipodium biogenesis|lamellipodium biosynthesis													biological_process											owl:Class	
GO:0046797	biolink:NamedThing	viral procapsid maturation	The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure.	got7fsn_ti	capsid maturation|virion maturation|viral capsid maturation											UniProtKB-KW:KW-1273		biological_process											owl:Class	
GO:0009028	biolink:NamedThing	tartronate-semialdehyde synthase activity	Catalysis of the reaction: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2).	got7fsn_ti	hydroxymalonic semialdehyde carboxylase activity|glyoxylate carboligase activity|glyoxylate carbo-ligase activity|glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)|tartronic semialdehyde carboxylase activity|tartronate semialdehyde carboxylase activity|glyoxylic carbo-ligase activity|glyoxylate carboxy-lyase (dimerizing)|glyoxalate carboligase activity											EC:4.1.1.47|KEGG_REACTION:R00013|RHEA:10136|MetaCyc:GLYOCARBOLIG-RXN		molecular_function											owl:Class	
GO:0072257	biolink:NamedThing	metanephric nephron tubule epithelial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-03-19T04:11:02Z						biological_process											owl:Class	
GO:0072160	biolink:NamedThing	nephron tubule epithelial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-02-24T02:40:11Z						biological_process											owl:Class	
GO:0070447	biolink:NamedThing	positive regulation of oligodendrocyte progenitor proliferation	Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.	got7fsn_ti	positive regulation of oligodendrocyte precursor proliferation													biological_process											owl:Class	
GO:0014015	biolink:NamedThing	positive regulation of gliogenesis	Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.	got7fsn_ti	activation of gliogenesis|up-regulation of gliogenesis|up regulation of gliogenesis|upregulation of gliogenesis|stimulation of gliogenesis													biological_process											owl:Class	
GO:0047302	biolink:NamedThing	UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity	Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose.	got7fsn_ti	UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity|uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity|UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose transaminase activity|UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase activity											MetaCyc:2.6.1.34-RXN|EC:2.6.1.34|KEGG_REACTION:R04529|RHEA:31663		molecular_function											owl:Class	
GO:0039647	biolink:NamedThing	suppression by virus of host poly(A)-binding protein activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host poly(A)-binding protein (PABP) activity. PABP binds to the poly(A) tail of mRNA to facilitate translation.	got7fsn_ti	inhibition of host poly(A)-binding protein by virus|suppression by virus of host PABP activity						bf	2012-10-09T15:14:07Z						biological_process											owl:Class	
GO:0106371	biolink:NamedThing	fluorescent chlorophyll catabolite monooxygenase (deformylase) activity	Catalysis of the reaction: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H+ + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite.	got7fsn_ti							hjd	2021-04-01T16:32:56Z						molecular_function											owl:Class	
GO:0032346	biolink:NamedThing	positive regulation of aldosterone metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.	got7fsn_ti	stimulation of aldosterone metabolic process|positive regulation of aldosterone metabolism|up-regulation of aldosterone metabolic process|upregulation of aldosterone metabolic process|up regulation of aldosterone metabolic process|activation of aldosterone metabolic process													biological_process											owl:Class	
GO:0016740	biolink:NamedThing	transferase activity	Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.	got7fsn_ti												Reactome:R-HSA-8868783|Reactome:R-HSA-1483089|Reactome:R-HSA-5668414|Reactome:R-HSA-1483186|EC:2.-.-.-		molecular_function											owl:Class	
GO:0006776	biolink:NamedThing	vitamin A metabolic process	The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.	got7fsn_ti	vitamin A metabolism													biological_process											owl:Class	
GO:0006775	biolink:NamedThing	fat-soluble vitamin metabolic process	The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.	got7fsn_ti	fat-soluble vitamin metabolism													biological_process											owl:Class	
GO:0051878	biolink:NamedThing	lateral element assembly	The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements.	got7fsn_ti														biological_process											owl:Class	
GO:0102771	biolink:NamedThing	sphingolipid very long chain fatty acid alpha-hydroxylase activity	Catalysis of the reaction: O2 + NADPH + H+ + a dihydroceramide = NADP + H2O + an alpha hydroxydihydroceramide.	got7fsn_ti												MetaCyc:RXN-7796|RHEA:46512		molecular_function											owl:Class	
GO:0035174	biolink:NamedThing	histone serine kinase activity	Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic  chromosomes.	got7fsn_ti	histone-serine kinase activity													molecular_function											owl:Class	
GO:0003973	biolink:NamedThing	(S)-2-hydroxy-acid oxidase activity	Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.	got7fsn_ti	hydroxyacid oxidase A|very-long-chain-(S)-2-hydroxy-acid oxidase activity|medium-chain-(S)-2-hydroxy-acid oxidase activity|hydroxy-acid oxidase A activity|long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity|L-alpha-hydroxy acid oxidase|glycolate oxidase activity|L-2-hydroxy acid oxidase|hydroxy-acid oxidase B activity	https://github.com/geneontology/go-ontology/issues/21795									GO:0052852|GO:0052853|GO:0008891|GO:0052854	MetaCyc:S-2-HYDROXY-ACID-OXIDASE-RXN|EC:1.1.3.15|Reactome:R-HSA-6787811|Reactome:R-HSA-389842|RHEA:16789|MetaCyc:RXN-969		molecular_function											owl:Class	
GO:1990726	biolink:NamedThing	Lsm1-7-Pat1 complex	A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway.	got7fsn_ti							pr	2015-04-08T09:22:36Z						cellular_component											owl:Class	
GO:0001840	biolink:NamedThing	neural plate development	The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:1903039	biolink:NamedThing	positive regulation of leukocyte cell-cell adhesion	Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.	got7fsn_ti	up regulation of leukocyte adhesion|activation of leukocyte adhesion|up-regulation of leukocyte adhesion|activation of leukocyte cell adhesion|up regulation of leukocyte cell adhesion|up-regulation of leukocyte cell-cell adhesion|upregulation of leukocyte adhesion|up regulation of leukocyte cell-cell adhesion|activation of leukocyte cell-cell adhesion|upregulation of leukocyte cell-cell adhesion|positive regulation of leukocyte adhesion|up-regulation of leukocyte cell adhesion|upregulation of leukocyte cell adhesion|positive regulation of leukocyte cell adhesion				Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion		rl	2014-05-19T15:30:15Z						biological_process											owl:Class	
GO:0022409	biolink:NamedThing	positive regulation of cell-cell adhesion	Any process that activates or increases the rate or extent of cell adhesion to another cell.	got7fsn_ti	stimulation of cell-cell adhesion|up regulation of cell-cell adhesion|upregulation of cell-cell adhesion|activation of cell-cell adhesion|up-regulation of cell-cell adhesion													biological_process											owl:Class	
GO:0098823	biolink:NamedThing	peptidyl-cysteine modification to S-amindino-L-cysteine	The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.	got7fsn_ti												RESID:AA0335		biological_process											owl:Class	
GO:0072596	biolink:NamedThing	establishment of protein localization to chloroplast	The directed movement of a protein to a specific location in a chloroplast.	got7fsn_ti	establishment of protein localisation to chloroplast						mah	2011-02-14T02:16:13Z						biological_process											owl:Class	
GO:0046544	biolink:NamedThing	development of secondary male sexual characteristics	The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0045136	biolink:NamedThing	development of secondary sexual characteristics	The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0018255	biolink:NamedThing	peptide cross-linking via S-glycyl-L-cysteine	The formation of S-(peptidyl-glycyl)-peptidyl-cysteine cross-links by the formation of a thiolester between cysteine and the carboxy-terminal glycine of ubiquitin and other proteins.	got7fsn_ti												RESID:AA0206		biological_process											owl:Class	
GO:0051450	biolink:NamedThing	myoblast proliferation	The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0098771	biolink:NamedThing	inorganic ion homeostasis	Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0009627	biolink:NamedThing	systemic acquired resistance	The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.	got7fsn_ti	salicylic acid-dependent systemic resistance											Wikipedia:Systemic_acquired_resistance		biological_process											owl:Class	
GO:0097275	biolink:NamedThing	cellular ammonium homeostasis	Any biological process involved in the maintenance of an internal steady state of ammonium at the level of the cell.	got7fsn_ti	cellular ammonia homeostasis						pr	2012-03-22T02:54:38Z						biological_process											owl:Class	
GO:0097272	biolink:NamedThing	ammonium homeostasis	Any biological process involved in the maintenance of an internal steady state of ammonium.	got7fsn_ti	ammonia homeostasis						pr	2012-03-22T02:51:22Z						biological_process											owl:Class	
GO:0003182	biolink:NamedThing	coronary sinus valve morphogenesis	The process in which the structure of the coronary sinus valve is generated and organized.	got7fsn_ti							dph	2009-10-08T11:33:31Z						biological_process											owl:Class	
GO:0048613	biolink:NamedThing	embryonic ectodermal digestive tract morphogenesis	The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.	got7fsn_ti	embryonic ectodermal gut morphogenesis													biological_process											owl:Class	
GO:0061983	biolink:NamedThing	meiosis II cell cycle process	A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.	got7fsn_ti	second meiotic division						dph	2018-02-14T22:37:44Z						biological_process											owl:Class	
GO:1903046	biolink:NamedThing	meiotic cell cycle process	A process that is part of the meiotic cell cycle.	got7fsn_ti							jl	2014-05-22T14:22:28Z						biological_process											owl:Class	
GO:0018052	biolink:NamedThing	C-terminal peptidyl-tyrosine amidation	The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0099		biological_process											owl:Class	
GO:0003755	biolink:NamedThing	peptidyl-prolyl cis-trans isomerase activity	Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).	got7fsn_ti	peptidyl-prolyl isomerase B reaction|FK506-sensitive peptidyl-prolyl cis-trans isomerase|peptidylprolyl cis-trans isomerase activity|parvulin|peptide bond isomerase activity|peptidylproline cis-trans-isomerase activity|cis-trans proline isomerase activity|peptidylprolyl isomerase activity|juglone-sensitive peptidyl-prolyl cis-trans isomerase activity|immunophilin|PPIase activity|rotamase activity|cyclophilin activity|cyclophilin-type peptidyl-prolyl cis-trans isomerase activity|juglone-sensitive cis-trans proline isomerase activity										GO:0042028|GO:0004752	Reactome:R-HSA-2022073|EC:5.2.1.8|Reactome:R-HSA-9626816|MetaCyc:PEPTIDYLPROLYL-ISOMERASE-RXN|RHEA:16237		molecular_function											owl:Class	
GO:0045052	biolink:NamedThing	protein insertion into ER membrane by GPI attachment sequence	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which proteins become anchored to the phospholipid bilayer by a covalently attached glycosylphosphatidylinositol (GPI) molecule.	got7fsn_ti	protein-ER insertion by GPI attachment sequence|GPI attachment sequence mediated protein insertion into ER membrane|protein insertion into ER membrane, GPI attachment sequence mediated|protein-endoplasmic reticulum insertion by GPI attachment sequence|protein insertion into endoplasmic reticulum membrane by GPI attachment sequence													biological_process											owl:Class	
GO:0090094	biolink:NamedThing	metanephric cap mesenchymal cell proliferation involved in metanephros development	The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.	got7fsn_ti							tb	2009-11-13T10:34:10Z						biological_process											owl:Class	
GO:0010447	biolink:NamedThing	response to acidic pH	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti	response to acidity				This term should be used to annotate instances where a cell or organism is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0001101 'response to acid chemical'.									biological_process											owl:Class	
GO:0034189	biolink:NamedThing	very-low-density lipoprotein particle binding	Binding to a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm.	got7fsn_ti	very-low-density lipoprotein binding|VLDL binding													molecular_function											owl:Class	
GO:0014062	biolink:NamedThing	regulation of serotonin secretion	Any process that modulates the frequency, rate or extent of the regulated release of serotonin.	got7fsn_ti	regulation of serotonin release													biological_process											owl:Class	
GO:0048669	biolink:NamedThing	collateral sprouting in absence of injury	The process in which outgrowths develop from the axons of intact undamaged neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0070330	biolink:NamedThing	aromatase activity	Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.	got7fsn_ti	estrogen synthetase activity											RHEA:17149|EC:1.14.14.1|UM-BBD_enzymeID:e0551|MetaCyc:UNSPECIFIC-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0102475	biolink:NamedThing	2-hydroxyeriodictyol 6C-glucoside dehydratase activity	Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol <=> isoorientin + H2O.	got7fsn_ti												MetaCyc:RXN-14081		molecular_function											owl:Class	
GO:0004119	biolink:NamedThing	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.	got7fsn_ti														molecular_function											owl:Class	
GO:1990398	biolink:NamedThing	Cus cation efflux complex	Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic growth.	got7fsn_ti	copper efflux complex|copper efflux system|silver efflux system|Cus cation efflux system|silver efflux complex				An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:23122209.		bhm	2014-06-11T08:51:48Z						cellular_component											owl:Class	
GO:1903113	biolink:NamedThing	copper ion transmembrane transporter complex	A protein complex which is capable of copper ion transmembrane transporter activity.	got7fsn_ti					An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:23122209 (inferred from direct assay).		bhm	2014-06-10T09:54:48Z						cellular_component											owl:Class	
GO:0047023	biolink:NamedThing	androsterone dehydrogenase activity	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.	got7fsn_ti	3(or 17)alpha-hydroxysteroid dehydrogenase activity|3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity|3(17)alpha-hydroxysteroid dehydrogenase activity|3(or 17)-alpha-hydroxysteroid dehydrogenase activity											EC:1.1.1.209|MetaCyc:1.1.1.209-RXN		molecular_function											owl:Class	
GO:0003249	biolink:NamedThing	cell proliferation involved in heart valve morphogenesis	The multiplication or reproduction of cells that contributes to the shaping of a heart valve.	got7fsn_ti							dph	2009-10-13T01:59:19Z						biological_process											owl:Class	
GO:0061323	biolink:NamedThing	cell proliferation involved in heart morphogenesis	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.	got7fsn_ti							dph	2010-09-28T09:05:26Z						biological_process											owl:Class	
GO:0006553	biolink:NamedThing	lysine metabolic process	The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid.	got7fsn_ti	lysine metabolism											Wikipedia:Lysine		biological_process											owl:Class	
GO:0009066	biolink:NamedThing	aspartate family amino acid metabolic process	The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.	got7fsn_ti	aspartate family amino acid metabolism													biological_process											owl:Class	
GO:0047458	biolink:NamedThing	beta-pyrazolylalanine synthase activity	Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+).	got7fsn_ti	BPA-synthase activity|O3-acetyl-L-serine acetate-lyase (adding pyrazole)|O(3)-acetyl-L-serine acetate-lyase (adding pyrazole) activity|O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity|beta-(1-pyrazolyl)alanine synthase activity|beta-pyrazolylalanine synthase (acetylserine) activity|beta-pyrazolealanine synthase activity|3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity|pyrazolealanine synthase activity|pyrazolylalaninase activity											MetaCyc:2.5.1.51-RXN|EC:2.5.1.51|KEGG_REACTION:R03134|RHEA:13117		molecular_function											owl:Class	
GO:0097161	biolink:NamedThing	DH domain binding	Binding to a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket.	got7fsn_ti							pr	2011-09-27T10:06:09Z						molecular_function											owl:Class	
GO:0035123	biolink:NamedThing	embryonic dorsal fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.	got7fsn_ti														biological_process											owl:Class	
GO:0102235	biolink:NamedThing	1-penten-3-one reductase activity	Catalysis of the reaction: 1-penten-3-one + NADPH + H+ <=> 1-pentan-3-one + NADP.	got7fsn_ti												MetaCyc:RXN-12295		molecular_function											owl:Class	
GO:0042054	biolink:NamedThing	histone methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.	got7fsn_ti	histone methylase activity											EC:2.1.1.354		molecular_function											owl:Class	
GO:0006279	biolink:NamedThing	premeiotic DNA replication	The replication of DNA that precedes meiotic cell division.	got7fsn_ti	nuclear cell cycle DNA replication involved in meiotic cell cycle|meiotic cell cycle DNA replication|DNA replication during S phase involved in meiotic cell cycle|meiotic DNA replication|premeiotic DNA synthesis|meiotic nuclear cell cycle DNA replication|DNA replication involved in S-phase involved in meiotic cell cycle|meiotic DNA synthesis|DNA replication involved in S phase involved in meiotic cell cycle										GO:1902968			biological_process											owl:Class	
GO:0033260	biolink:NamedThing	nuclear DNA replication	The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.	got7fsn_ti	DNA replication involved in S-phase|DNA replication during S phase|nuclear cell cycle DNA replication|DNA replication involved in S phase													biological_process											owl:Class	
GO:0048500	biolink:NamedThing	signal recognition particle	A complex of protein and RNA which facilitates translocation of proteins across membranes.	got7fsn_ti												Wikipedia:Signal_recognition_particle		cellular_component											owl:Class	
GO:0071125	biolink:NamedThing	alphaV-beta3 integrin-EGFR complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.	got7fsn_ti	ITGAV-ITGB3-EGFR complex						mah	2009-11-13T02:23:18Z						cellular_component											owl:Class	
GO:0060665	biolink:NamedThing	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.	got7fsn_ti	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalling						dph	2009-06-01T08:42:36Z						biological_process											owl:Class	
GO:0071626	biolink:NamedThing	mastication	The process of biting and mashing food with the teeth prior to swallowing.	got7fsn_ti	chewing						mah	2010-02-10T11:19:48Z						biological_process											owl:Class	
GO:0044821	biolink:NamedThing	meiotic telomere tethering at nuclear periphery	The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle.	got7fsn_ti							jl	2013-11-19T16:18:09Z						biological_process											owl:Class	
GO:0034398	biolink:NamedThing	telomere tethering at nuclear periphery	The process in which a telomere is maintained in a specific location at the nuclear periphery.	got7fsn_ti														biological_process											owl:Class	
GO:2000846	biolink:NamedThing	regulation of corticosteroid hormone secretion	Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion.	got7fsn_ti	regulation of corticosteroid secretion						bf	2011-07-26T08:43:38Z						biological_process											owl:Class	
GO:0008962	biolink:NamedThing	phosphatidylglycerophosphatase activity	Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.	got7fsn_ti	PGP phosphatase activity|phosphatidylglycerol phosphate phosphatase activity|phosphatidylglycerol phosphatase activity|phosphatidylglycerophosphate phosphohydrolase activity											EC:3.1.3.27|MetaCyc:PGPPHOSPHA-RXN|RHEA:16725|Reactome:R-HSA-1483197		molecular_function											owl:Class	
GO:0021736	biolink:NamedThing	globose nucleus development	The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0036411	biolink:NamedThing	H-NS-Cnu complex	A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes.	got7fsn_ti							bf	2013-08-22T10:19:24Z						cellular_component											owl:Class	
GO:0017053	biolink:NamedThing	transcription repressor complex	A protein complex that possesses activity that prevents or downregulates transcription.	got7fsn_ti	nuclear transcriptional repressor complex|transcriptional repressor complex|cytoplasmic transcriptional repressor complex|transcription factor inhibitor complex						tb	2014-05-09T13:23:51Z			GO:0090568|GO:0090569			cellular_component											owl:Class	
GO:0106334	biolink:NamedThing	3'-deoxyribose phosphate lyase activity	Catalysis of the conversion of a 3'-deoxyribose phosphate in DNA to a 3'-phosphate.	got7fsn_ti	3'-dRP lyase activity|3'-dRP lyase						hjd	2020-10-20T19:04:24Z						molecular_function											owl:Class	
GO:0097301	biolink:NamedThing	regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter	Any process that regulates the internal concentration of potassium ions at the level of a cell by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter|cellular potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter						pr	2012-05-09T09:03:02Z						biological_process											owl:Class	
GO:0004097	biolink:NamedThing	catechol oxidase activity	Catalysis of the reaction: 2 L-dopa + O2 = 2 H2O + 2 L-dopaquinone. This reaction catalyzes exclusively the oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones.	got7fsn_ti	polyphenol oxidase activity|tyrosinase activity|diphenol oxidase activity|pyrocatechol oxidase|L-DOPA monooxygenase activity|L-dopa oxidase activity|phenolase activity|catecholase|dopamine monooxygenase activity|o-diphenol oxidoreductase|o-diphenolase activity	https://github.com/geneontology/go-ontology/issues/21024			GO:0004097 describes oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones. For monooxygenation of monophenols, consider instead the term 'monophenol monooxygenase activity ; GO:0004503'.						GO:0102316|GO:0036264|GO:0036263	MetaCyc:CATECHOL-OXIDASE-RXN|MetaCyc:RXN-13061|EC:1.10.3.1|RHEA:21632		molecular_function											owl:Class	
GO:0045046	biolink:NamedThing	protein import into peroxisome membrane	The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.	got7fsn_ti	peroxisome membrane protein import|protein transport into peroxisome membrane													biological_process											owl:Class	
GO:0048526	biolink:NamedThing	imaginal disc-derived wing expansion	The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.	got7fsn_ti	wing expansion|wing inflation													biological_process											owl:Class	
GO:0007062	biolink:NamedThing	sister chromatid cohesion	The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.	got7fsn_ti	sister chromatid alignment|coheson-mediated DNA tethering													biological_process											owl:Class	
GO:0004818	biolink:NamedThing	glutamate-tRNA ligase activity	Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).	got7fsn_ti	L-glutamate:tRNAGlu ligase (AMP-forming) activity|glutamyl-transfer ribonucleic acid synthetase activity|glutamyl-tRNA synthetase activity|glutamic acid translase activity|glutamyl-transfer RNA synthetase activity|glutamyl-transfer ribonucleate synthetase activity|glutamate-tRNA synthetase activity											MetaCyc:GLURS-RXN|RHEA:23540|Reactome:R-HSA-380216|EC:6.1.1.17|Reactome:R-HSA-379861		molecular_function											owl:Class	
GO:0004764	biolink:NamedThing	shikimate 3-dehydrogenase (NADP+) activity	Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.	got7fsn_ti	5-dehydroshikimic reductase activity|shikimate:NADP(+) oxidoreductase activity|shikimate oxidoreductase activity|5-dehydroshikimate reductase activity|shikimate:NADP(+) 5-oxidoreductase activity|DHS reductase activity|dehydroshikimic reductase activity											EC:1.1.1.282|RHEA:17737|MetaCyc:SHIKIMATE-5-DEHYDROGENASE-RXN|EC:1.1.1.25|KEGG_REACTION:R06847		molecular_function											owl:Class	
GO:0019729	biolink:NamedThing	peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine	The formation of the fluorescent protein FP583 chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	got7fsn_ti	biosynthesis of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine				See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.							RESID:AA0189		biological_process											owl:Class	
GO:0035789	biolink:NamedThing	metanephric mesenchymal cell migration	The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.	got7fsn_ti	metanephric mesenchyme chemotaxis						bf	2011-04-06T10:45:15Z						biological_process											owl:Class	
GO:0035788	biolink:NamedThing	cell migration involved in metanephros development	The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.	got7fsn_ti	cell migration involved in metanephric kidney development						bf	2011-04-06T10:42:21Z						biological_process											owl:Class	
GO:0003208	biolink:NamedThing	cardiac ventricle morphogenesis	The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.	got7fsn_ti							dph	2009-10-13T09:38:44Z						biological_process											owl:Class	
GO:0033117	biolink:NamedThing	esterosome	A vesicle filled with crystalline protein that shows sequence similarities with various esterases.	got7fsn_ti														cellular_component											owl:Class	
GO:0047038	biolink:NamedThing	D-arabinitol 2-dehydrogenase activity	Catalysis of the reaction: D-arabinitol + NAD(+) = D-ribulose + H(+) + NADH.	got7fsn_ti	D-arabinitol 2-dehydrogenase (ribulose-forming) activity|D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming)											RHEA:17389|MetaCyc:1.1.1.250-RXN|EC:1.1.1.250|KEGG_REACTION:R07134		molecular_function											owl:Class	
GO:0019976	biolink:NamedThing	interleukin-2 binding	Binding to interleukin-2.	got7fsn_ti	IL-2 binding													molecular_function											owl:Class	
GO:0050565	biolink:NamedThing	aerobactin synthase activity	Catalysis of the reaction: 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 4 ATP + citrate + 2 H(2)O = 4 ADP + aerobactin + 8 H(+) + 4 phosphate.	got7fsn_ti	citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase (ADP-forming)|citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (ADP-forming)											KEGG_REACTION:R04357|RHEA:11760|MetaCyc:6.3.2.27-RXN		molecular_function											owl:Class	
GO:0047573	biolink:NamedThing	4-acetamidobutyrate deacetylase activity	Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.	got7fsn_ti	4-acetamidobutanoate amidohydrolase activity											RHEA:15897|EC:3.5.1.63|MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN		molecular_function											owl:Class	
GO:0008914	biolink:NamedThing	leucyltransferase activity	Catalysis of the reaction: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein.	got7fsn_ti	leucyl-tRNA--protein transferase activity|leucyl/phenylalanyl-tRNA--protein transferase activity|leucyl, phenylalanine-tRNA-protein transferase activity|leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase activity|L-leucyl-tRNA:protein leucyltransferase activity|leucyl-phenylalanine-transfer ribonucleate-protein transferase activity|L/F transferase activity											EC:2.3.2.6|MetaCyc:LEUCYLTRANSFERASE-RXN|RHEA:12340		molecular_function											owl:Class	
GO:0102420	biolink:NamedThing	sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate.	got7fsn_ti												MetaCyc:RXN-13805|EC:2.3.1.15		molecular_function											owl:Class	
GO:0070616	biolink:NamedThing	regulation of thiamine diphosphate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.	got7fsn_ti	regulation of thiamine diphosphate biosynthesis|regulation of thiamine diphosphate anabolism|regulation of thiamin diphosphate biosynthetic process|regulation of thiamine diphosphate formation|regulation of thiamine diphosphate synthesis						mah	2009-04-29T03:37:35Z						biological_process											owl:Class	
GO:0030656	biolink:NamedThing	regulation of vitamin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	got7fsn_ti	regulation of vitamin metabolism													biological_process											owl:Class	
GO:0008782	biolink:NamedThing	adenosylhomocysteine nucleosidase activity	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine.	got7fsn_ti	S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase activity|S-adenosylhomocysteine hydrolase activity|S-adenosyl-L-homocysteine homocysteinylribohydrolase activity|S-adenosylhomocysteine nucleosidase activity|5'-methyladenosine nucleosidase activity|AdoHcy/MTA nucleosidase activity											RHEA:17805|EC:3.2.2.9|MetaCyc:ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN		molecular_function											owl:Class	
GO:0021885	biolink:NamedThing	forebrain cell migration	The orderly movement of a cell from one site to another at least one of which is located in the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0097002	biolink:NamedThing	mitochondrial inner boundary membrane	The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane.	got7fsn_ti	inner bounding mitochondrial membrane						pr	2011-03-10T04:11:50Z				NIF_Subcellular:sao18461326		cellular_component											owl:Class	
GO:1990305	biolink:NamedThing	RAD6-UBR2 ubiquitin ligase complex	A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation.	got7fsn_ti	RAD6-UBR2 complex				This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:15504724		bhm	2014-03-03T22:14:32Z						cellular_component											owl:Class	
GO:0052546	biolink:NamedThing	cell wall pectin metabolic process	The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.	got7fsn_ti	cell wall pectin metabolism|plant-type cell wall pectin metabolic process|pectin metabolism during cell wall biogenesis|cellulose and pectin-containing cell wall pectin metabolic process													biological_process											owl:Class	
GO:1902694	biolink:NamedThing	superoxide dismutase copper chaperone complex	A protein complex which is capable of superoxide dismutase copper chaperone activity.	got7fsn_ti					An example of this is CCS1 in Saccharomyces cerevisiae S288c (UniProt symbol P40202) in PMID:10426947.		bhm	2014-02-18T11:13:45Z						cellular_component											owl:Class	
GO:1902695	biolink:NamedThing	metallochaperone complex	A protein complex which is capable of metallochaperone activity.	got7fsn_ti							bhm	2014-02-18T11:34:40Z						cellular_component											owl:Class	
GO:0097273	biolink:NamedThing	creatinine homeostasis	Any biological process involved in the maintenance of an internal steady state of creatinine.	got7fsn_ti							pr	2012-03-22T02:52:50Z						biological_process											owl:Class	
GO:1990615	biolink:NamedThing	Kelch-containing formin regulatory complex	A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p.	got7fsn_ti	Bud14-Kel1-Kel2 complex|KFRC complex						mcc	2015-01-21T18:48:51Z						cellular_component											owl:Class	
GO:0043843	biolink:NamedThing	ADP-specific glucokinase activity	Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.	got7fsn_ti	ADP:D-glucose 6-phosphotransferase activity|ADP-dependent glucokinase activity											RHEA:11460|Reactome:R-HSA-5696021|EC:2.7.1.147		molecular_function											owl:Class	
GO:0007277	biolink:NamedThing	pole cell development	The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0001660	biolink:NamedThing	fever generation	The heat generation process that results in a rise in body temperature above the normal, often as a response to infection.	got7fsn_ti	pyrexia											Wikipedia:Fever		biological_process											owl:Class	
GO:0031649	biolink:NamedThing	heat generation	Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.	got7fsn_ti														biological_process											owl:Class	
GO:0018011	biolink:NamedThing	N-terminal peptidyl-alanine methylation	The methylation of the N-terminal alanine of proteins.	got7fsn_ti												RESID:AA0061|RESID:AA0062		biological_process											owl:Class	
GO:0098912	biolink:NamedThing	membrane depolarization during atrial cardiac muscle cell action potential	The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti	electrocardiogram PR interval|atrial cardiac muscle cell depolarization|atrial depolarization													biological_process											owl:Class	
GO:0086012	biolink:NamedThing	membrane depolarization during cardiac muscle cell action potential	The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti							tb	2011-11-10T08:20:33Z						biological_process											owl:Class	
GO:0090031	biolink:NamedThing	positive regulation of steroid hormone biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.	got7fsn_ti							tb	2009-08-03T10:40:32Z						biological_process											owl:Class	
GO:0044818	biolink:NamedThing	mitotic G2/M transition checkpoint	A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.	got7fsn_ti							jl	2013-11-19T14:20:00Z						biological_process											owl:Class	
GO:0080192	biolink:NamedThing	primary thickening	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem.	got7fsn_ti					Occurs in shoot axes and rarely in roots in many monocotyledons.		dhl	2012-12-06T15:55:18Z						biological_process											owl:Class	
GO:0002766	biolink:NamedThing	innate immune response-inhibiting signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.	got7fsn_ti														biological_process											owl:Class	
GO:0002765	biolink:NamedThing	immune response-inhibiting signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response.	got7fsn_ti														biological_process											owl:Class	
GO:1900799	biolink:NamedThing	cordyol C biosynthetic process	The chemical reactions and pathways resulting in the formation of cordyol C.	got7fsn_ti	cordyol C synthesis|cordyol C anabolism|cordyol C biosynthesis|cordyol C formation						di	2012-06-04T09:48:17Z						biological_process											owl:Class	
GO:0097591	biolink:NamedThing	ventral disc lateral crest	Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet.	got7fsn_ti	ventral disk lateral crest|lateral crest				Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T10:47:48Z						cellular_component											owl:Class	
GO:0043711	biolink:NamedThing	pilus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies.	got7fsn_ti	pilus organization and biogenesis|pilus organisation				Note that this term should not be used for direct annotation. Please use one of the children, GO:0009297 ; pilus assembly or GO:0043108 ; pilus retraction.									biological_process											owl:Class	
GO:0071352	biolink:NamedThing	cellular response to interleukin-2	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.	got7fsn_ti	cellular response to IL-2						mah	2009-12-11T02:50:48Z						biological_process											owl:Class	
GO:0038134	biolink:NamedThing	ERBB2-EGFR signaling pathway	A series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.	got7fsn_ti	EGFR-HER2 signaling pathway|ERBB2-EGFR signalling pathway						bf	2012-03-30T11:16:28Z						biological_process											owl:Class	
GO:0038128	biolink:NamedThing	ERBB2 signaling pathway	A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.	got7fsn_ti	receptor tyrosine-protein kinase erbB-2 signaling pathway|HER2 signaling pathway|ERBB2 signalling pathway|NEU signaling						bf	2012-03-30T10:05:12Z						biological_process											owl:Class	
GO:0140593	biolink:NamedThing	host apoplast	The apoplast region surrounding a host plant cell. Plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	host cell apoplast	https://github.com/geneontology/go-ontology/issues/21343|https://github.com/geneontology/go-ontology/issues/20814					pg	2021-02-09T18:56:11Z						cellular_component											owl:Class	
GO:0033258	biolink:NamedThing	plastid DNA metabolic process	The chemical reactions and pathways involving plastid DNA.	got7fsn_ti	plastid DNA metabolism													biological_process											owl:Class	
GO:0001713	biolink:NamedThing	ectodermal cell fate determination	The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	ectoderm cell fate determination													biological_process											owl:Class	
GO:0047179	biolink:NamedThing	platelet-activating factor acetyltransferase activity	Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid.	got7fsn_ti	PAF acetyltransferase activity|1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phospholipid acetyltransferase activity											MetaCyc:2.3.1.149-RXN|RHEA:11048|EC:2.3.1.149		molecular_function											owl:Class	
GO:0102597	biolink:NamedThing	3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity	Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin E + NADP + H2O.	got7fsn_ti												EC:1.14.14.122|RHEA:41468|MetaCyc:RXN-15381		molecular_function											owl:Class	
GO:1990537	biolink:NamedThing	mitotic spindle polar microtubule	Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone.	got7fsn_ti							vw	2014-11-14T15:32:38Z						cellular_component											owl:Class	
GO:1990498	biolink:NamedThing	mitotic spindle microtubule	Any microtubule that is part of a mitotic spindle; anchored at one spindle pole.	got7fsn_ti							vw	2014-09-26T13:34:40Z						cellular_component											owl:Class	
GO:0008870	biolink:NamedThing	galactoside O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside.	got7fsn_ti	thiogalactoside acetyltransferase activity|acetyl-CoA:beta-D-galactoside 6-acetyltransferase activity|galactoside acetyltransferase activity|thiogalactoside transacetylase activity											MetaCyc:GALACTOACETYLTRAN-RXN|EC:2.3.1.18|RHEA:15713		molecular_function											owl:Class	
GO:0030944	biolink:NamedThing	DDEL sequence binding	Binding to a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.	got7fsn_ti														molecular_function											owl:Class	
GO:0046923	biolink:NamedThing	ER retention sequence binding	Binding to an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER.	got7fsn_ti	endoplasmic reticulum retention sequence binding													molecular_function											owl:Class	
GO:0097141	biolink:NamedThing	BIM-BCL-2 complex	A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:42:31Z						cellular_component											owl:Class	
GO:0061952	biolink:NamedThing	midbody abscission	The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells.	got7fsn_ti	cytokinetic abscission|cell separation during cytokinesis						dph	2017-11-07T19:44:37Z						biological_process											owl:Class	
GO:0010738	biolink:NamedThing	regulation of protein kinase A signaling	Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	regulation of protein kinase A signaling cascade|regulation of protein kinase A signalling cascade|regulation of PKA signaling cascade													biological_process											owl:Class	
GO:1902531	biolink:NamedThing	regulation of intracellular signal transduction	Any process that modulates the frequency, rate or extent of intracellular signal transduction.	got7fsn_ti	regulation of intracellular signaling cascade|regulation of intracellular protein kinase cascade|regulation of signal transduction via intracellular signaling cascade|regulation of intracellular signaling pathway|regulation of intracellular signal transduction pathway|regulation of signal transmission via intracellular cascade|regulation of intracellular signaling chain						bf	2013-12-02T11:32:52Z			GO:0010627			biological_process											owl:Class	
GO:0000170	biolink:NamedThing	sphingosine hydroxylase activity	Catalysis of the hydroxylation of sphingolipid long chain bases.	got7fsn_ti												Reactome:R-HSA-428260		molecular_function											owl:Class	
GO:0030585	biolink:NamedThing	phosphoenolpyruvate carboxykinase (diphosphate) activity	Catalysis of the reaction: diphosphate + oxaloacetate = CO(2) + phosphate + phosphoenolpyruvate.	got7fsn_ti	phosphoenolpyruvic carboxykinase (pyrophosphate)|phosphopyruvate carboxylase (pyrophosphate)|phosphoenolpyruvate carboxytransphosphorylase activity|diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)|phosphoenolpyruvate carboxykinase (pyrophosphate) activity|phosphoenolpyruvate carboxyphosphotransferase activity|phosphoenolpyruvate carboxylase (pyrophosphate)|phosphopyruvate carboxykinase|phosphopyruvate carboxykinase (pyrophosphate)|PEP carboxyphosphotransferase activity|phosphoenolpyruvic carboxytransphosphorylase activity|phosphoenolpyruvic carboxylase (pyrophosphate)|PEPCTrP|phosphoenolpyruvic carboxykinase|diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)											RHEA:22356|KEGG_REACTION:R00346|MetaCyc:4.1.1.38-RXN|EC:4.1.1.38		molecular_function											owl:Class	
GO:0060323	biolink:NamedThing	head morphogenesis	The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.	got7fsn_ti														biological_process											owl:Class	
GO:0032935	biolink:NamedThing	sterol sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of a sterol.	got7fsn_ti	sterol-sensing domain													molecular_function											owl:Class	
GO:0032934	biolink:NamedThing	sterol binding	Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.	got7fsn_ti	sterol carrier activity										GO:0005498			molecular_function											owl:Class	
GO:0018730	biolink:NamedThing	glutaconate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA.	got7fsn_ti	acetyl-CoA:(E)-glutaconate CoA-transferase activity											EC:2.8.3.12|RHEA:23208|UM-BBD_reactionID:r0085|MetaCyc:GLUTACONATE-COA-TRANSFERASE-RXN		molecular_function											owl:Class	
GO:0018010	biolink:NamedThing	glycoprotein N-palmitoyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein.	got7fsn_ti	palmitoyl-CoA:glycoprotein N-palmitoyltransferase activity|mucus glycoprotein fatty acyltransferase											MetaCyc:GLYCOPROTEIN-N-PALMITOYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0048542	biolink:NamedThing	lymph gland development	The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.	got7fsn_ti	haematopoietic organ development|hemopoietic organ development|hematopoietic organ development|haemopoietic organ development													biological_process											owl:Class	
GO:1990672	biolink:NamedThing	medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane	The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport.	got7fsn_ti							bhm	2015-03-02T11:34:39Z						biological_process											owl:Class	
GO:0007134	biolink:NamedThing	meiotic telophase I	The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0004637	biolink:NamedThing	phosphoribosylamine-glycine ligase activity	Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H(+) + phosphate.	got7fsn_ti	phosphoribosylglycineamide synthetase activity|glycineamide ribonucleotide synthetase activity|5'-phosphoribosylglycinamide synthetase activity|GARS activity|GAR synthetase activity|phosphoribosylglycinamide synthetase activity|GAR|2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity|glycinamide ribonucleotide synthetase activity|5-phospho-D-ribosylamine:glycine ligase (ADP-forming)											MetaCyc:GLYRIBONUCSYN-RXN|EC:6.3.4.13|RHEA:17453|Reactome:R-HSA-73814|KEGG_REACTION:R04144		molecular_function											owl:Class	
GO:0140403	biolink:NamedThing	effector-mediated suppression of host innate immune response	A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	effector-triggered suppression of host immune innate response by symbiont|effector-mediated suppression of host innate immune response by symbiont|effector triggered suppression of host immune innate response by symbiont|effector-mediated suppression of host immune innate response by symbiont|effector-dependent suppression of host immune innate response by symbiont|effector-mediated suppression of host innate immunity|effector dependent suppression of host immune innate response by symbiont						pg	2019-12-05T11:34:55Z						biological_process											owl:Class	
GO:0043648	biolink:NamedThing	dicarboxylic acid metabolic process	The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).	got7fsn_ti	dicarboxylic acid metabolism|dicarboxylate metabolism|dicarboxylate metabolic process													biological_process											owl:Class	
GO:0106167	biolink:NamedThing	extracellular ATP signaling	A series of molecular signals mediated by the detection of extracellular ATP.	got7fsn_ti							hjd	2019-02-06T19:21:44Z						biological_process											owl:Class	
GO:0071318	biolink:NamedThing	cellular response to ATP	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.	got7fsn_ti	cellular response to adenosine triphosphate|cellular response to adenosine 5'-triphosphate						mah	2009-12-10T05:09:47Z						biological_process											owl:Class	
GO:0042579	biolink:NamedThing	microbody	Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).	got7fsn_ti												Wikipedia:Microbody		cellular_component											owl:Class	
GO:0008408	biolink:NamedThing	3'-5' exonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.	got7fsn_ti	3'-5'-exonuclease activity											Reactome:R-HSA-3245943		molecular_function											owl:Class	
GO:0061253	biolink:NamedThing	mesonephric glomerular parietal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	got7fsn_ti							dph	2010-08-30T01:26:47Z						biological_process											owl:Class	
GO:0072139	biolink:NamedThing	glomerular parietal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	got7fsn_ti							mah	2010-02-24T01:33:05Z						biological_process											owl:Class	
GO:0072232	biolink:NamedThing	metanephric proximal convoluted tubule segment 2 development	The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride.	got7fsn_ti	metanephric S2 development						mah	2010-03-18T03:39:28Z						biological_process											owl:Class	
GO:0072032	biolink:NamedThing	proximal convoluted tubule segment 2 development	The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.	got7fsn_ti	S2 development						mah	2010-01-25T02:56:36Z						biological_process											owl:Class	
GO:0004621	biolink:NamedThing	glycosylphosphatidylinositol phospholipase D activity	Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol.	got7fsn_ti	phosphatidylinositol phospholipase D activity|glycoprotein-phosphatidylinositol phosphatidohydrolase activity|phosphatidylinositol-specific phospholipase D activity|GPI-PLD activity|phosphatidylinositol-glycan-specific phospholipase D activity|glycoprotein phospholipase D activity											RHEA:10832|MetaCyc:GLYCOPROTEIN-PHOSPHOLIPASE-D-RXN|EC:3.1.4.50|Reactome:R-HSA-8940388		molecular_function											owl:Class	
GO:0004630	biolink:NamedThing	phospholipase D activity	Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.	got7fsn_ti	choline phosphatase activity|lipophosphodiesterase II activity|phosphatidylcholine phosphatidohydrolase activity|lecithinase D activity											EC:3.1.4.4|MetaCyc:PHOSCHOL-RXN|RHEA:14445|Reactome:R-HSA-1483182|Reactome:R-HSA-1483142|Reactome:R-HSA-2029471		molecular_function											owl:Class	
GO:0110071	biolink:NamedThing	cellularization cleavage furrow invagination front	The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14543					kmv	2017-11-22T20:13:21Z						cellular_component											owl:Class	
GO:0000338	biolink:NamedThing	protein deneddylation	The removal of a ubiquitin-like protein of the NEDD8 type from a protein.	got7fsn_ti	cullin deneddylation										GO:0010388			biological_process											owl:Class	
GO:0018269	biolink:NamedThing	GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GPI anchor formation via N-seryl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-seryl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-seryl-glycosylphosphatidylinositolethanolamine											RESID:AA0162		biological_process											owl:Class	
GO:0050871	biolink:NamedThing	positive regulation of B cell activation	Any process that activates or increases the frequency, rate or extent of B cell activation.	got7fsn_ti	up regulation of B cell activation|positive regulation of B-cell activation|activation of B cell activation|stimulation of B cell activation|positive regulation of B-lymphocyte activation|positive regulation of B lymphocyte activation|upregulation of B cell activation|up-regulation of B cell activation													biological_process											owl:Class	
GO:0102883	biolink:NamedThing	(+)-beta-chamigrene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-chamigrene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8424|EC:4.2.3.78|RHEA:30379		molecular_function											owl:Class	
GO:0043626	biolink:NamedThing	PCNA complex	A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation.	got7fsn_ti	sliding clamp|PCNA homotrimer|proliferating cell nuclear antigen complex													cellular_component											owl:Class	
GO:0044796	biolink:NamedThing	DNA polymerase processivity factor complex	A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication.	got7fsn_ti							jl	2013-08-28T11:16:14Z						cellular_component											owl:Class	
GO:0061518	biolink:NamedThing	microglial cell proliferation	The expansion of a microglial cell population by cell division.	got7fsn_ti							dph	2013-04-18T13:20:21Z						biological_process											owl:Class	
GO:0047170	biolink:NamedThing	glucarate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA.	got7fsn_ti	sinapoyl-CoA:glucarate O-(hydroxycinnamoyl)transferase activity											KEGG_REACTION:R02899|RHEA:23308|MetaCyc:2.3.1.131-RXN|EC:2.3.1.131		molecular_function											owl:Class	
GO:0050737	biolink:NamedThing	O-hydroxycinnamoyltransferase activity	Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0008459	biolink:NamedThing	chondroitin 6-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.	got7fsn_ti	3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase activity|terminal 6-sulfotransferase activity|chondroitin 6-O-sulfotransferase activity|chondroitin 6-sulphotransferase activity|3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase activity											RHEA:11108|Reactome:R-HSA-2018682|EC:2.8.2.17|MetaCyc:CHONDROITIN-6-SULFOTRANSFERASE-RXN|Reactome:R-HSA-3595175		molecular_function											owl:Class	
GO:0034481	biolink:NamedThing	chondroitin sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate.	got7fsn_ti														molecular_function											owl:Class	
GO:0071103	biolink:NamedThing	DNA conformation change	A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.	got7fsn_ti	DNA conformation modification						mah	2009-11-09T11:36:34Z						biological_process											owl:Class	
GO:0044639	biolink:NamedThing	envenomation resulting in modulation of complement activation, lectin pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism.	got7fsn_ti	envenomation resulting in regulation of complement activation, lectin pathway in other organism						jl	2012-07-05T04:53:36Z						biological_process											owl:Class	
GO:0044646	biolink:NamedThing	envenomation resulting in modulation of complement activation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism.	got7fsn_ti	envenomation resulting in regulation of complement activation in other organism						jl	2012-07-11T12:49:28Z						biological_process											owl:Class	
GO:0018156	biolink:NamedThing	peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine	The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine).	got7fsn_ti												RESID:AA0112		biological_process											owl:Class	
GO:0001111	biolink:NamedThing	promoter clearance from RNA polymerase II promoter	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.	got7fsn_ti	promoter escape from RNA polymerase II promoter						krc	2010-12-01T03:09:31Z						biological_process											owl:Class	
GO:0001109	biolink:NamedThing	promoter clearance during DNA-templated transcription	Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.	got7fsn_ti	promoter escape|promoter clearance during DNA-dependent transcription						krc	2010-12-01T02:13:09Z						biological_process											owl:Class	
GO:0001666	biolink:NamedThing	response to hypoxia	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	got7fsn_ti	response to sustained hypoxia|response to lowered oxygen tension|response to intermittent hypoxia|response to hypoxic stress				Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.									biological_process											owl:Class	
GO:0021991	biolink:NamedThing	neural plate thickening	The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.	got7fsn_ti														biological_process											owl:Class	
GO:0022850	biolink:NamedThing	serotonin-gated cation-selective channel activity	Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	serotonin-gated cation channel activity|5-hydroxytryptamine-gated receptor-channel|serotonin-activated cation-selective channel activity				Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'G protein-coupled serotonin receptor activity ; GO:0004993'.						GO:0005232	Reactome:R-HSA-975311|Reactome:R-HSA-9648983		molecular_function											owl:Class	
GO:0048802	biolink:NamedThing	notum morphogenesis	The process in which the anatomical structures of the dorsal part of the body are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0070138	biolink:NamedThing	ubiquitin-like protein-specific isopeptidase activity	Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated.	got7fsn_ti	small conjugating protein-specific isopeptidase activity													molecular_function											owl:Class	
GO:0002639	biolink:NamedThing	positive regulation of immunoglobulin production	Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.	got7fsn_ti	activation of immunoglobulin production|positive regulation of immunoglobulin biosynthetic process|positive regulation of immunoglobulin secretion|up regulation of immunoglobulin production|up-regulation of immunoglobulin production|stimulation of immunoglobulin production|upregulation of immunoglobulin production										GO:0002642|GO:0051024			biological_process											owl:Class	
GO:0019726	biolink:NamedThing	mevaldate reductase (NADPH) activity	Catalysis of the reaction: (R)-mevalonate + NADP(+) = H(+) + mevaldate + NADPH.	got7fsn_ti	mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase|(R)-mevalonate:NADP+ oxidoreductase											MetaCyc:MEVALDATE-REDUCTASE-NADPH-RXN|RHEA:20193|KEGG_REACTION:R02247|EC:1.1.1.33		molecular_function											owl:Class	
GO:0006968	biolink:NamedThing	cellular defense response	A defense response that is mediated by cells.	got7fsn_ti	intracellular defence response|intracellular defense response|cellular defence response	https://github.com/geneontology/go-ontology/issues/18111									GO:0002818|GO:0016067|GO:0016066			biological_process											owl:Class	
GO:0000431	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter by galactose	Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti														biological_process											owl:Class	
GO:0036198	biolink:NamedThing	dTMP salvage	Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis.	got7fsn_ti	deoxythymidine monophosphate biosynthesis via salvage pathway|dTMP biosynthesis via salvage pathway						bf	2012-04-20T10:33:28Z				UniPathway:UPA00578		biological_process											owl:Class	
GO:0070266	biolink:NamedThing	necroptotic process	A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.	got7fsn_ti	TNF-induced necroptosis|activation of necroptosis by extracellular signals|induction of necroptosis by extracellular signals|PARP-dependent cell death|extracellular signal-induced necroptosis|necroptosis|establishment of necroptosis of activated-T cells|activation of necroptosis of activated-T cells|induction of necroptosis of activated-T cells|programmed necrotic cell death|activation of necroptosis in response to extracellular signals|parthanatos|induction of necroptosis|programmed necrosis|establishment of necroptosis|activation of necroptosis|RIPK1-mediated regulated necrosis				Examples of this are Birc2 and Birc3 (UniProt symbols Q62210 and O08863) in PMID:21052097.						GO:0060554|GO:0060553|GO:0060555			biological_process											owl:Class	
GO:0097300	biolink:NamedThing	programmed necrotic cell death	A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.	got7fsn_ti	programmed cell death by necrosis|regulated necrosis				This term may be used when annotating instances of programmed cell death characterized by necrotic morphology where the involvement of RIPK1 and/or RIPK3 is not shown. See PMID:23818611 for some examples.		pr	2012-05-04T03:03:39Z						biological_process											owl:Class	
GO:0070031	biolink:NamedThing	alphav-beta5 integrin-osteopontin complex	A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin.	got7fsn_ti	ITGAV-ITGB5-SPP1 complex													cellular_component											owl:Class	
GO:0001095	biolink:NamedThing	TFIIE-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIIE complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	got7fsn_ti	TFIIE-class transcription factor binding						krc	2010-10-28T02:49:20Z						molecular_function											owl:Class	
GO:0005942	biolink:NamedThing	phosphatidylinositol 3-kinase complex	A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.	got7fsn_ti	PIK3CA-PIK3R1 complex|PI3K complex|phosphoinositide 3-kinase complex|1-phosphatidylinositol 3-kinase complex|PIK3C3-PIK3R4 complex|PI3-kinase p85-subunit alpha- PI3-kinase p110 complex				For discussion of membrane association, please see https://sourceforge.net/p/geneontology/ontology-requests/11559/									cellular_component											owl:Class	
GO:0099077	biolink:NamedThing	histone-dependent DNA binding	DNA-binding activity that is dependent on binding to a histone.	got7fsn_ti														molecular_function											owl:Class	
GO:0019981	biolink:NamedThing	interleukin-6 binding	Binding to interleukin-6.	got7fsn_ti	IL-6 binding													molecular_function											owl:Class	
GO:0009629	biolink:NamedThing	response to gravity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.	got7fsn_ti	response to gravitational stimulus													biological_process											owl:Class	
GO:0098572	biolink:NamedThing	stromal side of plastid thylakoid membrane	The side (leaflet) of the plastid thylakoid membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.	got7fsn_ti														cellular_component											owl:Class	
GO:0050842	biolink:NamedThing	copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide	The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.	got7fsn_ti												RESID:AA0355		biological_process											owl:Class	
GO:0018427	biolink:NamedThing	copper incorporation into metallo-sulfur cluster	The incorporation of copper into a metallo-sulfur cluster.	got7fsn_ti	copper incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0055070	biolink:NamedThing	copper ion homeostasis	Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.	got7fsn_ti	copper homeostasis													biological_process											owl:Class	
GO:0061683	biolink:NamedThing	branching involved in seminal vesicle morphogenesis	The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.	got7fsn_ti	seminal vesicle branching morphogenesis|gonecyst branching morphogenesis|seminal gland branching morphogenesis|seminal vesicle branching						dph	2015-03-04T13:39:47Z						biological_process											owl:Class	
GO:0035247	biolink:NamedThing	peptidyl-arginine omega-N-methylation	The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.	got7fsn_ti												RESID:AA0068|RESID:AA0069|RESID:AA0067		biological_process											owl:Class	
GO:0035246	biolink:NamedThing	peptidyl-arginine N-methylation	The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0000155	biolink:NamedThing	phosphorelay sensor kinase activity	Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.	got7fsn_ti	two-component sensor activity|two-component system sensor activity|two-component sensor molecule											EC:2.7.3.-		molecular_function											owl:Class	
GO:0034835	biolink:NamedThing	2-mercaptobenzothiazole monooxygenase activity	Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole.	got7fsn_ti												UM-BBD_reactionID:r1178|EC:1.13.12.-		molecular_function											owl:Class	
GO:0032896	biolink:NamedThing	palmitoyl-CoA 9-desaturase activity	Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O.	got7fsn_ti	palmitoyl-CoA delta9-desaturase acitivity													molecular_function											owl:Class	
GO:0034797	biolink:NamedThing	fosfomycin 2-glutathione ligase activity	Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.	got7fsn_ti												UM-BBD_reactionID:r1073		molecular_function											owl:Class	
GO:0016877	biolink:NamedThing	ligase activity, forming carbon-sulfur bonds	Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti	ligase activity, forming carbon-sulphur bonds											EC:6.2.-.-		molecular_function											owl:Class	
GO:0048170	biolink:NamedThing	positive regulation of long-term neuronal synaptic plasticity	A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.	got7fsn_ti	up-regulation of long-term neuronal synaptic plasticity|stimulation of long-term neuronal synaptic plasticity|up regulation of long-term neuronal synaptic plasticity|activation of long-term neuronal synaptic plasticity|upregulation of long-term neuronal synaptic plasticity				Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:0050769	biolink:NamedThing	positive regulation of neurogenesis	Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.	got7fsn_ti	up regulation of neurogenesis|up-regulation of neurogenesis|activation of neurogenesis|upregulation of neurogenesis|stimulation of neurogenesis													biological_process											owl:Class	
GO:0008887	biolink:NamedThing	glycerate kinase activity	Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+).	got7fsn_ti	D-glycerate kinase activity|ATP:(R)-glycerate 3-phosphotransferase activity|D-glycerate 3-kinase activity|glycerate-3-kinase activity|glycerate kinase (phosphorylating)|GK|ATP:D-glycerate 2-phosphotransferase activity|D-glyceric acid kinase activity											RHEA:23516|KEGG_REACTION:R01514|MetaCyc:GLY3KIN-RXN|EC:2.7.1.31|Reactome:R-HSA-6799495		molecular_function											owl:Class	
GO:0061514	biolink:NamedThing	interleukin-34-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-34 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti							dph	2013-04-18T13:00:33Z						biological_process											owl:Class	
GO:0062160	biolink:NamedThing	spongiome	A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory.	got7fsn_ti							dph	2019-09-26T14:30:41Z						cellular_component											owl:Class	
GO:0003319	biolink:NamedThing	cardioblast migration to the midline involved in heart rudiment formation	The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment.	got7fsn_ti							dph	2009-10-27T09:21:36Z						biological_process											owl:Class	
GO:0033745	biolink:NamedThing	L-methionine-(R)-S-oxide reductase activity	Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.	got7fsn_ti	free met-R-(o) reductase activity|free-methionine (R)-S-oxide reductase activity|FRMsr|L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming] activity											EC:1.8.4.14|RHEA:21260|MetaCyc:1.8.4.14-RXN		molecular_function											owl:Class	
GO:0034326	biolink:NamedThing	butanoyltransferase activity	Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0051787	biolink:NamedThing	misfolded protein binding	Binding to a misfolded protein.	got7fsn_ti												Reactome:R-HSA-5324632		molecular_function											owl:Class	
GO:0044841	biolink:NamedThing	gut granule membrane	The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.	got7fsn_ti							jl	2014-03-25T12:02:05Z						cellular_component											owl:Class	
GO:0014898	biolink:NamedThing	cardiac muscle hypertrophy in response to stress	The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.	got7fsn_ti														biological_process											owl:Class	
GO:0008915	biolink:NamedThing	lipid-A-disaccharide synthase activity	Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP.	got7fsn_ti	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-beta-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase activity											RHEA:22668|EC:2.4.1.182|MetaCyc:LIPIDADISACCHARIDESYNTH-RXN|KEGG_REACTION:R04606		molecular_function											owl:Class	
GO:0070195	biolink:NamedThing	growth hormone receptor complex	A receptor complex that consists of two identical subunits and binds growth hormone.	got7fsn_ti														cellular_component											owl:Class	
GO:0034844	biolink:NamedThing	naphthyl-2-methyl-succinate CoA-transferase activity	Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate.	got7fsn_ti												UM-BBD_reactionID:r1256		molecular_function											owl:Class	
GO:0006740	biolink:NamedThing	NADPH regeneration	A metabolic process that generates a pool of NADPH by the reduction of NADP+.	got7fsn_ti	reduced NADP regeneration|reduced nicotinamide adenine dinucleotide phosphate regeneration|NADP (reduced) regeneration													biological_process											owl:Class	
GO:0006739	biolink:NamedThing	NADP metabolic process	The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.	got7fsn_ti	reduced nicotinamide adenine dinucleotide phosphate metabolic process|NADPH metabolic process|nicotinamide adenine dinucleotide phosphate metabolism|NADP metabolism|NADP (oxidized) metabolic process|oxidized NADP metabolic process|reduced NADP metabolic process|nicotinamide adenine dinucleotide phosphate metabolic process|NADP (oxidized) metabolism|reduced NADP metabolism|oxidized nicotinamide adenine dinucleotide phosphate metabolic process|NADPH metabolism|oxidized nicotinamide adenine dinucleotide phosphate metabolism|reduced nicotinamide adenine dinucleotide phosphate metabolism|NAD phosphorylation and dephosphorylation|NADP (reduced) metabolism|oxidized NADP metabolism|NADP (reduced) metabolic process													biological_process											owl:Class	
GO:0097485	biolink:NamedThing	neuron projection guidance	The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.	got7fsn_ti	neuron process guidance|neuron protrusion guidance|neurite guidance|neuronal cell projection guidance						pr	2013-07-08T13:32:37Z						biological_process											owl:Class	
GO:0070625	biolink:NamedThing	zymogen granule exocytosis	The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.	got7fsn_ti							mah	2009-05-01T03:56:02Z						biological_process											owl:Class	
GO:0120127	biolink:NamedThing	response to zinc ion starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion.	got7fsn_ti							krc	2018-02-12T19:57:02Z						biological_process											owl:Class	
GO:0004649	biolink:NamedThing	poly(ADP-ribose) glycohydrolase activity	Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.	got7fsn_ti												Reactome:R-HSA-5651828|RHEA:52216|MetaCyc:3.2.1.143-RXN|EC:3.2.1.143|Reactome:R-HSA-8952903		molecular_function											owl:Class	
GO:0018702	biolink:NamedThing	1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity	Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.	got7fsn_ti	DDE dehalogenase activity|1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene dehalogenase activity											UM-BBD_reactionID:r0440|EC:1.97.1.-		molecular_function											owl:Class	
GO:0071628	biolink:NamedThing	intrinsic component of fungal-type vacuolar membrane	The component of a fungal-type vacuole membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti							mah	2010-02-10T03:53:00Z						cellular_component											owl:Class	
GO:0031310	biolink:NamedThing	intrinsic component of vacuolar membrane	The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to vacuolar membrane													cellular_component											owl:Class	
GO:0022622	biolink:NamedThing	root system development	The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0072299	biolink:NamedThing	negative regulation of metanephric glomerulus development	Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.	got7fsn_ti							mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:0072217	biolink:NamedThing	negative regulation of metanephros development	Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti							mah	2010-03-18T01:45:48Z						biological_process											owl:Class	
GO:0052386	biolink:NamedThing	cell wall thickening	A type of cell wall modification in which the cell wall is reinforced and made thicker.	got7fsn_ti														biological_process											owl:Class	
GO:1990592	biolink:NamedThing	protein K69-linked ufmylation	A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.	got7fsn_ti							jl	2014-12-15T17:01:23Z						biological_process											owl:Class	
GO:1990564	biolink:NamedThing	protein polyufmylation	Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain.	got7fsn_ti							jl	2014-11-26T14:15:36Z						biological_process											owl:Class	
GO:0050175	biolink:NamedThing	phenylalanine dehydrogenase activity	Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH.	got7fsn_ti	L-phenylalanine dehydrogenase activity|PheDH activity|L-phenylalanine:NAD+ oxidoreductase (deaminating)|PHD											EC:1.4.1.20|RHEA:21408|MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0008176	biolink:NamedThing	tRNA (guanine-N7-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.	got7fsn_ti	transfer ribonucleate guanine 7-methyltransferase activity|tRNA guanine 7-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase activity|7-methylguanine transfer ribonucleate methylase activity|N7-methylguanine methylase activity|S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase activity											Reactome:R-HSA-6782286|RHEA:42708|MetaCyc:TRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|EC:2.1.1.33		molecular_function											owl:Class	
GO:0010030	biolink:NamedThing	positive regulation of seed germination	Any process that activates or increase the rate of seed germination.	got7fsn_ti	up regulation of seed germination|activation of seed germination|up-regulation of seed germination|upregulation of seed germination|stimulation of seed germination													biological_process											owl:Class	
GO:0048582	biolink:NamedThing	positive regulation of post-embryonic development	Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.	got7fsn_ti	up regulation of post-embryonic development|activation of post-embryonic development|upregulation of post-embryonic development|stimulation of post-embryonic development|up-regulation of post-embryonic development													biological_process											owl:Class	
GO:0101006	biolink:NamedThing	protein histidine phosphatase activity	Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate.	got7fsn_ti	phosphohistidine phosphatase activity	https://github.com/geneontology/go-ontology/issues/21517			This eukaryotic enzyme dephosphorylates phosphorylated histidine residues within proteins and peptides. The enzyme acts on phosphate groups attached to both the pros- (RHEA:47964) and tele- (RHEA:47960) nitrogen atoms, but the pros- position is somewhat preferred (by a factor of two at the most) (EC:3.9.1.3).						GO:0008969	RHEA:47964|EC:3.9.1.3		molecular_function											owl:Class	
GO:0009110	biolink:NamedThing	vitamin biosynthetic process	The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	got7fsn_ti	vitamin formation|vitamin biosynthesis|vitamin synthesis|vitamin anabolism													biological_process											owl:Class	
GO:0006766	biolink:NamedThing	vitamin metabolic process	The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.	got7fsn_ti	vitamin metabolism													biological_process											owl:Class	
GO:0098733	biolink:NamedThing	hemidesmosome associated protein complex	Any protein complex that is part of or has some part in a hemidesmosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0019417	biolink:NamedThing	sulfur oxidation	The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur.	got7fsn_ti	sulphur oxidation													biological_process											owl:Class	
GO:0008239	biolink:NamedThing	dipeptidyl-peptidase activity	Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681										MetaCyc:3.4.14.4-RXN|EC:3.4.14.2|EC:3.4.14.4|EC:3.4.14.11|EC:3.4.14.5|MetaCyc:3.4.14.11-RXN|EC:3.4.14.1		molecular_function											owl:Class	
GO:0046885	biolink:NamedThing	regulation of hormone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.	got7fsn_ti	regulation of hormone synthesis|regulation of hormone biosynthesis|regulation of hormone anabolism|regulation of hormone formation													biological_process											owl:Class	
GO:0003248	biolink:NamedThing	heart capillary growth	The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle.	got7fsn_ti							dph	2009-10-13T11:53:12Z						biological_process											owl:Class	
GO:0097741	biolink:NamedThing	mastigoneme	A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum.	got7fsn_ti							pr	2016-10-19T11:33:38Z						cellular_component											owl:Class	
GO:0051308	biolink:NamedThing	male meiosis chromosome separation	The process in which paired chromosomes are physically detached from each other during male meiosis.	got7fsn_ti	male meiosis chromosome resolution|chromosome separation during male meiosis													biological_process											owl:Class	
GO:0007060	biolink:NamedThing	male meiosis chromosome segregation	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.	got7fsn_ti														biological_process											owl:Class	
GO:0032132	biolink:NamedThing	O6-alkylguanine-DNA binding	Binding to an O6-alkylguanine adduct in DNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0032131	biolink:NamedThing	alkylated DNA binding	Binding to an alkylated residue in DNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0035202	biolink:NamedThing	tracheal pit formation in open tracheal system	Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster.	got7fsn_ti	tracheal sac formation|tracheal placode invagination													biological_process											owl:Class	
GO:2001153	biolink:NamedThing	positive regulation of renal water transport	Any process that activates or increases the frequency, rate or extent of renal water transport.	got7fsn_ti							yaf	2011-10-24T11:38:01Z						biological_process											owl:Class	
GO:0030234	biolink:NamedThing	enzyme regulator activity	Binds to and modulates the activity of an enzyme.	got7fsn_ti	enzyme modulator|metalloenzyme regulator activity|catalytic regulator activity				This term should only be used in cases when the regulator directly interacts with the enzyme.						GO:0010576			molecular_function											owl:Class	
GO:0043334	biolink:NamedThing	2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	got7fsn_ti	2-hexaprenyl-6-methoxy-1,4-benzoquinone methylase activity				Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.									molecular_function											owl:Class	
GO:0050887	biolink:NamedThing	determination of sensory modality	The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain.	got7fsn_ti														biological_process											owl:Class	
GO:0050893	biolink:NamedThing	sensory processing	Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.	got7fsn_ti														biological_process											owl:Class	
GO:0102389	biolink:NamedThing	polyprenol reductase activity	Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol.	got7fsn_ti												MetaCyc:RXN-13604|RHEA:34279|EC:1.3.1.94		molecular_function											owl:Class	
GO:0048868	biolink:NamedThing	pollen tube development	The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0047816	biolink:NamedThing	D-arabinose 1-dehydrogenase (NAD+) activity	Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH.	got7fsn_ti	D-arabinose:NAD+ 1-oxidoreductase activity|NAD-pentose-dehydrogenase activity|arabinose(fucose)dehydrogenase activity											RHEA:20457|MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.116		molecular_function											owl:Class	
GO:0045290	biolink:NamedThing	D-arabinose 1-dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.	got7fsn_ti	D-arabinose:NAD(P)+ 1-oxidoreductase activity											MetaCyc:1.1.1.117-RXN|EC:1.1.1.117		molecular_function											owl:Class	
GO:0120318	biolink:NamedThing	olfactory sociosexual communication	The use of external chemical cues called pheromones to send social and sexual information between members of the same species, leading to specific behavioral responses. Pheromones may be detected by two olfactory sensory circuits, the main olfactory pathway and the vomeronasal system.	got7fsn_ti					Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior.		krc	2021-05-21T19:35:58Z						biological_process											owl:Class	
GO:0019391	biolink:NamedThing	glucuronoside catabolic process	The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.	got7fsn_ti	glucuronoside catabolism|glucuronoside degradation|glucuronoside breakdown|glucuronide catabolism|glucuronide catabolic process											MetaCyc:GLUCUROCAT-PWY		biological_process											owl:Class	
GO:0103102	biolink:NamedThing	UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate <=> H+ + 7-methylthioheptyldesulfoglucosinolate + UDP.	got7fsn_ti												EC:2.4.1.195|MetaCyc:RXNQT-4327		molecular_function											owl:Class	
GO:0002019	biolink:NamedThing	regulation of renal output by angiotensin	The process in which angiotensin directly modulates the rate of urine output by the kidney.	got7fsn_ti	angiotensin-mediated regulation of renal output|angiotensin mediated control of renal output|angiotensin mediated regulation of renal output													biological_process											owl:Class	
GO:0002016	biolink:NamedThing	regulation of blood volume by renin-angiotensin	The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood.	got7fsn_ti	renin-angiotensin regulation of blood volume|renin-angiotensin control of body fluid levels													biological_process											owl:Class	
GO:0019176	biolink:NamedThing	dihydroneopterin monophosphate phosphatase activity	Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate.	got7fsn_ti	dihydroneopterin monophosphate dephosphorylase activity											MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN|RHEA:25306		molecular_function											owl:Class	
GO:0001113	biolink:NamedThing	transcription open complex formation at RNA polymerase II promoter	Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.	got7fsn_ti	RNA polymerase II promoter melting|transcriptional open complex formation at RNA polymerase II promoter						krc	2010-12-02T02:27:19Z						biological_process											owl:Class	
GO:0000182	biolink:NamedThing	rDNA binding	Binding to a DNA sequence encoding a ribosomal RNA.	got7fsn_ti	ribosomal DNA binding													molecular_function											owl:Class	
GO:1990070	biolink:NamedThing	TRAPPI protein complex	A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast.	got7fsn_ti	TRAPP core complex						bhm	2013-03-28T14:04:40Z						cellular_component											owl:Class	
GO:0002461	biolink:NamedThing	tolerance induction dependent upon immune response	Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.	got7fsn_ti	immune response-dependent tolerance induction													biological_process											owl:Class	
GO:0005902	biolink:NamedThing	microvillus	Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.	got7fsn_ti	microvilli				Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta.							Wikipedia:Microvillus|NIF_Subcellular:sao671419673		cellular_component											owl:Class	
GO:0018418	biolink:NamedThing	nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide	The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.	got7fsn_ti	nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide											RESID:AA0		biological_process											owl:Class	
GO:0018414	biolink:NamedThing	nickel incorporation into metallo-sulfur cluster	The incorporation of nickel into a metallo-sulfur cluster.	got7fsn_ti	nickel incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0035013	biolink:NamedThing	myosuppressin receptor activity	Combining with the peptide myosuppressin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0039674	biolink:NamedThing	exit of virus from host cell nucleus	The directed movement of the viral genome or a viral particle out of the host cell nucleus.	got7fsn_ti							bf	2013-09-25T13:59:41Z				VZ:2177		biological_process											owl:Class	
GO:0102137	biolink:NamedThing	7-oxateasterone synthase activity	Catalysis of the reaction: H+ + teasterone + NADPH + O2 <=> 7-oxateasterone + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-11537		molecular_function											owl:Class	
GO:0090668	biolink:NamedThing	endothelial cell chemotaxis to vascular endothelial growth factor	The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF).	got7fsn_ti							tb	2015-12-15T11:31:43Z						biological_process											owl:Class	
GO:0090667	biolink:NamedThing	cell chemotaxis to vascular endothelial growth factor	The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF).	got7fsn_ti							tb	2015-12-15T11:27:12Z						biological_process											owl:Class	
GO:0047319	biolink:NamedThing	aspartate-phenylpyruvate transaminase activity	Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate.	got7fsn_ti	L-aspartate:phenylpyruvate aminotransferase activity|aspartate--phenylpyruvate aminotransferase activity|aspartate-phenylpyruvate aminotransferase activity											RHEA:14097|EC:2.6.1.70|KEGG_REACTION:R00695|MetaCyc:2.6.1.70-RXN		molecular_function											owl:Class	
GO:0018727	biolink:NamedThing	2-phenanthrol sulfotransferase activity	Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate.	got7fsn_ti	2-phenanthrol sulphotransferase activity											UM-BBD_reactionID:r0563		molecular_function											owl:Class	
GO:0075217	biolink:NamedThing	negative regulation of spore encystment on host	Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0075215	biolink:NamedThing	modulation of spore encystment on host	Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0032401	biolink:NamedThing	establishment of melanosome localization	The directed movement of a melanosome to a specific location.	got7fsn_ti	establishment of melanosome localisation													biological_process											owl:Class	
GO:0033545	biolink:NamedThing	myo-inositol hexakisphosphate biosynthetic process, lipid-dependent	The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C.	got7fsn_ti	myo-inositol hexakisphosphate synthesis, lipid-dependent|myo-inositol hexakisphosphate biosynthesis, lipid-dependent|phytate biosynthetic process, lipid-dependent|myo-inositol hexakisphosphate anabolism, lipid-dependent|phytate biosynthesis, lipid-dependent|myo-inositol hexakisphosphate formation, lipid-dependent											MetaCyc:PWY-6555		biological_process											owl:Class	
GO:0010264	biolink:NamedThing	myo-inositol hexakisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.	got7fsn_ti	myo-inositol hexakisphosphate formation|phytate biosynthetic process|myo-inositol hexakisphosphate synthesis|myo-inositol hexakisphosphate biosynthesis|phytate biosynthesis|myo-inositol hexakisphosphate anabolism													biological_process											owl:Class	
GO:0033447	biolink:NamedThing	AGA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AGA codon.	got7fsn_ti	arginine tRNA				Note that in the standard genetic code, AGA codes for arginine.									molecular_function											owl:Class	
GO:0008424	biolink:NamedThing	glycoprotein 6-alpha-L-fucosyltransferase activity	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+).	got7fsn_ti	guanosine diphosphofucose--glycoprotein fucosyltransferase activity|glycoprotein fucosyltransferase activity|GDPfucose-glycoprotein fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity|FucT|GDP-fucose--glycoprotein fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity|GDP-L-fucose--glycoprotein fucosyltransferase activity											EC:2.4.1.68|Reactome:R-HSA-1028788|KEGG_REACTION:R05988|Reactome:R-HSA-9696980|RHEA:12985|MetaCyc:2.4.1.68-RXN		molecular_function											owl:Class	
GO:0052866	biolink:NamedThing	phosphatidylinositol phosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate.	got7fsn_ti	phosphoinositide phosphatase activity						ai	2011-12-13T01:20:17Z						molecular_function											owl:Class	
GO:0042924	biolink:NamedThing	neuromedin U binding	Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses.	got7fsn_ti	NMU binding													molecular_function											owl:Class	
GO:0042923	biolink:NamedThing	neuropeptide binding	Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).	got7fsn_ti														molecular_function											owl:Class	
GO:0061559	biolink:NamedThing	cranial ganglion morphogenesis	The process in which the anatomical structure of a cranial ganglion is generated and organized.	got7fsn_ti	cranial ganglia morphogenesis						dph	2013-07-10T09:02:15Z						biological_process											owl:Class	
GO:0061552	biolink:NamedThing	ganglion morphogenesis	The process in which the anatomical structures of ganglion are generated and organized.	got7fsn_ti	ganglia morphogenesis						dph	2013-07-10T08:44:57Z						biological_process											owl:Class	
GO:0046886	biolink:NamedThing	positive regulation of hormone biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.	got7fsn_ti	stimulation of hormone biosynthetic process|positive regulation of hormone biosynthesis|positive regulation of hormone formation|upregulation of hormone biosynthetic process|up regulation of hormone biosynthetic process|up-regulation of hormone biosynthetic process|activation of hormone biosynthetic process|positive regulation of hormone anabolism|positive regulation of hormone synthesis													biological_process											owl:Class	
GO:0032352	biolink:NamedThing	positive regulation of hormone metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.	got7fsn_ti	up-regulation of hormone metabolic process|stimulation of hormone metabolic process|positive regulation of hormone metabolism|upregulation of hormone metabolic process|up regulation of hormone metabolic process|activation of hormone metabolic process													biological_process											owl:Class	
GO:0071421	biolink:NamedThing	manganese ion transmembrane transport	A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	manganese ion membrane transport|transmembrane manganese transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-12-15T02:41:31Z						biological_process											owl:Class	
GO:0006828	biolink:NamedThing	manganese ion transport	The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0002049	biolink:NamedThing	pyoverdine biosynthetic process	The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.	got7fsn_ti														biological_process											owl:Class	
GO:0008540	biolink:NamedThing	proteasome regulatory particle, base subcomplex	The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0070326	biolink:NamedThing	very-low-density lipoprotein particle receptor binding	Binding to a very-low-density lipoprotein receptor.	got7fsn_ti	VLDL receptor binding|VLDLR binding|apolipoprotein E receptor binding|very-low-density lipoprotein receptor binding													molecular_function											owl:Class	
GO:0070325	biolink:NamedThing	lipoprotein particle receptor binding	Binding to a lipoprotein particle receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0044053	biolink:NamedThing	translocation of peptides or proteins into host cell cytoplasm	The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm.	got7fsn_ti	transport of peptides or proteins into host cell cytoplasm|translocation of symbiont peptides or proteins into host cell cytoplasm													biological_process											owl:Class	
GO:0044355	biolink:NamedThing	clearance of foreign intracellular DNA	A defense process that protects an organism from invading foreign DNA.	got7fsn_ti	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	https://github.com/geneontology/go-ontology/issues/18727					jl	2011-08-11T11:25:43Z			GO:0044356			biological_process											owl:Class	
GO:0046283	biolink:NamedThing	anthocyanin-containing compound metabolic process	The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers.	got7fsn_ti	anthocyanin metabolism|anthocyanin metabolic process													biological_process											owl:Class	
GO:0009812	biolink:NamedThing	flavonoid metabolic process	The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.	got7fsn_ti	flavonoid metabolism													biological_process											owl:Class	
GO:0071260	biolink:NamedThing	cellular response to mechanical stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.	got7fsn_ti	cellular mechanical stimulus response						mah	2009-12-04T03:55:44Z						biological_process											owl:Class	
GO:0044278	biolink:NamedThing	cell wall disruption in other organism	A process carried out by an organism that results in the breakdown of the cell wall of a second organism.	got7fsn_ti							jl	2010-01-14T02:01:48Z						biological_process											owl:Class	
GO:2000273	biolink:NamedThing	positive regulation of signaling receptor activity	Any process that activates or increases the frequency, rate or extent of signaling receptor activity.	got7fsn_ti	positive regulation of signalling receptor activity						bf	2010-12-02T09:28:50Z						biological_process											owl:Class	
GO:0140289	biolink:NamedThing	protein mono-ADP-ribosylation	The transfer, from NAD, of a single (mono) ADP-ribose molecule to protein amino acids.	got7fsn_ti							pg	2018-11-22T13:52:54Z						biological_process											owl:Class	
GO:0000901	biolink:NamedThing	translation repressor activity, non-nucleic acid binding	Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0070677	biolink:NamedThing	rRNA (cytosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.	got7fsn_ti							mah	2009-05-29T03:37:53Z						molecular_function											owl:Class	
GO:0016434	biolink:NamedThing	rRNA (cytosine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.	got7fsn_ti														molecular_function											owl:Class	
GO:0051210	biolink:NamedThing	isotropic cell growth	The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth.	got7fsn_ti	uniform cell growth													biological_process											owl:Class	
GO:0005798	biolink:NamedThing	Golgi-associated vesicle	Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.	got7fsn_ti	Golgi vesicle|vesicular component				Note that this definition includes vesicles that are transiently associated with the Golgi.							NIF_Subcellular:sao819927218		cellular_component											owl:Class	
GO:0072195	biolink:NamedThing	kidney smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney.	got7fsn_ti							mah	2010-03-01T02:07:52Z						biological_process											owl:Class	
GO:0045551	biolink:NamedThing	cinnamyl-alcohol dehydrogenase activity	Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+.	got7fsn_ti	CAD activity|cinnamyl alcohol dehydrogenase activity|cinnamyl-alcohol:NADP+ oxidoreductase activity											EC:1.1.1.195|RHEA:10392|MetaCyc:CINNAMYL-ALCOHOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0002230	biolink:NamedThing	positive regulation of defense response to virus by host	Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.	got7fsn_ti	up-regulation of antiviral response by host|upregulation of antiviral response by host|up regulation of antiviral response by host|stimulation of antiviral response by host|activation of antiviral response by host|positive regulation of antiviral response by host													biological_process											owl:Class	
GO:0050691	biolink:NamedThing	regulation of defense response to virus by host	Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.	got7fsn_ti	regulation of antiviral response by host|host regulation of antiviral response|regulation by host of antiviral response													biological_process											owl:Class	
GO:0021584	biolink:NamedThing	pons formation	The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	got7fsn_ti														biological_process											owl:Class	
GO:0072635	biolink:NamedThing	interleukin-31 production	The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-31 production|interleukin-31 secretion										GO:0072636			biological_process											owl:Class	
GO:0102391	biolink:NamedThing	decanoate-CoA ligase activity	Catalysis of the reaction: ATP + decanoate + CoA = AMP +  diphosphate + decanoyl-CoA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18967										RHEA:33627|MetaCyc:RXN-13614		molecular_function											owl:Class	
GO:0004500	biolink:NamedThing	dopamine beta-monooxygenase activity	Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O.	got7fsn_ti	(3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity|4-(2-aminoethyl)pyrocatechol beta-oxidase activity|SDBH (soluble dopamine beta-monooxygenase)|3,4-dihydroxyphenethylamine beta-oxidase activity|oxygenase, dopamine beta-mono-|dopamine b-hydroxylase activity|3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)|dopamine beta-oxidase activity|dopa beta-hydroxylase activity|dopamine-B-hydroxylase activity|phenylamine beta-hydroxylase activity|dopamine hydroxylase activity|MDBH (membrane-associated dopamine beta-monooxygenase)|dopamine beta-hydroxylase activity											MetaCyc:DOPAMINE-BETA-MONOOXYGENASE-RXN|RHEA:19117|Reactome:R-HSA-209891|KEGG_REACTION:R02535|EC:1.14.17.1		molecular_function											owl:Class	
GO:0003684	biolink:NamedThing	damaged DNA binding	Binding to damaged DNA.	got7fsn_ti	DNA repair protein|DNA repair enzyme													molecular_function											owl:Class	
GO:0071174	biolink:NamedThing	mitotic spindle checkpoint signaling	A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.	got7fsn_ti	topoisomerase II checkpoint|mitotic spindle checkpoint|mitotic cell cycle spindle checkpoint|signal transduction involved in mitotic spindle checkpoint|topo II checkpoint|signal transduction involved in mitotic cell cycle spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20935			Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation checkpoints).		mah	2009-11-23T12:41:36Z			GO:0072477			biological_process											owl:Class	
GO:0080072	biolink:NamedThing	spermidine:sinapoyl CoA N-acyltransferase activity	Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule.	got7fsn_ti							dhl	2009-04-13T04:16:28Z						molecular_function											owl:Class	
GO:0010404	biolink:NamedThing	cell wall hydroxyproline-rich glycoprotein metabolic process	The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.	got7fsn_ti	cell wall hydroxyproline-rich glycoprotein metabolism													biological_process											owl:Class	
GO:0042134	biolink:NamedThing	rRNA primary transcript binding	Binding to an unprocessed ribosomal RNA transcript.	got7fsn_ti	pre-rRNA binding													molecular_function											owl:Class	
GO:0043133	biolink:NamedThing	hindgut contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0061556	biolink:NamedThing	trigeminal ganglion morphogenesis	The process in which the anatomical structure of a trigeminal ganglion is generated and organized.	got7fsn_ti	trigeminal ganglia morphogenesis						dph	2013-07-10T08:57:12Z						biological_process											owl:Class	
GO:0060402	biolink:NamedThing	calcium ion transport into cytosol	The directed movement of calcium ions (Ca2+) into the cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:0060401	biolink:NamedThing	cytosolic calcium ion transport	The directed movement of calcium ions (Ca2+) into, out of or within the cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:0018379	biolink:NamedThing	cytochrome c-heme linkage via heme-bis-L-cysteine	The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine.	got7fsn_ti	cytochrome c-haem linkage via haem-bis-L-cysteine											RESID:AA0134		biological_process											owl:Class	
GO:0000117	biolink:NamedThing	regulation of transcription involved in G2/M transition of mitotic cell cycle	Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter during G2/M transition of mitotic cell cycle|G2/M-specific transcription in mitotic cell cycle													biological_process											owl:Class	
GO:0120219	biolink:NamedThing	subapical part of cell	The region of a polarized cell that is just below the apical region. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue so the subapical region is further from the exposed surface and closer to the basal lamina.	got7fsn_ti	subapical region of cell						krc	2019-11-15T17:08:22Z						cellular_component											owl:Class	
GO:0042754	biolink:NamedThing	negative regulation of circadian rhythm	Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.	got7fsn_ti	down regulation of circadian rhythm|downregulation of circadian rhythm|down-regulation of circadian rhythm|inhibition of circadian rhythm													biological_process											owl:Class	
GO:0033989	biolink:NamedThing	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity	Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.	got7fsn_ti	46 kDa hydratase 2 activity|(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming] activity|D-3-hydroxyacyl-CoA dehydratase activity|(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase activity											Reactome:R-HSA-193535|EC:4.2.1.107|MetaCyc:4.2.1.107-RXN|Reactome:R-HSA-192331|RHEA:18933		molecular_function											owl:Class	
GO:0072081	biolink:NamedThing	specification of nephron tubule identity	The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity.	got7fsn_ti							mah	2010-02-01T02:42:34Z						biological_process											owl:Class	
GO:0045500	biolink:NamedThing	sevenless signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	sev receptor signaling pathway|sev signaling pathway|sevenless signalling pathway													biological_process											owl:Class	
GO:0007169	biolink:NamedThing	transmembrane receptor protein tyrosine kinase signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	transmembrane receptor protein tyrosine kinase signalling pathway													biological_process											owl:Class	
GO:0090524	biolink:NamedThing	cytochrome-b5 reductase activity, acting on NADH	Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5).	got7fsn_ti	cytochrome b5 reductase activity						tb	2013-01-11T12:21:50Z						molecular_function											owl:Class	
GO:0004128	biolink:NamedThing	cytochrome-b5 reductase activity, acting on NAD(P)H	Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5).	got7fsn_ti	reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase activity|cytochrome b5 reductase activity|dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase activity|NADH 5alpha-reductase activity|NADH-cytochrome b5 reductase activity|NADH-cytochrome-b5 reductase activity|NADH:ferricytochrome-b5 oxidoreductase activity|NADH-ferricytochrome b5 oxidoreductase activity											Reactome:R-HSA-6806831|Reactome:R-HSA-198824|RHEA:46680|MetaCyc:CYTOCHROME-B5-REDUCTASE-RXN|EC:1.6.2.2		molecular_function											owl:Class	
GO:0090619	biolink:NamedThing	meiotic spindle pole	Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	got7fsn_ti							tb	2014-12-16T16:38:34Z						cellular_component											owl:Class	
GO:0000922	biolink:NamedThing	spindle pole	Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	got7fsn_ti											GO:0030615			cellular_component											owl:Class	
GO:0048794	biolink:NamedThing	swim bladder development	The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	got7fsn_ti	gas bladder development													biological_process											owl:Class	
GO:0019652	biolink:NamedThing	lactate fermentation to propionate and acetate	The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP).	got7fsn_ti	nonrandomizing pathway|propionate fermentation|acrylate pathway											MetaCyc:PROPFERM-PWY		biological_process											owl:Class	
GO:0019662	biolink:NamedThing	non-glycolytic fermentation	Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.	got7fsn_ti														biological_process											owl:Class	
GO:0043333	biolink:NamedThing	2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity	Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	got7fsn_ti	2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	https://github.com/geneontology/go-ontology/issues/15686			Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.						GO:0102005	MetaCyc:2-OCTAPRENYL-METHOXY-BENZOQ-METH-RXN|EC:2.1.1.201		molecular_function											owl:Class	
GO:0102499	biolink:NamedThing	SHG alpha-glucan phosphorylase activity	Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan.	got7fsn_ti												EC:2.4.1.1|MetaCyc:RXN-14353|RHEA:41732		molecular_function											owl:Class	
GO:0102057	biolink:NamedThing	jasmonoyl-valine synthetase activity	Catalysis of the reaction: L-valine  + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine.	got7fsn_ti												MetaCyc:RXN-10457		molecular_function											owl:Class	
GO:0061272	biolink:NamedThing	mesonephric connecting tubule development	The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.	got7fsn_ti	mesonephric connecting duct development|mesonephric collecting tubule development						dph	2010-09-02T12:00:56Z						biological_process											owl:Class	
GO:0061242	biolink:NamedThing	mesonephric nephron tubule development	The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.	got7fsn_ti							dph	2010-08-19T03:17:00Z						biological_process											owl:Class	
GO:0004386	biolink:NamedThing	helicase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.	got7fsn_ti	ATP-dependent helicase activity	https://github.com/geneontology/go-ontology/issues/21393			Note that most helicases catalyze processive duplex unwinding.						GO:0008026	Reactome:R-HSA-169461|Reactome:R-HSA-5686410|Reactome:R-HSA-169468|Reactome:R-HSA-5690996		molecular_function											owl:Class	
GO:0030666	biolink:NamedThing	endocytic vesicle membrane	The lipid bilayer surrounding an endocytic vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0097579	biolink:NamedThing	extracellular sequestering of copper ion	The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system.	got7fsn_ti	extracellular copper ion sequestering|extracellular sequestration of copper ion|extracellular retention of copper ion|extracellular storage of copper ion|extracellular copper ion retention|extracellular copper ion storage|extracellular copper ion sequestration						pr	2014-02-28T11:18:04Z						biological_process											owl:Class	
GO:0008123	biolink:NamedThing	cholesterol 7-alpha-monooxygenase activity	Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O.	got7fsn_ti	cholesterol 7alpha-monooxygenase activity|cholesterol 7alpha-hydroxylase activity|cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)|cholesterol 7-alpha-hydroxylase activity|cytochrome P450 CYP7A1											Reactome:R-HSA-192051|MetaCyc:CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN|RHEA:21812|EC:1.14.14.23		molecular_function											owl:Class	
GO:0021904	biolink:NamedThing	dorsal/ventral neural tube patterning	The process in which the neural tube is regionalized in the dorsoventral axis.	got7fsn_ti	dorsal-ventral neural tube patterning|dorsoventral neural tube patterning													biological_process											owl:Class	
GO:1900592	biolink:NamedThing	violaceol II catabolic process	The chemical reactions and pathways resulting in the breakdown of violaceol II.	got7fsn_ti	violaceol II degradation|violaceol II breakdown|violaceol II catabolism						di	2012-05-15T06:51:43Z						biological_process											owl:Class	
GO:0038186	biolink:NamedThing	lithocholic acid receptor activity	Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity.	got7fsn_ti	LCA receptor activity						bf	2013-05-16T11:13:38Z						molecular_function											owl:Class	
GO:0038181	biolink:NamedThing	bile acid receptor activity	Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile.	got7fsn_ti							bf	2013-05-16T10:27:02Z						molecular_function											owl:Class	
GO:0102980	biolink:NamedThing	2-butyl-4-hydroxy-5-methyl-3(2H)-furanoneoxidoreductase activity	Catalysis of the reaction: 2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP <=> (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-9565		molecular_function											owl:Class	
GO:0090441	biolink:NamedThing	trehalose biosynthesis in response to heat stress	The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	got7fsn_ti	trehalose biosynthetic process in response to heat stress						tb	2012-08-23T13:53:07Z						biological_process											owl:Class	
GO:0009092	biolink:NamedThing	homoserine metabolic process	The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.	got7fsn_ti	homoserine metabolism													biological_process											owl:Class	
GO:0061318	biolink:NamedThing	renal filtration cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	got7fsn_ti							dph	2010-09-24T12:18:35Z						biological_process											owl:Class	
GO:0050891	biolink:NamedThing	multicellular organismal water homeostasis	Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.	got7fsn_ti	body fluid osmoregulation													biological_process											owl:Class	
GO:0018642	biolink:NamedThing	chlorophenol 4-monooxygenase activity	Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol.	got7fsn_ti												UM-BBD_enzymeID:e0252|EC:1.14.13.-		molecular_function											owl:Class	
GO:0048016	biolink:NamedThing	inositol phosphate-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6).	got7fsn_ti	inositol phosphate-mediated signalling													biological_process											owl:Class	
GO:0019932	biolink:NamedThing	second-messenger-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell.	got7fsn_ti	second messenger-mediated signalling|second-messenger-mediated signal transduction|second messenger-mediated signaling|second-messenger-mediated signalling|second messenger mediated signaling|second messenger mediated signalling													biological_process											owl:Class	
GO:0101020	biolink:NamedThing	estrogen 16-alpha-hydroxylase activity	Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.	got7fsn_ti	oestrogen 16-alpha-hydroxylase activity													molecular_function											owl:Class	
GO:0030026	biolink:NamedThing	cellular manganese ion homeostasis	Any process involved in the maintenance of an internal steady state of manganese ions at the level of a cell.	got7fsn_ti	manganese homeostasis													biological_process											owl:Class	
GO:0055071	biolink:NamedThing	manganese ion homeostasis	Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell.	got7fsn_ti	manganese homeostasis													biological_process											owl:Class	
GO:0031809	biolink:NamedThing	H3 histamine receptor binding	Binding to a H3 histamine receptor.	got7fsn_ti	H3 histamine receptor ligand													molecular_function											owl:Class	
GO:0050941	biolink:NamedThing	negative regulation of pigment cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.	got7fsn_ti	downregulation of pigment cell differentiation|inhibition of pigment cell differentiation|down-regulation of pigment cell differentiation|down regulation of pigment cell differentiation													biological_process											owl:Class	
GO:0048086	biolink:NamedThing	negative regulation of developmental pigmentation	Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.	got7fsn_ti	downregulation of developmental pigmentation|down regulation of developmental pigmentation|inhibition of pigmentation|down-regulation of developmental pigmentation													biological_process											owl:Class	
GO:0072289	biolink:NamedThing	metanephric nephron tubule formation	The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.	got7fsn_ti							mah	2010-04-09T03:47:44Z						biological_process											owl:Class	
GO:0072079	biolink:NamedThing	nephron tubule formation	The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.	got7fsn_ti							mah	2010-02-01T02:29:26Z						biological_process											owl:Class	
GO:0120122	biolink:NamedThing	prolactin metabolic process	The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals.	got7fsn_ti	prolactin metabolism						krc	2018-01-25T17:28:40Z						biological_process											owl:Class	
GO:2001003	biolink:NamedThing	regulation of pectin catabolic process	Any process that modulates the frequency, rate or extent of pectin catabolic process.	got7fsn_ti	regulation of pectin breakdown|regulation of pectin catabolism|regulation of pectin degradation						tt	2011-08-08T03:24:01Z						biological_process											owl:Class	
GO:0021606	biolink:NamedThing	accessory nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	got7fsn_ti	spinal accessory nerve maturation|CN XI maturation													biological_process											owl:Class	
GO:0098517	biolink:NamedThing	detection of low humidity	The series of events in which low humidity is detected and converted into a molecular signal.	got7fsn_ti							dos	2013-09-25T14:27:18Z						biological_process											owl:Class	
GO:0098513	biolink:NamedThing	detection of humidity	The series of events in which a humidity stimulus is received and converted into a molecular signal.	got7fsn_ti							dos	2013-09-25T14:11:13Z						biological_process											owl:Class	
GO:0046730	biolink:NamedThing	induction by virus of host immune response	The induction by a virus of an immune response in the host organism.	got7fsn_ti	passive induction of humoral immune response in host by virus|passive viral activation of humoral immune response in host|passive induction of host innate immune response by virus|passive induction of cell-mediated immune response in host by virus|passive viral activation of innate immune response in host|passive viral induction of host immune response|passive induction of host cell-mediated immune response by virus|passive viral induction of cell-mediated immune response in host|active viral induction of host immune response|passive viral induction of innate immune response in host|passive viral induction of humoral immune response in host|passive viral activation of cell-mediated immune response in host|passive induction of innate immune response in host by virus|passive induction of host immune response by virus|active induction of host immune response by virus|activation of host immune response by virus|passive induction of host humoral immune response by virus|passive activation of host immune response by virus										GO:0046735|GO:0046734|GO:0046733|GO:0046731|GO:0046732			biological_process											owl:Class	
GO:0004798	biolink:NamedThing	thymidylate kinase activity	Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.	got7fsn_ti	ATP:dTMP phosphotransferase activity|deoxythymidine 5'-monophosphate kinase activity|thymidylate monophosphate kinase activity|thymidine monophosphate kinase activity|thymidylic acid kinase activity|TMPK activity|thymidine 5'-monophosphate kinase activity|thymidylic kinase activity|dTMP kinase activity											EC:2.7.4.9|MetaCyc:DTMPKI-RXN|RHEA:13517		molecular_function											owl:Class	
GO:0016464	biolink:NamedThing	chloroplast protein-transporting ATPase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.	got7fsn_ti	ATPase-coupled chloroplast protein transporter activity|AAA chloroplast protein-transporting ATPase											MetaCyc:3.6.3.52-RXN|EC:7.4.2.4		molecular_function											owl:Class	
GO:0015450	biolink:NamedThing	protein-transporting ATPase activity	Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.	got7fsn_ti	P-P-bond-hydrolysis-driven protein transmembrane transporter activity|protein translocase activity	https://github.com/geneontology/go-ontology/issues/21271										Reactome:R-HSA-1222523		molecular_function											owl:Class	
GO:0046805	biolink:NamedThing	protein-heme linkage via 1'-L-histidine	The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine).	got7fsn_ti	protein-haem linkage via 1'-L-histidine											RESID:AA0329		biological_process											owl:Class	
GO:0023056	biolink:NamedThing	positive regulation of signaling	Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.	got7fsn_ti	positive regulation of signalling process|positive regulation of signaling process							2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0097571	biolink:NamedThing	left nucleus	One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side.	got7fsn_ti					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-18T11:21:31Z						cellular_component											owl:Class	
GO:0030565	biolink:NamedThing	snRNA pseudouridylation guide activity	Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. Note that this term may be useful for annotating snoRNAs.									molecular_function											owl:Class	
GO:0097115	biolink:NamedThing	neurexin clustering involved in presynaptic membrane assembly	The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.	got7fsn_ti	neurexin clustering|Nrxn clustering|presynaptic neurexin clustering						pr	2011-07-31T05:40:00Z						biological_process											owl:Class	
GO:0018358	biolink:NamedThing	protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine	The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine.	got7fsn_ti											GO:0018381	RESID:AA0133		biological_process											owl:Class	
GO:0017012	biolink:NamedThing	protein-phytochromobilin linkage	The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin.	got7fsn_ti												RESID:AA0133		biological_process											owl:Class	
GO:0050422	biolink:NamedThing	strictosidine beta-glucosidase activity	Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = D-glucose + strictosidine aglycone.	got7fsn_ti	strictosidine b-glucosidase activity|strictosidine beta-D-glucohydrolase activity											KEGG_REACTION:R03820|MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN|RHEA:12917|EC:3.2.1.105		molecular_function											owl:Class	
GO:0070583	biolink:NamedThing	spore membrane bending pathway	The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.	got7fsn_ti	forespore membrane bending|FSM bending|ascospore-type prospore membrane bending						mah	2009-04-24T10:48:09Z						biological_process											owl:Class	
GO:0072721	biolink:NamedThing	cellular response to dithiothreitol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.	got7fsn_ti	cellular response to DTT|cellular response to 1,4-dithiothreitol						mah	2012-05-09T11:09:08Z						biological_process											owl:Class	
GO:0071734	biolink:NamedThing	biotin-[pyruvate-carboxylase] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase).	got7fsn_ti	biotin:apo-pyruvate-carboxylase ligase|biotin-[pyruvate carboxylase] ligase activity|biotin-[pyruvate carboxylase] synthetase activity|biotin-pyruvate-carboxylase ligase activity|biotin-pyruvate carboxylase synthetase activity						mah	2010-03-19T02:37:24Z				EC:6.3.4.-		molecular_function											owl:Class	
GO:0042081	biolink:NamedThing	GSI anchor metabolic process	The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane.	got7fsn_ti	GPI/GSI anchor metabolism|GSI anchor metabolism|GPI/GSI anchor metabolic process													biological_process											owl:Class	
GO:0006687	biolink:NamedThing	glycosphingolipid metabolic process	The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.	got7fsn_ti	glycosphingolipid metabolism													biological_process											owl:Class	
GO:0089700	biolink:NamedThing	protein kinase D signaling	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase D, which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	PKD signaling cascade|protein kinase D signalling cascade|protein kinase D signal transduction|PKD signal transduction|protein kinase D signaling cascade													biological_process											owl:Class	
GO:0031236	biolink:NamedThing	extrinsic component of periplasmic side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to external side of plasma membrane, in periplasmic space|extrinsic to external leaflet of plasma membrane, in periplasmic space										GO:0031238			cellular_component											owl:Class	
GO:0097097	biolink:NamedThing	nasal suture morphogenesis	The process in which the nasal suture is generated and organized.	got7fsn_ti	internasal suture morphogenesis						pr	2011-07-05T03:09:04Z						biological_process											owl:Class	
GO:0097096	biolink:NamedThing	facial suture morphogenesis	The process in which any suture between facial bones is generated and organized.	got7fsn_ti							pr	2011-07-05T03:06:27Z						biological_process											owl:Class	
GO:0099053	biolink:NamedThing	activating signal cointegrator 1 complex	A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.  In humans this complex has 4 subunits: TRIP4 + ASCC1-3.	got7fsn_ti	ASC-1 complex													cellular_component											owl:Class	
GO:0035962	biolink:NamedThing	response to interleukin-13	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.	got7fsn_ti	response to IL-13						bf	2011-08-01T11:29:02Z						biological_process											owl:Class	
GO:0042365	biolink:NamedThing	water-soluble vitamin catabolic process	The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water.	got7fsn_ti	water-soluble vitamin breakdown|water-soluble vitamin catabolism|water-soluble vitamin degradation													biological_process											owl:Class	
GO:0007301	biolink:NamedThing	female germline ring canal formation	Assembly of the intercellular bridges that connect the germ-line cells of a female cyst.	got7fsn_ti	nurse cell ring canal formation|ovarian ring canal formation													biological_process											owl:Class	
GO:0030725	biolink:NamedThing	germline ring canal formation	Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts.	got7fsn_ti	ring canal formation													biological_process											owl:Class	
GO:0034055	biolink:NamedThing	effector-mediated induction of programmed cell death in host	A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	upregulation by symbiont of host defense-related programmed cell death|up regulation by symbiont of host defense-related programmed cell death|enhancement by symbiont of host defense-related programmed cell death|activation by symbiont of host defense-related programmed cell death|stimulation by symbiont of host defense-related programmed cell death|positive regulation by symbiont of host defense-related programmed cell death|up-regulation by symbiont of host defense-related programmed cell death|positive regulation by symbiont of host defense-related PCD	https://github.com/geneontology/go-ontology/issues/20284			Note that this term is used to annotate gene products of the symbiont.									biological_process											owl:Class	
GO:0034053	biolink:NamedThing	modulation by symbiont of host defense-related programmed cell death	Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host hypersensitive response|modulation by symbiont of host HR|modulation by symbiont of host defense-related PCD|modulation by symbiont of plant HR|modulation by symbiont of plant hypersensitive response				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'plant-type hypersensitive response ; GO:0009626'.									biological_process											owl:Class	
GO:0021839	biolink:NamedThing	interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex	The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0023026	biolink:NamedThing	MHC class II protein complex binding	Binding to a class II major histocompatibility complex.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0033847	biolink:NamedThing	O-phosphoserine sulfhydrylase activity	Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate.	got7fsn_ti	O-phosphoserine(thiol)-lyase activity|O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity											RHEA:10252|EC:2.5.1.65|MetaCyc:2.5.1.65-RXN		molecular_function											owl:Class	
GO:0032571	biolink:NamedThing	response to vitamin K	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0090442	biolink:NamedThing	trehalose catabolism in response to heat stress	The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	got7fsn_ti	trehalose catabolic process in response to heat stress						tb	2012-08-23T13:53:07Z						biological_process											owl:Class	
GO:0010786	biolink:NamedThing	clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.	got7fsn_ti														biological_process											owl:Class	
GO:0048202	biolink:NamedThing	clathrin coating of Golgi vesicle	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.	got7fsn_ti	clathrin coating of Golgi-derived vesicle													biological_process											owl:Class	
GO:0042815	biolink:NamedThing	bipolar cell growth	The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell.	got7fsn_ti	bipolar growth|polar cell elongation|bipolar cell elongation				Bipolar cell growth refers to a change in both cell size and cell shape. For shape changes where cell size is not affected, consider instead the term 'establishment or maintenance of bipolar cell polarity resulting in cell shape ; GO:0061246' and its children.									biological_process											owl:Class	
GO:0102687	biolink:NamedThing	UDP-glucose:dihydrozeatin 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + dihydrozeatin-7-N-glucose + UDP.	got7fsn_ti												MetaCyc:RXN-4724		molecular_function											owl:Class	
GO:0004826	biolink:NamedThing	phenylalanine-tRNA ligase activity	Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).	got7fsn_ti	L-phenylalanyl-tRNA synthetase activity|phenylalanyl-tRNA synthetase activity|phenylalanyl-transfer RNA ligase activity|phenylalanyl-tRNA ligase activity|phenylalanine translase activity|phenylalanyl-transfer ribonucleate synthetase activity|L-phenylalanine:tRNAPhe ligase (AMP-forming) activity|phenylalanine-tRNA synthetase activity|phenylalanyl-transfer RNA synthetase activity											RHEA:19413|EC:6.1.1.20|MetaCyc:PHENYLALANINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380203|Reactome:R-HSA-379848		molecular_function											owl:Class	
GO:0102487	biolink:NamedThing	dUTP phosphohydrolase activity	Catalysis of the reaction: dUTP + 2 H2O = dUMP + 2 hydrogenphosphate + 2 H+.	got7fsn_ti												MetaCyc:RXN-14199|EC:3.6.1.5		molecular_function											owl:Class	
GO:0008048	biolink:NamedThing	calcium sensitive guanylate cyclase activator activity	Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.	got7fsn_ti														molecular_function											owl:Class	
GO:0030250	biolink:NamedThing	guanylate cyclase activator activity	Binds to and increases the activity of guanylate cyclase.	got7fsn_ti	guanylin													molecular_function											owl:Class	
GO:0047832	biolink:NamedThing	D-pinitol dehydrogenase activity	Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH.	got7fsn_ti	1D-3-O-methyl-chiro-inositol:NADP+ oxidoreductase activity|5D-5-O-methyl-chiro-inositol:NADP+ oxidoreductase activity											KEGG_REACTION:R03498|RHEA:20437|EC:1.1.1.142|MetaCyc:D-PINITOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0008773	biolink:NamedThing	[protein-PII] uridylyltransferase activity	Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).	got7fsn_ti	UTP:[protein-PII] uridylyltransferase activity|UTP:protein-PII uridylyltransferase activity|uridylyl removing enzyme activity|PII uridylyl-transferase activity|protein-PII uridylyltransferase activity|uridyl removing enzyme											EC:2.7.7.59|RHEA:13673|MetaCyc:URITRANS-RXN		molecular_function											owl:Class	
GO:0018102	biolink:NamedThing	peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine	The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine.	got7fsn_ti												RESID:AA0215		biological_process											owl:Class	
GO:0030543	biolink:NamedThing	2-micrometer plasmid partitioning	The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0030541	biolink:NamedThing	plasmid partitioning	Any process in which plasmids are segregated or distributed into daughter cells upon cell division.	got7fsn_ti											GO:0030542			biological_process											owl:Class	
GO:0018107	biolink:NamedThing	peptidyl-threonine phosphorylation	The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	got7fsn_ti												RESID:AA0038		biological_process											owl:Class	
GO:0035766	biolink:NamedThing	cell chemotaxis to fibroblast growth factor	The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF).	got7fsn_ti							bf	2011-03-31T04:30:16Z						biological_process											owl:Class	
GO:0019340	biolink:NamedThing	dibenzofuran catabolic process	The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond.	got7fsn_ti	dibenzofuran catabolism|dibenzofuran breakdown|dibenzofuran degradation											MetaCyc:P662-PWY		biological_process											owl:Class	
GO:0061852	biolink:NamedThing	retrograte transporter complex, Golgi to ER	Transporter complex that recognises, binds and returns endoplasmic reticulum (ER) resident proteins that have trafficked to Golgi compartments. Targets proteins lacking the HDEL motif recognised by COPI-coated vesicles.	got7fsn_ti	ERV41-ERV46 retrograde receptor complex|retrograte receptor complex, Golgi to endoplasmic reticulum|retrograte transporter complex, Golgi to endoplasmic reticulum|retrograte receptor complex, Golgi to ER				An example of this is ERV41 in Saccharomyces cerevisiae (Q04651) in PMID:16093310 (inferred from direct assay).		dph	2017-02-28T13:56:56Z						cellular_component											owl:Class	
GO:0102524	biolink:NamedThing	tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity	Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe.	got7fsn_ti												MetaCyc:RXN-14538|RHEA:37899|EC:1.14.11.42		molecular_function											owl:Class	
GO:0036476	biolink:NamedThing	neuron death in response to hydrogen peroxide	Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to hydrogen peroxide (H2O2).	got7fsn_ti	neuronal cell death in response to hydrogen peroxide|neuron death in response to H2O2|hydrogen peroxide-induced neuron death				This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0010421 'hydrogen peroxide-mediated programmed cell death'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate.		bf	2014-07-21T11:46:31Z						biological_process											owl:Class	
GO:0036475	biolink:NamedThing	neuron death in response to oxidative stress	Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to an oxidative stress stimulus.	got7fsn_ti	oxidative stress-induced neuron death|neuronal cell death in response to oxidative stress				This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0010421 'hydrogen peroxide-mediated programmed cell death'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate.		bf	2014-07-21T11:44:40Z						biological_process											owl:Class	
GO:0070490	biolink:NamedThing	protein pupylation	The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.	got7fsn_ti	Pup-protein conjugation|pupylation													biological_process											owl:Class	
GO:0097145	biolink:NamedThing	BAK complex	An oligomeric protein complex consisting of BAK, a member of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:48:11Z						cellular_component											owl:Class	
GO:0106273	biolink:NamedThing	cytosol to ERGIC protein transport	The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).	got7fsn_ti							hjd	2020-07-01T17:28:07Z						biological_process											owl:Class	
GO:0038171	biolink:NamedThing	cannabinoid signaling pathway	The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.	got7fsn_ti	cannabinoid-mediated signaling pathway|cannabinoid-activated signaling pathway|cannabinoid receptor signaling pathway						bf	2012-06-12T10:47:53Z						biological_process											owl:Class	
GO:0003712	biolink:NamedThing	transcription coregulator activity	A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.	got7fsn_ti	transcription cofactor activity|transcriptional co-regulator|RNA polymerase II transcriptional cofactor activity	https://github.com/geneontology/go-ontology/issues/15665|https://github.com/geneontology/go-ontology/issues/15998|https://github.com/geneontology/go-ontology/issues/15536|https://github.com/geneontology/go-ontology/issues/20862|https://github.com/geneontology/go-ontology/issues/20464|https://github.com/geneontology/go-ontology/issues/20962|https://github.com/geneontology/go-ontology/issues/20253			Usage guidance: Most transcription coregulators do not bind DNA. Those that do usually bind DNA either in a non-specific or non-direct manner. If a protein binds DNA specifically, consider annotating to GO:0003700 DNA binding transcription factor activity.		krc	2010-11-24T03:02:15Z			GO:0001104|GO:0016455			molecular_function											owl:Class	
GO:0009244	biolink:NamedThing	lipopolysaccharide core region biosynthetic process	The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues.	got7fsn_ti	lipopolysaccharide core region biosynthesis|LPS core region biosynthetic process|lipopolysaccharide core region anabolism|lipopolysaccharide core region formation|lipopolysaccharide core region synthesis													biological_process											owl:Class	
GO:0046401	biolink:NamedThing	lipopolysaccharide core region metabolic process	The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains.	got7fsn_ti	LPS core region metabolic process|lipopolysaccharide core region metabolism													biological_process											owl:Class	
GO:0071339	biolink:NamedThing	MLL1 complex	A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.	got7fsn_ti							mah	2009-12-11T11:11:36Z						cellular_component											owl:Class	
GO:0044665	biolink:NamedThing	MLL1/2 complex	A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species.	got7fsn_ti	Trx-containing complex						jl	2012-08-07T14:44:12Z						cellular_component											owl:Class	
GO:0097528	biolink:NamedThing	execution phase of necroptosis	A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died.	got7fsn_ti	necroptotic execution phase|execution phase of necroptotic process|necroptosis						pr	2013-11-05T14:23:53Z						biological_process											owl:Class	
GO:0021877	biolink:NamedThing	forebrain neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0018189	biolink:NamedThing	pyrroloquinoline quinone biosynthetic process	The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.	got7fsn_ti	coenzyme pyrroloquinoline-quinone biosynthesis|pyrroloquinoline quinone biosynthesis|pyrroloquinoline quinone anabolism|pyrroloquinoline quinone formation|PQQ biosynthetic process|PQQ biosynthesis|pyrroloquinoline-quinone biosynthesis|coenzyme pyrroloquinoline-quinone biosynthetic process|pyrroloquinoline quinone synthesis|pyrroloquinoline-quinone biosynthetic process	https://github.com/geneontology/go-ontology/issues/20547										RESID:AA0283		biological_process											owl:Class	
GO:0002772	biolink:NamedThing	inhibitory C-type lectin receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.	got7fsn_ti	Ly49 inhibitory receptor signaling pathway|inhibitory C-type lectin receptor signalling pathway													biological_process											owl:Class	
GO:0032836	biolink:NamedThing	glomerular basement membrane development	The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.	got7fsn_ti														biological_process											owl:Class	
GO:0098627	biolink:NamedThing	protein arginine phosphatase activity	Catalysis of the reaction: protein arginine phosphate + H2O = protein arginine + phosphate.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21517			Made part of peptidyl-N-phospho-arginine phosphatase activity on the assumption that arginine phosphorylation in proteins occurs via an N link.		dos	2014-04-17T17:57:39Z				EC:3.9.1.2|RHEA:43380		molecular_function											owl:Class	
GO:0016825	biolink:NamedThing	hydrolase activity, acting on acid phosphorus-nitrogen bonds	Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond.	got7fsn_ti												EC:3.9.1.-		molecular_function											owl:Class	
GO:0047833	biolink:NamedThing	D-sorbitol dehydrogenase (acceptor) activity	Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor.	got7fsn_ti	D-sorbitol:acceptor 1-oxidoreductase activity|D-sorbitol dehydrogenase activity|D-sorbitol:(acceptor) 1-oxidoreductase activity											RHEA:21320|MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN|EC:1.1.99.21		molecular_function											owl:Class	
GO:0034901	biolink:NamedThing	endosulfan hydroxyether dehydrogenase activity	Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1411		molecular_function											owl:Class	
GO:0070591	biolink:NamedThing	ascospore wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.	got7fsn_ti							mah	2009-04-28T01:12:11Z						biological_process											owl:Class	
GO:0009272	biolink:NamedThing	fungal-type cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin.	got7fsn_ti	fungal-type cell wall anabolism|fungal-type cell wall biosynthetic process|fungal-type cell wall synthesis|fungal-type cell wall formation|chitin- and beta-glucan-containing cell wall biogenesis													biological_process											owl:Class	
GO:0007305	biolink:NamedThing	vitelline membrane formation involved in chorion-containing eggshell formation	Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.	got7fsn_ti	vitelline membrane formation in chorion-containing eggshell													biological_process											owl:Class	
GO:0030704	biolink:NamedThing	vitelline membrane formation	Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.	got7fsn_ti														biological_process											owl:Class	
GO:0016223	biolink:NamedThing	beta-alanine-pyruvate transaminase activity	Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.	got7fsn_ti	beta-alanine--pyruvate aminotransferase activity|L-alanine:3-oxopropanoate aminotransferase activity|omega-amino acid--pyruvate aminotransferase activity|beta-alanine-pyruvate aminotransferase activity|beta-alanine-alpha-alanine transaminase activity											EC:2.6.1.18|RHEA:14077|MetaCyc:2.6.1.18-RXN|Reactome:R-HSA-909776		molecular_function											owl:Class	
GO:0036278	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen.	got7fsn_ti							bf	2012-07-11T11:02:55Z						biological_process											owl:Class	
GO:0060537	biolink:NamedThing	muscle tissue development	The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.	got7fsn_ti							dph	2009-04-10T08:05:37Z						biological_process											owl:Class	
GO:0047935	biolink:NamedThing	glucose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH.	got7fsn_ti	nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase activity|D-glucose:NADP+ 1-oxidoreductase activity|NADP-linked aldohexose dehydrogenase activity|NADP-dependent glucose dehydrogenase activity											MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.119|RHEA:14405		molecular_function											owl:Class	
GO:0047936	biolink:NamedThing	glucose 1-dehydrogenase [NAD(P)] activity	Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H.	got7fsn_ti	beta-D-glucose:NAD(P)+ 1-oxidoreductase activity|D-glucose dehydrogenase (NAD(P))|hexose phosphate dehydrogenase activity											MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.47		molecular_function											owl:Class	
GO:0060714	biolink:NamedThing	labyrinthine layer formation	The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.	got7fsn_ti							dph	2009-06-10T08:13:14Z						biological_process											owl:Class	
GO:0008816	biolink:NamedThing	citryl-CoA lyase activity	Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.	got7fsn_ti	(3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)|(3S)-citryl-CoA oxaloacetate-lyase activity											RHEA:20812|MetaCyc:CITRYLY-RXN|EC:4.1.3.34		molecular_function											owl:Class	
GO:0061536	biolink:NamedThing	glycine secretion	The controlled release of glycine by a cell.	got7fsn_ti							dph	2013-06-21T16:18:23Z						biological_process											owl:Class	
GO:0032940	biolink:NamedThing	secretion by cell	The controlled release of a substance by a cell.	got7fsn_ti	cellular secretion											Wikipedia:Secretion		biological_process											owl:Class	
GO:0097598	biolink:NamedThing	sperm cytoplasmic droplet	A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from 'excessive residual cytoplasm' that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted.	got7fsn_ti	sperm residual cytoplasm						pr	2014-04-10T14:03:30Z						cellular_component											owl:Class	
GO:0048798	biolink:NamedThing	swim bladder inflation	The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	got7fsn_ti	gas bladder inflation													biological_process											owl:Class	
GO:0047714	biolink:NamedThing	galactolipase activity	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates.	got7fsn_ti	galactolipid lipase activity|polygalactolipase activity|galactolipid acylhydrolase activity|1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase activity											EC:3.1.1.26|RHEA:13189|MetaCyc:GALACTOLIPASE-RXN		molecular_function											owl:Class	
GO:0103003	biolink:NamedThing	oleate peroxygenase activity	Catalysis of the reaction: oleate + a lipid hydroperoxide <=> 9,10-epoxystearate + a lipid alcohol.	got7fsn_ti												MetaCyc:RXN-9804		molecular_function											owl:Class	
GO:0016684	biolink:NamedThing	oxidoreductase activity, acting on peroxide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.	got7fsn_ti												EC:1.11.-.-		molecular_function											owl:Class	
GO:0070398	biolink:NamedThing	wall teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.	got7fsn_ti	wall teichoic acid anabolism|wall teichoic acid synthesis|wall teichoic acid formation|WTA biosynthetic process|wall teichoic acid biosynthesis													biological_process											owl:Class	
GO:0004054	biolink:NamedThing	arginine kinase activity	Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H(+).	got7fsn_ti	ATP:L-arginine N-phosphotransferase activity|adenosine 5'-triphosphate:L-arginine|adenosine 5'-triphosphate-arginine phosphotransferase activity|arginine phosphokinase activity											KEGG_REACTION:R00554|RHEA:22940|EC:2.7.3.3|MetaCyc:ARGININE-KINASE-RXN		molecular_function											owl:Class	
GO:0019202	biolink:NamedThing	amino acid kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate.	got7fsn_ti														molecular_function											owl:Class	
GO:0036492	biolink:NamedThing	eiF2alpha phosphorylation in response to endoplasmic reticulum stress	The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.	got7fsn_ti	regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|eiF2alpha phosphorylation in response to ER stress						bf	2015-02-05T09:53:21Z						biological_process											owl:Class	
GO:0036491	biolink:NamedThing	regulation of translation initiation in response to endoplasmic reticulum stress	Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress.	got7fsn_ti	regulation of translation initiation in response to ER stress						bf	2015-02-05T09:52:13Z						biological_process											owl:Class	
GO:0071805	biolink:NamedThing	potassium ion transmembrane transport	A process in which a potassium ion is transported from one side of a membrane to the other.	got7fsn_ti	high-affinity potassium ion import|high-affinity potassium ion uptake|high affinity potassium ion uptake|high affinity potassium ion import|potassium ion membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-09-03T02:43:49Z			GO:0010163			biological_process											owl:Class	
GO:0034424	biolink:NamedThing	Vps55/Vps68 complex	A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0035167	biolink:NamedThing	larval lymph gland hemopoiesis	The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.	got7fsn_ti	larval lymph gland haematopoiesis|larval lymph gland hematopoiesis|larval lymph gland haemopoiesis													biological_process											owl:Class	
GO:0035166	biolink:NamedThing	post-embryonic hemopoiesis	The stages of blood cell formation that take place after completion of embryonic development.	got7fsn_ti	post-embryonic haemopoiesis													biological_process											owl:Class	
GO:0120160	biolink:NamedThing	intraciliary transport particle A binding	Binding to an intraciliary transport particle A (IFT A) complex.	got7fsn_ti	intraflagellar transport particle A binding|intraflagellar transport complex A binding|intraciliary transport complex A binding|IFT A complex binding						krc	2018-05-11T22:28:11Z						molecular_function											owl:Class	
GO:0070212	biolink:NamedThing	protein poly-ADP-ribosylation	The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.	got7fsn_ti	addition of poly-ADP-ribose to protein|protein amino acid poly-ADP-ribosylation|poly(ADP-ribose) addition to protein|protein poly(ADP-ribose) synthesis|protein poly(ADP-ribose) metabolism													biological_process											owl:Class	
GO:0002086	biolink:NamedThing	diaphragm contraction	A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange.	got7fsn_ti														biological_process											owl:Class	
GO:0003016	biolink:NamedThing	respiratory system process	A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.	got7fsn_ti	respiratory gaseous exchange										GO:0010802			biological_process											owl:Class	
GO:0044036	biolink:NamedThing	cell wall macromolecule metabolic process	The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	got7fsn_ti	cellular cell wall macromolecule metabolism|cellular cell wall macromolecule metabolic process										GO:0010382			biological_process											owl:Class	
GO:0045815	biolink:NamedThing	positive regulation of gene expression, epigenetic	Any epigenetic process that activates or increases the rate of gene expression.	got7fsn_ti	stimulation of gene expression, epigenetic|up regulation of gene expression, epigenetic|up-regulation of gene expression, epigenetic|upregulation of gene expression, epigenetic|activation of gene expression, epigenetic|long-term maintenance of gene activation													biological_process											owl:Class	
GO:0019883	biolink:NamedThing	antigen processing and presentation of endogenous antigen	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.	got7fsn_ti	antigen presentation, endogenous antigen													biological_process											owl:Class	
GO:0043562	biolink:NamedThing	cellular response to nitrogen levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen.	got7fsn_ti														biological_process											owl:Class	
GO:0001692	biolink:NamedThing	histamine metabolic process	The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	got7fsn_ti	histamine metabolism													biological_process											owl:Class	
GO:0052803	biolink:NamedThing	imidazole-containing compound metabolic process	The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.	got7fsn_ti	imidazole metabolism													biological_process											owl:Class	
GO:1990983	biolink:NamedThing	tRNA demethylation	The removal of a methyl group from one or more residues within a tRNA molecule.	got7fsn_ti							sp	2016-10-28T08:32:59Z						biological_process											owl:Class	
GO:0009503	biolink:NamedThing	thylakoid light-harvesting complex	A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana.	got7fsn_ti														cellular_component											owl:Class	
GO:0051638	biolink:NamedThing	barbed-end actin filament uncapping	The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.	got7fsn_ti	plus end actin filament uncapping|plus end F-actin uncapping|barbed end F-actin uncapping|barbed end actin filament uncapping|plus-end F-actin uncapping|plus-end actin filament uncapping|barbed-end F-actin uncapping													biological_process											owl:Class	
GO:0051695	biolink:NamedThing	actin filament uncapping	The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.	got7fsn_ti	F-actin uncapping													biological_process											owl:Class	
GO:0031175	biolink:NamedThing	neuron projection development	The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	got7fsn_ti	neurite outgrowth|neurite growth|neurite development|neurite biosynthesis|neurite formation													biological_process											owl:Class	
GO:0071380	biolink:NamedThing	cellular response to prostaglandin E stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.	got7fsn_ti							mah	2009-12-11T03:34:43Z						biological_process											owl:Class	
GO:0034695	biolink:NamedThing	response to prostaglandin E	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.	got7fsn_ti	response to prostaglandin E stimulus													biological_process											owl:Class	
GO:0072053	biolink:NamedThing	renal inner medulla development	The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.	got7fsn_ti	inner renal medulla development						mah	2010-01-25T03:59:37Z						biological_process											owl:Class	
GO:0018591	biolink:NamedThing	methyl tertiary butyl ether 3-monooxygenase activity	Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde.	got7fsn_ti	MTBE 3-monooxygenase activity													molecular_function											owl:Class	
GO:0030322	biolink:NamedThing	stabilization of membrane potential	The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0070665	biolink:NamedThing	positive regulation of leukocyte proliferation	Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.	got7fsn_ti	upregulation of leukocyte proliferation|up regulation of leukocyte proliferation|up-regulation of leukocyte proliferation|stimulation of leukocyte proliferation|activation of leukocyte proliferation						mah	2009-05-28T05:36:46Z						biological_process											owl:Class	
GO:0008284	biolink:NamedThing	positive regulation of cell population proliferation	Any process that activates or increases the rate or extent of cell proliferation.	got7fsn_ti	activation of cell proliferation|up regulation of cell proliferation|up-regulation of cell proliferation|positive regulation of cell proliferation|upregulation of cell proliferation|stimulation of cell proliferation													biological_process											owl:Class	
GO:0042772	biolink:NamedThing	DNA damage response, signal transduction resulting in transcription	A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.	got7fsn_ti														biological_process											owl:Class	
GO:0061891	biolink:NamedThing	calcium ion sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).	got7fsn_ti							dph	2017-06-01T23:37:01Z						molecular_function											owl:Class	
GO:0070620	biolink:NamedThing	EGFR-Grb2-Sos complex	A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.	got7fsn_ti	Egfr-Grb2-mSos1 complex, EGF stimulated						mah	2009-04-29T04:36:30Z						cellular_component											owl:Class	
GO:0031518	biolink:NamedThing	CBF3 complex	A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.	got7fsn_ti														cellular_component											owl:Class	
GO:0048169	biolink:NamedThing	regulation of long-term neuronal synaptic plasticity	A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.	got7fsn_ti					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:1990869	biolink:NamedThing	cellular response to chemokine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.	got7fsn_ti							sl	2015-09-25T16:39:55Z						biological_process											owl:Class	
GO:0043503	biolink:NamedThing	skeletal muscle fiber adaptation	Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	got7fsn_ti	skeletal myofiber plasticity|skeletal muscle fiber plasticity|skeletal myofibre plasticity|skeletal muscle fibre plasticity													biological_process											owl:Class	
GO:0006265	biolink:NamedThing	DNA topological change	The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.	got7fsn_ti	DNA underwinding				Note that the synonym 'DNA underwinding' should not be confused with 'DNA unwinding ; GO:0006268', which refers to DNA strand separation, and is a type of geometric change. GO:0006265 refers to alteration of the superhelical density of double-stranded DNA. Note that DNA topological change and DNA geometric change (GO:0032392) are distinct, but are usually coupled in vivo.									biological_process											owl:Class	
GO:0002944	biolink:NamedThing	cyclin K-CDK12 complex	A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti	CycK/Cdk12 complex						hjd	2012-12-05T16:09:48Z						cellular_component											owl:Class	
GO:0030680	biolink:NamedThing	dimeric ribonuclease P complex	A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species.	got7fsn_ti	dimeric RNase P complex													cellular_component											owl:Class	
GO:0072584	biolink:NamedThing	caveolin-mediated endocytosis	An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers.	got7fsn_ti	caveolae-dependent endocytosis|caveolae-mediated endocytosis|caveolin-dependent endocytosis						mah	2011-02-08T04:08:33Z						biological_process											owl:Class	
GO:0006897	biolink:NamedThing	endocytosis	A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.	got7fsn_ti	vesicle endocytosis|nonselective vesicle endocytosis|plasma membrane invagination|endocytic import into cell										GO:0016196|GO:0098701|GO:0016193	Wikipedia:Endocytosis		biological_process											owl:Class	
GO:0033201	biolink:NamedThing	alpha-1,4-glucan synthase activity	Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP.	got7fsn_ti	1,4-alpha-glucan synthase activity											EC:2.4.1.21|RHEA:18189		molecular_function											owl:Class	
GO:0000461	biolink:NamedThing	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.	got7fsn_ti	endonucleolytic cleavage at site D													biological_process											owl:Class	
GO:0031949	biolink:NamedThing	regulation of glucocorticoid catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.	got7fsn_ti														biological_process											owl:Class	
GO:0018415	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide	The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide											RESID:AA0292		biological_process											owl:Class	
GO:0032810	biolink:NamedThing	sterol response element binding	Binding to a sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.	got7fsn_ti	SRE binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.									molecular_function											owl:Class	
GO:0061728	biolink:NamedThing	GDP-mannose biosynthetic process from mannose	The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.	got7fsn_ti							dph	2015-07-24T14:44:04Z						biological_process											owl:Class	
GO:0009298	biolink:NamedThing	GDP-mannose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-mannose biosynthesis|GDP-mannose anabolism|GDP-mannose synthesis|GDP-mannose formation													biological_process											owl:Class	
GO:0018535	biolink:NamedThing	nicotine dehydrogenase activity	Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor.	got7fsn_ti	nicotine:acceptor 6-oxidoreductase (hydroxylating)|nicotine oxidase activity|D-nicotine oxidase activity|nicotine:(acceptor) 6-oxidoreductase (hydroxylating)											EC:1.5.99.4|MetaCyc:NICOTINE-DEHYDROGENASE-RXN|RHEA:14769|UM-BBD_enzymeID:e0337		molecular_function											owl:Class	
GO:0072383	biolink:NamedThing	plus-end-directed vesicle transport along microtubule	The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.	got7fsn_ti	microtubule plus-end-directed vesicle localization|microtubule plus-end-directed vesicle distribution						mah	2010-12-01T04:24:51Z						biological_process											owl:Class	
GO:0047496	biolink:NamedThing	vesicle transport along microtubule	The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.	got7fsn_ti	microtubule-based vesicle localization													biological_process											owl:Class	
GO:0019914	biolink:NamedThing	cyclin-dependent protein kinase activating kinase regulator activity	Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase.	got7fsn_ti	cyclin-dependent protein kinase activating kinase, intrinsic regulator activity											EC:2.7.1.-		molecular_function											owl:Class	
GO:0030728	biolink:NamedThing	ovulation	The release of a mature ovum/oocyte from an ovary.	got7fsn_ti												Wikipedia:Ovulation		biological_process											owl:Class	
GO:0043399	biolink:NamedThing	tRNA A64-2'-O-ribosylphosphate transferase activity	Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA.	got7fsn_ti	initiator tRNA phosphoribosyl-transferase activity													molecular_function											owl:Class	
GO:0050456	biolink:NamedThing	cystine reductase activity	Catalysis of the reaction: 2 L-cysteine + NAD(+) = L-cystine + H(+) + NADH.	got7fsn_ti	NADH:L-cystine oxidoreductase activity|cystine reductase (NADH2)|NADH2:L-cystine oxidoreductase|NADH-dependent cystine reductase activity|L-cysteine:NAD+ oxidoreductase|cystine reductase (NADH) activity											MetaCyc:CYSTINE-REDUCTASE-NADH-RXN|KEGG_REACTION:R00892|EC:1.8.1.6|RHEA:20597		molecular_function											owl:Class	
GO:0031118	biolink:NamedThing	rRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0033891	biolink:NamedThing	CC-preferring endodeoxyribonuclease activity	Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.	got7fsn_ti	Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease activity|Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease activity|5'-CC-3'-preferring endodeoxyribonuclease activity|Streptomyces glaucescens exocytoplasmic endonuclease activity											MetaCyc:3.1.21.6-RXN|EC:3.1.21.6		molecular_function											owl:Class	
GO:0072092	biolink:NamedThing	ureteric bud invasion	The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.	got7fsn_ti							mah	2010-02-10T01:15:13Z						biological_process											owl:Class	
GO:0034511	biolink:NamedThing	U3 snoRNA binding	Binding to a U3 small nucleolar RNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0008115	biolink:NamedThing	sarcosine oxidase activity	Catalysis of the reaction: H(2)O + O(2) + sarcosine = formaldehyde + glycine + H(2)O(2).	got7fsn_ti	sarcosine:oxygen oxidoreductase (demethylating)											EC:1.5.3.1|RHEA:13313|KEGG_REACTION:R00610|MetaCyc:SARCOX-RXN		molecular_function											owl:Class	
GO:0060209	biolink:NamedThing	estrus	The estrous cycle phase in which a female is sexually receptive.	got7fsn_ti	oestrus				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0005737	biolink:NamedThing	cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	got7fsn_ti												Wikipedia:Cytoplasm		cellular_component											owl:Class	
GO:0047824	biolink:NamedThing	D-iditol 2-dehydrogenase activity	Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH.	got7fsn_ti												EC:1.1.1.15|MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN|RHEA:12725		molecular_function											owl:Class	
GO:0061782	biolink:NamedThing	vesicle fusion with vesicle	Fusion of the membrane of a transport vesicle with a target membrane on another vesicle.	got7fsn_ti	vesicle to vesicle fusion|vesicle-vesicle fusion						dph	2016-09-06T13:29:49Z						biological_process											owl:Class	
GO:0008798	biolink:NamedThing	beta-aspartyl-peptidase activity	Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.	got7fsn_ti	beta-aspartyl dipeptidase activity|beta-aspartyl peptidase activity											Reactome:R-HSA-5692495|EC:3.4.19.5|MetaCyc:3.4.19.5-RXN|Reactome:R-HSA-5696365		molecular_function											owl:Class	
GO:0070003	biolink:NamedThing	threonine-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.	got7fsn_ti														molecular_function											owl:Class	
GO:0102947	biolink:NamedThing	(+)-delta-cadinene-8-hydroxylase activity	Catalysis of the reaction: H+ + (+)-delta-cadinene + NADPH + O2 <=> 8-hydroxy-(+)-delta-cadinene + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-9045		molecular_function											owl:Class	
GO:0021785	biolink:NamedThing	branchiomotor neuron axon guidance	The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti	branchial motor axon guidance|BMN axon guidance|special visceral motor neuron axon guidance													biological_process											owl:Class	
GO:0008045	biolink:NamedThing	motor neuron axon guidance	The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.	got7fsn_ti	motoneuron axon guidance|motor axon pathfinding|motor axon guidance													biological_process											owl:Class	
GO:0099590	biolink:NamedThing	neurotransmitter receptor internalization	A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor.	got7fsn_ti														biological_process											owl:Class	
GO:0007289	biolink:NamedThing	spermatid nucleus differentiation	The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.	got7fsn_ti	spermatid nuclear differentiation				See also the Cell Ontology term 'spermatid ; CL:0000018'.									biological_process											owl:Class	
GO:0008263	biolink:NamedThing	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.	got7fsn_ti	G/T-mismatch-specific thymine-DNA glycosylase activity													molecular_function											owl:Class	
GO:0031037	biolink:NamedThing	myosin II filament disassembly	The disassembly of a bipolar filament composed of myosin II molecules.	got7fsn_ti	myosin II depolymerization													biological_process											owl:Class	
GO:0047434	biolink:NamedThing	indolepyruvate decarboxylase activity	Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde.	got7fsn_ti	indole-3-pyruvate decarboxylase activity|3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]|3-(indol-3-yl)pyruvate carboxy-lyase activity|indol-3-yl-pyruvate carboxy-lyase activity											EC:4.1.1.74|MetaCyc:4.1.1.74-RXN|RHEA:18017		molecular_function											owl:Class	
GO:0001059	biolink:NamedThing	transcription by RNA polymerase IV	The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter.	got7fsn_ti	transcription from RNA polymerase IV promoter|transcription from RNA pol IV promoter	https://github.com/geneontology/go-ontology/issues/14854					krc	2010-09-23T03:51:35Z						biological_process											owl:Class	
GO:0035648	biolink:NamedThing	circadian mating behavior	The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.	got7fsn_ti	circadian mating behaviour|circadian mating rhythm						bf	2011-01-25T10:20:05Z						biological_process											owl:Class	
GO:0046968	biolink:NamedThing	peptide antigen transport	The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.	got7fsn_ti														biological_process											owl:Class	
GO:0050532	biolink:NamedThing	2-phosphosulfolactate phosphatase activity	Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H(2)O = (R)-3-sulfolactate + phosphate.	got7fsn_ti	2-phosphosulpholactate phosphatase activity|(2R)-phosphosulfolactate phosphohydrolase activity|ComB phosphatase activity|(R)-2-phospho-3-sulfolactate phosphohydrolase activity											MetaCyc:R229-RXN|RHEA:23416|EC:3.1.3.71|KEGG_REACTION:R05789		molecular_function											owl:Class	
GO:0046184	biolink:NamedThing	aldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O.	got7fsn_ti	aldehyde biosynthesis|aldehyde formation|aldehyde synthesis|aldehyde anabolism													biological_process											owl:Class	
GO:0042789	biolink:NamedThing	mRNA transcription by RNA polymerase II	The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.	got7fsn_ti	mRNA transcription from Pol II promoter|mRNA transcription from RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0061784	biolink:NamedThing	peptidoglycan N-acetylglucosaminidase activity	Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan.	got7fsn_ti							dph	2016-09-07T16:17:03Z						molecular_function											owl:Class	
GO:0044599	biolink:NamedThing	AP-5 adaptor complex	An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo.	got7fsn_ti	adaptor protein-5 adaptor complex						jl	2012-05-01T03:48:11Z						cellular_component											owl:Class	
GO:0102240	biolink:NamedThing	soyasapogenol B glucuronide galactosyltransferase activity	Catalysis of the reaction: UDP-D-galactose + soyasapogenol B 3-O-beta-glucuronate <=> H+ + UDP + soyasaponin III.	got7fsn_ti												MetaCyc:RXN-12319|EC:2.4.1.272|RHEA:31487		molecular_function											owl:Class	
GO:0000342	biolink:NamedThing	RNA cap 4 binding	Binding to a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa.	got7fsn_ti														molecular_function											owl:Class	
GO:0000339	biolink:NamedThing	RNA cap binding	Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.	got7fsn_ti	snRNA cap binding|binding to mRNA cap|mRNA cap binding													molecular_function											owl:Class	
GO:0034476	biolink:NamedThing	U5 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U5 snRNA molecule.	got7fsn_ti	U5 snRNA 3' end processing													biological_process											owl:Class	
GO:0034472	biolink:NamedThing	snRNA 3'-end processing	Any process involved in forming the mature 3' end of an snRNA molecule.	got7fsn_ti	snRNA 3' end processing													biological_process											owl:Class	
GO:0075038	biolink:NamedThing	negative regulation of appressorium maturation	Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium maturation.	got7fsn_ti	negative regulation of appressorium maturation on or near host|negative regulation of maturation of appressorium on or near host													biological_process											owl:Class	
GO:0075019	biolink:NamedThing	negative regulation of appressorium formation	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation.	got7fsn_ti	negative regulation of appressorium formation on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0099022	biolink:NamedThing	vesicle tethering	The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes.  Interaction can occur via direct binding  to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0046424	biolink:NamedThing	ferulate 5-hydroxylase activity	Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+.	got7fsn_ti												MetaCyc:RXN-1121		molecular_function											owl:Class	
GO:0004085	biolink:NamedThing	butyryl-CoA dehydrogenase activity	Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein.	got7fsn_ti	butanoyl-CoA:(acceptor) 2,3-oxidoreductase activity|unsaturated acyl-CoA reductase activity|butyryl dehydrogenase activity|butanoyl-CoA:acceptor 2,3-oxidoreductase activity|unsaturated acyl coenzyme A reductase activity|short-chain acyl-coenzyme A dehydrogenase activity|3-hydroxyacyl CoA reductase activity|enoyl-coenzyme A reductase activity|short-chain-acyl-CoA dehydrogenase activity|ethylene reductase activity|butyryl coenzyme A dehydrogenase activity|short-chain acyl CoA dehydrogenase activity											EC:1.3.8.1|MetaCyc:BUTYRYL-COA-DEHYDROGENASE-RXN|UM-BBD_reactionID:r0013|KEGG_REACTION:R01178		molecular_function											owl:Class	
GO:0047114	biolink:NamedThing	kynurenate-7,8-dihydrodiol dehydrogenase activity	Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate + H(+) + NADH.	got7fsn_ti	7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase activity|7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase activity|7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase activity											EC:1.3.1.18|MetaCyc:1.3.1.18-RXN|KEGG_REACTION:R03251|RHEA:22248		molecular_function											owl:Class	
GO:0052625	biolink:NamedThing	4-aminobenzoate amino acid synthetase activity	Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate.	got7fsn_ti	pABA amino acid synthetase activity|4-aminobenzoyl amino acid synthetase activity|p-aminobenzoyl amino acid synthetase activity|p-aminobenzoate amino acid synthetase activity													molecular_function											owl:Class	
GO:0015924	biolink:NamedThing	mannosyl-oligosaccharide mannosidase activity	Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.	got7fsn_ti												EC:3.2.1.-		molecular_function											owl:Class	
GO:0072686	biolink:NamedThing	mitotic spindle	A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.	got7fsn_ti							mah	2011-07-08T05:08:16Z						cellular_component											owl:Class	
GO:0005819	biolink:NamedThing	spindle	The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.	got7fsn_ti												Wikipedia:Spindle_apparatus		cellular_component											owl:Class	
GO:0002041	biolink:NamedThing	intussusceptive angiogenesis	The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars.	got7fsn_ti														biological_process											owl:Class	
GO:0034328	biolink:NamedThing	decanoyltransferase activity	Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0044387	biolink:NamedThing	negative regulation of protein kinase activity by regulation of protein phosphorylation	The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase.	got7fsn_ti							jl	2011-12-13T04:49:36Z						biological_process											owl:Class	
GO:0006469	biolink:NamedThing	negative regulation of protein kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.	got7fsn_ti	downregulation of protein kinase activity|inhibition of protein kinase activity|down-regulation of protein kinase activity|down regulation of protein kinase activity													biological_process											owl:Class	
GO:0071669	biolink:NamedThing	plant-type cell wall organization or biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.	got7fsn_ti	plant-type cell wall organisation or biogenesis|plant-type cell wall organization and biogenesis						mah	2010-02-15T02:32:10Z						biological_process											owl:Class	
GO:0008121	biolink:NamedThing	ubiquinol-cytochrome-c reductase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+.	got7fsn_ti	complex III (mitochondrial electron transport) activity|ubiquinol-cytochrome c2 reductase activity|cytochrome|electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity|electron transporter, transferring electrons within cytochrome c oxidase complex activity|ubiquinol-cytochrome c-2 oxidoreductase activity|ubiquinol:ferricytochrome-c oxidoreductase activity|cytochrome a3/copper complex|mitochondrial electron transport complex III|ubiquinol-cytochrome c oxidoreductase activity|ubiquinone-cytochrome c reductase activity|ubiquinol-cytochrome c1 oxidoreductase activity|cytochrome b562|soluble cytochrome b562|cytochrome b566|ubiquinone--cytochrome-c oxidoreductase activity|cytochrome a|cytochrome c1|ubiquinone-cytochrome c oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/21275|https://github.com/geneontology/go-ontology/issues/20616									GO:0045154|GO:0045153	EC:7.1.1.8|Reactome:R-HSA-164651|MetaCyc:1.10.2.2-RXN|RHEA:11484		molecular_function											owl:Class	
GO:0050024	biolink:NamedThing	L-galactonolactone oxidase activity	Catalysis of the reaction: L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2) + H(+).	got7fsn_ti	L-xylono-1,4-lactone oxidase activity|L-galactono-1,4-lactone oxidase activity|L-galactono-1,4-lactone:oxygen 3-oxidoreductase activity										GO:0033733	KEGG_REACTION:R00643|MetaCyc:1.3.3.12-RXN|EC:1.3.3.12|RHEA:20617		molecular_function											owl:Class	
GO:0060612	biolink:NamedThing	adipose tissue development	The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.	got7fsn_ti	adipogenesis						dph	2009-05-15T12:36:28Z						biological_process											owl:Class	
GO:0048255	biolink:NamedThing	mRNA stabilization	Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0043489	biolink:NamedThing	RNA stabilization	Prevention of degradation of RNA molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0048829	biolink:NamedThing	root cap development	The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.	got7fsn_ti														biological_process											owl:Class	
GO:0030889	biolink:NamedThing	negative regulation of B cell proliferation	Any process that stops, prevents or reduces the rate or extent of B cell proliferation.	got7fsn_ti	negative regulation of B lymphocyte proliferation|negative regulation of B-lymphocyte proliferation|downregulation of B cell proliferation|negative regulation of B-cell proliferation|down regulation of B cell proliferation|down-regulation of B cell proliferation|inhibition of B cell proliferation													biological_process											owl:Class	
GO:0044659	biolink:NamedThing	viral release from host cell by cytolysis	The killing by a virus of a cell by means of the rupture of cell membranes and the loss of cytoplasm.	got7fsn_ti	viral release by host cell lysis|cytolysis by virus of host cell|lytic viral release|viral exit from host cell by cytolysis|viral release by cell lysis|lytic viral life cycle	https://github.com/geneontology/go-ontology/issues/18852					jl	2012-08-01T13:16:39Z			GO:0046756|GO:0019077	VZ:1077		biological_process											owl:Class	
GO:0031810	biolink:NamedThing	H4 histamine receptor binding	Binding to a H4 histamine receptor.	got7fsn_ti	H4 histamine receptor ligand													molecular_function											owl:Class	
GO:0033404	biolink:NamedThing	UUG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UUG codon.	got7fsn_ti	leucine tRNA|TTG codon-amino acid adaptor activity				Note that in the standard genetic code, TTG codes for leucine.									molecular_function											owl:Class	
GO:0102843	biolink:NamedThing	1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming)	Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												RHEA:46756|MetaCyc:RXN-8304|EC:1.14.19.42		molecular_function											owl:Class	
GO:0039614	biolink:NamedThing	induction by virus of host protein phosphorylation	Any process in which a virus activates or increases the frequency, rate or extent of phosphorylation of viral or host proteins in a host.	got7fsn_ti							bf	2012-07-06T11:15:56Z						biological_process											owl:Class	
GO:0001934	biolink:NamedThing	positive regulation of protein phosphorylation	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.	got7fsn_ti	positive regulation of protein amino acid phosphorylation|activation of protein amino acid phosphorylation|stimulation of protein amino acid phosphorylation|up-regulation of protein amino acid phosphorylation|upregulation of protein amino acid phosphorylation|up regulation of protein amino acid phosphorylation													biological_process											owl:Class	
GO:0106141	biolink:NamedThing	flavin prenyltransferase activity	Catalysis of the reaction: dimethylallylphosphate + FMNH2 = prenylated FMNH2 + phosphate.	got7fsn_ti							hjd	2018-08-17T18:50:00Z				RHEA:37743|EC:2.5.1.129		molecular_function											owl:Class	
GO:0009890	biolink:NamedThing	negative regulation of biosynthetic process	Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.	got7fsn_ti	inhibition of biosynthetic process|negative regulation of biosynthesis|negative regulation of formation|down regulation of biosynthetic process|negative regulation of anabolism|downregulation of biosynthetic process|down-regulation of biosynthetic process|negative regulation of synthesis													biological_process											owl:Class	
GO:0009892	biolink:NamedThing	negative regulation of metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.	got7fsn_ti	inhibition of organismal metabolic process|downregulation of metabolic process|negative regulation of metabolism|down-regulation of metabolic process|negative regulation of multicellular organismal metabolic process|inhibition of metabolic process|negative regulation of organismal metabolism|down regulation of metabolic process										GO:0044252			biological_process											owl:Class	
GO:0033654	biolink:NamedThing	host cell chloroplast thylakoid membrane	Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														cellular_component											owl:Class	
GO:0050506	biolink:NamedThing	vomilenine glucosyltransferase activity	Catalysis of the reaction: UDP-D-glucose + vomilenine = H(+) + raucaffricine + UDP.	got7fsn_ti	UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase activity|UDPG:vomilenine 21beta-D-glucosyltransferase activity|vomilenine-glucosyltransferase activity|UDPG:vomilenine 21-beta-D-glucosyltransferase activity											MetaCyc:2.4.1.219-RXN|RHEA:19385|EC:2.4.1.219|KEGG_REACTION:R05882		molecular_function											owl:Class	
GO:0102658	biolink:NamedThing	2-oxo-5-methylthiopentanoate aminotransferase activity	Catalysis of the reaction: 5-methylthio-2-oxopentanoate + a standard alpha amino acid <=> L-homomethionine + a 2-oxo carboxylate.	got7fsn_ti												MetaCyc:RXN-2205		molecular_function											owl:Class	
GO:0009768	biolink:NamedThing	photosynthesis, light harvesting in photosystem I	After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.	got7fsn_ti														biological_process											owl:Class	
GO:0140374	biolink:NamedThing	antiviral innate immune response	A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti							pg	2019-10-10T16:41:12Z						biological_process											owl:Class	
GO:0014826	biolink:NamedThing	vein smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.	got7fsn_ti														biological_process											owl:Class	
GO:0014829	biolink:NamedThing	vascular associated smooth muscle contraction	A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion.	got7fsn_ti	vascular smooth muscle contraction													biological_process											owl:Class	
GO:0070914	biolink:NamedThing	UV-damage excision repair	A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).	got7fsn_ti	AER|UV-damaged DNA endonuclease-dependent excision repair|alternative excision repair|UVER|UVDE-dependent excision repair						mah	2009-09-10T03:14:06Z						biological_process											owl:Class	
GO:0010192	biolink:NamedThing	mucilage biosynthetic process	The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants.	got7fsn_ti	mucilage synthesis|mucilage anabolism|mucilage formation|mucilage biosynthesis													biological_process											owl:Class	
GO:0052764	biolink:NamedThing	exo-oligoalginate lyase activity	Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.	got7fsn_ti							ai	2011-09-29T04:05:44Z				EC:4.2.2.26		molecular_function											owl:Class	
GO:0072762	biolink:NamedThing	cellular response to carbendazim	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.	got7fsn_ti							mah	2012-11-09T11:48:11Z						biological_process											owl:Class	
GO:0071407	biolink:NamedThing	cellular response to organic cyclic compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	got7fsn_ti	cellular response to organic cyclic substance						mah	2009-12-14T02:55:58Z						biological_process											owl:Class	
GO:0050641	biolink:NamedThing	6-methylsalicylic acid synthase activity	Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+).	got7fsn_ti	acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)|6-MSAS activity|MSAS activity											RHEA:12240|KEGG_REACTION:R07253|EC:2.3.1.165|MetaCyc:2.3.1.165-RXN		molecular_function											owl:Class	
GO:1901160	biolink:NamedThing	primary amino compound metabolic process	The chemical reactions and pathways involving primary amino compound.	got7fsn_ti	primary amino compound metabolism						bf	2012-07-18T04:44:39Z						biological_process											owl:Class	
GO:0030775	biolink:NamedThing	glucuronoxylan 4-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.	got7fsn_ti	S-adenosyl-L-methionine:glucuronoxylan-D-glucuronate 4-O-methyltransferase activity											RHEA:20413|EC:2.1.1.112|MetaCyc:GLUCURONOXYLAN-4-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0002139	biolink:NamedThing	stereocilia coupling link	A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle.	got7fsn_ti							hjd	2009-05-06T10:25:38Z						cellular_component											owl:Class	
GO:0021854	biolink:NamedThing	hypothalamus development	The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.	got7fsn_ti														biological_process											owl:Class	
GO:0032265	biolink:NamedThing	XMP salvage	Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0032261	biolink:NamedThing	purine nucleotide salvage	Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0072700	biolink:NamedThing	response to bismuth	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.	got7fsn_ti	response to bismuth ion						mah	2012-04-11T02:56:35Z						biological_process											owl:Class	
GO:0031855	biolink:NamedThing	oxytocin receptor binding	Binding to an oxytocin receptor.	got7fsn_ti	oxytocin receptor ligand													molecular_function											owl:Class	
GO:0036404	biolink:NamedThing	conversion of ds siRNA to ss siRNA	The process in which double-stranded small interfering RNA (ds siRNA) molecules are converted to single-stranded small interfering RNA (ss siRNA).	got7fsn_ti	conversion of double-stranded small interfering RNA to single-stranded small interfering RNA						bf	2013-08-14T14:24:19Z						biological_process											owl:Class	
GO:0031478	biolink:NamedThing	myosin VIII complex	A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.	got7fsn_ti														cellular_component											owl:Class	
GO:0046153	biolink:NamedThing	ommochrome catabolic process	The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.	got7fsn_ti	ommochrome breakdown|ommochrome degradation|ommochrome catabolism													biological_process											owl:Class	
GO:0102686	biolink:NamedThing	UDP-glucose:trans-zeatin 9-N-glucosyltransferase	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + trans-zeatin <=> H+ + 9-(alpha-D-glucosyl)-trans-zeatin + UDP(3-).	got7fsn_ti												MetaCyc:RXN-4722		molecular_function											owl:Class	
GO:0090082	biolink:NamedThing	positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway	Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	got7fsn_ti	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway|positive regulation of heart induction by negative regulation of canonical Wnt-activated signaling pathway|positive regulation of heart induction by negative regulation of canonical Wnt receptor signalling pathway						tb	2009-10-23T10:58:03Z						biological_process											owl:Class	
GO:0090090	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	got7fsn_ti	negative regulation of Wnt receptor signaling pathway through beta-catenin|negative regulation of catenin import into nucleus|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of canonical Wnt-activated signaling pathway|negative regulation of canonical Wnt receptor signalling pathway|negative regulation of catenin protein nuclear translocation						tb	2009-10-30T11:27:17Z			GO:0035414			biological_process											owl:Class	
GO:0042034	biolink:NamedThing	peptidyl-L-lysine methyl ester biosynthetic process from peptidyl-lysine	The modification of a C-terminal peptidyl-lysine to form peptidyl-L-lysine methyl ester.	got7fsn_ti	peptidyl-lysine esterification											RESID:AA0318		biological_process											owl:Class	
GO:0018350	biolink:NamedThing	protein esterification	The addition of an ester group to a protein amino acid.	got7fsn_ti	protein amino acid esterification													biological_process											owl:Class	
GO:0044331	biolink:NamedThing	cell-cell adhesion mediated by cadherin	The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.	got7fsn_ti							jl	2010-08-20T10:24:54Z						biological_process											owl:Class	
GO:0050846	biolink:NamedThing	teichuronic acid metabolic process	The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.	got7fsn_ti	teichuronic acid metabolism													biological_process											owl:Class	
GO:0031367	biolink:NamedThing	N-terminal peptidyl-glutamine deamination	The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0004394	biolink:NamedThing	heparan sulfate 2-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.	got7fsn_ti	heparan-sulfate 2-O-sulphotransferase activity|heparin 2-sulfotransferase activity|heparin-sulphate 2-sulphotransferase activity											Reactome:R-HSA-2076508|EC:2.8.2.-		molecular_function											owl:Class	
GO:0048611	biolink:NamedThing	embryonic ectodermal digestive tract development	The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.	got7fsn_ti	embryonic ectodermal gut development													biological_process											owl:Class	
GO:0048566	biolink:NamedThing	embryonic digestive tract development	The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.	got7fsn_ti	embryonic digestive tract development													biological_process											owl:Class	
GO:0050002	biolink:NamedThing	D-proline reductase (dithiol) activity	Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline.	got7fsn_ti	5-aminopentanoate:lipoate oxidoreductase (cyclizing)				Note that this function was formerly EC:1.4.4.1.							MetaCyc:1.21.4.1-RXN|EC:1.21.4.1|RHEA:12737		molecular_function											owl:Class	
GO:0048504	biolink:NamedThing	regulation of timing of animal organ formation	Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development.	got7fsn_ti	timing of organ biosynthesis|timing of organ formation													biological_process											owl:Class	
GO:0030723	biolink:NamedThing	ovarian fusome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.	got7fsn_ti	ovarian fusome organisation|ovarian fusome organization and biogenesis													biological_process											owl:Class	
GO:0045336	biolink:NamedThing	clathrin-coated phagocytic vesicle	A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.	got7fsn_ti	clathrin-coated phagosome													cellular_component											owl:Class	
GO:0014909	biolink:NamedThing	smooth muscle cell migration	The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.	got7fsn_ti														biological_process											owl:Class	
GO:0035329	biolink:NamedThing	hippo signaling	The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.	got7fsn_ti	SWH pathway|hippo signalling cascade|hippo signal transduction|Salvador-Warts-Hippo signaling pathway|hippo signaling pathway|hippo signaling cascade						bf	2010-02-26T10:43:33Z						biological_process											owl:Class	
GO:0086055	biolink:NamedThing	Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling	The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti							dph	2011-11-17T10:51:59Z						biological_process											owl:Class	
GO:0086068	biolink:NamedThing	Purkinje myocyte to ventricular cardiac muscle cell communication	The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti							dph	2011-11-22T09:14:49Z						biological_process											owl:Class	
GO:0050227	biolink:NamedThing	pteridine oxidase activity	Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown.	got7fsn_ti	2-amino-4-hydroxypteridine:oxygen oxidoreductase (7-hydroxylating)											EC:1.17.3.1|MetaCyc:PTERIDINE-OXIDASE-RXN|RHEA:12777		molecular_function											owl:Class	
GO:0046267	biolink:NamedThing	triethanolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.	got7fsn_ti	triethanolamine degradation|triethanolamine catabolism|triethanolamine breakdown													biological_process											owl:Class	
GO:0050179	biolink:NamedThing	phenylserine aldolase activity	Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine.	got7fsn_ti	L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming)|L-threo-3-phenylserine benzaldehyde-lyase activity											KEGG_REACTION:R01766|RHEA:21712|MetaCyc:PHENYLSERINE-ALDOLASE-RXN|EC:4.1.2.26		molecular_function											owl:Class	
GO:0004869	biolink:NamedThing	cysteine-type endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	got7fsn_ti	cysteine protease inhibitor activity|thiol protease inhibitor|cystatin										GO:0004870			molecular_function											owl:Class	
GO:0106227	biolink:NamedThing	peptidyl-lysine glutarylation	The glutarylation of a lysine residue in a protein.	got7fsn_ti							hjd	2019-10-17T18:57:19Z						biological_process											owl:Class	
GO:0044067	biolink:NamedThing	modification by symbiont of host intercellular junctions	The process in which a symbiont organism effects a change in the structure or function of its host intercellular junction, a specialized region of connection between two cells.	got7fsn_ti	modification of host intercellular junctions by symbiont													biological_process											owl:Class	
GO:0030699	biolink:NamedThing	glycine reductase activity	Catalysis of the reaction: acetyl phosphate + H(2)O + NH(4)(+) + thioredoxin disulfide = glycine + H(+) + phosphate + thioredoxin.	got7fsn_ti	acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming)											MetaCyc:RXN-7566|EC:1.21.4.2|RHEA:12232|KEGG_REACTION:R07226		molecular_function											owl:Class	
GO:0007258	biolink:NamedThing	JUN phosphorylation	The process of introducing a phosphate group into a JUN protein.	got7fsn_ti														biological_process											owl:Class	
GO:0002406	biolink:NamedThing	antigen sampling by M cells in mucosal-associated lymphoid tissue	The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.	got7fsn_ti	antigen sampling by M cells in MALT													biological_process											owl:Class	
GO:0002404	biolink:NamedThing	antigen sampling in mucosal-associated lymphoid tissue	The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.	got7fsn_ti	antigen transport in mucosal-associated lymphoid tissue|antigen transport in MALT|antigen sampling in MALT													biological_process											owl:Class	
GO:0034570	biolink:NamedThing	hydroxymonomethylisoproturon dimethylaminedehydrogenase activity	Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.	got7fsn_ti												EC:1.5.99.-|UM-BBD_reactionID:r0894		molecular_function											owl:Class	
GO:0046932	biolink:NamedThing	sodium-transporting ATP synthase activity, rotational mechanism	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) => ATP + H2O + Na+(in), by a rotational mechanism.	got7fsn_ti	sodium-translocating F-type ATPase activity|sodium-transporting two-sector ATPase activity	https://github.com/geneontology/go-ontology/issues/19380|https://github.com/geneontology/go-ontology/issues/21796										RHEA:58158|RHEA:58156|EC:7.2.2.1|TC:3.A.2.1.2|MetaCyc:3.6.3.15-RXN		molecular_function											owl:Class	
GO:0015081	biolink:NamedThing	sodium ion transmembrane transporter activity	Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.	got7fsn_ti	sodium transporter activity										GO:0022816			molecular_function											owl:Class	
GO:0097354	biolink:NamedThing	prenylation	The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added.	got7fsn_ti							pr	2012-07-03T01:12:19Z						biological_process											owl:Class	
GO:0008458	biolink:NamedThing	carnitine O-octanoyltransferase activity	Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA.	got7fsn_ti	carnitine medium-chain acyltransferase activity|octanoyl-CoA:L-carnitine O-octanoyltransferase activity|overt mitochondrial carnitine palmitoyltransferase|medium-chain/long-chain carnitine acyltransferase activity|easily solubilized mitochondrial carnitine palmitoyltransferase											RHEA:17177|Reactome:R-HSA-390281|KEGG_REACTION:R03779|EC:2.3.1.137|MetaCyc:CARNITINE-O-OCTANOYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0016406	biolink:NamedThing	carnitine O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:1904667	biolink:NamedThing	negative regulation of ubiquitin protein ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity.	got7fsn_ti	negative regulation of APC-Cdc20 complex activity|down-regulation of protein ubiquitination activity|negative regulation of APC/C activity during mitotic cell cycle|downregulation of protein ubiquitination activity|down regulation of ubiquitin protein ligase activity|inhibition of ubiquitin protein ligase activity|negative regulation of E3|downregulation of ubiquitin protein ligase activity|down-regulation of E3|inhibition of E3|negative regulation of mitotic anaphase-promoting complex activity|negative regulation of protein ubiquitination activity|negative regulation of cyclosome activity during mitotic cell cycle|downregulation of E3|down regulation of ubiquitin ligase activity|down regulation of protein ubiquitination activity|down-regulation of ubiquitin protein ligase activity|negative regulation of ubiquitin ligase activity|down-regulation of ubiquitin ligase activity|negative regulation of APC activity during mitotic cell cycle|inhibition of protein ubiquitination activity|down regulation of E3|negative regulation of APC-fizzy related complex activity|inhibition of ubiquitin ligase activity|downregulation of ubiquitin ligase activity|negative regulation of anaphase-promoting complex activity during mitotic cell cycle						dph	2015-09-08T15:27:05Z			GO:1904190|GO:0060564			biological_process											owl:Class	
GO:0000257	biolink:NamedThing	nitrilase activity	Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.	got7fsn_ti	nitrile aminohydrolase activity|benzonitrilase activity|acetonitrilase activity											UM-BBD_enzymeID:e0283|MetaCyc:3.5.5.1-RXN|RHEA:21724|KEGG_REACTION:R00540|EC:3.5.5.1		molecular_function											owl:Class	
GO:0034405	biolink:NamedThing	response to fluid shear stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.	got7fsn_ti														biological_process											owl:Class	
GO:0047609	biolink:NamedThing	acetylputrescine deacetylase activity	Catalysis of the reaction: N-acetylputrescine + H(2)O = acetate + putrescine.	got7fsn_ti	N-acetylputrescine acetylhydrolase activity											EC:3.5.1.62|MetaCyc:ACETYLPUTRESCINE-DEACETYLASE-RXN|KEGG_REACTION:R01156|RHEA:23412		molecular_function											owl:Class	
GO:0044178	biolink:NamedThing	host cell Golgi membrane	The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus.	got7fsn_ti	host Golgi membrane						jl	2009-09-04T03:16:14Z						cellular_component											owl:Class	
GO:0003045	biolink:NamedThing	regulation of systemic arterial blood pressure by physical factors	The regulation of blood pressure mediated by detection of forces within the circulatory system.	got7fsn_ti	blood pressure regulation by physical factors													biological_process											owl:Class	
GO:0003073	biolink:NamedThing	regulation of systemic arterial blood pressure	The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.	got7fsn_ti														biological_process											owl:Class	
GO:0032254	biolink:NamedThing	establishment of secretory granule localization	The directed movement of a secretory granule to a specific location.	got7fsn_ti	establishment of secretory granule localisation													biological_process											owl:Class	
GO:0102894	biolink:NamedThing	UDPG:cyclo-DOPA 5-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + leucodopachrome <=> H+ + cyclo-dopa 5-O-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-8481		molecular_function											owl:Class	
GO:0072051	biolink:NamedThing	juxtaglomerular apparatus development	The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.	got7fsn_ti							mah	2010-01-25T03:52:23Z						biological_process											owl:Class	
GO:0021948	biolink:NamedThing	inward migration of deep nuclear neurons	The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position.	got7fsn_ti														biological_process											owl:Class	
GO:0032477	biolink:NamedThing	homodimeric decaprenyl diphosphate synthase complex	A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0032476	biolink:NamedThing	decaprenyl diphosphate synthase complex	A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0040002	biolink:NamedThing	collagen and cuticulin-based cuticle development	Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.	got7fsn_ti	collagen and cuticulin-based cuticle formation|collagen and cuticulin-based cuticle biosynthetic process|collagen and cuticulin-based cuticle anabolism|collagen and cuticulin-based cuticle synthesis													biological_process											owl:Class	
GO:0042335	biolink:NamedThing	cuticle development	The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.	got7fsn_ti	cuticle formation|cuticle biosynthesis|cuticle anabolism|cuticle biosynthetic process|cuticle synthesis													biological_process											owl:Class	
GO:0050990	biolink:NamedThing	N-terminal protein amino acid carbamoylation	The carbamoylation of the N-terminal amino acid of proteins.	got7fsn_ti	N-terminal protein amino acid carbamylation													biological_process											owl:Class	
GO:0048719	biolink:NamedThing	epistomal sclerite morphogenesis	The process in which the anatomical structures of the epistomal sclerite are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0052790	biolink:NamedThing	chitooligosaccharide deacetylase activity	Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions.	got7fsn_ti							ai	2011-10-04T03:48:35Z				EC:3.5.1.-		molecular_function											owl:Class	
GO:0006121	biolink:NamedThing	mitochondrial electron transport, succinate to ubiquinone	The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.	got7fsn_ti	complex II (succinate to ubiquinone)|oxidative phosphorylation, succinate to ubiquinone|mitochondrial electron transport, succinate to coenzyme Q													biological_process											owl:Class	
GO:0042649	biolink:NamedThing	prothylakoid	Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light.	got7fsn_ti														cellular_component											owl:Class	
GO:0031976	biolink:NamedThing	plastid thylakoid	Any thylakoid within a plastid.	got7fsn_ti														cellular_component											owl:Class	
GO:0070619	biolink:NamedThing	Shc-Grb2-Sos complex	A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.	got7fsn_ti	Shc-Grb2-mSos1 complex, EGF stimulated						mah	2009-04-29T04:30:00Z						cellular_component											owl:Class	
GO:0034679	biolink:NamedThing	integrin alpha9-beta1 complex	An integrin complex that comprises one alpha9 subunit and one beta1 subunit.	got7fsn_ti	ITGA9-ITGB1 complex|alpha9-beta1 integrin complex													cellular_component											owl:Class	
GO:0031833	biolink:NamedThing	type 7 serotonin receptor binding	Binding to a type 7 serotonin receptor.	got7fsn_ti	5-hydroxytryptamine 7 receptor binding|type 7 serotonin receptor ligand													molecular_function											owl:Class	
GO:0060333	biolink:NamedThing	interferon-gamma-mediated signaling pathway	A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.	got7fsn_ti	type II IFN-mediated signaling pathway|type II interferon-mediated signaling pathway|immune interferon signaling pathway|interferon-gamma-mediated signalling pathway|gamma-interferon-mediated signaling pathway													biological_process											owl:Class	
GO:0019475	biolink:NamedThing	L-lysine catabolic process to acetate	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate.	got7fsn_ti	lysine fermentation|L-lysine breakdown to acetate|L-lysine degradation to acetate											MetaCyc:P163-PWY		biological_process											owl:Class	
GO:0047914	biolink:NamedThing	gamma-glutamylhistamine synthase activity	Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown.	got7fsn_ti	g-glutamylhistamine synthase activity|gamma-glutaminylhistamine synthetase activity|L-glutamate:histamine ligase activity|gamma-GHA synthetase activity											EC:6.3.2.18|RHEA:18881|MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0036482	biolink:NamedThing	neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron in response to hydrogen peroxide.	got7fsn_ti	H2O2-induced neuron intrinsic apoptotic signaling pathway|hydrogen peroxide-induced neuronal apoptosis|neuron intrinsic apoptotic signaling pathway in response to H2O2|hydrogen peroxide-induced neuron apoptosis|neuron apoptosis in response to hydrogen peroxide						bf	2014-08-14T13:23:32Z						biological_process											owl:Class	
GO:0036480	biolink:NamedThing	neuron intrinsic apoptotic signaling pathway in response to oxidative stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	oxidative stress-induced neuron apoptosis|oxidative stress-induced neuronal apoptosis|neuron apoptosis in response to oxidative stress						bf	2014-08-14T13:13:44Z						biological_process											owl:Class	
GO:0047194	biolink:NamedThing	indoleacetylglucose-inositol O-acyltransferase activity	Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose.	got7fsn_ti	1-O-(indol-3-ylacetyl)-beta-D-glucose:myo-inositol indole-3-ylacetyltransferase activity|indole-3-acetyl-beta-1-D-glucoside:myo-inositol indoleacetyltransferase activity|1-O-(indol-3-yl)acetyl-beta-D-glucose:myo-inositol (indol-3-yl)acetyltransferase activity											KEGG_REACTION:R04333|MetaCyc:2.3.1.72-RXN|RHEA:21180|EC:2.3.1.72		molecular_function											owl:Class	
GO:0003884	biolink:NamedThing	D-amino-acid oxidase activity	Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.	got7fsn_ti	new yellow enzyme|L-amino acid:O2 oxidoreductase activity|D-amino-acid:oxygen oxidoreductase (deaminating)											Reactome:R-HSA-389821|MetaCyc:D-AMINO-ACID-OXIDASE-RXN|EC:1.4.3.3|RHEA:21816		molecular_function											owl:Class	
GO:0097373	biolink:NamedThing	MCM core complex	A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated.	got7fsn_ti	MCM4/6/7 complex						pr	2012-09-12T10:41:42Z						cellular_component											owl:Class	
GO:1903445	biolink:NamedThing	protein transport from ciliary membrane to plasma membrane	The directed movement of protein from ciliary membrane to plasma membrane.	got7fsn_ti							pr	2014-09-18T07:46:10Z						biological_process											owl:Class	
GO:0061794	biolink:NamedThing	conidium development	The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	got7fsn_ti							dph	2016-09-17T09:53:51Z						biological_process											owl:Class	
GO:0010698	biolink:NamedThing	acetyltransferase activator activity	Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.	got7fsn_ti	acetyltransferase stimulator activity													molecular_function											owl:Class	
GO:0015722	biolink:NamedThing	canalicular bile acid transport	Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.	got7fsn_ti														biological_process											owl:Class	
GO:0035088	biolink:NamedThing	establishment or maintenance of apical/basal cell polarity	Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.	got7fsn_ti														biological_process											owl:Class	
GO:0050104	biolink:NamedThing	L-gulonate 3-dehydrogenase activity	Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH.	got7fsn_ti	L-3-aldonic dehydrogenase activity|L-gulonic acid dehydrogenase activity|L-beta-hydroxyacid dehydrogenase activity|L-gulonate:NAD+ 3-oxidoreductase activity|L-3-aldonate dehydrogenase activity|L-beta-hydroxy-acid-NAD-oxidoreductase activity|L-3-hydroxyacid dehydrogenase activity											RHEA:12889|Reactome:R-HSA-5661290|MetaCyc:L-GULONATE-3-DEHYDROGENASE-RXN|KEGG_REACTION:R02640|EC:1.1.1.45		molecular_function											owl:Class	
GO:0047355	biolink:NamedThing	CDP-glycerol glycerophosphotransferase activity	Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP.	got7fsn_ti	poly(glycerol phosphate) polymerase activity|CGPTase activity|CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase activity|teichoic-acid synthase activity|CDPglycerol glycerophosphotransferase activity|teichoic acid glycerol transferase activity|glycerophosphate synthetase activity|cytidine diphosphoglycerol glycerophosphotransferase activity											MetaCyc:2.7.8.12-RXN|EC:2.7.8.12|RHEA:13565		molecular_function											owl:Class	
GO:0102937	biolink:NamedThing	16-alpha-hydroxygypsogenate-UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 16-alpha-hydroxygypsogenate = 16-alpha-hydroxygypsogenate-28-beta-D-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-9014		molecular_function											owl:Class	
GO:0072240	biolink:NamedThing	metanephric DCT cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state.	got7fsn_ti	metanephric distal convoluted tubule cell differentiation						mah	2010-03-19T03:24:25Z						biological_process											owl:Class	
GO:0016622	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome.	got7fsn_ti												EC:1.2.2.-		molecular_function											owl:Class	
GO:0021658	biolink:NamedThing	rhombomere 3 morphogenesis	The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0036140	biolink:NamedThing	peptidyl-asparagine 3-dioxygenase activity	Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2.	got7fsn_ti							bf	2012-03-07T09:27:44Z						molecular_function											owl:Class	
GO:0035529	biolink:NamedThing	NADH pyrophosphatase activity	Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+.	got7fsn_ti	NADH diphosphatase activity|NADH pyrophosphohydrolase activity						bf	2010-05-05T04:55:10Z				EC:3.6.1.9|KEGG_REACTION:R00103|MetaCyc:RXN0-4401|Reactome:R-HSA-6809287		molecular_function											owl:Class	
GO:0044751	biolink:NamedThing	cellular response to human chorionic gonadotropin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.	got7fsn_ti	cellular response to human chorionic gonadotrophin stimulus						jl	2012-11-20T16:19:45Z						biological_process											owl:Class	
GO:0044752	biolink:NamedThing	response to human chorionic gonadotropin	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.	got7fsn_ti	response to human chorionic gonadotropin stimulus						jl	2012-11-20T16:21:08Z						biological_process											owl:Class	
GO:0009444	biolink:NamedThing	pyruvate oxidation	The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate.	got7fsn_ti												Wikipedia:Pyruvate_decarboxylation|MetaCyc:PYRUVOX-PWY		biological_process											owl:Class	
GO:0006090	biolink:NamedThing	pyruvate metabolic process	The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.	got7fsn_ti	pyruvate metabolism|pyruvate dehydrogenase bypass										GO:0006087	MetaCyc:P41-PWY|Wikipedia:Pyruvic_acid		biological_process											owl:Class	
GO:0080047	biolink:NamedThing	GDP-L-galactose phosphorylase activity	Catalysis of the reaction: GDP-L-galactose + phosphate = L-galactose-1-P + GDP.	got7fsn_ti												MetaCyc:RXNQT-4141|RHEA:27698|EC:2.7.7.69		molecular_function											owl:Class	
GO:0030595	biolink:NamedThing	leukocyte chemotaxis	The movement of a leukocyte in response to an external stimulus.	got7fsn_ti	leucocyte chemotaxis|immune cell chemotaxis													biological_process											owl:Class	
GO:0071784	biolink:NamedThing	endoplasmic reticulum cisternal network assembly	The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.	got7fsn_ti	ER cisternal network assembly|endoplasmic reticulum cisternal network formation|ER cisternal network formation						mah	2010-09-01T01:50:49Z						biological_process											owl:Class	
GO:0007490	biolink:NamedThing	tergite morphogenesis	The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment.	got7fsn_ti														biological_process											owl:Class	
GO:0014891	biolink:NamedThing	striated muscle atrophy	A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.	got7fsn_ti														biological_process											owl:Class	
GO:0014889	biolink:NamedThing	muscle atrophy	A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.	got7fsn_ti					GO:0014889 should only be used for annotation when muscle atrophy is a normal physiological process and not a disease process.							Wikipedia:Muscle_atrophy		biological_process											owl:Class	
GO:0008275	biolink:NamedThing	gamma-tubulin small complex	A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex.	got7fsn_ti	gamma-tubulin small complex, spindle pole body|Tub4 complex|gammaTuSC|gamma-tubulin small complex, mitotic spindle pole body|gamma-tubulin small complex, centrosomal	https://github.com/geneontology/go-ontology/issues/20967									GO:0000927|GO:0000928|GO:0061495			cellular_component											owl:Class	
GO:1990950	biolink:NamedThing	metaphase/anaphase transition of meiosis II	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II.	got7fsn_ti	second meiotic metaphase/anaphase transition|meiosis II metaphase/anaphase transition						mah	2016-04-25T15:28:51Z						biological_process											owl:Class	
GO:0008804	biolink:NamedThing	carbamate kinase activity	Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate.	got7fsn_ti	carbamoyl phosphokinase activity|carbamyl phosphokinase activity|ATP:carbamate phosphotransferase activity|CKase activity											RHEA:10152|MetaCyc:CARBAMATE-KINASE-RXN|EC:2.7.2.2		molecular_function											owl:Class	
GO:0050297	biolink:NamedThing	stizolobate synthase activity	Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.	got7fsn_ti	3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing)											EC:1.13.11.29|MetaCyc:STIZOLOBATE-SYNTHASE-RXN|RHEA:21220		molecular_function											owl:Class	
GO:0070033	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).	got7fsn_ti	SNARE complex (Vamp2, Snap25, Stx1a, Cplx2)|Vamp2-Snap25-Stx1a-Cplx2 complex													cellular_component											owl:Class	
GO:0044766	biolink:NamedThing	multi-organism transport	The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism.	got7fsn_ti							jl	2012-12-13T16:25:50Z						biological_process											owl:Class	
GO:0052612	biolink:NamedThing	adonirubin 3-hydroxylase activity	Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O.	got7fsn_ti	beta-carotene hydroxylase activity|carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity											MetaCyc:RXN-8187		molecular_function											owl:Class	
GO:1990514	biolink:NamedThing	5' transitive RNA interference	An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.	got7fsn_ti							jl	2014-10-09T15:29:31Z						biological_process											owl:Class	
GO:0036453	biolink:NamedThing	transitive RNA interference	An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence.	got7fsn_ti	transitive RNAi						bf	2013-11-07T11:14:03Z						biological_process											owl:Class	
GO:0017002	biolink:NamedThing	activin-activated receptor activity	Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta.	got7fsn_ti	activin receptor activity				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand activin. For binding to other extracellular ligands, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.									molecular_function											owl:Class	
GO:0005001	biolink:NamedThing	transmembrane receptor protein tyrosine phosphatase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0019198	biolink:NamedThing	transmembrane receptor protein phosphatase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0070741	biolink:NamedThing	response to interleukin-6	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.	got7fsn_ti	response to IL-6						mah	2009-06-19T03:39:12Z						biological_process											owl:Class	
GO:0006499	biolink:NamedThing	N-terminal protein myristoylation	The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0006498	biolink:NamedThing	N-terminal protein lipidation	The covalent attachment of a lipid group to the amino terminus of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0047393	biolink:NamedThing	glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity	Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H(2)O = glycerol 1-phosphate + H(+).	got7fsn_ti	rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase activity|rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase activity											RHEA:16493|MetaCyc:3.1.4.42-RXN|EC:3.1.4.42|KEGG_REACTION:R02648		molecular_function											owl:Class	
GO:0031681	biolink:NamedThing	G-protein beta-subunit binding	Binding to a G-protein beta subunit.	got7fsn_ti	G-beta protein subunit binding													molecular_function											owl:Class	
GO:1902712	biolink:NamedThing	G protein-coupled GABA receptor complex	A protein complex which is capable of G protein-coupled GABA receptor activity. In human, it is usually a heterodimer composed of GABA-B receptor subunits 1 and 2.	got7fsn_ti	G-protein coupled GABA receptor complex				An example of this is GABR1 in human (UniProt symbol Q9UBS5) in PMID:18790874.		bhm	2014-02-21T09:47:03Z						cellular_component											owl:Class	
GO:0034571	biolink:NamedThing	4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity	Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid.	got7fsn_ti												UM-BBD_reactionID:r0895		molecular_function											owl:Class	
GO:0102762	biolink:NamedThing	eriodictyol 4'-O-methyltransferase activity	Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine  <=> H+ + hesperetin(1-) + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-7754		molecular_function											owl:Class	
GO:0050830	biolink:NamedThing	defense response to Gram-positive bacterium	Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.	got7fsn_ti	defense response to Gram-positive bacteria|defence response to Gram-positive bacteria|defence response to Gram-positive bacterium|Gram-positive antibacterial peptide activity													biological_process											owl:Class	
GO:0042742	biolink:NamedThing	defense response to bacterium	Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.	got7fsn_ti	resistance response to pathogenic bacteria|defence response to bacteria|defense response to bacterium, incompatible interaction|resistance response to pathogenic bacterium|defence response to bacterium|defense response to bacteria|antibacterial peptide activity										GO:0009816|GO:0042830			biological_process											owl:Class	
GO:0071982	biolink:NamedThing	maintenance of diapause	The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.	got7fsn_ti							mah	2010-10-21T04:46:32Z						biological_process											owl:Class	
GO:0004329	biolink:NamedThing	formate-tetrahydrofolate ligase activity	Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.	got7fsn_ti	10-formyltetrahydrofolate synthetase activity|10-formyl-THF synthetase activity|formyltetrahydrofolate synthetase activity|tetrahydrofolate formylase activity|formate:tetrahydrofolate ligase (ADP-forming)|tetrahydrofolic formylase activity											MetaCyc:FORMATETHFLIG-RXN|RHEA:20221|Reactome:R-HSA-6801456|Reactome:R-HSA-5696839|Reactome:R-HSA-200711|EC:6.3.4.3		molecular_function											owl:Class	
GO:0015844	biolink:NamedThing	monoamine transport	The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti											GO:0015873			biological_process											owl:Class	
GO:0033542	biolink:NamedThing	fatty acid beta-oxidation, unsaturated, even number	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	got7fsn_ti												MetaCyc:PWY-5138		biological_process											owl:Class	
GO:0047358	biolink:NamedThing	UDP-glucose-glycoprotein glucose phosphotransferase activity	Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP.	got7fsn_ti	UDPglucose:glycoprotein-D-mannose glucosephosphotransferase activity|UDP-glucose:glycoprotein-D-mannose glucosephosphotransferase activity|UDPglucose-glycoprotein glucose phosphotransferase activity|Glc-phosphotransferase activity|uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase activity|UDP-glucose:glycoprotein glucose-1-phosphotransferase activity|GlcPTase activity											RHEA:20181|MetaCyc:2.7.8.19-RXN|EC:2.7.8.19		molecular_function											owl:Class	
GO:0040010	biolink:NamedThing	positive regulation of growth rate	Any process that increases the rate of growth of all or part of an organism.	got7fsn_ti	stimulation of growth rate|up-regulation of growth rate|upregulation of growth rate|up regulation of growth rate|activation of growth rate				Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation.									biological_process											owl:Class	
GO:0007120	biolink:NamedThing	axial cellular bud site selection	The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell.	got7fsn_ti	axial bud site selection|axial budding													biological_process											owl:Class	
GO:0000282	biolink:NamedThing	cellular bud site selection	The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	bud site selection/establishment of cell polarity				Note that this term was split from 'bud site selection/establishment of cell polarity (sensu Saccharomyces) ; GO:0007115' (a sibling term, 'establishment of cell polarity (sensu Saccharomyces) ; GO:0000283', was created but has since been merged with 'establishment of cell polarity' ; GO:0030010).									biological_process											owl:Class	
GO:1903941	biolink:NamedThing	negative regulation of respiratory gaseous exchange	Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange.	got7fsn_ti	down-regulation of respiratory gaseous exchange|down regulation of respiratory gaseous exchange|downregulation of respiratory gaseous exchange|inhibition of respiratory gaseous exchange						sl	2015-02-17T20:26:24Z						biological_process											owl:Class	
GO:0071768	biolink:NamedThing	mycolic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.	got7fsn_ti	mycolic acid synthesis|mycolic acid formation|mycolic acid anabolism|mycolate biosynthetic process|mycolic acid biosynthesis						mah	2010-03-29T04:36:10Z				MetaCyc:PWYG-321		biological_process											owl:Class	
GO:0060741	biolink:NamedThing	prostate gland stromal morphogenesis	The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.	got7fsn_ti							dph	2009-06-16T09:27:01Z						biological_process											owl:Class	
GO:0048894	biolink:NamedThing	efferent axon development in a lateral line nerve	The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0021955	biolink:NamedThing	central nervous system neuron axonogenesis	Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.	got7fsn_ti														biological_process											owl:Class	
GO:0008058	biolink:NamedThing	ocellus pigment granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.	got7fsn_ti	ocellus pigment granule organization and biogenesis|ocellus pigment granule organisation													biological_process											owl:Class	
GO:0048753	biolink:NamedThing	pigment granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule.	got7fsn_ti	pigment granule organisation|pigment granule organization and biogenesis													biological_process											owl:Class	
GO:0031462	biolink:NamedThing	Cul2-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.	got7fsn_ti	EC2S complex|VBC complex|CRL2 complex|cullin-RING ligase 2|SCF2 complex|ECS complex|CDL2 complex|CBC complex													cellular_component											owl:Class	
GO:0050635	biolink:NamedThing	acridone synthase activity	Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H(+) + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO(2) + 4 CoA + H(2)O.	got7fsn_ti	malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing)											EC:2.3.1.159|KEGG_REACTION:R07250|MetaCyc:2.3.1.159-RXN|RHEA:22224		molecular_function											owl:Class	
GO:0033532	biolink:NamedThing	stachyose biosynthetic process	The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	stachyose synthesis|stachyose anabolism|stachyose formation|stachyose biosynthesis											MetaCyc:PWY-5337		biological_process											owl:Class	
GO:0010325	biolink:NamedThing	raffinose family oligosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization).	got7fsn_ti	raffinose family oligosaccharide biosynthesis													biological_process											owl:Class	
GO:0030011	biolink:NamedThing	maintenance of cell polarity	The maintenance of established anisotropic intracellular organization or cell growth patterns.	got7fsn_ti											GO:0030469|GO:0030013			biological_process											owl:Class	
GO:2001080	biolink:NamedThing	chitosan binding	Binding to chitosan.	got7fsn_ti							jl	2011-09-15T01:17:32Z						molecular_function											owl:Class	
GO:0021794	biolink:NamedThing	thalamus development	The process in which the thalamus changes over time, from its initial formation to its mature state.	got7fsn_ti														biological_process											owl:Class	
GO:0006983	biolink:NamedThing	ER overload response	The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB.	got7fsn_ti	EOR|EOR-mediated activation of NF-kappaB|ER-overload response|EOR-mediated NF-kappaB activation|endoplasmic reticulum overload response|positive regulation of NF-kappaB transcription factor activity by ER overload response|positive regulation of NF-kappaB transcription factor activity by EOR										GO:0006985			biological_process											owl:Class	
GO:0048162	biolink:NamedThing	multi-layer follicle stage	The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.	got7fsn_ti	mammalian oogenesis stage 5													biological_process											owl:Class	
GO:0010501	biolink:NamedThing	RNA secondary structure unwinding	The process in which a secondary structure of RNA are broken or 'melted'.	got7fsn_ti	RNA duplex unwinding													biological_process											owl:Class	
GO:0015275	biolink:NamedThing	stretch-activated, cation-selective, calcium channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching.	got7fsn_ti														molecular_function											owl:Class	
GO:0008381	biolink:NamedThing	mechanosensitive ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress.	got7fsn_ti	mechanically gated channel activity|mechanically-gated ion channel activity|mechanically-gated channel activity										GO:0022833	TC:1.A.23.2.1		molecular_function											owl:Class	
GO:0004482	biolink:NamedThing	mRNA (guanine-N7-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.	got7fsn_ti	messenger RNA guanine 7-methyltransferase activity|guanine-7-methyltransferase activity|S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase activity|messenger ribonucleate guanine 7-methyltransferase activity|S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase activity											Reactome:R-HSA-77090|Reactome:R-HSA-9694737|Reactome:R-HSA-9684016|Reactome:R-HSA-9694476|MetaCyc:MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|Reactome:R-HSA-9684018|Reactome:R-HSA-9694492|Reactome:R-HSA-9684017|EC:2.1.1.56		molecular_function											owl:Class	
GO:0071735	biolink:NamedThing	IgG immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	IgG1|IgG2b|IgG3|IgG2|IgG2c|IgG4|IgG2a				Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0120232	biolink:NamedThing	prenyl-FMNH2 biosynthetic process	The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1.	got7fsn_ti	prenylated FMNH2 anabolism|prenylated FMNH2 synthesis|prenylated FMNH2 biosynthetic process|prenyl-FMNH2 formation|prenylated FMNH2 biosynthesis|prenylated FMNH2 formation|prenyl-FMNH2 anabolism|prenyl-FMNH2 biosynthesis|prenyl-FMNH2 synthesis	https://github.com/geneontology/go-ontology/issues/19244					krc	2020-06-30T19:09:11Z						biological_process											owl:Class	
GO:0090562	biolink:NamedThing	protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in).	got7fsn_ti							tb	2014-04-08T14:55:02Z						molecular_function											owl:Class	
GO:0030890	biolink:NamedThing	positive regulation of B cell proliferation	Any process that activates or increases the rate or extent of B cell proliferation.	got7fsn_ti	up-regulation of B cell proliferation|positive regulation of B lymphocyte proliferation|upregulation of B cell proliferation|up regulation of B cell proliferation|activation of B cell proliferation|positive regulation of B-cell proliferation|positive regulation of B-lymphocyte proliferation|stimulation of B cell proliferation													biological_process											owl:Class	
GO:0008676	biolink:NamedThing	3-deoxy-8-phosphooctulonate synthase activity	Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate.	got7fsn_ti	phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating) activity|3-deoxy-D-mannooctulosonate-8-phosphate synthetase activity|2-keto-3-deoxy-8-phosphooctonic synthetase activity|KDOP synthase activity|3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity|3-deoxyoctulosonic 8-phosphate synthetase activity|KDO-8-phosphate synthetase activity|2-dehydro-3-deoxyphosphooctonate aldolase activity|KDO-8-P synthase activity|3-deoxy-D-manno-octulosonate-8-phosphate synthase activity|2-dehydro-3-deoxy-phosphooctonate aldolase activity|phospho-2-keto-3-deoxyoctonate aldolase activity				Note that this function was formerly EC:4.1.2.16.							EC:2.5.1.55|KEGG_REACTION:R03254|MetaCyc:KDO-8PSYNTH-RXN|RHEA:14053		molecular_function											owl:Class	
GO:0048855	biolink:NamedThing	adenohypophysis morphogenesis	The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.	got7fsn_ti	anterior pituitary morphogenesis|adenophysis morphogenesis|anterior pituitary gland morphogenesis													biological_process											owl:Class	
GO:0051261	biolink:NamedThing	protein depolymerization	The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.	got7fsn_ti	protein polymer catabolic process|protein polymer breakdown|protein polymer catabolism|protein polymer degradation													biological_process											owl:Class	
GO:0042204	biolink:NamedThing	s-triazine compound catabolic process	The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.	got7fsn_ti	s-triazine compound degradation|s-triazine compound catabolism|s-triazine compound breakdown											UM-BBD_pathwayID:tria		biological_process											owl:Class	
GO:0004109	biolink:NamedThing	coproporphyrinogen oxidase activity	Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX.	got7fsn_ti	coproporphyrinogenase activity|coprogen oxidase activity|coproporphyrinogen:oxygen oxidoreductase (decarboxylating)|coproporphyrinogen-III oxidase activity											RHEA:18257|Reactome:R-HSA-189421|MetaCyc:RXN0-1461|KEGG_REACTION:R03220|EC:1.3.3.3		molecular_function											owl:Class	
GO:0002127	biolink:NamedThing	tRNA wobble base cytosine methylation	The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position.	got7fsn_ti	wobble position m5C biosynthesis													biological_process											owl:Class	
GO:0033076	biolink:NamedThing	isoquinoline alkaloid metabolic process	The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.	got7fsn_ti	isoquinoline alkaloid metabolism|ipecac alkaloid metabolism													biological_process											owl:Class	
GO:0038150	biolink:NamedThing	C-C chemokine receptor CCR2 signaling pathway	A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR2) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	C-C chemokine receptor type 2 signaling pathway						bf	2012-05-11T11:41:02Z						biological_process											owl:Class	
GO:0044293	biolink:NamedThing	dendriole	Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC).	got7fsn_ti							jl	2010-02-04T03:32:02Z				NIF_Subcellular:sao295057932|NIF_Subcellular:sao28175134		cellular_component											owl:Class	
GO:0044292	biolink:NamedThing	dendrite terminus	A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole.	got7fsn_ti	dendrite terminal specialization|terminal specialization of a dendrite|terminal specialization|dendrite terminal						jl	2010-02-04T03:14:37Z				NIF_Subcellular:sao28175134		cellular_component											owl:Class	
GO:0008907	biolink:NamedThing	integrase activity	Catalysis of the integration of one DNA segment into another.	got7fsn_ti												Reactome:R-HSA-164523		molecular_function											owl:Class	
GO:0005123	biolink:NamedThing	death receptor binding	Binding to a member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).	got7fsn_ti	EDAR binding|TNFR1 binding|death receptor interacting protein activity|death receptor-associated factor activity|APO binding|death receptor ligand|KILLER binding|NGFR binding|death receptor adaptor protein activity|FAS binding|DR binding|TRAIL binding													molecular_function											owl:Class	
GO:0047690	biolink:NamedThing	aspartyltransferase activity	Catalysis of the reaction: L-asparagine + H(+) + hydroxylamine = beta-L-aspartylhydroxamate + NH(4)(+).	got7fsn_ti	beta-aspartyl transferase activity|aspartotransferase activity|L-asparagine:hydroxylamine gamma-aspartyltransferase activity											KEGG_REACTION:R01485|RHEA:11252|MetaCyc:ASPARTYLTRANSFERASE-RXN|EC:2.3.2.7		molecular_function											owl:Class	
GO:0044416	biolink:NamedThing	induction by symbiont of host defense response	The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host defense response|upregulation by symbiont of host defense response|positive regulation by organism of defense response of other organism involved in symbiotic interaction|induction by organism of defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host defense response|activation by symbiont of host defense response|activation of host defense response|up-regulation by symbiont of host defense response|stimulation by symbiont of host defense response										GO:0052509|GO:0052251|GO:0052510			biological_process											owl:Class	
GO:0002025	biolink:NamedThing	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change.	got7fsn_ti	noradrenaline-adrenaline vasodilation involved in regulation of blood pressure|vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|norepinephrine-epinephrine vasodilation during blood pressure regulation													biological_process											owl:Class	
GO:0019438	biolink:NamedThing	aromatic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.	got7fsn_ti	aromatic compound formation|aromatic hydrocarbon biosynthesis|aromatic compound biosynthesis|aromatic compound anabolism|aromatic compound synthesis|aromatic hydrocarbon biosynthetic process													biological_process											owl:Class	
GO:0008583	biolink:NamedThing	mystery cell differentiation	The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0033014	biolink:NamedThing	tetrapyrrole biosynthetic process	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.	got7fsn_ti	tetrapyrrole biosynthesis|tetrapyrrole anabolism|tetrapyrrole synthesis|tetrapyrrole formation													biological_process											owl:Class	
GO:0009311	biolink:NamedThing	oligosaccharide metabolic process	The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	got7fsn_ti	oligosaccharide metabolism|multicellular organismal oligosaccharide metabolic process										GO:0051690			biological_process											owl:Class	
GO:0010078	biolink:NamedThing	maintenance of root meristem identity	The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0102181	biolink:NamedThing	4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-11937|RHEA:59040		molecular_function											owl:Class	
GO:0046483	biolink:NamedThing	heterocycle metabolic process	The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).	got7fsn_ti	heterocycle metabolism													biological_process											owl:Class	
GO:0031380	biolink:NamedThing	nuclear RNA-directed RNA polymerase complex	A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain.	got7fsn_ti	RDRC|Rdr1 complex													cellular_component											owl:Class	
GO:0034224	biolink:NamedThing	cellular response to zinc ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.	got7fsn_ti	cellular response to zinc starvation|cellular response to zinc ion limitation													biological_process											owl:Class	
GO:0019784	biolink:NamedThing	NEDD8-specific protease activity	Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.	got7fsn_ti	deneddylase activity											Reactome:R-HSA-5690808|Reactome:R-HSA-8863723|Reactome:R-HSA-8956040|Reactome:R-HSA-8956045		molecular_function											owl:Class	
GO:0030694	biolink:NamedThing	bacterial-type flagellum basal body, rod	The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings.	got7fsn_ti	flagellar basal body, rod|flagellin-based flagellum basal body, rod													cellular_component											owl:Class	
GO:0033743	biolink:NamedThing	peptide-methionine (R)-S-oxide reductase activity	Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.	got7fsn_ti	PilB|protein-methionine-R-oxide reductase activity|SelR|methionine sulfoxide reductase activity|methionine S-oxide reductase activity|pMRsr|SelX|MsrB|pMSR|selenoprotein R|methionine S-oxide reductase (R-form oxidizing) activity|methionine sulfoxide reductase B activity|peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity										GO:0000318	Reactome:R-HSA-5676917|RHEA:24164|EC:1.8.4.12|KEGG_REACTION:R07607|MetaCyc:1.8.4.12-RXN		molecular_function											owl:Class	
GO:0036377	biolink:NamedThing	arbuscular mycorrhizal association	A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil.	got7fsn_ti	arbuscular mycorrhizal symbiosis|arbuscular mycorrhizae formation|arbuscular mycorrhizas formation						bf	2013-05-07T15:07:32Z						biological_process											owl:Class	
GO:0033413	biolink:NamedThing	UGU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UGU codon.	got7fsn_ti	TGT codon-amino acid adaptor activity|cysteine tRNA				Note that in the standard genetic code, TGT codes for cysteine.									molecular_function											owl:Class	
GO:0099556	biolink:NamedThing	trans-synaptic signaling by carbon monoxide, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0099554	biolink:NamedThing	trans-synaptic signaling by soluble gas, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0007478	biolink:NamedThing	leg disc morphogenesis	The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura.	got7fsn_ti	leg disc metamorphosis													biological_process											owl:Class	
GO:0051056	biolink:NamedThing	regulation of small GTPase mediated signal transduction	Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.	got7fsn_ti	regulation of small GTPase-mediated signal transduction													biological_process											owl:Class	
GO:0005958	biolink:NamedThing	DNA-dependent protein kinase-DNA ligase 4 complex	A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV.	got7fsn_ti											GO:0005959			cellular_component											owl:Class	
GO:0047645	biolink:NamedThing	alkan-1-ol dehydrogenase (acceptor) activity	Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor.	got7fsn_ti	alkan-1-ol:(acceptor) oxidoreductase activity|polyethylene glycol dehydrogenase activity|alkan-1-ol:acceptor oxidoreductase activity											EC:1.1.99.20|MetaCyc:ALKAN-1-OL-DEHYDROGENASE-ACCEPTOR-RXN|RHEA:14685		molecular_function											owl:Class	
GO:0046740	biolink:NamedThing	transport of virus in host, cell to cell	The transport of a virus between adjacent cells in a multicellular organism.	got7fsn_ti	spread of virus in host, cell to cell|intercellular virus transport|viral spread within host, cell to cell|spread of virus within host, cell to cell|cell to cell spread of virus within host											VZ:1018		biological_process											owl:Class	
GO:0047867	biolink:NamedThing	dimethylmalate dehydrogenase activity	Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO(2) + NADH.	got7fsn_ti	beta,beta-dimethylmalate dehydrogenase activity|(R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)											KEGG_REACTION:R01211|EC:1.1.1.84|RHEA:13321|MetaCyc:DIMETHYLMALATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0046192	biolink:NamedThing	anaerobic phenol-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.	got7fsn_ti	anaerobic phenol-containing compound biosynthesis|anaerobic phenol-containing compound anabolism|anaerobic phenol-containing compound synthesis|anaerobic phenol-containing compound formation													biological_process											owl:Class	
GO:0042215	biolink:NamedThing	anaerobic phenol-containing compound metabolic process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.	got7fsn_ti	anaerobic phenol-containing compound metabolism											UM-BBD_pathwayID:phe		biological_process											owl:Class	
GO:0045513	biolink:NamedThing	interleukin-27 binding	Binding to interleukin-27.	got7fsn_ti	IL-27 binding													molecular_function											owl:Class	
GO:0035681	biolink:NamedThing	toll-like receptor 15 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 15.	got7fsn_ti	toll-like receptor 15 signalling pathway|TLR15 signaling pathway						bf	2011-02-21T02:38:47Z						biological_process											owl:Class	
GO:0106149	biolink:NamedThing	indole-3-carbonyl nitrile 4-hydroxylase activity	Catalysis of the reaction: indole-3-carbonyl nitrile + NADPH +O2=4-hydroxyindole-3- carbonyl nitrile + NADP(+) + H20.	got7fsn_ti							hjd	2018-09-10T19:44:15Z				RHEA:57864|EC:1.14.14.165		molecular_function											owl:Class	
GO:0071612	biolink:NamedThing	IP-10 production	The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CXCL10 production|chemokine (C-C motif) ligand 10 production						mah	2010-02-05T04:43:56Z						biological_process											owl:Class	
GO:0031467	biolink:NamedThing	Cul7-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein.	got7fsn_ti	SCF7 complex|cullin-RING ligase 7|CRL7 complex|CDL7 complex													cellular_component											owl:Class	
GO:0050709	biolink:NamedThing	negative regulation of protein secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.	got7fsn_ti	downregulation of protein secretion|inhibition of protein secretion|down-regulation of protein secretion|down regulation of protein secretion													biological_process											owl:Class	
GO:0098976	biolink:NamedThing	excitatory chemical synaptic transmission	Synaptic transmission that results in an excitatory postsynaptic potential.	got7fsn_ti														biological_process											owl:Class	
GO:0034026	biolink:NamedThing	L-amino-acid alpha-ligase activity	Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid.	got7fsn_ti	YwfE|bacilysin synthetase activity|L-amino acid ligase activity|L-amino acid alpha-ligase activity											RHEA:44332|EC:6.3.2.49|MetaCyc:6.3.2.28-RXN		molecular_function											owl:Class	
GO:0038109	biolink:NamedThing	Kit signaling pathway	A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell.	got7fsn_ti	SCF signaling pathway|stem cell factor receptor signaling pathway|stem cell factor signaling pathway|Kit signalling pathway						bf	2012-03-22T10:09:48Z						biological_process											owl:Class	
GO:0090219	biolink:NamedThing	negative regulation of lipid kinase activity	Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.	got7fsn_ti							tb	2010-01-12T10:18:30Z						biological_process											owl:Class	
GO:0045833	biolink:NamedThing	negative regulation of lipid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.	got7fsn_ti	down regulation of lipid metabolic process|down-regulation of lipid metabolic process|downregulation of lipid metabolic process|negative regulation of lipid metabolism|inhibition of lipid metabolic process													biological_process											owl:Class	
GO:0009018	biolink:NamedThing	sucrose phosphorylase activity	Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate.	got7fsn_ti	disaccharide glucosyltransferase activity|sucrose glucosyltransferase activity|sucrose:phosphate alpha-D-glucosyltransferase activity											RHEA:24048|MetaCyc:SUCROSE-PHOSPHORYLASE-RXN|EC:2.4.1.7		molecular_function											owl:Class	
GO:0050103	biolink:NamedThing	dextrin dextranase activity	Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1).	got7fsn_ti	1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity|dextran dextrinase activity|dextrin 6-glucosyltransferase activity											EC:2.4.1.2|RHEA:14625|MetaCyc:DEXTRIN-DEXTRANASE-RXN		molecular_function											owl:Class	
GO:0004550	biolink:NamedThing	nucleoside diphosphate kinase activity	Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.	got7fsn_ti	nucleotide phosphate kinase activity|nucleoside diphosphate (UDP) kinase activity|uridine diphosphate kinase activity|nucleoside 5'-diphosphate kinase activity|nucleoside diphosphokinase activity|NDK activity|nucleoside 5'-diphosphate phosphotransferase activity|UDP kinase activity|nucleoside-diphosphate kinase activity|ATP:nucleoside-diphosphate phosphotransferase activity											Reactome:R-HSA-482804|Reactome:R-HSA-2162096|Reactome:R-HSA-6806877|Reactome:R-HSA-482621|EC:2.7.4.6|Reactome:R-HSA-482619|MetaCyc:NUCLEOSIDE-DIP-KIN-RXN|Reactome:R-HSA-482812		molecular_function											owl:Class	
GO:0008995	biolink:NamedThing	ribonuclease E activity	Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.	got7fsn_ti												MetaCyc:3.1.26.12-RXN		molecular_function											owl:Class	
GO:1990809	biolink:NamedThing	endoplasmic reticulum tubular network membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane.	got7fsn_ti							vw	2015-07-22T16:42:36Z						biological_process											owl:Class	
GO:0061010	biolink:NamedThing	gall bladder development	The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile.	got7fsn_ti							dph	2010-01-22T09:38:44Z						biological_process											owl:Class	
GO:0071418	biolink:NamedThing	cellular response to amine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.	got7fsn_ti							mah	2009-12-14T04:08:17Z						biological_process											owl:Class	
GO:1902621	biolink:NamedThing	actomyosin contractile ring disassembly	The disaggregation of an actomyosin contractile ring into its constituent components.	got7fsn_ti	contractile actomyosin ring disassembly|constriction ring disassembly|CAR disassembly|actomyosin ring disassembly|cytokinetic ring disassembly						mah	2014-01-15T09:27:26Z						biological_process											owl:Class	
GO:0006934	biolink:NamedThing	substrate-bound cell migration, adhesion receptor recycling	The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions.	got7fsn_ti														biological_process											owl:Class	
GO:0007603	biolink:NamedThing	phototransduction, visible light	The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.	got7fsn_ti	visual transduction|visual cascade													biological_process											owl:Class	
GO:0009584	biolink:NamedThing	detection of visible light	The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.	got7fsn_ti	perception of visible light													biological_process											owl:Class	
GO:0060661	biolink:NamedThing	submandibular salivary gland formation	The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.	got7fsn_ti							dph	2009-06-01T08:07:16Z						biological_process											owl:Class	
GO:0021575	biolink:NamedThing	hindbrain morphogenesis	The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.	got7fsn_ti	rhombencephalon morphogenesis													biological_process											owl:Class	
GO:0002035	biolink:NamedThing	brain renin-angiotensin system	The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system.	got7fsn_ti														biological_process											owl:Class	
GO:0047000	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH.	got7fsn_ti	2-keto-3-deoxy-D-gluconate dehydrogenase activity|2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase activity											KEGG_REACTION:R01543|MetaCyc:1.1.1.126-RXN|EC:1.1.1.126|RHEA:15109		molecular_function											owl:Class	
GO:0035101	biolink:NamedThing	FACT complex	An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer.	got7fsn_ti	Facilitates chromatin transcription complex	https://github.com/geneontology/go-ontology/issues/19572												cellular_component											owl:Class	
GO:0072666	biolink:NamedThing	establishment of protein localization to vacuole	The directed movement of a protein to a specific location in a vacuole.	got7fsn_ti	establishment of protein localisation to vacuole						mah	2011-02-14T02:56:29Z						biological_process											owl:Class	
GO:1990648	biolink:NamedThing	inositol-4,5,6-triphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate.	got7fsn_ti							al	2015-02-23T11:10:51Z						molecular_function											owl:Class	
GO:0009372	biolink:NamedThing	quorum sensing	The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms.	got7fsn_ti	quorum sensing system|cell-cell signaling involved in quorum sensing|detection of cell density by secreted molecule										GO:0060247|GO:0010699	Wikipedia:Quorum_sensing		biological_process											owl:Class	
GO:0086097	biolink:NamedThing	phospholipase C-activating angiotensin-activated signaling pathway	An angiotensin-mediated signaling pathway where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores.	got7fsn_ti	phospholipase C-activating angiotensin-mediated signaling pathway|PLC-activating angiotensin receptor signaling pathway|angiotensin-mediated signaling pathway via activation of phospholipase C|Gq-coupled angiotensin receptor signaling pathway|phospholipase C-activating angiotensin receptor signaling pathway						bf	2012-06-13T11:28:15Z						biological_process											owl:Class	
GO:0046504	biolink:NamedThing	glycerol ether biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.	got7fsn_ti	glycerol ether synthesis|glycerol ether anabolism|glycerol ether formation|glycerol ether biosynthesis													biological_process											owl:Class	
GO:0008455	biolink:NamedThing	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.	got7fsn_ti	UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity|alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity|uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity|GnTII activity|alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase II activity|UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase II activity											EC:2.4.1.143|Reactome:R-HSA-4793955|Reactome:R-HSA-9694656|MetaCyc:2.4.1.143-RXN|RHEA:12941|Reactome:R-HSA-975829		molecular_function											owl:Class	
GO:0000800	biolink:NamedThing	lateral element	A proteinaceous core found between sister chromatids during meiotic prophase.	got7fsn_ti	axial element				In species that have a synaptonemal complex, the lateral elements are part of this complex.  S.pombe is an example of a species that lacks a  (canonical) synaptonemal complex, but still has lateral elements.									cellular_component											owl:Class	
GO:0038019	biolink:NamedThing	Wnt receptor recycling	The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.	got7fsn_ti	Frizzled recycling						bf	2011-06-23T04:46:11Z						biological_process											owl:Class	
GO:0043260	biolink:NamedThing	laminin-11 complex	A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains.	got7fsn_ti	laminin-521 complex													cellular_component											owl:Class	
GO:0150093	biolink:NamedThing	amyloid-beta clearance by transcytosis	The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.	got7fsn_ti							bc	2018-08-16T14:33:47Z						biological_process											owl:Class	
GO:0045056	biolink:NamedThing	transcytosis	The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.	got7fsn_ti												Wikipedia:Transcytosis		biological_process											owl:Class	
GO:0043553	biolink:NamedThing	negative regulation of phosphatidylinositol 3-kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity.	got7fsn_ti	down-regulation of phosphatidylinositol 3-kinase activity|inhibition of phosphatidylinositol 3-kinase activity|down regulation of phosphatidylinositol 3-kinase activity|negative regulation of PI3K activity|downregulation of phosphatidylinositol 3-kinase activity|negative regulation of phosphoinositide 3-kinase activity													biological_process											owl:Class	
GO:0002370	biolink:NamedThing	natural killer cell cytokine production	Any process that contributes to cytokine production by a natural killer cell.	got7fsn_ti	NK cell cytokine production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0031036	biolink:NamedThing	myosin II filament assembly	The formation of a bipolar filament composed of myosin II molecules.	got7fsn_ti	myosin II polymerization													biological_process											owl:Class	
GO:0034787	biolink:NamedThing	1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity	Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1040		molecular_function											owl:Class	
GO:0000387	biolink:NamedThing	spliceosomal snRNP assembly	The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.	got7fsn_ti	spliceosomal snRNP biogenesis													biological_process											owl:Class	
GO:0010585	biolink:NamedThing	glutamine secretion	The controlled release of glutamine by a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0010226	biolink:NamedThing	response to lithium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0060829	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis.	got7fsn_ti	negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern|negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation|negative regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|negative regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern						dph	2009-08-11T01:58:33Z						biological_process											owl:Class	
GO:0052682	biolink:NamedThing	epi-cedrol synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate.	got7fsn_ti	(2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming) activity|epicedrol synthase activity|8-epicedrol synthase activity											EC:4.2.3.39|KEGG_REACTION:R09140|RHEA:26115|MetaCyc:RXN-10004		molecular_function											owl:Class	
GO:0003112	biolink:NamedThing	positive regulation of heart rate by neuronal epinephrine	The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction.	got7fsn_ti	positive regulation of heart rate by neuronal adrenaline													biological_process											owl:Class	
GO:0003065	biolink:NamedThing	positive regulation of heart rate by epinephrine	The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.	got7fsn_ti	adrenaline cardiac chronotropy|positive regulation of heart contraction rate by epinephrine|adrenaline regulation of the rate of heart muscle contraction|positive regulation of heart rate by adrenaline|epinephrine cardiac chronotropy													biological_process											owl:Class	
GO:0033219	biolink:NamedThing	urea binding	Binding to urea, a water-soluble carboxamide with the structure H2N-CO-NH2.	got7fsn_ti														molecular_function											owl:Class	
GO:0047467	biolink:NamedThing	4-hydroxyphenylacetaldehyde-oxime isomerase activity	Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime.	got7fsn_ti														molecular_function											owl:Class	
GO:0034227	biolink:NamedThing	tRNA thio-modification	The addition a sulfur atom to a nucleotide in a tRNA molecule.	got7fsn_ti	tRNA sulfurtransferase activity|tRNA thiolation											MetaCyc:TRNA-S-TRANSFERASE-RXN|EC:2.8.1.4		biological_process											owl:Class	
GO:0046875	biolink:NamedThing	ephrin receptor binding	Binding to an ephrin receptor.	got7fsn_ti	transmembrane ephrin|Eph receptor binding|ephrin|GPI-linked ephrin													molecular_function											owl:Class	
GO:0071819	biolink:NamedThing	DUBm complex	A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.	got7fsn_ti	deubiquitinating module|deubiquitination module|SAGA DUBm complex						mah	2010-09-07T11:19:28Z						cellular_component											owl:Class	
GO:0015265	biolink:NamedThing	urea channel activity	Enables the facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti												Reactome:R-HSA-507873|Reactome:R-HSA-507875		molecular_function											owl:Class	
GO:0102501	biolink:NamedThing	D-fructuronate reductase activity	Catalysis of the reaction: D-mannonate + NADP = NADPH + H+ + D-fructuronate.	got7fsn_ti												MetaCyc:RXN-14368		molecular_function											owl:Class	
GO:0018679	biolink:NamedThing	dibenzothiophene-5,5-dioxide monooxygenase activity	Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate.	got7fsn_ti												EC:1.14.14.-|MetaCyc:RXN-623|UM-BBD_reactionID:r0235		molecular_function											owl:Class	
GO:0032304	biolink:NamedThing	negative regulation of icosanoid secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.	got7fsn_ti	inhibition of icosanoid secretion|down-regulation of icosanoid secretion|negative regulation of eicosanoid secretion|downregulation of icosanoid secretion|down regulation of icosanoid secretion													biological_process											owl:Class	
GO:2000192	biolink:NamedThing	negative regulation of fatty acid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.	got7fsn_ti							rl	2010-10-18T10:37:15Z						biological_process											owl:Class	
GO:0140381	biolink:NamedThing	4-hydroxytryptamine 4-phosphate methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) <=> 2 S-adenosyl-L-homocysteine + psilocybin.	got7fsn_ti	norbaeocystin methyltransferase|psilocybin synthase						pg	2019-11-20T10:16:28Z				RHEA:55568|EC:2.1.1.345		molecular_function											owl:Class	
GO:0007517	biolink:NamedThing	muscle organ development	The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.	got7fsn_ti														biological_process											owl:Class	
GO:0030995	biolink:NamedThing	cell septum edging catabolic process	The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.	got7fsn_ti	hydrolysis of edging of cell septum|cell septum edging hydrolysis|hydrolysis of cell septum edging|septum edging hydrolysis													biological_process											owl:Class	
GO:0071999	biolink:NamedThing	extracellular polysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures.	got7fsn_ti	extracellular polysaccharide breakdown|extracellular polysaccharide catabolism|extracellular polysaccharide degradation						mah	2010-10-25T05:11:25Z						biological_process											owl:Class	
GO:0018516	biolink:NamedThing	2,4-dichlorobenzoyl-CoA reductase activity	Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH.	got7fsn_ti	4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)											RHEA:23076|EC:1.21.1.2|UM-BBD_reactionID:r0138|MetaCyc:1.3.1.63-RXN|KEGG_REACTION:R05276		molecular_function											owl:Class	
GO:0021559	biolink:NamedThing	trigeminal nerve development	The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	got7fsn_ti	cranial nerve 5 development|CN V development|cranial nerve V development													biological_process											owl:Class	
GO:0050910	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of sound	The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.	got7fsn_ti	detection of sound|perception of sound, sensory detection of mechanical stimulus|perception of sound, sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus during perception of sound|sensory transduction of sound|hearing, sensory transduction of sound|sensory transduction of mechanical stimulus during perception of sound|perception of sound, detection of mechanical stimulus										GO:0055128|GO:0009592			biological_process											owl:Class	
GO:0050334	biolink:NamedThing	thiaminase activity	Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+).	got7fsn_ti	thiaminase II activity											RHEA:17509|KEGG_REACTION:R02133|MetaCyc:THIAMINASE-RXN|EC:3.5.99.2		molecular_function											owl:Class	
GO:0047272	biolink:NamedThing	phosphopolyprenol glucosyltransferase activity	Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP.	got7fsn_ti	UDP-glucose:phosphopolyprenol D-glucosyltransferase activity|UDPglucose:polyprenol monophosphate glucosyltransferase activity|UDPglucose:phosphopolyprenol D-glucosyltransferase activity|uridine diphosphoglucose-polyprenol monophosphate glucosyltransferase activity											EC:2.4.1.78|MetaCyc:2.4.1.78-RXN		molecular_function											owl:Class	
GO:0019358	biolink:NamedThing	nicotinate nucleotide salvage	The generation of nicotinate nucleotide without de novo synthesis.	got7fsn_ti	nicotinate nucleotide biosynthesis, salvage pathway|nicotinate nucleotide biosynthetic process, salvage pathway											MetaCyc:PYRIDNUCSAL-PWY|MetaCyc:PWY-5381		biological_process											owl:Class	
GO:0070489	biolink:NamedThing	T cell aggregation	The adhesion of one T cell to one or more other T cells via adhesion molecules.	got7fsn_ti	T-lymphocyte aggregation|T lymphocyte aggregation|T-cell aggregation													biological_process											owl:Class	
GO:0071593	biolink:NamedThing	lymphocyte aggregation	The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules.	got7fsn_ti							mah	2010-01-29T01:37:30Z						biological_process											owl:Class	
GO:0072247	biolink:NamedThing	metanephric glomerular parietal epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.	got7fsn_ti	metanephric Bowman's capsule cell fate commitment						mah	2010-03-19T03:42:27Z						biological_process											owl:Class	
GO:0072315	biolink:NamedThing	metanephric glomerular epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.	got7fsn_ti							mah	2010-04-09T07:03:50Z						biological_process											owl:Class	
GO:0071410	biolink:NamedThing	cellular response to cyclopentenone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.	got7fsn_ti							mah	2009-12-14T03:09:49Z						biological_process											owl:Class	
GO:2000821	biolink:NamedThing	regulation of grooming behavior	Any process that modulates the frequency, rate or extent of grooming behavior.	got7fsn_ti	regulation of grooming behaviour						rl	2011-07-14T04:48:12Z						biological_process											owl:Class	
GO:0090706	biolink:NamedThing	specification of plant organ position	The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ.	got7fsn_ti							tb	2016-10-05T12:33:21Z						biological_process											owl:Class	
GO:0090435	biolink:NamedThing	protein localization to nuclear envelope	A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.	got7fsn_ti	protein localization in nuclear envelope						tb	2012-07-30T01:50:41Z						biological_process											owl:Class	
GO:0120048	biolink:NamedThing	U6 snRNA (adenine-(43)-N(6))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA.	got7fsn_ti							krc	2017-06-02T20:37:40Z						molecular_function											owl:Class	
GO:0106346	biolink:NamedThing	snRNA methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.	got7fsn_ti							hjd	2020-12-18T15:06:44Z						molecular_function											owl:Class	
GO:0106342	biolink:NamedThing	omega-hydroxyceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide.	got7fsn_ti							hjd	2020-11-17T17:15:25Z						biological_process											owl:Class	
GO:0046513	biolink:NamedThing	ceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.	got7fsn_ti	ceramide biosynthesis|ceramide formation|ceramide anabolism|ceramide synthesis													biological_process											owl:Class	
GO:0047323	biolink:NamedThing	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity	Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.	got7fsn_ti	[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity|branched-chain 2-oxo acid dehydrogenase kinase activity|3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity|STK2|branched-chain alpha-ketoacid dehydrogenase kinase activity|BCK|ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity|BCODH kinase activity|branched-chain keto acid dehydrogenase kinase activity|branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity|BCKD kinase activity											RHEA:17301|MetaCyc:2.7.11.4-RXN|Reactome:R-HSA-5693148|EC:2.7.11.4		molecular_function											owl:Class	
GO:0034546	biolink:NamedThing	2,4-dichloroaniline reductive dehalogenase activity	Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl.	got7fsn_ti												EC:1.97.1.-|UM-BBD_reactionID:r0819		molecular_function											owl:Class	
GO:0106341	biolink:NamedThing	omega-hydroxyceramide transacylase activity	Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine.	got7fsn_ti							hjd	2020-11-17T17:12:43Z				RHEA:55264		molecular_function											owl:Class	
GO:0016363	biolink:NamedThing	nuclear matrix	The dense fibrillar network lying on the inner side of the nuclear membrane.	got7fsn_ti	nucleoskeleton											Wikipedia:Nuclear_matrix		cellular_component											owl:Class	
GO:0060836	biolink:NamedThing	lymphatic endothelial cell differentiation	The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.	got7fsn_ti							dph	2009-08-11T03:45:20Z						biological_process											owl:Class	
GO:0045446	biolink:NamedThing	endothelial cell differentiation	The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.	got7fsn_ti														biological_process											owl:Class	
GO:0003880	biolink:NamedThing	protein C-terminal carboxyl O-methyltransferase activity	Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.	got7fsn_ti	C-terminal protein carboxyl methyltransferase activity													molecular_function											owl:Class	
GO:0072487	biolink:NamedThing	MSL complex	A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residue at position 16. In human, it contains the catalytic subunit MOF, and MSL1, MSL2 and MSL3.	got7fsn_ti							mah	2010-12-10T10:15:11Z						cellular_component											owl:Class	
GO:0009307	biolink:NamedThing	DNA restriction-modification system	A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.	got7fsn_ti	DNA restriction													biological_process											owl:Class	
GO:0031252	biolink:NamedThing	cell leading edge	The area of a motile cell closest to the direction of movement.	got7fsn_ti	leading edge of cell|front of cell													cellular_component											owl:Class	
GO:0009609	biolink:NamedThing	response to symbiotic bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism.	got7fsn_ti	response to symbiotic bacteria													biological_process											owl:Class	
GO:0033095	biolink:NamedThing	aleurone grain	A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes.	got7fsn_ti	aleurone body													cellular_component											owl:Class	
GO:0046316	biolink:NamedThing	gluconokinase activity	Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H(+).	got7fsn_ti	ATP:D-gluconate 6-phosphotransferase activity|gluconate kinase activity|gluconokinase (phosphorylating)											MetaCyc:GLUCONOKIN-RXN|EC:2.7.1.12|RHEA:19433|KEGG_REACTION:R01737		molecular_function											owl:Class	
GO:0051265	biolink:NamedThing	diolein transacylation activity	Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.	got7fsn_ti	dioleoylglycerol transacylase activity|acyl-CoA-independent diolein transacylation|DOG transacylation|dioleoylglycerol O-acyltransferase activity													molecular_function											owl:Class	
GO:0016411	biolink:NamedThing	acylglycerol O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.	got7fsn_ti												Reactome:R-HSA-1482647|Reactome:R-HSA-1482654		molecular_function											owl:Class	
GO:0061560	biolink:NamedThing	cranial ganglion formation	The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti	cranial ganglia formation						dph	2013-07-10T09:07:27Z						biological_process											owl:Class	
GO:0061554	biolink:NamedThing	ganglion formation	The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti	ganglia formation						dph	2013-07-10T08:51:50Z						biological_process											owl:Class	
GO:0035886	biolink:NamedThing	vascular associated smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.	got7fsn_ti	VSMC differentiation|vascular associated smooth muscle cell differentiation|vascular smooth muscle cell differentiation						bf	2011-06-08T11:23:52Z						biological_process											owl:Class	
GO:0060656	biolink:NamedThing	regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling	Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell.	got7fsn_ti	regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signalling						dph	2009-05-29T09:34:31Z						biological_process											owl:Class	
GO:0060762	biolink:NamedThing	regulation of branching involved in mammary gland duct morphogenesis	Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.	got7fsn_ti							dph	2009-06-22T05:20:33Z						biological_process											owl:Class	
GO:0004529	biolink:NamedThing	exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0060210	biolink:NamedThing	metestrus	The estrous cycle phase in which there is subsiding follicular function.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0030575	biolink:NamedThing	nuclear body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.	got7fsn_ti	nuclear body organisation|nuclear body organization and biogenesis													biological_process											owl:Class	
GO:0034998	biolink:NamedThing	oligosaccharyltransferase I complex	An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes.	got7fsn_ti	OSTCI													cellular_component											owl:Class	
GO:0008250	biolink:NamedThing	oligosaccharyltransferase complex	A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected.	got7fsn_ti	OST complex|oligosaccharyl transferase complex													cellular_component											owl:Class	
GO:0051362	biolink:NamedThing	peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine	The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species.	got7fsn_ti	biosynthesis of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine				See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.							RESID:AA0382		biological_process											owl:Class	
GO:0051268	biolink:NamedThing	alpha-keto amide reductase activity	Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.	got7fsn_ti														molecular_function											owl:Class	
GO:0140456	biolink:NamedThing	initial meiotic spindle pole body separation	The release of duplicated meiotic spindle pole bodies (SPBs).	got7fsn_ti	initial spindle pole body separation involved in meiosis I|meiotic spindle pole body duplication	https://github.com/geneontology/go-ontology/issues/17971					pg	2020-04-22T19:07:22Z						biological_process											owl:Class	
GO:0050585	biolink:NamedThing	4-hydroxymandelate synthase activity	Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2.	got7fsn_ti	4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)|4-hydroxyphenylpyruvate dioxygenase II activity											EC:1.13.11.46|RHEA:21376|MetaCyc:1.13.11.46-RXN		molecular_function											owl:Class	
GO:0035997	biolink:NamedThing	rhabdomere microvillus membrane	The portion of the plasma membrane surrounding a microvillus of a rhabdomere.	got7fsn_ti							bf	2011-09-01T02:24:20Z						cellular_component											owl:Class	
GO:0031528	biolink:NamedThing	microvillus membrane	The portion of the plasma membrane surrounding a microvillus.	got7fsn_ti														cellular_component											owl:Class	
GO:0071568	biolink:NamedThing	UFM1 transferase activity	Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.	got7fsn_ti							mah	2010-01-20T04:10:11Z						molecular_function											owl:Class	
GO:0003985	biolink:NamedThing	acetyl-CoA C-acetyltransferase activity	Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.	got7fsn_ti	acetyl coenzyme A thiolase activity|2-methylacetoacetyl-CoA thiolase|beta-acetoacetyl coenzyme A thiolase activity|acetyl-CoA:N-acetyltransferase activity|acetoacetyl-CoA thiolase activity|thiolase II|acetyl-CoA:acetyl-CoA C-acetyltransferase activity|3-oxothiolase activity|acetyl-CoA acetyltransferase activity											MetaCyc:ACETYL-COA-ACETYLTRANSFER-RXN|EC:2.3.1.9|UM-BBD_enzymeID:e0144|Reactome:R-HSA-70844|Reactome:R-HSA-74181|Reactome:R-HSA-8848215|RHEA:21036|Reactome:R-HSA-73916		molecular_function											owl:Class	
GO:0016453	biolink:NamedThing	C-acetyltransferase activity	Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0071007	biolink:NamedThing	U2-type catalytic step 2 spliceosome	A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.	got7fsn_ti	mammalian U2-type spliceosomal complex C|mammalian U2-type spliceosomal complex C1|GT-AG catalytic step 2 spliceosome|major catalytic step 2 spliceosome|yeast U2-type spliceosomal complex A2-2						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0038035	biolink:NamedThing	G protein-coupled receptor signaling in absence of ligand	A series of molecular signals beginning with a consequence of a G protein-coupled receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex, where the G protein-coupled receptor is not bound to an agonist.	got7fsn_ti	G-protein coupled receptor signalling in absence of ligand|basal G-protein coupled receptor signaling|G-protein coupled receptor signaling in absence of agonist|G-protein coupled receptor signaling in absence of ligand				This term is intended for use by G protein-coupled receptors which signal at a low-level in the absence of agonist binding.		bf	2011-10-26T02:31:37Z						biological_process											owl:Class	
GO:0034616	biolink:NamedThing	response to laminar fluid shear stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.	got7fsn_ti														biological_process											owl:Class	
GO:1900734	biolink:NamedThing	positive regulation of polyketide biosynthetic process	Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process.	got7fsn_ti	activation of polyketide anabolism|positive regulation of polyketide anabolism|activation of polyketide biosynthetic process|positive regulation of polyketide biosynthesis|up regulation of polyketide formation|up-regulation of polyketide biosynthesis|up-regulation of polyketide anabolism|positive regulation of polyketide formation|up regulation of polyketide anabolism|up-regulation of polyketide formation|up regulation of polyketide biosynthesis|activation of polyketide biosynthesis|up regulation of polyketide synthesis|up-regulation of polyketide biosynthetic process|upregulation of polyketide formation|up-regulation of polyketide synthesis|positive regulation of polyketide synthesis|upregulation of polyketide biosynthetic process|activation of polyketide synthesis|activation of polyketide formation|upregulation of polyketide biosynthesis|up regulation of polyketide biosynthetic process|upregulation of polyketide anabolism|upregulation of polyketide synthesis						di	2012-05-26T01:30:10Z						biological_process											owl:Class	
GO:0031328	biolink:NamedThing	positive regulation of cellular biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.	got7fsn_ti	activation of cellular biosynthetic process|positive regulation of cellular biosynthesis|positive regulation of cellular synthesis|stimulation of cellular biosynthetic process|up regulation of cellular biosynthetic process|up-regulation of cellular biosynthetic process|positive regulation of cellular formation|upregulation of cellular biosynthetic process|positive regulation of cellular anabolism													biological_process											owl:Class	
GO:0060077	biolink:NamedThing	inhibitory synapse	A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.	got7fsn_ti												Wikipedia:Inhibitory_postsynaptic_potential		cellular_component											owl:Class	
GO:0071044	biolink:NamedThing	histone mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).	got7fsn_ti							krc	2009-07-30T09:48:10Z						biological_process											owl:Class	
GO:0008334	biolink:NamedThing	histone mRNA metabolic process	The chemical reactions and pathways involving an mRNA encoding a histone.	got7fsn_ti	stem-loop-containing histone mRNA 3'-end processing|histone mRNA metabolism				In higher Eukaryotes, histone mRNAs (stem-loop containing) are non-polyadenylated and thus have a different form of 3'-end regulation to other mRNAs. In lower Eukaryotes, the 3'-ends of histone mRNAs are polyadenylated.									biological_process											owl:Class	
GO:0018557	biolink:NamedThing	1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0422		molecular_function											owl:Class	
GO:0019117	biolink:NamedThing	dihydroxyfluorene dioxygenase activity	Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid.	got7fsn_ti												EC:1.13.11.-		molecular_function											owl:Class	
GO:0021971	biolink:NamedThing	corticospinal neuron axon guidance through the medullary pyramid	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues.	got7fsn_ti	corticospinal neuron axon pathfinding through the medullary pyramid													biological_process											owl:Class	
GO:0047159	biolink:NamedThing	1-alkenylglycerophosphocholine O-acyltransferase activity	Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA.	got7fsn_ti	acyl-CoA:1-alkenylglycerophosphocholine O-acyltransferase activity											MetaCyc:2.3.1.104-RXN|EC:2.3.1.25|RHEA:10344		molecular_function											owl:Class	
GO:0050894	biolink:NamedThing	determination of affect	Any process in which an emotional response is associated with a particular sensory stimulation.	got7fsn_ti														biological_process											owl:Class	
GO:0016210	biolink:NamedThing	naringenin-chalcone synthase activity	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.	got7fsn_ti	malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)|DOCS											EC:2.3.1.74|RHEA:11128|MetaCyc:NARINGENIN-CHALCONE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0090014	biolink:NamedThing	leaflet formation	The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf.	got7fsn_ti							tb	2009-07-29T11:05:37Z						biological_process											owl:Class	
GO:0060650	biolink:NamedThing	epithelial cell proliferation involved in mammary gland bud elongation	The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud.	got7fsn_ti							dph	2009-05-29T08:54:54Z						biological_process											owl:Class	
GO:0003961	biolink:NamedThing	O-acetylhomoserine aminocarboxypropyltransferase activity	Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.	got7fsn_ti	L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine|L-methionine anabolism, direct, from O-acetyl-L-homoserine|methionine biosynthetic process, direct, from O-acetyl-L-homoserine|L-methionine formation, direct, from O-acetyl-L-homoserine|O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase activity|O-acetyl-L-homoserine sulfhydrolase activity|O-acetylhomoserine sulfhydrolase activity|O-acetylhomoserine (thiol)-lyase activity|OAH sulfhydrylase activity|L-methionine synthesis, direct, from O-acetyl-L-homoserine|O-acetyl-L-homoserine acetate-lyase (adding methanethiol) activity				Note that this function was formerly EC:4.2.99.10.						GO:0019282	RHEA:10048|MetaCyc:O-ACETYLHOMOSERINE-THIOL-LYASE-RXN|EC:2.5.1.49		molecular_function											owl:Class	
GO:0034205	biolink:NamedThing	amyloid-beta formation	The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).	got7fsn_ti	beta-amyloid polypeptide formation from APP|beta-amyloid formation|beta-amyloid polypeptide formation from amyloid precursor protein				Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because amyloid-beta can only be formed by the proteolysis of a larger molecule (see term definition). The word 'formation' is therefore used in place of biosynthesis. Also, note that this term refers to the production of the amyloid-beta polypeptide from the amyloid precursor protein (APP), and should be used to annotate e.g. secretases that cleave APP to form amyloid-beta. To annotate gene products involved in the formation of amyloid fibrils, please consider 'amyloid fibril formation' (GO:1990000).									biological_process											owl:Class	
GO:0050435	biolink:NamedThing	amyloid-beta metabolic process	The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).	got7fsn_ti	beta-amyloid metabolic process|beta-amyloid metabolism|amyloid-beta metabolism													biological_process											owl:Class	
GO:0071596	biolink:NamedThing	ubiquitin-dependent protein catabolic process via the N-end rule pathway	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation.	got7fsn_ti	ubiquitin-dependent protein degradation via the N-end rule pathway|ubiquitin-dependent protein catabolism via the N-end rule pathway|ubiquitin-dependent protein breakdown via the N-end rule pathway						mah	2010-01-29T03:01:09Z						biological_process											owl:Class	
GO:0051019	biolink:NamedThing	mitogen-activated protein kinase binding	Binding to a mitogen-activated protein kinase.	got7fsn_ti	MAPK binding|MAP kinase binding|MAP-kinase anchoring activity													molecular_function											owl:Class	
GO:0120164	biolink:NamedThing	conidium germination	The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination.	got7fsn_ti							krc	2018-05-17T17:03:32Z						biological_process											owl:Class	
GO:0060613	biolink:NamedThing	fat pad development	The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.	got7fsn_ti							dph	2009-05-15T12:42:08Z						biological_process											owl:Class	
GO:0004813	biolink:NamedThing	alanine-tRNA ligase activity	Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).	got7fsn_ti	L-alanine:tRNAAla ligase (AMP-forming)|alanine-transfer RNA ligase activity|alanyl-transfer RNA synthetase activity|alanine translase activity|Ala-tRNA synthetase activity|alanyl-transfer ribonucleate synthetase activity|alanyl-tRNA synthetase activity|alanyl-transfer ribonucleic acid synthetase activity|AlaRS|alanine tRNA synthetase activity|alanine transfer RNA synthetase activity|alanyl-transfer ribonucleate synthase activity											RHEA:12540|EC:6.1.1.7|MetaCyc:ALANINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379864|Reactome:R-HSA-380177		molecular_function											owl:Class	
GO:0102253	biolink:NamedThing	neoagarobiose 1,3-alpha-3,6-anhydro-L-galactosidase activity	Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside.	got7fsn_ti												EC:3.2.1.159|MetaCyc:RXN-12426		molecular_function											owl:Class	
GO:0030249	biolink:NamedThing	guanylate cyclase regulator activity	Modulates the activity of guanylate cyclase.	got7fsn_ti														molecular_function											owl:Class	
GO:0007619	biolink:NamedThing	courtship behavior	The behavior of an organism for the purpose of attracting sexual partners.	got7fsn_ti	courtship behaviour													biological_process											owl:Class	
GO:0050583	biolink:NamedThing	hydrogen dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP+ + H2 = NADPH + H+.	got7fsn_ti	NADP-reducing hydrogenase activity|NADP-linked hydrogenase activity|hydrogen:NADP+ oxidoreductase activity											EC:1.12.1.3|RHEA:18637|MetaCyc:1.12.1.3-RXN		molecular_function											owl:Class	
GO:0016696	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.	got7fsn_ti												EC:1.12.1.-		molecular_function											owl:Class	
GO:0043042	biolink:NamedThing	amino acid adenylylation by nonribosomal peptide synthase	Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor.	got7fsn_ti	amino acid adenylation by nonribosomal peptide synthase|amino acid adenylation by NRPS													biological_process											owl:Class	
GO:0050051	biolink:NamedThing	leukotriene-B4 20-monooxygenase activity	Catalysis of the reaction: leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H+ + H2O + oxidized [NADPH-hemoprotein reductase].	got7fsn_ti	LTB4 omega-hydroxylase activity|LTB(4) 20-hydroxylase activity|LTB(4) omega-hydroxylase activity|leukotriene-B4 omega-hydroxylase activity|leukotriene-B4 20-hydroxylase activity|LTB4 20-hydroxylase activity											MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN|RHEA:22176|Reactome:R-HSA-211873|EC:1.14.14.94		molecular_function											owl:Class	
GO:0001890	biolink:NamedThing	placenta development	The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	got7fsn_ti	placentation|placental development													biological_process											owl:Class	
GO:0019602	biolink:NamedThing	toluene oxidation via 3-hydroxytoluene	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol).	got7fsn_ti												MetaCyc:TOLUENE-DEG-3-OH-PWY		biological_process											owl:Class	
GO:0009384	biolink:NamedThing	N-acylmannosamine kinase activity	Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.	got7fsn_ti	acylmannosamine kinase activity|acetylmannosamine kinase activity|ATP:N-acetylmannosamine 6-phosphotransferase activity|acetylamidodeoxymannokinase activity|acylmannosamine kinase (phosphorylating)|ATP:N-acyl-D-mannosamine 6-phosphotransferase activity|N-acetylmannosamine kinase activity|N-acyl-D-mannosamine kinase activity|acylaminodeoxymannokinase activity											MetaCyc:N-ACYLMANNOSAMINE-KINASE-RXN|EC:2.7.1.60|Reactome:R-HSA-4085028|Reactome:R-HSA-4088322|RHEA:23832		molecular_function											owl:Class	
GO:0020010	biolink:NamedThing	conoid	A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules.	got7fsn_ti														cellular_component											owl:Class	
GO:0048185	biolink:NamedThing	activin binding	Binding to activin, a dimer of inhibin-beta subunits.	got7fsn_ti														molecular_function											owl:Class	
GO:0006566	biolink:NamedThing	threonine metabolic process	The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.	got7fsn_ti	methionine and threonine metabolic process|threonine metabolism|methionine and threonine metabolism											UM-BBD_pathwayID:met		biological_process											owl:Class	
GO:0010490	biolink:NamedThing	UDP-4-keto-rhamnose-4-keto-reductase activity	Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+.	got7fsn_ti														molecular_function											owl:Class	
GO:0021702	biolink:NamedThing	cerebellar Purkinje cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.	got7fsn_ti														biological_process											owl:Class	
GO:0039522	biolink:NamedThing	suppression by virus of host mRNA export from nucleus	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism.	got7fsn_ti	inhibition by virus of host mRNA nuclear export|negative regulation by virus of host mRNA nuclear export|suppression of host mRNA nuclear export by virus|inhibition of host mRNA nuclear export by virus						bf	2011-06-22T04:34:14Z				VZ:902		biological_process											owl:Class	
GO:0050190	biolink:NamedThing	phosphoglucokinase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+).	got7fsn_ti	ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase activity|phosphoglucokinase (phosphorylating)|ATP:D-glucose-1-phosphate 6-phosphotransferase activity|glucose-phosphate kinase activity											EC:2.7.1.10|KEGG_REACTION:R00949|RHEA:13377|MetaCyc:PHOSPHOGLUCOKINASE-RXN		molecular_function											owl:Class	
GO:0060216	biolink:NamedThing	definitive hemopoiesis	A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.	got7fsn_ti	definitive hematopoiesis|definitive haemopoiesis|definitive haematopoiesis													biological_process											owl:Class	
GO:0102213	biolink:NamedThing	in-chain hydroxy fatty acyl-CoA synthetase activity	Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA.	got7fsn_ti												MetaCyc:RXN-12184		molecular_function											owl:Class	
GO:0103107	biolink:NamedThing	castasterone 23-O-glucosyltransferase activity	Catalysis of the reaction: castasterone + UDP-alpha-D-glucose <=> castasterone-23-O-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXNQT-4398		molecular_function											owl:Class	
GO:0036221	biolink:NamedThing	UTP diphosphatase activity	Catalysis of the reaction: UTP + H2O = UMP + diphosphate.	got7fsn_ti	uridine triphosphate pyrophosphohydrolase activity						bf	2012-05-08T01:47:59Z				KEGG_REACTION:R00662|RHEA:29395		molecular_function											owl:Class	
GO:0060802	biolink:NamedThing	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification	Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.	got7fsn_ti	epiblast cell-extraembryonic ectoderm cell signalling involved in anterior/posterior axis specification						dph	2009-08-06T01:36:13Z						biological_process											owl:Class	
GO:0008841	biolink:NamedThing	dihydrofolate synthase activity	Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate.	got7fsn_ti	DHFS activity|H(2)-folate synthetase activity|dihydropteroate:L-glutamate ligase (ADP-forming) activity|FHFS/FPGS activity|dihydrofolate synthetase-folylpolyglutamate synthetase activity|7,8-dihydropteroate:L-glutamate ligase (ADP) activity|FHFS activity|H2-folate synthetase activity|7,8-dihydropteroate:L-glutamate ligase (ADP-forming)|folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase activity|dihydrofolate synthetase activity|7,8-dihydrofolate synthetase activity											RHEA:23584|MetaCyc:DIHYDROFOLATESYNTH-RXN|EC:6.3.2.12		molecular_function											owl:Class	
GO:0071774	biolink:NamedThing	response to fibroblast growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus.	got7fsn_ti	response to fibroblast growth factor stimulus|response to FGF stimulus						mah	2010-08-31T11:06:32Z						biological_process											owl:Class	
GO:0097260	biolink:NamedThing	eoxin A4 synthase activity	Catalysis of the reaction: leukotriene A4 = eoxin A4.	got7fsn_ti							pr	2012-03-08T02:57:23Z				Reactome:R-HSA-2162019		molecular_function											owl:Class	
GO:0140058	biolink:NamedThing	neuron projection arborization	The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.	got7fsn_ti	neurite branching|branching morphogenesis of a neurite|neuron projection branching|neurite arborization|branching morphogenesis of a neuron projection						pg	2017-07-12T12:25:31Z						biological_process											owl:Class	
GO:0045433	biolink:NamedThing	male courtship behavior, veined wing generated song production	The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.	got7fsn_ti	male courtship behavior, song production|male courtship behaviour, song production|male courtship behaviour, veined wing generated song production													biological_process											owl:Class	
GO:0008049	biolink:NamedThing	male courtship behavior	The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	male courtship behaviour										GO:0016542			biological_process											owl:Class	
GO:0047436	biolink:NamedThing	arylmalonate decarboxylase activity	Catalysis of the reaction: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO(2).	got7fsn_ti	2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming)|AMDase activity|AMDASE|2-aryl-2-methylmalonate carboxy-lyase activity											KEGG_REACTION:R05173|EC:4.1.1.76|RHEA:20513|MetaCyc:4.1.1.76-RXN		molecular_function											owl:Class	
GO:0033580	biolink:NamedThing	protein galactosylation at cell surface	The addition of a galactose unit to a protein amino acid at the surface of a cell.	got7fsn_ti	protein amino acid galactosylation at cell surface													biological_process											owl:Class	
GO:0042125	biolink:NamedThing	protein galactosylation	The addition of a galactose molecule to a protein amino acid.	got7fsn_ti	protein amino acid galactosylation													biological_process											owl:Class	
GO:0003043	biolink:NamedThing	vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure	A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.	got7fsn_ti	vasoconstriction of artery during aortic body chemoreceptor response to lowering of systemic arterial blood pressure													biological_process											owl:Class	
GO:0002012	biolink:NamedThing	vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure	A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.	got7fsn_ti														biological_process											owl:Class	
GO:0032630	biolink:NamedThing	interleukin-26 production	The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-26 anabolism|interleukin-26 biosynthesis|IL-26 production|AK155 secretion|interleukin-26 biosynthetic process|interleukin-26 synthesis|interleukin-26 secretion|interleukin-26 formation										GO:0045526|GO:0072624			biological_process											owl:Class	
GO:0120298	biolink:NamedThing	peptide noradrenalinyltransferase activity	Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20685					krc	2021-01-19T03:20:26Z				RHEA:66560		molecular_function											owl:Class	
GO:0033572	biolink:NamedThing	transferrin transport	The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	melanotransferrin transport													biological_process											owl:Class	
GO:0055058	biolink:NamedThing	symmetric neuroblast division	The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells.	got7fsn_ti														biological_process											owl:Class	
GO:0055057	biolink:NamedThing	neuroblast division	The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron.	got7fsn_ti	neuroblast cell division													biological_process											owl:Class	
GO:0008010	biolink:NamedThing	structural constituent of chitin-based larval cuticle	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster.	got7fsn_ti	structural constituent of larval cuticle													molecular_function											owl:Class	
GO:0005214	biolink:NamedThing	structural constituent of chitin-based cuticle	The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster.	got7fsn_ti														molecular_function											owl:Class	
GO:0036066	biolink:NamedThing	protein O-linked fucosylation	The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage.	got7fsn_ti							bf	2011-12-15T11:17:20Z						biological_process											owl:Class	
GO:0036065	biolink:NamedThing	fucosylation	The covalent attachment of a fucosyl group to an acceptor molecule.	got7fsn_ti							bf	2011-12-15T11:16:19Z						biological_process											owl:Class	
GO:0043991	biolink:NamedThing	histone H2B-S14 phosphorylation	The modification of histone H2B by the addition of an phosphate group to a serine residue at position 14 of the histone.	got7fsn_ti	histone H2BS14 phosphorylation|histone H2B phosphorylation at S14													biological_process											owl:Class	
GO:0044360	biolink:NamedThing	modulation of voltage-gated potassium channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.	got7fsn_ti							jl	2011-10-27T02:09:28Z						biological_process											owl:Class	
GO:0052855	biolink:NamedThing	ADP-dependent NAD(P)H-hydrate dehydratase activity	Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H(+) + NADH + phosphate.	got7fsn_ti	(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ADP-hydrolysing; NADH-forming)|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing)|ADP-dependent H(4)NAD(P)OH dehydratase activity|reduced nicotinamide adenine dinucleotide hydrate dehydratase activity|ADP-dependent H4NAD(P)OH dehydratase activity											EC:4.2.1.136		molecular_function											owl:Class	
GO:0047016	biolink:NamedThing	cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity	Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.	got7fsn_ti	3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity|cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity|3beta-hydroxy-delta5-C27-steroid oxidoreductase|cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity											RHEA:11896|EC:1.1.1.181|MetaCyc:1.1.1.181-RXN		molecular_function											owl:Class	
GO:0035668	biolink:NamedThing	TRAM-dependent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	got7fsn_ti	TRAM-dependent toll-like receptor signalling pathway|TRAM-dependent TLR signaling pathway						bf	2011-02-01T02:39:34Z						biological_process											owl:Class	
GO:0032189	biolink:NamedThing	maintenance of actomyosin contractile ring localization	Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere.	got7fsn_ti	cytokinetic ring anchoring|maintenance of contractile ring localization involved in cell cycle cytokinesis|maintenance of contractile ring localisation involved in cell cycle cytokinesis|maintenance of contractile ring localization involved in cytokinesis during cell cycle													biological_process											owl:Class	
GO:0002935	biolink:NamedThing	tRNA (adenine-C2-)-methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA.	got7fsn_ti							hjd	2012-09-04T14:39:56Z						molecular_function											owl:Class	
GO:0019266	biolink:NamedThing	asparagine biosynthetic process from oxaloacetate	The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate.	got7fsn_ti	asparagine formation from oxaloacetate|asparagine anabolism from oxaloacetate|asparagine synthesis from oxaloacetate											MetaCyc:ASPARAGINE-BIOSYNTHESIS		biological_process											owl:Class	
GO:0043649	biolink:NamedThing	dicarboxylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.	got7fsn_ti	dicarboxylic acid catabolism|dicarboxylic acid breakdown|dicarboxylate catabolism|dicarboxylic acid degradation|dicarboxylate catabolic process													biological_process											owl:Class	
GO:0032880	biolink:NamedThing	regulation of protein localization	Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.	got7fsn_ti	regulation of protein localisation													biological_process											owl:Class	
GO:0032608	biolink:NamedThing	interferon-beta production	The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interferon-beta biosynthetic process|IFNB production|IFN-beta production|interferon-beta secretion				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0045350|GO:0035546			biological_process											owl:Class	
GO:0106386	biolink:NamedThing	(3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity	Catalysis of the reaction: 3R-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.	got7fsn_ti							hjd	2021-07-01T18:41:23Z				EC:1.1.1.n12|RHEA:32711		molecular_function											owl:Class	
GO:0008063	biolink:NamedThing	Toll signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	Tl signalling pathway|Toll signalling pathway|Tl signaling pathway													biological_process											owl:Class	
GO:0005643	biolink:NamedThing	nuclear pore	A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.	got7fsn_ti	nuclear pore complex|nucleopore|nuclear pore membrane protein|NPC										GO:0005644	Wikipedia:Nuclear_pore|NIF_Subcellular:sao220861693		cellular_component											owl:Class	
GO:0009511	biolink:NamedThing	plasmodesmatal endoplasmic reticulum	Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells.	got7fsn_ti	plasmodesmatal ER													cellular_component											owl:Class	
GO:0031085	biolink:NamedThing	BLOC-3 complex	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0031082	biolink:NamedThing	BLOC complex	Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.	got7fsn_ti	BLOC-1 related complex													cellular_component											owl:Class	
GO:0019931	biolink:NamedThing	protein-chromophore linkage via peptidyl-N6-3-dehydroretinal-L-lysine	The modification of peptidyl-lysine to form N6-3,4-didehydroretinylidene-L-lysine.	got7fsn_ti												RESID:AA0312		biological_process											owl:Class	
GO:0070006	biolink:NamedThing	metalloaminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681												molecular_function											owl:Class	
GO:0047955	biolink:NamedThing	glycerol dehydrogenase (acceptor) activity	Catalysis of the reaction: A + glycerol = AH(2) + glycerone.	got7fsn_ti	glycerol:(acceptor) 1-oxidoreductase activity|glycerol:acceptor 1-oxidoreductase activity											RHEA:17493|EC:1.1.99.22|MetaCyc:GLYCEROL-DEHYDROGENASE-ACCEPTOR-RXN|KEGG_REACTION:R01045		molecular_function											owl:Class	
GO:0055003	biolink:NamedThing	cardiac myofibril assembly	The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.	got7fsn_ti	cardiac myofibril development|heart myofibril assembly|cardiac myofibril morphogenesis													biological_process											owl:Class	
GO:0030239	biolink:NamedThing	myofibril assembly	Formation of myofibrils, the repeating units of striated muscle.	got7fsn_ti														biological_process											owl:Class	
GO:1990191	biolink:NamedThing	cobalamin transport complex	Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD.	got7fsn_ti	BtuCDF complex|cobalamin-transporting BtuCDF complex|vitamin B12 transport complex|vitamin B12-transporting BtuCDF complex						bhm	2013-09-12T14:20:19Z						cellular_component											owl:Class	
GO:0000293	biolink:NamedThing	ferric-chelate reductase activity	Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe3+-siderophore + electron acceptor.	got7fsn_ti	iron chelate reductase activity|ferric chelate reductase activity	https://github.com/geneontology/go-ontology/issues/21029												molecular_function											owl:Class	
GO:0071609	biolink:NamedThing	chemokine (C-C motif) ligand 5 production	The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	Regulated upon Activation, Normal T-cell Expressed, and Secreted production|CCL5 production|RANTES production						mah	2010-02-05T04:32:35Z						biological_process											owl:Class	
GO:1990679	biolink:NamedThing	histone H4-K12 deacetylation	The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone.	got7fsn_ti							al	2015-03-02T15:40:44Z						biological_process											owl:Class	
GO:0070933	biolink:NamedThing	histone H4 deacetylation	The modification of histone H4 by the removal of one or more acetyl groups.	got7fsn_ti							mah	2009-09-16T04:53:06Z						biological_process											owl:Class	
GO:0072166	biolink:NamedThing	posterior mesonephric tubule development	The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.	got7fsn_ti							mah	2010-02-26T01:47:50Z						biological_process											owl:Class	
GO:0030621	biolink:NamedThing	U4 snRNA binding	Binding to a U4 small nuclear RNA (U4 snRNA).	got7fsn_ti														molecular_function											owl:Class	
GO:0090682	biolink:NamedThing	GPCR bitter taste receptor activity	A G protein-coupled receptor activity that is responsible for the sense of bitter taste.	got7fsn_ti	G-protein coupled receptor bitter taste receptor activity|G protein-coupled receptor bitter taste receptor activity						tb	2016-05-20T15:49:18Z						molecular_function											owl:Class	
GO:0090681	biolink:NamedThing	GPCR taste receptor activity	A G protein-coupled receptor activity that is responsible for the sense of taste.	got7fsn_ti	G-protein-coupled taste receptor activity|G-protein coupled taste receptor activity						tb	2016-05-20T15:47:18Z						molecular_function											owl:Class	
GO:0047838	biolink:NamedThing	D-xylose 1-dehydrogenase (NAD) activity	Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH.	got7fsn_ti	D-xylose:NAD+ 1-oxidoreductase activity|NAD-D-xylose dehydrogenase activity|NAD-D-xylose|NAD-linked D-xylose dehydrogenase activity|(NAD)-linked D-xylose dehydrogenase activity|D-xylose dehydrogenase activity											MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN|RHEA:13861|EC:1.1.1.175		molecular_function											owl:Class	
GO:0071973	biolink:NamedThing	bacterial-type flagellum-dependent cell motility	Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.	got7fsn_ti	flagellin-based flagellar cell motility|bacterial-type flagellar cell motility						mah	2010-10-21T12:00:53Z						biological_process											owl:Class	
GO:0097588	biolink:NamedThing	archaeal or bacterial-type flagellum-dependent cell motility	Cell motility due to movement of bacterial- or archaeal-type flagella.	got7fsn_ti					Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. This term was added for mapping to the UniProt keyword "flagellar rotation". For manual annotation, please use one of the child terms of GO:0097588 that refer specifically to either archaeal- or bacterial-type flagella.		pr	2014-03-25T16:51:19Z						biological_process											owl:Class	
GO:0003095	biolink:NamedThing	pressure natriuresis	The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).	got7fsn_ti														biological_process											owl:Class	
GO:0034669	biolink:NamedThing	integrin alpha4-beta7 complex	An integrin complex that comprises one alpha4 subunit and one beta7 subunit.	got7fsn_ti	ITGA4-ITGB7 complex|alpha4-beta7 integrin complex													cellular_component											owl:Class	
GO:0102452	biolink:NamedThing	bisdemethoxycurcumin synthase activity	Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide.	got7fsn_ti												RHEA:34803|MetaCyc:RXN-13958|EC:2.3.1.211		molecular_function											owl:Class	
GO:0021892	biolink:NamedThing	cerebral cortex GABAergic interneuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0050462	biolink:NamedThing	N-acetylneuraminate synthase activity	Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate.	got7fsn_ti	N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity|NeuAc synthase activity|N-acetylneuraminic acid synthase activity|(NANA)condensing enzyme activity|phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)											MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN|EC:2.5.1.56|RHEA:19273		molecular_function											owl:Class	
GO:0003958	biolink:NamedThing	NADPH-hemoprotein reductase activity	Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.	got7fsn_ti	NADPH--cytochrome c reductase activity|cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent) activity|NADPH:P450 reductase activity|dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity|CPR activity|reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate) activity|cytochrome P450 reductase activity|NADPH--cytochrome P450 oxidoreductase activity|NADPH:cytochrome P450 reductase activity|NADPH--ferricytochrome c oxidoreductase activity|reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity|NADPH--ferrihemoprotein reductase activity|ferrihemoprotein P-450 reductase activity|NADPH-dependent cytochrome c reductase activity|POR|NADPH:P-450 reductase activity|TPNH-cytochrome c reductase activity|NADPH:ferrihemoprotein oxidoreductase activity|NADP--cytochrome reductase activity|NADPH--cytochrome c oxidoreductase activity|cytochrome P-450 reductase activity|NADPH-cytochrome P-450 oxidoreductase activity|TPNH(2) cytochrome c reductase activity|NADP--cytochrome c reductase activity|aldehyde reductase (NADPH-dependent) activity|NADPH:cytochrome c reductase activity|NADPH:hemoprotein oxidoreductase activity|NADPH-cytochrome p-450 reductase activity|TPNH2 cytochrome c reductase activity|NADPH-ferrihemoprotein reductase activity|NADPH--cytochrome P450 reductase activity|FAD-cytochrome c reductase activity											Reactome:R-HSA-76494|RHEA:24040|MetaCyc:NADPH--FERRIHEMOPROTEIN-REDUCTASE-RXN|EC:1.6.2.4		molecular_function											owl:Class	
GO:0052660	biolink:NamedThing	R-lactaldehyde reductase activity	Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+.	got7fsn_ti	D-lactaldehyde:propanediol oxidoreductase activity|(R)-propane-1,2-diol:NAD+ oxidoreductase activity											MetaCyc:RXN-8641|RHEA:23872|KEGG_REACTION:R03080		molecular_function											owl:Class	
GO:0019254	biolink:NamedThing	carnitine metabolic process, CoA-linked	The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA.	got7fsn_ti	carnitine metabolism, CoA-linked											MetaCyc:CARNMET-PWY		biological_process											owl:Class	
GO:0009437	biolink:NamedThing	carnitine metabolic process	The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	got7fsn_ti	vitamin Bt metabolic process|carnitine metabolism|vitamin Bt metabolism													biological_process											owl:Class	
GO:0035899	biolink:NamedThing	negative regulation of blood coagulation in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.	got7fsn_ti	inhibition of blood coagulation in other organism|suppression of blood coagulation in other organism|downregulation of blood coagulation in other organism|down-regulation of blood coagulation in other organism|negative regulation of blood clotting in other organism						bf	2011-06-22T09:17:54Z						biological_process											owl:Class	
GO:0035806	biolink:NamedThing	modulation of blood coagulation in other organism	Any process in which an organism modulates the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.	got7fsn_ti	modulation by organism of blood coagulation in other organism|regulation by organism of blood clotting in other organism|regulation of blood coagulation in other organism|modulation by organism of blood clotting in other organism|regulation of blood clotting in other organism						bf	2011-04-20T11:38:49Z						biological_process											owl:Class	
GO:0047348	biolink:NamedThing	glycerol-3-phosphate cytidylyltransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate.	got7fsn_ti	cytidine diphosphoglycerol pyrophosphorylase activity|CDP-glycerol diphosphorylase activity|Gro-PCT|CDP-glycerol pyrophosphorylase activity|cytidine diphosphate glycerol pyrophosphorylase activity|CTP:glycerol-3-phosphate cytidylyltransferase activity|CTP:sn-glycerol-3-phosphate cytidylyltransferase activity|CTP:glycerol 3-phosphate cytidylyltransferase activity											MetaCyc:2.7.7.39-RXN|RHEA:13361|KEGG_REACTION:R00856|EC:2.7.7.39		molecular_function											owl:Class	
GO:0050918	biolink:NamedThing	positive chemotaxis	The directed movement of a motile cell or organism towards a higher concentration of a chemical.	got7fsn_ti	chemoattraction													biological_process											owl:Class	
GO:0046543	biolink:NamedThing	development of secondary female sexual characteristics	The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0035503	biolink:NamedThing	ureter part of ureteric bud development	The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.	got7fsn_ti							bf	2010-04-29T03:23:42Z						biological_process											owl:Class	
GO:0090491	biolink:NamedThing	N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)	Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O.	got7fsn_ti							tb	2012-10-16T16:27:19Z						molecular_function											owl:Class	
GO:0018825	biolink:NamedThing	triethanolamine lyase activity	Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde.	got7fsn_ti												UM-BBD_enzymeID:e0421		molecular_function											owl:Class	
GO:0016843	biolink:NamedThing	amine-lyase activity	Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.	got7fsn_ti												EC:4.3.3.-		molecular_function											owl:Class	
GO:0018876	biolink:NamedThing	benzonitrile metabolic process	The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin.	got7fsn_ti	benzonitrile metabolism											UM-BBD_pathwayID:bzn		biological_process											owl:Class	
GO:0072177	biolink:NamedThing	mesonephric duct development	The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros.	got7fsn_ti	Wolffian duct development						mah	2010-02-26T02:32:22Z						biological_process											owl:Class	
GO:0072176	biolink:NamedThing	nephric duct development	The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.	got7fsn_ti							mah	2010-02-26T02:27:31Z						biological_process											owl:Class	
GO:0006953	biolink:NamedThing	acute-phase response	An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals.	got7fsn_ti														biological_process											owl:Class	
GO:0008770	biolink:NamedThing	[acyl-carrier-protein] phosphodiesterase activity	Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein.	got7fsn_ti	holo-acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity|ACP phosphodiesterase activity|ACP hydrolyase activity|[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase activity|acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity|AcpH|acyl-carrier-protein phosphodiesterase activity|[acyl-carrier protein] phosphodiesterase activity											EC:3.1.4.14|MetaCyc:3.1.4.14-RXN|RHEA:20537		molecular_function											owl:Class	
GO:0036091	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	got7fsn_ti							bf	2012-01-10T02:54:43Z						biological_process											owl:Class	
GO:0043619	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	got7fsn_ti														biological_process											owl:Class	
GO:0030952	biolink:NamedThing	establishment or maintenance of cytoskeleton polarity	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures.	got7fsn_ti	cytoskeleton polarization													biological_process											owl:Class	
GO:0047969	biolink:NamedThing	glyoxylate oxidase activity	Catalysis of the reaction: glyoxylate + H(2)O + O(2) = H(2)O(2) + H(+) + oxalate.	got7fsn_ti	glyoxylate:oxygen oxidoreductase activity											MetaCyc:GLYOXYLATE-OXIDASE-RXN|RHEA:14837|KEGG_REACTION:R00466|EC:1.2.3.5|Reactome:R-HSA-389862		molecular_function											owl:Class	
GO:0015193	biolink:NamedThing	L-proline transmembrane transporter activity	Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid.	got7fsn_ti	proline/glycine/betaine:hydrogen/sodium symporter activity|L-proline permease activity|L-proline transporter activity|glycine betaine/proline porter activity										GO:0005296	Reactome:R-HSA-8870354		molecular_function											owl:Class	
GO:0060410	biolink:NamedThing	negative regulation of acetylcholine metabolic process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0097233	biolink:NamedThing	alveolar lamellar body membrane	The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.	got7fsn_ti							pr	2012-01-26T10:30:24Z						cellular_component											owl:Class	
GO:1990523	biolink:NamedThing	bone regeneration	The regrowth of bone following its loss or destruction.	got7fsn_ti							sl	2014-10-30T15:47:39Z						biological_process											owl:Class	
GO:0061326	biolink:NamedThing	renal tubule development	The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.	got7fsn_ti							dph	2010-09-28T12:50:43Z						biological_process											owl:Class	
GO:0050061	biolink:NamedThing	long-chain-aldehyde dehydrogenase activity	Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.	got7fsn_ti	long-chain-aldehyde:NAD+ oxidoreductase activity|long-chain fatty aldehyde dehydrogenase activity|long-chain aliphatic aldehyde dehydrogenase activity|fatty aldehyde:NAD+ oxidoreductase activity											EC:1.2.1.48|UM-BBD_reactionID:r1404|RHEA:10652|MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:1990732	biolink:NamedThing	pyrenoid	A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation.	got7fsn_ti							pr	2015-04-24T12:44:52Z				Wikipedia:Pyrenoid		cellular_component											owl:Class	
GO:0061849	biolink:NamedThing	telomeric G-quadruplex DNA binding	Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.	got7fsn_ti														molecular_function											owl:Class	
GO:0072064	biolink:NamedThing	long descending thin limb development	The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.	got7fsn_ti							mah	2010-01-25T04:13:17Z						biological_process											owl:Class	
GO:0072022	biolink:NamedThing	descending thin limb development	The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle.	got7fsn_ti							mah	2010-01-25T02:37:47Z						biological_process											owl:Class	
GO:0071529	biolink:NamedThing	cementum mineralization	The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum.	got7fsn_ti	cementum formation						mah	2010-01-07T04:18:54Z						biological_process											owl:Class	
GO:0032596	biolink:NamedThing	protein transport into membrane raft	The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	got7fsn_ti	protein translocation into membrane raft|receptor transport into membrane raft|protein transport into lipid raft|receptor translocation into membrane raft													biological_process											owl:Class	
GO:0032594	biolink:NamedThing	protein transport within lipid bilayer	The directed movement of a protein from one location to another within a lipid bilayer.	got7fsn_ti	protein translocation within membrane|receptor transport within lipid bilayer|receptor translocation within membrane													biological_process											owl:Class	
GO:0044241	biolink:NamedThing	lipid digestion	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0007586	biolink:NamedThing	digestion	The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	got7fsn_ti												Wikipedia:Digestion		biological_process											owl:Class	
GO:0070079	biolink:NamedThing	histone H4-R3 demethylation	The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone.	got7fsn_ti														biological_process											owl:Class	
GO:0030183	biolink:NamedThing	B cell differentiation	The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.	got7fsn_ti	B-cell differentiation|B-lymphocyte differentiation|B lymphocyte differentiation|B cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.						GO:0042115			biological_process											owl:Class	
GO:0044687	biolink:NamedThing	geranylfarnesyl diphosphate synthase activity	Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate.	got7fsn_ti							jl	2012-08-15T14:20:25Z				RHEA:25694|MetaCyc:RXN-8813|EC:2.5.1.81		molecular_function											owl:Class	
GO:0005221	biolink:NamedThing	intracellular cyclic nucleotide activated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.	got7fsn_ti												Reactome:R-HSA-2514867		molecular_function											owl:Class	
GO:0003431	biolink:NamedThing	growth plate cartilage chondrocyte development	The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.	got7fsn_ti							dph	2009-12-22T12:32:49Z						biological_process											owl:Class	
GO:0003433	biolink:NamedThing	chondrocyte development involved in endochondral bone morphogenesis	The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.	got7fsn_ti							dph	2009-12-22T12:42:44Z						biological_process											owl:Class	
GO:0035643	biolink:NamedThing	L-DOPA receptor activity	Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine.	got7fsn_ti	L-dopa receptor activity|L-beta-(3,4-Dihydroxyphenyl)alanine receptor activity						bf	2011-01-20T10:34:23Z						molecular_function											owl:Class	
GO:0061231	biolink:NamedThing	mesonephric glomerulus vasculature development	The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.	got7fsn_ti							dph	2010-08-19T02:47:06Z						biological_process											owl:Class	
GO:0110009	biolink:NamedThing	formin-nucleated actin cable organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.	got7fsn_ti							kmv							biological_process											owl:Class	
GO:0061572	biolink:NamedThing	actin filament bundle organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.	got7fsn_ti	actin filament cable organization						dph	2013-08-02T11:24:11Z						biological_process											owl:Class	
GO:0009790	biolink:NamedThing	embryo development	The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.	got7fsn_ti	embryonal development|embryogenesis and morphogenesis|embryogenesis										GO:0009795	Wikipedia:Embryogenesis		biological_process											owl:Class	
GO:0018652	biolink:NamedThing	toluene-sulfonate methyl-monooxygenase activity	Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol.	got7fsn_ti	toluene-sulphonate methyl-monooxygenase activity											MetaCyc:TSMOS-RXN|UM-BBD_reactionID:r0290|RHEA:51024		molecular_function											owl:Class	
GO:0004174	biolink:NamedThing	electron-transferring-flavoprotein dehydrogenase activity	Catalysis of the reaction: a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H+ + oxidized [electron-transfer flavoprotein].	got7fsn_ti	electron transfer flavoprotein Q oxidoreductase activity|electron transfer flavoprotein dehydrogenase activity|electron transfer flavoprotein-ubiquinone oxidoreductase activity|electron-transferring-flavoprotein:ubiquinone oxidoreductase activity|electron transfer flavoprotein reductase activity|ETF:ubiquinone oxidoreductase activity|ETF dehydrogenase activity|ETF-QO activity|ETF-ubiquinone oxidoreductase activity											MetaCyc:1.5.5.1-RXN|EC:1.5.5.1|RHEA:24052|Reactome:R-HSA-169270		molecular_function											owl:Class	
GO:0016649	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound.	got7fsn_ti												EC:1.5.5.-		molecular_function											owl:Class	
GO:1990257	biolink:NamedThing	piccolo-bassoon transport vesicle	A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bassoon transport vesicles (or PTVs) range in size from approximately 80 nm in diameter for dense core vesicles to 130 nm by 220 nm in area for aggregates. They are packaged via the trans-Golgi network before being transported through the axon.	got7fsn_ti	PTV						pr	2013-12-19T14:12:09Z						cellular_component											owl:Class	
GO:0051383	biolink:NamedThing	kinetochore organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	got7fsn_ti	kinetochore organization and biogenesis|kinetochore organisation													biological_process											owl:Class	
GO:0002122	biolink:NamedThing	fear-induced aggressive behavior	Aggressive behavior associated with attempts to flee from a threat.	got7fsn_ti	fear-induced aggression													biological_process											owl:Class	
GO:0002118	biolink:NamedThing	aggressive behavior	A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual.	got7fsn_ti	aggression											Wikipedia:Aggression		biological_process											owl:Class	
GO:0140489	biolink:NamedThing	molecular template activity	The action of a molecule that provides a shape or a sequence mimicking or complementary to the final product, providing template for copying the original molecule's shape or sequence.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19709					pg	2020-07-01T08:42:18Z						molecular_function											owl:Class	
GO:0090064	biolink:NamedThing	activation of microtubule nucleation	Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.	got7fsn_ti							tb	2009-08-12T11:36:15Z						biological_process											owl:Class	
GO:0090063	biolink:NamedThing	positive regulation of microtubule nucleation	Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.	got7fsn_ti							tb	2009-08-12T11:33:09Z						biological_process											owl:Class	
GO:0048769	biolink:NamedThing	sarcomerogenesis	The process in which sarcomeres are added in series within a fiber.	got7fsn_ti	myofibril production													biological_process											owl:Class	
GO:0001661	biolink:NamedThing	conditioned taste aversion	A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.	got7fsn_ti												Wikipedia:Taste_aversion|Wikipedia:Conditioned_taste_aversion		biological_process											owl:Class	
GO:0044265	biolink:NamedThing	cellular macromolecule catabolic process	The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.	got7fsn_ti	cellular macromolecule catabolism|cellular macromolecule breakdown|cellular macromolecule degradation|cellular biopolymer catabolic process										GO:0034962			biological_process											owl:Class	
GO:0071084	biolink:NamedThing	alpha2-beta1 integrin-CD47 complex	A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.	got7fsn_ti	ITGA2-ITGB1-CD47 complex						mah	2009-11-06T04:44:35Z						cellular_component											owl:Class	
GO:2001227	biolink:NamedThing	quercitrin binding	Binding to quercitrin.	got7fsn_ti							tb	2011-11-18T09:58:37Z						molecular_function											owl:Class	
GO:0038032	biolink:NamedThing	termination of G protein-coupled receptor signaling pathway	The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal.	got7fsn_ti	termination of G-protein coupled receptor signaling pathway|termination of G-protein coupled receptor signalling pathway|termination of GPCR signaling pathway						bf	2011-09-16T10:31:21Z						biological_process											owl:Class	
GO:0009220	biolink:NamedThing	pyrimidine ribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine ribonucleotide formation|pyrimidine ribonucleotide anabolism|pyrimidine ribonucleotide biosynthesis|pyrimidine ribonucleotide synthesis											MetaCyc:PWY0-162		biological_process											owl:Class	
GO:0070439	biolink:NamedThing	Mad-Max-mSin3A complex	A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.	got7fsn_ti														cellular_component											owl:Class	
GO:0038189	biolink:NamedThing	neuropilin signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	Npn signaling						bf	2013-08-01T16:02:10Z						biological_process											owl:Class	
GO:0110059	biolink:NamedThing	negative regulation of blood vessel endothelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation.	got7fsn_ti							kmv	2017-10-23T14:47:29Z						biological_process											owl:Class	
GO:0045602	biolink:NamedThing	negative regulation of endothelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.	got7fsn_ti	inhibition of endothelial cell differentiation|down-regulation of endothelial cell differentiation|down regulation of endothelial cell differentiation|downregulation of endothelial cell differentiation													biological_process											owl:Class	
GO:0052063	biolink:NamedThing	induction by symbiont of defense-related host nitric oxide production	The activation by a symbiont of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|up regulation by symbiont of defense-related host nitric oxide production|activation by organism of defense-related host nitric oxide production|positive regulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|positive regulation by organism of defense-related host NO production|induction by organism of defense-related host NO production|positive regulation by symbiont of defense-related host nitric oxide production|up-regulation by symbiont of defense-related host nitric oxide production|activation by symbiont of defense-related host nitric oxide production|upregulation by symbiont of defense-related host nitric oxide production|activation by organism of defense-related host NO production|stimulation by symbiont of defense-related host nitric oxide production										GO:0052345|GO:0052347|GO:0052263			biological_process											owl:Class	
GO:0045916	biolink:NamedThing	negative regulation of complement activation	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation.	got7fsn_ti	inhibition of complement activation|downregulation of complement activation|down regulation of complement activation|down-regulation of complement activation|negative regulation of complement cascade													biological_process											owl:Class	
GO:0033653	biolink:NamedThing	host cell chloroplast part	Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	host chloroplast component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									cellular_component											owl:Class	
GO:0050525	biolink:NamedThing	cutinase activity	Catalysis of the reaction: cutin + H2O = cutin monomers.	got7fsn_ti	cutin hydrolase activity											EC:3.1.1.74|MetaCyc:3.1.1.74-RXN		molecular_function											owl:Class	
GO:0060987	biolink:NamedThing	lipid tube	A macromolecular complex that contains a tube of lipid surrounded by a protein coat.	got7fsn_ti							dph	2010-01-11T01:54:25Z						cellular_component											owl:Class	
GO:0032994	biolink:NamedThing	protein-lipid complex	A macromolecular complex containing separate protein and lipid molecules.  Separate in this context means not covalently bound to each other.	got7fsn_ti					Macromolecular complexes in which the lipid component is all covalently bound to protein are not considered protein-lipid complexes.									cellular_component											owl:Class	
GO:0017050	biolink:NamedThing	D-erythro-sphingosine kinase activity	Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP.	got7fsn_ti	sphingosine kinase activity											Reactome:R-HSA-9695949|Reactome:R-HSA-428273|RHEA:35847|Reactome:R-HSA-9625814|Reactome:R-HSA-5218845|MetaCyc:RXN3DJ-11417		molecular_function											owl:Class	
GO:0021715	biolink:NamedThing	inferior olivary nucleus formation	The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	got7fsn_ti	inferior olive biosynthesis|inferior olive formation													biological_process											owl:Class	
GO:0033896	biolink:NamedThing	ribonuclease IX activity	Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.	got7fsn_ti	poly(U)- and poly(C)-specific endoribonuclease activity											MetaCyc:3.1.26.10-RXN|EC:3.1.26.10		molecular_function											owl:Class	
GO:0035172	biolink:NamedThing	hemocyte proliferation	The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.	got7fsn_ti	arthropod blood cell proliferation													biological_process											owl:Class	
GO:2000828	biolink:NamedThing	regulation of parathyroid hormone secretion	Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.	got7fsn_ti	regulation of PTH secretion|regulation of parathormone secretion|regulation of parathyrin secretion						bf	2011-07-26T08:37:53Z						biological_process											owl:Class	
GO:0008812	biolink:NamedThing	choline dehydrogenase activity	Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde.	got7fsn_ti	choline:acceptor 1-oxidoreductase activity|choline-cytochrome c reductase activity|choline:(acceptor) 1-oxidoreductase activity|choline:(acceptor) oxidoreductase activity|choline oxidase activity											KEGG_REACTION:R01025|EC:1.1.99.1|MetaCyc:CHD-RXN|Reactome:R-HSA-6797961|RHEA:17433		molecular_function											owl:Class	
GO:0098024	biolink:NamedThing	virus tail, fiber	The fibrous region of the virus tail used to scan, recognize and attach to the host cell.	got7fsn_ti	bacteriophage tail fiber				For tailed bacteriophages, fibers typically bind to particular Lipopolysaccharide (LPS), polysaccharide or protein receptors on the cell surface.		bm	2012-07-19T14:14:50Z						cellular_component											owl:Class	
GO:0034585	biolink:NamedThing	21U-RNA metabolic process	The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.	got7fsn_ti	21U-RNA metabolism													biological_process											owl:Class	
GO:0140298	biolink:NamedThing	endocytic iron import into cell	Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis.	got7fsn_ti	iron import into cell by endocytosis						pg	2018-12-10T10:31:31Z						biological_process											owl:Class	
GO:0044500	biolink:NamedThing	envenomation resulting in negative regulation of blood pressure in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism.	got7fsn_ti	hypotensive activity in other organism						jl	2012-02-01T02:40:50Z						biological_process											owl:Class	
GO:0044498	biolink:NamedThing	envenomation resulting in modulation of blood pressure in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism.	got7fsn_ti	envenomation resulting in regulation of blood pressure in other organism						jl	2012-02-01T02:21:27Z						biological_process											owl:Class	
GO:0102721	biolink:NamedThing	ubiquinol:oxygen oxidoreductase activity	Catalysis of the reaction: O2 + 2 an ubiquinol = 2 H2O + 2 an ubiquinone.	got7fsn_ti												RHEA:30255|MetaCyc:RXN-6883|EC:1.10.3.11		molecular_function											owl:Class	
GO:0016682	biolink:NamedThing	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen.	got7fsn_ti	laccase activity											EC:1.10.3.-		molecular_function											owl:Class	
GO:0061389	biolink:NamedThing	regulation of direction of cell growth	Any process that modulates the direction of cell growth.	got7fsn_ti							dph	2011-07-14T10:19:46Z						biological_process											owl:Class	
GO:0016890	biolink:NamedThing	site-specific endodeoxyribonuclease activity, specific for altered base	Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks.	got7fsn_ti												EC:3.1.25.-		molecular_function											owl:Class	
GO:0050075	biolink:NamedThing	maleate hydratase activity	Catalysis of the reaction: (R)-malate = H(2)O + maleate.	got7fsn_ti	malease activity|(R)-malate hydro-lyase activity|D-malate hydro-lyase activity|(R)-malate hydro-lyase (maleate-forming)											KEGG_REACTION:R02419|EC:4.2.1.31|RHEA:23692|MetaCyc:MALEATE-HYDRATASE-RXN		molecular_function											owl:Class	
GO:0046804	biolink:NamedThing	peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide	The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine.	got7fsn_ti	peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulphoxide											RESID:AA0330		biological_process											owl:Class	
GO:0019939	biolink:NamedThing	peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically.	got7fsn_ti	peptidyl-S-palmitoleyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-palmitoleyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-palmitoleyl-L-cysteine synthesis from peptidyl-cysteine											RESID:AA0308		biological_process											owl:Class	
GO:0045234	biolink:NamedThing	protein palmitoleylation	The covalent attachment of a palmitoleyl group to a protein.	got7fsn_ti	protein amino acid palmitoleylation										GO:0045235			biological_process											owl:Class	
GO:0070067	biolink:NamedThing	syntaxin-6-syntaxin-16-Vti1a complex	A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).	got7fsn_ti														cellular_component											owl:Class	
GO:0047253	biolink:NamedThing	alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.	got7fsn_ti	UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase VI activity|N-acetylglucosaminyltransferase VI activity|uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI|uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI activity|alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyl-transferase activity											EC:2.4.1.201|RHEA:19945|MetaCyc:2.4.1.201-RXN		molecular_function											owl:Class	
GO:0102497	biolink:NamedThing	scyllo-inositol dehydrogenase (NADP+) activity	Catalysis of the reaction: scyllo-inositol + NADP <=> 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-14347|EC:1.1.1.371|RHEA:39063		molecular_function											owl:Class	
GO:0043006	biolink:NamedThing	activation of phospholipase A2 activity by calcium-mediated signaling	A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal.	got7fsn_ti	calcium-dependent phospholipase A2 activation|calcium-dependent activation of phospholipase A2|activation of phospholipase A2 activity by calcium-mediated signalling													biological_process											owl:Class	
GO:0030237	biolink:NamedThing	female sex determination	The specification of female sex of an individual organism.	got7fsn_ti														biological_process											owl:Class	
GO:0033750	biolink:NamedThing	ribosome localization	A process in which a ribosome is transported to, and/or maintained in, a specific location.	got7fsn_ti	establishment of ribosome localisation|establishment of ribosome localization|ribosome localisation										GO:0033753			biological_process											owl:Class	
GO:0103092	biolink:NamedThing	methylthioalkylmalate isomerase activity	Catalysis of the reaction: 2-(7'-methylthio)heptylmalate <=> 3-(7'-methylthio)heptylmalate.	got7fsn_ti												MetaCyc:RXNQT-4176		molecular_function											owl:Class	
GO:0031951	biolink:NamedThing	positive regulation of glucocorticoid catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.	got7fsn_ti	stimulation of glucocorticoid catabolic process|up-regulation of glucocorticoid catabolic process|activation of glucocorticoid catabolic process|upregulation of glucocorticoid catabolic process|up regulation of glucocorticoid catabolic process													biological_process											owl:Class	
GO:0021894	biolink:NamedThing	cerebral cortex GABAergic interneuron development	The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0035451	biolink:NamedThing	extrinsic component of stromal side of plastid thylakoid membrane	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to stromal leaflet of plastid thylakoid membrane|peripheral to stromal side of plastid thylakoid membrane|extrinsic to stromal side of plastid thylakoid membrane						bf	2010-04-16T10:18:01Z						cellular_component											owl:Class	
GO:0035449	biolink:NamedThing	extrinsic component of plastid thylakoid membrane	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	peripheral to plastid thylakoid membrane|extrinsic to plastid thylakoid membrane						bf	2010-04-16T10:14:24Z						cellular_component											owl:Class	
GO:0035102	biolink:NamedThing	PRC1 complex	A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.	got7fsn_ti	Polycomb repressive complex 1				In Drosophila the core subunits are Pc (Polycomb), Psc (Posterior sex combs), Ph (Polyhomeotic) and Sce (Sex comb extra). In mammals, which have several orthologs for each of the Drosophila core proteins, a family of distinct PRC1-like complexes seem to exist which contain at least some PcG proteins in mutually exclusive manner.									cellular_component											owl:Class	
GO:1990455	biolink:NamedThing	PTEN phosphatase complex	A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.	got7fsn_ti	phosphatase and tensin homolog deleted on chromosome ten homodimer|phosphatase and tensin homolog|phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer				An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay).		bhm	2014-08-13T10:21:20Z						cellular_component											owl:Class	
GO:0009864	biolink:NamedThing	induced systemic resistance, jasmonic acid mediated signaling pathway	The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance.	got7fsn_ti	induced systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid mediated signaling pathway (induced systemic resistance)													biological_process											owl:Class	
GO:0005741	biolink:NamedThing	mitochondrial outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.	got7fsn_ti	mitochondrion outer membrane|outer mitochondrial membrane|outer mitochondrion membrane											Wikipedia:Outer_mitochondrial_membrane|NIF_Subcellular:sao1289741256		cellular_component											owl:Class	
GO:0031966	biolink:NamedThing	mitochondrial membrane	Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.	got7fsn_ti												NIF_Subcellular:sao1045389829		cellular_component											owl:Class	
GO:0071490	biolink:NamedThing	cellular response to far red light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti	cellular response to far red light stimulus						mah	2009-12-18T02:19:40Z						biological_process											owl:Class	
GO:0097110	biolink:NamedThing	scaffold protein binding	Binding to a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.	got7fsn_ti							pr	2011-07-28T05:16:53Z						molecular_function											owl:Class	
GO:0048655	biolink:NamedThing	anther wall tapetum morphogenesis	The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.	got7fsn_ti	differentiation of tapetal layer|tapetal layer morphogenesis|tapetum morphogenesis													biological_process											owl:Class	
GO:0008286	biolink:NamedThing	insulin receptor signaling pathway	The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.	got7fsn_ti	insulin receptor signalling pathway|daf-2 receptor signaling pathway													biological_process											owl:Class	
GO:0039588	biolink:NamedThing	suppression by virus of host antigen processing and presentation	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex.	got7fsn_ti	inhibition of host proteasome antigen processing by virus						bf	2012-05-04T04:34:52Z				VZ:815		biological_process											owl:Class	
GO:0002578	biolink:NamedThing	negative regulation of antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.	got7fsn_ti	downregulation of antigen processing and presentation|inhibition of antigen processing and presentation|down-regulation of antigen processing and presentation|down regulation of antigen processing and presentation													biological_process											owl:Class	
GO:0001081	biolink:NamedThing	nitrogen catabolite repression of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter by nitrogen catabolites						krc	2010-10-27T03:38:05Z						biological_process											owl:Class	
GO:0036209	biolink:NamedThing	9beta-pimara-7,15-diene oxidase activity	Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].	got7fsn_ti	9-beta-stemod-13(17)-ene oxidase activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.14.13.144.		bf	2012-04-25T11:11:55Z			GO:0102609	RHEA:31951|MetaCyc:RXN-15437|KEGG_REACTION:R09865|EC:1.14.14.111		molecular_function											owl:Class	
GO:1990072	biolink:NamedThing	TRAPPIII protein complex	A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins.	got7fsn_ti							bhm	2013-03-28T14:28:59Z						cellular_component											owl:Class	
GO:0035003	biolink:NamedThing	subapical complex	The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.	got7fsn_ti	SAC													cellular_component											owl:Class	
GO:0052701	biolink:NamedThing	cellular modified histidine metabolic process	The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	got7fsn_ti	modified histidine metabolism|cellular histidine derivative metabolic process|histidine derivative metabolic process|modified histidine metabolic process|cellular histidine derivative metabolism|cellular modified histidine metabolism							2011-08-01T03:47:00Z						biological_process											owl:Class	
GO:0046158	biolink:NamedThing	ocellus pigment metabolic process	The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.	got7fsn_ti	ocellus pigment metabolism													biological_process											owl:Class	
GO:1990274	biolink:NamedThing	mitotic actomyosin contractile ring disassembly	Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle.	got7fsn_ti	mitotic constriction ring disassembly|mitotic CAR disassembly|mitotic contractile actomyosin ring disassembly|mitotic actomyosin ring disassembly|mitotic cytokinetic ring disassembly						mah	2014-01-16T10:25:42Z						biological_process											owl:Class	
GO:0042181	biolink:NamedThing	ketone biosynthetic process	The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.	got7fsn_ti	ketone synthesis|ketone anabolism|ketone biosynthesis|ketone formation													biological_process											owl:Class	
GO:0061617	biolink:NamedThing	MICOS complex	Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.	got7fsn_ti	mitochondrial contact site and cristae organizing system|Fcj1 complex|MINOS complex|MitOS complex						dph	2014-04-14T07:18:13Z						cellular_component											owl:Class	
GO:1990522	biolink:NamedThing	tail spike morphogenesis	The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death.	got7fsn_ti							jl	2014-10-23T15:20:15Z				WBbt:0006979|WBbt:0008072		biological_process											owl:Class	
GO:0045765	biolink:NamedThing	regulation of angiogenesis	Any process that modulates the frequency, rate or extent of angiogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:0070119	biolink:NamedThing	ciliary neurotrophic factor binding	Binding to the cytokine ciliary neurotrophic factor.	got7fsn_ti	CNTF binding													molecular_function											owl:Class	
GO:0021569	biolink:NamedThing	rhombomere 3 development	The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0103083	biolink:NamedThing	methylthiobutylmalate isomerase activity	Catalysis of the reaction: 2-(4'-methylthio)butylmalate <=> 3-(4'-methylthio)butylmalate.	got7fsn_ti												MetaCyc:RXNQT-4167		molecular_function											owl:Class	
GO:0086044	biolink:NamedThing	atrial cardiac muscle cell to AV node cell communication by electrical coupling	The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti	atrial cardiomyocyte to AV node cell communication by electrical coupling|atrial cardiomyocyte to atrioventricular node cell communication by electrical coupling						dph	2011-11-15T02:51:29Z						biological_process											owl:Class	
GO:0086066	biolink:NamedThing	atrial cardiac muscle cell to AV node cell communication	The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti	atrial cardiomyocyte to AV node cell communication|atrial cardiomyocyte to atrioventricular node cell communication						dph	2011-11-22T09:05:09Z						biological_process											owl:Class	
GO:0018668	biolink:NamedThing	3-hydroxybenzoate 4-monooxygenase activity	Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+).	got7fsn_ti	3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)|3-hydroxybenzoate 4-hydroxylase activity											UM-BBD_reactionID:r0153|MetaCyc:3-HYDROXYBENZOATE-4-MONOOXYGENASE-RXN|RHEA:11480|KEGG_REACTION:R01628|EC:1.14.13.23		molecular_function											owl:Class	
GO:0051172	biolink:NamedThing	negative regulation of nitrogen compound metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.	got7fsn_ti	negative regulation of nitrogen metabolism|inhibition of nitrogen metabolic process|negative regulation of nitrogen metabolic process|downregulation of nitrogen metabolic process|down regulation of nitrogen metabolic process|down-regulation of nitrogen metabolic process													biological_process											owl:Class	
GO:0033575	biolink:NamedThing	protein glycosylation at cell surface	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid at the surface of a cell.	got7fsn_ti	protein amino acid glycosylation at cell surface													biological_process											owl:Class	
GO:0021753	biolink:NamedThing	superior salivary nucleus development	The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0021751	biolink:NamedThing	salivary nucleus development	The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0031490	biolink:NamedThing	chromatin DNA binding	Binding to DNA that is assembled into chromatin.	got7fsn_ti														molecular_function											owl:Class	
GO:0003682	biolink:NamedThing	chromatin binding	Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	got7fsn_ti	lamin/chromatin binding|microtubule/chromatin interaction|nuclear membrane vesicle binding to chromatin													molecular_function											owl:Class	
GO:0030951	biolink:NamedThing	establishment or maintenance of microtubule cytoskeleton polarity	Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.	got7fsn_ti														biological_process											owl:Class	
GO:0034840	biolink:NamedThing	3-hydroxymenthone dehydrogenase activity	Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r1185		molecular_function											owl:Class	
GO:0048172	biolink:NamedThing	regulation of short-term neuronal synaptic plasticity	A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.	got7fsn_ti					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:0072145	biolink:NamedThing	proximal convoluted tubule segment 1 cell development	The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure.	got7fsn_ti	S1 cell development						mah	2010-02-24T01:54:56Z						biological_process											owl:Class	
GO:0050371	biolink:NamedThing	tyrosine phenol-lyase activity	Catalysis of the reaction: L-tyrosine + H(2)O = NH(4)(+) + phenol + pyruvate.	got7fsn_ti	beta-tyrosinase activity|L-tyrosine phenol-lyase (deaminating)|L-tyrosine phenol-lyase (deaminating; pyruvate-forming)											MetaCyc:TYROSINE-PHENOL-LYASE-RXN|EC:4.1.99.2|KEGG_REACTION:R00728|RHEA:21704		molecular_function											owl:Class	
GO:0052714	biolink:NamedThing	mannosyl-inositol phosphorylceramide phospholipase activity	Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol.	got7fsn_ti							ai	2011-08-05T08:02:57Z						molecular_function											owl:Class	
GO:0052713	biolink:NamedThing	inositol phosphorylceramide phospholipase activity	Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol.	got7fsn_ti							ai	2011-08-05T04:51:03Z						molecular_function											owl:Class	
GO:0120205	biolink:NamedThing	photoreceptor proximal connecting cilium	The proximal region of the photoreceptor connecting cilium is similar to the transition zone of unspecialized primary cilia and houses several major transition zone complexes, including NPHP, MKS, and RPGR.	got7fsn_ti	photoreceptor PCC|PCC						krc	2019-05-10T22:47:08Z						cellular_component											owl:Class	
GO:0034543	biolink:NamedThing	5-aminosalicylate dioxygenase activity	Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate.	got7fsn_ti												UM-BBD_reactionID:r0809|EC:1.13.11.-		molecular_function											owl:Class	
GO:0044596	biolink:NamedThing	3-demethylubiquinol-10 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10.	got7fsn_ti							jl	2012-04-26T04:54:11Z				MetaCyc:RXN-9237|Reactome:R-HSA-2162186|RHEA:44412		molecular_function											owl:Class	
GO:0071928	biolink:NamedThing	tyramine signaling pathway	The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor.	got7fsn_ti	tyramine signalling pathway						mah	2010-09-28T01:20:10Z						biological_process											owl:Class	
GO:0007211	biolink:NamedThing	octopamine or tyramine signaling pathway	The series of molecular signals generated as a consequence of octopamine or tyramine binding to a cell surface receptor. Octopamine and tyramine are decarboxylation products of tyrosine, and are the invertebrate counterparts of the vertebrate adrenergic transmitters.	got7fsn_ti	octopamine or tyramine signalling pathway|octopamine/tyramine signaling pathway													biological_process											owl:Class	
GO:0014719	biolink:NamedThing	skeletal muscle satellite cell activation	The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor  such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.	got7fsn_ti														biological_process											owl:Class	
GO:0018510	biolink:NamedThing	phloroglucinol reductase activity	Catalysis of the reaction: dihydrophloroglucinol + NADP(+) = H(+) + NADPH + phloroglucinol.	got7fsn_ti	dihydrophloroglucinol:NADP+ oxidoreductase activity											UM-BBD_reactionID:r0007|RHEA:10080|EC:1.3.1.57|MetaCyc:R5-RXN|KEGG_REACTION:R05308		molecular_function											owl:Class	
GO:0033451	biolink:NamedThing	GUA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GUA codon.	got7fsn_ti	valine tRNA|GTA codon-amino acid adaptor activity				Note that in the standard genetic code, GTA codes for valine.									molecular_function											owl:Class	
GO:0034138	biolink:NamedThing	toll-like receptor 3 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 3.	got7fsn_ti	toll-like receptor 3 signalling pathway|TLR3 signaling pathway													biological_process											owl:Class	
GO:0003195	biolink:NamedThing	tricuspid valve formation	The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti							dph	2009-10-08T01:14:40Z						biological_process											owl:Class	
GO:0009032	biolink:NamedThing	thymidine phosphorylase activity	Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.	got7fsn_ti	thymidine-orthophosphate deoxyribosyltransferase activity|thymidine:phosphate deoxy-alpha-D-ribosyltransferase activity|thymidine:phosphate deoxy-D-ribosyltransferase activity|pyrimidine phosphorylase activity											RHEA:16037|EC:2.4.2.4|MetaCyc:THYM-PHOSPH-RXN		molecular_function											owl:Class	
GO:0036230	biolink:NamedThing	granulocyte activation	The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti							bf	2012-05-11T10:57:48Z						biological_process											owl:Class	
GO:0031682	biolink:NamedThing	G-protein gamma-subunit binding	Binding to a G-protein gamma subunit.	got7fsn_ti	G-gamma protein subunit binding													molecular_function											owl:Class	
GO:0048718	biolink:NamedThing	cibarial fish-trap bristle morphogenesis	The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.	got7fsn_ti	fish trap bristle morphogenesis													biological_process											owl:Class	
GO:0010166	biolink:NamedThing	wax metabolic process	The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids.	got7fsn_ti	wax metabolism													biological_process											owl:Class	
GO:0072060	biolink:NamedThing	outer medullary collecting duct development	The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.	got7fsn_ti							mah	2010-01-25T04:08:18Z						biological_process											owl:Class	
GO:0051982	biolink:NamedThing	copper-nicotianamine transmembrane transporter activity	Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other.	got7fsn_ti	Cu-NA chelate transporter activity													molecular_function											owl:Class	
GO:0021531	biolink:NamedThing	spinal cord radial glial cell differentiation	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti	radial glial cell differentiation in spinal cord													biological_process											owl:Class	
GO:0061116	biolink:NamedThing	ductus venosus closure	The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth.	got7fsn_ti							dph	2010-05-17T07:21:53Z						biological_process											owl:Class	
GO:0048845	biolink:NamedThing	venous blood vessel morphogenesis	The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.	got7fsn_ti	venous morphogenesis|vein morphogenesis													biological_process											owl:Class	
GO:0021548	biolink:NamedThing	pons development	The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	got7fsn_ti														biological_process											owl:Class	
GO:0000452	biolink:NamedThing	snoRNA guided rRNA 2'-O-methylation	The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation.	got7fsn_ti	snoRNA guided rRNA 2'-O-ribose methylation													biological_process											owl:Class	
GO:0047815	biolink:NamedThing	D-arabinonolactonase activity	Catalysis of the reaction: D-arabinono-1,4-lactone + H(2)O = D-arabinonate + H(+).	got7fsn_ti	D-arabinono-1,4-lactone lactonohydrolase activity											RHEA:23108|KEGG_REACTION:R02714|MetaCyc:D-ARABINONOLACTONASE-RXN|EC:3.1.1.30		molecular_function											owl:Class	
GO:0010118	biolink:NamedThing	stomatal movement	The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).	got7fsn_ti														biological_process											owl:Class	
GO:0097438	biolink:NamedThing	exit from dormancy	The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.	got7fsn_ti	release from dormancy						pr	2012-12-05T15:01:24Z						biological_process											owl:Class	
GO:0044820	biolink:NamedThing	mitotic telomere tethering at nuclear periphery	The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle.	got7fsn_ti							jl	2013-11-19T16:16:22Z						biological_process											owl:Class	
GO:0070319	biolink:NamedThing	Golgi to plasma membrane transport vesicle	A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.	got7fsn_ti	Golgi to plasma membrane constitutive secretory pathway transport vesicle|Golgi-plasma membrane transport vesicle													cellular_component											owl:Class	
GO:0061052	biolink:NamedThing	negative regulation of cell growth involved in cardiac muscle cell development	Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.	got7fsn_ti							dph	2010-02-25T01:11:30Z						biological_process											owl:Class	
GO:0018813	biolink:NamedThing	trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity	Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).	got7fsn_ti												RHEA:27389|EC:4.1.2.45|UM-BBD_enzymeID:e0257		molecular_function											owl:Class	
GO:0035784	biolink:NamedThing	nickel cation homeostasis	Any process involved in the maintenance of an internal steady state of nickel cations within an organism or cell.	got7fsn_ti	nickel homeostasis						bf	2011-04-05T09:55:14Z						biological_process											owl:Class	
GO:0072208	biolink:NamedThing	metanephric smooth muscle tissue development	The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.	got7fsn_ti							mah	2010-03-18T11:51:59Z						biological_process											owl:Class	
GO:0019576	biolink:NamedThing	aerobic fructose catabolic process	The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen.	got7fsn_ti	aerobic fructose catabolism|aerobic fructose degradation|aerobic fructose breakdown													biological_process											owl:Class	
GO:0006001	biolink:NamedThing	fructose catabolic process	The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose.	got7fsn_ti	fructose breakdown|fructose degradation|fructose catabolism													biological_process											owl:Class	
GO:0072536	biolink:NamedThing	interleukin-23 receptor complex	A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.	got7fsn_ti	IL-23 receptor complex						mah	2011-01-14T02:51:14Z						cellular_component											owl:Class	
GO:0016561	biolink:NamedThing	protein import into peroxisome matrix, translocation	The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation.	got7fsn_ti	peroxisome matrix protein import, translocation|protein translocation during protein import into peroxisome matrix|protein translocation during peroxisome matrix protein import|protein translocation during protein transport into peroxisome matrix|peroxisome receptor translocation|protein transport into peroxisome matrix, translocation													biological_process											owl:Class	
GO:0065002	biolink:NamedThing	intracellular protein transmembrane transport	The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.	got7fsn_ti	intracellular protein membrane transport|intracellular membrane translocation of a protein|intracellular protein transport across a membrane				Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:0002684	biolink:NamedThing	positive regulation of immune system process	Any process that activates or increases the frequency, rate, or extent of an immune system process.	got7fsn_ti	up-regulation of immune system process|upregulation of immune system process|up regulation of immune system process|stimulation of immune system process|activation of immune system process													biological_process											owl:Class	
GO:0042608	biolink:NamedThing	T cell receptor binding	Binding to a T cell receptor, the antigen-recognizing receptor on the surface of T cells.	got7fsn_ti	T-lymphocyte receptor binding|T-cell receptor binding|TCR binding|T lymphocyte receptor binding													molecular_function											owl:Class	
GO:0004692	biolink:NamedThing	cGMP-dependent protein kinase activity	cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	got7fsn_ti	STK23|ATP:protein phosphotransferase (cGMP-dependent) activity|PKG|guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity|PKG 1alpha|PKG II|PKG 1beta|cGMP-dependent protein kinase ibeta activity|3':5'-cyclic GMP-dependent protein kinase activity				This reaction requires the presence of cGMP.							Reactome:R-HSA-418549|MetaCyc:2.7.11.12-RXN|Reactome:R-HSA-418442|EC:2.7.11.12|Reactome:R-HSA-1475422|Reactome:R-HSA-1497853		molecular_function											owl:Class	
GO:0039545	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses.	got7fsn_ti	suppression by virus of host mitochondrial antiviral-signaling protein|suppression by virus of host MAVS activity|inhibition of host MAVS by virus	https://github.com/geneontology/go-ontology/issues/21983			This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-01-19T02:37:20Z						biological_process											owl:Class	
GO:0060748	biolink:NamedThing	tertiary branching involved in mammary gland duct morphogenesis	The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.	got7fsn_ti							dph	2009-06-22T10:44:51Z						biological_process											owl:Class	
GO:1990043	biolink:NamedThing	5' deoxyribonuclease (pyrimidine dimer) activity	Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate.	got7fsn_ti							pr	2013-02-15T12:16:51Z						molecular_function											owl:Class	
GO:0033892	biolink:NamedThing	deoxyribonuclease (pyrimidine dimer) activity	Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate.	got7fsn_ti	bacteriophage T4 endodeoxyribonuclease V activity|endodeoxyribonuclease (pyrimidine dimer) activity|T4 endonuclease V activity											MetaCyc:3.1.25.1-RXN|EC:3.1.25.1		molecular_function											owl:Class	
GO:1905331	biolink:NamedThing	negative regulation of morphogenesis of an epithelium	Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium.	got7fsn_ti	inhibition of morphogenesis of an epithelium|down regulation of morphogenesis of an epithelium|inhibition of epithelium morphogenesis|down-regulation of morphogenesis of an epithelium|negative regulation of epithelium morphogenesis|down regulation of epithelium morphogenesis|downregulation of morphogenesis of an epithelium|downregulation of epithelium morphogenesis|down-regulation of epithelium morphogenesis				An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-07-22T07:13:57Z						biological_process											owl:Class	
GO:0035225	biolink:NamedThing	determination of genital disc primordium	Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two.	got7fsn_ti														biological_process											owl:Class	
GO:0034938	biolink:NamedThing	pyrrole-2-carboxylate monooxygenase activity	Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O.	got7fsn_ti												EC:1.14.14.-|UM-BBD_reactionID:r0968		molecular_function											owl:Class	
GO:0047400	biolink:NamedThing	phosphonoacetate hydrolase activity	Catalysis of the reaction: H(2)O + phosphonoacetate = acetate + H(+) + phosphate.	got7fsn_ti	phosphonoacetate phosphonohydrolase activity											EC:3.11.1.2|MetaCyc:3.11.1.2-RXN|RHEA:16749|KEGG_REACTION:R00318		molecular_function											owl:Class	
GO:0016827	biolink:NamedThing	hydrolase activity, acting on acid carbon-phosphorus bonds	Catalysis of the hydrolysis of any acid carbon-phosphorus bond.	got7fsn_ti												EC:3.11.-.-		molecular_function											owl:Class	
GO:0048650	biolink:NamedThing	caste determination, influence by environmental factors	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.	got7fsn_ti														biological_process											owl:Class	
GO:0034626	biolink:NamedThing	fatty acid elongation, polyunsaturated fatty acid	Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced.	got7fsn_ti														biological_process											owl:Class	
GO:0019368	biolink:NamedThing	fatty acid elongation, unsaturated fatty acid	Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced.	got7fsn_ti												MetaCyc:PWY0-862		biological_process											owl:Class	
GO:0021619	biolink:NamedThing	hypoglossal nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	got7fsn_ti	CN XII maturation													biological_process											owl:Class	
GO:0006544	biolink:NamedThing	glycine metabolic process	The chemical reactions and pathways involving glycine, aminoethanoic acid.	got7fsn_ti	glycine metabolism													biological_process											owl:Class	
GO:0052894	biolink:NamedThing	norspermine:oxygen oxidoreductase activity	Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide.	got7fsn_ti	norspermine oxidase activity											MetaCyc:RXN-10464|EC:1.5.3.16		molecular_function											owl:Class	
GO:0051668	biolink:NamedThing	localization within membrane	Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.	got7fsn_ti	establishment and maintenance of localization in membrane|positioning within membrane|establishment and maintenance of position in membrane|localisation within membrane|localization to membrane													biological_process											owl:Class	
GO:0102924	biolink:NamedThing	gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: 2 H+ + gibberellin A44 + 2-oxoglutarate + O2 = gibberellin A98 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-886		molecular_function											owl:Class	
GO:0052163	biolink:NamedThing	symbiont defense to host-produced nitric oxide	Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	evasion or tolerance by organism of host NO|defense response to host innate immune response nitric oxide production|response to defense-related nitric oxide production by other organism involved in symbiotic interaction|evasion or tolerance by organism of host nitric oxide|modulation by organism of defense-related host NO production|evasion or tolerance of NO produced by host in response to organism|evasion or tolerance by organism of nitric oxide produced by other organism involved in symbiotic interaction|modulation by symbiont of defense-related host nitric oxide production|modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|evasion or tolerance by organism of host-produced NO|evasion or tolerance by organism of host-produced nitric oxide|evasion or tolerance by symbiont of host-produced nitric oxide|response to defense-related host nitric oxide production|evasion or tolerance of nitric oxide produced by host in response to organism	https://github.com/geneontology/go-ontology/issues/18798									GO:0052376|GO:0052060|GO:0052302|GO:0052565|GO:0052551			biological_process											owl:Class	
GO:0048774	biolink:NamedThing	cyanophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes.	got7fsn_ti	cyanophore cell differentiation													biological_process											owl:Class	
GO:0018648	biolink:NamedThing	methanesulfonate monooxygenase activity	Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O.	got7fsn_ti	methanesulfonate,NADH:oxygen oxidoreductase activity|mesylate monooxygenase activity|methanesulphonic acid monooxygenase activity|methanesulfonic acid monooxygenase activity|methanesulfonate,FMNH2:oxygen oxidoreductase activity|MSA monooxygenase activity|MSAMO activity											RHEA:26077|EC:1.14.13.111|MetaCyc:RXN-9770		molecular_function											owl:Class	
GO:0070828	biolink:NamedThing	heterochromatin organization	Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.	got7fsn_ti	heterochromatin organisation						mah	2009-07-23T04:12:48Z						biological_process											owl:Class	
GO:0048706	biolink:NamedThing	embryonic skeletal system development	The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.	got7fsn_ti	embryonic skeletal development													biological_process											owl:Class	
GO:1990213	biolink:NamedThing	negative regulation by symbiont of salicylic acid levels in host	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-09T19:06:19Z						biological_process											owl:Class	
GO:0052150	biolink:NamedThing	modulation by symbiont of host apoptotic process	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host apoptosis|modulation by organism of host apoptotic programmed cell death				Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'regulation of apoptosis ; GO:0042981'.									biological_process											owl:Class	
GO:0051709	biolink:NamedThing	regulation of killing of cells of other organism	Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism.	got7fsn_ti	modulation by organism of apoptotic process in other organism involved in symbiotic interaction|regulation of killing of cells of another organism|modulation of programmed cell death in other organism involved in symbiotic interaction|modulation of programmed cell death in other organism	https://github.com/geneontology/go-ontology/issues/20287					jl	2012-03-20T04:48:41Z			GO:0052248|GO:0044531|GO:0052459|GO:0052433			biological_process											owl:Class	
GO:0140108	biolink:NamedThing	high-affinity glucose transmembrane transporter activity	Enables the transfer of glucose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14212					pg	2017-10-12T10:06:19Z						molecular_function											owl:Class	
GO:0005355	biolink:NamedThing	glucose transmembrane transporter activity	Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.	got7fsn_ti	lactose/glucose efflux transporter activity|glucose permease activity|galactose/glucose (methylgalactoside) porter activity										GO:0015579	Reactome:R-HSA-5653873|Reactome:R-HSA-499981		molecular_function											owl:Class	
GO:0033552	biolink:NamedThing	response to vitamin B3	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.	got7fsn_ti	response to nicotinamide|response to niacin													biological_process											owl:Class	
GO:0038009	biolink:NamedThing	regulation of signal transduction by receptor internalization	Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway.	got7fsn_ti	regulation of signaling pathway by receptor endocytosis						bf	2011-06-23T03:28:47Z						biological_process											owl:Class	
GO:0086070	biolink:NamedThing	SA node cell to atrial cardiac muscle cell communication	The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti	sinus node cardiomyocyte to atrial cardiomyocyte communication|sinoatrial node cardiomyocyte to atrial cardiomyocyte communication|SA node cardiac muscle cell to atrial cardiac muscle cell communication|SAN cardiomyocyte to atrial cardiomyocyte communication|SA node cardiomyocyte to atrial cardiomyocyte communication						dph	2011-11-22T09:32:45Z						biological_process											owl:Class	
GO:0086065	biolink:NamedThing	cell communication involved in cardiac conduction	Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti							dph	2011-11-22T08:57:02Z						biological_process											owl:Class	
GO:0031160	biolink:NamedThing	spore wall	The specialized envelope lying outside the cell membrane of a spore.	got7fsn_ti	spore coat													cellular_component											owl:Class	
GO:0000467	biolink:NamedThing	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0000459	biolink:NamedThing	exonucleolytic trimming involved in rRNA processing	Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule.	got7fsn_ti	exonucleolytic trimming during rRNA processing													biological_process											owl:Class	
GO:0044643	biolink:NamedThing	envenomation resulting in positive regulation of complement activation, alternative pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism.	got7fsn_ti							jl	2012-07-11T11:56:48Z						biological_process											owl:Class	
GO:0044642	biolink:NamedThing	envenomation resulting in modulation of complement activation, alternative pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism.	got7fsn_ti	envenomation resulting in regulation of complement activation, alternative pathway in other organism						jl	2012-07-11T11:53:12Z						biological_process											owl:Class	
GO:0031653	biolink:NamedThing	heat dissipation	Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.	got7fsn_ti														biological_process											owl:Class	
GO:0050429	biolink:NamedThing	calcium-dependent phospholipase C activity	Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+.	got7fsn_ti														molecular_function											owl:Class	
GO:0021983	biolink:NamedThing	pituitary gland development	The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.	got7fsn_ti	hypophysis development													biological_process											owl:Class	
GO:0031256	biolink:NamedThing	leading edge membrane	The portion of the plasma membrane surrounding the leading edge of a motile cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0018186	biolink:NamedThing	peroxidase-heme linkage	The covalent linkage of heme to peroxidase.	got7fsn_ti	peroxidase-haem linkage											RESID:AA0280|RESID:AA0279		biological_process											owl:Class	
GO:0040035	biolink:NamedThing	hermaphrodite genitalia development	The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures.	got7fsn_ti														biological_process											owl:Class	
GO:0060512	biolink:NamedThing	prostate gland morphogenesis	The process in which the anatomical structures of a prostate gland are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0006402	biolink:NamedThing	mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.	got7fsn_ti	mRNA catabolism|mRNA breakdown|mRNA degradation|mRNA decay													biological_process											owl:Class	
GO:0002123	biolink:NamedThing	irritable aggressive behavior	Aggressive behavior induced by frustration and directed against an available target.	got7fsn_ti	irritable aggression													biological_process											owl:Class	
GO:0061705	biolink:NamedThing	sucrose catabolic process to fructose-6-phosphate through glucose and fructose	The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates.	got7fsn_ti							dph	2015-06-11T13:32:05Z				MetaCyc:PWY-621		biological_process											owl:Class	
GO:0005987	biolink:NamedThing	sucrose catabolic process	The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.	got7fsn_ti	sucrose catabolism|sucrose breakdown|sucrose degradation													biological_process											owl:Class	
GO:0060404	biolink:NamedThing	axonemal microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.	got7fsn_ti														biological_process											owl:Class	
GO:0140028	biolink:NamedThing	pore formation during contractile vacuole discharge	The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes.	got7fsn_ti							pg	2017-05-15T12:20:27Z						biological_process											owl:Class	
GO:0140029	biolink:NamedThing	exocytic process	The cellular processes that contribute to exocytosis.	got7fsn_ti							pg	2017-05-15T13:20:45Z						biological_process											owl:Class	
GO:0018586	biolink:NamedThing	mono-butyltin dioxygenase activity	Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin.	got7fsn_ti	MBT dioxygenase activity											UM-BBD_reactionID:r0647		molecular_function											owl:Class	
GO:0002211	biolink:NamedThing	behavioral defense response to insect	A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.	got7fsn_ti	behavioural defense response to insect													biological_process											owl:Class	
GO:0033901	biolink:NamedThing	ribonuclease V activity	Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP.	got7fsn_ti	endoribonuclease V activity											MetaCyc:3.1.27.8-RXN|EC:3.1.27.8		molecular_function											owl:Class	
GO:0016892	biolink:NamedThing	endoribonuclease activity, producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.	got7fsn_ti	endoribonuclease activity, producing other than 5'-phosphomonoesters											EC:3.1.27.-		molecular_function											owl:Class	
GO:0021799	biolink:NamedThing	cerebral cortex radially oriented cell migration	The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.	got7fsn_ti														biological_process											owl:Class	
GO:0033858	biolink:NamedThing	N-acetylgalactosamine kinase activity	Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.	got7fsn_ti	GK2|GALK2|GalNAc kinase activity|ATP:N-acetyl-D-galactosamine 1-phosphotransferase activity|N-acetylgalactosamine (GalNAc)-1-phosphate kinase activity											RHEA:12617|EC:2.7.1.157|MetaCyc:2.7.1.157-RXN		molecular_function											owl:Class	
GO:0035512	biolink:NamedThing	hydrolytic DNA demethylation	The hydrolytic removal of the methyl group from one or more nucleotides within a DNA molecule.	got7fsn_ti							bf	2010-04-30T02:24:21Z						biological_process											owl:Class	
GO:0080111	biolink:NamedThing	DNA demethylation	The removal of a methyl group from one or more nucleotides within an DNA molecule.	got7fsn_ti							dhl	2009-04-27T02:42:05Z						biological_process											owl:Class	
GO:0050746	biolink:NamedThing	regulation of lipoprotein metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	got7fsn_ti	regulation of lipoprotein metabolism													biological_process											owl:Class	
GO:0000277	biolink:NamedThing	[cytochrome c]-lysine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c.	got7fsn_ti	S-adenosyl-L-methionine:cytochrome c-L-lysine N6-methyltransferase activity|cytochrome c-specific protein methylase III activity|cytochrome c methyltransferase activity|cytochrome c-specific protein-lysine methyltransferase activity|cytochrome c (lysine) methyltransferase activity|cytochrome c-lysine N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-L-lysine 6-N-methyltransferase activity											RHEA:24312|EC:2.1.1.59|MetaCyc:2.1.1.59-RXN		molecular_function											owl:Class	
GO:0044161	biolink:NamedThing	host cell cytoplasmic vesicle	A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.	got7fsn_ti							jl	2009-08-11T04:22:21Z						cellular_component											owl:Class	
GO:0036407	biolink:NamedThing	mycolate outer membrane	A mycolic acid-rich cell outer membrane containing a lipid bilayer and long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. Found in mycobacteria and related genera (e.g. corynebacteria).	got7fsn_ti	mycomembrane|mycolate outer membrane|MOM|mycobacterial outer membrane						bf	2013-08-15T13:33:46Z						cellular_component											owl:Class	
GO:0009279	biolink:NamedThing	cell outer membrane	A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.	got7fsn_ti	outer membrane of cell				To annotate the plasma (cytoplasmic) membrane, see instead GO:0005886.									cellular_component											owl:Class	
GO:0033380	biolink:NamedThing	granzyme B localization to T cell secretory granule	Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.	got7fsn_ti	granzyme B localization in T cell secretory granule|granzyme B localization in T-lymphocyte secretory granule|granzyme B localization in T lymphocyte secretory granule|granzyme B localisation in T cell secretory granule|granzyme B localization in T-cell secretory granule													biological_process											owl:Class	
GO:0033375	biolink:NamedThing	protease localization to T cell secretory granule	Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell.	got7fsn_ti	protease localization in T-lymphocyte secretory granule|protease localization in T-cell secretory granule|protease localisation in T cell secretory granule|protease localization in T lymphocyte secretory granule|protease localization in T cell secretory granule													biological_process											owl:Class	
GO:1901657	biolink:NamedThing	glycosyl compound metabolic process	The chemical reactions and pathways involving glycosyl compound.	got7fsn_ti	glycosyl compound metabolism						pr	2012-11-20T14:24:07Z						biological_process											owl:Class	
GO:0044478	biolink:NamedThing	envenomation resulting in positive regulation of platelet aggregation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:39:45Z						biological_process											owl:Class	
GO:0044469	biolink:NamedThing	envenomation resulting in positive regulation of blood coagulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism.	got7fsn_ti							jl	2012-01-19T01:29:09Z						biological_process											owl:Class	
GO:1990038	biolink:NamedThing	Lewy body corona	The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.	got7fsn_ti	halo						pr	2013-02-08T13:03:27Z				NIF_Subcellular:sao5764355747		cellular_component											owl:Class	
GO:0106363	biolink:NamedThing	protein-cysteine methyltransferase activity	Catalysis of the reaction: L-cysteinyl-[protein] + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein].	got7fsn_ti							hjd	2021-02-05T15:44:58Z				RHEA:66544		molecular_function											owl:Class	
GO:0044307	biolink:NamedThing	dendritic branch	A dendrite arising from another dendrite.	got7fsn_ti	dendrite branch|secondary dendrite						jl	2010-02-05T04:18:53Z				NIF_Subcellular:sao884265541		cellular_component											owl:Class	
GO:0006360	biolink:NamedThing	transcription by RNA polymerase I	The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.	got7fsn_ti	transcription from RNA polymerase I promoter|transcription from Pol I promoter|RNA polymerase I transcription factor activity	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0009819	biolink:NamedThing	drought recovery	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.	got7fsn_ti	drought tolerance													biological_process											owl:Class	
GO:0018640	biolink:NamedThing	dibenzothiophene monooxygenase activity	Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O.	got7fsn_ti												RHEA:49076|UM-BBD_enzymeID:e0214|MetaCyc:RXN-621		molecular_function											owl:Class	
GO:1903523	biolink:NamedThing	negative regulation of blood circulation	Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.	got7fsn_ti	down regulation of hemolymph circulation|negative regulation of hemolymph circulation|down-regulation of hemolymph circulation|inhibition of hemolymph circulation|inhibition of blood circulation|down-regulation of blood circulation|down regulation of blood circulation|downregulation of blood circulation|downregulation of hemolymph circulation						mr	2014-10-06T18:39:05Z						biological_process											owl:Class	
GO:0002755	biolink:NamedThing	MyD88-dependent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	got7fsn_ti	MyD88-dependent toll-like receptor signalling pathway|MyD88-dependent TLR signaling pathway													biological_process											owl:Class	
GO:0046676	biolink:NamedThing	negative regulation of insulin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.	got7fsn_ti	down regulation of insulin secretion|downregulation of insulin secretion|down-regulation of insulin secretion|inhibition of insulin secretion													biological_process											owl:Class	
GO:0009824	biolink:NamedThing	AMP dimethylallyltransferase activity	Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate.	got7fsn_ti	adenylate dimethylallyltransferase activity|isopentenyltransferase activity|2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase activity|dimethylallyl-diphosphate:AMP dimethylallyltransferase activity|adenylate isopentenyltransferase activity|cytokinin synthase activity|2-isopentenyl-diphosphate:AMP 2-isopentenyltransferase activity											MetaCyc:RXN-4307|RHEA:15285|EC:2.5.1.27|KEGG_REACTION:R04038		molecular_function											owl:Class	
GO:0019772	biolink:NamedThing	low-affinity IgG receptor activity	Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	low affinity Fc receptor activity|low affinity IgG receptor activity													molecular_function											owl:Class	
GO:0009251	biolink:NamedThing	glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues.	got7fsn_ti	glucan breakdown|glucan catabolism|glucan degradation													biological_process											owl:Class	
GO:0000272	biolink:NamedThing	polysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	got7fsn_ti	polysaccharide breakdown|multicellular organismal polysaccharide catabolic process|polysaccharide catabolism|polysaccharide degradation										GO:0044244			biological_process											owl:Class	
GO:0047071	biolink:NamedThing	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H(+).	got7fsn_ti	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing)|3-alkylcatechol 2,3-dioxygenase activity|steroid 4,5-dioxygenase activity											EC:1.13.11.25|RHEA:21352|UM-BBD_reactionID:r1151|MetaCyc:1.13.11.25-RXN|KEGG_REACTION:R04597		molecular_function											owl:Class	
GO:0060116	biolink:NamedThing	vestibular receptor cell morphogenesis	Any process that alters the size or shape of a vestibular receptor cell.	got7fsn_ti	vestibular hair cell morphogenesis													biological_process											owl:Class	
GO:0043685	biolink:NamedThing	conversion of glutamyl-tRNA to glutaminyl-tRNA	The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA.	got7fsn_ti					Note that this process has been observed in some archaeal and bacterial species.									biological_process											owl:Class	
GO:0070744	biolink:NamedThing	interleukin-27 complex	A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.	got7fsn_ti	IL-27 complex|p28|EBI3|IL27				Note that this heterodimeric cytokine utilizes the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-35 uses for its beta chain. Also note that the product of the IL27 gene is the alpha subunit of IL-27. The functional IL-27 protein complex requires both subunits.		mah	2009-06-23T01:09:58Z						cellular_component											owl:Class	
GO:0018897	biolink:NamedThing	dibenzothiophene desulfurization	The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.	got7fsn_ti	dibenzothiophene desulphurization											UM-BBD_pathwayID:dbt|MetaCyc:PWY-681		biological_process											owl:Class	
GO:0018895	biolink:NamedThing	dibenzothiophene metabolic process	The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion.	got7fsn_ti	diphenylene sulfide metabolic process|diphenylene sulfide metabolism|dibenzothiophene metabolism													biological_process											owl:Class	
GO:0061631	biolink:NamedThing	ubiquitin conjugating enzyme activity	Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2|HECT E3						dph	2014-05-18T09:25:19Z				EC:2.3.2.23		molecular_function											owl:Class	
GO:0014849	biolink:NamedThing	ureter smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.	got7fsn_ti														biological_process											owl:Class	
GO:0008898	biolink:NamedThing	S-adenosylmethionine-homocysteine S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine.	got7fsn_ti	S-adenosylmethionine:homocysteine methyltransferase activity|S-adenosyl-L-methionine:L-homocysteine S-methyltransferase activity|adenosylmethionine:homocysteine methyltransferase activity|S-adenosylmethionine-homocysteine transmethylase activity|adenosylmethionine transmethylase activity|L-homocysteine S-methyltransferase activity|homocysteine methyltransferase activity|S-adenosylmethionine homocysteine transmethylase activity|homocysteine transmethylase activity|S-adenosyl-L-methionine:L-homocysteine methyltransferase activity											RHEA:21820|MetaCyc:HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0019921	biolink:NamedThing	peptidyl-1-thioglycine biosynthetic process, carboxy-terminal	The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond.	got7fsn_ti	peptidyl-1-thioglycine formation, carboxy-terminal|peptidyl-1-thioglycine synthesis, carboxy-terminal|peptidyl-1-thioglycine anabolism, carboxy-terminal											RESID:AA0265		biological_process											owl:Class	
GO:0034001	biolink:NamedThing	chondroitin-sulfate-ABC exolyase activity	Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments.	got7fsn_ti	chondroitin ABC eliminase activity|chondroitin sulfate ABC exoeliminase activity|ChS ABC lyase activity|ChS ABC lyase II activity|chondroitin sulfate ABC exolyase activity|chondroitinase ABC activity|chondroitinase activity|chondroitin sulfate ABC lyase activity											MetaCyc:4.2.2.21-RXN|EC:4.2.2.21		molecular_function											owl:Class	
GO:0047486	biolink:NamedThing	chondroitin ABC lyase activity	Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.	got7fsn_ti														molecular_function											owl:Class	
GO:0035187	biolink:NamedThing	hatching behavior	The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.	got7fsn_ti	hatching behaviour													biological_process											owl:Class	
GO:0033606	biolink:NamedThing	chemokine receptor transport within lipid bilayer	The directed movement of a chemokine receptor within a lipid bilayer.	got7fsn_ti	chemokine receptor translocation within membrane													biological_process											owl:Class	
GO:0097721	biolink:NamedThing	ciliary vesicle	A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle.	got7fsn_ti	CV|primary ciliary vesicle						pr	2016-08-30T13:54:38Z						cellular_component											owl:Class	
GO:0061374	biolink:NamedThing	mammillothalamic axonal tract development	The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.	got7fsn_ti							dph	2010-11-09T08:54:43Z						biological_process											owl:Class	
GO:0044781	biolink:NamedThing	bacterial-type flagellum organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.	got7fsn_ti							jl	2013-03-27T15:07:00Z						biological_process											owl:Class	
GO:0031993	biolink:NamedThing	light transducer activity	Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.	got7fsn_ti														molecular_function											owl:Class	
GO:0031992	biolink:NamedThing	energy transducer activity	The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.	got7fsn_ti	photon capture|light harvesting activity													molecular_function											owl:Class	
GO:0039587	biolink:NamedThing	suppression by virus of host tetherin activity	Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects.	got7fsn_ti	inhibition of host BST2/Tetherin by virus|suppression by virus of host BST-2 activity						bf	2012-05-04T02:33:29Z				VZ:665		biological_process											owl:Class	
GO:0039506	biolink:NamedThing	modulation by virus of host molecular function	The process in which a virus effects a change in the function of a host protein via a direct interaction.	got7fsn_ti	modification by virus of host protein function						bf	2011-06-02T02:38:42Z						biological_process											owl:Class	
GO:0005200	biolink:NamedThing	structural constituent of cytoskeleton	The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.	got7fsn_ti														molecular_function											owl:Class	
GO:0030762	biolink:NamedThing	tetrahydrocolumbamine 2-O-methyltransferase activity	Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine.	got7fsn_ti	tetrahydrocolumbamine methyltransferase activity|S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase activity											MetaCyc:2.1.1.89-RXN|RHEA:22536|KEGG_REACTION:R04077|EC:2.1.1.89		molecular_function											owl:Class	
GO:0030267	biolink:NamedThing	glyoxylate reductase (NADP+) activity	Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.	got7fsn_ti	glyoxylate reductase (NADP+)|NADPH-glyoxylate reductase activity|glycolate:NADP+ oxidoreductase activity											RHEA:10992|Reactome:R-HSA-389826|Wikipedia:Glyoxylate_reductase_(NADP+)|MetaCyc:GLYOXYLATE-REDUCTASE-NADP+-RXN|EC:1.1.1.79		molecular_function											owl:Class	
GO:0106345	biolink:NamedThing	glyoxylate reductase activity	Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H.	got7fsn_ti							hjd	2020-12-08T14:14:31Z						molecular_function											owl:Class	
GO:0045852	biolink:NamedThing	pH elevation	Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.	got7fsn_ti														biological_process											owl:Class	
GO:0006885	biolink:NamedThing	regulation of pH	Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.	got7fsn_ti	hydrogen ion homeostasis													biological_process											owl:Class	
GO:0030241	biolink:NamedThing	skeletal muscle myosin thick filament assembly	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle.	got7fsn_ti														biological_process											owl:Class	
GO:0071688	biolink:NamedThing	striated muscle myosin thick filament assembly	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle.	got7fsn_ti							mah	2010-02-25T03:52:21Z						biological_process											owl:Class	
GO:0032019	biolink:NamedThing	mitochondrial cloud	A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.	got7fsn_ti	Balbiani body|mitochondrial aggregate													cellular_component											owl:Class	
GO:0039574	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK1-STAT signaling cascade in a host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits.	got7fsn_ti	suppression by virus of host TYK2 activity|suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity	https://github.com/geneontology/go-ontology/issues/21986					bf							biological_process											owl:Class	
GO:0039514	biolink:NamedThing	suppression by virus of host JAK-STAT cascade	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the JAK-STAT signal cascade in the host organism.	got7fsn_ti	down-regulation by virus of host JAK-STAT cascade|inhibition by virus of host JAK-STAT cascade|negative regulation by virus of host JAK-STAT cascade|downregulation by virus of host JAK-STAT cascade						bf	2011-06-16T02:48:03Z						biological_process											owl:Class	
GO:0050326	biolink:NamedThing	taxifolin 8-monooxygenase activity	Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O.	got7fsn_ti	taxifolin hydroxylase activity|taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating)											EC:1.14.13.19|MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0031942	biolink:NamedThing	i-AAA complex	Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.	got7fsn_ti														cellular_component											owl:Class	
GO:0010338	biolink:NamedThing	leaf formation	The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti														biological_process											owl:Class	
GO:0099402	biolink:NamedThing	plant organ development	Development of a plant organ, a multi-tissue plant structure that forms a functional unit.	got7fsn_ti	development of a plant organ													biological_process											owl:Class	
GO:0008412	biolink:NamedThing	4-hydroxybenzoate octaprenyltransferase activity	Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.	got7fsn_ti	4-HB polyprenyltransferase activity|para-hydroxybenzoate:polyprenyltransferase activity|para-hydroxybenzoate transferase activity|PHB polyprenyl diphosphate transferase activity|para-hydroxybenzoate-polyprenyl diphosphate transferase activity										GO:0048044|GO:0000043|GO:0048043	EC:2.5.1.39|MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN|RHEA:27782		molecular_function											owl:Class	
GO:0021749	biolink:NamedThing	ventral cochlear nucleus development	The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0042424	biolink:NamedThing	catecholamine catabolic process	The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	got7fsn_ti	catecholamine degradation|catecholamine catabolism|catecholamine breakdown													biological_process											owl:Class	
GO:0090531	biolink:NamedThing	L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose	The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose.	got7fsn_ti	L-ascorbic acid biosynthesis via GDP-alpha-D-mannose|Smirnoff-Wheeler's pathway						tb	2013-02-06T15:31:01Z				BioCyc:PWY-882		biological_process											owl:Class	
GO:0042733	biolink:NamedThing	embryonic digit morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.	got7fsn_ti														biological_process											owl:Class	
GO:0070532	biolink:NamedThing	BRCA1-B complex	A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.	got7fsn_ti														cellular_component											owl:Class	
GO:0021973	biolink:NamedThing	corticospinal neuron axon decussation	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.	got7fsn_ti														biological_process											owl:Class	
GO:0016199	biolink:NamedThing	axon midline choice point recognition	The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.	got7fsn_ti														biological_process											owl:Class	
GO:0097124	biolink:NamedThing	cyclin A2-CDK2 complex	A protein complex consisting of cyclin A2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:44:19Z						cellular_component											owl:Class	
GO:0008022	biolink:NamedThing	protein C-terminus binding	Binding to a protein C-terminus, the end of a peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.	got7fsn_ti	carboxy-terminus binding|carboxyl-terminus binding|COOH-terminus binding|C-terminal end binding|COOH-terminal binding|C-terminal binding|carboxy-terminal binding|carboxylate-terminus binding|carboxyl-terminal binding|carboxylate-terminal binding													molecular_function											owl:Class	
GO:1990469	biolink:NamedThing	Rhino-Deadlock-Cutoff Complex	Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation.	got7fsn_ti	RDC complex|rhi-del-cuff complex				An example of this is cuff in Drosophila melanogaster (Q9V629) in PMID:24906153.		bhm	2014-08-29T14:08:37Z						cellular_component											owl:Class	
GO:0046806	biolink:NamedThing	viral scaffold	A complex of proteins that form a scaffold around which the viral capsid is constructed.	got7fsn_ti														cellular_component											owl:Class	
GO:0034038	biolink:NamedThing	deoxyhypusine synthase activity	Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+.	got7fsn_ti	eIF5A-precursor-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity|spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity|eIF-5A-deoxyhypusine synthase activity				Note that this term is equivalent to the obsolete molecular function term 'deoxyhypusine synthase activity ; GO:0004171' and corresponds closely to the biological process term 'deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase ; GO:0050983'.							Reactome:R-HSA-204617|MetaCyc:2.5.1.46-RXN|EC:2.5.1.46|Reactome:R-HSA-204647|RHEA:33299		molecular_function											owl:Class	
GO:0097468	biolink:NamedThing	programmed cell death in response to reactive oxygen species	Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	got7fsn_ti	reactive oxygen species-mediated programmed cell death|PCD in response to reactive oxygen species|reactive oxygen species-mediated PCD|programmed cell death in response to oxidative stress|PCD in response to oxidative stress						pr	2013-02-19T10:03:36Z						biological_process											owl:Class	
GO:0042752	biolink:NamedThing	regulation of circadian rhythm	Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.	got7fsn_ti														biological_process											owl:Class	
GO:0052627	biolink:NamedThing	vanillate amino acid synthetase activity	Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0060614	biolink:NamedThing	negative regulation of mammary gland development in males by androgen receptor signaling pathway	Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell.	got7fsn_ti	negative regulation of mammary gland development in males by androgen receptor signalling pathway						dph	2009-05-18T08:34:40Z						biological_process											owl:Class	
GO:1990790	biolink:NamedThing	response to glial cell derived neurotrophic factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.	got7fsn_ti	response to ATF|response to GDNF|response to astrocyte-derived trophic factor						sl	2015-07-02T19:47:05Z						biological_process											owl:Class	
GO:0070343	biolink:NamedThing	white fat cell proliferation	The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.	got7fsn_ti	white adipose cell proliferation|white adipocyte proliferation													biological_process											owl:Class	
GO:0022853	biolink:NamedThing	active ion transmembrane transporter activity	Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.	got7fsn_ti														molecular_function											owl:Class	
GO:0015075	biolink:NamedThing	ion transmembrane transporter activity	Enables the transfer of an ion from one side of a membrane to the other.	got7fsn_ti	ion transporter activity													molecular_function											owl:Class	
GO:0018864	biolink:NamedThing	acetylene metabolic process	The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes.	got7fsn_ti	acetylene metabolism|ethyne metabolic process|ethyne metabolism											UM-BBD_pathwayID:atl		biological_process											owl:Class	
GO:0003313	biolink:NamedThing	heart rudiment development	The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.	got7fsn_ti	heart cone development						dph	2009-10-27T08:32:40Z						biological_process											owl:Class	
GO:0033102	biolink:NamedThing	acidocalcisome membrane	The lipid bilayer surrounding an acidocalcisome.	got7fsn_ti														cellular_component											owl:Class	
GO:1990942	biolink:NamedThing	mitotic metaphase chromosome recapture	A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate.	got7fsn_ti	microtubule sliding involved in sister kinetochore recapture|kinetochore retrieval|microtubule sliding involved in mitotic metaphase chromosome recapture|sister kinetochore recapture|metaphase chromosome retrieval to the spindle pole body|microtubule sliding involved in metaphase chromosome retrieval to the spindle pole body|microtubule sliding involved in kinetochore retrieval						vw	2016-04-06T14:41:56Z			GO:1905185			biological_process											owl:Class	
GO:0042020	biolink:NamedThing	interleukin-23 receptor activity	Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-23 receptor activity|IL-23R													molecular_function											owl:Class	
GO:0018613	biolink:NamedThing	9-fluorenone dioxygenase activity	Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone.	got7fsn_ti												EC:1.14.12.-|UM-BBD_reactionID:r0409		molecular_function											owl:Class	
GO:0080147	biolink:NamedThing	root hair cell development	The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state.	got7fsn_ti							dhl	2010-03-26T01:45:08Z						biological_process											owl:Class	
GO:0010544	biolink:NamedThing	negative regulation of platelet activation	Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0097589	biolink:NamedThing	archaeal-type flagellum	A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function.	got7fsn_ti	archaella|archaellum|archaeal flagellum						pr	2014-03-25T20:36:24Z						cellular_component											owl:Class	
GO:0060611	biolink:NamedThing	mammary gland fat development	The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.	got7fsn_ti							dph	2009-05-15T12:27:57Z						biological_process											owl:Class	
GO:0047660	biolink:NamedThing	amidinoaspartase activity	Catalysis of the reaction: N-amidino-L-aspartate + H(2)O = L-aspartate + urea.	got7fsn_ti	N-amidino-L-aspartate amidinohydrolase activity|amidinoaspartic amidinohydrolase activity											MetaCyc:AMIDINOASPARTASE-RXN|KEGG_REACTION:R00777|RHEA:14849|EC:3.5.3.14		molecular_function											owl:Class	
GO:0030650	biolink:NamedThing	peptide antibiotic metabolic process	The chemical reactions and pathways involving peptides with antibiotic activity.	got7fsn_ti	peptide antibiotic metabolism													biological_process											owl:Class	
GO:0034020	biolink:NamedThing	neoxanthin synthase activity	Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin.	got7fsn_ti	violaxanthin-neoxanthin isomerase (epoxide-opening) activity|NSY											KEGG_REACTION:R06948|RHEA:10128|EC:5.3.99.9|MetaCyc:RXN1F-155		molecular_function											owl:Class	
GO:0035261	biolink:NamedThing	external genitalia morphogenesis	The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.	got7fsn_ti														biological_process											owl:Class	
GO:0035112	biolink:NamedThing	genitalia morphogenesis	The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.	got7fsn_ti	genital morphogenesis													biological_process											owl:Class	
GO:0035590	biolink:NamedThing	purinergic nucleotide receptor signaling pathway	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity.	got7fsn_ti	P2 receptor signaling pathway|purinergic receptor signaling pathway|purinergic nucleotide receptor signalling pathway|purinoceptor signaling pathway|purinergic receptor signalling pathway						bf	2010-10-22T11:09:40Z			GO:0035587			biological_process											owl:Class	
GO:0005984	biolink:NamedThing	disaccharide metabolic process	The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units.	got7fsn_ti	disaccharide metabolism													biological_process											owl:Class	
GO:0070422	biolink:NamedThing	G-protein beta/gamma-Raf-1 complex	A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein.	got7fsn_ti	G protein complex (GNG2, GNB2L1, RAF1)				See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'.									cellular_component											owl:Class	
GO:0003415	biolink:NamedThing	chondrocyte hypertrophy	The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time.	got7fsn_ti							dph	2009-12-22T08:48:44Z						biological_process											owl:Class	
GO:0003374	biolink:NamedThing	dynamin family protein polymerization involved in mitochondrial fission	The process of creating dynamin protein family polymers, compounds composed of a large number of dynamin family monomers around a lipid tube of a dividing mitochondrion. Dynamin polymers form around lipid tubes and contribute to membrane fission.	got7fsn_ti							dph	2009-12-09T05:39:52Z						biological_process											owl:Class	
GO:0003373	biolink:NamedThing	dynamin family protein polymerization involved in membrane fission	The process of creating dynamin family protein polymers, compounds composed of a large number of dynamin family protein monomers. Dynamin family protein polymers form around lipid tubes and contribute to membrane fission.	got7fsn_ti							dph	2009-12-09T04:55:16Z						biological_process											owl:Class	
GO:0036081	biolink:NamedThing	extracellular ammonia-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	ionotropic ammonia receptor activity						bf	2011-12-20T04:47:48Z						molecular_function											owl:Class	
GO:0030437	biolink:NamedThing	ascospore formation	The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).	got7fsn_ti	ascospore biosynthesis|spore formation|sporulation				Note that ascospores and asci are separate biological structures. The ascus is the structure that contain the ascospores, but the development of the ascus is a different process than the formation of the ascospores themselves; for instance, some mutations affect sporulation without affecting ascus development. For this reason, GO:0030437 ascospore formation and GO:0075317 ascus development are different terms and are not linked.						GO:0007151			biological_process											owl:Class	
GO:0031829	biolink:NamedThing	type 4 serotonin receptor binding	Binding to a type 4 serotonin receptor.	got7fsn_ti	type 4 serotonin receptor ligand|5-hydroxytryptamine 4 receptor binding													molecular_function											owl:Class	
GO:0102124	biolink:NamedThing	gibberellin A12 16alpha,17 epoxidase activity	Catalysis of the reaction: gibberellin A12 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A12 + H2O + NAD(P).	got7fsn_ti												MetaCyc:RXN-11387		molecular_function											owl:Class	
GO:0021827	biolink:NamedThing	postnatal olfactory bulb interneuron migration	The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth.	got7fsn_ti														biological_process											owl:Class	
GO:0021823	biolink:NamedThing	cerebral cortex tangential migration using cell-cell interactions	The process in which neurons interact with each other to promote migration along a tangential plane.	got7fsn_ti	chain migration													biological_process											owl:Class	
GO:0032077	biolink:NamedThing	positive regulation of deoxyribonuclease activity	Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.	got7fsn_ti	up regulation of deoxyribonuclease activity|DNase activator|deoxyribonuclease activator|stimulation of deoxyribonuclease activity|upregulation of deoxyribonuclease activity|up-regulation of deoxyribonuclease activity|activation of deoxyribonuclease activity													biological_process											owl:Class	
GO:0051054	biolink:NamedThing	positive regulation of DNA metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.	got7fsn_ti	activation of DNA metabolic process|positive regulation of DNA metabolism|stimulation of DNA metabolic process|up-regulation of DNA metabolic process|up regulation of DNA metabolic process|upregulation of DNA metabolic process													biological_process											owl:Class	
GO:0140352	biolink:NamedThing	export from cell	The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.	got7fsn_ti	efflux						pg	2019-05-22T11:20:45Z						biological_process											owl:Class	
GO:0090663	biolink:NamedThing	galanin-activated signaling pathway	The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor.	got7fsn_ti	galanin signaling pathway|galanin-activated signalling pathway|galanin signalling pathway						tb	2015-10-21T13:38:04Z						biological_process											owl:Class	
GO:0007218	biolink:NamedThing	neuropeptide signaling pathway	The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.	got7fsn_ti	neuropeptide signalling pathway													biological_process											owl:Class	
GO:0042903	biolink:NamedThing	tubulin deacetylase activity	Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate.	got7fsn_ti												Reactome:R-HSA-5618331		molecular_function											owl:Class	
GO:0043982	biolink:NamedThing	histone H4-K8 acetylation	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.	got7fsn_ti	histone H4 acetylation at K8													biological_process											owl:Class	
GO:0043967	biolink:NamedThing	histone H4 acetylation	The modification of histone H4 by the addition of an acetyl group.	got7fsn_ti														biological_process											owl:Class	
GO:0042150	biolink:NamedThing	plasmid recombination	A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0060945	biolink:NamedThing	cardiac neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.	got7fsn_ti	heart neuron differentiation						dph	2009-09-29T02:45:33Z						biological_process											owl:Class	
GO:0000963	biolink:NamedThing	mitochondrial RNA processing	The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.	got7fsn_ti														biological_process											owl:Class	
GO:0140053	biolink:NamedThing	mitochondrial gene expression	The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	got7fsn_ti							pg	2017-06-26T10:57:45Z						biological_process											owl:Class	
GO:0098061	biolink:NamedThing	viral capsid, internal space	The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins.	got7fsn_ti	internal head protein						bm	2012-08-01T12:12:47Z						cellular_component											owl:Class	
GO:0030466	biolink:NamedThing	silent mating-type cassette heterochromatin assembly	Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.	got7fsn_ti	aging-dependent sterility|chromatin silencing at HML and HMR|chromatin silencing at silent mating-type cassette|silent mating-type cassette chromatin silencing|establishment of chromatin silencing at silent mating-type cassette|heterochromatic silencing at silent mating-type cassette	https://github.com/geneontology/go-ontology/issues/19112									GO:0035389|GO:0006347			biological_process											owl:Class	
GO:0035759	biolink:NamedThing	mesangial cell-matrix adhesion	The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.	got7fsn_ti							bf	2011-03-25T02:06:21Z						biological_process											owl:Class	
GO:0007160	biolink:NamedThing	cell-matrix adhesion	The binding of a cell to the extracellular matrix via adhesion molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0002307	biolink:NamedThing	CD8-positive, alpha-beta regulatory T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.	got7fsn_ti	CD8-positive, alpha-beta regulatory T-cell differentiation|CD8-positive, alpha-beta regulatory T lymphocyte differentiation|CD8-positive, alpha-beta regulatory T cell development|CD8-positive, alpha-beta regulatory T-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0103091	biolink:NamedThing	2-(7'-methylthio)heptylmalate synthase activity	Catalysis of the reaction: 2-oxo-9-methylthiononanoate + acetyl-CoA + H2O <=> H+ + 2-(7'-methylthio)heptylmalate + coenzyme A.	got7fsn_ti												MetaCyc:RXNQT-4175		molecular_function											owl:Class	
GO:0043912	biolink:NamedThing	D-lysine oxidase activity	Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide.	got7fsn_ti												EC:1.4.3.-		molecular_function											owl:Class	
GO:0050454	biolink:NamedThing	coenzyme F420 hydrogenase activity	Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420.	got7fsn_ti	F420-reducing hydrogenase activity|coenzyme F420-dependent hydrogenase activity|hydrogen:coenzyme F420 oxidoreductase activity|8-hydroxy-5-deazaflavin-reducing hydrogenase activity											KEGG_REACTION:R03025|EC:1.12.98.1|MetaCyc:COENZYME-F420-HYDROGENASE-RXN|RHEA:23760		molecular_function											owl:Class	
GO:0046995	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, with other known acceptors	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound.	got7fsn_ti												EC:1.12.98.-		molecular_function											owl:Class	
GO:0061802	biolink:NamedThing	anterior cell cortex	The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis.	got7fsn_ti							dph	2016-11-06T22:54:21Z						cellular_component											owl:Class	
GO:0070557	biolink:NamedThing	PCNA-p21 complex	A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication.	got7fsn_ti														cellular_component											owl:Class	
GO:0015276	biolink:NamedThing	ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	ionotropic receptor activity											Reactome:R-HSA-629595|Reactome:R-HSA-622326|Reactome:R-HSA-451310|Reactome:R-HSA-622325|Reactome:R-HSA-451311		molecular_function											owl:Class	
GO:0033566	biolink:NamedThing	gamma-tubulin complex localization	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of gamma-tubulin complex localization|gamma-tubulin complex localisation													biological_process											owl:Class	
GO:0051629	biolink:NamedThing	inhibition of epinephrine uptake	Any process that prevents the activation of the directed movement of epinephrine into a cell.	got7fsn_ti	inhibition of adrenaline uptake|inhibition of epinephrine import													biological_process											owl:Class	
GO:0043686	biolink:NamedThing	co-translational protein modification	The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome.	got7fsn_ti	co-translational modification|cotranslational protein modification|cotranslational modification|cotranslational amino acid modification|co-translational amino acid modification				This term should only be used to annotate a protein modification process that occurs after the start of translation but while the protein is still on the ribosome.									biological_process											owl:Class	
GO:0006069	biolink:NamedThing	ethanol oxidation	An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.	got7fsn_ti														biological_process											owl:Class	
GO:0006067	biolink:NamedThing	ethanol metabolic process	The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.	got7fsn_ti	ethanol metabolism													biological_process											owl:Class	
GO:0035777	biolink:NamedThing	pronephric distal tubule development	The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.	got7fsn_ti							bf	2011-04-04T11:06:01Z						biological_process											owl:Class	
GO:0039020	biolink:NamedThing	pronephric nephron tubule development	The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.	got7fsn_ti							bf	2010-07-02T10:11:36Z						biological_process											owl:Class	
GO:0071161	biolink:NamedThing	cyanophycin synthetase activity (L-arginine-adding)	Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1.	got7fsn_ti							mah	2009-11-17T05:19:54Z				EC:6.3.2.30|RHEA:23888		molecular_function											owl:Class	
GO:0060874	biolink:NamedThing	posterior semicircular canal development	The progession of the posterior semicircular canal from its initial formation to the mature structure.	got7fsn_ti							dph	2009-08-13T09:42:39Z						biological_process											owl:Class	
GO:0002111	biolink:NamedThing	BRCA2-BRAF35 complex	A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis.	got7fsn_ti														cellular_component											owl:Class	
GO:0036385	biolink:NamedThing	nucleoid DNA packaging	Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid.	got7fsn_ti							bf	2013-05-30T10:36:05Z						biological_process											owl:Class	
GO:0006323	biolink:NamedThing	DNA packaging	Any process in which DNA and associated proteins are formed into a compact, orderly structure.	got7fsn_ti	DNA organisation|DNA condensation|DNA organization													biological_process											owl:Class	
GO:0005606	biolink:NamedThing	laminin-1 complex	A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.	got7fsn_ti	laminin-111 complex													cellular_component											owl:Class	
GO:0035725	biolink:NamedThing	sodium ion transmembrane transport	A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	sodium ion membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2011-03-10T02:52:36Z						biological_process											owl:Class	
GO:0006814	biolink:NamedThing	sodium ion transport	The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	mitochondrial sodium/calcium ion exchange|sodium channel auxiliary protein activity|sodium/potassium transport|sodium:solute transport|sodium:calcium exchange|sodium transport										GO:0006834|GO:0016974			biological_process											owl:Class	
GO:2000039	biolink:NamedThing	regulation of trichome morphogenesis	Any process that modulates the frequency, rate or extent of trichome morphogenesis.	got7fsn_ti	regulation of trichome cell morphogenesis during differentiation						tb	2010-08-05T11:36:31Z						biological_process											owl:Class	
GO:2000024	biolink:NamedThing	regulation of leaf development	Any process that modulates the frequency, rate or extent of leaf development.	got7fsn_ti							tb	2010-08-05T11:25:14Z						biological_process											owl:Class	
GO:0090737	biolink:NamedThing	telomere maintenance via telomere trimming	A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication.	got7fsn_ti							tb	2017-02-07T16:51:24Z						biological_process											owl:Class	
GO:0005885	biolink:NamedThing	Arp2/3 protein complex	A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.	got7fsn_ti														cellular_component											owl:Class	
GO:0032010	biolink:NamedThing	phagolysosome	A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes.	got7fsn_ti	late phagosome|late phagocytic vesicle											Wikipedia:Phagolysosome		cellular_component											owl:Class	
GO:0036074	biolink:NamedThing	metaplastic ossification	Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division.	got7fsn_ti	metaplasia				Some intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.		bf	2011-12-19T01:50:35Z						biological_process											owl:Class	
GO:0036072	biolink:NamedThing	direct ossification	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.	got7fsn_ti							bf	2011-12-19T01:47:22Z						biological_process											owl:Class	
GO:0102388	biolink:NamedThing	UDP-N,N'-diacetylbacillosamine 2-epimerase activity	Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+.	got7fsn_ti												RHEA:34491|MetaCyc:RXN-13574|EC:3.2.1.184		molecular_function											owl:Class	
GO:0030957	biolink:NamedThing	Tat protein binding	Binding to Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus.	got7fsn_ti														molecular_function											owl:Class	
GO:0060884	biolink:NamedThing	clearance of cells from fusion plate	The morphogenetic process in which cells are removed from the inner loop of a semicircular canal.	got7fsn_ti							dph	2009-08-13T12:25:59Z						biological_process											owl:Class	
GO:0140025	biolink:NamedThing	contractile vacuole tethering involved in discharge	The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.	got7fsn_ti	contractile vacuole tethering to plasma membrane						pg	2017-05-02T09:50:10Z						biological_process											owl:Class	
GO:0106325	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP.	got7fsn_ti							hjd	2020-09-30T13:37:55Z				EC:2.4.1.148|RHEA:56188		molecular_function											owl:Class	
GO:0047225	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP.	got7fsn_ti	uridine diphosphoacetylglucosamine-mucin beta(1->6)-acetylglucosaminyltransferase B|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity|core 4 beta6-GalNAc-transferase activity|core 6beta-GalNAc-transferase B|UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity|core 6-beta-GalNAc-transferase B activity											MetaCyc:2.4.1.148-RXN|RHEA:16552|EC:2.4.1.148		molecular_function											owl:Class	
GO:0034565	biolink:NamedThing	1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity	Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol.	got7fsn_ti												EC:3.5.99.-|UM-BBD_reactionID:r0872		molecular_function											owl:Class	
GO:0003314	biolink:NamedThing	heart rudiment morphogenesis	The process in which the anatomical structures of the heart rudiment are generated and organized.	got7fsn_ti	heart cone morphogenesis						dph	2009-10-27T08:38:04Z						biological_process											owl:Class	
GO:0035585	biolink:NamedThing	calcium-mediated signaling using extracellular calcium source	A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.	got7fsn_ti	extracellular calcium influx|calcium signaling using extracellular calcium source|calcium-mediated signalling using extracellular calcium source|calcium signalling using extracellular calcium source						bf	2010-10-18T11:04:27Z						biological_process											owl:Class	
GO:0051841	biolink:NamedThing	positive regulation by host of cytolysis of symbiont cells	Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	stimulation by host of cytolysis of symbiont cells|up-regulation by host of cytolysis of symbiont cells|upregulation by host of cytolysis of symbiont cells|activation by host of cytolysis of symbiont cells|up regulation by host of cytolysis of symbiont cells													biological_process											owl:Class	
GO:0051839	biolink:NamedThing	regulation by host of cytolysis of symbiont cells	Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0034464	biolink:NamedThing	BBSome	A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B.	got7fsn_ti	Bardet-Biedl syndrome complex													cellular_component											owl:Class	
GO:0050727	biolink:NamedThing	regulation of inflammatory response	Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.	got7fsn_ti														biological_process											owl:Class	
GO:0140064	biolink:NamedThing	peptide crotonyltransferase activity	Catalysis of the reaction: crotonyl-CoA + lysine in peptide = CoA + N-crotonyl-lysine-peptide.	got7fsn_ti	protein crotonyltransferase activity						pg	2017-07-20T16:40:57Z						molecular_function											owl:Class	
GO:0072055	biolink:NamedThing	renal cortex development	The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.	got7fsn_ti							mah	2010-01-25T04:01:12Z						biological_process											owl:Class	
GO:0097664	biolink:NamedThing	SCF-Grr1/Pof2 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe).	got7fsn_ti							pr	2014-10-06T10:27:10Z						cellular_component											owl:Class	
GO:1990226	biolink:NamedThing	histone methyltransferase binding	Binding to a histone methyltransferase enzyme.	got7fsn_ti							pr	2013-11-07T11:59:58Z						molecular_function											owl:Class	
GO:0033885	biolink:NamedThing	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity	Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate.	got7fsn_ti	(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity|lipid-phosphate phosphatase activity|hydroxy lipid phosphatase activity|hydroxy fatty acid phosphatase activity|soluble epoxide hydrolase activity|sEH|(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase activity|dihydroxy fatty acid phosphatase activity											KEGG_REACTION:R07582|EC:3.1.3.76|RHEA:16537|MetaCyc:3.1.3.76-RXN		molecular_function											owl:Class	
GO:0047057	biolink:NamedThing	vitamin-K-epoxide reductase (warfarin-sensitive) activity	Catalysis of the reaction: phylloquinol + a protein with a disulfide bond = phylloquinone + a protein with reduced L-cysteine residues.	got7fsn_ti	vitamin K1 epoxide reductase activity|phylloquinone epoxide reductase activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.1.4.1.							Reactome:R-HSA-6806647|RHEA:57744|Reactome:R-HSA-159790|EC:1.17.4.4|MetaCyc:1.1.4.1-RXN		molecular_function											owl:Class	
GO:0016900	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule.	got7fsn_ti	oxidoreductase activity, acting on the CH-OH group of donors, disulphide as acceptor											EC:1.1.4.-		molecular_function											owl:Class	
GO:0004638	biolink:NamedThing	phosphoribosylaminoimidazole carboxylase activity	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2).	got7fsn_ti	ADE2|1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity|5-phosphoribosyl-5-aminoimidazole carboxylase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity|AIR carboxylase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]|class II PurE|5-amino-1-ribosylimidazole 5-phosphate carboxylase activity											KEGG_REACTION:R04209|EC:4.1.1.21|MetaCyc:AIRCARBOXY-RXN|Reactome:R-HSA-73806|RHEA:10792		molecular_function											owl:Class	
GO:0035122	biolink:NamedThing	embryonic medial fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.	got7fsn_ti	embryonic unpaired fin morphogenesis													biological_process											owl:Class	
GO:0070693	biolink:NamedThing	P-TEFb-cap methyltransferase complex	A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase.	got7fsn_ti	P-TEFb-Pcm1 complex|Cdk9-Pcm1 complex						mah	2009-06-04T02:38:58Z						cellular_component											owl:Class	
GO:0002451	biolink:NamedThing	peripheral B cell tolerance induction	Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.	got7fsn_ti	peripheral B lymphocyte tolerance induction|peripheral B-lymphocyte tolerance induction|peripheral B-cell tolerance induction													biological_process											owl:Class	
GO:0000323	biolink:NamedThing	lytic vacuole	A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.	got7fsn_ti														cellular_component											owl:Class	
GO:0045200	biolink:NamedThing	establishment of neuroblast polarity	The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.	got7fsn_ti	establishment of neuroblast cell polarity										GO:0043340|GO:0043343			biological_process											owl:Class	
GO:0030010	biolink:NamedThing	establishment of cell polarity	The specification and formation of anisotropic intracellular organization or cell growth patterns.	got7fsn_ti	bud site selection/establishment of cell polarity|cell polarization										GO:0030468|GO:0000283			biological_process											owl:Class	
GO:0019379	biolink:NamedThing	sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)	The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).	got7fsn_ti	sulphate assimilation, phosphoadenylyl sulphate reduction by a phosphoadenylyl-sulphate reductase (thioredoxin)											MetaCyc:SO4ASSIM-PWY		biological_process											owl:Class	
GO:0000103	biolink:NamedThing	sulfate assimilation	The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.	got7fsn_ti	sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|sulphate assimilation|sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor										GO:0019378			biological_process											owl:Class	
GO:0044325	biolink:NamedThing	transmembrane transporter binding	Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.	got7fsn_ti	ion channel binding	https://github.com/geneontology/go-ontology/issues/21331					jl	2010-08-04T12:52:59Z						molecular_function											owl:Class	
GO:0042267	biolink:NamedThing	natural killer cell mediated cytotoxicity	The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.	got7fsn_ti	NK cell mediated cell death|natural killer-cell mediated cytolysis|NK cell mediated cell killing|natural killer cell mediated cytolysis|natural killer cell mediated cell death|natural killer cell mediated cell killing|killer activity|NK cell mediated cytotoxicity|NK cell mediated cytolysis				Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.									biological_process											owl:Class	
GO:0001909	biolink:NamedThing	leukocyte mediated cytotoxicity	The directed killing of a target cell by a leukocyte.	got7fsn_ti	immune cell mediated cell death|leucocyte mediated cytotoxicity|immune cell mediated cytotoxicity|immune cell mediated cell killing				Note that this term and its children describe contact-dependent killing of target cells by lymphocytes and myeloid cells of the immune system.									biological_process											owl:Class	
GO:0061286	biolink:NamedThing	mesonephric capsule morphogenesis	The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	got7fsn_ti							dph	2010-09-02T01:53:31Z						biological_process											owl:Class	
GO:0072128	biolink:NamedThing	renal capsule morphogenesis	The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.	got7fsn_ti							mah	2010-02-22T02:06:19Z						biological_process											owl:Class	
GO:0051255	biolink:NamedThing	spindle midzone assembly	The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.	got7fsn_ti	spindle midzone biogenesis|spindle midzone formation|spindle midzone biosynthesis													biological_process											owl:Class	
GO:0007593	biolink:NamedThing	chitin-based cuticle sclerotization	The process of hardening of a chitin-based cuticle.	got7fsn_ti	cuticle hardening|chitin-based cuticle tanning										GO:0045452			biological_process											owl:Class	
GO:0007591	biolink:NamedThing	molting cycle, chitin-based cuticle	The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster.	got7fsn_ti	chitin-based cuticle molting cycle													biological_process											owl:Class	
GO:0020031	biolink:NamedThing	polar ring of apical complex	An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite.	got7fsn_ti	anterior polar ring of apical complex|upper polar ring of apical complex													cellular_component											owl:Class	
GO:0050358	biolink:NamedThing	tropinone reductase activity	Catalysis of the reaction: NADP(+) + pseudotropine = H(+) + NADPH + tropinone.	got7fsn_ti	tropinone (psi-tropine-forming) reductase activity|pseudotropine forming tropinone reductase activity|pseudotropine:NADP+ 3-oxidoreductase activity|tropinone reductase II activity											KEGG_REACTION:R06734|EC:1.1.1.236|RHEA:24244|MetaCyc:TROPINONE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0042983	biolink:NamedThing	amyloid precursor protein biosynthetic process	The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.	got7fsn_ti	amyloid precursor protein formation|amyloid precursor protein anabolism|amyloid precursor protein synthesis|amyloid precursor protein biosynthesis|APP biosynthesis|APP biosynthetic process													biological_process											owl:Class	
GO:0042982	biolink:NamedThing	amyloid precursor protein metabolic process	The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.	got7fsn_ti	APP metabolic process|amyloid precursor protein metabolism|APP metabolism													biological_process											owl:Class	
GO:0019610	biolink:NamedThing	3-hydroxyphenylacetate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.	got7fsn_ti	3-hydroxyphenylacetate catabolism|3-hydroxyphenylacetate degradation|3-hydroxyphenylacetate breakdown											MetaCyc:3-HYDROXYPHENYLACETATE-DEGRADATION-PWY		biological_process											owl:Class	
GO:0062014	biolink:NamedThing	negative regulation of small molecule metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.	got7fsn_ti	negative regulation of small molecule metabolism						dph	2018-03-19T14:27:23Z						biological_process											owl:Class	
GO:0009346	biolink:NamedThing	ATP-independent citrate lyase complex	Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity. This enzyme has only been found in bacteria.	got7fsn_ti	citrate synthase complex|citrate lyase complex	https://github.com/geneontology/go-ontology/issues/21028			Note that this complex has only been found in bacteria. For eukaryotic cytrate lyases, consider GO:0140615 ; ATP-dependent citrate lyase complex.							MetaCyc:ACECITLY-CPLX		cellular_component											owl:Class	
GO:0098926	biolink:NamedThing	postsynaptic signal transduction	Signal transduction in which the initial step occurs in a postsynapse.	got7fsn_ti	postsynaptic signaling pathway				Do not directly annotate. This term is intended for automatically grouping annotations to signal transduction classes extended with has_start_location/occurs_in postsynapse or one of its parts.									biological_process											owl:Class	
GO:0097401	biolink:NamedThing	synaptic vesicle lumen acidification	The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.	got7fsn_ti	synaptic vesicle proton loading|synaptic vesicle lumen pH reduction						pr	2012-10-25T09:03:34Z						biological_process											owl:Class	
GO:0038036	biolink:NamedThing	sphingosine-1-phosphate receptor activity	Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein.	got7fsn_ti	S1P receptor activity						bf	2011-10-28T03:46:54Z						molecular_function											owl:Class	
GO:0031047	biolink:NamedThing	gene silencing by RNA	Any process in which RNA molecules inactivate expression of target genes.	got7fsn_ti	RNA-mediated gene silencing													biological_process											owl:Class	
GO:0016458	biolink:NamedThing	gene silencing	Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.	got7fsn_ti					This is a rather broad grouping term.  While it was originally defined for long-term, heritable, epigenetic effects, short term effects on expression mediated by RNA are also frequently referred to as gene silencing, and are grouped under this class.							Wikipedia:Gene_silencing		biological_process											owl:Class	
GO:0008444	biolink:NamedThing	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H(+).	got7fsn_ti	phosphatidylglycerolphosphate synthase activity|CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase activity|CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase activity|3-phosphatidyl-1'-glycerol-3'-phosphate synthase activity|CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase activity|phosphatidylglycerol phosphate synthase activity|glycerophosphate phosphatidyltransferase activity|CDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity|PGP synthase activity|glycerol phosphate phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase activity|glycerol 3-phosphate phosphatidyltransferase activity|CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase activity|sn-glycerol-3-phosphate phosphatidyltransferase activity|phosphatidylglycerophosphate synthetase activity|phosphatidylglycerol phosphate synthetase activity|phosphatidylglycerophosphate synthase activity											Reactome:R-HSA-1482939|EC:2.7.8.5|KEGG_REACTION:R01801|MetaCyc:PHOSPHAGLYPSYN-RXN|RHEA:12593		molecular_function											owl:Class	
GO:0017169	biolink:NamedThing	CDP-alcohol phosphatidyltransferase activity	Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol.	got7fsn_ti														molecular_function											owl:Class	
GO:0021878	biolink:NamedThing	forebrain astrocyte fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0060018	biolink:NamedThing	astrocyte fate commitment	The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.	got7fsn_ti														biological_process											owl:Class	
GO:0050270	biolink:NamedThing	S-adenosylhomocysteine deaminase activity	Catalysis of the reaction: S-adenosyl-L-homocysteine + H(2)O + H(+) = S-inosyl-L-homocysteine + NH(4)(+).	got7fsn_ti	adenosylhomocysteine deaminase activity|S-adenosyl-L-homocysteine aminohydrolase activity											RHEA:20716|EC:3.5.4.28|MetaCyc:S-ADENOSYLHOMOCYSTEINE-DEAMINASE-RXN|KEGG_REACTION:R00193		molecular_function											owl:Class	
GO:0102665	biolink:NamedThing	indole-3-acetyl-glutamate synthetase activity	Catalysis of the reaction: indole-3-acetate + L-glutamate + ATP <=> H+ + indole-3-acetyl-glutamate + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-2947		molecular_function											owl:Class	
GO:0050965	biolink:NamedThing	detection of temperature stimulus involved in sensory perception of pain	The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.	got7fsn_ti	sensory perception of pain, sensory detection of thermal stimulus|sensory transduction of temperature stimulus during perception of pain|perception of pain, detection of temperature stimulus|sensory detection of thermal stimulus during sensory perception of pain|sensory transduction of thermal stimulus during sensory perception of pain|sensory detection of temperature stimulus during perception of pain|thermal nociception|perception of pain, sensory transduction of temperature stimulus|perception of pain, sensory detection of temperature stimulus|sensory perception of pain, sensory transduction of thermal stimulus													biological_process											owl:Class	
GO:0043084	biolink:NamedThing	penile erection	The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.	got7fsn_ti												Wikipedia:Erection#Penile_erection		biological_process											owl:Class	
GO:0003052	biolink:NamedThing	circadian regulation of systemic arterial blood pressure	Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.	got7fsn_ti														biological_process											owl:Class	
GO:0032422	biolink:NamedThing	purine-rich negative regulatory element binding	Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.	got7fsn_ti	PNR element binding													molecular_function											owl:Class	
GO:0070264	biolink:NamedThing	transcription factor TFIIIE complex	A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0102612	biolink:NamedThing	syn-pimaradiene 6beta-hydroxylase activity	Catalysis of the reaction: 9beta-pimara-7,15-diene + NADPH + O2 + H+ <=> 6beta-hydroxy-syn-pimaradiene + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15452		molecular_function											owl:Class	
GO:0016905	biolink:NamedThing	myosin heavy chain kinase activity	Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate.	got7fsn_ti	myosin heavy-chain kinase activity|ATP:myosin heavy-chain O-phosphotransferase activity|myosin-heavy-chain kinase activity|STK6|myosin II heavy chain kinase activity|myosin I heavy chain kinase activity|myosin I heavy-chain kinase activity|MHCK|myosin heavy chain kinase A activity|calmodulin-dependent myosin heavy chain kinase activity|myosin II heavy-chain kinase activity|MIHC kinase activity|ATP:myosin-heavy-chain O-phosphotransferase activity											RHEA:11424|EC:2.7.11.7		molecular_function											owl:Class	
GO:0018940	biolink:NamedThing	orcinol metabolic process	The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants.	got7fsn_ti	orcin metabolic process|orcinol metabolism|orcin metabolism											MetaCyc:P342-PWY|UM-BBD_pathwayID:orc		biological_process											owl:Class	
GO:0035628	biolink:NamedThing	cystic duct development	The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct.	got7fsn_ti							bf	2010-12-10T01:24:28Z						biological_process											owl:Class	
GO:0015592	biolink:NamedThing	methylgalactoside transmembrane transporter activity	Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.	got7fsn_ti	galactose/glucose (methylgalactoside) porter activity													molecular_function											owl:Class	
GO:0034002	biolink:NamedThing	(R)-limonene synthase activity	Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate.	got7fsn_ti	(+)-limonene synthase activity|geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming] activity|geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming] activity											EC:4.2.3.20|KEGG_REACTION:R06120|MetaCyc:4.2.3.20-RXN|RHEA:10940		molecular_function											owl:Class	
GO:0009442	biolink:NamedThing	allantoin assimilation pathway	The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP.	got7fsn_ti	allantoin catabolism via ureidoglycolate|allantoin degradation pathway|allantoin catabolic process via ureidoglycolate											MetaCyc:PWY0-41		biological_process											owl:Class	
GO:0000256	biolink:NamedThing	allantoin catabolic process	The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.	got7fsn_ti	allantoin degradation|allantoin breakdown|allantoin catabolism													biological_process											owl:Class	
GO:0018544	biolink:NamedThing	4-carboxy-4'-sulfoazobenzene reductase activity	Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate.	got7fsn_ti	4-carboxy-4'-sulphoazobenzene reductase activity											UM-BBD_reactionID:r0543		molecular_function											owl:Class	
GO:0048795	biolink:NamedThing	swim bladder morphogenesis	The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	got7fsn_ti	gas bladder morphogenesis													biological_process											owl:Class	
GO:0099536	biolink:NamedThing	synaptic signaling	Cell-cell signaling to, from or within a synapse.	got7fsn_ti														biological_process											owl:Class	
GO:0008730	biolink:NamedThing	L(+)-tartrate dehydratase activity	Catalysis of the reaction: L-tartrate = H(2)O + oxaloacetate.	got7fsn_ti	L-tartrate dehydratase activity|tartrate dehydratase activity|(R,R)-tartrate hydro-lyase activity|L-(+)-tartaric acid dehydratase activity|tartaric acid dehydrase activity|(R,R)-tartrate hydro-lyase (oxaloacetate-forming)											MetaCyc:LTARTDEHYDRA-RXN|EC:4.2.1.32|RHEA:15413|KEGG_REACTION:R00339		molecular_function											owl:Class	
GO:0086003	biolink:NamedThing	cardiac muscle cell contraction	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell.	got7fsn_ti							tb	2011-11-10T07:48:15Z						biological_process											owl:Class	
GO:0050115	biolink:NamedThing	myosin-light-chain-phosphatase activity	Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate.	got7fsn_ti	myosin-light-chain-phosphate phosphohydrolase activity|[Myosin light-chain]-phosphatase activity|protein phosphatase 2A|myosin light-chain kinase phosphatase activity|myosin light chain kinase phosphatase activity|myosin-light-chain phosphatase activity											EC:3.1.3.53|Reactome:R-HSA-419232|MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0015558	biolink:NamedThing	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity	Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid.	got7fsn_ti	p-aminobenzoyl-glutamate uptake transmembrane transporter activity|p-aminobenzoyl-glutamate uptake permease activity|p-aminobenzoyl-glutamate transporter activity|p-aminobenzoyl-glutamate transmembrane transporter activity										GO:0015569			molecular_function											owl:Class	
GO:0070842	biolink:NamedThing	aggresome assembly	The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.	got7fsn_ti							mah	2009-07-31T01:30:25Z						biological_process											owl:Class	
GO:0070841	biolink:NamedThing	inclusion body assembly	The aggregation, arrangement and bonding together of a set of components to form an inclusion body.	got7fsn_ti							mah	2009-07-31T01:28:14Z						biological_process											owl:Class	
GO:0008237	biolink:NamedThing	metallopeptidase activity	Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	got7fsn_ti	metalloprotease activity|metalloproteinase activity											Reactome:R-HSA-5211405|Reactome:R-HSA-5211356|Reactome:R-HSA-5211391|Reactome:R-HSA-2220976|Reactome:R-HSA-2666278|Reactome:R-HSA-2022399|Reactome:R-HSA-157632|Reactome:R-HSA-2022396|Reactome:R-HSA-2022368|Reactome:R-HSA-5211340|Reactome:R-HSA-9013284|Reactome:R-HSA-2022393|Reactome:R-HSA-8986181|Reactome:R-HSA-9604264|Reactome:R-HSA-9662837|Reactome:R-HSA-193679|Reactome:R-HSA-2730752|Reactome:R-HSA-157629|Reactome:R-HSA-2220944|Reactome:R-HSA-3928660|Reactome:R-HSA-5211387|Reactome:R-HSA-5211400		molecular_function											owl:Class	
GO:0098800	biolink:NamedThing	inner mitochondrial membrane protein complex	Any protein complex that is part of the inner mitochondrial membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0043720	biolink:NamedThing	3-keto-5-aminohexanoate cleavage activity	Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate.	got7fsn_ti	3-keto-5-aminohexanoate cleavage enzyme											RHEA:31555|MetaCyc:R125-RXN		molecular_function											owl:Class	
GO:0098788	biolink:NamedThing	dendritic knob	The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium.	got7fsn_ti	apical dendritic knob													cellular_component											owl:Class	
GO:0051230	biolink:NamedThing	spindle disassembly	The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.	got7fsn_ti	spindle catabolism|spindle breakdown|spindle degradation													biological_process											owl:Class	
GO:0018261	biolink:NamedThing	peptidyl-lysine guanylylation	The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine.	got7fsn_ti												RESID:AA0228		biological_process											owl:Class	
GO:0018260	biolink:NamedThing	protein guanylylation	The addition of phospho-guanosine to a protein amino acid.	got7fsn_ti	protein amino acid guanylylation													biological_process											owl:Class	
GO:0009729	biolink:NamedThing	detection of brassinosteroid stimulus	The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of brassinosteroid stimulus													biological_process											owl:Class	
GO:0009741	biolink:NamedThing	response to brassinosteroid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.	got7fsn_ti	response to brassinosteroid stimulus													biological_process											owl:Class	
GO:0106239	biolink:NamedThing	9,13-epoxylabda-14-ene synthase activity	Catalysis of the reaction:peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate.	got7fsn_ti							hjd	2019-12-19T16:00:49Z				EC:4.2.3.189|RHEA:54512		molecular_function											owl:Class	
GO:0010558	biolink:NamedThing	negative regulation of macromolecule biosynthetic process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti														biological_process											owl:Class	
GO:0035891	biolink:NamedThing	exit from host cell	The directed movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	ejection from host cell|host cell exit						bf	2011-06-15T02:09:28Z						biological_process											owl:Class	
GO:0031249	biolink:NamedThing	denatured protein binding	Binding to a denatured protein.	got7fsn_ti					Note that this term should not be confused with 'unfolded protein binding ; GO:0051082', which usually refers to proteins that have not yet folded into their active states. Denatured proteins once were in their correct functional conformations, but have become incorrectly folded, and often form aggregates.									molecular_function											owl:Class	
GO:1990253	biolink:NamedThing	cellular response to leucine starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.	got7fsn_ti							al	2013-12-10T11:55:10Z						biological_process											owl:Class	
GO:0099121	biolink:NamedThing	fungal sorus development	The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure.	got7fsn_ti														biological_process											owl:Class	
GO:0004883	biolink:NamedThing	glucocorticoid receptor activity	Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.	got7fsn_ti														molecular_function											owl:Class	
GO:0003707	biolink:NamedThing	steroid hormone receptor activity	Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.	got7fsn_ti					Some steroid hormone receptors reside in the plasma membrane and signal through second messengers or other intracellular signal transduction pathways. For steroid hormone receptors that act in the nucleus to regulate transcription, consider also annotating to the terms: nuclear receptor activity ; GO:0004879' or nuclear receptor transcription coactivator activity ; GO:0030374'.									molecular_function											owl:Class	
GO:0010617	biolink:NamedThing	circadian regulation of calcium ion oscillation	Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours.	got7fsn_ti	circadian regulation of cytosolic calcium ion homeostasis|circadian regulation of [Ca2+]cyt oscillation|circadian regulation of Ca2+ oscillation|circadian regulation of cytosolic free calcium ion oscillation													biological_process											owl:Class	
GO:0071005	biolink:NamedThing	U2-type precatalytic spliceosome	A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.	got7fsn_ti	mammalian U2-type spliceosomal complex B1|mammalian U2-type spliceosomal complex B|yeast U12-type spliceosomal complex A2-1|GT-AG precatalytic spliceosome|major precatalytic spliceosome						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0061742	biolink:NamedThing	chaperone-mediated autophagy translocation complex	A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy.	got7fsn_ti	CMA translocation complex|CMA receptor complex|chaperone-mediated autophagy receptor complex	https://github.com/geneontology/go-ontology/issues/20850					dph	2015-10-23T07:39:04Z						cellular_component											owl:Class	
GO:0044858	biolink:NamedThing	plasma membrane raft polarization	The clustering and aggregation of a plasma membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.	got7fsn_ti	plasma membrane polarization						jl	2014-07-23T16:21:39Z						biological_process											owl:Class	
GO:0061471	biolink:NamedThing	karyomere assembly	The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle.	got7fsn_ti							dph	2012-11-02T09:13:59Z						biological_process											owl:Class	
GO:0010605	biolink:NamedThing	negative regulation of macromolecule metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti														biological_process											owl:Class	
GO:0018649	biolink:NamedThing	tetrahydrofuran hydroxylase activity	Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran.	got7fsn_ti												EC:1.14.13.-|UM-BBD_reactionID:r0017		molecular_function											owl:Class	
GO:1900603	biolink:NamedThing	tensidol A metabolic process	The chemical reactions and pathways involving tensidol A.	got7fsn_ti	tensidol A metabolism						di	2012-05-15T06:57:47Z						biological_process											owl:Class	
GO:0005483	biolink:NamedThing	soluble NSF attachment protein activity	Binding to both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.	got7fsn_ti	SNAP	https://github.com/geneontology/go-ontology/issues/16807												molecular_function											owl:Class	
GO:0010324	biolink:NamedThing	membrane invagination	The infolding of a membrane.	got7fsn_ti	single-organism membrane invagination						jl	2013-12-02T13:58:34Z			GO:1902534			biological_process											owl:Class	
GO:0044242	biolink:NamedThing	cellular lipid catabolic process	The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.	got7fsn_ti	cellular lipid catabolism|cellular lipid degradation|cellular lipid breakdown													biological_process											owl:Class	
GO:0047552	biolink:NamedThing	2-oxoaldehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+.	got7fsn_ti	2-oxoaldehyde:NADP+ 2-oxidoreductase activity|NADP-dependent alpha-ketoaldehyde dehydrogenase activity|2-ketoaldehyde dehydrogenase|alpha-ketoaldehyde dehydrogenase activity|methylglyoxal dehydrogenase activity|NADP-linked alpha-ketoaldehyde dehydrogenase activity											RHEA:18129|MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NADP+-RXN|EC:1.2.1.49		molecular_function											owl:Class	
GO:0033781	biolink:NamedThing	cholesterol 24-hydroxylase activity	Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+).	got7fsn_ti	cholesterol 24S-hydroxylase activity|cytochrome P450 46A1|CYP46A1|cholesterol 24-monooxygenase activity|cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity|CYP46											EC:1.14.14.25|Reactome:R-HSA-192061|KEGG_REACTION:R07207|RHEA:22716|MetaCyc:1.14.13.98-RXN		molecular_function											owl:Class	
GO:0038030	biolink:NamedThing	non-canonical Wnt signaling pathway via MAPK cascade	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the MAPKKK cascade.	got7fsn_ti	non-canonical Wnt-activated signaling pathway via MAPK cascade|non-canonical Wnt receptor signaling pathway via MAPK signaling|non-canonical Wnt receptor signaling pathway via MAPKKK cascade|non-canonical Wnt receptor signaling pathway via MAPK cascade|non-canonical Wnt receptor signalling pathway via MAPKKK cascade						bf	2011-09-08T01:46:07Z						biological_process											owl:Class	
GO:0061264	biolink:NamedThing	mesonephric glomerular mesangial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.	got7fsn_ti							dph	2010-08-30T02:59:11Z						biological_process											owl:Class	
GO:0018050	biolink:NamedThing	C-terminal peptidyl-threonine amidation	The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0097		biological_process											owl:Class	
GO:0035921	biolink:NamedThing	desmosome disassembly	The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.	got7fsn_ti	desmosome dissociation						bf	2011-07-05T01:33:25Z						biological_process											owl:Class	
GO:0022411	biolink:NamedThing	cellular component disassembly	A cellular process that results in the breakdown of a cellular component.	got7fsn_ti	cell structure disassembly|cellular component disassembly at cellular level										GO:0071845			biological_process											owl:Class	
GO:0061472	biolink:NamedThing	karyomere membrane fusion	Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus.	got7fsn_ti							dph	2012-11-02T09:25:41Z						biological_process											owl:Class	
GO:0106123	biolink:NamedThing	reservosome	A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes.	got7fsn_ti							hjd	2018-05-03T17:48:59Z						cellular_component											owl:Class	
GO:0021982	biolink:NamedThing	pineal gland development	The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.	got7fsn_ti	epiphysis development													biological_process											owl:Class	
GO:0018215	biolink:NamedThing	protein phosphopantetheinylation	The modification of a protein amino acid by phosphopantetheinylation.	got7fsn_ti	protein amino acid phosphopantetheinylation													biological_process											owl:Class	
GO:1903430	biolink:NamedThing	negative regulation of cell maturation	Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.	got7fsn_ti	negative regulation of functional differentiation|inhibition of cell maturation|downregulation of cell maturation|down-regulation of functional differentiation|downregulation of functional differentiation|inhibition of functional differentiation|down regulation of cell maturation|down regulation of functional differentiation|down-regulation of cell maturation						jl	2014-09-15T13:31:32Z						biological_process											owl:Class	
GO:0089720	biolink:NamedThing	caspase binding	Binding to a caspase family protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0002020	biolink:NamedThing	protease binding	Binding to a protease or a peptidase.	got7fsn_ti												Reactome:R-HSA-1297354		molecular_function											owl:Class	
GO:0008476	biolink:NamedThing	protein-tyrosine sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.	got7fsn_ti	protein-tyrosine sulphotransferase activity|tyrosylprotein sulfotransferase activity|3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity											Reactome:R-HSA-9668148|Reactome:R-HSA-9668023|MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN|EC:2.8.2.20|Reactome:R-HSA-8954262|RHEA:16801		molecular_function											owl:Class	
GO:2000383	biolink:NamedThing	regulation of ectoderm development	Any process that modulates the frequency, rate or extent of ectoderm development.	got7fsn_ti							vk	2011-02-15T03:17:10Z						biological_process											owl:Class	
GO:0072210	biolink:NamedThing	metanephric nephron development	The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.	got7fsn_ti							mah	2010-03-18T12:52:57Z						biological_process											owl:Class	
GO:0004392	biolink:NamedThing	heme oxygenase (decyclizing) activity	Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin  + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase].	got7fsn_ti	heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)|heme oxidase activity|haem oxygenase activity|heme oxygenase activity|haem oxidase activity|haem oxygenase (decyclizing) activity|ORP33 proteins	https://github.com/geneontology/go-ontology/issues/21106										MetaCyc:HEME-OXYGENASE-DECYCLIZING-RXN|EC:1.14.14.18|RHEA:21764|Reactome:R-HSA-189398		molecular_function											owl:Class	
GO:0018154	biolink:NamedThing	peptide cross-linking via (2R,6R)-lanthionine	The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine).	got7fsn_ti												RESID:AA0110		biological_process											owl:Class	
GO:0102431	biolink:NamedThing	acyl-lipid omega-(9-4) desaturase	Catalysis of the reaction: linoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H(+) <=> pinolenoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O.	got7fsn_ti	linoleate delta5 desaturase activity											MetaCyc:RXN-13858|EC:1.14.19.12|RHEA:46236		molecular_function											owl:Class	
GO:0046020	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter by pheromones	Any process involving pheromones that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of transcription from Pol II promoter by pheromones|down regulation of transcription from RNA polymerase II promoter by pheromones|downregulation of transcription from RNA polymerase II promoter by pheromones|inhibition of transcription from RNA polymerase II promoter by pheromones|down-regulation of transcription from RNA polymerase II promoter by pheromones													biological_process											owl:Class	
GO:0045996	biolink:NamedThing	negative regulation of transcription by pheromones	Any process involving pheromones that stops, prevents or reduces the rate of transcription.	got7fsn_ti	down regulation of transcription by pheromones|down-regulation of transcription by pheromones|downregulation of transcription by pheromones|inhibition of transcription by pheromones													biological_process											owl:Class	
GO:0006536	biolink:NamedThing	glutamate metabolic process	The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.	got7fsn_ti	glutamic acid metabolic process|glutamate metabolism|glutamic acid metabolism											Wikipedia:Glutamic_acid		biological_process											owl:Class	
GO:0070664	biolink:NamedThing	negative regulation of leukocyte proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.	got7fsn_ti	downregulation of leukocyte proliferation|inhibition of leukocyte proliferation|down regulation of leukocyte proliferation|down-regulation of leukocyte proliferation						mah	2009-05-28T05:34:50Z						biological_process											owl:Class	
GO:0072325	biolink:NamedThing	vulval cell fate commitment	The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.	got7fsn_ti							mah	2010-11-01T02:02:16Z						biological_process											owl:Class	
GO:0120045	biolink:NamedThing	stereocilium maintenance	The organization process that preserves a stereocilium in a stable functional or structural state.	got7fsn_ti							krc	2017-05-15T20:55:13Z						biological_process											owl:Class	
GO:0009866	biolink:NamedThing	induced systemic resistance, ethylene mediated signaling pathway	The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance.	got7fsn_ti	induced systemic resistance, ethylene mediated signalling pathway|induced systemic resistance, ethene mediated signaling pathway|ethene mediated signaling pathway (induced systemic resistance)|induced systemic resistance, ethene mediated signalling pathway|ethylene mediated signaling pathway (induced systemic resistance)													biological_process											owl:Class	
GO:0004612	biolink:NamedThing	phosphoenolpyruvate carboxykinase (ATP) activity	Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate.	got7fsn_ti	PEPCK (ATP)|ATP:oxaloacetate carboxy-lyase (transphosphorylating)|ATP:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)|phosphopyruvate carboxylase (ATP)|phosphopyruvate carboxykinase|phosphopyruvate carboxykinase (adenosine triphosphate)|phosphoenolpyruvate carboxylase (ATP)|phosphoenolpyruvic carboxykinase|PEPK											EC:4.1.1.49|RHEA:18617|MetaCyc:PEPCARBOXYKIN-RXN|KEGG_REACTION:R00341		molecular_function											owl:Class	
GO:0071541	biolink:NamedThing	eukaryotic translation initiation factor 3 complex, eIF3m	An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m.	got7fsn_ti	eIF3m-containing eukaryotic translation initiation factor 3 complex						mah	2010-01-12T02:26:41Z						cellular_component											owl:Class	
GO:0062189	biolink:NamedThing	anandamide 14,15 epoxidase activity	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							dph	2019-11-26T18:57:55Z				RHEA:53148		molecular_function											owl:Class	
GO:0102685	biolink:NamedThing	UDP-glucose:trans-zeatin 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + trans-zeatin <=> H+ + trans-zeatin-7-N-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-4721		molecular_function											owl:Class	
GO:0030104	biolink:NamedThing	water homeostasis	Any process involved in the maintenance of an internal steady state of water within an organism or cell.	got7fsn_ti	regulation of osmotic pressure|osmoregulation										GO:0018987	Wikipedia:Osmoregulation		biological_process											owl:Class	
GO:0030628	biolink:NamedThing	pre-mRNA 3'-splice site binding	Binding to a pre-mRNA 3' splice site sequence.	got7fsn_ti	pre-mRNA 3' splice site binding													molecular_function											owl:Class	
GO:0070379	biolink:NamedThing	high mobility group box 1 binding	Binding to high mobility group box 1 (HMBGB1).	got7fsn_ti	HMGB1 binding													molecular_function											owl:Class	
GO:0006515	biolink:NamedThing	protein quality control for misfolded or incompletely synthesized proteins	The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.	got7fsn_ti	protein quality control by the ubiquitin-proteasome system|misfolded or incompletely synthesized protein breakdown|misfolded or incompletely synthesized protein degradation|degradation of misfolded or incompletely synthesized proteins|protein quality control (PQC)|misfolded or incompletely synthesized protein catabolism|misfolded or incompletely synthesized protein catabolic process													biological_process											owl:Class	
GO:0021557	biolink:NamedThing	oculomotor nerve development	The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	got7fsn_ti	CN III development|cranial nerve 3 development|cranial nerve III development													biological_process											owl:Class	
GO:0060820	biolink:NamedThing	inactivation of X chromosome by heterochromatin assembly	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.	got7fsn_ti	inactivation of X chromosome by heterochromatin formation						dph	2009-08-11T10:58:06Z						biological_process											owl:Class	
GO:0035575	biolink:NamedThing	histone H4-methyl-lysine-20 demethylase activity	Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone demethylase activity (H4-K20 specific)|histone H4K20me demethylase activity	https://github.com/geneontology/go-ontology/issues/21089					bf	2010-08-13T10:51:13Z				Reactome:R-HSA-2172678		molecular_function											owl:Class	
GO:0007290	biolink:NamedThing	spermatid nucleus elongation	The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation.	got7fsn_ti	spermatid nuclear elongation													biological_process											owl:Class	
GO:0008823	biolink:NamedThing	cupric reductase activity	Catalysis of the reaction: Cu+ + NAD+ + H+ = Cu2+ + NADH.	got7fsn_ti												EC:1.16.1.-|MetaCyc:R170-RXN		molecular_function											owl:Class	
GO:0018834	biolink:NamedThing	dichloromethane dehalogenase activity	Catalysis of the reaction: dichloromethane + H(2)O = 2 chloride + formaldehyde + 2 H(+).	got7fsn_ti	dichloromethane chloride-lyase (chloride-hydrolysing)|dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming)											RHEA:15397|KEGG_REACTION:R00603|UM-BBD_reactionID:r0188|MetaCyc:DICHLOROMETHANE-DEHALOGENASE-RXN|EC:4.5.1.3		molecular_function											owl:Class	
GO:0018104	biolink:NamedThing	peptidoglycan-protein cross-linking	The process of covalently linking peptidoglycan (murein) to proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0009373	biolink:NamedThing	regulation of transcription by pheromones	Any process involving pheromones that modulates the frequency, rate or extent of transcription.	got7fsn_ti														biological_process											owl:Class	
GO:0047127	biolink:NamedThing	thiomorpholine-carboxylate dehydrogenase activity	Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate.	got7fsn_ti	ketimine-reducing enzyme|thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity|ketimine reductase activity											Reactome:R-HSA-5693347|MetaCyc:1.5.1.25-RXN|EC:1.5.1.25		molecular_function											owl:Class	
GO:0034663	biolink:NamedThing	endoplasmic reticulum chaperone complex	A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.	got7fsn_ti	ER chaperone complex|endoplasmic reticulum network complex|ER network complex													cellular_component											owl:Class	
GO:0042252	biolink:NamedThing	establishment of planar polarity of larval imaginal disc epithelium	Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates.	got7fsn_ti														biological_process											owl:Class	
GO:0070024	biolink:NamedThing	CD19-Vav-PIK3R1 complex	A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).	got7fsn_ti	CD19-Vav-PI 3-kinase (p85 subunit) complex													cellular_component											owl:Class	
GO:0046601	biolink:NamedThing	positive regulation of centriole replication	Any process that activates or increases the frequency, rate or extent of centriole replication.	got7fsn_ti	up regulation of centriole replication|up-regulation of centriole replication|activation of centriole replication|upregulation of centriole replication|stimulation of centriole replication													biological_process											owl:Class	
GO:0031078	biolink:NamedThing	histone deacetylase activity (H3-K14 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0046529	biolink:NamedThing	imaginal disc fusion, thorax closure	The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.	got7fsn_ti														biological_process											owl:Class	
GO:0030070	biolink:NamedThing	insulin processing	The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.	got7fsn_ti														biological_process											owl:Class	
GO:0008734	biolink:NamedThing	L-aspartate oxidase activity	Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide.	got7fsn_ti	L-aspartate:oxygen oxidoreductase											RHEA:25876|EC:1.4.3.16|MetaCyc:L-ASPARTATE-OXID-RXN|MetaCyc:RXN-9772		molecular_function											owl:Class	
GO:0031754	biolink:NamedThing	Edg-1 sphingosine 1-phosphate receptor binding	Binding to an Edg-1 sphingosine 1-phosphate receptor.	got7fsn_ti	Edg-1 sphingosine 1-phosphate receptor ligand													molecular_function											owl:Class	
GO:1990938	biolink:NamedThing	peptidyl-aspartic acid autophosphorylation	The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein.	got7fsn_ti	aspartyl autophosphorylation|peptidyl-aspartate autophosphorylation						bf	2016-04-04T10:49:53Z						biological_process											owl:Class	
GO:0033931	biolink:NamedThing	endogalactosaminidase activity	Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).	got7fsn_ti	galactosaminoglycan glycanohydrolase activity											MetaCyc:3.2.1.109-RXN|EC:3.2.1.109		molecular_function											owl:Class	
GO:0071353	biolink:NamedThing	cellular response to interleukin-4	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.	got7fsn_ti	cellular response to IL-4						mah	2009-12-11T02:51:00Z						biological_process											owl:Class	
GO:0008784	biolink:NamedThing	alanine racemase activity	Catalysis of the reaction: L-alanine = D-alanine.	got7fsn_ti	L-alanine racemase activity											RHEA:20249|MetaCyc:ALARACECAT-RXN|KEGG_REACTION:R00401|EC:5.1.1.1		molecular_function											owl:Class	
GO:0009738	biolink:NamedThing	abscisic acid-activated signaling pathway	A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.	got7fsn_ti	ABA signal transduction|abscisic acid signal transduction|ABA signaling|abscisic acid mediated signalling|abscisic acid-mediated signaling pathway													biological_process											owl:Class	
GO:0001877	biolink:NamedThing	lipoarabinomannan immune receptor activity	Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response.	got7fsn_ti	LAM receptor activity|lipoarabinomannan receptor activity													molecular_function											owl:Class	
GO:1990891	biolink:NamedThing	mitotic sister chromatid arm separation	The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis.	got7fsn_ti							mah	2015-11-03T14:01:16Z						biological_process											owl:Class	
GO:1903047	biolink:NamedThing	mitotic cell cycle process	A process that is part of the mitotic cell cycle.	got7fsn_ti							jl	2014-05-22T14:22:34Z						biological_process											owl:Class	
GO:0006543	biolink:NamedThing	glutamine catabolic process	The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid.	got7fsn_ti	glutamine breakdown|glutamine degradation|glutamine catabolism													biological_process											owl:Class	
GO:0014852	biolink:NamedThing	regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0033169	biolink:NamedThing	histone H3-K9 demethylation	The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone.	got7fsn_ti														biological_process											owl:Class	
GO:0070076	biolink:NamedThing	histone lysine demethylation	The modification of a histone by the removal of a methyl group from a lysine residue.	got7fsn_ti														biological_process											owl:Class	
GO:0001002	biolink:NamedThing	RNA polymerase III type 1 promoter sequence-specific DNA binding	Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.	got7fsn_ti	RNA polymerase III type 1 promoter DNA binding						krc	2010-08-18T05:38:20Z			GO:0001030			molecular_function											owl:Class	
GO:0080084	biolink:NamedThing	5S rDNA binding	Binding to a 5S rDNA sequence, encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists.	got7fsn_ti							dhl	2009-04-22T02:32:20Z						molecular_function											owl:Class	
GO:0097562	biolink:NamedThing	left lateral basal body pair	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.	got7fsn_ti					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:09:11Z						cellular_component											owl:Class	
GO:0007516	biolink:NamedThing	hemocyte development	The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.	got7fsn_ti	arthropod blood cell development													biological_process											owl:Class	
GO:0042019	biolink:NamedThing	interleukin-23 binding	Binding to interleukin-23.	got7fsn_ti	IL-23 binding													molecular_function											owl:Class	
GO:0010337	biolink:NamedThing	regulation of salicylic acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid.	got7fsn_ti	regulation of salicylic acid metabolism													biological_process											owl:Class	
GO:0030075	biolink:NamedThing	bacterial thylakoid	A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria.	got7fsn_ti	plasma membrane-derived thylakoid													cellular_component											owl:Class	
GO:0009579	biolink:NamedThing	thylakoid	A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.	got7fsn_ti	photosynthetic membrane				A thylakoid is not considered an organelle, but some thylakoids are part of organelles.							Wikipedia:Thylakoid		cellular_component											owl:Class	
GO:0044195	biolink:NamedThing	nucleoplasmic reticulum	Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport.	got7fsn_ti	nuclear channels						jl	2009-10-20T02:24:09Z						cellular_component											owl:Class	
GO:0019604	biolink:NamedThing	toluene oxidation to catechol	The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2).	got7fsn_ti												UM-BBD_pathwayID:tol|MetaCyc:TOLUENE-DEG-CATECHOL-PWY		biological_process											owl:Class	
GO:0120303	biolink:NamedThing	visually-mediated background adaptation	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20524					krc	2021-02-09T18:35:11Z						biological_process											owl:Class	
GO:0120302	biolink:NamedThing	background adaptation	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20524					krc	2021-02-09T18:11:11Z						biological_process											owl:Class	
GO:0048389	biolink:NamedThing	intermediate mesoderm development	The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.	got7fsn_ti														biological_process											owl:Class	
GO:0001949	biolink:NamedThing	sebaceous gland cell differentiation	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.	got7fsn_ti	sebocytes differentiation													biological_process											owl:Class	
GO:0052628	biolink:NamedThing	4-hydroxybenzoate amino acid synthetase activity	Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate.	got7fsn_ti	4-hydroxybenzoyl amino acid synthetase activity|p-hydroxybenzoyl amino acid synthetase activity|p-hydroxybenzoate amino acid synthetase activity|4HBA amino acid synthetase activity													molecular_function											owl:Class	
GO:0102379	biolink:NamedThing	steviolbioside glucosyltransferase activity (stevioside forming)	Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13514		molecular_function											owl:Class	
GO:0101004	biolink:NamedThing	cytolytic granule membrane	The lipid bilayer surrounding the cytolytic granule.	got7fsn_ti							mec	2015-12-15T04:32:00Z						cellular_component											owl:Class	
GO:0005765	biolink:NamedThing	lysosomal membrane	The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.	got7fsn_ti	lysosome membrane													cellular_component											owl:Class	
GO:0014734	biolink:NamedThing	skeletal muscle hypertrophy	The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.	got7fsn_ti														biological_process											owl:Class	
GO:0043501	biolink:NamedThing	skeletal muscle adaptation	Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.	got7fsn_ti	skeletal muscle plasticity													biological_process											owl:Class	
GO:0018428	biolink:NamedThing	copper incorporation into copper-sulfur cluster	The incorporation of copper into a copper-sulfur cluster.	got7fsn_ti	copper incorporation into copper-sulphur cluster													biological_process											owl:Class	
GO:0000818	biolink:NamedThing	nuclear MIS12/MIND complex	A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1.	got7fsn_ti	Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex|MIND complex													cellular_component											owl:Class	
GO:0000104	biolink:NamedThing	succinate dehydrogenase activity	Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.	got7fsn_ti	succinic acid dehydrogenase activity|fumarate reductase activity|succinic dehydrogenase activity|succinate oxidoreductase activity|succinate:(acceptor) oxidoreductase activity|succinate:acceptor oxidoreductase activity|fumaric hydrogenase activity|succinyl dehydrogenase activity|fumarate dehydrogenase activity|succinodehydrogenase activity										GO:0019739	RHEA:16357|MetaCyc:SUCC-FUM-OXRED-RXN		molecular_function											owl:Class	
GO:0120139	biolink:NamedThing	positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.	got7fsn_ti							krc	2018-03-22T16:24:20Z						biological_process											owl:Class	
GO:0050572	biolink:NamedThing	L-idonate 5-dehydrogenase activity	Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+.	got7fsn_ti	L-idonate:NAD(P)+ oxidoreductase activity											MetaCyc:1.1.1.264-RXN|EC:1.1.1.264		molecular_function											owl:Class	
GO:0035605	biolink:NamedThing	peptidyl-cysteine S-nitrosylase activity	Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.	got7fsn_ti	protein nitrosylase activity|S-nitrosylase activity				This term should not be used to annotate the nitrosylating action of nitric oxide synthase (NOS) if the nitroso group is synthesized directly on the substrate.		bf	2010-11-16T09:49:26Z						molecular_function											owl:Class	
GO:0001823	biolink:NamedThing	mesonephros development	The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.	got7fsn_ti	Wolffian body development													biological_process											owl:Class	
GO:0016493	biolink:NamedThing	C-C chemokine receptor activity	Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.	got7fsn_ti														molecular_function											owl:Class	
GO:0004950	biolink:NamedThing	chemokine receptor activity	Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.	got7fsn_ti														molecular_function											owl:Class	
GO:0034495	biolink:NamedThing	protein storage vacuole lumen	The volume enclosed by the protein storage vacuole membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0035137	biolink:NamedThing	hindlimb morphogenesis	The process in which the anatomical structures of the hindlimb are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0051920	biolink:NamedThing	peroxiredoxin activity	Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.	got7fsn_ti	Prx activity|alkyl hydroperoxide reductase C22 activity|PRDX activity|AhpC activity|thiol-containing-reductant:hydroperoxide oxidoreductase activity				Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:1.11.1.7), which has a different reaction mechanism.							Reactome:R-HSA-1222431|EC:1.11.1.24|Reactome:R-HSA-1222755|Reactome:R-HSA-1500804|RHEA:10008|MetaCyc:1.11.1.15-RXN		molecular_function											owl:Class	
GO:0018439	biolink:NamedThing	peptidyl-L-leucine methyl ester biosynthetic process from peptidyl-leucine	The modification of a C-terminal peptidyl-leucine to form peptidyl-L-leucine methyl ester.	got7fsn_ti	peptidyl-leucine esterification										GO:0018440	RESID:AA0299		biological_process											owl:Class	
GO:0033756	biolink:NamedThing	Oplophorus-luciferin 2-monooxygenase activity	Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.	got7fsn_ti	Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity|Oplophorus luciferase activity											RHEA:20417|MetaCyc:RXN-3361|EC:1.13.12.13		molecular_function											owl:Class	
GO:0016997	biolink:NamedThing	alpha-sialidase activity	Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.	got7fsn_ti														molecular_function											owl:Class	
GO:0098747	biolink:NamedThing	slow, calcium ion-dependent exocytosis of neurotransmitter	The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release.	got7fsn_ti														biological_process											owl:Class	
GO:0048791	biolink:NamedThing	calcium ion-regulated exocytosis of neurotransmitter	The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels.	got7fsn_ti														biological_process											owl:Class	
GO:0002629	biolink:NamedThing	negative regulation of proteolysis associated with antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.	got7fsn_ti	downregulation of proteolysis associated with antigen processing and presentation|down regulation of proteolysis associated with antigen processing and presentation|down-regulation of proteolysis associated with antigen processing and presentation|inhibition of proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0047581	biolink:NamedThing	4-methyleneglutamate-ammonia ligase activity	Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH(4)(+) = 4-methylene-L-glutamine + AMP + diphosphate + 2 H(+).	got7fsn_ti	4-methyleneglutamine synthetase activity|4-methylene-L-glutamate:ammonia ligase (AMP-forming)											EC:6.3.1.7|RHEA:13853|KEGG_REACTION:R02711|MetaCyc:4-METHYLENEGLUTAMATE--AMMONIA-LIGASE-RXN		molecular_function											owl:Class	
GO:0018068	biolink:NamedThing	peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine	The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases.	got7fsn_ti	peptidyl-L-2',4',5'-topaquinone synthesis from peptidyl-tyrosine|peptidyl-L-2',4',5'-topaquinone anabolism from peptidyl-tyrosine|peptidyl-L-2',4',5'-topaquinone formation from peptidyl-tyrosine											RESID:AA0147		biological_process											owl:Class	
GO:0060959	biolink:NamedThing	cardiac neuron development	The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.	got7fsn_ti	heart neuron development						dph	2009-09-30T10:14:56Z						biological_process											owl:Class	
GO:0034325	biolink:NamedThing	O-decanoyltransferase activity	Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0034563	biolink:NamedThing	2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity	Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0867		molecular_function											owl:Class	
GO:0097194	biolink:NamedThing	execution phase of apoptosis	A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.	got7fsn_ti	execution phase of apoptotic process|apoptosis						pr	2011-11-23T09:45:24Z						biological_process											owl:Class	
GO:0009353	biolink:NamedThing	mitochondrial oxoglutarate dehydrogenase complex	A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.	got7fsn_ti					See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.									cellular_component											owl:Class	
GO:0036052	biolink:NamedThing	protein localization to uropod	A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell.	got7fsn_ti	protein localisation to uropod						bf	2011-12-12T10:45:26Z						biological_process											owl:Class	
GO:0042338	biolink:NamedThing	cuticle development involved in collagen and cuticulin-based cuticle molting cycle	Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans.	got7fsn_ti	collagen and cuticulin-based cuticle development during molting|cuticle anabolism during molting|cuticle biosynthetic process during molting|cuticle formation during molting|cuticle synthesis during molting													biological_process											owl:Class	
GO:0070314	biolink:NamedThing	G1 to G0 transition	A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.	got7fsn_ti	cell cycle quiescence|G1/G0 transition|stationary phase|establishment of cell quiescence													biological_process											owl:Class	
GO:0042106	biolink:NamedThing	gamma-delta T cell receptor complex	A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein.	got7fsn_ti	gamma-delta TCR complex|gamma-delta T-lymphocyte receptor complex|gamma-delta T-cell receptor complex|gamma-delta T lymphocyte receptor complex													cellular_component											owl:Class	
GO:0042101	biolink:NamedThing	T cell receptor complex	A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.	got7fsn_ti	TCR complex|T-lymphocyte receptor complex|TCR|T-cell receptor complex|T lymphocyte receptor complex											Wikipedia:T_cell_receptor		cellular_component											owl:Class	
GO:0036034	biolink:NamedThing	mediator complex assembly	The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.	got7fsn_ti							bf	2011-10-31T05:18:11Z						biological_process											owl:Class	
GO:0102229	biolink:NamedThing	amylopectin maltohydrolase activity	Catalysis of the reaction: n H2O + an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin <=> amylopectin + maltose.	got7fsn_ti												EC:3.2.1.2|MetaCyc:RXN-12278		molecular_function											owl:Class	
GO:0016062	biolink:NamedThing	adaptation of rhodopsin mediated signaling	The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation.	got7fsn_ti	adaptation of rhodopsin mediated signalling													biological_process											owl:Class	
GO:0047441	biolink:NamedThing	5-dehydro-2-deoxyphosphogluconate aldolase activity	Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate.	got7fsn_ti	5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (pyruvate-forming)|phospho-5-dehydro-2-deoxygluconate aldolase activity|phospho-5-keto-2-deoxygluconate aldolase activity|5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase activity											RHEA:13177|MetaCyc:4.1.2.29-RXN|EC:4.1.2.29|KEGG_REACTION:R05378		molecular_function											owl:Class	
GO:0071632	biolink:NamedThing	optomotor response	Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.	got7fsn_ti							mah	2010-02-11T04:06:41Z				Wikipedia:Optomotor_response		biological_process											owl:Class	
GO:0007634	biolink:NamedThing	optokinetic behavior	The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus.	got7fsn_ti	optokinetic behaviour													biological_process											owl:Class	
GO:0008131	biolink:NamedThing	primary amine oxidase activity	Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.	got7fsn_ti	primary-amine:oxygen oxidoreductase (deaminating) activity|amine oxidase (copper-containing) activity|amine oxidase activity										GO:0008122|GO:0004041	Reactome:R-HSA-5696146|Reactome:R-HSA-141202|KEGG_REACTION:R01853|Reactome:R-HSA-5696183|Reactome:R-HSA-379382|EC:1.4.3.21|Reactome:R-HSA-379395|MetaCyc:RXN-9597|Reactome:R-HSA-141200|Reactome:R-HSA-5603108|Reactome:R-HSA-141186|Reactome:R-HSA-374909		molecular_function											owl:Class	
GO:0018268	biolink:NamedThing	GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GPI anchor formation via N-glycyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-glycyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-glycyl-glycosylphosphatidylinositolethanolamine											RESID:AA0161		biological_process											owl:Class	
GO:0002554	biolink:NamedThing	serotonin secretion by platelet	The regulated release of serotonin by a platelet or group of platelets.	got7fsn_ti	serotonin release by platelet													biological_process											owl:Class	
GO:0120297	biolink:NamedThing	histone dopaminyltransferase activity	Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20685					krc	2021-01-19T03:17:13Z						molecular_function											owl:Class	
GO:0120296	biolink:NamedThing	peptide dopaminyltransferase activity	Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20685					krc	2021-01-19T02:20:30Z				RHEA:66556		molecular_function											owl:Class	
GO:0018080	biolink:NamedThing	peptidyl-tryptophan bromination	The bromination of peptidyl-tryptophan, to form peptidyl-L-6'-bromotryptophan.	got7fsn_ti												RESID:AA0179		biological_process											owl:Class	
GO:0051434	biolink:NamedThing	BH3 domain binding	Binding to a BH3 protein domain, present in Bcl-2 family members. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.	got7fsn_ti														molecular_function											owl:Class	
GO:0017008	biolink:NamedThing	protein-phycobiliviolin linkage	The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.	got7fsn_ti												RESID:AA0258		biological_process											owl:Class	
GO:0052673	biolink:NamedThing	prenol kinase activity	Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity.	got7fsn_ti	prenol phosphotransferase activity|prenyl alcohol kinase activity|prenyl alcohol phosphotransferase activity						ai	2011-04-11T04:02:23Z						molecular_function											owl:Class	
GO:0003053	biolink:NamedThing	circadian regulation of heart rate	Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.	got7fsn_ti	circadian regulation of heart contraction rate													biological_process											owl:Class	
GO:0010459	biolink:NamedThing	negative regulation of heart rate	Any process that stops, prevents or reduces the frequency or rate of heart contraction.	got7fsn_ti														biological_process											owl:Class	
GO:2000847	biolink:NamedThing	negative regulation of corticosteroid hormone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion.	got7fsn_ti	negative regulation of corticosteroid secretion						bf	2011-07-26T08:43:42Z						biological_process											owl:Class	
GO:0039650	biolink:NamedThing	suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host caspase activity. Caspases are cysteine-type endopeptidases which contribute to the apoptotic process.	got7fsn_ti	inhibition of host caspases by virus						bf	2012-10-09T15:30:48Z						biological_process											owl:Class	
GO:0019050	biolink:NamedThing	suppression by virus of host apoptotic process	Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.	got7fsn_ti	suppression of apoptosis in host by virus|negative regulation by virus of host apoptosis|negative regulation of apoptosis by virus|suppression by virus of host apoptosis													biological_process											owl:Class	
GO:0030263	biolink:NamedThing	apoptotic chromosome condensation	The compaction of chromatin during apoptosis.	got7fsn_ti	pyknosis											Wikipedia:Pyknosis		biological_process											owl:Class	
GO:0030261	biolink:NamedThing	chromosome condensation	The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.	got7fsn_ti	eukaryotic chromosome condensation|DNA condensation|nuclear chromosome condensation										GO:0000068			biological_process											owl:Class	
GO:0045106	biolink:NamedThing	intermediate filament depolymerization	Disassembly of intermediate filaments by the removal of component monomers from a filament.	got7fsn_ti														biological_process											owl:Class	
GO:0071570	biolink:NamedThing	cement gland development	The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed.	got7fsn_ti							mah	2010-01-20T04:31:04Z						biological_process											owl:Class	
GO:0003169	biolink:NamedThing	coronary vein morphogenesis	The process in which the anatomical structures of veins of the heart are generated and organized.	got7fsn_ti							dph	2009-10-08T10:45:41Z						biological_process											owl:Class	
GO:0039642	biolink:NamedThing	virion nucleoid	The region of a virion in which the nucleic acid is confined.	got7fsn_ti							bf	2012-09-07T14:14:52Z						cellular_component											owl:Class	
GO:0060578	biolink:NamedThing	superior vena cava morphogenesis	The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.	got7fsn_ti							dph	2009-05-06T08:47:21Z						biological_process											owl:Class	
GO:0030435	biolink:NamedThing	sporulation resulting in formation of a cellular spore	The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	got7fsn_ti	spore formation|spore biosynthesis|cellular spore formation by sporulation|spore differentiation				Note that the synonym 'spore differentiation', like the term name and definition, refers to differentiation into a spore rather than any subsequent developmental changes that a spore may undergo.							Wikipedia:Sporogenesis		biological_process											owl:Class	
GO:0010813	biolink:NamedThing	neuropeptide catabolic process	The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction.	got7fsn_ti														biological_process											owl:Class	
GO:0102307	biolink:NamedThing	erythromycin C 3''-o-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + erythromycin C <=> S-adenosyl-L-homocysteine  + erythromycin A + H+.	got7fsn_ti												RHEA:32647|EC:2.1.1.254|MetaCyc:RXN-12923		molecular_function											owl:Class	
GO:0002222	biolink:NamedThing	stimulatory killer cell immunoglobulin-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a killer cell immunoglobulin-like receptor capable of cellular activation.	got7fsn_ti	stimulatory KIR signaling pathway|stimulatory killer cell immunoglobulin-like receptor signalling pathway													biological_process											owl:Class	
GO:0002220	biolink:NamedThing	innate immune response activating cell surface receptor signaling pathway	Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor.	got7fsn_ti	innate immune response activating cell surface receptor signalling pathway|activation of innate immune response by cell surface receptor signaling pathway													biological_process											owl:Class	
GO:0015284	biolink:NamedThing	fructose uniporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0045148	biolink:NamedThing	tripeptide aminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a tripeptide.	got7fsn_ti	peptidase B|imidoendopeptidase activity|peptidase T|lymphopeptidase activity|aminotripeptidase activity|alanine-phenylalanine-proline arylamidase activity|aminoexotripeptidase activity	https://github.com/geneontology/go-ontology/issues/19681										MetaCyc:3.4.11.4-RXN|EC:3.4.11.4		molecular_function											owl:Class	
GO:0004177	biolink:NamedThing	aminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681										MetaCyc:3.4.11.5-RXN|Reactome:R-HSA-983162|EC:3.4.11.5|EC:3.4.11.-|EC:3.4.11.9|EC:3.4.11.21|MetaCyc:3.4.11.21-RXN|MetaCyc:3.4.11.6-RXN|MetaCyc:3.4.11.9-RXN|EC:3.4.11.6|MetaCyc:RXN0-5052|Reactome:R-HSA-2534096|Reactome:R-HSA-8851929|Reactome:R-HSA-1236954		molecular_function											owl:Class	
GO:0102151	biolink:NamedThing	3-oxo-myristate decarboxylase activity	Catalysis of the reaction: 3-oxo-myristate + H+ <=> 2-tridecanone + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-11669|EC:4.1.1.56		molecular_function											owl:Class	
GO:0006034	biolink:NamedThing	cuticle chitin metabolic process	The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.	got7fsn_ti	cuticle chitin metabolism													biological_process											owl:Class	
GO:0006030	biolink:NamedThing	chitin metabolic process	The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.	got7fsn_ti	chitin metabolism|beta-1,4-linked N-acetylglucosamine metabolic process|beta-1,4-linked N-acetylglucosamine metabolism													biological_process											owl:Class	
GO:0005685	biolink:NamedThing	U1 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U1, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U1 snRNP, most of which remain associated with the U1 snRNA both while the U1 snRNP is free or assembled into a series of spliceosomal complexes.	got7fsn_ti	snRNP U1													cellular_component											owl:Class	
GO:0047630	biolink:NamedThing	ADP-phosphoglycerate phosphatase activity	Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H(2)O = 3-ADP-glycerate + phosphate.	got7fsn_ti	ADPphosphoglycerate phosphatase activity|3-(ADP)-2-phosphoglycerate phosphohydrolase activity|adenosine diphosphate phosphoglycerate phosphatase activity											RHEA:15861|KEGG_REACTION:R03969|MetaCyc:ADP-PHOSPHOGLYCERATE-PHOSPHATASE-RXN|EC:3.1.3.28		molecular_function											owl:Class	
GO:0005041	biolink:NamedThing	low-density lipoprotein particle receptor activity	Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.	got7fsn_ti	LDL receptor|low-density lipoprotein receptor activity|LDLR activity										GO:0008032	Reactome:R-HSA-2404131|Wikipedia:LDL_receptor|Reactome:R-HSA-2424254		molecular_function											owl:Class	
GO:0030228	biolink:NamedThing	lipoprotein particle receptor activity	Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.	got7fsn_ti	plasma lipoprotein particle receptor activity|lipoprotein receptor activity				This term is intended for cell surface receptors that bind and internalize a lipoprotein particle. For members of the lipoprotein receptor family that transduce a signal rather than endocytose their ligand, consider instead the terms 'signaling receptor activity ; GO:0038023' and its children, or 'reelin receptor activity ; GO:0038025'.									molecular_function											owl:Class	
GO:0018582	biolink:NamedThing	1-hydroxy-2-naphthoate 1,2-dioxygenase activity	Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate.	got7fsn_ti	1-hydroxy-2-naphthoate-degrading enzyme activity|1-hydroxy-2-naphthoate dioxygenase activity|1-hydroxy-2-naphthoic acid dioxygenase activity|1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)											RHEA:14749|EC:1.13.11.38|UM-BBD_reactionID:r0486|MetaCyc:1.13.11.38-RXN		molecular_function											owl:Class	
GO:0061431	biolink:NamedThing	cellular response to methionine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.	got7fsn_ti							dph	2012-02-07T10:27:01Z						biological_process											owl:Class	
GO:0045015	biolink:NamedThing	HDEL sequence binding	Binding to a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.	got7fsn_ti	HDEL receptor activity													molecular_function											owl:Class	
GO:0033897	biolink:NamedThing	ribonuclease T2 activity	Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.	got7fsn_ti	Escherichia coli ribonuclease I' ribonuclease PP2 activity|RNase II activity|RNAase CL activity|RNase T2 activity|ribonucleate 3'-oligonucleotide hydrolase activity|RNase M activity|ribonuclease (non-base specific) activity|ribonucleate nucleotido-2'-transferase (cyclizing) activity|acid ribonuclease activity|ribonnuclease (non-base specific) activity|base-non-specific ribonuclease activity|non-base specific ribonuclease activity|ribonuclease PP3 activity|ribonuclease N2 activity|ribonuclease II activity|ribonuclease U4 activity|nonspecific RNase activity|RNase Ms activity|RNase (non-base specific) activity|nonbase-specific RNase activity|acid RNase activity|ribonuclease M activity|Escherichia coli ribonuclease II activity											EC:4.6.1.19|MetaCyc:3.1.27.1-RXN		molecular_function											owl:Class	
GO:0098619	biolink:NamedThing	selenocysteine-tRNA ligase activity	Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate.	got7fsn_ti												Reactome:R-HSA-2408526		molecular_function											owl:Class	
GO:0033055	biolink:NamedThing	D-arginine metabolic process	The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid.	got7fsn_ti	D-arginine metabolism													biological_process											owl:Class	
GO:0005115	biolink:NamedThing	receptor tyrosine kinase-like orphan receptor binding	Binding to a receptor tyrosine kinase-like orphan receptor (Ror).	got7fsn_ti	Ror ligand|Ror binding|receptor tyrosine kinase-like orphan receptor ligand													molecular_function											owl:Class	
GO:0102662	biolink:NamedThing	malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity	Catalysis of the reaction: 3-oxopropanoate + coenzyme A(4-) + NAD(1-) <=> acetyl-CoA(4-) + carbon dioxide + NADH(2-).	got7fsn_ti												RHEA:22992|MetaCyc:RXN-2902		molecular_function											owl:Class	
GO:0014024	biolink:NamedThing	neural rod cavitation	The process of rod cavitation, which is the formation of a lumen in the neural rod during primary neurulation, producing the neural tube.	got7fsn_ti														biological_process											owl:Class	
GO:0060605	biolink:NamedThing	tube lumen cavitation	The formation of a lumen by hollowing out a solid rod or cord.	got7fsn_ti							dph	2009-05-15T09:39:49Z						biological_process											owl:Class	
GO:0050645	biolink:NamedThing	limonoid glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.	got7fsn_ti	uridine diphosphoglucose-limonoid glucosyltransferase activity|LGTase activity|limonoid UDP-glucosyltransferase activity											EC:2.4.1.210|RHEA:11256|MetaCyc:2.4.1.210-RXN		molecular_function											owl:Class	
GO:0034910	biolink:NamedThing	6-hydroxy-3-succinoylpyridine hydrolase activity	Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine.	got7fsn_ti												UM-BBD_reactionID:r1442		molecular_function											owl:Class	
GO:0001662	biolink:NamedThing	behavioral fear response	An acute behavioral change resulting from a perceived external threat.	got7fsn_ti	behavioural fear response													biological_process											owl:Class	
GO:1990254	biolink:NamedThing	keratin filament binding	Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells.	got7fsn_ti							tb	2013-12-13T22:05:25Z						molecular_function											owl:Class	
GO:0075263	biolink:NamedThing	oogonium development	The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes.	got7fsn_ti														biological_process											owl:Class	
GO:0018417	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide	The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide											RESID:AA0293		biological_process											owl:Class	
GO:0072238	biolink:NamedThing	metanephric long nephron development	The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros.	got7fsn_ti	metanephric juxtamedullary nephron development						mah	2010-03-18T03:48:23Z						biological_process											owl:Class	
GO:0102719	biolink:NamedThing	S-adenosyl-L-methionine:eugenol-O-methyltransferase activity	Catalysis of the reaction: eugenol + S-adenosyl-L-methionine  = H+ + O-methyleugenol + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.146|MetaCyc:RXN-6741		molecular_function											owl:Class	
GO:0052641	biolink:NamedThing	benzoic acid glucosyltransferase activity	Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP.	got7fsn_ti	UDP:glucose:benzoic acid glucosyltransferase activity|benzoate glucosyltransferase activity|UDP:glucose:BA glucosyltransferase activity|UDP:glucose:benzoate glucosyltransferase activity											MetaCyc:RXN-11660		molecular_function											owl:Class	
GO:0004025	biolink:NamedThing	alcohol dehydrogenase activity, iron-dependent	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron.	got7fsn_ti														molecular_function											owl:Class	
GO:0004022	biolink:NamedThing	alcohol dehydrogenase (NAD+) activity	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.	got7fsn_ti	aldehyde dehydrogenase (NAD) activity|yeast alcohol dehydrogenase|NAD-dependent alcohol dehydrogenase|aldo-keto reductase (NAD) activity|alcohol dehydrogenase activity|NADH-aldehyde dehydrogenase|alcohol:NAD+ oxidoreductase|ethanol dehydrogenase|NADH-alcohol dehydrogenase|aliphatic alcohol dehydrogenase|primary alcohol dehydrogenase|ADH|NAD-specific aromatic alcohol dehydrogenase											EC:1.1.1.1|UM-BBD_enzymeID:e0023|Reactome:R-HSA-2162078|MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN|RHEA:10740		molecular_function											owl:Class	
GO:0071927	biolink:NamedThing	octopamine signaling pathway	The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor.	got7fsn_ti	octopamine signalling pathway						mah	2010-09-28T01:18:57Z						biological_process											owl:Class	
GO:0010162	biolink:NamedThing	seed dormancy process	A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.	got7fsn_ti	seed dormancy											Wikipedia:Seed#Seed_dormancy_and_protection		biological_process											owl:Class	
GO:0044096	biolink:NamedThing	type IV pilus	A short filamentous structure on the surface of a bacterial cell distinguished from other pili by post-translational N-methylation of the pilin monomers.	got7fsn_ti	TFP|type IV fimbriae|type 4 pilus						jl	2009-04-22T02:52:55Z						cellular_component											owl:Class	
GO:0047796	biolink:NamedThing	cyclohexane-1,3-dione hydrolase activity	Catalysis of the reaction: cyclohexane-1,3-dione + H(2)O = 5-oxohexanoate + H(+).	got7fsn_ti	cyclohexane-1,3-dione acylhydrolase (decyclizing)|1,3-cyclohexanedione hydrolase activity											EC:3.7.1.10|MetaCyc:CYCLOHEXANE-13-DIONE-HYDROLASE-RXN|RHEA:16473|KEGG_REACTION:R03211		molecular_function											owl:Class	
GO:0061063	biolink:NamedThing	positive regulation of nematode larval development	Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.	got7fsn_ti							dph	2010-03-11T01:03:34Z						biological_process											owl:Class	
GO:0061062	biolink:NamedThing	regulation of nematode larval development	Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.	got7fsn_ti							dph	2010-03-11T12:59:21Z						biological_process											owl:Class	
GO:0072188	biolink:NamedThing	metanephric cap specification	The process in which the metanephric cap acquires its identity.	got7fsn_ti							mah	2010-03-01T01:35:25Z						biological_process											owl:Class	
GO:0072048	biolink:NamedThing	renal system pattern specification	Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system.	got7fsn_ti	renal system pattern formation						mah	2010-01-25T03:31:51Z						biological_process											owl:Class	
GO:0044800	biolink:NamedThing	multi-organism membrane fusion	The membrane organization process that joins two lipid bilayers to form a single membrane, involving more than one organism.	got7fsn_ti							jl	2013-09-10T15:06:11Z						biological_process											owl:Class	
GO:0018597	biolink:NamedThing	ammonia monooxygenase activity	Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions.	got7fsn_ti												EC:1.14.99.39|UM-BBD_enzymeID:e0061|RHEA:27341		molecular_function											owl:Class	
GO:0007441	biolink:NamedThing	anterior midgut (ectodermal) morphogenesis	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0038106	biolink:NamedThing	choriogonadotropin hormone binding	Binding to choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit.	got7fsn_ti	chorionic gonadotropin binding|chorionic gonadotrophin binding						bf	2012-03-08T03:58:40Z						molecular_function											owl:Class	
GO:0045992	biolink:NamedThing	negative regulation of embryonic development	Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.	got7fsn_ti	down regulation of embryonic development|inhibition of embryonic development|down-regulation of embryonic development|downregulation of embryonic development													biological_process											owl:Class	
GO:0046464	biolink:NamedThing	acylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.	got7fsn_ti	acylglycerol catabolism|acylglycerol breakdown|acylglycerol degradation													biological_process											owl:Class	
GO:0046461	biolink:NamedThing	neutral lipid catabolic process	The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity.	got7fsn_ti	neutral lipid degradation|neutral lipid breakdown|neutral lipid catabolism													biological_process											owl:Class	
GO:0048505	biolink:NamedThing	regulation of timing of cell differentiation	The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.	got7fsn_ti	timing of cell differentiation													biological_process											owl:Class	
GO:0006617	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting.	got7fsn_ti	SRP-dependent cotranslational membrane targeting, signal sequence recognition|signal sequence recognition during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational protein-membrane targeting, signal sequence recognition													biological_process											owl:Class	
GO:0034368	biolink:NamedThing	protein-lipid complex remodeling	The acquisition, loss or modification of a protein or lipid within a protein-lipid complex.	got7fsn_ti														biological_process											owl:Class	
GO:0060515	biolink:NamedThing	prostate field specification	The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop.	got7fsn_ti														biological_process											owl:Class	
GO:0048576	biolink:NamedThing	positive regulation of short-day photoperiodism, flowering	Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	got7fsn_ti	up-regulation of short-day photoperiodism, flowering|activation of short-day photoperiodism, flowering|upregulation of short-day photoperiodism, flowering|stimulation of short-day photoperiodism, flowering|up regulation of short-day photoperiodism, flowering													biological_process											owl:Class	
GO:0033748	biolink:NamedThing	hydrogenase (acceptor) activity	Catalysis of the reaction: H2 + A = AH2.	got7fsn_ti	hydrogen:acceptor oxidoreductase activity|hydrogenlyase activity|H2 producing hydrogenase activity|uptake hydrogenase activity|hydrogen:(acceptor) oxidoreductase activity|hydrogen-lyase activity											RHEA:12116|MetaCyc:RXN0-4141|EC:1.12.99.6|MetaCyc:RXN0-5256		molecular_function											owl:Class	
GO:0047637	biolink:NamedThing	alanylphosphatidylglycerol synthase activity	Catalysis of the reaction: L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol.	got7fsn_ti	L-alanyl-tRNA:phosphatidylglycerol alanyltransferase activity|alanyl phosphatidylglycerol synthetase activity|O-alanylphosphatidylglycerol synthase activity											MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN|RHEA:20489|EC:2.3.2.11		molecular_function											owl:Class	
GO:0086067	biolink:NamedThing	AV node cell to bundle of His cell communication	The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti	atrioventricular node cell to bundle of His cell communication						dph	2011-11-22T09:11:44Z						biological_process											owl:Class	
GO:0090722	biolink:NamedThing	receptor-receptor interaction	The aggregation, arrangement and bonding together of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger to form a higher level receptor complex. The formation of the higher level complex initiates a change in cell function.	got7fsn_ti	hetero-receptor complex formation						tb	2016-11-11T17:41:56Z						molecular_function											owl:Class	
GO:0021622	biolink:NamedThing	oculomotor nerve morphogenesis	The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	got7fsn_ti	CN III morphogenesis													biological_process											owl:Class	
GO:1901597	biolink:NamedThing	response to carbendazim	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.	got7fsn_ti							mah	2012-11-07T17:17:06Z						biological_process											owl:Class	
GO:1900768	biolink:NamedThing	fonsecin catabolic process	The chemical reactions and pathways resulting in the breakdown of fonsecin.	got7fsn_ti	fonsecin degradation|fonsecin breakdown|fonsecin catabolism						di	2012-06-04T09:21:38Z						biological_process											owl:Class	
GO:0102785	biolink:NamedThing	violaxanthin oxygenase activity	Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.	got7fsn_ti												MetaCyc:RXN-7886		molecular_function											owl:Class	
GO:0006962	biolink:NamedThing	male-specific antibacterial humoral response	An immune response against bacteria, specific to males and mediated through a body fluid.	got7fsn_ti														biological_process											owl:Class	
GO:0050831	biolink:NamedThing	male-specific defense response to bacterium	A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism.	got7fsn_ti	male-specific defence response to bacterium|male-specific defense response to bacteria|male-specific antibacterial peptide activity|male-specific defence response to bacteria													biological_process											owl:Class	
GO:0051467	biolink:NamedThing	detection of steroid hormone stimulus	The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0099508	biolink:NamedThing	voltage-gated ion channel activity involved in regulation of presynaptic membrane potential	Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.	got7fsn_ti	voltage-dependent ion channel activity involved in regulation of pre-synaptic membrane potential|voltage-dependent ion channel activity involved in regulation of presynaptic membrane potential|voltage-gated ion channel activity involved in regulation of pre-synaptic membrane potential|voltage gated ion channel activity involved in regulation of presynaptic membrane potential													molecular_function											owl:Class	
GO:0005244	biolink:NamedThing	voltage-gated ion channel activity	Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-dependent ion channel activity|voltage gated ion channel activity													molecular_function											owl:Class	
GO:0047766	biolink:NamedThing	carbamoyl-serine ammonia-lyase activity	Catalysis of the reaction: O-carbamoyl-L-serine + H(2)O + H(+) = CO(2) + 2 NH(4)(+) + pyruvate.	got7fsn_ti	O-carbamoyl-L-serine deaminase activity|carbamoylserine deaminase activity|O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming)|O-carbamoyl-L-serine ammonia-lyase (pyruvate-forming)											RHEA:15445|KEGG_REACTION:R00213|MetaCyc:CARBAMOYL-SERINE-AMMONIA-LYASE-RXN|EC:4.3.1.13		molecular_function											owl:Class	
GO:0003963	biolink:NamedThing	RNA-3'-phosphate cyclase activity	Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate.	got7fsn_ti	RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming)|RNA 3'-terminal phosphate cyclase activity|RNA cyclase activity											MetaCyc:RNA-3-PHOSPHATE-CYCLASE-RXN|RHEA:23976|EC:6.5.1.4		molecular_function											owl:Class	
GO:0102591	biolink:NamedThing	delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-15352		molecular_function											owl:Class	
GO:2000076	biolink:NamedThing	positive regulation of cytokinesis, site selection	Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis.	got7fsn_ti	positive regulation of site selection involved in cell cycle cytokinesis						tb	2010-08-27T11:19:58Z						biological_process											owl:Class	
GO:0032467	biolink:NamedThing	positive regulation of cytokinesis	Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.	got7fsn_ti	up-regulation of cytokinesis|upregulation of cytokinesis|positive regulation of cell cycle cytokinesis|stimulation of cytokinesis|activation of cytokinesis|up regulation of cytokinesis										GO:0071777			biological_process											owl:Class	
GO:0032157	biolink:NamedThing	prospore contractile ring	A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis.	got7fsn_ti	meiotic contractile ring|cytokinetic ring|actomyosin ring													cellular_component											owl:Class	
GO:0110086	biolink:NamedThing	meiotic actomyosin contractile ring	A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In fungal cells, the meiotic contractile ring forms beneath the plasma membrane of the prospore envelope in preparation for completing cytokinesis.	got7fsn_ti							kmv	2018-02-12T17:26:17Z						cellular_component											owl:Class	
GO:0044016	biolink:NamedThing	histone acetyltransferase activity (H3-K4 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K4 specific)													molecular_function											owl:Class	
GO:0102199	biolink:NamedThing	nitric oxide reductase activity (NAD(P)H-dependent) activity	Catalysis of the reaction: dinitrogen oxide + H2O + NAD(P) = 2 nitric oxide + H+ + NAD(P)H.	got7fsn_ti												EC:1.7.1.14|MetaCyc:RXN-12112		molecular_function											owl:Class	
GO:0009014	biolink:NamedThing	succinyl-diaminopimelate desuccinylase activity	Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate.	got7fsn_ti	N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase activity|N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase activity											RHEA:22608|MetaCyc:SUCCDIAMINOPIMDESUCC-RXN|EC:3.5.1.18|KEGG_REACTION:R02734		molecular_function											owl:Class	
GO:0016286	biolink:NamedThing	small conductance calcium-activated potassium channel activity	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	got7fsn_ti	SK KCa channels|small conductance KCa channels|SK calcium-activated potassium channel activity													molecular_function											owl:Class	
GO:0060104	biolink:NamedThing	surface coat of collagen and cuticulin-based cuticle extracellular matrix	An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans.	got7fsn_ti	surface coat of collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0080076	biolink:NamedThing	caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a caffeoyl CoA molecule.	got7fsn_ti							dhl	2009-04-14T03:55:49Z						molecular_function											owl:Class	
GO:1990001	biolink:NamedThing	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process.	got7fsn_ti							pr	2012-12-05T15:42:50Z						biological_process											owl:Class	
GO:0097340	biolink:NamedThing	inhibition of cysteine-type endopeptidase activity	Any process that prevents the activation of an inactive cysteine-type endopeptidase.	got7fsn_ti	inhibition of caspase activity|prevention of cysteine-type endopeptidase activity|prevention of caspase activity						pr	2012-06-18T11:23:05Z						biological_process											owl:Class	
GO:0019780	biolink:NamedThing	FAT10 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti														molecular_function											owl:Class	
GO:0004148	biolink:NamedThing	dihydrolipoyl dehydrogenase activity	Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.	got7fsn_ti	dehydrolipoate dehydrogenase activity|glycine-cleavage system L-protein activity|lipoamide oxidoreductase (NADH) activity|lipoamide dehydrogenase (NADH) activity|LDP-Val activity|protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase|lipoamide reductase (NADH) activity|dihydrothioctic dehydrogenase activity|dihydrolipoylprotein reduction|dihydrolipoamide dehydrogenase activity|protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase|lipoate dehydrogenase activity|lipoyl dehydrogenase activity|lipoamide reductase activity|dihydrolipoamide reduction|lipoic acid dehydrogenase activity|diaphorase activity|dihydrolipoamide:NAD+ oxidoreductase|LDP-Glc activity|L-protein activity|dihydrolipoic dehydrogenase activity|E3 component of alpha-ketoacid dehydrogenase complexes activity											Reactome:R-HSA-5694018|MetaCyc:DIHYDLIPOXN-RXN|EC:1.8.1.4|RHEA:15045|Reactome:R-HSA-1222412		molecular_function											owl:Class	
GO:0046724	biolink:NamedThing	oxalic acid secretion	The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.	got7fsn_ti	oxalate secretion													biological_process											owl:Class	
GO:0061225	biolink:NamedThing	mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development	The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.	got7fsn_ti	mesonephric Goormaghtigh proliferation|mesonephric lacis cell proliferation						dph	2010-08-19T01:34:59Z						biological_process											owl:Class	
GO:0033998	biolink:NamedThing	inulin fructotransferase (DFA-III-forming) activity	Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.	got7fsn_ti	inulin fructotransferase (depolymerizing, difructofuranose-1,2':2,3'-dianhydride-forming) activity|inulinase II activity|inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-forming) activity|inulin fructotransferase (depolymerizing) activity|inulin fructotransferase (DFA-III-producing) activity|inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride) activity|2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,3'-dianhydride-forming) activity|inulase II activity											MetaCyc:4.2.2.18-RXN|EC:4.2.2.18		molecular_function											owl:Class	
GO:0009772	biolink:NamedThing	photosynthetic electron transport in photosystem II	A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I.	got7fsn_ti														biological_process											owl:Class	
GO:0009767	biolink:NamedThing	photosynthetic electron transport chain	A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient.	got7fsn_ti	photosynthetic electron transport in plastocyanin|photosynthetic electron transport in cytochrome b6/f|photosynthetic electron transport in plastoquinone|electron carrier, chlorophyll electron transport system										GO:0009776|GO:0009774|GO:0009775			biological_process											owl:Class	
GO:0034905	biolink:NamedThing	5-chloro-4-hydroxy-2-oxopentanate aldolase activity	Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde.	got7fsn_ti												UM-BBD_reactionID:r1437|EC:4.1.3.-		molecular_function											owl:Class	
GO:0048058	biolink:NamedThing	compound eye corneal lens development	The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.	got7fsn_ti														biological_process											owl:Class	
GO:1900081	biolink:NamedThing	regulation of arginine catabolic process	Any process that modulates the frequency, rate or extent of arginine catabolic process.	got7fsn_ti	regulation of arginine breakdown|regulation of arginine degradation|regulation of arginine catabolism						pr	2012-02-01T04:04:39Z						biological_process											owl:Class	
GO:0033241	biolink:NamedThing	regulation of cellular amine catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.	got7fsn_ti	regulation of amine catabolism|regulation of amine breakdown|regulation of amine degradation													biological_process											owl:Class	
GO:0047131	biolink:NamedThing	saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity	Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = L-glutamate + allysine + H(+) + NADH.	got7fsn_ti	dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming)|aminoadipic semialdehyde synthase activity|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)|saccharopin dehydrogenase activity|NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and glutamate forming)											MetaCyc:1.5.1.9-RXN|EC:1.5.1.9|Reactome:R-HSA-70940|KEGG_REACTION:R02313|RHEA:24520		molecular_function											owl:Class	
GO:0019774	biolink:NamedThing	proteasome core complex, beta-subunit complex	The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.	got7fsn_ti														cellular_component											owl:Class	
GO:0060880	biolink:NamedThing	cell morphogenesis involved in semicircular canal fusion	The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.	got7fsn_ti							dph	2009-08-13T10:13:25Z						biological_process											owl:Class	
GO:0031356	biolink:NamedThing	intrinsic component of chloroplast inner membrane	The component of the chloroplast inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to chloroplast inner membrane													cellular_component											owl:Class	
GO:0038038	biolink:NamedThing	G protein-coupled receptor homodimeric complex	A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor.	got7fsn_ti	GPCR homodimer|G-protein coupled receptor homodimeric complex|G-protein coupled receptor homodimer						bf	2011-11-02T04:43:53Z						cellular_component											owl:Class	
GO:0050788	biolink:NamedThing	sequestering of mercury	The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.	got7fsn_ti	sequestration of mercuric ion (Hg2+)|mercury (Hg) ion sequestering|mercury (Hg2+) ion storage|sequestering of mercuric ion (Hg2+)|retention of mercury (Hg2+) ion|mercuric ion (Hg2+) sequestering|mercuric ion (Hg2+) sequestration|sequestration of mercury (Hg) ion|storage of mercury (Hg2+) ion|mercury (Hg2+) ion retention|sequestering of mercury (Hg) ion|mercury (Hg) ion sequestration													biological_process											owl:Class	
GO:0051238	biolink:NamedThing	sequestering of metal ion	The process of binding or confining metal ions such that they are separated from other components of a biological system.	got7fsn_ti	metal ion storage|retention of metal ion|metal ion retention|metal ion sequestration|storage of metal ion|sequestration of metal ion|metal ion sequestering													biological_process											owl:Class	
GO:0098670	biolink:NamedThing	entry receptor-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration.	got7fsn_ti	viral attachment to host entry receptor						dos	2017-01-16T13:18:27Z				VZ:3942		biological_process											owl:Class	
GO:0046813	biolink:NamedThing	receptor-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.	got7fsn_ti	virion attachment, binding of host cell surface receptor													biological_process											owl:Class	
GO:0050817	biolink:NamedThing	coagulation	The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.	got7fsn_ti	clotting													biological_process											owl:Class	
GO:0102653	biolink:NamedThing	gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A51 + 2-oxoglutarate + O2 <=> H+ + gibberellin A51-catabolite + succinate + carbon dioxide + H2O.	got7fsn_ti												MetaCyc:RXN-172		molecular_function											owl:Class	
GO:0021544	biolink:NamedThing	subpallium development	The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.	got7fsn_ti														biological_process											owl:Class	
GO:0035485	biolink:NamedThing	adenine/guanine mispair binding	Binding to a double-stranded DNA region containing an A/G mispair.	got7fsn_ti	G/A mispair binding|A/G mispair binding|guanine-adenine mispair binding						bf	2010-04-23T10:55:43Z						molecular_function											owl:Class	
GO:0102077	biolink:NamedThing	oleamide hydrolase activity	Catalysis of the reaction: oleamide + H2O <=> oleate + ammonium.	got7fsn_ti												RHEA:26506|EC:3.5.1.99|MetaCyc:RXN-10756		molecular_function											owl:Class	
GO:0005780	biolink:NamedThing	extrinsic component of intraperoxisomal membrane	The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	intra-peroxisomal peripheral membrane|extrinsic to intraperoxisomal membrane													cellular_component											owl:Class	
GO:0047583	biolink:NamedThing	4-methyloxaloacetate esterase activity	Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H(2)O = H(+) + methanol + oxaloacetate.	got7fsn_ti	oxaloacetate-4-methyl-ester oxaloacetohydrolase activity											RHEA:10564|MetaCyc:4-METHYLOXALOACETATE-ESTERASE-RXN|KEGG_REACTION:R01144|EC:3.1.1.44		molecular_function											owl:Class	
GO:0003845	biolink:NamedThing	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity	Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+).	got7fsn_ti	corticosteroid 11-reductase|11beta-hydroxysteroid dehydrogenase|11beta-hydroxy steroid dehydrogenase|corticosteroid 11beta-dehydrogenase|beta-hydroxysteroid dehydrogenase	https://github.com/geneontology/go-ontology/issues/21915										MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN|Reactome:R-HSA-194023|Wikipedia:11beta-hydroxysteroid_dehydrogenase		molecular_function											owl:Class	
GO:0047351	biolink:NamedThing	guanosine-triphosphate guanylyltransferase activity	Catalysis of the reaction: 2 GTP = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H(+).	got7fsn_ti	GTP:GTP guanylyltransferase activity											EC:2.7.7.45|MetaCyc:2.7.7.45-RXN|RHEA:18153|KEGG_REACTION:R00012		molecular_function											owl:Class	
GO:0061112	biolink:NamedThing	negative regulation of bud outgrowth involved in lung branching	Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching.	got7fsn_ti							dph	2010-05-05T11:20:42Z						biological_process											owl:Class	
GO:0061048	biolink:NamedThing	negative regulation of branching involved in lung morphogenesis	Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.	got7fsn_ti							dph	2010-02-25T10:51:31Z						biological_process											owl:Class	
GO:0007272	biolink:NamedThing	ensheathment of neurons	The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.	got7fsn_ti	ionic insulation of neurons by glial cells													biological_process											owl:Class	
GO:0021711	biolink:NamedThing	cerebellar unipolar brush cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0060780	biolink:NamedThing	intercalary leaflet morphogenesis	The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.	got7fsn_ti							dph	2009-07-25T07:20:46Z						biological_process											owl:Class	
GO:0043505	biolink:NamedThing	CENP-A containing nucleosome	A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).	got7fsn_ti	centromeric nucleosome|centromere-specific nucleosome|CenH3 containing nucleosome|CNP-T-W-S-X complex|CENP-S-T-W-X|centromere specific nucleosome													cellular_component											owl:Class	
GO:0000786	biolink:NamedThing	nucleosome	A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.	got7fsn_ti	nuclear nucleosome|cytoplasmic nucleosome										GO:0000787|GO:0000788|GO:0005718	Wikipedia:Nucleosome		cellular_component											owl:Class	
GO:0034471	biolink:NamedThing	ncRNA 5'-end processing	Any process involved in forming the mature 5' end of a non-coding RNA molecule.	got7fsn_ti	ncRNA 5' end processing													biological_process											owl:Class	
GO:0035752	biolink:NamedThing	lysosomal lumen pH elevation	Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.	got7fsn_ti	lysosome pH elevation						bf	2011-03-23T10:24:24Z						biological_process											owl:Class	
GO:0019429	biolink:NamedThing	fluorene catabolic process	The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.	got7fsn_ti	fluorene degradation|fluorene metabolic process|fluorene breakdown|fluorene catabolism|fluorene metabolism										GO:0018917	UM-BBD_pathwayID:flu|MetaCyc:FLUORENE-DEG-9-ONE-PWY		biological_process											owl:Class	
GO:0031547	biolink:NamedThing	brain-derived neurotrophic factor receptor signaling pathway	The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.	got7fsn_ti	BDNF signalling pathway|BDNF receptor signaling pathway|brain-derived neurotrophic factor receptor signalling pathway													biological_process											owl:Class	
GO:0008531	biolink:NamedThing	riboflavin kinase activity	Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+).	got7fsn_ti	FK|flavokinase activity|riboflavin kinase (phosphorylating)|ATP:riboflavin 5'-phosphotransferase activity|riboflavine kinase activity											KEGG_REACTION:R00549|RHEA:14357|EC:2.7.1.26|MetaCyc:RIBOFLAVINKIN-RXN|Reactome:R-HSA-196964		molecular_function											owl:Class	
GO:0042259	biolink:NamedThing	peptidyl-L-beta-methylthioasparagine biosynthetic process from peptidyl-asparagine	The modification of peptidyl-asparagine to form peptidyl-L-beta-methylthioasparagine, typical of bacterial ribosomal protein S12.	got7fsn_ti	peptidyl-L-beta-methylthioasparagine synthesis from peptidyl-asparagine|peptidyl-L-beta-methylthioasparagine formation from peptidyl-asparagine|peptidyl-L-beta-methylthioasparagine anabolism from peptidyl-asparagine											RESID:AA0320		biological_process											owl:Class	
GO:0030592	biolink:NamedThing	DNA ADP-ribosylation	The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16614												biological_process											owl:Class	
GO:0002699	biolink:NamedThing	positive regulation of immune effector process	Any process that activates or increases the frequency, rate, or extent of an immune effector process.	got7fsn_ti	activation of immune effector process|upregulation of immune effector process|up-regulation of immune effector process|stimulation of immune effector process|up regulation of immune effector process													biological_process											owl:Class	
GO:0048363	biolink:NamedThing	mucilage pectin metabolic process	The chemical reactions and pathways involving the pectin component of mucilage.	got7fsn_ti	mucilage pectin metabolism													biological_process											owl:Class	
GO:0045488	biolink:NamedThing	pectin metabolic process	The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge.	got7fsn_ti	pectin metabolism													biological_process											owl:Class	
GO:0052630	biolink:NamedThing	UDP-N-acetylgalactosamine diphosphorylase activity	Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine.	got7fsn_ti	N-acetylgalactosamine 1-phosphate uridylyltransferase|uridine diphosphoacetylgalactosamine phosphorylase activity|uridine diphosphoacetylgalactosamine pyrophosphorylase activity|UDP-GalNAc pyrophosphorylase activity|UTP:N-acetyl-alpha-D-galactosamine-1-phosphate uridylyltransferase activity|uridine diphosphate-N-acetylgalactosamine pyrophosphorylase activity|UDP-acetylgalactosamine pyrophosphorylase activity|UTP:2-acetamido-2-deoxy-alpha-D-galactose-1-phosphate uridylyltransferase activity|UDP-N-acetylgalactosamine pyrophosphorylase activity|N-acetylgalactosamine-1-phosphate uridyltransferase activity											RHEA:34363|EC:2.7.7.83		molecular_function											owl:Class	
GO:0043591	biolink:NamedThing	endospore external encapsulating structure	The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer.	got7fsn_ti	peptidoglycan-based spore wall|spore wall|endospore wall										GO:0055030			cellular_component											owl:Class	
GO:0005782	biolink:NamedThing	peroxisomal matrix	The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.	got7fsn_ti	peroxisomal lumen										GO:0031909			cellular_component											owl:Class	
GO:0031907	biolink:NamedThing	microbody lumen	The volume enclosed by the membranes of a microbody.	got7fsn_ti														cellular_component											owl:Class	
GO:0044588	biolink:NamedThing	laminaribiose binding	Binding to laminaribiose, a disaccharide.	got7fsn_ti							jl	2012-04-26T01:19:40Z						molecular_function											owl:Class	
GO:0070492	biolink:NamedThing	oligosaccharide binding	Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	got7fsn_ti														molecular_function											owl:Class	
GO:0106254	biolink:NamedThing	lipid sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of a lipid.	got7fsn_ti							hjd	2020-03-09T17:36:09Z						molecular_function											owl:Class	
GO:0140299	biolink:NamedThing	small molecule sensor activity	Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.	got7fsn_ti	small molecular sensor activity						pg	2018-12-10T14:30:28Z						molecular_function											owl:Class	
GO:0005967	biolink:NamedThing	mitochondrial pyruvate dehydrogenase complex	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase.	got7fsn_ti	pyruvate dehydrogenase complex (lipoamide)				Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.									cellular_component											owl:Class	
GO:0009701	biolink:NamedThing	isoflavonoid phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.	got7fsn_ti	isoflavonoid phytoalexin synthesis|isoflavonoid phytoalexin biosynthesis|isoflavonoid phytoalexin anabolism|isoflavonoid phytoalexin formation													biological_process											owl:Class	
GO:0009717	biolink:NamedThing	isoflavonoid biosynthetic process	The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.	got7fsn_ti	isoflavonoid biosynthesis|isoflavonoid anabolism|isoflavonoid formation|isoflavonoid synthesis													biological_process											owl:Class	
GO:0000092	biolink:NamedThing	mitotic anaphase B	The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0000090	biolink:NamedThing	mitotic anaphase	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0050293	biolink:NamedThing	steroid-lactonase activity	Catalysis of the reaction: H(2)O + testololactone = H(+) + testolate.	got7fsn_ti	testololactone lactonohydrolase activity											KEGG_REACTION:R03641|RHEA:13721|EC:3.1.1.37|MetaCyc:STEROID-LACTONASE-RXN		molecular_function											owl:Class	
GO:0000301	biolink:NamedThing	retrograde transport, vesicle recycling within Golgi	The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi.	got7fsn_ti	retrograde (vesicle recycling within Golgi) transport													biological_process											owl:Class	
GO:0006891	biolink:NamedThing	intra-Golgi vesicle-mediated transport	The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).	got7fsn_ti	intra-Golgi transport													biological_process											owl:Class	
GO:0018609	biolink:NamedThing	chlorobenzene dioxygenase activity	Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).	got7fsn_ti												UM-BBD_enzymeID:e0062|EC:1.14.12.-		molecular_function											owl:Class	
GO:0033486	biolink:NamedThing	delphinidin 3-O-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.	got7fsn_ti	delphinidin 3-O-glucoside formation|delphinidin 3-O-glucoside synthesis|delphinidin 3-O-glucoside anabolism|delphinidin 3-O-glucoside biosynthesis											MetaCyc:PWY-5153		biological_process											owl:Class	
GO:0043583	biolink:NamedThing	ear development	The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.	got7fsn_ti	hearing organ development													biological_process											owl:Class	
GO:0050201	biolink:NamedThing	fucokinase activity	Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+).	got7fsn_ti	fucokinase (phosphorylating) activity|L-fucose kinase activity|ATP:6-deoxy-L-galactose 1-phosphotransferase activity|ATP:beta-L-fucose 1-phosphotransferase activity|fucose kinase activity|L-fucokinase activity											Reactome:R-HSA-6787540|MetaCyc:FUCOKINASE-RXN|EC:2.7.1.52|RHEA:13241|KEGG_REACTION:R03161		molecular_function											owl:Class	
GO:0060586	biolink:NamedThing	multicellular organismal iron ion homeostasis	Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism.	got7fsn_ti							dph	2009-05-08T02:18:21Z						biological_process											owl:Class	
GO:0055072	biolink:NamedThing	iron ion homeostasis	Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.	got7fsn_ti	iron homeostasis													biological_process											owl:Class	
GO:1990929	biolink:NamedThing	sulfoquinovosidase activity	Catalyzes the hydrolysis of terminal non-reducing alpha-sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol, generating alpha-sulfoquinovose.	got7fsn_ti							tb	2016-02-19T01:18:37Z						molecular_function											owl:Class	
GO:0033011	biolink:NamedThing	perinuclear theca	A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0044836	biolink:NamedThing	D-xylose fermentation	The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP.	got7fsn_ti							jl	2014-02-19T16:14:57Z						biological_process											owl:Class	
GO:0033766	biolink:NamedThing	2-hydroxyquinoline 8-monooxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol.	got7fsn_ti	2-oxo-1,2-dihydroquinoline 8-monooxygenase activity|quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating) activity											KEGG_REACTION:R05158|MetaCyc:1.14.13.61-RXN|EC:1.14.13.61|RHEA:22080		molecular_function											owl:Class	
GO:0061987	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter by glucose	Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.	got7fsn_ti							dph	2018-02-15T17:48:00Z						biological_process											owl:Class	
GO:0071447	biolink:NamedThing	cellular response to hydroperoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.	got7fsn_ti							mah	2009-12-16T04:16:42Z						biological_process											owl:Class	
GO:0002510	biolink:NamedThing	central B cell tolerance induction	Tolerance induction of B cells in the bone marrow.	got7fsn_ti	central B-cell tolerance induction|central B-lymphocyte tolerance induction|central B lymphocyte tolerance induction													biological_process											owl:Class	
GO:0002514	biolink:NamedThing	B cell tolerance induction	A process involving any mechanism for tolerance induction in B cells.	got7fsn_ti	B-cell tolerance induction|B lymphocyte tolerance induction|B-lymphocyte tolerance induction													biological_process											owl:Class	
GO:0031646	biolink:NamedThing	positive regulation of nervous system process	Any process that activates or increases the frequency, rate or extent of a neurophysiological process.	got7fsn_ti	activation of neurological process|up regulation of neurological process|positive regulation of neurological process|stimulation of neurological process|up-regulation of neurological process|upregulation of neurological process|positive regulation of neurophysiological process|positive regulation of neurological system process													biological_process											owl:Class	
GO:0005893	biolink:NamedThing	interleukin-2 receptor complex	A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits.	got7fsn_ti	IL-2 receptor complex													cellular_component											owl:Class	
GO:0071477	biolink:NamedThing	cellular hypotonic salinity response	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti	cellular response to hypotonic salt stress						mah	2009-12-18T11:53:20Z						biological_process											owl:Class	
GO:0004662	biolink:NamedThing	CAAX-protein geranylgeranyltransferase activity	Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families.	got7fsn_ti	GGTase-I activity|type I protein geranyl-geranyltransferase activity|GGTaseI activity|protein geranylgeranyltransferase type I|geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity|geranylgeranyltransferase type I activity											MetaCyc:2.5.1.60-RXN|EC:2.5.1.59|MetaCyc:RXN-3701		molecular_function											owl:Class	
GO:0032458	biolink:NamedThing	slow endocytic recycling	The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.	got7fsn_ti														biological_process											owl:Class	
GO:1900619	biolink:NamedThing	acetate ester metabolic process	The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.	got7fsn_ti	acetyl ester metabolism|acetate ester metabolism|acetyl ester metabolic process						bf	2012-05-16T12:29:51Z						biological_process											owl:Class	
GO:1990521	biolink:NamedThing	m7G(5')pppN diphosphatase activator activity	Binds to and increases the activity of m7G(5')pppN diphosphatase.	got7fsn_ti							vw	2014-10-23T11:20:56Z						molecular_function											owl:Class	
GO:0008068	biolink:NamedThing	extracellularly glutamate-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when  glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	got7fsn_ti	extracellular-glutamate-gated chloride channel activity				Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'.									molecular_function											owl:Class	
GO:0005234	biolink:NamedThing	extracellularly glutamate-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when glutamate is  bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	got7fsn_ti	extracellular-glutamate-gated ion channel activity				Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'.									molecular_function											owl:Class	
GO:0002315	biolink:NamedThing	marginal zone B cell differentiation	The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL).	got7fsn_ti	marginal zone B cell development|marginal zone B-lymphocyte differentiation|marginal zone B lymphocyte differentiation|marginal zone B-cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1990098	biolink:NamedThing	core primosome complex	A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication.	got7fsn_ti	core primosome				The core primosome refers to a helicase-primase complex, and should not be confused with the more general GO term 'primosome complex ; GO:1990077'.		bhm	2013-05-14T10:30:02Z						cellular_component											owl:Class	
GO:0090704	biolink:NamedThing	nicotinate-O-glucosyltransferase activity	Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP.	got7fsn_ti							tb	2016-09-21T12:46:21Z						molecular_function											owl:Class	
GO:0140656	biolink:NamedThing	endodeoxyribonuclease activator activity	Binds to and increases the activity of an endodeoxyribonuclease.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21574					pg	2021-06-10T13:31:54Z						molecular_function											owl:Class	
GO:0000727	biolink:NamedThing	double-strand break repair via break-induced replication	The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.	got7fsn_ti														biological_process											owl:Class	
GO:0102433	biolink:NamedThing	phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity	Catalysis of the reaction: L-phenylalanine  + O2 + an N10-formyl-tetrahydrofolate <=> L-tyrosine  + a 10-formyltetrahydrofolate-4a-carbinolamine.	got7fsn_ti												MetaCyc:RXN-13907		molecular_function											owl:Class	
GO:0044390	biolink:NamedThing	ubiquitin-like protein conjugating enzyme binding	Binding to a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme.	got7fsn_ti	E2 protein ligase binding|small protein conjugating enzyme binding						jl	2011-12-15T04:38:44Z						molecular_function											owl:Class	
GO:0050477	biolink:NamedThing	acyl-lysine deacylase activity	Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate.	got7fsn_ti	N6-acyl-L-lysine amidohydrolase activity|6-N-acyl-L-lysine amidohydrolase activity|epsilon-lysine acylase activity											MetaCyc:ACYL-LYSINE-DEACYLASE-RXN|EC:3.5.1.17|RHEA:24548		molecular_function											owl:Class	
GO:0019075	biolink:NamedThing	virus maturation	The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release.	got7fsn_ti	viral maturation|bacteriophage maturation													biological_process											owl:Class	
GO:0019168	biolink:NamedThing	2-octaprenylphenol hydroxylase activity	Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O.	got7fsn_ti												RHEA:27790|MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN		molecular_function											owl:Class	
GO:0032011	biolink:NamedThing	ARF protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state.	got7fsn_ti														biological_process											owl:Class	
GO:0034855	biolink:NamedThing	4-AD 9alpha-hydroxylase activity	Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O.	got7fsn_ti												UM-BBD_reactionID:r1153|EC:1.14.15.-		molecular_function											owl:Class	
GO:0047642	biolink:NamedThing	aldose beta-D-fructosyltransferase activity	Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside.	got7fsn_ti	alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase activity|aldose b-D-fructosyltransferase activity											MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN|EC:2.4.1.162		molecular_function											owl:Class	
GO:0050738	biolink:NamedThing	fructosyltransferase activity	Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0016621	biolink:NamedThing	cinnamoyl-CoA reductase activity	Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+.	got7fsn_ti	ferulyl-CoA reductase activity|cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)|p-hydroxycinnamoyl coenzyme A reductase activity|cinnamoyl CoA reductase activity|cinnamoyl-CoA:NADPH reductase activity|feruloyl-CoA reductase activity|cinnamoyl-coenzyme A reductase activity|feruloyl coenzyme A reductase activity											RHEA:10620|EC:1.2.1.44|MetaCyc:CINNAMOYL-COA-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0019690	biolink:NamedThing	pyrimidine deoxyribonucleoside interconversion	The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside.	got7fsn_ti														biological_process											owl:Class	
GO:0019689	biolink:NamedThing	pyrimidine nucleoside interconversion	The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside.	got7fsn_ti														biological_process											owl:Class	
GO:0030043	biolink:NamedThing	actin filament fragmentation	The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0030042	biolink:NamedThing	actin filament depolymerization	Disassembly of actin filaments by the removal of actin monomers from a filament.	got7fsn_ti	actin depolymerizing activity|actin depolymerization													biological_process											owl:Class	
GO:0047785	biolink:NamedThing	cortisol sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H(+).	got7fsn_ti	glucocorticosteroid sulfotransferase activity|glucocorticoid sulfotransferase activity|3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase activity|cortisol sulphotransferase activity											KEGG_REACTION:R02839|MetaCyc:CORTISOL-SULFOTRANSFERASE-RXN|EC:2.8.2.18|RHEA:11884		molecular_function											owl:Class	
GO:0050256	biolink:NamedThing	ribitol-5-phosphate 2-dehydrogenase activity	Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+.	got7fsn_ti	dehydrogenase, ribitol 5-phosphate|D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase activity											MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN|EC:1.1.1.137		molecular_function											owl:Class	
GO:0033240	biolink:NamedThing	positive regulation of cellular amine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.	got7fsn_ti	positive regulation of amine metabolism													biological_process											owl:Class	
GO:0043049	biolink:NamedThing	otic placode formation	The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain.	got7fsn_ti														biological_process											owl:Class	
GO:0060032	biolink:NamedThing	notochord regression	The developmental process in which the stucture of the notochord is destroyed in an embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0018556	biolink:NamedThing	2,2',3-trihydroxybiphenyl dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).	got7fsn_ti												UM-BBD_enzymeID:e0032|EC:1.13.11.-		molecular_function											owl:Class	
GO:0070576	biolink:NamedThing	vitamin D 24-hydroxylase activity	Catalysis of the hydroxylation of C-24 of any form of vitamin D.	got7fsn_ti	ergocalciferol 24-hydroxylase activity|vitamin D3 24-hydroxylase activity|vitamin D2 24-hydroxylase activity|cholecalciferol 24-hydroxylase activity|calciferol 24-hydroxylase activity						mah	2009-04-21T02:20:52Z						molecular_function											owl:Class	
GO:0060985	biolink:NamedThing	epicardium-derived cardiac vascular smooth muscle cell fate commitment	The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.	got7fsn_ti							dph	2009-10-06T03:11:11Z						biological_process											owl:Class	
GO:0097129	biolink:NamedThing	cyclin D2-CDK4 complex	A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:53:15Z						cellular_component											owl:Class	
GO:0031130	biolink:NamedThing	creation of an inductive signal	The process in which one cell or group of cells sends a signal over a short range to another cell or group of cells of different ancestry and developmental potential, thereby effecting a developmental change in the latter.	got7fsn_ti														biological_process											owl:Class	
GO:0010731	biolink:NamedThing	protein glutathionylation	The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.	got7fsn_ti	protein amino acid glutathionylation													biological_process											owl:Class	
GO:0030060	biolink:NamedThing	L-malate dehydrogenase activity	Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.	got7fsn_ti	NAD-dependent malic dehydrogenase activity|NAD-dependent malate dehydrogenase activity|MDH|malic dehydrogenase activity|NAD-malic dehydrogenase activity|NAD-malate dehydrogenase activity|L-malate-NAD+ oxidoreductase activity|malic acid dehydrogenase activity|(S)-malate:NAD+ oxidoreductase activity|NAD-linked malate dehydrogenase activity|NAD-L-malate dehydrogenase activity|NAD-specific malate dehydrogenase activity|malate (NAD) dehydrogenase activity											MetaCyc:MALATE-DEH-RXN|RHEA:21432|EC:1.1.1.37|Reactome:R-HSA-70979|Reactome:R-HSA-71783|Reactome:R-HSA-198508		molecular_function											owl:Class	
GO:0140573	biolink:NamedThing	histone H3-containing nucleosome	A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures.	got7fsn_ti	histone H3 containing nucleosome	https://github.com/geneontology/go-ontology/issues/20585					pg	2021-01-04T16:22:43Z						cellular_component											owl:Class	
GO:0046214	biolink:NamedThing	enterobactin catabolic process	The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.	got7fsn_ti	enterobactin degradation|enterobactin catabolism|enterobactin breakdown													biological_process											owl:Class	
GO:0019614	biolink:NamedThing	catechol-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.	got7fsn_ti	catechol breakdown|catechol catabolic process|catechol degradation|catechol catabolism													biological_process											owl:Class	
GO:0047692	biolink:NamedThing	ATP deaminase activity	Catalysis of the reaction: ATP + H2O = ITP + NH3.	got7fsn_ti	adenosine triphosphate deaminase activity|ATP aminohydrolase activity											EC:3.5.4.18|RHEA:13037|MetaCyc:ATP-DEAMINASE-RXN		molecular_function											owl:Class	
GO:0033278	biolink:NamedThing	cell proliferation in midbrain	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.	got7fsn_ti	cell proliferation in mesencephalon|mesencepahalic cell proliferation													biological_process											owl:Class	
GO:0061383	biolink:NamedThing	trabecula morphogenesis	The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.	got7fsn_ti							dph	2010-12-02T08:51:45Z						biological_process											owl:Class	
GO:0072312	biolink:NamedThing	metanephric glomerular epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.	got7fsn_ti							mah	2010-04-09T06:54:15Z						biological_process											owl:Class	
GO:1990265	biolink:NamedThing	platelet-derived growth factor complex	A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD).	got7fsn_ti	PDGF complex|PDGF-AA dimer|PDGF-AB dimer|PDGF-BB dimer|PDGF-DD dimer|PDGF-CC dimer				An example of this is PDGFA in human (P04085) in PMID:20534510 (inferred from direct assay).		bhm	2014-01-09T16:09:11Z						cellular_component											owl:Class	
GO:0050597	biolink:NamedThing	taxane 10-beta-hydroxylase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+).	got7fsn_ti	5-alpha-taxadienol-10-beta-hydroxylase activity|taxane 10b-hydroxylase activity|taxane 10beta-hydroxylase activity|taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating)											KEGG_REACTION:R06309|EC:1.14.14.105|MetaCyc:1.14.13.76-RXN|RHEA:15241		molecular_function											owl:Class	
GO:0000718	biolink:NamedThing	nucleotide-excision repair, DNA damage removal	The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage.	got7fsn_ti														biological_process											owl:Class	
GO:0002361	biolink:NamedThing	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.	got7fsn_ti	CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T cell development|CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0051089	biolink:NamedThing	constitutive protein ectodomain proteolysis	The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands.	got7fsn_ti														biological_process											owl:Class	
GO:0006509	biolink:NamedThing	membrane protein ectodomain proteolysis	The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).	got7fsn_ti	receptor shedding|membrane protein solubilization|ectoderm shedding|ectodomain cleavage													biological_process											owl:Class	
GO:0050393	biolink:NamedThing	vinylacetyl-CoA delta-isomerase activity	Catalysis of the reaction: vinylacetyl-CoA = crotonoyl-CoA.	got7fsn_ti	vinylacetyl-CoA delta3-delta2-isomerase activity|vinylacetyl-CoA D-isomerase activity|delta3-cis-delta2-trans-enoyl-CoA isomerase|vinylacetyl coenzyme A isomerase activity|vinylacetyl coenzyme A delta-isomerase activity											MetaCyc:VINYLACETYL-COA-DELTA-ISOMERASE-RXN|EC:5.3.3.3|KEGG_REACTION:R03031|RHEA:10572		molecular_function											owl:Class	
GO:0008736	biolink:NamedThing	L-fucose isomerase activity	Catalysis of the reaction: L-fucose = L-fuculose.	got7fsn_ti	L-fucose ketol-isomerase activity|L-fucose aldose-ketose-isomerase activity											MetaCyc:FUCISOM-RXN|RHEA:17233|EC:5.3.1.25		molecular_function											owl:Class	
GO:0006972	biolink:NamedThing	hyperosmotic response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.	got7fsn_ti	HOG response|response to hypertonicity|hypertonic response													biological_process											owl:Class	
GO:0097085	biolink:NamedThing	interferon regulatory factor 3-interferon regulatory factor 5 complex	An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 5.	got7fsn_ti	IRF3:IRF5 complex						pr	2011-06-21T06:30:30Z						cellular_component											owl:Class	
GO:0051368	biolink:NamedThing	peptidyl-threonine octanoylation	The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.	got7fsn_ti												RESID:AA0386		biological_process											owl:Class	
GO:0008331	biolink:NamedThing	high voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.	got7fsn_ti	high voltage gated calcium channel activity|Q-type calcium channel|P-type calcium channel|high voltage-dependent calcium channel activity|N-type calcium channel|L-type calcium channel													molecular_function											owl:Class	
GO:0022002	biolink:NamedThing	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway	The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell.	got7fsn_ti	Wnt receptor signaling involved in downregulation of anterior neural cell fate of the neural plate|Wnt receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in down regulation of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in inhibition of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway|negative regulation of anterior neural cell fate commitment of the neural plate by Wnt-activated signaling pathway													biological_process											owl:Class	
GO:0022001	biolink:NamedThing	negative regulation of anterior neural cell fate commitment of the neural plate	Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate.	got7fsn_ti	down-regulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate of the neural plate|inhibition of anterior neural cell fate of the neural plate|posteriorization|caudalization of neural plate|downregulation of anterior neural cell fate of the neural plate|down regulation of anterior neural cell fate of the neural plate													biological_process											owl:Class	
GO:0043857	biolink:NamedThing	N-acetylornithine carbamoyltransferase activity	Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H(+) + phosphate.	got7fsn_ti	carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase activity|N-acetylornithine transcarbamylase activity|AOTC|carbamoyl-phosphate:2-N-acetyl-L-ornithine carbamoyltransferase activity|acetylornithine transcarbamylase activity											KEGG_REACTION:R07245|RHEA:18609|EC:2.1.3.9|MetaCyc:2.1.3.9-RXN		molecular_function											owl:Class	
GO:0009733	biolink:NamedThing	response to auxin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.	got7fsn_ti	response to auxin stimulus													biological_process											owl:Class	
GO:0006385	biolink:NamedThing	transcription elongation from RNA polymerase III promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III.	got7fsn_ti	RNA elongation from Pol III promoter|RNA polymerase III transcription elongation factor activity													biological_process											owl:Class	
GO:0006354	biolink:NamedThing	DNA-templated transcription, elongation	The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.	got7fsn_ti	RNA elongation|transcription elongation, DNA-dependent|DNA-dependent transcription, elongation|transcriptional elongation, DNA-dependent													biological_process											owl:Class	
GO:0140253	biolink:NamedThing	cell-cell fusion	A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium.	got7fsn_ti	cell fusion|cell cell fusion	https://github.com/geneontology/go-ontology/issues/15939					pg	2018-08-13T18:38:18Z						biological_process											owl:Class	
GO:0001996	biolink:NamedThing	positive regulation of heart rate by epinephrine-norepinephrine	The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction.	got7fsn_ti	increased chronotropy by epinephrine-norepinephrine|upregulation of heart contraction rate by epinephrine-norepinephrine|positive regulation of heart contraction rate by adrenaline-noradrenaline|positive regulation of cardiac contraction rate by epinephrine-norepinephrine|stimulation of heart contraction rate by epinephrine-norepinephrine|up regulation of heart contraction rate by epinephrine-norepinephrine|up-regulation of heart contraction rate by epinephrine-norepinephrine|activation of heart contraction rate by epinephrine-norepinephrine|positive regulation of heart contraction rate by epinephrine-norepinephrine|positive control of heart contraction rate by epinephrine-norepinephrine													biological_process											owl:Class	
GO:0061418	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.	got7fsn_ti							dph	2012-01-23T01:05:59Z						biological_process											owl:Class	
GO:0008810	biolink:NamedThing	cellulase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.	got7fsn_ti	beta-1,4-glucanase activity|1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity|avicelase activity|endo-1,4-beta-glucanase activity|endoglucanase activity|beta-1,4-endoglucan hydrolase activity|celludextrinase activity|9.5 cellulase activity|cellulase A 3|endoglucanase D|cellulosin AP|pancellase SS|carboxymethyl cellulase activity|endo-1,4-beta-D-glucanase activity|endo-1,4-beta-D-glucanohydrolase activity|alkali cellulase activity|celluase A											MetaCyc:RXN-2043|EC:3.2.1.4		molecular_function											owl:Class	
GO:0103059	biolink:NamedThing	UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol oxoanion + UDP-L-rhamnose <=> H+ + kaempferol-3-rhamnoside + UDP(3-).	got7fsn_ti												MetaCyc:RXN1F-474|RHEA:61164		molecular_function											owl:Class	
GO:0071105	biolink:NamedThing	response to interleukin-11	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.	got7fsn_ti	response to IL-11						mah	2009-11-09T12:52:51Z						biological_process											owl:Class	
GO:0046681	biolink:NamedThing	response to carbamate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase.	got7fsn_ti	carbamate resistance|carbamate susceptibility/resistance													biological_process											owl:Class	
GO:0009103	biolink:NamedThing	lipopolysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.	got7fsn_ti	lipopolysaccharide anabolism|lipopolysaccharide biosynthesis|lipopolysaccharide synthesis|LPS biosynthetic process|lipopolysaccharide formation											KEGG_PATHWAY:map00540		biological_process											owl:Class	
GO:0060745	biolink:NamedThing	mammary gland branching involved in pregnancy	The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.	got7fsn_ti							dph	2009-06-22T08:25:19Z						biological_process											owl:Class	
GO:0006180	biolink:NamedThing	deoxyguanosine salvage	Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0036154	biolink:NamedThing	diacylglycerol acyl-chain remodeling	Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains.	got7fsn_ti	diglyceride acyl-chain remodeling						bf	2012-03-14T02:53:14Z						biological_process											owl:Class	
GO:0046339	biolink:NamedThing	diacylglycerol metabolic process	The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.	got7fsn_ti	diacylglycerol metabolism|diglyceride metabolism													biological_process											owl:Class	
GO:0005838	biolink:NamedThing	proteasome regulatory particle	A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.	got7fsn_ti	PA700-dependent proteasome activator|modulator complex|19S regulatory particle|PA700 proteasome activator													cellular_component											owl:Class	
GO:0055046	biolink:NamedThing	microgametogenesis	The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure.	got7fsn_ti	pollen development from the microspore											Wikipedia:Microgametogenesis		biological_process											owl:Class	
GO:0150007	biolink:NamedThing	clathrin-dependent synaptic vesicle endocytosis	Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds.	got7fsn_ti							bc	2017-12-01T10:11:35Z						biological_process											owl:Class	
GO:0101002	biolink:NamedThing	ficolin-1-rich granule	Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1.  Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry.	got7fsn_ti	ficolin granule|ficolin-1 rich granule													cellular_component											owl:Class	
GO:0099542	biolink:NamedThing	trans-synaptic signaling by endocannabinoid	Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand.	got7fsn_ti														biological_process											owl:Class	
GO:0099541	biolink:NamedThing	trans-synaptic signaling by lipid	Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.	got7fsn_ti														biological_process											owl:Class	
GO:0035642	biolink:NamedThing	histone methyltransferase activity (H3-R17 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3.	got7fsn_ti	histone methylase activity (H3-R17 specific)|histone-arginine N-methyltransferase activity (H3-R17 specific)						bf	2011-01-19T10:41:43Z						molecular_function											owl:Class	
GO:0071685	biolink:NamedThing	NADH dehydrogenase complex (plastoquinone)	An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids.	got7fsn_ti							mah	2010-02-19T05:20:45Z						cellular_component											owl:Class	
GO:0030964	biolink:NamedThing	NADH dehydrogenase complex	An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.	got7fsn_ti	NADH dehydrogenase complex (ubiquinone)|NADH dehydrogenase complex (plastoquinone)|NADH:plastoquinone reductase complex|Complex I|plastid NADH dehydrogenase complex (plastoquinone)|NADH dehydrogenase complex (quinone)				Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (quinone) activity ; GO:0050136'.						GO:0031677|GO:0030025|GO:0045280|GO:0031678|GO:0031675|GO:0030966	Wikipedia:NADH_dehydrogenase		cellular_component											owl:Class	
GO:0140093	biolink:NamedThing	esBAF complex	An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C.	got7fsn_ti	embryonic stem cell-specific BAF complex|embryonic stem cell-specific SWI/SNF complex						pg	2017-09-05T09:23:51Z						cellular_component											owl:Class	
GO:0061121	biolink:NamedThing	regulation of positive chemotaxis to cAMP by DIF-2	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.	got7fsn_ti							dph	2010-05-17T08:16:21Z						biological_process											owl:Class	
GO:0021504	biolink:NamedThing	neural fold hinge point formation	The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.	got7fsn_ti	neural fold furrowing													biological_process											owl:Class	
GO:0034716	biolink:NamedThing	Gemin3-Gemin4-Gemin5 complex	A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly.	got7fsn_ti														cellular_component											owl:Class	
GO:0035238	biolink:NamedThing	vitamin A biosynthetic process	The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.	got7fsn_ti	vitamin A anabolism|vitamin A biosynthesis|vitamin A formation|vitamin A synthesis													biological_process											owl:Class	
GO:0018710	biolink:NamedThing	acetone carboxylase activity	Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate.	got7fsn_ti	acetone:carbon-dioxide ligase (AMP-forming)											MetaCyc:6.4.1.6-RXN|KEGG_REACTION:R05735|EC:6.4.1.6|RHEA:18385		molecular_function											owl:Class	
GO:0016885	biolink:NamedThing	ligase activity, forming carbon-carbon bonds	Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti												EC:6.4.-.-		molecular_function											owl:Class	
GO:0010052	biolink:NamedThing	guard cell differentiation	The process in which a guard mother cell acquires the specialized features of a guard cell.	got7fsn_ti	stomatal cell differentiation													biological_process											owl:Class	
GO:0034279	biolink:NamedThing	syn-pimara-7,15-diene synthase activity	Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate.	got7fsn_ti	9alpha-copalyl-diphosphate diphosphate-lyase (9beta-pimara-7,15-diene-forming) activity											RHEA:25560|EC:4.2.3.35|MetaCyc:RXN-4883|KEGG_REACTION:R09117		molecular_function											owl:Class	
GO:0003988	biolink:NamedThing	acetyl-CoA C-acyltransferase activity	Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.	got7fsn_ti	beta-ketoadipyl-CoA thiolase activity|acyl-CoA:acetyl-CoA C-acyltransferase activity|pro-3-ketoacyl-CoA thiolase activity|3-ketoacyl CoA thiolase activity|acetoacetyl-CoA beta-ketothiolase activity|beta-ketoacyl-CoA thiolase activity|beta-ketoadipyl coenzyme A thiolase activity|3-oxoacyl-CoA thiolase activity|ketoacyl-coenzyme A thiolase activity|3-ketoacyl thiolase activity|2-keto-acyl thiolase activity|2-methylacetoacetyl-CoA thiolase|beta-ketothiolase activity|KAT|acetyl-CoA acyltransferase activity|ketoacyl-CoA acyltransferase activity|3-oxoacyl-coenzyme A thiolase activity|beta-ketoacyl coenzyme A thiolase activity|thiolase I|6-oxoacyl-CoA thiolase activity|3-ketoacyl-CoA thiolase activity|3-ketoacyl coenzyme A thiolase activity|long-chain 3-oxoacyl-CoA thiolase activity|oxoacyl-coenzyme A thiolase activity|3-ketothiolase activity											Reactome:R-HSA-77271|MetaCyc:KETOACYLCOATHIOL-RXN|Reactome:R-HSA-77321|EC:2.3.1.16|Reactome:R-HSA-390250|Reactome:R-HSA-77329|RHEA:21564|UM-BBD_reactionID:r1051|Reactome:R-HSA-8874745|Reactome:R-HSA-77340|Reactome:R-HSA-77304|Reactome:R-HSA-77309		molecular_function											owl:Class	
GO:0072741	biolink:NamedThing	protein localization to cell division site	A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division.	got7fsn_ti	protein localisation to cell division site						mah	2012-08-16T11:51:48Z						biological_process											owl:Class	
GO:0000291	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, exonucleolytic	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail.	got7fsn_ti	exonucleolytic degradation of mRNA|mRNA degradation, exonucleolytic|mRNA breakdown, exonucleolytic|nuclear mRNA catabolic process, exonucleolytic													biological_process											owl:Class	
GO:0071607	biolink:NamedThing	macrophage inflammatory protein-1 gamma production	The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CCL9 production|chemokine (C-C motif) ligand 9 production|MIP-1g production						mah	2010-02-05T04:19:52Z						biological_process											owl:Class	
GO:0023051	biolink:NamedThing	regulation of signaling	Any process that modulates the frequency, rate or extent of a signaling process.	got7fsn_ti	regulation of signaling process|regulation of signalling process							2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0062116	biolink:NamedThing	phenyloplast	A chloroplast-derived plastid in which the solid form of phenol is stored.	got7fsn_ti							dph	2019-03-15T11:57:05Z						cellular_component											owl:Class	
GO:0010146	biolink:NamedThing	fructan biosynthetic process	The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.	got7fsn_ti	fructan synthesis|fructan formation|fructan anabolism|levan biosynthetic process|levan biosynthesis|fructan biosynthesis											MetaCyc:PWY-822		biological_process											owl:Class	
GO:0102083	biolink:NamedThing	7,8-dihydromonapterin aldolase activity	Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol.	got7fsn_ti												MetaCyc:RXN-10857		molecular_function											owl:Class	
GO:0060604	biolink:NamedThing	mammary gland duct cavitation	Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.	got7fsn_ti	milk duct cavitation						dph	2009-05-15T09:34:07Z						biological_process											owl:Class	
GO:0050391	biolink:NamedThing	valine dehydrogenase (NADP) activity	Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH.	got7fsn_ti	valine dehydrogenase (NADP+) activity|L-valine:NADP+ oxidoreductase (deaminating)|valine dehydrogenase (nicotinanide adenine dinucleotide phosphate)											RHEA:11156|MetaCyc:VALINE-DEHYDROGENASE-NADP+-RXN|EC:1.4.1.8		molecular_function											owl:Class	
GO:0042010	biolink:NamedThing	interleukin-15 receptor activity	Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-15R|IL-15 receptor activity													molecular_function											owl:Class	
GO:0016691	biolink:NamedThing	chloride peroxidase activity	Catalysis of the reaction: 2 R-H + 2 chloride + hydrogen peroxide = 2 R-Cl + 2 H2O.	got7fsn_ti	cofactor-free chloroperoxidase activity|vanadium chloroperoxidase activity|chloride:hydrogen-peroxide oxidoreductase|chloroperoxidase activity|flavin-heme chloroperoxidase activity|haem chloroperoxidase activity|flavin-haem chloroperoxidase activity|heme chloroperoxidase activity										GO:0016957|GO:0016955|GO:0016958|GO:0016956	MetaCyc:CHLORIDE-PEROXIDASE-RXN|EC:1.11.1.10		molecular_function											owl:Class	
GO:0036068	biolink:NamedThing	light-independent chlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light.	got7fsn_ti	light-independent chlorophyll biosynthesis|light-independent chlorophyll synthesis|light independent chlorophyll biosynthetic process|light-independent chlorophyll anabolism|light-independent chlorophyll formation						bf	2011-12-15T04:44:18Z						biological_process											owl:Class	
GO:0015995	biolink:NamedThing	chlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.	got7fsn_ti	chlorophyll biosynthesis|chlorophyll formation|chlorophyll anabolism|chlorophyll synthesis											MetaCyc:CHLOROPHYLL-SYN		biological_process											owl:Class	
GO:0046574	biolink:NamedThing	glycuronidase activity	Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid.	got7fsn_ti	glucuronyl hydrolase activity													molecular_function											owl:Class	
GO:0034891	biolink:NamedThing	endosulfan diol dehydrogenase activity	Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1388		molecular_function											owl:Class	
GO:0046164	biolink:NamedThing	alcohol catabolic process	The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.	got7fsn_ti	alcohol degradation|alcohol breakdown|alcohol catabolism													biological_process											owl:Class	
GO:0070772	biolink:NamedThing	PAS complex	A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.	got7fsn_ti	autophagy-specific phosphatidylinositol 3-kinase complex						mah	2009-06-30T11:13:32Z						cellular_component											owl:Class	
GO:0021707	biolink:NamedThing	cerebellar granule cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0009926	biolink:NamedThing	auxin polar transport	The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.	got7fsn_ti														biological_process											owl:Class	
GO:0047472	biolink:NamedThing	3-carboxy-cis,cis-muconate cycloisomerase activity	Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H(+).	got7fsn_ti	3-carboxymuconolactone hydrolase activity|CMLE activity|3-carboxymuconate lactonizing enzyme activity|beta-carboxymuconate lactonizing enzyme activity|3-carboxymuconate cycloisomerase type II activity	https://github.com/geneontology/go-ontology/issues/21794									GO:0018842	EC:5.5.1.2|MetaCyc:5.5.1.2-RXN|KEGG_REACTION:R03307|RHEA:23656|UM-BBD_reactionID:r0582		molecular_function											owl:Class	
GO:0071136	biolink:NamedThing	alpha7-beta1 integrin-laminin alpha-2 complex	A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2.	got7fsn_ti	ITGA7-ITGB1-LAMA2 complex						mah	2009-11-13T02:29:42Z						cellular_component											owl:Class	
GO:0102801	biolink:NamedThing	anthocyanin 5-O-glucoside-4'''-O-malonyltransferase activity	Catalysis of the reaction: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + coenzyme A.	got7fsn_ti												EC:2.3.1.214|MetaCyc:RXN-8139|RHEA:35515		molecular_function											owl:Class	
GO:2000344	biolink:NamedThing	positive regulation of acrosome reaction	Any process that activates or increases the frequency, rate or extent of the acrosome reaction.	got7fsn_ti							yaf	2011-02-01T12:02:18Z						biological_process											owl:Class	
GO:0036128	biolink:NamedThing	CatSper complex	A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits.	got7fsn_ti	CATSPER channel|CatSper channel complex						bf	2012-03-02T10:26:48Z						cellular_component											owl:Class	
GO:0005891	biolink:NamedThing	voltage-gated calcium channel complex	A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.	got7fsn_ti	voltage-sensitive calcium channel complex|voltage-dependent calcium channel complex|voltage gated calcium channel complex													cellular_component											owl:Class	
GO:0021863	biolink:NamedThing	forebrain neuroblast differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti	abventricular progenitor cell differentiation|intermediate progenitor cell differentiation|non-surface dividing progenitor cell differentiation													biological_process											owl:Class	
GO:0014016	biolink:NamedThing	neuroblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.	got7fsn_ti														biological_process											owl:Class	
GO:1904057	biolink:NamedThing	negative regulation of sensory perception of pain	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain.	got7fsn_ti	inhibition of nociception|inhibition of perception of physiological pain|down-regulation of perception of physiological pain|down-regulation of sensory perception of pain|down regulation of nociception|inhibition of sensory perception of pain|down regulation of sensory perception of pain|downregulation of perception of physiological pain|down regulation of perception of physiological pain|negative regulation of nociception|downregulation of nociception|downregulation of sensory perception of pain|down-regulation of nociception|negative regulation of perception of physiological pain						sl	2015-03-18T20:33:57Z						biological_process											owl:Class	
GO:0061527	biolink:NamedThing	dopamine secretion, neurotransmission	The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-21T15:43:15Z						biological_process											owl:Class	
GO:0033851	biolink:NamedThing	lavandulyl diphosphate synthase activity	Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate.	got7fsn_ti	dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (lavandulyl-diphosphate-forming) activity|FDS-5											KEGG_REACTION:R08950|RHEA:21676|MetaCyc:2.5.1.69-RXN|EC:2.5.1.69		molecular_function											owl:Class	
GO:0019826	biolink:NamedThing	oxygen sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).	got7fsn_ti														molecular_function											owl:Class	
GO:0016575	biolink:NamedThing	histone deacetylation	The modification of histones by removal of acetyl groups.	got7fsn_ti														biological_process											owl:Class	
GO:0002497	biolink:NamedThing	proteasomal proteolysis associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:0002496	biolink:NamedThing	proteolysis associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:0071749	biolink:NamedThing	polymeric IgA immunoglobulin complex	A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	polymeric IgA antibody|polymeric IgA1 antibody|pIgA1 antibody|pIgA antibody				Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a polymeric forms.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0016442	biolink:NamedThing	RISC complex	A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.	got7fsn_ti	miRNP complex|micro-ribonucleoprotein complex|RNA-induced silencing complex										GO:0035068	Wikipedia:RNA-induced_silencing_complex		cellular_component											owl:Class	
GO:0031332	biolink:NamedThing	RNAi effector complex	Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0019649	biolink:NamedThing	formaldehyde assimilation	The pathways in which formaldehyde is processed and used as a carbon source for the cell.	got7fsn_ti														biological_process											owl:Class	
GO:0102581	biolink:NamedThing	cyanidin 3-O-glucoside-p-coumaroyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 4-coumaryl-CoA + H+ <=> cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + coenzyme A.	got7fsn_ti												MetaCyc:RXN-15327		molecular_function											owl:Class	
GO:0005225	biolink:NamedThing	volume-sensitive anion channel activity	Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.	got7fsn_ti	volume-regulated channel											Reactome:R-HSA-8941543		molecular_function											owl:Class	
GO:0005253	biolink:NamedThing	anion channel activity	Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient.	got7fsn_ti	non-selective anion channel activity											Reactome:R-HSA-432036|Reactome:R-HSA-432034		molecular_function											owl:Class	
GO:0021513	biolink:NamedThing	spinal cord dorsal/ventral patterning	The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.	got7fsn_ti	spinal cord dorsal-ventral patterning|spinal cord dorsoventral patterning													biological_process											owl:Class	
GO:0046775	biolink:NamedThing	suppression by virus of host cytokine production	Any viral process that results in the inhibition of host cell cytokine production.	got7fsn_ti	negative regulation by virus of host cytokine production													biological_process											owl:Class	
GO:0044831	biolink:NamedThing	modulation by virus of host cytokine production	Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism.	got7fsn_ti							jl	2014-02-06T12:49:02Z						biological_process											owl:Class	
GO:0019985	biolink:NamedThing	translesion synthesis	The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.	got7fsn_ti	bypass DNA synthesis													biological_process											owl:Class	
GO:1900047	biolink:NamedThing	negative regulation of hemostasis	Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis.	got7fsn_ti	down-regulation of hemostasis|downregulation of hemostasis|down regulation of hemostasis|inhibition of hemostasis						jl	2012-01-19T03:23:42Z						biological_process											owl:Class	
GO:0047724	biolink:NamedThing	inosine nucleosidase activity	Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine.	got7fsn_ti	inosine ribohydrolase activity|inosine-guanosine nucleosidase activity|inosinase activity											EC:3.2.2.2|MetaCyc:INOSINE-NUCLEOSIDASE-RXN|RHEA:16657		molecular_function											owl:Class	
GO:0031022	biolink:NamedThing	nuclear migration along microfilament	The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins.	got7fsn_ti	nuclear migration, microfilament-mediated													biological_process											owl:Class	
GO:0009011	biolink:NamedThing	starch synthase activity	Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1).	got7fsn_ti	ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|ADP-glucose starch synthase activity|ADP-glucose--starch glucosyltransferase activity|ADPglucose-starch glucosyltransferase activity|ADPG-starch glucosyltransferase activity|ADP-glucose transglucosylase activity|starch synthetase activity|adenosine diphosphate glucose-starch glucosyltransferase activity|glycogen synthase activity|starch (bacterial glycogen) synthase activity|ADPglucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|ADPG starch synthetase activity|adenosine diphosphoglucose-starch glucosyltransferase activity											MetaCyc:GLYCOGENSYN-RXN|EC:2.4.1.21		molecular_function											owl:Class	
GO:0043816	biolink:NamedThing	phosphoserine-tRNA(Cys) ligase activity	Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).	got7fsn_ti	O-phosphoseryl-tRNA(Cys) synthetase activity|phosphoserine--tRNA(Cys) ligase activity|phosphoserine-tRNACys ligase activity|SepRS											EC:6.1.1.27|RHEA:25678		molecular_function											owl:Class	
GO:0033913	biolink:NamedThing	glucan endo-1,2-beta-glucosidase activity	Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans.	got7fsn_ti	endo-(1->2)-beta-D-glucanase activity|beta-D-1,2-glucanase activity|1,2-beta-D-glucan glucanohydrolase activity|endo-1,2-beta-glucanase activity											EC:3.2.1.71|MetaCyc:3.2.1.71-RXN		molecular_function											owl:Class	
GO:0050066	biolink:NamedThing	lysine 2,3-aminomutase activity	Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate.	got7fsn_ti	L-lysine 2,3-aminomutase activity											EC:5.4.3.2|KEGG_REACTION:R00461|RHEA:19177|MetaCyc:LYSINE-23-AMINOMUTASE-RXN		molecular_function											owl:Class	
GO:0071921	biolink:NamedThing	cohesin loading	The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA.	got7fsn_ti	cohesin association with chromatin|cohesin localisation to chromatin|cohesin localization to chromatin						mah	2010-09-28T11:07:26Z						biological_process											owl:Class	
GO:0071168	biolink:NamedThing	protein localization to chromatin	Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.	got7fsn_ti	protein localisation to chromatin						mah	2009-11-20T11:51:20Z						biological_process											owl:Class	
GO:0035053	biolink:NamedThing	dorsal vessel heart proper cell fate commitment	The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0018001	biolink:NamedThing	N-terminal peptidyl-valine acetylation	The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine.	got7fsn_ti												RESID:AA0054		biological_process											owl:Class	
GO:0097508	biolink:NamedThing	xanthine DNA N-glycosylase activity	DNA N-glycosylase activity acting on deaminated guanine (xanthine).	got7fsn_ti	xanthine-DNA glycosylase activity						pr	2013-09-26T16:03:10Z						molecular_function											owl:Class	
GO:0035996	biolink:NamedThing	rhabdomere microvillus	Thin cylindrical membrane-covered projection on the surface of a rhabdomere.	got7fsn_ti							bf	2011-09-01T02:18:30Z						cellular_component											owl:Class	
GO:0140397	biolink:NamedThing	versiconal hemiacetal acetate esterase activity	Catalyzes the reactions: versiconal hemiacetal acetate + H(2)O <=> versiconal + acetate, as well as versiconol acetate + H(2)O <=> versiconol + acetate.	got7fsn_ti							pg	2019-11-29T10:14:17Z				MetaCyc:RXN-9488|EC:3.1.1.94|MetaCyc:RXN-9493|RHEA:35715		molecular_function											owl:Class	
GO:0018321	biolink:NamedThing	protein glucuronylation	The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose.	got7fsn_ti	protein amino acid glucuronylation													biological_process											owl:Class	
GO:0050230	biolink:NamedThing	purine imidazole-ring cyclase activity	Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O.	got7fsn_ti	DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing)|DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing; DNA-adenine-forming)|DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming)											MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN|EC:4.3.2.4		molecular_function											owl:Class	
GO:0030614	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide.	got7fsn_ti	oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulphide as acceptor											EC:1.20.4.-		molecular_function											owl:Class	
GO:0030613	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors											EC:1.20.-.-		molecular_function											owl:Class	
GO:0072252	biolink:NamedThing	metanephric juxtaglomerulus cell development	The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure.	got7fsn_ti							mah	2010-03-19T03:55:31Z						biological_process											owl:Class	
GO:0072142	biolink:NamedThing	juxtaglomerulus cell development	The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.	got7fsn_ti							mah	2010-02-24T01:42:53Z						biological_process											owl:Class	
GO:0032622	biolink:NamedThing	interleukin-19 production	The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-19 biosynthetic process|IL-19 secretion|ZMDA1 secretion|interleukin-19 secretion|IL-19 production										GO:0042236|GO:0072617			biological_process											owl:Class	
GO:0032484	biolink:NamedThing	Ral protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state.	got7fsn_ti														biological_process											owl:Class	
GO:0060050	biolink:NamedThing	positive regulation of protein glycosylation	Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.	got7fsn_ti	positive regulation of protein amino acid glycosylation													biological_process											owl:Class	
GO:0071502	biolink:NamedThing	cellular response to temperature stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.	got7fsn_ti	cellular response to thermal stimulus						mah	2009-12-18T02:56:45Z						biological_process											owl:Class	
GO:0007436	biolink:NamedThing	larval salivary gland morphogenesis	The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0034064	biolink:NamedThing	Tor2-Mei2-Ste11 complex	A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast.	got7fsn_ti														cellular_component											owl:Class	
GO:0050208	biolink:NamedThing	polysialic-acid O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9.	got7fsn_ti	acetyl-CoA:polysialic-acid O-acetyltransferase activity											EC:2.3.1.136|MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN|RHEA:11604		molecular_function											owl:Class	
GO:0035903	biolink:NamedThing	cellular response to immobilization stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.	got7fsn_ti	cellular response to immobilisation stress|cellular response to restraint stress						bf	2011-06-22T09:47:44Z						biological_process											owl:Class	
GO:0106103	biolink:NamedThing	COPII vesicles tethering complex	A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP65 and GM130 protein in H. sapiens and by Bug1 and Grh1 proteins in S. cerevisiae.	got7fsn_ti	GRASP65-GM130 complex|Bug1-Grh1 complex						hjd	2018-02-15T23:36:12Z						cellular_component											owl:Class	
GO:0099023	biolink:NamedThing	vesicle tethering complex	Any protein complex that plays a role in vesicle tethering.	got7fsn_ti														cellular_component											owl:Class	
GO:0102237	biolink:NamedThing	ATP:farnesol kinase activity	Catalysis of the reaction: 2-trans,-6-trans-farnesol + ATP = 2-trans,-6-trans-farnesyl monophosphate + ADP + H+.	got7fsn_ti	ATP-dependent farnesol kinase activity	https://github.com/geneontology/go-ontology/issues/21619										RHEA:61656|MetaCyc:RXN-12304		molecular_function											owl:Class	
GO:0004730	biolink:NamedThing	pseudouridylate synthase activity	Catalysis of the reaction: D-ribose 5-phosphate + uracil = H(2)O + pseudouridine 5'-phosphate.	got7fsn_ti	uracil hydro-lyase (adding D-ribose 5-phosphate)|5-ribosyluracil 5-phosphate synthetase activity|pseudouridylate synthetase activity|uracil hydrolyase activity|pseudouridine-5'-phosphate glycosidase activity|psiUMP synthetase activity|pseudouridine monophosphate synthase activity|pseudouridylic acid synthetase activity|uracil hydro-lyase (adding D-ribose 5-phosphate; pseudouridine-5'-phosphate-forming)|pseudouridine monophosphate synthetase activity				Note that this term should not be confused with 'pseudouridine synthase activity ; GO:0009982', which refers to the intramolecular isomerization of uridine to pseudouridine.							RHEA:18337|KEGG_REACTION:R01055|EC:4.2.1.70|MetaCyc:PSEUDOURIDYLATE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0000048	biolink:NamedThing	peptidyltransferase activity	Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2).	got7fsn_ti	peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase activity											MetaCyc:PEPTIDYLTRANSFERASE-RXN|Reactome:R-HSA-156912|EC:2.3.2.12		molecular_function											owl:Class	
GO:0048179	biolink:NamedThing	activin receptor complex	A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed.	got7fsn_ti														cellular_component											owl:Class	
GO:0035910	biolink:NamedThing	ascending aorta morphogenesis	The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.	got7fsn_ti							bf	2011-06-24T11:14:52Z						biological_process											owl:Class	
GO:0051908	biolink:NamedThing	double-stranded DNA 5'-3' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule.	got7fsn_ti	double-stranded DNA specific 5'-3' exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0008309	biolink:NamedThing	double-stranded DNA exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule.	got7fsn_ti	double-stranded DNA specific exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0086064	biolink:NamedThing	cell communication by electrical coupling involved in cardiac conduction	The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction.	got7fsn_ti							dph	2011-11-22T08:49:44Z						biological_process											owl:Class	
GO:0039004	biolink:NamedThing	specification of pronephric proximal tubule identity	The process in which the proximal tubule of the pronephric nephron acquires its identity.	got7fsn_ti							bf	2010-07-02T09:30:30Z						biological_process											owl:Class	
GO:0072082	biolink:NamedThing	specification of proximal tubule identity	The process in which the proximal tubule of the kidney nephron acquires its identity.	got7fsn_ti							mah	2010-02-01T02:44:34Z						biological_process											owl:Class	
GO:1901479	biolink:NamedThing	benomyl transmembrane transporter activity	Enables the transfer of benomyl from one side of a membrane to the other.	got7fsn_ti	benomyl transporter activity						tb	2012-10-04T23:21:10Z			GO:0015242			molecular_function											owl:Class	
GO:0018029	biolink:NamedThing	peptidyl-lysine palmitoylation	The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine.	got7fsn_ti												RESID:AA0077		biological_process											owl:Class	
GO:0097584	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p.	got7fsn_ti	Pmt5p-Pmt2p complex						pr	2014-03-02T18:17:22Z						cellular_component											owl:Class	
GO:0031502	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase complex	A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.	got7fsn_ti	PMT family mannosyltransferase complex|protein O-mannosyltransferase complex				Note that GO:0004169 'dolichyl-phosphate-mannose-protein mannosyltransferase activity' (part of protein O-linked mannosylation) has never been observed in green plants. However, N- and C-mannosylation may occur in these species; see figure 1 in PMID:21558543.									cellular_component											owl:Class	
GO:0044170	biolink:NamedThing	host cell smooth endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host smooth ER has no ribosomes adhering to the outer surface.	got7fsn_ti	host smooth endoplasmic reticulum						jl	2009-09-04T11:33:29Z						cellular_component											owl:Class	
GO:0005521	biolink:NamedThing	lamin binding	Binding to lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.	got7fsn_ti	lamin/chromatin binding													molecular_function											owl:Class	
GO:0004345	biolink:NamedThing	glucose-6-phosphate dehydrogenase activity	Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.	got7fsn_ti	D-glucose 6-phosphate dehydrogenase activity|Entner-doudoroff enzyme|glucose 6-phosphate dehydrogenase (NADP) activity|6-phosphoglucose dehydrogenas|G6PD activity|GDH|glucose-6-phosphate 1-dehydrogenase activity|NADP-glucose-6-phosphate dehydrogenase activity|6-phosphoglucose dehydrogenase activity|zwischenferment|G6PDH|Zwischenferment|D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity|NADP-dependent glucose 6-phosphate dehydrogenase activity											RHEA:15841|MetaCyc:GLU6PDEHYDROG-RXN|EC:1.1.1.49|Reactome:R-HSA-70377		molecular_function											owl:Class	
GO:0048331	biolink:NamedThing	axial mesoderm structural organization	The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	axial mesoderm structural organisation													biological_process											owl:Class	
GO:0048338	biolink:NamedThing	mesoderm structural organization	The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	mesoderm structural organisation													biological_process											owl:Class	
GO:0052696	biolink:NamedThing	flavonoid glucuronidation	The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor.	got7fsn_ti	flavonoid glucuronoside biosynthetic process|flavonoid glucuronide biosynthetic process|flavonoid glucuronoside biosynthesis|flavonoid glucuronide biosynthesis						ai	2011-07-27T05:37:44Z						biological_process											owl:Class	
GO:0042379	biolink:NamedThing	chemokine receptor binding	Binding to a chemokine receptor.	got7fsn_ti	chemokine receptor ligand													molecular_function											owl:Class	
GO:0010076	biolink:NamedThing	maintenance of floral meristem identity	The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0019978	biolink:NamedThing	interleukin-3 binding	Binding to interleukin-3.	got7fsn_ti	IL-3 binding													molecular_function											owl:Class	
GO:0006596	biolink:NamedThing	polyamine biosynthetic process	The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.	got7fsn_ti	polyamine biosynthesis|polyamine anabolism|polyamine formation|polyamine synthesis											MetaCyc:POLYAMSYN-PWY		biological_process											owl:Class	
GO:0071371	biolink:NamedThing	cellular response to gonadotropin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.	got7fsn_ti	cellular response to gonadotrophin stimulus						mah	2009-12-11T03:14:35Z						biological_process											owl:Class	
GO:0052817	biolink:NamedThing	very long chain acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18.	got7fsn_ti	very long-chain acyl coenzyme A hydrolase activity|very long-chain hydrolase activity|very long-chain-acyl-CoA hydrolase activity|very long-chain acyl-thioester hydrolase activity						ai	2011-10-27T12:18:28Z						molecular_function											owl:Class	
GO:0052816	biolink:NamedThing	long-chain acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length.	got7fsn_ti	long-chain acyl-thioester hydrolase activity|long-chain hydrolase activity|long-chain acyl coenzyme A hydrolase activity|long-chain-acyl-CoA hydrolase activity						ai	2011-10-25T05:31:11Z						molecular_function											owl:Class	
GO:0044522	biolink:NamedThing	envenomation resulting in myocyte killing in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism.	got7fsn_ti	envenomation resulting in myocyte killing causing muscle damage in other organism						jl	2012-02-27T12:33:57Z						biological_process											owl:Class	
GO:0044521	biolink:NamedThing	envenomation resulting in muscle damage in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism.	got7fsn_ti							jl	2012-02-27T12:31:08Z						biological_process											owl:Class	
GO:0060938	biolink:NamedThing	epicardium-derived cardiac fibroblast cell differentiation	The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T01:28:03Z						biological_process											owl:Class	
GO:0060935	biolink:NamedThing	cardiac fibroblast cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T01:20:04Z						biological_process											owl:Class	
GO:1990135	biolink:NamedThing	flavonoid sulfotransferase activity	Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.	got7fsn_ti							tb	2013-06-28T22:07:27Z						molecular_function											owl:Class	
GO:0030876	biolink:NamedThing	interleukin-20 receptor complex	A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits.	got7fsn_ti	IL-20 receptor complex													cellular_component											owl:Class	
GO:0035214	biolink:NamedThing	eye-antennal disc development	Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.	got7fsn_ti														biological_process											owl:Class	
GO:0043675	biolink:NamedThing	sculpture element	The third layer of the sexine.	got7fsn_ti														cellular_component											owl:Class	
GO:0060054	biolink:NamedThing	positive regulation of epithelial cell proliferation involved in wound healing	Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.	got7fsn_ti														biological_process											owl:Class	
GO:0050679	biolink:NamedThing	positive regulation of epithelial cell proliferation	Any process that activates or increases the rate or extent of epithelial cell proliferation.	got7fsn_ti	upregulation of epithelial cell proliferation|activation of epithelial cell proliferation|up-regulation of epithelial cell proliferation|stimulation of epithelial cell proliferation|up regulation of epithelial cell proliferation													biological_process											owl:Class	
GO:0000791	biolink:NamedThing	euchromatin	A dispersed and relatively uncompacted form of chromatin.	got7fsn_ti	nuclear euchromatin										GO:0005719	NIF_Subcellular:sao445485807|Wikipedia:Euchromatin		cellular_component											owl:Class	
GO:0018410	biolink:NamedThing	C-terminal protein amino acid modification	The alteration of the C-terminal amino acid residue in a protein.	got7fsn_ti	peptide or protein carboxyl-terminal blocking|peptide/protein carboxyl-terminal blocking													biological_process											owl:Class	
GO:0043687	biolink:NamedThing	post-translational protein modification	The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.	got7fsn_ti	PTM|posttranslational amino acid modification|posttranslational protein modification|post-translational amino acid modification|posttranslational modification|post-translational modification				This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.							Wikipedia:Posttranslational_modification		biological_process											owl:Class	
GO:0008892	biolink:NamedThing	guanine deaminase activity	Catalysis of the reaction: guanine + H2O = xanthine + NH3.	got7fsn_ti	guanine aminohydrolase activity|guanine aminase activity|guanase activity|GAH activity											Reactome:R-HSA-74255|EC:3.5.4.3|RHEA:14665|MetaCyc:GUANINE-DEAMINASE-RXN		molecular_function											owl:Class	
GO:0052496	biolink:NamedThing	occlusion by host of symbiont xylem	The process in which an organism reduces the flow of fluid within the symbiont xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0052497	biolink:NamedThing	occlusion by organism of xylem in other organism involved in symbiotic interaction	The process in which an organism reduces the flow of fluid within the xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves, of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	occlusion by organism of xylem in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0004070	biolink:NamedThing	aspartate carbamoyltransferase activity	Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate.	got7fsn_ti	aspartic transcarbamylase activity|aspartic acid transcarbamoylase activity|carbamoylaspartotranskinase activity|L-aspartate transcarbamoylase activity|aspartate transcarbamoylase activity|aspartic carbamyltransferase activity|carbamoyl-phosphate:L-aspartate carbamoyltransferase activity|aspartate transcarbamylase activity|L-aspartate transcarbamylase activity|aspartate carbamyltransferase activity|ATCase activity|carbamylaspartotranskinase activity											MetaCyc:ASPCARBTRANS-RXN|RHEA:20013|EC:2.1.3.2|KEGG_REACTION:R01397|Reactome:R-HSA-73573		molecular_function											owl:Class	
GO:0075330	biolink:NamedThing	positive regulation of arbuscule formation for nutrient acquisition from host	Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0075329	biolink:NamedThing	regulation of arbuscule formation for nutrient acquisition from host	Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0071099	biolink:NamedThing	alphaV-beta6 integrin-TGFbeta-3 complex	A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).	got7fsn_ti	ITGAV-ITGB6-TFGB3 complex						mah	2009-11-06T04:52:27Z						cellular_component											owl:Class	
GO:0043774	biolink:NamedThing	coenzyme F420-2 alpha-glutamyl ligase activity	Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate.	got7fsn_ti	F420-2 alpha-glutamyl ligase activity											EC:6.3.2.32|RHEA:42332		molecular_function											owl:Class	
GO:0061967	biolink:NamedThing	establishment of left sidedness	The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side.	got7fsn_ti							dph	2018-02-12T16:32:41Z						biological_process											owl:Class	
GO:0061966	biolink:NamedThing	establishment of left/right asymmetry	The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.	got7fsn_ti							dph	2018-02-12T16:27:20Z						biological_process											owl:Class	
GO:0051700	biolink:NamedThing	fructosyl-amino acid oxidase activity	Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2.	got7fsn_ti	FAOD activity													molecular_function											owl:Class	
GO:0072114	biolink:NamedThing	pronephros morphogenesis	The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	got7fsn_ti	pronephric kidney morphogenesis						mah	2010-02-22T11:12:15Z						biological_process											owl:Class	
GO:0006639	biolink:NamedThing	acylglycerol metabolic process	The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.	got7fsn_ti	acylglycerol metabolism|glyceride metabolism|glyceride metabolic process													biological_process											owl:Class	
GO:0039668	biolink:NamedThing	viral entry into host cell via pilus basal pore	The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way.	got7fsn_ti	filamentous viral entry into host cell via pilus retraction						bf	2013-09-04T14:33:18Z						biological_process											owl:Class	
GO:0039667	biolink:NamedThing	viral entry into host cell via pilus retraction	The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus.	got7fsn_ti					This method of entry into the cell differs between viruses; filamentous bacteriophages have rod-shaped virions which attach to the tip of the pilus; after retraction of the pilus with the virion attached, the genome can enter the host cell through the pilus basal pore. For icosahedral viruses, retraction of the pilus brings the virus in contact with the cell membrane and the genome can enter the cell via membrane fusion or genome injection. In GO, viral entry begins after viral attachment; for pilus-attachment proteins see instead: viral attachment to host cell pilus ; GO:0039666.		bf	2013-09-04T14:32:19Z						biological_process											owl:Class	
GO:0033843	biolink:NamedThing	xyloglucan 6-xylosyltransferase activity	Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage.	got7fsn_ti	uridine diphosphoxylose-xyloglucan 6alpha-xylosyltransferase activity|xyloglucan 6-alpha-D-xylosyltransferase activity|UDP-D-xylose:xyloglucan 1,6-alpha-D-xylosyltransferase activity											EC:2.4.2.39|MetaCyc:2.4.2.39-RXN		molecular_function											owl:Class	
GO:1990438	biolink:NamedThing	U6 2'-O-snRNA methylation	The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule.	got7fsn_ti							mah	2014-07-31T12:04:21Z						biological_process											owl:Class	
GO:1990437	biolink:NamedThing	snRNA 2'-O-methylation	The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule.	got7fsn_ti							mah	2014-07-31T11:58:18Z						biological_process											owl:Class	
GO:0033528	biolink:NamedThing	S-methylmethionine cycle	A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.	got7fsn_ti												MetaCyc:PWY-5441		biological_process											owl:Class	
GO:0033477	biolink:NamedThing	S-methylmethionine metabolic process	The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.	got7fsn_ti	S-methylmethionine metabolism													biological_process											owl:Class	
GO:0009270	biolink:NamedThing	response to humidity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.	got7fsn_ti														biological_process											owl:Class	
GO:0008420	biolink:NamedThing	RNA polymerase II CTD heptapeptide repeat phosphatase activity	Catalysis of the reaction: phospho-(DNA-directed RNA polymerase II) + H2O = (DNA-directed RNA polymerase II) + phosphate.	got7fsn_ti	CTD phosphatase activity|RNA polymerase II carboxy-terminal domain phosphatase activity													molecular_function											owl:Class	
GO:0001570	biolink:NamedThing	vasculogenesis	The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.	got7fsn_ti	vascular morphogenesis											Wikipedia:Vasculogenesis		biological_process											owl:Class	
GO:0006465	biolink:NamedThing	signal peptide processing	The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.	got7fsn_ti	leader peptide processing													biological_process											owl:Class	
GO:0044291	biolink:NamedThing	cell-cell contact zone	Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.	got7fsn_ti	cell cell contact zone						jl	2010-02-04T02:42:54Z				NIF_Subcellular:sao1299635018		cellular_component											owl:Class	
GO:0005911	biolink:NamedThing	cell-cell junction	A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects.	got7fsn_ti	intercellular junction											NIF_Subcellular:sao1922892319		cellular_component											owl:Class	
GO:0050797	biolink:NamedThing	thymidylate synthase (FAD) activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.	got7fsn_ti	FDTS activity|ThyX activity|Thy1 activity|5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity|flavin dependent thymidylate synthase activity											MetaCyc:RXN-8850|RHEA:29043|EC:2.1.1.148|KEGG_REACTION:R06613		molecular_function											owl:Class	
GO:0042083	biolink:NamedThing	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.	got7fsn_ti														molecular_function											owl:Class	
GO:0018969	biolink:NamedThing	thiocyanate metabolic process	The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.	got7fsn_ti	thiocyanic acid metabolic process|thiocyanate metabolism|thiocyanic acid metabolism											UM-BBD_pathwayID:thc|MetaCyc:P581-PWY		biological_process											owl:Class	
GO:0052613	biolink:NamedThing	canthaxanthin 3-hydroxylase activity	Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O.	got7fsn_ti	carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity											MetaCyc:RXN-8186		molecular_function											owl:Class	
GO:0060051	biolink:NamedThing	negative regulation of protein glycosylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.	got7fsn_ti	negative regulation of protein amino acid glycosylation													biological_process											owl:Class	
GO:1901277	biolink:NamedThing	tartrate biosynthetic process	The chemical reactions and pathways resulting in the formation of tartrate.	got7fsn_ti	tartrate biosynthesis|tartrate anabolism|tartrate synthesis|tartrate formation						yaf	2012-08-17T14:52:48Z						biological_process											owl:Class	
GO:0021931	biolink:NamedThing	rostral hindbrain neuronal precursor cell proliferation	The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus.	got7fsn_ti														biological_process											owl:Class	
GO:0021924	biolink:NamedThing	cell proliferation in external granule layer	The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere.	got7fsn_ti														biological_process											owl:Class	
GO:0006777	biolink:NamedThing	Mo-molybdopterin cofactor biosynthetic process	The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.	got7fsn_ti	molybdenum cofactor biosynthetic process|Mo-molybdopterin cofactor biosynthesis|Moco biosynthesis|Mo-molybdopterin cofactor anabolism|Moco biosynthetic process|Mo-molybdopterin cofactor synthesis|Mo-molybdopterin cofactor formation											MetaCyc:PWY-6823		biological_process											owl:Class	
GO:1990252	biolink:NamedThing	Syp1 complex	A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis.	got7fsn_ti	Syp1 dimer						bhm	2013-12-09T14:43:00Z						cellular_component											owl:Class	
GO:0007117	biolink:NamedThing	budding cell bud growth	The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.	got7fsn_ti	bud growth													biological_process											owl:Class	
GO:2000260	biolink:NamedThing	regulation of blood coagulation, common pathway	Any process that modulates the frequency, rate or extent of blood coagulation, common pathway.	got7fsn_ti							mah	2010-11-23T11:42:40Z						biological_process											owl:Class	
GO:0007596	biolink:NamedThing	blood coagulation	The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.	got7fsn_ti	blood clotting											Wikipedia:Coagulation		biological_process											owl:Class	
GO:0098910	biolink:NamedThing	regulation of atrial cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti							tb	2011-11-10T08:49:13Z						biological_process											owl:Class	
GO:0072173	biolink:NamedThing	metanephric tubule morphogenesis	The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.	got7fsn_ti							mah	2010-02-26T02:06:42Z						biological_process											owl:Class	
GO:0072170	biolink:NamedThing	metanephric tubule development	The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.	got7fsn_ti							mah	2010-02-26T01:58:18Z						biological_process											owl:Class	
GO:1990331	biolink:NamedThing	Hpa2 acetyltransferase complex	A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules.	got7fsn_ti							bhm	2014-03-17T10:18:23Z						cellular_component											owl:Class	
GO:0060271	biolink:NamedThing	cilium assembly	The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.	got7fsn_ti	cilium biogenesis|cilium formation|microtubule-based flagellum assembly|ciliogenesis|cilium organization|cilium assembly|cilium morphogenesis				Note that we deem cilium and microtubule-based flagellum to be equivalent.						GO:0042384	Reactome:R-HSA-5617833.2		biological_process											owl:Class	
NCBITaxon:2759	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000551	biolink:NamedThing	regulation of T-helper 2 cell cytokine production	Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production.	got7fsn_ti	regulation of Th2 cell cytokine production						ebc	2011-04-03T07:32:47Z						biological_process											owl:Class	
GO:0004913	biolink:NamedThing	interleukin-4 receptor activity	Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-4 receptor activity|IL-4R													molecular_function											owl:Class	
GO:0021822	biolink:NamedThing	negative regulation of cell motility involved in cerebral cortex radial glia guided migration	The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.	got7fsn_ti	negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration|inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration|down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration													biological_process											owl:Class	
GO:0008347	biolink:NamedThing	glial cell migration	The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.	got7fsn_ti	glia cell migration										GO:0043359			biological_process											owl:Class	
GO:0001072	biolink:NamedThing	transcription antitermination factor activity, RNA binding	Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein.	got7fsn_ti	RNA binding transcription antitermination factor activity						krc	2010-10-21T04:48:17Z						molecular_function											owl:Class	
GO:0031564	biolink:NamedThing	transcription antitermination	Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s).	got7fsn_ti	transcriptional readthrough													biological_process											owl:Class	
GO:0021801	biolink:NamedThing	cerebral cortex radial glia-guided migration	The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex.	got7fsn_ti	glial-guided locomotion|cerebral cortex radial glia guided migration|cerebral cortex radial glia-dependent cell migration													biological_process											owl:Class	
CL:0000125	biolink:NamedThing			got7fsn_ti																									owl:Class	
NCBITaxon:2	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097278	biolink:NamedThing	complement-dependent cytotoxicity	Cell killing caused by the membrane attack complex formed following complement activation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18715					pr	2012-03-22T05:04:04Z						biological_process											owl:Class	
GO:0006956	biolink:NamedThing	complement activation	Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.	got7fsn_ti	complement response|complement cascade|complement activity													biological_process											owl:Class	
GO:0044543	biolink:NamedThing	envenomation resulting in zymogen activation in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the proteolytic processing of an inactive enzyme to an active form.	got7fsn_ti							jl	2012-03-22T11:52:56Z						biological_process											owl:Class	
GO:0048612	biolink:NamedThing	post-embryonic ectodermal digestive tract development	The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.	got7fsn_ti	post-embryonic ectodermal gut development													biological_process											owl:Class	
GO:0030672	biolink:NamedThing	synaptic vesicle membrane	The lipid bilayer surrounding a synaptic vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0043673	biolink:NamedThing	sexine	The outer, sculptured layer of the exine, which lies above the nexine.	got7fsn_ti					Note that the sexine sometimes consists of 5 layers, but of those, 3 layers are the most common (sexine 1 = columellae; sexine 2 = tectum; sexine 3 = sculpture elements). Sexine is distinguished on purely morphological criteria; compare with 'ectexine ; GO:0043669'. See also 'nexine ; GO:0043672'.									cellular_component											owl:Class	
GO:0043668	biolink:NamedThing	exine	The outer layer of the pollen grain wall which is composed primarily of sporopollenin.	got7fsn_ti					Note that the exine is highly resistant to strong acids and bases.									cellular_component											owl:Class	
GO:0048919	biolink:NamedThing	posterior lateral line neuromast development	The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.	got7fsn_ti														biological_process											owl:Class	
GO:0005756	biolink:NamedThing	mitochondrial proton-transporting ATP synthase, central stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis.	got7fsn_ti														cellular_component											owl:Class	
GO:0000275	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)	The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.	got7fsn_ti	proton-transporting ATP synthase complex, catalytic core F(1)|hydrogen-transporting ATP synthase, F1 sector				See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.									cellular_component											owl:Class	
GO:0090104	biolink:NamedThing	pancreatic epsilon cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin.	got7fsn_ti	pancreatic E cell differentiation						tb	2009-11-18T11:48:52Z						biological_process											owl:Class	
GO:0031018	biolink:NamedThing	endocrine pancreas development	The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.	got7fsn_ti														biological_process											owl:Class	
GO:0003164	biolink:NamedThing	His-Purkinje system development	The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.	got7fsn_ti							dph	2009-10-01T02:07:12Z						biological_process											owl:Class	
GO:0003161	biolink:NamedThing	cardiac conduction system development	The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.	got7fsn_ti	heart conduction system development|cardiac impulse conducting system development						dph	2009-10-01T01:57:16Z						biological_process											owl:Class	
GO:0036071	biolink:NamedThing	N-glycan fucosylation	The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains.	got7fsn_ti	glycoprotein fucosylation						bf	2011-12-15T04:54:24Z						biological_process											owl:Class	
GO:0031633	biolink:NamedThing	xanthophore	A chromatophore containing yellow pigment.	got7fsn_ti					Note that this term refers to a subcellular structure, and should not be confused with the specialized cells known as xanthophores, which produce yellow pigment and are found in fish and amphibian skin. Note that several terms in the biological process ontology ('xanthophore differentiation ; GO:0050936' and its children) refer to xanthophores in the sense of pigment-producing cells.									cellular_component											owl:Class	
NCBITaxon:Union_0000004	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002802	biolink:NamedThing	positive regulation of antifungal peptide secretion	Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion.	got7fsn_ti	upregulation of antifungal peptide secretion|activation of antifungal peptide secretion|up-regulation of antifungal peptide secretion|stimulation of antifungal peptide secretion|up regulation of antifungal peptide secretion													biological_process											owl:Class	
GO:0002781	biolink:NamedThing	antifungal peptide production	The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
NCBITaxon:2864	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0080001	biolink:NamedThing	mucilage extrusion from seed coat	The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat.	got7fsn_ti	secretion of mucilage from seed coat|mucilage release from seed coat													biological_process											owl:Class	
GO:1990180	biolink:NamedThing	mitochondrial tRNA 3'-end processing	The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.	got7fsn_ti	tRNA 3'-end processing in mitochondria|tRNA 3' processing in mitochondrion|tRNA 3' processing in mitochondria						mah	2013-08-30T16:17:36Z						biological_process											owl:Class	
GO:0033290	biolink:NamedThing	eukaryotic 48S preinitiation complex	A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA.	got7fsn_ti	eukaryotic 48S initiation complex|eukaryotic 48S pre-initiation complex										GO:0016283			cellular_component											owl:Class	
GO:0022627	biolink:NamedThing	cytosolic small ribosomal subunit	The small subunit of a ribosome located in the cytosol.	got7fsn_ti	prokaryotic small ribosomal subunit|40S ribosomal subunit|eukaryotic ribosomal SSU|30S ribosomal subunit										GO:0009283|GO:0030499|GO:0030873|GO:0005843			cellular_component											owl:Class	
GO:0015095	biolink:NamedThing	magnesium ion transmembrane transporter activity	Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-5336454|Reactome:R-HSA-5339538|Reactome:R-HSA-5336466|RHEA:29827|Reactome:R-HSA-5339528|Reactome:R-HSA-442661|Reactome:R-HSA-5336453		molecular_function											owl:Class	
GO:1903830	biolink:NamedThing	magnesium ion transmembrane transport	The directed movement of magnesium ion across a membrane.	got7fsn_ti							mcc	2015-01-21T17:38:30Z						biological_process											owl:Class	
GO:1905080	biolink:NamedThing	negative regulation of cerebellar neuron development	Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.	got7fsn_ti	downregulation of cerebellar neuron development|inhibition of cerebellar neuron development|down-regulation of cerebellar neuron development|down regulation of cerebellar neuron development						hjd	2016-03-24T19:45:26Z						biological_process											owl:Class	
GO:0005816	biolink:NamedThing	spindle pole body	The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.	got7fsn_ti	SPB											Wikipedia:Spindle_pole_body		cellular_component											owl:Class	
GO:0005604	biolink:NamedThing	basement membrane	A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.	got7fsn_ti	basal lamina|basement lamina|lamina densa				Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer.						GO:0005605|GO:0008003	Wikipedia:Basement_membrane		cellular_component											owl:Class	
GO:0000354	biolink:NamedThing	cis assembly of pre-catalytic spliceosome	Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.	got7fsn_ti	spliceosomal A2-1 complex biosynthesis|spliceosomal A2-1 complex formation|cis assembly of U2-type pre-catalytic spliceosome|formation of spliceosomal B1 complex|cis assembly of U12-type pre-catalytic spliceosome|formation of spliceosomal A2-1 complex|spliceosomal B1 complex biosynthesis|spliceosomal B1 complex formation				Note that this step represents formation of the A2-1 complex (yeast) or the B1 complex (mammals).						GO:0000360|GO:0000361			biological_process											owl:Class	
GO:0000245	biolink:NamedThing	spliceosomal complex assembly	The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.	got7fsn_ti	spliceosome assembly													biological_process											owl:Class	
GO:0001844	biolink:NamedThing	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway.	got7fsn_ti	protein insertion into mitochondrial membrane involved in induction of apoptosis|protein insertion into mitochondrial membrane during induction of apoptosis|protein insertion into mitochondrion membrane during induction of apoptosis|insertion of proteins into mitochondrial membranes during the induction of apoptosis				Note that this term is intended to cover the insertion of pro-apoptotic proteins such as Bax or its homologs into mitochondrial membranes which occurs as an early step in the apoptotic program.									biological_process											owl:Class	
GO:0070931	biolink:NamedThing	Golgi-associated vesicle lumen	The volume enclosed by the membrane of a Golgi-associated vesicle.	got7fsn_ti							mah	2009-09-16T04:26:50Z						cellular_component											owl:Class	
NCBITaxon:4751	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042628	biolink:NamedThing	mating plug formation	The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males.	got7fsn_ti	copulatory plug formation|mating plug deposition|copulatory plug deposition|copulatory plug biosynthesis													biological_process											owl:Class	
GO:0007320	biolink:NamedThing	insemination	The introduction of semen or sperm into the genital tract of a female.	got7fsn_ti												Wikipedia:Insemination		biological_process											owl:Class	
GO:0048586	biolink:NamedThing	regulation of long-day photoperiodism, flowering	Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	got7fsn_ti														biological_process											owl:Class	
NCBITaxon:3398	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010019	biolink:NamedThing	chloroplast-nucleus signaling pathway	The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.	got7fsn_ti	chloroplast-nucleus signalling pathway													biological_process											owl:Class	
NCBITaxon:33090	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015627	biolink:NamedThing	type II protein secretion system complex	A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.	got7fsn_ti	T2SS-associated complexes|general secretion pathway-associated complex|main terminal branch|Sec-dependent secretion system-associated complex|MTB				Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'.									cellular_component											owl:Class	
GO:1990779	biolink:NamedThing	glycoprotein Ib-IX-V complex	A transmembrane signalling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation.	got7fsn_ti	GPIb-IX-V complex|CD42|GPIb-V-IX complex				An example of this is GB1BA in human (P07359) in PMID:1730602 (inferred from direct assay).		bhm	2015-06-23T11:22:12Z						cellular_component											owl:Class	
NCBITaxon:33208	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035047	biolink:NamedThing	centrosomal and pronuclear rotation	The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0007338	biolink:NamedThing	single fertilization	The union of male and female gametes to form a zygote.	got7fsn_ti	zygote formation|zygote biosynthesis													biological_process											owl:Class	
GO:0015134	biolink:NamedThing	hexuronate transmembrane transporter activity	Enables the transfer of hexuronates from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.	got7fsn_ti	hexuronide transmembrane transporter activity										GO:0015163			molecular_function											owl:Class	
GO:0090093	biolink:NamedThing	regulation of fungal-type cell wall beta-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.	got7fsn_ti							tb	2009-11-13T10:10:38Z						biological_process											owl:Class	
GO:0060395	biolink:NamedThing	SMAD protein signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.	got7fsn_ti														biological_process											owl:Class	
GO:0072120	biolink:NamedThing	pronephros maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	got7fsn_ti	pronephric kidney maturation						mah	2010-02-22T11:25:48Z						biological_process											owl:Class	
GO:0048793	biolink:NamedThing	pronephros development	The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	got7fsn_ti	pronephric kidney development													biological_process											owl:Class	
GO:0051298	biolink:NamedThing	centrosome duplication	The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	got7fsn_ti	centrosome replication													biological_process											owl:Class	
GO:0000399	biolink:NamedThing	cellular bud neck septin structure	Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle.	got7fsn_ti														cellular_component											owl:Class	
GO:0005935	biolink:NamedThing	cellular bud neck	The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.	got7fsn_ti														cellular_component											owl:Class	
GO:0097597	biolink:NamedThing	ventral disc	Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence.	got7fsn_ti	ventral adhesive disc|ventral disk|adhesive disc				Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:29:58Z						cellular_component											owl:Class	
GO:0031391	biolink:NamedThing	Elg1 RFC-like complex	A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.	got7fsn_ti	RFC (Elg1)|Elg1-RLC|Elg1-RFC													cellular_component											owl:Class	
GO:0005890	biolink:NamedThing	sodium:potassium-exchanging ATPase complex	Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior.	got7fsn_ti	sodium pump|sodium/potassium-exchanging ATPase complex													cellular_component											owl:Class	
GO:0080112	biolink:NamedThing	seed growth	The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo.	got7fsn_ti							dhl	2009-04-27T02:52:07Z						biological_process											owl:Class	
GO:0097592	biolink:NamedThing	ventral disc overlap zone	A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself).	got7fsn_ti	ventral disk overlap zone|overlap zone				Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:12:50Z						cellular_component											owl:Class	
GO:1905756	biolink:NamedThing	regulation of primary cell septum biogenesis	Any process that modulates the frequency, rate or extent of primary cell septum biogenesis.	got7fsn_ti							vw	2016-12-12T18:09:50Z						biological_process											owl:Class	
GO:0060298	biolink:NamedThing	positive regulation of sarcomere organization	Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	got7fsn_ti	positive regulation of sarcomere organisation													biological_process											owl:Class	
GO:0007293	biolink:NamedThing	germarium-derived egg chamber formation	Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
NCBITaxon:6656	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000071	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070558	biolink:NamedThing	alphaM-beta2 integrin-CD63 complex	A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.	got7fsn_ti	ITGAM-ITGB2-CD63 complex													cellular_component											owl:Class	
GO:0036214	biolink:NamedThing	contractile ring localization	The process in which a contractile ring is assembled and/or maintained in a specific location.	got7fsn_ti					This term can be used to annotate localization of either bacterial or fungal contractile rings.		bf	2012-04-26T02:58:50Z						biological_process											owl:Class	
GO:0061640	biolink:NamedThing	cytoskeleton-dependent cytokinesis	A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.	got7fsn_ti							dph	2014-08-22T14:21:35Z						biological_process											owl:Class	
GO:0009656	biolink:NamedThing	PSII associated light-harvesting complex II, peripheral complex	Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light.	got7fsn_ti														cellular_component											owl:Class	
GO:0009507	biolink:NamedThing	chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.	got7fsn_ti												Wikipedia:Chloroplast		cellular_component											owl:Class	
GO:0007188	biolink:NamedThing	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP).	got7fsn_ti	G protein signaling, coupled to cAMP nucleotide second messenger|G protein signaling, coupled to cyclic AMP nucleotide second messenger|G-protein signaling, coupled to cyclic AMP nucleotide second messenger|GPCR signaling pathway via cAMP second messenger|G protein signalling, coupled to cAMP nucleotide second messenger|G-protein signaling, coupled to cAMP nucleotide second messenger|GPCR signaling pathway via modulation of adenylate cyclase activity|G-protein signalling, coupled to cAMP nucleotide second messenger|adenylate cyclase-modulating GPCR signaling pathway|G-protein signalling, coupled to cyclic AMP nucleotide second messenger|G protein signalling, coupled to cyclic AMP nucleotide second messenger				This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase activity. For steps upstream of adenylate cyclase activity, consider instead annotating to 'regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway ; GO:0010578.									biological_process											owl:Class	
GO:0045761	biolink:NamedThing	regulation of adenylate cyclase activity	Any process that modulates the frequency, rate or extent of adenylate cyclase activity.	got7fsn_ti	adenylate cyclase regulator|regulation of adenylyl cyclase activity													biological_process											owl:Class	
GO:2001234	biolink:NamedThing	negative regulation of apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.	got7fsn_ti	negative regulation of apoptotic signalling pathway						pr	2011-11-24T01:20:54Z						biological_process											owl:Class	
GO:0070118	biolink:NamedThing	organellar chromatophore thylakoid membrane	The lipid bilayer membrane of any thylakoid within an organellar chromatophore.	got7fsn_ti	Paulinella-type chromatophore thylakoid membrane													cellular_component											owl:Class	
GO:0070116	biolink:NamedThing	organellar chromatophore thylakoid	A thylakoid located in an organellar chromatophore.	got7fsn_ti	Paulinella-type chromatophore thylakoid													cellular_component											owl:Class	
GO:0015168	biolink:NamedThing	glycerol transmembrane transporter activity	Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	got7fsn_ti														molecular_function											owl:Class	
GO:0015793	biolink:NamedThing	glycerol transport	The directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	got7fsn_ti														biological_process											owl:Class	
GO:0072282	biolink:NamedThing	metanephric nephron tubule morphogenesis	The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.	got7fsn_ti							mah	2010-04-01T03:25:11Z						biological_process											owl:Class	
GO:0048557	biolink:NamedThing	embryonic digestive tract morphogenesis	The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.	got7fsn_ti	embryonic gut morphogenesis										GO:0048558			biological_process											owl:Class	
GO:1904348	biolink:NamedThing	negative regulation of small intestine smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.	got7fsn_ti	down-regulation of small intestine smooth muscle contraction|inhibition of small intestine smooth muscle contraction|downregulation of small intestine smooth muscle contraction|down regulation of small intestine smooth muscle contraction						sl	2015-06-11T21:37:40Z						biological_process											owl:Class	
GO:0014831	biolink:NamedThing	gastro-intestinal system smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract).	got7fsn_ti														biological_process											owl:Class	
GO:1901251	biolink:NamedThing	positive regulation of lung goblet cell differentiation	Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation.	got7fsn_ti	positive regulation of pulmonary goblet cell differentiation|upregulation of lung goblet cell differentiation|upregulation of pulmonary goblet cell differentiation|up regulation of lung goblet cell differentiation|activation of pulmonary goblet cell differentiation|activation of lung goblet cell differentiation|up-regulation of pulmonary goblet cell differentiation|up regulation of pulmonary goblet cell differentiation|up-regulation of lung goblet cell differentiation						vk	2012-08-08T08:59:44Z						biological_process											owl:Class	
GO:0009382	biolink:NamedThing	imidazoleglycerol-phosphate synthase complex	Complex that possesses imidazoleglycerol-phosphate synthase activity.	got7fsn_ti	imidazoleglycerol phosphate synthase complex				See also the molecular function term 'imidazoleglycerol-phosphate synthase activity ; GO:0000107'.									cellular_component											owl:Class	
GO:0009332	biolink:NamedThing	glutamate-tRNA ligase complex	An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu).	got7fsn_ti														cellular_component											owl:Class	
GO:0002930	biolink:NamedThing	trabecular meshwork development	The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.	got7fsn_ti							hjd	2012-04-19T04:50:06Z						biological_process											owl:Class	
GO:0043010	biolink:NamedThing	camera-type eye development	The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.	got7fsn_ti											GO:0031075|GO:0001747			biological_process											owl:Class	
GO:0010008	biolink:NamedThing	endosome membrane	The lipid bilayer surrounding an endosome.	got7fsn_ti	endosomal membrane											NIF_Subcellular:sao978443756		cellular_component											owl:Class	
GO:0072241	biolink:NamedThing	metanephric DCT cell development	The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure.	got7fsn_ti	metanephric distal convoluted tubule cell development						mah	2010-03-19T03:26:44Z						biological_process											owl:Class	
GO:0071507	biolink:NamedThing	pheromone response MAPK cascade	A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion.	got7fsn_ti	conjugation with cellular fusion, MAPKKK cascade|MAPKKK cascade involved in conjugation with cellular fusion|MAPK signaling in response to pheromone|pheromone MAPK module|MAPKKK cascade involved in mating response|MAPK cascade involved in conjugation with cellular fusion|Fus3 signaling cascade						mah	2010-01-05T01:43:47Z						biological_process											owl:Class	
GO:0000750	biolink:NamedThing	pheromone-dependent signal transduction involved in conjugation with cellular fusion	A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	transduction of mating signal										GO:0030454|GO:0007330			biological_process											owl:Class	
GO:0001609	biolink:NamedThing	G protein-coupled adenosine receptor activity	Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	A1 adenosine receptor activity, G-protein coupled|G protein coupled A1 adenosine receptor activity|adenosine receptor activity, G protein coupled|A1 adenosine receptor activity, G protein coupled|P1 receptor|A2A adenosine receptor activity, G-protein coupled|G protein coupled A2A adenosine receptor activity|G-protein-coupled A2A adenosine receptor activity|A2A adenosine receptor activity, G protein coupled|G protein coupled A2B adenosine receptor activity|G-protein-coupled A1 adenosine receptor activity|G-protein-coupled A3 adenosine receptor activity|A3 adenosine receptor activity, G protein coupled|A3 adenosine receptor activity, G-protein coupled|G-protein coupled adenosine receptor activity|G-protein-coupled A2B adenosine receptor activity|A2B adenosine receptor activity, G-protein coupled|adenosine nucleotide receptor|G protein coupled A3 adenosine receptor activity|A2B adenosine receptor activity, G protein coupled|G protein coupled adenosine receptor activity|adenosine receptor activity, G-protein coupled										GO:0001611|GO:0001612|GO:0001610|GO:0008501|GO:0001613			molecular_function											owl:Class	
GO:0001973	biolink:NamedThing	G protein-coupled adenosine receptor signaling pathway	The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.	got7fsn_ti	adenosine receptor signaling pathway, G-protein coupled|adenosine receptor signalling pathway|P1 receptor signaling pathway|adenosine receptor signaling pathway													biological_process											owl:Class	
GO:0098026	biolink:NamedThing	virus tail, tube	The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm.	got7fsn_ti	bacteriophage tail tube				Applies in particular the Myoviridae bacteriophages.		bm	2012-07-19T14:21:28Z						cellular_component											owl:Class	
GO:0098015	biolink:NamedThing	virus tail	Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell.	got7fsn_ti	viral tail|bacteriophage tail				Many bacteriophages with dsDNA genomes, or Caudovirales, have a tail. The viral tail can be short (Podoviridae), long and non-contractile (Siphoviridae) or long and contractile (Myoviridae). The tail is the channel through which the phage genome is injected into the host bacterial cell.		bm	2012-07-18T17:04:46Z						cellular_component											owl:Class	
GO:0000440	biolink:NamedThing	core TFIIH complex portion of NEF3 complex	The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3).	got7fsn_ti	SSL2-core TFIIH complex portion of NEF3 complex										GO:0000442			cellular_component											owl:Class	
GO:0044604	biolink:NamedThing	ABC-type phytochelatin transporter activity	Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.	got7fsn_ti	phytochelatin transmembrane transporter activity|ATP-dependent phytochelatin transmembrane transporter activity|ABC-type phytochelatin transmembrane transporter activity|phytochelatin transmembrane transporter ATPase activity|cadystin transmembrane transporter activity|ATPase-coupled phytochelatin transmembrane transporter activity|phytochelatin transporter activity|cadystin transmembrane transporter ATPase activity|cadystin transporter activity	https://github.com/geneontology/go-ontology/issues/14492					jl	2010-10-25T01:00:17Z			GO:0071992|GO:0071991			molecular_function											owl:Class	
GO:0071994	biolink:NamedThing	phytochelatin transmembrane transport	The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.	got7fsn_ti	phytochelatin membrane transport|cadystin transmembrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-10-25T01:58:50Z						biological_process											owl:Class	
NCBITaxon:6072	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061356	biolink:NamedThing	regulation of Wnt protein secretion	Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell.	got7fsn_ti							dph	2010-10-08T01:09:51Z						biological_process											owl:Class	
GO:0007399	biolink:NamedThing	nervous system development	The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.	got7fsn_ti	pan-neural process													biological_process											owl:Class	
GO:0008558	biolink:NamedThing	ABC-type guanine transporter activity	Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in).	got7fsn_ti	guanine ABC transporter|guanine-transporting ATPase activity|ATP-dependent guanine transmembrane transporter activity|ATPase-coupled guanine transmembrane transporter activity											RHEA:20832|EC:7.6.2.6|MetaCyc:3.6.3.37-RXN		molecular_function											owl:Class	
GO:1903716	biolink:NamedThing	guanine transmembrane transport	The process in which guanine is transported across a membrane.	got7fsn_ti							vw	2014-12-08T12:18:27Z						biological_process											owl:Class	
GO:0048477	biolink:NamedThing	oogenesis	The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.	got7fsn_ti	ovum development										GO:0048157|GO:0009993	Wikipedia:Oogenesis		biological_process											owl:Class	
GO:0039625	biolink:NamedThing	viral inner capsid	The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions.	got7fsn_ti	inner capsid						bf	2012-07-18T04:05:35Z						cellular_component											owl:Class	
GO:0048587	biolink:NamedThing	regulation of short-day photoperiodism, flowering	Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	got7fsn_ti														biological_process											owl:Class	
GO:0036014	biolink:NamedThing	cyanelle intermembrane space	The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer.	got7fsn_ti	cyanelle envelope lumen|cyanelle periplasm						bf	2011-10-10T02:12:28Z						cellular_component											owl:Class	
GO:0033112	biolink:NamedThing	cyanelle envelope	The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	got7fsn_ti														cellular_component											owl:Class	
GO:1990270	biolink:NamedThing	platelet-derived growth factor receptor-ligand complex	A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes.	got7fsn_ti	PDGF-DD-receptor alpha-beta complex|PDGF receptor-ligand complex|PDGF-CC-receptor alpha complex|PDGF-DD-receptor beta complex|PDGF-CC-receptor alpha-beta complex|receptor-ligand complex|PDGF-BB-receptor beta complex|PDGF-BB-receptor alpha-beta complex|PDGF-AB-receptor beta complex|PDGF-CC-receptor beta complex|PDGF-AA-receptor alpha complex|PDGF-BB-receptor alpha complex|PDGF complex|PDGF-AB-receptor alpha complex				An example of this is PDGFA-PGFRA in human (UniProt symbols P04085, P16234) in PMID:7679113 (inferred from direct assay).		bhm	2014-01-14T11:12:22Z						cellular_component											owl:Class	
GO:0061497	biolink:NamedThing	inner plaque of mitotic spindle pole body	One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus.	got7fsn_ti							dph	2012-12-11T09:15:12Z						cellular_component											owl:Class	
GO:0044732	biolink:NamedThing	mitotic spindle pole body	The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.	got7fsn_ti							jl	2012-11-06T15:44:02Z						cellular_component											owl:Class	
GO:0010849	biolink:NamedThing	regulation of proton-transporting ATPase activity, rotational mechanism	Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.	got7fsn_ti	regulation of hydrogen ion transporting ATPase activity, rotational mechanism|regulation of V-type ATPase activity													biological_process											owl:Class	
GO:1902600	biolink:NamedThing	proton transmembrane transport	The directed movement of a proton across a membrane.	got7fsn_ti	hydrogen transmembrane transport|hydrogen ion transmembrane transport|proton transport|proton transmembrane transport|hydrogen transport|passive proton transport, down the electrochemical gradient|ATP hydrolysis coupled proton transport|hydrogen ion transport						pr	2013-12-20T11:08:37Z			GO:0006818|GO:0015992|GO:0015991			biological_process											owl:Class	
GO:0072057	biolink:NamedThing	inner stripe development	The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.	got7fsn_ti							mah	2010-01-25T04:01:58Z						biological_process											owl:Class	
GO:0072054	biolink:NamedThing	renal outer medulla development	The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.	got7fsn_ti	outer renal medulla development						mah	2010-01-25T04:00:42Z						biological_process											owl:Class	
GO:2000228	biolink:NamedThing	positive regulation of pancreatic A cell differentiation	Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.	got7fsn_ti	positive regulation of pancreatic alpha cell differentiation						mah	2010-11-09T03:43:42Z						biological_process											owl:Class	
GO:0005929	biolink:NamedThing	cilium	A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.	got7fsn_ti	primary cilium|microtubule-based flagellum|flagellum|eukaryotic flagellum				Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms.						GO:0072372	Wikipedia:Cilium|NIF_Subcellular:sao787716553|FMA:67181		cellular_component											owl:Class	
GO:0030990	biolink:NamedThing	intraciliary transport particle	A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.	got7fsn_ti	intraflagellar transport particle|intraflagellar transport complex|IFT complex				Note that we deem cilia and microtubule-based flagella to be equivalent.									cellular_component											owl:Class	
GO:0060648	biolink:NamedThing	mammary gland bud morphogenesis	The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.	got7fsn_ti							dph	2009-05-29T08:42:22Z						biological_process											owl:Class	
GO:1990562	biolink:NamedThing	syndecan-syntenin-ALIX complex	An exosome complex that is assembled in the multivesicular body (MVB) membrane and chaperoned to the exosome by the ESCRT-III machinery.	got7fsn_ti	exosome complex				An example of this is SCD1 in human (UniProt symbol P18827) in PMID:22660413 (inferred from physical interaction).		bhm	2014-11-25T16:30:47Z						cellular_component											owl:Class	
GO:0071971	biolink:NamedThing	extracellular exosome assembly	The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm.	got7fsn_ti	extracellular vesicular exosome assembly						mah	2010-10-18T03:44:18Z						biological_process											owl:Class	
GO:0044022	biolink:NamedThing	histone kinase activity (H3-S28 specific)	Catalysis of the transfer of a phosphate group to the serine-28 residue of the N-terminal tail of histone H3.	got7fsn_ti	histone serine kinase activity (H3-S28 specific)|histone-serine kinase activity (H3-S28 specific)													molecular_function											owl:Class	
GO:0043988	biolink:NamedThing	histone H3-S28 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a serine residue at position 28 of the histone.	got7fsn_ti	histone H3 phosphorylation at S28|histone H3S28 phosphorylation													biological_process											owl:Class	
GO:0000908	biolink:NamedThing	taurine dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + O(2) + taurine = aminoacetaldehyde + CO(2) + succinate + sulfite.	got7fsn_ti	alpha-ketoglutarate-dependent taurine dioxygenase activity|taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)|2-aminoethanesulfonate dioxygenase activity											MetaCyc:RXN0-299|RHEA:15909|EC:1.14.11.17|KEGG_REACTION:R05320		molecular_function											owl:Class	
GO:0043676	biolink:NamedThing	tectum	The layer of sexine which forms a roof over the columella, granules or other infratectal elements.	got7fsn_ti	sexine 2													cellular_component											owl:Class	
GO:0106002	biolink:NamedThing	mCRD-mediated mRNA stability complex	A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP.	got7fsn_ti	mCRD-poly(A)-bridging complex|major coding region determinant of instability-mediated mRNA stability complex|major coding region instability determinant-mediated mRNA stability complex|major coding-region determinant of instability - poly(A) tail-bridging complex|major coding region instability determinant-poly(A)-bridging complex				This complex is related to GO:0070937 CRD-mediated mRNA stability complex but binds the major protein-coding-region determinant of instability (mCRD) domain rather than the CRD. Experimentally it has been shown to act on c-FOS mRNA while GO:0070937 acts on c-MYC mRNA.									cellular_component											owl:Class	
GO:1900152	biolink:NamedThing	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.	got7fsn_ti	inhibition of deadenylation-dependent mRNA decay|down regulation of mRNA degradation, deadenylation-dependent decay|inhibition of mRNA catabolism, deadenylation-dependent|down regulation of mRNA catabolic process, deadenylylation-dependent|down regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|negative regulation of mRNA catabolism, deadenylation-dependent|inhibition of mRNA catabolic process, deadenylylation-dependent|down-regulation of mRNA breakdown, deadenylation-dependent decay|downregulation of mRNA catabolic process, deadenylation-dependent|negative regulation of mRNA breakdown, deadenylation-dependent decay|negative regulation of mRNA catabolic process, deadenylation-dependent|down-regulation of mRNA catabolism, deadenylation-dependent|inhibition of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down regulation of mRNA catabolic process, deadenylation-dependent|inhibition of mRNA degradation, deadenylation-dependent decay|down-regulation of mRNA catabolism, deadenylylation-dependent|downregulation of deadenylation-dependent mRNA decay|negative regulation of mRNA catabolic process, deadenylylation-dependent|inhibition of mRNA breakdown, deadenylation-dependent decay|negative regulation of deadenylation-dependent mRNA decay|downregulation of mRNA breakdown, deadenylation-dependent decay|downregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down-regulation of deadenylation-dependent mRNA decay|down regulation of mRNA breakdown, deadenylation-dependent decay|inhibition of nuclear mRNA catabolic process, deadenylation-dependent decay|negative regulation of mRNA degradation, deadenylation-dependent decay|down regulation of mRNA catabolism, deadenylation-dependent|downregulation of mRNA degradation, deadenylation-dependent decay|downregulation of nuclear mRNA catabolic process, deadenylation-dependent decay|downregulation of mRNA catabolic process, deadenylylation-dependent|down-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|negative regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|down-regulation of mRNA catabolic process, deadenylylation-dependent|down-regulation of mRNA degradation, deadenylation-dependent decay|inhibition of mRNA catabolism, deadenylylation-dependent|inhibition of mRNA catabolic process, deadenylation-dependent|negative regulation of mRNA catabolism, deadenylylation-dependent|down regulation of deadenylation-dependent mRNA decay|down-regulation of mRNA catabolic process, deadenylation-dependent|down regulation of mRNA catabolism, deadenylylation-dependent|down-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|downregulation of mRNA catabolism, deadenylation-dependent|downregulation of mRNA catabolism, deadenylylation-dependent|down regulation of nuclear mRNA catabolic process, deadenylation-dependent decay						bf	2012-03-07T09:14:49Z						biological_process											owl:Class	
GO:0046976	biolink:NamedThing	histone methyltransferase activity (H3-K27 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group onto lysine at position 27 of the histone H3 protein.	got7fsn_ti	histone lysine N-methyltransferase activity (H3-K27 specific)|histone methylase activity (H3-K27 specific)											Reactome:R-HSA-3240295		molecular_function											owl:Class	
GO:0070734	biolink:NamedThing	histone H3-K27 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.	got7fsn_ti	histone H3K27me|histone lysine H3 K27 methylation|histone H3 K27 methylation						mah	2009-06-19T11:44:37Z						biological_process											owl:Class	
GO:0009865	biolink:NamedThing	pollen tube adhesion	The process in which the pollen tube adheres to cells of the stigma and style.	got7fsn_ti														biological_process											owl:Class	
GO:0090692	biolink:NamedThing	mitochondrial membrane scission site	The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission.	got7fsn_ti							tb	2016-08-24T10:46:09Z						cellular_component											owl:Class	
GO:1990918	biolink:NamedThing	double-strand break repair involved in meiotic recombination	The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination.	got7fsn_ti							al	2015-12-11T01:01:14Z						biological_process											owl:Class	
GO:0042166	biolink:NamedThing	acetylcholine binding	Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.	got7fsn_ti														molecular_function											owl:Class	
GO:0002430	biolink:NamedThing	complement receptor mediated signaling pathway	A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.	got7fsn_ti	immune response-regulating cell surface receptor signalling pathway|complement receptor mediated signalling pathway													biological_process											owl:Class	
GO:0061739	biolink:NamedThing	protein lipidation involved in autophagosome assembly	The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.	got7fsn_ti							dph	2015-10-14T12:02:01Z						biological_process											owl:Class	
GO:0043669	biolink:NamedThing	ectexine	The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections.	got7fsn_ti					Note that ectexine is distinguished on staining properties; compare with 'sexine ; GO:0043673'. See also 'endexine ; GO:0043671'.									cellular_component											owl:Class	
GO:1990722	biolink:NamedThing	DAPK1-calmodulin complex	A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding.	got7fsn_ti	death-associated protein kinase 1 - calmodulin complex						bhm	2015-04-01T13:05:17Z						cellular_component											owl:Class	
GO:0043065	biolink:NamedThing	positive regulation of apoptotic process	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.	got7fsn_ti	pro-apoptosis|up regulation of apoptosis|positive regulation of apoptosis|activation of apoptosis|upregulation of apoptosis|stimulation of apoptosis|up-regulation of apoptosis				This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.									biological_process											owl:Class	
GO:0044250	biolink:NamedThing	negative regulation of metabolic activity involved in hibernation	The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.	got7fsn_ti	down regulation of metabolic activity during hibernation|down-regulation of metabolic activity during hibernation|downregulation of metabolic activity during hibernation|inhibition of metabolic activity during hibernation|negative regulation of metabolic activity during hibernation													biological_process											owl:Class	
GO:0042750	biolink:NamedThing	hibernation	Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.	got7fsn_ti												Wikipedia:Hibernation		biological_process											owl:Class	
GO:0070057	biolink:NamedThing	prospore membrane spindle pole body attachment site	The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.	got7fsn_ti	forespore membrane spindle pole body attachment site|prospore membrane SPB attachment site|forespore membrane SPB attachment site													cellular_component											owl:Class	
GO:0072656	biolink:NamedThing	maintenance of protein location in mitochondrion	Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.	got7fsn_ti							mah	2011-02-14T02:30:43Z						biological_process											owl:Class	
GO:0097563	biolink:NamedThing	left middle basal body pair	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.	got7fsn_ti					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:11:14Z						cellular_component											owl:Class	
NCBITaxon:5738	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031587	biolink:NamedThing	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.	got7fsn_ti	positive regulation of IP3 receptor activity|positive regulation of inositol-1,4,5-trisphosphate receptor activity|up-regulation of IP3 receptor activity|upregulation of IP3 receptor activity|stimulation of IP3 receptor activity|up regulation of IP3 receptor activity|activation of IP3 receptor activity													biological_process											owl:Class	
GO:0051209	biolink:NamedThing	release of sequestered calcium ion into cytosol	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.	got7fsn_ti	cytosolic release of sequestered calcium ion (Ca2+)|release of sequestered calcium ion (Ca2+)|release of sequestered calcium ion into cytoplasm|release of stored calcium ion (Ca2+) into cytoplasm|release of stored calcium ion (Ca2+)|calcium ion (Ca2+) mobilization|calcium mobilization|cytosolic release of stored calcium ion (Ca2+)|cytoplasmic release of stored calcium ion (Ca2+)|cytoplasmic release of sequestered calcium ion (Ca2+)|release of stored calcium ion (Ca2+) into cytosol													biological_process											owl:Class	
GO:0036342	biolink:NamedThing	post-anal tail morphogenesis	The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.	got7fsn_ti							bf	2012-09-11T13:54:49Z						biological_process											owl:Class	
NCBITaxon:7711	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048194	biolink:NamedThing	Golgi vesicle budding	The evagination of the Golgi membrane, resulting in formation of a vesicle.	got7fsn_ti	Golgi-derived vesicle budding|dictyosome vesicle budding													biological_process											owl:Class	
GO:0002405	biolink:NamedThing	antigen sampling by dendritic cells in mucosal-associated lymphoid tissue	The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue.	got7fsn_ti	antigen sampling by dendritic cells in MALT													biological_process											owl:Class	
GO:0060657	biolink:NamedThing	regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling	Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.	got7fsn_ti	regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signalling						dph	2009-05-29T09:43:08Z						biological_process											owl:Class	
GO:0010278	biolink:NamedThing	chloroplast outer membrane translocon	The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.	got7fsn_ti														cellular_component											owl:Class	
GO:1901394	biolink:NamedThing	positive regulation of transforming growth factor beta1 activation	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation.	got7fsn_ti	up regulation of L-TGF-beta 1 activation|up-regulation of latent-TGF-beta1 activation|activation of L-TGF-beta 1 activation|up-regulation of TGFB1 activation|upregulation of TGFbeta 1 activation|upregulation of transforming growth factor-beta1 activation|positive regulation of L-TGF-beta 1 activation|upregulation of L-TGF-beta 1 activation|positive regulation of transforming growth factor-beta1 activation|up regulation of TGF-beta 1 activation|activation of transforming growth factor beta1 activation|upregulation of TGF-beta 1 activation|activation of transforming growth factor-beta1 activation|up regulation of transforming growth factor-beta1 activation|up regulation of TGFbeta 1 activation|activation of TGFB1 activation|positive regulation of latent-TGF-beta1 activation|activation of latent-TGF-beta1 activation|positive regulation of TGFB1 activation|up-regulation of L-TGF-beta 1 activation|up-regulation of TGFbeta 1 activation|up-regulation of transforming growth factor-beta1 activation|up-regulation of transforming growth factor beta1 activation|upregulation of latent-TGF-beta1 activation|upregulation of TGFB1 activation|positive regulation of TGF-beta 1 activation|positive regulation of TGFbeta 1 activation|up-regulation of TGF-beta 1 activation|up regulation of transforming growth factor beta1 activation|upregulation of transforming growth factor beta1 activation|activation of TGFbeta 1 activation|activation of TGF-beta 1 activation|up regulation of TGFB1 activation|up regulation of latent-TGF-beta1 activation						bf	2012-10-01T10:41:33Z						biological_process											owl:Class	
GO:0032905	biolink:NamedThing	transforming growth factor beta1 production	The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	TGF-B1 production|transforming growth factor-beta1 production|TGFB1 production													biological_process											owl:Class	
GO:0001946	biolink:NamedThing	lymphangiogenesis	Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.	got7fsn_ti	lymph vessel formation											Wikipedia:Lymphangiogenesis		biological_process											owl:Class	
GO:0036303	biolink:NamedThing	lymph vessel morphogenesis	The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.	got7fsn_ti							bf	2012-08-08T10:08:47Z						biological_process											owl:Class	
GO:0090267	biolink:NamedThing	positive regulation of mitotic cell cycle spindle assembly checkpoint	Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.	got7fsn_ti							tb	2010-02-05T02:09:44Z						biological_process											owl:Class	
GO:0006038	biolink:NamedThing	cell wall chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.	got7fsn_ti	cell wall chitin synthesis|cell wall chitin biosynthesis|cell wall chitin anabolism|cell wall chitin formation													biological_process											owl:Class	
NCBITaxon:89593	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034720	biolink:NamedThing	histone H3-K4 demethylation	The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone.	got7fsn_ti	H3K4 demethylation (me1 me2 and me3)													biological_process											owl:Class	
GO:0044471	biolink:NamedThing	envenomation resulting in pore formation in membrane of other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism.	got7fsn_ti							jl	2012-01-19T01:39:47Z						biological_process											owl:Class	
GO:0097649	biolink:NamedThing	A axonemal microtubule	A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule.	got7fsn_ti	A tubule						pr	2014-09-10T20:41:28Z						cellular_component											owl:Class	
GO:0010956	biolink:NamedThing	negative regulation of calcidiol 1-monooxygenase activity	Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.	got7fsn_ti							tb	2009-05-06T11:21:34Z						biological_process											owl:Class	
GO:0042368	biolink:NamedThing	vitamin D biosynthetic process	The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	got7fsn_ti	ergocalciferol biosynthetic process|vitamin D synthesis|calciferol biosynthesis|vitamin D biosynthesis|vitamin D anabolism|calciferol biosynthetic process|cholecalciferol biosynthetic process|cholecalciferol biosynthesis|vitamin D formation|ergocalciferol biosynthesis													biological_process											owl:Class	
GO:0000241	biolink:NamedThing	diakinesis	The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Meiosis#Diakinesis|Wikipedia:Diakinesis		biological_process											owl:Class	
GO:0060040	biolink:NamedThing	retinal bipolar neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.	got7fsn_ti														biological_process											owl:Class	
GO:0003407	biolink:NamedThing	neural retina development	The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.	got7fsn_ti							dph	2009-12-21T02:15:14Z						biological_process											owl:Class	
GO:0030479	biolink:NamedThing	actin cortical patch	An endocytic patch  that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.	got7fsn_ti	actin patch										GO:0005857			cellular_component											owl:Class	
GO:0000240	biolink:NamedThing	diplotene	The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Meiosis#Diplotene|Wikipedia:Diplotene		biological_process											owl:Class	
GO:0000328	biolink:NamedThing	fungal-type vacuole lumen	The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae.	got7fsn_ti	lumen of vacuole with cell cycle-correlated morphology													cellular_component											owl:Class	
GO:0090656	biolink:NamedThing	t-circle formation	A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).	got7fsn_ti	telomeric circle formation						tb	2015-07-02T11:44:23Z						biological_process											owl:Class	
GO:0034974	biolink:NamedThing	Swi5-Swi2 complex	A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching.	got7fsn_ti	Swi5 complex				Note that this term refers to Schizosaccharomyces pombe Swi5 and Swi2, which should not be confused with the unrelated Saccharomyces Swi5p and Swi2p.									cellular_component											owl:Class	
GO:0002576	biolink:NamedThing	platelet degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.	got7fsn_ti	platelet exocytosis													biological_process											owl:Class	
GO:0032324	biolink:NamedThing	molybdopterin cofactor biosynthetic process	The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.	got7fsn_ti	molybdopterin cofactor biosynthesis|molybdopterin cofactor synthesis|molybdopterin cofactor formation|molybdopterin cofactor anabolism											MetaCyc:Molybdenum-Cofactor-Biosynthesis		biological_process											owl:Class	
GO:0030366	biolink:NamedThing	molybdopterin synthase activity	Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.	got7fsn_ti												EC:2.8.1.12|Reactome:R-HSA-947541|RHEA:26333		molecular_function											owl:Class	
GO:0010431	biolink:NamedThing	seed maturation	A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.	got7fsn_ti														biological_process											owl:Class	
GO:0014021	biolink:NamedThing	secondary neural tube formation	The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals.	got7fsn_ti	medullary cord biosynthesis|neural rod formation|medullary cord formation|secondary neurulation										GO:0014026			biological_process											owl:Class	
NCBITaxon:40674	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002822	biolink:NamedThing	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.	got7fsn_ti														biological_process											owl:Class	
NCBITaxon:7776	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060318	biolink:NamedThing	definitive erythrocyte differentiation	Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis.	got7fsn_ti	definitive RBC differentiation|definitive erythropoiesis|definitive red blood cell differentiation													biological_process											owl:Class	
GO:0035564	biolink:NamedThing	regulation of kidney size	Any process that modulates the size of a kidney.	got7fsn_ti							bf	2010-07-23T11:28:22Z						biological_process											owl:Class	
GO:0010718	biolink:NamedThing	positive regulation of epithelial to mesenchymal transition	Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti														biological_process											owl:Class	
GO:0090726	biolink:NamedThing	cortical dynamic polarity patch	A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation.	got7fsn_ti	dynamic polarity patch at the cell cortex						tb	2016-11-22T16:17:02Z						cellular_component											owl:Class	
GO:0005938	biolink:NamedThing	cell cortex	The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.	got7fsn_ti	peripheral cytoplasm|cell periphery											Wikipedia:Cell_cortex		cellular_component											owl:Class	
GO:0043952	biolink:NamedThing	protein transport by the Sec complex	The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.	got7fsn_ti	protein secretion by the Sec complex|protein translocation by the Sec complex				Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'cell envelope Sec protein transport complex ; GO:0031522'. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'protein secretion by the type II secretion system ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported.									biological_process											owl:Class	
GO:0034739	biolink:NamedThing	histone deacetylase activity (H4-K16 specific)	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.	got7fsn_ti														molecular_function											owl:Class	
GO:1990178	biolink:NamedThing	HU-DNA complex	A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure.	got7fsn_ti	HU complex						bhm	2013-08-30T13:06:53Z						cellular_component											owl:Class	
GO:0043590	biolink:NamedThing	bacterial nucleoid	The region of a bacterial cell to which the DNA is confined.	got7fsn_ti														cellular_component											owl:Class	
GO:0001746	biolink:NamedThing	Bolwig's organ morphogenesis	The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.	got7fsn_ti														biological_process											owl:Class	
GO:0055034	biolink:NamedThing	Bolwig's organ development	The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.	got7fsn_ti														biological_process											owl:Class	
GO:0043055	biolink:NamedThing	maintenance of dauer	Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development.	got7fsn_ti	maintenance of dormancy in the nematode													biological_process											owl:Class	
GO:0031299	biolink:NamedThing	taurine-pyruvate aminotransferase activity	Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde.	got7fsn_ti	Tpa|taurine:pyruvate aminotransferase activity											EC:2.6.1.77|RHEA:10420|KEGG_REACTION:R05652|MetaCyc:TAURINE-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0097554	biolink:NamedThing	left anterior flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell.	got7fsn_ti	left anterior cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T12:47:41Z						cellular_component											owl:Class	
GO:0005751	biolink:NamedThing	mitochondrial respiratory chain complex IV	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).	got7fsn_ti											GO:0005752			cellular_component											owl:Class	
GO:0005746	biolink:NamedThing	mitochondrial respirasome	The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.	got7fsn_ti	mitochondrial respirasome|mitochondrial electron transport chain|mitochondrial respiratory chain supercomplex|mitochondrial respiratory chain|mitochondrial respiratory supercomplex	https://github.com/geneontology/go-ontology/issues/12846					pr	2012-02-23T05:13:54Z			GO:0097249			cellular_component											owl:Class	
GO:0010007	biolink:NamedThing	magnesium chelatase complex	A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner.	got7fsn_ti														cellular_component											owl:Class	
GO:0015214	biolink:NamedThing	pyrimidine nucleoside transmembrane transporter activity	Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0072531	biolink:NamedThing	pyrimidine-containing compound transmembrane transport	The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof.	got7fsn_ti	pyrimidine-containing compound membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2011-01-05T01:47:22Z						biological_process											owl:Class	
GO:0061562	biolink:NamedThing	cranial ganglion structural organization	The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	cranial ganglia structural organization						dph	2013-07-10T09:10:52Z						biological_process											owl:Class	
GO:0005353	biolink:NamedThing	fructose transmembrane transporter activity	Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.	got7fsn_ti	fructose permease activity|fructose porter activity										GO:0019192|GO:0015585	Reactome:R-HSA-189222		molecular_function											owl:Class	
GO:0015755	biolink:NamedThing	fructose transmembrane transport	The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.	got7fsn_ti	fructose transport													biological_process											owl:Class	
GO:1903024	biolink:NamedThing	positive regulation of ascospore-type prospore membrane formation	Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane.	got7fsn_ti	upregulation of FSM assembly|activation of ascospore-type prospore membrane assembly|upregulation of FSM biosynthesis|up-regulation of forespore membrane biosynthesis|up-regulation of FSM assembly|upregulation of ascospore-type prospore membrane assembly|positive regulation of forespore membrane formation|activation of FSM formation|positive regulation of FSM biosynthesis|upregulation of FSM formation|up-regulation of forespore membrane formation|activation of forespore membrane formation|activation of forespore membrane biosynthesis|up regulation of forespore membrane biosynthesis|positive regulation of FSM assembly|upregulation of forespore membrane biosynthesis|up regulation of forespore membrane formation|up regulation of FSM biosynthesis|positive regulation of ascospore-type prospore membrane assembly|up regulation of ascospore-type prospore membrane assembly|up regulation of FSM formation|positive regulation of FSM formation|upregulation of forespore membrane formation|up-regulation of ascospore-type prospore membrane assembly|activation of FSM biosynthesis|up-regulation of FSM formation|up-regulation of FSM biosynthesis|positive regulation of forespore membrane biosynthesis|up regulation of FSM assembly|activation of FSM assembly						al	2014-05-15T08:51:58Z						biological_process											owl:Class	
GO:0097342	biolink:NamedThing	ripoptosome	A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.	got7fsn_ti	necrosome|Tnfr1-CII|TNFR1 complex II				It has been shown that receptor-mediated necroptotic signaling pathway requires assembly of a ripoptosome protein complex consisting of caspase-8, caspase-10, Fas-associated death domain protein (FADD), casp8 and FADD-like apoptosis regulator (CFLAR) as well as the two receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (PMID:21737330). Optionally, depending on the receptor activated, this complex may contain TLR3 adaptor protein TRIF (PMID:21737330).		pr	2012-06-18T12:55:34Z						cellular_component											owl:Class	
GO:0005829	biolink:NamedThing	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	got7fsn_ti												NIF_Subcellular:sao101633890|Wikipedia:Cytosol		cellular_component											owl:Class	
GO:1990685	biolink:NamedThing	HDL-containing protein-lipid-RNA complex	A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.	got7fsn_ti					Examples of HDL-containing protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoproteins (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034364 'high-density lipoprotein particle', which describes complexes of proteins and lipids only, without RNAs.		pr	2015-03-11T14:56:52Z						cellular_component											owl:Class	
CHEBI:39025	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048620	biolink:NamedThing	post-embryonic hindgut morphogenesis	The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0007442	biolink:NamedThing	hindgut morphogenesis	The process in which the anatomical structures of the hindgut are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:2000431	biolink:NamedThing	regulation of cytokinesis, actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.	got7fsn_ti	regulation of contractile ring assembly						vw	2011-03-03T12:17:41Z						biological_process											owl:Class	
GO:0061380	biolink:NamedThing	superior colliculus development	The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.	got7fsn_ti							dph	2010-11-09T09:51:00Z						biological_process											owl:Class	
GO:0061378	biolink:NamedThing	corpora quadrigemina development	The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.	got7fsn_ti							dph	2010-11-09T09:45:36Z						biological_process											owl:Class	
GO:0002908	biolink:NamedThing	regulation of peripheral B cell deletion	Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.	got7fsn_ti														biological_process											owl:Class	
GO:0031091	biolink:NamedThing	platelet alpha granule	A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).	got7fsn_ti	platelet alpha-granule											Wikipedia:Platelet_alpha-granule		cellular_component											owl:Class	
CL:0000233	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033282	biolink:NamedThing	protein C inhibitor-acrosin complex	A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.	got7fsn_ti	PCI-ACR complex|SERPINA5-acrosin complex|plasma serine protease inhibitor-acrosin complex|serpin A5-acrosin complex|PCI-acrosin complex													cellular_component											owl:Class	
GO:0061277	biolink:NamedThing	mesonephric nephron tubule formation	The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.	got7fsn_ti							dph	2010-09-02T01:16:21Z						biological_process											owl:Class	
GO:0070916	biolink:NamedThing	inositol phosphoceramide synthase complex	A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).	got7fsn_ti	IPC synthase complex						mah	2009-09-10T05:23:21Z						cellular_component											owl:Class	
GO:0042734	biolink:NamedThing	presynaptic membrane	A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.	got7fsn_ti	pre-synaptic membrane|presynaptic plasma membrane													cellular_component											owl:Class	
GO:0042302	biolink:NamedThing	structural constituent of cuticle	The action of a molecule that contributes to the structural integrity of a cuticle.	got7fsn_ti														molecular_function											owl:Class	
GO:0140479	biolink:NamedThing	ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase	A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide.	got7fsn_ti							pg	2020-06-25T09:58:21Z						biological_process											owl:Class	
GO:0021814	biolink:NamedThing	cell motility involved in cerebral cortex radial glia guided migration	The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.	got7fsn_ti	cell locomotion involved in cerebral cortex glial-mediated radial migration|cell locomotion involved in cerebral cortex radial glia guided migration													biological_process											owl:Class	
GO:0015225	biolink:NamedThing	biotin transmembrane transporter activity	Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.	got7fsn_ti	biotin transporter activity|vitamin H transporter activity|vitamin B7 transporter activity						al	2012-11-08T14:18:56Z			GO:1901603	RHEA:28458		molecular_function											owl:Class	
GO:0015878	biolink:NamedThing	biotin transport	The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.	got7fsn_ti	vitamin H transport|vitamin B7 transport													biological_process											owl:Class	
GO:0110069	biolink:NamedThing	syncytial embryo cellularization	The separation of a syncytial embryo into individual cells.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14543					kmv	2017-11-22T19:59:19Z						biological_process											owl:Class	
GO:0030493	biolink:NamedThing	bacteriochlorophyll metabolic process	The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.	got7fsn_ti	bacteriochlorophyll metabolism													biological_process											owl:Class	
GO:0003007	biolink:NamedThing	heart morphogenesis	The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	got7fsn_ti	cardiac morphogenesis													biological_process											owl:Class	
GO:0015093	biolink:NamedThing	ferrous iron transmembrane transporter activity	Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.	got7fsn_ti	ferrous iron uptake transmembrane transporter activity										GO:0015639	Reactome:R-HSA-442368|Reactome:R-HSA-1362417|Reactome:R-HSA-5655760|RHEA:28486		molecular_function											owl:Class	
GO:0034755	biolink:NamedThing	iron ion transmembrane transport	A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	iron ion membrane transport|low-affinity iron ion transmembrane transport|high affinity ferrous ion transmembrane transport|transmembrane iron transport|high-affinity iron ion transport|high-affinity iron ion transmembrane transport|iron(2+) transmembrane transport|low affinity iron ion transport|high affinity iron ion transport|low-affinity iron ion transport|ferrous ion transmembrane transport|high-affinity ferrous ion transmembrane transport|ferrous iron transmembrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		vw	2015-02-06T11:29:22Z			GO:1903874|GO:0000040|GO:0006827|GO:0061839			biological_process											owl:Class	
GO:0016935	biolink:NamedThing	glycine-gated chloride channel complex	A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.	got7fsn_ti														cellular_component											owl:Class	
GO:0002195	biolink:NamedThing	2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis	The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs.	got7fsn_ti					In Salmonella typhimurium, 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A; also referred to as 2-methylthio cis-ribozeatin) is found in tRNA, most likely in the species that have ms2i6A in E. coli.		hjd	2011-08-31T02:20:06Z						biological_process											owl:Class	
GO:0043533	biolink:NamedThing	inositol 1,3,4,5 tetrakisphosphate binding	Binding to inositol 1,3,4,5 tetrakisphosphate.	got7fsn_ti	InsP4 binding|IP4 binding													molecular_function											owl:Class	
GO:0050833	biolink:NamedThing	pyruvate transmembrane transporter activity	Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other.	got7fsn_ti	monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity											Reactome:R-HSA-372342		molecular_function											owl:Class	
GO:0010312	biolink:NamedThing	detoxification of zinc ion	Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.	got7fsn_ti														biological_process											owl:Class	
GO:0000095	biolink:NamedThing	S-adenosyl-L-methionine transmembrane transporter activity	Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.	got7fsn_ti	S-adenosyl methionine transporter activity|S-adenosylmethionine transmembrane transporter activity|S-adenosylmethionine permease activity|S-adenosyl methionine permease activity|S-adenosylmethionine transporter activity|SAM transmembrane transporter activity										GO:0015177	Reactome:R-HSA-8855062		molecular_function											owl:Class	
GO:1901962	biolink:NamedThing	S-adenosyl-L-methionine transmembrane transport	The directed movement of S-adenosyl-L-methionine across a membrane.	got7fsn_ti	S-adenosylmethionine transmembrane transport|SAM transmembrane transport						jl	2013-02-20T14:45:08Z						biological_process											owl:Class	
GO:0061215	biolink:NamedThing	mesonephric nephron development	The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.	got7fsn_ti							dph	2010-08-17T03:31:08Z						biological_process											owl:Class	
GO:0120078	biolink:NamedThing	cell adhesion involved in sprouting angiogenesis	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network.	got7fsn_ti	cell adhesion involved in blood vessel anastomosis|cell adhesion involved in vascular anastomosis	https://github.com/geneontology/go-ontology/issues/13690					krc	2017-06-27T21:29:47Z						biological_process											owl:Class	
GO:0072660	biolink:NamedThing	maintenance of protein location in plasma membrane	Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.	got7fsn_ti							mah	2011-02-14T02:46:08Z						biological_process											owl:Class	
GO:0072659	biolink:NamedThing	protein localization to plasma membrane	A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.	got7fsn_ti	protein-plasma membrane targeting|protein localisation in plasma membrane|protein targeting to plasma membrane|protein localization in plasma membrane						tb	2009-07-10T10:29:23Z			GO:0090002|GO:0072661			biological_process											owl:Class	
GO:1903583	biolink:NamedThing	positive regulation of basophil degranulation	Any process that activates or increases the frequency, rate or extent of basophil degranulation.	got7fsn_ti	upregulation of basophil degranulation|activation of basophil degranulation|up-regulation of basophil degranulation|up regulation of basophil degranulation						sl	2014-10-31T17:37:42Z						biological_process											owl:Class	
GO:0140091	biolink:NamedThing	mBAF complex	A muscle cell-specific SWI/SNF-type complex that contains eight to fourteen proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes, and the muscle-specific product of the DPF3/BAF45C gene or an ortholog thereof.	got7fsn_ti	muscle-specific BAF complex|muscle-type SWI/SNF complex|muscle-specific SWI/SNF complex|muscle-type BAF complex						pg	2017-09-05T09:20:45Z						cellular_component											owl:Class	
GO:0098666	biolink:NamedThing	G protein-coupled serotonin receptor complex	A protein complex that is capable of G protein-coupled serotonin receptor activity.	got7fsn_ti	G-protein coupled serotonin receptor complex	https://github.com/geneontology/go-ontology/issues/12942					dos	2016-12-21T12:28:12Z						cellular_component											owl:Class	
GO:0098664	biolink:NamedThing	G protein-coupled serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.	got7fsn_ti	G-protein coupled serotonin receptor signaling pathway						dos	2016-12-21T12:07:58Z						biological_process											owl:Class	
GO:0007464	biolink:NamedThing	R3/R4 cell fate commitment	The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.	got7fsn_ti														biological_process											owl:Class	
GO:0042067	biolink:NamedThing	establishment of ommatidial planar polarity	The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.	got7fsn_ti	establishment of ommatidial polarity													biological_process											owl:Class	
GO:0072011	biolink:NamedThing	glomerular endothelium development	The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.	got7fsn_ti							mah	2010-01-25T02:02:57Z						biological_process											owl:Class	
GO:0022005	biolink:NamedThing	midbrain-hindbrain boundary maturation during neural plate development	A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	got7fsn_ti	midbrain-hindbrain boundary maturation involved in neural plate development													biological_process											owl:Class	
GO:0021732	biolink:NamedThing	midbrain-hindbrain boundary maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	got7fsn_ti	MHB maturation|isthmus maturation													biological_process											owl:Class	
GO:0072273	biolink:NamedThing	metanephric nephron morphogenesis	The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.	got7fsn_ti							mah	2010-03-30T03:33:19Z						biological_process											owl:Class	
GO:0003338	biolink:NamedThing	metanephros morphogenesis	The process in which the anatomical structures of the metanephros are generated and organized.	got7fsn_ti							dph	2009-11-24T09:32:09Z						biological_process											owl:Class	
GO:1990205	biolink:NamedThing	taurine dioxygenase complex	A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD.	got7fsn_ti	alpha-ketoglutarate-dependent taurine dioxygenase complex|2-aminoethanesulfonate dioxygenase complex|TauD complex						bhm	2013-10-07T13:03:15Z						cellular_component											owl:Class	
GO:0012507	biolink:NamedThing	ER to Golgi transport vesicle membrane	The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.	got7fsn_ti	COPII coated vesicle membrane|endoplasmic reticulum-Golgi transport vesicle membrane|ER to Golgi constitutive secretory pathway transport vesicle membrane|ER-Golgi transport vesicle membrane|endoplasmic reticulum to Golgi transport vesicle membrane										GO:0030664			cellular_component											owl:Class	
GO:0030134	biolink:NamedThing	COPII-coated ER to Golgi transport vesicle	A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).	got7fsn_ti	ER-Golgi transport vesicle|COPII-coated vesicle|COPII-associated vesicle|endoplasmic reticulum to Golgi transport vesicle|ER to Golgi transport vesicle|COPII-associated ER to Golgi transport vesicle|ER to Golgi constitutive secretory pathway transport vesicle|endoplasmic reticulum-Golgi transport vesicle|COPII vesicle						pg	2017-06-22T16:26:57Z			GO:0030138|GO:0140045			cellular_component											owl:Class	
GO:0035052	biolink:NamedThing	dorsal vessel aortic cell fate commitment	The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0035054	biolink:NamedThing	embryonic heart tube anterior/posterior pattern specification	The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.	got7fsn_ti														biological_process											owl:Class	
GO:2001192	biolink:NamedThing	negative regulation of gamma-delta T cell activation involved in immune response	Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response.	got7fsn_ti	negative regulation of gamma-delta T cell activation during immune response|negative regulation of gamma-delta T-cell activation during immune response|negative regulation of gamma-delta T-lymphocyte activation during immune response|negative regulation of gamma-delta T lymphocyte activation during immune response						yaf	2011-11-03T04:28:44Z						biological_process											owl:Class	
GO:0150034	biolink:NamedThing	distal axon	That part of an axon close to and including the growth cone or the axon terminus.	got7fsn_ti	distal part of axon|distal part of the axon						bc	2018-02-19T15:04:24Z						cellular_component											owl:Class	
GO:0120310	biolink:NamedThing	amastigogenesis	The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites.	got7fsn_ti							krc	2021-03-23T21:17:19Z						biological_process											owl:Class	
OBO:OPL_0000322	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075307	biolink:NamedThing	positive regulation of conidium formation	Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	got7fsn_ti														biological_process											owl:Class	
GO:0061890	biolink:NamedThing	positive regulation of astrocyte activation	Any process that increases the frequency, rate or extent of astrocyte activation.	got7fsn_ti							dph	2017-06-01T22:31:50Z						biological_process											owl:Class	
GO:0048708	biolink:NamedThing	astrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.	got7fsn_ti														biological_process											owl:Class	
GO:0009561	biolink:NamedThing	megagametogenesis	The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center.	got7fsn_ti	embryo sac development from the megaspore|megagametophyte nucleus division											Wikipedia:Megagametogenesis		biological_process											owl:Class	
GO:1901016	biolink:NamedThing	regulation of potassium ion transmembrane transporter activity	Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity.	got7fsn_ti	regulation of potassium transporter activity						rl	2012-06-15T01:13:49Z						biological_process											owl:Class	
GO:0097381	biolink:NamedThing	photoreceptor disc membrane	Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.	got7fsn_ti							pr	2012-10-05T11:01:22Z						cellular_component											owl:Class	
GO:0001750	biolink:NamedThing	photoreceptor outer segment	The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0098911	biolink:NamedThing	regulation of ventricular cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction.  This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti							tb	2011-11-10T07:59:36Z						biological_process											owl:Class	
GO:0034090	biolink:NamedThing	maintenance of meiotic sister chromatid cohesion	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0060504	biolink:NamedThing	positive regulation of epithelial cell proliferation involved in lung bud dilation	Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially.	got7fsn_ti														biological_process											owl:Class	
GO:0140223	biolink:NamedThing	general transcription initiation factor activity	A molecular function required for core promoter activity that mediates the assembly of the RNA polymerase holoenzyme at promoter DNA to form the pre-initiation complex (PIC). General transcription factors (GTFs) bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present at all promoters to initiate transcription. GTFs act at each promoter, although the exact subunit composition at individual promoters may vary.	got7fsn_ti	basal transcription factor activity|GTF activity|general transcription factor activity	https://github.com/geneontology/go-ontology/issues/20253			Usage guidance: The distinction between general transcription factors and DNA-binding transcription factors is that the latter modulate the selection of which genes are expressed under specific conditions, while general transcription factors are the constitutive machinery required for transcription initiation.		pg	2018-05-24T07:51:23Z						molecular_function											owl:Class	
GO:0140530	biolink:NamedThing	MCM complex loading	The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading takes place during G1 phase, and precedes CMG complex assembly.	got7fsn_ti	MCM complex loading at replication origin|MCM double hexamer formation at replication origin	https://github.com/geneontology/go-ontology/issues/16570					pg	2020-10-12T16:46:23Z						biological_process											owl:Class	
GO:1902315	biolink:NamedThing	nuclear cell cycle DNA replication initiation	Any DNA replication initiation that is involved in nuclear cell cycle DNA replication.	got7fsn_ti	DNA replication initiation involved in nuclear cell cycle DNA replication|DNA re-replication initiation involved in nuclear cell cycle DNA replication|DNA endoreduplication initiation involved in nuclear cell cycle DNA replication						jl	2013-07-23T14:00:01Z						biological_process											owl:Class	
GO:0097691	biolink:NamedThing	bacterial extracellular vesicle	Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells.	got7fsn_ti							pr	2015-09-24T11:31:44Z						cellular_component											owl:Class	
GO:0021784	biolink:NamedThing	postganglionic parasympathetic fiber development	The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.	got7fsn_ti														biological_process											owl:Class	
GO:0048486	biolink:NamedThing	parasympathetic nervous system development	The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.	got7fsn_ti														biological_process											owl:Class	
GO:0007433	biolink:NamedThing	larval salivary gland boundary specification	Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.	got7fsn_ti	larval salivary gland determination													biological_process											owl:Class	
GO:0002168	biolink:NamedThing	instar larval development	The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0060347	biolink:NamedThing	heart trabecula formation	The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.	got7fsn_ti	heart trabecula biogenesis|cardiac trabecula formation|heart trabeculation|cardiac trabeculation													biological_process											owl:Class	
GO:0021553	biolink:NamedThing	olfactory nerve development	The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	got7fsn_ti	cranial nerve 1 development|CN 1 development|cranial nerve I development													biological_process											owl:Class	
GO:2001310	biolink:NamedThing	gliotoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.	got7fsn_ti	gliotoxin synthesis|gliotoxin anabolism|gliotoxin formation|gliotoxin biosynthesis						pr	2012-03-15T03:42:18Z						biological_process											owl:Class	
GO:1905607	biolink:NamedThing	negative regulation of presynapse assembly	Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly.	got7fsn_ti	negative regulation of presynapse biogenesis|down regulation of presynapse biogenesis|negative regulation of presynaptic terminal assembly|inhibition of presynaptic terminal assembly|down-regulation of presynaptic terminal assembly|down regulation of presynaptic terminal assembly|inhibition of presynapse biogenesis|downregulation of presynapse assembly|down-regulation of presynapse biogenesis|downregulation of presynaptic terminal assembly|down regulation of presynapse assembly|inhibition of presynapse assembly|down-regulation of presynapse assembly|downregulation of presynapse biogenesis						bc	2016-10-27T16:08:20Z						biological_process											owl:Class	
GO:0001712	biolink:NamedThing	ectodermal cell fate commitment	The cell differentiation process that results in commitment of a cell to become part of the ectoderm.	got7fsn_ti	ectoderm cell fate commitment													biological_process											owl:Class	
GO:0007286	biolink:NamedThing	spermatid development	The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.	got7fsn_ti	spermatid cell development|spermiogenesis											Wikipedia:Spermiogenesis		biological_process											owl:Class	
GO:1990354	biolink:NamedThing	activated SUMO-E1 ligase complex	A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins.	got7fsn_ti	SUMO-SAE1/2 complex				An example of this is SAE1 in human (UniProt symbol Q9UBE0) in PMID:15660128 (inferred from direct assay).		bhm	2014-03-31T13:22:45Z						cellular_component											owl:Class	
GO:0031510	biolink:NamedThing	SUMO activating enzyme complex	A conserved heterodimeric complex with SUMO activating enzyme activity.	got7fsn_ti	SAE|SUMO E1 activator enzyme complex													cellular_component											owl:Class	
GO:0030121	biolink:NamedThing	AP-1 adaptor complex	A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).	got7fsn_ti	HA1 clathrin adaptor|AP-1 related adapter complex|HA1													cellular_component											owl:Class	
GO:0035147	biolink:NamedThing	branch fusion, open tracheal system	Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.	got7fsn_ti	tracheal branch fusion													biological_process											owl:Class	
NCBITaxon:33317	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030913	biolink:NamedThing	paranodal junction assembly	Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier.	got7fsn_ti	paranodal junction biosynthesis|paranodal junction formation|paranodal axoglial junction formation													biological_process											owl:Class	
GO:1905601	biolink:NamedThing	negative regulation of receptor-mediated endocytosis involved in cholesterol transport	Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.	got7fsn_ti	down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down regulation of receptor-mediated endocytosis involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|inhibition of receptor-mediated endocytosis involved in cholesterol transport|down-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|downregulation of receptor-mediated endocytosis involved in cholesterol transport|inhibition of receptor-mediated endocytosis involved in intracellular cholesterol transport|negative regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|inhibition of receptor-mediated endocytosis of LDL|down regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of LDL|downregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|down-regulation of receptor-mediated endocytosis of LDL|down-regulation of receptor-mediated endocytosis involved in cholesterol transport|downregulation of receptor-mediated endocytosis of LDL|down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down regulation of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport						pr	2016-10-26T13:01:52Z						biological_process											owl:Class	
GO:0032367	biolink:NamedThing	intracellular cholesterol transport	The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.	got7fsn_ti														biological_process											owl:Class	
GO:0120308	biolink:NamedThing	axonemal outer doublet assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule.	got7fsn_ti	axonemal outer doublet biogenesis|axonemal outer doublet formation|axonemal outer doublet morphogenesis|outer doublet assembly|axoneme outer doublet assembly|outer-doublet microtubule assembly	https://github.com/geneontology/go-ontology/issues/21154					krc	2021-03-23T16:28:18Z						biological_process											owl:Class	
GO:0021640	biolink:NamedThing	trochlear nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	got7fsn_ti	CN IV maturation													biological_process											owl:Class	
GO:0021558	biolink:NamedThing	trochlear nerve development	The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	got7fsn_ti	cranial nerve IV development|cranial nerve 4 development|CN IV development													biological_process											owl:Class	
GO:0099079	biolink:NamedThing	actin body	An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover.  In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin.	got7fsn_ti														cellular_component											owl:Class	
GO:1990462	biolink:NamedThing	omegasome	Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites.	got7fsn_ti							pr	2014-08-19T12:26:40Z						cellular_component											owl:Class	
GO:0012505	biolink:NamedThing	endomembrane system	A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.	got7fsn_ti												Wikipedia:Endomembrane_system		cellular_component											owl:Class	
GO:0086094	biolink:NamedThing	positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction	An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of cardiac muscle contraction through phosphorylation and enhancement of the ryanodine receptor, a calcium-activated calcium-release channel found in the membrane of the sarcoplasmic reticulum. An adrenergic receptor-activated adenylate cyclase generates cAMP. cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the ryanodine receptor (RyR). PKA-phosphorylation of RyR enhances channel activity by sensitizing the channel to cytosolic calcium. Cytosolic calcium stimulates contractile proteins to promote muscle contraction.	got7fsn_ti	adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction via ryanodine receptor phosphorylation						bf							biological_process											owl:Class	
GO:0003062	biolink:NamedThing	regulation of heart rate by chemical signal	The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine.	got7fsn_ti	chemical cardiac chronotropy|chemical signal regulation of heart contraction rate|chemical signal regulation of heart rate													biological_process											owl:Class	
GO:0009655	biolink:NamedThing	PSII associated light-harvesting complex II, core complex	The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center.	got7fsn_ti	PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex|PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex|PSII associated light-harvesting complex II, core complex, LHCIId subcomplex													cellular_component											owl:Class	
GO:0009517	biolink:NamedThing	PSII associated light-harvesting complex II	Protein-pigment complex associated with photosystem II.	got7fsn_ti	LHCII													cellular_component											owl:Class	
GO:0048009	biolink:NamedThing	insulin-like growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands.	got7fsn_ti	IGF receptor signaling pathway|IGF receptor signalling pathway													biological_process											owl:Class	
GO:0070937	biolink:NamedThing	CRD-mediated mRNA stability complex	A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.	got7fsn_ti	coding-region determinant of instability-mediated mRNA stability complex|coding-region instability determinant -mediated mRNA stability complex				See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'.		mah	2009-09-22T02:00:22Z						cellular_component											owl:Class	
GO:0044499	biolink:NamedThing	envenomation resulting in positive regulation of blood pressure in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism.	got7fsn_ti							jl	2012-02-01T02:39:06Z						biological_process											owl:Class	
GO:0033617	biolink:NamedThing	mitochondrial cytochrome c oxidase assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.	got7fsn_ti	mitochondrial respiratory chain complex IV assembly|mitochondrial cytochrome c oxidase complex assembly|mitochondrial cytochrome c oxidase biogenesis													biological_process											owl:Class	
NCBITaxon:50557	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071053	biolink:NamedThing	alpha9-beta1 integrin-ADAM2 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.	got7fsn_ti	ITGA9-ITGB1-ADAM2 complex						mah	2009-11-03T03:58:22Z						cellular_component											owl:Class	
GO:0048738	biolink:NamedThing	cardiac muscle tissue development	The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.	got7fsn_ti	heart muscle development													biological_process											owl:Class	
GO:0052928	biolink:NamedThing	CTP:3'-cytidine-tRNA cytidylyltransferase activity	Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate.	got7fsn_ti												EC:2.7.7.72|KEGG_REACTION:R09384		molecular_function											owl:Class	
GO:0010368	biolink:NamedThing	chloroplast isoamylase complex	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized.	got7fsn_ti														cellular_component											owl:Class	
GO:1990851	biolink:NamedThing	Wnt-Frizzled-LRP5/6 complex	A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6.	got7fsn_ti	WNT-FZD-LRP5 complex|Wnt.Fz.LRP ternary complex|Fz/Wnt/LRP6 complex|Wnt receptor complex|Wnt-FZD-LRP5/6 trimeric complex|WNT-FZD-LRP6 complex|Frizzled-LRP5/6 complex|Wnt-induced Frizzled-LRP5/6 complex				Given the number of Wnt proteins, Frizzled proteins and LRP proteins, many different trimeric complexes are likely to form.		bf	2015-09-14T15:59:54Z						cellular_component											owl:Class	
GO:0021745	biolink:NamedThing	nucleus ambiguus development	The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0021550	biolink:NamedThing	medulla oblongata development	The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	got7fsn_ti	myelencephalon development|medulla development													biological_process											owl:Class	
GO:0033353	biolink:NamedThing	S-adenosylmethionine cycle	A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.	got7fsn_ti	SAM cycle|activated methyl cycle											MetaCyc:PWY-5041		biological_process											owl:Class	
CHEBI:57844	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051300	biolink:NamedThing	spindle pole body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.	got7fsn_ti	spindle pole body maturation|SPB organization|spindle pole body organisation|spindle pole body organization and biogenesis|SPB maturation										GO:0051426			biological_process											owl:Class	
GO:0020005	biolink:NamedThing	symbiont-containing vacuole membrane	The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.	got7fsn_ti	parasitophorous vacuolar membrane													cellular_component											owl:Class	
GO:0020003	biolink:NamedThing	symbiont-containing vacuole	Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont.	got7fsn_ti	Salmonella-containing vacuole|bacterium-containing vacuole|pathogen-occupied vacuole|parasitophorous vacuole|SCV				Note that this term does not have a relationship to 'vacuole ; GO:0005773' because it does not fit the definition of a vacuole; the parasitophorous vacuole was so named because it resembles a vacuole in the microscope.									cellular_component											owl:Class	
GO:0031164	biolink:NamedThing	contractile vacuolar membrane	The lipid bilayer surrounding the contractile vacuole.	got7fsn_ti	contractile vacuole membrane													cellular_component											owl:Class	
GO:0048226	biolink:NamedThing	Casparian strip	Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants.	got7fsn_ti												Wikipedia:Casparian_strip		cellular_component											owl:Class	
GO:0005615	biolink:NamedThing	extracellular space	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.	got7fsn_ti	intercellular space				Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term.							NIF_Subcellular:sao1425028079		cellular_component											owl:Class	
GO:0044754	biolink:NamedThing	autolysosome	A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.	got7fsn_ti	autophagolysosome|degrading autophagic vacuole|AVd						jl	2012-11-27T15:42:12Z				NIF_Subcellular:sao8444068431		cellular_component											owl:Class	
GO:0014900	biolink:NamedThing	muscle hyperplasia	A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ.	got7fsn_ti														biological_process											owl:Class	
UBERON:0002385	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990389	biolink:NamedThing	CUE1-UBC7 ubiquitin-conjugating enzyme complex	A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1.	got7fsn_ti	CUE1-UBC7 ubiquitin-conjugating enzyme (E2)				An example of this is UBC7 in Saccharomyces cerevisiae (Q02159) in PMID:16179953 (inferred from direct assay).		bhm	2014-06-02T15:35:58Z						cellular_component											owl:Class	
GO:0042637	biolink:NamedThing	catagen	The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced.	got7fsn_ti	hair regression				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0048820	biolink:NamedThing	hair follicle maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.	got7fsn_ti														biological_process											owl:Class	
GO:0032121	biolink:NamedThing	meiotic attachment of telomeric heterochromatin to spindle pole body	The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation.	got7fsn_ti	attachment of telomeric chromatin to spindle pole body|attachment of telomeres to spindle pole body													biological_process											owl:Class	
GO:0045141	biolink:NamedThing	meiotic telomere clustering	The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis.	got7fsn_ti	bouquet biosynthesis|bouquet formation													biological_process											owl:Class	
GO:0045186	biolink:NamedThing	zonula adherens assembly	Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.	got7fsn_ti														biological_process											owl:Class	
GO:0043297	biolink:NamedThing	apical junction assembly	The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.	got7fsn_ti	apical junction complex assembly													biological_process											owl:Class	
GO:0044200	biolink:NamedThing	host cell nuclear membrane	Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space.	got7fsn_ti							jl	2009-10-21T10:59:08Z						cellular_component											owl:Class	
GO:0035209	biolink:NamedThing	pupal development	The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.	got7fsn_ti														biological_process											owl:Class	
GO:0052887	biolink:NamedThing	7,9,9'-tricis-neurosporene:quinone oxidoreductase activity	Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol.	got7fsn_ti	zeta-carotene desaturase activity|9,9'-di-cis-zeta-carotene desaturase activity|ZDS activity											EC:1.3.5.6|MetaCyc:RXN-11357|KEGG_REACTION:R09658		molecular_function											owl:Class	
GO:2000632	biolink:NamedThing	negative regulation of pre-miRNA processing	Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing.	got7fsn_ti	negative regulation of pre-microRNA processing						dph	2011-04-18T03:50:19Z						biological_process											owl:Class	
GO:0035196	biolink:NamedThing	production of miRNAs involved in gene silencing by miRNA	Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.	got7fsn_ti	microRNA metabolic process|microRNA processing|microRNA metabolism|microRNA biosynthetic process|microRNA-mediated gene silencing, production of microRNAs|miRNA biogenesis|microRNA biogenesis|miRNA-mediated gene silencing, production of miRNAs|miRNA processing|gene silencing by miRNA, production of miRNAs|microRNA biosynthesis|production of microRNAs involved in gene silencing by microRNA										GO:0030918			biological_process											owl:Class	
GO:0035242	biolink:NamedThing	protein-arginine omega-N asymmetric methyltransferase activity	Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.	got7fsn_ti	S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega-dimethyl-L-arginine-forming)|type I PRMT activity|type I protein arginine methyltransferase activity				Note that type I protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N asymmetric methyltransferase activity ; GO:0035242'.							RESID:AA0068|RESID:AA0069|RHEA:48096|EC:2.1.1.319		molecular_function											owl:Class	
GO:0019919	biolink:NamedThing	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.	got7fsn_ti	peptidyl-arginine methylation, to unsymmetrical-dimethyl arginine											RESID:AA0069|RESID:AA0068		biological_process											owl:Class	
GO:0005917	biolink:NamedThing	nephrocyte diaphragm	A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates.	got7fsn_ti	nephrocyte junction													cellular_component											owl:Class	
GO:0033292	biolink:NamedThing	T-tubule organization	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.	got7fsn_ti	transverse tubule organization|T-tubule organisation|T-tubule organization and biogenesis													biological_process											owl:Class	
GO:0055001	biolink:NamedThing	muscle cell development	The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.	got7fsn_ti	muscle fiber development|myofibre development|myofiber development|muscle fibre development										GO:0048747			biological_process											owl:Class	
GO:0046972	biolink:NamedThing	histone acetyltransferase activity (H4-K16 specific)	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4.	got7fsn_ti	histone lysine acetyltransferase activity (H4-K16 specific)													molecular_function											owl:Class	
GO:0043984	biolink:NamedThing	histone H4-K16 acetylation	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.	got7fsn_ti	histone H4 acetylation at K16													biological_process											owl:Class	
GO:0055014	biolink:NamedThing	atrial cardiac muscle cell development	The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.	got7fsn_ti	atrial cardiomyocyte development|atrial heart muscle development													biological_process											owl:Class	
GO:0055011	biolink:NamedThing	atrial cardiac muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.	got7fsn_ti	atrial heart muscle cell differentiation|atrial cardiomyocyte differentiation													biological_process											owl:Class	
GO:0090131	biolink:NamedThing	mesenchyme migration	The process in which the population of cells that make up a mesenchyme undergo directed movement.	got7fsn_ti							tb	2009-12-07T03:15:17Z						biological_process											owl:Class	
GO:0097006	biolink:NamedThing	regulation of plasma lipoprotein particle levels	Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.	got7fsn_ti	plasma lipoprotein particle homeostasis						pr	2011-03-15T09:52:53Z						biological_process											owl:Class	
GO:0004694	biolink:NamedThing	eukaryotic translation initiation factor 2alpha kinase activity	Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0002552	biolink:NamedThing	serotonin secretion by mast cell	The regulated release of serotonin by a mast cell or group of mast cells.	got7fsn_ti	serotonin release by mast cell													biological_process											owl:Class	
GO:0046536	biolink:NamedThing	dosage compensation complex	A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes.	got7fsn_ti														cellular_component											owl:Class	
GO:0048593	biolink:NamedThing	camera-type eye morphogenesis	The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.	got7fsn_ti	camera-style eye morphogenesis										GO:0048595|GO:0048594			biological_process											owl:Class	
GO:0061841	biolink:NamedThing	high-affinity iron exporter complex	A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment.	got7fsn_ti	high affinity iron exporter complex|FET5-FTH1 high affinity iron exporter complex|FET5-FTH1 high-affinity iron exporter complex				An example of this is FET5 in Saccharomyces cerevisiae (P43561) in PMID:9413439.									cellular_component											owl:Class	
GO:0030867	biolink:NamedThing	rough endoplasmic reticulum membrane	The lipid bilayer surrounding the rough endoplasmic reticulum.	got7fsn_ti	RER membrane|rough ER membrane											NIF_Subcellular:sao3089754107		cellular_component											owl:Class	
GO:0070971	biolink:NamedThing	endoplasmic reticulum exit site	An endoplasmic reticulum part at which COPII-coated vesicles are produced.	got7fsn_ti	ER exit site|transitional ER						mah	2009-10-02T12:19:23Z				NIF_Subcellular:sao124393998		cellular_component											owl:Class	
GO:0010062	biolink:NamedThing	negative regulation of trichoblast fate specification	Any process that suppresses trichoblast fate specification.	got7fsn_ti	downregulation of trichoblast fate|inhibition of trichoblast fate|down regulation of trichoblast fate|down-regulation of trichoblast fate													biological_process											owl:Class	
GO:0090627	biolink:NamedThing	plant epidermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell.	got7fsn_ti							tb	2015-02-05T14:23:28Z						biological_process											owl:Class	
GO:0000379	biolink:NamedThing	tRNA-type intron splice site recognition and cleavage	RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.	got7fsn_ti														biological_process											owl:Class	
GO:0006388	biolink:NamedThing	tRNA splicing, via endonucleolytic cleavage and ligation	Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.	got7fsn_ti	tRNA-Y splicing				Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.									biological_process											owl:Class	
GO:0007477	biolink:NamedThing	notum development	The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0030878	biolink:NamedThing	thyroid gland development	The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.	got7fsn_ti														biological_process											owl:Class	
GO:0045122	biolink:NamedThing	aflatoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.	got7fsn_ti	aflatoxin synthesis|aflatoxin anabolism|aflatoxin biosynthesis|aflatoxin formation													biological_process											owl:Class	
GO:0042469	biolink:NamedThing	versicolorin reductase activity	Catalysis of the reduction of versicolorin A to sterigmatocystin.	got7fsn_ti														molecular_function											owl:Class	
GO:0055087	biolink:NamedThing	Ski complex	A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p.	got7fsn_ti												Wikipedia:Ski_complex		cellular_component											owl:Class	
GO:0061229	biolink:NamedThing	mesonephric juxtaglomerulus cell development	The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-08-19T02:34:25Z						biological_process											owl:Class	
GO:0061207	biolink:NamedThing	mesonephric juxtaglomerulus cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.	got7fsn_ti							dph	2010-08-19T12:54:08Z						biological_process											owl:Class	
GO:1903187	biolink:NamedThing	negative regulation of vitellogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis.	got7fsn_ti	inhibition of vitellogenesis|inhibition of yolk production|downregulation of vitellogenesis|down regulation of yolk production|down-regulation of yolk production|down regulation of vitellogenesis|downregulation of yolk production|down-regulation of vitellogenesis|negative regulation of yolk production						mr	2014-07-14T19:28:06Z						biological_process											owl:Class	
GO:0060437	biolink:NamedThing	lung growth	The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.	got7fsn_ti														biological_process											owl:Class	
GO:0001123	biolink:NamedThing	transcription initiation from bacterial-type RNA polymerase promoter	Any process involved in the assembly of bacterial-type RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.	got7fsn_ti							krc	2010-12-06T03:40:12Z						biological_process											owl:Class	
GO:0015629	biolink:NamedThing	actin cytoskeleton	The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.	got7fsn_ti														cellular_component											owl:Class	
GO:0000079	biolink:NamedThing	regulation of cyclin-dependent protein serine/threonine kinase activity	Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.	got7fsn_ti	regulation of cyclin-dependent protein kinase activity|regulation of CDK activity													biological_process											owl:Class	
GO:0032543	biolink:NamedThing	mitochondrial translation	The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.	got7fsn_ti	mitochondrial protein synthesis|mitochondrial protein biosynthesis|mitochondrial protein anabolism|mitochondrial protein translation|mitochondrial protein formation													biological_process											owl:Class	
GO:0000137	biolink:NamedThing	Golgi cis cisterna	The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.	got7fsn_ti														cellular_component											owl:Class	
GO:0090317	biolink:NamedThing	negative regulation of intracellular protein transport	Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.	got7fsn_ti							tb	2010-04-16T03:45:07Z						biological_process											owl:Class	
GO:1901667	biolink:NamedThing	negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration.	got7fsn_ti	down-regulation of satellite cell activation involved in skeletal muscle regeneration|inhibition of satellite cell activation involved in skeletal muscle regeneration|down regulation of satellite cell activation involved in skeletal muscle regeneration|downregulation of satellite cell activation involved in skeletal muscle regeneration						dph	2012-11-21T16:21:11Z						biological_process											owl:Class	
GO:0034462	biolink:NamedThing	small-subunit processome assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome.	got7fsn_ti	small subunit processome assembly|SSU processome assembly													biological_process											owl:Class	
GO:0000028	biolink:NamedThing	ribosomal small subunit assembly	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.	got7fsn_ti	30S ribosomal subunit assembly|40S ribosomal subunit assembly													biological_process											owl:Class	
GO:0089721	biolink:NamedThing	phosphoenolpyruvate transmembrane transporter activity	Enables the transfer of a phosphoenolpyruvate from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0089722	biolink:NamedThing	phosphoenolpyruvate transmembrane transport	The directed movement of phosphoenolpytuvate across a membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0043325	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate binding	Binding to phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.	got7fsn_ti														molecular_function											owl:Class	
NCBITaxon:6231	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0110078	biolink:NamedThing	TTT complex	A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209).	got7fsn_ti	Tel2-Tti1-Tti2|Triple T complex|TELO2-TTI1-TTI2						kmv	2018-01-29T21:39:52Z						cellular_component											owl:Class	
GO:0050821	biolink:NamedThing	protein stabilization	Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.	got7fsn_ti	protein stabilization activity|protein sequestering|protein stabilisation|positive regulation of protein stability|lysosomal protein stabilization													biological_process											owl:Class	
GO:0097268	biolink:NamedThing	cytoophidium	A subcellular filamentary structure where CTP synthase is compartmentalized in a range of organisms including bacteria, yeast, fruit fly, rat and human.	got7fsn_ti							pr	2012-03-15T01:00:20Z						cellular_component											owl:Class	
CL:0000000	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003157	biolink:NamedThing	endocardium development	The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	got7fsn_ti							dph	2009-10-01T12:42:27Z						biological_process											owl:Class	
GO:0061697	biolink:NamedThing	protein-glutaryllysine deglutarylase activity	Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.	got7fsn_ti					This reaction is the removal of a glutaryl group from a glutarylated lysine residue of a protein or peptide.		dph	2015-05-07T10:55:53Z				RHEA:47664		molecular_function											owl:Class	
GO:0061699	biolink:NamedThing	peptidyl-lysine deglutarylation	The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein.	got7fsn_ti							dph	2015-05-07T11:04:42Z						biological_process											owl:Class	
GO:0061075	biolink:NamedThing	positive regulation of neural retina development	Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.	got7fsn_ti							dph	2010-03-16T11:59:48Z						biological_process											owl:Class	
GO:0060041	biolink:NamedThing	retina development in camera-type eye	The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.	got7fsn_ti	retina development in camera-style eye|retinal development										GO:0002073			biological_process											owl:Class	
CHEBI:3098	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140266	biolink:NamedThing	Woronin body	Peroxisome-derived dense-core vesicle that seals septal pores upon hyphal lysis to prevent excessive cytoplasmic loss. It is specific to several genera of filamentous ascomycetes.	got7fsn_ti							pg	2018-09-24T14:53:37Z						cellular_component											owl:Class	
NCBITaxon:4890	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032821	biolink:NamedThing	negative regulation of natural killer cell proliferation involved in immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response.	got7fsn_ti	down regulation of natural killer cell proliferation during immune response|negative regulation of NK cell proliferation during immune response|negative regulation of natural killer cell proliferation during immune response|downregulation of natural killer cell proliferation during immune response|down-regulation of natural killer cell proliferation during immune response|inhibition of natural killer cell proliferation during immune response													biological_process											owl:Class	
GO:0016198	biolink:NamedThing	axon choice point recognition	The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth.	got7fsn_ti														biological_process											owl:Class	
GO:0005862	biolink:NamedThing	muscle thin filament tropomyosin	A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments.	got7fsn_ti														cellular_component											owl:Class	
GO:0005823	biolink:NamedThing	central plaque of spindle pole body	One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0031913	biolink:NamedThing	contractile vacuole pore	Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.	got7fsn_ti														cellular_component											owl:Class	
GO:0007606	biolink:NamedThing	sensory perception of chemical stimulus	The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti	chemosensory perception													biological_process											owl:Class	
GO:1990198	biolink:NamedThing	ModE complex	A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.	got7fsn_ti	ModE dimer						bhm	2013-10-01T07:28:52Z						cellular_component											owl:Class	
GO:0080143	biolink:NamedThing	regulation of amino acid export	Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle.	got7fsn_ti							dhl	2010-01-20T04:43:56Z						biological_process											owl:Class	
GO:0032973	biolink:NamedThing	amino acid export across plasma membrane	The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	amino acid export|amino acid transmembrane export|amino acid efflux						jl	2012-11-14T14:27:40Z			GO:0044746			biological_process											owl:Class	
GO:1903593	biolink:NamedThing	regulation of histamine secretion by mast cell	Any process that modulates the frequency, rate or extent of histamine secretion by mast cell.	got7fsn_ti							als	2014-11-06T13:19:09Z						biological_process											owl:Class	
GO:0006954	biolink:NamedThing	inflammatory response	The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.	got7fsn_ti	inflammation											Wikipedia:Inflammation		biological_process											owl:Class	
GO:0071712	biolink:NamedThing	ER-associated misfolded protein catabolic process	The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation.	got7fsn_ti	ER-associated misfolded protein catabolism|proteasomal protein catabolism of misfolded ER proteins|endoplasmic reticulum-associated misfolded protein catabolic process|ER-associated misfolded protein breakdown|endoplasmic reticulum-associated misfolded protein catabolism|ER-associated misfolded protein degradation				See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.		mah	2010-03-10T12:53:27Z						biological_process											owl:Class	
GO:0071218	biolink:NamedThing	cellular response to misfolded protein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.	got7fsn_ti							mah	2009-12-03T01:17:46Z						biological_process											owl:Class	
GO:0009758	biolink:NamedThing	carbohydrate utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism.	got7fsn_ti	sugar utilization										GO:0007587			biological_process											owl:Class	
GO:0007474	biolink:NamedThing	imaginal disc-derived wing vein specification	The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.	got7fsn_ti	wing vein specification													biological_process											owl:Class	
GO:0043009	biolink:NamedThing	chordate embryonic development	The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.	got7fsn_ti														biological_process											owl:Class	
GO:0000178	biolink:NamedThing	exosome (RNase complex)	A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.	got7fsn_ti	exosome (ribonucleasease complex)|exosome multienzyme ribonuclease complex				Note that this term should not be confused with 'exosome' used in the context of vesicles released from multivesicular bodies.									cellular_component											owl:Class	
GO:0001057	biolink:NamedThing	RNA polymerase IV activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase IV promoter						krc	2010-09-23T03:44:55Z						molecular_function											owl:Class	
GO:0071054	biolink:NamedThing	alpha9-beta1 integrin-ADAM3 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.	got7fsn_ti	ITGA9-ITGB1-ADAM3 complex						mah	2009-11-03T03:59:02Z						cellular_component											owl:Class	
CL:0000187	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070934	biolink:NamedThing	CRD-mediated mRNA stabilization	An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).	got7fsn_ti	coding region determinant-mediated mRNA stabilization						mah	2009-09-21T02:57:06Z						biological_process											owl:Class	
GO:0060261	biolink:NamedThing	positive regulation of transcription initiation from RNA polymerase II promoter	Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.	got7fsn_ti														biological_process											owl:Class	
GO:0061145	biolink:NamedThing	lung smooth muscle development	The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-05-25T10:46:35Z						biological_process											owl:Class	
GO:0060809	biolink:NamedThing	mesodermal to mesenchymal transition involved in gastrulation	The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.	got7fsn_ti							dph	2009-08-06T02:42:09Z						biological_process											owl:Class	
GO:0007369	biolink:NamedThing	gastrulation	A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.	got7fsn_ti												Wikipedia:Gastrulation		biological_process											owl:Class	
GO:0045273	biolink:NamedThing	respiratory chain complex II	A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.	got7fsn_ti	electron transport complex II													cellular_component											owl:Class	
GO:0045147	biolink:NamedThing	regulation of initiation of acetate catabolic process by acetate	Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.	got7fsn_ti	regulation of initiation of acetate breakdown by acetate|regulation of initiation of acetate degradation by acetate													biological_process											owl:Class	
GO:0010034	biolink:NamedThing	response to acetate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:2000552	biolink:NamedThing	negative regulation of T-helper 2 cell cytokine production	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production.	got7fsn_ti	negative regulation of Th2 cell cytokine production						ebc	2011-04-03T07:32:54Z						biological_process											owl:Class	
GO:0042878	biolink:NamedThing	D-glucarate transmembrane transporter activity	Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042870	biolink:NamedThing	D-glucarate transmembrane transport	The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	D-glucarate transport													biological_process											owl:Class	
GO:0002777	biolink:NamedThing	antimicrobial peptide biosynthetic process	The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.	got7fsn_ti														biological_process											owl:Class	
GO:0043704	biolink:NamedThing	photoreceptor cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0046552	biolink:NamedThing	photoreceptor cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.	got7fsn_ti														biological_process											owl:Class	
GO:0090730	biolink:NamedThing	Las1 complex	A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).	got7fsn_ti	Las1-Grc3-Rat1-Rai1						tb	2017-01-05T16:51:46Z						cellular_component											owl:Class	
GO:0120279	biolink:NamedThing	Z granule	A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans.	got7fsn_ti	germline granule	https://github.com/geneontology/go-ontology/issues/20108					krc	2020-10-21T18:27:05Z						cellular_component											owl:Class	
GO:0097447	biolink:NamedThing	dendritic tree	The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches.	got7fsn_ti							pr	2012-12-17T12:31:49Z				NIF_Subcellular:sao172297168		cellular_component											owl:Class	
GO:0006368	biolink:NamedThing	transcription elongation from RNA polymerase II promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.	got7fsn_ti	RNA polymerase II transcription elongation factor activity|RNA elongation from Pol II promoter													biological_process											owl:Class	
GO:0021768	biolink:NamedThing	nucleus accumbens development	The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia.	got7fsn_ti	ventral striatum development|accumbens nucleus development													biological_process											owl:Class	
GO:0021756	biolink:NamedThing	striatum development	The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.	got7fsn_ti	striate nucleus development|neostriatum development													biological_process											owl:Class	
GO:1905318	biolink:NamedThing	meiosis I spindle assembly checkpoint signaling	Any spindle assembly checkpoint that is involved in meiosis I.	got7fsn_ti	meiosis I spindle assembly checkpoint	https://github.com/geneontology/go-ontology/issues/20935					vw	2016-07-13T18:25:06Z						biological_process											owl:Class	
GO:0097564	biolink:NamedThing	right lateral basal body pair	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.	got7fsn_ti					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:12:42Z						cellular_component											owl:Class	
GO:1902676	biolink:NamedThing	right ventral basal body	Any ciliary basal body that is part of a right ventral flagellum found in Giardia species (trophozoite stage).	got7fsn_ti	cilium basal body of right ventral flagellum|right ventral flagellum ciliary basal body|cilial basal body of right ventral flagellum|ciliary basal body of right ventral flagellum|cilium basal body of right ventral cilium|ciliary basal body of right ventral cilium|microtubule basal body of right ventral flagellum|microtubule basal body of right ventral cilium|cilial basal body of right ventral cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:58:13Z						cellular_component											owl:Class	
GO:0005930	biolink:NamedThing	axoneme	The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.	got7fsn_ti	ciliary axoneme|flagellum axoneme|flagellar axoneme|cilium axoneme				Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.						GO:0035085|GO:0035086	Wikipedia:Axoneme		cellular_component											owl:Class	
GO:0005874	biolink:NamedThing	microtubule	Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.	got7fsn_ti	microtubulus|microtubuli|neurotubule											NIF_Subcellular:sao1846835077|Wikipedia:Microtubule		cellular_component											owl:Class	
GO:0032465	biolink:NamedThing	regulation of cytokinesis	Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.	got7fsn_ti	regulation of cell cycle cytokinesis										GO:0071775			biological_process											owl:Class	
GO:0060615	biolink:NamedThing	mammary gland bud formation	The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.	got7fsn_ti							dph	2009-05-18T08:43:14Z						biological_process											owl:Class	
GO:0052929	biolink:NamedThing	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity	Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate.	got7fsn_ti	ATP:3'-CC-tRNA adenylyltransferase activity|ATP:tRNA adenylyltransferase activity											EC:2.7.7.72|KEGG_REACTION:R09386|RHEA:60012		molecular_function											owl:Class	
GO:0004623	biolink:NamedThing	phospholipase A2 activity	Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.	got7fsn_ti	phosphatidase activity|lecithinase A activity|cytosolic phospholipase A2 activity|phosphatidolipase activity|secreted phospholipase A2 activity|phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)|phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)|phosphatidylcholine 2-acylhydrolase activity	https://github.com/geneontology/go-ontology/issues/21259									GO:0102568|GO:0102567	Reactome:R-HSA-1482604|Reactome:R-HSA-1482907|RHEA:15801|Reactome:R-HSA-1482856|MetaCyc:RXN-15067|Reactome:R-HSA-1482897|Reactome:R-HSA-1602399|Reactome:R-HSA-1602374|Reactome:R-HSA-1602377|Reactome:R-HSA-1482884|Reactome:R-HSA-1482679|Reactome:R-HSA-1602417|Reactome:R-HSA-1482825|Reactome:R-HSA-1482745|Reactome:R-HSA-1482900|Reactome:R-HSA-1482771|Reactome:R-HSA-1602398|Reactome:R-HSA-1482816|Reactome:R-HSA-1602446|Reactome:R-HSA-8848484|Reactome:R-HSA-1482759|Reactome:R-HSA-1482656|Reactome:R-HSA-1482868|EC:3.1.1.4|Reactome:R-HSA-1482776|MetaCyc:RXN-15065|Reactome:R-HSA-1602368|MetaCyc:PHOSPHOLIPASE-A2-RXN|Reactome:R-HSA-1482778|Reactome:R-HSA-1482887		molecular_function											owl:Class	
GO:0019776	biolink:NamedThing	Atg8 ligase activity	Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate.	got7fsn_ti	APG8 conjugating enzyme activity|Atg8 conjugating enzyme activity|APG8 ligase activity											Reactome:R-HSA-5681981		molecular_function											owl:Class	
GO:0019071	biolink:NamedThing	viral DNA cleavage involved in viral genome maturation	The cleavage of viral DNA into singular functional units.	got7fsn_ti														biological_process											owl:Class	
GO:0001771	biolink:NamedThing	immunological synapse formation	The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.	got7fsn_ti	formation of immunological synapse													biological_process											owl:Class	
GO:0035309	biolink:NamedThing	wing and notum subfield formation	The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.	got7fsn_ti														biological_process											owl:Class	
GO:0009854	biolink:NamedThing	oxidative photosynthetic carbon pathway	The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2).	got7fsn_ti														biological_process											owl:Class	
GO:0001885	biolink:NamedThing	endothelial cell development	The progression of an endothelial cell over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0003158	biolink:NamedThing	endothelium development	The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.	got7fsn_ti							dph	2009-10-01T12:50:57Z						biological_process											owl:Class	
GO:1901030	biolink:NamedThing	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.	got7fsn_ti	up regulation of mitochondrial outer membrane permeabilization|positive regulation of MOMP|up regulation of MOMP|positive regulation of mitochondrial outer membrane permeabilization|upregulation of mitochondrial outer membrane permeabilization|up-regulation of MOMP|upregulation of MOMP|up-regulation of mitochondrial outer membrane permeabilization|activation of mitochondrial outer membrane permeabilization|activation of MOMP				Caspase 8 may be annotated to this term when it is shown to stimulate MOMP by cleaving the BH3-only protein BID.		pr	2012-06-20T09:19:46Z						biological_process											owl:Class	
GO:0021988	biolink:NamedThing	olfactory lobe development	The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell.	got7fsn_ti														biological_process											owl:Class	
GO:1990718	biolink:NamedThing	axonemal central pair projection	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules.	got7fsn_ti							krc	2015-03-27T22:43:01Z						cellular_component											owl:Class	
GO:1990716	biolink:NamedThing	axonemal central apparatus	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules.	got7fsn_ti							krc	2015-03-27T22:33:23Z						cellular_component											owl:Class	
GO:0001542	biolink:NamedThing	ovulation from ovarian follicle	The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus.	got7fsn_ti														biological_process											owl:Class	
GO:0008585	biolink:NamedThing	female gonad development	The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.	got7fsn_ti	ovarian development|ovary development										GO:0061039			biological_process											owl:Class	
GO:0008290	biolink:NamedThing	F-actin capping protein complex	A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments.	got7fsn_ti														cellular_component											owl:Class	
GO:0086057	biolink:NamedThing	voltage-gated calcium channel activity involved in bundle of His cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated calcium channel activity involved in bundle of His cardiac muscle cell action potential						dph	2011-11-17T12:32:51Z						molecular_function											owl:Class	
GO:0086048	biolink:NamedThing	membrane depolarization during bundle of His cell action potential	The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti	membrane depolarization during bundle of His cardiac muscle cell action potential						dph	2011-11-16T10:56:26Z						biological_process											owl:Class	
GO:0002898	biolink:NamedThing	regulation of central B cell deletion	Any process that modulates the frequency, rate, or extent of central B cell deletion.	got7fsn_ti														biological_process											owl:Class	
GO:1900118	biolink:NamedThing	negative regulation of execution phase of apoptosis	Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.	got7fsn_ti	down regulation of execution phase of apoptosis|down-regulation of execution phase of apoptosis|downregulation of execution phase of apoptosis|inhibition of execution phase of apoptosis						pr	2012-02-22T11:26:24Z						biological_process											owl:Class	
GO:0030874	biolink:NamedThing	nucleolar chromatin	The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA.	got7fsn_ti														cellular_component											owl:Class	
GO:0000228	biolink:NamedThing	nuclear chromosome	A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.	got7fsn_ti	nuclear interphase chromosome													cellular_component											owl:Class	
GO:0060102	biolink:NamedThing	collagen and cuticulin-based cuticle extracellular matrix	A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans.	got7fsn_ti	collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
NCBITaxon:33213	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000018	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090558	biolink:NamedThing	plant epidermis development	The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure.	got7fsn_ti							tb	2014-02-27T15:17:37Z						biological_process											owl:Class	
GO:0000022	biolink:NamedThing	mitotic spindle elongation	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.	got7fsn_ti	microtubule sliding involved in mitotic spindle elongation|spindle elongation during mitosis						pr	2016-04-08T15:06:14Z			GO:1905121			biological_process											owl:Class	
GO:0048080	biolink:NamedThing	negative regulation of cuticle pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.	got7fsn_ti	down regulation of cuticle pigmentation|inhibition of cuticle pigmentation|down-regulation of cuticle pigmentation|downregulation of cuticle pigmentation													biological_process											owl:Class	
GO:1903669	biolink:NamedThing	positive regulation of chemorepellent activity	Any process that activates or increases the frequency, rate or extent of chemorepellent activity.	got7fsn_ti	activation of chemorepellent activity|positive regulation of chemorepellant activity|up-regulation of chemorepellant activity|upregulation of chemorepellent activity|up-regulation of chemorepellent activity|up regulation of chemorepellent activity|activation of chemorepellant activity|up regulation of chemorepellant activity|upregulation of chemorepellant activity						pf	2014-11-26T23:58:50Z						biological_process											owl:Class	
NCBITaxon:7203	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009549	biolink:NamedThing	cellulose microfibril	A microfibril composed of cellulose arranged in orthogonal layers. Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall matrix and their orientation is closely controlled by the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0009912	biolink:NamedThing	auditory receptor cell fate commitment	The process in which the cellular identity of auditory hair cells is acquired and determined.	got7fsn_ti	auditory hair cell fate commitment													biological_process											owl:Class	
GO:0042491	biolink:NamedThing	inner ear auditory receptor cell differentiation	The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.	got7fsn_ti	auditory hair cell differentiation|auditory receptor cell differentiation				Note that this term refers to the mechanosensory hair cells of the inner ear.									biological_process											owl:Class	
GO:0035215	biolink:NamedThing	genital disc development	Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia.	got7fsn_ti														biological_process											owl:Class	
GO:0031521	biolink:NamedThing	spitzenkorper	Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.	got7fsn_ti														cellular_component											owl:Class	
GO:0001411	biolink:NamedThing	hyphal tip	The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.	got7fsn_ti														cellular_component											owl:Class	
GO:1990879	biolink:NamedThing	CST complex	A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.	got7fsn_ti	CTC1-OBFC1-TEN1 complex|Cdc13-Stn1-Ten1 complex						nc	2015-10-20T13:51:07Z						cellular_component											owl:Class	
GO:0009986	biolink:NamedThing	cell surface	The external part of the cell wall and/or plasma membrane.	got7fsn_ti	cell bound|cell associated				Note that this term is intended to annotate gene products that are attached (integrated or loosely bound) to the plasma membrane or cell wall.						GO:0009929|GO:0009928			cellular_component											owl:Class	
GO:1903329	biolink:NamedThing	regulation of iron-sulfur cluster assembly	Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly.	got7fsn_ti							vw	2014-08-18T13:12:41Z						biological_process											owl:Class	
GO:1903622	biolink:NamedThing	regulation of RNA polymerase III activity	Any process that modulates the frequency, rate or extent of RNA polymerase III activity.	got7fsn_ti	regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter						al	2014-11-19T18:24:29Z						biological_process											owl:Class	
GO:0071128	biolink:NamedThing	alpha5-beta1 integrin-osteopontin complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin.	got7fsn_ti	ITGA5-ITGB1-SPP1 complex						mah	2009-11-13T02:24:43Z						cellular_component											owl:Class	
GO:0033573	biolink:NamedThing	high-affinity iron permease complex	A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity iron permease complex													cellular_component											owl:Class	
GO:0055044	biolink:NamedThing	symplast	The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata.	got7fsn_ti												Wikipedia:Symplast		cellular_component											owl:Class	
GO:0042898	biolink:NamedThing	fosmidomycin transmembrane transporter activity	Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other.	got7fsn_ti	fosmidomycin transporter activity													molecular_function											owl:Class	
GO:0042894	biolink:NamedThing	fosmidomycin transport	The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0048750	biolink:NamedThing	compound eye corneal lens morphogenesis	The process in which the anatomical structures of the compound eye corneal lens are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0043679	biolink:NamedThing	axon terminus	Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.	got7fsn_ti	nerve ending|axon terminal|axon terminal specialization											NIF_Subcellular:nlx_subcell_20090512		cellular_component											owl:Class	
GO:0050920	biolink:NamedThing	regulation of chemotaxis	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.	got7fsn_ti														biological_process											owl:Class	
GO:0045779	biolink:NamedThing	negative regulation of bone resorption	Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.	got7fsn_ti	inhibition of bone resorption|down-regulation of bone resorption|downregulation of bone resorption|down regulation of bone resorption													biological_process											owl:Class	
GO:1903133	biolink:NamedThing	negative regulation of tube lumen cavitation	Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation.	got7fsn_ti	inhibition of tube lumen cavitation						dph	2014-06-25T20:19:04Z						biological_process											owl:Class	
GO:0035153	biolink:NamedThing	epithelial cell type specification, open tracheal system	Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.	got7fsn_ti	tracheal cell type specification|tracheal epithelial cell type specification													biological_process											owl:Class	
GO:1990717	biolink:NamedThing	axonemal central bridge	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules.	got7fsn_ti							krc	2015-03-27T22:38:31Z						cellular_component											owl:Class	
GO:0044154	biolink:NamedThing	histone H3-K14 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone.	got7fsn_ti	histone H3 acetylation at K14|histone H3K14 acetylation						jl	2009-08-11T03:40:43Z						biological_process											owl:Class	
GO:0001833	biolink:NamedThing	inner cell mass cell proliferation	The proliferation of cells in the inner cell mass.	got7fsn_ti					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.									biological_process											owl:Class	
GO:0001832	biolink:NamedThing	blastocyst growth	An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.	got7fsn_ti					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'.									biological_process											owl:Class	
GO:0061357	biolink:NamedThing	positive regulation of Wnt protein secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.	got7fsn_ti							dph	2010-10-08T01:12:21Z						biological_process											owl:Class	
GO:0023052	biolink:NamedThing	signaling	The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.	got7fsn_ti	signalling|signalling process|signaling process|single organism signaling|biological signaling				Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.		jl	2010-02-16T09:30:50Z			GO:0044700|GO:0023046			biological_process											owl:Class	
GO:0043672	biolink:NamedThing	nexine	The inner, non-sculptured part of the exine which lies below the sexine.	got7fsn_ti					Note that nexine is distinguished on purely morphological criteria; compare with 'endexine ; GO:0043671'. See also 'sexine ; GO:0043673'.									cellular_component											owl:Class	
GO:0030096	biolink:NamedThing	plasma membrane-derived thylakoid photosystem II	A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.	got7fsn_ti	plasma membrane photosystem II													cellular_component											owl:Class	
GO:0010197	biolink:NamedThing	polar nucleus fusion	The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.	got7fsn_ti														biological_process											owl:Class	
GO:1990058	biolink:NamedThing	fruit replum development	The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum.	got7fsn_ti							dhl	2013-03-12T21:15:15Z						biological_process											owl:Class	
GO:1903905	biolink:NamedThing	positive regulation of establishment of T cell polarity	Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity.	got7fsn_ti	upregulation of establishment of T-cell polarity|activation of T lymphocyte polarization|upregulation of T cell polarization|upregulation of establishment of T lymphocyte polarity|positive regulation of establishment of T-lymphocyte polarity|up regulation of T lymphocyte polarization|up-regulation of establishment of T-cell polarity|upregulation of establishment of T cell polarity|up-regulation of T lymphocyte polarization|positive regulation of establishment of T lymphocyte polarity|up-regulation of T cell polarization|up regulation of T-cell polarization|positive regulation of establishment of T-cell polarity|activation of establishment of T-lymphocyte polarity|upregulation of establishment of T-lymphocyte polarity|up regulation of establishment of T lymphocyte polarity|activation of establishment of T cell polarity|up regulation of T cell polarization|up-regulation of establishment of T-lymphocyte polarity|upregulation of T-cell polarization|upregulation of T lymphocyte polarization|positive regulation of T cell polarization|up regulation of establishment of T-cell polarity|up-regulation of T-cell polarization|activation of establishment of T lymphocyte polarity|up-regulation of establishment of T lymphocyte polarity|positive regulation of T lymphocyte polarization|positive regulation of T-cell polarization|up regulation of establishment of T cell polarity|up-regulation of establishment of T cell polarity|activation of T cell polarization|activation of establishment of T-cell polarity|activation of T-cell polarization|up regulation of establishment of T-lymphocyte polarity						als	2015-02-09T10:50:40Z						biological_process											owl:Class	
GO:1990316	biolink:NamedThing	Atg1/ULK1 kinase complex	A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.	got7fsn_ti	ULK1 signaling complex|ULK1 complex|autophagy-initiation complex|ATG1/ULK1 signaling complex|ULK1-ATG13-FIP200 complex|ULK complex|Atg1p signalling complex|ATG1-ATG13 complex|ULK1-ATG13-RB1CC1 complex|ATG1 kinase complex						bhm	2014-03-14T10:55:11Z			GO:0034273|GO:0070969			cellular_component											owl:Class	
GO:0003192	biolink:NamedThing	mitral valve formation	The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti							dph	2009-10-08T01:10:19Z						biological_process											owl:Class	
GO:0003183	biolink:NamedThing	mitral valve morphogenesis	The process in which the structure of the mitral valve is generated and organized.	got7fsn_ti							dph	2009-10-08T12:02:01Z						biological_process											owl:Class	
GO:1990662	biolink:NamedThing	S100A9 complex	A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility.	got7fsn_ti	S100A9 homodimer				An example of this is S100A9 in human (UniProt symbol P06702) in PMID:15642721 (inferred from direct assay).		bhm	2015-02-25T15:55:48Z						cellular_component											owl:Class	
GO:0035662	biolink:NamedThing	Toll-like receptor 4 binding	Binding to a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	got7fsn_ti	TLR4 binding						bf	2011-02-01T10:20:59Z						molecular_function											owl:Class	
GO:1901233	biolink:NamedThing	negative regulation of convergent extension involved in axis elongation	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation.	got7fsn_ti	downregulation of convergent extension involved in axis elongation|inhibition of convergent extension involved in axis elongation|down-regulation of convergent extension involved in axis elongation|down regulation of convergent extension involved in axis elongation						vk	2012-08-07T14:22:11Z						biological_process											owl:Class	
GO:0048546	biolink:NamedThing	digestive tract morphogenesis	The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.	got7fsn_ti	gut morphogenesis|intestinal morphogenesis|gastrointestinal tract morphogenesis|alimentary canal morphogenesis|digestive tube morphogenesis										GO:0048547			biological_process											owl:Class	
GO:0021547	biolink:NamedThing	midbrain-hindbrain boundary initiation	The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	got7fsn_ti	isthmus formation|isthmus biosynthesis|midbrain-hindbrain boundary biosynthesis|midbrain-hindbrain boundary formation|MHB formation|MHB biosynthesis													biological_process											owl:Class	
GO:0060478	biolink:NamedThing	acrosomal vesicle exocytosis	The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction.	got7fsn_ti	acrosomal granule exocytosis|acrosome exocytosis													biological_process											owl:Class	
GO:0007340	biolink:NamedThing	acrosome reaction	The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.	got7fsn_ti					If the release of the acrosome content occurs before the sperm reaches the zona pellucida, consider using premature acrosome loss.							Wikipedia:Acrosome_reaction		biological_process											owl:Class	
GO:0070899	biolink:NamedThing	mitochondrial tRNA wobble uridine modification	The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified.	got7fsn_ti							mah	2009-09-02T03:14:13Z						biological_process											owl:Class	
GO:0030991	biolink:NamedThing	intraciliary transport particle A	The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.	got7fsn_ti	IFT A complex|intraflagellar transport particle A|IFT complex A|intraflagellar transport complex A				Note that we deem cilia and microtubule-based flagella to be equivalent.									cellular_component											owl:Class	
GO:0035720	biolink:NamedThing	intraciliary anterograde transport	The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.	got7fsn_ti	intraflagellar anterograde transport				Note that we deem cilium and microtubule-based flagellum to be equivalent.		bf	2011-03-07T11:24:53Z						biological_process											owl:Class	
GO:0000281	biolink:NamedThing	mitotic cytokinesis	A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.	got7fsn_ti	cytokinesis after mitosis													biological_process											owl:Class	
GO:0039532	biolink:NamedThing	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm.	got7fsn_ti	negative regulation of MAVS signaling|negative regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway|negative regulation of cytoplasmic pattern recognition receptor signaling pathway in response to virus						bf	2012-01-03T11:14:48Z						biological_process											owl:Class	
GO:0051607	biolink:NamedThing	defense response to virus	Reactions triggered in response to the presence of a virus that act to protect the cell or organism.	got7fsn_ti	defense response to viruses|defence response to virus|antiviral response													biological_process											owl:Class	
GO:0035550	biolink:NamedThing	urease complex	A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).	got7fsn_ti					Eukaryotic microorganisms, plants, and probably Gram-positive bacteria, possess a homopolymeric urease. In contrast, urease complexes from gram-negative bacteria studied thus far clearly possess three distinct subunits (alpha, beta and gamma). Tightly bound nickel is present in all urease complexes.		bf	2010-05-12T01:00:27Z						cellular_component											owl:Class	
GO:0000287	biolink:NamedThing	magnesium ion binding	Binding to a magnesium (Mg) ion.	got7fsn_ti	magnesium binding|Mg binding													molecular_function											owl:Class	
GO:0007350	biolink:NamedThing	blastoderm segmentation	The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0061474	biolink:NamedThing	phagolysosome membrane	The lipid bilayer surrounding a phagolysosome.	got7fsn_ti							dph	2012-11-06T12:26:18Z						cellular_component											owl:Class	
GO:0036117	biolink:NamedThing	hyaluranon cable	A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.	got7fsn_ti	HA cable						bf	2012-02-16T10:53:37Z						cellular_component											owl:Class	
GO:0009548	biolink:NamedThing	plasmodesmatal plasma membrane	The portion of the plasma membrane surrounding a plasmodesma.	got7fsn_ti														cellular_component											owl:Class	
GO:0021612	biolink:NamedThing	facial nerve structural organization	The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	got7fsn_ti	CN VII structural organization|facial nerve structural organisation													biological_process											owl:Class	
GO:0021610	biolink:NamedThing	facial nerve morphogenesis	The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	got7fsn_ti	CN VII morphogenesis													biological_process											owl:Class	
GO:0007080	biolink:NamedThing	mitotic metaphase plate congression	The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis.	got7fsn_ti														biological_process											owl:Class	
GO:0031505	biolink:NamedThing	fungal-type cell wall organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.	got7fsn_ti	chitin- and beta-glucan-containing cell wall organization and biogenesis|fungal-type cell wall organization and biogenesis|chitin-containing cell wall organization and biogenesis|beta-glucan-containing cell wall organization and biogenesis|chitin- and beta-glucan-containing cell wall organisation													biological_process											owl:Class	
GO:0009329	biolink:NamedThing	acetate CoA-transferase complex	A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA.	got7fsn_ti														cellular_component											owl:Class	
GO:0005880	biolink:NamedThing	nuclear microtubule	Any microtubule in the nucleus of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0030077	biolink:NamedThing	plasma membrane light-harvesting complex	A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species.	got7fsn_ti														cellular_component											owl:Class	
GO:2001235	biolink:NamedThing	positive regulation of apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.	got7fsn_ti	positive regulation of apoptotic signalling pathway						pr	2011-11-24T01:20:58Z						biological_process											owl:Class	
GO:0051331	biolink:NamedThing	meiotic G2 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.	got7fsn_ti	G2 phase of meiotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0030717	biolink:NamedThing	oocyte karyosome formation	The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.	got7fsn_ti														biological_process											owl:Class	
GO:1901028	biolink:NamedThing	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.	got7fsn_ti	regulation of MOMP|regulation of mitochondrial outer membrane permeabilization						pr	2012-06-20T09:19:16Z						biological_process											owl:Class	
GO:0034455	biolink:NamedThing	t-UTP complex	A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.	got7fsn_ti	Nan1p-containing subcomplex of 90S preribosome				Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.									cellular_component											owl:Class	
GO:0005730	biolink:NamedThing	nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.	got7fsn_ti												Wikipedia:Nucleolus|NIF_Subcellular:sao1820400233		cellular_component											owl:Class	
GO:0005654	biolink:NamedThing	nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.	got7fsn_ti												NIF_Subcellular:sao661522542|Wikipedia:Nucleoplasm		cellular_component											owl:Class	
GO:0039664	biolink:NamedThing	lysis of host organelle involved in viral entry into host cell	The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm.	got7fsn_ti	viral membrane-lytic protein|viral entry into host cell via endosome membrane lysis|viral penetration via lysis of host organellar membrane|viral entry into host cell via lysis of host organelle membrane						bf	2013-08-29T11:30:18Z				VZ:984		biological_process											owl:Class	
GO:0010097	biolink:NamedThing	specification of stamen identity	The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0048455	biolink:NamedThing	stamen formation	The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti											GO:0048427			biological_process											owl:Class	
GO:0005701	biolink:NamedThing	polytene chromosome chromocenter	A region at which the centric regions of polytene chromosomes are joined together.	got7fsn_ti	polytene chromosome chromocentre													cellular_component											owl:Class	
GO:0045266	biolink:NamedThing	plasma membrane proton-transporting ATP synthase, stator stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. Examples of this component are found in Bacterial species.	got7fsn_ti	hydrogen-transporting ATP synthase, stator stalk|proton-transporting ATP synthase, stator stalk													cellular_component											owl:Class	
GO:0045264	biolink:NamedThing	plasma membrane proton-transporting ATP synthase complex, coupling factor F(o)	All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins.	got7fsn_ti	proton-transporting ATP synthase complex, coupling factor F(o)|proton-transporting ATP synthase complex, coupling factor F(0)|hydrogen-transporting ATP synthase, F0 sector													cellular_component											owl:Class	
GO:0000748	biolink:NamedThing	conjugation with mutual genetic exchange	A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange.	got7fsn_ti	conjugation without cellular fusion													biological_process											owl:Class	
NCBITaxon:5878	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006948	biolink:NamedThing	induction by virus of host cell-cell fusion	The process of syncytia-forming cell-cell fusion, caused by a virus.	got7fsn_ti	viral-induced host cell-cell fusion|viral-induced cell-cell fusion|induction by virus of cell-cell fusion in host|viral-induced membrane fusion				Where syncytium formation results in the spread of virus in the host, also consider annotating to the term 'spread of virus in multicellular host ; GO:0046739'.									biological_process											owl:Class	
GO:1903073	biolink:NamedThing	negative regulation of death-inducing signaling complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly.	got7fsn_ti	negative regulation of DISC assembly|downregulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|downregulation of DD-mediated complex assembly|inhibition of DD-mediated complex assembly|down-regulation of DD-mediated complex assembly|downregulation of DISC formation|down regulation of death-inducing signalling complex assembly|inhibition of DISC formation|down regulation of DISC assembly|down-regulation of DISC assembly|negative regulation of death domain-mediated complex assembly|down-regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down regulation of DD-mediated complex assembly|inhibition of death-inducing signaling complex formation|negative regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down regulation of death-inducing signaling complex assembly|inhibition of death-inducing signalling complex assembly|down regulation of death-inducing signaling complex formation|downregulation of death-inducing signalling complex assembly|down-regulation of death-inducing signaling complex formation|negative regulation of DISC formation|inhibition of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down-regulation of death-inducing signalling complex assembly|downregulation of death-inducing signaling complex assembly|down regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down regulation of death domain-mediated complex assembly|inhibition of death-inducing signaling complex assembly|down regulation of DISC formation|down-regulation of death domain-mediated complex assembly|negative regulation of death-inducing signaling complex formation|inhibition of DISC assembly|down-regulation of death-inducing signaling complex assembly|downregulation of death domain-mediated complex assembly|down-regulation of DISC formation|downregulation of death-inducing signaling complex formation|downregulation of DISC assembly|inhibition of death domain-mediated complex assembly|negative regulation of death-inducing signalling complex assembly|negative regulation of DD-mediated complex assembly						bf	2014-05-29T09:33:20Z						biological_process											owl:Class	
GO:0018990	biolink:NamedThing	ecdysis, chitin-based cuticle	The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0015109	biolink:NamedThing	chromate transmembrane transporter activity	Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3.	got7fsn_ti												RHEA:32819		molecular_function											owl:Class	
GO:0015703	biolink:NamedThing	chromate transport	The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0060854	biolink:NamedThing	branching involved in lymph vessel morphogenesis	The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.	got7fsn_ti	patterning of lymph vessels						dph	2009-08-12T12:00:48Z						biological_process											owl:Class	
GO:0045143	biolink:NamedThing	homologous chromosome segregation	The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.	got7fsn_ti	meiosis I, chromosome segregation										GO:0007061			biological_process											owl:Class	
GO:0042501	biolink:NamedThing	serine phosphorylation of STAT protein	The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	got7fsn_ti	serine phosphorylation of STAT3 protein										GO:0033136			biological_process											owl:Class	
GO:0046425	biolink:NamedThing	regulation of receptor signaling pathway via JAK-STAT	Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT.	got7fsn_ti	STAT protein import into nucleus|regulation of STAT protein nuclear translocation|regulation of STAT protein import into nucleus	https://github.com/geneontology/go-ontology/issues/13686									GO:2000364|GO:0007262			biological_process											owl:Class	
GO:0031671	biolink:NamedThing	primary cell septum biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.	got7fsn_ti														biological_process											owl:Class	
GO:0140278	biolink:NamedThing	mitotic division septum assembly	The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.	got7fsn_ti							pg	2018-10-08T09:46:11Z						biological_process											owl:Class	
GO:0042584	biolink:NamedThing	chromaffin granule membrane	The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.	got7fsn_ti														cellular_component											owl:Class	
GO:0042583	biolink:NamedThing	chromaffin granule	Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.	got7fsn_ti														cellular_component											owl:Class	
GO:1900133	biolink:NamedThing	regulation of renin secretion into blood stream	Any process that modulates the frequency, rate or extent of renin secretion into blood stream.	got7fsn_ti	regulation of renin release into blood stream						rph	2012-02-27T10:32:01Z						biological_process											owl:Class	
GO:0097224	biolink:NamedThing	sperm connecting piece	The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum.	got7fsn_ti							pr	2012-01-25T01:21:02Z						cellular_component											owl:Class	
CL:0000019	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004001	biolink:NamedThing	adenosine kinase activity	Catalysis of the reaction: ATP + adenosine = ADP + AMP.	got7fsn_ti	adenosine kinase (phosphorylating)|adenosine 5-phosphotransferase activity|ATP:adenosine 5'-phosphotransferase activity											EC:2.7.1.20|RHEA:20824|Reactome:R-HSA-109624|MetaCyc:ADENOSINE-KINASE-RXN		molecular_function											owl:Class	
GO:0007132	biolink:NamedThing	meiotic metaphase I	The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0032870	biolink:NamedThing	cellular response to hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0015551	biolink:NamedThing	3-hydroxyphenyl propanoate transmembrane transporter activity	Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other.	got7fsn_ti	3-hydroxyphenyl propionate transmembrane transporter activity													molecular_function											owl:Class	
GO:0015731	biolink:NamedThing	3-hydroxyphenyl propanoate transport	The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	3-hydroxyphenyl propionate transport													biological_process											owl:Class	
GO:0048850	biolink:NamedThing	hypophysis morphogenesis	The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.	got7fsn_ti	pituitary gland morphogenesis													biological_process											owl:Class	
GO:0070926	biolink:NamedThing	regulation of ATP:ADP antiporter activity	Any process that modulates the activity of an ATP:ADP antiporter.	got7fsn_ti							mah	2009-09-16T02:56:35Z						biological_process											owl:Class	
GO:0015931	biolink:NamedThing	nucleobase-containing compound transport	The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	nucleobase, nucleoside, nucleotide and nucleic acid transport													biological_process											owl:Class	
GO:0043198	biolink:NamedThing	dendritic shaft	Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.	got7fsn_ti	trunk											NIF_Subcellular:sao2034472720		cellular_component											owl:Class	
GO:0070565	biolink:NamedThing	telomere-telomerase complex	A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome.	got7fsn_ti					Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome.		mah	2009-04-14T03:07:50Z						cellular_component											owl:Class	
GO:0000781	biolink:NamedThing	chromosome, telomeric region	The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres).	got7fsn_ti	nuclear chromosome, telomere|telomere|nuclear chromosome, telomeric region				Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex.						GO:0000784	SO:0000624		cellular_component											owl:Class	
GO:0009901	biolink:NamedThing	anther dehiscence	The dehiscence of an anther to release the pollen grains contained within it.	got7fsn_ti														biological_process											owl:Class	
GO:0007595	biolink:NamedThing	lactation	The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.	got7fsn_ti	milk secretion											Wikipedia:Lactation		biological_process											owl:Class	
GO:0035014	biolink:NamedThing	phosphatidylinositol 3-kinase regulator activity	Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.	got7fsn_ti	PI3K regulator activity|phosphoinositide 3-kinase regulator activity				See also the molecular function term 'phosphoinositide 3-kinase activity ; GO:0035004'.									molecular_function											owl:Class	
GO:1901721	biolink:NamedThing	positive regulation of NMS complex assembly	Any process that activates or increases the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.	got7fsn_ti	upregulation of NMS complex association involved in chromosome segregation|upregulation of NMS complex interaction involved in chromosome segregation|positive regulation of NMS complex assembly involved in kinetochore assembly|up regulation of KMN complex interaction involved in chromosome segregation|up-regulation of NMS complex interaction involved in chromosome segregation|up-regulation of NMS complex association involved in chromosome segregation|positive regulation of KMN network assembly involved in chromosome segregation|positive regulation of KMN complex interaction involved in chromosome segregation|upregulation of KMN complex interaction involved in chromosome segregation|up-regulation of KMN complex interaction involved in chromosome segregation|activation of KMN complex assembly involved in chromosome segregation|activation of NMS complex association involved in chromosome segregation|up regulation of KMN network assembly involved in chromosome segregation|up-regulation of KMN network assembly involved in chromosome segregation|activation of NMS complex interaction involved in chromosome segregation|upregulation of KMN network assembly involved in chromosome segregation|up regulation of NMS complex association involved in chromosome segregation|activation of KMN network assembly involved in chromosome segregation|positive regulation of NMS complex association involved in chromosome segregation|up regulation of NMS complex interaction involved in chromosome segregation						jl	2012-12-20T11:44:26Z						biological_process											owl:Class	
GO:0051382	biolink:NamedThing	kinetochore assembly	The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	got7fsn_ti	centromere/kinetochore complex maturation|kinetochore formation|centromere and kinetochore complex maturation|chromosome-kinetochore attachment										GO:0000069			biological_process											owl:Class	
GO:0003023	biolink:NamedThing	baroreceptor detection of increased arterial stretch	The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0009190	biolink:NamedThing	cyclic nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.	got7fsn_ti	cyclic nucleotide biosynthesis|cyclic nucleotide anabolism|cyclic nucleotide formation|cyclic nucleotide synthesis													biological_process											owl:Class	
GO:0044084	biolink:NamedThing	host cell membrane pore complex	Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins.	got7fsn_ti	pore complex in host cell membrane													cellular_component											owl:Class	
GO:0007534	biolink:NamedThing	gene conversion at mating-type locus	The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged.	got7fsn_ti	gene conversion at mating-type locus, DNA double-strand break formation|gene conversion at mating-type locus, DNA double-strand break processing|gene conversion at mating-type locus, termination of copy-synthesis|strand invasion involved in gene conversion at mating-type locus|heteroduplex formation involved in gene conversion at mating-type locus|gene conversion at mating-type locus, DNA repair synthesis	https://github.com/geneontology/go-ontology/issues/19999									GO:0031292|GO:0000734|GO:0010708|GO:0061500|GO:0000728|GO:0034636			biological_process											owl:Class	
GO:0030491	biolink:NamedThing	heteroduplex formation	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0010466	biolink:NamedThing	negative regulation of peptidase activity	Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0021987	biolink:NamedThing	cerebral cortex development	The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.	got7fsn_ti	corticogenesis|neocortex development													biological_process											owl:Class	
GO:0004951	biolink:NamedThing	cholecystokinin receptor activity	Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone.	got7fsn_ti	CCK receptor activity													molecular_function											owl:Class	
GO:0038188	biolink:NamedThing	cholecystokinin signaling pathway	The series of molecular signals generated as a consequence of cholecystokinin binding to a receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CCK signaling|cholecystokinin receptor signaling pathway						bf	2013-07-01T13:05:46Z				Wikipedia:Cholecystokinin		biological_process											owl:Class	
GO:0061773	biolink:NamedThing	eNoSc complex	A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation.	got7fsn_ti	energy dependent nucleolar silencing complex						dph	2016-07-09T10:12:30Z						cellular_component											owl:Class	
GO:0031492	biolink:NamedThing	nucleosomal DNA binding	Binding to the DNA portion of a nucleosome.	got7fsn_ti														molecular_function											owl:Class	
GO:0010793	biolink:NamedThing	regulation of mRNA export from nucleus	Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.	got7fsn_ti														biological_process											owl:Class	
GO:0021831	biolink:NamedThing	embryonic olfactory bulb interneuron precursor migration	The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb.	got7fsn_ti														biological_process											owl:Class	
GO:0021891	biolink:NamedThing	olfactory bulb interneuron development	The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0042692	biolink:NamedThing	muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.	got7fsn_ti	myogenesis													biological_process											owl:Class	
GO:0000965	biolink:NamedThing	mitochondrial RNA 3'-end processing	Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.	got7fsn_ti	mitochondrial RNA 3' end processing													biological_process											owl:Class	
GO:0001556	biolink:NamedThing	oocyte maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.	got7fsn_ti												Wikipedia:Oocyte_maturation		biological_process											owl:Class	
GO:0048599	biolink:NamedThing	oocyte development	The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0030965	biolink:NamedThing	plasma membrane electron transport, NADH to quinone	The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase.	got7fsn_ti														biological_process											owl:Class	
GO:0042774	biolink:NamedThing	plasma membrane ATP synthesis coupled electron transport	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0021978	biolink:NamedThing	telencephalon regionalization	The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.	got7fsn_ti														biological_process											owl:Class	
GO:0021871	biolink:NamedThing	forebrain regionalization	The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops.	got7fsn_ti														biological_process											owl:Class	
GO:0021691	biolink:NamedThing	cerebellar Purkinje cell layer maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	got7fsn_ti														biological_process											owl:Class	
GO:0004057	biolink:NamedThing	arginyltransferase activity	Catalysis of the reaction: L-arginyl-tRNA + protein = tRNA + L-arginyl-protein.	got7fsn_ti	arginyl-tRNA-protein transferase activity|arginyl-transfer ribonucleate-protein transferase activity|L-arginyl-tRNA:protein arginyltransferase activity|arginine transferase activity|arginyl-tRNA protein transferase activity|arginyl-transfer ribonucleate-protein aminoacyltransferase activity|arginyl-tRNA--protein transferase activity										GO:0042172	RHEA:10208|MetaCyc:ARGINYLTRANSFERASE-RXN|EC:2.3.2.8		molecular_function											owl:Class	
GO:1990230	biolink:NamedThing	iron-sulfur cluster transfer complex	A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor).	got7fsn_ti	Fe-S cluster transfer complex|IscA complex|SufA complex|SufA dimer						bhm	2013-11-12T09:17:40Z						cellular_component											owl:Class	
GO:0086033	biolink:NamedThing	G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate.	got7fsn_ti	muscarinic acetylcholine receptor signaling pathway involved in negative regulation of heart rate|M2 receptor signalling pathway involved in negative regulation of heart rate|G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate						tb	2011-11-11T03:11:58Z						biological_process											owl:Class	
GO:0003063	biolink:NamedThing	negative regulation of heart rate by acetylcholine	The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.	got7fsn_ti	negative regulation of heart contraction rate by acetylcholine													biological_process											owl:Class	
GO:0032060	biolink:NamedThing	bleb assembly	The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.	got7fsn_ti	plasma membrane blebbing|membrane blebbing|blebbing|cell blebbing|plasma membrane bleb assembly													biological_process											owl:Class	
GO:0020026	biolink:NamedThing	merozoite dense granule	Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell.	got7fsn_ti	dense body													cellular_component											owl:Class	
NCBITaxon:5794	biolink:NamedThing			got7fsn_ti																									owl:Class	
NCBITaxon:7742	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048735	biolink:NamedThing	haltere morphogenesis	The process in which the anatomical structures of a haltere are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0007482	biolink:NamedThing	haltere development	The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.	got7fsn_ti														biological_process											owl:Class	
GO:0042716	biolink:NamedThing	plasma membrane-derived chromatophore	A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria.	got7fsn_ti	chromatophore vesicle				Note that this structure is distinct from the chromoplast of plants, which is also sometimes called a chromatophore; it also should not be confused with the specialized pigment-producing cells known as chromatophores, found in fish and amphibian skin.									cellular_component											owl:Class	
GO:0042693	biolink:NamedThing	muscle cell fate commitment	The process in which the cellular identity of muscle cells is acquired and determined.	got7fsn_ti														biological_process											owl:Class	
GO:0009546	biolink:NamedThing	plasmodesmatal cytoplasmic sleeve	The space between the plasma membrane and the desmotubule of a plasmodesma.	got7fsn_ti	plasmodesmatal cytoplasmic annulus													cellular_component											owl:Class	
GO:0035865	biolink:NamedThing	cellular response to potassium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.	got7fsn_ti	cellular response to K+ ion|cellular response to potassium						bf	2011-05-25T02:59:11Z						biological_process											owl:Class	
GO:1990613	biolink:NamedThing	mitochondrial membrane fusion	The joining of two lipid bilayers that surround the mitochondria.	got7fsn_ti							vw	2015-01-21T06:58:18Z						biological_process											owl:Class	
GO:0061701	biolink:NamedThing	bacterial outer membrane vesicle	A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes.	got7fsn_ti							dph	2015-05-07T13:53:47Z						cellular_component											owl:Class	
GO:0090552	biolink:NamedThing	unicellular trichome apex	A cell projection part that is the apical most portion of a unicellular trichome.	got7fsn_ti							tb	2013-04-25T11:56:56Z						cellular_component											owl:Class	
GO:0086058	biolink:NamedThing	voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti							dph	2011-11-17T12:35:02Z						molecular_function											owl:Class	
GO:0086047	biolink:NamedThing	membrane depolarization during Purkinje myocyte cell action potential	The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti							dph	2011-11-16T10:54:47Z						biological_process											owl:Class	
GO:0020011	biolink:NamedThing	apicoplast	The plastid organelle found in apicomplexans.	got7fsn_ti												Wikipedia:Apicoplast		cellular_component											owl:Class	
GO:0061228	biolink:NamedThing	mesonephric nephron morphogenesis	The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.	got7fsn_ti							dph	2010-08-19T02:26:24Z						biological_process											owl:Class	
GO:0044857	biolink:NamedThing	plasma membrane raft organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.	got7fsn_ti							jl	2014-07-23T16:20:07Z						biological_process											owl:Class	
GO:0030997	biolink:NamedThing	regulation of centriole-centriole cohesion	Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker.	got7fsn_ti														biological_process											owl:Class	
GO:0007098	biolink:NamedThing	centrosome cycle	The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.	got7fsn_ti	centrosome organization and biogenesis|centrosome organisation|centrosome organization										GO:0051297			biological_process											owl:Class	
GO:0071023	biolink:NamedThing	trans spliceosomal complex	A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.	got7fsn_ti							mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0045170	biolink:NamedThing	spectrosome	A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome.	got7fsn_ti														cellular_component											owl:Class	
GO:0060171	biolink:NamedThing	stereocilium membrane	The portion of the plasma membrane surrounding a stereocilium.	got7fsn_ti														cellular_component											owl:Class	
GO:0048942	biolink:NamedThing	posterior lateral line nerve glial cell morphogenesis involved in differentiation	The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0022405	biolink:NamedThing	hair cycle process	A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.	got7fsn_ti														biological_process											owl:Class	
GO:0042633	biolink:NamedThing	hair cycle	The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.	got7fsn_ti														biological_process											owl:Class	
GO:0015148	biolink:NamedThing	D-xylose transmembrane transporter activity	Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.	got7fsn_ti														molecular_function											owl:Class	
GO:0015753	biolink:NamedThing	D-xylose transmembrane transport	The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.	got7fsn_ti	D-xylose transport													biological_process											owl:Class	
GO:0031069	biolink:NamedThing	hair follicle morphogenesis	The process in which the anatomical structures of the hair follicle are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0048730	biolink:NamedThing	epidermis morphogenesis	The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.	got7fsn_ti	hypodermis morphogenesis													biological_process											owl:Class	
GO:0060165	biolink:NamedThing	regulation of timing of subpallium neuron differentiation	The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon.	got7fsn_ti														biological_process											owl:Class	
GO:1904438	biolink:NamedThing	regulation of iron ion import across plasma membrane	Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane.	got7fsn_ti	regulation of ferrous iron import across plasma membrane|regulation of ferrous ion import into cell|regulation of ferrous iron import into cell						rl	2015-03-04T14:37:36Z			GO:1903989			biological_process											owl:Class	
GO:0062079	biolink:NamedThing	ATG2-ATG18 complex	A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae.	got7fsn_ti							dph	2018-10-12T13:47:25Z						cellular_component											owl:Class	
GO:0006821	biolink:NamedThing	chloride transport	The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0043108	biolink:NamedThing	pilus retraction	The process of withdrawing a pilus back into a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0042884	biolink:NamedThing	microcin transport	The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0034662	biolink:NamedThing	CFTR-NHERF-ezrin complex	A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0042662	biolink:NamedThing	negative regulation of mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.	got7fsn_ti	inhibition of mesodermal cell fate specification|suppression of mesodermal cell fate|downregulation of mesodermal cell fate specification|down-regulation of mesodermal cell fate specification|down regulation of mesodermal cell fate specification													biological_process											owl:Class	
GO:0043592	biolink:NamedThing	exosporium	The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid.	got7fsn_ti	exospore|perispore|epispore													cellular_component											owl:Class	
GO:1990060	biolink:NamedThing	maltose transport complex	Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK.	got7fsn_ti	maltose ABC transporter complex|maltose ATP-binding cassette transporter complex						jl	2013-03-13T13:52:48Z						cellular_component											owl:Class	
GO:0042790	biolink:NamedThing	nucleolar large rRNA transcription by RNA polymerase I	The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I.	got7fsn_ti	transcription of nucleolar large rRNA by RNA polymerase I|transcription of nuclear large rRNA transcript from RNA polymerase I promoter|transcription of nuclear rRNA large Pol I transcript	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0070380	biolink:NamedThing	high mobility group box 1 receptor activity	Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	HMGB1 receptor activity													molecular_function											owl:Class	
GO:1900262	biolink:NamedThing	regulation of DNA-directed DNA polymerase activity	Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity.	got7fsn_ti	regulation of lambda DNA polymerase activity|regulation of DNA duplicase activity|regulation of sequenase|regulation of kappa DNA polymerase activity|regulation of DNA nucleotidyltransferase (DNA-directed) activity|regulation of DNA polymerase II|regulation of DNA replicase activity|regulation of sigma DNA polymerase activity|regulation of beta DNA polymerase activity|regulation of Klenow fragment|regulation of eta DNA polymerase activity|regulation of zeta DNA polymerase activity|regulation of DNA-dependent DNA polymerase activity|regulation of delta DNA polymerase activity|regulation of theta DNA polymerase activity|regulation of DNA polymerase gamma|regulation of DNA polymerase alpha|regulation of Taq DNA polymerase|regulation of deoxyribonucleic duplicase activity|regulation of deoxyribonucleic polymerase I|regulation of DNA polymerase V activity|regulation of mu DNA polymerase activity|regulation of deoxyribonucleic acid duplicase activity|regulation of iota DNA polymerase activity|regulation of nu DNA polymerase activity|regulation of duplicase|regulation of epsilon DNA polymerase activity|regulation of DNA polymerase beta|regulation of Taq Pol I|regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|regulation of alpha DNA polymerase activity|regulation of DNA polymerase III|regulation of gamma DNA-directed DNA polymerase activity|regulation of Tca DNA polymerase|regulation of DNA polymerase I						tb	2012-04-03T11:07:08Z						biological_process											owl:Class	
GO:0046628	biolink:NamedThing	positive regulation of insulin receptor signaling pathway	Any process that increases the frequency, rate or extent of insulin receptor signaling.	got7fsn_ti	up-regulation of insulin receptor signaling pathway|stimulation of insulin receptor signaling pathway|activation of insulin receptor signaling pathway|positive regulation of insulin receptor signalling pathway|up regulation of insulin receptor signaling pathway|upregulation of insulin receptor signaling pathway													biological_process											owl:Class	
GO:0030428	biolink:NamedThing	cell septum	A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.	got7fsn_ti	septum|cross wall													cellular_component											owl:Class	
GO:1990100	biolink:NamedThing	DnaB-DnaC complex	A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC).	got7fsn_ti	helicase-loading complex|DnaB6-DnaC3 complex|DnaB6-DnaC6 complex				DnaB and DnaC may be present in different ratios in different forms of the DnaB-DnaC complex, including a DnaB6-DnaC3 complex active at the oriC, and a DnaB6-DnaC6 complex.		bhm	2013-05-14T12:02:22Z						cellular_component											owl:Class	
GO:0034257	biolink:NamedThing	nicotinamide riboside transmembrane transporter activity	Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.	got7fsn_ti												RHEA:33163		molecular_function											owl:Class	
GO:0034258	biolink:NamedThing	nicotinamide riboside transport	The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1904886	biolink:NamedThing	beta-catenin destruction complex disassembly	The disaggregation of a beta-catenin destruction complex into its constituent components.	got7fsn_ti	23S APC complex disassembly|dissociation of beta-catenin degradation complex|BDC disassembly|beta-catenin degradation complex disassembly|APC-Axin-1-beta-catenin complex disassembly|Axin-APC-beta-catenin-GSK3B complex disassembly						bf	2016-01-05T11:41:02Z						biological_process											owl:Class	
GO:0060070	biolink:NamedThing	canonical Wnt signaling pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	got7fsn_ti	Wnt receptor signaling pathway through beta-catenin|canonical Wnt receptor signaling pathway|Wnt receptor signaling pathway via beta-catenin|canonical Wnt-activated signaling pathway|Wnt receptor signalling pathway through beta-catenin|frizzled-1 receptor signaling pathway													biological_process											owl:Class	
GO:0001986	biolink:NamedThing	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.	got7fsn_ti	decreased strength of cardiac contraction during baroreceptor response to increased blood pressure|decreased force of heart contraction during baroreceptor response to increased systemic arterial blood pressure													biological_process											owl:Class	
GO:0048357	biolink:NamedThing	pedicel mucilage biosynthetic process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem.	got7fsn_ti	pedicel mucilage formation|pedicel mucilage anabolism|pedicel mucilage synthesis|pedicel mucilage biosynthesis													biological_process											owl:Class	
GO:0048362	biolink:NamedThing	pedicel mucilage metabolic process	The chemical reactions and pathways involving mucilage that occur in the flower stem.	got7fsn_ti	pedicel mucilage metabolism													biological_process											owl:Class	
GO:0015633	biolink:NamedThing	ABC-type zinc transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in).	got7fsn_ti	zinc transporting ATPase activity|ATP-dependent zinc transmembrane transporter activity|zinc-transporting ATPase activity|ATPase-coupled zinc transmembrane transporter activity|zinc porter activity											RHEA:29795|EC:7.2.2.20		molecular_function											owl:Class	
GO:0071577	biolink:NamedThing	zinc ion transmembrane transport	A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	zinc transmembrane transport|zinc II ion transmembrane transport|zinc ion membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-01-28T02:17:12Z						biological_process											owl:Class	
GO:0015230	biolink:NamedThing	FAD transmembrane transporter activity	Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.	got7fsn_ti	flavin adenine dinucleotide transmembrane transporter activity|flavin-adenine dinucleotide transmembrane transporter activity|FAD carrier activity|FAD transporter activity|flavin adenine dinucleotide carrier activity|flavin-adenine dinucleotide carrier activity										GO:0005472			molecular_function											owl:Class	
GO:0035350	biolink:NamedThing	FAD transmembrane transport	The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.	got7fsn_ti	FAD membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:45:11Z						biological_process											owl:Class	
GO:0045284	biolink:NamedThing	plasma membrane fumarate reductase complex	A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species.	got7fsn_ti	fumarate reductase complex				See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'.									cellular_component											owl:Class	
GO:0045274	biolink:NamedThing	plasma membrane respiratory chain complex II	A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. Examples of this component are found in bacterial species.	got7fsn_ti	respiratory chain complex II													cellular_component											owl:Class	
GO:0050322	biolink:NamedThing	taurine-2-oxoglutarate transaminase activity	Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.	got7fsn_ti	taurine aminotransferase activity|taurine--alpha-ketoglutarate aminotransferase activity|taurine transaminase activity|taurine--glutamate transaminase activity|taurine:2-oxoglutarate aminotransferase activity											EC:2.6.1.55|MetaCyc:RXN-2301|RHEA:16353		molecular_function											owl:Class	
GO:0070743	biolink:NamedThing	interleukin-23 complex	A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.	got7fsn_ti	p40|IL-23 complex|IL23A|p19|IL12B				Note that this heterodimeric cytokine utilizes the same beta subunit as IL-12.		mah	2009-06-23T01:06:02Z						cellular_component											owl:Class	
GO:0009908	biolink:NamedThing	flower development	The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.	got7fsn_ti											GO:0048409			biological_process											owl:Class	
GO:0061458	biolink:NamedThing	reproductive system development	The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.	got7fsn_ti							dph	2012-08-22T17:47:53Z						biological_process											owl:Class	
GO:0060317	biolink:NamedThing	cardiac epithelial to mesenchymal transition	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti	heart epithelial to mesenchymal transition													biological_process											owl:Class	
GO:0031504	biolink:NamedThing	peptidoglycan-based cell wall organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall.	got7fsn_ti	peptidoglycan-based cell wall organisation|peptidoglycan-based cell wall organization and biogenesis													biological_process											owl:Class	
GO:0035077	biolink:NamedThing	ecdysone-mediated polytene chromosome puffing	The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.	got7fsn_ti														biological_process											owl:Class	
GO:0071390	biolink:NamedThing	cellular response to ecdysone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.	got7fsn_ti							mah	2009-12-11T04:03:57Z						biological_process											owl:Class	
GO:0098751	biolink:NamedThing	bone cell development	The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti					Not to be used for manual annotation.  Please choose a more specific cell development term or if not possible, bone or bone tissue development.									biological_process											owl:Class	
GO:0060348	biolink:NamedThing	bone development	The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.	got7fsn_ti														biological_process											owl:Class	
GO:0036484	biolink:NamedThing	trunk neural crest cell migration	The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo.	got7fsn_ti	trunk NCC migration						bf	2014-08-26T15:27:44Z						biological_process											owl:Class	
GO:0035290	biolink:NamedThing	trunk segmentation	Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.	got7fsn_ti														biological_process											owl:Class	
GO:0120293	biolink:NamedThing	dynein axonemal particle	An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm.	got7fsn_ti	DynAP	https://github.com/geneontology/go-ontology/issues/20687					krc	2021-01-19T01:47:17Z						cellular_component											owl:Class	
GO:0031092	biolink:NamedThing	platelet alpha granule membrane	The lipid bilayer surrounding the platelet alpha granule.	got7fsn_ti	platelet alpha-granule membrane													cellular_component											owl:Class	
GO:0034342	biolink:NamedThing	response to type III interferon	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	response to interferon-lambda|response to type III IFN													biological_process											owl:Class	
GO:1901726	biolink:NamedThing	negative regulation of histone deacetylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity.	got7fsn_ti	down-regulation of histone deacetylase activity|downregulation of histone deacetylase activity|inhibition of histone deacetylase activity|down regulation of histone deacetylase activity						rl	2013-01-07T09:14:17Z						biological_process											owl:Class	
GO:0043625	biolink:NamedThing	delta DNA polymerase complex	A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.	got7fsn_ti	delta-DNA polymerase complex										GO:0005659			cellular_component											owl:Class	
GO:0071365	biolink:NamedThing	cellular response to auxin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.	got7fsn_ti							mah	2009-12-11T03:10:22Z						biological_process											owl:Class	
GO:0017128	biolink:NamedThing	phospholipid scramblase activity	Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.	got7fsn_ti					Nomenclature note. Scramblases are ATP-independent, non-selective, translocases inducing non-specific transbilayer movements across the membrane. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases).									molecular_function											owl:Class	
GO:0017121	biolink:NamedThing	plasma membrane phospholipid scrambling	The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).	got7fsn_ti	PL scrambling|phospholipid scrambling				Note that this term describes the trans-bilayer motion of a population of phospholipid molecules, and should not be confused with 'phospholipid translocation ; GO:0045332'.									biological_process											owl:Class	
GO:0070153	biolink:NamedThing	mitochondrial leucyl-tRNA aminoacylation	The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0090615	biolink:NamedThing	mitochondrial mRNA processing	Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.	got7fsn_ti							tb	2014-10-24T12:43:27Z						biological_process											owl:Class	
GO:0007083	biolink:NamedThing	mitotic chromosome decondensation	The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells.	got7fsn_ti														biological_process											owl:Class	
GO:0000070	biolink:NamedThing	mitotic sister chromatid segregation	The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.	got7fsn_ti	mitotic sister-chromatid adhesion release|mitotic chromosome segregation										GO:0016359			biological_process											owl:Class	
GO:0061838	biolink:NamedThing	CENP-T-W-S-X complex	A histone-variant containing protein complex which forms a centromere specific nucleosomal structure, involved in centromeric chromatin organization.	got7fsn_ti														cellular_component											owl:Class	
GO:0000775	biolink:NamedThing	chromosome, centromeric region	The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.	got7fsn_ti	chromosome, pericentric region|centromere|centromere complex|chromosome, centric region				Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'.						GO:0097521	SO:0000577		cellular_component											owl:Class	
GO:0009654	biolink:NamedThing	photosystem II oxygen evolving complex	A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ).	got7fsn_ti	oxygen evolving complex|OEC (PSII) complex											Wikipedia:Oxygen_evolving_complex		cellular_component											owl:Class	
GO:0044512	biolink:NamedThing	envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism.	got7fsn_ti							jl	2012-02-26T10:20:19Z						biological_process											owl:Class	
GO:0044506	biolink:NamedThing	modulation of glucagon-like peptide receptor 1 activity in other organism	The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism.	got7fsn_ti	regulation of glucagon-like peptide receptor activity in other organism						jl	2012-02-23T04:29:14Z						biological_process											owl:Class	
GO:0048480	biolink:NamedThing	stigma development	The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky.	got7fsn_ti														biological_process											owl:Class	
GO:0003235	biolink:NamedThing	sinus venosus development	The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.	got7fsn_ti							dph	2009-10-13T11:12:34Z						biological_process											owl:Class	
GO:1990661	biolink:NamedThing	S100A8 complex	A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4).	got7fsn_ti	S100A8 homodimer				An example of this is S100A8 in human (UniProt symbol P27005) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T15:33:32Z						cellular_component											owl:Class	
GO:0000910	biolink:NamedThing	cytokinesis	The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.	got7fsn_ti	cell cycle cytokinesis|cytokinesis involved in cell cycle				Note that this term should not be used for direct annotation. When annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639.  Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other.						GO:0016288|GO:0007104|GO:0033205	Wikipedia:Cytokinesis		biological_process											owl:Class	
PR:000000001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005786	biolink:NamedThing	signal recognition particle, endoplasmic reticulum targeting	A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana.	got7fsn_ti	signal sequence receptor complex|SRP										GO:0005855	Wikipedia:Signal_recognition_particle		cellular_component											owl:Class	
GO:0097399	biolink:NamedThing	interleukin-32-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-32 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-32-mediated signaling pathway|interleukin-32-mediated signalling pathway|IL-32-mediated signalling pathway						pr	2012-10-23T13:27:22Z						biological_process											owl:Class	
GO:0036349	biolink:NamedThing	galactose-specific flocculation	The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other.	got7fsn_ti	cell-cell adhesion involved in galactose-specific flocculation						bf	2012-09-19T10:56:16Z			GO:0098611			biological_process											owl:Class	
GO:0005534	biolink:NamedThing	galactose binding	Binding to aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.	got7fsn_ti	galactose binding lectin													molecular_function											owl:Class	
GO:0052607	biolink:NamedThing	7-hydroxy-chlorophyllide a oxygenase activity	Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O.	got7fsn_ti	CAO activity|chlorophyll-b synthase activity|chlorophyll b synthetase activity|7-hydroxychlorophyllide-a oxygenase activity|7-hydroxychlorophyllide a:oxygen 7-oxidoreductase activity											KEGG_REACTION:R08204|MetaCyc:RXN-7677|RHEA:22136		molecular_function											owl:Class	
GO:0010277	biolink:NamedThing	chlorophyllide a oxygenase [overall] activity	Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.	got7fsn_ti	CAO activity|chlorophyll a oxygenation activity|chlorophyllide-a oxygenation activity|chlorophyll-b synthesis activity|chlorophyllide a:oxygen 7-oxidoreduction activity|chlorophyll b synthesis activity				This is a process composed of two reactions represented by the terms 'GO:0052606 : chlorophyllide a oxygenase activity' and 'GO:0052607 : 7-hydroxy-chlorophyllide a oxygenase activity'.						GO:0046407	EC:1.14.13.122|RHEA:30359		molecular_function											owl:Class	
GO:1901046	biolink:NamedThing	positive regulation of oviposition	Any process that activates or increases the frequency, rate or extent of oviposition.	got7fsn_ti	positive regulation of egg-laying|up regulation of oviposition|up-regulation of egg-laying|activation of egg laying|upregulation of oviposition|activation of egg-laying|positive regulation of egg laying|activation of oviposition|up-regulation of oviposition|up-regulation of egg laying|upregulation of egg laying|up regulation of egg laying|up regulation of egg-laying|upregulation of egg-laying						kmv	2012-06-27T06:20:20Z						biological_process											owl:Class	
GO:0004862	biolink:NamedThing	cAMP-dependent protein kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a cAMP-dependent protein kinase.	got7fsn_ti												Reactome:R-HSA-180073		molecular_function											owl:Class	
GO:0060415	biolink:NamedThing	muscle tissue morphogenesis	The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.	got7fsn_ti														biological_process											owl:Class	
GO:0048644	biolink:NamedThing	muscle organ morphogenesis	The process in which the anatomical structures of muscle are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:1990905	biolink:NamedThing	dinoflagellate peduncle	A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy).	got7fsn_ti					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2015-11-22T10:22:46Z						cellular_component											owl:Class	
GO:0043315	biolink:NamedThing	positive regulation of neutrophil degranulation	Any process that activates or increases the frequency, rate or extent of neutrophil degranulation.	got7fsn_ti	activation of neutrophil degranulation|upregulation of neutrophil degranulation|positive regulation of neutrophil granule exocytosis|stimulation of neutrophil degranulation|up-regulation of neutrophil degranulation|up regulation of neutrophil degranulation													biological_process											owl:Class	
GO:0005884	biolink:NamedThing	actin filament	A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.	got7fsn_ti	microfilament											FMA:63850|NIF_Subcellular:sao1588493326|Wikipedia:Actin		cellular_component											owl:Class	
GO:0061822	biolink:NamedThing	ciliary cap	An intracellular compartmentalized cilium structure found in insect spermatids which is bounded by a membrane derived from the invagination of the cell membrane that remains associated with the primary cilium as it is internalized. The ciliary cap is maintained at the end of the axoneme distal to the centriole and is separated from the cytosolic axoneme/cytoplasm by a putative transition zone, which may extend into the ciliary cap, and include a structure at the base of the ciliary cap termed the ring centriole.	got7fsn_ti	spermatid ciliary cap						dph	2017-01-14T14:14:11Z						cellular_component											owl:Class	
GO:0034510	biolink:NamedThing	centromere separation	The cell cycle process in which centromeres are physically detached from each other during chromosome separation.	got7fsn_ti														biological_process											owl:Class	
GO:0098813	biolink:NamedThing	nuclear chromosome segregation	The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.	got7fsn_ti														biological_process											owl:Class	
GO:0044638	biolink:NamedThing	envenomation resulting in positive regulation of complement activation, classical pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism.	got7fsn_ti							jl	2012-07-05T04:51:36Z						biological_process											owl:Class	
GO:0044628	biolink:NamedThing	positive regulation of complement activation, classical pathway in other organism	Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism.	got7fsn_ti							jl	2012-07-05T01:00:10Z						biological_process											owl:Class	
GO:0000966	biolink:NamedThing	RNA 5'-end processing	Any process involved in forming the mature 5' end of an RNA molecule.	got7fsn_ti	RNA 5' end processing													biological_process											owl:Class	
GO:0052884	biolink:NamedThing	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity	Catalysis of the reaction: H(2)O + all-trans-retinyl palmitate = 11-cis-retinol + H(+) + palmitate.	got7fsn_ti	retinol isomerase activity|all-trans-retinol isomerase:hydrolase activity|all-trans-retinyl-palmitate hydrolase activity|retinoid isomerohydrolase activity											RHEA:31775|Reactome:R-HSA-2453833|EC:3.1.1.64		molecular_function											owl:Class	
GO:0042572	biolink:NamedThing	retinol metabolic process	The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.	got7fsn_ti	vitamin A1 metabolic process|vitamin A1 alcohol metabolism|retinol metabolism|vitamin A1 metabolism|vitamin A1 alcohol metabolic process											Wikipedia:Retinol		biological_process											owl:Class	
GO:0000502	biolink:NamedThing	proteasome complex	A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.	got7fsn_ti	26S proteasome|proteasome													cellular_component											owl:Class	
GO:0015412	biolink:NamedThing	ABC-type molybdate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in).	got7fsn_ti	molybdate transmembrane-transporting ATPase activity|molybdate transporting ATPase activity|ATPase-coupled molybdate transmembrane transporter activity|molybdate ABC transporter|molybdate porter activity|molybdate-transporting ATPase activity											EC:7.3.2.5|MetaCyc:3.6.3.29-RXN|RHEA:22020		molecular_function											owl:Class	
GO:0015689	biolink:NamedThing	molybdate ion transport	The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0030297	biolink:NamedThing	transmembrane receptor protein tyrosine kinase activator activity	Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.	got7fsn_ti														molecular_function											owl:Class	
GO:0007171	biolink:NamedThing	activation of transmembrane receptor protein tyrosine kinase activity	Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.	got7fsn_ti	transmembrane receptor protein tyrosine kinase dimerization|transmembrane receptor protein tyrosine kinase activation													biological_process											owl:Class	
GO:0045124	biolink:NamedThing	regulation of bone resorption	Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).	got7fsn_ti														biological_process											owl:Class	
GO:0034519	biolink:NamedThing	cytoplasmic RNA cap binding complex	A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA.	got7fsn_ti														cellular_component											owl:Class	
GO:0042016	biolink:NamedThing	interleukin-20 receptor activity	Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-20 receptor activity|IL-20R													molecular_function											owl:Class	
GO:1990231	biolink:NamedThing	STING complex	A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides.  Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the  innate immune response.	got7fsn_ti	stimulator of interferon genes complex						bhm	2013-11-12T10:58:34Z						cellular_component											owl:Class	
GO:0061507	biolink:NamedThing	2',3'-cyclic GMP-AMP binding	Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.	got7fsn_ti	2',3'-cyclic GAMP binding|2',3' cyclic GAMP binding|2',5-3',5'-cyclic GMP-AMP binding|2',3'-cGAMP binding|cyclic-GMP-AMP binding|2',3' cGAMP binding|c[G(2',5')pA(3',5')p] binding	https://github.com/geneontology/go-ontology/issues/21980					dph	2013-01-24T15:38:27Z			GO:0098546			molecular_function											owl:Class	
GO:0061194	biolink:NamedThing	taste bud morphogenesis	The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.	got7fsn_ti							dph	2010-07-27T11:01:31Z						biological_process											owl:Class	
GO:0072589	biolink:NamedThing	box H/ACA scaRNP complex	A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs.	got7fsn_ti	nucleoplasmic box H/ACA RNP pseudouridylase complex						mah	2011-02-10T02:47:17Z						cellular_component											owl:Class	
GO:0021713	biolink:NamedThing	inferior olivary nucleus development	The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	got7fsn_ti	inferior olive development													biological_process											owl:Class	
GO:0051307	biolink:NamedThing	meiotic chromosome separation	The process in which chromosomes are physically detached from each other during meiosis.	got7fsn_ti	chromosome separation during meiosis|meiotic chromosome resolution													biological_process											owl:Class	
GO:0002812	biolink:NamedThing	biosynthetic process of antibacterial peptides active against Gram-negative bacteria	The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.	got7fsn_ti														biological_process											owl:Class	
GO:0050829	biolink:NamedThing	defense response to Gram-negative bacterium	Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.	got7fsn_ti	defence response to Gram-negative bacterium|Gram-negative antibacterial peptide activity|defence response to Gram-negative bacteria|defense response to Gram-negative bacteria													biological_process											owl:Class	
GO:0008198	biolink:NamedThing	ferrous iron binding	Binding to a ferrous iron ion, Fe(II).	got7fsn_ti														molecular_function											owl:Class	
GO:0050187	biolink:NamedThing	phosphoamidase activity	Catalysis of the reaction: N-phosphocreatine + H(2)O = creatine + phosphate.	got7fsn_ti	phosphamide hydrolase activity|creatine phosphatase activity											RHEA:12977|EC:3.9.1.1|KEGG_REACTION:R01882|MetaCyc:PHOSPHOAMIDASE-RXN		molecular_function											owl:Class	
GO:0033026	biolink:NamedThing	negative regulation of mast cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.	got7fsn_ti	down regulation of mast cell apoptosis|inhibition of mast cell apoptosis|negative regulation of mast cell apoptosis|down-regulation of mast cell apoptosis|downregulation of mast cell apoptosis													biological_process											owl:Class	
GO:0070145	biolink:NamedThing	mitochondrial asparaginyl-tRNA aminoacylation	The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0098970	biolink:NamedThing	postsynaptic neurotransmitter receptor diffusion trapping	The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization.	got7fsn_ti														biological_process											owl:Class	
GO:0099634	biolink:NamedThing	postsynaptic specialization membrane	The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.	got7fsn_ti														cellular_component											owl:Class	
GO:0061029	biolink:NamedThing	eyelid development in camera-type eye	The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.	got7fsn_ti							dph	2010-02-09T09:36:11Z						biological_process											owl:Class	
GO:0048527	biolink:NamedThing	lateral root development	The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.	got7fsn_ti														biological_process											owl:Class	
GO:1990047	biolink:NamedThing	spindle matrix	A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis.	got7fsn_ti							pr	2013-02-18T08:51:47Z						cellular_component											owl:Class	
GO:0001527	biolink:NamedThing	microfibril	Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins.	got7fsn_ti	fibrillin|extended fibrils													cellular_component											owl:Class	
NCBITaxon:4952	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042063	biolink:NamedThing	gliogenesis	The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.	got7fsn_ti	glial cell generation													biological_process											owl:Class	
GO:0000162	biolink:NamedThing	tryptophan biosynthetic process	The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.	got7fsn_ti	tryptophan anabolism|tryptophan formation|tryptophan synthesis|tryptophan biosynthesis|aromatic amino acid family biosynthetic process, anthranilate pathway										GO:0009096	MetaCyc:TRPSYN-PWY		biological_process											owl:Class	
GO:0051875	biolink:NamedThing	pigment granule localization	Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	pigment granule localisation													biological_process											owl:Class	
GO:0007417	biolink:NamedThing	central nervous system development	The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	got7fsn_ti	CNS development											Wikipedia:Neural_development		biological_process											owl:Class	
GO:0042025	biolink:NamedThing	host cell nucleus	A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti											GO:0033649			cellular_component											owl:Class	
GO:0030478	biolink:NamedThing	actin cap	Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae.	got7fsn_ti											GO:0000143			cellular_component											owl:Class	
GO:0060681	biolink:NamedThing	branch elongation involved in ureteric bud branching	The growth of a branch of the ureteric bud along its axis.	got7fsn_ti							dph	2009-06-02T02:52:55Z						biological_process											owl:Class	
GO:0060677	biolink:NamedThing	ureteric bud elongation	The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.	got7fsn_ti							dph	2009-06-02T02:13:29Z						biological_process											owl:Class	
GO:0071922	biolink:NamedThing	regulation of cohesin loading	Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.	got7fsn_ti	regulation of cohesin localisation to chromatin|regulation of cohesin association with chromatin|regulation of cohesin localization to chromatin						mah	2010-09-28T11:13:35Z						biological_process											owl:Class	
GO:0001845	biolink:NamedThing	phagolysosome assembly	The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome.	got7fsn_ti	late phagosome formation|late phagosome biosynthesis|phagolysosome formation													biological_process											owl:Class	
GO:0006909	biolink:NamedThing	phagocytosis	A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.	got7fsn_ti												Wikipedia:Phagocytosis		biological_process											owl:Class	
GO:0035913	biolink:NamedThing	ventral aorta morphogenesis	The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.	got7fsn_ti							bf	2011-06-24T11:24:36Z						biological_process											owl:Class	
GO:0035908	biolink:NamedThing	ventral aorta development	The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.	got7fsn_ti							bf	2011-06-24T11:08:49Z						biological_process											owl:Class	
GO:0021803	biolink:NamedThing	extension of leading cell process to pial surface	The extension of a long process to the pial surface as a cell leaves the ventricular zone.	got7fsn_ti														biological_process											owl:Class	
GO:0021802	biolink:NamedThing	somal translocation	The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate.	got7fsn_ti	perikaryal translocation of Morest													biological_process											owl:Class	
GO:0045804	biolink:NamedThing	negative regulation of eclosion	Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.	got7fsn_ti	down-regulation of eclosion|inhibition of eclosion|downregulation of eclosion|down regulation of eclosion													biological_process											owl:Class	
GO:0005350	biolink:NamedThing	pyrimidine nucleobase transmembrane transporter activity	Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.	got7fsn_ti	pyrimidine base transmembrane transporter activity|pyrimidine transmembrane transporter activity													molecular_function											owl:Class	
GO:0005739	biolink:NamedThing	mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.	got7fsn_ti	mitochondria				Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.)							Wikipedia:Mitochondrion|NIF_Subcellular:sao1860313010		cellular_component											owl:Class	
NCBITaxon:9443	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008335	biolink:NamedThing	female germline ring canal stabilization	Maintenance of the structural integrity of the ring canals connecting the female germline cyst.	got7fsn_ti	nurse cell ring canal stabilization|ovarian ring canal stabilization													biological_process											owl:Class	
GO:2000767	biolink:NamedThing	positive regulation of cytoplasmic translation	Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.	got7fsn_ti							vw	2011-06-20T10:39:26Z						biological_process											owl:Class	
GO:0035679	biolink:NamedThing	anterior lateral line neuromast hair cell morphogenesis	The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.	got7fsn_ti							bf	2011-02-14T11:06:54Z						biological_process											owl:Class	
GO:0035676	biolink:NamedThing	anterior lateral line neuromast hair cell development	The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti							bf	2011-02-14T11:03:57Z						biological_process											owl:Class	
GO:1905283	biolink:NamedThing	negative regulation of epidermal growth factor receptor signaling pathway involved in heart process	Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.	got7fsn_ti	inhibition of ERBB1 signaling pathway involved in heart process|negative regulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|inhibition of EGF receptor signalling pathway involved in cardiac process|downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signalling pathway involved in heart process|inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of EGFR signaling pathway involved in heart process|inhibition of EGF receptor signalling pathway involved in heart process|downregulation of EGF receptor signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signalling pathway involved in heart process|down-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|downregulation of EGFR signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in heart process|downregulation of ERBB1 signaling pathway involved in heart process|inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signalling pathway involved in cardiac process|down-regulation of ERBB1 signaling pathway involved in cardiac process|downregulation of EGF receptor signalling pathway involved in heart process|down-regulation of epidermal growth factor receptor signalling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in heart process|down regulation of EGFR signaling pathway involved in heart process|downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|downregulation of EGFR signaling pathway involved in heart process|down regulation of ERBB1 signaling pathway involved in heart process|down regulation of EGF receptor signalling pathway involved in cardiac process|negative regulation of EGF receptor signalling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signalling pathway involved in heart process|down regulation of EGF receptor signaling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|negative regulation of ERBB1 signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signaling pathway involved in heart process|inhibition of epidermal growth factor receptor signalling pathway involved in cardiac process|inhibition of EGF receptor signaling pathway involved in heart process|down-regulation of EGF receptor signalling pathway involved in heart process|inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down-regulation of ERBB1 signaling pathway involved in heart process|down regulation of EGFR signaling pathway involved in cardiac process|negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down regulation of ERBB1 signaling pathway involved in cardiac process|inhibition of EGF receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signalling pathway involved in heart process|down-regulation of EGF receptor signalling pathway involved in cardiac process|inhibition of EGFR signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in heart process|down-regulation of EGFR signaling pathway involved in cardiac process|downregulation of EGF receptor signaling pathway involved in heart process|down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in cardiac process|down-regulation of EGF receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signalling pathway involved in heart process|negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|inhibition of ERBB1 signaling pathway involved in cardiac process|downregulation of EGF receptor signalling pathway involved in cardiac process|down regulation of EGF receptor signaling pathway involved in heart process|inhibition of EGFR signaling pathway involved in cardiac process|down-regulation of EGF receptor signaling pathway involved in cardiac process|downregulation of ERBB1 signaling pathway involved in cardiac process|down regulation of EGF receptor signalling pathway involved in heart process|down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of ERBB1 signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in heart process						bc	2016-06-20T14:40:49Z						biological_process											owl:Class	
GO:0008917	biolink:NamedThing	lipopolysaccharide N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide.	got7fsn_ti	uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase activity|LPS N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase activity											MetaCyc:2.4.1.56-RXN|EC:2.4.1.56		molecular_function											owl:Class	
GO:0048355	biolink:NamedThing	root cap mucilage biosynthetic process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth.	got7fsn_ti	root cap mucilage formation|root cap mucilage synthesis|root cap mucilage biosynthesis|root cap mucilage anabolism													biological_process											owl:Class	
GO:0048360	biolink:NamedThing	root cap mucilage metabolic process	The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth.	got7fsn_ti	root cap mucilage metabolism													biological_process											owl:Class	
GO:0090220	biolink:NamedThing	chromosome localization to nuclear envelope involved in homologous chromosome segregation	The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis.	got7fsn_ti	chromosome localisation to nuclear envelope involved in homologous chromosome segregation						tb	2010-01-13T10:20:33Z						biological_process											owl:Class	
GO:0061830	biolink:NamedThing	concave side of sperm head	The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species.	got7fsn_ti														cellular_component											owl:Class	
GO:0072322	biolink:NamedThing	protein transport across periplasmic space	The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall.	got7fsn_ti	chaperone-mediated protein transport across periplasmic space	https://github.com/geneontology/go-ontology/issues/15917					mah	2010-10-28T04:24:59Z			GO:0072323			biological_process											owl:Class	
GO:0140597	biolink:NamedThing	protein carrier activity	Binding to and carrying a protein between two different cellular locations by moving along with the target protein.	got7fsn_ti	protein chaperone|protein carrier chaperone	https://github.com/geneontology/go-ontology/issues/15917					pg	2021-02-10T06:16:16Z						molecular_function											owl:Class	
GO:0000795	biolink:NamedThing	synaptonemal complex	A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other.  Transverse filaments connect the lateral elements to the central element.	got7fsn_ti											GO:0005716	Wikipedia:Synaptonemal_complex		cellular_component											owl:Class	
GO:0021765	biolink:NamedThing	cingulate gyrus development	The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.	got7fsn_ti														biological_process											owl:Class	
GO:0021761	biolink:NamedThing	limbic system development	The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.	got7fsn_ti														biological_process											owl:Class	
GO:0042713	biolink:NamedThing	sperm ejaculation	The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.	got7fsn_ti														biological_process											owl:Class	
GO:0061844	biolink:NamedThing	antimicrobial humoral immune response mediated by antimicrobial peptide	An immune response against microbes mediated by anti-microbial peptides in body fluid.	got7fsn_ti	antimicrobial peptide-mediated antimicrobial humoral response|peptide-mediated antimicrobial humoral response													biological_process											owl:Class	
GO:0043845	biolink:NamedThing	DNA polymerase III, proofreading complex	A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity.	got7fsn_ti	DNA polymerase III, proofreading subcomplex|DNA polymerase III, proof-reading complex|DNA polymerase III, proof-reading subcomplex													cellular_component											owl:Class	
GO:0044776	biolink:NamedThing	DNA polymerase III, core complex	The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities.	got7fsn_ti							jl	2013-03-13T14:09:38Z						cellular_component											owl:Class	
GO:0048816	biolink:NamedThing	ocellus morphogenesis	The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.	got7fsn_ti														biological_process											owl:Class	
GO:0007455	biolink:NamedThing	eye-antennal disc morphogenesis	The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.	got7fsn_ti	eye-antennal disc metamorphosis													biological_process											owl:Class	
GO:0003406	biolink:NamedThing	retinal pigment epithelium development	The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.	got7fsn_ti	RPE development						dph	2009-12-21T02:04:27Z						biological_process											owl:Class	
GO:0002634	biolink:NamedThing	regulation of germinal center formation	Any process that modulates the frequency, rate, or extent of germinal center formation.	got7fsn_ti														biological_process											owl:Class	
GO:0060900	biolink:NamedThing	embryonic camera-type eye formation	The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.	got7fsn_ti							dph	2009-08-13T02:26:54Z						biological_process											owl:Class	
GO:0032778	biolink:NamedThing	P-type cobalt transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in).	got7fsn_ti	cobalt transporting ATPase activity|ATPase-coupled cobalt transmembrane transporter activity|ATP-dependent cobalt transmembrane transporter activity|cobalt-transporting ATPase activity|cobalt porter activity										GO:0015632	RHEA:32779		molecular_function											owl:Class	
GO:0006824	biolink:NamedThing	cobalt ion transport	The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	cobalt transport													biological_process											owl:Class	
GO:1905938	biolink:NamedThing	positive regulation of germ cell proliferation	Any process that activates or increases the frequency, rate or extent of germ cell proliferation.	got7fsn_ti	activation of germ cell proliferation|up-regulation of germ cell proliferation|upregulation of germ cell proliferation|up regulation of germ cell proliferation						hbye	2017-02-09T14:51:51Z						biological_process											owl:Class	
GO:0004921	biolink:NamedThing	interleukin-11 receptor activity	Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-11R|gp130|IL-11 receptor activity													molecular_function											owl:Class	
GO:0038154	biolink:NamedThing	interleukin-11-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-11 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-11-mediated signaling pathway|interleukin-11-mediated signalling pathway						bf	2012-05-11T11:48:37Z						biological_process											owl:Class	
GO:0090394	biolink:NamedThing	negative regulation of excitatory postsynaptic potential	Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	got7fsn_ti	reduction of excitatory postsynaptic membrane potential|negative regulation of EPSP|negative regulation of excitatory post-synaptic membrane potential						tb	2010-12-15T01:43:12Z						biological_process											owl:Class	
GO:0006413	biolink:NamedThing	translational initiation	The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.	got7fsn_ti	biopolymerisation|biopolymerization|protein synthesis initiation|translation initiation										GO:0006454|GO:0006440			biological_process											owl:Class	
GO:0008384	biolink:NamedThing	IkappaB kinase activity	Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.	got7fsn_ti	IKK|inhibitor of NFkappaB kinase activity|inhibitor of NF-kappaB kinase activity|TBK1|IKK-1|ATP:IkappaB protein phosphotransferase activity|STK12|ikappaB kinase activity|IKBKA|IKBKB|CHUK|TANK-binding kinase 1 activity|IKK-2				Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB.							EC:2.7.11.10|Reactome:R-HSA-5684275|Reactome:R-HSA-5684267|MetaCyc:2.7.11.10-RXN|RHEA:19073		molecular_function											owl:Class	
GO:0007252	biolink:NamedThing	I-kappaB phosphorylation	The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.	got7fsn_ti	IKB phosphorylation|inhibitor of NF-kappaB phosphorylation|IkappaB phosphorylation|inhibitor of kappaB phosphorylation													biological_process											owl:Class	
GO:0036241	biolink:NamedThing	glutamate catabolic process to 4-hydroxybutyrate	The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate.	got7fsn_ti	glutamate degradation to 4-hydroxybutyrate				In the catabolism of glutamate in mammals, succinate semialdehyde is converted to succinate (see GO:0006540). Plants can utilize an alternative route, converting succinic semialdehyde to 4-hydroxybutyrate using gamma-hydroxybutyrate dehydrogenase.		bf	2012-05-23T02:17:05Z						biological_process											owl:Class	
GO:0047577	biolink:NamedThing	4-hydroxybutyrate dehydrogenase activity	Catalysis of the reaction: 4-hydroxybutanoate + NAD(+) = H(+) + NADH + succinate semialdehyde.	got7fsn_ti	gamma-hydroxybutyrate dehydrogenase activity|4-hydroxybutanoate:NAD+ oxidoreductase activity											EC:1.1.1.61|MetaCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|KEGG_REACTION:R01644|RHEA:23948		molecular_function											owl:Class	
GO:0010159	biolink:NamedThing	specification of animal organ position	The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ.	got7fsn_ti														biological_process											owl:Class	
GO:0035857	biolink:NamedThing	eosinophil fate specification	The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	got7fsn_ti	eosinophil cell fate specification						bf	2011-05-17T10:42:54Z						biological_process											owl:Class	
GO:0035854	biolink:NamedThing	eosinophil fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin.	got7fsn_ti	eosinophil cell fate commitment						bf	2011-05-13T01:23:28Z						biological_process											owl:Class	
GO:2000033	biolink:NamedThing	regulation of seed dormancy process	Any process that modulates the frequency, rate or extent of seed dormancy process.	got7fsn_ti	regulation of seed dormancy						tb	2010-08-05T11:33:13Z						biological_process											owl:Class	
GO:0044663	biolink:NamedThing	establishment or maintenance of cell type involved in phenotypic switching	A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.	got7fsn_ti							jl	2012-08-07T14:30:07Z						biological_process											owl:Class	
GO:0036166	biolink:NamedThing	phenotypic switching	A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.	got7fsn_ti	phenotypic dimorphism				Mating type switching is not considered a type of phenotypic switching: for mating type switching, consider instead annotating to 'mating type switching ; GO:0007533'.		bf	2012-03-27T01:31:28Z						biological_process											owl:Class	
GO:0085036	biolink:NamedThing	extrahaustorial matrix	The space between the symbiont plasma membrane and the extrahaustorial membrane of the host.	got7fsn_ti					See also: haustorium ; GO:0085035 and extrahaustorial membrane ; GO:0085037.		jl	2010-07-27T03:58:20Z						cellular_component											owl:Class	
GO:1905956	biolink:NamedThing	positive regulation of endothelial tube morphogenesis	Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.	got7fsn_ti	up-regulation of endothelial tube morphogenesis|upregulation of endothelial tube morphogenesis|up regulation of endothelial tube morphogenesis|activation of endothelial tube morphogenesis						rph	2017-02-21T15:17:39Z						biological_process											owl:Class	
GO:0030958	biolink:NamedThing	RITS complex	A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing.	got7fsn_ti														cellular_component											owl:Class	
GO:0035748	biolink:NamedThing	myelin sheath abaxonal region	The region of the myelin sheath furthest from the axon.	got7fsn_ti							bf	2011-03-23T10:16:14Z						cellular_component											owl:Class	
GO:0035253	biolink:NamedThing	ciliary rootlet	A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.	got7fsn_ti	cilium rootlet|cilial rootlet													cellular_component											owl:Class	
GO:0021869	biolink:NamedThing	forebrain ventricular zone progenitor cell division	The mitotic division of a basal progenitor giving rise to two neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0060637	biolink:NamedThing	positive regulation of lactation by mesenchymal-epithelial cell signaling	The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.	got7fsn_ti	positive regulation of lactation by mesenchymal-epithelial cell signalling						dph	2009-05-19T03:39:24Z						biological_process											owl:Class	
GO:0098849	biolink:NamedThing	cellular detoxification of cadmium ion	Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.	got7fsn_ti														biological_process											owl:Class	
GO:0071276	biolink:NamedThing	cellular response to cadmium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	got7fsn_ti	cellular response to cadmium						mah	2009-12-10T03:54:49Z						biological_process											owl:Class	
GO:0035043	biolink:NamedThing	male pronuclear envelope synthesis	Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation.	got7fsn_ti														biological_process											owl:Class	
GO:0035039	biolink:NamedThing	male pronucleus assembly	The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.	got7fsn_ti	male pronucleus formation													biological_process											owl:Class	
GO:0030316	biolink:NamedThing	osteoclast differentiation	The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.	got7fsn_ti	osteoclast cell differentiation													biological_process											owl:Class	
GO:0045239	biolink:NamedThing	tricarboxylic acid cycle enzyme complex	Any of the heteromeric enzymes that act in the TCA cycle.	got7fsn_ti	TCA cycle enzyme complex													cellular_component											owl:Class	
GO:0098501	biolink:NamedThing	polynucleotide dephosphorylation	The process of removing one or more phosphate groups from a polynucleotide.	got7fsn_ti							dos	2013-09-18T14:49:10Z						biological_process											owl:Class	
GO:0045729	biolink:NamedThing	respiratory burst at fertilization	The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes.	got7fsn_ti	metabolic burst at fertilization|oxidative burst at fertilization													biological_process											owl:Class	
GO:1905027	biolink:NamedThing	regulation of membrane depolarization during AV node cell action potential	Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential.	got7fsn_ti	regulation of membrane depolarization during AV node cardiac muscle cell action potential|regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential						rph	2016-03-04T13:46:06Z						biological_process											owl:Class	
GO:0086016	biolink:NamedThing	AV node cell action potential	An action potential that occurs in an atrioventricular node cardiac muscle cell.	got7fsn_ti	AV node cardiac muscle cell action potential|atrioventricular node cardiac muscle cell action potential						tb	2011-11-10T08:58:56Z						biological_process											owl:Class	
GO:0120157	biolink:NamedThing	PAR polarity complex	A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC.	got7fsn_ti	BEM1-CDC24-CLA4 complex|PAR6-PAR3-aPKC complex|apical polarity complex|Cdc42p GEF-PAK complex|PAR3-PAR6-atypical PKC|PAR3/PAR6/aPKC				"This tripartite complex named PAR6/PAR3/aPKC is conserved from worms to vertebrates" (PMID:18005931). In yeast, the components are BEM1, CDC24, and CLA4.		krc	2018-05-11T15:41:30Z						cellular_component											owl:Class	
GO:0035023	biolink:NamedThing	regulation of Rho protein signal transduction	Any process that modulates the frequency, rate or extent of Rho protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:0006998	biolink:NamedThing	nuclear envelope organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.	got7fsn_ti	nuclear envelope organisation|nuclear envelope organization and biogenesis													biological_process											owl:Class	
GO:0010256	biolink:NamedThing	endomembrane system organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.	got7fsn_ti	endomembrane system organisation|endomembrane organization													biological_process											owl:Class	
GO:0003147	biolink:NamedThing	neural crest cell migration involved in heart formation	The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.	got7fsn_ti							tb	2009-09-22T04:29:55Z						biological_process											owl:Class	
GO:0061308	biolink:NamedThing	cardiac neural crest cell development involved in heart development	The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.	got7fsn_ti							dph	2010-09-23T09:01:49Z						biological_process											owl:Class	
GO:0015126	biolink:NamedThing	canalicular bile acid transmembrane transporter activity	The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.	got7fsn_ti														molecular_function											owl:Class	
GO:0043312	biolink:NamedThing	neutrophil degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.	got7fsn_ti	neutrophil granule exocytosis|heterophil degranulation													biological_process											owl:Class	
GO:0002446	biolink:NamedThing	neutrophil mediated immunity	Any process involved in the carrying out of an immune response by a neutrophil.	got7fsn_ti														biological_process											owl:Class	
GO:0097091	biolink:NamedThing	synaptic vesicle clustering	The process that results in grouping synaptic vesicles in presynaptic structures.	got7fsn_ti		https://github.com/geneontology/synapse/issues/163					pr	2011-07-04T01:48:24Z						biological_process											owl:Class	
GO:0099504	biolink:NamedThing	synaptic vesicle cycle	A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.	got7fsn_ti														biological_process											owl:Class	
GO:0048163	biolink:NamedThing	scattered antral spaces stage	The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration.	got7fsn_ti	mammalian oogenesis stage 6													biological_process											owl:Class	
GO:0061203	biolink:NamedThing	striated muscle paramyosin thick filament assembly	The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle.	got7fsn_ti							dph	2010-07-29T12:22:31Z						biological_process											owl:Class	
GO:1990394	biolink:NamedThing	cellular response to cell wall damage	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell.	got7fsn_ti							al	2014-06-05T16:45:33Z						biological_process											owl:Class	
GO:0071433	biolink:NamedThing	cell wall repair	A process of cell wall organization that results in the restoration of the cell wall following damage.	got7fsn_ti							mah	2009-12-16T11:00:50Z						biological_process											owl:Class	
GO:0050902	biolink:NamedThing	leukocyte adhesive activation	The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.	got7fsn_ti	leukocyte adhesive triggering													biological_process											owl:Class	
NCBITaxon:131567	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007285	biolink:NamedThing	primary spermatocyte growth	The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0120309	biolink:NamedThing	cilium attachment to cell body	A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species.	got7fsn_ti	cilial attachment to cell body|ciliary attachment to cell body|flagellum attachment to cell body|flagellar attachment to cell body						krc	2021-03-23T18:01:14Z						biological_process											owl:Class	
NCBITaxon:5653	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009566	biolink:NamedThing	fertilization	The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).	got7fsn_ti	syngamy	https://github.com/geneontology/go-ontology/issues/20176										Wikipedia:Fertilisation		biological_process											owl:Class	
GO:0005960	biolink:NamedThing	glycine cleavage complex	A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T.	got7fsn_ti	glycine dehydrogenase (decarboxylating) complex|glycine decarboxylase complex|glycine dehydrogenase complex (decarboxylating)|glycine cleavage system|glycine synthase complex										GO:0005961|GO:0070015	Wikipedia:Glycine_decarboxylase_complex		cellular_component											owl:Class	
GO:0014906	biolink:NamedThing	myotube cell development involved in skeletal muscle regeneration	The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	got7fsn_ti														biological_process											owl:Class	
GO:0014908	biolink:NamedThing	myotube differentiation involved in skeletal muscle regeneration	The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	got7fsn_ti														biological_process											owl:Class	
GO:0106125	biolink:NamedThing	reservosome matrix	A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome.	got7fsn_ti							hjd	2018-05-03T18:00:03Z						cellular_component											owl:Class	
NCBITaxon:47570	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035060	biolink:NamedThing	brahma complex	A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof.	got7fsn_ti	BRM complex													cellular_component											owl:Class	
GO:0019862	biolink:NamedThing	IgA binding	Binding to an immunoglobulin of an IgA isotype.	got7fsn_ti														molecular_function											owl:Class	
GO:0072766	biolink:NamedThing	centromere clustering at the mitotic interphase nuclear envelope	The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei.	got7fsn_ti	kinetochore clustering at the old mitotic spindle pole body|centromere clustering at the nuclear periphery|rabl configuration|kinetochore clustering at spindle pole body|kinetochore localization at spindle pole body|centromere-SPB clustering|centromere clustering at the mitotic nuclear envelope|kinetochore clustering at SPB	https://github.com/geneontology/go-ontology/issues/19227|https://github.com/geneontology/go-ontology/issues/20122					mah	2012-11-21T13:32:22Z						biological_process											owl:Class	
CHEBI:17996	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048570	biolink:NamedThing	notochord morphogenesis	The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.	got7fsn_ti														biological_process											owl:Class	
GO:0036507	biolink:NamedThing	protein demannosylation	The removal of one or more mannose residues from a mannosylated protein.	got7fsn_ti	protein de-mannosylation				Consider also annotating to the term 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T13:57:01Z						biological_process											owl:Class	
GO:0072288	biolink:NamedThing	metanephric proximal tubule morphogenesis	The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.	got7fsn_ti							mah	2010-04-09T03:42:03Z						biological_process											owl:Class	
GO:0070825	biolink:NamedThing	micropyle	An external encapsulating structure part of the chorion. A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization.	got7fsn_ti							mah	2009-07-21T05:33:09Z						cellular_component											owl:Class	
GO:0048132	biolink:NamedThing	female germ-line stem cell asymmetric division	The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.	got7fsn_ti	female germ-line stem cell renewal										GO:0048141			biological_process											owl:Class	
GO:0007462	biolink:NamedThing	R1/R6 cell fate commitment	The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres.	got7fsn_ti														biological_process											owl:Class	
GO:0048052	biolink:NamedThing	R1/R6 cell differentiation	The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0099078	biolink:NamedThing	BORC complex	A protein complex that is invovled in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors.	got7fsn_ti														cellular_component											owl:Class	
GO:0032418	biolink:NamedThing	lysosome localization	Any process in which a lysosome is transported to, and/or maintained in, a specific location.	got7fsn_ti	lysosome localisation													biological_process											owl:Class	
GO:0008069	biolink:NamedThing	dorsal/ventral axis specification, ovarian follicular epithelium	Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	dorsal/ventral axis determination, ovarian follicular epithelium|dorsal/ventral axis determination, follicular epithelium|dorsoventral axis specification, ovarian follicular epithelium|dorsal-ventral axis specification, ovarian follicular epithelium													biological_process											owl:Class	
GO:0031054	biolink:NamedThing	pre-miRNA processing	Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.	got7fsn_ti	pre-microRNA processing													biological_process											owl:Class	
GO:1904564	biolink:NamedThing	Nbp35-Cfd1 ATPase complex	An iron-sulfur cluster assembly complex that is capable of weak ATPase activity. In yeast it consists of two subunits, Nbp35 and Cfd1.	got7fsn_ti							rb	2015-08-18T22:50:29Z						cellular_component											owl:Class	
GO:0016887	biolink:NamedThing	ATP hydrolysis activity	Catalysis of the reaction: ATP + H2O = ADP + H+ Pi. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.	got7fsn_ti	adenosinetriphosphatase activity|ATP monophosphatase activity|adenosine triphosphatase activity|adenosine 5'-triphosphatase activity|ATP phosphohydrolase activity|ATPase|ATP hydrolase activity	https://github.com/geneontology/go-ontology/issues/20498|https://github.com/geneontology/go-ontology/issues/19078|https://github.com/geneontology/go-ontology/issues/21612			Note that this term is meant to specifically represent the ATPase activity of proteins using ATPase as a source of energy to drive a reaction. If possible, gene products should also be annotated to a child of 'ATP-dependent activity ; GO:0140657', to capture their overall function.						GO:0004002|GO:0042623	Reactome:R-HSA-9706399|Reactome:R-HSA-6811422|Reactome:R-HSA-5654989|Reactome:R-HSA-5694425|Reactome:R-HSA-917693|Reactome:R-HSA-6814670|Reactome:R-HSA-159101|Reactome:R-HSA-9668415|Reactome:R-HSA-72139|Reactome:R-HSA-5618093|Reactome:R-HSA-6814683|Reactome:R-HSA-6809015|Reactome:R-HSA-9609860|Reactome:R-HSA-8868658|Reactome:R-HSA-6814678|Reactome:R-HSA-8847638|Reactome:R-HSA-8939203|Reactome:R-HSA-416985|RHEA:13065|Reactome:R-HSA-3371422|Reactome:R-HSA-9038161		molecular_function											owl:Class	
GO:0070724	biolink:NamedThing	BMP receptor complex	A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.	got7fsn_ti	bone morphogenetic protein receptor complex						mah	2009-06-15T02:34:27Z						cellular_component											owl:Class	
GO:0004911	biolink:NamedThing	interleukin-2 receptor activity	Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-2R|IL-2 receptor activity													molecular_function											owl:Class	
GO:0038110	biolink:NamedThing	interleukin-2-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-2-mediated signaling pathway|interleukin-2-mediated signalling pathway						bf	2012-03-22T10:18:29Z						biological_process											owl:Class	
GO:0004912	biolink:NamedThing	interleukin-3 receptor activity	Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-3 receptor activity|IL-3R											Wikipedia:Interleukin-3_receptor		molecular_function											owl:Class	
GO:0071553	biolink:NamedThing	G protein-coupled pyrimidinergic nucleotide receptor activity	Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G-protein coupled pyrimidinergic nucleotide receptor activity|pyrimidinergic nucleotide receptor activity, G-protein coupled|G protein coupled pyrimidinergic nucleotide receptor activity|pyrimidinergic nucleotide receptor activity, G protein coupled						mah	2010-01-13T03:13:22Z						molecular_function											owl:Class	
GO:0019103	biolink:NamedThing	pyrimidine nucleotide binding	Binding to a pyrimidine nucleotide, a pyrimidine nucleoside esterified with (ortho)phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0010207	biolink:NamedThing	photosystem II assembly	The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms.	got7fsn_ti														biological_process											owl:Class	
GO:0031968	biolink:NamedThing	organelle outer membrane	The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0033759	biolink:NamedThing	flavone synthase activity	Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O.	got7fsn_ti	flavone synthase I activity|FNS I|flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating) activity											EC:1.14.20.5|RHEA:10448|MetaCyc:RXN-8000		molecular_function											owl:Class	
GO:0000749	biolink:NamedThing	response to pheromone triggering conjugation with cellular fusion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	response to pheromone during conjugation with cellular fusion										GO:0007328|GO:0030434			biological_process											owl:Class	
GO:0099574	biolink:NamedThing	regulation of protein catabolic process at synapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating protein degradation at the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0036055	biolink:NamedThing	protein-succinyllysine desuccinylase activity	Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.	got7fsn_ti	succinyl lysine desuccinylase activity|succinyllysine desuccinylase activity|peptidyl-succinyllysine desuccinylase activity				This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide.		bf	2011-12-12T01:33:51Z				RHEA:47668		molecular_function											owl:Class	
GO:0036049	biolink:NamedThing	peptidyl-lysine desuccinylation	The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein.	got7fsn_ti							bf	2011-12-12T09:44:54Z						biological_process											owl:Class	
GO:0021993	biolink:NamedThing	initiation of neural tube closure	The process in which closure points are established at multiple points and along the neural rostrocaudal axis.	got7fsn_ti														biological_process											owl:Class	
GO:0001843	biolink:NamedThing	neural tube closure	The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.	got7fsn_ti														biological_process											owl:Class	
GO:0042680	biolink:NamedThing	compound eye cone cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti											GO:0042677			biological_process											owl:Class	
GO:0042676	biolink:NamedThing	compound eye cone cell fate commitment	The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type.	got7fsn_ti											GO:0007466			biological_process											owl:Class	
GO:0044386	biolink:NamedThing	integral to host endoplasmic reticulum membrane	Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. Occurring in a host cell.	got7fsn_ti							jl	2011-12-13T04:11:30Z						cellular_component											owl:Class	
GO:0003316	biolink:NamedThing	establishment of myocardial progenitor cell apical/basal polarity	The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment.	got7fsn_ti	myocardial progenitor epithelial polarization						dph	2009-10-27T09:01:26Z						biological_process											owl:Class	
GO:0003315	biolink:NamedThing	heart rudiment formation	The developmental process pertaining to the initial formation of the heart rudiment.	got7fsn_ti	heart cone formation						dph	2009-10-27T08:43:37Z						biological_process											owl:Class	
GO:0016281	biolink:NamedThing	eukaryotic translation initiation factor 4F complex	The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.	got7fsn_ti	eukaryotic translation initiation factor 4 complex|eIF-4F													cellular_component											owl:Class	
GO:0097427	biolink:NamedThing	microtubule bundle	An arrangement of closely apposed microtubules running parallel to each other.	got7fsn_ti	microtubule fascicle						pr	2012-11-07T15:01:27Z				NIF_Subcellular:sao1872343973		cellular_component											owl:Class	
GO:1990509	biolink:NamedThing	PYM-mago-Y14 complex	Protein complex involved in the disassembly of Mago-Y14 from the spliced mRNA during first round of translation, independently of the translational machinery. Conserved from fission yeast to humans.	got7fsn_ti	PYM-mago-RNA-binding protein 8A complex|wibg-mago-tsu complex				An example of this is wibg in Drosophila melanogaster (P82804) in PMID:14968132 (inferred from physical interaction).		bhm	2014-10-03T12:52:01Z						cellular_component											owl:Class	
GO:2000624	biolink:NamedThing	positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.	got7fsn_ti	positive regulation of mRNA degradation, nonsense-mediated decay|positive regulation of mRNA catabolic process, nonsense-mediated|positive regulation of nonsense-mediated mRNA decay|positive regulation of nuclear mRNA catabolic process, nonsense-mediated decay|positive regulation of mRNA breakdown, nonsense-mediated decay|positive regulation of mRNA catabolism, nonsense-mediated						pr	2011-04-18T03:32:49Z						biological_process											owl:Class	
GO:0014844	biolink:NamedThing	myoblast proliferation involved in skeletal muscle regeneration	The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0097282	biolink:NamedThing	immunoglobulin-mediated neutralization	The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.	got7fsn_ti	antibody-mediated neutralization						pr	2012-03-26T01:55:24Z						biological_process											owl:Class	
GO:0034108	biolink:NamedThing	positive regulation of erythrocyte clearance	Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance.	got7fsn_ti	positive regulation of neocytolysis|positive regulation of RBC clearance|positive regulation of red blood cell clearance													biological_process											owl:Class	
GO:0046930	biolink:NamedThing	pore complex	A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids.	got7fsn_ti	pore-forming toxin activity|channel-forming toxin activity|pore	https://github.com/geneontology/go-ontology/issues/20452												cellular_component											owl:Class	
GO:0007084	biolink:NamedThing	mitotic nuclear membrane reassembly	The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge.	got7fsn_ti	nuclear envelope repair|mitotic nuclear envelope reassembly|nuclear envelope resealing	https://github.com/geneontology/go-ontology/issues/20636|https://github.com/geneontology/go-ontology/issues/19950												biological_process											owl:Class	
GO:0030206	biolink:NamedThing	chondroitin sulfate biosynthetic process	The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.	got7fsn_ti	chondroitin sulphate biosynthesis|chondroitin sulfate anabolism|chondroitin sulphate biosynthetic process|chondroitin sulfate formation|chondroitin sulfate biosynthesis|chondroitin sulfate synthesis													biological_process											owl:Class	
GO:0050650	biolink:NamedThing	chondroitin sulfate proteoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.	got7fsn_ti	chondroitin sulfate proteoglycan formation|chondroitin sulfate proteoglycan synthesis|chondroitin sulphate proteoglycan biosynthesis|chondroitin sulphate proteoglycan biosynthetic process|chondroitin sulfate proteoglycan biosynthesis|chondroitin sulfate proteoglycan anabolism													biological_process											owl:Class	
GO:0048623	biolink:NamedThing	seed germination on parent plant	The process in which a seed germinates before being shed from the parent plant.	got7fsn_ti	non-vegetative vivipary|vivipary|pre-harvest sprouting													biological_process											owl:Class	
GO:0021512	biolink:NamedThing	spinal cord anterior/posterior patterning	The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.	got7fsn_ti	spinal cord rostrocaudal patterning|spinal cord anterior-posterior patterning													biological_process											owl:Class	
GO:0021511	biolink:NamedThing	spinal cord patterning	The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.	got7fsn_ti														biological_process											owl:Class	
GO:0001989	biolink:NamedThing	positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure.	got7fsn_ti	positive regulation of the force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure|increased force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure|increased strength of cardiac contraction during baroreceptor response to decreased blood pressure													biological_process											owl:Class	
GO:0060314	biolink:NamedThing	regulation of ryanodine-sensitive calcium-release channel activity	Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														biological_process											owl:Class	
GO:0061438	biolink:NamedThing	renal system vasculature morphogenesis	The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.	got7fsn_ti							dph	2012-03-08T12:21:56Z						biological_process											owl:Class	
GO:0021933	biolink:NamedThing	radial glia guided migration of cerebellar granule cell	The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer.	got7fsn_ti														biological_process											owl:Class	
CHEBI:59888	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120009	biolink:NamedThing	intermembrane lipid transfer	The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-16T20:30:42Z						biological_process											owl:Class	
GO:0097527	biolink:NamedThing	necroptotic signaling pathway	A series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered.	got7fsn_ti	necroptosis signaling pathway|necroptotic signal transduction|necroptosis signaling|necroptotic signalling pathway				Gene products that may be annotated to this term include: 1) ligands such as TNF-alpha; 2) receptors such as TNFR (though care should be taken because TNF-alpha and TNFR may also be involved in non-necroptotic processes); 3) signaling molecules such as TNFR-associated death domain (TRADD), receptor-interacting protein kinase 1 (RIP1), cellular inhibitor of apoptosis 1 (cIAP1), cIAP2, TNFR-associated factor 2 (TRAF2) and TRAF5. Within the so-called complex I, RIP1 is polyubiquitinated by cIAPs, thereby providing a docking site for the recruitment of transforming growth factor beta (TGFbeta)-activated kinase 1 (TAK1), TAK1-binding protein 2 (TAB2) and TAB3 (which together deliver a pro-survival signal by activating the transcription factor NF-kB). In some pathophysiological and experimental settings, and in particular when caspase-8 is absent or when caspases are inhibited by pharmacological agents, cylindromatosis (CYLD)-deubiquitinated RIP1 engage in physical and functional interactions with its homolog RIP3, ultimately activating the execution of necrotic cell death. (The pathway downstream of RIPK3 remains largely unknown, although ROS generation, calcium overload, and the opening of the mitochondrial permeability transition pore have been implicated (PMID:22265414)). A necroptotic signaling pathway may also be induced by alkylating DNA damage (possibly by the overactivation of poly(ADP-ribose) polymerase 1, PARP1). This is sometimes referred to as PARP-dependent cell death or parthanatos; it is still being debated if it constitutes an independent cell death modality.		pr	2013-11-05T14:17:28Z						biological_process											owl:Class	
GO:0071689	biolink:NamedThing	muscle thin filament assembly	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.	got7fsn_ti							mah	2010-02-25T03:54:06Z						biological_process											owl:Class	
GO:0038004	biolink:NamedThing	epidermal growth factor receptor ligand maturation	Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor.	got7fsn_ti	EGFR ligand processing|peptide bond cleavage involved in EGFR ligand maturation|EGFR ligand maturation|peptide bond cleavage involved in epidermal growth factor receptor ligand maturation|epidermal growth factor receptor ligand processing|EGFR ligand maturation by peptide bond cleavage						bf	2011-06-07T03:08:41Z			GO:0038005			biological_process											owl:Class	
GO:0044787	biolink:NamedThing	bacterial-type DNA replication	The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome.	got7fsn_ti	bacterial-type cell cycle DNA replication						jl	2013-05-02T15:54:16Z						biological_process											owl:Class	
GO:0010548	biolink:NamedThing	regulation of thylakoid membrane disassembly	Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly.	got7fsn_ti	regulation of thylakoid membrane degradation													biological_process											owl:Class	
GO:0010547	biolink:NamedThing	thylakoid membrane disassembly	The controlled breakdown of the thylakoid membrane in the context of a normal process.	got7fsn_ti	thylakoid membrane degradation													biological_process											owl:Class	
GO:1903377	biolink:NamedThing	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.	got7fsn_ti	downregulation of neuron apoptosis in response to oxidative stress|down regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of neuron apoptosis in response to oxidative stress|down-regulation of neuron apoptosis in response to oxidative stress|down-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|neuroprotection against oxidative stress-induced apoptosis|down regulation of neuron apoptosis in response to oxidative stress|protection against oxidative stress-induced neuron apoptosis|inhibition of neuron apoptosis in response to oxidative stress|downregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of oxidative stress-induced neuron apoptosis|inhibition of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|protection against oxidative stress-induced neuronal apoptosis|negative regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress						bf	2014-08-26T13:03:28Z						biological_process											owl:Class	
GO:0051402	biolink:NamedThing	neuron apoptotic process	Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.	got7fsn_ti	neuronal cell programmed cell death by apoptosis|programmed cell death, neurons|programmed cell death of neurons by apoptosis|neuron programmed cell death by apoptosis|neuron apoptosis|apoptosis of neuronal cells|programmed cell death, neuronal cells|neuronal cell apoptosis|programmed cell death of neuronal cells by apoptosis|apoptosis of neurons													biological_process											owl:Class	
GO:0099529	biolink:NamedThing	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel).	got7fsn_ti														molecular_function											owl:Class	
GO:0030323	biolink:NamedThing	respiratory tube development	The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract.	got7fsn_ti														biological_process											owl:Class	
GO:0035776	biolink:NamedThing	pronephric proximal tubule development	The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.	got7fsn_ti							bf	2011-04-04T11:02:54Z						biological_process											owl:Class	
GO:0061305	biolink:NamedThing	maintenance of bipolar cell polarity regulating cell shape	The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.	got7fsn_ti							dph	2010-09-16T09:25:18Z						biological_process											owl:Class	
GO:0033577	biolink:NamedThing	protein glycosylation in endoplasmic reticulum	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum.	got7fsn_ti	core glycosylation|protein amino acid glycosylation in endoplasmic reticulum|protein amino acid glycosylation in ER													biological_process											owl:Class	
GO:0007210	biolink:NamedThing	serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.	got7fsn_ti	serotonin receptor signalling pathway													biological_process											owl:Class	
GO:1903351	biolink:NamedThing	cellular response to dopamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.	got7fsn_ti							mr	2014-08-19T19:33:35Z						biological_process											owl:Class	
GO:0008353	biolink:NamedThing	RNA polymerase II CTD heptapeptide repeat kinase activity	Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.	got7fsn_ti	[RNA-polymerase]-subunit kinase activity|CTD kinase activity|RNA polymerase II carboxy-terminal domain kinase activity|ATP:DNA-directed RNA polymerase phosphotransferase activity|RNA polymerase subunit kinase activity|STK9|RNA-polymerase-subunit kinase activity											EC:2.7.11.23|MetaCyc:RNA-POLYMERASE-SUBUNIT-KINASE-RXN|RHEA:10216|Reactome:R-HSA-170704|Reactome:R-HSA-167191|Reactome:R-HSA-170706		molecular_function											owl:Class	
GO:0072246	biolink:NamedThing	metanephric glomerular parietal epithelial cell development	The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	got7fsn_ti	metanephric Bowman's capsule development						mah	2010-03-19T03:42:13Z						biological_process											owl:Class	
GO:0072245	biolink:NamedThing	metanephric glomerular parietal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	got7fsn_ti							mah	2010-03-19T03:41:26Z						biological_process											owl:Class	
GO:1903859	biolink:NamedThing	regulation of dendrite extension	Any process that modulates the frequency, rate or extent of dendrite extension.	got7fsn_ti					An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype.		pad	2015-02-02T15:33:51Z						biological_process											owl:Class	
GO:0000902	biolink:NamedThing	cell morphogenesis	The developmental process in which the size or shape of a cell is generated and organized.	got7fsn_ti	cellular morphogenesis										GO:0045790|GO:0045791|GO:0007148			biological_process											owl:Class	
GO:1904146	biolink:NamedThing	positive regulation of meiotic cell cycle process involved in oocyte maturation	Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.	got7fsn_ti	up-regulation of meiotic cell cycle process involved in oocyte maturation|activation of meiotic cell cycle process involved in oocyte maturation|upregulation of meiotic cell cycle process involved in oocyte maturation|up regulation of meiotic cell cycle process involved in oocyte maturation						tb	2015-04-14T15:59:28Z						biological_process											owl:Class	
GO:0060616	biolink:NamedThing	mammary gland cord formation	The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.	got7fsn_ti	mammary gland sprout formation						dph	2009-05-18T08:57:58Z						biological_process											owl:Class	
GO:0032126	biolink:NamedThing	eisosome	A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization.	got7fsn_ti												Wikipedia:Eisosome		cellular_component											owl:Class	
GO:0016332	biolink:NamedThing	establishment or maintenance of polarity of embryonic epithelium	Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.	got7fsn_ti														biological_process											owl:Class	
GO:2001268	biolink:NamedThing	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.	got7fsn_ti	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|negative regulation of initiator caspase activity						pr	2011-12-13T07:56:21Z						biological_process											owl:Class	
GO:0140041	biolink:NamedThing	cellular detoxification of methylglyoxal	Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal.	got7fsn_ti							pg	2017-06-16T09:43:30Z						biological_process											owl:Class	
GO:0060100	biolink:NamedThing	positive regulation of phagocytosis, engulfment	Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0021886	biolink:NamedThing	hypothalamus gonadotrophin-releasing hormone neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter.	got7fsn_ti	hypothalamus gonadotropin-releasing hormone neuron differentiation													biological_process											owl:Class	
GO:0021667	biolink:NamedThing	rhombomere 6 morphogenesis	The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0021572	biolink:NamedThing	rhombomere 6 development	The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0005688	biolink:NamedThing	U6 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U6, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6 snRNP, most of which remain associated with the U6 snRNA both while the U6 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.	got7fsn_ti	snRNP U6													cellular_component											owl:Class	
GO:0120115	biolink:NamedThing	Lsm2-8 complex	A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus.	got7fsn_ti							krc	2017-11-06T18:56:22Z						cellular_component											owl:Class	
GO:0071001	biolink:NamedThing	U4/U6 snRNP	A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4 and U6, a heptameric ring of Sm proteins associated with U4, the Lsm2-8 heptameric ring complex associated with U6, as well as several proteins that are unique to the U4 snRNP or U6 snRNPs, some of which remain associated with the U4/U6 snRNA both while the U4 snRNP is free or assembled into a series of spliceosomal complexes.	got7fsn_ti							mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0097014	biolink:NamedThing	ciliary plasm	All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.	got7fsn_ti	microtubule-based flagellum cytoplasm|microtubule-based flagellar matrix|microtubule-based flagellar cytoplasm|microtubule-based flagellum matrix|cilial cytoplasm|ciliary cytoplasm|cilium plasm|cilium cytoplasm				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm".		pr	2011-03-23T01:52:31Z						cellular_component											owl:Class	
GO:0015552	biolink:NamedThing	propionate transmembrane transporter activity	Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.	got7fsn_ti														molecular_function											owl:Class	
GO:0015730	biolink:NamedThing	propanoate transport	The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	propionate transport													biological_process											owl:Class	
GO:0062097	biolink:NamedThing	chemosynthesis	The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane.	got7fsn_ti							dph	2018-11-29T13:18:55Z				Wikipedia:Chemosynthesis		biological_process											owl:Class	
GO:0097561	biolink:NamedThing	right caudal flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.	got7fsn_ti	right caudal cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:31:15Z						cellular_component											owl:Class	
GO:0090395	biolink:NamedThing	plant cell papilla	A cell projection that is a short, rounded projection from a plant epidermal cell.	got7fsn_ti					Part of papilla cell (PO:0025166), which is a shoot epidermal cell (PO:0025165) in plants. Replaces the obsolete term papillae (PO:0002001).		tb	2010-12-15T03:26:20Z						cellular_component											owl:Class	
GO:0030937	biolink:NamedThing	collagen type XVII trimer	A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices span the plasma membrane and associate with hemidesmosomes and the basal lamina where they bind laminin.	got7fsn_ti														cellular_component											owl:Class	
GO:0030056	biolink:NamedThing	hemidesmosome	A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.	got7fsn_ti	trans-epithelial attachment|fibrous organelle|epidermal attachment structure|hemi-adherens junction											Wikipedia:Hemidesmosome		cellular_component											owl:Class	
GO:1900248	biolink:NamedThing	negative regulation of cytoplasmic translational elongation	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.	got7fsn_ti	downregulation of cytoplasmic translational elongation|down regulation of cytoplasmic translational elongation|down-regulation of cytoplasmic translational elongation|inhibition of cytoplasmic translational elongation						vw	2012-04-03T05:07:14Z						biological_process											owl:Class	
GO:0002181	biolink:NamedThing	cytoplasmic translation	The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.	got7fsn_ti					Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms.		hjd	2011-06-09T03:11:53Z						biological_process											owl:Class	
GO:0021543	biolink:NamedThing	pallium development	The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.	got7fsn_ti														biological_process											owl:Class	
GO:0021537	biolink:NamedThing	telencephalon development	The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.	got7fsn_ti	cerebrum development													biological_process											owl:Class	
GO:0035037	biolink:NamedThing	sperm entry	An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur.	got7fsn_ti														biological_process											owl:Class	
GO:0090440	biolink:NamedThing	abscisic acid transmembrane transporter activity	Enables the transfer of abscisic acid from one side of a membrane to the other.	got7fsn_ti	abscisic acid transporter activity						tb	2012-08-20T14:29:42Z						molecular_function											owl:Class	
GO:0080168	biolink:NamedThing	abscisic acid transport	The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore.	got7fsn_ti							dhl	2010-09-23T05:08:56Z						biological_process											owl:Class	
GO:0043194	biolink:NamedThing	axon initial segment	Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.	got7fsn_ti	initial segment											NIF_Subcellular:sao256000789		cellular_component											owl:Class	
GO:0044304	biolink:NamedThing	main axon	The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites.	got7fsn_ti	axon shaft|axon trunk|axonal shaft						jl	2010-02-05T03:48:17Z				NIF_Subcellular:sao1596975044		cellular_component											owl:Class	
GO:0120307	biolink:NamedThing	Hechtian strand	An extended membranous thread which firmly connects the plasma membrane to the cell wall during plasmolysis such that the plasma membrane does not separate from the cell wall completely.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21138					krc	2021-03-19T20:31:15Z				Wikipedia:Hechtian_strand		cellular_component											owl:Class	
GO:0002341	biolink:NamedThing	central B cell anergy	Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.	got7fsn_ti	central B-cell anergy|central B-lymphocyte anergy|central B lymphocyte anergy													biological_process											owl:Class	
GO:0045265	biolink:NamedThing	proton-transporting ATP synthase, stator stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core.	got7fsn_ti	hydrogen-transporting ATP synthase, stator stalk													cellular_component											owl:Class	
GO:0044692	biolink:NamedThing	exoribonuclease activator activity	Binds to and increases the activity of an exoribonuclease.	got7fsn_ti							jl	2012-08-15T15:13:57Z						molecular_function											owl:Class	
GO:0032075	biolink:NamedThing	positive regulation of nuclease activity	Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.	got7fsn_ti	stimulation of nuclease activity|upregulation of nuclease activity|up regulation of nuclease activity|activation of nuclease activity|nuclease activator|up-regulation of nuclease activity													biological_process											owl:Class	
GO:0009920	biolink:NamedThing	cell plate formation involved in plant-type cell wall biogenesis	The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana.	got7fsn_ti	cell plate formation involved in cellulose and pectin-containing cell wall biogenesis													biological_process											owl:Class	
CL:0000066	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005347	biolink:NamedThing	ATP transmembrane transporter activity	Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.	got7fsn_ti											GO:0005348			molecular_function											owl:Class	
GO:0015867	biolink:NamedThing	ATP transport	The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0098651	biolink:NamedThing	basement membrane collagen trimer	Any collagen timer that is part of a basement membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0033009	biolink:NamedThing	nucleomorph	A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively.	got7fsn_ti												Wikipedia:Nucleomorph		cellular_component											owl:Class	
GO:0045467	biolink:NamedThing	R7 cell development	The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.	got7fsn_ti														biological_process											owl:Class	
GO:1990965	biolink:NamedThing	cytosylglucuronate decarboxylase activity	Catalysis of the reaction: cytosylglucuronic acid + H(+) = cytosylarabinopyranose + CO(2).	got7fsn_ti					This enzymatic activity was shown to be involved in the bacterial blasticidin S biosynthetic pathway.		pr	2016-06-09T13:05:27Z						molecular_function											owl:Class	
GO:0080155	biolink:NamedThing	regulation of double fertilization forming a zygote and endosperm	Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.	got7fsn_ti							dhl	2010-09-01T03:46:39Z						biological_process											owl:Class	
GO:0009567	biolink:NamedThing	double fertilization forming a zygote and endosperm	Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.	got7fsn_ti	double fertilization													biological_process											owl:Class	
GO:2001206	biolink:NamedThing	positive regulation of osteoclast development	Any process that activates or increases the frequency, rate or extent of osteoclast development.	got7fsn_ti	positive regulation of osteoclast cell development						yaf	2011-11-10T10:59:12Z						biological_process											owl:Class	
GO:1990850	biolink:NamedThing	H-gal-GP complex	A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.	got7fsn_ti	galactose-containing glycoprotein complex|Haemonchus galactose-containing glycoprotein complex						jl	2015-09-10T16:40:39Z						cellular_component											owl:Class	
GO:0072220	biolink:NamedThing	metanephric descending thin limb development	The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.	got7fsn_ti							mah	2010-03-18T03:35:05Z						biological_process											owl:Class	
GO:0072236	biolink:NamedThing	metanephric loop of Henle development	The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros.	got7fsn_ti	metanephric intermediate tubule development						mah	2010-03-18T03:46:18Z						biological_process											owl:Class	
GO:0002815	biolink:NamedThing	biosynthetic process of antibacterial peptides active against Gram-positive bacteria	The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.	got7fsn_ti														biological_process											owl:Class	
GO:0009505	biolink:NamedThing	plant-type cell wall	A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.	got7fsn_ti	cellulose and pectin-containing cell wall|plant cell wall													cellular_component											owl:Class	
GO:0048854	biolink:NamedThing	brain morphogenesis	The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).	got7fsn_ti														biological_process											owl:Class	
GO:0007420	biolink:NamedThing	brain development	The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).	got7fsn_ti														biological_process											owl:Class	
GO:1901254	biolink:NamedThing	positive regulation of intracellular transport of viral material	Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material.	got7fsn_ti	up-regulation of movement of virus within host cell|positive regulation of viral egress|upregulation of egress of virus within host cell|upregulation of viral egress|up regulation of viral egress|activation of movement of virus within host cell|positive regulation of egress of virus within host cell|up-regulation of viral egress|up regulation of movement of virus within host cell|up regulation of egress of virus within host cell|upregulation of movement of virus within host cell|activation of viral egress|activation of egress of virus within host cell|positive regulation of movement of virus within host cell|up-regulation of egress of virus within host cell						ss	2012-08-09T05:45:54Z						biological_process											owl:Class	
GO:0019058	biolink:NamedThing	viral life cycle	A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.	got7fsn_ti	viral infectious cycle|viral replication|lytic viral life cycle|viral assembly, maturation, egress, and release										GO:0019067			biological_process											owl:Class	
GO:0009545	biolink:NamedThing	elaioplast	A leucoplast in which oil is stored.	got7fsn_ti												Wikipedia:Elaioplast		cellular_component											owl:Class	
GO:0001705	biolink:NamedThing	ectoderm formation	The formation of ectoderm during gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0000745	biolink:NamedThing	nuclear migration involved in conjugation with mutual genetic exchange	The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion.	got7fsn_ti	nuclear exchange during conjugation without cellular fusion|nuclear migration involved in conjugation without cellular fusion													biological_process											owl:Class	
GO:0000744	biolink:NamedThing	karyogamy involved in conjugation with mutual genetic exchange	During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena.	got7fsn_ti	karyogamy involved in conjugation without cellular fusion	https://github.com/geneontology/go-ontology/issues/16248												biological_process											owl:Class	
GO:0072379	biolink:NamedThing	ER membrane insertion complex	A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.	got7fsn_ti	endoplasmic reticulum membrane insertion complex						mah	2010-11-24T02:07:09Z						cellular_component											owl:Class	
GO:0009544	biolink:NamedThing	chloroplast ATP synthase complex	The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts.	got7fsn_ti														cellular_component											owl:Class	
GO:0070263	biolink:NamedThing	external side of fungal-type cell wall	The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents.	got7fsn_ti														cellular_component											owl:Class	
GO:0014817	biolink:NamedThing	skeletal muscle satellite cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0014813	biolink:NamedThing	skeletal muscle satellite cell commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.	got7fsn_ti														biological_process											owl:Class	
GO:0061558	biolink:NamedThing	cranial ganglion maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.	got7fsn_ti	cranial ganglia maturation						dph	2013-07-10T08:59:52Z						biological_process											owl:Class	
GO:2000034	biolink:NamedThing	regulation of seed maturation	Any process that modulates the frequency, rate or extent of seed maturation.	got7fsn_ti							tb	2010-08-05T11:33:33Z						biological_process											owl:Class	
GO:0005662	biolink:NamedThing	DNA replication factor A complex	A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.	got7fsn_ti	RPA|replication protein A											Wikipedia:Replication_protein_A		cellular_component											owl:Class	
GO:0043601	biolink:NamedThing	nuclear replisome	A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0010072	biolink:NamedThing	primary shoot apical meristem specification	The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.	got7fsn_ti	embryo shoot apical meristem specification													biological_process											owl:Class	
GO:0005641	biolink:NamedThing	nuclear envelope lumen	The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.	got7fsn_ti	nuclear intermembrane space|perinuclear space|nuclear membrane lumen				Note that this term should not be confused with the cellular component term 'perinuclear region ; GO:0048471'.						GO:0005653			cellular_component											owl:Class	
GO:1904236	biolink:NamedThing	negative regulation of substrate-dependent cell migration, cell attachment to substrate	Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.	got7fsn_ti	inhibition of substrate-dependent cell migration, cell attachment to substrate|down regulation of substrate-bound cell migration, cell attachment to substrate|down-regulation of substrate-dependent cell migration, cell attachment to substrate|inhibition of substrate-bound cell migration, cell attachment to substrate|down regulation of substrate-dependent cell migration, cell attachment to substrate|down-regulation of substrate-bound cell migration, cell attachment to substrate|downregulation of substrate-bound cell migration, cell attachment to substrate|downregulation of substrate-dependent cell migration, cell attachment to substrate|negative regulation of substrate-bound cell migration, cell attachment to substrate						pga	2015-05-15T13:30:05Z						biological_process											owl:Class	
GO:0060524	biolink:NamedThing	dichotomous subdivision of prostate epithelial cord terminal unit	The process in which a prostate epithelial cord bifurcates at its end.	got7fsn_ti	prostate epithelial cord bifurcation													biological_process											owl:Class	
GO:0060442	biolink:NamedThing	branching involved in prostate gland morphogenesis	The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.	got7fsn_ti	prostate gland branching morphogenesis|prostate branching													biological_process											owl:Class	
GO:0042959	biolink:NamedThing	alkanesulfonate transmembrane transporter activity	Enables the directed movement of alkanesulfonate from one side of a membrane to the other.	got7fsn_ti	alkanesulphonate transporter activity|alkanesulfonate transporter activity													molecular_function											owl:Class	
GO:0042918	biolink:NamedThing	alkanesulfonate transport	The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical.	got7fsn_ti	alkanesulphonate transport													biological_process											owl:Class	
GO:0010299	biolink:NamedThing	detoxification of cobalt ion	Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion.	got7fsn_ti														biological_process											owl:Class	
GO:0005743	biolink:NamedThing	mitochondrial inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.	got7fsn_ti	inner mitochondrial membrane|mitochondrion inner membrane|inner mitochondrion membrane											Wikipedia:Inner_mitochondrial_membrane|NIF_Subcellular:sao1371347282		cellular_component											owl:Class	
GO:1902758	biolink:NamedThing	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process	The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum.	got7fsn_ti	bis(molybdopterin guanine dinucleotide)molybdenum biosynthesis|bis-Mo-molybdopterin-guanine dinucleotide cofactor biosynthetic process|bis(molybdopterin guanine dinucleotide)molybdenum formation|bis(molybdopterin guanine dinucleotide)molybdenum synthesis|bis(molybdopterin guanine dinucleotide)molybdenum anabolism						dph	2014-03-06T13:58:18Z			GO:0061600	MetaCyc:PWY-5964		biological_process											owl:Class	
GO:0061603	biolink:NamedThing	molybdenum cofactor guanylyltransferase activity	Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.	got7fsn_ti							dph	2014-02-10T14:54:36Z				RHEA:34243|EC:2.7.7.77		molecular_function											owl:Class	
GO:0014034	biolink:NamedThing	neural crest cell fate commitment	The process in which a cell becomes committed to become a neural crest cell.	got7fsn_ti														biological_process											owl:Class	
GO:0014029	biolink:NamedThing	neural crest formation	The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.	got7fsn_ti														biological_process											owl:Class	
GO:2000275	biolink:NamedThing	regulation of oxidative phosphorylation uncoupler activity	Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity.	got7fsn_ti	regulation of uncoupling protein activity|regulation of mitochondrial uncoupling protein activity						mah	2010-12-07T12:14:54Z						biological_process											owl:Class	
GO:0050953	biolink:NamedThing	sensory perception of light stimulus	The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti														biological_process											owl:Class	
GO:0120109	biolink:NamedThing	mitotic telomere clustering and tethering at nuclear periphery	The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle.	got7fsn_ti							krc	2017-11-01T18:04:37Z						biological_process											owl:Class	
GO:0036355	biolink:NamedThing	2-iminoacetate synthase activity	Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+.	got7fsn_ti							bf	2012-09-19T14:52:51Z				EC:4.1.99.19|RHEA:26361|MetaCyc:RXN-11319		molecular_function											owl:Class	
GO:0044695	biolink:NamedThing	Dsc E3 ubiquitin ligase complex	An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.	got7fsn_ti							jl	2012-08-16T13:41:48Z						cellular_component											owl:Class	
GO:0031370	biolink:NamedThing	eukaryotic initiation factor 4G binding	Binding to eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation.	got7fsn_ti	eIF4G binding													molecular_function											owl:Class	
GO:0042919	biolink:NamedThing	benzoate transport	The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0000390	biolink:NamedThing	spliceosomal complex disassembly	Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.	got7fsn_ti	U2-type spliceosome disassembly|spliceosome complex disassembly|U12-type spliceosome disassembly|spliceosome disassembly										GO:0000391|GO:0000392			biological_process											owl:Class	
GO:0000398	biolink:NamedThing	mRNA splicing, via spliceosome	The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.	got7fsn_ti	pre-mRNA splicing|mRNA splicing|nuclear mRNA splicing, via spliceosome|splicing GT-AG intron|splicing AT-AC intron|nuclear mRNA splicing via U2-type spliceosome|nuclear mRNA splicing via U12-type spliceosome				Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.						GO:0006374|GO:0006375			biological_process											owl:Class	
GO:0008364	biolink:NamedThing	pupal chitin-based cuticle development	Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster.	got7fsn_ti	pupal cuticle synthesis|pupal cuticle anabolism|pupal cuticle formation													biological_process											owl:Class	
GO:0044725	biolink:NamedThing	chromatin reprogramming in the zygote	The global reprogramming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process.	got7fsn_ti							jl	2012-10-24T13:53:28Z						biological_process											owl:Class	
GO:0038176	biolink:NamedThing	positive regulation of SREBP signaling pathway in response to decreased oxygen levels	Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels.	got7fsn_ti	positive regulation of SREBP-mediated signaling pathway in absence of oxygen|positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels						bf	2012-07-20T01:30:25Z						biological_process											owl:Class	
GO:0034422	biolink:NamedThing	aleurone grain lumen	The volume enclosed by the membrane of an aleurone grain.	got7fsn_ti														cellular_component											owl:Class	
GO:1905299	biolink:NamedThing	negative regulation of intestinal epithelial cell development	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development.	got7fsn_ti	downregulation of intestinal epithelial cell development|down-regulation of intestinal epithelial cell development|inhibition of intestinal epithelial cell development|down regulation of intestinal epithelial cell development						rph	2016-06-30T11:40:55Z						biological_process											owl:Class	
GO:1904020	biolink:NamedThing	regulation of G protein-coupled receptor internalization	Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization.	got7fsn_ti	regulation of G-protein-coupled receptor internalization						pga	2015-03-10T17:10:45Z						biological_process											owl:Class	
GO:1905833	biolink:NamedThing	negative regulation of microtubule nucleation	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation.	got7fsn_ti	downregulation of microtubule nucleation|inhibition of microtubule nucleation|down regulation of microtubule nucleation|down-regulation of microtubule nucleation						hbye	2017-01-17T12:00:56Z						biological_process											owl:Class	
GO:0046785	biolink:NamedThing	microtubule polymerization	The addition of tubulin heterodimers to one or both ends of a microtubule.	got7fsn_ti	microtubule assembly|microtubule formation													biological_process											owl:Class	
GO:0097084	biolink:NamedThing	vascular associated smooth muscle cell development	The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	got7fsn_ti	vascular smooth muscle cell development						pr	2011-06-20T04:03:08Z						biological_process											owl:Class	
GO:0043362	biolink:NamedThing	nucleate erythrocyte maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus.	got7fsn_ti	nucleate red blood cell maturation|nucleate RBC maturation													biological_process											owl:Class	
GO:0048823	biolink:NamedThing	nucleate erythrocyte development	The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti	nucleate RBC development|nucleate red blood cell development													biological_process											owl:Class	
GO:0061363	biolink:NamedThing	negative regulation of progesterone biosynthesis involved in luteolysis	Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis.	got7fsn_ti	functional luteolysis						dph	2010-10-14T03:08:41Z						biological_process											owl:Class	
GO:0006701	biolink:NamedThing	progesterone biosynthetic process	The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.	got7fsn_ti	progesterone biosynthesis|progesterone synthesis|progesterone anabolism|progesterone formation													biological_process											owl:Class	
GO:0035598	biolink:NamedThing	N6-threonylcarbomyladenosine methylthiotransferase activity	Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A).	got7fsn_ti	t6A methylthiotransferase activity						bf	2010-11-12T01:28:32Z				Reactome:R-HSA-6786571		molecular_function											owl:Class	
GO:0035600	biolink:NamedThing	tRNA methylthiolation	The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule.	got7fsn_ti							bf	2010-11-12T01:34:02Z						biological_process											owl:Class	
GO:2000315	biolink:NamedThing	positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.	got7fsn_ti	positive regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation						vk	2011-01-18T10:27:19Z						biological_process											owl:Class	
GO:0070902	biolink:NamedThing	mitochondrial tRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule.	got7fsn_ti							mah	2009-09-02T04:09:48Z						biological_process											owl:Class	
GO:0061984	biolink:NamedThing	catabolite repression	A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources.	got7fsn_ti							dph	2018-02-15T16:34:14Z						biological_process											owl:Class	
GO:0043093	biolink:NamedThing	FtsZ-dependent cytokinesis	A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.	got7fsn_ti	prokaryotic fission|cytokinesis by binary fission|prokaryote-type cytokinesis				Note that this term is intended for the annotation of prokaryotic gene products.							Wikipedia:Binary_fission		biological_process											owl:Class	
GO:0001828	biolink:NamedThing	inner cell mass cellular morphogenesis	The morphogenesis of cells in the inner cell mass.	got7fsn_ti					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.									biological_process											owl:Class	
GO:0010876	biolink:NamedThing	lipid localization	Any process in which a lipid is transported to, or maintained in, a specific location.	got7fsn_ti	lipid localisation													biological_process											owl:Class	
GO:0035800	biolink:NamedThing	deubiquitinase activator activity	Binds to and increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences.	got7fsn_ti								2011-04-18T10:20:15Z						molecular_function											owl:Class	
GO:2000158	biolink:NamedThing	positive regulation of ubiquitin-specific protease activity	Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.	got7fsn_ti	positive regulation of UBP|positive regulation of ubiquitin hydrolase activity|positive regulation of UCH2|positive regulation of deubiquitinase activity						tb	2010-10-04T10:42:29Z						biological_process											owl:Class	
GO:1990658	biolink:NamedThing	transnitrosylase complex	A transferase complex which is capable of transferring nitrogenous groups from one component to another.	got7fsn_ti	transferase complex, transferring nitrogenous groups				An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T11:17:17Z						cellular_component											owl:Class	
GO:2000176	biolink:NamedThing	positive regulation of pro-T cell differentiation	Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.	got7fsn_ti	positive regulation of pro-T lymphocyte differentiation						mah	2010-10-11T10:24:35Z						biological_process											owl:Class	
GO:0032290	biolink:NamedThing	peripheral nervous system myelin formation	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.	got7fsn_ti	myelin formation in peripheral nervous system	https://github.com/geneontology/go-ontology/issues/19106												biological_process											owl:Class	
GO:0050729	biolink:NamedThing	positive regulation of inflammatory response	Any process that activates or increases the frequency, rate or extent of the inflammatory response.	got7fsn_ti	activation of inflammatory response|up regulation of inflammatory response|stimulation of inflammatory response|upregulation of inflammatory response|up-regulation of inflammatory response													biological_process											owl:Class	
GO:0097350	biolink:NamedThing	neutrophil clearance	The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms.	got7fsn_ti							pr	2012-06-27T03:53:38Z						biological_process											owl:Class	
GO:0036062	biolink:NamedThing	presynaptic periactive zone	A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development.	got7fsn_ti	pre-synaptic periactive zone|periactive zone						bf	2011-12-14T02:25:29Z						cellular_component											owl:Class	
GO:0097117	biolink:NamedThing	guanylate kinase-associated protein clustering	The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons.	got7fsn_ti	GKAP clustering						pr	2011-07-31T05:44:35Z						biological_process											owl:Class	
GO:0008065	biolink:NamedThing	establishment of blood-nerve barrier	The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier.	got7fsn_ti	establishment of blood/nerve barrier													biological_process											owl:Class	
GO:0007422	biolink:NamedThing	peripheral nervous system development	The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.	got7fsn_ti														biological_process											owl:Class	
CL:0000166	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000319	biolink:NamedThing	regulation of T-helper 17 cell differentiation	Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation.	got7fsn_ti	regulation of T-helper 17 cell development						mah	2011-01-18T01:43:48Z						biological_process											owl:Class	
GO:0072538	biolink:NamedThing	T-helper 17 type immune response	An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.	got7fsn_ti	Th17 immune response						mah	2011-01-17T11:13:53Z						biological_process											owl:Class	
GO:0033105	biolink:NamedThing	chlorosome envelope	The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome.	got7fsn_ti	chlorosome membrane				Note that the chlorosome envelope is not a single or double lipid bilayer, so this term is not a child of 'organelle membrane ; GO:0031090' or 'organelle envelope ; GO:0031967'.									cellular_component											owl:Class	
NCBITaxon:Union_0000020	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043160	biolink:NamedThing	acrosomal lumen	The volume enclosed within the acrosome membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0001669	biolink:NamedThing	acrosomal vesicle	A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.	got7fsn_ti	acrosomal granule|acrosome											Wikipedia:Acrosome		cellular_component											owl:Class	
GO:1990686	biolink:NamedThing	LDL-containing protein-lipid-RNA complex	A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.	got7fsn_ti					Examples of LDL-containing protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034362 'low-density lipoprotein particle', which describe complexes of proteins and lipids only, without RNAs.		pr	2015-03-11T15:11:34Z						cellular_component											owl:Class	
CHEBI:39026	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071683	biolink:NamedThing	sensory dendrite	A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron.	got7fsn_ti							mah	2010-02-19T04:17:05Z						cellular_component											owl:Class	
CL:0000101	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052547	biolink:NamedThing	regulation of peptidase activity	Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.	got7fsn_ti	peptidase regulator activity													biological_process											owl:Class	
GO:0005826	biolink:NamedThing	actomyosin contractile ring	A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane.  In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.	got7fsn_ti	constriction ring|CAR|contractile actomyosin ring|cytokinetic ring|actomyosin ring										GO:0030480			cellular_component											owl:Class	
GO:0032153	biolink:NamedThing	cell division site	The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.	got7fsn_ti	cell division plane				Note that this term refers to the future site of division in a cell that has not yet divided.									cellular_component											owl:Class	
GO:0061456	biolink:NamedThing	mesenchymal stem cell migration involved in uteric bud morphogenesis	The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti							dph	2012-08-22T17:19:22Z						biological_process											owl:Class	
GO:0060675	biolink:NamedThing	ureteric bud morphogenesis	The process in which the ureteric bud is generated and organized.	got7fsn_ti							dph	2009-06-02T01:31:41Z						biological_process											owl:Class	
GO:0090628	biolink:NamedThing	plant epidermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	got7fsn_ti							tb	2015-02-06T17:32:21Z						biological_process											owl:Class	
GO:0015295	biolink:NamedThing	solute:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in).	got7fsn_ti	heavy metal ion:hydrogen symporter activity|low affinity metal ion uptake transporter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|L-idonate/D-gluconate:hydrogen symporter activity|high affinity metal ion uptake transporter activity|solute:hydrogen symporter activity													molecular_function											owl:Class	
GO:0070470	biolink:NamedThing	plasma membrane respirasome	A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.	got7fsn_ti	plasma membrane electron transport chain|plasma membrane respiratory chain	https://github.com/geneontology/go-ontology/issues/12846												cellular_component											owl:Class	
GO:0030122	biolink:NamedThing	AP-2 adaptor complex	A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).	got7fsn_ti	HA2 clathrin adaptor|HA2													cellular_component											owl:Class	
GO:0030132	biolink:NamedThing	clathrin coat of coated pit	The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0005308	biolink:NamedThing	creatine transmembrane transporter activity	Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.	got7fsn_ti														molecular_function											owl:Class	
GO:0015881	biolink:NamedThing	creatine transmembrane transport	The directed movement of creatine across a membrane.	got7fsn_ti	creatine transport						pr	2013-12-20T11:01:18Z			GO:1902598			biological_process											owl:Class	
GO:0009677	biolink:NamedThing	double fertilization forming two zygotes	Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis.	got7fsn_ti														biological_process											owl:Class	
NCBITaxon:58022	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051395	biolink:NamedThing	negative regulation of nerve growth factor receptor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.	got7fsn_ti	negative regulation of NGF receptor activity|down-regulation of nerve growth factor receptor activity|inhibition of nerve growth factor receptor activity|downregulation of nerve growth factor receptor activity|down regulation of nerve growth factor receptor activity													biological_process											owl:Class	
GO:0009357	biolink:NamedThing	protein-N(PI)-phosphohistidine-sugar phosphotransferase complex	An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system.	got7fsn_ti														cellular_component											owl:Class	
GO:0061122	biolink:NamedThing	positive regulation of positive chemotaxis to cAMP	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.	got7fsn_ti							dph	2010-05-17T08:25:55Z						biological_process											owl:Class	
GO:0043327	biolink:NamedThing	chemotaxis to cAMP	The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.	got7fsn_ti	chemotaxis to 3',5' cAMP|chemotaxis to adenosine 3',5'-cyclophosphate|chemotaxis to cyclic AMP|chemotaxis to 3',5'-cAMP													biological_process											owl:Class	
GO:0051284	biolink:NamedThing	positive regulation of sequestering of calcium ion	Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.	got7fsn_ti	up-regulation of sequestering of calcium ion|stimulation of sequestering of calcium ion|positive regulation of sequestering of calcium ion (Ca2+)|positive regulation of calcium ion (Ca2+) storage|up regulation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) sequestering|positive regulation of sequestration of calcium ion (Ca2+)|positive regulation of calcium ion (Ca2+) retention|positive regulation of retention of calcium ion (Ca2+)|positive regulation of storage of calcium ion (Ca2+)|activation of sequestering of calcium ion|upregulation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) sequestration													biological_process											owl:Class	
GO:0006434	biolink:NamedThing	seryl-tRNA aminoacylation	The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0097056	biolink:NamedThing	selenocysteinyl-tRNA(Sec) biosynthetic process	The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA[Ser]Sec kinase; lastly, selenium is swapped for the phosphate on the serine.	got7fsn_ti	selenocysteinyl-tRNA(Sec) formation|selenocysteinyl-tRNA(Sec) anabolism|selenocysteinyl-tRNA(Sec) biosynthesis|selenocysteinyl-tRNA(Sec) synthesis						pr	2011-05-25T05:33:19Z						biological_process											owl:Class	
GO:0090103	biolink:NamedThing	cochlea morphogenesis	The process in which the cochlea is generated and organized.	got7fsn_ti							tb	2009-11-18T11:45:11Z						biological_process											owl:Class	
GO:0090102	biolink:NamedThing	cochlea development	The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.	got7fsn_ti							tb	2009-11-18T11:42:15Z						biological_process											owl:Class	
GO:0007465	biolink:NamedThing	R7 cell fate commitment	The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium.	got7fsn_ti														biological_process											owl:Class	
GO:0043202	biolink:NamedThing	lysosomal lumen	The volume enclosed within the lysosomal membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0060898	biolink:NamedThing	eye field cell fate commitment involved in camera-type eye formation	The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.	got7fsn_ti							dph	2009-08-13T02:10:58Z						biological_process											owl:Class	
GO:0060897	biolink:NamedThing	neural plate regionalization	The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.	got7fsn_ti							dph	2009-08-13T02:09:04Z						biological_process											owl:Class	
GO:0035703	biolink:NamedThing	monocyte migration into blood stream	The movement of a monocyte from the bone marrow to the blood stream.	got7fsn_ti	release of monocytes into circulation						bf	2011-03-02T11:37:54Z						biological_process											owl:Class	
CL:0000576	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140537	biolink:NamedThing	transcription regulator activator activity	A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16132			Usage guidance: transcription regulator activators bind to a transcription regulator to allow it to reach the chromatin or to contact other transcriptional regulators. This activity does not occur at the promoter. For activities that do occur at the promoter, consider GO:0001216 ; DNA-binding transcription activator activity or GO:0003713; transcription coactivator activity; those activities respectively bind DNA themselves or positively regulate a transcription regulator when it is located at the chromatin.		pg	2020-11-03T14:04:59Z						molecular_function											owl:Class	
GO:0010468	biolink:NamedThing	regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	got7fsn_ti	regulation of protein expression|regulation of gene product expression				This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression.  For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.							Wikipedia:Regulation_of_gene_expression		biological_process											owl:Class	
GO:0097743	biolink:NamedThing	de novo centriole assembly via blepharoplast	A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface.	got7fsn_ti	multiciliation|multiciliogenesis						pr	2016-10-19T15:18:34Z						biological_process											owl:Class	
NCBITaxon:35493	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030155	biolink:NamedThing	regulation of cell adhesion	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.	got7fsn_ti	cell adhesion receptor regulator activity													biological_process											owl:Class	
GO:0001188	biolink:NamedThing	RNA polymerase I preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter.	got7fsn_ti	RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nucleolar primary rRNA transcript|RNA polymerase I transcriptional preinitiation complex assembly|RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript						krc	2011-08-24T04:16:28Z			GO:0001189			biological_process											owl:Class	
GO:0070209	biolink:NamedThing	ASTRA complex	A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p.	got7fsn_ti														cellular_component											owl:Class	
GO:0003193	biolink:NamedThing	pulmonary valve formation	The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti							dph	2009-10-08T01:11:20Z						biological_process											owl:Class	
GO:0003184	biolink:NamedThing	pulmonary valve morphogenesis	The process in which the structure of the pulmonary valve is generated and organized.	got7fsn_ti							dph	2009-10-08T12:03:35Z						biological_process											owl:Class	
GO:1990957	biolink:NamedThing	NPHP complex	A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways.	got7fsn_ti	NPHP module				Although there is some evidence, it's still unclear if the MKS and NPHP complexes are constituent parts of the ciliary Y-shaped links or are simply responsible for aligning and attaching the Y-shaped links to the cilium membrane and axoneme.		pr	2016-06-06T10:59:45Z						cellular_component											owl:Class	
GO:0015651	biolink:NamedThing	quaternary ammonium group transmembrane transporter activity	Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.	got7fsn_ti	quaternary amine transmembrane transporter activity|quaternary ammonium compound transporter activity										GO:0015202			molecular_function											owl:Class	
GO:0015697	biolink:NamedThing	quaternary ammonium group transport	The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.	got7fsn_ti	quaternary amine transport|quaternary ammonium compound transport										GO:0015845			biological_process											owl:Class	
GO:0071019	biolink:NamedThing	U12-type post-mRNA release spliceosomal complex	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.	got7fsn_ti	AT-AC post-mRNA release spliceosomal complex|mammalian U12-type spliceosomal complex I|minor post-mRNA release spliceosomal complex						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0005691	biolink:NamedThing	U6atac snRNP	A ribonucleoprotein complex that contains small nuclear RNA U6atac, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6atac snRNP, most of which remain associated with the U6atac snRNA both while the U6atac snRNP is free or assembled into the U4atac/U6atac snRNP or into a series of spliceosomal complexes.	got7fsn_ti	snRNP U6atac													cellular_component											owl:Class	
GO:0021849	biolink:NamedThing	neuroblast division in subventricular zone	The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.	got7fsn_ti														biological_process											owl:Class	
GO:0060285	biolink:NamedThing	cilium-dependent cell motility	Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.	got7fsn_ti	ciliary cell motility|cilium cell motility|microtubule-based flagellar cell motility				Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent.						GO:0071974			biological_process											owl:Class	
GO:0120020	biolink:NamedThing	cholesterol transfer activity	Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	cholesterol carrier activity|intermembrane cholesterol transfer activity|cholesterol transporter activity	https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-17T04:46:12Z			GO:0017127	Reactome:R-HSA-266082|Reactome:R-HSA-8951850|Reactome:R-HSA-5682111|Reactome:R-HSA-1454928|Reactome:R-HSA-216723|Reactome:R-HSA-265443|Reactome:R-HSA-265545		molecular_function											owl:Class	
GO:0015918	biolink:NamedThing	sterol transport	The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0019812	biolink:NamedThing	type I site-specific deoxyribonuclease complex	A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell.	got7fsn_ti	type I restriction enzyme complex													cellular_component											owl:Class	
GO:0072062	biolink:NamedThing	proximal convoluted tubule segment 1 cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.	got7fsn_ti	S1 cell differentiation						mah	2010-01-25T04:11:17Z						biological_process											owl:Class	
GO:0072031	biolink:NamedThing	proximal convoluted tubule segment 1 development	The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.	got7fsn_ti	S1 development						mah	2010-01-25T02:55:57Z						biological_process											owl:Class	
GO:0002142	biolink:NamedThing	stereocilia ankle link complex	A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin.	got7fsn_ti							hjd	2009-05-06T10:33:57Z						cellular_component											owl:Class	
GO:0002141	biolink:NamedThing	stereocilia ankle link	A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia.	got7fsn_ti							hjd	2009-05-06T10:31:56Z						cellular_component											owl:Class	
GO:0086004	biolink:NamedThing	regulation of cardiac muscle cell contraction	Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.	got7fsn_ti							tb	2011-11-10T07:49:10Z						biological_process											owl:Class	
GO:1902940	biolink:NamedThing	positive regulation of intracellular calcium activated chloride channel activity	Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity.	got7fsn_ti	up regulation of intracellular calcium activated chloride channel activity|activation of intracellular calcium activated chloride channel activity|up-regulation of intracellular calcium activated chloride channel activity|upregulation of intracellular calcium activated chloride channel activity						als	2014-04-28T08:49:20Z						biological_process											owl:Class	
GO:0098661	biolink:NamedThing	inorganic anion transmembrane transport	The process in which an inorganic anion is transported across a membrane.	got7fsn_ti	transmembrane inorganic anion transport|inorganic anion membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:0035658	biolink:NamedThing	Mon1-Ccz1 complex	A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p.	got7fsn_ti							bf	2011-01-28T11:31:20Z						cellular_component											owl:Class	
GO:0097416	biolink:NamedThing	Lewy body-like hyaline inclusion	Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments.	got7fsn_ti	LBHI						pr	2012-11-06T16:46:15Z				NIF_Subcellular:nlx_subcell_20090105		cellular_component											owl:Class	
CL:0000540	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000025	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061605	biolink:NamedThing	molybdopterin-synthase adenylyltransferase activity	Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP.	got7fsn_ti							dph	2014-02-11T12:01:32Z				EC:2.7.7.80|RHEA:43616		molecular_function											owl:Class	
GO:0019045	biolink:NamedThing	latent virus replication	Any process required for latent viral replication in a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0019042	biolink:NamedThing	viral latency	The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate.	got7fsn_ti	viral dormancy|latent virus infection|phage lysogeny										GO:0075710|GO:0030069			biological_process											owl:Class	
GO:0072371	biolink:NamedThing	histone kinase activity (H2A-S121 specific)	Catalysis of the transfer of a phosphate group to the serine-121 residue of the N-terminal tail of histone H2A.	got7fsn_ti	histone-serine kinase activity (H2A-S121 specific)|histone serine kinase activity (H2A-S121 specific)						mah	2010-11-16T03:42:59Z						molecular_function											owl:Class	
GO:0072370	biolink:NamedThing	histone H2A-S121 phosphorylation	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 121 of the histone.	got7fsn_ti	histone H2AS121 phosphorylation|histone H2A phosphorylation at S121						mah	2010-11-16T03:42:52Z						biological_process											owl:Class	
GO:0045271	biolink:NamedThing	respiratory chain complex I	Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.	got7fsn_ti	NADH dehydrogenase complex (ubiquinone)|NADH dehydrogenase (ubiquinone) complex|electron transport complex I|NADH-Q oxidoreductase complex				Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (ubiquinone) activity ; GO:0008137'.						GO:0045279			cellular_component											owl:Class	
GO:0015231	biolink:NamedThing	5-formyltetrahydrofolate transmembrane transporter activity	Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other.	got7fsn_ti	5-formyltetrahydrofolate transporter activity													molecular_function											owl:Class	
GO:0015885	biolink:NamedThing	5-formyltetrahydrofolate transport	The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0015137	biolink:NamedThing	citrate transmembrane transporter activity	Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other.	got7fsn_ti	tricarboxylate transport protein											Reactome:R-HSA-433104|TC:2.A.29.7.2		molecular_function											owl:Class	
GO:0015746	biolink:NamedThing	citrate transport	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1990675	biolink:NamedThing	Golgi medial cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex.	got7fsn_ti	medial-Golgi cisterna membrane						bhm	2015-03-02T11:50:29Z						cellular_component											owl:Class	
GO:0005797	biolink:NamedThing	Golgi medial cisterna	The middle Golgi cisterna (or cisternae).	got7fsn_ti														cellular_component											owl:Class	
GO:0010063	biolink:NamedThing	positive regulation of trichoblast fate specification	Any process that induces or promotes trichoblast fate specification.	got7fsn_ti	up regulation of trichoblast fate|upregulation of trichoblast fate|stimulation of trichoblast fate|activation of trichoblast fate|up-regulation of trichoblast fate													biological_process											owl:Class	
GO:0006412	biolink:NamedThing	translation	The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.	got7fsn_ti	protein biosynthetic process|protein anabolism|protein formation|protein synthesis|protein translation|protein biosynthesis										GO:0043037|GO:0006416|GO:0006453	Wikipedia:Translation_(genetics)		biological_process											owl:Class	
GO:0045755	biolink:NamedThing	negative regulation of initiation of acetate catabolic process by acetate	Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.	got7fsn_ti	downregulation of initiation of acetate catabolic process by acetate|negative regulation of initiation of acetate breakdown by acetate|down regulation of initiation of acetate catabolic process by acetate|inhibition of initiation of acetate catabolic process by acetate|down-regulation of initiation of acetate catabolic process by acetate|negative regulation of initiation of acetate degradation by acetate													biological_process											owl:Class	
GO:0062074	biolink:NamedThing	pollen aperture	An area where exine is reduced or absent, in the pollen wall.	got7fsn_ti							dph	2018-09-19T19:19:58Z						cellular_component											owl:Class	
GO:0021684	biolink:NamedThing	cerebellar granular layer formation	The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	got7fsn_ti														biological_process											owl:Class	
NCBITaxon:Union_0000031	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904625	biolink:NamedThing	negative regulation of glycine secretion, neurotransmission	Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission.	got7fsn_ti	down-regulation of glycine secretion, neurotransmission|downregulation of glycine secretion, neurotransmission|inhibition of glycine secretion, neurotransmission|down regulation of glycine secretion, neurotransmission						hjd	2015-08-27T20:03:44Z						biological_process											owl:Class	
GO:1905937	biolink:NamedThing	negative regulation of germ cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation.	got7fsn_ti	down-regulation of germ cell proliferation|down regulation of germ cell proliferation|inhibition of germ cell proliferation|downregulation of germ cell proliferation						hbye	2017-02-09T14:51:41Z						biological_process											owl:Class	
GO:0016282	biolink:NamedThing	eukaryotic 43S preinitiation complex	A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.	got7fsn_ti	eukaryotic 43S pre-initiation complex													cellular_component											owl:Class	
GO:0060017	biolink:NamedThing	parathyroid gland development	The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.	got7fsn_ti														biological_process											owl:Class	
GO:0097047	biolink:NamedThing	DNA replication termination region	A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks.	got7fsn_ti	TER						pr	2011-05-03T03:38:40Z						cellular_component											owl:Class	
GO:0010330	biolink:NamedThing	cellulose synthase complex	A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall.	got7fsn_ti	CESA complex													cellular_component											owl:Class	
GO:0042640	biolink:NamedThing	anagen	The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair.	got7fsn_ti	hair growth				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0043599	biolink:NamedThing	nuclear DNA replication factor C complex	A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species.	got7fsn_ti	nuclear RFC													cellular_component											owl:Class	
GO:0038155	biolink:NamedThing	interleukin-23-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-23 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-23-mediated signaling pathway|interleukin-23-mediated signalling pathway						bf	2012-05-11T11:49:56Z						biological_process											owl:Class	
GO:0071140	biolink:NamedThing	resolution of mitotic recombination intermediates	The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged.	got7fsn_ti							mah	2009-11-16T12:06:05Z						biological_process											owl:Class	
GO:0006312	biolink:NamedThing	mitotic recombination	The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles.	got7fsn_ti												Wikipedia:Mitotic_crossover		biological_process											owl:Class	
GO:0110067	biolink:NamedThing	ammonium transmembrane transporter complex	High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other.	got7fsn_ti	AMT1 complex						kmv	2017-11-20T15:21:10Z						cellular_component											owl:Class	
GO:0032178	biolink:NamedThing	medial membrane band	A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum.	got7fsn_ti	sterol-rich membrane band													cellular_component											owl:Class	
GO:0048657	biolink:NamedThing	anther wall tapetum cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.	got7fsn_ti	tapetal cell differentiation													biological_process											owl:Class	
GO:0048656	biolink:NamedThing	anther wall tapetum formation	The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.	got7fsn_ti	tapetal layer formation|tapetum formation													biological_process											owl:Class	
GO:0002499	biolink:NamedThing	proteolysis within endosome associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.	got7fsn_ti	endosomal proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0035804	biolink:NamedThing	structural constituent of egg coat	The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.	got7fsn_ti	structural constituent of vitelline envelope|structural constituent of zona pellucida						bf	2011-04-19T01:56:06Z						molecular_function											owl:Class	
GO:0010706	biolink:NamedThing	ganglioside biosynthetic process via lactosylceramide	The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.	got7fsn_ti	ganglioside biosynthesis via lactosylceramide biosynthesis|lactosylceramide biosynthesis leading to ganglioside|biosynthesis of lactosylceramide precursor to ganglioside|lactosylceramide biosynthetic process leading to ganglioside													biological_process											owl:Class	
GO:0001572	biolink:NamedThing	lactosylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.	got7fsn_ti	lactosylceramide formation|lactosylceramide synthesis|lactosylceramide anabolism|lactosylceramide biosynthesis													biological_process											owl:Class	
GO:0031911	biolink:NamedThing	cytoproct	Stable, specialized structure for extrusion of waste by the cell into the surrounding medium.	got7fsn_ti														cellular_component											owl:Class	
GO:0010110	biolink:NamedThing	regulation of photosynthesis, dark reaction	Any process that modulates the frequency, rate or extent of photosynthesis dark reaction.	got7fsn_ti														biological_process											owl:Class	
GO:0004994	biolink:NamedThing	somatostatin receptor activity	Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28).	got7fsn_ti	SST receptor activity|SRIF receptor activity|GHIH receptor activity|growth hormone-inhibiting hormone receptor activity|somatotrophin release inhibiting factor receptor activity													molecular_function											owl:Class	
GO:0072025	biolink:NamedThing	distal convoluted tubule development	The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.	got7fsn_ti							mah	2010-01-25T02:40:45Z						biological_process											owl:Class	
GO:0140246	biolink:NamedThing	protein catabolic process at synapse	The chemical reactions and pathways resulting in the breakdown of a protein at a synapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/210			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:12:51Z						biological_process											owl:Class	
GO:0045269	biolink:NamedThing	proton-transporting ATP synthase, central stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis.	got7fsn_ti	hydrogen-transporting ATP synthase, central stalk													cellular_component											owl:Class	
GO:0030168	biolink:NamedThing	platelet activation	A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.	got7fsn_ti	blood coagulation, platelet activation													biological_process											owl:Class	
GO:0001055	biolink:NamedThing	RNA polymerase II activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter						krc	2010-09-23T03:44:23Z				Reactome:R-HSA-6814549|Reactome:R-HSA-6814559		molecular_function											owl:Class	
GO:0015489	biolink:NamedThing	putrescine transmembrane transporter activity	Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.	got7fsn_ti														molecular_function											owl:Class	
GO:0015847	biolink:NamedThing	putrescine transport	The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.	got7fsn_ti														biological_process											owl:Class	
GO:0050970	biolink:NamedThing	detection of electrical stimulus involved in magnetoreception	The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field.	got7fsn_ti	magnetoreception, sensory detection of electrical stimulus|magnetoreception, detection of electrical stimulus|sensory transduction of electrical stimulus during magnetoreception|magnetoception, sensory transduction of electrical stimulus|magnetoreception, sensory transduction of electrical stimulus|sensory detection of electrical stimulus during magnetoreception|detection of electrical stimulus during magnetoreception													biological_process											owl:Class	
GO:0034994	biolink:NamedThing	microtubule organizing center attachment site organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches.	got7fsn_ti	MTOC attachment site organization|MAS organization|microtubule organising centre attachment site organisation													biological_process											owl:Class	
GO:0048137	biolink:NamedThing	spermatocyte division	The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.	got7fsn_ti	spermatocyte cell division													biological_process											owl:Class	
GO:0042777	biolink:NamedThing	plasma membrane ATP synthesis coupled proton transport	The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.	got7fsn_ti	ATP synthesis coupled proton transport													biological_process											owl:Class	
GO:0060847	biolink:NamedThing	endothelial cell fate specification	The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	got7fsn_ti							dph	2009-08-12T11:00:04Z						biological_process											owl:Class	
GO:0060839	biolink:NamedThing	endothelial cell fate commitment	The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell.	got7fsn_ti							dph	2009-08-11T03:52:53Z						biological_process											owl:Class	
GO:0097541	biolink:NamedThing	axonemal basal plate	Part of the axoneme consisting of a highly electron-dense region at the distal end of the ciliary transition zone within the axonemal lumen at which the axonemal central pair of microtubules is connected to the rest of the axonemal structure.	got7fsn_ti	axoneme basal plate|basal plate						pr	2013-12-12T11:10:39Z						cellular_component											owl:Class	
GO:0060659	biolink:NamedThing	nipple sheath formation	The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.	got7fsn_ti							dph	2009-05-29T10:48:39Z						biological_process											owl:Class	
GO:1990325	biolink:NamedThing	collagen type XXVII trimer	A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone.	got7fsn_ti							bhm	2014-03-16T23:13:15Z						cellular_component											owl:Class	
GO:0007432	biolink:NamedThing	salivary gland boundary specification	Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.	got7fsn_ti	salivary gland determination													biological_process											owl:Class	
GO:0007431	biolink:NamedThing	salivary gland development	The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.	got7fsn_ti														biological_process											owl:Class	
GO:0055038	biolink:NamedThing	recycling endosome membrane	The lipid bilayer surrounding a recycling endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0055037	biolink:NamedThing	recycling endosome	An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.	got7fsn_ti	endosomal recycling compartment|ERC|endosome recycling compartment													cellular_component											owl:Class	
GO:0015988	biolink:NamedThing	energy coupled proton transmembrane transport, against electrochemical gradient	The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport.	got7fsn_ti														biological_process											owl:Class	
CHEBI:24636	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070920	biolink:NamedThing	regulation of production of small RNA involved in gene silencing by RNA	Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA.	got7fsn_ti	regulation of gene silencing by RNA, production of guide RNA|regulation of gene silencing by RNA, production of small RNA						mah	2009-09-11T03:41:59Z						biological_process											owl:Class	
GO:0018989	biolink:NamedThing	apolysis	The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.	got7fsn_ti												Wikipedia:Apolysis		biological_process											owl:Class	
GO:1903774	biolink:NamedThing	positive regulation of viral budding via host ESCRT complex	Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex.	got7fsn_ti	positive regulation of viral budding through the ESCRT machinery|upregulation of viral budding through the ESCRT machinery|up-regulation of viral budding through the ESCRT machinery|up regulation of viral budding through the ESCRT machinery|up regulation of viral budding via host ESCRT complex|upregulation of viral budding via host ESCRT complex|activation of viral budding through the ESCRT machinery|activation of viral budding via host ESCRT complex|up-regulation of viral budding via host ESCRT complex						als	2015-01-06T16:21:02Z						biological_process											owl:Class	
GO:1990220	biolink:NamedThing	GroEL-GroES complex	Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins.	got7fsn_ti	bacterial chaperonin complex|bacterial chaperonin ATPase complex						bhm	2013-10-11T09:20:01Z						cellular_component											owl:Class	
GO:1900245	biolink:NamedThing	positive regulation of MDA-5 signaling pathway	Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway.	got7fsn_ti	activation of melanoma differentiation-associated gene 5 signaling pathway|positive regulation of MDA-5 signalling pathway|up-regulation of IFIH1 signaling pathway|up regulation of IFIH1 signaling pathway|upregulation of IFIH1 signaling pathway|up-regulation of MDA5 signaling pathway|positive regulation of IFIH1 signaling pathway|up-regulation of MDA-5 signaling pathway|up regulation of MDA-5 signaling pathway|up-regulation of melanoma differentiation-associated gene 5 signaling pathway|positive regulation of MDA5 signaling pathway|upregulation of MDA5 signaling pathway|activation of MDA5 signaling pathway|up regulation of MDA5 signaling pathway|activation of MDA-5 signaling pathway|activation of IFIH1 signaling pathway|positive regulation of melanoma differentiation-associated gene 5 signaling pathway|upregulation of melanoma differentiation-associated gene 5 signaling pathway|up regulation of melanoma differentiation-associated gene 5 signaling pathway|upregulation of MDA-5 signaling pathway						ss	2012-04-02T10:55:38Z						biological_process											owl:Class	
GO:0048392	biolink:NamedThing	intermediate mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.	got7fsn_ti	intermediate mesoderm cell differentiation													biological_process											owl:Class	
GO:0061823	biolink:NamedThing	ring centriole	A ring-like structure observed at the base of the ciliary cap of insect spermatids. This structure may anchor the axoneme to the ciliary cap membrane and/or act as a diffusion barrier, proposed to be analogous to the annulus of mammalian sperm flagellum.	got7fsn_ti							dph	2017-01-14T14:18:29Z						cellular_component											owl:Class	
GO:0000089	biolink:NamedThing	mitotic metaphase	The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0000087	biolink:NamedThing	mitotic M phase	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.	got7fsn_ti	M-phase of mitotic cell cycle|M phase of mitotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0120124	biolink:NamedThing	membrane fusion priming complex	A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes.	got7fsn_ti	GATE-16 complex|LMA1 complex						krc	2018-02-06T22:22:47Z						cellular_component											owl:Class	
GO:0042144	biolink:NamedThing	vacuole fusion, non-autophagic	The fusion of two vacuole membranes to form a single vacuole.	got7fsn_ti	homotypic vacuole fusion (non-autophagic)|homotypic vacuole fusion|vacuole fusion (non-autophagic)|homotypic vacuole fusion, non-autophagic										GO:0042145			biological_process											owl:Class	
GO:0034400	biolink:NamedThing	gerontoplast	A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence.	got7fsn_ti														cellular_component											owl:Class	
GO:0005833	biolink:NamedThing	hemoglobin complex	An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group.	got7fsn_ti	haemoglobin complex													cellular_component											owl:Class	
GO:1902964	biolink:NamedThing	positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.	got7fsn_ti	positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|activation of metalloendoprotease activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|up regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up-regulation of metalloendopeptidase activity involved in APP catabolic process|positive regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|up regulation of metalloendoprotease activity involved in APP catabolic process|activation of metalloendopeptidase activity involved in APP catabolic process|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|activation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|activation of metalloendoprotease activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoprotease activity involved in APP catabolic process|upregulation of metalloendoprotease activity involved in APP catabolic process|up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoproteinase activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|up regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|up-regulation of metalloendopeptidase activity involved in APP catabolism|up-regulation of metalloendoprotease activity involved in APP catabolism|positive regulation of metalloendoproteinase activity involved in APP catabolic process|positive regulation of metalloendoprotease activity involved in APP catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoproteinase activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendopeptidase activity involved in APP catabolism|up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoprotease activity involved in APP catabolism|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|activation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|activation of metalloendopeptidase activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|upregulation of metalloendopeptidase activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|upregulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|activation of metalloendoprotease activity involved in amyloid precursor protein degradation|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|upregulation of metalloendopeptidase activity involved in APP catabolic process|positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|up-regulation of metalloendoproteinase activity involved in APP catabolism|up regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|activation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up regulation of metalloendopeptidase activity involved in APP catabolism|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|activation of metalloendoproteinase activity involved in amyloid precursor protein degradation|positive regulation of metalloendoprotease activity involved in APP catabolic process|upregulation of metalloendoproteinase activity involved in APP catabolism|activation of metalloendoprotease activity involved in APP catabolic process|up regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|activation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|up regulation of metalloendopeptidase activity involved in APP catabolic process|up regulation of metalloendoproteinase activity involved in APP catabolic process|up-regulation of metalloendoproteinase activity involved in APP catabolic process|positive regulation of metalloendopeptidase activity involved in APP catabolic process|upregulation of metalloendoprotease activity involved in APP catabolism|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|upregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|activation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|activation of metalloendoproteinase activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in APP catabolism						sjp	2014-05-06T09:12:11Z						biological_process											owl:Class	
GO:0042987	biolink:NamedThing	amyloid precursor protein catabolic process	The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.	got7fsn_ti	amyloid precursor protein catabolism|APP catabolic process|amyloid precursor protein degradation|amyloid precursor protein breakdown|APP catabolism													biological_process											owl:Class	
GO:0032784	biolink:NamedThing	regulation of DNA-templated transcription, elongation	Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.	got7fsn_ti	transcription elongation regulator activity|regulation of RNA elongation|regulation of DNA-dependent transcription, elongation|regulation of transcriptional elongation|regulation of transcription elongation, DNA-dependent													biological_process											owl:Class	
GO:0032450	biolink:NamedThing	maltose alpha-glucosidase activity	Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose.	got7fsn_ti	maltase activity											EC:3.2.1.20|MetaCyc:RXN-2141		molecular_function											owl:Class	
GO:0000023	biolink:NamedThing	maltose metabolic process	The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.	got7fsn_ti	malt sugar metabolism|maltose metabolism|malt sugar metabolic process													biological_process											owl:Class	
GO:0120099	biolink:NamedThing	procentriole replication complex	A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates.	got7fsn_ti							krc	2017-09-28T21:41:34Z						cellular_component											owl:Class	
GO:1990674	biolink:NamedThing	Golgi cis cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex.	got7fsn_ti	cis-Golgi cisterna membrane						bhm	2015-03-02T11:48:00Z						cellular_component											owl:Class	
GO:0031095	biolink:NamedThing	platelet dense tubular network membrane	The lipid bilayer surrounding the platelet dense tubular network.	got7fsn_ti														cellular_component											owl:Class	
GO:0090393	biolink:NamedThing	sepal giant cell development	The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti	sepal giant cell formation						tb	2010-12-14T04:44:34Z						biological_process											owl:Class	
GO:0090392	biolink:NamedThing	sepal giant cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C.	got7fsn_ti							tb	2010-12-14T04:38:06Z						biological_process											owl:Class	
GO:0005337	biolink:NamedThing	nucleoside transmembrane transporter activity	Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.	got7fsn_ti	intracellular nucleoside transmembrane transporter activity											Reactome:R-HSA-109536|Reactome:R-HSA-109527|Reactome:R-HSA-109534|Reactome:R-HSA-5628807|RHEA:27318|Reactome:R-HSA-109529|Reactome:R-HSA-727768|Reactome:R-HSA-727767|Reactome:R-HSA-727749|Reactome:R-HSA-727740		molecular_function											owl:Class	
GO:1901642	biolink:NamedThing	nucleoside transmembrane transport	The directed movement of nucleoside across a membrane.	got7fsn_ti	nucleoside membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		pr	2012-11-16T13:32:01Z						biological_process											owl:Class	
GO:0047145	biolink:NamedThing	demethylsterigmatocystin 6-O-methyltransferase activity	Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine.	got7fsn_ti	S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase activity|O-methyltransferase I|demethylsterigmatocystin methyltransferase activity											RHEA:11504|EC:2.1.1.109|MetaCyc:2.1.1.109-RXN		molecular_function											owl:Class	
GO:0097595	biolink:NamedThing	ventral disc crossbridge	Structure horizontally linking adjacent microribbons of the ventral disc in Giardia species (trophozoite stage). The composition of crossbridges is not fully known yet.	got7fsn_ti	ventral disk crossbridge|crossbridge				Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:23:33Z						cellular_component											owl:Class	
GO:0009842	biolink:NamedThing	cyanelle	A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid.	got7fsn_ti	muroplast|cyanoplast													cellular_component											owl:Class	
GO:0044306	biolink:NamedThing	neuron projection terminus	The specialized, terminal region of a neuron projection such as an axon or a dendrite.	got7fsn_ti	neuron projection terminal|nerve terminal|neuron terminal specialization						jl	2010-02-05T02:44:04Z						cellular_component											owl:Class	
GO:0030902	biolink:NamedThing	hindbrain development	The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).	got7fsn_ti	rhombencephalon development													biological_process											owl:Class	
GO:0009515	biolink:NamedThing	granal stacked thylakoid	Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II.	got7fsn_ti	chloroplast stacked thylakoid													cellular_component											owl:Class	
GO:0034592	biolink:NamedThing	synaptic vesicle lumen	The volume enclosed by the synaptic vesicle membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0098028	biolink:NamedThing	virus tail, shaft	The tube of the non-contractile tails of some viruses.	got7fsn_ti	bacteriophage tail shaft				This term applies in particular to the Siphoviridae bacteriophages, where the shaft is the channel for DNA translocation into the host cytoplasm.		bm	2012-07-19T14:24:28Z						cellular_component											owl:Class	
GO:0035271	biolink:NamedThing	ring gland development	Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones.	got7fsn_ti					See also the fly_anatomy.ontology terms 'ring gland ; FBbt:00001722, 'prothoracic gland ; FBbt:00001724', 'corpus allatum ; FBbt:00005800' and 'corpus cardiacum ; FBbt:00005799.									biological_process											owl:Class	
GO:0032068	biolink:NamedThing	type IV site-specific deoxyribonuclease complex	A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation.	got7fsn_ti	type IV restriction enzyme complex													cellular_component											owl:Class	
GO:1905661	biolink:NamedThing	regulation of telomerase RNA reverse transcriptase activity	Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity.	got7fsn_ti	regulation of telomerase, catalyst						nc	2016-11-09T16:55:20Z						biological_process											owl:Class	
GO:0003720	biolink:NamedThing	telomerase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.	got7fsn_ti												Reactome:R-HSA-163090|Reactome:R-HSA-164617		molecular_function											owl:Class	
GO:0000919	biolink:NamedThing	cell plate assembly	The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast.	got7fsn_ti	cell plate formation													biological_process											owl:Class	
GO:0000911	biolink:NamedThing	cytokinesis by cell plate formation	The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana.	got7fsn_ti														biological_process											owl:Class	
GO:0098700	biolink:NamedThing	neurotransmitter loading into synaptic vesicle	The active transport of neurotransmitters into a synaptic vesicle.  This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps.	got7fsn_ti	synaptic vesicle neurotransmitter loading|neurotransmitter uptake into synaptic vesicle|neurotransmitter import into synaptic vesicle													biological_process											owl:Class	
GO:1990691	biolink:NamedThing	cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane	The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport.	got7fsn_ti	cis-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane						bhm	2015-03-12T09:51:01Z						biological_process											owl:Class	
GO:0048219	biolink:NamedThing	inter-Golgi cisterna vesicle-mediated transport	The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.	got7fsn_ti	inter-Golgi cisterna transport													biological_process											owl:Class	
GO:0072493	biolink:NamedThing	host cell endosome lumen	The volume enclosed by the membranes of the host cell endosome.	got7fsn_ti	host endosome lumen						mah	2010-12-15T11:45:53Z						cellular_component											owl:Class	
GO:0003328	biolink:NamedThing	pancreatic D cell fate commitment	The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin.	got7fsn_ti							dph	2009-11-02T08:33:36Z						biological_process											owl:Class	
GO:0003311	biolink:NamedThing	pancreatic D cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.	got7fsn_ti	pancreatic delta cell differentiation						dph	2009-10-26T09:30:27Z						biological_process											owl:Class	
GO:0000712	biolink:NamedThing	resolution of meiotic recombination intermediates	The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.	got7fsn_ti	resolution of meiotic joint molecules as recombinants													biological_process											owl:Class	
GO:2000635	biolink:NamedThing	negative regulation of primary miRNA processing	Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing.	got7fsn_ti	negative regulation of primary microRNA processing|negative regulation of pri-miRNA processing						dph	2011-04-18T03:50:53Z						biological_process											owl:Class	
GO:0072239	biolink:NamedThing	metanephric glomerulus vasculature development	The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.	got7fsn_ti	glomerulus capillary development						mah	2010-03-18T03:50:29Z						biological_process											owl:Class	
GO:0072224	biolink:NamedThing	metanephric glomerulus development	The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.	got7fsn_ti	metanephric glomerular development						mah	2010-03-18T03:36:20Z						biological_process											owl:Class	
GO:0005304	biolink:NamedThing	L-valine transmembrane transporter activity	Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid.	got7fsn_ti	valine/tyrosine/tryptophan permease activity|leucine/valine/isoleucine permease activity|L-valine transporter activity|leucine/isoleucine/valine porter activity|isoleucine/valine:sodium symporter activity													molecular_function											owl:Class	
GO:1903785	biolink:NamedThing	L-valine transmembrane transport	The directed movement of L-valine across a membrane.	got7fsn_ti							al	2015-01-08T14:50:32Z						biological_process											owl:Class	
GO:1901203	biolink:NamedThing	positive regulation of extracellular matrix assembly	Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.	got7fsn_ti	activation of extracellular matrix assembly|up regulation of extracellular matrix assembly|upregulation of extracellular matrix assembly|up-regulation of extracellular matrix assembly						rl	2012-07-27T04:04:32Z						biological_process											owl:Class	
GO:0002492	biolink:NamedThing	peptide antigen assembly with MHC class Ib protein complex	The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	got7fsn_ti														biological_process											owl:Class	
GO:0002398	biolink:NamedThing	MHC class Ib protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0042012	biolink:NamedThing	interleukin-16 receptor activity	Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-16R|IL-16 receptor activity													molecular_function											owl:Class	
GO:0042011	biolink:NamedThing	interleukin-16 binding	Binding to interleukin-16.	got7fsn_ti	IL-16 binding													molecular_function											owl:Class	
GO:0042921	biolink:NamedThing	glucocorticoid receptor signaling pathway	Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor.	got7fsn_ti	glucocorticoid receptor signalling pathway													biological_process											owl:Class	
GO:0007470	biolink:NamedThing	prothoracic disc morphogenesis	The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle.	got7fsn_ti	prothoracic disc metamorphosis													biological_process											owl:Class	
GO:1903730	biolink:NamedThing	regulation of phosphatidate phosphatase activity	Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity.	got7fsn_ti	regulation of phosphatidic acid phosphatase activity|regulation of 3-sn-phosphatidate phosphohydrolase activity|regulation of acid phosphatidyl phosphatase activity|regulation of phosphatic acid phosphatase activity|regulation of phosphatidate phosphohydrolase activity|regulation of phosphatic acid phosphohydrolase activity				Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity		rn	2014-12-11T21:29:55Z						biological_process											owl:Class	
GO:0010866	biolink:NamedThing	regulation of triglyceride biosynthetic process	Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.	got7fsn_ti	regulation of triacylglycerol biosynthetic process													biological_process											owl:Class	
GO:0048528	biolink:NamedThing	post-embryonic root development	The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0043309	biolink:NamedThing	regulation of eosinophil degranulation	Any process that modulates the frequency, rate, or extent of eosinophil degranulation.	got7fsn_ti	regulation of eosinophil granule exocytosis													biological_process											owl:Class	
GO:0061524	biolink:NamedThing	central canal development	The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.	got7fsn_ti							dph	2013-04-20T08:18:31Z						biological_process											owl:Class	
GO:0021510	biolink:NamedThing	spinal cord development	The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0043985	biolink:NamedThing	histone H4-R3 methylation	The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone.	got7fsn_ti	histone H4 R3 methylation|histone H4 methylation at R3|histone H4R3me													biological_process											owl:Class	
GO:0007472	biolink:NamedThing	wing disc morphogenesis	The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.	got7fsn_ti	wing disc metamorphosis													biological_process											owl:Class	
GO:0070622	biolink:NamedThing	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.	got7fsn_ti	UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase complex|N-acetylglucosamine-1-phosphotransferase complex						mah	2009-04-29T04:50:35Z						cellular_component											owl:Class	
GO:0006120	biolink:NamedThing	mitochondrial electron transport, NADH to ubiquinone	The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation.	got7fsn_ti	oxidative phosphorylation, NADH to ubiquinone|complex I (NADH to ubiquinone)													biological_process											owl:Class	
GO:0042775	biolink:NamedThing	mitochondrial ATP synthesis coupled electron transport	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane.	got7fsn_ti	mitochondrial electron transport|organelle ATP synthesis coupled electron transport													biological_process											owl:Class	
GO:0060672	biolink:NamedThing	epithelial cell morphogenesis involved in placental branching	The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta.	got7fsn_ti							dph	2009-06-02T12:44:52Z						biological_process											owl:Class	
GO:0060671	biolink:NamedThing	epithelial cell differentiation involved in embryonic placenta development	The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.	got7fsn_ti							dph	2009-06-02T11:40:52Z						biological_process											owl:Class	
GO:0016502	biolink:NamedThing	nucleotide receptor activity	Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:1900095	biolink:NamedThing	regulation of dosage compensation by inactivation of X chromosome	Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.	got7fsn_ti	regulation of Barr body formation|regulation of chromosome inactivation|regulation of X chromosome inactivation						hjd	2012-02-14T07:29:45Z						biological_process											owl:Class	
GO:0019236	biolink:NamedThing	response to pheromone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.	got7fsn_ti	pheromone response													biological_process											owl:Class	
GO:0070782	biolink:NamedThing	phosphatidylserine exposure on apoptotic cell surface	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.	got7fsn_ti	externalization of phosphatidylserine				In normal cells, phosphatidylserine residues are found exclusively on the inner side of the cellular membrane. During apoptosis, phosphatidylserine is transported to the outer cell surface by scramblase proteins. This event acts as an "eat-me" signal for macrophages to dispose of the dying cell. When annotating to this term, curators should be aware of the following: 1) phosphatidylserine exposure on the cell surface can occur in circumstances other than apoptosis (for example, when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system, see PMID:21107324). Do not annotate to GO:0070782 unless phosphatidylserine exposure is shown to be part of an apoptotic event. 2) Caution should be applied when a study quotes annexin V assays. The annexin A5 protein binds to phosphatidylserine-containing membrane surfaces, which are usually only present on the inner leaflet of the membrane. However, in cells undergoing apoptosis, phosphatidylserine becomes exposed on the outer leaflet of the membrane. A positive annexin assay can therefore be linked to apoptotic death, but it shouldn't be confused with molecular events strictly involved in the process of phosphatidylserine exposure.		mah	2009-07-02T02:41:44Z						biological_process											owl:Class	
GO:0036302	biolink:NamedThing	atrioventricular canal development	The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.	got7fsn_ti							bf	2012-08-08T09:55:37Z						biological_process											owl:Class	
GO:0001702	biolink:NamedThing	gastrulation with mouth forming second	A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.	got7fsn_ti	deuterostomic gastrulation										GO:0010003|GO:0048276			biological_process											owl:Class	
NCBITaxon:33511	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0039019	biolink:NamedThing	pronephric nephron development	The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros.	got7fsn_ti							bf	2010-07-02T10:10:20Z						biological_process											owl:Class	
GO:0032119	biolink:NamedThing	sequestering of zinc ion	The process of binding or confining zinc ions such that they are separated from other components of a biological system.	got7fsn_ti														biological_process											owl:Class	
GO:1990963	biolink:NamedThing	establishment of blood-retinal barrier	Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type.	got7fsn_ti	establishment of blood-retina barrier|establishment of BRB						sl	2016-06-07T21:17:55Z						biological_process											owl:Class	
GO:0009840	biolink:NamedThing	chloroplastic endopeptidase Clp complex	A Clp endopeptidase complex located in the chloroplast.	got7fsn_ti														cellular_component											owl:Class	
GO:0060332	biolink:NamedThing	positive regulation of response to interferon-gamma	Any process that increases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.	got7fsn_ti	positive regulation of response to immune interferon|positive regulation of response to type II IFN|positive regulation of response to gamma-interferon|positive regulation of response to type II interferon													biological_process											owl:Class	
GO:0099003	biolink:NamedThing	vesicle-mediated transport in synapse	Any vesicle-mediated transport that occurs in a synapse.	got7fsn_ti														biological_process											owl:Class	
GO:0002784	biolink:NamedThing	regulation of antimicrobial peptide production	Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.	got7fsn_ti														biological_process											owl:Class	
GO:0019730	biolink:NamedThing	antimicrobial humoral response	An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.	got7fsn_ti											GO:0006960|GO:0019735			biological_process											owl:Class	
GO:0035633	biolink:NamedThing	maintenance of blood-brain barrier	Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation.	got7fsn_ti	maintenance of BBB|maintenance of blood/brain barrier				Homeostasis and maintenance processes are regulatory processes, therefore, regulation child terms, such as: regulation of maintenance of blood-brain barrier, should not exist for these terms.  Instead, for capturing regulation at the blood-brain barrier, consider using the part_of child term: regulation of blood-brain barrier permeability.		bf	2011-01-07T10:33:11Z						biological_process											owl:Class	
GO:1905499	biolink:NamedThing	trichome papilla formation	The aggregation, arrangement and bonding together of a set of components to form a trichome papilla.	got7fsn_ti	trichome papilla assembly						tb	2016-09-27T00:28:06Z						biological_process											owl:Class	
GO:0044735	biolink:NamedThing	envenomation resulting in negative regulation of acid-sensing ion channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.	got7fsn_ti	envenomation resulting in negative regulation of ASIC channel activity in other organism						jl	2012-11-06T16:05:58Z						biological_process											owl:Class	
GO:0044738	biolink:NamedThing	negative regulation of acid-sensing ion channel in other organism	Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism.	got7fsn_ti	negative regulation of ASIC channel in other organism						jl	2012-11-06T16:55:23Z						biological_process											owl:Class	
GO:0033163	biolink:NamedThing	microneme membrane	The lipid bilayer surrounding a microneme.	got7fsn_ti														cellular_component											owl:Class	
GO:0044327	biolink:NamedThing	dendritic spine head	Distal part of the dendritic spine, that carries the post-synaptic density.	got7fsn_ti	spine head						jl	2010-08-18T02:33:12Z				NIF_Subcellular:sao952643730		cellular_component											owl:Class	
GO:0014069	biolink:NamedThing	postsynaptic density	An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.	got7fsn_ti	neuronal postsynaptic density|post synaptic density|post-synaptic density|postsynaptic density of dendrite						pr	2013-07-02T09:44:28Z			GO:0097481|GO:0097483	Wikipedia:Postsynaptic_density|NIF_Subcellular:sao1196688972		cellular_component											owl:Class	
GO:0099565	biolink:NamedThing	chemical synaptic transmission, postsynaptic	The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.	got7fsn_ti	postsynaptic process involved in chemical synaptic transmission													biological_process											owl:Class	
GO:0006888	biolink:NamedThing	endoplasmic reticulum to Golgi vesicle-mediated transport	The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.	got7fsn_ti	anterograde vesicle-mediated transport, endoplasmic reticulum to Golgi|anterograde transport, endoplasmic reticulum to Golgi|rough ER to cis-Golgi transport|rough endoplasmic reticulum to cis-Golgi transport|rough ER to cis-Golgi vesicle-mediated transport|ER to Golgi vesicle-mediated transport|endoplasmic reticulum to Golgi vesicle-mediated transport|anterograde transport, ER to Golgi|rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|endoplasmic reticulum to Golgi transport|ER to Golgi transport|anterograde vesicle-mediated transport, ER to Golgi|anterograde (ER to Golgi) transport										GO:0048221			biological_process											owl:Class	
GO:0086061	biolink:NamedThing	voltage-gated sodium channel activity involved in bundle of His cell action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated sodium channel activity involved in bundle of His cardiac muscle cell action potential						dph	2011-11-17T12:58:13Z						molecular_function											owl:Class	
NCBITaxon:33392	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990770	biolink:NamedThing	small intestine smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.	got7fsn_ti							sl	2015-06-11T18:02:33Z						biological_process											owl:Class	
GO:0000084	biolink:NamedThing	mitotic S phase	The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.	got7fsn_ti	S phase of mitotic cell cycle|S-phase of mitotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0051329	biolink:NamedThing	mitotic interphase	The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.	got7fsn_ti	interphase of mitotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:1905293	biolink:NamedThing	negative regulation of neural crest cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation.	got7fsn_ti	down regulation of neural crest cell differentiation|down-regulation of neural crest cell differentiation|downregulation of neural crest cell differentiation|inhibition of neural crest cell differentiation						rl	2016-06-28T15:02:09Z						biological_process											owl:Class	
GO:1905224	biolink:NamedThing	clathrin-coated pit assembly	The aggregation, arrangement and bonding together of a set of components to form a clathrin-coated pit.	got7fsn_ti	coated pit assembly|coated pit formation|clathrin-coated pit formation						bf	2016-06-07T11:33:28Z						biological_process											owl:Class	
GO:0048268	biolink:NamedThing	clathrin coat assembly	The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.	got7fsn_ti	clathrin cage assembly													biological_process											owl:Class	
GO:0051283	biolink:NamedThing	negative regulation of sequestering of calcium ion	Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.	got7fsn_ti	negative regulation of calcium ion (Ca2+) sequestering|negative regulation of storage of calcium ion (Ca2+)|negative regulation of calcium ion (Ca2+) sequestration|inhibition of sequestering of calcium ion|negative regulation of sequestering of calcium ion (Ca2+)|negative regulation of calcium ion (Ca2+) storage|down regulation of sequestering of calcium ion|downregulation of sequestering of calcium ion|negative regulation of calcium ion (Ca2+) retention|negative regulation of retention of calcium ion (Ca2+)|negative regulation of sequestration of calcium ion (Ca2+)|down-regulation of sequestering of calcium ion													biological_process											owl:Class	
GO:0061399	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus.	got7fsn_ti							dph	2012-01-10T09:28:52Z						biological_process											owl:Class	
GO:0005944	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class IB	A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks.	got7fsn_ti	phosphoinositide 3-kinase complex, class IB|1-phosphatidylinositol-4-phosphate kinase, class IB complex|class IB PI3K complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex										GO:0035031			cellular_component											owl:Class	
GO:1904414	biolink:NamedThing	positive regulation of cardiac ventricle development	Any process that activates or increases the frequency, rate or extent of cardiac ventricle development.	got7fsn_ti	upregulation of cardiac ventricle development|up-regulation of cardiac ventricle development|activation of cardiac ventricle development|up regulation of cardiac ventricle development						sl	2015-06-25T19:52:27Z						biological_process											owl:Class	
GO:0046935	biolink:NamedThing	1-phosphatidylinositol-3-kinase regulator activity	Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity.	got7fsn_ti	1-phosphatidylinositol 3-kinase regulator activity|phosphatidylinositol 3-kinase, class I, regulator activity				See also the molecular function term '1-phosphatidylinositol-3-kinase activity ; GO:0016303'.									molecular_function											owl:Class	
GO:0016303	biolink:NamedThing	1-phosphatidylinositol-3-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).	got7fsn_ti	Vps34p|1-phosphatidylinositol 3-kinase activity|phosphatidylinositol 3-kinase activity, class III|type I phosphatidylinositol kinase activity|phosphatidylinositol 3-kinase activity, class I|phosphatidylinositol 3-kinase, class I, catalyst activity|PI3-kinase activity|type III phosphoinositide 3-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase activity|PI3K|phosphatidylinositol 3-kinase activity, class II|PtdIns-3-kinase activity										GO:0004429	Reactome:R-HSA-5672012|RHEA:12709|KEGG_REACTION:R03362|Reactome:R-HSA-6798174|MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN|EC:2.7.1.137|Reactome:R-HSA-1675961|Reactome:R-HSA-1676024|Reactome:R-HSA-109699|Reactome:R-HSA-1675939		molecular_function											owl:Class	
GO:0008919	biolink:NamedThing	lipopolysaccharide glucosyltransferase I activity	Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.	got7fsn_ti	UDP-glucose:lipopolysaccharide glucosyltransferase activity|lipopolysaccharide glucosyltransferase activity|UDPglucose:lipopolysaccharide glucosyltransferase activity|LPS glucosyltransferase I activity|uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I|UDPglucose:lipopolysaccharide glucosyltransferase I|uridine diphosphoglucose-lipopolysaccharide glucosyltransferase activity											EC:2.4.1.58|MetaCyc:2.4.1.58-RXN		molecular_function											owl:Class	
GO:0048493	biolink:NamedThing	plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex	A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.	got7fsn_ti	plasma membrane ribulose bisphosphate carboxylase complex|RubisCO complex|ribulose bisphosphate carboxylase complex													cellular_component											owl:Class	
GO:0050253	biolink:NamedThing	retinyl-palmitate esterase activity	Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+.	got7fsn_ti	retinyl palmitate hydrolyase activity|retinyl-palmitate palmitohydrolase activity|retinyl ester hydrolase activity|retinyl palmitate hydrolase activity											MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN|Reactome:R-HSA-975594|KEGG_REACTION:R02368|EC:3.1.1.21|RHEA:21508|Reactome:R-HSA-2404133|Reactome:R-HSA-8848355|Reactome:R-HSA-975593		molecular_function											owl:Class	
GO:1902175	biolink:NamedThing	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.	got7fsn_ti	regulation of intrinsic apoptotic signaling pathway in response to oxidative stress						pr	2013-05-29T18:30:00Z						biological_process											owl:Class	
GO:0036473	biolink:NamedThing	cell death in response to oxidative stress	Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus.	got7fsn_ti					This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred in response to an oxidative stress stimulus, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0097468 'programmed cell death in response to reactive oxygen species'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.		bf	2014-07-21T11:37:03Z						biological_process											owl:Class	
GO:0098645	biolink:NamedThing	collagen network	A supramolecular complex that consists of collagen triple helices associated to form a network.	got7fsn_ti														cellular_component											owl:Class	
GO:0000274	biolink:NamedThing	mitochondrial proton-transporting ATP synthase, stator stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core.	got7fsn_ti	mitochondrial proton-transporting ATP synthase, peripheral stalk													cellular_component											owl:Class	
GO:0000276	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0072200	biolink:NamedThing	negative regulation of mesenchymal cell proliferation involved in ureter development	Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	got7fsn_ti	negative regulation of ureteral mesenchymal cell proliferation|negative regulation of ureter mesenchymal cell proliferation						mah	2010-03-01T03:42:31Z						biological_process											owl:Class	
GO:0021646	biolink:NamedThing	vagus nerve formation	The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	got7fsn_ti	CN X formation|CN X biosynthesis													biological_process											owl:Class	
GO:0021644	biolink:NamedThing	vagus nerve morphogenesis	The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	got7fsn_ti	CN X morphogenesis													biological_process											owl:Class	
GO:0006489	biolink:NamedThing	dolichyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.	got7fsn_ti	dolichyl diphosphate formation|dolichyl diphosphate anabolism|dolichyl diphosphate synthesis|dolichyl diphosphate biosynthesis													biological_process											owl:Class	
GO:0030707	biolink:NamedThing	ovarian follicle cell development	The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0099054	biolink:NamedThing	presynapse assembly	The aggregation, arrangement and bonding together of a set of components to form a presynapse.	got7fsn_ti	presynapse biogenesis|presynaptic terminal assembly													biological_process											owl:Class	
GO:0015180	biolink:NamedThing	L-alanine transmembrane transporter activity	Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.	got7fsn_ti	L-alanine transporter activity													molecular_function											owl:Class	
GO:0015808	biolink:NamedThing	L-alanine transport	The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0072284	biolink:NamedThing	metanephric S-shaped body morphogenesis	The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.	got7fsn_ti							mah	2010-04-01T03:41:36Z						biological_process											owl:Class	
GO:1903378	biolink:NamedThing	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.	got7fsn_ti	activation of neuron apoptosis in response to oxidative stress|positive regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up regulation of neuron apoptosis in response to oxidative stress|up regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|upregulation of neuron apoptosis in response to oxidative stress|positive regulation of neuron apoptosis in response to oxidative stress|activation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of neuron apoptosis in response to oxidative stress|upregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress						bf	2014-08-26T13:03:36Z						biological_process											owl:Class	
GO:1900119	biolink:NamedThing	positive regulation of execution phase of apoptosis	Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.	got7fsn_ti	up-regulation of execution phase of apoptosis|up regulation of execution phase of apoptosis|upregulation of execution phase of apoptosis|activation of execution phase of apoptosis						pr	2012-02-22T11:26:27Z						biological_process											owl:Class	
GO:0044823	biolink:NamedThing	retroviral integrase activity	Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.	got7fsn_ti							jl	2014-02-04T14:09:34Z						molecular_function											owl:Class	
GO:0072223	biolink:NamedThing	metanephric glomerular mesangium development	The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.	got7fsn_ti							mah	2010-03-18T03:35:56Z						biological_process											owl:Class	
GO:0010465	biolink:NamedThing	nerve growth factor receptor activity	Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity.	got7fsn_ti	beta-nerve growth factor receptor activity|NGF receptor activity													molecular_function											owl:Class	
GO:0048406	biolink:NamedThing	nerve growth factor binding	Binding to nerve growth factor (NGF).	got7fsn_ti	neurotrophin TRKA receptor activity|beta-nerve growth factor binding|NGF binding													molecular_function											owl:Class	
GO:0045258	biolink:NamedThing	plasma membrane succinate dehydrogenase complex (ubiquinone)	The enzyme, located in the plasma membrane, that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration.	got7fsn_ti														cellular_component											owl:Class	
GO:0005840	biolink:NamedThing	ribosome	An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.	got7fsn_ti	free ribosome|ribosomal RNA|membrane bound ribosome										GO:0033279	NIF_Subcellular:sao1429207766|Wikipedia:Ribosome		cellular_component											owl:Class	
GO:0061071	biolink:NamedThing	urethra epithelium development	The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.	got7fsn_ti							dph	2010-03-12T08:36:53Z						biological_process											owl:Class	
GO:0051330	biolink:NamedThing	meiotic G1 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.	got7fsn_ti	G1 phase of meiotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0017015	biolink:NamedThing	regulation of transforming growth factor beta receptor signaling pathway	Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.	got7fsn_ti	regulation of TGF-beta receptor signaling pathway|regulation of TGFbeta receptor signaling pathway|regulation of transforming growth factor beta receptor signalling pathway													biological_process											owl:Class	
GO:0071560	biolink:NamedThing	cellular response to transforming growth factor beta stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.	got7fsn_ti	cellular response to TGFbeta stimulus|cellular response to TGF-beta stimulus						mah	2010-01-20T11:51:18Z						biological_process											owl:Class	
GO:0030314	biolink:NamedThing	junctional membrane complex	Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules).	got7fsn_ti	triad junction													cellular_component											owl:Class	
GO:2000062	biolink:NamedThing	negative regulation of ureter smooth muscle cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.	got7fsn_ti							jl	2010-08-20T01:44:23Z						biological_process											owl:Class	
GO:0038121	biolink:NamedThing	C-C motif chemokine 21 receptor activity	Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	CCL21 receptor activity						bf	2012-03-22T01:28:06Z						molecular_function											owl:Class	
GO:0038116	biolink:NamedThing	chemokine (C-C motif) ligand 21 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	chemokine (C-C motif) ligand 21 signalling pathway|C-C chemokine receptor type 7 signaling pathway|CCL21-mediated signaling pathway				The C-C chemokine CCL21 s a known agonist of the chemokine receptor type 7 (CCR7). Consider instead annotating to the child term 'CCL21-activated CCR7 signaling pathway ; GO:0038120'.		bf	2012-03-22T11:30:47Z						biological_process											owl:Class	
GO:0032338	biolink:NamedThing	regulation of inhibin secretion	Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0050886	biolink:NamedThing	endocrine process	The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.	got7fsn_ti	endocrine physiology|endocrine physiological process													biological_process											owl:Class	
GO:0015115	biolink:NamedThing	silicate transmembrane transporter activity	Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.	got7fsn_ti														molecular_function											owl:Class	
GO:0015708	biolink:NamedThing	silicic acid import across plasma membrane	The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.	got7fsn_ti	silicon uptake|silicic acid transport|silicic acid import|silicate transport						tb	2013-04-17T20:53:16Z			GO:1902067|GO:0051207			biological_process											owl:Class	
GO:0061053	biolink:NamedThing	somite development	The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.	got7fsn_ti							dph	2010-03-02T12:05:13Z						biological_process											owl:Class	
GO:0061009	biolink:NamedThing	common bile duct development	The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine.	got7fsn_ti	extrahepatic bile duct development|bile duct development|CBD development|EHBD development						dph	2010-01-22T09:17:13Z						biological_process											owl:Class	
GO:0061008	biolink:NamedThing	hepaticobiliary system development	The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.	got7fsn_ti	hepatobiliary system development						dph	2010-01-22T09:11:59Z						biological_process											owl:Class	
GO:0015112	biolink:NamedThing	nitrate transmembrane transporter activity	Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other.	got7fsn_ti	nitrite/nitrate porter activity	https://github.com/geneontology/go-ontology/issues/21337										RHEA:34923		molecular_function											owl:Class	
GO:0015706	biolink:NamedThing	nitrate transport	The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	low affinity nitrate transport|low-affinity nitrate transport										GO:0006872|GO:0080055			biological_process											owl:Class	
GO:1902423	biolink:NamedThing	regulation of attachment of mitotic spindle microtubules to kinetochore	Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.	got7fsn_ti	regulation of attachment of spindle microtubules to mitotic chromosome|regulation of attachment of spindle microtubules to kinetochore during mitosis|regulation of attachment of spindle microtubules to kinetochore involved in mitosis|regulation of mitotic bipolar attachment|regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|regulation of mitotic attachment of spindle microtubules to kinetochore						vw	2013-09-19T10:33:38Z						biological_process											owl:Class	
GO:0072021	biolink:NamedThing	ascending thin limb development	The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.	got7fsn_ti							mah	2010-01-25T02:37:13Z						biological_process											owl:Class	
GO:0072070	biolink:NamedThing	loop of Henle development	The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.	got7fsn_ti	intermediate tubule development						mah	2010-01-25T04:20:27Z			GO:0072018			biological_process											owl:Class	
GO:0048540	biolink:NamedThing	bursa of Fabricius development	The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.	got7fsn_ti														biological_process											owl:Class	
NCBITaxon:8457	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042714	biolink:NamedThing	dosage compensation complex assembly	The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes.	got7fsn_ti														biological_process											owl:Class	
GO:0075523	biolink:NamedThing	viral translational frameshifting	A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins.	got7fsn_ti	ribosomal frameshifting involved in viral translation				This term is intended to annotate gene products involved in the process of viral translational frameshifting, not viral proteins produced by this translation process.		jl	2011-08-03T02:48:46Z				VZ:860		biological_process											owl:Class	
GO:0006384	biolink:NamedThing	transcription initiation from RNA polymerase III promoter	Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.	got7fsn_ti	transcription initiation from RNA polymerase III type 2 promoter|transcription initiation from RNA polymerase III type 1 promoter|transcription initiation from RNA polymerase III type 3 promoter|transcription initiation from Pol III promoter|transcription initiation from RNA polymerase III hybrid type promoter				Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.		krc	2010-08-19T04:33:52Z			GO:0001022|GO:0001024|GO:0001036|GO:0001023			biological_process											owl:Class	
GO:0031588	biolink:NamedThing	nucleotide-activated protein kinase complex	A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).	got7fsn_ti	Snf1 kinase complex|AMP-activated protein kinase complex|SNF1/AMPK protein kinase complex|ADP-activated protein kinase complex|Snf1 serine/threonine protein kinase complex|AMPK complex|5'-AMP-activated protein kinase complex													cellular_component											owl:Class	
GO:0034743	biolink:NamedThing	APC-IQGAP complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.	got7fsn_ti					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0060322	biolink:NamedThing	head development	The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.	got7fsn_ti														biological_process											owl:Class	
GO:0030426	biolink:NamedThing	growth cone	The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.	got7fsn_ti												Wikipedia:Growth_cone		cellular_component											owl:Class	
GO:0071021	biolink:NamedThing	U2-type post-spliceosomal complex	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.	got7fsn_ti	yeast U2-type spliceosomal complex A2-3|mammalian U2-type spliceosomal complex C2|GT-AG post-spliceosomal complex|major post-spliceosomal complex						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0005078	biolink:NamedThing	MAP-kinase scaffold activity	The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.	got7fsn_ti	MAP-kinase scaffold protein activity													molecular_function											owl:Class	
GO:0043410	biolink:NamedThing	positive regulation of MAPK cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.	got7fsn_ti	upregulation of MAPKKK cascade|positive regulation of MAP kinase cascade|stimulation of MAPK cascade|positive regulation of MAPKKK cascade|up regulation of MAPKKK cascade|up-regulation of MAPK cascade|activation of MAPKKK cascade|positive regulation of mitogen-activated protein kinase cascade|positive regulation of mitogen-activated protein kinase kinase kinase cascade|up-regulation of MAPKKK cascade|activation of MAPK cascade|positive regulation of MAP kinase kinase kinase cascade|upregulation of MAPK cascade|stimulation of MAPKKK cascade|positive regulation of mitogen activated protein kinase kinase kinase cascade													biological_process											owl:Class	
GO:0048805	biolink:NamedThing	imaginal disc-derived genitalia morphogenesis	The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc.	got7fsn_ti	genital morphogenesis													biological_process											owl:Class	
GO:0042603	biolink:NamedThing	capsule	A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication.	got7fsn_ti											GO:0030113|GO:0042604	Wikipedia:Capsule_(microbiology)		cellular_component											owl:Class	
GO:0001520	biolink:NamedThing	outer dense fiber	A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins.	got7fsn_ti	outer dense fibre													cellular_component											owl:Class	
GO:0048567	biolink:NamedThing	ectodermal digestive tract morphogenesis	The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm.	got7fsn_ti	ectodermal gut morphogenesis													biological_process											owl:Class	
GO:1990719	biolink:NamedThing	C1 axonemal microtubule	One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections.	got7fsn_ti	C1 tubule						krc	2015-03-27T22:55:12Z						cellular_component											owl:Class	
GO:0097540	biolink:NamedThing	axonemal central pair	Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia.	got7fsn_ti	axoneme microtubule central pair|axonemal microtubule central pair|central-pair microtubules|central pair|axoneme central pair						pr	2013-12-12T11:07:09Z						cellular_component											owl:Class	
GO:0030905	biolink:NamedThing	retromer, tubulation complex	The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.	got7fsn_ti	SNX-BAR dimer|retromer complex, outer shell|heterodimeric membrane-deforming retromer subcomplex													cellular_component											owl:Class	
GO:0030904	biolink:NamedThing	retromer complex	A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.	got7fsn_ti														cellular_component											owl:Class	
GO:0036356	biolink:NamedThing	cyclic 2,3-diphosphoglycerate synthetase activity	Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate.	got7fsn_ti	CPGS activity|cDPGS activity				This reaction is the intramolecular cyclization of 2,3-diphosphoglycerate to cyclic 2,3-diphosphoglycerate and is the second step in the biosynthesis of cyclic 2,3-diphosphoglycerate (cDPG).		bf	2012-09-19T14:59:19Z						molecular_function											owl:Class	
GO:1901369	biolink:NamedThing	cyclic 2,3-bisphospho-D-glycerate biosynthetic process	The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid.	got7fsn_ti	cyclic 2,3-bisphospho-D-glyceric acid formation|cyclic 2,3-bisphospho-D-glyceric acid biosynthetic process|cyclic 2,3-diphosphoglycerate biosynthesis|cyclic 2,3-bisphospho-D-glyceric acid biosynthesis|cyclic 2,3-bisphospho-D-glyceric acid anabolism|cyclic 2,3-bisphospho-D-glyceric acid synthesis|cDPG biosynthesis						bf	2012-09-19T14:17:57Z						biological_process											owl:Class	
GO:0055008	biolink:NamedThing	cardiac muscle tissue morphogenesis	The process in which the anatomical structures of cardiac muscle tissue are generated and organized.	got7fsn_ti	myocardium morphogenesis|heart muscle morphogenesis													biological_process											owl:Class	
GO:0030935	biolink:NamedThing	sheet-forming collagen trimer	A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers assemble into a sheet.	got7fsn_ti	hexagonal network-forming collagen													cellular_component											owl:Class	
GO:0070450	biolink:NamedThing	interleukin4-interleukin-4 receptor complex	A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule.	got7fsn_ti	IL4-IL4 receptor complex|IL4-IL4R-IL2RG complex													cellular_component											owl:Class	
GO:1902675	biolink:NamedThing	left ventral basal body	Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage).	got7fsn_ti	ciliary basal body of left ventral flagellum|cilium basal body of left ventral cilium|left ventral flagellum ciliary basal body|microtubule basal body of left ventral cilium|cilial basal body of left ventral flagellum|ciliary basal body of left ventral cilium|microtubule basal body of left ventral flagellum|cilium basal body of left ventral flagellum|cilial basal body of left ventral cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:54:54Z						cellular_component											owl:Class	
GO:0034633	biolink:NamedThing	retinol transport	The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.	got7fsn_ti	vitamin A1 transport													biological_process											owl:Class	
GO:0016504	biolink:NamedThing	peptidase activator activity	Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.	got7fsn_ti	protease activator activity											Reactome:R-HSA-168865		molecular_function											owl:Class	
GO:0010952	biolink:NamedThing	positive regulation of peptidase activity	Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.	got7fsn_ti							tb	2009-04-27T11:54:32Z						biological_process											owl:Class	
GO:0035405	biolink:NamedThing	histone-threonine phosphorylation	The modification of histones by addition of a phosphate group to a threonine residue.	got7fsn_ti	histone threonine phosphorylation						bf	2010-03-24T10:09:21Z						biological_process											owl:Class	
GO:1905940	biolink:NamedThing	negative regulation of gonad development	Any process that stops, prevents or reduces the frequency, rate or extent of gonad development.	got7fsn_ti	negative regulation of gonadogenesis|downregulation of gonad development|downregulation of gonadogenesis|down regulation of gonadogenesis|inhibition of gonadogenesis|down regulation of gonad development|down-regulation of gonadogenesis|inhibition of gonad development|down-regulation of gonad development						hbye	2017-02-09T17:01:59Z						biological_process											owl:Class	
GO:0010060	biolink:NamedThing	negative regulation of atrichoblast fate specification	Any process that suppresses atrichoblast fate specification.	got7fsn_ti	downregulation of atrichoblast fate|down regulation of atrichoblast fate|inhibition of atrichoblast fate|down-regulation of atrichoblast fate													biological_process											owl:Class	
GO:0005915	biolink:NamedThing	zonula adherens	A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.	got7fsn_ti	adhesion belt|intermediate junction|belt desmosome|zonula adhaerens											NIF_Subcellular:sao1400623473		cellular_component											owl:Class	
GO:0043296	biolink:NamedThing	apical junction complex	A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.	got7fsn_ti	apical cell junction complex|apical junction													cellular_component											owl:Class	
GO:0061793	biolink:NamedThing	chromatin lock complex	A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping.	got7fsn_ti	nucleosome bridging complex						dph	2016-09-09T13:47:27Z						cellular_component											owl:Class	
GO:0061575	biolink:NamedThing	cyclin-dependent protein serine/threonine kinase activator activity	Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.	got7fsn_ti	cyclin-dependent protein kinase 5 activator activity						dph	2013-10-08T13:50:35Z			GO:0016535|GO:0016534			molecular_function											owl:Class	
GO:0045737	biolink:NamedThing	positive regulation of cyclin-dependent protein serine/threonine kinase activity	Any process that activates or increases the frequency, rate or extent of CDK activity.	got7fsn_ti	activation of cyclin-dependent protein kinase activity|upregulation of cyclin-dependent protein kinase activity|stimulation of cyclin-dependent protein kinase activity|up-regulation of cyclin-dependent protein kinase activity|positive regulation of CDK activity|up regulation of cyclin-dependent protein kinase activity|positive regulation of cyclin-dependent protein kinase activity													biological_process											owl:Class	
GO:0060468	biolink:NamedThing	prevention of polyspermy	The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.	got7fsn_ti	negative regulation of fertilization involved in egg activation|polyspermy block													biological_process											owl:Class	
GO:1990500	biolink:NamedThing	eif4e-cup complex	A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo.	got7fsn_ti	eukaryotic translation initiation factor 4E-cup complex				An example of this is Eif4e in drome (P48598) in PMID:14723848 (inferred from physical interaction).		bhm	2014-09-30T12:31:49Z						cellular_component											owl:Class	
GO:2000825	biolink:NamedThing	positive regulation of androgen receptor activity	Any process that activates or increases the frequency, rate or extent of androgen receptor activity.	got7fsn_ti							yaf	2011-07-15T10:56:14Z						biological_process											owl:Class	
GO:0002917	biolink:NamedThing	regulation of peripheral B cell anergy	Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.	got7fsn_ti														biological_process											owl:Class	
GO:0019724	biolink:NamedThing	B cell mediated immunity	Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.	got7fsn_ti	B-cell mediated immune effector process|B-lymphocyte mediated immune effector process|B lymphocyte mediated immunity|B lymphocyte mediated immune effector process|B-cell mediated immunity|B-lymphocyte mediated immunity													biological_process											owl:Class	
GO:0010323	biolink:NamedThing	negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).	got7fsn_ti	negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|inhibition of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|down regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|down-regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|downregulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway													biological_process											owl:Class	
GO:0008052	biolink:NamedThing	sensory organ boundary specification	The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained.	got7fsn_ti	sense organ boundary specification													biological_process											owl:Class	
GO:0097487	biolink:NamedThing	multivesicular body, internal vesicle	A membrane-bounded vesicle wholly contained within a multivesicular body.	got7fsn_ti							pr	2013-07-08T20:34:51Z						cellular_component											owl:Class	
GO:0016314	biolink:NamedThing	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.	got7fsn_ti	PI(3,4,5)P3 3-phosphatase activity|MMAC1|1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 3-phosphohydrolase activity|PtdIns(3,4,5)P3 3-phosphatase activity|PI(3)P 3-phosphatase activity|phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase activity											MetaCyc:3.1.3.67-RXN|RHEA:25017|Reactome:R-HSA-2317387|EC:3.1.3.67|Reactome:R-HSA-202237|Reactome:R-HSA-199456		molecular_function											owl:Class	
GO:0005931	biolink:NamedThing	axonemal nexin link	A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules.	got7fsn_ti	axonemal interdoublet link|nexin complex													cellular_component											owl:Class	
GO:0030671	biolink:NamedThing	clathrin-coated phagocytic vesicle membrane	The lipid bilayer surrounding a clathrin-coated phagocytic vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0048382	biolink:NamedThing	mesendoderm development	The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0048143	biolink:NamedThing	astrocyte activation	A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti														biological_process											owl:Class	
GO:1990901	biolink:NamedThing	old cell pole	The cell pole distal from the most recent cell division.	got7fsn_ti							pr	2015-11-17T16:42:16Z						cellular_component											owl:Class	
GO:0061235	biolink:NamedThing	mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti							dph	2010-08-19T02:57:11Z						biological_process											owl:Class	
GO:0010094	biolink:NamedThing	specification of carpel identity	The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0016010	biolink:NamedThing	dystrophin-associated glycoprotein complex	A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.	got7fsn_ti	DGC|dystrophin glycoprotein complex													cellular_component											owl:Class	
GO:1990225	biolink:NamedThing	rhoptry neck	Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion.	got7fsn_ti							pr	2013-11-03T14:19:26Z						cellular_component											owl:Class	
GO:0048864	biolink:NamedThing	stem cell development	The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0007597	biolink:NamedThing	blood coagulation, intrinsic pathway	A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.	got7fsn_ti					See also the biological process term 'blood coagulation, extrinsic pathway ; GO:0007598'.									biological_process											owl:Class	
GO:0032266	biolink:NamedThing	phosphatidylinositol-3-phosphate binding	Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.	got7fsn_ti	PtdIns-3-P binding|phosphatidylinositol 3-phosphate binding													molecular_function											owl:Class	
GO:0002331	biolink:NamedThing	pre-B cell allelic exclusion	Expression of a single heavy chain allele during pre-B cell differentiation.	got7fsn_ti	pre-B lymphocyte allelic exclusion													biological_process											owl:Class	
GO:0002329	biolink:NamedThing	pre-B cell differentiation	The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.	got7fsn_ti	pre-B cell development|pre-B lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:2000235	biolink:NamedThing	regulation of tRNA processing	Any process that modulates the frequency, rate or extent of tRNA processing.	got7fsn_ti	regulation of tRNA maturation						mah	2010-11-10T12:15:08Z						biological_process											owl:Class	
GO:1905699	biolink:NamedThing	regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	Any process that modulates the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	regulation of drug transmembrane export|regulation of xenobiotic transmembrane export	https://github.com/geneontology/go-ontology/issues/17083|https://github.com/geneontology/go-ontology/issues/19460					sl	2016-11-15T16:46:28Z						biological_process											owl:Class	
GO:0009410	biolink:NamedThing	response to xenobiotic stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	response to drug|drug resistance|drug susceptibility/resistance	https://github.com/geneontology/go-ontology/issues/19460									GO:0017035|GO:0042493|GO:0017104			biological_process											owl:Class	
GO:0051724	biolink:NamedThing	NAD transmembrane transporter activity	Enables the transfer of NAD from one side of a membrane to the other.	got7fsn_ti	oxidized nicotinamide adenine dinucleotide transmembrane transporter activity|NAD (oxidized) transporter activity|reduced NAD transporter activity|NAD (reduced) transporter activity|nicotinamide adenine dinucleotide transmembrane transporter activity|NAD transporter activity|reduced nicotinamide adenine dinucleotide transmembrane transporter activity|oxidized NAD transporter activity|NAD+ transporter activity|NADH transporter activity				NAD carrier		jl	2012-09-19T13:21:08Z			GO:1901368			molecular_function											owl:Class	
GO:0035352	biolink:NamedThing	NAD transmembrane transport	The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.	got7fsn_ti	NAD membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:46:20Z						biological_process											owl:Class	
GO:1901165	biolink:NamedThing	positive regulation of trophoblast cell migration	Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.	got7fsn_ti	activation of trophoblast cell migration|up regulation of trophoblast cell migration|up-regulation of trophoblast cell migration|upregulation of trophoblast cell migration						vk	2012-07-19T07:53:35Z						biological_process											owl:Class	
GO:0000932	biolink:NamedThing	P-body	A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.	got7fsn_ti	P body|cytoplasmic mRNA processing body|cytoplasmic foci											Wikipedia:P_body		cellular_component											owl:Class	
GO:0009099	biolink:NamedThing	valine biosynthetic process	The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.	got7fsn_ti	valine formation|valine synthesis|valine anabolism|valine biosynthesis											MetaCyc:VALSYN-PWY		biological_process											owl:Class	
GO:0099526	biolink:NamedThing	presynapse to nucleus signaling pathway	A series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).	got7fsn_ti	presynaptic signaling to nucleus				This class does not cover the cellular machinery (motor proteins, cargo-recognition proteins) that transports the signaling protein along the cytoskeleton towards the nucleus. For these cases, annotate to the appropriate transport/trafficking term.									biological_process											owl:Class	
GO:0048615	biolink:NamedThing	embryonic anterior midgut (ectodermal) morphogenesis	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0005863	biolink:NamedThing	striated muscle myosin thick filament	Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0005859	biolink:NamedThing	muscle myosin complex	A filament of myosin found in a muscle cell of any type.	got7fsn_ti														cellular_component											owl:Class	
GO:1990160	biolink:NamedThing	DnaB-DnaC-Rep-PriC complex	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.	got7fsn_ti	DnaB-DnaC-Rep-PriC preprimosome|phi-X174-type preprimosome						bhm	2013-08-02T12:05:25Z						cellular_component											owl:Class	
GO:0090734	biolink:NamedThing	site of DNA damage	A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.	got7fsn_ti							tb	2017-02-03T17:24:08Z				Wikipedia:DNA_repair		cellular_component											owl:Class	
GO:0032468	biolink:NamedThing	Golgi calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.	got7fsn_ti	regulation of calcium ion concentration in Golgi|regulation of Golgi calcium ion concentration|Golgi calcium ion concentration regulation|calcium ion homeostasis in Golgi													biological_process											owl:Class	
GO:0021767	biolink:NamedThing	mammillary body development	The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.	got7fsn_ti														biological_process											owl:Class	
GO:0003388	biolink:NamedThing	neuron development involved in amphid sensory organ development	The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.	got7fsn_ti							dph	2009-12-09T09:18:06Z						biological_process											owl:Class	
GO:0003387	biolink:NamedThing	neuron differentiation involved in amphid sensory organ development	The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland.	got7fsn_ti							dph	2009-12-09T09:15:00Z						biological_process											owl:Class	
GO:0097444	biolink:NamedThing	spine apparatus	A specialization of the endomembrane system found in some classes of dendritic spines consisting of two or more closely apposed lamellae with interspersed electron dense material.  The endomembrane component is continuous with the smooth endoplasmic reticulum.	got7fsn_ti	dense material						pr	2012-12-06T14:05:58Z				NIF_Subcellular:sao725931194		cellular_component											owl:Class	
GO:0032969	biolink:NamedThing	endosomal scaffold complex	A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling.	got7fsn_ti	MP1-p14 scaffolding complex|endosomal adaptor complex													cellular_component											owl:Class	
GO:0031902	biolink:NamedThing	late endosome membrane	The lipid bilayer surrounding a late endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0061134	biolink:NamedThing	peptidase regulator activity	Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.	got7fsn_ti							dph	2010-05-17T01:15:24Z						molecular_function											owl:Class	
GO:1905424	biolink:NamedThing	regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.	got7fsn_ti	regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wg signalling pathway involved in mDA neuron differentiation|regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|regulation of Wg signaling pathway involved in mDA neuron differentiation|regulation of Wg signalling pathway involved in midbrain DA neurogenesis|regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wingless signalling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wingless signaling pathway involved in mDA neuron differentiation|regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signaling pathway involved in mDA neuron differentiation|regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt-mediated midbrain DA neuron differentiation|regulation of Wnt signaling pathway involved in mDA neuron differentiation|regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of midbrain dopaminergic neuron differentiation by regulation of Wnt signaling|regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|regulation of Wg signaling pathway involved in midbrain DA neurogenesis|regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production						bf	2016-09-07T10:03:36Z						biological_process											owl:Class	
GO:1904948	biolink:NamedThing	midbrain dopaminergic neuron differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron.	got7fsn_ti	midbrain DA neurogenesis|mDA neuron differentiation|midbrain dopaminergic neuron production|DA neurogenesis from midbrain floor plate						bf	2016-02-04T14:38:10Z						biological_process											owl:Class	
GO:0071131	biolink:NamedThing	alphaV-beta3 integrin-laminin alpha-4 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4.	got7fsn_ti	ITGAV-ITGB3-LAMA4 complex						mah	2009-11-13T02:26:11Z						cellular_component											owl:Class	
GO:0086056	biolink:NamedThing	voltage-gated calcium channel activity involved in AV node cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated calcium channel activity involved in AV node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in atrioventricular node cardiac muscle cell action potential						dph	2011-11-17T12:24:22Z						molecular_function											owl:Class	
GO:0086045	biolink:NamedThing	membrane depolarization during AV node cell action potential	The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti	membrane depolarization during AV node cardiac muscle cell action potential|membrane depolarization during atrioventricular node cardiac muscle cell action potential						dph	2011-11-16T10:45:18Z						biological_process											owl:Class	
GO:0005682	biolink:NamedThing	U5 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U5, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U5 snRNP, most of which remain associated with the U5 snRNA both while the U5 snRNP is free or assembled into a series of spliceosomal complexes.	got7fsn_ti	snRNP U5													cellular_component											owl:Class	
GO:0006386	biolink:NamedThing	termination of RNA polymerase III transcription	The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues.	got7fsn_ti	transcription termination from RNA polymerase III promoter|RNA polymerase III transcription termination|RNA polymerase III transcription termination factor activity|transcription termination from Pol III promoter										GO:0019225			biological_process											owl:Class	
GO:0061283	biolink:NamedThing	specification of mesonephric distal tubule identity	The process in which the distal tubule of the mesonephric nephron acquires its identity.	got7fsn_ti							dph	2010-09-02T01:42:10Z						biological_process											owl:Class	
GO:0019910	biolink:NamedThing	mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex	A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus.	got7fsn_ti					See also the cellular component term 'mitochondrial pyruvate dehydrogenase complex ; GO:0005967'.									cellular_component											owl:Class	
GO:0035924	biolink:NamedThing	cellular response to vascular endothelial growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.	got7fsn_ti	cellular response to VEGFA|cellular response to vascular endothelial growth factor|cellular response to VEGFB|cellular response to VEGF						bf	2011-07-15T04:03:29Z						biological_process											owl:Class	
GO:0021781	biolink:NamedThing	glial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.	got7fsn_ti														biological_process											owl:Class	
GO:0036463	biolink:NamedThing	TRAIL receptor activity	Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death.	got7fsn_ti	tumor necrosis factor-related apoptosis-inducing ligand receptor						bf	2014-06-11T09:20:30Z						molecular_function											owl:Class	
GO:0045569	biolink:NamedThing	TRAIL binding	Binding to TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.	got7fsn_ti	Apo-2L binding													molecular_function											owl:Class	
GO:0071006	biolink:NamedThing	U2-type catalytic step 1 spliceosome	A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.	got7fsn_ti	major catalytic step 1 spliceosome|GT-AG catalytic step 1 spliceosome|mammalian U2-type spliceosomal complex B2|U2-type activated spliceosome|mammalian U2-type spliceosomal complex B*|yeast U2-type spliceosomal complex A1						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0021690	biolink:NamedThing	cerebellar molecular layer maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	got7fsn_ti														biological_process											owl:Class	
GO:0070517	biolink:NamedThing	DNA replication factor C core complex	A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37.	got7fsn_ti	RFC core complex													cellular_component											owl:Class	
GO:0061247	biolink:NamedThing	mesonephric glomerular mesangium development	The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.	got7fsn_ti							dph	2010-08-30T12:59:25Z						biological_process											owl:Class	
GO:0043363	biolink:NamedThing	nucleate erythrocyte differentiation	The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds.	got7fsn_ti	nucleate RBC differentiation|nucleate red blood cell differentiation													biological_process											owl:Class	
GO:0010216	biolink:NamedThing	maintenance of DNA methylation	Any process involved in maintaining the methylation state of a nucleotide sequence.	got7fsn_ti														biological_process											owl:Class	
GO:0071359	biolink:NamedThing	cellular response to dsRNA	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.	got7fsn_ti	cellular response to double-stranded RNA						mah	2009-12-11T03:00:32Z						biological_process											owl:Class	
GO:0070365	biolink:NamedThing	hepatocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.	got7fsn_ti	liver cell differentiation													biological_process											owl:Class	
GO:0070152	biolink:NamedThing	mitochondrial isoleucyl-tRNA aminoacylation	The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0000766	biolink:NamedThing	negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation	In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses.	got7fsn_ti	negative adaptation of signalling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation|desensitization to pheromone during pheromone-induced unidirectional conjugation|adaptation to pheromone during pheromone-induced unidirectional conjugation													biological_process											owl:Class	
GO:0000765	biolink:NamedThing	response to pheromone regulating pheromone-induced unidirectional conjugation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation.	got7fsn_ti	response to pheromone during pheromone-induced unidirectional													biological_process											owl:Class	
GO:0060709	biolink:NamedThing	glycogen cell differentiation involved in embryonic placenta development	The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.	got7fsn_ti							dph	2009-06-09T10:41:08Z						biological_process											owl:Class	
GO:0060712	biolink:NamedThing	spongiotrophoblast layer development	The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.	got7fsn_ti							dph	2009-06-09T03:33:40Z						biological_process											owl:Class	
GO:0060053	biolink:NamedThing	neurofilament cytoskeleton	Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons.	got7fsn_ti														cellular_component											owl:Class	
GO:0030295	biolink:NamedThing	protein kinase activator activity	Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0032147	biolink:NamedThing	activation of protein kinase activity	Any process that initiates the activity of an inactive protein kinase.	got7fsn_ti	protein kinase activation													biological_process											owl:Class	
GO:0032282	biolink:NamedThing	plastid acetyl-CoA carboxylase complex	An acetyl-CoA carboxylase complex located in the stroma of a plastid.	got7fsn_ti	plastid ACCase complex													cellular_component											owl:Class	
GO:0072115	biolink:NamedThing	head kidney morphogenesis	The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.	got7fsn_ti							mah	2010-02-22T11:13:37Z						biological_process											owl:Class	
GO:0048370	biolink:NamedThing	lateral mesoderm formation	The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	got7fsn_ti	lateral plate mesoderm formation|lateral plate mesoderm biosynthesis													biological_process											owl:Class	
GO:0070745	biolink:NamedThing	interleukin-35 complex	A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.	got7fsn_ti	EBI3|IL12A|p35|IL-35 complex				Note that this heterodimeric cytokine utilizes the same IL-12p35 subunit as its alpha chain as IL-12 uses and the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-27 uses. IL-35 requires both subunits -- there is no separate IL35 gene.		mah	2009-06-23T01:13:14Z						cellular_component											owl:Class	
GO:0048515	biolink:NamedThing	spermatid differentiation	The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti	spermatid cell differentiation													biological_process											owl:Class	
GO:0021735	biolink:NamedThing	dentate nucleus development	The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0060173	biolink:NamedThing	limb development	The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.	got7fsn_ti	limb bud development|paired limb/fin development											Wikipedia:Limb_development		biological_process											owl:Class	
NCBITaxon:33154	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009833	biolink:NamedThing	plant-type primary cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana.	got7fsn_ti	primary cell wall synthesis|primary cell wall formation|primary cell wall biogenesis|primary cell wall anabolism|cellulose and pectin-containing primary cell wall biogenesis|primary cell wall biosynthetic process													biological_process											owl:Class	
GO:0002102	biolink:NamedThing	podosome	An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.	got7fsn_ti					Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring components are found in focal adhesions and other cell-matrix contacts. Podosomes are typically found in cells that cross tissue boundaries, recruited to the leading edge of migrating cells, and are often sites of extracellular matrix degradation.							Wikipedia:Podosome		cellular_component											owl:Class	
GO:0004364	biolink:NamedThing	glutathione transferase activity	Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.	got7fsn_ti	glutathione S-alkyltransferase activity|glutathione S-aryltransferase activity|glutathione S-aralkyltransferase activity|glutathione S-alkyl transferase activity|RX:glutathione R-transferase activity|glutathione conjugation reaction|glutathione S-transferase activity|S-(hydroxyalkyl)glutathione lyase activity											Reactome:R-HSA-9026911|Reactome:R-HSA-9026780|Reactome:R-HSA-9026901|Reactome:R-HSA-5423653|Reactome:R-HSA-3301943|Reactome:R-HSA-9026777|MetaCyc:GSHTRAN-RXN|EC:2.5.1.18|Reactome:R-HSA-176059|Reactome:R-HSA-176054		molecular_function											owl:Class	
GO:0044284	biolink:NamedThing	mitochondrial crista junction	A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane.	got7fsn_ti	cristae junction|crista junction	https://github.com/geneontology/go-ontology/issues/18994					jl	2010-02-02T10:07:39Z						cellular_component											owl:Class	
GO:0042675	biolink:NamedThing	compound eye cone cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye.	got7fsn_ti											GO:0042674			biological_process											owl:Class	
GO:0005030	biolink:NamedThing	neurotrophin receptor activity	Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0072684	biolink:NamedThing	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic	Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion.	got7fsn_ti	mitochondrial endonucleolytic tRNA 3'-end cleavage|mitochondrial tRNA 3'-end cleavage, endonucleolytic|mitochondrial endonucleolytic tRNA 3'-trailer cleavage						mah	2011-02-23T01:32:52Z						biological_process											owl:Class	
GO:0061250	biolink:NamedThing	mesonephric glomerular epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.	got7fsn_ti							dph	2010-08-30T01:20:03Z						biological_process											owl:Class	
GO:0002910	biolink:NamedThing	positive regulation of peripheral B cell deletion	Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.	got7fsn_ti	up regulation of peripheral B cell deletion|upregulation of peripheral B cell deletion|activation of peripheral B cell deletion|up-regulation of peripheral B cell deletion|stimulation of peripheral B cell deletion													biological_process											owl:Class	
GO:0005933	biolink:NamedThing	cellular bud	A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.	got7fsn_ti														cellular_component											owl:Class	
GO:0072121	biolink:NamedThing	head kidney maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.	got7fsn_ti							mah	2010-02-22T11:28:08Z						biological_process											owl:Class	
GO:0019208	biolink:NamedThing	phosphatase regulator activity	Binds to and modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0060797	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate.	got7fsn_ti	transforming growth factor beta receptor signalling pathway involved in primary germ layer cell fate commitment						dph	2009-08-04T03:41:44Z						biological_process											owl:Class	
GO:0060795	biolink:NamedThing	cell fate commitment involved in formation of primary germ layer	The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.	got7fsn_ti							dph	2009-08-04T03:11:22Z						biological_process											owl:Class	
GO:0070938	biolink:NamedThing	contractile ring	A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.	got7fsn_ti	constriction ring|cytokinetic ring						mah	2009-09-22T02:41:32Z						cellular_component											owl:Class	
GO:0070144	biolink:NamedThing	mitochondrial arginyl-tRNA aminoacylation	The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0032865	biolink:NamedThing	ERMES complex	A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.	got7fsn_ti	ER-mitochondria encounter structure|mitochore|Mdm10/Mdm12/Mmm1 complex|MMM1 complex													cellular_component											owl:Class	
GO:0000466	biolink:NamedThing	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0045463	biolink:NamedThing	R8 cell development	The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium.	got7fsn_ti														biological_process											owl:Class	
GO:0045465	biolink:NamedThing	R8 cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor.	got7fsn_ti														biological_process											owl:Class	
GO:0072041	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.	got7fsn_ti	positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis						mah	2010-01-25T03:10:32Z						biological_process											owl:Class	
GO:0005342	biolink:NamedThing	organic acid transmembrane transporter activity	Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage.	got7fsn_ti														molecular_function											owl:Class	
GO:1903825	biolink:NamedThing	organic acid transmembrane transport	The process in which an organic acid is transported across a membrane.	got7fsn_ti							vw	2015-01-20T10:20:58Z						biological_process											owl:Class	
GO:0016325	biolink:NamedThing	oocyte microtubule cytoskeleton organization	Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte microtubule cytoskeleton organisation										GO:0048130			biological_process											owl:Class	
GO:0070676	biolink:NamedThing	intralumenal vesicle formation	The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.	got7fsn_ti	endosome membrane budding						mah	2009-05-29T02:02:30Z						biological_process											owl:Class	
GO:1904256	biolink:NamedThing	positive regulation of iron ion transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity.	got7fsn_ti	up regulation of iron cation channel activity|activation of iron channel activity|up-regulation of iron channel activity|up-regulation of iron-specific channel activity|positive regulation of iron transmembrane transporter activity|upregulation of iron cation channel activity|upregulation of iron channel activity|up-regulation of iron cation channel activity|up regulation of iron channel activity|up regulation of iron-specific channel activity|upregulation of iron-specific channel activity|activation of iron-specific channel activity|positive regulation of iron-specific channel activity|activation of iron cation channel activity|positive regulation of iron channel activity|positive regulation of iron cation channel activity						kom	2015-05-20T14:05:12Z						biological_process											owl:Class	
GO:0061804	biolink:NamedThing	mitotic spindle formation (spindle phase one)	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.	got7fsn_ti	mitotic spindle elongation during mitotic prophase|mitotic spindle elongation during prophase|mitotic spindle elongation during prophase and prometaphase						dph	2016-11-06T23:08:01Z						biological_process											owl:Class	
GO:0009863	biolink:NamedThing	salicylic acid mediated signaling pathway	A series of molecular signals mediated by salicylic acid.	got7fsn_ti	salicylic acid mediated signal transduction|salicylic acid mediated signalling pathway|salicylic acid-mediated signaling pathway													biological_process											owl:Class	
GO:0071446	biolink:NamedThing	cellular response to salicylic acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.	got7fsn_ti	cellular response to salicylate stimulus						mah	2009-12-16T04:14:16Z						biological_process											owl:Class	
GO:0004709	biolink:NamedThing	MAP kinase kinase kinase activity	Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.	got7fsn_ti	MEK kinase activity|MLK-like mitogen-activated protein triple kinase activity|MLTKb|MAPKKK activity|MEKK|MAP3K|cRaf|ATP:protein phosphotransferase (MAPKKKK-activated) activity|MEKK1|cMos|MAPK/ERK kinase kinase activity|REKS|mitogen-activated protein kinase kinase kinase activity|Mil/Raf|MEKK2|MEKK activity|MLTK|MLTKa|MEKK3|STK28										GO:0004710	Reactome:R-HSA-450346|Reactome:R-HSA-392530|Reactome:R-HSA-451649|Reactome:R-HSA-450337|EC:2.7.11.25|Reactome:R-HSA-933530|Reactome:R-HSA-2730887|Reactome:R-HSA-727819|Reactome:R-HSA-168184|MetaCyc:2.7.11.25-RXN		molecular_function											owl:Class	
GO:0000913	biolink:NamedThing	preprophase band assembly	The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation.	got7fsn_ti	preprophase band formation													biological_process											owl:Class	
GO:0002013	biolink:NamedThing	detection of carbon dioxide by vasomotor center	The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0015768	biolink:NamedThing	maltose transport	The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch.	got7fsn_ti														biological_process											owl:Class	
GO:0061234	biolink:NamedThing	mesonephric glomerulus morphogenesis	The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.	got7fsn_ti							dph	2010-08-19T02:53:35Z						biological_process											owl:Class	
GO:0015108	biolink:NamedThing	chloride transmembrane transporter activity	Enables the transfer of chloride ions from one side of a membrane to the other.	got7fsn_ti	ATPase-coupled chloride transmembrane transporter activity|chloride ABC transporter|ATP-dependent chloride transmembrane transporter activity|chloride-transporting ATPase activity|chloride transporting ATPase activity|chloride ion transmembrane transporter activity										GO:0008555	Reactome:R-HSA-5678992|MetaCyc:3.6.3.11-RXN|Reactome:R-HSA-5678863|Reactome:R-HSA-5678822|RHEA:29823		molecular_function											owl:Class	
GO:1902476	biolink:NamedThing	chloride transmembrane transport	The process in which chloride is transported across a membrane.	got7fsn_ti							bf	2013-10-28T09:44:29Z						biological_process											owl:Class	
GO:1903638	biolink:NamedThing	positive regulation of protein insertion into mitochondrial outer membrane	Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane.	got7fsn_ti	activation of protein transport into mitochondrial outer membrane|activation of mitochondrial outer membrane protein import|positive regulation of protein import into mitochondrial outer membrane|positive regulation of protein transport into mitochondrial outer membrane|activation of protein import into mitochondrial outer membrane|upregulation of mitochondrial outer membrane protein import|upregulation of protein insertion into mitochondrial outer membrane|up regulation of protein import into mitochondrial outer membrane|activation of protein insertion into mitochondrial outer membrane|up-regulation of protein insertion into mitochondrial outer membrane|up regulation of protein insertion into mitochondrial outer membrane|up-regulation of protein import into mitochondrial outer membrane|upregulation of protein import into mitochondrial outer membrane|upregulation of protein transport into mitochondrial outer membrane|up-regulation of mitochondrial outer membrane protein import|up-regulation of protein transport into mitochondrial outer membrane|up regulation of mitochondrial outer membrane protein import|positive regulation of mitochondrial outer membrane protein import|up regulation of protein transport into mitochondrial outer membrane						pga	2014-11-20T15:55:01Z						biological_process											owl:Class	
GO:1905209	biolink:NamedThing	positive regulation of cardiocyte differentiation	Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation.	got7fsn_ti	activation of cardiac cell differentiation|up regulation of cardiocyte differentiation|up-regulation of cardiocyte differentiation|positive regulation of heart cell differentiation|up-regulation of cardiac cell differentiation|upregulation of heart cell differentiation|up-regulation of heart cell differentiation|upregulation of cardiocyte differentiation|upregulation of cardiac cell differentiation|activation of heart cell differentiation|positive regulation of cardiac cell differentiation|activation of cardiocyte differentiation|up regulation of cardiac cell differentiation|up regulation of heart cell differentiation						bc	2016-06-02T07:20:16Z						biological_process											owl:Class	
GO:0019227	biolink:NamedThing	neuronal action potential propagation	The propagation of an action potential along an axon, away from the soma.	got7fsn_ti														biological_process											owl:Class	
GO:0072172	biolink:NamedThing	mesonephric tubule formation	The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.	got7fsn_ti							mah	2010-02-26T02:02:37Z						biological_process											owl:Class	
GO:0072171	biolink:NamedThing	mesonephric tubule morphogenesis	The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.	got7fsn_ti							mah	2010-02-26T02:02:13Z						biological_process											owl:Class	
GO:0150018	biolink:NamedThing	basal dendrite development	The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure.	got7fsn_ti							bc	2017-12-22T11:09:53Z						biological_process											owl:Class	
GO:0007453	biolink:NamedThing	clypeo-labral disc morphogenesis	The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus.	got7fsn_ti	clypeo-labral disc metamorphosis|morphogenesis of structures derived from the clypeo-labral disc													biological_process											owl:Class	
GO:0060601	biolink:NamedThing	lateral sprouting from an epithelium	The process in which a branch forms along the side of an epithelium.	got7fsn_ti							dph	2009-05-14T02:33:01Z						biological_process											owl:Class	
GO:0033550	biolink:NamedThing	MAP kinase tyrosine phosphatase activity	Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate.	got7fsn_ti	tyrosine-specific MAP kinase phosphatase activity													molecular_function											owl:Class	
GO:1990264	biolink:NamedThing	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity.	got7fsn_ti							al	2014-01-09T14:28:41Z						biological_process											owl:Class	
GO:0002811	biolink:NamedThing	negative regulation of antifungal peptide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis.	got7fsn_ti	down regulation of antifungal peptide biosynthetic process|downregulation of antifungal peptide biosynthetic process|down-regulation of antifungal peptide biosynthetic process|inhibition of antifungal peptide biosynthetic process													biological_process											owl:Class	
GO:0048811	biolink:NamedThing	male analia morphogenesis	The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc.	got7fsn_ti														biological_process											owl:Class	
GO:0005916	biolink:NamedThing	fascia adherens	A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighbouring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.	got7fsn_ti												Wikipedia:Fascia_adherens		cellular_component											owl:Class	
GO:0014704	biolink:NamedThing	intercalated disc	A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.	got7fsn_ti	intercalated disk											Wikipedia:Intercalated_disc		cellular_component											owl:Class	
GO:1904858	biolink:NamedThing	negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.	got7fsn_ti	inhibition of endothelial cell chemotaxis to vascular endothelial growth factor|down-regulation of endothelial cell chemotaxis to vascular endothelial growth factor|downregulation of endothelial cell chemotaxis to vascular endothelial growth factor|down regulation of endothelial cell chemotaxis to vascular endothelial growth factor						rph	2015-12-16T11:47:52Z						biological_process											owl:Class	
GO:1903089	biolink:NamedThing	5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity	Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other.	got7fsn_ti	acadesine transporter activity						mcc	2014-06-02T20:37:17Z						molecular_function											owl:Class	
GO:1903088	biolink:NamedThing	5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport	The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane.	got7fsn_ti							mcc	2014-06-02T20:34:58Z						biological_process											owl:Class	
GO:0071018	biolink:NamedThing	U12-type catalytic step 2 spliceosome	A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.	got7fsn_ti	minor catalytic step 2 spliceosome|mammalian U12-type spliceosomal complex C1|yeast U12-type spliceosomal complex A2-2|mammalian U12-type spliceosomal complex C|AT-AC catalytic step 2 spliceosome						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0021528	biolink:NamedThing	commissural neuron differentiation in spinal cord	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0140014	biolink:NamedThing	mitotic nuclear division	A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.	got7fsn_ti	mitosis	https://github.com/geneontology/go-ontology/issues/19910					pg	2017-03-23T14:44:23Z						biological_process											owl:Class	
GO:1990676	biolink:NamedThing	Golgi trans cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex.	got7fsn_ti	trans-Golgi cisterna membrane						bhm	2015-03-02T11:53:35Z						cellular_component											owl:Class	
GO:0097568	biolink:NamedThing	median body	A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc.	got7fsn_ti	parabasal body				Note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-11T13:34:19Z						cellular_component											owl:Class	
GO:0009657	biolink:NamedThing	plastid organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid.	got7fsn_ti	plastid organization and biogenesis|plastid organisation													biological_process											owl:Class	
GO:0009516	biolink:NamedThing	leucoplast	A colorless plastid involved in the synthesis of monoterpenes.	got7fsn_ti												Wikipedia:Leucoplast		cellular_component											owl:Class	
GO:0007585	biolink:NamedThing	respiratory gaseous exchange by respiratory system	The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.	got7fsn_ti	respiration|breathing													biological_process											owl:Class	
GO:0031595	biolink:NamedThing	nuclear proteasome complex	A proteasome found in the nucleus of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:1990499	biolink:NamedThing	raps-insc complex	Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).	got7fsn_ti	Rapsynoid-Inscuteable complex|partner of inscuteable-inscuteable complex				An example of this is Insc in drome (Q9W2R4) in PMID:22171003 (inferred from physical interaction).		bhm	2014-09-30T09:22:18Z						cellular_component											owl:Class	
GO:0060674	biolink:NamedThing	placenta blood vessel development	The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-06-02T01:09:43Z						biological_process											owl:Class	
GO:0008137	biolink:NamedThing	NADH dehydrogenase (ubiquinone) activity	Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).	got7fsn_ti	coenzyme Q reductase activity|NADH-CoQ oxidoreductase activity|NADH-ubiquinone oxidoreductase activity|DPNH-coenzyme Q reductase activity|NADH-ubiquinone reductase activity|mitochondrial electron transport complex 1 activity|dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity|NADH-coenzyme Q reductase activity|complex I (mitochondrial electron transport) activity|complex I (electron transport chain) activity|NADH-ubiquinone-1 reductase activity|ubiquinone reductase activity|DPNH-ubiquinone reductase activity|electron transfer complex I activity|reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity|NADH:ubiquinone oxidoreductase activity|mitochondrial electron transport complex I activity|NADH-Q6 oxidoreductase activity|type 1 dehydrogenase activity|NADH:ubiquinone oxidoreductase complex activity|complex I (NADH:Q1 oxidoreductase) activity|NADH coenzyme Q1 reductase activity|NADH-coenzyme Q oxidoreductase activity|complex 1 dehydrogenase activity|NADH-CoQ reductase activity	https://github.com/geneontology/go-ontology/issues/21275|https://github.com/geneontology/go-ontology/issues/20616										MetaCyc:NADH-DEHYDROG-A-RXN|MetaCyc:RXN0-5330|EC:7.1.1.2|Reactome:R-HSA-163217|RHEA:29091		molecular_function											owl:Class	
GO:0016079	biolink:NamedThing	synaptic vesicle exocytosis	Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.	got7fsn_ti														biological_process											owl:Class	
GO:1901992	biolink:NamedThing	positive regulation of mitotic cell cycle phase transition	Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition.	got7fsn_ti	up-regulation of mitotic cell cycle phase transition|upregulation of mitotic cell cycle phase transition|activation of mitotic cell cycle phase transition|up regulation of mitotic cell cycle phase transition						jl	2013-03-19T16:14:51Z						biological_process											owl:Class	
GO:0004136	biolink:NamedThing	deoxyadenosine kinase activity	Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+).	got7fsn_ti	deoxyadenosine kinase (phosphorylating)|purine-deoxyribonucleoside kinase activity|ATP:deoxyadenosine 5'-phosphotransferase activity											MetaCyc:DEOXYADENOSINE-KINASE-RXN|KEGG_REACTION:R02089|RHEA:23452|EC:2.7.1.76		molecular_function											owl:Class	
GO:0006170	biolink:NamedThing	dAMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).	got7fsn_ti	dAMP synthesis|dAMP anabolism|dAMP formation|dAMP biosynthesis													biological_process											owl:Class	
GO:0042438	biolink:NamedThing	melanin biosynthetic process	The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.	got7fsn_ti	melanin biosynthesis|melanin formation|melanin synthesis|melanin anabolism													biological_process											owl:Class	
GO:0031986	biolink:NamedThing	proteinoplast	A leucoplast in which protein is stored.	got7fsn_ti												Wikipedia:Proteinoplast		cellular_component											owl:Class	
GO:0048388	biolink:NamedThing	endosomal lumen acidification	Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion.	got7fsn_ti														biological_process											owl:Class	
GO:0007032	biolink:NamedThing	endosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.	got7fsn_ti	endosome organization and biogenesis|endosome organisation													biological_process											owl:Class	
GO:0007282	biolink:NamedThing	cystoblast division	Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells.	got7fsn_ti	cystoblast cell division													biological_process											owl:Class	
GO:0048891	biolink:NamedThing	lateral line ganglion neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.	got7fsn_ti	gLL neuron differentiation													biological_process											owl:Class	
GO:0021692	biolink:NamedThing	cerebellar Purkinje cell layer morphogenesis	The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	got7fsn_ti														biological_process											owl:Class	
GO:0021696	biolink:NamedThing	cerebellar cortex morphogenesis	The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	got7fsn_ti														biological_process											owl:Class	
GO:0033174	biolink:NamedThing	chloroplast proton-transporting ATP synthase complex, catalytic core CF(1)	The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits.	got7fsn_ti	chloroplast proton-transporting F-type ATPase complex, catalytic core CF(1)													cellular_component											owl:Class	
GO:2000595	biolink:NamedThing	regulation of optic nerve formation	Any process that modulates the frequency, rate or extent of optic nerve formation.	got7fsn_ti	regulation of CN II biosynthesis|regulation of CN II formation						yaf	2011-04-11T03:41:30Z						biological_process											owl:Class	
GO:0042151	biolink:NamedThing	nematocyst	An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus.	got7fsn_ti	cnidocyst											Wikipedia:Cnidocyte		cellular_component											owl:Class	
GO:0043188	biolink:NamedThing	cell septum edging	The cell wall material that surrounds the septum in fungal cells.	got7fsn_ti														cellular_component											owl:Class	
GO:0045120	biolink:NamedThing	pronucleus	The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.	got7fsn_ti												Wikipedia:Pronucleus		cellular_component											owl:Class	
GO:0003144	biolink:NamedThing	embryonic heart tube formation	The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.	got7fsn_ti							tb	2009-09-22T04:22:34Z						biological_process											owl:Class	
GO:1902375	biolink:NamedThing	nuclear tRNA 3'-trailer cleavage, endonucleolytic	Any tRNA 3'-trailer cleavage, endonucleolytic that takes place in nucleus.	got7fsn_ti	endonucleolytic tRNA 3'-trailer cleavage in cell nucleus|tRNA 3'-trailer cleavage, endonucleolytic in cell nucleus|tRNA 3'-end cleavage, endonucleolytic in cell nucleus|endonucleolytic tRNA 3'-end cleavage in nucleus|endonucleolytic tRNA 3'-end cleavage in cell nucleus|endonucleolytic tRNA 3'-trailer cleavage in nucleus|tRNA 3'-end cleavage, endonucleolytic in nucleus						al	2013-08-30T09:17:30Z						biological_process											owl:Class	
GO:0032231	biolink:NamedThing	regulation of actin filament bundle assembly	Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles.	got7fsn_ti	regulation of actin cable assembly|regulation of actin filament bundle formation													biological_process											owl:Class	
GO:0043600	biolink:NamedThing	cytoplasmic replisome	A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins.	got7fsn_ti	prokaryotic replisome													cellular_component											owl:Class	
GO:0043597	biolink:NamedThing	cytoplasmic replication fork	The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.	got7fsn_ti														cellular_component											owl:Class	
GO:0005897	biolink:NamedThing	interleukin-9 receptor complex	A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins.	got7fsn_ti	IL-9 receptor complex													cellular_component											owl:Class	
GO:0035050	biolink:NamedThing	embryonic heart tube development	The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.	got7fsn_ti														biological_process											owl:Class	
GO:0035876	biolink:NamedThing	maintenance of meiotic sister chromatid cohesion, arms	The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.	got7fsn_ti	maintenance of sister chromatin cohesion along arms at meiosis I|maintenance of meiotic sister chromatin cohesion along arms						bf	2011-05-31T09:37:53Z						biological_process											owl:Class	
GO:0051760	biolink:NamedThing	meiotic sister chromatid cohesion, arms	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis.	got7fsn_ti	sister chromatid cohesion along arms at meiosis I|meiotic sister chromatid cohesion along arms													biological_process											owl:Class	
GO:0150004	biolink:NamedThing	dendritic spine origin	The part of the dendritic spine neck where the spine arises from the dendritic shaft.	got7fsn_ti														cellular_component											owl:Class	
GO:0015694	biolink:NamedThing	mercury ion transport	The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	mercuric ion transport|mercury transport													biological_process											owl:Class	
GO:0050787	biolink:NamedThing	detoxification of mercury ion	Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]).	got7fsn_ti														biological_process											owl:Class	
GO:0039669	biolink:NamedThing	viral entry into host cell via pilus retraction and membrane fusion	The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane.	got7fsn_ti					For annotation of viral pilus-binding proteins, see also 'viral attachment to host cell pilus ; GO:0039666'.		bf	2013-09-04T14:35:44Z						biological_process											owl:Class	
GO:0019064	biolink:NamedThing	fusion of virus membrane with host plasma membrane	Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.	got7fsn_ti	viral envelope fusion with host cell membrane|viral-cell fusion molecule activity|viral penetration via membrane fusion|viral envelope fusion with host plasma membrane|viral entry into host cell via membrane fusion with the plasma membrane|viral envelope fusion|viral envelope fusion with host membrane										GO:0075706	VZ:987		biological_process											owl:Class	
GO:0043596	biolink:NamedThing	nuclear replication fork	The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.	got7fsn_ti														cellular_component											owl:Class	
GO:0071162	biolink:NamedThing	CMG complex	A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.	got7fsn_ti	unwindosome						mah	2009-11-19T11:04:13Z						cellular_component											owl:Class	
GO:1902668	biolink:NamedThing	negative regulation of axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance.	got7fsn_ti	downregulation of axon pathfinding|down-regulation of axon guidance|down regulation of axon growth cone guidance|down-regulation of axon chemotaxis|down-regulation of axon growth cone guidance|downregulation of axon chemotaxis|negative regulation of axon chemotaxis|down regulation of axon chemotaxis|negative regulation of axon growth cone guidance|downregulation of axon guidance|inhibition of axon pathfinding|downregulation of axon growth cone guidance|negative regulation of axon pathfinding|down-regulation of axon pathfinding|inhibition of axon growth cone guidance|inhibition of axon guidance|down regulation of axon guidance|inhibition of axon chemotaxis|down regulation of axon pathfinding						hjd	2014-01-31T18:50:19Z						biological_process											owl:Class	
GO:0097654	biolink:NamedThing	platelet SNARE complex	A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4.	got7fsn_ti							pr	2014-09-24T13:50:49Z						cellular_component											owl:Class	
GO:0098908	biolink:NamedThing	regulation of neuronal action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti	generation of action potential													biological_process											owl:Class	
GO:0005031	biolink:NamedThing	tumor necrosis factor-activated receptor activity	Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.	got7fsn_ti	tumor necrosis factor receptor activity, type I|NGF/TNF (6 C-domain) receptor activity|TNF receptor activity|TNF receptor activity, type II|tumor necrosis factor receptor activity, type II|TNF receptor activity, type I|tumor necrosis factor receptor activity										GO:0005032|GO:0005033			molecular_function											owl:Class	
GO:1990176	biolink:NamedThing	MalFGK2 complex	Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG.	got7fsn_ti	MalF-MalG-MalK-MalK complex|maltose transport MalFGK2 complex|MalF-MalG-MalK(2) complex|MalFGK(2) complex|maltose transport complex, core subunit				The MalFGK2 complex lacks the maltose-binding subunit present in GO:1990060.		bhm	2013-08-30T11:10:14Z						cellular_component											owl:Class	
GO:0014705	biolink:NamedThing	C zone	A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin.	got7fsn_ti														cellular_component											owl:Class	
GO:0043292	biolink:NamedThing	contractile fiber	Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.	got7fsn_ti	contractile fibre													cellular_component											owl:Class	
GO:0033080	biolink:NamedThing	immature T cell proliferation in thymus	The expansion of an immature T cell population by cell division in the thymus.	got7fsn_ti	thymocyte proliferation|thymocyte cell proliferation|thymic T cell proliferation													biological_process											owl:Class	
GO:0033077	biolink:NamedThing	T cell differentiation in thymus	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.	got7fsn_ti	T cell development in thymus|thymic T cell differentiation|thymocyte cell differentiation|thymocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0120003	biolink:NamedThing	hinge region between urothelial plaques of apical plasma membrane	A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12996					krc	2017-02-23T22:13:27Z						cellular_component											owl:Class	
GO:0016324	biolink:NamedThing	apical plasma membrane	The region of the plasma membrane located at the apical end of the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0048600	biolink:NamedThing	oocyte fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte.	got7fsn_ti														biological_process											owl:Class	
GO:0030970	biolink:NamedThing	retrograde protein transport, ER to cytosol	The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.	got7fsn_ti	retrograde protein transport, endoplasmic reticulum to cytosol|protein retrotranslocation, ER to cytosol|protein dislocation from ER													biological_process											owl:Class	
GO:0048840	biolink:NamedThing	otolith development	The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0016189	biolink:NamedThing	synaptic vesicle to endosome fusion	Fusion of a synaptic vesicle with an endosome.	got7fsn_ti					This covers fusion of synaptic vesicles trafficked to the synapse as well as fusion of endocytosed vesicles as part of recycling.  It is there for not  part of the synaptic vesicle cycle.									biological_process											owl:Class	
GO:0099532	biolink:NamedThing	synaptic vesicle endosomal processing	The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.	got7fsn_ti	synaptic vesicle processing via endosome				This covers processing of synaptic vesicles trafficked to synapse as well as  of endocytosed vesicles as part of recycling.  It is there for not part of the synaptic vesicle cycle.									biological_process											owl:Class	
GO:0030204	biolink:NamedThing	chondroitin sulfate metabolic process	The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate.	got7fsn_ti	chondroitin sulphate metabolic process|chondroitin sulfate metabolism|chondroitin sulphate metabolism													biological_process											owl:Class	
GO:0030222	biolink:NamedThing	eosinophil differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.	got7fsn_ti	eosinophil cell development|eosinophil development|eosinophil cell differentiation										GO:0035856			biological_process											owl:Class	
GO:1990669	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane	The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.	got7fsn_ti	ER-Golgi intermediate compartment derived vesicle fusion with ER membrane|endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with ER membrane						bhm	2015-03-02T11:21:43Z						biological_process											owl:Class	
GO:0006890	biolink:NamedThing	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.	got7fsn_ti	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum|retrograde vesicle-mediated transport, Golgi to ER|cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|cis-Golgi to rough endoplasmic reticulum transport|cis-Golgi to rough ER transport|cis-Golgi to rough ER vesicle-mediated transport|retrograde transport, Golgi to ER|retrograde transport, Golgi to endoplasmic reticulum|retrograde (Golgi to ER) transport										GO:0048220			biological_process											owl:Class	
GO:1990657	biolink:NamedThing	iNOS-S100A8/A9 complex	A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine.	got7fsn_ti					An example of this is NOS2 in human (UniProt symbol P35228) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T11:00:49Z						cellular_component											owl:Class	
GO:0009876	biolink:NamedThing	pollen adhesion	The process in which pollen deposited on the stigma adheres to cells of the stigma.	got7fsn_ti														biological_process											owl:Class	
GO:0002810	biolink:NamedThing	regulation of antifungal peptide biosynthetic process	Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0097618	biolink:NamedThing	dinoflagellate sulcal notch	A dinoflagellate sulcus that extends all the way to the posterior end of the cell (also known as antapex). The presence of a sulcal notch makes the dinoflagellate hypocone appear bilobed.	got7fsn_ti	dinoflagellate sulcus notch|sulcal notch				The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. Also, the ventral (front) side of a dinoflagellate cell is the one where the sulcus is located (as opposed to the dorsal (back) side). The term 'sulcal notch' appears mostly in older literature; more recently, indication of a bilobed hypocone is used to express the same.		pr	2014-06-27T16:28:49Z						cellular_component											owl:Class	
GO:0062159	biolink:NamedThing	contractile vacuole complex	A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory.	got7fsn_ti	CVC						dph	2019-09-26T14:20:14Z						cellular_component											owl:Class	
GO:0043054	biolink:NamedThing	dauer exit	Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development.	got7fsn_ti	exit from nematode dormancy													biological_process											owl:Class	
GO:0048625	biolink:NamedThing	myoblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0045445	biolink:NamedThing	myoblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.	got7fsn_ti	myoblast cell differentiation													biological_process											owl:Class	
GO:0061639	biolink:NamedThing	Cdv-dependent cytokinesis	A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells.	got7fsn_ti							dph	2014-08-21T14:55:04Z						biological_process											owl:Class	
NCBITaxon:2157	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048616	biolink:NamedThing	post-embryonic anterior midgut (ectodermal) morphogenesis	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0000457	biolink:NamedThing	endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0002109	biolink:NamedThing	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0048741	biolink:NamedThing	skeletal muscle fiber development	The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	got7fsn_ti	skeletal myofibre development|skeletal myofiber development|skeletal muscle fibre development													biological_process											owl:Class	
GO:0007519	biolink:NamedThing	skeletal muscle tissue development	The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.	got7fsn_ti	myogenesis										GO:0048637			biological_process											owl:Class	
GO:0099534	biolink:NamedThing	calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration	The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations.	got7fsn_ti	presynaptic calcium ion buffering|calcium ion binding involved in regulation of presynaptic cytosolic calcium levels|regulation of presynaptic cytosolic calcium ion concentration by calcium ion buffering													molecular_function											owl:Class	
GO:0099523	biolink:NamedThing	presynaptic cytosol	The region of the cytosol consisting of all cytosol that is part of the presynapse.	got7fsn_ti														cellular_component											owl:Class	
GO:0019933	biolink:NamedThing	cAMP-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.	got7fsn_ti	adenosine 3',5'-cyclophosphate-mediated signalling|cyclic AMP-mediated signaling|3',5' cAMP-mediated signaling|cAMP-mediated signal transduction|3',5'-cAMP-mediated signaling|cAMP-mediated signalling|adenosine 3',5'-cyclophosphate-mediated signaling|3',5' cAMP-mediated signalling|cAMP signaling|3',5'-cAMP-mediated signalling|cAMP signalling|cyclic AMP-mediated signalling													biological_process											owl:Class	
GO:0061298	biolink:NamedThing	retina vasculature development in camera-type eye	The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.	got7fsn_ti	retinal vasculature development						dph	2010-09-06T03:27:06Z						biological_process											owl:Class	
GO:0010824	biolink:NamedThing	regulation of centrosome duplication	Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	got7fsn_ti														biological_process											owl:Class	
GO:0043588	biolink:NamedThing	skin development	The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.	got7fsn_ti	animal skin development													biological_process											owl:Class	
GO:0061113	biolink:NamedThing	pancreas morphogenesis	Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.	got7fsn_ti							dph	2010-05-05T11:55:30Z						biological_process											owl:Class	
GO:0031016	biolink:NamedThing	pancreas development	The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.	got7fsn_ti												Wikipedia:Pancreas		biological_process											owl:Class	
GO:0000027	biolink:NamedThing	ribosomal large subunit assembly	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.	got7fsn_ti	60S ribosomal subunit assembly|50S ribosomal subunit assembly													biological_process											owl:Class	
GO:0042273	biolink:NamedThing	ribosomal large subunit biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.	got7fsn_ti	ribosomal large subunit biogenesis and assembly													biological_process											owl:Class	
GO:0048222	biolink:NamedThing	glycoprotein network	An extracellular matrix part that consists of cross-linked glycoproteins.	got7fsn_ti	extensin											Wikipedia:Extensin		cellular_component											owl:Class	
GO:1990565	biolink:NamedThing	HSP90-CDC37 chaperone complex	A protein kinase chaperone complex required for the proper folding, maturation and stabilization of target proteins (mostly signalling protein kinases, some steroid hormone receptors), usually during or immediately after completion of translation. The highly conserved, phosphorylated CDC37-Ser13 (vertebrates) or cdc37-Ser14 (yeast) is essential for complex assembly and target protein binding. CDC37-Ser13 (Ser14) is phosphorylated by Casein kinase II (CK2), which in turn is a target of CDC37 creating a positive feedback loop. Complex binding also prevents rapid ubiquitin-dependent proteosomal degradation of target proteins.	got7fsn_ti					An example of this is HSP90AB1 in human (UniProt symbol P08238) in PMID:21855797 (inferred from direct assay).		bhm	2014-11-26T14:22:51Z						cellular_component											owl:Class	
GO:0016591	biolink:NamedThing	RNA polymerase II, holoenzyme	A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.	got7fsn_ti	DNA-directed RNA polymerase II, holoenzyme													cellular_component											owl:Class	
GO:0061724	biolink:NamedThing	lipophagy	The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions.	got7fsn_ti							dph	2015-07-08T13:38:19Z						biological_process											owl:Class	
GO:1905691	biolink:NamedThing	lipid droplet disassembly	The disaggregation of a lipid particle into its constituent components.	got7fsn_ti	lipid body disassembly|lipid droplet reserve breakdown|lipid particle disassembly|adiposome disassembly						pr	2016-11-14T13:39:06Z						biological_process											owl:Class	
GO:0050786	biolink:NamedThing	RAGE receptor binding	Binding to a RAGE receptor, the receptor for advanced glycation end-products.	got7fsn_ti	advanced glycation end-product receptor binding													molecular_function											owl:Class	
GO:0048686	biolink:NamedThing	regulation of sprouting of injured axon	Any process that modulates the frequency, rate or extent of sprouting of an injured axon.	got7fsn_ti														biological_process											owl:Class	
GO:2000121	biolink:NamedThing	regulation of removal of superoxide radicals	Any process that modulates the frequency, rate or extent of removal of superoxide radicals.	got7fsn_ti	regulation of removal of oxygen free radicals|regulation of removal of O2-						dhl	2010-09-27T05:30:37Z						biological_process											owl:Class	
GO:0000302	biolink:NamedThing	response to reactive oxygen species	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	got7fsn_ti	response to ROI|response to AOS|response to reactive oxidative species|response to ROS|response to reactive oxygen intermediate|response to active oxygen species													biological_process											owl:Class	
GO:0048224	biolink:NamedThing	lignin network	An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens.	got7fsn_ti														cellular_component											owl:Class	
GO:0009531	biolink:NamedThing	secondary cell wall	A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin.	got7fsn_ti												Wikipedia:Secondary_cell_wall		cellular_component											owl:Class	
GO:0070151	biolink:NamedThing	mitochondrial histidyl-tRNA aminoacylation	The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:1905790	biolink:NamedThing	regulation of mechanosensory behavior	Any process that modulates the frequency, rate or extent of mechanosensory behavior.	got7fsn_ti	regulation of behavioral response to mechanical stimulus|regulation of mechanosensory behaviour|regulation of behavioural response to mechanical stimulus						hbye	2017-01-09T15:17:07Z						biological_process											owl:Class	
GO:0002916	biolink:NamedThing	positive regulation of central B cell anergy	Any process that activates or increases the frequency, rate, or extent of central B cell anergy.	got7fsn_ti	up-regulation of central B cell anergy|up regulation of central B cell anergy|activation of central B cell anergy|upregulation of central B cell anergy|stimulation of central B cell anergy													biological_process											owl:Class	
GO:0061551	biolink:NamedThing	trigeminal ganglion development	The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.	got7fsn_ti	trigeminal ganglia development						dph	2013-07-10T08:42:19Z						biological_process											owl:Class	
GO:0035400	biolink:NamedThing	histone tyrosine kinase activity	Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic  chromosomes.	got7fsn_ti	histone-tyrosine kinase activity						bf	2010-03-24T09:59:15Z						molecular_function											owl:Class	
GO:0035406	biolink:NamedThing	histone-tyrosine phosphorylation	The modification of histones by addition of a phosphate group to a tyrosine residue.	got7fsn_ti	histone tyrosine phosphorylation						bf	2010-03-24T10:10:16Z						biological_process											owl:Class	
GO:0048618	biolink:NamedThing	post-embryonic foregut morphogenesis	The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0021636	biolink:NamedThing	trigeminal nerve morphogenesis	The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	got7fsn_ti	CN V morphogenesis													biological_process											owl:Class	
GO:0140690	biolink:NamedThing	dihydropyrimidine dehydrogenase (NAD+) complex	A heteromultimeric complex capable of dihydropyrimidine dehydrogenase (NAD+); in E. coli, composed of PreA and PreT.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21891					pg	2021-08-04T05:52:44Z				MetaCyc:CPLX0-7788		cellular_component											owl:Class	
GO:0071331	biolink:NamedThing	cellular response to hexose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.	got7fsn_ti							mah	2009-12-10T05:37:00Z						biological_process											owl:Class	
GO:0045873	biolink:NamedThing	negative regulation of sevenless signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway.	got7fsn_ti	negative regulation of sev signaling pathway|down-regulation of sevenless signaling pathway|inhibition of sevenless signaling pathway|negative regulation of sevenless signalling pathway|down regulation of sevenless signaling pathway|downregulation of sevenless signaling pathway													biological_process											owl:Class	
GO:0033569	biolink:NamedThing	lactoferrin transmembrane transporter activity	Enables the transfer of lactoferrin from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0062000	biolink:NamedThing	positive regulation of cardiac endothelial to mesenchymal transition	Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition.	got7fsn_ti							dph	2018-02-16T16:31:06Z						biological_process											owl:Class	
GO:0120268	biolink:NamedThing	paraflagellar rod assembly	The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme.	got7fsn_ti	PFR assembly|paraflagellar rod formation|paraflagellar rod biogenesis	https://github.com/geneontology/go-ontology/issues/20053					krc	2020-09-30T17:46:14Z						biological_process											owl:Class	
NCBITaxon:33682	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005302	biolink:NamedThing	L-tyrosine transmembrane transporter activity	Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid.	got7fsn_ti	L-tyrosine permease activity|L-tyrosine transporter activity|valine/tyrosine/tryptophan permease activity										GO:0015508			molecular_function											owl:Class	
GO:0015828	biolink:NamedThing	tyrosine transport	The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-tyrosine transport													biological_process											owl:Class	
GO:0060541	biolink:NamedThing	respiratory system development	The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.	got7fsn_ti							dph	2009-04-10T08:55:42Z						biological_process											owl:Class	
GO:0000486	biolink:NamedThing	cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0120216	biolink:NamedThing	matrilin complex	A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer.	got7fsn_ti	matrilin-1 complex|matrilin-4 complex|matrilin family complex|matrilin-3 complex|matrilin-2 complex						krc	2019-07-09T22:05:11Z						cellular_component											owl:Class	
GO:0000914	biolink:NamedThing	phragmoplast assembly	The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles).	got7fsn_ti	phragmoplast formation													biological_process											owl:Class	
GO:0001073	biolink:NamedThing	transcription antitermination factor activity, DNA binding	Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein.	got7fsn_ti	DNA binding transcription antitermination factor activity						krc	2010-10-21T05:18:52Z						molecular_function											owl:Class	
GO:0048867	biolink:NamedThing	stem cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0048865	biolink:NamedThing	stem cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell.	got7fsn_ti														biological_process											owl:Class	
GO:0005290	biolink:NamedThing	L-histidine transmembrane transporter activity	Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	got7fsn_ti	histidine/arginine/lysine/ornithine porter activity|L-histidine transporter activity													molecular_function											owl:Class	
GO:0089709	biolink:NamedThing	L-histidine transmembrane transport	The directed movement of L-histidine across a membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0014044	biolink:NamedThing	Schwann cell development	The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.	got7fsn_ti														biological_process											owl:Class	
GO:0008320	biolink:NamedThing	protein transmembrane transporter activity	Enables the transfer of a protein from one side of a membrane to the other.	got7fsn_ti	protein channel activity										GO:0015463|GO:0015266	Reactome:R-HSA-5250616|Reactome:R-HSA-5210947|Reactome:R-HSA-5244506|Reactome:R-HSA-1299475|Reactome:R-HSA-5229111|Reactome:R-HSA-5244428|Reactome:R-HSA-5205661|Reactome:R-HSA-5250972|Reactome:R-HSA-3149434|Reactome:R-HSA-9698930|Reactome:R-HSA-1268022|Reactome:R-HSA-5210943|Reactome:R-HSA-5246514|Reactome:R-HSA-9698933|Reactome:R-HSA-5244404|Reactome:R-HSA-5228406|Reactome:R-HSA-184269|Reactome:R-HSA-5336420|Reactome:R-HSA-9636375|Reactome:R-HSA-5250884		molecular_function											owl:Class	
GO:0048507	biolink:NamedThing	meristem development	The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0014801	biolink:NamedThing	longitudinal sarcoplasmic reticulum	The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae.	got7fsn_ti														cellular_component											owl:Class	
GO:0016529	biolink:NamedThing	sarcoplasmic reticulum	A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.	got7fsn_ti					See also the cellular component terms 'sarcoplasm ; GO:0016528', 'nuclear envelope ; GO:0005635' and 'endoplasmic reticulum ; GO:0005783'.						GO:0008221	Wikipedia:Endoplasmic_reticulum#Sarcoplasmic_reticulum		cellular_component											owl:Class	
GO:0043541	biolink:NamedThing	UDP-N-acetylglucosamine transferase complex	A multienzyme, heterooligomeric complex involved in dolichyl-linked oligosaccharide synthesis. In yeast the complex is composed of Alg7p, which catalyzes the first step (GlcNAc1-PP-Dol from dolichol-phosphate and UDP-GlcNAc), and Alg13p plus Alg14p, the catalytic and anchoring subunits respectively, which together catalyze the second step (GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc) of dolichyl-linked oligosaccharide synthesis.	got7fsn_ti					See also the molecular function term 'N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity ; GO:0004577'.									cellular_component											owl:Class	
GO:0090201	biolink:NamedThing	negative regulation of release of cytochrome c from mitochondria	Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.	got7fsn_ti					The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and negatively regulate this process.		tb	2009-12-18T11:35:20Z						biological_process											owl:Class	
GO:1990765	biolink:NamedThing	colon smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum.	got7fsn_ti							sl	2015-06-10T18:29:21Z						biological_process											owl:Class	
GO:0008135	biolink:NamedThing	translation factor activity, RNA binding	Functions during translation by binding to RNA during polypeptide synthesis at the ribosome.	got7fsn_ti	translation factor activity, nucleic acid binding													molecular_function											owl:Class	
GO:0003336	biolink:NamedThing	corneocyte desquamation	The delamination process that results in the shedding of a corneocyte from the surface of the epidermis.	got7fsn_ti	epidermal desquamation						dph	2009-11-24T09:11:53Z						biological_process											owl:Class	
GO:0003335	biolink:NamedThing	corneocyte development	The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis.	got7fsn_ti							dph	2009-11-24T09:01:02Z						biological_process											owl:Class	
GO:0021613	biolink:NamedThing	facial nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	got7fsn_ti	CN VII maturation													biological_process											owl:Class	
GO:0021561	biolink:NamedThing	facial nerve development	The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	got7fsn_ti	cranial nerve 7 development|CN VII development|cranial nerve VII development													biological_process											owl:Class	
GO:0035462	biolink:NamedThing	determination of left/right asymmetry in diencephalon	The establishment of the diencephalon with respect to the left and right halves.	got7fsn_ti							bf	2010-04-19T11:50:11Z						biological_process											owl:Class	
GO:0031606	biolink:NamedThing	cytosolic proteasome core complex, alpha-subunit complex	The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0009841	biolink:NamedThing	mitochondrial endopeptidase Clp complex	A Clp endopeptidase complex located in the mitochondrion.	got7fsn_ti														cellular_component											owl:Class	
GO:0044308	biolink:NamedThing	axonal spine	A spine that originates from the axon, usually from the initial segment.	got7fsn_ti	axon spine						jl	2010-02-05T04:22:13Z				NIF_Subcellular:sao18239917		cellular_component											owl:Class	
GO:0048197	biolink:NamedThing	Golgi membrane coat protein complex assembly	The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat.	got7fsn_ti	Golgi membrane bud coat oligomerisation|dictyosome membrane bud coat oligomerisation|dictyosome membrane binding by cytosolic coat proteins													biological_process											owl:Class	
GO:0021580	biolink:NamedThing	medulla oblongata formation	The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	got7fsn_ti	medulla biosynthesis|medulla formation|myelencephalon formation|myelencephalon biosynthesis													biological_process											owl:Class	
GO:0001959	biolink:NamedThing	regulation of cytokine-mediated signaling pathway	Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.	got7fsn_ti	regulation of cytokine and chemokine mediated signaling pathway|regulation of cytokine mediated signalling pathway|regulation of cytokine mediated signaling pathway													biological_process											owl:Class	
CL:0000210	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004385	biolink:NamedThing	guanylate kinase activity	Catalysis of the reaction: ATP + GMP = ADP + GDP.	got7fsn_ti	guanosine monophosphate kinase activity|GMP kinase activity|ATP:GMP phosphotransferase activity|ATP:(d)GMP phosphotransferase activity|5'-GMP kinase activity|deoxyguanylate kinase activity|membrane-associated guanylate kinase											EC:2.7.4.8|Reactome:R-HSA-73788|MetaCyc:GUANYL-KIN-RXN|RHEA:20780|Reactome:R-HSA-110133		molecular_function											owl:Class	
GO:0046037	biolink:NamedThing	GMP metabolic process	The chemical reactions and pathways involving GMP, guanosine monophosphate.	got7fsn_ti	GMP metabolism													biological_process											owl:Class	
GO:0035807	biolink:NamedThing	positive regulation of blood coagulation in other organism	Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.	got7fsn_ti	positive regulation of blood clotting in other organism|positive regulation by organism of blood coagulation in other organism|positive regulation by organism of blood clotting in other organism						bf	2011-04-20T11:43:37Z						biological_process											owl:Class	
GO:0090489	biolink:NamedThing	L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)	Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O.	got7fsn_ti	tryptophan N-monooxygenase activity						tb	2012-10-16T16:22:19Z						molecular_function											owl:Class	
GO:0071404	biolink:NamedThing	cellular response to low-density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.	got7fsn_ti	response to low-density lipoprotein particle stimulus|response to low-density lipoprotein particle|response to low density lipoprotein particle						mah	2009-12-14T02:51:57Z			GO:0055098			biological_process											owl:Class	
GO:0043196	biolink:NamedThing	varicosity	Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.	got7fsn_ti														cellular_component											owl:Class	
GO:0015106	biolink:NamedThing	bicarbonate transmembrane transporter activity	Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.	got7fsn_ti												RHEA:28695|Reactome:R-HSA-2752067		molecular_function											owl:Class	
GO:0015701	biolink:NamedThing	bicarbonate transport	The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0098962	biolink:NamedThing	regulation of postsynaptic neurotransmitter receptor activity	Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.	got7fsn_ti														biological_process											owl:Class	
GO:0044645	biolink:NamedThing	modulation of complement activation in other organism	A process that modulates the frequency, rate or extent of complement activation in a different organism.	got7fsn_ti	regulation of complement activation in other organism						jl	2012-07-11T12:37:50Z						biological_process											owl:Class	
GO:0072213	biolink:NamedThing	metanephric capsule development	The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	got7fsn_ti							mah	2010-03-18T01:25:19Z						biological_process											owl:Class	
GO:0016080	biolink:NamedThing	synaptic vesicle targeting	The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.	got7fsn_ti														biological_process											owl:Class	
GO:0006880	biolink:NamedThing	intracellular sequestering of iron ion	The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system.	got7fsn_ti	intracellular iron ion storage|intracellular retention of iron ion|intracellular iron ion sequestration|intracellular iron ion sequestering|intracellular iron ion retention|intracellular storage of iron ion|intracellular sequestration of iron ion													biological_process											owl:Class	
GO:0097565	biolink:NamedThing	right middle basal body pair	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.	got7fsn_ti					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:14:05Z						cellular_component											owl:Class	
GO:1902674	biolink:NamedThing	right posteriolateral basal body	Any ciliary basal body that is part of a right posteriolateral flagellum found in Giardia species (trophozoite stage).	got7fsn_ti	microtubule basal body of right posterolateral cilium|cilium basal body of right posterolateral flagellum|cilial basal body of right posteriolateral flagellum|right posteriolateral flagellum ciliary basal body|ciliary basal body of right posterolateral flagellum|microtubule basal body of right posterolateral flagellum|cilium basal body of right posteriolateral flagellum|cilium basal body of right posteriolateral cilium|cilial basal body of right posterolateral flagellum|ciliary basal body of right posterolateral cilium|cilial basal body of right posteriolateral cilium|microtubule basal body of right posteriolateral cilium|microtubule basal body of right posteriolateral flagellum|ciliary basal body of right posteriolateral cilium|cilium basal body of right posterolateral cilium|cilial basal body of right posterolateral cilium|ciliary basal body of right posteriolateral flagellum				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:52:04Z						cellular_component											owl:Class	
GO:0140676	biolink:NamedThing	oscillatory cAMP signaling	Fluctuation in the extracellular cAMP levels due to the alternate activation of adenylate cyclase, which produces cAMP, and phosphodiesterase, which degrades it. Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate.	got7fsn_ti	cAMP relay	https://github.com/geneontology/go-ontology/issues/21369					pg	2021-06-29T14:14:39Z						biological_process											owl:Class	
GO:0098789	biolink:NamedThing	pre-mRNA cleavage required for polyadenylation	The targeted, endonucleolytic cleavage of a pre-mRNA,  required for polyadenylation of the 3' end.  This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.	got7fsn_ti	cleavage and polyadenylylation specificity factor activity|pre-mRNA cleavage factor activity													biological_process											owl:Class	
GO:0002644	biolink:NamedThing	negative regulation of tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction.	got7fsn_ti	down-regulation of tolerance induction|downregulation of tolerance induction|inhibition of tolerance induction|down regulation of tolerance induction													biological_process											owl:Class	
GO:1903317	biolink:NamedThing	regulation of protein maturation	Any process that modulates the frequency, rate or extent of protein maturation.	got7fsn_ti							vw	2014-08-18T12:59:07Z						biological_process											owl:Class	
GO:1901893	biolink:NamedThing	positive regulation of cell septum assembly	Any process that activates or increases the frequency, rate or extent of cell septum assembly.	got7fsn_ti	up-regulation of cell septum assembly|up regulation of cell septum assembly|upregulation of cell septum assembly|activation of cell septum assembly						tb	2013-02-06T20:14:50Z						biological_process											owl:Class	
GO:0004839	biolink:NamedThing	ubiquitin activating enzyme activity	Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.	got7fsn_ti	E1 ubiquitin-activating enzyme				The ubiquitin activating enzyme catalyzes a ligation reaction.							Reactome:R-HSA-8852134|Reactome:R-HSA-8852132|Reactome:R-HSA-8852133|Reactome:R-HSA-8865050|Reactome:R-HSA-8865090|EC:6.2.1.45|Reactome:R-HSA-8865098		molecular_function											owl:Class	
GO:1990700	biolink:NamedThing	nucleolar chromatin organization	Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin.	got7fsn_ti	nucleolar chromatin organisation|establishment or maintenance of nucleolar chromatin architecture						mah	2015-03-16T12:11:01Z						biological_process											owl:Class	
GO:0050771	biolink:NamedThing	negative regulation of axonogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.	got7fsn_ti	down regulation of axonogenesis|inhibition of axonogenesis|down-regulation of axonogenesis|downregulation of axonogenesis													biological_process											owl:Class	
GO:0020004	biolink:NamedThing	symbiont-containing vacuolar space	The space between a symbiont plasma membrane and the symbiont-containing vacuole membrane.	got7fsn_ti	symbiont-containing vacuole space|parasitophorous vacuolar space													cellular_component											owl:Class	
GO:0070030	biolink:NamedThing	alphav-beta1 integrin-osteopontin complex	A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.	got7fsn_ti	ITGAV-ITGB1-SPP1 complex													cellular_component											owl:Class	
GO:0003171	biolink:NamedThing	atrioventricular valve development	The progression of the atrioventricular valve over time, from its formation to the mature structure.	got7fsn_ti	AV valve development						dph	2009-10-08T11:14:21Z						biological_process											owl:Class	
GO:0031666	biolink:NamedThing	positive regulation of lipopolysaccharide-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.	got7fsn_ti	up regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of LPS-mediated signaling pathway|activation of lipopolysaccharide-mediated signaling pathway|stimulation of lipopolysaccharide-mediated signaling pathway|up-regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signalling pathway|upregulation of lipopolysaccharide-mediated signaling pathway													biological_process											owl:Class	
GO:0000384	biolink:NamedThing	first spliceosomal transesterification activity	Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.	got7fsn_ti	lariat formation, 5'-splice site cleavage													molecular_function											owl:Class	
GO:0022889	biolink:NamedThing	serine transmembrane transporter activity	Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0032329	biolink:NamedThing	serine transport	The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	serine import						tb	2012-10-01T11:10:51Z			GO:0090478			biological_process											owl:Class	
GO:0003380	biolink:NamedThing	establishment or maintenance of cytoskeleton polarity involved in gastrulation	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.	got7fsn_ti							dph	2009-12-09T07:10:57Z						biological_process											owl:Class	
GO:0003379	biolink:NamedThing	establishment of cell polarity involved in gastrulation cell migration	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.	got7fsn_ti							dph	2009-12-09T06:54:44Z						biological_process											owl:Class	
GO:0010421	biolink:NamedThing	hydrogen peroxide-mediated programmed cell death	Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.	got7fsn_ti	programmed cell death in response to hydrogen peroxide													biological_process											owl:Class	
GO:0035073	biolink:NamedThing	pupariation	The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.	got7fsn_ti	puparium biosynthesis|puparium formation													biological_process											owl:Class	
GO:0035210	biolink:NamedThing	prepupal development	The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation.	got7fsn_ti					See also the fly_anatomy.ontology term 'prepupa ; FBbt:00002952'.									biological_process											owl:Class	
GO:0006392	biolink:NamedThing	transcription elongation from mitochondrial promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.	got7fsn_ti	RNA elongation from mitochondrial promoter													biological_process											owl:Class	
GO:0046873	biolink:NamedThing	metal ion transmembrane transporter activity	Enables the transfer of metal ions from one side of a membrane to the other.	got7fsn_ti	heavy metal-exporting ATPase activity|high affinity metal ion uptake transporter activity|heavy metal ion porter activity|heavy metal ion:hydrogen symporter activity|heavy metal ion transporter activity|low affinity metal ion uptake transporter activity													molecular_function											owl:Class	
GO:0030001	biolink:NamedThing	metal ion transport	The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	divalent metal ion transport|heavy metal ion transport										GO:0070838			biological_process											owl:Class	
GO:0051663	biolink:NamedThing	oocyte nucleus localization involved in oocyte dorsal/ventral axis specification	The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte.	got7fsn_ti	oocyte axis determination, oocyte nucleus localization|oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|establishment and maintenance of oocyte nucleus localization during oocyte axis determination|oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|oocyte nucleus localization during oocyte axis determination|oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification|oocyte nucleus localization involved in oocyte dorsoventral axis specification										GO:0051662			biological_process											owl:Class	
GO:1901020	biolink:NamedThing	negative regulation of calcium ion transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.	got7fsn_ti	inhibition of calcium ion transmembrane transporter activity|down-regulation of calcium ion transmembrane transporter activity|downregulation of calcium ion transmembrane transporter activity|down regulation of calcium ion transmembrane transporter activity						rl	2012-06-15T07:54:32Z						biological_process											owl:Class	
GO:0070588	biolink:NamedThing	calcium ion transmembrane transport	A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	calcium ion membrane transport|transmembrane calcium transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-04-28T10:44:09Z						biological_process											owl:Class	
GO:0000348	biolink:NamedThing	mRNA branch site recognition	Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.	got7fsn_ti	spliceosomal B complex biosynthesis|spliceosomal B complex formation|U2-type nuclear mRNA branch site recognition|nuclear mRNA branch site recognition|spliceosomal A complex formation|U12-type nuclear mRNA branch site recognition|spliceosomal A complex biosynthesis				Note that this step represents the formation of the B complex (yeast) or the A complex (mammalian).						GO:0000370|GO:0000371			biological_process											owl:Class	
GO:0033615	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0046572	biolink:NamedThing	versicolorin B synthase activity	Catalysis of the reaction: versiconal = versicolorin B + H2O.	got7fsn_ti												EC:4.2.1.143|RHEA:33859|MetaCyc:RXN-9494		molecular_function											owl:Class	
GO:1902176	biolink:NamedThing	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.	got7fsn_ti	negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|downregulation of intrinsic apoptotic signaling pathway in response to oxidative stress|down-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|inhibition of intrinsic apoptotic signaling pathway in response to oxidative stress|down regulation of intrinsic apoptotic signaling pathway in response to oxidative stress						pr	2013-05-29T18:30:05Z						biological_process											owl:Class	
GO:0006273	biolink:NamedThing	lagging strand elongation	The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12633												biological_process											owl:Class	
GO:0043137	biolink:NamedThing	DNA replication, removal of RNA primer	Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.	got7fsn_ti	Okazaki initiator RNA removal													biological_process											owl:Class	
GO:0097712	biolink:NamedThing	vesicle targeting, trans-Golgi to periciliary membrane compartment	The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.	got7fsn_ti							pr	2016-08-05T16:16:28Z						biological_process											owl:Class	
GO:0072109	biolink:NamedThing	glomerular mesangium development	The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.	got7fsn_ti							mah	2010-02-22T10:35:24Z						biological_process											owl:Class	
GO:0001850	biolink:NamedThing	complement component C3a binding	Binding to a C3a product of the complement cascade.	got7fsn_ti														molecular_function											owl:Class	
CL:0000623	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015591	biolink:NamedThing	D-ribose transmembrane transporter activity	Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.	got7fsn_ti														molecular_function											owl:Class	
GO:0015752	biolink:NamedThing	D-ribose transmembrane transport	The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.	got7fsn_ti	D-ribose transport													biological_process											owl:Class	
GO:0060460	biolink:NamedThing	left lung morphogenesis	The process in which anatomical structures of the left lung are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0060459	biolink:NamedThing	left lung development	The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.	got7fsn_ti	left pulmonary development													biological_process											owl:Class	
GO:0098027	biolink:NamedThing	virus tail, sheath	The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm.	got7fsn_ti	bacteriophage tail sheath						bm	2012-07-19T14:23:27Z						cellular_component											owl:Class	
GO:1990107	biolink:NamedThing	thiazole synthase activity	Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O.	got7fsn_ti	1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity				H2S can provide the sulfur in vitro. Part of the pathway for thiamine biosynthesis.		pr	2013-05-28T12:36:04Z				RHEA:26297		molecular_function											owl:Class	
CL:0000235	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046834	biolink:NamedThing	lipid phosphorylation	The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.	got7fsn_ti														biological_process											owl:Class	
GO:0032921	biolink:NamedThing	sarcosine oxidase complex	A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0090042	biolink:NamedThing	tubulin deacetylation	The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti							tb	2009-08-03T11:50:47Z						biological_process											owl:Class	
GO:0060439	biolink:NamedThing	trachea morphogenesis	The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.	got7fsn_ti														biological_process											owl:Class	
GO:0016323	biolink:NamedThing	basolateral plasma membrane	The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.	got7fsn_ti														cellular_component											owl:Class	
GO:0070197	biolink:NamedThing	meiotic attachment of telomere to nuclear envelope	The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.	got7fsn_ti	attachment of telomeres to nuclear envelope|attachment of telomeric chromatin to nuclear envelope	https://github.com/geneontology/go-ontology/issues/22043												biological_process											owl:Class	
GO:0007140	biolink:NamedThing	male meiotic nuclear division	A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.	got7fsn_ti	male meiosis|male nuclear division													biological_process											owl:Class	
GO:0003689	biolink:NamedThing	DNA clamp loader activity	Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis.	got7fsn_ti	PCNA loading activity|DNA-protein loading ATPase activity|DNA clamp loading ATPase activity|PCNA loading complex activity|protein-DNA loading ATPase activity										GO:0033170	Reactome:R-HSA-174439|Reactome:R-HSA-176264		molecular_function											owl:Class	
GO:0061935	biolink:NamedThing	fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes.	got7fsn_ti							dph	2017-09-05T18:38:08Z						biological_process											owl:Class	
GO:0008526	biolink:NamedThing	phosphatidylinositol transfer activity	Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	intermembrane phosphotidylinositol transfer activity|phosphatidylinositol carrier activity|intermembrane phosphatidylinositol transfer activity|phosphatidylinositol transfer activity|phosphatidylinositol transporter activity						krc	2017-03-17T04:22:47Z			GO:0120018	Reactome:R-HSA-8874470|Reactome:R-HSA-8869241		molecular_function											owl:Class	
GO:0035091	biolink:NamedThing	phosphatidylinositol binding	Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.	got7fsn_ti	phosphoinositide binding													molecular_function											owl:Class	
GO:0071763	biolink:NamedThing	nuclear membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.	got7fsn_ti	nuclear membrane organization and biogenesis|nuclear membrane organisation						mah	2010-03-29T03:59:35Z						biological_process											owl:Class	
GO:0022036	biolink:NamedThing	rhombomere cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell.	got7fsn_ti														biological_process											owl:Class	
GO:0086063	biolink:NamedThing	voltage-gated sodium channel activity involved in SA node cell action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated sodium channel activity involved in sinoatrial node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in SA node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in SAN cardiac muscle cell action potential|voltage-gated sodium channel activity involved in sinus node cardiac muscle cell action potential						dph	2011-11-17T01:53:08Z						molecular_function											owl:Class	
GO:0086046	biolink:NamedThing	membrane depolarization during SA node cell action potential	The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti	membrane depolarization involved in regulation of sinoatrial node cardiac muscle cell action potential|membrane depolarization involved in regulation of sinus node cardiac muscle cell action potential|membrane depolarization involved in regulation of SA node cardiac muscle cell action potential|membrane depolarization involved in regulation of SAN cardiac muscle cell action potential						dph	2011-11-16T10:52:57Z						biological_process											owl:Class	
GO:0009782	biolink:NamedThing	photosystem I antenna complex	The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).	got7fsn_ti														cellular_component											owl:Class	
GO:0001535	biolink:NamedThing	radial spoke head	Protein complex forming part of eukaryotic flagellar apparatus.	got7fsn_ti	radial spokehead													cellular_component											owl:Class	
GO:0008637	biolink:NamedThing	apoptotic mitochondrial changes	The morphological and physiological alterations undergone by mitochondria during apoptosis.	got7fsn_ti					This term was created to reflect the fundamental role of the mitochondrial compartment in apoptosis. Most processes under this node occur during the signaling phase of apoptosis, but e.g. GO:0043653 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed under the signaling phase. For this reason, the parent term GO:0008637 'apoptotic mitochondrial changes' is not linked to the signaling or execution phase specifically, but its descendants are when current knowledge allows for it.									biological_process											owl:Class	
GO:0001768	biolink:NamedThing	establishment of T cell polarity	The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.	got7fsn_ti	T-cell polarization|establishment of T-lymphocyte polarity|T cell polarization|T lymphocyte polarization|establishment of T-cell polarity|establishment of T lymphocyte polarity													biological_process											owl:Class	
GO:0007343	biolink:NamedThing	egg activation	The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.	got7fsn_ti												Wikipedia:Egg_activation		biological_process											owl:Class	
GO:0005712	biolink:NamedThing	chiasma	A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over.	got7fsn_ti												Wikipedia:Chiasma_(genetics)		cellular_component											owl:Class	
GO:0030553	biolink:NamedThing	cGMP binding	Binding to cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).	got7fsn_ti	3',5'-cGMP binding|3',5' cGMP binding|cyclic GMP binding													molecular_function											owl:Class	
GO:0071988	biolink:NamedThing	protein localization to spindle pole body	A process in which a protein is transported to, or maintained at, the spindle pole body.	got7fsn_ti	protein localisation to spindle pole body						mah	2010-10-25T10:56:33Z						biological_process											owl:Class	
GO:0043219	biolink:NamedThing	lateral loop	Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode.	got7fsn_ti	paranodal loop|Schwann cell paranodal termination|oligodendrocyte paranodal termination											NIF_Subcellular:sao1067215520|NIF_Subcellular:sao1354781919		cellular_component											owl:Class	
GO:0070115	biolink:NamedThing	organellar chromatophore intermembrane space	The region between the inner and outer lipid bilayers that surround an organellar chromatophore.	got7fsn_ti	Paulinella-type chromatophore intermembrane space													cellular_component											owl:Class	
GO:0000819	biolink:NamedThing	sister chromatid segregation	The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.	got7fsn_ti														biological_process											owl:Class	
GO:0009575	biolink:NamedThing	chromoplast stroma	The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material.	got7fsn_ti														cellular_component											owl:Class	
NCBITaxon:Union_0000006	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060713	biolink:NamedThing	labyrinthine layer morphogenesis	The process in which the labyrinthine layer of the placenta is generated and organized.	got7fsn_ti							dph	2009-06-10T08:10:19Z						biological_process											owl:Class	
GO:0006931	biolink:NamedThing	substrate-dependent cell migration, cell attachment to substrate	The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions.	got7fsn_ti	substrate-bound cell migration, cell attachment to substrate													biological_process											owl:Class	
GO:0015548	biolink:NamedThing	organomercurial transmembrane transporter activity	Enables the transfer of organomercurial compounds from one side of a membrane to the other. Organomercurial substances are any organic compound containing a mercury atom.	got7fsn_ti	carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|organomercurial transporter activity													molecular_function											owl:Class	
GO:0015897	biolink:NamedThing	organomercurial transport	The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom.	got7fsn_ti														biological_process											owl:Class	
GO:0005021	biolink:NamedThing	vascular endothelial growth factor-activated receptor activity	Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	vascular endothelial growth factor E-activated receptor activity|VEGFR activity|VEGF-C-activated receptor activity|VEGF-E-activated receptor activity|VEGF-A-activated receptor activity|VEGF receptor activity|VEGF-B-activated receptor activity|VEGF-activated receptor activity|VEGF-D-activated receptor activity|vascular endothelial growth factor receptor activity				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.						GO:0036327|GO:0036329|GO:0036326|GO:0036330|GO:0036328			molecular_function											owl:Class	
GO:0045262	biolink:NamedThing	plasma membrane proton-transporting ATP synthase complex, catalytic core F(1)	The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species.	got7fsn_ti	proton-transporting ATP synthase complex, catalytic core F(1)|hydrogen-transporting ATP synthase, F1 sector				See also the cellular component term 'plasma membrane ; GO:0005886'.									cellular_component											owl:Class	
GO:0045260	biolink:NamedThing	plasma membrane proton-transporting ATP synthase complex	A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species.	got7fsn_ti	hydrogen-translocating F-type ATPase complex|proton-transporting ATP synthase complex|plasma membrane hydrogen-translocating F-type ATPase complex|hydrogen-transporting ATP synthase										GO:0045256			cellular_component											owl:Class	
GO:0061691	biolink:NamedThing	detoxification of hydrogen peroxide	Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.	got7fsn_ti							dph	2015-05-05T12:42:18Z						biological_process											owl:Class	
GO:0042542	biolink:NamedThing	response to hydrogen peroxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0034584	biolink:NamedThing	piRNA binding	Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	got7fsn_ti	Piwi-associated RNA binding													molecular_function											owl:Class	
GO:0002179	biolink:NamedThing	homodimeric serine palmitoyltransferase complex	A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine.	got7fsn_ti					This complex occurs primarily in bacteria.		hjd	2010-12-03T10:50:59Z						cellular_component											owl:Class	
GO:0034590	biolink:NamedThing	L-hydroxyproline transmembrane transporter activity	Enables the transfer of L-hydroxyproline from one side of a membrane to the other.	got7fsn_ti	4-hydroxyproline transmembrane transporter activity											Reactome:R-HSA-6784213		molecular_function											owl:Class	
GO:0034589	biolink:NamedThing	hydroxyproline transport	The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-hydroxyproline transport|4-hydroxyproline transport													biological_process											owl:Class	
GO:0071134	biolink:NamedThing	alpha9-beta1 integrin-thrombospondin-1 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1.	got7fsn_ti	ITGA9-ITGB1-THBS1 complex						mah	2009-11-13T02:29:07Z						cellular_component											owl:Class	
GO:0072088	biolink:NamedThing	nephron epithelium morphogenesis	The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.	got7fsn_ti							mah	2010-02-08T01:19:06Z						biological_process											owl:Class	
GO:1900454	biolink:NamedThing	positive regulation of long-term synaptic depression	Any process that activates or increases the frequency, rate or extent of long term synaptic depression.	got7fsn_ti	positive regulation of long term synaptic depression|upregulation of LTD|up regulation of long term depression|positive regulation of long term depression|positive regulation of LTD|activation of long term synaptic depression|upregulation of long term depression|up regulation of LTD|activation of LTD|activation of long term depression|upregulation of long term synaptic depression|up-regulation of long term synaptic depression|up-regulation of long term depression|up regulation of long term synaptic depression|up-regulation of LTD						rl	2012-04-27T03:55:23Z						biological_process											owl:Class	
GO:0043996	biolink:NamedThing	histone acetyltransferase activity (H4-K8 specific)	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8).	got7fsn_ti	histone lysine N-acetyltransferase activity (H4-K8 specific)													molecular_function											owl:Class	
GO:0052807	biolink:NamedThing	aflatoxin reductase (coenzyme F420) activity	Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.	got7fsn_ti	aflatoxin:coenzyme F420 oxidoreductase activity|coenzyme F420-dependent aflatoxin reductase activity|aflatoxin:reduced coenzyme F420 reductase activity|coenzyme F420-aflatoxin reductase activity						ai	2011-09-22T04:08:13Z						molecular_function											owl:Class	
GO:0046223	biolink:NamedThing	aflatoxin catabolic process	The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.	got7fsn_ti	aflatoxin breakdown|aflatoxin catabolism|aflatoxin degradation													biological_process											owl:Class	
GO:0007056	biolink:NamedThing	spindle assembly involved in female meiosis	The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.	got7fsn_ti	female meiotic spindle assembly													biological_process											owl:Class	
GO:0042060	biolink:NamedThing	wound healing	The series of events that restore integrity to a damaged tissue, following an injury.	got7fsn_ti												Wikipedia:Wound_healing		biological_process											owl:Class	
GO:0048898	biolink:NamedThing	anterior lateral line system development	The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.	got7fsn_ti	ALL system development													biological_process											owl:Class	
GO:0032276	biolink:NamedThing	regulation of gonadotropin secretion	Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.	got7fsn_ti	regulation of gonadotrophin secretion													biological_process											owl:Class	
GO:0000222	biolink:NamedThing	plasma membrane proton-transporting V-type ATPase, V0 domain	The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.	got7fsn_ti	plasma membrane hydrogen ion-transporting ATPase V0 domain													cellular_component											owl:Class	
CHEBI:59789	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0021582	biolink:NamedThing	medulla oblongata maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	got7fsn_ti	myelencephalon maturation|medulla maturation													biological_process											owl:Class	
GO:1904600	biolink:NamedThing	actin fusion focus assembly	The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus.	got7fsn_ti	actin fusion focus formation	https://github.com/geneontology/go-ontology/issues/21688					al	2015-08-26T10:34:48Z						biological_process											owl:Class	
GO:0000747	biolink:NamedThing	conjugation with cellular fusion	A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	cell fusion|mating										GO:0007333|GO:0007322|GO:0030461|GO:0030477			biological_process											owl:Class	
GO:0020039	biolink:NamedThing	pellicle	The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.	got7fsn_ti														cellular_component											owl:Class	
GO:0021966	biolink:NamedThing	corticospinal neuron axon guidance	The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues.	got7fsn_ti	corticospinal neuron axon pathfinding													biological_process											owl:Class	
GO:0007605	biolink:NamedThing	sensory perception of sound	The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.	got7fsn_ti	perception of sound|hearing											Wikipedia:Hearing_(sense)		biological_process											owl:Class	
GO:0062009	biolink:NamedThing	secondary palate development	The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.	got7fsn_ti							dph	2018-02-26T22:55:20Z						biological_process											owl:Class	
GO:0009704	biolink:NamedThing	de-etiolation	The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll.	got7fsn_ti														biological_process											owl:Class	
GO:0052707	biolink:NamedThing	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine	The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).	got7fsn_ti	histidine catabolism to N-alpha,N-alpha,N-alpha-trimethyl-L-histidine|histidine betaine biosynthesis from histidine|hercynine biosynthesis from histidine|histidine catabolism to hercynine|histidine catabolic process to hercynine						ai	2011-08-05T02:07:24Z				KEGG_REACTION:R01169		biological_process											owl:Class	
GO:0052705	biolink:NamedThing	methylhistidine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine.	got7fsn_ti	S-adenosyl-L-methionine:alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity|histidine-alpha-N-methyltransferase activity|S-adenosyl-L-methionine:N-alpha-dimethyl-L-histidine N-alpha-methyltransferase activity|methylhistidine methyltransferase activity						ai	2011-08-05T11:54:54Z						molecular_function											owl:Class	
GO:0150069	biolink:NamedThing	negative regulation of tubulin deacetylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity.	got7fsn_ti							bc	2018-07-24T10:40:19Z						biological_process											owl:Class	
GO:0005747	biolink:NamedThing	mitochondrial respiratory chain complex I	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.	got7fsn_ti											GO:0005748			cellular_component											owl:Class	
GO:0030526	biolink:NamedThing	granulocyte macrophage colony-stimulating factor receptor complex	The heterodimeric receptor for granulocyte macrophage colony-stimulating factor.	got7fsn_ti	GM-CSF receptor complex|granulocyte macrophage colony stimulating factor receptor complex													cellular_component											owl:Class	
GO:0043404	biolink:NamedThing	corticotropin-releasing hormone receptor activity	Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity.	got7fsn_ti	corticotropin-releasing factor receptor activity|CRH receptor activity|adrenocorticotropin-releasing hormone receptor activity|CRF receptor activity										GO:0031636			molecular_function											owl:Class	
GO:0051424	biolink:NamedThing	corticotropin-releasing hormone binding	Binding to corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.	got7fsn_ti	corticotropin-releasing factor binding|CRF binding|corticoliberin binding|CRH binding										GO:0017047			molecular_function											owl:Class	
GO:0045494	biolink:NamedThing	photoreceptor cell maintenance	Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.	got7fsn_ti														biological_process											owl:Class	
GO:0042876	biolink:NamedThing	aldarate transmembrane transporter activity	Enables the transfer of aldarate from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042869	biolink:NamedThing	aldarate transmembrane transport	The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	aldarate transport													biological_process											owl:Class	
GO:0098643	biolink:NamedThing	banded collagen fibril	A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands).	got7fsn_ti														cellular_component											owl:Class	
PATO:0002309	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010095	biolink:NamedThing	specification of petal identity	The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0007129	biolink:NamedThing	homologous chromosome pairing at meiosis	The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.	got7fsn_ti	homologous chromosome pairing at meiosis|chromosomal synapsis|synapsis|chromosomal pairing											Wikipedia:Synapsis		biological_process											owl:Class	
GO:0048337	biolink:NamedThing	positive regulation of mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification.	got7fsn_ti	up regulation of mesodermal cell fate specification|upregulation of mesodermal cell fate specification|stimulation of mesodermal cell fate specification|activation of mesodermal cell fate specification|up-regulation of mesodermal cell fate specification													biological_process											owl:Class	
GO:0047270	biolink:NamedThing	lipopolysaccharide glucosyltransferase II activity	Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP.	got7fsn_ti	UDP-glucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity|UDPglucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity|LPS glucosyltransferase II activity|uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase activity											EC:2.4.1.73|MetaCyc:2.4.1.73-RXN		molecular_function											owl:Class	
GO:0032587	biolink:NamedThing	ruffle membrane	The portion of the plasma membrane surrounding a ruffle.	got7fsn_ti	membrane ruffle													cellular_component											owl:Class	
GO:0001726	biolink:NamedThing	ruffle	Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.	got7fsn_ti	membrane ruffle													cellular_component											owl:Class	
GO:0005971	biolink:NamedThing	ribonucleoside-diphosphate reductase complex	An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.	got7fsn_ti	RNR complex|ribonucleotide reductase complex													cellular_component											owl:Class	
GO:0140399	biolink:NamedThing	aflatoxin B synthase activity	Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O(2) <=> aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H(2)O + methanol + CO(2). Produces both aflatoxin B(1) and aflatoxin B(2).	got7fsn_ti							pg	2019-11-29T11:06:07Z				RHEA:35759|EC:1.14.14.117|MetaCyc:RXN-9497|MetaCyc:RXN-9502		molecular_function											owl:Class	
GO:0007598	biolink:NamedThing	blood coagulation, extrinsic pathway	A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X.	got7fsn_ti					See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.									biological_process											owl:Class	
GO:0072378	biolink:NamedThing	blood coagulation, fibrin clot formation	A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.	got7fsn_ti					See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.		mah	2010-11-22T03:09:32Z						biological_process											owl:Class	
GO:0016230	biolink:NamedThing	sphingomyelin phosphodiesterase activator activity	Increases the activity of the enzyme sphingomyelin phosphodiesterase.	got7fsn_ti	neutral sphingomyelinase activator													molecular_function											owl:Class	
GO:0072579	biolink:NamedThing	glycine receptor clustering	The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane.	got7fsn_ti							mah	2011-02-03T01:47:40Z						biological_process											owl:Class	
GO:0044480	biolink:NamedThing	envenomation resulting in positive regulation of mast cell degranulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:54:37Z						biological_process											owl:Class	
GO:0071697	biolink:NamedThing	ectodermal placode morphogenesis	The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.	got7fsn_ti							mah	2010-03-02T11:49:51Z						biological_process											owl:Class	
GO:0071587	biolink:NamedThing	CAAX-box protein modification	The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins.	got7fsn_ti							mah	2010-01-28T04:48:56Z						biological_process											owl:Class	
GO:0080120	biolink:NamedThing	CAAX-box protein maturation	A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase.	got7fsn_ti	CAAX-box protein processing|farnesylated protein maturation						dhl	2009-04-28T03:06:13Z						biological_process											owl:Class	
GO:0021943	biolink:NamedThing	formation of radial glial scaffolds	The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells.	got7fsn_ti	Bergmann fiber biosynthesis|Bergmann fiber formation													biological_process											owl:Class	
CL:0000681	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033374	biolink:NamedThing	protein localization to T cell secretory granule	A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.	got7fsn_ti	protein localization in T lymphocyte secretory granule|protein localisation in T cell secretory granule|protein localization in T-cell secretory granule|protein localization in T-lymphocyte secretory granule|protein localization in T cell secretory granule													biological_process											owl:Class	
GO:0060976	biolink:NamedThing	coronary vasculature development	The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.	got7fsn_ti	heart blood vessel development|cardiac blood vessel development|heart vasculature development|coronary blood vessel development|cardiac vasculature development						dph	2009-10-06T12:15:23Z						biological_process											owl:Class	
GO:0070864	biolink:NamedThing	sperm individualization complex	A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.	got7fsn_ti							mah	2009-08-19T01:25:33Z						cellular_component											owl:Class	
GO:1990413	biolink:NamedThing	eyespot apparatus	A small pigmented organelle used in single-celled organisms to detect light.	got7fsn_ti	stigma|eyespot						cjm	2014-07-03T21:26:24Z						cellular_component											owl:Class	
GO:0015483	biolink:NamedThing	long-chain fatty acid transporting porin activity	Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	got7fsn_ti												TC:1.B.9.1.1		molecular_function											owl:Class	
GO:0015909	biolink:NamedThing	long-chain fatty acid transport	The directed movement of long-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti														biological_process											owl:Class	
GO:1903741	biolink:NamedThing	negative regulation of phosphatidate phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity.	got7fsn_ti	down regulation of phosphatic acid phosphohydrolase activity|down regulation of acid phosphatidyl phosphatase activity|down-regulation of acid phosphatidyl phosphatase activity|down-regulation of phosphatidate phosphohydrolase activity|down regulation of phosphatidate phosphohydrolase activity|down-regulation of phosphatidate phosphatase activity|down-regulation of 3-sn-phosphatidate phosphohydrolase activity|down regulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of acid phosphatidyl phosphatase activity|downregulation of acid phosphatidyl phosphatase activity|down regulation of phosphatic acid phosphatase activity|downregulation of 3-sn-phosphatidate phosphohydrolase activity|inhibition of phosphatidic acid phosphatase activity|negative regulation of phosphatic acid phosphatase activity|inhibition of 3-sn-phosphatidate phosphohydrolase activity|inhibition of phosphatic acid phosphatase activity|negative regulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of phosphatidic acid phosphatase activity|down-regulation of phosphatic acid phosphohydrolase activity|downregulation of phosphatic acid phosphatase activity|inhibition of phosphatidate phosphohydrolase activity|downregulation of phosphatidate phosphatase activity|down-regulation of phosphatidic acid phosphatase activity|down regulation of phosphatidate phosphatase activity|inhibition of acid phosphatidyl phosphatase activity|negative regulation of phosphatidate phosphohydrolase activity|down regulation of phosphatidic acid phosphatase activity|inhibition of phosphatic acid phosphohydrolase activity|negative regulation of phosphatic acid phosphohydrolase activity|down-regulation of phosphatic acid phosphatase activity|downregulation of phosphatidate phosphohydrolase activity|downregulation of phosphatidic acid phosphatase activity|inhibition of phosphatidate phosphatase activity|downregulation of phosphatic acid phosphohydrolase activity						tb	2014-12-11T23:37:54Z						biological_process											owl:Class	
GO:0071072	biolink:NamedThing	negative regulation of phospholipid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.	got7fsn_ti	negative regulation of phospholipid biosynthesis|negative regulation of phospholipid formation|negative regulation of phospholipid synthesis|down regulation of phospholipid biosynthetic process|negative regulation of phospholipid anabolism|down-regulation of phospholipid biosynthetic process|downregulation of phospholipid biosynthetic process|inhibition of phospholipid biosynthetic process						mah	2009-11-04T03:14:08Z						biological_process											owl:Class	
GO:2001205	biolink:NamedThing	negative regulation of osteoclast development	Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.	got7fsn_ti	negative regulation of osteoclast cell development						yaf	2011-11-10T10:59:06Z						biological_process											owl:Class	
GO:0021744	biolink:NamedThing	dorsal motor nucleus of vagus nerve development	The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0048273	biolink:NamedThing	mitogen-activated protein kinase p38 binding	Binding to mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.	got7fsn_ti	MAPK p38 binding													molecular_function											owl:Class	
GO:1905349	biolink:NamedThing	ciliary transition zone assembly	The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.	got7fsn_ti	cilium transition zone formation|cilial transition zone formation|cilial transition zone assembly|ciliary transition zone formation|cilium transition zone assembly						pr	2016-08-04T14:49:43Z						biological_process											owl:Class	
GO:0006794	biolink:NamedThing	phosphorus utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0006793	biolink:NamedThing	phosphorus metabolic process	The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).	got7fsn_ti	phosphorus metabolism													biological_process											owl:Class	
GO:0044734	biolink:NamedThing	envenomation resulting in positive regulation of acid-sensing ion channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.	got7fsn_ti	envenomation resulting in positive regulation of ASIC channel activity in other organism						jl	2012-11-06T16:02:01Z						biological_process											owl:Class	
GO:0044739	biolink:NamedThing	positive regulation of acid-sensing ion channel in other organism	Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism.	got7fsn_ti	positive regulation of ASIC channel in other organism						jl	2012-11-06T16:56:27Z						biological_process											owl:Class	
GO:0071439	biolink:NamedThing	clathrin complex	A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.	got7fsn_ti	clathrin triskelion						mah	2009-12-16T03:17:58Z						cellular_component											owl:Class	
GO:1901400	biolink:NamedThing	positive regulation of transforming growth factor beta3 activation	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation.	got7fsn_ti	positive regulation of TGF-beta 3 activation|up regulation of transforming growth factor beta3 activation|positive regulation of TGFB3 activation|activation of TGF-beta 3 activation|up regulation of TGFB3 activation|up-regulation of TGFbeta 3 activation|upregulation of TGFbeta 3 activation|upregulation of transforming growth factor beta3 activation|up-regulation of transforming growth factor beta3 activation|activation of TGFbeta 3 activation|up regulation of TGF-beta 3 activation|up-regulation of TGF-beta 3 activation|positive regulation of TGFbeta 3 activation|up-regulation of TGFB3 activation|up regulation of TGFbeta 3 activation|upregulation of TGF-beta 3 activation|activation of TGFB3 activation|upregulation of TGFB3 activation|activation of transforming growth factor beta3 activation						bf	2012-10-01T10:50:49Z						biological_process											owl:Class	
GO:0032907	biolink:NamedThing	transforming growth factor beta3 production	The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	TGF-B3 production|TGFB3 production|transforming growth factor-beta3 production													biological_process											owl:Class	
GO:0072127	biolink:NamedThing	renal capsule development	The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.	got7fsn_ti							mah	2010-02-22T02:02:55Z						biological_process											owl:Class	
GO:1905392	biolink:NamedThing	plant organ morphogenesis	The developmental process by which a plant organ is generated and organized.	got7fsn_ti							tb	2016-08-24T00:21:19Z						biological_process											owl:Class	
GO:0022625	biolink:NamedThing	cytosolic large ribosomal subunit	The large subunit of a ribosome located in the cytosol.	got7fsn_ti	eukaryotic ribosomal LSU|50S ribosomal subunit|60S ribosomal subunit|prokaryotic large ribosomal subunit										GO:0005842|GO:0030872|GO:0009282|GO:0030498			cellular_component											owl:Class	
GO:0022626	biolink:NamedThing	cytosolic ribosome	A ribosome located in the cytosol.	got7fsn_ti	80S ribosome|70S ribosome										GO:0009281|GO:0005830|GO:0030871			cellular_component											owl:Class	
GO:0000464	biolink:NamedThing	endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs.	got7fsn_ti	endonucleolytic cleavage at A3													biological_process											owl:Class	
GO:0061098	biolink:NamedThing	positive regulation of protein tyrosine kinase activity	Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.	got7fsn_ti							dph	2010-04-26T02:34:53Z						biological_process											owl:Class	
GO:0005663	biolink:NamedThing	DNA replication factor C complex	A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides.	got7fsn_ti	activator 1 complex|RFC complex													cellular_component											owl:Class	
GO:0005657	biolink:NamedThing	replication fork	The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.	got7fsn_ti	replication focus											Wikipedia:Replication_fork		cellular_component											owl:Class	
GO:0034348	biolink:NamedThing	type III interferon receptor activity	Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	interferon-lambda receptor activity				Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.									molecular_function											owl:Class	
GO:0005814	biolink:NamedThing	centriole	A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.	got7fsn_ti	daughter centriole|mother centriole				In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.							NIF_Subcellular:sao95019936|Wikipedia:Centriole		cellular_component											owl:Class	
GO:0099608	biolink:NamedThing	regulation of action potential firing pattern	Any process that regulates the temporal pattern of a sequence of action potentials in a neuron.	got7fsn_ti	spike train sculpting													biological_process											owl:Class	
GO:1904442	biolink:NamedThing	negative regulation of thyroid gland epithelial cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation.	got7fsn_ti	down regulation of Hurthle cell proliferation|inhibition of Hurthle cell proliferation|downregulation of thyroid follicular cell proliferation|down regulation of thyroid follicular cell proliferation|down-regulation of Hurthle cell proliferation|negative regulation of thyroid follicular cell proliferation|inhibition of thyroid follicular cell proliferation|negative regulation of Hurthle cell proliferation|inhibition of thyroid gland epithelial cell proliferation|down regulation of thyroid gland epithelial cell proliferation|down-regulation of thyroid gland epithelial cell proliferation|downregulation of thyroid gland epithelial cell proliferation|downregulation of Hurthle cell proliferation|down-regulation of thyroid follicular cell proliferation						sl	2015-07-06T15:41:15Z						biological_process											owl:Class	
NCBITaxon:32525	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097754	biolink:NamedThing	clathrin-mediated membrane bending	A membrane bending process mediated by clathrin.	got7fsn_ti							pr	2017-01-25T16:38:42Z						biological_process											owl:Class	
GO:0015124	biolink:NamedThing	allantoate transmembrane transporter activity	Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.	got7fsn_ti														molecular_function											owl:Class	
GO:0015719	biolink:NamedThing	allantoate transport	The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	allantoin/allantoate transport													biological_process											owl:Class	
GO:0046814	biolink:NamedThing	coreceptor-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface.	got7fsn_ti	virion attachment, binding of host cell surface coreceptor													biological_process											owl:Class	
GO:0039706	biolink:NamedThing	co-receptor binding	Binding to a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell.	got7fsn_ti							bf	2013-11-25T14:41:42Z						molecular_function											owl:Class	
GO:0048619	biolink:NamedThing	embryonic hindgut morphogenesis	The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0043514	biolink:NamedThing	interleukin-12 complex	A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.	got7fsn_ti	IL12A|IL12B|IL-12 complex|p35|p40				Note that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain.									cellular_component											owl:Class	
GO:0032437	biolink:NamedThing	cuticular plate	A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.	got7fsn_ti														cellular_component											owl:Class	
CL:0000855	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140638	biolink:NamedThing	small ribosomal subunit processing complex	A small heterodimeric protein complex that is required during early maturation of nascent 40S ribosomal subunits. The complex has endonuclease activity, it interacts with the small ribosomal subunit pre-rRNA and cleave it it to produce the mature 18S (or small ribosomal subunit) rRNA. In S. cerevisiae it is composed of Rcl1p and Bms1p.	got7fsn_ti	small ribosomal subunit maturation complex	https://github.com/geneontology/go-ontology/issues/15290					pg	2021-04-21T08:07:11Z						cellular_component											owl:Class	
GO:0042274	biolink:NamedThing	ribosomal small subunit biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.	got7fsn_ti	ribosomal small subunit biogenesis and assembly													biological_process											owl:Class	
GO:0015603	biolink:NamedThing	iron chelate transmembrane transporter activity	Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.	got7fsn_ti														molecular_function											owl:Class	
GO:0033214	biolink:NamedThing	siderophore-dependent iron import into cell	A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors.	got7fsn_ti	iron chelate transport|iron assimilation by capture and transport|iron assimilation by chelation and transport										GO:0015688|GO:0033213			biological_process											owl:Class	
GO:0060997	biolink:NamedThing	dendritic spine morphogenesis	The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	got7fsn_ti							dph	2010-01-20T09:09:57Z						biological_process											owl:Class	
GO:0060996	biolink:NamedThing	dendritic spine development	The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	got7fsn_ti							dph	2010-01-20T09:06:33Z						biological_process											owl:Class	
GO:0035511	biolink:NamedThing	oxidative DNA demethylation	Removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.	got7fsn_ti							bf	2010-04-30T02:22:44Z						biological_process											owl:Class	
GO:0008407	biolink:NamedThing	chaeta morphogenesis	The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.	got7fsn_ti	bristle morphogenesis													biological_process											owl:Class	
GO:0014802	biolink:NamedThing	terminal cisterna	The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release.	got7fsn_ti												Wikipedia:Terminal_cisterna		cellular_component											owl:Class	
GO:0007356	biolink:NamedThing	thorax and anterior abdomen determination	Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.	got7fsn_ti														biological_process											owl:Class	
GO:0007354	biolink:NamedThing	zygotic determination of anterior/posterior axis, embryo	The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.	got7fsn_ti														biological_process											owl:Class	
GO:1990121	biolink:NamedThing	H-NS complex	A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA.	got7fsn_ti	histone-like protein H-NS complex|DNA-binding protein H-NS complex						bhm	2013-06-12T10:08:31Z						cellular_component											owl:Class	
GO:0015216	biolink:NamedThing	purine nucleotide transmembrane transporter activity	Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015865	biolink:NamedThing	purine nucleotide transport	The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0036449	biolink:NamedThing	microtubule minus-end	The end of a microtubule that does not preferentially grow (polymerize).	got7fsn_ti	microtubule minus end						bf	2013-10-31T13:26:51Z						cellular_component											owl:Class	
GO:1903105	biolink:NamedThing	negative regulation of insulin receptor signaling pathway involved in determination of adult lifespan	Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.	got7fsn_ti	negative regulation of insulin receptor signaling pathway of determination of adult lifespan|downregulation of daf-2 receptor signaling pathway of determination of adult lifespan|inhibition of insulin receptor signalling pathway of determination of adult lifespan|downregulation of insulin receptor signalling pathway of determination of adult lifespan|down regulation of daf-2 receptor signaling pathway of determination of adult lifespan|negative regulation of insulin receptor signalling pathway of determination of adult lifespan|down-regulation of insulin receptor signaling pathway of determination of adult lifespan|down regulation of insulin receptor signaling pathway of determination of adult lifespan|down regulation of insulin receptor signalling pathway of determination of adult lifespan|inhibition of daf-2 receptor signaling pathway of determination of adult lifespan|negative regulation of daf-2 receptor signaling pathway of determination of adult lifespan|downregulation of insulin receptor signaling pathway involved in determination of adult lifespan|downregulation of insulin receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signaling pathway involved in determination of adult lifespan|inhibition of insulin receptor signaling pathway of determination of adult lifespan|down regulation of insulin receptor signaling pathway involved in determination of adult lifespan|down-regulation of daf-2 receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signalling pathway of determination of adult lifespan|inhibition of insulin receptor signaling pathway involved in determination of adult lifespan						kmv	2014-06-05T20:56:12Z						biological_process											owl:Class	
GO:0035763	biolink:NamedThing	dorsal motor nucleus of vagus nerve structural organization	The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	dorsal motor nucleus of vagus nerve structural organisation						bf	2011-03-29T02:47:56Z						biological_process											owl:Class	
GO:0035762	biolink:NamedThing	dorsal motor nucleus of vagus nerve morphogenesis	The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.	got7fsn_ti							bf	2011-03-29T02:47:18Z						biological_process											owl:Class	
GO:0010599	biolink:NamedThing	production of lsiRNA involved in RNA interference	Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions.	got7fsn_ti	RNA interference, production of lsiRNA													biological_process											owl:Class	
GO:0016246	biolink:NamedThing	RNA interference	The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.	got7fsn_ti	RNAi|posttranscriptional gene silencing by siRNA				Note that this term refers specifically to posttranscriptional mechanisms by which small interfering RNAs down-regulate gene expression. Also consider annotating to other descendants of 'gene silencing by RNA ; GO:0031047'.							Wikipedia:RNA_interference		biological_process											owl:Class	
GO:0034456	biolink:NamedThing	UTP-C complex	A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p.	got7fsn_ti	Rrp7p-containing subcomplex of 90S preribosome				Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.									cellular_component											owl:Class	
GO:0007066	biolink:NamedThing	female meiosis sister chromatid cohesion	The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female.	got7fsn_ti														biological_process											owl:Class	
GO:0061011	biolink:NamedThing	hepatic duct development	The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.	got7fsn_ti							dph	2010-01-22T09:44:39Z						biological_process											owl:Class	
GO:0016543	biolink:NamedThing	male courtship behavior, orientation prior to leg tapping and wing vibration	The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster.	got7fsn_ti	male courtship behaviour, orientation|male courtship behavior, orientation|male courtship behaviour, orientation prior to leg tapping and wing vibration													biological_process											owl:Class	
GO:0007133	biolink:NamedThing	meiotic anaphase I	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0043220	biolink:NamedThing	Schmidt-Lanterman incisure	Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier.	got7fsn_ti	Schmidt-Lanterman cleft										GO:0044287	NIF_Subcellular:sao254777664		cellular_component											owl:Class	
GO:0043218	biolink:NamedThing	compact myelin	The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs.	got7fsn_ti	oligodendrocyte compact myelin|Schwann cell compact myelin											NIF_Subcellular:sao1123256993		cellular_component											owl:Class	
GO:0048742	biolink:NamedThing	regulation of skeletal muscle fiber development	Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	got7fsn_ti	regulation of skeletal myofibre development|regulation of skeletal muscle fibre development|regulation of skeletal myofiber development													biological_process											owl:Class	
NCBITaxon:38254	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090658	biolink:NamedThing	cone matrix sheath	A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments.	got7fsn_ti							tb	2015-07-15T13:35:32Z						cellular_component											owl:Class	
GO:0071061	biolink:NamedThing	alpha6-beta4 integrin-CD151 complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.	got7fsn_ti	ITGA6-ITGB4-CD151 complex						mah	2009-11-03T04:02:37Z						cellular_component											owl:Class	
GO:0004651	biolink:NamedThing	polynucleotide 5'-phosphatase activity	Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.	got7fsn_ti	5'-polynucleotidase activity|polynucleotide 5'-triphosphatase activity|polynucleotide 5'-phosphohydrolase activity											RHEA:11008|EC:3.1.3.33|MetaCyc:POLYNUCLEOTIDE-5-PHOSPHATASE-RXN|Reactome:R-HSA-77078		molecular_function											owl:Class	
GO:0098507	biolink:NamedThing	polynucleotide 5' dephosphorylation	The process of removing one or more phosphate groups from the 5' end of a polynucleotide.	got7fsn_ti														biological_process											owl:Class	
GO:0061256	biolink:NamedThing	mesonephric glomerular visceral epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.	got7fsn_ti							dph	2010-08-30T02:03:38Z						biological_process											owl:Class	
GO:0062151	biolink:NamedThing	catalase complex	A protein-containing complex that is capable of catalase activity.	got7fsn_ti							dph	2019-09-17T12:18:02Z						cellular_component											owl:Class	
GO:0061692	biolink:NamedThing	cellular detoxification of hydrogen peroxide	Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.	got7fsn_ti							dph	2015-05-05T12:46:20Z						biological_process											owl:Class	
GO:0043584	biolink:NamedThing	nose development	The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).	got7fsn_ti	nasus development													biological_process											owl:Class	
GO:0002622	biolink:NamedThing	regulation of B cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.	got7fsn_ti	regulation of B-cell antigen processing and presentation|regulation of B-lymphocyte antigen processing and presentation|regulation of B lymphocyte antigen processing and presentation													biological_process											owl:Class	
GO:0003151	biolink:NamedThing	outflow tract morphogenesis	The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.	got7fsn_ti							tb	2009-09-22T07:59:24Z						biological_process											owl:Class	
GO:0062128	biolink:NamedThing	MutSgamma complex	A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5.	got7fsn_ti	Msh4-Msh5 complex						dph	2019-06-04T14:48:15Z						cellular_component											owl:Class	
GO:0048371	biolink:NamedThing	lateral mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell.	got7fsn_ti	lateral mesoderm cell differentiation|lateral plate mesoderm cell differentiation|lateral plate mesodermal cell differentiation													biological_process											owl:Class	
GO:1900224	biolink:NamedThing	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry.	got7fsn_ti	upregulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|positive regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|positive regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|activation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|activation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|activation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|positive regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|up-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry						vk	2012-03-22T02:30:13Z						biological_process											owl:Class	
GO:1990563	biolink:NamedThing	extracellular exosome complex	A protein complex that is wholly or partially contained within the lumen or membrane of the extracellular vesicular exosome.	got7fsn_ti	exosome complex|extracellular vesicular exosome complex				An example of this is SCD1 in human (UniProt symbol P18827) in PMID:22660413 (inferred from physical interaction).		bhm	2014-11-25T16:35:53Z						cellular_component											owl:Class	
GO:0051087	biolink:NamedThing	chaperone binding	Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.	got7fsn_ti	co-chaperonin activity|chaperone protein binding|co-chaperone activity													molecular_function											owl:Class	
GO:0099500	biolink:NamedThing	vesicle fusion to plasma membrane	Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.	got7fsn_ti														biological_process											owl:Class	
GO:0106037	biolink:NamedThing	apicomedial cortex	The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell.	got7fsn_ti	medioapical cortex						hjd	2017-07-12T16:59:52Z						cellular_component											owl:Class	
GO:0045179	biolink:NamedThing	apical cortex	The region that lies just beneath the plasma membrane on the apical edge of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0007199	biolink:NamedThing	G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).	got7fsn_ti	GPCR signaling pathway via cGMP second messenger|guanylate cyclase-activating G-protein coupled receptor signaling pathway|G-protein signalling, coupled to cGMP nucleotide second messenger|G protein signalling, coupled to cGMP nucleotide second messenger|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|G protein signaling, coupled to cGMP nucleotide second messenger|G-protein signaling, coupled to cGMP nucleotide second messenger|GPCR signaling pathway via activation of guanylate cyclase activity													biological_process											owl:Class	
GO:0031284	biolink:NamedThing	positive regulation of guanylate cyclase activity	Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity.	got7fsn_ti	stimulation of guanylate cyclase activity|upregulation of guanylate cyclase activity|up-regulation of guanylate cyclase activity|activation of guanylate cyclase activity|up regulation of guanylate cyclase activity													biological_process											owl:Class	
GO:0010440	biolink:NamedThing	stomatal lineage progression	The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex.	got7fsn_ti														biological_process											owl:Class	
GO:0030343	biolink:NamedThing	vitamin D3 25-hydroxylase activity	Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O.	got7fsn_ti	cholecalciferol 25-hydroxylase activity											Reactome:R-HSA-5602147|MetaCyc:RXN-9829|Reactome:R-HSA-209845|RHEA:32903		molecular_function											owl:Class	
GO:0036378	biolink:NamedThing	calcitriol biosynthetic process from calciol	Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.	got7fsn_ti	vitamin D3 activation|calcitriol biosynthesis from calciol|1alpha,25-dihydroxycholecalciferol biosynthesis|1alpha,25-dihydroxyvitamin D3 biosynthesis|1alpha,25(OH)2D3 biosynthesis						bf	2013-05-15T11:46:08Z						biological_process											owl:Class	
GO:0045691	biolink:NamedThing	regulation of embryo sac central cell differentiation	Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation.	got7fsn_ti	regulation of female gametophyte central cell differentiation													biological_process											owl:Class	
GO:0009559	biolink:NamedThing	embryo sac central cell differentiation	The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell.	got7fsn_ti	female gametophyte central cell differentiation|embryo sac endosperm mother cell differentiation													biological_process											owl:Class	
GO:0035318	biolink:NamedThing	imaginal disc-derived wing hair outgrowth	Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.	got7fsn_ti	wing hair outgrowth|wing prehair outgrowth													biological_process											owl:Class	
GO:0035317	biolink:NamedThing	imaginal disc-derived wing hair organization	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.	got7fsn_ti	imaginal disc-derived wing hair organization and biogenesis|wing hair organization and biogenesis|wing hair organisation|wing trichome organization and biogenesis				See also the fly_anatomy.ontology term 'wing hair ; FBbt:00004340'.									biological_process											owl:Class	
GO:0060914	biolink:NamedThing	heart formation	The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.	got7fsn_ti	cardiogenesis						dph	2009-09-17T09:02:13Z						biological_process											owl:Class	
GO:0071094	biolink:NamedThing	alpha6-beta4 integrin-CD9 complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.	got7fsn_ti	ITGA6-ITGB4-CD9 complex						mah	2009-11-06T04:47:44Z						cellular_component											owl:Class	
GO:0071255	biolink:NamedThing	Cvt vesicle assembly	A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).	got7fsn_ti	Cvt vesicle formation|cytoplasm-to-vacuole targetin vesicle assembly|Cvt vesicle biosynthesis|cytoplasm to vacuole targeting vesicle assembly						mah	2009-12-04T10:39:50Z						biological_process											owl:Class	
GO:0032258	biolink:NamedThing	cytoplasm to vacuole transport by the Cvt pathway	A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.	got7fsn_ti	protein localization by the Cvt pathway|cytoplasm to vacuole targeting|cytoplasm-to-vacuole targeting													biological_process											owl:Class	
GO:0003025	biolink:NamedThing	regulation of systemic arterial blood pressure by baroreceptor feedback	The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.	got7fsn_ti	baroreceptor regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0003342	biolink:NamedThing	proepicardium development	The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.	got7fsn_ti							dph	2009-12-01T10:30:17Z						biological_process											owl:Class	
GO:0003343	biolink:NamedThing	septum transversum development	The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.	got7fsn_ti							dph	2009-12-01T10:40:17Z						biological_process											owl:Class	
GO:0030690	biolink:NamedThing	Noc1p-Noc2p complex	A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.	got7fsn_ti					Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.									cellular_component											owl:Class	
GO:0030687	biolink:NamedThing	preribosome, large subunit precursor	A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.	got7fsn_ti	66S preribosome				Note that this complex is 66S in Saccharomyces.									cellular_component											owl:Class	
GO:0045261	biolink:NamedThing	proton-transporting ATP synthase complex, catalytic core F(1)	The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled.	got7fsn_ti	hydrogen-transporting ATP synthase, F1 sector													cellular_component											owl:Class	
GO:0000796	biolink:NamedThing	condensin complex	A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis.	got7fsn_ti	condensin I complex|13S condensin complex|condensin core heterodimer|SMC complex|Smc2-Smc4 complex|nuclear condensin complex|8S condensin complex	https://github.com/geneontology/go-ontology/issues/12832									GO:0061814|GO:0000797|GO:0008621|GO:0000799|GO:0005676|GO:0008620			cellular_component											owl:Class	
GO:0006352	biolink:NamedThing	DNA-templated transcription, initiation	Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.	got7fsn_ti	DNA-dependent RNA polymerase complex assembly at promoter|initiation of DNA-dependent transcription|DNA-dependent transcription, initiation|initiation of transcription, DNA-dependent|transcription initiation, DNA-dependent|transcription initiation factor activity				Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.									biological_process											owl:Class	
GO:0097189	biolink:NamedThing	apoptotic body	A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um.	got7fsn_ti	apoptotic bleb|apoptotic vesicle						pr	2011-11-22T08:05:20Z						cellular_component											owl:Class	
GO:1903773	biolink:NamedThing	negative regulation of viral budding via host ESCRT complex	Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex.	got7fsn_ti	down regulation of viral budding through the ESCRT machinery|inhibition of viral budding via host ESCRT complex|down-regulation of viral budding via host ESCRT complex|downregulation of viral budding through the ESCRT machinery|inhibition of viral budding through the ESCRT machinery|down regulation of viral budding via host ESCRT complex|down-regulation of viral budding through the ESCRT machinery|downregulation of viral budding via host ESCRT complex|negative regulation of viral budding through the ESCRT machinery						als	2015-01-06T16:20:53Z						biological_process											owl:Class	
GO:0061809	biolink:NamedThing	NAD+ nucleotidase, cyclic ADP-ribose generating	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity.	got7fsn_ti							dph	2016-11-11T13:14:13Z				MetaCyc:NADNUCLEOSID-RXN|EC:3.2.2.6		molecular_function											owl:Class	
GO:0002808	biolink:NamedThing	regulation of antibacterial peptide biosynthetic process	Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0051780	biolink:NamedThing	behavioral response to nutrient	Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus.	got7fsn_ti	behavioural response to nutrient													biological_process											owl:Class	
GO:0097495	biolink:NamedThing	H-NS-Hha complex	A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes.	got7fsn_ti							pr	2013-08-08T14:37:33Z						cellular_component											owl:Class	
GO:0044023	biolink:NamedThing	histone kinase activity (H4-S1 specific)	Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H4.	got7fsn_ti	histone-serine kinase activity (H4-S1 specific)|histone serine kinase activity (H4-S1 specific)													molecular_function											owl:Class	
GO:0021842	biolink:NamedThing	chemorepulsion involved in interneuron migration from the subpallium to the cortex	The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex.	got7fsn_ti	negative chemotaxis involved in interneuron migration from the subpallium to the cortex													biological_process											owl:Class	
GO:0021840	biolink:NamedThing	directional guidance of interneurons involved in migration from the subpallium to the cortex	The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0048838	biolink:NamedThing	release of seed from dormancy	The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release.	got7fsn_ti														biological_process											owl:Class	
GO:0110025	biolink:NamedThing	DNA strand resection involved in replication fork processing	The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing.	got7fsn_ti							kmv	2017-07-05T14:43:36Z						biological_process											owl:Class	
GO:0140617	biolink:NamedThing	transvection	An epigenetic regulation of transcription by physical interaction between a cis-acting element (enhancer, silencer) of one allele on one chromosome and the promoter of the corresponding allele on the homologous chromosome. Transvection can lead to either gene activation or repression.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21038					pg	2021-03-08T18:30:47Z						biological_process											owl:Class	
NCBITaxon:7147	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000123	biolink:NamedThing	histone acetyltransferase complex	A protein complex that possesses histone acetyltransferase activity.	got7fsn_ti	histone acetylase complex				Note that this term represents a location, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone acetyltransferase activity ; GO:0004402'.									cellular_component											owl:Class	
GO:0022015	biolink:NamedThing	radial glial cell division in pallium	The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.	got7fsn_ti														biological_process											owl:Class	
GO:0031429	biolink:NamedThing	box H/ACA snoRNP complex	A box H/ACA RNP complex that is located in the nucleolus.	got7fsn_ti	box H/ACA small nucleolar ribonucleoprotein complex|box H/ACA snoRNP pseudouridylase complex													cellular_component											owl:Class	
GO:0019070	biolink:NamedThing	viral genome maturation	The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes.	got7fsn_ti														biological_process											owl:Class	
GO:0019068	biolink:NamedThing	virion assembly	A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.	got7fsn_ti	phage assembly|viral assembly|viral particle assembly|virus particle assembly|virus assembly|virion assembly and maintenance|virion organization|bacteriophage assembly										GO:0042963			biological_process											owl:Class	
GO:0002071	biolink:NamedThing	glandular epithelial cell maturation	The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.	got7fsn_ti														biological_process											owl:Class	
GO:0002068	biolink:NamedThing	glandular epithelial cell development	The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.	got7fsn_ti														biological_process											owl:Class	
GO:0072189	biolink:NamedThing	ureter development	The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.	got7fsn_ti							mah	2010-03-01T01:44:14Z						biological_process											owl:Class	
GO:0072001	biolink:NamedThing	renal system development	The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.	got7fsn_ti	urinary system development|urinary tract development						mah	2010-01-25T10:31:00Z						biological_process											owl:Class	
GO:0006791	biolink:NamedThing	sulfur utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism.	got7fsn_ti	sulphur utilization													biological_process											owl:Class	
GO:0042600	biolink:NamedThing	egg chorion	A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.	got7fsn_ti					Note that this term does not refer to the extraembryonic membrane surrounding the embryo of amniote vertebrates as this is an anatomical structure and is therefore not covered by GO.									cellular_component											owl:Class	
GO:0035735	biolink:NamedThing	intraciliary transport involved in cilium assembly	The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.	got7fsn_ti	intraciliary transport involved in cilium morphogenesis|intraflagellar transport involved in cilium morphogenesis|intraflagellar transport						bf	2011-03-17T10:55:42Z				Reactome:R-HSA-5620924.2		biological_process											owl:Class	
GO:0017143	biolink:NamedThing	insecticide metabolic process	The chemical reactions and pathways involving insecticides, chemicals used to kill insects.	got7fsn_ti	insecticide metabolism										GO:0017138			biological_process											owl:Class	
GO:0098698	biolink:NamedThing	postsynaptic specialization assembly	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.	got7fsn_ti							dos	2017-04-04T17:22:01Z						biological_process											owl:Class	
GO:0099068	biolink:NamedThing	postsynapse assembly	The aggregation, arrangement and bonding together of a set of components to form a postsynapse.	got7fsn_ti	postsynapse biogenesis													biological_process											owl:Class	
GO:0099561	biolink:NamedThing	synaptic membrane adhesion to extracellular matrix	The binding of a synaptic membrane to the extracellular matrix via adhesion molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0030584	biolink:NamedThing	sporocarp development	The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea.	got7fsn_ti	fruiting body development													biological_process											owl:Class	
GO:0140243	biolink:NamedThing	regulation of translation at synapse	Any process that regulates translation occurring at the synapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/210			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:38:26Z						biological_process											owl:Class	
GO:0061287	biolink:NamedThing	mesonephric capsule formation	The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	got7fsn_ti							dph	2010-09-02T01:55:03Z						biological_process											owl:Class	
GO:0097619	biolink:NamedThing	PTEX complex	A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components.	got7fsn_ti	Plasmodium translocon of exported proteins						pr	2014-07-29T16:05:32Z						cellular_component											owl:Class	
GO:0062003	biolink:NamedThing	negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.	got7fsn_ti							dph	2018-02-26T13:23:20Z						biological_process											owl:Class	
GO:0002502	biolink:NamedThing	peptide antigen assembly with MHC class I protein complex	The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0072034	biolink:NamedThing	renal vesicle induction	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.	got7fsn_ti	positive regulation of nephron formation|nephron induction						mah	2010-01-25T02:58:18Z						biological_process											owl:Class	
GO:0071067	biolink:NamedThing	alphav-beta3 integrin-ADAM23 complex	A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.	got7fsn_ti	ITGAV-ITGB3-ADAM23 complex						mah	2009-11-03T04:04:40Z						cellular_component											owl:Class	
GO:1990303	biolink:NamedThing	UBR1-RAD6 ubiquitin ligase complex	A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes.	got7fsn_ti	UBR1-RAD6 complex				This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).		bhm	2014-03-03T21:43:49Z						cellular_component											owl:Class	
GO:0098584	biolink:NamedThing	host cell synaptic vesicle	A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.	got7fsn_ti							dos	2014-01-24T13:14:13Z						cellular_component											owl:Class	
GO:0044221	biolink:NamedThing	host cell synapse	The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication.	got7fsn_ti							jl	2009-11-12T03:03:59Z						cellular_component											owl:Class	
GO:0031597	biolink:NamedThing	cytosolic proteasome complex	A proteasome complex found in the cytosol of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0060203	biolink:NamedThing	clathrin-sculpted glutamate transport vesicle membrane	The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle.	got7fsn_ti	clathrin sculpted glutamate transport vesicle membrane|clathrin sculpted glutamate constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0055045	biolink:NamedThing	antipodal cell degeneration	The process in which the antipodal cells undergo programmed cell death.	got7fsn_ti														biological_process											owl:Class	
GO:0009336	biolink:NamedThing	sulfate adenylyltransferase complex (ATP)	An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP.	got7fsn_ti	sulphate adenylyltransferase complex (ATP)													cellular_component											owl:Class	
GO:0070550	biolink:NamedThing	rDNA condensation	The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.	got7fsn_ti	rDNA packaging													biological_process											owl:Class	
GO:1990061	biolink:NamedThing	bacterial degradosome	The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase.	got7fsn_ti							bhm	2013-03-20T13:51:49Z						cellular_component											owl:Class	
GO:0003066	biolink:NamedThing	positive regulation of heart rate by norepinephrine	The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.	got7fsn_ti	norepinephrine cardiac chronotropy|positive regulation of heart rate by adrenaline|positive regulation of heart contraction rate by norepinephrine|noradrenaline cardiac chronotropy|noradrenaline regulation of the rate of heart muscle contraction													biological_process											owl:Class	
GO:0021652	biolink:NamedThing	rhombomere 1 formation	The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0021651	biolink:NamedThing	rhombomere 1 morphogenesis	The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0021679	biolink:NamedThing	cerebellar molecular layer development	The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	got7fsn_ti														biological_process											owl:Class	
GO:0021879	biolink:NamedThing	forebrain neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0000813	biolink:NamedThing	ESCRT I complex	An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.	got7fsn_ti	endosomal sorting complex required for transport													cellular_component											owl:Class	
GO:0030895	biolink:NamedThing	apolipoprotein B mRNA editing enzyme complex	Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).	got7fsn_ti	apoB mRNA editing enzyme complex|APOBEC													cellular_component											owl:Class	
GO:0051838	biolink:NamedThing	cytolysis by host of symbiont cells	The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0052337	biolink:NamedThing	modification by host of symbiont membrane	The process in which an organism effects a change in the structure or function of a symbiont cellular membrane. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by host of symbiont cell membrane													biological_process											owl:Class	
GO:0004713	biolink:NamedThing	protein tyrosine kinase activity	Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.	got7fsn_ti	protein-tyrosine kinase activity										GO:0004718	Reactome:R-HSA-5654545|Reactome:R-HSA-445076|Reactome:R-HSA-2130194|Reactome:R-HSA-5655301|Reactome:R-HSA-9006323|Reactome:R-HSA-983707|Reactome:R-HSA-5218809|Reactome:R-HSA-9706344|Reactome:R-HSA-5654151|Reactome:R-HSA-9665705|Reactome:R-HSA-9625487|Reactome:R-HSA-5357429|Reactome:R-HSA-388833|Reactome:R-HSA-170156|Reactome:R-HSA-1433418|Reactome:R-HSA-8876246|Reactome:R-HSA-212710|Reactome:R-HSA-202174|Reactome:R-HSA-190429|Reactome:R-HSA-190388|Reactome:R-HSA-389083|Reactome:R-HSA-9021609|Reactome:R-HSA-9037040|Reactome:R-HSA-9032532|Reactome:R-HSA-8874078|Reactome:R-HSA-8853325|Reactome:R-HSA-1963581|Reactome:R-HSA-8937728|Reactome:R-HSA-909730|Reactome:R-HSA-1470009|Reactome:R-HSA-190385|Reactome:R-HSA-399934|Reactome:R-HSA-1248694|Reactome:R-HSA-8853315|Reactome:R-HSA-9032601|Reactome:R-HSA-372693|Reactome:R-HSA-879907|Reactome:R-HSA-2730860|Reactome:R-HSA-8874080|Reactome:R-HSA-2586555|Reactome:R-HSA-8857555|Reactome:R-HSA-9613023|Reactome:R-HSA-3928627|Reactome:R-HSA-1839110|RHEA:10596|Reactome:R-HSA-9029151|Reactome:R-HSA-418163|Reactome:R-HSA-202216|Reactome:R-HSA-8851890|Reactome:R-HSA-1433488|Reactome:R-HSA-2029459|Reactome:R-HSA-9604767|Reactome:R-HSA-452122|Reactome:R-HSA-5655268|Reactome:R-HSA-8948143|Reactome:R-HSA-5654631|Reactome:R-HSA-2012073|Reactome:R-HSA-909732|Reactome:R-HSA-8847977|Reactome:R-HSA-8848436|Reactome:R-HSA-183058|Reactome:R-HSA-389762|Reactome:R-HSA-2395439|Reactome:R-HSA-1250195|Reactome:R-HSA-5218642|Reactome:R-HSA-1433454|Reactome:R-HSA-4420121|Reactome:R-HSA-202245|Reactome:R-HSA-8849068|Reactome:R-HSA-9006332|Reactome:R-HSA-2038387|Reactome:R-HSA-1839065|Reactome:R-HSA-354073|Reactome:R-HSA-389354|Reactome:R-HSA-191636|Reactome:R-HSA-2033485|Reactome:R-HSA-1250315|Reactome:R-HSA-2424484|Reactome:R-HSA-3928583|Reactome:R-HSA-9665709|Reactome:R-HSA-171011|Reactome:R-HSA-8874082|Reactome:R-HSA-1295609|Reactome:R-HSA-2029989|Reactome:R-HSA-2730882|Reactome:R-HSA-8853313|Reactome:R-HSA-5655270|Reactome:R-HSA-2033488|Reactome:R-HSA-1472121|Reactome:R-HSA-4420117|Reactome:R-HSA-5624486|Reactome:R-HSA-1524186|Reactome:R-HSA-9026502|Reactome:R-HSA-9698005|Reactome:R-HSA-1963582|Reactome:R-HSA-8875451|Reactome:R-HSA-8848124|Reactome:R-HSA-445091|Reactome:R-HSA-419646|Reactome:R-HSA-190408|Reactome:R-HSA-8848758|Reactome:R-HSA-9664275|Reactome:R-HSA-983703|Reactome:R-HSA-5637795|Reactome:R-HSA-8851933|Reactome:R-HSA-5655278|Reactome:R-HSA-8849042|Reactome:R-HSA-9034814|Reactome:R-HSA-5218851|Reactome:R-HSA-391866|Reactome:R-HSA-2029449|Reactome:R-HSA-9024726|Reactome:R-HSA-9673761|Reactome:R-HSA-9664278|Reactome:R-HSA-8857583|Reactome:R-HSA-5218828|Reactome:R-HSA-9698003|Reactome:R-HSA-2671850|Reactome:R-HSA-9026510|Reactome:R-HSA-5686587|Reactome:R-HSA-5655341|Reactome:R-HSA-2023455|Reactome:R-HSA-202168|Reactome:R-HSA-2038944|Reactome:R-HSA-5654607|Reactome:R-HSA-2395801|Reactome:R-HSA-909726|Reactome:R-HSA-9032854|Reactome:R-HSA-982807|Reactome:R-HSA-399947|Reactome:R-HSA-5654575|Reactome:R-HSA-879925|Reactome:R-HSA-9664976|Reactome:R-HSA-445084|Reactome:R-HSA-9634390|Reactome:R-HSA-9703437|Reactome:R-HSA-9672173|Reactome:R-HSA-9606159|Reactome:R-HSA-3928580|EC:2.7.10.2|Reactome:R-HSA-5654578|Reactome:R-HSA-9665032|Reactome:R-HSA-9027273|Reactome:R-HSA-182969|Reactome:R-HSA-6784319|Reactome:R-HSA-205289|Reactome:R-HSA-2396594|Reactome:R-HSA-9012650|Reactome:R-HSA-9034875|Reactome:R-HSA-2671742|Reactome:R-HSA-909718|Reactome:R-HSA-374701|Reactome:R-HSA-5654605|Reactome:R-HSA-5655243|Reactome:R-HSA-2033486|Reactome:R-HSA-190427|Reactome:R-HSA-2730862|Reactome:R-HSA-8867041|Reactome:R-HSA-170991|Reactome:R-HSA-2671829|Reactome:R-HSA-9665411|Reactome:R-HSA-191062|Reactome:R-HSA-2730833|Reactome:R-HSA-9673756|Reactome:R-HSA-5621355|Reactome:R-HSA-9703438|Reactome:R-HSA-5621363|Reactome:R-HSA-9664588|Reactome:R-HSA-2586553|Reactome:R-HSA-5654149|Reactome:R-HSA-9665389|Reactome:R-HSA-114600|Reactome:R-HSA-210291|Reactome:R-HSA-8983872|Reactome:R-HSA-8848873|Reactome:R-HSA-1225960|Reactome:R-HSA-1251922|Reactome:R-HSA-873922|Reactome:R-HSA-1225952|Reactome:R-HSA-8848818|Reactome:R-HSA-202233|Reactome:R-HSA-432129|Reactome:R-HSA-2029453|Reactome:R-HSA-452100|Reactome:R-HSA-8848005|Reactome:R-HSA-5654428|Reactome:R-HSA-5637796|Reactome:R-HSA-8855237|Reactome:R-HSA-8942607|Reactome:R-HSA-174164|Reactome:R-HSA-2012082|Reactome:R-HSA-2424487|Reactome:R-HSA-3215391|Reactome:R-HSA-2454239|Reactome:R-HSA-9033284|Reactome:R-HSA-202165|Reactome:R-HSA-2428926|Reactome:R-HSA-6790087|Reactome:R-HSA-4420128|Reactome:R-HSA-2424486|Reactome:R-HSA-8857577|Reactome:R-HSA-3928578|Reactome:R-HSA-9026890|Reactome:R-HSA-5683930|Reactome:R-HSA-8964252|Reactome:R-HSA-9026579|Reactome:R-HSA-8849032|Reactome:R-HSA-418872|Reactome:R-HSA-373747|Reactome:R-HSA-373750|Reactome:R-HSA-388831|Reactome:R-HSA-873919|Reactome:R-HSA-5218806|Reactome:R-HSA-5218640|Reactome:R-HSA-451942|Reactome:R-HSA-2201322|Reactome:R-HSA-5654582|Reactome:R-HSA-1248655|Reactome:R-HSA-912629|Reactome:R-HSA-452097|Reactome:R-HSA-9034714|Reactome:R-HSA-6806974|Reactome:R-HSA-1888198|Reactome:R-HSA-9032426|Reactome:R-HSA-8848975|Reactome:R-HSA-2033490|Reactome:R-HSA-202307|Reactome:R-HSA-429441|Reactome:R-HSA-8848776|Reactome:R-HSA-2012087|Reactome:R-HSA-9664261|Reactome:R-HSA-9666425|Reactome:R-HSA-6784006|Reactome:R-HSA-9027425|Reactome:R-HSA-391865|Reactome:R-HSA-879909|Reactome:R-HSA-8857925|Reactome:R-HSA-9670412|Reactome:R-HSA-186786|Reactome:R-HSA-1168394|Reactome:R-HSA-9612085|Reactome:R-HSA-9606163|Reactome:R-HSA-5218830|Reactome:R-HSA-9672175|Reactome:R-HSA-389086|Reactome:R-HSA-429449|Reactome:R-HSA-1839098|Reactome:R-HSA-1169421|Reactome:R-HSA-1839112|Reactome:R-HSA-190413|Reactome:R-HSA-210872|Reactome:R-HSA-5218812|Reactome:R-HSA-9699578|Reactome:R-HSA-2029984|Reactome:R-HSA-170070|Reactome:R-HSA-3928648|Reactome:R-HSA-3928610|Reactome:R-HSA-4093332|Reactome:R-HSA-9011241|Reactome:R-HSA-9669890|Reactome:R-HSA-5654655|Reactome:R-HSA-2404193|Reactome:R-HSA-2730851|Reactome:R-HSA-434836|Reactome:R-HSA-5654408|Reactome:R-HSA-1295540|Reactome:R-HSA-5654634|Reactome:R-HSA-443817|Reactome:R-HSA-873924|Reactome:R-HSA-1433506|Reactome:R-HSA-5655284|Reactome:R-HSA-1963586|Reactome:R-HSA-5654407|Reactome:R-HSA-8848726|Reactome:R-HSA-983709|Reactome:R-HSA-2730843|Reactome:R-HSA-5654418|Reactome:R-HSA-5654397|Reactome:R-HSA-8875817|Reactome:R-HSA-445085|Reactome:R-HSA-9669911|Reactome:R-HSA-4420206|Reactome:R-HSA-9665704|Reactome:R-HSA-873918|Reactome:R-HSA-5607750|Reactome:R-HSA-2730886|Reactome:R-HSA-1671691|Reactome:R-HSA-8853309|Reactome:R-HSA-909729|Reactome:R-HSA-9612996|Reactome:R-HSA-8849102|Reactome:R-HSA-9027272|Reactome:R-HSA-9606162|Reactome:R-HSA-2404199|Reactome:R-HSA-1250348|Reactome:R-HSA-1982066|Reactome:R-HSA-1307963|Reactome:R-HSA-2730884|Reactome:R-HSA-2730888|Reactome:R-HSA-190326|Reactome:R-HSA-5654628|Reactome:R-HSA-508282|Reactome:R-HSA-9670418|Reactome:R-HSA-2730858|Reactome:R-HSA-9018572|Reactome:R-HSA-8848077|Reactome:R-HSA-354124|Reactome:R-HSA-399946|Reactome:R-HSA-391871|Reactome:R-HSA-391156|Reactome:R-HSA-1839067|Reactome:R-HSA-9706350|Reactome:R-HSA-5654653|Reactome:R-HSA-9603420|Reactome:R-HSA-1247844|Reactome:R-HSA-8849463|Reactome:R-HSA-9028728|Reactome:R-HSA-377640|Reactome:R-HSA-2197698|Reactome:R-HSA-428888|Reactome:R-HSA-5218820|Reactome:R-HSA-5607745|Reactome:R-HSA-5654147|Reactome:R-HSA-380780|Reactome:R-HSA-2454208|Reactome:R-HSA-8876948|Reactome:R-HSA-9680248|Reactome:R-HSA-5621370|Reactome:R-HSA-3928604|Reactome:R-HSA-8937807|Reactome:R-HSA-5690702|Reactome:R-HSA-177934|Reactome:R-HSA-2395412|Reactome:R-HSA-2023460|Reactome:R-HSA-8937844|Reactome:R-HSA-5654222|Reactome:R-HSA-2029268|Reactome:R-HSA-1433542|Reactome:R-HSA-202291|Reactome:R-HSA-112333|Reactome:R-HSA-68954|Reactome:R-HSA-177930|Reactome:R-HSA-8848606|Reactome:R-HSA-3928594|Reactome:R-HSA-8964242|Reactome:R-HSA-69195|Reactome:R-HSA-9029155|Reactome:R-HSA-9026464|Reactome:R-HSA-8876230|Reactome:R-HSA-9695834|Reactome:R-HSA-8956659|Reactome:R-HSA-177937|Reactome:R-HSA-418859|Reactome:R-HSA-202248|Reactome:R-HSA-5654587		molecular_function											owl:Class	
CHEBI:18059	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009347	biolink:NamedThing	aspartate carbamoyltransferase complex	A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides.	got7fsn_ti					Note that in eukaryotes, aspartate carbamoyltransferase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term.									cellular_component											owl:Class	
GO:0048443	biolink:NamedThing	stamen development	The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure.	got7fsn_ti											GO:0048425			biological_process											owl:Class	
GO:0016572	biolink:NamedThing	histone phosphorylation	The modification of histones by addition of phosphate groups.	got7fsn_ti														biological_process											owl:Class	
GO:0016191	biolink:NamedThing	synaptic vesicle uncoating	The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane.	got7fsn_ti	synaptic vesicle coat depolymerization|synaptic vesicle coat protein depolymerization													biological_process											owl:Class	
GO:0048488	biolink:NamedThing	synaptic vesicle endocytosis	A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.	got7fsn_ti	synaptic vesicle retrieval	https://github.com/geneontology/synapse/issues/230									GO:0008099			biological_process											owl:Class	
GO:0005854	biolink:NamedThing	nascent polypeptide-associated complex	A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.	got7fsn_ti	NAC|NACA													cellular_component											owl:Class	
GO:0043314	biolink:NamedThing	negative regulation of neutrophil degranulation	Any process that stops, prevents, or reduces the rate of neutrophil degranulation.	got7fsn_ti	inhibition of neutrophil degranulation|down regulation of neutrophil degranulation|down-regulation of neutrophil degranulation|downregulation of neutrophil degranulation|negative regulation of neutrophil granule exocytosis													biological_process											owl:Class	
GO:0003189	biolink:NamedThing	aortic valve formation	The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti							dph	2009-10-08T01:05:44Z						biological_process											owl:Class	
GO:0003180	biolink:NamedThing	aortic valve morphogenesis	The process in which the structure of the aortic valve is generated and organized.	got7fsn_ti							dph	2009-10-08T11:29:42Z						biological_process											owl:Class	
GO:0099174	biolink:NamedThing	regulation of presynapse organization	Any process that modulates the physical form of a presynapse.	got7fsn_ti	regulation of presynapse organisation|regulation of presynapse organization and biogenesis|regulation of presynapse structure													biological_process											owl:Class	
GO:1990015	biolink:NamedThing	ensheathing process	A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma.	got7fsn_ti	ensheathing process of Schwann cell						pr	2012-12-19T09:42:15Z				NIF_Subcellular:sao1376748732		cellular_component											owl:Class	
GO:0007419	biolink:NamedThing	ventral cord development	The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.	got7fsn_ti														biological_process											owl:Class	
GO:0015423	biolink:NamedThing	ABC-type maltose transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in).	got7fsn_ti	ABC-type maltose transporter|ATP-dependent maltose transmembrane transporter activity|maltose-transporting ATPase activity|ATPase-coupled maltose transmembrane transporter activity|maltose ABC transporter|maltooligosaccharide-importing ATPase activity											EC:7.5.2.1|RHEA:22132|MetaCyc:3.6.3.19-RXN		molecular_function											owl:Class	
GO:1904981	biolink:NamedThing	maltose transmembrane transport	The process in which maltose is transported across a membrane.	got7fsn_ti							vw	2016-02-28T21:14:04Z						biological_process											owl:Class	
GO:0097094	biolink:NamedThing	craniofacial suture morphogenesis	The process in which any suture between cranial and/or facial bones is generated and organized.	got7fsn_ti							pr	2011-07-05T02:51:54Z						biological_process											owl:Class	
GO:1990013	biolink:NamedThing	presynaptic grid	A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane.	got7fsn_ti	pre-synaptic grid						pr	2012-12-13T09:00:35Z				NIF_Subcellular:sao1730664005		cellular_component											owl:Class	
GO:0048786	biolink:NamedThing	presynaptic active zone	A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.	got7fsn_ti	presynaptic specialization|pre-synaptic active zone component|pre-synaptic active zone											NIF_Subcellular:sao792027222		cellular_component											owl:Class	
GO:0010152	biolink:NamedThing	pollen maturation	The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains.	got7fsn_ti														biological_process											owl:Class	
GO:1904173	biolink:NamedThing	regulation of histone demethylase activity (H3-K4 specific)	Any process that modulates the frequency, rate or extent of histone demethylase activity (H3-K4 specific).	got7fsn_ti							dph	2015-04-24T19:29:32Z						biological_process											owl:Class	
GO:0030916	biolink:NamedThing	otic vesicle formation	The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.	got7fsn_ti	otocyst biosynthesis|otocyst formation													biological_process											owl:Class	
GO:0030080	biolink:NamedThing	B875 antenna complex	Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm.	got7fsn_ti	LH1 complex|light harvesting complex I													cellular_component											owl:Class	
GO:0030078	biolink:NamedThing	light-harvesting complex, core complex	Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria.	got7fsn_ti														cellular_component											owl:Class	
GO:0090540	biolink:NamedThing	bacterial cellulose biosynthetic process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria.	got7fsn_ti	bacterial cellulose biosynthesis						tb	2013-02-11T16:32:44Z						biological_process											owl:Class	
GO:0120260	biolink:NamedThing	ciliary microtubule quartet	A set of four specialized microtubules that originates from the basal bodies and wraps around the ciliary pocket membrane, likely supporting its distinct flask shape.	got7fsn_ti	ciliary MtQ	https://github.com/geneontology/go-ontology/issues/20035			Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.		krc	2020-09-29T16:22:22Z						cellular_component											owl:Class	
GO:0035905	biolink:NamedThing	ascending aorta development	The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.	got7fsn_ti							bf	2011-06-24T11:02:01Z						biological_process											owl:Class	
GO:0004917	biolink:NamedThing	interleukin-7 receptor activity	Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-7R|IL-7 receptor activity													molecular_function											owl:Class	
GO:0038111	biolink:NamedThing	interleukin-7-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-7-mediated signalling pathway|IL-7-mediated signaling pathway						bf	2012-03-22T10:19:27Z						biological_process											owl:Class	
GO:0071910	biolink:NamedThing	determination of liver left/right asymmetry	Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.	got7fsn_ti							mah	2010-09-22T10:26:47Z						biological_process											owl:Class	
GO:0120102	biolink:NamedThing	bacterial-type flagellum secretion apparatus	A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament.	got7fsn_ti	bacterial-type flagellum export apparatus						krc	2017-10-03T16:13:24Z						cellular_component											owl:Class	
GO:0009425	biolink:NamedThing	bacterial-type flagellum basal body	One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor.	got7fsn_ti	flagellin-based flagellum basal body|flagellar basal body													cellular_component											owl:Class	
GO:0042175	biolink:NamedThing	nuclear outer membrane-endoplasmic reticulum membrane network	The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.	got7fsn_ti	nuclear envelope-endoplasmic reticulum network|nuclear envelope-ER network|NE-ER continuum|nuclear membrane-ER network|nuclear envelope-endoplasmic reticulum continuum|nuclear membrane-endoplasmic reticulum continuum|NE-ER network													cellular_component											owl:Class	
GO:0004169	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase activity	Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.	got7fsn_ti	dolichol phosphomannose-protein mannosyltransferase activity|dolichyl-phosphate-mannose-protein O-mannosyltransferase activity|dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase activity|protein O-mannosyltransferase activity|protein O-D-mannosyltransferase activity|O-glycoside mannosyltransferase				Note that this activity has never been observed in green plants. However, N- and C-mannosylation may occur in these species; see figure 1 in PMID:21558543.							Reactome:R-HSA-5615604|EC:2.4.1.109|Reactome:R-HSA-5615556|Reactome:R-HSA-5615637|MetaCyc:2.4.1.109-RXN		molecular_function											owl:Class	
GO:0035269	biolink:NamedThing	protein O-linked mannosylation	The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.	got7fsn_ti	protein amino acid O-linked mannosylation													biological_process											owl:Class	
GO:0080136	biolink:NamedThing	priming of cellular response to stress	The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress.	got7fsn_ti	priming of stress response|priming of response to stress						dhl	2009-05-06T05:05:15Z						biological_process											owl:Class	
GO:0034099	biolink:NamedThing	luminal surveillance complex	A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:1903962	biolink:NamedThing	arachidonate transmembrane transporter activity	Enables the transfer of arachidonate from one side of a membrane to the other.	got7fsn_ti	arachidonic acid transporter activity|arachidonate transporter activity				An example of this is S100A9 in human (P06702) in PMID:15642721 (inferred from direct assay).		bhm	2015-02-25T15:51:12Z						molecular_function											owl:Class	
GO:0031453	biolink:NamedThing	positive regulation of heterochromatin assembly	Any process that activates or increases the frequency, rate or extent of heterochromatin formation.	got7fsn_ti	stimulation of heterochromatin formation|upregulation of heterochromatin formation|up regulation of heterochromatin formation|activation of heterochromatin formation|positive regulation of heterochromatin formation|up-regulation of heterochromatin formation													biological_process											owl:Class	
GO:0051884	biolink:NamedThing	regulation of timing of anagen	Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.	got7fsn_ti	regulation of anagen													biological_process											owl:Class	
GO:0090689	biolink:NamedThing	cleavage furrow leading edge	The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring.	got7fsn_ti							tb	2016-07-26T16:00:10Z						cellular_component											owl:Class	
GO:0032154	biolink:NamedThing	cleavage furrow	The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.	got7fsn_ti					While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists.							Wikipedia:Cleavage_furrow		cellular_component											owl:Class	
GO:0021997	biolink:NamedThing	neural plate axis specification	The pattern specification process in which the axes of the nervous system are established.	got7fsn_ti	neural plate axis determination													biological_process											owl:Class	
GO:0060896	biolink:NamedThing	neural plate pattern specification	The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.	got7fsn_ti							dph	2009-08-13T02:06:27Z						biological_process											owl:Class	
GO:1902673	biolink:NamedThing	left posteriolateral basal body	Any ciliary basal body that is part of a left posteriolateral flagellum found in Giardia species (trophozoite stage).	got7fsn_ti	ciliary basal body of left posteriolateral flagellum|cilium basal body of left posteriolateral flagellum|microtubule basal body of left posteriolateral cilium|ciliary basal body of left posterolateral cilium|cilium basal body of left posteriolateral cilium|microtubule basal body of left posterolateral cilium|microtubule basal body of left posterolateral flagellum|cilium basal body of left posterolateral cilium|cilial basal body of left posteriolateral cilium|cilial basal body of left posteriolateral flagellum|microtubule basal body of left posteriolateral flagellum|ciliary basal body of left posteriolateral cilium|cilial basal body of left posterolateral cilium|ciliary basal body of left posterolateral flagellum|left posteriolateral flagellum ciliary basal body|cilium basal body of left posterolateral flagellum|cilial basal body of left posterolateral flagellum				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:49:25Z						cellular_component											owl:Class	
GO:1990677	biolink:NamedThing	mitochondrial inner membrane assembly complex	A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion.	got7fsn_ti	mitochondrion inner membrane assembly complex|inner membrane assembly complex|INAC complex				An example of this is INA22 in Saccharomyces cerevisiae (P40576) in PMID:24942160 (inferred from direct assay/mutant phenotype/etc.).		bhm	2015-03-02T13:14:52Z						cellular_component											owl:Class	
GO:0014036	biolink:NamedThing	neural crest cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0031673	biolink:NamedThing	H zone	A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.	got7fsn_ti	H band|H disc											Wikipedia:Sarcomere#bands		cellular_component											owl:Class	
GO:0007566	biolink:NamedThing	embryo implantation	Attachment of the blastocyst to the uterine lining.	got7fsn_ti	blastocyst implantation													biological_process											owl:Class	
GO:0015648	biolink:NamedThing	lipid-linked peptidoglycan transporter activity	Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.	got7fsn_ti	lipid-linked murein transporter activity													molecular_function											owl:Class	
GO:0015836	biolink:NamedThing	lipid-linked peptidoglycan transport	The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	lipid-linked murein transport													biological_process											owl:Class	
GO:0090651	biolink:NamedThing	apical cytoplasm	The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells.	got7fsn_ti							tb	2015-07-01T15:46:19Z						cellular_component											owl:Class	
GO:0045177	biolink:NamedThing	apical part of cell	The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.	got7fsn_ti	apical region of cell													cellular_component											owl:Class	
GO:1904048	biolink:NamedThing	regulation of spontaneous neurotransmitter secretion	Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion.	got7fsn_ti	regulation of stimulus-independent neurotransmitter secretion				An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).		pad	2015-03-17T10:37:11Z						biological_process											owl:Class	
GO:0098814	biolink:NamedThing	spontaneous synaptic transmission	The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.	got7fsn_ti	basal synaptic transmission				This is typically measured via detection of mini excitatory post-synaptic currents (mEPSCs).									biological_process											owl:Class	
GO:0001711	biolink:NamedThing	endodermal cell fate commitment	The cell differentiation process that results in commitment of a cell to become part of the endoderm.	got7fsn_ti	endoderm cell fate commitment													biological_process											owl:Class	
GO:0035987	biolink:NamedThing	endodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.	got7fsn_ti	endoderm cell differentiation						bf	2011-08-25T04:50:36Z						biological_process											owl:Class	
GO:1901261	biolink:NamedThing	regulation of sorocarp spore cell differentiation	Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation.	got7fsn_ti							jl	2012-08-15T09:44:30Z						biological_process											owl:Class	
GO:0038143	biolink:NamedThing	ERBB3:ERBB2 complex	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3.	got7fsn_ti	NRG1/2:ERBB3:ERBB2|EGFR:ERBB2 heterodimer						bf	2012-03-30T02:16:56Z						cellular_component											owl:Class	
GO:0071123	biolink:NamedThing	alpha9-beta1 integrin-VEGF-C complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.	got7fsn_ti	ITGA9-ITGB1-VEGFC complex						mah	2009-11-13T02:22:27Z						cellular_component											owl:Class	
GO:0061606	biolink:NamedThing	N-terminal protein amino acid propionylation	The propionylation of the N-terminal amino acid of proteins.	got7fsn_ti							dph	2014-02-11T14:13:05Z						biological_process											owl:Class	
GO:0045626	biolink:NamedThing	negative regulation of T-helper 1 cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.	got7fsn_ti	down-regulation of T-helper 1 cell differentiation|down regulation of T-helper 1 cell differentiation|downregulation of T-helper 1 cell differentiation|negative regulation of T-helper 1 cell development|inhibition of T-helper 1 cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0042088	biolink:NamedThing	T-helper 1 type immune response	An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.	got7fsn_ti	Th1 immune response													biological_process											owl:Class	
GO:0048195	biolink:NamedThing	Golgi membrane priming complex assembly	The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex.	got7fsn_ti	formation of dictyosome membrane priming complex|formation of Golgi membrane priming complex													biological_process											owl:Class	
GO:0060491	biolink:NamedThing	regulation of cell projection assembly	Any process that modulates the rate, frequency, or extent of cell projection assembly.	got7fsn_ti	regulation of cell projection formation													biological_process											owl:Class	
GO:0097457	biolink:NamedThing	hippocampal mossy fiber	Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.	got7fsn_ti							pr	2012-12-19T16:51:57Z				NIF_Subcellular:nlx_subcell_100312		cellular_component											owl:Class	
CL:0001033	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032179	biolink:NamedThing	germ tube	The slender tubular outgrowth first produced by most spores in germination.	got7fsn_ti												Wikipedia:Germ_tube		cellular_component											owl:Class	
GO:0070790	biolink:NamedThing	phialide development	The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips.	got7fsn_ti	development of secondary sterigmata						mah	2009-07-08T02:32:30Z						biological_process											owl:Class	
GO:0070787	biolink:NamedThing	conidiophore development	The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.	got7fsn_ti							mah	2009-07-08T01:30:36Z						biological_process											owl:Class	
GO:0036478	biolink:NamedThing	L-dopa decarboxylase activator activity	Interacts with and increases L-dopa decarboxylase activity.	got7fsn_ti	DDC activator activity				GO:0036478 is reserved for cases when the activator directly interacts with L-dopa decarboxylase. When activation of L-dopa decarboxylase activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'positive regulation of L-dopa decarboxylase activity ; GO:1903200'.		bf	2014-07-24T10:10:51Z						molecular_function											owl:Class	
GO:0036468	biolink:NamedThing	L-dopa decarboxylase activity	Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine.	got7fsn_ti	DDC activity|4-dihydroxyl-L-phenylalanine decarboxylase activity|DOPA decarboxylase activity						bf	2014-07-21T09:22:24Z				RHEA:12272		molecular_function											owl:Class	
GO:0019209	biolink:NamedThing	kinase activator activity	Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0033674	biolink:NamedThing	positive regulation of kinase activity	Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	got7fsn_ti	stimulation of kinase activity|upregulation of kinase activity|up regulation of kinase activity|up-regulation of kinase activity|kinase activator													biological_process											owl:Class	
GO:0004534	biolink:NamedThing	5'-3' exoribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.	got7fsn_ti												Reactome:R-HSA-429845|EC:3.1.13.-		molecular_function											owl:Class	
GO:0150006	biolink:NamedThing	urease activator complex	A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function.	got7fsn_ti														cellular_component											owl:Class	
GO:0043419	biolink:NamedThing	urea catabolic process	The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.	got7fsn_ti	urea decomposition|urea breakdown|urea degradation|urea catabolism													biological_process											owl:Class	
GO:0060533	biolink:NamedThing	bronchus cartilage morphogenesis	The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.	got7fsn_ti							dph	2009-04-10T08:47:41Z						biological_process											owl:Class	
GO:0060434	biolink:NamedThing	bronchus morphogenesis	The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.	got7fsn_ti														biological_process											owl:Class	
GO:0009783	biolink:NamedThing	photosystem II antenna complex	The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).	got7fsn_ti														cellular_component											owl:Class	
GO:0072354	biolink:NamedThing	histone kinase activity (H3-T3 specific)	Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3.	got7fsn_ti	histone-threonine kinase activity (H3-T3 specific)|histone threonine kinase activity (H3-T3 specific)						mah	2010-11-12T04:27:57Z						molecular_function											owl:Class	
GO:0072355	biolink:NamedThing	histone H3-T3 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 3 of the histone.	got7fsn_ti							mah	2010-11-12T04:28:56Z						biological_process											owl:Class	
GO:0061032	biolink:NamedThing	visceral serous pericardium development	The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.	got7fsn_ti	epicardium development						dph	2010-02-09T09:52:49Z						biological_process											owl:Class	
GO:0060039	biolink:NamedThing	pericardium development	The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.	got7fsn_ti														biological_process											owl:Class	
GO:0045292	biolink:NamedThing	mRNA cis splicing, via spliceosome	The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.	got7fsn_ti	nuclear mRNA cis splicing, via U2-type spliceosome|nuclear mRNA cis splicing, via spliceosome|splicing													biological_process											owl:Class	
CHEBI:16947	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0039705	biolink:NamedThing	viral translational readthrough	The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.	got7fsn_ti	viral stop codon readthrough|viral RNA suppression of termination				This term is intended to annotate gene products involved in the process of viral translational readthrough, not viral proteins produced by this translation process.		bf	2013-11-25T13:20:37Z				VZ:859		biological_process											owl:Class	
GO:0003968	biolink:NamedThing	RNA-directed 5'-3' RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.	got7fsn_ti	ribonucleic acid replicase activity|phage f2 replicase|Q-beta replicase activity|RNA-dependent RNA polymerase activity|RNA-dependent ribonucleate nucleotidyltransferase activity|RDRP|transcriptase|nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|RNA replicase activity|polymerase L|ribonucleic acid-dependent ribonucleic acid polymerase activity|RNA-directed RNA polymerase activity|ribonucleic synthetase activity|PB2 proteins|ribonucleic replicase activity|PB1 proteins|RNA nucleotidyltransferase (RNA-directed) activity|RNA-dependent RNA replicase activity|RNA synthetase activity|3D polymerase activity											Reactome:R-HSA-9681674|Reactome:R-HSA-9681651|Reactome:R-HSA-192916|EC:2.7.7.48|Reactome:R-HSA-168301|MetaCyc:RNA-DIRECTED-RNA-POLYMERASE-RXN|Reactome:R-HSA-9694277|Reactome:R-HSA-9694605|Reactome:R-HSA-192851|Reactome:R-HSA-9685681|Reactome:R-HSA-9694581|Reactome:R-HSA-9682465|Reactome:R-HSA-9694344|Reactome:R-HSA-192624|Reactome:R-HSA-9682563|Reactome:R-HSA-9681840|Reactome:R-HSA-9694549|Reactome:R-HSA-168280|Reactome:R-HSA-192832|Reactome:R-HSA-9694506|Reactome:R-HSA-9694792|Reactome:R-HSA-9685639		molecular_function											owl:Class	
GO:0001172	biolink:NamedThing	transcription, RNA-templated	The cellular synthesis of RNA on a template of RNA.	got7fsn_ti	transcription, RNA-dependent						krc	2011-03-14T03:54:46Z						biological_process											owl:Class	
GO:1990018	biolink:NamedThing	tail portion of tanycyte	Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell.	got7fsn_ti	tail portion						pr	2012-12-19T15:21:20Z				NIF_Subcellular:sao1749953771		cellular_component											owl:Class	
GO:0045694	biolink:NamedThing	regulation of embryo sac egg cell differentiation	Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation.	got7fsn_ti	regulation of female gametophyte egg cell differentiation													biological_process											owl:Class	
GO:0038058	biolink:NamedThing	TNFSF11 receptor activity	Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function.	got7fsn_ti	tumor necrosis factor ligand superfamily member 11 receptor activity|RANKL receptor activity						bf	2012-01-04T03:31:54Z						molecular_function											owl:Class	
GO:0005507	biolink:NamedThing	copper ion binding	Binding to a copper (Cu) ion.	got7fsn_ti	copper/cadmium binding|copper binding													molecular_function											owl:Class	
GO:0045152	biolink:NamedThing	antisigma factor binding	Binding to an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.	got7fsn_ti	antisigma factor antagonist activity													molecular_function											owl:Class	
GO:0099583	biolink:NamedThing	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol.	got7fsn_ti	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels													molecular_function											owl:Class	
GO:0016060	biolink:NamedThing	metarhodopsin inactivation	The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it.	got7fsn_ti														biological_process											owl:Class	
GO:0021900	biolink:NamedThing	ventricular zone cell fate commitment	The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0030992	biolink:NamedThing	intraciliary transport particle B	The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.	got7fsn_ti	intraflagellar transport particle B|IFT complex B|IFT B complex|intraflagellar transport complex B				Note that we deem cilia and microtubule-based flagella to be equivalent.									cellular_component											owl:Class	
GO:0001740	biolink:NamedThing	Barr body	A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.	got7fsn_ti												Wikipedia:Barr_body|NIF_Subcellular:sao1571698684		cellular_component											owl:Class	
GO:0106232	biolink:NamedThing	hydroxyisourate hydrolase complex	A hydrolase complex that converts 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline. This is the second step of the three-step enzymatic reaction that degrades uric acid to (S)-allantoin.	got7fsn_ti	HIUH complex|5-hydroxyisourate hydrolase complex|HIU hydrolase complex						hjd	2019-10-31T16:34:19Z						cellular_component											owl:Class	
GO:0033971	biolink:NamedThing	hydroxyisourate hydrolase activity	Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+).	got7fsn_ti	5-hydroxyisourate hydrolase activity|HIUHase activity|5-hydroxyisourate amidohydrolase activity											KEGG_REACTION:R06601|MetaCyc:3.5.2.17-RXN|RHEA:23736|EC:3.5.2.17		molecular_function											owl:Class	
GO:0072117	biolink:NamedThing	head kidney formation	The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.	got7fsn_ti							mah	2010-02-22T11:17:20Z						biological_process											owl:Class	
GO:1904385	biolink:NamedThing	cellular response to angiotensin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.	got7fsn_ti							sl	2015-06-23T17:27:14Z						biological_process											owl:Class	
GO:0097059	biolink:NamedThing	CNTFR-CLCF1 complex	A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). The complex is secreted into the extracellular space.	got7fsn_ti	sCNTFR-CLC complex						pr	2011-05-26T10:43:22Z						cellular_component											owl:Class	
GO:0033104	biolink:NamedThing	type VI protein secretion system complex	A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence.	got7fsn_ti	T6SS complex													cellular_component											owl:Class	
GO:0055109	biolink:NamedThing	invagination involved in gastrulation with mouth forming second	The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0044385	biolink:NamedThing	integral to membrane of host cell	Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane. Occurring in a host cell.	got7fsn_ti							jl	2011-12-13T04:08:03Z						cellular_component											owl:Class	
GO:0061358	biolink:NamedThing	negative regulation of Wnt protein secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.	got7fsn_ti							dph	2010-10-08T01:15:15Z						biological_process											owl:Class	
GO:0006267	biolink:NamedThing	pre-replicative complex assembly involved in nuclear cell cycle DNA replication	The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation.	got7fsn_ti	pre-replicative complex formation|pre-RC complex assembly|pre-replicative complex assembly|nuclear pre-replicative complex assembly													biological_process											owl:Class	
GO:0000329	biolink:NamedThing	fungal-type vacuole membrane	The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.	got7fsn_ti	membrane of vacuole with cell cycle-correlated morphology|fungal-type vacuolar membrane													cellular_component											owl:Class	
GO:0003037	biolink:NamedThing	detection of pH by carotid body chemoreceptor signaling	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.	got7fsn_ti	detection of pH by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0048056	biolink:NamedThing	R3/R4 cell differentiation	The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0004103	biolink:NamedThing	choline kinase activity	Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+).	got7fsn_ti	choline phosphokinase activity|choline-ethanolamine kinase activity|choline kinase (phosphorylating)|ATP:choline phosphotransferase activity											MetaCyc:CHOLINE-KINASE-RXN|KEGG_REACTION:R01021|EC:2.7.1.32|Reactome:R-HSA-1483004|RHEA:12837		molecular_function											owl:Class	
GO:0006657	biolink:NamedThing	CDP-choline pathway	The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine.	got7fsn_ti	phosphatidylcholine biosynthesis from choline|Kennedy pathway											MetaCyc:PWY3O-450		biological_process											owl:Class	
GO:0060433	biolink:NamedThing	bronchus development	The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.	got7fsn_ti														biological_process											owl:Class	
GO:0052704	biolink:NamedThing	ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide	The pathway resulting in the formation of ergothioneine from histidine via a set of steps in which gamma-glutamyl-hercynylcysteine sulfoxide is formed as an intermediate.	got7fsn_ti	ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine	https://github.com/geneontology/go-ontology/issues/11163						2011-08-05T11:31:52Z				Wikipedia:Ergothioneine		biological_process											owl:Class	
GO:0043155	biolink:NamedThing	negative regulation of photosynthesis, light reaction	Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.	got7fsn_ti	down regulation of photosynthesis, light reaction|downregulation of photosynthesis, light reaction|inhibition of photosynthesis, light reaction|down-regulation of photosynthesis, light reaction													biological_process											owl:Class	
GO:0021587	biolink:NamedThing	cerebellum morphogenesis	The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	got7fsn_ti														biological_process											owl:Class	
GO:1903599	biolink:NamedThing	positive regulation of autophagy of mitochondrion	Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy.	got7fsn_ti	up-regulation of mitophagy|up regulation of mitophagy|upregulation of mitophagy|activation of mitochondrion degradation|upregulation of mitochondrion degradation|up regulation of mitochondrion degradation|activation of mitophagy|up-regulation of mitochondrion degradation|positive regulation of mitochondrial degradation				An example of this AMBRA1 - human (Q9C0C7) in PMID:21753002 inferred from direct assay		pad	2014-11-10T14:25:53Z						biological_process											owl:Class	
GO:0071077	biolink:NamedThing	adenosine 3',5'-bisphosphate transmembrane transporter activity	Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other.	got7fsn_ti	adenosine 3',5'-diphosphate transporter activity|adenosine 3'-phosphate-5'-phosphate transmembrane transporter activity						mah	2009-11-06T03:44:14Z						molecular_function											owl:Class	
GO:0071106	biolink:NamedThing	adenosine 3',5'-bisphosphate transmembrane transport	The process in which adenosine 3',5'-bisphosphate is transported across a membrane.	got7fsn_ti	adenosine 3',5'-bisphosphate membrane transport|adenosine 3',5'-diphosphate transport|adenosine 3'-phosphate-5'-phosphate transmembrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-11-12T10:40:49Z						biological_process											owl:Class	
GO:0010091	biolink:NamedThing	trichome branching	Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti											GO:0048274			biological_process											owl:Class	
GO:0001706	biolink:NamedThing	endoderm formation	The formation of the endoderm during gastrulation.	got7fsn_ti	endoblast formation													biological_process											owl:Class	
GO:0045453	biolink:NamedThing	bone resorption	The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.	got7fsn_ti												Wikipedia:Bone_resorption		biological_process											owl:Class	
GO:0002022	biolink:NamedThing	detection of dietary excess	The neurological process in which the brain senses excessive caloric intake.	got7fsn_ti														biological_process											owl:Class	
GO:0002021	biolink:NamedThing	response to dietary excess	The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.	got7fsn_ti														biological_process											owl:Class	
GO:0034777	biolink:NamedThing	recycling endosome lumen	The volume enclosed by the membranes of a recycling endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0021571	biolink:NamedThing	rhombomere 5 development	The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0070687	biolink:NamedThing	macropinocytic cup cytoskeleton	The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup.	got7fsn_ti	crown cytoskeleton						mah	2009-06-03T10:59:50Z						cellular_component											owl:Class	
GO:0002807	biolink:NamedThing	positive regulation of antimicrobial peptide biosynthetic process	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.	got7fsn_ti	stimulation of antimicrobial peptide biosynthetic process|up regulation of antimicrobial peptide biosynthetic process|activation of antimicrobial peptide biosynthetic process|upregulation of antimicrobial peptide biosynthetic process|up-regulation of antimicrobial peptide biosynthetic process													biological_process											owl:Class	
GO:0070521	biolink:NamedThing	alpha4-beta1 integrin-CD82 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.	got7fsn_ti														cellular_component											owl:Class	
GO:0051864	biolink:NamedThing	histone H3-methyl-lysine-36 demethylase activity	Catalysis of the removal of a methyl group from a modified lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone H3K36 demethylase activity|histone-lysine demethylase activity (H3-K36 specific)|[histone-H3]-lysine-36 demethylase activity|histone H3-lysine-36 demethylase activity|histone-lysine(H3-K36) demethylase activity|histone demethylase activity (H3-K36 specific)|histone-lysine (H3-K36) demethylase activity	https://github.com/geneontology/go-ontology/issues/21089												molecular_function											owl:Class	
GO:0070544	biolink:NamedThing	histone H3-K36 demethylation	The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.	got7fsn_ti	H3K36 demethylation													biological_process											owl:Class	
GO:0045191	biolink:NamedThing	regulation of isotype switching	Any process that modulates the frequency, rate or extent of isotype switching.	got7fsn_ti	regulation of class switch recombination|regulation of isotype switch recombination|regulation of class switching													biological_process											owl:Class	
GO:0002377	biolink:NamedThing	immunoglobulin production	The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	antibody production|immunoglobulin biosynthetic process|immunoglobulin secretion				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0048305|GO:0002378			biological_process											owl:Class	
GO:0032508	biolink:NamedThing	DNA duplex unwinding	The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.	got7fsn_ti	DNA unwinding|duplex DNA melting				Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.									biological_process											owl:Class	
GO:0097107	biolink:NamedThing	postsynaptic density assembly	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.	got7fsn_ti	post-synaptic density assembly|post synaptic density assembly|PSD assembly						pr	2011-07-27T05:21:39Z						biological_process											owl:Class	
GO:1904861	biolink:NamedThing	excitatory synapse assembly	The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.	got7fsn_ti	excitatory synapse formation						bf	2015-12-17T10:31:26Z						biological_process											owl:Class	
GO:0001755	biolink:NamedThing	neural crest cell migration	The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0002432	biolink:NamedThing	granuloma formation	The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.	got7fsn_ti														biological_process											owl:Class	
GO:0002544	biolink:NamedThing	chronic inflammatory response	Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.	got7fsn_ti														biological_process											owl:Class	
GO:0045035	biolink:NamedThing	sensory organ precursor cell division	The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron).	got7fsn_ti	sense organ precursor cell division													biological_process											owl:Class	
GO:0019069	biolink:NamedThing	viral capsid assembly	The assembly of a virus capsid from its protein subunits.	got7fsn_ti														biological_process											owl:Class	
GO:0071664	biolink:NamedThing	catenin-TCF7L2 complex	A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.	got7fsn_ti	catenin-TCF4 complex						mah	2010-02-12T03:19:16Z						cellular_component											owl:Class	
GO:0098711	biolink:NamedThing	iron ion import across plasma membrane	The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	ferrous ion import into cell|ferrous iron import into cell|ferrous iron import across plasma membrane|iron ion import into cell|iron import into cell						pr	2012-12-20T08:29:00Z			GO:0097460|GO:0098707|GO:0097459			biological_process											owl:Class	
GO:0006164	biolink:NamedThing	purine nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine nucleotide biosynthesis|purine nucleotide anabolism|purine nucleotide formation|purine nucleotide synthesis											MetaCyc:DENOVOPURINE2-PWY		biological_process											owl:Class	
GO:0022885	biolink:NamedThing	bacteriocin transmembrane transporter activity	Enables the transfer of a bacteriocin from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0043213	biolink:NamedThing	bacteriocin transport	The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.	got7fsn_ti														biological_process											owl:Class	
GO:0071691	biolink:NamedThing	cardiac muscle thin filament assembly	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle.	got7fsn_ti							mah	2010-02-25T03:57:01Z						biological_process											owl:Class	
GO:1990706	biolink:NamedThing	MAD1 complex	A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C).	got7fsn_ti	MAD1 homodimer						bhm	2015-03-17T15:49:16Z						cellular_component											owl:Class	
GO:0007424	biolink:NamedThing	open tracheal system development	The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.	got7fsn_ti					See also the fly_anatomy.ontology term 'tracheal system ; FBbt:00005024'.									biological_process											owl:Class	
GO:0031207	biolink:NamedThing	Sec62/Sec63 complex	A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.	got7fsn_ti	ER protein translocation subcomplex|Sec62/63 complex													cellular_component											owl:Class	
GO:0090624	biolink:NamedThing	endoribonuclease activity, cleaving miRNA-paired mRNA	Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.	got7fsn_ti							tb	2015-01-21T16:28:52Z						molecular_function											owl:Class	
GO:0035279	biolink:NamedThing	mRNA cleavage involved in gene silencing by miRNA	The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.	got7fsn_ti	gene silencing by miRNA, mRNA cleavage|miRNA-mediated gene silencing, mRNA cleavage|mRNA cleavage involved in gene silencing by microRNA													biological_process											owl:Class	
GO:0004159	biolink:NamedThing	dihydropyrimidine dehydrogenase (NAD+) activity	Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.	got7fsn_ti	5,6-dihydrouracil:NAD+ oxidoreductase activity|uracil reductase activity|dihydrothymine dehydrogenase (NAD+) activity|pyrimidine reductase activity|thymine reductase activity|dihydrouracil dehydrogenase (NAD+) activity	https://github.com/geneontology/go-ontology/issues/21891										EC:1.3.1.1|MetaCyc:DIHYDROURACIL-DEHYDROGENASE-NAD+-RXN|RHEA:20189|RHEA:28791		molecular_function											owl:Class	
GO:0000811	biolink:NamedThing	GINS complex	A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks.	got7fsn_ti	Go, Ichi, Ni and San complex													cellular_component											owl:Class	
GO:0020032	biolink:NamedThing	basal ring of apical complex	An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite.	got7fsn_ti	lower polar ring of apical complex|posterior polar ring of apical complex|preconoidal ring of apical complex													cellular_component											owl:Class	
GO:0009321	biolink:NamedThing	alkyl hydroperoxide reductase complex	An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides.	got7fsn_ti					See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'.									cellular_component											owl:Class	
GO:0021668	biolink:NamedThing	rhombomere 6 structural organization	The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti	rhombomere 6 structural organisation													biological_process											owl:Class	
GO:0038198	biolink:NamedThing	auxin receptor activity	Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone).	got7fsn_ti							bf	2013-12-05T15:47:42Z						molecular_function											owl:Class	
GO:0010011	biolink:NamedThing	auxin binding	Binding to auxin, a plant hormone that regulates aspects of plant growth.	got7fsn_ti	auxin receptor													molecular_function											owl:Class	
GO:0003383	biolink:NamedThing	apical constriction	The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.	got7fsn_ti							dph	2009-12-09T07:30:34Z						biological_process											owl:Class	
GO:0003040	biolink:NamedThing	excitation of vasomotor center by aortic body chemoreceptor signaling	The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.	got7fsn_ti	excitation of vasomotor center by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0048055	biolink:NamedThing	R2/R5 development	The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0051477	biolink:NamedThing	mannosylglycerate transmembrane transporter activity	Enables the transfer of a mannosylglycerate from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0051476	biolink:NamedThing	mannosylglycerate transport	The directed movement of mannosylglycerate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0005630	biolink:NamedThing	dityrosine layer of spore wall	The outermost layer of the spore wall, as described in Saccharomyces.	got7fsn_ti														cellular_component											owl:Class	
GO:2000521	biolink:NamedThing	negative regulation of immunological synapse formation	Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation.	got7fsn_ti	negative regulation of formation of immunological synapse						ebc	2011-03-23T10:18:19Z						biological_process											owl:Class	
GO:1990913	biolink:NamedThing	sperm head plasma membrane	The plasma membrane that is part of the head section of a sperm cell.	got7fsn_ti							sl	2015-12-07T23:14:04Z						cellular_component											owl:Class	
GO:0097524	biolink:NamedThing	sperm plasma membrane	A plasma membrane that is part of a sperm cell.	got7fsn_ti							pr	2013-10-18T11:31:17Z						cellular_component											owl:Class	
GO:1905787	biolink:NamedThing	regulation of detection of mechanical stimulus involved in sensory perception of touch	Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.	got7fsn_ti	regulation of perception of touch, sensory transduction of mechanical stimulus|regulation of perception of touch, sensory detection of mechanical stimulus|regulation of tactition, sensory detection of mechanical stimulus|regulation of perception of touch, detection of mechanical stimulus|regulation of sensory detection of mechanical stimulus during perception of touch|regulation of sensory transduction of mechanical stimulus during perception of touch						hbye	2017-01-09T15:11:04Z						biological_process											owl:Class	
GO:0035792	biolink:NamedThing	host cell postsynaptic membrane	A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.	got7fsn_ti	other organism post-synaptic membrane|other organism postsynaptic membrane						bf	2011-04-08T01:21:20Z						cellular_component											owl:Class	
GO:0072042	biolink:NamedThing	regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis	Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron.	got7fsn_ti							mah	2010-01-25T03:11:26Z						biological_process											owl:Class	
GO:0072090	biolink:NamedThing	mesenchymal stem cell proliferation involved in nephron morphogenesis	The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.	got7fsn_ti							mah	2010-02-08T02:05:54Z						biological_process											owl:Class	
GO:0005520	biolink:NamedThing	insulin-like growth factor binding	Binding to an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.	got7fsn_ti	IGF binding													molecular_function											owl:Class	
GO:0006415	biolink:NamedThing	translational termination	The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).	got7fsn_ti	translational complex disassembly|translation termination|protein synthesis termination										GO:0006443|GO:0006456			biological_process											owl:Class	
GO:0006401	biolink:NamedThing	RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.	got7fsn_ti	RNA catabolism|RNA degradation|RNA breakdown													biological_process											owl:Class	
GO:0032591	biolink:NamedThing	dendritic spine membrane	The portion of the plasma membrane surrounding a dendritic spine.	got7fsn_ti														cellular_component											owl:Class	
GO:0032590	biolink:NamedThing	dendrite membrane	The portion of the plasma membrane surrounding a dendrite.	got7fsn_ti														cellular_component											owl:Class	
GO:0061443	biolink:NamedThing	endocardial cushion cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.	got7fsn_ti							dph	2012-03-13T09:05:38Z						biological_process											owl:Class	
GO:0003197	biolink:NamedThing	endocardial cushion development	The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	got7fsn_ti							dph	2009-10-08T01:17:43Z						biological_process											owl:Class	
GO:0043656	biolink:NamedThing	host intracellular region	That space within the plasma membrane of a host cell.	got7fsn_ti	intracellular region of host|host intracellular													cellular_component											owl:Class	
GO:0003214	biolink:NamedThing	cardiac left ventricle morphogenesis	The process in which the left cardiac ventricle is generated and organized.	got7fsn_ti							dph	2009-10-13T09:50:08Z						biological_process											owl:Class	
GO:0070157	biolink:NamedThing	mitochondrial prolyl-tRNA aminoacylation	The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0097711	biolink:NamedThing	ciliary basal body-plasma membrane docking	The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.	got7fsn_ti	anchoring of the basal body to the plasma membrane|ciliary basal body docking				Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.		pr	2016-08-05T16:12:33Z				Reactome:R-HSA-5620912.1		biological_process											owl:Class	
GO:0030085	biolink:NamedThing	PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex	A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides.	got7fsn_ti														cellular_component											owl:Class	
GO:0070685	biolink:NamedThing	macropinocytic cup	A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.	got7fsn_ti	crown						mah	2009-06-03T10:18:00Z						cellular_component											owl:Class	
GO:0060892	biolink:NamedThing	limb basal epidermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti							dph	2009-08-13T01:41:47Z						biological_process											owl:Class	
GO:2000264	biolink:NamedThing	negative regulation of blood coagulation, extrinsic pathway	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway.	got7fsn_ti							mah	2010-11-23T11:44:42Z						biological_process											owl:Class	
GO:2000747	biolink:NamedThing	negative regulation of defecation rhythm	Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm.	got7fsn_ti	negative regulation of defecation cycle|negative regulation of defecation motor program|negative regulation of defecation behavior|negative regulation of DMP						bf	2011-06-15T03:23:10Z						biological_process											owl:Class	
GO:0030421	biolink:NamedThing	defecation	The expulsion of feces from the rectum.	got7fsn_ti												Wikipedia:Defecation		biological_process											owl:Class	
GO:1905798	biolink:NamedThing	positive regulation of intraciliary anterograde transport	Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport.	got7fsn_ti	up regulation of intraflagellar anterograde transport|activation of intraflagellar anterograde transport|positive regulation of intraflagellar anterograde transport|up-regulation of intraciliary anterograde transport|upregulation of intraflagellar anterograde transport|activation of intraciliary anterograde transport|up-regulation of intraflagellar anterograde transport|upregulation of intraciliary anterograde transport|up regulation of intraciliary anterograde transport						hbye	2017-01-11T12:56:01Z						biological_process											owl:Class	
GO:1903691	biolink:NamedThing	positive regulation of wound healing, spreading of epidermal cells	Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells.	got7fsn_ti	up-regulation of wound healing, spreading of epidermal cells|up regulation of wound healing, spreading of epidermal cells|upregulation of wound healing, spreading of epidermal cells|activation of wound healing, spreading of epidermal cells						als	2014-12-01T15:54:35Z						biological_process											owl:Class	
GO:0061200	biolink:NamedThing	clathrin-sculpted gamma-aminobutyric acid transport vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle.	got7fsn_ti	clathrin sculpted gamma-aminobutyric acid transport vesicle|clathrin sculpted GABA transport vesicle						dph	2010-07-29T10:40:43Z						cellular_component											owl:Class	
GO:0061003	biolink:NamedThing	positive regulation of dendritic spine morphogenesis	Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	got7fsn_ti							dph	2010-01-20T09:36:54Z						biological_process											owl:Class	
GO:0005669	biolink:NamedThing	transcription factor TFIID complex	A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.	got7fsn_ti														cellular_component											owl:Class	
GO:0035099	biolink:NamedThing	hemocyte migration	The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.	got7fsn_ti	arthropod blood cell migration|hemocyte cell migration													biological_process											owl:Class	
PATO:0015006	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097596	biolink:NamedThing	ventral disc supernumerary microtubule array	A partial left-handed spiral array of microtubules that lies generally dorsal to the main ventral disc microtubule array in Giardia species (trophozoite stage).	got7fsn_ti	ventral disk supernumerary microtubule array|supernumerary microtubule array				Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:25:07Z						cellular_component											owl:Class	
GO:0040007	biolink:NamedThing	growth	The increase in size or mass of an entire organism, a part of an organism or a cell.	got7fsn_ti	non-developmental growth|growth pattern				See also the biological process term 'cell growth ; GO:0016049'.						GO:0048590			biological_process											owl:Class	
GO:0070240	biolink:NamedThing	negative regulation of activated T cell autonomous cell death	Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.	got7fsn_ti	down regulation of activated T cell autonomous cell death|negative regulation of activated T cell apoptosis|negative regulation of activated T-lymphocyte autonomous cell death|negative regulation of activated cell autonomous cell death|downregulation of activated T cell autonomous cell death|negative regulation of ACAD|inhibition of activated T cell autonomous cell death|negative regulation of activated T-cell autonomous cell death|negative regulation of activated T lymphocyte autonomous cell death|down-regulation of activated T cell autonomous cell death													biological_process											owl:Class	
GO:0021542	biolink:NamedThing	dentate gyrus development	The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.	got7fsn_ti														biological_process											owl:Class	
GO:0021766	biolink:NamedThing	hippocampus development	The progression of the hippocampus over time from its initial formation until its mature state.	got7fsn_ti	hippocampal formation development													biological_process											owl:Class	
GO:0072221	biolink:NamedThing	metanephric distal convoluted tubule development	The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.	got7fsn_ti							mah	2010-03-18T03:35:27Z						biological_process											owl:Class	
GO:0072235	biolink:NamedThing	metanephric distal tubule development	The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule.	got7fsn_ti							mah	2010-03-18T03:45:37Z						biological_process											owl:Class	
GO:0010099	biolink:NamedThing	regulation of photomorphogenesis	Any process that modulates the rate or extent of photomorphogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:0038163	biolink:NamedThing	thrombopoietin-mediated signaling pathway	A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	THPO signaling pathway|thrombopoietin receptor signaling pathway|THPO/MPL signaling pathway						bf	2012-05-14T02:45:53Z						biological_process											owl:Class	
GO:0060928	biolink:NamedThing	atrioventricular node cell development	The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.	got7fsn_ti	AV node cell development						dph	2009-09-29T11:59:26Z						biological_process											owl:Class	
GO:0060922	biolink:NamedThing	atrioventricular node cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.	got7fsn_ti	AV node cell differentiation						dph	2009-09-29T11:07:06Z						biological_process											owl:Class	
GO:0061212	biolink:NamedThing	mesonephric juxtaglomerular apparatus development	The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.	got7fsn_ti							dph	2010-08-17T03:27:36Z						biological_process											owl:Class	
GO:0061908	biolink:NamedThing	phagophore	A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle.	got7fsn_ti	isolation membrane						dph	2017-06-29T16:59:19Z						cellular_component											owl:Class	
GO:0051913	biolink:NamedThing	regulation of synaptic plasticity by chemical substance	The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require.	got7fsn_ti	regulation of synaptic plasticity by drug													biological_process											owl:Class	
GO:1901629	biolink:NamedThing	regulation of presynaptic membrane organization	Any process that modulates the frequency, rate or extent of presynaptic membrane organization.	got7fsn_ti	regulation of presynaptic membrane organisation|regulation of pre-synaptic membrane organization						ans	2012-11-15T11:40:32Z						biological_process											owl:Class	
GO:0044852	biolink:NamedThing	nonrepetitive DNA condensation	The process in which chromatin structure of nonrepetitive regions of DNA is compacted prior to and during mitosis in eukaryotic cells.	got7fsn_ti	nonrepetitive DNA packaging						jl	2014-07-17T14:13:23Z						biological_process											owl:Class	
GO:0005899	biolink:NamedThing	insulin receptor complex	A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.	got7fsn_ti														cellular_component											owl:Class	
GO:0097413	biolink:NamedThing	Lewy body	Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.	got7fsn_ti	cytoplasmic inclusion						pr	2012-11-06T16:26:08Z				NIF_Subcellular:sao4933778419		cellular_component											owl:Class	
GO:0007454	biolink:NamedThing	labial disc morphogenesis	The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis.	got7fsn_ti	labial disc metamorphosis													biological_process											owl:Class	
GO:0035217	biolink:NamedThing	labial disc development	Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis.	got7fsn_ti														biological_process											owl:Class	
GO:0051460	biolink:NamedThing	negative regulation of corticotropin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.	got7fsn_ti	negative regulation of ACTH secretion|down regulation of adrenocorticotropin secretion|downregulation of adrenocorticotropin secretion|negative regulation of adrenotropic hormone secretion|negative regulation of adrenocorticotropic hormone secretion|negative regulation of adrenotropin secretion|down-regulation of adrenocorticotropin secretion|negative regulation of adrenocorticotropin secretion|negative regulation of corticotropic hormone secretion|inhibition of adrenocorticotropin secretion													biological_process											owl:Class	
GO:0030673	biolink:NamedThing	axolemma	The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.	got7fsn_ti	axonal membrane											NIF_Subcellular:sao250772229|Wikipedia:Axolemma		cellular_component											owl:Class	
GO:0080186	biolink:NamedThing	developmental vegetative growth	The increase in size or mass of non-reproductive plant parts.	got7fsn_ti							dhl	2011-08-17T03:45:53Z						biological_process											owl:Class	
GO:1904417	biolink:NamedThing	positive regulation of xenophagy	Any process that activates or increases the frequency, rate or extent of xenophagy.	got7fsn_ti	activation of xenophagy|up regulation of xenophagy|up-regulation of xenophagy|upregulation of xenophagy				An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype).		pad	2015-06-29T12:30:59Z						biological_process											owl:Class	
GO:0140332	biolink:NamedThing	lipopolysaccharide transfer activity	Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.	got7fsn_ti	intermembrane LPS transporter activity|intermembrane lipopolysaccharide transfer activity|lipopolysaccharide carrier activity|intermembrane lipopolysaccharide transporter activity						pg	2019-05-13T08:17:35Z						molecular_function											owl:Class	
GO:0015920	biolink:NamedThing	lipopolysaccharide transport	The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.	got7fsn_ti	LPS transport													biological_process											owl:Class	
GO:2000063	biolink:NamedThing	positive regulation of ureter smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.	got7fsn_ti							jl	2010-08-20T01:44:28Z						biological_process											owl:Class	
GO:0010307	biolink:NamedThing	acetylglutamate kinase regulator activity	Modulates the enzyme activity of acetylglutamate kinase.	got7fsn_ti														molecular_function											owl:Class	
GO:0044671	biolink:NamedThing	sorocarp spore cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).	got7fsn_ti							jl	2012-08-08T13:10:48Z						biological_process											owl:Class	
GO:0048837	biolink:NamedThing	sorocarp sorus development	The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure.  A sorocarp sorus is the spore containing structure of a sorocarp.	got7fsn_ti	sorocarp spore head formation|sorocarp spore head morphogenesis|sorocarp sorus formation													biological_process											owl:Class	
GO:0070142	biolink:NamedThing	synaptic vesicle budding	Evagination of a membrane to form a synaptic vesicle.	got7fsn_ti														biological_process											owl:Class	
GO:0048489	biolink:NamedThing	synaptic vesicle transport	The directed movement of synaptic vesicles.	got7fsn_ti	synaptic vesicle fusion|synaptic vesicle fission|synaptic vesicle trafficking										GO:0016181			biological_process											owl:Class	
GO:0048910	biolink:NamedThing	afferent axon development in anterior lateral line nerve	The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0048909	biolink:NamedThing	anterior lateral line nerve development	The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.	got7fsn_ti	ALLN development|rostral lateral line nerve development|nALL development										GO:0021734			biological_process											owl:Class	
GO:0070148	biolink:NamedThing	mitochondrial glutaminyl-tRNA aminoacylation	The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0005068	biolink:NamedThing	transmembrane receptor protein tyrosine kinase adaptor activity	The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way.	got7fsn_ti	transmembrane receptor protein tyrosine kinase adaptor protein activity|transmembrane receptor protein tyrosine kinase docking protein activity										GO:0005069			molecular_function											owl:Class	
GO:0007079	biolink:NamedThing	mitotic chromosome movement towards spindle pole	The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.	got7fsn_ti	mitotic chromosome movement|chromosome movement towards spindle pole during mitosis|chromosome migration to spindle pole during mitosis|sister chromosome movement towards spindle pole during mitosis|mitotic sister chromosome movement towards spindle pole|mitotic chromosome movement to spindle pole										GO:0007082			biological_process											owl:Class	
GO:0090626	biolink:NamedThing	plant epidermis morphogenesis	The process in which the anatomical structures of the plant epidermis are generated and organized.	got7fsn_ti							tb	2015-01-29T14:54:03Z						biological_process											owl:Class	
GO:0022624	biolink:NamedThing	proteasome accessory complex	A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0061407	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.	got7fsn_ti							dph	2012-01-12T11:39:10Z						biological_process											owl:Class	
GO:0070301	biolink:NamedThing	cellular response to hydrogen peroxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0015174	biolink:NamedThing	basic amino acid transmembrane transporter activity	Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3.	got7fsn_ti	basic amino acid permease activity|cationic amino acid transmembrane transporter activity|basic amino acid transporter activity										GO:0015326|GO:0005286	Reactome:R-HSA-8932851|Reactome:R-HSA-8959781		molecular_function											owl:Class	
GO:1990822	biolink:NamedThing	basic amino acid transmembrane transport	The directed movement of basic amino acids from one side of a membrane to the other.	got7fsn_ti							vw	2015-08-19T07:47:00Z						biological_process											owl:Class	
GO:0031321	biolink:NamedThing	ascospore-type prospore assembly	During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane.	got7fsn_ti	forespore formation|ascospore-type prospore formation													biological_process											owl:Class	
GO:0097650	biolink:NamedThing	B axonemal microtubule	An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet.	got7fsn_ti	B tubule						pr	2014-09-10T20:43:18Z						cellular_component											owl:Class	
GO:2000237	biolink:NamedThing	positive regulation of tRNA processing	Any process that activates or increases the frequency, rate or extent of tRNA processing.	got7fsn_ti	positive regulation of tRNA maturation						mah	2010-11-10T12:15:17Z						biological_process											owl:Class	
GO:0001657	biolink:NamedThing	ureteric bud development	The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0007520	biolink:NamedThing	myoblast fusion	A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
CL:0000056	biolink:NamedThing			got7fsn_ti																									owl:Class	
NCBITaxon:33083	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000463	biolink:NamedThing	positive regulation of excitatory postsynaptic potential	Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	got7fsn_ti	positive regulation of excitatory post-synaptic membrane potential|positive regulation of EPSP						rl	2011-03-04T02:43:32Z						biological_process											owl:Class	
GO:0035072	biolink:NamedThing	ecdysone-mediated induction of salivary gland cell autophagic cell death	Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis.	got7fsn_ti	ecdysone-mediated induction of programmed cell death of salivary gland cells by autophagy|ecdysone-mediated induction of salivary gland cell programmed cell death by autophagy|ecdysone-mediated induction of autophagic cell death of salivary gland cells													biological_process											owl:Class	
GO:0051123	biolink:NamedThing	RNA polymerase II preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.	got7fsn_ti	RNA polymerase II transcription PIC biosynthesis|RNA polymerase II transcriptional preinitiation complex formation|RNA polymerase II transcriptional preinitiation complex assembly|RNA polymerase II transcription PIC formation													biological_process											owl:Class	
GO:0006367	biolink:NamedThing	transcription initiation from RNA polymerase II promoter	Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.	got7fsn_ti	transcription initiation from Pol II promoter				Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.									biological_process											owl:Class	
GO:0003777	biolink:NamedThing	microtubule motor activity	A motor activity that generates movement along a microtubule, driven by ATP hydrolysis.	got7fsn_ti	kinesin motor activity|dynein ATPase activity|kinesin|dynein|kinetochore motor activity|axonemal motor activity|ATP-dependent microtubule motor activity	https://github.com/geneontology/go-ontology/issues/18664			Consider also annotating to the molecular function term 'microtubule binding ; GO:0008017'.		vw	2016-04-04T10:59:42Z			GO:1990939	Reactome:R-HSA-265160|Reactome:R-HSA-9610627|Reactome:R-HSA-177479		molecular_function											owl:Class	
GO:0001534	biolink:NamedThing	radial spoke	Protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules.	got7fsn_ti												Wikipedia:Radial_spoke		cellular_component											owl:Class	
GO:0002494	biolink:NamedThing	lipid antigen transport	The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0007403	biolink:NamedThing	glial cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti											GO:0043361			biological_process											owl:Class	
GO:1902868	biolink:NamedThing	positive regulation of retina development in camera-type eye	Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye.	got7fsn_ti	up regulation of retinal development|activation of retina development in camera-type eye|positive regulation of retinal development|upregulation of retina development in camera-style eye|up-regulation of retina development in camera-type eye|up-regulation of retinal development|activation of retinal development|activation of retina development in camera-style eye|positive regulation of retina development in camera-style eye|upregulation of retina development in camera-type eye|up-regulation of retina development in camera-style eye|up regulation of retina development in camera-style eye|upregulation of retinal development|up regulation of retina development in camera-type eye						mr	2014-04-03T15:24:29Z						biological_process											owl:Class	
GO:0002919	biolink:NamedThing	positive regulation of peripheral B cell anergy	Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.	got7fsn_ti	up-regulation of peripheral B cell anergy|upregulation of peripheral B cell anergy|activation of peripheral B cell anergy|up regulation of peripheral B cell anergy|stimulation of peripheral B cell anergy													biological_process											owl:Class	
GO:0036310	biolink:NamedThing	ATP-dependent DNA/DNA annealing activity	An ATP-dependent activity that facilitates the formation of a complementary double-stranded DNA molecule.	got7fsn_ti	ATP-dependent DNA annealing activity|annealing helicase activity|nucleoside-triphosphatase activity involved in DNA annealing|DNA rewinding activity	https://github.com/geneontology/go-ontology/issues/19669|https://github.com/geneontology/go-ontology/issues/9815|https://github.com/geneontology/go-ontology/issues/12465					bf	2012-08-14T15:24:29Z				Reactome:R-HSA-5686642		molecular_function											owl:Class	
GO:0042471	biolink:NamedThing	ear morphogenesis	The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.	got7fsn_ti	hearing organ morphogenesis													biological_process											owl:Class	
GO:0048701	biolink:NamedThing	embryonic cranial skeleton morphogenesis	The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.	got7fsn_ti	embryonic cranium morphogenesis													biological_process											owl:Class	
GO:0001841	biolink:NamedThing	neural tube formation	The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.	got7fsn_ti	neural tube morphogenesis|neurulation										GO:0001679	Wikipedia:Neurulation		biological_process											owl:Class	
GO:0021578	biolink:NamedThing	hindbrain maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.	got7fsn_ti														biological_process											owl:Class	
GO:0106165	biolink:NamedThing	negative regulation of exonucleolytic catabolism of deadenylated mRNA	Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.	got7fsn_ti							hjd	2019-01-15T15:42:13Z						biological_process											owl:Class	
GO:0000288	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.	got7fsn_ti	mRNA catabolic process, deadenylylation-dependent|mRNA degradation, deadenylation-dependent decay|mRNA catabolism, deadenylylation-dependent|deadenylation-dependent mRNA decay|mRNA catabolic process, deadenylation-dependent|nuclear mRNA catabolic process, deadenylation-dependent decay|mRNA catabolism, deadenylation-dependent|mRNA breakdown, deadenylation-dependent decay	https://github.com/geneontology/go-ontology/issues/20568												biological_process											owl:Class	
GO:0010235	biolink:NamedThing	guard mother cell cytokinesis	The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells.	got7fsn_ti	guard mother cell division													biological_process											owl:Class	
GO:0031430	biolink:NamedThing	M band	The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines.	got7fsn_ti	midline|mesophragma|M disc|M line											Wikipedia:Sarcomere#bands		cellular_component											owl:Class	
GO:0098009	biolink:NamedThing	viral terminase, large subunit	The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit.	got7fsn_ti	virus terminase, large subunit				This term should only be used when the large subunit consists of more than one polypeptide.		bm	2012-07-25T10:13:00Z						cellular_component											owl:Class	
GO:0019093	biolink:NamedThing	mitochondrial RNA localization	Any process in which mitochondrial RNA is transported to, or maintained in, a specific location.	got7fsn_ti	mtRNA localization|mitochondrial RNA localisation|establishment and maintenance of mitochondrial RNA localization													biological_process											owl:Class	
GO:0038057	biolink:NamedThing	TNFSF11 binding	Binding to tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family.	got7fsn_ti	RANKL binding|receptor activator of nuclear factor kappa-B ligand binding|TRANCE binding|tumor necrosis factor ligand superfamily member 11 binding|osteoprotegerin ligand binding|OPGL binding|osteoclast differentiation factor binding|tumor necrosis factor (ligand) superfamily member 11 binding|CD254 binding|tumor necrosis factor superfamily member 11 binding|ODF binding|TNF-related activation-induced cytokine binding						bf	2012-01-04T03:25:59Z						molecular_function											owl:Class	
GO:1990260	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter using a mechanism that involves the localization of a transcription factor and initiated in response to the DNA damage checkpoint signaling.	got7fsn_ti							al	2014-01-07T17:10:11Z						biological_process											owl:Class	
GO:0042699	biolink:NamedThing	follicle-stimulating hormone signaling pathway	The series of molecular signals mediated by follicle-stimulating hormone.	got7fsn_ti	follicle-stimulating hormone signalling pathway|follicle stimulating hormone signalling pathway|follicle stimulating hormone signaling pathway													biological_process											owl:Class	
GO:0001541	biolink:NamedThing	ovarian follicle development	The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.	got7fsn_ti	follicular phase													biological_process											owl:Class	
GO:0004918	biolink:NamedThing	interleukin-8 receptor activity	Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-8 receptor activity|IL-8R													molecular_function											owl:Class	
GO:0038112	biolink:NamedThing	interleukin-8-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-8-mediated signalling pathway|IL-8-mediated signaling pathway						bf	2012-03-22T10:19:59Z						biological_process											owl:Class	
GO:0097543	biolink:NamedThing	ciliary inversin compartment	Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium.	got7fsn_ti	flagellar inversin compartment|flagellum inversin compartment|Inv compartment of the cilium|cilial inversin compartment|cilium inversin compartment|inversin compartment				Note that cilia and eukaryotic flagella are deemed to be equivalent.		pr	2013-12-12T11:14:36Z						cellular_component											owl:Class	
GO:0060443	biolink:NamedThing	mammary gland morphogenesis	The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	got7fsn_ti														biological_process											owl:Class	
GO:2000827	biolink:NamedThing	mitochondrial RNA surveillance	The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.	got7fsn_ti	RNA surveillance in mitochondria|aberrant RNA catabolic process in mitochondrion|RNA quality control in mitochondria|RNA quality control in mitochondrion|aberrant RNA catabolic process in mitochondria						bf	2011-07-20T01:33:23Z						biological_process											owl:Class	
GO:1904818	biolink:NamedThing	visceral peritoneum development	The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.	got7fsn_ti							dph	2015-11-17T19:00:17Z						biological_process											owl:Class	
GO:1904820	biolink:NamedThing	peritoneum development	The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure.	got7fsn_ti	peritonaeum development						dph	2015-11-18T17:23:51Z						biological_process											owl:Class	
GO:0052324	biolink:NamedThing	plant-type cell wall cellulose biosynthetic process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.	got7fsn_ti	cell wall cellulose biosynthesis|cellulose biosynthesis during cell wall biosynthesis													biological_process											owl:Class	
GO:0072553	biolink:NamedThing	terminal button organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.	got7fsn_ti	terminal button organisation|synaptic bouton organization|bouton organization|presynaptic bouton organization|terminal bouton organization						mah	2011-01-25T04:09:35Z						biological_process											owl:Class	
GO:2000636	biolink:NamedThing	positive regulation of primary miRNA processing	Any process that activates or increases the frequency, rate or extent of primary microRNA processing.	got7fsn_ti	positive regulation of pri-miRNA processing|positive regulation of primary microRNA processing						dph	2011-04-18T03:50:56Z						biological_process											owl:Class	
GO:0008029	biolink:NamedThing	pentraxin receptor activity	Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	pentaxin receptor				Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP).									molecular_function											owl:Class	
GO:0001864	biolink:NamedThing	pentraxin binding	Binding to a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.	got7fsn_ti					Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP).									molecular_function											owl:Class	
GO:0015091	biolink:NamedThing	ferric iron transmembrane transporter activity	Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other.	got7fsn_ti					Ferric iron is rarely transported in the free form. Some bacteria have a system in which an outer membrane protein takes iron away from host ferritin or lactoferrin and transport it to a Fe3+ binding protein in the periplasm. The periplasmic protein then delivers the Fe3+ to a transport system located in the cytoplasmic membrane. Consider also GO:0015343 siderophore transmembrane transporter activity.									molecular_function											owl:Class	
GO:1904431	biolink:NamedThing	positive regulation of t-circle formation	Any process that activates or increases the frequency, rate or extent of t-circle formation.	got7fsn_ti	up-regulation of t-circle formation|positive regulation of telomeric circle formation|activation of t-circle formation|upregulation of t-circle formation|up regulation of telomeric circle formation|upregulation of telomeric circle formation|up-regulation of telomeric circle formation|up regulation of t-circle formation|activation of telomeric circle formation						nc	2015-07-03T15:15:58Z						biological_process											owl:Class	
GO:0072112	biolink:NamedThing	glomerular visceral epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.	got7fsn_ti	podocyte differentiation						mah	2010-02-22T10:52:11Z						biological_process											owl:Class	
GO:0048091	biolink:NamedThing	positive regulation of female pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females.	got7fsn_ti	upregulation of female pigmentation|stimulation of female pigmentation|up-regulation of female pigmentation|up regulation of female pigmentation|activation of female pigmentation													biological_process											owl:Class	
GO:2001257	biolink:NamedThing	regulation of cation channel activity	Any process that modulates the frequency, rate or extent of cation channel activity.	got7fsn_ti	regulation of nonselective cation channel activity|regulation of cation diffusion facilitator activity						vk	2011-12-07T07:14:43Z						biological_process											owl:Class	
GO:0098655	biolink:NamedThing	cation transmembrane transport	The process in which a cation is transported across a membrane.	got7fsn_ti	ATP hydrolysis coupled cation transmembrane transport										GO:0099132			biological_process											owl:Class	
GO:0150048	biolink:NamedThing	cerebellar granule cell to Purkinje cell synapse	A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum.	got7fsn_ti	cerebellar parallel fiber to Purkinje cell synapse						bc	2018-04-23T14:44:40Z						cellular_component											owl:Class	
CL:0000121	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060426	biolink:NamedThing	lung vasculature development	The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.	got7fsn_ti	pulmonary vasculature development													biological_process											owl:Class	
GO:0008493	biolink:NamedThing	tetracycline transmembrane transporter activity	Enables the transfer of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).	got7fsn_ti	tetracycline transporter activity|tetracyclin transporter activity													molecular_function											owl:Class	
GO:0015904	biolink:NamedThing	tetracycline transmembrane transport	The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).	got7fsn_ti	tetracycline transport|tetracyclin transport													biological_process											owl:Class	
GO:0003149	biolink:NamedThing	membranous septum morphogenesis	The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.	got7fsn_ti							tb	2009-09-22T07:51:41Z						biological_process											owl:Class	
GO:0060412	biolink:NamedThing	ventricular septum morphogenesis	The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.	got7fsn_ti	interventricular septum morphogenesis													biological_process											owl:Class	
GO:1903463	biolink:NamedThing	regulation of mitotic cell cycle DNA replication	Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication.	got7fsn_ti	regulation of DNA replication involved in S phase involved in mitotic cell cycle|regulation of mitotic nuclear cell cycle DNA replication|regulation of DNA replication involved in S-phase involved in mitotic cell cycle|regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|regulation of DNA replication during S phase involved in mitotic cell cycle						vw	2014-09-23T13:38:25Z						biological_process											owl:Class	
GO:0038089	biolink:NamedThing	positive regulation of cell migration by vascular endothelial growth factor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.	got7fsn_ti	VEGF-A-induced cell migration|positive regulation of cell migration by vascular endothelial growth factor signalling pathway|VEGF-induced cell migration|positive regulation of cell migration by VEGF signaling pathway						bf	2012-02-02T03:40:13Z						biological_process											owl:Class	
GO:0015187	biolink:NamedThing	glycine transmembrane transporter activity	Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.	got7fsn_ti	glycine betaine/proline porter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|glycine transporter activity													molecular_function											owl:Class	
GO:0015816	biolink:NamedThing	glycine transport	The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0070801	biolink:NamedThing	positive regulation of conidiophore stalk development	Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.	got7fsn_ti							mah	2009-07-08T04:11:22Z						biological_process											owl:Class	
GO:2001209	biolink:NamedThing	positive regulation of transcription elongation from RNA polymerase I promoter	Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.	got7fsn_ti	positive regulation of RNA elongation from Pol I promoter						se	2011-11-11T10:46:41Z						biological_process											owl:Class	
GO:0003036	biolink:NamedThing	detection of pH by aortic body chemoreceptor signaling	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body.	got7fsn_ti	detection of pH by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0042908	biolink:NamedThing	xenobiotic transport	The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	drug transport	https://github.com/geneontology/go-ontology/issues/19460									GO:0015893			biological_process											owl:Class	
GO:0070903	biolink:NamedThing	mitochondrial tRNA thio-modification	The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.	got7fsn_ti							mah	2009-09-02T04:11:17Z						biological_process											owl:Class	
GO:0021633	biolink:NamedThing	optic nerve structural organization	The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	got7fsn_ti	optic nerve structural organisation|CN II structural organization													biological_process											owl:Class	
GO:0150047	biolink:NamedThing	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential.	got7fsn_ti	G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential						bc	2018-04-23T10:51:20Z						molecular_function											owl:Class	
GO:0046696	biolink:NamedThing	lipopolysaccharide receptor complex	A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.	got7fsn_ti	LPS receptor complex				Note that this term should not be used to refer to CD14 alone, but the multiprotein receptor complex that it is part of.									cellular_component											owl:Class	
GO:1904959	biolink:NamedThing	regulation of cytochrome-c oxidase activity	Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.	got7fsn_ti	regulation of warburg's respiratory enzyme activity|regulation of complex IV (mitochondrial electron transport) activity|regulation of cytochrome c oxidase activity|regulation of cytochrome aa3 activity|regulation of indophenolase|regulation of ferrocytochrome c oxidase|regulation of indophenol oxidase|regulation of NADH cytochrome c oxidase|regulation of cytochrome oxidase activity|regulation of cytochrome a3 activity|regulation of ferrocytochrome-c:oxygen oxidoreductase|regulation of cbb3-type cytochrome c oxidase|regulation of caa3-type cytochrome c oxidase|regulation of aa3-type cytochrome c oxidase|regulation of ba3-type cytochrome c oxidase						tb	2016-02-09T22:18:27Z						biological_process											owl:Class	
GO:0045283	biolink:NamedThing	fumarate reductase complex	A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)).	got7fsn_ti					See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'.									cellular_component											owl:Class	
GO:0002520	biolink:NamedThing	immune system development	The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.	got7fsn_ti														biological_process											owl:Class	
GO:0003230	biolink:NamedThing	cardiac atrium development	The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.	got7fsn_ti							dph	2009-10-13T11:02:07Z						biological_process											owl:Class	
GO:1905142	biolink:NamedThing	positive regulation of apical ectodermal ridge formation	Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation.	got7fsn_ti	positive regulation of apical epidermal ridge formation|up-regulation of crista ectodermalis apicalis formation|upregulation of crista ectodermalis apicalis formation|up regulation of apical epidermal ridge formation|up regulation of apical ectodermal ridge formation|up-regulation of apical epidermal ridge formation|upregulation of AER formation|positive regulation of AER formation|up regulation of AER formation|activation of AER formation|upregulation of apical ectodermal ridge formation|upregulation of apical epidermal ridge formation|positive regulation of crista ectodermalis apicalis formation|up regulation of crista ectodermalis apicalis formation|up-regulation of apical ectodermal ridge formation|up-regulation of AER formation						dph	2016-04-13T12:16:57Z						biological_process											owl:Class	
GO:0001745	biolink:NamedThing	compound eye morphogenesis	The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.	got7fsn_ti	insect-type retina morphogenesis													biological_process											owl:Class	
GO:0030398	biolink:NamedThing	peroxisomal membrane disassembly	The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation.	got7fsn_ti	peroxisomal membrane catabolism|peroxisomal membrane breakdown|peroxisomal membrane degradation													biological_process											owl:Class	
GO:0030242	biolink:NamedThing	autophagy of peroxisome	The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.	got7fsn_ti	peroxisome degradation|pexophagy													biological_process											owl:Class	
GO:1990520	biolink:NamedThing	separase-securin complex	A protein complex that includes separase (a protease which cleaves cohesin as part of chromosome separation) and securin, a protease inhibitor. Chromosome separation is inhibited until securin is degraded by the Anaphase Promoting Complex (APC).	got7fsn_ti	Cut1-2 complex						vw	2014-10-23T10:34:52Z						cellular_component											owl:Class	
GO:0006930	biolink:NamedThing	substrate-dependent cell migration, cell extension	The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell.	got7fsn_ti	substrate-bound cell migration, cell extension													biological_process											owl:Class	
GO:0061252	biolink:NamedThing	mesonephric glomerular epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.	got7fsn_ti							dph	2010-08-30T01:23:50Z						biological_process											owl:Class	
GO:0034658	biolink:NamedThing	isopropylmalate transmembrane transporter activity	Enables the transfer of isopropylmalate from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0034659	biolink:NamedThing	isopropylmalate transport	The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1904839	biolink:NamedThing	negative regulation of male germ-line stem cell asymmetric division	Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division.	got7fsn_ti	inhibition of male germ-line stem cell asymmetric division|down regulation of male germ-line stem cell renewal|down regulation of male germ-line stem cell asymmetric division|down-regulation of male germ-line stem cell renewal|downregulation of male germ-line stem cell renewal|downregulation of male germ-line stem cell asymmetric division|inhibition of male germ-line stem cell renewal|negative regulation of male germ-line stem cell renewal|down-regulation of male germ-line stem cell asymmetric division						sl	2015-12-05T00:28:39Z						biological_process											owl:Class	
GO:1901041	biolink:NamedThing	positive regulation of peptide antigen transport	Any process that activates or increases the frequency, rate or extent of peptide antigen transport.	got7fsn_ti	up regulation of peptide antigen transport|activation of peptide antigen transport|upregulation of peptide antigen transport|up-regulation of peptide antigen transport						bf	2012-06-22T04:08:26Z						biological_process											owl:Class	
GO:0000916	biolink:NamedThing	actomyosin contractile ring contraction	The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.	got7fsn_ti	actomyosin contractile ring constriction|cytokinesis, actomyosin ring contraction|contractile ring contraction involved in cell cycle cytokinesis|cytokinesis, contractile ring contraction	https://github.com/geneontology/go-ontology/issues/21855												biological_process											owl:Class	
GO:0061988	biolink:NamedThing	karyosome formation	The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome.	got7fsn_ti							dph	2018-02-15T21:24:08Z						biological_process											owl:Class	
GO:1905791	biolink:NamedThing	negative regulation of mechanosensory behavior	Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior.	got7fsn_ti	down regulation of mechanosensory behaviour|negative regulation of behavioural response to mechanical stimulus|negative regulation of behavioral response to mechanical stimulus|down regulation of mechanosensory behavior|down regulation of behavioural response to mechanical stimulus|downregulation of mechanosensory behaviour|inhibition of behavioural response to mechanical stimulus|down regulation of behavioral response to mechanical stimulus|down-regulation of behavioural response to mechanical stimulus|inhibition of mechanosensory behaviour|negative regulation of mechanosensory behaviour|inhibition of behavioral response to mechanical stimulus|down-regulation of behavioral response to mechanical stimulus|inhibition of mechanosensory behavior|downregulation of behavioural response to mechanical stimulus|down-regulation of mechanosensory behaviour|downregulation of mechanosensory behavior|downregulation of behavioral response to mechanical stimulus|down-regulation of mechanosensory behavior						hbye	2017-01-09T15:17:15Z						biological_process											owl:Class	
GO:0050790	biolink:NamedThing	regulation of catalytic activity	Any process that modulates the activity of an enzyme.	got7fsn_ti	regulation of enzyme activity|regulation of metalloenzyme activity										GO:0048552			biological_process											owl:Class	
GO:0070520	biolink:NamedThing	alpha4-beta1 integrin-CD81 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.	got7fsn_ti	ITGA4-ITGB1-CD81 complex													cellular_component											owl:Class	
GO:0090399	biolink:NamedThing	replicative senescence	A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.	got7fsn_ti							tb	2011-01-05T02:32:29Z						biological_process											owl:Class	
GO:1903582	biolink:NamedThing	negative regulation of basophil degranulation	Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation.	got7fsn_ti	down regulation of basophil degranulation|downregulation of basophil degranulation|down-regulation of basophil degranulation|inhibition of basophil degranulation						sl	2014-10-31T17:37:33Z						biological_process											owl:Class	
GO:0043381	biolink:NamedThing	negative regulation of memory T cell differentiation	Any process that stops, prevents, or reduces the rate of memory T cell differentiation.	got7fsn_ti	down-regulation of memory T cell differentiation|negative regulation of memory T lymphocyte differentiation|down regulation of memory T cell differentiation|negative regulation of memory T-cell differentiation|downregulation of memory T cell differentiation|negative regulation of memory T cell development|inhibition of memory T cell differentiation|negative regulation of memory T-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0015855	biolink:NamedThing	pyrimidine nucleobase transport	The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	pyrimidine transmembrane transport|pyrimidine transport|pyrimidine base transport|pyrimidine base transmembrane transport													biological_process											owl:Class	
GO:0021994	biolink:NamedThing	progression of neural tube closure	The process in which the neural folds are fused extending from the initial closure points.	got7fsn_ti														biological_process											owl:Class	
GO:0023027	biolink:NamedThing	MHC class I protein binding, via antigen binding groove	Binding to a major histocompatibility complex class I molecules via the antigen binding groove.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0014838	biolink:NamedThing	myoblast fate specification involved in skeletal muscle regeneration	The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0014836	biolink:NamedThing	myoblast fate commitment involved in skeletal muscle regeneration	The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0032478	biolink:NamedThing	heterotetrameric decaprenyl diphosphate synthase complex	A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1.	got7fsn_ti														cellular_component											owl:Class	
GO:0051026	biolink:NamedThing	chiasma assembly	The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids.	got7fsn_ti														biological_process											owl:Class	
GO:0031568	biolink:NamedThing	mitotic G1 cell size control checkpoint signaling	A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of the cell cycle.	got7fsn_ti	signal transduction involved in mitotic cell cycle G1/S transition size control checkpoint|mitotic G1 cell size control checkpoint|G1 cell size control checkpoint|signal transduction involved in G1 cell size control checkpoint|G1 cell size control checkpoint signalling|mitotic cell cycle G1/S transition size control checkpoint										GO:0072450			biological_process											owl:Class	
GO:0000082	biolink:NamedThing	G1/S transition of mitotic cell cycle	The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.	got7fsn_ti														biological_process											owl:Class	
GO:0001554	biolink:NamedThing	luteolysis	The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.	got7fsn_ti												Wikipedia:Luteolysis		biological_process											owl:Class	
GO:0016494	biolink:NamedThing	C-X-C chemokine receptor activity	Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif.	got7fsn_ti														molecular_function											owl:Class	
GO:0031251	biolink:NamedThing	PAN complex	A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.	got7fsn_ti	poly(A) nuclease complex													cellular_component											owl:Class	
GO:0009426	biolink:NamedThing	bacterial-type flagellum basal body, distal rod	The portion of the central rod of the bacterial-type flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes.	got7fsn_ti	flagellin-based flagellum basal body, distal rod|flagellar basal body, distal rod													cellular_component											owl:Class	
GO:0097735	biolink:NamedThing	DIM/DIP cell wall layer	A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds.	got7fsn_ti							pr	2016-10-05T14:55:30Z						cellular_component											owl:Class	
GO:0048801	biolink:NamedThing	antennal joint morphogenesis	The process in which the anatomical structures of the antennal joint are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0070306	biolink:NamedThing	lens fiber cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.	got7fsn_ti	lens fibre cell differentiation													biological_process											owl:Class	
GO:0002088	biolink:NamedThing	lens development in camera-type eye	The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.	got7fsn_ti	lens development|lens development in camera-style eye													biological_process											owl:Class	
GO:0051200	biolink:NamedThing	positive regulation of prosthetic group metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.	got7fsn_ti	positive regulation of coenzyme and prosthetic group metabolic process|upregulation of prosthetic group metabolic process|positive regulation of prosthetic group metabolism|activation of prosthetic group metabolic process|up regulation of prosthetic group metabolic process|stimulation of prosthetic group metabolic process|positive regulation of coenzyme and prosthetic group metabolism|up-regulation of prosthetic group metabolic process													biological_process											owl:Class	
GO:0001070	biolink:NamedThing	RNA-binding transcription regulator activity	A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.	got7fsn_ti	RNA binding transcription factor activity|RNA binding transcription regulator activity	https://github.com/geneontology/go-ontology/issues/14872					krc	2010-10-21T04:19:17Z						molecular_function											owl:Class	
NCBITaxon:10239	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071059	biolink:NamedThing	alpha6-beta1 integrin-CD151 complex	A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.	got7fsn_ti	ITGA6-ITGB1-CD151 complex						mah	2009-11-03T04:01:23Z						cellular_component											owl:Class	
GO:0002001	biolink:NamedThing	renin secretion into blood stream	The regulated release of renin into the blood stream by juxtoglomerular cells.	got7fsn_ti	renin release into blood stream													biological_process											owl:Class	
GO:0120141	biolink:NamedThing	regulation of ecdysone receptor-mediated signaling pathway	Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway.	got7fsn_ti							krc	2018-03-22T17:10:29Z						biological_process											owl:Class	
GO:1903800	biolink:NamedThing	positive regulation of production of miRNAs involved in gene silencing by miRNA	Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.	got7fsn_ti	up regulation of microRNA metabolic process|up-regulation of gene silencing by miRNA, production of miRNAs|activation of production of microRNAs involved in gene silencing by microRNA|activation of microRNA-mediated gene silencing, production of microRNAs|upregulation of microRNA metabolism|up-regulation of microRNA metabolic process|activation of production of miRNAs involved in gene silencing by miRNA|positive regulation of microRNA-mediated gene silencing, production of microRNAs|positive regulation of production of microRNAs involved in gene silencing by microRNA|activation of microRNA metabolism|upregulation of production of microRNAs involved in gene silencing by microRNA|upregulation of miRNA biogenesis|up-regulation of microRNA biosynthetic process|positive regulation of microRNA biosynthetic process|positive regulation of microRNA biosynthesis|activation of gene silencing by miRNA, production of miRNAs|up-regulation of miRNA biogenesis|up regulation of gene silencing by miRNA, production of miRNAs|activation of microRNA biogenesis|upregulation of microRNA biosynthesis|up regulation of microRNA biosynthesis|upregulation of production of miRNAs involved in gene silencing by miRNA|activation of miRNA processing|activation of microRNA biosynthetic process|activation of microRNA metabolic process|positive regulation of miRNA-mediated gene silencing, production of miRNAs|upregulation of microRNA biosynthetic process|up-regulation of microRNA biosynthesis|positive regulation of microRNA metabolic process|up-regulation of microRNA-mediated gene silencing, production of microRNAs|up regulation of miRNA biogenesis|up regulation of microRNA biogenesis|up regulation of production of microRNAs involved in gene silencing by microRNA|upregulation of miRNA processing|upregulation of gene silencing by miRNA, production of miRNAs|upregulation of miRNA-mediated gene silencing, production of miRNAs|upregulation of microRNA biogenesis|positive regulation of miRNA processing|positive regulation of miRNA biogenesis|up-regulation of production of miRNAs involved in gene silencing by miRNA|up regulation of miRNA-mediated gene silencing, production of miRNAs|up-regulation of miRNA-mediated gene silencing, production of miRNAs|up-regulation of microRNA biogenesis|activation of microRNA biosynthesis|activation of miRNA biogenesis|activation of miRNA-mediated gene silencing, production of miRNAs|positive regulation of gene silencing by miRNA, production of miRNAs|up regulation of microRNA-mediated gene silencing, production of microRNAs|up regulation of microRNA metabolism|positive regulation of microRNA metabolism|up regulation of miRNA processing|up-regulation of production of microRNAs involved in gene silencing by microRNA|up-regulation of microRNA metabolism|up regulation of production of miRNAs involved in gene silencing by miRNA|positive regulation of microRNA biogenesis|up regulation of microRNA biosynthetic process|upregulation of microRNA-mediated gene silencing, production of microRNAs|upregulation of microRNA metabolic process|up-regulation of miRNA processing						rph	2015-01-15T13:58:31Z						biological_process											owl:Class	
GO:0140545	biolink:NamedThing	protein disaggregase activity	An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19173					pg	2020-11-10T16:57:19Z						molecular_function											owl:Class	
GO:1901584	biolink:NamedThing	tetrapeptide transmembrane transporter activity	Enables the transfer of tetrapeptide from one side of a membrane to the other.	got7fsn_ti							jl	2012-11-06T15:40:10Z						molecular_function											owl:Class	
GO:1901583	biolink:NamedThing	tetrapeptide transmembrane transport	The directed movement of tetrapeptide across a membrane.	got7fsn_ti	tetrapeptide membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		jl	2012-11-06T15:40:02Z						biological_process											owl:Class	
GO:0150077	biolink:NamedThing	regulation of neuroinflammatory response	Any process that modulates the frequency, rate or extent of neuroinflammatory response.	got7fsn_ti							bc	2018-07-26T12:32:18Z						biological_process											owl:Class	
GO:1901194	biolink:NamedThing	negative regulation of formation of translation preinitiation complex	Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex.	got7fsn_ti	inhibition of formation of translation preinitiation complex|down regulation of formation of translation pre-initiation complex|downregulation of formation of translation pre-initiation complex|down regulation of formation of translation preinitiation complex|down-regulation of translation preinitiation complex assembly|negative regulation of formation of translation pre-initiation complex|down regulation of translation preinitiation complex assembly|negative regulation of translation preinitiation complex assembly|inhibition of formation of translation pre-initiation complex|down-regulation of formation of translation pre-initiation complex|downregulation of formation of translation preinitiation complex|inhibition of translation preinitiation complex assembly|downregulation of translation preinitiation complex assembly|down-regulation of formation of translation preinitiation complex						ss	2012-07-25T02:31:41Z						biological_process											owl:Class	
GO:1901393	biolink:NamedThing	negative regulation of transforming growth factor beta1 activation	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation.	got7fsn_ti	down regulation of TGFB1 activation|inhibition of latent-TGF-beta1 activation|down-regulation of TGF-beta 1 activation|downregulation of latent-TGF-beta1 activation|down regulation of transforming growth factor-beta1 activation|downregulation of TGFB1 activation|negative regulation of TGFbeta 1 activation|down regulation of latent-TGF-beta1 activation|down-regulation of TGFB1 activation|inhibition of transforming growth factor-beta1 activation|downregulation of L-TGF-beta 1 activation|negative regulation of TGF-beta 1 activation|down-regulation of TGFbeta 1 activation|inhibition of L-TGF-beta 1 activation|down regulation of transforming growth factor beta1 activation|negative regulation of transforming growth factor-beta1 activation|down regulation of TGFbeta 1 activation|inhibition of transforming growth factor beta1 activation|down regulation of TGF-beta 1 activation|downregulation of TGFbeta 1 activation|inhibition of TGFB1 activation|down regulation of L-TGF-beta 1 activation|downregulation of transforming growth factor-beta1 activation|down-regulation of L-TGF-beta 1 activation|negative regulation of TGFB1 activation|negative regulation of L-TGF-beta 1 activation|inhibition of TGF-beta 1 activation|down-regulation of transforming growth factor beta1 activation|inhibition of TGFbeta 1 activation|negative regulation of latent-TGF-beta1 activation|down-regulation of transforming growth factor-beta1 activation|downregulation of transforming growth factor beta1 activation|down-regulation of latent-TGF-beta1 activation|downregulation of TGF-beta 1 activation						bf	2012-10-01T10:41:17Z						biological_process											owl:Class	
GO:0060888	biolink:NamedThing	limb epidermis stratification	The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis.	got7fsn_ti							dph	2009-08-13T12:45:48Z						biological_process											owl:Class	
GO:0035044	biolink:NamedThing	sperm aster formation	Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.	got7fsn_ti														biological_process											owl:Class	
GO:0097567	biolink:NamedThing	right tetrad	Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally).	got7fsn_ti					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:32:33Z						cellular_component											owl:Class	
GO:2001118	biolink:NamedThing	tetrahydromethanopterin biosynthetic process	The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.	got7fsn_ti	tetrahydromethanopterin biosynthesis						jl	2011-10-11T12:13:19Z						biological_process											owl:Class	
GO:0070527	biolink:NamedThing	platelet aggregation	The adhesion of one platelet to one or more other platelets via adhesion molecules.	got7fsn_ti	thrombocyte aggregation|blood platelet aggregation													biological_process											owl:Class	
GO:0032255	biolink:NamedThing	maintenance of secretory granule location	Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of secretory granule localization													biological_process											owl:Class	
GO:0032252	biolink:NamedThing	secretory granule localization	Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	secretory granule localisation|secretory granule clustering													biological_process											owl:Class	
GO:0021685	biolink:NamedThing	cerebellar granular layer structural organization	The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	got7fsn_ti	cerebellar granular layer structural organisation													biological_process											owl:Class	
GO:0021698	biolink:NamedThing	cerebellar cortex structural organization	The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	got7fsn_ti	cerebellar cortex structural organisation													biological_process											owl:Class	
GO:1990529	biolink:NamedThing	glycosylphosphatidylinositol-mannosyltransferase I complex	A protein complex that is involved in the transfer of the four mannoses in the GPI-anchor precursor. In yeast S. cerevisiae this complex consists of Pbn1p and Gpi14p and in rat this complex consists of PIG-X and PIG-M.	got7fsn_ti	GPI-MT-I complex						rb	2014-11-06T01:02:31Z						cellular_component											owl:Class	
GO:0009832	biolink:NamedThing	plant-type cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana.	got7fsn_ti	cell wall assembly|cell wall biosynthetic process|cell wall synthesis|cell wall anabolism|cell wall formation|cellulose and pectin-containing cell wall biogenesis													biological_process											owl:Class	
GO:0021560	biolink:NamedThing	abducens nerve development	The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	got7fsn_ti	cranial nerve VI development|cranial nerve 6 development|CN VI development													biological_process											owl:Class	
GO:0035813	biolink:NamedThing	regulation of renal sodium excretion	Any process that modulates the amount of sodium excreted in urine over a unit of time.	got7fsn_ti							bf	2011-04-20T01:26:30Z						biological_process											owl:Class	
OBO:OBA_0000001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070901	biolink:NamedThing	mitochondrial tRNA methylation	The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.	got7fsn_ti							mah	2009-09-02T04:08:00Z						biological_process											owl:Class	
GO:1905222	biolink:NamedThing	atrioventricular canal morphogenesis	The developmental process by which an atrioventricular canal is generated and organized.	got7fsn_ti	ependymal canal morphogenesis|AVC morphogenesis|atrial canal morphogenesis|canalis atrioventricularis morphogenesis|AV canal morphogenesis|atrio-ventricular canal morphogenesis						rl	2016-06-07T09:09:51Z						biological_process											owl:Class	
GO:0042897	biolink:NamedThing	polymyxin transmembrane transporter activity	Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other.	got7fsn_ti	polymyxin transporter activity													molecular_function											owl:Class	
GO:0042893	biolink:NamedThing	polymyxin transport	The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0032835	biolink:NamedThing	glomerulus development	The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.	got7fsn_ti	glomerular development													biological_process											owl:Class	
GO:1902429	biolink:NamedThing	positive regulation of water channel activity	Any process that activates or increases the frequency, rate or extent of water channel activity.	got7fsn_ti	up-regulation of water channel activity|upregulation of aquaporin|positive regulation of aquaporin|upregulation of water channel activity|activation of water channel activity|up-regulation of aquaporin|up regulation of water channel activity|aquaporin activation|activation of aquaporin|up regulation of aquaporin						bf	2013-09-23T12:56:49Z						biological_process											owl:Class	
GO:0007620	biolink:NamedThing	copulation	The act of sexual union between male and female, involving the transfer of sperm.	got7fsn_ti														biological_process											owl:Class	
GO:0040036	biolink:NamedThing	regulation of fibroblast growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.	got7fsn_ti	regulation of FGFR signaling pathway|regulation of FGF receptor signaling pathway|regulation of FGF receptor signalling pathway													biological_process											owl:Class	
GO:1903396	biolink:NamedThing	negative regulation of secondary cell septum biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis.	got7fsn_ti	down regulation of secondary cell septum biogenesis|inhibition of secondary cell septum biogenesis|downregulation of secondary cell septum biogenesis|down-regulation of secondary cell septum biogenesis						di	2014-08-29T21:42:26Z						biological_process											owl:Class	
GO:0032328	biolink:NamedThing	alanine transport	The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1904819	biolink:NamedThing	parietal peritoneum development	The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.	got7fsn_ti	peritoneal cavity lining development						dph	2015-11-17T19:00:24Z						biological_process											owl:Class	
GO:0070134	biolink:NamedThing	positive regulation of mitochondrial translational initiation	Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.	got7fsn_ti	positive regulation of mitochondrial translation initiation													biological_process											owl:Class	
GO:0072306	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.	got7fsn_ti	positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis						mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:0072309	biolink:NamedThing	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti							mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:0004363	biolink:NamedThing	glutathione synthase activity	Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate.	got7fsn_ti	gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)|glutathione synthetase activity|GSH synthetase activity											KEGG_REACTION:R00497|EC:6.3.2.3|Reactome:R-HSA-174394|Reactome:R-HSA-5602901|MetaCyc:GLUTATHIONE-SYN-RXN|RHEA:13557		molecular_function											owl:Class	
GO:0006750	biolink:NamedThing	glutathione biosynthetic process	The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.	got7fsn_ti	glutathione biosynthesis|glutathione formation|glutathione anabolism|glutathione synthesis											MetaCyc:GLUTATHIONESYN-PWY		biological_process											owl:Class	
GO:0014037	biolink:NamedThing	Schwann cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.	got7fsn_ti														biological_process											owl:Class	
GO:0002553	biolink:NamedThing	histamine secretion by mast cell	The regulated release of histamine by a mast cell or group of mast cells.	got7fsn_ti														biological_process											owl:Class	
GO:1903636	biolink:NamedThing	regulation of protein insertion into mitochondrial outer membrane	Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane.	got7fsn_ti	regulation of protein transport into mitochondrial outer membrane|regulation of protein import into mitochondrial outer membrane|regulation of mitochondrial outer membrane protein import						pga	2014-11-20T15:54:44Z						biological_process											owl:Class	
GO:0043225	biolink:NamedThing	ATPase-coupled inorganic anion transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in).	got7fsn_ti	anion ABC transporter|ATPase-coupled anion transmembrane transporter activity|anion-transporting ATPase activity|anion transmembrane-transporting ATPase activity|ATP-dependent anion transmembrane transporter activity											Reactome:R-HSA-1454916|Reactome:R-HSA-5690340		molecular_function											owl:Class	
GO:0098656	biolink:NamedThing	anion transmembrane transport	The process in which an anion is transported across a membrane.	got7fsn_ti	ATP hydrolysis coupled anion transmembrane transport										GO:0099133			biological_process											owl:Class	
GO:0071083	biolink:NamedThing	alphaV-beta3 integrin-CD47-FCER2 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).	got7fsn_ti	ITGAV-ITGB3-CD447-FCER2 complex						mah	2009-11-06T04:44:20Z						cellular_component											owl:Class	
GO:0043856	biolink:NamedThing	anti-sigma factor antagonist activity	The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity.	got7fsn_ti	anti-anti-sigma factor activity													molecular_function											owl:Class	
GO:0007556	biolink:NamedThing	regulation of juvenile hormone metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.	got7fsn_ti	regulation of juvenile hormone metabolism													biological_process											owl:Class	
GO:0006716	biolink:NamedThing	juvenile hormone metabolic process	The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	got7fsn_ti	juvenile hormone metabolism													biological_process											owl:Class	
GO:0043595	biolink:NamedThing	endospore cortex	A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan.	got7fsn_ti														cellular_component											owl:Class	
GO:0001897	biolink:NamedThing	cytolysis by symbiont of host cells	The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	pathogenesis|cytolysis by organism of host cells													biological_process											owl:Class	
GO:0061525	biolink:NamedThing	hindgut development	The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.	got7fsn_ti							dph	2013-06-14T11:22:21Z						biological_process											owl:Class	
GO:0099125	biolink:NamedThing	PAK family kinase-Sog2 complex	A protein kinase complex comprising a conserved PAK/GC/Ste20 family kinase, leucine rich repeat protein Sog2 family, which function as part of the cell shape network.	got7fsn_ti														cellular_component											owl:Class	
GO:0045314	biolink:NamedThing	regulation of compound eye photoreceptor development	Any process that modulates the frequency, rate or extent of compound eye photoreceptor development.	got7fsn_ti	regulation of eye photoreceptor development													biological_process											owl:Class	
GO:0046532	biolink:NamedThing	regulation of photoreceptor cell differentiation	Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	regulation of photoreceptor differentiation										GO:0045673			biological_process											owl:Class	
GO:0075026	biolink:NamedThing	regulation of appressorium initiation	Any process that modulates the frequency, rate or extent of symbiont appressorium initiation.	got7fsn_ti	regulation of appressorium initiation on or near host|regulation of initiation of appressorium on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0006393	biolink:NamedThing	termination of mitochondrial transcription	The process in which the synthesis of an RNA molecule using a mitochondrial DNA template is completed.	got7fsn_ti	mitochondrial transcription termination|RNA transcription termination from mitochondrial promoter													biological_process											owl:Class	
GO:0042881	biolink:NamedThing	D-galactonate transmembrane transporter activity	Enables the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042875	biolink:NamedThing	D-galactonate transmembrane transport	The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	D-galactonate transport													biological_process											owl:Class	
GO:0072265	biolink:NamedThing	metanephric capsule morphogenesis	The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	got7fsn_ti							mah	2010-03-30T02:54:49Z						biological_process											owl:Class	
GO:0060720	biolink:NamedThing	spongiotrophoblast cell proliferation	The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.	got7fsn_ti							dph	2009-06-11T09:50:35Z						biological_process											owl:Class	
GO:0090214	biolink:NamedThing	spongiotrophoblast layer developmental growth	The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state.	got7fsn_ti							tb	2010-01-08T12:10:44Z						biological_process											owl:Class	
GO:0061553	biolink:NamedThing	ganglion maturation	A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.	got7fsn_ti	ganglia maturation						dph	2013-07-10T08:45:59Z						biological_process											owl:Class	
GO:1990073	biolink:NamedThing	perforation plate	A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).	got7fsn_ti					Part of a vessel member (PO:0002003). May be simple, with one perforation, or multiperforate, with more than one perforation. Perforation plates are usually on the end walls of a cell, but may also be on the side walls.		tb	2013-03-29T00:53:28Z						cellular_component											owl:Class	
GO:0048929	biolink:NamedThing	efferent axon development in posterior lateral line nerve	The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0048918	biolink:NamedThing	posterior lateral line nerve development	The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.	got7fsn_ti	PLLN development|caudal lateral line nerve development										GO:0021733			biological_process											owl:Class	
GO:0060288	biolink:NamedThing	formation of a compartment boundary	Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.	got7fsn_ti	compartment boundary formation													biological_process											owl:Class	
CHEBI:30089	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033007	biolink:NamedThing	negative regulation of mast cell activation involved in immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.	got7fsn_ti	negative regulation of mast cell activation during immune response													biological_process											owl:Class	
GO:0110157	biolink:NamedThing	reelin complex	An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain.	got7fsn_ti							kmv	2019-07-15T15:10:58Z						cellular_component											owl:Class	
GO:0038026	biolink:NamedThing	reelin-mediated signaling pathway	A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	reelin-mediated signal transduction pathway|reelin-mediated signalling pathway|reeler-mediated signaling pathway						bf	2011-08-02T02:06:18Z						biological_process											owl:Class	
GO:0048265	biolink:NamedThing	response to pain	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.	got7fsn_ti	physiological response to pain										GO:0048267			biological_process											owl:Class	
GO:0042472	biolink:NamedThing	inner ear morphogenesis	The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.	got7fsn_ti														biological_process											owl:Class	
GO:0045830	biolink:NamedThing	positive regulation of isotype switching	Any process that activates or increases the frequency, rate or extent of isotype switching.	got7fsn_ti	up-regulation of isotype switching|stimulation of isotype switching|activation of isotype switching|positive regulation of class switch recombination|up regulation of isotype switching|positive regulation of isotype switch recombination|upregulation of isotype switching|positive regulation of class switching													biological_process											owl:Class	
GO:0071808	biolink:NamedThing	satellite fibril	An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section).	got7fsn_ti							mah	2010-09-03T03:42:14Z						cellular_component											owl:Class	
GO:0051887	biolink:NamedThing	regulation of timing of exogen	Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.	got7fsn_ti	regulation of exogen													biological_process											owl:Class	
GO:0031925	biolink:NamedThing	pyridoxal transmembrane transporter activity	Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti	pyridoxal transporter activity													molecular_function											owl:Class	
GO:1903090	biolink:NamedThing	pyridoxal transmembrane transport	The process in which pyridoxal is transported across a membrane.	got7fsn_ti							al	2014-06-03T10:41:13Z						biological_process											owl:Class	
GO:0044225	biolink:NamedThing	apical pole of neuron	Portion of a neuron cell soma closest to the point where the apical dendrite emerges.	got7fsn_ti							jl	2009-11-13T03:49:14Z				NIF_Subcellular:sao1186862860		cellular_component											owl:Class	
GO:0033579	biolink:NamedThing	protein galactosylation in endoplasmic reticulum	The addition of a galactose unit to a protein amino acid in the endoplasmic reticulum.	got7fsn_ti	protein amino acid galactosylation in ER|protein amino acid galactosylation in endoplasmic reticulum													biological_process											owl:Class	
GO:0007049	biolink:NamedThing	cell cycle	The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.	got7fsn_ti	cell-division cycle											Wikipedia:Cell_cycle		biological_process											owl:Class	
GO:0017133	biolink:NamedThing	mitochondrial electron transfer flavoprotein complex	A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.	got7fsn_ti														cellular_component											owl:Class	
GO:0006967	biolink:NamedThing	positive regulation of antifungal peptide biosynthetic process	Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis.	got7fsn_ti	up-regulation of antifungal peptide biosynthetic process|antifungal polypeptide induction|stimulation of antifungal peptide biosynthetic process|upregulation of antifungal peptide biosynthetic process|activation of antifungal peptide biosynthetic process|antifungal peptide induction|up regulation of antifungal peptide biosynthetic process													biological_process											owl:Class	
GO:0070720	biolink:NamedThing	Grb2-SHP-2 complex	A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.	got7fsn_ti	GRB2-SHP-2 complex, PDGF stimulated						mah	2009-06-10T05:08:21Z						cellular_component											owl:Class	
GO:1903401	biolink:NamedThing	L-lysine transmembrane transport	The directed movement of L-lysine across a membrane.	got7fsn_ti							pr	2014-09-01T13:45:56Z						biological_process											owl:Class	
GO:0001403	biolink:NamedThing	invasive growth in response to glucose limitation	A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	colony morphology				Note that this term should not be used to describe the invasion of host tissues by pathogenic organisms, which is described by the biological process term 'entry into host ; GO:0044409', nor should it be used to describe growth of diseased cells of an organism into the surrounding normal tissue, which is outside of the scope of GO.									biological_process											owl:Class	
GO:0003162	biolink:NamedThing	atrioventricular node development	The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system.	got7fsn_ti	AV node development						dph	2009-10-01T02:05:13Z						biological_process											owl:Class	
NCBITaxon:Union_0000007	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0055051	biolink:NamedThing	ATP-binding cassette (ABC) transporter complex, integrated substrate binding	A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a half transporter. Two half-transporters come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.	got7fsn_ti														cellular_component											owl:Class	
GO:0042329	biolink:NamedThing	structural constituent of collagen and cuticulin-based cuticle	The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans.	got7fsn_ti	structural constituent of cuticle													molecular_function											owl:Class	
GO:0030715	biolink:NamedThing	oocyte growth in germarium-derived egg chamber	The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0060342	biolink:NamedThing	photoreceptor inner segment membrane	The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.	got7fsn_ti														cellular_component											owl:Class	
GO:0007127	biolink:NamedThing	meiosis I	The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.	got7fsn_ti	meiosis I nuclear division											Wikipedia:Meiosis#Meiosis_I		biological_process											owl:Class	
GO:0031514	biolink:NamedThing	motile cilium	A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.	got7fsn_ti	motile primary cilium|motile cilia|nodal cilium|motile primary cilia|motile secondary cilium|microtubule-based flagellum										GO:0031512|GO:0009434			cellular_component											owl:Class	
GO:0015605	biolink:NamedThing	organophosphate ester transmembrane transporter activity	Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.	got7fsn_ti														molecular_function											owl:Class	
GO:0015748	biolink:NamedThing	organophosphate ester transport	The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds.	got7fsn_ti														biological_process											owl:Class	
GO:0045328	biolink:NamedThing	cytochrome P450 4A1-heme linkage	The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester.	got7fsn_ti	cytochrome P450 4A1-haem linkage											RESID:AA0324		biological_process											owl:Class	
GO:0072211	biolink:NamedThing	metanephric pyramids development	The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.	got7fsn_ti	metanephric renal medulla development|metanephric renal pyramid development|metanephric pyramid development|metanephric kidney pyramid development						mah	2010-03-18T01:04:51Z						biological_process											owl:Class	
GO:0061797	biolink:NamedThing	pH-gated chloride channel activity	A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.	got7fsn_ti							dph	2016-10-06T07:11:14Z						molecular_function											owl:Class	
GO:0035076	biolink:NamedThing	ecdysone receptor-mediated signaling pathway	The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex.	got7fsn_ti	ecdysone receptor-mediated signalling pathway													biological_process											owl:Class	
GO:0015012	biolink:NamedThing	heparan sulfate proteoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.	got7fsn_ti	heparan sulfate proteoglycan formation|heparan sulphate proteoglycan biosynthesis|heparin proteoglycan biosynthetic process|heparan sulfate proteoglycan anabolism|heparan sulfate proteoglycan biosynthesis|heparan sulphate proteoglycan biosynthetic process|heparan sulfate proteoglycan synthesis											RESID:AA0210		biological_process											owl:Class	
GO:0007351	biolink:NamedThing	tripartite regional subdivision	Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.	got7fsn_ti														biological_process											owl:Class	
GO:1903595	biolink:NamedThing	positive regulation of histamine secretion by mast cell	Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell.	got7fsn_ti	up-regulation of histamine secretion by mast cell|upregulation of histamine secretion by mast cell|activation of histamine secretion by mast cell|up regulation of histamine secretion by mast cell						als	2014-11-06T13:19:26Z						biological_process											owl:Class	
GO:0060281	biolink:NamedThing	regulation of oocyte development	Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0043485	biolink:NamedThing	endosome to pigment granule transport	The directed movement of substances from endosomes to pigment granules.	got7fsn_ti														biological_process											owl:Class	
GO:0051299	biolink:NamedThing	centrosome separation	The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.	got7fsn_ti														biological_process											owl:Class	
GO:0150104	biolink:NamedThing	transport across blood-brain barrier	The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.	got7fsn_ti	transport across blood brain barrier|transport across BBB						bc	2019-05-27T09:12:03Z						biological_process											owl:Class	
GO:0070039	biolink:NamedThing	rRNA (guanosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.	got7fsn_ti												Reactome:R-HSA-6793096|Reactome:R-HSA-6793122		molecular_function											owl:Class	
GO:0005825	biolink:NamedThing	half bridge of spindle pole body	Structure adjacent to the plaques of the spindle pole body.	got7fsn_ti														cellular_component											owl:Class	
GO:0035881	biolink:NamedThing	amacrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.	got7fsn_ti	amacrine neuron differentiation						bf	2011-06-06T11:32:50Z						biological_process											owl:Class	
GO:0017090	biolink:NamedThing	meprin A complex	A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.	got7fsn_ti	PABA peptide hydrolase complex													cellular_component											owl:Class	
GO:0015649	biolink:NamedThing	2-keto-3-deoxygluconate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in).	got7fsn_ti	2-keto-3-deoxygluconate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0046411	biolink:NamedThing	2-keto-3-deoxygluconate transmembrane transport	The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	2-keto-3-deoxygluconate transport													biological_process											owl:Class	
GO:1990720	biolink:NamedThing	C2 axonemal microtubule	One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections.	got7fsn_ti	C2 tubule						krc	2015-03-27T22:58:40Z						cellular_component											owl:Class	
GO:0009862	biolink:NamedThing	systemic acquired resistance, salicylic acid mediated signaling pathway	The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance.	got7fsn_ti	systemic acquired resistance, salicylic acid mediated signalling pathway|salicylic acid mediated signaling pathway (systemic acquired resistance)													biological_process											owl:Class	
GO:0060241	biolink:NamedThing	lysozyme inhibitor activity	Binds to and stops, prevents or reduces the activity of lysozyme.	got7fsn_ti														molecular_function											owl:Class	
GO:0015884	biolink:NamedThing	folic acid transport	The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.	got7fsn_ti	folate transport|vitamin M transport|vitamin B9 transport													biological_process											owl:Class	
GO:0060511	biolink:NamedThing	creation of an inductive signal by a mesenchymal cell involved in lung induction	The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud.	got7fsn_ti														biological_process											owl:Class	
GO:0046858	biolink:NamedThing	chlorosome	A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate.	got7fsn_ti												Wikipedia:Chlorosome		cellular_component											owl:Class	
GO:0035858	biolink:NamedThing	eosinophil fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	eosinophil cell fate determination						bf	2011-05-17T10:43:35Z						biological_process											owl:Class	
GO:1902939	biolink:NamedThing	negative regulation of intracellular calcium activated chloride channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity.	got7fsn_ti	down regulation of intracellular calcium activated chloride channel activity|down-regulation of intracellular calcium activated chloride channel activity|downregulation of intracellular calcium activated chloride channel activity|inhibition of intracellular calcium activated chloride channel activity						als	2014-04-28T08:49:14Z						biological_process											owl:Class	
GO:1990916	biolink:NamedThing	Isp3 layer of spore wall	The outermost layers of the spore wall, as described in Schizosaccharomyces pombe.	got7fsn_ti							al	2015-12-09T19:07:23Z						cellular_component											owl:Class	
GO:0021670	biolink:NamedThing	lateral ventricle development	The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.	got7fsn_ti														biological_process											owl:Class	
GO:0021591	biolink:NamedThing	ventricular system development	The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.	got7fsn_ti														biological_process											owl:Class	
GO:0032435	biolink:NamedThing	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	got7fsn_ti	down regulation of proteasomal ubiquitin-dependent protein catabolic process|inhibition of proteasomal ubiquitin-dependent protein catabolic process|downregulation of proteasomal ubiquitin-dependent protein catabolic process|down-regulation of proteasomal ubiquitin-dependent protein catabolic process													biological_process											owl:Class	
GO:0009554	biolink:NamedThing	megasporogenesis	The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus.	got7fsn_ti	megaspore mother cell meiosis|megaspore development|meiosis of the megasporocyte|meiotic division of the megasporocyte													biological_process											owl:Class	
GO:0000073	biolink:NamedThing	initial mitotic spindle pole body separation	The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB.	got7fsn_ti											GO:0030475			biological_process											owl:Class	
GO:1905047	biolink:NamedThing	mitotic spindle pole body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body.	got7fsn_ti							vw	2016-03-14T09:48:42Z						biological_process											owl:Class	
GO:0070830	biolink:NamedThing	bicellular tight junction assembly	The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.	got7fsn_ti	tight junction formation						mah	2009-07-23T04:32:38Z						biological_process											owl:Class	
GO:0001618	biolink:NamedThing	virus receptor activity	Combining with a virus component and mediating entry of the virus into the cell.	got7fsn_ti	viral receptor activity													molecular_function											owl:Class	
GO:0046718	biolink:NamedThing	viral entry into host cell	The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.	got7fsn_ti	virion penetration into host cell|virion penetration|virus entry into host cell|viral penetration|phage translocation|entry of virus into host cell				Viral attachment to the host cell is not part of viral entry in GO because virus attachment does not always lead to viral entry: attachment can also result in the virion being carried by the host cell to another location.						GO:0019063	VZ:936		biological_process											owl:Class	
GO:2001285	biolink:NamedThing	negative regulation of BMP secretion	Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion.	got7fsn_ti	negative regulation of BMP protein secretion|negative regulation of bone morphogenetic protein secretion						bf	2011-12-15T02:15:36Z						biological_process											owl:Class	
GO:0009897	biolink:NamedThing	external side of plasma membrane	The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	got7fsn_ti	juxtamembrane|outer surface of cytoplasmic membrane|external leaflet of plasma membrane													cellular_component											owl:Class	
GO:0071563	biolink:NamedThing	Myo2p-Vac17p-Vac8p transport complex	A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p.	got7fsn_ti							mah	2010-01-20T03:03:24Z						cellular_component											owl:Class	
GO:0021577	biolink:NamedThing	hindbrain structural organization	The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.	got7fsn_ti	hindbrain structural organisation													biological_process											owl:Class	
GO:0048908	biolink:NamedThing	anterior lateral line ganglion neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.	got7fsn_ti														biological_process											owl:Class	
GO:0010339	biolink:NamedThing	external side of cell wall	The side of the cell wall that is opposite to the side that faces the cell and its contents.	got7fsn_ti														cellular_component											owl:Class	
GO:1901388	biolink:NamedThing	regulation of transforming growth factor beta activation	Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.	got7fsn_ti	regulation of latent TGF-beta activation|regulation of TGFbeta activation|regulation of TGFB activation|regulation of L-TGF-beta activation|regulation of TGF-beta activation|regulation of TGF-B activation						bf	2012-10-01T10:32:00Z						biological_process											owl:Class	
GO:0071604	biolink:NamedThing	transforming growth factor beta production	The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.	got7fsn_ti	transforming growth factor-beta secretion|transforming growth factor-beta production|TGF-B production|TGF-beta production|TGFb production|TGFbeta production						mah	2010-02-05T03:56:57Z			GO:0038044			biological_process											owl:Class	
GO:0031600	biolink:NamedThing	cytosolic proteasome regulatory particle	A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0061214	biolink:NamedThing	mesonephric smooth muscle tissue development	The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-08-17T03:29:54Z						biological_process											owl:Class	
GO:0051417	biolink:NamedThing	microtubule nucleation by spindle pole body	The 'de novo' formation of a microtubule, mediated by the spindle pole body.	got7fsn_ti	microtubule nucleation by SPB|SPB-mediated microtubule nucleation|spindle pole body-mediated microtubule nucleation													biological_process											owl:Class	
GO:0007392	biolink:NamedThing	initiation of dorsal closure	Events that occur at the start of dorsal closure.	got7fsn_ti														biological_process											owl:Class	
GO:0007093	biolink:NamedThing	mitotic cell cycle checkpoint signaling	A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.	got7fsn_ti	signal transduction involved in mitotic cell cycle checkpoint|signal transduction involved in mitotic cell cycle G1/S checkpoint|signal transduction involved in mitotic G2/M transition checkpoint|mitotic checkpoint|mitotic cell cycle checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0031575|GO:0071780|GO:0072413|GO:0072456|GO:0072474			biological_process											owl:Class	
GO:0048935	biolink:NamedThing	peripheral nervous system neuron development	The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.	got7fsn_ti														biological_process											owl:Class	
GO:0005704	biolink:NamedThing	polytene chromosome band	A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band.	got7fsn_ti														cellular_component											owl:Class	
GO:0005700	biolink:NamedThing	polytene chromosome	A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.	got7fsn_ti												Wikipedia:Polytene_chromosome		cellular_component											owl:Class	
GO:0039703	biolink:NamedThing	RNA replication	The cellular metabolic process in which a cell duplicates one or more molecules of RNA.	got7fsn_ti							bf	2013-11-21T16:53:29Z						biological_process											owl:Class	
GO:0015277	biolink:NamedThing	kainate selective glutamate receptor activity	An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.	got7fsn_ti					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'.									molecular_function											owl:Class	
CHEBI:29101	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090654	biolink:NamedThing	basolateral recycling endosome	Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells.	got7fsn_ti							tb	2015-07-01T15:46:19Z						cellular_component											owl:Class	
GO:0110084	biolink:NamedThing	negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti							kmv	2018-02-01T19:33:51Z						biological_process											owl:Class	
GO:1903475	biolink:NamedThing	mitotic actomyosin contractile ring assembly	Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.	got7fsn_ti	actomyosin contractile ring assembly involved in cytokinesis after mitosis|contractile ring assembly involved in mitotic cytokinesis|cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis						vw	2014-09-23T14:42:12Z						biological_process											owl:Class	
GO:0003194	biolink:NamedThing	sinoatrial valve formation	The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti	SA valve formation						dph	2009-10-08T01:12:45Z						biological_process											owl:Class	
GO:0003185	biolink:NamedThing	sinoatrial valve morphogenesis	The process in which the structure of the sinoatrial valve is generated and organized.	got7fsn_ti	SA valve morphogenesis						dph	2009-10-08T12:04:52Z						biological_process											owl:Class	
GO:0042900	biolink:NamedThing	arabinose transmembrane transporter activity	Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015751	biolink:NamedThing	arabinose transmembrane transport	The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	arabinose transport													biological_process											owl:Class	
GO:0005744	biolink:NamedThing	TIM23 mitochondrial import inner membrane translocase complex	The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.	got7fsn_ti	mitochondrial inner membrane presequence translocase complex|Tim23 complex|mitochondrial inner membrane pre-sequence translocase complex|mitochondrial inner membrane translocase complex				See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.									cellular_component											owl:Class	
GO:0044156	biolink:NamedThing	host cell junction	A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.	got7fsn_ti							jl	2009-08-11T04:04:50Z						cellular_component											owl:Class	
GO:0020002	biolink:NamedThing	host cell plasma membrane	The plasma membrane surrounding a host cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0098828	biolink:NamedThing	modulation of inhibitory postsynaptic potential	Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.	got7fsn_ti	regulation of inhibitory postsynaptic potential													biological_process											owl:Class	
GO:1903389	biolink:NamedThing	negative regulation of synaptic vesicle uncoating	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating.	got7fsn_ti	down regulation of synaptic vesicle coat depolymerization|downregulation of synaptic vesicle coat protein depolymerization|down regulation of synaptic vesicle uncoating|negative regulation of synaptic vesicle coat depolymerization|negative regulation of synaptic vesicle coat protein depolymerization|downregulation of synaptic vesicle uncoating|down-regulation of synaptic vesicle coat depolymerization|down-regulation of synaptic vesicle coat protein depolymerization|down-regulation of synaptic vesicle uncoating|inhibition of synaptic vesicle coat depolymerization|downregulation of synaptic vesicle coat depolymerization|inhibition of synaptic vesicle uncoating|inhibition of synaptic vesicle coat protein depolymerization|down regulation of synaptic vesicle coat protein depolymerization						pad	2014-08-27T10:03:02Z						biological_process											owl:Class	
GO:0035670	biolink:NamedThing	plant-type ovary development	The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.	got7fsn_ti							bf	2011-02-04T09:35:05Z						biological_process											owl:Class	
GO:0048440	biolink:NamedThing	carpel development	The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.	got7fsn_ti											GO:0048429			biological_process											owl:Class	
GO:0030552	biolink:NamedThing	cAMP binding	Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).	got7fsn_ti	3',5' cAMP binding|adenosine 3',5'-cyclophosphate binding|3',5'-cAMP binding|cyclic AMP binding													molecular_function											owl:Class	
GO:0015085	biolink:NamedThing	calcium ion transmembrane transporter activity	Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-2534359		molecular_function											owl:Class	
GO:0071714	biolink:NamedThing	icosanoid transmembrane transporter activity	Enables the transfer of icosanoids from one side of a membrane to the other.	got7fsn_ti	eicosanoid transmembrane transporter activity						mah	2010-03-10T01:50:08Z						molecular_function											owl:Class	
GO:0071715	biolink:NamedThing	icosanoid transport	The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.	got7fsn_ti	eicosanoid transport						mah	2010-03-10T02:47:22Z						biological_process											owl:Class	
GO:1904693	biolink:NamedThing	midbrain morphogenesis	The developmental process by which a midbrain is generated and organized.	got7fsn_ti	MB morphogenesis|mesencephalon morphogenesis						bf	2015-09-29T09:15:28Z						biological_process											owl:Class	
GO:0007249	biolink:NamedThing	I-kappaB kinase/NF-kappaB signaling	The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.	got7fsn_ti	I-kappaB kinase/NF-kappaB cascade|canonical NF-kappaB signaling cascade|NF-kappaB cascade|p50-dependent NF-kappaB signaling|I-kappaB kinase/NF-kappaB signal transduction|activation of the inhibitor of kappa kinase													biological_process											owl:Class	
GO:0030082	biolink:NamedThing	B800-850 antenna complex	Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.	got7fsn_ti	light harvesting complex II|LH2 complex													cellular_component											owl:Class	
GO:0009577	biolink:NamedThing	elaioplast stroma	The space enclosed by the double membrane of an elaioplast.	got7fsn_ti														cellular_component											owl:Class	
GO:0048158	biolink:NamedThing	oogonium stage	The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.	got7fsn_ti	mammalian oogenesis stage 1													biological_process											owl:Class	
GO:0106074	biolink:NamedThing	aminoacyl-tRNA metabolism involved in translational fidelity	Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation.	got7fsn_ti	aminoacyl-tRNA editin|aminoacyl-tRNA proofreading|aminoacyl-tRNA correction						hjd	2017-11-29T17:48:39Z						biological_process											owl:Class	
GO:0050803	biolink:NamedThing	regulation of synapse structure or activity	Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).	got7fsn_ti														biological_process											owl:Class	
GO:1905692	biolink:NamedThing	endoplasmic reticulum disassembly	The disaggregation of an endoplasmic reticulum into its constituent components.	got7fsn_ti	ER disassembly						pr	2016-11-14T13:39:14Z						biological_process											owl:Class	
GO:2001259	biolink:NamedThing	positive regulation of cation channel activity	Any process that activates or increases the frequency, rate or extent of cation channel activity.	got7fsn_ti	positive regulation of cation diffusion facilitator activity|positive regulation of nonselective cation channel activity						vk	2011-12-07T07:14:57Z						biological_process											owl:Class	
GO:0021588	biolink:NamedThing	cerebellum formation	The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	got7fsn_ti														biological_process											owl:Class	
GO:2000803	biolink:NamedThing	endosomal signal transduction	The process in which a signal is passed on to downstream components located at the endosome. Endosomes can provide important intracellular signaling platforms and provide spatial and temporal control over signal transduction.	got7fsn_ti	signalling cascade in endosome|signaling pathway in endosome|signaling from endosome|endosome-based signaling|signalling pathway in endosome|signaling cascade in endosome						bf	2011-07-01T03:45:12Z						biological_process											owl:Class	
GO:0033367	biolink:NamedThing	protein localization to mast cell secretory granule	A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.	got7fsn_ti	protein localisation in mast cell secretory granule|protein localization in mast cell secretory granule													biological_process											owl:Class	
GO:0071065	biolink:NamedThing	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.	got7fsn_ti	ITGA9-ITGB1-VCAM1 complex						mah	2009-11-03T04:04:01Z						cellular_component											owl:Class	
GO:0005457	biolink:NamedThing	GDP-fucose transmembrane transporter activity	Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti												Reactome:R-HSA-5653596|Reactome:R-HSA-742345		molecular_function											owl:Class	
GO:0015783	biolink:NamedThing	GDP-fucose transmembrane transport	The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-fucose transport													biological_process											owl:Class	
GO:0015790	biolink:NamedThing	UDP-xylose transmembrane transport	The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-xylose transport													biological_process											owl:Class	
GO:0043684	biolink:NamedThing	type IV secretion system complex	A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s).	got7fsn_ti	type IV protein secretion system complex|T4SS complex													cellular_component											owl:Class	
GO:0009640	biolink:NamedThing	photomorphogenesis	The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis.	got7fsn_ti	plant development in response to light											Wikipedia:Photomorphogenesis		biological_process											owl:Class	
GO:0046727	biolink:NamedThing	capsomere	Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses.	got7fsn_ti	capsomer											Wikipedia:Capsomere		cellular_component											owl:Class	
GO:0019028	biolink:NamedThing	viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.	got7fsn_ti											GO:0046728	Wikipedia:Capsid		cellular_component											owl:Class	
GO:1903947	biolink:NamedThing	positive regulation of ventricular cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential.	got7fsn_ti	up regulation of ventricular cardiac muscle cell action potential|upregulation of ventricular cardiac muscle cell action potential|activation of ventricular cardiac muscle cell action potential|up-regulation of ventricular cardiac muscle cell action potential						nc	2015-02-20T14:32:04Z						biological_process											owl:Class	
GO:0010923	biolink:NamedThing	negative regulation of phosphatase activity	Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0016311	biolink:NamedThing	dephosphorylation	The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.	got7fsn_ti												Wikipedia:Dephosphorylation		biological_process											owl:Class	
GO:0039708	biolink:NamedThing	nuclear capsid assembly	The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly.	got7fsn_ti							bf	2013-11-28T15:08:41Z				VZ:1516		biological_process											owl:Class	
GO:0046594	biolink:NamedThing	maintenance of pole plasm mRNA location	The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	maintenance of oocyte pole plasm mRNA localization|maintenance of pole plasm mRNA localization										GO:0048122			biological_process											owl:Class	
GO:0060016	biolink:NamedThing	granulosa cell development	The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0060014	biolink:NamedThing	granulosa cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.	got7fsn_ti														biological_process											owl:Class	
GO:0034080	biolink:NamedThing	CENP-A containing nucleosome assembly	The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.	got7fsn_ti	CENP-A containing nucleosome assembly at centromere|DNA replication-independent nucleosome assembly at centromere|centromeric DNA replication-independent nucleosome assembly|centromere-specific histone exchange|centromere specific nucleosome exchange|CENP-A loading|CenH3-containing nucleosome assembly at centromere|CENP-A deposition										GO:0034509			biological_process											owl:Class	
GO:0002397	biolink:NamedThing	MHC class I protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0070993	biolink:NamedThing	translation preinitiation complex	A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA.	got7fsn_ti							mah	2009-10-30T01:25:00Z						cellular_component											owl:Class	
GO:0061265	biolink:NamedThing	mesonephric nephron tubule epithelial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.	got7fsn_ti							dph	2010-08-30T03:02:09Z						biological_process											owl:Class	
GO:0030726	biolink:NamedThing	male germline ring canal formation	Formation of the intercellular bridges that connect the germ-line cells of a male cyst.	got7fsn_ti	testicular ring canal formation|spermatocyte ring canal formation													biological_process											owl:Class	
GO:0001121	biolink:NamedThing	bacterial transcription	The synthesis of RNA from a DNA template by a bacterial-type RNA polymerase, originating at a bacterial-type promoter.	got7fsn_ti	transcription from bacterial-type RNA polymerase promoter	https://github.com/geneontology/go-ontology/issues/14854					krc	2010-12-06T03:32:13Z						biological_process											owl:Class	
GO:0071692	biolink:NamedThing	protein localization to extracellular region	Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.	got7fsn_ti	protein localization in extracellular region|protein localisation in extracellular region						mah	2010-02-25T04:00:13Z						biological_process											owl:Class	
GO:1902117	biolink:NamedThing	positive regulation of organelle assembly	Any process that activates or increases the frequency, rate or extent of organelle assembly.	got7fsn_ti	up-regulation of organelle assembly|activation of organelle assembly|upregulation of organelle assembly|up regulation of organelle assembly						pr	2013-05-14T09:43:36Z						biological_process											owl:Class	
GO:0033025	biolink:NamedThing	regulation of mast cell apoptotic process	Any process that modulates the frequency, rate, or extent of mast cell apoptotic process.	got7fsn_ti	regulation of mast cell apoptosis													biological_process											owl:Class	
GO:0045281	biolink:NamedThing	succinate dehydrogenase complex	A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones.	got7fsn_ti														cellular_component											owl:Class	
GO:0061840	biolink:NamedThing	high-affinity ferrous iron transmembrane transporter activity	Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity ferrous uptake transmembrane transporter activity|high-affinity ferrous iron uptake transmembrane transporter activity													molecular_function											owl:Class	
GO:0002526	biolink:NamedThing	acute inflammatory response	Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.	got7fsn_ti														biological_process											owl:Class	
GO:0060126	biolink:NamedThing	somatotropin secreting cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.	got7fsn_ti	somatotrophin secreting cell differentiation|somatotrope differentiation|somatotroph differentiation|somatrophic cell differentiation|somatotropic cell differentiation|growth hormone secreting cell differentiation													biological_process											owl:Class	
GO:1903059	biolink:NamedThing	regulation of protein lipidation	Any process that modulates the frequency, rate or extent of protein lipidation.	got7fsn_ti	regulation of protein amino acid lipidation|regulation of lipid:protein modification						rph	2014-05-28T13:21:18Z						biological_process											owl:Class	
GO:0042157	biolink:NamedThing	lipoprotein metabolic process	The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.	got7fsn_ti	lipoprotein metabolism													biological_process											owl:Class	
GO:0006408	biolink:NamedThing	snRNA export from nucleus	The directed movement of snRNA from the nucleus to the cytoplasm.	got7fsn_ti	snRNA transport from nucleus to cytoplasm|snRNA-nucleus export|snRNA export out of nucleus|snRNA export from cell nucleus													biological_process											owl:Class	
GO:0035964	biolink:NamedThing	COPI-coated vesicle budding	The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.	got7fsn_ti	COPI vesicle budding						bf	2011-08-01T11:32:23Z						biological_process											owl:Class	
GO:0009578	biolink:NamedThing	etioplast stroma	The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA.	got7fsn_ti														cellular_component											owl:Class	
GO:0009533	biolink:NamedThing	chloroplast stromal thylakoid	Unstacked thylakoids that connect the grana stacks through the stroma.	got7fsn_ti														cellular_component											owl:Class	
GO:0010377	biolink:NamedThing	guard cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere.	got7fsn_ti	stomatal cell fate commitment													biological_process											owl:Class	
GO:0140673	biolink:NamedThing	co-transcriptional chromatin reassembly	The reestablishment of chromatin structure that was disrupted upon passage of RNA polymerase II during transcription elongation. This process prevents cryptic intragenic transcription initiation.	got7fsn_ti	maintainance of chromatin integrity during transcription elongation by RNAPII|euchromatin maintenance during transcription elongation|chromatin maintenance during transcription elongation|maintenance of transcriptionally active chromatin during transcription elongation	https://github.com/geneontology/go-ontology/issues/21730			Note: Do not confuse with GO:0048096 chromatin-mediated maintenance of transcription, which describes the maintenance of chromatin in an open conformation (indeendent of transcription).		pg	2021-06-29T09:18:46Z						biological_process											owl:Class	
GO:0007421	biolink:NamedThing	stomatogastric nervous system development	The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0015628	biolink:NamedThing	protein secretion by the type II secretion system	The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.	got7fsn_ti	protein secretion by the type II protein secretion system|protein secretion by the T2SS|protein secretion by the T2S|protein secretion by the general secretory pathway|type II protein secretion system|protein secretion by the general secretion pathway				Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type II protein secretion system complex ; GO:0015627'. This process refers specifically to secretion across the outer membrane. For components of the Sec and Tat pathways, consider annotating to 'protein transport by the Sec complex ; GO:0043952' and 'protein transport by the Tat complex ; GO:0043953'. Note that this term is used for annotation of proteins that compose the secretion complex but not the proteins being secreted.									biological_process											owl:Class	
GO:0097745	biolink:NamedThing	mitochondrial tRNA 5'-end processing	The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.	got7fsn_ti							pr	2016-11-08T10:50:51Z						biological_process											owl:Class	
GO:0048759	biolink:NamedThing	xylem vessel member cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.	got7fsn_ti	vessel element cell differentiation|vessel member cell differentiation													biological_process											owl:Class	
GO:0010089	biolink:NamedThing	xylem development	The formation of the principal water-conducting tissue of a vascular plant.	got7fsn_ti	xylem histogenesis													biological_process											owl:Class	
GO:0004906	biolink:NamedThing	interferon-gamma receptor activity	Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	type II interferon receptor activity|IFNG receptor activity|IFN-gamma receptor activity													molecular_function											owl:Class	
GO:0019964	biolink:NamedThing	interferon-gamma binding	Binding to interferon-gamma. Interferon gamma is the only member of the type II interferon found so far.	got7fsn_ti	IFN-gamma binding|type II interferon binding|IFNG binding													molecular_function											owl:Class	
GO:0031586	biolink:NamedThing	negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.	got7fsn_ti	downregulation of IP3 receptor activity|down-regulation of IP3 receptor activity|down regulation of IP3 receptor activity|negative regulation of inositol 1,4,5-trisphosphate receptor activity|inhibition of IP3 receptor activity|negative regulation of IP3 receptor activity													biological_process											owl:Class	
GO:0071022	biolink:NamedThing	U12-type post-spliceosomal complex	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.	got7fsn_ti	mammalian U12-type spliceosomal complex C2|minor post-spliceosomal complex|AT-AC post-spliceosomal complex|yeast U12-type spliceosomal complex A2-3						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0014816	biolink:NamedThing	skeletal muscle satellite cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.	got7fsn_ti														biological_process											owl:Class	
GO:1900144	biolink:NamedThing	positive regulation of BMP secretion	Any process that activates or increases the frequency, rate or extent of BMP secretion.	got7fsn_ti	up-regulation of BMP secretion|up regulation of bone morphogenetic protein secretion|up-regulation of bone morphogenetic protein secretion|activation of BMP secretion|activation of bone morphogenetic protein secretion|upregulation of bone morphogenetic protein secretion|up regulation of BMP protein secretion|upregulation of BMP secretion|positive regulation of BMP protein secretion|up regulation of BMP secretion|upregulation of BMP protein secretion|positive regulation of bone morphogenetic protein secretion|up-regulation of BMP protein secretion|activation of BMP protein secretion						sart	2012-03-06T10:31:47Z						biological_process											owl:Class	
GO:0042008	biolink:NamedThing	interleukin-18 receptor activity	Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-18 receptor activity|IL-18R													molecular_function											owl:Class	
GO:0042007	biolink:NamedThing	interleukin-18 binding	Binding to interleukin-18.	got7fsn_ti	IL-18 binding													molecular_function											owl:Class	
GO:0009433	biolink:NamedThing	bacterial-type flagellum basal body, C ring	Cytoplasmic ring located at the base of the bacterial-type flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise.	got7fsn_ti	flagellar basal body, C ring|flagellin-based flagellum basal body, C ring													cellular_component											owl:Class	
GO:0016528	biolink:NamedThing	sarcoplasm	The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.	got7fsn_ti												Wikipedia:Sarcoplasm		cellular_component											owl:Class	
GO:0031629	biolink:NamedThing	synaptic vesicle fusion to presynaptic active zone membrane	Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.	got7fsn_ti	synaptic vesicle fusion to presynaptic membrane|synaptic vesicle fusion|synaptic vesicle fusion to pre-synaptic membrane													biological_process											owl:Class	
GO:0051386	biolink:NamedThing	regulation of neurotrophin TRK receptor signaling pathway	Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.	got7fsn_ti	regulation of NGF receptor signaling pathway|regulation of NGF receptor signalling pathway|regulation of nerve growth factor receptor signalling pathway|regulation of nerve growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0009291	biolink:NamedThing	unidirectional conjugation	The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. Examples of this process are found in prokaryotes.	got7fsn_ti														biological_process											owl:Class	
GO:0044520	biolink:NamedThing	envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.	got7fsn_ti	envenomation resulting in positive regulation of VIP receptor activity in other organism						jl	2012-02-26T11:55:46Z						biological_process											owl:Class	
GO:0019531	biolink:NamedThing	oxalate transmembrane transporter activity	Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.	got7fsn_ti	oxalic acid transporter activity													molecular_function											owl:Class	
GO:0019532	biolink:NamedThing	oxalate transport	The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.	got7fsn_ti	ethanedioic acid transport|ethanedioate transport|oxalic acid transport													biological_process											owl:Class	
NCBITaxon:4762	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090688	biolink:NamedThing	cleavage furrow rim	The part of the cleavage furrow closest to the cell surface.	got7fsn_ti							tb	2016-07-26T16:00:10Z						cellular_component											owl:Class	
GO:0033315	biolink:NamedThing	meiotic G2/MI DNA replication checkpoint signaling	A signal transduction process that controls the G2/M1 transition of the meiotic cell cycle and prevents the initiation of nuclear division until DNA replication is complete.	got7fsn_ti	meiotic cell cycle DNA replication checkpoint|meiotic G2/MI DNA replication checkpoint|signal transduction involved in meiotic DNA replication checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072440			biological_process											owl:Class	
GO:0008315	biolink:NamedThing	G2/MI transition of meiotic cell cycle	The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I.	got7fsn_ti	meiotic cell cycle G2/MI phase transition|meiotic G2/MI phase transition|meiotic G2/MI transition													biological_process											owl:Class	
GO:0046612	biolink:NamedThing	lysosomal proton-transporting V-type ATPase, V1 domain	The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.	got7fsn_ti	lysosomal hydrogen ion-transporting ATPase V1 domain													cellular_component											owl:Class	
GO:0046611	biolink:NamedThing	lysosomal proton-transporting V-type ATPase complex	A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen.	got7fsn_ti	lysosomal membrane hydrogen-transporting ATPase|lysosomal hydrogen-translocating V-type ATPase complex													cellular_component											owl:Class	
GO:0070519	biolink:NamedThing	alpha4-beta1 integrin-CD63 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family.	got7fsn_ti	ITGA4-ITGB1-CD63 complex													cellular_component											owl:Class	
GO:0001699	biolink:NamedThing	acetylcholine-induced gastric acid secretion	The regulated release of gastric acid by parietal cells in response to acetylcholine.	got7fsn_ti														biological_process											owl:Class	
GO:0090299	biolink:NamedThing	regulation of neural crest formation	Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.	got7fsn_ti							tb	2010-03-12T04:08:26Z						biological_process											owl:Class	
GO:1905297	biolink:NamedThing	positive regulation of neural crest cell fate specification	Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification.	got7fsn_ti	up-regulation of neural crest cell fate specification|upregulation of neural crest cell fate specification|activation of neural crest cell fate specification|up regulation of neural crest cell fate specification						rl	2016-06-28T15:14:57Z						biological_process											owl:Class	
GO:1904785	biolink:NamedThing	regulation of asymmetric protein localization involved in cell fate determination	Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.	got7fsn_ti	regulation of asymmetric protein localisation involved in cell fate determination|regulation of asymmetric protein localization resulting in cell fate commitment|regulation of asymmetric protein localization involved in cell fate commitment|regulation of cell fate commitment, asymmetric protein localization				wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP)		es	2015-11-03T12:11:06Z						biological_process											owl:Class	
GO:0035288	biolink:NamedThing	anterior head segmentation	Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.	got7fsn_ti	procephalic segmentation				See also the fly_anatomy.ontology term 'procephalic segment ; FBbt:00000007' and its children.									biological_process											owl:Class	
GO:0097065	biolink:NamedThing	anterior head development	The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure.	got7fsn_ti							pr	2011-06-08T12:38:11Z						biological_process											owl:Class	
GO:0098561	biolink:NamedThing	methyl accepting chemotaxis protein complex	A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus.	got7fsn_ti					A number of complexes of this class are found in E.coli.									cellular_component											owl:Class	
GO:2000709	biolink:NamedThing	regulation of maintenance of meiotic sister chromatid cohesion, centromeric	Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.	got7fsn_ti	regulation of maintenance of meiotic sister chromatin cohesion at centromere|regulation of maintenance of centromeric meiotic sister chromatin cohesion|regulation of maintenance of sister chromatin cohesion at centromere at meiosis I						mah	2011-06-01T12:41:11Z						biological_process											owl:Class	
GO:0038144	biolink:NamedThing	ERBB4:ERBB2 complex	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.	got7fsn_ti	ERBB4:ERBB2 heterodimer|NRGs/EGFLs:ERBB4:ERBB2						bf	2012-03-30T02:24:01Z						cellular_component											owl:Class	
GO:0022620	biolink:NamedThing	vegetative cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a vegetative cell. The vegetative cell is gives rise to the pollen tube.	got7fsn_ti	tube cell differentiation													biological_process											owl:Class	
GO:0106093	biolink:NamedThing	EDS1 disease-resistance complex	A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes.	got7fsn_ti	EDS1-SAG101 complex|EDS1-PAD4 complex|EDS1-PAD4-SAG101 complex				Interacts with the R genes triggering ETI and systemic resistance.		hjd	2018-01-29T20:02:47Z						cellular_component											owl:Class	
GO:0001507	biolink:NamedThing	acetylcholine catabolic process in synaptic cleft	The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission.	got7fsn_ti	acetylcholine breakdown in synaptic cleft|acetylcholine degradation in synaptic cleft													biological_process											owl:Class	
GO:0048286	biolink:NamedThing	lung alveolus development	The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.	got7fsn_ti	alveolarization|alveologenesis													biological_process											owl:Class	
GO:1990936	biolink:NamedThing	vascular associated smooth muscle cell dedifferentiation	The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.	got7fsn_ti	vascular smooth muscle cell dedifferentiation						tb	2016-03-22T20:25:11Z						biological_process											owl:Class	
GO:0052606	biolink:NamedThing	chlorophyllide a oxygenase activity	Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O.	got7fsn_ti	chlorophyll a oxygenase activity|chlorophyllide a:oxygen 7-oxidoreductase activity|chlorophyllide-a oxygenase activity|CAO activity											RHEA:22676|KEGG_REACTION:R08203|MetaCyc:RXN-7676		molecular_function											owl:Class	
GO:1903623	biolink:NamedThing	negative regulation of RNA polymerase III activity	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity.	got7fsn_ti	downregulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down-regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|downregulation of RNA polymerase III activity|inhibition of RNA polymerase III activity|negative regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down regulation of RNA polymerase III activity|down-regulation of RNA polymerase III activity|inhibition of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter						al	2014-11-19T18:24:37Z						biological_process											owl:Class	
GO:0061604	biolink:NamedThing	molybdopterin-synthase sulfurtransferase activity	Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine <=> AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase.	got7fsn_ti							dph	2014-02-11T11:56:16Z				EC:2.8.1.11|RHEA:48612		molecular_function											owl:Class	
CHEBI:64628	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043402	biolink:NamedThing	glucocorticoid mediated signaling pathway	A series of molecular signals mediated by the detection of a glucocorticoid hormone.	got7fsn_ti	glucocorticoid mediated signalling													biological_process											owl:Class	
GO:0071385	biolink:NamedThing	cellular response to glucocorticoid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.	got7fsn_ti							mah	2009-12-11T03:53:56Z						biological_process											owl:Class	
GO:2000301	biolink:NamedThing	negative regulation of synaptic vesicle exocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis.	got7fsn_ti							dph	2011-01-03T08:21:00Z						biological_process											owl:Class	
GO:0051256	biolink:NamedThing	mitotic spindle midzone assembly	The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.	got7fsn_ti	spindle midzone formation involved in mitosis|spindle midzone assembly involved in mitosis|mitotic spindle midzone biogenesis|mitotic spindle midzone biosynthesis|mitotic spindle midzone formation|spindle midzone biogenesis involved in mitosis													biological_process											owl:Class	
GO:0005865	biolink:NamedThing	striated muscle thin filament	Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0030017	biolink:NamedThing	sarcomere	The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	got7fsn_ti												Wikipedia:Sarcomere		cellular_component											owl:Class	
GO:0098774	biolink:NamedThing	curli	A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization.	got7fsn_ti	thin aggregative fimbrae|tafi													cellular_component											owl:Class	
GO:0097311	biolink:NamedThing	bacterial biofilm matrix	A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.	got7fsn_ti							pr	2012-05-24T11:20:50Z						cellular_component											owl:Class	
GO:1990876	biolink:NamedThing	cytoplasmic side of nuclear pore	The side of the nuclear pore complex (NPC) that faces the cytoplasm.	got7fsn_ti	cytoplasmic side of NPC|cytoplasmic side of nucleopore|cytoplasmic side of nuclear pore complex						sl	2015-10-01T21:47:54Z						cellular_component											owl:Class	
GO:0051294	biolink:NamedThing	establishment of spindle orientation	Any process that set the alignment of spindle relative to other cellular structures.	got7fsn_ti	spindle orientation|orienting of spindle													biological_process											owl:Class	
GO:0021530	biolink:NamedThing	spinal cord oligodendrocyte cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway.	got7fsn_ti														biological_process											owl:Class	
GO:0036179	biolink:NamedThing	osteoclast maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.	got7fsn_ti	chondroclast maturation						bf	2012-03-29T02:04:00Z						biological_process											owl:Class	
GO:0070718	biolink:NamedThing	alphaPDGFR-SHP-2 complex	A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.	got7fsn_ti	PDGFRA-SHP-2 complex, PDGF stimulated						mah	2009-06-10T05:00:43Z						cellular_component											owl:Class	
GO:1990633	biolink:NamedThing	mutator focus	A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules.	got7fsn_ti							kmv	2015-02-10T20:24:02Z						cellular_component											owl:Class	
GO:0044207	biolink:NamedThing	translation initiation ternary complex	A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).	got7fsn_ti	Met-tRNA/eIF2.GTP ternary complex|translation initiation (ternary) complex						jl	2009-10-22T02:38:55Z						cellular_component											owl:Class	
GO:0002246	biolink:NamedThing	wound healing involved in inflammatory response	The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.	got7fsn_ti	healing during inflammatory response|inflammatory response wound healing													biological_process											owl:Class	
GO:0090594	biolink:NamedThing	inflammatory response to wounding	The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.	got7fsn_ti							tb	2014-08-12T12:13:53Z						biological_process											owl:Class	
GO:0086062	biolink:NamedThing	voltage-gated sodium channel activity involved in Purkinje myocyte action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti							dph	2011-11-17T01:50:43Z						molecular_function											owl:Class	
GO:1905300	biolink:NamedThing	positive regulation of intestinal epithelial cell development	Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development.	got7fsn_ti	up-regulation of intestinal epithelial cell development|upregulation of intestinal epithelial cell development|activation of intestinal epithelial cell development|up regulation of intestinal epithelial cell development						rph	2016-06-30T11:41:02Z						biological_process											owl:Class	
GO:1901892	biolink:NamedThing	negative regulation of cell septum assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly.	got7fsn_ti	down regulation of cell septum assembly|down-regulation of cell septum assembly|downregulation of cell septum assembly|inhibition of cell septum assembly						tb	2013-02-06T20:14:45Z						biological_process											owl:Class	
GO:0002297	biolink:NamedThing	T-helper 2 cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.	got7fsn_ti	T-helper 2 cell fate commitment|Th2 fate commitment													biological_process											owl:Class	
GO:0045064	biolink:NamedThing	T-helper 2 cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4.	got7fsn_ti	T-helper 2 cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0043493	biolink:NamedThing	viral terminase complex	A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides.	got7fsn_ti	virus terminase complex|phage terminase complex													cellular_component											owl:Class	
GO:0017177	biolink:NamedThing	glucosidase II complex	A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins.	got7fsn_ti	alpha-glucosidase II complex				Note that alpha-glucosidase I functions as a monomer, and therefore does not have a corresponding cellular component term.									cellular_component											owl:Class	
GO:0090661	biolink:NamedThing	box H/ACA telomerase RNP complex	A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell.	got7fsn_ti							tb	2015-09-21T14:46:16Z						cellular_component											owl:Class	
GO:0032212	biolink:NamedThing	positive regulation of telomere maintenance via telomerase	Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.	got7fsn_ti	upregulation of telomere maintenance via telomerase activity|up regulation of telomere maintenance via telomerase activity|stimulation of telomere maintenance via telomerase|up-regulation of telomere maintenance via telomerase activity|activation of telomere maintenance via telomerase													biological_process											owl:Class	
GO:0060856	biolink:NamedThing	establishment of blood-brain barrier	Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.	got7fsn_ti	establishment of blood/brain barrier|establishment of BBB						dph	2009-08-12T12:12:59Z						biological_process											owl:Class	
GO:0035565	biolink:NamedThing	regulation of pronephros size	Any process that modulates the size of a pronephric kidney.	got7fsn_ti	regulation of pronephric kidney size						bf	2010-07-23T11:28:57Z						biological_process											owl:Class	
GO:0052721	biolink:NamedThing	regulation of apurinic/apyrimidinic endodeoxyribonuclease activity	Any process that modulates the frequency, rate or extent of apurinic/apyrimidinic (AP) endodeoxyribonuclease activity, the hydrolysis of ester linkages immediately 5' to an AP (also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	got7fsn_ti	regulation of abasic endodeoxyribonuclease activity|regulation of apurinic endodeoxyribonuclease activity|regulation of apyrimidinic endodeoxyribonuclease activity|regulation of AP endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0120273	biolink:NamedThing	ciliary centrin arm assembly	The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.	got7fsn_ti	ciliary centrin arm formation	https://github.com/geneontology/go-ontology/issues/20088					krc	2020-10-08T23:01:46Z						biological_process											owl:Class	
GO:0005795	biolink:NamedThing	Golgi stack	The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.	got7fsn_ti	dictyosome|Golgi cisternae										GO:0016940			cellular_component											owl:Class	
GO:0036101	biolink:NamedThing	leukotriene B4 catabolic process	The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.	got7fsn_ti	LTB4 catabolism|leukotriene B4 breakdown|leukotriene B4 catabolism|leukotriene B4 degradation						bf	2012-01-27T01:26:24Z						biological_process											owl:Class	
GO:0009553	biolink:NamedThing	embryo sac development	The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate.	got7fsn_ti	female gametophyte development										GO:0048230			biological_process											owl:Class	
GO:0010260	biolink:NamedThing	animal organ senescence	The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism.	got7fsn_ti											GO:0010261			biological_process											owl:Class	
GO:0042470	biolink:NamedThing	melanosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.	got7fsn_ti												Wikipedia:Melanosome		cellular_component											owl:Class	
GO:0036504	biolink:NamedThing	Golgi membrane fusion	The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane.	got7fsn_ti	post-mitotic fusion of Golgi membranes|membrane fusion involved in Golgi reassembly						bf	2015-05-21T10:05:06Z						biological_process											owl:Class	
GO:0090168	biolink:NamedThing	Golgi reassembly	The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.	got7fsn_ti							tb	2009-12-08T09:15:11Z						biological_process											owl:Class	
GO:0042773	biolink:NamedThing	ATP synthesis coupled electron transport	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.	got7fsn_ti														biological_process											owl:Class	
GO:0048916	biolink:NamedThing	posterior lateral line development	The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.	got7fsn_ti	PLL development													biological_process											owl:Class	
GO:0021783	biolink:NamedThing	preganglionic parasympathetic fiber development	The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.	got7fsn_ti														biological_process											owl:Class	
GO:0021607	biolink:NamedThing	accessory nerve morphogenesis	The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	got7fsn_ti	CN XI morphogenesis													biological_process											owl:Class	
GO:0021565	biolink:NamedThing	accessory nerve development	The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	got7fsn_ti	CN XI development|cranial nerve 11 development|cranial nerve XI development|spinal accessory nerve development													biological_process											owl:Class	
GO:0021697	biolink:NamedThing	cerebellar cortex formation	The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	got7fsn_ti														biological_process											owl:Class	
GO:0021574	biolink:NamedThing	rhombomere 8 development	The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0021896	biolink:NamedThing	forebrain astrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.	got7fsn_ti														biological_process											owl:Class	
GO:0032585	biolink:NamedThing	multivesicular body membrane	The lipid bilayer surrounding a multivesicular body.	got7fsn_ti	MVB membrane|multivesicular endosome membrane|MVE membrane													cellular_component											owl:Class	
GO:0048342	biolink:NamedThing	paraxial mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell.	got7fsn_ti														biological_process											owl:Class	
GO:0009576	biolink:NamedThing	leucoplast stroma	The space enclosed by the double membrane of a leucoplast.	got7fsn_ti														cellular_component											owl:Class	
NCBITaxon:32443	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007355	biolink:NamedThing	anterior region determination	Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.	got7fsn_ti														biological_process											owl:Class	
GO:0120224	biolink:NamedThing	larynx development	The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.	got7fsn_ti							krc	2020-02-24T17:13:10Z						biological_process											owl:Class	
GO:0061914	biolink:NamedThing	negative regulation of growth plate cartilage chondrocyte proliferation	Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.	got7fsn_ti							dph	2017-07-10T17:39:17Z						biological_process											owl:Class	
GO:0035265	biolink:NamedThing	organ growth	The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.	got7fsn_ti														biological_process											owl:Class	
GO:0003246	biolink:NamedThing	embryonic cardiac muscle cell growth involved in heart morphogenesis	The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart.	got7fsn_ti	embryonic cardiac muscle physiological hypertrophy						dph	2009-10-13T11:46:23Z						biological_process											owl:Class	
GO:0003245	biolink:NamedThing	cardiac muscle tissue growth involved in heart morphogenesis	The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.	got7fsn_ti							dph	2009-10-13T11:44:21Z						biological_process											owl:Class	
GO:0021659	biolink:NamedThing	rhombomere 3 structural organization	The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti	rhombomere 3 structural organisation													biological_process											owl:Class	
GO:0015179	biolink:NamedThing	L-amino acid transmembrane transporter activity	Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.	got7fsn_ti	L-amino acid transporter activity											Reactome:R-HSA-212614		molecular_function											owl:Class	
GO:1902475	biolink:NamedThing	L-alpha-amino acid transmembrane transport	The directed movement of L-alpha-amino acid across a membrane.	got7fsn_ti							kmv	2013-10-25T15:17:39Z						biological_process											owl:Class	
GO:1990527	biolink:NamedThing	Tec1p-Ste12p-Dig1p complex	A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae.	got7fsn_ti							rb	2014-11-05T22:55:17Z						cellular_component											owl:Class	
GO:0007532	biolink:NamedThing	regulation of mating-type specific transcription, DNA-templated	Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	got7fsn_ti	regulation of mating-type specific transcription, DNA-dependent|mating-type specific transcriptional control													biological_process											owl:Class	
GO:1902618	biolink:NamedThing	cellular response to fluoride	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.	got7fsn_ti							kmv	2014-01-10T19:41:58Z						biological_process											owl:Class	
GO:0045137	biolink:NamedThing	development of primary sexual characteristics	The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.	got7fsn_ti														biological_process											owl:Class	
GO:1900257	biolink:NamedThing	negative regulation of beta1-adrenergic receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of beta1-adrenergic receptor activity.	got7fsn_ti	down-regulation of beta1-adrenergic receptor activity|inhibition of beta1 adrenoceptor|down regulation of beta1 adrenoceptor|downregulation of beta1-adrenergic receptor activity|down-regulation of beta1 adrenoceptor|negative regulation of beta1 adrenoceptor|down regulation of beta1-adrenergic receptor activity|downregulation of beta1 adrenoceptor|inhibition of beta1-adrenergic receptor activity						tb	2012-04-03T10:59:40Z						biological_process											owl:Class	
GO:0044614	biolink:NamedThing	nuclear pore cytoplasmic filaments	Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.	got7fsn_ti	cytoplasmic fibers of the nuclear pore complex|cytoplasmic fibers of the NPC						jl	2012-06-20T01:28:18Z						cellular_component											owl:Class	
GO:1903934	biolink:NamedThing	positive regulation of DNA primase activity	Any process that activates or increases the frequency, rate or extent of DNA primase activity.	got7fsn_ti	up regulation of DNA primase activity|upregulation of DNA primase activity|activation of DNA primase activity|up-regulation of DNA primase activity						mah	2015-02-12T14:28:45Z						biological_process											owl:Class	
GO:2001258	biolink:NamedThing	negative regulation of cation channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity.	got7fsn_ti	negative regulation of nonselective cation channel activity|negative regulation of cation diffusion facilitator activity						vk	2011-12-07T07:14:51Z						biological_process											owl:Class	
GO:0021754	biolink:NamedThing	facial nucleus development	The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0060502	biolink:NamedThing	epithelial cell proliferation involved in lung morphogenesis	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.	got7fsn_ti														biological_process											owl:Class	
GO:0003231	biolink:NamedThing	cardiac ventricle development	The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.	got7fsn_ti							dph	2009-10-13T11:03:16Z						biological_process											owl:Class	
GO:0008079	biolink:NamedThing	translation termination factor activity	Functions in the termination of translation.	got7fsn_ti														molecular_function											owl:Class	
GO:0005635	biolink:NamedThing	nuclear envelope	The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).	got7fsn_ti											GO:0005636	Wikipedia:Nuclear_envelope		cellular_component											owl:Class	
GO:0021838	biolink:NamedThing	motogenic signaling involved in interneuron migration from the subpallium to the cortex	The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex.	got7fsn_ti	motogenic signalling involved in interneuron migration from the subpallium to the cortex													biological_process											owl:Class	
GO:0007502	biolink:NamedThing	digestive tract mesoderm development	The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism.	got7fsn_ti														biological_process											owl:Class	
GO:0045270	biolink:NamedThing	plasma membrane proton-transporting ATP synthase, central stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis. Examples of this component are found in Bacterial species.	got7fsn_ti	hydrogen-transporting ATP synthase, central stalk|proton-transporting ATP synthase, central stalk													cellular_component											owl:Class	
GO:0061440	biolink:NamedThing	kidney vasculature development	The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.	got7fsn_ti							dph	2012-03-08T12:39:09Z						biological_process											owl:Class	
GO:0000156	biolink:NamedThing	phosphorelay response regulator activity	Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.	got7fsn_ti	two-component response regulator activity	https://github.com/geneontology/go-ontology/issues/15611												molecular_function											owl:Class	
GO:0000160	biolink:NamedThing	phosphorelay signal transduction system	A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.	got7fsn_ti	phosphorelay signal transduction system|histidyl-aspartyl phosphorelay													biological_process											owl:Class	
GO:0005381	biolink:NamedThing	iron ion transmembrane transporter activity	Enables the transfer of iron (Fe) ions from one side of a membrane to the other.	got7fsn_ti	transmembrane iron ion permease activity|iron transporter activity|iron channel activity|transmembrane iron permease activity|multicopper ferroxidase iron transport mediator activity|iron cation channel activity|zinc, iron permease activity	https://github.com/geneontology/go-ontology/issues/17162			An example of this is mouse ferroportin (UniProtKB:Q9JHI9), which transports iron out of the cell.						GO:0016033|GO:0097689|GO:0005382	Reactome:R-HSA-5655733|Reactome:R-HSA-435349|Reactome:R-HSA-5623558|Reactome:R-HSA-917936|Reactome:R-HSA-904830		molecular_function											owl:Class	
GO:0014056	biolink:NamedThing	regulation of acetylcholine secretion, neurotransmission	Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.	got7fsn_ti														biological_process											owl:Class	
GO:0036162	biolink:NamedThing	oxytocin production	The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain.	got7fsn_ti	oxytocin secretion|oxytocin biosynthesis	https://github.com/geneontology/go-ontology/issues/9542|https://github.com/geneontology/go-ontology/issues/21535			Note that this term is intended for use when a gene product is seen to cause apparent increases in intracellular or extracellular oxytocin levels, without specific regard as to whether the increase is due to increased biosynthesis, increased secretion of preexisting oxytocin molecules, or increased conversion from precursor molecules.		bf	2012-03-26T01:43:46Z						biological_process											owl:Class	
GO:1903799	biolink:NamedThing	negative regulation of production of miRNAs involved in gene silencing by miRNA	Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.	got7fsn_ti	downregulation of microRNA biosynthetic process|down-regulation of microRNA metabolism|negative regulation of microRNA biosynthesis|down regulation of miRNA-mediated gene silencing, production of miRNAs|inhibition of production of miRNAs involved in gene silencing by miRNA|negative regulation of miRNA-mediated gene silencing, production of miRNAs|downregulation of microRNA metabolic process|downregulation of microRNA biogenesis|inhibition of miRNA-mediated gene silencing, production of miRNAs|downregulation of production of microRNAs involved in gene silencing by microRNA|negative regulation of production of microRNAs involved in gene silencing by microRNA|down-regulation of miRNA processing|down regulation of gene silencing by miRNA, production of miRNAs|negative regulation of microRNA metabolism|inhibition of microRNA biosynthetic process|inhibition of microRNA biosynthesis|inhibition of production of microRNAs involved in gene silencing by microRNA|down-regulation of microRNA-mediated gene silencing, production of microRNAs|down regulation of production of microRNAs involved in gene silencing by microRNA|down-regulation of gene silencing by miRNA, production of miRNAs|down-regulation of production of microRNAs involved in gene silencing by microRNA|negative regulation of microRNA biogenesis|down regulation of miRNA biogenesis|downregulation of microRNA biosynthesis|down regulation of microRNA-mediated gene silencing, production of microRNAs|down-regulation of microRNA biosynthesis|negative regulation of miRNA biogenesis|down-regulation of miRNA biogenesis|downregulation of miRNA processing|down regulation of microRNA metabolism|inhibition of microRNA metabolism|downregulation of gene silencing by miRNA, production of miRNAs|down regulation of microRNA biogenesis|inhibition of microRNA-mediated gene silencing, production of microRNAs|downregulation of miRNA biogenesis|inhibition of microRNA biogenesis|down-regulation of microRNA biosynthetic process|inhibition of microRNA metabolic process|negative regulation of gene silencing by miRNA, production of miRNAs|negative regulation of microRNA-mediated gene silencing, production of microRNAs|negative regulation of microRNA biosynthetic process|down regulation of microRNA biosynthesis|down-regulation of microRNA biogenesis|inhibition of miRNA biogenesis|negative regulation of microRNA metabolic process|inhibition of miRNA processing|downregulation of microRNA metabolism|inhibition of gene silencing by miRNA, production of miRNAs|down-regulation of production of miRNAs involved in gene silencing by miRNA|down-regulation of miRNA-mediated gene silencing, production of miRNAs|negative regulation of miRNA processing|down regulation of production of miRNAs involved in gene silencing by miRNA|downregulation of production of miRNAs involved in gene silencing by miRNA|downregulation of miRNA-mediated gene silencing, production of miRNAs|down-regulation of microRNA metabolic process|down regulation of miRNA processing|down regulation of microRNA metabolic process|downregulation of microRNA-mediated gene silencing, production of microRNAs|down regulation of microRNA biosynthetic process						rph	2015-01-15T13:58:22Z						biological_process											owl:Class	
GO:0001961	biolink:NamedThing	positive regulation of cytokine-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.	got7fsn_ti	positive regulation of cytokine mediated signalling pathway|activation of cytokine mediated signaling pathway|positive regulation of cytokine and chemokine mediated signaling pathway|up-regulation of cytokine mediated signaling pathway|up regulation of cytokine mediated signaling pathway|stimulation of cytokine mediated signaling pathway|upregulation of cytokine mediated signaling pathway|positive regulation of cytokine mediated signaling pathway													biological_process											owl:Class	
GO:0052706	biolink:NamedThing	histidine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.	got7fsn_ti	S-adenosyl-L-methionine:L-histidine alpha-N-methyltransferase activity|S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase activity|histidine methyltransferase activity|histidine-alpha-N-methyltransferase activity						ai	2011-08-05T11:57:40Z						molecular_function											owl:Class	
GO:0060186	biolink:NamedThing	outer ear emergence	The growth of the outer ear.	got7fsn_ti	ear extroversion|ear elevation|outer ear growth													biological_process											owl:Class	
GO:0042473	biolink:NamedThing	outer ear morphogenesis	The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.	got7fsn_ti														biological_process											owl:Class	
GO:0009431	biolink:NamedThing	bacterial-type flagellum basal body, MS ring	One of the rings of the bacterial-type flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane.	got7fsn_ti	flagellar basal body, MS ring|flagellar basal body, mounting plate|flagellin-based flagellum basal body, MS ring										GO:0009430			cellular_component											owl:Class	
GO:0042721	biolink:NamedThing	TIM22 mitochondrial import inner membrane insertion complex	A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12.	got7fsn_ti	mitochondrial protein translocase complex|mitochondrial inner membrane protein insertion complex|Tim22 complex													cellular_component											owl:Class	
GO:0046403	biolink:NamedThing	polynucleotide 3'-phosphatase activity	Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.	got7fsn_ti	polynucleotide 3'-phosphohydrolase activity|5'-polynucleotidekinase 3'-phosphatase activity|2'(3')-polynucleotidase activity|DNA 3'-phosphatase activity|deoxyribonucleate 3'-phosphatase activity											Reactome:R-HSA-5649705|EC:3.1.3.32|MetaCyc:POLYNUCLEOTIDE-3-PHOSPHATASE-RXN|RHEA:14113		molecular_function											owl:Class	
GO:0098506	biolink:NamedThing	polynucleotide 3' dephosphorylation	The process of removing one or more phosphate groups from the 3' end of a polynucleotide.	got7fsn_ti														biological_process											owl:Class	
GO:0035221	biolink:NamedThing	genital disc pattern formation	The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.	got7fsn_ti														biological_process											owl:Class	
GO:0110038	biolink:NamedThing	negative regulation of nematode male tail tip morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.	got7fsn_ti							kmv	2017-07-24T20:29:00Z						biological_process											owl:Class	
GO:0004901	biolink:NamedThing	granulocyte macrophage colony-stimulating factor receptor activity	Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	granulocyte macrophage colony stimulating factor receptor activity|GMC-SF receptor activity|CSF-2 receptor activity|GM-CSF receptor activity|CSF2R										GO:0030525			molecular_function											owl:Class	
GO:0042021	biolink:NamedThing	granulocyte macrophage colony-stimulating factor complex binding	Binding to a granulocyte macrophage colony-stimulating factor complex.	got7fsn_ti	GMC-SF complex binding|GM-CSF complex binding|granulocyte macrophage colony stimulating factor complex binding													molecular_function											owl:Class	
GO:0072052	biolink:NamedThing	juxtaglomerulus cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-01-25T03:58:01Z						biological_process											owl:Class	
GO:0098031	biolink:NamedThing	icosahedral viral capsid, collar	A small disk located at the base of some icosahedral virus capsids.	got7fsn_ti							bm	2012-07-19T15:01:12Z						cellular_component											owl:Class	
GO:0031905	biolink:NamedThing	early endosome lumen	The volume enclosed by the membrane of an early endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0005769	biolink:NamedThing	early endosome	A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.	got7fsn_ti												NIF_Subcellular:nlx_subcell_20090701		cellular_component											owl:Class	
GO:0016465	biolink:NamedThing	chaperonin ATPase complex	Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.	got7fsn_ti														cellular_component											owl:Class	
GO:0051319	biolink:NamedThing	G2 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:G2_phase		biological_process											owl:Class	
GO:0072311	biolink:NamedThing	glomerular epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.	got7fsn_ti							mah	2010-04-09T06:49:21Z						biological_process											owl:Class	
GO:0071818	biolink:NamedThing	BAT3 complex	A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A.	got7fsn_ti	BAG6-UBL4A-TRC35 complex|Bag6 complex|BAT3-TRC35-UBL4A complex	https://github.com/geneontology/go-ontology/issues/20919					mah	2010-09-07T11:01:38Z						cellular_component											owl:Class	
GO:1903071	biolink:NamedThing	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.	got7fsn_ti	activation of ERAD|up regulation of ER-associated protein catabolic process|up-regulation of ER-associated protein breakdown|up regulation of endoplasmic reticulum-associated protein catabolism|up regulation of ER-associated protein degradation|positive regulation of ER-associated protein degradation|up-regulation of endoplasmic reticulum-associated protein catabolic process|activation of ER-associated protein catabolism|up-regulation of ER-associated protein catabolic process|up regulation of ER-associated protein catabolism|upregulation of ER-associated protein catabolism|activation of ER-associated protein breakdown|positive regulation of ERAD|upregulation of ER-associated protein catabolic process|upregulation of ERAD|positive regulation of ER-associated protein catabolism|activation of ER-associated protein catabolic process|up regulation of ER-associated ubiquitin-dependent protein catabolic process|activation of ER-associated ubiquitin-dependent protein catabolic process|upregulation of ER-associated protein degradation|activation of endoplasmic reticulum-associated protein catabolism|activation of ER-associated protein degradation|up regulation of ER-associated protein breakdown|activation of endoplasmic reticulum-associated protein catabolic process|up-regulation of endoplasmic reticulum-associated protein catabolism|up-regulation of ER-associated protein degradation|positive regulation of ER-associated protein catabolic process|positive regulation of endoplasmic reticulum-associated protein catabolism|up-regulation of ER-associated protein catabolism|up regulation of ERAD|upregulation of endoplasmic reticulum-associated protein catabolism|upregulation of ER-associated protein breakdown|up regulation of endoplasmic reticulum-associated protein catabolic process|upregulation of ER-associated ubiquitin-dependent protein catabolic process|upregulation of endoplasmic reticulum-associated protein catabolic process|positive regulation of endoplasmic reticulum-associated protein catabolic process|up-regulation of ER-associated ubiquitin-dependent protein catabolic process|positive regulation of ER-associated protein breakdown|up-regulation of ERAD						rph	2014-05-28T17:54:04Z						biological_process											owl:Class	
GO:0120118	biolink:NamedThing	flagella connector	A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum.	got7fsn_ti					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use.		krc	2017-12-11T22:24:17Z						cellular_component											owl:Class	
GO:0008316	biolink:NamedThing	structural constituent of vitelline membrane	The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster.	got7fsn_ti														molecular_function											owl:Class	
GO:0001401	biolink:NamedThing	SAM complex	A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.	got7fsn_ti	mitochondrial sorting and assembly machinery complex|TOB complex				See also the cellular component term 'mitochondrial outer membrane translocase complex ; GO:0005742'.									cellular_component											owl:Class	
GO:1903051	biolink:NamedThing	negative regulation of proteolysis involved in cellular protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.	got7fsn_ti	negative regulation of peptidolysis during cellular protein catabolic process|down regulation of peptidolysis during cellular protein catabolic process|downregulation of proteolysis involved in cellular protein catabolic process|down regulation of proteolysis during cellular protein catabolic process|negative regulation of proteolysis during cellular protein catabolic process|down regulation of peptidolysis during cellular protein catabolism|down-regulation of peptidolysis involved in cellular protein catabolic process|downregulation of peptidolysis during cellular protein catabolism|inhibition of peptidolysis involved in cellular protein catabolic process|inhibition of peptidolysis involved in cellular protein catabolism|negative regulation of peptidolysis during cellular protein catabolism|inhibition of peptidolysis during cellular protein catabolism|down-regulation of peptidolysis during cellular protein catabolic process|downregulation of peptidolysis involved in cellular protein catabolic process|down-regulation of proteolysis during cellular protein catabolic process|down regulation of peptidolysis involved in cellular protein catabolism|inhibition of proteolysis during cellular protein catabolism|down regulation of proteolysis during cellular protein catabolism|down regulation of peptidolysis involved in cellular protein catabolic process|down-regulation of proteolysis during cellular protein catabolism|inhibition of proteolysis involved in cellular protein catabolic process|down-regulation of peptidolysis involved in cellular protein catabolism|down-regulation of peptidolysis during cellular protein catabolism|negative regulation of peptidolysis involved in cellular protein catabolic process|negative regulation of peptidolysis involved in cellular protein catabolism|downregulation of peptidolysis during cellular protein catabolic process|down-regulation of proteolysis involved in cellular protein catabolic process|down regulation of proteolysis involved in cellular protein catabolic process|downregulation of proteolysis during cellular protein catabolic process|inhibition of peptidolysis during cellular protein catabolic process|inhibition of proteolysis during cellular protein catabolic process|negative regulation of proteolysis during cellular protein catabolism|downregulation of proteolysis during cellular protein catabolism|downregulation of peptidolysis involved in cellular protein catabolism				Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP).		rl	2014-05-22T18:00:51Z						biological_process											owl:Class	
GO:0097734	biolink:NamedThing	extracellular exosome biogenesis	The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.	got7fsn_ti	ILV assembly|exosome biogenesis|intraluminal vesicle assembly|exosome production|exosome assembly or secretion						pr	2016-10-03T14:35:25Z						biological_process											owl:Class	
GO:0097593	biolink:NamedThing	ventral disc microtubule array	A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane.	got7fsn_ti	ventral disk microtubule array|ventral disc spiral microtubule array|spiral microtubule array				Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:17:17Z						cellular_component											owl:Class	
GO:0140010	biolink:NamedThing	D-aspartate transmembrane transporter activity	Enables the transfer of D-aspartate from one side of a membrane to the other.	got7fsn_ti							pg	2017-03-13T11:15:15Z						molecular_function											owl:Class	
GO:0070777	biolink:NamedThing	D-aspartate transport	The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							mah	2009-07-02T01:42:57Z						biological_process											owl:Class	
GO:0015550	biolink:NamedThing	galacturonate transmembrane transporter activity	Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	got7fsn_ti														molecular_function											owl:Class	
GO:0015737	biolink:NamedThing	galacturonate transmembrane transport	The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	galacturonate transport													biological_process											owl:Class	
GO:0004961	biolink:NamedThing	thromboxane A2 receptor activity	Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein.	got7fsn_ti	TXA(2) receptor activity|TXA2 receptor activity													molecular_function											owl:Class	
GO:0038193	biolink:NamedThing	thromboxane A2 signaling pathway	The series of molecular signals generated as a consequence of thromboxane A2 binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	TXA2 signaling|TXA(2) receptor signaling						bf	2013-09-02T16:07:01Z						biological_process											owl:Class	
GO:1900747	biolink:NamedThing	negative regulation of vascular endothelial growth factor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway.	got7fsn_ti	negative regulation of VEGF-activated signaling pathway|down-regulation of VEGF signaling|down-regulation of VEGF-activated signaling pathway|downregulation of VEGF-activated signaling pathway|negative regulation of vascular endothelial growth factor signalling pathway|downregulation of vascular endothelial growth factor signalling pathway|negative regulation of VEGF signaling|down regulation of VEGF-activated signaling pathway|downregulation of vascular endothelial growth factor signaling pathway|down regulation of vascular endothelial growth factor signaling pathway|downregulation of VEGF signaling|inhibition of vascular endothelial growth factor signalling pathway|down regulation of vascular endothelial growth factor signalling pathway|inhibition of vascular endothelial growth factor signaling pathway|inhibition of VEGF-activated signaling pathway|down-regulation of vascular endothelial growth factor signaling pathway|down-regulation of vascular endothelial growth factor signalling pathway|inhibition of VEGF signaling|down regulation of VEGF signaling						pm	2012-05-29T08:28:29Z						biological_process											owl:Class	
GO:0050325	biolink:NamedThing	tauropine dehydrogenase activity	Catalysis of the reaction: H(2)O + NAD(+) + tauropine = H(+) + NADH + pyruvate + taurine.	got7fsn_ti	2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)|N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)											MetaCyc:TAUROPINE-DEHYDROGENASE-RXN|RHEA:12580|KEGG_REACTION:R01683|EC:1.5.1.23		molecular_function											owl:Class	
GO:0015167	biolink:NamedThing	arabitol transmembrane transporter activity	Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.	got7fsn_ti	arabinitol transporter activity													molecular_function											owl:Class	
GO:0015792	biolink:NamedThing	arabinitol transmembrane transport	The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.	got7fsn_ti	arabinitol transport|arabitol transport													biological_process											owl:Class	
GO:0055108	biolink:NamedThing	Golgi to transport vesicle transport	The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0015094	biolink:NamedThing	lead ion transmembrane transporter activity	Enables the transfer of lead (Pb) ions from one side of a membrane to the other.	got7fsn_ti	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity													molecular_function											owl:Class	
GO:0015692	biolink:NamedThing	lead ion transport	The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0097103	biolink:NamedThing	endothelial stalk cell fate specification	The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout.	got7fsn_ti	angiogenic stalk cell fate specification						pr	2011-07-27T10:32:38Z						biological_process											owl:Class	
GO:0002040	biolink:NamedThing	sprouting angiogenesis	The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.	got7fsn_ti														biological_process											owl:Class	
GO:0071130	biolink:NamedThing	alpha5-beta1 integrin-LPP3 complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3.	got7fsn_ti	ITGA5-ITGB1-PPAP2B complex						mah	2009-11-13T02:25:47Z						cellular_component											owl:Class	
GO:0015736	biolink:NamedThing	hexuronate transmembrane transport	The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.	got7fsn_ti	hexuronate transport													biological_process											owl:Class	
GO:0061927	biolink:NamedThing	TOC-TIC supercomplex I	The protein transport macromolecular complex of the chloroplast membrane that interacts with the precursor proteins and contains components of both the outer membrane and inner membrane complexes containing at least Toc75, Toc159, Toc34 and Tic110.	got7fsn_ti							dph	2017-08-28T13:18:20Z						cellular_component											owl:Class	
GO:0060932	biolink:NamedThing	His-Purkinje system cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.	got7fsn_ti							dph	2009-09-29T01:10:32Z						biological_process											owl:Class	
GO:0090351	biolink:NamedThing	seedling development	The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge.	got7fsn_ti							tb	2010-06-10T03:33:10Z				PO:0008037		biological_process											owl:Class	
GO:0009930	biolink:NamedThing	longitudinal side of cell surface	The side of the cell parallel to the zygotic axis.	got7fsn_ti														cellular_component											owl:Class	
GO:0061936	biolink:NamedThing	fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.	got7fsn_ti							dph	2017-09-05T18:43:24Z						biological_process											owl:Class	
GO:0099187	biolink:NamedThing	presynaptic cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.	got7fsn_ti							dos	2017-12-20T15:05:34Z						biological_process											owl:Class	
GO:0099172	biolink:NamedThing	presynapse organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.	got7fsn_ti	presynapse development|presynapse organisation|presynapse morphogenesis|presynapse organization and biogenesis													biological_process											owl:Class	
GO:0001891	biolink:NamedThing	phagocytic cup	An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0045756	biolink:NamedThing	positive regulation of initiation of acetate catabolic process by acetate	Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.	got7fsn_ti	up regulation of initiation of acetate catabolic process by acetate|activation of initiation of acetate catabolic process by acetate|stimulation of initiation of acetate catabolic process by acetate|positive regulation of initiation of acetate degradation by acetate|positive regulation of initiation of acetate breakdown by acetate|upregulation of initiation of acetate catabolic process by acetate|up-regulation of initiation of acetate catabolic process by acetate													biological_process											owl:Class	
GO:0072141	biolink:NamedThing	renal interstitial fibroblast development	The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure.	got7fsn_ti	kidney interstitial cell development						mah	2010-02-24T01:39:05Z						biological_process											owl:Class	
GO:0070927	biolink:NamedThing	negative regulation of ATP:ADP antiporter activity	Any process that stops or reduces the activity of an ATP:ADP antiporter.	got7fsn_ti	down-regulation of ATP:ADP antiporter activity|down regulation of ATP:ADP antiporter activity|inhibition of ATP:ADP antiporter activity|downregulation of ATP:ADP antiporter activity						mah	2009-09-16T02:58:02Z						biological_process											owl:Class	
GO:1990588	biolink:NamedThing	FtsBL complex	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB and FtsL.	got7fsn_ti	FtsB-FtsL complex				An example of this is FtsB in E. coli (P0A6S5) in PMID:15165235 (inferred from physical interaction).		bhm	2014-12-15T09:33:00Z						cellular_component											owl:Class	
GO:0070159	biolink:NamedThing	mitochondrial threonyl-tRNA aminoacylation	The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0019822	biolink:NamedThing	P4 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.	got7fsn_ti	peroxisome vesicle				Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'.									cellular_component											owl:Class	
GO:1990201	biolink:NamedThing	alkanesulfonate monooxygenase complex	A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer.	got7fsn_ti	SsuD complex						bhm	2013-10-03T14:55:08Z						cellular_component											owl:Class	
GO:1901234	biolink:NamedThing	positive regulation of convergent extension involved in axis elongation	Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation.	got7fsn_ti	up-regulation of convergent extension involved in axis elongation|upregulation of convergent extension involved in axis elongation|activation of convergent extension involved in axis elongation|up regulation of convergent extension involved in axis elongation						vk	2012-08-07T14:22:19Z						biological_process											owl:Class	
GO:0010353	biolink:NamedThing	response to trehalose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.	got7fsn_ti	response to trehalose stimulus													biological_process											owl:Class	
GO:0007375	biolink:NamedThing	anterior midgut invagination	Internalization of the anterior midgut into the interior of the embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0010004	biolink:NamedThing	gastrulation involving germ band extension	A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0034045	biolink:NamedThing	phagophore assembly site membrane	A cellular membrane associated with the phagophore assembly site.	got7fsn_ti	phagophore|PAS membrane|pre-autophagosomal structure membrane|isolation membrane													cellular_component											owl:Class	
GO:0098591	biolink:NamedThing	external side of apical plasma membrane	The leaflet the apical region of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	got7fsn_ti							dos	2014-03-06T12:04:33Z						cellular_component											owl:Class	
GO:0010006	biolink:NamedThing	Toc complex	Protein translocon complex at the chloroplast outer membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0042825	biolink:NamedThing	TAP complex	A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum.	got7fsn_ti	transporter associated with antigen presentation													cellular_component											owl:Class	
GO:0034306	biolink:NamedThing	regulation of sexual sporulation	Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.	got7fsn_ti	regulation of meiotic sporulation|regulation of meiotic spore formation|regulation of sexual spore formation|MAPKKK cascade during sporulation													biological_process											owl:Class	
GO:1990379	biolink:NamedThing	lipid transport across blood-brain barrier	The directed movement of lipid molecules passing through the blood-brain barrier.	got7fsn_ti	lipid transport across blood brain barrier						sjp	2014-05-08T09:52:28Z						biological_process											owl:Class	
GO:0009925	biolink:NamedThing	basal plasma membrane	The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.	got7fsn_ti														cellular_component											owl:Class	
GO:0019888	biolink:NamedThing	protein phosphatase regulator activity	Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.	got7fsn_ti	protein phosphatase type 1 regulator activity|protein phosphatase type 1, intrinsic regulator activity|protein phosphatase type 4 regulator activity|protein phosphatase 3 regulator activity|calcineurin regulator activity|protein phosphatase type 2A regulator activity|protein phosphatase type 2B, intrinsic regulator activity|protein phosphatase 3, intrinsic regulator activity|protein phosphatase type 4, intrinsic regulator activity|protein phosphatase type 2B regulator activity|calcineurin, intrinsic regulator activity|protein phosphatase 2 regulator activity|protein phosphatase 2, intrinsic regulator activity|protein phosphatase type 2A, intrinsic regulator activity										GO:0030359|GO:0008601|GO:0030362|GO:0008599	Reactome:R-HSA-180038		molecular_function											owl:Class	
GO:0031898	biolink:NamedThing	chromoplast envelope	The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	got7fsn_ti														cellular_component											owl:Class	
GO:0002336	biolink:NamedThing	B-1 B cell lineage commitment	The process in which an immature B cell becomes committed to become a B-1 B cell.	got7fsn_ti	B-1 B lymphocyte lineage commitment|B-1 B-cell lineage commitment|B-1 B-lymphocyte lineage commitment													biological_process											owl:Class	
GO:0001923	biolink:NamedThing	B-1 B cell differentiation	The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.	got7fsn_ti	B-1 B-cell differentiation|B-1 B cell development|B-1 B-lymphocyte differentiation|B-1 B lymphocyte differentiation													biological_process											owl:Class	
GO:0001874	biolink:NamedThing	(1->3)-beta-D-glucan immune receptor activity	Combining with (1->3)-beta-D-glucans to initiate an innate immune response.	got7fsn_ti	beta-1,3-D-glucan receptor activity|(1->3)-beta-D-glucan receptor activity|1,3-beta-D-glucan receptor activity|(1,3)-beta-D-glucan receptor activity|zymosan receptor activity													molecular_function											owl:Class	
GO:0001872	biolink:NamedThing	(1->3)-beta-D-glucan binding	Binding to a (1->3)-beta-D-glucan.	got7fsn_ti	1,3-beta-D-glucan binding|zymosan binding|callose binding										GO:0080087			molecular_function											owl:Class	
GO:0060534	biolink:NamedThing	trachea cartilage development	The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	got7fsn_ti							dph	2009-04-10T09:00:18Z						biological_process											owl:Class	
GO:0002180	biolink:NamedThing	5-lipoxygenase complex	An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.	got7fsn_ti							hjd	2011-06-09T01:05:53Z						cellular_component											owl:Class	
GO:0097234	biolink:NamedThing	epidermal lamellar body membrane	The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.	got7fsn_ti							pr	2012-01-26T10:32:13Z						cellular_component											owl:Class	
GO:0039012	biolink:NamedThing	pronephric sinus development	The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules.	got7fsn_ti							bf	2010-07-02T09:55:23Z						biological_process											owl:Class	
GO:0033693	biolink:NamedThing	neurofilament bundle assembly	The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.	got7fsn_ti	NF bundle assembly													biological_process											owl:Class	
GO:1990229	biolink:NamedThing	iron-sulfur cluster assembly complex	A protein complex capable of assembling an iron-sulfur (Fe-S) cluster.	got7fsn_ti	SufBCD complex|Fe-S cluster assembly complex						bhm	2013-11-12T09:15:03Z						cellular_component											owl:Class	
GO:1990182	biolink:NamedThing	exosomal secretion	The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.	got7fsn_ti	extracellular vesicular exosome secretion|exosomal protein secretion|exosomal secretory pathway|secretion of exosome|multi-vesicular body fusion with plasma membrane						hjd	2013-09-04T21:08:14Z						biological_process											owl:Class	
GO:0001701	biolink:NamedThing	in utero embryonic development	The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.	got7fsn_ti														biological_process											owl:Class	
GO:0061330	biolink:NamedThing	Malpighian tubule stellate cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.	got7fsn_ti							dph	2010-09-28T01:32:55Z						biological_process											owl:Class	
GO:1990788	biolink:NamedThing	GLI-SUFU complex	A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins.	got7fsn_ti					An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay).		bhm	2015-06-26T13:49:47Z						cellular_component											owl:Class	
GO:0000345	biolink:NamedThing	cytosolic DNA-directed RNA polymerase complex	The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity.	got7fsn_ti														cellular_component											owl:Class	
GO:0003416	biolink:NamedThing	endochondral bone growth	The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.	got7fsn_ti							dph	2009-12-22T08:52:55Z						biological_process											owl:Class	
GO:0005006	biolink:NamedThing	epidermal growth factor-activated receptor activity	Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	transforming growth factor-alpha receptor activity|epidermal growth factor receptor activity|EGFR|TGF-alpha receptor activity|EGF receptor activity				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand EGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.						GO:0005023			molecular_function											owl:Class	
GO:0039005	biolink:NamedThing	specification of pronephric tubule identity	The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.	got7fsn_ti							bf	2010-07-02T09:33:56Z						biological_process											owl:Class	
GO:0020038	biolink:NamedThing	subpellicular network	A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton.	got7fsn_ti														cellular_component											owl:Class	
GO:0060185	biolink:NamedThing	outer ear unfolding	The opening and spreading out of the outer ear.	got7fsn_ti														biological_process											owl:Class	
GO:0071562	biolink:NamedThing	nucleus-vacuole junction assembly	The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction, which are membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.	got7fsn_ti	NVJ formation|NV junction formation|NVJ assembly|NV junction assembly|nucleus-vacuole junction formation						mah	2010-01-20T02:16:36Z						biological_process											owl:Class	
GO:1900161	biolink:NamedThing	regulation of phospholipid scramblase activity	Any process that modulates the frequency, rate or extent of phospholipid scramblase activity.	got7fsn_ti							rph	2012-03-08T10:57:19Z						biological_process											owl:Class	
GO:0061835	biolink:NamedThing	ventral surface of cell	The surface of a migrating cell that is in contact with the substratum or cell layer.	got7fsn_ti														cellular_component											owl:Class	
GO:0021687	biolink:NamedThing	cerebellar molecular layer morphogenesis	The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	got7fsn_ti														biological_process											owl:Class	
GO:0071089	biolink:NamedThing	alphaV-beta3 integrin-tissue transglutaminase complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.	got7fsn_ti	ITGAV-ITGB3-TGM2 complex						mah	2009-11-06T04:46:02Z						cellular_component											owl:Class	
GO:0038101	biolink:NamedThing	sequestering of nodal from receptor via nodal binding	Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.	got7fsn_ti	extracellular regulation of nodal|nodal antagonist activity|binding to and sequestering nodal						bf	2012-02-17T11:21:22Z						biological_process											owl:Class	
GO:1900108	biolink:NamedThing	negative regulation of nodal signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway.	got7fsn_ti	down regulation of nodal signaling pathway|down regulation of nodal signaling|negative regulation of nodal signalling pathway|downregulation of nodal signaling|down-regulation of nodal signaling pathway|inhibition of nodal signaling|downregulation of nodal signaling pathway|negative regulation of nodal signaling|down-regulation of nodal signaling|inhibition of nodal signaling pathway						bf	2012-02-16T03:34:23Z						biological_process											owl:Class	
GO:0072175	biolink:NamedThing	epithelial tube formation	The developmental process pertaining to the initial formation of an epithelial tube.	got7fsn_ti							mah	2010-02-26T02:15:40Z						biological_process											owl:Class	
GO:0070929	biolink:NamedThing	trans-translation	A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.	got7fsn_ti							mah	2009-09-16T04:06:12Z						biological_process											owl:Class	
GO:0097539	biolink:NamedThing	ciliary transition fiber	A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium).	got7fsn_ti	distal appendage of centriole|transition fibre|cilial transition fiber|cilial transition fibre|cilium transition fibre|transition fiber|centriolar distal appendage|distal appendage of basal body|ciliary transition fibre|cilium transition fiber|distal appendage of mother centriole				In mammals, ciliary transition fibers comprise at least five components (Ccdc41/Cep83, Cep89/Cep123, Sclt1, Fbf1, and Cep164) (PMID:24469809).		pr	2013-12-03T16:46:37Z						cellular_component											owl:Class	
GO:0042704	biolink:NamedThing	uterine wall breakdown	The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels.	got7fsn_ti														biological_process											owl:Class	
GO:0042703	biolink:NamedThing	menstruation	The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Menstruation		biological_process											owl:Class	
GO:0002114	biolink:NamedThing	interleukin-33 receptor activity	Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-33 receptor activity|IL-33R													molecular_function											owl:Class	
GO:0002113	biolink:NamedThing	interleukin-33 binding	Binding to interleukin-33.	got7fsn_ti	IL-33 binding													molecular_function											owl:Class	
GO:0002801	biolink:NamedThing	negative regulation of antifungal peptide secretion	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion.	got7fsn_ti	inhibition of antifungal peptide secretion|downregulation of antifungal peptide secretion|down-regulation of antifungal peptide secretion|down regulation of antifungal peptide secretion													biological_process											owl:Class	
GO:0048900	biolink:NamedThing	anterior lateral line neuromast primordium migration	The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.	got7fsn_ti	ALL neuromast primordium migration													biological_process											owl:Class	
GO:0048899	biolink:NamedThing	anterior lateral line development	The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.	got7fsn_ti	anterior LL development													biological_process											owl:Class	
GO:0060913	biolink:NamedThing	cardiac cell fate determination	The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	got7fsn_ti	cardiocyte cell fate determination						dph	2009-09-17T08:55:29Z						biological_process											owl:Class	
GO:0044091	biolink:NamedThing	membrane biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0086024	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate	An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate.	got7fsn_ti	adrenergic receptor signalling pathway involved in positive regulation of heart rate|activation of funny current by beta-adrenergic receptor signaling pathway|beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|adrenergic receptor signaling pathway involved in positive regulation of heart rate|Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|If activation by beta-adrenergic receptor signaling pathway|adenylate cyclase-activating cardiac adrenergic receptor signaling pathway						tb	2011-11-10T09:38:49Z						biological_process											owl:Class	
GO:0086010	biolink:NamedThing	membrane depolarization during action potential	The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti							tb	2011-11-10T08:15:05Z						biological_process											owl:Class	
GO:0090331	biolink:NamedThing	negative regulation of platelet aggregation	Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.	got7fsn_ti	platelet disaggregation						tb	2010-05-14T10:46:08Z						biological_process											owl:Class	
GO:0030073	biolink:NamedThing	insulin secretion	The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045												biological_process											owl:Class	
GO:0007426	biolink:NamedThing	tracheal outgrowth, open tracheal system	The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0099527	biolink:NamedThing	postsynapse to nucleus signaling pathway	A series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).	got7fsn_ti	postsynaptic signaling to nucleus													biological_process											owl:Class	
GO:1903751	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.	got7fsn_ti	downregulation of H2O2-induced intrinsic apoptotic signaling pathway|inhibition of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down-regulation of intrinsic apoptotic signaling pathway in response to H2O2|inhibition of intrinsic apoptotic signaling pathway in response to H2O2|downregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|negative regulation of H2O2-induced intrinsic apoptotic signaling pathway|down regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|downregulation of intrinsic apoptotic signaling pathway in response to H2O2|down regulation of H2O2-induced intrinsic apoptotic signaling pathway|inhibition of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|down regulation of intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|down-regulation of H2O2-induced intrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway in response to H2O2|inhibition of H2O2-induced intrinsic apoptotic signaling pathway|downregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway						krc	2014-12-12T23:04:37Z						biological_process											owl:Class	
GO:0072274	biolink:NamedThing	metanephric glomerular basement membrane development	The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.	got7fsn_ti							mah	2010-04-01T02:43:51Z						biological_process											owl:Class	
GO:0046597	biolink:NamedThing	negative regulation of viral entry into host cell	Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell.	got7fsn_ti	negative regulation of viral penetration into host cell													biological_process											owl:Class	
GO:0035992	biolink:NamedThing	tendon formation	The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.	got7fsn_ti							bf	2011-08-30T01:35:10Z						biological_process											owl:Class	
GO:0050764	biolink:NamedThing	regulation of phagocytosis	Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.	got7fsn_ti														biological_process											owl:Class	
GO:0044223	biolink:NamedThing	pirellulosome	A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm.	got7fsn_ti							jl	2009-11-12T04:08:07Z						cellular_component											owl:Class	
GO:0086036	biolink:NamedThing	regulation of cardiac muscle cell membrane potential	Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	got7fsn_ti							tb	2011-11-11T03:23:36Z						biological_process											owl:Class	
GO:0007405	biolink:NamedThing	neuroblast proliferation	The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.	got7fsn_ti											GO:0043349|GO:0043350			biological_process											owl:Class	
GO:0071281	biolink:NamedThing	cellular response to iron ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.	got7fsn_ti	cellular response to iron						mah	2009-12-10T03:57:22Z						biological_process											owl:Class	
GO:0050577	biolink:NamedThing	GDP-L-fucose synthase activity	Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.	got7fsn_ti	GDP-fucose synthetase activity|GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase activity|GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)											Reactome:R-HSA-6787642|MetaCyc:1.1.1.271-RXN|RHEA:18885|EC:1.1.1.271		molecular_function											owl:Class	
GO:2001284	biolink:NamedThing	regulation of BMP secretion	Any process that modulates the frequency, rate or extent of BMP secretion.	got7fsn_ti	regulation of BMP protein secretion|regulation of bone morphogenetic protein secretion						bf	2011-12-15T02:15:28Z						biological_process											owl:Class	
GO:0032203	biolink:NamedThing	telomere formation via telomerase	A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.	got7fsn_ti														biological_process											owl:Class	
GO:1905324	biolink:NamedThing	telomere-telomerase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex.	got7fsn_ti	telomere-telomerase complex formation						mah	2016-07-18T10:38:22Z						biological_process											owl:Class	
GO:0061349	biolink:NamedThing	planar cell polarity pathway involved in cardiac right atrium morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.	got7fsn_ti							dph	2010-10-01T10:52:01Z						biological_process											owl:Class	
GO:0003213	biolink:NamedThing	cardiac right atrium morphogenesis	The process in which the right cardiac atrium is generated and organized.	got7fsn_ti							dph	2009-10-13T09:49:03Z						biological_process											owl:Class	
GO:0072226	biolink:NamedThing	metanephric long descending thin limb bend development	The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.	got7fsn_ti							mah	2010-03-18T03:37:16Z						biological_process											owl:Class	
GO:0019823	biolink:NamedThing	P5 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.	got7fsn_ti	peroxisome vesicle				Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', and 'P6 peroxisome ; GO:0019824'.									cellular_component											owl:Class	
GO:0043674	biolink:NamedThing	columella	A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella).	got7fsn_ti	sexine 1													cellular_component											owl:Class	
GO:0035195	biolink:NamedThing	gene silencing by miRNA	Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA.	got7fsn_ti	gene silencing by microRNA|miRNA-mediated gene silencing|microRNA-mediated gene silencing													biological_process											owl:Class	
GO:0021763	biolink:NamedThing	subthalamic nucleus development	The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.	got7fsn_ti	corpus luysi development													biological_process											owl:Class	
GO:0021539	biolink:NamedThing	subthalamus development	The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.	got7fsn_ti	ventral thalamus development													biological_process											owl:Class	
GO:2000809	biolink:NamedThing	positive regulation of synaptic vesicle clustering	Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering.	got7fsn_ti							pr	2011-07-06T09:50:37Z						biological_process											owl:Class	
GO:0002493	biolink:NamedThing	lipid antigen assembly with MHC class Ib protein complex	The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.	got7fsn_ti														biological_process											owl:Class	
GO:0080110	biolink:NamedThing	sporopollenin biosynthetic process	The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.	got7fsn_ti	sporopollenin biosynthesis						dhl	2009-04-23T04:44:16Z						biological_process											owl:Class	
GO:1900277	biolink:NamedThing	negative regulation of proteinase activated receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity.	got7fsn_ti	down regulation of proteinase activated receptor activity|downregulation of proteinase activated receptor activity|inhibition of proteinase activated receptor activity|down-regulation of proteinase activated receptor activity						rl	2012-04-04T01:31:29Z						biological_process											owl:Class	
GO:0003422	biolink:NamedThing	growth plate cartilage morphogenesis	The process in which the anatomical structures of growth plate cartilage are generated and organized.	got7fsn_ti							dph	2009-12-22T09:21:30Z						biological_process											owl:Class	
GO:0034101	biolink:NamedThing	erythrocyte homeostasis	Any process of regulating the production and elimination of erythrocytes within an organism.	got7fsn_ti	RBC homeostasis|red blood cell homeostasis													biological_process											owl:Class	
GO:0080128	biolink:NamedThing	anther septum development	The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone.	got7fsn_ti							dhl	2009-04-28T04:41:16Z						biological_process											owl:Class	
GO:0042957	biolink:NamedThing	dextrin transmembrane transporter activity	Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042955	biolink:NamedThing	dextrin transport	The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0061090	biolink:NamedThing	positive regulation of sequestering of zinc ion	Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.	got7fsn_ti							dph	2010-04-26T01:38:53Z						biological_process											owl:Class	
GO:0033232	biolink:NamedThing	ABC-type D-methionine transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).	got7fsn_ti	ATPase-coupled D-methionine transporter activity|ATP-dependent methionine transmembrane transporter activity|D-methionine transmembrane transporter activity|ATPase-coupled methionine transmembrane transporter activity|D-methionine importer|methionine transmembrane-transporting ATPase activity|D-methionine exporter|D-methionine-exporting ATPase activity|D-methionine-importing ATPase activity|D-methionine-transporting ATPase activity|ATP-dependent D-methionine transporter activity|D-methionine transporter activity						jl	2012-08-07T15:59:50Z			GO:1901243|GO:0032521|GO:0032522|GO:0048474	EC:7.4.2.11|RHEA:29779		molecular_function											owl:Class	
GO:0048473	biolink:NamedThing	D-methionine transport	The directed movement of D-methionine into, out of, within, or between cells.	got7fsn_ti														biological_process											owl:Class	
GO:0061669	biolink:NamedThing	spontaneous neurotransmitter secretion	Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential.	got7fsn_ti	stimulus-independent neurotransmitter secretion						dph	2014-11-17T07:52:35Z						biological_process											owl:Class	
GO:0048213	biolink:NamedThing	Golgi vesicle prefusion complex stabilization	The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized.	got7fsn_ti	Golgi-derived vesicle prefusion complex stabilization|Golgi vesicle prefusion complex assembly|dictyosome vesicle prefusion complex stabilisation													biological_process											owl:Class	
GO:0097398	biolink:NamedThing	cellular response to interleukin-17	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.	got7fsn_ti	cellular response to IL-17						pr	2012-10-23T13:25:43Z						biological_process											owl:Class	
GO:0099560	biolink:NamedThing	synaptic membrane adhesion	The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.	got7fsn_ti	synapse adhesion between pre- and post-synapse													biological_process											owl:Class	
GO:0048852	biolink:NamedThing	diencephalon morphogenesis	The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0048853	biolink:NamedThing	forebrain morphogenesis	The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).	got7fsn_ti	prosencephalon morphogenesis													biological_process											owl:Class	
GO:0035493	biolink:NamedThing	SNARE complex assembly	The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	got7fsn_ti							bf	2010-04-26T02:50:52Z						biological_process											owl:Class	
GO:0001963	biolink:NamedThing	synaptic transmission, dopaminergic	The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	got7fsn_ti	dopaminergic synaptic transmission													biological_process											owl:Class	
CL:0000700	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006144	biolink:NamedThing	purine nucleobase metabolic process	The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.	got7fsn_ti	purine metabolism|purine base metabolism|purine metabolic process|purine base metabolic process													biological_process											owl:Class	
GO:0043999	biolink:NamedThing	histone acetyltransferase activity (H2A-K5 specific)	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5).	got7fsn_ti	histone lysine N-acetyltransferase activity (H2A-K5 specific)													molecular_function											owl:Class	
GO:0043977	biolink:NamedThing	histone H2A-K5 acetylation	The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone.	got7fsn_ti	histone H2A acetylation at K5													biological_process											owl:Class	
GO:0007493	biolink:NamedThing	endodermal cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	endoderm cell fate determination				Note that this term was 'endoderm determination'. Changed string to make it more consistent with parent term 'cell fate determination'.									biological_process											owl:Class	
GO:0043508	biolink:NamedThing	negative regulation of JUN kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.	got7fsn_ti	negative regulation of JUNK activity|downregulation of JNK activity|down regulation of JNK activity|down-regulation of JNK activity|inhibition of JNK activity													biological_process											owl:Class	
GO:0007254	biolink:NamedThing	JNK cascade	An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.	got7fsn_ti	MAPK9 cascade|JNK1 cascade|MAPK10 cascade|MAPK8 cascade|stress-activated protein kinase cascade|JNK2 cascade|SAPK cascade|JNK3 cascade|c-Jun N-terminal kinase cascade													biological_process											owl:Class	
GO:0048821	biolink:NamedThing	erythrocyte development	The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.	got7fsn_ti	RBC development|red blood cell development													biological_process											owl:Class	
GO:0010016	biolink:NamedThing	shoot system morphogenesis	The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground.	got7fsn_ti	shoot morphogenesis													biological_process											owl:Class	
GO:0012508	biolink:NamedThing	Golgi to ER transport vesicle membrane	The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER.	got7fsn_ti	Golgi-ER transport vesicle membrane|Golgi to endoplasmic reticulum transport vesicle membrane|Golgi to ER constitutive secretory pathway transport vesicle membrane|Golgi-endoplasmic reticulum transport vesicle membrane													cellular_component											owl:Class	
GO:2001208	biolink:NamedThing	negative regulation of transcription elongation by RNA polymerase I	Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I.	got7fsn_ti	negative regulation of transcription elongation from RNA polymerase I promoter|negative regulation of RNA elongation from Pol I promoter						se	2011-11-11T10:46:36Z						biological_process											owl:Class	
GO:1904341	biolink:NamedThing	regulation of colon smooth muscle contraction	Any process that modulates the frequency, rate or extent of colon smooth muscle contraction.	got7fsn_ti							sl	2015-06-11T21:16:58Z						biological_process											owl:Class	
GO:0021598	biolink:NamedThing	abducens nerve morphogenesis	The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	got7fsn_ti	CN VI development													biological_process											owl:Class	
GO:0044603	biolink:NamedThing	protein adenylylhydrolase activity	Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins.	got7fsn_ti	protein deAMPylation activity|protein deAMPylase activity						jl	2012-05-01T04:18:07Z						molecular_function											owl:Class	
GO:0030906	biolink:NamedThing	retromer, cargo-selective complex	The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.	got7fsn_ti	retromer, cargo recognition complex|cargo-selective retromer subcomplex|retromer, CRC|retromer CSC|retromer complex, inner shell													cellular_component											owl:Class	
GO:0015485	biolink:NamedThing	cholesterol binding	Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti														molecular_function											owl:Class	
GO:0061325	biolink:NamedThing	cell proliferation involved in outflow tract morphogenesis	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.	got7fsn_ti							dph	2010-09-28T09:29:30Z						biological_process											owl:Class	
GO:0070892	biolink:NamedThing	lipoteichoic acid immune receptor activity	Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response.	got7fsn_ti	lipoteichoic acid receptor activity						mah	2009-09-01T02:59:24Z						molecular_function											owl:Class	
GO:0070891	biolink:NamedThing	lipoteichoic acid binding	Binding to lipoteichoic acid.	got7fsn_ti							mah	2009-09-01T02:56:36Z						molecular_function											owl:Class	
GO:0072039	biolink:NamedThing	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.	got7fsn_ti	regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis						mah	2010-01-25T03:08:34Z						biological_process											owl:Class	
GO:0016593	biolink:NamedThing	Cdc73/Paf1 complex	A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.	got7fsn_ti	Paf1 complex|Paf1p complex													cellular_component											owl:Class	
GO:0032339	biolink:NamedThing	negative regulation of inhibin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.	got7fsn_ti	down regulation of inhibin secretion|downregulation of inhibin secretion|inhibition of inhibin secretion|down-regulation of inhibin secretion													biological_process											owl:Class	
GO:0030490	biolink:NamedThing	maturation of SSU-rRNA	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.	got7fsn_ti	processing of 20S pre-rRNA|SSU-rRNA maturation													biological_process											owl:Class	
GO:0005344	biolink:NamedThing	oxygen carrier activity	Binding to oxygen and delivering it to an acceptor molecule or a specific location.	got7fsn_ti	oxygen-carrying|hemocyanin|hemerythrin|globin	https://github.com/geneontology/go-ontology/issues/17399									GO:0015033			molecular_function											owl:Class	
GO:0015671	biolink:NamedThing	oxygen transport	The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0048826	biolink:NamedThing	cotyledon morphogenesis	The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.	got7fsn_ti														biological_process											owl:Class	
GO:0048825	biolink:NamedThing	cotyledon development	The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.	got7fsn_ti														biological_process											owl:Class	
GO:0021897	biolink:NamedThing	forebrain astrocyte development	The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.	got7fsn_ti														biological_process											owl:Class	
GO:0001744	biolink:NamedThing	insect visual primordium formation	Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.	got7fsn_ti	optic lobe and Bolwig's organ precursor formation|optic lobe placode formation										GO:0007457			biological_process											owl:Class	
GO:0001748	biolink:NamedThing	insect visual primordium development	The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	optic lobe and Bolwig's organ precursor development|optic lobe placode development|optic placode development										GO:0048049			biological_process											owl:Class	
GO:0009034	biolink:NamedThing	tryptophanase activity	Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate.	got7fsn_ti	tryptophan catabolism, using tryptophanase|L-tryptophan indole-lyase (deaminating) activity|tryptophan catabolic process, using tryptophanase|TNase activity|L-tryptophanase activity|L-tryptophan indole-lyase activity|L-tryptophan indole-lyase (deaminating; pyruvate forming) activity				Note that this term has a MetaCyc pathway reference as the pathway only has a single step.							RHEA:19553|MetaCyc:TRYPDEG-PWY|MetaCyc:TRYPTOPHAN-RXN|EC:4.1.99.1|KEGG_REACTION:R00673|UniPathway:UPA00332		molecular_function											owl:Class	
GO:0006569	biolink:NamedThing	tryptophan catabolic process	The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.	got7fsn_ti	tryptophan catabolic process, using tryptophanase|tryptophan catabolism|tryptophan degradation|tryptophan breakdown|tryptophan catabolism, using tryptophanase													biological_process											owl:Class	
GO:0035722	biolink:NamedThing	interleukin-12-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-12-mediated signaling pathway|interleukin-12-mediated signalling pathway						bf	2011-03-07T11:27:58Z						biological_process											owl:Class	
GO:1990659	biolink:NamedThing	sequestering of manganese ion	The process of binding or confining manganese ions such that they are separated from other components of a biological system.	got7fsn_ti	manganese ion sequestering|manganese ion retention|storage of manganese ion|manganese ion storage|manganese ion sequestration|retention of manganese ion|sequestration of manganese ion				An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T11:41:12Z						biological_process											owl:Class	
GO:0072580	biolink:NamedThing	bacterial-type EF-P lysine modification	The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).	got7fsn_ti	EF-P modification pathway				The EF-P modification pathway is now thought to be composed of three steps: conversion of alpha-lysyl-EF-P to beta-lysyl-EF-P, lysylation of Lys34, and hydroxylation of Lys34.		mah	2011-02-07T11:47:33Z						biological_process											owl:Class	
GO:1900438	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.	got7fsn_ti	inhibition of filamentous growth of a population of unicellular organisms in response to chemical stimulus|downregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|down regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|down-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus						di	2012-04-25T05:55:26Z						biological_process											owl:Class	
GO:1901076	biolink:NamedThing	positive regulation of engulfment of apoptotic cell	Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell.	got7fsn_ti	up-regulation of engulfment of apoptotic cell corpse|up-regulation of engulfment of cell corpse|activation of engulfment of apoptotic cell corpse|upregulation of engulfment of cell corpse|activation of engulfment of cell corpse|activation of engulfment of apoptotic cell|upregulation of engulfment of apoptotic cell corpse|up-regulation of engulfment of apoptotic cell|up regulation of engulfment of apoptotic cell corpse|up regulation of engulfment of apoptotic cell|positive regulation of engulfment of cell corpse|positive regulation of engulfment of apoptotic cell corpse|upregulation of engulfment of apoptotic cell|up regulation of engulfment of cell corpse						kmv	2012-07-02T07:32:51Z						biological_process											owl:Class	
GO:0043277	biolink:NamedThing	apoptotic cell clearance	The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.	got7fsn_ti	programmed cell clearance|apoptotic cell removal|efferocytosis				Note that unlike mammals or Drosophila, C. elegans (and many lower organisms) do not have professional macrophages/phagocytes, instead cell corpses are engulfed by neighboring cells. Cell types that can function as engulfing cells include hypodermal cells, gonadal sheath cells, pharyngeal muscle cells, and intestinal cells.									biological_process											owl:Class	
GO:0030938	biolink:NamedThing	collagen type XVIII trimer	A collagen homotrimer of alpha1(XVIII) chains.	got7fsn_ti														cellular_component											owl:Class	
GO:0055104	biolink:NamedThing	ligase inhibitor activity	Binds to and stops, prevents or reduces the activity of a ligase.	got7fsn_ti														molecular_function											owl:Class	
GO:1905520	biolink:NamedThing	positive regulation of presynaptic active zone assembly	Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.	got7fsn_ti	upregulation of presynaptic active zone assembly|up regulation of pre-synaptic active zone assembly|positive regulation of pre-synaptic active zone formation|positive regulation of presynaptic active zone formation|positive regulation of pre-synaptic active zone assembly|up-regulation of pre-synaptic active zone assembly|activation of pre-synaptic active zone component assembly|upregulation of pre-synaptic active zone formation|up-regulation of pre-synaptic active zone component assembly|up-regulation of presynaptic active zone assembly|positive regulation of pre-synaptic active zone component assembly|up-regulation of pre-synaptic active zone formation|up regulation of pre-synaptic active zone component formation|activation of pre-synaptic active zone assembly|up regulation of pre-synaptic active zone component assembly|up-regulation of pre-synaptic active zone component formation|upregulation of pre-synaptic active zone assembly|upregulation of pre-synaptic active zone component assembly|activation of pre-synaptic active zone component formation|up-regulation of presynaptic active zone formation|up regulation of presynaptic active zone assembly|up regulation of pre-synaptic active zone formation|upregulation of presynaptic active zone formation|up regulation of presynaptic active zone formation|upregulation of pre-synaptic active zone component formation|activation of presynaptic active zone formation|activation of pre-synaptic active zone formation|positive regulation of pre-synaptic active zone component formation|activation of presynaptic active zone assembly						rl	2016-10-01T09:38:07Z						biological_process											owl:Class	
GO:0016503	biolink:NamedThing	pheromone receptor activity	Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior.	got7fsn_ti														molecular_function											owl:Class	
GO:0019912	biolink:NamedThing	cyclin-dependent protein kinase activating kinase activity	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).	got7fsn_ti	CAK|cdk-activating kinase activity|cyclin-dependent protein kinase activating kinase, intrinsic catalyst activity										GO:0019913			molecular_function											owl:Class	
GO:0035919	biolink:NamedThing	negative regulation of low voltage-gated calcium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.	got7fsn_ti	down-regulation of low voltage-gated calcium channel activity in other organism|inhibition of low voltage-gated calcium channel activity in other organism|negative regulation of low voltage gated calcium channel activity in other organism|downregulation of low voltage-gated calcium channel activity in other organism|negative regulation of low voltage-dependent calcium channel activity in other organism						bf	2011-07-01T11:56:21Z						biological_process											owl:Class	
GO:0001649	biolink:NamedThing	osteoblast differentiation	The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.	got7fsn_ti	osteoblast cell differentiation													biological_process											owl:Class	
GO:1905137	biolink:NamedThing	regulation of viral DNA genome packaging via site-specific sequence recognition	Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.	got7fsn_ti							pr	2016-04-13T11:37:13Z						biological_process											owl:Class	
GO:0003391	biolink:NamedThing	amphid sensory organ dendrite retrograde extension	The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.	got7fsn_ti							dph	2009-12-09T09:28:27Z						biological_process											owl:Class	
GO:0070309	biolink:NamedThing	lens fiber cell morphogenesis	The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.	got7fsn_ti	lens fiber cell morphogenesis during differentiation|elongation of lens fiber cell|lens fibre cell morphogenesis													biological_process											owl:Class	
GO:0070307	biolink:NamedThing	lens fiber cell development	The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.	got7fsn_ti	lens fibre cell development													biological_process											owl:Class	
GO:0043559	biolink:NamedThing	insulin binding	Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	got7fsn_ti														molecular_function											owl:Class	
GO:0043710	biolink:NamedThing	cell adhesion involved in multi-species biofilm formation	The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species.	got7fsn_ti	cell adhesion during multi-species biofilm formation													biological_process											owl:Class	
GO:0044399	biolink:NamedThing	multi-species biofilm formation	A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	got7fsn_ti	multi-species surface biofilm formation|multi-species biofilm formation in or on host organism|multi-species biofilm formation on inanimate substrate|multi-species submerged biofilm formation										GO:0044401|GO:0090608|GO:0090607|GO:0044400			biological_process											owl:Class	
GO:0048914	biolink:NamedThing	myelination of anterior lateral line nerve axons	The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0048940	biolink:NamedThing	anterior lateral line nerve glial cell morphogenesis involved in differentiation	The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0051474	biolink:NamedThing	glucosylglycerol transmembrane transporter activity	Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.	got7fsn_ti														molecular_function											owl:Class	
GO:0051475	biolink:NamedThing	glucosylglycerol transport	The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0060335	biolink:NamedThing	positive regulation of interferon-gamma-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.	got7fsn_ti	positive regulation of interferon-gamma-mediated signalling pathway|positive regulation of gamma-interferon-mediated signaling pathway|positive regulation of type II IFN-mediated pathway|positive regulation of type II interferon-mediated signaling pathway|positive regulation of immune interferon-mediated signaling pathway													biological_process											owl:Class	
GO:0034341	biolink:NamedThing	response to interferon-gamma	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.	got7fsn_ti	response to type II IFN|response to immune interferon|response to type II interferon|response to gamma-interferon													biological_process											owl:Class	
GO:0097445	biolink:NamedThing	presynaptic active zone dense projection	Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered.	got7fsn_ti	active zone dense projection|pre-synaptic active zone dense projection						pr	2012-12-06T14:08:21Z				NIF_Subcellular:sao494258938		cellular_component											owl:Class	
GO:0020018	biolink:NamedThing	ciliary pocket membrane	That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket).	got7fsn_ti	cilium pocket membrane|flagellar pocket membrane|cilial pocket membrane				Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is mostly 'flagellar', but the primary term name reflects the cilium parentage.									cellular_component											owl:Class	
GO:0020016	biolink:NamedThing	ciliary pocket	Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes.	got7fsn_ti	cilial pocket|flagellar pocket|cilium pocket				Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is mostly 'flagellar', but the primary term name reflects the cilium parentage.									cellular_component											owl:Class	
GO:0009574	biolink:NamedThing	preprophase band	A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs.	got7fsn_ti												Wikipedia:Preprophase_band		cellular_component											owl:Class	
GO:0030486	biolink:NamedThing	smooth muscle dense body	Electron-dense region associated with a smooth muscle contractile fiber.	got7fsn_ti														cellular_component											owl:Class	
GO:0030485	biolink:NamedThing	smooth muscle contractile fiber	The contractile fiber of smooth muscle cells.	got7fsn_ti														cellular_component											owl:Class	
GO:0061989	biolink:NamedThing	sperm karyosome formation	The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome.	got7fsn_ti							dph	2018-02-15T21:29:47Z						biological_process											owl:Class	
GO:1903668	biolink:NamedThing	negative regulation of chemorepellent activity	Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity.	got7fsn_ti	inhibition of chemorepellent activity|negative regulation of chemorepellant activity|down regulation of chemorepellant activity|down-regulation of chemorepellent activity|down-regulation of chemorepellant activity|inhibition of chemorepellant activity|downregulation of chemorepellent activity|downregulation of chemorepellant activity|down regulation of chemorepellent activity						pf	2014-11-26T23:58:42Z						biological_process											owl:Class	
GO:0045479	biolink:NamedThing	vesicle targeting to fusome	The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome.	got7fsn_ti	vesicle-fusome targeting													biological_process											owl:Class	
GO:0061537	biolink:NamedThing	glycine secretion, neurotransmission	The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-21T16:19:02Z						biological_process											owl:Class	
GO:0080156	biolink:NamedThing	mitochondrial mRNA modification	The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti	mitochondrial mRNA editing|mitochondrial RNA editing						dhl	2010-09-01T03:55:48Z						biological_process											owl:Class	
GO:1990162	biolink:NamedThing	histone deacetylase activity (H3-K4 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.	got7fsn_ti							pr	2013-08-06T08:48:44Z						molecular_function											owl:Class	
GO:1990596	biolink:NamedThing	histone H3-K4 deacetylation	The modification of histone H3 by the removal of an acetyl group from lysine at position 4 of the histone.	got7fsn_ti							al	2014-12-23T19:37:15Z						biological_process											owl:Class	
GO:1902734	biolink:NamedThing	regulation of receptor-mediated virion attachment to host cell	Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell.	got7fsn_ti	regulation of virion attachment, binding of host cell surface receptor						als	2014-02-25T12:25:56Z						biological_process											owl:Class	
GO:0046710	biolink:NamedThing	GDP metabolic process	The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate.	got7fsn_ti	GDP metabolism													biological_process											owl:Class	
GO:0021889	biolink:NamedThing	olfactory bulb interneuron differentiation	The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.	got7fsn_ti														biological_process											owl:Class	
GO:0048906	biolink:NamedThing	anterior lateral line neuromast support cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.	got7fsn_ti														biological_process											owl:Class	
GO:0048901	biolink:NamedThing	anterior lateral line neuromast development	The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.	got7fsn_ti														biological_process											owl:Class	
GO:0072186	biolink:NamedThing	metanephric cap morphogenesis	The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.	got7fsn_ti							mah	2010-03-01T01:22:51Z						biological_process											owl:Class	
GO:0048223	biolink:NamedThing	hemicellulose network	Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan.	got7fsn_ti														cellular_component											owl:Class	
GO:0034402	biolink:NamedThing	recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex	The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0009319	biolink:NamedThing	cytochrome o ubiquinol oxidase complex	A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups.	got7fsn_ti					See also the molecular function term 'cytochrome o ubiquinol oxidase activity ; GO:0008827'.							MetaCyc:CYT-O-UBIOX-CPLX		cellular_component											owl:Class	
GO:1990513	biolink:NamedThing	CLOCK-BMAL transcription complex	Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms.	got7fsn_ti	CLOCK/BMAL complex				An example of this is CLOCK in human (O15516) in PMID:23229515 (inferred from physical interaction).		bhm	2014-10-08T13:10:24Z						cellular_component											owl:Class	
GO:0015207	biolink:NamedThing	adenine transmembrane transporter activity	Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-5672027|RHEA:34999|Reactome:R-HSA-163215		molecular_function											owl:Class	
GO:0015853	biolink:NamedThing	adenine transport	The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	adenine transmembrane transport													biological_process											owl:Class	
GO:0044312	biolink:NamedThing	crystalloid	A transient, cytoplasmic organelle found in Plasmodium species that resembles a cytoplasmic inclusion body and whose function is poorly understood. Crystalloids form in ookinetes and disappear after ookinete-to-oocyst transformation.	got7fsn_ti							jl	2010-02-18T03:58:55Z						cellular_component											owl:Class	
GO:1901630	biolink:NamedThing	negative regulation of presynaptic membrane organization	Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization.	got7fsn_ti	down regulation of presynaptic membrane organization|inhibition of presynaptic membrane organization|negative regulation of pre-synaptic membrane organization|downregulation of presynaptic membrane organization|down-regulation of presynaptic membrane organisation|down regulation of presynaptic membrane organisation|down-regulation of presynaptic membrane organization|downregulation of presynaptic membrane organisation|inhibition of presynaptic membrane organisation|negative regulation of presynaptic membrane organisation						ans	2012-11-15T11:40:36Z						biological_process											owl:Class	
GO:0045497	biolink:NamedThing	female analia development	The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0071254	biolink:NamedThing	cytoplasmic U snRNP body	A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.	got7fsn_ti	U body|U-body						mah	2009-12-04T10:31:29Z						cellular_component											owl:Class	
GO:0001547	biolink:NamedThing	antral ovarian follicle growth	Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.	got7fsn_ti														biological_process											owl:Class	
GO:0080157	biolink:NamedThing	regulation of plant-type cell wall organization or biogenesis	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.	got7fsn_ti	regulation of plant-type cell wall organisation or biogenesis						dhl	2010-09-01T04:02:37Z						biological_process											owl:Class	
GO:1904513	biolink:NamedThing	negative regulation of initiation of premeiotic DNA replication	Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication.	got7fsn_ti	down regulation of initiation of premeiotic DNA replication|down-regulation of initiation of premeiotic DNA synthesis|down regulation of premeiotic DNA replication initiation|negative regulation of meiotic DNA replication initiation|downregulation of initiation of premeiotic DNA replication|down-regulation of initiation of premeiotic DNA replication|down regulation of meiotic DNA replication initiation|inhibition of initiation of premeiotic DNA synthesis|inhibition of initiation of meiotic DNA synthesis|down-regulation of premeiotic DNA replication initiation|inhibition of meiotic DNA replication initiation|down-regulation of initiation of meiotic DNA synthesis|downregulation of meiotic DNA replication initiation|downregulation of premeiotic DNA replication initiation|negative regulation of premeiotic DNA replication initiation|down regulation of initiation of premeiotic DNA synthesis|down regulation of initiation of meiotic DNA synthesis|inhibition of premeiotic DNA replication initiation|down-regulation of meiotic DNA replication initiation|downregulation of initiation of meiotic DNA synthesis|negative regulation of initiation of meiotic DNA synthesis|inhibition of initiation of premeiotic DNA replication|downregulation of initiation of premeiotic DNA synthesis|negative regulation of initiation of premeiotic DNA synthesis						mah	2015-07-28T12:59:23Z						biological_process											owl:Class	
GO:0039692	biolink:NamedThing	single stranded viral RNA replication via double stranded DNA intermediate	A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II.	got7fsn_ti	viral ssRNA replication via dsDNA intermediate|retroviral genome replication						bf	2013-10-17T15:59:43Z			GO:0045090	VZ:1937		biological_process											owl:Class	
GO:0039695	biolink:NamedThing	DNA-templated viral transcription	A transcription process that uses a viral DNA as a template.	got7fsn_ti							bf	2013-10-28T13:25:20Z				VZ:1942		biological_process											owl:Class	
GO:0061224	biolink:NamedThing	mesonephric glomerulus development	The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.	got7fsn_ti							dph	2010-08-19T01:26:00Z						biological_process											owl:Class	
GO:0036126	biolink:NamedThing	sperm flagellum	A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.	got7fsn_ti	sperm cilium|sperm tail				Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is always 'flagellum', hence the primary term name, but the cilium parentage is deliberate.		bf	2012-02-28T02:39:00Z						cellular_component											owl:Class	
GO:0019035	biolink:NamedThing	viral integration complex	A nucleoprotein complex containing viral genetic material and the viral integrase, required for genome integration into the host's genome. May contain other proteins.	got7fsn_ti	pre-integration complex|PIC	https://github.com/geneontology/go-ontology/issues/19806										Wikipedia:Pre-integration_complex		cellular_component											owl:Class	
GO:0043657	biolink:NamedThing	host cell	A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19800												cellular_component											owl:Class	
GO:0010106	biolink:NamedThing	cellular response to iron ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.	got7fsn_ti														biological_process											owl:Class	
GO:0021683	biolink:NamedThing	cerebellar granular layer morphogenesis	The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	got7fsn_ti														biological_process											owl:Class	
GO:0010319	biolink:NamedThing	stromule	Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types.	got7fsn_ti	Stroma-filled tubule											Wikipedia:Stromule		cellular_component											owl:Class	
GO:0030325	biolink:NamedThing	adrenal gland development	The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.	got7fsn_ti	interrenal gland													biological_process											owl:Class	
GO:0045829	biolink:NamedThing	negative regulation of isotype switching	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.	got7fsn_ti	negative regulation of class switching|inhibition of isotype switching|negative regulation of isotype switch recombination|down regulation of isotype switching|negative regulation of class switch recombination|downregulation of isotype switching|down-regulation of isotype switching													biological_process											owl:Class	
GO:0030176	biolink:NamedThing	integral component of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	ER integral membrane protein|integral to ER membrane|integral to endoplasmic reticulum membrane													cellular_component											owl:Class	
CL:0000096	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009348	biolink:NamedThing	ornithine carbamoyltransferase complex	A homotrimeric protein complex that catalyzes the transfer of a carbamoyl group to ornithine, forming citrulline.	got7fsn_ti														cellular_component											owl:Class	
GO:0042658	biolink:NamedThing	MHC class II protein binding, via antigen binding groove	Binding to the antigen binding groove of major histocompatibility complex class II molecules.	got7fsn_ti	major histocompatibility complex class II protein binding, via antigen binding groove													molecular_function											owl:Class	
GO:0005693	biolink:NamedThing	U12 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U12, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U12 snRNP, most of which remain associated with the U12 snRNA both while the U12 snRNP is free or assembled into a series of spliceosomal complexes.	got7fsn_ti	snRNP U12													cellular_component											owl:Class	
GO:0042896	biolink:NamedThing	chloramphenicol transmembrane transporter activity	Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other.	got7fsn_ti	chloramphenicol transporter activity													molecular_function											owl:Class	
GO:0042892	biolink:NamedThing	chloramphenicol transmembrane transport	The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	chloramphenicol transport													biological_process											owl:Class	
GO:0032123	biolink:NamedThing	deep fiber	Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm.	got7fsn_ti	deep fibre													cellular_component											owl:Class	
GO:0031912	biolink:NamedThing	oral apparatus	Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems.	got7fsn_ti					Note that this term refers to a subcellular structure characteristic of ciliate protozoans, and should not be confused with oral anatomical structures of multicellular animals.									cellular_component											owl:Class	
GO:0030332	biolink:NamedThing	cyclin binding	Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.	got7fsn_ti														molecular_function											owl:Class	
GO:1990193	biolink:NamedThing	BtuCD complex	Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer.	got7fsn_ti	cobalamin transport complex, core subunit|BtuC-BtuD complex|vitamin B12 transport complex, core subunit						bhm	2013-09-12T14:58:56Z						cellular_component											owl:Class	
GO:0042937	biolink:NamedThing	tripeptide transmembrane transporter activity	Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.	got7fsn_ti	tripeptide transporter activity													molecular_function											owl:Class	
GO:0042939	biolink:NamedThing	tripeptide transport	The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0033286	biolink:NamedThing	ATPase-coupled ectoine transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out).	got7fsn_ti	ATP-dependent ectoine transmembrane transporter activity|ectoine transmembrane transporter activity|ectoine-transporting ATPase activity										GO:0051471	RHEA:32787		molecular_function											owl:Class	
GO:0051470	biolink:NamedThing	ectoine transport	The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria.	got7fsn_ti														biological_process											owl:Class	
GO:0003281	biolink:NamedThing	ventricular septum development	The progression of the ventricular septum over time from its formation to the mature structure.	got7fsn_ti	septum inferius development|interventricular septum development						dph	2009-10-20T10:04:51Z						biological_process											owl:Class	
GO:0045248	biolink:NamedThing	cytosolic oxoglutarate dehydrogenase complex	A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).	got7fsn_ti					See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.									cellular_component											owl:Class	
GO:0004849	biolink:NamedThing	uridine kinase activity	Catalysis of the reaction: ATP + uridine = ADP + UMP.	got7fsn_ti	uridine-cytidine kinase activity|uridine monophosphokinase activity|uridine kinase reaction|ATP:uridine 5'-phosphotransferase activity|pyrimidine ribonucleoside kinase activity|uridine phosphokinase activity|uridine kinase (phosphorylating)											EC:2.7.1.48|MetaCyc:URIDINEKIN-RXN|Reactome:R-HSA-8954327|RHEA:16825		molecular_function											owl:Class	
GO:0006222	biolink:NamedThing	UMP biosynthetic process	The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.	got7fsn_ti	UMP synthesis|UMP biosynthesis|UMP formation|UMP anabolism													biological_process											owl:Class	
GO:0021746	biolink:NamedThing	solitary nucleus development	The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0045268	biolink:NamedThing	plasma membrane proton-transporting ATP synthase, catalytic core	The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. Examples of this component are found in Bacterial species.	got7fsn_ti	proton-transporting ATP synthase, catalytic core|hydrogen-transporting ATP synthase, catalytic core													cellular_component											owl:Class	
GO:0014020	biolink:NamedThing	primary neural tube formation	The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.	got7fsn_ti	primary neurulation|primary neural tube morphogenesis													biological_process											owl:Class	
GO:0046817	biolink:NamedThing	chemokine receptor antagonist activity	Interacts with chemokine receptors to reduce the action of a chemokine.	got7fsn_ti														molecular_function											owl:Class	
GO:0070100	biolink:NamedThing	negative regulation of chemokine-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.	got7fsn_ti	negative regulation of chemokine-mediated signalling pathway													biological_process											owl:Class	
GO:0009950	biolink:NamedThing	dorsal/ventral axis specification	The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.	got7fsn_ti	dorsal/ventral axis determination|dorsoventral axis specification|dorsal-ventral axis specification													biological_process											owl:Class	
GO:0002927	biolink:NamedThing	archaeosine-tRNA biosynthetic process	The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs.	got7fsn_ti					Archaeosine (7-formamidino-7-deazaguanosine) is a structural variant of the hypermodified nucleoside 7-deazaguanosine. The biosynthesis pathway starts with archaeosine tRNA-guanine transglycosylase (ArcTGT) which catalyzes the exchange of guanine at position 15 in the D-loop of archaeal tRNAs with a free 7-cyano-7-deazaguanine.		hjd	2012-01-18T03:06:27Z						biological_process											owl:Class	
GO:0043867	biolink:NamedThing	7-cyano-7-deazaguanine tRNA-ribosyltransferase activity	Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine.	got7fsn_ti	TgtA|archaeal tRNA-guanine transglycosylase activity|archaeosine tRNA-ribosyltransferase activity													molecular_function											owl:Class	
GO:2000240	biolink:NamedThing	positive regulation of tRNA export from nucleus	Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus.	got7fsn_ti	positive regulation of tRNA export from cell nucleus|positive regulation of tRNA transport from nucleus to cytoplasm|positive regulation of tRNA-nucleus export|positive regulation of tRNA export out of nucleus						mah	2010-11-10T12:39:38Z						biological_process											owl:Class	
GO:0035437	biolink:NamedThing	maintenance of protein localization in endoplasmic reticulum	Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.	got7fsn_ti	maintenance of protein localisation in endoplasmic reticulum|maintenance of protein localization in ER|maintenance of protein location in endoplasmic reticulum|retention of protein in endoplasmic reticulum|maintenance of protein location in ER|protein-endoplasmic reticulum retention|retention of protein in ER|protein-ER retention						bf	2010-04-09T10:39:49Z						biological_process											owl:Class	
GO:0046598	biolink:NamedThing	positive regulation of viral entry into host cell	Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.	got7fsn_ti	positive regulation of viral penetration into host cell													biological_process											owl:Class	
GO:0002625	biolink:NamedThing	regulation of T cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.	got7fsn_ti	regulation of T-lymphocyte antigen processing and presentation|regulation of T-cell antigen processing and presentation|regulation of T lymphocyte antigen processing and presentation													biological_process											owl:Class	
GO:0045509	biolink:NamedThing	interleukin-27 receptor activity	Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-27R|IL-27 receptor activity													molecular_function											owl:Class	
GO:0070106	biolink:NamedThing	interleukin-27-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-27 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-27-mediated signalling pathway|IL27RA/IL6ST signaling pathway|IL-27-mediated signaling pathway													biological_process											owl:Class	
GO:0008556	biolink:NamedThing	P-type potassium transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in).	got7fsn_ti	potassium ABC transporter|ATP phosphohydrolase (K+-importing)|potassium-importing ATPase activity|K(+)-importing ATPase activity|potassium-uptake-ATPase activity|ATP-dependent potassium transmembrane transporter activity|ATPase-coupled potassium transmembrane transporter activity|K+-importing ATPase activity|potassium-transporting ATPase activity|potassium transmembrane transporter activity, phosphorylative mechanism|potassium transporting ATPase activity|K+-transporting ATPase activity|K(+)-transporting ATPase activity										GO:0015618	EC:7.2.2.6|RHEA:16777		molecular_function											owl:Class	
GO:0003984	biolink:NamedThing	acetolactate synthase activity	Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.	got7fsn_ti	acetohydroxy acid synthetase activity|alpha-acetohydroxyacid synthase activity|acetolactic synthetase activity|pyruvate:pyruvate acetaldehydetransferase (decarboxylating)|alpha-acetolactate synthetase activity|acetohydroxyacid synthase activity|alpha-acetohydroxy acid synthetase activity|alpha-acetolactate synthase activity|acetolactate pyruvate-lyase (carboxylating) activity				Note that this function was formerly EC:4.1.3.18.							MetaCyc:ACETOLACTSYN-RXN|EC:2.2.1.6|RHEA:25249		molecular_function											owl:Class	
GO:1904378	biolink:NamedThing	maintenance of unfolded protein involved in ERAD pathway	Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome.	got7fsn_ti	maintenance of unfolded protein involved in ER-associated degradation pathway|holdase activity|ERAD chaperone-like activity|maintenance of unfolded protein during ERAD|maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation|maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway|chaperone holdase activity						bf	2015-06-23T09:21:53Z						biological_process											owl:Class	
GO:0031897	biolink:NamedThing	Tic complex	The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane.	got7fsn_ti	chloroplast inner membrane translocase complex													cellular_component											owl:Class	
GO:0003236	biolink:NamedThing	sinus venosus morphogenesis	The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.	got7fsn_ti							dph	2009-10-13T11:16:52Z						biological_process											owl:Class	
GO:0035182	biolink:NamedThing	female germline ring canal outer rim	An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues.	got7fsn_ti	ovarian ring canal outer rim|nurse cell ring canal outer rim|germline ring canal outer rim				See also the fly_anatomy.ontology term 'outer nurse cell ring canal rim ; FBbt:00004882'.									cellular_component											owl:Class	
GO:0035324	biolink:NamedThing	female germline ring canal	An intercellular bridge that connects the germline cells of a female cyst.	got7fsn_ti	ovarian ring canal|nurse cell ring canal						bf	2010-02-25T11:06:41Z						cellular_component											owl:Class	
GO:0140528	biolink:NamedThing	bilobe structure assembly	The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).	got7fsn_ti	bilobe structure formation|bilobe structure biogenesis|kinetoplastid flagellar hook complex assembly	https://github.com/geneontology/go-ontology/issues/20057					pg	2020-09-30T08:47:39Z						biological_process											owl:Class	
GO:1990964	biolink:NamedThing	actin cytoskeleton-regulatory complex	A protein complex probably required for the internalization of endosomes during actin-coupled endocytosis. Links the site of endocytosis to the cell membrane-associated actin cytoskeleton, coordinating ARP2/3 stimulation at the later stages of endocytosis. Present in the late endocytic coat.	got7fsn_ti					An example of this is Pan1 in Saccharomyces cerevisiae (UniProt ID P32521) in PMID:10594004 (inferred from direct assay).		bhm	2016-06-09T12:18:30Z						cellular_component											owl:Class	
GO:0048752	biolink:NamedThing	semicircular canal morphogenesis	The process in which the anatomical structures of the semicircular canals are generated and organized.	got7fsn_ti	embryonic semicircular canal morphogenesis													biological_process											owl:Class	
GO:0034085	biolink:NamedThing	establishment of sister chromatid cohesion	The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase.	got7fsn_ti														biological_process											owl:Class	
GO:2000649	biolink:NamedThing	regulation of sodium ion transmembrane transporter activity	Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.	got7fsn_ti	regulation of sodium transporter activity						yaf	2011-04-28T08:42:53Z						biological_process											owl:Class	
GO:0010093	biolink:NamedThing	specification of floral organ identity	The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:2000791	biolink:NamedThing	negative regulation of mesenchymal cell proliferation involved in lung development	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.	got7fsn_ti							pr	2011-06-24T01:53:53Z						biological_process											owl:Class	
GO:0060786	biolink:NamedThing	regulation of cell differentiation involved in tissue homeostasis	Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.	got7fsn_ti							dph	2009-07-31T01:55:19Z						biological_process											owl:Class	
GO:0003061	biolink:NamedThing	positive regulation of the force of heart contraction by norepinephrine	The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction.	got7fsn_ti	increased force of heart contraction by norepinephrine|positive regulation of heart contraction by norepinephrine|positive regulation of heart contraction by adrenaline|noradrenaline cardiac inotropy|noradrenaline regulation of the strength of heart muscle contraction|norepinephrine cardiac inotropy|increased force of heart contraction by adrenaline													biological_process											owl:Class	
GO:0001997	biolink:NamedThing	positive regulation of the force of heart contraction by epinephrine-norepinephrine	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings.	got7fsn_ti	increased force of heart contraction by epinephrine-norepinephrine|increased force of heart contraction by adrenaline-noradrenaline|positive regulation of heart contraction by adrenaline-noradrenaline|increased inotropy by epinephrine-norepinephrine|positive regulation of heart contraction by epinephrine-norepinephrine|increased strength of cardiac contraction by epinephrine-norepinephrine													biological_process											owl:Class	
GO:0061641	biolink:NamedThing	CENP-A containing chromatin organization	Any process that results in the specification, formation or maintenance of the physical structure of CENP-A containing chromatin.	got7fsn_ti	centromeric chromatin organization						dph	2014-08-27T12:26:14Z						biological_process											owl:Class	
GO:0020030	biolink:NamedThing	infected host cell surface knob	Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.	got7fsn_ti														cellular_component											owl:Class	
NCBITaxon:5820	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032545	biolink:NamedThing	CURI complex	A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p.	got7fsn_ti														cellular_component											owl:Class	
GO:0001927	biolink:NamedThing	exocyst assembly	The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex.	got7fsn_ti														biological_process											owl:Class	
GO:0071515	biolink:NamedThing	genetic imprinting at mating-type locus	A genetic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.	got7fsn_ti	mating type determination, imprinting						mah	2010-01-06T12:58:56Z						biological_process											owl:Class	
GO:0097684	biolink:NamedThing	dinoflagellate antapex	The anterior most point of a dinoflagellate hypocone.	got7fsn_ti	antapex				The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-12-18T09:32:10Z						cellular_component											owl:Class	
GO:0097614	biolink:NamedThing	dinoflagellate hypocone	The part of a dinoflagellate cell below the cingulum; also referred to as the posterior portion of a dinoflagellate cell. It is separated from the epicone by the cingulum.	got7fsn_ti	hypocone|hypotheca|hyposome				The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-06-09T11:35:07Z						cellular_component											owl:Class	
GO:1904416	biolink:NamedThing	negative regulation of xenophagy	Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy.	got7fsn_ti	down-regulation of xenophagy|inhibition of xenophagy|downregulation of xenophagy|down regulation of xenophagy				An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype).		pad	2015-06-29T12:30:53Z						biological_process											owl:Class	
GO:0031953	biolink:NamedThing	negative regulation of protein autophosphorylation	Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.	got7fsn_ti	inhibition of protein amino acid autophosphorylation|down regulation of protein amino acid autophosphorylation|down-regulation of protein amino acid autophosphorylation|downregulation of protein amino acid autophosphorylation|negative regulation of protein amino acid autophosphorylation													biological_process											owl:Class	
GO:0009429	biolink:NamedThing	bacterial-type flagellum basal body, proximal rod	The portion of the central rod of the bacterial-type flagellar basal body that is proximal to the cell membrane; the proximal rod connects the distal rod to the flagellar motor.	got7fsn_ti	flagellar basal body, proximal rod|flagellin-based flagellum basal body, proximal rod													cellular_component											owl:Class	
GO:0098802	biolink:NamedThing	plasma membrane signaling receptor complex	Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									cellular_component											owl:Class	
GO:0046607	biolink:NamedThing	positive regulation of centrosome cycle	Any process that activates or increases the frequency, rate or extent of the centrosome cycle.	got7fsn_ti	upregulation of centrosome cycle|stimulation of centrosome cycle|up-regulation of centrosome cycle|activation of centrosome cycle|up regulation of centrosome cycle													biological_process											owl:Class	
GO:0007010	biolink:NamedThing	cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.	got7fsn_ti	cytoskeletal regulator activity|cytoskeletal organization and biogenesis|cytoskeleton organization and biogenesis|cytoskeleton organisation													biological_process											owl:Class	
GO:1903683	biolink:NamedThing	positive regulation of epithelial cell-cell adhesion involved in epithelium migration	Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.	got7fsn_ti	up-regulation of epithelial cell-cell adhesion involved in epithelium migration|upregulation of epithelial cell-cell adhesion involved in epithelium migration|up regulation of epithelial cell-cell adhesion involved in epithelium migration|activation of epithelial cell-cell adhesion involved in epithelium migration						als	2014-12-01T13:25:22Z						biological_process											owl:Class	
GO:0008086	biolink:NamedThing	light-activated voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	light-activated voltage-dependent calcium channel activity|light-activated voltage gated calcium channel activity													molecular_function											owl:Class	
GO:0099635	biolink:NamedThing	voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels	Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels.  This is the first step in synaptic transmission.	got7fsn_ti														molecular_function											owl:Class	
GO:0060330	biolink:NamedThing	regulation of response to interferon-gamma	Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.	got7fsn_ti	regulation of response to immune interferon|regulation of response to type II IFN|regulation of response to gamma-interferon|regulation of response to type II interferon													biological_process											owl:Class	
GO:0004326	biolink:NamedThing	tetrahydrofolylpolyglutamate synthase activity	Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).	got7fsn_ti	tetrahydrofolate synthase activity|folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity|FPGS activity|tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming)|folate polyglutamate synthetase activity|folylpolyglutamyl synthetase activity|tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity|folylpoly-gamma-glutamate synthase activity|formyltetrahydropteroyldiglutamate synthetase activity|folylpolyglutamate synthase activity|N10-formyltetrahydropteroyldiglutamate synthetase activity|folylpoly(gamma-glutamate) synthase activity|N(10)-formyltetrahydropteroyldiglutamate synthetase activity|folylpolyglutamate synthetase activity|tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)											Reactome:R-HSA-197958|MetaCyc:FOLYLPOLYGLUTAMATESYNTH-RXN|EC:6.3.2.17|Reactome:R-HSA-200681|RHEA:10580|Reactome:R-HSA-200682		molecular_function											owl:Class	
GO:0046901	biolink:NamedThing	tetrahydrofolylpolyglutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.	got7fsn_ti	tetrahydrofolylpolyglutamate synthesis|tetrahydrofolylpolyglutamate formation|tetrahydrofolate polyglutamylation|tetrahydrofolylpolyglutamate biosynthesis|tetrahydrofolyl-[Glu](n) biosynthesis|folic acid-containing compound polyglutamylation|THF polyglutamylation|tetrahydrofolylpolyglutamate anabolism|tetrahydrofolyl-[Glu](n) biosynthetic process													biological_process											owl:Class	
GO:0048767	biolink:NamedThing	root hair elongation	The process in which the root hair grows longer.	got7fsn_ti														biological_process											owl:Class	
GO:0051726	biolink:NamedThing	regulation of cell cycle	Any process that modulates the rate or extent of progression through the cell cycle.	got7fsn_ti	tumor suppressor|positive regulation of cell cycle arrest|arrest of mitotic cell cycle progression|mitotic cell cycle arrest|regulation of progression through cell cycle|cell cycle regulation|modulation of cell cycle progression|cell cycle modulation|regulation of cell cycle progression|negative regulation of cell cycle arrest|cell cycle regulator|regulation of cell cycle arrest|control of cell cycle progression|cell cycle arrest										GO:0071850|GO:0071156|GO:0007050|GO:0071158|GO:0071157|GO:0000074			biological_process											owl:Class	
GO:0043941	biolink:NamedThing	positive regulation of sexual sporulation resulting in formation of a cellular spore	Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0002177	biolink:NamedThing	manchette	A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments.	got7fsn_ti							hjd	2010-12-01T02:31:43Z						cellular_component											owl:Class	
GO:1990972	biolink:NamedThing	multimerin complex	Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures.	got7fsn_ti	Elastic microfibrillar interface 4 complex|p155 complex|EMILIN-3 complex|Multimerin-2 complex|Elastic microfibrillar interface 3 complex|Platelet glycoprotein Ia* complex|Multimerin-1 complex|EMILIN-4 complex				An example of this is Multimerin-1 in human (Q13201) in PMID:9454761.		bhm	2016-06-21T14:49:42Z						cellular_component											owl:Class	
GO:0033627	biolink:NamedThing	cell adhesion mediated by integrin	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.	got7fsn_ti	cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0005895	biolink:NamedThing	interleukin-5 receptor complex	A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3.	got7fsn_ti	IL-5 receptor complex													cellular_component											owl:Class	
GO:0060498	biolink:NamedThing	retinoic acid receptor signaling pathway involved in lung bud formation	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud.	got7fsn_ti	retinoic acid receptor signalling pathway involved in lung bud formation													biological_process											owl:Class	
GO:0001862	biolink:NamedThing	collectin binding	Binding to a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.	got7fsn_ti					Note that collectins include such proteins as mannose-binding lectins (MBL) and surfactant proteins A and D (SP-A and SP-D).									molecular_function											owl:Class	
GO:0035779	biolink:NamedThing	angioblast cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).	got7fsn_ti	angioblastic mesenchymal cell differentiation						bf	2011-04-04T11:10:38Z						biological_process											owl:Class	
GO:0015553	biolink:NamedThing	xanthosine transmembrane transporter activity	Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015863	biolink:NamedThing	xanthosine transport	The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0015125	biolink:NamedThing	bile acid transmembrane transporter activity	Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.	got7fsn_ti												Reactome:R-HSA-5661198|Reactome:R-HSA-194130|Reactome:R-HSA-194083|Reactome:R-HSA-194079|Reactome:R-HSA-5661184		molecular_function											owl:Class	
GO:0015721	biolink:NamedThing	bile acid and bile salt transport	The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	bile salt transport|bile acid transport													biological_process											owl:Class	
GO:0072197	biolink:NamedThing	ureter morphogenesis	The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.	got7fsn_ti							mah	2010-03-01T02:24:55Z						biological_process											owl:Class	
GO:0061410	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to ethanol	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an ethanol stimulus.	got7fsn_ti							dph	2012-01-12T12:17:35Z						biological_process											owl:Class	
GO:0071361	biolink:NamedThing	cellular response to ethanol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.	got7fsn_ti							mah	2009-12-11T03:02:59Z						biological_process											owl:Class	
GO:0071630	biolink:NamedThing	nuclear protein quality control by the ubiquitin-proteasome system	The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation.	got7fsn_ti	nucleus-associated proteasomal ubiquitin-dependent protein degradation|ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome|nucleus-associated proteasomal ubiquitin-dependent protein breakdown|nucleus-associated proteasomal ubiquitin-dependent protein catabolism				See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.		mah	2010-02-11T03:31:46Z						biological_process											owl:Class	
GO:0035775	biolink:NamedThing	pronephric glomerulus morphogenesis	The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.	got7fsn_ti					This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus.		bf	2011-04-04T10:59:28Z						biological_process											owl:Class	
GO:0039021	biolink:NamedThing	pronephric glomerulus development	The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.	got7fsn_ti					This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus.		bf	2010-07-02T10:13:38Z						biological_process											owl:Class	
GO:1903357	biolink:NamedThing	regulation of transcription initiation from RNA polymerase I promoter	Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter.	got7fsn_ti	regulation of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript						mah	2014-08-21T10:19:32Z						biological_process											owl:Class	
GO:2000302	biolink:NamedThing	positive regulation of synaptic vesicle exocytosis	Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.	got7fsn_ti							dph	2011-01-03T08:21:14Z						biological_process											owl:Class	
GO:0021638	biolink:NamedThing	trigeminal nerve formation	The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	got7fsn_ti	CN V formation|CN V biosynthesis													biological_process											owl:Class	
GO:1990819	biolink:NamedThing	actin fusion focus	A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.	got7fsn_ti							al	2015-08-10T16:52:15Z						cellular_component											owl:Class	
GO:0004900	biolink:NamedThing	erythropoietin receptor activity	Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0044697	biolink:NamedThing	HICS complex	A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins.	got7fsn_ti							jl	2012-09-19T13:30:22Z						cellular_component											owl:Class	
GO:0035880	biolink:NamedThing	embryonic nail plate morphogenesis	The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.	got7fsn_ti							bf	2011-05-31T02:38:57Z						biological_process											owl:Class	
GO:0034388	biolink:NamedThing	Pwp2p-containing subcomplex of 90S preribosome	A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.	got7fsn_ti	UTP-B complex|25-30 S subcomplex of 90S preribosome				Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.									cellular_component											owl:Class	
GO:0010433	biolink:NamedThing	bract morphogenesis	The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.	got7fsn_ti														biological_process											owl:Class	
GO:0060043	biolink:NamedThing	regulation of cardiac muscle cell proliferation	Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.	got7fsn_ti	regulation of cardiomyocyte proliferation|regulation of heart muscle cell proliferation													biological_process											owl:Class	
GO:0055017	biolink:NamedThing	cardiac muscle tissue growth	The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.	got7fsn_ti	heart muscle growth													biological_process											owl:Class	
GO:0007496	biolink:NamedThing	anterior midgut development	The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0007494	biolink:NamedThing	midgut development	The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0032069	biolink:NamedThing	regulation of nuclease activity	Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.	got7fsn_ti	nuclease regulator activity													biological_process											owl:Class	
GO:0033175	biolink:NamedThing	chloroplast proton-transporting ATP synthase complex, coupling factor CF(o)	All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins.	got7fsn_ti	chloroplast proton-transporting ATP synthase complex, coupling factor CF(0)|chloroplast proton-transporting F-type ATPase complex, coupling factor CF(o)													cellular_component											owl:Class	
GO:0042776	biolink:NamedThing	mitochondrial ATP synthesis coupled proton transport	The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.	got7fsn_ti	mitochondrial proton transport													biological_process											owl:Class	
GO:0071097	biolink:NamedThing	alphaV-beta3 integrin-paxillin-Pyk2 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.	got7fsn_ti	ITGAV-ITGB3-PXN-PTK2b complex						mah	2009-11-06T04:51:52Z						cellular_component											owl:Class	
GO:0072380	biolink:NamedThing	TRC complex	A protein complex found in yeast that contains GET4, MDY2 (GET5), SGT2, and at least two heat shock proteins, HSP104 and YBR137W. The TRC complex transfers tail-anchored (TA) proteins to GET3 for targeting to the endoplasmic reticulum membrane.	got7fsn_ti	TMD recognition complex|GET4-GET5 transmembrane domain recognition complex	https://github.com/geneontology/go-ontology/issues/20889					mah	2010-11-24T02:43:41Z						cellular_component											owl:Class	
GO:0015346	biolink:NamedThing	ferric triacetylfusarinine C:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in).	got7fsn_ti	ferric triacetylfusarinine C:hydrogen symporter activity													molecular_function											owl:Class	
GO:0015686	biolink:NamedThing	ferric triacetylfusarinine C import into cell	The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	ferric triacetylfusarinine C transport													biological_process											owl:Class	
GO:0060163	biolink:NamedThing	subpallium neuron fate commitment	The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon.	got7fsn_ti	subpallium neuronal precursor fate commitment													biological_process											owl:Class	
GO:1990184	biolink:NamedThing	amino acid transport complex	A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane.	got7fsn_ti							jl	2013-09-11T15:02:16Z						cellular_component											owl:Class	
GO:0110027	biolink:NamedThing	negative regulation of DNA strand resection involved in replication fork processing	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.	got7fsn_ti							kmv	2017-07-05T18:39:49Z						biological_process											owl:Class	
GO:0034091	biolink:NamedThing	regulation of maintenance of sister chromatid cohesion	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.	got7fsn_ti														biological_process											owl:Class	
GO:0044799	biolink:NamedThing	NarGHI complex	A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit.	got7fsn_ti	nitrate reductase A|cytoplasmic membrane-bound quinol-nitrate oxidoreductase						jl	2013-08-29T14:17:41Z						cellular_component											owl:Class	
GO:0048866	biolink:NamedThing	stem cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0001175	biolink:NamedThing	transcriptional start site selection at RNA polymerase III promoter	Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	got7fsn_ti							krc	2011-06-20T01:47:38Z						biological_process											owl:Class	
GO:1905616	biolink:NamedThing	regulation of miRNA mediated inhibition of translation	Any process that modulates the frequency, rate or extent of miRNA mediated inhibition of translation.	got7fsn_ti	regulation of gene silencing by miRNA, negative regulation of translation|regulation of downregulation of translation involved in gene silencing by miRNA|regulation of negative regulation of translation involved in gene silencing by microRNA|regulation of inhibition of translation involved in gene silencing by miRNA|regulation of down regulation of translation involved in gene silencing by miRNA|regulation of miRNA-mediated gene silencing, negative regulation of translation|regulation of down-regulation of translation involved in gene silencing by miRNA						bc	2016-10-28T11:47:49Z						biological_process											owl:Class	
GO:0050884	biolink:NamedThing	neuromuscular process controlling posture	Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.	got7fsn_ti	regulation of posture													biological_process											owl:Class	
GO:0060978	biolink:NamedThing	angiogenesis involved in coronary vascular morphogenesis	Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.	got7fsn_ti	coronary blood vessel angiogenesis|angiogenesis involved in heart vascular morphogenesis|angiogenesis involved in cardiac vascular morphogenesis|coronary vasculature angiogenesis						dph	2009-10-06T02:02:12Z						biological_process											owl:Class	
GO:0062092	biolink:NamedThing	Yae1-Lto1 complex	A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p.	got7fsn_ti							dph	2018-11-15T17:39:46Z						cellular_component											owl:Class	
GO:0008103	biolink:NamedThing	oocyte microtubule cytoskeleton polarization	Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster.	got7fsn_ti											GO:0048129			biological_process											owl:Class	
GO:0120021	biolink:NamedThing	oxysterol transfer activity	Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	intermembrane oxysterol transfer activity|oxysterol carrier activity	https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-17T04:50:30Z						molecular_function											owl:Class	
GO:0008142	biolink:NamedThing	oxysterol binding	Binding to oxysterol, an oxidized form of cholesterol.	got7fsn_ti														molecular_function											owl:Class	
GO:2000263	biolink:NamedThing	regulation of blood coagulation, extrinsic pathway	Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway.	got7fsn_ti							mah	2010-11-23T11:44:35Z						biological_process											owl:Class	
GO:0035846	biolink:NamedThing	oviduct epithelium development	The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.	got7fsn_ti	fallopian tube epithelium development						bf	2011-05-10T10:53:05Z						biological_process											owl:Class	
GO:0051178	biolink:NamedThing	meiotic chromosome decondensation	The cell cycle process in which chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells.	got7fsn_ti														biological_process											owl:Class	
GO:0052541	biolink:NamedThing	plant-type cell wall cellulose metabolic process	The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.	got7fsn_ti	cellulose and pectin-containing cell wall cellulose metabolic process|cell wall cellulose metabolism													biological_process											owl:Class	
GO:0005391	biolink:NamedThing	P-type sodium:potassium-exchanging transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).	got7fsn_ti	P-type sodium:potassium-exchanging ATPase activity|Na+/K+-ATPase activity|sodium pump|Na+,K+-ATPase activity|Na(+)/K(+)-exchanging ATPase activity|sodium/potassium-transporting ATPase activity|Na+/K+-exchanging ATPase activity|sodium:potassium exchanging ATPase activity|Na,K-activated ATPase activity|sodium/potassium-exchanging ATPase activity|Na(+)/K(+)-ATPase activity|sodium:potassium-exchanging ATPase activity	https://github.com/geneontology/go-ontology/issues/17289										Reactome:R-HSA-936897|Wikipedia:ATPase,_Na%2B/K%2B_transporting,_alpha_1|MetaCyc:3.6.3.9-RXN|EC:7.2.2.13|RHEA:18353|TC:3.A.3.1.1		molecular_function											owl:Class	
GO:0010248	biolink:NamedThing	establishment or maintenance of transmembrane electrochemical gradient	The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0043310	biolink:NamedThing	negative regulation of eosinophil degranulation	Any process that stops, prevents, or reduces the rate of eosinophil degranulation.	got7fsn_ti	down regulation of eosinophil degranulation|inhibition of eosinophil degranulation|negative regulation of eosinophil granule exocytosis|down-regulation of eosinophil degranulation|downregulation of eosinophil degranulation													biological_process											owl:Class	
GO:0016592	biolink:NamedThing	mediator complex	A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.	got7fsn_ti	L mediator complex|CDK8-containing TRAP/mediator complex|Srb-mediator complex|TRAP complex										GO:0000119	Wikipedia:Mediator_(coactivator)		cellular_component											owl:Class	
GO:0070847	biolink:NamedThing	core mediator complex	A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.	got7fsn_ti	C mediator complex|S mediator complex	https://github.com/geneontology/go-ontology/issues/15979					mah	2009-08-04T02:56:11Z						cellular_component											owl:Class	
GO:0097537	biolink:NamedThing	Y-shaped link	A Y-shaped protein complex in the ciliary transition zone that connects the cilium axoneme to the ciliary necklace. Both protein sorting and protein gating occur at this point in the cilium allowing some, but not all proteins to enter the cilium.	got7fsn_ti	Y-link structure|membrane-microtubule complex|Y-shaped linker|Y-shaped fibre|Y-shaped assemblage|Y-shaped fiber|Y-link						pr	2013-12-03T16:34:34Z						cellular_component											owl:Class	
GO:0050971	biolink:NamedThing	detection of mechanical stimulus involved in magnetoreception	The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field.	got7fsn_ti	magnetoreception, sensory detection of mechanical stimulus|sensory transduction of mechanical stimulus during magnetoreception|magnetoception, sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus during magnetoreception|magnetoreception, sensory transduction of mechanical stimulus|magnetoreception, detection of mechanical stimulus													biological_process											owl:Class	
GO:0050979	biolink:NamedThing	magnetoreception by sensory perception of mechanical stimulus	The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field.	got7fsn_ti	magnetoreception, using mechanical stimulus|magnetoreception through mechanical stimulus|magnetoreception, sensory perception of mechanical stimulus													biological_process											owl:Class	
GO:0042686	biolink:NamedThing	regulation of cardioblast cell fate specification	Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti														biological_process											owl:Class	
GO:0048756	biolink:NamedThing	sieve cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials.	got7fsn_ti														biological_process											owl:Class	
GO:0005966	biolink:NamedThing	cyclic-nucleotide phosphodiesterase complex	An enzyme complex that catalyzes the hydrolysis of bonds in a cyclic nucleotide.	got7fsn_ti	photoreceptor cyclic-nucleotide phosphodiesterase complex													cellular_component											owl:Class	
GO:0031664	biolink:NamedThing	regulation of lipopolysaccharide-mediated signaling pathway	Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.	got7fsn_ti	regulation of lipopolysaccharide-mediated signalling pathway|regulation of LPS-mediated signaling pathway													biological_process											owl:Class	
GO:0015626	biolink:NamedThing	L-diaminopimelate transmembrane transporter activity	Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid.	got7fsn_ti	L-diaminopimelate transporter activity|cystine/diaminopimelate porter activity													molecular_function											owl:Class	
GO:0015830	biolink:NamedThing	diaminopimelate transport	The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0046689	biolink:NamedThing	response to mercury ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.	got7fsn_ti	mercuric sensitivity/resistance|response to mercuric ion|response to mercury													biological_process											owl:Class	
GO:0048597	biolink:NamedThing	post-embryonic camera-type eye morphogenesis	The process in which the anatomical structures of the eye are generated and organized during post-embryonic development.	got7fsn_ti	post-embryonic eye morphogenesis|post-embryonic camera-style eye morphogenesis													biological_process											owl:Class	
GO:0038167	biolink:NamedThing	epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via activation of the transcription factor NF-kappaB.	got7fsn_ti	epidermal growth factor receptor signalling pathway via positive regulation of NF-kappaB transcription factor activity|EGFR signaling pathway via activation of NF-kappaB						bf	2012-05-15T11:49:30Z						biological_process											owl:Class	
GO:0015217	biolink:NamedThing	ADP transmembrane transporter activity	Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015866	biolink:NamedThing	ADP transport	The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0003204	biolink:NamedThing	cardiac skeleton development	The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.	got7fsn_ti	heart fibrous skeleton development						dph	2009-10-13T09:05:04Z						biological_process											owl:Class	
GO:0045664	biolink:NamedThing	regulation of neuron differentiation	Any process that modulates the frequency, rate or extent of neuron differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1905304	biolink:NamedThing	regulation of cardiac myofibril assembly	Any process that modulates the frequency, rate or extent of cardiac myofibril assembly.	got7fsn_ti	regulation of cardiac myofibril morphogenesis|regulation of cardiac myofibril development|regulation of heart myofibril assembly						rl	2016-07-06T10:01:49Z						biological_process											owl:Class	
GO:1990156	biolink:NamedThing	DnaB-DnaG complex	A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes.	got7fsn_ti	DnaB-DnaG primosome complex						bhm	2013-08-02T09:50:54Z						cellular_component											owl:Class	
GO:0015658	biolink:NamedThing	branched-chain amino acid transmembrane transporter activity	Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.	got7fsn_ti	branched-chain aliphatic amino acid transporter activity|valine/tyrosine/tryptophan permease activity|leucine/valine/isoleucine permease activity|branched-chain aliphatic amino acid transmembrane transporter activity										GO:1901240	Reactome:R-HSA-9672770		molecular_function											owl:Class	
GO:0015803	biolink:NamedThing	branched-chain amino acid transport	The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.	got7fsn_ti	branched-chain amino-acid anions transport|branched-chain aliphatic amino acid transport|branched-chain amino-acid anion transport										GO:1900755			biological_process											owl:Class	
GO:0015902	biolink:NamedThing	carbonyl cyanide m-chlorophenylhydrazone transport	The directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.	got7fsn_ti	CCCP transport													biological_process											owl:Class	
GO:2000746	biolink:NamedThing	regulation of defecation rhythm	Any process that modulates the frequency, rate or extent of defecation rhythm.	got7fsn_ti	regulation of defecation motor program|regulation of defecation cycle|regulation of DMP|regulation of defecation behavior						bf	2011-06-15T03:23:07Z						biological_process											owl:Class	
GO:0140132	biolink:NamedThing	iron-sulfur cluster carrier activity	Binding to an iron-sulfur cluster and delivering it to an acceptor molecule.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14539					pg	2017-11-10T08:55:38Z						molecular_function											owl:Class	
GO:0015615	biolink:NamedThing	D-allose-importing ATPase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in).	got7fsn_ti	D-allose porter activity													molecular_function											owl:Class	
GO:0015754	biolink:NamedThing	allose transmembrane transport	The process in which allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	got7fsn_ti	allose transport													biological_process											owl:Class	
GO:0060596	biolink:NamedThing	mammary placode formation	The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.	got7fsn_ti							dph	2009-05-13T11:55:20Z						biological_process											owl:Class	
GO:0098682	biolink:NamedThing	arciform density	An electron dense structure that anchors a synaptic ribbon to the presynaptic membrane.	got7fsn_ti							dos	2017-02-05T16:12:22Z						cellular_component											owl:Class	
GO:0014022	biolink:NamedThing	neural plate elongation	The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions.	got7fsn_ti														biological_process											owl:Class	
GO:0001839	biolink:NamedThing	neural plate morphogenesis	The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0010059	biolink:NamedThing	positive regulation of atrichoblast fate specification	Any process that induces or promotes atrichoblast fate specification.	got7fsn_ti	upregulation of atrichoblast fate|stimulation of atrichoblast fate|up regulation of atrichoblast fate|up-regulation of atrichoblast fate|activation of atrichoblast fate													biological_process											owl:Class	
GO:2000144	biolink:NamedThing	positive regulation of DNA-templated transcription, initiation	Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.	got7fsn_ti	positive regulation of DNA-dependent transcription, initiation|positive regulation of initiation of DNA-dependent transcription|positive regulation of transcription initiation, DNA-dependent|transactivation|transcriptional transactivation						mah	2010-10-01T09:11:43Z						biological_process											owl:Class	
GO:0044361	biolink:NamedThing	negative regulation of voltage-gated potassium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.	got7fsn_ti							jl	2011-10-27T02:11:52Z						biological_process											owl:Class	
GO:0071998	biolink:NamedThing	ascospore release from ascus	A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive.	got7fsn_ti	ascospore liberation						mah	2010-10-25T03:41:44Z						biological_process											owl:Class	
GO:0098046	biolink:NamedThing	type V protein secretion system complex	A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc).	got7fsn_ti	T5SS complex|autotransporter system complex				Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'.		bf	2012-08-01T10:05:49Z						cellular_component											owl:Class	
GO:1990902	biolink:NamedThing	new cell pole	The cell pole proximal to the most recent cell division.	got7fsn_ti							pr	2015-11-17T16:44:53Z						cellular_component											owl:Class	
GO:1990890	biolink:NamedThing	netrin receptor binding	Binding to a netrin receptor.	got7fsn_ti							kmv	2015-11-02T22:56:07Z						molecular_function											owl:Class	
GO:0099145	biolink:NamedThing	regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.	got7fsn_ti							dos	2017-06-09T18:49:26Z						biological_process											owl:Class	
GO:0048635	biolink:NamedThing	negative regulation of muscle organ development	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.	got7fsn_ti	downregulation of muscle development|down regulation of muscle development|inhibition of muscle development|down-regulation of muscle development													biological_process											owl:Class	
GO:0021695	biolink:NamedThing	cerebellar cortex development	The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	got7fsn_ti														biological_process											owl:Class	
GO:0009276	biolink:NamedThing	Gram-negative-bacterium-type cell wall	The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain.	got7fsn_ti	1-2nm peptidoglycan-based cell wall|cell wall inner membrane													cellular_component											owl:Class	
GO:0030313	biolink:NamedThing	cell envelope	An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.	got7fsn_ti												Wikipedia:Cell_envelope		cellular_component											owl:Class	
GO:0061387	biolink:NamedThing	regulation of extent of cell growth	Any process that modulates the extent of cell growth.	got7fsn_ti							dph	2011-07-14T10:15:42Z						biological_process											owl:Class	
GO:0009838	biolink:NamedThing	abscission	The controlled shedding of a body part.	got7fsn_ti												Wikipedia:Abscission		biological_process											owl:Class	
CL:0000617	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016490	biolink:NamedThing	structural constituent of peritrophic membrane	The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster.	got7fsn_ti	structural constituent of peritrophic matrix													molecular_function											owl:Class	
GO:0140495	biolink:NamedThing	migracytosis	A cell migration-dependent mechanism for releasing cellular contents.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19760					pg	2020-07-10T15:13:46Z						biological_process											owl:Class	
GO:0009512	biolink:NamedThing	cytochrome b6f complex	Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.	got7fsn_ti	cyt b6-f complex|cyt b(6)f complex|cyt b6f complex|cytochrome b(6)f complex|cytochrome b6-f complex|cyt b6/f complex|cytochrome b6/f complex											Wikipedia:Cytochrome_b6f_complex		cellular_component											owl:Class	
GO:0032766	biolink:NamedThing	NHE3/E3KARP/ACTN4 complex	A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments.	got7fsn_ti	NHE3/E3KARP/alpha-actinin complex													cellular_component											owl:Class	
GO:0120034	biolink:NamedThing	positive regulation of plasma membrane bounded cell projection assembly	Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13298					krc	2017-04-26T04:34:45Z						biological_process											owl:Class	
GO:0140233	biolink:NamedThing	intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential.	got7fsn_ti	intracellular cAMP activated cation channel activity involved in regulation of postsynaptic membrane potential	https://github.com/geneontology/synapse/issues/231			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-09T11:31:18Z						molecular_function											owl:Class	
GO:0007053	biolink:NamedThing	spindle assembly involved in male meiosis	The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0090481	biolink:NamedThing	pyrimidine nucleotide-sugar transmembrane transport	The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti	pyrimidine nucleotide-sugar membrane transport|pyrimidine nucleotide-sugar transport				Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2012-10-01T16:43:54Z			GO:0015781			biological_process											owl:Class	
GO:0002074	biolink:NamedThing	extraocular skeletal muscle development	The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.	got7fsn_ti														biological_process											owl:Class	
GO:0009873	biolink:NamedThing	ethylene-activated signaling pathway	A series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.	got7fsn_ti	ethylene mediated signaling pathway|ethylene signal transduction|ethene mediated signalling pathway|ethene mediated signaling pathway|ethylene signaling pathway|ethylene mediated signalling pathway													biological_process											owl:Class	
GO:0071369	biolink:NamedThing	cellular response to ethylene stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.	got7fsn_ti	cellular response to ethene stimulus						mah	2009-12-11T03:13:57Z						biological_process											owl:Class	
GO:0001756	biolink:NamedThing	somitogenesis	The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.	got7fsn_ti	formation of mesodermal clusters											Wikipedia:Somitogenesis		biological_process											owl:Class	
GO:0000462	biolink:NamedThing	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	got7fsn_ti	maturation of 18S rRNA										GO:1990041			biological_process											owl:Class	
GO:2000238	biolink:NamedThing	regulation of tRNA export from nucleus	Any process that modulates the frequency, rate or extent of tRNA export from nucleus.	got7fsn_ti	regulation of tRNA-nucleus export|regulation of tRNA transport from nucleus to cytoplasm|regulation of tRNA export from cell nucleus|regulation of tRNA export out of nucleus						mah	2010-11-10T12:39:33Z						biological_process											owl:Class	
GO:1903481	biolink:NamedThing	negative regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti	inhibition of actin filament organisation involved in mitotic actomyosin contractile ring assembly|inhibition of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|downregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|down-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|negative regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|downregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|downregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|down-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|negative regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|inhibition of actin filament organization involved in mitotic actomyosin contractile ring assembly						vw	2014-09-23T16:03:50Z						biological_process											owl:Class	
GO:0046815	biolink:NamedThing	genome retention in viral capsid	Any process in which the viral genome is retained within the capsid during genome cleavage and packaging.	got7fsn_ti														biological_process											owl:Class	
GO:0019079	biolink:NamedThing	viral genome replication	Any process involved directly in viral genome replication, including viral nucleotide metabolism.	got7fsn_ti	viral replication|sigma virus replication													biological_process											owl:Class	
GO:0003995	biolink:NamedThing	acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.	got7fsn_ti	long-chain acyl coenzyme A dehydrogenase activity|acyl-CoA reductase activity|acyl CoA dehydrogenase activity|acyl coenzyme A dehydrogenase activity|general acyl CoA dehydrogenase activity|medium-chain acyl-coenzyme A dehydrogenase activity|fatty-acyl-CoA dehydrogenase activity|fatty acyl coenzyme A dehydrogenase activity|medium-chain acyl-CoA dehydrogenase activity|long-chain acyl-CoA dehydrogenase activity|acyl-CoA:acceptor 2,3-oxidoreductase activity|acyl-CoA:(acceptor) 2,3-oxidoreductase activity|acyl dehydrogenase activity										GO:0019109	Reactome:R-HSA-77263|Reactome:R-HSA-70859|Reactome:R-HSA-5695989|Reactome:R-HSA-77319|Reactome:R-HSA-109341|Reactome:R-HSA-77327|EC:1.3.99.3|Reactome:R-HSA-70800|Reactome:R-HSA-77299|Reactome:R-HSA-77338|Reactome:R-HSA-77345|MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN|Reactome:R-HSA-77274|MetaCyc:ACYLCOADEHYDROG-RXN|Reactome:R-HSA-5695980		molecular_function											owl:Class	
GO:0007547	biolink:NamedThing	germ-line processes downstream of sex determination signal	The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways.	got7fsn_ti														biological_process											owl:Class	
GO:0018992	biolink:NamedThing	germ-line sex determination	The determination of sex and sexual phenotype in an organism's germ line.	got7fsn_ti														biological_process											owl:Class	
GO:0098045	biolink:NamedThing	virus baseplate assembly	The aggregation, arrangement and bonding together of a set of components to form a virus baseplate.	got7fsn_ti							bm	2012-07-25T14:50:32Z						biological_process											owl:Class	
GO:0098003	biolink:NamedThing	viral tail assembly	The aggregation, arrangement and bonding together of a set of components to form a virus tail.	got7fsn_ti	bacteriophage tail assembly|virus tail assembly						bm	2012-07-18T16:01:59Z						biological_process											owl:Class	
GO:0033551	biolink:NamedThing	monopolin complex	A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits.	got7fsn_ti	Pcs1/Mde4 complex|monopolin subcomplex Csm1/Lrs4													cellular_component											owl:Class	
GO:0010480	biolink:NamedThing	microsporocyte differentiation	The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.	got7fsn_ti	pollen mother cell differentiation													biological_process											owl:Class	
GO:0043540	biolink:NamedThing	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis.	got7fsn_ti	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 complex				Note that we use this single class to represent all 4 isoforms of this complex. We decided to do this because the isoforms do not differ in function, rather in expression and regulation. We may want to revisit this in future.									cellular_component											owl:Class	
GO:0061621	biolink:NamedThing	canonical glycolysis	The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the  chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.	got7fsn_ti							dph	2014-04-14T09:21:54Z				MetaCyc:PWY66-400|Wikipedia:Glycolysis|Reactome:R-HSA-70171|MetaCyc:ANAGLYCOLYSIS-PWY		biological_process											owl:Class	
GO:0036186	biolink:NamedThing	early phagosome membrane	The lipid bilayer surrounding an early phagosome.	got7fsn_ti	early phagocytic vesicle membrane						bf	2012-04-16T02:37:30Z						cellular_component											owl:Class	
GO:0032009	biolink:NamedThing	early phagosome	A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.	got7fsn_ti	early phagocytic vesicle													cellular_component											owl:Class	
GO:1990590	biolink:NamedThing	ATF1-ATF4 transcription factor complex	Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway.	got7fsn_ti					An example of this is ATF1in human (P18846) in PMID:12871976 (inferred from physical interaction).		bhm	2014-12-15T14:25:56Z						cellular_component											owl:Class	
GO:0017055	biolink:NamedThing	negative regulation of RNA polymerase II transcription preinitiation complex assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.	got7fsn_ti	negative regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|inhibition of RNA polymerase II transcriptional preinitiation complex assembly|downregulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional preinitiation complex assembly|down-regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional pre-initiation complex assembly|negative regulation of RNA polymerase II transcriptional preinitiation complex formation|down regulation of RNA polymerase II transcriptional preinitiation complex assembly													biological_process											owl:Class	
GO:0048441	biolink:NamedThing	petal development	The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.	got7fsn_ti											GO:0048417			biological_process											owl:Class	
GO:0062049	biolink:NamedThing	protein phosphatase inhibitor complex	A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase.	got7fsn_ti							dph	2018-05-30T19:03:26Z						cellular_component											owl:Class	
GO:0035308	biolink:NamedThing	negative regulation of protein dephosphorylation	Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.	got7fsn_ti	down regulation of protein amino acid dephosphorylation|downregulation of protein amino acid dephosphorylation|inhibition of protein amino acid dephosphorylation|down-regulation of protein amino acid dephosphorylation|negative regulation of protein amino acid dephosphorylation													biological_process											owl:Class	
GO:0090261	biolink:NamedThing	positive regulation of inclusion body assembly	Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	got7fsn_ti							tb	2010-02-03T04:23:54Z						biological_process											owl:Class	
GO:0072087	biolink:NamedThing	renal vesicle development	The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.	got7fsn_ti							mah	2010-02-08T01:18:31Z						biological_process											owl:Class	
GO:0033365	biolink:NamedThing	protein localization to organelle	A process in which a protein is transported to, or maintained in, a location within an organelle.	got7fsn_ti	protein localization in organelle|protein localisation to organelle													biological_process											owl:Class	
GO:0021628	biolink:NamedThing	olfactory nerve formation	The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	got7fsn_ti	CN I formation|CN I biosynthesis													biological_process											owl:Class	
GO:0010346	biolink:NamedThing	shoot axis formation	The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti	shoot formation													biological_process											owl:Class	
GO:0048886	biolink:NamedThing	neuromast hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0009620	biolink:NamedThing	response to fungus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.	got7fsn_ti	response to fungi										GO:0009621			biological_process											owl:Class	
GO:0015695	biolink:NamedThing	organic cation transport	The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.	got7fsn_ti														biological_process											owl:Class	
GO:0008282	biolink:NamedThing	inward rectifying potassium channel	A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity.	got7fsn_ti	ATP-sensitive potassium channel complex|Kir6.1-SURx complex|Kir6.x complex|KCNJ11-SUR complex|Kir6.1-SUR complex|Kir6.2-SURx complex|KCNJ8-SURx complex|Kir6.x-SURx complex|KCNJ8-SUR complex|inward rectifying K+ channel|KCNJ11-SURx complex|Kir6-SUR complex|Kir6.2-SUR complex													cellular_component											owl:Class	
GO:0016515	biolink:NamedThing	interleukin-13 receptor activity	Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-13 receptor activity|IL-13R													molecular_function											owl:Class	
GO:0035772	biolink:NamedThing	interleukin-13-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-13 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-13-mediated signaling pathway|interleukin-13-mediated signalling pathway						bf	2011-04-01T11:00:11Z						biological_process											owl:Class	
GO:0034469	biolink:NamedThing	Golgi stack lumen	The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex.	got7fsn_ti														cellular_component											owl:Class	
GO:2000142	biolink:NamedThing	regulation of DNA-templated transcription, initiation	Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.	got7fsn_ti	regulation of transcription initiation, DNA-dependent|regulation of initiation of DNA-dependent transcription|regulation of DNA-dependent transcription, initiation						mah	2010-10-01T09:11:35Z						biological_process											owl:Class	
GO:0014058	biolink:NamedThing	negative regulation of acetylcholine secretion, neurotransmission	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.	got7fsn_ti	downregulation of acetylcholine secretion|down regulation of acetylcholine secretion|inhibition of acetylcholine secretion|down-regulation of acetylcholine secretion													biological_process											owl:Class	
GO:0046811	biolink:NamedThing	histone deacetylase inhibitor activity	Binds to and stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.	got7fsn_ti														molecular_function											owl:Class	
GO:0031064	biolink:NamedThing	negative regulation of histone deacetylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones.	got7fsn_ti	inhibition of histone deacetylation|down-regulation of histone deacetylation|down regulation of histone deacetylation|downregulation of histone deacetylation													biological_process											owl:Class	
GO:0008340	biolink:NamedThing	determination of adult lifespan	The control of viability and duration in the adult phase of the life-cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0010259	biolink:NamedThing	multicellular organism aging	An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).	got7fsn_ti														biological_process											owl:Class	
GO:1990934	biolink:NamedThing	nucleolus-like body	A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles.	got7fsn_ti	compact nucleolus|NLB|nucleolus-like body						sl	2016-03-21T21:28:14Z						cellular_component											owl:Class	
GO:0019080	biolink:NamedThing	viral gene expression	A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.	got7fsn_ti	viral genome expression													biological_process											owl:Class	
GO:0031674	biolink:NamedThing	I band	A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.	got7fsn_ti	I disc|isotropic disc|J disc											Wikipedia:Sarcomere#bands		cellular_component											owl:Class	
GO:0045972	biolink:NamedThing	negative regulation of juvenile hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone.	got7fsn_ti	downregulation of juvenile hormone secretion|down-regulation of juvenile hormone secretion|inhibition of juvenile hormone secretion|down regulation of juvenile hormone secretion													biological_process											owl:Class	
GO:0000290	biolink:NamedThing	deadenylation-dependent decapping of nuclear-transcribed mRNA	Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.	got7fsn_ti	deadenylation-dependent decapping of nuclear mRNA|deadenylylation-dependent decapping													biological_process											owl:Class	
GO:0003237	biolink:NamedThing	sinus venosus formation	The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.	got7fsn_ti							dph	2009-10-13T11:18:34Z						biological_process											owl:Class	
GO:0005945	biolink:NamedThing	6-phosphofructokinase complex	A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.	got7fsn_ti														cellular_component											owl:Class	
GO:0038092	biolink:NamedThing	nodal signaling pathway	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	nodal signaling|nodal signalling pathway						bf	2012-02-16T02:44:02Z						biological_process											owl:Class	
GO:0060655	biolink:NamedThing	branching involved in mammary gland cord morphogenesis	The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.	got7fsn_ti							dph	2009-05-29T09:29:32Z						biological_process											owl:Class	
GO:0048407	biolink:NamedThing	platelet-derived growth factor binding	Binding to platelet-derived growth factor.	got7fsn_ti	PDGF binding													molecular_function											owl:Class	
GO:0061780	biolink:NamedThing	mitotic cohesin loading	The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.	got7fsn_ti							dph	2016-08-23T13:00:34Z						biological_process											owl:Class	
GO:0034087	biolink:NamedThing	establishment of mitotic sister chromatid cohesion	The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0030386	biolink:NamedThing	ferredoxin-thioredoxin reductase complex	A protein complex that possesses ferredoxin-thioredoxin reductase activity.	got7fsn_ti	ferredoxin:thioredoxin reductase complex				Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'ferredoxin-thioredoxin reductase activity ; GO:0103012'.									cellular_component											owl:Class	
NCBITaxon:Union_0000002	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990569	biolink:NamedThing	UDP-N-acetylglucosamine transmembrane transport	The process in which UDP-N-acetylglucosamine is transported across a membrane.	got7fsn_ti	UDP-N-acetylglucosamine transport						vw	2014-11-27T11:56:35Z			GO:0015788			biological_process											owl:Class	
GO:0032293	biolink:NamedThing	non-myelinated axon ensheathment in central nervous system	The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system.	got7fsn_ti	ensheathment of non-myelinated axons in central nervous system													biological_process											owl:Class	
GO:0007508	biolink:NamedThing	larval heart development	The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.	got7fsn_ti														biological_process											owl:Class	
GO:0033111	biolink:NamedThing	attachment organelle membrane	The lipid bilayer surrounding an attachment organelle.  This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0033099	biolink:NamedThing	attachment organelle	A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division.	got7fsn_ti														cellular_component											owl:Class	
GO:0034463	biolink:NamedThing	90S preribosome assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.	got7fsn_ti														biological_process											owl:Class	
GO:0010632	biolink:NamedThing	regulation of epithelial cell migration	Any process that modulates the frequency, rate or extent of epithelial cell migration.	got7fsn_ti														biological_process											owl:Class	
GO:0019974	biolink:NamedThing	interleukin-14 binding	Binding to interleukin-14.	got7fsn_ti	IL-14 binding													molecular_function											owl:Class	
GO:0021648	biolink:NamedThing	vestibulocochlear nerve morphogenesis	The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	got7fsn_ti	CN VIII morphogenesis													biological_process											owl:Class	
GO:0021562	biolink:NamedThing	vestibulocochlear nerve development	The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	got7fsn_ti	CN VIII development|cranial nerve 8 development|cranial nerve VIII development|acoustic nerve development													biological_process											owl:Class	
GO:1990826	biolink:NamedThing	nucleoplasmic periphery of the nuclear pore complex	Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex.	got7fsn_ti	associated with the nuclear pore	https://github.com/geneontology/go-ontology/issues/21774					sl	2015-08-19T18:26:26Z						cellular_component											owl:Class	
GO:0110114	biolink:NamedThing	negative regulation of lipid transporter activity	Any process that decreases the frequency, rate, or extent of lipid transporter activity.	got7fsn_ti							kmv	2018-07-06T19:21:44Z						biological_process											owl:Class	
GO:0060324	biolink:NamedThing	face development	The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.	got7fsn_ti														biological_process											owl:Class	
GO:0010073	biolink:NamedThing	meristem maintenance	Any process involved in maintaining the identity, size and shape of a meristem.	got7fsn_ti														biological_process											owl:Class	
GO:0015146	biolink:NamedThing	pentose transmembrane transporter activity	Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms.	got7fsn_ti														molecular_function											owl:Class	
GO:0015750	biolink:NamedThing	pentose transmembrane transport	The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule.	got7fsn_ti	pentose transport													biological_process											owl:Class	
GO:0000755	biolink:NamedThing	cytogamy	During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	zygote formation										GO:0030462|GO:0000218			biological_process											owl:Class	
GO:0021980	biolink:NamedThing	subpallium cell migration	The orderly movement of cells from one site to another in the subpallium.	got7fsn_ti														biological_process											owl:Class	
GO:1903667	biolink:NamedThing	regulation of chemorepellent activity	Any process that modulates the frequency, rate or extent of chemorepellent activity.	got7fsn_ti	regulation of chemorepellant activity						pf	2014-11-26T23:58:33Z						biological_process											owl:Class	
GO:0060133	biolink:NamedThing	somatotropin secreting cell development	The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.	got7fsn_ti	somatotrophin secreting cell development|somatotrope development|growth hormone secreting cell development|somatrophic cell development|somatotropic cell development|somatotroph development													biological_process											owl:Class	
GO:0032937	biolink:NamedThing	SREBP-SCAP-Insig complex	A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0098841	biolink:NamedThing	protein localization to cell division site after cytokinesis	A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis.	got7fsn_ti														biological_process											owl:Class	
GO:0060132	biolink:NamedThing	prolactin secreting cell development	The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.	got7fsn_ti	lactotroph development|mammotrope development|mammotroph development|epsilon-acidophil development|lactotropic cell development|lactotrope development|mammotropic cell development|mammotrophic cell development													biological_process											owl:Class	
GO:0060127	biolink:NamedThing	prolactin secreting cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.	got7fsn_ti	epsilon-acidophil differentiation|mammotrope differentiation|mammotroph differentiation|mammotropic cell differentiation|lactotropic cell differentiation|lactotroph differentiation|lactotrope differentiation|mammotrophic cell differentiation													biological_process											owl:Class	
GO:0036080	biolink:NamedThing	purine nucleotide-sugar transmembrane transporter activity	Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti							bf	2011-12-19T03:29:06Z						molecular_function											owl:Class	
GO:0090480	biolink:NamedThing	purine nucleotide-sugar transmembrane transport	The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti	purine nucleotide-sugar membrane transport|purine nucleotide-sugar transport				Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2011-12-19T03:22:58Z			GO:0036079			biological_process											owl:Class	
GO:1903913	biolink:NamedThing	regulation of fusion of virus membrane with host plasma membrane	Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane.	got7fsn_ti	regulation of viral envelope fusion|regulation of viral envelope fusion with host cell membrane|regulation of viral-cell fusion molecule activity|regulation of viral envelope fusion with host membrane|regulation of viral penetration via membrane fusion|regulation of viral entry into host cell via membrane fusion with the plasma membrane|regulation of viral envelope fusion with host plasma membrane						als	2015-02-09T11:13:19Z						biological_process											owl:Class	
GO:0106084	biolink:NamedThing	mitotic nuclear membrane microtubule tethering complex	A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane.	got7fsn_ti	nuclear membrane mitotic spindle pole body tethering complex|Mps2-Bbp1-Spc29 complex	https://github.com/geneontology/go-ontology/issues/14829			In S. cerevisae Mps2-Bpb1 is the membrane anchor sub complex and Spc29 is the spindle pole body linker molecule.		hjd	2018-01-05T19:55:37Z						cellular_component											owl:Class	
GO:1990608	biolink:NamedThing	mitotic spindle pole body localization	A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location.	got7fsn_ti	spindle pole body localization to nuclear envelope|spindle pole body docking|establishment and maintenance of spindle pole body localization|establishment of spindle pole body localization|establishment of spindle pole body localisation|spindle pole body localization in nuclear envelope|spindle pole body localisation in nuclear envelope|mitotic spindle pole body localization to nuclear envelope|spindle pole body positioning	https://github.com/geneontology/go-ontology/issues/19149					vw	2009-05-06T02:35:32Z			GO:0070632|GO:0071789			biological_process											owl:Class	
GO:0034971	biolink:NamedThing	histone H3-R17 methylation	The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.	got7fsn_ti	histone H3 R17 methylation|histone lysine H3 R17 methylation|histone H3R17me													biological_process											owl:Class	
GO:1990805	biolink:NamedThing	central cylinder	A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules.	got7fsn_ti							kmv	2015-07-17T17:48:17Z						cellular_component											owl:Class	
GO:0110158	biolink:NamedThing	calpain complex	A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate.	got7fsn_ti	mu-calpain|M-calpain						kmv	2019-07-15T18:30:51Z						cellular_component											owl:Class	
GO:0008028	biolink:NamedThing	monocarboxylic acid transmembrane transporter activity	Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.	got7fsn_ti	prostaglandin/thromboxane transporter activity|monocarboxylate carrier										GO:0008505	Reactome:R-HSA-5624211|Reactome:R-HSA-433698|Reactome:R-HSA-9645220|Reactome:R-HSA-429749		molecular_function											owl:Class	
GO:0015718	biolink:NamedThing	monocarboxylic acid transport	The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0061394	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.	got7fsn_ti							dph	2011-12-14T08:48:36Z						biological_process											owl:Class	
GO:0071243	biolink:NamedThing	cellular response to arsenic-containing substance	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.	got7fsn_ti	cellular response to arsenic						mah	2009-12-03T02:41:05Z						biological_process											owl:Class	
GO:0008519	biolink:NamedThing	ammonium transmembrane transporter activity	Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.	got7fsn_ti	ammonia transmembrane transporter activity										GO:0051739	Reactome:R-HSA-444416|Reactome:R-HSA-444393|RHEA:28747|Reactome:R-HSA-444419|Reactome:R-HSA-446278|Reactome:R-HSA-5623051|Reactome:R-HSA-446277		molecular_function											owl:Class	
GO:0072488	biolink:NamedThing	ammonium transmembrane transport	The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.	got7fsn_ti	ammonium membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-12-10T10:29:57Z						biological_process											owl:Class	
GO:0060934	biolink:NamedThing	His-Purkinje system cell fate commitment	The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.	got7fsn_ti							dph	2009-09-29T01:17:00Z						biological_process											owl:Class	
GO:0008056	biolink:NamedThing	ocellus development	The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.	got7fsn_ti														biological_process											owl:Class	
GO:0015192	biolink:NamedThing	L-phenylalanine transmembrane transporter activity	Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.	got7fsn_ti	L-phenylalanine transporter activity|L-phenylalanine permease activity													molecular_function											owl:Class	
GO:0015823	biolink:NamedThing	phenylalanine transport	The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-phenylalanine transport													biological_process											owl:Class	
GO:0021693	biolink:NamedThing	cerebellar Purkinje cell layer structural organization	The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	got7fsn_ti	cerebellar Purkinje cell layer structural organisation													biological_process											owl:Class	
GO:0006624	biolink:NamedThing	vacuolar protein processing	Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.	got7fsn_ti	vacuolar protein maturation|vacuolar proteolysis													biological_process											owl:Class	
GO:0021750	biolink:NamedThing	vestibular nucleus development	The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0021727	biolink:NamedThing	intermediate reticular formation development	The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure.	got7fsn_ti	intermediate reticular nucleus development													biological_process											owl:Class	
GO:0021723	biolink:NamedThing	medullary reticular formation development	The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.	got7fsn_ti	rhombencephalic reticular formation development													biological_process											owl:Class	
GO:0022623	biolink:NamedThing	proteasome-activating nucleotidase complex	A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner.	got7fsn_ti	PAN													cellular_component											owl:Class	
GO:0106164	biolink:NamedThing	positive regulation of exonucleolytic catabolism of deadenylated mRNA	Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.	got7fsn_ti							hjd	2019-01-15T15:39:19Z						biological_process											owl:Class	
GO:0045696	biolink:NamedThing	positive regulation of embryo sac egg cell differentiation	Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation.	got7fsn_ti	activation of female gametophyte egg cell differentiation|up-regulation of female gametophyte egg cell differentiation|up regulation of female gametophyte egg cell differentiation|stimulation of female gametophyte egg cell differentiation|upregulation of female gametophyte egg cell differentiation|positive regulation of female gametophyte egg cell differentiation													biological_process											owl:Class	
GO:0098772	biolink:NamedThing	molecular function regulator	A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20862|https://github.com/geneontology/go-ontology/issues/20854												molecular_function											owl:Class	
GO:0061589	biolink:NamedThing	calcium activated phosphatidylserine scrambling	The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.	got7fsn_ti							dph	2014-02-05T15:17:21Z						biological_process											owl:Class	
GO:0061588	biolink:NamedThing	calcium activated phospholipid scrambling	The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.	got7fsn_ti							dph	2014-02-05T15:14:34Z						biological_process											owl:Class	
GO:0050811	biolink:NamedThing	GABA receptor binding	Binding to a gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.	got7fsn_ti	4-aminobutanoate receptor binding|4-aminobutyrate receptor binding|diazepam binding inhibitor activity|gamma-aminobutyric acid receptor binding													molecular_function											owl:Class	
GO:0019789	biolink:NamedThing	SUMO transferase activity	Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.	got7fsn_ti	SUMO conjugating enzyme activity|SMT3 conjugating enzyme										GO:0019949|GO:0016930	Reactome:R-HSA-4085994|Reactome:R-HSA-4551616|Reactome:R-HSA-4641362|Reactome:R-HSA-4085992|Reactome:R-HSA-4551768|Reactome:R-HSA-4615900|Reactome:R-HSA-4551727|Reactome:R-HSA-4655431|Reactome:R-HSA-4086083|Reactome:R-HSA-4551683|Reactome:R-HSA-4341016|Reactome:R-HSA-3000411|Reactome:R-HSA-3900047|Reactome:R-HSA-4615839|Reactome:R-HSA-4085331|Reactome:R-HSA-3000383|Reactome:R-HSA-4655440|Reactome:R-HSA-4655355|Reactome:R-HSA-4090408|Reactome:R-HSA-4090281|Reactome:R-HSA-4085372|Reactome:R-HSA-2993769|Reactome:R-HSA-4570485|Reactome:R-HSA-4717521|Reactome:R-HSA-4719436|Reactome:R-HSA-4546387|Reactome:R-HSA-3968414|Reactome:R-HSA-5684052|Reactome:R-HSA-4086059|Reactome:R-HSA-3927824|Reactome:R-HSA-3232162|Reactome:R-HSA-4719423|Reactome:R-HSA-4086036|Reactome:R-HSA-3000399|Reactome:R-HSA-2993790|Reactome:R-HSA-4570493|Reactome:R-HSA-4085296|Reactome:R-HSA-4719413|Reactome:R-HSA-4568914|Reactome:R-HSA-2997616|Reactome:R-HSA-6804468|Reactome:R-HSA-4641345|Reactome:R-HSA-3000434|Reactome:R-HSA-4090288|Reactome:R-HSA-4551661|Reactome:R-HSA-4615872|Reactome:R-HSA-3108212|Reactome:R-HSA-4551649|Reactome:R-HSA-2997706|Reactome:R-HSA-3900070|Reactome:R-HSA-4615987|Reactome:R-HSA-3968362|Reactome:R-HSA-4570553|Reactome:R-HSA-4090390|Reactome:R-HSA-4341025|Reactome:R-HSA-3108203|Reactome:R-HSA-5682607|Reactome:R-HSA-4551679|Reactome:R-HSA-4755494|Reactome:R-HSA-3900177|Reactome:R-HSA-4085347|Reactome:R-HSA-4720432|Reactome:R-HSA-5228521|Reactome:R-HSA-3234081|Reactome:R-HSA-4341072|Reactome:R-HSA-4085318|Reactome:R-HSA-3927959|Reactome:R-HSA-4570463|Reactome:R-HSA-4615889|Reactome:R-HSA-3234084|Reactome:R-HSA-3247493|Reactome:R-HSA-4551724|Reactome:R-HSA-3234094|Reactome:R-HSA-4717461|Reactome:R-HSA-4568848|Reactome:R-HSA-3000433|Reactome:R-HSA-4615873|Reactome:R-HSA-4085350|Reactome:R-HSA-5228508|Reactome:R-HSA-4615905|Reactome:R-HSA-4568863|Reactome:R-HSA-4551648|Reactome:R-HSA-3000449|Reactome:R-HSA-3927886|Reactome:R-HSA-3903017|Reactome:R-HSA-4570499|Reactome:R-HSA-4616015|Reactome:R-HSA-4570554|Reactome:R-HSA-4090284|Reactome:R-HSA-2997709|Reactome:R-HSA-4719424|Reactome:R-HSA-6790454|Reactome:R-HSA-4341073|Reactome:R-HSA-3108209|Reactome:R-HSA-4755526|Reactome:R-HSA-4568846|Reactome:R-HSA-3465545|Reactome:R-HSA-4641342|Reactome:R-HSA-4551655|Reactome:R-HSA-4341070|Reactome:R-HSA-4641350|Reactome:R-HSA-3782535|Reactome:R-HSA-4546386|Reactome:R-HSA-3296126|Reactome:R-HSA-4086088|Reactome:R-HSA-3899291|Reactome:R-HSA-4551604|Reactome:R-HSA-4546385|Reactome:R-HSA-4551738|Reactome:R-HSA-2993780|Reactome:R-HSA-4615933|Reactome:R-HSA-4551721|Reactome:R-HSA-4755411|Reactome:R-HSA-4755478|Reactome:R-HSA-6804485|Reactome:R-HSA-3000348|Reactome:R-HSA-4570496|Reactome:R-HSA-4570489|Reactome:R-HSA-4755479|Reactome:R-HSA-5228525|Reactome:R-HSA-4655374|Reactome:R-HSA-4719447|Reactome:R-HSA-2997723|Reactome:R-HSA-4720446|Reactome:R-HSA-5228523|Reactome:R-HSA-4570467|Reactome:R-HSA-4341048|Reactome:R-HSA-4615910|Reactome:R-HSA-3900194|Reactome:R-HSA-4656914|Reactome:R-HSA-4755536|Reactome:R-HSA-4570528|Reactome:R-HSA-8956365|Reactome:R-HSA-4719448		molecular_function											owl:Class	
GO:0106230	biolink:NamedThing	protein depropionylation	The removal of a propionyl group from a residue in a peptide or protein.	got7fsn_ti							hjd	2019-10-17T19:10:50Z						biological_process											owl:Class	
GO:0008517	biolink:NamedThing	folic acid transmembrane transporter activity	Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.	got7fsn_ti	folate transmembrane transporter activity|vitamin M transporter activity|folate transporter activity|vitamin B9 transporter activity|folic acid transporter activity											Reactome:R-HSA-200652|Reactome:R-HSA-200680|Reactome:R-HSA-200720|Reactome:R-HSA-200729|Reactome:R-HSA-200646		molecular_function											owl:Class	
GO:0071699	biolink:NamedThing	olfactory placode morphogenesis	The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.	got7fsn_ti							mah	2010-03-02T12:45:45Z						biological_process											owl:Class	
GO:0044206	biolink:NamedThing	UMP salvage	Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis.	got7fsn_ti	UMP biosynthetic process via nucleoside salvage pathway|UMP biosynthesis via nucleoside salvage pathway						jl	2009-10-21T11:32:33Z						biological_process											owl:Class	
GO:0004163	biolink:NamedThing	diphosphomevalonate decarboxylase activity	Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate.	got7fsn_ti	mevalonate pyrophosphate decarboxylase activity|pyrophosphomevalonic acid decarboxylase activity|mevalonate diphosphate decarboxylase activity|ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)|pyrophosphomevalonate decarboxylase activity|mevalonate-5-pyrophosphate decarboxylase activity|mevalonate 5-diphosphate decarboxylase activity|ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)|5-pyrophosphomevalonate decarboxylase activity											KEGG_REACTION:R01121|EC:4.1.1.33|MetaCyc:DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN|Reactome:R-HSA-191414|RHEA:23732		molecular_function											owl:Class	
GO:0086021	biolink:NamedThing	SA node cell to atrial cardiac muscle cell communication by electrical coupling	The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti	SAN cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|SA node cardiac muscle cell to atrial cardiac muscle cell communication by electrical coupling|SA node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|sinoatrial node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|sinus node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling						tb	2011-11-10T09:20:39Z						biological_process											owl:Class	
GO:0019616	biolink:NamedThing	catechol catabolic process, meta-cleavage	The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom.	got7fsn_ti	catechol breakdown, meta-cleavage|catechol degradation, meta-cleavage											MetaCyc:P183-PWY		biological_process											owl:Class	
GO:0043663	biolink:NamedThing	host bacteroid-containing symbiosome	A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0043658	biolink:NamedThing	host symbiosome	A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0002112	biolink:NamedThing	interleukin-33 receptor binding	Binding to an interleukin-33 receptor.	got7fsn_ti	IL-33|interleukin-33 receptor ligand													molecular_function											owl:Class	
GO:0047473	biolink:NamedThing	D-alanine [D-alanyl carrier protein] ligase activity	Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate.	got7fsn_ti	D-alanine:poly(phosphoribitol) ligase (AMP-forming)|D-alanine-activating enzyme activity|D-alanine-D-alanyl carrier protein ligase activity|D-alanine-poly(phosphoribitol) ligase activity	https://github.com/geneontology/go-ontology/issues/14237										MetaCyc:6.2.1.M5-RXN|EC:6.2.1.-		molecular_function											owl:Class	
GO:0050835	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide.	got7fsn_ti												RESID:AA0356		biological_process											owl:Class	
GO:0034397	biolink:NamedThing	telomere localization	Any process in which a telomere is transported to, and/or maintained in, a specific location.	got7fsn_ti	telomere localisation													biological_process											owl:Class	
GO:0050000	biolink:NamedThing	chromosome localization	Any process in which a chromosome is transported to, or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of chromosome localization|chromosome localisation|establishment and maintenance of chromosome position													biological_process											owl:Class	
GO:0042052	biolink:NamedThing	rhabdomere development	The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.	got7fsn_ti	rhabdomere organization													biological_process											owl:Class	
GO:0035450	biolink:NamedThing	extrinsic component of lumenal side of plastid thylakoid membrane	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to lumenal leaflet of plastid thylakoid membrane|extrinsic to lumenal side of plastid thylakoid membrane|peripheral to lumenal side of plastid thylakoid membrane						bf	2010-04-16T10:17:25Z						cellular_component											owl:Class	
GO:0006361	biolink:NamedThing	transcription initiation from RNA polymerase I promoter	Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an RNA polymerase I promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.	got7fsn_ti	transcription initiation from Pol I promoter|transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript				Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.		krc	2011-08-15T03:45:49Z			GO:0001180			biological_process											owl:Class	
GO:0045241	biolink:NamedThing	cytosolic alpha-ketoglutarate dehydrogenase complex	Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity.	got7fsn_ti	2-oxoglutarate dehydrogenase complex													cellular_component											owl:Class	
GO:0045240	biolink:NamedThing	dihydrolipoyl dehydrogenase complex	A protein complex that possesses alpha-ketoglutarate dehydrogenase activity.	got7fsn_ti	2-oxoglutarate dehydrogenase complex|alpha-ketoglutarate dehydrogenase complex													cellular_component											owl:Class	
GO:0050299	biolink:NamedThing	streptomycin 3''-kinase activity	Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3''-phosphate.	got7fsn_ti	ATP:streptomycin 3''-phosphotransferase activity|streptomycin 3''-kinase (phosphorylating)|streptomycin 3''-phosphotransferase activity											EC:2.7.1.87|RHEA:18377|KEGG_REACTION:R02227|MetaCyc:STREPTOMYCIN-3-KINASE-RXN		molecular_function											owl:Class	
GO:0075220	biolink:NamedThing	positive regulation of zoospore encystment on host	Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0010077	biolink:NamedThing	maintenance of inflorescence meristem identity	The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0050034	biolink:NamedThing	L-rhamnose 1-dehydrogenase activity	Catalysis of the reaction: L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + H(+) + NADH.	got7fsn_ti	L-rhamnofuranose:NAD+ 1-oxidoreductase activity											KEGG_REACTION:R03942|EC:1.1.1.173|MetaCyc:L-RHAMNOSE-1-DEHYDROGENASE-RXN|RHEA:12649		molecular_function											owl:Class	
GO:0008886	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(2)O + NADP(+) = 3-phospho-D-glycerate + 2 H(+) + NADPH.	got7fsn_ti	dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate)|D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase activity|nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde-3-phosphate dehydrogenase (NADP)|glyceraldehyde phosphate dehydrogenase (NADP)|triosephosphate dehydrogenase activity|glyceraldehyde 3-phosphate dehydrogenase (NADP)|NADP-glyceraldehyde phosphate dehydrogenase|NADP-glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde-3-phosphate:NADP reductase activity											MetaCyc:1.2.1.9-RXN|RHEA:14669|KEGG_REACTION:R01058|EC:1.2.1.9		molecular_function											owl:Class	
GO:0008344	biolink:NamedThing	adult locomotory behavior	Locomotory behavior in a fully developed and mature organism.	got7fsn_ti	adult locomotory behaviour				See also the biological process term 'locomotory behavior ; GO:0007626'.									biological_process											owl:Class	
GO:0140078	biolink:NamedThing	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate.	got7fsn_ti	DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity|DNA-(apurinic or apyrimidinic site) lyase activity|AP endonuclease class I activity|AP site-DNA 5'-phosphomonoester-lyase activity|class I DNA-(apurinic or apyrimidinic site) lyase activity						pg	2017-07-24T11:33:34Z				MetaCyc:4.2.99.18-RXN|EC:4.2.99.18		molecular_function											owl:Class	
GO:0001858	biolink:NamedThing	complement component iC3b receptor activity	Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0031894	biolink:NamedThing	V1A vasopressin receptor binding	Binding to a V1A vasopressin receptor.	got7fsn_ti	V1A vasopressin receptor ligand													molecular_function											owl:Class	
GO:0031893	biolink:NamedThing	vasopressin receptor binding	Binding to a vasopressin receptor.	got7fsn_ti	vasopressin receptor ligand													molecular_function											owl:Class	
GO:0070385	biolink:NamedThing	egasyn-beta-glucuronidase complex	A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum.	got7fsn_ti														cellular_component											owl:Class	
GO:0000373	biolink:NamedThing	Group II intron splicing	The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat.	got7fsn_ti	mRNA splicing				Note that Group II introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; and mRNA of bacteria.									biological_process											owl:Class	
GO:0000377	biolink:NamedThing	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.	got7fsn_ti	lariat RNA formation|lariat RNA biosynthesis													biological_process											owl:Class	
GO:0004042	biolink:NamedThing	acetyl-CoA:L-glutamate N-acetyltransferase activity	Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+).	got7fsn_ti	amino acid acetyltransferase activity|N-acetylglutamate synthase activity|acetylglutamate acetylglutamate synthetase activity|amino-acid N-acetyltransferase activity|AGAS											KEGG_REACTION:R00259|MetaCyc:N-ACETYLTRANSFER-RXN|Reactome:R-HSA-70542|RHEA:24292|EC:2.3.1.1		molecular_function											owl:Class	
GO:1900614	biolink:NamedThing	F-9775B biosynthetic process	The chemical reactions and pathways resulting in the formation of F-9775B.	got7fsn_ti	F-9775B biosynthesis|F-9775B formation|F-9775B synthesis|F-9775B anabolism						di	2012-05-15T07:03:32Z						biological_process											owl:Class	
GO:0030930	biolink:NamedThing	homotetrameric ADPG pyrophosphorylase complex	A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity. Examples of this component are found in Bacterial species.	got7fsn_ti														cellular_component											owl:Class	
GO:0047482	biolink:NamedThing	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity	Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine.	got7fsn_ti	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity|L-lysine-adding enzyme activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)|UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity|uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity|MurE synthetase activity											KEGG_REACTION:R02786|RHEA:17969|EC:6.3.2.7|MetaCyc:6.3.2.7-RXN		molecular_function											owl:Class	
GO:0060497	biolink:NamedThing	mesenchymal-endodermal cell signaling	Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.	got7fsn_ti	mesenchymal-endodermal cell signalling													biological_process											owl:Class	
GO:0110152	biolink:NamedThing	RNA NAD-cap (NAD-forming) hydrolase activity	Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+).	got7fsn_ti					This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.		kmv	2019-07-08T15:55:11Z				RHEA:60880		molecular_function											owl:Class	
GO:0090586	biolink:NamedThing	protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0045512	biolink:NamedThing	interleukin-26 binding	Binding to interleukin-26.	got7fsn_ti	IL-26 binding													molecular_function											owl:Class	
GO:0032631	biolink:NamedThing	interleukin-27 production	The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-27 secretion|interleukin-27 formation|interleukin-27 biosynthetic process|IL-27 production|interleukin-27 synthesis										GO:0045527|GO:0072625			biological_process											owl:Class	
GO:0004814	biolink:NamedThing	arginine-tRNA ligase activity	Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).	got7fsn_ti	arginyl-transfer ribonucleate synthetase activity|L-arginine:tRNAArg ligase (AMP-forming)|arginyl transfer ribonucleic acid synthetase activity|arginyl-tRNA synthetase activity|arginine translase activity|arginyl-transfer RNA synthetase activity|arginine-tRNA synthetase activity											MetaCyc:ARGININE--TRNA-LIGASE-RXN|RHEA:20301|Reactome:R-HSA-379993|Reactome:R-HSA-380224|EC:6.1.1.19		molecular_function											owl:Class	
GO:0035103	biolink:NamedThing	sterol regulatory element binding protein cleavage	The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids.	got7fsn_ti	sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway|SREBP cleavage|sterol depletion response, SREBP cleavage										GO:0006992			biological_process											owl:Class	
GO:0004504	biolink:NamedThing	peptidylglycine monooxygenase activity	Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.	got7fsn_ti	peptidylglycine alpha-hydroxylase activity|peptidylglycine alpha-amidating monooxygenase activity|peptidyl alpha-amidating enzyme activity|PAM-A|peptide-alpha-amide synthetase activity|peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)|synthase, peptide alpha-amide|peptide alpha-amide synthase activity|peptidylglycine 2-hydroxylase activity|PAM-B|PAM activity|peptide alpha-amidating enzyme											EC:1.14.17.3|RHEA:21452|MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0009356	biolink:NamedThing	aminodeoxychorismate synthase complex	A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity.	got7fsn_ti	ADC synthase complex|p-aminobenzoate synthetase complex|4-amino-4-deoxychorismate synthase complex													cellular_component											owl:Class	
GO:0090161	biolink:NamedThing	Golgi ribbon formation	The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.	got7fsn_ti							tb	2009-12-08T08:38:14Z						biological_process											owl:Class	
GO:0007030	biolink:NamedThing	Golgi organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.	got7fsn_ti	Golgi organisation|Golgi organization and biogenesis													biological_process											owl:Class	
GO:2000539	biolink:NamedThing	regulation of protein geranylgeranylation	Any process that modulates the frequency, rate or extent of protein geranylgeranylation.	got7fsn_ti	regulation of protein amino acid geranylgeranylation|regulation of C-terminal protein geranylgeranylation						tb	2011-03-29T06:23:05Z						biological_process											owl:Class	
GO:0006638	biolink:NamedThing	neutral lipid metabolic process	The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity.	got7fsn_ti	neutral lipid metabolism													biological_process											owl:Class	
GO:0000722	biolink:NamedThing	telomere maintenance via recombination	Any recombinational process that contributes to the maintenance of proper telomeric length.	got7fsn_ti	telomerase-independent telomere maintenance													biological_process											owl:Class	
GO:0060933	biolink:NamedThing	His-Purkinje system cell development	The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.	got7fsn_ti							dph	2009-09-29T01:15:02Z						biological_process											owl:Class	
GO:0018394	biolink:NamedThing	peptidyl-lysine acetylation	The acetylation of peptidyl-lysine.	got7fsn_ti														biological_process											owl:Class	
GO:0004357	biolink:NamedThing	glutamate-cysteine ligase activity	Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate.	got7fsn_ti	L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity|gamma-glutamylcysteine synthetase activity|gamma-glutamyl-L-cysteine synthetase activity|gamma-glutamylcysteinyl synthetase activity											KEGG_REACTION:R00894|Reactome:R-HSA-5602892|MetaCyc:GLUTCYSLIG-RXN|Reactome:R-HSA-174367|EC:6.3.2.2|RHEA:13285		molecular_function											owl:Class	
GO:0101021	biolink:NamedThing	estrogen 2-hydroxylase activity	Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O.	got7fsn_ti	oestrogen 2-hydroxylase activity													molecular_function											owl:Class	
GO:0035893	biolink:NamedThing	negative regulation of platelet aggregation in other organism	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism.	got7fsn_ti	inhibition of platelet aggregation in other organism|down-regulation of platelet aggregation in other organism|suppression of platelet aggregation in other organism|downregulation of platelet aggregation in other organism						bf	2011-06-15T02:24:43Z						biological_process											owl:Class	
GO:0019234	biolink:NamedThing	sensory perception of fast pain	The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds.	got7fsn_ti														biological_process											owl:Class	
GO:0043688	biolink:NamedThing	conversion of aspartyl-tRNA to asparaginyl-tRNA	The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA.	got7fsn_ti					Note that this process has been observed in some archaeal and bacterial species.									biological_process											owl:Class	
GO:0044507	biolink:NamedThing	positive regulation of receptor activity in other organism	A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism.	got7fsn_ti							jl	2012-02-23T04:31:52Z						biological_process											owl:Class	
GO:0034685	biolink:NamedThing	integrin alphav-beta6 complex	An integrin complex that comprises one alphav subunit and one beta6 subunit.	got7fsn_ti	ITGAV-ITGB6 complex|alphav-beta6 integrin complex													cellular_component											owl:Class	
GO:0050370	biolink:NamedThing	tyrosine N-monooxygenase activity	Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O.	got7fsn_ti	CYP79A1 activity|L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating)|tyrosine N-hydroxylase activity											RHEA:22464|MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0047171	biolink:NamedThing	glucarolactone O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA.	got7fsn_ti	sinapoyl-CoA:glucarolactone O-(hydroxycinnamoyl)transferase activity											MetaCyc:2.3.1.132-RXN|RHEA:14261|EC:2.3.1.132		molecular_function											owl:Class	
GO:0050172	biolink:NamedThing	phenylalanine 2-monooxygenase activity	Catalysis of the reaction: L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O.	got7fsn_ti	l-phenylalanine oxidase (deaminating and decarboxylating) activity|phenylalanine (deaminating, decarboxylating)oxidase activity|L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)|phenylalanine (deaminating, decarboxylating) oxidase activity|L-phenylalanine oxidase (deaminating and decarboxylating)											MetaCyc:PHENYLALANINE-2-MONOOXYGENASE-RXN|RHEA:10712|KEGG_REACTION:R00690|EC:1.13.12.9		molecular_function											owl:Class	
GO:1990832	biolink:NamedThing	slow axonal transport	The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition.	got7fsn_ti							sl	2015-08-21T17:27:32Z						biological_process											owl:Class	
GO:0008088	biolink:NamedThing	axo-dendritic transport	The directed movement of organelles or molecules along microtubules in neuron projections.	got7fsn_ti	axoplasmic transport|axonal transport|axon cargo transport											Wikipedia:Axoplasmic_transport		biological_process											owl:Class	
GO:0070917	biolink:NamedThing	inositol phosphoceramide synthase regulator activity	Binds to and modulates the activity of inositol phosphoceramide synthase.	got7fsn_ti	IPC synthase regulator activity				See also the molecular function term 'histone acetyltransferase activity ; GO:0004402'.		mah	2009-09-10T05:27:06Z						molecular_function											owl:Class	
GO:0047620	biolink:NamedThing	acylglycerol kinase activity	Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.	got7fsn_ti	monoacylglycerol kinase activity|MGK|monoglyceride kinase activity|monoglyceride phosphokinase activity|monoacylglycerol kinase (phosphorylating)|ATP:acylglycerol 3-phosphotransferase activity|sn-2-monoacylglycerol kinase activity											Reactome:R-HSA-5696074|RHEA:19293|EC:2.7.1.94|MetaCyc:ACYLGLYCEROL-KINASE-RXN		molecular_function											owl:Class	
GO:0103106	biolink:NamedThing	brassinolide 23-O-glucosyltransferase activity	Catalysis of the reaction: brassinolide + UDP-alpha-D-glucose <=> brassinolide-23-O-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXNQT-4397		molecular_function											owl:Class	
GO:1990947	biolink:NamedThing	exit from meiosis	Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half.	got7fsn_ti	meiotic exit						vw	2016-04-21T14:14:15Z						biological_process											owl:Class	
GO:0050394	biolink:NamedThing	viomycin kinase activity	Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin.	got7fsn_ti	viomycin phosphotransferase activity|capreomycin phosphotransferase activity|ATP:viomycin O-phosphotransferase activity											EC:2.7.1.103|RHEA:20509|MetaCyc:VIOMYCIN-KINASE-RXN		molecular_function											owl:Class	
GO:0008836	biolink:NamedThing	diaminopimelate decarboxylase activity	Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2).	got7fsn_ti	DAP-decarboxylase activity|meso-2,6-diaminoheptanedioate carboxy-lyase activity|DAP decarboxylase activity|meso-2,6-diaminoheptanedioate carboxy-lyase (L-lysine-forming)|diaminopimelic acid decarboxylase activity|meso-diaminopimelate decarboxylase activity											MetaCyc:DIAMINOPIMDECARB-RXN|EC:4.1.1.20|KEGG_REACTION:R00451|RHEA:15101		molecular_function											owl:Class	
GO:0015047	biolink:NamedThing	NADPH-cytochrome-c2 reductase activity	Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2.	got7fsn_ti	cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide phosphate, NADPH)|NADPH:ferricytochrome-c2 oxidoreductase activity|reductase, cytochrome c2 (reduced nicotinamide adenine dinucleotide phosphate)											MetaCyc:NADPH--CYTOCHROME-C2-REDUCTASE-RXN|EC:1.6.2.5|RHEA:15237		molecular_function											owl:Class	
GO:0033411	biolink:NamedThing	UAA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UAA codon.	got7fsn_ti	TAA codon-amino acid adaptor activity				Note that in the standard genetic code, TAA is a stop codon (ochre) and is not normally read by a tRNA.									molecular_function											owl:Class	
GO:0009293	biolink:NamedThing	transduction	The transfer of genetic information to a bacterium from a bacteriophage or between bacterial or yeast cells mediated by a phage vector.	got7fsn_ti												Wikipedia:Transduction_(genetics)		biological_process											owl:Class	
GO:0009292	biolink:NamedThing	genetic transfer	In the absence of a sexual life cycle, the process involved in the introduction of genetic information to create a genetically different individual.	got7fsn_ti	genetic exchange				GO:0009292 should not be used for annotation of phage lysogeny (integration of the bacteriophage nucleic acid into the host bacterium's genome).									biological_process											owl:Class	
GO:0070069	biolink:NamedThing	cytochrome complex	A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.	got7fsn_ti														cellular_component											owl:Class	
GO:0080078	biolink:NamedThing	tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule.	got7fsn_ti							dhl	2009-04-14T04:01:25Z						molecular_function											owl:Class	
GO:0099615	biolink:NamedThing	(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity	Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor.	got7fsn_ti	D-2HG-pyruvate transhydrogenase activity|R-2-hydroxyglutarate alpha-pyruvate transhydrogenase activity													molecular_function											owl:Class	
GO:0042352	biolink:NamedThing	GDP-L-fucose salvage	The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30).	got7fsn_ti	GDP-L-fucose biosynthesis, salvage pathway|GDP-L-fucose biosynthetic process, salvage pathway											MetaCyc:PWY-6		biological_process											owl:Class	
GO:0038087	biolink:NamedThing	VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	VEGF/PDGFRalpha signaling pathway|VEGF-activated platelet-derived growth factor receptor-alpha signalling pathway|VEGF-A/PDGFRalpha signaling|vascular endothelial growth factor-activated platelet-derived growth factor receptor-alpha signaling pathway|VEGF-activated PDGFRalpha signalling pathway						bf	2012-02-01T03:08:13Z						biological_process											owl:Class	
GO:0031317	biolink:NamedThing	tripartite ATP-independent periplasmic transporter complex	A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients.	got7fsn_ti	TRAP transporter complex|TRAP-T transporter complex													cellular_component											owl:Class	
GO:0072627	biolink:NamedThing	interleukin-28A production	The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interferon lambda 2 production|IL-28A production|IL28A production|interleukin-28A secretion				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072628			biological_process											owl:Class	
GO:0034343	biolink:NamedThing	type III interferon production	The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	type III interferon secretion|type III IFN production				Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. This term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072644			biological_process											owl:Class	
GO:0035978	biolink:NamedThing	histone H2A-S139 phosphorylation	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 139 of the histone.	got7fsn_ti	histone H2A.x phosphorylation at S139				Residue 1 of histone H2AX is taken as the first residue following removal of the initiating Methionine (Met).		bf	2011-08-22T11:34:09Z						biological_process											owl:Class	
GO:1990164	biolink:NamedThing	histone H2A phosphorylation	The modification of histone H2A by the addition of a phosphate group.	got7fsn_ti							mah	2013-08-08T11:13:25Z						biological_process											owl:Class	
GO:0080081	biolink:NamedThing	4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity	Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside.	got7fsn_ti							dhl	2009-04-14T04:09:06Z						molecular_function											owl:Class	
GO:0097348	biolink:NamedThing	host cell endocytic vesicle membrane	The lipid bilayer surrounding a host cell endocytic vesicle.	got7fsn_ti							pr	2012-06-25T10:31:34Z						cellular_component											owl:Class	
GO:0044162	biolink:NamedThing	host cell cytoplasmic vesicle membrane	The lipid bilayer surrounding a host cell cytoplasmic vesicle.	got7fsn_ti							jl	2009-08-11T04:24:02Z						cellular_component											owl:Class	
GO:0019647	biolink:NamedThing	formaldehyde assimilation via ribulose monophosphate cycle	The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde.	got7fsn_ti	ribulose monophosphate cycle|formaldehyde assimilation via RuMP cycle											MetaCyc:PWY-1861		biological_process											owl:Class	
GO:0021962	biolink:NamedThing	vestibulospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.	got7fsn_ti														biological_process											owl:Class	
GO:0047925	biolink:NamedThing	geranoyl-CoA carboxylase activity	Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H(+) + phosphate.	got7fsn_ti	geranyl-CoA carboxylase activity|geranoyl-CoA:carbon-dioxide ligase (ADP-forming)|geranoyl coenzyme A carboxylase activity											EC:6.4.1.5|KEGG_REACTION:R03494|UM-BBD_reactionID:r1166|MetaCyc:GERANOYL-COA-CARBOXYLASE-RXN|RHEA:17701		molecular_function											owl:Class	
GO:0031372	biolink:NamedThing	UBC13-MMS2 complex	A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p.	got7fsn_ti														cellular_component											owl:Class	
GO:0031371	biolink:NamedThing	ubiquitin conjugating enzyme complex	Any complex that possesses ubiquitin conjugating enzyme activity.	got7fsn_ti	E2 complex													cellular_component											owl:Class	
GO:0102669	biolink:NamedThing	isoflavone-7-O-glucoside beta-glucosidase activity	Catalysis of the reaction: daidzein 7-O-beta-D-glucoside + H2O <=> daidzein + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-3591		molecular_function											owl:Class	
GO:0034384	biolink:NamedThing	high-density lipoprotein particle clearance	The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti	HDL clearance													biological_process											owl:Class	
GO:0007473	biolink:NamedThing	wing disc proximal/distal pattern formation	The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing.	got7fsn_ti														biological_process											owl:Class	
GO:0007449	biolink:NamedThing	proximal/distal pattern formation, imaginal disc	The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.	got7fsn_ti														biological_process											owl:Class	
GO:0036458	biolink:NamedThing	hepatocyte growth factor binding	Binding to a hepatocyte growth factor.	got7fsn_ti	HGF binding						bf	2013-12-09T14:07:20Z						molecular_function											owl:Class	
GO:0002537	biolink:NamedThing	nitric oxide production involved in inflammatory response	The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	production of nitric oxide involved in acute inflammatory response|production of nitric oxide involved in inflammatory response|nitric oxide production involved in acute inflammatory response													biological_process											owl:Class	
GO:0061657	biolink:NamedThing	UFM1 conjugating enzyme activity	Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y -> Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2						dph	2014-11-06T13:35:13Z						molecular_function											owl:Class	
GO:0070856	biolink:NamedThing	myosin VI light chain binding	Binding to a light chain of a myosin VI complex.	got7fsn_ti							mah	2009-08-13T01:46:13Z						molecular_function											owl:Class	
GO:0035770	biolink:NamedThing	ribonucleoprotein granule	A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.	got7fsn_ti	RNP granule|mRNP granule|RNA granule						bf	2011-04-01T10:50:47Z						cellular_component											owl:Class	
GO:0008266	biolink:NamedThing	poly(U) RNA binding	Binding to a sequence of uracil residues in an RNA molecule.	got7fsn_ti	poly(U) binding													molecular_function											owl:Class	
GO:0030698	biolink:NamedThing	5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity	Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria.	got7fsn_ti	RUMT													molecular_function											owl:Class	
GO:0030696	biolink:NamedThing	tRNA (m5U54) methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule.	got7fsn_ti	RUMT				Note that the term name mentions a specific position within a tRNA because no other names have yet arisen for this activity, and because the position is conserved in nearly all tRNAs. The term nevertheless can be used for activities that methylase an analogous residue at a position other than 54, if such is found, and synonyms that mention positions applicable to other tRNAs or species may also be added.									molecular_function											owl:Class	
GO:0008697	biolink:NamedThing	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity	Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate.	got7fsn_ti	5-keto-4-deoxyuronate isomerase activity|4-deoxy-L-threo-5-hexulose uronate isomerase activity|4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity											MetaCyc:5.3.1.17-RXN|KEGG_REACTION:R04383|EC:5.3.1.17|RHEA:23896		molecular_function											owl:Class	
GO:0019751	biolink:NamedThing	polyol metabolic process	The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.	got7fsn_ti	polyhydric alcohol metabolic process|polyol metabolism													biological_process											owl:Class	
GO:0001515	biolink:NamedThing	opioid peptide activity	Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect.	got7fsn_ti														molecular_function											owl:Class	
GO:0044682	biolink:NamedThing	archaeal-specific GTP cyclohydrolase activity	Catalysis of the reaction: GTP + H2O <=> 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + diphosphate +formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+.	got7fsn_ti	Fe(2+)-dependent archaeal-specific GTP cyclohydrolase activity|MptA activity						jl	2012-08-15T11:18:40Z						molecular_function											owl:Class	
GO:0005019	biolink:NamedThing	platelet-derived growth factor beta-receptor activity	Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity.	got7fsn_ti	betaPDGF receptor activity|PDGF beta-receptor activity													molecular_function											owl:Class	
GO:0044097	biolink:NamedThing	secretion by the type IV secretion system	The controlled release of proteins or DNA by a cell, via the type IV secretion system.	got7fsn_ti	secretion via the type IV secretion system						jl	2009-06-09T02:20:34Z						biological_process											owl:Class	
GO:0061144	biolink:NamedThing	alveolar secondary septum development	The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.	got7fsn_ti							dph	2010-05-25T10:43:55Z						biological_process											owl:Class	
GO:0045431	biolink:NamedThing	flavonol synthase activity	Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.	got7fsn_ti	flavonoid 2-oxoglutarate-dependent dioxygenase activity|FLS activity|dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity											EC:1.14.20.6|RHEA:21088		molecular_function											owl:Class	
GO:0008766	biolink:NamedThing	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity	Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine.	got7fsn_ti					Note that EC:6.3.2.15 was deleted from EC as the reaction is performed by UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (EC:6.3.2.10).							EC:6.3.2.10|MetaCyc:UDP-NACMURALGLDAPAALIG-RXN|RHEA:28374		molecular_function											owl:Class	
GO:0030774	biolink:NamedThing	anthranilate N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:anthranilate N-methyltransferase activity|anthranilic acid N-methyltransferase activity											EC:2.1.1.111|MetaCyc:ANTHRANILATE-N-METHYLTRANSFERASE-RXN|RHEA:12180|KEGG_REACTION:R00984		molecular_function											owl:Class	
GO:0045033	biolink:NamedThing	peroxisome inheritance	The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p.	got7fsn_ti					Note that 'vectorial' is used in the definition in the mathematical and physical sense of pertaining to 'a quantity having direction as well as magnitude, especially as determining the position of one point in space relative to another.									biological_process											owl:Class	
GO:1990332	biolink:NamedThing	Ire1 complex	A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript.	got7fsn_ti	ERN1 complex|IRE1 dimer				An example of this is Ire1 in Escherichia coli (P32361) in PMID:18191223 (inferred from direct assay).		bhm	2014-03-17T10:46:58Z						cellular_component											owl:Class	
GO:0052904	biolink:NamedThing	N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 3-acetamidopropanal + H(2)O(2) + putrescine.	got7fsn_ti	polyamine oxidase activity|non-specific polyamine oxidase activity|N(1)-acetylpolyamine oxidase activity											MetaCyc:RXN-9942|EC:1.5.3.13|Reactome:R-HSA-141348|Reactome:R-HSA-141351|KEGG_REACTION:R09074|EC:1.5.3.17|RHEA:25812|MetaCyc:RXN-12091		molecular_function											owl:Class	
GO:0031955	biolink:NamedThing	short-chain fatty acid-CoA ligase activity	Catalysis of the reaction: ATP + a short-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6.	got7fsn_ti	short-chain fatty acid activation|short-chain fatty-acid-CoA ligase activity|short-chain-fatty-acid-CoA ligase activity													molecular_function											owl:Class	
GO:0031944	biolink:NamedThing	negative regulation of glucocorticoid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.	got7fsn_ti	down-regulation of glucocorticoid metabolic process|downregulation of glucocorticoid metabolic process|negative regulation of glucocorticoid metabolism|inhibition of glucocorticoid metabolic process|down regulation of glucocorticoid metabolic process													biological_process											owl:Class	
GO:0042726	biolink:NamedThing	flavin-containing compound metabolic process	The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.	got7fsn_ti	flavin-containing compound metabolism|vitamin B2 and derivative metabolic process|riboflavin and derivative metabolic process|riboflavin and derivative metabolism|vitamin B2 and derivative metabolism													biological_process											owl:Class	
GO:0018416	biolink:NamedThing	nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide	The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.	got7fsn_ti	nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide											RESID:AA0292		biological_process											owl:Class	
GO:0090059	biolink:NamedThing	protoxylem development	The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem.	got7fsn_ti							tb	2009-08-11T03:08:06Z						biological_process											owl:Class	
GO:0099636	biolink:NamedThing	cytoplasmic streaming	The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.	got7fsn_ti												Wikipedia:Cytoplasmic_streaming		biological_process											owl:Class	
GO:0016482	biolink:NamedThing	cytosolic transport	The directed movement of substances or organelles within the cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:0040029	biolink:NamedThing	regulation of gene expression, epigenetic	Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.	got7fsn_ti														biological_process											owl:Class	
GO:0061939	biolink:NamedThing	c-di-GMP signaling	Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.	got7fsn_ti	cyclic di-(3':5')-guanosine monophosphate signaling|3',5'-cyclic di-GMP signaling|cyclic diguanylate signaling|cyclic di-GMP signaling						dph	2017-09-14T18:59:04Z						biological_process											owl:Class	
GO:0048348	biolink:NamedThing	paraxial mesodermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0034018	biolink:NamedThing	ascopyrone tautomerase activity	Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.	got7fsn_ti	ascopyrone intramolecular oxidoreductase activity|ascopyrone isomerase activity|1,5-anhydro-D-glycero-hex-3-en-2-ulose delta3-delta1-isomerase activity|ascopyrone P tautomerase activity|1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase activity|APTM|APM tautomerase activity											MetaCyc:5.3.3.15-RXN|EC:5.3.2.7|RHEA:22568		molecular_function											owl:Class	
GO:0071750	biolink:NamedThing	dimeric IgA immunoglobulin complex	A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	dimeric IgA antibody|dimeric IgA1 antibody				Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0033967	biolink:NamedThing	box C/D RNA metabolic process	The chemical reactions and pathways involving box C/D type small nucleolar RNA.	got7fsn_ti	box C/D sRNA metabolic process|box C/D snoRNA metabolic process	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0061711	biolink:NamedThing	N(6)-L-threonylcarbamoyladenine synthase activity	Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.	got7fsn_ti							dph	2015-06-23T08:34:44Z				EC:2.3.1.234|Reactome:R-HSA-6784494|MetaCyc:RXN-14570|RHEA:37059		molecular_function											owl:Class	
GO:0060855	biolink:NamedThing	venous endothelial cell migration involved in lymph vessel development	The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells.	got7fsn_ti							dph	2009-08-12T12:07:27Z						biological_process											owl:Class	
GO:0043534	biolink:NamedThing	blood vessel endothelial cell migration	The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:2000611	biolink:NamedThing	positive regulation of thyroid hormone generation	Any process that activates or increases the frequency, rate or extent of thyroid hormone generation.	got7fsn_ti							yaf	2011-04-18T10:12:22Z						biological_process											owl:Class	
GO:0042541	biolink:NamedThing	hemoglobin biosynthetic process	The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	got7fsn_ti	hemoglobin anabolism|haemoglobin biosynthesis|hemoglobin biosynthesis|hemoglobin synthesis|haemoglobin biosynthetic process|hemoglobin formation													biological_process											owl:Class	
GO:0007628	biolink:NamedThing	adult walking behavior	The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.	got7fsn_ti	adult walking behaviour													biological_process											owl:Class	
GO:0003089	biolink:NamedThing	positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream.	got7fsn_ti	increased force of heart contraction by circulating epinephrine-norepinephrine|increased force of heart contraction by circulating adrenaline-noradrenaline|positive regulation of heart contraction by circulating adrenaline-noradrenaline|increased force of heart contraction by epinephrine-norepinephrine in the blood stream|positive regulation of heart contraction by circulating epinephrine-norepinephrine													biological_process											owl:Class	
GO:0006833	biolink:NamedThing	water transport	The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0043691	biolink:NamedThing	reverse cholesterol transport	The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0030301	biolink:NamedThing	cholesterol transport	The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0075331	biolink:NamedThing	negative regulation of arbuscule formation for nutrient acquisition from host	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0044147	biolink:NamedThing	negative regulation of formation of structure involved in a symbiotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	got7fsn_ti	negative regulation of development of symbiont during interaction with host|negative regulation of development of symbiont involved in interaction with host	https://github.com/geneontology/go-ontology/issues/20305			This term partially replaces the obsolete term 'negative regulation of growth or development of symbiont during interaction with host ; GO:0075340'.		jl	2009-08-06T02:04:59Z						biological_process											owl:Class	
GO:0102940	biolink:NamedThing	phloroglucinol O-methyltransferase activity	Catalysis of the reaction: phloroglucinol + S-adenosyl-L-methionine  = H+ + 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-9020		molecular_function											owl:Class	
GO:0047797	biolink:NamedThing	cyclohexanone dehydrogenase activity	Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone.	got7fsn_ti	cyclohexanone:(acceptor) 2-oxidoreductase activity|cyclohexanone:acceptor 2-oxidoreductase activity											KEGG_REACTION:R02234|EC:1.3.99.14|RHEA:21780|MetaCyc:CYCLOHEXANONE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0044551	biolink:NamedThing	envenomation resulting in vasodilation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism.	got7fsn_ti	envenomation resulting in regulation of vasodilation in other organism|envenomation resulting in modulation of vasodilation in other organism						jl	2012-03-29T02:07:45Z						biological_process											owl:Class	
GO:0075521	biolink:NamedThing	microtubule-dependent intracellular transport of viral material towards nucleus	The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.	got7fsn_ti	microtubule-dependent intracellular transport of viral material to nucleus						jl	2011-08-03T02:09:21Z				VZ:983		biological_process											owl:Class	
GO:0019618	biolink:NamedThing	protocatechuate catabolic process, ortho-cleavage	The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate.	got7fsn_ti	protocatechuate degradation, ortho-cleavage|3,4-dihydroxybenzoate catabolic process, ortho-cleavage|protocatechuate catabolic process to beta-ketoadipate|protocatechuate breakdown, ortho-cleavage											MetaCyc:PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY		biological_process											owl:Class	
GO:0019619	biolink:NamedThing	3,4-dihydroxybenzoate catabolic process	The chemical reactions and pathways resulting in the breakdown of  3,4-dihydroxybenzoate.	got7fsn_ti	protocatechuate catabolic process|protocatechuate degradation|protocatechuate breakdown|protocatechuate catabolism													biological_process											owl:Class	
GO:1990910	biolink:NamedThing	response to hypobaric hypoxia	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).	got7fsn_ti							sl	2015-12-07T19:34:14Z						biological_process											owl:Class	
GO:0098737	biolink:NamedThing	protein insertion into plasma membrane	The process that results in the incorporation of a protein into a plasma membrane.  Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.	got7fsn_ti														biological_process											owl:Class	
GO:0051205	biolink:NamedThing	protein insertion into membrane	The process that results in the incorporation of a protein into a biological membrane.  Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.	got7fsn_ti	membrane protein positioning|integral membrane protein positioning|protein-membrane insertion|integral membrane protein localization|membrane protein localization													biological_process											owl:Class	
GO:0047414	biolink:NamedThing	2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity	Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H(2)O + H(+) = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO(2) + NH(4)(+).	got7fsn_ti	compound B hydrolase activity|alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase activity|2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)											RHEA:17677|KEGG_REACTION:R04397|EC:3.5.1.66|Wikipedia:2-(hydroxymethyl)-3-(acetamidomethylene)succinate_amidohydrolase_(deaminating,_decarboxylating)|MetaCyc:3.5.1.66-RXN		molecular_function											owl:Class	
GO:1990911	biolink:NamedThing	response to psychosocial stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism.	got7fsn_ti							sl	2015-12-07T20:38:35Z						biological_process											owl:Class	
GO:0050418	biolink:NamedThing	hydroxylamine reductase activity	Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor.	got7fsn_ti	ammonia:(acceptor) oxidoreductase activity|ammonia:acceptor oxidoreductase activity|hydroxylamine (acceptor) reductase activity											RHEA:22052|EC:1.7.99.1|MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0043819	biolink:NamedThing	precorrin-6A synthase (deacetylating) activity	Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H(+) + precorrin-6X.	got7fsn_ti	S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating)|CobF|precorrin-6X synthase (deacetylating) activity											EC:2.1.1.152|RHEA:18261|MetaCyc:R322-RXN|KEGG_REACTION:R05219		molecular_function											owl:Class	
GO:0018946	biolink:NamedThing	aerobic organosilicon metabolic process	The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen.	got7fsn_ti	aerobic organosilicone metabolism|aerobic organosilicone metabolic process|aerobic organosilicon metabolism											UM-BBD_pathwayID:osi		biological_process											owl:Class	
GO:0018945	biolink:NamedThing	organosilicon metabolic process	The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon.	got7fsn_ti	organosilicone metabolic process|organosilicone metabolism|organosilicon metabolism											UM-BBD_pathwayID:osi		biological_process											owl:Class	
GO:0003940	biolink:NamedThing	L-iduronidase activity	Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.	got7fsn_ti	glycosaminoglycan alpha-L-iduronohydrolase activity|alpha-L-iduronidase activity											Reactome:R-HSA-9036037|MetaCyc:3.2.1.76-RXN|Reactome:R-HSA-2090037|Reactome:R-HSA-1793186|EC:3.2.1.76|Reactome:R-HSA-9036041|Reactome:R-HSA-1678716|Reactome:R-HSA-2206299		molecular_function											owl:Class	
GO:0048339	biolink:NamedThing	paraxial mesoderm development	The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.	got7fsn_ti														biological_process											owl:Class	
GO:0018281	biolink:NamedThing	GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine	The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GSI anchor synthesis via N-seryl-glycosylsphingolipidinositolethanolamine|GSI anchor anabolism via N-seryl-glycosylsphingolipidinositolethanolamine|GSI anchor formation via N-seryl-glycosylsphingolipidinositolethanolamine											RESID:AA0166		biological_process											owl:Class	
GO:0042264	biolink:NamedThing	peptidyl-aspartic acid hydroxylation	The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid.	got7fsn_ti	peptidyl-aspartic acid/asparagine hydroxylation													biological_process											owl:Class	
GO:0007296	biolink:NamedThing	vitellogenesis	The production of yolk. Yolk is a mixture of materials used for embryonic nutrition.	got7fsn_ti	yolk production|yolk formation											Wikipedia:Vitellogenesis		biological_process											owl:Class	
GO:0007028	biolink:NamedThing	cytoplasm organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	got7fsn_ti	cytoplasm organization and biogenesis|cytoplasm organisation													biological_process											owl:Class	
GO:0045267	biolink:NamedThing	proton-transporting ATP synthase, catalytic core	The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.	got7fsn_ti	hydrogen-transporting ATP synthase, catalytic core													cellular_component											owl:Class	
GO:0010212	biolink:NamedThing	response to ionizing radiation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.	got7fsn_ti	response to ionizing radiation stimulus|response to ionising radiation													biological_process											owl:Class	
GO:0007110	biolink:NamedThing	meiosis I cytokinesis	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.	got7fsn_ti	cytokinesis after meiosis I													biological_process											owl:Class	
GO:1900616	biolink:NamedThing	emericellamide A catabolic process	The chemical reactions and pathways resulting in the breakdown of emericellamide A.	got7fsn_ti	emericellamide A degradation|emericellamide A catabolism|emericellamide A breakdown						di	2012-05-15T08:00:19Z						biological_process											owl:Class	
GO:0031005	biolink:NamedThing	filamin binding	Binding to a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.	got7fsn_ti	beta-filamin binding|filamin B binding|filamin-A binding|ABPL binding|filamin C binding|ABP-278/276 binding|filamin-C binding|gamma-filamin binding|filamin-2 binding|filamin-3 binding|alpha-filamin binding|filamin-1 binding|filamin A binding|ABP-280 binding|filamin-B binding										GO:0031007|GO:0031008|GO:0031006			molecular_function											owl:Class	
GO:1990108	biolink:NamedThing	protein linear deubiquitination	A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein.	got7fsn_ti							sp	2013-05-29T05:58:49Z						biological_process											owl:Class	
GO:0099073	biolink:NamedThing	mitochondrion-derived vesicle	A vesicle derived via budding from a mitochondrion.  These vesicles often contain inner membrane and, much more rarely, cristae.	got7fsn_ti	MDV													cellular_component											owl:Class	
GO:0042601	biolink:NamedThing	endospore-forming forespore	Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions.	got7fsn_ti														cellular_component											owl:Class	
GO:0043575	biolink:NamedThing	detection of osmotic stimulus	The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0001631	biolink:NamedThing	cysteinyl leukotriene receptor activity	Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine.	got7fsn_ti	CysLT receptor													molecular_function											owl:Class	
GO:0004974	biolink:NamedThing	leukotriene receptor activity	Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine.	got7fsn_ti														molecular_function											owl:Class	
GO:0008771	biolink:NamedThing	[citrate (pro-3S)-lyase] ligase activity	Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form).	got7fsn_ti	acetate:HS-citrate lyase ligase activity|citrate lyase ligase activity|citrate (pro-3S)-lyase ligase activity|acetate: SH-acyl-carrier-protein enzyme ligase (AMP)|citrate lyase synthetase activity|acetate:citrate-(pro-3S)-lyase(thiol-form) ligase (AMP-forming)											MetaCyc:CITC-RXN|KEGG_REACTION:R04449|RHEA:23788|EC:6.2.1.22		molecular_function											owl:Class	
GO:0033863	biolink:NamedThing	ribose 1,5-bisphosphate phosphokinase activity	Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+).	got7fsn_ti	ATP:ribose-1,5-bisphosphate phosphotransferase activity|ribose 1,5-bisphosphokinase activity|PhnN											KEGG_REACTION:R06836|RHEA:20109|EC:2.7.4.23|MetaCyc:2.7.4.23-RXN		molecular_function											owl:Class	
GO:0051906	biolink:NamedThing	maintenance of pigment granule location	Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere.	got7fsn_ti	maintenance of pigment granule localization													biological_process											owl:Class	
GO:0052230	biolink:NamedThing	modulation of intracellular transport in other organism involved in symbiotic interaction	Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation of intracellular trafficking in other organism|modulation of intracellular transport in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0060670	biolink:NamedThing	branching involved in labyrinthine layer morphogenesis	The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.	got7fsn_ti							dph	2009-06-02T10:40:40Z						biological_process											owl:Class	
GO:0000435	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by galactose	Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.	got7fsn_ti	upregulation of transcription from RNA polymerase II promoter by galactose|stimulation of transcription from RNA polymerase II promoter by galactose|up-regulation of transcription from RNA polymerase II promoter by galactose|up regulation of transcription from RNA polymerase II promoter by galactose|activation of transcription from RNA polymerase II promoter by galactose													biological_process											owl:Class	
GO:0042695	biolink:NamedThing	thelarche	The beginning of development of the breasts in the female.	got7fsn_ti												Wikipedia:Thelarche		biological_process											owl:Class	
GO:0043796	biolink:NamedThing	glyceraldehyde dehydrogenase (NADP) activity	Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+.	got7fsn_ti												EC:1.2.1.89|RHEA:40163		molecular_function											owl:Class	
GO:0034046	biolink:NamedThing	poly(G) binding	Binding to a sequence of guanine residues in an RNA molecule.	got7fsn_ti	poly(rG) binding|poly(G) binding, within an RNA molecule													molecular_function											owl:Class	
GO:0070717	biolink:NamedThing	poly-purine tract binding	Binding to a stretch of purines (adenine or guanine) in an RNA molecule.	got7fsn_ti							mah	2009-06-10T03:32:15Z						molecular_function											owl:Class	
GO:0002292	biolink:NamedThing	T cell differentiation involved in immune response	The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	got7fsn_ti	T cell development involved in immune response|T lymphocyte differentiation during immune response|T-cell differentiation during immune response|T-lymphocyte differentiation during immune response|T cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0036056	biolink:NamedThing	filtration diaphragm	A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.	got7fsn_ti							bf	2011-12-12T04:36:05Z						cellular_component											owl:Class	
GO:0031358	biolink:NamedThing	intrinsic component of chloroplast outer membrane	The component of the chloroplast outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to chloroplast outer membrane													cellular_component											owl:Class	
GO:0031354	biolink:NamedThing	intrinsic component of plastid outer membrane	The component of the plastid outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to plastid outer membrane													cellular_component											owl:Class	
GO:0039626	biolink:NamedThing	viral intermediate capsid	The intermediate layer of a triple concentric icosahedral capsid. Intermediate capsids are part of reoviridae virions.	got7fsn_ti	intermediate capsid						bf	2012-07-18T04:06:25Z						cellular_component											owl:Class	
GO:0047192	biolink:NamedThing	1-alkylglycerophosphocholine O-acetyltransferase activity	Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.	got7fsn_ti	lysopaf:acetyl CoA acetyltransferase activity|blood platelet-activating factor acetyltransferase activity|1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity|platelet-activating factor-synthesizing enzyme activity|lyso-platelet-activating factor:acetyl-CoA acetyltransferase activity|lyso-platelet activating factor:acetyl-CoA acetyltransferase activity|acetyl-CoA:lyso-PAF acetyltransferase activity|acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity|acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity|lysoPAF:acetyl CoA acetyltransferase activity|lyso-GPC:acetyl CoA acetyltransferase activity|acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity|1-alkyl-2-lysolecithin acetyltransferase activity|platelet-activating factor acylhydrolase activity											RHEA:18461|MetaCyc:2.3.1.67-RXN|EC:2.3.1.67		molecular_function											owl:Class	
GO:0021689	biolink:NamedThing	cerebellar molecular layer structural organization	The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	got7fsn_ti	cerebellar molecular layer structural organisation													biological_process											owl:Class	
GO:0070893	biolink:NamedThing	transposon integration	Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome.	got7fsn_ti							mah	2009-09-01T04:08:19Z						biological_process											owl:Class	
GO:0004522	biolink:NamedThing	ribonuclease A activity	Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.	got7fsn_ti	gene S locus-specific glycoproteins|RNase I activity|endoribonuclease I|RNase activity|gene S glycoproteins|SLSG glycoproteins|ceratitis capitata alkaline ribonuclease activity|RNase A activity|pancreatic ribonuclease activity|S-genotype-assocd. glycoproteins|ribonucleate 3'-pyrimidino-oligonucleotidohydrolase activity|ribonucleic phosphatase activity|alkaline ribonuclease activity|pancreatic RNase activity|ribonuclease I activity											EC:4.6.1.18|Wikipedia:Ribonuclease_A|MetaCyc:3.1.27.5-RXN		molecular_function											owl:Class	
GO:0047917	biolink:NamedThing	GDP-glucosidase activity	Catalysis of the reaction: GDP-D-glucose + H(2)O = D-glucose + GDP + H(+).	got7fsn_ti	guanosine diphosphate D-glucose glucohydrolase activity|GDPglucose glucohydrolase activity|guanosine diphosphoglucosidase activity|GDP-glucose glucohydrolase activity|GDPglucosidase activity											RHEA:15049|KEGG_REACTION:R00337|MetaCyc:GDP-GLUCOSIDASE-RXN|EC:3.2.1.42		molecular_function											owl:Class	
GO:0030794	biolink:NamedThing	(S)-coclaurine-N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine.	got7fsn_ti	S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase activity											MetaCyc:2.1.1.140-RXN|EC:2.1.1.140|RHEA:17409		molecular_function											owl:Class	
GO:0110154	biolink:NamedThing	RNA decapping	Cleavage of the 5'-cap of an RNA.	got7fsn_ti							kmv	2019-07-08T17:23:59Z						biological_process											owl:Class	
GO:0060956	biolink:NamedThing	endocardial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.	got7fsn_ti							dph	2009-09-29T03:20:39Z						biological_process											owl:Class	
GO:0052472	biolink:NamedThing	modulation by host of symbiont transcription	Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription.	got7fsn_ti														biological_process											owl:Class	
GO:1901701	biolink:NamedThing	cellular response to oxygen-containing compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.	got7fsn_ti	cellular response to oxygen molecular entity						pr	2012-12-13T15:11:42Z						biological_process											owl:Class	
GO:0060345	biolink:NamedThing	spleen trabecula formation	The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.	got7fsn_ti	spleen trabecula biogenesis|spleen trabeculation													biological_process											owl:Class	
GO:0047957	biolink:NamedThing	4'-methoxyisoflavone 2'-hydroxylase activity	Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O.	got7fsn_ti	isoflavone 2'-monooxygenase activity|formononetin,NADPH:oxygen oxidoreductase (2'-hydroxylating)											RHEA:12388|MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN|EC:1.14.14.89		molecular_function											owl:Class	
GO:0019293	biolink:NamedThing	tyrosine biosynthetic process, by oxidation of phenylalanine	The conversion of phenylalanine to tyrosine.	got7fsn_ti	tyrosine formation, by oxidation of phenylalanine|tyrosine anabolism, by oxidation of phenylalanine|tyrosine synthesis, by oxidation of phenylalanine|L-tyrosine biosynthesis IV	https://github.com/geneontology/go-ontology/issues/20583									GO:0019291	MetaCyc:PWY-6134		biological_process											owl:Class	
GO:0051850	biolink:NamedThing	acquisition of nutrients from symbiont	The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0019289	biolink:NamedThing	rhizobactin 1021 biosynthetic process	The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.	got7fsn_ti	rhizobactin 1021 anabolism|rhizobactin 1021 biosynthesis|rhizobactin 1021 biosynthetic process, peptide modification|rhizobactin 1021 biosynthetic process, peptide formation|rhizobactin 1021 formation|rhizobactin 1021 synthesis										GO:0031194|GO:0031193	MetaCyc:PWY-761		biological_process											owl:Class	
GO:0046494	biolink:NamedThing	rhizobactin 1021 metabolic process	The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.	got7fsn_ti	rhizobactin 1021 metabolism													biological_process											owl:Class	
GO:0030591	biolink:NamedThing	2'-deoxyguanosine DNA ADP-ribosyltransferase activity	Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form.	got7fsn_ti	NAD DNA ADP-ribosyltransferase activity													molecular_function											owl:Class	
GO:0140294	biolink:NamedThing	NAD DNA ADP-ribosyltransferase activity	Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA.	got7fsn_ti							pg	2018-11-22T15:45:35Z						molecular_function											owl:Class	
GO:0039596	biolink:NamedThing	modulation by virus of host protein dephosphorylation	Any viral process that modulates the frequency, rate or extent of dephosphorylation of a host protein.	got7fsn_ti							bf	2012-07-19T11:46:23Z						biological_process											owl:Class	
GO:0021939	biolink:NamedThing	extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation	The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation.	got7fsn_ti	extracellular matrix-granule cell signalling involved in regulation of granule cell precursor proliferation													biological_process											owl:Class	
GO:0035426	biolink:NamedThing	extracellular matrix-cell signaling	Any process that mediates the transfer of information between the extracellular matrix and a cell.	got7fsn_ti	cell-extracellular matrix signalling|extracellular matrix-cell signalling						bf	2010-03-29T02:26:54Z						biological_process											owl:Class	
GO:0030126	biolink:NamedThing	COPI vesicle coat	One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state.	got7fsn_ti	coatomer										GO:0017167			cellular_component											owl:Class	
GO:0019163	biolink:NamedThing	pyridoxamine-phosphate transaminase activity	Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate.	got7fsn_ti	pyridoxamine phosphate aminotransferase activity|pyridoxamine-phosphate aminotransferase activity|pyridoxamine 5'-phosphate transaminase activity|pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase activity|pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming)											RHEA:15877|MetaCyc:PYRDAMPTRANS-RXN|EC:2.6.1.54		molecular_function											owl:Class	
GO:0019146	biolink:NamedThing	arabinose-5-phosphate isomerase activity	Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H(+).	got7fsn_ti	arabinose phosphate isomerase activity|D-arabinose-5-phosphate aldose-ketose-isomerase activity|D-arabinose-5-phosphate ketol-isomerase activity|phosphoarabinoisomerase activity											MetaCyc:DARAB5PISOM-RXN|RHEA:23104|KEGG_REACTION:R01530|EC:5.3.1.13		molecular_function											owl:Class	
GO:0061361	biolink:NamedThing	positive regulation of maintenance of bipolar cell polarity regulating cell shape	Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.	got7fsn_ti							dph	2010-10-13T09:00:59Z						biological_process											owl:Class	
GO:2000247	biolink:NamedThing	positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.	got7fsn_ti							vw	2010-11-11T11:39:34Z						biological_process											owl:Class	
GO:0052576	biolink:NamedThing	carbohydrate storage	The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.	got7fsn_ti								2010-07-23T04:16:56Z						biological_process											owl:Class	
GO:0052575	biolink:NamedThing	carbohydrate localization	Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.	got7fsn_ti	carbohydrate localisation							2010-07-23T04:08:13Z						biological_process											owl:Class	
GO:0102385	biolink:NamedThing	patchoulol synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> seychellene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-13522		molecular_function											owl:Class	
GO:0102474	biolink:NamedThing	eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity	Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+.	got7fsn_ti												MetaCyc:RXN-14080		molecular_function											owl:Class	
GO:0007264	biolink:NamedThing	small GTPase mediated signal transduction	Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.	got7fsn_ti	small GTPase-mediated signal transduction													biological_process											owl:Class	
GO:0010241	biolink:NamedThing	ent-kaurene oxidation to kaurenoic acid	The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase.	got7fsn_ti	ent-kaurene oxidation to kaurenoic acid by ent-kaurene oxidase|ent-kaurene oxidation to ent-kaurenoate|ent-kaurene oxidation to ent-kaur-16-en-19-oate				Note that this term was in molecular function but was moved to biological process as it represents three successive reactions.									biological_process											owl:Class	
GO:0033331	biolink:NamedThing	ent-kaurene metabolic process	The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.	got7fsn_ti	ent-kaurene metabolism													biological_process											owl:Class	
GO:0043743	biolink:NamedThing	LPPG:FO 2-phospho-L-lactate transferase activity	Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP.	got7fsn_ti												EC:2.7.8.28|RHEA:27510		molecular_function											owl:Class	
GO:0070475	biolink:NamedThing	rRNA base methylation	The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0052734	biolink:NamedThing	shikimate 3-dehydrogenase (NAD+) activity	Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.	got7fsn_ti	DHS reductase activity|shikimate:NAD(P)(+) 3-oxidoreductase activity|shikimate oxidoreductase activity|dehydroshikimic reductase activity|shikimate:NAD(P)(+) oxidoreductase activity|3-dehydroshikimic reductase activity|3-dehydroshikimate reductase activity						ai	2011-08-16T04:28:23Z				RHEA:17741|KEGG_REACTION:R06847|EC:1.1.1.282		molecular_function											owl:Class	
GO:0070023	biolink:NamedThing	interleukin-12-interleukin-12 receptor complex	A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer.	got7fsn_ti	IL12-IL12 receptor complex|IL12B-IL12RB1-IL12RB2 complex													cellular_component											owl:Class	
GO:0071764	biolink:NamedThing	nuclear outer membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.	got7fsn_ti	nuclear outer membrane organisation|nuclear outer membrane organization and biogenesis						mah	2010-03-29T04:03:37Z						biological_process											owl:Class	
GO:0018673	biolink:NamedThing	anthraniloyl-CoA monooxygenase activity	Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.	got7fsn_ti	2-aminobenzoyl-CoA monooxygenase/reductase activity|anthraniloyl coenzyme A reductase activity|2-aminobenzoyl-CoA,NAD(P)H:oxygen oxidoreductase (de-aromatizing)											EC:1.14.13.40|MetaCyc:ANTHRANILOYL-COA-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0568		molecular_function											owl:Class	
GO:0030641	biolink:NamedThing	regulation of cellular pH	Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.	got7fsn_ti	cellular hydrogen ion homeostasis|proton homeostasis													biological_process											owl:Class	
GO:1901685	biolink:NamedThing	glutathione derivative metabolic process	The chemical reactions and pathways involving glutathione derivative.	got7fsn_ti	glutathione derivative metabolism						pr	2012-12-05T11:57:11Z						biological_process											owl:Class	
GO:0035963	biolink:NamedThing	cellular response to interleukin-13	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.	got7fsn_ti	cellular response to IL-13						bf	2011-08-01T11:29:42Z						biological_process											owl:Class	
GO:0048029	biolink:NamedThing	monosaccharide binding	Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.	got7fsn_ti														molecular_function											owl:Class	
GO:0061204	biolink:NamedThing	paramyosin filament assembly or disassembly	The formation or disassembly of a filament composed of paramyosin molecules.	got7fsn_ti							dph	2010-07-29T12:26:38Z						biological_process											owl:Class	
GO:0043077	biolink:NamedThing	initiation of acetate catabolic process	The activation of the chemical reactions and pathways resulting in the breakdown of acetate.	got7fsn_ti	initiation of acetate catabolism|initiation of acetate degradation|initiation of acetate breakdown													biological_process											owl:Class	
GO:0045754	biolink:NamedThing	positive regulation of acetate catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.	got7fsn_ti	activation of acetate catabolic process|positive regulation of acetate catabolism|positive regulation of acetate degradation|upregulation of acetate catabolic process|up-regulation of acetate catabolic process|stimulation of acetate catabolic process|up regulation of acetate catabolic process|positive regulation of acetate breakdown													biological_process											owl:Class	
GO:0048541	biolink:NamedThing	Peyer's patch development	The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.	got7fsn_ti	gut-associated lymphoid tissue development|GALT development													biological_process											owl:Class	
GO:0048537	biolink:NamedThing	mucosa-associated lymphoid tissue development	The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes.	got7fsn_ti	NALT development|nasopharyngeal-associated lymphoid tissue development|mucosal-associated lymphoid tissue development|GALT development|BALT development|bronchial-associated lymphoid tissue development|gut-associated lymphoid tissue development	https://github.com/geneontology/go-ontology/issues/19918												biological_process											owl:Class	
GO:0050467	biolink:NamedThing	pentalenene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene.	got7fsn_ti	pentalenene synthetase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming)|2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming)											EC:4.2.3.7|RHEA:18081|MetaCyc:PENTALENENE-SYNTHASE-RXN|KEGG_REACTION:R02305		molecular_function											owl:Class	
GO:0033801	biolink:NamedThing	vitexin 2''-O-rhamnoside 7-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.	got7fsn_ti	S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase activity											EC:2.1.1.153|RHEA:11432|MetaCyc:RXN-4981		molecular_function											owl:Class	
GO:1990749	biolink:NamedThing	polynucleotide adenylyltransferase activator activity	Increases the activity of the enzyme polynucleotide adenylyltransferase.	got7fsn_ti							kmv	2015-05-19T15:02:39Z						molecular_function											owl:Class	
GO:0019736	biolink:NamedThing	peptidyl-sarcosine incorporation	The incorporation of sarcosine (N-methylglycine) into non-coded peptides.	got7fsn_ti												RESID:AA0063		biological_process											owl:Class	
GO:0035130	biolink:NamedThing	post-embryonic pectoral fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0097520	biolink:NamedThing	nucleotide-excision repair, preincision complex	A multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage.	got7fsn_ti	UvrA(2)-UvrB(2) complex|UvrA(2)B(2) complex|UvrB dimer						pr	2013-10-17T14:32:37Z						cellular_component											owl:Class	
GO:0003862	biolink:NamedThing	3-isopropylmalate dehydrogenase activity	Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.	got7fsn_ti	3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity|IMDH activity|IPMDH|beta-IPM dehydrogenase activity|beta-isopropylmalic enzyme|(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity|threo-Ds-3-isopropylmalate dehydrogenase activity|beta-isopropylmalate dehydrogenase activity											RHEA:32271|EC:1.1.1.85|MetaCyc:3-ISOPROPYLMALDEHYDROG-RXN		molecular_function											owl:Class	
GO:0030792	biolink:NamedThing	methylarsonite methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate.	got7fsn_ti					Note that EC:2.1.1.138 was deleted from EC as the reaction is performed by arsenite methyltransferase (EC:2.1.1.137).							EC:2.1.1.-|MetaCyc:2.1.1.138-RXN		molecular_function											owl:Class	
GO:0052623	biolink:NamedThing	ADP dimethylallyltransferase activity	Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate.	got7fsn_ti	dimethylallyl-diphosphate:ADP dimethylallyltransferase activity|ADP isopentenyltransferase activity|2-isopentenyl-diphosphate:ADP delta2-isopentenyltransferase activity|2-isopentenyl-diphosphate:ADP 2-isopentenyltransferase activity						ai	2010-08-26T10:45:44Z				KEGG_REACTION:R08051|MetaCyc:RXN-4305|EC:2.5.1.-		molecular_function											owl:Class	
GO:0098817	biolink:NamedThing	evoked excitatory postsynaptic potential	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse.	got7fsn_ti														biological_process											owl:Class	
GO:0060079	biolink:NamedThing	excitatory postsynaptic potential	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	got7fsn_ti	regulation of excitatory post-synaptic membrane potential|regulation of EPSP													biological_process											owl:Class	
GO:0015846	biolink:NamedThing	polyamine transport	The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0071117	biolink:NamedThing	alpha5-beta1 integrin-fibronectin-NOV complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.	got7fsn_ti	ITGA5-ITGB1-FN-1-NOV complex						mah	2009-11-13T02:19:52Z						cellular_component											owl:Class	
GO:0052381	biolink:NamedThing	tRNA dimethylallyltransferase activity	Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.	got7fsn_ti	tRNA prenyltransferase activity|tRNA isopentenyltransferase activity|dimethylallyl-diphosphate:tRNA dimethylallyltransferase activity				Note that this activity was formerly know in GO and EC as 'tRNA isopentenyltransferase' (EC:2.5.1.8, GO:0004811), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate.			2010-07-23T03:07:33Z			GO:0004811	Reactome:R-HSA-6787567|EC:2.5.1.75|MetaCyc:RXN0-6274|RHEA:26482|Reactome:R-HSA-6784462		molecular_function											owl:Class	
GO:0035298	biolink:NamedThing	regulation of Malpighian tubule size	Ensuring that a Malpighian tubule is the correct length and diameter.	got7fsn_ti														biological_process											owl:Class	
GO:0035150	biolink:NamedThing	regulation of tube size	Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.	got7fsn_ti														biological_process											owl:Class	
GO:0004471	biolink:NamedThing	malate dehydrogenase (decarboxylating) (NAD+) activity	Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+.	got7fsn_ti	NAD-linked malic enzyme|(S)-malate:NAD+ oxidoreductase (decarboxylating)|NAD-malic enzyme activity|(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)|NAD-specific malic enzyme|malate dehydrogenase (decarboxylating) activity|malate dehydrogenase (oxaloacetate-decarboxylating) activity|'malic' enzyme				For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.38), see 'oxaloacetate decarboxylase activity ; GO:0008948'.						GO:0016619|GO:0004472	RHEA:12653|MetaCyc:MALIC-NAD-RXN|EC:1.1.1.39|Reactome:R-HSA-9012268|MetaCyc:1.1.1.39-RXN|KEGG_REACTION:R00214|EC:1.1.1.38		molecular_function											owl:Class	
GO:0043387	biolink:NamedThing	mycotoxin catabolic process	The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus.	got7fsn_ti	mycotoxin catabolism|mycotoxin breakdown|mycotoxin degradation													biological_process											owl:Class	
GO:0009631	biolink:NamedThing	cold acclimation	Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.	got7fsn_ti														biological_process											owl:Class	
GO:0070678	biolink:NamedThing	preprotein binding	Binding to a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.	got7fsn_ti	unprocessed protein binding						mah	2009-05-29T03:41:54Z						molecular_function											owl:Class	
GO:0071480	biolink:NamedThing	cellular response to gamma radiation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.	got7fsn_ti	cellular response to gamma ray|cellular response to gamma-ray photon						mah	2009-12-18T02:00:50Z						biological_process											owl:Class	
GO:0010332	biolink:NamedThing	response to gamma radiation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.	got7fsn_ti	response to gamma ray|response to gamma-ray photon													biological_process											owl:Class	
GO:0008057	biolink:NamedThing	eye pigment granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye.	got7fsn_ti	eye pigment granule organization and biogenesis|eye pigment granule organisation										GO:0008059|GO:0045318|GO:0048751			biological_process											owl:Class	
GO:0102118	biolink:NamedThing	gibberellin A4 carboxyl methyltransferase activity	Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine  <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:36107|EC:2.1.1.276|MetaCyc:RXN-11359		molecular_function											owl:Class	
GO:0030281	biolink:NamedThing	structural constituent of cutaneous appendage	The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers.	got7fsn_ti														molecular_function											owl:Class	
GO:0061498	biolink:NamedThing	intermediate layer of mitotic spindle pole body	Structure between the central and outer plaques of the mitotic spindle pole body.	got7fsn_ti							dph	2012-12-11T09:17:14Z						cellular_component											owl:Class	
GO:0102267	biolink:NamedThing	tRNA-dihydrouridine20b synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) <=> H+ + a uracil20b in tRNA + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-12476		molecular_function											owl:Class	
GO:0090116	biolink:NamedThing	C-5 methylation of cytosine	The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule.	got7fsn_ti							tb	2009-12-07T11:58:47Z						biological_process											owl:Class	
GO:0021862	biolink:NamedThing	early neuron differentiation in forebrain	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0051777	biolink:NamedThing	ent-kaurenoate oxidase activity	Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).	got7fsn_ti	ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating) activity|ent-kaurenoic acid oxidase activity				Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-7-alpha-hydroxykaurenoate oxidase activity ; GO:0051778' and 'gibberellin 12-aldehyde oxidase activity ; GO:0051779'.							RHEA:19241|MetaCyc:1.14.13.79-RXN		molecular_function											owl:Class	
GO:0060095	biolink:NamedThing	zinc potentiation of synaptic transmission, glycinergic	Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.	got7fsn_ti	zinc potentiation of glycinergic synaptic transmission													biological_process											owl:Class	
GO:0060094	biolink:NamedThing	positive regulation of synaptic transmission, glycinergic	Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.	got7fsn_ti	positive regulation of glycinergic synaptic transmission													biological_process											owl:Class	
GO:0034550	biolink:NamedThing	dimethylarsinate reductase activity	Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O.	got7fsn_ti												UM-BBD_reactionID:r0838|EC:1.97.1.-		molecular_function											owl:Class	
GO:0032218	biolink:NamedThing	riboflavin transport	The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.	got7fsn_ti														biological_process											owl:Class	
GO:0004855	biolink:NamedThing	xanthine oxidase activity	Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide.	got7fsn_ti	xanthine:xanthine oxidase activity|schardinger enzyme|hypoxanthine-xanthine oxidase activity|Schardinger enzyme activity|xanthine:O(2) oxidoreductase activity|xanthine:oxygen oxidoreductase activity|xanthine oxidoreductase activity|xanthine:O2 oxidoreductase activity											MetaCyc:XANTHINE-OXIDASE-RXN|Reactome:R-HSA-74247|EC:1.17.3.2|Reactome:R-HSA-74258|UM-BBD_enzymeID:e0781|RHEA:21132		molecular_function											owl:Class	
GO:0044184	biolink:NamedThing	host cell late endosome	A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.	got7fsn_ti							jl	2009-10-15T02:58:34Z						cellular_component											owl:Class	
GO:0044879	biolink:NamedThing	mitotic morphogenesis checkpoint signaling	A signaling process that contributes to a mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth.	got7fsn_ti	signal transduction involved in septin checkpoint|signalling pathway involved in morphogenesis checkpoint|signaling pathway involved in morphogenesis checkpoint|signalling cascade involved in septin checkpoint|septin checkpoint|signaling cascade involved in morphogenesis checkpoint|morphogenesis checkpoint|signalling cascade involved in morphogenesis checkpoint|signalling pathway involved in septin checkpoint|signaling pathway involved in septin checkpoint|signaling cascade involved in septin checkpoint|signal transduction involved in morphogenesis checkpoint	https://github.com/geneontology/go-ontology/issues/20935					jl	2015-01-13T16:03:07Z			GO:1903822			biological_process											owl:Class	
GO:0019954	biolink:NamedThing	asexual reproduction	The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.	got7fsn_ti	parthenogenesis											Wikipedia:Asexual_reproduction		biological_process											owl:Class	
GO:0004336	biolink:NamedThing	galactosylceramidase activity	Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.	got7fsn_ti	galactosylceramide beta-galactosidase activity|galactosylcerebrosidase activity|galactocerebroside-beta-D-galactosidase activity|galactocerebroside beta-galactosidase activity|galactosylceramidase I|galactocerebrosidase activity|beta-galactocerebrosidase activity|lactosylceramidase I|D-galactosyl-N-acylsphingosine galactohydrolase activity|ceramide galactosidase activity|beta-galactosylceramidase activity|lactosylceramidase activity|cerebroside beta-galactosidase activity|galactocerebroside galactosidase activity|galcerase activity|cerebroside galactosidase activity											EC:3.2.1.46|MetaCyc:GALACTOSYLCERAMIDASE-RXN|RHEA:14297|Reactome:R-HSA-1606564		molecular_function											owl:Class	
GO:0030843	biolink:NamedThing	negative regulation of intermediate filament depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization.	got7fsn_ti	inhibition of intermediate filament depolymerization|down regulation of intermediate filament depolymerization|down-regulation of intermediate filament depolymerization|negative regulation of intermediate filament polymerization and/or depolymerization|downregulation of intermediate filament depolymerization				Note that this term was split from 'negative regulation of intermediate filament polymerization and/or depolymerization ; GO:0045825' (sibling term 'negative regulation of intermediate filament polymerization ; GO:0030840').									biological_process											owl:Class	
GO:0070312	biolink:NamedThing	RAD52-ERCC4-ERCC1 complex	A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.	got7fsn_ti					Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.									cellular_component											owl:Class	
GO:0032129	biolink:NamedThing	histone deacetylase activity (H3-K9 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0030835	biolink:NamedThing	negative regulation of actin filament depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization.	got7fsn_ti	actin filament stabilization|downregulation of actin filament depolymerization|inhibition of actin filament depolymerization|negative regulation of actin depolymerization|negative regulation of actin polymerization and/or depolymerization|down-regulation of actin filament depolymerization|down regulation of actin filament depolymerization				Note that this term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin polymerization ; GO:0030837').						GO:0030044			biological_process											owl:Class	
GO:0102899	biolink:NamedThing	dehydroabietadienol hydroxylase activity	Catalysis of the reaction: H+ + dehydroabietadienol + NADPH + O2 <=> dehydroabietadiene-diol + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-8532		molecular_function											owl:Class	
GO:1900607	biolink:NamedThing	tensidol B catabolic process	The chemical reactions and pathways resulting in the breakdown of tensidol B.	got7fsn_ti	tensidol B degradation|tensidol B catabolism|tensidol B breakdown						di	2012-05-15T06:58:43Z						biological_process											owl:Class	
GO:0106319	biolink:NamedThing	(R)-limonene 1,2-monooxygenase NADH activity	Catalysis of the reaction: (4R)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4R)-limonene-1,2-epoxide.	got7fsn_ti							hjd	2020-09-23T15:20:27Z				RHEA:26093|EC:1.14.13.107		molecular_function											owl:Class	
GO:0072029	biolink:NamedThing	long nephron development	The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla.	got7fsn_ti	juxtamedullary nephron development						mah	2010-01-25T02:49:08Z						biological_process											owl:Class	
GO:0035724	biolink:NamedThing	CD24 biosynthetic process	The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation.	got7fsn_ti	CD24 anabolism|CD24 synthesis|CD24 biosynthesis|CD24 formation						bf	2011-03-07T11:32:54Z						biological_process											owl:Class	
GO:0052155	biolink:NamedThing	modulation by symbiont of host cell-mediated immune response	Any process in which an organism modulates the frequency, rate or extent of any form of cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction|modulation by organism of host cell-based immune response										GO:0052294			biological_process											owl:Class	
GO:0060521	biolink:NamedThing	mesenchymal-epithelial cell signaling involved in prostate induction	Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate.	got7fsn_ti	mesenchymal-epithelial cell signalling involved in prostate induction													biological_process											owl:Class	
GO:0060739	biolink:NamedThing	mesenchymal-epithelial cell signaling involved in prostate gland development	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.	got7fsn_ti	mesenchymal-epithelial cell signalling involved in prostate gland development						dph	2009-06-15T09:35:08Z						biological_process											owl:Class	
GO:0051275	biolink:NamedThing	beta-glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-glucans.	got7fsn_ti	beta-glucan catabolism|beta-glucan degradation|beta-glucan breakdown													biological_process											owl:Class	
GO:0031072	biolink:NamedThing	heat shock protein binding	Binding to a heat shock protein, a protein synthesized or activated in response to heat shock.	got7fsn_ti														molecular_function											owl:Class	
GO:0035513	biolink:NamedThing	oxidative RNA demethylation	The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms.	got7fsn_ti							bf	2010-04-30T02:25:35Z						biological_process											owl:Class	
GO:0033813	biolink:NamedThing	deacetylcephalosporin-C acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA.	got7fsn_ti	CPC acetylhydrolase activity|acetyl-CoA:DAC O-acetyltransferase activity|cefG|acetyl-CoA:deacetylcephalosporin-C acetyltransferase activity|acetyl coenzyme A:DAC acetyltransferase activity|acetyl-CoA:deacetylcephalosporin-C O-acetyltransferase activity|acetyl-CoA:DAC acetyltransferase activity|DAC-AT|deacetylcephalosporin C acetyltransferase activity|DAC acetyltransferase activity											KEGG_REACTION:R03064|RHEA:23860|EC:2.3.1.175|MetaCyc:2.3.1.175-RXN		molecular_function											owl:Class	
GO:0030987	biolink:NamedThing	high molecular weight kininogen receptor binding	Binding to a high molecular weight kininogen receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0002345	biolink:NamedThing	peripheral B cell receptor editing	The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation.	got7fsn_ti	peripheral B lymphocyte receptor editing|peripheral B-lymphocyte receptor editing|peripheral B-cell receptor editing													biological_process											owl:Class	
GO:0043101	biolink:NamedThing	purine-containing compound salvage	Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.	got7fsn_ti	purine salvage													biological_process											owl:Class	
GO:0044015	biolink:NamedThing	histone acetyltransferase activity (H2B-K12 specific)	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12).	got7fsn_ti	histone lysine N-acetyltransferase activity (H2B-K12 specific)													molecular_function											owl:Class	
GO:0015630	biolink:NamedThing	microtubule cytoskeleton	The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:1900594	biolink:NamedThing	(+)-kotanin metabolic process	The chemical reactions and pathways involving (+)-kotanin.	got7fsn_ti	(+)-kotanin metabolism						di	2012-05-15T06:54:19Z						biological_process											owl:Class	
GO:0045003	biolink:NamedThing	double-strand break repair via synthesis-dependent strand annealing	SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break.	got7fsn_ti	mitotic gene conversion|SDSA													biological_process											owl:Class	
GO:0003756	biolink:NamedThing	protein disulfide isomerase activity	Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.	got7fsn_ti	protein disulfide-isomerase reaction|protein disulfide-isomerase|protein cysteine-thiol oxidation|disulphide bond formation|protein thiol-disulfide exchange|S-S rearrangase activity|protein thiol-disulphide exchange|disulphide bond biosynthesis|protein disulphide isomerase activity										GO:0006467	MetaCyc:5.3.4.1-RXN|EC:5.3.4.1|Reactome:R-HSA-8950183|Reactome:R-HSA-8950456|Reactome:R-HSA-8950113		molecular_function											owl:Class	
GO:0045144	biolink:NamedThing	meiotic sister chromatid segregation	The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.	got7fsn_ti	meiosis II, chromosome segregation													biological_process											owl:Class	
GO:0102038	biolink:NamedThing	4-nitrobenzyl alcohol oxidase activity	Catalysis of the reaction: 4-nitrobenzyl alcohol + O2 <=> 4-nitrobenzaldehyde + hydrogen peroxide.	got7fsn_ti												MetaCyc:R362-RXN		molecular_function											owl:Class	
GO:0016611	biolink:NamedThing	iron-iron nitrogenase complex	An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.	got7fsn_ti					Note that it is not established whether the nitrogenase exists in vivo in a specific particle or whether the nitrogenase proteins are bound nonspecifically to the membranes of some cells.									cellular_component											owl:Class	
GO:0016610	biolink:NamedThing	nitrogenase complex	An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.	got7fsn_ti														cellular_component											owl:Class	
GO:0046218	biolink:NamedThing	indolalkylamine catabolic process	The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.	got7fsn_ti	indolalkylamine breakdown|indolalkylamine degradation|indolalkylamine catabolism													biological_process											owl:Class	
GO:0047048	biolink:NamedThing	3-hydroxybenzyl-alcohol dehydrogenase activity	Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + H(+) + NADPH.	got7fsn_ti	3-hydroxybenzyl-alcohol:NADP+ oxidoreductase activity|m-hydroxybenzylalcohol dehydrogenase activity|m-hydroxybenzyl alcohol (NADP) dehydrogenase activity|m-hydroxybenzyl alcohol dehydrogenase activity											RHEA:22340|MetaCyc:1.1.1.97-RXN|KEGG_REACTION:R04136|EC:1.1.1.97		molecular_function											owl:Class	
GO:0036323	biolink:NamedThing	vascular endothelial growth factor receptor-1 signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-1 (VEGFR-1) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	VEGFR1 signaling pathway|VEGFR-1 signaling pathway|FLT1 signaling pathway						bf	2012-09-04T15:11:21Z						biological_process											owl:Class	
GO:0006531	biolink:NamedThing	aspartate metabolic process	The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.	got7fsn_ti	aspartate metabolism													biological_process											owl:Class	
GO:0010202	biolink:NamedThing	response to low fluence red light stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec.	got7fsn_ti														biological_process											owl:Class	
GO:0009645	biolink:NamedThing	response to low light intensity stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.	got7fsn_ti														biological_process											owl:Class	
GO:0045577	biolink:NamedThing	regulation of B cell differentiation	Any process that modulates the frequency, rate or extent of B cell differentiation.	got7fsn_ti	regulation of B lymphocyte differentiation|regulation of B-cell differentiation|regulation of B cell development|regulation of B-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0005007	biolink:NamedThing	fibroblast growth factor-activated receptor activity	Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	fibroblast growth factor receptor activity|FGF receptor activity|FGF-activated receptor activity|FGFR				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand FGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.									molecular_function											owl:Class	
GO:0019344	biolink:NamedThing	cysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.	got7fsn_ti	cysteine anabolism|cysteine formation|cysteine synthesis|cysteine biosynthesis													biological_process											owl:Class	
GO:0043034	biolink:NamedThing	costamere	Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix.	got7fsn_ti												Wikipedia:Costamere		cellular_component											owl:Class	
GO:0036259	biolink:NamedThing	aerobic raffinose catabolic process	The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen.	got7fsn_ti	aerobic raffinose catabolism|aerobic raffinose degradation|aerobic raffinose breakdown						bf	2012-06-15T01:14:51Z						biological_process											owl:Class	
GO:0034484	biolink:NamedThing	raffinose catabolic process	The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	raffinose degradation|raffinose breakdown|raffinose catabolism													biological_process											owl:Class	
GO:0099099	biolink:NamedThing	G-protein gated ion channel activity	An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.	got7fsn_ti														molecular_function											owl:Class	
GO:0050912	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of taste	The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.	got7fsn_ti	sensory detection of chemical stimulus during perception of taste|perception of taste, sensory detection of chemical stimulus|perception of taste, sensory transduction of chemical stimulus|sensory transduction of taste|sensory transduction of chemical stimulus during perception of taste|sensory detection of taste|perception of taste, detection of chemical stimulus|taste perception													biological_process											owl:Class	
GO:0050239	biolink:NamedThing	pyrithiamine deaminase activity	Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3.	got7fsn_ti	1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase activity											MetaCyc:PYRITHIAMIN-DEAMINASE-RXN|EC:3.5.4.20|RHEA:14537		molecular_function											owl:Class	
GO:0017119	biolink:NamedThing	Golgi transport complex	A  multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. Composed of 8 subunits COG1-8.	got7fsn_ti	COG complex|conserved oligomeric Golgi complex|Sec34/35 complex													cellular_component											owl:Class	
GO:0042657	biolink:NamedThing	MHC class II protein binding, via lateral surface	Binding to the lateral surface of major histocompatibility complex class II molecules.	got7fsn_ti	major histocompatibility complex class II protein binding, via lateral surface													molecular_function											owl:Class	
GO:0042289	biolink:NamedThing	MHC class II protein binding	Binding to a major histocompatibility complex class II molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.	got7fsn_ti	major histocompatibility complex class II binding|major histocompatibility complex class II ligand				Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children.									molecular_function											owl:Class	
GO:0008139	biolink:NamedThing	nuclear localization sequence binding	Binding to a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus.	got7fsn_ti	NLS binding|nuclear localization signal binding|nuclear localisation sequence binding													molecular_function											owl:Class	
GO:0060374	biolink:NamedThing	mast cell differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	got7fsn_ti														biological_process											owl:Class	
GO:0016308	biolink:NamedThing	1-phosphatidylinositol-4-phosphate 5-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+).	got7fsn_ti	PIP5K|ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity|diphosphoinositide kinase activity|PIP kinase activity|phosphatidylinositol-4-phosphate 5-kinase activity|type I PIP kinase activity|1-phosphatidylinositol-4-phosphate kinase, class IA|1-phosphatidylinositol-4-phosphate kinase activity|1-phosphatidylinositol-4-phosphate kinase, class IB|phosphatidylinositol 4-phosphate kinase activity|PtdIns(4)P-5-kinase activity										GO:0045215|GO:0004431	EC:2.7.1.68|KEGG_REACTION:R03469|Reactome:R-HSA-1676082|Reactome:R-HSA-3772436|MetaCyc:2.7.1.68-RXN|RHEA:14425|Reactome:R-HSA-8868066		molecular_function											owl:Class	
GO:0018445	biolink:NamedThing	prothoracicotrophic hormone activity	The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects.	got7fsn_ti														molecular_function											owl:Class	
GO:0008865	biolink:NamedThing	fructokinase activity	Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.	got7fsn_ti	ATP:D-fructose 6-phosphotransferase activity|D-fructokinase activity|D-fructose(D-mannose)kinase activity|fructokinase (phosphorylating)											MetaCyc:FRUCTOKINASE-RXN|RHEA:16125|EC:2.7.1.4		molecular_function											owl:Class	
GO:0004396	biolink:NamedThing	hexokinase activity	Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate.	got7fsn_ti	hexokinase D|hexokinase type III activity|glucose ATP phosphotransferase activity|ATP-dependent hexokinase activity|hexokinase type I activity|hexokinase type IV|hexokinase (phosphorylating)|hexokinase type IV glucokinase activity|ATP:D-hexose 6-phosphotransferase activity|hexokinase type II activity|hexokinase type IV (glucokinase) activity											RHEA:22740|MetaCyc:HEXOKINASE-RXN|EC:2.7.1.1		molecular_function											owl:Class	
GO:0010788	biolink:NamedThing	COPI coating of Golgi vesicle, cis-Golgi to rough ER	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat.	got7fsn_ti														biological_process											owl:Class	
GO:0048205	biolink:NamedThing	COPI coating of Golgi vesicle	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.	got7fsn_ti	COPI coating of Golgi-derived vesicle|COPI vesicle coating													biological_process											owl:Class	
GO:0018686	biolink:NamedThing	6-hydroxy pseudo-oxynicotine monooxygenase activity	Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine.	got7fsn_ti												UM-BBD_reactionID:r0480|EC:1.14.18.-		molecular_function											owl:Class	
GO:0060891	biolink:NamedThing	limb granular cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.	got7fsn_ti							dph	2009-08-13T01:33:14Z						biological_process											owl:Class	
GO:0072761	biolink:NamedThing	cellular response to capsazepine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.	got7fsn_ti							mah	2012-11-09T11:47:53Z						biological_process											owl:Class	
GO:1901594	biolink:NamedThing	response to capsazepine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.	got7fsn_ti							mah	2012-11-07T17:16:53Z						biological_process											owl:Class	
GO:0009117	biolink:NamedThing	nucleotide metabolic process	The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).	got7fsn_ti	nucleotide metabolism													biological_process											owl:Class	
GO:0001935	biolink:NamedThing	endothelial cell proliferation	The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.	got7fsn_ti														biological_process											owl:Class	
GO:0033056	biolink:NamedThing	D-ornithine metabolic process	The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid.	got7fsn_ti	D-ornithine metabolism													biological_process											owl:Class	
GO:0021998	biolink:NamedThing	neural plate mediolateral regionalization	The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate.	got7fsn_ti	neural plate mediolateral pattern formation													biological_process											owl:Class	
GO:0097125	biolink:NamedThing	cyclin B1-CDK1 complex	A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:45:15Z						cellular_component											owl:Class	
GO:0106236	biolink:NamedThing	rhamnolipid biosynthesis	The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal.	got7fsn_ti	rhamnolipid production						hjd	2019-12-09T18:37:49Z						biological_process											owl:Class	
GO:0009247	biolink:NamedThing	glycolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).	got7fsn_ti	glycolipid anabolism|glycolipid formation|glycolipid biosynthesis|glycolipid synthesis											MetaCyc:PWY-401		biological_process											owl:Class	
GO:0010134	biolink:NamedThing	sulfate assimilation via adenylyl sulfate reduction	The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase.	got7fsn_ti	sulphate assimilation via adenylyl sulphate reduction											MetaCyc:SULFMETII-PWY		biological_process											owl:Class	
GO:0016750	biolink:NamedThing	O-succinyltransferase activity	Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0097325	biolink:NamedThing	melanocyte proliferation	The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.	got7fsn_ti							pr	2012-06-08T10:10:12Z						biological_process											owl:Class	
GO:0052661	biolink:NamedThing	S-lactaldehyde reductase activity	Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+.	got7fsn_ti	L-lactaldehyde:propanediol oxidoreductase activity|(S)-propane-1,2-diol:NAD+ oxidoreductase activity											KEGG_REACTION:R02258|MetaCyc:LACTALDREDUCT-RXN|RHEA:15933		molecular_function											owl:Class	
GO:0080097	biolink:NamedThing	L-tryptophan:pyruvate aminotransferase activity	Catalysis of the reaction: L-tryptophan + pyruvate = 3-(indol-3-yl)pyruvate + L-alanine.	got7fsn_ti					This reaction falls within the larger set of reactions associated with EC:2.6.1.28 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.28; note: 3-indole-2-oxopropanoate = indolepyruvate = 3-(indol-3-yl)pyruvate).		dhl	2009-04-23T03:45:23Z				MetaCyc:RXN-10139|EC:2.6.1.99|RHEA:27586		molecular_function											owl:Class	
GO:0009625	biolink:NamedThing	response to insect	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.	got7fsn_ti	response to insects										GO:0043019			biological_process											owl:Class	
GO:0043078	biolink:NamedThing	polar nucleus	Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus.	got7fsn_ti														cellular_component											owl:Class	
GO:0035756	biolink:NamedThing	transepithelial migration of symbiont in host	The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	migration of symbiont within host by transepithelial trafficking|migration in host through an epithelial cell layer|transmigration of symbiont in host						bf	2011-03-24T10:20:03Z						biological_process											owl:Class	
GO:1900769	biolink:NamedThing	fonsecin biosynthetic process	The chemical reactions and pathways resulting in the formation of fonsecin.	got7fsn_ti	fonsecin biosynthesis|fonsecin synthesis|fonsecin anabolism|fonsecin formation						di	2012-06-04T09:21:49Z						biological_process											owl:Class	
GO:0043659	biolink:NamedThing	symbiosome	A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane).	got7fsn_ti														cellular_component											owl:Class	
GO:0102592	biolink:NamedThing	delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity	Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> violdelphin + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-15354		molecular_function											owl:Class	
GO:0070391	biolink:NamedThing	response to lipoteichoic acid	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	got7fsn_ti	response to LTA													biological_process											owl:Class	
GO:0047375	biolink:NamedThing	N-acetylgalactosaminoglycan deacetylase activity	Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan.	got7fsn_ti	Vi-polysaccharide deacetylase activity|N-acetyl-D-galactosaminoglycan acetylhydrolase activity|polysaccharide deacetylase activity|N-acetyl galactosaminoglycan deacetylase activity											MetaCyc:3.1.1.58-RXN|EC:3.1.1.58		molecular_function											owl:Class	
GO:0060025	biolink:NamedThing	regulation of synaptic activity	Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.	got7fsn_ti														biological_process											owl:Class	
GO:0018630	biolink:NamedThing	3,5-xylenol methylhydroxylase activity	Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol.	got7fsn_ti												MetaCyc:3-5-XYLENOL-METHYLHYDROXYLASE-RXN|EC:1.14.13.-|UM-BBD_reactionID:r0081		molecular_function											owl:Class	
GO:0001539	biolink:NamedThing	cilium or flagellum-dependent cell motility	Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.	got7fsn_ti	ciliary/flagellar motility|ciliary or bacterial-type flagellar motility				Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC.									biological_process											owl:Class	
GO:0004822	biolink:NamedThing	isoleucine-tRNA ligase activity	Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+).	got7fsn_ti	isoleucine-tRNA synthetase activity|isoleucine translase activity|isoleucine-transfer RNA ligase activity|L-isoleucine:tRNAIle ligase (AMP-forming)|isoleucyl-transfer ribonucleate synthetase activity|isoleucyl-transfer RNA synthetase activity|isoleucyl-tRNA synthetase activity											KEGG_REACTION:R03656|Reactome:R-HSA-380176|Reactome:R-HSA-379893|EC:6.1.1.5|MetaCyc:ISOLEUCINE--TRNA-LIGASE-RXN|RHEA:11060		molecular_function											owl:Class	
GO:0099619	biolink:NamedThing	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.	got7fsn_ti	10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity|UDP-L-Ara4N formyltransferase activity|ArnAFT activity											EC:2.1.2.13|RHEA:24706		molecular_function											owl:Class	
GO:0005008	biolink:NamedThing	hepatocyte growth factor-activated receptor activity	Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	hepatocyte growth factor receptor activity|HGF-activated receptor activity|HGF receptor activity				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand HGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.									molecular_function											owl:Class	
GO:0051686	biolink:NamedThing	establishment of ER localization	The directed movement of the endoplasmic reticulum to a specific location.	got7fsn_ti	establishment of ER localisation|establishment of endoplasmic reticulum localization													biological_process											owl:Class	
GO:0006700	biolink:NamedThing	C21-steroid hormone biosynthetic process	The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.	got7fsn_ti	C21-steroid hormone synthesis|C21-steroid hormone formation|C21-steroid hormone biosynthesis|C21-steroid hormone anabolism													biological_process											owl:Class	
GO:0102734	biolink:NamedThing	brassinolide synthase activity	Catalysis of the reaction: H+ + castasterone + NADPH + O2 <=> brassinolide + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-720		molecular_function											owl:Class	
GO:0036497	biolink:NamedThing	eIF2alpha dephosphorylation in response to endoplasmic reticulum stress	The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.	got7fsn_ti	eIF2alpha dephosphorylation in response to ER stress|regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress						bf	2015-02-05T10:24:18Z						biological_process											owl:Class	
GO:0071772	biolink:NamedThing	response to BMP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.	got7fsn_ti	response to bone morphogenetic protein stimulus|response to BMP stimulus						mah	2010-08-31T11:02:11Z						biological_process											owl:Class	
GO:0018185	biolink:NamedThing	poly-N-methyl-propylamination	The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin.	got7fsn_ti												RESID:AA0278		biological_process											owl:Class	
GO:0018184	biolink:NamedThing	protein polyamination	The modification of a protein amino acid by polyamination.	got7fsn_ti	protein amino acid polyamination													biological_process											owl:Class	
GO:0005484	biolink:NamedThing	SNAP receptor activity	Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.	got7fsn_ti	SNAP-25|R-SNARE activity|SNARE|Q-SNARE activity|v-SNARE activity|t-SNARE activity										GO:0005486|GO:0005485			molecular_function											owl:Class	
GO:0018978	biolink:NamedThing	anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process	The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.	got7fsn_ti	anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism|anaerobic DDT metabolism|anaerobic DDT metabolic process											UM-BBD_pathwayID:ddt2		biological_process											owl:Class	
GO:0018977	biolink:NamedThing	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process	The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.	got7fsn_ti	DDT metabolic process|DDT metabolism|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism											UM-BBD_pathwayID:ddt		biological_process											owl:Class	
GO:0018638	biolink:NamedThing	toluene 4-monooxygenase activity	Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene.	got7fsn_ti												UM-BBD_enzymeID:e0225|EC:1.14.13.-		molecular_function											owl:Class	
GO:0050300	biolink:NamedThing	aminoglycoside 6-kinase activity	Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 6-phosphate.	got7fsn_ti	streptidine kinase (phosphorylating)|streptidine kinase activity|streptomycin 6-phosphotransferase activity|streptomycin 6-O-phosphotransferase activity|SM 6-kinase activity|ATP:streptomycin 6-phosphotransferase activity|APH(6) activity|streptomycin 6-kinase activity|streptomycin 6-kinase (phosphorylating)											MetaCyc:STREPTOMYCIN-6-KINASE-RXN|KEGG_REACTION:R02225|EC:2.7.1.72|RHEA:22268		molecular_function											owl:Class	
GO:0032303	biolink:NamedThing	regulation of icosanoid secretion	Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.	got7fsn_ti	regulation of eicosanoid secretion													biological_process											owl:Class	
GO:2000191	biolink:NamedThing	regulation of fatty acid transport	Any process that modulates the frequency, rate or extent of fatty acid transport.	got7fsn_ti							rl	2010-10-18T10:37:13Z						biological_process											owl:Class	
GO:0061390	biolink:NamedThing	positive regulation of direction of cell growth	Any process that increases the direction of cell growth.	got7fsn_ti							dph	2011-07-14T10:22:55Z						biological_process											owl:Class	
GO:0030307	biolink:NamedThing	positive regulation of cell growth	Any process that activates or increases the frequency, rate, extent or direction of cell growth.	got7fsn_ti	up regulation of cell growth|stimulation of cell growth|activation of cell growth|upregulation of cell growth|up-regulation of cell growth													biological_process											owl:Class	
GO:0035482	biolink:NamedThing	gastric motility	The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum.	got7fsn_ti							bf	2010-04-23T10:44:59Z						biological_process											owl:Class	
GO:0070476	biolink:NamedThing	rRNA (guanine-N7)-methylation	The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0019137	biolink:NamedThing	thioglucosidase activity	Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar.	got7fsn_ti	sinigrinase activity|thioglucoside glucohydrolase activity|sinigrase activity|myrosinase activity											MetaCyc:RXN-9946|EC:3.2.1.147		molecular_function											owl:Class	
GO:0018775	biolink:NamedThing	2-hydroxymuconate-semialdehyde hydrolase activity	Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate.	got7fsn_ti	2-hydroxymuconate-semialdehyde formylhydrolase activity|2-hydroxymuconic semialdehyde hydrolase activity|HMSH|HOD hydrolase activity											MetaCyc:3.7.1.9-RXN|RHEA:14549|EC:3.7.1.9|UM-BBD_enzymeID:e0139		molecular_function											owl:Class	
GO:0010054	biolink:NamedThing	trichoblast differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair.	got7fsn_ti	trichoblast cell differentiation													biological_process											owl:Class	
GO:0010053	biolink:NamedThing	root epidermal cell differentiation	The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.	got7fsn_ti														biological_process											owl:Class	
GO:0047286	biolink:NamedThing	NAD+-diphthamide ADP-ribosyltransferase activity	Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide.	got7fsn_ti	ADP-ribosyltransferase activity|NAD-diphthamide ADP-ribosyltransferase activity|NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase activity|mono(ADP-ribosyl)transferase activity											RHEA:11820|MetaCyc:RXN-11372|EC:2.4.2.36|Reactome:R-HSA-5336421		molecular_function											owl:Class	
GO:0008545	biolink:NamedThing	JUN kinase kinase activity	Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.	got7fsn_ti	JNKK											Reactome:R-HSA-168162		molecular_function											owl:Class	
GO:0004708	biolink:NamedThing	MAP kinase kinase activity	Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.	got7fsn_ti	MKK2|MEK2|MAPKK1|MAP kinase kinase 7 activity|MKK7|MKK4|MKK|MAP2K|MAPKK activity|MAPKK|MAP kinase or ERK kinase activity|ERK activator kinase activity|STK27|MKK6|MEK1|MEK activity|MAPK activator activity|mitogen-activated protein kinase kinase activity|MAP kinase kinase 4 activity|ATP:protein phosphotransferase (MAPKKK-activated) activity											MetaCyc:2.7.12.2-RXN|Reactome:R-HSA-450333|EC:2.7.12.2|Reactome:R-HSA-3238999|Reactome:R-HSA-448951|Reactome:R-HSA-1247960|Reactome:R-HSA-5218804		molecular_function											owl:Class	
GO:0051729	biolink:NamedThing	germline cell cycle switching, mitotic to meiotic cell cycle	The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.	got7fsn_ti	germline conversion to meiosis|germline initiation of meiosis|germline entry into meiosis|germline cell cycle switching, mitosis to meiosis|germline initiation of meiotic cell cycle|germline entry into meiotic cell cycle|germline conversion to meiotic cell cycle|germline meiotic entry													biological_process											owl:Class	
GO:0052752	biolink:NamedThing	reduced coenzyme F420:heterodisulfide oxidoreductase activity	Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH.	got7fsn_ti	F420-dependent heterodisulfide oxidoreductase activity|coenzyme F420-dependent heterodisulfide oxidoreductase activity|F420H2:heterodisulfide oxidoreductase activity						ai	2011-09-21T04:21:16Z						molecular_function											owl:Class	
GO:0102932	biolink:NamedThing	pterocarpan reductase activity	Catalysis of the reaction: H+ + (-)-medicarpin + NADPH = (+)-vestitol + NADP.	got7fsn_ti												MetaCyc:RXN-8936		molecular_function											owl:Class	
GO:0060580	biolink:NamedThing	ventral spinal cord interneuron fate determination	The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.	got7fsn_ti							dph	2009-05-07T12:24:50Z						biological_process											owl:Class	
GO:0097452	biolink:NamedThing	GAIT complex	A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP.	got7fsn_ti	gamma interferon-activated inhibitor of translation complex|IFN-gamma-activated inhibitor of translation complex						pr	2012-12-19T09:32:25Z						cellular_component											owl:Class	
GO:0005881	biolink:NamedThing	cytoplasmic microtubule	Any microtubule in the cytoplasm of a cell.	got7fsn_ti	non-spindle-associated astral microtubule													cellular_component											owl:Class	
GO:0042671	biolink:NamedThing	retinal cone cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0120035	biolink:NamedThing	regulation of plasma membrane bounded cell projection organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13298					krc	2017-04-26T16:02:06Z						biological_process											owl:Class	
GO:0031344	biolink:NamedThing	regulation of cell projection organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.	got7fsn_ti	regulation of cell projection organisation|regulation of cell projection organization and biogenesis													biological_process											owl:Class	
GO:0050382	biolink:NamedThing	uracil-5-carboxylate decarboxylase activity	Catalysis of the reaction: H(+) + uracil 5-carboxylate = CO(2) + uracil.	got7fsn_ti	uracil-5-carboxylate carboxy-lyase activity|uracil-5-carboxylate carboxy-lyase (uracil-forming)|uracil-5-carboxylic acid decarboxylase activity											KEGG_REACTION:R00973|RHEA:17685|EC:4.1.1.66|MetaCyc:URACIL-5-CARBOXYLATE-DECARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0042595	biolink:NamedThing	behavioral response to starvation	Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment.	got7fsn_ti	behavioural response to starvation													biological_process											owl:Class	
GO:0061767	biolink:NamedThing	negative regulation of lung blood pressure	The process that decreases the force with which blood travels through the lungs.	got7fsn_ti	negative regulation of pulmonary blood pressure						dph	2016-04-27T11:58:55Z						biological_process											owl:Class	
GO:0014916	biolink:NamedThing	regulation of lung blood pressure	The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.	got7fsn_ti	regulation of pulmonary blood pressure													biological_process											owl:Class	
GO:0010853	biolink:NamedThing	cyclase activator activity	Increases the activity of an enzyme that catalyzes a ring closure reaction.	got7fsn_ti														molecular_function											owl:Class	
GO:0010851	biolink:NamedThing	cyclase regulator activity	Binds to and modulates the activity of an enzyme that catalyzes a ring closure reaction.	got7fsn_ti														molecular_function											owl:Class	
GO:0000488	biolink:NamedThing	maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0035655	biolink:NamedThing	interleukin-18-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-18-mediated signalling pathway						bf	2011-01-26T09:55:57Z						biological_process											owl:Class	
GO:0102295	biolink:NamedThing	4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity	Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA <=> 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A.	got7fsn_ti												MetaCyc:RXN-12699		molecular_function											owl:Class	
GO:0050465	biolink:NamedThing	nitroquinoline-N-oxide reductase activity	Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+.	got7fsn_ti	4-nitroquinoline 1-oxide reductase activity|4NQO reductase activity|NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase activity|4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase activity|NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity											MetaCyc:1.7.1.9-RXN|EC:1.7.1.9		molecular_function											owl:Class	
GO:0003140	biolink:NamedThing	determination of left/right asymmetry in lateral mesoderm	The establishment of the lateral mesoderm with respect to the left and right halves.	got7fsn_ti							tb	2009-09-22T03:58:29Z						biological_process											owl:Class	
GO:0003877	biolink:NamedThing	ATP adenylyltransferase activity	Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate.	got7fsn_ti	adenine triphosphate adenylyltransferase activity|diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase activity|AP-4-A phosphorylase activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase activity|diadenosinetetraphosphate alphabeta-phosphorylase activity|dinucleoside oligophosphate alphabeta-phosphorylase activity|ADP:ATP adenylyltransferase activity|diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming)|diadenosinetetraphosphate alpha-beta-phosphorylase activity|bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming) activity											MetaCyc:ATP-ADENYLYLTRANSFERASE-RXN|RHEA:16577|EC:2.7.7.53		molecular_function											owl:Class	
GO:0050423	biolink:NamedThing	thiamine oxidase activity	Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.	got7fsn_ti	thiamine dehydrogenase activity|thiamin:oxygen 5-oxidoreductase activity|thiamine:oxygen 5-oxidoreductase activity|thiamin oxidase activity|thiamin dehydrogenase activity											MetaCyc:THIAMIN-OXIDASE-RXN|EC:1.1.3.23|RHEA:21280		molecular_function											owl:Class	
GO:0097512	biolink:NamedThing	cardiac myofibril	A cardiac myofibril is a myofibril specific to cardiac muscle cells.	got7fsn_ti							pr	2013-10-16T13:04:58Z						cellular_component											owl:Class	
GO:1990245	biolink:NamedThing	histone H2A-T120 phosphorylation	The modification of histone H2A by the addition of a phosphate group to a threonine residue at position 120 of the histone.	got7fsn_ti	histone H2AT120 phosphorylation|histone H2A phosphorylation at T120						sp	2013-12-04T06:41:30Z						biological_process											owl:Class	
GO:0021927	biolink:NamedThing	deep nuclear neuron precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0044196	biolink:NamedThing	host cell nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic host cells.	got7fsn_ti							jl	2009-10-20T02:37:07Z						cellular_component											owl:Class	
GO:0061738	biolink:NamedThing	late endosomal microautophagy	The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.	got7fsn_ti							dph	2015-09-24T14:40:02Z						biological_process											owl:Class	
GO:0018615	biolink:NamedThing	2-indanone monooxygenase activity	Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone.	got7fsn_ti												UM-BBD_reactionID:r0424|EC:1.14.12.-		molecular_function											owl:Class	
GO:0007315	biolink:NamedThing	pole plasm assembly	Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster.	got7fsn_ti											GO:0048113			biological_process											owl:Class	
GO:0070739	biolink:NamedThing	protein-glutamic acid ligase activity	Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein.	got7fsn_ti	protein-glutamate ligase activity|protein glutamylase activity						mah	2009-06-19T02:23:22Z						molecular_function											owl:Class	
GO:0018057	biolink:NamedThing	peptidyl-lysine oxidation	The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.	got7fsn_ti												RESID:AA0121		biological_process											owl:Class	
GO:0019589	biolink:NamedThing	anaerobic glycerol catabolic process to propane-1,3-diol	The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water.	got7fsn_ti	glycerol fermentation to 1,3-propanediol|glycerol fermentation to propane-1,3-diol											MetaCyc:GOLPDLCAT-PWY		biological_process											owl:Class	
GO:0019588	biolink:NamedThing	anaerobic glycerol catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP.	got7fsn_ti	glycerol fermentation													biological_process											owl:Class	
GO:0031102	biolink:NamedThing	neuron projection regeneration	The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.	got7fsn_ti	neurite regeneration													biological_process											owl:Class	
GO:0033691	biolink:NamedThing	sialic acid binding	Binding to a sialic acid, a N- or O- substituted derivative of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.	got7fsn_ti	N-acetylneuraminic acid binding													molecular_function											owl:Class	
GO:0102625	biolink:NamedThing	cirsimaritin 4'-O-methyltransferase activity	Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine  <=> salvigenin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-15530		molecular_function											owl:Class	
GO:0031100	biolink:NamedThing	animal organ regeneration	The regrowth of a lost or destroyed animal organ.	got7fsn_ti														biological_process											owl:Class	
GO:0045748	biolink:NamedThing	positive regulation of R8 cell spacing in compound eye	Any process that activates or enforces the correct R8 cell spacing in a compound eye.	got7fsn_ti	upregulation of R8 spacing|up regulation of R8 spacing|up-regulation of R8 spacing|stimulation of R8 spacing|positive regulation of R8 spacing|activation of R8 spacing													biological_process											owl:Class	
GO:0070168	biolink:NamedThing	negative regulation of biomineral tissue development	Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.	got7fsn_ti														biological_process											owl:Class	
GO:0080067	biolink:NamedThing	4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate.	got7fsn_ti							dhl	2009-04-13T04:05:53Z				MetaCyc:RXNQT-4329		molecular_function											owl:Class	
GO:0102636	biolink:NamedThing	3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine gamma-glutamylcyclotransferase activity	Catalysis of the reaction: 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine <=> 3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine + 2 5-oxo-L-prolinate.	got7fsn_ti												MetaCyc:RXN-15681		molecular_function											owl:Class	
GO:0098685	biolink:NamedThing	Schaffer collateral - CA1 synapse	A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.	got7fsn_ti							dos	2017-02-05T16:29:43Z						cellular_component											owl:Class	
GO:0090429	biolink:NamedThing	detection of endogenous biotic stimulus	The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti							tb	2012-05-11T09:19:39Z						biological_process											owl:Class	
GO:0000297	biolink:NamedThing	spermine transmembrane transporter activity	Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.	got7fsn_ti														molecular_function											owl:Class	
GO:0015203	biolink:NamedThing	polyamine transmembrane transporter activity	Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.	got7fsn_ti	amine/amide/polyamine channel activity													molecular_function											owl:Class	
GO:0060076	biolink:NamedThing	excitatory synapse	A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.	got7fsn_ti												Wikipedia:Excitatory_synapse		cellular_component											owl:Class	
GO:1904072	biolink:NamedThing	presynaptic active zone disassembly	The disaggregation of a presynaptic active zone into its constituent components.	got7fsn_ti	pre-synaptic active zone component disassembly|pre-synaptic active zone disassembly						pr	2015-03-20T10:36:33Z						biological_process											owl:Class	
GO:0050217	biolink:NamedThing	propioin synthase activity	Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal.	got7fsn_ti	4-hydroxy-3-hexanone propanal-lyase (propanal-forming)|4-hydroxy-3-hexanone aldolase activity|4-hydroxy-3-hexanone propanal-lyase activity											EC:4.1.2.35|RHEA:11100|KEGG_REACTION:R00038|MetaCyc:PROPIOIN-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0070009	biolink:NamedThing	serine-type aminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681												molecular_function											owl:Class	
GO:0070008	biolink:NamedThing	serine-type exopeptidase activity	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	got7fsn_ti												EC:3.4.21.-		molecular_function											owl:Class	
GO:0034146	biolink:NamedThing	toll-like receptor 5 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 5.	got7fsn_ti	toll-like receptor 5 signalling pathway|TLR5 signaling pathway													biological_process											owl:Class	
GO:0044171	biolink:NamedThing	host cell smooth endoplasmic reticulum membrane	The lipid bilayer surrounding the host cell smooth endoplasmic reticulum.	got7fsn_ti	host smooth endoplasmic reticulum membrane						jl	2009-09-04T11:46:00Z						cellular_component											owl:Class	
GO:0009303	biolink:NamedThing	rRNA transcription	The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.	got7fsn_ti	rRNA biosynthetic process|rRNA synthesis|rRNA biosynthesis													biological_process											owl:Class	
GO:0043974	biolink:NamedThing	histone H3-K27 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone.	got7fsn_ti	histone H3K27 acetylation|histone H3 acetylation at K27													biological_process											owl:Class	
GO:0060474	biolink:NamedThing	positive regulation of flagellated sperm motility involved in capacitation	The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.	got7fsn_ti	positive regulation of sperm motility involved in capacitation													biological_process											owl:Class	
GO:0009040	biolink:NamedThing	ureidoglycolate dehydrogenase activity	Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+.	got7fsn_ti	(S)-ureidoglycolate:NAD(P)+ oxidoreductase activity											MetaCyc:R165-RXN|EC:1.1.1.154		molecular_function											owl:Class	
GO:0080075	biolink:NamedThing	spermidine:feruloyl CoA N-acyltransferase activity	Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule.	got7fsn_ti							dhl	2009-04-13T04:17:50Z						molecular_function											owl:Class	
GO:0140367	biolink:NamedThing	antibacterial innate immune response	An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti							pg	2019-09-09T11:02:47Z						biological_process											owl:Class	
GO:0097061	biolink:NamedThing	dendritic spine organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.	got7fsn_ti	dendritic spine organisation						pr	2011-06-07T11:26:53Z						biological_process											owl:Class	
GO:0003837	biolink:NamedThing	beta-ureidopropionase activity	Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3.	got7fsn_ti	N-carbamoyl-beta-alanine amidohydrolase activity											RHEA:11184|Reactome:R-HSA-73591|EC:3.5.1.6|Reactome:R-HSA-73620|MetaCyc:BETA-UREIDOPROPIONASE-RXN		molecular_function											owl:Class	
GO:0048785	biolink:NamedThing	hatching gland development	The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process.	got7fsn_ti														biological_process											owl:Class	
GO:0150001	biolink:NamedThing	primary dendrite	A dendrite emerging from the cell body (the soma) of a neuron.	got7fsn_ti														cellular_component											owl:Class	
GO:0048311	biolink:NamedThing	mitochondrion distribution	Any process that establishes the spatial arrangement of mitochondria between and within cells.	got7fsn_ti	positioning of mitochondria|distribution of mitochondria|mitochondrial distribution													biological_process											owl:Class	
GO:0051646	biolink:NamedThing	mitochondrion localization	Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	localization of mitochondrion|localization of mitochondria|mitochondrial localization|establishment and maintenance of mitochondria localization|establishment and maintenance of mitochondrion localization|mitochondria localization|mitochondrion localisation													biological_process											owl:Class	
GO:0045322	biolink:NamedThing	unmethylated CpG binding	Binding to uan nmethylated CpG motif. Unmethylated CpG dinucleotides are often associated with gene promoters.	got7fsn_ti														molecular_function											owl:Class	
GO:0033361	biolink:NamedThing	lysine biosynthetic process via diaminopimelate, dehydrogenase pathway	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step.	got7fsn_ti	lysine biosynthesis via diaminopimelic acid, dehydrogenase pathway|lysine anabolism via diaminopimelate, dehydrogenase pathway|lysine synthesis via diaminopimelate, dehydrogenase pathway|lysine formation via diaminopimelate, dehydrogenase pathway											MetaCyc:PWY-2942		biological_process											owl:Class	
GO:0009089	biolink:NamedThing	lysine biosynthetic process via diaminopimelate	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.	got7fsn_ti	lysine biosynthetic process via diaminopimelic acid|lysine synthesis via diaminopimelate|diaminopimelic acid pathway|diaminopimelate pathway|lysine formation via diaminopimelate|lysine biosynthesis via diaminopimelic acid|lysine anabolism via diaminopimelate													biological_process											owl:Class	
GO:0007175	biolink:NamedThing	negative regulation of epidermal growth factor-activated receptor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.	got7fsn_ti	negative regulation of epidermal growth factor receptor activity|EGF receptor downregulation|inhibition of epidermal growth factor receptor activity|down-regulation of epidermal growth factor receptor activity|negative regulation of EGF receptor activity|down regulation of epidermal growth factor receptor activity|downregulation of epidermal growth factor receptor activity|negative regulation of EGFR activity										GO:0007177			biological_process											owl:Class	
GO:0018507	biolink:NamedThing	cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity	Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol.	got7fsn_ti	cis-3,4-dihydroxy-3,4-dihydrophenanthrene dehydrogenase activity|(+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase activity											EC:1.3.1.49|MetaCyc:1.3.1.49-RXN|KEGG_REACTION:R04151|RHEA:16253|UM-BBD_reactionID:r0488		molecular_function											owl:Class	
GO:0034453	biolink:NamedThing	microtubule anchoring	Any process in which a microtubule is maintained in a specific location in a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0047416	biolink:NamedThing	arylalkyl acylamidase activity	Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine.	got7fsn_ti	aralkyl acylamidase activity|N-acetylarylalkylamine amidohydrolase activity											EC:3.5.1.76|RHEA:10352|MetaCyc:3.5.1.76-RXN		molecular_function											owl:Class	
GO:0048478	biolink:NamedThing	replication fork protection	Any process that prevents the collapse of stalled replication forks.	got7fsn_ti	replication fork maintenance|replication fork stabilization													biological_process											owl:Class	
GO:2000104	biolink:NamedThing	negative regulation of DNA-dependent DNA replication	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.	got7fsn_ti							mah	2010-09-15T01:37:05Z						biological_process											owl:Class	
GO:0017101	biolink:NamedThing	aminoacyl-tRNA synthetase multienzyme complex	A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates.	got7fsn_ti	aminoacyl-tRNA synthetase complex|multisynthetase complex													cellular_component											owl:Class	
GO:0071852	biolink:NamedThing	fungal-type cell wall organization or biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.	got7fsn_ti	fungal-type cell wall organization and biogenesis|fungal-type cell wall organisation or biogenesis						mah	2010-09-10T03:07:55Z						biological_process											owl:Class	
GO:0097044	biolink:NamedThing	histone H3-K56 acetylation in response to DNA damage	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone as a result of the detection of DNA damage within a cell.	got7fsn_ti							pr	2011-04-19T05:22:54Z						biological_process											owl:Class	
GO:0031759	biolink:NamedThing	Edg-6 sphingosine 1-phosphate receptor binding	Binding to an Edg-6 sphingosine 1-phosphate receptor.	got7fsn_ti	Edg-6 sphingosine 1-phosphate receptor ligand													molecular_function											owl:Class	
GO:0016414	biolink:NamedThing	O-octanoyltransferase activity	Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0008281	biolink:NamedThing	sulfonylurea receptor activity	Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	sulphonylurea receptor activity				Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'potassium channel activity ; GO:0005267'.									molecular_function											owl:Class	
GO:0052368	biolink:NamedThing	disruption by organism of cellular component in other organism involved in symbiotic interaction	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism of cellular component in other organism|disassembly by organism of cellular component in other organism during symbiotic interaction|catabolism of structural constituent in other organism|degradation of cellular component in other organism|disassembly by organism of cellular component in other organism involved in symbiotic interaction													biological_process											owl:Class	
GO:0044552	biolink:NamedThing	vasodilation in other organism	A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism.	got7fsn_ti	regulation of vasodilation in other organism|modulation of vasodilation in other organism						jl	2012-03-29T02:14:42Z						biological_process											owl:Class	
GO:0034894	biolink:NamedThing	4-hydroxypyridine-3-hydroxylase activity	Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+.	got7fsn_ti												UM-BBD_reactionID:r1397|EC:1.14.13.-		molecular_function											owl:Class	
GO:0080018	biolink:NamedThing	anthocyanin 5-O-glucosyltransferase activity	Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP.	got7fsn_ti														molecular_function											owl:Class	
GO:0098831	biolink:NamedThing	presynaptic active zone cytoplasmic component	A specialized region below the presynaptic membrane, characterized by electron-dense material, a specialized cytoskeletal matrix and accumulated (associated) synaptic vesicles.	got7fsn_ti	presynaptic zone cortex|cortex of presynaptic active zone													cellular_component											owl:Class	
GO:0045948	biolink:NamedThing	positive regulation of translational initiation	Any process that activates or increases the frequency, rate or extent of translational initiation.	got7fsn_ti	stimulation of translational initiation|up-regulation of translational initiation|activation of translational initiation|up regulation of translational initiation|upregulation of translational initiation													biological_process											owl:Class	
GO:0034878	biolink:NamedThing	2-hydroxyisonicotinate dehydrogenase activity	Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor.	got7fsn_ti												UM-BBD_reactionID:r1338		molecular_function											owl:Class	
GO:0046741	biolink:NamedThing	transport of virus in host, tissue to tissue	The transport of a virus between tissues in a multicellular organism.	got7fsn_ti	spread of virus within host, tissue to tissue|spread of virus in host, tissue to tissue|viral spread within host, tissue to tissue|tissue to tissue spread of virus within host													biological_process											owl:Class	
GO:2001231	biolink:NamedThing	regulation of protein localization to prospore membrane	Any process that modulates the frequency, rate or extent of protein localization to prospore membrane.	got7fsn_ti	regulation of protein targeting to forespore membrane|regulation of protein localisation to prospore membrane|regulation of protein targeting to FSM|regulation of protein targeting to prospore membrane|regulation of protein targeting to ascospore-type prospore membrane|regulation of protein-prospore membrane targeting						mah	2011-11-21T04:13:30Z						biological_process											owl:Class	
GO:1903076	biolink:NamedThing	regulation of protein localization to plasma membrane	Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.	got7fsn_ti	regulation of protein targeting to plasma membrane|regulation of establishment of protein localisation in plasma membrane|regulation of establishment of protein localization in plasma membrane|regulation of protein localization in plasma membrane|regulation of protein-plasma membrane targeting|regulation of establishment of protein localization to plasma membrane|regulation of protein localisation in plasma membrane						tb	2009-07-10T10:32:44Z			GO:0090003|GO:1905963			biological_process											owl:Class	
GO:1990526	biolink:NamedThing	Ste12p-Dig1p-Dig2p complex	A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae.	got7fsn_ti							rb	2014-11-05T22:49:32Z						cellular_component											owl:Class	
GO:0072503	biolink:NamedThing	cellular divalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell.	got7fsn_ti					Note that this term was split from 'cellular di-, tri-valent inorganic cation homeostasis ; GO:0030005' (sibling term 'cellular trivalent inorganic cation homeostasis' ; GO:0072504').		mah	2010-12-16T01:25:40Z						biological_process											owl:Class	
GO:0099507	biolink:NamedThing	ligand-gated ion channel activity involved in regulation of presynaptic membrane potential	Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.	got7fsn_ti	ligand-dependent ion channel activity involved in regulation of pre-synaptic membrane potential|ligand-gated ion channel activity involved in regulation of pre-synaptic membrane potential|ligand-dependent ion channel activity involved in regulation of presynaptic membrane potential|ligand gated ion channel activity involved in regulation of presynaptic membrane potential													molecular_function											owl:Class	
GO:0015476	biolink:NamedThing	hemaglutinin autotransporter activity	Enables the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively.	got7fsn_ti														molecular_function											owl:Class	
GO:0019062	biolink:NamedThing	virion attachment to host cell	The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.	got7fsn_ti	virion attachment to host cell surface receptor|viral attachment to host cell|viral absorption											VZ:956		biological_process											owl:Class	
GO:0018810	biolink:NamedThing	trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity	Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene.	got7fsn_ti												UM-BBD_reactionID:r0164		molecular_function											owl:Class	
GO:0098582	biolink:NamedThing	innate vocalization behavior	A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.	got7fsn_ti							dos	2014-01-24T12:47:01Z						biological_process											owl:Class	
GO:0052729	biolink:NamedThing	dimethylglycine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.	got7fsn_ti	ApDMT|S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity						ai	2011-08-16T03:45:16Z				EC:2.1.1.162|MetaCyc:R482-RXN|MetaCyc:RXN-9680|EC:2.1.1.161|KEGG_REACTION:R07244|RHEA:10072|EC:2.1.1.157		molecular_function											owl:Class	
GO:0051986	biolink:NamedThing	negative regulation of attachment of spindle microtubules to kinetochore	Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.	got7fsn_ti	inhibition of attachment of spindle microtubules to kinetochore|downregulation of attachment of spindle microtubules to kinetochore|down-regulation of attachment of spindle microtubules to kinetochore|down regulation of attachment of spindle microtubules to kinetochore													biological_process											owl:Class	
GO:0051985	biolink:NamedThing	negative regulation of chromosome segregation	Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.	got7fsn_ti	inhibition of chromosome segregation|down-regulation of chromosome segregation|down regulation of chromosome segregation|downregulation of chromosome segregation													biological_process											owl:Class	
GO:0006618	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane, signal sequence processing	The removal of the signal peptide from a nascent protein during cotranslational membrane targeting.	got7fsn_ti	SRP-dependent cotranslational protein-membrane targeting, signal sequence processing|signal sequence processing during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, signal sequence processing													biological_process											owl:Class	
GO:0008482	biolink:NamedThing	sulfite oxidase activity	Catalysis of the reaction: H(2)O + O(2) + sulfite = H(2)O(2) + H(+) + sulfate.	got7fsn_ti	sulfite:oxygen oxidoreductase activity|sulphite oxidase activity											MetaCyc:SULFITE-OXIDASE-RXN|EC:1.8.3.1|RHEA:24600|Reactome:R-HSA-1614544|MetaCyc:PWY-5326|KEGG_REACTION:R00533		molecular_function											owl:Class	
GO:1902178	biolink:NamedThing	fibroblast growth factor receptor apoptotic signaling pathway	An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR).	got7fsn_ti	fibroblast growth factor receptor signaling pathway involved in apoptotic process|fibroblast growth factor receptor signaling pathway involved in apoptotic programmed cell death|FGF receptor signalling pathway involved in apoptotic cell death|FGF receptor signaling pathway involved in apoptotic process|FGFR signaling pathway involved in apoptotic program|fibroblast growth factor receptor signalling pathway involved in apoptotic programmed cell death|FGF receptor signaling pathway involved in type I programmed cell death|FGFR signaling pathway involved in programmed cell death by apoptosis|FGFR signaling pathway involved in signaling (initiator) caspase activity|fibroblast growth factor receptor signalling pathway involved in apoptosis|FGF receptor signalling pathway involved in apoptotic program|FGFR signaling pathway involved in apoptotic cell death|FGFR signaling pathway involved in apoptosis|FGF receptor signaling pathway involved in signaling (initiator) caspase activity|fibroblast growth factor receptor signalling pathway involved in signaling (initiator) caspase activity|FGFR signaling pathway involved in apoptotic process|FGF receptor signaling pathway involved in programmed cell death by apoptosis|FGF receptor signalling pathway involved in programmed cell death by apoptosis|FGF receptor signalling pathway involved in apoptotic programmed cell death|fibroblast growth factor receptor signaling pathway involved in apoptotic program|FGFR signaling pathway involved in apoptotic programmed cell death|fibroblast growth factor receptor signaling pathway involved in signaling (initiator) caspase activity|fibroblast growth factor receptor signaling pathway involved in type I programmed cell death|fibroblast growth factor receptor signalling pathway involved in programmed cell death by apoptosis|fibroblast growth factor receptor signalling pathway involved in type I programmed cell death|FGF receptor signaling pathway involved in apoptotic program|FGFR signaling pathway involved in type I programmed cell death|FGF receptor signaling pathway involved in apoptotic cell death|fibroblast growth factor receptor signalling pathway involved in apoptotic cell death|FGF receptor signaling pathway involved in apoptosis|FGF receptor signalling pathway involved in apoptotic process|fibroblast growth factor receptor signaling pathway involved in programmed cell death by apoptosis|fibroblast growth factor receptor signaling pathway involved in apoptotic cell death|FGF receptor signalling pathway involved in type I programmed cell death|fibroblast growth factor receptor signaling pathway involved in apoptosis|fibroblast growth factor receptor signalling pathway involved in apoptotic process|FGF receptor signaling pathway involved in apoptotic programmed cell death|FGF receptor signalling pathway involved in signaling (initiator) caspase activity|FGF receptor signalling pathway involved in apoptosis|fibroblast growth factor receptor signalling pathway involved in apoptotic program						pm	2013-05-30T13:59:57Z						biological_process											owl:Class	
GO:0102845	biolink:NamedThing	1-18:3-2-16:0-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8307		molecular_function											owl:Class	
GO:0097356	biolink:NamedThing	perinucleolar compartment	The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC.	got7fsn_ti	perinucleolar region						pr	2012-07-03T05:11:01Z						cellular_component											owl:Class	
GO:0140222	biolink:NamedThing	pathogen-containing vacuole lumen	The enclosed volume within the sealed membrane of a pathogen-containing vacuole.	got7fsn_ti	lumen of a pathogen-containing vacuole|pathogen-containing vacuolar lumen|pathogen-containing compartment lumen|pathogen inclusion lumen	https://github.com/geneontology/go-ontology/issues/15580					pg	2018-04-20T06:24:02Z						cellular_component											owl:Class	
GO:0060176	biolink:NamedThing	regulation of aggregation involved in sorocarp development	Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.	got7fsn_ti														biological_process											owl:Class	
GO:0019099	biolink:NamedThing	female germ-line sex determination	The determination of sex and sexual phenotype in a female organism's germ line.	got7fsn_ti	sex determination, female germ-line determination										GO:0007544			biological_process											owl:Class	
GO:0007542	biolink:NamedThing	primary sex determination, germ-line	The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line.	got7fsn_ti														biological_process											owl:Class	
GO:0034385	biolink:NamedThing	triglyceride-rich plasma lipoprotein particle	A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood.	got7fsn_ti	triglyceride-rich lipoprotein particle|triacylglycerol-rich lipoprotein particle													cellular_component											owl:Class	
GO:0099513	biolink:NamedThing	polymeric cytoskeletal fiber	A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.	got7fsn_ti														cellular_component											owl:Class	
GO:0001855	biolink:NamedThing	complement component C4b binding	Binding to a C4b product of the classical complement cascade.	got7fsn_ti														molecular_function											owl:Class	
GO:0072281	biolink:NamedThing	mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti							mah	2010-04-01T03:22:06Z						biological_process											owl:Class	
GO:0004135	biolink:NamedThing	amylo-alpha-1,6-glucosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.	got7fsn_ti	dextrin 6-alpha-D-glucosidase activity|glycogen phosphorylase-limit dextrin alpha-1,6-glucohydrolase activity|amylo-1,6-glucosidase activity|dextrin-1,6-glucosidase activity|amylopectin 1,6-glucosidase activity											EC:3.2.1.33|Reactome:R-HSA-71593|MetaCyc:3.2.1.33-RXN		molecular_function											owl:Class	
GO:1990799	biolink:NamedThing	mitochondrial tRNA wobble position uridine thiolation	The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.	got7fsn_ti							vw	2015-07-13T08:15:15Z						biological_process											owl:Class	
GO:0034075	biolink:NamedThing	arabidiol synthase activity	Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).	got7fsn_ti												EC:4.2.1.124|RHEA:31035|MetaCyc:RXN-9684		molecular_function											owl:Class	
GO:0036424	biolink:NamedThing	L-phosphoserine phosphatase activity	Catalysis of the reaction: O-phospho-L-serine + H2O = L-serine + phosphate, on a free amino acid.	got7fsn_ti	phosphoserine phosphatase activity|O-phosphoserine phosphohydrolase activity	https://github.com/geneontology/go-ontology/issues/21638|https://github.com/geneontology/go-ontology/issues/20587			Do not confuse with protein phosphatases. For protein phosphatases, consider GO:0004722 ; protein serine/threonine phosphatase activity or GO:0008138 ; protein tyrosine/serine/threonine phosphatase activity.		bf	2013-09-16T13:01:03Z			GO:0004647	EC:3.1.3.3|MetaCyc:PSERPHOSPHA-RXN|MetaCyc:RXN0-5114|RHEA:21208|Reactome:R-HSA-977324|KEGG_REACTION:R00582		molecular_function											owl:Class	
GO:0051272	biolink:NamedThing	positive regulation of cellular component movement	Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.	got7fsn_ti	positive regulation of cellular component motion													biological_process											owl:Class	
GO:0071424	biolink:NamedThing	rRNA (cytosine-N4-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine.	got7fsn_ti							mah	2009-12-15T03:46:52Z						molecular_function											owl:Class	
GO:0032182	biolink:NamedThing	ubiquitin-like protein binding	Binding to a small conjugating protein such as ubiquitin or a ubiquitin-like protein.	got7fsn_ti	small conjugating protein binding													molecular_function											owl:Class	
GO:0102552	biolink:NamedThing	lipoyl synthase activity (acting on glycine-cleavage complex H protein	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine  + 2 5'-deoxyadenosine + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier].	got7fsn_ti												EC:2.8.1.8|MetaCyc:RXN-14950		molecular_function											owl:Class	
GO:0015074	biolink:NamedThing	DNA integration	The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.	got7fsn_ti														biological_process											owl:Class	
GO:0004587	biolink:NamedThing	ornithine-oxo-acid transaminase activity	Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.	got7fsn_ti	ornithine--alpha-ketoglutarate aminotransferase activity|ornithine transaminase activity|ornithine-oxo-acid aminotransferase activity|ornithine--oxo acid aminotransferase activity|GabT|L-ornithine:2-oxo-acid aminotransferase activity|ornithine--keto acid aminotransferase activity|ornithine--ketoglutarate aminotransferase activity|ornithine ketoacid aminotransferase activity|ornithine delta-transaminase activity|OAT|ornithine 5-aminotransferase activity|ornithine--oxo-acid transaminase activity|L-ornithine:alpha-ketoglutarate delta-aminotransferase activity|ornithine:alpha-oxoglutarate transaminase activity|ornithine--keto acid transaminase activity|ornithine aminotransferase activity|L-ornithine aminotransferase activity|L-ornithine 5-aminotransferase activity|ornithine--2-oxoacid aminotransferase activity											EC:2.6.1.13|Reactome:R-HSA-70654|RHEA:13877|Reactome:R-HSA-70666|MetaCyc:ORNITHINE--OXO-ACID-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:2000693	biolink:NamedThing	positive regulation of seed maturation	Any process that activates or increases the frequency, rate or extent of seed maturation.	got7fsn_ti							dhl	2011-05-13T06:41:46Z						biological_process											owl:Class	
GO:0022831	biolink:NamedThing	narrow pore, gated channel activity	Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus.	got7fsn_ti	ion channels											Wikipedia:Ion_channels		molecular_function											owl:Class	
GO:0022842	biolink:NamedThing	narrow pore channel activity	Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated.	got7fsn_ti														molecular_function											owl:Class	
GO:0098597	biolink:NamedThing	observational learning	Learning that occurs through observing the behavior of others.	got7fsn_ti					Observation here is used in a broad sense to include perception of the behavior of others via any form or combination of forms of sensory perception (visual, auditory etc). Observational learning is broader than imitative learning in that it does not require a duplication of the behavior exhibited by the model.		dos	2014-04-10T11:07:10Z				Wikipedia:Observational_learning		biological_process											owl:Class	
GO:0050196	biolink:NamedThing	[phosphorylase] phosphatase activity	Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate.	got7fsn_ti	PR-enzyme|phosphorylase a phosphohydrolase activity|type 1 protein phosphatase activity|phosphorylase a phosphatase activity|glycogen phosphorylase phosphatase activity|phosphorylase phosphatase activity|protein phosphatase C											EC:3.1.3.17|MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:1900125	biolink:NamedThing	regulation of hyaluronan biosynthetic process	Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process.	got7fsn_ti	regulation of hyaluronan biosynthesis|regulation of hyaluronan synthesis|regulation of hyaluronan anabolism|regulation of hyaluronan formation						yaf	2012-02-23T01:09:21Z						biological_process											owl:Class	
GO:0042309	biolink:NamedThing	homoiothermy	Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment.	got7fsn_ti	ice nucleation activity|antifreeze activity|ice nucleation inhibitor activity													biological_process											owl:Class	
GO:0003831	biolink:NamedThing	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.	got7fsn_ti	glycoprotein 4-beta-galactosyl-transferase activity|GalT activity|thyroid glycoprotein beta-galactosyltransferase|uridine diphosphogalactose-glycoprotein galactosyltransferase activity|UDP-galactose--glycoprotein galactosyltransferase activity|thyroid galactosyltransferase activity|glycoprotein beta-galactosyltransferase activity|beta-N-acetyl-beta-(1,4)-galactosyltransferase activity|glycoprotein 4-beta-galactosyltransferase activity|beta-N-acetyl-beta-1,4-galactosyltransferase activity|UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity|UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity|UDPgalactose-glycoprotein galactosyltransferase activity											Reactome:R-HSA-975919|Reactome:R-HSA-2046298|Reactome:R-HSA-1912352|Reactome:R-HSA-4793956|Reactome:R-HSA-2046265|Reactome:R-HSA-9035949|RHEA:22932|Reactome:R-HSA-2025723|MetaCyc:2.4.1.38-RXN|EC:2.4.1.38|Reactome:R-HSA-3656230|Reactome:R-HSA-9035950		molecular_function											owl:Class	
GO:0030562	biolink:NamedThing	rRNA 2'-O-ribose methylation guide activity	Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0030556	biolink:NamedThing	rRNA modification guide activity	Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0102406	biolink:NamedThing	omega-hydroxypalmitate O-sinapoyl transferase activity	Catalysis of the reaction: sinapoyl-CoA + 16-hydroxypalmitate <=> coenzyme A + 16-sinapoyloxypalmitate.	got7fsn_ti												RHEA:26470|EC:2.3.1.188|MetaCyc:RXN-13728		molecular_function											owl:Class	
GO:0034154	biolink:NamedThing	toll-like receptor 7 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 7.	got7fsn_ti	toll-like receptor 7 signalling pathway|TLR7 signaling pathway													biological_process											owl:Class	
GO:0072260	biolink:NamedThing	metanephric interstitial fibroblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast.	got7fsn_ti	metanephros interstitial cell fate commitment						mah	2010-03-19T04:18:10Z						biological_process											owl:Class	
GO:0072153	biolink:NamedThing	renal interstitial fibroblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast.	got7fsn_ti	kidney interstitial cell fate commitment						mah	2010-02-24T02:16:53Z						biological_process											owl:Class	
GO:0030538	biolink:NamedThing	embryonic genitalia morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized.	got7fsn_ti	embryonic genital morphogenesis													biological_process											owl:Class	
GO:0070559	biolink:NamedThing	lysosomal multienzyme complex	A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism.	got7fsn_ti	GALNS-lysosomal hydrolase 1.27 MDa complex													cellular_component											owl:Class	
GO:0030309	biolink:NamedThing	poly-N-acetyllactosamine metabolic process	The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.	got7fsn_ti	poly-N-acetyllactosamine metabolism													biological_process											owl:Class	
GO:0050872	biolink:NamedThing	white fat cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.	got7fsn_ti	white adipocyte cell differentiation|white adipocyte differentiation													biological_process											owl:Class	
GO:0045444	biolink:NamedThing	fat cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.	got7fsn_ti	adipocyte cell differentiation|adipocyte differentiation|adipogenesis|adipose cell differentiation													biological_process											owl:Class	
GO:0018413	biolink:NamedThing	peptidyl-serine O-glucuronidation	The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine.	got7fsn_ti												RESID:AA0291		biological_process											owl:Class	
GO:0018412	biolink:NamedThing	protein O-glucuronidation	The modification of a protein by glucuronidation on an amino acid oxygen atom.	got7fsn_ti	protein amino acid O-glucuronidation													biological_process											owl:Class	
GO:0015851	biolink:NamedThing	nucleobase transport	The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	nucleobase transmembrane transport													biological_process											owl:Class	
GO:0018572	biolink:NamedThing	3,5-dichlorocatechol 1,2-dioxygenase activity	Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0276		molecular_function											owl:Class	
GO:0051776	biolink:NamedThing	detection of redox state	The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.	got7fsn_ti	redox sensing													biological_process											owl:Class	
GO:0102245	biolink:NamedThing	lupan-3beta,20-diol synthase activity	Catalysis of the reaction: lupan-3beta,20-diol <=> (S)-2,3-epoxysqualene + H2O.	got7fsn_ti												EC:4.2.1.128|RHEA:31351|MetaCyc:RXN-12338		molecular_function											owl:Class	
GO:0020015	biolink:NamedThing	glycosome	A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.	got7fsn_ti												Wikipedia:Glycosome		cellular_component											owl:Class	
GO:0098037	biolink:NamedThing	viral DNA genome packaging, 5' extended cos packaging	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends.	got7fsn_ti							bm	2012-07-20T11:40:47Z						biological_process											owl:Class	
GO:0031638	biolink:NamedThing	zymogen activation	The proteolytic processing of an inactive enzyme to an active form.	got7fsn_ti	zymogen activation by proteolytic cleavage													biological_process											owl:Class	
GO:0060107	biolink:NamedThing	annuli extracellular matrix	The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present.	got7fsn_ti	annulus|annulae|annule(s)|annular rings													cellular_component											owl:Class	
GO:0061504	biolink:NamedThing	cyclic threonylcarbamoyladenosine biosynthetic process	The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.	got7fsn_ti							dph	2013-01-22T14:25:00Z						biological_process											owl:Class	
GO:0046554	biolink:NamedThing	malate dehydrogenase (NADP+) activity	Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+.	got7fsn_ti	NADP-malate dehydrogenase activity|malic dehydrogenase (nicotinamide adenine dinucleotide phosphate)|(S)-malate:NADP+ oxidoreductase activity|NADP malate dehydrogenase activity|NADP-linked malate dehydrogenase activity|malate NADP dehydrogenase activity											RHEA:10824|KEGG_REACTION:R00343|EC:1.1.1.82|MetaCyc:MALATE-DEHYDROGENASE-NADP+-RXN		molecular_function											owl:Class	
GO:0046844	biolink:NamedThing	chorion micropyle formation	Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization.	got7fsn_ti														biological_process											owl:Class	
GO:0062183	biolink:NamedThing	all-trans retinoic acid 18-hydroxylase activity	Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							dph	2019-11-26T18:41:32Z				RHEA:55856		molecular_function											owl:Class	
GO:1990896	biolink:NamedThing	protein localization to cell cortex of cell tip	A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip.	got7fsn_ti							vw	2015-11-05T08:41:49Z						biological_process											owl:Class	
GO:0033619	biolink:NamedThing	membrane protein proteolysis	The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.	got7fsn_ti														biological_process											owl:Class	
GO:0033334	biolink:NamedThing	fin morphogenesis	The process in which the anatomical structures of a fin are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0003934	biolink:NamedThing	GTP cyclohydrolase I activity	Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.	got7fsn_ti	guanosine triphosphate 8-deformylase activity|dihydroneopterin triphosphate synthase activity|GTP 8-formylhydrolase activity|guanosine triphosphate cyclohydrolase activity|GTP 7,8-8,9-dihydrolase activity											EC:3.5.4.16|MetaCyc:GTP-CYCLOHYDRO-I-RXN|Reactome:R-HSA-1474146|RHEA:17473|KEGG_REACTION:R00424		molecular_function											owl:Class	
GO:0045238	biolink:NamedThing	CXCR2 chemokine receptor binding	Binding to a CXCR2 chemokine receptor.	got7fsn_ti	CXCR2 chemokine receptor ligand													molecular_function											owl:Class	
GO:0005153	biolink:NamedThing	interleukin-8 receptor binding	Binding to an interleukin-8 receptor.	got7fsn_ti	IL-8|interleukin-8 receptor ligand													molecular_function											owl:Class	
GO:0061045	biolink:NamedThing	negative regulation of wound healing	Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.	got7fsn_ti							dph	2010-02-25T10:33:30Z						biological_process											owl:Class	
GO:0047733	biolink:NamedThing	CDP-glucose 4,6-dehydratase activity	Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O.	got7fsn_ti	cytidine diphosphoglucose oxidoreductase activity|CDPglucose 4,6-hydro-lyase activity|CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)|CDPglucose 4,6-dehydratase activity|CDP-glucose 4,6-hydro-lyase activity											EC:4.2.1.45|MetaCyc:CDP-GLUCOSE-46-DEHYDRATASE-RXN|RHEA:17153|KEGG_REACTION:R02426		molecular_function											owl:Class	
GO:0046859	biolink:NamedThing	hydrogenosomal membrane	The lipid bilayer surrounding a hydrogenosome.	got7fsn_ti	hydrogenosome membrane													cellular_component											owl:Class	
GO:1990166	biolink:NamedThing	protein localization to site of double-strand break	Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred.	got7fsn_ti	protein localization to site of DSB|protein localisation to site of double-strand break|protein localization to double-strand break site						mah	2013-08-08T11:27:00Z						biological_process											owl:Class	
GO:0047974	biolink:NamedThing	guanosine deaminase activity	Catalysis of the reaction: guanosine + H2O = xanthosine + NH3.	got7fsn_ti	guanosine aminohydrolase activity|guanosine aminase activity											MetaCyc:GUANOSINE-DEAMINASE-RXN|RHEA:12861|EC:3.5.4.15		molecular_function											owl:Class	
GO:0103012	biolink:NamedThing	ferredoxin-thioredoxin reductase activity	Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide.	got7fsn_ti	ferredoxin:thioredoxin reductase activity	https://github.com/geneontology/go-ontology/issues/18939									GO:0030385	EC:1.8.7.2|MetaCyc:RXN-9944|RHEA:42336		molecular_function											owl:Class	
GO:0033716	biolink:NamedThing	nucleoside oxidase (hydrogen peroxide-forming) activity	Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide.	got7fsn_ti	nucleoside:oxygen 5'-oxidoreductase (hydrogen peroxide-forming) activity				Two other reactions might be associated with this activity: (1a) adenosine + O2 = 5'-dehydroadenosine + hydrogen peroxide, and (1b) 5'-dehydroadenosine + O2 = 9-riburonosyladenine + hydrogen peroxide.							MetaCyc:1.1.3.39-RXN|EC:1.1.3.39|RHEA:15489		molecular_function											owl:Class	
GO:0005152	biolink:NamedThing	interleukin-1 receptor antagonist activity	Blocks the binding of interleukin-1 to the interleukin-1 receptor complex.	got7fsn_ti	IL-1ra													molecular_function											owl:Class	
GO:0048847	biolink:NamedThing	adenohypophysis formation	The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.	got7fsn_ti	anterior pituitary gland formation|anterior pituitary biosynthesis|anterior pituitary gland biosynthesis|anterior pituitary formation|adenophysis formation|adenophysis biosynthesis													biological_process											owl:Class	
GO:0030193	biolink:NamedThing	regulation of blood coagulation	Any process that modulates the frequency, rate or extent of blood coagulation.	got7fsn_ti														biological_process											owl:Class	
GO:0061041	biolink:NamedThing	regulation of wound healing	Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.	got7fsn_ti							dph	2010-02-25T10:14:37Z						biological_process											owl:Class	
GO:1990144	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to hypoxia	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered.	got7fsn_ti							pr	2013-07-23T10:18:10Z						biological_process											owl:Class	
GO:0102128	biolink:NamedThing	chalcone synthase activity	Catalysis of the reaction: 4-dihydrocoumaroyl-CoA + 3 malonyl-CoA + 3 H+ = phloretin + 4 coenzyme A + 3 carbon dioxide.	got7fsn_ti												MetaCyc:RXN-11468|EC:2.3.1.74		molecular_function											owl:Class	
GO:0030233	biolink:NamedThing	deoxynucleotide transmembrane transporter activity	Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.	got7fsn_ti														molecular_function											owl:Class	
GO:0015215	biolink:NamedThing	nucleotide transmembrane transporter activity	Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0031287	biolink:NamedThing	positive regulation of sorocarp stalk cell differentiation	Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	positive regulation of stalk cell differentiation|upregulation of stalk cell differentiation|up-regulation of stalk cell differentiation|stimulation of stalk cell differentiation|activation of stalk cell differentiation|up regulation of stalk cell differentiation													biological_process											owl:Class	
GO:0032109	biolink:NamedThing	positive regulation of response to nutrient levels	Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.	got7fsn_ti	stimulation of response to nutrient levels|up-regulation of response to nutrient levels|activation of response to nutrient levels|upregulation of response to nutrient levels|up regulation of response to nutrient levels													biological_process											owl:Class	
GO:0034791	biolink:NamedThing	isobutylamine N-hydroxylase activity	Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O.	got7fsn_ti												EC:1.14.13.-|UM-BBD_reactionID:r1053		molecular_function											owl:Class	
GO:0006975	biolink:NamedThing	DNA damage induced protein phosphorylation	The widespread phosphorylation of various molecules, triggering many downstream processes, that occurs in response to the detection of DNA damage.	got7fsn_ti														biological_process											owl:Class	
GO:0102279	biolink:NamedThing	lecithin:11-cis retinol acyltransferase activity	Catalysis of the reaction: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine <=> a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine.	got7fsn_ti												EC:2.3.1.135|MetaCyc:RXN-12563		molecular_function											owl:Class	
GO:2001002	biolink:NamedThing	positive regulation of xylan catabolic process	Any process that activates or increases the frequency, rate or extent of xylan catabolic process.	got7fsn_ti	positive regulation of xylan catabolism|positive regulation of xylan degradation|positive regulation of xylan breakdown						tt	2011-08-08T03:23:22Z						biological_process											owl:Class	
GO:2000926	biolink:NamedThing	positive regulation of cellodextrin metabolic process	Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process.	got7fsn_ti	positive regulation of cellodextrin metabolism						tt	2011-08-01T12:39:59Z						biological_process											owl:Class	
GO:0102710	biolink:NamedThing	D-inositol-3-phosphate glycosyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-inositol 3-phosphate = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H+.	got7fsn_ti												EC:2.4.1.250|MetaCyc:RXN-6501|RHEA:26188		molecular_function											owl:Class	
GO:0097411	biolink:NamedThing	hypoxia-inducible factor-1alpha signaling pathway	A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia.	got7fsn_ti	HIF1alpha pathway|hypoxia-inducible factor signaling|hypoxia-inducible factor-1alpha signalling pathway						pr	2012-11-06T10:46:33Z						biological_process											owl:Class	
GO:2000856	biolink:NamedThing	negative regulation of mineralocorticoid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion.	got7fsn_ti							bf	2011-07-26T08:46:42Z						biological_process											owl:Class	
GO:0018513	biolink:NamedThing	dibenzothiophene dihydrodiol dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH.	got7fsn_ti	cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase activity											UM-BBD_reactionID:r0161|EC:1.3.1.60|KEGG_REACTION:R05310|RHEA:24188|MetaCyc:1.3.1.60-RXN		molecular_function											owl:Class	
GO:0090695	biolink:NamedThing	Wpl/Pds5 cohesin loading/unloading complex	A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA.	got7fsn_ti							tb	2016-08-24T17:09:11Z						cellular_component											owl:Class	
GO:0031501	biolink:NamedThing	mannosyltransferase complex	A complex that posseses mannosyltransferase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0001703	biolink:NamedThing	gastrulation with mouth forming first	A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.	got7fsn_ti	protostomic gastrulation													biological_process											owl:Class	
GO:0005118	biolink:NamedThing	sevenless binding	Binding to a sevenless (sev) protein, a receptor tyrosine kinase.	got7fsn_ti	sev ligand|sevenless ligand|sev binding													molecular_function											owl:Class	
GO:0002482	biolink:NamedThing	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	got7fsn_ti	exogenous peptide antigen processing and presentation via MHC class Ib, TAP-independent|TAP-independent exogenous peptide antigen processing and presentation via MHC class Ib|TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class Ib													biological_process											owl:Class	
GO:0004423	biolink:NamedThing	iduronate-2-sulfatase activity	Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.	got7fsn_ti	iduronide-2-sulfate sulfatase activity|iduronate-2-sulfate sulfatase activity|iduronate-2-sulphatase activity|chondroitinsulfatase|L-iduronate 2-sulfate sulfatase activity|iduronate sulfatase activity|sulfoiduronate sulfohydrolase activity|L-idurono sulfate sulfatase activity|2-sulfo-L-iduronate 2-sulfatase activity|sulfo-L-iduronate sulfatase activity|iduronate sulfate sulfatase activity|idurono-2-sulfatase activity|L-iduronate-2-sulfate 2-sulfohydrolase activity|L-iduronosulfatase activity											MetaCyc:3.1.6.13-RXN|EC:3.1.6.13|Reactome:R-HSA-9036046|Reactome:R-HSA-1793182|Reactome:R-HSA-1678650|Reactome:R-HSA-2262743		molecular_function											owl:Class	
GO:0014065	biolink:NamedThing	phosphatidylinositol 3-kinase signaling	A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.	got7fsn_ti	PI 3-kinase cascade|PI3K signaling|PI3K cascade|phosphatidylinositol 3-kinase signal transduction|phosphatidylinositol 3-kinase cascade|phosphoinositide 3-kinase cascade|PI3K signal transduction													biological_process											owl:Class	
GO:0048015	biolink:NamedThing	phosphatidylinositol-mediated signaling	A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.	got7fsn_ti	inositol phospholipid-mediated signaling|phosphatidylinositol-mediated signal transduction|phosphoinositide-mediated signalling|phosphatidylinositol-mediated signalling|phosphoinositide-mediated signaling													biological_process											owl:Class	
GO:0008760	biolink:NamedThing	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity	Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine.	got7fsn_ti	phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase activity|enoylpyruvate transferase activity|pyruvate-uridine diphospho-N-acetylglucosamine transferase activity|pyruvic-uridine diphospho-N-acetylglucosaminyltransferase activity|phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase activity|UDP-N-acetylglucosamine enoylpyruvyltransferase activity|pyruvate-uridine diphospho-N-acetyl-glucosamine transferase activity|MurA transferase activity|UDP-N-acetylglucosamine 1-carboxyvinyl-transferase activity|phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase activity|phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase activity|phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase activity|phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase activity|pyruvate-UDP-acetylglucosamine transferase activity											RHEA:18681|EC:2.5.1.7|MetaCyc:UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN|KEGG_REACTION:R00660		molecular_function											owl:Class	
GO:0004378	biolink:NamedThing	GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity	Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.	got7fsn_ti	glycolipid 3-alpha-mannosyltransferase activity|guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity|GDP-mannose-oligosaccharide-lipid mannosyltransferase II|GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity|mannosyltransferase II activity|GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity											RHEA:29515|EC:2.4.1.132|MetaCyc:2.4.1.132-RXN		molecular_function											owl:Class	
GO:0047873	biolink:NamedThing	dolichyl-phosphatase activity	Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate.	got7fsn_ti	dolichyl-phosphate phosphohydrolase activity|dolichol phosphate phosphatase activity|dolichyl pyrophosphate phosphatase activity|Dol-P-P phosphohydrolase activity|dolichyl monophosphate phosphatase activity|dolichol phosphatase activity|dolichol monophosphatase activity|polyprenylphosphate phosphatase activity|dolichyl phosphate phosphatase activity|Dol-P phosphatase activity|polyisoprenyl phosphate phosphatase activity											MetaCyc:DOLICHYL-PHOSPHATASE-RXN|EC:3.1.3.51|RHEA:13797		molecular_function											owl:Class	
GO:0060417	biolink:NamedThing	yolk	The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.	got7fsn_ti														cellular_component											owl:Class	
GO:0033461	biolink:NamedThing	GGU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GGU codon.	got7fsn_ti	glycine tRNA|GGT codon-amino acid adaptor activity				Note that in the standard genetic code, GGT codes for glycine.									molecular_function											owl:Class	
GO:0004535	biolink:NamedThing	poly(A)-specific ribonuclease activity	Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.	got7fsn_ti	2',3'-exoribonuclease activity|3'-exoribonuclease activity|poly(A)-specific RNase activity											Reactome:R-HSA-429992|EC:3.1.13.4|Reactome:R-HSA-429955|MetaCyc:3.1.13.4-RXN|Reactome:R-HSA-430021		molecular_function											owl:Class	
GO:0070855	biolink:NamedThing	myosin VI head/neck binding	Binding to the head/neck region of a myosin VI heavy chain.	got7fsn_ti							mah	2009-08-13T01:45:08Z						molecular_function											owl:Class	
GO:0102037	biolink:NamedThing	4-nitrotoluene monooxygenase activity	Catalysis of the reaction: H+ + 4-nitrotoluene + NADH + O2 <=> 4-nitrobenzyl alcohol + NAD+ + H2O.	got7fsn_ti												MetaCyc:R361-RXN		molecular_function											owl:Class	
GO:0003220	biolink:NamedThing	left ventricular cardiac muscle tissue morphogenesis	The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.	got7fsn_ti	left ventricular myocardium morphogenesis						dph	2009-10-13T10:18:05Z						biological_process											owl:Class	
GO:0050013	biolink:NamedThing	2-dehydropantoate aldolase activity	Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde.	got7fsn_ti	2-dehydropantoate formaldehyde-lyase activity|ketopantoaldolase activity|2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming)											RHEA:23276|EC:4.1.2.12|MetaCyc:KETOPANTOALDOLASE-RXN		molecular_function											owl:Class	
GO:0038047	biolink:NamedThing	morphine receptor activity	Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein.	got7fsn_ti	mu-opioid receptor activity						bf	2011-11-14T01:35:18Z						molecular_function											owl:Class	
GO:0070113	biolink:NamedThing	organellar chromatophore inner membrane	The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore.	got7fsn_ti	Paulinella-type chromatophore inner membrane													cellular_component											owl:Class	
GO:0070112	biolink:NamedThing	organellar chromatophore membrane	Either of the lipid bilayers that surround an organellar chromatophore.	got7fsn_ti	Paulinella-type chromatophore membrane													cellular_component											owl:Class	
GO:0021717	biolink:NamedThing	inferior olivary nucleus maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	got7fsn_ti	inferior olive maturation													biological_process											owl:Class	
GO:0106144	biolink:NamedThing	fraxetin 5-hydroxylase activity	Catalyzes the reaction fraxetin+ NAD(P)H + 02= sideretin + NAD(P)(+) + H20.	got7fsn_ti							hjd	2018-09-07T18:24:41Z				RHEA:57844|EC:1.14.14.164		molecular_function											owl:Class	
GO:0036427	biolink:NamedThing	all-trans-undecaprenyl-phosphate mannosyltransferase activity	Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP.	got7fsn_ti							bf	2013-09-16T13:23:06Z				RHEA:28118		molecular_function											owl:Class	
GO:0047267	biolink:NamedThing	undecaprenyl-phosphate mannosyltransferase activity	Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol.	got7fsn_ti	GDP mannose-undecaprenyl phosphate mannosyltransferase activity|GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase activity|GDP-D-mannose:lipid phosphate transmannosylase activity|guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity											EC:2.4.1.54		molecular_function											owl:Class	
GO:0047950	biolink:NamedThing	glutathione oxidase activity	Catalysis of the reaction: 2 glutathione + O(2) = glutathione disulfide + H(2)O(2).	got7fsn_ti	glutathione:oxygen oxidoreductase activity											EC:1.8.3.3|KEGG_REACTION:R00120|MetaCyc:GLUTATHIONE-OXIDASE-RXN|RHEA:24112		molecular_function											owl:Class	
GO:0090433	biolink:NamedThing	palmitoyl-CoA ligase activity	Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.	got7fsn_ti	palmitoyl-CoA synthetase activity						tb	2012-07-25T03:31:31Z				Reactome:R-HSA-434382		molecular_function											owl:Class	
GO:0043886	biolink:NamedThing	structural constituent of carboxysome	The action of a molecule that contributes to the structural integrity of a carboxysome, an organelle found in all cyanobacteria and some chemoautotrophs, consisting of a proteinaceous coat and enzymes for the fixation of CO(2).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19743												molecular_function											owl:Class	
GO:0010618	biolink:NamedThing	aerenchyma formation	The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti														biological_process											owl:Class	
GO:0016235	biolink:NamedThing	aggresome	An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.	got7fsn_ti												Wikipedia:Aggresome		cellular_component											owl:Class	
GO:0042660	biolink:NamedThing	positive regulation of cell fate specification	Any process that activates or enables a cell to adopt a specific fate.	got7fsn_ti	up regulation of cell fate specification|activation of cell fate specification|upregulation of cell fate specification|stimulation of cell fate specification|up-regulation of cell fate specification													biological_process											owl:Class	
GO:0044100	biolink:NamedThing	sporoplasm	The complex infective apparatus corresponding to the central mass of cytoplasm within a spore that is injected into a host cell by various parasitic microorganisms.	got7fsn_ti							jl	2009-06-09T03:27:03Z						cellular_component											owl:Class	
GO:0052885	biolink:NamedThing	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Catalysis of the reaction: H(2)O + all-trans-retinyl ester = 11-cis-retinol + fatty acid.	got7fsn_ti	all-trans-retinol isomerase:hydrolase activity|all-trans-retinyl ester acylhydrolase, 11-cis retinol forming activity|retinoid isomerohydrolase activity|all-trans-retinylester 11-cis isomerohydrolase activity|retinol isomerase activity											EC:3.1.1.64|RHEA:31771|MetaCyc:RXN-12550|KEGG_REACTION:R08388		molecular_function											owl:Class	
GO:1990877	biolink:NamedThing	Lst4-Lst7 complex	A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains Follicular (FLCN) and either follicular interaction protein 1 (FNIP1) or FNIP2.	got7fsn_ti	FNIP-Folliculin RagC/D GAP complex|FLCN-FNIP1 complex|FLCN-FNIP2 complex						rb	2015-10-01T22:44:58Z						cellular_component											owl:Class	
GO:0047709	biolink:NamedThing	bis(2-ethylhexyl)phthalate esterase activity	Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H(2)O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+).	got7fsn_ti	DEHP esterase activity|bis(2-ethylhexyl)phthalate acylhydrolase activity											KEGG_REACTION:R04202|MetaCyc:BIS2-ETHYLHEXYLPHTHALATE-ESTERASE-RXN|EC:3.1.1.60|RHEA:15529		molecular_function											owl:Class	
GO:0032499	biolink:NamedThing	detection of peptidoglycan	The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.	got7fsn_ti														biological_process											owl:Class	
GO:0032494	biolink:NamedThing	response to peptidoglycan	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.	got7fsn_ti														biological_process											owl:Class	
GO:0004458	biolink:NamedThing	D-lactate dehydrogenase (cytochrome) activity	Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate.	got7fsn_ti	cytochrome-dependent D-(-)-lactate dehydrogenase activity|D-(-)-lactic cytochrome c reductase activity|lactic acid dehydrogenase activity|D-lactate ferricytochrome c oxidoreductase activity|D-lactate-cytochrome c reductase activity|(R)-lactate:ferricytochrome-c 2-oxidoreductase activity|D-lactate (cytochrome) dehydrogenase activity											RHEA:13521|MetaCyc:D-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN|EC:1.1.2.4		molecular_function											owl:Class	
GO:0102216	biolink:NamedThing	maltodextrin water dikinase	Catalysis of the reaction: ATP + H2O + a maltodextrin = AMP + hydrogenphosphate + a 6-phosphogluco-maltodextrin.	got7fsn_ti												MetaCyc:RXN-12201|EC:2.7.9.4		molecular_function											owl:Class	
GO:0060716	biolink:NamedThing	labyrinthine layer blood vessel development	The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.	got7fsn_ti							dph	2009-06-11T09:04:38Z						biological_process											owl:Class	
GO:0006517	biolink:NamedThing	protein deglycosylation	The removal of sugar residues from a glycosylated protein.	got7fsn_ti	glycoprotein deglycosylation													biological_process											owl:Class	
GO:0061990	biolink:NamedThing	beta-ketodecanoyl-[acyl-carrier-protein] synthase activity	Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2.	got7fsn_ti							dph	2018-02-15T22:29:03Z				RHEA:42264|MetaCyc:RXN-13613		molecular_function											owl:Class	
GO:0042709	biolink:NamedThing	succinate-CoA ligase complex	A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP.	got7fsn_ti														cellular_component											owl:Class	
GO:0033660	biolink:NamedThing	suppression by symbiont of host resistance gene-dependent defense response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	down-regulation by symbiont of host gene-for-gene resistance|suppression by symbiont of host resistance gene-dependent defense response|downregulation by symbiont of pathogen-race/host plant cultivar-specific resistance in symbiont|down regulation by symbiont of defense response in host by specific elicitors|inhibition by symbiont of host resistance gene-dependent defense response|negative regulation by symbiont of host resistance gene-dependent defense response													biological_process											owl:Class	
GO:0070889	biolink:NamedThing	platelet alpha granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets.	got7fsn_ti	platelet alpha granule organization and biogenesis|platelet alpha granule organisation|platelet alpha-granule organization						mah	2009-08-28T10:43:31Z						biological_process											owl:Class	
GO:0031593	biolink:NamedThing	polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination of the target protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0039689	biolink:NamedThing	negative stranded viral RNA replication	A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA).	got7fsn_ti	(-)ss viral RNA replication						bf	2013-10-17T15:40:27Z				VZ:1096		biological_process											owl:Class	
GO:0039694	biolink:NamedThing	viral RNA genome replication	The replication of a viral RNA genome.	got7fsn_ti							bf	2013-10-23T15:24:36Z						biological_process											owl:Class	
GO:0050078	biolink:NamedThing	malonate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA.	got7fsn_ti	acetyl-CoA:malonate CoA-transferase activity|malonate coenzyme A-transferase activity											KEGG_REACTION:R00743|RHEA:18817|MetaCyc:MALONATE-COA-TRANSFERASE-RXN|EC:2.8.3.3		molecular_function											owl:Class	
GO:0047163	biolink:NamedThing	3,4-dichloroaniline N-malonyltransferase activity	Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA.	got7fsn_ti	malonyl-CoA:3,4-dichloroaniline N-malonyltransferase activity											EC:2.3.1.114|RHEA:21060|MetaCyc:2.3.1.114-RXN|KEGG_REACTION:R04050		molecular_function											owl:Class	
GO:0018177	biolink:NamedThing	protein uridylylation	The addition of phospho-uridine to a protein amino acid.	got7fsn_ti	protein amino acid uridylylation													biological_process											owl:Class	
GO:0009327	biolink:NamedThing	NAD(P)+ transhydrogenase complex (AB-specific)	A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified.	got7fsn_ti														cellular_component											owl:Class	
GO:0002188	biolink:NamedThing	translation reinitiation	A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon.	got7fsn_ti							hjd	2011-06-22T12:31:13Z						biological_process											owl:Class	
GO:0071951	biolink:NamedThing	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet).	got7fsn_ti							mah	2010-10-08T11:54:38Z						biological_process											owl:Class	
GO:0102675	biolink:NamedThing	C4-methyltransferase activity	Catalysis of the reaction: 24-ethylidenelophenol + a demethylated methyl acceptor <=> avenasterol + a methylated methyl acceptor.	got7fsn_ti												MetaCyc:RXN-4208		molecular_function											owl:Class	
GO:1902489	biolink:NamedThing	hepatoblast apoptotic process	Any apoptotic process in a hepatoblast.	got7fsn_ti	hepatoblast apoptosis						cls	2013-11-12T17:02:52Z						biological_process											owl:Class	
GO:0043739	biolink:NamedThing	G/U mismatch-specific uracil-DNA glycosylase activity	Catalysis of the removal of uracil from a U*G mispair by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free uracil and leaves an apyrimidinic (AP) site.	got7fsn_ti	uracil mismatch repair protein|MUG|GU mismatch-specific uracil-DNA glycosylase activity													molecular_function											owl:Class	
GO:0015574	biolink:NamedThing	trehalose transmembrane transporter activity	Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens.	got7fsn_ti	trehalose permease activity										GO:0015584			molecular_function											owl:Class	
GO:0051542	biolink:NamedThing	elastin biosynthetic process	The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.	got7fsn_ti														biological_process											owl:Class	
GO:0051541	biolink:NamedThing	elastin metabolic process	The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.	got7fsn_ti	elastin metabolism													biological_process											owl:Class	
GO:0044733	biolink:NamedThing	envenomation resulting in modulation of acid-sensing ion channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.	got7fsn_ti	envenomation resulting in modulation of ASIC channel activity in other organism						jl	2012-11-06T15:58:36Z						biological_process											owl:Class	
GO:0090572	biolink:NamedThing	RNA polymerase III transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter.	got7fsn_ti							tb	2014-05-09T13:26:16Z						cellular_component											owl:Class	
GO:0000309	biolink:NamedThing	nicotinamide-nucleotide adenylyltransferase activity	Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+.	got7fsn_ti	adenosine triphosphate-nicotinamide mononucleotide transadenylase activity|NAD+ pyrophosphorylase activity|diphosphopyridine nucleotide pyrophosphorylase activity|NAD(+) pyrophosphorylase activity|NMNAT activity|ATP:nicotinamide-nucleotide adenylyltransferase activity|nicotinamide adenine dinucleotide pyrophosphorylase activity|nicotinamide mononucleotide adenylyltransferase activity|NMN adenylyltransferase activity|NAD(+) diphosphorylase activity|ATP:NMN adenylyltransferase activity|NAD+ diphosphorylase activity											Reactome:R-HSA-8939959|RHEA:21360|MetaCyc:2.7.7.1-RXN|EC:2.7.7.1		molecular_function											owl:Class	
GO:0050586	biolink:NamedThing	3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity	Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H(+) + O(2) = N-acetylanthranilate + CO.	got7fsn_ti	(1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity|3-hydroxy-2-methyl-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)|1H-3-hydroxy-4-oxo quinaldine 2,4-dioxygenase activity|3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase activity|1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity											MetaCyc:1.13.11.48-RXN|RHEA:21572|KEGG_REACTION:R05720|EC:1.13.11.48		molecular_function											owl:Class	
GO:0051145	biolink:NamedThing	smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.	got7fsn_ti	nonstriated muscle cell differentiation													biological_process											owl:Class	
GO:1990079	biolink:NamedThing	cartilage homeostasis	A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function.	got7fsn_ti	regulation of cartilage homeostasis|positive regulation of cartilage homeostasis|negative regulation of cartilage homeostasis						hjd	2013-04-29T20:10:15Z			GO:1902095|GO:1902096|GO:1902094			biological_process											owl:Class	
GO:0044095	biolink:NamedThing	host cell nucleoplasm	That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							jl	2009-04-22T02:02:51Z						cellular_component											owl:Class	
GO:0061986	biolink:NamedThing	negative regulation of transcription by glucose	Any process involving glucose that decreases the frequency, rate or extent or transcription.	got7fsn_ti							dph	2018-02-15T17:39:14Z						biological_process											owl:Class	
GO:0071055	biolink:NamedThing	alpha9-beta1 integrin-ADAM9 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.	got7fsn_ti	ITGA9-ITGB1-ADAM9 complex						mah	2009-11-03T03:59:24Z						cellular_component											owl:Class	
GO:0033006	biolink:NamedThing	regulation of mast cell activation involved in immune response	Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response.	got7fsn_ti	regulation of mast cell activation during immune response													biological_process											owl:Class	
GO:0042984	biolink:NamedThing	regulation of amyloid precursor protein biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.	got7fsn_ti	regulation of amyloid precursor protein anabolism|regulation of amyloid precursor protein synthesis|regulation of amyloid precursor protein biosynthesis|regulation of APP biosynthesis|regulation of APP biosynthetic process|regulation of amyloid precursor protein formation													biological_process											owl:Class	
GO:0010559	biolink:NamedThing	regulation of glycoprotein biosynthetic process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	got7fsn_ti														biological_process											owl:Class	
GO:0030749	biolink:NamedThing	loganate O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin.	got7fsn_ti	S-adenosyl-L-methionine:loganic acid methyltransferase activity|S-adenosyl-L-methionine:loganate 11-O-methyltransferase activity|loganate methyltransferase activity											RHEA:12508|MetaCyc:LOGANATE-O-METHYLTRANSFERASE-RXN|EC:2.1.1.50		molecular_function											owl:Class	
GO:0034461	biolink:NamedThing	uropod retraction	The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell.	got7fsn_ti														biological_process											owl:Class	
GO:0032796	biolink:NamedThing	uropod organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated.	got7fsn_ti	uropod organisation|uropod organization and biogenesis													biological_process											owl:Class	
GO:0106298	biolink:NamedThing	13-series resolvin biosynthetic process	The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid.	got7fsn_ti							hjd	2020-08-25T13:50:53Z						biological_process											owl:Class	
GO:0047148	biolink:NamedThing	methylamine-glutamate N-methyltransferase activity	Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH(4)(+).	got7fsn_ti	methylamine-glutamate methyltransferase activity|N-methylglutamate synthase activity|methylamine:L-glutamate N-methyltransferase activity											RHEA:15837|KEGG_REACTION:R01586|EC:2.1.1.21|MetaCyc:2.1.1.21-RXN		molecular_function											owl:Class	
GO:0050304	biolink:NamedThing	nitrous-oxide reductase activity	Catalysis of the reaction: H(2)O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide.	got7fsn_ti	nitrogen:acceptor oxidoreductase (N2O-forming)|nitrous oxide reductase activity|N2O reductase activity|nitrogen:(acceptor) oxidoreductase (N2O-forming)											EC:1.7.2.4|KEGG_REACTION:R02804|RHEA:43108|MetaCyc:RXN-12130		molecular_function											owl:Class	
GO:0016662	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome.	got7fsn_ti												EC:1.7.2.-		molecular_function											owl:Class	
GO:0003839	biolink:NamedThing	gamma-glutamylcyclotransferase activity	Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.	got7fsn_ti	gamma-glutamyl-amino acid cyclotransferase activity|(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)|L-glutamic cyclase activity|gamma-L-glutamylcyclotransferase activity											EC:4.3.2.9|Reactome:R-HSA-6785928|RHEA:20505|MetaCyc:GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN|Reactome:R-HSA-1247922		molecular_function											owl:Class	
GO:0140024	biolink:NamedThing	plus-end-directed endosome transport along mitotic spindle midzone microtubule	The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination.	got7fsn_ti							pg	2017-04-29T11:34:23Z						biological_process											owl:Class	
GO:1990256	biolink:NamedThing	signal clustering	Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response.	got7fsn_ti	ligand clustering						tb	2013-12-18T01:13:59Z						biological_process											owl:Class	
GO:0099618	biolink:NamedThing	UDP-glucuronic acid dehydrogenase activity	Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+.	got7fsn_ti	UDP-GlcUA decarboxylase activity											RHEA:24702|EC:1.1.1.305		molecular_function											owl:Class	
GO:1903038	biolink:NamedThing	negative regulation of leukocyte cell-cell adhesion	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.	got7fsn_ti	down regulation of leukocyte cell-cell adhesion|inhibition of leukocyte cell-cell adhesion|down-regulation of leukocyte cell adhesion|down-regulation of leukocyte cell-cell adhesion|downregulation of leukocyte cell adhesion|inhibition of leukocyte adhesion|down regulation of leukocyte cell adhesion|negative regulation of leukocyte cell adhesion|negative regulation of leukocyte adhesion|downregulation of leukocyte adhesion|down regulation of leukocyte adhesion|down-regulation of leukocyte adhesion|downregulation of leukocyte cell-cell adhesion|inhibition of leukocyte cell adhesion				Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion		rl	2014-05-19T15:30:05Z						biological_process											owl:Class	
GO:0052089	biolink:NamedThing	modulation by symbiont of host salicylic acid-mediated defense response	Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of host SA-mediated defense response|modulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction										GO:0052284			biological_process											owl:Class	
GO:2000031	biolink:NamedThing	regulation of salicylic acid mediated signaling pathway	Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway.	got7fsn_ti	regulation of salicylic acid mediated signalling pathway						tb	2010-08-05T11:32:24Z						biological_process											owl:Class	
GO:0044555	biolink:NamedThing	negative regulation of heart rate in other organism	Any process that stops, prevents or reduces the frequency of heart contraction of another organism.	got7fsn_ti							jl	2012-03-29T03:01:20Z						biological_process											owl:Class	
GO:0042075	biolink:NamedThing	nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide	The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.	got7fsn_ti	nickel incorporation into nickel-iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide											RESID:AA0310		biological_process											owl:Class	
GO:0010303	biolink:NamedThing	limit dextrinase activity	Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan.	got7fsn_ti	R-enzyme|dextrin alpha-1,6-glucanohydrolase activity|amylopectin-1,6-glucosidase activity											MetaCyc:3.2.1.142-RXN|MetaCyc:RXN-1824|MetaCyc:3.2.1.10-RXN|EC:3.2.1.142		molecular_function											owl:Class	
GO:0031832	biolink:NamedThing	type 6 serotonin receptor binding	Binding to a type 6 serotonin receptor.	got7fsn_ti	5-hydroxytryptamine 6 receptor binding|type 6 serotonin receptor ligand													molecular_function											owl:Class	
GO:0034906	biolink:NamedThing	N-isopropylaniline 1,2-dixoxygenase activity	Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine.	got7fsn_ti												UM-BBD_reactionID:r0721|EC:1.14.12.-		molecular_function											owl:Class	
GO:0098671	biolink:NamedThing	adhesion receptor-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located.	got7fsn_ti	viral attachment to host adhesion receptor						dos	2017-01-16T13:22:54Z				VZ:3943		biological_process											owl:Class	
GO:0102784	biolink:NamedThing	lutein oxygenase activity	Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.	got7fsn_ti												MetaCyc:RXN-7884		molecular_function											owl:Class	
GO:0048564	biolink:NamedThing	photosystem I assembly	The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane.	got7fsn_ti											GO:0010251			biological_process											owl:Class	
GO:0097477	biolink:NamedThing	lateral motor column neuron migration	The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme.	got7fsn_ti							pr	2013-04-23T13:05:32Z						biological_process											owl:Class	
GO:0097476	biolink:NamedThing	spinal cord motor neuron migration	The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.	got7fsn_ti							pr	2013-04-23T13:03:46Z						biological_process											owl:Class	
GO:0018815	biolink:NamedThing	3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity	Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine.	got7fsn_ti												UM-BBD_reactionID:r0051|MetaCyc:RXN-645		molecular_function											owl:Class	
GO:0022878	biolink:NamedThing	protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	sucrose PTS transporter activity											RHEA:49236|MetaCyc:SUCROSEPHOSPHO-RXN		molecular_function											owl:Class	
GO:0090179	biolink:NamedThing	planar cell polarity pathway involved in neural tube closure	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.	got7fsn_ti							tb	2009-12-14T11:20:27Z						biological_process											owl:Class	
GO:0090178	biolink:NamedThing	regulation of establishment of planar polarity involved in neural tube closure	Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.	got7fsn_ti							tb	2009-12-14T11:14:27Z						biological_process											owl:Class	
GO:0047868	biolink:NamedThing	dimethylmaleate hydratase activity	Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O.	got7fsn_ti	(2R,3S)-2,3-dimethylmalate hydro-lyase activity|(2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming)											MetaCyc:DIMETHYLMALEATE-HYDRATASE-RXN|KEGG_REACTION:R03069|EC:4.2.1.85|RHEA:20253		molecular_function											owl:Class	
GO:0060384	biolink:NamedThing	innervation	The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0036070	biolink:NamedThing	light-independent bacteriochlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.	got7fsn_ti	light independent bacteriochlorophyll biosynthetic process|light-independent bacteriochlorophyll synthesis|light-independent bacteriochlorophyll biosynthesis|light-independent bacteriochlorophyll formation|light-independent bacteriochlorophyll anabolism						bf	2011-12-15T04:46:25Z						biological_process											owl:Class	
GO:0110012	biolink:NamedThing	protein localization to P-body	Any process in which a protein is transported to, or maintained at, a P-body.	got7fsn_ti	protein localization to P body|protein localization to cytoplasmic mRNA processing body|protein localisation to P-body						kmv	2017-05-03T14:04:51Z						biological_process											owl:Class	
GO:0050004	biolink:NamedThing	isoflavone 7-O-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside.	got7fsn_ti	uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase activity|UDPglucose-flavonoid 7-O-glucosyltransferase activity|UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose:isoflavone 7-O-glucosyltransferase activity|UDPglucose:isoflavone 7-O-beta-D-glucosyltransferase activity											MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.170|RHEA:56344		molecular_function											owl:Class	
GO:0033963	biolink:NamedThing	cholesterol-5,6-oxide hydrolase activity	Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol.	got7fsn_ti	cholesterol-epoxide hydrolase activity|5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase activity|ChEH											EC:3.3.2.11|MetaCyc:RXN-8651|MetaCyc:RXN-8650		molecular_function											owl:Class	
GO:0034027	biolink:NamedThing	(carboxyethyl)arginine beta-lactam-synthase activity	Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+).	got7fsn_ti	beta-lactam synthetase activity|L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity|L-2-N-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity											RHEA:23620|EC:6.3.3.4|MetaCyc:6.3.3.4-RXN|KEGG_REACTION:R05467		molecular_function											owl:Class	
GO:0016882	biolink:NamedThing	cyclo-ligase activity	Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti												EC:6.3.3.-		molecular_function											owl:Class	
GO:0039627	biolink:NamedThing	T=147 icosahedral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=147 symmetry. T=147 icosahedral capsid is composed of 12 pentameric and 1460 hexameric capsomeres for a total of 8820 capsid proteins.	got7fsn_ti							bf	2012-08-03T16:18:49Z						cellular_component											owl:Class	
GO:0046566	biolink:NamedThing	DOPA dioxygenase activity	Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid.	got7fsn_ti	dihydroxyphenylalanine dioxygenase activity											MetaCyc:RXN-8460		molecular_function											owl:Class	
GO:0036359	biolink:NamedThing	renal potassium excretion	The elimination by an organism of potassium in the urine.	got7fsn_ti	renal K+ elimination|renal K(+) excretion|renal potassium ion excretion						bf	2012-09-20T11:10:47Z						biological_process											owl:Class	
GO:1902586	biolink:NamedThing	multi-organism intercellular transport	An intercellular transport which involves another organism.	got7fsn_ti	multi organism intercellular transport						jl	2013-12-19T13:25:05Z						biological_process											owl:Class	
GO:0090327	biolink:NamedThing	negative regulation of locomotion involved in locomotory behavior	Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.	got7fsn_ti							tb	2010-05-14T10:26:58Z						biological_process											owl:Class	
GO:0070989	biolink:NamedThing	oxidative demethylation	The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.	got7fsn_ti							mah	2009-10-29T03:33:25Z						biological_process											owl:Class	
GO:0070988	biolink:NamedThing	demethylation	The process of removing one or more methyl groups from a molecule.	got7fsn_ti							mah	2009-10-29T03:12:51Z						biological_process											owl:Class	
GO:0021642	biolink:NamedThing	trochlear nerve formation	The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	got7fsn_ti	CN IV biosynthesis|CN IV formation													biological_process											owl:Class	
GO:0010050	biolink:NamedThing	vegetative phase change	Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.	got7fsn_ti														biological_process											owl:Class	
GO:0030736	biolink:NamedThing	phenol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+).	got7fsn_ti	PMT|S-adenosyl-L-methionine:phenol O-methyltransferase activity											KEGG_REACTION:R01239|RHEA:14809|EC:2.1.1.25|MetaCyc:PHENOL-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0038017	biolink:NamedThing	Wnt receptor internalization	A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell.	got7fsn_ti	Wnt receptor endocytosis						bf	2011-06-23T04:25:47Z						biological_process											owl:Class	
GO:0004915	biolink:NamedThing	interleukin-6 receptor activity	Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-6 receptor activity|IL-6R|gp130													molecular_function											owl:Class	
GO:0030943	biolink:NamedThing	mitochondrion targeting sequence binding	Binding to a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion.	got7fsn_ti	mitochondrial targeting sequence binding													molecular_function											owl:Class	
GO:0004526	biolink:NamedThing	ribonuclease P activity	Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.	got7fsn_ti	tRNA 5' leader endonuclease activity|RNase P											Reactome:R-HSA-5696810|Wikipedia:RNase_P|EC:3.1.26.5|MetaCyc:3.1.26.5-RXN		molecular_function											owl:Class	
GO:0035715	biolink:NamedThing	chemokine (C-C motif) ligand 2 binding	Binding to chemokine (C-C motif) ligand 2.	got7fsn_ti	CCL2 binding						bf	2011-03-03T04:24:24Z						molecular_function											owl:Class	
GO:0008854	biolink:NamedThing	exodeoxyribonuclease V activity	Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides.	got7fsn_ti	E. coli exonuclease V activity|exonuclease V activity|E. coli exonuclease V|RecBC deoxyribonuclease activity|gene recBC endoenzyme|gene recBCD enzymes|Escherichia coli exonuclease V|gene recBC DNase activity											EC:3.1.11.5|MetaCyc:3.1.11.5-RXN		molecular_function											owl:Class	
GO:0106212	biolink:NamedThing	centromere detachment from spindle pole body involved in meiotic chromosome organization	The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I.	got7fsn_ti	centromere detachment from spindle pole body involved in chromosome organization involved in meiotic cell cycle|centromere detachment from SPB involved in meiotic chromosome organization						hjd	2019-06-25T18:28:39Z						biological_process											owl:Class	
GO:0097128	biolink:NamedThing	cyclin D1-CDK4 complex	A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:48:36Z						cellular_component											owl:Class	
GO:0043641	biolink:NamedThing	novobiocin metabolic process	The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.	got7fsn_ti	novobiocin metabolism											Wikipedia:Novobiocin		biological_process											owl:Class	
GO:0050200	biolink:NamedThing	plasmalogen synthase activity	Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine.	got7fsn_ti	O-1-alkenylglycero-3-phosphorylcholine acyltransferase activity|lysoplasmenylcholine acyltransferase activity|1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase activity|acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase activity											EC:2.3.1.25|MetaCyc:PLASMALOGEN-SYNTHASE-RXN		molecular_function											owl:Class	
GO:1990430	biolink:NamedThing	extracellular matrix protein binding	Binding to a protein that is part of an extracellular matrix.	got7fsn_ti							jl	2014-07-29T14:57:07Z						molecular_function											owl:Class	
GO:1901771	biolink:NamedThing	daunorubicin biosynthetic process	The chemical reactions and pathways resulting in the formation of daunorubicin.	got7fsn_ti	daunorubicin formation|daunorubicin anabolism|daunorubicin biosynthesis|daunorubicin synthesis						yaf	2013-01-15T10:14:33Z						biological_process											owl:Class	
GO:0044597	biolink:NamedThing	daunorubicin metabolic process	The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer.	got7fsn_ti							jl	2012-05-01T03:09:51Z						biological_process											owl:Class	
GO:0014051	biolink:NamedThing	gamma-aminobutyric acid secretion	The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.	got7fsn_ti	GABA secretion													biological_process											owl:Class	
GO:0018264	biolink:NamedThing	isopeptide cross-linking via N-(L-isoaspartyl)-glycine	The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to produce N-(L-isoaspartyl)-glycine.	got7fsn_ti												RESID:AA0126		biological_process											owl:Class	
GO:0031688	biolink:NamedThing	A2B adenosine receptor binding	Binding to an A2B adenosine receptor.	got7fsn_ti	A2B adenosine receptor ligand													molecular_function											owl:Class	
GO:0075025	biolink:NamedThing	initiation of appressorium formation	The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	appressorium initiation on or near host|initiation of symbiont appressorium on or near host|initiation of appressorium by symbiont on or near host|initiation of appressorium on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0001165	biolink:NamedThing	RNA polymerase I cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase I. RNA polymerase I elements are referred to either enhancers or upstream control element (UCE, or alternately referred to as the upstream element).	got7fsn_ti	RNA polymerase I upstream control element sequence-specific DNA binding|RNA polymerase I upstream element sequence-specific DNA binding|RNA polymerase I enhancer sequence-specific DNA binding						krc	2011-01-31T05:29:59Z			GO:0001166			molecular_function											owl:Class	
GO:0002570	biolink:NamedThing	somatic diversification of immunoglobulin genes by N region addition	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.	got7fsn_ti	somatic diversification of antibody genes by N region addition													biological_process											owl:Class	
GO:0035822	biolink:NamedThing	gene conversion	A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18777					bf	2011-05-04T01:04:39Z						biological_process											owl:Class	
GO:0047638	biolink:NamedThing	albendazole monooxygenase activity	Catalysis of the reaction: albendazole + H(+) + NADPH + O(2) = albendazole S-oxide + H(2)O + NADP(+).	got7fsn_ti	albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)|albendazole sulfoxidase activity|albendazole oxidase activity											MetaCyc:ALBENDAZOLE-MONOOXYGENASE-RXN|KEGG_REACTION:R03712|RHEA:10796|EC:1.14.13.32		molecular_function											owl:Class	
GO:2001155	biolink:NamedThing	negative regulation of glycolytic fermentation to ethanol	Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol.	got7fsn_ti	negative regulation of glucose fermentation to ethanol|negative regulation of ethanol fermentation						mcc	2011-10-27T02:39:05Z						biological_process											owl:Class	
GO:0047940	biolink:NamedThing	glucuronokinase activity	Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H(+).	got7fsn_ti	glucurono-glucuronokinase activity|ATP:D-glucuronate 1-phosphotransferase activity|glucuronokinase (phosphorylating)											EC:2.7.1.43|RHEA:17005|MetaCyc:GLUCURONOKINASE-RXN|KEGG_REACTION:R01476		molecular_function											owl:Class	
GO:0072667	biolink:NamedThing	maintenance of protein location in vacuole	Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.	got7fsn_ti							mah	2011-02-14T02:56:57Z						biological_process											owl:Class	
GO:0060114	biolink:NamedThing	vestibular receptor cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.	got7fsn_ti	vestibular hair cell differentiation													biological_process											owl:Class	
GO:0006957	biolink:NamedThing	complement activation, alternative pathway	Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.	got7fsn_ti	complement cascade, alternative pathway													biological_process											owl:Class	
GO:0070459	biolink:NamedThing	prolactin secretion	The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.	got7fsn_ti														biological_process											owl:Class	
GO:0061459	biolink:NamedThing	L-arginine transmembrane transporter activity	Enables the stereospecific transfer of L-arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.	got7fsn_ti	ATP-dependent L-arginine transmembrane transporter activity|arginine-importing ATPase activity|arginine porter activity|ATPase-coupled L-arginine transmembrane transporter activity|L-arginine-importing ATPase activity						dph	2012-09-25T08:37:29Z			GO:0015598|GO:0102022			molecular_function											owl:Class	
GO:0048645	biolink:NamedThing	animal organ formation	The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.	got7fsn_ti	animal organ primordium initiation|initiation of an animal organ primordium													biological_process											owl:Class	
GO:0044775	biolink:NamedThing	DNA polymerase III, beta sliding clamp processivity factor complex	A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species.	got7fsn_ti							jl	2013-03-13T13:59:48Z						cellular_component											owl:Class	
GO:0045333	biolink:NamedThing	cellular respiration	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).	got7fsn_ti	oxidative metabolism|oxidative metabolic process|respiration											Wikipedia:Cellular_respiration		biological_process											owl:Class	
GO:0015980	biolink:NamedThing	energy derivation by oxidation of organic compounds	The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.	got7fsn_ti	chemoorganotrophy													biological_process											owl:Class	
GO:0061126	biolink:NamedThing	positive regulation of positive chemotaxis to cAMP by DIF-1	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.	got7fsn_ti							dph	2010-05-17T08:41:04Z						biological_process											owl:Class	
GO:0019961	biolink:NamedThing	interferon binding	Binding to an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent.	got7fsn_ti	IFN binding													molecular_function											owl:Class	
GO:0102647	biolink:NamedThing	D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity	Catalysis of the reaction: sedoheptulose 7-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-erythrose 4-phosphate.	got7fsn_ti												MetaCyc:RXN-15789		molecular_function											owl:Class	
GO:0016087	biolink:NamedThing	ecdysiostatic hormone activity	The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion.	got7fsn_ti														molecular_function											owl:Class	
GO:0045057	biolink:NamedThing	cisternal progression	The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna.	got7fsn_ti	cisternal maturation													biological_process											owl:Class	
GO:0007039	biolink:NamedThing	protein catabolic process in the vacuole	The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.	got7fsn_ti	vacuolar protein catabolism|vacuolar protein degradation|vacuolar protein catabolic process|vacuolar protein breakdown													biological_process											owl:Class	
GO:0046661	biolink:NamedThing	male sex differentiation	The establishment of the sex of a male organism by physical differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0019779	biolink:NamedThing	Atg8 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti	APG8 activating enzyme activity|APG7													molecular_function											owl:Class	
GO:0000428	biolink:NamedThing	DNA-directed RNA polymerase complex	A protein complex that possesses DNA-directed RNA polymerase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0030880	biolink:NamedThing	RNA polymerase complex	Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits.	got7fsn_ti	multisubunit RNA polymerase													cellular_component											owl:Class	
GO:0009232	biolink:NamedThing	riboflavin catabolic process	The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).	got7fsn_ti	vitamin B2 catabolism|vitamin B2 catabolic process|riboflavin breakdown|vitamin G catabolism|vitamin G catabolic process|riboflavin catabolism|riboflavin degradation													biological_process											owl:Class	
GO:0051558	biolink:NamedThing	phlobaphene metabolic process	The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.	got7fsn_ti	phlobaphene metabolism													biological_process											owl:Class	
GO:0102598	biolink:NamedThing	3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity	Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O.	got7fsn_ti												EC:1.14.14.123|RHEA:41472|MetaCyc:RXN-15382		molecular_function											owl:Class	
GO:0070250	biolink:NamedThing	mating projection membrane	The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone.	got7fsn_ti	shmoo membrane													cellular_component											owl:Class	
GO:0086015	biolink:NamedThing	SA node cell action potential	An action potential that occurs in a sinoatrial node cardiac muscle cell.	got7fsn_ti	sinus node cardiac muscle cell action potential|sinoatrial node cardiac muscle cell action potential|SAN cardiac muscle cell action potential|SA node cardiac muscle cell action potential						tb	2011-11-10T08:50:15Z						biological_process											owl:Class	
GO:0086001	biolink:NamedThing	cardiac muscle cell action potential	An action potential that occurs in a cardiac muscle cell.	got7fsn_ti							tb	2011-11-10T07:45:11Z						biological_process											owl:Class	
GO:0090546	biolink:NamedThing	chlorophyll fluorescence	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light.	got7fsn_ti							tb	2013-03-27T14:23:27Z						biological_process											owl:Class	
GO:0015850	biolink:NamedThing	organic hydroxy compound transport	The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom.	got7fsn_ti	organic alcohol transport													biological_process											owl:Class	
GO:0070516	biolink:NamedThing	CAK-ERCC2 complex	A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2.	got7fsn_ti	cyclin-dependent protein kinase activating kinase holoenzyme-ERCC2 complex													cellular_component											owl:Class	
GO:0072225	biolink:NamedThing	metanephric late distal convoluted tubule development	The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.	got7fsn_ti							mah	2010-03-18T03:37:04Z						biological_process											owl:Class	
GO:0072068	biolink:NamedThing	late distal convoluted tubule development	The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.	got7fsn_ti							mah	2010-01-25T04:15:50Z						biological_process											owl:Class	
GO:0097149	biolink:NamedThing	centralspindlin complex	A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).	got7fsn_ti							pr	2011-08-04T11:15:37Z						cellular_component											owl:Class	
GO:0033242	biolink:NamedThing	negative regulation of cellular amine catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.	got7fsn_ti	negative regulation of amine catabolism|negative regulation of amine breakdown|negative regulation of amine degradation													biological_process											owl:Class	
GO:0032133	biolink:NamedThing	chromosome passenger complex	A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin.	got7fsn_ti	CPC complex|CPC|chromosomal passenger complex													cellular_component											owl:Class	
GO:0047541	biolink:NamedThing	2-furoate-CoA ligase activity	Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H(+).	got7fsn_ti	2-furoyl coenzyme A synthetase activity|2-furoate:CoA ligase (AMP-forming)											EC:6.2.1.31|MetaCyc:2-FUROATE--COA-LIGASE-RXN|KEGG_REACTION:R02986|RHEA:19269		molecular_function											owl:Class	
GO:1990238	biolink:NamedThing	double-stranded DNA endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within a double-stranded deoxyribonucleic acid molecule by creating internal breaks.	got7fsn_ti	dsDNA-specific endodeoxyribonuclease activity						pg	2013-11-15T00:59:42Z						molecular_function											owl:Class	
GO:0043712	biolink:NamedThing	2-hydroxyisocaproate CoA-transferase activity	Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate.	got7fsn_ti	(R)-2-hydroxyisocaproate CoA-transferase activity|(R)-2-hydroxyisocaproate CoA transferase activity													molecular_function											owl:Class	
GO:0052691	biolink:NamedThing	UDP-arabinopyranose mutase activity	Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose.	got7fsn_ti	UDP-L-arabinose mutase activity|UDP-L-arabinopyranose furanomutase activity|UDP-L-Ara mutase activity|uridine-diphosphate-L-arabinose mutase activity|UDP-arabinopyranose pyranomutase activity											EC:5.4.99.30|MetaCyc:RXN-11552|RHEA:28350		molecular_function											owl:Class	
GO:0021755	biolink:NamedThing	eurydendroid cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts.	got7fsn_ti														biological_process											owl:Class	
GO:0071251	biolink:NamedThing	cellular response to silicon dioxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.	got7fsn_ti	cellular response to silica|cellular response to silox						mah	2009-12-03T03:09:41Z						biological_process											owl:Class	
GO:0061909	biolink:NamedThing	autophagosome-lysosome fusion	The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.	got7fsn_ti	autophagosome fusion|autophagosome-vacuole fusion						dph	2017-06-29T17:07:52Z						biological_process											owl:Class	
GO:0090646	biolink:NamedThing	mitochondrial tRNA processing	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group,  in the mitochondrion.	got7fsn_ti							tb	2015-06-12T15:57:13Z						biological_process											owl:Class	
GO:0097646	biolink:NamedThing	calcitonin family receptor signaling pathway	A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.	got7fsn_ti	calcitonin family receptor signalling pathway						pr	2014-09-09T17:48:05Z						biological_process											owl:Class	
GO:0035152	biolink:NamedThing	regulation of tube architecture, open tracheal system	Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.	got7fsn_ti	regulation of tracheal tube architecture													biological_process											owl:Class	
GO:0071666	biolink:NamedThing	Slit-Robo signaling complex	A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate.	got7fsn_ti	Slit-Robo signalling complex						mah	2010-02-12T03:35:28Z						cellular_component											owl:Class	
GO:0032992	biolink:NamedThing	protein-carbohydrate complex	A macromolecular complex containing separate protein and carbohydrate molecules.  Separate in this context means not covalently bound to each other.	got7fsn_ti					Macromolecular complexes in which the carbohydrate component is all covalently bound to protein are not considered protein carbohydrate complexes.									cellular_component											owl:Class	
GO:0034908	biolink:NamedThing	2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity	Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+.	got7fsn_ti												UM-BBD_reactionID:r0724|EC:1.14.12.-		molecular_function											owl:Class	
GO:0046911	biolink:NamedThing	metal chelating activity	The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.	got7fsn_ti	metal chelation|heavy metal chelation													molecular_function											owl:Class	
GO:0046872	biolink:NamedThing	metal ion binding	Binding to a metal ion.	got7fsn_ti	metal binding|heavy metal binding													molecular_function											owl:Class	
GO:1990579	biolink:NamedThing	peptidyl-serine trans-autophosphorylation	The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.	got7fsn_ti	serine transautophosphorylation|serine autophosphorylation in trans						bf	2014-12-09T09:20:08Z						biological_process											owl:Class	
GO:0036290	biolink:NamedThing	protein trans-autophosphorylation	The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer.	got7fsn_ti	trans-autophosphorylation						bf	2012-07-18T10:27:06Z						biological_process											owl:Class	
GO:0090077	biolink:NamedThing	foam cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	got7fsn_ti							tb	2009-09-15T03:46:30Z						biological_process											owl:Class	
GO:0102421	biolink:NamedThing	curcumin-4'-O-beta-D-gentiobioside 1,6-glucosyltransferase activity	Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13813		molecular_function											owl:Class	
GO:0045862	biolink:NamedThing	positive regulation of proteolysis	Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.	got7fsn_ti	up-regulation of proteolysis|positive regulation of peptidolysis|upregulation of proteolysis|activation of proteolysis|stimulation of proteolysis|up regulation of proteolysis													biological_process											owl:Class	
GO:0032270	biolink:NamedThing	positive regulation of cellular protein metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.	got7fsn_ti	positive regulation of cellular protein metabolism|up-regulation of cellular protein metabolic process|stimulation of cellular protein metabolic process|upregulation of cellular protein metabolic process|activation of cellular protein metabolic process|up regulation of cellular protein metabolic process													biological_process											owl:Class	
GO:0060235	biolink:NamedThing	lens induction in camera-type eye	Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens.	got7fsn_ti														biological_process											owl:Class	
GO:0035845	biolink:NamedThing	photoreceptor cell outer segment organization	A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.	got7fsn_ti	photoreceptor outer segment organization|photoreceptor cell outer segment organisation						bf	2011-05-10T10:44:09Z						biological_process											owl:Class	
GO:0018479	biolink:NamedThing	benzaldehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.	got7fsn_ti	benzaldehyde (NAD) dehydrogenase activity|benzaldehyde:NAD+ oxidoreductase activity											EC:1.2.1.28|MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN|RHEA:11840|UM-BBD_reactionID:r0269		molecular_function											owl:Class	
GO:0047082	biolink:NamedThing	3,9-dihydroxypterocarpan 6a-monooxygenase activity	Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H(+) + NADPH + O(2) = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(2)O + NADP(+). (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.	got7fsn_ti	(6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating)|3,9-dihydroxypterocarpan 6alpha-monooxygenase|3,9-dihydroxypterocarpan 6a-hydroxylase activity											RHEA:15321|MetaCyc:RXN-4505|KEGG_REACTION:R03452|EC:1.14.14.93		molecular_function											owl:Class	
GO:1905278	biolink:NamedThing	positive regulation of epithelial tube formation	Any process that activates or increases the frequency, rate or extent of epithelial tube formation.	got7fsn_ti	activation of epithelial tube formation|upregulation of epithelial tube formation|up-regulation of epithelial tube formation|up regulation of epithelial tube formation				An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-06-20T09:35:57Z						biological_process											owl:Class	
GO:0051045	biolink:NamedThing	negative regulation of membrane protein ectodomain proteolysis	Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.	got7fsn_ti	down regulation of membrane protein ectodomain proteolysis|downregulation of membrane protein ectodomain proteolysis|inhibition of membrane protein ectodomain proteolysis|down-regulation of membrane protein ectodomain proteolysis													biological_process											owl:Class	
GO:0042177	biolink:NamedThing	negative regulation of protein catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	got7fsn_ti	negative regulation of protein catabolism|negative regulation of protein breakdown|down regulation of protein catabolic process|inhibition of protein catabolic process|downregulation of protein catabolic process|negative regulation of protein degradation|down-regulation of protein catabolic process													biological_process											owl:Class	
GO:0045039	biolink:NamedThing	protein insertion into mitochondrial inner membrane	The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane.	got7fsn_ti	mitochondrial inner membrane protein import|protein transport into mitochondrial inner membrane|protein import into mitochondrial inner membrane	https://github.com/geneontology/go-ontology/issues/15800												biological_process											owl:Class	
GO:0015044	biolink:NamedThing	rubredoxin-NAD+ reductase activity	Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+.	got7fsn_ti	DPNH-rubredoxin reductase activity|NADH:rubredoxin oxidoreductase activity|dihydronicotinamide adenine dinucleotide--rubredoxin reductase activity|NADH--rubredoxin oxidoreductase activity|rubredoxin--NAD reductase activity|NADH--rubredoxin reductase activity|rubredoxin--nicotinamide adenine dinucleotide reductase activity|rubredoxin:NAD+ oxidoreductase activity|reduced nicotinamide adenine dinucleotide--rubredoxin reductase activity|NADH:rubredoxin reductase activity											EC:1.18.1.1|MetaCyc:RUBREDOXIN--NAD+-REDUCTASE-RXN|RHEA:18597		molecular_function											owl:Class	
GO:0015045	biolink:NamedThing	rubredoxin-NAD(P)+ reductase activity	Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.	got7fsn_ti	rubredoxin--nicotinamide adenine activity|NAD(P)H--rubredoxin oxidoreductase activity|dinucleotide phosphate reductase activity|rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity|NADPH:rubredoxin reductase activity|rubredoxin:NAD(P)+ oxidoreductase activity|NAD(P)--rubredoxin oxidoreductase activity											MetaCyc:RUBREDOXIN--NADP+-REDUCTASE-RXN|EC:1.18.1.4		molecular_function											owl:Class	
GO:0022004	biolink:NamedThing	midbrain-hindbrain boundary maturation during brain development	A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	got7fsn_ti														biological_process											owl:Class	
GO:0060790	biolink:NamedThing	tooth placode formation	The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.	got7fsn_ti							dph	2009-08-04T12:21:47Z						biological_process											owl:Class	
GO:0006599	biolink:NamedThing	phosphagen metabolic process	The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.	got7fsn_ti	phosphagen metabolism													biological_process											owl:Class	
GO:0060787	biolink:NamedThing	positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway	Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.	got7fsn_ti	positive regulation of posterior neural plate formation by FGF receptor signaling pathway|positive regulation of posterior neural plate formation by fibroblast growth factor receptor signalling pathway						dph	2009-08-04T09:48:31Z						biological_process											owl:Class	
GO:0008543	biolink:NamedThing	fibroblast growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.	got7fsn_ti	FGF receptor signaling pathway|fibroblast growth factor receptor signalling pathway|FGF receptor signalling pathway|FGFR signaling pathway													biological_process											owl:Class	
GO:0039502	biolink:NamedThing	suppression by virus of host type I interferon-mediated signaling pathway	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	inhibition of host interferon signaling pathway by virus|suppression by virus of host type I interferon-mediated signalling pathway|negative regulation by virus of host type I interferon-mediated signaling pathway|suppression by virus of host type I IFN-mediated signaling pathway						bf	2011-05-11T04:06:28Z				VZ:883		biological_process											owl:Class	
GO:0033871	biolink:NamedThing	[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.	got7fsn_ti	glucosaminyl 3-O-sulfotransferase 2 activity|heparin-glucosamine 3-sulfotransferase 2 activity|isoform/isozyme 2 (3-OST-2, HS3ST2)|heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity|glucosaminyl 3-O-sulfotransferase activity|3-OST-2|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 activity											MetaCyc:2.8.2.29-RXN|EC:2.8.2.29		molecular_function											owl:Class	
GO:0038120	biolink:NamedThing	CCL21-activated CCR7 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CCL21-activated CCR7 signalling pathway						bf	2012-03-22T11:47:24Z						biological_process											owl:Class	
GO:0048716	biolink:NamedThing	labrum morphogenesis	The process in which the anatomical structures of labrum are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0097178	biolink:NamedThing	ruffle assembly	The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42.	got7fsn_ti	membrane ruffle formation|membrane ruffling						pr	2011-10-16T01:46:09Z						biological_process											owl:Class	
GO:0031529	biolink:NamedThing	ruffle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.	got7fsn_ti	ruffle organization and biogenesis|ruffle organisation													biological_process											owl:Class	
GO:0047900	biolink:NamedThing	formate kinase activity	Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H(+).	got7fsn_ti	ATP:formate phosphotransferase activity											KEGG_REACTION:R00518|EC:2.7.2.6|MetaCyc:FORMATE-KINASE-RXN|RHEA:16009		molecular_function											owl:Class	
GO:0018429	biolink:NamedThing	copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide	The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide.	got7fsn_ti	copper incorporation into copper-sulphur cluster via heptakis-L-histidino tetracopper mu4-sulphide hydroxide											RESID:AA0298		biological_process											owl:Class	
GO:0102291	biolink:NamedThing	11alpha-hydroxy-beta-amyrin dehydrogenase activity	Catalysis of the reaction: 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11-oxo-beta-amyrin + 2 H2O + NADP.	got7fsn_ti												EC:1.14.14.152|MetaCyc:RXN-12682|RHEA:31719		molecular_function											owl:Class	
GO:0061759	biolink:NamedThing	alpha-ketoglutarate reductase activity	Catalysis of the reaction: 2-oxoglutarate + reduced acceptor = (S)-2-hydroxyglutarate + acceptor.	got7fsn_ti	D-2HG reductase activity|2-hydroxyglutarate dehydrogenase activity, reverse reaction|2-ketoglutarate reductase activity|2-oxoglutarate reductase activity						dph	2016-03-07T08:38:57Z				RHEA:21254		molecular_function											owl:Class	
GO:0051562	biolink:NamedThing	negative regulation of mitochondrial calcium ion concentration	Any process that decreases the concentration of calcium ions in mitochondria.	got7fsn_ti	reduction of calcium ion concentration in mitochondria|reduction of calcium ion concentration in mitochondrion|mitochondrial calcium ion concentration reduction|reduction of mitochondrial calcium ion concentration													biological_process											owl:Class	
GO:0051560	biolink:NamedThing	mitochondrial calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.	got7fsn_ti	mitochondrial calcium ion concentration regulation|calcium ion homeostasis in mitochondria|regulation of mitochondrial calcium ion concentration|regulation of calcium ion concentration in mitochondria|calcium ion homeostasis in mitochondrion|regulation of calcium ion concentration in mitochondrion													biological_process											owl:Class	
GO:1990444	biolink:NamedThing	F-box domain binding	Binding to an F-box domain of a protein.	got7fsn_ti							bf	2014-08-05T13:45:14Z						molecular_function											owl:Class	
GO:0002412	biolink:NamedThing	antigen transcytosis by M cells in mucosal-associated lymphoid tissue	The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT.	got7fsn_ti	antigen transport by M cells in MALT|antigen transcytosis by M cells in MALT|antigen transport by M cells in mucosal-associated lymphoid tissue													biological_process											owl:Class	
GO:0140488	biolink:NamedThing	heme receptor activity	Binding specifically to heme to deliver it to a transport vesicle.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19699					pg	2020-06-29T14:16:16Z						molecular_function											owl:Class	
GO:0031140	biolink:NamedThing	induction of conjugation upon nutrient starvation	The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients.	got7fsn_ti														biological_process											owl:Class	
GO:1900566	biolink:NamedThing	chanoclavine-I biosynthetic process	The chemical reactions and pathways resulting in the formation of chanoclavine-I.	got7fsn_ti	chanoclavine-I formation|chanoclavine-I biosynthesis|chanoclavine-I synthesis|chanoclavine-I anabolism						di	2012-05-15T06:30:55Z						biological_process											owl:Class	
GO:0047731	biolink:NamedThing	catechol oxidase (dimerizing) activity	Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.	got7fsn_ti	catechol:oxygen oxidoreductase (dimerizing)											EC:1.1.3.14|MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN|RHEA:12809		molecular_function											owl:Class	
GO:0070457	biolink:NamedThing	D-galactose-1-phosphate phosphatase activity	Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0072111	biolink:NamedThing	cell proliferation involved in kidney development	The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.	got7fsn_ti							mah	2010-02-22T10:48:45Z						biological_process											owl:Class	
GO:0020033	biolink:NamedThing	antigenic variation	Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.	got7fsn_ti	surface antigen variation	https://github.com/geneontology/go-ontology/issues/18357									GO:0020034	Wikipedia:Antigenic_variation		biological_process											owl:Class	
GO:0023030	biolink:NamedThing	MHC class Ib protein binding, via antigen binding groove	Binding to a major histocompatibility complex class Ib molecules via the antigen binding groove.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0023029	biolink:NamedThing	MHC class Ib protein binding	Binding to a major histocompatibility complex class Ib molecules.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0031119	biolink:NamedThing	tRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0030430	biolink:NamedThing	host cell cytoplasm	The cytoplasm of a host cell.	got7fsn_ti	other organism cytoplasm						pr	2014-12-01T14:14:21Z			GO:0097679			cellular_component											owl:Class	
GO:0033853	biolink:NamedThing	aspartate-prephenate aminotransferase activity	Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate.	got7fsn_ti	L-aspartate:prephenate aminotransferase activity|L-arogenate:oxaloacetate aminotransferase activity|PAT|prephenate aspartate aminotransferase activity|prephenate transaminase activity											RHEA:20445|MetaCyc:PREPHENATE-ASP-TRANSAMINE-RXN|EC:2.6.1.78		molecular_function											owl:Class	
GO:0047328	biolink:NamedThing	acyl-phosphate-hexose phosphotransferase activity	Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid.	got7fsn_ti	acyl-phosphate:D-hexose phosphotransferase activity|hexose phosphate:hexose phosphotransferase activity											MetaCyc:2.7.1.61-RXN|RHEA:13077|EC:2.7.1.61		molecular_function											owl:Class	
GO:0034212	biolink:NamedThing	peptide N-acetyltransferase activity	Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.	got7fsn_ti												Reactome:R-HSA-3371554		molecular_function											owl:Class	
GO:0033964	biolink:NamedThing	glycosphingolipid deacylase activity	Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.	got7fsn_ti	glycosphingolipid ceramide deacylase activity|glycosphingolipid amidohydrolase activity											EC:3.5.1.69|MetaCyc:3.5.1.69-RXN		molecular_function											owl:Class	
GO:0047901	biolink:NamedThing	formyl-CoA hydrolase activity	Catalysis of the reaction: formyl-CoA + H(2)O = CoA + formate + H(+).	got7fsn_ti	formyl coenzyme A hydrolase activity											KEGG_REACTION:R00521|RHEA:19741|EC:3.1.2.10|MetaCyc:FORMYL-COA-HYDROLASE-RXN		molecular_function											owl:Class	
GO:0048679	biolink:NamedThing	regulation of axon regeneration	Any process that modulates the frequency, rate or extent of axon regeneration.	got7fsn_ti														biological_process											owl:Class	
GO:0090642	biolink:NamedThing	microsporidian-type exospore	The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore.	got7fsn_ti							tb	2015-05-04T14:17:06Z						cellular_component											owl:Class	
GO:0018070	biolink:NamedThing	peptidyl-serine phosphopantetheinylation	The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.	got7fsn_ti												RESID:AA0150		biological_process											owl:Class	
GO:0008542	biolink:NamedThing	visual learning	Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.	got7fsn_ti	spatial learning													biological_process											owl:Class	
GO:0008974	biolink:NamedThing	phosphoribulokinase activity	Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H(+).	got7fsn_ti	5-phosphoribulose kinase activity|PRuK|ribulose phosphate kinase activity|PRK|PKK|phosphoribulokinase (phosphorylating)|ATP:D-ribulose-5-phosphate 1-phosphotransferase activity|phosphopentokinase activity|ribulose-5-phosphate kinase activity											MetaCyc:PHOSPHORIBULOKINASE-RXN|EC:2.7.1.19|RHEA:19365|KEGG_REACTION:R01523		molecular_function											owl:Class	
GO:0001614	biolink:NamedThing	purinergic nucleotide receptor activity	Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	P2 receptor|purinoceptor|purinoreceptor|purinergic receptor activity						bf	2010-10-22T10:57:12Z			GO:0035586			molecular_function											owl:Class	
GO:1990360	biolink:NamedThing	PKM2 protein kinase complex	A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer.	got7fsn_ti	PKM2-SAICAR protein kinase complex|PKM2-SAICAR complex						bhm	2014-04-17T14:03:36Z						cellular_component											owl:Class	
GO:1902911	biolink:NamedThing	protein kinase complex	A protein complex which is capable of protein kinase activity.	got7fsn_ti					An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).		bhm	2014-04-17T13:52:40Z						cellular_component											owl:Class	
GO:0009556	biolink:NamedThing	microsporogenesis	The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores.	got7fsn_ti	microspore development													biological_process											owl:Class	
GO:0051979	biolink:NamedThing	alginic acid acetylation	The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate.	got7fsn_ti	alginate acetylation													biological_process											owl:Class	
GO:0042120	biolink:NamedThing	alginic acid metabolic process	The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).	got7fsn_ti	alginic acid metabolism|alginate metabolism|alginate metabolic process													biological_process											owl:Class	
GO:0048011	biolink:NamedThing	neurotrophin TRK receptor signaling pathway	A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	TrkB signaling pathway|TrkC signaling pathway|tropomyosin-receptor-kinase signaling|TrkA signaling pathway													biological_process											owl:Class	
GO:0140018	biolink:NamedThing	regulation of cytoplasmic translational fidelity	Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code.	got7fsn_ti							pg	2017-04-06T12:27:10Z						biological_process											owl:Class	
GO:0006450	biolink:NamedThing	regulation of translational fidelity	Any process that modulates the ability of the translational apparatus to interpret the genetic code.	got7fsn_ti	regulation of translational accuracy										GO:0000029			biological_process											owl:Class	
GO:0106106	biolink:NamedThing	cold-induced thermogenesis	The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.	got7fsn_ti	CIT						hjd	2018-03-21T20:30:52Z						biological_process											owl:Class	
GO:0045138	biolink:NamedThing	nematode male tail tip morphogenesis	The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.	got7fsn_ti	male tail morphogenesis|male tail tip morphogenesis|tail tip morphogenesis													biological_process											owl:Class	
GO:0008718	biolink:NamedThing	D-amino-acid dehydrogenase activity	Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor.	got7fsn_ti	D-amino-acid:acceptor oxidoreductase (deaminating)|D-amino-acid:(acceptor) oxidoreductase (deaminating)											MetaCyc:DAADEHYDROG-RXN|RHEA:18125		molecular_function											owl:Class	
GO:0030691	biolink:NamedThing	Noc2p-Noc3p complex	A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis.	got7fsn_ti					Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.									cellular_component											owl:Class	
GO:0052373	biolink:NamedThing	suppression of symbiont entry into host by host	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	downregulation by organism of entry into other organism during symbiotic interaction|down regulation by organism of entry into other organism during symbiotic interaction|negative regulation by organism of entry into other organism involved in symbiotic interaction|down-regulation by organism of entry into other organism during symbiotic interaction|negative regulation by organism of entry into other organism during symbiotic interaction|inhibition by organism of entry into other organism during symbiotic interaction													biological_process											owl:Class	
GO:0018504	biolink:NamedThing	cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+.	got7fsn_ti	cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase activity|cis-benzene glycol dehydrogenase activity|cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase activity											RHEA:15457|EC:1.3.1.19|MetaCyc:1.3.1.19-RXN|UM-BBD_enzymeID:e0060		molecular_function											owl:Class	
GO:0033537	biolink:NamedThing	ajugose biosynthetic process using galactinol:raffinose galactosyltransferase	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide.	got7fsn_ti	ajugose biosynthesis using galactinol:raffinose galactosyltransferase|ajugose formation using galactinol:raffinose galactosyltransferase|ajugose anabolism using galactinol:raffinose galactosyltransferase|ajugose synthesis using galactinol:raffinose galactosyltransferase											MetaCyc:PWY-5342		biological_process											owl:Class	
GO:0033536	biolink:NamedThing	ajugose biosynthetic process	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	ajugose synthesis|ajugose anabolism|ajugose formation|ajugose biosynthesis													biological_process											owl:Class	
GO:0061128	biolink:NamedThing	positive regulation of chemotaxis to cAMP by DIF-2	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.	got7fsn_ti							dph	2010-05-17T08:48:17Z						biological_process											owl:Class	
GO:0061124	biolink:NamedThing	positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.	got7fsn_ti							dph	2010-05-17T08:33:40Z						biological_process											owl:Class	
GO:0010954	biolink:NamedThing	positive regulation of protein processing	Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.	got7fsn_ti	positive regulation of protein maturation by peptide bond cleavage						tb	2009-04-27T12:09:13Z						biological_process											owl:Class	
GO:1903319	biolink:NamedThing	positive regulation of protein maturation	Any process that activates or increases the frequency, rate or extent of protein maturation.	got7fsn_ti	upregulation of protein maturation|activation of protein maturation|up regulation of protein maturation|up-regulation of protein maturation						vw	2014-08-18T12:59:23Z						biological_process											owl:Class	
GO:0008748	biolink:NamedThing	N-ethylmaleimide reductase activity	Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+.	got7fsn_ti												RHEA:35523|MetaCyc:RXN0-5101		molecular_function											owl:Class	
GO:0030536	biolink:NamedThing	larval feeding behavior	Feeding behavior in a larval (immature) organism.	got7fsn_ti	larval feeding behaviour				See also the biological process term 'feeding behavior ; GO:0007631'.									biological_process											owl:Class	
GO:0035093	biolink:NamedThing	spermatogenesis, exchange of chromosomal proteins	The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin.	got7fsn_ti	somatic histone exchange|somatic histone replacement													biological_process											owl:Class	
GO:0071905	biolink:NamedThing	protein N-linked glucosylation via asparagine	A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue.	got7fsn_ti	protein amino acid N-linked glucosylation via asparagine						mah	2010-09-15T03:54:25Z				RESID:AA0421		biological_process											owl:Class	
GO:0008781	biolink:NamedThing	N-acylneuraminate cytidylyltransferase activity	Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate.	got7fsn_ti	CMP-NANA synthetase activity|cytidine monophosphosialic acid synthetase activity|CMP-NeuAc synthetase activity|CTP:N-acylneuraminate cytidylyltransferase activity|CMP-Neu5Ac synthetase activity|CMP-sialate synthetase activity|CMP-N-acetylneuraminic acid synthase activity|CMP-sialate synthase activity|CMP-sialate diphosphorylase activity|cytidine monophosphoacetylneuraminic synthetase activity|CMP-sialic acid synthetase activity|CMP-N-acetylneuraminate synthetase activity|acetylneuraminate cytidylyltransferase activity|cytidine monophosphosialate pyrophosphorylase activity|acylneuraminate cytidyltransferase activity|CMP-N-acetylneuraminate synthase activity|cytidine 5'-monophospho-N-acetylneuraminic acid synthetase activity|CMP-N-acetylneuraminic acid synthetase activity|CMP-sialate pyrophosphorylase activity|CMP-sialic synthetase activity|CMP-NeuNAc synthetase activity|cytidine 5-monophosphate N-acetylneuraminic acid synthetase activity|cytidine monophosphosialate synthetase activity|cytidine 5'-monophosphosialic acid synthetase activity											EC:2.7.7.43|MetaCyc:ACYLNEURAMINATE-CYTIDYLYLTRANSFERASE-RXN|Reactome:R-HSA-4084982|RHEA:11344		molecular_function											owl:Class	
GO:0047933	biolink:NamedThing	glucose-1,6-bisphosphate synthase activity	Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H(+).	got7fsn_ti	glucose-1,6-bisphosphate synthetase activity|glucose 1,6-diphosphate synthase activity|3-phospho-D-glyceroyl-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity|3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase activity											RHEA:16769|MetaCyc:GLUCOSE-16-BISPHOSPHATE-SYNTHASE-RXN|KEGG_REACTION:R01660|Reactome:R-HSA-8955760|EC:2.7.1.106		molecular_function											owl:Class	
GO:0070141	biolink:NamedThing	response to UV-A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.	got7fsn_ti	response to UVA light stimulus|response to UVA radiation stimulus|response to UV-A radiation stimulus|response to UV-A light stimulus													biological_process											owl:Class	
GO:0045728	biolink:NamedThing	respiratory burst after phagocytosis	A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity.	got7fsn_ti	metabolic burst after phagocytosis|oxidative burst after phagocytosis													biological_process											owl:Class	
GO:0002679	biolink:NamedThing	respiratory burst involved in defense response	A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	got7fsn_ti														biological_process											owl:Class	
GO:0110128	biolink:NamedThing	phloem sucrose unloading	The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.	got7fsn_ti							kmv	2018-09-07T21:38:52Z						biological_process											owl:Class	
GO:0015770	biolink:NamedThing	sucrose transport	The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.	got7fsn_ti														biological_process											owl:Class	
GO:0046208	biolink:NamedThing	spermine catabolic process	The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.	got7fsn_ti	spermine breakdown|spermine degradation|spermine catabolism													biological_process											owl:Class	
GO:0033274	biolink:NamedThing	response to vitamin B2	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.	got7fsn_ti	response to riboflavin													biological_process											owl:Class	
GO:0033053	biolink:NamedThing	D-glutamine metabolic process	The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid.	got7fsn_ti	D-glutamine metabolism													biological_process											owl:Class	
GO:0103079	biolink:NamedThing	2-(3'-methylthio)propylmalate synthase activity	Catalysis of the reaction: 5-methylthio-2-oxopentanoate + acetyl-CoA + H2O <=> H+ + 2-(3-methylthiopropyl)malate + coenzyme A.	got7fsn_ti												RHEA:25605|MetaCyc:RXNQT-4163		molecular_function											owl:Class	
GO:0097429	biolink:NamedThing	amino acid ligation activity by nonribosomal peptide synthase	Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.	got7fsn_ti							pr	2012-11-16T12:34:22Z						molecular_function											owl:Class	
GO:0032982	biolink:NamedThing	myosin filament	A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament.	got7fsn_ti	thick filament|myosin thick filament													cellular_component											owl:Class	
GO:0021809	biolink:NamedThing	neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration	Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration.	got7fsn_ti	neurotrophic factor signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0021807	biolink:NamedThing	motogenic signaling initiating cell movement in cerebral cortex	The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex.	got7fsn_ti	motogenic signalling initiating cell movement in the cerebral cortex													biological_process											owl:Class	
GO:0008803	biolink:NamedThing	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity	Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP + 2 H(+).	got7fsn_ti	diadenosine tetraphosphate hydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase activity|Ap(4)A hydrolase activity|diadenosinetetraphosphatase (symmetrical) activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase activity|diadenosine tetraphosphatase (symmetrical)|dinucleosidetetraphosphatase (symmetrical) activity|bis(5'-adenosyl) tetraphosphatase activity|diadenosine polyphosphate hydrolase activity|symmetrical diadenosine tetraphosphate hydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphatase activity|dinucleosidetetraphosphate (symmetrical)|adenosine tetraphosphate phosphodiesterase activity|1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity|Ap4A hydrolase activity|P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity											KEGG_REACTION:R00125|RHEA:24252|MetaCyc:3.6.1.41-RXN|EC:3.6.1.41		molecular_function											owl:Class	
GO:0003175	biolink:NamedThing	tricuspid valve development	The progression of the tricuspid valve over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-08T11:18:12Z						biological_process											owl:Class	
GO:0090507	biolink:NamedThing	phenylethylamine metabolic process involved in synaptic transmission	The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission.	got7fsn_ti							tb	2012-11-15T15:06:08Z						biological_process											owl:Class	
GO:0006458	biolink:NamedThing	'de novo' protein folding	The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure.	got7fsn_ti	nascent chain protein folding													biological_process											owl:Class	
GO:0022006	biolink:NamedThing	zona limitans intrathalamica formation	The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon.	got7fsn_ti	zli biosynthesis|zli formation													biological_process											owl:Class	
GO:0060280	biolink:NamedThing	negative regulation of ovulation	Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.	got7fsn_ti														biological_process											owl:Class	
GO:0102535	biolink:NamedThing	ladanein 6-O-methyltransferase activity	Catalysis of the reaction: ladanein + S-adenosyl-L-methionine  <=> H+ + salvigenin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-14752		molecular_function											owl:Class	
GO:0140526	biolink:NamedThing	double membrane vesicle viral factory assembly	A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19943					pg	2020-09-29T08:26:51Z						biological_process											owl:Class	
GO:0035870	biolink:NamedThing	dITP diphosphatase activity	Catalysis of the reaction: dITP + H2O = dIMP + diphosphate.	got7fsn_ti	dITP pyrophosphatase activity|2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase activity|deoxyinosine triphosphate pyrophosphatase activity						bf	2011-05-26T11:32:26Z				RHEA:28342|EC:3.6.1.66|MetaCyc:RXN0-1602|Reactome:R-HSA-2509838|KEGG_REACTION:R03531		molecular_function											owl:Class	
GO:0098801	biolink:NamedThing	regulation of renal system process	Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.	got7fsn_ti														biological_process											owl:Class	
GO:0047461	biolink:NamedThing	(+)-delta-cadinene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.	got7fsn_ti	D-cadinene synthase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)											RHEA:19525|EC:4.2.3.13|MetaCyc:4.6.1.11-RXN		molecular_function											owl:Class	
GO:0033259	biolink:NamedThing	plastid DNA replication	The process in which new strands of DNA are synthesized in a plastid.	got7fsn_ti	replication of plastid DNA|plastid DNA synthesis													biological_process											owl:Class	
GO:0047248	biolink:NamedThing	nuatigenin 3-beta-glucosyltransferase activity	Catalysis of the reaction: nuatigenin + UDP-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP.	got7fsn_ti	UDPglucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity|UDP-glucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-nuatigenin glucosyltransferase activity|nuatigenin 3beta-glucosyltransferase activity											RHEA:19329|EC:2.4.1.192|KEGG_REACTION:R04577|MetaCyc:2.4.1.192-RXN		molecular_function											owl:Class	
GO:0015375	biolink:NamedThing	glycine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).	got7fsn_ti											GO:0015656	Reactome:R-HSA-5660840|Reactome:R-HSA-444120		molecular_function											owl:Class	
GO:0072377	biolink:NamedThing	blood coagulation, common pathway	A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.	got7fsn_ti					See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.		mah	2010-11-22T03:01:12Z						biological_process											owl:Class	
GO:0061417	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	got7fsn_ti							dph	2012-01-23T01:02:10Z						biological_process											owl:Class	
GO:0001788	biolink:NamedThing	antibody-dependent cellular cytotoxicity	Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.	got7fsn_ti	antibody dependent cell death|type VI hypersensitivity|antibody dependent cell killing|antibody-dependent cell killing|antibody-dependent cell death|ADCC											Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity|Wikipedia:Antibody-dependent_cellular_cytotoxicity		biological_process											owl:Class	
GO:0001794	biolink:NamedThing	type IIa hypersensitivity	An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.	got7fsn_ti					Note that some type IIb hypersensitivity responses (GO:0001795) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIa hypersensitivity.									biological_process											owl:Class	
GO:0051598	biolink:NamedThing	meiotic recombination checkpoint signaling	A signaling process that contributes to a meiotic recombination checkpoint, that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.	got7fsn_ti	signal transduction involved in meiotic recombination checkpoint|meiotic recombination checkpoint|pachytene checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072462			biological_process											owl:Class	
GO:0033313	biolink:NamedThing	meiotic cell cycle checkpoint signaling	A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.	got7fsn_ti	meiotic cell cycle checkpoint|signal transduction involved in meiotic cell cycle checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072411			biological_process											owl:Class	
GO:0047942	biolink:NamedThing	glutamate-ethylamine ligase activity	Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H(+) + phosphate.	got7fsn_ti	L-glutamate:ethylamine ligase (ADP-forming)|N5-ethylglutamine synthetase activity|N5-ethyl-L-glutamine synthetase activity|theanine synthetase activity|N(5)-ethyl-L-glutamine synthetase activity											RHEA:20525|KEGG_REACTION:R02929|EC:6.3.1.6|MetaCyc:GLUTAMATE--ETHYLAMINE-LIGASE-RXN		molecular_function											owl:Class	
GO:0034434	biolink:NamedThing	sterol esterification	A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol).	got7fsn_ti														biological_process											owl:Class	
GO:0052040	biolink:NamedThing	modulation by symbiont of host programmed cell death	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host non-apoptotic programmed cell death|modulation of host PCD										GO:0052152			biological_process											owl:Class	
GO:0102326	biolink:NamedThing	2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O <=> 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+.	got7fsn_ti												MetaCyc:RXN-13171		molecular_function											owl:Class	
GO:0004120	biolink:NamedThing	photoreceptor cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide.	got7fsn_ti														molecular_function											owl:Class	
GO:0031963	biolink:NamedThing	cortisol receptor activity	Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function.	got7fsn_ti					For cortisol receptors that act in the nucleus to regulate transcription, consider also annotating to the terms: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ; GO:0038049' or ligand-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038049'.									molecular_function											owl:Class	
GO:0035566	biolink:NamedThing	regulation of metanephros size	Any process that modulates the size of a metanephric kidney.	got7fsn_ti	regulation of metanephric kidney size						bf	2010-07-23T11:34:06Z						biological_process											owl:Class	
GO:0047330	biolink:NamedThing	polyphosphate-glucose phosphotransferase activity	Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate.	got7fsn_ti	polyphosphate-D-(+)-glucose-6-phosphotransferase activity|polyphosphate:D-glucose 6-phosphotransferase activity|polyphosphate glucokinase activity|polyphosphate-glucose 6-phosphotransferase activity											MetaCyc:2.7.1.63-RXN|EC:2.7.1.63|RHEA:22036		molecular_function											owl:Class	
GO:0050214	biolink:NamedThing	progesterone monooxygenase activity	Catalysis of the reaction: AH(2) + O(2) + progesterone = A + H(2)O + testosterone acetate.	got7fsn_ti	progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|progesterone hydroxylase activity											EC:1.14.99.4|MetaCyc:PROGESTERONE-MONOOXYGENASE-RXN|KEGG_REACTION:R02212|RHEA:11984		molecular_function											owl:Class	
GO:0005137	biolink:NamedThing	interleukin-5 receptor binding	Binding to an interleukin-5 receptor.	got7fsn_ti	interleukin-5 receptor ligand|IL-5													molecular_function											owl:Class	
GO:0043855	biolink:NamedThing	cyclic nucleotide-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	cyclic nucleotide activated ion channel activity|cyclic nucleotide gated ion channel activity|cyclic nucleotide-activated ion channel activity													molecular_function											owl:Class	
GO:0031484	biolink:NamedThing	myosin XIV complex	A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.	got7fsn_ti														cellular_component											owl:Class	
GO:0097130	biolink:NamedThing	cyclin D3-CDK4 complex	A protein complex consisting of cyclin D3 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:54:17Z						cellular_component											owl:Class	
GO:0062155	biolink:NamedThing	curli secretion complex	A protein-containing complex that serves as a channel for the secretion of curli. Curli are a fibers that serve as a major component of the extracellular matrix of pellicle biofilms.	got7fsn_ti							dph	2019-09-20T14:05:13Z						cellular_component											owl:Class	
GO:0097659	biolink:NamedThing	nucleic acid-templated transcription	The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		pr	2014-10-01T13:49:27Z						biological_process											owl:Class	
GO:0002213	biolink:NamedThing	defense response to insect	A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.	got7fsn_ti	physiological defense response to insect										GO:0002214			biological_process											owl:Class	
GO:0051804	biolink:NamedThing	positive regulation of cytolysis in other organism involved in symbiotic interaction	Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	up-regulation of cytolysis of cells in other organism during symbiotic interaction|upregulation of cytolysis of cells in other organism during symbiotic interaction|stimulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism involved in symbiotic interaction|up regulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism during symbiotic interaction|activation of cytolysis of cells in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0102792	biolink:NamedThing	sinapaldehyde:NAD(P)+ oxidoreductase activity	Catalysis of the reaction: sinapoyl aldehyde + NADP + H2O <=> 2 H+ + trans-sinapate + NADPH.	got7fsn_ti												MetaCyc:RXN-8014		molecular_function											owl:Class	
GO:0031950	biolink:NamedThing	negative regulation of glucocorticoid catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.	got7fsn_ti	downregulation of glucocorticoid catabolic process|down regulation of glucocorticoid catabolic process|inhibition of glucocorticoid catabolic process|down-regulation of glucocorticoid catabolic process													biological_process											owl:Class	
GO:0097007	biolink:NamedThing	4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity	Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone.	got7fsn_ti	4,8,12-trimethyl-1,3,7,11-tridecatetraene synthase activity|TMTT synthase activity						pr	2011-03-16T04:37:20Z				MetaCyc:RXN-8620|RHEA:13545		molecular_function											owl:Class	
GO:0102829	biolink:NamedThing	ajugose synthase activity	Catalysis of the reaction: 2 verbascose <=> ajugose + stachyose.	got7fsn_ti												MetaCyc:RXN-8285		molecular_function											owl:Class	
GO:0140546	biolink:NamedThing	defense response to symbiont	Reactions triggered in response to the presence of a symbiont that act to protect the cell or organism from damage caused by that symbiont.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20261					pg	2020-11-11T17:19:06Z						biological_process											owl:Class	
GO:0102759	biolink:NamedThing	campestanol hydroxylase activity	Catalysis of the reaction: H+ + campestanol + O2 + NADPH <=> 6-deoxycathasterone + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-773		molecular_function											owl:Class	
GO:0102602	biolink:NamedThing	cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity	Catalysis of the reaction: 16beta-hydroxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P).	got7fsn_ti												MetaCyc:RXN-15386		molecular_function											owl:Class	
GO:0008219	biolink:NamedThing	cell death	Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).	got7fsn_ti	necrosis|accidental cell death				This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.									biological_process											owl:Class	
GO:0052018	biolink:NamedThing	modulation by symbiont of RNA levels in host	The alteration by an organism of the levels of RNA in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host RNA levels													biological_process											owl:Class	
GO:0070675	biolink:NamedThing	hypoxanthine oxidase activity	Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.	got7fsn_ti	xanthine oxidoreductase activity|hypoxanthine-xanthine oxidase activity|hypoxanthine:O(2) oxidoreductase activity|hypoxanthine:O2 oxidoreductase activity|hypoxanthine:oxygen oxidoreductase activity|schardinger enzyme|Schardinger enzyme activity						mah	2009-05-29T01:12:55Z						molecular_function											owl:Class	
GO:0050680	biolink:NamedThing	negative regulation of epithelial cell proliferation	Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.	got7fsn_ti	down-regulation of epithelial cell proliferation|downregulation of epithelial cell proliferation|inhibition of epithelial cell proliferation|down regulation of epithelial cell proliferation													biological_process											owl:Class	
GO:0021893	biolink:NamedThing	cerebral cortex GABAergic interneuron fate commitment	The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0071665	biolink:NamedThing	gamma-catenin-TCF7L2 complex	A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.	got7fsn_ti	plakoglobin-TCF4 complex|gamma-catenin-TCF4 complex						mah	2010-02-12T03:23:08Z						cellular_component											owl:Class	
GO:0060912	biolink:NamedThing	cardiac cell fate specification	The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	got7fsn_ti	cardiocyte cell fate specification						dph	2009-09-17T08:53:21Z						biological_process											owl:Class	
GO:0044869	biolink:NamedThing	negative regulation by host of viral exo-alpha-sialidase activity	The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.	got7fsn_ti							jl	2014-09-18T14:13:51Z						biological_process											owl:Class	
GO:0044866	biolink:NamedThing	modulation by host of viral exo-alpha-sialidase activity	The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.	got7fsn_ti							jl	2014-09-18T11:28:18Z						biological_process											owl:Class	
GO:0033988	biolink:NamedThing	bile-acid 7alpha-dehydratase activity	Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O.	got7fsn_ti	7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase (12alpha-hydroxy-3-oxochola-4,6-dienoate-forming) activity|7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase activity|BA7 alpha dehydratase activity											EC:4.2.1.106|KEGG_REACTION:R07318|MetaCyc:4.2.1.106-RXN|RHEA:10436		molecular_function											owl:Class	
GO:0004446	biolink:NamedThing	inositol-hexakisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate.	got7fsn_ti	1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity|MIPP activity|multiple inositol-polyphosphate phosphatase activity|inositol tetrakisphosphate phosphomonoesterase activity											EC:3.1.3.62|MetaCyc:RXN-7920		molecular_function											owl:Class	
GO:0036529	biolink:NamedThing	protein deglycation, glyoxal removal	The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein.	got7fsn_ti	protein deglycation of glyoxal-glycated protein						bf	2016-08-04T10:41:25Z						biological_process											owl:Class	
GO:0046295	biolink:NamedThing	glycolate biosynthetic process	The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid).	got7fsn_ti	glycolate synthesis|glycolate biosynthesis|glycolate anabolism|glycolate formation													biological_process											owl:Class	
GO:0002350	biolink:NamedThing	peripheral B cell positive selection	Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.	got7fsn_ti	peripheral B-cell positive selection|peripheral B-lymphocyte positive selection|peripheral B lymphocyte positive selection													biological_process											owl:Class	
GO:0018232	biolink:NamedThing	peptide cross-linking via S-(L-isoglutamyl)-L-cysteine	The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link.	got7fsn_ti												RESID:AA0108		biological_process											owl:Class	
GO:0000915	biolink:NamedThing	actomyosin contractile ring assembly	The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.	got7fsn_ti	cytokinesis, actomyosin contractile ring formation|constriction ring assembly|contractile ring assembly|cytokinesis, contractile ring assembly|cytokinesis, actomyosin ring biosynthesis|cytokinesis, actomyosin contractile ring assembly|cytokinesis, actomyosin ring formation										GO:0045573			biological_process											owl:Class	
GO:0035439	biolink:NamedThing	halimadienyl-diphosphate synthase activity	Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate.	got7fsn_ti	halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing)|halimadienyl diphosphate synthase activity						bf	2010-04-09T02:59:35Z				RHEA:25621|EC:5.5.1.16		molecular_function											owl:Class	
GO:0099048	biolink:NamedThing	CRISPR-cas system	An adaptive immune response of bacteria that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci.	got7fsn_ti														biological_process											owl:Class	
GO:1901925	biolink:NamedThing	negative regulation of protein import into nucleus during spindle assembly checkpoint	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).	got7fsn_ti	Kap121p transport inhibitory pathway|negative regulation of protein import into nucleus during mitotic cell cycle spindle assembly checkpoint|KTIP						pr	2013-02-17T20:55:16Z						biological_process											owl:Class	
GO:0044018	biolink:NamedThing	histone acetyltransferase activity (H3-K36 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K36 specific)													molecular_function											owl:Class	
GO:0060457	biolink:NamedThing	negative regulation of digestive system process	Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0003088	biolink:NamedThing	positive regulation of the force of heart contraction by circulating epinephrine	The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction.	got7fsn_ti	increased force of heart contraction by circulating adrenaline|increased force of heart contraction by epinephrine in the bloodstream|positive regulation of heart contraction by circulating epinephrine|positive regulation of heart contraction by circulating adrenaline													biological_process											owl:Class	
GO:0008994	biolink:NamedThing	rhamnulose-1-phosphate aldolase activity	Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.	got7fsn_ti	L-rhamnulose-phosphate aldolase activity|rhamnulose phosphate aldolase activity|L-rhamnulose-1-phosphate lactaldehyde-lyase activity|L-rhamnulose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)|L-rhamnulose 1-phosphate aldolase activity											MetaCyc:RHAMNULPALDOL-RXN|RHEA:19689|EC:4.1.2.19		molecular_function											owl:Class	
GO:0005151	biolink:NamedThing	interleukin-1, type II receptor binding	Binding to a Type II interleukin-1 receptor.	got7fsn_ti	interleukin-1, type II receptor ligand|IL-1 type II													molecular_function											owl:Class	
GO:0005149	biolink:NamedThing	interleukin-1 receptor binding	Binding to an interleukin-1 receptor.	got7fsn_ti	IL-1|interleukin-1 receptor ligand													molecular_function											owl:Class	
GO:0002328	biolink:NamedThing	pro-B cell differentiation	The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.	got7fsn_ti	pro-B lymphocyte differentiation|pro-B cell development													biological_process											owl:Class	
GO:0002320	biolink:NamedThing	lymphoid progenitor cell differentiation	The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.	got7fsn_ti														biological_process											owl:Class	
GO:0097240	biolink:NamedThing	chromosome attachment to the nuclear envelope	The process in which chromatin is anchored to the nuclear envelope.	got7fsn_ti	attachment of chromatin to nuclear envelope						pr	2012-02-07T01:11:37Z						biological_process											owl:Class	
GO:0050483	biolink:NamedThing	IMP 5'-nucleotidase activity	Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate.	got7fsn_ti	IMP-GMP specific 5'-nucleotidase activity|IMP 5' nucleotidase activity											RHEA:27718|MetaCyc:RXN-7607		molecular_function											owl:Class	
GO:0032292	biolink:NamedThing	peripheral nervous system axon ensheathment	The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.	got7fsn_ti	ensheathment of axons in peripheral nervous system													biological_process											owl:Class	
GO:0046926	biolink:NamedThing	peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine	The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine.	got7fsn_ti												RESID:AA0342		biological_process											owl:Class	
GO:0048352	biolink:NamedThing	paraxial mesoderm structural organization	The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	paraxial mesoderm structural organisation													biological_process											owl:Class	
GO:0008211	biolink:NamedThing	glucocorticoid metabolic process	The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.	got7fsn_ti	glucocorticosteroid metabolism|glucocorticosteroid metabolic process|glucocorticoid metabolism													biological_process											owl:Class	
GO:0070584	biolink:NamedThing	mitochondrion morphogenesis	The process in which the anatomical structures of a mitochondrion are generated and organized.	got7fsn_ti					Note that this term is intended for annotation of gene products involved in mitochondrial shape changes associated with development; an example is the morphogenesis of the Nebenkern during spermatogenesis.		mah	2009-04-24T10:54:19Z						biological_process											owl:Class	
GO:0097062	biolink:NamedThing	dendritic spine maintenance	The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.	got7fsn_ti							pr	2011-06-07T11:29:03Z						biological_process											owl:Class	
GO:0036069	biolink:NamedThing	light-dependent bacteriochlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.	got7fsn_ti	light-dependent bacteriochlorophyll formation|light-dependent bacteriochlorophyll anabolism|light-dependent bacteriochlorophyll synthesis|light dependent bacteriochlorophyll biosynthetic process|light-dependent bacteriochlorophyll biosynthesis						bf	2011-12-15T04:45:16Z						biological_process											owl:Class	
GO:0030494	biolink:NamedThing	bacteriochlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.	got7fsn_ti	bacteriochlorophyll biosynthesis|bacteriochlorophyll anabolism|bacteriochlorophyll formation|bacteriochlorophyll synthesis													biological_process											owl:Class	
GO:0032603	biolink:NamedThing	fractalkine production	The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	fractalkine biosynthetic process|CX3CL1 production|neurotactin production|fractalkine metabolic process|ABCD-3 production	https://github.com/geneontology/go-ontology/issues/19254									GO:0050754|GO:0050756|GO:0050751			biological_process											owl:Class	
GO:0018123	biolink:NamedThing	peptidyl-cysteine ADP-ribosylation	The transfer, from NAD, of ADP-ribose to peptidyl-cysteine to form peptidyl-S-(ADP-ribosyl)-L-cysteine.	got7fsn_ti												RESID:AA0169		biological_process											owl:Class	
GO:0034825	biolink:NamedThing	tetralin ring-hydroxylating dioxygenase activity	Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.	got7fsn_ti												UM-BBD_reactionID:r1169|EC:1.14.12.-		molecular_function											owl:Class	
GO:0047309	biolink:NamedThing	dihydroxyphenylalanine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate.	got7fsn_ti	aspartate-DOPP transaminase (ADT)|3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase activity|DOPA aminotransferase activity|dopa transaminase activity|L-dopa transaminase activity|dihydroxyphenylalanine aminotransferase activity|phenylalanine-DOPP transaminase (PDT)|glutamate-DOPP transaminase (GDT)											EC:2.6.1.49|RHEA:15273|MetaCyc:2.6.1.49-RXN|KEGG_REACTION:R02077		molecular_function											owl:Class	
GO:0097443	biolink:NamedThing	sorting endosome	A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles.	got7fsn_ti	MVB-tubule complex						pr	2012-12-06T14:04:14Z				NIF_Subcellular:sao1028571114		cellular_component											owl:Class	
GO:0140480	biolink:NamedThing	mitotic spindle pole body insertion into the nuclear envelope	A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane.	got7fsn_ti	establishment of spindle pole body localisation in nuclear envelope|establishment of spindle pole body localization in nuclear envelope|establishment of spindle pole body localization to nuclear envelope	https://github.com/geneontology/go-ontology/issues/14887					pg	2020-06-25T14:45:40Z						biological_process											owl:Class	
GO:0070631	biolink:NamedThing	spindle pole body localization	Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.	got7fsn_ti	spindle pole body localisation|maintenance of spindle pole body localization	https://github.com/geneontology/go-ontology/issues/19149					mah	2009-05-06T02:21:38Z			GO:0071790|GO:1990944			biological_process											owl:Class	
GO:0071076	biolink:NamedThing	RNA 3' uridylation	The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.	got7fsn_ti							mah	2009-11-06T02:41:23Z						biological_process											owl:Class	
GO:0004777	biolink:NamedThing	succinate-semialdehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.	got7fsn_ti	succinate-semialdehyde dehydrogenase activity|succinyl semialdehyde dehydrogenase activity|succinic semialdehyde dehydrogenase activity|succinate semialdehyde:NAD+ oxidoreductase activity|succinate-semialdehyde:NAD+ oxidoreductase activity|succinate semialdehyde dehydrogenase activity										GO:0008952	EC:1.2.1.24|MetaCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|RHEA:13217|Reactome:R-HSA-888548		molecular_function											owl:Class	
GO:0009013	biolink:NamedThing	succinate-semialdehyde dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.	got7fsn_ti	succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate))|succinate-semialdehyde:NAD(P)+ oxidoreductase activity											MetaCyc:SUCCSEMIALDDEHYDROG-RXN|UM-BBD_reactionID:r0371|EC:1.2.1.16		molecular_function											owl:Class	
GO:0061929	biolink:NamedThing	gamma-glutamylaminecyclotransferase activity	Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline.	got7fsn_ti							dph	2017-08-29T14:57:39Z				EC:4.3.2.8|RHEA:16961		molecular_function											owl:Class	
GO:0021902	biolink:NamedThing	commitment of neuronal cell to specific neuron type in forebrain	The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0002352	biolink:NamedThing	B cell negative selection	Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.	got7fsn_ti	B lymphocyte negative selection|B-lymphocyte negative selection|B-cell negative selection													biological_process											owl:Class	
GO:0033115	biolink:NamedThing	cyanelle thylakoid membrane	The lipid bilayer membrane of any thylakoid within a cyanelle.	got7fsn_ti														cellular_component											owl:Class	
GO:0004332	biolink:NamedThing	fructose-bisphosphate aldolase activity	Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.	got7fsn_ti	ketose 1-phosphate aldolase activity|fructose diphosphate aldolase activity|fructose 1,6-diphosphate aldolase activity|D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity|SMALDO|fructose 1-monophosphate aldolase activity|phosphofructoaldolase activity|1,6-diphosphofructose aldolase activity|fructose-1,6-bisphosphate triosephosphate-lyase activity|D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)|aldolase activity|zymohexase activity|diphosphofructose aldolase activity|fructoaldolase activity|fructose 1-phosphate aldolase activity											Reactome:R-HSA-71496|MetaCyc:F16ALDOLASE-RXN|Reactome:R-HSA-71495|EC:4.1.2.13|RHEA:14729		molecular_function											owl:Class	
GO:0034209	biolink:NamedThing	sterol acetylation	The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti														biological_process											owl:Class	
GO:0018711	biolink:NamedThing	benzoyl acetate-CoA thiolase activity	Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0243|MetaCyc:RXN-1305		molecular_function											owl:Class	
GO:0035695	biolink:NamedThing	mitophagy by induced vacuole formation	The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.	got7fsn_ti	MIV-mediated mitophagy				In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.		bf	2011-02-28T03:01:04Z						biological_process											owl:Class	
GO:0039685	biolink:NamedThing	rolling hairpin viral DNA replication	A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.	got7fsn_ti	ssDNA rolling hairpin viral DNA replication						bf	2013-10-17T14:33:55Z				VZ:2656		biological_process											owl:Class	
GO:0102601	biolink:NamedThing	cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity	Catalysis of the reaction: beta-amyrin + O2 + H+ + NADPH = 16beta-hydroxy-beta-amyrin + H2O + NADP.	got7fsn_ti												RHEA:55440|EC:1.14.14.63|MetaCyc:RXN-15385		molecular_function											owl:Class	
GO:0019528	biolink:NamedThing	D-arabitol catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.	got7fsn_ti	D-arabitol degradation to xylulose 5-phosphate|D-arabitol utilization|D-arabitol degradation|D-arabitol breakdown to xylulose 5-phosphate											MetaCyc:DARABITOLUTIL-PWY		biological_process											owl:Class	
GO:0050263	biolink:NamedThing	ribosylpyrimidine nucleosidase activity	Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.	got7fsn_ti	N-ribosylpyrimidine ribohydrolase activity|nucleoside ribohydrolase activity|N-ribosylpyrimidine nucleosidase activity|YeiK|pyrimidine-nucleoside ribohydrolase activity|pyrimidine nucleosidase activity|RihB											RHEA:56816|MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN|EC:3.2.2.8		molecular_function											owl:Class	
GO:0002751	biolink:NamedThing	antigen processing and presentation following receptor mediated endocytosis	Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0002745	biolink:NamedThing	antigen processing and presentation initiated by receptor mediated uptake of antigen	Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.	got7fsn_ti														biological_process											owl:Class	
GO:0045116	biolink:NamedThing	protein neddylation	Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.	got7fsn_ti	RUB1-protein conjugation				Note that currently, the only known substrates of neddylation are cullin family proteins.						GO:0019943			biological_process											owl:Class	
GO:0007625	biolink:NamedThing	grooming behavior	The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.	got7fsn_ti	grooming behaviour													biological_process											owl:Class	
GO:0050736	biolink:NamedThing	O-malonyltransferase activity	Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0102069	biolink:NamedThing	zerumbone synthase activity	Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+.	got7fsn_ti												MetaCyc:RXN-10629|EC:1.1.1.326|RHEA:32327		molecular_function											owl:Class	
GO:0043257	biolink:NamedThing	laminin-8 complex	A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains.	got7fsn_ti	laminin-411 complex													cellular_component											owl:Class	
GO:0043755	biolink:NamedThing	alpha-ribazole phosphatase activity	Catalysis of the reaction: alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate.	got7fsn_ti	alpha-ribazole-5'-P phosphatase activity|CobC|alpha-ribazole-5'-phosphate phosphohydrolase activity										GO:0019175	MetaCyc:RIBAZOLEPHOSPHAT-RXN|KEGG_REACTION:R04594|RHEA:24456|EC:3.1.3.73		molecular_function											owl:Class	
GO:0004166	biolink:NamedThing	dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.	got7fsn_ti	dolichyl phosphate acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase activity|dolichyl-phosphate N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase activity|dolichyl phosphate N-acetylglucosaminyltransferase activity|dolichyl-phosphate acetylglucosaminyltransferase activity										GO:0004101	RHEA:14693|EC:2.4.1.153|MetaCyc:2.4.1.153-RXN		molecular_function											owl:Class	
GO:0061707	biolink:NamedThing	extracellular exosome macropinocytosis	The single-organism macropinocytosis process that results in the uptake of an extracellular exosome.	got7fsn_ti							dph	2015-06-15T16:02:38Z						biological_process											owl:Class	
GO:0044351	biolink:NamedThing	macropinocytosis	An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.	got7fsn_ti	single-organism macropinocytosis|clathrin-independent pinocytosis						jl	2011-08-11T10:26:42Z			GO:1902538			biological_process											owl:Class	
GO:0075187	biolink:NamedThing	hyphopodium formation	The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	hyphopodium formation on or near host													biological_process											owl:Class	
GO:0004648	biolink:NamedThing	O-phospho-L-serine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.	got7fsn_ti	phosphoserine aminotransferase activity|hydroxypyruvic phosphate--glutamic transaminase activity|3-phosphoserine aminotransferase activity|L-phosphoserine aminotransferase activity|3PHP transaminase activity|PSAT activity|phosphohydroxypyruvic--glutamic transaminase activity|3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity|phosphoserine transaminase activity|PdxC|SerC|phosphohydroxypyruvate transaminase activity										GO:0004646	RHEA:14329|MetaCyc:PSERTRANSAM-RXN|Reactome:R-HSA-977333|EC:2.6.1.52		molecular_function											owl:Class	
GO:0046869	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide	The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato diiron disulphide											RESID:AA0331		biological_process											owl:Class	
GO:0009001	biolink:NamedThing	serine O-acetyltransferase activity	Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA.	got7fsn_ti	acetyl-CoA:L-serine O-acetyltransferase activity|SATase activity|serine acetyltransferase activity|serine transacetylase activity|L-serine acetyltransferase activity											KEGG_REACTION:R00586|MetaCyc:SERINE-O-ACETTRAN-RXN|RHEA:24560|EC:2.3.1.30		molecular_function											owl:Class	
GO:0016412	biolink:NamedThing	serine O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule.	got7fsn_ti												EC:2.3.1.30		molecular_function											owl:Class	
GO:0021519	biolink:NamedThing	spinal cord association neuron specification	The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.	got7fsn_ti														biological_process											owl:Class	
GO:0097431	biolink:NamedThing	mitotic spindle pole	Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	got7fsn_ti							pr	2012-11-20T09:03:16Z						cellular_component											owl:Class	
GO:0036007	biolink:NamedThing	scintillon	A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen.	got7fsn_ti							bf	2011-09-21T03:04:02Z						cellular_component											owl:Class	
GO:0047909	biolink:NamedThing	galactolipid O-acyltransferase activity	Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol.	got7fsn_ti	mono-beta-D-galactosyldiacylglycerol:mono-beta-D-galactosyldiacylglycerol acyltransferase activity|galactolipid:galactolipid acyltransferase activity											MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN|EC:2.3.1.134		molecular_function											owl:Class	
GO:0031176	biolink:NamedThing	endo-1,4-beta-xylanase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.	got7fsn_ti	endo-(1->4)-beta-xylanase(1->4)-beta-xylan 4-xylanohydrolase activity|endo-beta-1,4-xylanase activity|beta-D-xylanase activity|beta-1,4-xylanase activity|endo-1,4-beta-D-xylanase activity|beta-1,4-xylan xylanohydrolase activity|1,4-beta-xylan xylanohydrolase activity|xylanase|beta-xylanase activity|endo-1,4-xylanase activity|1,4-beta-D-xylan xylanohydrolase activity|endo-(1,4)-beta-xylanase(1,4)-beta-xylan 4-xylanohydrolase activity											EC:3.2.1.8|MetaCyc:3.2.1.8-RXN		molecular_function											owl:Class	
GO:0035717	biolink:NamedThing	chemokine (C-C motif) ligand 7 binding	Binding to chemokine (C-C motif) ligand 7.	got7fsn_ti	CCL7 binding						bf	2011-03-03T04:25:41Z						molecular_function											owl:Class	
GO:0036469	biolink:NamedThing	L-tryptophan decarboxylase activity	Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine.	got7fsn_ti	L-tryptophan decarboxylase activity						bf	2014-07-21T09:22:24Z				EC:4.1.1.105|RHEA:30339		molecular_function											owl:Class	
GO:0018482	biolink:NamedThing	4-formylbenzenesulfonate dehydrogenase activity	Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH.	got7fsn_ti	toluene-sulfonate aldehyde dehydrogenase activity|4-formylbenzenesulfonate:NAD+ oxidoreductase activity|4-formylbenzenesulphonate dehydrogenase activity											RHEA:18833|MetaCyc:1.2.1.62-RXN|EC:1.2.1.62|UM-BBD_reactionID:r0292|KEGG_REACTION:R05272		molecular_function											owl:Class	
GO:0018187	biolink:NamedThing	molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide	The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide.	got7fsn_ti												RESID:AA0281		biological_process											owl:Class	
GO:0036401	biolink:NamedThing	pyrokinin receptor activity	Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation.	got7fsn_ti	PK receptor activity						bf	2013-07-18T15:10:55Z						molecular_function											owl:Class	
GO:1990443	biolink:NamedThing	peptidyl-threonine autophosphorylation	The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.	got7fsn_ti							al	2014-08-02T15:08:41Z						biological_process											owl:Class	
GO:0102148	biolink:NamedThing	N-acetyl-beta-D-galactosaminidase activity	Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan.	got7fsn_ti												EC:3.2.1.52|MetaCyc:RXN-11622		molecular_function											owl:Class	
GO:0031258	biolink:NamedThing	lamellipodium membrane	The portion of the plasma membrane surrounding a lamellipodium.	got7fsn_ti														cellular_component											owl:Class	
GO:0000977	biolink:NamedThing	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.	got7fsn_ti	RNA polymerase II regulatory region DNA binding	https://github.com/geneontology/go-ontology/issues/19312			To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2010-08-10T11:05:36Z			GO:0001012			molecular_function											owl:Class	
GO:0042272	biolink:NamedThing	nuclear RNA export factor complex	A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm.	got7fsn_ti	Mex67-Mtr2 complex|TAP-p15 complex|NXF1-NXT1 complex													cellular_component											owl:Class	
GO:0005359	biolink:NamedThing	low-affinity glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	got7fsn_ti	low-affinity hydrogen/glucose transporter activity|low-affinity hydrogen:glucose transporter activity|low-affinity hydrogen:glucose symporter activity													molecular_function											owl:Class	
GO:0048491	biolink:NamedThing	retrograde synaptic vesicle transport	The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body.	got7fsn_ti	retrograde axonal transport of synaptic vesicle													biological_process											owl:Class	
GO:0034750	biolink:NamedThing	Scrib-APC-beta-catenin complex	A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation.	got7fsn_ti	hScrib-APC-beta-catenin complex				Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0019885	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class I|antigen processing, endogenous antigen via MHC class I|antigen processing, endogenous antigen via major histocompatibility complex class I|antigen presentation, endogenous peptide antigen										GO:0048004			biological_process											owl:Class	
GO:0050929	biolink:NamedThing	induction of negative chemotaxis	Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.	got7fsn_ti														biological_process											owl:Class	
GO:0050924	biolink:NamedThing	positive regulation of negative chemotaxis	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.	got7fsn_ti	stimulation of negative chemotaxis|up regulation of negative chemotaxis|upregulation of negative chemotaxis|activation of negative chemotaxis|up-regulation of negative chemotaxis													biological_process											owl:Class	
GO:0010427	biolink:NamedThing	abscisic acid binding	Binding to abscisic acid, a plant hormone that regulates aspects of plant growth.	got7fsn_ti	abscisate binding|ABA binding													molecular_function											owl:Class	
GO:0016840	biolink:NamedThing	carbon-nitrogen lyase activity	Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).	got7fsn_ti	other carbon-nitrogen lyase activity											EC:4.3.-.-		molecular_function											owl:Class	
GO:0052543	biolink:NamedThing	callose deposition in cell wall	Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	got7fsn_ti	cell wall callose deposition|callose localization in cell wall|cell wall callose localization													biological_process											owl:Class	
GO:0045295	biolink:NamedThing	gamma-catenin binding	Binding to catenin complex gamma subunit.	got7fsn_ti	plakoglobin binding													molecular_function											owl:Class	
GO:0044598	biolink:NamedThing	doxorubicin metabolic process	The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy.	got7fsn_ti							jl	2012-05-01T03:30:21Z						biological_process											owl:Class	
GO:0016137	biolink:NamedThing	glycoside metabolic process	The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.	got7fsn_ti	O-glycoside metabolism|O-glycoside metabolic process|glycoside metabolism										GO:0016140			biological_process											owl:Class	
GO:0036510	biolink:NamedThing	trimming of terminal mannose on C branch	The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.	got7fsn_ti	conversion of (Man)9(GlcNAc)2 to (Man)8C(GlcNAc)2|conversion of M9 to M8C|glycoprotein mannose trimming on C branch				Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T14:10:52Z						biological_process											owl:Class	
GO:0032411	biolink:NamedThing	positive regulation of transporter activity	Any process that activates or increases the activity of a transporter.	got7fsn_ti	activation of transporter activity|up regulation of transporter activity|upregulation of transporter activity|up-regulation of transporter activity|stimulation of transporter activity													biological_process											owl:Class	
GO:0050672	biolink:NamedThing	negative regulation of lymphocyte proliferation	Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.	got7fsn_ti	inhibition of lymphocyte proliferation|down regulation of lymphocyte proliferation|down-regulation of lymphocyte proliferation|downregulation of lymphocyte proliferation													biological_process											owl:Class	
GO:0008741	biolink:NamedThing	ribulokinase activity	Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.	got7fsn_ti	L-ribulokinase activity|ribulokinase (phosphorylating)|ATP:L(or D)-ribulose 5-phosphotransferase activity											EC:2.7.1.16|MetaCyc:RIBULOKIN-RXN|RHEA:22072		molecular_function											owl:Class	
GO:0050323	biolink:NamedThing	taurine dehydrogenase activity	Catalysis of the reaction: A + H(2)O + taurine = AH(2) + NH(4)(+) + sulfoacetaldehyde.	got7fsn_ti	taurine:acceptor oxidoreductase (deaminating)|taurine:(acceptor) oxidoreductase (deaminating)											MetaCyc:TAURINE-DEHYDROGENASE-RXN|KEGG_REACTION:R07167|EC:1.4.99.2|RHEA:18709		molecular_function											owl:Class	
GO:0003432	biolink:NamedThing	cell growth involved in growth plate cartilage chondrocyte morphogenesis	The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time.	got7fsn_ti							dph	2009-12-22T12:37:48Z						biological_process											owl:Class	
GO:0042659	biolink:NamedThing	regulation of cell fate specification	Any process that mediates the adoption of a specific fate by a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0061635	biolink:NamedThing	regulation of protein complex stability	Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly.	got7fsn_ti							dph	2014-08-13T14:40:21Z						biological_process											owl:Class	
GO:0005767	biolink:NamedThing	secondary lysosome	Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome.	got7fsn_ti												NIF_Subcellular:sao1549842807		cellular_component											owl:Class	
GO:1990699	biolink:NamedThing	palmitoleyl hydrolase activity	Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate.	got7fsn_ti							sp	2015-03-13T09:00:05Z						molecular_function											owl:Class	
GO:0051318	biolink:NamedThing	G1 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:G1_phase		biological_process											owl:Class	
GO:0016005	biolink:NamedThing	phospholipase A2 activator activity	Increases the activity of the enzyme phospholipase A2.	got7fsn_ti														molecular_function											owl:Class	
GO:0021616	biolink:NamedThing	glossopharyngeal nerve formation	The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	got7fsn_ti	CN IX formation|CN IX biosynthesis													biological_process											owl:Class	
GO:0090486	biolink:NamedThing	small RNA 2'-O-methyltransferase	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA <=> S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide.	got7fsn_ti							tb	2012-10-15T16:32:49Z						molecular_function											owl:Class	
GO:0036159	biolink:NamedThing	inner dynein arm assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.	got7fsn_ti	IDA assembly						bf	2012-03-21T02:25:01Z						biological_process											owl:Class	
GO:0070286	biolink:NamedThing	axonemal dynein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.	got7fsn_ti	dynein arm assembly													biological_process											owl:Class	
GO:0045278	biolink:NamedThing	plasma membrane respiratory chain complex IV	A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species.	got7fsn_ti	respiratory chain complex IV|cytochrome c oxidase complex										GO:0045288			cellular_component											owl:Class	
GO:0030622	biolink:NamedThing	U4atac snRNA binding	Binding to a U4atac small nuclear RNA (U4atac snRNA).	got7fsn_ti														molecular_function											owl:Class	
GO:0075294	biolink:NamedThing	positive regulation by symbiont of entry into host	Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	up regulation by organism of entry into other organism during symbiotic interaction|positive regulation by organism of entry into other organism involved in symbiotic interaction|up regulation by symbiont of entry into host|positive regulation by organism of entry into other organism during symbiotic interaction|up-regulation by organism of entry into other organism during symbiotic interaction|activation by symbiont of entry into host|upregulation by organism of entry into other organism during symbiotic interaction|up-regulation by symbiont of entry into host|upregulation by symbiont of entry into host|activation by organism of entry into other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/19027									GO:0075295			biological_process											owl:Class	
GO:0035629	biolink:NamedThing	N-terminal protein amino acid N-linked glycosylation	Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein.	got7fsn_ti					Note that the only known alpha amino glycosylation is on an asparagine; see UniProtKB:P58522. However, this feature is not differentiated from normal N-glycosylation of asparagine.		bf	2010-12-17T10:45:48Z						biological_process											owl:Class	
GO:0060746	biolink:NamedThing	parental behavior	A reproductive behavior in which a parent cares for and rears offspring.	got7fsn_ti							dph	2009-06-22T09:05:26Z						biological_process											owl:Class	
GO:0009943	biolink:NamedThing	adaxial/abaxial axis specification	The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.	got7fsn_ti	adaxial/abaxial determination													biological_process											owl:Class	
GO:0044721	biolink:NamedThing	protein import into peroxisome matrix, substrate release	The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane.	got7fsn_ti							jl	2012-10-18T14:07:40Z						biological_process											owl:Class	
GO:0097726	biolink:NamedThing	LEM domain binding	Binding to a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF).	got7fsn_ti	LAP2, emerin, MAN1 domain binding|lamina-associated polypeptide, emerin, MAN1 domain binding						pr	2016-09-19T10:19:02Z						molecular_function											owl:Class	
GO:0001957	biolink:NamedThing	intramembranous ossification	Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.	got7fsn_ti	dermal ossification|intramembranous bone ossification				An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.							Wikipedia:Intramembranous_ossification		biological_process											owl:Class	
GO:0005460	biolink:NamedThing	UDP-glucose transmembrane transporter activity	Enables the transfer of a UDP-glucose from one side of a membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0006560	biolink:NamedThing	proline metabolic process	The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.	got7fsn_ti	proline metabolism													biological_process											owl:Class	
GO:0097530	biolink:NamedThing	granulocyte migration	The movement of a granulocyte within or between different tissues and organs of the body.	got7fsn_ti							pr	2013-11-11T14:00:44Z						biological_process											owl:Class	
GO:0047134	biolink:NamedThing	protein-disulfide reductase (NAD(P)) activity	Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.	got7fsn_ti	insulin-glutathione transhydrogenase activity|NAD(P)H:protein-disulfide oxidoreductase activity|protein-disulfide reductase activity|protein disulphide reductase activity|disulfide reductase activity|protein disulfide reductase (NAD(P)H) activity|protein-disulphide reductase activity|protein disulfide reductase activity	https://github.com/geneontology/go-ontology/issues/20219										MetaCyc:1.6.4.4-RXN|EC:1.8.1.8		molecular_function											owl:Class	
GO:0052020	biolink:NamedThing	modification by symbiont of host cell wall	The process in which an organism effects a change in the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	metabolism of host cell wall by organism													biological_process											owl:Class	
GO:0052333	biolink:NamedThing	modification by organism of cell wall of other organism involved in symbiotic interaction	The process in which an organism effects a change in the structure or function of the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism by organism of cell wall of other organism|modification by organism of cell wall of other organism during symbiotic interaction													biological_process											owl:Class	
GO:0031844	biolink:NamedThing	type 4 neuropeptide Y receptor binding	Binding to a type 4 neuropeptide Y receptor.	got7fsn_ti	pancreatic polypeptide receptor binding|type 4 neuropeptide Y receptor ligand													molecular_function											owl:Class	
GO:0031841	biolink:NamedThing	neuropeptide Y receptor binding	Binding to a neuropeptide Y receptor.	got7fsn_ti	neuropeptide Y receptor ligand|NPY receptor binding													molecular_function											owl:Class	
GO:0018620	biolink:NamedThing	phthalate 4,5-dioxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+).	got7fsn_ti	PDO activity|phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating)|phthalate dioxygenase activity											EC:1.14.12.7|UM-BBD_reactionID:r0102|KEGG_REACTION:R03630|RHEA:17489|MetaCyc:PHTHALATE-45-DIOXYGENASE-RXN		molecular_function											owl:Class	
GO:0061422	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH >7.0.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter in response to alkalinity						dph	2012-01-26T12:42:21Z						biological_process											owl:Class	
GO:0071469	biolink:NamedThing	cellular response to alkaline pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti	cellular response to basic pH|cellular response to alkalinity						mah	2009-12-18T11:42:47Z						biological_process											owl:Class	
GO:0032148	biolink:NamedThing	activation of protein kinase B activity	Any process that initiates the activity of the inactive enzyme protein kinase B.	got7fsn_ti	protein kinase B activation													biological_process											owl:Class	
GO:1990636	biolink:NamedThing	reproductive senescence	A natural reduction in reproductive capacity with aging, often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones.	got7fsn_ti							sl	2015-02-10T23:17:56Z						biological_process											owl:Class	
GO:0031426	biolink:NamedThing	polycistronic mRNA processing	The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0006813	biolink:NamedThing	potassium ion transport	The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	potassium ion conductance|cellular potassium ion transport|low voltage-dependent potassium channel auxiliary protein activity|low voltage-gated potassium channel auxiliary protein activity|potassium conductance|sodium/potassium transport|potassium transport|K+ conductance						mah	2010-09-03T02:39:22Z			GO:0071804|GO:0015458			biological_process											owl:Class	
GO:0016473	biolink:NamedThing	sodium ion-transporting F-type ATPase complex	A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism.	got7fsn_ti	sodium-translocating F-type ATPase complex													cellular_component											owl:Class	
GO:0004736	biolink:NamedThing	pyruvate carboxylase activity	Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H(+) + oxaloacetate + phosphate.	got7fsn_ti	pyruvate:carbon-dioxide ligase (ADP-forming)|pyruvic carboxylase activity											EC:6.4.1.1|MetaCyc:PYRUVATE-CARBOXYLASE-RXN|KEGG_REACTION:R00344|RHEA:20844|Reactome:R-HSA-70501		molecular_function											owl:Class	
GO:0050128	biolink:NamedThing	N-feruloylglycine deacylase activity	Catalysis of the reaction: N-feruloylglycine + H(2)O = ferulate + glycine.	got7fsn_ti	N-feruloylglycine amidohydrolase activity|N-feruloylglycine hydrolase activity											EC:3.5.1.71|KEGG_REACTION:R03579|MetaCyc:N-FERULOYLGLYCINE-DEACYLASE-RXN|RHEA:10484		molecular_function											owl:Class	
GO:0060344	biolink:NamedThing	liver trabecula formation	The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.	got7fsn_ti	liver trabecula biogenesis|liver trabeculation													biological_process											owl:Class	
GO:0014855	biolink:NamedThing	striated muscle cell proliferation	The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.	got7fsn_ti														biological_process											owl:Class	
GO:0033002	biolink:NamedThing	muscle cell proliferation	The expansion of a muscle cell population by cell division.	got7fsn_ti	myocyte proliferation													biological_process											owl:Class	
GO:0097402	biolink:NamedThing	neuroblast migration	The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.	got7fsn_ti							pr	2012-10-29T08:24:37Z						biological_process											owl:Class	
GO:0014064	biolink:NamedThing	positive regulation of serotonin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.	got7fsn_ti	positive regulation of serotonin release|up-regulation of serotonin secretion|stimulation of serotonin secretion|up regulation of serotonin secretion|upregulation of serotonin secretion|activation of serotonin secretion													biological_process											owl:Class	
GO:0003390	biolink:NamedThing	dendrite development by retrograde extension	The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point.	got7fsn_ti	dendrite retrograde extension						dph	2009-12-09T09:25:24Z						biological_process											owl:Class	
GO:0034611	biolink:NamedThing	oligoribonucleotidase activity	Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates.	got7fsn_ti	RNA oligonucleotidase activity											Reactome:R-HSA-9009950|Reactome:R-HSA-9615042		molecular_function											owl:Class	
GO:0008946	biolink:NamedThing	oligonucleotidase activity	Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates.	got7fsn_ti					Note that enzymes with this activity usually also hydrolyze NAD+ to NMN and AMP.							EC:3.1.13.3|MetaCyc:3.1.13.3-RXN		molecular_function											owl:Class	
GO:0018643	biolink:NamedThing	carbon disulfide oxygenase activity	Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide.	got7fsn_ti	carbon disulphide oxygenase activity											EC:1.14.13.-|UM-BBD_reactionID:r0599		molecular_function											owl:Class	
GO:0033445	biolink:NamedThing	AGU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AGU codon.	got7fsn_ti	AGT codon-amino acid adaptor activity|serine tRNA				Note that in the standard genetic code, AGT codes for serine.									molecular_function											owl:Class	
GO:0003317	biolink:NamedThing	cardioblast cell midline fusion	The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment.	got7fsn_ti	cardiac progenitor cell midline fusion						dph	2009-10-27T09:08:57Z						biological_process											owl:Class	
GO:0034109	biolink:NamedThing	homotypic cell-cell adhesion	The attachment of a cell to a second cell of the identical type via adhesion molecules.	got7fsn_ti					Note that this term is not synonymous with 'homophilic cell adhesion ; GO:0007156'; the process may occur by homophilic or heterophilic mechanisms.									biological_process											owl:Class	
GO:0043777	biolink:NamedThing	cobalt-precorrin-7 C15-methyltransferase activity	Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2.	got7fsn_ti	precorrin-6Y methylase|cobalt-precorrin 7 C15-methyltransferase activity|precorrin-6 methyltransferase|precorrin-6Y C5,15-methyltransferase (decarboxylating)											RHEA:34591|MetaCyc:RXN-8767		molecular_function											owl:Class	
GO:0097081	biolink:NamedThing	vascular associated smooth muscle cell fate commitment	The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	got7fsn_ti	vascular smooth muscle cell fate commitment						pr	2011-06-20T03:51:52Z						biological_process											owl:Class	
GO:0035579	biolink:NamedThing	specific granule membrane	The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.	got7fsn_ti	secondary granule membrane						bf	2010-10-05T01:32:47Z						cellular_component											owl:Class	
GO:0047111	biolink:NamedThing	formate dehydrogenase (cytochrome-c-553) activity	Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2.	got7fsn_ti	formate dehydrogenase (cytochrome c-553)|formate:ferricytochrome-c-553 oxidoreductase activity											RHEA:15189|MetaCyc:1.2.2.3-RXN|EC:1.17.2.3		molecular_function											owl:Class	
GO:0140164	biolink:NamedThing	Golgi transport complex binding	Binding to a Golgi transport complex, a multisubunit tethering complex of the CATCHR family.	got7fsn_ti	COG complex binding						pg	2018-02-08T11:49:38Z						molecular_function											owl:Class	
GO:0102853	biolink:NamedThing	1-18:1-2-18:1-sn-glycerol-3-phosphocholine desaturase activity	Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8320		molecular_function											owl:Class	
GO:0005138	biolink:NamedThing	interleukin-6 receptor binding	Binding to an interleukin-6 receptor.	got7fsn_ti	IL-6|interleukin-6 receptor ligand													molecular_function											owl:Class	
GO:0017103	biolink:NamedThing	UTP:galactose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose.	got7fsn_ti	UTP-hexose-1-phosphate uridylyltransferase activity|galactose 1-phosphate uridyltransferase activity|galactose 1-phosphate uridylyltransferase activity|UTP:alpha-D-hexose-1-phosphate uridylyltransferase activity|galactose-1-phosphate uridylyltransferase activity|uridine diphosphogalactose pyrophosphorylase activity|uridine diphosphate galactose pyrophosphorylase activity|UTP:hexose-1-phosphate uridylyltransferase activity|Gal-1-P uridylyltransferase activity|UDPgalactose pyrophosphorylase activity|alpha-D-galactose 1-phosphate uridylyltransferase activity										GO:0003982	RHEA:14209|KEGG_REACTION:R00502|EC:2.7.7.10|MetaCyc:UTPHEXPURIDYLYLTRANS-RXN		molecular_function											owl:Class	
GO:0016797	biolink:NamedThing	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.	got7fsn_ti					Note that this activity can catalyze cleavage of DNA or RNA.							EC:3.1.16.-		molecular_function											owl:Class	
GO:0033474	biolink:NamedThing	indoleacetic acid conjugate biosynthetic process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.	got7fsn_ti	indoleacetic acid conjugate biosynthesis|indoleacetic acid conjugate anabolism|indole acetic acid conjugate biosynthesis|indole acetic acid conjugate biosynthetic process|indoleacetic acid conjugate synthesis|indoleacetic acid conjugate formation|IAA conjugate biosynthetic process													biological_process											owl:Class	
GO:0016741	biolink:NamedThing	transferase activity, transferring one-carbon groups	Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).	got7fsn_ti	methyltransferase activity	https://github.com/geneontology/go-ontology/issues/20486										EC:2.1.-.-		molecular_function											owl:Class	
GO:0030633	biolink:NamedThing	D-alanine family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of D-alanine and related amino acids.	got7fsn_ti	D-alanine family amino acid catabolism|D-alanine family amino acid degradation|D-alanine family amino acid breakdown													biological_process											owl:Class	
GO:2000947	biolink:NamedThing	positive regulation of amylopectin catabolic process	Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process.	got7fsn_ti	positive regulation of Amylopectin catabolism						tt	2011-08-01T02:15:32Z						biological_process											owl:Class	
GO:2000883	biolink:NamedThing	positive regulation of starch catabolic process	Any process that activates or increases the frequency, rate or extent of starch catabolic process.	got7fsn_ti	positive regulation of starch breakdown|positive regulation of starch degradation|positive regulation of starch catabolism						bf	2011-07-27T03:23:51Z						biological_process											owl:Class	
GO:0018005	biolink:NamedThing	N-terminal peptidyl-glycine N-formylation	The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine.	got7fsn_ti												RESID:AA0057		biological_process											owl:Class	
GO:0018004	biolink:NamedThing	N-terminal protein formylation	The formylation of the N-terminal amino acid of proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0034943	biolink:NamedThing	trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity	Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.	got7fsn_ti												UM-BBD_reactionID:r0989		molecular_function											owl:Class	
GO:0047425	biolink:NamedThing	1-pyrroline-4-hydroxy-2-carboxylate deaminase activity	Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H(2)O + H(+) = 2,5-dioxopentanoate + NH(4)(+).	got7fsn_ti	HPC deaminase activity|1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing)											EC:3.5.4.22|RHEA:10560|KEGG_REACTION:R02280|MetaCyc:3.5.4.22-RXN		molecular_function											owl:Class	
GO:0010438	biolink:NamedThing	cellular response to sulfur starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur.	got7fsn_ti														biological_process											owl:Class	
GO:0089719	biolink:NamedThing	RHG protein domain binding	Binding to an RHG (reaper/hid/grimm) domain/motif (AKA iap binding motif).	got7fsn_ti	RHG domain binding|inhibitor of apoptosis binding domain binding|reaper hid grim domain binding|iap binding domain binding													molecular_function											owl:Class	
GO:1902104	biolink:NamedThing	positive regulation of metaphase/anaphase transition of meiotic cell cycle	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.	got7fsn_ti	up-regulation of metaphase/anaphase transition of meiotic cell cycle|activation of metaphase/anaphase transition of meiotic cell cycle|activation of meiotic metaphase/anaphase transition|positive regulation of meiotic metaphase/anaphase transition|upregulation of metaphase/anaphase transition of meiotic cell cycle|up-regulation of meiotic metaphase/anaphase transition|upregulation of meiotic metaphase/anaphase transition|up regulation of meiotic metaphase/anaphase transition|up regulation of metaphase/anaphase transition of meiotic cell cycle						jl	2013-05-02T12:45:48Z						biological_process											owl:Class	
GO:1905134	biolink:NamedThing	positive regulation of meiotic chromosome separation	Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation.	got7fsn_ti	activation of meiotic chromosome separation|up-regulation of chromosome separation during meiosis|upregulation of meiotic chromosome resolution|up regulation of meiotic chromosome separation|up regulation of chromosome separation during meiosis|positive regulation of meiotic chromosome resolution|upregulation of meiotic chromosome separation|positive regulation of chromosome separation during meiosis|activation of chromosome separation during meiosis|up-regulation of meiotic chromosome separation|activation of meiotic chromosome resolution|up-regulation of meiotic chromosome resolution|upregulation of chromosome separation during meiosis|up regulation of meiotic chromosome resolution						dph	2016-04-12T17:46:45Z						biological_process											owl:Class	
GO:0099630	biolink:NamedThing	postsynaptic neurotransmitter receptor cycle	The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome,  transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0099627	biolink:NamedThing	neurotransmitter receptor cycle	The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome.  This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome,  transport back the synaptic membrane and subsequent anchoring (trapping).	got7fsn_ti														biological_process											owl:Class	
GO:0061750	biolink:NamedThing	acid sphingomyelin phosphodiesterase activity	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in an acidic environment.	got7fsn_ti	acid SMase|acid sphingomyelinase						dph	2015-11-11T14:47:45Z						molecular_function											owl:Class	
GO:0036526	biolink:NamedThing	peptidyl-cysteine deglycation	The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein.	got7fsn_ti	deglycation of N-acetylcysteine						bf	2016-08-04T10:35:25Z						biological_process											owl:Class	
GO:0046826	biolink:NamedThing	negative regulation of protein export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.	got7fsn_ti	negative regulation of protein transport from nucleus to cytoplasm|downregulation of protein export from nucleus|down-regulation of protein export from nucleus|down regulation of protein export from nucleus|inhibition of protein export from nucleus|negative regulation of protein-nucleus export|negative regulation of protein export out of nucleus|negative regulation of protein export from cell nucleus													biological_process											owl:Class	
GO:0051457	biolink:NamedThing	maintenance of protein location in nucleus	Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.	got7fsn_ti	nuclear protein retention|sequestration of protein in nucleus|maintenance of protein localization in nucleus|protein retention in nucleus|protein-nuclear retention|nuclear protein sequestration|storage of protein in nucleus|nuclear protein sequestering|protein sequestration in nucleus|maintenance of nuclear protein localization|protein storage in nucleus|maintenance of protein location in cell nucleus													biological_process											owl:Class	
GO:0120195	biolink:NamedThing	positive regulation of anther dehiscence	Any process that activates or increases the frequency, rate or extent of anther dehiscence.	got7fsn_ti							krc	2019-04-09T21:58:31Z						biological_process											owl:Class	
GO:0005220	biolink:NamedThing	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	InsP3 receptor|inositol-1,4,5-trisphosphate receptor activity|IP3 receptor activity										GO:0008095			molecular_function											owl:Class	
GO:0010845	biolink:NamedThing	positive regulation of reciprocal meiotic recombination	Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti	positive regulation of meiotic recombination													biological_process											owl:Class	
GO:0031298	biolink:NamedThing	replication fork protection complex	A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling.	got7fsn_ti	replisome progression complex|Swi1-Swi3 complex|TIMELESS-TIPIN complex													cellular_component											owl:Class	
GO:0002300	biolink:NamedThing	CD8-positive, alpha-beta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	got7fsn_ti	CD8-positive, alpha-beta intraepithelial T-cell differentiation|CD8-positive, alpha-beta intraepithelial T-lymphocyte differentiation|CD8-positive, alpha-beta intraepithelial T cell development|CD8-positive, alpha-beta intraepithelial T lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0050936	biolink:NamedThing	xanthophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.	got7fsn_ti	xanthophore cell differentiation				Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure.									biological_process											owl:Class	
GO:0046841	biolink:NamedThing	trisporic acid metabolic process	The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota.	got7fsn_ti	trisporic acid metabolism													biological_process											owl:Class	
GO:0010015	biolink:NamedThing	root morphogenesis	The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support.	got7fsn_ti														biological_process											owl:Class	
GO:0047242	biolink:NamedThing	hydroxyanthraquinone glucosyltransferase activity	Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP.	got7fsn_ti	uridine diphosphoglucose-anthraquinone glucosyltransferase activity|UDP-glucose:hydroxyanthraquinone O-glucosyltransferase activity|anthraquinone-specific glucosyltransferase activity|UDPglucose:hydroxyanthraquinone O-glucosyltransferase activity											MetaCyc:2.4.1.181-RXN|EC:2.4.1.181		molecular_function											owl:Class	
GO:0021522	biolink:NamedThing	spinal cord motor neuron differentiation	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0036252	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to menadione	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter in response to menadione stress						bf	2012-06-12T11:40:58Z						biological_process											owl:Class	
GO:0098986	biolink:NamedThing	T-bar	A T-shaped presynpatic density.  These are common in arhropod central nervous systems.	got7fsn_ti														cellular_component											owl:Class	
GO:0098980	biolink:NamedThing	presynaptic density	An electron dense specialization of the presynaptic active zone cytoskeleton.	got7fsn_ti														cellular_component											owl:Class	
GO:0140640	biolink:NamedThing	catalytic activity, acting on a nucleic acid	Catalytic activity that acts to modify a nucleic acid.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21402					pg	2021-05-11T06:31:07Z						molecular_function											owl:Class	
GO:1901321	biolink:NamedThing	positive regulation of heart induction	Any process that activates or increases the frequency, rate or extent of heart induction.	got7fsn_ti	up-regulation of heart induction|upregulation of heart induction|up regulation of heart induction|activation of heart induction						bf	2012-08-28T15:49:51Z						biological_process											owl:Class	
GO:0090421	biolink:NamedThing	embryonic meristem initiation	Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.	got7fsn_ti							tb	2012-04-13T02:52:34Z						biological_process											owl:Class	
GO:0018886	biolink:NamedThing	anaerobic carbon tetrachloride metabolic process	The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen.	got7fsn_ti	anaerobic carbon tetrachloride metabolism											UM-BBD_pathwayID:ctc		biological_process											owl:Class	
GO:0018885	biolink:NamedThing	carbon tetrachloride metabolic process	The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.	got7fsn_ti	carbon tetrachloride metabolism											UM-BBD_pathwayID:ctc		biological_process											owl:Class	
GO:0030620	biolink:NamedThing	U2 snRNA binding	Binding to a U2 small nuclear RNA (U2 snRNA).	got7fsn_ti														molecular_function											owl:Class	
GO:1900052	biolink:NamedThing	regulation of retinoic acid biosynthetic process	Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process.	got7fsn_ti	regulation of retinoic acid anabolic process						yaf	2012-01-20T09:55:45Z						biological_process											owl:Class	
GO:0070002	biolink:NamedThing	glutamic-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.	got7fsn_ti														molecular_function											owl:Class	
GO:0004328	biolink:NamedThing	formamidase activity	Catalysis of the reaction: formamide + H(2)O = formate + NH(4)(+).	got7fsn_ti	formamide hydrolase activity|formamide amidohydrolase activity										GO:0034566	RHEA:21948|EC:3.5.1.49|MetaCyc:FORMAMIDASE-RXN|UM-BBD_reactionID:r0873|KEGG_REACTION:R00524		molecular_function											owl:Class	
GO:0032334	biolink:NamedThing	inhibin secretion	The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.	got7fsn_ti														biological_process											owl:Class	
GO:0070255	biolink:NamedThing	regulation of mucus secretion	Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.	got7fsn_ti	regulation of mucus production													biological_process											owl:Class	
GO:0045228	biolink:NamedThing	slime layer polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall.	got7fsn_ti	slime layer polysaccharide synthesis|slime layer polysaccharide anabolism|slime layer polysaccharide biosynthesis|slime layer polysaccharide formation													biological_process											owl:Class	
GO:0045226	biolink:NamedThing	extracellular polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures.	got7fsn_ti	extracellular polysaccharide synthesis|extracellular polysaccharide formation|extracellular polysaccharide biosynthesis|extracellular polysaccharide anabolism													biological_process											owl:Class	
GO:1990040	biolink:NamedThing	sub-surface cisterna	Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane.	got7fsn_ti	sub-surface cisternae						pr	2013-02-11T15:10:47Z				NIF_Subcellular:sao128470897		cellular_component											owl:Class	
GO:1990039	biolink:NamedThing	hypolemmal cisterna	Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer.	got7fsn_ti	hypolemmal cisternae						pr	2013-02-11T15:04:56Z				NIF_Subcellular:sao1634374950		cellular_component											owl:Class	
GO:0004938	biolink:NamedThing	alpha2-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein.	got7fsn_ti	alpha2 adrenoceptor													molecular_function											owl:Class	
GO:0004936	biolink:NamedThing	alpha-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors.	got7fsn_ti	alpha adrenoceptor													molecular_function											owl:Class	
GO:0080191	biolink:NamedThing	secondary thickening	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem.	got7fsn_ti					Occurs in shoot axes in some monocotyledons such as Dracaena, and rarely in roots of monocotyledons. Distinct from primary thickening, because it is distant from and generally discontinuous with the apical meristem.		dhl	2012-12-06T15:50:33Z						biological_process											owl:Class	
GO:0018301	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon	The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-cysteine persulphido-bis-L-glutamato-L-histidino tetrairon											RESID:AA0268		biological_process											owl:Class	
GO:1903114	biolink:NamedThing	silver ion transmembrane transporter complex	A protein complex which is capable of silver ion transmembrane transporter activity.	got7fsn_ti					An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:11283292 (inferred from direct assay).		bhm	2014-06-10T10:00:02Z						cellular_component											owl:Class	
GO:0031991	biolink:NamedThing	regulation of actomyosin contractile ring contraction	Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.	got7fsn_ti	regulation of contractile ring contraction involved in cell cycle cytokinesis|regulation of actomyosin contractile ring constriction|regulation of contractile ring contraction involved in cytokinesis during cell cycle	https://github.com/geneontology/go-ontology/issues/21855												biological_process											owl:Class	
GO:0102545	biolink:NamedThing	phosphatidyl phospholipase B activity	Catalysis of the reaction: 2 H2O + a phosphatidylcholine = sn-glycero-3-phosphocholine + 2 H+ + 2 a carboxylate.	got7fsn_ti												MetaCyc:RXN-14899|EC:3.1.1.5		molecular_function											owl:Class	
GO:0019460	biolink:NamedThing	glutamine catabolic process to fumarate	The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate.	got7fsn_ti	glutamate catabolic process to fumarate|glutamine breakdown to fumarate|glutamine degradation to fumarate													biological_process											owl:Class	
GO:1990310	biolink:NamedThing	type-III dockerin domain binding	Binding to a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain.	got7fsn_ti							tt	2014-03-07T03:22:36Z						molecular_function											owl:Class	
GO:0047772	biolink:NamedThing	carboxymethyloxysuccinate lyase activity	Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate.	got7fsn_ti	carboxymethyloxysuccinate glycolate-lyase (fumarate-forming)|carboxymethyloxysuccinate glycolate-lyase activity											MetaCyc:CARBOXYMETHYLOXYSUCCINATE-LYASE-RXN|EC:4.2.99.12|RHEA:12336|KEGG_REACTION:R01336		molecular_function											owl:Class	
GO:0031421	biolink:NamedThing	invertasome	A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts.	got7fsn_ti														cellular_component											owl:Class	
GO:0010691	biolink:NamedThing	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.	got7fsn_ti														biological_process											owl:Class	
GO:0102775	biolink:NamedThing	6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity	Catalysis of the reaction: 2 H+ + isovaleryl-CoA + 3 malonyl-CoA = 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone + 4 coenzyme A + 3 carbon dioxide.	got7fsn_ti												MetaCyc:RXN-7826		molecular_function											owl:Class	
GO:0103073	biolink:NamedThing	anandamide amidohydrolase activity	Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+).	got7fsn_ti												MetaCyc:RXN6666-2|EC:3.5.1.99|RHEA:26136		molecular_function											owl:Class	
GO:0102395	biolink:NamedThing	9-cis-beta-carotene 9',10'-cleavage oxygenase activity	Catalysis of the reaction: 9-cis-beta-carotene + O2 <=> 9-cis-10'-apo-beta-carotenal + beta-ionone.	got7fsn_ti												EC:1.13.11.68|RHEA:34399|MetaCyc:RXN-13642		molecular_function											owl:Class	
GO:0097569	biolink:NamedThing	lateral shield	Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella.	got7fsn_ti					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-11T13:37:10Z						cellular_component											owl:Class	
GO:0048874	biolink:NamedThing	host-mediated regulation of intestinal microbiota composition	The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut.	got7fsn_ti	homeostasis of number of cells in a free-living population|host-induced regulation of intestinal microbiota composition	https://github.com/geneontology/go-ontology/issues/15748												biological_process											owl:Class	
GO:0032311	biolink:NamedThing	angiogenin-PRI complex	A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.	got7fsn_ti	angiogenin-placental ribonuclease inhibitor complex													cellular_component											owl:Class	
GO:0070983	biolink:NamedThing	dendrite guidance	The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.	got7fsn_ti	dendritic guidance						mah	2009-10-27T03:53:23Z						biological_process											owl:Class	
GO:0030604	biolink:NamedThing	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH.	got7fsn_ti	2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)|1-deoxy-D-xylulose-5-phosphate isomeroreductase activity|DOXP reductoisomerase activity|1-deoxyxylulose-5-phosphate reductoisomerase activity|DXP-reductoisomerase activity|2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity											EC:1.1.1.267|MetaCyc:DXPREDISOM-RXN|KEGG_REACTION:R05688|RHEA:13717		molecular_function											owl:Class	
GO:0043135	biolink:NamedThing	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+.	got7fsn_ti	PRPP pyrophosphatase activity											MetaCyc:RXN-10969		molecular_function											owl:Class	
GO:0010348	biolink:NamedThing	lithium:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in).	got7fsn_ti	lithium:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0034468	biolink:NamedThing	glycosome lumen	The volume enclosed by the membrane of a glycosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0036367	biolink:NamedThing	light adaption	The ability of a photoreceptor to adjust to varying levels of light.	got7fsn_ti					Light adaptation is usually a combination of cell desensitization and response acceleration.		bf	2012-09-26T13:28:14Z						biological_process											owl:Class	
GO:0071373	biolink:NamedThing	cellular response to luteinizing hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.	got7fsn_ti							mah	2009-12-11T03:16:02Z						biological_process											owl:Class	
GO:0034699	biolink:NamedThing	response to luteinizing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.	got7fsn_ti	response to luteinizing hormone stimulus													biological_process											owl:Class	
GO:0047899	biolink:NamedThing	formate dehydrogenase (NADP+) activity	Catalysis of the reaction: formate + NADP(+) = CO(2) + NADPH.	got7fsn_ti	NADP-dependent formate dehydrogenase activity|formate:NADP+ oxidoreductase activity											KEGG_REACTION:R00134|EC:1.17.1.10|RHEA:12000|MetaCyc:FORMATE-DEHYDROGENASE-NADP+-RXN		molecular_function											owl:Class	
GO:0009700	biolink:NamedThing	indole phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.	got7fsn_ti	indole phytoalexin synthesis|indole phytoalexin anabolism|indole phytoalexin biosynthesis|indole phytoalexin formation													biological_process											owl:Class	
GO:0106293	biolink:NamedThing	NADH oxidase H202-forming activity	Catalysis of the reaction: NADH + H+ + O2 = NAD + hydrogen peroxide (H2O2).	got7fsn_ti							hjd	2020-08-19T17:35:22Z				RHEA:11264		molecular_function											owl:Class	
GO:0047992	biolink:NamedThing	hydroxylysine kinase activity	Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H(+).	got7fsn_ti	hydroxylysine kinase (phosphorylating)|GTP:5-hydroxy-L-lysine O-phosphotransferase activity|guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase activity											EC:2.7.1.81|Reactome:R-HSA-6788611|RHEA:19049|MetaCyc:HYDROXYLYSINE-KINASE-RXN|KEGG_REACTION:R03378		molecular_function											owl:Class	
GO:0102178	biolink:NamedThing	4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol + O2 + NADH <=> 4alpha-carboxy-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-11932|RHEA:58880		molecular_function											owl:Class	
GO:0070654	biolink:NamedThing	sensory epithelium regeneration	The regrowth of a sensory epithelium following its loss or destruction.	got7fsn_ti							mah	2009-05-28T04:02:27Z						biological_process											owl:Class	
GO:0008314	biolink:NamedThing	gurken signaling pathway	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to a ligand Gurken.	got7fsn_ti	gurken receptor signaling pathway|gurken-activated signaling pathway|signaling by Gurken|gurken receptor signalling pathway													biological_process											owl:Class	
GO:0102158	biolink:NamedThing	very-long-chain 3-hydroxyacyl-CoA dehydratase activity	Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain trans-2,3-dehydroacyl-CoA.	got7fsn_ti												MetaCyc:RXN-11750|RHEA:45812|EC:4.2.1.134		molecular_function											owl:Class	
GO:0018442	biolink:NamedThing	peptidyl-glutamic acid esterification	The addition of an ester group to a glutamic acid residue in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0046783	biolink:NamedThing	modification by virus of host polysomes	Any viral process that interferes with and inhibits the assembly and function of polysomes.	got7fsn_ti	viral perturbation of polysomes				See also the cellular component term 'polysome ; GO:0005844'.									biological_process											owl:Class	
GO:0061769	biolink:NamedThing	ribosylnicotinate kinase activity	Catalysis of the reaction: N-ribosylnicotinate + ATP = ADP + 2 H(+) + nicotinate mononucleotide.	got7fsn_ti							dph	2016-05-05T14:41:44Z				Reactome:R-HSA-8869607|Reactome:R-HSA-8869606		molecular_function											owl:Class	
GO:0032491	biolink:NamedThing	detection of molecule of fungal origin	The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal.	got7fsn_ti	detection of fungal associated molecule|detection of fungus associated molecule													biological_process											owl:Class	
GO:0045610	biolink:NamedThing	regulation of hemocyte differentiation	Any process that modulates the frequency, rate or extent of hemocyte differentiation.	got7fsn_ti	regulation of arthropod blood cell differentiation													biological_process											owl:Class	
GO:0030921	biolink:NamedThing	peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.	got7fsn_ti												RESID:AA0183		biological_process											owl:Class	
GO:0035890	biolink:NamedThing	exit from host	The directed movement of an organism out of the body, tissues or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	ejection from host						bf	2011-06-15T02:08:03Z						biological_process											owl:Class	
GO:0048803	biolink:NamedThing	imaginal disc-derived male genitalia morphogenesis	The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc.	got7fsn_ti	male genital morphogenesis													biological_process											owl:Class	
GO:0045461	biolink:NamedThing	sterigmatocystin biosynthetic process	The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	got7fsn_ti	sterigmatocystin anabolism|sterigmatocystin formation|sterigmatocystin synthesis|sterigmatocystin biosynthesis													biological_process											owl:Class	
GO:0000124	biolink:NamedThing	SAGA complex	A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).	got7fsn_ti	Spt-Ada-Gcn5-acetyltransferase complex|STAGA complex|SPT3-TAF9-PCAF acetylase complex|STAGA coactivator complex|PCAF histone acetylase-associated complex|PCAF complex|SPT3-TAF9-GCN5 acetylase complex										GO:0030914|GO:0000125			cellular_component											owl:Class	
GO:0097198	biolink:NamedThing	histone H3-K36 trimethylation	The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone.	got7fsn_ti							pr	2011-12-05T01:19:45Z						biological_process											owl:Class	
GO:1990696	biolink:NamedThing	USH2 complex	A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7.	got7fsn_ti	USH2 quaternary protein complex						krc	2015-03-12T17:29:18Z						cellular_component											owl:Class	
GO:0098762	biolink:NamedThing	meiotic cell cycle phase	One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.	got7fsn_ti					This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0050630	biolink:NamedThing	(iso)eugenol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.	got7fsn_ti	isoeugenol O-methyltransferase activity|S-adenosyl-L-methionine:isoeugenol O-methyltransferase activity											EC:2.1.1.146|MetaCyc:2.1.1.146-RXN|RHEA:17081		molecular_function											owl:Class	
GO:0060651	biolink:NamedThing	regulation of epithelial cell proliferation involved in mammary gland bud elongation	Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud.	got7fsn_ti							dph	2009-05-29T08:57:18Z						biological_process											owl:Class	
GO:0038102	biolink:NamedThing	activin receptor antagonist activity	Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.	got7fsn_ti					This term refers to inhibition of a member of the activin receptor family; activin receptors bind to multiple ligands including activin and nodal.		bf	2012-02-17T11:28:59Z						molecular_function											owl:Class	
GO:0002314	biolink:NamedThing	germinal center B cell differentiation	The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).	got7fsn_ti	germinal center B lymphocyte differentiation|germinal center B-cell differentiation|germinal center B-lymphocyte differentiation|germinal center B cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0034852	biolink:NamedThing	4,4-dimethyl-3-oxopentanal dehydrogenase activity	Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1309		molecular_function											owl:Class	
GO:0050022	biolink:NamedThing	L-arabinose 1-dehydrogenase (NAD+) activity	Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH.	got7fsn_ti	L-arabinose:NAD+ 1-oxidoreductase activity|L-arabinose 1-dehydrogenase activity											EC:1.1.1.46|MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN|RHEA:17925		molecular_function											owl:Class	
GO:0090676	biolink:NamedThing	calcium ion transmembrane transport via low voltage-gated calcium channel	A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel.	got7fsn_ti	generation of T-type calcium current						tb	2016-03-23T10:15:23Z						biological_process											owl:Class	
GO:0003070	biolink:NamedThing	regulation of systemic arterial blood pressure by neurotransmitter	The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.	got7fsn_ti														biological_process											owl:Class	
GO:0061651	biolink:NamedThing	Atg12 conjugating enzyme activity	Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2						dph	2014-11-06T13:17:36Z						molecular_function											owl:Class	
GO:0070384	biolink:NamedThing	Harderian gland development	The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.	got7fsn_ti					Note that the Harderian gland is found in all terrestrial vertebrate groups, including amphibia, reptiles, birds, and mammals. However, it appears to be absent in certain mammals such as bats, cows, horses, and higher primates. Though largely absent in the adult human, it is present in the fetal and neonatal stages.									biological_process											owl:Class	
GO:0006933	biolink:NamedThing	negative regulation of cell adhesion involved in substrate-bound cell migration	The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.	got7fsn_ti	substrate-bound cell migration, cell release from substrate													biological_process											owl:Class	
GO:0043280	biolink:NamedThing	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.	got7fsn_ti	positive regulation of caspase activity|activation of caspase activity|up regulation of caspase activity|stimulation of caspase activity|upregulation of caspase activity|up-regulation of caspase activity													biological_process											owl:Class	
GO:0075317	biolink:NamedThing	ascus development	The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.	got7fsn_ti					Note that ascospores and asci are separate biological structures. The ascus is the structure that contain the ascospores, but the development of the ascus is a different process than the formation of the ascospores themselves; for instance, some mutations affect sporulation without affecting ascus development. For this reason, GO:0030437 ascospore formation and GO:0075317 ascus development are different terms and are not linked.									biological_process											owl:Class	
GO:0000810	biolink:NamedThing	diacylglycerol diphosphate phosphatase activity	Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.	got7fsn_ti	diacylglycerol pyrophosphate phosphatase activity|DGPP phosphohydrolase activity|DGPP phosphatase activity											RHEA:27449|MetaCyc:RXN-11277|EC:3.1.3.81		molecular_function											owl:Class	
GO:0052602	biolink:NamedThing	4-chloronitrobenzene nitroreductase activity	Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O.	got7fsn_ti												UM-BBD_enzymeID:e0245|MetaCyc:RXN-8833		molecular_function											owl:Class	
GO:0051730	biolink:NamedThing	GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA.	got7fsn_ti	GTP-dependent polyribonucleotide kinase activity|GTP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|GTP-dependent RNA kinase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP-dependent RNA 5'-hydroxyl-kinase activity													molecular_function											owl:Class	
GO:0010150	biolink:NamedThing	leaf senescence	The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0102523	biolink:NamedThing	2-chloroacrylate reductase activity	Catalysis of the reaction: (S)-2-chloropropanoate + NADP <=> 2-chloroacrylate + NADPH + H+.	got7fsn_ti												EC:1.3.1.103|RHEA:36591|MetaCyc:RXN-14536		molecular_function											owl:Class	
GO:0099564	biolink:NamedThing	modification of synaptic structure, modulating synaptic transmission	Any process that modulates synaptic transmission via modification of the structure of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0099563	biolink:NamedThing	modification of synaptic structure	Any process that modifies the structure/morphology of a synapse.	got7fsn_ti	synapse remodelling				This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones.									biological_process											owl:Class	
GO:0019769	biolink:NamedThing	low-affinity IgE receptor activity	Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	low affinity IgE receptor activity|low affinity Fc receptor activity													molecular_function											owl:Class	
GO:0006837	biolink:NamedThing	serotonin transport	The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.	got7fsn_ti														biological_process											owl:Class	
GO:0052685	biolink:NamedThing	perillic acid-CoA ligase (ADP-forming) activity	Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA.	got7fsn_ti	perillic acid:CoA ligase (ADP-forming) activity|perillyl-CoA synthetase activity											EC:6.2.1.-|KEGG_REACTION:R06367		molecular_function											owl:Class	
GO:0043122	biolink:NamedThing	regulation of I-kappaB kinase/NF-kappaB signaling	Any process that modulates I-kappaB kinase/NF-kappaB signaling.	got7fsn_ti	regulation of I-kappaB kinase/NF-kappaB cascade													biological_process											owl:Class	
GO:0090675	biolink:NamedThing	intermicrovillar adhesion	The biological adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.	got7fsn_ti							tb	2016-02-19T13:34:07Z						biological_process											owl:Class	
GO:0004823	biolink:NamedThing	leucine-tRNA ligase activity	Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu).	got7fsn_ti	leucyl-transfer ribonucleate synthetase activity|leucine-tRNA synthetase activity|L-leucine:tRNALeu ligase (AMP-forming)|leucine translase activity|leucyl-tRNA synthetase activity|leucyl-transfer RNA synthetase activity|leucyl-transfer ribonucleic acid synthetase activity											Reactome:R-HSA-380200|Reactome:R-HSA-379974|KEGG_REACTION:R03657|EC:6.1.1.4|RHEA:11688|MetaCyc:LEUCINE--TRNA-LIGASE-RXN		molecular_function											owl:Class	
GO:0035994	biolink:NamedThing	response to muscle stretch	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length.	got7fsn_ti							bf	2011-08-30T01:52:31Z						biological_process											owl:Class	
GO:0002349	biolink:NamedThing	histamine production involved in inflammatory response	The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	histamine production involved in acute inflammatory response													biological_process											owl:Class	
GO:0034829	biolink:NamedThing	2-hydroxydec-2,4-diene-1,10-dioate hydratase activity	Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate.	got7fsn_ti												UM-BBD_reactionID:r1172		molecular_function											owl:Class	
GO:0031267	biolink:NamedThing	small GTPase binding	Binding to a small monomeric GTPase.	got7fsn_ti	ADP-ribosylation factor binding|Ran protein binding|Ras interactor activity|Rab escort protein activity|Rab GTPase binding|Ran-binding protein|Rac GTPase binding|Rab interactor activity|ARF binding|GTP-Ral binding|Ran GTPase binding|Rho GTPase binding|Ral GTPase binding|GTP-Rho binding|REP|Ras GTPase binding	https://github.com/geneontology/go-ontology/issues/18750									GO:0017048|GO:0005084|GO:0034989|GO:0048365|GO:0017031|GO:0017016|GO:0017160|GO:0008536|GO:0017049|GO:0030306|GO:0017137			molecular_function											owl:Class	
GO:0051020	biolink:NamedThing	GTPase binding	Binding to a GTPase, any enzyme that catalyzes the hydrolysis of GTP.	got7fsn_ti														molecular_function											owl:Class	
GO:0033189	biolink:NamedThing	response to vitamin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.	got7fsn_ti	response to retinol													biological_process											owl:Class	
GO:0047884	biolink:NamedThing	FAD diphosphatase activity	Catalysis of the reaction: FAD + H2O = AMP + FMN.	got7fsn_ti	FAD pyrophosphatase activity|riboflavine adenine dinucleotide pyrophosphatase activity|FAD nucleotidohydrolase activity|riboflavin adenine dinucleotide pyrophosphatase activity|flavin adenine dinucleotide pyrophosphatase activity|flavine adenine dinucleotide pyrophosphatase activity|FAD pyrophosphohydrolase activity											RHEA:13889|MetaCyc:FAD-PYROPHOSPHATASE-RXN|EC:3.6.1.18		molecular_function											owl:Class	
GO:0047424	biolink:NamedThing	methylenediurea deaminase activity	Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea.	got7fsn_ti	methylenediurea aminohydrolase activity|methylenediurease activity											RHEA:15929|EC:3.5.3.21|MetaCyc:3.5.3.21-RXN		molecular_function											owl:Class	
GO:0075214	biolink:NamedThing	spore encystment	The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	spore encystment on host													biological_process											owl:Class	
GO:0006376	biolink:NamedThing	mRNA splice site selection	Selection of a splice site by components of the assembling spliceosome.	got7fsn_ti	spliceosomal E complex biosynthesis|spliceosomal E complex formation|spliceosomal commitment complex biosynthesis|spliceosomal commitment complex formation													biological_process											owl:Class	
GO:0072539	biolink:NamedThing	T-helper 17 cell differentiation	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.	got7fsn_ti	T-helper 17 cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.		mah	2011-01-17T11:18:47Z						biological_process											owl:Class	
GO:0018764	biolink:NamedThing	N-isopropylammelide isopropylaminohydrolase activity	Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine.	got7fsn_ti	AtzC											EC:3.5.4.42|MetaCyc:R123-RXN|UM-BBD_enzymeID:e0086|RHEA:23608		molecular_function											owl:Class	
GO:0019923	biolink:NamedThing	alpha-1-microglobulin-chromophore linkage	The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds.	got7fsn_ti												RESID:AA0224		biological_process											owl:Class	
GO:0043683	biolink:NamedThing	type IV pilus assembly	The assembly from its constituent parts of a type IV pilus.	got7fsn_ti	type IV fimbrial biogenesis|type IV fimbriae biogenesis|type IV fimbrial assembly|type IV fimbria biogenesis|type IV fimbria assembly|type IV pilus biogenesis|type IV fimbrium assembly|type IV fimbriae assembly|type IV fimbrium biogenesis	https://github.com/geneontology/go-ontology/issues/14579												biological_process											owl:Class	
GO:0009297	biolink:NamedThing	pilus assembly	The assembly from its constituent parts of a pilus, a short filamentous structure of bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles.	got7fsn_ti	fimbriae assembly|pilus biogenesis|fimbrial assembly|pilus formation|fimbrium assembly|fimbria biogenesis|fimbriae biogenesis|fimbrium biogenesis|fimbria assembly	https://github.com/geneontology/go-ontology/issues/14579												biological_process											owl:Class	
GO:0023041	biolink:NamedThing	neuronal signal transduction	The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.	got7fsn_ti								2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0036124	biolink:NamedThing	histone H3-K9 trimethylation	The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone.	got7fsn_ti							bf	2012-02-20T03:08:06Z						biological_process											owl:Class	
GO:0072193	biolink:NamedThing	ureter smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.	got7fsn_ti							mah	2010-03-01T01:55:01Z						biological_process											owl:Class	
GO:0043097	biolink:NamedThing	pyrimidine nucleoside salvage	Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0006191	biolink:NamedThing	deoxyinosine salvage	Any process that generates deoxyinosine from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0036384	biolink:NamedThing	cytidine-diphosphatase activity	Catalysis of the reaction: CDP + H2O = CMP + phosphate.	got7fsn_ti	CDPase activity						bf	2013-05-23T13:33:01Z				RHEA:64880		molecular_function											owl:Class	
GO:0102273	biolink:NamedThing	homophytochelatin synthase (dimmer forming) activity	Catalysis of the reaction: glutathionate + L-gamma-glutamyl-L-cysteinyl-beta-alaninate <=> gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine.	got7fsn_ti												MetaCyc:RXN-12529		molecular_function											owl:Class	
GO:0070843	biolink:NamedThing	misfolded protein transport	The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.	got7fsn_ti							mah	2009-07-31T12:50:00Z						biological_process											owl:Class	
GO:0071719	biolink:NamedThing	sodium-independent leukotriene transport	The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.	got7fsn_ti							mah	2010-03-10T03:08:42Z						biological_process											owl:Class	
GO:0071716	biolink:NamedThing	leukotriene transport	The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.	got7fsn_ti							mah	2010-03-10T02:53:59Z						biological_process											owl:Class	
GO:0009597	biolink:NamedThing	detection of virus	The series of events in which a stimulus from a virus is received and converted into a molecular signal.	got7fsn_ti	perception of virus				GO:0009597 is not a child term of 'detection of symbiont ; GO:0009602' to allow annotation of a virus responding to another (often competing) virus.									biological_process											owl:Class	
GO:0009615	biolink:NamedThing	response to virus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.	got7fsn_ti	response to viruses													biological_process											owl:Class	
GO:0008431	biolink:NamedThing	vitamin E binding	Binding to a vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.	got7fsn_ti	tocopherol binding|alpha-tocopherol binding													molecular_function											owl:Class	
GO:0021677	biolink:NamedThing	rhombomere 8 formation	The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:2000829	biolink:NamedThing	negative regulation of parathyroid hormone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion.	got7fsn_ti	negative regulation of parathormone secretion|negative regulation of PTH secretion|negative regulation of parathyrin secretion						bf	2011-07-26T08:37:57Z						biological_process											owl:Class	
GO:0015301	biolink:NamedThing	anion:anion antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).	got7fsn_ti	anion exchanger activity|bicarbonate:chloride antiporter										GO:0015380|GO:0015384	Reactome:R-HSA-561041		molecular_function											owl:Class	
GO:1990197	biolink:NamedThing	methionine-importing ABC transporter complex	An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regarded as the periplasmic methionine-binding chaperon subunit, and is capable of transporting methionine from the periplasm into the cytoplasm in an ATP-dependent manner.	got7fsn_ti	MetNI complex|MetNIQ transport complex|MetNI transporter|MetNI transporter complex|methionine transporter complex, ATP-dependent|methionine transport complex|ATP-binding cassette (ABC) methionine importer complex|ATP-dependent methionine-importing complex|ATP-dependent methionine importer complex|MetNIQ transporter complex|methionine transporter|MetNI transport complex|ATP-dependent methionine importing complex|MetNIQ transporter|MetNIQ complex|methionine transporter complex	https://github.com/geneontology/go-ontology/issues/21619					bhm	2013-09-26T09:38:26Z						cellular_component											owl:Class	
GO:0032030	biolink:NamedThing	myosin I light chain binding	Binding to a light chain of a myosin I complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0002279	biolink:NamedThing	mast cell activation involved in immune response	The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	mast cell activation during immune response													biological_process											owl:Class	
GO:0001197	biolink:NamedThing	positive regulation of mating-type specific transcription from RNA polymerase II promoter	Any mating-type specific process that activates or increases the rate of transcription from an RNA polymerase II promoter.	got7fsn_ti	up regulation of transcription from an RNA polymerase II promoter, mating-type specific|up-regulation of transcription from an RNA polymerase II promoter, mating-type specific|activation of transcription from an RNA polymerase II promoter, mating-type specific|stimulation of transcription from an RNA polymerase II promoter, mating-type specific|upregulation of transcription from an RNA polymerase II promoter, mating-type specific						krc	2011-11-23T09:31:33Z						biological_process											owl:Class	
GO:0009638	biolink:NamedThing	phototropism	The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.	got7fsn_ti												Wikipedia:Phototropism		biological_process											owl:Class	
GO:0090329	biolink:NamedThing	regulation of DNA-dependent DNA replication	Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.	got7fsn_ti							tb	2010-05-14T10:42:04Z						biological_process											owl:Class	
GO:0080127	biolink:NamedThing	fruit septum development	The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit.	got7fsn_ti							dhl	2009-04-28T04:37:19Z						biological_process											owl:Class	
GO:0097750	biolink:NamedThing	endosome membrane tubulation	A membrane tubulation process occurring in an endosome membrane.	got7fsn_ti	endosomal membrane tubulation						pr	2016-12-21T12:33:09Z						biological_process											owl:Class	
GO:0097749	biolink:NamedThing	membrane tubulation	A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules).	got7fsn_ti							pr	2016-12-21T12:32:24Z						biological_process											owl:Class	
GO:0009646	biolink:NamedThing	response to absence of light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.	got7fsn_ti	response to darkness													biological_process											owl:Class	
GO:0052572	biolink:NamedThing	response to host immune response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response to immune response of other organism involved in symbiotic interaction										GO:0052564			biological_process											owl:Class	
GO:0010442	biolink:NamedThing	guard cell morphogenesis	Generation and organization of the polarized cell that is capable of turgor driven movement.	got7fsn_ti	guard cell morphogenesis during differentiation													biological_process											owl:Class	
GO:0017013	biolink:NamedThing	protein flavinylation	The addition of a flavin group to a protein amino acid.	got7fsn_ti	protein amino acid flavinylation													biological_process											owl:Class	
GO:1903706	biolink:NamedThing	regulation of hemopoiesis	Any process that modulates the frequency, rate or extent of hemopoiesis.	got7fsn_ti	regulation of hematopoiesis|regulation of haemopoiesis|regulation of blood cell formation|regulation of blood cell biosynthesis				An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.		pad	2014-12-04T15:34:13Z						biological_process											owl:Class	
GO:0008993	biolink:NamedThing	rhamnulokinase activity	Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate.	got7fsn_ti	L-rhamnulokinase activity|RhuK|ATP:L-rhamnulose 1-phosphotransferase activity|L-rhamnulose kinase activity|rhamnulose kinase activity|rhamnulokinase (phosphorylating)											MetaCyc:RHAMNULOKIN-RXN|RHEA:20117|EC:2.7.1.5		molecular_function											owl:Class	
GO:1900551	biolink:NamedThing	N',N'',N'''-triacetylfusarinine C biosynthetic process	The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C.	got7fsn_ti	N',N'',N'''-triacetylfusarinine C synthesis|N',N'',N'''-triacetylfusarinine C formation|N',N'',N'''-triacetylfusarinine C anabolism|N',N'',N'''-triacetylfusarinine C biosynthesis						di	2012-05-15T01:00:58Z						biological_process											owl:Class	
GO:0000016	biolink:NamedThing	lactase activity	Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.	got7fsn_ti	lactose galactohydrolase activity|lactase-phlorizin hydrolase activity											EC:3.2.1.108|Reactome:R-HSA-5658001|Reactome:R-HSA-189062|RHEA:10076|MetaCyc:LACTASE-RXN		molecular_function											owl:Class	
GO:0033244	biolink:NamedThing	regulation of penicillin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti	regulation of penicillin metabolism													biological_process											owl:Class	
GO:0018857	biolink:NamedThing	2,4-dichlorobenzoate-CoA ligase activity	Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0137		molecular_function											owl:Class	
GO:0060009	biolink:NamedThing	Sertoli cell development	The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0003998	biolink:NamedThing	acylphosphatase activity	Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.	got7fsn_ti	acetic phosphatase activity|1,3-diphosphoglycerate phosphatase activity|acetylphosphatase activity|GP 1-3|Ho 1-3|acylphosphate phosphohydrolase activity											RHEA:14965|EC:3.6.1.7|MetaCyc:ACYLPHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0008657	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity	Binds to and stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.	got7fsn_ti	DNA gyrase inhibitor activity													molecular_function											owl:Class	
GO:0030652	biolink:NamedThing	peptide antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.	got7fsn_ti	peptide antibiotic degradation|peptide antibiotic breakdown|peptide antibiotic catabolism													biological_process											owl:Class	
GO:0045017	biolink:NamedThing	glycerolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.	got7fsn_ti	glycerolipid anabolism|glycerolipid formation|glycerolipid biosynthesis|glycerolipid synthesis													biological_process											owl:Class	
GO:1990472	biolink:NamedThing	piRNA dual-strand cluster binding	Binding to dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription.	got7fsn_ti					An example of this is rhi in Drosophila melanogaster (Q7JXA8) in PMID:24906153 (inferred from direct assay).		bhm	2014-08-29T14:50:54Z						molecular_function											owl:Class	
GO:1990470	biolink:NamedThing	piRNA cluster binding	Binding to piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs).	got7fsn_ti					An example of this is rhi in Drosophila melanogaster (Q7JXA8) in PMID:24906153 (inferred from direct assay).		bhm	2014-08-29T14:23:38Z						molecular_function											owl:Class	
GO:0019499	biolink:NamedThing	cyanide metabolic process	The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain.	got7fsn_ti	cyanide metabolism													biological_process											owl:Class	
GO:0061534	biolink:NamedThing	gamma-aminobutyric acid secretion, neurotransmission	The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-21T16:10:50Z						biological_process											owl:Class	
GO:0047813	biolink:NamedThing	D-arabinitol 4-dehydrogenase activity	Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH.	got7fsn_ti												MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN|EC:1.1.1.11|RHEA:17921		molecular_function											owl:Class	
GO:0004059	biolink:NamedThing	aralkylamine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.	got7fsn_ti	arylalkylamine N-acetyltransferase activity|acetyl-CoA:2-arylethylamine N-acetyltransferase activity|AANAT activity|melatonin rhythm enzyme activity|serotonin N-acetyltransferase activity|serotonin acetyltransferase activity|serotonin acetylase activity											RHEA:20497|EC:2.3.1.87|MetaCyc:ARALKYLAMINE-N-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-209792		molecular_function											owl:Class	
GO:0060309	biolink:NamedThing	elastin catabolic process	The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.	got7fsn_ti	elastin catabolism|elastin degradation|elastin breakdown													biological_process											owl:Class	
GO:0098810	biolink:NamedThing	neurotransmitter reuptake	The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:0034820	biolink:NamedThing	4,9-DSHA hydrolase activity	Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+.	got7fsn_ti												UM-BBD_reactionID:r1152		molecular_function											owl:Class	
GO:0008756	biolink:NamedThing	o-succinylbenzoate-CoA ligase activity	Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate.	got7fsn_ti	o-succinylbenzoyl-CoA synthetase activity|o-succinylbenzoate:CoA ligase (AMP-forming)|2-succinylbenzoate:CoA ligase (AMP-forming)|o-succinylbenzoyl-coenzyme A synthetase activity|OSB-CoA synthetase activity											KEGG_REACTION:R04030|EC:6.2.1.26|RHEA:17009|MetaCyc:O-SUCCINYLBENZOATE-COA-LIG-RXN		molecular_function											owl:Class	
GO:0000279	biolink:NamedThing	M phase	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.	got7fsn_ti	M-phase				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:M_phase		biological_process											owl:Class	
GO:0039618	biolink:NamedThing	T=pseudo3 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.	got7fsn_ti					T=pseudo3 capsids are not T=3 symmetry as described by Caspar and Klug (PMID:14019094) because the basic unit is composed of three different proteins. Since the three subunits are morphologically very similar, the structure is therefore a pseudo T=3.		bf	2012-07-18T02:10:02Z				VZ:809		cellular_component											owl:Class	
GO:0005243	biolink:NamedThing	gap junction channel activity	A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.	got7fsn_ti	intercellular channel|connexin|innexin channel activity|innexin										GO:0015285|GO:0015286	Reactome:R-HSA-375340|Reactome:R-HSA-375342|Reactome:R-HSA-375339|Reactome:R-HSA-190681|Reactome:R-HSA-375330		molecular_function											owl:Class	
GO:0022829	biolink:NamedThing	wide pore channel activity	Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.	got7fsn_ti	non-gated, wide pore channel activity|gap junction activity													molecular_function											owl:Class	
GO:1900160	biolink:NamedThing	plastid DNA packaging	Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure.	got7fsn_ti	DNA organisation in plastid|DNA organization in plastid|plastidial DNA packaging						bf	2012-03-08T10:51:50Z						biological_process											owl:Class	
GO:0044878	biolink:NamedThing	mitotic cytokinesis checkpoint signaling	A signaling process that contributes to a mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed.	got7fsn_ti	mitotic cytokinesis checkpoint|signaling pathway involved in mitotic cytokinesis checkpoint|cytokinesis after mitosis checkpoint|defective cytokinesis checkpoint|signal transduction involved in mitotic cytokinesis checkpoint|signalling cascade involved in mitotic cytokinesis checkpoint|signalling pathway involved in mitotic cytokinesis checkpoint	https://github.com/geneontology/go-ontology/issues/20935					jl	2015-01-13T15:30:23Z			GO:1903820			biological_process											owl:Class	
GO:0035970	biolink:NamedThing	peptidyl-threonine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.	got7fsn_ti							bf	2011-08-08T02:57:11Z						biological_process											owl:Class	
GO:0005996	biolink:NamedThing	monosaccharide metabolic process	The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.	got7fsn_ti	monosaccharide metabolism													biological_process											owl:Class	
GO:0072670	biolink:NamedThing	mitochondrial tRNA threonylcarbamoyladenosine modification	The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base).	got7fsn_ti	mitochondrial tRNA t6A modification						mah	2011-02-18T11:34:35Z						biological_process											owl:Class	
GO:0043608	biolink:NamedThing	formamide catabolic process	The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0060175	biolink:NamedThing	brain-derived neurotrophic factor-activated receptor activity	Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	brain-derived neurotrophic factor receptor activity|BDNF-activated receptor activity|BDNF receptor activity				Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand BDNF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.									molecular_function											owl:Class	
GO:1990811	biolink:NamedThing	MWP complex	A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.	got7fsn_ti	Msd1-Wdr8-Pkl1 complex						vw	2015-07-24T13:34:31Z						cellular_component											owl:Class	
GO:0018114	biolink:NamedThing	threonine racemase activity	Catalysis of the reaction: L-threonine = D-threonine.	got7fsn_ti												EC:5.1.1.6|MetaCyc:THREONINE-RACEMASE-RXN|RHEA:13913|KEGG_REACTION:R01467		molecular_function											owl:Class	
GO:0050228	biolink:NamedThing	pterin deaminase activity	Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3.	got7fsn_ti	acrasinase activity|2-amino-4-hydroxypteridine aminohydrolase activity											RHEA:11904|MetaCyc:PTERIN-DEAMINASE-RXN|EC:3.5.4.11		molecular_function											owl:Class	
GO:0060118	biolink:NamedThing	vestibular receptor cell development	The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti	vestibular hair cell development													biological_process											owl:Class	
GO:0070169	biolink:NamedThing	positive regulation of biomineral tissue development	Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.	got7fsn_ti														biological_process											owl:Class	
GO:0007078	biolink:NamedThing	lamin depolymerization	The cell cycle process in which lamin is depolymerized.	got7fsn_ti														biological_process											owl:Class	
GO:0015250	biolink:NamedThing	water channel activity	Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti	aquaporin											Reactome:R-HSA-507870|Reactome:R-HSA-507868|Reactome:R-HSA-432065|Reactome:R-HSA-432054|Reactome:R-HSA-432067|Reactome:R-HSA-445714|RHEA:29667|Reactome:R-HSA-432010		molecular_function											owl:Class	
GO:0009945	biolink:NamedThing	radial axis specification	The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point.	got7fsn_ti														biological_process											owl:Class	
GO:0034515	biolink:NamedThing	proteasome storage granule	An aggregation of proteasome core protease (CP) and regulatory particle (RP) complexes that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state.	got7fsn_ti	PSG	https://github.com/geneontology/go-ontology/issues/20297												cellular_component											owl:Class	
GO:0004358	biolink:NamedThing	glutamate N-acetyltransferase activity	Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine.	got7fsn_ti	ornithine acetyltransferase activity|acetylglutamic-acetylornithine transacetylase activity|N-acetylglutamate synthetase activity|acetylglutamic synthetase activity|glutamate acetyltransferase activity|alpha-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|acetylornithine glutamate acetyltransferase activity|N-acetyl-L-glutamate synthetase activity|ornithine transacetylase activity|acetylglutamate synthetase activity|acetylglutamate-acetylornithine transacetylase activity|N-acetylglutamate synthase activity|N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|acetylornithinase activity											KEGG_REACTION:R02282|RHEA:15349|MetaCyc:GLUTAMATE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.35		molecular_function											owl:Class	
GO:0106266	biolink:NamedThing	3-chloro THPH synthase activity	Catalysis of the reaction: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H+ + 2 H2O.	got7fsn_ti							hjd	2020-06-02T18:13:44Z				RHEA:64356		molecular_function											owl:Class	
GO:0018316	biolink:NamedThing	peptide cross-linking via L-cystine	The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.	got7fsn_ti												RESID:AA0025		biological_process											owl:Class	
GO:0046344	biolink:NamedThing	ecdysteroid catabolic process	The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.	got7fsn_ti	ecdysteroid degradation|ecdysteroid catabolism|ecdysteroid breakdown													biological_process											owl:Class	
GO:0042182	biolink:NamedThing	ketone catabolic process	The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.	got7fsn_ti	ketone breakdown|ketone degradation|ketone catabolism													biological_process											owl:Class	
GO:0003226	biolink:NamedThing	right ventricular compact myocardium morphogenesis	The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.	got7fsn_ti							dph	2009-10-13T10:48:42Z						biological_process											owl:Class	
GO:0042439	biolink:NamedThing	ethanolamine-containing compound metabolic process	The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it.	got7fsn_ti	ethanolamine-containing compound metabolism|ethanolamine and derivative metabolic process|ethanolamine and derivative metabolism													biological_process											owl:Class	
GO:0031713	biolink:NamedThing	B2 bradykinin receptor binding	Binding to a B2 bradykinin receptor.	got7fsn_ti	B2 bradykinin receptor ligand													molecular_function											owl:Class	
GO:0060059	biolink:NamedThing	embryonic retina morphogenesis in camera-type eye	The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.	got7fsn_ti														biological_process											owl:Class	
GO:0008705	biolink:NamedThing	methionine synthase activity	Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine.	got7fsn_ti	N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity|cobalamin-dependent methionine synthase activity|methionine synthase (cobalamin-dependent) activity|B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity|N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity|tetrahydropteroylglutamic methyltransferase activity|5-methyltetrahydrofolate--homocysteine transmethylase activity|tetrahydrofolate methyltransferase activity|N5-methyltetrahydrofolate methyltransferase activity|5-methyltetrahydrofolate--homocysteine S-methyltransferase activity|N(5)-methyltetrahydrofolate methyltransferase activity|tetrahydropteroylglutamate methyltransferase activity|vitamin B12 methyltransferase activity|methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity|B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity|N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity|5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity|N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity|MetH|5-methyltetrahydrofolate-homocysteine S-methyltransferase activity|N-methyltetrahydrofolate:L-homocysteine methyltransferase activity											Reactome:R-HSA-3149539|KEGG_REACTION:R00946|RHEA:11172|EC:2.1.1.13|Reactome:R-HSA-174374|MetaCyc:HOMOCYSMETB12-RXN		molecular_function											owl:Class	
GO:0047625	biolink:NamedThing	adenosylmethionine cyclotransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone.	got7fsn_ti	S-adenosyl-L-methionine alkyltransferase (cyclizing)|adenosyl methionine cyclotransferase activity|adenosylmethioninase activity											KEGG_REACTION:R00180|MetaCyc:ADENOSYLMETHIONINE-CYCLOTRANSFERASE-RXN|EC:2.5.1.4|RHEA:21932		molecular_function											owl:Class	
GO:0042450	biolink:NamedThing	arginine biosynthetic process via ornithine	The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.	got7fsn_ti	arginine anabolism via ornithine|arginine synthesis via ornithine|arginine formation via ornithine													biological_process											owl:Class	
GO:0006591	biolink:NamedThing	ornithine metabolic process	The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.	got7fsn_ti	ornithine metabolism													biological_process											owl:Class	
GO:0051632	biolink:NamedThing	negative regulation of acetylcholine uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.	got7fsn_ti	downregulation of acetylcholine uptake|down regulation of acetylcholine uptake|down-regulation of acetylcholine uptake|negative regulation of acetylcholine import													biological_process											owl:Class	
GO:0051953	biolink:NamedThing	negative regulation of amine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	inhibition of amine transport|down regulation of amine transport|downregulation of amine transport|down-regulation of amine transport													biological_process											owl:Class	
GO:0016432	biolink:NamedThing	tRNA-uridine aminocarboxypropyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine.	got7fsn_ti	S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase activity											EC:2.5.1.25|RHEA:12300|MetaCyc:2.5.1.25-RXN		molecular_function											owl:Class	
GO:0090721	biolink:NamedThing	primary adaptive immune response involving T cells and B cells	An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system.	got7fsn_ti							tb	2016-11-11T12:46:29Z						biological_process											owl:Class	
GO:0090720	biolink:NamedThing	primary adaptive immune response	An adaptive immune response against an antigen not previously encountered by immune system.	got7fsn_ti							tb	2016-11-11T12:44:55Z						biological_process											owl:Class	
GO:0033588	biolink:NamedThing	elongator holoenzyme complex	A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA.	got7fsn_ti	Elongator core complex|Elongator holoenzyme complex	https://github.com/geneontology/go-ontology/issues/22076			Despite its name, this complex is not directly involved in transcriptional elongation (PMID:23165209).						GO:0033589			cellular_component											owl:Class	
GO:0050108	biolink:NamedThing	monoterpenyl-diphosphatase activity	Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate.	got7fsn_ti	monoterpenyl-diphosphate diphosphohydrolase activity|monoterpenyl-pyrophosphatase activity|bornyl pyrophosphate hydrolase activity|bornyl diphosphate hydrolase activity											EC:3.1.7.3|MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0047168	biolink:NamedThing	isocitrate O-dihydroxycinnamoyltransferase activity	Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA.	got7fsn_ti	caffeoyl-CoA:isocitrate 3-O-(3,4-dihydroxycinnamoyl)transferase activity											RHEA:20756|KEGG_REACTION:R01946|EC:2.3.1.126|MetaCyc:2.3.1.126-RXN		molecular_function											owl:Class	
GO:0050106	biolink:NamedThing	monomethyl-sulfatase activity	Catalysis of the reaction: H(2)O + monomethyl sulfate = H(+) + methanol + sulfate.	got7fsn_ti	monomethyl-sulphatase activity|monomethyl-sulfate sulfohydrolase activity											KEGG_REACTION:R01145|RHEA:14221|EC:3.1.6.16|MetaCyc:MONOMETHYL-SULFATASE-RXN		molecular_function											owl:Class	
GO:0008976	biolink:NamedThing	polyphosphate kinase activity	Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).	got7fsn_ti	polyphosphoric acid kinase activity|ATP:polyphosphate phosphotransferase activity|ATP-polyphosphate phosphotransferase activity|polyphosphate polymerase activity											RHEA:19573|MetaCyc:POLYPHOSPHATE-KINASE-RXN|EC:2.7.4.1		molecular_function											owl:Class	
GO:0003298	biolink:NamedThing	physiological muscle hypertrophy	The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.	got7fsn_ti							dph	2009-10-22T09:24:51Z						biological_process											owl:Class	
GO:0006925	biolink:NamedThing	inflammatory cell apoptotic process	Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.	got7fsn_ti	killing of inflammatory cells|programmed cell death, inflammatory cells|inflammatory cell apoptosis|inflammatory cell programmed cell death by apoptosis|programmed cell death of inflammatory cells by apoptosis|apoptosis of inflammatory cells													biological_process											owl:Class	
GO:0033229	biolink:NamedThing	cysteine transmembrane transporter activity	Enables the transfer of cysteine from one side of a membrane to the other.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17289										RHEA:32795		molecular_function											owl:Class	
GO:0050134	biolink:NamedThing	N6-methyl-lysine oxidase activity	Catalysis of the reaction: N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2).	got7fsn_ti	6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating)|epsilon-alkyllysinase activity|N6-methyl-L-lysine:oxygen oxidoreductase (demethylating)|epsilon-N-methyllysine demethylase activity|N(6)-methyllysine oxidase activity|epsilon-alkyl-L-lysine:oxygen oxidoreductase activity|N6-methyllysine oxidase activity											MetaCyc:N6-METHYL-LYSINE-OXIDASE-RXN|RHEA:23200|EC:1.5.3.4|KEGG_REACTION:R00612		molecular_function											owl:Class	
GO:0050117	biolink:NamedThing	N-acetyl-beta-alanine deacetylase activity	Catalysis of the reaction: N-acetyl-beta-alanine + H(2)O = beta-alanine + acetate.	got7fsn_ti	N-acetyl-beta-alanine amidohydrolase activity											MetaCyc:N-ACETYL-BETA-ALANINE-DEACETYLASE-RXN|KEGG_REACTION:R00909|RHEA:23212|EC:3.5.1.21		molecular_function											owl:Class	
GO:1900796	biolink:NamedThing	terrequinone A biosynthetic process	The chemical reactions and pathways resulting in the formation of terrequinone A.	got7fsn_ti	terrequinone A biosynthesis|terrequinone A anabolism|terrequinone A synthesis|terrequinone A formation						di	2012-06-04T09:45:48Z						biological_process											owl:Class	
GO:0002443	biolink:NamedThing	leukocyte mediated immunity	Any process involved in the carrying out of an immune response by a leukocyte.	got7fsn_ti	leukocyte immune effector process|leucocyte mediated immunity|cellular immune response|immune cell mediated immunity|immune cell effector process|leucocyte immune effector process|cell-mediated immune response										GO:0019723|GO:0042087			biological_process											owl:Class	
GO:0061969	biolink:NamedThing	maintenance of left sidedness	The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves.	got7fsn_ti							dph	2018-02-12T16:41:30Z						biological_process											owl:Class	
GO:0032577	biolink:NamedThing	phosphatidylcholine:cardiolipin O-linoleoyltransferase activity	Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.	got7fsn_ti	phosphatidylcholine:cardiolipin linoleoyltransferase													molecular_function											owl:Class	
GO:0032576	biolink:NamedThing	O-linoleoyltransferase activity	Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0044760	biolink:NamedThing	modulation by symbiont of host cholinergic synaptic transmission	Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.	got7fsn_ti	regulation by symbiont of host cholinergic synaptic transmission						jl	2012-12-06T15:39:46Z						biological_process											owl:Class	
GO:0044758	biolink:NamedThing	modulation by symbiont of host synaptic transmission	Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.	got7fsn_ti	regulation by symbiont of host synaptic transmission						jl	2012-12-06T15:34:05Z						biological_process											owl:Class	
GO:0018390	biolink:NamedThing	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine	The methyl esterification of peptidyl-glutamic acid or peptidyl-glutamine to form the derivative glutamic acid 5-methyl ester.	got7fsn_ti	peptidyl-L-glutamic acid 5-methyl ester synthesis from peptidyl-glutamic acid or peptidyl-glutamine|peptidyl-L-glutamic acid 5-methyl ester formation from peptidyl-glutamic acid or peptidyl-glutamine|peptidyl-L-glutamic acid 5-methyl ester anabolism from peptidyl-glutamic acid or peptidyl-glutamine											RESID:AA0072		biological_process											owl:Class	
GO:0021947	biolink:NamedThing	outward migration of deep nuclear neurons	The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate.	got7fsn_ti														biological_process											owl:Class	
GO:1990340	biolink:NamedThing	laminin-15 complex	A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains.	got7fsn_ti	laminin-523						bhm	2014-03-20T23:48:25Z						cellular_component											owl:Class	
GO:0010295	biolink:NamedThing	(+)-abscisic acid 8'-hydroxylase activity	Catalysis of the reaction: (+)-abscisate + H(+) + NADPH + O(2) = (+)-8'-hydroxyabscisate + H(2)O + NADP(+).	got7fsn_ti	abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating)|ABA 8'-hydroxylase activity|abscisic acid 8'-hydroxylase activity|ABA 8'-Hydroxylase activity, Abscisate 8'-hydroxylase activity|(+)-ABA 8'-hydroxylase activity											MetaCyc:1.14.13.93-RXN|RHEA:12897|KEGG_REACTION:R07202|EC:1.14.14.137		molecular_function											owl:Class	
GO:0061834	biolink:NamedThing	actin filament branch point	The part of an actin filament where the structure forks.	got7fsn_ti	microfilament branch point													cellular_component											owl:Class	
GO:0030798	biolink:NamedThing	trans-aconitate 2-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine.	got7fsn_ti	S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase activity											KEGG_REACTION:R05763|EC:2.1.1.144|MetaCyc:RXN0-2441|RHEA:14969		molecular_function											owl:Class	
GO:0036338	biolink:NamedThing	viral membrane	The lipid bilayer of a virion, a complete fully infectious extracellular virus particle.	got7fsn_ti							bf	2012-09-07T13:28:21Z						cellular_component											owl:Class	
GO:0102274	biolink:NamedThing	glutathione S-conjugate carboxypeptidase activity	Catalysis of the reaction: H2O + a glutathione-toxin conjugate <=> glycine + a [Glu-Cys]-S-conjugate.	got7fsn_ti												MetaCyc:RXN-12532		molecular_function											owl:Class	
GO:0047874	biolink:NamedThing	dolichyldiphosphatase activity	Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate.	got7fsn_ti	dolichyl pyrophosphatase activity|dolichyl diphosphate phosphohydrolase activity|dolichol diphosphatase activity|dolichyl-diphosphate phosphohydrolase activity											MetaCyc:DOLICHYLDIPHOSPHATASE-RXN|EC:3.6.1.43|Reactome:R-HSA-446200|RHEA:14385		molecular_function											owl:Class	
GO:0017190	biolink:NamedThing	N-terminal peptidyl-aspartic acid acetylation	The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.	got7fsn_ti					See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'.							RESID:AA0042		biological_process											owl:Class	
GO:0001757	biolink:NamedThing	somite specification	The process in which individual somites establish identity during embryogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:0032005	biolink:NamedThing	signal transduction involved in positive regulation of conjugation with cellular fusion	The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0055039	biolink:NamedThing	trichocyst	A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in net-like structures, to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft.	got7fsn_ti												Wikipedia:Trichocyst		cellular_component											owl:Class	
GO:0047671	biolink:NamedThing	anthranilate adenylyltransferase activity	Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H(+).	got7fsn_ti	ATP:anthranilate adenylyltransferase activity|ATP:anthranilate N-adenylyltransferase activity|anthranilic acid adenylyltransferase activity											MetaCyc:ANTHRANILATE-ADENYLYLTRANSFERASE-RXN|RHEA:22412|EC:2.7.7.55|KEGG_REACTION:R00979		molecular_function											owl:Class	
GO:0072675	biolink:NamedThing	osteoclast fusion	The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.	got7fsn_ti							mah	2011-02-22T02:14:34Z						biological_process											owl:Class	
GO:0052722	biolink:NamedThing	fatty acid in-chain hydroxylase activity	Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O.	got7fsn_ti							ai	2011-08-15T01:41:07Z				MetaCyc:RXN-12186|RHEA:45084		molecular_function											owl:Class	
GO:0019060	biolink:NamedThing	intracellular transport of viral protein in host cell	The directed movement of a viral protein within the host cell.	got7fsn_ti	intracellular viral capsid transport|intracellular transport of viral capsid in host cell|intracellular viral protein transport|viral capsid transport in host cell cytoplasm|viral capsid transport in host cell nucleus|nuclear viral capsid transport|cytoplasmic viral capsid transport|intracellular transport of viral capsid protein in host cell|intracellular transport of viral proteins in host cell				This term is for annotation of proteins responsible for the movement of individual viral proteins, rather than the whole viral particle.						GO:0046801|GO:0046743|GO:0046742			biological_process											owl:Class	
GO:0043749	biolink:NamedThing	phenol, water dikinase activity	Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate.	got7fsn_ti	phenylphosphate synthase activity|phenol:water dikinase activity|ATP:phenol:water phosphotransferase activity											EC:2.7.9.-		molecular_function											owl:Class	
GO:0086093	biolink:NamedThing	G protein-coupled acetylcholine receptor signaling pathway involved in heart process	A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart.	got7fsn_ti	muscarinic receptor signaling pathway involved in heart process|G-protein coupled acetylcholine receptor signaling pathway involved in heart process|M2 receptor signaling pathway involved in heart process|G-protein coupled acetylcholine receptor signalling pathway involved in heart process						bf							biological_process											owl:Class	
GO:0031904	biolink:NamedThing	endosome lumen	The volume enclosed by the membrane of an endosome.	got7fsn_ti												NIF_Subcellular:sao1547508851		cellular_component											owl:Class	
GO:0006305	biolink:NamedThing	DNA alkylation	The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0010249	biolink:NamedThing	auxin conjugate metabolic process	The chemical reactions and pathways involving auxin conjugates, a bound form of auxin.	got7fsn_ti	auxin conjugate metabolism													biological_process											owl:Class	
GO:0000031	biolink:NamedThing	mannosylphosphate transferase activity	Catalysis of the transfer of a mannosylphosphate group from one compound to another.	got7fsn_ti														molecular_function											owl:Class	
GO:0090678	biolink:NamedThing	cell dedifferentiation involved in phenotypic switching	A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.	got7fsn_ti							tb	2016-04-28T17:32:40Z						biological_process											owl:Class	
GO:0060266	biolink:NamedThing	negative regulation of respiratory burst involved in inflammatory response	Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	got7fsn_ti	negative regulation of respiratory burst involved in acute inflammatory response													biological_process											owl:Class	
GO:0017044	biolink:NamedThing	melanocyte-stimulating hormone activity	The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates.	got7fsn_ti	alpha-melanophore stimulating hormone activity|melanocyte stimulating hormone activity|alpha-melanocyte stimulating hormone activity													molecular_function											owl:Class	
GO:0061661	biolink:NamedThing	FAT10 ligase activity	Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S --> X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3						dph	2014-11-06T13:53:10Z						molecular_function											owl:Class	
GO:0019775	biolink:NamedThing	FAT10 transferase activity	Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y --> Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages.	got7fsn_ti	FAT10 conjugating enzyme activity													molecular_function											owl:Class	
GO:0045133	biolink:NamedThing	2,3-dihydroxybenzoate 3,4-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).	got7fsn_ti	2,3-dihydroxybenzoate oxygenase activity|o-pyrocatechuate oxygenase activity|2,3-dihydroxybenzoate 1,2-dioxygenase activity|2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)|2,3-dihydroxybenzoic oxygenase activity											RHEA:18477|EC:1.13.11.14|KEGG_REACTION:R01507|MetaCyc:1.13.11.14-RXN		molecular_function											owl:Class	
GO:0047762	biolink:NamedThing	caffeate 3,4-dioxygenase activity	Catalysis of the reaction: trans-caffeate + O(2) = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+).	got7fsn_ti	3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing)											MetaCyc:CAFFEATE-34-DIOXYGENASE-RXN|EC:1.13.11.22|KEGG_REACTION:R03365|RHEA:22216		molecular_function											owl:Class	
GO:0071944	biolink:NamedThing	cell periphery	The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.	got7fsn_ti							mah	2010-10-04T01:51:47Z						cellular_component											owl:Class	
GO:0044572	biolink:NamedThing	[4Fe-4S] cluster assembly	The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.	got7fsn_ti	4Fe-4S cluster assembly|[4Fe-4S] cluster biosynthetic process						jl	2012-04-18T03:19:23Z						biological_process											owl:Class	
GO:0047064	biolink:NamedThing	sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity	Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H(2)O.	got7fsn_ti	sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific)|sulochrin oxidase activity											RHEA:24092|MetaCyc:1.10.3.7-RXN|EC:1.21.3.4|KEGG_REACTION:R00060		molecular_function											owl:Class	
GO:0001637	biolink:NamedThing	G protein-coupled chemoattractant receptor activity	Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G-protein chemoattractant receptor activity|G-protein coupled chemoattractant receptor activity|G protein chemoattractant receptor activity													molecular_function											owl:Class	
GO:0001995	biolink:NamedThing	norepinephrine-epinephrine catabolic process in blood stream	The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.	got7fsn_ti	noradrenaline-adrenalin catabolic process in blood stream													biological_process											owl:Class	
GO:0042419	biolink:NamedThing	epinephrine catabolic process	The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	got7fsn_ti	epinephrine breakdown|epinephrine catabolism|adrenaline catabolism|epinephrine degradation|adrenaline catabolic process													biological_process											owl:Class	
GO:0044295	biolink:NamedThing	axonal growth cone	The migrating motile tip of a growing nerve cell axon.	got7fsn_ti	axon growth cone						jl	2010-02-04T03:57:16Z				NIF_Subcellular:sao1594955670|NIF_Subcellular:sao203987954		cellular_component											owl:Class	
GO:0047682	biolink:NamedThing	aryl-alcohol oxidase activity	Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2.	got7fsn_ti	veratryl alcohol oxidase activity|aryl alcohol oxidase activity|aryl-alcohol:oxygen oxidoreductase activity|arom. alcohol oxidase activity											MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN|RHEA:17541|EC:1.1.3.7		molecular_function											owl:Class	
GO:1990029	biolink:NamedThing	vasomotion	The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm.	got7fsn_ti							tb	2013-02-06T22:30:21Z						biological_process											owl:Class	
GO:0001042	biolink:NamedThing	RNA polymerase I core binding	Binding to a RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.	got7fsn_ti							krc	2010-09-23T01:39:23Z						molecular_function											owl:Class	
GO:0090617	biolink:NamedThing	mitochondrial mRNA 5'-end processing	Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome.	got7fsn_ti							tb	2014-10-24T12:45:08Z						biological_process											owl:Class	
GO:0120323	biolink:NamedThing	lipid ubiquitination	The process in which one or more ubiquitin groups are added to a lipid.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21857					krc	2021-07-20T18:58:34Z						biological_process											owl:Class	
GO:0120322	biolink:NamedThing	lipid modification by small protein conjugation	A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21857					krc	2021-07-20T18:53:03Z						biological_process											owl:Class	
GO:0033976	biolink:NamedThing	2-haloacid dehalogenase (configuration-inverting) activity	Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.	got7fsn_ti	2-haloalkanoic acid dehalogenase activity|DL-DEXi|DL-2-haloacid halidohydrolase (inversion of configuration) activity|DL-2-haloacid dehalogenase activity|DL-2-haloacid dehalogenase (inversion of configuration) activity|2-haloalkanoid acid halidohydrolase activity											MetaCyc:3.8.1.10-RXN		molecular_function											owl:Class	
GO:0018634	biolink:NamedThing	alpha-pinene monooxygenase [NADH] activity	Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide.	got7fsn_ti												UM-BBD_reactionID:r0742|EC:1.14.13.-		molecular_function											owl:Class	
GO:0097473	biolink:NamedThing	retinal rod cell apoptotic process	Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.	got7fsn_ti	rod photoreceptor apoptotic process						pr	2013-03-21T09:44:45Z						biological_process											owl:Class	
GO:1990009	biolink:NamedThing	retinal cell apoptotic process	Any apoptotic process in a retinal cell.	got7fsn_ti	induction of retinal programmed cell death						pr	2012-12-12T10:15:08Z			GO:0046674			biological_process											owl:Class	
GO:0034684	biolink:NamedThing	integrin alphav-beta5 complex	An integrin complex that comprises one alphav subunit and one beta5 subunit.	got7fsn_ti	alphav-beta5 integrin complex|ITGAV-ITGB5 complex													cellular_component											owl:Class	
GO:0061543	biolink:NamedThing	3-demethylubiquinol-6 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-6 = S-adenosyl-L-homocysteine + ubiquinol-6.	got7fsn_ti							dph	2013-06-25T08:05:14Z						molecular_function											owl:Class	
GO:0106094	biolink:NamedThing	nuclear membrane microtubule tethering complex	A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules.	got7fsn_ti		nuclear membrane microtubule tethering complex					hjd	2018-02-02T18:58:35Z						cellular_component											owl:Class	
GO:0106083	biolink:NamedThing	nuclear membrane protein complex	Any protein complex that is part of the nuclear membrane.	got7fsn_ti							hjd	2018-01-05T19:51:26Z						cellular_component											owl:Class	
GO:0050248	biolink:NamedThing	Renilla-luciferin 2-monooxygenase activity	Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light.	got7fsn_ti	Renilla-type luciferase activity|aequorin activity|luciferase activity|Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating)|luciferase (Renilla luciferin)											MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN|RHEA:14765|EC:1.13.12.5		molecular_function											owl:Class	
GO:0033999	biolink:NamedThing	chondroitin B lyase activity	Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.	got7fsn_ti	ChnB|chonB|chondroitinase B activity|dermatan sulfate lyase activity											MetaCyc:4.2.2.19-RXN|EC:4.2.2.19		molecular_function											owl:Class	
GO:0060420	biolink:NamedThing	regulation of heart growth	Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.	got7fsn_ti														biological_process											owl:Class	
GO:0003072	biolink:NamedThing	renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure	The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature.	got7fsn_ti	renal regulation of systemic arterial blood pressure by control of peripheral vascular resistence|regulation of systemic arterial blood pressure by renal control of peripheral vascular resistence													biological_process											owl:Class	
GO:0036416	biolink:NamedThing	tRNA stabilization	Prevention of degradation of tRNA molecules.	got7fsn_ti							bf	2013-08-22T15:41:26Z						biological_process											owl:Class	
GO:0036415	biolink:NamedThing	regulation of tRNA stability	Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs.	got7fsn_ti							bf	2013-08-22T15:22:13Z						biological_process											owl:Class	
GO:0052799	biolink:NamedThing	coenzyme F420-dependent bicyclic nitroimidazole catabolic process	The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates.	got7fsn_ti	coenzyme F420-dependent nitroimidazole catabolism|coenzyme F420-dependent nitroimidazole reduction|coenzyme F420-dependent nitroreductase activity|coenzyme F420-dependent nitroimidazole breakdown													biological_process											owl:Class	
GO:0009227	biolink:NamedThing	nucleotide-sugar catabolic process	The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti	nucleotide-sugar breakdown|nucleotide-sugar catabolism|nucleotide-sugar degradation													biological_process											owl:Class	
GO:0061069	biolink:NamedThing	male urethra development	The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.	got7fsn_ti							dph	2010-03-12T08:28:19Z						biological_process											owl:Class	
GO:0085034	biolink:NamedThing	suppression by symbiont of host I-kappaB kinase/NF-kappaB cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade						jl	2010-07-27T03:32:44Z						biological_process											owl:Class	
GO:0039552	biolink:NamedThing	RIG-I binding	Binding to RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA.	got7fsn_ti	DDX58 binding|DDX58/RIG-I binding						bf	2012-01-19T02:14:20Z						molecular_function											owl:Class	
GO:0033546	biolink:NamedThing	myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate	The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further.	got7fsn_ti	phytate biosynthesis, via inositol 1,3,4-trisphosphate|phytate biosynthetic process, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate biosynthesis, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate synthesis, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate formation, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate anabolism, via inositol 1,3,4-trisphosphate											MetaCyc:PWY-6554		biological_process											owl:Class	
GO:0033337	biolink:NamedThing	dorsal fin development	The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0102352	biolink:NamedThing	phosphatidate kinase activity	Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate.	got7fsn_ti												MetaCyc:RXN-13336		molecular_function											owl:Class	
GO:0060155	biolink:NamedThing	platelet dense granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.	got7fsn_ti	bull's eye body organization and biogenesis|platelet dense body organization and biogenesis|platelet dense granule organisation|platelet dense granule organization and biogenesis													biological_process											owl:Class	
GO:1990617	biolink:NamedThing	CHOP-ATF4 complex	A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits.	got7fsn_ti	GADD153-ATF4 complex|CHOP-CREB-2 complex|CHOP/ATF4 complex|ATF4-CHOP heterodimer|CHOP-ATF4 heterodimer						bf	2015-01-22T11:29:51Z						cellular_component											owl:Class	
GO:0045547	biolink:NamedThing	dehydrodolichyl diphosphate synthase activity	Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0001905	biolink:NamedThing	activation of membrane attack complex	The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis.	got7fsn_ti	activation of the terminal complement cascade|activation of MAC|activation of terminal complement complex|activation of TCC|MAC assembly|membrane attack complex assembly|membrane attack complex formation|MAC formation													biological_process											owl:Class	
GO:0075042	biolink:NamedThing	negative regulation of establishment of turgor in appressorium	Any process that stops, prevents, or reduces the frequency, rate or extent of turgor formation in the symbiont appressorium.	got7fsn_ti														biological_process											owl:Class	
GO:0052815	biolink:NamedThing	medium-chain acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length.	got7fsn_ti	medium-chain hydrolase activity|medium-chain-acyl-CoA hydrolase activity|medium-chain acyl-thioester hydrolase activity|medium-chain acyl coenzyme A hydrolase activity						ai	2011-10-25T05:26:29Z						molecular_function											owl:Class	
GO:0035609	biolink:NamedThing	C-terminal protein deglutamylation	The removal of a C-terminal, gene-encoded glutamate residue from a protein.	got7fsn_ti	protein primary sequence deglutamylation						bf	2010-11-18T01:06:00Z						biological_process											owl:Class	
GO:0072345	biolink:NamedThing	NAADP-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts.	got7fsn_ti							mah	2010-11-10T01:03:35Z				Reactome:R-HSA-2685505		molecular_function											owl:Class	
GO:0015278	biolink:NamedThing	calcium-release channel activity	Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	intracellular ligand-gated calcium channel activity										GO:0005218			molecular_function											owl:Class	
GO:0000773	biolink:NamedThing	phosphatidyl-N-methylethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.	got7fsn_ti	phosphatidyl-N-methylethanolamine methyltransferase activity|phospholipid methyltransferase activity|PLMT|methyltransferase II|phosphatidylmonomethylethanolamine methyltransferase activity|phosphatidylethanolamine methyltransferase I|S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase activity|phosphatidyl-N-monomethylethanolamine methyltransferase activity											MetaCyc:2.1.1.71-RXN|EC:2.1.1.71|RHEA:32735		molecular_function											owl:Class	
GO:0070160	biolink:NamedThing	tight junction	A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.	got7fsn_ti	occluding cell junction|occluding junction											Wikipedia:Tight_junction		cellular_component											owl:Class	
GO:0031808	biolink:NamedThing	H2 histamine receptor binding	Binding to a H2 histamine receptor.	got7fsn_ti	H2 histamine receptor ligand													molecular_function											owl:Class	
GO:1990875	biolink:NamedThing	nucleoplasmic side of nuclear pore	The side of the nuclear pore complex (NPC) that faces the nucleoplasm.	got7fsn_ti	nucleoplasmic side of nucleopore|nucleoplasmic side of NPC|nucleoplasmic side of nuclear pore complex						sl	2015-10-01T21:32:22Z						cellular_component											owl:Class	
GO:0043336	biolink:NamedThing	site-specific telomere resolvase activity	Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases.	got7fsn_ti	ResT|TelN				Note that while this enzyme uses a similar reaction chemistry to topoisomerases and site-specific recombinases, it performs a unique reaction. Topoisomerases promote breakage and reunion of either one or two DNA strands to alter the topological state of a DNA molecule. Site-specific recombinases perform a more complex reaction in which four strands are broken and subsequently joined to a different DNA duplex, resulting in the production of a recombinant product. The telomere resolvases on the other hand, must break two phosphodiester bonds in a single DNA duplex (one on each strand) and join each end with the opposite DNA strand to form covalently closed hairpin telomeres.									molecular_function											owl:Class	
GO:0097135	biolink:NamedThing	cyclin E2-CDK2 complex	A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:59:57Z						cellular_component											owl:Class	
GO:0071487	biolink:NamedThing	cellular response to low light intensity stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.	got7fsn_ti							mah	2009-12-18T02:13:29Z						biological_process											owl:Class	
GO:0006584	biolink:NamedThing	catecholamine metabolic process	The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	got7fsn_ti	catecholamine metabolism													biological_process											owl:Class	
GO:0008386	biolink:NamedThing	cholesterol monooxygenase (side-chain-cleaving) activity	Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.	got7fsn_ti	cytochrome P-450(scc) activity|steroid 20-22 desmolase activity|cholesterol C20-22 desmolase activity|cytochrome p450scc|cholesterol side-chain-cleaving enzyme activity|cholesterol 20-22-desmolase activity|C27-side chain cleavage enzyme|enzymes, cholesterol side-chain-cleaving|cholesterol side-chain cleavage enzyme activity|Cyp11a1|cholesterol C(20-22) desmolase activity|cytochrome P-450scc|steroid 20-22-lyase activity|cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)|desmolase, steroid 20-22|cholesterol desmolase activity|cytochrome p450(scc) activity											RHEA:35739|MetaCyc:1.14.15.6-RXN|EC:1.14.15.6|Reactome:R-HSA-193065|Reactome:R-HSA-193054|Reactome:R-HSA-193101		molecular_function											owl:Class	
GO:1990084	biolink:NamedThing	DnaA-Dps complex	A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps.	got7fsn_ti							bhm	2013-04-30T11:50:17Z						cellular_component											owl:Class	
GO:1990078	biolink:NamedThing	replication inhibiting complex	A protein complex that inhibits multiple events of replication initiation during one replication cycle.	got7fsn_ti							bhm	2013-04-26T13:07:03Z						cellular_component											owl:Class	
GO:0090404	biolink:NamedThing	pollen tube tip	The region at growing end of the pollen tube cell, where polarized growth occurs.	got7fsn_ti							tb	2011-01-10T10:25:58Z						cellular_component											owl:Class	
GO:0035637	biolink:NamedThing	multicellular organismal signaling	The transfer of information occurring at the level of a multicellular organism.	got7fsn_ti	multicellular organismal signalling						bf	2011-01-14T10:13:50Z						biological_process											owl:Class	
GO:0102749	biolink:NamedThing	dihydrogeranylgeranyl-chlorophyll a reductase activity	Catalysis of the reaction: H+ + dihydrogeranylgeranyl-chlorophyll a + NADPH = tetrahydrogeranylgeranyl-chlorophyll a + NADP.	got7fsn_ti												MetaCyc:RXN-7665		molecular_function											owl:Class	
GO:0061752	biolink:NamedThing	telomeric repeat-containing RNA binding	Binding to long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats.	got7fsn_ti	TERRA binding						dph	2015-11-13T07:55:06Z						molecular_function											owl:Class	
GO:0034885	biolink:NamedThing	gamma-N-formylaminovinylacetate hydrolase activity	Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH.	got7fsn_ti												UM-BBD_reactionID:r1350		molecular_function											owl:Class	
GO:1990396	biolink:NamedThing	single-strand break repair via homologous recombination	The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.	got7fsn_ti							bhm	2014-06-09T10:47:04Z						biological_process											owl:Class	
GO:0000725	biolink:NamedThing	recombinational repair	A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.	got7fsn_ti												Wikipedia:Recombinational_repair		biological_process											owl:Class	
GO:0044042	biolink:NamedThing	glucan metabolic process	The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.	got7fsn_ti	glucan metabolism													biological_process											owl:Class	
GO:0004712	biolink:NamedThing	protein serine/threonine/tyrosine kinase activity	Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.	got7fsn_ti	dual-specificity kinase activity|dual-specificity protein kinase|protein threonine/tyrosine kinase activity											RHEA:10596|RHEA:46608|Reactome:R-HSA-6802922|Reactome:R-HSA-6802927|EC:2.7.12.1|Reactome:R-HSA-6802918|Reactome:R-HSA-6802910|Reactome:R-HSA-6802921|Reactome:R-HSA-6802916|RHEA:17989|Reactome:R-HSA-6802941|Reactome:R-HSA-6802924|Reactome:R-HSA-5674373|Reactome:R-HSA-9656212|Reactome:R-HSA-5672969		molecular_function											owl:Class	
GO:0031962	biolink:NamedThing	mineralocorticoid receptor binding	Binding to a mineralocorticoid receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0061057	biolink:NamedThing	peptidoglycan recognition protein signaling pathway	A series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.	got7fsn_ti	Imd signaling pathway|immune deficiency pathway|Imd signalling pathway|PGRP signaling pathway|immune deficiency signaling pathway						dph	2010-03-02T12:20:10Z						biological_process											owl:Class	
GO:0140282	biolink:NamedThing	carbon-nitrogen ligase activity on lipid II	Catalysis of the reaction: L-glutamine + lipid II + ATP + H2O = L-glutamate + beta-D-GlcNAc(1->4)-Mur2Ac(oyl-L-Ala-D-isoGln-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol + ADP + phosphate.	got7fsn_ti	L-glutamate--lipid II transaminase activity|carbon-nitrogen ligase activity on lipid II|undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl pentapeptide amidotransferase (glutamine-hydrolyzing) activity	https://github.com/geneontology/go-ontology/issues/16422					pg	2018-10-08T19:12:57Z				RHEA:57928|EC:6.3.5.13		molecular_function											owl:Class	
GO:0051509	biolink:NamedThing	tomatidine UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + tomatidine = UDP + O-glucosyl-tomatidine.	got7fsn_ti														molecular_function											owl:Class	
GO:0044567	biolink:NamedThing	primary cell wall cellulose synthase complex	A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein.	got7fsn_ti	primary cell wall CESA complex|primary cell-wall cellulose synthase complex						jl	2012-04-18T12:24:16Z						cellular_component											owl:Class	
GO:0071035	biolink:NamedThing	nuclear polyadenylation-dependent rRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.	got7fsn_ti	nuclear poly(A)-dependent rRNA catabolic process						krc	2009-07-29T12:42:39Z						biological_process											owl:Class	
GO:0046152	biolink:NamedThing	ommochrome metabolic process	The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.	got7fsn_ti	ommochrome metabolism													biological_process											owl:Class	
GO:0102821	biolink:NamedThing	bixin methyltransferase activity	Catalysis of the reaction: bixin + S-adenosyl-L-methionine  <=> bixin dimethyl ester + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-8239		molecular_function											owl:Class	
GO:0021911	biolink:NamedThing	retinoic acid metabolic process in spinal cord anterior-posterior patterning	The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.	got7fsn_ti	retinoic acid metabolism in spinal cord anterior-posterior patterning													biological_process											owl:Class	
GO:0042573	biolink:NamedThing	retinoic acid metabolic process	The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.	got7fsn_ti	retinoic acid metabolism|vitamin A1 acid metabolic process|vitamin A1 acid metabolism													biological_process											owl:Class	
GO:0000730	biolink:NamedThing	DNA recombinase assembly	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA.	got7fsn_ti	Rad51 nucleoprotein filament formation													biological_process											owl:Class	
GO:0106379	biolink:NamedThing	8-oxo-(d)RTP hydrolase activity	Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+.	got7fsn_ti							hjd	2021-05-26T14:36:55Z						molecular_function											owl:Class	
GO:0046910	biolink:NamedThing	pectinesterase inhibitor activity	Binds to and stops, prevents or reduces the activity of pectinesterase.	got7fsn_ti					See also the molecular function term 'pectinesterase activity ; GO:0030599'.									molecular_function											owl:Class	
GO:0042802	biolink:NamedThing	identical protein binding	Binding to an identical protein or proteins.	got7fsn_ti	protein homopolymerization|isoform-specific homophilic binding													molecular_function											owl:Class	
GO:0007274	biolink:NamedThing	neuromuscular synaptic transmission	The process of synaptic transmission from a neuron to a muscle, across a synapse.	got7fsn_ti														biological_process											owl:Class	
GO:0033668	biolink:NamedThing	negative regulation by symbiont of host apoptotic process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	downregulation by organism of host apoptotic programmed cell death|inhibition by organism of host apoptotic programmed cell death|negative regulation by symbiont of host apoptosis|down-regulation by organism of host apoptotic programmed cell death|down regulation by organism of host apoptotic programmed cell death				Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of apoptosis ; GO:0043066'.									biological_process											owl:Class	
GO:0097492	biolink:NamedThing	sympathetic neuron axon guidance	The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.	got7fsn_ti	sympathetic neuron axon growth cone guidance|sympathetic neuron axon chemotaxis|sympathetic neuron axon pathfinding						pr	2013-07-10T11:50:52Z						biological_process											owl:Class	
GO:0030961	biolink:NamedThing	peptidyl-arginine hydroxylation	The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.	got7fsn_ti														biological_process											owl:Class	
GO:0010191	biolink:NamedThing	mucilage metabolic process	The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants.	got7fsn_ti	mucilage metabolism													biological_process											owl:Class	
GO:1990482	biolink:NamedThing	sphingolipid alpha-glucuronosyltransferase activity	Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC.	got7fsn_ti	inositol phosphorylceramide glucuronosyltransferase activity						tb	2014-09-12T22:10:09Z						molecular_function											owl:Class	
GO:0070996	biolink:NamedThing	type 1 melanocortin receptor binding	Binding to a type 1 melanocortin receptor.	got7fsn_ti	type 1 melanocortin receptor ligand						mah	2009-11-03T01:50:53Z						molecular_function											owl:Class	
GO:0004810	biolink:NamedThing	tRNA adenylyltransferase activity	Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1).	got7fsn_ti	tRNA-nucleotidyltransferase activity|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase|transfer ribonucleate adenylyltransferase|transfer ribonucleic acid nucleotidyl transferase|-C-C-A pyrophosphorylase|CCA-adding enzyme activity|ATP:tRNA adenylyltransferase activity|ATP(CTP)-tRNA nucleotidyltransferase|transfer RNA adenylyltransferase|ribonucleic cytidylyltransferase|transfer ribonucleic adenylyl (cytidylyl) transferase|transfer ribonucleate cytidylyltransferase|transfer-RNA nucleotidyltransferase|transfer ribonucleate adenyltransferase activity|ATP (CTP):tRNA nucleotidyltransferase|tRNA adenylyl(cytidylyl)transferase|tRNA CCA-diphosphorylase activity|tRNA CCA-pyrophosphorylase activity|transfer ribonucleate nucleotidyltransferase|CTP(ATP):tRNA nucleotidyltransferase											MetaCyc:TRNA-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.72		molecular_function											owl:Class	
GO:1990817	biolink:NamedThing	RNA adenylyltransferase activity	Catalysis of the template-independent extension of the 3'- end of an RNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA, or oligo(A) bearing a 3'-OH terminal group.	got7fsn_ti							vw	2015-07-31T09:38:31Z						molecular_function											owl:Class	
GO:0001715	biolink:NamedThing	ectodermal cell fate specification	The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	ectoderm cell fate specification													biological_process											owl:Class	
GO:0004851	biolink:NamedThing	uroporphyrin-III C-methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2.	got7fsn_ti	SirA|adenosylmethionine-uroporphyrinogen III methyltransferase activity|urogen III methylase activity|SUMT activity|uroporphyrinogen-III C-methyltransferase activity|uroporphyrinogen-III methylase activity|CysG|S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase activity|uroporphyrinogen methyltransferase activity|uroporphyrinogen-III methyltransferase activity|uroporphyrinogen III methylase activity|CobA|S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase activity|S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase activity											EC:2.1.1.107|MetaCyc:UROPORIIIMETHYLTRANSA-RXN|RHEA:32459		molecular_function											owl:Class	
GO:0047980	biolink:NamedThing	hippurate hydrolase activity	Catalysis of the reaction: N-benzoylglycine + H(2)O = benzoate + glycine.	got7fsn_ti	benzoylglycine amidohydrolase activity|hippuricase activity|N-benzoylamino-acid amidohydrolase activity											MetaCyc:HIPPURATE-HYDROLASE-RXN|RHEA:10424|EC:3.5.1.32|KEGG_REACTION:R01424		molecular_function											owl:Class	
GO:0031363	biolink:NamedThing	N-terminal protein amino acid deamination	The removal of an amino group from the N-terminal amino acid residue of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0060106	biolink:NamedThing	cortical layer of collagen and cuticulin-based cuticle extracellular matrix	The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans.	got7fsn_ti														cellular_component											owl:Class	
GO:0010784	biolink:NamedThing	proboscis morphogenesis, clypeo-labral disc-derived	The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0018035	biolink:NamedThing	C-terminal peptidyl-arginine amidation	The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0082		biological_process											owl:Class	
GO:0050258	biolink:NamedThing	riboflavinase activity	Catalysis of the reaction: H(2)O + H(+) + riboflavin = D-ribitol + lumichrome.	got7fsn_ti	riboflavin hydrolase activity											KEGG_REACTION:R01732|EC:3.5.99.1|MetaCyc:RIBOFLAVINASE-RXN|RHEA:11408		molecular_function											owl:Class	
GO:0001998	biolink:NamedThing	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure	The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream.	got7fsn_ti	angiotensin mediated vasoconstriction during blood pressure regulation|angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure|angiotensin mediated vasoconstriction during blood pressure control|angiotensin mediated vasoconstriction during control of blood pressure													biological_process											owl:Class	
GO:0050136	biolink:NamedThing	NADH dehydrogenase (quinone) activity	Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.	got7fsn_ti	NADH-quinone oxidoreductase activity|reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase activity|D-diaphorase activity|NADH:(quinone-acceptor) oxidoreductase activity|DPNH-menadione reductase activity											RHEA:46160|MetaCyc:NADH-DEHYDROGENASE-QUINONE-RXN|EC:1.6.5.11		molecular_function											owl:Class	
GO:0039523	biolink:NamedThing	suppression by virus of host RNA polymerase II activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host RNA polymerase II activity.	got7fsn_ti	inhibition of host RNA polymerase II activity by virus|negative regulation by virus of host RNA polymerase II activity|inhibition of host RNA polymerase II by virus						bf	2011-06-22T04:38:59Z				VZ:905		biological_process											owl:Class	
GO:0010205	biolink:NamedThing	photoinhibition	The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II.	got7fsn_ti	photosystem II inhibition											Wikipedia:Photoinhibition		biological_process											owl:Class	
GO:0052896	biolink:NamedThing	spermidine oxidase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: H(2)O + O(2) + spermidine = 1,3-diaminopropane + 4-aminobutanal + H(2)O(2).	got7fsn_ti	polyamine oxidase (propane-1,3-diamine-forming) activity|spermidine:(acceptor) oxidoreductase activity											MetaCyc:RXN-10747|RHEA:25820|KEGG_REACTION:R01914|EC:1.5.3.14		molecular_function											owl:Class	
GO:1903011	biolink:NamedThing	negative regulation of bone development	Any process that stops, prevents or reduces the frequency, rate or extent of bone development.	got7fsn_ti	down-regulation of bone development|downregulation of bone development|inhibition of bone development|down regulation of bone development						mr	2014-05-13T22:42:00Z						biological_process											owl:Class	
GO:1903010	biolink:NamedThing	regulation of bone development	Any process that modulates the frequency, rate or extent of bone development.	got7fsn_ti							mr	2014-05-13T22:41:53Z						biological_process											owl:Class	
GO:0060503	biolink:NamedThing	bud dilation involved in lung branching	The process in which a bud in the lung increases radially.	got7fsn_ti	bud expansion													biological_process											owl:Class	
GO:0035401	biolink:NamedThing	histone kinase activity (H3-Y41 specific)	Catalysis of the transfer of a phosphate group to the tyrosine-41 residue of histone H3.	got7fsn_ti	histone-tyrosine kinase activity (H3-Y41 specific)|histone tyrosine kinase activity (H3-Y41 specific)						bf	2010-03-24T10:01:14Z						molecular_function											owl:Class	
GO:0006169	biolink:NamedThing	adenosine salvage	Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis.	got7fsn_ti	adenine, hypoxanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0046086	biolink:NamedThing	adenosine biosynthetic process	The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.	got7fsn_ti	adenosine biosynthesis|adenosine formation|adenosine anabolism|adenosine synthesis													biological_process											owl:Class	
GO:1990572	biolink:NamedThing	TERT-RMRP complex	A ribonucleoprotein complex that has RNA-directed RNA polymerase (RdRP) activity, and is composed of telomerase reverse transcriptase (TERT) and the non-coding RNA component of mitochondrial RNA processing endoribonuclease (RMRP).	got7fsn_ti	telomerase reverse transcriptase:RMRP RNA complex						bf	2014-12-02T11:29:12Z						cellular_component											owl:Class	
GO:0097313	biolink:NamedThing	bacterial biofilm matrix surface	The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.	got7fsn_ti							pr	2012-05-24T11:25:47Z						cellular_component											owl:Class	
GO:1990329	biolink:NamedThing	IscS-TusA complex	A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.	got7fsn_ti							bhm	2014-03-17T10:00:47Z						cellular_component											owl:Class	
GO:1990221	biolink:NamedThing	L-cysteine desulfurase complex	A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes. In E. coli it consists of a SufS dimer.	got7fsn_ti	SufS complex|NIFS|IscS|NifS						bhm	2013-10-11T15:36:34Z						cellular_component											owl:Class	
GO:0051006	biolink:NamedThing	positive regulation of lipoprotein lipase activity	Any process that activates or increases the activity of the enzyme lipoprotein lipase.	got7fsn_ti	stimulation of lipoprotein lipase activity|up-regulation of lipoprotein lipase activity|up regulation of lipoprotein lipase activity|upregulation of lipoprotein lipase activity|activation of lipoprotein lipase activity													biological_process											owl:Class	
GO:0061365	biolink:NamedThing	positive regulation of triglyceride lipase activity	Any process that increases the activity of triglyceride lipase.	got7fsn_ti	positive regulation of TAG activity						dph	2010-10-15T08:27:22Z						biological_process											owl:Class	
GO:0047809	biolink:NamedThing	D-2-hydroxy-acid dehydrogenase activity	Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate.	got7fsn_ti	2-hydroxy acid dehydrogenase activity|(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity											KEGG_REACTION:R00297|RHEA:15089|EC:1.1.99.6|MetaCyc:D-2-HYDROXY-ACID-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0072571	biolink:NamedThing	mono-ADP-D-ribose binding	Binding to monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.	got7fsn_ti	mono-ADP-ribose binding|mADPr binding						mah	2011-01-31T02:39:12Z						molecular_function											owl:Class	
GO:0072570	biolink:NamedThing	ADP-D-ribose binding	Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.	got7fsn_ti	ADP-ribose binding						mah	2011-01-31T02:37:30Z						molecular_function											owl:Class	
GO:0031145	biolink:NamedThing	anaphase-promoting complex-dependent catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.	got7fsn_ti	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|APC-dependent proteasomal ubiquitin-dependent protein catabolism|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein breakdown|cyclin catabolic process|negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation|cyclin degradation|APC-dependent proteasomal ubiquitin-dependent protein catabolic process|cyclin catabolism|cyclin breakdown|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolism|degradation of cyclin|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein degradation										GO:0008054			biological_process											owl:Class	
GO:0036528	biolink:NamedThing	peptidyl-lysine deglycation	The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.	got7fsn_ti	deglycation of N-acetyllysine						bf	2016-08-04T10:37:12Z						biological_process											owl:Class	
GO:0047656	biolink:NamedThing	alpha,alpha-trehalose phosphorylase activity	Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.	got7fsn_ti	alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase activity|trehalose phosphorylase|a,a-trehalose phosphorylase activity											MetaCyc:ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN|RHEA:23512|EC:2.4.1.64		molecular_function											owl:Class	
GO:0047394	biolink:NamedThing	glycerophosphoinositol inositolphosphodiesterase activity	Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol.	got7fsn_ti	1,2-cyclic-inositol-phosphate phosphodiesterase activity|inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity|D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase activity|D-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity|1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity|D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity|1-(sn-glycero-3-phospho)-1D-myo-inositol inositolphosphohydrolase activity											RHEA:14033|EC:3.1.4.43|MetaCyc:3.1.4.43-RXN		molecular_function											owl:Class	
GO:0070733	biolink:NamedThing	protein adenylyltransferase activity	Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to specific residues of target proteins.	got7fsn_ti	AMPylator|adenosine monophosphate-protein transferase activity						mah	2009-06-18T01:09:15Z				EC:2.7.7.n1		molecular_function											owl:Class	
GO:0008355	biolink:NamedThing	olfactory learning	Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.	got7fsn_ti														biological_process											owl:Class	
GO:0009769	biolink:NamedThing	photosynthesis, light harvesting in photosystem II	After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.	got7fsn_ti														biological_process											owl:Class	
GO:0020020	biolink:NamedThing	food vacuole	Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.	got7fsn_ti	digestive vacuole										GO:0005772			cellular_component											owl:Class	
GO:0001003	biolink:NamedThing	RNA polymerase III type 2 promoter sequence-specific DNA binding	Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.	got7fsn_ti	RNA polymerase III type 2 promoter DNA binding						krc	2010-08-18T05:51:18Z			GO:0001031			molecular_function											owl:Class	
GO:0032370	biolink:NamedThing	positive regulation of lipid transport	Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	stimulation of lipid transport|activation of lipid transport|up regulation of lipid transport|upregulation of lipid transport|up-regulation of lipid transport													biological_process											owl:Class	
GO:0030131	biolink:NamedThing	clathrin adaptor complex	A membrane coat adaptor complex that links clathrin to a membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0020006	biolink:NamedThing	symbiont-containing vacuolar membrane network	Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm.	got7fsn_ti	parasitophorous vacuolar membrane network|tubulovesicular network|symbiont-containing vacuole membrane network													cellular_component											owl:Class	
GO:0120267	biolink:NamedThing	pellicular membrane	The portion of the plasma membrane surrounding the pellicle, a structure enclosing some parasite cells such as certain apicomplexa and Euglenozoa. These membranes are associated with an infrastructure of microtubules, microfilaments, and other organelles.	got7fsn_ti	pellicle membrane|pellicular plasma membrane	https://github.com/geneontology/go-ontology/issues/20034			This sub-domain of the plasma membrane excludes the ciliary and ciliary pocket membranes.		krc	2020-09-29T21:08:28Z						cellular_component											owl:Class	
GO:0070497	biolink:NamedThing	6-carboxy-5,6,7,8-tetrahydropterin synthase activity	Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.	got7fsn_ti												MetaCyc:RXN0-5507|EC:4.1.2.50|RHEA:27966		molecular_function											owl:Class	
GO:0048251	biolink:NamedThing	elastic fiber assembly	Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.	got7fsn_ti	elastin fiber assembly|elastic fibre assembly|elastin fibre assembly													biological_process											owl:Class	
GO:0032470	biolink:NamedThing	positive regulation of endoplasmic reticulum calcium ion concentration	Any process that increases the concentration of calcium ions in the endoplasmic reticulum.	got7fsn_ti	elevation of endoplasmic reticulum calcium ion concentration|endoplasmic reticulum calcium ion concentration elevation|elevation of ER calcium ion concentration|elevation of calcium ion concentration in endoplasmic reticulum													biological_process											owl:Class	
GO:0051236	biolink:NamedThing	establishment of RNA localization	The directed movement of RNA to a specific location.	got7fsn_ti	RNA recruitment|establishment of RNA localisation|RNA positioning													biological_process											owl:Class	
GO:0070649	biolink:NamedThing	formin-nucleated actin cable assembly	The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.	got7fsn_ti	formin-nucleated actin cable formation						mah	2009-05-12T02:14:36Z						biological_process											owl:Class	
GO:0034657	biolink:NamedThing	GID complex	A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p.	got7fsn_ti														cellular_component											owl:Class	
GO:0005150	biolink:NamedThing	interleukin-1, type I receptor binding	Binding to a Type I interleukin-1 receptor.	got7fsn_ti	interleukin-1, type I receptor ligand|IL-1 type I													molecular_function											owl:Class	
GO:0035778	biolink:NamedThing	pronephric nephron tubule epithelial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.	got7fsn_ti							bf	2011-04-04T11:07:47Z						biological_process											owl:Class	
GO:0039014	biolink:NamedThing	cell differentiation involved in pronephros development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state.	got7fsn_ti	cell differentiation involved in pronephric kidney development						bf	2010-07-02T09:59:25Z						biological_process											owl:Class	
GO:0016577	biolink:NamedThing	histone demethylation	The modification of histones by removal of methyl groups.	got7fsn_ti														biological_process											owl:Class	
GO:0044740	biolink:NamedThing	negative regulation of sensory perception of pain in other organism	A process that negatively regulates the sensory perception of pain in a different organism.	got7fsn_ti	inhibition of sensory perception of pain in another organism						jl	2012-11-07T13:43:10Z						biological_process											owl:Class	
GO:0047610	biolink:NamedThing	acetylsalicylate deacetylase activity	Catalysis of the reaction: acetylsalicylate + H(2)O = acetate + H(+) + salicylate.	got7fsn_ti	aspirin esterase activity|aspirin hydrolase activity|acetylsalicylate O-acetylhydrolase activity|acetylsalicylic acid esterase activity											RHEA:11752|EC:3.1.1.55|MetaCyc:ACETYLSALICYLATE-DEACETYLASE-RXN|KEGG_REACTION:R02942		molecular_function											owl:Class	
GO:0035081	biolink:NamedThing	induction of programmed cell death by hormones	Any process induced by hormones that directly activates any of the steps required for programmed cell death.	got7fsn_ti														biological_process											owl:Class	
GO:0012502	biolink:NamedThing	induction of programmed cell death	A process which directly activates any of the steps required for programmed cell death.	got7fsn_ti	induction of non-apoptotic programmed cell death|induction of nonapoptotic programmed cell death										GO:0012503			biological_process											owl:Class	
GO:0035518	biolink:NamedThing	histone H2A monoubiquitination	The modification of histone H2A by addition of a single ubiquitin group.	got7fsn_ti							bf	2010-05-04T04:22:09Z						biological_process											owl:Class	
GO:0110155	biolink:NamedThing	NAD-cap decapping	Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.	got7fsn_ti							kmv	2019-07-08T17:27:56Z						biological_process											owl:Class	
GO:0009360	biolink:NamedThing	DNA polymerase III complex	The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork.	got7fsn_ti	DNA polymerase III holoenzyme complex													cellular_component											owl:Class	
GO:0034320	biolink:NamedThing	alcohol O-hexanoyltransferase activity	Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.	got7fsn_ti														molecular_function											owl:Class	
GO:0071182	biolink:NamedThing	MAML3-RBP-Jkappa-ICN4 complex	A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML3-RBP-Jkappa-Notch4 complex						mah	2009-11-23T02:52:35Z						cellular_component											owl:Class	
GO:0038100	biolink:NamedThing	nodal binding	Binding to a nodal protein, a member of the transforming growth factor-beta superfamily.	got7fsn_ti							bf	2012-02-17T11:19:08Z						molecular_function											owl:Class	
GO:0031515	biolink:NamedThing	tRNA (m1A) methyltransferase complex	A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.	got7fsn_ti														cellular_component											owl:Class	
GO:0043527	biolink:NamedThing	tRNA methyltransferase complex	A multimeric protein complex involved in the methylation of specific nucleotides in tRNA.	got7fsn_ti														cellular_component											owl:Class	
GO:0060458	biolink:NamedThing	right lung development	The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.	got7fsn_ti	right pulmonary development													biological_process											owl:Class	
GO:0010038	biolink:NamedThing	response to metal ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.	got7fsn_ti	heavy metal sensitivity/resistance|response to heavy metal|response to metal													biological_process											owl:Class	
GO:0071610	biolink:NamedThing	chemokine (C-C motif) ligand 1 production	The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CCL1 production|TCA-3 production|T cell activation 3 production						mah	2010-02-05T04:35:00Z						biological_process											owl:Class	
GO:0018626	biolink:NamedThing	2-chlorobenzoate 1,2-dioxygenase activity	Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.	got7fsn_ti	2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating)|2-halobenzoate 1,2-dioxygenase activity											EC:1.14.12.13|UM-BBD_reactionID:r0632|RHEA:21652|MetaCyc:2-CHLOROBENZOATE-12-DIOXYGENASE-RXN		molecular_function											owl:Class	
GO:0016675	biolink:NamedThing	oxidoreductase activity, acting on a heme group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti	oxidoreductase activity, acting on heme group of donors, other acceptors|oxidoreductase activity, acting on haem group of donors											EC:1.9.-.-		molecular_function											owl:Class	
GO:0052639	biolink:NamedThing	salicylic acid glucosyltransferase (ester-forming) activity	Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP.	got7fsn_ti	UDP:glucose:SA glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase activity|UDP:glucose:salicylic acid glucosyltransferase (ester-forming) activity|UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (ester-forming) activity|UDP:glucose:salicylate glucosyltransferase (ester-forming) activity											RHEA:62316|MetaCyc:RXN-11659		molecular_function											owl:Class	
GO:0002121	biolink:NamedThing	inter-male aggressive behavior	Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.	got7fsn_ti	inter-male aggression													biological_process											owl:Class	
GO:0048580	biolink:NamedThing	regulation of post-embryonic development	Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0050529	biolink:NamedThing	polyneuridine-aldehyde esterase activity	Catalysis of the reaction: H(2)O + polyneuridine aldehyde = 16-epivellosimine + CO(2) + methanol.	got7fsn_ti	polyneuridine aldehyde esterase activity|polyneuridine aldehyde hydrolase (decarboxylating)|PNAE activity											EC:3.1.1.78|RHEA:17501|KEGG_REACTION:R05825|MetaCyc:3.1.1.78-RXN		molecular_function											owl:Class	
GO:0106321	biolink:NamedThing	S-(hydroxymethyl)glutathione dehydrogenase NADP activity	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+.	got7fsn_ti							hjd	2020-09-23T15:26:27Z				RHEA:19981|EC:1.1.1.284		molecular_function											owl:Class	
GO:0051903	biolink:NamedThing	S-(hydroxymethyl)glutathione dehydrogenase activity	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.	got7fsn_ti	S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity|glutathione-dependent formaldehyde dehydrogenase activity|formic dehydrogenase activity|FDH activity|chi-ADH activity|NAD- and glutathione-dependent formaldehyde dehydrogenase activity|class III alcohol dehydrogenase activity|NAD-dependent formaldehyde dehydrogenase activity|ADH3 activity|NAD-linked formaldehyde dehydrogenase activity|GS-FDH activity|GD-FALDH activity											UM-BBD_reactionID:r1146|MetaCyc:RXN-2962|EC:1.1.1.284|Reactome:R-HSA-5692237|KEGG_REACTION:R07140|KEGG_REACTION:R06983		molecular_function											owl:Class	
GO:1990808	biolink:NamedThing	F-bar domain binding	Binding to an F-BAR domain of a protein, a domain of about 60 residues that occurs in a wide range of cytoskeletal proteins.	got7fsn_ti							vw	2015-07-21T18:43:00Z						molecular_function											owl:Class	
GO:0097220	biolink:NamedThing	simple sieve plate	A sieve plate that contains a single specialized sieve area.	got7fsn_ti					Often located on an end wall of a sieve tube member. Unspecialized sieve areas may occur on other parts of the cell.		pr	2012-01-13T05:46:46Z						cellular_component											owl:Class	
GO:0047084	biolink:NamedThing	methyltetrahydroprotoberberine 14-monooxygenase activity	Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine.	got7fsn_ti	(S)-cis-N-methyltetrahydroberberine 14-monooxygenase activity|(S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase activity|methyltetrahydroprotoberberine 14-hydroxylase activity|(S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating)											RHEA:23684|EC:1.14.14.97|MetaCyc:1.14.13.37-RXN		molecular_function											owl:Class	
GO:0018074	biolink:NamedThing	peptidyl-histidine bromination	The bromination of peptidyl-histidine to form peptidyl-L-bromohistidine; the position of the bromine substitution is unknown.	got7fsn_ti												RESID:AA0173		biological_process											owl:Class	
GO:0003110	biolink:NamedThing	positive regulation of the force of heart contraction by neuronal norepinephrine	The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction.	got7fsn_ti	increased force of heart contraction by neuronal noradrenaline|increased force of heart contraction by neuronal norepinephrine													biological_process											owl:Class	
GO:0071427	biolink:NamedThing	mRNA-containing ribonucleoprotein complex export from nucleus	The directed movement of a ribonucleoprotein complex that contains messenger RNA from the nucleus to the cytoplasm.	got7fsn_ti	mRNA-containing RNP export from nucleus|mRNA-containing ribonucleoprotein complex nucleus export|mRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|mRNA-containing ribonucleoprotein complex export from cell nucleus						mah	2009-12-16T10:13:59Z						biological_process											owl:Class	
GO:0046924	biolink:NamedThing	peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine	The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine.	got7fsn_ti												RESID:AA0340		biological_process											owl:Class	
GO:0097550	biolink:NamedThing	transcription preinitiation complex	A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.	got7fsn_ti	transcription preinitiation complex|PIC|transcriptional pre-initiation complex|transcriptional preinitiation complex|preinitiation complex|DNA-templated transcriptional preinitiation complex						pr	2014-01-22T09:33:44Z						cellular_component											owl:Class	
GO:0103117	biolink:NamedThing	UDP-3-O-acyl-N-acetylglucosamine deacetylase activity	Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate.	got7fsn_ti												EC:3.5.1.108|MetaCyc:UDPACYLGLCNACDEACETYL-RXN|RHEA:25209		molecular_function											owl:Class	
GO:0046863	biolink:NamedThing	ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity	Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate.	got7fsn_ti	rubisco activase activity|ribulose-1,5-bisphosphate carboxylase/oxygenase activase activity|rubisco activator|ribulose-bisphosphate carboxylase activase activity				See also the molecular function term 'ribulose-bisphosphate carboxylase activity ; GO:0016984'.						GO:0018236			molecular_function											owl:Class	
GO:0047921	biolink:NamedThing	aminoglycoside 2'-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H(+). This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.	got7fsn_ti	gentamycin acetyltransferase II|acetyl-CoA:gentamicin-C1a N2'-acetyltransferase activity|acetyl-CoA:gentamycin-C1a N2'-acetyltransferase activity|gentamicin acetyltransferase II activity|gentamicin 2'-N-acetyltransferase activity|gentamycin 2'-N-acetyltransferase activity											RHEA:24516|MetaCyc:GENTAMICIN-2-N-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R03056|EC:2.3.1.59		molecular_function											owl:Class	
GO:0034247	biolink:NamedThing	snoRNA splicing	The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0007341	biolink:NamedThing	penetration of zona pellucida	The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.	got7fsn_ti														biological_process											owl:Class	
GO:0047756	biolink:NamedThing	chondroitin 4-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.	got7fsn_ti	3'-phosphoadenylyl-sulfate:chondroitin 4'-sulfotransferase activity|chondroitin 4-sulphotransferase activity											Reactome:R-HSA-1971483|RHEA:16101|EC:2.8.2.5|MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0070781	biolink:NamedThing	response to biotin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.	got7fsn_ti	response to coenzyme R|response to vitamin B7|response to Bios IIB|response to vitamin H						mah	2009-07-02T02:34:43Z						biological_process											owl:Class	
GO:1990234	biolink:NamedThing	transferase complex	A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).	got7fsn_ti							bhm	2013-11-12T13:20:12Z						cellular_component											owl:Class	
GO:0047007	biolink:NamedThing	pregnan-21-ol dehydrogenase (NAD+) activity	Catalysis of the reaction: NAD(+) + pregnan-21-ol = H(+) + NADH + pregnan-21-al.	got7fsn_ti	21-hydroxysteroid dehydrogenase (NAD+) activity|21-hydroxysteroid:NAD+ 21-oxidoreductase activity											EC:1.1.1.150|RHEA:11448|KEGG_REACTION:R03043|MetaCyc:1.1.1.150-RXN		molecular_function											owl:Class	
GO:0106076	biolink:NamedThing	peptide-lysine-N-succinyltransferase activity	Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide.	got7fsn_ti							hjd	2017-12-15T18:25:16Z						molecular_function											owl:Class	
GO:0106075	biolink:NamedThing	peptide N-succinyltransferase activity	Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide.	got7fsn_ti							hjd	2017-12-15T18:23:58Z						molecular_function											owl:Class	
GO:0018046	biolink:NamedThing	C-terminal peptidyl-methionine amidation	The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0093		biological_process											owl:Class	
GO:0051593	biolink:NamedThing	response to folic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.	got7fsn_ti	cellular response to folate|cellular response to vitamin B9													biological_process											owl:Class	
GO:0060845	biolink:NamedThing	venous endothelial cell fate commitment	The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell.	got7fsn_ti							dph	2009-08-12T10:51:23Z						biological_process											owl:Class	
GO:0060846	biolink:NamedThing	blood vessel endothelial cell fate commitment	The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell.	got7fsn_ti							dph	2009-08-12T10:56:14Z						biological_process											owl:Class	
GO:0075028	biolink:NamedThing	negative regulation of appressorium initiation	Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium initiation.	got7fsn_ti	negative regulation of appressorium initiation on or near host|negative regulation of initiation of appressorium on or near host													biological_process											owl:Class	
GO:0001066	biolink:NamedThing	plastid single subunit type RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti							krc	2010-10-19T03:54:57Z						molecular_function											owl:Class	
GO:0043180	biolink:NamedThing	rhythmic inhibition	Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit.	got7fsn_ti														biological_process											owl:Class	
GO:0106368	biolink:NamedThing	dTTP dependent (deoxy)nucleoside - phosphate kinase activity	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dTTP = a 2'-deoxyribonucleoside 5'-diphosphate + dTDP.	got7fsn_ti							hjd	2021-03-11T20:09:34Z				RHEA:62132		molecular_function											owl:Class	
GO:2000252	biolink:NamedThing	negative regulation of feeding behavior	Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.	got7fsn_ti	negative regulation of behavioural response to food|negative regulation of eating|negative regulation of feeding behaviour|negative regulation of drinking|negative regulation of behavioral response to food						yaf	2010-11-18T11:24:14Z						biological_process											owl:Class	
GO:0060259	biolink:NamedThing	regulation of feeding behavior	Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.	got7fsn_ti	regulation of feeding behaviour													biological_process											owl:Class	
GO:0047913	biolink:NamedThing	gallate 1-beta-glucosyltransferase activity	Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP.	got7fsn_ti	UDPglucose-vanillate 1-glucosyltransferase activity|gallate 1-b-glucosyltransferase activity|UDP-glucose-vanillate 1-glucosyltransferase activity|UDP-glucose:gallate beta-D-glucosyltransferase activity|UDPglucose:gallate glucosyltransferase activity|UDPglucose:vanillate 1-O-glucosyltransferase activity|UDPglucose:gallate beta-D-glucosyltransferase activity											KEGG_REACTION:R03297|EC:2.4.1.136|MetaCyc:GALLATE-1-BETA-GLUCOSYLTRANSFERASE-RXN|RHEA:15249		molecular_function											owl:Class	
GO:0009314	biolink:NamedThing	response to radiation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.	got7fsn_ti	response to radiation stimulus|response to electromagnetic radiation stimulus				Note that 'radiation' refers to electromagnetic radiation of any wavelength.									biological_process											owl:Class	
GO:0060974	biolink:NamedThing	cell migration involved in heart formation	The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.	got7fsn_ti							dph	2009-10-06T10:56:33Z						biological_process											owl:Class	
GO:0015934	biolink:NamedThing	large ribosomal subunit	The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).	got7fsn_ti	ribosomal large subunit													cellular_component											owl:Class	
GO:0016624	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.	got7fsn_ti	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor											EC:1.2.4.-		molecular_function											owl:Class	
GO:0030033	biolink:NamedThing	microvillus assembly	Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.	got7fsn_ti	microvillus biogenesis													biological_process											owl:Class	
GO:0032528	biolink:NamedThing	microvillus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.	got7fsn_ti	microvillus organisation|microvillus organization and biogenesis													biological_process											owl:Class	
GO:0044188	biolink:NamedThing	host cell lysosomal membrane	The lipid bilayer surrounding the host cell lysosome and separating its contents from the host cell cytoplasm.	got7fsn_ti							jl	2009-10-15T03:27:54Z						cellular_component											owl:Class	
GO:0051866	biolink:NamedThing	general adaptation syndrome	General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses.	got7fsn_ti	physiological response during general adaptation syndrome|physiological process during general adaptation syndrome|general adaptation syndrome, physiological process|general adaptation syndrome, physiological response										GO:0051868			biological_process											owl:Class	
GO:0033555	biolink:NamedThing	multicellular organismal response to stress	Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti														biological_process											owl:Class	
GO:0050076	biolink:NamedThing	maleate isomerase activity	Catalysis of the reaction: maleate = fumarate.	got7fsn_ti	maleate cis-trans-isomerase activity											MetaCyc:MALEATE-ISOMERASE-RXN|KEGG_REACTION:R01087|EC:5.2.1.1|RHEA:13169		molecular_function											owl:Class	
GO:0072030	biolink:NamedThing	short nephron development	The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.	got7fsn_ti							mah	2010-01-25T02:49:32Z						biological_process											owl:Class	
GO:0033941	biolink:NamedThing	mannan exo-1,2-1,6-alpha-mannosidase activity	Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose.	got7fsn_ti	exo-1,2-1,6-alpha-mannosidase activity|1,2-1,6-alpha-D-mannan D-mannohydrolase activity											EC:3.2.1.137|MetaCyc:3.2.1.137-RXN		molecular_function											owl:Class	
GO:0009721	biolink:NamedThing	detection of auxin stimulus	The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of auxin stimulus													biological_process											owl:Class	
GO:0019256	biolink:NamedThing	acrylonitrile catabolic process	The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.	got7fsn_ti	acrylonitrile breakdown|acrylonitrile degradation|acrylonitrile catabolism											MetaCyc:P344-PWY		biological_process											owl:Class	
GO:0046413	biolink:NamedThing	organomercury catabolic process	The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom.	got7fsn_ti	organomercury degradation|organomercury catabolism|organomercury breakdown													biological_process											owl:Class	
GO:0036279	biolink:NamedThing	positive regulation of protein export from nucleus in response to glucose starvation	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose.	got7fsn_ti							bf	2012-07-11T11:05:20Z						biological_process											owl:Class	
GO:0099506	biolink:NamedThing	synaptic vesicle transport along actin filament	The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors.	got7fsn_ti														biological_process											owl:Class	
GO:0045246	biolink:NamedThing	cytosolic tricarboxylic acid cycle enzyme complex	Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle.	got7fsn_ti	tricarboxylic acid cycle enzyme complex|TCA cycle enzyme complex													cellular_component											owl:Class	
GO:0098032	biolink:NamedThing	icosahedral viral capsid, collar fiber	A fiber attached to the collar structure of some icosahedral viral capsids.	got7fsn_ti							bm	2012-07-19T15:05:16Z						cellular_component											owl:Class	
GO:0012506	biolink:NamedThing	vesicle membrane	The lipid bilayer surrounding any membrane-bounded vesicle in the cell.	got7fsn_ti												NIF_Subcellular:sao1153182838		cellular_component											owl:Class	
GO:0003177	biolink:NamedThing	pulmonary valve development	The progression of the pulmonary valve over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-08T11:19:44Z						biological_process											owl:Class	
GO:0048321	biolink:NamedThing	axial mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell.	got7fsn_ti	axial mesoderm cell differentiation													biological_process											owl:Class	
GO:0097700	biolink:NamedThing	vascular endothelial cell response to laminar fluid shear stress	Any response to laminar fluid shear stress in a vascular endothelial cell.	got7fsn_ti	blood vessel endothelial cell response to laminar fluid shear stress						pr	2016-01-27T12:42:01Z						biological_process											owl:Class	
GO:0018891	biolink:NamedThing	cyclohexanol metabolic process	The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent.	got7fsn_ti	cyclohexanol metabolism											UM-BBD_pathwayID:chx		biological_process											owl:Class	
GO:0060208	biolink:NamedThing	proestrus	The estrous cycle phase in which there is heightened follicular activity.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:1903871	biolink:NamedThing	DNA recombinase mediator complex assembly	The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex.	got7fsn_ti	DNA recombinase mediator complex formation						rb	2015-02-05T23:05:10Z						biological_process											owl:Class	
GO:0052165	biolink:NamedThing	symbiont defense to host-produced phytoalexin	Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of phytoalexin production in other organism involved in symbiotic interaction|evasion or tolerance of phytoalexins produced by host in response to organism|response to host phytoalexin production|phytoalexin detoxification|evasion or tolerance by symbiont of host-produced phytoalexins|evasion or tolerance of phytoalexins|modulation by symbiont of host phytoalexin production|response to phytoalexin production by other organism involved in symbiotic interaction|host phytoalexin detoxification	https://github.com/geneontology/go-ontology/issues/18798									GO:0052061|GO:0052304|GO:0052378|GO:0052549|GO:0052566			biological_process											owl:Class	
GO:0016640	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule.	got7fsn_ti												EC:1.4.2.-		molecular_function											owl:Class	
GO:0046965	biolink:NamedThing	retinoid X receptor binding	Binding to a retinoid X receptor.	got7fsn_ti	RXR binding													molecular_function											owl:Class	
GO:0042974	biolink:NamedThing	retinoic acid receptor binding	Binding to a retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily.	got7fsn_ti	RAR binding													molecular_function											owl:Class	
GO:0005136	biolink:NamedThing	interleukin-4 receptor binding	Binding to an interleukin-4 receptor.	got7fsn_ti	IL-4|interleukin-4 receptor ligand													molecular_function											owl:Class	
GO:0033097	biolink:NamedThing	amyloplast membrane	Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0034233	biolink:NamedThing	regulation of cell wall chitin catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin.	got7fsn_ti	regulation of cell wall chitin catabolism|regulation of cell wall chitin degradation|regulation of cell wall chitin breakdown													biological_process											owl:Class	
GO:0034581	biolink:NamedThing	4-methyloct-2-enoyl-CoA hydratase activity	Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0925		molecular_function											owl:Class	
GO:0045543	biolink:NamedThing	gibberellin 2-beta-dioxygenase activity	Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2.	got7fsn_ti	gibberellin 2-oxidase activity|gibberellin 2-beta-hydroxylase activity|(gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|gibberellin 2beta-dioxygenase activity|gibberellin 2beta-hydroxylase activity											EC:1.14.11.13|MetaCyc:PWY-102|RHEA:15005		molecular_function											owl:Class	
GO:0071199	biolink:NamedThing	Kv4.1-DPP10 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.	got7fsn_ti	Kv4.1-DPPY channel complex						mah	2009-11-23T05:17:50Z				CORUM:601		cellular_component											owl:Class	
GO:0048687	biolink:NamedThing	positive regulation of sprouting of injured axon	Any process that activates, maintains or increases the rate of sprouting of an injured axon.	got7fsn_ti	up regulation of sprouting of injured axon|upregulation of sprouting of injured axon|up-regulation of sprouting of injured axon|stimulation of sprouting of injured axon|activation of sprouting of injured axon													biological_process											owl:Class	
GO:0048680	biolink:NamedThing	positive regulation of axon regeneration	Any process that activates, maintains or increases the rate of axon regeneration.	got7fsn_ti	up-regulation of axon regeneration|stimulation of axon regeneration|activation of axon regeneration|upregulation of axon regeneration|up regulation of axon regeneration													biological_process											owl:Class	
GO:0050120	biolink:NamedThing	N-acetylhexosamine 1-dehydrogenase activity	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate + 2 H(+) + NADH.	got7fsn_ti	N-acetyl-D-hexosamine dehydrogenase activity|N-acetylhexosamine dehydrogenase activity|N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase activity											EC:1.1.1.240|RHEA:23144|KEGG_REACTION:R01202|MetaCyc:N-ACETYLHEXOSAMINE-1-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0004320	biolink:NamedThing	oleoyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate.	got7fsn_ti	oleoyl-acyl carrier protein thioesterase activity|oleoyl-ACP hydrolase activity|oleoyl-acyl-carrier-protein hydrolase|oleoyl-[acyl-carrier protein] hydrolase activity|oleoyl-ACP thioesterase activity											RHEA:15057|EC:3.1.2.14|MetaCyc:3.1.2.14-RXN|MetaCyc:PWY-5142		molecular_function											owl:Class	
GO:0072546	biolink:NamedThing	EMC complex	A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6.	got7fsn_ti	ER membrane protein complex|endoplasmic reticulum membrane protein complex	https://github.com/geneontology/go-ontology/issues/20234			Note that this complex used to be thought to be involved in ER-mitochondrial membrane tethering, which is required to facilitate lipid transfer from the ER to the mitochondrial membrane, but newer findings show that this was incorrect.		mah	2011-01-19T06:16:53Z						cellular_component											owl:Class	
GO:0140534	biolink:NamedThing	endoplasmic reticulum protein-containing complex	A protein complex that is part of an endoplasmic reticulum.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19952					pg	2020-10-28T12:14:12Z						cellular_component											owl:Class	
GO:0047491	biolink:NamedThing	poly(alpha-L-guluronate) lyase activity	Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends.	got7fsn_ti	poly-alpha-L-guluronate lyase activity|guluronate lyase activity|L-guluronate lyase activity|polyguluronate-specific alginate lyase activity|alginase II activity|poly(alpha-L-1,4-guluronide) exo-lyase activity|L-guluronan lyase activity											EC:4.2.2.11|MetaCyc:4.2.2.11-RXN		molecular_function											owl:Class	
GO:0140671	biolink:NamedThing	ADA complex	A chromatin remodelling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and H2B. In budding yeast shares the histone acetylation (HAT) module of ADA2-GCN5-NGG1-SGF29 with the related SAGA complex.	got7fsn_ti	ADA histone acetyltransferase complex|scADA|ADA HAT complex|Ada2/Gcn5/Ada3 transcription activator complex	https://github.com/geneontology/go-ontology/issues/21335					pg	2021-06-25T11:02:49Z						cellular_component											owl:Class	
GO:1990113	biolink:NamedThing	RNA polymerase I assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex.	got7fsn_ti	RNA Polymerase I complex assembly|DNA-directed RNA polymerase I complex assembly						rb	2013-05-31T21:44:41Z						biological_process											owl:Class	
GO:0034060	biolink:NamedThing	cyanelle stroma	The space enclosed by the double membrane of a cyanelle.	got7fsn_ti														cellular_component											owl:Class	
GO:0018294	biolink:NamedThing	protein-FAD linkage via S-(8alpha-FAD)-L-cysteine	The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine.	got7fsn_ti												RESID:AA0143		biological_process											owl:Class	
GO:0008732	biolink:NamedThing	L-allo-threonine aldolase activity	Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde.	got7fsn_ti	L-allo-threonine acetaldehyde-lyase activity|LtaA											EC:4.1.2.49|MetaCyc:LTAA-RXN|RHEA:26209		molecular_function											owl:Class	
GO:0002296	biolink:NamedThing	T-helper 1 cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.	got7fsn_ti	T-helper 1 cell fate commitment|Th1 fate commitment|Th1 cell lineage commitment													biological_process											owl:Class	
GO:0002295	biolink:NamedThing	T-helper cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.	got7fsn_ti	Thp lineage commitment|Th0 lineage commitment|T-helper cell fate commitment													biological_process											owl:Class	
GO:0002513	biolink:NamedThing	tolerance induction to self antigen	Tolerance induction directed at self antigens.	got7fsn_ti														biological_process											owl:Class	
GO:0008228	biolink:NamedThing	opsonization	The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.	got7fsn_ti												Wikipedia:Opsonin		biological_process											owl:Class	
GO:0001838	biolink:NamedThing	embryonic epithelial tube formation	The morphogenesis of an embryonic epithelium into a tube-shaped structure.	got7fsn_ti														biological_process											owl:Class	
GO:1990239	biolink:NamedThing	steroid hormone binding	Binding to a steroid hormone.	got7fsn_ti							pr	2013-11-15T09:26:18Z						molecular_function											owl:Class	
GO:0005496	biolink:NamedThing	steroid binding	Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.	got7fsn_ti														molecular_function											owl:Class	
GO:0010882	biolink:NamedThing	regulation of cardiac muscle contraction by calcium ion signaling	Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.	got7fsn_ti	regulation of cardiac muscle contraction by calcium ion signalling													biological_process											owl:Class	
GO:0072742	biolink:NamedThing	SAGA complex localization to transcription regulatory region	Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene.	got7fsn_ti	SAGA complex localization to promoter|SAGA complex recruitment						mah	2012-08-24T10:36:03Z						biological_process											owl:Class	
GO:0072386	biolink:NamedThing	plus-end-directed organelle transport along microtubule	The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.	got7fsn_ti	microtubule plus-end-directed organelle distribution|microtubule plus-end-directed organelle localization						mah	2010-12-01T05:02:09Z						biological_process											owl:Class	
GO:0072384	biolink:NamedThing	organelle transport along microtubule	The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.	got7fsn_ti	microtubule-based organelle localization						mah	2010-12-01T04:59:11Z						biological_process											owl:Class	
GO:0010960	biolink:NamedThing	magnesium ion homeostasis	Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.	got7fsn_ti							tb	2009-05-06T11:47:17Z						biological_process											owl:Class	
GO:0002268	biolink:NamedThing	follicular dendritic cell differentiation	The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.	got7fsn_ti														biological_process											owl:Class	
GO:0006311	biolink:NamedThing	meiotic gene conversion	The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele.	got7fsn_ti	gene conversion without reciprocal crossover													biological_process											owl:Class	
GO:0004558	biolink:NamedThing	alpha-1,4-glucosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.	got7fsn_ti	glucoinvertase activity|alpha-glucosidase II|acid maltase activity|alpha-glucoside hydrolase activity|maltase-glucoamylase activity|alpha-glucopyranosidase activity|alpha-D-glucosidase activity|alpha-1,4-glucosidase activity|alpha-D-glucoside glucohydrolase activity|lysosomal alpha-glucosidase activity|glucosidoinvertase activity|glucosidosucrase activity										GO:0004562|GO:0016982	Reactome:R-HSA-189102|Reactome:R-HSA-5659861|Reactome:R-HSA-189053|MetaCyc:MALTODEXGLUCOSID-RXN|Reactome:R-HSA-191108|Reactome:R-HSA-191116|EC:3.2.1.20|Reactome:R-HSA-5659899|Reactome:R-HSA-5659879|Reactome:R-HSA-191101|Reactome:R-HSA-5659922		molecular_function											owl:Class	
GO:0097112	biolink:NamedThing	gamma-aminobutyric acid receptor clustering	The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane.	got7fsn_ti	GABA receptor clustering						pr	2011-07-31T05:21:08Z						biological_process											owl:Class	
GO:0052860	biolink:NamedThing	2'-deoxymugineic-acid 3-dioxygenase activity	Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2.	got7fsn_ti	2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity						ai	2011-12-05T06:00:58Z				EC:1.14.11.25|MetaCyc:RXN-7983|KEGG_REACTION:R07187|RHEA:20065		molecular_function											owl:Class	
GO:1990854	biolink:NamedThing	vacuole-ER tethering	The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles.	got7fsn_ti	vacuole-ER attachment|vacuole-endoplasmic reticulum attachment|vacuole-endoplasmic reticulum tethering						mcc	2015-09-15T18:50:04Z						biological_process											owl:Class	
GO:0051685	biolink:NamedThing	maintenance of ER location	Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of endoplasmic reticulum localization|maintenance of ER localization													biological_process											owl:Class	
GO:0034050	biolink:NamedThing	programmed cell death induced by symbiont	Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules.	got7fsn_ti	'host programmed cell death induced by symbiont'	https://github.com/geneontology/go-ontology/issues/20255			Note that this term is to be used to annotate gene products in the host, not the symbiont. To annotate gene products in the symbiont that induce programmed cell death in the host, consider the biological process term 'positive regulation by symbiont of host programmed cell death ; GO:0052042'.									biological_process											owl:Class	
GO:0004305	biolink:NamedThing	ethanolamine kinase activity	Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine.	got7fsn_ti	ethanolamine kinase (phosphorylating)|ethanolamine phosphokinase activity|ATP:ethanolamine O-phosphotransferase activity											KEGG_REACTION:R01468|MetaCyc:ETHANOLAMINE-KINASE-RXN|EC:2.7.1.82|Reactome:R-HSA-1483222|RHEA:13069		molecular_function											owl:Class	
GO:0005619	biolink:NamedThing	ascospore wall	The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.	got7fsn_ti	fungal-type spore wall													cellular_component											owl:Class	
GO:0085001	biolink:NamedThing	formation of stylet for nutrient acquisition	The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	formation by symbiont of stylet for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305					jl	2010-02-24T01:49:06Z						biological_process											owl:Class	
GO:0018295	biolink:NamedThing	protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine	The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine.	got7fsn_ti												RESID:AA0144		biological_process											owl:Class	
GO:0000432	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by glucose	Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.	got7fsn_ti	stimulation of transcription from RNA polymerase II promoter by glucose|activation of transcription from RNA polymerase II promoter by glucose|upregulation of transcription from RNA polymerase II promoter by glucose|up-regulation of transcription from RNA polymerase II promoter by glucose|up regulation of transcription from RNA polymerase II promoter by glucose													biological_process											owl:Class	
GO:0030793	biolink:NamedThing	3'-demethylstaurosporine O-methyltransferase activity	Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H(+) + staurosporine.	got7fsn_ti	staurosporine synthase activity|3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase activity|S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase activity											EC:2.1.1.139|RHEA:11696|KEGG_REACTION:R05757|MetaCyc:2.1.1.139-RXN		molecular_function											owl:Class	
GO:0000429	biolink:NamedThing	carbon catabolite regulation of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter by carbon catabolites													biological_process											owl:Class	
GO:0071757	biolink:NamedThing	hexameric IgM immunoglobulin complex	A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide.	got7fsn_ti	hexameric IgM antibody				Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0071754	biolink:NamedThing	IgM immunoglobulin complex, circulating	A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph.	got7fsn_ti	IgM antibody				Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0016664	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	got7fsn_ti	oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulphur protein as acceptor											EC:1.7.7.-		molecular_function											owl:Class	
GO:0050178	biolink:NamedThing	phenylpyruvate tautomerase activity	Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate.	got7fsn_ti	phenylpyruvate keto-enol-isomerase activity|phenylpyruvate keto--enol tautomerase activity|phenylpyruvic keto--enol isomerase activity											RHEA:17097|MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN|EC:5.3.2.1		molecular_function											owl:Class	
GO:0051945	biolink:NamedThing	negative regulation of catecholamine uptake involved in synaptic transmission	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.	got7fsn_ti	down regulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine neurotransmitter uptake|negative regulation of catecholamine neurotransmitter reuptake|negative regulation of catecholamine uptake during transmission of nerve impulse|down-regulation of catecholamine uptake during transmission of nerve impulse|downregulation of catecholamine uptake during transmission of nerve impulse|inhibition of catecholamine uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0052739	biolink:NamedThing	phosphatidylserine 1-acylhydrolase activity	Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid.	got7fsn_ti	phosphatidylserine-specific phospholipase A1 activity											EC:3.1.1.32|KEGG_REACTION:R04034|Reactome:R-HSA-8869425		molecular_function											owl:Class	
GO:0120243	biolink:NamedThing	2-iminopropanoate deaminase activity	Catalysis of the reaction: 2-iminopropanoate + H2O = NH4(+) + pyruvate.	got7fsn_ti	2-iminobutanoate/2-iminopropanoate deaminase	https://github.com/geneontology/go-ontology/issues/19832					krc	2020-07-29T19:41:18Z				KEGG_REACTION:R11099|MetaCyc:RXN-15127|RHEA:40671		molecular_function											owl:Class	
GO:0072231	biolink:NamedThing	metanephric proximal convoluted tubule segment 1 development	The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.	got7fsn_ti	metanephric S1 development						mah	2010-03-18T03:39:10Z						biological_process											owl:Class	
GO:0035079	biolink:NamedThing	polytene chromosome puffing	The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.	got7fsn_ti														biological_process											owl:Class	
GO:0047973	biolink:NamedThing	guanidinoacetate kinase activity	Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H(+) + phosphoguanidinoacetate.	got7fsn_ti	glycocyamine kinase activity|ATP:guanidinoacetate N-phosphotransferase activity|guanidoacetate kinase activity											MetaCyc:GUANIDOACETATE-KINASE-RXN|KEGG_REACTION:R02575|EC:2.7.3.1|RHEA:14145		molecular_function											owl:Class	
GO:0060425	biolink:NamedThing	lung morphogenesis	The process in which the anatomical structures of the lung are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0044418	biolink:NamedThing	translocation of DNA into host	The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	transport of DNA into other organism during symbiotic interaction|transport of DNA into host|translocation of DNA into other organism during symbiotic interaction|translocation of DNA into other organism involved in symbiotic interaction										GO:0051837			biological_process											owl:Class	
GO:0043823	biolink:NamedThing	spheroidene monooxygenase activity	Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O.	got7fsn_ti												RHEA:33027|EC:1.14.15.9|MetaCyc:RXN-10670		molecular_function											owl:Class	
GO:0019310	biolink:NamedThing	inositol catabolic process	The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.	got7fsn_ti	myo-inositol catabolic process|inositol degradation|inositol catabolism|inositol breakdown|vitamin Bh catabolic process|vitamin Bh catabolism|myo-inositol catabolism											MetaCyc:P562-PWY		biological_process											owl:Class	
GO:0036524	biolink:NamedThing	protein deglycase activity	Catalysis of the removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.	got7fsn_ti	protein deglycating enzyme						bf	2016-08-04T10:23:33Z				MetaCyc:RXN-17634|MetaCyc:RXN-17630|MetaCyc:RXN-17632		molecular_function											owl:Class	
GO:0060219	biolink:NamedThing	camera-type eye photoreceptor cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.	got7fsn_ti														biological_process											owl:Class	
GO:0022037	biolink:NamedThing	metencephalon development	The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0052917	biolink:NamedThing	dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase	Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol.	got7fsn_ti	dolichyl-P-mannose:Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity	https://github.com/geneontology/go-ontology/issues/19075									GO:0052824	EC:2.4.1.260|RHEA:29535|MetaCyc:RXN-5468|KEGG_REACTION:R06260		molecular_function											owl:Class	
GO:0140624	biolink:NamedThing	EGAD pathway	The protein catabolic pathway which selectively extracts ER-resident membrane proteins exported to the Golgi and endosomes for degradation by cytosolic proteasomes. It begins with phosphorylation of the ER-resident membrane protein, which triggers export of the protein from the ER to the Golgi and endosomes, followed by polyubiquitination by the Dsc E3 ubiquitin ligase complex and extraction of the ubiquitinated target, and ends with proteasomal degradation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21085					pg	2021-03-12T10:41:58Z						biological_process											owl:Class	
GO:0034477	biolink:NamedThing	U6 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U6 snRNA molecule.	got7fsn_ti	U6 snRNA 3' end processing													biological_process											owl:Class	
GO:0003980	biolink:NamedThing	UDP-glucose:glycoprotein glucosyltransferase activity	Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.	got7fsn_ti	UGGT activity											Reactome:R-HSA-548884		molecular_function											owl:Class	
GO:0090333	biolink:NamedThing	regulation of stomatal closure	Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.	got7fsn_ti							tb	2010-05-26T02:14:49Z						biological_process											owl:Class	
GO:0010119	biolink:NamedThing	regulation of stomatal movement	Any process that modulates the frequency, rate or extent of stomatal movement.	got7fsn_ti														biological_process											owl:Class	
GO:0051472	biolink:NamedThing	glucosylglycerol metabolic process	The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.	got7fsn_ti	glucosylglycerol metabolism													biological_process											owl:Class	
GO:0034260	biolink:NamedThing	negative regulation of GTPase activity	Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.	got7fsn_ti	downregulation of Rab GTPase activity|down regulation of Rab GTPase activity|downregulation of GTPase activity|down regulation of Ras GTPase activity|down-regulation of Rab GTPase activity|down-regulation of Ras GTPase activity|inhibition of Rab GTPase activity|inhibition of regulation of Ran GTPase activity|inhibition of GTPase activity|inhibition of Rho GTPase activity|inhibition of Ras GTPase activity|downregulation of regulation of Ran GTPase activity|down regulation of GTPase activity|down regulation of regulation of Ran GTPase activity|downregulation of Ras GTPase activity|down-regulation of Rho GTPase activity|downregulation of Rho GTPase activity|negative regulation of Ras GTPase activity|negative regulation of guanosinetriphosphatase activity|negative regulation of Ran GTPase activity|down regulation of Rho GTPase activity|negative regulation of Rho GTPase activity|negative regulation of Rab GTPase activity|down-regulation of GTPase activity|down-regulation of regulation of Ran GTPase activity				An example of this is P2xA in Dictyostelium (UniProt symbol Q86JM7) in PMID:24335649.						GO:0034259|GO:0034261|GO:1902264|GO:1902881			biological_process											owl:Class	
GO:0034446	biolink:NamedThing	substrate adhesion-dependent cell spreading	The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.	got7fsn_ti	cell spreading during cell substrate adhesion|substrate adhesion dependent cell spreading													biological_process											owl:Class	
GO:0060988	biolink:NamedThing	lipid tube assembly	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission.	got7fsn_ti	lipid tubulation						dph	2010-01-11T01:56:59Z						biological_process											owl:Class	
GO:0032944	biolink:NamedThing	regulation of mononuclear cell proliferation	Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.	got7fsn_ti	regulation of peripheral blood mononuclear cell proliferation|regulation of PBMC proliferation													biological_process											owl:Class	
GO:0102134	biolink:NamedThing	(22S)-22-hydroxy-campesterol C-23 hydroxylase activity	Catalysis of the reaction: H+ + (22S)-22-hydroxycampesterol + NADPH + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-11529		molecular_function											owl:Class	
GO:0003747	biolink:NamedThing	translation release factor activity	Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.	got7fsn_ti											GO:0003749|GO:0003748			molecular_function											owl:Class	
GO:0045498	biolink:NamedThing	sex comb development	The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.	got7fsn_ti														biological_process											owl:Class	
GO:0071349	biolink:NamedThing	cellular response to interleukin-12	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.	got7fsn_ti	cellular response to IL-12						mah	2009-12-11T02:49:40Z						biological_process											owl:Class	
GO:0034809	biolink:NamedThing	benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity	Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2.	got7fsn_ti												UM-BBD_reactionID:r1127		molecular_function											owl:Class	
GO:0043911	biolink:NamedThing	D-lysine transaminase activity	Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate.	got7fsn_ti	D-lysine aminotransferase activity													molecular_function											owl:Class	
GO:0050882	biolink:NamedThing	voluntary musculoskeletal movement	The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will.	got7fsn_ti														biological_process											owl:Class	
GO:0035974	biolink:NamedThing	meiotic spindle pole body	The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome.	got7fsn_ti							bf	2011-08-16T11:37:59Z						cellular_component											owl:Class	
GO:0010408	biolink:NamedThing	fasciclin-like arabinogalactan protein metabolic process	The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain.	got7fsn_ti	fasciclin-like arabinogalactan protein metabolism													biological_process											owl:Class	
GO:0035696	biolink:NamedThing	monocyte extravasation	The migration of a monocyte from the blood vessels into the surrounding tissue.	got7fsn_ti							bf	2011-02-28T03:05:52Z						biological_process											owl:Class	
GO:0048824	biolink:NamedThing	pigment cell precursor differentiation	The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor.	got7fsn_ti	chromatophore precursor differentiation													biological_process											owl:Class	
GO:0000430	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter by glucose	Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti														biological_process											owl:Class	
GO:0090304	biolink:NamedThing	nucleic acid metabolic process	Any cellular metabolic process involving nucleic acids.	got7fsn_ti							tb	2010-04-07T10:18:47Z						biological_process											owl:Class	
GO:0033515	biolink:NamedThing	L-lysine catabolic process using lysine 6-aminotransferase	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase.	got7fsn_ti	L-lysine breakdown using lysine 6-aminotransferase|L-lysine degradation using lysine 6-aminotransferase											MetaCyc:PWY-5298		biological_process											owl:Class	
GO:0007124	biolink:NamedThing	pseudohyphal growth	The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli.	got7fsn_ti														biological_process											owl:Class	
GO:1990823	biolink:NamedThing	response to leukemia inhibitory factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.	got7fsn_ti	response to LIF|response to cholinergic differentiation factor|response to CDF						sl	2015-08-19T16:44:21Z						biological_process											owl:Class	
GO:0042970	biolink:NamedThing	homoserine transmembrane transporter activity	Enables the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.	got7fsn_ti	homoserine transporter activity													molecular_function											owl:Class	
GO:0019786	biolink:NamedThing	Atg8-specific protease activity	Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.	got7fsn_ti	APG8-PE hydrolase|APG8-specific protease activity													molecular_function											owl:Class	
GO:2000640	biolink:NamedThing	positive regulation of SREBP signaling pathway	Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway.	got7fsn_ti	positive regulation of SREBP-mediated signaling pathway|positive regulation of SREBP-mediated signalling pathway						vk	2011-04-20T02:46:05Z						biological_process											owl:Class	
GO:0048842	biolink:NamedThing	positive regulation of axon extension involved in axon guidance	Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance.	got7fsn_ti	up-regulation of axon extension involved in axon guidance|stimulation of axon extension involved in axon guidance|activation of axon extension involved in axon guidance|up regulation of axon extension involved in axon guidance|upregulation of axon extension involved in axon guidance													biological_process											owl:Class	
GO:0050921	biolink:NamedThing	positive regulation of chemotaxis	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.	got7fsn_ti	activation of chemotaxis|stimulation of chemotaxis|up regulation of chemotaxis|up-regulation of chemotaxis|upregulation of chemotaxis													biological_process											owl:Class	
GO:0051904	biolink:NamedThing	pigment granule transport	The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	pigment granule translocation													biological_process											owl:Class	
GO:1990110	biolink:NamedThing	callus formation	The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.	got7fsn_ti							tb	2013-05-29T22:02:52Z						biological_process											owl:Class	
GO:0099124	biolink:NamedThing	axonal dopamine secretion	The regulated release of dopamine from an axon.	got7fsn_ti	axonal DA release|axonal dopamine release													biological_process											owl:Class	
GO:0051564	biolink:NamedThing	positive regulation of smooth endoplasmic reticulum calcium ion concentration	Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum.	got7fsn_ti	smooth endoplasmic reticulum calcium ion concentration elevation|elevation of smooth endoplasmic reticulum calcium ion concentration|elevation of calcium ion concentration in smooth endoplasmic reticulum|elevation of smooth ER calcium ion concentration													biological_process											owl:Class	
GO:0016233	biolink:NamedThing	telomere capping	A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.	got7fsn_ti	telomere end protection													biological_process											owl:Class	
GO:0016603	biolink:NamedThing	glutaminyl-peptide cyclotransferase activity	Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3.	got7fsn_ti	glutaminyl cyclase activity|glutaminyl-tRNA cyclotransferase activity|glutaminyl-transfer ribonucleate cyclotransferase activity|L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing)											RHEA:23652|MetaCyc:GLUTAMINYL-PEPTIDE-CYCLOTRANSFERASE-RXN|EC:2.3.2.5		molecular_function											owl:Class	
GO:0033098	biolink:NamedThing	amyloplast inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma.	got7fsn_ti														cellular_component											owl:Class	
GO:0002682	biolink:NamedThing	regulation of immune system process	Any process that modulates the frequency, rate, or extent of an immune system process.	got7fsn_ti														biological_process											owl:Class	
GO:0032867	biolink:NamedThing	L-arabinose:NADP reductase activity	Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+.	got7fsn_ti	arabinose reductase activity|arabinose:NADP reductase activity											KEGG_REACTION:R01759|RHEA:25229|SABIO-RK:1858|MetaCyc:RXN-8772		molecular_function											owl:Class	
GO:0071933	biolink:NamedThing	Arp2/3 complex binding	Binding to an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).	got7fsn_ti							mah	2010-09-29T02:48:41Z						molecular_function											owl:Class	
GO:1990840	biolink:NamedThing	response to lectin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.	got7fsn_ti					This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity.		sl	2015-08-27T20:02:21Z						biological_process											owl:Class	
GO:0033928	biolink:NamedThing	mannan 1,4-mannobiosidase activity	Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.	got7fsn_ti	exo-1,4-beta-mannobiohydrolase activity|exo-beta-mannanase activity|mannan 1,4-beta-mannobiosidase activity|1,4-beta-D-mannan mannobiohydrolase activity											EC:3.2.1.100|MetaCyc:3.2.1.100-RXN		molecular_function											owl:Class	
GO:0039009	biolink:NamedThing	rectal diverticulum development	The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior.	got7fsn_ti	pronephric rectal diverticulum development						bf	2010-07-02T09:48:58Z						biological_process											owl:Class	
GO:0016768	biolink:NamedThing	spermine synthase activity	Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.	got7fsn_ti	spermine synthetase activity|S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity|spermidine aminopropyltransferase activity											Reactome:R-HSA-351210|EC:2.5.1.22|MetaCyc:SPERMINE-SYNTHASE-RXN|RHEA:19973		molecular_function											owl:Class	
GO:0023022	biolink:NamedThing	termination of T cell signal transduction	The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.	got7fsn_ti								2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0031172	biolink:NamedThing	ornithine N5-monooxygenase activity	Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.	got7fsn_ti	L-ornithine 5-monooxygenase activity											RHEA:41508|MetaCyc:RXN-11128		molecular_function											owl:Class	
GO:0048317	biolink:NamedThing	seed morphogenesis	The process in which the anatomical structures of the seed are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0102218	biolink:NamedThing	starch, H2O dikinase activity	Catalysis of the reaction: n ATP + n H2O + starch = n AMP + n hydrogenphosphate + a 6-phosphogluco-amylopectin.	got7fsn_ti												EC:2.7.9.4|MetaCyc:RXN-12203		molecular_function											owl:Class	
GO:0050521	biolink:NamedThing	alpha-glucan, water dikinase activity	Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate.	got7fsn_ti	starch-related R1 protein activity|alpha-glucan,water dikinase activity|GWD|a-glucan, water dikinase activity|ATP:alpha-glucan, water phosphotransferase activity											MetaCyc:2.7.9.4-RXN|EC:2.7.9.4|RHEA:11668		molecular_function											owl:Class	
GO:0018624	biolink:NamedThing	toluene dioxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+).	got7fsn_ti	toluene 1,2-dioxygenase activity|toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)|toluene 2,3-dioxygenase activity											KEGG_REACTION:R03559|EC:1.14.12.11|MetaCyc:TOLUENE-DIOXYGENASE-RXN|RHEA:16737|UM-BBD_enzymeID:e0155		molecular_function											owl:Class	
GO:0080149	biolink:NamedThing	sucrose induced translational repression	Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level.	got7fsn_ti	negative regulation of translation in response to sucrose						dhl	2010-03-26T04:13:15Z						biological_process											owl:Class	
GO:0032055	biolink:NamedThing	negative regulation of translation in response to stress	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.	got7fsn_ti	down-regulation of translation in response to stress|inhibition of translation in response to stress|downregulation of translation in response to stress|down regulation of translation in response to stress													biological_process											owl:Class	
GO:0038088	biolink:NamedThing	VEGF-activated platelet-derived growth factor receptor-beta signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	VEGF-A/PDGFRbeta signaling|VEGF-activated PDGFRbeta signalling pathway|VEGF/PDGFRbeta signaling pathway|VEGF-activated platelet-derived growth factor receptor-beta signalling pathway|vascular endothelial growth factor-activated platelet-derived growth factor receptor-beta signaling pathway						bf	2012-02-01T03:10:16Z						biological_process											owl:Class	
GO:0035791	biolink:NamedThing	platelet-derived growth factor receptor-beta signaling pathway	A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	PDGFR-beta signaling pathway|betaPDGF receptor signaling pathway|platelet-derived growth factor receptor-beta signalling pathway|PDGF receptor-beta signaling pathway						bf	2011-04-06T10:57:04Z						biological_process											owl:Class	
GO:0102787	biolink:NamedThing	caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-beta-D-caffeoylglucoside + coenzyme A.	got7fsn_ti												MetaCyc:RXN-7997		molecular_function											owl:Class	
GO:0018836	biolink:NamedThing	alkylmercury lyase activity	Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+.	got7fsn_ti	organomercurial lyase activity|alkylmercury mercuric-lyase (alkane-forming)|alkylmercury mercuric-lyase activity|organomercury lyase activity											EC:4.99.1.2|MetaCyc:ALKYLMERCURY-LYASE-RXN|UM-BBD_enzymeID:e0055|RHEA:18777		molecular_function											owl:Class	
GO:0098924	biolink:NamedThing	retrograde trans-synaptic signaling by nitric oxide	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.	got7fsn_ti														biological_process											owl:Class	
GO:0060423	biolink:NamedThing	foregut regionalization	The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.	got7fsn_ti														biological_process											owl:Class	
GO:0103041	biolink:NamedThing	thiosulfate-thioredoxin sulfurtransferase activity	Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin.	got7fsn_ti												MetaCyc:RXN0-6385		molecular_function											owl:Class	
GO:0030159	biolink:NamedThing	signaling receptor complex adaptor activity	The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex.	got7fsn_ti	receptor signaling complex scaffold protein activity|receptor signaling complex scaffold activity|receptor signalling complex adaptor activity|receptor signaling complex adaptor activity|receptor signalling complex scaffold activity													molecular_function											owl:Class	
GO:0034266	biolink:NamedThing	isopentenyl adenine catabolic process	The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.	got7fsn_ti	isopentenyl adenine breakdown|isopentenyl adenine catabolism|isopentenyl adenine degradation|isopentenyladenine catabolic process													biological_process											owl:Class	
GO:0009823	biolink:NamedThing	cytokinin catabolic process	The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators.	got7fsn_ti	cytokinin catabolism|cytokinin degradation|cytokinin breakdown													biological_process											owl:Class	
GO:0047136	biolink:NamedThing	4-(dimethylamino)phenylazoxybenzene reductase activity	Catalysis of the reaction: 4-(dimethylamino)azobenzene + H(2)O + NADP(+) = 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH.	got7fsn_ti	dimethylaminoazobenzene N-oxide reductase activity|N,N-dimethyl-p-aminoazobenzene oxide reductase activity|NADPH2:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity|NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity|4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase activity|NADPH-dependent DMAB N-oxide reductase activity											RHEA:19789|MetaCyc:1.6.6.12-RXN|EC:1.7.1.11|KEGG_REACTION:R04303		molecular_function											owl:Class	
GO:1990453	biolink:NamedThing	nucleosome disassembly/reassembly complex	A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex.	got7fsn_ti	eaf5/7/3 complex				An example of this is EAF7 in Saccharomyces cerevisiae (P53911) in PMID:24843044 (inferred from direct assay).		bhm	2014-08-08T15:18:30Z						cellular_component											owl:Class	
GO:0046016	biolink:NamedThing	positive regulation of transcription by glucose	Any process involving glucose that activates or increases the rate of transcription.	got7fsn_ti	upregulation of transcription by glucose|stimulation of transcription by glucose|activation of transcription by glucose|up-regulation of transcription by glucose|up regulation of transcription by glucose													biological_process											owl:Class	
GO:0000112	biolink:NamedThing	nucleotide-excision repair factor 3 complex	One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p).	got7fsn_ti	NEF3 complex				Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.									cellular_component											owl:Class	
GO:0097212	biolink:NamedThing	lysosomal membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.	got7fsn_ti	lysosomal membrane organisation|lysosome membrane organization						pr	2012-01-12T10:16:15Z						biological_process											owl:Class	
GO:0070213	biolink:NamedThing	protein auto-ADP-ribosylation	The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.	got7fsn_ti	protein amino acid auto-ADP-ribosylation													biological_process											owl:Class	
GO:0052771	biolink:NamedThing	coenzyme F390-G hydrolase activity	Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420.	got7fsn_ti	8-hydroxyguanylylated-coenzyme F420 hydrolase activity						ai	2011-10-03T12:00:00Z						molecular_function											owl:Class	
GO:0086069	biolink:NamedThing	bundle of His cell to Purkinje myocyte communication	The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti	atrioventricular junction myocyte to bundle branch myocyte|bundle branch myocyte to Purkinje myocyte communication|bundle of His cardiac muscle cell to Purkinje myocyte communication|ventricular conduction system cell to cell communication|bundle of His myocyte to atrioventricular junction myocyte	https://github.com/geneontology/go-ontology/issues/20731					dph	2011-11-22T09:18:49Z						biological_process											owl:Class	
GO:0007539	biolink:NamedThing	primary sex determination, soma	The transmission of information about sexual status from the initial, general, determination to signals specific to the soma.	got7fsn_ti														biological_process											owl:Class	
GO:0007538	biolink:NamedThing	primary sex determination	The sex determination process that results in the initial specification of sexual status of an individual organism.	got7fsn_ti														biological_process											owl:Class	
GO:0002542	biolink:NamedThing	Factor XII activation	Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade.	got7fsn_ti	Hageman factor activation													biological_process											owl:Class	
GO:0080024	biolink:NamedThing	indolebutyric acid metabolic process	The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants.	got7fsn_ti	IBA metabolism|indole-3-butyric acid metabolic process|IBA metabolic process													biological_process											owl:Class	
GO:0099009	biolink:NamedThing	viral genome circularization	The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities.	got7fsn_ti												VZ:3968		biological_process											owl:Class	
GO:0070097	biolink:NamedThing	delta-catenin binding	Binding to the delta subunit of the catenin complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0099071	biolink:NamedThing	dynamic microtubule bundle	A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place.	got7fsn_ti														cellular_component											owl:Class	
GO:0051912	biolink:NamedThing	CoB--CoM heterodisulfide reductase activity	Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine.	got7fsn_ti	coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|heterodisulfide reductase activity|soluble heterodisulfide reductase activity|coenzyme B:coenzyme M:methanophenazine oxidoreductase activity|CoB-CoM heterodisulfide reductase activity|coenzyme B--coenzyme M heterodisulfide reductase activity											EC:1.8.98.1|RHEA:18085|MetaCyc:1.8.98.1-RXN		molecular_function											owl:Class	
GO:0043577	biolink:NamedThing	chemotropism	The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it.	got7fsn_ti												Wikipedia:Chemotropism		biological_process											owl:Class	
GO:0016420	biolink:NamedThing	malonyltransferase activity	Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0039585	biolink:NamedThing	PKR-mediated signaling	A series of reactions in which a signal is passed on to downstream proteins within the cell via PKR (also known as EIF2AK3), an intracellular protein kinase that is activated by stress signals or upon binding to double-stranded RNA (dsRNA), followed by autophosphorylation. PKR plays a role in the antiviral response, phosphorylating proteins such as the translation initiation factor eIF2 to inhibit protein synthesis during viral infection. Begins with activation of PKR activity, and ends with regulation of a downstream cellular process, e.g. regulation of transcription or inhibition of translation.	got7fsn_ti	EIF2AK3/PERK signaling|signaling through PKR|PKR signaling pathway|EIF2AK3 signal transduction|PKR signal transduction						bf	2012-05-02T04:15:10Z						biological_process											owl:Class	
GO:0120049	biolink:NamedThing	snRNA (adenine-N6)-methylation	The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule.	got7fsn_ti							krc	2017-06-02T20:56:51Z						biological_process											owl:Class	
GO:0040031	biolink:NamedThing	snRNA modification	The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0015328	biolink:NamedThing	cystine secondary active transmembrane transporter activity	Enables the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	lysosomal cystine transporter|cystine porter activity|cystinosin													molecular_function											owl:Class	
GO:0005294	biolink:NamedThing	neutral L-amino acid secondary active transmembrane transporter activity	Enables the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	neutral L-amino acid porter activity													molecular_function											owl:Class	
GO:0048244	biolink:NamedThing	phytanoyl-CoA dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + O(2) + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO(2) + succinate.	got7fsn_ti	phytanoyl-CoA 2-hydroxylase activity|phytanoyl-CoA 2 oxoglutarate dioxygenase activity|phytanoyl-CoA alpha-hydroxylase activity|phytanoyl-CoA hydroxylase activity|phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)											MetaCyc:1.14.11.18-RXN|RHEA:16065|EC:1.14.11.18|Reactome:R-HSA-389639|KEGG_REACTION:R05722		molecular_function											owl:Class	
GO:0090597	biolink:NamedThing	nematode male tail mating organ morphogenesis	The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules.	got7fsn_ti							tb	2014-08-22T13:25:22Z						biological_process											owl:Class	
GO:0033621	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.	got7fsn_ti	mRNA degradation, meiosis-specific transcripts|mRNA catabolism, meiosis-specific transcripts|mRNA breakdown, meiosis-specific transcripts|degradation of meiosis-specific transcripts|nuclear mRNA catabolic process, meiosis-specific transcripts				Note that it is speculated that higher eukaryotic YTH-family protein may be involved in similar mechanisms to supress gene regulation during gametogenesis or general silencing.									biological_process											owl:Class	
GO:0016607	biolink:NamedThing	nuclear speck	A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.	got7fsn_ti	nuclear speckles|nuclear speckle|speckle focus|speckle domain|splicing speckle													cellular_component											owl:Class	
GO:0018237	biolink:NamedThing	urease activator activity	Increases the activity of urease by promoting the incorporation of nickel into the active site.	got7fsn_ti	urease activase activity													molecular_function											owl:Class	
GO:0071724	biolink:NamedThing	response to diacyl bacterial lipopeptide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.	got7fsn_ti	response to diacylated bacterial lipoprotein				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:14:41Z						biological_process											owl:Class	
GO:0048314	biolink:NamedThing	embryo sac morphogenesis	The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.	got7fsn_ti	female gametophyte morphogenesis													biological_process											owl:Class	
GO:0097073	biolink:NamedThing	interferon regulatory factor 5 complex	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 5.	got7fsn_ti	IRF5:IRF5 complex						pr	2011-06-15T04:28:57Z						cellular_component											owl:Class	
GO:0052861	biolink:NamedThing	glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group	Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.	got7fsn_ti	laminarinase activity|laminaranase activity|1,3-(1,3)-beta-D-glucan 3-glucanohydrolase activity						ai	2011-12-06T04:49:36Z				EC:3.2.1.6|MetaCyc:3.2.1.6-RXN		molecular_function											owl:Class	
GO:0052736	biolink:NamedThing	beta-glucanase activity	Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds.	got7fsn_ti	beta-D-glucanase activity							2011-08-19T03:40:56Z						molecular_function											owl:Class	
GO:0034396	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to iron	Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.	got7fsn_ti	down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of transcription from Pol II promoter in response to iron													biological_process											owl:Class	
GO:0031567	biolink:NamedThing	mitotic cell size control checkpoint signaling	A signal transduction process that contributes to a cell size control checkpoint during mitosis.	got7fsn_ti	mitotic cell size control checkpoint|mitotic cell cycle cell size control checkpoint|signal transduction involved in cell size control checkpoint										GO:0072471			biological_process											owl:Class	
GO:0047099	biolink:NamedThing	CDP-4-dehydro-6-deoxyglucose reductase activity	Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose.	got7fsn_ti	NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase activity|cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase activity|CDP-4-keto-deoxy-glucose reductase activity|CDP-4-keto-6-deoxyglucose reductase activity|CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system activity|cytidine diphospho-4-keto-6-deoxy-D-glucose reductase activity|CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase activity											EC:1.17.1.1|MetaCyc:1.17.1.1-RXN		molecular_function											owl:Class	
GO:0010079	biolink:NamedThing	maintenance of vegetative meristem identity	The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0106030	biolink:NamedThing	neuron projection fasciculation	The collection of neuronal projections into a bundle of rods, known as a fascicle.	got7fsn_ti							hjd	2017-06-26T19:43:23Z						biological_process											owl:Class	
GO:0050747	biolink:NamedThing	positive regulation of lipoprotein metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	got7fsn_ti	stimulation of lipoprotein metabolic process|up-regulation of lipoprotein metabolic process|activation of lipoprotein metabolic process|upregulation of lipoprotein metabolic process|positive regulation of lipoprotein metabolism|up regulation of lipoprotein metabolic process													biological_process											owl:Class	
GO:0043717	biolink:NamedThing	2-hydroxyglutaryl-CoA dehydratase activity	Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA.	got7fsn_ti	(R)-2-hydroxyglutaryl-CoA dehydratase activity											MetaCyc:RXN-1083|RHEA:42448		molecular_function											owl:Class	
GO:0031849	biolink:NamedThing	olfactory receptor binding	Binding to an olfactory receptor.	got7fsn_ti	olfactory receptor ligand													molecular_function											owl:Class	
GO:0010365	biolink:NamedThing	positive regulation of ethylene biosynthetic process	Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process.	got7fsn_ti														biological_process											owl:Class	
GO:0031337	biolink:NamedThing	positive regulation of sulfur amino acid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.	got7fsn_ti	upregulation of sulfur amino acid metabolic process|up regulation of sulfur amino acid metabolic process|up-regulation of sulfur amino acid metabolic process|positive regulation of sulfur amino acid metabolism|stimulation of sulfur amino acid metabolic process|activation of sulfur amino acid metabolic process													biological_process											owl:Class	
GO:0070722	biolink:NamedThing	Tle3-Aes complex	A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product.	got7fsn_ti	Grg3b-Grg5 complex						mah	2009-06-10T05:45:28Z						cellular_component											owl:Class	
GO:0042105	biolink:NamedThing	alpha-beta T cell receptor complex	A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein.	got7fsn_ti	alpha-beta T lymphocyte receptor complex|alpha-beta TCR complex|alpha-beta T-lymphocyte receptor complex|alpha-beta T-cell receptor complex													cellular_component											owl:Class	
GO:0072441	biolink:NamedThing	response to meiotic DNA replication checkpoint signaling	A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling.	got7fsn_ti	response to signal involved in meiotic DNA replication checkpoint|meiotic DNA replication checkpoint effector process						mah	2010-12-08T04:59:26Z						biological_process											owl:Class	
GO:0018807	biolink:NamedThing	6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity	Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA.	got7fsn_ti												EC:3.7.1.21|UM-BBD_reactionID:r0204|RHEA:39651		molecular_function											owl:Class	
GO:0021757	biolink:NamedThing	caudate nucleus development	The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.	got7fsn_ti														biological_process											owl:Class	
GO:0034457	biolink:NamedThing	Mpp10 complex	A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p.	got7fsn_ti					Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.									cellular_component											owl:Class	
GO:0007042	biolink:NamedThing	lysosomal lumen acidification	Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.	got7fsn_ti	lysosome pH reduction													biological_process											owl:Class	
GO:0070866	biolink:NamedThing	sterol-dependent protein binding	Binding to a protein or protein complex in the presence of sterols.	got7fsn_ti							mah	2009-08-19T01:43:35Z						molecular_function											owl:Class	
GO:0140608	biolink:NamedThing	cysteine-type endopeptidase activator activity	Binds to and increases the activity of a cysteine-type endopeptidase.	got7fsn_ti	caspase activator activator activity	https://github.com/geneontology/go-ontology/issues/20916					pg	2021-02-18T08:58:58Z						molecular_function											owl:Class	
GO:0061133	biolink:NamedThing	endopeptidase activator activity	Binds to and increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.	got7fsn_ti							dph	2010-05-17T01:08:29Z						molecular_function											owl:Class	
GO:0071815	biolink:NamedThing	intermediate-density lipoprotein particle binding	Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.	got7fsn_ti	IDL binding|intermediate-density lipoprotein binding						mah	2010-09-06T04:28:35Z						molecular_function											owl:Class	
GO:0080026	biolink:NamedThing	response to indolebutyric acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.	got7fsn_ti	response to indolebutyric acid stimulus|response to indole-3-butyric acid stimulus|response to IBA stimulus													biological_process											owl:Class	
GO:1990959	biolink:NamedThing	eosinophil homeostasis	The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti	eosinophilic granulocyte homeostasis|eosinophilic leucocyte homeostasis|eosinophilic leukocyte homeostasis|eosinocyte homeostasis						sl	2016-06-06T22:34:31Z						biological_process											owl:Class	
GO:0000010	biolink:NamedThing	trans-hexaprenyltranstransferase activity	Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate.	got7fsn_ti												RHEA:20836		molecular_function											owl:Class	
GO:0030253	biolink:NamedThing	protein secretion by the type I secretion system	The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.	got7fsn_ti	type I protein secretion system|protein secretion by the TOSS|protein secretion by the type I protein secretion system				Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type I protein secretion system complex ; GO:0030256'.									biological_process											owl:Class	
GO:0018014	biolink:NamedThing	N-terminal peptidyl-methionine methylation	The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine.	got7fsn_ti												RESID:AA0064		biological_process											owl:Class	
GO:0031215	biolink:NamedThing	shell calcification	The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell.	got7fsn_ti														biological_process											owl:Class	
GO:0047181	biolink:NamedThing	tetrahydroxybenzophenone synthase activity	Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A.	got7fsn_ti	malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase activity											EC:2.3.1.151|MetaCyc:2.3.1.151-RXN|RHEA:19305		molecular_function											owl:Class	
GO:0000949	biolink:NamedThing	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.	got7fsn_ti														biological_process											owl:Class	
GO:0140359	biolink:NamedThing	ABC-type transporter activity	Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.	got7fsn_ti	ATP-binding cassette transporter|ABC-type efflux porter activity|ABC-type efflux permease activity|ATP binding cassette transporter|ABC-type uptake permease activity|ATP-binding cassette (ABC) transporter activity|ABC transporter|ABC-type transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/21273|https://github.com/geneontology/go-ontology/issues/20529					pg	2019-06-25T19:08:14Z				Wikipedia:ATP-binding_cassette_transporter|Reactome:R-HSA-5387389|TC:3.A.1|Reactome:R-HSA-5362459|Reactome:R-HSA-5683325|Reactome:R-HSA-266070|Reactome:R-HSA-5223313|Reactome:R-HSA-9661405		molecular_function											owl:Class	
GO:0008664	biolink:NamedThing	2'-5'-RNA ligase activity	Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another.	got7fsn_ti	2'-5' RNA ligase activity													molecular_function											owl:Class	
GO:0008452	biolink:NamedThing	RNA ligase activity	Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another.	got7fsn_ti														molecular_function											owl:Class	
GO:0102220	biolink:NamedThing	hydrogenase activity (NAD+, ferredoxin)	Catalysis of the reaction: 2 dihydrogen + NAD + 2 an oxidized ferredoxin = NADH + 3 H+ + 2 a reduced ferredoxin.	got7fsn_ti												MetaCyc:RXN-12215|EC:1.12.1.4|RHEA:30279		molecular_function											owl:Class	
GO:0009309	biolink:NamedThing	amine biosynthetic process	The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.	got7fsn_ti	amine biosynthesis|amine formation|amine anabolism|amine synthesis													biological_process											owl:Class	
GO:0043204	biolink:NamedThing	perikaryon	The portion of the cell soma (neuronal cell body) that excludes the nucleus.	got7fsn_ti	cell soma cytoplasm													cellular_component											owl:Class	
GO:0008343	biolink:NamedThing	adult feeding behavior	Feeding behavior in a fully developed and mature organism.	got7fsn_ti	adult feeding behaviour				See also the biological process term 'feeding behavior ; GO:0007631'.									biological_process											owl:Class	
GO:0004914	biolink:NamedThing	interleukin-5 receptor activity	Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-5 receptor activity|IL-5R													molecular_function											owl:Class	
GO:0018934	biolink:NamedThing	nitrilotriacetate metabolic process	The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment.	got7fsn_ti	nitrilotriacetate metabolism											UM-BBD_pathwayID:nta		biological_process											owl:Class	
GO:0102840	biolink:NamedThing	1-18:2-2-16:3-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:3-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8301|EC:1.14.19.35		molecular_function											owl:Class	
GO:0060223	biolink:NamedThing	retinal rod cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.	got7fsn_ti														biological_process											owl:Class	
GO:0022803	biolink:NamedThing	passive transmembrane transporter activity	Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.	got7fsn_ti	uniporter activity z|facilitated diffusion|porters										GO:0022814	Reactome:R-HSA-429767|Wikipedia:Facilitated_diffusion		molecular_function											owl:Class	
GO:0051432	biolink:NamedThing	BH1 domain binding	Binding to a BH1 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.	got7fsn_ti														molecular_function											owl:Class	
GO:0102713	biolink:NamedThing	gibberellin A25 hydroxylase activity	Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate(2-) + O2 <=> gibberellin A46 + succinate(2-) + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-6543		molecular_function											owl:Class	
GO:0071535	biolink:NamedThing	RING-like zinc finger domain binding	Binding to a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain.	got7fsn_ti							mah	2010-01-08T03:10:14Z						molecular_function											owl:Class	
GO:0050352	biolink:NamedThing	trimethylamine-oxide aldolase activity	Catalysis of the reaction: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde.	got7fsn_ti	trimethylamine-N-oxide formaldehyde-lyase activity|trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming)|trimethylamine N-oxide aldolase activity|trimethylamine N-oxide demethylase activity|trimethylamine N-oxide formaldehyde-lyase activity											KEGG_REACTION:R02512|MetaCyc:TRIMETHYLAMINE-OXIDE-ALDOLASE-RXN|UM-BBD_reactionID:r1409|EC:4.1.2.32|RHEA:20217		molecular_function											owl:Class	
GO:1990690	biolink:NamedThing	Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane	The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.	got7fsn_ti	medial-Golgi cisterna-derived vesicle fusion with cis-Golgi cisterna membrane						bhm	2015-03-12T09:47:03Z						biological_process											owl:Class	
GO:0038185	biolink:NamedThing	intracellular bile acid receptor signaling pathway	A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	nuclear bile acid receptor signaling pathway						bf	2013-05-16T11:08:02Z						biological_process											owl:Class	
GO:0015571	biolink:NamedThing	N-acetylgalactosamine transmembrane transporter activity	Enables the transfer of N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.	got7fsn_ti	N-acetylgalactosamine permease activity										GO:0015590			molecular_function											owl:Class	
GO:0044534	biolink:NamedThing	envenomation resulting in modulation of apoptotic process in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of apoptosis in the bitten organism.	got7fsn_ti							jl	2012-03-21T11:39:44Z						biological_process											owl:Class	
GO:0040008	biolink:NamedThing	regulation of growth	Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.	got7fsn_ti														biological_process											owl:Class	
GO:0103105	biolink:NamedThing	2-oxo-6-methylthiohexanoate aminotransferase activity	Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + a standard alpha amino acid <=> dihomomethionine + a 2-oxo carboxylate.	got7fsn_ti												MetaCyc:RXNQT-4345		molecular_function											owl:Class	
GO:0140681	biolink:NamedThing	histone H3-tri/dimethyl-lysine-36 demethylase activity	Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone H3K36me3 demethylase activity|histone H3K36me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089					pg	2021-07-08T14:12:31Z				RHEA:60236|MetaCyc: RXN-8660|EC:1.14.11.69		molecular_function											owl:Class	
GO:0033355	biolink:NamedThing	ascorbate glutathione cycle	A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH.	got7fsn_ti	hydrogen peroxide detoxification											MetaCyc:PWY-2261		biological_process											owl:Class	
GO:0019852	biolink:NamedThing	L-ascorbic acid metabolic process	The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.	got7fsn_ti	vitamin C metabolism|vitamin C metabolic process|ascorbate metabolism|L-ascorbic acid metabolism|ascorbate metabolic process													biological_process											owl:Class	
GO:0031708	biolink:NamedThing	endothelin B receptor binding	Binding to an endothelin B receptor.	got7fsn_ti	endothelin B receptor ligand													molecular_function											owl:Class	
GO:0003977	biolink:NamedThing	UDP-N-acetylglucosamine diphosphorylase activity	Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine.	got7fsn_ti	UDP-GlcNAc pyrophosphorylase activity|N-acetylglucosamine-1-phosphate uridyltransferase activity|uridine diphosphate-N-acetylglucosamine pyrophosphorylase activity|GlmU uridylyltransferase activity|UDP-acetylglucosamine pyrophosphorylase activity|UTP:2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate uridylyltransferase activity|acetylglucosamine 1-phosphate uridylyltransferase|UDP-N-acetylglucosamine pyrophosphorylase activity|UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase activity|uridine diphosphoacetylglucosamine pyrophosphorylase activity|uridine diphosphoacetylglucosamine phosphorylase activity											MetaCyc:NAG1P-URIDYLTRANS-RXN|RHEA:13509|Reactome:R-HSA-446204|EC:2.7.7.23|KEGG_REACTION:R00416		molecular_function											owl:Class	
GO:0018818	biolink:NamedThing	acetylene hydratase activity	Catalysis of the reaction: acetaldehyde = acetylene + H(2)O.	got7fsn_ti	AH|AHy|acetaldehyde hydro-lyase activity											MetaCyc:R141-RXN|RHEA:17885|KEGG_REACTION:R05380|UM-BBD_reactionID:r0591|EC:4.2.1.112		molecular_function											owl:Class	
GO:0075002	biolink:NamedThing	adhesion of symbiont germination tube to host	The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	adhesion of symbiont germination tube to host during symbiotic interaction				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0102617	biolink:NamedThing	oryzalexin C synthase (oryzalexin B dependent) activity	Catalysis of the reaction: oryzalexin B + NAD(P) <=> oryzalexin C + H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-15465		molecular_function											owl:Class	
GO:0004092	biolink:NamedThing	carnitine O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA.	got7fsn_ti	carnitine-acetyl-CoA transferase activity|carnitine acetyl coenzyme A transferase activity|carnitine O-acetyltransferase II activity|carnitine acetylase activity|carnitine acetyltransferase activity|acetylcarnitine transferase activity|carnitine O-acetyltransferase I activity|acetyl-CoA:carnitine O-acetyltransferase activity|CATC|acetyl-CoA-carnitine O-acetyltransferase activity										GO:0004094|GO:0004093	Reactome:R-HSA-390284|MetaCyc:CARNITINE-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.7|Reactome:R-HSA-390291|RHEA:21136|KEGG_REACTION:R02396		molecular_function											owl:Class	
GO:0018153	biolink:NamedThing	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine.	got7fsn_ti												RESID:AA0124		biological_process											owl:Class	
GO:0061130	biolink:NamedThing	pancreatic bud formation	The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.	got7fsn_ti							dph	2010-05-17T09:33:40Z						biological_process											owl:Class	
GO:0061114	biolink:NamedThing	branching involved in pancreas morphogenesis	The process in which the branches of the pancreas are generated and organized.	got7fsn_ti							dph	2010-05-05T12:03:04Z						biological_process											owl:Class	
GO:0030894	biolink:NamedThing	replisome	A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.	got7fsn_ti	RC complex|replication-competent complex|DNA synthesome complex											Wikipedia:Replisome		cellular_component											owl:Class	
GO:0006537	biolink:NamedThing	glutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.	got7fsn_ti	glutamic acid biosynthetic process|glutamate biosynthetic process, using glutamate synthase (NADPH)|glutamate biosynthesis|glutamate synthesis|glutamic acid biosynthesis|glutamate anabolism|glutamate biosynthesis, using glutamate synthase (NADPH)|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)|glutamate formation													biological_process											owl:Class	
GO:0071090	biolink:NamedThing	alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.	got7fsn_ti	ITGA2b-ITGB3-FN1-TGM2 complex						mah	2009-11-06T04:46:24Z						cellular_component											owl:Class	
GO:0052391	biolink:NamedThing	induction by symbiont of defense-related host calcium ion flux	The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by symbiont of defense-related host calcium ion flux|upregulation by symbiont of defense-related host calcium ion flux|positive regulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction|up regulation by symbiont of defense-related host calcium ion flux|stimulation by symbiont of defense-related host calcium ion flux|positive regulation by symbiont of defense-related host calcium ion flux|activation by organism of host calcium ion flux|induction by organism of host Ca2+ flux|induction by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction|activation by organism of host Ca2+ flux|up-regulation by symbiont of defense-related host calcium ion flux|positive regulation by organism of defense-related host Ca2+ flux										GO:0052389|GO:0052265|GO:0052065			biological_process											owl:Class	
GO:0034349	biolink:NamedThing	glial cell apoptotic process	Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.	got7fsn_ti	apoptosis of glia|programmed cell death, glial cells|glia programmed cell death by apoptosis|glial cell apoptosis|programmed cell death of glia by apoptosis|glial cell programmed cell death by apoptosis|programmed cell death, glia|apoptosis of glial cells|glia apoptosis|programmed cell death of glial cells by apoptosis													biological_process											owl:Class	
GO:0034798	biolink:NamedThing	fosfomycin 2-L-cysteine ligase activity	Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid.	got7fsn_ti												UM-BBD_reactionID:r1074		molecular_function											owl:Class	
GO:0102066	biolink:NamedThing	alpha-patchoulene synthase activityy	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene.	got7fsn_ti												MetaCyc:RXN-10603		molecular_function											owl:Class	
GO:0004784	biolink:NamedThing	superoxide dismutase activity	Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.	got7fsn_ti	SOD-4|iron superoxide oxidoreductase|Mn, Fe superoxide dismutase|cytocuprein|SOD-3|iron superoxide dismutase activity|ferrisuperoxide dismutase activity|manganese superoxide oxidoreductase|SODS|superoxide dismutase I|Mn-SOD|Fe-SOD|hepatocuprein|SODF|cuprein|SOD-1|SOD-2|hemocuprein|Cu-Zn superoxide dismutase activity|zinc superoxide oxidoreductase|nickel superoxide dismutase activity|superoxide dismutase II|SOD|erythrocuprein|superoxide:superoxide oxidoreductase activity|nickel superoxide oxidoreductase|manganese superoxide dismutase activity|copper, zinc superoxide dismutase activity|Cu,Zn-SOD										GO:0008383|GO:0004785|GO:0008382|GO:0016954	Reactome:R-HSA-3299691|Reactome:R-HSA-1222469|EC:1.15.1.1|MetaCyc:SUPEROX-DISMUT-RXN|Reactome:R-HSA-3299682|Reactome:R-HSA-1222462|Reactome:R-HSA-3299680|RHEA:20696|Reactome:R-HSA-3777112		molecular_function											owl:Class	
GO:0070923	biolink:NamedThing	siRNA loading onto RISC involved in gene silencing by small RNA	The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin gene by small RNA.	got7fsn_ti	chromatin silencing by small RNA, siRNA loading onto RISC|siRNA loading onto RISC involved in chromatin silencing by small RNA	https://github.com/geneontology/go-ontology/issues/22058					mah	2009-09-11T04:01:44Z						biological_process											owl:Class	
GO:0005831	biolink:NamedThing	steroid hormone aporeceptor complex	A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand.	got7fsn_ti														cellular_component											owl:Class	
GO:0080034	biolink:NamedThing	host response to induction by symbiont of tumor, nodule or growth in host	Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:1990745	biolink:NamedThing	EARP complex	A quatrefoil tethering complex required for endocytic recycling.	got7fsn_ti							sp	2015-05-15T10:23:25Z						cellular_component											owl:Class	
GO:0047905	biolink:NamedThing	fructose-6-phosphate phosphoketolase activity	Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O.	got7fsn_ti	D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)|D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (phosphate-acetylating) activity											RHEA:12196|EC:4.1.2.22|MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN		molecular_function											owl:Class	
GO:0052796	biolink:NamedThing	exo-alpha-(2->8)-sialidase activity	Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates.	got7fsn_ti	exo-alpha-2,8-sialidase activity|exo-alpha-(2,8)-sialidase activity											EC:3.2.1.18		molecular_function											owl:Class	
GO:0090465	biolink:NamedThing	arginine homeostasis	Any process involved in the maintenance of an internal steady state of arginine within an organism or cell.	got7fsn_ti							tb	2012-09-24T14:22:02Z						biological_process											owl:Class	
GO:0009408	biolink:NamedThing	response to heat	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	got7fsn_ti	response to heat shock										GO:0006951			biological_process											owl:Class	
GO:0072341	biolink:NamedThing	modified amino acid binding	Binding to a modified amino acid.	got7fsn_ti	amino acid derivative binding						mah	2010-11-04T05:45:32Z						molecular_function											owl:Class	
GO:0001079	biolink:NamedThing	nitrogen catabolite regulation of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter by nitrogen catabolites						krc	2010-10-27T03:29:01Z						biological_process											owl:Class	
GO:0043143	biolink:NamedThing	regulation of translation by machinery localization	Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of translational protein localization|translational machinery localization|regulation of translation by machinery localisation|establishment and maintenance of translational machinery localization|translational protein localization													biological_process											owl:Class	
GO:0001919	biolink:NamedThing	regulation of receptor recycling	Any process that modulates the frequency, rate, or extent of receptor recycling.	got7fsn_ti														biological_process											owl:Class	
GO:0004369	biolink:NamedThing	glycerol-3-phosphate oxidase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2).	got7fsn_ti	L-alpha-glycerophosphate oxidase activity|glycerol-1-phosphate oxidase activity|alpha-glycerophosphate oxidase activity|L-alpha-glycerol-3-phosphate oxidase activity|glycerol phosphate oxidase activity|sn-glycerol-3-phosphate:oxygen 2-oxidoreductase activity											RHEA:18369|EC:1.1.3.21|KEGG_REACTION:R00846|MetaCyc:GLYCEROL-3-PHOSPHATE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0035316	biolink:NamedThing	non-sensory hair organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.	got7fsn_ti	trichome organization and biogenesis|trichome organisation|non-sensory hair organization and biogenesis				See also the fly_anatomy.ontology term 'trichome ; FBbt:00004979'.									biological_process											owl:Class	
GO:0051030	biolink:NamedThing	snRNA transport	The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0038169	biolink:NamedThing	somatostatin receptor signaling pathway	The series of molecular signals generated as a consequence of a somatostatin receptor (SSTR) binding to one of its physiological ligands and transmitting the signal to a heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	SSTR signaling pathway|SST receptor signaling pathway				In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'.		bf	2012-06-12T10:30:01Z						biological_process											owl:Class	
GO:0001052	biolink:NamedThing	plastid PEP RNA polymerase core enzyme binding	Binding to a bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit.	got7fsn_ti							krc	2010-09-23T02:49:31Z						molecular_function											owl:Class	
GO:0001000	biolink:NamedThing	bacterial-type RNA polymerase core enzyme binding	Binding to a bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit.	got7fsn_ti	eubacterial-type RNA polymerase core enzyme binding				Should omega be included here?		krc	2010-08-17T04:59:00Z						molecular_function											owl:Class	
GO:0047745	biolink:NamedThing	chlorogenate hydrolase activity	Catalysis of the reaction: chlorogenate + H(2)O = (-)-quinate + cis-caffeate + H(+).	got7fsn_ti	chlorogenic acid esterase activity|chlorogenase activity											EC:3.1.1.42|MetaCyc:CHLOROGENATE-HYDROLASE-RXN|KEGG_REACTION:R02997|RHEA:20689		molecular_function											owl:Class	
GO:1901564	biolink:NamedThing	organonitrogen compound metabolic process	The chemical reactions and pathways involving organonitrogen compound.	got7fsn_ti	organonitrogen compound metabolism						pr	2012-11-04T15:17:52Z						biological_process											owl:Class	
GO:0090215	biolink:NamedThing	regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	got7fsn_ti							tb	2010-01-12T10:00:45Z						biological_process											owl:Class	
GO:0016864	biolink:NamedThing	intramolecular oxidoreductase activity, transposing S-S bonds	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears.	got7fsn_ti	intramolecular isomerase activity, transposing S-S bonds											EC:5.3.4.-		molecular_function											owl:Class	
GO:0039576	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host JAK1 (Janus Kinase 1).	got7fsn_ti	suppression by virus of tyrosine phosphorylation of host STAT protein|suppression by virus of host janus kinase 1 activity|inhibition of host JAK activity by virus|negative regulation by virus of host JAK|viral inhibition of tyrosine phosphorylation of host STAT protein|negative regulation by virus of tyrosine phosphorylation of host STAT protein|suppression by virus of host JAK1 activity	https://github.com/geneontology/go-ontology/issues/21963					bf				GO:0039515	VZ:784		biological_process											owl:Class	
GO:0034997	biolink:NamedThing	alphav-beta5 integrin-vitronectin complex	A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin.	got7fsn_ti	ITGAV-ITGB5-VTN complex													cellular_component											owl:Class	
GO:0051960	biolink:NamedThing	regulation of nervous system development	Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.	got7fsn_ti														biological_process											owl:Class	
GO:1990747	biolink:NamedThing	pancreatic trypsinogen secretion	The regulated release of trypsinogen from the cells of the exocrine pancreas.	got7fsn_ti	pancreatic trypsinogen release						sl	2015-05-15T17:41:25Z						biological_process											owl:Class	
GO:0008686	biolink:NamedThing	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+).	got7fsn_ti												EC:4.1.99.12|MetaCyc:DIOHBUTANONEPSYN-RXN|KEGG_REACTION:R07281|RHEA:18457		molecular_function											owl:Class	
GO:0102359	biolink:NamedThing	daphnetin 4-O-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 7,8-dihydroxycoumarin <=> UDP + 4-O- beta -D-glucosyl-daphnetin + H+.	got7fsn_ti												MetaCyc:RXN-13450|EC:2.4.1.126		molecular_function											owl:Class	
GO:0047139	biolink:NamedThing	glutathione-homocystine transhydrogenase activity	Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine.	got7fsn_ti	glutathione:homocystine oxidoreductase activity											EC:1.8.4.1|MetaCyc:1.8.4.1-RXN|RHEA:11464		molecular_function											owl:Class	
GO:0047405	biolink:NamedThing	pyrimidine-5'-nucleotide nucleosidase activity	Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine.	got7fsn_ti	Pyr5N activity|pyrimidine nucleotide N-ribosidase activity|pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase activity											MetaCyc:3.2.2.10-RXN|RHEA:13425|EC:3.2.2.10		molecular_function											owl:Class	
GO:0000492	biolink:NamedThing	box C/D snoRNP assembly	The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex.	got7fsn_ti	box C/D small nucleolar ribonucleoprotein complex assembly													biological_process											owl:Class	
GO:0000491	biolink:NamedThing	small nucleolar ribonucleoprotein complex assembly	The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex.	got7fsn_ti	snoRNP assembly													biological_process											owl:Class	
GO:0033522	biolink:NamedThing	histone H2A ubiquitination	The modification of histone H2A by addition of one or more ubiquitin groups.	got7fsn_ti														biological_process											owl:Class	
GO:0071501	biolink:NamedThing	cellular response to sterol depletion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti	cellular sterol depletion response						mah	2009-12-18T02:54:14Z						biological_process											owl:Class	
GO:0070698	biolink:NamedThing	type I activin receptor binding	Binding to a type I activin receptor.	got7fsn_ti							mah	2009-06-04T04:15:21Z						molecular_function											owl:Class	
GO:0047562	biolink:NamedThing	3-hydroxyaspartate aldolase activity	Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate.	got7fsn_ti	erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming)|erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase activity|erythro-3-hydroxy-L(s)-aspartate glyoxylate-lyase activity|erythro-beta-hydroxyaspartate aldolase activity|erythro-beta-hydroxyaspartate glycine-lyase activity											MetaCyc:3-HYDROXYASPARTATE-ALDOLASE-RXN|KEGG_REACTION:R00478|EC:4.1.3.14|RHEA:14377		molecular_function											owl:Class	
GO:0034741	biolink:NamedThing	APC-tubulin-IQGAP1 complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization.	got7fsn_ti	60S APC complex				Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0005655	biolink:NamedThing	nucleolar ribonuclease P complex	A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.	got7fsn_ti	nucleolar RNase P complex													cellular_component											owl:Class	
GO:0043975	biolink:NamedThing	histone H3-K36 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone.	got7fsn_ti	histone H3 acetylation at K36|histone H3K36 acetylation													biological_process											owl:Class	
GO:0045998	biolink:NamedThing	positive regulation of ecdysteroid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.	got7fsn_ti	stimulation of ecdysteroid biosynthetic process|positive regulation of ecdysteroid synthesis|up-regulation of ecdysteroid biosynthetic process|up regulation of ecdysteroid biosynthetic process|upregulation of ecdysteroid biosynthetic process|positive regulation of ecdysteroid anabolism|activation of ecdysteroid biosynthetic process|positive regulation of ecdysteroid formation|positive regulation of ecdysteroid biosynthesis													biological_process											owl:Class	
GO:0086041	biolink:NamedThing	voltage-gated potassium channel activity involved in SA node cell action potential depolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated potassium channel activity involved in sinus node cell action potential depolarization|voltage-gated potassium channel activity involved in sinoatrial node cell action potential depolarization|voltage-gated potassium channel activity involved in SAN cell action potential depolarization						tb	2011-11-11T03:37:42Z						molecular_function											owl:Class	
GO:1900351	biolink:NamedThing	regulation of methanofuran biosynthetic process	Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process.	got7fsn_ti	regulation of methanofuran biosynthesis						tt	2012-04-06T02:13:51Z						biological_process											owl:Class	
GO:0042068	biolink:NamedThing	regulation of pteridine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine.	got7fsn_ti	regulation of pteridine metabolism													biological_process											owl:Class	
GO:0102942	biolink:NamedThing	3,5-dimethoxyphenol O-methyltransferase activity	Catalysis of the reaction: 3,5-dimethoxyphenol + S-adenosyl-L-methionine  = H+ + 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-9022		molecular_function											owl:Class	
GO:0045004	biolink:NamedThing	DNA replication proofreading	Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.	got7fsn_ti														biological_process											owl:Class	
GO:0044322	biolink:NamedThing	endoplasmic reticulum quality control compartment	A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.	got7fsn_ti	ER-derived quality control compartment|ERQC|ER quality control compartment						jl	2010-08-03T01:12:59Z						cellular_component											owl:Class	
GO:0102105	biolink:NamedThing	demethoxycurcumin synthase activity from feruloylacetyl-CoA	Catalysis of the reaction: feruloylacetyl-CoA + 4-coumaryl-CoA + H2O = demethoxycurcumin + 2 coenzyme A + carbon dioxide.	got7fsn_ti												RHEA:35139|EC:2.3.1.219|MetaCyc:RXN-11225		molecular_function											owl:Class	
GO:0002566	biolink:NamedThing	somatic diversification of immune receptors via somatic mutation	The process in which immune receptor genes are diversified through somatic mutation.	got7fsn_ti														biological_process											owl:Class	
GO:0035613	biolink:NamedThing	RNA stem-loop binding	Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.	got7fsn_ti	RNA hairpin binding|RNA hairpin loop binding						bf	2010-11-26T10:41:49Z						molecular_function											owl:Class	
GO:0035685	biolink:NamedThing	helper T cell diapedesis	The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.	got7fsn_ti	helper T-cell diapedesis|T-helper cell diapedesis						bf	2011-02-23T01:11:52Z						biological_process											owl:Class	
GO:0047024	biolink:NamedThing	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH.	got7fsn_ti	3-beta-HSD activity|3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity|dehydrogenase, 3beta,20alpha-hydroxy steroid|3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity|3beta,20alpha-hydroxysteroid oxidoreductase activity|progesterone reductase activity|3beta(or 20alpha)-hydroxysteroid dehydrogenase activity											MetaCyc:1.1.1.210-RXN|RHEA:16297|KEGG_REACTION:R04344|EC:1.1.1.210		molecular_function											owl:Class	
GO:0031049	biolink:NamedThing	programmed DNA elimination	The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate.	got7fsn_ti														biological_process											owl:Class	
GO:0006623	biolink:NamedThing	protein targeting to vacuole	The process of directing proteins towards the vacuole, usually using signals contained within the protein.	got7fsn_ti	vacuolar protein sorting|protein-vacuole targeting|protein vacuolar targeting|protein-vacuolar targeting													biological_process											owl:Class	
GO:0031786	biolink:NamedThing	type 1B melatonin receptor binding	Binding to a type 1B melatonin receptor.	got7fsn_ti	type 1B melatonin receptor ligand													molecular_function											owl:Class	
GO:0055029	biolink:NamedThing	nuclear DNA-directed RNA polymerase complex	A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0052832	biolink:NamedThing	inositol monophosphate 3-phosphatase activity	Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate.	got7fsn_ti							ai	2011-11-29T11:00:09Z				RHEA:30739|Reactome:R-HSA-1855210|MetaCyc:MYO-INOSITOL-1OR-4-MONOPHOSPHATASE-RXN|EC:3.1.3.25		molecular_function											owl:Class	
GO:0002416	biolink:NamedThing	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor	The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals.	got7fsn_ti	IgG antibody transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor|IgG immunoglobulin transcytosis in epithelial cells mediated by neonatal immunoglobulin receptor													biological_process											owl:Class	
GO:0002414	biolink:NamedThing	immunoglobulin transcytosis in epithelial cells	The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other.	got7fsn_ti														biological_process											owl:Class	
GO:0001010	biolink:NamedThing	RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity	The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions.	got7fsn_ti	transcription factor activity, sequence-specific DNA-binding transcription factor recruiting|transcription factor activity, sequence-specific DNA binding transcription factor recruiting|sequence-specific DNA binding transcription factor recruiting transcription factor activity						krc	2010-08-18T06:46:33Z						molecular_function											owl:Class	
GO:0106365	biolink:NamedThing	beta-carotene isomerase activity	Catalyzes the reaction: all-trans-beta-carotene = 9-cis-beta-carotene.	got7fsn_ti							hjd	2021-02-16T15:32:24Z				EC:5.2.1.14|RHEA:34455		molecular_function											owl:Class	
GO:0009305	biolink:NamedThing	protein biotinylation	The addition of biotin (vitamin B7 / vitamin H) to a protein amino acid.	got7fsn_ti	protein amino acid biotinylation													biological_process											owl:Class	
GO:0050087	biolink:NamedThing	mannitol dehydrogenase (cytochrome) activity	Catalysis of the reaction: 2 [Fe(III)cytochrome c] + D-mannitol = 2 [Fe(II)cytochrome c] + D-fructose + 2 H+.	got7fsn_ti	D-mannitol:ferricytochrome-c 2-oxidoreductase activity|polyol dehydrogenase activity											MetaCyc:MANNITOL-DEHYDROGENASE-CYTOCHROME-RXN|RHEA:17597|EC:1.1.2.2		molecular_function											owl:Class	
GO:0016898	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule.	got7fsn_ti												EC:1.1.2.-		molecular_function											owl:Class	
GO:0018454	biolink:NamedThing	acetoacetyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.	got7fsn_ti	acetoacetyl coenzyme A reductase activity|D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity|(R)-3-hydroxyacyl-CoA dehydrogenase activity|short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity|NADP-linked acetoacetyl CoA reductase activity|(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity|hydroxyacyl coenzyme-A dehydrogenase activity|D-3-hydroxyacyl-CoA reductase activity|beta-ketoacyl-CoA reductase|NADPH:acetoacetyl-CoA reductase activity											RHEA:22256|UM-BBD_reactionID:r0202|MetaCyc:RXN-7698|EC:1.1.1.36		molecular_function											owl:Class	
GO:0046778	biolink:NamedThing	modification by virus of host mRNA processing	Any viral process that interferes with the processing of mRNA in the host cell.	got7fsn_ti	viral perturbation of host mRNA processing													biological_process											owl:Class	
GO:0050684	biolink:NamedThing	regulation of mRNA processing	Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.	got7fsn_ti														biological_process											owl:Class	
GO:0030756	biolink:NamedThing	isoorientin 3'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin.	got7fsn_ti	isoorientin 3'-methyltransferase activity|S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase activity											EC:2.1.1.78|KEGG_REACTION:R03731|RHEA:24096|MetaCyc:ISOORIENTIN-3-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0005034	biolink:NamedThing	osmosensor activity	Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.	got7fsn_ti														molecular_function											owl:Class	
GO:0048100	biolink:NamedThing	wing disc anterior/posterior pattern formation	The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.	got7fsn_ti														biological_process											owl:Class	
GO:0032783	biolink:NamedThing	super elongation complex	A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae.	got7fsn_ti	ELL-EAF complex|ELL-EAF-EBP complex	https://github.com/geneontology/go-ontology/issues/17203												cellular_component											owl:Class	
GO:0021507	biolink:NamedThing	posterior neuropore closure	The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.	got7fsn_ti														biological_process											owl:Class	
GO:0030244	biolink:NamedThing	cellulose biosynthetic process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.	got7fsn_ti	cellulose biosynthesis|cellulose anabolism|cellulose synthesis|cellulose formation										GO:0016178	MetaCyc:PWY-1001		biological_process											owl:Class	
GO:0061073	biolink:NamedThing	ciliary body morphogenesis	The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.	got7fsn_ti							dph	2010-03-16T10:55:19Z						biological_process											owl:Class	
GO:0106092	biolink:NamedThing	glial cell projection elongation involved in axon ensheathment	The extension of a glial cell process or projection to wrap around an axon.	got7fsn_ti							hjd	2018-01-26T19:43:00Z						biological_process											owl:Class	
GO:0106091	biolink:NamedThing	glial cell projection elongation	The process of creating an elongation or projection from a glial cell.	got7fsn_ti							hjd	2018-01-26T19:40:19Z						biological_process											owl:Class	
GO:0047428	biolink:NamedThing	arylacetonitrilase activity	Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3.	got7fsn_ti	arylacetonitrile aminohydrolase activity											MetaCyc:3.5.5.5-RXN|RHEA:20657|EC:3.5.5.5		molecular_function											owl:Class	
GO:0102082	biolink:NamedThing	demethylrebeccamycin--D-glucose O-methyltransferase activity	Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine  <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.164|MetaCyc:RXN-10847|RHEA:27353		molecular_function											owl:Class	
GO:0072432	biolink:NamedThing	response to G1 DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling.	got7fsn_ti	response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|mitotic cell cycle G1/S transition DNA damage checkpoint effector process						mah	2010-12-08T04:38:04Z						biological_process											owl:Class	
GO:0007489	biolink:NamedThing	maintenance of imaginal histoblast diploidy	The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells.	got7fsn_ti														biological_process											owl:Class	
GO:0044641	biolink:NamedThing	envenomation resulting in positive regulation of complement activation, lectin pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism.	got7fsn_ti							jl	2012-07-11T11:50:23Z						biological_process											owl:Class	
GO:0006615	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane, docking	The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting.	got7fsn_ti	SRP-dependent cotranslational membrane targeting, docking|SRP-dependent cotranslational protein-membrane targeting, docking|protein docking during SRP-dependent cotranslational protein targeting to membrane													biological_process											owl:Class	
GO:0022615	biolink:NamedThing	protein to membrane docking	The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere.	got7fsn_ti	protein-membrane docking													biological_process											owl:Class	
GO:0071282	biolink:NamedThing	cellular response to iron(II) ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.	got7fsn_ti	cellular response to iron(II)						mah	2009-12-10T03:57:49Z						biological_process											owl:Class	
GO:0010040	biolink:NamedThing	response to iron(II) ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.	got7fsn_ti	response to iron(II)													biological_process											owl:Class	
GO:0030502	biolink:NamedThing	negative regulation of bone mineralization	Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.	got7fsn_ti	inhibition of bone mineralization|down regulation of bone mineralization|downregulation of bone mineralization|down-regulation of bone mineralization													biological_process											owl:Class	
GO:0030279	biolink:NamedThing	negative regulation of ossification	Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.	got7fsn_ti	downregulation of ossification|negative regulation of bone formation|down-regulation of ossification|negative regulation of bone biosynthesis|down regulation of ossification|inhibition of ossification													biological_process											owl:Class	
GO:0004765	biolink:NamedThing	shikimate kinase activity	Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+).	got7fsn_ti	shikimate kinase (phosphorylating)|ATP:shikimate 3-phosphotransferase activity|shikimate kinase II											KEGG_REACTION:R02412|MetaCyc:SHIKIMATE-KINASE-RXN|RHEA:13121|EC:2.7.1.71		molecular_function											owl:Class	
GO:0000824	biolink:NamedThing	inositol tetrakisphosphate 3-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.	got7fsn_ti	EC:2.7.1.151|IpmK|inositol 1,4,5,6-tetrakisphosphate 3-kinase activity|inositol polyphosphate multikinase activity|1D-myo-inositol-tetrakisphosphate 3-kinase activity											RHEA:11856|Reactome:R-HSA-1855185		molecular_function											owl:Class	
GO:0051765	biolink:NamedThing	inositol tetrakisphosphate kinase activity	Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP.	got7fsn_ti														molecular_function											owl:Class	
GO:0004829	biolink:NamedThing	threonine-tRNA ligase activity	Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).	got7fsn_ti	threonyl-transfer ribonucleic acid synthetase activity|L-threonine:tRNAThr ligase (AMP-forming)|threonyl ribonucleic synthetase activity|threonine-transfer ribonucleate synthetase activity|TRS|threonine translase activity|threonyl-tRNA synthetase activity|threonyl-transfer ribonucleate synthetase activity|threonyl-transfer RNA synthetase activity											EC:6.1.1.3|RHEA:24624|Reactome:R-HSA-380002|MetaCyc:THREONINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380201		molecular_function											owl:Class	
GO:0046484	biolink:NamedThing	oxazole or thiazole metabolic process	The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.	got7fsn_ti	oxazole or thiazole metabolism													biological_process											owl:Class	
GO:0044077	biolink:NamedThing	modulation by symbiont of host receptor-mediated endocytosis	The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.	got7fsn_ti	modulation of host receptor-mediated endocytosis by symbiont|regulation by symbiont of host receptor-mediated endocytosis													biological_process											owl:Class	
GO:0044587	biolink:NamedThing	cellopentaose binding	Binding to a cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.	got7fsn_ti							jl	2012-04-24T04:57:01Z						molecular_function											owl:Class	
GO:0032163	biolink:NamedThing	hyphal septin band	A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.	got7fsn_ti														cellular_component											owl:Class	
GO:0071153	biolink:NamedThing	G-protein alpha(o)-synembrin complex	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein.	got7fsn_ti	Ric-8A G(o) alpha-2 subunit complex|Ric-8A G(o) alpha-1 subunit complex						mah	2009-11-16T04:55:00Z						cellular_component											owl:Class	
GO:0033107	biolink:NamedThing	Cvt vesicle	A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p).	got7fsn_ti	cytoplasm-to-vacuole targeting vesicle|cytoplasm to vacuole targeting vesicle													cellular_component											owl:Class	
GO:0004603	biolink:NamedThing	phenylethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.	got7fsn_ti	S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase activity|noradrenaline N-methyltransferase activity|norepinephrine methyltransferase activity|norepinephrine N-methyltransferase activity|phenethanolamine methyltransferase activity|noradrenalin N-methyltransferase activity|phenethanolamine N-methyltransferase activity											RHEA:12176|MetaCyc:2.1.1.28-RXN|EC:2.1.1.28|Reactome:R-HSA-209903		molecular_function											owl:Class	
GO:0047289	biolink:NamedThing	galactosyldiacylglycerol alpha-2,3-sialyltransferase activity	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+).	got7fsn_ti	CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase activity											RHEA:11664|KEGG_REACTION:R03468|MetaCyc:2.4.99.5-RXN|EC:2.4.99.5		molecular_function											owl:Class	
GO:0009739	biolink:NamedThing	response to gibberellin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.	got7fsn_ti	response to gibberellin stimulus|response to gibberellic acid stimulus													biological_process											owl:Class	
GO:0150094	biolink:NamedThing	amyloid-beta clearance by cellular catabolic process	The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.	got7fsn_ti	amyloid-beta clearance by phagocytosis						bc	2018-08-16T14:38:09Z						biological_process											owl:Class	
GO:1990583	biolink:NamedThing	phospholipase D activator activity	Increases the activity of the enzyme phospholipase D.	got7fsn_ti							sl	2014-12-10T21:04:46Z						molecular_function											owl:Class	
GO:0033917	biolink:NamedThing	exo-poly-alpha-galacturonosidase activity	Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate.	got7fsn_ti	exopolygalacturanosidase activity|exopolygalacturonosidase activity											EC:3.2.1.82|RHEA:56232|MetaCyc:3.2.1.82-RXN		molecular_function											owl:Class	
GO:0031584	biolink:NamedThing	activation of phospholipase D activity	Any process that initiates the activity of inactive phospholipase D.	got7fsn_ti														biological_process											owl:Class	
GO:0010518	biolink:NamedThing	positive regulation of phospholipase activity	Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.	got7fsn_ti														biological_process											owl:Class	
GO:0072027	biolink:NamedThing	connecting tubule development	The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct.	got7fsn_ti	connecting duct development						mah	2010-01-25T02:42:05Z						biological_process											owl:Class	
GO:0008448	biolink:NamedThing	N-acetylglucosamine-6-phosphate deacetylase activity	Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.	got7fsn_ti	acetylglucosamine phosphate deacetylase activity|N-acetyl-D-glucosamine-6-phosphate amidohydrolase activity|2-acetamido-2-deoxy-D-glucose-6-phosphate amidohydrolase activity|acetylaminodeoxyglucosephosphate acetylhydrolase activity											EC:3.5.1.25|Reactome:R-HSA-6803789|MetaCyc:NAG6PDEACET-RXN|RHEA:22936		molecular_function											owl:Class	
GO:0022033	biolink:NamedThing	telencephalon microglial cell migration	The orderly movement of microglial cells through the telencephalon.	got7fsn_ti														biological_process											owl:Class	
GO:0002033	biolink:NamedThing	angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure	The process that increases the diameter of a blood vessel via the renin-angiotensin system.	got7fsn_ti	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0005109	biolink:NamedThing	frizzled binding	Binding to a frizzled (fz) receptor.	got7fsn_ti	fz2 binding|frizzled-2 ligand|fz ligand|fz2 ligand|frizzled ligand|frizzled-2 binding|fz binding										GO:0005110			molecular_function											owl:Class	
GO:0047101	biolink:NamedThing	2-oxoisovalerate dehydrogenase (acylating) activity	Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA.	got7fsn_ti	3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)|2-oxoisovalerate dehydrogenase activity											EC:1.2.1.25|MetaCyc:1.2.1.25-RXN|RHEA:13997		molecular_function											owl:Class	
GO:0034076	biolink:NamedThing	cucurbitadienol synthase activity	Catalysis of the reaction: oxidosqualene = cucurbitadienol.	got7fsn_ti														molecular_function											owl:Class	
GO:0072270	biolink:NamedThing	metanephric short nephron development	The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.	got7fsn_ti							mah	2010-03-30T03:15:18Z						biological_process											owl:Class	
GO:0033755	biolink:NamedThing	sulfur oxygenase/reductase activity	Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+.	got7fsn_ti	SOR|sulfur oxygenase activity|sulphur oxygenase/reductase activity|sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming) activity											EC:1.13.11.55|RHEA:13957|MetaCyc:1.13.11.55-RXN		molecular_function											owl:Class	
GO:0106185	biolink:NamedThing	histone H3-K37 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 37 of the histone.	got7fsn_ti	histone H3 K37 methylation|histone H3K37me|histone lysine H3 K37 methylation						hjd	2019-04-24T14:36:23Z						biological_process											owl:Class	
GO:0075111	biolink:NamedThing	suppression by symbiont of host receptor-mediated signal transduction	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host receptor-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont receptor-mediated signal transduction ; GO:0075080".									biological_process											owl:Class	
GO:0019124	biolink:NamedThing	peptidyl-isoleucine racemization	The racemization of peptidyl-isoleucine.	got7fsn_ti											GO:0018088|GO:0018370	RESID:AA0192		biological_process											owl:Class	
GO:0071154	biolink:NamedThing	G-protein alpha(i)1-synembrin complex	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein.	got7fsn_ti	Ric-8A G(i) alpha-2 subunit complex|Ric-8A G(i) alpha-1 subunit complex						mah	2009-11-16T04:57:46Z						cellular_component											owl:Class	
GO:0021721	biolink:NamedThing	superior olivary nucleus structural organization	The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	got7fsn_ti	superior olivary nucleus structural organisation													biological_process											owl:Class	
GO:0047476	biolink:NamedThing	3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity	Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP.	got7fsn_ti	3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)|3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase activity|DHCA-CoA ligase activity|3alpha,7alpha-dihydroxy-5beta-cholestanate-CoA ligase activity											RHEA:21776|MetaCyc:6.2.1.28-RXN|EC:6.2.1.28		molecular_function											owl:Class	
GO:1990153	biolink:NamedThing	maintenance of protein localization to heterochromatin	A process in which a protein is maintained in a location in telomeric heterochromatin.	got7fsn_ti	maintenance of protein location in heterochromatin|maintenance of protein localisation to heterochromatin						mah	2013-07-31T15:11:37Z						biological_process											owl:Class	
GO:1902509	biolink:NamedThing	methionine-importing complex	A protein complex which is capable of methionine-importing activity.	got7fsn_ti	methionine importer complex|methionine importing complex						pr	2013-11-15T10:42:41Z						cellular_component											owl:Class	
GO:0001829	biolink:NamedThing	trophectodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.	got7fsn_ti	trophectoderm cell differentiation				See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.									biological_process											owl:Class	
GO:0004664	biolink:NamedThing	prephenate dehydratase activity	Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2.	got7fsn_ti	prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming)|prephenate hydro-lyase (decarboxylating)											EC:4.2.1.51|MetaCyc:PREPHENATEDEHYDRAT-RXN|RHEA:21648		molecular_function											owl:Class	
GO:0042587	biolink:NamedThing	glycogen granule	Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface.	got7fsn_ti	glycogen particle											NIF_Subcellular:sao1081228141		cellular_component											owl:Class	
GO:0070225	biolink:NamedThing	sulfide dehydrogenase activity	Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S + reduced cytochrome c.	got7fsn_ti	sulphide dehydrogenase activity|flavocytochrome c sulfide dehydrogenase activity											EC:1.8.2.3|RHEA:30223|MetaCyc:RXN-8156		molecular_function											owl:Class	
GO:0031973	biolink:NamedThing	chromoplast intermembrane space	The region between the inner and outer lipid bilayers of a chromoplast envelope.	got7fsn_ti	chromoplast envelope lumen													cellular_component											owl:Class	
GO:0043833	biolink:NamedThing	methylamine-specific methylcobalamin:coenzyme M methyltransferase activity	Catalysis of the reaction: a methylated methylamine corrinoid protein + coenzyme M = a methylamine corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.	got7fsn_ti	monomethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|methylamine-specific methylcobalamin:CoM methyltransferase activity|methylcobamide:CoM methyltransferase activity|methylcobamide:coenzyme M methyltransferase activity|methylcobamide:CoM methyltransferase II isozyme A				This function is the second step in the pathway of methanogenesis from monomethylamine, dimethylamine and trimethylamine.							MetaCyc:RXN-8099|EC:2.1.1.247|MetaCyc:RXN-8103|MetaCyc:RXN-8101		molecular_function											owl:Class	
GO:0034799	biolink:NamedThing	dihydride TNP tautomerase activity	Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form).	got7fsn_ti												UM-BBD_reactionID:r1070		molecular_function											owl:Class	
GO:0008953	biolink:NamedThing	penicillin amidase activity	Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.	got7fsn_ti	alpha-acylamino-beta-lactam acylhydrolase activity|novozym 217|penicillin amidohydrolase activity|benzylpenicillin acylase activity|penicillin acylase activity|semacylase activity|palmitoleoyl [acyl-carrier protein]-dependent acyltransferase activity|ampicillin acylase activity											EC:3.5.1.11|RHEA:18693|MetaCyc:PENICILLIN-AMIDASE-RXN		molecular_function											owl:Class	
GO:0008499	biolink:NamedThing	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP.	got7fsn_ti	beta3Gal-Ts activity|UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity|beta-1,3-GalTase activity|UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase activity											Reactome:R-HSA-914010|Reactome:R-HSA-9603989		molecular_function											owl:Class	
GO:0035902	biolink:NamedThing	response to immobilization stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.	got7fsn_ti	response to restraint stress|response to immobilisation stress						bf	2011-06-22T09:45:50Z						biological_process											owl:Class	
GO:0007004	biolink:NamedThing	telomere maintenance via telomerase	The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.	got7fsn_ti	telomerase-dependent telomere maintenance													biological_process											owl:Class	
GO:0010833	biolink:NamedThing	telomere maintenance via telomere lengthening	Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0102776	biolink:NamedThing	UDP-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-7828		molecular_function											owl:Class	
GO:0014057	biolink:NamedThing	positive regulation of acetylcholine secretion, neurotransmission	Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.	got7fsn_ti	upregulation of acetylcholine secretion|up regulation of acetylcholine secretion|up-regulation of acetylcholine secretion|activation of acetylcholine secretion|stimulation of acetylcholine secretion													biological_process											owl:Class	
GO:0033254	biolink:NamedThing	vacuolar transporter chaperone complex	A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p.	got7fsn_ti	VTC complex													cellular_component											owl:Class	
GO:0010217	biolink:NamedThing	cellular aluminum ion homeostasis	Any process involved in the maintenance of an internal steady state of aluminum ions at the level of a cell.	got7fsn_ti	cellular aluminium ion homeostasis													biological_process											owl:Class	
GO:0047711	biolink:NamedThing	blasticidin-S deaminase activity	Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3.	got7fsn_ti	blasticidin-S aminohydrolase activity											RHEA:10148|EC:3.5.4.23|MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN		molecular_function											owl:Class	
GO:0006799	biolink:NamedThing	polyphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.	got7fsn_ti	polyphosphate biosynthesis|polyphosphate synthesis|polyphosphate formation|polyphosphate anabolism													biological_process											owl:Class	
GO:0034438	biolink:NamedThing	lipoprotein amino acid oxidation	The modification of a lipoprotein by oxidation of one or more amino acids in the protein.	got7fsn_ti														biological_process											owl:Class	
GO:0009164	biolink:NamedThing	nucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	got7fsn_ti	nucleoside breakdown|nucleoside degradation|nucleoside catabolism													biological_process											owl:Class	
GO:1900585	biolink:NamedThing	arugosin metabolic process	The chemical reactions and pathways involving arugosin.	got7fsn_ti	arugosin metabolism						di	2012-05-15T06:48:15Z						biological_process											owl:Class	
GO:1900795	biolink:NamedThing	terrequinone A catabolic process	The chemical reactions and pathways resulting in the breakdown of terrequinone A.	got7fsn_ti	terrequinone A degradation|terrequinone A catabolism|terrequinone A breakdown						di	2012-06-04T09:45:41Z						biological_process											owl:Class	
GO:0071079	biolink:NamedThing	alpha2-beta1 integrin-chondroadherin complex	A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.	got7fsn_ti	ITGA2-ITGB1-CHAD complex						mah	2009-11-06T04:42:55Z						cellular_component											owl:Class	
GO:0010470	biolink:NamedThing	regulation of gastrulation	Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.	got7fsn_ti														biological_process											owl:Class	
GO:0070783	biolink:NamedThing	growth of unicellular organism as a thread of attached cells	A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.	got7fsn_ti							mah	2009-07-07T02:21:14Z						biological_process											owl:Class	
GO:0002003	biolink:NamedThing	angiotensin maturation	The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood.	got7fsn_ti	angiotensin catabolic process in blood										GO:0002005			biological_process											owl:Class	
GO:0010273	biolink:NamedThing	detoxification of copper ion	Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.	got7fsn_ti														biological_process											owl:Class	
GO:0097709	biolink:NamedThing	connective tissue replacement	The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared.	got7fsn_ti							pr	2016-05-17T10:49:10Z						biological_process											owl:Class	
GO:0120301	biolink:NamedThing	histone lactyltransferase activity	Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[histone].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20685					krc	2021-01-19T03:38:56Z						molecular_function											owl:Class	
GO:0120300	biolink:NamedThing	peptide lactyltransferase activity	Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[protein].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20685					krc	2021-01-19T03:35:54Z				RHEA:61996		molecular_function											owl:Class	
GO:0036317	biolink:NamedThing	tyrosyl-RNA phosphodiesterase activity	Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis.	got7fsn_ti	VPg unlinkase activity|unlinkase activity|uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity|Y-pUpN PDE activity						bf	2012-08-30T11:08:04Z						molecular_function											owl:Class	
GO:0070713	biolink:NamedThing	RNA guanosine-cytidine insertion	The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide.	got7fsn_ti	RNA GC insertion						mah	2009-06-08T05:31:43Z						biological_process											owl:Class	
GO:0047094	biolink:NamedThing	3-hydroxyphenylacetate 6-hydroxylase activity	Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate.	got7fsn_ti	3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating)|3-hydroxyphenylacetate 6-monooxygenase activity											MetaCyc:1.14.13.63-RXN|EC:1.14.13.63		molecular_function											owl:Class	
GO:0042975	biolink:NamedThing	peroxisome proliferator activated receptor binding	Binding to a peroxisome proliferator activated receptor, alpha, beta or gamma.	got7fsn_ti	PPAR binding													molecular_function											owl:Class	
GO:0008961	biolink:NamedThing	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity	Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein.	got7fsn_ti												EC:2.5.1.145|RHEA:56712		molecular_function											owl:Class	
GO:1900352	biolink:NamedThing	negative regulation of methanofuran biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process.	got7fsn_ti	negative regulation of methanofuran biosynthesis|down regulation of methanofuran biosynthesis|down regulation of methanofuran biosynthetic process|downregulation of methanofuran biosynthetic process|inhibition of methanofuran biosynthesis|down-regulation of methanofuran biosynthetic process|inhibition of methanofuran biosynthetic process|down-regulation of methanofuran biosynthesis|downregulation of methanofuran biosynthesis						tt	2012-04-06T02:14:00Z						biological_process											owl:Class	
GO:0098808	biolink:NamedThing	mRNA cap binding	Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0047412	biolink:NamedThing	N-(long-chain-acyl)ethanolamine deacylase activity	Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid.	got7fsn_ti	acylethanolamine amidase activity|N-(long-chain-acyl)ethanolamine amidohydrolase activity|N-acylethanolamine amidohydrolase activity											MetaCyc:3.5.1.60-RXN|EC:3.5.1.60|RHEA:17505		molecular_function											owl:Class	
GO:0047887	biolink:NamedThing	farnesyl diphosphate kinase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP.	got7fsn_ti	ATP:farnesyl-diphosphate phosphotransferase activity|farnesyl-diphosphate kinase activity|farnesyl pyrophosphate kinase activity											EC:2.7.4.18|MetaCyc:FARNESYL-DIPHOSPHATE-KINASE-RXN|RHEA:21544|KEGG_REACTION:R02303		molecular_function											owl:Class	
GO:0080101	biolink:NamedThing	phosphatidyl-N-dimethylethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.	got7fsn_ti							dhl	2009-04-23T04:02:41Z				MetaCyc:RXN4FS-2|KEGG_REACTION:R01320|RHEA:32739|EC:2.1.1.71		molecular_function											owl:Class	
GO:0009979	biolink:NamedThing	16:0 monogalactosyldiacylglycerol desaturase activity	Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0061321	biolink:NamedThing	garland nephrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	got7fsn_ti	garland cell differentiation						dph	2010-09-24T12:28:16Z			GO:0007514			biological_process											owl:Class	
GO:0038201	biolink:NamedThing	TOR complex	A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K.	got7fsn_ti	target of rapamycin complex|TOR signaling complex|mTOR complex						bf	2013-12-09T14:38:09Z						cellular_component											owl:Class	
GO:0034458	biolink:NamedThing	3'-5' RNA helicase activity	Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis.	got7fsn_ti	3' to 5' RNA helicase activity|ATP-dependent 3'-5' RNA helicase activity|ATP-dependent 3' to 5' RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612									GO:0034459			molecular_function											owl:Class	
GO:0007352	biolink:NamedThing	zygotic specification of dorsal/ventral axis	The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote.	got7fsn_ti	zygotic determination of dorsal-ventral axis|zygotic determination of dorsal/ventral axis|zygotic determination of dorsoventral axis													biological_process											owl:Class	
GO:0055047	biolink:NamedThing	generative cell mitosis	The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.	got7fsn_ti														biological_process											owl:Class	
GO:1990778	biolink:NamedThing	protein localization to cell periphery	A process in which a protein is transported to, or maintained in, the cell periphery.	got7fsn_ti								2015-06-18T22:37:39Z						biological_process											owl:Class	
GO:0044229	biolink:NamedThing	host cell periplasmic space	The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi).	got7fsn_ti							jl	2009-12-03T01:52:31Z						cellular_component											owl:Class	
GO:0047204	biolink:NamedThing	chlorogenate-glucarate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate.	got7fsn_ti	chlorogenate:glucarate O-(hydroxycinnamoyl)transferase activity|chlorogenic acid:glucaric acid O-caffeoyltransferase activity|chlorogenate:glucarate caffeoyltransferase activity											KEGG_REACTION:R02998|RHEA:23204|EC:2.3.1.98|MetaCyc:2.3.1.98-RXN		molecular_function											owl:Class	
GO:0046922	biolink:NamedThing	peptide-O-fucosyltransferase activity	Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.	got7fsn_ti	GDP-fucose protein O-fucosyltransferase activity|GDP-L-fucose:polypeptide fucosyltransferase activity|GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity|GDP-fucose:polypeptide fucosyltransferase activity											MetaCyc:2.4.1.221-RXN|Reactome:R-HSA-5173192|EC:2.4.1.221|Reactome:R-HSA-1912349		molecular_function											owl:Class	
GO:0003964	biolink:NamedThing	RNA-directed DNA polymerase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.	got7fsn_ti	deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity|RNA-directed DNA polymerase, transposon encoded|RNA-instructed DNA polymerase activity|RNA revertase activity|RNA-directed DNA polymerase, group II intron encoded|DNA nucleotidyltransferase (RNA-directed) activity|RT|reverse transcriptase activity|RNA-dependent deoxyribonucleate nucleotidyltransferase activity|revertase activity|RNA-dependent DNA polymerase activity											MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN|EC:2.7.7.49|Reactome:R-HSA-164520|Reactome:R-HSA-164504		molecular_function											owl:Class	
GO:0031041	biolink:NamedThing	O-glycan processing, core 5	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc.	got7fsn_ti														biological_process											owl:Class	
GO:0046697	biolink:NamedThing	decidualization	The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.	got7fsn_ti	decidual cell reaction											Wikipedia:Decidualization		biological_process											owl:Class	
GO:0097437	biolink:NamedThing	maintenance of dormancy	The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.	got7fsn_ti							pr	2012-12-05T15:00:24Z						biological_process											owl:Class	
GO:0035945	biolink:NamedThing	mitochondrial ncRNA surveillance	The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.	got7fsn_ti	mitochondrial non-coding RNA surveillance|mitochondrial aberrant ncRNA catabolic process|mitochondrial ncRNA quality control						bf	2011-07-28T10:34:59Z						biological_process											owl:Class	
GO:0016784	biolink:NamedThing	3-mercaptopyruvate sulfurtransferase activity	Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.	got7fsn_ti	beta-mercaptopyruvate sulfurtransferase activity|3-mercaptopyruvate sulphurtransferase activity|mercaptopyruvate sulfurtransferase activity|3-mercaptopyruvate:cyanide sulfurtransferase activity											Reactome:R-HSA-9013471|EC:2.8.1.2|Reactome:R-HSA-9013533|RHEA:21740|Reactome:R-HSA-9012721|Reactome:R-HSA-9034756|MetaCyc:MERCAPYSTRANS-RXN		molecular_function											owl:Class	
GO:0033923	biolink:NamedThing	glucan 1,6-alpha-isomaltosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.	got7fsn_ti	isomaltodextranase activity|exo-isomaltohydrolase activity|isomalto-dextranase activity|G2-dextranase activity|1,6-alpha-D-glucan isomaltohydrolase activity											EC:3.2.1.94|MetaCyc:3.2.1.94-RXN		molecular_function											owl:Class	
GO:0060360	biolink:NamedThing	negative regulation of leucine import in response to ammonium ion	Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle.	got7fsn_ti	negative regulation of leucine uptake in response to ammonium ion													biological_process											owl:Class	
GO:0060358	biolink:NamedThing	negative regulation of leucine import	Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.	got7fsn_ti														biological_process											owl:Class	
GO:0102473	biolink:NamedThing	eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity	Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 8C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP(3-) + H+.	got7fsn_ti												MetaCyc:RXN-14079		molecular_function											owl:Class	
GO:0004652	biolink:NamedThing	polynucleotide adenylyltransferase activity	Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.	got7fsn_ti	polyadenylic acid polymerase activity|polyadenylate polymerase activity|ATP:polynucleotide adenylyltransferase activity|poly-A polymerase activity|ATP:polynucleotidylexotransferase activity|polyadenylic polymerase activity|ATP-polynucleotide adenylyltransferase activity|poly(A) hydrolase activity|poly(A) polymerase activity|RNA adenylating enzyme activity|terminal riboadenylate transferase activity|adenosine triphosphate:ribonucleic acid adenylyltransferase activity|poly(A) synthetase activity|polyadenylate synthetase activity|AMP polynucleotidylexotransferase activity|RNA formation factors, PF1|polyadenylate nucleotidyltransferase activity|NTP polymerase activity											MetaCyc:POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.19|RHEA:11332|Reactome:R-HSA-72185		molecular_function											owl:Class	
GO:0047845	biolink:NamedThing	deoxylimonate A-ring-lactonase activity	Catalysis of the reaction: deoxylimonoate + H(2)O = deoxylimononate D-ring-lactone + H(+).	got7fsn_ti	deoxylimonate A-ring-lactonohydrolase activity											EC:3.1.1.46|RHEA:14997|MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN|KEGG_REACTION:R03803		molecular_function											owl:Class	
GO:0080077	biolink:NamedThing	trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule.	got7fsn_ti							dhl	2009-04-14T04:00:45Z						molecular_function											owl:Class	
GO:0050338	biolink:NamedThing	thiosulfate dehydrogenase activity	Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.	got7fsn_ti	thiosulfate oxidase activity|thiosulfate-acceptor oxidoreductase activity|thiosulphate dehydrogenase activity|thiosulfate:ferricytochrome-c oxidoreductase activity|thiosulfate-oxidizing enzyme|tetrathionate synthase activity											RHEA:20549|EC:1.8.2.2|MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0018706	biolink:NamedThing	pyrogallol hydroxytransferase activity	Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.	got7fsn_ti	1,2,3,5-tetrahydroxybenzene hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase)|1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase activity|pyrogallol hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase activity|transhydroxylase activity											EC:1.97.1.2|RHEA:21000|MetaCyc:1.97.1.2-RXN|UM-BBD_reactionID:r0006		molecular_function											owl:Class	
GO:0008460	biolink:NamedThing	dTDP-glucose 4,6-dehydratase activity	Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O.	got7fsn_ti	TDP-glucose oxidoreductase activity|dTDPglucose 4,6-hydro-lyase activity|dTDPglucose 4,6-dehydratase activity|dTDP-glucose 4,6-hydro-lyase activity|dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-D-glucose-forming)|thymidine diphosphoglucose oxidoreductase activity											RHEA:17221|KEGG_REACTION:R06513|EC:4.2.1.46|MetaCyc:DTDPGLUCDEHYDRAT-RXN		molecular_function											owl:Class	
GO:0047852	biolink:NamedThing	diferric-transferrin reductase activity	Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH.	got7fsn_ti	transferrin[Fe(II)]2:NAD+ oxidoreductase activity|transferrin reductase activity|NADH diferric transferrin reductase activity|diferric transferrin reductase activity											RHEA:13841|MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN|EC:1.16.1.2		molecular_function											owl:Class	
GO:0048506	biolink:NamedThing	regulation of timing of meristematic phase transition	Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point.	got7fsn_ti														biological_process											owl:Class	
GO:0061391	biolink:NamedThing	negative regulation of direction of cell growth	Any process that decreases the direction of cell growth.	got7fsn_ti							dph	2011-07-14T10:25:55Z						biological_process											owl:Class	
GO:1900764	biolink:NamedThing	emericellin metabolic process	The chemical reactions and pathways involving emericellin.	got7fsn_ti	Variecoxanthone B metabolic process|emericellin metabolism|Variecoxanthone B metabolism						di	2012-06-04T09:17:58Z						biological_process											owl:Class	
GO:0102413	biolink:NamedThing	6-O-methyl-deacetylisoipecoside beta-glucosidase activity	Catalysis of the reaction: 6-O-methyl-N-deacetylisoipecoside + H2O <=> 6-O-methyl-N-deacetylisoipecoside aglycon + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-13791		molecular_function											owl:Class	
GO:0032342	biolink:NamedThing	aldosterone biosynthetic process	The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.	got7fsn_ti														biological_process											owl:Class	
GO:0021678	biolink:NamedThing	third ventricle development	The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina.	got7fsn_ti														biological_process											owl:Class	
GO:0033650	biolink:NamedThing	host cell mitochondrion	A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	host mitochondria													cellular_component											owl:Class	
GO:0019935	biolink:NamedThing	cyclic-nucleotide-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.	got7fsn_ti	cyclic-nucleotide-mediated signalling													biological_process											owl:Class	
GO:0048927	biolink:NamedThing	posterior lateral line neuromast support cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.	got7fsn_ti														biological_process											owl:Class	
GO:0048889	biolink:NamedThing	neuromast support cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.	got7fsn_ti														biological_process											owl:Class	
GO:0035839	biolink:NamedThing	non-growing cell tip	A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.	got7fsn_ti	new cell end|non-growing cell end						bf	2011-05-06T01:32:21Z						cellular_component											owl:Class	
GO:0043447	biolink:NamedThing	alkane biosynthetic process	The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.	got7fsn_ti	alkane biosynthesis|alkane synthesis|alkane formation|alkane anabolism													biological_process											owl:Class	
GO:0062072	biolink:NamedThing	H3K9me3 modified histone binding	Binding to a histone H3 in which the lysine residue at position 9 has been modified by trimethylation.	got7fsn_ti							dph	2018-09-05T12:58:43Z						molecular_function											owl:Class	
GO:0035064	biolink:NamedThing	methylated histone binding	Binding to a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.	got7fsn_ti														molecular_function											owl:Class	
GO:0003225	biolink:NamedThing	left ventricular trabecular myocardium morphogenesis	The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized.	got7fsn_ti							dph	2009-10-13T10:45:09Z						biological_process											owl:Class	
GO:0043467	biolink:NamedThing	regulation of generation of precursor metabolites and energy	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.	got7fsn_ti														biological_process											owl:Class	
GO:0050395	biolink:NamedThing	vitexin beta-glucosyltransferase activity	Catalysis of the reaction: UDP-D-glucose + vitexin = H(+) + UDP + vitexin 2''-O-beta-D-glucoside.	got7fsn_ti	uridine diphosphoglucose-vitexin 2''-glucosyltransferase activity|vitexin b-glucosyltransferase activity|UDPglucose:vitexin 2''-O-beta-D-glucosyltransferase activity|UDP-glucose:vitexin 2''-O-beta-D-glucosyltransferase activity											MetaCyc:VITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.105|KEGG_REACTION:R03565|RHEA:21956		molecular_function											owl:Class	
GO:0061579	biolink:NamedThing	N-acyl homoserine lactone synthase activity	Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone.	got7fsn_ti	autoinducer-1 synthase						dph	2013-11-15T19:48:23Z				EC:2.3.1.184|RHEA:10096		molecular_function											owl:Class	
GO:0004156	biolink:NamedThing	dihydropteroate synthase activity	Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate.	got7fsn_ti	7,8-dihydropteroate synthetase activity|DHPS activity|7,8-dihydropteroic acid synthetase activity|dihydropteroate pyrophosphorylase activity|2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity|7,8-dihydropteroate synthase activity|dihydropteroate synthetase activity|(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity|dihydropteroate diphosphorylase activity|dihydropteroic synthetase activity											MetaCyc:H2PTEROATESYNTH-RXN|RHEA:19949|EC:2.5.1.15		molecular_function											owl:Class	
GO:0034826	biolink:NamedThing	1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r1170		molecular_function											owl:Class	
GO:0102111	biolink:NamedThing	gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A20 + 2-oxoglutarate + O2 <=> gibberellin A29 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-113		molecular_function											owl:Class	
GO:0042630	biolink:NamedThing	behavioral response to water deprivation	Any process that results in a change in the behavior of an organism as a result of deprivation of water.	got7fsn_ti	behavioral response to thirst|behavioral response to drought|behavioural response to water deprivation													biological_process											owl:Class	
GO:0072320	biolink:NamedThing	volume-sensitive chloride channel activity	Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.	got7fsn_ti	swell-activated chloride channel						mah	2010-10-26T12:53:38Z						molecular_function											owl:Class	
GO:0030038	biolink:NamedThing	contractile actin filament bundle assembly	Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.	got7fsn_ti														biological_process											owl:Class	
GO:0072129	biolink:NamedThing	renal capsule formation	The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.	got7fsn_ti							mah	2010-02-22T02:08:14Z						biological_process											owl:Class	
GO:0000413	biolink:NamedThing	protein peptidyl-prolyl isomerization	The modification of a protein by cis-trans isomerization of a proline residue.	got7fsn_ti	protein proline isomerization													biological_process											owl:Class	
GO:1903349	biolink:NamedThing	omegasome membrane	Any membrane that is part of an omegasome.	got7fsn_ti							pr	2014-08-19T12:33:09Z						cellular_component											owl:Class	
GO:0098588	biolink:NamedThing	bounding membrane of organelle	The lipid bilayer that forms the outer-most layer of an organelle.	got7fsn_ti					Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes.		dos	2014-02-26T13:41:31Z						cellular_component											owl:Class	
GO:0009312	biolink:NamedThing	oligosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	got7fsn_ti	oligosaccharide biosynthesis|oligosaccharide anabolism|oligosaccharide formation|oligosaccharide synthesis													biological_process											owl:Class	
GO:0030750	biolink:NamedThing	putrescine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:putrescine N-methyltransferase activity|putrescine methyltransferase activity											EC:2.1.1.53|RHEA:15037|KEGG_REACTION:R01153|MetaCyc:PUTRESCINE-N-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0080129	biolink:NamedThing	proteasome core complex assembly	The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.	got7fsn_ti	20S proteasome assembly						dhl	2009-04-29T03:34:50Z						biological_process											owl:Class	
GO:0043248	biolink:NamedThing	proteasome assembly	The aggregation, arrangement and bonding together of a mature, active proteasome complex.	got7fsn_ti	26S proteasome assembly|proteasome maturation|proteasome complex assembly													biological_process											owl:Class	
GO:0006174	biolink:NamedThing	dADP phosphorylation	The process of introducing a phosphate group into dADP, deoxyadenosine diphosphate, to produce dATP.	got7fsn_ti														biological_process											owl:Class	
GO:0001893	biolink:NamedThing	maternal placenta development	Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	got7fsn_ti	decidua development													biological_process											owl:Class	
GO:0001866	biolink:NamedThing	NK T cell proliferation	The expansion of a NK T cell population by cell division.	got7fsn_ti	NKT cell proliferation|NT cell proliferation|NK T-lymphocyte proliferation|NK T-cell proliferation|natural T cell proliferation|NK T lymphocyte proliferation|natural killer T cell proliferation				Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments.									biological_process											owl:Class	
GO:0021618	biolink:NamedThing	hypoglossal nerve morphogenesis	The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	got7fsn_ti	CN XII morphogenesis													biological_process											owl:Class	
GO:0021986	biolink:NamedThing	habenula development	The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.	got7fsn_ti														biological_process											owl:Class	
GO:0031892	biolink:NamedThing	type 2 vasoactive intestinal polypeptide receptor binding	Binding to a type 2 vasoactive intestinal polypeptide receptor.	got7fsn_ti	type 2 vasoactive intestinal polypeptide receptor ligand|type 3 PACAP receptor binding													molecular_function											owl:Class	
GO:0031890	biolink:NamedThing	vasoactive intestinal polypeptide receptor binding	Binding to a vasoactive intestinal polypeptide receptor.	got7fsn_ti	vasoactive intestinal polypeptide receptor ligand|VIP receptor binding													molecular_function											owl:Class	
GO:0072248	biolink:NamedThing	metanephric glomerular visceral epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	got7fsn_ti	metanephric podocyte differentiation						mah	2010-03-19T03:44:57Z						biological_process											owl:Class	
GO:0031916	biolink:NamedThing	regulation of synaptic metaplasticity	A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.	got7fsn_ti														biological_process											owl:Class	
GO:0047546	biolink:NamedThing	2-hydroxypyridine 5-monooxygenase activity	Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O(2) = 2,5-dihydroxypyridine + A + H(2)O.	got7fsn_ti	2-hydroxypyridine oxygenase activity|2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating)											MetaCyc:2-HYDROXYPYRIDINE-5-MONOOXYGENASE-RXN|EC:1.14.99.26|KEGG_REACTION:R03206|RHEA:16973		molecular_function											owl:Class	
GO:0050109	biolink:NamedThing	morphine 6-dehydrogenase activity	Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.	got7fsn_ti	morphine:NAD(P)+ 6-oxidoreductase activity|reductase, naloxone|naloxone reductase activity											EC:1.1.1.218|MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0061819	biolink:NamedThing	telomeric DNA-containing double minutes formation	A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.	got7fsn_ti	TDMs formation						dph	2016-12-20T09:49:03Z						biological_process											owl:Class	
GO:0080104	biolink:NamedThing	5-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate.	got7fsn_ti							dhl	2009-04-23T04:28:25Z						molecular_function											owl:Class	
GO:0004631	biolink:NamedThing	phosphomevalonate kinase activity	Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H(+).	got7fsn_ti	ATP:5-phosphomevalonate phosphotransferase activity|mevalonic acid phosphate kinase activity|mevalonate phosphate kinase activity|mevalonate-5-phosphate kinase activity|5-phosphomevalonate kinase activity|ATP:(R)-5-phosphomevalonate phosphotransferase activity											Reactome:R-HSA-191422|KEGG_REACTION:R03245|MetaCyc:PHOSPHOMEVALONATE-KINASE-RXN|RHEA:16341|EC:2.7.4.2		molecular_function											owl:Class	
GO:0102720	biolink:NamedThing	acetyl-coenzyme A:acetyl alcohol acetyltransferase activity	Catalysis of the reaction: benzyl alcohol + acetyl-CoA = benzyl acetate + coenzyme A.	got7fsn_ti												RHEA:36147|MetaCyc:RXN-6762|EC:2.3.1.224		molecular_function											owl:Class	
GO:0004833	biolink:NamedThing	tryptophan 2,3-dioxygenase activity	Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.	got7fsn_ti	indoleamine-pyrrole 2,3-dioxygenase activity|tryptophan peroxidase activity|tryptophan pyrrolase activity|L-tryptophan pyrrolase activity|L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)|TDO|L-tryptophan 2,3-dioxygenase activity|tryptamin 2,3-dioxygenase activity|indolamine 2,3-dioxygenase activity|tryptamine 2,3-dioxygenase activity|tryptophan oxygenase activity										GO:0004426	RHEA:24536|EC:1.13.11.11|Reactome:R-HSA-198563|MetaCyc:TRYPTOPHAN-23-DIOXYGENASE-RXN|Reactome:R-HSA-888614|Reactome:R-HSA-71188		molecular_function											owl:Class	
GO:0021526	biolink:NamedThing	medial motor column neuron differentiation	The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:1900591	biolink:NamedThing	violaceol II metabolic process	The chemical reactions and pathways involving violaceol II.	got7fsn_ti	violaceol II metabolism						di	2012-05-15T06:51:21Z						biological_process											owl:Class	
GO:0070740	biolink:NamedThing	tubulin-glutamic acid ligase activity	Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule.	got7fsn_ti	tubulin glutamylase activity|tubulin-glutamate ligase activity						mah	2009-06-19T02:26:15Z				Reactome:R-HSA-8865774|Reactome:R-HSA-8955869		molecular_function											owl:Class	
GO:0008494	biolink:NamedThing	translation activator activity	Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide.	got7fsn_ti														molecular_function											owl:Class	
GO:0140496	biolink:NamedThing	gamma-tubulin complex binding	Binding to a gamma-tubulin complex.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19788					pg	2020-07-17T08:14:32Z						molecular_function											owl:Class	
GO:0033180	biolink:NamedThing	proton-transporting V-type ATPase, V1 domain	A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.	got7fsn_ti														cellular_component											owl:Class	
GO:0033178	biolink:NamedThing	proton-transporting two-sector ATPase complex, catalytic domain	A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled.	got7fsn_ti														cellular_component											owl:Class	
GO:0070310	biolink:NamedThing	ATR-ATRIP complex	A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A.	got7fsn_ti	Rad3-Rad26 complex|Mec1-Lcd1 complex													cellular_component											owl:Class	
GO:0001173	biolink:NamedThing	DNA-templated transcriptional start site selection	Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	got7fsn_ti	DNA-dependent transcriptional start site selection						krc	2011-06-20T12:44:11Z						biological_process											owl:Class	
GO:0006973	biolink:NamedThing	intracellular accumulation of glycerol	The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment.	got7fsn_ti														biological_process											owl:Class	
GO:0042373	biolink:NamedThing	vitamin K metabolic process	The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.	got7fsn_ti	naphthoquinone metabolic process|vitamin K metabolism|naphthoquinone metabolism													biological_process											owl:Class	
GO:0106244	biolink:NamedThing	eupatolide synthase activity	Catalysis of the reaction: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							hjd	2019-12-20T14:50:15Z				RHEA:57972|EC:1.14.14.169		molecular_function											owl:Class	
GO:0042560	biolink:NamedThing	pteridine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.	got7fsn_ti	pteridine and derivative catabolic process|pteridine-containing compound catabolism|pteridine-containing compound degradation|pterin catabolic process|pterin catabolism|pteridine-containing compound breakdown|pteridine and derivative catabolism													biological_process											owl:Class	
GO:0021963	biolink:NamedThing	spinothalamic tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling.	got7fsn_ti	dorsolateral tract of Lissauer morphogenesis													biological_process											owl:Class	
GO:0061415	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	got7fsn_ti							dph	2012-01-23T11:33:08Z						biological_process											owl:Class	
GO:0016497	biolink:NamedThing	substance K receptor activity	Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity.	got7fsn_ti	neuromedin L receptor activity|neurokinin A receptor activity													molecular_function											owl:Class	
GO:0004995	biolink:NamedThing	tachykinin receptor activity	Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0070187	biolink:NamedThing	shelterin complex	A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1.	got7fsn_ti	Pot1-Tpz1 complex|Pot1 complex|telosome													cellular_component											owl:Class	
GO:0009676	biolink:NamedThing	low-affinity sulfate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low affinity sulfate:hydrogen symporter activity|low affinity sulfate:proton symporter activity|low affinity sulphate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0008512	biolink:NamedThing	sulfate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in).	got7fsn_ti	sulfate:hydrogen symporter activity|sulfate/hydrogen symporter activity|sulphate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0018392	biolink:NamedThing	glycoprotein 3-alpha-L-fucosyltransferase activity	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+).	got7fsn_ti	GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-1,3-fucosyltransferase activity|GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1->6-GlcNAc)-Asn-peptide) alpha-1->3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity|GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6-GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity|GDP-L-fucose:asparagine-linked N-acetylglucosamine alpha(1,3)-fucosyltransferase activity|GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase activity|GDP-L-Fuc:Asn-linked GlcNAc alpha-1,3-fucosyltransferase activity											RHEA:24444|EC:2.4.1.214|KEGG_REACTION:R06015|MetaCyc:2.4.1.214-RXN		molecular_function											owl:Class	
GO:0046920	biolink:NamedThing	alpha-(1->3)-fucosyltransferase activity	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage.	got7fsn_ti	alpha-(1,3)-fucosyltransferase activity|alpha(1,3)-fucosyltransferase activity|alpha-1,3-fucosyltransferase activity											Reactome:R-HSA-9605644|Reactome:R-HSA-9605682|Reactome:R-HSA-9603984|Reactome:R-HSA-9605609		molecular_function											owl:Class	
GO:0018839	biolink:NamedThing	cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity	Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.	got7fsn_ti												EC:5.2.1.-|UM-BBD_reactionID:r0163		molecular_function											owl:Class	
GO:0047723	biolink:NamedThing	inosinate nucleosidase activity	Catalysis of the reaction: H(2)O + IMP = D-ribose 5-phosphate + hypoxanthine.	got7fsn_ti	5'-inosinate phosphoribohydrolase activity											RHEA:20469|EC:3.2.2.12|KEGG_REACTION:R01128|MetaCyc:INOSINATE-NUCLEOSIDASE-RXN		molecular_function											owl:Class	
GO:0072331	biolink:NamedThing	signal transduction by p53 class mediator	An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.	got7fsn_ti							mah	2010-11-03T01:32:59Z						biological_process											owl:Class	
GO:2000542	biolink:NamedThing	negative regulation of gastrulation	Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation.	got7fsn_ti							yaf	2011-04-01T04:10:08Z						biological_process											owl:Class	
GO:0050067	biolink:NamedThing	lysine 2-monooxygenase activity	Catalysis of the reaction: L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O.	got7fsn_ti	lysine oxygenase activity|lysine monooxygenase activity|L-lysine:oxygen 2-oxidoreductase (decarboxylating)|L-lysine-2-monooxygenase activity											RHEA:14601|EC:1.13.12.2|MetaCyc:LYSINE-2-MONOOXYGENASE-RXN|KEGG_REACTION:R00449		molecular_function											owl:Class	
GO:0030123	biolink:NamedThing	AP-3 adaptor complex	A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).	got7fsn_ti														cellular_component											owl:Class	
GO:0007306	biolink:NamedThing	eggshell chorion assembly	Construction of the chorion portion of the eggshell, which comprises the channels for gas exchange in an insect eggshell.	got7fsn_ti	insect chorion formation|eggshell chorion formation													biological_process											owl:Class	
GO:0102109	biolink:NamedThing	tricaffeoyl spermidine O-methyltransferase activity	Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine  <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-11261		molecular_function											owl:Class	
GO:0010426	biolink:NamedThing	DNA methylation on cytosine within a CHH sequence	The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide.	got7fsn_ti	cytosine methylation within a CHH sequence|cytosine methylation within a CNN sequence|DNA methylation on cytosine within a CNN sequence													biological_process											owl:Class	
GO:0017196	biolink:NamedThing	N-terminal peptidyl-methionine acetylation	The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.	got7fsn_ti												RESID:AA0049		biological_process											owl:Class	
GO:0043875	biolink:NamedThing	2-ketobutyrate formate-lyase activity	Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate.	got7fsn_ti	KFL|TdcE|keto-acid formate acetyltransferase				This function is part of an anaerobic pathway for the catabolism of L-threonine.							MetaCyc:KETOBUTFORMLY-RXN		molecular_function											owl:Class	
GO:0061815	biolink:NamedThing	deubiquitinase, acting on linear ubiquitin	Catalysis of the hydrolysis of ubiquitin units from linear ubiquitin chains.	got7fsn_ti	linear ubiquitin specific deubiquitinase activity|ubiquitinyl hydrolase activity, acting on linear ubiquitin|Met1 linkage specific DUB						dph	2016-11-28T13:58:44Z						molecular_function											owl:Class	
GO:0016495	biolink:NamedThing	C-X3-C chemokine receptor activity	Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.	got7fsn_ti														molecular_function											owl:Class	
GO:1990623	biolink:NamedThing	Herring body	The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release. Each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively.	got7fsn_ti	neurosecretory body						cls	2015-01-29T21:11:54Z						cellular_component											owl:Class	
GO:0007323	biolink:NamedThing	peptide pheromone maturation	The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	pheromone processing										GO:0046613|GO:0007326|GO:0007324			biological_process											owl:Class	
GO:0102208	biolink:NamedThing	2-polyprenyl-6-hydroxyphenol methylase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine  + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.	got7fsn_ti												MetaCyc:RXN-12160|RHEA:31411		molecular_function											owl:Class	
GO:0008744	biolink:NamedThing	L-xylulokinase activity	Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate.	got7fsn_ti	L-xylulokinase (phosphorylating)|ATP:L-xylulose 5-phosphotransferase activity|L-xylulose kinase activity											EC:2.7.1.53|MetaCyc:LYXK-RXN|RHEA:18869		molecular_function											owl:Class	
GO:0004856	biolink:NamedThing	xylulokinase activity	Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H(+).	got7fsn_ti	xylulokinase (phosphorylating)|xylulose kinase activity|D-xylulokinase activity|ATP:D-xylulose 5-phosphotransferase activity											RHEA:10964|KEGG_REACTION:R01639|EC:2.7.1.17|Reactome:R-HSA-5662466|MetaCyc:XYLULOKIN-RXN		molecular_function											owl:Class	
GO:0052022	biolink:NamedThing	modulation by symbiont of jasmonic acid levels in host	The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of jasmonic acid levels in other organism involved in symbiotic interaction										GO:0052456			biological_process											owl:Class	
GO:0001766	biolink:NamedThing	membrane raft polarization	The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.	got7fsn_ti	membrane polarization|lipid raft polarization	https://github.com/geneontology/go-ontology/issues/20666												biological_process											owl:Class	
GO:0071015	biolink:NamedThing	U12-type prespliceosome	A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.	got7fsn_ti	mammalian U12-type spliceosomal complex A|yeast U12-type spliceosomal complex B|minor prespliceosome|AT-AC prespliceosome						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0071010	biolink:NamedThing	prespliceosome	A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.	got7fsn_ti	mammalian spliceosomal complex A|prespliceosomal complex|yeast spliceosomal complex B						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0019216	biolink:NamedThing	regulation of lipid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.	got7fsn_ti	regulation of lipid metabolism													biological_process											owl:Class	
GO:0031918	biolink:NamedThing	positive regulation of synaptic metaplasticity	A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.	got7fsn_ti	activation of synaptic metaplasticity|up-regulation of synaptic metaplasticity|upregulation of synaptic metaplasticity|stimulation of synaptic metaplasticity|up regulation of synaptic metaplasticity													biological_process											owl:Class	
GO:0031915	biolink:NamedThing	positive regulation of synaptic plasticity	A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	got7fsn_ti	activation of synaptic plasticity|stimulation of synaptic plasticity|up-regulation of synaptic plasticity|upregulation of synaptic plasticity|up regulation of synaptic plasticity													biological_process											owl:Class	
GO:1990350	biolink:NamedThing	glucose transporter complex	A protein complex facilitating glucose transport into, out of or within a cell, or between cells.	got7fsn_ti					An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).		bhm	2014-03-26T14:12:05Z						cellular_component											owl:Class	
GO:0050213	biolink:NamedThing	progesterone 5-alpha-reductase activity	Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH.	got7fsn_ti	delta4-steroid 5alpha-reductase (progesterone)|progesterone 5alpha-reductase activity|progesterone 5a-reductase activity|5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase activity|steroid 5-alpha-reductase activity											EC:1.3.1.30|RHEA:21952|MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0045895	biolink:NamedThing	positive regulation of mating-type specific transcription, DNA-templated	Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription.	got7fsn_ti	activation of transcription, mating-type specific|up-regulation of transcription, mating-type specific|upregulation of transcription, mating-type specific|stimulation of transcription, mating-type specific|positive regulation of mating-type specific transcription, DNA-dependent|up regulation of transcription, mating-type specific													biological_process											owl:Class	
GO:0043472	biolink:NamedThing	IgD binding	Binding to an immunoglobulin of a D isotype.	got7fsn_ti														molecular_function											owl:Class	
GO:0052098	biolink:NamedThing	formation by host of specialized structure for nutrient acquisition from symbiont	The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0052095	biolink:NamedThing	formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction	The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	formation of specialized structure for nutrient acquisition from other organism during symbiotic interaction													biological_process											owl:Class	
GO:0019704	biolink:NamedThing	peptidyl-L-cysteine S-myristoylation	The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine.	got7fsn_ti	peptidyl-S-myristoyl-L-cysteine biosynthetic process from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine synthesis from peptidyl-cysteine											RESID:AA0307		biological_process											owl:Class	
GO:0018377	biolink:NamedThing	protein myristoylation	The covalent attachment of a myristoyl group to a protein.	got7fsn_ti	protein amino acid myristoylation										GO:0018319			biological_process											owl:Class	
GO:0031143	biolink:NamedThing	pseudopodium	A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.	got7fsn_ti	reticulopodium|pseudopodial protrusion|axopodium|lobopodium|pseudopod	https://github.com/geneontology/go-ontology/issues/21139|https://github.com/geneontology/go-ontology/issues/21141										Wikipedia:Pseudopod		cellular_component											owl:Class	
GO:0060866	biolink:NamedThing	leaf abscission	The controlled shedding of a leaf.	got7fsn_ti							dph	2009-08-12T06:33:55Z						biological_process											owl:Class	
GO:0016509	biolink:NamedThing	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity|long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity|beta-hydroxyacyl-CoA dehydrogenase activity|LCHAD				Also see '3-hydroxyacyl-CoA dehydrogenase activity ; GO:0003857'.							Reactome:R-HSA-548818|MetaCyc:1.1.1.211-RXN|EC:1.1.1.211		molecular_function											owl:Class	
GO:0003857	biolink:NamedThing	3-hydroxyacyl-CoA dehydrogenase activity	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+).	got7fsn_ti	L-3-hydroxyacyl CoA dehydrogenase activity|beta-hydroxyacyl dehydrogenase activity|beta-hydroxyacylcoenzyme A dehydrogenase activity|beta-keto-reductase activity|beta-hydroxybutyrylcoenzyme A dehydrogenase activity|3-oxoacyl-thioester reductase activity|L-3-hydroxyacyl coenzyme A dehydrogenase activity|beta-ketoacyl-CoA reductase|beta-hydroxyacyl-coenzyme A synthetase activity				See also 'long-chain-3-hydroxyacyl-CoA dehydrogenase activity ; GO:0016509'.							Reactome:R-HSA-193508|Reactome:R-HSA-193455|Reactome:R-HSA-6809264|Reactome:R-HSA-70837|Reactome:R-HSA-508369|Reactome:R-HSA-77323|EC:1.1.1.35|Reactome:R-HSA-390251|Reactome:R-HSA-389995|Reactome:R-HSA-77331|UM-BBD_enzymeID:e0664|Reactome:R-HSA-77312|Reactome:R-HSA-77303|Reactome:R-HSA-77254|Reactome:R-HSA-77342|RHEA:22432|Reactome:R-HSA-77283|MetaCyc:OHACYL-COA-DEHYDROG-RXN		molecular_function											owl:Class	
GO:0097202	biolink:NamedThing	activation of cysteine-type endopeptidase activity	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.	got7fsn_ti	activation of metacaspase activity|activation of caspase activity				This term should be used to annotate gene products within the context of cellular processes other than apoptotic cell death (e.g., cell cycle arrest). To annotate gene products involved in activation of cysteine-type endopeptidases where the activation results in apoptotic process, please use the more granular term GO:0006919.		pr	2011-12-19T02:44:04Z						biological_process											owl:Class	
GO:2001056	biolink:NamedThing	positive regulation of cysteine-type endopeptidase activity	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity.	got7fsn_ti	positive regulation of thiol endopeptidase activity|positive regulation of lysosomal cysteine-type endopeptidase						pr	2011-09-09T08:53:43Z						biological_process											owl:Class	
GO:0002322	biolink:NamedThing	B cell proliferation involved in immune response	The expansion of a B cell population by cell division following B cell activation during an immune response.	got7fsn_ti	B-lymphocyte proliferation during immune response|B lymphocyte proliferation during immune response|B cell proliferation during immune response|B-cell proliferation during immune response													biological_process											owl:Class	
GO:0004838	biolink:NamedThing	L-tyrosine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.	got7fsn_ti	tyrosine-2-ketoglutarate aminotransferase activity|phenylpyruvic acid transaminase activity|L-phenylalanine 2-oxoglutarate aminotransferase activity|tyrosine-alpha-ketoglutarate transaminase activity|phenylalanine transaminase activity|L-tyrosine aminotransferase activity|tyrosine-alpha-ketoglutarate aminotransferase activity|phenylalanine aminotransferase activity|TyrAT activity|glutamic phenylpyruvic aminotransferase activity|tyrosine aminotransferase activity|tyrosine transaminase activity|phenylalanine-alpha-ketoglutarate transaminase activity|phenylpyruvate transaminase activity|glutamic-hydroxyphenylpyruvic transaminase activity											EC:2.6.1.5|Reactome:R-HSA-517444|Reactome:R-HSA-71155|RHEA:15093|MetaCyc:TYROSINE-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0070547	biolink:NamedThing	L-tyrosine aminotransferase activity	Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid.	got7fsn_ti														molecular_function											owl:Class	
GO:1990786	biolink:NamedThing	cellular response to dsDNA	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.	got7fsn_ti							sl	2015-06-24T22:48:25Z						biological_process											owl:Class	
GO:0010690	biolink:NamedThing	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.	got7fsn_ti														biological_process											owl:Class	
GO:0060567	biolink:NamedThing	negative regulation of DNA-templated transcription, termination	Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.	got7fsn_ti	negative regulation of termination of DNA-dependent transcription|negative regulation of DNA-dependent transcription, termination|negative regulation of transcription termination, DNA-dependent						dph	2009-04-29T02:59:12Z						biological_process											owl:Class	
GO:0090488	biolink:NamedThing	polo box domain specific binding	Binding to a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases.	got7fsn_ti							tb	2012-10-16T10:47:30Z						molecular_function											owl:Class	
GO:0008890	biolink:NamedThing	glycine C-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+).	got7fsn_ti	2-amino-3-ketobutyrate-CoA ligase activity|acetyl-CoA:glycine C-acetyltransferase activity|2-amino-3-ketobutyrate CoA ligase activity|glycine acetyltransferase activity|aminoacetone synthase activity|2-amino-3-ketobutyrate coenzyme A ligase activity											RHEA:20736|EC:2.3.1.29|KEGG_REACTION:R00371|MetaCyc:AKBLIG-RXN		molecular_function											owl:Class	
GO:0001050	biolink:NamedThing	single-subunit type RNA polymerase binding	Binding to a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.	got7fsn_ti	T7-type RNA polymerase binding|T3/T7 type RNA polymerase binding|T3-type RNA polymerase binding|SP6-type RNA polymerase binding						krc	2010-09-23T02:33:45Z						molecular_function											owl:Class	
GO:0036380	biolink:NamedThing	UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol.	got7fsn_ti	UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-glucosaminephosphotransferase activity|UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase activity|GlcNAc-P-P-Und synthase activity|UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity						bf	2013-05-23T10:51:26Z				EC:2.7.8.33|KEGG_REACTION:R08856|RHEA:28090|MetaCyc:GLCNACPTRANS-RXN		molecular_function											owl:Class	
GO:0008177	biolink:NamedThing	succinate dehydrogenase (ubiquinone) activity	Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.	got7fsn_ti	succinic dehydrogenase activity|fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)|respiratory complex II|quinol:fumarate oxidoreductase activity|menaquinol: fumarate oxidoreductase activity|succinate:ubiquinone oxidoreductase activity|succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)										GO:0019737	Reactome:R-HSA-163213|MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN|RHEA:13713|KEGG_REACTION:R02164|Reactome:R-HSA-70994|EC:1.3.5.1		molecular_function											owl:Class	
GO:0032256	biolink:NamedThing	establishment of dense core granule localization	The directed movement of a dense core granule to a specific location.	got7fsn_ti	establishment of dense core vesicle localization|establishment of dense core granule localisation													biological_process											owl:Class	
GO:0004790	biolink:NamedThing	thioether S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium.	got7fsn_ti	S-adenosyl-L-methionine:thioether S-methyltransferase activity|S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase activity|thioether methyltransferase activity											MetaCyc:THIOETHER-S-METHYLTRANSFERASE-RXN|KEGG_REACTION:R02572|EC:2.1.1.96|RHEA:19613		molecular_function											owl:Class	
GO:0044373	biolink:NamedThing	cytokinin binding	Binding to a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators.	got7fsn_ti							jl	2011-12-01T03:42:10Z						molecular_function											owl:Class	
GO:0034561	biolink:NamedThing	1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity	Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O.	got7fsn_ti												UM-BBD_reactionID:r0862		molecular_function											owl:Class	
GO:0110056	biolink:NamedThing	positive regulation of actin filament annealing	Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.	got7fsn_ti							kmv	2017-09-20T20:13:09Z						biological_process											owl:Class	
GO:0052753	biolink:NamedThing	propan-2-ol:coenzyme F420 oxidoreductase activity	Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420.	got7fsn_ti	F420-dependent secondary alcohol dehydrogenase activity|F420-dependent propan-2-ol dehydrogenase activity|isopropanol:coenzyme F420 oxidoreductase activity							2011-09-21T05:15:28Z						molecular_function											owl:Class	
GO:0034920	biolink:NamedThing	pyrene dioxygenase activity	Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene.	got7fsn_ti												UM-BBD_reactionID:r0934|EC:1.13.11.-		molecular_function											owl:Class	
GO:0102766	biolink:NamedThing	naringenin 7-O-methyltransferase activity	Catalysis of the reaction: (S)-naringenin(1-) + S-adenosyl-L-methionine  <=> sakuranetin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												RHEA:31539|MetaCyc:RXN-7773|EC:2.1.1.232		molecular_function											owl:Class	
GO:0046379	biolink:NamedThing	extracellular polysaccharide metabolic process	The chemical reactions and pathways involving polysaccharides used in extracellular structures.	got7fsn_ti	extracellular polysaccharide metabolism													biological_process											owl:Class	
GO:1990217	biolink:NamedThing	suppression by symbiont of host phytoalexin production	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host phytoalexin production						ml	2013-10-10T15:49:33Z						biological_process											owl:Class	
GO:0018688	biolink:NamedThing	DDT 2,3-dioxygenase activity	Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.	got7fsn_ti												UM-BBD_reactionID:r0450		molecular_function											owl:Class	
GO:0071889	biolink:NamedThing	14-3-3 protein binding	Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.	got7fsn_ti							mah	2010-09-14T01:21:50Z						molecular_function											owl:Class	
GO:0060742	biolink:NamedThing	epithelial cell differentiation involved in prostate gland development	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.	got7fsn_ti							dph	2009-06-16T09:32:34Z						biological_process											owl:Class	
GO:0008055	biolink:NamedThing	ocellus pigment biosynthetic process	The chemical reactions and pathways resulting in the formation of ocellus pigments,  general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.	got7fsn_ti	ocellus pigment biosynthesis|ocellus pigment anabolism|ocellus pigment formation|ocellus pigment synthesis													biological_process											owl:Class	
GO:0044294	biolink:NamedThing	dendritic growth cone	The migrating motile tip of a growing nerve cell dendrite.	got7fsn_ti	dendrite growth cone						jl	2010-02-04T03:45:27Z				NIF_Subcellular:sao1594955670		cellular_component											owl:Class	
GO:0031875	biolink:NamedThing	type 4 proteinase activated receptor binding	Binding to a type 4 proteinase activated receptor.	got7fsn_ti	type 4 proteinase activated receptor ligand													molecular_function											owl:Class	
GO:1990631	biolink:NamedThing	ErbB-4 class receptor binding	Binding to the protein-tyrosine kinase receptor ErbB-4/HER4.	got7fsn_ti	HER4 receptor binding						sl	2015-02-06T23:28:49Z						molecular_function											owl:Class	
GO:0080166	biolink:NamedThing	stomium development	The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released.	got7fsn_ti							dhl	2010-09-23T05:03:40Z						biological_process											owl:Class	
SO:0000833	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042729	biolink:NamedThing	DASH complex	A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the outer kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.	got7fsn_ti	Duo1p-Dam1p-Dad1p complex|Dam1 complex|condensed nuclear chromosome kinetochore-associated DASH complex|DDD complex	https://github.com/geneontology/go-ontology/issues/21126			Note that this complex is conserved in fungi but has not been observed in metazoans.						GO:0043926|GO:0043925			cellular_component											owl:Class	
GO:0071945	biolink:NamedThing	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.	got7fsn_ti	regulation of bacterial-type flagellum cell motility by regulation of motor speed|regulation of bacterial-type flagellar cell motility by regulation of motor speed|regulation of flagellar cell motility by regulation of motor speed						mah	2010-10-05T04:10:27Z						biological_process											owl:Class	
GO:1902021	biolink:NamedThing	regulation of bacterial-type flagellum-dependent cell motility	Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.	got7fsn_ti	regulation of bacterial-type flagellum cell motility|regulation of flagellin-based flagellar cell motility|regulation of bacterial-type flagellar cell motility						jl	2013-03-27T14:42:50Z						biological_process											owl:Class	
GO:0035844	biolink:NamedThing	cloaca development	The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.	got7fsn_ti	cloacal development						bf	2011-05-06T01:54:35Z						biological_process											owl:Class	
GO:0047283	biolink:NamedThing	dolichyl-phosphate D-xylosyltransferase activity	Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP.	got7fsn_ti	UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase activity											RHEA:15361|EC:2.4.2.32|MetaCyc:2.4.2.32-RXN		molecular_function											owl:Class	
GO:0035252	biolink:NamedThing	UDP-xylosyltransferase activity	Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule.	got7fsn_ti												Reactome:R-HSA-9638090|Reactome:R-HSA-5617138|Reactome:R-HSA-6785668		molecular_function											owl:Class	
GO:0003358	biolink:NamedThing	noradrenergic neuron development	The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti	norepinephrine secreting neuron development						dph	2009-12-03T10:38:37Z						biological_process											owl:Class	
GO:0061262	biolink:NamedThing	mesonephric renal vesicle formation	The developmental process pertaining to the initial formation of the mesonephros.	got7fsn_ti	mesonephros formation						dph	2010-08-30T02:41:20Z						biological_process											owl:Class	
GO:0005139	biolink:NamedThing	interleukin-7 receptor binding	Binding to an interleukin-7 receptor.	got7fsn_ti	IL-7|interleukin-7 receptor ligand													molecular_function											owl:Class	
GO:0042426	biolink:NamedThing	choline catabolic process	The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	got7fsn_ti	choline breakdown|choline degradation|choline catabolism													biological_process											owl:Class	
GO:0033877	biolink:NamedThing	succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity	Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.	got7fsn_ti	succinyl-CoA:benzylsuccinate CoA-transferase activity|benzylsuccinate CoA-transferase activity|succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase activity										GO:0018728	UM-BBD_reactionID:r0329|MetaCyc:RXN-864|KEGG_REACTION:R05588|RHEA:16469|EC:2.8.3.15		molecular_function											owl:Class	
GO:0140473	biolink:NamedThing	telomere-nuclear envelope anchor activity	The binding activity of a molecule that brings together the telomeric region of a chromosome and the inner nuclear membrane by interacting with both the telomere and the nuclear membrane, in order to establish and maintain the telomeric location.	got7fsn_ti	telomere-nuclear envelope anchoring activity|nuclear envelope-telomere anchor activity	https://github.com/geneontology/go-ontology/issues/19229					pg	2020-06-19T15:44:44Z						molecular_function											owl:Class	
GO:0050098	biolink:NamedThing	methylguanidinase activity	Catalysis of the reaction: H(2)O + methylguanidine = methylammonium + urea.	got7fsn_ti	methylguanidine hydrolase activity|methylguanidine amidinohydrolase activity											MetaCyc:METHYLGUANIDINASE-RXN|KEGG_REACTION:R01589|EC:3.5.3.16|RHEA:11764		molecular_function											owl:Class	
GO:0102870	biolink:NamedThing	7-hydroxyflavone-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 7-hydroxyflavone <=> 7-O-beta-D-glucosyl-7-hydroxyflavone + UDP + H+.	got7fsn_ti												MetaCyc:RXN-8355		molecular_function											owl:Class	
GO:0051085	biolink:NamedThing	chaperone cofactor-dependent protein refolding	The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.	got7fsn_ti	chaperone cofactor-dependent 'de novo' protein folding|chaperone co-factor-dependent protein refolding|chaperone co-factor-dependent protein folding|chaperone cofactor-dependent protein folding|chaperone mediated protein folding requiring cofactor	https://github.com/geneontology/go-ontology/issues/10726									GO:0070389			biological_process											owl:Class	
GO:0051084	biolink:NamedThing	'de novo' posttranslational protein folding	The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.	got7fsn_ti	'de novo' post-translational protein folding													biological_process											owl:Class	
GO:0038135	biolink:NamedThing	ERBB2-ERBB4 signaling pathway	A series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.	got7fsn_ti	HER2-HER4 signaling pathway|ERBB2-ERBB4 signalling pathway						bf	2012-03-30T11:19:52Z						biological_process											owl:Class	
GO:0140453	biolink:NamedThing	protein aggregate center	Reversible aggregate of misfolded proteins and chaperones formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.	got7fsn_ti	protein aggregate centre|PAC	https://github.com/geneontology/go-ontology/issues/19172					pg	2020-04-20T15:21:55Z						cellular_component											owl:Class	
GO:0097009	biolink:NamedThing	energy homeostasis	Any process involved in the balance between food intake (energy input) and energy expenditure.	got7fsn_ti	negative regulation of energy homeostasis|regulation of energy homeostasis|positive regulation of energy homeostasis						pr	2011-03-21T10:52:44Z			GO:2000506|GO:2000507|GO:2000505			biological_process											owl:Class	
GO:0038059	biolink:NamedThing	IKKalpha-IKKalpha complex	A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits.	got7fsn_ti	IKKalpha homodimer|IKKalpha homodimeric complex|IkappaB kinase-alpha homodimer|IkappaB kinase alpha homodimer|IKKalpha-IKKalpha protein complex						bf	2012-01-10T09:29:53Z						cellular_component											owl:Class	
GO:0072534	biolink:NamedThing	perineuronal net	A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain.	got7fsn_ti	PNN						mah	2011-01-14T01:37:40Z						cellular_component											owl:Class	
GO:0106143	biolink:NamedThing	tRNA (m7G46) methyltransferase complex	A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat).	got7fsn_ti	tRNA (m7G46) methyltransferase|tRNA m7G methylation complex|Trm8-Trm82 complex						hjd	2018-09-07T14:53:29Z						cellular_component											owl:Class	
GO:0002106	biolink:NamedThing	endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0033512	biolink:NamedThing	L-lysine catabolic process to acetyl-CoA via saccharopine	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.	got7fsn_ti	L-lysine degradation to acetyl-CoA via saccharopine|L-lysine breakdown to acetyl-CoA via saccharopine											MetaCyc:LYSINE-DEG1-PWY		biological_process											owl:Class	
GO:0090057	biolink:NamedThing	root radial pattern formation	The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis.	got7fsn_ti							tb	2009-08-11T02:58:06Z						biological_process											owl:Class	
GO:0009956	biolink:NamedThing	radial pattern formation	The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.	got7fsn_ti	radial pattern specification													biological_process											owl:Class	
GO:0060108	biolink:NamedThing	annular furrow extracellular matrix	The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline.	got7fsn_ti														cellular_component											owl:Class	
GO:0106095	biolink:NamedThing	m7G(5')pppN diphosphatase complex	A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide.	got7fsn_ti	7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase enzyme|M(7)G(5')pppN pyrophosphatase enzyme|m7G(5')pppN pyrophosphatase enzyme|m7G(5')pppN diphosphatase enzyme|DCS1 decapping scavenger complex						hjd	2018-02-07T17:52:03Z						cellular_component											owl:Class	
GO:1903293	biolink:NamedThing	phosphatase complex	A protein complex which is capable of phosphatase activity.	got7fsn_ti					An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay).		bhm	2014-08-13T10:25:32Z						cellular_component											owl:Class	
GO:0003069	biolink:NamedThing	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure	The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure.	got7fsn_ti	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0009763	biolink:NamedThing	NAD-malic enzyme C4 photosynthesis	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme.	got7fsn_ti														biological_process											owl:Class	
GO:0007329	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by pheromones	Any process involving pheromones that activates or increases the rate of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of transcription from Pol II promoter by pheromones|up-regulation of transcription from RNA polymerase II promoter by pheromones|upregulation of transcription from RNA polymerase II promoter by pheromones|activation of transcription from RNA polymerase II promoter by pheromones|up regulation of transcription from RNA polymerase II promoter by pheromones|stimulation of transcription from RNA polymerase II promoter by pheromones													biological_process											owl:Class	
GO:0038136	biolink:NamedThing	ERBB3-ERBB4 signaling pathway	A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors ERBB3 and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	HER3-HER4 signaling pathway|ERBB3-ERBB4 signalling pathway						bf	2012-03-30T11:21:19Z						biological_process											owl:Class	
GO:0090497	biolink:NamedThing	mesenchymal cell migration	The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism.	got7fsn_ti							tb	2012-10-17T12:08:17Z						biological_process											owl:Class	
GO:0047215	biolink:NamedThing	indole-3-acetate beta-glucosyltransferase activity	Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP.	got7fsn_ti	UDPglucose:indole-3-acetate beta-D-glucosyltransferase activity|indol-3-ylacetylglucose synthase activity|IAGlu synthase activity|UDP-glucose:(indol-3-yl)acetate beta-D-glucosyltransferase activity|UDPG-indol-3-ylacetyl glucosyl transferase activity|uridine diphosphoglucose-indoleacetate glucosyltransferase activity|IAA-glucose synthase activity|UDP-glucose:indol-3-ylacetate glucosyltransferase activity|IAA-Glu synthetase activity|UDP-glucose:indol-3-ylacetate glucosyl-transferase activity|UDP-glucose:indol-3-acetic acid glucosyltransferase activity|UDP-glucose:auxin glucosyltransferase activity											RHEA:14921|EC:2.4.1.121|MetaCyc:2.4.1.121-RXN|KEGG_REACTION:R03094		molecular_function											owl:Class	
GO:1990243	biolink:NamedThing	atf1-pcr1 complex	A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).	got7fsn_ti							al	2013-11-28T11:40:28Z						cellular_component											owl:Class	
GO:0035976	biolink:NamedThing	transcription factor AP-1 complex	A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.	got7fsn_ti	Activating protein 1 complex|AP-1 complex|AP1 complex|transcription factor AP1 complex						bf	2011-08-17T10:57:51Z						cellular_component											owl:Class	
GO:0051312	biolink:NamedThing	chromosome decondensation	The alteration of chromosome structure from the condensed form to a relaxed disperse form.	got7fsn_ti														biological_process											owl:Class	
GO:0048171	biolink:NamedThing	negative regulation of long-term neuronal synaptic plasticity	A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.	got7fsn_ti	down regulation of long-term neuronal synaptic plasticity|inhibition of long-term neuronal synaptic plasticity|downregulation of long-term neuronal synaptic plasticity|down-regulation of long-term neuronal synaptic plasticity				Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:0051762	biolink:NamedThing	sesquiterpene biosynthetic process	The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.	got7fsn_ti														biological_process											owl:Class	
GO:0140363	biolink:NamedThing	TIS granule	A ribonucleoprotein granule located in the cytoplasm that is formed by the RNA-binding protein TIS11B and RNA molecules, enriched in membrane protein-encoding mRNAs with multiple AU-rich elements. TIS granules are reticular meshworks intertwined with the endoplasmic reticulum (ER).	got7fsn_ti							pg	2019-07-25T19:20:58Z						cellular_component											owl:Class	
GO:0102989	biolink:NamedThing	5-pentadecatrienylresorcinol synthase activity	Catalysis of the reaction: 3 H+ + 9,12,15-cis-hexadecatrienoyl-CoA + 3 malonyl-CoA(5-) <=> 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + 4 coenzyme A + 4 carbon dioxide.	got7fsn_ti												MetaCyc:RXN-9618		molecular_function											owl:Class	
GO:0008988	biolink:NamedThing	rRNA (adenine-N6-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine.	got7fsn_ti	S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase activity|ErmC 23S rRNA methyltransferase|gene ksgA methyltransferase|ribonucleic acid-adenine (N6) methylase activity|S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase activity|ribosomal ribonucleate adenine 6-methyltransferase activity|ribonucleic acid-adenine (N(6)) methylase activity													molecular_function											owl:Class	
GO:0071924	biolink:NamedThing	chemokine (C-C motif) ligand 22 production	The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	C-C motif chemokine 22 production|CCL22 production|CCL-22 production						mah	2010-09-28T11:33:13Z						biological_process											owl:Class	
GO:0050692	biolink:NamedThing	DNA binding domain binding	Binding to a protein's DNA binding domain (DBD).	got7fsn_ti	DBD binding													molecular_function											owl:Class	
GO:0036379	biolink:NamedThing	myofilament	Any of the smallest contractile units of a myofibril (striated muscle fiber).	got7fsn_ti	striated muscle filament						bf	2013-05-22T14:39:06Z						cellular_component											owl:Class	
GO:0048670	biolink:NamedThing	regulation of collateral sprouting	Any process that modulates the frequency, rate or extent of collateral sprouting.	got7fsn_ti														biological_process											owl:Class	
GO:0046761	biolink:NamedThing	viral budding from plasma membrane	A viral budding that starts with formation of a membrane curvature in the host plasma membrane.	got7fsn_ti	virus budding from plasma membrane by viral capsid envelopment|virus budding from plasma membrane|viral budding from plasma membrane during viral capsid envelopment|plasma membrane viral budding|viral budding from plasma membrane by viral capsid envelopment|plasma membrane viral budding during viral capsid envelopment|virus budding from plasma membrane during viral capsid envelopment										GO:0046767|GO:0046766			biological_process											owl:Class	
GO:0018561	biolink:NamedThing	2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity	Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0457		molecular_function											owl:Class	
GO:0033193	biolink:NamedThing	Lsd1/2 complex	A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast.	got7fsn_ti	Swm1/2 complex|SAPHIRE complex|Swm complex													cellular_component											owl:Class	
GO:0097658	biolink:NamedThing	Asi complex	A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p.	got7fsn_ti							pr	2014-09-29T15:08:29Z						cellular_component											owl:Class	
GO:0102891	biolink:NamedThing	2'4'6'34-pentahydroxychalcone 4'-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone <=> H+ + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-8455|EC:2.4.1.286|RHEA:34295		molecular_function											owl:Class	
GO:0060878	biolink:NamedThing	pouch outgrowth involved in semicircular canal formation	The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.	got7fsn_ti							dph	2009-08-13T10:01:01Z						biological_process											owl:Class	
GO:0050150	biolink:NamedThing	o-pyrocatechuate decarboxylase activity	Catalysis of the reaction: 2,3-dihydroxybenzoate + H(+) = catechol + CO(2).	got7fsn_ti	2,3-dihydroxybenzoate decarboxylase activity|2,3-dihydroxybenzoate carboxy-lyase activity|2,3-DHBA decarboxylase activity|2,3-dihydroxybenzoate carboxy-lyase (catechol-forming)|2,3-dihydroxybenzoic acid decarboxylase activity										GO:0018790	EC:4.1.1.46|RHEA:21492|MetaCyc:O-PYROCATECHUATE-DECARBOXYLASE-RXN|KEGG_REACTION:R00821|UM-BBD_reactionID:r0579		molecular_function											owl:Class	
GO:0047912	biolink:NamedThing	galacturonokinase activity	Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H(+).	got7fsn_ti	galacturonokinase (phosphorylating) D-galacturonic acid kinase activity|ATP:D-galacturonate 1-phosphotransferase activity											MetaCyc:GALACTURONOKINASE-RXN|RHEA:12965|EC:2.7.1.44|KEGG_REACTION:R01980		molecular_function											owl:Class	
GO:0033538	biolink:NamedThing	ajugose biosynthetic process using galactan:galactan galactosyltransferase	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another.	got7fsn_ti	ajugose formation using galactan:galactan galactosyltransferase|ajugose anabolism using galactan:galactan galactosyltransferase|ajugose biosynthesis using galactan:galactan galactosyltransferase|ajugose synthesis using galactan:galactan galactosyltransferase											MetaCyc:PWY-5343		biological_process											owl:Class	
GO:0048510	biolink:NamedThing	regulation of timing of transition from vegetative to reproductive phase	The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.	got7fsn_ti														biological_process											owl:Class	
GO:0102983	biolink:NamedThing	xylogalacturonan beta-1,3-xylosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-xylose + a homogalacturonan <=> UDP + 4 H+ + a xylogalacturonan.	got7fsn_ti												EC:2.4.2.41|MetaCyc:RXN-9589		molecular_function											owl:Class	
GO:0007396	biolink:NamedThing	suture of dorsal opening	Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole.	got7fsn_ti														biological_process											owl:Class	
GO:0070041	biolink:NamedThing	rRNA (uridine-C5-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.	got7fsn_ti														molecular_function											owl:Class	
GO:0052847	biolink:NamedThing	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+.	got7fsn_ti							ai	2011-12-05T11:02:23Z				MetaCyc:RXN-10975		molecular_function											owl:Class	
GO:1902103	biolink:NamedThing	negative regulation of metaphase/anaphase transition of meiotic cell cycle	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.	got7fsn_ti	down-regulation of metaphase/anaphase transition of meiotic cell cycle|down regulation of meiotic metaphase/anaphase transition|negative regulation of meiotic metaphase/anaphase transition|down regulation of metaphase/anaphase transition of meiotic cell cycle|downregulation of metaphase/anaphase transition of meiotic cell cycle|inhibition of meiotic metaphase/anaphase transition|downregulation of meiotic metaphase/anaphase transition|down-regulation of meiotic metaphase/anaphase transition|inhibition of metaphase/anaphase transition of meiotic cell cycle						jl	2013-05-02T12:45:43Z						biological_process											owl:Class	
GO:1905133	biolink:NamedThing	negative regulation of meiotic chromosome separation	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation.	got7fsn_ti	negative regulation of meiotic chromosome resolution|downregulation of meiotic chromosome resolution|down regulation of meiotic chromosome resolution|down regulation of meiotic chromosome separation|downregulation of meiotic chromosome separation|inhibition of meiotic chromosome resolution|down regulation of chromosome separation during meiosis|down-regulation of meiotic chromosome separation|down-regulation of meiotic chromosome resolution|inhibition of meiotic chromosome separation|downregulation of chromosome separation during meiosis|inhibition of chromosome separation during meiosis|negative regulation of chromosome separation during meiosis|down-regulation of chromosome separation during meiosis						dph	2016-04-12T17:46:37Z						biological_process											owl:Class	
GO:0006482	biolink:NamedThing	protein demethylation	The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.	got7fsn_ti	protein amino acid demethylation													biological_process											owl:Class	
GO:0050140	biolink:NamedThing	nitrate reductase (cytochrome) activity	Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite.	got7fsn_ti	ferrocytochrome:nitrate oxidoreductase activity|benzyl viologen-nitrate reductase activity											MetaCyc:NITRATE-REDUCTASE-CYTOCHROME-RXN|EC:1.9.6.1|RHEA:12909		molecular_function											owl:Class	
GO:0016677	biolink:NamedThing	oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.	got7fsn_ti	oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor											EC:1.9.6.-		molecular_function											owl:Class	
GO:1990272	biolink:NamedThing	anti-Mullerian hormone receptor activity	Combining with anti-Mullerian hormone to initiate a change in cell activity.	got7fsn_ti					An example of this is Amdh2 in M. musculus, UniprotKB:Q8K592-1 in PMID:23624077.		hjd	2014-01-14T21:41:35Z						molecular_function											owl:Class	
GO:0050615	biolink:NamedThing	1,2-dihydrovomilenine reductase activity	Catalysis of the reaction: 17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + H(+) + NADPH.	got7fsn_ti	17-O-acetylnorajmaline:NADP+ oxidoreductase activity											KEGG_REACTION:R05879|RHEA:12320|EC:1.3.1.73|MetaCyc:1.3.1.73-RXN		molecular_function											owl:Class	
GO:0043512	biolink:NamedThing	inhibin A complex	Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit.	got7fsn_ti					Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'.									cellular_component											owl:Class	
GO:0043511	biolink:NamedThing	inhibin complex	Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B.	got7fsn_ti					Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'.									cellular_component											owl:Class	
GO:0052893	biolink:NamedThing	N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide.	got7fsn_ti	polyamine oxidase (propane-1,3-diamine-forming) activity											RHEA:25996|MetaCyc:RXN-10465|EC:1.5.3.14		molecular_function											owl:Class	
GO:0048815	biolink:NamedThing	hermaphrodite genitalia morphogenesis	The process in which the anatomical structures of hermaphrodite genitalia are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0036397	biolink:NamedThing	formate dehydrogenase (quinone) activity	Catalysis of the reaction: formate + a quinone = CO2 + a quinol.	got7fsn_ti	Fdh-N activity|formate:quinone oxidoreductase activity|formate dehydrogenase-N activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.1.5.6.		bf	2013-07-18T13:11:41Z				MetaCyc:FORMATEDEHYDROG-RXN|EC:1.17.5.3|KEGG_REACTION:R09494|RHEA:48592		molecular_function											owl:Class	
GO:0008877	biolink:NamedThing	glucose-1-phosphatase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.	got7fsn_ti	alpha-D-glucose-1-phosphate phosphohydrolase activity|D-glucose-1-phosphate phosphohydrolase activity											KEGG_REACTION:R00304|MetaCyc:GLUCOSE-1-PHOSPHAT-RXN|RHEA:19933|EC:3.1.3.10		molecular_function											owl:Class	
GO:0061428	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.	got7fsn_ti							dph	2012-02-06T09:26:05Z						biological_process											owl:Class	
GO:0070265	biolink:NamedThing	necrotic cell death	A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.	got7fsn_ti	necrosis|cellular necrosis				Note that the word necrosis has been widely used in earlier literature to describe forms of cell death which are now known by more precise terms, such as apoptosis. Necrosis can occur in a regulated fashion, involving a precise sequence of signals; in this case, consider annotating to GO:0097300 'programmed necrotic cell death' or to its more specific child GO:0070266 'necroptotic process'.									biological_process											owl:Class	
GO:1900609	biolink:NamedThing	F-9775A metabolic process	The chemical reactions and pathways involving F-9775A.	got7fsn_ti	F-9775A metabolism						di	2012-05-15T07:02:27Z						biological_process											owl:Class	
GO:0070358	biolink:NamedThing	actin polymerization-dependent cell motility	A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.	got7fsn_ti	cell motility by actin tail formation													biological_process											owl:Class	
GO:0032589	biolink:NamedThing	neuron projection membrane	The portion of the plasma membrane surrounding a neuron projection.	got7fsn_ti														cellular_component											owl:Class	
GO:0044722	biolink:NamedThing	renal phosphate excretion	The elimination by an organism of phosphate ions in the urine.	got7fsn_ti	renal phosphate ion excretion						jl	2012-10-18T14:54:00Z						biological_process											owl:Class	
GO:1990933	biolink:NamedThing	microtubule cytoskeleton attachment to nuclear envelope	A process in which the microtubule cytoskeleton is attached to the nuclear envelope.	got7fsn_ti							vw	2016-03-17T08:32:37Z						biological_process											owl:Class	
GO:0018677	biolink:NamedThing	pentachlorophenol monooxygenase activity	Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride.	got7fsn_ti	pentachlorophenol dehalogenase activity|pentachlorophenol hydroxylase activity|PcpB|pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating)|pentachlorophenol dechlorinase activity|PCB4MO activity|PCP hydroxylase activity|PCB 4-monooxygenase activity|pentachlorophenol 4-monooxygenase activity											RHEA:18685|EC:1.14.13.50|UM-BBD_enzymeID:e0148|MetaCyc:PCP4MONO-RXN		molecular_function											owl:Class	
GO:0090346	biolink:NamedThing	cellular organofluorine metabolic process	The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.	got7fsn_ti							tb	2010-06-02T10:36:42Z						biological_process											owl:Class	
GO:0090345	biolink:NamedThing	cellular organohalogen metabolic process	The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.	got7fsn_ti							tb	2010-06-02T10:36:42Z						biological_process											owl:Class	
GO:0005011	biolink:NamedThing	macrophage colony-stimulating factor receptor activity	Combining with macrophage colony-stimulating factor (M-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	got7fsn_ti	CSF-1|M-CSF receptor activity|macrophage colony stimulating factor receptor activity|Fms													molecular_function											owl:Class	
GO:1990984	biolink:NamedThing	tRNA demethylase activity	Catalysis of the removal of a methyl group from one or more positions within a tRNA molecule.	got7fsn_ti							sp	2016-10-28T08:38:14Z						molecular_function											owl:Class	
GO:1990321	biolink:NamedThing	collagen type XXII trimer	A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.	got7fsn_ti							bhm	2014-03-14T16:50:05Z						cellular_component											owl:Class	
GO:0043765	biolink:NamedThing	T/G mismatch-specific endonuclease activity	Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine.	got7fsn_ti	DNA mismatch endonuclease|very short patch repair protein|V.EcoKDcm|Vsr mismatch endonuclease													molecular_function											owl:Class	
GO:0048832	biolink:NamedThing	specification of plant organ number	The regionalization process that modulates the quantity of a particular type of plant organ.	got7fsn_ti														biological_process											owl:Class	
GO:0006702	biolink:NamedThing	androgen biosynthetic process	The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.	got7fsn_ti	androgen biosynthesis|androgen synthesis|androgen formation|androgen anabolism													biological_process											owl:Class	
GO:0070397	biolink:NamedThing	wall teichoic acid metabolic process	The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.	got7fsn_ti	wall teichoic acid metabolism|WTA metabolic process													biological_process											owl:Class	
GO:0046395	biolink:NamedThing	carboxylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.	got7fsn_ti	carboxylic acid catabolism|carboxylic acid breakdown|carboxylic acid degradation													biological_process											owl:Class	
GO:0007095	biolink:NamedThing	mitotic G2 DNA damage checkpoint signaling	A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.	got7fsn_ti	regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|signal transduction involved in mitotic G2 DNA damage checkpoint|mitotic G2 DNA damage checkpoint|down-regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|G2 DNA damage checkpoint|positive regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|negative regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|signal transduction involved in mitotic G2/M transition DNA damage checkpoint|down regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|down regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|signal transduction involved in G2 DNA damage checkpoint|regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|inhibition of signal transduction involved in mitotic G2 DNA damage checkpoint|positive regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|signal transduction involved in G2/M transition DNA damage checkpoint|down-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|mitotic cell cycle G2/M transition DNA damage checkpoint|G2/M transition DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072434|GO:0031572|GO:1902504|GO:0072425|GO:1902505|GO:1902506			biological_process											owl:Class	
GO:0010991	biolink:NamedThing	negative regulation of SMAD protein complex assembly	Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.	got7fsn_ti							tb	2009-06-03T11:30:44Z						biological_process											owl:Class	
GO:0015953	biolink:NamedThing	pyrimidine nucleotide interconversion	The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide.	got7fsn_ti														biological_process											owl:Class	
GO:0006220	biolink:NamedThing	pyrimidine nucleotide metabolic process	The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine metabolism|pyrimidine nucleotide metabolism|pyrimidine metabolic process													biological_process											owl:Class	
GO:0106173	biolink:NamedThing	COPII-coated vesicle lumen	The volume enclosed by the membrane of a COPII-coated endocytic vesicle.	got7fsn_ti							hjd	2019-02-11T18:16:22Z						cellular_component											owl:Class	
GO:0000805	biolink:NamedThing	X chromosome	The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males.	got7fsn_ti												Wikipedia:X_chromosome		cellular_component											owl:Class	
GO:0102046	biolink:NamedThing	3,4-dichlorobenzoate-4,5-oxygenase activity	Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor <=> 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-10427		molecular_function											owl:Class	
GO:0018124	biolink:NamedThing	peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone	The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue.	got7fsn_ti												RESID:AA0233		biological_process											owl:Class	
GO:0009446	biolink:NamedThing	putrescine biosynthetic process	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.	got7fsn_ti	putrescine synthesis|putrescine formation|putrescine biosynthesis|putrescine anabolism													biological_process											owl:Class	
GO:0050349	biolink:NamedThing	triacetate-lactonase activity	Catalysis of the reaction: H(2)O + triacetate lactone = triacetate.	got7fsn_ti	triacetolactone lactonohydrolase activity|triacetate lactone hydrolase activity|triacetic acid lactone hydrolase activity|triacetic lactone hydrolase activity|TAL hydrolase activity											EC:3.1.1.38|MetaCyc:TRIACETATE-LACTONASE-RXN|RHEA:22260|KEGG_REACTION:R03702		molecular_function											owl:Class	
GO:0010387	biolink:NamedThing	COP9 signalosome assembly	The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.	got7fsn_ti	signalosome assembly													biological_process											owl:Class	
GO:0001907	biolink:NamedThing	killing by symbiont of host cells	Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	pathogenesis													biological_process											owl:Class	
GO:0080134	biolink:NamedThing	regulation of response to stress	Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		dhl	2009-05-06T04:51:28Z						biological_process											owl:Class	
GO:0030422	biolink:NamedThing	production of siRNA involved in RNA interference	Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.	got7fsn_ti	production of guide RNAs involved in RNA interference|RNA interference, production of guide RNAs|RNA interference, production of siRNA													biological_process											owl:Class	
GO:0008690	biolink:NamedThing	3-deoxy-manno-octulosonate cytidylyltransferase activity	Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.	got7fsn_ti	CMP-3-deoxy-D-manno-octulosonate diphosphorylase activity|CMP-2-keto-3-deoxyoctulosonic acid synthetase activity|cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase activity|2-keto-3-deoxyoctonate cytidylyltransferase activity|CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase activity|CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity|CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase activity|CMP-3-deoxy-D-manno-octulosonate synthetase activity|CMP-KDO synthetase activity|CTP:3-deoxy-manno-octulosonate cytidylyltransferase activity|3-deoxy-D-manno-octulosonate cytidylyltransferase activity											MetaCyc:CPM-KDOSYNTH-RXN|EC:2.7.7.38|RHEA:23448		molecular_function											owl:Class	
GO:0046721	biolink:NamedThing	formic acid secretion	The controlled release of formic acid, HCOOH, by a cell or a tissue.	got7fsn_ti	formate secretion													biological_process											owl:Class	
GO:0071120	biolink:NamedThing	alpha4-beta1 integrin-CD47 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.	got7fsn_ti	ITGA4-ITGB1-CB47 complex						mah	2009-11-13T02:21:10Z						cellular_component											owl:Class	
GO:0071189	biolink:NamedThing	protocadherin-alpha-v7-protocadherin-gamma-a3 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti	Pcdha7-Pcdhga3 complex						mah	2009-11-23T04:24:28Z						cellular_component											owl:Class	
GO:0102448	biolink:NamedThing	rhamnetin 4'-O-methyltransferase activity	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine  <=> ombuin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-13934		molecular_function											owl:Class	
GO:0015640	biolink:NamedThing	peptidoglycan peptide transmembrane transporter activity	Enables the transfer of peptidoglycan peptides from one side of a membrane to the other. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.	got7fsn_ti	muropeptide transporter activity|murein peptide transporter activity													molecular_function											owl:Class	
GO:0015647	biolink:NamedThing	peptidoglycan transmembrane transporter activity	Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other.	got7fsn_ti	murein transporter activity													molecular_function											owl:Class	
GO:0009246	biolink:NamedThing	enterobacterial common antigen biosynthetic process	The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.	got7fsn_ti	enterobacterial common antigen biosynthesis|enterobacterial common antigen formation|enterobacterial common antigen synthesis|enterobacterial common antigen anabolism											MetaCyc:ECASYN-PWY		biological_process											owl:Class	
GO:0043478	biolink:NamedThing	pigment accumulation in response to UV light	The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0098925	biolink:NamedThing	retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission	Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0036319	biolink:NamedThing	mating-type M-factor pheromone receptor activity	Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus.	got7fsn_ti	M-factor receptor activity|M-factor mating pheromone receptor activity						bf	2012-08-30T16:51:12Z						molecular_function											owl:Class	
GO:0000154	biolink:NamedThing	rRNA modification	The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti	rRNA editing				The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.						GO:0016548			biological_process											owl:Class	
GO:0047861	biolink:NamedThing	diiodotyrosine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate.	got7fsn_ti	diiodotyrosine aminotransferase activity|halogenated tyrosine aminotransferase activity|3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase activity|halogenated tyrosine transaminase activity											KEGG_REACTION:R03207|RHEA:19781|EC:2.6.1.24|MetaCyc:DIIODOTYROSINE-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0010282	biolink:NamedThing	senescence-associated vacuole	A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.	got7fsn_ti	senescence associated vacuole													cellular_component											owl:Class	
GO:0030891	biolink:NamedThing	VCB complex	A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.	got7fsn_ti	pVHL-elongin C-elongin B complex|VHL complex|von Hippel-Lindau tumor suppressor complex													cellular_component											owl:Class	
GO:0000153	biolink:NamedThing	cytoplasmic ubiquitin ligase complex	A ubiquitin ligase complex found in the cytoplasm.	got7fsn_ti														cellular_component											owl:Class	
GO:0050271	biolink:NamedThing	S-alkylcysteine lyase activity	Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate.	got7fsn_ti	S-alkyl-L-cysteine lyase activity|alkyl cysteine lyase activity|S-alkyl-L-cysteine sulfoxide lyase activity|S-alkyl-L-cysteine alkylthiol-lyase (deaminating) activity|alkylcysteine lyase activity|S-alkylcysteinase activity|S-alkyl-L-cysteinase activity|S-alkyl-L-cysteine alkylthiol-lyase (deaminating; pyruvate-forming)											MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN|RHEA:22424|EC:4.4.1.6		molecular_function											owl:Class	
GO:0000107	biolink:NamedThing	imidazoleglycerol-phosphate synthase activity	Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+).	got7fsn_ti	imidazole-glycerol-phosphate synthase activity|glutamine amidotransferase:cyclase activity|imidazole glycerol phosphate synthase activity|imidazoleglycerol phosphate synthase activity											RHEA:24793|MetaCyc:GLUTAMIDOTRANS-RXN		molecular_function											owl:Class	
GO:0038151	biolink:NamedThing	CCL2-activated CCR2 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 2 receptor (CCR2) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CCL2/CCR2 signaling pathway						bf	2012-05-11T11:41:58Z						biological_process											owl:Class	
GO:0047233	biolink:NamedThing	N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.	got7fsn_ti	UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase activity											RHEA:13569|MetaCyc:2.4.1.165-RXN|EC:2.4.1.165		molecular_function											owl:Class	
GO:0099528	biolink:NamedThing	G protein-coupled neurotransmitter receptor activity	Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G-protein coupled neurotransmitter receptor activity													molecular_function											owl:Class	
GO:0061480	biolink:NamedThing	response to asparaginase	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus.	got7fsn_ti							dph	2012-11-07T09:13:08Z						biological_process											owl:Class	
GO:1990634	biolink:NamedThing	protein phosphatase 5 binding	Binding to protein phosphatase 5.	got7fsn_ti	protein phosphatase T binding						sl	2015-02-10T21:30:41Z						molecular_function											owl:Class	
GO:0046592	biolink:NamedThing	polyamine oxidase activity	Catalysis of the oxidative degradation or interconversion of polyamines.	got7fsn_ti	N1-acetylspermidine:oxygen oxidoreductase (deaminating)|1-N-acetylspermidine:oxygen oxidoreductase (deaminating)											MetaCyc:POLYAMINE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0016847	biolink:NamedThing	1-aminocyclopropane-1-carboxylate synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+).	got7fsn_ti	aminocyclopropanecarboxylic acid synthase activity|S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)|ACC synthase activity|1-aminocyclopropanecarboxylate synthase activity|L-VG deaminase activity|S-adenosyl-L-methionine methylthioadenosine-lyase activity|1-aminocyclopropane-1-carboxylate synthetase activity|aminocyclopropanecarboxylate synthase activity|1-aminocyclopropane-1-carboxylic acid synthase activity|L-vinylglycine deaminase activity				Note that this function was formerly EC:4.1.99.4.						GO:0034100	RHEA:21744|EC:4.4.1.14|MetaCyc:4.4.1.14-RXN|KEGG_REACTION:R00179		molecular_function											owl:Class	
GO:0008324	biolink:NamedThing	cation transmembrane transporter activity	Enables the transfer of cation from one side of a membrane to the other.	got7fsn_ti	transmembrane cation transporter activity													molecular_function											owl:Class	
GO:0044473	biolink:NamedThing	envenomation resulting in negative regulation of calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:19:46Z						biological_process											owl:Class	
GO:0032023	biolink:NamedThing	trypsinogen activation	The proteolytic processing of trypsinogen to the active form, trypsin.	got7fsn_ti	cleavage of trypsinogen to trypsin													biological_process											owl:Class	
GO:0098725	biolink:NamedThing	symmetric cell division	Cell division in which both daughter cells are of the same type.	got7fsn_ti														biological_process											owl:Class	
GO:0098900	biolink:NamedThing	regulation of action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti					The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term.									biological_process											owl:Class	
GO:0051292	biolink:NamedThing	nuclear pore complex assembly	The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.	got7fsn_ti	nuclear pore biosynthesis|nuclear pore formation|NPC assembly|nuclear pore complex formation|nuclear pore complex biogenesis|nuclear pore biogenesis|nuclear pore assembly|nuclear pore complex biosynthesis													biological_process											owl:Class	
GO:0102896	biolink:NamedThing	colnelenate synthase activity	Catalysis of the reaction: (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate <=> colnelenate + H2O.	got7fsn_ti												RHEA:28178|MetaCyc:RXN-8498		molecular_function											owl:Class	
GO:0048672	biolink:NamedThing	positive regulation of collateral sprouting	Any process that activates or increases the frequency, rate or extent of collateral sprouting.	got7fsn_ti	stimulation of collateral sprouting|up-regulation of collateral sprouting|activation of collateral sprouting|up regulation of collateral sprouting|upregulation of collateral sprouting													biological_process											owl:Class	
GO:0050772	biolink:NamedThing	positive regulation of axonogenesis	Any process that activates or increases the frequency, rate or extent of axonogenesis.	got7fsn_ti	up regulation of axonogenesis|stimulation of axonogenesis|up-regulation of axonogenesis|upregulation of axonogenesis|activation of axonogenesis													biological_process											owl:Class	
GO:0010689	biolink:NamedThing	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0140239	biolink:NamedThing	postsynaptic endocytosis	A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.	got7fsn_ti		https://github.com/geneontology/synapse/issues/230			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T07:38:27Z						biological_process											owl:Class	
GO:0042403	biolink:NamedThing	thyroid hormone metabolic process	The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.	got7fsn_ti	thyroid hormone metabolism													biological_process											owl:Class	
GO:0031289	biolink:NamedThing	actin phosphorylation	The transfer of one or more phosphate groups to an actin molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0140469	biolink:NamedThing	GCN2-mediated signaling	A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation.	got7fsn_ti	regulation of eIF2 alpha phosphorylation by amino acid starvation|EIF2AK4-mediated signaling	https://github.com/geneontology/go-ontology/issues/15399|https://github.com/geneontology/go-ontology/issues/19153					pg	2020-05-26T08:47:25Z			GO:0060733			biological_process											owl:Class	
GO:0102559	biolink:NamedThing	protein-(glutamine-N5) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine  + H+ + a [release factor]-N5-methyl-L-glutamine.	got7fsn_ti												MetaCyc:RXN-14992|EC:2.1.1.297|RHEA:42896		molecular_function											owl:Class	
GO:0042123	biolink:NamedThing	glucanosyltransferase activity	Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation.	got7fsn_ti														molecular_function											owl:Class	
GO:0002269	biolink:NamedThing	leukocyte activation involved in inflammatory response	A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.	got7fsn_ti	immune cell activation during inflammatory response|leukocyte activation during inflammatory response													biological_process											owl:Class	
GO:0051634	biolink:NamedThing	inhibition of acetylcholine uptake	Any process that prevents the activation of the directed movement of acetylcholine into a cell.	got7fsn_ti	inhibition of acetylcholine import													biological_process											owl:Class	
GO:0002077	biolink:NamedThing	acrosome matrix dispersal	The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0021729	biolink:NamedThing	superior reticular formation development	The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0031038	biolink:NamedThing	myosin II filament organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.	got7fsn_ti	myosin II polymerization or depolymerization|myosin II filament assembly or disassembly|myosin II filament organisation													biological_process											owl:Class	
GO:0021796	biolink:NamedThing	cerebral cortex regionalization	The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops.	got7fsn_ti	cerebral cortex pattern formation|cerebral cortex pattern biosynthesis|cerebral cortex arealization													biological_process											owl:Class	
GO:0043265	biolink:NamedThing	ectoplasm	Granule free cytoplasm, lying immediately below the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0030497	biolink:NamedThing	fatty acid elongation	The elongation of a fatty acid chain by the sequential addition of two-carbon units.	got7fsn_ti														biological_process											owl:Class	
GO:0046165	biolink:NamedThing	alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.	got7fsn_ti	alcohol biosynthesis|alcohol anabolism|alcohol formation|alcohol synthesis													biological_process											owl:Class	
GO:0008391	biolink:NamedThing	arachidonic acid monooxygenase activity	Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.	got7fsn_ti	cytochrome P450 CYP2B19													molecular_function											owl:Class	
GO:0071569	biolink:NamedThing	protein ufmylation	Covalent attachment of the ubiquitin-like protein UFM1 to another protein.	got7fsn_ti							mah	2010-01-20T04:12:01Z						biological_process											owl:Class	
GO:0034082	biolink:NamedThing	type II polyketide synthase complex	A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction.	got7fsn_ti	type II polyketide synthase|type II PKS|type II PKS complex													cellular_component											owl:Class	
GO:0003047	biolink:NamedThing	regulation of systemic arterial blood pressure by epinephrine	The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine.	got7fsn_ti	blood pressure regulation by epinephrine|regulation of blood pressure by adrenaline													biological_process											owl:Class	
GO:0051699	biolink:NamedThing	proline oxidase activity	Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2.	got7fsn_ti												RHEA:26124|MetaCyc:RXN-821		molecular_function											owl:Class	
GO:0030947	biolink:NamedThing	regulation of vascular endothelial growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.	got7fsn_ti	regulation of VEGF receptor signaling pathway|regulation of VEGF receptor signalling pathway|regulation of vascular endothelial growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0090287	biolink:NamedThing	regulation of cellular response to growth factor stimulus	Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	got7fsn_ti							tb	2010-02-18T03:01:25Z						biological_process											owl:Class	
GO:0070501	biolink:NamedThing	poly-gamma-glutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.	got7fsn_ti	poly-gamma-glutamate formation|poly-gamma-glutamate synthesis|poly-gamma-glutamate anabolism|poly-gamma-glutamate biosynthesis													biological_process											owl:Class	
GO:0048156	biolink:NamedThing	tau protein binding	Binding to tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.	got7fsn_ti														molecular_function											owl:Class	
GO:0060818	biolink:NamedThing	inactivation of paternal X chromosome by genetic imprinting	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genetic imprinting.	got7fsn_ti							dph	2009-08-11T10:52:31Z						biological_process											owl:Class	
GO:0072063	biolink:NamedThing	short descending thin limb development	The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.	got7fsn_ti							mah	2010-01-25T04:12:39Z						biological_process											owl:Class	
GO:0046290	biolink:NamedThing	isoflavonoid phytoalexin catabolic process	The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.	got7fsn_ti	isoflavonoid phytoalexin catabolism|isoflavonoid phytoalexin breakdown|isoflavonoid phytoalexin degradation													biological_process											owl:Class	
GO:0046288	biolink:NamedThing	isoflavonoid catabolic process	The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.	got7fsn_ti	isoflavonoid breakdown|isoflavonoid catabolism|isoflavonoid degradation													biological_process											owl:Class	
GO:0039591	biolink:NamedThing	suppression by virus of host tapasin activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host tapasin (TAP binding protein/TAPBP) activity. Tapasin is a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response.	got7fsn_ti	inhibition of host TAPBP by virus|inhibition of host tapasin by virus|suppression by virus of host TAP binding protein				Consider also annotating to 'tapasin binding ; GO:0046980'.		bf	2012-06-25T01:27:48Z				VZ:818		biological_process											owl:Class	
GO:0046776	biolink:NamedThing	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.	got7fsn_ti	negative regulation by virus of MHC class I cell surface presentation|suppression by virus of MHC class I cell surface presentation in host|major histocompatibility complex|inhibition of host MHC class I molecule presentation by virus|suppression by virus of host MHC class I cell surface presentation											VZ:819		biological_process											owl:Class	
GO:0036216	biolink:NamedThing	cellular response to stem cell factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.	got7fsn_ti	cellular response to KIT ligand|cellular response to SCF|cellular response to KITLG|cellular response to hematopoietic growth factor KL						bf	2012-04-27T10:30:53Z						biological_process											owl:Class	
GO:1901994	biolink:NamedThing	negative regulation of meiotic cell cycle phase transition	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition.	got7fsn_ti	downregulation of cell cycle transition|inhibition of cell cycle transition|negative regulation of cell cycle transition|down regulation of meiotic cell cycle phase transition|down-regulation of cell cycle transition|down-regulation of meiotic cell cycle phase transition|down regulation of cell cycle transition|downregulation of meiotic cell cycle phase transition|inhibition of meiotic cell cycle phase transition						jl	2013-03-19T16:15:03Z						biological_process											owl:Class	
GO:0035780	biolink:NamedThing	CD80 biosynthetic process	The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.	got7fsn_ti	CD80 synthesis|CD80 formation|CD80 biosynthesis|CD80 anabolism						bf	2011-04-04T11:18:41Z						biological_process											owl:Class	
GO:0047098	biolink:NamedThing	Latia-luciferin monooxygenase (demethylating) activity	Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.	got7fsn_ti	Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating)|Latia luciferin monooxygenase (demethylating)|luciferase (Latia luciferin)											MetaCyc:1.14.99.21-RXN|RHEA:12677|EC:1.14.99.21		molecular_function											owl:Class	
GO:0031757	biolink:NamedThing	Edg-4 lysophosphatidic acid receptor binding	Binding to an Edg-4 lysophosphatidic acid receptor.	got7fsn_ti	Edg-4 lysophosphatidic acid receptor ligand|LPA2 receptor binding													molecular_function											owl:Class	
GO:0008979	biolink:NamedThing	prophage integrase activity	Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA.	got7fsn_ti	integrase activity involved in establishment of integrated proviral latency													molecular_function											owl:Class	
GO:0009009	biolink:NamedThing	site-specific recombinase activity	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique target DNA sequences.	got7fsn_ti	RecA-family recombinase activity	https://github.com/geneontology/go-ontology/issues/3917			Note that this term is not a child of 'recombinase activity ; GO:0000150' because the latter represents activities that do not break or form phosphodiester bonds.									molecular_function											owl:Class	
GO:0036446	biolink:NamedThing	myofibroblast differentiation	The process in which an undifferentiated cell acquires the features of a myofibroblast cell.	got7fsn_ti	myofibroblast cell differentiation						bf	2013-10-30T10:06:51Z						biological_process											owl:Class	
GO:0099002	biolink:NamedThing	viral genome ejection through host cell envelope, short tail mechanism	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins.  Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties.	got7fsn_ti	viral short tail ejection system											VZ:3954		biological_process											owl:Class	
GO:0140043	biolink:NamedThing	lipid droplet localization to prospore membrane leading edge	Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge.	got7fsn_ti	lipid body localization to ascospore-type prospore membrane leading edge|adiposome localization to forespore membrane leading edge|lipid body localization to FSM membrane leading edge|adiposome localization to ascospore-type prospore membrane leading edge|adiposome localization to FSM membrane leading edge|lipid particle localization to FSM membrane leading edge|lipid particle localization to ascospore-type prospore membrane leading edge|lipid particle localization to forespore membrane leading edge|lipid body localization to forespore membrane leading edge						pg	2017-06-19T09:20:13Z						biological_process											owl:Class	
GO:0030221	biolink:NamedThing	basophil differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.	got7fsn_ti	basophil cell differentiation													biological_process											owl:Class	
GO:0060414	biolink:NamedThing	aorta smooth muscle tissue morphogenesis	The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.	got7fsn_ti														biological_process											owl:Class	
GO:0043185	biolink:NamedThing	vascular endothelial growth factor receptor 3 binding	Binding to a vascular endothelial growth factor receptor 3.	got7fsn_ti	VEGF receptor 3 binding|VEGFR 3 binding|fms-like-tyrosine kinase (Flt)-4 binding													molecular_function											owl:Class	
GO:0000224	biolink:NamedThing	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity	Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.	got7fsn_ti	N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity|glycopeptide N-glycosidase activity|glycopeptidase activity|jack-bean glycopeptidase|PNGase F|N-oligosaccharide glycopeptidase activity|peptide:N-glycanase|N-glycanase activity|PNGase A|PNGase											Reactome:R-HSA-8850594|MetaCyc:3.5.1.52-RXN|EC:3.5.1.52		molecular_function											owl:Class	
GO:0043441	biolink:NamedThing	acetoacetic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.	got7fsn_ti	acetoacetic acid formation|acetoacetic acid synthesis|acetoacetic acid anabolism|acetoacetic acid biosynthesis													biological_process											owl:Class	
GO:0051790	biolink:NamedThing	short-chain fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6.	got7fsn_ti	short-chain fatty acid formation|short chain fatty acid biosynthetic process|short-chain fatty acid anabolism|short-chain fatty acid synthesis|short-chain fatty acid biosynthesis|short chain fatty acid biosynthesis													biological_process											owl:Class	
GO:1990343	biolink:NamedThing	heterochromatin domain	A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).	got7fsn_ti	HOOD				An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin domains preferentially assemble at sexual differentiation genes and retrotransposons.		mah	2014-03-21T15:40:48Z						cellular_component											owl:Class	
GO:0045903	biolink:NamedThing	positive regulation of translational fidelity	Any process that increases the ability of the translational apparatus to interpret the genetic code.	got7fsn_ti	up regulation of translational fidelity|activation of translational fidelity|upregulation of translational fidelity|up-regulation of translational fidelity|stimulation of translational fidelity													biological_process											owl:Class	
GO:0052102	biolink:NamedThing	positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	upregulation by symbiont of defense-related host calcium-dependent protein kinase pathway|positive regulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction|up regulation by symbiont of defense-related host calcium-dependent protein kinase pathway|stimulation by symbiont of defense-related host calcium-dependent protein kinase pathway|up-regulation by symbiont of defense-related host calcium-dependent protein kinase pathway|positive regulation of defense-related host CDPK pathway by organism|activation by symbiont of defense-related host calcium-dependent protein kinase pathway										GO:0052287			biological_process											owl:Class	
GO:0016309	biolink:NamedThing	1-phosphatidylinositol-5-phosphate 4-kinase activity	Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	got7fsn_ti	1-phosphatidylinositol-5-phosphate kinase|ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity|type II PIP kinase activity|PIP4K											Reactome:R-HSA-6811522|Reactome:R-HSA-1675776|EC:2.7.1.149|RHEA:12280|MetaCyc:2.7.1.149-RXN		molecular_function											owl:Class	
GO:0090135	biolink:NamedThing	actin filament branching	The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments.	got7fsn_ti							tb	2009-12-08T01:53:14Z						biological_process											owl:Class	
GO:0051356	biolink:NamedThing	visual perception involved in equilibrioception	The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.	got7fsn_ti	perception of orientation with respect to gravity by visual perception|equilibrioception by visual perception|visual perception during equilibrioception													biological_process											owl:Class	
GO:0007601	biolink:NamedThing	visual perception	The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.	got7fsn_ti	sense of sight|sensory visual perception|vision											Wikipedia:Visual_perception		biological_process											owl:Class	
GO:0017180	biolink:NamedThing	peptidyl-diphthine biosynthetic process from peptidyl-histidine	The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine.	got7fsn_ti	peptidyl-diphthine anabolism from peptidyl-histidine|peptidyl-diphthine formation from peptidyl-histidine|peptidyl-diphthine synthesis from peptidyl-histidine													biological_process											owl:Class	
GO:0035291	biolink:NamedThing	specification of segmental identity, intercalary segment	The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti					See also the fly_anatomy.ontology term 'intercalary segment ; FBbt:00000010'.									biological_process											owl:Class	
GO:0097702	biolink:NamedThing	response to oscillatory fluid shear stress	Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis.	got7fsn_ti							pr	2016-01-27T14:17:08Z						biological_process											owl:Class	
GO:0046333	biolink:NamedThing	octopamine metabolic process	The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.	got7fsn_ti	octopamine metabolism													biological_process											owl:Class	
GO:0019398	biolink:NamedThing	gallate catabolic process via gallate dioxygenase activity	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase.	got7fsn_ti	gallate breakdown via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallate catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallate degradation via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallic acid catabolism via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallic acid catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate											MetaCyc:GALLATE-DEGRADATION-II-PWY		biological_process											owl:Class	
GO:0042195	biolink:NamedThing	aerobic gallate catabolic process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen.	got7fsn_ti	aerobic gallic acid catabolism|aerobic gallate degradation|aerobic gallate breakdown|aerobic gallic acid catabolic process|aerobic gallate catabolism													biological_process											owl:Class	
GO:0007492	biolink:NamedThing	endoderm development	The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0007185	biolink:NamedThing	transmembrane receptor protein tyrosine phosphatase signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	transmembrane receptor protein tyrosine phosphatase signalling pathway													biological_process											owl:Class	
GO:0007167	biolink:NamedThing	enzyme linked receptor protein signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	enzyme linked receptor protein signalling pathway													biological_process											owl:Class	
GO:0099539	biolink:NamedThing	neuropeptide secretion from presynapse	The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration.	got7fsn_ti	neuropeptide secretion from presynapse via dense core granule exocytosis													biological_process											owl:Class	
GO:0047402	biolink:NamedThing	protein-glucosylgalactosylhydroxylysine glucosidase activity	Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.	got7fsn_ti	2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase activity|protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase activity											MetaCyc:3.2.1.107-RXN|RHEA:11068|EC:3.2.1.107		molecular_function											owl:Class	
GO:0016437	biolink:NamedThing	tRNA cytidylyltransferase activity	Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1).	got7fsn_ti	tRNA adenylyl(cytidylyl)transferase|tRNA CCA-diphosphorylase activity|tRNA CCA-pyrophosphorylase activity|CTP(ATP):tRNA nucleotidyltransferase|ATP(CTP)-tRNA nucleotidyltransferase|ribonucleic cytidylyltransferase|ATP (CTP):tRNA nucleotidyltransferase|transfer ribonucleate nucleotidyltransferase|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase|transfer ribonucleate adenylyltransferase|transfer ribonucleic acid nucleotidyl transferase|CTP:tRNA cytidylyltransferase activity|-C-C-A pyrophosphorylase|ATP(CTP):tRNA nucleotidyltransferase activity|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase|transfer RNA adenylyltransferase|transfer ribonucleic adenylyl (cytidylyl) transferase|transfer ribonucleate cytidylyltransferase|transfer-RNA nucleotidyltransferase											EC:2.7.7.72|MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0001596	biolink:NamedThing	angiotensin type I receptor activity	An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.	got7fsn_ti	PLC-activating angiotensin receptor activity													molecular_function											owl:Class	
GO:0000036	biolink:NamedThing	acyl carrier activity	Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.	got7fsn_ti	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process													molecular_function											owl:Class	
GO:0018607	biolink:NamedThing	1-indanone monooxygenase activity	Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin.	got7fsn_ti												UM-BBD_reactionID:r0417|EC:1.14.12.-		molecular_function											owl:Class	
GO:0051433	biolink:NamedThing	BH2 domain binding	Binding to a BH2 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.	got7fsn_ti														molecular_function											owl:Class	
GO:0035812	biolink:NamedThing	renal sodium excretion	The elimination by an organism of sodium in the urine.	got7fsn_ti							bf	2011-04-20T01:24:16Z						biological_process											owl:Class	
GO:0050414	biolink:NamedThing	formimidoylaspartate deiminase activity	Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3.	got7fsn_ti	N-formimidoyl-L-aspartate iminohydrolase activity|formiminoaspartate deiminase activity											MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN|EC:3.5.3.5|RHEA:13661		molecular_function											owl:Class	
GO:0032393	biolink:NamedThing	MHC class I receptor activity	Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.	got7fsn_ti	T cell receptor activity|gamma-delta T cell receptor activity|alpha-beta T cell receptor activity				Note that this term is intended for annotation of gene products that act as receptors for MHC class I protein complexes, not for components of the MHC class I protein complexes themselves.									molecular_function											owl:Class	
GO:0097246	biolink:NamedThing	catechin binding	Binding to a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure.	got7fsn_ti							pr	2012-02-17T03:53:54Z						molecular_function											owl:Class	
GO:0097245	biolink:NamedThing	flavanol binding	Binding to a flavanol.	got7fsn_ti	flavan-3-ol binding						pr	2012-02-17T03:52:10Z						molecular_function											owl:Class	
GO:0030643	biolink:NamedThing	cellular phosphate ion homeostasis	Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0072502	biolink:NamedThing	cellular trivalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of trivalent inorganic anions at the level of a cell.	got7fsn_ti					Note that this term was split from 'cellular di-, tri-valent inorganic anion homeostasis ; GO:0030319' (sibling term 'cellular divalent inorganic anion homeostasis' ; GO:0072501').		mah	2010-12-16T12:53:42Z						biological_process											owl:Class	
GO:0106282	biolink:NamedThing	isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity	Catalysis of the reaction: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH.	got7fsn_ti							hjd	2020-07-29T17:51:00Z				RHEA:42024		molecular_function											owl:Class	
GO:0019400	biolink:NamedThing	alditol metabolic process	The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.	got7fsn_ti	alditol metabolism													biological_process											owl:Class	
GO:0010270	biolink:NamedThing	photosystem II oxygen evolving complex assembly	The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ.	got7fsn_ti	OEC (PSII) ASSEMBLY													biological_process											owl:Class	
GO:0018732	biolink:NamedThing	sulfolactone hydrolase activity	Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate.	got7fsn_ti	sulpholactone hydrolase activity											EC:3.1.1.92|UM-BBD_reactionID:r0583		molecular_function											owl:Class	
GO:0008882	biolink:NamedThing	[glutamate-ammonia-ligase] adenylyltransferase activity	Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)].	got7fsn_ti	glutamate-ammonia-ligase adenylyltransferase activity|adenosine triphosphate:glutamine synthetase adenylyltransferase activity|ATP:glutamine synthetase adenylyltransferase activity|glutamine-synthetase adenylyltransferase activity|ATP:[glutamate-ammonia-ligase] adenylyltransferase activity|ATP:L-glutamate:ammonia ligase (ADP-forming) adenylyltransferase activity											MetaCyc:GSADENYLATION-RXN|EC:2.7.7.42|RHEA:18589		molecular_function											owl:Class	
GO:0102584	biolink:NamedThing	cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP-alpha-D-glucose <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-15330		molecular_function											owl:Class	
GO:0052774	biolink:NamedThing	glucosyl-N-acetylglucosamine glucosaminidase activity	Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine.	got7fsn_ti							ai	2011-10-03T12:01:05Z						molecular_function											owl:Class	
GO:0080169	biolink:NamedThing	cellular response to boron-containing substance deprivation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances.	got7fsn_ti	cellular response to boron starvation|cellular response to boron deprivation						dhl	2010-09-23T05:10:00Z						biological_process											owl:Class	
GO:0045051	biolink:NamedThing	protein insertion into ER membrane by internal uncleaved signal-anchor sequence	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences.	got7fsn_ti	protein-endoplasmic reticulum insertion by internal uncleaved signal-anchor sequence|protein insertion into ER membrane, internal uncleaved signal-anchor sequence mediated|internal uncleaved signal-anchor sequence mediated protein insertion into ER membrane|protein-ER insertion by internal uncleaved signal-anchor sequence|protein insertion into endoplasmic reticulum membrane by internal uncleaved signal-anchor sequence													biological_process											owl:Class	
GO:0045771	biolink:NamedThing	negative regulation of autophagosome size	Any process that reduces autophagosome size.	got7fsn_ti	down-regulation of autophagic vacuole size|down regulation of autophagic vacuole size|downregulation of autophagic vacuole size|inhibition of autophagic vacuole size|negative regulation of autophagic vacuole size													biological_process											owl:Class	
GO:0097419	biolink:NamedThing	Pick body	Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E.	got7fsn_ti							pr	2012-11-06T20:57:02Z				NIF_Subcellular:nlx_subcell_20090102		cellular_component											owl:Class	
GO:0110050	biolink:NamedThing	deaminated glutathione amidase activity	Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H(2)O = 2-oxoglutarate + L-cysteinylglycine.	got7fsn_ti					N-(4-oxoglutarate)-L-cysteinylglycine = deaminated glutathione		kmv	2017-08-31T19:19:11Z						molecular_function											owl:Class	
GO:0102707	biolink:NamedThing	S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity	Catalysis of the reaction: beta-alanine + S-adenosyl-L-methionine  = H+ + N-methyl-beta-alanine + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.49|MetaCyc:RXN-6461		molecular_function											owl:Class	
GO:0071961	biolink:NamedThing	mitotic sister chromatid cohesion, arms	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis.	got7fsn_ti	sister chromatid cohesion along arms at mitosis|mitotic sister chromatid cohesion along arms						mah	2011-06-02T11:21:13Z						biological_process											owl:Class	
GO:0007064	biolink:NamedThing	mitotic sister chromatid cohesion	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.	got7fsn_ti														biological_process											owl:Class	
GO:0071465	biolink:NamedThing	cellular response to desiccation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.	got7fsn_ti	desiccation tolerance						mah	2009-12-18T11:35:19Z						biological_process											owl:Class	
GO:0070715	biolink:NamedThing	sodium-dependent organic cation transport	The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							mah	2009-06-09T03:26:27Z						biological_process											owl:Class	
GO:0045734	biolink:NamedThing	regulation of acetate catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.	got7fsn_ti	regulation of acetate degradation|regulation of acetate breakdown|regulation of acetate catabolism													biological_process											owl:Class	
GO:0016513	biolink:NamedThing	core-binding factor complex	A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.	got7fsn_ti	PEPB2 complex|CBF complex|AML1 complex													cellular_component											owl:Class	
GO:0075132	biolink:NamedThing	suppression by symbiont of host protein kinase-mediated signal transduction	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host protein kinase-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075101".									biological_process											owl:Class	
GO:0021645	biolink:NamedThing	vagus nerve structural organization	The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	got7fsn_ti	vagus nerve structural organisation|CN X structural organization													biological_process											owl:Class	
GO:0070437	biolink:NamedThing	Grb2-Shc complex	A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway.	got7fsn_ti	Grb2-Shc complex, EGF stimulated													cellular_component											owl:Class	
GO:0004723	biolink:NamedThing	calcium-dependent protein serine/threonine phosphatase activity	Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.	got7fsn_ti	calcium-dependent protein serine/threonine phosphatase, intrinsic catalyst activity|calcineurin										GO:0008596	Reactome:R-HSA-2025882		molecular_function											owl:Class	
GO:0008254	biolink:NamedThing	3'-nucleotidase activity	Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.	got7fsn_ti	3'-ribonucleotidase activity|3' nucleotidase activity|3'-ribonucleotide phosphohydrolase activity|3'-phosphatase activity|3'-mononucleotidase activity											RHEA:10144|EC:3.1.3.6|MetaCyc:3-NUCLEOTID-RXN		molecular_function											owl:Class	
GO:0098534	biolink:NamedThing	centriole assembly	A cellular process that results in the assembly of one or more centrioles.	got7fsn_ti							dos	2013-10-22T15:55:22Z						biological_process											owl:Class	
GO:0034441	biolink:NamedThing	plasma lipoprotein particle oxidation	The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids.	got7fsn_ti	plasma lipoprotein oxidation													biological_process											owl:Class	
GO:0034369	biolink:NamedThing	plasma lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).	got7fsn_ti														biological_process											owl:Class	
GO:0017105	biolink:NamedThing	acyl-CoA delta11-desaturase activity	Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta11-acyl-CoA + acceptor + 2 H2O. The enzyme introduces a cis double bond at position C-11 of saturated fatty acyl-CoAs.	got7fsn_ti	acyl-CoA delta(11)-desaturase activity|acyl-CoA D11-desaturase activity											EC:1.14.19.5		molecular_function											owl:Class	
GO:0047387	biolink:NamedThing	serine-ethanolaminephosphate phosphodiesterase activity	Catalysis of the reaction: H(2)O + serine phosphoethanolamine = H(+) + phosphoethanolamine + serine.	got7fsn_ti	SEP diesterase activity|serine ethanolamine phosphodiester phosphodiesterase activity|serine-phosphoethanolamine ethanolaminephosphohydrolase activity											MetaCyc:3.1.4.13-RXN|EC:3.1.4.13|KEGG_REACTION:R02817|RHEA:17113		molecular_function											owl:Class	
GO:0009992	biolink:NamedThing	cellular water homeostasis	Any process involved in the maintenance of an internal steady state of water within a cell.	got7fsn_ti	cellular osmoregulation													biological_process											owl:Class	
GO:0032330	biolink:NamedThing	regulation of chondrocyte differentiation	Any process that modulates the frequency, rate or extent of chondrocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0061339	biolink:NamedThing	establishment or maintenance of monopolar cell polarity	Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.	got7fsn_ti							dph	2010-09-29T09:10:05Z						biological_process											owl:Class	
GO:0052825	biolink:NamedThing	inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate.	got7fsn_ti								2011-11-29T09:49:22Z				Reactome:R-HSA-1855219		molecular_function											owl:Class	
GO:0018595	biolink:NamedThing	alpha-pinene monooxygenase activity	Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol.	got7fsn_ti												UM-BBD_reactionID:r0716|EC:1.14.13.155|RHEA:32891		molecular_function											owl:Class	
GO:1990830	biolink:NamedThing	cellular response to leukemia inhibitory factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.	got7fsn_ti	cellular response to CDF|cellular response to cholinergic differentiation factor						sl	2015-08-20T19:30:38Z						biological_process											owl:Class	
GO:0090716	biolink:NamedThing	adaptive immune memory response	An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.	got7fsn_ti							tb	2016-11-11T12:32:42Z						biological_process											owl:Class	
GO:0016525	biolink:NamedThing	negative regulation of angiogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.	got7fsn_ti	downregulation of angiogenesis|inhibition of angiogenesis|down regulation of angiogenesis|down-regulation of angiogenesis													biological_process											owl:Class	
GO:2000181	biolink:NamedThing	negative regulation of blood vessel morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis.	got7fsn_ti							dph	2010-10-13T12:46:31Z						biological_process											owl:Class	
GO:0060857	biolink:NamedThing	establishment of glial blood-brain barrier	Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.	got7fsn_ti	establishment of glial blood/brain barrier|establishment of glial BBB						dph	2009-08-12T12:17:51Z						biological_process											owl:Class	
GO:0120319	biolink:NamedThing	long-chain fatty acid omega-1 hydroxylase activity	Catalysis of the reaction: an (omega-1)-ethyl long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase.	got7fsn_ti	cytochrome P450 fatty acid omega-1 hydroxylase activity	https://github.com/geneontology/go-ontology/issues/21648					krc	2021-06-21T18:31:38Z				RHEA:60936		molecular_function											owl:Class	
GO:0070274	biolink:NamedThing	RES complex	A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.	got7fsn_ti	pre-mRNA retention and splicing complex													cellular_component											owl:Class	
GO:0032059	biolink:NamedThing	bleb	A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.	got7fsn_ti	plasma membrane bleb											Wikipedia:Bleb_(cell_biology)		cellular_component											owl:Class	
GO:0102404	biolink:NamedThing	linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity	Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O <=> vicianose + linalool.	got7fsn_ti												EC:3.2.1.149|MetaCyc:RXN-13701		molecular_function											owl:Class	
GO:0072696	biolink:NamedThing	positive regulation of DNA recombination at telomere	Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere.	got7fsn_ti	positive regulation of telomeric recombination|upregulation of telomeric recombination at telomere|activation of telomeric recombination at telomere|up-regulation of telomeric recombination at telomere|up regulation of telomeric recombination at telomere						mah	2012-04-03T11:28:19Z						biological_process											owl:Class	
GO:0072695	biolink:NamedThing	regulation of DNA recombination at telomere	Any process that modulates the frequency, rate or extent of DNA recombination within the telomere.	got7fsn_ti	regulation of telomeric recombination						mah	2012-04-03T10:31:50Z						biological_process											owl:Class	
GO:1900573	biolink:NamedThing	emodin metabolic process	The chemical reactions and pathways involving emodin.	got7fsn_ti	emodin metabolism						di	2012-05-15T06:41:44Z						biological_process											owl:Class	
GO:0006769	biolink:NamedThing	nicotinamide metabolic process	The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.	got7fsn_ti	niacin metabolic process|vitamin B3 metabolism|nicotinamide metabolism|niacin metabolism|vitamin B3 metabolic process											MetaCyc:PWY-5083		biological_process											owl:Class	
GO:0075201	biolink:NamedThing	penetration hypha formation	The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	formation of symbiont penetration hypha for entry into host|symbiont penetration hypha formation for entry into host	https://github.com/geneontology/go-ontology/issues/18557			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0036063	biolink:NamedThing	acroblast	A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle.	got7fsn_ti	spermatid acroblast				See also the fly_anatomy.ontology term 'acroblast ; FBbt:00004947'.		bf	2011-12-14T02:29:05Z						cellular_component											owl:Class	
GO:0047653	biolink:NamedThing	allantoin racemase activity	Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin.	got7fsn_ti												EC:5.1.99.3|MetaCyc:ALLANTOIN-RACEMASE-RXN|KEGG_REACTION:R03925|RHEA:10804		molecular_function											owl:Class	
GO:0006139	biolink:NamedThing	nucleobase-containing compound metabolic process	Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.	got7fsn_ti	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|nucleobase, nucleoside and nucleotide metabolic process|cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism|nucleobase, nucleoside, nucleotide and nucleic acid metabolism										GO:0055134			biological_process											owl:Class	
GO:0042270	biolink:NamedThing	protection from natural killer cell mediated cytotoxicity	The process of protecting a cell from natural killer cell mediated cytotoxicity.	got7fsn_ti	protection from NK cell mediated cytolysis|protection from natural killer cell mediated cell killing|protection from NK cell mediated cell death|protection from natural killer cell mediated cell death|protection from NK cell mediated cytotoxicity|protection from NK cell mediated cell killing|protection from natural killer cell mediated cytolysis													biological_process											owl:Class	
GO:0045953	biolink:NamedThing	negative regulation of natural killer cell mediated cytotoxicity	Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.	got7fsn_ti	downregulation of natural killer cell mediated cytotoxicity|down regulation of natural killer cell mediated cytotoxicity|inhibition of natural killer cell mediated cytotoxicity|negative regulation of NK cell mediated cell killing|negative regulation of natural killer cell mediated cytolysis|negative regulation of natural killer cell mediated cell death|negative regulation of natural killer cell mediated cell killing|negative regulation of NK cell mediated cytolysis|down-regulation of natural killer cell mediated cytotoxicity|negative regulation of NK cell mediated cytotoxicity|negative regulation of NK cell mediated cell death													biological_process											owl:Class	
GO:0047817	biolink:NamedThing	D-arginase activity	Catalysis of the reaction: D-arginine + H(2)O = D-ornithine + urea.	got7fsn_ti	D-arginine amidinohydrolase activity											EC:3.5.3.10|RHEA:12901|MetaCyc:D-ARGINASE-RXN|KEGG_REACTION:R02458		molecular_function											owl:Class	
GO:0075037	biolink:NamedThing	positive regulation of appressorium maturation	Any process that activates or increases the frequency, rate or extent of symbiont appressorium maturation.	got7fsn_ti	positive regulation of appressorium maturation on or near host|positive regulation maturation of appressorium on or near host													biological_process											owl:Class	
GO:0019095	biolink:NamedThing	pole plasm mitochondrial rRNA localization	Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte pole plasm mitochondrial rRNA localization|establishment and maintenance of mitochondrial rRNA localization in pole plasm|pole plasm mitochondrial rRNA localisation										GO:0048117			biological_process											owl:Class	
GO:0036190	biolink:NamedThing	indole-2-monooxygenase activity	Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O.	got7fsn_ti							bf	2012-04-19T11:24:48Z				RHEA:31899|EC:1.14.14.153|KEGG_REACTION:R07403		molecular_function											owl:Class	
GO:0046522	biolink:NamedThing	S-methyl-5-thioribose kinase activity	Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H(+).	got7fsn_ti	ATP:S-methyl-5-thio-D-ribose 1-phosphotransferase activity|ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase activity|5-methylthioribose kinase (phosphorylating)|MTR kinase activity|5-methylthioribose kinase activity|methylthioribose kinase activity											EC:2.7.1.100|KEGG_REACTION:R04143|MetaCyc:5-METHYLTHIORIBOSE-KINASE-RXN|RHEA:22312		molecular_function											owl:Class	
GO:0046103	biolink:NamedThing	inosine biosynthetic process	The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.	got7fsn_ti	inosine anabolism|inosine formation|inosine synthesis|inosine biosynthesis													biological_process											owl:Class	
GO:0033307	biolink:NamedThing	phytol salvage	A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis.	got7fsn_ti	phytol salvage pathway											MetaCyc:PWY-5107		biological_process											owl:Class	
GO:0033520	biolink:NamedThing	phytol biosynthetic process	The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.	got7fsn_ti	phytol formation|phytol anabolism|phytol biosynthesis|phytol synthesis													biological_process											owl:Class	
GO:1900574	biolink:NamedThing	emodin catabolic process	The chemical reactions and pathways resulting in the breakdown of emodin.	got7fsn_ti	emodin breakdown|emodin catabolism|emodin degradation						di	2012-05-15T06:42:06Z						biological_process											owl:Class	
GO:0031895	biolink:NamedThing	V1B vasopressin receptor binding	Binding to a V1B vasopressin receptor.	got7fsn_ti	V1B vasopressin receptor ligand													molecular_function											owl:Class	
GO:0004997	biolink:NamedThing	thyrotropin-releasing hormone receptor activity	Combining with thyrotropin-releasing hormone to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0039006	biolink:NamedThing	pronephric nephron tubule formation	The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros.	got7fsn_ti	pronephros tubule formation|pronephric tubule formation						bf	2010-07-02T09:37:27Z						biological_process											owl:Class	
GO:0000469	biolink:NamedThing	cleavage involved in rRNA processing	Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.	got7fsn_ti	cleavage during rRNA processing													biological_process											owl:Class	
GO:0004014	biolink:NamedThing	adenosylmethionine decarboxylase activity	Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2).	got7fsn_ti	S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium-salt-forming]|S-adenosylmethionine decarboxylase activity|adenosyl methionine decarboxylase activity|S-adenosyl-L-methionine carboxy-lyase activity|S-adenosyl-L-methionine decarboxylase activity											RHEA:15981|MetaCyc:SAMDECARB-RXN|EC:4.1.1.50|Reactome:R-HSA-351222|KEGG_REACTION:R00178		molecular_function											owl:Class	
GO:0030594	biolink:NamedThing	neurotransmitter receptor activity	Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity.	got7fsn_ti					A strict definition of neurotransmitter receptor activity would limit its use to receptor activity at the postsynaptic membrane as part of synaptic transmission, but we recognize that usage is often much broader than this. For the strict use case, please see 'postsynaptic neurotransmitter receptor activity'									molecular_function											owl:Class	
GO:0120286	biolink:NamedThing	tryptophan sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of tryptophan.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20181					krc	2020-11-18T01:25:01Z						molecular_function											owl:Class	
GO:0120284	biolink:NamedThing	tryptophan binding	Binding to 2-amino-3-(1H-indol-3-yl)propanoic acid.	got7fsn_ti	Trp binding	https://github.com/geneontology/go-ontology/issues/20181					krc	2020-11-18T01:04:19Z						molecular_function											owl:Class	
GO:0034363	biolink:NamedThing	intermediate-density lipoprotein particle	A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).	got7fsn_ti	IDL complex|IDL particle|intermediate-density lipoprotein complex													cellular_component											owl:Class	
GO:0050125	biolink:NamedThing	N-benzyloxycarbonylglycine hydrolase activity	Catalysis of the reaction: N-benzyloxycarbonylglycine + H(2)O + H(+) = benzyl alcohol + CO(2) + glycine.	got7fsn_ti	benzyloxycarbonylglycine hydrolase activity|nalpha-carbobenzoxyamino acid amidohydrolase activity|N-benzyloxycarbonylglycine urethanehydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase I|nalpha-benzyloxycarbonyl amino acid urethane hydrolase activity											EC:3.5.1.58|RHEA:20900|KEGG_REACTION:R02551|MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN		molecular_function											owl:Class	
GO:0050220	biolink:NamedThing	prostaglandin-E synthase activity	Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2).	got7fsn_ti	PGH-PGE isomerase activity|PGE2 isomerase activity|endoperoxide isomerase activity|prostaglandin-H2 E-isomerase activity|Prostaglandin-H(2) E-isomerase activity|prostaglandin H-E isomerase activity|prostaglandin R-prostaglandin E isomerase activity|prostaglandin endoperoxide E isomerase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|PGE isomerase activity|prostaglandin endoperoxide E2 isomerase activity											EC:5.3.99.3|MetaCyc:PROSTAGLANDIN-E-SYNTHASE-RXN|Reactome:R-HSA-265295|RHEA:12893|Reactome:R-HSA-2161660|KEGG_REACTION:R02265		molecular_function											owl:Class	
GO:0035743	biolink:NamedThing	CD4-positive, alpha-beta T cell cytokine production	Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-03-17T02:21:51Z						biological_process											owl:Class	
GO:0002369	biolink:NamedThing	T cell cytokine production	Any process that contributes to cytokine production by a T cell.	got7fsn_ti	T-cell cytokine production|T-lymphocyte cytokine production|T lymphocyte cytokine production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0035026	biolink:NamedThing	leading edge cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet.	got7fsn_ti														biological_process											owl:Class	
GO:0032402	biolink:NamedThing	melanosome transport	The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0042197	biolink:NamedThing	halogenated hydrocarbon metabolic process	The chemical reactions and pathways involving halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. Halogens include fluorine, chlorine, bromine and iodine.	got7fsn_ti	halogenated hydrocarbon metabolism													biological_process											owl:Class	
GO:0102392	biolink:NamedThing	decanoate-[HmqF protein] ligase activity	Catalysis of the reaction: decanoate + ATP(4-) + an HmqF protein <=> AMP(2-) + diphosphoric acid + a decanoyl-HmqF protein.	got7fsn_ti												MetaCyc:RXN-13623		molecular_function											owl:Class	
GO:0102052	biolink:NamedThing	indole-3-acetyl-proline synthetase activity	Catalysis of the reaction: indole-3-acetate + L-proline + ATP(4-) <=> H+ + indole-3-acetyl-proline + AMP(2-) + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10434		molecular_function											owl:Class	
GO:0098678	biolink:NamedThing	viral tropism switching	A process by which the range of hosts which a virus can bind and infect is changed.  Examples include phages that switch between types of fibers via the action of a virally encoded invertase.	got7fsn_ti							dos	2017-01-19T13:05:51Z				VZ:4498		biological_process											owl:Class	
GO:0072227	biolink:NamedThing	metanephric macula densa development	The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.	got7fsn_ti							mah	2010-03-18T03:37:26Z						biological_process											owl:Class	
GO:0010342	biolink:NamedThing	endosperm cellularization	The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization.	got7fsn_ti	cellularization of endosperm													biological_process											owl:Class	
GO:0007349	biolink:NamedThing	cellularization	The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.	got7fsn_ti											GO:0009796			biological_process											owl:Class	
GO:1990488	biolink:NamedThing	anaerobic cellulose catabolic process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen.	got7fsn_ti	anaerobic cellulose degradation						tt	2014-09-20T17:43:59Z						biological_process											owl:Class	
GO:0030245	biolink:NamedThing	cellulose catabolic process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.	got7fsn_ti	cellulose catabolism|cellulose breakdown|cellulose degradation										GO:0016179			biological_process											owl:Class	
GO:0102765	biolink:NamedThing	UDP-D-apiose synthase activity	Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = UDP-alpha-D-apiose + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-7770		molecular_function											owl:Class	
GO:0002536	biolink:NamedThing	respiratory burst involved in inflammatory response	A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.	got7fsn_ti	production of reactive oxygen species during acute inflammatory response|respiratory burst involved in acute inflammatory response|oxidative burst during acute inflammatory response													biological_process											owl:Class	
GO:0021728	biolink:NamedThing	inferior reticular formation development	The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:1990210	biolink:NamedThing	positive regulation by symbiont of indole acetic acid levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of auxin levels in host|positive regulation by symbiont of IAA levels in host						ml	2013-10-09T18:54:11Z						biological_process											owl:Class	
GO:0047754	biolink:NamedThing	choline sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H(+).	got7fsn_ti	choline sulphokinase activity|choline sulphotransferase activity|3'-phosphoadenylyl-sulfate:choline sulfotransferase activity											EC:2.8.2.6|MetaCyc:CHOLINE-SULFOTRANSFERASE-RXN|KEGG_REACTION:R01027|RHEA:21984		molecular_function											owl:Class	
GO:1900683	biolink:NamedThing	regulation of fumonisin biosynthetic process	Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process.	got7fsn_ti	regulation of fumonisin anabolism|regulation of fumonisin biosynthesis|regulation of fumonisin synthesis|regulation of fumonisin formation						di	2012-05-22T04:29:38Z						biological_process											owl:Class	
GO:0051355	biolink:NamedThing	proprioception involved in equilibrioception	The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.	got7fsn_ti	proprioception during equilibrioception|equilibrioception by proprioception|perception of orientation with respect to gravity by proprioception													biological_process											owl:Class	
GO:0034801	biolink:NamedThing	2,4-dinitrocyclohexanone hydrolase activity	Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate.	got7fsn_ti												UM-BBD_reactionID:r1069		molecular_function											owl:Class	
GO:0042768	biolink:NamedThing	ecdysteroid 2-hydroxylase activity	Catalysis of the hydroxylation of an ecdysteroid at carbon position 2.	got7fsn_ti					Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2-deoxyecdysone to ecdysone. It can also catalyze the conversion of 2,22-dideoxyecdysone (ketotriol) to 22-deoxyecdysone.									molecular_function											owl:Class	
GO:0034073	biolink:NamedThing	tetrahymanol cyclase activity	Catalysis of the reaction: squalene = tetrahymanol.	got7fsn_ti														molecular_function											owl:Class	
GO:0034072	biolink:NamedThing	squalene cyclase activity	Catalysis of the reaction: squalene = triterpene.	got7fsn_ti														molecular_function											owl:Class	
GO:0016762	biolink:NamedThing	xyloglucan:xyloglucosyl transferase activity	Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.	got7fsn_ti	endo-xyloglucan transferase activity|endoxyloglucan transferase activity|xyloglucan endotransglucosylase activity|xyloglucan:xyloglucan xyloglucanotransferase activity										GO:0080039	MetaCyc:2.4.1.207-RXN|EC:2.4.1.207		molecular_function											owl:Class	
GO:0010284	biolink:NamedThing	lariciresinol reductase activity	Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+.	got7fsn_ti												MetaCyc:RXN-8684|MetaCyc:RXN-8679		molecular_function											owl:Class	
GO:0140486	biolink:NamedThing	zinc ion sequestering activity	The selective interaction of a protein with a zinc ion to prevent it from interacting with sensitive components of a biological system.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19700					pg	2020-06-29T09:21:42Z						molecular_function											owl:Class	
GO:0052085	biolink:NamedThing	suppression by symbiont of host T-cell mediated immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition by symbiont of host T-cell mediated immune response|down-regulation by symbiont of host T-cell mediated immune response|downregulation by symbiont of host T-cell mediated immune response|down regulation by symbiont of host T-cell mediated immune response|negative regulation by symbiont of host T-cell mediated immune response|negative regulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction										GO:0052280			biological_process											owl:Class	
GO:0033075	biolink:NamedThing	isoquinoline alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.	got7fsn_ti	isoquinoline alkaloid biosynthesis|isoquinoline alkaloid synthesis|ipecac alkaloid biosynthesis|isoquinoline alkaloid anabolism|isoquinoline alkaloid formation													biological_process											owl:Class	
GO:0003951	biolink:NamedThing	NAD+ kinase activity	Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+).	got7fsn_ti	NADK|nicotinamide adenine dinucleotide kinase activity|nicotinamide adenine dinucleotide kinase (phosphorylating)|NAD kinase activity|ATP:NAD+ 2'-phosphotransferase activity|DPN kinase activity											EC:2.7.1.23|MetaCyc:NAD-KIN-RXN|Reactome:R-HSA-8955030|KEGG_REACTION:R00104|RHEA:18629|Reactome:R-HSA-197198		molecular_function											owl:Class	
GO:0102529	biolink:NamedThing	apigenin 7-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + apigenin-7-olate <=> S-adenosyl-L-homocysteine  + genkwanin.	got7fsn_ti												MetaCyc:RXN-14661		molecular_function											owl:Class	
GO:0034942	biolink:NamedThing	cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity	Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.	got7fsn_ti												UM-BBD_reactionID:r0988		molecular_function											owl:Class	
GO:0004173	biolink:NamedThing	ecdysone O-acyltransferase activity	Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate.	got7fsn_ti	palmitoyl-CoA:ecdysone palmitoyltransferase activity|fatty acyl-CoA:ecdysone acyltransferase activity|acyl-CoA:ecdysone acyltransferase activity											EC:2.3.1.139|RHEA:15217|KEGG_REACTION:R02375|MetaCyc:ECDYSONE-O-ACYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0034206	biolink:NamedThing	enhanceosome	A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation.	got7fsn_ti												Wikipedia:Enhanceosome		cellular_component											owl:Class	
GO:0050071	biolink:NamedThing	lysyltransferase activity	Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol.	got7fsn_ti	L-lysyl-tRNA:phosphatidylglycerol O3-lysyltransferase activity|L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase activity											EC:2.3.2.3|MetaCyc:LYSYLTRANSFERASE-RXN|RHEA:10668		molecular_function											owl:Class	
GO:0036438	biolink:NamedThing	maintenance of lens transparency	A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina.	got7fsn_ti	maintenance of ocular lens transparency|preservation of lens transparency						bf	2013-09-23T13:51:09Z						biological_process											owl:Class	
GO:0036499	biolink:NamedThing	PERK-mediated unfolded protein response	A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity.	got7fsn_ti	eukaryotic translation initiation factor 2-alpha kinase 3-mediated unfolded protein response|PERK signal transduction pathway|endoplasmic reticulum unfolded protein response; PERK signaling|UPR signaling by PERK stress sensor|EIF2AK3-mediated unfolded protein response|PERK branch of UPR|PERK signaling in response to endoplasmic reticulum stress|PKR-like ER kinase signal transduction						bf	2015-02-05T13:17:43Z						biological_process											owl:Class	
GO:0008997	biolink:NamedThing	ribonuclease R activity	Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides.	got7fsn_ti												EC:3.1.11.-		molecular_function											owl:Class	
GO:0060418	biolink:NamedThing	yolk plasma	Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.	got7fsn_ti														cellular_component											owl:Class	
GO:0097225	biolink:NamedThing	sperm midpiece	The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.	got7fsn_ti							pr	2012-01-25T01:23:41Z						cellular_component											owl:Class	
GO:0097701	biolink:NamedThing	response to pulsatile fluid shear stress	Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects.	got7fsn_ti							pr	2016-01-27T14:13:31Z						biological_process											owl:Class	
GO:0021634	biolink:NamedThing	optic nerve formation	The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	got7fsn_ti	CN II biosynthesis|CN II formation													biological_process											owl:Class	
GO:1900569	biolink:NamedThing	chanoclavine-I aldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde.	got7fsn_ti	chanoclavine-I aldehyde anabolism|chanoclavine-I aldehyde formation|chanoclavine-I aldehyde synthesis|chanoclavine-I aldehyde biosynthesis						di	2012-05-15T06:31:28Z						biological_process											owl:Class	
GO:0034946	biolink:NamedThing	3-isopropylbut-3-enoyl-CoA thioesterase activity	Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH.	got7fsn_ti												UM-BBD_reactionID:r0994		molecular_function											owl:Class	
GO:0031845	biolink:NamedThing	type 5 neuropeptide Y receptor binding	Binding to a type 5 neuropeptide Y receptor.	got7fsn_ti	type 5 neuropeptide Y receptor ligand													molecular_function											owl:Class	
GO:0102201	biolink:NamedThing	(+)-2-epi-prezizaene synthase activity	Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-12117		molecular_function											owl:Class	
GO:0044354	biolink:NamedThing	macropinosome	A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.	got7fsn_ti							jl	2011-08-11T10:51:42Z						cellular_component											owl:Class	
GO:0106013	biolink:NamedThing	negative regulation of protein localization to cell cortex of cell tip	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip.	got7fsn_ti							hjd	2017-04-28T13:45:38Z						biological_process											owl:Class	
GO:0002105	biolink:NamedThing	endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0016200	biolink:NamedThing	synaptic target attraction	The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.	got7fsn_ti														biological_process											owl:Class	
GO:0071186	biolink:NamedThing	protocadherin-alpha-v4-protocadherin-gamma-b2 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti	Pcdhga1-Pcdhgb2 complex						mah	2009-11-23T04:21:33Z						cellular_component											owl:Class	
GO:0097363	biolink:NamedThing	protein O-GlcNAc transferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.	got7fsn_ti	O-GlcNAc transferase|UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase|O-linked N-acetylglucosaminyltransferase|OGTase						pr	2012-07-24T01:46:51Z				EC:2.4.1.255|Reactome:R-HSA-9687828		molecular_function											owl:Class	
GO:0050306	biolink:NamedThing	sucrose 1F-fructosyltransferase activity	Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose.	got7fsn_ti	sucrose:sucrose 1'-beta-D-fructosyltransferase activity|sucrose:sucrose 1(F)-beta-D-fructosyltransferase activity|sucrose-sucrose 1-fructosyltransferase activity|SST activity|sucrose:sucrose 1-fructosyltransferase activity|sucrose:sucrose 1F-beta-D-fructosyltransferase activity|sucrose 1(F)-fructosyltransferase activity|sucrose:sucrose fructosyltransferase activity											EC:2.4.1.99|RHEA:23312|MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0044647	biolink:NamedThing	host-symbiont bicellular tight junction	An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane.	got7fsn_ti	host-parasite tight junction|host-pathogen tight junction						jl	2012-07-11T12:56:18Z						cellular_component											owl:Class	
GO:0005923	biolink:NamedThing	bicellular tight junction	An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.	got7fsn_ti	zonula occludens											Wikipedia:Tight_junction|NIF_Subcellular:sao1939999134		cellular_component											owl:Class	
GO:0140393	biolink:NamedThing	norsolorinic acid ketoreductase activity	Catalysis of the reaction: (1'S)-averantin + NADP(+) <=> norsolorinic acid + NADPH.	got7fsn_ti							pg	2019-11-28T14:38:12Z				RHEA:35447|EC:1.1.1.349|KEGG_REACTION:R10309|MetaCyc:RXN-9480		molecular_function											owl:Class	
GO:0045703	biolink:NamedThing	ketoreductase activity	Catalysis of the reduction of a ketone group to form the corresponding alcohol.	got7fsn_ti														molecular_function											owl:Class	
GO:0072228	biolink:NamedThing	metanephric prebend segment development	The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.	got7fsn_ti							mah	2010-03-18T03:37:46Z						biological_process											owl:Class	
GO:0072066	biolink:NamedThing	prebend segment development	The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.	got7fsn_ti							mah	2010-01-25T04:14:02Z						biological_process											owl:Class	
GO:0031014	biolink:NamedThing	troponin T binding	Binding to troponin T, the tropomyosin-binding subunit of the troponin complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0015732	biolink:NamedThing	prostaglandin transport	The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0016937	biolink:NamedThing	short-branched-chain-acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue.	got7fsn_ti												EC:1.3.99.-		molecular_function											owl:Class	
GO:0034269	biolink:NamedThing	discadenine catabolic process	The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.	got7fsn_ti	discadenine breakdown|discadenine degradation|discadenine catabolism													biological_process											owl:Class	
GO:0061185	biolink:NamedThing	negative regulation of dermatome development	Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.	got7fsn_ti							dph	2010-07-14T08:43:08Z						biological_process											owl:Class	
GO:0060969	biolink:NamedThing	negative regulation of gene silencing	Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.	got7fsn_ti							dph	2009-10-05T03:26:19Z						biological_process											owl:Class	
GO:0010628	biolink:NamedThing	positive regulation of gene expression	Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	got7fsn_ti														biological_process											owl:Class	
GO:0062243	biolink:NamedThing	double membrane vesicle viral factory outer membrane	The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.	got7fsn_ti	outer membrane of double membrane vesicle viral factory						dph	2020-04-20T20:47:40Z						cellular_component											owl:Class	
GO:0062242	biolink:NamedThing	double membrane vesicle viral factory membrane	One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.	got7fsn_ti	membrane of double membrane vesicle viral factory						dph	2020-04-20T20:42:28Z						cellular_component											owl:Class	
GO:0035500	biolink:NamedThing	MH2 domain binding	Binding to a MH2 (MAD homology 2) protein domain. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.	got7fsn_ti	MAD homology 2 domain binding						bf	2010-04-29T03:14:32Z						molecular_function											owl:Class	
GO:0009883	biolink:NamedThing	red or far-red light photoreceptor activity	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.	got7fsn_ti	red/far-red light photoreceptor activity													molecular_function											owl:Class	
GO:0009881	biolink:NamedThing	photoreceptor activity	The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.	got7fsn_ti	violet-sensitive opsin|opsin|long-wave-sensitive opsin|short-wave-sensitive opsin|green-sensitive opsin|UV-sensitive opsin|blue-sensitive opsin|red-sensitive opsin													molecular_function											owl:Class	
GO:0047571	biolink:NamedThing	3-oxosteroid 1-dehydrogenase activity	Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor.	got7fsn_ti	delta1-dehydrogenase activity|3-oxosteroid:acceptor delta1-oxidoreductase activity|3-ketosteroid-1-en-dehydrogenase activity|3-oxosteroid:(2,6-dichlorphenolindophenol) delta1-oxidoreductase activity|1-ene-dehydrogenase activity|3-ketosteroid-delta1-dehydrogenase activity|4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase activity|delta1-steroid reductase activity|3-oxosteroid delta1-dehydrogenase activity|3-oxosteroid:(acceptor) delta1-oxidoreductase activity											UM-BBD_enzymeID:e0712|MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN|RHEA:13329|EC:1.3.99.4		molecular_function											owl:Class	
GO:0002338	biolink:NamedThing	B-1b B cell differentiation	The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.	got7fsn_ti	B-1b B-cell differentiation|B-1b B lymphocyte differentiation|B-1b B cell development|B-1b B-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0035580	biolink:NamedThing	specific granule lumen	The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.	got7fsn_ti	secondary granule lumen						bf	2010-10-05T01:33:53Z						cellular_component											owl:Class	
GO:0003785	biolink:NamedThing	actin monomer binding	Binding to monomeric actin, also known as G-actin.	got7fsn_ti	G actin binding													molecular_function											owl:Class	
GO:0030057	biolink:NamedThing	desmosome	A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.	got7fsn_ti	spot desmosome|macula adherens											Wikipedia:Desmosome		cellular_component											owl:Class	
GO:0038105	biolink:NamedThing	sequestering of TGFbeta from receptor via TGFbeta binding	Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor.	got7fsn_ti	extracellular sequestering of TGFbeta|extracellular sequestering of transforming growth factor-beta				This term is for annotation of gene products that bind to TGFbeta. For gene products that tether the TGFbeta-containing latency complex to the extracellular matrix, but do not necessarily bind TGF-beta directly, consider instead annotating to 'sequestering of TGFbeta in extracellular matrix ; GO:0035583'.		bf	2012-02-22T11:35:58Z						biological_process											owl:Class	
GO:0035581	biolink:NamedThing	sequestering of extracellular ligand from receptor	The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.	got7fsn_ti	extracellular sequestering of receptor ligand|negative regulation of protein bioavailability				Preventing a ligand from binding to its cell surface receptor be achieved by binding to the ligand directly, or by binding to members of a ligand-containing complex.		bf	2010-10-12T03:12:11Z						biological_process											owl:Class	
GO:0090443	biolink:NamedThing	FAR/SIN/STRIPAK complex	A conserved protein phosphatase type 2A complex which contains a protein phosphatase type 2A, a protein phosphatase regulatory subunit, a striatin, an FHA domain protein and other subunits (at least six proteins). In fission yeast this complex negatively regulate the septation initiation network at the spindle pole body.	got7fsn_ti	FAR complex|STRIPAK signalling complex|SIP complex|striatin interacting phosphatase and kinase complex						tb	2012-08-23T14:20:39Z						cellular_component											owl:Class	
GO:0089710	biolink:NamedThing	endocytic targeting sequence binding	Binding to a endocytic signal sequence, a specific peptide sequence, of 4-6 amino acids with an essential tyrosine (Y), found on cytoplasmic tails of some cell surface membrane proteins, which directs internalization by clathrin-coated pits.	got7fsn_ti														molecular_function											owl:Class	
GO:0102085	biolink:NamedThing	N-(4-aminobenzoyl)-L-glutamate synthetase activity	Catalysis of the reaction: 4-aminobenzoate + L-glutamate + ATP <=> H+ + p-aminobenzoyl glutamate + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10884		molecular_function											owl:Class	
GO:0070865	biolink:NamedThing	investment cone	A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.	got7fsn_ti	F-actin cone						mah	2009-08-19T01:29:33Z						cellular_component											owl:Class	
GO:0004925	biolink:NamedThing	prolactin receptor activity	Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0047293	biolink:NamedThing	4-hydroxybenzoate nonaprenyltransferase activity	Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate.	got7fsn_ti	solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase activity|nonaprenyl-4-hydroxybenzoate transferase activity|p-hydroxybenzoic acid-polyprenyl transferase activity|4-hydroxybenzoate transferase activity|p-hydroxybenzoate polyprenyltransferase activity|p-hydroxybenzoate dimethylallyltransferase activity|p-hydroxybenzoic-polyprenyl transferase activity											MetaCyc:2.5.1.39-RXN|RHEA:17709|EC:2.5.1.39		molecular_function											owl:Class	
GO:0106126	biolink:NamedThing	reservosome membrane	The lipid bilayer surrounding a reservosome.	got7fsn_ti							hjd	2018-05-03T18:01:26Z						cellular_component											owl:Class	
GO:0047304	biolink:NamedThing	2-aminoethylphosphonate-pyruvate transaminase activity	Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde.	got7fsn_ti	(2-aminoethyl)phosphonate:pyruvate aminotransferase activity|(2-aminoethyl)phosphonate aminotransferase activity|2-aminoethylphosphonate aminotransferase activity|(2-aminoethyl)phosphonic acid aminotransferase activity|2-aminoethylphosphonate-pyruvate aminotransferase activity|(2-aminoethyl)phosphonate--pyruvate aminotransferase activity|(2-aminoethyl)phosphonate transaminase activity|2-aminoethylphosphonate--pyruvate aminotransferase activity											MetaCyc:2.6.1.37-RXN|RHEA:17021|KEGG_REACTION:R04152|EC:2.6.1.37		molecular_function											owl:Class	
GO:0047728	biolink:NamedThing	carnitine 3-dehydrogenase activity	Catalysis of the reaction: carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH.	got7fsn_ti	carnitine:NAD+ 3-oxidoreductase activity											EC:1.1.1.108|MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN|RHEA:19265|KEGG_REACTION:R02395		molecular_function											owl:Class	
GO:0070083	biolink:NamedThing	clathrin-sculpted monoamine transport vesicle membrane	The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle.	got7fsn_ti	clathrin sculpted monoamine transport vesicle membrane|clathrin sculpted monoamine constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0090705	biolink:NamedThing	trichome papilla	A plant cell papilla that is part of a trichome cell.	got7fsn_ti					Part of trichome cell (PO:0008030).		tb	2016-09-26T12:49:36Z						cellular_component											owl:Class	
GO:0007316	biolink:NamedThing	pole plasm RNA localization	Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	got7fsn_ti	establishment and maintenance of pole plasm RNA localization|pole plasm RNA localisation|oocyte pole plasm RNA localization										GO:0048116			biological_process											owl:Class	
GO:0042609	biolink:NamedThing	CD4 receptor binding	Binding to a CD4, a receptor found on the surface of T cells, monocytes and macrophages.	got7fsn_ti														molecular_function											owl:Class	
GO:0019715	biolink:NamedThing	peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid	The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).	got7fsn_ti					See also the molecular function term 'peptide-aspartate beta-dioxygenase activity ; GO:0004597'.							RESID:AA0027		biological_process											owl:Class	
GO:0089715	biolink:NamedThing	tRNA m6t6A37 methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine.	got7fsn_ti					This activity is distinct from 'tRNA (adenine-N6-)-methyltransferase activity' (GO:0016430) in that it requires the presence of a threonylcarbamoyl modification.							MetaCyc:RXN0-7114		molecular_function											owl:Class	
GO:0061157	biolink:NamedThing	mRNA destabilization	Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.	got7fsn_ti							dph	2010-06-22T08:42:10Z						biological_process											owl:Class	
GO:0050779	biolink:NamedThing	RNA destabilization	Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.	got7fsn_ti														biological_process											owl:Class	
GO:0097523	biolink:NamedThing	transcription ternary complex	A protein-DNA-RNA complex composed of RNA polymerase, template DNA, and an RNA transcript.	got7fsn_ti	transcription protein-DNA-RNA complex						pr	2013-10-18T11:29:57Z						cellular_component											owl:Class	
GO:0061736	biolink:NamedThing	engulfment of target by autophagosome	The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.	got7fsn_ti							dph	2015-09-14T14:10:24Z						biological_process											owl:Class	
GO:0010255	biolink:NamedThing	glucose mediated signaling pathway	The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes.	got7fsn_ti	glucose mediated signalling													biological_process											owl:Class	
GO:1990538	biolink:NamedThing	xylan O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan.	got7fsn_ti							tb	2014-11-18T20:02:51Z						molecular_function											owl:Class	
GO:0060449	biolink:NamedThing	bud elongation involved in lung branching	The process in which a bud in the lung grows out from the point where it is formed.	got7fsn_ti														biological_process											owl:Class	
GO:0047540	biolink:NamedThing	2-enoate reductase activity	Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+.	got7fsn_ti	butanoate:NAD+ delta2-oxidoreductase activity|enoate reductase activity											EC:1.3.1.31|MetaCyc:2-ENOATE-REDUCTASE-RXN|RHEA:10200		molecular_function											owl:Class	
GO:0016149	biolink:NamedThing	translation release factor activity, codon specific	A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.	got7fsn_ti														molecular_function											owl:Class	
GO:0035197	biolink:NamedThing	siRNA binding	Binding to a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.	got7fsn_ti	small interfering RNA binding													molecular_function											owl:Class	
GO:0061980	biolink:NamedThing	regulatory RNA binding	Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme.	got7fsn_ti							dph	2018-02-13T21:46:08Z						molecular_function											owl:Class	
GO:0052838	biolink:NamedThing	thiazole metabolic process	The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.	got7fsn_ti	thiazole metabolism						ai	2011-11-29T03:35:50Z						biological_process											owl:Class	
GO:0102490	biolink:NamedThing	8-oxo-dGTP phosphohydrolase activity	Catalysis of the reaction: 8-oxo-dGTP + 2 H2O <=> 8-oxo-dGMP + 2 hydrogenphosphate + 2 H+.	got7fsn_ti												EC:3.6.1.5|MetaCyc:RXN-14205		molecular_function											owl:Class	
GO:0050480	biolink:NamedThing	imidazolonepropionase activity	Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H(2)O = N-formimidoyl-L-glutamate + H(+).	got7fsn_ti	3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate amidohydrolase activity|imidazolone-5-propionate hydrolase activity|4(5)-imidazolone-5(4)-propionic acid hydrolase activity|imidazolone propionic acid hydrolase activity											MetaCyc:IMIDAZOLONEPROPIONASE-RXN|RHEA:23660|KEGG_REACTION:R02288|EC:3.5.2.7		molecular_function											owl:Class	
GO:0047263	biolink:NamedThing	N-acylsphingosine galactosyltransferase activity	Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP.	got7fsn_ti	UDP-galactose:N-acylsphingosine D-galactosyltransferase activity|UDPgalactose:N-acylsphingosine D-galactosyltransferase activity|uridine diphosphogalactose-acylsphingosine galactosyltransferase activity|UDP galactose-N-acylsphingosine galactosyltransferase activity											Reactome:R-HSA-6785933|RHEA:13093|MetaCyc:2.4.1.47-RXN|EC:2.4.1.47		molecular_function											owl:Class	
GO:0102182	biolink:NamedThing	4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity	Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD <=> avenastenone + NADH + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-11938		molecular_function											owl:Class	
GO:0043224	biolink:NamedThing	nuclear SCF ubiquitin ligase complex	A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).	got7fsn_ti	nuclear Skp1/Cul1/F-box protein complex|nuclear SCF complex|nuclear cullin complex													cellular_component											owl:Class	
GO:0010448	biolink:NamedThing	vegetative meristem growth	The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia.	got7fsn_ti														biological_process											owl:Class	
GO:0047928	biolink:NamedThing	gibberellin beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.	got7fsn_ti	uridine diphosphoglucose-gibberellate 7-glucosyltransferase activity|UDP-glucose:gibberellin 2-O-beta-D-glucosyltransferase activity|UDPglucose:gibberellin 2-O-beta-D-glucosyltransferase activity|gibberellin b-glucosyltransferase activity|uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase activity											RHEA:20025|MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.176		molecular_function											owl:Class	
GO:0010305	biolink:NamedThing	leaf vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the leaf of vascular plants.	got7fsn_ti														biological_process											owl:Class	
GO:0015395	biolink:NamedThing	nucleoside transmembrane transporter activity, down a concentration gradient	Enables the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient.	got7fsn_ti	equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-sensitive activity|equilibrative nucleoside transporter activity|equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-insensitive activity										GO:0015396|GO:0015397			molecular_function											owl:Class	
GO:0010790	biolink:NamedThing	meiotic sister chromatid cohesion involved in meiosis II	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.	got7fsn_ti														biological_process											owl:Class	
GO:0120324	biolink:NamedThing	procyclogenesis	The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei.	got7fsn_ti		https://github.com/geneontology/go-ontology/pull/21924					krc	2021-08-03T19:53:17Z						biological_process											owl:Class	
GO:0007250	biolink:NamedThing	activation of NF-kappaB-inducing kinase activity	The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.	got7fsn_ti	positive regulation of NF-kappaB-inducing kinase activity|activation of NIK activity													biological_process											owl:Class	
GO:0007111	biolink:NamedThing	meiosis II cytokinesis	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.	got7fsn_ti	cytokinesis after meiosis II													biological_process											owl:Class	
GO:0003917	biolink:NamedThing	DNA topoisomerase type I (single strand cut, ATP-independent) activity	Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.	got7fsn_ti	type I topoisomerase activity|omega-protein activity|untwisting enzyme activity|topoisomerase|relaxing enzyme activity|nicking-closing enzyme activity|deoxyribonucleate topoisomerase|type I DNA topoisomerase activity|DNA topoisomerase I activity|swivelase activity				Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.							EC:5.6.2.1|MetaCyc:5.99.1.2-RXN		molecular_function											owl:Class	
GO:1901596	biolink:NamedThing	response to reversine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.	got7fsn_ti							mah	2012-11-07T17:17:01Z						biological_process											owl:Class	
GO:0102805	biolink:NamedThing	codeine O-demethylase activity	Catalysis of the reaction: codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + carbon dioxide.	got7fsn_ti												RHEA:27413|MetaCyc:RXN-8152|EC:1.14.11.32		molecular_function											owl:Class	
GO:0102415	biolink:NamedThing	quercetin gentiobioside 1,6-glucosyltransferase activity	Catalysis of the reaction: quercetin-3-gentiobioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotrioside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13798		molecular_function											owl:Class	
GO:0005166	biolink:NamedThing	neurotrophin p75 receptor binding	Binding to a neurotrophin p75 receptor.	got7fsn_ti	neurotrophin p75 receptor ligand													molecular_function											owl:Class	
GO:0016578	biolink:NamedThing	histone deubiquitination	The modification of histones by removal of ubiquitin groups.	got7fsn_ti	histone deubiquitylation|histone deubiquitinylation													biological_process											owl:Class	
GO:0060961	biolink:NamedThing	phospholipase D inhibitor activity	Binds to and stops, prevents or reduces the activity of phospholipase D.	got7fsn_ti							dph	2009-10-05T02:47:26Z						molecular_function											owl:Class	
GO:0051888	biolink:NamedThing	positive regulation of timing of exogen	Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.	got7fsn_ti	stimulation of exogen|positive regulation of exogen|up-regulation of exogen|up regulation of exogen|upregulation of exogen|activation of exogen													biological_process											owl:Class	
GO:0048818	biolink:NamedThing	positive regulation of hair follicle maturation	Any process that activates or increases the frequency, rate or extent of hair follicle maturation.	got7fsn_ti	stimulation of hair follicle maturation|up-regulation of hair follicle maturation|upregulation of hair follicle maturation|activation of hair follicle maturation|up regulation of hair follicle maturation													biological_process											owl:Class	
GO:0050951	biolink:NamedThing	sensory perception of temperature stimulus	The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti	sensory perception of thermal stimulus													biological_process											owl:Class	
GO:0018854	biolink:NamedThing	3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0737		molecular_function											owl:Class	
GO:0098606	biolink:NamedThing	selenocystathionine gamma-lyase activity	Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid.	got7fsn_ti							dos	2014-04-16T11:20:00Z				Reactome:R-HSA-2408543|RHEA:31151		molecular_function											owl:Class	
GO:0042256	biolink:NamedThing	mature ribosome assembly	The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.	got7fsn_ti														biological_process											owl:Class	
GO:0016613	biolink:NamedThing	vanadium-iron nitrogenase complex	An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.	got7fsn_ti	vanadium-iron nitrogenase activity													cellular_component											owl:Class	
GO:0021585	biolink:NamedThing	pons structural organization	The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	got7fsn_ti	pons structural organisation													biological_process											owl:Class	
GO:0106242	biolink:NamedThing	kolavenyl diphosphate synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate.	got7fsn_ti							hjd	2019-12-19T18:31:00Z				RHEA:54676|EC:5.5.1.29		molecular_function											owl:Class	
GO:0043994	biolink:NamedThing	histone acetyltransferase activity (H3-K23 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K23 specific)													molecular_function											owl:Class	
GO:0034295	biolink:NamedThing	basidiospore formation	The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium.	got7fsn_ti					Note that basidiospores and basidia are separate biological structures. The basidium is the structure that bear the basidiospores, but the development of the basidium is a different process than the formation of the basidiospores themselves. For this reason, GO:0034295 basidiospore formation and GO:0075313 basidium development are different terms and are not linked.									biological_process											owl:Class	
GO:0071608	biolink:NamedThing	macrophage inflammatory protein-1 alpha production	The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	macrophage inflammatory protein production|MIP-1a production|chemokine (C-C motif) ligand 3 production|CCL3 production						mah	2010-02-05T04:24:17Z						biological_process											owl:Class	
GO:0046358	biolink:NamedThing	butyrate biosynthetic process	The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid.	got7fsn_ti	butyrate anabolism|butanoic acid formation|butanoic acid anabolism|butanoic acid synthesis|butyrate synthesis|butyrate formation|butanoic acid biosynthetic process|butanoic acid biosynthesis|butyrate biosynthesis										GO:0043439			biological_process											owl:Class	
GO:0002438	biolink:NamedThing	acute inflammatory response to antigenic stimulus	An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.	got7fsn_ti														biological_process											owl:Class	
GO:0008703	biolink:NamedThing	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH.	got7fsn_ti	5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase activity|5-amino-6-(5'-phosphoribosylamino)uracil reductase activity|aminodioxyphosphoribosylaminopyrimidine reductase activity											KEGG_REACTION:R03458|EC:1.1.1.193|RHEA:17845|MetaCyc:RIBOFLAVINSYNREDUC-RXN		molecular_function											owl:Class	
GO:0050926	biolink:NamedThing	regulation of positive chemotaxis	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	got7fsn_ti														biological_process											owl:Class	
GO:0014915	biolink:NamedThing	regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction	Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0014880	biolink:NamedThing	regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction	Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0035192	biolink:NamedThing	nuclear cortical migration	The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0035190	biolink:NamedThing	syncytial nuclear migration	The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0019288	biolink:NamedThing	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.	got7fsn_ti	mevalonate-independent isopentenyl diphosphate biosynthesis|isopentenyl diphosphate synthesis, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, MEP pathway|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|isopentenyl diphosphate anabolism, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, non-mevalonate pathway|isopentenyl diphosphate formation, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, mevalonate-independent|isopentenyl diphosphate biosynthetic process via 1-deoxy-D-xylulose 5-phosphate|non-MVA pathway|mevalonate-independent isopentenyl diphosphate biosynthetic process|isopentenyl diphosphate biosynthesis, non-mevalonate pathway|isopentenyl diphosphate biosynthesis, mevalonate-independent											MetaCyc:NONMEVIPP-PWY		biological_process											owl:Class	
GO:0048617	biolink:NamedThing	embryonic foregut morphogenesis	The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0034450	biolink:NamedThing	ubiquitin-ubiquitin ligase activity	Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E4											Reactome:R-HSA-975122|Reactome:R-HSA-937050		molecular_function											owl:Class	
GO:0098942	biolink:NamedThing	retrograde trans-synaptic signaling by trans-synaptic protein complex	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0102777	biolink:NamedThing	caffeoyl-CoA:pelargonidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> pelargonidin-3,5-diglucoside-5-O-caffeoylglucoside + coenzyme A(4-).	got7fsn_ti												EC:2.3.1.153|MetaCyc:RXN-7842		molecular_function											owl:Class	
GO:1990439	biolink:NamedThing	MAP kinase serine/threonine phosphatase activity	Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate.	got7fsn_ti							al	2014-07-31T12:21:04Z						molecular_function											owl:Class	
GO:0030158	biolink:NamedThing	protein xylosyltransferase activity	Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate.	got7fsn_ti	UDP-D-xylose:core protein beta-D-xylosyltransferase activity|UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase activity|uridine diphosphoxylose-core protein beta-xylosyltransferase activity|peptide O-xylosyltransferase activity|UDP-D-xylose:protein beta-D-xylosyltransferase activity|UDP-xylose-core protein beta-D-xylosyltransferase activity|UDP-D-xylose:core protein xylosyltransferase activity|uridine diphosphoxylose-protein xylosyltransferase activity											RHEA:50192|MetaCyc:2.4.2.26-RXN|Reactome:R-HSA-1878002|EC:2.4.2.26		molecular_function											owl:Class	
GO:1990386	biolink:NamedThing	mitotic cleavage furrow ingression	Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.	got7fsn_ti							kmv	2014-05-29T20:58:27Z						biological_process											owl:Class	
GO:0047240	biolink:NamedThing	lactosylceramide beta-1,3-galactosyltransferase activity	Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H(+) + UDP.	got7fsn_ti	UDPgalactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity|UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity|uridine diphosphogalactose-lactosylceramide beta1->3-galactosyltransferase activity											KEGG_REACTION:R04431|MetaCyc:2.4.1.179-RXN|EC:2.4.1.179|RHEA:18413		molecular_function											owl:Class	
GO:0038002	biolink:NamedThing	endocrine signaling	The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other.	got7fsn_ti	endocrine signalling				This term should be used with caution, and only used when the signaling between cells has been clearly distinguished from paracrine signaling.		bf	2011-02-25T02:12:19Z						biological_process											owl:Class	
GO:0033382	biolink:NamedThing	maintenance of granzyme B location in T cell secretory granule	A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of granzyme B localization in T lymphocyte secretory granule|maintenance of granzyme B localization in T-lymphocyte secretory granule|maintenance of granzyme B localization in T cell secretory granule|maintenance of granzyme B localization in T-cell secretory granule													biological_process											owl:Class	
GO:0004107	biolink:NamedThing	chorismate synthase activity	Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.	got7fsn_ti	5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)|5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase activity|5-enolpyruvylshikimate-3-phosphate phospholyase activity											MetaCyc:CHORISMATE-SYNTHASE-RXN|EC:4.2.3.5|RHEA:21020|KEGG_REACTION:R01714		molecular_function											owl:Class	
GO:0050592	biolink:NamedThing	4-hydroxyphenylacetaldehyde oxime monooxygenase activity	Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+).	got7fsn_ti	4-hydroxybenzeneacetaldehyde oxime monooxygenase activity|cytochrome P450II-dependent monooxygenase activity|(Z)-4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity|CYP71E1 activity|cytochrome P450-II-dependent monooxygenase activity|NADPH-cytochrome P450 reductase (CYP71E1)|4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity											EC:1.14.14.37|KEGG_REACTION:R05728|MetaCyc:1.14.13.68-RXN|RHEA:18401		molecular_function											owl:Class	
GO:1903035	biolink:NamedThing	negative regulation of response to wounding	Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.	got7fsn_ti	negative regulation of physiological response to wounding|inhibition of physiological response to wounding|down-regulation of response to wounding|inhibition of response to wounding|down regulation of physiological response to wounding|downregulation of physiological response to wounding|downregulation of response to wounding|down-regulation of physiological response to wounding|down regulation of response to wounding						kmv	2014-05-18T01:28:52Z						biological_process											owl:Class	
GO:0097707	biolink:NamedThing	ferroptosis	A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes.	got7fsn_ti	iron-dependent programmed cell death						pr	2016-03-03T12:51:18Z						biological_process											owl:Class	
GO:0008215	biolink:NamedThing	spermine metabolic process	The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.	got7fsn_ti	spermine metabolism													biological_process											owl:Class	
GO:0097372	biolink:NamedThing	NAD-dependent histone deacetylase activity (H3-K18 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein.	got7fsn_ti							pr	2012-09-05T13:16:39Z						molecular_function											owl:Class	
GO:0140672	biolink:NamedThing	ATAC complex	A chromatin remodelling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation.	got7fsn_ti	Ada Two-A containing complex|KAT2A-containing ATAC complex|Ada-Two-A-containing complex|G-ATAC complex|ADA2A-containing complex|KAT2B-containing ATAC complex|Ada two A containing complex	https://github.com/geneontology/go-ontology/issues/21335					pg	2021-06-25T11:05:14Z						cellular_component											owl:Class	
GO:0031860	biolink:NamedThing	telomeric 3' overhang formation	The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.	got7fsn_ti	telomere end processing|telomere 3'-end processing													biological_process											owl:Class	
GO:0050269	biolink:NamedThing	coniferyl-aldehyde dehydrogenase activity	Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.	got7fsn_ti	coniferyl aldehyde:NAD(P)+ oxidoreductase activity											MetaCyc:RXN-1241|EC:1.2.1.68		molecular_function											owl:Class	
GO:0050455	biolink:NamedThing	columbamine oxidase activity	Catalysis of the reaction: 2 columbamine + O(2) = 2 berberine + 2 H(2)O.	got7fsn_ti	berberine synthase activity|columbamine:oxygen oxidoreductase (cyclizing)											MetaCyc:COLUMBAMINE-OXIDASE-RXN|EC:1.21.3.2|KEGG_REACTION:R00044|RHEA:23564		molecular_function											owl:Class	
GO:0103103	biolink:NamedThing	UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+.	got7fsn_ti												EC:2.4.1.195|MetaCyc:RXNQT-4328		molecular_function											owl:Class	
GO:0050590	biolink:NamedThing	desacetoxyvindoline 4-hydroxylase activity	Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2.	got7fsn_ti	deacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)|desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)|desacetoxyvindoline-4-hydroxylase activity|D17H activity|desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-hydroxylating) activity|desacetyoxyvindoline-17-hydroxylase activity											KEGG_REACTION:R05857|EC:1.14.11.20|RHEA:18973|MetaCyc:1.14.11.20-RXN		molecular_function											owl:Class	
GO:0065010	biolink:NamedThing	extracellular membrane-bounded organelle	Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.	got7fsn_ti	extracellular membrane-enclosed organelle													cellular_component											owl:Class	
GO:0099543	biolink:NamedThing	trans-synaptic signaling by soluble gas	Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft.	got7fsn_ti														biological_process											owl:Class	
GO:0052849	biolink:NamedThing	NADPH-dependent curcumin reductase activity	Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+.	got7fsn_ti							ai	2011-12-05T11:03:23Z				MetaCyc:RXN0-6676|EC:1.3.1.n3		molecular_function											owl:Class	
GO:0010151	biolink:NamedThing	chloroplast elongation	Expansion of the chloroplast that usually precedes division.	got7fsn_ti														biological_process											owl:Class	
GO:0046534	biolink:NamedThing	positive regulation of photoreceptor cell differentiation	Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	stimulation of photoreceptor cell differentiation|activation of photoreceptor cell differentiation|up-regulation of photoreceptor cell differentiation|up regulation of photoreceptor differentiation|stimulation of photoreceptor differentiation|up-regulation of photoreceptor differentiation|upregulation of photoreceptor differentiation|positive regulation of photoreceptor differentiation|upregulation of photoreceptor cell differentiation|activation of photoreceptor differentiation|up regulation of photoreceptor cell differentiation										GO:0045675			biological_process											owl:Class	
GO:0047067	biolink:NamedThing	hydrogen:quinone oxidoreductase activity	Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone.	got7fsn_ti	membrane-bound hydrogenase activity|quinone-reactive Ni/Fe-hydrogenase activity|hydrogen-ubiquinone oxidoreductase activity|hydrogen:menaquinone oxidoreductase activity											KEGG_REACTION:R02965|MetaCyc:1.12.5.1-RXN|EC:1.12.5.1|RHEA:18641		molecular_function											owl:Class	
GO:0086072	biolink:NamedThing	AV node cell-bundle of His cell adhesion involved in cell communication	The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	got7fsn_ti	atrioventricular node cell-bundle of His cell adhesion involved in cell communication						dph	2011-11-22T09:49:59Z						biological_process											owl:Class	
GO:1990319	biolink:NamedThing	collagen type XX trimer	A collagen homotrimer of alpha1(XX) chains.	got7fsn_ti							bhm	2014-03-14T16:31:21Z						cellular_component											owl:Class	
GO:0033780	biolink:NamedThing	taurochenodeoxycholate 6alpha-hydroxylase activity	Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O.	got7fsn_ti	taurochenodeoxycholate 6alpha-monooxygenase activity|CYP4A21|taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity|CYP3A4											MetaCyc:RXN-7977|EC:1.14.13.97|RHEA:23644		molecular_function											owl:Class	
GO:0004043	biolink:NamedThing	L-aminoadipate-semialdehyde dehydrogenase activity	Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.	got7fsn_ti	alpha-aminoadipate-semialdehyde dehydrogenase activity|AAR|2-aminoadipate semialdehyde dehydrogenase activity|alpha-aminoadipate reductase activity|aminoadipate semialdehyde dehydrogenase activity|2-aminoadipic semialdehyde dehydrogenase activity|L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity|L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity|L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase|L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity|aminoadipate-semialdehyde dehydrogenase activity											Reactome:R-HSA-70941|MetaCyc:1.2.1.31-RXN|EC:1.2.1.31|RHEA:12308		molecular_function											owl:Class	
GO:0004165	biolink:NamedThing	dodecenoyl-CoA delta-isomerase activity	Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA.	got7fsn_ti	delta3,Delta2-enoyl-CoA isomerase activity|dodecenoyl-CoA D-isomerase activity|acetylene-allene isomerase activity|dodecenoyl-CoA (3Z)-(2E)-isomerase activity|dodecenoyl-CoA Delta-isomerase activity|delta3-cis-delta2-trans-enoyl-CoA isomerase|dodecenoyl-CoA isomerase activity|delta(3),Delta(2)-enoyl-CoA isomerase activity|3,2-trans-enoyl-CoA isomerase activity|dodecenoyl-CoA delta3-cis-delta2-trans-isomerase activity|delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase activity										GO:0008461	EC:5.3.3.8|MetaCyc:ENOYL-COA-DELTA-ISOM-RXN|RHEA:23716|Reactome:R-HSA-109338|Reactome:R-HSA-6809808		molecular_function											owl:Class	
GO:0001632	biolink:NamedThing	leukotriene B4 receptor activity	Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate.	got7fsn_ti	BLT receptor													molecular_function											owl:Class	
GO:0075325	biolink:NamedThing	spore dispersal	Any process in which an organism disseminates its spores.	got7fsn_ti	spore dispersal on or near host during symbiotic interaction|passive spore dispersal on or near host|active spore dispersal on or near host during symbiotic interaction|spore dispersal on or near host|active spore dispersal on or near host	https://github.com/geneontology/go-ontology/issues/18823									GO:0075326|GO:0075327			biological_process											owl:Class	
GO:2000293	biolink:NamedThing	negative regulation of defecation	Any process that stops, prevents or reduces the frequency, rate or extent of defecation.	got7fsn_ti							bf	2010-12-21T09:23:13Z						biological_process											owl:Class	
GO:0051997	biolink:NamedThing	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity	Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2.	got7fsn_ti	OHCU decarboxylase activity|4-(carbamoylamino)-5-hydroxy-2-oxo-2,5-dihydro-1H-imidazole-5-carboxylate decarboxylase activity						ai	2010-07-19T10:47:15Z				RHEA:26301|MetaCyc:RXN-6201|KEGG_REACTION:R06604		molecular_function											owl:Class	
GO:0009037	biolink:NamedThing	tyrosine-based site-specific recombinase activity	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.	got7fsn_ti	site-specific tyrosine recombinase activity|tyrosine recombinase													molecular_function											owl:Class	
GO:0036123	biolink:NamedThing	histone H3-K9 dimethylation	The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone.	got7fsn_ti	histone lysine H3 K9 dimethylation|histone H3 K9 dimethylation						bf	2012-02-20T03:06:15Z						biological_process											owl:Class	
GO:0048027	biolink:NamedThing	mRNA 5'-UTR binding	Binding to an mRNA molecule at its 5' untranslated region.	got7fsn_ti	mRNA 5' UTR binding													molecular_function											owl:Class	
GO:0102090	biolink:NamedThing	adrenaline O-methyltransferase activity	Catalysis of the reaction: (R)-adrenaline(1+) + S-adenosyl-L-methionine  <=> metanephrine + S-adenosyl-L-homocysteine + H+.	got7fsn_ti												MetaCyc:RXN-10909		molecular_function											owl:Class	
GO:0044145	biolink:NamedThing	modulation of formation of structure involved in a symbiotic process	Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	got7fsn_ti	modulation of development of symbiont during interaction with host|modulation of development of symbiont involved in interaction with host	https://github.com/geneontology/go-ontology/issues/20305			This term partially replaces the obsolete term 'modulation of growth or development of symbiont during interaction with host ; GO:0075338'. See also 'modulation of growth of symbiont during interaction with host ; GO:0044144'.		jl	2009-08-06T01:57:38Z						biological_process											owl:Class	
GO:0002039	biolink:NamedThing	p53 binding	Binding to one of the p53 family of proteins.	got7fsn_ti														molecular_function											owl:Class	
GO:1990014	biolink:NamedThing	orthogonal array	Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels).	got7fsn_ti	orthogonal array of particles|OAP|square array						pr	2012-12-13T20:14:15Z				NIF_Subcellular:sao1747012216		cellular_component											owl:Class	
GO:0031573	biolink:NamedThing	mitotic intra-S DNA damage checkpoint signaling	A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.	got7fsn_ti	S-phase checkpoint|signal transduction involved in intra-S DNA damage checkpoint|mitotic intra-S DNA damage checkpoint|intra-S DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072428			biological_process											owl:Class	
GO:0044773	biolink:NamedThing	mitotic DNA damage checkpoint signaling	A signal transduction process involved in mitotic DNA damage checkpoint.	got7fsn_ti	mitotic DNA damage checkpoint|signal transduction involved in mitotic DNA damage checkpoint|intracellular signal transduction pathway involved in mitotic DNA damage checkpoint|intracellular signaling pathway involved in mitotic DNA damage checkpoint|intracellular signaling cascade involved in mitotic DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20935					jl	2013-02-28T15:55:25Z			GO:1902402			biological_process											owl:Class	
GO:0004448	biolink:NamedThing	isocitrate dehydrogenase activity	Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor.	got7fsn_ti	isocitric acid dehydrogenase activity|IDP3|oxalosuccinate carboxylase activity|IDP activity|oxalsuccinic decarboxylase activity|IDP1|beta-ketoglutaric-isocitric carboxylase activity|oxalosuccinate decarboxylase activity|IDH activity|IDP2|isocitric dehydrogenase activity											MetaCyc:ISOCITDEH-RXN		molecular_function											owl:Class	
GO:0036388	biolink:NamedThing	pre-replicative complex assembly	The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.	got7fsn_ti	pre-RC assembly|pre-replication complex assembly						bf	2013-06-05T16:29:13Z						biological_process											owl:Class	
GO:0006605	biolink:NamedThing	protein targeting	The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.	got7fsn_ti	nascent polypeptide association|protein sorting along secretory pathway				Note that protein targeting encompasses the transport of the protein to the specified location, and may also include additional steps such as protein processing.							Wikipedia:Protein_targeting		biological_process											owl:Class	
GO:1901617	biolink:NamedThing	organic hydroxy compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organic hydroxy compound.	got7fsn_ti	organic hydroxy compound anabolism|organic hydroxy compound synthesis|organic hydroxy compound formation|organic hydroxy compound biosynthesis						pr	2012-11-13T12:54:36Z						biological_process											owl:Class	
GO:0019140	biolink:NamedThing	inositol 3-kinase activity	Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate.	got7fsn_ti	inositol-1-kinase (phosphorylating)|ATP:myo-inositol 1-phosphotransferase activity|inositol 1-kinase activity|myo-inositol 3-kinase activity|myoinositol kinase activity|myo-inositol 1-kinase activity											RHEA:21804|MetaCyc:MYO-INOSITOL-1-KINASE-RXN|EC:2.7.1.64		molecular_function											owl:Class	
GO:0044467	biolink:NamedThing	glial cell-derived neurotrophic factor production	The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons.	got7fsn_ti	glial cell line-derived neurotrophic factor production|glial cell-derived neurotrophic factor secretion|GDNF production						jl	2012-01-17T04:26:05Z						biological_process											owl:Class	
GO:0033939	biolink:NamedThing	xylan alpha-1,2-glucuronosidase activity	Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.	got7fsn_ti	alpha-(1->2)-glucuronidase activity|1,2-alpha-glucuronidase activity|xylan alpha-D-1,2-(4-O-methyl)glucuronohydrolase activity											EC:3.2.1.131|MetaCyc:3.2.1.131-RXN		molecular_function											owl:Class	
GO:0003173	biolink:NamedThing	ventriculo bulbo valve development	The progression of the ventriculo bulbo valve over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-08T11:16:25Z						biological_process											owl:Class	
GO:0070007	biolink:NamedThing	glutamic-type endopeptidase activity	Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.	got7fsn_ti														molecular_function											owl:Class	
GO:0071566	biolink:NamedThing	UFM1 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti							mah	2010-01-20T04:06:05Z						molecular_function											owl:Class	
GO:0004325	biolink:NamedThing	ferrochelatase activity	Catalysis of the reaction: protoheme = Fe(2+) + protoporphyrin IX.	got7fsn_ti	ferro-protoporphyrin chelatase activity|protoheme ferro-lyase (protoporphyrin-forming)|heme synthetase activity|protoheme ferrolyase activity|protoheme ferro-lyase activity|heme synthase activity|iron chelatase activity											MetaCyc:PROTOHEMEFERROCHELAT-RXN|EC:4.99.1.1|KEGG_REACTION:R00310|Reactome:R-HSA-189465|RHEA:22584		molecular_function											owl:Class	
GO:0035200	biolink:NamedThing	leg disc anterior/posterior pattern formation	The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc.	got7fsn_ti														biological_process											owl:Class	
GO:0035223	biolink:NamedThing	leg disc pattern formation	The process that gives rise to the patterns of cell differentiation in the leg imaginal disc.	got7fsn_ti														biological_process											owl:Class	
GO:0047413	biolink:NamedThing	N(alpha)-benzyloxycarbonylleucine hydrolase activity	Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H(2)O + H(+) = L-leucine + benzyl alcohol + CO(2).	got7fsn_ti	benzyloxycarbonylleucine hydrolase activity|alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase activity|nalpha-benzyloxycarbonylleucine hydrolase activity|nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV											KEGG_REACTION:R02552|EC:3.5.1.64|RHEA:18901|MetaCyc:3.5.1.64-RXN		molecular_function											owl:Class	
GO:0002107	biolink:NamedThing	generation of mature 3'-end of 5S rRNA generated by RNA polymerase III	The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.	got7fsn_ti														biological_process											owl:Class	
GO:0039707	biolink:NamedThing	pore formation by virus in membrane of host cell	The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism.	got7fsn_ti	pore formation in membrane of host cell by virus|viroporin						bf	2013-11-25T15:33:33Z						biological_process											owl:Class	
GO:0061766	biolink:NamedThing	positive regulation of lung blood pressure	The process that increases the force with which blood travels through the lungs.	got7fsn_ti	positive regulation of pulmonary blood pressure						dph	2016-04-27T11:54:34Z						biological_process											owl:Class	
GO:0047432	biolink:NamedThing	2,2-dialkylglycine decarboxylase (pyruvate) activity	Catalysis of the reaction: 2,2-dialkylglycine + H(+) + pyruvate = L-alanine + CO(2) + dialkyl ketone.	got7fsn_ti	dialkyl amino acid (pyruvate) decarboxylase activity|L-alanine-alpha-ketobutyrate aminotransferase activity|alpha-dialkyl amino acid transaminase activity|2,2-dialkylglycine carboxy-lyase (amino-transferring)|dialkylamino-acid decarboxylase (pyruvate)|2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)|2,2-dialkyl-2-amino acid-pyruvate aminotransferase activity											EC:4.1.1.64|KEGG_REACTION:R03854|MetaCyc:4.1.1.64-RXN|RHEA:16073		molecular_function											owl:Class	
GO:0061289	biolink:NamedThing	Wnt signaling pathway involved in kidney development	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.	got7fsn_ti	Wnt receptor signaling pathway involved in kidney development|Wnt receptor signalling pathway involved in kidney development|Wnt-activated signaling pathway involved in kidney development						dph	2010-09-03T12:04:50Z						biological_process											owl:Class	
GO:0060995	biolink:NamedThing	cell-cell signaling involved in kidney development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.	got7fsn_ti	cell-cell signalling involved in kidney development						dph	2010-01-19T08:33:40Z						biological_process											owl:Class	
GO:0102419	biolink:NamedThing	sn-2-glycerol-3-phosphate omega-OH-C22:0-CoA acyl transferase activity	Catalysis of the reaction: omega-hydroxy-C22:0-CoA + sn-glycerol 3-phosphate = coenzyme A + 2-omega-hydroxy-C22:0-LPA.	got7fsn_ti												MetaCyc:RXN-13803|RHEA:33559|EC:2.3.1.198		molecular_function											owl:Class	
GO:0048743	biolink:NamedThing	positive regulation of skeletal muscle fiber development	Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	got7fsn_ti	positive regulation of skeletal myofiber development|activation of skeletal muscle fiber development|up regulation of skeletal muscle fiber development|positive regulation of skeletal myofibre development|stimulation of skeletal muscle fiber development|positive regulation of skeletal muscle fibre development|upregulation of skeletal muscle fiber development|up-regulation of skeletal muscle fiber development													biological_process											owl:Class	
GO:0004066	biolink:NamedThing	asparagine synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.	got7fsn_ti	asparagine synthase (glutamine-hydrolysing)|asparagine synthetase B activity|asparagine synthetase (glutamine-hydrolysing)|AS|glutamine-dependent asparagine synthetase activity|asparagine synthetase (glutamine-hydrolyzing) activity|L-aspartate:L-glutamine amido-ligase (AMP-forming)|AS-B activity											EC:6.3.5.4|Reactome:R-HSA-70599|MetaCyc:ASNSYNB-RXN|RHEA:12228		molecular_function											owl:Class	
GO:0099501	biolink:NamedThing	exocytic vesicle membrane	The lipid bilayer surrounding an exocytic vesicle.	got7fsn_ti	secretory vesicle membrane													cellular_component											owl:Class	
GO:0019688	biolink:NamedThing	purine deoxyribonucleoside interconversion	The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.	got7fsn_ti														biological_process											owl:Class	
GO:0046122	biolink:NamedThing	purine deoxyribonucleoside metabolic process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	purine deoxyribonucleoside metabolism													biological_process											owl:Class	
GO:0005601	biolink:NamedThing	classical-complement-pathway C3/C5 convertase complex	A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.	got7fsn_ti														cellular_component											owl:Class	
GO:0060711	biolink:NamedThing	labyrinthine layer development	The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.	got7fsn_ti							dph	2009-06-09T03:27:43Z						biological_process											owl:Class	
GO:0032136	biolink:NamedThing	adenine/cytosine mispair binding	Binding to a double-stranded DNA region containing an A/C mispair.	got7fsn_ti	C/A mispair binding|cytosine/adenine mispair binding|A/C mispair binding													molecular_function											owl:Class	
GO:0032529	biolink:NamedThing	follicle cell microvillus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.	got7fsn_ti	follicle cell microvillus organisation|follicle cell microvillus organization and biogenesis													biological_process											owl:Class	
GO:0035680	biolink:NamedThing	posterior lateral line neuromast hair cell morphogenesis	The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.	got7fsn_ti							bf	2011-02-14T11:08:14Z						biological_process											owl:Class	
GO:0097134	biolink:NamedThing	cyclin E1-CDK2 complex	A protein complex consisting of cyclin E1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:58:42Z						cellular_component											owl:Class	
GO:0060435	biolink:NamedThing	bronchiole development	The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.	got7fsn_ti														biological_process											owl:Class	
GO:0016724	biolink:NamedThing	oxidoreductase activity, acting on metal ions, oxygen as acceptor	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor.	got7fsn_ti	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor	https://github.com/geneontology/go-ontology/issues/20682										EC:1.16.3.-		molecular_function											owl:Class	
GO:0033207	biolink:NamedThing	beta-1,4-N-acetylgalactosaminyltransferase activity	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage.	got7fsn_ti	beta-1,4-GalNAc transferase activity													molecular_function											owl:Class	
GO:0090701	biolink:NamedThing	specification of plant organ identity	The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti							tb	2016-08-29T15:09:18Z						biological_process											owl:Class	
GO:2001157	biolink:NamedThing	negative regulation of proline catabolic process to glutamate	Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate.	got7fsn_ti	negative regulation of proline breakdown to glutamate|negative regulation of proline oxidation|negative regulation of proline degradation to glutamate						mcc	2011-10-25T08:54:43Z						biological_process											owl:Class	
GO:0010335	biolink:NamedThing	response to non-ionic osmotic stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.	got7fsn_ti														biological_process											owl:Class	
GO:0047256	biolink:NamedThing	lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity	Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.	got7fsn_ti	LA2 synthase activity|uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity|beta1->3-N-acetylglucosaminyltransferase activity|lactosylceramide beta-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity											EC:2.4.1.206|RHEA:13905|MetaCyc:2.4.1.206-RXN		molecular_function											owl:Class	
GO:0103056	biolink:NamedThing	gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A53 + O2 + 2-oxoglutarate <=> gibberellin A44 diacid + carbon dioxide + succinate.	got7fsn_ti												RHEA:60800|MetaCyc:RXN1F-167		molecular_function											owl:Class	
GO:0022019	biolink:NamedThing	dorsal lateral ganglionic eminence cell proliferation	The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0001787	biolink:NamedThing	natural killer cell proliferation	The expansion of a natural killer cell population by cell division.	got7fsn_ti	NK cell proliferation													biological_process											owl:Class	
GO:0030101	biolink:NamedThing	natural killer cell activation	The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti	NK cell activation													biological_process											owl:Class	
GO:0090223	biolink:NamedThing	chromatin-templated microtubule nucleation	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin.	got7fsn_ti							tb	2010-01-13T10:53:35Z						biological_process											owl:Class	
GO:0030079	biolink:NamedThing	light-harvesting complex, peripheral complex	Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center.	got7fsn_ti														cellular_component											owl:Class	
GO:1990111	biolink:NamedThing	spermatoproteasome complex	A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity.	got7fsn_ti							sp	2013-05-31T11:56:52Z						cellular_component											owl:Class	
GO:0005750	biolink:NamedThing	mitochondrial respiratory chain complex III	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.	got7fsn_ti	mitochondrial electron transport complex III|mitochondrial coenzyme Q-cytochrome c oxidoreductase complex|mitochondrial ubiquinol-cytochrome c oxidoreductase complex|mitochondrial cytochrome bc(1) complex|mitochondrial complex III|mitochondrial cytochrome bc1 complex|mitochondrial coenzyme Q-cytochrome c reductase complex|mitochondrial ubiquinol-cytochrome-c reductase complex										GO:0015008			cellular_component											owl:Class	
GO:0005516	biolink:NamedThing	calmodulin binding	Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.	got7fsn_ti														molecular_function											owl:Class	
GO:0033899	biolink:NamedThing	ribonuclease U2 activity	Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.	got7fsn_ti	pleospora RNase activity|purine-specific RNase activity|purine-specific ribonuclease activity|trichoderma koningi RNase III activity|RNase U2 activity|ribonuclease U2 activity|ribonuclease (purine) activity|purine specific endoribonuclease activity											MetaCyc:3.1.27.4-RXN|EC:4.6.1.20		molecular_function											owl:Class	
GO:0000981	biolink:NamedThing	DNA-binding transcription factor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.	got7fsn_ti	RNA polymerase II transcription factor activity, metal ion regulated core promoter proximal region sequence-specific binding|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding|RNA polymerase II transcription factor activity, zinc ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcription factor activity, copper ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcription factor activity, sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor activity, copper ion regulated core promoter proximal region sequence-specific binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|transcription factor|RNA polymerase II transcription factor activity, metal ion regulated proximal promoter sequence-specific DNA binding|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding|RNA polymerase II transcription factor activity, zinc ion regulated core promoter proximal region sequence-specific DNA binding|RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding|sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity|transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding|transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity	https://github.com/geneontology/go-ontology/issues/16131|https://github.com/geneontology/go-ontology/issues/15530|https://github.com/geneontology/go-ontology/issues/16152			For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2010-08-10T02:37:21Z			GO:0001202|GO:0001201|GO:0003705|GO:0000982|GO:0001200|GO:0001203|GO:0001133			molecular_function											owl:Class	
GO:0008678	biolink:NamedThing	2-deoxy-D-gluconate 3-dehydrogenase activity	Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+.	got7fsn_ti	2-keto-3-deoxygluconate oxidoreductase activity|2-deoxygluconate dehydrogenase activity|2-deoxy-D-gluconate:NAD+ 3-oxidoreductase activity											MetaCyc:KDUD-RXN|RHEA:12160|EC:1.1.1.125		molecular_function											owl:Class	
GO:0052868	biolink:NamedThing	protein-lysine lysyltransferase activity	Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine.	got7fsn_ti							ai	2012-01-11T03:05:27Z						molecular_function											owl:Class	
GO:0006006	biolink:NamedThing	glucose metabolic process	The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.	got7fsn_ti	glucose metabolism|cellular glucose metabolic process													biological_process											owl:Class	
GO:0019318	biolink:NamedThing	hexose metabolic process	The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.	got7fsn_ti	hexose metabolism													biological_process											owl:Class	
GO:0004313	biolink:NamedThing	[acyl-carrier-protein] S-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein].	got7fsn_ti	[acyl-carrier protein] S-acetyltransferase activity|ACP acetyltransferase activity|acetyl coenzyme A-acyl-carrier-protein transacylase activity|acyl-carrier-protein acetyltransferase activity|acyl-carrier-proteinacetyltransferase activity|acetyl-CoA:acyl-carrier-protein S-acetyltransferase activity|ACAT activity|ACP S-acetyltransferase activity|ACPacetyltransferase activity|acyl-carrier-protein S-acetyltransferase activity											MetaCyc:ACP-S-ACETYLTRANSFER-RXN|EC:2.3.1.38|RHEA:41788		molecular_function											owl:Class	
GO:0044868	biolink:NamedThing	modulation by host of viral molecular function	A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected.	got7fsn_ti							jl	2014-09-18T13:34:27Z						biological_process											owl:Class	
GO:0080011	biolink:NamedThing	baruol synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol.	got7fsn_ti												RHEA:31987|MetaCyc:RXN-9685|EC:5.4.99.57		molecular_function											owl:Class	
GO:0039524	biolink:NamedThing	suppression by virus of host mRNA processing	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.	got7fsn_ti	inhibition of host mRNA processing by virus|inhibition by virus of host mRNA processing|negative regulation by virus of host mRNA processing|inhibition of host pre-mRNA processing by virus						bf	2011-06-22T04:51:55Z				VZ:903		biological_process											owl:Class	
GO:0008813	biolink:NamedThing	chorismate lyase activity	Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate.	got7fsn_ti	4-hydroxybenzoate synthetase activity|chorismate pyruvate lyase activity|CL|chorismate pyruvate-lyase (4-hydroxybenzoate-forming) activity|CPL|UbiC											RHEA:16505|MetaCyc:CHORPYRLY-RXN|KEGG_REACTION:R01302|EC:4.1.3.40		molecular_function											owl:Class	
GO:0097675	biolink:NamedThing	SCF-Hrt3/Pof7 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe).	got7fsn_ti							pr	2014-10-06T10:31:14Z						cellular_component											owl:Class	
GO:1990820	biolink:NamedThing	response to mitotic DNA integrity checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.	got7fsn_ti	response to signal involved in mitotic DNA integrity checkpoint						mah	2015-08-14T10:25:46Z						biological_process											owl:Class	
GO:0052657	biolink:NamedThing	guanine phosphoribosyltransferase activity	Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate.	got7fsn_ti	purine-6-thiol phosphoribosyltransferase activity|guanine-hypoxanthine phosphoribosyltransferase activity|hypoxanthine-guanine phosphoribosyltransferase activity|guanosine phosphoribosyltransferase activity|Transphosphoribosidase activity|6-hydroxypurine phosphoribosyltransferase activity|guanylic pyrophosphorylase activity|GMP pyrophosphorylase activity|guanosine 5'-phosphate pyrophosphorylase activity|guanylate pyrophosphorylase activity|GPRT|6-mercaptopurine phosphoribosyltransferase activity											EC:2.4.2.8|KEGG_REACTION:R01229|MetaCyc:GUANPRIBOSYLTRAN-RXN|RHEA:25424		molecular_function											owl:Class	
GO:0050347	biolink:NamedThing	trans-octaprenyltranstransferase activity	Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + diphosphate.	got7fsn_ti	solanesyl pyrophosphate synthetase activity|all-trans-nonaprenyl-diphosphate synthase activity|terpenyl pyrophosphate synthetase activity|terpenoidallyltransferase activity|solanesyl-diphosphate synthase activity|(E)-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenyltranstransferase activity|polyprenylpyrophosphate synthetase activity|SPP synthase activity|nonaprenyl pyrophosphate synthetase activity|trans-prenyltransferase activity											RHEA:11324|KEGG_REACTION:R07267		molecular_function											owl:Class	
GO:0002439	biolink:NamedThing	chronic inflammatory response to antigenic stimulus	A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual.	got7fsn_ti														biological_process											owl:Class	
GO:0018003	biolink:NamedThing	peptidyl-lysine N6-acetylation	The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine.	got7fsn_ti					See also the molecular function term 'tubulin N-acetyltransferase activity ; GO:0019799'.							RESID:AA0055		biological_process											owl:Class	
GO:0071618	biolink:NamedThing	lysophosphatidylethanolamine acyltransferase activity	Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine.	got7fsn_ti							mah	2010-02-08T04:59:07Z						molecular_function											owl:Class	
GO:0001147	biolink:NamedThing	transcription termination site sequence-specific DNA binding	Binding to a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.	got7fsn_ti	transcription factor activity, mitochondrial RNA polymerase terminator site sequence-specific binding|transcription termination site DNA binding|bacterial-type RNA polymerase termination site sequence-specific DNA binding|mitochondrial RNA polymerase terminator site sequence-specific DNA binding transcription factor activity|mitochondrial RNA polymerase termination site sequence-specific DNA binding				Transcription termination sites can be recognized by the RNA polymerase (RNAP) itself or by another protein which interacts with the RNAP to promote transcription termination. Note that not all genes have a DNA specific sequence that functions as a termination site; for most mRNAs transcribed by RNAP II termination is not mediated by a specific termination sequence, but is coupled to polyadenylation.		krc	2011-01-27T02:42:23Z			GO:0001148|GO:0001146|GO:0001160|GO:0001145			molecular_function											owl:Class	
GO:0102918	biolink:NamedThing	(R)-reticuline 7-O-methyltransferase activity	Catalysis of the reaction: (R)-reticulinium(1+) + S-adenosyl-L-methionine  <=> (R)-laudanine(1+) + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-8701|EC:2.1.1.291|RHEA:38907		molecular_function											owl:Class	
GO:0070764	biolink:NamedThing	gamma-secretase-Delta1 complex	A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex.	got7fsn_ti							mah	2009-06-29T01:11:51Z						cellular_component											owl:Class	
GO:0036051	biolink:NamedThing	protein localization to trailing edge	A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.	got7fsn_ti	protein localisation to trailing edge						bf	2011-12-12T10:44:04Z						biological_process											owl:Class	
GO:0018847	biolink:NamedThing	alpha-pinene lyase activity	Catalysis of the reaction: alpha-pinene = limonene.	got7fsn_ti												EC:5.5.1.-|UM-BBD_reactionID:r0712		molecular_function											owl:Class	
GO:0034454	biolink:NamedThing	microtubule anchoring at centrosome	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.	got7fsn_ti														biological_process											owl:Class	
GO:0072393	biolink:NamedThing	microtubule anchoring at microtubule organizing center	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center.	got7fsn_ti	microtubule anchoring at microtubule organising centre|microtubule anchoring at MTOC						mah	2010-12-07T11:54:35Z						biological_process											owl:Class	
GO:0035260	biolink:NamedThing	internal genitalia morphogenesis	The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.	got7fsn_ti														biological_process											owl:Class	
GO:0030735	biolink:NamedThing	carnosine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:carnosine N-methyltransferase activity											EC:2.1.1.22|KEGG_REACTION:R02144|MetaCyc:CARNOSINE-N-METHYLTRANSFERASE-RXN|RHEA:14205|Reactome:R-HSA-8876789		molecular_function											owl:Class	
GO:0030770	biolink:NamedThing	demethylmacrocin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin.	got7fsn_ti	demethylmacrocin methyltransferase activity|S-adenosyl-L-methionine:demethylmacrocin 2'''-O-methyltransferase activity											EC:2.1.1.102|RHEA:17573|KEGG_REACTION:R02859|MetaCyc:DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0090582	biolink:NamedThing	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0050504	biolink:NamedThing	mannosyl-3-phosphoglycerate synthase activity	Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+).	got7fsn_ti	MPG synthase activity|GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase activity											RHEA:13537|EC:2.4.1.217|MetaCyc:2.4.1.217-RXN|KEGG_REACTION:R05768		molecular_function											owl:Class	
GO:1990145	biolink:NamedThing	maintenance of translational fidelity	Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.	got7fsn_ti							hjd	2013-07-24T19:30:09Z						biological_process											owl:Class	
GO:0018754	biolink:NamedThing	ammelide aminohydrolase activity	Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.	got7fsn_ti												MetaCyc:RXN-8017		molecular_function											owl:Class	
GO:0039505	biolink:NamedThing	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex.	got7fsn_ti	inhibition of host MHC class II molecule presentation by virus						bf	2011-06-02T02:34:51Z				VZ:820		biological_process											owl:Class	
GO:0052762	biolink:NamedThing	gellan lyase activity	Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).	got7fsn_ti							ai	2011-09-29T03:19:25Z				MetaCyc:RXN-12269|EC:4.2.2.25		molecular_function											owl:Class	
GO:0019551	biolink:NamedThing	glutamate catabolic process to 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate.	got7fsn_ti	glutamate catabolism to 2-ketoglutarate|glutamate catabolic process to 2-ketoglutarate|glutamate breakdown to 2-oxoglutarate|glutamate catabolism to alpha-ketoglutarate|glutamate catabolism to alpha-oxoglutarate|glutamate degradation to 2-oxoglutarate|glutamate catabolic process to alpha-ketoglutarate|glutamate catabolic process to alpha-oxoglutarate											MetaCyc:PWY-5766|MetaCyc:GLUTAMATE-DEG1-PWY		biological_process											owl:Class	
GO:0006106	biolink:NamedThing	fumarate metabolic process	The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.	got7fsn_ti	fumarate metabolism													biological_process											owl:Class	
GO:0046979	biolink:NamedThing	TAP2 binding	Binding to the TAP2 subunit of TAP (transporter associated with antigen processing) protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0046977	biolink:NamedThing	TAP binding	Binding to TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2.	got7fsn_ti														molecular_function											owl:Class	
GO:0047005	biolink:NamedThing	16-alpha-hydroxysteroid dehydrogenase activity	Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.	got7fsn_ti	16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase activity|16alpha-hydroxysteroid dehydrogenase activity|16alpha-hydroxy steroid dehydrogenase activity											MetaCyc:1.1.1.147-RXN|EC:1.1.1.147		molecular_function											owl:Class	
GO:0075198	biolink:NamedThing	modulation of symbiont haustorium neck formation for entry into host	Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0000253	biolink:NamedThing	3-keto sterol reductase activity	Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H(+).	got7fsn_ti	3-keto-steroid reductase activity|3beta-hydroxy-steroid:NADP+ 3-oxidoreductase|3-KSR activity				Note that zymosterol is cholesta-8,24-dien-3-ol.						GO:0050576	Reactome:R-HSA-194632|MetaCyc:RXN3O-4110|MetaCyc:RXN66-319|MetaCyc:RXN66-24|Reactome:R-HSA-194689|MetaCyc:RXN66-19|MetaCyc:RXN66-314|MetaCyc:1.1.1.270-RXN|RHEA:18409|EC:1.1.1.270		molecular_function											owl:Class	
GO:0031569	biolink:NamedThing	mitotic G2 cell size control checkpoint signaling	A signal transduction process that contributes to a cell size control checkpoint prior to the G2/M transition of mitosis.	got7fsn_ti	signal transduction involved in mitotic cell cycle G2/M transition size control checkpoint|G2/M transition size control checkpoint|signal transduction involved in G2 cell size control checkpoint|G2 cell size control checkpoint|signal transduction involved in G2/M transition size control checkpoint|mitotic cell cycle G2/M transition size control checkpoint|mitotic G2 cell size control checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072453			biological_process											owl:Class	
GO:0033326	biolink:NamedThing	cerebrospinal fluid secretion	The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces.	got7fsn_ti	CSF secretion													biological_process											owl:Class	
GO:0045518	biolink:NamedThing	interleukin-22 receptor binding	Binding to an interleukin-22 receptor.	got7fsn_ti	interleukin-22 receptor ligand|IL-22													molecular_function											owl:Class	
GO:1990503	biolink:NamedThing	dendritic lamellar body	A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions.	got7fsn_ti	DLB						sl	2014-09-30T20:47:28Z						cellular_component											owl:Class	
GO:0018038	biolink:NamedThing	C-terminal peptidyl-cysteine amidation	The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0085		biological_process											owl:Class	
GO:0045159	biolink:NamedThing	myosin II binding	Binding to a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.	got7fsn_ti														molecular_function											owl:Class	
GO:0061948	biolink:NamedThing	premature acrosome loss	The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.	got7fsn_ti	spontaneous acrosome loss				If the release of the acrosome content when the sperm reaches to the zona pellucida, consider using acrosome reaction.		dph	2017-10-25T17:46:55Z						biological_process											owl:Class	
GO:0010130	biolink:NamedThing	anaerobic ethylbenzene catabolic process	The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen.	got7fsn_ti	anaerobic ethylbenzene degradation|anaerobic ethylbenzene breakdown|anaerobic ethylbenzene catabolism											MetaCyc:PWY-481		biological_process											owl:Class	
GO:0018913	biolink:NamedThing	anaerobic ethylbenzene metabolic process	The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen.	got7fsn_ti	anaerobic ethylbenzene metabolism											UM-BBD_pathwayID:ethb		biological_process											owl:Class	
GO:0103082	biolink:NamedThing	2-(4'-methylthio)butylmalate synthase activity	Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + acetyl-CoA + H2O <=> H+ + 2-(4'-methylthio)butylmalate + coenzyme A.	got7fsn_ti												MetaCyc:RXNQT-4166		molecular_function											owl:Class	
GO:0018230	biolink:NamedThing	peptidyl-L-cysteine S-palmitoylation	The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.	got7fsn_ti	peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-cysteine S-palmitoylation				Palmitoylation of a non-terminal cysteine residue always occurs on a sulfur (S) atom.							RESID:AA0106		biological_process											owl:Class	
GO:0018231	biolink:NamedThing	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids.	got7fsn_ti	peptidyl-S-diacylglycerol-L-cysteine formation from peptidyl-cysteine|peptidyl-S-diacylglycerol-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-diacylglycerol-L-cysteine anabolism from peptidyl-cysteine											RESID:AA0107		biological_process											owl:Class	
GO:0098969	biolink:NamedThing	neurotransmitter receptor transport to postsynaptic membrane	The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:0050148	biolink:NamedThing	nucleotide diphosphokinase activity	Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate.	got7fsn_ti	ATP nucleotide 3'-pyrophosphokinase activity|nucleotide pyrophosphokinase activity|ATP:nucleotide pyrophosphotransferase activity|nucleotide 3'-pyrophosphokinase activity|ATP:nucleoside-5'-phosphate diphosphotransferase activity											RHEA:12713|MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN|EC:2.7.6.4		molecular_function											owl:Class	
GO:0046938	biolink:NamedThing	phytochelatin biosynthetic process	The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.	got7fsn_ti	phytochelatin biosynthesis|cadystin biosynthetic process|phytochelatin synthesis|phytochelatin formation|phytochelatin anabolism													biological_process											owl:Class	
GO:0033991	biolink:NamedThing	aldos-2-ulose dehydratase activity	Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one.	got7fsn_ti	AUDH|pyranosone dehydratase activity|1,5-anhydro-D-fructose dehydratase (microthecin-forming) activity|1,5-anhydro-D-fructose hydro-lyase (microthecin-forming) activity											EC:4.2.1.110|RHEA:12100|MetaCyc:4.2.1.110-RXN		molecular_function											owl:Class	
GO:0033957	biolink:NamedThing	lambda-carrageenase activity	Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S.	got7fsn_ti	endo-beta-1,4-carrageenose 2,6,2'-trisulfate-hydrolase activity											MetaCyc:3.2.1.162-RXN|EC:3.2.1.162		molecular_function											owl:Class	
GO:0099562	biolink:NamedThing	maintenance of postsynaptic density structure	A process which maintains the organization and the arrangement of proteins in the presynaptic density.	got7fsn_ti														biological_process											owl:Class	
GO:0046374	biolink:NamedThing	teichoic acid metabolic process	The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.	got7fsn_ti	teichoic acid metabolism													biological_process											owl:Class	
GO:0044495	biolink:NamedThing	modulation of blood pressure in other organism	A process by which one organism modulates the force with which blood travels through the circulatory system of another organism.	got7fsn_ti	regulation of blood pressure in other organism						jl	2012-02-01T02:10:15Z						biological_process											owl:Class	
GO:0042077	biolink:NamedThing	protein phosphate-linked glycosylation via serine	The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.	got7fsn_ti	protein amino acid phosphate-linked glycosylation via serine													biological_process											owl:Class	
GO:0042076	biolink:NamedThing	protein phosphate-linked glycosylation	The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.	got7fsn_ti	phosphoglycosylation|protein amino acid phosphate-linked glycosylation													biological_process											owl:Class	
GO:0051676	biolink:NamedThing	pullulan metabolic process	The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.	got7fsn_ti	pullulan metabolism													biological_process											owl:Class	
GO:0061301	biolink:NamedThing	cerebellum vasculature morphogenesis	The process in which the vasculature of the cerebellum is generated and organized.	got7fsn_ti							dph	2010-09-06T03:38:05Z						biological_process											owl:Class	
GO:0008693	biolink:NamedThing	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O.	got7fsn_ti	D-3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity|beta-hydroxydecanoyl thiol ester dehydrase activity|beta-hydroxyacyl-acyl carrier protein dehydratase activity|3-hydroxydecanoyl-acyl carrier protein dehydratase activity|3-hydroxydecanoyl-acyl carrier protein dehydrase activity|beta-hydroxyacyl-ACP dehydrase activity|HDDase activity|3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity|(3R)-3-hydroxydecanoyl-acyl-carrier-protein hydro-lyase activity|3-hydroxydecanoyl-ACP dehydratase activity|D-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity|3-hydroxydecanoyl-[acyl-carrier protein] dehydratase activity|FabA|beta-hydroxydecanoate dehydrase activity|beta-hydroxydecanoyl thioester dehydrase activity											EC:4.2.1.59|RHEA:41860		molecular_function											owl:Class	
GO:1903037	biolink:NamedThing	regulation of leukocyte cell-cell adhesion	Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion.	got7fsn_ti	regulation of leukocyte adhesion|regulation of leukocyte cell adhesion				Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion		rl	2014-05-19T15:29:58Z						biological_process											owl:Class	
GO:0070493	biolink:NamedThing	thrombin-activated receptor signaling pathway	The series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.	got7fsn_ti	thrombin receptor signalling pathway|thrombin receptor signaling pathway													biological_process											owl:Class	
GO:0098662	biolink:NamedThing	inorganic cation transmembrane transport	A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	monovalent inorganic cation transport|transmembrane inorganic cation transport|divalent inorganic cation transport|inorganic cation membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.						GO:0072511|GO:0015672			biological_process											owl:Class	
GO:0045277	biolink:NamedThing	respiratory chain complex IV	A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).	got7fsn_ti	cytochrome c oxidase complex|electron transport complex IV										GO:0045287			cellular_component											owl:Class	
GO:0102244	biolink:NamedThing	3-aminopropanal dehydrogenase activity	Catalysis of the reaction: 3-ammoniopropanal + NAD + H2O <=> 2 H+ + beta-alanine  + NADH.	got7fsn_ti												MetaCyc:RXN-12332		molecular_function											owl:Class	
GO:0098630	biolink:NamedThing	aggregation of unicellular organisms	The clustering together of unicellular organisms in suspension form aggregates.	got7fsn_ti	aggregation of single cell organisms													biological_process											owl:Class	
GO:0098743	biolink:NamedThing	cell aggregation	The clustering together and adhesion of initially separate cells to form an aggregate.  Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.	got7fsn_ti														biological_process											owl:Class	
GO:0044348	biolink:NamedThing	plant-type cell wall cellulose catabolic process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.	got7fsn_ti	plant-type cell wall polysaccharide breakdown						jl	2011-07-28T01:48:23Z						biological_process											owl:Class	
GO:0036213	biolink:NamedThing	contractile ring contraction	The process of an actomyosin ring getting smaller in diameter.	got7fsn_ti	contractile ring constriction	https://github.com/geneontology/go-ontology/issues/21855			This term can be used to annotate contraction of either bacterial or fungal contractile rings.		bf	2012-04-26T02:58:18Z						biological_process											owl:Class	
GO:0062196	biolink:NamedThing	regulation of lysosome size	Any process that modulates the size of a lysosome.	got7fsn_ti							dph	2019-12-09T21:06:44Z						biological_process											owl:Class	
GO:0140026	biolink:NamedThing	contractile vacuole dissociation from plasma membrane	The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network.	got7fsn_ti	contractile vacuole detethering from plasma membrane						pg	2017-05-02T10:16:12Z						biological_process											owl:Class	
GO:0018297	biolink:NamedThing	protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine	The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine.	got7fsn_ti												RESID:AA0221		biological_process											owl:Class	
GO:0042551	biolink:NamedThing	neuron maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.	got7fsn_ti														biological_process											owl:Class	
GO:0047857	biolink:NamedThing	dihydrouracil oxidase activity	Catalysis of the reaction: 5,6-dihydrouracil + O(2) = H(2)O(2) + uracil.	got7fsn_ti	5,6-dihydrouracil:oxygen oxidoreductase activity											RHEA:12384|KEGG_REACTION:R00975|EC:1.3.3.7|MetaCyc:DIHYDROURACIL-OXIDASE-RXN		molecular_function											owl:Class	
GO:0061662	biolink:NamedThing	ISG15 ligase activity	Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S --> X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3						dph	2014-11-06T13:54:48Z						molecular_function											owl:Class	
GO:0034354	biolink:NamedThing	'de novo' NAD biosynthetic process from tryptophan	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.	got7fsn_ti	de novo NAD biosynthetic process from tryptophan													biological_process											owl:Class	
GO:0102701	biolink:NamedThing	tricyclene synthase activity	Catalysis of the reaction: geranyl diphosphate(3-) <=> tricyclene + diphosphoric acid.	got7fsn_ti												RHEA:32687|EC:4.2.3.105|MetaCyc:RXN-5121		molecular_function											owl:Class	
GO:0006475	biolink:NamedThing	internal protein amino acid acetylation	The addition of an acetyl group to a non-terminal amino acid in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0002063	biolink:NamedThing	chondrocyte development	The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.	got7fsn_ti														biological_process											owl:Class	
GO:0007535	biolink:NamedThing	donor selection	The process that determines which donor locus a cell uses, in preference to another, in mating type switching.	got7fsn_ti	donor preference													biological_process											owl:Class	
GO:0004633	biolink:NamedThing	phosphopantothenoylcysteine decarboxylase activity	Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H(+) = CO(2) + pantetheine 4'-phosphate.	got7fsn_ti	N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming)|N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase activity|PPC-decarboxylase activity|N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase activity|4-phosphopantothenoyl-L-cysteine decarboxylase activity|4-phosphopantotheoylcysteine decarboxylase activity											MetaCyc:P-PANTOCYSDECARB-RXN|EC:4.1.1.36|Reactome:R-HSA-196840|RHEA:16793|KEGG_REACTION:R03269		molecular_function											owl:Class	
GO:0022614	biolink:NamedThing	membrane to membrane docking	The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere.	got7fsn_ti	membrane-membrane docking													biological_process											owl:Class	
GO:0001635	biolink:NamedThing	calcitonin gene-related peptide receptor activity	Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity.	got7fsn_ti	CGRP receptor|calcitonin gene-related polypeptide receptor activity											Wikipedia:CALCRL		molecular_function											owl:Class	
GO:0035125	biolink:NamedThing	embryonic anal fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.	got7fsn_ti														biological_process											owl:Class	
GO:0102186	biolink:NamedThing	4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 <=> 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + H2O.	got7fsn_ti												MetaCyc:RXN-11948		molecular_function											owl:Class	
GO:0052826	biolink:NamedThing	inositol hexakisphosphate 2-phosphatase activity	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate.	got7fsn_ti	1D-myo-inositol-hexakisphosphate 2-phosphohydrolase activity						ai	2011-11-29T09:52:14Z				EC:3.1.3.62|Reactome:R-HSA-1855225		molecular_function											owl:Class	
GO:0060019	biolink:NamedThing	radial glial cell differentiation	The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0102241	biolink:NamedThing	soyasaponin III rhamnosyltransferase activity	Catalysis of the reaction: UDP-L-rhamnose + soyasaponin III <=> H+ + UDP + soyasaponin I.	got7fsn_ti												MetaCyc:RXN-12320|RHEA:31491|EC:2.4.1.273		molecular_function											owl:Class	
GO:0004525	biolink:NamedThing	ribonuclease III activity	Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.	got7fsn_ti	ribonuclease 3 activity|RNase III activity|pre-mRNA 3'-end processing endonuclease											Reactome:R-HSA-426464|MetaCyc:3.1.26.3-RXN|EC:3.1.26.3|Reactome:R-HSA-203893|Reactome:R-HSA-203862		molecular_function											owl:Class	
GO:0008671	biolink:NamedThing	2-dehydro-3-deoxygalactonokinase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H(+).	got7fsn_ti	ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase activity|2-keto-3-deoxygalactonate kinase (phosphorylating)|2-keto-3-deoxy-galactonokinase activity|2-oxo-3-deoxygalactonate kinase activity|2-keto-3-deoxygalactonokinase activity											EC:2.7.1.58|MetaCyc:DEHYDDEOXGALACTKIN-RXN|RHEA:16525|KEGG_REACTION:R03387		molecular_function											owl:Class	
GO:0036212	biolink:NamedThing	contractile ring maintenance	The process in which the contractile ring is maintained, typically in response to an internal or external cue.	got7fsn_ti					This term can be used to annotate maintenance of either bacterial or fungal contractile rings.		bf	2012-04-26T02:57:39Z						biological_process											owl:Class	
GO:0036360	biolink:NamedThing	sorocarp stalk morphogenesis	The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	fruiting body stalk morphogenesis						bf	2012-09-20T11:21:30Z						biological_process											owl:Class	
GO:0090498	biolink:NamedThing	extrinsic component of Golgi membrane	The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to Golgi membrane						tb	2012-10-18T14:12:48Z						cellular_component											owl:Class	
GO:0034335	biolink:NamedThing	DNA negative supercoiling activity	Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria.	got7fsn_ti	DNA gyrase activity|DNA-gyrase activity				Note that this term was reinstated from obsolete.									molecular_function											owl:Class	
GO:0050530	biolink:NamedThing	glucosylglycerol 3-phosphatase activity	Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H(2)O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate.	got7fsn_ti	StpA|salt tolerance protein A|2-(beta-D-glucosyl)-sn-glycerol-3-phosphate phosphohydrolase activity											MetaCyc:3.1.3.69-RXN|EC:3.1.3.69|KEGG_REACTION:R05791|RHEA:22652		molecular_function											owl:Class	
GO:0097118	biolink:NamedThing	neuroligin clustering involved in postsynaptic membrane assembly	The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.	got7fsn_ti	neuroligin clustering|Nlgn clustering|postsynaptic neuroligin clustering						pr	2011-07-31T05:47:25Z						biological_process											owl:Class	
GO:0097732	biolink:NamedThing	9+2 non-motile cilium	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).	got7fsn_ti	9+2 immotile cilium|non-motile 9+2 cilium				This type of cilia may be present in solitary (e.g. in inner hair cells) or in multiple copies (e.g. in olfactory neurons).		pr	2016-09-29T14:07:33Z						cellular_component											owl:Class	
GO:0097730	biolink:NamedThing	non-motile cilium	A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.	got7fsn_ti	immotile primary cilium|nonmotile primary cilia|immotile cilium|sensory cilium|nonmotile cilium|nonmotile primary cilium						pr	2016-09-29T14:02:11Z			GO:0031513			cellular_component											owl:Class	
GO:0046351	biolink:NamedThing	disaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units.	got7fsn_ti	disaccharide formation|disaccharide biosynthesis|disaccharide synthesis|disaccharide anabolism													biological_process											owl:Class	
GO:0033548	biolink:NamedThing	myo-inositol hexakisphosphate biosynthetic process, lipid-independent	The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate.	got7fsn_ti	myo-inositol hexakisphosphate biosynthesis, lipid-independent|phytate biosynthesis, lipid-independent|myo-inositol hexakisphosphate anabolism, lipid-independent|myo-inositol hexakisphosphate synthesis, lipid-independent|myo-inositol hexakisphosphate formation, lipid-independent|phytate biosynthetic process, lipid-independent											MetaCyc:PWY-4661		biological_process											owl:Class	
GO:0072658	biolink:NamedThing	maintenance of protein location in membrane	Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.	got7fsn_ti							mah	2011-02-14T02:39:41Z						biological_process											owl:Class	
GO:0050168	biolink:NamedThing	pentanamidase activity	Catalysis of the reaction: H(2)O + pentanamide = NH(4)(+) + valerate.	got7fsn_ti	pentanamide amidohydrolase activity|valeramidase activity											EC:3.5.1.50|KEGG_REACTION:R02938|RHEA:10000|MetaCyc:PENTANAMIDASE-RXN		molecular_function											owl:Class	
GO:0102718	biolink:NamedThing	TRIBOA-glucoside methyltransferase activity	Catalysis of the reaction: TRIBOA-beta-D-glucoside + S-adenosyl-L-methionine  <=> (2R)-DIMBOA glucoside + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												RHEA:32099|MetaCyc:RXN-6687|EC:2.1.1.241		molecular_function											owl:Class	
GO:0060683	biolink:NamedThing	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.	got7fsn_ti	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signalling						dph	2009-06-03T06:30:56Z						biological_process											owl:Class	
GO:0030537	biolink:NamedThing	larval behavior	Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics.	got7fsn_ti	larval behaviour				See also the biological process term 'behavior ; GO:0007610'.						GO:0017037			biological_process											owl:Class	
GO:0035760	biolink:NamedThing	cytoplasmic polyadenylation-dependent rRNA catabolic process	The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.	got7fsn_ti	cytoplasmic poly(A)-dependent rRNA catabolic process						bf	2011-03-25T02:14:50Z						biological_process											owl:Class	
GO:0043634	biolink:NamedThing	polyadenylation-dependent ncRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.	got7fsn_ti	poly(A)-dependent ncRNA catabolic process													biological_process											owl:Class	
GO:0014832	biolink:NamedThing	urinary bladder smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.	got7fsn_ti														biological_process											owl:Class	
GO:0035280	biolink:NamedThing	miRNA loading onto RISC involved in gene silencing by miRNA	The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC).	got7fsn_ti	microRNA loading onto RISC involved in gene silencing by microRNA|miRNA-mediated gene silencing, miRNA loading onto RISC|miRISC assembly|gene silencing by miRNA, miRNA loading onto RISC													biological_process											owl:Class	
GO:0002521	biolink:NamedThing	leukocyte differentiation	The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.	got7fsn_ti	leucocyte differentiation|immune cell differentiation													biological_process											owl:Class	
GO:0042188	biolink:NamedThing	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.	got7fsn_ti	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane degradation|DDT catabolic process|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane breakdown|DDT catabolism|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolism													biological_process											owl:Class	
GO:0102764	biolink:NamedThing	6-deoxotyphasterol C-23 hydroxylase activity	Catalysis of the reaction: 6-deoxotyphasterol + O2 + a reduced electron acceptor = 6-deoxocastasterone + H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-777		molecular_function											owl:Class	
GO:0010647	biolink:NamedThing	positive regulation of cell communication	Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	got7fsn_ti														biological_process											owl:Class	
GO:0051215	biolink:NamedThing	RNAi-mediated antiviral immunity against DNA virus	Gene silencing induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing.  In plants, DCL3 is the primary Dicer to detect DNA viruses.	got7fsn_ti	DNA virus induced gene silencing|DNA VIGS|DNA virus-induced gene silencing	https://github.com/geneontology/go-ontology/issues/19958												biological_process											owl:Class	
GO:0035080	biolink:NamedThing	heat shock-mediated polytene chromosome puffing	The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:1990174	biolink:NamedThing	phosphodiesterase decapping endonuclease activity	Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA.	got7fsn_ti	G(5')pppN pyrophosphatase activity						tb	2013-08-26T17:51:00Z						molecular_function											owl:Class	
GO:0071853	biolink:NamedThing	fungal-type cell wall disassembly	A cellular process that results in the breakdown of a fungal-type cell wall.	got7fsn_ti							mah	2010-09-10T03:10:47Z						biological_process											owl:Class	
GO:0097514	biolink:NamedThing	sexual spore wall	A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.	got7fsn_ti							pr	2013-10-16T15:10:32Z						cellular_component											owl:Class	
GO:0099115	biolink:NamedThing	chromosome, subtelomeric region	A region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes. This region is usually heterochromatin.	got7fsn_ti	sub-telomeric heterochromatin|subtelomeric heterochromatin|subtelomere|nuclear subtelomeric heterochromatin	https://github.com/geneontology/go-ontology/issues/19086					vw	2014-07-18T13:32:59Z			GO:1990421|GO:1990707	SO:0001997		cellular_component											owl:Class	
GO:0008440	biolink:NamedThing	inositol-1,4,5-trisphosphate 3-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+).	got7fsn_ti	inositol-trisphosphate 3-kinase activity|IP3K activity|Ins(1,4,5)P3 3-kinase activity|1D-myo-inositol-trisphosphate 3-kinase activity|inositol trisphosphate 3-kinase activity|IP3 3-kinase activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase activity|ins(1,4,5)P(3) 3-kinase activity											Reactome:R-HSA-1855233|RHEA:11020|KEGG_REACTION:R03433|EC:2.7.1.127|MetaCyc:2.7.1.127-RXN|Reactome:R-HSA-1855153		molecular_function											owl:Class	
GO:0070721	biolink:NamedThing	ISGF3 complex	A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein.	got7fsn_ti	interferon-stimulated gene factor 3 transcription complex						mah	2009-06-10T05:22:05Z						cellular_component											owl:Class	
GO:0010286	biolink:NamedThing	heat acclimation	Any process that increases heat tolerance of an organism in response to high temperatures.	got7fsn_ti	thermotolerance													biological_process											owl:Class	
GO:0048484	biolink:NamedThing	enteric nervous system development	The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.	got7fsn_ti														biological_process											owl:Class	
GO:0090424	biolink:NamedThing	phytochelatin-metal-sulfur complex formation	A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex.	got7fsn_ti	HWM phytochelatin complex formation|high molecular weight phytochelatin complex formation						tb	2012-04-20T03:46:45Z						biological_process											owl:Class	
GO:0018181	biolink:NamedThing	peptidyl-arginine C5-methylation	The methylation of peptidyl-arginine on the carbon 5 (C5) residue to form peptidyl-5-methyl-L-arginine.	got7fsn_ti	peptidyl-arginine 5-methylation											RESID:AA0272		biological_process											owl:Class	
GO:0035245	biolink:NamedThing	peptidyl-arginine C-methylation	The addition of a methyl group onto a carbon atom of an arginine residue in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0018485	biolink:NamedThing	salicylaldehyde dehydrogenase activity	Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+.	got7fsn_ti	salicylaldehyde:NAD+ oxidoreductase activity											EC:1.2.1.65|MetaCyc:1.2.1.65-RXN|RHEA:18537|UM-BBD_enzymeID:e0256		molecular_function											owl:Class	
GO:0000454	biolink:NamedThing	snoRNA guided rRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.	got7fsn_ti														biological_process											owl:Class	
GO:0038138	biolink:NamedThing	ERBB4-ERBB4 signaling pathway	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	HER4-HER4 signaling pathway|ERBB4 homodimeric signaling pathway|ERBB4-ERBB4 signalling pathway						bf	2012-03-30T11:41:05Z						biological_process											owl:Class	
GO:1990622	biolink:NamedThing	CHOP-ATF3 complex	A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.	got7fsn_ti	CHOP-ATF3 heterodimeric complex|CHOP-ATF3 heterodimer|ATF3-CHOP complex|GADD153-ATF3 complex						bf	2015-01-29T16:43:19Z						cellular_component											owl:Class	
GO:0002247	biolink:NamedThing	clearance of damaged tissue involved in inflammatory response wound healing	The series of events leading to removal of necrotic debris that contribute to an inflammatory response.	got7fsn_ti	clearance of damaged tissue during inflammatory response													biological_process											owl:Class	
GO:0043791	biolink:NamedThing	dimethylamine methyltransferase activity	Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine.	got7fsn_ti	DMAMT 1|DMA methyltransferase 1|dimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|dimethylamine:corrinoid methyltransferase activity|mtbB1|MT1				This function is the first step in the pathway of methanogenesis from dimethylamine.							RHEA:41175|MetaCyc:RXN-8100|EC:2.1.1.249		molecular_function											owl:Class	
GO:0015478	biolink:NamedThing	oligosaccharide transporting porin activity	Enables the transfer of oligosaccharide, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	got7fsn_ti	raffinose porin													molecular_function											owl:Class	
GO:0015157	biolink:NamedThing	oligosaccharide transmembrane transporter activity	Enables the transfer of oligosaccharide from one side of a membrane to the other.	got7fsn_ti	endosomal oligosaccharide transporter													molecular_function											owl:Class	
GO:0046145	biolink:NamedThing	D-alanine family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of D-alanine and related amino acids.	got7fsn_ti	D-alanine family amino acid formation|D-alanine family amino acid synthesis|D-alanine family amino acid anabolism|D-alanine family amino acid biosynthesis													biological_process											owl:Class	
GO:0018019	biolink:NamedThing	N-terminal peptidyl-glutamine methylation	The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative.	got7fsn_ti												RESID:AA0071		biological_process											owl:Class	
GO:0010639	biolink:NamedThing	negative regulation of organelle organization	Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.	got7fsn_ti	negative regulation of organelle organisation|negative regulation of organelle organization and biogenesis													biological_process											owl:Class	
GO:0102044	biolink:NamedThing	3-chlorobenzoate-4,5-oxygenase activity	Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-10421		molecular_function											owl:Class	
GO:0047250	biolink:NamedThing	4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity	Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H(+) + UDP.	got7fsn_ti	UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid glucosyltransferase activity|HBA glucosyltransferase activity|PHB-O-glucosyltransferase activity|uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase activity|UDPglucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity|UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity|PHB glucosyltransferase activity|p-hydroxybenzoate glucosyltransferase activity											MetaCyc:2.4.1.194-RXN|KEGG_REACTION:R01304|EC:2.4.1.194|RHEA:15153		molecular_function											owl:Class	
GO:0016435	biolink:NamedThing	rRNA (guanine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.	got7fsn_ti														molecular_function											owl:Class	
GO:0047174	biolink:NamedThing	putrescine N-hydroxycinnamoyltransferase activity	Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+).	got7fsn_ti	putrescine hydroxycinnamoyl transferase activity|putrescine hydroxycinnamoyltransferase activity|caffeoyl-CoA:putrescine N-(3,4-dihydroxycinnamoyl)transferase activity|PHT|hydroxycinnamoyl-CoA:putrescine hydroxycinnamoyltransferase activity|caffeoyl-CoA putrescine N-caffeoyl transferase activity											EC:2.3.1.138|RHEA:12436|KEGG_REACTION:R01944|MetaCyc:2.3.1.138-RXN		molecular_function											owl:Class	
GO:0019534	biolink:NamedThing	toxin transmembrane transporter activity	Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.	got7fsn_ti														molecular_function											owl:Class	
GO:0006213	biolink:NamedThing	pyrimidine nucleoside metabolic process	The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	got7fsn_ti	pyrimidine nucleoside metabolism|pyrimidine metabolism|pyrimidine metabolic process													biological_process											owl:Class	
GO:0061177	biolink:NamedThing	type Is terminal bouton	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.	got7fsn_ti	type Is terminal button						dph	2010-07-13T09:25:15Z						cellular_component											owl:Class	
GO:0072089	biolink:NamedThing	stem cell proliferation	The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.	got7fsn_ti							mah	2010-02-08T02:03:36Z						biological_process											owl:Class	
GO:0036393	biolink:NamedThing	thiocyanate peroxidase activity	Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate.	got7fsn_ti	lactoperoxidase activity						bf	2013-06-20T16:03:57Z						molecular_function											owl:Class	
GO:0097187	biolink:NamedThing	dentinogenesis	The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.	got7fsn_ti	dentin development|dentine development						pr	2011-11-21T09:04:17Z						biological_process											owl:Class	
GO:0042475	biolink:NamedThing	odontogenesis of dentin-containing tooth	The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.	got7fsn_ti	tooth development|odontogeny|odontogenesis of dentine-containing teeth|odontogenesis of dentine-containing tooth|odontosis				Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales.									biological_process											owl:Class	
GO:0034930	biolink:NamedThing	1-hydroxypyrene sulfotransferase activity	Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX.	got7fsn_ti												UM-BBD_reactionID:r0952		molecular_function											owl:Class	
GO:0018619	biolink:NamedThing	benzene 1,2-dioxygenase activity	Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+).	got7fsn_ti	benzene dioxygenase activity|benzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)|benzene hydroxylase activity											KEGG_REACTION:R03543|MetaCyc:BENZENE-12-DIOXYGENASE-RXN|UM-BBD_reactionID:r0079|EC:1.14.12.3|RHEA:13813		molecular_function											owl:Class	
GO:0032613	biolink:NamedThing	interleukin-10 production	The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-10 biosynthetic process|IL-10 production|interleukin-10 secretion										GO:0072608|GO:0042091			biological_process											owl:Class	
GO:0004634	biolink:NamedThing	phosphopyruvate hydratase activity	Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.	got7fsn_ti	2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)|phosphoenolpyruvate hydratase activity|2-phosphoglycerate dehydratase activity|2-phosphoglycerate enolase activity|14-3-2-protein|nervous-system specific enolase|enolase activity|2-phospho-D-glycerate hydro-lyase activity|2-phosphoglyceric dehydratase activity|gamma-enolase activity|2-phospho-D-glycerate-hydrolase activity											RHEA:10164|EC:4.2.1.11|MetaCyc:2PGADEHYDRAT-RXN|Reactome:R-HSA-71660|Reactome:R-HSA-70494		molecular_function											owl:Class	
GO:0019346	biolink:NamedThing	transsulfuration	The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.	got7fsn_ti	transsulphuration|homocysteine-cysteine interconversion											MetaCyc:PWY-801|Wikipedia:Transsulfuration_pathway		biological_process											owl:Class	
GO:0050667	biolink:NamedThing	homocysteine metabolic process	The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.	got7fsn_ti	homocysteine metabolism|Hcy metabolism|Hcy metabolic process													biological_process											owl:Class	
GO:0004890	biolink:NamedThing	GABA-A receptor activity	Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.	got7fsn_ti	ionotropic GABA receptor activity				Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'chloride channel activity ; GO:0005254' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'.									molecular_function											owl:Class	
GO:0000410	biolink:NamedThing	carbon catabolite repression of transcription by galactose	A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.	got7fsn_ti	down-regulation of transcription by galactose|down regulation of transcription by galactose|inhibition of transcription by galactose|downregulation of transcription by galactose													biological_process											owl:Class	
GO:0042160	biolink:NamedThing	lipoprotein modification	The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	got7fsn_ti														biological_process											owl:Class	
GO:0007632	biolink:NamedThing	visual behavior	The behavior of an organism in response to a visual stimulus.	got7fsn_ti	behavioural response to visual stimulus|visual behaviour|behavioral response to visual stimulus													biological_process											owl:Class	
GO:0051933	biolink:NamedThing	amino acid neurotransmitter reuptake	The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	got7fsn_ti	amino acid neurotransmitter recycling|amino acid uptake during transmission of nerve impulse|amino acid neurotransmitter import into glial cell|amino acid neurotransmitter import into neuron													biological_process											owl:Class	
GO:0103005	biolink:NamedThing	9,10-epoxystearate hydrolase activity	Catalysis of the reaction: 9,10-epoxystearate + H2O <=> (9R,10S)-dihydroxystearate.	got7fsn_ti												MetaCyc:RXN-9806		molecular_function											owl:Class	
GO:0003288	biolink:NamedThing	ventricular septum intermedium morphogenesis	The developmental process in which a ventricular septum intermedium is generated and organized.	got7fsn_ti							dph	2009-10-20T10:58:48Z						biological_process											owl:Class	
GO:0046334	biolink:NamedThing	octopamine catabolic process	The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.	got7fsn_ti	octopamine degradation|octopamine breakdown|octopamine catabolism													biological_process											owl:Class	
GO:0075210	biolink:NamedThing	suppression by symbiont of host cAMP-mediated signal transduction	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host cAMP-mediated signaling|negative regulation by symbiont of host cAMP-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "Negative regulation by host of symbiont cAMP-mediated signal transduction ; GO:0075207".									biological_process											owl:Class	
GO:0051921	biolink:NamedThing	adenosylcobyric acid synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H(2)O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H(+) + 4 phosphate.	got7fsn_ti	5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase activity|cobyric acid synthase activity|Ado-cobyric acid synthase [glutamine hydrolyzing] activity|adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase (ADP-forming)|adenosylcobyric acid synthase (glutamine-hydrolysing) activity|CobQ activity											KEGG_REACTION:R05225|EC:6.3.5.10|MetaCyc:R345-RXN|RHEA:23256		molecular_function											owl:Class	
GO:0102902	biolink:NamedThing	isopimaradienal hydroxylase activity	Catalysis of the reaction: isopimaradienal + NADPH + O2 <=> isopimaric acid + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-8538		molecular_function											owl:Class	
GO:0048903	biolink:NamedThing	anterior lateral line neuromast hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0043152	biolink:NamedThing	induction of bacterial agglutination	Any process in which infecting bacteria are clumped together by a host organism.	got7fsn_ti														biological_process											owl:Class	
GO:0019731	biolink:NamedThing	antibacterial humoral response	An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.	got7fsn_ti											GO:0019733|GO:0006961			biological_process											owl:Class	
GO:0001068	biolink:NamedThing	transcription regulatory region RNA binding	Binding to a RNA region within the transcript that regulates the transcription of a gene, cistron, or operon.	got7fsn_ti							krc	2010-10-21T04:15:32Z						molecular_function											owl:Class	
GO:0103043	biolink:NamedThing	5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase activity	Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> H+ + alpha-D-ribose 1,5-bisphosphate.	got7fsn_ti												EC:3.1.4.55|RHEA:34795|MetaCyc:RXN0-6710		molecular_function											owl:Class	
GO:0001964	biolink:NamedThing	startle response	An action or movement due to the application of a sudden unexpected stimulus.	got7fsn_ti												Wikipedia:Startle_reaction		biological_process											owl:Class	
GO:0052651	biolink:NamedThing	monoacylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.	got7fsn_ti	monoacylglycerol breakdown|monoacylglycerol catabolism|monoacylglycerol degradation							2010-09-23T09:26:36Z						biological_process											owl:Class	
GO:0047702	biolink:NamedThing	beta-lysine 5,6-aminomutase activity	Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate.	got7fsn_ti	b-lysine 5,6-aminomutase activity|L-beta-lysine 5,6-aminomutase activity|beta-lysine mutase activity|(3S)-3,6-diaminohexanoate 5,6-aminomutase activity											EC:5.4.3.3|MetaCyc:BETA-LYSINE-56-AMINOMUTASE-RXN|RHEA:21736|KEGG_REACTION:R03275		molecular_function											owl:Class	
GO:0103047	biolink:NamedThing	methyl beta-D-glucoside 6-phosphate glucohydrolase activity	Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol.	got7fsn_ti												EC:3.2.1.86|MetaCyc:RXN0-6994		molecular_function											owl:Class	
GO:0034017	biolink:NamedThing	trans-2-decenoyl-acyl-carrier-protein isomerase activity	Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].	got7fsn_ti	trans-2-decenoyl-ACP isomerase activity|trans-2-cis-3-decenoyl-ACP isomerase activity|beta-hydroxydecanoyl thioester dehydrase activity|trans-2, cis-3 decenoyl-ACP isomerase activity|decenoyl-acyl-carrier-protein delta2-trans-delta3-cis-isomerase activity|trans-2, cis-3 decenoyl-[acyl-carrier-protein] isomerase activity|trans-2,cis-3-decenoyl-ACP isomerase activity|FabM										GO:0043832	RHEA:23568|EC:5.3.3.14|MetaCyc:5.3.3.14-RXN		molecular_function											owl:Class	
GO:0004667	biolink:NamedThing	prostaglandin-D synthase activity	Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).	got7fsn_ti	(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity|prostaglandin-R-prostaglandin D isomerase activity|prostaglandin-H2 D-isomerase activity|PGH-PGD isomerase activity|prostaglandin D2 synthase activity|PGD2 synthase activity											RHEA:10600|EC:5.3.99.2|MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN|KEGG_REACTION:R02266|Reactome:R-HSA-2161620|Reactome:R-HSA-2161701		molecular_function											owl:Class	
GO:0038061	biolink:NamedThing	NIK/NF-kappaB signaling	The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52).	got7fsn_ti	NIK/NF-kappaB signal transduction|noncanonical nuclear factor kappaB (NF-kappaB) pathway|noncanonical NF-kappaB signaling|p52-dependent NF-kappaB signaling|NIK/NF-kappaB cascade|non-canonical NF-KB signaling						bf	2012-01-16T05:44:46Z						biological_process											owl:Class	
GO:0097371	biolink:NamedThing	MDM2/MDM4 family protein binding	Binding to a member of the MDM2/MDM4 protein family, comprising negative regulators of p53.	got7fsn_ti							pr	2012-08-08T16:20:59Z						molecular_function											owl:Class	
GO:1990893	biolink:NamedThing	mitotic chromosome centromere condensation	The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis.	got7fsn_ti	mitotic chromosome condensation at kinetochore						vw	2015-11-03T14:26:29Z						biological_process											owl:Class	
GO:1901143	biolink:NamedThing	insulin catabolic process	The chemical reactions and pathways resulting in the breakdown of insulin.	got7fsn_ti	insulin catabolism|insulin breakdown|insulin degradation						pm	2012-07-13T12:33:03Z						biological_process											owl:Class	
GO:1901142	biolink:NamedThing	insulin metabolic process	The chemical reactions and pathways involving insulin.	got7fsn_ti	insulin metabolism						pm	2012-07-13T12:32:40Z						biological_process											owl:Class	
GO:0050137	biolink:NamedThing	NADPH peroxidase activity	Catalysis of the reaction: H(2)O(2) + H(+) + NADPH = 2 H(2)O + NADP(+).	got7fsn_ti	NADPH:hydrogen-peroxide oxidoreductase activity|TPN peroxidase activity|TPNH peroxidase activity|nicotinamide adenine dinucleotide phosphate peroxidase activity|NADP peroxidase activity|triphosphopyridine nucleotide peroxidase activity											RHEA:15173|KEGG_REACTION:R00113|MetaCyc:NADPH-PEROXIDASE-RXN|EC:1.11.1.2		molecular_function											owl:Class	
GO:0034736	biolink:NamedThing	cholesterol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.	got7fsn_ti	acyl coenzyme A-cholesterol-O-acyltransferase activity|cholesterol acyltransferase activity|acyl-CoA:cholesterol acyltransferase activity|acylcoenzyme A:cholesterol O-acyltransferase activity|cholesterol ester synthetase activity|ACAT activity|acyl-CoA:cholesterol O-acyltransferase activity|cholesteryl ester synthetase activity											EC:2.3.1.26|KEGG_REACTION:R01461|MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN|Reactome:R-HSA-8876696|RHEA:17729		molecular_function											owl:Class	
GO:0004772	biolink:NamedThing	sterol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester.	got7fsn_ti	sterol-ester synthase activity|sterol-ester synthetase activity										GO:0017066			molecular_function											owl:Class	
GO:0030378	biolink:NamedThing	serine racemase activity	Catalysis of the synthesis of free D-serine from L-serine.	got7fsn_ti												Reactome:R-HSA-9014766|RHEA:10980|MetaCyc:5.1.1.18-RXN|EC:5.1.1.18		molecular_function											owl:Class	
GO:0097376	biolink:NamedThing	interneuron axon guidance	The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.	got7fsn_ti							pr	2012-10-01T10:18:35Z						biological_process											owl:Class	
GO:0002402	biolink:NamedThing	B cell tolerance induction in mucosal-associated lymphoid tissue	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.	got7fsn_ti	B cell tolerance induction in MALT													biological_process											owl:Class	
GO:0070136	biolink:NamedThing	beta-1,2-oligomannoside biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.	got7fsn_ti	beta-1,2-oligomannoside biosynthesis|beta-1,2-oligomannoside formation|beta-1,2-oligomannoside synthesis|beta-1,2-oligomannoside anabolism													biological_process											owl:Class	
GO:0016690	biolink:NamedThing	diarylpropane peroxidase activity	Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O.	got7fsn_ti	diarylpropane oxygenase activity|diarylpropane:oxygen,hydrogen-peroxide oxidoreductase (C-C-bond-cleaving)|lignin peroxidase activity|1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol:hydrogen-peroxide oxidoreductase activity|ligninase activity|ligninase I activity|LiP activity											EC:1.11.1.14|RHEA:30271|MetaCyc:DIARYLPROPANE-PEROXIDASE-RXN		molecular_function											owl:Class	
GO:0001853	biolink:NamedThing	complement component C3dg binding	Binding to a C3dg product of the complement cascade.	got7fsn_ti														molecular_function											owl:Class	
GO:0043817	biolink:NamedThing	phosphosulfolactate synthase activity	Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite.	got7fsn_ti	PSL synthase activity|(2R)-O-phospho-3-sulfolactate sulfo-lyase (phosphoenolpyruvate-forming)|(2R)-O-phospho-3-sulfolactate sulfo-lyase activity|(2R)-phospho-3-sulfolactate synthase activity											MetaCyc:4.4.1.19-RXN|KEGG_REACTION:R07476|EC:4.4.1.19|RHEA:22784|MetaCyc:R228-RXN		molecular_function											owl:Class	
GO:0039663	biolink:NamedThing	membrane fusion involved in viral entry into host cell	Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell.	got7fsn_ti	fusion of virus membrane with host membrane|fusion of virus membrane with host membrane during viral entry|viral entry into host cell via membrane fusion						bf	2013-08-29T10:15:11Z						biological_process											owl:Class	
GO:0042410	biolink:NamedThing	6-carboxyhexanoate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H(+) + pimelyl-CoA.	got7fsn_ti	6-carboxyhexanoate:CoA ligase (AMP-forming)|pimeloyl-CoA synthetase activity|pimelyl-CoA synthetase activity|6-carboxyhexanoyl-CoA synthetase activity											MetaCyc:6-CARBOXYHEXANOATE--COA-LIGASE-RXN|RHEA:14781|KEGG_REACTION:R03209|EC:6.2.1.14		molecular_function											owl:Class	
GO:0004185	biolink:NamedThing	serine-type carboxypeptidase activity	Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	got7fsn_ti	serine carboxypeptidase activity	https://github.com/geneontology/go-ontology/issues/19681										MetaCyc:3.4.16.5-RXN|EC:3.4.16.5|EC:3.4.16.6|MetaCyc:3.4.16.6-RXN|Reactome:R-HSA-158251|EC:3.4.16.-|EC:3.4.16.2|MetaCyc:3.4.16.2-RXN		molecular_function											owl:Class	
GO:0030184	biolink:NamedThing	nitric oxide transmembrane transporter activity	Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0004528	biolink:NamedThing	phosphodiesterase I activity	Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.	got7fsn_ti	5'-nucleotide phosphodiesterase activity|5'-phosphodiesterase activity|5'-exonuclease activity|PDE I activity|5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|oligonucleate 5'-nucleotidohydrolase activity|5'-PDE activity|5'-NPDase activity|exonuclease I activity|alkaline phosphodiesterase activity|5'-PDase activity|orthophosphoric diester phosphohydrolase activity|5'NPDE activity|phosphodiesterase activity|nucleotide pyrophosphatase/phosphodiesterase I activity											MetaCyc:3.1.4.1-RXN|EC:3.1.4.1		molecular_function											owl:Class	
GO:0043154	biolink:NamedThing	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.	got7fsn_ti	downregulation of caspase activity|negative regulation of caspase activation|down-regulation of caspase activity|inhibition of caspase activity|negative regulation of caspase activity|inhibition of caspase activation|down regulation of caspase activity										GO:0001719			biological_process											owl:Class	
GO:0000421	biolink:NamedThing	autophagosome membrane	The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.	got7fsn_ti	autophagic vacuole membrane													cellular_component											owl:Class	
GO:0005774	biolink:NamedThing	vacuolar membrane	The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:2001152	biolink:NamedThing	negative regulation of renal water transport	Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport.	got7fsn_ti							yaf	2011-10-24T11:37:57Z						biological_process											owl:Class	
GO:0102511	biolink:NamedThing	pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+.	got7fsn_ti												EC:2.4.1.300|MetaCyc:RXN-14440		molecular_function											owl:Class	
GO:0035647	biolink:NamedThing	3-oxo-delta(4,5)-steroid 5-beta-reductase activity	Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+).	got7fsn_ti	3-oxo-delta4,5-steroid 5beta-reductase						bf	2011-01-24T01:31:30Z						molecular_function											owl:Class	
GO:0016203	biolink:NamedThing	muscle attachment	The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).	got7fsn_ti														biological_process											owl:Class	
GO:0050330	biolink:NamedThing	theanine hydrolase activity	Catalysis of the reaction: N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine.	got7fsn_ti	N5-ethyl-L-glutamine amidohydrolase activity|5-N-ethyl-L-glutamine amidohydrolase activity|L-theanine amidohydrolase activity											KEGG_REACTION:R02930|RHEA:18013|MetaCyc:THEANINE-HYDROLASE-RXN|EC:3.5.1.65		molecular_function											owl:Class	
GO:0008863	biolink:NamedThing	formate dehydrogenase (NAD+) activity	Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH.	got7fsn_ti	N-FDH|formate:NAD+ oxidoreductase|NAD-dependent formate dehydrogenase|formate dehydrogenase (NAD)|formic hydrogen-lyase|formic acid dehydrogenase|FDH II|NAD-formate dehydrogenase|formate hydrogenlyase|NAD-linked formate dehydrogenase|formate benzyl-viologen oxidoreductase|formate-NAD oxidoreductase|FDH I										GO:0018476	EC:1.17.1.9|UM-BBD_reactionID:r0103|MetaCyc:FORMATEDEHYDROG-RXN|KEGG_REACTION:R00519|MetaCyc:1.2.1.2-RXN|RHEA:15985		molecular_function											owl:Class	
GO:0043895	biolink:NamedThing	cyclomaltodextrin glucanotransferase activity	Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond.	got7fsn_ti	cyclomaltodextrin glucotransferase|cyclomaltodextrin glycosyltransferase|beta-cyclodextrin glucanotransferase|BMA|gamma-cyclodextrin glycosyltransferase|alpha-cyclodextrin glucanotransferase|1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing)|konchizaimu|neutral-cyclodextrin glycosyltransferase|CGTase|beta-cyclodextrin glycosyltransferase|alpha-1,4-glucan 4-glycosyltransferase, cyclizing|cyclodextrin glucanotransferase|Bacillus macerans amylase|cyclodextrin glycosyltransferase|alpha-cyclodextrin glycosyltransferase											MetaCyc:2.4.1.19-RXN|EC:2.4.1.19		molecular_function											owl:Class	
GO:0055077	biolink:NamedThing	gap junction hemi-channel activity	A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction.	got7fsn_ti	connexon channel activity													molecular_function											owl:Class	
GO:0004780	biolink:NamedThing	sulfate adenylyltransferase (ADP) activity	Catalysis of the reaction: ADP + H(+) + sulfate = 5'-adenylyl sulfate + phosphate.	got7fsn_ti	ADP:sulfate adenylyltransferase activity|sulphate adenylyltransferase (ADP) activity|ADP-sulfurylase activity|sulfate (adenosine diphosphate) adenylyltransferase activity|adenosine diphosphate sulfurylase activity											RHEA:16529|KEGG_REACTION:R00530|EC:2.7.7.5|MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN		molecular_function											owl:Class	
GO:0030779	biolink:NamedThing	10-hydroxydihydrosanguinarine 10-O-methyltransferase activity	Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase activity											EC:2.1.1.119|RHEA:18541|MetaCyc:2.1.1.119-RXN|KEGG_REACTION:R04707		molecular_function											owl:Class	
GO:0052094	biolink:NamedThing	formation of haustorium for nutrient acquisition	The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	formation by organism of haustorium for nutrient acquisition from host|formation by organism of haustoria for nutrient acquisition from host|formation by symbiont of haustorium for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305												biological_process											owl:Class	
GO:0102416	biolink:NamedThing	quercetin gentiotrioside 1,6-glucosyltransferase activity	Catalysis of the reaction: quercetin-3-gentiotrioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotetraside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13799		molecular_function											owl:Class	
GO:0033067	biolink:NamedThing	macrolide metabolic process	The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.	got7fsn_ti	macrolide metabolism													biological_process											owl:Class	
GO:0070858	biolink:NamedThing	negative regulation of bile acid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.	got7fsn_ti	inhibition of bile acid biosynthetic process|down regulation of bile acid biosynthetic process|negative regulation of bile acid biosynthesis|downregulation of bile acid biosynthetic process|negative regulation of bile acid formation|down-regulation of bile acid biosynthetic process|negative regulation of bile acid synthesis|negative regulation of bile acid anabolism						mah	2009-08-14T03:16:40Z						biological_process											owl:Class	
GO:0097016	biolink:NamedThing	L27 domain binding	Binding to a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.	got7fsn_ti							pr	2011-03-23T02:17:51Z						molecular_function											owl:Class	
GO:0001594	biolink:NamedThing	trace-amine receptor activity	Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.	got7fsn_ti														molecular_function											owl:Class	
GO:0002048	biolink:NamedThing	pyoverdine metabolic process	The chemical reactions and pathways involving the siderochrome pyoverdine.	got7fsn_ti	pyoverdine metabolism													biological_process											owl:Class	
GO:0062202	biolink:NamedThing	Labd-13(16),14-diene-9-ol synthase activity	Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol.	got7fsn_ti							dph	2020-01-02T15:46:00Z				RHEA:62184		molecular_function											owl:Class	
GO:2000933	biolink:NamedThing	regulation of cellotriose metabolic process	Any process that modulates the frequency, rate or extent of cellotriose metabolic process.	got7fsn_ti	regulation of cellotriose metabolism						tt	2011-08-01T12:44:15Z						biological_process											owl:Class	
GO:0034280	biolink:NamedThing	ent-sandaracopimaradiene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate.	got7fsn_ti	ent-copalyl-diphosphate diphosphate-lyase [ent-sandaracopimara-8(14),15-diene-forming] activity|ent-pimaradiene synthase activity											MetaCyc:RXN-4884|RHEA:25536|EC:4.2.3.29|KEGG_REACTION:R09120		molecular_function											owl:Class	
GO:0033463	biolink:NamedThing	GGA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GGA codon.	got7fsn_ti	glycine tRNA				Note that in the standard genetic code, GGA codes for glycine.									molecular_function											owl:Class	
GO:0034723	biolink:NamedThing	DNA replication-dependent nucleosome organization	The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation.	got7fsn_ti	DNA replication-dependent nucleosome organisation													biological_process											owl:Class	
GO:0019617	biolink:NamedThing	protocatechuate catabolic process, meta-cleavage	The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate.	got7fsn_ti	protocatechuate catabolic process to oxaloacetate and pyruvate|3,4-dihydroxybenzoate catabolic process, meta-cleavage|protocatechuate degradation, meta-cleavage|protocatechuate breakdown, meta-cleavage											MetaCyc:P184-PWY		biological_process											owl:Class	
GO:0097670	biolink:NamedThing	SCF-Ufo1/Pof10 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe).	got7fsn_ti							pr	2014-10-06T10:29:13Z						cellular_component											owl:Class	
GO:1990026	biolink:NamedThing	hippocampal mossy fiber expansion	Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites.	got7fsn_ti	dentate gyrus mossy fiber expansion|dentate gyrus granule cell axonal bouton|mossy fiber expansion						pr	2013-02-06T10:31:59Z				NIF_Subcellular:nlx_subcell_1005002		cellular_component											owl:Class	
GO:0016508	biolink:NamedThing	long-chain-enoyl-CoA hydratase activity	Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms.	got7fsn_ti	long-chain enoyl coenzyme A hydratase activity|long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase activity											Reactome:R-HSA-2066778|Reactome:R-HSA-390252|MetaCyc:LONG-CHAIN-ENOYL-COA-HYDRATASE-RXN|EC:4.2.1.74|Reactome:R-HSA-2066780|Reactome:R-HSA-389986|Reactome:R-HSA-6809263		molecular_function											owl:Class	
GO:0009779	biolink:NamedThing	noncyclic photosynthetic phosphorylation	A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II.	got7fsn_ti														biological_process											owl:Class	
GO:0031947	biolink:NamedThing	negative regulation of glucocorticoid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.	got7fsn_ti	inhibition of glucocorticoid biosynthetic process|downregulation of glucocorticoid biosynthetic process|down-regulation of glucocorticoid biosynthetic process|down regulation of glucocorticoid biosynthetic process													biological_process											owl:Class	
GO:0052162	biolink:NamedThing	modulation by symbiont of defense-related host calcium ion flux	Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction|modulation by organism of defense-related host Ca2+ flux										GO:0052301			biological_process											owl:Class	
GO:0001939	biolink:NamedThing	female pronucleus	The pronucleus originating from the ovum that is being fertilized.	got7fsn_ti														cellular_component											owl:Class	
GO:0061337	biolink:NamedThing	cardiac conduction	Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.	got7fsn_ti							dph	2010-09-29T08:46:05Z						biological_process											owl:Class	
GO:1990410	biolink:NamedThing	adrenomedullin receptor signaling pathway	A series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell.	got7fsn_ti	AM receptor signaling pathway				An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.		bhm	2014-07-02T14:43:31Z						biological_process											owl:Class	
GO:0090246	biolink:NamedThing	convergent extension involved in somitogenesis	The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.	got7fsn_ti							tb	2010-01-22T10:59:06Z						biological_process											owl:Class	
GO:0070221	biolink:NamedThing	sulfide oxidation, using sulfide:quinone oxidoreductase	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.	got7fsn_ti	sulfide oxidation, using sulfide-quinone reductase|sulphide oxidation, using sulfide:quinone oxidoreductase											MetaCyc:P222-PWY		biological_process											owl:Class	
GO:0019418	biolink:NamedThing	sulfide oxidation	The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate.	got7fsn_ti	sulphide oxidation											MetaCyc:P222-PWY		biological_process											owl:Class	
GO:0006301	biolink:NamedThing	postreplication repair	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.	got7fsn_ti	postreplication DNA repair											Wikipedia:Postreplication_repair		biological_process											owl:Class	
GO:0035912	biolink:NamedThing	dorsal aorta morphogenesis	The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.	got7fsn_ti							bf	2011-06-24T11:22:14Z						biological_process											owl:Class	
GO:0102076	biolink:NamedThing	beta,beta-carotene-9',10'-cleaving oxygenase activity	Catalysis of the reaction: beta-carotene + O2 <=> 10'-apo-beta-carotenal + beta-ionone.	got7fsn_ti												RHEA:26389|EC:1.13.11.71|MetaCyc:RXN-10741		molecular_function											owl:Class	
GO:0034594	biolink:NamedThing	phosphatidylinositol trisphosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0050340	biolink:NamedThing	thymidylate 5'-phosphatase activity	Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate.	got7fsn_ti	dTMPase activity|thymidylate 5'-phosphohydrolase activity|thymidylate 5' phosphatase activity|thymidylate 5'-nucleotidase activity|deoxythymidylic 5'-nucleotidase activity|deoxythymidylate 5'-nucleotidase activity|thymidylate nucleotidase activity|deoxythymidylate phosphohydrolase activity											EC:3.1.3.35|MetaCyc:THYMIDYLATE-5-PHOSPHATASE-RXN|RHEA:11080		molecular_function											owl:Class	
GO:0061259	biolink:NamedThing	mesonephric glomerular mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.	got7fsn_ti							dph	2010-08-30T02:22:45Z						biological_process											owl:Class	
GO:0060290	biolink:NamedThing	transdifferentiation	The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.	got7fsn_ti												Wikipedia:Transdifferentiation		biological_process											owl:Class	
GO:0106177	biolink:NamedThing	cyclic-GMP-AMP hydrolase activity	Catalysis of the reaction: cyclic GMP-AMP + 2 H2O = AMP + GMP.	got7fsn_ti							hjd	2019-03-07T21:06:24Z				RHEA:58808		molecular_function											owl:Class	
GO:0019520	biolink:NamedThing	aldonic acid metabolic process	The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.	got7fsn_ti	aldonic acid metabolism													biological_process											owl:Class	
GO:0006524	biolink:NamedThing	alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid.	got7fsn_ti	alanine degradation|alanine catabolism|alanine breakdown													biological_process											owl:Class	
GO:0044716	biolink:NamedThing	8-oxo-GDP phosphatase activity	Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.	got7fsn_ti							jl	2012-10-18T13:32:39Z				EC:3.6.1.58|RHEA:62356		molecular_function											owl:Class	
GO:0072525	biolink:NamedThing	pyridine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.	got7fsn_ti	pyridine and derivative biosynthetic process|pyridine-containing compound synthesis|pyridine-containing compound formation|pyridine-containing compound biosynthesis|pyridine-containing compound anabolism						mah	2011-01-04T03:23:01Z						biological_process											owl:Class	
GO:0033679	biolink:NamedThing	3'-5' DNA/RNA helicase activity	Unwinding of a DNA/RNA duplex in the 3' to 5' direction, driven by ATP hydrolysis.	got7fsn_ti	3' to 5' DNA/RNA helicase activity|ATP-dependent 3' to 5' DNA/RNA helicase activity|ATP-dependent 3'-5' DNA/RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612									GO:0033681			molecular_function											owl:Class	
GO:0102878	biolink:NamedThing	(+)-alpha-barbatene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-alpha-barbatene + diphosphoric acid.	got7fsn_ti												EC:4.2.3.69|MetaCyc:RXN-8417|RHEA:29499		molecular_function											owl:Class	
GO:0006809	biolink:NamedThing	nitric oxide biosynthetic process	The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	got7fsn_ti	nitric oxide synthesis|nitric oxide biosynthesis|nitric oxide anabolism|nitric oxide formation													biological_process											owl:Class	
GO:0035178	biolink:NamedThing	turning behavior	Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source.	got7fsn_ti	turning behaviour													biological_process											owl:Class	
GO:0006958	biolink:NamedThing	complement activation, classical pathway	Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.	got7fsn_ti	complement cascade, classical pathway													biological_process											owl:Class	
GO:0045925	biolink:NamedThing	positive regulation of female receptivity	Any process that activates or increases the receptiveness of a female to male advances.	got7fsn_ti	upregulation of female receptivity|up-regulation of female receptivity|activation of female receptivity|stimulation of female receptivity|up regulation of female receptivity													biological_process											owl:Class	
GO:0048922	biolink:NamedThing	posterior lateral line neuromast deposition	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.	got7fsn_ti														biological_process											owl:Class	
GO:0048885	biolink:NamedThing	neuromast deposition	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line.	got7fsn_ti														biological_process											owl:Class	
GO:0003974	biolink:NamedThing	UDP-N-acetylglucosamine 4-epimerase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.	got7fsn_ti	UDP-GlcNAc 4-epimerase activity|uridine diphosphoacetylglucosamine epimerase activity|UDP acetylglucosamine epimerase activity|uridine 5'-diphospho-N-acetylglucosamine-4-epimerase activity|uridine diphosphate N-acetylglucosamine-4-epimerase activity|UDP-N-acetyl-D-glucosamine 4-epimerase activity											RHEA:20517|EC:5.1.3.7|MetaCyc:UDP-N-ACETYLGLUCOSAMINE-4-EPIMERASE-RXN		molecular_function											owl:Class	
GO:0030631	biolink:NamedThing	pyrrolysine incorporation	The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases.	got7fsn_ti	lysine methylamine methyltransferase cofactor adduct incorporation|monomethylamine methyltransferase cofactor lysine adduct incorporation											RESID:AA0321		biological_process											owl:Class	
GO:0006451	biolink:NamedThing	translational readthrough	The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.	got7fsn_ti	natural nonsense suppression													biological_process											owl:Class	
GO:0044511	biolink:NamedThing	envenomation resulting in modulation of receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism.	got7fsn_ti							jl	2012-02-26T10:12:24Z						biological_process											owl:Class	
GO:0007291	biolink:NamedThing	sperm individualization	The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0039622	biolink:NamedThing	T=16 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres.	got7fsn_ti							bf	2012-07-18T02:20:23Z				VZ:807		cellular_component											owl:Class	
GO:0106373	biolink:NamedThing	3-deoxyglucosone dehydrogenase activity	Catalysis of the reaction: 3-deoxyglucosone + H2O + NAD(+) = 2-dehydro-3-deoxy-D-gluconate + 2 H(+) + NADH.	got7fsn_ti							hjd	2021-04-12T14:48:12Z						molecular_function											owl:Class	
GO:0048308	biolink:NamedThing	organelle inheritance	The partitioning of organelles between daughter cells at cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0061574	biolink:NamedThing	ASAP complex	A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.	got7fsn_ti							dph	2013-10-08T13:09:16Z						cellular_component											owl:Class	
GO:0097123	biolink:NamedThing	cyclin A1-CDK2 complex	A protein complex consisting of cyclin A1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:43:18Z						cellular_component											owl:Class	
GO:0032628	biolink:NamedThing	interleukin-24 production	The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	MDA7 production|ST16 production|IL-24 production|interleukin-24 secretion|interleukin-24 biosynthetic process										GO:0072622|GO:0045524			biological_process											owl:Class	
GO:0090687	biolink:NamedThing	activation of meiosis I spindle assembly checkpoint	Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint.	got7fsn_ti							tb	2016-07-20T16:49:17Z						biological_process											owl:Class	
GO:1905326	biolink:NamedThing	positive regulation of meiosis I spindle assembly checkpoint	Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint.	got7fsn_ti	upregulation of meiosis I spindle assembly checkpoint|up regulation of meiosis I spindle assembly checkpoint|activation of meiosis I spindle assembly checkpoint|up-regulation of meiosis I spindle assembly checkpoint						mah	2016-07-20T12:48:47Z						biological_process											owl:Class	
GO:0070095	biolink:NamedThing	fructose-6-phosphate binding	Binding to fructose 6-phosphate.	got7fsn_ti	fructose 6-phosphate binding|D-fructose 6-phosphate binding													molecular_function											owl:Class	
GO:0005729	biolink:NamedThing	2-micrometer circle DNA	A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies.	got7fsn_ti														cellular_component											owl:Class	
GO:0005727	biolink:NamedThing	extrachromosomal circular DNA	Circular DNA structures that are not part of a chromosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0102966	biolink:NamedThing	arachidoyl-CoA:1-dodecanol O-acyltransferase activity	Catalysis of the reaction: icosanoyl-CoA + dodecan-1-ol = arachidoyl dodecanoate + coenzyme A.	got7fsn_ti												EC:2.3.1.75|MetaCyc:RXN-9356		molecular_function											owl:Class	
GO:0010586	biolink:NamedThing	miRNA metabolic process	The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.	got7fsn_ti	microRNA metabolic process													biological_process											owl:Class	
GO:0051258	biolink:NamedThing	protein polymerization	The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.	got7fsn_ti	protein polymer biosynthetic process|protein polymer biosynthesis|protein polymer formation													biological_process											owl:Class	
GO:0140288	biolink:NamedThing	GBAF complex	A SWI/SNF subcomplex that incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM.	got7fsn_ti							pg	2018-11-20T09:13:52Z						cellular_component											owl:Class	
GO:0106336	biolink:NamedThing	yolk syncytial layer development	The progression of the yolk syncytial layer over time, from its initial formation to the mature structure. The yolk syncytial layer is the peripheral layer of the yolk cell including nuclei and non-yolky cytoplasm.	got7fsn_ti	YSL development				The "yolk syncytial layer" structure can be found in Teleostei, Myxini, Chondrichthyes, Lepisosteiformes and Cephalopoda according.		hjd	2020-11-05T17:56:43Z						biological_process											owl:Class	
GO:0035850	biolink:NamedThing	epithelial cell differentiation involved in kidney development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state.	got7fsn_ti							bf	2011-05-11T11:34:21Z						biological_process											owl:Class	
GO:0002270	biolink:NamedThing	plasmacytoid dendritic cell activation	A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	got7fsn_ti														biological_process											owl:Class	
GO:0004663	biolink:NamedThing	Rab geranylgeranyltransferase activity	Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.	got7fsn_ti	GGTase-II activity|protein geranylgeranyltransferase type II activity|type II protein geranyl-geranyltransferase activity|geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity|GGTaseII activity|RabGGTase activity|Rab-protein geranylgeranyltransferase activity											MetaCyc:2.5.1.60-RXN|MetaCyc:RXN-3701|EC:2.5.1.60		molecular_function											owl:Class	
GO:0034413	biolink:NamedThing	ascospore wall (1->3)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.	got7fsn_ti	ascospore wall beta-1,3-glucan formation|ascospore wall beta-1,3-glucan synthesis|ascospore wall beta-1,3-glucan anabolism|ascospore wall beta-1,3-glucan biosynthesis|ascospore wall 1,3-beta-glucan formation|ascospore wall 1,3-beta-glucan biosynthesis|ascospore wall 1,3-beta-glucan biosynthetic process|ascospore wall 1,3-beta-D-glucan biosynthetic process|ascospore wall 1,3-beta-glucan synthesis|ascospore wall beta-1,3-glucan biosynthetic process|ascospore wall 1,3-beta-glucan anabolism													biological_process											owl:Class	
GO:0071970	biolink:NamedThing	fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls.	got7fsn_ti	fungal-type cell wall beta-1,3-glucan formation|fungal-type cell wall 1,3-beta-glucan biosynthesis|fungal-type cell wall 1,3-beta-glucan formation|fungal-type cell wall beta-1,3-glucan synthesis|fungal-type cell wall 1,3-beta-glucan anabolism|fungal-type cell wall beta-1,3-glucan anabolism|fungal-type cell wall 1,3-beta-D-glucan biosynthetic process|fungal-type cell wall beta-1,3-glucan biosynthesis|fungal-type cell wall beta-1,3-glucan biosynthetic process|fungal-type cell wall 1,3-beta-glucan synthesis						mah	2010-10-18T03:25:56Z						biological_process											owl:Class	
GO:0036457	biolink:NamedThing	keratohyalin granule	A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope.	got7fsn_ti							bf	2013-12-09T13:04:09Z						cellular_component											owl:Class	
GO:0097534	biolink:NamedThing	lymphoid lineage cell migration	The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage.	got7fsn_ti	lymphoid lineage restricted progenitor cell migration						pr	2013-11-28T10:47:15Z						biological_process											owl:Class	
GO:0003135	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in heart induction	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to heart induction.	got7fsn_ti	fibroblast growth factor receptor signalling pathway involved in heart induction						tb	2009-09-22T03:17:49Z						biological_process											owl:Class	
GO:0072524	biolink:NamedThing	pyridine-containing compound metabolic process	The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.	got7fsn_ti	pyridine and derivative metabolic process|pyridine-containing compound metabolism						mah	2011-01-04T03:21:47Z						biological_process											owl:Class	
GO:0031536	biolink:NamedThing	positive regulation of exit from mitosis	Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).	got7fsn_ti	upregulation of exit from mitosis|up regulation of exit from mitosis|activation of exit from mitosis|up-regulation of exit from mitosis|stimulation of exit from mitosis													biological_process											owl:Class	
GO:0047202	biolink:NamedThing	sinapoylglucose-choline O-sinapoyltransferase activity	Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose.	got7fsn_ti	sinapine synthase activity|1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucose:choline 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)transferase activity											RHEA:12024|MetaCyc:2.3.1.91-RXN|KEGG_REACTION:R03075|EC:2.3.1.91		molecular_function											owl:Class	
GO:0140618	biolink:NamedThing	ferric-chelate reductase (NADH) activity	Catalysis of the reaction:  2 Fe3+-siderophore + NAD(+) + H(+) -> 2 Fe2+-siderophore + NADH.	got7fsn_ti	NADH:Fe(3+) oxidoreductase activity|NADH:Fe3+ oxidoreductase activity|iron chelate reductase activity|ferric chelate reductase activity	https://github.com/geneontology/go-ontology/issues/21029					pg	2021-03-09T07:20:30Z				EC:1.16.1.7|MetaCyc:FERRIC-CHELATE-REDUCTASE-RXN|RHEA:15061		molecular_function											owl:Class	
GO:0003692	biolink:NamedThing	left-handed Z-DNA binding	Binding to DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.	got7fsn_ti														molecular_function											owl:Class	
GO:0033462	biolink:NamedThing	GGC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GGC codon.	got7fsn_ti	glycine tRNA				Note that in the standard genetic code, GGC codes for glycine.									molecular_function											owl:Class	
GO:0062052	biolink:NamedThing	starch granule initiation	The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts.	got7fsn_ti							dph	2018-06-08T17:18:57Z						biological_process											owl:Class	
GO:0019252	biolink:NamedThing	starch biosynthetic process	The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants.	got7fsn_ti	starch synthesis|starch anabolism|starch biosynthesis|starch formation											MetaCyc:PWY-622		biological_process											owl:Class	
GO:0071713	biolink:NamedThing	para-aminobenzoyl-glutamate hydrolase activity	Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate.	got7fsn_ti							mah	2010-03-10T01:25:31Z						molecular_function											owl:Class	
GO:0051624	biolink:NamedThing	inhibition of norepinephrine uptake	Any process that prevents the activation of the directed movement of norepinephrine into a cell.	got7fsn_ti	inhibition of norepinephrine import|inhibition of noradrenaline uptake|inhibition of levarterenol uptake													biological_process											owl:Class	
GO:0003850	biolink:NamedThing	2-deoxyglucose-6-phosphatase activity	Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.	got7fsn_ti	2-deoxyglucose-6-phosphate phosphatase activity|2-deoxy-D-glucose-6-phosphate phosphohydrolase activity											KEGG_REACTION:R02587|MetaCyc:3.1.3.68-RXN|EC:3.1.3.68|RHEA:22236		molecular_function											owl:Class	
GO:0018506	biolink:NamedThing	maleylacetate reductase activity	Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.	got7fsn_ti	maleolylacetate reductase activity|3-oxoadipate:NAD(P)+ oxidoreductase activity											UM-BBD_enzymeID:e0063|EC:1.3.1.32|MetaCyc:MALEYLACETATE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0035523	biolink:NamedThing	protein K29-linked deubiquitination	A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.	got7fsn_ti	protein K29-linked deubiquitinylation|protein K29-linked deubiquitylation						bf	2010-05-04T04:33:27Z						biological_process											owl:Class	
GO:0030555	biolink:NamedThing	RNA modification guide activity	Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0099544	biolink:NamedThing	perisynaptic space	The extracellular region immediately adjacent to to a synapse.	got7fsn_ti	extrasynaptic space													cellular_component											owl:Class	
GO:0047732	biolink:NamedThing	CDP-abequose epimerase activity	Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose.	got7fsn_ti	CDP-3,6-dideoxy-D-glucose 2-epimerase activity|cytidine diphosphoabequose epimerase activity|CDP-D-abequose 2-epimerase activity|CDP-paratose epimerase activity|cytidine diphosphodideoxyglucose epimerase activity|cytidine diphosphate paratose-2-epimerase activity|CDP-tyvelose 2-epimerase activity|CDP-paratose 2-epimerase activity|cytidine diphosphoparatose epimerase activity											MetaCyc:RXN-9160|EC:5.1.3.10|RHEA:21656|KEGG_REACTION:R04266		molecular_function											owl:Class	
GO:0102757	biolink:NamedThing	NADPH phosphatase activity	Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate.	got7fsn_ti												MetaCyc:RXN-7703|RHEA:60664		molecular_function											owl:Class	
GO:0050049	biolink:NamedThing	leucine dehydrogenase activity	Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH.	got7fsn_ti	L-leucine:NAD+ oxidoreductase (deaminating)|LeuDH activity|L-leucine dehydrogenase activity|L-leucine:NAD+ oxidoreductase, deaminating											MetaCyc:LEUCINE-DEHYDROGENASE-RXN|EC:1.4.1.9|RHEA:12220		molecular_function											owl:Class	
GO:0047903	biolink:NamedThing	fructose 5-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH.	got7fsn_ti	5-keto-D-fructose reductase (NADP+)|5-ketofructose reductase (NADP+) activity|5-ketofructose reductase (NADP)|5-ketofructose reductase (NADP(+)) activity|D-fructose:NADP+ 5-oxidoreductase activity|D-(-)fructose:(NADP+) 5-oxidoreductase activity|fructose 5-(nicotinamide adenine dinucleotide phosphate) dehydrogenase activity											MetaCyc:FRUCTOSE-5-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.124|RHEA:14069		molecular_function											owl:Class	
GO:0051508	biolink:NamedThing	stigmasterol UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol.	got7fsn_ti												MetaCyc:RXN-12126|RHEA:61828		molecular_function											owl:Class	
GO:0044832	biolink:NamedThing	induction by virus of host cytokine production	The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism.	got7fsn_ti	positive regulation by virus of host cytokine production						jl	2014-02-06T13:04:23Z						biological_process											owl:Class	
GO:0001819	biolink:NamedThing	positive regulation of cytokine production	Any process that activates or increases the frequency, rate or extent of production of a cytokine.	got7fsn_ti	upregulation of cytokine production|stimulation of cytokine production|activation of cytokine production|positive regulation of cytokine secretion|up-regulation of cytokine production|positive regulation of cytokine biosynthetic process|up regulation of cytokine production										GO:0050715|GO:0042108			biological_process											owl:Class	
GO:0044410	biolink:NamedThing	entry into host through natural portals	Penetration by a symbiont into a host organism via naturally occurring openings in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	entry into other organism through natural portals during symbiotic interaction|entry into other organism through natural portals involved in symbiotic interaction										GO:0051829			biological_process											owl:Class	
GO:0061694	biolink:NamedThing	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex	A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity.	got7fsn_ti					An example of this complex is PhnI (P16687) in Escherichia coli.		dph	2015-05-06T10:12:02Z						cellular_component											owl:Class	
GO:0061695	biolink:NamedThing	transferase complex, transferring phosphorus-containing groups	A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).	got7fsn_ti							dph	2015-05-06T11:22:38Z						cellular_component											owl:Class	
GO:0061540	biolink:NamedThing	octopamine secretion, neurotransmission	The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-21T16:24:47Z						biological_process											owl:Class	
GO:0008802	biolink:NamedThing	betaine-aldehyde dehydrogenase activity	Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.	got7fsn_ti	betaine aldehyde oxidase activity|BetB|betaine aldehyde dehydrogenase activity|betaine-aldehyde:NAD+ oxidoreductase activity|BADH activity											EC:1.2.1.8|RHEA:15305|Reactome:R-HSA-6797955|MetaCyc:BADH-RXN		molecular_function											owl:Class	
GO:0000341	biolink:NamedThing	RNA trimethylguanosine cap binding	Binding to the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.	got7fsn_ti	RNA m2,2,7G cap binding													molecular_function											owl:Class	
GO:0061517	biolink:NamedThing	macrophage proliferation	The expansion of a macrophage population by cell division.	got7fsn_ti							dph	2013-04-18T13:17:56Z						biological_process											owl:Class	
GO:0048384	biolink:NamedThing	retinoic acid receptor signaling pathway	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.	got7fsn_ti	retinoic acid receptor signalling pathway|RAR signaling pathway													biological_process											owl:Class	
GO:0006231	biolink:NamedThing	dTMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).	got7fsn_ti	dTMP formation|dTMP anabolism|dTMP biosynthesis|dTMP synthesis													biological_process											owl:Class	
GO:0080002	biolink:NamedThing	UDP-glucose:4-aminobenzoate acylglucosyltransferase activity	Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP.	got7fsn_ti	UDP-glucose:p-aminobenzoate glucosyltransferase activity|UDP-glucose:p-aminobenzoate acylglucosyltransferase activity|UDP-glucose:pABA acylglucosyltransferase activity											MetaCyc:RXN-6142		molecular_function											owl:Class	
GO:1900698	biolink:NamedThing	regulation of o-orsellinic acid biosynthetic process	Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process.	got7fsn_ti	regulation of o-orsellinic acid biosynthesis|regulation of o-orsellinic acid synthesis|regulation of o-orsellinic acid formation|regulation of o-orsellinic acid anabolism						di	2012-05-22T04:56:46Z						biological_process											owl:Class	
GO:0047507	biolink:NamedThing	(deoxy)nucleoside-phosphate kinase activity	Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate.	got7fsn_ti	deoxynucleoside-5'-monophosphate kinase activity|deoxyribonucleoside monophosphokinase activity|ATP:deoxynucleoside-phosphate phosphotransferase activity|deoxynucleoside monophosphate kinase activity											MetaCyc:DEOXYNUCLEOSIDE-PHOSPHATE-KINASE-RXN|RHEA:11216|EC:2.7.4.13		molecular_function											owl:Class	
GO:0048577	biolink:NamedThing	negative regulation of short-day photoperiodism, flowering	Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	got7fsn_ti	downregulation of short-day photoperiodism, flowering|down regulation of short-day photoperiodism, flowering|down-regulation of short-day photoperiodism, flowering|inhibition of short-day photoperiodism, flowering													biological_process											owl:Class	
GO:0033870	biolink:NamedThing	thiol sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate.	got7fsn_ti	adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase activity|PAPS sulfotransferase activity|3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase activity											EC:2.8.2.16|MetaCyc:THIOL-SULFOTRANSFERASE-RXN|RHEA:14637		molecular_function											owl:Class	
GO:0019231	biolink:NamedThing	perception of static position	The perception of the orientation of different parts of the body with respect to one another.	got7fsn_ti														biological_process											owl:Class	
GO:0061665	biolink:NamedThing	SUMO ligase activity	Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3						dph	2014-11-06T14:00:44Z						molecular_function											owl:Class	
GO:0120066	biolink:NamedThing	pyloric canal smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.	got7fsn_ti							krc	2017-06-13T22:37:51Z						biological_process											owl:Class	
GO:0120064	biolink:NamedThing	stomach pylorus smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.	got7fsn_ti							krc	2017-06-13T22:32:04Z						biological_process											owl:Class	
GO:0046174	biolink:NamedThing	polyol catabolic process	The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.	got7fsn_ti	polyol degradation|polyol catabolism|polyol breakdown|polyhydric alcohol catabolic process													biological_process											owl:Class	
GO:0015987	biolink:NamedThing	GTP synthesis coupled proton transport	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0042279	biolink:NamedThing	nitrite reductase (cytochrome, ammonia-forming) activity	Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+.	got7fsn_ti	cytochrome c552 activity|ammonia:ferricytochrome-c oxidoreductase activity|cytochrome c nitrite reductase activity|multiheme nitrite reductase activity|nitrite reductase (cytochrome; ammonia-forming)											RHEA:13089|Wikipedia:Cytochrome_c_nitrite_reductase|EC:1.7.2.2|MetaCyc:1.7.2.2-RXN		molecular_function											owl:Class	
GO:0051639	biolink:NamedThing	actin filament network formation	The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.	got7fsn_ti	actin gel biosynthesis|actin gel formation													biological_process											owl:Class	
GO:0034606	biolink:NamedThing	response to hermaphrodite contact	The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.	got7fsn_ti														biological_process											owl:Class	
GO:0010306	biolink:NamedThing	rhamnogalacturonan II biosynthetic process	The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms.	got7fsn_ti														biological_process											owl:Class	
GO:0089714	biolink:NamedThing	UDP-N-acetyl-D-mannosamine dehydrogenase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+.	got7fsn_ti												EC:1.1.1.336|RHEA:25780		molecular_function											owl:Class	
GO:0070573	biolink:NamedThing	metallodipeptidase activity	Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	got7fsn_ti	metalloexodipeptidase activity|metallo-exo-dipeptidase activity						mah	2009-04-15T03:11:29Z				Reactome:R-HSA-2065355|Reactome:R-HSA-2022398|Reactome:R-HSA-2022405		molecular_function											owl:Class	
GO:0016805	biolink:NamedThing	dipeptidase activity	Catalysis of the hydrolysis of a dipeptide.	got7fsn_ti	cytosolic dipeptidase activity										GO:0102008	Reactome:R-HSA-266012|MetaCyc:3.4.13.18-RXN|EC:3.4.13.21|Reactome:R-HSA-9026771|EC:3.4.13.-|Reactome:R-HSA-5693783|Reactome:R-HSA-5433067|MetaCyc:3.4.13.21-RXN|EC:3.4.13.18		molecular_function											owl:Class	
GO:0047783	biolink:NamedThing	corticosterone 18-monooxygenase activity	Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O.	got7fsn_ti	corticosterone 18-hydroxylase activity|corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)|corticosterone methyl oxidase activity											MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN|RHEA:11872|EC:1.14.15.5		molecular_function											owl:Class	
GO:0035038	biolink:NamedThing	female pronucleus assembly	Assembly of the haploid nucleus of the unfertilized egg.	got7fsn_ti	female pronucleus assembly													biological_process											owl:Class	
GO:0018565	biolink:NamedThing	dihydroxydibenzothiophene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0162		molecular_function											owl:Class	
GO:0031749	biolink:NamedThing	D2 dopamine receptor binding	Binding to a D2 dopamine receptor.	got7fsn_ti	D2 dopamine receptor ligand													molecular_function											owl:Class	
GO:0043262	biolink:NamedThing	adenosine-diphosphatase activity	Catalysis of the reaction: ADP + H2O = AMP + phosphate.	got7fsn_ti	ATP-diphosphatase activity|ADPase|adenosine diphosphatase activity|ATP diphosphohydrolase activity|ADPase activity											RHEA:61436|MetaCyc:APYRASE-RXN		molecular_function											owl:Class	
GO:0097611	biolink:NamedThing	dinoflagellate cingulum	A cell surface furrow that wraps around a dinoflagellate cell; the transverse flagellum lies in it.	got7fsn_ti	cingulum|transverse groove|girdle				The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-06-09T11:28:22Z						cellular_component											owl:Class	
GO:0034987	biolink:NamedThing	immunoglobulin receptor binding	Binding to one or more specific sites on an immunoglobulin receptor molecule.	got7fsn_ti	Fc receptor binding													molecular_function											owl:Class	
GO:0072599	biolink:NamedThing	establishment of protein localization to endoplasmic reticulum	The directed movement of a protein to a specific location in the endoplasmic reticulum.	got7fsn_ti	establishment of protein localisation to endoplasmic reticulum|establishment of protein localization to ER|establishment of protein localization in endoplasmic reticulum|establishment of protein localisation to ER						mah	2011-02-14T02:23:41Z						biological_process											owl:Class	
GO:0003871	biolink:NamedThing	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate.	got7fsn_ti	5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity|methionine synthase (cobalamin-independent) activity|MetE|cobalamin-independent methionine synthase activity|tetrahydropteroylglutamate-homocysteine transmethylase activity|methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase activity|homocysteine methylase activity|methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase activity|tetrahydropteroyltriglutamate methyltransferase activity											MetaCyc:HOMOCYSMET-RXN|RHEA:21196|KEGG_REACTION:R04405|EC:2.1.1.14		molecular_function											owl:Class	
GO:0051996	biolink:NamedThing	squalene synthase activity	Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate.	got7fsn_ti	squalene synthetase activity				Note that the two reactions performed by EC:2.5.1.21 are represented in GO by 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310' and 'squalene synthase activity ; GO:0051996'.		ai	2010-07-16T05:10:24Z				MetaCyc:RXN66-281|EC:2.5.1.21		molecular_function											owl:Class	
GO:0047720	biolink:NamedThing	indoleacetaldoxime dehydratase activity	Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H(2)O.	got7fsn_ti	(indol-3-yl)acetaldehyde-oxime hydro-lyase activity|indoleacetaldoxime hydro-lyase activity|3-indoleacetaldoxime hydro-lyase activity|(indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming]|indole-3-acetaldoxime hydro-lyase activity|indole-3-acetaldehyde-oxime hydro-lyase activity											RHEA:23156|KEGG_REACTION:R04093|MetaCyc:RXN-1403|EC:4.99.1.6		molecular_function											owl:Class	
GO:0060925	biolink:NamedThing	ventricular cardiac muscle cell fate commitment	The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	got7fsn_ti	ventricular cardiomyocyte cell fate commitment|ventricular heart muscle cell fate commitment						dph	2009-09-29T11:49:39Z						biological_process											owl:Class	
GO:0018145	biolink:NamedThing	protein-DNA covalent cross-linking via peptidyl-serine	The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine.	got7fsn_ti	DNA-protein covalent cross-linking via peptidyl-serine											RESID:AA0246		biological_process											owl:Class	
GO:0038127	biolink:NamedThing	ERBB signaling pathway	A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	ErbB signaling|EGFR family signaling pathway|ERBB signalling pathway|EGF receptor family signaling pathway						bf	2012-03-30T09:23:01Z						biological_process											owl:Class	
GO:0061577	biolink:NamedThing	calcium ion transmembrane transport via high voltage-gated calcium channel	A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.	got7fsn_ti	generation of L-type calcium current						dph	2013-11-15T16:20:27Z						biological_process											owl:Class	
GO:0034242	biolink:NamedThing	negative regulation of syncytium formation by plasma membrane fusion	Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0008118	biolink:NamedThing	N-acetyllactosaminide alpha-2,3-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein.	got7fsn_ti	alpha2->3 sialyltransferase activity|cytidine monophosphoacetylneuraminate-beta-galactosyl(1->4)acetylglucosaminide alpha2->3-sialyltransferase activity|SiaT|CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase activity											EC:2.4.99.6|RHEA:52316|MetaCyc:2.4.99.6-RXN		molecular_function											owl:Class	
GO:0008213	biolink:NamedThing	protein alkylation	The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.	got7fsn_ti	protein amino acid alkylation													biological_process											owl:Class	
GO:0090685	biolink:NamedThing	RNA localization to nucleus	A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.	got7fsn_ti	RNA localisation to nucleus						tb	2016-07-19T17:00:49Z						biological_process											owl:Class	
GO:0035669	biolink:NamedThing	TRAM-dependent toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	got7fsn_ti	TRAM-dependent toll-like receptor 4 signalling pathway|TRAM-dependent TLR4 signaling pathway						bf	2011-02-01T02:41:09Z						biological_process											owl:Class	
GO:0097498	biolink:NamedThing	endothelial tube lumen extension	Any endothelial tube morphogenesis process by which the tube is increased in length.	got7fsn_ti							pr	2013-08-12T13:49:54Z						biological_process											owl:Class	
GO:0004492	biolink:NamedThing	methylmalonyl-CoA decarboxylase activity	Catalysis of the reaction: (S)-2-methyl-3-oxopropanoyl-CoA = propanoyl-CoA + CO2.	got7fsn_ti	methylmalonyl-coenzyme A decarboxylase activity|(S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming)|(S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase activity|(S)-methylmalonyl-CoA carboxy-lyase activity											EC:7.2.4.3|RHEA:21396|MetaCyc:METHYLMALONYL-COA-DECARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0016618	biolink:NamedThing	hydroxypyruvate reductase activity	Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.	got7fsn_ti	D-glycerate dehydrogenase activity|beta-hydroxypyruvate reductase activity|D-glycerate:NADP+ 2-oxidoreductase activity|NADH:hydroxypyruvate reductase activity											MetaCyc:RXN0-300|RHEA:18657|MetaCyc:HYDROXYPYRUVATE-REDUCTASE-RXN|EC:1.1.1.81		molecular_function											owl:Class	
GO:0047962	biolink:NamedThing	glycine N-benzoyltransferase activity	Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+).	got7fsn_ti	benzoyl-CoA:glycine N-acyltransferase activity|benzoyl CoA-amino acid N-acyltransferase activity|benzoyl-CoA:glycine N-benzoyltransferase activity											KEGG_REACTION:R02452|RHEA:18493|Reactome:R-HSA-159574|MetaCyc:GLYCINE-N-BENZOYLTRANSFERASE-RXN|EC:2.3.1.71|Reactome:R-HSA-159566		molecular_function											owl:Class	
GO:0019160	biolink:NamedThing	NMN nucleosidase activity	Catalysis of the reaction: H(2)O + nicotinamide mononucleotide = D-ribose 5-phosphate + H(+) + nicotinamide.	got7fsn_ti	nicotinamide-nucleotide phosphoribohydrolase activity|NMN glycohydrolase activity|nicotinamide mononucleotide nucleosidase activity|NMNase activity|nicotinamide mononucleotidase activity|NMNGhase activity											MetaCyc:NMNNUCLEOSID-RXN|EC:3.2.2.14|RHEA:23140|KEGG_REACTION:R01270		molecular_function											owl:Class	
GO:0061266	biolink:NamedThing	mesonephric interstitial fibroblast differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state.	got7fsn_ti	mesonephros interstitial cell differentiation						dph	2010-08-30T03:12:17Z						biological_process											owl:Class	
GO:0097347	biolink:NamedThing	TAM protein secretion complex	A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane.	got7fsn_ti	translocation and assembly module protein complex						pr	2012-06-21T10:44:15Z						cellular_component											owl:Class	
GO:0052700	biolink:NamedThing	ergothioneine catabolic process	The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.	got7fsn_ti	ergothioneine breakdown|2-mercaptoergothioneine trimethylbetaine breakdown|2-mercaptoergothioneine trimethylbetaine catabolic process|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate catabolic process|2-mercaptoergothioneine trimethylbetaine catabolism|ergothioneine catabolism|ergothioneine degradation|2-mercaptoergothioneine trimethylbetaine degradation						ai	2011-08-01T03:56:22Z						biological_process											owl:Class	
GO:0071098	biolink:NamedThing	alpha6-beta4 integrin-Fyn complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.	got7fsn_ti	ITGA6-ITGB4-FYN complex						mah	2009-11-06T04:52:10Z						cellular_component											owl:Class	
GO:0009859	biolink:NamedThing	pollen hydration	The process in which water is taken up by pollen.	got7fsn_ti														biological_process											owl:Class	
GO:0042978	biolink:NamedThing	ornithine decarboxylase activator activity	Binds to and increases ornithine decarboxylase activity.	got7fsn_ti	L-ornithine carboxy-lyase activator activity													molecular_function											owl:Class	
GO:0042979	biolink:NamedThing	ornithine decarboxylase regulator activity	Binds to and modulates the activity of the enzyme ornithine decarboxylase.	got7fsn_ti														molecular_function											owl:Class	
GO:0051016	biolink:NamedThing	barbed-end actin filament capping	The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.	got7fsn_ti	plus-end actin filament capping activity|barbed-end actin capping activity|plus-end F-actin capping activity|barbed-end F-actin capping activity													biological_process											owl:Class	
GO:0051693	biolink:NamedThing	actin filament capping	The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.	got7fsn_ti	actin capping activity|F-actin capping activity													biological_process											owl:Class	
GO:0006788	biolink:NamedThing	heme oxidation	The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.	got7fsn_ti	haem oxidation													biological_process											owl:Class	
GO:0042168	biolink:NamedThing	heme metabolic process	The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.	got7fsn_ti	haem metabolism|haem metabolic process|heme metabolism													biological_process											owl:Class	
GO:0033414	biolink:NamedThing	UGC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UGC codon.	got7fsn_ti	TGC codon-amino acid adaptor activity|cysteine tRNA				Note that in the standard genetic code, TGC codes for cysteine.									molecular_function											owl:Class	
GO:0045726	biolink:NamedThing	positive regulation of integrin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.	got7fsn_ti	positive regulation of integrin formation|positive regulation of integrin biosynthesis|activation of integrin biosynthetic process|positive regulation of integrin synthesis|upregulation of integrin biosynthetic process|stimulation of integrin biosynthetic process|positive regulation of integrin anabolism|up-regulation of integrin biosynthetic process|up regulation of integrin biosynthetic process													biological_process											owl:Class	
GO:0019357	biolink:NamedThing	nicotinate nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid).	got7fsn_ti	nicotinate nucleotide synthesis|nicotinate nucleotide formation|nicotinate nucleotide anabolism|nicotinate nucleotide biosynthesis													biological_process											owl:Class	
GO:0046980	biolink:NamedThing	tapasin binding	Binding to tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules.	got7fsn_ti	TAPBP binding|TAP binding protein binding													molecular_function											owl:Class	
GO:0043890	biolink:NamedThing	N-acetylgalactosamine-6-sulfatase activity	Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.	got7fsn_ti	chondroitinase|acetylgalactosamine 6-sulfatase activity|galactose-6-sulfate sulfatase activity|N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity|N-acetylgalactosamine 6-sulfatase activity|chondroitin sulfatase|chondroitinsulfatase|N-acetylgalactosamine-6-sulfate sulfatase activity											Reactome:R-HSA-1630304|Reactome:R-HSA-2263490|MetaCyc:3.1.6.4-RXN|EC:3.1.6.4		molecular_function											owl:Class	
GO:1990867	biolink:NamedThing	response to gastrin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.	got7fsn_ti							sl	2015-09-25T16:22:39Z						biological_process											owl:Class	
GO:1900793	biolink:NamedThing	shamixanthone biosynthetic process	The chemical reactions and pathways resulting in the formation of shamixanthone.	got7fsn_ti	shamixanthone synthesis|shamixanthone biosynthesis|shamixanthone formation|shamixanthone anabolism						di	2012-06-04T09:40:49Z						biological_process											owl:Class	
GO:0010243	biolink:NamedThing	response to organonitrogen compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.	got7fsn_ti	response to organic nitrogen													biological_process											owl:Class	
GO:0003865	biolink:NamedThing	3-oxo-5-alpha-steroid 4-dehydrogenase activity	Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor.	got7fsn_ti	3-oxosteroid delta4-dehydrogenase|3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity|testosterone 5alpha-reductase|steroid delta4-5alpha-reductase activity|delta4-3-keto steroid 5alpha-reductase activity|steroid 5-alpha-reductase activity|steroid 5alpha-reductase|delta4-3-oxo steroid reductase activity|3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity|5alpha-reductase|delta4-5alpha-dehydrogenase activity|3-keto-delta4-steroid-5alpha-reductase activity|delta4-3-ketosteroid5alpha-oxidoreductase activity|steroid 5 alpha reductase|delta4-3-oxosteroid-5alpha-reductase|4-ene-3-ketosteroid-5alpha-oxidoreductase activity|3-oxo-5alpha-steroid delta4-dehydrogenase activity|3-oxo-5alpha-steroid 4-dehydrogenase activity											MetaCyc:1.3.99.5-RXN|Reactome:R-HSA-9705714|Reactome:R-HSA-9705713|EC:1.3.99.5|Reactome:R-HSA-469659		molecular_function											owl:Class	
GO:0003774	biolink:NamedThing	cytoskeletal motor activity	Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).	got7fsn_ti	motor activity	https://github.com/geneontology/go-ontology/issues/21756|https://github.com/geneontology/go-ontology/issues/19590										Reactome:R-HSA-1861595		molecular_function											owl:Class	
GO:0071121	biolink:NamedThing	alpha9-beta1 integrin-VEGF-D complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.	got7fsn_ti	ITGA9-ITGB1-FIGF complex						mah	2009-11-13T02:21:37Z						cellular_component											owl:Class	
GO:0050038	biolink:NamedThing	L-xylulose reductase (NADP+) activity	Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH.	got7fsn_ti	L-xylulose reductase activity											EC:1.1.1.10|KEGG_REACTION:R01904|RHEA:17025|MetaCyc:L-XYLULOSE-REDUCTASE-RXN|Reactome:R-HSA-5662851|Reactome:R-HSA-5661240		molecular_function											owl:Class	
GO:0061985	biolink:NamedThing	carbon catabolite repression	A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources.	got7fsn_ti							dph	2018-02-15T16:49:48Z						biological_process											owl:Class	
GO:0070818	biolink:NamedThing	protoporphyrinogen oxidase activity	Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.	got7fsn_ti	protoporphyrinogen-IX oxidase activity|protoporphyrinogen IX oxidase activity|protoporphyrinogenase activity						mah	2009-07-20T02:41:12Z						molecular_function											owl:Class	
GO:1990620	biolink:NamedThing	ANPR-A receptor complex	A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A receptor complex, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure.	got7fsn_ti	NPR1 receptor complex				An example of this is Npr1 in rat (UniProt symbol P18910) in PMID:15117952 (inferred from direct assay).		ame	2015-01-28T16:03:22Z						cellular_component											owl:Class	
GO:0007561	biolink:NamedThing	imaginal disc eversion	The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis.	got7fsn_ti														biological_process											owl:Class	
GO:0031477	biolink:NamedThing	myosin VII complex	A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.	got7fsn_ti														cellular_component											owl:Class	
GO:0033906	biolink:NamedThing	hyaluronoglucuronidase activity	Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.	got7fsn_ti	hyaluronate 3-glycanohydrolase activity|orgelase activity|glucuronoglucosaminoglycan hyaluronate lyase activity|hyaluronidase activity											EC:3.2.1.36|MetaCyc:3.2.1.36-RXN		molecular_function											owl:Class	
GO:0021701	biolink:NamedThing	cerebellar Golgi cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0043468	biolink:NamedThing	regulation of fucose catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose.	got7fsn_ti														biological_process											owl:Class	
GO:1990460	biolink:NamedThing	leptin receptor binding	Binding to a leptin receptor.	got7fsn_ti							tb	2014-08-18T20:17:43Z						molecular_function											owl:Class	
GO:0003054	biolink:NamedThing	circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus	The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours.	got7fsn_ti	master pacemaker clock regulation of blood pressure|SCN regulation of blood pressure													biological_process											owl:Class	
GO:0000002	biolink:NamedThing	mitochondrial genome maintenance	The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.	got7fsn_ti														biological_process											owl:Class	
GO:0070005	biolink:NamedThing	cysteine-type aminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681										EC:3.4.18.-		molecular_function											owl:Class	
GO:0008062	biolink:NamedThing	eclosion rhythm	The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.	got7fsn_ti														biological_process											owl:Class	
GO:0031534	biolink:NamedThing	minus-end directed microtubule sliding	The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.	got7fsn_ti														biological_process											owl:Class	
GO:0032978	biolink:NamedThing	protein insertion into membrane from inner side	The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side.	got7fsn_ti	insertion of proteins into membrane from the inner side													biological_process											owl:Class	
GO:0019615	biolink:NamedThing	catechol catabolic process, ortho-cleavage	The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups.	got7fsn_ti	catechol degradation, ortho-cleavage|catechol breakdown, ortho-cleavage											MetaCyc:CATECHOL-ORTHO-CLEAVAGE-PWY		biological_process											owl:Class	
GO:0002263	biolink:NamedThing	cell activation involved in immune response	A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	cell activation during immune response													biological_process											owl:Class	
GO:0008819	biolink:NamedThing	cobinamide kinase activity	Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0031610	biolink:NamedThing	nuclear proteasome regulatory particle, base subcomplex	The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:1900570	biolink:NamedThing	diorcinol metabolic process	The chemical reactions and pathways involving diorcinol.	got7fsn_ti	diorcinol metabolism						di	2012-05-15T06:35:01Z						biological_process											owl:Class	
GO:0018782	biolink:NamedThing	cis-chloroacrylic acid dehalogenase activity	Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde.	got7fsn_ti												UM-BBD_reactionID:r0688		molecular_function											owl:Class	
GO:0047923	biolink:NamedThing	gentisate decarboxylase activity	Catalysis of the reaction: 2,5-dihydroxybenzoate + H(+) = CO(2) + hydroquinone.	got7fsn_ti	2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming)|gentisate carboxy-lyase activity|2,5-dihydroxybenzoate decarboxylase activity											KEGG_REACTION:R02489|RHEA:21312|MetaCyc:GENTISATE-DECARBOXYLASE-RXN|EC:4.1.1.62		molecular_function											owl:Class	
GO:1990131	biolink:NamedThing	Gtr1-Gtr2 GTPase complex	A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins.	got7fsn_ti							rb	2013-06-25T20:39:16Z						cellular_component											owl:Class	
GO:0030789	biolink:NamedThing	precorrin-3B C17-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4.	got7fsn_ti	precorrin-3 methyltransferase activity|CobJ|precorrin-3 methylase activity|S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase activity											MetaCyc:2.1.1.131-RXN|EC:2.1.1.131|RHEA:12761		molecular_function											owl:Class	
GO:0044078	biolink:NamedThing	positive regulation by symbiont of host receptor-mediated endocytosis	Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.	got7fsn_ti	positive regulation of host receptor-mediated endocytosis by symbiont													biological_process											owl:Class	
GO:0048260	biolink:NamedThing	positive regulation of receptor-mediated endocytosis	Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.	got7fsn_ti	activation of receptor mediated endocytosis|stimulation of receptor mediated endocytosis|up regulation of receptor mediated endocytosis|positive regulation of receptor mediated endocytosis|upregulation of receptor mediated endocytosis|up-regulation of receptor mediated endocytosis													biological_process											owl:Class	
GO:0120211	biolink:NamedThing	proacrosomal vesicle fusion	Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.	got7fsn_ti							krc	2019-05-22T17:12:55Z						biological_process											owl:Class	
GO:0050538	biolink:NamedThing	N-carbamoyl-L-amino-acid hydrolase activity	Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate.	got7fsn_ti	L-carbamoylase activity|N-carbamoyl-L-amino acid amidohydrolase activity											EC:3.5.1.87|RHEA:17581|MetaCyc:3.5.1.87-RXN		molecular_function											owl:Class	
GO:0036250	biolink:NamedThing	peroxisome transport along microtubule	The directed movement of a peroxisome along a microtubule, mediated by motor proteins.	got7fsn_ti							bf	2012-05-31T03:09:09Z						biological_process											owl:Class	
GO:0019492	biolink:NamedThing	proline salvage	Any process which produces the amino acid proline from derivatives of it, without de novo synthesis.	got7fsn_ti	proline cycling													biological_process											owl:Class	
GO:0043723	biolink:NamedThing	2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity	Catalysis of the reaction: 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonia.	got7fsn_ti	DRAP deaminase activity|2,5-diamino-6-(5-phosphoribitylamino)pyrimidin-4(3H)-one deaminase activity										GO:0017173	MetaCyc:RXN-10058		molecular_function											owl:Class	
GO:0047823	biolink:NamedThing	D-glutamyltransferase activity	Catalysis of the reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-peptide.	got7fsn_ti	D-glutamyl transpeptidase activity|D-gamma-glutamyl transpeptidase activity|glutamine:D-glutamyl-peptide 5-glutamyltransferase activity											RHEA:35623|EC:2.3.2.1|MetaCyc:D-GLUTAMYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0032629	biolink:NamedThing	interleukin-25 production	The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-25 anabolism|interleukin-25 biosynthesis|IL-25 production|IL-25 secretion|interleukin-25 formation|interleukin-25 synthesis|interleukin-25 biosynthetic process|IL17E secretion|interleukin-25 secretion										GO:0045525|GO:0072623			biological_process											owl:Class	
GO:0047002	biolink:NamedThing	L-arabinitol 2-dehydrogenase activity	Catalysis of the reaction: L-arabinitol + NAD(+) = L-ribulose + H(+) + NADH.	got7fsn_ti	L-arabinitol 2-dehydrogenase (ribulose forming) activity											EC:1.1.1.13|RHEA:21356|MetaCyc:1.1.1.13-RXN|KEGG_REACTION:R02441		molecular_function											owl:Class	
GO:0046729	biolink:NamedThing	viral procapsid	A stable empty viral capsid produced during the assembly of viruses.	got7fsn_ti														cellular_component											owl:Class	
GO:0071794	biolink:NamedThing	CAP-Gly domain binding	Binding to a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets.	got7fsn_ti							mah	2010-09-02T02:02:53Z						molecular_function											owl:Class	
GO:0060957	biolink:NamedThing	endocardial cell fate commitment	The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.	got7fsn_ti							dph	2009-09-29T03:24:29Z						biological_process											owl:Class	
GO:1902584	biolink:NamedThing	positive regulation of response to water deprivation	Any process that activates or increases the frequency, rate or extent of response to water deprivation.	got7fsn_ti	activation of response to thirst|up-regulation of response to drought|activation of drought tolerance|up regulation of drought tolerance|activation of response to water deprivation|positive regulation of response to drought|up-regulation of response to dehydration|activation of response to dehydration|upregulation of response to drought|up-regulation of drought tolerance|up-regulation of response to thirst|up-regulation of response to water deprivation|upregulation of drought tolerance|positive regulation of response to dehydration|up regulation of response to thirst|positive regulation of response to thirst|upregulation of response to water deprivation|upregulation of response to thirst|up regulation of response to drought|activation of response to drought|positive regulation of drought tolerance|up regulation of response to dehydration|upregulation of response to dehydration|up regulation of response to water deprivation						tb	2013-12-19T00:31:58Z						biological_process											owl:Class	
GO:2000070	biolink:NamedThing	regulation of response to water deprivation	Any process that modulates the frequency, rate or extent of response to water deprivation.	got7fsn_ti	regulation of drought tolerance|regulation of response to drought|regulation of response to thirst|regulation of response to dehydration						tb	2010-08-23T11:32:32Z						biological_process											owl:Class	
GO:0047013	biolink:NamedThing	cholate 12-alpha dehydrogenase activity	Catalysis of the reaction: cholate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH.	got7fsn_ti	12alpha-hydroxysteroid dehydrogenase activity|12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity|NADP-12alpha-hydroxysteroid dehydrogenase activity|NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity|12-alpha-hydroxysteroid dehydrogenase activity|12alpha-hydroxy steroid dehydrogenase activity											MetaCyc:1.1.1.176-RXN|KEGG_REACTION:R02793|EC:1.1.1.176|RHEA:14129		molecular_function											owl:Class	
GO:0061473	biolink:NamedThing	murein tripeptide carboxypeptidase activity	Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate.	got7fsn_ti							dph	2012-11-06T12:23:39Z						molecular_function											owl:Class	
GO:2001004	biolink:NamedThing	negative regulation of pectin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process.	got7fsn_ti	negative regulation of pectin degradation|negative regulation of pectin catabolism|negative regulation of pectin breakdown						tt	2011-08-08T03:24:06Z						biological_process											owl:Class	
GO:0021621	biolink:NamedThing	hypoglossal nerve structural organization	The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	got7fsn_ti	CN XII structural organization|hypoglossal nerve structural organisation													biological_process											owl:Class	
GO:0019304	biolink:NamedThing	anaerobic rhamnose catabolic process	The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen.	got7fsn_ti	anaerobic rhamnose breakdown|anaerobic rhamnose degradation|anaerobic rhamnose catabolism													biological_process											owl:Class	
GO:0019301	biolink:NamedThing	rhamnose catabolic process	The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.	got7fsn_ti	rhamnose degradation|rhamnose catabolism|rhamnose breakdown											MetaCyc:RHAMCAT-PWY		biological_process											owl:Class	
GO:0047792	biolink:NamedThing	cyanohydrin beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside.	got7fsn_ti	uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase activity|UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity|UDP-D-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity|uridine diphosphoglucose-cyanohydrin glucosyltransferase activity|UGT85B1 activity|UDP-glucose-p-hydroxymandelonitrile glucosyltransferase activity|cyanohydrin b-glucosyltransferase activity|UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase activity|uridine diphosphoglucose:aldehyde cyanohydrin beta-glucosyltransferase activity											EC:2.4.1.85|RHEA:12853		molecular_function											owl:Class	
GO:0035914	biolink:NamedThing	skeletal muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.	got7fsn_ti							bf	2011-06-24T02:36:19Z						biological_process											owl:Class	
PATO:0000001	biolink:NamedThing			got7fsn_ti																									owl:Class	
BFO:0000020	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031169	biolink:NamedThing	ferrichrome biosynthetic process	The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.	got7fsn_ti	ferrichrome anabolism|ferrichrome synthesis|ferrichrome biosynthetic process, peptide modification|ferrichrome formation|ferrichrome biosynthetic process, peptide formation|ferrichrome biosynthesis										GO:0031199|GO:0031200			biological_process											owl:Class	
GO:0019539	biolink:NamedThing	hydroxymate-containing siderophore biosynthetic process	The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20975									GO:0031198|GO:0031197			biological_process											owl:Class	
GO:0097309	biolink:NamedThing	cap1 mRNA methylation	Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.	got7fsn_ti	cap1 mRNA capping						pr	2012-05-23T04:03:13Z						biological_process											owl:Class	
GO:0050092	biolink:NamedThing	meso-tartrate dehydrogenase activity	Catalysis of the reaction: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH.	got7fsn_ti	meso-tartrate:NAD+ oxidoreductase activity											MetaCyc:MESO-TARTRATE-DEHYDROGENASE-RXN|KEGG_REACTION:R02544|EC:1.3.1.7|RHEA:18553		molecular_function											owl:Class	
GO:0031601	biolink:NamedThing	nuclear proteasome core complex	The core complex of a proteasome located in the nucleus of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0102676	biolink:NamedThing	avenasterol-desaturase activity	Catalysis of the reaction: avenasterol + O2 + NADPH + H+ <=> 5-dehydroavenasterol + 2 H2O + NADP.	got7fsn_ti												MetaCyc:RXN-4209		molecular_function											owl:Class	
GO:0102722	biolink:NamedThing	gamma-hydroxybutyrate dehydrogenase activity (NAD(P)-dependent	Catalysis of the reaction: 4-hydroxybutyrate + NAD(P) = 4-oxobutanoate + H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-6903		molecular_function											owl:Class	
GO:0034057	biolink:NamedThing	RNA strand-exchange activity	Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.	got7fsn_ti														molecular_function											owl:Class	
GO:0090601	biolink:NamedThing	enucleation	The process in which nucleated precursor cells lose their nucleus.	got7fsn_ti							tb	2014-09-05T16:25:16Z						biological_process											owl:Class	
GO:0061628	biolink:NamedThing	H3K27me3 modified histone binding	Binding to a histone H3 in which the lysine residue at position 27 has been modified by trimethylation.	got7fsn_ti	H3-K27me3 modified histone binding						dph	2014-05-14T15:36:53Z						molecular_function											owl:Class	
GO:0045722	biolink:NamedThing	positive regulation of gluconeogenesis	Any process that activates or increases the frequency, rate or extent of gluconeogenesis.	got7fsn_ti	upregulation of gluconeogenesis|stimulation of gluconeogenesis|activation of gluconeogenesis|up regulation of gluconeogenesis|up-regulation of gluconeogenesis													biological_process											owl:Class	
GO:0019170	biolink:NamedThing	methylglyoxal reductase (NADH-dependent) activity	Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+.	got7fsn_ti	methylglyoxal reductase activity|D-lactaldehyde dehydrogenase activity|(R)-lactaldehyde:NAD+ oxidoreductase activity											EC:1.1.1.78|MetaCyc:D-LACTALDEHYDE-DEHYDROGENASE-RXN|RHEA:24528		molecular_function											owl:Class	
GO:0047373	biolink:NamedThing	acetoxybutynylbithiophene deacetylase activity	Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+).	got7fsn_ti	5-(4-acetoxy-1-butynyl)-2,2'-bithiophene:acetate esterase activity|5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene O-acetylhydrolase activity|acetoxybutynylbithiophene esterase activity											RHEA:11548|EC:3.1.1.54|KEGG_REACTION:R04490|MetaCyc:3.1.1.54-RXN		molecular_function											owl:Class	
GO:0010422	biolink:NamedThing	regulation of brassinosteroid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.	got7fsn_ti														biological_process											owl:Class	
GO:0039720	biolink:NamedThing	virogenic stroma	A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled.	got7fsn_ti	VS						bf	2013-12-19T15:45:32Z						cellular_component											owl:Class	
GO:0103080	biolink:NamedThing	methylthiopropylmalate isomerase activity	Catalysis of the reaction: 2-(3-methylthiopropyl)malate(2-) <=> 3-(3'-methylthio)propylmalate.	got7fsn_ti												RHEA:50644|MetaCyc:RXNQT-4164		molecular_function											owl:Class	
GO:0009035	biolink:NamedThing	type I site-specific deoxyribonuclease activity	Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.	got7fsn_ti	ATP-dependent DNase activity|deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)|deoxyribonuclease (adenosine triphosphate-hydrolyzing)|adenosine triphosphate-dependent deoxyribonuclease activity|type I restriction enzyme activity|type I site-specific deoxyribonuclease activity	https://github.com/geneontology/go-ontology/issues/21612										EC:3.1.21.3|MetaCyc:3.1.21.3-RXN		molecular_function											owl:Class	
GO:1904090	biolink:NamedThing	peptidase inhibitor complex	A protein complex which is capable of peptidase inhibitor activity.	got7fsn_ti	Cathepsin-B - cystatin-A complex				An example of this is Cystatin-A in human (UniProt symbol P01040) in PMID:20860624 (inferred from physical interaction).		bhm	2015-03-26T10:16:27Z						cellular_component											owl:Class	
GO:0018110	biolink:NamedThing	histone arginine kinase activity	Catalysis of the reaction: histone L-arginine + ATP = histone N(omega)-phospho-L-arginine + ADP + 2 H(+).	got7fsn_ti	histone-arginine kinase activity											EC:2.7.3.-		molecular_function											owl:Class	
GO:0102856	biolink:NamedThing	1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity	Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8323|EC:1.14.19.25		molecular_function											owl:Class	
GO:0030417	biolink:NamedThing	nicotianamine metabolic process	The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.	got7fsn_ti	nicotianamine metabolism													biological_process											owl:Class	
GO:0043759	biolink:NamedThing	methylbutanoate-CoA ligase activity	Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = AMP +  diphosphate + 2-methylbutanoyl-CoA.	got7fsn_ti	branched chain acyl-CoA synthetase (ADP-forming) activity|branched chain acyl CoA synthetase (ADP-forming) activity|branched-chain acyl-CoA synthetase (ADP-forming) activity|branched-chain acyl CoA synthetase (ADP-forming) activity	https://github.com/geneontology/go-ontology/issues/18967										RHEA:46180		molecular_function											owl:Class	
GO:1900810	biolink:NamedThing	helvolic acid metabolic process	The chemical reactions and pathways involving helvolic acid.	got7fsn_ti	Fumigacin metabolic process|Fumigacin metabolism|helvolic acid metabolism						di	2012-06-04T10:02:28Z						biological_process											owl:Class	
GO:0008396	biolink:NamedThing	oxysterol 7-alpha-hydroxylase activity	Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O.	got7fsn_ti	cytochrome P450 CYP7B1											Reactome:R-HSA-191972|Reactome:R-HSA-192178|Reactome:R-HSA-192065|Reactome:R-HSA-5602885		molecular_function											owl:Class	
GO:0033839	biolink:NamedThing	flavonol-3-O-glycoside glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.	got7fsn_ti	UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase activity											RHEA:23544|MetaCyc:2.4.1.240-RXN|EC:2.4.1.240		molecular_function											owl:Class	
GO:0036089	biolink:NamedThing	cleavage furrow formation	Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.	got7fsn_ti	cleavage furrow positioning				Consider also annotating to 'establishment of contractile ring localization involved in cell cycle cytokinesis ; GO:0032188'.		bf	2012-01-10T02:41:03Z						biological_process											owl:Class	
GO:0046101	biolink:NamedThing	hypoxanthine biosynthetic process	The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.	got7fsn_ti	hypoxanthine biosynthesis|hypoxanthine formation|hypoxanthine anabolism|hypoxanthine synthesis													biological_process											owl:Class	
GO:0018610	biolink:NamedThing	dibenzofuran 4,4a-dioxygenase activity	Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+.	got7fsn_ti												MetaCyc:R606-RXN|UM-BBD_enzymeID:e0030|RHEA:42460		molecular_function											owl:Class	
GO:0075197	biolink:NamedThing	haustorium neck formation	The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	symbiont haustorium neck formation for entry into host|formation of symbiont haustorium neck for entry into host	https://github.com/geneontology/go-ontology/issues/18557			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0032295	biolink:NamedThing	ensheathment of neuronal cell bodies	The process in which satellite glial cells isolate neuronal cell bodies.	got7fsn_ti														biological_process											owl:Class	
GO:0047259	biolink:NamedThing	glucomannan 4-beta-mannosyltransferase activity	Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP.	got7fsn_ti	GDP-man-beta-mannan mannosyltransferase activity|glucomannan-synthase activity|GDP-mannose:glucomannan 1,4-beta-D-mannosyltransferase activity|glucomannan 4-b-mannosyltransferase activity											EC:2.4.1.32|MetaCyc:2.4.1.32-RXN		molecular_function											owl:Class	
GO:0061811	biolink:NamedThing	ADP-ribosyl cyclase activity	Catalysis of the reaction: NAD = cyclic ADP-ribose + nicotinamide.	got7fsn_ti							dph	2016-11-11T13:25:18Z						molecular_function											owl:Class	
GO:0035346	biolink:NamedThing	positive regulation of hypoxanthine transport	Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	positive regulation of 6-hydroxypurine transport						bf	2010-03-04T10:42:48Z						biological_process											owl:Class	
GO:0140604	biolink:NamedThing	mycofactocin biosynthetic process	The chemical reactions and pathways resulting in the formation of the coenzyme mycofactocin, a variably glycosylated small molecule electron pair carrier derived from the C-terminal valine-tyrosine dipeptide of the ribosomally translated precursor peptide MftA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20547					pg	2021-02-16T07:42:51Z						biological_process											owl:Class	
GO:0005822	biolink:NamedThing	inner plaque of spindle pole body	One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus.	got7fsn_ti														cellular_component											owl:Class	
GO:0006542	biolink:NamedThing	glutamine biosynthetic process	The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.	got7fsn_ti	glutamine anabolism|glutamine biosynthesis|glutamine synthesis|glutamine formation											MetaCyc:GLNSYN-PWY		biological_process											owl:Class	
GO:2000061	biolink:NamedThing	regulation of ureter smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.	got7fsn_ti							jl	2010-08-20T01:44:16Z						biological_process											owl:Class	
GO:0048634	biolink:NamedThing	regulation of muscle organ development	Any process that modulates the frequency, rate or extent of muscle development.	got7fsn_ti														biological_process											owl:Class	
GO:0018422	biolink:NamedThing	GDP-mannose:serine-protein mannose-1-phosphotransferase activity	Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0102193	biolink:NamedThing	protein-ribulosamine 3-kinase activity	Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine <=> ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine.	got7fsn_ti												MetaCyc:RXN-12003|EC:2.7.1.172|RHEA:48432		molecular_function											owl:Class	
GO:0055074	biolink:NamedThing	calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.	got7fsn_ti	regulation of calcium ion concentration													biological_process											owl:Class	
GO:0071496	biolink:NamedThing	cellular response to external stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-18T02:36:52Z						biological_process											owl:Class	
GO:0035798	biolink:NamedThing	2-alkenal reductase (NADP+) activity	Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+.	got7fsn_ti	NADPH:2-alkenal alpha,beta-hydrogenase activity						bf	2011-04-14T01:11:07Z						molecular_function											owl:Class	
GO:0032440	biolink:NamedThing	2-alkenal reductase [NAD(P)+] activity	Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+.	got7fsn_ti	n-alkanal:NAD(P)+ 2-oxidoreductase activity|NAD(P)H-dependent alkenal/one oxidoreductase activity											EC:1.3.1.74		molecular_function											owl:Class	
GO:0102250	biolink:NamedThing	linear malto-oligosaccharide phosphorylase activity	Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide.	got7fsn_ti												MetaCyc:RXN-12392|EC:2.4.1.1		molecular_function											owl:Class	
GO:0097018	biolink:NamedThing	renal albumin absorption	A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron.	got7fsn_ti							pr	2011-03-23T03:15:04Z						biological_process											owl:Class	
GO:0097017	biolink:NamedThing	renal protein absorption	A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).	got7fsn_ti							pr	2011-03-23T03:13:04Z						biological_process											owl:Class	
GO:0102950	biolink:NamedThing	indole-3-acetyl-valine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-valine  + ATP = H+ + indole-3-acetyl-valine + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-9083		molecular_function											owl:Class	
GO:0045237	biolink:NamedThing	CXCR1 chemokine receptor binding	Binding to a CXCR1 chemokine receptor.	got7fsn_ti	CXCR1 chemokine receptor ligand													molecular_function											owl:Class	
GO:0097045	biolink:NamedThing	phosphatidylserine exposure on blood platelet	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system.	got7fsn_ti							pr	2011-04-20T12:54:35Z						biological_process											owl:Class	
GO:0005142	biolink:NamedThing	interleukin-11 receptor binding	Binding to an interleukin-11 receptor.	got7fsn_ti	IL-11|interleukin-11 receptor ligand													molecular_function											owl:Class	
GO:0002089	biolink:NamedThing	lens morphogenesis in camera-type eye	The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.	got7fsn_ti	lens morphogenesis|lens morphogenesis in camera-style eye													biological_process											owl:Class	
GO:0004677	biolink:NamedThing	DNA-dependent protein kinase activity	DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	got7fsn_ti					This reaction requires the presence of DNA.									molecular_function											owl:Class	
GO:0047558	biolink:NamedThing	3-cyanoalanine hydratase activity	Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H(2)O + H(+).	got7fsn_ti	L-asparagine hydro-lyase activity|beta-cyanoalanine hydratase activity|beta-cyanoalanine hydrolase activity|beta-CNAla hydrolase activity|beta-CNA nitrilase activity|L-asparagine hydro-lyase (3-cyanoalanine-forming)											RHEA:15385|KEGG_REACTION:R01267|EC:4.2.1.65|MetaCyc:3-CYANOALANINE-HYDRATASE-RXN		molecular_function											owl:Class	
GO:0030708	biolink:NamedThing	germarium-derived female germ-line cyst encapsulation	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0006037	biolink:NamedThing	cell wall chitin metabolic process	The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.	got7fsn_ti	cell wall chitin metabolism													biological_process											owl:Class	
GO:1990304	biolink:NamedThing	MUB1-RAD6-UBR2 ubiquitin ligase complex	A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme.	got7fsn_ti					This complex has been identified in Saccharomyces cerevisiae (UniProt symbol P19812) - see PMID:18070918.		bhm	2014-03-03T21:54:21Z						cellular_component											owl:Class	
GO:0010487	biolink:NamedThing	thermospermine synthase activity	Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.	got7fsn_ti												EC:2.5.1.79|RHEA:30515|MetaCyc:RXN-11190		molecular_function											owl:Class	
GO:0010446	biolink:NamedThing	response to alkaline pH	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti	response to basic pH|response to alkalinity													biological_process											owl:Class	
GO:0021502	biolink:NamedThing	neural fold elevation formation	The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.	got7fsn_ti														biological_process											owl:Class	
GO:0032274	biolink:NamedThing	gonadotropin secretion	The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone.	got7fsn_ti	gonadotrophin secretion													biological_process											owl:Class	
GO:0031873	biolink:NamedThing	type 2 proteinase activated receptor binding	Binding to a type 2 proteinase activated receptor.	got7fsn_ti	type 2 proteinase activated receptor ligand													molecular_function											owl:Class	
GO:0010420	biolink:NamedThing	3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity	Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.	got7fsn_ti	polyprenyldihydroxybenzoate methyltransferase activity						sl	2015-10-28T22:12:58Z			GO:1990886	MetaCyc:RXN-9281|RHEA:44452|EC:2.1.1.114		molecular_function											owl:Class	
GO:0030352	biolink:NamedThing	inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity	Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0004850	biolink:NamedThing	uridine phosphorylase activity	Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.	got7fsn_ti	uridine:phosphate alpha-D-ribosyltransferase activity|UrdPase activity|UPase activity|UPH|pyrimidine phosphorylase activity											Reactome:R-HSA-74372|RHEA:24388|MetaCyc:URPHOS-RXN|Reactome:R-HSA-74376|EC:2.4.2.3		molecular_function											owl:Class	
GO:0098544	biolink:NamedThing	maintenance of protein complex location	Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.	got7fsn_ti							dos	2013-11-15T18:20:16Z						biological_process											owl:Class	
GO:0015171	biolink:NamedThing	amino acid transmembrane transporter activity	Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.	got7fsn_ti	amino acid/choline transmembrane transporter activity|general amino acid permease activity|amino acid permease activity|amino acid transporter activity|hydroxy/aromatic amino acid permease activity										GO:0015359	Reactome:R-HSA-375473|Reactome:R-HSA-379426|Reactome:R-HSA-379415|Reactome:R-HSA-375405|Reactome:R-HSA-352347|Reactome:R-HSA-8952726|Reactome:R-HSA-352354|Reactome:R-HSA-376200|Reactome:R-HSA-352119|Reactome:R-HSA-352103|Reactome:R-HSA-5659734|Reactome:R-HSA-352371|Reactome:R-HSA-5660694|Reactome:R-HSA-5660890|Reactome:R-HSA-5659674|Reactome:R-HSA-212642|Reactome:R-HSA-352174|Reactome:R-HSA-888592|Reactome:R-HSA-375417|Reactome:R-HSA-5659755|Reactome:R-HSA-378513|Reactome:R-HSA-352136|Reactome:R-HSA-352385|Reactome:R-HSA-352379|Reactome:R-HSA-5655702|Reactome:R-HSA-352107|Reactome:R-HSA-352029|Reactome:R-HSA-375790|Reactome:R-HSA-5660910|Reactome:R-HSA-375487|Reactome:R-HSA-5653850|Reactome:R-HSA-379432|Reactome:R-HSA-375768|Reactome:R-HSA-352232|Reactome:R-HSA-352108|Reactome:R-HSA-352059|Reactome:R-HSA-352364|Reactome:R-HSA-375770|Reactome:R-HSA-351963|Reactome:R-HSA-375776|Reactome:R-HSA-352158|Reactome:R-HSA-351987|Reactome:R-HSA-352052|Reactome:R-HSA-352191|Reactome:R-HSA-352182|Reactome:R-HSA-210439		molecular_function											owl:Class	
GO:0030729	biolink:NamedThing	acetoacetate-CoA ligase activity	Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+).	got7fsn_ti	acetoacetyl-CoA synthetase activity|acetoacetate:CoA ligase (AMP-forming)											KEGG_REACTION:R01357|RHEA:16117|Reactome:R-HSA-5694494|EC:6.2.1.16|MetaCyc:ACETOACETATE--COA-LIGASE-RXN		molecular_function											owl:Class	
GO:0018550	biolink:NamedThing	tetrachloro-p-hydroquinone reductive dehalogenase activity	Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl.	got7fsn_ti	tetrachlorohydroquinone reductive dehalogenase activity											UM-BBD_reactionID:r0314|EC:1.8.99.-		molecular_function											owl:Class	
GO:0008366	biolink:NamedThing	axon ensheathment	Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.	got7fsn_ti	nerve ensheathment|cellular axon ensheathment|cellular nerve ensheathment										GO:0042553			biological_process											owl:Class	
GO:0090380	biolink:NamedThing	seed trichome maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state.	got7fsn_ti					These processes continue to 60 DPA in Gossypium spp.		tb	2010-09-15T02:29:42Z						biological_process											owl:Class	
GO:0048530	biolink:NamedThing	fruit morphogenesis	The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant.	got7fsn_ti														biological_process											owl:Class	
GO:0005113	biolink:NamedThing	patched binding	Binding to a patched (ptc) protein, a receptor for hedgehog proteins.	got7fsn_ti	ptc binding|ptc ligand|patched ligand													molecular_function											owl:Class	
GO:0030219	biolink:NamedThing	megakaryocyte differentiation	The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.	got7fsn_ti	megakaryocyte cell differentiation													biological_process											owl:Class	
GO:0005742	biolink:NamedThing	mitochondrial outer membrane translocase complex	A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments.	got7fsn_ti	mitochondrion outer membrane translocase complex|GIP complex													cellular_component											owl:Class	
GO:0007168	biolink:NamedThing	receptor guanylyl cyclase signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	receptor guanylyl cyclase signalling pathway													biological_process											owl:Class	
GO:0016751	biolink:NamedThing	S-succinyltransferase activity	Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0016748	biolink:NamedThing	succinyltransferase activity	Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0019114	biolink:NamedThing	catechol dioxygenase activity	Catalysis of the reaction: catechol + O2 = a muconate.	got7fsn_ti												EC:1.13.11.-		molecular_function											owl:Class	
GO:0090583	biolink:NamedThing	protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-sorbitol(out) = protein cysteine + D-sorbitol-1-phosphate(in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0070695	biolink:NamedThing	FHF complex	A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).	got7fsn_ti					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.		mah	2009-06-04T03:17:29Z						cellular_component											owl:Class	
GO:0070594	biolink:NamedThing	juvenile hormone response element binding	Binding to a juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone.	got7fsn_ti	JHRE binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		mah	2009-04-28T03:31:27Z						molecular_function											owl:Class	
GO:0036505	biolink:NamedThing	prosaposin receptor activity	Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D).	got7fsn_ti	prosaposin-activated receptor activity						bf	2015-06-11T10:13:10Z						molecular_function											owl:Class	
GO:0051956	biolink:NamedThing	negative regulation of amino acid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	inhibition of amino acid transport|negative regulation of amino acid transmembrane transport|down-regulation of amino acid transport|downregulation of amino acid transport|down regulation of amino acid transport													biological_process											owl:Class	
GO:0102956	biolink:NamedThing	UDP-glucose:sinapaldehyde 4-beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + sinapoyl aldehyde = H+ + sinapaldehyde glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-92|RHEA:57712		molecular_function											owl:Class	
GO:0032406	biolink:NamedThing	MutLbeta complex binding	Binding to a MutLbeta mismatch repair complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0032404	biolink:NamedThing	mismatch repair complex binding	Binding to a mismatch repair complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0033622	biolink:NamedThing	integrin activation	The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.	got7fsn_ti	integrin complex activation|integrin complex assembly													biological_process											owl:Class	
GO:0018048	biolink:NamedThing	C-terminal peptidyl-proline amidation	The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0095		biological_process											owl:Class	
GO:0043004	biolink:NamedThing	cytoplasmic sequestering of CFTR protein	The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane.	got7fsn_ti	cytoplasmic storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein|retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm|sequestering of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm|sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm|cytoplasmic sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein)|storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm|cytoplasmic sequestering of cystic fibrosis transmembrane conductance regulator protein|cytoplasmic retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein|maintenance of CFTR protein location in cytoplasm													biological_process											owl:Class	
GO:0043002	biolink:NamedThing	negative regulation of Golgi to plasma membrane CFTR protein transport	Any process that stops, prevents, or reduces the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.	got7fsn_ti	down-regulation of Golgi to plasma membrane CFTR protein transport|down regulation of Golgi to plasma membrane CFTR protein transport|downregulation of Golgi to plasma membrane CFTR protein transport|inhibition of Golgi to plasma membrane CFTR protein transport													biological_process											owl:Class	
GO:0050250	biolink:NamedThing	retinal oxidase activity	Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2.	got7fsn_ti	retinene oxidase activity|retinal:oxygen oxidoreductase activity											EC:1.2.3.11|RHEA:22520|MetaCyc:RETINAL-OXIDASE-RXN		molecular_function											owl:Class	
GO:1990878	biolink:NamedThing	cellular response to gastrin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.	got7fsn_ti							sl	2015-10-07T17:38:14Z						biological_process											owl:Class	
GO:0032637	biolink:NamedThing	interleukin-8 production	The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-8 secretion|IL-8 production|interleukin-8 biosynthetic process										GO:0072606|GO:0042228			biological_process											owl:Class	
GO:0047870	biolink:NamedThing	discadenine synthase activity	Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase activity|S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferas|discadenine synthetase activity											KEGG_REACTION:R03726|MetaCyc:DISCADENINE-SYNTHASE-RXN|RHEA:19581|EC:2.5.1.24		molecular_function											owl:Class	
GO:0002100	biolink:NamedThing	tRNA wobble adenosine to inosine editing	The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine.	got7fsn_ti														biological_process											owl:Class	
GO:0007624	biolink:NamedThing	ultradian rhythm	The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours.	got7fsn_ti														biological_process											owl:Class	
GO:0060606	biolink:NamedThing	tube closure	Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.	got7fsn_ti							dph	2009-05-15T09:44:07Z						biological_process											owl:Class	
GO:0036261	biolink:NamedThing	7-methylguanosine cap hypermethylation	Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.	got7fsn_ti	snoRNA capping|TMG cap formation|m(7)G cap hypermethylation|hypermethylation of snoRNA cap|snRNA capping|hypermethylation of snRNA cap|2,2,7-trimethylguanosine cap formation|conversion of m(7)G to m(3)G						bf	2012-06-15T02:21:39Z						biological_process											owl:Class	
GO:0014055	biolink:NamedThing	acetylcholine secretion, neurotransmission	The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).	got7fsn_ti														biological_process											owl:Class	
GO:0006586	biolink:NamedThing	indolalkylamine metabolic process	The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.	got7fsn_ti	indolamine metabolic process|indolamine metabolism|indolalkylamine metabolism													biological_process											owl:Class	
GO:0018789	biolink:NamedThing	cyclamate sulfohydrolase activity	Catalysis of the reaction: cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate.	got7fsn_ti	cyclamate sulphohydrolase activity|cyclamate sulfamidase activity|cyclohexylsulfamate sulfamidase activity|cyclamate sulfamatase activity|cyclohexylsulfamate sulfohydrolase activity											UM-BBD_reactionID:r0755|RHEA:18481|MetaCyc:CYCLAMATE-SULFOHYDROLASE-RXN|EC:3.10.1.2|KEGG_REACTION:R02564		molecular_function											owl:Class	
GO:0016826	biolink:NamedThing	hydrolase activity, acting on acid sulfur-nitrogen bonds	Catalysis of the hydrolysis of any acid sulfur-nitrogen bond.	got7fsn_ti	hydrolase activity, acting on acid sulphur-nitrogen bonds											EC:3.10.-.-		molecular_function											owl:Class	
GO:0045257	biolink:NamedThing	succinate dehydrogenase complex (ubiquinone)	The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration.	got7fsn_ti														cellular_component											owl:Class	
GO:0150076	biolink:NamedThing	neuroinflammatory response	The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.	got7fsn_ti	neural tissue inflammatory response|nerve tissue inflammatory response|nervous tissue inflammatory response						bc	2018-07-26T12:25:34Z						biological_process											owl:Class	
GO:0071756	biolink:NamedThing	pentameric IgM immunoglobulin complex	A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.	got7fsn_ti	pentameric IgM antibody				Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0071518	biolink:NamedThing	autoinducer-2 kinase activity	Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.	got7fsn_ti	4,5-dihydroxy-pentane-2,3-dione kinase activity						mah	2010-01-06T05:08:17Z				RHEA:15377|MetaCyc:RXN0-5461		molecular_function											owl:Class	
GO:0047466	biolink:NamedThing	2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity	Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.	got7fsn_ti	2-chlorocarboxymethylenebutenolide isomerase activity|chlorodienelactone isomerase activity|2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase activity										GO:0018840	KEGG_REACTION:R04576|MetaCyc:5.2.1.10-RXN|EC:5.2.1.10|UM-BBD_reactionID:r0278|RHEA:10924		molecular_function											owl:Class	
GO:0052738	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.	got7fsn_ti												EC:1.2.5.-		molecular_function											owl:Class	
GO:0042056	biolink:NamedThing	chemoattractant activity	Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.	got7fsn_ti	attractant													molecular_function											owl:Class	
GO:0019559	biolink:NamedThing	histidine catabolic process to imidazol-5-yl-lactate	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate.	got7fsn_ti	histidine breakdown to imidazol-5-yl-lactate|histidine degradation to imidazol-5-yl-lactate											MetaCyc:HISTDEG-PWY		biological_process											owl:Class	
GO:0006548	biolink:NamedThing	histidine catabolic process	The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	got7fsn_ti	histidine breakdown|histidine catabolism|histidine degradation													biological_process											owl:Class	
GO:0070368	biolink:NamedThing	positive regulation of hepatocyte differentiation	Any process that activates or increases the rate or extent of hepatocyte differentiation.	got7fsn_ti	stimulation of hepatocyte differentiation|upregulation of hepatocyte differentiation|activation of hepatocyte differentiation|up-regulation of hepatocyte differentiation|positive regulation of liver cell differentiation|up regulation of hepatocyte differentiation													biological_process											owl:Class	
GO:0070991	biolink:NamedThing	medium-chain-acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12.	got7fsn_ti	MCAD activity						mah	2009-10-29T04:11:49Z				EC:1.3.99.-		molecular_function											owl:Class	
GO:1990322	biolink:NamedThing	collagen type XXIII trimer	A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane.	got7fsn_ti							bhm	2014-03-14T22:01:00Z						cellular_component											owl:Class	
GO:0047183	biolink:NamedThing	anthocyanin 5-aromatic acyltransferase activity	Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA.	got7fsn_ti	hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase activity											MetaCyc:RXN-7945|EC:2.3.1.153|RHEA:15661		molecular_function											owl:Class	
GO:0006295	biolink:NamedThing	nucleotide-excision repair, DNA incision, 3'-to lesion	The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage.	got7fsn_ti	nucleotide-excision repair, DNA incision, 3' to lesion													biological_process											owl:Class	
GO:0033683	biolink:NamedThing	nucleotide-excision repair, DNA incision	A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.	got7fsn_ti	nucleic acid cleavage involved in nucleotide-excision repair|DNA incision involved in nucleotide-excision repair													biological_process											owl:Class	
GO:0000132	biolink:NamedThing	establishment of mitotic spindle orientation	A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.	got7fsn_ti	orienting of mitotic spindle|establishment of spindle orientation during mitosis|establishment of spindle orientation involved in mitotic cell cycle|mitotic spindle orientation										GO:0030607|GO:0030609			biological_process											owl:Class	
GO:0034803	biolink:NamedThing	3-hydroxy-2-naphthoate 2,3-dioxygenase activity	Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate.	got7fsn_ti												UM-BBD_reactionID:r1104|EC:1.13.11.-		molecular_function											owl:Class	
GO:0018622	biolink:NamedThing	4-chlorophenylacetate 3,4-dioxygenase activity	Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+).	got7fsn_ti	4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)											KEGG_REACTION:R03306|RHEA:14689|MetaCyc:1.14.12.9-RXN|UM-BBD_reactionID:r0308|EC:1.14.12.9		molecular_function											owl:Class	
GO:0012511	biolink:NamedThing	monolayer-surrounded lipid storage body	A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.	got7fsn_ti	oilbody|oleosome|oil body|spherosome										GO:0009520	Wikipedia:Oil_body		cellular_component											owl:Class	
GO:0035539	biolink:NamedThing	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity	Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate (8-oxo-dGTP) + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate (8-oxo-dGMP) + diphosphate. 8-oxo-dGTP is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.	got7fsn_ti	8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase activity|8-oxo-7,8-dihydrodeoxyguanosine triphosphatase activity|8-oxo-7,8-dihydro-deoxyguanosine triphosphate pyrophosphatase activity|8-oxo-dGTPase activity|8-oxo-dGTP pyrophosphohydrolase activity						bf	2010-05-07T10:54:19Z				EC:3.6.1.55|Reactome:R-HSA-2395849|RHEA:31575|Reactome:R-HSA-2395869		molecular_function											owl:Class	
GO:0032840	biolink:NamedThing	intramolecular proline-rich ligand binding	Binding to a proline-rich region within the same polypeptide.	got7fsn_ti	intramolecular proline-rich region binding													molecular_function											owl:Class	
GO:0043621	biolink:NamedThing	protein self-association	Binding to a domain within the same polypeptide.	got7fsn_ti	protein self association|intramolecular protein binding|protein self binding													molecular_function											owl:Class	
GO:0047602	biolink:NamedThing	acetoacetate decarboxylase activity	Catalysis of the reaction: acetoacetate + H(+) = acetone + CO(2).	got7fsn_ti	acetoacetate carboxy-lyase (acetone-forming)|acetoacetate carboxy-lyase activity|acetoacetic acid decarboxylase activity											RHEA:19729|EC:4.1.1.4|KEGG_REACTION:R01366|MetaCyc:ACETOACETATE-DECARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0008899	biolink:NamedThing	homoserine O-succinyltransferase activity	Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA.	got7fsn_ti	homoserine O-transsuccinylase activity|homoserine succinyltransferase activity|succinyl-CoA:L-homoserine O-succinyltransferase activity											RHEA:22008|KEGG_REACTION:R01777|MetaCyc:HOMSUCTRAN-RXN|EC:2.3.1.46		molecular_function											owl:Class	
GO:0035692	biolink:NamedThing	macrophage migration inhibitory factor receptor complex	A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins.	got7fsn_ti							bf	2011-02-25T11:33:15Z						cellular_component											owl:Class	
GO:0042582	biolink:NamedThing	azurophil granule	Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.	got7fsn_ti	primary granule													cellular_component											owl:Class	
GO:0010620	biolink:NamedThing	negative regulation of transcription by transcription factor catabolism	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	got7fsn_ti														biological_process											owl:Class	
GO:0047840	biolink:NamedThing	dCTP diphosphatase activity	Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate.	got7fsn_ti	deoxycytidine-triphosphatase activity|dCTP nucleotidohydrolase activity|dCTPase activity|dCTP pyrophosphatase activity|deoxycytidine triphosphatase activity|deoxy-CTPase activity											MetaCyc:DCTP-PYROPHOSPHATASE-RXN|RHEA:22636|EC:3.6.1.12|Reactome:R-HSA-6786257		molecular_function											owl:Class	
GO:0002099	biolink:NamedThing	tRNA wobble guanine modification	The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.	got7fsn_ti														biological_process											owl:Class	
GO:0003878	biolink:NamedThing	ATP citrate synthase activity	Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA.	got7fsn_ti	ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|citric cleavage enzyme activity|ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|ATP-citric lyase activity|acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|ATP-citrate (pro-S)-lyase activity|acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|ATP-citrate (pro-S-)-lyase activity|citrate-ATP lyase activity|citrate cleavage enzyme activity|acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|ATP citrate (pro-S)-lyase activity|adenosine triphosphate citrate lyase activity				Note that this function was formerly EC:4.1.3.8.						GO:0046913	MetaCyc:ATP-CITRATE-PRO-S--LYASE-RXN|EC:2.3.3.8|MetaCyc:PWY-5172|KEGG_REACTION:R00352|RHEA:21160|Reactome:R-HSA-75848		molecular_function											owl:Class	
GO:0043408	biolink:NamedThing	regulation of MAPK cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.	got7fsn_ti	regulation of mitogen activated protein kinase cascade|regulation of mitogen-activated protein kinase cascade|regulation of mitogen activated protein kinase kinase kinase cascade|regulation of mitogen-activated protein kinase kinase kinase cascade|regulation of MAP kinase kinase kinase cascade|regulation of MAP kinase cascade|regulation of MAPKKK cascade													biological_process											owl:Class	
GO:0052586	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound.	got7fsn_ti							ai	2010-08-13T10:34:37Z				EC:1.7.5.-		molecular_function											owl:Class	
GO:0018533	biolink:NamedThing	peptidyl-cysteine acetylation	The acetylation of peptidyl-cysteine.	got7fsn_ti														biological_process											owl:Class	
GO:0030413	biolink:NamedThing	competence pheromone activity	A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence.	got7fsn_ti														molecular_function											owl:Class	
GO:0034834	biolink:NamedThing	2-mercaptobenzothiazole dioxygenase activity	Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol.	got7fsn_ti												UM-BBD_reactionID:r1177|EC:1.13.11.-		molecular_function											owl:Class	
GO:0034863	biolink:NamedThing	2,4,4-trimethyl-1-pentanol dehydrogenase activity	Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1270		molecular_function											owl:Class	
GO:0003691	biolink:NamedThing	double-stranded telomeric DNA binding	Binding to double-stranded telomere-associated DNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0060531	biolink:NamedThing	neuroendocrine cell differentiation involved in prostate gland acinus development	The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.	got7fsn_ti														biological_process											owl:Class	
GO:0099192	biolink:NamedThing	cerebellar Golgi cell to granule cell synapse	A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell.	got7fsn_ti							dos	2017-12-20T16:12:25Z						cellular_component											owl:Class	
GO:0022617	biolink:NamedThing	extracellular matrix disassembly	A process that results in the breakdown of the extracellular matrix.	got7fsn_ti														biological_process											owl:Class	
GO:0003286	biolink:NamedThing	atrial septum intermedium development	The progression of the atrial septum intermedium over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-20T10:23:52Z						biological_process											owl:Class	
GO:0042740	biolink:NamedThing	exogenous antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism.	got7fsn_ti	exogenous antibiotic breakdown|exogenous antibiotic degradation|exogenous antibiotic catabolism													biological_process											owl:Class	
GO:0044789	biolink:NamedThing	modulation by host of viral release from host cell	A process in which a host organism modulates the frequency, rate or extent of the release of a virus with which it is infected, from its cells.	got7fsn_ti							jl	2013-06-06T10:51:10Z						biological_process											owl:Class	
GO:1902186	biolink:NamedThing	regulation of viral release from host cell	Any process that modulates the frequency, rate or extent of viral release from host cell.	got7fsn_ti	regulation of viral exit|regulation of viral shedding|regulation of release of virus from host|regulation of viral release						ss	2013-06-04T03:54:03Z						biological_process											owl:Class	
GO:0099138	biolink:NamedThing	altruistic, chimeric sorocarp development	Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell.	got7fsn_ti	fully co-operative, chimeric sorocarp development													biological_process											owl:Class	
GO:0033659	biolink:NamedThing	modification by symbiont of host mitochondrion	The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0034991	biolink:NamedThing	nuclear meiotic cohesin complex	A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0030893	biolink:NamedThing	meiotic cohesin complex	A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0030771	biolink:NamedThing	N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity	Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	N-benzoyl-4-hydroxyanthranilate 4-methyltransferase activity|benzoyl-CoA:anthranilate N-benzoyltransferase|S-adenosyl-L-methionine:N-benzoyl-4-O-hydroxyanthranilate 4-O-methyltransferase activity											KEGG_REACTION:R04421|MetaCyc:2.1.1.105-RXN|EC:2.1.1.105|RHEA:17405		molecular_function											owl:Class	
GO:0008927	biolink:NamedThing	mannonate dehydratase activity	Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.	got7fsn_ti	mannonate hydrolyase activity|mannonic hydrolase activity|altronate hydrolase activity|D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)|D-mannonate hydro-lyase activity|D-mannonate hydrolyase activity|altronic hydro-lyase activity											RHEA:20097|MetaCyc:MANNONDEHYDRAT-RXN|KEGG_REACTION:R05606|EC:4.2.1.8		molecular_function											owl:Class	
GO:0061369	biolink:NamedThing	negative regulation of testicular blood vessel morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.	got7fsn_ti	negative regulation of testicular vasculature morphogenesis						dph	2010-10-27T02:47:14Z						biological_process											owl:Class	
GO:0039700	biolink:NamedThing	fusion of viral membrane with host outer nuclear membrane	Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit.	got7fsn_ti	viral primary envelope fusion with host outer nuclear membrane|fusion of viral membrane with host outer nuclear membrane involved in nuclear egress						bf	2013-11-06T15:07:46Z						biological_process											owl:Class	
GO:0099625	biolink:NamedThing	ventricular cardiac muscle cell membrane repolarization	The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.	got7fsn_ti														biological_process											owl:Class	
GO:0047229	biolink:NamedThing	13-hydroxydocosanoate 13-beta-glucosyltransferase activity	Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.	got7fsn_ti	UDPglucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity|UDP-glucose-13-hydroxydocosanoate glucosyltransferase activity|UDP-glucose:13-hydroxydocosanoic acid glucosyltransferase activity|uridine diphosphoglucose-hydroxydocosanoate glucosyltransferase activity|UDP-glucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity|13-glucosyloxydocosanoate 2'-beta-glucosyltransferase activity											EC:2.4.1.158|RHEA:22316|MetaCyc:HYDROXYDOCOSANOATE-TRANS-RXN		molecular_function											owl:Class	
GO:0019709	biolink:NamedThing	iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide	The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.	got7fsn_ti	iron incorporation into iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide											RESID:AA0310		biological_process											owl:Class	
GO:0048067	biolink:NamedThing	cuticle pigmentation	Establishment of a pattern of pigment in the cuticle of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0035484	biolink:NamedThing	adenine/adenine mispair binding	Binding to a double-stranded DNA region containing an A/A mispair.	got7fsn_ti	A/A mispair binding						bf	2010-04-23T10:54:52Z						molecular_function											owl:Class	
GO:0070898	biolink:NamedThing	RNA polymerase III preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter.	got7fsn_ti	RNA polymerase III hybrid type promoter transcriptional preinitiation complex assembly|RNA polymerase III type 1 promoter transcriptional preinitiation complex assembly|RNA polymerase III type 3 promoter transcriptional preinitiation complex assembly|RNA polymerase III transcription PIC formation|RNA polymerase III transcriptional preinitiation complex formation|RNA polymerase III type 2 promoter transcriptional preinitiation complex assembly|RNA polymerase III transcriptional preinitiation complex assembly|RNA polymerase III transcription PIC biosynthesis						mah	2010-08-19T04:16:04Z			GO:0000999|GO:0001021|GO:0001020|GO:0001043			biological_process											owl:Class	
GO:0102104	biolink:NamedThing	demethoxycurcumin synthase activity	Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O <=> demethoxycurcumin + 2 coenzyme A + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-11224		molecular_function											owl:Class	
GO:0080159	biolink:NamedThing	zygote elongation	The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana.	got7fsn_ti							dhl	2010-09-01T04:07:51Z						biological_process											owl:Class	
GO:0102331	biolink:NamedThing	heptadecanoyl-[acp] elongase/decarboxylase activity	Catalysis of the reaction: malonyl-CoA + 3 H+ + a heptodecanoyl-[acp] = octadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-13259		molecular_function											owl:Class	
GO:0102577	biolink:NamedThing	3-oxo-palmitate decarboxylase activity	Catalysis of the reaction: 3-oxopalmitic acid + H+ = 2-pentadecanone + carbon dioxide.	got7fsn_ti												EC:4.1.1.56|MetaCyc:RXN-15283		molecular_function											owl:Class	
GO:0018771	biolink:NamedThing	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity	Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate.	got7fsn_ti	(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase activity|2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity										GO:0008680	MetaCyc:MHPCHYDROL-RXN|RHEA:24789|EC:3.7.1.14|UM-BBD_reactionID:r0438		molecular_function											owl:Class	
GO:0098827	biolink:NamedThing	endoplasmic reticulum subcompartment	A distinct region of the endoplasmic reticulum.	got7fsn_ti														cellular_component											owl:Class	
GO:0110153	biolink:NamedThing	RNA NAD-cap (NMN-forming) hydrolase activity	Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+).	got7fsn_ti					This reaction specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.		kmv	2019-07-08T17:15:59Z				RHEA:60876		molecular_function											owl:Class	
GO:0038119	biolink:NamedThing	CCL19-activated CCR7 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CCL19-activated CCR7 signalling pathway						bf	2012-03-22T11:47:24Z						biological_process											owl:Class	
GO:0038118	biolink:NamedThing	C-C chemokine receptor CCR7 signaling pathway	A series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	C-C chemokine receptor CCR7 signalling pathway|CCR7 signaling pathway				This term was created to show the binding of cytokines to multiple receptor types, and vice-versa. Known agonists of chemokine receptor type 7 (CCR7) are C-C chemokines CCL19 and CCL21. Consider instead annotating to one of the child terms 'CCL19-activated CCR7 signaling pathway ; GO:0038119' and/or 'CCL21-activated CCR7 signaling pathway ; GO:0038120'.		bf	2012-03-22T11:43:57Z						biological_process											owl:Class	
GO:0030681	biolink:NamedThing	multimeric ribonuclease P complex	A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.	got7fsn_ti	multimeric RNase P complex													cellular_component											owl:Class	
GO:0061805	biolink:NamedThing	mitotic spindle elongation (spindle phase three)	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B.	got7fsn_ti	mitotic spindle elongation during anaphase|mitotic anaphase spindle elongation|mitotic spindle elongation during mitotic anaphase						dph	2016-11-06T23:09:43Z						biological_process											owl:Class	
GO:0097484	biolink:NamedThing	dendrite extension	Long distance growth of a single dendrite involved in cellular development.	got7fsn_ti							pr	2013-07-08T09:52:31Z						biological_process											owl:Class	
GO:0003108	biolink:NamedThing	negative regulation of the force of heart contraction by chemical signal	Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.	got7fsn_ti	negative regulation of the force of heart muscle contraction by chemical signal													biological_process											owl:Class	
GO:1900587	biolink:NamedThing	arugosin biosynthetic process	The chemical reactions and pathways resulting in the formation of arugosin.	got7fsn_ti	arugosin formation|arugosin biosynthesis|arugosin anabolism|arugosin synthesis						di	2012-05-15T06:48:45Z						biological_process											owl:Class	
GO:1990730	biolink:NamedThing	VCP-NSFL1C complex	A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97.	got7fsn_ti	p97-p47 complex						bf	2015-04-20T12:27:35Z						cellular_component											owl:Class	
GO:0032598	biolink:NamedThing	B cell receptor transport into immunological synapse	The directed movement of a B cell receptor into an immunological synapse.	got7fsn_ti	B cell receptor translocation into immunological synapse|BCR translocation into immunological synapse|BCR transport into immunological synapse													biological_process											owl:Class	
GO:0032597	biolink:NamedThing	B cell receptor transport into membrane raft	The directed movement of a B cell receptor into a membrane raft.	got7fsn_ti	B cell receptor transport into lipid raft|BCR transport into membrane raft|BCR translocation into membrane raft|B cell receptor translocation into membrane raft													biological_process											owl:Class	
GO:0038172	biolink:NamedThing	interleukin-33-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-33 signaling pathway|IL33 signaling pathway|interleukin-33-mediated signalling pathway|IL-33-mediated signaling pathway						bf	2012-06-12T10:57:35Z						biological_process											owl:Class	
GO:0030985	biolink:NamedThing	high molecular weight kininogen binding	Binding to a kininogen of high molecular mass.	got7fsn_ti	HK binding|HMW kininogen binding													molecular_function											owl:Class	
GO:0047701	biolink:NamedThing	beta-L-arabinosidase activity	Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol.	got7fsn_ti	beta-L-arabinoside arabinohydrolase activity|vicianosidase activity|b-L-arabinosidase activity											MetaCyc:BETA-L-ARABINOSIDASE-RXN|EC:3.2.1.88		molecular_function											owl:Class	
GO:0071041	biolink:NamedThing	antisense RNA transcript catabolic process	The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.	got7fsn_ti							krc	2009-07-29T01:39:36Z						biological_process											owl:Class	
GO:0044014	biolink:NamedThing	histone acetyltransferase activity (H2B-K5 specific)	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5).	got7fsn_ti	histone lysine N-acetyltransferase activity (H2B-K5 specific)													molecular_function											owl:Class	
GO:1990698	biolink:NamedThing	palmitoleoyltransferase activity	Catalysis of the transfer of a palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule.	got7fsn_ti							sp	2015-03-13T08:58:25Z						molecular_function											owl:Class	
GO:0045915	biolink:NamedThing	positive regulation of catecholamine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.	got7fsn_ti	upregulation of catecholamine metabolic process|activation of catecholamine metabolic process|stimulation of catecholamine metabolic process|up-regulation of catecholamine metabolic process|positive regulation of catecholamine metabolism|up regulation of catecholamine metabolic process													biological_process											owl:Class	
GO:0080116	biolink:NamedThing	glucuronoxylan glucuronosyltransferase activity	Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule.	got7fsn_ti							dhl	2009-04-27T03:33:49Z						molecular_function											owl:Class	
GO:0035527	biolink:NamedThing	3-hydroxypropionate dehydrogenase (NADP+) activity	Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH.	got7fsn_ti	3-hydroxypropanoate dehydrogenase (NADP+) activity|3-hydroxypropionate:NADP+ oxidoreductase|3-hydroxypropanoate:NADP+ oxidoreductase						bf	2010-05-05T10:55:07Z				MetaCyc:RXN-8974|RHEA:26438|KEGG_REACTION:R09289|EC:1.1.1.298		molecular_function											owl:Class	
GO:0045947	biolink:NamedThing	negative regulation of translational initiation	Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.	got7fsn_ti	down regulation of translational initiation|downregulation of translational initiation|down-regulation of translational initiation|inhibition of translational initiation													biological_process											owl:Class	
GO:0045460	biolink:NamedThing	sterigmatocystin metabolic process	The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	got7fsn_ti	sterigmatocystin metabolism													biological_process											owl:Class	
GO:0004935	biolink:NamedThing	adrenergic receptor activity	Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.	got7fsn_ti	adrenoceptor activity											Wikipedia:Adrenergic_receptor		molecular_function											owl:Class	
GO:0023025	biolink:NamedThing	MHC class Ib protein complex binding	Binding to a class Ib major histocompatibility complex.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0036373	biolink:NamedThing	L-fucose mutarotase activity	Catalysis of the reaction: alpha-L-fucose = beta-L-fucose.	got7fsn_ti	fucose 1-epimerase activity|alpha-L-fucose 1-epimerase activity|type-2 mutarotase activity						bf	2013-05-07T09:51:06Z				EC:5.1.3.29|RHEA:25580|MetaCyc:RXN0-5298		molecular_function											owl:Class	
GO:0018584	biolink:NamedThing	2,4,5-trichlorophenoxyacetic acid oxygenase activity	Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol.	got7fsn_ti												UM-BBD_reactionID:r0359|EC:1.13.99.-		molecular_function											owl:Class	
GO:1900082	biolink:NamedThing	negative regulation of arginine catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process.	got7fsn_ti	down-regulation of arginine catabolism|inhibition of arginine catabolism|inhibition of arginine catabolic process|downregulation of arginine catabolic process|inhibition of arginine degradation|negative regulation of arginine degradation|down regulation of arginine catabolism|down regulation of arginine catabolic process|down regulation of arginine breakdown|downregulation of arginine breakdown|inhibition of arginine breakdown|down-regulation of arginine breakdown|down-regulation of arginine degradation|downregulation of arginine degradation|negative regulation of arginine breakdown|down regulation of arginine degradation|down-regulation of arginine catabolic process|negative regulation of arginine catabolism|downregulation of arginine catabolism						pr	2012-02-01T04:04:45Z						biological_process											owl:Class	
GO:0098869	biolink:NamedThing	cellular oxidant detoxification	Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.	got7fsn_ti														biological_process											owl:Class	
GO:0097522	biolink:NamedThing	protein-DNA ISRE complex	A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA.	got7fsn_ti							pr	2013-10-17T14:35:07Z						cellular_component											owl:Class	
GO:2000816	biolink:NamedThing	negative regulation of mitotic sister chromatid separation	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation.	got7fsn_ti	negative regulation of mitotic chromosome separation|negative regulation of sister chromatid separation during mitosis|negative regulation of mitotic sister chromatid resolution|negative regulation of chromosome separation during mitosis						mah	2011-07-11T04:45:06Z						biological_process											owl:Class	
GO:0021793	biolink:NamedThing	chemorepulsion of branchiomotor axon	The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti	negative chemotaxis of branchiomotor axon													biological_process											owl:Class	
GO:0061643	biolink:NamedThing	chemorepulsion of axon	The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.	got7fsn_ti							dph	2014-08-29T08:35:40Z						biological_process											owl:Class	
GO:0071069	biolink:NamedThing	alpha4-beta1 integrin-thrombospondin-1 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1.	got7fsn_ti	ITGA4-ITGB1-THBS1 complex						mah	2009-11-03T04:05:35Z						cellular_component											owl:Class	
GO:0035248	biolink:NamedThing	alpha-1,4-N-acetylgalactosaminyltransferase activity	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.	got7fsn_ti	alpha-1,4-GalNAc transferase activity													molecular_function											owl:Class	
GO:0045482	biolink:NamedThing	trichodiene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene.	got7fsn_ti	trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase activity|trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming)|sesquiterpene cyclase activity|trichodiene synthetase activity											RHEA:12052|EC:4.2.3.6|KEGG_REACTION:R02306|MetaCyc:TRICHODIENE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0035201	biolink:NamedThing	leg disc anterior/posterior lineage restriction	Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0048099	biolink:NamedThing	anterior/posterior lineage restriction, imaginal disc	Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0140596	biolink:NamedThing	TOM complex	A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. TOM transports beta-barrel precursors across the outer membrane and the sorting and assembly machinery (SAM complex) inserts them into the target membrane.	got7fsn_ti	translocase of the outer mitochondrial membrane	https://github.com/geneontology/go-ontology/issues/20669					pg	2021-02-09T19:43:51Z						cellular_component											owl:Class	
GO:0030185	biolink:NamedThing	nitric oxide transport	The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1990069	biolink:NamedThing	stomatal opening	The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.	got7fsn_ti							tb	2013-03-27T21:18:48Z						biological_process											owl:Class	
GO:0004430	biolink:NamedThing	1-phosphatidylinositol 4-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+).	got7fsn_ti	phosphatidylinositol kinase activity|PI4K-alpha activity|ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase activity|PI4-kinase activity|PI4K|PtdIns-4-kinase activity|phosphatidylinositol kinase (phosphorylating) activity|PI 4-kinase activity|PI kinase activity|type II phosphatidylinositol kinase activity|phosphatidylinositol 4-kinase activity											Reactome:R-HSA-1675813|Reactome:R-HSA-1676185|MetaCyc:1-PHOSPHATIDYLINOSITOL-KINASE-RXN|RHEA:19877|Reactome:R-HSA-1675974|Reactome:R-HSA-1675780|Reactome:R-HSA-1675883|KEGG_REACTION:R03361|EC:2.7.1.67		molecular_function											owl:Class	
GO:0097389	biolink:NamedThing	chemokine (C-C motif) ligand 21 production	The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CCL21 production						pr	2012-10-23T07:56:26Z						biological_process											owl:Class	
GO:0015145	biolink:NamedThing	monosaccharide transmembrane transporter activity	Enables the transfer of a monosaccharide from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0051119	biolink:NamedThing	sugar transmembrane transporter activity	Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.	got7fsn_ti	sugar/polyol channel activity											Reactome:R-HSA-8876319|Reactome:R-HSA-8875902|Reactome:R-HSA-428779		molecular_function											owl:Class	
GO:0001639	biolink:NamedThing	PLC activating G protein-coupled glutamate receptor activity	A G protein-coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system.	got7fsn_ti	PLC activating metabotropic glutamate receptor activity|group I metabotropic glutamate receptor activity|PLC activating G-protein coupled glutamate receptor activity|Group I metabotropic glutamate receptor|phospholipase C activating metabotropic glutamate receptor activity													molecular_function											owl:Class	
GO:0140613	biolink:NamedThing	P-type manganese transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(in) = ADP + H+ + Mn2+(out) + phosphate.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20918					pg	2021-03-03T22:11:36Z				RHEA:66820		molecular_function											owl:Class	
GO:1990666	biolink:NamedThing	PCSK9-LDLR complex	A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway.	got7fsn_ti	PCSK9/LDL-R complex|PCSK9:EGF-A complex|PCSK9:low-density lipoprotein receptor complex|PCSK9.LDLR complex						bf	2015-03-02T10:19:15Z						cellular_component											owl:Class	
GO:0015491	biolink:NamedThing	cation:cation antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out).	got7fsn_ti														molecular_function											owl:Class	
GO:0075247	biolink:NamedThing	aeciospore formation	The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host.	got7fsn_ti														biological_process											owl:Class	
GO:0038200	biolink:NamedThing	ethylene receptor histidine kinase activity	Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.	got7fsn_ti							bf	2013-12-05T16:25:15Z						molecular_function											owl:Class	
GO:0038199	biolink:NamedThing	ethylene receptor activity	Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.	got7fsn_ti	C2H4 receptor activity|ethylene response sensor						bf	2013-12-05T16:06:13Z						molecular_function											owl:Class	
GO:1902405	biolink:NamedThing	mitotic actomyosin contractile ring localization	Any actomyosin contractile ring localization that is involved in mitotic cell cycle.	got7fsn_ti	contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle						jl	2013-09-12T12:28:05Z						biological_process											owl:Class	
GO:0050337	biolink:NamedThing	thiosulfate-thiol sulfurtransferase activity	Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide.	got7fsn_ti	sulfane sulfurtransferase activity|sulfane reductase activity|thiosulphate-thiol sulphurtransferase activity|glutathione-dependent thiosulfate reductase activity|thiosulfate:thiol sulfurtransferase activity											RHEA:14505|EC:2.8.1.3|MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN|Reactome:R-HSA-1655879		molecular_function											owl:Class	
GO:0090696	biolink:NamedThing	post-embryonic plant organ development	Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	got7fsn_ti							tb	2016-08-25T16:35:55Z						biological_process											owl:Class	
GO:0035347	biolink:NamedThing	negative regulation of hypoxanthine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	negative regulation of 6-hydroxypurine transport						bf	2010-03-04T10:43:53Z						biological_process											owl:Class	
GO:0033071	biolink:NamedThing	vancomycin metabolic process	The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.	got7fsn_ti	vancomycin metabolism													biological_process											owl:Class	
GO:0035796	biolink:NamedThing	ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing	A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP.	got7fsn_ti	energy coupling factor (ECF)-type ABC transporter|ATP-binding cassette (ABC) transporter complex, ECF-type|energy-coupling factor transporter				The ECF-type transporters differs from other types of ABC transporters because the substrate-binding subunit lies integral to the membrane.		bf	2011-04-11T02:02:41Z						cellular_component											owl:Class	
GO:0110104	biolink:NamedThing	mRNA alternative polyadenylation	The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).	got7fsn_ti							kmv	2018-03-27T19:26:56Z						biological_process											owl:Class	
GO:1900363	biolink:NamedThing	regulation of mRNA polyadenylation	Any process that modulates the frequency, rate or extent of mRNA polyadenylation.	got7fsn_ti	regulation of mRNA polyadenylylation|regulation of cleavage and polyadenylylation specificity factor activity						pr	2012-04-12T04:36:21Z						biological_process											owl:Class	
GO:0052785	biolink:NamedThing	cellulose catabolism by endo-processive cellulases	The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments.	got7fsn_ti	endo-processive cellulase activity						ai	2011-10-04T09:31:16Z						biological_process											owl:Class	
GO:0044743	biolink:NamedThing	protein transmembrane import into intracellular organelle	The directed movement of proteins into an intracellular organelle, across a membrane.	got7fsn_ti							jl	2012-11-07T15:37:36Z						biological_process											owl:Class	
GO:0090643	biolink:NamedThing	inflorescence phyllotactic patterning	The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem.	got7fsn_ti							tb	2015-05-05T14:25:09Z						biological_process											owl:Class	
GO:0060771	biolink:NamedThing	phyllotactic patterning	The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis.	got7fsn_ti							dph	2009-07-25T06:20:33Z						biological_process											owl:Class	
GO:0018351	biolink:NamedThing	peptidyl-cysteine esterification	The addition of an ester group to a cysteine residue in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0044458	biolink:NamedThing	motile cilium assembly	The aggregation, arrangement and bonding together of a set of components to form a motile cilium.	got7fsn_ti	nodal cilium assembly|motile primary cilium formation|motile primary cilium assembly|motile primary cilia assembly|motile primary cilia formation|nodal cilium formation						krc	2015-02-06T17:23:23Z			GO:1903887			biological_process											owl:Class	
GO:0051745	biolink:NamedThing	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.	got7fsn_ti	4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity|isopentenyl-diphosphate:NAD(P)+ oxidoreductase activity											EC:1.17.7.4|MetaCyc:ISPH2-RXN		molecular_function											owl:Class	
GO:0050342	biolink:NamedThing	tocopherol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol.	got7fsn_ti	S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase activity|gamma-tocopherol methyltransferase activity											MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN|RHEA:24012|EC:2.1.1.95		molecular_function											owl:Class	
GO:0051269	biolink:NamedThing	alpha-keto ester reductase activity	Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic.	got7fsn_ti												EC:1.2.-.-		molecular_function											owl:Class	
GO:0006163	biolink:NamedThing	purine nucleotide metabolic process	The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine nucleotide metabolism|purine metabolism|purine metabolic process													biological_process											owl:Class	
GO:0006178	biolink:NamedThing	guanine salvage	Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis.	got7fsn_ti	guanine, xanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0010350	biolink:NamedThing	cellular response to magnesium starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium.	got7fsn_ti														biological_process											owl:Class	
GO:0019102	biolink:NamedThing	male somatic sex determination	The determination of sex and sexual phenotypes in a male organism's soma.	got7fsn_ti														biological_process											owl:Class	
GO:0009401	biolink:NamedThing	phosphoenolpyruvate-dependent sugar phosphotransferase system	The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.	got7fsn_ti	PTS system													biological_process											owl:Class	
GO:0031778	biolink:NamedThing	type 2 melanin-concentrating hormone receptor binding	Binding to a type 2 melanin-concentrating hormone receptor.	got7fsn_ti	type 2 melanin-concentrating hormone receptor ligand													molecular_function											owl:Class	
GO:1902727	biolink:NamedThing	negative regulation of growth factor dependent skeletal muscle satellite cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.	got7fsn_ti							mr	2014-02-24T16:10:24Z						biological_process											owl:Class	
GO:1902723	biolink:NamedThing	negative regulation of skeletal muscle satellite cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation.	got7fsn_ti	down-regulation of satellite cell proliferation|down regulation of satellite cell proliferation|downregulation of satellite cell proliferation|inhibition of satellite cell proliferation						mr	2014-02-24T16:09:46Z						biological_process											owl:Class	
GO:0140293	biolink:NamedThing	ADP-ribosylglutamate hydrolase activity	Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose.	got7fsn_ti							pg	2018-11-22T14:36:37Z						molecular_function											owl:Class	
GO:0031084	biolink:NamedThing	BLOC-2 complex	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru.	got7fsn_ti														cellular_component											owl:Class	
GO:0044269	biolink:NamedThing	glycerol ether catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.	got7fsn_ti	glycerol ether catabolism|glycerol ether breakdown|glycerol ether degradation													biological_process											owl:Class	
GO:0034250	biolink:NamedThing	positive regulation of cellular amide metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.	got7fsn_ti	positive regulation of amide metabolism													biological_process											owl:Class	
GO:0046897	biolink:NamedThing	N-terminal peptidyl-tyrosine methylation	The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine.	got7fsn_ti												RESID:AA0338		biological_process											owl:Class	
GO:0090536	biolink:NamedThing	NoRC complex	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters.	got7fsn_ti							tb	2013-02-11T14:07:14Z						cellular_component											owl:Class	
GO:0045725	biolink:NamedThing	positive regulation of glycogen biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	got7fsn_ti	positive regulation of glycogen biosynthesis|positive regulation of glycogen formation|up regulation of glycogen biosynthetic process|positive regulation of glycogen synthesis|stimulation of glycogen biosynthetic process|positive regulation of glycogen anabolism|up-regulation of glycogen biosynthetic process|activation of glycogen biosynthetic process|upregulation of glycogen biosynthetic process													biological_process											owl:Class	
GO:0002254	biolink:NamedThing	kinin cascade	A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.	got7fsn_ti														biological_process											owl:Class	
GO:0043741	biolink:NamedThing	alpha-aminoadipate acetyltransferase activity	Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A.	got7fsn_ti	L-2-aminoadipate N-acetyltransferase activity	https://github.com/geneontology/go-ontology/issues/18958									GO:0043869	MetaCyc:RXN-5181		molecular_function											owl:Class	
GO:0090593	biolink:NamedThing	peptidyl-histidine autophosphorylation	The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein.	got7fsn_ti							tb	2014-06-06T14:19:46Z						biological_process											owl:Class	
GO:0098780	biolink:NamedThing	response to mitochondrial depolarisation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria.	got7fsn_ti														biological_process											owl:Class	
GO:0044224	biolink:NamedThing	juxtaparanode region of axon	A region of an axon near a node of Ranvier that is between the paranode and internode regions.	got7fsn_ti	juxta paranode axon|juxtaparanodal region|juxtaparanode						jl	2009-11-13T12:57:36Z				NIF_Subcellular:sao758620702		cellular_component											owl:Class	
GO:0034828	biolink:NamedThing	4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity	Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+.	got7fsn_ti												UM-BBD_reactionID:r1172		molecular_function											owl:Class	
GO:1990381	biolink:NamedThing	ubiquitin-specific protease binding	Binding to a ubiquitin-specific protease.	got7fsn_ti	deubiquitinating enzyme binding|deubiquitinase binding						bf	2014-05-19T10:01:53Z						molecular_function											owl:Class	
GO:0033437	biolink:NamedThing	ACU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an ACU codon.	got7fsn_ti	threonine tRNA|ACT codon-amino acid adaptor activity				Note that in the standard genetic code, ACT codes for threonine.									molecular_function											owl:Class	
GO:0046887	biolink:NamedThing	positive regulation of hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.	got7fsn_ti	up regulation of hormone secretion|stimulation of hormone secretion|activation of hormone secretion|upregulation of hormone secretion|up-regulation of hormone secretion													biological_process											owl:Class	
GO:0061496	biolink:NamedThing	half bridge of mitotic spindle pole body	Structure adjacent to the plaques of the mitotic spindle pole body.	got7fsn_ti							dph	2012-12-11T09:13:52Z						cellular_component											owl:Class	
GO:0010148	biolink:NamedThing	transpiration	Release of water by the plant into the air as water vapor mainly through leaves.	got7fsn_ti												Wikipedia:Transpiration		biological_process											owl:Class	
GO:0070780	biolink:NamedThing	dihydrosphingosine-1-phosphate phosphatase activity	Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.	got7fsn_ti	sphinganine-1-phosphate phosphatase activity|dihydrosphingosine-1-phosphate phosphohydrolase activity						mah	2009-07-02T02:13:49Z				RHEA:27514|MetaCyc:RXN3DJ-25|Reactome:R-HSA-428664		molecular_function											owl:Class	
GO:0048259	biolink:NamedThing	regulation of receptor-mediated endocytosis	Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.	got7fsn_ti	regulation of receptor mediated endocytosis													biological_process											owl:Class	
GO:0008800	biolink:NamedThing	beta-lactamase activity	Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.	got7fsn_ti	beta-lactamase AME I|cephalosporin-beta-lactamase activity|penicillinase I, II|neutrapen|penicillin beta-lactamase activity|exopenicillinase activity|beta-lactam hydrolase activity|penicillin amido-beta-lactamhydrolase activity|beta-lactamase A, B, C|beta-lactamase I-III|ampicillinase activity											RHEA:20401|MetaCyc:BETA-LACTAMASE-RXN|EC:3.5.2.6		molecular_function											owl:Class	
GO:0045127	biolink:NamedThing	N-acetylglucosamine kinase activity	Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+).	got7fsn_ti	acetylaminodeoxyglucokinase activity|GlcNAc kinase activity|ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity|acetylglucosamine kinase (phosphorylating)|2-acetylamino-2-deoxy-D-glucose kinase activity|ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity											RHEA:17417|EC:2.7.1.59|MetaCyc:N-ACETYLGLUCOSAMINE-KINASE-RXN|KEGG_REACTION:R01201|Reactome:R-HSA-6803771		molecular_function											owl:Class	
GO:0043724	biolink:NamedThing	2-keto-3-deoxygalactonate aldolase activity	Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate.	got7fsn_ti	KDGal aldolase activity													molecular_function											owl:Class	
GO:0047276	biolink:NamedThing	N-acetyllactosaminide 3-alpha-galactosyltransferase activity	Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.	got7fsn_ti	UDP-Gal:N-acetyllactosaminide alpha-(1,3)-galactosyltransferase activity|UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha-(1,3)-galactosyltransferase activity|alpha-galactosyltransferase activity|UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase activity|uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase activity|N-acetyllactosaminide alpha-1,3-galactosyltransferase activity|beta-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine alpha1->3-galactosyltransferase activity|uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl-glucosylceramide galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha(1,3)-galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase activity|beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine alpha-1->3-galactosyltransferase activity|UDP-Gal:Galbeta1->4GlcNAc-R alpha1->3-galactosyltransferase activity|glucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase activity|UDP-galactose:N-acetyllactosaminide 3-alpha-D-galactosyltransferase activity|UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase activity										GO:0003946	MetaCyc:2.4.1.151-RXN|EC:2.4.1.87|RHEA:13013		molecular_function											owl:Class	
GO:0010315	biolink:NamedThing	auxin efflux	The process involved in the transport of auxin out of the cell.	got7fsn_ti	auxin export													biological_process											owl:Class	
GO:0021514	biolink:NamedThing	ventral spinal cord interneuron differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0021570	biolink:NamedThing	rhombomere 4 development	The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0102477	biolink:NamedThing	2,5,7-trihydroxyflavanone 6C-glucoside dehydratase activity	Catalysis of the reaction: 6C-glucosyl-2,5,7-trihydroxyflavanone <=> H+ + 6C-hexosyl chrysin + H2O.	got7fsn_ti												MetaCyc:RXN-14088		molecular_function											owl:Class	
GO:0034538	biolink:NamedThing	3-methylsalicylaldehyde dehydrogenase activity	Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r0784		molecular_function											owl:Class	
GO:0051664	biolink:NamedThing	nuclear pore localization	Any process in which nuclear pores are transported to, or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of nuclear pore localization|nuclear pore localisation|nuclear pore distribution|positioning of nuclear pores										GO:0031081			biological_process											owl:Class	
GO:0030644	biolink:NamedThing	cellular chloride ion homeostasis	Any process involved in the maintenance of an internal steady state of chloride ions at the level of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0019029	biolink:NamedThing	helical viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure.	got7fsn_ti														cellular_component											owl:Class	
GO:0008926	biolink:NamedThing	mannitol-1-phosphate 5-dehydrogenase activity	Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.	got7fsn_ti												EC:1.1.1.17|MetaCyc:MANNPDEHYDROG-RXN|RHEA:19661		molecular_function											owl:Class	
GO:0062241	biolink:NamedThing	double strand break-nuclear membrane anchor activity	Binding to DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair.	got7fsn_ti	DNA repair factory						dph	2020-04-20T18:23:59Z						molecular_function											owl:Class	
GO:0035723	biolink:NamedThing	interleukin-15-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-15-mediated signalling pathway|IL-15-mediated signaling pathway						bf	2011-03-07T11:28:29Z						biological_process											owl:Class	
GO:0044834	biolink:NamedThing	retroviral intasome	A tetramer of retroviral integrase subunits tightly associated with a pair of viral DNA ends. Functions to insert viral DNA into a host cell chromosome.	got7fsn_ti							jl	2014-02-06T14:33:39Z						cellular_component											owl:Class	
GO:0035129	biolink:NamedThing	post-embryonic hindlimb morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0050039	biolink:NamedThing	lactaldehyde reductase (NADPH) activity	Catalysis of the reaction: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH.	got7fsn_ti	1,2-propanediol:NADP+ oxidoreductase activity|propane-1,2-diol:NADP+ oxidoreductase activity|lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADP-1,2-propanediol dehydrogenase activity|propanediol dehydrogenase activity											MetaCyc:LACTALDEHYDE-REDUCTASE-NADPH-RXN|EC:1.1.1.55|KEGG_REACTION:R02259|RHEA:15885		molecular_function											owl:Class	
GO:0042371	biolink:NamedThing	vitamin K biosynthetic process	The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.	got7fsn_ti	vitamin K biosynthesis|vitamin K synthesis|naphthoquinone metabolic process|naphthoquinone metabolism|vitamin K anabolism|vitamin K formation													biological_process											owl:Class	
GO:0046275	biolink:NamedThing	flavonoid catabolic process	The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton.	got7fsn_ti	flavonoid degradation|flavonoid catabolism|flavonoid breakdown													biological_process											owl:Class	
GO:1901575	biolink:NamedThing	organic substance catabolic process	The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.	got7fsn_ti	organic substance breakdown|organic molecular entity breakdown|organic molecular entity catabolic process|organic substance degradation|organic molecular entity degradation|organic molecular entity catabolism|organic substance catabolism						pr	2012-11-05T11:04:36Z						biological_process											owl:Class	
GO:0018174	biolink:NamedThing	protein-heme P460 linkage	The linkage of protein to heme P460.	got7fsn_ti	protein-haem P460 linkage											RESID:AA0266|RESID:AA0271		biological_process											owl:Class	
GO:0035264	biolink:NamedThing	multicellular organism growth	The increase in size or mass of an entire multicellular organism, as opposed to cell growth.	got7fsn_ti	body growth													biological_process											owl:Class	
GO:0000405	biolink:NamedThing	bubble DNA binding	Binding to DNA segment that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0016692	biolink:NamedThing	NADH peroxidase activity	Catalysis of the reaction: H(2)O(2) + H(+) + NADH = 2 H(2)O + NAD(+).	got7fsn_ti	diphosphopyridine nucleotide peroxidase activity|NADH:hydrogen-peroxide oxidoreductase activity|NADH-peroxidase activity|DPNH peroxidase activity|nicotinamide adenine dinucleotide peroxidase activity|NAD peroxidase activity											RHEA:18509|MetaCyc:NADH-PEROXIDASE-RXN|KEGG_REACTION:R00090|EC:1.11.1.1		molecular_function											owl:Class	
GO:0034583	biolink:NamedThing	21U-RNA binding	Binding to a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.	got7fsn_ti														molecular_function											owl:Class	
GO:0062213	biolink:NamedThing	peroxynitrite isomerase activity	Catalysis of the reaction: peroxynitrite = nitrate.	got7fsn_ti							dph	2020-02-22T13:57:50Z				RHEA:63116		molecular_function											owl:Class	
GO:0008180	biolink:NamedThing	COP9 signalosome	A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.	got7fsn_ti	signalosome|CSN|COP9 complex													cellular_component											owl:Class	
GO:0033705	biolink:NamedThing	GDP-4-dehydro-6-deoxy-D-mannose reductase activity	Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+.	got7fsn_ti	GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming) activity|GDP-6-deoxy-D-lyxo-4-hexulose reductase activity|GDP-4-keto-6-deoxy-D-mannose reductase activity|Rmd				Note that this enzyme differs from EC:1.1.1.187, GDP-4-dehydro-D-rhamnose reductase, in that the only product formed is GDP-D-rhamnose (GDP-6-deoxy-D-mannose).							MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN|EC:1.1.1.281		molecular_function											owl:Class	
GO:0000737	biolink:NamedThing	DNA catabolic process, endonucleolytic	The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.	got7fsn_ti	endonucleolytic DNA catabolism|DNA degradation, endonucleolytic|endonucleolytic degradation of DNA|DNA breakdown, endonucleolytic													biological_process											owl:Class	
GO:0006308	biolink:NamedThing	DNA catabolic process	The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.	got7fsn_ti	DNA breakdown|DNA degradation|DNA catabolism													biological_process											owl:Class	
GO:0102211	biolink:NamedThing	unsaturated rhamnogalacturonyl hydrolase activity	Catalysis of the reaction: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) + H2O <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + alpha-L-rhamnopyranose.	got7fsn_ti												EC:3.2.1.172|RHEA:30927|MetaCyc:RXN-12174		molecular_function											owl:Class	
GO:0021925	biolink:NamedThing	cerebellar Purkinje cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.	got7fsn_ti														biological_process											owl:Class	
GO:0043560	biolink:NamedThing	insulin receptor substrate binding	Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.	got7fsn_ti	insulin receptor substrate [protein] binding|IRS binding|IRS [protein] binding													molecular_function											owl:Class	
GO:0033153	biolink:NamedThing	T cell receptor V(D)J recombination	The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).	got7fsn_ti	T cell receptor V-D-J recombination|T cell receptor V-D-J joining|T cell receptor V-J joining|T cell receptor V-J recombination|T cell receptor V(D)J joining|T-cell receptor V(D)J recombination|TCR V(D)J recombination													biological_process											owl:Class	
GO:0033151	biolink:NamedThing	V(D)J recombination	The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).	got7fsn_ti	V(D)J joining|V-J recombination|V-J joining|V-D-J joining|V-D-J recombination											Wikipedia:V(D)J_recombination		biological_process											owl:Class	
GO:0047008	biolink:NamedThing	pregnan-21-ol dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + pregnan-21-ol = H(+) + NADPH + pregnan-21-al.	got7fsn_ti	21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|21-hydroxy steroid dehydrogenase activity|NADP-21-hydroxysteroid dehydrogenase activity|21-hydroxysteroid dehydrogenase (NADP+) activity|21-hydroxysteroid:NADP+ 21-oxidoreductase activity|21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity											EC:1.1.1.151|MetaCyc:1.1.1.151-RXN|RHEA:23712|KEGG_REACTION:R03044		molecular_function											owl:Class	
GO:1990361	biolink:NamedThing	PKM2 pyruvate kinase complex	A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013).	got7fsn_ti	PKM2 homotetramer				An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).		bhm	2014-04-17T14:16:24Z						cellular_component											owl:Class	
GO:0070556	biolink:NamedThing	TAF4B-containing transcription factor TFIID complex	A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4.	got7fsn_ti	TFIID complex, B-cell specific													cellular_component											owl:Class	
GO:0061788	biolink:NamedThing	EGF repeat binding	Binding to Epidermal Growth Factor (EGF) repeats.	got7fsn_ti	Epidermal Growth Factor repeat binding|Epidermal growth factor domain binding						dph	2016-09-08T15:22:28Z						molecular_function											owl:Class	
GO:1990791	biolink:NamedThing	dorsal root ganglion development	The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure.	got7fsn_ti	DRG development						sl	2015-07-02T22:09:54Z						biological_process											owl:Class	
GO:0098562	biolink:NamedThing	cytoplasmic side of membrane	The side of a membrane that faces the cytoplasm.	got7fsn_ti							dos	2013-12-12T11:21:30Z						cellular_component											owl:Class	
GO:0047788	biolink:NamedThing	2-coumarate reductase activity	Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD(+) = trans-2-coumarate + H(+) + NADH.	got7fsn_ti	coumarate reductase activity|3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase activity|melilotate dehydrogenase activity											MetaCyc:COUMARATE-REDUCTASE-RXN|RHEA:21444|EC:1.3.1.11|KEGG_REACTION:R03709		molecular_function											owl:Class	
GO:0000704	biolink:NamedThing	pyrimidine dimer DNA N-glycosylase activity	Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.	got7fsn_ti														molecular_function											owl:Class	
GO:0021956	biolink:NamedThing	central nervous system interneuron axonogenesis	Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.	got7fsn_ti														biological_process											owl:Class	
GO:0052589	biolink:NamedThing	malate dehydrogenase (menaquinone) activity	Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol.	got7fsn_ti	(S)-malate:menaquinone oxidoreductase activity|(S)-malate:(menaquinone) oxidoreductase activity											EC:1.1.5.4|MetaCyc:RXNI-3		molecular_function											owl:Class	
GO:0098987	biolink:NamedThing	regulation of modification of synapse structure, modulating synaptic transmission	Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:1905244	biolink:NamedThing	regulation of modification of synaptic structure	Any process that modulates the frequency, rate or extent of modification of synaptic structure.	got7fsn_ti	regulation of synapse remodelling						dos	2016-06-09T09:43:40Z						biological_process											owl:Class	
GO:0098824	biolink:NamedThing	peptidyl-cysteine sulfation	The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.	got7fsn_ti												RESID:AA0171		biological_process											owl:Class	
GO:0048755	biolink:NamedThing	branching morphogenesis of a nerve	The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).	got7fsn_ti														biological_process											owl:Class	
GO:0080079	biolink:NamedThing	cellobiose glucosidase activity	Catalysis of the reaction: cellobiose + H2O = 2 D-glucose.	got7fsn_ti	cellobiose glucohydrolase activity						dhl	2009-04-14T04:07:16Z				MetaCyc:RXN-10773		molecular_function											owl:Class	
GO:0010907	biolink:NamedThing	positive regulation of glucose metabolic process	Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.	got7fsn_ti	positive regulation of glucose metabolism													biological_process											owl:Class	
GO:0106080	biolink:NamedThing	GATOR1 complex binding	Binding to a GATOR1 complex.	got7fsn_ti							hjd	2017-12-22T14:49:54Z						molecular_function											owl:Class	
GO:0043797	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity	Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin.	got7fsn_ti	D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase activity|glyceraldehyde-3-phosphate Fd oxidoreductase activity|GAPOR|glyceraldehyde-3-phosphate ferredoxin reductase activity											EC:1.2.7.6|RHEA:24148|MetaCyc:1.2.7.6-RXN		molecular_function											owl:Class	
GO:0009385	biolink:NamedThing	N-acylmannosamine-6-phosphate 2-epimerase activity	Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate.	got7fsn_ti	N-acylmannosamine-6-P epimerase activity											EC:5.1.3.9|RHEA:25257|MetaCyc:NANE-RXN		molecular_function											owl:Class	
GO:0042814	biolink:NamedThing	monopolar cell growth	Polarized growth from one end of a cell.	got7fsn_ti	monopolar growth|polar cell elongation|monopolar cell elongation													biological_process											owl:Class	
GO:0035809	biolink:NamedThing	regulation of urine volume	Any process that modulates the amount of urine excreted from the body over a unit of time.	got7fsn_ti	regulation of urinary volume|regulation of urine flow						bf	2011-04-20T01:17:38Z						biological_process											owl:Class	
GO:1900589	biolink:NamedThing	violaceol I catabolic process	The chemical reactions and pathways resulting in the breakdown of violaceol I.	got7fsn_ti	violaceol I degradation|violaceol I catabolism|violaceol I breakdown						di	2012-05-15T06:51:09Z						biological_process											owl:Class	
GO:0102223	biolink:NamedThing	4,4'-diapophytoene desaturase activity	Catalysis of the reaction: 4 H+ + 15-cis-4,4'-diapophytoene + 4 FAD <=> 4,4'-diapolycopene + 4 FADH2.	got7fsn_ti												RHEA:31391|EC:1.3.8.2|MetaCyc:RXN-12224		molecular_function											owl:Class	
GO:0034429	biolink:NamedThing	tectobulbar tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.	got7fsn_ti														biological_process											owl:Class	
GO:0061156	biolink:NamedThing	pulmonary artery morphogenesis	The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.	got7fsn_ti							dph	2010-06-15T09:13:47Z						biological_process											owl:Class	
GO:0002779	biolink:NamedThing	antibacterial peptide secretion	The regulated release of an antibacterial peptide from a cell or a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0090001	biolink:NamedThing	replication fork arrest at tRNA locus	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit.	got7fsn_ti							tb	2009-06-24T11:36:15Z						biological_process											owl:Class	
GO:0047010	biolink:NamedThing	hydroxycyclohexanecarboxylate dehydrogenase activity	Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH.	got7fsn_ti	(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity|dihydroxycyclohexanecarboxylate dehydrogenase activity|(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity											RHEA:10516|EC:1.1.1.166|KEGG_REACTION:R05315|MetaCyc:1.1.1.166-RXN		molecular_function											owl:Class	
GO:0007278	biolink:NamedThing	pole cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0008608	biolink:NamedThing	attachment of spindle microtubules to kinetochore	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.	got7fsn_ti	microtubule and chromosome interaction|microtubule and kinetochore interaction|spindle chromosome attachment|bipolar attachment|attachment of spindle microtubules to chromosome|spindle kinetochore attachment|amphotelic attachment|microtubule capture|microtubule anchoring at kinetochore|kinetochore-microtubule attachment|kinetochore microtubule interaction|spindle-chromosome interaction|kinetochore-microtubule interaction				This class covers all attachments of spindle microtubules to the kinetochore, including the many incorrect attachments which initially form and are later corrected to stable attachments with the correct orientation for segregation to proceed (sister chromatid biorientation).						GO:0051313			biological_process											owl:Class	
GO:0043552	biolink:NamedThing	positive regulation of phosphatidylinositol 3-kinase activity	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.	got7fsn_ti	stimulation of phosphatidylinositol 3-kinase activity|upregulation of phosphatidylinositol 3-kinase activity|up regulation of phosphatidylinositol 3-kinase activity|positive regulation of phosphoinositide 3-kinase activity|activation of phosphatidylinositol 3-kinase activity|up-regulation of phosphatidylinositol 3-kinase activity													biological_process											owl:Class	
GO:0052789	biolink:NamedThing	mannan 1,3-beta-mannosidase activity	Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose.	got7fsn_ti	exo-1,3-mannanase activity|1,3-beta-D-mannan mannanohydrolase activity|exo-beta-1,3-mannase activity|beta-1,3-mannan 3-mannanohydrolase activity|exo-1,3-beta-mannanase activity						ai	2011-10-04T01:11:41Z						molecular_function											owl:Class	
GO:0030269	biolink:NamedThing	tetrahydromethanopterin S-methyltransferase activity	Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM.	got7fsn_ti	tetrahydromethanopterin methyltransferase activity|N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase activity|N5-methyltetrahydromethanopterin--coenzyme M methyltransferase activity|5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase activity										GO:0018709	UM-BBD_reactionID:r0355|RHEA:53492|KEGG_REACTION:R04347|MetaCyc:2.1.1.86-RXN|EC:2.1.1.86		molecular_function											owl:Class	
GO:0042086	biolink:NamedThing	5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin.	got7fsn_ti														molecular_function											owl:Class	
GO:0018926	biolink:NamedThing	methanesulfonic acid metabolic process	The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide.	got7fsn_ti	methanesulphonic acid metabolic process|methanesulphonic acid metabolism|methanesulfonic acid metabolism											UM-BBD_pathwayID:msa		biological_process											owl:Class	
GO:0047018	biolink:NamedThing	indole-3-acetaldehyde reductase (NADH) activity	Catalysis of the reaction: indole-3-ethanol + NAD(+) = (indol-3-yl)acetaldehyde + H(+) + NADH.	got7fsn_ti	indoleacetaldehyde reductase activity|(indol-3-yl)ethanol:NAD+ oxidoreductase activity|indole-3-ethanol:NAD+ oxidoreductase activity											EC:1.1.1.190|KEGG_REACTION:R02679|RHEA:14873|MetaCyc:1.1.1.190-RXN		molecular_function											owl:Class	
GO:0051886	biolink:NamedThing	negative regulation of timing of anagen	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.	got7fsn_ti	downregulation of anagen|down-regulation of anagen|inhibition of anagen|negative regulation of anagen|down regulation of anagen													biological_process											owl:Class	
GO:0048817	biolink:NamedThing	negative regulation of hair follicle maturation	Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation.	got7fsn_ti	downregulation of hair follicle maturation|down-regulation of hair follicle maturation|inhibition of hair follicle maturation|down regulation of hair follicle maturation													biological_process											owl:Class	
GO:0045773	biolink:NamedThing	positive regulation of axon extension	Any process that activates or increases the frequency, rate or extent of axon extension.	got7fsn_ti	up regulation of axon extension|upregulation of axon extension|stimulation of axon extension|activation of axon extension|up-regulation of axon extension													biological_process											owl:Class	
GO:0090677	biolink:NamedThing	reversible differentiation	A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another.	got7fsn_ti							tb	2016-04-28T17:32:40Z						biological_process											owl:Class	
GO:0051969	biolink:NamedThing	regulation of transmission of nerve impulse	Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.	got7fsn_ti	regulation of conduction of nerve impulse													biological_process											owl:Class	
GO:0035737	biolink:NamedThing	injection of substance in to other organism	The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes.	got7fsn_ti							bf	2011-03-17T10:58:57Z						biological_process											owl:Class	
GO:1990298	biolink:NamedThing	bub1-bub3 complex	Protein complex that associates with the kinetochores.	got7fsn_ti							al	2014-02-26T09:23:04Z						cellular_component											owl:Class	
GO:0036167	biolink:NamedThing	phenotypic switching in response to host	A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.	got7fsn_ti							bf	2012-03-27T01:44:24Z						biological_process											owl:Class	
GO:0032475	biolink:NamedThing	otolith formation	The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti														biological_process											owl:Class	
GO:0031221	biolink:NamedThing	arabinan metabolic process	The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues.	got7fsn_ti	arabinan metabolism													biological_process											owl:Class	
GO:0097454	biolink:NamedThing	Schwann cell microvillus	Small finger-like extension of a Schwann cell that contacts the nodal membrane.	got7fsn_ti							pr	2012-12-19T13:01:02Z				NIF_Subcellular:sao1890444066		cellular_component											owl:Class	
GO:0102929	biolink:NamedThing	lachrymatory factor synthase activity	Catalysis of the reaction: 1-propenylsulfenate = propanethiol S-oxide.	got7fsn_ti												MetaCyc:RXN-8911		molecular_function											owl:Class	
GO:0001014	biolink:NamedThing	snoRNA transcription by RNA polymerase III	The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter.	got7fsn_ti	snoRNA transcription from a type 2 RNA polymerase III promoter						krc	2010-08-18T07:13:45Z						biological_process											owl:Class	
GO:0048106	biolink:NamedThing	establishment of thoracic bristle planar orientation	Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.	got7fsn_ti	establishment of body bristle planar orientation													biological_process											owl:Class	
GO:0099593	biolink:NamedThing	endocytosed synaptic vesicle to endosome fusion	Fusion of an endocytosed synaptic vesicle with an endosome.	got7fsn_ti														biological_process											owl:Class	
GO:0008300	biolink:NamedThing	isoprenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	got7fsn_ti	polyisoprenoid breakdown|isoprenoid catabolism|polyisoprenoid catabolic process|isoprenoid degradation|polyisoprenoid degradation|polyisoprenoid catabolism|polyterpene catabolic process|isoprenoid breakdown|polyterpene catabolism										GO:0016097			biological_process											owl:Class	
GO:0008473	biolink:NamedThing	ornithine cyclodeaminase activity	Catalysis of the reaction: L-ornithine = L-proline + NH(4)(+).	got7fsn_ti	ornithine cyclase (deaminating) activity|ornithine cyclase activity|L-ornithine ammonia-lyase (cyclizing; L-proline-forming)|L-ornithine ammonia-lyase (cyclizing)|OCD activity				Note that cyclodeaminases are lyases according to EC, whereas deaminases are hydrolases.							KEGG_REACTION:R00671|MetaCyc:ORNITHINE-CYCLODEAMINASE-RXN|RHEA:24368|EC:4.3.1.12		molecular_function											owl:Class	
GO:0033327	biolink:NamedThing	Leydig cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.	got7fsn_ti														biological_process											owl:Class	
GO:0050832	biolink:NamedThing	defense response to fungus	Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.	got7fsn_ti	defense response to fungi|defense response to fungus, incompatible interaction|response to parasitic fungi|response to parasitic fungus|resistance response to pathogenic fungi|defence response to fungi|defence response to fungus|resistance response to pathogenic fungus										GO:0009817|GO:0042831|GO:0009623			biological_process											owl:Class	
GO:0110115	biolink:NamedThing	Cdr2 medial cortical node complex	A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase.	got7fsn_ti	interphase cortical node|interphase node						kmv	2018-07-10T14:02:26Z						cellular_component											owl:Class	
GO:0090402	biolink:NamedThing	oncogene-induced cell senescence	A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family.	got7fsn_ti	OIS						tb	2011-01-05T02:37:57Z						biological_process											owl:Class	
GO:0090398	biolink:NamedThing	cellular senescence	A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.	got7fsn_ti							tb	2011-01-05T02:27:08Z						biological_process											owl:Class	
GO:0010229	biolink:NamedThing	inflorescence development	The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0015069	biolink:NamedThing	scyllo-inosamine-4-phosphate amidinotransferase activity	Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine.	got7fsn_ti	L-arginine:inosamine-P-amidinotransferase activity|inosamine-P amidinotransferase activity|L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase activity|L-arginine:inosamine phosphate amidinotransferase activity|inosamine-phosphate amidinotransferase activity											KEGG_REACTION:R03477|MetaCyc:2.1.4.2-RXN|RHEA:13265|EC:2.1.4.2		molecular_function											owl:Class	
GO:0015067	biolink:NamedThing	amidinotransferase activity	Catalysis of the reversible transfer of an amidino group to an acceptor.	got7fsn_ti	transamidinase activity											EC:2.1.4.-		molecular_function											owl:Class	
GO:0046884	biolink:NamedThing	follicle-stimulating hormone secretion	The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.	got7fsn_ti	follicle stimulating hormone secretion|FSH secretion|follitropin secretion													biological_process											owl:Class	
GO:0050916	biolink:NamedThing	sensory perception of sweet taste	The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti	sweet taste perception													biological_process											owl:Class	
GO:0000012	biolink:NamedThing	single strand break repair	The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.	got7fsn_ti														biological_process											owl:Class	
GO:0032431	biolink:NamedThing	activation of phospholipase A2 activity	Any process that initiates the activity of the inactive enzyme phospholipase A2.	got7fsn_ti	phospholipase A2 activation													biological_process											owl:Class	
GO:0032430	biolink:NamedThing	positive regulation of phospholipase A2 activity	Any process that activates or increases the activity of the enzyme phospholipase A2.	got7fsn_ti	up-regulation of phospholipase A2 activity|up regulation of phospholipase A2 activity|activation of phospholipase A2 activity|upregulation of phospholipase A2 activity|stimulation of phospholipase A2 activity													biological_process											owl:Class	
GO:0034948	biolink:NamedThing	2,6-dihydroxypseudooxynicotine hydrolase activity	Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate.	got7fsn_ti												EC:3.7.1.-|UM-BBD_reactionID:r0482		molecular_function											owl:Class	
GO:0014894	biolink:NamedThing	response to denervation involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation.	got7fsn_ti														biological_process											owl:Class	
GO:0014877	biolink:NamedThing	response to muscle inactivity involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation.	got7fsn_ti														biological_process											owl:Class	
GO:0061447	biolink:NamedThing	endocardial cushion cell fate specification	The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	got7fsn_ti							dph	2012-03-13T09:25:56Z						biological_process											owl:Class	
GO:0030758	biolink:NamedThing	3,7-dimethylquercitin 4'-O-methyltransferase activity	Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	flavonol 4'-methyltransferase activity|flavonol 4'-O-methyltransferase activity|4'-OMT activity|S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity|3,7-dimethylquercetin 4'-O-methyltransferase activity|S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity											EC:2.1.1.83|RHEA:21832|KEGG_REACTION:R03456|MetaCyc:2.1.1.83-RXN		molecular_function											owl:Class	
GO:0120067	biolink:NamedThing	pyloric sphincter smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum.	got7fsn_ti							krc	2017-06-13T22:38:26Z						biological_process											owl:Class	
GO:0042886	biolink:NamedThing	amide transport	The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0102065	biolink:NamedThing	patchoulene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> diphosphoric acid + gamma-patchoulene.	got7fsn_ti												MetaCyc:RXN-10602		molecular_function											owl:Class	
GO:0008112	biolink:NamedThing	nicotinamide N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine.	got7fsn_ti	nicotinamide methyltransferase activity|S-adenosyl-L-methionine:nicotinamide N-methyltransferase activity											MetaCyc:NICOTINAMIDE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01269|RHEA:23884|EC:2.1.1.1|Reactome:R-HSA-5359451		molecular_function											owl:Class	
GO:0106233	biolink:NamedThing	glycosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.	got7fsn_ti	glycosome biogenesis|glycosome organisation|glycosome organization and biogenesis						hjd	2019-11-01T18:29:46Z						biological_process											owl:Class	
GO:0042203	biolink:NamedThing	toluene catabolic process	The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.	got7fsn_ti	toluene breakdown|toluene catabolism|toluene degradation													biological_process											owl:Class	
GO:0050638	biolink:NamedThing	taxadien-5-alpha-ol O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate.	got7fsn_ti	acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase activity|taxadienol acetyltransferase activity|taxadien-5a-ol O-acetyltransferase activity|taxadien-5alpha-ol O-acetyltransferase activity|acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase activity|acetyl coenzyme A:taxa-4(20),11(12)-dien-5-alpha-ol O-acetyl transferase activity|taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase activity											KEGG_REACTION:R06307|MetaCyc:2.3.1.162-RXN|RHEA:22028|EC:2.3.1.162		molecular_function											owl:Class	
GO:0102504	biolink:NamedThing	luteolinidin 5-O-glucosyltransferase activity	Catalysis of the reaction: luteolinidin + UDP-alpha-D-glucose <=> luteolinidin 5-O-glucoside + UDP + 2 H+.	got7fsn_ti												MetaCyc:RXN-14424		molecular_function											owl:Class	
GO:1990654	biolink:NamedThing	sebum secreting cell proliferation	The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum.	got7fsn_ti	sebocyte proliferation						hjd	2015-02-23T19:43:49Z						biological_process											owl:Class	
GO:0015669	biolink:NamedThing	gas transport	The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0002176	biolink:NamedThing	male germ cell proliferation	The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.	got7fsn_ti							hjd	2010-11-18T02:35:14Z						biological_process											owl:Class	
GO:0048509	biolink:NamedThing	regulation of meristem development	Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0034485	biolink:NamedThing	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate.	got7fsn_ti												MetaCyc:RXN-10036|Reactome:R-HSA-1675949|RHEA:25528		molecular_function											owl:Class	
GO:0070458	biolink:NamedThing	cellular detoxification of nitrogen compound	Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.	got7fsn_ti	cellular detoxification of nitrogenous compound													biological_process											owl:Class	
GO:0051410	biolink:NamedThing	detoxification of nitrogen compound	Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.	got7fsn_ti	nitric oxide (NO) detoxification|detoxification of nitrogenous compound													biological_process											owl:Class	
GO:0042596	biolink:NamedThing	fear response	The response of an organism to a perceived external threat.	got7fsn_ti	physiological fear response										GO:0001663			biological_process											owl:Class	
GO:0102550	biolink:NamedThing	2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 2-methyl-6-geranylgeranyl-1,4-benzoquinol <=> S-adenosyl-L-homocysteine  + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+.	got7fsn_ti												MetaCyc:RXN-14917|EC:2.1.1.295|RHEA:38007		molecular_function											owl:Class	
GO:0036362	biolink:NamedThing	ascus membrane	A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi.	got7fsn_ti							bf	2012-09-21T11:21:41Z						cellular_component											owl:Class	
GO:0097069	biolink:NamedThing	cellular response to thyroxine stimulus	A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.	got7fsn_ti	cellular response to T4 stimulus						pr	2011-06-14T05:06:48Z						biological_process											owl:Class	
GO:0043036	biolink:NamedThing	starch grain	Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.	got7fsn_ti	starch granule													cellular_component											owl:Class	
GO:0015606	biolink:NamedThing	spermidine transmembrane transporter activity	Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0047882	biolink:NamedThing	estradiol 6-beta-monooxygenase activity	Catalysis of the reaction: AH(2) + estradiol-17beta + O(2) = 6beta-hydroxyestradiol-17beta + A + H(2)O.	got7fsn_ti	estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)|estradiol 6b-hydroxylase activity|estradiol 6beta-hydroxylase activity|estradiol 6b-monooxygenase activity|estradiol 6beta-monooxygenase activity|estradiol 6-beta-hydroxylase activity											RHEA:19137|MetaCyc:ESTRADIOL-6-BETA-MONOOXYGENASE-RXN|KEGG_REACTION:R03086|EC:1.14.99.11		molecular_function											owl:Class	
GO:0140570	biolink:NamedThing	extraction of mislocalized protein from mitochondrial outer membrane	The removal of a mislocalized protein from the mitochondrial outer membrane.	got7fsn_ti	extraction of mislocalized protein from outer mitochondrion membrane	https://github.com/geneontology/go-ontology/issues/20237					pg	2020-12-15T07:37:12Z						biological_process											owl:Class	
GO:0034782	biolink:NamedThing	dimethylmalonate decarboxylase activity	Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2.	got7fsn_ti												UM-BBD_reactionID:r1031		molecular_function											owl:Class	
GO:0006749	biolink:NamedThing	glutathione metabolic process	The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.	got7fsn_ti	oxidized glutathione reduction|glutathione metabolism													biological_process											owl:Class	
GO:0102668	biolink:NamedThing	liquiritigenin,NADPH:oxygen oxidoreductase activity	Catalysis of the reaction: liquiritigenin + NADPH + O2 + H+ <=> 2,4',7-trihydroxyisoflavanone + NADP(3-) + H2O.	got7fsn_ti												EC:1.14.14.87|MetaCyc:RXN-3283|RHEA:31723		molecular_function											owl:Class	
GO:0035362	biolink:NamedThing	protein-DNA ISRE complex assembly	The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.	got7fsn_ti	protein-DNA interferon-stimulated response element complex assembly						bf	2010-03-10T10:40:09Z						biological_process											owl:Class	
GO:0018051	biolink:NamedThing	C-terminal peptidyl-tryptophan amidation	The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0098		biological_process											owl:Class	
GO:0061160	biolink:NamedThing	regulation of establishment of bipolar cell polarity regulating cell shape	Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.	got7fsn_ti							dph	2010-06-23T09:21:36Z						biological_process											owl:Class	
GO:2000100	biolink:NamedThing	regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.	got7fsn_ti							dph	2010-09-14T04:44:57Z						biological_process											owl:Class	
GO:0070999	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of gravity	The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.	got7fsn_ti							mah	2009-11-03T03:27:30Z						biological_process											owl:Class	
GO:1900567	biolink:NamedThing	chanoclavine-I aldehyde metabolic process	The chemical reactions and pathways involving chanoclavine-I aldehyde.	got7fsn_ti	chanoclavine-I aldehyde metabolism						di	2012-05-15T06:31:00Z						biological_process											owl:Class	
GO:0031318	biolink:NamedThing	detection of folic acid	The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	folic acid detection|detection of folate|folic acid sensing|folate sensing|folate detection													biological_process											owl:Class	
GO:0003730	biolink:NamedThing	mRNA 3'-UTR binding	Binding to a 3' untranslated region of an mRNA molecule.	got7fsn_ti	mRNA 3' UTR binding													molecular_function											owl:Class	
GO:0000489	biolink:NamedThing	maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0106251	biolink:NamedThing	N4-acetylcytidine amidohydrolase activity	Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate.	got7fsn_ti							hjd	2020-02-19T20:31:17Z				RHEA:62932		molecular_function											owl:Class	
GO:0009413	biolink:NamedThing	response to flooding	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water.	got7fsn_ti					Note that this term should not be confused with 'response to deep water ; GO:0030912'. Flooding refers to short-term immersion, whereas 'response to deep water ; GO:0030912' refers to standing in water throughout an organism's life cycle.									biological_process											owl:Class	
GO:0036204	biolink:NamedThing	abieta-7,13-dien-18-ol hydroxylase activity	Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O.	got7fsn_ti							bf	2012-04-24T02:37:15Z				EC:1.14.14.145|MetaCyc:RXN-12799|RHEA:26221|KEGG_REACTION:R06354		molecular_function											owl:Class	
GO:0008735	biolink:NamedThing	carnitine dehydratase activity	Catalysis of the reaction: (R)-carnitine = crotono-betaine + H(2)O.	got7fsn_ti	L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming]|L-carnitine hydro-lyase activity|L-carnitine dehydratase activity											EC:4.2.1.89|KEGG_REACTION:R01925|MetaCyc:CARNDEHYDRA-RXN|RHEA:14577		molecular_function											owl:Class	
GO:0097479	biolink:NamedThing	synaptic vesicle localization	Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of synaptic vesicle position|establishment and maintenance of synaptic vesicle localization|synaptic vesicle localisation						pr	2013-05-22T14:29:55Z						biological_process											owl:Class	
GO:0051648	biolink:NamedThing	vesicle localization	Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of vesicle localization|cytoplasmic vesicle localization|vesicle localisation													biological_process											owl:Class	
GO:0035718	biolink:NamedThing	macrophage migration inhibitory factor binding	Binding to the cytokine, macrophage migration inhibitory factor.	got7fsn_ti	MIF binding						bf	2011-03-03T04:27:16Z						molecular_function											owl:Class	
GO:0047726	biolink:NamedThing	iron-cytochrome-c reductase activity	Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+.	got7fsn_ti	iron-cytochrome c reductase activity|ferrocytochrome-c:Fe3+ oxidoreductase activity											EC:1.9.98.1|MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN|RHEA:15617		molecular_function											owl:Class	
GO:0072346	biolink:NamedThing	cADPR-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.	got7fsn_ti							mah	2010-11-10T01:10:51Z						molecular_function											owl:Class	
GO:0070860	biolink:NamedThing	RNA polymerase I core factor complex	A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.	got7fsn_ti					Note that, although this complex can be considered analogous to the mammalian transcription factor SL complex, the core factor complex does not include TBP, whereas SL1 does.		mah	2009-08-14T05:00:44Z						cellular_component											owl:Class	
GO:0034005	biolink:NamedThing	germacrene-A synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.	got7fsn_ti	GAS|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity|germacrene A synthase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity|(+)-germacrene A synthase activity|(+)-(10R)-germacrene A synthase activity											RHEA:12516|KEGG_REACTION:R07649|MetaCyc:4.2.3.23-RXN|EC:4.2.3.23		molecular_function											owl:Class	
GO:0075118	biolink:NamedThing	modulation by symbiont of host G protein-coupled receptor signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host signal transduction mediated by G-protein gamma subunit|modulation by symbiont of host G-protein coupled receptor protein signal transduction|modulation by symbiont of host signal transduction mediated by G-protein beta subunit|modulation by symbiont of host signal transduction mediated by G-protein alpha subunit				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont G protein-coupled receptor  signal transduction ; GO:0075087".						GO:0075127|GO:0075124|GO:0075121			biological_process											owl:Class	
GO:0043852	biolink:NamedThing	monomethylamine methyltransferase activity	Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3.	got7fsn_ti	MMAMT|MtmB|monomethylamine:corrinoid methyltransferase activity				This function is the first step in the pathway of methanogenesis from monomethylamine.							RHEA:26059|MetaCyc:RXN-8098|EC:2.1.1.248		molecular_function											owl:Class	
GO:0043871	biolink:NamedThing	delta1-piperideine-6-carboxylate dehydrogenase activity	Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.	got7fsn_ti	PIPOX|AmaB				This function is part of the pipecolate pathway of lysine catabolism.							MetaCyc:RXN-8162|RHEA:49476		molecular_function											owl:Class	
GO:0018299	biolink:NamedThing	iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide	The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide.	got7fsn_ti	iron incorporation into the Rieske iron-sulphur cluster via bis-L-cysteinyl bis-L-histidino diiron disulphide											RESID:AA0225		biological_process											owl:Class	
GO:0003418	biolink:NamedThing	growth plate cartilage chondrocyte differentiation	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti							dph	2009-12-22T09:00:56Z						biological_process											owl:Class	
GO:0019597	biolink:NamedThing	(R)-mandelate catabolic process to benzoate	The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate.	got7fsn_ti	(R)-mandelate degradation to benzoate|(R)-mandelate breakdown to benzoate													biological_process											owl:Class	
GO:0019596	biolink:NamedThing	mandelate catabolic process	The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.	got7fsn_ti	mandelate degradation|mandelate breakdown|mandelate catabolism													biological_process											owl:Class	
GO:1990663	biolink:NamedThing	dihydroorotate dehydrogenase (fumarate) activity	Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.	got7fsn_ti							al	2015-02-26T15:47:30Z				EC:1.3.98.1|RHEA:30059		molecular_function											owl:Class	
GO:0004152	biolink:NamedThing	dihydroorotate dehydrogenase activity	Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.	got7fsn_ti	(S)-dihydroorotate:quinone oxidoreductase activity|(DHO) dehydrogenase activity|DHOdehase activity|dihydoorotic acid dehydrogenase activity|dihydroorotate:ubiquinone oxidoreductase activity											Reactome:R-HSA-73569|EC:1.3.5.2|RHEA:18073|MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN|KEGG_REACTION:R01868		molecular_function											owl:Class	
GO:0034698	biolink:NamedThing	response to gonadotropin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.	got7fsn_ti	response to gonadotropin stimulus													biological_process											owl:Class	
GO:0030632	biolink:NamedThing	D-alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.	got7fsn_ti	D-alanine synthesis|D-alanine anabolism|D-alanine formation|D-alanine biosynthesis													biological_process											owl:Class	
GO:0044163	biolink:NamedThing	host cytoskeleton	Any of the various filamentous elements that form the internal framework of host cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the host cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the host cell. The various elements of the host cytoskeleton not only serve in the maintenance of host cellular shape but also have roles in other host cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.	got7fsn_ti							jl	2009-08-11T04:27:04Z						cellular_component											owl:Class	
GO:0044788	biolink:NamedThing	modulation by host of viral process	A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected.	got7fsn_ti							jl	2013-06-06T10:50:49Z						biological_process											owl:Class	
GO:0055116	biolink:NamedThing	entry into reproductive diapause	The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	got7fsn_ti														biological_process											owl:Class	
GO:0150137	biolink:NamedThing	interleukin-37 production	The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-37 biosynthetic process						bc	2019-12-08T08:43:09Z						biological_process											owl:Class	
GO:1900733	biolink:NamedThing	negative regulation of polyketide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process.	got7fsn_ti	inhibition of polyketide formation|down regulation of polyketide synthesis|down-regulation of polyketide synthesis|negative regulation of polyketide anabolism|negative regulation of polyketide biosynthesis|downregulation of polyketide biosynthesis|down-regulation of polyketide biosynthetic process|downregulation of polyketide biosynthetic process|down-regulation of polyketide anabolism|down-regulation of polyketide formation|inhibition of polyketide biosynthesis|inhibition of polyketide biosynthetic process|downregulation of polyketide synthesis|down regulation of polyketide anabolism|down regulation of polyketide formation|negative regulation of polyketide synthesis|downregulation of polyketide anabolism|inhibition of polyketide anabolism|downregulation of polyketide formation|down-regulation of polyketide biosynthesis|inhibition of polyketide synthesis|negative regulation of polyketide formation|down regulation of polyketide biosynthesis|down regulation of polyketide biosynthetic process						di	2012-05-26T01:30:02Z						biological_process											owl:Class	
GO:0090071	biolink:NamedThing	negative regulation of ribosome biogenesis	Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.	got7fsn_ti							tb	2009-09-11T10:32:17Z						biological_process											owl:Class	
GO:0090117	biolink:NamedThing	endosome to lysosome transport of low-density lipoprotein particle	The directed movement of low-density lipoprotein particle from endosomes to lysosomes.	got7fsn_ti	endosome to lysosome transport of LDL						tb	2009-12-07T12:04:34Z						biological_process											owl:Class	
GO:0008333	biolink:NamedThing	endosome to lysosome transport	The directed movement of substances from endosomes to lysosomes.	got7fsn_ti														biological_process											owl:Class	
GO:0050292	biolink:NamedThing	steroid 9-alpha-monooxygenase activity	Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O.	got7fsn_ti	steroid 9-alpha-hydroxylase activity|steroid 9a-monooxygenase activity|steroid 9alpha-hydroxylase activity|steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing)|steroid 9alpha-monooxygenase activity											RHEA:19557|EC:1.14.99.24|MetaCyc:STEROID-9-ALPHA-MONOOXYGENASE-RXN|KEGG_REACTION:R04392		molecular_function											owl:Class	
GO:0071430	biolink:NamedThing	pre-miRNA-containing ribonucleoprotein complex export from nucleus	The directed movement of a ribonucleoprotein complex that contains pre-microRNA from the nucleus to the cytoplasm.	got7fsn_ti	pre-microRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|pre-microRNA-containing ribonucleoprotein complex nucleus export|pre-microRNA-containing RNP export from nucleus|pre-microRNA-containing ribonucleoprotein complex export from nucleus|pre-microRNA-containing ribonucleoprotein complex export from cell nucleus						mah	2009-12-16T10:26:16Z						biological_process											owl:Class	
GO:0046563	biolink:NamedThing	methanol oxidase activity	Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde.	got7fsn_ti					Note that EC:1.1.3.31 was deleted from EC as it cannot be distinguished from alcohol oxidase (EC:1.1.3.13).							MetaCyc:METHANOL-OXIDASE-RXN|EC:1.1.3.-		molecular_function											owl:Class	
GO:0018579	biolink:NamedThing	protocatechuate 4,5-dioxygenase activity	Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.	got7fsn_ti	protocatechuic 4,5-oxygenase activity|protocatechuic 4,5-dioxygenase activity|protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)|protocatechuate 4,5-oxygenase activity											UM-BBD_reactionID:r0144|RHEA:24044|MetaCyc:PROTOCATECHUATE-45-DIOXYGENASE-RXN|EC:1.13.11.8		molecular_function											owl:Class	
GO:0039643	biolink:NamedThing	host cell viral nucleoid	The region of a host cell that contains the viral genome.	got7fsn_ti					To annotate the region of the complete virus particle in which the viral genome is contained, instead use 'virion nucleoid ; GO:0039642'.		bf	2012-09-07T15:41:18Z						cellular_component											owl:Class	
GO:0035553	biolink:NamedThing	oxidative single-stranded RNA demethylation	Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.	got7fsn_ti	oxidative ssRNA demethylation						bf	2010-05-14T11:05:17Z						biological_process											owl:Class	
GO:0035370	biolink:NamedThing	UBC13-UEV1A complex	A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A).	got7fsn_ti							bf	2010-03-11T10:53:09Z						cellular_component											owl:Class	
GO:0060329	biolink:NamedThing	cytoplasmic actin-based contraction involved in rearward cell motility	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell.	got7fsn_ti	cytoplasmic actin-based contraction involved in rearward cell locomotion													biological_process											owl:Class	
GO:0070636	biolink:NamedThing	nicotinic acid riboside hydrolase activity	Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.	got7fsn_ti	nicotinate riboside hydrolase activity|D-ribosylnicotinate hydrolase activity|nicotinate ribonucleoside hydrolase activity|D-ribosylnicotinic acid hydrolase activity|nicotinic acid ribonucleoside hydrolase activity						mah	2009-05-07T02:12:00Z						molecular_function											owl:Class	
GO:0036489	biolink:NamedThing	neuromelanin biosynthetic process	The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers.	got7fsn_ti	neuromelanin formation|neuromelanin anabolism|neuromelanin biosynthesis|neuromelanin synthesis						bf	2014-11-06T13:21:46Z						biological_process											owl:Class	
GO:0016320	biolink:NamedThing	endoplasmic reticulum membrane fusion	The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum.	got7fsn_ti	ER membrane fusion													biological_process											owl:Class	
GO:0098583	biolink:NamedThing	learned vocalization behavior	A vocalization behavior that is the result of learning.	got7fsn_ti					Examples include human speech and learned bird song.		dos	2014-01-24T12:48:57Z						biological_process											owl:Class	
GO:0098598	biolink:NamedThing	learned vocalization behavior or vocal learning	Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned.	got7fsn_ti					This grouping term is necessary because, in the absence of conditional mutations, it is not possible to use phenotypic evidence to distinguish an effect on vocal learning from an effect on learned vocalisation behavior.		dos	2014-04-10T11:34:33Z						biological_process											owl:Class	
GO:0120192	biolink:NamedThing	tight junction assembly	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.	got7fsn_ti	occluding junction assembly|occluding cell junction assembly						krc	2018-08-14T22:48:05Z						biological_process											owl:Class	
GO:0007043	biolink:NamedThing	cell-cell junction assembly	The aggregation, arrangement and bonding together of a set of components to form a junction between cells.	got7fsn_ti	intercellular junction assembly													biological_process											owl:Class	
GO:0005868	biolink:NamedThing	cytoplasmic dynein complex	Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.	got7fsn_ti	cytoplasmic dynein heavy chain|cytoplasmic dynein intermediate chain|cytoplasmic dynein light chain|cytoplasmic dynein intermediate light chain				Note that this term is labelled based on phylogenetic classification and community usage, rather than strict cellular localization. Cytoplasmic dynein complexes may contain ciliary dyneins; therefore the term is not linked to 'cytoplasm'. Cytoplasmic dynein complexes do not contain axonemal dyneins; see GO:0005858 axonemal dynein complex.									cellular_component											owl:Class	
GO:0140062	biolink:NamedThing	5-formylcytosine dioxygenase activity	Catalysis of the reaction: 5-formylcytosine+ 2-oxoglutarate + O2 = 5-carboxylcytosine + succinate + CO2.	got7fsn_ti	5fC dioxygenase						pg	2017-07-20T09:57:16Z						molecular_function											owl:Class	
GO:0103055	biolink:NamedThing	gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A15 + 2-oxoglutarate + O2 <=> gibberellin A24 + succinate + carbon dioxide + H2O.	got7fsn_ti												MetaCyc:RXN1F-163|RHEA:60780		molecular_function											owl:Class	
GO:0043718	biolink:NamedThing	2-hydroxymethylglutarate dehydrogenase activity	Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD(+) = 2-formylglutarate + H(+) + NADH.	got7fsn_ti	(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity|HgD											MetaCyc:1.1.1.291-RXN|RHEA:15505|KEGG_REACTION:R07985|Wikipedia:2-hydroxymethylglutarate_dehydrogenase|EC:1.1.1.291		molecular_function											owl:Class	
GO:0052313	biolink:NamedThing	modulation of nutrient release from other organism involved in symbiotic interaction	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation of nutrient release from other organism during symbiotic interaction													biological_process											owl:Class	
GO:0033190	biolink:NamedThing	solanapyrone synthase activity	Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A.	got7fsn_ti														molecular_function											owl:Class	
GO:0005169	biolink:NamedThing	neurotrophin TRKB receptor binding	Binding to a neurotrophin TRKB receptor.	got7fsn_ti	neurotrophin TRKB receptor ligand													molecular_function											owl:Class	
GO:0032289	biolink:NamedThing	central nervous system myelin formation	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.	got7fsn_ti	myelin formation in central nervous system													biological_process											owl:Class	
GO:0004375	biolink:NamedThing	glycine dehydrogenase (decarboxylating) activity	Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2.	got7fsn_ti	glycine cleavage system P-protein activity|glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)|protein P1|glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)|glycine-cleavage complex|P-protein|glycine-cleavage complex P-protein activity|glycine decarboxylase activity											EC:1.4.4.2|Reactome:R-HSA-5693967|MetaCyc:GCVP-RXN|RHEA:24304		molecular_function											owl:Class	
GO:0090113	biolink:NamedThing	regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis	The GTP hydrolysis process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles.	got7fsn_ti							tb	2009-12-06T09:16:14Z						biological_process											owl:Class	
GO:0060628	biolink:NamedThing	regulation of ER to Golgi vesicle-mediated transport	Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.	got7fsn_ti							dph	2009-05-18T02:37:00Z						biological_process											owl:Class	
GO:0000340	biolink:NamedThing	RNA 7-methylguanosine cap binding	Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.	got7fsn_ti	RNA m7G cap binding													molecular_function											owl:Class	
GO:0061437	biolink:NamedThing	renal system vasculature development	The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.	got7fsn_ti							dph	2012-03-08T12:16:24Z						biological_process											owl:Class	
GO:0047856	biolink:NamedThing	dihydrocoumarin hydrolase activity	Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+).	got7fsn_ti	dihydrocoumarin lactonohydrolase activity|dihydrocoumarin lipase activity											KEGG_REACTION:R03692|RHEA:10360|EC:3.1.1.35|MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN		molecular_function											owl:Class	
GO:0036331	biolink:NamedThing	avascular cornea development in camera-type eye	The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees.	got7fsn_ti	avascular cornea development						bf	2012-09-05T09:07:14Z						biological_process											owl:Class	
GO:0045483	biolink:NamedThing	aristolochene synthase activity	Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.	got7fsn_ti	sesquiterpene cyclase activity|trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)|trans,trans-farnesyl diphosphate aristolochene-lyase activity											MetaCyc:ARISTOLOCHENE-SYNTHASE-RXN|RHEA:19825|EC:4.2.3.9		molecular_function											owl:Class	
GO:0015035	biolink:NamedThing	protein-disulfide reductase activity	Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.	got7fsn_ti	haem lyase disulphide oxidoreductase activity|peptide disulfide oxidoreductase activity|protein disulfide oxidoreductase activity|protein disulphide oxidoreductase activity|peptide disulphide oxidoreductase activity|protein disulfide-oxidoreductase activity|heme lyase disulfide oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/20219									GO:0008895|GO:0015037	Reactome:R-HSA-3299753|MetaCyc:DISULFOXRED-RXN|Reactome:R-HSA-1307802		molecular_function											owl:Class	
GO:0008765	biolink:NamedThing	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate.	got7fsn_ti	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)|UDP-N-acetylmuramyl-tripeptide synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase activity|MurE synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming) activity											RHEA:23676|KEGG_REACTION:R02788|EC:6.3.2.13|MetaCyc:UDP-NACMURALGLDAPLIG-RXN		molecular_function											owl:Class	
GO:0043230	biolink:NamedThing	extracellular organelle	Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.	got7fsn_ti														cellular_component											owl:Class	
GO:0034479	biolink:NamedThing	phosphatidylglycerol phospholipase C activity	Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0046570	biolink:NamedThing	methylthioribulose 1-phosphate dehydratase activity	Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O.	got7fsn_ti	1-PMT-ribulose dehydratase activity|methylthioribulose-1-phosphate dehydratase activity|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]|5-methylthioribulose-1-phosphate 4-dehydratase activity|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase[5-(methylthio)-2,3-dioxopentyl-phosphate-forming]|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase activity										GO:0043809	KEGG_REACTION:R07392|MetaCyc:R145-RXN|Reactome:R-HSA-1237140|EC:4.2.1.109|RHEA:15549		molecular_function											owl:Class	
GO:0097467	biolink:NamedThing	type III terminal bouton	Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones.	got7fsn_ti	type III terminal button						pr	2013-02-06T09:39:18Z						cellular_component											owl:Class	
GO:0007204	biolink:NamedThing	positive regulation of cytosolic calcium ion concentration	Any process that increases the concentration of calcium ions in the cytosol.	got7fsn_ti	cytoplasmic calcium ion concentration elevation|elevation of cytoplasmic calcium ion concentration|elevation of calcium ion concentration in cytosol|cytosolic calcium ion concentration elevation|elevation of calcium ion concentration in cytoplasm|elevation of cytosolic calcium ion concentration													biological_process											owl:Class	
GO:0047152	biolink:NamedThing	methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity	Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide.	got7fsn_ti	methanol-corrinoid protein Co-methyltransferase|methanol:5-hydroxybenzimidazolylcobamide methyltransferase activity|MT 1|methanol cobalamin methyltransferase activity|methyltransferase 1|methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase activity|methanol:corrinoid methyltransferase activity|MT1|MtaB				This function is the first step in the pathway of methanogenesis from methanol.						GO:1990087	MetaCyc:2.1.1.90-RXN|RHEA:21344|EC:2.1.1.90		molecular_function											owl:Class	
GO:0010266	biolink:NamedThing	response to vitamin B1	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.	got7fsn_ti	response to thiamine|response to thiamin													biological_process											owl:Class	
GO:0051643	biolink:NamedThing	endoplasmic reticulum localization	Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	ER localization|endoplasmic reticulum localisation|establishment and maintenance of ER localization													biological_process											owl:Class	
GO:1900510	biolink:NamedThing	negative regulation of pentose catabolic process to ethanol	Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol.	got7fsn_ti	down-regulation of pentose catabolism to ethanol|down regulation of pentose catabolism to ethanol|down-regulation of pentose catabolic process to ethanol|negative regulation of pentose catabolism to ethanol|downregulation of pentose catabolic process to ethanol|inhibition of pentose catabolism to ethanol|downregulation of pentose catabolism to ethanol|down regulation of pentose catabolic process to ethanol|inhibition of pentose catabolic process to ethanol						tt	2012-05-02T04:04:51Z						biological_process											owl:Class	
GO:0050868	biolink:NamedThing	negative regulation of T cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.	got7fsn_ti	downregulation of T cell activation|down-regulation of T cell activation|negative regulation of T lymphocyte activation|down regulation of T cell activation|negative regulation of T-cell activation|negative regulation of T-lymphocyte activation|inhibition of T cell activation													biological_process											owl:Class	
GO:0047315	biolink:NamedThing	kynurenine-glyoxylate transaminase activity	Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.	got7fsn_ti	kynurenine-glyoxylate aminotransferase activity|kynurenine--glyoxylate aminotransferase activity|L-kynurenine:glyoxylate aminotransferase (cyclizing)											EC:2.6.1.63|KEGG_REACTION:R01957|MetaCyc:2.6.1.63-RXN|RHEA:19249		molecular_function											owl:Class	
GO:0036137	biolink:NamedThing	kynurenine aminotransferase activity	Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid.	got7fsn_ti	L-kynurenine transaminase activity|kynurenine-oxo-acid transaminase activity						bf	2012-03-06T02:16:48Z						molecular_function											owl:Class	
GO:0042935	biolink:NamedThing	achromobactin transport	The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0050164	biolink:NamedThing	oxoglutarate dehydrogenase (NADP+) activity	Catalysis of the reaction: 2-oxoglutarate + CoA + NADP(+) = CO(2) + NADPH + succinyl-CoA.	got7fsn_ti	2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating)											EC:1.2.1.52|RHEA:21400|MetaCyc:OXOGLUTARATE-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R00265		molecular_function											owl:Class	
GO:0034601	biolink:NamedThing	oxoglutarate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H.	got7fsn_ti												EC:1.2.1.52		molecular_function											owl:Class	
GO:0102971	biolink:NamedThing	phosphinothricin N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + phosphinothricin <=> H+ + coenzyme A(4-) + N-acetylphosphinatothricinate.	got7fsn_ti												RHEA:12597|MetaCyc:RXN-9382|EC:2.3.1.183		molecular_function											owl:Class	
GO:0034839	biolink:NamedThing	menth-2-enone hydratase activity	Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone.	got7fsn_ti												UM-BBD_reactionID:r1184		molecular_function											owl:Class	
GO:0098653	biolink:NamedThing	centromere clustering	The process by which centromeres/kinetochores become localized to clusters.	got7fsn_ti	kinetochore clustering				As inner kinetochores are an integral part of centromeres, we treat centromere and kinetochore clustering as the same process.		dos	2014-05-23T19:03:37Z			GO:0098587			biological_process											owl:Class	
GO:0019166	biolink:NamedThing	trans-2-enoyl-CoA reductase (NADPH) activity	Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+.	got7fsn_ti	reductase, trans-enoyl coenzyme A|acyl-CoA:NADP+ trans-2-oxidoreductase activity|NADPH-dependent trans-2-enoyl-CoA reductase activity											Reactome:R-HSA-6786720|Reactome:R-HSA-8952873|Reactome:R-HSA-6809810|RHEA:33763|EC:1.3.1.38|MetaCyc:TRANSENOYLCOARED-RXN		molecular_function											owl:Class	
GO:0005847	biolink:NamedThing	mRNA cleavage and polyadenylation specificity factor complex	A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.	got7fsn_ti	CPF complex|cleavage and polyadenylylation specificity factor activity|CFII complex|CPSF complex													cellular_component											owl:Class	
GO:0005849	biolink:NamedThing	mRNA cleavage factor complex	Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.	got7fsn_ti														cellular_component											owl:Class	
GO:0031961	biolink:NamedThing	cortisol receptor binding	Binding to a cortisol receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0035259	biolink:NamedThing	glucocorticoid receptor binding	Binding to a glucocorticoid receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0018894	biolink:NamedThing	dibenzo-p-dioxin metabolic process	The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.	got7fsn_ti	dibenzo-p-dioxin metabolism|phenodioxin metabolic process|phenodioxin metabolism|oxanthrene metabolism|oxanthrene metabolic process											UM-BBD_pathwayID:dpd		biological_process											owl:Class	
GO:0005199	biolink:NamedThing	structural constituent of cell wall	The action of a molecule that contributes to the structural integrity of a cell wall.	got7fsn_ti														molecular_function											owl:Class	
GO:0030999	biolink:NamedThing	linear element assembly	The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex.	got7fsn_ti	linear element formation													biological_process											owl:Class	
GO:0044384	biolink:NamedThing	host outer membrane	The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites, occurring in a host cell.	got7fsn_ti	host cell outer membrane				This term covers the outer membrane of the host cell envelope or the outer membrane of a host organelle. For the outer layer of the host cell envelope specifically, see host cell outer membrane ; GO:0039662.		jl	2011-12-13T04:02:07Z						cellular_component											owl:Class	
GO:0047172	biolink:NamedThing	shikimate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA.	got7fsn_ti	shikimate hydroxycinnamoyltransferase activity|4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity											EC:2.3.1.133|RHEA:12124|MetaCyc:2.3.1.133-RXN		molecular_function											owl:Class	
GO:0008346	biolink:NamedThing	larval walking behavior	The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.	got7fsn_ti	larval walking behaviour													biological_process											owl:Class	
GO:0035283	biolink:NamedThing	central nervous system segmentation	Division of the central nervous system into a series of semi-repetitive parts or segments.	got7fsn_ti														biological_process											owl:Class	
GO:0102001	biolink:NamedThing	isoleucine N-monooxygenase (oxime forming) activity	Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.	got7fsn_ti												RHEA:28602|MetaCyc:1.14.13.117-RXN|EC:1.14.14.39		molecular_function											owl:Class	
GO:0050617	biolink:NamedThing	15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity	Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.	got7fsn_ti	PebA											EC:1.3.7.2|RHEA:10168|MetaCyc:1.3.7.2-RXN		molecular_function											owl:Class	
GO:0061919	biolink:NamedThing	process utilizing autophagic mechanism	A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.	got7fsn_ti							dph	2017-07-13T19:42:14Z						biological_process											owl:Class	
GO:0010385	biolink:NamedThing	double-stranded methylated DNA binding	Binding to double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.	got7fsn_ti														molecular_function											owl:Class	
GO:0044203	biolink:NamedThing	host cell nuclear lamina	The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments.	got7fsn_ti							jl	2009-10-21T11:11:56Z						cellular_component											owl:Class	
GO:0006588	biolink:NamedThing	activation of tryptophan 5-monooxygenase activity	The process in which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity.	got7fsn_ti	tryptophan hydroxylase activation													biological_process											owl:Class	
GO:0032770	biolink:NamedThing	positive regulation of monooxygenase activity	Any process that activates or increases the activity of a monooxygenase.	got7fsn_ti	activation of monooxygenase activity|up-regulation of monooxygenase activity|stimulation of monooxygenase activity|up regulation of monooxygenase activity|upregulation of monooxygenase activity													biological_process											owl:Class	
GO:0102858	biolink:NamedThing	1-18:2-2-18:3-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:2-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8325		molecular_function											owl:Class	
GO:0047554	biolink:NamedThing	2-pyrone-4,6-dicarboxylate lactonase activity	Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H(+).	got7fsn_ti	2-pyrone-4,6-dicarboxylate lactonohydrolase activity											EC:3.1.1.57|KEGG_REACTION:R04277|RHEA:10644|MetaCyc:RXN-2462		molecular_function											owl:Class	
GO:0043980	biolink:NamedThing	histone H2B-K12 acetylation	The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone.	got7fsn_ti	histone H2B acetylation at K12													biological_process											owl:Class	
GO:0035199	biolink:NamedThing	salt aversion	The specific avoidance actions or reactions of an organism in response to the perception of salt.	got7fsn_ti	behavioral response to salt													biological_process											owl:Class	
GO:1990384	biolink:NamedThing	hyaloid vascular plexus regression	The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression.	got7fsn_ti							hjd	2014-05-28T18:43:21Z						biological_process											owl:Class	
GO:0009038	biolink:NamedThing	undecaprenol kinase activity	Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate.	got7fsn_ti	ATP:undecaprenol phosphotransferase activity|C55-isoprenyl alcohol phosphokinase activity|C55-isoprenoid alcohol phosphokinase activity|isoprenoid alcohol kinase activity|C55-isoprenoid alcohol kinase activity|isoprenoid alcohol phosphokinase activity|polyisoprenol kinase activity|isoprenoid-alcohol kinase activity|isoprenoid alcohol kinase (phosphorylating)											EC:2.7.1.66		molecular_function											owl:Class	
GO:0004574	biolink:NamedThing	oligo-1,6-glucosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose.	got7fsn_ti	limit dextrinase|exo-oligo-1,6-glucosidase activity|sucrase-isomaltase activity|alpha-limit dextrinase activity|dextrin 6alpha-glucanohydrolase activity|isomaltase activity|oligosaccharide alpha-1,6-glucohydrolase activity|alpha-methylglucosidase activity|oligosaccharide alpha-1,6-glucosidase activity|dextrin 6-glucanohydrolase activity											EC:3.2.1.10|MetaCyc:3.2.1.10-RXN		molecular_function											owl:Class	
GO:0072555	biolink:NamedThing	17-beta-ketosteroid reductase activity	Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.	got7fsn_ti	7beta-ketosteroid reductase activity|17-beta-ketosteroid reductase (NADPH) activity						mah	2011-01-27T11:36:14Z						molecular_function											owl:Class	
GO:0034514	biolink:NamedThing	mitochondrial unfolded protein response	The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.	got7fsn_ti	mtUPR													biological_process											owl:Class	
GO:0031774	biolink:NamedThing	leukotriene receptor binding	Binding to a leukotriene receptor.	got7fsn_ti	leukotriene receptor ligand													molecular_function											owl:Class	
GO:1902181	biolink:NamedThing	verruculogen biosynthetic process	The chemical reactions and pathways resulting in the formation of verruculogen.	got7fsn_ti	verruculogen synthesis|verruculogen formation|verruculogen anabolism|verruculogen biosynthesis						di	2013-05-30T17:44:35Z						biological_process											owl:Class	
GO:0047498	biolink:NamedThing	calcium-dependent phospholipase A2 activity	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.	got7fsn_ti	calcium-dependent cytosolic phospholipase A2 activity|calcium-dependent secreted phospholipase A2 activity											Reactome:R-HSA-111883		molecular_function											owl:Class	
GO:0018037	biolink:NamedThing	C-terminal peptidyl-aspartic acid amidation	The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0084		biological_process											owl:Class	
GO:0018302	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulphide											RESID:AA0284		biological_process											owl:Class	
GO:0006896	biolink:NamedThing	Golgi to vacuole transport	The directed movement of substances from the Golgi to the vacuole.	got7fsn_ti	Golgi to vacuole vesicle-mediated transport													biological_process											owl:Class	
GO:0046974	biolink:NamedThing	histone methyltransferase activity (H3-K9 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of a methyl group onto lysine at position 9 of the histone H3 protein.	got7fsn_ti	histone lysine N-methyltransferase activity (H3-K9 specific)|histone methylase activity (H3-K9 specific)											Reactome:R-HSA-427336|Reactome:R-HSA-427527		molecular_function											owl:Class	
GO:0061976	biolink:NamedThing	temporomandibular joint articular cartilage development	The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure.	got7fsn_ti							dph	2018-02-12T20:01:00Z						biological_process											owl:Class	
GO:0061975	biolink:NamedThing	articular cartilage development	The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure.	got7fsn_ti	articular cartilage of joint development						dph	2018-02-12T19:57:31Z						biological_process											owl:Class	
GO:0047774	biolink:NamedThing	cis-2-enoyl-CoA reductase (NADPH) activity	Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH.	got7fsn_ti	NADPH-dependent cis-enoyl-CoA reductase activity|reductase, cis-2-enoyl coenzyme A|acyl-CoA:NADP+ cis-2-oxidoreductase activity|cis-2-enoyl-coenzyme A reductase activity											MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-NADPH-RXN|EC:1.3.1.37		molecular_function											owl:Class	
GO:0003879	biolink:NamedThing	ATP phosphoribosyltransferase activity	Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.	got7fsn_ti	phosphoribosyladenosine triphosphate synthetase activity|phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase activity|adenosine triphosphate phosphoribosyltransferase activity|phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase activity|phosphoribosyladenosine triphosphate pyrophosphorylase activity|1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase activity|phosphoribosyl-ATP diphosphorylase activity|phosphoribosyl-ATP pyrophosphorylase activity|phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase activity|phosphoribosyl ATP synthetase activity											MetaCyc:ATPPHOSPHORIBOSYLTRANS-RXN|RHEA:18473|EC:2.4.2.17		molecular_function											owl:Class	
GO:0050007	biolink:NamedThing	isonocardicin synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H(+) + isonocardicin A.	got7fsn_ti	nocardicin aminocarboxypropyltransferase activity|S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase activity											MetaCyc:ISONOCARDICIN-SYNTHASE-RXN|KEGG_REACTION:R03072|EC:2.5.1.38|RHEA:19845		molecular_function											owl:Class	
GO:0018542	biolink:NamedThing	2,3-dihydroxy DDT 1,2-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0452		molecular_function											owl:Class	
GO:0090495	biolink:NamedThing	low-density lipoprotein particle disassembly	The disaggregation of a low-density lipoprotein particle into its constituent components.	got7fsn_ti							tb	2012-10-17T11:48:56Z						biological_process											owl:Class	
GO:0034518	biolink:NamedThing	RNA cap binding complex	Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA.	got7fsn_ti														cellular_component											owl:Class	
GO:0008277	biolink:NamedThing	regulation of G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.	got7fsn_ti	regulation of G-protein-coupled receptor protein signalling pathway|regulation of G protein coupled receptor protein signalling pathway|regulation of G protein coupled receptor protein signaling pathway|regulation of GPCR protein signaling pathway|regulation of GPCR protein signalling pathway|regulation of G-protein coupled receptor protein signalling pathway|regulation of G-protein coupled receptor protein signaling pathway													biological_process											owl:Class	
GO:0120084	biolink:NamedThing	endothelial tip cell filopodium assembly	The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout.	got7fsn_ti							krc	2017-07-07T18:05:10Z						biological_process											owl:Class	
GO:0046847	biolink:NamedThing	filopodium assembly	The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.	got7fsn_ti	filopodium formation|filopodia formation|filopodia biosynthesis													biological_process											owl:Class	
GO:0060773	biolink:NamedThing	flower phyllotactic patterning	The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium.	got7fsn_ti							dph	2009-07-25T06:28:38Z						biological_process											owl:Class	
GO:0030611	biolink:NamedThing	arsenate reductase activity	Catalysis of the interconversion of arsenate and arsenite.	got7fsn_ti														molecular_function											owl:Class	
GO:0039719	biolink:NamedThing	tube viral factory	A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories.	got7fsn_ti							bf	2013-12-19T15:34:56Z						cellular_component											owl:Class	
GO:0031532	biolink:NamedThing	actin cytoskeleton reorganization	A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.	got7fsn_ti	actin cytoskeleton remodeling|actin cytoskeleton reorganisation										GO:0007012			biological_process											owl:Class	
GO:1990863	biolink:NamedThing	acinar cell proliferation	The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).	got7fsn_ti	acinic cell proliferation|acinous cell proliferation						sl	2015-09-25T14:26:09Z						biological_process											owl:Class	
GO:0046575	biolink:NamedThing	rhamnogalacturonan acetylesterase activity	Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan.	got7fsn_ti														molecular_function											owl:Class	
GO:0008449	biolink:NamedThing	N-acetylglucosamine-6-sulfatase activity	Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.	got7fsn_ti	N-acetylglucosamine 6-sulfate sulfatase activity|chondroitinsulfatase|N-acetylglucosamine-6-sulphatase activity|acetylglucosamine 6-sulfatase activity|2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase activity|glucosamine-6-sulfatase activity|N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase activity|O,N-disulfate O-sulfohydrolase activity											Reactome:R-HSA-2263495|MetaCyc:3.1.6.14-RXN|EC:3.1.6.14|Reactome:R-HSA-1638032		molecular_function											owl:Class	
GO:0098617	biolink:NamedThing	adenylylselenate kinase activity	Catalysis of the reaction: ATP + adenylylselenate => ADP + 3'-phosphoadenylylselenate.	got7fsn_ti												Reactome:R-HSA-2408540		molecular_function											owl:Class	
GO:0075196	biolink:NamedThing	adhesion of symbiont haustorium mother cell to host	The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	adhesion of symbiont haustorium mother cell to host during symbiotic interaction				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0102299	biolink:NamedThing	linolenate 9R-lipoxygenase activity	Catalysis of the reaction: alpha-linolenate + O2 <=> (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate.	got7fsn_ti												RHEA:31687|EC:1.13.11.61|MetaCyc:RXN-12759		molecular_function											owl:Class	
GO:0004808	biolink:NamedThing	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate.	got7fsn_ti	tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase activity|S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase activity|transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase activity										GO:0016425	RHEA:19569|EC:2.1.1.61|MetaCyc:2.1.1.61-RXN|KEGG_REACTION:R00601		molecular_function											owl:Class	
GO:0034608	biolink:NamedThing	vulval location	Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.	got7fsn_ti														biological_process											owl:Class	
GO:0031073	biolink:NamedThing	cholesterol 26-hydroxylase activity	Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol.	got7fsn_ti														molecular_function											owl:Class	
GO:0047990	biolink:NamedThing	hydroxyglutamate decarboxylase activity	Catalysis of the reaction: 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO(2).	got7fsn_ti	3-hydroxy-L-glutamate 1-carboxy-lyase activity|3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming)											KEGG_REACTION:R04135|MetaCyc:HYDROXYGLUTAMATE-DECARBOXYLASE-RXN|RHEA:14073|EC:4.1.1.16		molecular_function											owl:Class	
GO:0045795	biolink:NamedThing	positive regulation of cell volume	Any process that increases cell volume.	got7fsn_ti														biological_process											owl:Class	
GO:0005358	biolink:NamedThing	high-affinity glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high-affinity hydrogen:glucose transporter activity|high-affinity hydrogen:glucose symporter activity|high-affinity hydrogen/glucose transporter activity													molecular_function											owl:Class	
GO:0009617	biolink:NamedThing	response to bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.	got7fsn_ti	response to bacteria										GO:0009618|GO:0009680			biological_process											owl:Class	
GO:0072168	biolink:NamedThing	specification of anterior mesonephric tubule identity	The process in which the tubules of the anterior mesonephros acquire their identity.	got7fsn_ti							mah	2010-02-26T01:52:36Z						biological_process											owl:Class	
GO:0018488	biolink:NamedThing	aryl-aldehyde oxidase activity	Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide.	got7fsn_ti	aryl-aldehyde:oxygen oxidoreductase activity											UM-BBD_reactionID:r0145|MetaCyc:ARYL-ALDEHYDE-OXIDASE-RXN|EC:1.2.3.9|RHEA:18569		molecular_function											owl:Class	
GO:0004031	biolink:NamedThing	aldehyde oxidase activity	Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.	got7fsn_ti	aldehyde:oxygen oxidoreductase activity|quinoline oxidase activity											Reactome:R-HSA-3204311|EC:1.2.3.1|MetaCyc:ALDEHYDE-OXIDASE-RXN|RHEA:16829		molecular_function											owl:Class	
GO:0010258	biolink:NamedThing	NADH dehydrogenase complex (plastoquinone) assembly	The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I.	got7fsn_ti														biological_process											owl:Class	
GO:0010257	biolink:NamedThing	NADH dehydrogenase complex assembly	The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.	got7fsn_ti														biological_process											owl:Class	
GO:0033942	biolink:NamedThing	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity	Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.	got7fsn_ti	maltooligosyl trehalose trehalohydrolase activity|4-alpha-D-{(1,4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity|malto-oligosyltrehalose trehalohydrolase activity|4-alpha-D-{(1->4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity											MetaCyc:3.2.1.141-RXN|EC:3.2.1.141		molecular_function											owl:Class	
GO:0019668	biolink:NamedThing	anaerobic catabolism of pairs of amino acids	The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.	got7fsn_ti	Stickland reaction|cofermentation of pairs of amino acids													biological_process											owl:Class	
GO:0018426	biolink:NamedThing	O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process	The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage.	got7fsn_ti	O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine anabolism|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine formation|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthesis|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine synthesis											RESID:AA0297		biological_process											owl:Class	
GO:0042757	biolink:NamedThing	giant axon	Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses.	got7fsn_ti														cellular_component											owl:Class	
GO:0047362	biolink:NamedThing	thiosulfate-dithiol sulfurtransferase activity	Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite.	got7fsn_ti	thiosulfate reductase activity|TSR|thiosulfate:dithioerythritol sulfurtransferase activity|thiosulphate-dithiol sulphurtransferase activity											RHEA:15121|MetaCyc:2.8.1.5-RXN|EC:2.8.1.5		molecular_function											owl:Class	
GO:0070877	biolink:NamedThing	microprocessor complex	A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs.	got7fsn_ti							mah	2009-08-20T03:56:26Z						cellular_component											owl:Class	
GO:1903095	biolink:NamedThing	ribonuclease III complex	A protein complex which is capable of ribonuclease III activity.	got7fsn_ti					An example of this is RNC in human (Q9NRR4) in PMID:22393237 (inferred from direct assay).		bhm	2014-06-03T15:06:39Z						cellular_component											owl:Class	
GO:0061684	biolink:NamedThing	chaperone-mediated autophagy	The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.	got7fsn_ti	CMA|chaperone-assisted selective autophagy|CASA	https://github.com/geneontology/go-ontology/issues/20850					dph	2015-03-04T14:35:26Z				Wikipedia:Chaperone-mediated_autophagy		biological_process											owl:Class	
GO:0071912	biolink:NamedThing	asynchronous neurotransmitter secretion	Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion.	got7fsn_ti							mah	2010-09-22T01:45:35Z						biological_process											owl:Class	
GO:0052813	biolink:NamedThing	phosphatidylinositol bisphosphate kinase activity	Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol trisphosphate.	got7fsn_ti							ai	2011-10-21T03:55:36Z						molecular_function											owl:Class	
GO:0032906	biolink:NamedThing	transforming growth factor beta2 production	The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	transforming growth factor-beta2 production|TGF-B2 production|TGFB2 production													biological_process											owl:Class	
GO:0052675	biolink:NamedThing	3-methylbutanol:NADP oxidoreductase activity	Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde.	got7fsn_ti	isoamyl alcohol oxidase (NADP) activity|3-methylbutanol:NADP+ oxidoreductase activity|3-methylbutyraldehyde reductase (NADP) activity|3-methylbutanal reductase (NADP) activity						ai	2011-04-12T11:19:27Z				KEGG_REACTION:R05686|RHEA:18525		molecular_function											owl:Class	
GO:0018747	biolink:NamedThing	phenanthrene-1,2-epoxide hydrolase activity	Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene.	got7fsn_ti												UM-BBD_reactionID:r0536		molecular_function											owl:Class	
GO:0019118	biolink:NamedThing	phenanthrene-epoxide hydrolase activity	Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene.	got7fsn_ti												EC:3.3.2.-		molecular_function											owl:Class	
GO:0044011	biolink:NamedThing	single-species biofilm formation on inanimate substrate	A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.	got7fsn_ti														biological_process											owl:Class	
GO:0090609	biolink:NamedThing	single-species submerged biofilm formation	A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	got7fsn_ti							tb	2014-09-16T14:55:15Z						biological_process											owl:Class	
GO:0060722	biolink:NamedThing	cell proliferation involved in embryonic placenta development	The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.	got7fsn_ti							dph	2009-06-12T12:46:04Z						biological_process											owl:Class	
GO:0033972	biolink:NamedThing	proclavaminate amidinohydrolase activity	Catalysis of the reaction: amidinoproclavaminate + H(2)O = proclavaminate + urea.	got7fsn_ti	proclavaminic acid amidino hydrolase activity|PAH|proclavaminate amidino hydrolase activity											RHEA:17001|KEGG_REACTION:R05357|EC:3.5.3.22|MetaCyc:3.5.3.22-RXN		molecular_function											owl:Class	
GO:0031767	biolink:NamedThing	gastric inhibitory polypeptide receptor binding	Binding to a gastric inhibitory polypeptide receptor.	got7fsn_ti	gastric inhibitory polypeptide receptor ligand													molecular_function											owl:Class	
GO:0008503	biolink:NamedThing	benzodiazepine receptor activity	Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity.	got7fsn_ti					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'chloride channel activity ; GO:0005254', 'GABA receptor activity ; GO:0016917' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'.									molecular_function											owl:Class	
GO:0080106	biolink:NamedThing	7-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate.	got7fsn_ti							dhl	2009-04-23T04:29:37Z						molecular_function											owl:Class	
GO:0047019	biolink:NamedThing	indole-3-acetaldehyde reductase (NADPH) activity	Catalysis of the reaction: indole-3-ethanol + NADP(+) = (indol-3-yl)acetaldehyde + H(+) + NADPH.	got7fsn_ti	indoleacetaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|indole-3-ethanol:NADP+ oxidoreductase activity|(indol-3-yl)ethanol:NADP+ oxidoreductase activity											KEGG_REACTION:R02680|MetaCyc:1.1.1.191-RXN|RHEA:17037|EC:1.1.1.191		molecular_function											owl:Class	
GO:0060992	biolink:NamedThing	response to fungicide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.	got7fsn_ti							dph	2010-01-13T08:05:58Z						biological_process											owl:Class	
GO:0045480	biolink:NamedThing	galactose oxidase activity	Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide.	got7fsn_ti	D-galactose oxidase activity|beta-galactose oxidase activity|D-galactose:oxygen 6-oxidoreductase activity											RHEA:24160|EC:1.1.3.9|MetaCyc:GALACTOSE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0102582	biolink:NamedThing	cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-15328		molecular_function											owl:Class	
GO:0050431	biolink:NamedThing	transforming growth factor beta binding	Binding to TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.	got7fsn_ti	TGF-beta binding|transforming growth factor beta ligand binding to type II receptor|TGFbeta binding|transforming growth factor beta ligand binding to type I receptor													molecular_function											owl:Class	
GO:0070224	biolink:NamedThing	sulfide:quinone oxidoreductase activity	Catalysis of the reaction: hydrogen sulfide + a quinone = S0 + a hydroquinone.	got7fsn_ti	sulfide-quinone reductase activity|sulphide:quinone oxidoreductase activity											Reactome:R-HSA-1614665|MetaCyc:R17-RXN|RHEA:30239		molecular_function											owl:Class	
GO:0016672	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound.	got7fsn_ti	oxidoreductase activity, acting on sulphur group of donors, quinone or similar compound as acceptor											EC:1.8.5.-		molecular_function											owl:Class	
GO:0046583	biolink:NamedThing	cation efflux transmembrane transporter activity	Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	cation efflux permease activity													molecular_function											owl:Class	
GO:0047459	biolink:NamedThing	3-aminobutyryl-CoA ammonia-lyase activity	Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH(4)(+).	got7fsn_ti	L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)|L-3-aminobutyryl-CoA ammonia-lyase activity|L-3-aminobutyryl-CoA deaminase activity											EC:4.3.1.14|MetaCyc:4.3.1.14-RXN|RHEA:10056|KEGG_REACTION:R03030		molecular_function											owl:Class	
GO:0036175	biolink:NamedThing	ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor	Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin.	got7fsn_ti							bf	2012-03-29T11:12:42Z				Reactome:R-HSA-111742|Reactome:R-HSA-8866405		molecular_function											owl:Class	
GO:0061731	biolink:NamedThing	ribonucleoside-diphosphate reductase activity	Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.	got7fsn_ti	ribonucleoside 5'-diphosphate reductase activity|ribonucleotide diphosphate reductase activity|aerobic non-heme iron-dependent ribonucleotide reductase activity|adenosylcobalamin-dependent ribonucleotide reductase activity|RNR|class III ribonucleotide reductase activity|class II ribonucleoside-diphosphate reductase activity|anaerobic iron-sulfur-dependent ribonucleotide reductase activity|class I ribonucleotide reductase activity|purine/pyrimidine nucleoside diphosphate reduction|nucleoside diphosphate reductase activity|ribonucleotide reductase activity|class II ribonucleotide reductase activity						dph	2015-08-24T07:25:59Z						molecular_function											owl:Class	
GO:0004984	biolink:NamedThing	olfactory receptor activity	Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell.	got7fsn_ti	odorant receptor activity													molecular_function											owl:Class	
GO:0007114	biolink:NamedThing	cell budding	A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.	got7fsn_ti	budding													biological_process											owl:Class	
GO:0089713	biolink:NamedThing	Cbf1-Met4-Met28 complex	A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation.	got7fsn_ti														cellular_component											owl:Class	
GO:0043385	biolink:NamedThing	mycotoxin metabolic process	The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.	got7fsn_ti	mycotoxin metabolism													biological_process											owl:Class	
GO:0034475	biolink:NamedThing	U4 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U4 snRNA molecule.	got7fsn_ti	U4 snRNA 3' end processing													biological_process											owl:Class	
GO:0045176	biolink:NamedThing	apical protein localization	Any process in which a protein is transported to, or maintained in, apical regions of the cell.	got7fsn_ti	establishment and maintenance of apical protein localization|establishment and maintenance of protein localization in apical part of cell|apical protein localisation													biological_process											owl:Class	
GO:0051498	biolink:NamedThing	syn-copalyl diphosphate synthase activity	Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.	got7fsn_ti	diterpene cyclase activity											EC:5.5.1.14|RHEA:25524|MetaCyc:RXN-8528		molecular_function											owl:Class	
GO:0047771	biolink:NamedThing	carboxymethylhydantoinase activity	Catalysis of the reaction: L-5-carboxymethylhydantoin + H(2)O = N-carbamoyl-L-aspartate + H(+).	got7fsn_ti	hydantoin hydrolase activity|L-5-carboxymethylhydantoin amidohydrolase activity											RHEA:12028|MetaCyc:CARBOXYMETHYLHYDANTOINASE-RXN|KEGG_REACTION:R02284|EC:3.5.2.4		molecular_function											owl:Class	
GO:0018424	biolink:NamedThing	peptidyl-glutamic acid poly-ADP-ribosylation	This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way.	got7fsn_ti												RESID:AA0295		biological_process											owl:Class	
GO:0031088	biolink:NamedThing	platelet dense granule membrane	The lipid bilayer surrounding the platelet dense granule.	got7fsn_ti														cellular_component											owl:Class	
GO:0097111	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment.	got7fsn_ti	ERGIC organization|endoplasmic reticulum-Golgi intermediate compartment organisation|ER-Golgi intermediate compartment organization|endoplasmic reticulum-Golgi intermediate compartment organization and biogenesis						pr	2011-07-29T04:45:54Z						biological_process											owl:Class	
GO:0047566	biolink:NamedThing	3-ketovalidoxylamine C-N-lyase activity	Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H(+).	got7fsn_ti	4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase [5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one-forming]|3-ketovalidoxylamine A C-N-lyase activity|4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase activity|p-nitrophenyl-3-ketovalidamine p-nitroaniline lyase activity											MetaCyc:3-KETOVALIDOXYLAMINE-C-N-LYASE-RXN|EC:4.3.3.1|KEGG_REACTION:R04367|RHEA:22768		molecular_function											owl:Class	
GO:0102800	biolink:NamedThing	caffeoyl-CoA:pelargonidin-3,5-diglucoside-6''-O-acyltransferase activity	Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A.	got7fsn_ti												MetaCyc:RXN-8138		molecular_function											owl:Class	
GO:0102970	biolink:NamedThing	7-deoxyloganetic acid glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 7-deoxyloganetate <=> H+ + 7-deoxyloganate + UDP.	got7fsn_ti												RHEA:39895|EC:2.4.1.323|MetaCyc:RXN-9372		molecular_function											owl:Class	
GO:0018522	biolink:NamedThing	benzoyl-CoA reductase activity	Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin.	got7fsn_ti	cyclohexa-1,5-diene-1-carbonyl-CoA:ferredoxin oxidoreductase (aromatizing, ATP-forming) activity|benzoyl-CoA reductase (dearomatizing) activity											UM-BBD_reactionID:r0190|RHEA:30199|MetaCyc:1.3.99.15-RXN|EC:1.3.7.8|KEGG_REACTION:R02451		molecular_function											owl:Class	
GO:0050883	biolink:NamedThing	musculoskeletal movement, spinal reflex action	Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.	got7fsn_ti														biological_process											owl:Class	
GO:0061710	biolink:NamedThing	L-threonylcarbamoyladenylate synthase	Catalysis of the reaction:  L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O.	got7fsn_ti							dph	2015-06-23T08:25:14Z				MetaCyc:RXN-14569|RHEA:36407|EC:2.7.7.87		molecular_function											owl:Class	
GO:0006501	biolink:NamedThing	C-terminal protein lipidation	The covalent attachment of a lipid group to the carboxy-terminus of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0106028	biolink:NamedThing	neuron projection retraction	The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	got7fsn_ti	neuron projection disassembly						hjd	2017-06-23T18:32:42Z						biological_process											owl:Class	
GO:0106027	biolink:NamedThing	neuron projection organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite.	got7fsn_ti							hjd	2017-06-23T18:30:18Z						biological_process											owl:Class	
GO:0004566	biolink:NamedThing	beta-glucuronidase activity	Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.	got7fsn_ti	exo-beta-D-glucuronidase activity|glucuronidase activity|beta-D-glucuronoside glucuronosohydrolase activity|beta-glucuronide glucuronohydrolase activity|ketodase activity											Reactome:R-HSA-2162226|Reactome:R-HSA-9036070|Reactome:R-HSA-2318373|MetaCyc:BETA-GLUCURONID-RXN|Reactome:R-HSA-2162227|RHEA:17633|Reactome:R-HSA-1678854|Reactome:R-HSA-9036068|EC:3.2.1.31		molecular_function											owl:Class	
GO:0060325	biolink:NamedThing	face morphogenesis	The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.	got7fsn_ti														biological_process											owl:Class	
GO:0102512	biolink:NamedThing	delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + vanillate + H+.	got7fsn_ti												EC:2.4.1.299|MetaCyc:RXN-14441		molecular_function											owl:Class	
GO:0005612	biolink:NamedThing	laminin-7 complex	A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.	got7fsn_ti	laminin-321 complex|laminin-7A													cellular_component											owl:Class	
GO:0046099	biolink:NamedThing	guanine biosynthetic process	The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.	got7fsn_ti	guanine formation|guanine biosynthesis|guanine anabolism|guanine synthesis													biological_process											owl:Class	
GO:0036307	biolink:NamedThing	23S rRNA (adenine(2030)-N(6))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA.	got7fsn_ti							bf	2012-08-08T14:15:48Z						molecular_function											owl:Class	
GO:0047040	biolink:NamedThing	pteridine reductase activity	Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 H(+) + 2 NADPH.	got7fsn_ti	ptr1 activity|pteridine reductase 1 activity|PTR1|5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase activity|dihydrobiopterin reduction				Note that this function was formerly EC:1.1.1.253.							MetaCyc:1.1.1.253-RXN|EC:1.5.1.33|RHEA:19509|KEGG_REACTION:R01812		molecular_function											owl:Class	
GO:0102166	biolink:NamedThing	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-threonine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-threonine.	got7fsn_ti												RHEA:48892|EC:3.2.1.169|MetaCyc:RXN-11891		molecular_function											owl:Class	
GO:0097621	biolink:NamedThing	monoamine oxidase activity	Catalysis of the reaction: RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.	got7fsn_ti	amine:oxygen oxidoreductase (deaminating) activity				Acts on primary amines, and also on some secondary and tertiary amines. It differs from EC:1.4.3.21, primary-amine oxidase as it can oxidize secondary and tertiary amines but not methylamine.		pr	2014-07-30T10:23:57Z				RHEA:26414		molecular_function											owl:Class	
GO:0005715	biolink:NamedThing	late recombination nodule	An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I.	got7fsn_ti														cellular_component											owl:Class	
GO:0005713	biolink:NamedThing	recombination nodule	An electron dense structure that is associated with meiotic chromosomes.	got7fsn_ti														cellular_component											owl:Class	
GO:0033824	biolink:NamedThing	alternansucrase activity	Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages.	got7fsn_ti	sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase activity|sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase activity|sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase activity											EC:2.4.1.140|MetaCyc:2.4.1.140-RXN		molecular_function											owl:Class	
GO:0018284	biolink:NamedThing	iron incorporation into protein via tetrakis-L-cysteinyl iron	The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein).	got7fsn_ti												RESID:AA0136		biological_process											owl:Class	
GO:0018742	biolink:NamedThing	epoxide hydrolase B activity	Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers.	got7fsn_ti												EC:3.3.2.-|UM-BBD_enzymeID:e0051		molecular_function											owl:Class	
GO:0035541	biolink:NamedThing	negative regulation of SNARE complex disassembly	Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	got7fsn_ti							bf	2010-05-10T01:42:47Z						biological_process											owl:Class	
GO:0007540	biolink:NamedThing	sex determination, establishment of X:A ratio	The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it.	got7fsn_ti														biological_process											owl:Class	
GO:0102175	biolink:NamedThing	3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity	Catalysis of the reaction: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH.	got7fsn_ti												MetaCyc:RXN-11928|RHEA:34775		molecular_function											owl:Class	
GO:0032588	biolink:NamedThing	trans-Golgi network membrane	The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.	got7fsn_ti	Golgi trans face membrane|trans Golgi network membrane													cellular_component											owl:Class	
GO:0042287	biolink:NamedThing	MHC protein binding	Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.	got7fsn_ti	major histocompatibility complex ligand|major histocompatibility complex binding				Note that this term does not include binding to the antigen peptide bound to the MHC protein, for this also annotate to 'peptide antigen binding ; GO:0042605' or one of its children.									molecular_function											owl:Class	
GO:2000934	biolink:NamedThing	negative regulation of cellotriose metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process.	got7fsn_ti	negative regulation of cellotriose metabolism						tt	2011-08-01T12:44:20Z						biological_process											owl:Class	
GO:0080006	biolink:NamedThing	internode patterning	Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.	got7fsn_ti														biological_process											owl:Class	
GO:0002085	biolink:NamedThing	inhibition of neuroepithelial cell differentiation	Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.	got7fsn_ti	negative regulation of neural plate formation|repression of premature neural plate formation													biological_process											owl:Class	
GO:0110008	biolink:NamedThing	ncRNA deadenylation	Shortening of the poly(A) tail of a nuclear-transcribed ncRNA.	got7fsn_ti							kmv							biological_process											owl:Class	
GO:0060543	biolink:NamedThing	negative regulation of strand invasion	Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.	got7fsn_ti	negative regulation of D-loop biosynthesis|negative regulation of D-loop formation|negative regulation of Rad51-mediated strand invasion						dph	2009-04-13T01:32:36Z						biological_process											owl:Class	
GO:0047006	biolink:NamedThing	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity	Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.	got7fsn_ti	20alpha-hydroxy steroid dehydrogenase activity|20alpha-HSDH|20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity|20alpha-hydroxysteroid dehydrogenase|20alpha-HSD											MetaCyc:1.1.1.149-RXN|EC:1.1.1.149		molecular_function											owl:Class	
GO:0015068	biolink:NamedThing	glycine amidinotransferase activity	Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.	got7fsn_ti	L-arginine:glycine amidinotransferase activity|arginine-glycine amidinotransferase activity|arginine-glycine transamidinase activity|glycine transamidinase activity											RHEA:13201|Reactome:R-HSA-71275|EC:2.1.4.1|MetaCyc:GLYCINE-AMIDINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0072243	biolink:NamedThing	metanephric nephron epithelium development	The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.	got7fsn_ti							mah	2010-03-19T03:29:49Z						biological_process											owl:Class	
GO:0019712	biolink:NamedThing	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamic acid	The methyl esterification of peptidyl-glutamic acid.	got7fsn_ti	peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamic acid|peptidyl-L-glutamic acid 5-methyl ester formation from glutamic acid|peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamic acid											RESID:AA0072		biological_process											owl:Class	
GO:0070179	biolink:NamedThing	D-serine biosynthetic process	The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine.	got7fsn_ti	D-serine anabolism|D-serine formation|D-serine biosynthesis|D-serine synthesis													biological_process											owl:Class	
GO:0010961	biolink:NamedThing	cellular magnesium ion homeostasis	Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell.	got7fsn_ti							tb	2009-05-06T11:48:45Z						biological_process											owl:Class	
GO:0102520	biolink:NamedThing	L-threonine O-3-phosphate phosphatase activity	Catalysis of the reaction: O-phospho-L-threonine + H2O = L-threonine  + hydrogenphosphate.	got7fsn_ti												MetaCyc:RXN-14505		molecular_function											owl:Class	
GO:0005940	biolink:NamedThing	septin ring	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.	got7fsn_ti											GO:0030481	Wikipedia:Septin_ring		cellular_component											owl:Class	
GO:0044582	biolink:NamedThing	butyryl-CoA catabolic process to butanol	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol.	got7fsn_ti	butyryl-CoA catabolism to butanol						jl	2012-04-19T04:40:06Z						biological_process											owl:Class	
GO:0071271	biolink:NamedThing	1-butanol biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O.	got7fsn_ti	butanol biosynthetic process|1-butanol biosynthesis|1-butanol formation|butan-1-ol biosynthetic process|1-butanol anabolism|1-butanol synthesis						mah	2009-12-10T10:27:24Z						biological_process											owl:Class	
GO:0047924	biolink:NamedThing	geraniol dehydrogenase activity	Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH.	got7fsn_ti	geraniol:NADP+ oxidoreductase activity											MetaCyc:GERANIOL-DEHYDROGENASE-RXN|UM-BBD_reactionID:r1163|EC:1.1.1.183|RHEA:14521		molecular_function											owl:Class	
GO:0120031	biolink:NamedThing	plasma membrane bounded cell projection assembly	Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.	got7fsn_ti	eupodium	https://github.com/geneontology/go-ontology/issues/13298					krc	2017-04-24T23:56:08Z						biological_process											owl:Class	
GO:0080118	biolink:NamedThing	brassinosteroid sulfotransferase activity	Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative.	got7fsn_ti							dhl	2009-04-27T03:39:36Z						molecular_function											owl:Class	
GO:0031874	biolink:NamedThing	type 3 proteinase activated receptor binding	Binding to a type 3 proteinase activated receptor.	got7fsn_ti	type 3 proteinase activated receptor ligand													molecular_function											owl:Class	
GO:0048383	biolink:NamedThing	mesectoderm development	The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0016996	biolink:NamedThing	endo-alpha-(2,8)-sialidase activity	Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.	got7fsn_ti	endo-N-acylneuraminidase activity|endoneuraminidase activity|polysialoside (2->8)-alpha-sialosylhydrolase activity|alpha-2,8-sialosylhydrolase activity|poly(alpha-2,8-sialoside) alpha-2,8-sialosylhydrolase activity|poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase activity|endosialidase activity|endo-N-acetylneuraminidase activity											EC:3.2.1.129|MetaCyc:3.2.1.129-RXN		molecular_function											owl:Class	
GO:0042044	biolink:NamedThing	fluid transport	The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0050624	biolink:NamedThing	vomilenine reductase activity	Catalysis of the reaction: 1,2-dihydrovomilenine + NADP(+) = H(+) + NADPH + vomilenine.	got7fsn_ti	1,2-dihydrovomilenine:NADP+ oxidoreductase activity											MetaCyc:1.5.1.32-RXN|KEGG_REACTION:R05878|RHEA:16409|EC:1.5.1.32		molecular_function											owl:Class	
GO:0032611	biolink:NamedThing	interleukin-1 beta production	The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-1 beta secretion|interleukin-1 beta biosynthetic process|IL-1 beta production										GO:0050702|GO:0050720			biological_process											owl:Class	
GO:0032612	biolink:NamedThing	interleukin-1 production	The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-1 production|interleukin-1 biosynthetic process|interleukin-1 secretion										GO:0042222|GO:0050701			biological_process											owl:Class	
GO:0004088	biolink:NamedThing	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.	got7fsn_ti	carbamoylphosphate synthetase II activity|carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity|carbamoyl phosphate synthase (glutamine-hydrolyzing) activity|GD-CPSase activity|carbamoyl phosphate synthetase activity|carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity|glutamine-dependent carbamyl phosphate synthetase activity|carbamyl phosphate synthetase (glutamine) activity|carbamoyl-phosphate synthase (glutamine-hydrolysing) activity|hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity|CPS activity|glutamine-dependent carbamoyl-phosphate synthase activity|carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity											Reactome:R-HSA-73577|RHEA:18633|MetaCyc:CARBPSYN-RXN|EC:6.3.5.5		molecular_function											owl:Class	
GO:0140483	biolink:NamedThing	kinetochore adaptor activity	The binding activity of a protein that brings the kinetochore and another molecule into contact, permitting those molecules to function in a coordinated way.	got7fsn_ti	inner kinetochore adaptor activity|outer kinetochore adaptor activity	https://github.com/geneontology/go-ontology/issues/19701|https://github.com/geneontology/go-ontology/issues/21091					pg	2020-06-29T08:53:10Z						molecular_function											owl:Class	
GO:0046975	biolink:NamedThing	histone methyltransferase activity (H3-K36 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein.	got7fsn_ti	histone lysine N-methyltransferase activity (H3-K36 specific)|histone methylase activity (H3-K36 specific)													molecular_function											owl:Class	
GO:0050587	biolink:NamedThing	chlorite O2-lyase activity	Catalysis of the reaction: chloride + O(2) = chlorite.	got7fsn_ti	chlorite dismutase activity|chloride:oxygen oxidoreductase activity										GO:0030065	MetaCyc:1.13.11.49-RXN|KEGG_REACTION:R05721|UM-BBD_reactionID:r0982|RHEA:21404|EC:1.13.11.49		molecular_function											owl:Class	
GO:0018378	biolink:NamedThing	cytochrome c-heme linkage via heme-L-cysteine	The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine.	got7fsn_ti	cytochrome c-haem linkage via haem-L-cysteine											RESID:AA0135		biological_process											owl:Class	
GO:0102117	biolink:NamedThing	gibberellin A9 carboxyl methyltransferase activity	Catalysis of the reaction: gibberellin A9 + S-adenosyl-L-methionine  <=> gibberellin A9 methyl ester + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-11358|EC:2.1.1.275|RHEA:36119		molecular_function											owl:Class	
GO:0060452	biolink:NamedThing	positive regulation of cardiac muscle contraction	Any process that increases the frequency, rate or extent of cardiac muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0045989	biolink:NamedThing	positive regulation of striated muscle contraction	Any process that activates or increases the frequency, rate or extent of striated muscle contraction.	got7fsn_ti	activation of striated muscle contraction|up-regulation of striated muscle contraction|upregulation of striated muscle contraction|up regulation of striated muscle contraction|stimulation of striated muscle contraction													biological_process											owl:Class	
GO:0042161	biolink:NamedThing	lipoprotein oxidation	The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group.	got7fsn_ti														biological_process											owl:Class	
GO:0047757	biolink:NamedThing	chondroitin-glucuronate 5-epimerase activity	Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate.	got7fsn_ti	chondroitin D-glucuronosyl 5-epimerase activity|dermatan-sulfate 5-epimerase activity|polyglucuronate 5-epimerase activity|urunosyl C-5 epimerase activity|chondroitin-D-glucuronate 5-epimerase activity											RHEA:21084|Reactome:R-HSA-2022052|MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN|EC:5.1.3.19		molecular_function											owl:Class	
GO:0005631	biolink:NamedThing	chitosan layer of spore wall	The second outermost layer of the spore wall, as described in Saccharomyces.	got7fsn_ti														cellular_component											owl:Class	
GO:0052629	biolink:NamedThing	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+.	got7fsn_ti												Reactome:R-HSA-1676105|EC:3.1.3.95|Reactome:R-HSA-6809778|MetaCyc:RXN-10958|RHEA:39019|Reactome:R-HSA-1676203|Reactome:R-HSA-1676065|Reactome:R-HSA-6809320|Reactome:R-HSA-6809944		molecular_function											owl:Class	
GO:0097368	biolink:NamedThing	establishment of Sertoli cell barrier	Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.	got7fsn_ti	establishment of BTB|establishment of blood-testis barrier|establishment of SCB						pr	2012-08-02T17:05:55Z						biological_process											owl:Class	
GO:0047641	biolink:NamedThing	aldose-6-phosphate reductase (NADPH) activity	Catalysis of the reaction: D-glucitol 6-phosphate + NADP(+) = D-glucose 6-phosphate + H(+) + NADPH.	got7fsn_ti	NADP-dependent aldose 6-phosphate reductase activity|NADP-dependent D-sorbitol-6-phosphate dehydrogenase activity|alditol 6-phosphate:NADP 1-oxidoreductase activity|A6PR|aldose-6-phosphate reductase activity|aldose-6-P reductase activity|aldose 6-phosphate reductase activity|D-aldose-6-phosphate:NADP+ 1-oxidoreductase activity											EC:1.1.1.200|KEGG_REACTION:R00834|RHEA:20037|MetaCyc:ALDOSE-6-PHOSPHATE-REDUCTASE-NADPH-RXN		molecular_function											owl:Class	
GO:0075031	biolink:NamedThing	positive regulation of formation of symbiont germ tube hook structure for appressorium development	Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation.	got7fsn_ti	positive regulation of formation of symbiont germ tube hook structure on or near host|positive regulation of symbiont germ tube hook structure formation on or near host|positive regulation of germ tube tip of symbiont on or near the exterior of host													biological_process											owl:Class	
GO:0075027	biolink:NamedThing	positive regulation of appressorium initiation	Any process that activates or increases the frequency, rate or extent of symbiont appressorium initiation.	got7fsn_ti	positive regulation of initiation of appressorium on or near host|positive regulation of appressorium initiation on or near host													biological_process											owl:Class	
GO:0006796	biolink:NamedThing	phosphate-containing compound metabolic process	The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.	got7fsn_ti	phosphate metabolism|phosphate metabolic process													biological_process											owl:Class	
GO:0097635	biolink:NamedThing	extrinsic component of autophagosome membrane	The component of the autophagosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to autophagic vacuole membrane|autophagic vacuole peripheral membrane|extrinsic component of autophagic vacuole membrane													cellular_component											owl:Class	
GO:0005053	biolink:NamedThing	peroxisome matrix targeting signal-2 binding	Binding to a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F).	got7fsn_ti	PTS2 binding|peroxisome targeting signal-2 binding|peroxisomal targeting signal 2 (PTS2) binding|peroxisome targeting signal-2 receptor|PTS2 receptor|PEX7													molecular_function											owl:Class	
GO:0000268	biolink:NamedThing	peroxisome targeting sequence binding	Binding to a peroxisomal targeting sequence, a sequence of amino acids within a protein that acts as a signal for the localization of a protein into the peroxisome.	got7fsn_ti	PTS receptor|PTS binding|peroxisome targeting signal receptor										GO:0005051			molecular_function											owl:Class	
GO:0044864	biolink:NamedThing	positive regulation by virus of host cell division	Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division.	got7fsn_ti							jl	2014-08-05T16:31:20Z						biological_process											owl:Class	
GO:0051781	biolink:NamedThing	positive regulation of cell division	Any process that activates or increases the frequency, rate or extent of cell division.	got7fsn_ti	upregulation of cell division|activation of cell division|up-regulation of cell division|up regulation of cell division|stimulation of cell division													biological_process											owl:Class	
GO:0022032	biolink:NamedThing	telencephalon oligodendrocyte cell migration	The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0050866	biolink:NamedThing	negative regulation of cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.	got7fsn_ti	down regulation of cell activation|downregulation of cell activation|down-regulation of cell activation|inhibition of cell activation													biological_process											owl:Class	
GO:0050698	biolink:NamedThing	proteoglycan sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.	got7fsn_ti	proteoglycan sulphotransferase activity|proteoglycan sulfate transfer													molecular_function											owl:Class	
GO:0005790	biolink:NamedThing	smooth endoplasmic reticulum	The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.	got7fsn_ti	smooth ER|SER											Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum|NIF_Subcellular:sao710427438		cellular_component											owl:Class	
GO:0102341	biolink:NamedThing	3-oxo-lignoceroyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP <=> 3-oxotetracosanoyl-CoA + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13300|EC:1.1.1.330		molecular_function											owl:Class	
GO:0001857	biolink:NamedThing	complement component C1q receptor activity	Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0001544	biolink:NamedThing	initiation of primordial ovarian follicle growth	Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle).	got7fsn_ti														biological_process											owl:Class	
GO:0015181	biolink:NamedThing	arginine transmembrane transporter activity	Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.	got7fsn_ti	histidine/arginine/lysine/ornithine porter activity|L-arginine transporter activity|arginine permease activity										GO:0005288	RHEA:32143		molecular_function											owl:Class	
GO:0007362	biolink:NamedThing	terminal region determination	Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.	got7fsn_ti														biological_process											owl:Class	
GO:0060273	biolink:NamedThing	crying behavior	The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.	got7fsn_ti														biological_process											owl:Class	
GO:0004095	biolink:NamedThing	carnitine O-palmitoyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.	got7fsn_ti	carnitine palmitoyltransferase I|outer malonyl-CoA inhibitable carnitine palmitoyltransferase activity|carnitine palmitoyltransferase-A|palmitoyl-CoA:L-carnitine O-palmitoyltransferase activity|CPT-B|acylcarnitine transferase activity|carnitine palmitoyltransferase activity|CPT I (outer membrane carnitine palmitoyl transferase)|L-carnitine palmitoyltransferase activity|CPTo|CPT-A|CPT|carnitine palmitoyltransferase II|palmitoylcarnitine transferase activity|CPTi											MetaCyc:CARNITINE-O-PALMITOYLTRANSFERASE-RXN|Reactome:R-HSA-200410|RHEA:12661|Reactome:R-HSA-200406|EC:2.3.1.21		molecular_function											owl:Class	
GO:0019142	biolink:NamedThing	2-hydroxyglutarate synthase activity	Catalysis of the reaction: glyoxylate + H(2)O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+).	got7fsn_ti	propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)|2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity|hydroxyglutarate synthase activity|alpha-hydroxyglutarate synthase activity|2-hydroxyglutaric synthetase activity|2-hydroxyglutaratic synthetase activity				Note that this function was formerly EC:4.1.3.9.							KEGG_REACTION:R00932|RHEA:19185|EC:2.3.3.11|MetaCyc:HYDGLUTSYN-RXN		molecular_function											owl:Class	
GO:0021979	biolink:NamedThing	hypothalamus cell differentiation	The differentiation of cells that will contribute to the structure and function of the hypothalamus.	got7fsn_ti														biological_process											owl:Class	
GO:0047742	biolink:NamedThing	chenodeoxycholoyltaurine hydrolase activity	Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine.	got7fsn_ti	chenodeoxycholoyltaurine amidohydrolase activity											MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN|EC:3.5.1.74|RHEA:16309		molecular_function											owl:Class	
GO:0038018	biolink:NamedThing	Wnt receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.	got7fsn_ti	Wnt receptor catabolism|Wnt receptor degradation|Wnt receptor breakdown|Frizzled degradation|negative regulation of Wnt receptor signaling pathway by Wnt receptor degradation						bf	2011-06-23T04:38:12Z						biological_process											owl:Class	
GO:0055060	biolink:NamedThing	asymmetric neuroblast division resulting in ganglion mother cell formation	Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell.	got7fsn_ti														biological_process											owl:Class	
GO:0014017	biolink:NamedThing	neuroblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.	got7fsn_ti														biological_process											owl:Class	
GO:0004013	biolink:NamedThing	adenosylhomocysteinase activity	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.	got7fsn_ti	S-adenosyl-L-homocysteine hydrolase activity|S-adenosylhomocysteine hydrolase activity|S-adenosylhomocysteine synthase activity|S-adenosylhomocysteinase activity|AdoHcyase activity|adenosylhomocysteine hydrolase activity|SAHase activity											Reactome:R-HSA-5579084|RHEA:21708|MetaCyc:ADENOSYLHOMOCYSTEINASE-RXN|Reactome:R-HSA-174401|EC:3.3.1.1		molecular_function											owl:Class	
GO:0005020	biolink:NamedThing	stem cell factor receptor activity	Combining with stem cell factor (SCF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation.	got7fsn_ti	SCF receptor activity|KIT ligand receptor activity|KIT|KL receptor activity													molecular_function											owl:Class	
GO:0050697	biolink:NamedThing	1,1,2-trichloroethene reductive dehalogenase activity	Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene.	got7fsn_ti	TCE-reductive dehalogenase activity|1,1,2-trichloroethylene reductive dehalogenase activity											MetaCyc:TCEREDCHLOR-RXN|UM-BBD_enzymeID:e0271		molecular_function											owl:Class	
GO:0030783	biolink:NamedThing	[cytochrome c]-methionine S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine.	got7fsn_ti	cytochrome c-methionine S-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-methionine S-methyltransferase activity											MetaCyc:2.1.1.123-RXN|EC:2.1.1.123		molecular_function											owl:Class	
GO:0047487	biolink:NamedThing	oligogalacturonide lyase activity	Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate.	got7fsn_ti	OGTE|oligogalacturonate lyase activity|unsaturated oligogalacturonate transeliminase activity											MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN|EC:4.2.2.6|RHEA:20269		molecular_function											owl:Class	
GO:0102755	biolink:NamedThing	gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity	Catalysis of the reaction: gibberellin A15 (closed lactone form) + O2 + 2-oxoglutarate = gibberellin A37 (closed lactone form) + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-7680		molecular_function											owl:Class	
GO:0019424	biolink:NamedThing	sulfide oxidation, using siroheme sulfite reductase	A sulfide oxidation process that proceeds via the reaction catalyzed by siroheme sulfite reductase.	got7fsn_ti	sulphur oxidation, using siroheme sulphite reductase|sulphide oxidation, using siroheme sulphite reductase|sulfur oxidation, using sirohaem sulfite reductase|sulfide oxidation, using sirohaem sulfite reductase|sulfur oxidation, using siroheme sulfite reductase										GO:0019425	MetaCyc:P223-PWY		biological_process											owl:Class	
GO:0120022	biolink:NamedThing	glucagon family peptide binding	Binding to a member of the glucagon family peptide hormone (e.g. glucagon, glucagon-like peptides, oxyntomodulin, glicentin, ADCYAP1, GHRH, secretin, VIP, GIP).	got7fsn_ti	glucagon binding|glucagon-like peptide binding	https://github.com/geneontology/go-ontology/issues/13143|https://github.com/geneontology/go-ontology/issues/21327					krc	2017-03-17T14:46:29Z			GO:0120024			molecular_function											owl:Class	
GO:0072116	biolink:NamedThing	pronephros formation	The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	got7fsn_ti	pronephric kidney formation						mah	2010-02-22T11:16:26Z						biological_process											owl:Class	
GO:0072003	biolink:NamedThing	kidney rudiment formation	The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti	kidney anlage formation						mah	2010-01-25T11:18:58Z						biological_process											owl:Class	
GO:0046175	biolink:NamedThing	aldonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.	got7fsn_ti	aldonic acid biosynthesis|aldonic acid synthesis|aldonic acid formation|aldonic acid anabolism													biological_process											owl:Class	
GO:0035473	biolink:NamedThing	lipase binding	Binding to a lipase.	got7fsn_ti							bf	2010-04-22T05:28:52Z						molecular_function											owl:Class	
GO:0006236	biolink:NamedThing	cytidine salvage	Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0003011	biolink:NamedThing	involuntary skeletal muscle contraction	A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.	got7fsn_ti														biological_process											owl:Class	
GO:0097653	biolink:NamedThing	unencapsulated part of cell	The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures.	got7fsn_ti	non-encapsulated part of cell						pr	2014-09-23T12:57:14Z						cellular_component											owl:Class	
GO:0004598	biolink:NamedThing	peptidylamidoglycolate lyase activity	Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate.	got7fsn_ti	HGAD|alpha-hydroxyglycine amidating dealkylase activity|PGL|PAL|peptidylamidoglycolate peptidylamide-lyase activity|peptidylamidoglycolate peptidylamide-lyase (glyoxylate-forming)|peptidyl-alpha-hydroxyglycine alpha-amidating lyase activity											MetaCyc:PEPTIDYLAMIDOGLYCOLATE-LYASE-RXN|EC:4.3.2.5|RHEA:20924		molecular_function											owl:Class	
GO:0098502	biolink:NamedThing	DNA dephosphorylation	The process of removing one or more phosphate groups from a DNA molecule.	got7fsn_ti							dos	2013-09-18T14:50:16Z						biological_process											owl:Class	
GO:0010415	biolink:NamedThing	unsubstituted mannan metabolic process	The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units.	got7fsn_ti	unsubstituted mannan metabolism													biological_process											owl:Class	
GO:0046983	biolink:NamedThing	protein dimerization activity	The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.	got7fsn_ti														molecular_function											owl:Class	
GO:0018743	biolink:NamedThing	phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene.	got7fsn_ti												UM-BBD_reactionID:r0560|EC:3.3.2.-		molecular_function											owl:Class	
GO:0019119	biolink:NamedThing	phenanthrene-9,10-epoxide hydrolase activity	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene.	got7fsn_ti														molecular_function											owl:Class	
GO:0047080	biolink:NamedThing	deoxyuridine 2'-dioxygenase activity	Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = CO(2) + succinate + uridine.	got7fsn_ti	thymidine 2-oxoglutarate dioxygenase activity|pyrimidine deoxyribonucleoside 2'-hydroxylase activity|pyrimidine-deoxynucleoside 2'-dioxygenase activity|thymidine 2'-dioxygenase activity|deoxyuridine 2'-hydroxylase activity|2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating)|pyrimidine-deoxynucleoside,2-oxoglutarate 2'-dioxygenase activity|thymidine dioxygenase activity|thymidine 2'-hydroxylase activity											MetaCyc:1.14.11.3-RXN|RHEA:21076|EC:1.14.11.3|KEGG_REACTION:R01879		molecular_function											owl:Class	
GO:0043878	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+.	got7fsn_ti	NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde-3-phosphate dehydrogenase (NAD) (non-phosphorylating) activity|glyceraldehyde-3-phosphate dehydrogenase (NAD) activity|non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD)											EC:1.2.1.3|MetaCyc:RXN-3443|RHEA:25294		molecular_function											owl:Class	
GO:0001735	biolink:NamedThing	prenylcysteine oxidase activity	Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.	got7fsn_ti	prenylcysteine lyase activity|S-prenyl-L-cysteine:oxygen oxidoreductase activity											RHEA:53892|EC:1.8.3.5|MetaCyc:1.8.3.5-RXN		molecular_function											owl:Class	
GO:0006756	biolink:NamedThing	AMP phosphorylation	The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP.	got7fsn_ti														biological_process											owl:Class	
GO:0047601	biolink:NamedThing	acetate kinase (diphosphate) activity	Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate.	got7fsn_ti	pyrophosphate-acetate phosphotransferase activity|diphosphate:acetate phosphotransferase activity|acetate kinase (pyrophosphate) activity											RHEA:24276|EC:2.7.2.12|KEGG_REACTION:R00320|MetaCyc:ACETATE-KINASE-PYROPHOSPHATE-RXN		molecular_function											owl:Class	
GO:0004436	biolink:NamedThing	phosphatidylinositol diacylglycerol-lyase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol.	got7fsn_ti	monophosphatidylinositol phosphodiesterase activity|1-phosphatidylinositol phosphodiesterase activity|1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming)|1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming)|1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase (1D-myo-inositol-1,2-cyclic-phosphate-forming)				Note that this function was formerly EC:3.1.4.10.							MetaCyc:3.1.4.10-RXN|RHEA:17093|EC:4.6.1.13		molecular_function											owl:Class	
GO:0102165	biolink:NamedThing	(Z)-3-hexen-1-ol acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + (Z)-hex-3-en-1-ol <=> (3Z)-hex-3-en-1-yl acetate + coenzyme A.	got7fsn_ti												MetaCyc:RXN-11852|EC:2.3.1.195|RHEA:28254		molecular_function											owl:Class	
GO:0002368	biolink:NamedThing	B cell cytokine production	Any process that contributes to cytokine production by a B cell.	got7fsn_ti	B lymphocyte cytokine production|B-lymphocyte cytokine production|B-cell cytokine production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0006705	biolink:NamedThing	mineralocorticoid biosynthetic process	The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.	got7fsn_ti	mineralocorticoid formation|mineralocorticoid synthesis|mineralocorticoid biosynthesis|mineralocorticoid anabolism													biological_process											owl:Class	
GO:0050562	biolink:NamedThing	lysine-tRNA(Pyl) ligase activity	Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP.	got7fsn_ti	lysine-tRNAPyl ligase activity|L-lysine:tRNAPyl ligase (AMP-forming)											MetaCyc:6.1.1.25-RXN		molecular_function											owl:Class	
GO:1990377	biolink:NamedThing	organomineral extracellular matrix	An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight.	got7fsn_ti					An example is found in shell calcitic prisms of the Mediterranean fan mussel Pinna nobilis (PMID:15994301), but the term may also be useful to annotate bone and eggshell proteins.		pr	2014-05-07T10:02:28Z						cellular_component											owl:Class	
GO:0043972	biolink:NamedThing	histone H3-K23 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone.	got7fsn_ti	histone H3K23 acetylation|histone H3 acetylation at K23													biological_process											owl:Class	
GO:0007569	biolink:NamedThing	cell aging	An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).	got7fsn_ti	cell ageing													biological_process											owl:Class	
GO:0048538	biolink:NamedThing	thymus development	The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.	got7fsn_ti					Note that this term is reserved for annotation of gene products involved in the formation of the thymus itself, not for gene products involved in T cell differentiation in the thymus or elsewhere.									biological_process											owl:Class	
GO:0061708	biolink:NamedThing	tRNA-5-taurinomethyluridine 2-sulfurtransferase	Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.	got7fsn_ti							dph	2015-06-16T09:02:23Z				Reactome:R-HSA-6787447|RHEA:47040|MetaCyc:RXN-16821		molecular_function											owl:Class	
GO:0009799	biolink:NamedThing	specification of symmetry	The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created.	got7fsn_ti	determination of symmetry													biological_process											owl:Class	
GO:0039554	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	got7fsn_ti	suppression by virus of host IFIH1 signaling pathway|Inhibition of host MDA5 by virus|suppression by virus of host MDA-5 activity|inhibition by virus of host MDA-5 signaling|inhibition of host IFIH1/MDA5 by virus|suppression by virus of host MDA-5 signaling pathway|suppression by virus of host MDA-5 signalling pathway	https://github.com/geneontology/go-ontology/issues/21984					bf	2012-03-09T03:03:49Z			GO:0039539			biological_process											owl:Class	
GO:0018670	biolink:NamedThing	4-aminobenzoate 1-monooxygenase activity	Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2.	got7fsn_ti	4-aminobenzoate hydroxylase activity|4-aminobenzoate dehydrogenase activity|4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)|4-aminobenzoate monooxygenase activity											EC:1.14.13.27|MetaCyc:4-AMINOBENZOATE-1-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0597		molecular_function											owl:Class	
GO:1990344	biolink:NamedThing	secondary cell septum biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division.	got7fsn_ti							mah	2014-03-24T13:24:48Z						biological_process											owl:Class	
GO:0017116	biolink:NamedThing	single-stranded DNA helicase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.	got7fsn_ti	ssDNA-dependent ATP-dependent DNA helicase activity|single-stranded DNA-dependent ATPase activity|single-stranded DNA-dependent ATP-dependent DNA helicase activity|ssDNA-dependent ATPase activity										GO:0043142			molecular_function											owl:Class	
GO:0097121	biolink:NamedThing	cyclin A1-CDK1 complex	A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:41:25Z						cellular_component											owl:Class	
GO:0019116	biolink:NamedThing	hydroxy-nicotine oxidase activity	Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide.	got7fsn_ti												EC:1.5.3.6		molecular_function											owl:Class	
GO:0050664	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule.	got7fsn_ti	oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor											EC:1.6.3.-		molecular_function											owl:Class	
GO:0030487	biolink:NamedThing	inositol-4,5-bisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0050555	biolink:NamedThing	2-hydroxypropyl-CoM lyase activity	Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane.	got7fsn_ti	epoxypropyl:CoM transferase activity|epoxyalkane:2-mercaptoethanesulfonate transferase activity|(R)-2-hydroxypropyl-CoM 2-mercaptoethanesulfonate lyase (cyclizing; epoxyalkane-ring-forming)|epoxypropane:coenzyme M transferase activity|(R)-[or (S)-]2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)|2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)|coenzyme M-epoxyalkane ligase activity|epoxyalkane:CoM transferase activity|EaCoMT activity|epoxyalkane:coenzyme M transferase activity|epoxyalkyl:CoM transferase activity											MetaCyc:4.2.99.19-RXN|EC:4.4.1.23|RHEA:19421|UM-BBD_enzymeID:e0538		molecular_function											owl:Class	
GO:0062140	biolink:NamedThing	hyphae septin collar	A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell.	got7fsn_ti	septin collar of invasive hyphae	https://github.com/geneontology/go-ontology/issues/19013					dph	2019-08-06T14:31:04Z						cellular_component											owl:Class	
GO:0032173	biolink:NamedThing	septin collar	A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell.	got7fsn_ti	septin hourglass	https://github.com/geneontology/go-ontology/issues/19534												cellular_component											owl:Class	
GO:0102007	biolink:NamedThing	acyl-L-homoserine-lactone lactonohydrolase activity	Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine.	got7fsn_ti												RHEA:22576|EC:3.1.1.81|MetaCyc:3.1.1.81-RXN|Reactome:R-HSA-8932633		molecular_function											owl:Class	
GO:0046573	biolink:NamedThing	lactonohydrolase activity	Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group.	got7fsn_ti														molecular_function											owl:Class	
GO:0009420	biolink:NamedThing	bacterial-type flagellum filament	The long (approximately 20 nm), thin external structure of the bacterial-type flagellum, which acts as a propeller.	got7fsn_ti	flagellin-based flagellum filament|flagellar filament													cellular_component											owl:Class	
GO:0033757	biolink:NamedThing	glucoside 3-dehydrogenase activity	Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor.	got7fsn_ti	D-aldohexoside:acceptor 3-oxidoreductase|D-aldohexopyranoside dehydrogenase|hexopyranoside-cytochrome c oxidoreductase|D-aldohexoside:cytochrome c oxidoreductase|D-aldohexoside:(acceptor) 3-oxidoreductase											MetaCyc:GLUCOSIDE-3-DEHYDROGENASE-RXN|Wikipedia:Glucoside_3-dehydrogenase|RHEA:16589|EC:1.1.99.13		molecular_function											owl:Class	
GO:0071366	biolink:NamedThing	cellular response to indolebutyric acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.	got7fsn_ti	cellular response to IBA stimulus|cellular response to indole-3-butyric acid stimulus						mah	2009-12-11T03:12:14Z						biological_process											owl:Class	
GO:0009374	biolink:NamedThing	biotin binding	Binding to biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.	got7fsn_ti	vitamin H binding|vitamin B7 binding													molecular_function											owl:Class	
GO:0008390	biolink:NamedThing	testosterone 16-alpha-hydroxylase activity	Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O.	got7fsn_ti	cytochrome P450 CYP2D11|cytochrome P450 CYP2D10|cytochrome P450 CYP2B10|cytochrome P450 CYP2B9|cytochrome P450 CYP2D9													molecular_function											owl:Class	
GO:0008479	biolink:NamedThing	queuine tRNA-ribosyltransferase activity	Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.	got7fsn_ti	transfer ribonucleate glycosyltransferase activity|queuine transfer ribonucleate ribosyltransferase activity|Q-insertase activity|tRNA guanine transglycosidase activity|guanine, queuine-tRNA transglycosylase activity|tRNA-guanine transglycosylase activity|tRNA transglycosylase activity|guanine insertion enzyme activity|[tRNA]-guanine:queuine tRNA-D-ribosyltransferase activity											MetaCyc:QUEUOSINE-TRNA-RIBOSYLTRANSFERASE-RXN|RHEA:16633|Reactome:R-HSA-6782443|EC:2.4.2.29		molecular_function											owl:Class	
GO:0102450	biolink:NamedThing	kaempferide 7-O-methyltransferase activity	Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine  <=> 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13936		molecular_function											owl:Class	
GO:0072736	biolink:NamedThing	cellular response to tert-butyl hydroperoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.	got7fsn_ti	cellular response to 2-methyl-prop-2-yl-hydroperoxide|cellular response to t-BOOH						mah	2012-07-17T10:33:00Z						biological_process											owl:Class	
GO:0071817	biolink:NamedThing	MMXD complex	A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation.	got7fsn_ti	MMS19-MIP18-XPD complex						mah	2010-09-07T10:53:42Z						cellular_component											owl:Class	
GO:0044472	biolink:NamedThing	envenomation resulting in modulation of calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:17:25Z						biological_process											owl:Class	
GO:0008884	biolink:NamedThing	glutathionylspermidine amidase activity	Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine.	got7fsn_ti	gamma-L-glutamyl-L-cysteinyl-glycine:spermidine amidase activity|GSP amidase activity|glutathionylspermidine amidohydrolase (spermidine-forming) activity											EC:3.5.1.78|MetaCyc:GSPAMID-RXN|RHEA:17173		molecular_function											owl:Class	
GO:0016268	biolink:NamedThing	O-glycan processing, core 2	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.	got7fsn_ti														biological_process											owl:Class	
GO:0002701	biolink:NamedThing	negative regulation of production of molecular mediator of immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.	got7fsn_ti	down regulation of production of molecular mediator of immune response|downregulation of production of molecular mediator of immune response|inhibition of production of molecular mediator of immune response|down-regulation of production of molecular mediator of immune response													biological_process											owl:Class	
GO:0086054	biolink:NamedThing	bundle of His cell to Purkinje myocyte communication by electrical coupling	The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti	bundle of His cardiac muscle cell to Purkinje myocyte communication by electrical coupling						dph	2011-11-17T10:46:43Z						biological_process											owl:Class	
GO:0055081	biolink:NamedThing	anion homeostasis	Any process involved in the maintenance of an internal steady state of anions within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0045508	biolink:NamedThing	interleukin-26 receptor activity	Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-26 receptor activity|IL-26R													molecular_function											owl:Class	
GO:0005129	biolink:NamedThing	granulocyte macrophage colony-stimulating factor receptor binding	Binding to a granulocyte macrophage colony-stimulating factor receptor.	got7fsn_ti	granulocyte macrophage colony-stimulating factor receptor ligand|GMC-SF receptor ligand|GM-CSF receptor ligand|granulocyte macrophage colony stimulating factor receptor binding|GM-CSF receptor binding|granulocyte macrophage colony-stimulating factor													molecular_function											owl:Class	
GO:0010613	biolink:NamedThing	positive regulation of cardiac muscle hypertrophy	Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0097713	biolink:NamedThing	dolichol-phosphate-mannose synthase regulator activity	Binds to and modulates the activity of dolichol-phosphate-mannose synthase.	got7fsn_ti							pr	2016-08-23T11:19:37Z						molecular_function											owl:Class	
GO:0042667	biolink:NamedThing	auditory receptor cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	auditory hair cell fate specification													biological_process											owl:Class	
GO:0018155	biolink:NamedThing	peptide cross-linking via sn-(2S,6R)-lanthionine	The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione).	got7fsn_ti												RESID:AA0111		biological_process											owl:Class	
GO:2000381	biolink:NamedThing	negative regulation of mesoderm development	Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development.	got7fsn_ti							vk	2011-02-15T03:10:02Z						biological_process											owl:Class	
GO:0062120	biolink:NamedThing	LinE complex assembly	The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.	got7fsn_ti							dph	2019-03-19T14:14:25Z						biological_process											owl:Class	
GO:0046034	biolink:NamedThing	ATP metabolic process	The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.	got7fsn_ti	ATP metabolism													biological_process											owl:Class	
GO:0097078	biolink:NamedThing	FAL1-SGD1 complex	A protein complex involved in the 18S rRNA biogenesis. In S. cerevisiae this complex consists of Fal1p and Sgd1p and in humans this complex consists of NOM1 and eIF4AIII subunits.	got7fsn_ti							pr	2011-06-17T09:59:10Z						cellular_component											owl:Class	
GO:0060083	biolink:NamedThing	smooth muscle contraction involved in micturition	The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.	got7fsn_ti	urinary bladder smooth muscle contraction involved in micturition|smooth muscle contraction involved in urination													biological_process											owl:Class	
GO:0047221	biolink:NamedThing	sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP.	got7fsn_ti	floridoside-phosphate synthase activity|floridoside phosphate synthetase activity|UDP-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity|UDP-galactose:sn-glycerol-3-phosphate-2-D-galactosyl transferase activity|UDP-galactose, sn-3-glycerol phosphate:1->2' galactosyltransferase activity|floridoside phosphate synthase activity|UDPgalactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity|FPS											MetaCyc:2.4.1.137-RXN|RHEA:14285|KEGG_REACTION:R00853|EC:2.4.1.137		molecular_function											owl:Class	
GO:0008809	biolink:NamedThing	carnitine racemase activity	Catalysis of the reaction: D-carnitine = L-carnitine.	got7fsn_ti												MetaCyc:CARNRACE-RXN		molecular_function											owl:Class	
GO:0008754	biolink:NamedThing	O antigen ligase activity	Catalysis of the reaction: Lipid A-core + colanic acid = MLPS.	got7fsn_ti												MetaCyc:RXN0-5294		molecular_function											owl:Class	
GO:0018665	biolink:NamedThing	4-hydroxyphenylacetate 1-monooxygenase activity	Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O.	got7fsn_ti	4-hydroxyphenyl-acetate 1-hydroxylase activity|4-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating)|4-hydroxyphenylacetic 1-hydroxylase activity|4-hydroxyphenylacetate 1-hydroxylase activity|4-HPA 1-hydroxylase activity											EC:1.14.13.18|MetaCyc:1.14.13.18-RXN|UM-BBD_reactionID:r0300		molecular_function											owl:Class	
GO:0021974	biolink:NamedThing	trigeminothalamic tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.	got7fsn_ti														biological_process											owl:Class	
GO:0070997	biolink:NamedThing	neuron death	The process of cell death in a neuron.	got7fsn_ti	neuronal cell death|neuron cell death				This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate.		mah	2009-11-03T02:37:17Z						biological_process											owl:Class	
GO:0044523	biolink:NamedThing	envenomation resulting in damage of muscle extracellular matrix in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism.	got7fsn_ti	envenomation resulting in damage of muscle extracellular matrix causing muscle necrosis in other organism						jl	2012-02-27T12:40:32Z						biological_process											owl:Class	
GO:0015362	biolink:NamedThing	high-affinity sodium:dicarboxylate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity sodium:dicarboxylate cotransporter activity|high affinity sodium:dicarboxylate symporter activity											Reactome:R-HSA-433101		molecular_function											owl:Class	
GO:0050618	biolink:NamedThing	phycoerythrobilin:ferredoxin oxidoreductase activity	Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin.	got7fsn_ti	(3Z)-phycoerythrobilin:ferredoxin oxidoreductase activity|PebB											EC:1.3.7.3|MetaCyc:1.3.7.3-RXN|RHEA:22092		molecular_function											owl:Class	
GO:0042580	biolink:NamedThing	mannosome	A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction.	got7fsn_ti														cellular_component											owl:Class	
GO:0050113	biolink:NamedThing	inositol oxygenase activity	Catalysis of the reaction: myo-inositol + O(2) = D-glucuronate + H(2)O + H(+).	got7fsn_ti	meso-inositol oxygenase activity|myo-inositol:oxygen oxidoreductase activity|myo-inositol oxygenase activity|MOO activity											KEGG_REACTION:R01184|RHEA:23696|MetaCyc:MYO-INOSITOL-OXYGENASE-RXN|Reactome:R-HSA-5678327|EC:1.13.99.1		molecular_function											owl:Class	
GO:0048726	biolink:NamedThing	labrum development	The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0012509	biolink:NamedThing	inter-Golgi transport vesicle membrane	The lipid bilayer surrounding a vesicle transporting substances within the Golgi.	got7fsn_ti	inter-Golgi transport constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0030663	biolink:NamedThing	COPI-coated vesicle membrane	The lipid bilayer surrounding a COPI-coated vesicle.	got7fsn_ti	COPI coated vesicle membrane													cellular_component											owl:Class	
GO:0035866	biolink:NamedThing	alphav-beta3 integrin-PKCalpha complex	A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha.	got7fsn_ti	alphav-beta3 integrin-protein kinase C alpha complex|alphav-beta3 integrin-PKCa complex						bf	2011-05-25T03:03:59Z						cellular_component											owl:Class	
GO:0044558	biolink:NamedThing	uterine smooth muscle relaxation	A process in which the extent of smooth muscle contraction is reduced in the uterus.	got7fsn_ti	smooth muscle relaxation of the uterus						jl	2012-04-05T02:57:11Z						biological_process											owl:Class	
GO:0021611	biolink:NamedThing	facial nerve formation	The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	got7fsn_ti	CN VII biosynthesis|CN VII formation													biological_process											owl:Class	
GO:0046304	biolink:NamedThing	2-nitropropane catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor.	got7fsn_ti	2-nitropropane catabolism|2-nitropropane breakdown|2-nitropropane degradation													biological_process											owl:Class	
GO:1904320	biolink:NamedThing	positive regulation of smooth muscle contraction involved in micturition	Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition.	got7fsn_ti	upregulation of urinary bladder smooth muscle contraction involved in micturition|up regulation of urinary bladder smooth muscle contraction involved in micturition|activation of urinary bladder smooth muscle contraction involved in micturition|up-regulation of smooth muscle contraction involved in urination|up-regulation of smooth muscle contraction involved in micturition|up-regulation of urinary bladder smooth muscle contraction involved in micturition|up regulation of smooth muscle contraction involved in urination|upregulation of smooth muscle contraction involved in micturition|activation of smooth muscle contraction involved in urination|activation of smooth muscle contraction involved in micturition|positive regulation of smooth muscle contraction involved in urination|positive regulation of urinary bladder smooth muscle contraction involved in micturition|up regulation of smooth muscle contraction involved in micturition|upregulation of smooth muscle contraction involved in urination						sl	2015-06-10T18:46:23Z						biological_process											owl:Class	
GO:0016072	biolink:NamedThing	rRNA metabolic process	The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.	got7fsn_ti	rRNA metabolism													biological_process											owl:Class	
GO:0005026	biolink:NamedThing	transforming growth factor beta receptor activity, type II	Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor.	got7fsn_ti	type II TGF-beta receptor activity|type II transforming growth factor beta receptor activity|transforming growth factor beta ligand binding to type II receptor|type II TGFbeta receptor activity											Reactome:R-HSA-170843		molecular_function											owl:Class	
GO:0035345	biolink:NamedThing	regulation of hypoxanthine transport	Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of 6-hydroxypurine transport						bf	2010-03-04T10:42:04Z						biological_process											owl:Class	
GO:0032239	biolink:NamedThing	regulation of nucleobase-containing compound transport	Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport													biological_process											owl:Class	
GO:0102570	biolink:NamedThing	tyrosine:phenylpyruvate aminotransferase activity	Catalysis of the reaction: keto-phenylpyruvate + L-tyrosine  = L-phenylalanine  + 3-(4-hydroxyphenyl)pyruvate.	got7fsn_ti												MetaCyc:RXN-15200		molecular_function											owl:Class	
GO:0017193	biolink:NamedThing	N-terminal peptidyl-glycine acetylation	The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine.	got7fsn_ti												RESID:AA0046		biological_process											owl:Class	
GO:0003136	biolink:NamedThing	negative regulation of heart induction by canonical Wnt signaling pathway	Any canonical Wnt signaling that decreases the rate, frequency or extent of heart induction.	got7fsn_ti	negative regulation of heart induction by canonical Wnt-activated signaling pathway|negative regulation of cardioblast cell fate specification by Wnt receptor signaling pathway|negative regulation of heart induction by canonical Wnt receptor signaling pathway|negative regulation of heart induction by canonical Wnt receptor signalling pathway						tb	2009-09-22T03:26:17Z						biological_process											owl:Class	
GO:0009997	biolink:NamedThing	negative regulation of cardioblast cell fate specification	Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	suppression of cardioblast cell fate|downregulation of cardioblast cell fate specification|down-regulation of cardioblast cell fate specification|inhibition of cardioblast cell fate specification|down regulation of cardioblast cell fate specification										GO:0042687			biological_process											owl:Class	
GO:0030786	biolink:NamedThing	(RS)-norcoclaurine 6-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine.	got7fsn_ti	S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase activity											RHEA:19941|MetaCyc:2.1.1.128-RXN|EC:2.1.1.128		molecular_function											owl:Class	
GO:0033687	biolink:NamedThing	osteoblast proliferation	The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.	got7fsn_ti														biological_process											owl:Class	
GO:0043653	biolink:NamedThing	mitochondrial fragmentation involved in apoptotic process	The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.	got7fsn_ti	mitochondrial fragmentation involved in apoptosis|mitochondrial fission during apoptosis				Although most of the processes described under 'apoptotic mitochondrial changes' take place during the signaling phase of apoptosis, 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed there. It is still controversial whether this process is involved in the signaling phase of apoptosis or not, so it was placed under the more generic 'apoptotic mitochondrial changes' parent rather than linked to the signaling or the execution phase until further research clarifies the matter.									biological_process											owl:Class	
GO:0044343	biolink:NamedThing	canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate or frequency of pancreatic B cell proliferation. Pancreatic B cell are cells of the pancreas that secrete insulin.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in regulation of pancreatic B cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt receptor signalling pathway involved in regulation of pancreatic B cell proliferation|canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|canonical Wnt receptor signalling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of type B pancreatic cell proliferation						jl	2010-08-25T01:53:22Z						biological_process											owl:Class	
GO:0061670	biolink:NamedThing	evoked neurotransmitter secretion	Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential.	got7fsn_ti	stimulus-dependant neurotransmitter secretion						dph	2014-11-17T08:06:21Z						biological_process											owl:Class	
GO:0102637	biolink:NamedThing	5-aminolevulinate-CoA ligase activity	Catalysis of the reaction: 5-ammoniolevulinate + coenzyme A + ATP <=> 5-aminolevulinyl-CoA + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-15714		molecular_function											owl:Class	
GO:0002457	biolink:NamedThing	T cell antigen processing and presentation	The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	got7fsn_ti	T lymphocyte antigen processing and presentation|T-cell antigen processing and presentation|T-lymphocyte antigen processing and presentation													biological_process											owl:Class	
GO:0042952	biolink:NamedThing	beta-ketoadipate pathway	A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates.	got7fsn_ti	ortho-cleavage pathway													biological_process											owl:Class	
GO:0009749	biolink:NamedThing	response to glucose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.	got7fsn_ti	response to glucose stimulus													biological_process											owl:Class	
GO:0043881	biolink:NamedThing	mesaconyl-CoA hydratase activity	Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA.	got7fsn_ti	mesaconyl-coenzyme A hydratase activity|beta-methylmalyl-CoA dehydratase activity|mch				This function is part of an alternate glyoxylate cycle for acetate assimilation.									molecular_function											owl:Class	
GO:0034935	biolink:NamedThing	tetrachlorobenzene dioxygenase activity	Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0957		molecular_function											owl:Class	
GO:0036391	biolink:NamedThing	medial cortex septin ring	A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins.	got7fsn_ti							bf	2013-06-06T16:12:06Z						cellular_component											owl:Class	
GO:0000950	biolink:NamedThing	branched-chain amino acid catabolic process to alcohol via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.	got7fsn_ti	branched chain family amino acid catabolic process to alcohol via Ehrlich pathway													biological_process											owl:Class	
GO:0102089	biolink:NamedThing	dehydroscoulerine synthase activity	Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+.	got7fsn_ti												MetaCyc:RXN-10888		molecular_function											owl:Class	
GO:0060379	biolink:NamedThing	cardiac muscle cell myoblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.	got7fsn_ti	cardiac myoblast differentiation|myocardial precursor cell differentiation													biological_process											owl:Class	
GO:0097379	biolink:NamedThing	dorsal spinal cord interneuron posterior axon guidance	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	got7fsn_ti	dorsal interneuron caudal axon projection						pr	2012-10-01T10:22:38Z						biological_process											owl:Class	
GO:0072414	biolink:NamedThing	response to mitotic cell cycle checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling.	got7fsn_ti	mitotic cell cycle G1/S checkpoint effector process|response to signal involved in mitotic G2/M transition checkpoint|response to mitotic cell cycle G1/S checkpoint signaling|response to signal involved in mitotic cell cycle G1/S checkpoint|mitotic G2/M transition checkpoint effector process|response to signal involved in mitotic cell cycle checkpoint|mitotic cell cycle checkpoint effector process|response to mitotic G2/M transition checkpoint signal						mah	2010-12-08T03:50:43Z			GO:0072473|GO:0072455			biological_process											owl:Class	
GO:0005227	biolink:NamedThing	calcium activated cation channel activity	Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.	got7fsn_ti	intracellular calcium-activated potassium channel|polycystin													molecular_function											owl:Class	
GO:0050460	biolink:NamedThing	hydroxylamine reductase (NADH) activity	Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+.	got7fsn_ti	N-hydroxy amine reductase activity|ammonium dehydrogenase activity|NADH-hydroxylamine reductase activity|NADH2:hydroxylamine oxidoreductase activity|NADH:hydroxylamine oxidoreductase activity|ammonium:NAD+ oxidoreductase activity|hydroxylamine reductase (NADH2)											MetaCyc:HYDROXYLAMINE-REDUCTASE-NADH-RXN|EC:1.7.1.10|RHEA:20581		molecular_function											owl:Class	
GO:1990112	biolink:NamedThing	RQC complex	A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.	got7fsn_ti	ribosome quality control complex|ribosome-bound quality control complex						rb	2013-05-31T21:42:43Z						cellular_component											owl:Class	
GO:0019108	biolink:NamedThing	aryl-aldehyde dehydrogenase (NAD) activity	Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+.	got7fsn_ti	aryl-aldehyde:NAD+ oxidoreductase activity											UM-BBD_reactionID:r0394|MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-RXN|RHEA:11804|EC:1.2.1.29		molecular_function											owl:Class	
GO:0031121	biolink:NamedThing	equatorial microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell.	got7fsn_ti	equatorial microtubule organisation|equatorial microtubule organization and biogenesis													biological_process											owl:Class	
GO:0019466	biolink:NamedThing	ornithine catabolic process via proline	The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline.	got7fsn_ti	ornithine breakdown via proline|ornithine degradation via proline											MetaCyc:ORN-AMINOPENTANOATE-CAT-PWY		biological_process											owl:Class	
GO:0051519	biolink:NamedThing	activation of bipolar cell growth	Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0051518	biolink:NamedThing	positive regulation of bipolar cell growth	Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.	got7fsn_ti	upregulation of bipolar cell growth|up-regulation of bipolar cell growth|up regulation of bipolar cell growth|stimulation of bipolar cell growth													biological_process											owl:Class	
GO:0018343	biolink:NamedThing	protein farnesylation	The covalent attachment of a farnesyl group to a protein.	got7fsn_ti	C-terminal protein farnesylation|protein amino acid farnesylation										GO:0018347			biological_process											owl:Class	
GO:0019732	biolink:NamedThing	antifungal humoral response	An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.	got7fsn_ti											GO:0019734|GO:0006966			biological_process											owl:Class	
GO:0051785	biolink:NamedThing	positive regulation of nuclear division	Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.	got7fsn_ti	activation of nuclear division|up regulation of nuclear division|stimulation of nuclear division|up-regulation of nuclear division|upregulation of nuclear division													biological_process											owl:Class	
GO:0106348	biolink:NamedThing	U2 snRNA adenosine m6 methytransferase activity	Catalysis of the reaction: a adenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-adenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.	got7fsn_ti							hjd	2020-12-18T15:12:57Z						molecular_function											owl:Class	
GO:0086017	biolink:NamedThing	Purkinje myocyte action potential	An action potential that occurs in a Purkinje myocyte.	got7fsn_ti							tb	2011-11-10T08:58:56Z						biological_process											owl:Class	
GO:0071351	biolink:NamedThing	cellular response to interleukin-18	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.	got7fsn_ti	cellular response to IL-18						mah	2009-12-11T02:50:03Z						biological_process											owl:Class	
GO:0070673	biolink:NamedThing	response to interleukin-18	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.	got7fsn_ti	response to IL-18						mah	2009-05-29T10:03:52Z						biological_process											owl:Class	
GO:0140700	biolink:NamedThing	3',2'-cyclic GMP-AMP synthase activity	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(2'-5') (cyclic 3',2' GAMP).	got7fsn_ti	3',2' cyclic-GMP-AMP synthase activity|3',2'-cyclic GAMP synthase activity	https://github.com/geneontology/go-ontology/issues/21980					pg	2021-08-27T05:11:54Z						molecular_function											owl:Class	
GO:0140699	biolink:NamedThing	cyclic GMP-AMP synthase activity	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP.	got7fsn_ti	cyclic-GMP-AMP synthase activity	https://github.com/geneontology/go-ontology/issues/21980			Note that this term should not be used for direct annotation. It should be possible to annotate to a more specific child term that descibes the position of the phosphate group on the cGAMP molecule.		pg	2021-08-27T05:05:37Z						molecular_function											owl:Class	
GO:0043831	biolink:NamedThing	thiosulfate dehydrogenase (quinone) activity	Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate.	got7fsn_ti	thiosulphate:quinone oxidoreductase activity|DoxA|thiosulfate:6-decylubiquinone oxidoreductase activity|thiosulphate dehydrogenase (quinone) activity|thiosulfate:quinone oxidoreductase activity|TQO|thiosulfate oxidoreductase, tetrathionate-forming activity|DoxD											MetaCyc:1.8.5.2-RXN|KEGG_REACTION:R07177|RHEA:10936|EC:1.8.5.2		molecular_function											owl:Class	
GO:0034360	biolink:NamedThing	chylomicron remnant	A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.	got7fsn_ti														cellular_component											owl:Class	
GO:0102573	biolink:NamedThing	aminodeoxyfutalosine synthase activity	Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine  + H2O <=> aminodeoxyfutalosinate + L-methionine  + hydrogencarbonate + H+.	got7fsn_ti												RHEA:33075|EC:2.5.1.120|MetaCyc:RXN-15264		molecular_function											owl:Class	
GO:0008158	biolink:NamedThing	hedgehog receptor activity	Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.	got7fsn_ti	patched activity													molecular_function											owl:Class	
GO:0052626	biolink:NamedThing	benzoate amino acid synthetase activity	Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate.	got7fsn_ti	benzoyl amino acid synthetase activity													molecular_function											owl:Class	
GO:0019479	biolink:NamedThing	L-alanine oxidation to D-lactate and ammonia	The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia.	got7fsn_ti												MetaCyc:ALACAT2-PWY		biological_process											owl:Class	
GO:0042853	biolink:NamedThing	L-alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.	got7fsn_ti	L-alanine breakdown|L-alanine degradation|L-alanine catabolism													biological_process											owl:Class	
GO:0005262	biolink:NamedThing	calcium channel activity	Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti												Reactome:R-HSA-3295579|Reactome:R-HSA-8949145|Reactome:R-HSA-139855|Reactome:R-HSA-210420|Reactome:R-HSA-139854|Reactome:R-HSA-8949178		molecular_function											owl:Class	
GO:0009946	biolink:NamedThing	proximal/distal axis specification	The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).	got7fsn_ti	proximal/distal axis determination|proximodistal axis specification													biological_process											owl:Class	
GO:0021686	biolink:NamedThing	cerebellar granular layer maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	got7fsn_ti														biological_process											owl:Class	
GO:0015297	biolink:NamedThing	antiporter activity	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).	got7fsn_ti	solute:solute antiporter activity|exchange transporter activity|exchanger|porter|countertransporter activity|antiport|ion antiporter activity|solute:solute exchange										GO:0015300|GO:0099516	Reactome:R-HSA-2731002|Reactome:R-HSA-2730959|Reactome:R-HSA-2730692		molecular_function											owl:Class	
GO:0033656	biolink:NamedThing	modification by symbiont of host chloroplast	The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0090511	biolink:NamedThing	periclinal cell division	A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file.	got7fsn_ti							tb	2012-11-21T11:52:40Z						biological_process											owl:Class	
GO:0099639	biolink:NamedThing	neurotransmitter receptor transport, endosome to plasma membrane	The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:0050198	biolink:NamedThing	pinosylvin synthase activity	Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO(2) + 4 CoA + pinosylvin.	got7fsn_ti	malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)|pine stilbene synthase activity|stilbene synthase activity											KEGG_REACTION:R02505|MetaCyc:PINOSYLVIN-SYNTHASE-RXN|EC:2.3.1.146|RHEA:12552		molecular_function											owl:Class	
GO:0004154	biolink:NamedThing	dihydropterin oxidase activity	Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide.	got7fsn_ti														molecular_function											owl:Class	
GO:0035860	biolink:NamedThing	glial cell-derived neurotrophic factor receptor signaling pathway	The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands.	got7fsn_ti	glial cell-derived neurotrophic factor receptor signalling pathway|glial cell derived neurotrophic factor receptor signaling pathway|glial cell line-derived neurotrophic factor receptor signalling pathway|GDNF receptor signaling pathway						bf	2011-05-17T11:01:33Z						biological_process											owl:Class	
GO:0004824	biolink:NamedThing	lysine-tRNA ligase activity	Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).	got7fsn_ti	lysine translase activity|L-lysine:tRNALys ligase (AMP-forming)|L-lysine-transfer RNA ligase activity|lysyl-transfer ribonucleate synthetase activity|lysine-tRNA synthetase activity|lysyl-tRNA synthetase activity|lysyl-transfer RNA synthetase activity											Reactome:R-HSA-380008|Reactome:R-HSA-380233|EC:6.1.1.6|RHEA:20792|MetaCyc:LYSINE--TRNA-LIGASE-RXN		molecular_function											owl:Class	
GO:0090516	biolink:NamedThing	L-serine transmembrane import into vacuole	The directed movement of L-serine into the vacuole across the vacuolar membrane.	got7fsn_ti							tb	2012-12-14T11:25:52Z						biological_process											owl:Class	
GO:0034491	biolink:NamedThing	neutral amino acid transmembrane import into vacuole	The directed movement of neutral amino acids into the vacuole across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0018013	biolink:NamedThing	N-terminal peptidyl-glycine methylation	The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.	got7fsn_ti												RESID:AA0063		biological_process											owl:Class	
GO:0097181	biolink:NamedThing	protein C inhibitor-coagulation factor V complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V.	got7fsn_ti	protein C inhibitor-F5 complex|plasma serine protease inhibitor-coagulation factor V complex|serpin A5-coagulation factor V complex|PCI-coagulation factor V complex|SERPINA5-coagulation factor V complex						pr	2011-10-16T08:57:03Z						cellular_component											owl:Class	
GO:0003276	biolink:NamedThing	apoptotic process involved in heart valve morphogenesis	Any apoptotic process that contributes to the shaping of a heart valve.	got7fsn_ti	apoptosis involved in heart valve morphogenesis						dph	2009-10-20T09:34:29Z						biological_process											owl:Class	
GO:0003278	biolink:NamedThing	apoptotic process involved in heart morphogenesis	Any apoptotic process that contributes to the shaping of the heart.	got7fsn_ti	apoptosis involved in heart morphogenesis						dph	2009-10-20T09:40:22Z						biological_process											owl:Class	
GO:0018928	biolink:NamedThing	methyl ethyl ketone metabolic process	The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints.	got7fsn_ti	MEK metabolism|methyl ethyl ketone metabolism|MEK metabolic process|2-butanone metabolic process|2-butanone metabolism											UM-BBD_pathwayID:mek		biological_process											owl:Class	
GO:0004441	biolink:NamedThing	inositol-1,4-bisphosphate 1-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.	got7fsn_ti	1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase activity|inositol-polyphosphate 1-phosphatase activity|inositol polyphosphate 1-phosphatase activity											RHEA:15553|EC:3.1.3.57|Reactome:R-HSA-1855208|MetaCyc:3.1.3.57-RXN		molecular_function											owl:Class	
GO:0002332	biolink:NamedThing	transitional stage B cell differentiation	The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.	got7fsn_ti	transitional stage B lymphocyte differentiation|transitional stage B-cell differentiation|transitional stage B-lymphocyte differentiation|transitional stage B cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0002327	biolink:NamedThing	immature B cell differentiation	The process in which a precursor cell type acquires the specialized features of an immature B cell.	got7fsn_ti	immature B-cell differentiation|immature B lymphocyte differentiation|immature B-lymphocyte differentiation|immature B cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0048525	biolink:NamedThing	negative regulation of viral process	Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.	got7fsn_ti	negative regulation of viral reproduction|down regulation of viral life cycle|downregulation of viral life cycle|negative regulation of viral life cycle|inhibition of viral life cycle|down-regulation of viral life cycle													biological_process											owl:Class	
GO:0030877	biolink:NamedThing	beta-catenin destruction complex	A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.	got7fsn_ti	23S APC complex|BDC|beta-catenin degradation complex|APC-Axin-1-beta-catenin complex|Axin-APC-beta-catenin-GSK3B complex				Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.						GO:0034747|GO:0034742			cellular_component											owl:Class	
GO:0000833	biolink:NamedThing	inositol heptakisphosphate 4-kinase activity	Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate.	got7fsn_ti	diphosphoinositol-pentakisphosphate 4-kinase activity|IP7 4-kinase activity													molecular_function											owl:Class	
GO:0008874	biolink:NamedThing	gluconate 5-dehydrogenase activity	Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+.	got7fsn_ti	5-keto-D-gluconate reductase|5-ketogluconate reductase activity|5-keto-D-gluconate 5-reductase activity|5-ketogluconate 5-reductase activity|D-gluconate:NAD(P)+ 5-oxidoreductase											MetaCyc:GLUCONATE-5-DEHYDROGENASE-RXN|EC:1.1.1.69		molecular_function											owl:Class	
GO:0008875	biolink:NamedThing	gluconate dehydrogenase activity	Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+.	got7fsn_ti														molecular_function											owl:Class	
GO:0018277	biolink:NamedThing	protein deamination	The removal of an amino group from a protein amino acid.	got7fsn_ti	protein amino acid deamination													biological_process											owl:Class	
GO:0018026	biolink:NamedThing	peptidyl-lysine monomethylation	The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.	got7fsn_ti												RESID:AA0076		biological_process											owl:Class	
GO:0061545	biolink:NamedThing	tyramine secretion	The regulated release of a tyramine by a cell.	got7fsn_ti							dph	2013-06-25T09:14:07Z						biological_process											owl:Class	
GO:0007639	biolink:NamedThing	homeostasis of number of meristem cells	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem.	got7fsn_ti														biological_process											owl:Class	
GO:0072271	biolink:NamedThing	metanephric short descending thin limb development	The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.	got7fsn_ti							mah	2010-03-30T03:16:25Z						biological_process											owl:Class	
GO:0015400	biolink:NamedThing	low-affinity secondary active ammonium transmembrane transporter activity	Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low affinity ammonium transmembrane transporter activity|low affinity secondary active ammonium transmembrane transporter activity													molecular_function											owl:Class	
GO:0036183	biolink:NamedThing	asperthecin catabolic process	The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.	got7fsn_ti	asperthecin degradation|asperthecin catabolism|asperthecin breakdown						bf	2012-04-16T11:36:38Z						biological_process											owl:Class	
GO:0030557	biolink:NamedThing	tRNA modification guide activity	Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0044635	biolink:NamedThing	positive regulation of complement activation, alternative pathway in other organism	Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.	got7fsn_ti							jl	2012-07-05T04:36:11Z						biological_process											owl:Class	
GO:0045958	biolink:NamedThing	positive regulation of complement activation, alternative pathway	Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway.	got7fsn_ti	positive regulation of complement cascade, alternative pathway|up-regulation of complement activation, alternative pathway|upregulation of complement activation, alternative pathway|up regulation of complement activation, alternative pathway|activation of complement activation, alternative pathway|stimulation of complement activation, alternative pathway													biological_process											owl:Class	
GO:0050359	biolink:NamedThing	tropomyosin kinase activity	Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin.	got7fsn_ti	STK|ATP:tropomyosin O-phosphotransferase activity|tropomyosin kinase (phosphorylating) activity											EC:2.7.11.28|MetaCyc:TROPOMYOSIN-KINASE-RXN		molecular_function											owl:Class	
GO:0018653	biolink:NamedThing	3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity	Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.	got7fsn_ti												UM-BBD_reactionID:r0046|EC:1.14.13.-		molecular_function											owl:Class	
GO:0047738	biolink:NamedThing	cellobiose phosphorylase activity	Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose.	got7fsn_ti	cellobiose:phosphate alpha-D-glucosyltransferase activity											MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN|EC:2.4.1.20|RHEA:19493		molecular_function											owl:Class	
GO:0120063	biolink:NamedThing	stomach smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach.	got7fsn_ti							krc	2017-06-13T22:20:16Z						biological_process											owl:Class	
GO:0035901	biolink:NamedThing	cellular response to isolation stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.	got7fsn_ti	cellular response to social isolation						bf	2011-06-22T09:43:34Z						biological_process											owl:Class	
GO:0035900	biolink:NamedThing	response to isolation stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.	got7fsn_ti	response to social isolation						bf	2011-06-22T09:39:57Z						biological_process											owl:Class	
GO:0050296	biolink:NamedThing	stipitatonate decarboxylase activity	Catalysis of the reaction: H(2)O + stipitatonate = CO(2) + H(+) + stipitatate.	got7fsn_ti	stipitatonate carboxy-lyase (decyclizing, stipitatate-forming)|stipitatonate carboxy-lyase (decyclizing)											MetaCyc:STIPITATONATE-DECARBOXYLASE-RXN|RHEA:13885|EC:4.1.1.60|KEGG_REACTION:R03739		molecular_function											owl:Class	
GO:0018148	biolink:NamedThing	RNA-protein covalent cross-linking via peptidyl-tyrosine	The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine.	got7fsn_ti												RESID:AA0249		biological_process											owl:Class	
GO:1990638	biolink:NamedThing	response to granulocyte colony-stimulating factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.	got7fsn_ti	response to G-CSF						sl	2015-02-11T00:02:33Z						biological_process											owl:Class	
GO:0048046	biolink:NamedThing	apoplast	The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.	got7fsn_ti												Wikipedia:Apoplast		cellular_component											owl:Class	
GO:0050100	biolink:NamedThing	methylitaconate delta-isomerase activity	Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate.	got7fsn_ti	methylitaconate isomerase activity|methylitaconate delta2-delta3-isomerase activity|methylitaconate D-isomerase activity											MetaCyc:METHYLITACONATE-DELTA-ISOMERASE-RXN|KEGG_REACTION:R03070|RHEA:23480|EC:5.3.3.6		molecular_function											owl:Class	
GO:0004585	biolink:NamedThing	ornithine carbamoyltransferase activity	Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.	got7fsn_ti	L-ornithine transcarbamylase activity|L-ornithine carbamyltransferase activity|L-ornithine carbamoyltransferase activity|ornithine carbamyltransferase activity|carbamoyl-phosphate:L-ornithine carbamoyltransferase activity|carbamylphosphate-ornithine transcarbamylase activity|citrulline phosphorylase activity|ornithine transcarbamylase activity|OTC activity|OTCase activity											MetaCyc:RXN-13482|Reactome:R-HSA-70560|EC:2.1.3.3|RHEA:19513|MetaCyc:ORNCARBAMTRANSFER-RXN		molecular_function											owl:Class	
GO:0004605	biolink:NamedThing	phosphatidate cytidylyltransferase activity	Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol.	got7fsn_ti	CDP-diacylglycerol synthase activity|DAG synthetase activity|CTP:phosphatidate cytidylyltransferase activity|CDP-diglyceride synthetase activity|phosphatidic acid cytidylyltransferase activity|CDP-diglyceride diphosphorylase activity|CDP-diglyceride pyrophosphorylase activity|CTP-diacylglycerol synthetase activity|CDP-diacylglyceride synthetase activity|CDP-DG|phosphatidate cytidyltransferase activity|CDP diglyceride pyrophosphorylase activity|CTP:1,2-diacylglycerophosphate-cytidyl transferase activity|cytidine diphosphoglyceride pyrophosphorylase activity|CDP-diglyceride synthase activity											Reactome:R-HSA-1483121|RHEA:16229|EC:2.7.7.41|MetaCyc:CDPDIGLYSYN-RXN|Reactome:R-HSA-1483165		molecular_function											owl:Class	
GO:0019411	biolink:NamedThing	aerobic respiration, using ferrous ions as electron donor	The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.	got7fsn_ti														biological_process											owl:Class	
GO:0047618	biolink:NamedThing	acylagmatine amidase activity	Catalysis of the reaction: N(4)-benzoylagmatine + H(2)O = agmatine + benzoate.	got7fsn_ti	benzoylagmatine amidohydrolase activity|acylagmatine amidohydrolase activity|acylagmatine deacylase activity											KEGG_REACTION:R01425|MetaCyc:ACYLAGMATINE-AMIDASE-RXN|EC:3.5.1.40|RHEA:15065		molecular_function											owl:Class	
GO:0004830	biolink:NamedThing	tryptophan-tRNA ligase activity	Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp).	got7fsn_ti	TrpRS activity|tryptophanyl-tRNA synthase activity|tryptophanyl-transfer ribonucleic synthetase activity|tryptophanyl ribonucleic synthetase activity|tryptophanyl-transfer ribonucleate synthetase activity|tryptophanyl-tRNA synthetase activity|L-tryptophan:tRNATrp ligase (AMP-forming)|L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity|tryptophanyl-transfer RNA synthetase activity|tryptophanyl-transfer ribonucleic acid synthetase activity|L-tryptophan-tRNATrp ligase (AMP-forming)|tryptophan translase activity											RHEA:24080|Reactome:R-HSA-380222|Reactome:R-HSA-379977|EC:6.1.1.2|MetaCyc:TRYPTOPHAN--TRNA-LIGASE-RXN		molecular_function											owl:Class	
GO:0021538	biolink:NamedThing	epithalamus development	The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.	got7fsn_ti														biological_process											owl:Class	
GO:0106274	biolink:NamedThing	NAD+-protein-arginine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine.	got7fsn_ti							hjd	2020-07-02T01:37:02Z				EC:2.4.2.31|RHEA:19149		molecular_function											owl:Class	
GO:0102850	biolink:NamedThing	1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity	Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.23|MetaCyc:RXN-8316|RHEA:46376		molecular_function											owl:Class	
GO:0034919	biolink:NamedThing	butyryl-CoA 2-C-propionyltransferase activity	Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0931		molecular_function											owl:Class	
GO:0004801	biolink:NamedThing	transaldolase activity	Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.	got7fsn_ti	dihydroxyacetonetransferase activity|glycerone transferase activity|sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity|dihydroxyacetone transferase activity	https://github.com/geneontology/go-ontology/issues/20486										EC:2.2.1.2|Reactome:R-HSA-71334|MetaCyc:TRANSALDOL-RXN|Reactome:R-HSA-5659989|Reactome:R-HSA-5659998|Reactome:R-HSA-163764|RHEA:17053		molecular_function											owl:Class	
GO:0102735	biolink:NamedThing	trihydroxybenzophenone synthase activity	Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide.	got7fsn_ti												EC:2.3.1.220|RHEA:35143|MetaCyc:RXN-7481		molecular_function											owl:Class	
GO:0098868	biolink:NamedThing	bone growth	The increase in size or mass of a bone that contributes to the shaping of that bone.	got7fsn_ti														biological_process											owl:Class	
GO:0030200	biolink:NamedThing	heparan sulfate proteoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.	got7fsn_ti	heparan sulphate proteoglycan catabolic process|heparan sulfate proteoglycan catabolism|heparan sulfate proteoglycan degradation|heparan sulphate proteoglycan catabolism|heparin proteoglycan catabolic process|heparan sulfate proteoglycan breakdown													biological_process											owl:Class	
GO:0030167	biolink:NamedThing	proteoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	got7fsn_ti	proteoglycan degradation|proteoglycan catabolism|proteoglycan breakdown													biological_process											owl:Class	
GO:0106261	biolink:NamedThing	tRNA uridine(34) acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA = 5'-deoxyadenosine + carboxymethyluridine(34) in tRNA + CoA + 2 H(+) + L-methionine.	got7fsn_ti							hjd	2020-05-08T15:21:51Z				RHEA:61020		molecular_function											owl:Class	
GO:0010659	biolink:NamedThing	cardiac muscle cell apoptotic process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	got7fsn_ti	cardiac muscle cell apoptosis													biological_process											owl:Class	
GO:0010658	biolink:NamedThing	striated muscle cell apoptotic process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.	got7fsn_ti	striated muscle cell apoptosis													biological_process											owl:Class	
GO:0031475	biolink:NamedThing	myosin V complex	A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.	got7fsn_ti														cellular_component											owl:Class	
GO:0097570	biolink:NamedThing	cyst wall	The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins.	got7fsn_ti							pr	2014-02-18T10:25:53Z						cellular_component											owl:Class	
GO:0000450	biolink:NamedThing	cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)	Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species.	got7fsn_ti														biological_process											owl:Class	
GO:0019657	biolink:NamedThing	glycolytic fermentation to propionate	Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate.	got7fsn_ti	succinate-propionate fermentation											MetaCyc:P108-PWY		biological_process											owl:Class	
GO:0035040	biolink:NamedThing	sperm nuclear envelope removal	Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus.	got7fsn_ti														biological_process											owl:Class	
GO:0002562	biolink:NamedThing	somatic diversification of immune receptors via germline recombination within a single locus	The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.	got7fsn_ti														biological_process											owl:Class	
GO:1900541	biolink:NamedThing	fumonisin biosynthetic process	The chemical reactions and pathways resulting in the formation of fumonisin.	got7fsn_ti	fumonisin synthesis|fumonisin formation|fumonisin anabolism|fumonisin biosynthesis						tb	2012-05-11T12:54:37Z						biological_process											owl:Class	
GO:0106035	biolink:NamedThing	protein maturation by [4Fe-4S] cluster transfer	The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.	got7fsn_ti							hjd	2017-07-07T17:26:10Z						biological_process											owl:Class	
GO:0097428	biolink:NamedThing	protein maturation by iron-sulfur cluster transfer	The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.	got7fsn_ti							pr	2012-11-15T09:59:06Z						biological_process											owl:Class	
GO:0052808	biolink:NamedThing	reduced coenzyme F420:NADP+ oxidoreductase activity	Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.	got7fsn_ti	F420H2:NADP oxidoreductase activity|F420H2:NADP+ oxidoreductase activity|coenzyme F420-dependent NADP oxidoreductase activity|coenzyme F420-dependent NADP reductase activity|NADP+:F420 oxidoreductase activity						ai	2011-09-22T04:08:13Z				EC:1.5.1.40		molecular_function											owl:Class	
GO:0043983	biolink:NamedThing	histone H4-K12 acetylation	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.	got7fsn_ti	histone H4 acetylation at K12													biological_process											owl:Class	
GO:0033717	biolink:NamedThing	gluconate 2-dehydrogenase (acceptor) activity	Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.	got7fsn_ti	D-gluconate:acceptor 2-oxidoreductase activity|D-gluconate:(acceptor) 2-oxidoreductase activity|gluconic dehydrogenase activity|D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding activity|gluconic acid dehydrogenase activity|D-gluconate dehydrogenase activity|2-ketogluconate reductase activity|gluconate oxidase activity											EC:1.1.99.3|RHEA:12769|MetaCyc:GLUCONATE-2-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0004594	biolink:NamedThing	pantothenate kinase activity	Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.	got7fsn_ti	ATP:pantothenate 4'-phosphotransferase activity|D-pantothenate kinase activity|ATP:(R)-pantothenate 4'-phosphotransferase activity|pantothenate kinase (phosphorylating) activity|pantothenic acid kinase activity											MetaCyc:PANTOTHENATE-KIN-RXN|EC:2.7.1.33|Reactome:R-HSA-196857|RHEA:16373|Reactome:R-HSA-199203		molecular_function											owl:Class	
GO:0030945	biolink:NamedThing	protein tyrosine phosphatase activity, via thiol-phosphate intermediate	The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate.	got7fsn_ti														molecular_function											owl:Class	
GO:0043899	biolink:NamedThing	phosphoserine:homoserine phosphotransferase activity	Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine.	got7fsn_ti	thrH													molecular_function											owl:Class	
GO:1900593	biolink:NamedThing	violaceol II biosynthetic process	The chemical reactions and pathways resulting in the formation of violaceol II.	got7fsn_ti	violaceol II synthesis|violaceol II formation|violaceol II anabolism|violaceol II biosynthesis						di	2012-05-15T06:51:51Z						biological_process											owl:Class	
GO:0001802	biolink:NamedThing	type III hypersensitivity	An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.	got7fsn_ti					Note that the Arthus reaction is an example of type III hypersensitivity.							Wikipedia:Type_III_hypersensitivity		biological_process											owl:Class	
GO:0016064	biolink:NamedThing	immunoglobulin mediated immune response	An immune response mediated by immunoglobulins, whether cell-bound or in solution.	got7fsn_ti	antibody-mediated immune response													biological_process											owl:Class	
GO:0061100	biolink:NamedThing	lung neuroendocrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.	got7fsn_ti							dph	2010-04-27T03:28:46Z						biological_process											owl:Class	
GO:0018604	biolink:NamedThing	4-aminobenzoate 3,4-dioxygenase (deaminating) activity	Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate.	got7fsn_ti												UM-BBD_reactionID:r0566|EC:1.14.12.-		molecular_function											owl:Class	
GO:0018497	biolink:NamedThing	1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity	Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.	got7fsn_ti	DDMS dehydrogenase activity											UM-BBD_reactionID:r0514		molecular_function											owl:Class	
GO:0018475	biolink:NamedThing	trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity	Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid.	got7fsn_ti												UM-BBD_reactionID:r0745		molecular_function											owl:Class	
GO:0005132	biolink:NamedThing	type I interferon receptor binding	Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).	got7fsn_ti	interferon-alpha/beta receptor ligand|IFNAR1 binding|interferon-alpha/beta|IFNAR binding|IFNAR2 binding|interferon-alpha/beta receptor binding													molecular_function											owl:Class	
GO:0050510	biolink:NamedThing	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.	got7fsn_ti	N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity|chondroitin glucuronyltransferase II activity|alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase activity											MetaCyc:2.4.1.226-RXN|EC:2.4.1.226|Reactome:R-HSA-9632034|Reactome:R-HSA-1971491|Reactome:R-HSA-3595178		molecular_function											owl:Class	
GO:0033544	biolink:NamedThing	fatty acid beta-oxidation, unsaturated, even number, epimerase pathway	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	got7fsn_ti														biological_process											owl:Class	
GO:0102986	biolink:NamedThing	trehalose synthase activity	Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucopyranose <=> alpha,alpha-trehalose + H+ + a nucleoside diphosphate.	got7fsn_ti												MetaCyc:RXN-9603|EC:2.4.1.245|RHEA:47416		molecular_function											owl:Class	
GO:0019598	biolink:NamedThing	(R)-mandelate catabolic process to catechol	The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol.	got7fsn_ti	(R)-mandelate breakdown to catechol|(R)-mandelate degradation to catechol													biological_process											owl:Class	
GO:0050186	biolink:NamedThing	phosphoadenylylsulfatase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate.	got7fsn_ti	3-phosphoadenosine 5-phosphosulfate sulfatase activity|3-phosphoadenylyl sulfatase activity|3'-phosphoadenylylsulfate sulfohydrolase activity|PAPS sulfatase activity|phosphoadenylylsulphatase activity											RHEA:11232|EC:3.6.2.2|MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN		molecular_function											owl:Class	
GO:0016819	biolink:NamedThing	hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides	Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-.	got7fsn_ti	hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides											EC:3.6.2.-		molecular_function											owl:Class	
GO:0060514	biolink:NamedThing	prostate induction	The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.	got7fsn_ti														biological_process											owl:Class	
GO:0060685	biolink:NamedThing	regulation of prostatic bud formation	Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.	got7fsn_ti							dph	2009-06-05T12:29:26Z						biological_process											owl:Class	
GO:0080151	biolink:NamedThing	positive regulation of salicylic acid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction.	got7fsn_ti	positive regulation of salicylic acid mediated signalling pathway						dhl	2010-05-20T03:10:46Z						biological_process											owl:Class	
GO:0007531	biolink:NamedThing	mating type determination	Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms.	got7fsn_ti														biological_process											owl:Class	
GO:0102758	biolink:NamedThing	very-long-chain enoyl-CoA reductase activity	Catalysis of the reaction: NADP(3-) + a very-long-chain 2,3,4-saturated fatty acyl CoA <=> NADPH(4-) + H+ + a very-long-chain trans-2,3-dehydroacyl-CoA.	got7fsn_ti												EC:1.3.1.93|MetaCyc:RXN-7711|RHEA:14473		molecular_function											owl:Class	
GO:0048279	biolink:NamedThing	vesicle fusion with endoplasmic reticulum	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.	got7fsn_ti	vesicle fusion with ER													biological_process											owl:Class	
GO:0039592	biolink:NamedThing	suppression by virus of G2/M transition of host mitotic cell cycle	Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle.	got7fsn_ti	host G2/M cell cycle arrest by virus						bf	2012-06-25T02:07:18Z				VZ:876		biological_process											owl:Class	
GO:0060153	biolink:NamedThing	modulation by virus of host cell cycle	Any viral process that modulates the rate or extent of progression through the cell cycle.	got7fsn_ti	viral process regulating host cell cycle|regulation by virus of host cell cycle|modulation of host cell cycle by virus|regulation of host cell cycle by virus											VZ:1636		biological_process											owl:Class	
GO:0060954	biolink:NamedThing	neural crest-derived cardiac glial cell development	The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti							dph	2009-09-29T03:14:15Z						biological_process											owl:Class	
GO:0032617	biolink:NamedThing	interleukin-14 production	The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-14 biosynthetic process|interleukin-14 secretion|IL-14 production										GO:0072612|GO:0042232			biological_process											owl:Class	
GO:0061430	biolink:NamedThing	bone trabecula morphogenesis	The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.	got7fsn_ti							dph	2012-02-07T10:15:36Z						biological_process											owl:Class	
GO:0150061	biolink:NamedThing	amylin receptor 3 signaling pathway	A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos.	got7fsn_ti	AMY3 signaling pathway						bc	2018-06-21T11:02:09Z						biological_process											owl:Class	
GO:0000917	biolink:NamedThing	division septum assembly	The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.	got7fsn_ti	division septum assembly involved in cell cycle cytokinesis involved in mitotic cell cycle|septin assembly and septum formation involved in mitotic cell cycle|formation of division septum involved in mitotic cell cycle|septation|septin assembly and septum biosynthesis involved in mitotic cell cycle|division septum formation involved in mitotic cell cycle|septin assembly and septum biosynthesis|formation of division septum|septin assembly and septum formation|mitotic division septum assembly|division septum formation involved in cell cycle cytokinesis involved in mitotic cell cycle|division septum formation involved in cell cycle cytokinesis|division septum formation|division septum assembly involved in cell cycle cytokinesis										GO:0071937|GO:1902411			biological_process											owl:Class	
GO:0030563	biolink:NamedThing	snRNA 2'-O-ribose methylation guide activity	Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule.	got7fsn_ti					Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. Note that this term may be useful for annotating snoRNAs.									molecular_function											owl:Class	
GO:0019341	biolink:NamedThing	dibenzo-p-dioxin catabolic process	The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.	got7fsn_ti	dibenzo-p-dioxin degradation|dibenzo-p-dioxin breakdown|dibenzo-p-dioxin catabolism											MetaCyc:P661-PWY		biological_process											owl:Class	
GO:0036297	biolink:NamedThing	interstrand cross-link repair	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.	got7fsn_ti	ICL repair						bf	2012-08-07T11:05:19Z						biological_process											owl:Class	
GO:0048291	biolink:NamedThing	isotype switching to IgG isotypes	The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.	got7fsn_ti	class switching to IgG isotypes|isotype switch recombination to IgG isotypes													biological_process											owl:Class	
GO:0004141	biolink:NamedThing	dethiobiotin synthase activity	Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO(2) = ADP + dethiobiotin + 4 H(+) + phosphate.	got7fsn_ti	7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming)|desthiobiotin synthase activity|DTB synthetase activity											KEGG_REACTION:R03182|EC:6.3.3.3|MetaCyc:DETHIOBIOTIN-SYN-RXN|RHEA:15805		molecular_function											owl:Class	
GO:0035572	biolink:NamedThing	N-terminal peptidyl-serine dimethylation	The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.	got7fsn_ti							bf	2010-08-06T02:00:17Z						biological_process											owl:Class	
GO:0003068	biolink:NamedThing	regulation of systemic arterial blood pressure by acetylcholine	The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter.	got7fsn_ti	blood pressure regulation by acetylcholine													biological_process											owl:Class	
GO:0097420	biolink:NamedThing	skein-like inclusion	Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin.	got7fsn_ti							pr	2012-11-06T20:58:35Z				NIF_Subcellular:nlx_subcell_20090103		cellular_component											owl:Class	
GO:0110093	biolink:NamedThing	nucleus lagging edge	The area of a motile nucleus furthest from the direction of movement.	got7fsn_ti							kmv	2018-02-14T22:56:12Z						cellular_component											owl:Class	
GO:1990341	biolink:NamedThing	thrombospondin complex	A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour.	got7fsn_ti							bhm	2014-03-21T14:27:07Z						cellular_component											owl:Class	
GO:0002780	biolink:NamedThing	antibacterial peptide biosynthetic process	The chemical reactions and pathways resulting in the formation of an antibacterial peptide.	got7fsn_ti														biological_process											owl:Class	
GO:0047616	biolink:NamedThing	acyl-CoA dehydrogenase (NADP+) activity	Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+.	got7fsn_ti	2-enoyl-CoA reductase activity|acyl-CoA:NADP+ 2-oxidoreductase activity|dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate)|crotonyl coenzyme A reductase activity|enoyl coenzyme A reductase activity											RHEA:22460|MetaCyc:ACYL-COA-DEHYDROGENASE-NADP+-RXN|EC:1.3.1.8		molecular_function											owl:Class	
GO:0015475	biolink:NamedThing	adhesin autotransporter activity	Enables the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively.	got7fsn_ti														molecular_function											owl:Class	
GO:0140295	biolink:NamedThing	pathogen-derived receptor ligand activity	The activity of a pathogen-derived entity that interacts with a host receptor to activate effector-triggered immunity.	got7fsn_ti	innate receptor ligand activity	https://github.com/geneontology/go-ontology/issues/16656|https://github.com/geneontology/go-ontology/issues/19194			Note that this term is meant to annotate effectors for which the evolved activity is to act as a ligand to activate (for necrotrophs) or suppress (for biotrophs) the host immune system. It should not be used to annotate PAMPs (pathogen-associated molecular pattern molecules) or similar types of microbial proteins recognized by the host innate immune system (for example, PAMPs are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals). PAMPs activate innate immune responses, protecting the host from infection, but this is not the molecular function of PAMPs; those usually form the structure of the bacterial cell wall.		pg	2018-11-26T13:30:21Z						molecular_function											owl:Class	
GO:0051225	biolink:NamedThing	spindle assembly	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.	got7fsn_ti	bipolar spindle formation|bipolar spindle biosynthesis|spindle biosynthesis|spindle formation										GO:0051226|GO:0051227			biological_process											owl:Class	
GO:0048183	biolink:NamedThing	activin AB complex	A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B.	got7fsn_ti	inhibin beta-B|inhibin beta-A				Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'.									cellular_component											owl:Class	
GO:0018203	biolink:NamedThing	peptidyl-isoleucine modification	The modification of peptidyl-isoleucine.	got7fsn_ti														biological_process											owl:Class	
GO:0030888	biolink:NamedThing	regulation of B cell proliferation	Any process that modulates the frequency, rate or extent of B cell proliferation.	got7fsn_ti	regulation of B-lymphocyte proliferation|regulation of B lymphocyte proliferation|regulation of B-cell proliferation													biological_process											owl:Class	
GO:0016167	biolink:NamedThing	glial cell-derived neurotrophic factor receptor activity	Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	GDNF receptor activity|glial cell line-derived neurotrophic factor receptor activity													molecular_function											owl:Class	
GO:0001092	biolink:NamedThing	TFIIA-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.	got7fsn_ti	TFIIA-class transcription factor binding						krc	2010-10-28T02:37:19Z						molecular_function											owl:Class	
GO:0036012	biolink:NamedThing	cyanelle inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma.	got7fsn_ti	cyanelle inner envelope membrane						bf	2011-10-10T01:48:56Z						cellular_component											owl:Class	
GO:0014890	biolink:NamedThing	smooth muscle atrophy	A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.	got7fsn_ti														biological_process											owl:Class	
GO:0044510	biolink:NamedThing	envenomation resulting in positive regulation of signal transduction in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism.	got7fsn_ti							jl	2012-02-23T05:03:22Z						biological_process											owl:Class	
GO:0044509	biolink:NamedThing	envenomation resulting in modulation of signal transduction in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism.	got7fsn_ti							jl	2012-02-23T04:58:10Z						biological_process											owl:Class	
GO:0060480	biolink:NamedThing	lung goblet cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.	got7fsn_ti	pulmonary goblet cell differentiation													biological_process											owl:Class	
GO:0000476	biolink:NamedThing	maturation of 4.5S rRNA	Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0003129	biolink:NamedThing	heart induction	The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.	got7fsn_ti							tb	2009-09-22T02:58:41Z						biological_process											owl:Class	
GO:0097643	biolink:NamedThing	amylin receptor activity	Combining with amylin to initiate a change in cell activity.	got7fsn_ti							pr	2014-09-08T15:34:16Z						molecular_function											owl:Class	
GO:0051501	biolink:NamedThing	diterpene phytoalexin metabolic process	The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units.	got7fsn_ti	diterpene phytoalexin metabolism													biological_process											owl:Class	
GO:0045180	biolink:NamedThing	basal cortex	The region that lies just beneath the plasma membrane on the basal edge of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0080028	biolink:NamedThing	nitrile biosynthetic process	The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.	got7fsn_ti														biological_process											owl:Class	
GO:0106383	biolink:NamedThing	dAMP salvage	Any process which produces a dAMP from derivatives of it, without de novo synthesis.	got7fsn_ti							hjd	2021-06-11T16:51:09Z						biological_process											owl:Class	
GO:0048240	biolink:NamedThing	sperm capacitation	A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.	got7fsn_ti	sperm activation				Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract.									biological_process											owl:Class	
GO:0034559	biolink:NamedThing	bisphenol A hydroxylase B activity	Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O.	got7fsn_ti												UM-BBD_reactionID:r0860		molecular_function											owl:Class	
GO:0010473	biolink:NamedThing	GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity	Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol.	got7fsn_ti														molecular_function											owl:Class	
GO:0090017	biolink:NamedThing	anterior neural plate formation	The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate.	got7fsn_ti							tb	2009-07-29T11:31:35Z						biological_process											owl:Class	
GO:0103039	biolink:NamedThing	protein methylthiotransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine  + L-methionine  + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN0-6366|RHEA:37087|EC:2.8.4.4		molecular_function											owl:Class	
GO:0070823	biolink:NamedThing	HDA1 complex	A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.	got7fsn_ti							mah	2009-07-20T04:47:11Z						cellular_component											owl:Class	
GO:0008777	biolink:NamedThing	acetylornithine deacetylase activity	Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.	got7fsn_ti	N2-acetyl-L-ornithine amidohydrolase activity|2-N-acetyl-L-ornithine amidohydrolase activity|acetylornithinase activity|N-acetylornithinase activity											EC:3.5.1.16|MetaCyc:ACETYLORNDEACET-RXN|RHEA:15941		molecular_function											owl:Class	
GO:0102892	biolink:NamedThing	betanidin 5-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + betanin + UDP.	got7fsn_ti												MetaCyc:RXN-8479		molecular_function											owl:Class	
GO:0002023	biolink:NamedThing	reduction of food intake in response to dietary excess	An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients.	got7fsn_ti														biological_process											owl:Class	
GO:0050409	biolink:NamedThing	indolylacetylinositol arabinosyltransferase activity	Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP.	got7fsn_ti	UDP-L-arabinose:(indol-3-yl)acetyl-myo-inositol L-arabinosyltransferase activity|UDP-L-arabinose:indol-3-ylacetyl-myo-inositol L-arabinosyltransferase activity|arabinosylindolylacetylinositol synthase activity											MetaCyc:2.4.2.34-RXN|KEGG_REACTION:R04335|EC:2.4.2.34|RHEA:19505		molecular_function											owl:Class	
GO:0052636	biolink:NamedThing	arabinosyltransferase activity	Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor).	got7fsn_ti	arabinosyl transferase activity													molecular_function											owl:Class	
GO:0018883	biolink:NamedThing	caprolactam metabolic process	The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation.	got7fsn_ti	caprolactam metabolism											UM-BBD_pathwayID:cap		biological_process											owl:Class	
GO:0140034	biolink:NamedThing	methylation-dependent protein binding	Binding to a protein upon methylation of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require methylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of methylation. It may be that the methylation causes a conformational change that allows binding of the protein to another region; this type of methylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T15:40:02Z						molecular_function											owl:Class	
GO:0072588	biolink:NamedThing	box H/ACA RNP complex	A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex.	got7fsn_ti	sRNP complex|box H/ACA snoRNP pseudouridylase complex	https://github.com/geneontology/go-ontology/issues/20416					mah	2011-02-10T01:43:37Z						cellular_component											owl:Class	
GO:0007187	biolink:NamedThing	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.	got7fsn_ti	GPCR signaling pathway via cyclic nucleotide second messenger|G protein signaling, coupled to cyclic nucleotide second messenger|G-protein signalling, coupled to cyclic nucleotide second messenger|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|G-protein signaling, coupled to cyclic nucleotide second messenger|G protein signalling, coupled to cyclic nucleotide second messenger													biological_process											owl:Class	
GO:0003947	biolink:NamedThing	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide.	got7fsn_ti	ganglioside GM3 acetylgalactosaminyltransferase activity|GalNAc-T activity|ganglioside GM2 synthase activity|GM2 synthase activity|uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase activity|beta-1,4N-aetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase activity|UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase activity|GM2/GD2-synthase activity|UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase activity|asialo-GM2 synthase activity											MetaCyc:2.4.1.92-RXN|RHEA:12588|Reactome:R-HSA-8856223|EC:2.4.1.92		molecular_function											owl:Class	
GO:0018530	biolink:NamedThing	(R)-6-hydroxynicotine oxidase activity	Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).	got7fsn_ti	D-6-hydroxynicotine oxidase activity|(R)-6-hydroxynicotine:oxygen oxidoreductase activity|6-hydroxy-D-nicotine oxidase activity											MetaCyc:R-6-HYDROXYNICOTINE-OXIDASE-RXN|RHEA:10012|UM-BBD_reactionID:r0477|EC:1.5.3.6|KEGG_REACTION:R07170		molecular_function											owl:Class	
GO:0052650	biolink:NamedThing	NADP-retinol dehydrogenase activity	Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+.	got7fsn_ti	retinol:NADP+ oxidoreductase activity|NADP(H)-dependent retinol dehydrogenase/reductase activity|retinol dehydrogenase activity|all-trans-retinol dehydrogenase activity|retinol dehydrogenase [NADP+] activity|all-trans retinal reductase activity											Reactome:R-HSA-2471670|Reactome:R-HSA-5615668|KEGG_REACTION:R08379|Reactome:R-HSA-2465940|EC:1.1.1.300|Reactome:R-HSA-2466861|Reactome:R-HSA-2464803|MetaCyc:RXN-10841|Reactome:R-HSA-5419165|Reactome:R-HSA-2464822|Reactome:R-HSA-2465921|RHEA:25033|Reactome:R-HSA-5623643|Reactome:R-HSA-74872		molecular_function											owl:Class	
GO:0005600	biolink:NamedThing	collagen type XIII trimer	A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0098549	biolink:NamedThing	somatic ring canal	A stable intercellular bridge between somatic cells.  Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects.	got7fsn_ti														cellular_component											owl:Class	
GO:0071088	biolink:NamedThing	alpha5-beta1 integrin-tissue transglutaminase complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.	got7fsn_ti	ITGA5-ITGB1-TGM2 complex						mah	2009-11-06T04:45:47Z						cellular_component											owl:Class	
GO:0035988	biolink:NamedThing	chondrocyte proliferation	The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti	chondrocyte cell proliferation|cartilage cell proliferation						bf	2011-08-25T04:53:40Z						biological_process											owl:Class	
GO:0052072	biolink:NamedThing	induction by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|upregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|activation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|up regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|stimulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|upregulation by organism of defense-related host SA-mediated signal transduction pathway|positive regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|induction by organism of defense-related host salicylic acid-mediated signal transduction pathway|up-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|induction by organism of defense-related host SA-mediated signal transduction pathway|activation by organism of defense-related host salicylic acid-mediated signal transduction pathway|activation by organism of defense-related host SA-mediated signal transduction pathway|upregulation by organism of defense-related host salicylic acid-mediated signal transduction pathway|positive regulation by organism of defense-related host SA-mediated signal transduction pathway										GO:0052270			biological_process											owl:Class	
GO:1990328	biolink:NamedThing	RPB4-RPB7 complex	A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways.	got7fsn_ti	RNA polymerase II, RPB4-RPB7 subcomplex	https://github.com/geneontology/go-ontology/issues/10931					bhm	2014-03-17T09:37:07Z						cellular_component											owl:Class	
GO:0008134	biolink:NamedThing	transcription factor binding	Binding to a transcription factor, a protein required to initiate or regulate transcription.	got7fsn_ti	TF binding	https://github.com/geneontology/go-ontology/issues/19354			Note that this term should not be used for direct annotation. Please consier one of the more specific descendants, GO:0140297 ; DNA-binding transcription factor binding, GO:0140296 ; general transcription initiation factor binding or GO:0001221 ; transcription coregulator binding.									molecular_function											owl:Class	
GO:0019147	biolink:NamedThing	(R)-aminopropanol dehydrogenase activity	Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + H(+) + NADH.	got7fsn_ti	(R)-1-aminopropan-2-ol:NAD+ oxidoreductase activity|L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase activity|1-aminopropan-2-ol-NAD+ dehydrogenase activity|1-aminopropan-2-ol-dehydrogenase activity|DL-1-aminopropan-2-ol: NAD+ dehydrogenase activity|L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase activity|L-aminopropanol dehydrogenase activity											RHEA:16517|KEGG_REACTION:R03759|EC:1.1.1.75|MetaCyc:AMINOPROPDEHYDROG-RXN		molecular_function											owl:Class	
GO:0051976	biolink:NamedThing	lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.	got7fsn_ti	lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate|lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate											MetaCyc:PWY-3081		biological_process											owl:Class	
GO:0034827	biolink:NamedThing	1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r1171		molecular_function											owl:Class	
GO:0050166	biolink:NamedThing	pantoate 4-dehydrogenase activity	Catalysis of the reaction: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH.	got7fsn_ti	(R)-pantoate:NAD+ 4-oxidoreductase activity|pantoate dehydrogenase activity|panthothenase activity|D-pantoate:NAD+ 4-oxidoreductase activity											KEGG_REACTION:R02471|EC:1.1.1.106|RHEA:23000|MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0019401	biolink:NamedThing	alditol biosynthetic process	The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.	got7fsn_ti	alditol synthesis|alditol anabolism|alditol formation|alditol biosynthesis													biological_process											owl:Class	
GO:1900821	biolink:NamedThing	orlandin biosynthetic process	The chemical reactions and pathways resulting in the formation of orlandin.	got7fsn_ti	orlandin synthesis|orlandin anabolism|orlandin formation|orlandin biosynthesis						di	2012-06-04T10:15:24Z						biological_process											owl:Class	
GO:0042602	biolink:NamedThing	riboflavin reductase (NADPH) activity	Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.	got7fsn_ti	riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|reduced-riboflavin:NADP+ oxidoreductase activity|NADPH:riboflavin oxidoreductase activity|riboflavine mononucleotide reductase activity|riboflavin mononucleotide reductase activity|NADPH-riboflavin oxidoreductase activity|NADPH-specific FMN reductase activity|NADPH-FMN reductase activity|NADPH2 dehydrogenase (riboflavin)|NADPH-dependent FMN reductase activity|NADPH2:riboflavin oxidoreductase activity|NADPH-riboflavin reductase activity|flavin reductase activity|NADPH dehydrogenase (riboflavin) activity|FMN reductase (NADPH) activity											KEGG_REACTION:R05707|EC:1.5.1.41|MetaCyc:NADPH-DEHYDROGENASE-FLAVIN-RXN|EC:1.5.1.30|RHEA:19377		molecular_function											owl:Class	
GO:0044202	biolink:NamedThing	host cell nuclear outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes.	got7fsn_ti							jl	2009-10-21T11:10:23Z						cellular_component											owl:Class	
GO:0102435	biolink:NamedThing	myricetin 7-O-methyltransferase activity	Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine  <=> 7-O-methylmyricetin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13910		molecular_function											owl:Class	
GO:0044759	biolink:NamedThing	negative regulation by symbiont of host synaptic transmission	Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.	got7fsn_ti							jl	2012-12-06T15:37:25Z						biological_process											owl:Class	
GO:0021517	biolink:NamedThing	ventral spinal cord development	The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.	got7fsn_ti														biological_process											owl:Class	
GO:0090542	biolink:NamedThing	ELYC domain binding	Binding to a ELYC protein domain. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC.	got7fsn_ti							tb	2013-02-14T17:11:29Z						molecular_function											owl:Class	
GO:0018726	biolink:NamedThing	9-phenanthrol sulfotransferase activity	Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate.	got7fsn_ti	9-phenanthrol sulphotransferase activity											UM-BBD_reactionID:r0564		molecular_function											owl:Class	
GO:0019894	biolink:NamedThing	kinesin binding	Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.	got7fsn_ti														molecular_function											owl:Class	
GO:0102768	biolink:NamedThing	anthocyanidin synthase activity	Catalysis of the reaction: flavan-3,3',4,4',5,5',7-heptol + O2 + 2-oxoglutarate = H+ + delphinidin + 2 H2O + carbon dioxide + succinate.	got7fsn_ti												MetaCyc:RXN-7785		molecular_function											owl:Class	
GO:0009851	biolink:NamedThing	auxin biosynthetic process	The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.	got7fsn_ti	auxin formation|auxin biosynthesis|auxin synthesis|auxin anabolism													biological_process											owl:Class	
GO:0050324	biolink:NamedThing	taurocyamine kinase activity	Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+).	got7fsn_ti	ATP:taurocyamine phosphotransferase activity|taurocyamine phosphotransferase activity|ATP:taurocyamine N-phosphotransferase activity											EC:2.7.3.4|RHEA:22516|MetaCyc:TAUROCYAMINE-KINASE-RXN|KEGG_REACTION:R03785		molecular_function											owl:Class	
GO:0050054	biolink:NamedThing	lignostilbene alpha beta-dioxygenase activity	Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin.	got7fsn_ti	lignostilbene alphabeta-dioxygenase activity|lignostilbene ab-dioxygenase activity|1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alphabeta-bond-cleaving)											MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN|EC:1.13.11.43|RHEA:21340|KEGG_REACTION:R00043		molecular_function											owl:Class	
GO:0030954	biolink:NamedThing	astral microtubule nucleation	The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule.	got7fsn_ti														biological_process											owl:Class	
GO:0102987	biolink:NamedThing	palmitoleic acid delta 12 desaturase activity	Catalysis of the reaction: palmitoleoyl-CoA + O2 + a reduced electron acceptor <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												RHEA:45096|MetaCyc:RXN-9616		molecular_function											owl:Class	
GO:0008356	biolink:NamedThing	asymmetric cell division	The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.	got7fsn_ti	asymmetrical cell division|asymmetrical cytokinesis|asymmetric cytokinesis											Wikipedia:Asymmetric_cell_division		biological_process											owl:Class	
GO:0001540	biolink:NamedThing	amyloid-beta binding	Binding to an amyloid-beta peptide/protein.	got7fsn_ti	beta-amyloid binding	https://github.com/geneontology/go-ontology/issues/20109												molecular_function											owl:Class	
GO:0052793	biolink:NamedThing	pectin acetylesterase activity	Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin.	got7fsn_ti							ai	2011-10-05T05:17:21Z						molecular_function											owl:Class	
GO:0016688	biolink:NamedThing	L-ascorbate peroxidase activity	Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O.	got7fsn_ti	L-ascorbic acid peroxidase activity|L-ascorbic acid-specific peroxidase activity|L-ascorbate:hydrogen-peroxide oxidoreductase activity|ascorbic acid peroxidase activity|ascorbate peroxidase activity											MetaCyc:L-ASCORBATE-PEROXIDASE-RXN|RHEA:22996|EC:1.11.1.11		molecular_function											owl:Class	
GO:0070155	biolink:NamedThing	mitochondrial methionyl-tRNA aminoacylation	The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0050739	biolink:NamedThing	peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium	The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium.	got7fsn_ti												RESID:AA0348		biological_process											owl:Class	
GO:0140451	biolink:NamedThing	counting factor complex	A secreted multiprotein complex composed of 4 proteins, regulating group size during aggregation in cooperative development. An example of this complex is found in Dictyostelium discoideum.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19220					pg	2020-04-15T08:52:26Z						cellular_component											owl:Class	
GO:1902539	biolink:NamedThing	multi-organism macropinocytosis	A macropinocytosis which involves another organism.	got7fsn_ti							jl	2013-12-02T14:23:06Z						biological_process											owl:Class	
GO:0050077	biolink:NamedThing	maleylpyruvate isomerase activity	Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate.	got7fsn_ti	3-maleylpyruvate cis-trans-isomerase activity											RHEA:17393|MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN|EC:5.2.1.4		molecular_function											owl:Class	
GO:0003156	biolink:NamedThing	regulation of animal organ formation	Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.	got7fsn_ti							tb	2009-09-30T11:21:09Z						biological_process											owl:Class	
GO:0102830	biolink:NamedThing	verbascose synthase activity	Catalysis of the reaction: 2 stachyose <=> verbascose + raffinose.	got7fsn_ti												MetaCyc:RXN-8286		molecular_function											owl:Class	
GO:0052021	biolink:NamedThing	modulation by symbiont of ethylene levels in host	The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of ethylene levels in other organism involved in symbiotic interaction										GO:0052449			biological_process											owl:Class	
GO:0075202	biolink:NamedThing	regulation of penetration hypha formation	Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of symbiont penetration hypha formation for entry into host	https://github.com/geneontology/go-ontology/issues/21121			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0140067	biolink:NamedThing	peptidyl-lysine butyrylation	The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid.	got7fsn_ti							pg	2017-07-20T16:52:19Z						biological_process											owl:Class	
GO:1990849	biolink:NamedThing	maintenance of vacuolar location	Any process in which the vacuole is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of vacuole location|maintenance of vacuolar localization|maintenance of vacuole localization						mcc	2015-09-10T08:16:02Z						biological_process											owl:Class	
GO:0070618	biolink:NamedThing	Grb2-Sos complex	A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.	got7fsn_ti	Grb2-mSos1 complex						mah	2009-04-29T04:19:02Z						cellular_component											owl:Class	
GO:0016524	biolink:NamedThing	latrotoxin receptor activity	Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	latrophilin													molecular_function											owl:Class	
GO:0044379	biolink:NamedThing	protein localization to actin cortical patch	A process in which a protein is transported to, or maintained in, an actin cortical patch.	got7fsn_ti	protein localisation to actin cortical patch						jl	2011-12-08T02:28:42Z						biological_process											owl:Class	
GO:0102370	biolink:NamedThing	lupeol 28-monooxygenase activity	Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ <=> betulin + NADP(3-) + H2O.	got7fsn_ti												MetaCyc:RXN-13497		molecular_function											owl:Class	
GO:0048545	biolink:NamedThing	response to steroid hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.	got7fsn_ti	response to steroid hormone stimulus													biological_process											owl:Class	
GO:0033782	biolink:NamedThing	24-hydroxycholesterol 7alpha-hydroxylase activity	Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase].	got7fsn_ti	24-hydroxycholesterol 7alpha-monooxygenase activity|24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.14.13.99.							MetaCyc:1.14.13.99-RXN|KEGG_REACTION:R07208|EC:1.14.14.26|RHEA:46124		molecular_function											owl:Class	
GO:0006463	biolink:NamedThing	steroid hormone receptor complex assembly	The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor.	got7fsn_ti														biological_process											owl:Class	
GO:0075341	biolink:NamedThing	host cell PML body	A nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia) located within a cell of a host organism.	got7fsn_ti	host cell PML nuclear body|host cell PML NB													cellular_component											owl:Class	
GO:0102835	biolink:NamedThing	1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8295|EC:1.14.19.35		molecular_function											owl:Class	
GO:0004815	biolink:NamedThing	aspartate-tRNA ligase activity	Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).	got7fsn_ti	L-aspartate:tRNAAsp ligase (AMP-forming)|aspartyl ribonucleic synthetase activity|aspartyl-tRNA synthetase activity|aspartyl-transfer RNA synthetase activity|aspartyl ribonucleate synthetase activity|aspartic acid translase activity|aspartyl-transfer ribonucleic acid synthetase activity											MetaCyc:ASPARTATE--TRNA-LIGASE-RXN|Reactome:R-HSA-380229|Reactome:R-HSA-379867|EC:6.1.1.12|RHEA:19649		molecular_function											owl:Class	
GO:0030648	biolink:NamedThing	aminoglycoside antibiotic biosynthetic process	The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.	got7fsn_ti	aminoglycoside antibiotic anabolism|aminoglycoside antibiotic biosynthesis|aminoglycoside antibiotic synthesis|aminoglycoside antibiotic formation													biological_process											owl:Class	
GO:1900604	biolink:NamedThing	tensidol A catabolic process	The chemical reactions and pathways resulting in the breakdown of tensidol A.	got7fsn_ti	tensidol A degradation|tensidol A catabolism|tensidol A breakdown						di	2012-05-15T06:58:09Z						biological_process											owl:Class	
GO:0055122	biolink:NamedThing	response to very low light intensity stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.	got7fsn_ti														biological_process											owl:Class	
GO:0047793	biolink:NamedThing	cycloeucalenol cycloisomerase activity	Catalysis of the reaction: cycloeucalenol = obtusifoliol.	got7fsn_ti	cycloeucalenol lyase (cyclopropane-decyclizing)|cycloeucalenol--obtusifoliol isomerase activity|cycloeucalenol-obtusifoliol isomerase activity											MetaCyc:CYCLOEUCALENOL-CYCLOISOMERASE-RXN|EC:5.5.1.9|KEGG_REACTION:R03775|RHEA:22800		molecular_function											owl:Class	
GO:0015599	biolink:NamedThing	ATPase-coupled L-glutamine transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in).	got7fsn_ti	glutamine-importing ATPase activity|glutamine porter activity|ATPase-coupled glutamine transmembrane transporter activity											MetaCyc:ABC-12-RXN|EC:7.4.2.1		molecular_function											owl:Class	
GO:0015186	biolink:NamedThing	L-glutamine transmembrane transporter activity	Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.	got7fsn_ti	asparagine/glutamine permease activity													molecular_function											owl:Class	
GO:0021740	biolink:NamedThing	principal sensory nucleus of trigeminal nerve development	The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.	got7fsn_ti	pontine nucleus development				Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions.									biological_process											owl:Class	
GO:1990792	biolink:NamedThing	cellular response to glial cell derived neurotrophic factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.	got7fsn_ti	cellular response to astrocyte-derived trophic factor|cellular response to GDNF|cellular response to ATF						sl	2015-07-06T15:27:38Z						biological_process											owl:Class	
GO:0071542	biolink:NamedThing	dopaminergic neuron differentiation	The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.	got7fsn_ti							mah	2010-01-12T02:28:44Z						biological_process											owl:Class	
GO:0045128	biolink:NamedThing	negative regulation of reciprocal meiotic recombination	Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti	inhibition of meiotic recombination|down regulation of meiotic recombination|down-regulation of meiotic recombination|downregulation of meiotic recombination|suppression of meiotic recombination													biological_process											owl:Class	
GO:0045835	biolink:NamedThing	negative regulation of meiotic nuclear division	Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.	got7fsn_ti	downregulation of meiosis|down-regulation of meiosis|down regulation of meiosis|inhibition of meiosis|negative regulation of meiosis													biological_process											owl:Class	
GO:0080017	biolink:NamedThing	alpha-humulene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate.	got7fsn_ti												EC:4.2.3.104|RHEA:31895|MetaCyc:RXN-8415		molecular_function											owl:Class	
GO:0097648	biolink:NamedThing	G protein-coupled receptor complex	A protein complex that contains G protein-coupled receptors.	got7fsn_ti	G-protein coupled receptor complex						pr	2014-09-10T09:14:30Z						cellular_component											owl:Class	
GO:0021759	biolink:NamedThing	globus pallidus development	The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.	got7fsn_ti	pallidum development													biological_process											owl:Class	
GO:0004729	biolink:NamedThing	oxygen-dependent protoporphyrinogen oxidase activity	Catalysis of the reaction: 3 O(2) + protoporphyrinogen IX = 3 H(2)O(2) + protoporphyrin IX.	got7fsn_ti	protoporphyrinogen-IX:oxygen oxidoreductase activity											RHEA:25576|KEGG_REACTION:R03222|EC:1.3.3.4|Reactome:R-HSA-189423|MetaCyc:PROTOPORGENOXI-RXN		molecular_function											owl:Class	
GO:0050404	biolink:NamedThing	zeatin O-beta-D-xylosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H(+) + UDP.	got7fsn_ti	uridine diphosphoxylose-zeatin xylosyltransferase activity|zeatin O-b-D-xylosyltransferase activity|UDP-D-xylose:zeatin O-beta-D-xylosyltransferase activity|zeatin O-xylosyltransferase activity				Note that this function was formerly EC:2.4.1.204.							EC:2.4.2.40|KEGG_REACTION:R02119|RHEA:14721|MetaCyc:ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0035510	biolink:NamedThing	DNA dealkylation	The removal of an alkyl group from one or more nucleotides within an DNA molecule.	got7fsn_ti							bf	2010-04-30T02:20:08Z						biological_process											owl:Class	
GO:0102135	biolink:NamedThing	(22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity	Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 <=> (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-11530		molecular_function											owl:Class	
GO:0047712	biolink:NamedThing	Cypridina-luciferin 2-monooxygenase activity	Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.	got7fsn_ti	luciferase activity|luciferase (Cypridina luciferin)|Cypridina luciferase activity|Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)|Cypridina-type luciferase activity											EC:1.13.12.6|RHEA:22760|MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0030338	biolink:NamedThing	CMP-N-acetylneuraminate monooxygenase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.	got7fsn_ti	cytidine monophosphoacetylneuraminate monooxygenase activity|CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)|cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity|CMP-N-acetylneuraminic acid hydroxylase activity|CMP-N-acetylneuraminate hydroxylase activity|N-acetylneuraminic monooxygenase activity|CMP-Neu5Ac hydroxylase activity				Note that this was EC:1.14.13.45.							MetaCyc:1.14.13.45-RXN|RHEA:16145|EC:1.14.18.2		molecular_function											owl:Class	
GO:0030841	biolink:NamedThing	positive regulation of intermediate filament polymerization	Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization.	got7fsn_ti	positive regulation of intermediate filament polymerization and/or depolymerization|upregulation of intermediate filament polymerization|up regulation of intermediate filament polymerization|up-regulation of intermediate filament polymerization|activation of intermediate filament polymerization|stimulation of intermediate filament polymerization				Note that this term was split from 'positive regulation of intermediate filament polymerization and/or depolymerization ; GO:0045826' (sibling term 'positive regulation of intermediate filament depolymerization ; GO:0030844').									biological_process											owl:Class	
GO:0043888	biolink:NamedThing	(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity	Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate.	got7fsn_ti	UbiA|DGGGP synthase activity|2,3-dGGGPS|DGGGPS				This function is involved in archaeal lipid synthesis.							EC:2.5.1.-		molecular_function											owl:Class	
GO:0004337	biolink:NamedThing	geranyltranstransferase activity	Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.	got7fsn_ti	farnesyl-diphosphate synthase activity|geranyl transferase I|farnesylpyrophosphate synthetase activity|geranyltransferase activity|FPP synthetase activity|geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity|farnesyl pyrophosphate synthetase activity|farnesyl diphosphate synthetase activity				Note that this is the second step in the formation of farnesyl diphosphate. The first step is 'dimethylallyltransferase activity ; GO:0004161'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'.							Reactome:R-HSA-8870469|MetaCyc:FPPSYN-RXN|Reactome:R-HSA-191303|KEGG_REACTION:R02003|EC:2.5.1.10|RHEA:19361		molecular_function											owl:Class	
GO:0033960	biolink:NamedThing	N-methyl nucleosidase activity	Catalysis of the reaction: 7-methylxanthosine + H(2)O = 7-methylxanthine + H(+) + ribofuranose.	got7fsn_ti	methylpurine nucleosidase activity|N-methyl nucleoside hydrolase activity|N-MeNase activity|7-methylxanthosine ribohydrolase activity|7-methylxanthosine nucleosidase activity											MetaCyc:RXN-7597|KEGG_REACTION:R07918|RHEA:10880|EC:3.2.2.25		molecular_function											owl:Class	
GO:0060703	biolink:NamedThing	deoxyribonuclease inhibitor activity	Binds to and stops, prevents or reduces the activity of deoxyribonuclease.	got7fsn_ti	DNase inhibitor activity						dph	2009-06-08T03:00:35Z						molecular_function											owl:Class	
GO:0044805	biolink:NamedThing	late nucleophagy	A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM.	got7fsn_ti	LN						jl	2013-09-10T15:58:23Z						biological_process											owl:Class	
GO:0044804	biolink:NamedThing	autophagy of nucleus	A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.	got7fsn_ti	nucleophagy|nucleus degradation						jl	2013-09-10T15:50:25Z						biological_process											owl:Class	
GO:0036431	biolink:NamedThing	dCMP kinase activity	Catalysis of the reaction: ATP + dCMP = ADP + dCDP.	got7fsn_ti	ATP:dCMP phosphotransferase activity						bf	2013-09-16T14:11:56Z				RHEA:25094|MetaCyc:RXN-7913|KEGG_REACTION:R01665|MetaCyc:RXN-11831		molecular_function											owl:Class	
GO:0004127	biolink:NamedThing	cytidylate kinase activity	Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.	got7fsn_ti	CMP kinase activity|ATP:CMP phosphotransferase activity|CTP:CMP phosphotransferase activity|pyrimidine nucleoside monophosphate kinase activity|dCMP kinase activity|ATP:UMP-CMP phosphotransferase activity|deoxycytidylate kinase activity|deoxycytidine monophosphokinase activity|UMP-CMP kinase activity|cytidine monophosphate kinase activity											MetaCyc:CMPKI-RXN|EC:2.7.4.14		molecular_function											owl:Class	
GO:2000543	biolink:NamedThing	positive regulation of gastrulation	Any process that activates or increases the frequency, rate or extent of gastrulation.	got7fsn_ti							yaf	2011-04-01T04:10:15Z						biological_process											owl:Class	
GO:0002239	biolink:NamedThing	response to oomycetes	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.	got7fsn_ti														biological_process											owl:Class	
GO:0070421	biolink:NamedThing	DNA ligase III-XRCC1 complex	A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair.	got7fsn_ti														cellular_component											owl:Class	
GO:0015334	biolink:NamedThing	high-affinity oligopeptide transmembrane transporter activity	Enables the transfer of oligopeptide from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	got7fsn_ti	high affinity oligopeptide transporter activity|high-affinity oligopeptide transporter activity													molecular_function											owl:Class	
GO:0035673	biolink:NamedThing	oligopeptide transmembrane transporter activity	Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	got7fsn_ti	oligopeptide transporter activity						bf	2011-02-08T02:20:14Z			GO:0015198			molecular_function											owl:Class	
GO:0072449	biolink:NamedThing	response to G1 cell size control checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling.	got7fsn_ti	mitotic cell cycle G1/S transition size control checkpoint effector process|response to signal involved in mitotic cell cycle G1/S transition size control checkpoint						mah	2010-12-09T10:56:39Z						biological_process											owl:Class	
GO:0072470	biolink:NamedThing	response to cell size control checkpoint signaling	A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.	got7fsn_ti	response to mitotic cell cycle cell size control checkpoint signaling|cell size control checkpoint effector process|response to signal involved in cell size control checkpoint						mah	2010-12-09T11:46:13Z						biological_process											owl:Class	
GO:0034780	biolink:NamedThing	glyphosate dehydrogenase activity	Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0073		molecular_function											owl:Class	
GO:0047065	biolink:NamedThing	sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity	Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H(2)O.	got7fsn_ti	sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)|sulochrin oxidase activity											EC:1.21.3.5|RHEA:22616|KEGG_REACTION:R00061|MetaCyc:1.10.3.8-RXN		molecular_function											owl:Class	
GO:0019975	biolink:NamedThing	interleukin-17 binding	Binding to a member of the interleukin-17 family of cytokines.	got7fsn_ti	IL-17 binding													molecular_function											owl:Class	
GO:0005722	biolink:NamedThing	beta-heterochromatin	A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization.	got7fsn_ti														cellular_component											owl:Class	
GO:0019781	biolink:NamedThing	NEDD8 activating enzyme activity	Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.	got7fsn_ti	RUB1 activating enzyme activity										GO:0019944			molecular_function											owl:Class	
GO:0032578	biolink:NamedThing	aleurone grain membrane	The lipid bilayer surrounding an aleurone grain.	got7fsn_ti														cellular_component											owl:Class	
GO:0050472	biolink:NamedThing	zeatin reductase activity	Catalysis of the reaction: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin.	got7fsn_ti	dihydrozeatin:NADP+ oxidoreductase activity											KEGG_REACTION:R05702|MetaCyc:ZEATIN-REDUCTASE-RXN|EC:1.3.1.69|RHEA:12757		molecular_function											owl:Class	
GO:0060532	biolink:NamedThing	bronchus cartilage development	The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	got7fsn_ti	pulmonary cartilage development						dph	2009-04-10T08:12:06Z						biological_process											owl:Class	
GO:0034025	biolink:NamedThing	D-aspartate ligase activity	Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.	got7fsn_ti	aslfm|D-aspartic acid-activating enzyme|D-aspartate:[beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n ligase (ADP-forming) activity|UDP-MurNAc-pentapeptide:D-aspartate ligase activity											RHEA:10752|EC:6.3.1.12|MetaCyc:6.3.1.12-RXN		molecular_function											owl:Class	
GO:0005602	biolink:NamedThing	complement component C1 complex	A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains.	got7fsn_ti	complement component C1q complex													cellular_component											owl:Class	
GO:1901318	biolink:NamedThing	negative regulation of flagellated sperm motility	Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.	got7fsn_ti	inhibition of sperm motility|downregulation of sperm movement|down regulation of sperm movement|negative regulation of sperm movement|inhibition of sperm movement|down-regulation of sperm movement|downregulation of sperm motility|down-regulation of sperm motility|down regulation of sperm motility|negative regulation of sperm motility						hjd	2012-08-22T20:50:35Z						biological_process											owl:Class	
GO:0007506	biolink:NamedThing	gonadal mesoderm development	The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.	got7fsn_ti														biological_process											owl:Class	
GO:0002949	biolink:NamedThing	tRNA threonylcarbamoyladenosine modification	The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).	got7fsn_ti	t6A biosynthesis|threonylcarbamoyladenosine anabolism|t6A tRNA modification|threonylcarbamoyladenosine biosynthetic process|threonylcarbamoyladenosine formation|t6A biosynthetic process|threonylcarbamoyladenosine biosynthesis|threonylcarbamoyladenosine synthesis						hjd	2014-09-19T10:15:27Z			GO:0070526			biological_process											owl:Class	
GO:0047516	biolink:NamedThing	1,3-propanediol dehydrogenase activity	Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+.	got7fsn_ti	1,3-propanediol oxidoreductase activity|1,3-PD:NAD+ oxidoreductase activity|1,3-propanediol:NAD+ oxidoreductase activity|propane-1,3-diol:NAD+ 1-oxidoreductase activity|3-hydroxypropionaldehyde reductase activity											RHEA:23188|EC:1.1.1.202|MetaCyc:13-PROPANEDIOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0110135	biolink:NamedThing	Norrin signaling pathway	The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.	got7fsn_ti							kmv	2019-01-18T19:07:18Z						biological_process											owl:Class	
GO:1905114	biolink:NamedThing	cell surface receptor signaling pathway involved in cell-cell signaling	Any cell surface receptor signaling pathway that is involved in cell-cell signaling.	got7fsn_ti	cell surface receptor linked signalling pathway involved in cell-cell signalling|cell surface receptor linked signaling pathway involved in cell-cell signaling|cell surface receptor linked signal transduction involved in cell-cell signaling|cell surface receptor linked signalling pathway involved in cell-cell signaling|cell surface receptor linked signaling pathway involved in cell-cell signalling|cell surface receptor linked signal transduction involved in cell-cell signalling|cell surface receptor signaling pathway involved in cell-cell signalling						dos	2016-04-06T16:59:57Z						biological_process											owl:Class	
GO:0008360	biolink:NamedThing	regulation of cell shape	Any process that modulates the surface configuration of a cell.	got7fsn_ti											GO:0045788|GO:0045789			biological_process											owl:Class	
GO:0022604	biolink:NamedThing	regulation of cell morphogenesis	Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.	got7fsn_ti	positive regulation of cell shape and cell size|regulation of cell shape and cell size|negative regulation of cell shape and cell size													biological_process											owl:Class	
GO:0044737	biolink:NamedThing	modulation of acid-sensing ion channel in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism.	got7fsn_ti	regulation of acid-sensing ion channel in other organism|regulation of ASIC channel in other organism						jl	2012-11-06T16:51:24Z						biological_process											owl:Class	
GO:0004038	biolink:NamedThing	allantoinase activity	Catalysis of the reaction: allantoin + H2O = allantoate.	got7fsn_ti	(S)-allantoin amidohydrolase activity											MetaCyc:ALLANTOINASE-RXN|RHEA:17029|EC:3.5.2.5		molecular_function											owl:Class	
GO:0018814	biolink:NamedThing	phenylacetaldoxime dehydratase activity	Catalysis of the reaction: (trans)-phenylacetaldoxime = H(2)O + phenylacetonitrile.	got7fsn_ti	(Z)-phenylacetaldehyde-oxime hydro-lyase activity|OxdB|(Z)-phenylacetaldehyde-oxime hydro-lyase (phenylacetonitrile-forming) activity|PAOx dehydratase activity|arylacetaldoxime dehydratase activity											MetaCyc:4.99.1.7-RXN|KEGG_REACTION:R07638|EC:4.99.1.7|UM-BBD_reactionID:r0697|RHEA:20069		molecular_function											owl:Class	
GO:0071828	biolink:NamedThing	apolipoprotein E recycling	The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle.	got7fsn_ti	APOE recycling						mah	2010-09-08T11:05:15Z						biological_process											owl:Class	
GO:1990744	biolink:NamedThing	primary miRNA methylation	The posttranscriptional addition of methyl groups to specific residues in an primary miRNA molecule.	got7fsn_ti							sp	2015-05-15T05:18:47Z						biological_process											owl:Class	
GO:0036136	biolink:NamedThing	kynurenine-oxaloacetate transaminase activity	Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate.	got7fsn_ti	L-kynurenine-oxaloacetate transaminase activity						bf	2012-03-06T02:14:11Z						molecular_function											owl:Class	
GO:0018214	biolink:NamedThing	protein carboxylation	The addition of a carboxy group to a protein amino acid.	got7fsn_ti	protein amino acid carboxylation													biological_process											owl:Class	
GO:1990451	biolink:NamedThing	cellular stress response to acidic pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.	got7fsn_ti	cellular stress response to acidity				An example of this is NOX1 in human (Q9Y5S8) in PMID:10615049.		jl	2014-08-06T14:06:58Z						biological_process											owl:Class	
GO:0018529	biolink:NamedThing	nitrilotriacetate monooxygenase activity	Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.	got7fsn_ti												UM-BBD_reactionID:r0587|EC:1.14.14.10		molecular_function											owl:Class	
GO:2000117	biolink:NamedThing	negative regulation of cysteine-type endopeptidase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity.	got7fsn_ti	negative regulation of thiol endopeptidase activity|negative regulation of lysosomal cysteine-type endopeptidase						jl	2010-09-23T10:24:35Z						biological_process											owl:Class	
GO:0015311	biolink:NamedThing	monoamine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out).	got7fsn_ti	monoamine:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0060027	biolink:NamedThing	convergent extension involved in gastrulation	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.	got7fsn_ti														biological_process											owl:Class	
GO:0031257	biolink:NamedThing	cell trailing edge membrane	The portion of the plasma membrane surrounding the trailing edge of a motile cell.	got7fsn_ti	trailing edge membrane													cellular_component											owl:Class	
GO:0050757	biolink:NamedThing	thymidylate synthase biosynthetic process	The chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase, which catalyzes the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.	got7fsn_ti	thymidylate synthase formation|thymidylate synthase anabolism|thymidylate synthase biosynthesis|thymidylate synthase synthesis													biological_process											owl:Class	
GO:0070037	biolink:NamedThing	rRNA (pseudouridine) methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.	got7fsn_ti												Reactome:R-HSA-6790906		molecular_function											owl:Class	
GO:0007099	biolink:NamedThing	centriole replication	The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.	got7fsn_ti	ciliary basal body duplication|centriole duplication|microtubule basal body duplication										GO:0032054			biological_process											owl:Class	
GO:0102926	biolink:NamedThing	solanidine glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + solanidine = H+ + gamma-chaconine + UDP.	got7fsn_ti												MetaCyc:RXN-8882		molecular_function											owl:Class	
GO:0044323	biolink:NamedThing	retinoic acid-responsive element binding	Binding to a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind.	got7fsn_ti	RARE binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		jl	2010-08-03T03:19:05Z						molecular_function											owl:Class	
GO:0061923	biolink:NamedThing	(2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene.	got7fsn_ti	protoillud-7-ene synthase activity						dph	2017-08-02T15:48:21Z						molecular_function											owl:Class	
GO:0047847	biolink:NamedThing	deoxyuridine phosphorylase activity	Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate.	got7fsn_ti	deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity|deoxyuridine:phosphate deoxy-D-ribosyltransferase activity|2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity											MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN|EC:2.4.2.23|RHEA:22824		molecular_function											owl:Class	
GO:0045213	biolink:NamedThing	neurotransmitter receptor metabolic process	The chemical reactions and pathways involving neurotransmitter receptors.	got7fsn_ti	neurotransmitter receptor metabolism													biological_process											owl:Class	
GO:0021992	biolink:NamedThing	cell proliferation involved in neural plate elongation	The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0031919	biolink:NamedThing	vitamin B6 transport	The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0055100	biolink:NamedThing	adiponectin binding	Binding to adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism.	got7fsn_ti														molecular_function											owl:Class	
GO:0061377	biolink:NamedThing	mammary gland lobule development	The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.	got7fsn_ti							dph	2010-11-09T09:36:29Z						biological_process											owl:Class	
GO:1901678	biolink:NamedThing	iron coordination entity transport	The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							pr	2012-11-22T15:43:15Z						biological_process											owl:Class	
GO:0003168	biolink:NamedThing	Purkinje myocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.	got7fsn_ti	cardiac Purkinje fiber cell differentiation						dph	2009-10-01T02:49:54Z						biological_process											owl:Class	
GO:0002571	biolink:NamedThing	somatic diversification of T cell receptor genes by N region addition	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene.	got7fsn_ti	somatic diversification of TCR genes by N region addition													biological_process											owl:Class	
GO:0009557	biolink:NamedThing	antipodal cell differentiation	The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell.	got7fsn_ti														biological_process											owl:Class	
GO:1990068	biolink:NamedThing	seed dehydration	The seed development process whose outcome is the drying of a maturing seed.	got7fsn_ti							tb	2013-03-27T21:16:03Z						biological_process											owl:Class	
GO:0047133	biolink:NamedThing	dimethylamine dehydrogenase activity	Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine.	got7fsn_ti	DMADh activity|dimethylamine:electron-transferring flavoprotein oxidoreductase activity											EC:1.5.8.1|UM-BBD_reactionID:r1380|RHEA:10204|MetaCyc:1.5.8.1-RXN		molecular_function											owl:Class	
GO:0046665	biolink:NamedThing	amnioserosa maintenance	Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis.	got7fsn_ti														biological_process											owl:Class	
GO:0004377	biolink:NamedThing	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity	Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.	got7fsn_ti	guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity|GDP-mannose-oligosaccharide-lipid mannosyltransferase activity|GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity|GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity|oligosaccharide-lipid mannosyltransferase activity|glycolipid 2-alpha-mannosyltransferase activity											EC:2.4.1.131|RHEA:29523|MetaCyc:2.4.1.131-RXN		molecular_function											owl:Class	
GO:0047135	biolink:NamedThing	bis-gamma-glutamylcystine reductase activity	Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH.	got7fsn_ti	Bis-gamma-glutamylcystine reductase (NADPH)|bis-gamma-glutamylcystine reductase (NADPH) activity|NADPH:bis-gamma-glutamylcysteine oxidoreductase activity|gamma-glutamylcysteine:NADP+ oxidoreductase activity|NADPH2:bis-gamma-glutamylcysteine oxidoreductase activity|bis-g-glutamylcystine reductase (NADPH) activity											RHEA:11980|KEGG_REACTION:R02742|EC:1.8.1.13|MetaCyc:1.6.4.9-RXN		molecular_function											owl:Class	
GO:0010296	biolink:NamedThing	prenylcysteine methylesterase activity	Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+.	got7fsn_ti												MetaCyc:RXN-8409|RHEA:48520		molecular_function											owl:Class	
GO:0036502	biolink:NamedThing	Derlin-1-VIMP complex	A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome.	got7fsn_ti	Derlin-1/VIMP complex						bf	2015-05-14T11:40:45Z						cellular_component											owl:Class	
GO:0043968	biolink:NamedThing	histone H2A acetylation	The modification of histone H2A by the addition of an acetyl group.	got7fsn_ti														biological_process											owl:Class	
GO:0018121	biolink:NamedThing	NAD(P)-asparagine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine.	got7fsn_ti														molecular_function											owl:Class	
GO:0033761	biolink:NamedThing	mugineic-acid 3-dioxygenase activity	Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2.	got7fsn_ti	mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|IDS2											MetaCyc:RXN-7982|KEGG_REACTION:R07186|RHEA:14509|EC:1.14.11.25		molecular_function											owl:Class	
GO:0070871	biolink:NamedThing	cell wall organization involved in conjugation with cellular fusion	A process of cell wall organization that contributes to conjugation with cellular fusion.	got7fsn_ti	cell wall organisation involved in conjugation with cellular fusion						mah	2009-08-20T02:23:19Z						biological_process											owl:Class	
GO:0032349	biolink:NamedThing	positive regulation of aldosterone biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.	got7fsn_ti	up regulation of aldosterone biosynthetic process|activation of aldosterone biosynthetic process|up-regulation of aldosterone biosynthetic process|stimulation of aldosterone biosynthetic process|upregulation of aldosterone biosynthetic process													biological_process											owl:Class	
GO:0047958	biolink:NamedThing	glycine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate.	got7fsn_ti	glycine transaminase activity|L-glutamate:glyoxylate aminotransferase activity|glyoxylate-glutamic transaminase activity|glycine aminotransferase activity|glutamate-glyoxylate transaminase activity|glyoxylate-glutamate aminotransferase activity|glutamic-glyoxylic transaminase activity											RHEA:14089|MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN|EC:2.6.1.4		molecular_function											owl:Class	
GO:0016689	biolink:NamedThing	manganese peroxidase activity	Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O.	got7fsn_ti	Mn-dependent peroxidase activity|Mn-dependent (NADH-oxidizing) peroxidase activity|Mn(II):hydrogen-peroxide oxidoreductase activity|peroxidase-M2											RHEA:22776|EC:1.11.1.13|MetaCyc:MANGANESE-PEROXIDASE-RXN		molecular_function											owl:Class	
GO:0036019	biolink:NamedThing	endolysosome	An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place.	got7fsn_ti							bf	2011-10-13T02:35:13Z						cellular_component											owl:Class	
GO:1990423	biolink:NamedThing	RZZ complex	A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints.	got7fsn_ti	Rod-Zwilch-Zw10 complex				Example annotations for this term would be D. melanogaster mit(1)15 (Q9W4X9), rod and zwilch (Q9VA00).		jl	2014-07-23T11:16:42Z						cellular_component											owl:Class	
GO:0050025	biolink:NamedThing	L-glutamate oxidase activity	Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2.	got7fsn_ti	glutamate (acceptor) dehydrogenase activity|glutamic dehydrogenase (acceptor)|glutamic acid oxidase activity|L-glutamate:oxygen oxidoreductase (deaminating)|glutamate oxidase activity|L-glutamic acid oxidase activity											MetaCyc:L-GLUTAMATE-OXIDASE-RXN|RHEA:20728|EC:1.4.3.11		molecular_function											owl:Class	
GO:0097652	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class II	A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast.	got7fsn_ti	class II phosphatidylinositol 3-kinase complex|class II PI3K complex						pr	2014-09-16T13:14:17Z						cellular_component											owl:Class	
GO:0034771	biolink:NamedThing	histone H4-K20 monomethylation	The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone.	got7fsn_ti	histone H4 K20 monomethylation|histone lysine H4 K20 monomethylation													biological_process											owl:Class	
GO:0031761	biolink:NamedThing	fMet-Leu-Phe receptor binding	Binding to a fMet-Leu-Phe receptor.	got7fsn_ti	N-formyl peptide receptor binding|fMet-Leu-Phe receptor ligand													molecular_function											owl:Class	
GO:0018446	biolink:NamedThing	pinocarveol dehydrogenase activity	Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0717		molecular_function											owl:Class	
GO:0016084	biolink:NamedThing	myostimulatory hormone activity	The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.	got7fsn_ti														molecular_function											owl:Class	
GO:0030572	biolink:NamedThing	phosphatidyltransferase activity	Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group.	got7fsn_ti														molecular_function											owl:Class	
GO:0032137	biolink:NamedThing	guanine/thymine mispair binding	Binding to a double-stranded DNA region containing a G/T mispair.	got7fsn_ti	G/T mispair binding|T/G mispair binding|thymine/guanine mispair binding													molecular_function											owl:Class	
GO:0002172	biolink:NamedThing	high-affinity IgM receptor activity	Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	high affinity IgM receptor activity						hjd	2010-05-06T05:03:26Z						molecular_function											owl:Class	
GO:0001793	biolink:NamedThing	IgM receptor activity	Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0014810	biolink:NamedThing	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.	got7fsn_ti														biological_process											owl:Class	
GO:0014809	biolink:NamedThing	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.	got7fsn_ti														biological_process											owl:Class	
GO:0044209	biolink:NamedThing	AMP salvage	The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.	got7fsn_ti	AMP biosynthetic process via salvage pathway|adenosine monophosphate salvage						jl	2009-10-22T02:52:11Z						biological_process											owl:Class	
GO:0072732	biolink:NamedThing	cellular response to calcium ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions.	got7fsn_ti	cellular response to calcium starvation						mah	2012-07-06T02:42:26Z						biological_process											owl:Class	
GO:0010619	biolink:NamedThing	adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	got7fsn_ti	activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway|activation of adenylate cyclase activity by glucose involved in G-protein signaling|activation of adenylate cyclase activity by glucose-triggered G-protein signalling pathway|glucose-sensing PKA pathway													biological_process											owl:Class	
GO:0102155	biolink:NamedThing	S-sulfolactate dehydrogenase activity	Catalysis of the reaction: (S)-3-sulfonatolactate + NAD <=> 3-sulfonatopyruvate(2-) + NADH + H+.	got7fsn_ti												RHEA:28194|MetaCyc:RXN-11689|EC:1.1.1.310		molecular_function											owl:Class	
GO:0047846	biolink:NamedThing	deoxynucleotide 3'-phosphatase activity	Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate.	got7fsn_ti	3'-deoxynucleotidase activity|deoxyribonucleotide 3'-phosphohydrolase activity|3'-deoxyribonucleotidase activity											RHEA:10092|EC:3.1.3.34|MetaCyc:DEOXYNUCLEOTIDE-3-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0102741	biolink:NamedThing	paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity	Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine  <=> H+ + caffeine + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-7601|EC:2.1.1.160|RHEA:10280		molecular_function											owl:Class	
GO:0048211	biolink:NamedThing	Golgi vesicle docking	The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane.	got7fsn_ti	Golgi vesicle to membrane docking|dictyosome vesicle docking to target membrane|Golgi-derived vesicle docking|Golgi vesicle docking with target membrane													biological_process											owl:Class	
GO:0140504	biolink:NamedThing	microlipophagy	Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination.	got7fsn_ti	lipid droplet autophagy	https://github.com/geneontology/go-ontology/issues/19869					pg	2020-08-14T12:53:43Z						biological_process											owl:Class	
GO:0038107	biolink:NamedThing	nodal signaling pathway involved in determination of left/right asymmetry	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of an organism's body plan or part of an organism with respect to the left and right halves.	got7fsn_ti	nodal signalling pathway involved in determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter by nodal signaling pathway, involved in determination of left/right symmetry						bf	2012-02-29T10:18:59Z						biological_process											owl:Class	
GO:1900094	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry	Any regulation of transcription from RNA polymerase II promoter that is involved in determination of left/right symmetry.	got7fsn_ti	regulation of global transcription from Pol II promoter of determination of left/right asymmetry|global transcription regulation from Pol II promoter of determination of left/right symmetry|regulation of transcription from Pol II promoter of determination of left/right symmetry|regulation of transcription from Pol II promoter of determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter of determination of left/right symmetry|regulation of global transcription from Pol II promoter of determination of left/right symmetry|regulation of transcription from RNA polymerase II promoter of determination of left/right asymmetry|regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right symmetry|regulation of transcription from RNA polymerase II promoter, global of determination of left/right symmetry|regulation of transcription from RNA polymerase II promoter, global of determination of left/right asymmetry|regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right asymmetry|global transcription regulation from Pol II promoter of determination of left/right asymmetry						vk	2012-02-14T10:58:20Z						biological_process											owl:Class	
GO:0097377	biolink:NamedThing	spinal cord interneuron axon guidance	The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.	got7fsn_ti							pr	2012-10-01T10:19:42Z						biological_process											owl:Class	
GO:0099548	biolink:NamedThing	trans-synaptic signaling by nitric oxide	Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide.	got7fsn_ti														biological_process											owl:Class	
GO:1990383	biolink:NamedThing	cellular response to biotin starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin.	got7fsn_ti							al	2014-05-21T10:06:58Z						biological_process											owl:Class	
GO:0050040	biolink:NamedThing	lactate 2-monooxygenase activity	Catalysis of the reaction: (S)-lactate + O(2) = acetate + CO(2) + H(2)O.	got7fsn_ti	lactic oxygenase activity|L-lactate monooxygenase activity|lactate oxygenase activity|(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)|lactate monooxygenase activity|lactate oxidative decarboxylase activity|L-lactate-2-monooxygenase activity|lactic oxidase activity|lactate oxidase activity											EC:1.13.12.4|MetaCyc:LACTATE-2-MONOOXYGENASE-RXN|RHEA:16513|KEGG_REACTION:R00319		molecular_function											owl:Class	
GO:0061764	biolink:NamedThing	late endosome to lysosome transport via multivesicular body sorting pathway	The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.	got7fsn_ti							dph	2016-04-19T09:29:57Z						biological_process											owl:Class	
GO:0036211	biolink:NamedThing	protein modification process	The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).	got7fsn_ti	protein modification						bf	2012-04-26T01:47:12Z						biological_process											owl:Class	
GO:0042026	biolink:NamedThing	protein refolding	The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.	got7fsn_ti	heat shock protein activity													biological_process											owl:Class	
GO:0098967	biolink:NamedThing	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception.  This process includes tethering and docking steps that prepare vesicles for fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0036147	biolink:NamedThing	rumination	A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again.	got7fsn_ti	digestive rumination						bf	2012-03-13T04:35:19Z						biological_process											owl:Class	
GO:0035911	biolink:NamedThing	descending aorta morphogenesis	The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.	got7fsn_ti							bf	2011-06-24T11:19:24Z						biological_process											owl:Class	
GO:0002259	biolink:NamedThing	endothelial cell activation within high endothelial venule involved in immune response	A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	endothelial cell activation within high endothelial venule during immune response													biological_process											owl:Class	
GO:0002264	biolink:NamedThing	endothelial cell activation involved in immune response	A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	endothelial cell activation during immune response													biological_process											owl:Class	
GO:0010123	biolink:NamedThing	acetate catabolic process to butyrate, ethanol, acetone and butanol	The anaerobic chemical reactions and pathways resulting in the breakdown of acetate to form butyrate, ethanol, acetone and butanol.	got7fsn_ti	acetate fermentation to butyrate, ethanol, acetone and butanol											MetaCyc:CENTFERM-PWY		biological_process											owl:Class	
GO:0008465	biolink:NamedThing	glycerate dehydrogenase activity	Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+.	got7fsn_ti	hydroxypyruvate dehydrogenase activity											RHEA:17905|EC:1.1.1.29|MetaCyc:GLYCERATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0008776	biolink:NamedThing	acetate kinase activity	Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate.	got7fsn_ti	AckA|AK activity|acetate kinase (phosphorylating) activity|ATP:acetate phosphotransferase activity|acetic kinase activity|acetokinase activity											RHEA:11352|EC:2.7.2.1|MetaCyc:ACETATEKIN-RXN		molecular_function											owl:Class	
GO:0006881	biolink:NamedThing	extracellular sequestering of iron ion	The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system.	got7fsn_ti	extracellular retention of iron ion|extracellular iron ion sequestration|extracellular sequestration of iron ion|extracellular iron ion retention|extracellular iron ion storage|extracellular iron ion sequestering|extracellular storage of iron ion													biological_process											owl:Class	
GO:0097577	biolink:NamedThing	sequestering of iron ion	The process of binding or confining iron ions such that they are separated from other components of a biological system.	got7fsn_ti	retention of iron ion|iron ion retention|storage of iron ion|sequestration of iron ion|iron ion sequestration|iron ion storage|iron ion sequestering						pr	2014-02-28T11:10:53Z						biological_process											owl:Class	
GO:0070464	biolink:NamedThing	alphav-beta3 integrin-collagen alpha3(VI) complex	A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.	got7fsn_ti														cellular_component											owl:Class	
GO:0098511	biolink:NamedThing	sensory perception of low humidity	The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti							dos	2013-09-25T14:02:02Z						biological_process											owl:Class	
GO:0061529	biolink:NamedThing	epinephrine secretion, neurotransmission	The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.	got7fsn_ti	adrenaline secretion, neurotransmission						dph	2013-06-21T15:47:22Z						biological_process											owl:Class	
GO:0032237	biolink:NamedThing	activation of store-operated calcium channel activity	A process that initiates the activity of an inactive store-operated calcium channel.	got7fsn_ti														biological_process											owl:Class	
GO:1901341	biolink:NamedThing	positive regulation of store-operated calcium channel activity	Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity.	got7fsn_ti	up-regulation of store-operated calcium channel activity|activation of store-operated calcium channel activity|up regulation of store-operated calcium channel activity|upregulation of store-operated calcium channel activity						pr	2012-09-03T14:24:38Z						biological_process											owl:Class	
GO:0072716	biolink:NamedThing	response to actinomycin D	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.	got7fsn_ti							mah	2012-04-26T02:06:40Z						biological_process											owl:Class	
GO:0033417	biolink:NamedThing	CUU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CUU codon.	got7fsn_ti	leucine tRNA|CTT codon-amino acid adaptor activity				Note that in the standard genetic code, CTT codes for leucine.									molecular_function											owl:Class	
GO:0042407	biolink:NamedThing	cristae formation	The assembly of cristae, the inwards folds of the inner mitochondrial membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0090686	biolink:NamedThing	glycine betaine-activated nonselective monovalent cation channel activity	Enables the transmembrane transfer of a monovalent cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts.	got7fsn_ti							tb	2016-07-20T16:29:01Z						molecular_function											owl:Class	
GO:0052655	biolink:NamedThing	L-valine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid.	got7fsn_ti	L-valine aminotransferase activity											EC:2.6.1.42|MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN|RHEA:24813|KEGG_REACTION:R01214		molecular_function											owl:Class	
GO:0004084	biolink:NamedThing	branched-chain-amino-acid transaminase activity	Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.	got7fsn_ti	branched-chain amino acid aminotransferase activity|glutamate-branched-chain amino acid transaminase activity|branched-chain-amino-acid:2-oxoglutarate aminotransferase activity|branched-chain amino acid-glutamate transaminase activity|branched-chain aminotransferase activity|transaminase B activity|L-branched chain amino acid aminotransferase activity											Reactome:R-HSA-70724|EC:2.6.1.42|Reactome:R-HSA-508179|Reactome:R-HSA-508189|Reactome:R-HSA-70723		molecular_function											owl:Class	
GO:0071722	biolink:NamedThing	detoxification of arsenic-containing substance	Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds.	got7fsn_ti	detoxification of arsenic						mah	2010-03-17T01:35:56Z						biological_process											owl:Class	
GO:0015616	biolink:NamedThing	DNA translocase activity	Generation of movement along a single- or double-stranded DNA molecule, driven by ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21612			Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane.									molecular_function											owl:Class	
GO:0005595	biolink:NamedThing	collagen type XII trimer	A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.	got7fsn_ti														cellular_component											owl:Class	
GO:0018526	biolink:NamedThing	2-aminobenzoyl-CoA reductase activity	Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0342		molecular_function											owl:Class	
GO:0043798	biolink:NamedThing	glycerate 2-kinase activity	Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP.	got7fsn_ti	glycerate kinase|D-glycerate 2-kinase activity											EC:2.7.1.165|MetaCyc:GKI-RXN|RHEA:27377		molecular_function											owl:Class	
GO:0047902	biolink:NamedThing	formylaspartate deformylase activity	Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.	got7fsn_ti	N-formyl-L-aspartate amidohydrolase activity|formylaspartic formylase (formylase I, formylase II)											MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN|RHEA:22040|EC:3.5.1.8		molecular_function											owl:Class	
GO:0047677	biolink:NamedThing	arachidonate 8(R)-lipoxygenase activity	Catalysis of the reaction: arachidonate + O(2) = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.	got7fsn_ti	arachidonate 8-lipoxygenase activity|arachidonate:oxygen 8-oxidoreductase activity|8(R)-lipoxygenase activity|8-lipoxygenase activity				This activity produces the R-enantiomer of HPETE, 8(R)-HPETE. For the reaction producing the S-enantiomer, see GO:0036403.							MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN|EC:1.13.11.40|RHEA:14985|KEGG_REACTION:R01594		molecular_function											owl:Class	
GO:0071432	biolink:NamedThing	peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion	The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion.	got7fsn_ti	peptide mating pheromone formation involved in conjugation with cellular fusion|alpha-factor maturation|peptide mating pheromone processing involved in conjugation with cellular fusion|a-factor processing (proteolytic)|mating-type peptide pheromone maturation involved in conjugation with cellular fusion						mah	2009-12-16T10:46:50Z						biological_process											owl:Class	
GO:0098885	biolink:NamedThing	modification of postsynaptic actin cytoskeleton	Any process that modifies the structure of a postsynaptic actin cytoskeleton.	got7fsn_ti	postsynaptic actin cytoskeleton remodelling				This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones.									biological_process											owl:Class	
GO:0099010	biolink:NamedThing	modification of postsynaptic structure	Any process that modifies the structure of a postsynapse.	got7fsn_ti	synapse remodelling				This class does not cover assembly or disassembly of postsynapses, only the modification/remodelling of existing ones.									biological_process											owl:Class	
GO:0004018	biolink:NamedThing	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.	got7fsn_ti	succino AMP-lyase activity|6-N-(1,2-dicarboxyethyl)AMP AMP-lyase activity|adenylosuccinate lyase activity|adenylosuccinase activity|N6-(1,2-dicarboxyethyl)AMP AMP-lyase activity											Reactome:R-HSA-73800|RHEA:16853|EC:4.3.2.2|KEGG_REACTION:R01083|Reactome:R-HSA-73828|MetaCyc:AMPSYN-RXN		molecular_function											owl:Class	
GO:0050411	biolink:NamedThing	agaritine gamma-glutamyltransferase activity	Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor.	got7fsn_ti	(gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity|(gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity|agaritine g-glutamyltransferase activity											MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.9		molecular_function											owl:Class	
GO:0002403	biolink:NamedThing	T cell tolerance induction in mucosal-associated lymphoid tissue	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells.	got7fsn_ti	T cell tolerance induction in MALT													biological_process											owl:Class	
GO:0003972	biolink:NamedThing	RNA ligase (ATP) activity	Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m).	got7fsn_ti	polyribonucleotide synthase (ATP) activity|ribonucleic ligase activity|polyribonucleotide ligase activity|poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming)											MetaCyc:RNA-LIGASE-ATP-RXN|Reactome:R-HSA-5696816|EC:6.5.1.3		molecular_function											owl:Class	
GO:0102855	biolink:NamedThing	1-18:1-2-18:2-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												RHEA:46332|EC:1.14.19.22|MetaCyc:RXN-8322		molecular_function											owl:Class	
GO:0018285	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide	The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl diiron disulphide											RESID:AA0137		biological_process											owl:Class	
GO:0046651	biolink:NamedThing	lymphocyte proliferation	The expansion of a lymphocyte population by cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0060200	biolink:NamedThing	clathrin-sculpted acetylcholine transport vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine.	got7fsn_ti	clathrin sculpted acetylcholine transport vesicle|clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle													cellular_component											owl:Class	
GO:0039529	biolink:NamedThing	RIG-I signaling pathway	Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	got7fsn_ti	retinoic acid inducible gene I signaling pathway|DDX58 signaling pathway|RIG-I signalling pathway				The apoptosis effect triggered by the RIG-I signaling pathway is inconclusive and may represent an in-vitro phenomenon. Therefore, in GO the term 'RIG-I signaling pathway ; GO:0039529' is positioned under 'regulation of cytokine production' as this is its primary effect.		bf	2011-12-20T03:11:06Z						biological_process											owl:Class	
GO:0098620	biolink:NamedThing	seryl-selenocysteinyl-tRNA kinase activity	Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP.	got7fsn_ti												Reactome:R-HSA-2408507		molecular_function											owl:Class	
GO:0042013	biolink:NamedThing	interleukin-19 binding	Binding to interleukin-19.	got7fsn_ti	IL-19 binding													molecular_function											owl:Class	
GO:0060540	biolink:NamedThing	diaphragm morphogenesis	The process in which the anatomical structures of the diaphragm are generated and organized.	got7fsn_ti							dph	2009-04-10T08:47:51Z						biological_process											owl:Class	
GO:0070302	biolink:NamedThing	regulation of stress-activated protein kinase signaling cascade	Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.	got7fsn_ti	regulation of stress-activated protein kinase signalling pathway|regulation of stress-activated protein kinase signaling pathway|regulation of SAPK signaling pathway													biological_process											owl:Class	
GO:0070102	biolink:NamedThing	interleukin-6-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-6-mediated signaling pathway|interleukin-6-mediated signalling pathway													biological_process											owl:Class	
GO:0033837	biolink:NamedThing	anthocyanin 3'-O-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside.	got7fsn_ti	UDP-glucose:anthocyanin 3'-O-glucosyltransferase activity|UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase activity|3'GT											MetaCyc:2.4.1.238-RXN|EC:2.4.1.238|RHEA:35627		molecular_function											owl:Class	
GO:0042466	biolink:NamedThing	chemokinesis	A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis).	got7fsn_ti												Wikipedia:Chemokinesis		biological_process											owl:Class	
GO:0003242	biolink:NamedThing	cardiac chamber ballooning	The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping.	got7fsn_ti							dph	2009-10-13T11:30:30Z						biological_process											owl:Class	
GO:0072551	biolink:NamedThing	diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity	Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O.	got7fsn_ti							mah	2011-01-25T03:04:16Z						molecular_function											owl:Class	
GO:1990302	biolink:NamedThing	Bre1-Rad6 ubiquitin ligase complex	A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis.	got7fsn_ti	Bre1-Rad6 complex				This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).		bhm	2014-02-28T16:50:34Z						cellular_component											owl:Class	
GO:0032184	biolink:NamedThing	SUMO polymer binding	Binding to a polymer of the small ubiquitin-like protein SUMO.	got7fsn_ti	Smt3 polymer binding													molecular_function											owl:Class	
GO:0032183	biolink:NamedThing	SUMO binding	Binding to the small ubiquitin-like protein SUMO.	got7fsn_ti	Smt3 monomer binding|Smt3 binding													molecular_function											owl:Class	
GO:0031093	biolink:NamedThing	platelet alpha granule lumen	The volume enclosed by the membrane of the platelet alpha granule.	got7fsn_ti	platelet alpha-granule lumen													cellular_component											owl:Class	
GO:0106259	biolink:NamedThing	cell-to-cell migration in host	The directional movement of a symbiont from one host cell to another.	got7fsn_ti							hjd	2020-05-01T14:09:35Z						biological_process											owl:Class	
GO:0052732	biolink:NamedThing	phosphoethanolamine phosphatase activity	Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate.	got7fsn_ti	PHOSPHO1|phosphoethanolamine phosphohydrolase activity|3X11A						ai	2011-08-16T04:09:19Z				EC:3.1.3.75|Reactome:R-HSA-1483096|MetaCyc:RXN-7948|RHEA:16089|KEGG_REACTION:R06870		molecular_function											owl:Class	
GO:0035501	biolink:NamedThing	MH1 domain binding	Binding to a MH1 (MAD homology 1) protein domain. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.	got7fsn_ti	MAD homology 1 domain binding						bf	2010-04-29T03:17:27Z						molecular_function											owl:Class	
GO:1990031	biolink:NamedThing	pinceau fiber	Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment.	got7fsn_ti							pr	2013-02-07T12:56:50Z				NIF_Subcellular:sao109906988		cellular_component											owl:Class	
GO:0050792	biolink:NamedThing	regulation of viral process	Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.	got7fsn_ti	regulation of viral reproduction|regulation of viral process													biological_process											owl:Class	
GO:0050184	biolink:NamedThing	phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + H(+) + NADH.	got7fsn_ti	linoleate synthase activity|oleoyl-CoA desaturase activity|1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ delta12-oxidoreductase activity|oleoylphosphatidylcholine desaturase activity|acyl-lipid omega-6 desaturase (cytochrome b5)|oleate desaturase activity											KEGG_REACTION:R03475|EC:1.14.19.22|RHEA:12564|MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN		molecular_function											owl:Class	
GO:0050096	biolink:NamedThing	methylaspartate ammonia-lyase activity	Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH(4)(+).	got7fsn_ti	beta-methylaspartase activity|3-methylaspartase activity|L-threo-3-methylaspartate ammonia-lyase activity|L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)											KEGG_REACTION:R03696|MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN|RHEA:12829|EC:4.3.1.2		molecular_function											owl:Class	
GO:0043429	biolink:NamedThing	2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	got7fsn_ti	2-nonaprenyl-6-methoxy-1,4-benzoquinone methylase activity				Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.									molecular_function											owl:Class	
GO:0008949	biolink:NamedThing	oxalyl-CoA decarboxylase activity	Catalysis of the reaction: H(+) + oxalyl-CoA = CO(2) + formyl-CoA.	got7fsn_ti	oxalyl coenzyme A decarboxylase activity|oxalyl-CoA carboxy-lyase (formyl-CoA-forming)|oxalyl-CoA carboxy-lyase activity											KEGG_REACTION:R01908|EC:4.1.1.8|MetaCyc:OXALYL-COA-DECARBOXYLASE-RXN|RHEA:19333		molecular_function											owl:Class	
GO:0034831	biolink:NamedThing	(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity	Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1176		molecular_function											owl:Class	
GO:0046716	biolink:NamedThing	muscle cell cellular homeostasis	The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.	got7fsn_ti	muscle homeostasis|muscle fiber maintenance													biological_process											owl:Class	
GO:0044191	biolink:NamedThing	host cell mitochondrial membrane	Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope.	got7fsn_ti							jl	2009-10-15T04:14:35Z						cellular_component											owl:Class	
GO:0071215	biolink:NamedThing	cellular response to abscisic acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.	got7fsn_ti							mah	2009-12-03T01:04:18Z						biological_process											owl:Class	
GO:0009737	biolink:NamedThing	response to abscisic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.	got7fsn_ti	response to abscisic acid stimulus													biological_process											owl:Class	
GO:0102161	biolink:NamedThing	copal-8-ol diphosphate synthase activity	Catalysis of the reaction: copal-8-ol diphosphate <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O.	got7fsn_ti												EC:4.2.1.133|MetaCyc:RXN-11772|RHEA:32703		molecular_function											owl:Class	
GO:1990508	biolink:NamedThing	CKM complex	Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8.	got7fsn_ti	SRB8/9/10/11 complex|CDK8 kinase module|SRB8-SRB11 complex				An example of this is SSN2 in Saccharomyces cerevisiae (P38931) in PMID:12200444 (inferred from physical interaction).		bhm	2014-10-02T10:05:58Z						cellular_component											owl:Class	
GO:0035383	biolink:NamedThing	thioester metabolic process	The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.	got7fsn_ti	thioester metabolism						bf	2010-03-18T01:48:12Z						biological_process											owl:Class	
GO:0009730	biolink:NamedThing	detection of carbohydrate stimulus	The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of carbohydrate stimulus													biological_process											owl:Class	
GO:0035299	biolink:NamedThing	inositol pentakisphosphate 2-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+).	got7fsn_ti	inositol 1,3,4,5,6-pentakisphosphate 2-kinase activity|inositol-pentakisphosphate 2-kinase activity|inositol hexakisphosphate synthase|Ipk1p|inositol polyphosphate kinase activity|Gsl1p|ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase activity|Ins(1,3,4,5,6)P5 2-kinase activity|IP5 2-kinase activity											Reactome:R-HSA-1855176|RHEA:20313|MetaCyc:RXN-7163|Reactome:R-HSA-1855179|KEGG_REACTION:R05202|EC:2.7.1.158		molecular_function											owl:Class	
GO:0051108	biolink:NamedThing	carnitine-CoA ligase activity	Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.	got7fsn_ti	carnitine synthetase activity|crotonobetaine/carnitine-CoA ligase activity											RHEA:30543|MetaCyc:DCARNCOALIG-RXN		molecular_function											owl:Class	
GO:0004738	biolink:NamedThing	pyruvate dehydrogenase activity	Catalysis of the oxidative decarboxylation of pyruvate.	got7fsn_ti	pyruvic acid dehydrogenase activity|pyruvic dehydrogenase activity											Reactome:R-HSA-71397|MetaCyc:PYRUVOXID-RXN|MetaCyc:RXN0-1134		molecular_function											owl:Class	
GO:0003941	biolink:NamedThing	L-serine ammonia-lyase activity	Catalysis of the reaction: L-serine = pyruvate + NH3.	got7fsn_ti	L-serine dehydratase activity|L-serine ammonia-lyase (pyruvate-forming) activity|L-hydroxyaminoacid dehydratase activity|L-serine dehydration activity|serine deaminase activity|L-serine deaminase activity|L-serine hydro-lyase (deaminating) activity				Note that this function was formerly EC:4.3.1.13.							MetaCyc:4.3.1.17-RXN|RHEA:19169|EC:4.3.1.17		molecular_function											owl:Class	
GO:0035657	biolink:NamedThing	eRF1 methyltransferase complex	A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.	got7fsn_ti	eRF1 MTase complex						bf	2011-01-28T11:29:40Z						cellular_component											owl:Class	
GO:0035552	biolink:NamedThing	oxidative single-stranded DNA demethylation	Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.	got7fsn_ti	oxidative ssDNA demethylation						bf	2010-05-14T11:03:55Z						biological_process											owl:Class	
GO:0048225	biolink:NamedThing	suberin network	An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier.	got7fsn_ti														cellular_component											owl:Class	
GO:0034866	biolink:NamedThing	2,4,4-trimethylpentanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1276		molecular_function											owl:Class	
GO:0044316	biolink:NamedThing	cone cell pedicle	A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL).	got7fsn_ti	cone pedicle						jl	2010-07-14T01:30:02Z						cellular_component											owl:Class	
GO:0052608	biolink:NamedThing	echinenone 3-hydroxylase activity	Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O.	got7fsn_ti	beta-carotene hydroxylase activity|carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity											MetaCyc:RXN-8214		molecular_function											owl:Class	
GO:0034221	biolink:NamedThing	fungal-type cell wall chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells.	got7fsn_ti	fungal-type cell wall chitin formation|fungal-type cell wall chitin biosynthesis|fungal-type cell wall chitin synthesis|fungal-type cell wall chitin anabolism													biological_process											owl:Class	
GO:0033995	biolink:NamedThing	anhydrosialidase activity	Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.	got7fsn_ti	anhydroneuraminidase activity|glycoconjugate sialyl-lyase (2,7-cyclizing) activity|sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing) activity|sialidase L activity											EC:4.2.2.15|MetaCyc:4.2.2.15-RXN		molecular_function											owl:Class	
GO:0060182	biolink:NamedThing	apelin receptor activity	Combining with the peptide apelin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0046415	biolink:NamedThing	urate metabolic process	The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.	got7fsn_ti	urate metabolism													biological_process											owl:Class	
GO:0035966	biolink:NamedThing	response to topologically incorrect protein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.	got7fsn_ti	response to misfolded or unfolded protein						bf	2011-08-03T11:43:12Z						biological_process											owl:Class	
GO:0050493	biolink:NamedThing	GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GPI anchor anabolism via N-threonyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-threonyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-threonyl-glycosylphosphatidylinositolethanolamine											RESID:AA0164		biological_process											owl:Class	
GO:0031233	biolink:NamedThing	intrinsic component of external side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor.	got7fsn_ti	intrinsic to external leaflet of plasma membrane|intrinsic to external side of plasma membrane													cellular_component											owl:Class	
GO:0031226	biolink:NamedThing	intrinsic component of plasma membrane	The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to plasma membrane													cellular_component											owl:Class	
GO:0016633	biolink:NamedThing	galactonolactone dehydrogenase activity	Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.	got7fsn_ti	L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase activity|L-galactono-1,4-lactone dehydrogenase activity|GLDase activity|L-galactono-gamma-lactone:ferricytochrome-c oxidoreductase activity|L-galactono-gamma-lactone dehydrogenase activity|GLDHase activity|L-galactonolactone dehydrogenase activity											EC:1.3.2.3|MetaCyc:GALACTONOLACTONE-DEHYDROGENASE-RXN|RHEA:32367		molecular_function											owl:Class	
GO:0030107	biolink:NamedThing	HLA-A specific inhibitory MHC class I receptor activity	Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.	got7fsn_ti														molecular_function											owl:Class	
GO:0061501	biolink:NamedThing	2',3'-cyclic GMP-AMP synthase activity	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).	got7fsn_ti	cyclic 2',3' GAMP synthase activity|cyclic-GMP-AMP synthase activity|2',3' cyclic-GMP-AMP synthase activity|2',3' cyclic GMP-AMP synthase activity	https://github.com/geneontology/go-ontology/issues/21980					dph	2013-01-04T07:17:57Z				EC:2.7.7.86|Reactome:R-HSA-3244614|RHEA:42064		molecular_function											owl:Class	
GO:0150089	biolink:NamedThing	multiple spine synapse organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines.	got7fsn_ti	multi-synaptic organization|multisynapse organisation|multisynaptic organisation|multisynaptic organization|multi-synapse organisation|multi-synaptic organisation|multi-synapse organization|multiple spine synapse organisation|multisynapse organization						bc	2018-08-08T14:54:50Z						biological_process											owl:Class	
GO:0044853	biolink:NamedThing	plasma membrane raft	A membrane raft that is part of the plasma membrane.	got7fsn_ti							jl	2014-07-23T15:55:23Z						cellular_component											owl:Class	
GO:0017056	biolink:NamedThing	structural constituent of nuclear pore	The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules.	got7fsn_ti	nucleocytoplasmic transporter activity|nuclear pore activity				Note that this term is meant to be used for nuclear pore proteins. For importins and exportins, consider 'nuclear import signal receptor activity' or 'nuclear export signal receptor activity', respectively.		tb	2015-06-29T08:59:16Z			GO:0005487	Reactome:R-HSA-1176059|Reactome:R-HSA-6783483|Reactome:R-HSA-5252041|Reactome:R-HSA-5661474|Reactome:R-HSA-170796|Reactome:R-HSA-5578744|Reactome:R-HSA-192627|Reactome:R-HSA-192925		molecular_function											owl:Class	
GO:0036031	biolink:NamedThing	recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex	The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript.	got7fsn_ti	capping enzyme targeting to RNA polymerase II|recruitment of guanylyltransferase to RNA polymerase II holoenzyme complex						bf	2011-10-24T10:56:46Z						biological_process											owl:Class	
GO:0017083	biolink:NamedThing	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-D-glucosaminyl-R.	got7fsn_ti	GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase activity|lewis-negative alpha-3-fucosyltransferase activity|galactoside 3-L-fucosyltransferase activity|guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase activity|GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity|GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity|Lewis-negative alpha-3-fucosyltransferase activity|guanosine diphosphofucose-glucoside alpha1->3-fucosyltransferase activity|plasma alpha-3-fucosyltransferase activity|galactoside 3-fucosyltransferase activity											RHEA:14257|EC:2.4.1.152|MetaCyc:GALACTOSIDE-3-FUCOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0019486	biolink:NamedThing	beta-alanine catabolic process to mevalonate semialdehyde, by transamination	The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination.	got7fsn_ti	beta-alanine breakdown to mevalonate semialdehyde, by transamination|beta-alanine degradation to mevalonate semialdehyde, by transamination											MetaCyc:BETA-ALA-DEGRADATION-I-PWY		biological_process											owl:Class	
GO:0019484	biolink:NamedThing	beta-alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.	got7fsn_ti	beta-alanine degradation|beta-alanine catabolism|beta-alanine breakdown													biological_process											owl:Class	
GO:0003153	biolink:NamedThing	closure of embryonic heart tube	Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold.	got7fsn_ti							tb	2009-09-23T10:14:54Z						biological_process											owl:Class	
GO:0036400	biolink:NamedThing	short neuropeptide F receptor activity	Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide.	got7fsn_ti	sNPF receptor activity				Despite their naming, neuropeptide F (NPF) and short neuropeptide F (sNPF) are not closely related.		bf	2013-07-18T14:46:40Z						molecular_function											owl:Class	
GO:0032263	biolink:NamedThing	GMP salvage	Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0006177	biolink:NamedThing	GMP biosynthetic process	The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.	got7fsn_ti	GMP biosynthesis|GMP anabolism|GMP formation|GMP synthesis													biological_process											owl:Class	
GO:0008670	biolink:NamedThing	2,4-dienoyl-CoA reductase (NADPH) activity	Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+.	got7fsn_ti	4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|4-enoyl-CoA reductase activity|4-enoyl-CoA reductase (NADPH2)|4-enoyl-CoA reductase (NADPH) activity|trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity											EC:1.3.1.34|RHEA:12136|MetaCyc:DIENOYLCOAREDUCT-RXN		molecular_function											owl:Class	
GO:0010862	biolink:NamedThing	positive regulation of pathway-restricted SMAD protein phosphorylation	Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	got7fsn_ti														biological_process											owl:Class	
GO:0090100	biolink:NamedThing	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.	got7fsn_ti	positive regulation of transmembrane receptor protein serine/threonine kinase signalling pathway						tb	2009-11-13T10:55:53Z						biological_process											owl:Class	
GO:0042209	biolink:NamedThing	orcinol catabolic process	The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.	got7fsn_ti	orcin catabolic process|orcin catabolism|orcinol catabolism|orcinol breakdown|orcinol degradation											UM-BBD_pathwayID:orc		biological_process											owl:Class	
GO:0021708	biolink:NamedThing	Lugaro cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0071972	biolink:NamedThing	peptidoglycan L,D-transpeptidase activity	Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.	got7fsn_ti							mah	2010-10-18T04:36:19Z				MetaCyc:RXN-11349		molecular_function											owl:Class	
GO:0035399	biolink:NamedThing	helper T cell enhancement of B cell mediated immune response	Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.	got7fsn_ti	helper T cell enhancement of B cell mediated immunity|provision of T cell help to B cell						bf	2010-03-23T10:41:46Z						biological_process											owl:Class	
GO:0002714	biolink:NamedThing	positive regulation of B cell mediated immunity	Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.	got7fsn_ti	activation of B cell mediated immunity|positive regulation of B-cell mediated immunity|up regulation of B cell mediated immunity|positive regulation of B-lymphocyte mediated immunity|positive regulation of B lymphocyte mediated immunity|up-regulation of B cell mediated immunity|upregulation of B cell mediated immunity|stimulation of B cell mediated immunity													biological_process											owl:Class	
GO:0009743	biolink:NamedThing	response to carbohydrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.	got7fsn_ti	response to carbohydrate stimulus													biological_process											owl:Class	
GO:0060272	biolink:NamedThing	embryonic skeletal joint morphogenesis	The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.	got7fsn_ti														biological_process											owl:Class	
GO:0035664	biolink:NamedThing	TIRAP-dependent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	got7fsn_ti	MAL-dependent toll-like receptor signaling pathway|TIRAP-dependent toll-like receptor signalling pathway|TIRAP-dependent TLR signaling pathway|MyD88 adapter-like dependent toll-like receptor signaling pathway						bf	2011-02-01T02:31:37Z						biological_process											owl:Class	
GO:0038098	biolink:NamedThing	sequestering of BMP from receptor via BMP binding	Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor.	got7fsn_ti	extracellular sequestering of BMP|extracellular sequestering of bone morphogenetic protein						bf	2012-02-22T11:28:54Z						biological_process											owl:Class	
GO:0047201	biolink:NamedThing	beta-glucogallin O-galloyltransferase activity	Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose.	got7fsn_ti	1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase activity											KEGG_REACTION:R00049|MetaCyc:2.3.1.90-RXN|EC:2.3.1.90|RHEA:11416		molecular_function											owl:Class	
GO:0046969	biolink:NamedThing	NAD-dependent histone deacetylase activity (H3-K9 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.	got7fsn_ti												Reactome:R-HSA-9604829		molecular_function											owl:Class	
GO:0000083	biolink:NamedThing	regulation of transcription involved in G1/S transition of mitotic cell cycle	Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0002276	biolink:NamedThing	basophil activation involved in immune response	A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	basophil activation during immune response													biological_process											owl:Class	
GO:0034954	biolink:NamedThing	diphenyl ether 2,3-dioxygenase activity	Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether.	got7fsn_ti												UM-BBD_reactionID:r1450|EC:1.14.12.-		molecular_function											owl:Class	
GO:0090153	biolink:NamedThing	regulation of sphingolipid biosynthetic process	Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	got7fsn_ti							tb	2009-12-08T03:25:49Z						biological_process											owl:Class	
GO:0036138	biolink:NamedThing	peptidyl-histidine hydroxylation	The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine.	got7fsn_ti							bf	2012-03-07T09:25:25Z						biological_process											owl:Class	
GO:0003050	biolink:NamedThing	regulation of systemic arterial blood pressure by atrial natriuretic peptide	The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide.	got7fsn_ti	blood pressure regulation by ANP|blood pressure regulation by atrial natriuretic peptide													biological_process											owl:Class	
GO:0015066	biolink:NamedThing	alpha-amylase inhibitor activity	Binds to and stops, prevents or reduces the activity of alpha-amylase.	got7fsn_ti														molecular_function											owl:Class	
GO:0050598	biolink:NamedThing	taxane 13-alpha-hydroxylase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol.	got7fsn_ti	taxane 13alpha-hydroxylase activity|taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating)|taxane 13a-hydroxylase activity											EC:1.14.14.106|KEGG_REACTION:R06308|MetaCyc:1.14.13.77-RXN|RHEA:18949		molecular_function											owl:Class	
GO:0000701	biolink:NamedThing	purine-specific mismatch base pair DNA N-glycosylase activity	Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.	got7fsn_ti	A/G-specific adenine DNA glycosylase activity											EC:3.2.2.31		molecular_function											owl:Class	
GO:0043708	biolink:NamedThing	cell adhesion involved in biofilm formation	The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.	got7fsn_ti	cell adhesion during biofilm formation													biological_process											owl:Class	
GO:0008210	biolink:NamedThing	estrogen metabolic process	The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.	got7fsn_ti	oestrogen metabolic process|oestrogen metabolism|estrogen metabolism													biological_process											owl:Class	
GO:0047483	biolink:NamedThing	imidazoleacetate-phosphoribosyldiphosphate ligase activity	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(2)O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H(+) + phosphate.	got7fsn_ti	5-phosphoribosylimidazoleacetate synthetase activity|imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and diphosphate-forming)											MetaCyc:6.3.4.8-RXN|KEGG_REACTION:R04068|RHEA:16485|EC:6.3.4.8		molecular_function											owl:Class	
GO:0102460	biolink:NamedThing	kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP.	got7fsn_ti												MetaCyc:RXN-14008		molecular_function											owl:Class	
GO:0047786	biolink:NamedThing	cortisone alpha-reductase activity	Catalysis of the reaction: 4,5alpha-dihydrocortisone + NADP(+) = cortisone + H(+) + NADPH.	got7fsn_ti	microsomal steroid reductase (5alpha)|4,5alpha-dihydrocortisone:NADP+ delta4-oxidoreductase activity|delta4-3-oxosteroid-5alpha-reductase|delta4-3-ketosteroid reductase (5alpha)|cortisone a-reductase activity|NADPH:Delta4-3-oxosteroid-5alpha-oxidoreductase activity|delta4-5alpha-reductase activity|cortisone delta4-5alpha-reductase activity											KEGG_REACTION:R02892|RHEA:17981|MetaCyc:CORTISONE-ALPHA-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0042712	biolink:NamedThing	paternal behavior	Male behaviors associated with the care and rearing offspring.	got7fsn_ti	paternal behaviour													biological_process											owl:Class	
GO:0023035	biolink:NamedThing	CD40 signaling pathway	A series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CD40 signalling pathway							2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0044595	biolink:NamedThing	decaprenyldihydroxybenzoate methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate.	got7fsn_ti							jl	2012-04-26T04:52:05Z				Reactome:R-HSA-2162193|MetaCyc:RXN-9282|RHEA:44492		molecular_function											owl:Class	
GO:0102876	biolink:NamedThing	psoralen synthase activity	Catalysis of the reaction: (+)-marmesin + NADPH + H+ + O2 <=> psoralen + NADP + acetone + 2 H2O.	got7fsn_ti												RHEA:19281|EC:1.14.14.141|MetaCyc:RXN-8386		molecular_function											owl:Class	
GO:0042781	biolink:NamedThing	3'-tRNA processing endoribonuclease activity	Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.	got7fsn_ti	3 tRNase activity|tRNA 3' endonuclease activity|3' tRNA processing endoribonuclease activity|ribonuclease Z activity|tRNA 3 endonuclease activity|tRNAse Z|3' tRNase activity|RNase Z activity	https://github.com/geneontology/go-ontology/issues/21383										MetaCyc:3.1.26.11-RXN|EC:3.1.26.11		molecular_function											owl:Class	
GO:0010247	biolink:NamedThing	detection of phosphate ion	The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	phosphate ion detection|phosphate ion perception|phosphate ion sensing													biological_process											owl:Class	
GO:0099045	biolink:NamedThing	viral extrusion	The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable.  Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded.	got7fsn_ti												VZ:3951		biological_process											owl:Class	
GO:0004354	biolink:NamedThing	glutamate dehydrogenase (NADP+) activity	Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.	got7fsn_ti	dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))|L-glutamic acid dehydrogenase activity|glutamic acid dehydrogenase|NAD(P)-glutamate dehydrogenase activity|L-glutamate dehydrogenase|L-glutamate:NADP+ oxidoreductase (deaminating)|glutamic dehydrogenase activity|NAD(P)H-dependent glutamate dehydrogenase activity											MetaCyc:GLUTSYNIII-PWY|EC:1.4.1.4|RHEA:11612|MetaCyc:GLUTDEHYD-RXN		molecular_function											owl:Class	
GO:0004353	biolink:NamedThing	glutamate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+.	got7fsn_ti	glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamic dehydrogenase activity|glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)|L-glutamate:NAD(P)+ oxidoreductase (deaminating)				Note that this term has a MetaCyc pathway reference as the pathway only has a single step.							Reactome:R-HSA-70600|Reactome:R-HSA-70589|EC:1.4.1.3|MetaCyc:GLUTAMATE-DEHYDROGENASE-NADP+-RXN|MetaCyc:GLUTAMATE-SYN2-PWY		molecular_function											owl:Class	
GO:1990313	biolink:NamedThing	type-III cohesin domain binding	Binding to a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain.	got7fsn_ti							tt	2014-03-07T04:58:07Z						molecular_function											owl:Class	
GO:1990763	biolink:NamedThing	arrestin family protein binding	Binding to a member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors.	got7fsn_ti							sl	2015-06-09T23:29:42Z						molecular_function											owl:Class	
GO:0018548	biolink:NamedThing	pentaerythritol trinitrate reductase activity	Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate.	got7fsn_ti	xenobiotic reductase activity											UM-BBD_reactionID:r0025|EC:1.6.99.1		molecular_function											owl:Class	
GO:0018501	biolink:NamedThing	cis-chlorobenzene dihydrodiol dehydrogenase activity	Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol.	got7fsn_ti												UM-BBD_enzymeID:e0411		molecular_function											owl:Class	
GO:0072664	biolink:NamedThing	maintenance of protein location in peroxisome	Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.	got7fsn_ti							mah	2011-02-14T02:51:51Z						biological_process											owl:Class	
GO:0102841	biolink:NamedThing	1-18:1-2-16:2-monogalactosyldiacylglycerol synthase activity	Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:1-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8302|EC:1.14.19.23		molecular_function											owl:Class	
GO:0097095	biolink:NamedThing	frontonasal suture morphogenesis	The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized.	got7fsn_ti	nasofrontal suture morphogenesis						pr	2011-07-05T02:57:46Z						biological_process											owl:Class	
GO:0072013	biolink:NamedThing	glomus development	The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.	got7fsn_ti	pronephric glomus development						mah	2010-01-25T02:23:19Z						biological_process											owl:Class	
GO:0019934	biolink:NamedThing	cGMP-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.	got7fsn_ti	cGMP-mediated signalling													biological_process											owl:Class	
GO:0019817	biolink:NamedThing	vesicle fusion with peroxisome	The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.	got7fsn_ti														biological_process											owl:Class	
GO:0039670	biolink:NamedThing	viral capsid, turret	A turret-like appendage formed at the vertices of an icosahedral capsid.	got7fsn_ti							bf	2013-09-25T10:08:14Z						cellular_component											owl:Class	
GO:0032635	biolink:NamedThing	interleukin-6 production	The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-6 secretion|interleukin-6 biosynthetic process|IL-6 production										GO:0042226|GO:0072604			biological_process											owl:Class	
GO:0061979	biolink:NamedThing	femoral head articular cartilage development	The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure.	got7fsn_ti							dph	2018-02-12T20:06:21Z						biological_process											owl:Class	
GO:0061977	biolink:NamedThing	hip joint articular cartilage development	The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure.	got7fsn_ti							dph	2018-02-12T20:03:22Z						biological_process											owl:Class	
GO:0072444	biolink:NamedThing	response to mitotic DNA replication checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling.	got7fsn_ti	response to S-M checkpoint signaling|S-M checkpoint effector process|response to signal involved in mitotic DNA replication checkpoint|response to signal involved in S-M checkpoint|mitotic DNA replication checkpoint effector process						mah	2010-12-08T05:13:27Z			GO:0072447			biological_process											owl:Class	
GO:0034981	biolink:NamedThing	FHL3-CREB complex	A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation.	got7fsn_ti														cellular_component											owl:Class	
GO:0050392	biolink:NamedThing	vicianin beta-glucosidase activity	Catalysis of the reaction: (R)-vicianin + H(2)O = mandelonitrile + vicianose.	got7fsn_ti	vicianin b-glucosidase activity|(R)-vicianin beta-D-glucohydrolase activity|vicianin hydrolase activity											KEGG_REACTION:R03642|RHEA:14041|EC:3.2.1.119|MetaCyc:VICIANIN-BETA-GLUCOSIDASE-RXN		molecular_function											owl:Class	
GO:0030262	biolink:NamedThing	apoptotic nuclear changes	Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.	got7fsn_ti	apoptotic nuclear change													biological_process											owl:Class	
GO:0006921	biolink:NamedThing	cellular component disassembly involved in execution phase of apoptosis	The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.	got7fsn_ti	cellular component disassembly involved in apoptosis|cellular component disassembly involved in apoptotic process|disassembly of cell structures													biological_process											owl:Class	
GO:1990104	biolink:NamedThing	DNA bending complex	A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction.	got7fsn_ti	histone-like DNA binding complex						bhm	2013-05-20T09:29:06Z						cellular_component											owl:Class	
GO:0070504	biolink:NamedThing	selenium-containing prosthetic group biosynthetic process	The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.	got7fsn_ti	selenium-containing prosthetic group synthesis|selenium-containing prosthetic group formation|selenium-containing prosthetic group anabolism|selenium-containing prosthetic group biosynthesis													biological_process											owl:Class	
GO:0047296	biolink:NamedThing	homospermidine synthase activity	Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine.	got7fsn_ti	putrescine:putrescine 4-aminobutyltransferase (ammonia-forming)											MetaCyc:2.5.1.44-RXN|EC:2.5.1.44|RHEA:18645		molecular_function											owl:Class	
GO:0051694	biolink:NamedThing	pointed-end actin filament capping	The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.	got7fsn_ti	minus-end F-actin capping activity|pointed-end actin capping activity|minus-end actin filament capping activity|pointed-end F-actin capping activity													biological_process											owl:Class	
GO:1904253	biolink:NamedThing	positive regulation of bile acid metabolic process	Any process that activates or increases the frequency, rate or extent of bile acid metabolic process.	got7fsn_ti	positive regulation of bile acid metabolism|activation of bile acid metabolism|upregulation of bile acid metabolic process|upregulation of bile acid metabolism|up regulation of bile acid metabolic process|activation of bile acid metabolic process|up-regulation of bile acid metabolic process|up regulation of bile acid metabolism|up-regulation of bile acid metabolism						bf	2015-05-20T11:04:40Z						biological_process											owl:Class	
GO:0019540	biolink:NamedThing	catechol-containing siderophore biosynthetic process	The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. Catechol is one of the three major chemical groups incorporated into siderophore structures with hydroxamate and a-hydroxycarboxylate, each having a high selectivity for iron(3+).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20975									GO:0031190|GO:0031189			biological_process											owl:Class	
GO:0016555	biolink:NamedThing	uridine to cytidine editing	The conversion of a uridine residue to cytosine in an RNA molecule by amination.	got7fsn_ti														biological_process											owl:Class	
GO:1990007	biolink:NamedThing	membrane stack	A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures.	got7fsn_ti							pr	2012-12-11T14:58:16Z				NIF_Subcellular:sao2114874506		cellular_component											owl:Class	
GO:0001015	biolink:NamedThing	snoRNA transcription by RNA polymerase II	The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.	got7fsn_ti	snoRNA transcription from an RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14854					krc	2010-08-18T07:21:18Z						biological_process											owl:Class	
GO:0010672	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter, meiotic|regulation of meiosis by regulation of transcription from RNA polymerase II promoter						mah	2012-04-20T02:45:12Z			GO:1900401			biological_process											owl:Class	
GO:0051037	biolink:NamedThing	regulation of transcription involved in meiotic cell cycle	Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle.	got7fsn_ti	meiotic regulation of transcription|regulation of transcription, meiotic													biological_process											owl:Class	
GO:1902903	biolink:NamedThing	regulation of supramolecular fiber organization	Any process that modulates the frequency, rate or extent of supramolecular fiber organization.	got7fsn_ti	regulation of fibril organisation				HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro		rl	2014-04-15T16:46:36Z						biological_process											owl:Class	
GO:0004502	biolink:NamedThing	kynurenine 3-monooxygenase activity	Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+).	got7fsn_ti	L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)|kynurenine hydroxylase activity|L-kynurenine-3-hydroxylase activity|kynurenine 3-hydroxylase activity											RHEA:20545|KEGG_REACTION:R01960|MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN|Reactome:R-HSA-71200|EC:1.14.13.9		molecular_function											owl:Class	
GO:0004565	biolink:NamedThing	beta-galactosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.	got7fsn_ti	beta-lactosidase activity|oryzatym|beta-D-galactanase activity|hydrolact|lactose hydrolysis|maxilact|exo-(1->4)-beta-D-galactanase activity|lactozym|trilactase activity|beta-D-galactoside galactohydrolase activity|S 2107|sumiklat|beta-D-lactosidase activity				Note that the inclusion of 'MetaCyc:BGALACT-PWY' is exceptional: normally MetaCyc pathway entries are database references for biological process terms, not molecular function terms. An exception was made in this case because the MetaCyc entry 'BGALACT-PWY' describes only one reaction, that catalyzed by beta-galactosidase.							Reactome:R-HSA-2265534|Reactome:R-HSA-2090079|Reactome:R-HSA-9036061|MetaCyc:3.2.1.23-RXN|Reactome:R-HSA-1606312|EC:3.2.1.23|Reactome:R-HSA-1793217|MetaCyc:BGALACT-PWY|Reactome:R-HSA-1605624|Reactome:R-HSA-1630306		molecular_function											owl:Class	
GO:0046258	biolink:NamedThing	anaerobic 2,4,6-trinitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen.	got7fsn_ti	anaerobic 2,4,6-trinitrotoluene breakdown|anaerobic 2,4,6-trinitrotoluene degradation|anaerobic 2,4,6-trinitrotoluene catabolism													biological_process											owl:Class	
GO:0046256	biolink:NamedThing	2,4,6-trinitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.	got7fsn_ti	2,4,6-trinitrotoluene degradation|2,4,6-trinitrotoluene breakdown|2,4,6-trinitrotoluene catabolism													biological_process											owl:Class	
GO:0009543	biolink:NamedThing	chloroplast thylakoid lumen	The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana.	got7fsn_ti														cellular_component											owl:Class	
GO:1990314	biolink:NamedThing	cellular response to insulin-like growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.	got7fsn_ti	cellular response to insulin-like growth factor						sl	2014-03-07T19:38:21Z						biological_process											owl:Class	
GO:0050289	biolink:NamedThing	spermidine dehydrogenase activity	Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor.	got7fsn_ti	spermidine:(acceptor) oxidoreductase activity|spermidine:acceptor oxidoreductase activity											EC:1.5.99.6|MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN|RHEA:14273		molecular_function											owl:Class	
GO:2000211	biolink:NamedThing	regulation of glutamate metabolic process	Any process that modulates the frequency, rate or extent of glutamate metabolic process.	got7fsn_ti	regulation of glutamic acid metabolic process|regulation of glutamate metabolism|regulation of glutamic acid metabolism						mah	2010-11-03T02:43:51Z						biological_process											owl:Class	
GO:0000820	biolink:NamedThing	regulation of glutamine family amino acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.	got7fsn_ti	regulation of glutamine family amino acid metabolism													biological_process											owl:Class	
GO:0008811	biolink:NamedThing	chloramphenicol O-acetyltransferase activity	Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA.	got7fsn_ti	CAT I|chloramphenicol transacetylase activity|CAT III|CAT II|chloramphenicol acetyltransferase activity|acetyl-CoA:chloramphenicol 3-O-acetyltransferase activity|chloramphenicol acetylase activity											EC:2.3.1.28|KEGG_REACTION:R03065|RHEA:18421|MetaCyc:CHLORAMPHENICOL-O-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0030041	biolink:NamedThing	actin filament polymerization	Assembly of actin filaments by the addition of actin monomers to a filament.	got7fsn_ti	actin polymerization|actin polymerizing activity													biological_process											owl:Class	
GO:0060972	biolink:NamedThing	left/right pattern formation	The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.	got7fsn_ti							dph	2009-10-06T10:25:58Z						biological_process											owl:Class	
GO:2000082	biolink:NamedThing	regulation of L-ascorbic acid biosynthetic process	Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process.	got7fsn_ti	regulation of L-ascorbic acid formation|regulation of L-ascorbic acid biosynthesis|regulation of L-ascorbic acid synthesis|regulation of ascorbate biosynthetic process|regulation of vitamin C biosynthetic process|regulation of ascorbate biosynthesis|regulation of L-ascorbic acid anabolism|regulation of vitamin C biosynthesis						tb	2010-08-27T11:26:16Z						biological_process											owl:Class	
GO:0005056	biolink:NamedThing	tiggrin receptor activity	Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0110143	biolink:NamedThing	magnetosome	A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles.	got7fsn_ti							kmv	2019-05-30T17:31:21Z						cellular_component											owl:Class	
GO:0071009	biolink:NamedThing	U4atac/U6atac x U5 tri-snRNP complex	A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs.	got7fsn_ti	U4atac/U6atac.U5 snRNP complex						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0047341	biolink:NamedThing	fucose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP = diphosphate + GDP-L-fucose.	got7fsn_ti	GDP-L-fucose pyrophosphorylase activity|GDP fucose pyrophosphorylase activity|GDP-fucose diphosphorylase activity|guanosine diphosphate L-fucose pyrophosphorylase activity|GTP:beta-L-fucose-1-phosphate guanylyltransferase activity|GDP-fucose pyrophosphorylase activity|GTP:L-fucose-1-phosphate guanylyltransferase activity|GTP:fucose-1-phosphate guanylyltransferase activity											EC:2.7.7.30|Reactome:R-HSA-6787533|RHEA:13549|MetaCyc:2.7.7.30-RXN|KEGG_REACTION:R01951		molecular_function											owl:Class	
GO:0098600	biolink:NamedThing	selenomethionine gamma-lyase activity	Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid.	got7fsn_ti							dos	2014-04-15T15:00:28Z				Reactome:R-HSA-2408537		molecular_function											owl:Class	
GO:0047500	biolink:NamedThing	(+)-borneol dehydrogenase activity	Catalysis of the reaction: (+)-borneol + NAD(+) = (1R, 4R)-camphor + H(+) + NADH.	got7fsn_ti	(+)-borneol:NAD+ oxidoreductase activity|bicyclic monoterpenol dehydrogenase activity											KEGG_REACTION:R02944|EC:1.1.1.198|RHEA:17329|MetaCyc:+-BORNEOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0008814	biolink:NamedThing	citrate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.	got7fsn_ti	acetyl-CoA:citrate CoA-transferase activity											MetaCyc:CITTRANS-RXN|EC:2.8.3.10|RHEA:19405		molecular_function											owl:Class	
GO:0007192	biolink:NamedThing	adenylate cyclase-activating serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	got7fsn_ti	activation of adenylate cyclase activity by serotonin receptor signalling pathway|serotonin receptor, adenylate cyclase activating pathway|serotonin receptor, adenylyl cyclase activating pathway													biological_process											owl:Class	
GO:0090423	biolink:NamedThing	phytochelatin-metal complex formation	A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex.	got7fsn_ti	low molecular weight phytochelatin complex formation|LWM phytochelatin complex formation						tb	2012-04-20T03:46:45Z						biological_process											owl:Class	
GO:0103062	biolink:NamedThing	cis-keto-C60-meroacyl-AMP ligase activity	Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] <=> diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN1G-4142		molecular_function											owl:Class	
GO:2000870	biolink:NamedThing	regulation of progesterone secretion	Any process that modulates the frequency, rate or extent of progesterone secretion.	got7fsn_ti							bf	2011-07-26T08:51:14Z						biological_process											owl:Class	
GO:0071246	biolink:NamedThing	cellular response to chlorate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.	got7fsn_ti							mah	2009-12-03T02:45:36Z						biological_process											owl:Class	
GO:0034264	biolink:NamedThing	isopentenyl adenine metabolic process	The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine.	got7fsn_ti	isopentenyladenine metabolic process|isopentenyl adenine metabolism													biological_process											owl:Class	
GO:0102412	biolink:NamedThing	valerena-4,7(11)-diene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> valerena-4,7(11)-diene + diphosphoric acid.	got7fsn_ti												RHEA:34467|EC:4.2.3.139|MetaCyc:RXN-13769		molecular_function											owl:Class	
GO:0140022	biolink:NamedThing	cnida	A giant secretory organelle that comprises a bulb-shape capsule containing a coiled hollow tubule structure attached to it. A cnida defines the phylum Cnidaria.	got7fsn_ti	cnidae (plural)						cjm	2017-04-12T15:12:20Z						cellular_component											owl:Class	
GO:0018560	biolink:NamedThing	protocatechuate 3,4-dioxygenase type II activity	Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0581		molecular_function											owl:Class	
GO:0030116	biolink:NamedThing	glial cell-derived neurotrophic factor receptor binding	A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors.	got7fsn_ti	glial cell line-derived neurotrophic factor receptor binding|glial cell line-derived neurotrophic factor receptor ligand													molecular_function											owl:Class	
GO:0060931	biolink:NamedThing	sinoatrial node cell development	The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.	got7fsn_ti	SAN cell development|sinus node cell development|SA node cell development						dph	2009-09-29T12:05:47Z						biological_process											owl:Class	
GO:0031059	biolink:NamedThing	histone deacetylation at centromere	The removal of acetyl groups from histones in centromeric DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0110058	biolink:NamedThing	positive regulation of blood vessel endothelial cell differentiation	Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation.	got7fsn_ti							kmv	2017-10-23T14:38:19Z						biological_process											owl:Class	
GO:0045603	biolink:NamedThing	positive regulation of endothelial cell differentiation	Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation.	got7fsn_ti	upregulation of endothelial cell differentiation|stimulation of endothelial cell differentiation|activation of endothelial cell differentiation|up-regulation of endothelial cell differentiation|up regulation of endothelial cell differentiation													biological_process											owl:Class	
GO:0032407	biolink:NamedThing	MutSalpha complex binding	Binding to a MutSalpha mismatch repair complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0008209	biolink:NamedThing	androgen metabolic process	The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.	got7fsn_ti	androgen metabolism													biological_process											owl:Class	
GO:0010475	biolink:NamedThing	galactose-1-phosphate guanylyltransferase (GDP) activity	Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose.	got7fsn_ti	GDP:galactose-1-phosphate guanyltransferase activity													molecular_function											owl:Class	
GO:0035697	biolink:NamedThing	CD8-positive, alpha-beta T cell extravasation	The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue.	got7fsn_ti							bf	2011-02-28T03:08:49Z						biological_process											owl:Class	
GO:0004579	biolink:NamedThing	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.	got7fsn_ti	dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity|dolichyldiphosphooligosaccharide-protein glycosyltransferase activity|dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity|dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity|dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity|oligomannosyltransferase activity|dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity|asparagine N-glycosyltransferase activity											Reactome:R-HSA-9694793|Reactome:R-HSA-446209|MetaCyc:2.4.1.119-RXN|RHEA:22980|EC:2.4.99.18		molecular_function											owl:Class	
GO:0004576	biolink:NamedThing	oligosaccharyl transferase activity	Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid.	got7fsn_ti	oligosaccharide transferase activity													molecular_function											owl:Class	
GO:0018063	biolink:NamedThing	cytochrome c-heme linkage	The linkage of cytochromes and other heme proteins to heme.	got7fsn_ti	cytochrome c-haem linkage											RESID:AA0134|RESID:AA0135		biological_process											owl:Class	
GO:0042322	biolink:NamedThing	negative regulation of circadian sleep/wake cycle, REM sleep	Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep.	got7fsn_ti	inhibition of circadian sleep/wake cycle, REM sleep|negative regulation of REM sleep|downregulation of circadian sleep/wake cycle, REM sleep|down regulation of circadian sleep/wake cycle, REM sleep|down-regulation of circadian sleep/wake cycle, REM sleep													biological_process											owl:Class	
GO:2000859	biolink:NamedThing	negative regulation of aldosterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion.	got7fsn_ti							bf	2011-07-26T08:47:31Z						biological_process											owl:Class	
GO:0050194	biolink:NamedThing	phosphonoacetaldehyde hydrolase activity	Catalysis of the reaction: H(2)O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate.	got7fsn_ti	phosphonoacetylaldehyde phosphonohydrolase activity|2-oxoethylphosphonate phosphonohydrolase activity|2-phosphonoacetylaldehyde phosphonohydrolase activity|phosphonatase activity											KEGG_REACTION:R00747|EC:3.11.1.1|RHEA:18905|MetaCyc:PHOSPHONOACETALDEHYDE-HYDROLASE-RXN		molecular_function											owl:Class	
GO:0044070	biolink:NamedThing	regulation of anion transport	Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1903792	biolink:NamedThing	negative regulation of anion transport	Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.	got7fsn_ti	downregulation of anion transport|down-regulation of anion transport|inhibition of anion transport|down regulation of anion transport						sl	2015-01-12T21:50:20Z						biological_process											owl:Class	
GO:0036322	biolink:NamedThing	pancreatic polypeptide secretion	The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas.	got7fsn_ti	PP secretion						bf	2012-09-04T14:39:03Z						biological_process											owl:Class	
GO:0043366	biolink:NamedThing	beta selection	The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell.	got7fsn_ti														biological_process											owl:Class	
GO:0007112	biolink:NamedThing	male meiosis cytokinesis	A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells.	got7fsn_ti	cytokinesis after male meiosis|cytokinesis involved in male meiotic cell cycle													biological_process											owl:Class	
GO:0098928	biolink:NamedThing	presynaptic signal transduction	Signal transduction in which the initial step occurs in a presynapse.	got7fsn_ti	presynaptic signaling pathway				Do not directly annotate. This term intended for grouping.  Annotate to either a subclass or to some other subclass of signal transduction  extended with has_start_location/occurs_in presynapse or one of its parts.  Such extensions will result in automatic annotation to this term.									biological_process											owl:Class	
GO:0110134	biolink:NamedThing	meiotic drive	A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis.	got7fsn_ti							kmv	2019-01-02T17:37:09Z						biological_process											owl:Class	
GO:0034896	biolink:NamedThing	3-formiminopyruvate hydrolase activity	Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3.	got7fsn_ti												UM-BBD_reactionID:r1400|EC:3.5.99.-		molecular_function											owl:Class	
GO:0016158	biolink:NamedThing	3-phytase activity	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.	got7fsn_ti	phytase activity|myo-inositol-hexakisphosphate 3-phosphohydrolase activity|myo-inositol-hexaphosphate 3-phosphohydrolase activity|1-phytase activity|phytate 1-phosphatase activity|phytate 3-phosphatase activity											EC:3.1.3.8|MetaCyc:RXN0-1001|RHEA:16989		molecular_function											owl:Class	
GO:0045576	biolink:NamedThing	mast cell activation	The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.	got7fsn_ti														biological_process											owl:Class	
GO:0018823	biolink:NamedThing	cyclohexa-1,5-dienecarbonyl-CoA hydratase activity	Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA.	got7fsn_ti	cyclohexa-1,5-diene-1-carboxyl-CoA hydratase activity|6-hydroxycyclohex-1-enecarbonyl-CoA (cyclohexa-1,5-dienecarbonyl-CoA-forming)|cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase activity|dienoyl-CoA hydratase activity|cyclohex-1,5-diene-1-carbonyl-CoA hydratase activity|cyclohexa-1,5-diene-1-carbonyl-CoA hydratase activity											MetaCyc:4.2.1.100-RXN|EC:4.2.1.100|RHEA:21856|KEGG_REACTION:R05597|UM-BBD_reactionID:r0203		molecular_function											owl:Class	
GO:0052332	biolink:NamedThing	modification by organism of membrane in other organism involved in symbiotic interaction	The process in which an organism effects a change in the structure or function of a cellular membrane of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modification by organism of cell membrane in other organism involved in symbiotic interaction|modification by organism of cell membrane in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0048627	biolink:NamedThing	myoblast development	The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0102816	biolink:NamedThing	UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside <=> H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP.	got7fsn_ti												RHEA:35423|EC:2.4.1.298|MetaCyc:RXN-8234		molecular_function											owl:Class	
GO:0042245	biolink:NamedThing	RNA repair	Any process that results in the repair of damaged RNA.	got7fsn_ti														biological_process											owl:Class	
GO:0004450	biolink:NamedThing	isocitrate dehydrogenase (NADP+) activity	Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+.	got7fsn_ti	NADP-specific isocitrate dehydrogenase activity|isocitrate (NADP) dehydrogenase activity|dual-cofactor-specific isocitrate dehydrogenase activity|NADP(+)-linked isocitrate dehydrogenase activity|NADP-dependent isocitrate dehydrogenase activity|isocitrate dehydrogenase (NADP-dependent) activity|NADP-linked isocitrate dehydrogenase activity|NADP isocitric dehydrogenase activity|isocitrate dehydrogenase (NADP) activity|NADP(+)-ICDH activity|isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity|NADP-dependent isocitric dehydrogenase activity|isocitrate:NADP+ oxidoreductase (decarboxylating)|NADP(+)-IDH activity											Reactome:R-HSA-450984|Reactome:R-HSA-389550|Reactome:R-HSA-389540|RHEA:19629|EC:1.1.1.42|MetaCyc:ISOCITDEH-RXN		molecular_function											owl:Class	
GO:0097703	biolink:NamedThing	cellular response to pulsatile fluid shear stress	Any response to pulsatile fluid shear stress that occurs at the level of a cell.	got7fsn_ti							pr	2016-01-27T14:18:23Z						biological_process											owl:Class	
GO:0050528	biolink:NamedThing	acyloxyacyl hydrolase activity	Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.	got7fsn_ti												EC:3.1.1.77|RHEA:12032|MetaCyc:3.1.1.77-RXN		molecular_function											owl:Class	
GO:0102934	biolink:NamedThing	costunolide synthase activity	Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP.	got7fsn_ti												RHEA:28230|MetaCyc:RXN-8971|EC:1.14.14.150		molecular_function											owl:Class	
GO:0005046	biolink:NamedThing	KDEL sequence binding	Binding to a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.	got7fsn_ti	KDEL receptor activity													molecular_function											owl:Class	
GO:0043456	biolink:NamedThing	regulation of pentose-phosphate shunt	Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis.	got7fsn_ti	regulation of pentose phosphate pathway|regulation of pentose-phosphate pathway|regulation of pentose phosphate shunt													biological_process											owl:Class	
GO:0120055	biolink:NamedThing	small intestinal transit	Migration of ingested material along the length of the small intestine.	got7fsn_ti	small intestine transit|small bowel transit						krc	2017-06-13T20:46:41Z						biological_process											owl:Class	
GO:0039675	biolink:NamedThing	exit of virus from host cell nucleus through nuclear pore	The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore.	got7fsn_ti	viral enome export through nuclear pore|exit of virus from host cell nucleus through nuclear pore complex|nuclear pore exit of virus						bf	2013-09-25T14:10:03Z				VZ:1953		biological_process											owl:Class	
GO:0097753	biolink:NamedThing	membrane bending	A membrane organization process resulting in the bending of a membrane.	got7fsn_ti	membrane curvature						pr	2017-01-25T16:37:06Z						biological_process											owl:Class	
GO:0102360	biolink:NamedThing	daphnetin 3-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 7,8-dihydroxycoumarin <=> UDP(3-) + 3-O-beta-D-glucosyl-daphnetin + H+.	got7fsn_ti												EC:2.4.1.91|MetaCyc:RXN-13452		molecular_function											owl:Class	
GO:0008190	biolink:NamedThing	eukaryotic initiation factor 4E binding	Binding to eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.	got7fsn_ti	eIF4E binding													molecular_function											owl:Class	
GO:0031369	biolink:NamedThing	translation initiation factor binding	Binding to a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.	got7fsn_ti														molecular_function											owl:Class	
GO:0060131	biolink:NamedThing	corticotropin hormone secreting cell development	The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.	got7fsn_ti	corticotrophin hormone secreting cell development|corticotrope development|corticotroph development|adrenocorticotropic hormone secreting cell development|adrenocorticotrophic hormone secreting cell development													biological_process											owl:Class	
GO:0099611	biolink:NamedThing	regulation of action potential firing threshold	Any process that regulates the potential at which an axon potential is triggered.	got7fsn_ti														biological_process											owl:Class	
GO:0021850	biolink:NamedThing	subpallium glioblast cell division	The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes.	got7fsn_ti	glioblast cell division in subpallium|glioblast division in ventral telencephalon													biological_process											owl:Class	
GO:0048860	biolink:NamedThing	glioblast division	The process resulting in the physical partitioning and separation of a glioblast into daughter cells.	got7fsn_ti														biological_process											owl:Class	
GO:0098626	biolink:NamedThing	methylseleninic acid reductase activity	Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.	got7fsn_ti												Reactome:R-HSA-5263616		molecular_function											owl:Class	
GO:0072587	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity	Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.	got7fsn_ti							mah	2011-02-09T05:34:47Z						molecular_function											owl:Class	
GO:0001671	biolink:NamedThing	ATPase activator activity	Binds to and increases the activity of an ATP hydrolysis activity.	got7fsn_ti	ATPase stimulator activity	https://github.com/geneontology/go-ontology/issues/20955										Reactome:R-HSA-5251955|Reactome:R-HSA-5251959		molecular_function											owl:Class	
GO:0000472	biolink:NamedThing	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.	got7fsn_ti	endonucleolytic cleavage at A1													biological_process											owl:Class	
GO:0031554	biolink:NamedThing	regulation of DNA-templated transcription, termination	Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.	got7fsn_ti	transcription antiterminator activity|regulation of DNA-dependent transcription, termination|regulation of termination of DNA-dependent transcription|regulation of transcription termination, DNA-dependent													biological_process											owl:Class	
GO:0102476	biolink:NamedThing	pinocembrin 2-hydroxylase activity	Catalysis of the reaction: pinocembrin + NADPH + O2 + H+ <=> 2,5,7-trihydroxyflavanone + NADP + H2O.	got7fsn_ti												RHEA:57592|MetaCyc:RXN-14083		molecular_function											owl:Class	
GO:0009027	biolink:NamedThing	tartrate dehydrogenase activity	Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+.	got7fsn_ti	mesotartrate dehydrogenase activity|tartrate:NAD+ oxidoreductase activity											RHEA:15209|MetaCyc:TARTRATE-DEHYDROGENASE-RXN|EC:1.1.1.93		molecular_function											owl:Class	
GO:0052001	biolink:NamedThing	type IV pili-dependent localized adherence to host	Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0043466	biolink:NamedThing	pyrimidine nucleobase fermentation	The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP.	got7fsn_ti	pyrimidine base fermentation|pyrimidine fermentation													biological_process											owl:Class	
GO:0019666	biolink:NamedThing	nitrogenous compound fermentation	The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.	got7fsn_ti	nitrogenous compound catabolic process													biological_process											owl:Class	
GO:0070935	biolink:NamedThing	3'-UTR-mediated mRNA stabilization	An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.	got7fsn_ti	3'-untranslated region-mediated mRNA stabilization						mah	2009-09-21T03:08:20Z						biological_process											owl:Class	
GO:0097718	biolink:NamedThing	disordered domain specific binding	Binding to a disordered domain of a protein.	got7fsn_ti	disordered protein domain specific binding						pr	2016-08-23T16:42:51Z						molecular_function											owl:Class	
GO:0098628	biolink:NamedThing	peptidyl-N-phospho-arginine dephosphorylation	The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine.	got7fsn_ti							dos	2014-04-17T18:03:31Z						biological_process											owl:Class	
GO:0008612	biolink:NamedThing	peptidyl-lysine modification to peptidyl-hypusine	The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.	got7fsn_ti	hypusinylation|hypusine formation|protein hypusination|hypusine formation from peptidyl-lysine|hypusine biosynthetic process from peptidyl-lysine|hypusine synthesis from peptidyl-lysine|hypusine biosynthesis|hypusine anabolism from peptidyl-lysine|hypusine biosynthetic process|hypusine anabolism|hypusine synthesis										GO:0046515	RESID:AA0116		biological_process											owl:Class	
GO:0043580	biolink:NamedThing	periplasmic space organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi.	got7fsn_ti	periplasmic space organization and biogenesis|periplasmic space organisation													biological_process											owl:Class	
GO:0070593	biolink:NamedThing	dendrite self-avoidance	The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.	got7fsn_ti	dendrite repulsion						mah	2009-04-28T03:29:14Z						biological_process											owl:Class	
GO:0032169	biolink:NamedThing	prospore septin ring	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0008628	biolink:NamedThing	hormone-mediated apoptotic signaling pathway	A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered.	got7fsn_ti	induction of apoptosis by hormones|apoptotic signaling pathway in response to hormone	http://wiki.geneontology.org/index.php/Apoptosis_Curation_Manual#Other_children_of_apoptotic_signaling_pathway			This term is placed under GO:0097190 apoptotic signaling pathway, rather than under one of its more specific children terms, to cover for the variety of apoptosis signaling mechanisms that different hormones may use.									biological_process											owl:Class	
GO:0035843	biolink:NamedThing	endonuclear canal	A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope.	got7fsn_ti							bf	2011-05-06T01:45:03Z						cellular_component											owl:Class	
GO:0033722	biolink:NamedThing	malonate-semialdehyde dehydrogenase activity	Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+.	got7fsn_ti	malonic semialdehyde dehydrogenase activity|3-oxopropanoate:NAD(P)+ oxidoreductase activity											EC:1.2.1.15|MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0008157	biolink:NamedThing	protein phosphatase 1 binding	Binding to a protein phosphatase 1.	got7fsn_ti														molecular_function											owl:Class	
GO:0044728	biolink:NamedThing	DNA methylation or demethylation	The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.	got7fsn_ti	changes in DNA methylation						jl	2012-10-24T14:49:41Z						biological_process											owl:Class	
GO:0002030	biolink:NamedThing	inhibitory G protein-coupled receptor phosphorylation	The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site.	got7fsn_ti	inhibitory G-protein coupled receptor phosphorylation													biological_process											owl:Class	
GO:0047260	biolink:NamedThing	alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity	Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP.	got7fsn_ti	GDP-glucose-glucosephosphate glucosyltransferase activity|GDPglucose-glucose-phosphate glucosyltransferase activity|GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|guanosine diphosphoglucose-glucose phosphate glucosyltransferase activity|GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|trehalose phosphate synthase (GDP-forming) activity											RHEA:14605|EC:2.4.1.36|MetaCyc:2.4.1.36-RXN		molecular_function											owl:Class	
GO:0061197	biolink:NamedThing	fungiform papilla morphogenesis	The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.	got7fsn_ti							dph	2010-07-27T12:26:40Z						biological_process											owl:Class	
GO:0097238	biolink:NamedThing	cellular response to methylglyoxal	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.	got7fsn_ti							pr	2012-02-02T12:26:35Z						biological_process											owl:Class	
GO:0090167	biolink:NamedThing	Golgi distribution to daughter cells	Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division.	got7fsn_ti							tb	2009-12-08T09:15:11Z						biological_process											owl:Class	
GO:0051645	biolink:NamedThing	Golgi localization	Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	establishment and maintenance of Golgi localization|Golgi body localization|Golgi apparatus localization|Golgi localisation													biological_process											owl:Class	
GO:0097156	biolink:NamedThing	fasciculation of motor neuron axon	The collection of motor neuron axons into a bundle of rods, known as a fascicle.	got7fsn_ti							pr	2011-09-16T09:20:46Z						biological_process											owl:Class	
GO:0001122	biolink:NamedThing	promoter clearance from bacterial-type RNA polymerase promoter	Any process involved in the transition from the initiation to the elongation phase of transcription by a bacterial-type RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance generally involves dissociation of the sigma initiation factor.	got7fsn_ti							krc	2010-12-06T03:38:10Z						biological_process											owl:Class	
GO:0003086	biolink:NamedThing	regulation of systemic arterial blood pressure by local renal renin-angiotensin	The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen.	got7fsn_ti														biological_process											owl:Class	
GO:0052183	biolink:NamedThing	modification by host of symbiont structure	The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0022875	biolink:NamedThing	protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	galactitol PTS transporter activity													molecular_function											owl:Class	
GO:0015577	biolink:NamedThing	galactitol transmembrane transporter activity	Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	got7fsn_ti	galactitol permease activity										GO:0015588	RHEA:33143		molecular_function											owl:Class	
GO:0052750	biolink:NamedThing	reactive-black-5:hydrogen-peroxide oxidoreductase activity	Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O.	got7fsn_ti	versatile peroxidase activity						ai	2011-09-21T02:33:34Z				KEGG_REACTION:R07612|MetaCyc:RXN-8666|RHEA:22396|EC:1.11.1.16		molecular_function											owl:Class	
GO:0005091	biolink:NamedThing	guanyl-nucleotide exchange factor adaptor activity	The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way.	got7fsn_ti														molecular_function											owl:Class	
GO:0102115	biolink:NamedThing	peptidoglycan asparagine synthase activity	Catalysis of the reaction: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparatyl)-L-lysyl-D-alanyl-D-alanine + ammonium + ATP = H+ + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-11338		molecular_function											owl:Class	
GO:0017188	biolink:NamedThing	aspartate N-acetyltransferase activity	Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H(+).	got7fsn_ti	aspartate acetyltransferase activity|acetyl-CoA:L-aspartate N-acetyltransferase activity|L-aspartate N-acetyltransferase activity											MetaCyc:ASPARTATE-N-ACETYLTRANSFERASE-RXN|RHEA:14165|KEGG_REACTION:R00487|EC:2.3.1.17|Reactome:R-HSA-8954468		molecular_function											owl:Class	
GO:0060226	biolink:NamedThing	negative regulation of retinal cone cell fate commitment	Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.	got7fsn_ti														biological_process											owl:Class	
GO:0046533	biolink:NamedThing	negative regulation of photoreceptor cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	inhibition of photoreceptor differentiation|down-regulation of photoreceptor cell differentiation|downregulation of photoreceptor cell differentiation|negative regulation of photoreceptor differentiation|down-regulation of photoreceptor differentiation|inhibition of photoreceptor cell differentiation|downregulation of photoreceptor differentiation|down regulation of photoreceptor cell differentiation|down regulation of photoreceptor differentiation										GO:0045674			biological_process											owl:Class	
GO:1900806	biolink:NamedThing	ergot alkaloid catabolic process	The chemical reactions and pathways resulting in the breakdown of ergot alkaloid.	got7fsn_ti	ergot alkaloid catabolism|ergot alkaloids catabolism|ergot alkaloid degradation|ergot alkaloids catabolic process|ergot alkaloid breakdown|ergot alkaloids degradation|ergot alkaloids breakdown						di	2012-06-04T09:57:39Z						biological_process											owl:Class	
GO:0009784	biolink:NamedThing	transmembrane receptor histidine kinase activity	Combining with a signal and transmitting the signal from one side of a membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0019199	biolink:NamedThing	transmembrane receptor protein kinase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.	got7fsn_ti												Reactome:R-HSA-8983063|Reactome:R-HSA-8983059		molecular_function											owl:Class	
GO:0150056	biolink:NamedThing	amylin receptor complex 1	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).	got7fsn_ti	AMY1 complex						bc	2018-06-21T10:47:10Z						cellular_component											owl:Class	
GO:0061645	biolink:NamedThing	endocytic patch	The part of the cell cortex consisting of  an aggregation of proteins that will give rise to an endocytic vesicle.	got7fsn_ti							dph	2014-09-02T09:23:38Z						cellular_component											owl:Class	
GO:0061230	biolink:NamedThing	mesonephric juxtaglomerulus cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.	got7fsn_ti							dph	2010-08-19T02:36:23Z						biological_process											owl:Class	
GO:0019473	biolink:NamedThing	L-lysine catabolic process to glutarate, by acetylation	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation.	got7fsn_ti	L-lysine degradation to glutarate, by acetylation|L-lysine breakdown to glutarate, by acetylation											MetaCyc:LYSDEGII-PWY		biological_process											owl:Class	
GO:0019477	biolink:NamedThing	L-lysine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.	got7fsn_ti	L-lysine breakdown|L-lysine catabolism|L-lysine degradation													biological_process											owl:Class	
GO:0050547	biolink:NamedThing	vanillin synthase activity	Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin.	got7fsn_ti	3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase (acetyl-CoA-forming)|3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin-lyase (acetyl-CoA-forming)											MetaCyc:4.1.2.41-RXN|KEGG_REACTION:R05773|EC:4.1.2.61|RHEA:18725		molecular_function											owl:Class	
GO:0044314	biolink:NamedThing	protein K27-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.	got7fsn_ti	protein K27-linked polyubiquitination						jl	2010-06-02T11:48:08Z						biological_process											owl:Class	
GO:0000209	biolink:NamedThing	protein polyubiquitination	Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.	got7fsn_ti	polyubiquitin|protein polyubiquitylation|protein polyubiquitinylation													biological_process											owl:Class	
GO:0102624	biolink:NamedThing	scutellarein 7-methyl ether 4'-O-methyltransferase activity	Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine  <=> ladanein + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-15529		molecular_function											owl:Class	
GO:0050564	biolink:NamedThing	N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity	Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H(2)O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H(+).	got7fsn_ti	L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase activity|ACV synthetase activity|L-alpha-aminoadipyl-cysteinyl-valine synthetase activity|L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting)											MetaCyc:6.3.2.26-RXN|EC:6.3.2.26|KEGG_REACTION:R04870|RHEA:23196		molecular_function											owl:Class	
GO:0048882	biolink:NamedThing	lateral line development	The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.	got7fsn_ti	LL development													biological_process											owl:Class	
GO:0039690	biolink:NamedThing	positive stranded viral RNA replication	A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.	got7fsn_ti	ss(+) viral RNA replication						bf	2013-10-17T15:45:40Z				VZ:1116		biological_process											owl:Class	
GO:0140450	biolink:NamedThing	protein targeting to Golgi apparatus	The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).	got7fsn_ti							pg	2020-04-08T13:10:10Z						biological_process											owl:Class	
GO:0021806	biolink:NamedThing	initiation of movement involved in cerebral cortex radial glia guided migration	The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex.	got7fsn_ti	initiation of movement involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0047891	biolink:NamedThing	flavone 7-O-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone.	got7fsn_ti	UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose-luteolin beta-D-glucosyltransferase activity|uridine diphosphoglucose-luteolin glucosyltransferase activity|flavone 7-O-b-glucosyltransferase activity|uridine diphosphoglucose-apigenin 7-O-glucosyltransferase activity|UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity|UDP-glucose-apigenin beta-glucosyltransferase activity|UDP-glucose-luteolin beta-D-glucosyltransferase activity|UDPglucose-apigenin beta-glucosyltransferase activity											EC:2.4.1.81|RHEA:19577|MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0034841	biolink:NamedThing	mentha-1,3-dione-CoA ligase activity	Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r1186		molecular_function											owl:Class	
GO:0016584	biolink:NamedThing	nucleosome positioning	Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.	got7fsn_ti	nucleosome spacing													biological_process											owl:Class	
GO:0038001	biolink:NamedThing	paracrine signaling	The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.	got7fsn_ti	paracrine signalling				This term should be used with caution, and only used when the signaling between cells has been clearly distinguished from endocrine signaling.		bf	2011-02-25T02:11:00Z						biological_process											owl:Class	
GO:0017102	biolink:NamedThing	methionyl glutamyl tRNA synthetase complex	A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers.	got7fsn_ti														cellular_component											owl:Class	
GO:0044098	biolink:NamedThing	DNA secretion by the type IV secretion system	The controlled release of DNA by a cell, via the type IV secretion system.	got7fsn_ti	DNA secretion via the type IV secretion system						jl	2009-06-09T02:26:57Z						biological_process											owl:Class	
GO:0036352	biolink:NamedThing	histone H2A-K15 ubiquitination	The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin.	got7fsn_ti	histone H2A ubiquitination (H2A-K15)						bf	2012-09-19T11:49:03Z						biological_process											owl:Class	
GO:0070468	biolink:NamedThing	dentin extracellular matrix secretion	The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin.	got7fsn_ti	dentine secretion|dentin secretion|predentin secretion													biological_process											owl:Class	
GO:0045484	biolink:NamedThing	L-lysine 6-transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine.	got7fsn_ti	lysine epsilon-transaminase activity|L-lysine:2-oxoglutarate 6-aminotransferase activity|lysine:2-ketoglutarate 6-aminotransferase activity|L-lysine aminotransferase activity|lysine 6-aminotransferase activity|L-lysine-alpha-ketoglutarate 6-aminotransferase activity|L-lysine transaminase activity|L-lysine-alpha-ketoglutarate aminotransferase activity|lysine epsilon-aminotransferase activity											EC:2.6.1.36|MetaCyc:L-LYSINE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R00457|RHEA:21200		molecular_function											owl:Class	
GO:0072140	biolink:NamedThing	DCT cell development	The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure.	got7fsn_ti	distal convoluted tubule cell development						mah	2010-02-24T01:36:21Z						biological_process											owl:Class	
GO:0102723	biolink:NamedThing	UDP-glucose:curcumin glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-7062		molecular_function											owl:Class	
GO:2001001	biolink:NamedThing	negative regulation of xylan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process.	got7fsn_ti	negative regulation of xylan breakdown|negative regulation of xylan degradation|negative regulation of xylan catabolism						tt	2011-08-08T03:23:18Z						biological_process											owl:Class	
GO:0110052	biolink:NamedThing	toxic metabolite repair	A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.	got7fsn_ti							kmv	2017-09-08T15:19:16Z						biological_process											owl:Class	
GO:0110051	biolink:NamedThing	metabolite repair	A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.	got7fsn_ti							kmv	2017-09-08T15:16:01Z						biological_process											owl:Class	
GO:0045974	biolink:NamedThing	regulation of translation, ncRNA-mediated	Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein.	got7fsn_ti														biological_process											owl:Class	
GO:0099119	biolink:NamedThing	3-demethylubiquinol-8 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-8 = S-adenosyl-L-homocysteine + ubiquinol-8.	got7fsn_ti														molecular_function											owl:Class	
GO:0120097	biolink:NamedThing	glycosylphosphatidylinositol-mannosyltransferase II complex	A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p.	got7fsn_ti	GPI-MT-I complex						krc	2017-09-18T20:51:56Z						cellular_component											owl:Class	
GO:0050390	biolink:NamedThing	valine decarboxylase activity	Catalysis of the reaction: L-valine + H(+) = 2-methylpropanamine + CO(2).	got7fsn_ti	L-valine carboxy-lyase (2-methylpropanamine-forming)|leucine decarboxylase activity|L-valine carboxy-lyase activity											MetaCyc:VALINE-DECARBOXYLASE-RXN|RHEA:18989|UM-BBD_reactionID:r1052|EC:4.1.1.14|KEGG_REACTION:R01437		molecular_function											owl:Class	
GO:0004655	biolink:NamedThing	porphobilinogen synthase activity	Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen.	got7fsn_ti	5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)|delta-aminolevulinic dehydratase activity|delta-aminolevulinate dehydratase activity|delta-aminolevulinic acid dehydrase activity|5-levulinic acid dehydratase activity|aminolevulinate dehydratase activity|delta-aminolevulinic acid dehydratase activity|aminolevulinic dehydratase activity|5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)											EC:4.2.1.24|Reactome:R-HSA-189439|RHEA:24064|MetaCyc:PORPHOBILSYNTH-RXN|KEGG_REACTION:R00036		molecular_function											owl:Class	
GO:0102348	biolink:NamedThing	trans-docosan-2-enoyl-CoA reductase activity	Catalysis of the reaction: behenoyl-CoA + NADP <=> trans-2-docosenoyl-CoA + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13307		molecular_function											owl:Class	
GO:0010636	biolink:NamedThing	positive regulation of mitochondrial fusion	Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0006710	biolink:NamedThing	androgen catabolic process	The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.	got7fsn_ti	androgen degradation|androgen catabolism|androgen breakdown													biological_process											owl:Class	
GO:0047553	biolink:NamedThing	2-oxoglutarate synthase activity	Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin.	got7fsn_ti	alpha-ketoglutarate synthase activity|alpha-ketoglutarate-ferredoxin oxidoreductase activity|2-ketoglutarate ferredoxin oxidoreductase activity|2-oxoglutarate ferredoxin oxidoreductase activity|2-oxoglutarate:ferredoxin oxidoreductase activity|KGOR activity|2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating)|2-oxoglutarate:ferredoxin 2-oxidoreductase (decarboxylating)											EC:1.2.7.3|RHEA:17297|MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0018576	biolink:NamedThing	catechol 1,2-dioxygenase activity	Catalysis of the reaction: catechol + O2 = cis,cis-muconate.	got7fsn_ti	pyrocatechase activity|catechol 1,2-oxygenase activity|1,2-pyrocatechase activity|CD II|CD I|catechol-oxygen 1,2-oxidoreductase activity|pyrocatechol 1,2-dioxygenase activity|catechol:oxygen 1,2-oxidoreductase activity|catechase activity											EC:1.13.11.1|UM-BBD_enzymeID:e0064|MetaCyc:CATECHOL-12-DIOXYGENASE-RXN|RHEA:23852		molecular_function											owl:Class	
GO:0050095	biolink:NamedThing	methionine decarboxylase activity	Catalysis of the reaction: L-methionine + H(+) = 3-methylthiopropanamine + CO(2).	got7fsn_ti	L-methionine carboxy-lyase activity|L-methionine carboxy-lyase (3-methylthiopropanamine-forming)|L-methionine decarboxylase activity											RHEA:17757|KEGG_REACTION:R00656|MetaCyc:METHIONINE-DECARBOXYLASE-RXN|EC:4.1.1.57		molecular_function											owl:Class	
GO:0014811	biolink:NamedThing	negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.	got7fsn_ti														biological_process											owl:Class	
GO:0044081	biolink:NamedThing	modulation by symbiont of host nitric oxide-mediated signal transduction	Any process in which a symbiont organism modulates the rate, frequency or extent of nitric oxide mediated signal transduction in its host organism. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).	got7fsn_ti	modulation by symbiont of host nitric oxide mediated signal transduction|modulation of host nitric oxide-mediated signalling by symbiont|modulation of host nitric oxide-mediated signaling by symbiont|modulation of host nitric oxide-mediated signal transduction by symbiont|regulation by symbiont of host nitric oxide-mediated signal transduction													biological_process											owl:Class	
GO:0010749	biolink:NamedThing	regulation of nitric oxide mediated signal transduction	Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).	got7fsn_ti	regulation of nitric oxide-mediated signal transduction													biological_process											owl:Class	
GO:0140571	biolink:NamedThing	transmembrane ascorbate ferrireductase activity	Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.	got7fsn_ti	L-ascorbate-cytochrome-b5 reductase activity|L-ascorbate:ferricytochrome-b5 oxidoreductase activity|ascorbate-cytochrome b5 reductase activity						pg	2020-12-18T16:25:06Z				RHEA:30403|MetaCyc:1.10.2.1-RXN|EC:7.2.1.3		molecular_function											owl:Class	
GO:0071717	biolink:NamedThing	thromboxane transport	The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.	got7fsn_ti							mah	2010-03-10T03:03:49Z						biological_process											owl:Class	
GO:0038025	biolink:NamedThing	reelin receptor activity	Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	reeler receptor activity						bf	2011-08-02T12:01:25Z						molecular_function											owl:Class	
GO:0018632	biolink:NamedThing	4-nitrophenol 4-monooxygenase activity	Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone.	got7fsn_ti												RHEA:34327|MetaCyc:RXN-8739|UM-BBD_reactionID:r0226|EC:1.14.13.167		molecular_function											owl:Class	
GO:0102071	biolink:NamedThing	9,10-epoxy-18-hydroxystearate hydrolase activity	Catalysis of the reaction: 9,10-epoxy-18-hydroxystearate + H2O <=> 9,10,18-trihydroxystearate.	got7fsn_ti												MetaCyc:RXN-1065		molecular_function											owl:Class	
GO:0071291	biolink:NamedThing	cellular response to selenium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.	got7fsn_ti							mah	2009-12-10T04:15:52Z						biological_process											owl:Class	
GO:0018690	biolink:NamedThing	4-methoxybenzoate monooxygenase (O-demethylating) activity	Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O.	got7fsn_ti	piperonylate-4-O-demethylase activity|4-methoxybenzoate monooxygenase activity|p-anisic O-demethylase activity|4-methoxybenzoate,hydrogen-donor:oxygen oxidoreductase (O-demethylating)|4-methoxybenzoate O-demethylase activity|4-methoxybenzoate 4-monooxygenase (O-demethylating)											UM-BBD_reactionID:r0154|KEGG_REACTION:R01306|EC:1.14.99.15|RHEA:18613|MetaCyc:1.14.99.15-RXN		molecular_function											owl:Class	
GO:0046827	biolink:NamedThing	positive regulation of protein export from nucleus	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.	got7fsn_ti	positive regulation of protein-nucleus export|stimulation of protein export from nucleus|positive regulation of protein transport from nucleus to cytoplasm|positive regulation of protein export from cell nucleus|up-regulation of protein export from nucleus|activation of protein export from nucleus|up regulation of protein export from nucleus|positive regulation of protein export out of nucleus|upregulation of protein export from nucleus													biological_process											owl:Class	
GO:0015312	biolink:NamedThing	polyamine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).	got7fsn_ti	polyamine:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0000147	biolink:NamedThing	actin cortical patch assembly	Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.	got7fsn_ti														biological_process											owl:Class	
GO:0035663	biolink:NamedThing	Toll-like receptor 2 binding	Binding to a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.	got7fsn_ti	TLR2 binding						bf	2011-02-01T10:21:51Z						molecular_function											owl:Class	
GO:0046982	biolink:NamedThing	protein heterodimerization activity	Binding to a nonidentical protein to form a heterodimer.	got7fsn_ti														molecular_function											owl:Class	
GO:0036047	biolink:NamedThing	peptidyl-lysine demalonylation	The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein.	got7fsn_ti							bf	2011-12-12T09:39:17Z						biological_process											owl:Class	
GO:0036046	biolink:NamedThing	protein demalonylation	The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide.	got7fsn_ti							bf	2011-12-12T09:38:26Z						biological_process											owl:Class	
GO:0018137	biolink:NamedThing	peptide cross-linking via glycine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	got7fsn_ti												RESID:AA0241		biological_process											owl:Class	
GO:0071708	biolink:NamedThing	immunoglobulin light chain V-J recombination	The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).	got7fsn_ti	immunoglobulin V(D)J recombination|immunoglobulin V-J joining|immunoglobulin V(D)J joining						mah	2010-03-09T04:22:29Z						biological_process											owl:Class	
GO:0033152	biolink:NamedThing	immunoglobulin V(D)J recombination	The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.	got7fsn_ti	immunoglobulin V-D-J joining|immunoglobulin V(D)J joining|immunoglobulin V-D-J recombination|immunoglobulin V-J joining|immunoglobulin V-J recombination													biological_process											owl:Class	
GO:1990143	biolink:NamedThing	CoA-synthesizing protein complex	A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway.	got7fsn_ti	CoA-SPC|coenzyme A-synthesizing protein complex						rb	2013-07-18T22:30:20Z						cellular_component											owl:Class	
GO:0097158	biolink:NamedThing	pre-mRNA intronic pyrimidine-rich binding	Binding to a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA).	got7fsn_ti	pre-messenger RNA intronic pyrimidine-rich binding						pr	2011-09-23T11:29:03Z						molecular_function											owl:Class	
GO:0097157	biolink:NamedThing	pre-mRNA intronic binding	Binding to an intronic sequence of a pre-messenger RNA (pre-mRNA).	got7fsn_ti	pre-messenger RNA intronic binding						pr	2011-09-23T11:27:01Z						molecular_function											owl:Class	
GO:0034845	biolink:NamedThing	naphthyl-2-methyl-succinyl-CoA dehydrogenase activity	Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1258|EC:1.3.99.-		molecular_function											owl:Class	
GO:0061573	biolink:NamedThing	actin filament bundle retrograde transport	A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell.	got7fsn_ti	actin filament cable retrograde transport						dph	2013-08-02T11:31:04Z						biological_process											owl:Class	
GO:0072526	biolink:NamedThing	pyridine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.	got7fsn_ti	pyridine-containing compound breakdown|pyridine-containing compound catabolism|pyridine and derivative catabolic process|pyridine-containing compound degradation						mah	2011-01-04T03:23:14Z						biological_process											owl:Class	
GO:1903958	biolink:NamedThing	nitric-oxide synthase complex	A protein complex which is capable of nitric-oxide synthase activity.	got7fsn_ti	iNOS-S100A8/A9 complex				An example of this is NOS2 in human (P35228) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T10:45:01Z						cellular_component											owl:Class	
GO:2001079	biolink:NamedThing	beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding	Binding to beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc.	got7fsn_ti							jl	2011-09-15T01:15:19Z						molecular_function											owl:Class	
GO:0102833	biolink:NamedThing	sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity	Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> D-galactosylononitol + myo-inositol.	got7fsn_ti												MetaCyc:RXN-8292		molecular_function											owl:Class	
GO:0052851	biolink:NamedThing	ferric-chelate reductase (NADPH) activity	Catalysis of the reaction:  2 Fe3+-siderophore + NADP(+) + H(+) -> 2 Fe2+-siderophore + NADPH.	got7fsn_ti	ferric chelate reductase activity|iron chelate reductase activity|ferric reductase, NADPH-dependent activity	https://github.com/geneontology/go-ontology/issues/21029					ai	2011-12-05T11:04:23Z				KEGG_REACTION:R09541|RHEA:28795|EC:1.16.1.9|MetaCyc:RXN0-6555		molecular_function											owl:Class	
GO:0018453	biolink:NamedThing	2-hydroxytetrahydrofuran dehydrogenase activity	Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone.	got7fsn_ti												UM-BBD_reactionID:r0018		molecular_function											owl:Class	
GO:0004027	biolink:NamedThing	alcohol sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.	got7fsn_ti	sterol sulfokinase activity|steroid sulfokinase activity|3beta-hydroxy steroid sulfotransferase activity|alcohol/hydroxysteroid sulfotransferase activity|hydroxysteroid sulfotransferase activity|delta5-3beta-hydroxysteroid sulfokinase activity|3beta-hydroxysteroid sulfotransferase activity|3-hydroxysteroid sulfotransferase activity|dehydroepiandrosterone sulfotransferase activity|5alpha-androstenol sulfotransferase activity|estrogen sulfotransferase|3'-phosphoadenylyl-sulfate:alcohol sulfotransferase activity|steroid alcohol sulfotransferase|estrogen sulfokinase activity|alcohol sulphotransferase activity|HST|sterol sulfotransferase activity											Reactome:R-HSA-176494|MetaCyc:ALCOHOL-SULFOTRANSFERASE-RXN|Reactome:R-HSA-176609|EC:2.8.2.2|RHEA:22552		molecular_function											owl:Class	
GO:0018168	biolink:NamedThing	protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine	The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine.	got7fsn_ti												RESID:AA0132		biological_process											owl:Class	
GO:0047261	biolink:NamedThing	steroid N-acetylglucosaminyltransferase activity	Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H(+) + UDP.	got7fsn_ti	UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase activity|hydroxy steroid acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-steroid acetylglucosaminyltransferase activity|steroid acetylglucosaminyltransferase activity											EC:2.4.1.39|MetaCyc:2.4.1.39-RXN|RHEA:14153|KEGG_REACTION:R04451		molecular_function											owl:Class	
GO:0031415	biolink:NamedThing	NatA complex	A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins.	got7fsn_ti	N-terminal acetyltransferase A complex													cellular_component											owl:Class	
GO:0002199	biolink:NamedThing	zona pellucida receptor complex	A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction.	got7fsn_ti	sperm protein complex I						hjd	2011-12-23T01:33:23Z						cellular_component											owl:Class	
GO:0019863	biolink:NamedThing	IgE binding	Binding to an immunoglobulin of the IgE isotype.	got7fsn_ti														molecular_function											owl:Class	
GO:0033401	biolink:NamedThing	UUU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UUU codon.	got7fsn_ti	TTT codon-amino acid adaptor activity|phenylalanine tRNA				Note that in the standard genetic code, TTT codes for phenylalanine.									molecular_function											owl:Class	
GO:0009025	biolink:NamedThing	tagatose-bisphosphate aldolase activity	Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate.	got7fsn_ti	D-tagatose-1,6-bisphosphate triosephosphate lyase activity|AgaZ|tagatose-1,6-bisphosphate aldolase 1|KbaY|D-tagatose-1,6-bisphosphate aldolase activity|tagatose 1,6-diphosphate aldolase activity|AgaY|D-tagatose-1,6-bisphosphate D-glyceraldehyde 3-phosphate-lyase (glycerone-phosphate-forming)											MetaCyc:TAGAALDOL-RXN|RHEA:22948|KEGG_REACTION:R01069|EC:4.1.2.40		molecular_function											owl:Class	
GO:0031883	biolink:NamedThing	taste receptor binding	Binding to a taste receptor.	got7fsn_ti	taste receptor ligand													molecular_function											owl:Class	
GO:0016261	biolink:NamedThing	selenocysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.	got7fsn_ti	selenocysteine degradation|selenocysteine breakdown|selenocysteine catabolism													biological_process											owl:Class	
GO:0044103	biolink:NamedThing	L-arabinose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+.	got7fsn_ti							jl	2009-07-09T04:00:30Z				EC:1.1.1.376		molecular_function											owl:Class	
GO:0071967	biolink:NamedThing	lipopolysaccharide core heptosyltransferase activity	Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+.	got7fsn_ti	LPS core heptosyltransferase activity						mah	2010-10-14T05:13:31Z				MetaCyc:RXN0-5122|RHEA:29923		molecular_function											owl:Class	
GO:0034297	biolink:NamedThing	oidium formation	The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus.	got7fsn_ti														biological_process											owl:Class	
GO:0103044	biolink:NamedThing	ribosomal protein S6 glutamate-glutamate ligase activity	Catalysis of the reaction: L-glutamate + ATP + a [protein] C-terminal L-glutamate = ADP + hydrogenphosphate + H+ + a [protein] with C-terminal alpha-L-glutamate-alpha-L-glutamate.	got7fsn_ti												MetaCyc:RXN0-6726		molecular_function											owl:Class	
GO:0018169	biolink:NamedThing	ribosomal S6-glutamic acid ligase activity	Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6.	got7fsn_ti														molecular_function											owl:Class	
GO:0047848	biolink:NamedThing	dephospho-[reductase kinase] kinase activity	Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase].	got7fsn_ti	AMP-activated kinase activity|ATP:dephospho-{hydroxymethylglutaryl-CoA reductase (NADPH)kinase} phosphotransferase activity|AMP-activated protein kinase kinase activity|reductase kinase activity|STK30|reductase kinase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase kinase (phosphorylating) activity|dephospho-reductase kinase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase kinase activity											EC:2.7.11.3|MetaCyc:DEPHOSPHO-REDUCTASE-KINASE-KINASE-RXN		molecular_function											owl:Class	
GO:0039645	biolink:NamedThing	modulation by virus of host G1/S transition checkpoint	Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint.	got7fsn_ti	G1/S host cell cycle checkpoint dysregulation by virus						bf	2012-10-09T15:08:57Z				VZ:880		biological_process											owl:Class	
GO:0046927	biolink:NamedThing	peptidyl-threonine racemization	The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine.	got7fsn_ti														biological_process											owl:Class	
GO:1900509	biolink:NamedThing	regulation of pentose catabolic process to ethanol	Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol.	got7fsn_ti	regulation of pentose catabolism to ethanol						tt	2012-05-02T04:04:40Z						biological_process											owl:Class	
GO:0034088	biolink:NamedThing	maintenance of mitotic sister chromatid cohesion	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.	got7fsn_ti	mitotic cohesion stability													biological_process											owl:Class	
GO:0034086	biolink:NamedThing	maintenance of sister chromatid cohesion	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate.	got7fsn_ti														biological_process											owl:Class	
GO:0043727	biolink:NamedThing	5-amino-4-imidazole carboxylate lyase activity	Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate.	got7fsn_ti												EC:4.1.1.21		molecular_function											owl:Class	
GO:0016260	biolink:NamedThing	selenocysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins.	got7fsn_ti	selenocysteine synthesis|selenocysteine biosynthesis|selenocysteine anabolism|selenocysteine formation													biological_process											owl:Class	
GO:0080058	biolink:NamedThing	protein deglutathionylation	The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage.	got7fsn_ti	protein amino acid deglutathionylation						dhl	2009-04-13T02:48:06Z						biological_process											owl:Class	
GO:0097688	biolink:NamedThing	glutamate receptor clustering	The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane.	got7fsn_ti	glutamatergic receptor clustering						pr	2015-02-11T11:49:13Z						biological_process											owl:Class	
GO:1990005	biolink:NamedThing	granular vesicle	A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.	got7fsn_ti							pr	2012-12-11T14:51:48Z				NIF_Subcellular:sao478230652		cellular_component											owl:Class	
GO:0061561	biolink:NamedThing	trigeminal ganglion formation	The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti	trigeminal ganglia formation						dph	2013-07-10T09:08:13Z						biological_process											owl:Class	
GO:0070387	biolink:NamedThing	procollagen-proline 4-dioxygenase complex, alpha(II) type	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations.	got7fsn_ti	procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(II) type|prolyl 4-hydroxylase complex (alpha(II)-type)													cellular_component											owl:Class	
GO:0016499	biolink:NamedThing	orexin receptor activity	Combining with orexin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0010206	biolink:NamedThing	photosystem II repair	Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition.	got7fsn_ti														biological_process											owl:Class	
GO:0030091	biolink:NamedThing	protein repair	The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues.	got7fsn_ti														biological_process											owl:Class	
GO:0014723	biolink:NamedThing	regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril.	got7fsn_ti	regulation of calcium ion sensitivity of myofibril involved in skeletal muscle contraction													biological_process											owl:Class	
GO:0014722	biolink:NamedThing	regulation of skeletal muscle contraction by calcium ion signaling	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction.	got7fsn_ti	regulation of skeletal muscle contraction by calcium ion signalling													biological_process											owl:Class	
GO:0032807	biolink:NamedThing	DNA ligase IV complex	A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p.	got7fsn_ti	DNA ligase IV-XRCC4 complex													cellular_component											owl:Class	
GO:0071957	biolink:NamedThing	old mitotic spindle pole body	The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis.	got7fsn_ti	old SPB						mah	2011-06-01T02:32:10Z						cellular_component											owl:Class	
GO:0001181	biolink:NamedThing	RNA polymerase I general transcription initiation factor activity	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs.	got7fsn_ti	general RNA polymerase I transcription factor activity|transcription factor activity, core RNA polymerase I binding|RNA polymerase I transcription general initiation factor activity|core RNA polymerase I binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/14736					krc	2011-08-12T04:13:30Z						molecular_function											owl:Class	
GO:0045618	biolink:NamedThing	positive regulation of keratinocyte differentiation	Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.	got7fsn_ti	upregulation of keratinocyte differentiation|stimulation of keratinocyte differentiation|up-regulation of keratinocyte differentiation|activation of keratinocyte differentiation|up regulation of keratinocyte differentiation													biological_process											owl:Class	
GO:0003239	biolink:NamedThing	conus arteriosus morphogenesis	The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.	got7fsn_ti							dph	2009-10-13T11:25:04Z						biological_process											owl:Class	
GO:0021748	biolink:NamedThing	dorsal cochlear nucleus development	The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0140326	biolink:NamedThing	ATPase-coupled intramembrane lipid transporter activity	Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases.	got7fsn_ti	aminophospholipid-transporting ATPase|phospholipid-translocating ATPase activity|phospholipid flippase activity|phospholipid translocating ATPase activity|phospholipid-transporting ATPase activity|ATPase-coupled phospholipid transporter activity|ATPase-dependent phospholipid transporter activity	https://github.com/geneontology/go-ontology/issues/21612|https://github.com/geneontology/go-ontology/issues/17648					pg	2019-04-29T12:42:26Z			GO:0008557|GO:0004012	EC:7.6.2.1|Reactome:R-HSA-939763|Reactome:R-HSA-947591|MetaCyc:3.6.3.1-RXN		molecular_function											owl:Class	
GO:0000465	biolink:NamedThing	exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0061077	biolink:NamedThing	chaperone-mediated protein folding	The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.	got7fsn_ti							dph	2010-04-06T03:28:55Z						biological_process											owl:Class	
GO:0019661	biolink:NamedThing	glucose catabolic process to lactate via pyruvate	The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).	got7fsn_ti	glucose fermentation to lactate via pyruvate|homofermentative lactate fermentation|homolactic fermentation|homofermentative pathway|homofermentation|homolactate fermentation											MetaCyc:ANAEROFRUCAT-PWY		biological_process											owl:Class	
GO:0019659	biolink:NamedThing	glucose catabolic process to lactate	The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP).	got7fsn_ti	glucose fermentation to lactate|lactate fermentation											Wikipedia:Lactic_acid_fermentation		biological_process											owl:Class	
GO:0004958	biolink:NamedThing	prostaglandin F receptor activity	Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity.	got7fsn_ti	PGF receptor activity|PGF(2-alpha) receptor activity													molecular_function											owl:Class	
GO:0044615	biolink:NamedThing	nuclear pore nuclear basket	A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.	got7fsn_ti							jl	2012-06-20T01:31:01Z						cellular_component											owl:Class	
GO:0070859	biolink:NamedThing	positive regulation of bile acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.	got7fsn_ti	upregulation of bile acid biosynthetic process|up regulation of bile acid biosynthetic process|positive regulation of bile acid synthesis|positive regulation of bile acid formation|activation of bile acid biosynthetic process|up-regulation of bile acid biosynthetic process|positive regulation of bile acid anabolism|stimulation of bile acid biosynthetic process|positive regulation of bile acid biosynthesis						mah	2009-08-14T03:22:58Z						biological_process											owl:Class	
GO:0010893	biolink:NamedThing	positive regulation of steroid biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	got7fsn_ti														biological_process											owl:Class	
GO:0044028	biolink:NamedThing	DNA hypomethylation	An decrease in the epigenetic methylation of cytosine and adenosine residues in DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0044030	biolink:NamedThing	regulation of DNA methylation	Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.	got7fsn_ti														biological_process											owl:Class	
GO:0033833	biolink:NamedThing	hydroxymethylfurfural reductase (NADH) activity	Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.	got7fsn_ti												MetaCyc:RXN-10738		molecular_function											owl:Class	
GO:0004781	biolink:NamedThing	sulfate adenylyltransferase (ATP) activity	Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.	got7fsn_ti	adenosine-5'-triphosphate sulfurylase activity|sulphate adenylyltransferase (ATP) activity|adenosinetriphosphate sulfurylase activity|sulfurylase activity|ATP sulfurylase activity|sulfate adenylate transferase activity|ATP:sulfate adenylyltransferase activity|ATP-sulfurylase activity|adenylylsulfate pyrophosphorylase activity											EC:2.7.7.4|RHEA:18133|Reactome:R-HSA-174392|MetaCyc:SULFATE-ADENYLYLTRANS-RXN|Reactome:R-HSA-3560794		molecular_function											owl:Class	
GO:0010575	biolink:NamedThing	positive regulation of vascular endothelial growth factor production	Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.	got7fsn_ti														biological_process											owl:Class	
GO:0071707	biolink:NamedThing	immunoglobulin heavy chain V-D-J recombination	The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).	got7fsn_ti	immunoglobulin V(D)J recombination|immunoglobulin V-D-J joining|immunoglobulin V(D)J joining						mah	2010-03-09T04:20:31Z						biological_process											owl:Class	
GO:0034530	biolink:NamedThing	4-hydroxymethylsalicyaldehyde dehydrogenase activity	Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+.	got7fsn_ti												UM-BBD_reactionID:r0767|EC:1.2.1.-		molecular_function											owl:Class	
GO:0008184	biolink:NamedThing	glycogen phosphorylase activity	Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.	got7fsn_ti												Reactome:R-HSA-453339|Reactome:R-HSA-71515|MetaCyc:GLYCOPHOSPHORYL-RXN|Reactome:R-HSA-71590|Reactome:R-HSA-453358		molecular_function											owl:Class	
GO:0035272	biolink:NamedThing	exocrine system development	Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.	got7fsn_ti														biological_process											owl:Class	
GO:0005117	biolink:NamedThing	wishful thinking binding	Binding to wishful thinking (Wit), a type II bone morphogenic protein receptor.	got7fsn_ti	wishful thinking ligand|Wit binding|Wit ligand|SE20 receptor binding													molecular_function											owl:Class	
GO:0047512	biolink:NamedThing	(S,S)-butanediol dehydrogenase activity	Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD(+) = acetoin + H(+) + NADH.	got7fsn_ti	L-BDH|L(+)-2,3-butanediol dehydrogenase (L-acetoin forming)|(S,S)-butane-2,3-diol:NAD+ oxidoreductase activity|L-butanediol dehydrogenase activity											EC:1.1.1.76|MetaCyc:SS-BUTANEDIOL-DEHYDROGENASE-RXN|RHEA:12184|KEGG_REACTION:R03707		molecular_function											owl:Class	
GO:0036266	biolink:NamedThing	Cdc48p-Npl4p-Vms1p AAA ATPase complex	A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p.	got7fsn_ti	Cdc48p-Npl4p-Vms1p complex|Vms1-Cdc48-Npl4 complex|Vms1p-Cdc48p-Npl4p complex						bf	2012-06-29T10:57:48Z						cellular_component											owl:Class	
GO:0061715	biolink:NamedThing	miRNA 2'-O-methylation	The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an miRNA molecule.	got7fsn_ti							dph	2015-06-29T08:41:03Z						biological_process											owl:Class	
GO:0062035	biolink:NamedThing	sensory perception of cold stimulus	The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.	got7fsn_ti							dph	2018-04-30T13:48:10Z						biological_process											owl:Class	
GO:0004747	biolink:NamedThing	ribokinase activity	Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate.	got7fsn_ti	ATP:D-ribose 5-phosphotransferase activity|ribokinase (phosphorylating)|deoxyribokinase activity|D-ribokinase activity											EC:2.7.1.15|MetaCyc:RIBOKIN-RXN|Reactome:R-HSA-8955844|RHEA:13697		molecular_function											owl:Class	
GO:0051285	biolink:NamedThing	cell cortex of cell tip	The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.	got7fsn_ti	cell cortex of cell end													cellular_component											owl:Class	
GO:0103068	biolink:NamedThing	leukotriene C4 gamma-glutamyl transferase activity	Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma-L-glutamyl)-L-amino acid.	got7fsn_ti												MetaCyc:RXN66-336|EC:2.3.2.2		molecular_function											owl:Class	
GO:0052681	biolink:NamedThing	alpha-bisabolene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate.	got7fsn_ti	bisabolene synthase activity|(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-alpha-bisabolene-forming] activity											KEGG_REACTION:R08370|EC:4.2.3.38|MetaCyc:RXN-8550|RHEA:25436		molecular_function											owl:Class	
GO:1902102	biolink:NamedThing	regulation of metaphase/anaphase transition of meiotic cell cycle	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.	got7fsn_ti	regulation of meiotic metaphase/anaphase transition						jl	2013-05-02T12:45:38Z						biological_process											owl:Class	
GO:1905132	biolink:NamedThing	regulation of meiotic chromosome separation	Any process that modulates the frequency, rate or extent of meiotic chromosome separation.	got7fsn_ti	regulation of chromosome separation during meiosis|regulation of meiotic chromosome resolution						dph	2016-04-12T17:46:29Z						biological_process											owl:Class	
GO:0032492	biolink:NamedThing	detection of molecule of oomycetes origin	The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal.	got7fsn_ti	detection of oomycetes associated molecule													biological_process											owl:Class	
GO:0003227	biolink:NamedThing	right ventricular trabecular myocardium morphogenesis	The process in which the anatomical structures of the right ventricular myocardium are generated and organized.	got7fsn_ti							dph	2009-10-13T10:50:59Z						biological_process											owl:Class	
GO:0033116	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment membrane	The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.	got7fsn_ti	ER-Golgi intermediate compartment membrane													cellular_component											owl:Class	
GO:0002132	biolink:NamedThing	wobble position uridine ribose methylation	The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.	got7fsn_ti														biological_process											owl:Class	
GO:0101016	biolink:NamedThing	FMN-binding domain binding	Binding to the FMN-binding domain of a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0075293	biolink:NamedThing	response to host pH environment	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response of symbiont to host pH environment													biological_process											owl:Class	
GO:0047781	biolink:NamedThing	citrullinase activity	Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine.	got7fsn_ti	L-citrulline N5-carbamoyldihydrolase activity|citrulline ureidase activity|L-citrulline 5-N-carbamoyldihydrolase activity|citrulline hydrolase activity											MetaCyc:CITRULLINASE-RXN|EC:3.5.1.20|RHEA:11940		molecular_function											owl:Class	
GO:0034790	biolink:NamedThing	3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity	Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1043		molecular_function											owl:Class	
GO:0047795	biolink:NamedThing	cyclohexane-1,2-diol dehydrogenase activity	Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH.	got7fsn_ti	trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase activity											MetaCyc:CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN|EC:1.1.1.174|RHEA:18141		molecular_function											owl:Class	
GO:1990083	biolink:NamedThing	DnaA-Hda complex	A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda.	got7fsn_ti							bhm	2013-04-30T11:49:04Z						cellular_component											owl:Class	
GO:0008470	biolink:NamedThing	isovaleryl-CoA dehydrogenase activity	Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF.	got7fsn_ti	isovaleroyl-coenzyme A dehydrogenase activity|3-methylbutanoyl-CoA:(acceptor) oxidoreductase activity|3-methylbutanoyl-CoA:acceptor oxidoreductase activity|isovaleryl-coenzyme A dehydrogenase activity											MetaCyc:ISOVALERYL-COA-FAD-RXN|Reactome:R-HSA-70745|RHEA:12276|EC:1.3.8.4		molecular_function											owl:Class	
GO:0006420	biolink:NamedThing	arginyl-tRNA aminoacylation	The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA.  The  2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0044840	biolink:NamedThing	gut granule	A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage.	got7fsn_ti							jl	2014-03-25T11:56:41Z						cellular_component											owl:Class	
GO:0072201	biolink:NamedThing	negative regulation of mesenchymal cell proliferation	Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	got7fsn_ti							mah	2010-03-01T03:43:29Z						biological_process											owl:Class	
GO:0035820	biolink:NamedThing	negative regulation of renal sodium excretion by angiotensin	The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time.	got7fsn_ti							bf	2011-04-20T02:10:50Z						biological_process											owl:Class	
GO:0004794	biolink:NamedThing	L-threonine ammonia-lyase activity	Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3.	got7fsn_ti	L-threonine hydro-lyase (deaminating) activity|L-threonine deaminase activity|L-threonine ammonia-lyase (2-oxobutanoate-forming)|threonine dehydrase activity|L-serine dehydratase activity|threonine dehydratase activity|L-threonine dehydratase activity|threonine deaminase activity|threonine ammonia-lyase activity|serine deaminase activity				Note that this function was formerly EC:4.2.1.16.							RHEA:22108|EC:4.3.1.19|UM-BBD_reactionID:r0433|MetaCyc:THREDEHYD-RXN		molecular_function											owl:Class	
GO:0004069	biolink:NamedThing	L-aspartate:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.	got7fsn_ti	aspartyl aminotransferase activity|aspartate:2-oxoglutarate aminotransferase activity|glutamic oxalic transaminase activity|aspartic acid aminotransferase activity|glutamic--aspartic transaminase activity|aspartic aminotransferase activity|L-aspartate-2-oxoglutarate aminotransferase activity|oxaloacetate-aspartate aminotransferase activity|AspT|L-aspartate transaminase activity|2-oxoglutarate-glutamate aminotransferase activity|aspartate-2-oxoglutarate transaminase activity|AAT|L-aspartate-2-oxoglutarate-transaminase activity|L-aspartic aminotransferase activity|glutamic--oxaloacetic transaminase activity|glutamic-oxalacetic transaminase activity|transaminase A activity|oxaloacetate transferase activity|L-aspartate-2-ketoglutarate aminotransferase activity|glutamate-oxalate transaminase activity|glutamic-aspartic aminotransferase activity|glutamate oxaloacetate transaminase activity|glutamate-oxalacetate aminotransferase activity|L-aspartate-alpha-ketoglutarate transaminase activity|aspartate transaminase activity|aspartate aminotransferase activity|GOT (enzyme)|aspartate alpha-ketoglutarate transaminase activity											RHEA:21824|Reactome:R-HSA-70581|Reactome:R-HSA-70613|KEGG_REACTION:R00355|Reactome:R-HSA-70592|EC:2.6.1.1|Reactome:R-HSA-70596|MetaCyc:ASPAMINOTRANS-RXN		molecular_function											owl:Class	
GO:0032496	biolink:NamedThing	response to lipopolysaccharide	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.	got7fsn_ti	response to endotoxin|response to LPS													biological_process											owl:Class	
GO:0086074	biolink:NamedThing	Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication	The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	got7fsn_ti							dph	2011-11-22T10:02:24Z						biological_process											owl:Class	
GO:0009300	biolink:NamedThing	antisense RNA transcription	The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0022869	biolink:NamedThing	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	lactose PTS transporter activity													molecular_function											owl:Class	
GO:0015155	biolink:NamedThing	lactose transmembrane transporter activity	Enables the transfer of lactose from one side of a membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.	got7fsn_ti	lactose/glucose efflux transporter activity|lactose permease activity										GO:0019189			molecular_function											owl:Class	
GO:0004577	biolink:NamedThing	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol.	got7fsn_ti	N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity|UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity|uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity											MetaCyc:2.4.1.141-RXN|EC:2.4.1.141|Reactome:R-HSA-446207|RHEA:23380|Reactome:R-HSA-5633241		molecular_function											owl:Class	
GO:0140272	biolink:NamedThing	exogenous protein binding	Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein.	got7fsn_ti					Note that as GO captures normal processes, it may be that exogenous proteins interactions are normal for one of the participating species but not the other. Therefore reciprocal annotations should not be made without confirming that it is physiological relevant.		pg	2018-10-01T10:03:21Z						molecular_function											owl:Class	
GO:0005608	biolink:NamedThing	laminin-3 complex	A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.	got7fsn_ti	laminin-121 complex													cellular_component											owl:Class	
GO:0070522	biolink:NamedThing	ERCC4-ERCC1 complex	A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.	got7fsn_ti	Rad1-Rad10 complex|XPF-ERCC1 complex				Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.									cellular_component											owl:Class	
GO:1990269	biolink:NamedThing	RNA polymerase II C-terminal domain phosphoserine binding	Binding to phosphorylated serine residues in the C-terminal domain of RNA polymerase II.	got7fsn_ti	RNAP II C-terminal domain phosphoserine binding|RNA Pol II C-terminal domain phosphoserine binding						tb	2014-01-11T00:34:59Z						molecular_function											owl:Class	
GO:0050815	biolink:NamedThing	phosphoserine residue binding	Binding to a phosphorylated serine residue within a protein.	got7fsn_ti	phosphoserine binding													molecular_function											owl:Class	
GO:0047465	biolink:NamedThing	N-acylglucosamine-6-phosphate 2-epimerase activity	Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate.	got7fsn_ti	N-acetylmannosamine-6-phosphate 2-epimerase activity|N-acyl-D-glucosamine-6-phosphate 2-epimerase activity|acylglucosamine-6-phosphate 2-epimerase activity|N-acetylglucosmamine 6-phosphate 2-epimerase activity|acylmannosamine phosphate 2-epimerase activity|acylglucosamine phosphate 2-epimerase activity											RHEA:23932|EC:5.1.3.9|MetaCyc:5.1.3.9-RXN		molecular_function											owl:Class	
GO:0002236	biolink:NamedThing	detection of misfolded protein	The series of events in which a misfolded protein stimulus is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0036020	biolink:NamedThing	endolysosome membrane	The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.	got7fsn_ti	endolysosomal membrane						bf	2011-10-13T04:32:00Z						cellular_component											owl:Class	
GO:0002154	biolink:NamedThing	thyroid hormone mediated signaling pathway	A series of molecular signals mediated by the detection of a thyroid hormone.	got7fsn_ti	thyroid hormone mediated signalling pathway						hjd	2009-11-19T12:36:29Z						biological_process											owl:Class	
GO:0034204	biolink:NamedThing	lipid translocation	The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	got7fsn_ti	intramembrane lipid transfer													biological_process											owl:Class	
GO:0103060	biolink:NamedThing	kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP.	got7fsn_ti												MetaCyc:RXN1F-475		molecular_function											owl:Class	
GO:0010904	biolink:NamedThing	regulation of UDP-glucose catabolic process	Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	regulation of UDP-glucose catabolism													biological_process											owl:Class	
GO:0043558	biolink:NamedThing	regulation of translational initiation in response to stress	Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress.	got7fsn_ti	regulation of translation initiation in response to stress													biological_process											owl:Class	
GO:0102287	biolink:NamedThing	4-coumaroylhexanoylmethane synthase activity	Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O <=> 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-12668		molecular_function											owl:Class	
GO:0031822	biolink:NamedThing	type 1B serotonin receptor binding	Binding to a type 1B serotonin receptor.	got7fsn_ti	type 1B serotonin receptor ligand|5-hydroxytryptamine 1B receptor binding													molecular_function											owl:Class	
GO:0047949	biolink:NamedThing	glutarate-semialdehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH.	got7fsn_ti	glutarate semialdehyde dehydrogenase (NAD+) activity|glutarate-semialdehyde:NAD+ oxidoreductase activity											RHEA:12064|EC:1.2.1.20|MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0140490	biolink:NamedThing	microtubule nucleator activity	The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly.	got7fsn_ti	microtubule nucleation template activity	https://github.com/geneontology/go-ontology/issues/19709					pg	2020-07-01T08:47:54Z						molecular_function											owl:Class	
GO:1990177	biolink:NamedThing	IHF-DNA complex	A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid.	got7fsn_ti	IHFa-IHFb-DNA complex|IHF complex						bhm	2013-08-30T12:22:54Z						cellular_component											owl:Class	
GO:0102185	biolink:NamedThing	4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + 2 H2O.	got7fsn_ti												MetaCyc:RXN-11947		molecular_function											owl:Class	
GO:0043008	biolink:NamedThing	ATP-dependent protein binding	Binding to a protein or protein complex using energy from ATP hydrolysis.	got7fsn_ti														molecular_function											owl:Class	
GO:0045894	biolink:NamedThing	negative regulation of mating-type specific transcription, DNA-templated	Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription.	got7fsn_ti	inhibition of transcription, mating-type specific|down regulation of transcription, mating-type specific|downregulation of transcription, mating-type specific|down-regulation of transcription, mating-type specific|negative regulation of mating-type specific transcription, DNA-dependent													biological_process											owl:Class	
GO:0061520	biolink:NamedThing	Langerhans cell differentiation	The process in which a precursor cell type acquires the specialized features of a Langerhans cell.	got7fsn_ti							dph	2013-04-18T13:29:07Z						biological_process											owl:Class	
GO:0030669	biolink:NamedThing	clathrin-coated endocytic vesicle membrane	The lipid bilayer surrounding a clathrin-coated endocytic vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0061345	biolink:NamedThing	planar cell polarity pathway involved in cardiac muscle cell fate commitment	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.	got7fsn_ti							dph	2010-09-30T12:39:05Z						biological_process											owl:Class	
GO:0004087	biolink:NamedThing	carbamoyl-phosphate synthase (ammonia) activity	Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate.	got7fsn_ti	carbamylphosphate synthetase I|carbon-dioxide--ammonia ligase activity|carbamylphosphate synthetase activity|carbamoyl-phosphate synthetase (ammonia) activity|carbamoylphosphate synthetase (ammonia) activity|carbamoyl phosphate synthase (ammonia) activity|carbamoylphosphate synthase activity|carbamoyl-phosphate synthetase I activity|carbamoylphosphate synthase (ammonia)|carbmoylphosphate synthetase activity|carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)|CPS I activity											EC:6.3.4.16|MetaCyc:6.3.4.16-RXN|Reactome:R-HSA-70555|RHEA:10624|KEGG_REACTION:R00149		molecular_function											owl:Class	
GO:0030265	biolink:NamedThing	phospholipase C-activating rhodopsin mediated signaling pathway	The series of molecular signals generated as a consequence of a rhodopsin molecule being activated by a photon, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	rhodopsin mediated G-protein signalling, coupled to IP3 second messenger|rhodopsin mediated G protein signalling, coupled to IP3 second messenger|rhodopsin mediated G protein signaling, coupled to IP3 second messenger|rhodopsin mediated G-protein signaling, coupled to IP3 second messenger|phospholipase C-activating rhodopsin mediated G-protein coupled receptor signaling pathway|PLC-activating rhodopsin mediated signaling pathway													biological_process											owl:Class	
GO:1904967	biolink:NamedThing	regulation of monopolar spindle attachment to meiosis I kinetochore	Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.	got7fsn_ti	regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|regulation of monopolar attachment|regulation of sister kinetochore mono-orientation|correction of merotelic kinetochore attachment, meiosis I|regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|regulation of attachment of spindle microtubules to kinetochore during meiosis I|repair of merotelic kinetochore attachment defect, meiosis I	https://github.com/geneontology/go-ontology/issues/18815					mah	2016-02-15T15:19:12Z			GO:0090699			biological_process											owl:Class	
GO:0140274	biolink:NamedThing	repair of kinetochore microtubule attachment defect	The cell cycle process where kinetochore microtubule attachment defects are corrected.	got7fsn_ti	correction of kinetochore microtubule attachment defects|repair of kinetochore microtubule attachment defects						pg	2018-10-01T11:30:19Z						biological_process											owl:Class	
GO:0047885	biolink:NamedThing	farnesol 2-isomerase activity	Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.	got7fsn_ti	2-trans,6-trans-farnesol 2-cis-trans-isomerase activity|farnesol isomerase activity											MetaCyc:FARNESOL-2-ISOMERASE-RXN|EC:5.2.1.9|KEGG_REACTION:R03265|RHEA:13401		molecular_function											owl:Class	
GO:0070984	biolink:NamedThing	SET domain binding	Binding to a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.	got7fsn_ti	SET binding						mah	2009-10-27T04:09:28Z						molecular_function											owl:Class	
GO:0003881	biolink:NamedThing	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity	Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H(+).	got7fsn_ti	CDP diglyceride-inositol phosphatidyltransferase activity|phosphatidylinositol synthase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase activity|CDP-diacylglycerol--inositol phosphatidyltransferase activity|CDPdiacylglycerol-inositol 3-phosphatidyltransferase activity|CDP-DG:inositol transferase activity|CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase activity|CDP-diglyceride:inositol transferase activity|CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase activity|cytidine diphosphoglyceride-inositol transferase activity|cytidine diphosphodiglyceride-inositol phosphatidyltransferase activity|CDP-diglyceride-inositol transferase activity|cytidine diphosphoglyceride-inositol phosphatidyltransferase activity											RHEA:11580|KEGG_REACTION:R01802|MetaCyc:2.7.8.11-RXN|EC:2.7.8.11|Reactome:R-HSA-1482976		molecular_function											owl:Class	
GO:0047595	biolink:NamedThing	6-hydroxynicotinate reductase activity	Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin.	got7fsn_ti	6-oxotetrahydronicotinate dehydrogenase activity|1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase activity|6-hydroxynicotinic reductase activity|6-oxotetrahydro-nicotinate dehydrogenase activity|6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase activity|HNA reductase activity											EC:1.3.7.1|RHEA:17225|MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0106063	biolink:NamedThing	G protein-coupled folate receptor activity	Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.	got7fsn_ti	G-protein coupled folate receptor activity|G-protein coupled folic acid receptor activity						hjd	2017-10-27T17:10:07Z						molecular_function											owl:Class	
GO:1902686	biolink:NamedThing	mitochondrial outer membrane permeabilization involved in programmed cell death	The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process.	got7fsn_ti	positive regulation of mitochondrial membrane permeability involved in nonapoptotic programmed cell death|mitochondrial membrane permeabilization involved in non-apoptotic programmed cell death|mitochondrial membrane permeability transition involved in regulated cell death|MPT involved in caspase-independent apoptosis|positive regulation of mitochondrial membrane permeability involved in PCD|mitochondrial membrane permeabilization involved in programmed cell death|MPT involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in regulated cell death|positive regulation of transport across mitochondrial membrane involved in programmed cell death|mitochondrial membrane permeability transition involved in nonapoptotic programmed cell death|MPT involved in regulated cell death|mitochondrial membrane permeabilization involved in caspase-independent apoptosis|positive regulation of transport across mitochondrial membrane involved in caspase-independent apoptosis|mitochondrial permeability transition involved in non-apoptotic programmed cell death|MPT involved in PCD|MPT involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in caspase-independent apoptosis|mitochondrial membrane permeability transition involved in caspase-independent cell death|mitochondrial permeability transition involved in PCD|MPT involved in caspase-independent cell death|mitochondrion outer membrane permeabilization involved in programmed cell death|mitochondrial membrane permeabilization involved in PCD|mitochondrial membrane permeabilization involved in caspase-independent cell death|mitochondrial membrane permeability transition involved in programmed cell death|positive regulation of mitochondrial membrane permeability involved in regulated cell death|positive regulation of mitochondrial membrane permeability involved in non-apoptotic programmed cell death|mitochondrial membrane permeability transition involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in nonapoptotic programmed cell death|mitochondrial permeability transition involved in caspase-independent cell death|mitochondrial outer membrane permeabilization during programmed cell death|positive regulation of mitochondrial membrane permeability involved in caspase-independent apoptosis|positive regulation of transport across mitochondrial membrane involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in PCD|positive regulation of transport across mitochondrial membrane involved in caspase-independent cell death|mitochondrial membrane permeabilization involved in nonapoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in PCD|mitochondrial permeability transition involved in caspase-independent apoptosis|positive regulation of mitochondrial membrane permeability involved in caspase-independent cell death|positive regulation of transport across mitochondrial membrane involved in regulated cell death|mitochondrial permeability transition involved in programmed cell death|positive regulation of mitochondrial membrane permeability involved in programmed cell death|MPT involved in programmed cell death|mitochondrial membrane permeabilization involved in regulated cell death|positive regulation of transport across mitochondrial membrane involved in non-apoptotic programmed cell death						pr	2014-02-10T12:56:34Z						biological_process											owl:Class	
GO:0102423	biolink:NamedThing	(+)-sesaminol 2-O-glucosyltransferase activity	Catalysis of the reaction: (+)-sesaminol + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13818		molecular_function											owl:Class	
GO:0070409	biolink:NamedThing	carbamoyl phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.	got7fsn_ti	carbamoyl phosphate anabolism|carbamoyl phosphate formation|carbamyl phosphate biosynthetic process|carbamoyl phosphate biosynthesis|carbamoyl phosphate synthesis													biological_process											owl:Class	
GO:0061598	biolink:NamedThing	molybdopterin adenylyltransferase activity	Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.	got7fsn_ti							dph	2014-02-10T14:14:06Z				RHEA:31331|EC:2.7.7.75		molecular_function											owl:Class	
GO:0002152	biolink:NamedThing	bile acid conjugation	The process in which bile acids are covalently linked to taurine or glycine.	got7fsn_ti					The bile acid is first activated using CoA by cholate-CoA ligase activity(GO:0047747), then conjugated to taurine or glycine by glycine N-choloyltransferase activity (GO:0047963; appears to use either glycine or taurine).		hjd	2009-10-29T01:41:51Z						biological_process											owl:Class	
GO:1990833	biolink:NamedThing	clathrin-uncoating ATPase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the removal of clathrin from vesicle membranes, coupled to the hydrolysis of ATP.	got7fsn_ti							sl	2015-08-21T18:01:42Z						molecular_function											owl:Class	
GO:1900565	biolink:NamedThing	chanoclavine-I catabolic process	The chemical reactions and pathways resulting in the breakdown of chanoclavine-I.	got7fsn_ti	chanoclavine-I breakdown|chanoclavine-I catabolism|chanoclavine-I degradation						di	2012-05-15T06:30:48Z						biological_process											owl:Class	
GO:0050627	biolink:NamedThing	mycothione reductase activity	Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione.	got7fsn_ti	mycothiol-disulfide reductase activity|mycothiol:NAD(P)+ oxidoreductase activity											MetaCyc:1.8.1.15-RXN|EC:1.8.1.15		molecular_function											owl:Class	
GO:0009647	biolink:NamedThing	skotomorphogenesis	The control of plant growth, development, and differentiation in response to growth in darkness.	got7fsn_ti	etiolation													biological_process											owl:Class	
GO:0090499	biolink:NamedThing	pimelyl-[acyl-carrier protein] methyl ester esterase activity	Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol.	got7fsn_ti	pimelyl-[acyl-carrier protein] methyl ester hydrolase activity				Note that while this reaction occurs on a modified protein (acyl-carrier protein), the ACP only acts as a carrier that later releases the end product.		tb	2012-10-19T12:10:01Z						molecular_function											owl:Class	
GO:1990827	biolink:NamedThing	deaminase binding	Binding to an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3).	got7fsn_ti							sl	2015-08-19T23:48:32Z						molecular_function											owl:Class	
GO:0086026	biolink:NamedThing	atrial cardiac muscle cell to AV node cell signaling	Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell.	got7fsn_ti	atrial cardiomyocyte to atrioventricular node cell signaling|atrial cardiomyocyte to AV node cell signalling|atrial cardiomyocyte to AV node cell signaling						tb	2011-11-11T02:02:14Z						biological_process											owl:Class	
GO:0031428	biolink:NamedThing	box C/D RNP complex	A ribonucleoprotein complex containing a box C/D type RNA that can carry out ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya.	got7fsn_ti	box C/D small nucleolar ribonucleoprotein complex|box C/D snoRNP ribose-2'-O-methyltransferase complex|box C/D snoRNP ribose 2'-O methylase complex|box C/D sRNP complex|box C/D snoRNP complex	https://github.com/geneontology/go-ontology/issues/20416												cellular_component											owl:Class	
GO:0005732	biolink:NamedThing	sno(s)RNA-containing ribonucleoprotein complex	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA.	got7fsn_ti	small ribonucleoprotein|snoRNP|small nucleolar ribonucleoprotein complex|sRNP|small ribonucleoprotein protein complex|small nucleolar ribonucleoprotein	https://github.com/geneontology/go-ontology/issues/20416			Note that 'nucleolar' in the name acronym 'snoRNA' is part of the RNA family designation 'small nucleolar', and does not reflect the location of the complex. Both box C/D type and box H/ACA RNAs are found in Archaea (where they are referred to as sRNAs) as well as in Eukaryota. In eukaryotes, box H/ACA RNAs are found in both nucleolar-localized snoRNP complexes and in Cajal body-localized scaRNP complexes.									cellular_component											owl:Class	
GO:0036417	biolink:NamedThing	tRNA destabilization	Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes.	got7fsn_ti							bf	2013-08-22T15:43:13Z						biological_process											owl:Class	
GO:0030474	biolink:NamedThing	spindle pole body duplication	Construction of a new spindle pole body.	got7fsn_ti	spindle pole body assembly|spindle pole body replication|spindle pole body formation|spindle pole body duplication associated with nuclear envelope|spindle pole body duplication in cytoplasm|spindle pole body biosynthesis|spindle pole body biogenesis										GO:0031046|GO:0007103			biological_process											owl:Class	
GO:0097263	biolink:NamedThing	eoxin E4 synthase activity	Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.	got7fsn_ti							pr	2012-03-08T03:02:48Z				Reactome:R-HSA-2161868		molecular_function											owl:Class	
GO:0035684	biolink:NamedThing	helper T cell extravasation	The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.	got7fsn_ti	helper T-cell extravasation|T-helper cell extravasation						bf	2011-02-23T01:11:05Z						biological_process											owl:Class	
GO:0052811	biolink:NamedThing	1-phosphatidylinositol-3-phosphate 4-kinase activity	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+).	got7fsn_ti	phosphatidylinositol 3-phosphate 4-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 4-phosphotransferase activity						ai	2011-10-21T03:47:58Z				RHEA:63688|Reactome:R-HSA-1676145		molecular_function											owl:Class	
GO:0140328	biolink:NamedThing	floppase activity	Catalysis of the movement of a lipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	floppase activity (cytosolic to exoplasmic leaftlet)				Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the cytosolic to the exoplasmic leaftlet of a membrane).		pg	2019-04-29T12:58:53Z						molecular_function											owl:Class	
GO:0140594	biolink:NamedThing	xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity	Stops, prevents or reduces the activity of xyloglucan-specific endo-beta-1,4-glucanase.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20814					pg	2021-02-09T18:59:49Z						molecular_function											owl:Class	
GO:0102004	biolink:NamedThing	2-octaprenyl-6-hydroxyphenol methylase activity	Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:2-OCTAPRENYL-6-OHPHENOL-METHY-RXN|RHEA:27770		molecular_function											owl:Class	
GO:0033607	biolink:NamedThing	SOD1-Bcl-2 complex	A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway.	got7fsn_ti														cellular_component											owl:Class	
GO:0010541	biolink:NamedThing	acropetal auxin transport	The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root.	got7fsn_ti														biological_process											owl:Class	
GO:0102368	biolink:NamedThing	beta-amyrin 30-monooxygenase activity	Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 <=> 30-hydroxy-beta-amyrin + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-13489		molecular_function											owl:Class	
GO:0052684	biolink:NamedThing	L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity	Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O.	got7fsn_ti	L-serine hydro-lyase (adding indole; L-tryptophan-forming) activity|tryptophan synthase beta subunit activity											EC:4.2.1.122|KEGG_REACTION:R00674|MetaCyc:RXN0-2382|RHEA:26434		molecular_function											owl:Class	
GO:0032028	biolink:NamedThing	myosin head/neck binding	Binding to the head/neck region of a myosin heavy chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0034353	biolink:NamedThing	RNA pyrophosphohydrolase activity	Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end.	got7fsn_ti														molecular_function											owl:Class	
GO:0060819	biolink:NamedThing	inactivation of X chromosome by genetic imprinting	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genetic imprinting.	got7fsn_ti							dph	2009-08-11T10:56:06Z						biological_process											owl:Class	
GO:0004920	biolink:NamedThing	interleukin-10 receptor activity	Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-10 receptor activity|IL-10R													molecular_function											owl:Class	
GO:0045582	biolink:NamedThing	positive regulation of T cell differentiation	Any process that activates or increases the frequency, rate or extent of T cell differentiation.	got7fsn_ti	positive regulation of T-lymphocyte differentiation|up-regulation of T cell differentiation|up regulation of T cell differentiation|activation of T cell differentiation|positive regulation of T lymphocyte differentiation|positive regulation of T-cell differentiation|stimulation of T cell differentiation|positive regulation of T cell development|upregulation of T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0006607	biolink:NamedThing	NLS-bearing protein import into nucleus	The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope.	got7fsn_ti	NLS-bearing substrate import into nucleus|NLS-bearing substrate import into cell nucleus|NLS-bearing substrate-nucleus import|NLS-bearing substrate transport from cytoplasm to nucleus													biological_process											owl:Class	
GO:0046487	biolink:NamedThing	glyoxylate metabolic process	The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.	got7fsn_ti	glyoxylate metabolism													biological_process											owl:Class	
GO:0046553	biolink:NamedThing	D-malate dehydrogenase (decarboxylating) activity	Catalysis of the reaction: (R)-malate + NAD(+) = CO(2) + NADH + pyruvate.	got7fsn_ti	(R)-malate:NAD+ oxidoreductase (decarboxylating)|D-malic enzyme|bifunctional L(+)-tartrate dehydrogenase-D(+)-malate (decarboxylating)|D-malate dehydrogenase activity											MetaCyc:1.1.1.83-RXN|EC:1.1.1.83|RHEA:18365|KEGG_REACTION:R00215		molecular_function											owl:Class	
GO:0050135	biolink:NamedThing	NAD(P)+ nucleosidase activity	Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide.	got7fsn_ti	NAD(P) nucleosidase activity|nicotinamide adenine dinucleotide (phosphate) glycohydrolase activity|triphosphopyridine nucleotidase activity|NAD(P)(+) nucleosidase activity|nicotinamide adenine dinucleotide (phosphate) nucleosidase activity|NAD(P)+ glycohydrolase activity|NAD(P)ase activity											EC:3.2.2.6|MetaCyc:NADP+-NUCLEOSIDASE-RXN		molecular_function											owl:Class	
GO:0102455	biolink:NamedThing	anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside.	got7fsn_ti												MetaCyc:RXN-13965|RHEA:35419|EC:2.4.1.297		molecular_function											owl:Class	
GO:0061300	biolink:NamedThing	cerebellum vasculature development	The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-09-06T03:36:40Z						biological_process											owl:Class	
GO:0001944	biolink:NamedThing	vasculature development	The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.	got7fsn_ti	vascular system development													biological_process											owl:Class	
GO:0031388	biolink:NamedThing	organic acid phosphorylation	The process of introducing one or more phosphate groups into an organic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0032641	biolink:NamedThing	lymphotoxin A production	The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.	got7fsn_ti	lymphotoxin A formation|lymphotoxin A biosynthetic process|LTA production|lymphotoxin-alpha production|lymphotoxin A synthesis|tumor necrosis factor-beta production|TNF-B production|TNF-beta production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0042109			biological_process											owl:Class	
GO:0031604	biolink:NamedThing	nuclear proteasome core complex, alpha-subunit complex	The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0005680	biolink:NamedThing	anaphase-promoting complex	A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.	got7fsn_ti	cyclosome|anaphase promoting complex|APC				Note that the synonym 'APC' should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein.							Wikipedia:Anaphase-promoting_complex		cellular_component											owl:Class	
GO:0036341	biolink:NamedThing	chitin-based cuticle sclerotization by protein cross-linking	The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle.	got7fsn_ti	chitin-based cuticle sclerotization by protein cross-linking and cuticle tanning						bf	2012-09-11T13:51:46Z						biological_process											owl:Class	
GO:0110127	biolink:NamedThing	phloem unloading	The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.	got7fsn_ti							kmv	2018-09-07T21:33:07Z						biological_process											owl:Class	
GO:0035343	biolink:NamedThing	negative regulation of inosine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	negative regulation of hypoxanthine riboside transport						bf	2010-03-04T10:06:07Z						biological_process											owl:Class	
GO:0060970	biolink:NamedThing	embryonic heart tube dorsal/ventral pattern formation	The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis.	got7fsn_ti							dph	2009-10-06T10:14:53Z						biological_process											owl:Class	
GO:0047881	biolink:NamedThing	estradiol 17-alpha-dehydrogenase activity	Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+.	got7fsn_ti	17alpha-hydroxy steroid dehydrogenase activity|estradiol 17alpha-dehydrogenase activity|estradiol 17a-dehydrogenase activity|17alpha-hydroxysteroid oxidoreductase activity|17alpha-hydroxy steroid oxidoreductase activity|estradiol 17alpha-oxidoreductase activity|17alpha-estradiol dehydrogenase activity|17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase activity											MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN|EC:1.1.1.148		molecular_function											owl:Class	
GO:0050848	biolink:NamedThing	regulation of calcium-mediated signaling	Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.	got7fsn_ti	regulation of calcium-mediated signalling													biological_process											owl:Class	
GO:0021643	biolink:NamedThing	vagus nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	got7fsn_ti	CN X maturation													biological_process											owl:Class	
GO:0034807	biolink:NamedThing	4,5-dihydroxybenzo(a)pyrene methyltransferase activity	Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene.	got7fsn_ti												UM-BBD_reactionID:r1131		molecular_function											owl:Class	
GO:0017095	biolink:NamedThing	heparan sulfate 6-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate.	got7fsn_ti	heparin 6-O-sulfotransferase activity|heparan sulphate 6-O-sulphotransferase activity											Reactome:R-HSA-2076419|EC:2.8.2.-		molecular_function											owl:Class	
GO:0120258	biolink:NamedThing	peptidyl-threonine O-acetylation	The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19957					krc	2020-09-08T18:07:44Z				RESID:AA0364		biological_process											owl:Class	
GO:0005219	biolink:NamedThing	ryanodine-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	ryanodine receptor|caffeine-sensitive calcium-release channel											Reactome:R-HSA-2855020		molecular_function											owl:Class	
GO:0047631	biolink:NamedThing	ADP-ribose diphosphatase activity	Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.	got7fsn_ti	ADPribose diphosphatase activity|ADP-ribose ribophosphohydrolase activity|ADPribose pyrophosphatase activity|adenosine diphosphoribose pyrophosphatase activity|ADP-ribose phosphohydrolase activity|ADP-ribose pyrophosphatase activity|ADPR-PPase activity											MetaCyc:RXN0-1441|Reactome:R-HSA-2393954|Reactome:R-HSA-2393939|RHEA:10412|EC:3.6.1.13|Reactome:R-HSA-5696049		molecular_function											owl:Class	
GO:0102297	biolink:NamedThing	selenate adenylyltransferase activity	Catalysis of the reaction: selenic acid + ATP + 2 H+ <=> adenylyl selenate + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-12720		molecular_function											owl:Class	
GO:0003696	biolink:NamedThing	satellite DNA binding	Binding to satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0060174	biolink:NamedThing	limb bud formation	The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.	got7fsn_ti	limbbud formation|limb formation													biological_process											owl:Class	
GO:0047812	biolink:NamedThing	D-amino-acid N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid.	got7fsn_ti	D-amino acid acetyltransferase activity|acetyl-CoA:D-amino-acid N-acetyltransferase activity|D-amino acid-alpha-N-acetyltransferase activity											EC:2.3.1.36|MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN|RHEA:20704		molecular_function											owl:Class	
GO:0075261	biolink:NamedThing	positive regulation of spore-bearing organ development	Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.	got7fsn_ti														biological_process											owl:Class	
GO:0044658	biolink:NamedThing	pore formation in membrane of host by symbiont	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of a host organism.	got7fsn_ti							jl	2012-08-01T13:14:42Z						biological_process											owl:Class	
GO:0106271	biolink:NamedThing	D-arabinose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-arabinose + NADP+ = D-arabinono-1,4-lactone + NADPH.	got7fsn_ti							hjd	2020-06-23T18:47:25Z				RHEA:21892|EC:1.1.1.117		molecular_function											owl:Class	
GO:0031867	biolink:NamedThing	EP4 subtype prostaglandin E2 receptor binding	Binding to an EP4 subtype prostaglandin E2 receptor.	got7fsn_ti	prostanoid EP4 receptor binding|EP4 subtype prostaglandin E2 receptor ligand													molecular_function											owl:Class	
GO:0042293	biolink:NamedThing	Hub1 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti														molecular_function											owl:Class	
GO:0002140	biolink:NamedThing	stereocilia tip link	A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia.	got7fsn_ti							hjd	2009-05-06T10:28:10Z						cellular_component											owl:Class	
GO:0050042	biolink:NamedThing	lactate-malate transhydrogenase activity	Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate.	got7fsn_ti	(S)-lactate:oxaloacetate oxidoreductase activity|malate-lactate transhydrogenase activity											KEGG_REACTION:R01447|RHEA:10984|EC:1.1.99.7|MetaCyc:LACTATE-MALATE-TRANSHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0090081	biolink:NamedThing	regulation of heart induction by regulation of canonical Wnt signaling pathway	Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes.	got7fsn_ti	regulation of heart induction by regulation of canonical Wnt-activated signaling pathway|regulation of heart induction by regulation of canonical Wnt receptor signaling pathway|regulation of heart induction by regulation of canonical Wnt receptor signalling pathway						tb	2009-10-23T10:55:18Z						biological_process											owl:Class	
GO:0003307	biolink:NamedThing	regulation of Wnt signaling pathway involved in heart development	Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.	got7fsn_ti	regulation of Wnt receptor signalling pathway involved in heart development|regulation of Wnt-activated signaling pathway involved in heart development|regulation of Wnt receptor signaling pathway involved in heart development						dph	2009-10-22T12:32:10Z						biological_process											owl:Class	
GO:0102092	biolink:NamedThing	5-diphosphoinositol pentakisphosphate 3-kinase activity	Catalysis of the reaction: 5-diphospho-1D-myo-inositol pentakisphosphate + ATP = 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP.	got7fsn_ti												EC:2.7.4.24|MetaCyc:RXN-10979		molecular_function											owl:Class	
GO:0071882	biolink:NamedThing	phospholipase C-activating adrenergic receptor signaling pathway	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	activation of phospholipase C activity by adrenergic receptor signaling pathway|activation of phospholipase C activity by adrenergic receptor signalling pathway|adrenergic receptor, phospholipase C activating pathway						mah	2010-09-13T04:32:03Z						biological_process											owl:Class	
GO:0002556	biolink:NamedThing	serotonin secretion by basophil	The regulated release of serotonin by a basophil or group of basophils.	got7fsn_ti	serotonin release by basophil													biological_process											owl:Class	
GO:0030399	biolink:NamedThing	autophagosome membrane disassembly	The controlled breakdown of the membranes of autophagosomes.	got7fsn_ti	autophagic vacuole membrane disassembly|autophagic membrane breakdown|autophagic membrane degradation|autophagic membrane catabolism													biological_process											owl:Class	
GO:0061718	biolink:NamedThing	glucose catabolic process to pyruvate	The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate.	got7fsn_ti	glucose catabolism to pyruvate						dph	2015-06-30T13:17:26Z						biological_process											owl:Class	
GO:0006007	biolink:NamedThing	glucose catabolic process	The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.	got7fsn_ti	glucose breakdown|glucose catabolism|glucose degradation													biological_process											owl:Class	
GO:1990969	biolink:NamedThing	modulation by host of viral RNA-binding transcription factor activity	A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor.	got7fsn_ti	modulation by host of viral Tat activity						bf	2016-06-21T12:12:31Z						biological_process											owl:Class	
GO:0043921	biolink:NamedThing	modulation by host of viral transcription	Any process in which a host organism modulates the frequency, rate or extent of viral transcription.	got7fsn_ti	regulation by host of viral transcription|regulation of viral transcription by host													biological_process											owl:Class	
GO:0035875	biolink:NamedThing	maintenance of meiotic sister chromatid cohesion, centromeric	The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.	got7fsn_ti	maintenance of centromeric meiotic sister chromatin cohesion|maintenance of sister chromatin cohesion at centromere at meiosis I|maintenance of meiotic sister chromatin cohesion at centromere						bf	2011-05-31T09:35:51Z						biological_process											owl:Class	
GO:0010432	biolink:NamedThing	bract development	The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.	got7fsn_ti														biological_process											owl:Class	
GO:0071247	biolink:NamedThing	cellular response to chromate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.	got7fsn_ti							mah	2009-12-03T02:46:01Z						biological_process											owl:Class	
GO:0102468	biolink:NamedThing	wogonin 7-O-glucuronosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin <=> UDP + wogonin 7-O-beta-D-glucuronate + H+.	got7fsn_ti												RHEA:28322|MetaCyc:RXN-14060|EC:2.4.1.253		molecular_function											owl:Class	
GO:0010401	biolink:NamedThing	pectic galactan metabolic process	The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I.	got7fsn_ti	pectic galactan metabolism													biological_process											owl:Class	
GO:0010400	biolink:NamedThing	rhamnogalacturonan I side chain metabolic process	The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I.	got7fsn_ti	rhamnogalacturonan I side chain metabolism													biological_process											owl:Class	
GO:0015274	biolink:NamedThing	organellar voltage-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane.	got7fsn_ti	organellar voltage gated chloride channel activity|organellar voltage-dependent chloride channel activity													molecular_function											owl:Class	
GO:0005247	biolink:NamedThing	voltage-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage gated chloride channel activity|voltage-dependent chloride channel activity											Reactome:R-HSA-2744228		molecular_function											owl:Class	
GO:0032505	biolink:NamedThing	reproduction of a single-celled organism	The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.	got7fsn_ti														biological_process											owl:Class	
GO:0010654	biolink:NamedThing	apical cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote.	got7fsn_ti														biological_process											owl:Class	
GO:0062193	biolink:NamedThing	D-ribose pyranase activity	Catalysis of the reaction: beta-D-ribopyranose = beta-D-ribofuranose.	got7fsn_ti							dph	2019-12-09T16:49:07Z				EC:5.4.99.62|RHEA:25432		molecular_function											owl:Class	
GO:0042275	biolink:NamedThing	error-free postreplication DNA repair	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate.	got7fsn_ti	error-free replication restart|error-free PRR				Note that 'error-free' does not mean that literally zero errors occur during DNA synthesis, but that the error rate is low, comparable to that of DNA synthesis during replication.									biological_process											owl:Class	
GO:0071586	biolink:NamedThing	CAAX-box protein processing	The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.	got7fsn_ti							mah	2010-01-28T04:42:45Z						biological_process											owl:Class	
GO:0072359	biolink:NamedThing	circulatory system development	The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.	got7fsn_ti	cardiovascular system development						mah	2010-11-16T11:27:39Z			GO:0072358			biological_process											owl:Class	
GO:0042164	biolink:NamedThing	interleukin-12 alpha subunit binding	Binding to the alpha subunit of interleukin-12.	got7fsn_ti	IL-12p35 binding|IL-12A binding|CLMFp35 binding|NKSFp35 binding													molecular_function											owl:Class	
GO:0019972	biolink:NamedThing	interleukin-12 binding	Binding to interleukin-12.	got7fsn_ti	IL-12 binding													molecular_function											owl:Class	
GO:0043756	biolink:NamedThing	adenosylcobinamide hydrolase activity	Catalysis of the reaction: adenosylcobinamide + H(2)O = (R)-1-aminopropan-2-ol + adenosylcobyrate.	got7fsn_ti	adenosylcobinamide amidohydrolase activity|CbiZ|AdoCbi hydrolase activity|AdoCbi amidohydrolase activity											KEGG_REACTION:R05226|EC:3.5.1.90|MetaCyc:R346-RXN|RHEA:23504		molecular_function											owl:Class	
GO:0021843	biolink:NamedThing	substrate-independent telencephalic tangential interneuron migration	The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.	got7fsn_ti														biological_process											owl:Class	
GO:0050233	biolink:NamedThing	pyranose oxidase activity	Catalysis of the reaction: D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2).	got7fsn_ti	glucose 2-oxidase activity|pyranose:oxygen 2-oxidoreductase activity|pyranose-2-oxidase activity											KEGG_REACTION:R00302|RHEA:10552|EC:1.1.3.10|MetaCyc:PYRANOSE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0051622	biolink:NamedThing	negative regulation of norepinephrine uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.	got7fsn_ti	downregulation of norepinephrine uptake|negative regulation of levarterenol uptake|negative regulation of noradrenaline uptake|down regulation of norepinephrine uptake|negative regulation of norepinephrine import|down-regulation of norepinephrine uptake													biological_process											owl:Class	
GO:0009959	biolink:NamedThing	negative gravitropism	The orientation of plant parts away from gravity.	got7fsn_ti	shoot gravitropism													biological_process											owl:Class	
GO:0102372	biolink:NamedThing	alpha-amyrin 28-monooxygenase activity	Catalysis of the reaction: alpha-amyrin + NADPH(4-) + O2 + H+ <=> uvaol + NADP(3-) + H2O.	got7fsn_ti												MetaCyc:RXN-13500		molecular_function											owl:Class	
GO:0034893	biolink:NamedThing	N-nitrodimethylamine hydroxylase activity	Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O.	got7fsn_ti												UM-BBD_reactionID:r1395		molecular_function											owl:Class	
GO:0030975	biolink:NamedThing	thiamine binding	Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.	got7fsn_ti	vitamin B1 binding|thiamin binding													molecular_function											owl:Class	
GO:0015944	biolink:NamedThing	formate oxidation	The chemical reactions and pathways by which formate is converted to CO2.	got7fsn_ti	formic acid oxidation											MetaCyc:PWY-1881		biological_process											owl:Class	
GO:0015942	biolink:NamedThing	formate metabolic process	The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.	got7fsn_ti	formate metabolism													biological_process											owl:Class	
GO:0050376	biolink:NamedThing	UDP-glucosamine 4-epimerase activity	Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine.	got7fsn_ti	UDP-glucosamine epimerase activity|UDPglucosamine 4-epimerase activity											RHEA:23492|MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN|EC:5.1.3.16		molecular_function											owl:Class	
GO:0061872	biolink:NamedThing	hepatic stellate cell contraction	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell.	got7fsn_ti							dph	2017-05-01T13:25:18Z						biological_process											owl:Class	
GO:0102633	biolink:NamedThing	flaviolin monooxygenase activity	Catalysis of the reaction: flaviolin-2-olate + NADH + H+ + O2 <=> mompain + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-15585		molecular_function											owl:Class	
GO:0035819	biolink:NamedThing	positive regulation of renal sodium excretion by pressure natriuresis	An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.	got7fsn_ti	natriuresis resulting from pressure natriuresis						bf	2011-04-20T01:57:20Z						biological_process											owl:Class	
GO:0009722	biolink:NamedThing	detection of cytokinin stimulus	The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of cytokinin stimulus													biological_process											owl:Class	
GO:0009735	biolink:NamedThing	response to cytokinin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.	got7fsn_ti	response to cytokinin stimulus													biological_process											owl:Class	
GO:0035687	biolink:NamedThing	T-helper 1 cell extravasation	The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.	got7fsn_ti	Th1 cell extravasation						bf	2011-02-24T10:10:00Z						biological_process											owl:Class	
GO:0033769	biolink:NamedThing	glyceollin synthase activity	Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O.	got7fsn_ti	2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,NADPH:oxygen oxidoreductase (cyclizing) activity|dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity											MetaCyc:2.5.1.36-RXN|EC:1.14.13.85		molecular_function											owl:Class	
GO:0106384	biolink:NamedThing	dGMP salvage	Any process which produces a dGMP from derivatives of it, without de novo synthesis.	got7fsn_ti							hjd	2021-06-11T19:36:06Z						biological_process											owl:Class	
GO:0072353	biolink:NamedThing	cellular age-dependent response to reactive oxygen species	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.	got7fsn_ti							mah	2010-11-12T11:27:27Z						biological_process											owl:Class	
GO:0001315	biolink:NamedThing	age-dependent response to reactive oxygen species	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.	got7fsn_ti	age-dependent response to active oxygen species|age-dependent response to ROI|age-dependent response to reactive oxidative species|age-dependent response to ROS|age-dependent response to AOS|age-dependent response to reactive oxygen intermediate													biological_process											owl:Class	
GO:0010027	biolink:NamedThing	thylakoid membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.	got7fsn_ti	thylakoid membrane organization and biogenesis|thylakoid membrane organisation				See also the cellular component term 'thylakoid membrane ; GO:0042651'.									biological_process											owl:Class	
GO:0006665	biolink:NamedThing	sphingolipid metabolic process	The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	got7fsn_ti	sphingolipid metabolism													biological_process											owl:Class	
GO:0006643	biolink:NamedThing	membrane lipid metabolic process	The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.	got7fsn_ti	membrane lipid metabolism													biological_process											owl:Class	
GO:0071968	biolink:NamedThing	lipid A-core heptosyltransferase activity	Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+.	got7fsn_ti							mah	2010-10-14T05:15:22Z				MetaCyc:RXN0-5127|RHEA:30019		molecular_function											owl:Class	
GO:0047939	biolink:NamedThing	L-glucuronate reductase activity	Catalysis of the reaction: L-gulonate + NADP(+) = D-glucuronate + H(+) + NADPH.	got7fsn_ti	TPN-L-gulonate dehydrogenase activity|D-glucuronate reductase activity|aldehyde reductase II activity|D-glucuronate dehydrogenase activity|glucuronate dehydrogenase activity|NADP-L-gulonate dehydrogenase activity|glucuronate reductase activity											Reactome:R-HSA-5661256|KEGG_REACTION:R01481|RHEA:14909|EC:1.1.1.19|MetaCyc:GLUCURONATE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0055069	biolink:NamedThing	zinc ion homeostasis	Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.	got7fsn_ti	zinc homeostasis													biological_process											owl:Class	
GO:0102556	biolink:NamedThing	dammarenediol 12-hydroxylase activity	Catalysis of the reaction: dammarenediol-II + NADPH + H+ + O2 <=> (20S)-protopanaxadiol + NADP + H2O.	got7fsn_ti												EC:1.14.14.120|MetaCyc:RXN-14975|RHEA:38579		molecular_function											owl:Class	
GO:0086027	biolink:NamedThing	AV node cell to bundle of His cell signaling	Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte.	got7fsn_ti	atrioventricular node to bundle of His cell signaling|AV node cell to bundle of His cell signalling						tb	2011-11-11T02:02:14Z						biological_process											owl:Class	
GO:0086019	biolink:NamedThing	cell-cell signaling involved in cardiac conduction	Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium.	got7fsn_ti	cell-cell signalling involved in cardiac conduction						dph	2011-11-16T03:43:52Z						biological_process											owl:Class	
GO:0036195	biolink:NamedThing	muscle cell projection membrane	The portion of the plasma membrane surrounding a muscle cell projection.	got7fsn_ti							bf	2012-04-20T10:21:51Z						cellular_component											owl:Class	
GO:0047897	biolink:NamedThing	formate-dihydrofolate ligase activity	Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H(+) + phosphate.	got7fsn_ti	formyl dihydrofolate synthase activity|formate:dihydrofolate ligase (ADP-forming)|dihydrofolate formyltransferase activity											MetaCyc:FORMATE--DIHYDROFOLATE-LIGASE-RXN|RHEA:24328|EC:6.3.4.17|KEGG_REACTION:R02238		molecular_function											owl:Class	
GO:0003051	biolink:NamedThing	angiotensin-mediated drinking behavior	The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst.	got7fsn_ti	angiotensin mediated drinking behavior													biological_process											owl:Class	
GO:0042756	biolink:NamedThing	drinking behavior	The specific behavior of an organism relating to the intake of liquids, especially water.	got7fsn_ti	drinking behaviour													biological_process											owl:Class	
GO:0038045	biolink:NamedThing	large latent transforming growth factor-beta complex	A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors.	got7fsn_ti	LLC|large latent complex						bf	2011-11-03T04:29:49Z						cellular_component											owl:Class	
GO:0099129	biolink:NamedThing	cochlear outer hair cell electromotile response	A rapid, force generating length change of an outer hair cell in response to electical stimulation.  This occurs naturally as during hearing where it serves a source of mechanical amplification.	got7fsn_ti														biological_process											owl:Class	
GO:0018356	biolink:NamedThing	protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine	The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine.	got7fsn_ti											GO:0018382	RESID:AA0258		biological_process											owl:Class	
GO:0044731	biolink:NamedThing	Ost-alpha/Ost-beta complex	A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity.	got7fsn_ti	Ost alpha-Ost beta complex|(Ost)2 complex|SLC51 complex						jl	2012-11-06T13:42:06Z						cellular_component											owl:Class	
GO:0099142	biolink:NamedThing	intracellularly ATP-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.	got7fsn_ti														molecular_function											owl:Class	
GO:0050301	biolink:NamedThing	streptomycin-6-phosphatase activity	Catalysis of the reaction: H(2)O + streptomycin 6-phosphate = phosphate + streptomycin.	got7fsn_ti	streptomycin-6-P phosphohydrolase activity|streptomycin 6-phosphate phosphohydrolase activity|streptomycin-6-phosphate phosphohydrolase activity|streptomycin 6-phosphate phosphatase activity											RHEA:10688|KEGG_REACTION:R02228|EC:3.1.3.39|MetaCyc:STREPTOMYCIN-6-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0035726	biolink:NamedThing	common myeloid progenitor cell proliferation	The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage.	got7fsn_ti							bf	2011-03-10T02:57:19Z						biological_process											owl:Class	
GO:0036433	biolink:NamedThing	di-trans, poly-cis-undecaprenol kinase activity	Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.	got7fsn_ti	ditrans,polycis-undecaprenol kinase activity						bf	2013-09-16T14:21:12Z				MetaCyc:UNDECAPRENOL-KINASE-RXN|RHEA:28122|KEGG_REACTION:R05626		molecular_function											owl:Class	
GO:0002511	biolink:NamedThing	central B cell receptor editing	Receptor editing occurring in B cells in the bone marrow.	got7fsn_ti	central B lymphocyte receptor editing|central B-cell receptor editing|central B-lymphocyte receptor editing													biological_process											owl:Class	
GO:0060296	biolink:NamedThing	regulation of cilium beat frequency involved in ciliary motility	Any process that modulates the frequency of cilium beating involved in ciliary motility.	got7fsn_ti														biological_process											owl:Class	
GO:0047231	biolink:NamedThing	pyridoxine 5'-O-beta-D-glucosyltransferase activity	Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP.	got7fsn_ti	UDP-glucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity|UDP-glucose:pyridoxine 5'-O-beta-glucosyltransferase activity|UDP-glucose-pyridoxine glucosyltransferase activity|UDPglucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-pyridoxine 5'-beta-glucosyltransferase activity											MetaCyc:2.4.1.160-RXN|EC:2.4.1.160|KEGG_REACTION:R01912|RHEA:20177		molecular_function											owl:Class	
GO:0018819	biolink:NamedThing	lactoyl-CoA dehydratase activity	Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.	got7fsn_ti	lactoyl-CoA hydro-lyase activity|lactyl-coenzyme A dehydrase activity|lactoyl coenzyme A dehydratase activity|lactyl CoA dehydratase activity|lactoyl-CoA hydro-lyase (acryloyl-CoA-forming)|acrylyl coenzyme A hydratase activity											EC:4.2.1.54|UM-BBD_reactionID:r0086|RHEA:21056|MetaCyc:LACTOYL-COA-DEHYDRATASE-RXN|MetaCyc:RXN-781		molecular_function											owl:Class	
GO:0060164	biolink:NamedThing	regulation of timing of neuron differentiation	The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron.	got7fsn_ti														biological_process											owl:Class	
GO:0042867	biolink:NamedThing	pyruvate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.	got7fsn_ti	pyruvate breakdown|pyruvate degradation|pyruvate catabolism													biological_process											owl:Class	
GO:0071728	biolink:NamedThing	beak development	The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.	got7fsn_ti							mah	2010-03-17T03:52:48Z						biological_process											owl:Class	
GO:0036488	biolink:NamedThing	CHOP-C/EBP complex	A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors.	got7fsn_ti	CHOP-C/EBP dimer|GADD153-C/EBP-alpha complex|CHOP-C/EBP heterodimer|GADD153-C/EBP complex						bf	2014-11-06T13:18:49Z						cellular_component											owl:Class	
GO:0009689	biolink:NamedThing	induction of phytoalexin biosynthetic process	The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection.	got7fsn_ti	induction of phytoalexin anabolism|induction of phytoalexin synthesis|induction of phytoalexin formation|induction of phytoalexin biosynthesis													biological_process											owl:Class	
GO:0060757	biolink:NamedThing	adult foraging behavior	Behavior by which an adult locates food.	got7fsn_ti							dph	2009-06-22T02:50:56Z						biological_process											owl:Class	
GO:0106264	biolink:NamedThing	protein serine kinase activity (using GTP as donor)	Catalysis of the reactions: GTP + L-seryl-[protein] = GDP + H(+) + O-phospho-L-seryl-[protein].	got7fsn_ti							hjd	2020-05-28T18:51:18Z				RHEA:64020		molecular_function											owl:Class	
GO:0032627	biolink:NamedThing	interleukin-23 production	The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-23 biosynthetic process|interleukin-23 secretion|IL-23 production										GO:0042240|GO:0072621			biological_process											owl:Class	
GO:0045140	biolink:NamedThing	inositol phosphoceramide synthase activity	Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide + diacylglycerol.	got7fsn_ti	IPC synthase activity											EC:2.7.1.227|MetaCyc:RXN3O-581		molecular_function											owl:Class	
GO:0004300	biolink:NamedThing	enoyl-CoA hydratase activity	Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O.	got7fsn_ti	enoyl coenzyme A hydrase (D)|crotonyl hydrase activity|unsaturated acyl-CoA hydratase activity|(3S)-3-hydroxyacyl-CoA hydro-lyase activity|short chain enoyl coenzyme A hydratase activity|2-enoyl-CoA hydratase activity|enoyl coenzyme A hydrase (L)|enol-CoA hydratase activity|hydratase, enoyl coenzyme A|short-chain enoyl-CoA hydratase activity|ECH|trans-2-enoyl-CoA hydratase activity|beta-hydroxyacid dehydrase activity|beta-hydroxyacyl-CoA dehydrase activity|D-3-hydroxyacyl-CoA dehydratase|enoyl coenzyme A hydratase activity|enoyl hydrase activity|2-octenoyl coenzyme A hydrase activity|acyl coenzyme A hydrase activity										GO:0016510	EC:4.2.1.17|Reactome:R-HSA-77344|Reactome:R-HSA-77325|UM-BBD_enzymeID:e0014|Reactome:R-HSA-70830|Reactome:R-HSA-77301|Reactome:R-HSA-77277|Reactome:R-HSA-77333|Reactome:R-HSA-77314|Reactome:R-HSA-70870|RHEA:16105|MetaCyc:ENOYL-COA-HYDRAT-RXN|Reactome:R-HSA-77256		molecular_function											owl:Class	
GO:0098567	biolink:NamedThing	periplasmic side of plasma membrane	The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface.	got7fsn_ti							dos	2013-12-19T09:31:30Z						cellular_component											owl:Class	
GO:0044762	biolink:NamedThing	negative regulation by symbiont of host neurotransmitter secretion	Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism.	got7fsn_ti							jl	2012-12-06T15:52:20Z						biological_process											owl:Class	
GO:0044079	biolink:NamedThing	modulation by symbiont of host neurotransmitter secretion	Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism.	got7fsn_ti	modification by symbiont of host neurotransmitter secretion|regulation by symbiont of host neurotransmitter secretion|modulation of host neurotransmitter secretion by symbiont													biological_process											owl:Class	
GO:0050057	biolink:NamedThing	linamarin synthase activity	Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin.	got7fsn_ti	UDPglucose:ketone cyanohydrin beta-glucosyltransferase activity|uridine diphosphate-glucose-ketone cyanohydrin beta-glucosyltransferase activity|uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase activity|UDPglucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity|UDP-glucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity|uridine diphosphoglucose-ketone glucosyltransferase activity|UDP glucose ketone cyanohydrin glucosyltransferase activity											EC:2.4.1.63|MetaCyc:LINAMARIN-SYNTHASE-RXN|RHEA:20009		molecular_function											owl:Class	
GO:0047976	biolink:NamedThing	hamamelose kinase activity	Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H(+).	got7fsn_ti	hamamelosekinase (ATP: hamamelose 2'-phosphotransferase)|hamamelose kinase (phosphorylating)|ATP/hamamelose 2'-phosphotransferase activity|ATP:D-hamamelose 2'-phosphotransferase activity											MetaCyc:HAMAMELOSE-KINASE-RXN|KEGG_REACTION:R03766|RHEA:22796|EC:2.7.1.102		molecular_function											owl:Class	
GO:0004946	biolink:NamedThing	bombesin receptor activity	Combining with bombesin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0031858	biolink:NamedThing	pituitary adenylate cyclase-activating polypeptide receptor binding	Binding to a pituitary adenylate cyclase-activating polypeptide receptor.	got7fsn_ti	pituitary adenylate cyclase-activating peptide receptor ligand|pituitary adenylate cyclase activating peptide receptor binding|PACAP receptor binding													molecular_function											owl:Class	
GO:0034542	biolink:NamedThing	trimethylarsine oxidase activity	Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O.	got7fsn_ti												EC:1.97.1.-|UM-BBD_reactionID:r0807		molecular_function											owl:Class	
GO:0005231	biolink:NamedThing	excitatory extracellular ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential.	got7fsn_ti												Reactome:R-HSA-432164|Reactome:R-HSA-438037|Reactome:R-HSA-399712|Reactome:R-HSA-399711|Reactome:R-HSA-420980		molecular_function											owl:Class	
GO:0003424	biolink:NamedThing	establishment of cell polarity involved in growth plate cartilage chondrocyte division	The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte.	got7fsn_ti	growth plate cartilage chondrocyte polarization						dph	2009-12-22T10:18:10Z						biological_process											owl:Class	
GO:0140538	biolink:NamedThing	negative regulation of conjugation with zygote	A process that prevents a zygote from fusing an additional cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16329					pg	2020-11-07T07:50:23Z						biological_process											owl:Class	
GO:0031138	biolink:NamedThing	negative regulation of conjugation with cellular fusion	Any process that decreases the rate or frequency of conjugation with cellular fusion.	got7fsn_ti	down regulation of conjugation with cellular fusion|inhibition of conjugation with cellular fusion|downregulation of conjugation with cellular fusion|down-regulation of conjugation with cellular fusion													biological_process											owl:Class	
GO:0075003	biolink:NamedThing	adhesion of symbiont appressorium to host	The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	adhesion of symbiont appressorium to host during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21505			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0047635	biolink:NamedThing	alanine-oxo-acid transaminase activity	Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.	got7fsn_ti	L-alanine:2-oxo-acid aminotransferase activity|alanine--oxo-acid aminotransferase activity|alanine-keto acid aminotransferase activity|leucine-alanine transaminase activity|alanine-oxo acid aminotransferase activity|L-alanine-alpha-keto acid aminotransferase activity|alanine-oxo-acid aminotransferase activity											EC:2.6.1.12|RHEA:19953|MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0080140	biolink:NamedThing	regulation of jasmonic acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid.	got7fsn_ti							dhl	2009-05-19T04:24:55Z						biological_process											owl:Class	
GO:0019217	biolink:NamedThing	regulation of fatty acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.	got7fsn_ti	regulation of fatty acid metabolism										GO:0006632			biological_process											owl:Class	
GO:0043014	biolink:NamedThing	alpha-tubulin binding	Binding to the microtubule constituent protein alpha-tubulin.	got7fsn_ti	alpha tubulin binding													molecular_function											owl:Class	
GO:0070486	biolink:NamedThing	leukocyte aggregation	The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.	got7fsn_ti	immune cell aggregation|leucocyte aggregation|white blood cell aggregation|white corpuscle aggregation													biological_process											owl:Class	
GO:0090523	biolink:NamedThing	cytochrome-b5 reductase activity, acting on NADPH	Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome b(5) = NADP+ + 2 ferrocytochrome b(5).	got7fsn_ti	cytochrome-b5 reductase activity						tb	2013-01-11T12:21:41Z				RHEA:64576		molecular_function											owl:Class	
GO:0016041	biolink:NamedThing	glutamate synthase (ferredoxin) activity	Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.	got7fsn_ti	L-glutamate:ferredoxin oxidoreductase (transaminating)|glutamate synthase (ferredoxin-dependent)|ferredoxin-glutamate synthase activity|ferredoxin-dependent glutamate synthase activity											MetaCyc:GLUTAMATE-SYNTHASE-FERREDOXIN-RXN|EC:1.4.7.1|MetaCyc:PWY-4341|RHEA:12128		molecular_function											owl:Class	
GO:0036193	biolink:NamedThing	2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity	Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.	got7fsn_ti							bf	2012-04-19T11:54:34Z				EC:1.14.14.110|RHEA:31939|KEGG_REACTION:R07423		molecular_function											owl:Class	
GO:0004130	biolink:NamedThing	cytochrome-c peroxidase activity	Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O.	got7fsn_ti	apocytochrome c peroxidase activity|cytochrome c-H2O oxidoreductase activity|cytochrome c peroxidase activity|mesocytochrome c peroxidase azide|cytochrome peroxidase activity|cytochrome c-551 peroxidase activity|mesocytochrome c peroxidase cyanide|mesocytochrome c peroxidase cyanate|ferrocytochrome-c:hydrogen-peroxide oxidoreductase activity											EC:1.11.1.5|MetaCyc:CYTOCHROME-C-PEROXIDASE-RXN|RHEA:16581		molecular_function											owl:Class	
GO:0030294	biolink:NamedThing	receptor signaling protein tyrosine kinase inhibitor activity	Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase.	got7fsn_ti	receptor signalling protein tyrosine kinase inhibitor activity													molecular_function											owl:Class	
GO:0030292	biolink:NamedThing	protein tyrosine kinase inhibitor activity	Stops, prevents or reduces the activity of a protein tyrosine kinase.	got7fsn_ti														molecular_function											owl:Class	
GO:0032249	biolink:NamedThing	regulation of adenosine transport	Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0036110	biolink:NamedThing	cellular response to inositol starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.	got7fsn_ti							bf	2012-02-15T10:46:07Z						biological_process											owl:Class	
GO:0030108	biolink:NamedThing	HLA-A specific activating MHC class I receptor activity	Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.	got7fsn_ti														molecular_function											owl:Class	
GO:0032397	biolink:NamedThing	activating MHC class I receptor activity	Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.	got7fsn_ti														molecular_function											owl:Class	
GO:0032841	biolink:NamedThing	calcitonin binding	Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.	got7fsn_ti														molecular_function											owl:Class	
GO:0097737	biolink:NamedThing	acquisition of mycelium reproductive competence	A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium.	got7fsn_ti	mycelium developmental competence						pr	2016-10-14T16:36:09Z						biological_process											owl:Class	
GO:0047427	biolink:NamedThing	cyanoalanine nitrilase activity	Catalysis of the reaction: 3-cyano-L-alanine + 2 H(2)O + H(+) = L-aspartate + NH(4)(+).	got7fsn_ti	3-cyano-L-alanine aminohydrolase activity|beta-cyanoalanine nitrilase activity											EC:3.5.5.4|MetaCyc:3.5.5.4-RXN|RHEA:11188|KEGG_REACTION:R00486		molecular_function											owl:Class	
GO:0014845	biolink:NamedThing	stomach body smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.	got7fsn_ti														biological_process											owl:Class	
GO:0014828	biolink:NamedThing	distal stomach smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus.	got7fsn_ti														biological_process											owl:Class	
GO:1904606	biolink:NamedThing	fat cell apoptotic process	Any apoptotic process in a fat cell.	got7fsn_ti	adipose cell apoptotic process|adipocyte apoptotic process|adipose cell apoptosis|fat cell apoptosis|adipocyte apoptosis						sl	2015-08-27T18:13:06Z						biological_process											owl:Class	
GO:0050211	biolink:NamedThing	procollagen galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine.	got7fsn_ti	uridine diphosphogalactose-collagen galactosyltransferase activity|collagen hydroxylysyl galactosyltransferase activity|collagen galactosyltransferase activity|UDPgalactose:5-hydroxylysine-collagen galactosyltransferase activity|UDP galactose-collagen galactosyltransferase activity|hydroxylysine galactosyltransferase activity|UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity|UDPgalactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity											MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN|RHEA:12637|Reactome:R-HSA-1981128|Reactome:R-HSA-1981120|EC:2.4.1.50		molecular_function											owl:Class	
GO:0046488	biolink:NamedThing	phosphatidylinositol metabolic process	The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.	got7fsn_ti	PtdIns metabolic process|phosphoinositide metabolic process|phosphatidylinositol metabolism|PtdIns metabolism|phosphoinositide metabolism										GO:0030384			biological_process											owl:Class	
GO:0050575	biolink:NamedThing	2-(S)-hydroxypropyl-CoM dehydrogenase activity	Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH.	got7fsn_ti	2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity|2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase activity											KEGG_REACTION:R05690|RHEA:21052|EC:1.1.1.269|UM-BBD_reactionID:r0853|MetaCyc:1.1.1.269-RXN		molecular_function											owl:Class	
GO:0003090	biolink:NamedThing	positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.	got7fsn_ti	positive regulation of heart contraction by epinephrine-norepinephrine|positive regulation of heart contraction by adrenaline-noradrenaline|increased force of heart contraction by neuronal adrenaline-noradrenaline|increased force of heart contraction by epinephrine-norepinephrine released from the nerve endings|increased force of heart contraction by neuronal epinephrine-norepinephrine													biological_process											owl:Class	
GO:0034965	biolink:NamedThing	intronic box C/D RNA processing	Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.	got7fsn_ti	intronic box C/D snoRNA processing|intronic box C/D sRNA processing													biological_process											owl:Class	
GO:0031070	biolink:NamedThing	intronic snoRNA processing	The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0002538	biolink:NamedThing	arachidonic acid metabolite production involved in inflammatory response	The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels.	got7fsn_ti	production of arachidonic acid metabolites involved in acute inflammatory response|arachidonic acid metabolite production involved in acute inflammatory response|production of arachidonic acid metabolites involved in inflammatory response													biological_process											owl:Class	
GO:0099091	biolink:NamedThing	postsynaptic specialization, intracellular component	A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.	got7fsn_ti														cellular_component											owl:Class	
GO:0140649	biolink:NamedThing	cell-to-cell migration by invasive hypha	The directional movement of a hyphal filament from one host cell to another. This process involves the clearance of plant-derived plasmodesmal occlusion materials, cytoskeleton based constriction of invasive hypha to traverse plasmodesmata. Septins and F-actin are reorganized into an hourglass shape at the point of maximum hyphal constriction.	got7fsn_ti	plant tissue colonization|host tissue colonization|invasive growth|invasive hyphae formation	https://github.com/geneontology/go-ontology/issues/21125			Do not confuse with ' GO:0036267 invasive filamentous growth ', which doesn't include invasion of cells within the host.		pg	2021-05-25T07:42:38Z						biological_process											owl:Class	
GO:0052717	biolink:NamedThing	tRNA-specific adenosine-34 deaminase activity	Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule.	got7fsn_ti	tRNA(Ala)-A34 deaminase activity						ai	2011-08-12T11:48:54Z						molecular_function											owl:Class	
GO:0008064	biolink:NamedThing	regulation of actin polymerization or depolymerization	Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.	got7fsn_ti														biological_process											owl:Class	
GO:0001156	biolink:NamedThing	TFIIIC-class transcription factor complex binding	Binding to a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.	got7fsn_ti	TFIIIC-class transcription factor binding						krc	2011-01-27T05:02:22Z						molecular_function											owl:Class	
GO:0009051	biolink:NamedThing	pentose-phosphate shunt, oxidative branch	The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).	got7fsn_ti	oxidative branch, pentose pathway|pentose phosphate pathway, oxidative branch|pentose-phosphate pathway, oxidative branch|pentose phosphate shunt, oxidative branch|oxidative pentose phosphate pathway											MetaCyc:OXIDATIVEPENT-PWY		biological_process											owl:Class	
GO:0120105	biolink:NamedThing	mitotic actomyosin contractile ring, intermediate layer	The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer.	got7fsn_ti	actomyosin contractile ring, intermediate layer						krc	2017-10-11T22:54:40Z						cellular_component											owl:Class	
GO:0006009	biolink:NamedThing	glucose 1-phosphate phosphorylation	The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0034323	biolink:NamedThing	O-butanoyltransferase activity	Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0003196	biolink:NamedThing	ventriculo bulbo valve formation	The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti							dph	2009-10-08T01:16:02Z						biological_process											owl:Class	
GO:0005459	biolink:NamedThing	UDP-galactose transmembrane transporter activity	Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.	got7fsn_ti												Reactome:R-HSA-735702|Reactome:R-HSA-5652099		molecular_function											owl:Class	
GO:0042014	biolink:NamedThing	interleukin-19 receptor activity	Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-19R|IL-19 receptor activity													molecular_function											owl:Class	
GO:0030598	biolink:NamedThing	rRNA N-glycosylase activity	Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species.	got7fsn_ti	rRNA N-glycohydrolase activity|mirabilis antiviral protein|saporins|rRNA N-glycosidase activity|ricin|ribosomal ribonucleate N-glycosidase activity|gelonin|momorcochin-S|nigrin b|RNA N-glycosidase activity											MetaCyc:3.2.2.22-RXN|EC:3.2.2.22		molecular_function											owl:Class	
GO:0030597	biolink:NamedThing	RNA glycosylase activity	Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0039540	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	got7fsn_ti	suppression by virus of host RIG-I signaling pathway|suppression by virus of host RIG-I activity|inhibition by virus of host RIG-I|inhibition by virus of host DDX58 activity|inhibition of host DDX58/RIG-I by virus|suppression by virus of host DDX58 signaling pathway|inhibition by virus of host RIG-I signaling|suppression by virus of host RIG-I signalling pathway	https://github.com/geneontology/go-ontology/issues/21984			This term is for annotation of viral proteins that counteract the host anti-viral innate immune response initiated by host RIG-I, either by binding and inhibiting host RIG-I directly, or by interfering with other processes so that RIG-I is unable to carry out its normal function (e.g. by processing viral RNA so it cannot be recognized by RIG-I, or by promoting the degradation of RIG-I).		bf	2012-01-18T02:24:20Z			GO:0039538			biological_process											owl:Class	
GO:0008829	biolink:NamedThing	dCTP deaminase activity	Catalysis of the reaction: dCTP + H2O = dUTP + NH3.	got7fsn_ti	deoxycytidine triphosphate deaminase activity|5-methyl-dCTP deaminase activity|dCTP aminohydrolase activity											MetaCyc:DCTP-DEAM-RXN|EC:3.5.4.13|RHEA:22680|Reactome:R-HSA-180632		molecular_function											owl:Class	
GO:0047150	biolink:NamedThing	betaine-homocysteine S-methyltransferase activity	Catalysis of the reaction: L-homocysteine + betaine = N,N-dimethylglycine + L-methionine.	got7fsn_ti	trimethylammonioacetate:L-homocysteine S-methyltransferase activity|betaine-homocysteine transmethylase activity|betaine-homocysteine methyltransferase activity											Reactome:R-HSA-1614654|EC:2.1.1.5|RHEA:22336|KEGG_REACTION:R02821|MetaCyc:2.1.1.5-RXN		molecular_function											owl:Class	
GO:0102074	biolink:NamedThing	OPC6-trans-2-enoyl-CoA hydratase activity	Catalysis of the reaction: OPC6-3-hydroxyacyl-CoA <=> OPC6-trans-2-enoyl-CoA + H2O.	got7fsn_ti												MetaCyc:RXN-10704		molecular_function											owl:Class	
GO:0050968	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of pain	The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.	got7fsn_ti	perception of pain, sensory detection of chemical stimulus|chemical nociception|sensory detection of chemical stimulus during perception of pain|perception of pain, detection of chemical stimulus|sensory transduction of chemical stimulus during perception of pain|perception of pain, sensory transduction of chemical stimulus													biological_process											owl:Class	
GO:0004161	biolink:NamedThing	dimethylallyltranstransferase activity	Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.	got7fsn_ti	geranyl pyrophosphate synthase activity|trans-farnesyl pyrophosphate synthetase activity|geranyl-diphosphate synthase activity|dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity|geranyl pyrophosphate synthetase activity|DMAPP:IPP-dimethylallyltransferase activity|(2E,6E)-farnesyl diphosphate synthetase activity|geranyl diphosphate synthase|dimethylallyltransferase activity|diprenyltransferase activity				Note that this is the first step in the formation of farnesyl diphosphate. The second step is 'geranyltranstransferase activity ; GO:0004337'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'.							MetaCyc:GPPSYN-RXN|RHEA:22408|EC:2.5.1.1|Reactome:R-HSA-191322		molecular_function											owl:Class	
GO:0002564	biolink:NamedThing	alternate splicing of immunoglobulin genes	The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.	got7fsn_ti	alternate splicing of antibody genes													biological_process											owl:Class	
GO:0061406	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose.	got7fsn_ti							dph	2012-01-12T11:16:10Z						biological_process											owl:Class	
GO:0008478	biolink:NamedThing	pyridoxal kinase activity	Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.	got7fsn_ti	vitamin B(6) kinase activity|pyridoxal phosphokinase activity|pyridoxal 5-phosphate-kinase activity|vitamin B6 kinase activity|pyridoxal kinase (phosphorylating)|ATP:pyridoxal 5'-phosphotransferase activity|pyridoxamine kinase activity|pyridoxine kinase activity											RHEA:10224|MetaCyc:PYRIDOXKIN-RXN|Reactome:R-HSA-964962|Reactome:R-HSA-964970|Reactome:R-HSA-964958|EC:2.7.1.35		molecular_function											owl:Class	
GO:0060944	biolink:NamedThing	neural crest-derived cardiac fibroblast cell fate commitment	The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T02:42:39Z						biological_process											owl:Class	
GO:0060937	biolink:NamedThing	cardiac fibroblast cell fate commitment	The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T01:24:59Z						biological_process											owl:Class	
GO:0008675	biolink:NamedThing	2-dehydro-3-deoxy-phosphogluconate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate.	got7fsn_ti	2-keto-3-deoxy-6-phosphogluconate aldolase activity|KDPG aldolase activity|phospho-2-dehydro-3-deoxygluconate aldolase activity|ODPG aldolase activity|6-phospho-2-keto-3-deoxygluconate aldolase activity|2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)|KDPG-aldolase activity|2-keto-3-deoxygluconate-6-P-aldolase activity|2-keto-3-deoxy-6-phosphogluconic aldolase activity|2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity|2-keto-3-deoxygluconate-6-phosphate aldolase activity|2-oxo-3-deoxy-6-phosphogluconate aldolase activity|phospho-2-keto-3-deoxygluconic aldolase activity|phospho-2-keto-3-deoxygluconate aldolase activity											EC:4.1.2.14|MetaCyc:KDPGALDOL-RXN|RHEA:17089		molecular_function											owl:Class	
GO:0015369	biolink:NamedThing	calcium:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).	got7fsn_ti	calcium:hydrogen antiporter activity											Reactome:R-HSA-8949687|RHEA:29671		molecular_function											owl:Class	
GO:0015368	biolink:NamedThing	calcium:cation antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in).	got7fsn_ti												Reactome:R-HSA-425822		molecular_function											owl:Class	
GO:0070928	biolink:NamedThing	regulation of mRNA stability, ncRNA-mediated	Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.	got7fsn_ti	regulation of mRNA stability, non-coding RNA-mediated|ncRNA-mediated regulation of mRNA stability						mah	2009-09-16T03:26:21Z						biological_process											owl:Class	
GO:0047282	biolink:NamedThing	dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity	Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H(+).	got7fsn_ti	thymidine diphosphodihydrostreptose-streptidine 6-phosphate dihydrostreptosyltransferase activity|dTDPdihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity|dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase activity											RHEA:24392|KEGG_REACTION:R04222|MetaCyc:2.4.2.27-RXN|EC:2.4.2.27		molecular_function											owl:Class	
GO:0005818	biolink:NamedThing	aster	An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores.	got7fsn_ti														cellular_component											owl:Class	
GO:0019061	biolink:NamedThing	uncoating of virus	The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome.	got7fsn_ti	viral uncoating													biological_process											owl:Class	
GO:0009523	biolink:NamedThing	photosystem II	A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center.	got7fsn_ti												Wikipedia:Photosystem_II		cellular_component											owl:Class	
GO:0045169	biolink:NamedThing	fusome	A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle.	got7fsn_ti														cellular_component											owl:Class	
GO:0017075	biolink:NamedThing	syntaxin-1 binding	Binding to a syntaxin-1 SNAP receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0004352	biolink:NamedThing	glutamate dehydrogenase (NAD+) activity	Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+.	got7fsn_ti	NAD-specific glutamic dehydrogenase activity|NAD-dependent glutamate dehydrogenase activity|NAD:glutamate oxidoreductase activity|NAD-dependent glutamic dehydrogenase activity|NAD-glutamate dehydrogenase activity|glutamic acid dehydrogenase|L-glutamate dehydrogenase|glutamate dehydrogenase (NAD)|glutamate oxidoreductase activity|L-glutamate:NAD+ oxidoreductase (deaminating)|NAD-specific glutamate dehydrogenase activity|NADH-linked glutamate dehydrogenase activity|NAD-linked glutamic dehydrogenase activity|glutamic dehydrogenase activity|NAD-linked glutamate dehydrogenase activity											RHEA:15133|MetaCyc:GLUTAMATE-DEHYDROGENASE-RXN|EC:1.4.1.2		molecular_function											owl:Class	
GO:0001110	biolink:NamedThing	promoter clearance from RNA polymerase III promoter	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase.	got7fsn_ti							krc	2010-12-01T03:08:29Z						biological_process											owl:Class	
GO:0009745	biolink:NamedThing	sucrose mediated signaling	A series of molecular signals mediated by the detection of sucrose.	got7fsn_ti	sucrose mediated signalling													biological_process											owl:Class	
GO:0034162	biolink:NamedThing	toll-like receptor 9 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 9.	got7fsn_ti	toll-like receptor 9 signalling pathway|TLR9 signaling pathway													biological_process											owl:Class	
GO:0007621	biolink:NamedThing	negative regulation of female receptivity	Any process that stops, prevents or reduces the receptiveness of a female to male advances.	got7fsn_ti	inhibition of female receptivity|down-regulation of female receptivity|downregulation of female receptivity|down regulation of female receptivity													biological_process											owl:Class	
GO:0052367	biolink:NamedThing	disruption by host of symbiont cellular component	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	degradation of symbiont cellular component by organism|disassembly by host of symbiont cellular component|catabolism of symbiont structural constituent by organism|catabolism of symbiont cellular component by organism													biological_process											owl:Class	
GO:0018280	biolink:NamedThing	protein S-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine.	got7fsn_ti	protein amino acid S-linked glycosylation													biological_process											owl:Class	
GO:0047176	biolink:NamedThing	beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity	Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose.	got7fsn_ti	1-O-galloyl-beta-D-glucose:1,2,3,6-tetrakis-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity|beta-glucogallin:1,2,3,6-tetra-O-galloylglucose 4-O-galloyltransferase activity|beta-glucogallin-tetragalloylglucose 4-galloyltransferase activity|beta-glucogallin:1,2,3,6-tetra-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity											EC:2.3.1.143|RHEA:19109|KEGG_REACTION:R04498|MetaCyc:2.3.1.143-RXN		molecular_function											owl:Class	
GO:1990089	biolink:NamedThing	response to nerve growth factor	A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.	got7fsn_ti	response to nerve growth factor stimulus						sl	2013-05-06T17:08:47Z						biological_process											owl:Class	
GO:0098610	biolink:NamedThing	adhesion between unicellular organisms	The attachment of two unicellular organisms to each other.	got7fsn_ti	multi-organismal cell-cell adhesion|adhesion between unicellular organisms via cell-wall interaction	https://github.com/geneontology/go-ontology/issues/18814									GO:0098741			biological_process											owl:Class	
GO:0047686	biolink:NamedThing	arylsulfate sulfotransferase activity	Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate.	got7fsn_ti	arylsulfate:phenol sulfotransferase activity|ASST|arylsulfate-phenol sulfotransferase activity|arylsulphate sulphotransferase activity|arylsulfotransferase											RHEA:51072|EC:2.8.2.22|MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0099638	biolink:NamedThing	endosome to plasma membrane protein transport	The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:0090151	biolink:NamedThing	establishment of protein localization to mitochondrial membrane	The directed movement of a protein to a specific location in the mitochondrial membrane.	got7fsn_ti	establishment of protein localization in mitochondrial membrane|establishment of protein localisation in mitochondrial membrane						tb	2009-12-08T03:18:51Z						biological_process											owl:Class	
GO:0000455	biolink:NamedThing	enzyme-directed rRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA.	got7fsn_ti														biological_process											owl:Class	
GO:0070789	biolink:NamedThing	metula development	The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.	got7fsn_ti	development of primary sterigmata						mah	2009-07-08T01:33:46Z						biological_process											owl:Class	
GO:0003325	biolink:NamedThing	pancreatic PP cell development	The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.	got7fsn_ti							dph	2009-11-02T08:25:03Z						biological_process											owl:Class	
GO:0005133	biolink:NamedThing	interferon-gamma receptor binding	Binding to an interferon-gamma receptor.	got7fsn_ti	interferon-gamma receptor ligand|interferon-gamma													molecular_function											owl:Class	
GO:0047600	biolink:NamedThing	abequosyltransferase activity	Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.	got7fsn_ti	CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase activity|trihexose diphospholipid abequosyltransferase activity											RHEA:34183|EC:2.4.1.60|MetaCyc:ABEQUOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0036053	biolink:NamedThing	glomerular endothelium fenestra	A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes.	got7fsn_ti	GEnC fenestration|glomerular endothelial cell fenestration						bf	2011-12-12T10:53:24Z						cellular_component											owl:Class	
GO:0006613	biolink:NamedThing	cotranslational protein targeting to membrane	The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria.	got7fsn_ti	cotranslational membrane targeting|cotranslational protein-membrane targeting|cotranslational protein membrane targeting													biological_process											owl:Class	
GO:0008681	biolink:NamedThing	2-octaprenyl-6-methoxyphenol hydroxylase activity	Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O.	got7fsn_ti												RHEA:29407|MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN		molecular_function											owl:Class	
GO:0003836	biolink:NamedThing	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.	got7fsn_ti	CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyl-transferase activity|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase activity											Reactome:R-HSA-1912378|RHEA:21616|Reactome:R-HSA-9605600|Reactome:R-HSA-981497|Reactome:R-HSA-9603987|EC:2.4.99.4|Reactome:R-HSA-2046285|Reactome:R-HSA-4084984|MetaCyc:2.4.99.4-RXN|Reactome:R-HSA-3656258|Reactome:R-HSA-1022129		molecular_function											owl:Class	
GO:0033727	biolink:NamedThing	aldehyde dehydrogenase (FAD-independent) activity	Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor.	got7fsn_ti	AORDd|aldehyde:acceptor oxidoreductase (FAD-independent) activity|Mop|aldehyde oxidoreductase activity											EC:1.2.99.7|MetaCyc:1.2.99.3-RXN|MetaCyc:1.2.99.7-RXN|MetaCyc:CARBOXYLATE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0050011	biolink:NamedThing	itaconyl-CoA hydratase activity	Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O.	got7fsn_ti	itaconyl coenzyme A hydratase activity|citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)|citramalyl-CoA hydro-lyase activity											EC:4.2.1.56|MetaCyc:ITACONYL-COA-HYDRATASE-RXN|RHEA:13785		molecular_function											owl:Class	
GO:0050889	biolink:NamedThing	determination of stimulus intensity	The determination of the perceived strength of a sensory stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0000246	biolink:NamedThing	delta24(24-1) sterol reductase activity	Catalysis of the reaction: ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H(+) + NADPH.	got7fsn_ti	C-24(28) sterol reductase activity|sterol delta-24(28) methylene reductase activity|sterol delta24(28)-reductase activity|sterol Delta(24(28))-reductase activity|ergosterol:NADP+ delta24(241)-oxidoreductase activity|sterol delta-24(28) reductase activity|sterol Delta(24(28))-methylene reductase activity|delta24(241)-sterol reductase activity|D24(24-1)-sterol reductase activity|sterol delta24(28)-methylene reductase activity											MetaCyc:1.3.1.71-RXN|RHEA:18501|KEGG_REACTION:R05641|EC:1.3.1.71		molecular_function											owl:Class	
GO:0044600	biolink:NamedThing	protein guanylyltransferase activity	Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins.	got7fsn_ti							jl	2012-05-01T04:00:34Z						molecular_function											owl:Class	
GO:0070285	biolink:NamedThing	pigment cell development	The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0047994	biolink:NamedThing	hydroxymethylglutaryl-CoA hydrolase activity	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H(2)O = 3-hydroxy-3-methylglutarate + CoA + H(+).	got7fsn_ti	beta-hydroxy-beta-methylglutaryl coenzyme A deacylase activity|beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase activity|hydroxymethylglutaryl coenzyme A deacylase activity|hydroxymethylglutaryl coenzyme A hydrolase activity|3-hydroxy-3-methylglutaryl-CoA hydrolase activity											EC:3.1.2.5|KEGG_REACTION:R02083|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-HYDROLASE-RXN|RHEA:16305		molecular_function											owl:Class	
GO:0047444	biolink:NamedThing	N-acylneuraminate-9-phosphate synthase activity	Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.	got7fsn_ti	N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase activity|N-acetylneuraminate 9-phosphate lyase activity|phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase activity|N-acetylneuraminic acid phosphate synthase activity|N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating) activity|sialic acid 9-phosphate synthetase activity|N-acetylneuraminate 9-phosphate synthetase activity										GO:0019007	MetaCyc:4.1.3.20-RXN|EC:2.5.1.57|RHEA:13421|Reactome:R-HSA-4084976		molecular_function											owl:Class	
GO:0043082	biolink:NamedThing	megagametophyte egg cell nucleus	The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo.	got7fsn_ti														cellular_component											owl:Class	
GO:0098832	biolink:NamedThing	peri-centrosomal recycling endosome	A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes.	got7fsn_ti														cellular_component											owl:Class	
GO:0061373	biolink:NamedThing	mammillary axonal complex development	The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.	got7fsn_ti							dph	2010-11-09T08:49:59Z						biological_process											owl:Class	
GO:0033704	biolink:NamedThing	3beta-hydroxy-5alpha-steroid dehydrogenase activity	Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH.	got7fsn_ti	3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase activity											MetaCyc:1.1.1.278-RXN|EC:1.1.1.278|KEGG_REACTION:R07138|RHEA:18137		molecular_function											owl:Class	
GO:0045062	biolink:NamedThing	extrathymic T cell selection	The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus.	got7fsn_ti	extrathymic T lymphocyte selection|extrathymic T-cell selection|extrathymic T-lymphocyte selection													biological_process											owl:Class	
GO:0103093	biolink:NamedThing	methylthioalkylmalate dehydrogenase activity	Catalysis of the reaction: 3-(7'-methylthio)heptylmalate <=> H+ + 2-oxo-10-methylthiodecanoate + carbon dioxide.	got7fsn_ti												MetaCyc:RXNQT-4178		molecular_function											owl:Class	
GO:0030353	biolink:NamedThing	fibroblast growth factor receptor antagonist activity	Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist.	got7fsn_ti	FGFR antagonist activity|FGF receptor antagonist activity													molecular_function											owl:Class	
GO:0036371	biolink:NamedThing	protein localization to T-tubule	A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.	got7fsn_ti	protein localisation to T-tubule|protein localization to transverse tubule|protein localization to T tubule						bf	2012-10-08T17:10:29Z						biological_process											owl:Class	
GO:0004348	biolink:NamedThing	glucosylceramidase activity	Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.	got7fsn_ti	acid beta-glucosidase activity|glucocerebrosidase activity|psychosine hydrolase activity|glucosylsphingosine beta-D-glucosidase activity|beta-glucocerebrosidase activity|glucosphingosine glucosylhydrolase activity|beta-D-glucocerebrosidase activity|glucosylsphingosine beta-glucosidase activity|GlcCer-beta-glucosidase activity|ceramide glucosidase activity|glucosylcerebrosidase activity|beta-glucosylceramidase activity|D-glucosyl-N-acylsphingosine glucohydrolase activity											Reactome:R-HSA-1861789|MetaCyc:GLUCOSYLCERAMIDASE-RXN|Reactome:R-HSA-1861788|Reactome:R-HSA-1605591|RHEA:13269|EC:3.2.1.45		molecular_function											owl:Class	
GO:0072162	biolink:NamedThing	metanephric mesenchymal cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-02-26T01:35:00Z						biological_process											owl:Class	
GO:0072161	biolink:NamedThing	mesenchymal cell differentiation involved in kidney development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-02-26T01:31:49Z						biological_process											owl:Class	
GO:0072196	biolink:NamedThing	proximal/distal pattern formation involved in pronephric nephron development	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.	got7fsn_ti	pronephros proximal/distal pattern formation						mah	2010-03-01T02:11:07Z						biological_process											owl:Class	
GO:0021719	biolink:NamedThing	superior olivary nucleus morphogenesis	The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	got7fsn_ti	superior olive morphogenesis													biological_process											owl:Class	
GO:0019653	biolink:NamedThing	anaerobic purine nucleobase catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.	got7fsn_ti	anaerobic purine base catabolism|anaerobic purine catabolic process|purine fermentation|purine base fermentation|anaerobic purine base catabolic process											MetaCyc:PWY-5044|MetaCyc:PWY-5497|MetaCyc:P164-PWY		biological_process											owl:Class	
GO:0006145	biolink:NamedThing	purine nucleobase catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.	got7fsn_ti	purine base catabolic process|purine base degradation|purine base breakdown|purine base catabolism													biological_process											owl:Class	
GO:0018136	biolink:NamedThing	peptidyl-thiazoline dehydrogenase activity	Catalysis of the reduction of a peptide-linked thiazoline to thiazole.	got7fsn_ti														molecular_function											owl:Class	
GO:0102400	biolink:NamedThing	dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> 2 S-adenosyl-L-homocysteine  + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + 2 H+.	got7fsn_ti												MetaCyc:RXN-13667		molecular_function											owl:Class	
GO:0102727	biolink:NamedThing	3beta-hydroxysteroid dehydrogenase activity	Catalysis of the reaction: campest-4-en-3beta-ol + NAD = campest-4-en-3-one + NADH + H+.	got7fsn_ti												MetaCyc:RXN-710		molecular_function											owl:Class	
GO:0030734	biolink:NamedThing	polysaccharide O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units.	got7fsn_ti	S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase activity|polysaccharide methyltransferase activity|acylpolysacharide 6-methyltransferase activity											MetaCyc:POLYSACCHARIDE-O-METHYLTRANSFERASE-RXN|EC:2.1.1.18		molecular_function											owl:Class	
GO:0050533	biolink:NamedThing	5-phytase activity	Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate.	got7fsn_ti	myo-inositol-hexakisphosphate 5-phosphohydrolase activity											RHEA:13001|EC:3.1.3.72|MetaCyc:3.1.3.72-RXN		molecular_function											owl:Class	
GO:0048560	biolink:NamedThing	establishment of anatomical structure orientation	The process that determines the orientation of an anatomical structure with reference to an axis.	got7fsn_ti														biological_process											owl:Class	
GO:0140355	biolink:NamedThing	cargo receptor ligand activity	The activity of a gene product that interacts with a cargo receptor and initiates endocytosis.	got7fsn_ti	cargo						pg	2019-05-27T09:56:50Z						molecular_function											owl:Class	
GO:0050124	biolink:NamedThing	N-acylneuraminate-9-phosphatase activity	Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate.	got7fsn_ti	N-acylneuraminic (sialic) acid 9-phosphatase activity|N-acylneuraminate-9-phosphate phosphohydrolase activity|acylneuraminate 9-phosphatase activity|N-acylneuraminic acid 9-phosphate phosphatase activity											EC:3.1.3.29|Reactome:R-HSA-4084989|MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN|RHEA:13057		molecular_function											owl:Class	
GO:0030014	biolink:NamedThing	CCR4-NOT complex	The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.	got7fsn_ti														cellular_component											owl:Class	
GO:0045523	biolink:NamedThing	interleukin-27 receptor binding	Binding to an interleukin-27 receptor.	got7fsn_ti	interleukin-27 receptor ligand|IL-27													molecular_function											owl:Class	
GO:0097294	biolink:NamedThing	'de novo' XMP biosynthetic process	The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.	got7fsn_ti	'de novo' XMP synthesis|'de novo' XMP anabolism|'de novo' XMP biosynthesis|'de novo' XMP formation						pr	2012-04-26T09:57:49Z						biological_process											owl:Class	
GO:0097293	biolink:NamedThing	XMP biosynthetic process	The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.	got7fsn_ti	XMP biosynthesis|XMP formation|XMP synthesis|XMP anabolism						pr	2012-04-26T09:54:13Z						biological_process											owl:Class	
GO:0004462	biolink:NamedThing	lactoylglutathione lyase activity	Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.	got7fsn_ti	(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity|(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)|aldoketomutase activity|ketone-aldehyde mutase activity|glyoxalase I activity|glyoxylase I|methylglyoxalase activity											Reactome:R-HSA-5694071|MetaCyc:GLYOXI-RXN|RHEA:19069|KEGG_REACTION:R02530|EC:4.4.1.5		molecular_function											owl:Class	
GO:0102952	biolink:NamedThing	UDP-glucose:coniferaldehyde 4-beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + coniferyl aldehyde = H+ + coniferaldehyde glucoside + UDP.	got7fsn_ti												RHEA:57708|MetaCyc:RXN-91		molecular_function											owl:Class	
GO:0007181	biolink:NamedThing	transforming growth factor beta receptor complex assembly	The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex.	got7fsn_ti	TGF-beta receptor complex assembly|TGFbeta receptor complex assembly|TGF-beta:type II receptor:type I receptor complex assembly													biological_process											owl:Class	
GO:0047880	biolink:NamedThing	erythrulose reductase activity	Catalysis of the reaction: D-threitol + NADP(+) = D-erythrulose + H(+) + NADPH.	got7fsn_ti	D-erythrulose reductase activity|erythritol:NADP+ oxidoreductase activity											EC:1.1.1.162|KEGG_REACTION:R08573|MetaCyc:ERYTHRULOSE-REDUCTASE-RXN|RHEA:18005		molecular_function											owl:Class	
GO:0018289	biolink:NamedThing	molybdenum incorporation into metallo-sulfur cluster	The incorporation of molybdenum into a metallo-sulfur cluster.	got7fsn_ti	molybdenum incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0102621	biolink:NamedThing	emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity	Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ <=> 14,15-epoxyemindole-SB + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15496		molecular_function											owl:Class	
GO:0002125	biolink:NamedThing	maternal aggressive behavior	Aggressive behavior of a female to protect her offspring from a threat.	got7fsn_ti	maternal aggression				Paternal aggression also exists. Serves to protect the offspring from intruders.									biological_process											owl:Class	
GO:0010673	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.	got7fsn_ti	positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|activation of meiosis by positive regulation of transcription from RNA polymerase II promoter|up regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|upregulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|stimulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter, meiotic						dgf	2012-05-01T08:40:11Z			GO:1900476			biological_process											owl:Class	
GO:0102803	biolink:NamedThing	thebane O-demethylase activity	Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-8149|EC:1.14.11.32		molecular_function											owl:Class	
GO:0010158	biolink:NamedThing	abaxial cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0042711	biolink:NamedThing	maternal behavior	Female behaviors associated with the care and rearing of offspring.	got7fsn_ti	maternal behaviour													biological_process											owl:Class	
GO:0102086	biolink:NamedThing	N-vanillate-L-glutamate synthetase activity	Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP <=> H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10885		molecular_function											owl:Class	
GO:0021505	biolink:NamedThing	neural fold folding	The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.	got7fsn_ti														biological_process											owl:Class	
GO:0047154	biolink:NamedThing	methylmalonyl-CoA carboxytransferase activity	Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA.	got7fsn_ti	(S)-methylmalonyl-CoA:pyruvate carboxyltransferase activity|methylmalonyl coenzyme A carboxyltransferase activity|transcarboxylase activity|(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate|(S)-methylmalonyl-CoA:pyruvate carboxytransferase activity|methylmalonyl-CoA carboxyltransferase activity|(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase activity|methylmalonyl-CoA transcarboxylase activity|oxalacetic transcarboxylase activity											MetaCyc:2.1.3.1-RXN|UM-BBD_reactionID:r0923|RHEA:20764|EC:2.1.3.1		molecular_function											owl:Class	
GO:0048206	biolink:NamedThing	vesicle targeting, cis-Golgi to rough endoplasmic reticulum	The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER.	got7fsn_ti	cis-Golgi to rough endoplasmic reticulum targeting|cis-Golgi to rough ER targeting|vesicle targeting, cis-Golgi to rough endoplasmic reticulum|vesicle targeting, cis-Golgi to rough ER													biological_process											owl:Class	
GO:0072086	biolink:NamedThing	specification of loop of Henle identity	The process in which the loop of Henle of the kidney nephron acquires its identity.	got7fsn_ti	specification of intermediate tubule identity						mah	2010-02-01T02:49:35Z			GO:0072083			biological_process											owl:Class	
GO:0031411	biolink:NamedThing	gas vesicle	An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations.	got7fsn_ti	gas vacuole				Note that although this organelle is commonly referred to as a 'vesicle' or 'vacuole' in the literature, it is not surrounded by a membrane.									cellular_component											owl:Class	
GO:0048520	biolink:NamedThing	positive regulation of behavior	Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.	got7fsn_ti	stimulation of behavior|activation of behavior|up-regulation of behavior|upregulation of behavior|up regulation of behavior													biological_process											owl:Class	
GO:1990046	biolink:NamedThing	stress-induced mitochondrial fusion	Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.	got7fsn_ti	stress-induced mitochondrial hyperfusion|mitochondrial fusion in response to stress|SIMH						pr	2013-02-15T16:01:55Z						biological_process											owl:Class	
GO:0008053	biolink:NamedThing	mitochondrial fusion	Merging of two or more mitochondria within a cell to form a single compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0034256	biolink:NamedThing	chlorophyll(ide) b reductase activity	Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+.	got7fsn_ti	Chl b reductase activity|chlorophyllide b reductase activity|chlorophyll b reductase activity											MetaCyc:RXN-7678|EC:1.1.1.294		molecular_function											owl:Class	
GO:0071821	biolink:NamedThing	FANCM-MHF complex	A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes.	got7fsn_ti							mah	2010-09-07T12:08:38Z						cellular_component											owl:Class	
GO:0106229	biolink:NamedThing	histone glutaryltransferase activity	Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone.	got7fsn_ti							hjd	2019-10-17T19:01:48Z						molecular_function											owl:Class	
GO:0019643	biolink:NamedThing	reductive tricarboxylic acid cycle	A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate.	got7fsn_ti	reductive carboxylate cycle|reductive citric acid pathway|reductive TCA cycle|reductive Kreb's cycle|reductive carboxylic acid cycle										GO:0019644	MetaCyc:REDCITCYC|MetaCyc:P23-PWY		biological_process											owl:Class	
GO:0018030	biolink:NamedThing	peptidyl-lysine N6-myristoyltransferase activity	Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0018053	biolink:NamedThing	C-terminal peptidyl-valine amidation	The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0100		biological_process											owl:Class	
GO:0052042	biolink:NamedThing	positive regulation by symbiont of host programmed cell death	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of host programmed cell death|upregulation by symbiont of host programmed cell death|induction of non-apoptotic programmed cell death by other organism|pathogenesis|activation by organism of programmed cell death in other organism during symbiotic interaction|induction by organism of programmed cell death in other organism involved in symbiotic interaction|induction by symbiont of host programmed cell death|induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|enhancement of host programmed cell death|activation by organism of non-apoptotic programmed cell death in other organism|stimulation by symbiont of host programmed cell death|induction by organism of programmed cell death in other organism during symbiotic interaction|activation by symbiont of host programmed cell death|enhancement of host programmed cell death by organism|positive regulation by symbiont of host non-apoptotic programmed cell death										GO:0012504|GO:0052400|GO:0052044|GO:0052397|GO:0052045|GO:0052153			biological_process											owl:Class	
GO:0102561	biolink:NamedThing	D-ribose 2,5-bisphosphate 2-phosphohydrolase activity	Catalysis of the reaction: H2O + D-ribofuranose 2,5-bisphosphate <=> hydrogenphosphate + D-ribofuranose 5-phosphate.	got7fsn_ti												RHEA:41616|EC:3.1.4.57|MetaCyc:RXN-14996		molecular_function											owl:Class	
GO:0043053	biolink:NamedThing	dauer entry	Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development.	got7fsn_ti	nematode entry into dormancy													biological_process											owl:Class	
GO:0140074	biolink:NamedThing	cardiac endothelial to mesenchymal transition	A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes.	got7fsn_ti	EndoMT|EndMT						pg	2017-07-21T09:39:49Z						biological_process											owl:Class	
GO:0048762	biolink:NamedThing	mesenchymal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.	got7fsn_ti														biological_process											owl:Class	
GO:0052858	biolink:NamedThing	peptidyl-lysine acetyltransferase activity	Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.	got7fsn_ti	peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor|acetyl-phosphate:peptidyl-L-lysine N6-acetyltransferase activity|peptidyl-lysine N6-acetyltransferase activity|acetyl-phosphate:peptidyl-L-lysine 6-N-acetyltransferase activity|peptidyl-lysine N(6)-acetyltransferase activity													molecular_function											owl:Class	
GO:0031311	biolink:NamedThing	intrinsic component of contractile vacuolar membrane	The component of the contractile vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to contractile vacuolar membrane													cellular_component											owl:Class	
GO:0031094	biolink:NamedThing	platelet dense tubular network	A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.	got7fsn_ti														cellular_component											owl:Class	
GO:2000610	biolink:NamedThing	negative regulation of thyroid hormone generation	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.	got7fsn_ti							yaf	2011-04-18T10:12:19Z						biological_process											owl:Class	
GO:0050415	biolink:NamedThing	formimidoylglutamase activity	Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.	got7fsn_ti	N-formiminoglutamate hydrolase activity|formiminoglutamase activity|N-formimidoyl-L-glutamate formimidoylhydrolase activity|formiminoglutamate hydrolase activity|N-formimino-L-glutamate formiminohydrolase activity											MetaCyc:FORMIMINOGLUTAMASE-RXN|KEGG_REACTION:R02285|EC:3.5.3.8|RHEA:22492		molecular_function											owl:Class	
GO:0071732	biolink:NamedThing	cellular response to nitric oxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.	got7fsn_ti							mah	2010-03-17T04:12:52Z						biological_process											owl:Class	
GO:0045437	biolink:NamedThing	uridine nucleosidase activity	Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil.	got7fsn_ti	uridine ribohydrolase activity|uridine hydrolase activity											MetaCyc:URIDINE-NUCLEOSIDASE-RXN|RHEA:15577|KEGG_REACTION:R01080|EC:3.2.2.3		molecular_function											owl:Class	
GO:0003055	biolink:NamedThing	circadian regulation of heart rate by the suprachiasmatic nucleus	The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.	got7fsn_ti	SCN regulation of heart rate|circadian regulation of heart contraction rate by the suprachiasmatic nucleus|master pacemaker clock regulation of heart rate													biological_process											owl:Class	
GO:0018598	biolink:NamedThing	hydroxymethylsilanetriol oxidase activity	Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol.	got7fsn_ti												UM-BBD_reactionID:r0641		molecular_function											owl:Class	
GO:0034642	biolink:NamedThing	mitochondrion migration along actin filament	The directed movement of a mitochondrion along a microfilament, mediated by motor proteins.	got7fsn_ti	mitochondrial migration, actin-mediated|mitochondrial migration along microfilament|mitochondrion migration along microfilament|mitochondrion transport along actin filament|mitochondrial migration along actin filament													biological_process											owl:Class	
GO:0042121	biolink:NamedThing	alginic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).	got7fsn_ti	alginic acid synthesis|alginate biosynthetic process|alginic acid formation|alginate biosynthesis|alginic acid anabolism|alginic acid biosynthesis													biological_process											owl:Class	
GO:0010493	biolink:NamedThing	Lewis a epitope biosynthetic process	The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.	got7fsn_ti	LE A biosynthetic process													biological_process											owl:Class	
GO:0055043	biolink:NamedThing	5-oxovalerate dehydrogenase activity	Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+.	got7fsn_ti														molecular_function											owl:Class	
GO:0019186	biolink:NamedThing	acyl-CoA N-acyltransferase activity	Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0140426	biolink:NamedThing	PAMP-triggered immunity signalling pathway	Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands to activate a plant innate immune response. PAMP-triggered immunity PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.	got7fsn_ti	pathogen-associated molecular pattern signalling|PTI signalling|MAMP-triggered immunity signalling	https://github.com/geneontology/go-ontology/issues/18588					pg	2020-02-11T11:08:57Z						biological_process											owl:Class	
GO:0004583	biolink:NamedThing	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity	Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide.	got7fsn_ti												Reactome:R-HSA-446194|MetaCyc:RXN-5472|Reactome:R-HSA-446189|Reactome:R-HSA-446202|Reactome:R-HSA-4724330|Reactome:R-HSA-4724291		molecular_function											owl:Class	
GO:0047743	biolink:NamedThing	chlordecone reductase activity	Catalysis of the reaction: chlordecone alcohol + NADP(+) = chlordecone + H(+) + NADPH.	got7fsn_ti	CDR activity|chlordecone-alcohol:NADP+ 2-oxidoreductase activity											RHEA:14401|MetaCyc:CHLORDECONE-REDUCTASE-RXN|EC:1.1.1.225|KEGG_REACTION:R03716		molecular_function											owl:Class	
GO:0061757	biolink:NamedThing	leukocyte adhesion to arterial endothelial cell	The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules.	got7fsn_ti							dph	2016-02-29T16:49:38Z						biological_process											owl:Class	
GO:0035661	biolink:NamedThing	MyD88-dependent toll-like receptor 2 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.	got7fsn_ti	MyD88-dependent TLR2 signaling pathway|MyD88-dependent toll-like receptor 2 signalling pathway						bf	2011-02-01T10:11:01Z						biological_process											owl:Class	
GO:0034134	biolink:NamedThing	toll-like receptor 2 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 2.	got7fsn_ti	TLR2 signaling pathway|toll-like receptor 2 signalling pathway													biological_process											owl:Class	
GO:0006977	biolink:NamedThing	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.	got7fsn_ti	positive regulation of cell cycle arrest by p53-mediated DNA damage response													biological_process											owl:Class	
GO:0097715	biolink:NamedThing	cellular response to viscosity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.	got7fsn_ti							pr	2016-08-23T14:34:05Z						biological_process											owl:Class	
GO:0097714	biolink:NamedThing	response to viscosity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.	got7fsn_ti							pr	2016-08-23T14:32:46Z						biological_process											owl:Class	
GO:1990333	biolink:NamedThing	mitotic checkpoint complex, CDC20-MAD2 subcomplex	A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.	got7fsn_ti	CDC20-MAD2 complex				An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay).		bhm	2014-03-17T14:11:35Z						cellular_component											owl:Class	
GO:0002306	biolink:NamedThing	CD4-positive gamma-delta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	got7fsn_ti	CD4-positive, gamma-delta intraepithelial T-lymphocyte differentiation|CD4-positive, gamma-delta intraepithelial T-cell differentiation|CD4-positive, gamma-delta intraepithelial T cell development|CD4-positive, gamma-delta intraepithelial T lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0061175	biolink:NamedThing	type II terminal bouton	Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.	got7fsn_ti	type II terminal button						dph	2010-07-13T09:18:01Z						cellular_component											owl:Class	
GO:0098540	biolink:NamedThing	lumenal side of trans-Golgi network transport vesicle membrane	The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the lumen.	got7fsn_ti	internal side of trans-Golgi network transport vesicle membrane						dos	2013-10-24T11:55:02Z						cellular_component											owl:Class	
GO:0098538	biolink:NamedThing	lumenal side of transport vesicle membrane	The side (leaflet) of the transport vesicle membrane that faces the lumen.	got7fsn_ti	internal side of transport vesicle membrane						dos	2013-10-24T11:43:55Z						cellular_component											owl:Class	
GO:0050527	biolink:NamedThing	poly(3-hydroxyoctanoate) depolymerase activity	Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5.	got7fsn_ti	poly(HA) depolymerase activity|poly{oxycarbonyl[(R)-2-pentylethylene]} hydrolase activity|PHO depolymerase activity|PHA depolymerase activity|poly((R)-3-hydroxyoctanoate) hydrolase activity|poly(HA(MCL)) depolymerase activity|poly(3HO) depolymerase activity|poly[(R)-3-hydroxyoctanoate] hydrolase activity|poly(HAMCL) depolymerase activity|poly[(R)-hydroxyalkanoic acid] depolymerase|poly((R)-hydroxyalkanoic acid) depolymerase activity											MetaCyc:3.1.1.76-RXN|EC:3.1.1.76		molecular_function											owl:Class	
GO:0038028	biolink:NamedThing	insulin receptor signaling pathway via phosphatidylinositol 3-kinase	The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade.	got7fsn_ti	insulin receptor signaling via PI3K|insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade|insulin receptor signaling pathway via PI3K cascade|insulin receptor signalling pathway via phosphatidylinositol 3-kinase cascade						bf	2011-09-08T10:35:14Z						biological_process											owl:Class	
GO:0140585	biolink:NamedThing	promoter-enhancer loop anchoring activity	Bridging together two cis-regulatory elements, colloquially referred to as promoters and/or enhancers, holding two loop anchors together to maintain a chromatin loop.	got7fsn_ti	enhancer-promoter loop anchoring activity	https://github.com/geneontology/go-ontology/issues/20204			Note that GO does not separately defines enhancers, since this concept is very close to that of cis-regulatory elements. However the literature refers to 'promoter-enhancer loops' to describe loops that bring together cis-regulatory elements. Note also that while SO defines 'promoter' as the core promoter, here it is used to mean a cis-regulatory element.		pg	2021-02-04T14:50:04Z						molecular_function											owl:Class	
GO:0047883	biolink:NamedThing	ethanolamine oxidase activity	Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2.	got7fsn_ti	ethanolamine:oxygen oxidoreductase (deaminating)											MetaCyc:ETHANOLAMINE-OXIDASE-RXN|RHEA:18581|EC:1.4.3.8		molecular_function											owl:Class	
GO:0047291	biolink:NamedThing	lactosylceramide alpha-2,3-sialyltransferase activity	Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.	got7fsn_ti	ganglioside GM3 synthase activity|GM3 synthase activity|CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase|CMP-acetylneuraminic acid:lactosylceramide sialyltransferase activity|SAT 1|GM3 synthetase activity|CMP-acetylneuraminate-lactosylceramide-sialyltransferase|ganglioside GM3 synthetase activity|CMP-sialic acid:lactosylceramide-sialyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide alpha2,3- sialyltransferase activity											MetaCyc:2.4.99.9-RXN|EC:2.4.99.9|RHEA:18417		molecular_function											owl:Class	
GO:0036098	biolink:NamedThing	male germ-line stem cell population maintenance	The process by which an organism or tissue maintains a population of male germ-line stem cells.	got7fsn_ti							bf	2012-01-26T01:58:10Z						biological_process											owl:Class	
GO:0030718	biolink:NamedThing	germ-line stem cell population maintenance	Any process by which an organism or tissue maintains a population of germ-line stem cells.	got7fsn_ti														biological_process											owl:Class	
GO:0016456	biolink:NamedThing	X chromosome located dosage compensation complex, transcription activating	An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster.	got7fsn_ti	dosage compensation complex													cellular_component											owl:Class	
GO:0046557	biolink:NamedThing	glucan endo-1,6-beta-glucosidase activity	Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.	got7fsn_ti	1,6-beta-D-glucan glucanohydrolase activity|beta-1->6-glucan hydrolase activity|endo-1,6-beta-glucanase activity|endo-1,6-beta-D-glucanase activity|beta-1,6-glucanase activity|beta-1,6-glucanase-pustulanase activity|beta-1,6-glucan 6-glucanohydrolase activity|endo-beta-1,6-glucanase activity|endo-(1->6)-beta-D-glucanase activity|beta-1,6-glucan hydrolase activity|endo-(1,6)-beta-D-glucanase activity											EC:3.2.1.75|MetaCyc:3.2.1.75-RXN		molecular_function											owl:Class	
GO:0047753	biolink:NamedThing	choline-sulfatase activity	Catalysis of the reaction: choline sulfate + H(2)O = choline + H(+) + sulfate.	got7fsn_ti	choline-sulphatase activity|choline-sulfate sulfohydrolase activity											KEGG_REACTION:R01028|EC:3.1.6.6|MetaCyc:CHOLINE-SULFATASE-RXN|RHEA:20820		molecular_function											owl:Class	
GO:0051800	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidylinositol-4-phosphate + phosphate.	got7fsn_ti	PTEN activity											Reactome:R-HSA-1676204|Reactome:R-HSA-1676149		molecular_function											owl:Class	
GO:0060156	biolink:NamedThing	milk ejection reflex	A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness.	got7fsn_ti	milk ejection													biological_process											owl:Class	
GO:0071112	biolink:NamedThing	alpha4-beta4 integrin-EMILIN-1 complex	A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN).	got7fsn_ti	ITGA4-ITGB4-EMILIN1 complex						mah	2009-11-13T02:17:11Z						cellular_component											owl:Class	
GO:0103077	biolink:NamedThing	quercetin 3-glucoside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: quercetin-3-glucoside + UDP-L-rhamnose <=> quercetin-3-O-glucoside-7-O-rhamnoside + UDP.	got7fsn_ti												MetaCyc:RXNQT-4161|RHEA:61188		molecular_function											owl:Class	
GO:0035983	biolink:NamedThing	response to trichostatin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.	got7fsn_ti							bf	2011-08-23T01:48:01Z						biological_process											owl:Class	
GO:1990757	biolink:NamedThing	ubiquitin ligase activator activity	Binds to and increases the activity of a ubiquitin ligase.	got7fsn_ti	mitotic anaphase-promoting complex activator activity						vw	2015-06-01T08:53:04Z			GO:0061636			molecular_function											owl:Class	
GO:0075203	biolink:NamedThing	positive regulation of penetration hypha formation	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont penetration hypha formation for entry into host	https://github.com/geneontology/go-ontology/issues/21121			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0000995	biolink:NamedThing	RNA polymerase III general transcription initiation factor activity	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III.	got7fsn_ti	core RNA polymerase III binding transcription factor activity|RNA polymerase III transcription factor activity, sequence-specific DNA binding|transcription factor activity, core RNA polymerase III binding|RNA polymerase III general initiation factor activity|sequence-specific DNA binding RNA polymerase III transcription factor activity	https://github.com/geneontology/go-ontology/issues/15789|https://github.com/geneontology/go-ontology/issues/20253					krc	2010-08-23T03:41:48Z			GO:0001034			molecular_function											owl:Class	
GO:0033443	biolink:NamedThing	AAA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AAA codon.	got7fsn_ti	lysine tRNA				Note that in the standard genetic code, AAA codes for lysine.									molecular_function											owl:Class	
GO:0070150	biolink:NamedThing	mitochondrial glycyl-tRNA aminoacylation	The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:1990785	biolink:NamedThing	response to water-immersion restraint stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.	got7fsn_ti	response to immobilization stress combined with water immersion						sl	2015-06-24T18:27:28Z						biological_process											owl:Class	
GO:0021524	biolink:NamedThing	visceral motor neuron differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0044803	biolink:NamedThing	multi-organism membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism.	got7fsn_ti							jl	2013-09-10T15:11:41Z						biological_process											owl:Class	
GO:0031052	biolink:NamedThing	chromosome breakage	Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.	got7fsn_ti	establishment or maintenance of heterochromatin architecture				Note that this term refers to breakage of chromosomes during normal DNA rearrangements characteristic of ciliates; it is not to be used for DNA damage or other abnormal occurrences.									biological_process											owl:Class	
GO:0061810	biolink:NamedThing	NAD glycohydrolase activity	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose without proceeding through a cyclic ADP-ribose intermediate.	got7fsn_ti							dph	2016-11-11T13:18:54Z				Reactome:R-HSA-9637699|EC:3.2.2.5		molecular_function											owl:Class	
GO:0033996	biolink:NamedThing	levan fructotransferase (DFA-IV-forming) activity	Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.	got7fsn_ti	2,6-beta-D-fructan lyase (di-beta-D-fructofuranose-2,6':2',6-dianhydride-forming) activity|levan fructotransferase activity|2,6-beta-D-fructan D-fructosyl-D-fructosyltransferase (forming di-beta-D-fructofuranose 2,6':2',6-dianhydride) activity											MetaCyc:4.2.2.16-RXN|EC:4.2.2.16		molecular_function											owl:Class	
GO:0099559	biolink:NamedThing	maintenance of alignment of postsynaptic density and presynaptic active zone	The process by which alignment between postsynaptic density and presynaptic active zone is maintained.	got7fsn_ti														biological_process											owl:Class	
GO:1901098	biolink:NamedThing	positive regulation of autophagosome maturation	Any process that activates or increases the frequency, rate or extent of autophagosome maturation.	got7fsn_ti	up-regulation of autolysosome formation|up-regulation of autophagosome maturation|upregulation of autophagosome maturation|up-regulation of autophagic vacuole maturation|up regulation of fusion of autophagosome with lysosome|activation of autophagic vacuole maturation|positive regulation of amphisome-lysosome fusion|upregulation of autolysosome formation|upregulation of fusion of autophagosome with lysosome|upregulation of autophagic vacuole fusion|up regulation of autophagosome maturation|activation of autophagic vacuole fusion|upregulation of autophagic vacuole maturation|activation of autophagosome maturation|activation of autolysosome formation|upregulation of amphisome-lysosome fusion|positive regulation of autophagic vacuole fusion|positive regulation of fusion of autophagosome with lysosome|activation of fusion of autophagosome with lysosome|positive regulation of autophagosome maturation|up-regulation of fusion of autophagosome with lysosome|up regulation of amphisome-lysosome fusion|up regulation of autophagic vacuole fusion|positive regulation of autolysosome formation|up regulation of autolysosome formation|activation of amphisome-lysosome fusion|positive regulation of autophagosome fusion|up-regulation of amphisome-lysosome fusion|up-regulation of autophagic vacuole fusion|up regulation of autophagic vacuole maturation						lb	2012-07-10T07:22:34Z			GO:1902454			biological_process											owl:Class	
GO:0033280	biolink:NamedThing	response to vitamin D	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.	got7fsn_ti	response to cholecalciferol|response to calciferol|response to ergocalciferol													biological_process											owl:Class	
GO:0060444	biolink:NamedThing	branching involved in mammary gland duct morphogenesis	The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	got7fsn_ti	mammary gland branching morphogenesis													biological_process											owl:Class	
GO:0051007	biolink:NamedThing	squalene-hopene cyclase activity	Catalysis of the reaction: squalene = hop-22(29)-ene.	got7fsn_ti	squalene mutase (cyclizing)|squalene:hopene cyclase activity											EC:5.4.99.17|MetaCyc:5.4.99.17-RXN|RHEA:17637		molecular_function											owl:Class	
GO:0018787	biolink:NamedThing	4-chlorobenzoyl-CoA dehalogenase activity	Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride.	got7fsn_ti	4-chlorobenzoyl CoA chlorohydrolase activity											UM-BBD_enzymeID:e0113|MetaCyc:3.8.1.7-RXN|RHEA:14853|EC:3.8.1.7		molecular_function											owl:Class	
GO:0046332	biolink:NamedThing	SMAD binding	Binding to a SMAD signaling protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0070748	biolink:NamedThing	interleukin-35 receptor binding	Binding to an interleukin-35 receptor.	got7fsn_ti	interleukin-35 receptor ligand|IL-35						mah	2009-06-23T01:21:54Z						molecular_function											owl:Class	
GO:0102425	biolink:NamedThing	myricetin 3-O-glucosyltransferase activity	Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP.	got7fsn_ti												MetaCyc:RXN-13822|EC:2.4.1.91		molecular_function											owl:Class	
GO:0102430	biolink:NamedThing	alpha-linolenate delta5 desaturase activity	Catalysis of the reaction: alpha-linolenate + O2 + a reduced electron acceptor = coniferonate + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												RHEA:38039|MetaCyc:RXN-13857		molecular_function											owl:Class	
GO:0009368	biolink:NamedThing	endopeptidase Clp complex	A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.	got7fsn_ti														cellular_component											owl:Class	
GO:0070940	biolink:NamedThing	dephosphorylation of RNA polymerase II C-terminal domain	The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.	got7fsn_ti	generation of II(A) form of RNA polymerase II|CTD domain dephosphorylation of RNA polymerase II|generation of hypophosphorylated CTD of RNA polymerase II						mah	2009-09-29T04:34:14Z						biological_process											owl:Class	
GO:1902533	biolink:NamedThing	positive regulation of intracellular signal transduction	Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.	got7fsn_ti	up-regulation of signal transduction via intracellular signaling cascade|upregulation of signal transduction via intracellular signaling cascade|activation of intracellular signaling pathway|upregulation of intracellular signaling pathway|activation of intracellular signaling cascade|positive regulation of intracellular signaling chain|activation of intracellular signal transduction pathway|up-regulation of intracellular signal transduction pathway|activation of intracellular signal transduction|up regulation of intracellular signaling pathway|up regulation of signal transmission via intracellular cascade|positive regulation of intracellular signaling cascade|up-regulation of signal transmission via intracellular cascade|upregulation of intracellular signaling chain|activation of intracellular signaling chain|up-regulation of intracellular signaling pathway|up regulation of intracellular signal transduction pathway|positive regulation of signal transduction via intracellular signaling cascade|upregulation of intracellular signaling cascade|up-regulation of intracellular signaling cascade|positive regulation of signal transmission via intracellular cascade|up regulation of intracellular signal transduction|up regulation of intracellular signaling cascade|up regulation of intracellular signaling chain|upregulation of signal transmission via intracellular cascade|up-regulation of intracellular signal transduction|upregulation of intracellular signal transduction pathway|positive regulation of intracellular signaling pathway|upregulation of intracellular signal transduction|activation of signal transmission via intracellular cascade|up regulation of signal transduction via intracellular signaling cascade|up-regulation of intracellular signaling chain|positive regulation of intracellular protein kinase cascade|activation of signal transduction via intracellular signaling cascade|positive regulation of intracellular signal transduction pathway						bf	2013-12-02T11:33:10Z			GO:0010740			biological_process											owl:Class	
GO:0010293	biolink:NamedThing	abscisic aldehyde oxidase activity	Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+).	got7fsn_ti	AAO3|abscisic-aldehyde oxidase activity|AOdelta|abscisic-aldehyde:oxygen oxidoreductase activity										GO:0033725	EC:1.2.3.14|KEGG_REACTION:R06957|MetaCyc:1.2.3.14-RXN|RHEA:20529		molecular_function											owl:Class	
GO:0102864	biolink:NamedThing	1-18:3-2-18:2-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:3-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8331		molecular_function											owl:Class	
GO:0004473	biolink:NamedThing	malate dehydrogenase (decarboxylating) (NADP+) activity	Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.	got7fsn_ti	NADP-specific malic enzyme|NADP-malic enzyme activity|L-malate:NADP oxidoreductase activity|NADP-linked decarboxylating malic enzyme|malate dehydrogenase (decarboxylating, NADP)|NADP-specific malate dehydrogenase activity|'malic' enzyme|(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|malate dehydrogenase (NADP, decarboxylating)				For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.40), see 'oxaloacetate decarboxylase activity ; GO:0008948'.							Reactome:R-HSA-9012036|KEGG_REACTION:R00216|Reactome:R-HSA-9012349|MetaCyc:MALIC-NADP-RXN|EC:1.1.1.40|RHEA:18253		molecular_function											owl:Class	
GO:0102102	biolink:NamedThing	homocarnosine synthase activity	Catalysis of the reaction: gamma-aminobutyric acid  + L-histidine  + ATP = H+ + homocarnosine + ADP + hydrogenphosphate.	got7fsn_ti												RHEA:59568|EC:6.3.2.11|MetaCyc:RXN-11222		molecular_function											owl:Class	
GO:0050686	biolink:NamedThing	negative regulation of mRNA processing	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.	got7fsn_ti	down-regulation of mRNA processing|downregulation of mRNA processing|inhibition of mRNA processing|down regulation of mRNA processing													biological_process											owl:Class	
GO:1990338	biolink:NamedThing	laminin-14 complex	A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains.	got7fsn_ti	laminin-423						bhm	2014-03-20T23:37:11Z						cellular_component											owl:Class	
GO:0002937	biolink:NamedThing	tRNA 4-thiouridine biosynthesis	The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.	got7fsn_ti					In E. coli, two genes are involved, nuvA (aka Thi) and NuvC (aka iscS) . NuvA converts the trNA into an unidentified intermediate in an ATP dependent manner. NucC catalyzes the second step, transferring the sulfur from cysteine to an unidentified intermediate. NuvC also participates in thiamine synthesis.		hjd	2012-10-19T15:26:28Z						biological_process											owl:Class	
GO:0140057	biolink:NamedThing	vacuole-mitochondria membrane tethering	The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.	got7fsn_ti							pg	2017-06-27T10:31:12Z						biological_process											owl:Class	
GO:1990024	biolink:NamedThing	C bouton	Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons.	got7fsn_ti							pr	2013-02-06T10:27:41Z				NIF_Subcellular:nlx_subcell_100208		cellular_component											owl:Class	
GO:0047313	biolink:NamedThing	aromatic-amino-acid-glyoxylate transaminase activity	Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid.	got7fsn_ti	aromatic-amino-acid:glyoxylate aminotransferase activity|aromatic-amino-acid-glyoxylate aminotransferase activity|aromatic-amino-acid--glyoxylate aminotransferase activity											EC:2.6.1.60|MetaCyc:2.6.1.60-RXN|RHEA:10900		molecular_function											owl:Class	
GO:1901607	biolink:NamedThing	alpha-amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of an alpha-amino acid.	got7fsn_ti	alpha-amino acid synthesis|alpha-amino acid formation|alpha-amino acid anabolism|alpha-amino acid biosynthesis						tb	2012-11-08T17:39:58Z						biological_process											owl:Class	
GO:0071455	biolink:NamedThing	cellular response to hyperoxia	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.	got7fsn_ti	cellular response to hyperoxic stress|cellular response to increased oxygen tension						mah	2009-12-16T04:44:41Z						biological_process											owl:Class	
GO:0009882	biolink:NamedThing	blue light photoreceptor activity	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.	got7fsn_ti														molecular_function											owl:Class	
GO:0036158	biolink:NamedThing	outer dynein arm assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.	got7fsn_ti	ODA assembly						bf	2012-03-21T02:25:01Z						biological_process											owl:Class	
GO:0015042	biolink:NamedThing	trypanothione-disulfide reductase activity	Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.	got7fsn_ti	trypanothione-disulphide reductase activity|trypanothione:NADP+ oxidoreductase activity|NADPH:trypanothione oxidoreductase activity|N1,N8-bis(glutathionyl)spermidine reductase activity|trypanothione reductase activity|N(1),N(8)-bis(glutathionyl)spermidine reductase activity				Note that this function was formerly EC:1.6.4.8.							MetaCyc:1.8.1.12-RXN|EC:1.8.1.12|RHEA:16757		molecular_function											owl:Class	
GO:0005157	biolink:NamedThing	macrophage colony-stimulating factor receptor binding	Binding to a macrophage colony-stimulating factor receptor.	got7fsn_ti	macrophage colony-stimulating factor receptor ligand|M-CSF receptor binding|macrophage colony stimulating factor receptor binding													molecular_function											owl:Class	
GO:0061140	biolink:NamedThing	lung secretory cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.	got7fsn_ti							dph	2010-05-25T09:28:53Z						biological_process											owl:Class	
GO:0097243	biolink:NamedThing	flavonoid binding	Binding to a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge.	got7fsn_ti							pr	2012-02-17T03:49:16Z						molecular_function											owl:Class	
GO:0004732	biolink:NamedThing	pyridoxal oxidase activity	Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide.	got7fsn_ti	pyridoxal:oxygen 4-oxidoreductase activity											EC:1.2.3.8|RHEA:23724|MetaCyc:PYRIDOXAL-OXIDASE-RXN		molecular_function											owl:Class	
GO:0046213	biolink:NamedThing	methyl ethyl ketone catabolic process	The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor.	got7fsn_ti	methyl ethyl ketone catabolism|methyl ethyl ketone breakdown|methyl ethyl ketone degradation													biological_process											owl:Class	
GO:0071460	biolink:NamedThing	cellular response to cell-matrix adhesion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.	got7fsn_ti							mah	2009-12-17T02:25:45Z						biological_process											owl:Class	
GO:0019561	biolink:NamedThing	anaerobic phenylalanine oxidation	The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde.	got7fsn_ti												MetaCyc:ANAPHENOXI-PWY		biological_process											owl:Class	
GO:0006559	biolink:NamedThing	L-phenylalanine catabolic process	The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.	got7fsn_ti	phenylalanine catabolism|L-phenylalanine breakdown|phenylalanine catabolic process|L-phenylalanine degradation|L-phenylalanine catabolism													biological_process											owl:Class	
GO:0047090	biolink:NamedThing	benzoyl-CoA 3-monooxygenase activity	Catalysis of the reaction: benzoyl-CoA + H(+) + NADPH + O(2) = 3-hydroxybenzoyl-CoA + H(2)O + NADP(+).	got7fsn_ti	benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)|benzoyl-CoA 3-hydroxylase activity											KEGG_REACTION:R02449|RHEA:23216|EC:1.14.13.58|MetaCyc:1.14.13.58-RXN		molecular_function											owl:Class	
GO:0032943	biolink:NamedThing	mononuclear cell proliferation	The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.	got7fsn_ti	PBMC proliferation|peripheral blood mononuclear cell proliferation													biological_process											owl:Class	
GO:0032389	biolink:NamedThing	MutLalpha complex	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.	got7fsn_ti	MLH1/PMS2 complex|MMR complex|MutL-alpha complex													cellular_component											owl:Class	
GO:0048905	biolink:NamedThing	anterior lateral line neuromast mantle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.	got7fsn_ti														biological_process											owl:Class	
GO:0102930	biolink:NamedThing	4-hydroxybenzoate geranyltransferase activity	Catalysis of the reaction: geranyl diphosphate + 4-hydroxybenzoic acid = 3-geranyl-4-hydroxybenzoate + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8920|EC:2.5.1.93|RHEA:27854		molecular_function											owl:Class	
GO:0032089	biolink:NamedThing	NACHT domain binding	Binding to a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs.	got7fsn_ti														molecular_function											owl:Class	
GO:0035918	biolink:NamedThing	negative regulation of voltage-gated calcium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	down-regulation of voltage-gated calcium channel activity in other organism|downregulation of voltage-gated calcium channel activity in other organism|negative regulation of voltage-sensitive calcium channel activity in other organism|inhibition of voltage-gated calcium channel activity in other organism|negative regulation of voltage gated calcium channel activity in other organism|negative regulation of voltage-dependent calcium channel activity in other organism						bf	2011-07-01T11:54:43Z						biological_process											owl:Class	
GO:0030423	biolink:NamedThing	targeting of mRNA for destruction involved in RNA interference	The process in which small interfering RNAs target cognate mRNA molecules for degradation.	got7fsn_ti	RNA interference, targeting of mRNA for destruction													biological_process											owl:Class	
GO:0038149	biolink:NamedThing	C-C motif chemokine 2 receptor activity	Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	CCL2 receptor activity						bf	2012-05-11T11:37:16Z						molecular_function											owl:Class	
GO:0060963	biolink:NamedThing	positive regulation of ribosomal protein gene transcription by RNA polymerase II	Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.	got7fsn_ti	positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter						dph	2009-10-05T03:04:05Z						biological_process											owl:Class	
GO:0007481	biolink:NamedThing	haltere disc morphogenesis	The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.	got7fsn_ti	haltere disc metamorphosis													biological_process											owl:Class	
GO:1990511	biolink:NamedThing	piRNA biosynthetic process	The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	got7fsn_ti	Piwi-associated RNA biosynthetic process						kmv	2014-10-07T13:47:32Z						biological_process											owl:Class	
GO:0007384	biolink:NamedThing	specification of segmental identity, thorax	The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0035292	biolink:NamedThing	specification of segmental identity, trunk	The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0031756	biolink:NamedThing	Edg-3 sphingosine 1-phosphate receptor binding	Binding to an Edg-3 sphingosine 1-phosphate receptor.	got7fsn_ti	Edg-3 sphingosine 1-phosphate receptor ligand													molecular_function											owl:Class	
GO:0106377	biolink:NamedThing	2-hydroxy-ATP hydrolase activity	Catalysis of the reaction: 2-hydroxy-ATP + H2O = 2-hydroxy-AMP + diphosphate.	got7fsn_ti							hjd	2021-04-23T00:12:31Z						molecular_function											owl:Class	
GO:0004800	biolink:NamedThing	thyroxine 5'-deiodinase activity	Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.	got7fsn_ti	iodothyronine 5'-deiodinase activity|thyroxine 5' deiodinase activity|diiodothyronine 5'-deiodinase activity|outer ring-deiodinating pathway|type I iodothyronine deiodinase activity|thyroxine deiodinase activity|acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)|iodothyronine outer ring monodeiodinase activity|L-thyroxine iodohydrolase (reducing) activity|type II iodothyronine deiodinase activity				Note that this was EC:3.8.1.4.							MetaCyc:THYROXINE-DEIODINASE-RXN|Reactome:R-HSA-350869|RHEA:19745|Reactome:R-HSA-209772|EC:1.21.99.4		molecular_function											owl:Class	
GO:0035384	biolink:NamedThing	thioester biosynthetic process	The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.	got7fsn_ti	thioester formation|thioester anabolism|thioester synthesis|thioester biosynthesis						bf	2010-03-18T01:52:11Z						biological_process											owl:Class	
GO:0030148	biolink:NamedThing	sphingolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	got7fsn_ti	sphingolipid synthesis|sphingolipid formation|sphingolipid biosynthesis|sphingolipid anabolism											MetaCyc:PWY-5129		biological_process											owl:Class	
GO:0035281	biolink:NamedThing	pre-miRNA export from nucleus	Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product.	got7fsn_ti	pre-microRNA transport from nucleus to cytoplasm|pre-microRNA export from nucleus|pre-microRNA export from cell nucleus|pre-microRNA-nucleus export|pre-microRNA export out of nucleus													biological_process											owl:Class	
GO:0006405	biolink:NamedThing	RNA export from nucleus	The directed movement of RNA from the nucleus to the cytoplasm.	got7fsn_ti	RNA transport from nucleus to cytoplasm|RNA export out of nucleus|RNA export from cell nucleus|RNA-nucleus export													biological_process											owl:Class	
GO:0018866	biolink:NamedThing	adamantanone metabolic process	The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.	got7fsn_ti	adamantanone metabolism											UM-BBD_pathwayID:ada		biological_process											owl:Class	
GO:0102857	biolink:NamedThing	1-18:1-2-18:3-phosphatidylcholinedesaturase activity	Catalysis of the reaction: 1-18:1-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8324|EC:1.14.19.22		molecular_function											owl:Class	
GO:0007554	biolink:NamedThing	regulation of ecdysteroid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.	got7fsn_ti	regulation of ecdysteroid anabolism|regulation of ecdysteroid biosynthesis|regulation of ecdysteroid formation|regulation of ecdysteroid synthesis													biological_process											owl:Class	
GO:0047097	biolink:NamedThing	phylloquinone monooxygenase (2,3-epoxidizing) activity	Catalysis of the reaction: AH(2) + O(2) + phylloquinone = 2,3-epoxyphylloquinone + A + H(2)O.	got7fsn_ti	vitamin K 2,3-epoxidase activity|phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)|vitamin K epoxidase activity|phylloquinone epoxidase activity|vitamin K1 epoxidase activity											EC:1.14.99.20|MetaCyc:1.14.99.20-RXN|KEGG_REACTION:R03510|RHEA:16745		molecular_function											owl:Class	
GO:0070679	biolink:NamedThing	inositol 1,4,5 trisphosphate binding	Binding to inositol 1,4,5 trisphosphate.	got7fsn_ti	InsP3 binding|IP3 binding						mah	2009-05-29T04:07:00Z						molecular_function											owl:Class	
GO:0033661	biolink:NamedThing	effector-mediated defense to host-produced reactive oxygen species	A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	down regulation by organism of defense-related host metabolic burst|negative regulation by organism of defense-related host ROS production|suppression by symbiont of defense-related host reactive oxygen species production|down-regulation by organism of defense-related host oxidative burst|negative regulation by organism of defense-related host ROI production|negative regulation by organism of defense-related host reactive oxidative species production|inhibition by organism of defense-related host active oxygen species production|negative regulation by organism of defense-related host reactive oxygen intermediate production|negative regulation by organism of defense-related host respiratory burst|negative regulation by symbiont of defense-related host reactive oxygen species production|downregulation by organism of defense-related host AOS production	https://github.com/geneontology/go-ontology/issues/18697												biological_process											owl:Class	
GO:0120149	biolink:NamedThing	host cell peroxisome	A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.	got7fsn_ti	host peroxisome						krc	2018-04-13T15:36:40Z						cellular_component											owl:Class	
GO:0017051	biolink:NamedThing	retinol dehydratase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol.	got7fsn_ti														molecular_function											owl:Class	
GO:0010938	biolink:NamedThing	cytoplasmic microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.	got7fsn_ti														biological_process											owl:Class	
GO:0031122	biolink:NamedThing	cytoplasmic microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.	got7fsn_ti	cytoplasmic microtubule organization and biogenesis|cytoplasmic microtubule organisation													biological_process											owl:Class	
GO:0072438	biolink:NamedThing	response to DNA replication checkpoint signaling	A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling.	got7fsn_ti	response to signal involved in DNA replication checkpoint|DNA replication checkpoint effector process						mah	2010-12-08T04:53:12Z						biological_process											owl:Class	
GO:0018411	biolink:NamedThing	protein glucuronidation	The modification of a protein by amino acid glucuronidation.	got7fsn_ti	protein amino acid glucuronidation													biological_process											owl:Class	
GO:0045721	biolink:NamedThing	negative regulation of gluconeogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.	got7fsn_ti	down-regulation of gluconeogenesis|down regulation of gluconeogenesis|downregulation of gluconeogenesis|inhibition of gluconeogenesis													biological_process											owl:Class	
GO:0004854	biolink:NamedThing	xanthine dehydrogenase activity	Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+.	got7fsn_ti	xanthine-NAD oxidoreductase activity|xanthine:NAD+ oxidoreductase activity|xanthine/NAD(+) oxidoreductase activity|NAD-xanthine dehydrogenase activity|xanthine/NAD+ oxidoreductase activity|xanthine oxidoreductase activity											RHEA:16669|MetaCyc:RXN0-901|EC:1.17.1.4		molecular_function											owl:Class	
GO:0042062	biolink:NamedThing	long-term strengthening of neuromuscular junction	Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.	got7fsn_ti														biological_process											owl:Class	
GO:0050806	biolink:NamedThing	positive regulation of synaptic transmission	Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.	got7fsn_ti	upregulation of synaptic transmission|up-regulation of synaptic transmission|stimulation of synaptic transmission|up regulation of synaptic transmission|activation of synaptic transmission													biological_process											owl:Class	
GO:0070359	biolink:NamedThing	actin polymerization-dependent cell motility involved in migration of symbiont in host	A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell.	got7fsn_ti	actin polymerization-dependent cell motility involved in migration of symbiont within host													biological_process											owl:Class	
GO:0035062	biolink:NamedThing	omega speckle	A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).	got7fsn_ti														cellular_component											owl:Class	
GO:0042723	biolink:NamedThing	thiamine-containing compound metabolic process	The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.	got7fsn_ti	thiamine and derivative metabolism|thiamine-containing compound metabolism|thiamine and derivative metabolic process|thiamin-containing compound metabolic process|thiamin and derivative metabolic process|thiamin and derivative metabolism|vitamin B1 and derivative metabolism|vitamin B1 and derivative metabolic process													biological_process											owl:Class	
GO:0042356	biolink:NamedThing	GDP-4-dehydro-D-rhamnose reductase activity	Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.	got7fsn_ti	GDP-4-keto-D-rhamnose reductase activity|GDP-4-keto-6-deoxy-D-mannose reductase activity|GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity|guanosine diphosphate-4-keto-D-rhamnose reductase activity											EC:1.1.1.187|MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0018661	biolink:NamedThing	orcinol 2-monooxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + orcinol = 2,3,5-trihydroxytoluene + H(2)O + NAD(+).	got7fsn_ti	orcinol hydroxylase activity|orcinol,NADH:oxygen oxidoreductase (2-hydroxylating)											KEGG_REACTION:R02830|MetaCyc:ORCINOL-2-MONOOXYGENASE-RXN|EC:1.14.13.6|RHEA:19601|UM-BBD_reactionID:r0092		molecular_function											owl:Class	
GO:0052836	biolink:NamedThing	inositol 5-diphosphate pentakisphosphate 5-kinase activity	Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate.	got7fsn_ti							ai	2011-11-29T01:14:22Z				Reactome:R-HSA-1855224|Reactome:R-HSA-1855158		molecular_function											owl:Class	
GO:1990055	biolink:NamedThing	phenylacetaldehyde synthase activity	Catalyzes the reaction: L-phenylalanine + O2 + H2O -> phenylacetaldehyde + ammonia + hydrogen peroxide + CO2.	got7fsn_ti	aromatic aldehyde synthase						tb	2013-02-25T20:22:35Z				EC:4.1.1.109|RHEA:55532		molecular_function											owl:Class	
GO:0022417	biolink:NamedThing	protein maturation by protein folding	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0050314	biolink:NamedThing	sym-norspermidine synthase activity	Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H(+).	got7fsn_ti	S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase activity											RHEA:23244|MetaCyc:SYM-NORSPERMIDINE-SYNTHASE-RXN|KEGG_REACTION:R03271|EC:2.5.1.23		molecular_function											owl:Class	
GO:0050333	biolink:NamedThing	thiamin-triphosphatase activity	Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate.	got7fsn_ti	ThTPase activity|thiamine-triphosphatase activity|thiamine-triphosphate phosphohydrolase activity										GO:0048253	EC:3.6.1.28|KEGG_REACTION:R00618|Reactome:R-HSA-965067|MetaCyc:THIAMIN-TRIPHOSPHATASE-RXN|RHEA:11744		molecular_function											owl:Class	
GO:0044149	biolink:NamedThing	positive regulation of formation of structure involved in a symbiotic process	Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	got7fsn_ti	positive regulation of development of symbiont involved in interaction with host|positive regulation of development of symbiont during interaction with host	https://github.com/geneontology/go-ontology/issues/20305			This term partially replaces the obsolete term 'positive regulation of growth or development of symbiont during interaction with host ; GO:0075339'. See also 'positive regulation of growth of symbiont during interaction with host ; GO:0044148'.		jl	2009-08-06T02:20:55Z						biological_process											owl:Class	
GO:0097488	biolink:NamedThing	multivesicular body, internal vesicle membrane	The lipid bilayer surrounding a multivesicular body internal vesicle.	got7fsn_ti							pr	2013-07-08T20:36:33Z						cellular_component											owl:Class	
GO:0048572	biolink:NamedThing	short-day photoperiodism	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length.	got7fsn_ti	long-night photoperiodism|response to long-night|response to short-day|response to short-day photoperiod													biological_process											owl:Class	
GO:0032988	biolink:NamedThing	ribonucleoprotein complex disassembly	The disaggregation of a protein-RNA complex into its constituent components.	got7fsn_ti	RNA-protein complex disassembly|protein-RNA complex disassembly|RNP complex disassembly													biological_process											owl:Class	
GO:0071826	biolink:NamedThing	ribonucleoprotein complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.	got7fsn_ti	ribonucleoprotein complex subunit organisation|RNA-protein complex subunit organization|protein-RNA complex subunit organization						mah	2010-09-08T10:10:35Z						biological_process											owl:Class	
GO:0098996	biolink:NamedThing	disruption of host cell glycocalyx during viral entry	The disruption of host cell glycocalyx by viral proteins during virus entry.	got7fsn_ti	degradation of host capsule during virus entry|catabolism of host glycocalyx during viral entry|degradation of host glycocalyx during viral entry|disassembly of glycocalyx during viral entry											VZ:3938		biological_process											owl:Class	
GO:0033459	biolink:NamedThing	GAA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GAA codon.	got7fsn_ti	glutamic acid tRNA				Note that in the standard genetic code, GAA codes for glutamic acid.									molecular_function											owl:Class	
GO:0072143	biolink:NamedThing	mesangial cell development	The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.	got7fsn_ti							mah	2010-02-24T01:44:28Z						biological_process											owl:Class	
GO:0102791	biolink:NamedThing	sulfuretin synthase activity	Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 + 2 H+ = sulfuretin 6-glucoside + 2 H2O.	got7fsn_ti												MetaCyc:RXN-8008|EC:1.21.3.6		molecular_function											owl:Class	
GO:0050275	biolink:NamedThing	scopoletin glucosyltransferase activity	Catalysis of the reaction: scopoletin + UDP-D-glucose = H(+) + scopolin + UDP.	got7fsn_ti	UDPglucose:scopoletin O-beta-D-glucosyltransferase activity|SGTase activity|UDP-glucose:scopoletin O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-scopoletin glucosyltransferase activity|UDPglucose:scopoletin glucosyltransferase activity											RHEA:20453|MetaCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.128|KEGG_REACTION:R03594		molecular_function											owl:Class	
GO:0072494	biolink:NamedThing	host multivesicular body	A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.	got7fsn_ti	host cell multivesicular body						mah	2010-12-15T11:48:39Z						cellular_component											owl:Class	
GO:0010210	biolink:NamedThing	IAA-Phe conjugate hydrolase activity	Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine.	got7fsn_ti														molecular_function											owl:Class	
GO:0046421	biolink:NamedThing	methylisocitrate lyase activity	Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.	got7fsn_ti	(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase activity|2-methylisocitrate lyase activity|MICL|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming)											RHEA:16809|EC:4.1.3.30|MetaCyc:METHYLISOCITRATE-LYASE-RXN|KEGG_REACTION:R00409		molecular_function											owl:Class	
GO:0021532	biolink:NamedThing	neural tube patterning	The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.	got7fsn_ti														biological_process											owl:Class	
GO:0070048	biolink:NamedThing	endobrevin-SNAP-25-syntaxin-1a complex	A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof).	got7fsn_ti	SNARE complex (Stx1a, Snap25, Vamp8)|Stx1a-Snap25-Vamp8 complex													cellular_component											owl:Class	
GO:0039530	biolink:NamedThing	MDA-5 signaling pathway	Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. MDA-5 detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	got7fsn_ti	MDA5 signaling pathway|IFIH1 signaling pathway|MDA-5 signalling pathway|melanoma differentiation-associated gene 5 signaling pathway						bf	2011-12-20T03:14:52Z						biological_process											owl:Class	
GO:0044398	biolink:NamedThing	envenomation resulting in induction of edema in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation.	got7fsn_ti	envenomation resulting in induction of oedema in other organism						jl	2011-12-21T03:57:27Z						biological_process											owl:Class	
GO:0031340	biolink:NamedThing	positive regulation of vesicle fusion	Any process that activates or increases the frequency, rate or extent of vesicle fusion.	got7fsn_ti	up-regulation of vesicle fusion|up regulation of vesicle fusion|stimulation of vesicle fusion|upregulation of vesicle fusion|activation of vesicle fusion													biological_process											owl:Class	
GO:0060876	biolink:NamedThing	semicircular canal formation	The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.	got7fsn_ti							dph	2009-08-13T09:45:07Z						biological_process											owl:Class	
GO:0080105	biolink:NamedThing	6-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate.	got7fsn_ti							dhl	2009-04-23T04:28:55Z						molecular_function											owl:Class	
GO:0034466	biolink:NamedThing	chromaffin granule lumen	The volume enclosed by the membrane of a chromaffin granule.	got7fsn_ti														cellular_component											owl:Class	
GO:0036423	biolink:NamedThing	hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate.	got7fsn_ti	hexaprenyl diphosphate synthase activity|hexaprenyl pyrophosphate synthetase activity						bf	2013-09-16T12:22:10Z				KEGG_REACTION:R09245|EC:2.5.1.83|RHEA:27559|MetaCyc:TRANS-PENTAPRENYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0050796	biolink:NamedThing	regulation of insulin secretion	Any process that modulates the frequency, rate or extent of the regulated release of insulin.	got7fsn_ti														biological_process											owl:Class	
GO:0097390	biolink:NamedThing	chemokine (C-X-C motif) ligand 12 production	The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CXCL12 production						pr	2012-10-23T07:57:28Z						biological_process											owl:Class	
GO:0047022	biolink:NamedThing	7-beta-hydroxysteroid dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.	got7fsn_ti	NADP-dependent 7beta-hydroxysteroid dehydrogenase activity|7beta-hydroxysteroid dehydrogenase (NADP+)|NADP-dependent 7-beta-hydroxysteroid dehydrogenase activity|7beta-hydroxysteroid:NADP+ 7-oxidoreductase activity											Wikipedia:7beta-hydroxysteroid_dehydrogenase_(NADP+)|EC:1.1.1.201|MetaCyc:1.1.1.201-RXN|RHEA:20233		molecular_function											owl:Class	
GO:0018783	biolink:NamedThing	deisopropyldeethylatrazine hydrolase activity	Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3.	got7fsn_ti														molecular_function											owl:Class	
GO:0102265	biolink:NamedThing	tRNA-dihydrouridine47 synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil47 in tRNA + NAD(P) <=> H+ + a uracil47 in tRNA + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-12457|EC:1.3.1.89		molecular_function											owl:Class	
GO:0043479	biolink:NamedThing	pigment accumulation in tissues in response to UV light	The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0070995	biolink:NamedThing	NADPH oxidation	A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.	got7fsn_ti	NADPH dehydrogenation|reduced NADP oxidation|reduced nicotinamide adenine dinucleotide phosphate oxidation|NADP (reduced) dehydrogenation|reduced nicotinamide adenine dinucleotide phosphate dehydrogenation|NADP (reduced) oxidation|reduced NADP dehydrogenation						mah	2009-11-03T12:02:15Z						biological_process											owl:Class	
GO:0000380	biolink:NamedThing	alternative mRNA splicing, via spliceosome	The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.	got7fsn_ti	alternative nuclear mRNA splicing, via spliceosome|splice site selection				Note that this process most commonly occurs in cis, selecting or skipping exons from the same primary transcript, but it has also been observed to occur in trans at low frequency, at least in some mammals.									biological_process											owl:Class	
GO:0032037	biolink:NamedThing	myosin I heavy chain binding	Binding to a heavy chain of a myosin I complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0080100	biolink:NamedThing	L-glutamine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate.	got7fsn_ti	L-glutamine:alpha-ketoglutarate aminotransferase activity				This reaction falls within the larger set of reactions associated with EC:2.6.1.50 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.50).		dhl	2009-04-23T03:56:16Z				EC:2.6.1.50		molecular_function											owl:Class	
GO:0090512	biolink:NamedThing	eisosome membrane domain/MCC	A plasma membrane part that is composed of a furrow-like plasma membrane domain and associated integral transmembrane proteins.	got7fsn_ti							tb	2012-12-07T17:00:19Z						cellular_component											owl:Class	
GO:0047327	biolink:NamedThing	glycerol-3-phosphate-glucose phosphotransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol.	got7fsn_ti	sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase activity											EC:2.7.1.142|MetaCyc:2.7.1.142-RXN|RHEA:21288|KEGG_REACTION:R00850		molecular_function											owl:Class	
GO:0110100	biolink:NamedThing	spindle pole body separation	The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		kmv	2018-03-06T15:09:28Z						biological_process											owl:Class	
GO:0070140	biolink:NamedThing	SUMO-specific isopeptidase activity	Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated.	got7fsn_ti														molecular_function											owl:Class	
GO:0047907	biolink:NamedThing	furylfuramide isomerase activity	Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.	got7fsn_ti	2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase activity											RHEA:21848|KEGG_REACTION:R04538|EC:5.2.1.6|MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN		molecular_function											owl:Class	
GO:0005497	biolink:NamedThing	androgen binding	Binding to an androgen, a male sex hormone.	got7fsn_ti														molecular_function											owl:Class	
GO:0106286	biolink:NamedThing	(E)-caffeate-CoA ligase activity	Catalysis of the reaction: (E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate.	got7fsn_ti							hjd	2020-07-30T14:26:08Z				RHEA:36299		molecular_function											owl:Class	
GO:0018172	biolink:NamedThing	peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine	The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine.	got7fsn_ti	peptidyl-L-3',4',5'-trihydroxyphenylalanine formation from peptidyl-tyrosine|peptidyl-L-3',4',5'-trihydroxyphenylalanine anabolism from peptidyl-tyrosine|peptidyl-L-3',4',5'-trihydroxyphenylalanine synthesis from peptidyl-tyrosine											RESID:AA0263		biological_process											owl:Class	
GO:0018336	biolink:NamedThing	peptidyl-tyrosine hydroxylation	The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine.	got7fsn_ti														biological_process											owl:Class	
GO:0031700	biolink:NamedThing	adrenomedullin receptor binding	Binding to an adrenomedullin receptor.	got7fsn_ti	adrenomedullin receptor ligand													molecular_function											owl:Class	
GO:0102666	biolink:NamedThing	indole-3-acetyl-beta-4-D-glucose hydrolase activity	Catalysis of the reaction: indole-3-acetyl-beta-4-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-3164		molecular_function											owl:Class	
GO:0050416	biolink:NamedThing	formimidoylglutamate deiminase activity	Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3.	got7fsn_ti	formiminoglutamic iminohydrolase activity|formiminoglutamate deiminase activity|N-formimidoyl-L-glutamate iminohydrolase activity											RHEA:22832|EC:3.5.3.13|MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN		molecular_function											owl:Class	
GO:0120170	biolink:NamedThing	intraciliary transport particle B binding	Binding to an intraciliary transport particle B (IFT B) complex.	got7fsn_ti	IFT B complex binding|intraflagellar transport complex B binding|intraciliary transport complex B binding|intraflagellar transport particle B binding						krc	2018-05-11T22:28:11Z						molecular_function											owl:Class	
GO:0035361	biolink:NamedThing	Cul8-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins.	got7fsn_ti							bf	2010-03-05T02:41:12Z						cellular_component											owl:Class	
GO:0060422	biolink:NamedThing	peptidyl-dipeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain.	got7fsn_ti												Wikipedia:ACE_inhibitor		molecular_function											owl:Class	
GO:0030414	biolink:NamedThing	peptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.	got7fsn_ti	protease inhibitor activity													molecular_function											owl:Class	
GO:0019506	biolink:NamedThing	phenylmercury acetate catabolic process	The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.	got7fsn_ti	phenylmercury acetate breakdown|phenylmercury acetate catabolism|phenylmercury acetate degradation											MetaCyc:P641-PWY		biological_process											owl:Class	
GO:0005223	biolink:NamedThing	intracellular cGMP-activated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	intracellular cGMP activated cation channel activity													molecular_function											owl:Class	
GO:0046548	biolink:NamedThing	retinal rod cell development	Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.	got7fsn_ti														biological_process											owl:Class	
GO:0042462	biolink:NamedThing	eye photoreceptor cell development	Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0001852	biolink:NamedThing	complement component iC3b binding	Binding to a iC3b product of the complement cascade.	got7fsn_ti														molecular_function											owl:Class	
GO:0051575	biolink:NamedThing	5'-deoxyribose-5-phosphate lyase activity	Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site.	got7fsn_ti	dRPase activity|dRP lyase activity|5'-deoxyribose phosphate activity													molecular_function											owl:Class	
GO:0039560	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity	Any process in which a virus stops, prevents, or reduces a JAK1-STAT signaling cascade in a host organism by reducing the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes.	got7fsn_ti	inhibition of host IRF9 by virus|suppression by virus of host IRF9 activity|inhibition of host interferon regulatory factor-9 by virus|suppression by virus of host interferon regulatory factor 9 activity	https://github.com/geneontology/go-ontology/issues/21986			This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-03-09T04:42:08Z						biological_process											owl:Class	
GO:0097388	biolink:NamedThing	chemokine (C-C motif) ligand 19 production	The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	MIP-3-beta production|CCL19 production|EBI1 ligand chemokine production|macrophage inflammatory protein-3-beta production|ELC production						pr	2012-10-23T07:54:10Z						biological_process											owl:Class	
GO:0035769	biolink:NamedThing	B cell chemotaxis across high endothelial venule	The movement of a B cell to cross a high endothelial venule in response to an external stimulus.	got7fsn_ti	B-cell chemotaxis across high endothelial venule						bf	2011-04-01T10:48:59Z						biological_process											owl:Class	
GO:0002518	biolink:NamedThing	lymphocyte chemotaxis across high endothelial venule	The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0047821	biolink:NamedThing	D-glutamate oxidase activity	Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2.	got7fsn_ti	D-glutamic acid oxidase activity|D-glutamate:oxygen oxidoreductase (deaminating)|D-glutamic oxidase activity											RHEA:10028|EC:1.4.3.7|KEGG_REACTION:R00279|MetaCyc:D-GLUTAMATE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0009395	biolink:NamedThing	phospholipid catabolic process	The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.	got7fsn_ti	phospholipid breakdown|phospholipid catabolism|phospholipid degradation													biological_process											owl:Class	
GO:0004049	biolink:NamedThing	anthranilate synthase activity	Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.	got7fsn_ti	chorismate pyruvate-lyase (amino-accepting) activity|anthranilate synthetase activity											EC:4.1.3.27|RHEA:21732|MetaCyc:ANTHRANSYN-RXN		molecular_function											owl:Class	
GO:0044636	biolink:NamedThing	envenomation resulting in modulation of complement activation, classical pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism.	got7fsn_ti							jl	2012-07-05T04:40:57Z						biological_process											owl:Class	
GO:0098758	biolink:NamedThing	response to interleukin-8	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.	got7fsn_ti	response to IL-8													biological_process											owl:Class	
GO:0102068	biolink:NamedThing	alpha-humulene 10-hydroxylase activity	Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 10-hydroxy-alpha-humulene + NADP + H2O.	got7fsn_ti												EC:1.14.14.113|MetaCyc:RXN-10628|RHEA:32491		molecular_function											owl:Class	
GO:0070644	biolink:NamedThing	vitamin D response element binding	Binding to a vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.	got7fsn_ti	VDRE binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		mah	2009-05-08T04:23:44Z						molecular_function											owl:Class	
GO:0102070	biolink:NamedThing	18-hydroxyoleate peroxygenase activity	Catalysis of the reaction: 18-hydroxyoleate + a lipid hydroperoxide <=> 9,10-epoxy-18-hydroxystearate + a lipid alcohol.	got7fsn_ti												MetaCyc:RXN-1064|EC:1.11.2.3		molecular_function											owl:Class	
GO:1901656	biolink:NamedThing	glycoside transport	The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							pr	2012-11-20T11:59:16Z						biological_process											owl:Class	
GO:0052933	biolink:NamedThing	alcohol dehydrogenase (cytochrome c(L)) activity	Catalysis of the reaction: 2 [Fe(III)cytochrome cL] + a primary alcohol = 2 [Fe(II)cytochrome cL] + an aldehyde + 2 H+.	got7fsn_ti	2-chloroethanol cytochrome-c oxidoreductase activity|methanol ferricytochrome-c oxidoreductase activity|ethanol cytochrome-c oxidoreductase activity|alcohol:cytochrome c(L) oxidoreductase activity|methanol dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/21412									GO:0052932|GO:0052930|GO:0052931	MetaCyc:RXN-11332|MetaCyc:RXN-2861|KEGG_REACTION:R01146|KEGG_REACTION:R09128|EC:1.1.2.7|RHEA:51004|KEGG_REACTION:R09127		molecular_function											owl:Class	
GO:0034564	biolink:NamedThing	4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity	Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0866		molecular_function											owl:Class	
GO:0050915	biolink:NamedThing	sensory perception of sour taste	The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti	sour taste perception													biological_process											owl:Class	
GO:0008910	biolink:NamedThing	kanamycin kinase activity	Catalysis of the reaction: ATP + kanamycin = ADP + 2 H(+) + kanamycin 3'-phosphate.	got7fsn_ti	neomycin-kanamycin phosphotransferase activity|APH(3') activity|kanamycin kinase (phosphorylating)|neomycin phosphotransferase activity|ATP:kanamycin 3'-O-phosphotransferase activity|aminoglycoside 3'-phosphotransferase activity											MetaCyc:KANAMYCIN-KINASE-RXN|KEGG_REACTION:R01888|EC:2.7.1.95|RHEA:24256		molecular_function											owl:Class	
GO:0001962	biolink:NamedThing	alpha-1,3-galactosyltransferase activity	Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.	got7fsn_ti	isoglobotriaosylceramide synthase													molecular_function											owl:Class	
GO:0048174	biolink:NamedThing	negative regulation of short-term neuronal synaptic plasticity	A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.	got7fsn_ti	down-regulation of short-term neuronal synaptic plasticity|down regulation of short-term neuronal synaptic plasticity|inhibition of short-term neuronal synaptic plasticity|downregulation of short-term neuronal synaptic plasticity				Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:0018288	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl tetrairon tetrasulphide											RESID:AA0140		biological_process											owl:Class	
GO:0018872	biolink:NamedThing	arsonoacetate metabolic process	The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides.	got7fsn_ti	arsonoacetate metabolism											UM-BBD_pathwayID:ara		biological_process											owl:Class	
GO:0010311	biolink:NamedThing	lateral root formation	The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.	got7fsn_ti	lateral root primordium development										GO:0010386			biological_process											owl:Class	
GO:0106328	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP.	got7fsn_ti							hjd	2020-09-30T13:46:37Z				EC:2.4.1.147|RHEA:46884		molecular_function											owl:Class	
GO:0005992	biolink:NamedThing	trehalose biosynthetic process	The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	got7fsn_ti	trehalose formation|trehalose biosynthesis|trehalose anabolism|mykose biosynthesis|trehalose synthesis|mycose biosynthetic process|mykose biosynthetic process|mycose biosynthesis											MetaCyc:TREHALOSESYN-PWY|MetaCyc:PWY-881|MetaCyc:TRESYN-PWY		biological_process											owl:Class	
GO:0004803	biolink:NamedThing	transposase activity	Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element.	got7fsn_ti	P-element encoded transposase activity										GO:0004804			molecular_function											owl:Class	
GO:1903983	biolink:NamedThing	positive regulation of microvillus length	A process that increases the length of a microvillus.	got7fsn_ti	up regulation of regulation of microvillus length|upregulation of regulation of microvillus length|up-regulation of regulation of microvillus length|activation of regulation of microvillus length						als	2015-03-03T13:23:58Z						biological_process											owl:Class	
GO:0032532	biolink:NamedThing	regulation of microvillus length	A process that modulates the length of a microvillus.	got7fsn_ti														biological_process											owl:Class	
GO:0017168	biolink:NamedThing	5-oxoprolinase (ATP-hydrolyzing) activity	Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate.	got7fsn_ti	oxoprolinase activity|pyroglutamic hydrolase activity|pyroglutamase (ATP-hydrolysing)|L-pyroglutamate hydrolase activity|5-oxo-L-prolinase activity|5-oxoprolinase activity|5-OPase activity|5-oxo-L-proline amidohydrolase (ATP-hydrolysing)|pyroglutamate hydrolase activity|pyroglutamase activity|pyroglutamase (ATP-hydrolyzing) activity|5-oxoprolinase (ATP-hydrolysing)											RHEA:10348|Wikipedia:5-oxoprolinase_(ATP-hydrolysing)|Reactome:R-HSA-5603208|Reactome:R-HSA-1247935|KEGG_REACTION:R00251|EC:3.5.2.9|MetaCyc:5-OXOPROLINASE-ATP-HYDROLYSING-RXN		molecular_function											owl:Class	
GO:0045095	biolink:NamedThing	keratin filament	A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins.	got7fsn_ti	basic/neutral keratin|acidic keratin													cellular_component											owl:Class	
GO:0005882	biolink:NamedThing	intermediate filament	A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.	got7fsn_ti	type II intermediate filament associated protein|intermediate filament associated protein|type I intermediate filament associated protein											NIF_Subcellular:sao952483289|Wikipedia:Intermediate_filament|FMA:63851		cellular_component											owl:Class	
GO:0097582	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p.	got7fsn_ti	Pmt1p-Pmt2p complex						pr	2014-03-02T18:13:34Z						cellular_component											owl:Class	
GO:0010598	biolink:NamedThing	NAD(P)H dehydrogenase complex (plastoquinone)	Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool.	got7fsn_ti														cellular_component											owl:Class	
GO:0007381	biolink:NamedThing	specification of segmental identity, labial segment	The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti					See also the fly_anatomy.ontology term 'labial segment ; FBbt:00000014'.									biological_process											owl:Class	
GO:0080193	biolink:NamedThing	diffuse secondary thickening	Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem.	got7fsn_ti					Occurs in the stems (PO:0009047) of some Arecaceae (palms).		dhl	2012-12-06T15:57:50Z						biological_process											owl:Class	
GO:0052899	biolink:NamedThing	N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	Catalysis of the reaction: H(2)O + N(1),N(12)-diacetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + N(1)-acetylspermidine.	got7fsn_ti	N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity											MetaCyc:RXN-10460|RHEA:25868|EC:1.5.3.13		molecular_function											owl:Class	
GO:0043490	biolink:NamedThing	malate-aspartate shuttle	The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.	got7fsn_ti	malate/aspartate shuttle|malate aspartate shuttle|malate:aspartate shuttle											Wikipedia:Malate-aspartate_shuttle		biological_process											owl:Class	
GO:1990542	biolink:NamedThing	mitochondrial transmembrane transport	The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion.	got7fsn_ti							vw	2014-11-19T11:19:21Z						biological_process											owl:Class	
GO:1901337	biolink:NamedThing	thioester transport	The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							bf	2012-09-03T13:14:44Z						biological_process											owl:Class	
GO:0102442	biolink:NamedThing	syringetin 3-O-methyltransferase activity	Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine  <=> 3,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13920		molecular_function											owl:Class	
GO:0039634	biolink:NamedThing	killing by virus of host cell during superinfection exclusion	The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus.	got7fsn_ti	killing by virus of host cells during superinfection exclusion|Rex exclusion|killing by virus of host cells involved in superinfection exclusion						bf	2012-08-10T14:46:03Z						biological_process											owl:Class	
GO:0098603	biolink:NamedThing	selenol Se-methyltransferase activity	Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine.	got7fsn_ti												Reactome:R-HSA-2408544		molecular_function											owl:Class	
GO:0043035	biolink:NamedThing	chromatin insulator sequence binding	Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.	got7fsn_ti														molecular_function											owl:Class	
GO:0043593	biolink:NamedThing	endospore coat	The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination.	got7fsn_ti														cellular_component											owl:Class	
GO:0035589	biolink:NamedThing	G protein-coupled purinergic nucleotide receptor signaling pathway	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.	got7fsn_ti	P2Y receptor signaling pathway|G-protein coupled purinergic nucleotide receptor signaling pathway|G-protein coupled purinergic nucleotide receptor signalling pathway						bf	2010-10-22T11:18:59Z						biological_process											owl:Class	
GO:0090520	biolink:NamedThing	sphingolipid mediated signaling pathway	A series of molecular signals mediated by a sphingolipid.	got7fsn_ti	ceramide signaling pathway|sphingolipid mediated signal transduction|sphingosine signaling pathway|ceramide 1-phosphate signaling pathway|sphingolipid signaling pathway|sphingolipid-mediated signaling pathway						tb	2013-01-08T09:30:54Z						biological_process											owl:Class	
GO:0043162	biolink:NamedThing	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.	got7fsn_ti	ubiquitin-dependent protein degradation via the multivesicular body pathway|ubiquitin-dependent protein catabolic process via the MVB pathway|ubiquitin-dependent protein catabolism via the MVB pathway|ubiquitin-dependent protein breakdown via the multivesicular body pathway													biological_process											owl:Class	
GO:0006511	biolink:NamedThing	ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.	got7fsn_ti	protein ubiquitination during ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolism|protein ubiquitylation during ubiquitin-dependent protein catabolism|ubiquitin-dependent proteolysis|protein ubiquitination during ubiquitin-dependent protein catabolism|myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process|protein degradation tagging activity|protein ubiquitination during ubiquitin-dependent protein breakdown|ubiquitin-dependent protein breakdown|protein ubiquitinylation during ubiquitin-dependent protein catabolic process|protein ubiquitination during ubiquitin-dependent protein degradation|protein ubiquitylation during ubiquitin-dependent protein catabolic process|protein ubiquitinylation during ubiquitin-dependent protein catabolism|myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown|ubiquitin-dependent protein degradation|myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation										GO:0043432|GO:0042787			biological_process											owl:Class	
GO:0120193	biolink:NamedThing	tight junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.	got7fsn_ti	occluding cell junction organization|occluding junction organization						krc	2018-08-14T23:05:40Z						biological_process											owl:Class	
GO:0045216	biolink:NamedThing	cell-cell junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.	got7fsn_ti	cell-cell junction organisation|cell-cell junction biogenesis|intercellular junction assembly and maintenance|cell-cell junction assembly and maintenance													biological_process											owl:Class	
GO:0001779	biolink:NamedThing	natural killer cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.	got7fsn_ti	NK cell differentiation|natural killer cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0052730	biolink:NamedThing	sarcosine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.	got7fsn_ti	SDMT|S-adenosyl-L-methionine:N,N-sarcosine N-methyltransferase activity						ai	2011-08-16T03:45:39Z				MetaCyc:RXN-9679|KEGG_REACTION:R07243|EC:2.1.1.156|EC:2.1.1.157|EC:2.1.1.162|MetaCyc:R481-RXN|MetaCyc:RXN-7042|RHEA:15453		molecular_function											owl:Class	
GO:0045552	biolink:NamedThing	dihydrokaempferol 4-reductase activity	Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+.	got7fsn_ti	dihydroflavonol 4-reductase activity|NADPH-dihydromyricetin reductase activity|dihydromyricetin reductase activity|dihydroflavanol 4-reductase activity|dihydroquercetin reductase activity|cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase activity											RHEA:23016|MetaCyc:DIHYDROKAEMPFEROL-4-REDUCTASE-RXN|EC:1.1.1.219		molecular_function											owl:Class	
GO:0044608	biolink:NamedThing	peptidyl-L-threonine methyl ester biosynthetic process from peptidyl-threonine	The modification of a C-terminal peptidyl-threonine to form peptidyl-L-threonine methyl ester.	got7fsn_ti	peptidyl-threonine esterification						jl	2012-05-30T02:47:57Z				RESID:AA0507		biological_process											owl:Class	
GO:0006481	biolink:NamedThing	C-terminal protein methylation	The methylation of the C-terminal amino acid of a protein.	got7fsn_ti	C-terminal protein amino acid methylation													biological_process											owl:Class	
GO:0030924	biolink:NamedThing	manganese incorporation into metallo-oxygen cluster	The incorporation of manganese into a metallo-oxygen cluster.	got7fsn_ti														biological_process											owl:Class	
GO:0030923	biolink:NamedThing	metal incorporation into metallo-oxygen cluster	The formation of a cluster of several metal atoms, including manganese or calcium, with one or more bridging (mu-bond) oxygen atoms; amino acids residues in proteins that may ligate the metal oxygen cluster are histidine, aspartate, and glutamate.	got7fsn_ti														biological_process											owl:Class	
GO:0061971	biolink:NamedThing	replacement bone morphogenesis	The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.	got7fsn_ti							dph	2018-02-12T18:10:59Z						biological_process											owl:Class	
GO:0052688	biolink:NamedThing	(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.	got7fsn_ti	3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity											KEGG_REACTION:R06515		molecular_function											owl:Class	
GO:0047588	biolink:NamedThing	5-aminopentanamidase activity	Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3.	got7fsn_ti	5-aminonorvaleramidase activity|5-aminopentanamide amidohydrolase activity|5-aminovaleramidase activity											MetaCyc:5-AMINOPENTANAMIDASE-RXN|RHEA:15677|EC:3.5.1.30		molecular_function											owl:Class	
GO:0004592	biolink:NamedThing	pantoate-beta-alanine ligase activity	Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.	got7fsn_ti	(R)-pantoate:beta-alanine ligase (AMP-forming)|D-pantoate:beta-alanine ligase (AMP-forming)|pantothenate synthetase activity|pantoate-activating enzyme activity|pantoic-activating enzyme activity											RHEA:10912|MetaCyc:PANTOATE-BETA-ALANINE-LIG-RXN|EC:6.3.2.1		molecular_function											owl:Class	
GO:0102296	biolink:NamedThing	4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity	Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+.	got7fsn_ti												RHEA:32035|MetaCyc:RXN-12718|EC:3.7.1.17		molecular_function											owl:Class	
GO:0010349	biolink:NamedThing	L-galactose dehydrogenase activity	Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+.	got7fsn_ti	L-galactose 1-dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/3975|https://github.com/geneontology/go-ontology/issues/21831										RHEA:31559|MetaCyc:RXN-1884|EC:1.1.1.316		molecular_function											owl:Class	
GO:0101027	biolink:NamedThing	optical nerve axon regeneration	The regrowth of axons of the optical nerve following their loss or damage.	got7fsn_ti														biological_process											owl:Class	
GO:0002752	biolink:NamedThing	cell surface pattern recognition receptor signaling pathway	Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.	got7fsn_ti	cell surface PRR signaling pathway|cell surface pathogen receptor signaling pathway|cell surface PAMP receptor signaling pathway|cell surface pattern recognition receptor signalling pathway	https://github.com/geneontology/go-ontology/issues/18588												biological_process											owl:Class	
GO:0102689	biolink:NamedThing	UDP-glucose:isopentenyladenine 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine <=> H+ + 7-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP.	got7fsn_ti												MetaCyc:RXN-4727		molecular_function											owl:Class	
GO:0032614	biolink:NamedThing	interleukin-11 production	The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-11 production|interleukin-11 biosynthetic process|interleukin-11 secretion										GO:0072609|GO:0042230			biological_process											owl:Class	
GO:0043244	biolink:NamedThing	regulation of protein-containing complex disassembly	Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.	got7fsn_ti	regulation of protein complex disassembly													biological_process											owl:Class	
GO:0022882	biolink:NamedThing	protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	beta-glucoside PTS transporter activity													molecular_function											owl:Class	
GO:0015573	biolink:NamedThing	beta-glucoside transmembrane transporter activity	Enables the transfer of beta-glucosides from one side of a membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.	got7fsn_ti	beta-glucoside permease activity										GO:0015582			molecular_function											owl:Class	
GO:0018402	biolink:NamedThing	protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.	got7fsn_ti	protein-chondroitin sulphate linkage via chondroitin sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine											RESID:AA0208		biological_process											owl:Class	
GO:0004484	biolink:NamedThing	mRNA guanylyltransferase activity	Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.	got7fsn_ti	protein lambda2|mRNA capping enzyme activity|GTP--RNA guanylyltransferase activity|messenger RNA guanylyltransferase activity|GTP:mRNA guanylyltransferase activity											Reactome:R-HSA-77083|EC:2.7.7.50|RHEA:54592|MetaCyc:MRNA-GUANYLYLTRANSFERASE-RXN|Reactome:R-HSA-77081		molecular_function											owl:Class	
GO:0031817	biolink:NamedThing	P2Y8 nucleotide receptor binding	Binding to a P2Y8 nucleotide receptor.	got7fsn_ti	P2Y8 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0034382	biolink:NamedThing	chylomicron remnant clearance	The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.	got7fsn_ti														biological_process											owl:Class	
GO:0071830	biolink:NamedThing	triglyceride-rich lipoprotein particle clearance	The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							mah	2010-09-08T11:23:55Z						biological_process											owl:Class	
GO:0002681	biolink:NamedThing	somatic recombination of T cell receptor gene segments	The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments.	got7fsn_ti	somatic recombination of TCR gene segments													biological_process											owl:Class	
GO:0047908	biolink:NamedThing	fusarinine-C ornithinesterase activity	Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol.	got7fsn_ti	5-N-acyl-L-ornithine-ester hydrolase activity|N5-acyl-L-ornithine-ester hydrolase activity|ornithine esterase activity											RHEA:20165|EC:3.1.1.48|MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN		molecular_function											owl:Class	
GO:0102478	biolink:NamedThing	beta-L-arabinofuranosidase activity	Catalysis of the reaction: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose.	got7fsn_ti												RHEA:36051|EC:3.2.1.185|MetaCyc:RXN-14089		molecular_function											owl:Class	
GO:0019373	biolink:NamedThing	epoxygenase P450 pathway	The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.	got7fsn_ti														biological_process											owl:Class	
GO:0099624	biolink:NamedThing	atrial cardiac muscle cell membrane repolarization	The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.	got7fsn_ti														biological_process											owl:Class	
GO:0102383	biolink:NamedThing	steviol 19-O glucosyltransferase activity	Catalysis of the reaction: steviol + UDP-alpha-D-glucose <=> 19-O-beta-glucopyranosyl-steviol + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13520		molecular_function											owl:Class	
GO:0003293	biolink:NamedThing	heart valve cell differentiation	The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve.	got7fsn_ti							dph	2009-10-20T11:06:46Z						biological_process											owl:Class	
GO:0014025	biolink:NamedThing	neural keel formation	The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.	got7fsn_ti														biological_process											owl:Class	
GO:0097297	biolink:NamedThing	activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the execution phase of apoptosis.	got7fsn_ti	activation of effector caspase activity				Note that this term should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the execution phase of apoptosis (also known as an effector caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process.		pr	2012-05-02T03:23:01Z						biological_process											owl:Class	
GO:2001272	biolink:NamedThing	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.	got7fsn_ti	positive regulation of effector caspase activity						pr	2011-12-13T07:59:47Z						biological_process											owl:Class	
GO:0072056	biolink:NamedThing	pyramid development	The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.	got7fsn_ti	kidney pyramid development|renal medulla development|pyramids development|renal pyramid development						mah	2010-01-25T04:01:36Z						biological_process											owl:Class	
GO:0052075	biolink:NamedThing	positive regulation by symbiont of host jasmonic acid-mediated defense response	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	up-regulation by symbiont of host jasmonic acid-mediated defense response|induction by organism of host jasmonic acid-mediated defense response|activation by symbiont of host jasmonic acid-mediated defense response|induction by organism of host JA-mediated defense response|positive regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|upregulation by symbiont of host jasmonic acid-mediated defense response|up regulation by symbiont of host jasmonic acid-mediated defense response|positive regulation by organism of host JA-mediated defense response|stimulation by symbiont of host jasmonic acid-mediated defense response										GO:0052273			biological_process											owl:Class	
GO:0005314	biolink:NamedThing	high-affinity glutamate transmembrane transporter activity	Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high-affinity glutamate transporter activity											Reactome:R-HSA-210404|Reactome:R-HSA-428015|Reactome:R-HSA-5625015|Reactome:R-HSA-5625029		molecular_function											owl:Class	
GO:0015370	biolink:NamedThing	solute:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in).	got7fsn_ti	proline/glycine/betaine:hydrogen/sodium symporter activity											Reactome:R-HSA-8876283		molecular_function											owl:Class	
GO:0000243	biolink:NamedThing	commitment complex	A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.	got7fsn_ti	mammalian spliceosomal complex E|yeast spliceosomal complex CC|mammalian spliceosomal E complex													cellular_component											owl:Class	
GO:0004610	biolink:NamedThing	phosphoacetylglucosamine mutase activity	Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.	got7fsn_ti	phospho-N-acetylglucosamine mutase activity|N-acetyl-D-glucosamine 1,6-phosphomutase activity|N-acetylglucosamine-phosphate mutase activity|acetylaminodeoxyglucose phosphomutase activity|acetylglucosamine phosphomutase activity|N-acetyl-alpha-D-glucosamine 1,6-phosphomutase activity											MetaCyc:PHOSACETYLGLUCOSAMINEMUT-RXN|Reactome:R-HSA-446185|RHEA:23804|EC:5.4.2.3|KEGG_REACTION:R08193		molecular_function											owl:Class	
GO:1990209	biolink:NamedThing	negative regulation by symbiont of RNA levels in host	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-09T18:09:33Z						biological_process											owl:Class	
GO:0033846	biolink:NamedThing	adenosyl-fluoride synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.	got7fsn_ti	fluorinase activity|S-adenosyl-L-methionine:fluoride adenosyltransferase activity											MetaCyc:2.5.1.63-RXN|RHEA:16661|EC:2.5.1.63		molecular_function											owl:Class	
GO:0034598	biolink:NamedThing	phosphothreonine lyase activity	Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product.	got7fsn_ti														molecular_function											owl:Class	
GO:0015826	biolink:NamedThing	threonine transport	The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-threonine transport													biological_process											owl:Class	
GO:0090471	biolink:NamedThing	9,15,9'-tri-cis-zeta-carotene isomerase activity	Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene.	got7fsn_ti	9,15,9'-tricis-zeta-carotene cis-trans-isomerase						tb	2012-09-24T16:29:49Z						molecular_function											owl:Class	
GO:0034056	biolink:NamedThing	estrogen response element binding	Binding to an estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.	got7fsn_ti	ERE binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.									molecular_function											owl:Class	
GO:0031390	biolink:NamedThing	Ctf18 RFC-like complex	A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p.	got7fsn_ti	RFC (Ctf18)|Ctf18-RLC|Ctf18-RFC													cellular_component											owl:Class	
GO:0050158	biolink:NamedThing	orotate reductase (NADPH) activity	Catalysis of the reaction: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate.	got7fsn_ti	dihydro-orotic dehydrogenase activity|orotate reductase activity|L-5,6-dihydro-orotate:NAD oxidoreductase activity|(S)-dihydroorotate:NADP+ oxidoreductase activity											KEGG_REACTION:R01866|RHEA:14861|EC:1.3.1.15|MetaCyc:OROTATE-REDUCTASE-NADPH-RXN		molecular_function											owl:Class	
GO:0050589	biolink:NamedThing	leucocyanidin oxygenase activity	Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.	got7fsn_ti	leucoanthocyanidin hydroxylase|leucoanthocyanidin dioxygenase activity|leucocyanidin,2-oxoglutarate:oxygen oxidoreductase activity|anthocyanidin synthase activity										GO:0045432	EC:1.14.20.4|MetaCyc:RXN-602		molecular_function											owl:Class	
GO:0030369	biolink:NamedThing	ICAM-3 receptor activity	Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues.	got7fsn_ti					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'cell adhesion molecule binding ; GO:0050839' and 'receptor binding ; GO:0005102' and the biological process term 'cell adhesion ; GO:0007155'.									molecular_function											owl:Class	
GO:0090711	biolink:NamedThing	FMN hydrolase activity	Catalysis of the reaction: FMN + H2O = riboflavin + phosphate.	got7fsn_ti							tb	2016-10-21T16:27:34Z						molecular_function											owl:Class	
GO:0006563	biolink:NamedThing	L-serine metabolic process	The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.	got7fsn_ti	L-serine metabolism													biological_process											owl:Class	
GO:0072313	biolink:NamedThing	metanephric glomerular epithelial cell development	The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.	got7fsn_ti							mah	2010-04-09T06:57:26Z						biological_process											owl:Class	
GO:0033167	biolink:NamedThing	ARC complex	A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA.	got7fsn_ti	argonaute siRNA chaperone complex													cellular_component											owl:Class	
GO:0004640	biolink:NamedThing	phosphoribosylanthranilate isomerase activity	Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.	got7fsn_ti	IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex)|N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase activity|PRA isomerase activity|N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase activity|PRAI activity|N-(5'-phosphoribosyl)anthranilate isomerase activity											MetaCyc:PRAISOM-RXN|KEGG_REACTION:R03509|RHEA:21540|EC:5.3.1.24		molecular_function											owl:Class	
GO:0033372	biolink:NamedThing	establishment of protease localization to mast cell secretory granule	The directed movement of a protease to a location within a secretory granule in a mast cell.	got7fsn_ti	establishment of protease localisation in mast cell secretory granule|establishment of protease localization in mast cell secretory granule													biological_process											owl:Class	
GO:0033369	biolink:NamedThing	establishment of protein localization to mast cell secretory granule	The directed movement of a protein to a location within a secretory granule in a mast cell.	got7fsn_ti	establishment of protein localisation in mast cell secretory granule|establishment of protein localization in mast cell secretory granule													biological_process											owl:Class	
GO:0072464	biolink:NamedThing	response to meiotic spindle assembly checkpoint signaling	A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling.	got7fsn_ti	response to signal involved in meiotic spindle assembly checkpoint|meiotic spindle assembly checkpoint effector process						mah	2010-12-09T11:37:48Z						biological_process											owl:Class	
GO:0015389	biolink:NamedThing	pyrimidine- and adenine-specific:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0005345	biolink:NamedThing	purine nucleobase transmembrane transporter activity	Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.	got7fsn_ti	purine base transmembrane transporter activity|purine transmembrane transporter activity													molecular_function											owl:Class	
GO:0090138	biolink:NamedThing	regulation of actin cytoskeleton organization by cell-cell adhesion	Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.	got7fsn_ti	regulation of actin cytoskeleton organisation by cell-cell adhesion						tb	2009-12-08T02:05:00Z						biological_process											owl:Class	
GO:0035583	biolink:NamedThing	sequestering of TGFbeta in extracellular matrix	Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins.	got7fsn_ti	negative regulation of transforming growth factor beta receptor signalling pathway by extracellular matrix sequestering of TGFbeta|sequestering of TGFbeta LLC in extracellular matrix|negative regulation of transforming growth factor beta receptor signaling pathway by extracellular matrix sequestering of TGFbeta|sequestering of TGFbeta large latency complex in extracellular matrix						bf	2010-10-12T03:13:29Z						biological_process											owl:Class	
GO:0099607	biolink:NamedThing	lateral attachment of mitotic spindle microtubules to kinetochore	The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).	got7fsn_ti														biological_process											owl:Class	
GO:0051315	biolink:NamedThing	attachment of mitotic spindle microtubules to kinetochore	The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.	got7fsn_ti	attachment of spindle microtubules to mitotic chromosome|attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|mitotic bipolar attachment|attachment of spindle microtubules to kinetochore during mitosis|attachment of spindle microtubules to kinetochore involved in mitosis				This class covers transient, lateral attachment to microtubules as well as stable, correctly oriented, end-on attachment (biorientation)						GO:0051314			biological_process											owl:Class	
GO:0034950	biolink:NamedThing	phenylboronic acid monooxygenase activity	Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3.	got7fsn_ti												UM-BBD_reactionID:r1020		molecular_function											owl:Class	
GO:0034805	biolink:NamedThing	benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity	Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1121		molecular_function											owl:Class	
GO:0060031	biolink:NamedThing	mediolateral intercalation	The interdigitation of cells along the mediolateral axis during gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0097211	biolink:NamedThing	cellular response to gonadotropin-releasing hormone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.	got7fsn_ti	cellular response to gonadotrophin-releasing hormone|cellular response to GnRH						pr	2012-01-09T08:51:23Z						biological_process											owl:Class	
GO:0097210	biolink:NamedThing	response to gonadotropin-releasing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.	got7fsn_ti	response to GnRH						pr	2012-01-09T08:48:56Z						biological_process											owl:Class	
GO:0019126	biolink:NamedThing	peptidyl-serine racemization	The racemization of peptidyl-serine.	got7fsn_ti											GO:0018090|GO:0018372	RESID:AA0195		biological_process											owl:Class	
GO:0006208	biolink:NamedThing	pyrimidine nucleobase catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.	got7fsn_ti	pyrimidine base degradation|pyrimidine base catabolic process|pyrimidine base breakdown|pyrimidine base catabolism													biological_process											owl:Class	
GO:0009113	biolink:NamedThing	purine nucleobase biosynthetic process	The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.	got7fsn_ti	purine base anabolism|purine base biosynthetic process|purine base biosynthesis|purine base synthesis|purine base formation											MetaCyc:PWY-841		biological_process											owl:Class	
GO:0071739	biolink:NamedThing	IgD immunoglobulin complex, circulating	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti	IgD antibody				Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0071738	biolink:NamedThing	IgD immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti					Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0033921	biolink:NamedThing	capsular-polysaccharide endo-1,3-alpha-galactosidase activity	Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.	got7fsn_ti	polysaccharide depolymerase activity|capsular polysaccharide galactohydrolase activity|aerobacter-capsular-polysaccharide galactohydrolase activity											MetaCyc:3.2.1.87-RXN|EC:3.2.1.87		molecular_function											owl:Class	
GO:0050265	biolink:NamedThing	RNA uridylyltransferase activity	Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).	got7fsn_ti	TUT activity|polynucleotide uridylyltransferase activity|poly(U) polymerase activity|UTP:RNA uridylyltransferase activity|terminal uridylyltransferase activity											Reactome:R-HSA-8941312|RHEA:14785|EC:2.7.7.52|MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0045300	biolink:NamedThing	acyl-[acyl-carrier-protein] desaturase activity	Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin.	got7fsn_ti	stearyl acyl carrier protein desaturase activity|acyl-[acyl-carrier protein] desaturase activity|stearyl-ACP desaturase activity|acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity|acyl-acyl-carrier-protein desaturase activity				Note that this function was formerly EC:1.14.99.6.							MetaCyc:1.14.19.2-RXN|MetaCyc:PWY-5147|EC:1.14.19.2		molecular_function											owl:Class	
GO:0097575	biolink:NamedThing	lateral cell cortex	The region directly beneath the plasma membrane of the lateral portion of the cell.	got7fsn_ti							pr	2014-02-26T13:29:22Z						cellular_component											owl:Class	
GO:0110130	biolink:NamedThing	ribitol-5-phosphatase activity	Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate.	got7fsn_ti							kmv	2018-10-08T19:47:57Z				RHEA:47648		molecular_function											owl:Class	
GO:0102246	biolink:NamedThing	6-amino-6-deoxyfutalosine hydrolase activity	Catalysis of the reaction: aminodeoxyfutalosinate + H2O <=> dehypoxanthine futalosine + adenine.	got7fsn_ti												MetaCyc:RXN-12346|EC:3.2.2.30|RHEA:33079		molecular_function											owl:Class	
GO:0051684	biolink:NamedThing	maintenance of Golgi location	Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of Golgi apparatus localization|maintenance of Golgi localization|maintenance of Golgi body localization													biological_process											owl:Class	
GO:0044812	biolink:NamedThing	fermentative hydrogen production	The fermentation of organic substances with a net release of hydrogen.	got7fsn_ti	carbohydrate fermentation						jl	2013-09-18T14:09:47Z				Wikipedia:Fermentative_hydrogen_production		biological_process											owl:Class	
GO:0071491	biolink:NamedThing	cellular response to red light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti	cellular response to red light stimulus						mah	2009-12-18T02:19:47Z						biological_process											owl:Class	
GO:0097392	biolink:NamedThing	chemokine (C-X-C motif) ligand 16 production	The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CXCL16 production						pr	2012-10-23T07:59:43Z						biological_process											owl:Class	
GO:0018043	biolink:NamedThing	C-terminal peptidyl-isoleucine amidation	The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0090		biological_process											owl:Class	
GO:0050535	biolink:NamedThing	beta-primeverosidase activity	Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.	got7fsn_ti	6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside 6-O-(beta-D-xylosyl)-beta-D-glucohydrolase activity|b-primeverosidase activity											RHEA:24480|EC:3.2.1.149|MetaCyc:3.2.1.149-RXN		molecular_function											owl:Class	
GO:0071171	biolink:NamedThing	site-specific DNA replication termination at RTS1 barrier	A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.	got7fsn_ti							mah	2009-11-20T01:24:41Z						biological_process											owl:Class	
GO:0062048	biolink:NamedThing	lymphotoxin complex	A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations.	got7fsn_ti	lymphotoxin alpha-beta						dph	2018-05-18T18:34:55Z						cellular_component											owl:Class	
GO:0034692	biolink:NamedThing	E.F.G complex	A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0061803	biolink:NamedThing	posterior cell cortex	The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis.	got7fsn_ti							dph	2016-11-06T22:55:45Z						cellular_component											owl:Class	
GO:0045838	biolink:NamedThing	positive regulation of membrane potential	Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	got7fsn_ti	upregulation of membrane potential|up-regulation of membrane potential|stimulation of membrane potential|elevation of membrane potential|up regulation of membrane potential|activation of membrane potential													biological_process											owl:Class	
GO:0045857	biolink:NamedThing	negative regulation of molecular function, epigenetic	Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.	got7fsn_ti	inhibition of protein activity, epigenetic|downregulation of protein activity, epigenetic|negative regulation of protein activity, epigenetic|down regulation of protein activity, epigenetic|down-regulation of protein activity, epigenetic													biological_process											owl:Class	
GO:0102449	biolink:NamedThing	kaempferol 3-O-methyltransferase activity	Catalysis of the reaction: kaempferol oxoanion + S-adenosyl-L-methionine  <=> 3-O-methylkaempferol + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13935		molecular_function											owl:Class	
GO:0009976	biolink:NamedThing	tocopherol cyclase activity	Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol).	got7fsn_ti														molecular_function											owl:Class	
GO:0043638	biolink:NamedThing	puromycin biosynthetic process	The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.	got7fsn_ti														biological_process											owl:Class	
GO:0098818	biolink:NamedThing	hyperpolarization of postsynaptic membrane	A process that hyerpolarizes a postsynaptic membrane relative to its resting potential.  This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold.	got7fsn_ti														biological_process											owl:Class	
GO:1900511	biolink:NamedThing	positive regulation of pentose catabolic process to ethanol	Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol.	got7fsn_ti	up-regulation of pentose catabolism to ethanol|activation of pentose catabolic process to ethanol|positive regulation of pentose catabolism to ethanol|activation of pentose catabolism to ethanol|up regulation of pentose catabolic process to ethanol|upregulation of pentose catabolism to ethanol|up-regulation of pentose catabolic process to ethanol|up regulation of pentose catabolism to ethanol|upregulation of pentose catabolic process to ethanol						tt	2012-05-02T04:05:01Z						biological_process											owl:Class	
GO:0033063	biolink:NamedThing	Rad51B-Rad51C-Rad51D-XRCC2 complex	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof.	got7fsn_ti	BCDX2 complex													cellular_component											owl:Class	
GO:0047162	biolink:NamedThing	17-O-deacetylvindoline O-acetyltransferase activity	Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA.	got7fsn_ti	acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase activity|DAT activity|acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase activity|deacetylvindoline O-acetyltransferase activity|acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase activity|17-O-deacetylvindoline-17-O-acetyltransferase activity|acetyl-CoA:deacetylvindoline 4-O-acetyltransferase activity|deacetylvindoline acetyltransferase activity|acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase activity|acetylcoenzyme A:deacetylvindoline O-acetyltransferase activity											EC:2.3.1.107|MetaCyc:2.3.1.107-RXN|RHEA:24496|KEGG_REACTION:R03230		molecular_function											owl:Class	
GO:0048673	biolink:NamedThing	collateral sprouting of intact axon in response to injury	The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input.	got7fsn_ti														biological_process											owl:Class	
GO:0090275	biolink:NamedThing	negative regulation of somatostatin secretion	Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.	got7fsn_ti							tb	2010-02-05T02:54:14Z						biological_process											owl:Class	
GO:0090273	biolink:NamedThing	regulation of somatostatin secretion	Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.	got7fsn_ti							tb	2010-02-05T02:54:14Z						biological_process											owl:Class	
GO:0120001	biolink:NamedThing	apical plasma membrane urothelial plaque	A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.	got7fsn_ti	AUM|asymmetric unit membrane	https://github.com/geneontology/go-ontology/issues/12996					krc	2017-02-23T21:10:27Z						cellular_component											owl:Class	
GO:0043554	biolink:NamedThing	aerobic respiration, using arsenite as electron donor	The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems.	got7fsn_ti														biological_process											owl:Class	
GO:0000979	biolink:NamedThing	RNA polymerase II core promoter sequence-specific DNA binding	Binding to a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.	got7fsn_ti							krc	2010-08-10T02:17:28Z						molecular_function											owl:Class	
GO:0102434	biolink:NamedThing	pterin-4alpha-carbinolamine dehydratase activity	Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.	got7fsn_ti												MetaCyc:RXN-13908		molecular_function											owl:Class	
GO:0043124	biolink:NamedThing	negative regulation of I-kappaB kinase/NF-kappaB signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.	got7fsn_ti	down-regulation of I-kappaB kinase/NF-kappaB cascade|down regulation of I-kappaB kinase/NF-kappaB cascade|inhibition of I-kappaB kinase/NF-kappaB cascade|downregulation of I-kappaB kinase/NF-kappaB cascade|negative regulation of I-kappaB kinase/NF-kappaB cascade													biological_process											owl:Class	
GO:0031517	biolink:NamedThing	red light photoreceptor activity	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.	got7fsn_ti														molecular_function											owl:Class	
GO:0030061	biolink:NamedThing	mitochondrial crista	Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria.	got7fsn_ti	mitochondrial cristae|cristae				See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.							NIF_Subcellular:sao333328131		cellular_component											owl:Class	
GO:0033835	biolink:NamedThing	flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity	Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside].	got7fsn_ti	UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase activity|1->2 UDP-rhamnosyltransferase activity|UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity											MetaCyc:RXN-7759|MetaCyc:RXN-5002|EC:2.4.1.236|MetaCyc:RXN-9699|RHEA:15473|MetaCyc:RXN-5004|MetaCyc:RXN-5001		molecular_function											owl:Class	
GO:0102513	biolink:NamedThing	delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + vanillate + H+.	got7fsn_ti												MetaCyc:RXN-14442		molecular_function											owl:Class	
GO:0010852	biolink:NamedThing	cyclase inhibitor activity	Decreases the activity of an enzyme that catalyzes a ring closure reaction.	got7fsn_ti														molecular_function											owl:Class	
GO:0019143	biolink:NamedThing	3-deoxy-manno-octulosonate-8-phosphatase activity	Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate.	got7fsn_ti	3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase activity											MetaCyc:KDO-8PPHOSPHAT-RXN|RHEA:11500|EC:3.1.3.45|KEGG_REACTION:R03350		molecular_function											owl:Class	
GO:0097098	biolink:NamedThing	DNA/RNA hybrid annealing activity	An activity that facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/2161					pr	2011-07-07T11:20:44Z						molecular_function											owl:Class	
GO:0071667	biolink:NamedThing	DNA/RNA hybrid binding	Binding to a RNA/DNA hybrid.	got7fsn_ti	RNA/DNA hybrid binding						mah	2010-02-15T01:51:44Z						molecular_function											owl:Class	
GO:0008835	biolink:NamedThing	diaminohydroxyphosphoribosylaminopyrimidine deaminase activity	Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(2)O + H(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NH(4)(+).	got7fsn_ti	2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase activity|2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate deaminase activity|2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase activity										GO:0008485	RHEA:21868|KEGG_REACTION:R03459|EC:3.5.4.26|MetaCyc:RIBOFLAVINSYNDEAM-RXN		molecular_function											owl:Class	
GO:0042396	biolink:NamedThing	phosphagen biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.	got7fsn_ti	phosphagen synthesis|phosphagen formation|phosphagen anabolism|phosphagen biosynthesis													biological_process											owl:Class	
GO:0090165	biolink:NamedThing	regulation of secretion by asymmetric Golgi ribbon formation	The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell.	got7fsn_ti							tb	2009-12-08T09:05:16Z						biological_process											owl:Class	
GO:0051525	biolink:NamedThing	NFAT protein binding	Binding to NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.	got7fsn_ti	NFAT4 protein binding|non-calcium-regulated NFAT protein binding|NFAT1 protein binding|NFATc2 binding|NFAT2 protein binding|NFATc4 binding|NFATc1 binding|NFAT5 protein binding|NFAT binding|NFATp binding|NFATc3 binding|NFATc binding|NFATx binding|NFAT3 protein binding|nuclear factor of activated T cell protein binding										GO:0051530|GO:0051528|GO:0051526|GO:0051527|GO:0051529			molecular_function											owl:Class	
GO:0035092	biolink:NamedThing	sperm chromatin condensation	The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.	got7fsn_ti														biological_process											owl:Class	
GO:0036426	biolink:NamedThing	ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity	Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP.	got7fsn_ti							bf	2013-09-16T13:21:01Z				KEGG_REACTION:R07257|MetaCyc:2.4.1.54-RXN		molecular_function											owl:Class	
GO:0030339	biolink:NamedThing	fatty-acyl-ethyl-ester synthase activity	Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol.	got7fsn_ti	fatty-acyl ethyl ester synthase|FAEES activity|long-chain-fatty-acyl-ethyl-ester acylhydrolase activity|FAEE synthase activity											RHEA:16641|EC:3.1.1.67|MetaCyc:FATTY-ACYL-ETHYL-ESTER-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0120206	biolink:NamedThing	photoreceptor distal connecting cilium	The distal region of the photoreceptor connecting cilium is structurally unique to the photoreceptor and is maintained by retina-specific protein, SPATA7, and its interacting partners RPGR and RPGRIP1. It is essential for photoreceptor sensory cilium stability.	got7fsn_ti	DCC|photoreceptor DCC						krc	2019-05-10T22:54:05Z						cellular_component											owl:Class	
GO:0018646	biolink:NamedThing	1-hydroxy-2-oxolimonene 1,2-monooxygenase activity	Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate.	got7fsn_ti												UM-BBD_reactionID:r0736|EC:1.14.13.-		molecular_function											owl:Class	
GO:0030781	biolink:NamedThing	6-O-methylnorlaudanosoline 5'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.	got7fsn_ti	S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase activity											RHEA:11892|EC:2.1.1.121|MetaCyc:2.1.1.121-RXN		molecular_function											owl:Class	
GO:0006123	biolink:NamedThing	mitochondrial electron transport, cytochrome c to oxygen	The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.	got7fsn_ti	complex IV (reduction of O2)													biological_process											owl:Class	
GO:0038124	biolink:NamedThing	toll-like receptor TLR6:TLR2 signaling pathway	A series of molecular signals initiated by the binding of a heterodimeric TLR6:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	toll-like receptor TLR6:TLR2 signalling pathway|TLR2:TLR6 signaling pathway						bf	2012-03-23T10:29:09Z						biological_process											owl:Class	
GO:0034838	biolink:NamedThing	menthone dehydrogenase activity	Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r1183		molecular_function											owl:Class	
GO:0044164	biolink:NamedThing	host cell cytosol	The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	got7fsn_ti	host cytosol						jl	2009-09-04T11:03:27Z						cellular_component											owl:Class	
GO:0070471	biolink:NamedThing	uterine smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.	got7fsn_ti	myometrium contraction|myometrial contraction|myometrial smooth muscle contraction													biological_process											owl:Class	
GO:0050101	biolink:NamedThing	mimosinase activity	Catalysis of the reaction: L-mimosine + H(2)O = 3-hydroxy-4H-pyrid-4-one + L-serine.	got7fsn_ti	mimosine amidohydrolase activity											MetaCyc:MIMOSINASE-RXN|KEGG_REACTION:R04350|RHEA:13373|EC:3.5.1.61		molecular_function											owl:Class	
GO:0106265	biolink:NamedThing	THPH synthase activity	Catalysis of the reaction: 3 H+ + hexanoyl-CoA + 3 malonyl-CoA = 2,4,6-trihydroxyphenylhexan-1-one + 3 CO2 + 4 CoA.	got7fsn_ti	polyketide syntase						hjd	2020-06-02T18:05:33Z				RHEA:64352		molecular_function											owl:Class	
GO:0002490	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent|TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway|TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway													biological_process											owl:Class	
GO:0045040	biolink:NamedThing	protein insertion into mitochondrial outer membrane	The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.	got7fsn_ti	protein import into mitochondrial outer membrane|mitochondrial outer membrane protein import|protein transport into mitochondrial outer membrane													biological_process											owl:Class	
GO:0003994	biolink:NamedThing	aconitate hydratase activity	Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.	got7fsn_ti	aconitase activity|citrate(isocitrate) hydro-lyase activity|citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|cis-aconitase activity|citrate hydro-lyase activity				This is a process composed of two reactions represented by the terms 'GO:0052632 : citrate hydro-lyase (cis-aconitate-forming) activity' and 'GO:0052633 : isocitrate hydro-lyase (cis-aconitate-forming) activity'.							Reactome:R-HSA-70971|Reactome:R-HSA-5690911|EC:4.2.1.3|RHEA:10336|Reactome:R-HSA-450975		molecular_function											owl:Class	
GO:0047342	biolink:NamedThing	galactose-1-phosphate thymidylyltransferase activity	Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose.	got7fsn_ti	dTDP-galactose pyrophosphorylase activity|dTDP galactose pyrophosphorylase activity|thymidine diphosphogalactose pyrophosphorylase activity|dTDP-galactose diphosphorylase activity|galactose 1-phosphate thymidylyl transferase activity|thymidine triphosphate:alpha-D-galactose 1-phosphate thymidylyltransferase activity|dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase activity											EC:2.7.7.32|MetaCyc:2.7.7.32-RXN|KEGG_REACTION:R02329|RHEA:17165		molecular_function											owl:Class	
GO:0003688	biolink:NamedThing	DNA replication origin binding	Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.	got7fsn_ti	ARS binding													molecular_function											owl:Class	
GO:0102309	biolink:NamedThing	dTDP-4-oxo-2,6-dideoxy-D-glucose 4-ketoreductase (dTDP-D-oliose producing) activity	Catalysis of the reaction: dTDP-D-oliose + NADP <=> dTDP-4-dehydro-2,6-dideoxy-D-glucose + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-12930		molecular_function											owl:Class	
GO:0010452	biolink:NamedThing	histone H3-K36 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone.	got7fsn_ti	histone H3 K36 methylation|histone lysine H3 K36 methylation|histone H3K36me													biological_process											owl:Class	
GO:0071816	biolink:NamedThing	tail-anchored membrane protein insertion into ER membrane	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.	got7fsn_ti	protein insertion of tail-anchored membrane proteins into ER membrane|type II transmembrane protein insertion into ER membrane|tail-anchored membrane protein insertion into endoplasmic reticulum membrane						mah	2010-09-06T04:55:16Z						biological_process											owl:Class	
GO:0007545	biolink:NamedThing	processes downstream of sex determination signal	The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways.	got7fsn_ti														biological_process											owl:Class	
GO:0046284	biolink:NamedThing	anthocyanin-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.	got7fsn_ti	anthocyanin catabolic process|anthocyanin breakdown|anthocyanin degradation|anthocyanin catabolism													biological_process											owl:Class	
GO:0070773	biolink:NamedThing	protein-N-terminal glutamine amidohydrolase activity	Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein.	got7fsn_ti	NtQ-amidase activity						mah	2009-06-30T11:34:08Z						molecular_function											owl:Class	
GO:0005611	biolink:NamedThing	laminin-6 complex	A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.	got7fsn_ti	laminin-311 complex|laminin-6A complex													cellular_component											owl:Class	
GO:0034738	biolink:NamedThing	lanosterol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester.	got7fsn_ti														molecular_function											owl:Class	
GO:0097627	biolink:NamedThing	high-affinity L-ornithine transmembrane transporter activity	Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity L-ornithine transmembrane transporter activity						pr	2014-08-20T14:26:33Z						molecular_function											owl:Class	
GO:0000064	biolink:NamedThing	L-ornithine transmembrane transporter activity	Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.	got7fsn_ti	histidine/arginine/lysine/ornithine porter activity|L-ornithine transporter activity											Reactome:R-HSA-70634		molecular_function											owl:Class	
GO:0050526	biolink:NamedThing	poly(3-hydroxybutyrate) depolymerase activity	Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5.	got7fsn_ti	poly(HASCL) depolymerase activity|poly(3HB) depolymerase activity|PHB depolymerase activity|poly(HA(SCL)) depolymerase activity|poly[(R)-3-hydroxybutyrate] hydrolase activity|poly(HA) depolymerase activity|poly[(R)-hydroxyalkanoic acid] depolymerase|poly((R)-hydroxyalkanoic acid) depolymerase activity											EC:3.1.1.75|MetaCyc:3.1.1.75-RXN|RHEA:11248		molecular_function											owl:Class	
GO:0034267	biolink:NamedThing	discadenine metabolic process	The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.	got7fsn_ti	discadenine metabolism													biological_process											owl:Class	
GO:0001647	biolink:NamedThing	G protein-coupled cytokinin receptor activity	Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	cytokinin receptor activity, G-protein coupled|G protein coupled cytokinin receptor activity|G-protein coupled cytokinin receptor activity													molecular_function											owl:Class	
GO:0102084	biolink:NamedThing	L-dopa O-methyltransferase activity	Catalysis of the reaction: L-dopa + S-adenosyl-L-methionine  <=> 3-O-methyldopa + S-adenosyl-L-homocysteine + H+.	got7fsn_ti												MetaCyc:RXN-10870|EC:2.1.1.6		molecular_function											owl:Class	
GO:0004110	biolink:NamedThing	corticosteroid side-chain-isomerase activity	Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al.	got7fsn_ti	11-deoxycorticosterone aldose-ketose-isomerase activity|11-deoxycorticosterone ketol-isomerase activity											KEGG_REACTION:R04165|RHEA:17861|EC:5.3.1.21|MetaCyc:CORTICOSTEROID-SIDE-CHAIN-ISOMERASE-RXN		molecular_function											owl:Class	
GO:0033830	biolink:NamedThing	Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.	got7fsn_ti	UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase activity|UDP-N-acetyl-D-glucosamine:Skp1-protein-hydroxyproline N-acetyl-D-glucosaminyl-transferase activity|Skp1-HyPro GlcNAc-transferase activity|UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase activity|UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase activity											EC:2.4.1.229|RHEA:17841		molecular_function											owl:Class	
GO:0018138	biolink:NamedThing	peptide cross-linking via L-serine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	got7fsn_ti												RESID:AA0242		biological_process											owl:Class	
GO:0042590	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class I	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.	got7fsn_ti	cross-priming|cross priming|antigen presentation, exogenous antigen via major histocompatibility complex class I|exogenous peptide antigen processing and presentation via MHC class I|cross-presentation|cross presentation|antigen presentation, exogenous antigen via MHC class I													biological_process											owl:Class	
GO:0060527	biolink:NamedThing	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini.	got7fsn_ti														biological_process											owl:Class	
GO:1990871	biolink:NamedThing	Vma12-Vma22 assembly complex	A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p.	got7fsn_ti							rb	2015-09-28T19:03:28Z						cellular_component											owl:Class	
GO:0052686	biolink:NamedThing	perillic acid-CoA ligase (AMP-forming) activity	Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA.	got7fsn_ti	perillic acid:CoA ligase (AMP-forming) activity|perillyl-CoA synthetase activity											KEGG_REACTION:R06368		molecular_function											owl:Class	
GO:0006293	biolink:NamedThing	nucleotide-excision repair, preincision complex stabilization	The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.	got7fsn_ti														biological_process											owl:Class	
GO:0031334	biolink:NamedThing	positive regulation of protein-containing complex assembly	Any process that activates or increases the frequency, rate or extent of protein complex assembly.	got7fsn_ti	activation of protein complex assembly|up regulation of protein complex assembly|upregulation of protein complex assembly|stimulation of protein complex assembly|positive regulation of protein complex assembly|up-regulation of protein complex assembly													biological_process											owl:Class	
GO:0102311	biolink:NamedThing	8-hydroxygeraniol dehydrogenase activity	Catalysis of the reaction: (6E)-8-hydroxygeraniol + 2 NADP <=> (6E)-8-oxogeranial + 2 NADPH + 2 H+.	got7fsn_ti												EC:1.1.1.324|RHEA:32659|MetaCyc:RXN-12961		molecular_function											owl:Class	
GO:0016980	biolink:NamedThing	creatinase activity	Catalysis of the reaction: creatine + H(2)O = sarcosine + urea.	got7fsn_ti	creatine amidinohydrolase activity											KEGG_REACTION:R01566|RHEA:22456|EC:3.5.3.3|MetaCyc:CREATINASE-RXN		molecular_function											owl:Class	
GO:0031218	biolink:NamedThing	arabinogalactan endo-1,4-beta-galactosidase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans.	got7fsn_ti	endo-1,4-beta-galactanase activity|arabinogalactanase activity|arabinogalactan 4-beta-D-galactanohydrolase activity|galactanase activity											MetaCyc:3.2.1.89-RXN|EC:3.2.1.89		molecular_function											owl:Class	
GO:0102842	biolink:NamedThing	1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity (SN2-16:3 forming)	Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												RHEA:46412|EC:1.14.19.35|MetaCyc:RXN-8303		molecular_function											owl:Class	
GO:0018663	biolink:NamedThing	2,6-dihydroxypyridine 3-monooxygenase activity	Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+).	got7fsn_ti	2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating)|2,6-dihydroxypyridine oxidase activity											RHEA:16917|UM-BBD_reactionID:r0479|EC:1.14.13.10|MetaCyc:1.14.13.10-RXN|KEGG_REACTION:R04130		molecular_function											owl:Class	
GO:0004817	biolink:NamedThing	cysteine-tRNA ligase activity	Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).	got7fsn_ti	cysteinyl-tRNA synthetase activity|cysteinyl-transfer ribonucleate synthetase activity|cysteinyl-transferRNA synthetase activity|L-cysteine:tRNACys ligase (AMP-forming)|cysteine translase activity											EC:6.1.1.16|Reactome:R-HSA-379887|MetaCyc:CYSTEINE--TRNA-LIGASE-RXN|RHEA:17773|Reactome:R-HSA-380158		molecular_function											owl:Class	
GO:0001921	biolink:NamedThing	positive regulation of receptor recycling	Any process that activates or increases the frequency, rate or extent of receptor recycling.	got7fsn_ti	up-regulation of receptor recycling|stimulation of receptor recycling|up regulation of receptor recycling|activation of receptor recycling|upregulation of receptor recycling													biological_process											owl:Class	
GO:0021826	biolink:NamedThing	substrate-independent telencephalic tangential migration	The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact.	got7fsn_ti														biological_process											owl:Class	
GO:0050193	biolink:NamedThing	phosphoketolase activity	Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O.	got7fsn_ti	D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)|xylulose-5-phosphate phosphoketolase activity|D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-acetylating) activity											MetaCyc:PHOSPHOKETOLASE-RXN|RHEA:10468|EC:4.1.2.9		molecular_function											owl:Class	
GO:0045222	biolink:NamedThing	CD4 biosynthetic process	The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions.	got7fsn_ti	CD4 formation|CD4 anabolism|CD4 biosynthesis|CD4 synthesis													biological_process											owl:Class	
GO:0034687	biolink:NamedThing	integrin alphaL-beta2 complex	An integrin complex that comprises one alphaL subunit and one beta2 subunit.	got7fsn_ti	Itgal-Itgb2 complex|alphaL-beta2 integrin complex													cellular_component											owl:Class	
GO:1990839	biolink:NamedThing	response to endothelin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).	got7fsn_ti							sl	2015-08-27T19:37:52Z						biological_process											owl:Class	
GO:0018904	biolink:NamedThing	ether metabolic process	The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds.	got7fsn_ti	organic ether metabolic process|ether metabolism|organic ether metabolism													biological_process											owl:Class	
GO:0006099	biolink:NamedThing	tricarboxylic acid cycle	A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.	got7fsn_ti	TCA cycle|Krebs cycle|citric acid cycle											MetaCyc:P42-PWY|Wikipedia:Tricarboxylic_acid_cycle|MetaCyc:P105-PWY|MetaCyc:TCA		biological_process											owl:Class	
GO:0009379	biolink:NamedThing	Holliday junction helicase complex	A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA.	got7fsn_ti														cellular_component											owl:Class	
GO:1990119	biolink:NamedThing	RNA helicase inhibitor activity	Binds to and stops, prevents or reduces the activity of an RNA helicase.	got7fsn_ti	ATP-dependent RNA helicase inhibitor activity						rb	2013-06-11T21:14:38Z						molecular_function											owl:Class	
GO:0009860	biolink:NamedThing	pollen tube growth	Growth of pollen via tip extension of the intine wall.	got7fsn_ti														biological_process											owl:Class	
GO:0010637	biolink:NamedThing	negative regulation of mitochondrial fusion	Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.	got7fsn_ti														biological_process											owl:Class	
GO:0001770	biolink:NamedThing	establishment of natural killer cell polarity	The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.	got7fsn_ti	NK cell polarization|natural killer cell polarization|establishment of NK cell polarity													biological_process											owl:Class	
GO:0044311	biolink:NamedThing	exoneme	A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte.	got7fsn_ti							jl	2010-02-18T03:29:56Z						cellular_component											owl:Class	
GO:0102371	biolink:NamedThing	betulin dehydrogenase activity	Catalysis of the reaction: betulin + NADPH(4-) + H+ + O2 <=> betulinic aldehyde + NADP(3-) + 2 H2O.	got7fsn_ti												MetaCyc:RXN-13498		molecular_function											owl:Class	
GO:0047561	biolink:NamedThing	3-hydroxyanthranilate oxidase activity	Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H(2)O(2).	got7fsn_ti	3-hydroxyanthranilic acid oxidase activity|3-hydroxyanthranilate:oxygen oxidoreductase activity											KEGG_REACTION:R02666|RHEA:17245|MetaCyc:3-HYDROXYANTHRANILATE-OXIDASE-RXN|EC:1.10.3.5		molecular_function											owl:Class	
GO:0019648	biolink:NamedThing	formaldehyde assimilation via xylulose monophosphate cycle	The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds.	got7fsn_ti	formaldehyde assimilation via xylulose-5-phosphate cycle|formaldehyde fixation cycle											MetaCyc:P185-PWY		biological_process											owl:Class	
GO:0051167	biolink:NamedThing	xylulose 5-phosphate metabolic process	The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway.	got7fsn_ti	xylulose-5-phosphate metabolic process|xylulose-5-phosphate metabolism|D-xylulose 5-phosphate metabolic process|D-xylulose-5-phosphate metabolic process|xylulose 5-phosphate metabolism|D-xylulose-5-phosphate metabolism|D-xylulose 5-phosphate metabolism													biological_process											owl:Class	
GO:0032044	biolink:NamedThing	DSIF complex	A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes.	got7fsn_ti	5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex|Spt4-Spt5 complex|DRB sensitivity inducing factor complex|Spt5-Spt4 complex													cellular_component											owl:Class	
GO:0030579	biolink:NamedThing	ubiquitin-dependent SMAD protein catabolic process	The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.	got7fsn_ti	ubiquitin-dependent SMAD protein breakdown|ubiquitin-dependent SMAD protein catabolism|ubiquitin-dependent SMAD protein degradation													biological_process											owl:Class	
GO:0044025	biolink:NamedThing	histone kinase activity (H2B-S14 specific)	Catalysis of the transfer of a phosphate group to the serine-14 or an equivalent residue of the N-terminal tail of histone H2B.	got7fsn_ti	histone-serine kinase activity (H2B-S14 specific)|histone serine kinase activity (H2B-S14 specific)													molecular_function											owl:Class	
GO:0021776	biolink:NamedThing	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.	got7fsn_ti	hedgehog signaling pathway involved in spinal cord motor neuron cell fate specification|hh signaling pathway involved in spinal cord motor neuron cell fate specification|smoothened signalling pathway involved in spinal cord motor neuron cell fate specification													biological_process											owl:Class	
GO:2000212	biolink:NamedThing	negative regulation of glutamate metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process.	got7fsn_ti	negative regulation of glutamate metabolism|negative regulation of glutamic acid metabolic process|negative regulation of glutamic acid metabolism						mah	2010-11-03T02:43:55Z						biological_process											owl:Class	
GO:0016296	biolink:NamedThing	palmitoyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate.	got7fsn_ti	palmitoyl-ACP hydrolase activity|palmitoyl-[acyl-carrier protein] hydrolase activity											KEGG_REACTION:R08162|EC:3.1.2.14|RHEA:41932|MetaCyc:RXN-9549		molecular_function											owl:Class	
GO:0035942	biolink:NamedThing	dehydroepiandrosterone secretion	The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system.	got7fsn_ti	dehydroisoandrosterone secretion|3beta-hydroxyandrost-5-en-17-one secretion|DHEA secretion						bf	2011-07-25T02:13:54Z						biological_process											owl:Class	
GO:0018450	biolink:NamedThing	myrtenol dehydrogenase activity	Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.	got7fsn_ti												UM-BBD_reactionID:r0710		molecular_function											owl:Class	
GO:0036351	biolink:NamedThing	histone H2A-K13 ubiquitination	The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin.	got7fsn_ti	histone H2A ubiquitination (H2A-K13)						bf	2012-09-19T11:48:05Z						biological_process											owl:Class	
GO:0047799	biolink:NamedThing	cyclopentanone monooxygenase activity	Catalysis of the reaction: cyclopentanone + H(+) + NADPH + O(2) = 5-valerolactone + H(2)O + NADP(+).	got7fsn_ti	cyclopentanone oxygenase activity|cyclopentanone 1,2-monooxygenase activity|cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing)											KEGG_REACTION:R02554|MetaCyc:CYCLOPENTANONE-MONOOXYGENASE-RXN|EC:1.14.13.16|RHEA:15737		molecular_function											owl:Class	
GO:0050266	biolink:NamedThing	rosmarinate synthase activity	Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.	got7fsn_ti	4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase activity|caffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase activity|caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase activity|rosmarinic acid synthase activity											EC:2.3.1.140|MetaCyc:ROSMARINATE-SYNTHASE-RXN|RHEA:22344		molecular_function											owl:Class	
GO:0009713	biolink:NamedThing	catechol-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.	got7fsn_ti	catechol formation|catechol biosynthetic process|catechol synthesis|catechol anabolism|catechol biosynthesis													biological_process											owl:Class	
GO:0099511	biolink:NamedThing	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.	got7fsn_ti														molecular_function											owl:Class	
GO:0008791	biolink:NamedThing	arginine N-succinyltransferase activity	Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine.	got7fsn_ti	succinyl-CoA:L-arginine 2-N-succinyltransferase activity|succinyl-CoA:L-arginine N2-succinyltransferase activity|AST activity|arginine and ornithine N2-succinyltransferase activity|AstA|arginine succinyltransferase activity|arginine and ornithine N(2)-succinyltransferase activity|AOST activity											EC:2.3.1.109|MetaCyc:ARGININE-N-SUCCINYLTRANSFERASE-RXN|RHEA:15185		molecular_function											owl:Class	
GO:0062146	biolink:NamedThing	4-chloro-allylglycine synthase activity	Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+).	got7fsn_ti							dph	2019-09-02T16:59:30Z				RHEA:59888		molecular_function											owl:Class	
GO:0102716	biolink:NamedThing	gibberellin A28,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-6547		molecular_function											owl:Class	
GO:0061837	biolink:NamedThing	neuropeptide processing	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide.	got7fsn_ti														biological_process											owl:Class	
GO:0008688	biolink:NamedThing	3-(3-hydroxyphenyl)propionate hydroxylase activity	Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O.	got7fsn_ti												EC:1.14.13.127|MetaCyc:MHPHYDROXY-RXN|RHEA:24785|KEGG_REACTION:R06786		molecular_function											owl:Class	
GO:0048529	biolink:NamedThing	magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity	Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O.	got7fsn_ti	Mg-protoporphyrin IX monomethyl ester oxidative cyclase activity|magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)|Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase activity											EC:1.14.13.81|RHEA:33235		molecular_function											owl:Class	
GO:0048166	biolink:NamedThing	mature follicle stage	The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division.	got7fsn_ti	mammalian oogenesis stage 9													biological_process											owl:Class	
GO:0061719	biolink:NamedThing	glucose catabolic process to pyruvate utilizing ADP	The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions.	got7fsn_ti							dph	2015-06-30T13:23:42Z				MetaCyc:P341-PWY		biological_process											owl:Class	
GO:0004479	biolink:NamedThing	methionyl-tRNA formyltransferase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.	got7fsn_ti	methionyl-tRNA Met formyltransferase activity|N-terminal peptidyl-methionine N-formylation|formylmethionyl-transfer ribonucleic synthetase activity|methionyl-transfer RNA transformylase activity|methionyl ribonucleic formyltransferase activity|mitochondrial N-terminal peptidyl-methionine N-formylation|conversion of met-tRNAf to fmet-tRNA|N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity|methionyl-tRNA transformylase activity|methionyl-transfer ribonucleic transformylase activity|methionyl-transfer ribonucleate methyltransferase activity|N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity|conversion of mitochondrial met-tRNAf to fmet-tRNA|10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity										GO:0070128|GO:0001718	RHEA:24380|Reactome:R-HSA-5389841|MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN|EC:2.1.2.9		molecular_function											owl:Class	
GO:0072398	biolink:NamedThing	signal transduction involved in cytokinesis checkpoint	A signal transduction process that contributes to a cytokinesis checkpoint.	got7fsn_ti							mah	2010-12-08T03:22:21Z			GO:0072419			biological_process											owl:Class	
GO:0060668	biolink:NamedThing	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland.	got7fsn_ti	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signalling						dph	2009-06-01T09:47:56Z						biological_process											owl:Class	
GO:0016761	biolink:NamedThing	cellulose synthase (GDP-forming) activity	Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1).	got7fsn_ti	GDP-glucose-beta-D-glucan glucosyltransferase activity|cellulose synthase (guanosine diphosphate-forming) activity|guanosine diphosphoglucose-cellulose glucosyltransferase activity|guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity|GDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|GDP-glucose-cellulose glucosyltransferase activity|GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity											RHEA:17797|MetaCyc:CELLULOSE-SYNTHASE-GDP-FORMING-RXN|EC:2.4.1.29		molecular_function											owl:Class	
GO:0098536	biolink:NamedThing	deuterosome	A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.	got7fsn_ti							dos	2013-10-22T16:21:19Z						cellular_component											owl:Class	
GO:0061848	biolink:NamedThing	cellular response to cholecystokinin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0055110	biolink:NamedThing	involution involved in gastrulation with mouth forming second	The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0043963	biolink:NamedThing	modulation by symbiont of host adenylate cyclase-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0102463	biolink:NamedThing	quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: quercetin-3-gentiobioside + UDP-L-rhamnose <=> quercetin 3-O-gentiobioside-7-O-rhamnoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-14012		molecular_function											owl:Class	
GO:0016438	biolink:NamedThing	tRNA-queuosine beta-mannosyltransferase activity	Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine.	got7fsn_ti	GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase activity											RHEA:12885|MetaCyc:2.4.1.110-RXN|EC:2.4.1.110		molecular_function											owl:Class	
GO:0000401	biolink:NamedThing	open form four-way junction DNA binding	Binding to a DNA segment containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over.	got7fsn_ti	open form Holliday junction binding													molecular_function											owl:Class	
GO:0004783	biolink:NamedThing	sulfite reductase (NADPH) activity	Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+.	got7fsn_ti	hydrogen-sulfide:NADP+ oxidoreductase activity|H2S-NADP oxidoreductase activity|sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADPH-sulfite reductase activity|sulphite reductase (NADPH) activity|NADPH-dependent sulfite reductase activity|NADPH:sulfite reductase flavoprotein											EC:1.8.1.2|MetaCyc:SULFITE-REDUCT-RXN|RHEA:13801		molecular_function											owl:Class	
GO:0016002	biolink:NamedThing	sulfite reductase activity	Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor.	got7fsn_ti	siroheme sulfite reductase activity|hydrogen-sulfide:(acceptor) oxidoreductase activity|assimilatory-type sulfite reductase activity|hydrogen-sulfide:acceptor oxidoreductase activity|sulphite reductase activity|assimilatory sulfite reductase activity											MetaCyc:SULFITE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0034412	biolink:NamedThing	ascospore wall beta-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.	got7fsn_ti	ascospore wall beta-glucan anabolism|ascospore wall beta-glucan formation|ascospore wall beta-glucan biosynthesis|ascospore wall beta-glucan synthesis													biological_process											owl:Class	
GO:0034531	biolink:NamedThing	2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity	Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde.	got7fsn_ti												UM-BBD_reactionID:r0766		molecular_function											owl:Class	
GO:0030023	biolink:NamedThing	extracellular matrix constituent conferring elasticity	A component of the extracellular matrix that enables the matrix to recoil after transient stretching.	got7fsn_ti	elastin|core extracellular matrix|core matrisome				Extracellular matrix elastin proteins may be annotated to this term. PMID:27009176, PMID:24443019									molecular_function											owl:Class	
GO:0005201	biolink:NamedThing	extracellular matrix structural constituent	The action of a molecule that contributes to the structural integrity of the extracellular matrix.	got7fsn_ti	extracellular matrix glycoprotein|core extracellular matrix|core matrisome				Extracellular matrix glycoproteins may be annotated to this term. PMID:24443019									molecular_function											owl:Class	
GO:1905277	biolink:NamedThing	negative regulation of epithelial tube formation	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation.	got7fsn_ti	down-regulation of epithelial tube formation|inhibition of epithelial tube formation|down regulation of epithelial tube formation|downregulation of epithelial tube formation				An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-06-20T09:35:49Z						biological_process											owl:Class	
GO:0085030	biolink:NamedThing	symbiotic process benefiting host	A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism.	got7fsn_ti	mutualism						jl	2010-07-27T01:25:21Z						biological_process											owl:Class	
GO:0004468	biolink:NamedThing	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.	got7fsn_ti	acetyl-phosphate:L-lysine N6-acetyltransferase activity|lysine N(6)-acetyltransferase activity|acetyl-phosphate:L-lysine 6-N-acetyltransferase activity|lysine N6-acetyltransferase activity|lysine acetyltransferase activity|LAT activity											Reactome:R-HSA-5693001|RHEA:14417|EC:2.3.1.32|MetaCyc:LYSINE-N-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-5618328		molecular_function											owl:Class	
GO:0036498	biolink:NamedThing	IRE1-mediated unfolded protein response	A series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB.	got7fsn_ti	endoplasmic reticulum unfolded protein response; IRE1 signaling|inositol-requiring transmembrane kinase/endonuclease signal transduction|IRE1alpha unfolded protein response|inositol-requiring enzyme 1-mediated unfolded protein response|UPR signaling by IRE1 stress sensor|IRE1 signal transduction pathway|IRE1 signaling in response to endoplasmic reticulum stress|IRE1p unfolded protein response|ERN1-mediated unfolded protein response|IRE1 branch of UPR				Consider also annotating to 'eiF2alpha phosphorylation in response to endoplasmic reticulum stress ; GO:0036492' or its descendants.		bf	2015-02-05T13:12:12Z						biological_process											owl:Class	
GO:0030968	biolink:NamedThing	endoplasmic reticulum unfolded protein response	The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.	got7fsn_ti	SREBP-mediated signalling pathway|ER unfolded protein response|erUPR				Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any response to the presence of unfolded proteins anywhere in the cell or in multicellular organism. Also see 'ER-associated protein catabolic process ; GO:0030433'.									biological_process											owl:Class	
GO:0061523	biolink:NamedThing	cilium disassembly	A cellular process that results in the breakdown of a cilium.	got7fsn_ti	cilium resorption				Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2013-04-18T14:59:59Z						biological_process											owl:Class	
GO:0031796	biolink:NamedThing	type 1 metabotropic GABA receptor binding	Binding to a type 1 metabotropic GABA receptor.	got7fsn_ti	type 1 metabotropic GABA receptor ligand													molecular_function											owl:Class	
GO:0089702	biolink:NamedThing	undecaprenyl-phosphate glucose phosphotransferase activity	Catalysis of the reaction: UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol.	got7fsn_ti														molecular_function											owl:Class	
GO:0003852	biolink:NamedThing	2-isopropylmalate synthase activity	Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).	got7fsn_ti	alpha-isopropylmalate synthetase activity|isopropylmalate synthase activity|isopropylmalate synthetase activity|alpha-IPM synthetase activity|3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity|alpha-isopropylmalic synthetase activity|alpha-isopropylmalate synthase activity|acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)				Note that this function was formerly EC:4.1.3.12.							MetaCyc:2-ISOPROPYLMALATESYN-RXN|RHEA:21524|EC:2.3.3.13|KEGG_REACTION:R01213		molecular_function											owl:Class	
GO:0044231	biolink:NamedThing	host cell presynaptic membrane	A specialized area of membrane of the host axon terminal that faces the plasma membrane of the host neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many host synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.	got7fsn_ti	other organism pre-synaptic membrane|host cell pre-synaptic membrane|other organism presynaptic membrane						jl	2009-12-08T02:11:18Z			GO:0072556			cellular_component											owl:Class	
GO:0072679	biolink:NamedThing	thymocyte migration	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.	got7fsn_ti	immature T-cell migration|thymic lymphocyte migration|immature T cell migration|immature T lymphocyte migration|immature T-lymphocyte migration						mah	2011-02-22T03:47:51Z						biological_process											owl:Class	
GO:0038054	biolink:NamedThing	G protein-coupled estrogen receptor activity	Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G-protein coupled estrogen receptor activity						bf	2011-11-29T04:29:42Z						molecular_function											owl:Class	
GO:0043818	biolink:NamedThing	precorrin-3B synthase activity	Catalysis of the reaction: H(+) + NADH + O(2) + precorrin-3A = H(2)O + NAD(+) + precorrin-3B.	got7fsn_ti	CobG|precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)|precorrin-3X synthase activity											EC:1.14.13.83|KEGG_REACTION:R05217|MetaCyc:R321-RXN|RHEA:17293		molecular_function											owl:Class	
GO:0102172	biolink:NamedThing	4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O.	got7fsn_ti												RHEA:58860|MetaCyc:RXN-11925		molecular_function											owl:Class	
GO:0051970	biolink:NamedThing	negative regulation of transmission of nerve impulse	Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.	got7fsn_ti	down regulation of transmission of nerve impulse|downregulation of transmission of nerve impulse|negative regulation of conduction of nerve impulse|down-regulation of transmission of nerve impulse|inhibition of transmission of nerve impulse													biological_process											owl:Class	
GO:0002047	biolink:NamedThing	phenazine biosynthetic process	The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring.	got7fsn_ti	dibenzo-p-diazine biosynthetic process|azophenylene biosynthesis|azophenylene biosynthetic process|dibenzopyrazine biosynthesis|acridizine biosynthesis|dibenzopyrazine biosynthetic process|acridizine biosynthetic process|dibenzo-p-diazine biosynthesis													biological_process											owl:Class	
GO:0001561	biolink:NamedThing	fatty acid alpha-oxidation	A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.	got7fsn_ti												MetaCyc:PWY-2501		biological_process											owl:Class	
GO:0009675	biolink:NamedThing	high-affinity sulfate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity sulfate:proton symporter activity|high affinity sulfate:hydrogen symporter activity|high affinity sulphate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0005127	biolink:NamedThing	ciliary neurotrophic factor receptor binding	Binding to a ciliary neurotrophic factor receptor.	got7fsn_ti	ciliary neurotrophic factor|ciliary neurotrophic factor receptor ligand													molecular_function											owl:Class	
GO:0044389	biolink:NamedThing	ubiquitin-like protein ligase binding	Binding to a ubiquitin-like protein ligase, such as ubiquitin-ligase.	got7fsn_ti	E3 protein ligase binding|small conjugating protein ligase binding						jl	2011-12-15T04:33:20Z						molecular_function											owl:Class	
GO:0018363	biolink:NamedThing	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium	The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium.	got7fsn_ti	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulphonium|peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium										GO:0019925	RESID:AA0280		biological_process											owl:Class	
GO:0021995	biolink:NamedThing	neuropore closure	The process of joining together the neural folds at either end of the neural tube.	got7fsn_ti														biological_process											owl:Class	
GO:0008594	biolink:NamedThing	photoreceptor cell morphogenesis	The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster.	got7fsn_ti	photoreceptor development													biological_process											owl:Class	
GO:0007321	biolink:NamedThing	sperm displacement	The physical displacement of sperm stored from previous mating encounters.	got7fsn_ti														biological_process											owl:Class	
GO:0090330	biolink:NamedThing	regulation of platelet aggregation	Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.	got7fsn_ti							tb	2010-05-14T10:46:08Z						biological_process											owl:Class	
GO:0031027	biolink:NamedThing	glutamate synthase complex (NADH)	A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0031026	biolink:NamedThing	glutamate synthase complex	A complex that possesses glutamate synthase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0043897	biolink:NamedThing	glucan 1,4-alpha-maltohydrolase activity	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains.	got7fsn_ti	1,4-alpha-D-glucan alpha-maltohydrolase activity|glucan-1,4-alpha-maltohydrolase activity|maltogenic alpha-amylase activity											MetaCyc:3.2.1.133-RXN|EC:3.2.1.133		molecular_function											owl:Class	
GO:0047550	biolink:NamedThing	2-oxoadipate reductase activity	Catalysis of the reaction: 2-hydroxyadipate + NAD(+) = 2-oxoadipate + H(+) + NADH.	got7fsn_ti	alpha-ketoadipate reductase activity|2-hydroxyadipate:NAD+ 2-oxidoreductase activity|2-ketoadipate reductase activity											KEGG_REACTION:R01932|MetaCyc:2-OXOADIPATE-REDUCTASE-RXN|RHEA:14793|EC:1.1.1.172		molecular_function											owl:Class	
GO:0085032	biolink:NamedThing	modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade	Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host NF-kappaB-mediated signal transduction pathway						jl	2010-07-27T02:13:37Z						biological_process											owl:Class	
GO:2000831	biolink:NamedThing	regulation of steroid hormone secretion	Any process that modulates the frequency, rate or extent of steroid hormone secretion.	got7fsn_ti							bf	2011-07-26T08:38:46Z						biological_process											owl:Class	
GO:0070318	biolink:NamedThing	positive regulation of G0 to G1 transition	A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.	got7fsn_ti														biological_process											owl:Class	
GO:0097680	biolink:NamedThing	double-strand break repair via classical nonhomologous end joining	An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).	got7fsn_ti	C-NHEJ|canonical nonhomologous end joining						pr	2014-12-17T15:15:18Z						biological_process											owl:Class	
GO:0046981	biolink:NamedThing	beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids.	got7fsn_ti	UDP-N-acetylglucosamine:beta-D-mannosyl-glycolipid beta-1,3-N-acetylglucosaminyltransferase activity													molecular_function											owl:Class	
GO:0036201	biolink:NamedThing	ent-isokaurene C2-hydroxylase activity	Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.	got7fsn_ti							bf	2012-04-20T02:21:33Z				EC:1.14.14.76|RHEA:56336|KEGG_REACTION:R09861		molecular_function											owl:Class	
GO:0097426	biolink:NamedThing	glial filament	An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes.	got7fsn_ti							pr	2012-11-07T14:59:55Z				NIF_Subcellular:sao1863852493		cellular_component											owl:Class	
GO:0002558	biolink:NamedThing	type I hypersensitivity mediated by mast cells	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.	got7fsn_ti														biological_process											owl:Class	
GO:0002448	biolink:NamedThing	mast cell mediated immunity	Any process involved in the carrying out of an immune response by a mast cell.	got7fsn_ti														biological_process											owl:Class	
GO:0102514	biolink:NamedThing	cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + ferulate + H+.	got7fsn_ti												EC:2.4.1.300|MetaCyc:RXN-14446		molecular_function											owl:Class	
GO:0002503	biolink:NamedThing	peptide antigen assembly with MHC class II protein complex	The binding of a peptide to the antigen binding groove of an MHC class II protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0036059	biolink:NamedThing	nephrocyte diaphragm assembly	The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.	got7fsn_ti							bf	2011-12-12T04:38:40Z						biological_process											owl:Class	
GO:0034333	biolink:NamedThing	adherens junction assembly	The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	got7fsn_ti	adherens junction formation													biological_process											owl:Class	
GO:0045860	biolink:NamedThing	positive regulation of protein kinase activity	Any process that activates or increases the frequency, rate or extent of protein kinase activity.	got7fsn_ti	up regulation of protein kinase activity|upregulation of protein kinase activity|up-regulation of protein kinase activity|stimulation of protein kinase activity													biological_process											owl:Class	
GO:0070674	biolink:NamedThing	hypoxanthine dehydrogenase activity	Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+.	got7fsn_ti	hypoxanthine-NAD oxidoreductase activity|hypoxanthine/NAD(+) oxidoreductase activity|hypoxanthine:NAD+ oxidoreductase activity|NAD-hypoxanthine dehydrogenase activity|hypoxanthine/NAD+ oxidoreductase activity|hypoxanthine oxidoreductase activity						mah	2009-05-29T01:02:13Z						molecular_function											owl:Class	
GO:0005858	biolink:NamedThing	axonemal dynein complex	A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.	got7fsn_ti	axonemal dynein heavy chain|axonemal dynein intermediate chain|axonemal dynein light chain|axonemal dynein intermediate light chain													cellular_component											owl:Class	
GO:0001051	biolink:NamedThing	plastid single-subunit type RNA polymerase binding	Binding to a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.	got7fsn_ti							krc	2010-09-23T02:42:57Z						molecular_function											owl:Class	
GO:0004802	biolink:NamedThing	transketolase activity	Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor.	got7fsn_ti	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity|fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity|glycolaldehydetransferase activity|glycoaldehyde transferase activity											Reactome:R-HSA-163751|Reactome:R-HSA-71324|RHEA:10508|EC:2.2.1.1|MetaCyc:1TRANSKETO-RXN|Reactome:R-HSA-71335|Reactome:R-HSA-163741		molecular_function											owl:Class	
GO:0030747	biolink:NamedThing	indolepyruvate C-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate.	got7fsn_ti	indolepyruvic acid methyltransferase activity|S-adenosyl-L-methionine:indolepyruvate C-methyltransferase activity|indolepyruvate methyltransferase activity|indolepyruvate 3-methyltransferase activity|S-adenosyl-L-methionine:(indol-3-yl)pyruvate C-methyltransferase activity											RHEA:12112|EC:2.1.1.47|MetaCyc:INDOLEPYRUVATE-C-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:1990576	biolink:NamedThing	G protein-coupled glucose receptor activity	Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G-protein coupled glucose receptor activity						al	2014-12-08T03:15:12Z						molecular_function											owl:Class	
GO:0120217	biolink:NamedThing	DNA gyrase complex	A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB).	got7fsn_ti	topoisomerase II complex						krc	2019-08-20T18:36:35Z						cellular_component											owl:Class	
GO:0008842	biolink:NamedThing	diphosphate-purine nucleoside kinase activity	Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide.	got7fsn_ti	pyrophosphate-dependent nucleoside kinase activity|diphosphate-dependent nucleoside kinase activity|pyrophosphate-purine nucleoside kinase activity|diphosphate:purine nucleoside phosphotransferase activity											MetaCyc:2.7.1.143-RXN|EC:2.7.1.143		molecular_function											owl:Class	
GO:0034270	biolink:NamedThing	Cvt complex	A protein complex that is involved in the Cvt pathway. In budding yeast, the Cvt complex consists of multimers of preApe1p.	got7fsn_ti	cytoplasm-to-vacuole targeting complex|cytoplasm to vacuole targeting complex													cellular_component											owl:Class	
GO:0010818	biolink:NamedThing	T cell chemotaxis	The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.	got7fsn_ti	T-cell chemotaxis													biological_process											owl:Class	
GO:0098825	biolink:NamedThing	peptidyl-histidine guanylation	The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.	got7fsn_ti												RESID:AA0325		biological_process											owl:Class	
GO:0047066	biolink:NamedThing	phospholipid-hydroperoxide glutathione peroxidase activity	Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione.	got7fsn_ti	peroxidation-inhibiting protein activity|phospholipid hydroperoxide glutathione peroxidase activity|glutathione:lipid-hydroperoxide oxidoreductase activity|peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)|PHGPX|hydroperoxide glutathione peroxidase activity											MetaCyc:1.11.1.12-RXN|RHEA:19057|Reactome:R-HSA-9018895|EC:1.11.1.12|Reactome:R-HSA-9020271|Reactome:R-HSA-9018868|Reactome:R-HSA-9020273		molecular_function											owl:Class	
GO:0018489	biolink:NamedThing	vanillate monooxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+).	got7fsn_ti	vanillate demethylase (aerobic) activity|4-hydroxy-3-methoxybenzoate demethylase activity|vanillate:oxygen oxidoreductase (demethylating)|vanillate demethylase activity				Note that this was EC:1.2.3.12.							EC:1.14.13.82|MetaCyc:RXN-10891|KEGG_REACTION:R05274|UM-BBD_reactionID:r0146|RHEA:13021|MetaCyc:RXN-2		molecular_function											owl:Class	
GO:0045961	biolink:NamedThing	negative regulation of development, heterochronic	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.	got7fsn_ti	inhibition of development, heterochronic|down regulation of development, heterochronic|down-regulation of development, heterochronic|downregulation of development, heterochronic													biological_process											owl:Class	
GO:0090193	biolink:NamedThing	positive regulation of glomerulus development	Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.	got7fsn_ti							tb	2009-12-18T11:17:13Z						biological_process											owl:Class	
GO:0047332	biolink:NamedThing	diphosphate-serine phosphotransferase activity	Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H(+) + phosphate.	got7fsn_ti	pyrophosphate-L-serine phosphotransferase activity|pyrophosphate--serine phosphotransferase activity|diphosphate:L-serine O-phosphotransferase activity											KEGG_REACTION:R00584|MetaCyc:2.7.1.80-RXN|EC:2.7.1.80|RHEA:23764		molecular_function											owl:Class	
GO:0018678	biolink:NamedThing	4-hydroxybenzoate 1-hydroxylase activity	Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2.	got7fsn_ti	4-hydroxybenzoate 1-monooxygenase activity|4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)											MetaCyc:1.14.13.64-RXN|UM-BBD_reactionID:r0752|EC:1.14.13.64		molecular_function											owl:Class	
GO:0106136	biolink:NamedThing	lectin-induced modified bacterial internalization	The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	LIMBI						hjd	2018-08-09T17:27:18Z						biological_process											owl:Class	
GO:0051696	biolink:NamedThing	pointed-end actin filament uncapping	The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.	got7fsn_ti	minus-end actin filament uncapping|pointed-end F-actin uncapping|pointed end F-actin uncapping|minus end F-actin uncapping|minus-end F-actin uncapping|pointed end actin filament uncapping|minus end actin filament uncapping													biological_process											owl:Class	
GO:1990017	biolink:NamedThing	somatic portion of tanycyte	Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.	got7fsn_ti	somatic portion						pr	2012-12-19T15:19:25Z				NIF_Subcellular:sao401910342		cellular_component											owl:Class	
GO:0070505	biolink:NamedThing	pollen coat	A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma.	got7fsn_ti	tryphine|pollenkitt													cellular_component											owl:Class	
GO:0044344	biolink:NamedThing	cellular response to fibroblast growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.	got7fsn_ti	cellular response to FGF stimulus						jl	2010-08-25T02:00:51Z						biological_process											owl:Class	
GO:0004809	biolink:NamedThing	tRNA (guanine-N2-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing guanine = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine.	got7fsn_ti	transfer ribonucleate guanine N2-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-N2-)-methyltransferase activity|tRNA(guanine-26,N(2)-N(2)) methyltransferase activity|N2,N2-dimethylguanine tRNA methyltransferase activity|N(2),N(2)-dimethylguanine tRNA methyltransferase activity|tRNA(m(2,2)G26)dimethyltransferase activity|tRNA(guanine-26,N2-N2) methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-2-N-)-methyltransferase activity|tRNA 2,2-dimethylguanosine-26 methyltransferase activity|transfer ribonucleate guanine 2-methyltransferase activity|transfer RNA guanine 2-methyltransferase activity|guanine-N2-methylase activity											Reactome:R-HSA-6786501|Reactome:R-HSA-6782416		molecular_function											owl:Class	
GO:0045098	biolink:NamedThing	type III intermediate filament	A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments.	got7fsn_ti	glial fibrillary acidic protein|peripherin|desmin|type III intermediate filament associated protein|vimentin													cellular_component											owl:Class	
GO:0061530	biolink:NamedThing	aspartate secretion, neurotransmission	The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-21T15:50:10Z						biological_process											owl:Class	
GO:0061528	biolink:NamedThing	aspartate secretion	The regulated release of aspartate by a cell.	got7fsn_ti							dph	2013-06-21T15:45:37Z						biological_process											owl:Class	
GO:0050215	biolink:NamedThing	propanediol dehydratase activity	Catalysis of the reaction: propane-1,2-diol = H(2)O + propanal.	got7fsn_ti	propane-1,2-diol hydro-lyase activity|propanediol dehydrase activity|diol dehydratase activity|diol dehydrase activity|adenosylcobalamin-dependent diol dehydratase activity|1,2-propanediol dehydratase activity|propane-1,2-diol hydro-lyase (propanal-forming)|DL-1,2-propanediol hydro-lyase activity|meso-2,3-butanediol dehydrase activity|dioldehydratase activity|coenzyme B12-dependent diol dehydrase activity											RHEA:14569|KEGG_REACTION:R02376|EC:4.2.1.28|MetaCyc:PROPANEDIOL-DEHYDRATASE-RXN		molecular_function											owl:Class	
GO:0052677	biolink:NamedThing	D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity	Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+.	got7fsn_ti	NADP+-dependent D-arabinitol dehydrogenase activity|ARD1p|D-arabinitol dehydrogenase 1 activity|D-arabinitol:NADP+ dehydrogenase activity						ai	2011-04-12T02:33:43Z				RHEA:21276|MetaCyc:RXN-7971|KEGG_REACTION:R07143		molecular_function											owl:Class	
GO:1990103	biolink:NamedThing	DnaA-HU complex	A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC.	got7fsn_ti	DnaA-HU-DNA complex						bhm	2013-05-14T12:36:39Z						cellular_component											owl:Class	
GO:0070694	biolink:NamedThing	deoxyribonucleoside 5'-monophosphate N-glycosidase activity	Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base.	got7fsn_ti	deoxynucleoside 5'-monophosphate N-glycosidase activity						mah	2009-06-04T03:06:57Z				Reactome:R-HSA-8953339		molecular_function											owl:Class	
GO:0031718	biolink:NamedThing	type 1 cannabinoid receptor binding	Binding to a type 1 cannabinoid receptor.	got7fsn_ti	type 1 cannabinoid receptor ligand													molecular_function											owl:Class	
GO:0034355	biolink:NamedThing	NAD salvage	Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).	got7fsn_ti	NAD salvage pathway													biological_process											owl:Class	
GO:0042140	biolink:NamedThing	late meiotic recombination nodule assembly	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over.	got7fsn_ti														biological_process											owl:Class	
GO:0007146	biolink:NamedThing	meiotic recombination nodule assembly	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes.	got7fsn_ti														biological_process											owl:Class	
GO:0102500	biolink:NamedThing	beta-maltose 4-alpha-glucanotransferase activity	Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose.	got7fsn_ti												MetaCyc:RXN-14354|EC:2.4.1.25		molecular_function											owl:Class	
GO:1990971	biolink:NamedThing	EMILIN complex	Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures.	got7fsn_ti	EMILIN-1 complex|Elastic microfibrillar interface 1 complex|Elastic microfibrillar interface 2 complex|EMILIN-2 complex				An example of this is EMILIN-1 in human (Q9Y6C2) in PMID:10821830 (inferred from direct assay).		bhm	2016-06-21T14:41:18Z						cellular_component											owl:Class	
GO:0030197	biolink:NamedThing	extracellular matrix constituent, lubricant activity	Functions as a lubricant for an extracellular matrix, such as a mucous membrane.	got7fsn_ti	core matrisome|core extracellular matrix				Extracellular matrix mucin proteins may be annotated to this term. PMID:14711375, PMID:18601586									molecular_function											owl:Class	
GO:0031527	biolink:NamedThing	filopodium membrane	The portion of the plasma membrane surrounding a filopodium.	got7fsn_ti														cellular_component											owl:Class	
GO:0071080	biolink:NamedThing	alpha3-beta1 integrin-basigin complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.	got7fsn_ti	ITGA3-ITGB1-BSG complex						mah	2009-11-06T04:43:26Z						cellular_component											owl:Class	
GO:0039662	biolink:NamedThing	host cell outer membrane	A lipid bilayer that forms the outermost layer of the cell envelope, occurring in a host cell.	got7fsn_ti	outer membrane of host cell|host cell envelope outer membrane						bf	2013-08-25T10:48:41Z						cellular_component											owl:Class	
GO:0031443	biolink:NamedThing	fast-twitch skeletal muscle fiber contraction	A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.	got7fsn_ti	fast-twitch skeletal myofibre contraction|fast-twitch skeletal myofiber contraction|fast-twitch skeletal muscle fibre contraction|fast-twitch skeletal fiber contraction|fast-twitch skeletal fibre contraction													biological_process											owl:Class	
GO:0014721	biolink:NamedThing	twitch skeletal muscle contraction	A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.	got7fsn_ti														biological_process											owl:Class	
GO:0060424	biolink:NamedThing	lung field specification	The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop.	got7fsn_ti	lung specification													biological_process											owl:Class	
GO:0102495	biolink:NamedThing	GA5 3beta-hydroxylase activity	Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A3 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-14318		molecular_function											owl:Class	
GO:0019915	biolink:NamedThing	lipid storage	The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.	got7fsn_ti	storage of lipids|retention of lipids|lipid retention|sequestration of lipids|sequestration of lipid|sequestering of lipids|lipid sequestering|lipid sequestration													biological_process											owl:Class	
GO:0035494	biolink:NamedThing	SNARE complex disassembly	The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	got7fsn_ti							bf	2010-04-26T02:54:17Z						biological_process											owl:Class	
GO:0060887	biolink:NamedThing	limb epidermis development	The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.	got7fsn_ti							dph	2009-08-13T12:39:39Z						biological_process											owl:Class	
GO:0052336	biolink:NamedThing	modification by host of symbiont cell wall	The process in which an organism effects a change in the structure or function of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	metabolism of symbiont cell wall by organism													biological_process											owl:Class	
GO:0006644	biolink:NamedThing	phospholipid metabolic process	The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.	got7fsn_ti	phospholipid metabolism													biological_process											owl:Class	
GO:0046193	biolink:NamedThing	anaerobic phenol-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.	got7fsn_ti	anaerobic phenol-containing compound catabolism|anaerobic phenol-containing compound breakdown|anaerobic phenol-containing compound degradation													biological_process											owl:Class	
GO:1901038	biolink:NamedThing	cyanidin 3-O-glucoside metabolic process	The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside.	got7fsn_ti	cyanidin 3-O-beta-D-glucoside metabolic process|cyanidin 3-O-beta-D-glucoside metabolism						tb	2012-06-22T12:16:26Z						biological_process											owl:Class	
GO:0034544	biolink:NamedThing	trans-ACOHDA hydrolase activity	Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3.	got7fsn_ti												UM-BBD_reactionID:r0810|EC:3.5.99.-		molecular_function											owl:Class	
GO:0102897	biolink:NamedThing	abietadienal hydroxylase activity	Catalysis of the reaction: abietal + NADPH + O2 <=> abietate + NADP + H2O.	got7fsn_ti												RHEA:56928|MetaCyc:RXN-8510		molecular_function											owl:Class	
GO:0044605	biolink:NamedThing	phosphocholine transferase activity	Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate.	got7fsn_ti							jl	2012-05-24T04:44:25Z						molecular_function											owl:Class	
GO:0060276	biolink:NamedThing	maintenance of stationary phase in response to toxin	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment.	got7fsn_ti														biological_process											owl:Class	
GO:0060274	biolink:NamedThing	maintenance of stationary phase	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment.	got7fsn_ti														biological_process											owl:Class	
GO:0047579	biolink:NamedThing	4-hydroxymandelate oxidase activity	Catalysis of the reaction: (S)-4-hydroxymandelate + H(+) + O(2) = 4-hydroxybenzaldehyde + CO(2) + H(2)O(2).	got7fsn_ti	(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase activity|L-4-hydroxymandelate oxidase (decarboxylating)											MetaCyc:4-HYDROXYMANDELATE-OXIDASE-RXN|RHEA:15833|KEGG_REACTION:R02673|EC:1.1.3.19		molecular_function											owl:Class	
GO:0018716	biolink:NamedThing	1-phenanthrol glycosyltransferase activity	Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O.	got7fsn_ti												UM-BBD_reactionID:r0525		molecular_function											owl:Class	
GO:0033873	biolink:NamedThing	petromyzonol sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+).	got7fsn_ti	PZ-SULT|3'-phosphoadenylyl-sulfate:5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol sulfotransferase activity											EC:2.8.2.31|MetaCyc:2.8.2.31-RXN|RHEA:16997|KEGG_REACTION:R07797		molecular_function											owl:Class	
GO:0010357	biolink:NamedThing	homogentisate solanesyltransferase activity	Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0055041	biolink:NamedThing	cyclopentanol dehydrogenase activity	Catalysis of the reaction: cyclopentanol + NAD(+) = cyclopentanone + H(+) + NADH.	got7fsn_ti	cyclopentanol:NADP+ oxidoreductase activity|cyclopentanol:NAD+ oxidoreductase activity											MetaCyc:CYCLOPENTANOL-DEHYDROGENASE-RXN|KEGG_REACTION:R02553|EC:1.1.1.163|RHEA:11728		molecular_function											owl:Class	
GO:0120280	biolink:NamedThing	ciliary pro-basal body	The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium.	got7fsn_ti	pro-basal body|pro-centriole|flagellar pro-basal body|probasal body|flagellar probasal body	https://github.com/geneontology/go-ontology/issues/14963			Pro-basal bodies are distinct from basal bodies as they are not at the base of a cilium and are not capable of nucleating a cilium. While immature, they contain some structures in common with the mature basal body and also may contain proteins unique to the immature state. Note that cilia and eukaryotic flagella are deemed to be equivalent. In many eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component. In other eukaryotic cells, centrioles are not involved in cell division but only in cilium assembly, which is thought to be the ancestral role of the centriole/basal body.		krc	2020-10-29T22:54:44Z						cellular_component											owl:Class	
GO:0008740	biolink:NamedThing	L-rhamnose isomerase activity	Catalysis of the reaction: L-rhamnose = L-rhamnulose.	got7fsn_ti	L-rhamnose aldose-ketose-isomerase activity|rhamnose isomerase activity|L-rhamnose ketol-isomerase activity											EC:5.3.1.14|RHEA:23160|KEGG_REACTION:R02437|MetaCyc:RHAMNISOM-RXN		molecular_function											owl:Class	
GO:0009558	biolink:NamedThing	embryo sac cellularization	The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana.	got7fsn_ti	megagametophyte cellularization|female gametophyte cellularization|cellularization of the embryo sac										GO:0009797			biological_process											owl:Class	
GO:0160001	biolink:NamedThing	extrasynaptic signaling via GABA	Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid.	got7fsn_ti							rl	2021-02-26T23:08:15Z						biological_process											owl:Class	
GO:0007214	biolink:NamedThing	gamma-aminobutyric acid signaling pathway	The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.	got7fsn_ti	4-aminobutanoate signaling pathway|4-aminobutyrate signaling pathway|gamma-aminobutyric acid signalling pathway|GABA signalling pathway|4-aminobutanoate signalling pathway|4-aminobutyrate signalling pathway|GABA signaling pathway													biological_process											owl:Class	
GO:0102350	biolink:NamedThing	trans-cerot-2-enoyl-CoA reductase activity	Catalysis of the reaction: hexacosanoyl-CoA(4-) + NADP(3-) <=> trans-2-hexacosenoyl-CoA + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13309		molecular_function											owl:Class	
GO:0071283	biolink:NamedThing	cellular response to iron(III) ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.	got7fsn_ti	cellular response to iron(III)						mah	2009-12-10T03:58:00Z						biological_process											owl:Class	
GO:0010998	biolink:NamedThing	regulation of translational initiation by eIF2 alpha phosphorylation	Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.	got7fsn_ti	regulation of translational initiation by eIF2 alpha phosphorylation in response to stress|eIF2 alpha phosphorylation in response to stress				Consider also annotating to 'eukaryotic translation initiation factor 2alpha kinase activity ; GO:0004694'.		tb	2009-06-10T11:27:47Z						biological_process											owl:Class	
GO:0140706	biolink:NamedThing	protein-containing complex localization to centriolar satellite	A protein-containing complex localization by which the complex is transported to, or maintained in, the centriolar satellite.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22020					pg	2021-09-01T05:59:13Z						biological_process											owl:Class	
GO:0097248	biolink:NamedThing	maintenance of protein location in cell cortex of cell tip	A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell.	got7fsn_ti							pr	2012-02-20T04:27:31Z						biological_process											owl:Class	
GO:0032065	biolink:NamedThing	maintenance of protein location in cell cortex	A process in which a protein or protein complex is maintained in a specific location in the cell cortex.	got7fsn_ti	maintenance of protein location in cell cortex|cortical protein anchoring													biological_process											owl:Class	
GO:0030251	biolink:NamedThing	guanylate cyclase inhibitor activity	Stops, prevents or reduces the activity of guanylate cyclase.	got7fsn_ti														molecular_function											owl:Class	
GO:0051367	biolink:NamedThing	peptidyl-serine decanoylation	The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.	got7fsn_ti												RESID:AA0385		biological_process											owl:Class	
GO:0000102	biolink:NamedThing	L-methionine secondary active transmembrane transporter activity	Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	L-methionine porter activity													molecular_function											owl:Class	
GO:0048648	biolink:NamedThing	caste determination	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.	got7fsn_ti														biological_process											owl:Class	
GO:0060684	biolink:NamedThing	epithelial-mesenchymal cell signaling	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.	got7fsn_ti	epithelial-mesenchymal cell signalling						dph	2009-06-03T06:36:46Z						biological_process											owl:Class	
GO:0080162	biolink:NamedThing	intracellular auxin transport	The directed movement of auxins within a cell. Auxins are a group of plant hormones that regulates aspects of plant growth.	got7fsn_ti							dhl	2010-09-23T03:46:29Z						biological_process											owl:Class	
GO:0097154	biolink:NamedThing	GABAergic neuron differentiation	The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.	got7fsn_ti							pr	2011-09-14T09:39:11Z						biological_process											owl:Class	
GO:0033255	biolink:NamedThing	SAS acetyltransferase complex	A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.	got7fsn_ti	SAS-I complex													cellular_component											owl:Class	
GO:0044342	biolink:NamedThing	type B pancreatic cell proliferation	The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin.	got7fsn_ti	pancreatic beta cell proliferation|pancreatic B cell proliferation						jl	2010-08-25T01:44:51Z						biological_process											owl:Class	
GO:0050107	biolink:NamedThing	monoterpenol O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester.	got7fsn_ti	acetyl-CoA:monoterpenol O-acetyltransferase activity|menthol transacetylase activity											MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.69		molecular_function											owl:Class	
GO:0034431	biolink:NamedThing	bis(5'-adenosyl)-hexaphosphatase activity	Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.	got7fsn_ti	diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity|AP6A hydrolase activity|AP-6-A hydrolase activity|AP(6)A hydrolase activity											RHEA:32047		molecular_function											owl:Class	
GO:0036105	biolink:NamedThing	peroxisome membrane class-1 targeting sequence binding	Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.	got7fsn_ti	class 1 mPTS binding|PEX19-dependent mPTS binding				Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence.		bf	2012-01-27T02:02:22Z						molecular_function											owl:Class	
GO:0033328	biolink:NamedThing	peroxisome membrane targeting sequence binding	Binding to a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane.	got7fsn_ti	peroxisomal membrane protein (PMP) targeting signal (mPTS) binding|PMP targeting signal (mPTS) binding|PMP targeting signal binding|mPTS binding													molecular_function											owl:Class	
GO:0047946	biolink:NamedThing	glutamine N-acyltransferase activity	Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine.	got7fsn_ti	acyl-CoA:L-glutamine N-acyltransferase activity											EC:2.3.1.68|RHEA:18469|MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0004848	biolink:NamedThing	ureidoglycolate hydrolase activity	Catalysis of the reaction: (S)-ureidoglycolate + H(2)O + 2 H(+) = CO(2) + glyoxylate + 2 NH(4)(+).	got7fsn_ti	(S)-ureidoglycolate amidohydrolase (decarboxylating)				Take care to annotate to the reaction, not simply the enzyme name. The name "ureidoglycolate hydrolase" has variously been used to refer to two distinctly different enzymes. Both enzymes act on ureidoglycolate and produce glyoxylate, but the mechanism and reaction products are different. The "ureidoglycolate hydrolase" listed in the Enzyme commission (EC) is a ureidoglycolate amidohydrolase, releasing ammonia, (EC:3.5.3.19, GO:0004848). The "ureidoglycolate hydrolase" characterized in PMID:3915539 (published prior to the EC designation of EC:3.5.3.19) is a ureidoglycolate lyase, releasing urea (EC:4.3.2.3, GO:0050385). The inappropriate labelling of ureidoglycolate lyase as EC:3.5.3.19 has caused much confusion in the literature (see PMID:24107613). Take care to correctly annotate based on the reaction products, rather than name.							MetaCyc:UREIDOGLYCOLATE-HYDROLASE-RXN|EC:3.5.3.19|KEGG_REACTION:R00469|RHEA:19809		molecular_function											owl:Class	
GO:0031771	biolink:NamedThing	type 1 hypocretin receptor binding	Binding to a type 1 hypocretin receptor.	got7fsn_ti	type 1 hypocretin receptor ligand|type 1 orexin receptor binding													molecular_function											owl:Class	
GO:0052009	biolink:NamedThing	disruption by symbiont of host cell wall	A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	disassembly by symbiont of host cell wall													biological_process											owl:Class	
GO:0099642	biolink:NamedThing	retrograde axonal protein transport	The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons.	got7fsn_ti	retrograde axon cargo transport													biological_process											owl:Class	
GO:0008694	biolink:NamedThing	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2.	got7fsn_ti	3-polyprenyl-4-hydroxybenzoate carboxy-lyase activity|UbiX|3-octaprenyl-4-hydroxybenzoate decarboxylase activity|polyprenyl p-hydroxybenzoate decarboxylase activity|UbiD|PPHB decarboxylase activity|3-polyprenyl 4-hydroxybenzoate decarboxylase activity										GO:0019167	RHEA:27778|EC:4.1.1.98|MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN		molecular_function											owl:Class	
GO:0060084	biolink:NamedThing	synaptic transmission involved in micturition	The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.	got7fsn_ti	synaptic transmission involved in urination													biological_process											owl:Class	
GO:0072065	biolink:NamedThing	long descending thin limb bend development	The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.	got7fsn_ti							mah	2010-01-25T04:13:38Z						biological_process											owl:Class	
GO:0050509	biolink:NamedThing	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.	got7fsn_ti	UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity|N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity|N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity|heparan glucuronyltransferase II activity											Reactome:R-HSA-9036285|MetaCyc:2.4.1.225-RXN|Reactome:R-HSA-3656257|Reactome:R-HSA-2076392|Reactome:R-HSA-9036289|Reactome:R-HSA-2022856|Reactome:R-HSA-3656267|RHEA:20908|EC:2.4.1.225		molecular_function											owl:Class	
GO:0021573	biolink:NamedThing	rhombomere 7 development	The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0016612	biolink:NamedThing	molybdenum-iron nitrogenase complex	An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.	got7fsn_ti	molybdenum-iron nitrogenase activity													cellular_component											owl:Class	
GO:0060529	biolink:NamedThing	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.	got7fsn_ti														biological_process											owl:Class	
GO:0002067	biolink:NamedThing	glandular epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.	got7fsn_ti														biological_process											owl:Class	
GO:1990408	biolink:NamedThing	calcitonin gene-related peptide receptor signaling pathway	A series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.	got7fsn_ti	calcitonin-gene-related peptide receptor signaling pathway|CGRP receptor signaling pathway|calcitonin-gene-related polypeptide receptor signaling pathway				An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.		bhm	2014-07-02T14:32:37Z						biological_process											owl:Class	
GO:0106324	biolink:NamedThing	(S)-limonene 1,2-monooxygenase NADH activity	Catalysis of the reaction: (4S)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4S)-limonene-1,2-epoxide.	got7fsn_ti							hjd	2020-09-23T15:35:58Z				RHEA:26089		molecular_function											owl:Class	
GO:0052601	biolink:NamedThing	(S)-limonene 1,2-monooxygenase activity	Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide.	got7fsn_ti	(S)-limonene,NAD(P)H:oxygen oxidoreductase activity|(-)-limonene 1,2-monooxygenase activity|(-)-limonene,NAD(P)H:oxygen oxidoreductase activity											KEGG_REACTION:R09389|KEGG_REACTION:R09385|EC:1.14.13.107|MetaCyc:RXN-9409		molecular_function											owl:Class	
GO:0035128	biolink:NamedThing	post-embryonic forelimb morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0045842	biolink:NamedThing	positive regulation of mitotic metaphase/anaphase transition	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.	got7fsn_ti	upregulation of mitotic metaphase/anaphase transition|up regulation of mitotic metaphase/anaphase transition|activation of mitotic metaphase/anaphase transition|stimulation of mitotic metaphase/anaphase transition|up-regulation of mitotic metaphase/anaphase transition													biological_process											owl:Class	
GO:1901970	biolink:NamedThing	positive regulation of mitotic sister chromatid separation	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.	got7fsn_ti	upregulation of sister chromatid separation during mitosis|upregulation of mitotic sister chromatid separation|up regulation of mitotic sister chromatid resolution|activation of sister chromatid separation during mitosis|positive regulation of chromosome separation during mitosis|upregulation of mitotic sister chromatid resolution|up-regulation of sister chromatid separation during mitosis|positive regulation of sister chromatid separation during mitosis|upregulation of mitotic chromosome separation|up regulation of mitotic chromosome separation|up regulation of sister chromatid separation during mitosis|up regulation of mitotic sister chromatid separation|activation of mitotic chromosome separation|positive regulation of mitotic sister chromatid resolution|up-regulation of mitotic chromosome separation|positive regulation of mitotic chromosome separation|up regulation of chromosome separation during mitosis|activation of chromosome separation during mitosis|upregulation of chromosome separation during mitosis|up-regulation of mitotic sister chromatid separation|up-regulation of chromosome separation during mitosis|activation of mitotic sister chromatid separation|up-regulation of mitotic sister chromatid resolution|activation of mitotic sister chromatid resolution						al	2013-02-22T19:06:19Z						biological_process											owl:Class	
GO:0002367	biolink:NamedThing	cytokine production involved in immune response	The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	cytokine biosynthetic process involved in immune response|cytokine production during immune response|cytokine secretion during immune response|cytokine secretion involved in immune response				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0002375|GO:0002374			biological_process											owl:Class	
GO:0015314	biolink:NamedThing	aminotriazole:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out).	got7fsn_ti	aminotriazole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0002234	biolink:NamedThing	detection of endoplasmic reticulum overloading	The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.	got7fsn_ti	detection of ER overloading													biological_process											owl:Class	
GO:0018718	biolink:NamedThing	1,2-dihydroxy-phenanthrene glycosyltransferase activity	Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.	got7fsn_ti												UM-BBD_reactionID:r0569		molecular_function											owl:Class	
GO:0036500	biolink:NamedThing	ATF6-mediated unfolded protein response	A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity.	got7fsn_ti	ATF6 signaling in response to endoplasmic reticulum stress|activating transcription factor 6 signaling in unfolded protein response|ATF6 signal transduction pathway|ATF6-beta UPR branch|UPR signaling by ATF6 stress sensor|ATF6 branch of UPR|ATF6-alpha UPR branch|endoplasmic reticulum unfolded protein response; ATF6 signaling						bf	2015-02-05T13:18:58Z						biological_process											owl:Class	
GO:0050161	biolink:NamedThing	succinyl-CoA:oxalate CoA-transferase	Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate.	got7fsn_ti	succinyl-beta-ketoacyl-CoA transferase activity|succinyl-CoA:oxalate CoA-transferase activity|oxalate coenzyme A-transferase activity|oxalate CoA-transferase activity											MetaCyc:OXALATE-COA-TRANSFERASE-RXN|KEGG_REACTION:R01559|RHEA:23588|EC:2.8.3.2		molecular_function											owl:Class	
GO:0015990	biolink:NamedThing	electron transport coupled proton transport	The transport of protons against an electrochemical gradient, using energy from electron transport.	got7fsn_ti														biological_process											owl:Class	
GO:0003301	biolink:NamedThing	physiological cardiac muscle hypertrophy	The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.	got7fsn_ti							dph	2009-10-22T10:38:10Z						biological_process											owl:Class	
GO:0008409	biolink:NamedThing	5'-3' exonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end.	got7fsn_ti												Reactome:R-HSA-5358619|Reactome:R-HSA-5358599		molecular_function											owl:Class	
GO:0061538	biolink:NamedThing	histamine secretion, neurotransmission	The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-21T16:21:21Z						biological_process											owl:Class	
GO:0090076	biolink:NamedThing	relaxation of skeletal muscle	A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.	got7fsn_ti							tb	2009-09-11T11:44:32Z						biological_process											owl:Class	
GO:0006621	biolink:NamedThing	protein retention in ER lumen	The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.	got7fsn_ti	maintenance of protein location in ER lumen													biological_process											owl:Class	
GO:1990277	biolink:NamedThing	parasexual conjugation with cellular fusion	A conjugation process that results in the union of cellular and genetic information from compatible mating types, without the formation of zygotes. An example of this process is found in Candida albicans.	got7fsn_ti	mating						pr	2014-01-28T10:30:20Z						biological_process											owl:Class	
GO:0022819	biolink:NamedThing	potassium ion uniporter activity	Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.	got7fsn_ti														molecular_function											owl:Class	
GO:0034573	biolink:NamedThing	didemethylisoproturon amidohydrolase activity	Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline.	got7fsn_ti												UM-BBD_reactionID:r0898		molecular_function											owl:Class	
GO:0103061	biolink:NamedThing	trans-methoxy-C60-meroacyl-AMP ligase activity	Catalysis of the reaction: ATP(4-) + H2O + a trans-methoxy-C60-meroacyl-[acp] <=> diphosphoric acid + a trans-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN1G-4141		molecular_function											owl:Class	
GO:0050003	biolink:NamedThing	deoxycytidylate C-methyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate.	got7fsn_ti	5,10-methylenetetrahydrofolate:dCMP C-methyltransferase activity|dCMP methyltransferase activity|deoxycytidylate methyltransferase activity											RHEA:11568|EC:2.1.1.54|MetaCyc:DEOXYCYTIDYLATE-C-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01670		molecular_function											owl:Class	
GO:0003829	biolink:NamedThing	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R.	got7fsn_ti	uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity|core 2 acetylglucosaminyltransferase activity|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity|beta(6)-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase activity|core 6-beta-GlcNAc-transferase A|beta6-N-acetylglucosaminyltransferase activity	https://github.com/geneontology/go-ontology/issues/21793										EC:2.4.1.102|Reactome:R-HSA-914012|Reactome:R-HSA-914018|MetaCyc:2.4.1.102-RXN|RHEA:18705		molecular_function											owl:Class	
GO:0033752	biolink:NamedThing	acetylacetone-cleaving enzyme activity	Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal.	got7fsn_ti	acetylacetone-cleaving enzyme|acetylacetone:oxygen oxidoreductase activity|acetylacetone dioxygenase activity|Dke1|diketone cleaving dioxygenase activity|diketone cleaving enzyme											EC:1.13.11.50|RHEA:12877		molecular_function											owl:Class	
GO:0044302	biolink:NamedThing	dentate gyrus mossy fiber	Distinctive, unmyelinated axons produced by granule cells.	got7fsn_ti	dentate gyrus mossy fibre|granule cell axon						jl	2010-02-05T11:23:55Z				NIF_Subcellular:nlx_subcell_20090601		cellular_component											owl:Class	
GO:0045550	biolink:NamedThing	geranylgeranyl reductase activity	Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group.	got7fsn_ti														molecular_function											owl:Class	
GO:0046402	biolink:NamedThing	O antigen metabolic process	The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.	got7fsn_ti	O antigen metabolism													biological_process											owl:Class	
GO:0102127	biolink:NamedThing	8-oxoguanine deaminase activity	Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O <=> 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium.	got7fsn_ti												RHEA:32067|MetaCyc:RXN-11455|EC:3.5.4.32		molecular_function											owl:Class	
GO:0035790	biolink:NamedThing	platelet-derived growth factor receptor-alpha signaling pathway	A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	PDGF receptor-alpha signaling pathway|platelet-derived growth factor receptor-alpha signalling pathway|PDGFR-alpha signaling pathway|alphaPDGF receptor signaling pathway						bf	2011-04-06T10:55:16Z						biological_process											owl:Class	
GO:0016605	biolink:NamedThing	PML body	A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	got7fsn_ti	nuclear dot|PML nuclear body|PML NB|ND10													cellular_component											owl:Class	
GO:0030733	biolink:NamedThing	fatty acid O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester.	got7fsn_ti	S-adenosyl-L-methionine:fatty-acid O-methyltransferase activity|fatty-acid O-methyltransferase activity|fatty acid methyltransferase activity											MetaCyc:FATTY-ACID-O-METHYLTRANSFERASE-RXN|EC:2.1.1.15|RHEA:23012		molecular_function											owl:Class	
GO:1900598	biolink:NamedThing	demethylkotanin catabolic process	The chemical reactions and pathways resulting in the breakdown of demethylkotanin.	got7fsn_ti	demethylkotanin breakdown|demethylkotanin catabolism|demethylkotanin degradation						di	2012-05-15T06:55:14Z						biological_process											owl:Class	
GO:0102160	biolink:NamedThing	cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate <=> H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-11756|EC:2.4.1.254|RHEA:28258		molecular_function											owl:Class	
GO:0044875	biolink:NamedThing	gamma-glutamyl hercynylcysteine sulfoxide synthase activity	Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 <=> gamma-glutamyl-hercynyl cysteine sulfoxide + H2O.	got7fsn_ti	gamma-glutamyl hercynylcysteine S-oxide synthase|gamma-glutamyl hercynylcysteine sulfoxide synthase	https://github.com/geneontology/go-ontology/issues/11163					jl	2014-12-15T11:44:54Z				EC:1.14.99.50|RHEA:42672		molecular_function											owl:Class	
GO:0010454	biolink:NamedThing	negative regulation of cell fate commitment	Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.	got7fsn_ti														biological_process											owl:Class	
GO:0106100	biolink:NamedThing	beta-pinacene synthase activity	Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene.	got7fsn_ti							hjd	2018-02-15T16:51:59Z						molecular_function											owl:Class	
GO:0035521	biolink:NamedThing	monoubiquitinated histone deubiquitination	The removal of the ubiquitin group from a monoubiquitinated histone protein.	got7fsn_ti	monoubiquitinated histone deubiquitinylation|monoubiquitinated histone deubiquitylation						bf	2010-05-04T04:32:04Z						biological_process											owl:Class	
GO:0102467	biolink:NamedThing	scutellarein 7-O-glucuronosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate + scutellarein <=> UDP( + scutellarin + H+.	got7fsn_ti												RHEA:28318|EC:2.4.1.253|MetaCyc:RXN-14058		molecular_function											owl:Class	
GO:0010176	biolink:NamedThing	homogentisate phytyltransferase activity	Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol.	got7fsn_ti												MetaCyc:RXN-2541|KEGG_REACTION:R07500|RHEA:37975		molecular_function											owl:Class	
GO:0018671	biolink:NamedThing	4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity	Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O.	got7fsn_ti	4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)|4-hydroxybenzoate 3-hydroxylase activity|4-hydroxybenzoate-3-hydroxylase activity|4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate))											EC:1.14.13.33|MetaCyc:1.14.13.33-RXN		molecular_function											owl:Class	
GO:0070738	biolink:NamedThing	tubulin-glycine ligase activity	Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.	got7fsn_ti	tubulin glycylase activity						mah	2009-06-19T02:02:01Z						molecular_function											owl:Class	
GO:0042167	biolink:NamedThing	heme catabolic process	The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.	got7fsn_ti	haem catabolic process|heme breakdown|heme catabolism|haem catabolism|heme degradation													biological_process											owl:Class	
GO:1990640	biolink:NamedThing	inositol-2,4,5-triphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate.	got7fsn_ti							al	2015-02-11T18:20:40Z						molecular_function											owl:Class	
GO:0004843	biolink:NamedThing	thiol-dependent deubiquitinase	Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.	got7fsn_ti	deubiquitinase|deubiquitinating enzyme|ubiquitin hydrolase activity|UCH2|deubiquitylase|ubiquitinyl hydrolase 1 activity|thiol-dependent ubiquitinyl hydrolase activity|ubiquitinyl hydrolase activity|ubiquitin-specific protease activity|UBP|thiol-dependent ubiquitin-specific protease activity|deubiquitinase activity|ubiquitin C-terminal hydrolase	https://github.com/geneontology/go-ontology/issues/19723									GO:0036459	Reactome:R-HSA-5690157|Reactome:R-HSA-5696945|Reactome:R-HSA-5690196|Reactome:R-HSA-870437|Reactome:R-HSA-5689950|EC:3.4.19.12|Reactome:R-HSA-6807206|Reactome:R-HSA-6807118|Reactome:R-HSA-6781764|Reactome:R-HSA-5690152|Reactome:R-HSA-8862184|Reactome:R-HSA-5696872|Reactome:R-HSA-3640872|Reactome:R-HSA-5696968|Reactome:R-HSA-5690159|Reactome:R-HSA-9653514|Reactome:R-HSA-5690790|Reactome:R-HSA-8865182|Reactome:R-HSA-5696605|Reactome:R-HSA-9033491|Reactome:R-HSA-5655466|Reactome:R-HSA-8875443|Reactome:R-HSA-5696914|Reactome:R-HSA-5696564|Reactome:R-HSA-5696465|Reactome:R-HSA-6783177|Reactome:R-HSA-2179291|Reactome:R-HSA-5688797|Reactome:R-HSA-8853514|Reactome:R-HSA-6781779|Reactome:R-HSA-5690759|Reactome:R-HSA-6781814|Reactome:R-HSA-5689972|Reactome:R-HSA-8869456|Reactome:R-HSA-5696600|Reactome:R-HSA-5696958|Reactome:R-HSA-8873946|Reactome:R-HSA-5689973|Reactome:R-HSA-9033478|Reactome:R-HSA-5688837|Reactome:R-HSA-6786171|Reactome:R-HSA-5697009|Reactome:R-HSA-6782628|Reactome:R-HSA-6782820|Reactome:R-HSA-6782106|Reactome:R-HSA-1358795|Reactome:R-HSA-3215310|Reactome:R-HSA-8986083|Reactome:R-HSA-8853515|Reactome:R-HSA-5690319|Reactome:R-HSA-5696947|Reactome:R-HSA-4641236|Reactome:R-HSA-3215295|Reactome:R-HSA-5696534|Reactome:R-HSA-6781897|Reactome:R-HSA-6782069|Reactome:R-HSA-5696627|Reactome:R-HSA-8853529|Reactome:R-HSA-5690080|Reactome:R-HSA-8853503|Reactome:R-HSA-5696960|Reactome:R-HSA-5653770|Reactome:R-HSA-5691381|Reactome:R-HSA-5696997		molecular_function											owl:Class	
GO:0000088	biolink:NamedThing	mitotic prophase	The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0046015	biolink:NamedThing	regulation of transcription by glucose	Any process involving glucose that modulates the frequency, rate or extent or transcription.	got7fsn_ti														biological_process											owl:Class	
GO:0002354	biolink:NamedThing	central B cell negative selection	Any process leading to negative selection of B cells in the bone marrow.	got7fsn_ti	central B lymphocyte negative selection|central B-lymphocyte negative selection|central B-cell negative selection													biological_process											owl:Class	
GO:0002340	biolink:NamedThing	central B cell selection	Any B cell selection process that occurs in the bone marrow.	got7fsn_ti	central B lymphocyte selection|central B-cell selection|central B-lymphocyte selection													biological_process											owl:Class	
GO:0050014	biolink:NamedThing	ketotetrose-phosphate aldolase activity	Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate.	got7fsn_ti	erythrulose-1-phosphate formaldehyde-lyase activity|erythrose-1-phosphate synthase activity|phosphoketotetrose aldolase activity|erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming)|erythrulose-1-phosphate synthetase activity											KEGG_REACTION:R01014|MetaCyc:KETOTETROSE-PHOSPHATE-ALDOLASE-RXN|EC:4.1.2.2|RHEA:20932		molecular_function											owl:Class	
GO:0016009	biolink:NamedThing	minor mitochondrial derivative	The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20737												cellular_component											owl:Class	
GO:1990680	biolink:NamedThing	response to melanocyte-stimulating hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates.	got7fsn_ti	response to MSH						sl	2015-03-02T20:49:46Z						biological_process											owl:Class	
GO:0010948	biolink:NamedThing	negative regulation of cell cycle process	Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.	got7fsn_ti							tb	2009-04-27T09:53:22Z						biological_process											owl:Class	
GO:0018483	biolink:NamedThing	6-oxohexanoate dehydrogenase activity	Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+.	got7fsn_ti	6-oxohexanoate:NADP+ oxidoreductase activity											MetaCyc:6-OXOHEXANOATE-OXIDATION-RXN|EC:1.2.1.63|RHEA:13397|UM-BBD_reactionID:r0175		molecular_function											owl:Class	
GO:0051819	biolink:NamedThing	induction by symbiont of tumor or growth in host	The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic.	got7fsn_ti	induction by symbiont in host of tumor, nodule, or growth containing transformed cells|induction of tumor, nodule, or growth in other organism involved in symbiotic interaction|induction of tumor, nodule, or growth containing transformed cells in other organism involved in symbiotic interaction|induction by symbiont in host of tumor, nodule, or growth|induction by symbiont of nodulation, tumor or growth in host|induction of tumor, nodule, or growth in other organism during symbiotic interaction|induction of tumor, nodule, or growth containing transformed cells in other organism during symbiotic interaction										GO:0051820|GO:0044005|GO:0044006			biological_process											owl:Class	
GO:0002525	biolink:NamedThing	acute inflammatory response to non-antigenic stimulus	An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.	got7fsn_ti														biological_process											owl:Class	
GO:0006616	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane, translocation	The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen.	got7fsn_ti	ER translocation|translocation during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, translocation|SRP-dependent cotranslational protein-membrane targeting, translocation													biological_process											owl:Class	
GO:0035232	biolink:NamedThing	germ cell attraction	The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target.	got7fsn_ti														biological_process											owl:Class	
GO:0106077	biolink:NamedThing	histone succinylation	The modification of a histone by the addition of an succinyl group.	got7fsn_ti							hjd	2017-12-15T18:27:16Z						biological_process											owl:Class	
GO:0018335	biolink:NamedThing	protein succinylation	The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue.	got7fsn_ti	protein amino acid succinylation													biological_process											owl:Class	
GO:0030315	biolink:NamedThing	T-tubule	Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.	got7fsn_ti	transverse tubule|triad											Wikipedia:T-tubule		cellular_component											owl:Class	
GO:0033442	biolink:NamedThing	AAC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AAC codon.	got7fsn_ti	asparagine tRNA				Note that in the standard genetic code, AAC codes for asparagine.									molecular_function											owl:Class	
GO:0018644	biolink:NamedThing	toluene 2-monooxygenase activity	Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene.	got7fsn_ti												UM-BBD_enzymeID:e0222|EC:1.14.13.243|MetaCyc:TOLUENE-2-MONOOXYGENASE-RXN|RHEA:20349		molecular_function											owl:Class	
GO:0071064	biolink:NamedThing	alphaE-beta7 integrin-E-cadherin complex	A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.	got7fsn_ti	ITGAE-ITGB7-CDH1 complex						mah	2009-11-03T04:03:37Z						cellular_component											owl:Class	
GO:0071180	biolink:NamedThing	MAML3-RBP-Jkappa-ICN2 complex	A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML3-RBP-Jkappa-Notch2 complex						mah	2009-11-23T02:51:29Z						cellular_component											owl:Class	
GO:0006056	biolink:NamedThing	mannoprotein metabolic process	The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues.	got7fsn_ti	mannoprotein metabolism													biological_process											owl:Class	
GO:0106272	biolink:NamedThing	protein localization to ERGIC	A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).	got7fsn_ti							hjd	2020-07-01T17:04:35Z						biological_process											owl:Class	
GO:0034067	biolink:NamedThing	protein localization to Golgi apparatus	A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.	got7fsn_ti	establishment of protein localization to Golgi apparatus|establishment of protein localisation to Golgi|establishment of protein localization in Golgi|protein targeting to Golgi|protein-Golgi targeting|establishment of protein localization to Golgi|protein localisation in Golgi apparatus|protein localization in Golgi apparatus						mah	2011-02-14T02:26:36Z			GO:0000042|GO:0072600			biological_process											owl:Class	
GO:0032789	biolink:NamedThing	unsaturated monocarboxylic acid metabolic process	The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds.	got7fsn_ti	unsaturated monocarboxylate metabolic process|unsaturated monocarboxylic acid metabolism													biological_process											owl:Class	
GO:0045111	biolink:NamedThing	intermediate filament cytoskeleton	Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0071702	biolink:NamedThing	organic substance transport	The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.	got7fsn_ti							mah	2010-03-08T02:15:14Z						biological_process											owl:Class	
GO:0099139	biolink:NamedThing	cheating during chimeric sorocarp development	Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes.	got7fsn_ti														biological_process											owl:Class	
GO:0016273	biolink:NamedThing	arginine N-methyltransferase activity	Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue.	got7fsn_ti														molecular_function											owl:Class	
GO:0001732	biolink:NamedThing	formation of cytoplasmic translation initiation complex	Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.	got7fsn_ti	formation of translation initiation complex|cytoplasmic translation initiation complex assembly|translation initiation complex assembly													biological_process											owl:Class	
GO:1990441	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter in response to ER stress|ER stress-induced negative regulation of transcription from RNA polymerase II promoter|reduction of transcription from RNA polymerase II promoter under ER stress|inhibition of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|down regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|down-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|repression of transcription from RNA polymerase II promoter under ER stress|suppression of transcription from RNA polymerase II promoter under ER stress						bf	2014-07-31T13:08:54Z						biological_process											owl:Class	
GO:0102711	biolink:NamedThing	gibberellin A25,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate + O2 <=> gibberellin A13 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-6541		molecular_function											owl:Class	
GO:0036173	biolink:NamedThing	thiosulfate binding	Binding to a thiosulfate, a sulfur oxide that has formula O3S2.	got7fsn_ti							bf	2012-03-29T10:38:15Z						molecular_function											owl:Class	
GO:0043168	biolink:NamedThing	anion binding	Binding to an anion, a charged atom or group of atoms with a net negative charge.	got7fsn_ti														molecular_function											owl:Class	
GO:0060253	biolink:NamedThing	negative regulation of glial cell proliferation	Any process that stops or decreases the rate or extent of glial cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0007234	biolink:NamedThing	osmosensory signaling via phosphorelay pathway	A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.	got7fsn_ti	signal transduction during osmotic stress via two-component system|osmolarity signalling pathway via two-component system|osmosensory signaling pathway via two-component system|osmolarity signaling pathway via two-component system|osmosensory signalling pathway via two-component system|osmolarity sensing via two-component system													biological_process											owl:Class	
GO:0044556	biolink:NamedThing	envenomation resulting in negative regulation of heart rate of other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism.	got7fsn_ti							jl	2012-03-29T03:04:52Z						biological_process											owl:Class	
GO:0046409	biolink:NamedThing	p-coumarate 3-hydroxylase activity	Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+.	got7fsn_ti	cytochrome P450 CYP98A3													molecular_function											owl:Class	
GO:0004653	biolink:NamedThing	polypeptide N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.	got7fsn_ti	UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity|UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity|UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity|polypeptide-N-acetylgalactosamine transferase activity|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity|protein-UDP acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity|UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity|glycoprotein acetylgalactosaminyltransferase activity|UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity											Reactome:R-HSA-8851619|EC:2.4.1.41|Reactome:R-HSA-913675|MetaCyc:2.4.1.41-RXN|Reactome:R-HSA-5096532|Reactome:R-HSA-9694438|Reactome:R-HSA-5096537|Reactome:R-HSA-9683760		molecular_function											owl:Class	
GO:0050631	biolink:NamedThing	corydaline synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP(+).	got7fsn_ti	S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase activity											RHEA:14773|MetaCyc:2.1.1.147-RXN|EC:2.1.1.147|KEGG_REACTION:R07241		molecular_function											owl:Class	
GO:0001405	biolink:NamedThing	PAM complex, Tim23 associated import motor	Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix.	got7fsn_ti	presequence translocase-associated import motor|pre-sequence translocase-associated import motor|PAM complex|mitochondrial import motor													cellular_component											owl:Class	
GO:0030626	biolink:NamedThing	U12 snRNA binding	Binding to a U12 small nuclear RNA (U12 snRNA).	got7fsn_ti														molecular_function											owl:Class	
GO:0036335	biolink:NamedThing	intestinal stem cell homeostasis	Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells.	got7fsn_ti							bf	2012-09-05T10:23:41Z						biological_process											owl:Class	
GO:0043056	biolink:NamedThing	forward locomotion	Anterior movement of an organism, following the direction of the head of the animal.	got7fsn_ti														biological_process											owl:Class	
GO:0019044	biolink:NamedThing	maintenance of viral latency	The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.	got7fsn_ti	prophage maintenance|latent virus maintenance|provirus maintenance										GO:0075716|GO:0032360			biological_process											owl:Class	
GO:0033772	biolink:NamedThing	flavonoid 3',5'-hydroxylase activity	Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O.	got7fsn_ti	F3'5'H|F3',5'H|flavanone,NADPH:oxygen oxidoreductase activity											MetaCyc:RXN-7783|MetaCyc:RXN-8671|RHEA:55448|EC:1.14.14.81		molecular_function											owl:Class	
GO:0044844	biolink:NamedThing	meiotic interphase II	The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).		jl	2014-03-26T16:52:27Z						biological_process											owl:Class	
GO:0005176	biolink:NamedThing	ErbB-2 class receptor binding	Binding to a protein-tyrosine kinase receptor Neu/ErbB-2/HER2.	got7fsn_ti	HER2 receptor binding|HER2 receptor ligand|ErbB-2 class receptor ligand|Neu receptor ligand|Neu receptor binding													molecular_function											owl:Class	
GO:0009389	biolink:NamedThing	dimethyl sulfoxide reductase activity	Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O.	got7fsn_ti	dimethyl sulphoxide reductase activity											UM-BBD_reactionID:r0207|EC:1.8.99.-		molecular_function											owl:Class	
GO:0034953	biolink:NamedThing	perillyl-CoA hydratase activity	Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r1002		molecular_function											owl:Class	
GO:0070652	biolink:NamedThing	HAUS complex	A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.	got7fsn_ti	HAUS augmin complex						mah	2009-05-28T03:21:01Z						cellular_component											owl:Class	
GO:0021669	biolink:NamedThing	rhombomere 6 formation	The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0015420	biolink:NamedThing	ABC-type vitamin B12 transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin.	got7fsn_ti	cobalamin-transporting ATPase activity|cobalamin porter activity|ATP-dependent vitamin B12 transmembrane transporter activity|cobalamin transporter activity|ATP-dependent cobalamin transmembrane transporter activity|vitamin B12 ABC transporter activity|vitamin B12-transporting ATPase activity|cobalamin ABC transporter|vitamin B12 porter activity|ATPase-coupled vitamin B12 transmembrane transporter activity|vitamin B12 transporter activity|ATPase-coupled cobalamin transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/21353									GO:0015235|GO:0102023	EC:7.6.2.8|RHEA:17873|MetaCyc:3.6.3.33-RXN|Reactome:R-HSA-3095901|Reactome:R-HSA-3315437|MetaCyc:ABC-5-RXN|Reactome:R-HSA-3000238		molecular_function											owl:Class	
GO:0044807	biolink:NamedThing	macrophage migration inhibitory factor production	The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	MIF production						jl	2013-09-11T12:04:09Z						biological_process											owl:Class	
GO:0004252	biolink:NamedThing	serine-type endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	got7fsn_ti	blood coagulation factor activity|serine elastase activity											Reactome:R-HSA-3788061|Reactome:R-HSA-1655842|Reactome:R-HSA-186785|Reactome:R-HSA-1602484|Reactome:R-HSA-9023196|Reactome:R-HSA-159733|Reactome:R-HSA-158333|EC:3.4.21.34|Reactome:R-HSA-140870|EC:3.4.21.61|Reactome:R-HSA-166792|Reactome:R-HSA-9668365|Reactome:R-HSA-173745|Reactome:R-HSA-1592278|Reactome:R-HSA-976743|Reactome:R-HSA-140777|Reactome:R-HSA-1604752|Reactome:R-HSA-1602473|Reactome:R-HSA-1181152|EC:3.4.21.71|EC:3.4.24.3|EC:3.4.21.36|Reactome:R-HSA-158766|EC:3.4.21.53|EC:3.4.21.54|Reactome:R-HSA-1602466|Reactome:R-HSA-5691512|Reactome:R-HSA-1592362|EC:3.4.21.26|EC:3.4.21.62|EC:3.4.21.89|Reactome:R-HSA-158313|Reactome:R-HSA-9694287|Reactome:R-HSA-1474197|Reactome:R-HSA-9033506|Reactome:R-HSA-140823|Reactome:R-HSA-2534260|EC:3.4.21.69|Reactome:R-HSA-9023178|EC:3.4.21.-|Reactome:R-HSA-2168960|Reactome:R-HSA-2514772|Reactome:R-HSA-1566962|Reactome:R-HSA-158925|Reactome:R-HSA-1604359|Reactome:R-HSA-174551|EC:3.4.21.9|EC:3.4.21.20|Reactome:R-HSA-114697|Reactome:R-HSA-9666383|EC:3.4.21.92|EC:3.4.21.5|Reactome:R-HSA-173680|Reactome:R-HSA-9033524|Reactome:R-HSA-8874186|Reactome:R-HSA-381466|Reactome:R-HSA-163798|Reactome:R-HSA-9023626|Reactome:R-HSA-6807224|EC:3.4.21.75|Reactome:R-HSA-1912372|EC:3.4.21.10|Reactome:R-HSA-1604763|Reactome:R-HSA-9033520|Reactome:R-HSA-140599|Reactome:R-HSA-1592316|Reactome:R-HSA-8874205|Reactome:R-HSA-9694661|Reactome:R-HSA-1604690|EC:3.4.21.87|Reactome:R-HSA-141026|Reactome:R-HSA-140840|Reactome:R-HSA-8874206|Reactome:R-HSA-6800299|Reactome:R-HSA-159773|Reactome:R-HSA-400496|Reactome:R-HSA-2214330|Reactome:R-HSA-9686710|Reactome:R-HSA-6800198|Reactome:R-HSA-158747|Reactome:R-HSA-9033515|Reactome:R-HSA-1592371|Reactome:R-HSA-422021|Reactome:R-HSA-158300|Reactome:R-HSA-2482180|Reactome:R-HSA-381446|Reactome:R-HSA-3928657|Reactome:R-HSA-1604741|EC:3.4.21.59|Reactome:R-HSA-8865276|Reactome:R-HSA-5210935|EC:3.4.21.73|Reactome:R-HSA-9033530|EC:3.4.21.46|EC:3.4.21.4|Reactome:R-HSA-2172405|Reactome:R-HSA-8849857|Reactome:R-HSA-1454843|Reactome:R-HSA-1592297|Reactome:R-HSA-159868|Reactome:R-HSA-1592436|Reactome:R-HSA-1912369|Reactome:R-HSA-158137|Reactome:R-HSA-1604360|EC:3.4.21.6|Reactome:R-HSA-422051|Reactome:R-HSA-8850831|Reactome:R-HSA-2022411|Reactome:R-HSA-183130|Reactome:R-HSA-5607002|Reactome:R-HSA-158164|Reactome:R-HSA-9686731|EC:3.4.21.27|EC:3.4.21.45|EC:3.4.21.47|MetaCyc:ACYLAMINOACYL-PEPTIDASE-RXN|EC:3.4.21.48|Reactome:R-HSA-8852716|Reactome:R-HSA-140696|Reactome:R-HSA-977371|Reactome:R-HSA-2534206|Reactome:R-HSA-171288|Reactome:R-HSA-381798|Reactome:R-HSA-1604732|EC:3.4.21.68|Reactome:R-HSA-159771|EC:3.4.21.7|EC:3.4.21.21|Reactome:R-HSA-3785684|Reactome:R-HSA-9023627|Reactome:R-HSA-2534160|Reactome:R-HSA-158744|Reactome:R-HSA-6801687|EC:3.4.24.7|Reactome:R-HSA-158311|Reactome:R-HSA-3266557|Reactome:R-HSA-141040|Reactome:R-HSA-265301|EC:3.4.21.43|Reactome:R-HSA-8855825|Reactome:R-HSA-1602458|Reactome:R-HSA-9699007|Reactome:R-HSA-381135|Reactome:R-HSA-166753|Reactome:R-HSA-382061|EC:3.4.21.41|Reactome:R-HSA-9670874|Reactome:R-HSA-9653249|Reactome:R-HSA-170844|EC:3.4.21.22|Reactome:R-HSA-9033490|Reactome:R-HSA-9023632|Reactome:R-HSA-173626|Reactome:R-HSA-139893|Reactome:R-HSA-5578783|Reactome:R-HSA-6800200|Reactome:R-HSA-9655046|EC:3.4.21.93|Reactome:R-HSA-140769|Reactome:R-HSA-1604368|Reactome:R-HSA-158942|Reactome:R-HSA-140736|EC:3.4.21.42|Reactome:R-HSA-8865275|Reactome:R-HSA-166817|Reactome:R-HSA-2471621|Reactome:R-HSA-9668253|Reactome:R-HSA-381500|Reactome:R-HSA-3814820|Reactome:R-HSA-1592398|EC:3.4.24.34|EC:3.4.21.39|Reactome:R-HSA-1566979|EC:3.4.19.1|Reactome:R-HSA-9023633|EC:3.4.21.79|EC:3.4.21.94|Reactome:R-HSA-8849826|Reactome:R-HSA-9673223|Reactome:R-HSA-140700|Reactome:R-HSA-2168923|Reactome:R-HSA-8874212|Reactome:R-HSA-1592270|Reactome:R-HSA-400459|Reactome:R-HSA-159728|Reactome:R-HSA-163843|Reactome:R-HSA-187020|Reactome:R-HSA-159796|Reactome:R-HSA-1602488|Reactome:R-HSA-1604731|Reactome:R-HSA-977615|EC:3.4.21.35|Reactome:R-HSA-2514823|Reactome:R-HSA-1604712|Reactome:R-HSA-2129357|EC:3.4.21.102|Reactome:R-HSA-5591040|Reactome:R-HSA-400492|Reactome:R-HSA-158750|Reactome:R-HSA-9662786|Reactome:R-HSA-140664|Reactome:R-HSA-1604722|Reactome:R-HSA-8874204|Reactome:R-HSA-5210912|EC:3.4.21.83|Reactome:R-HSA-158419|EC:3.4.21.38|Reactome:R-HSA-1566981|EC:3.4.21.1|Reactome:R-HSA-9033529|EC:3.4.21.78|Reactome:R-HSA-173631|Reactome:R-HSA-2471842|Reactome:R-HSA-158982|Reactome:R-HSA-1592314|Reactome:R-HSA-183122|EC:3.4.21.88|Reactome:R-HSA-381461|Reactome:R-HSA-1799329		molecular_function											owl:Class	
GO:0051840	biolink:NamedThing	negative regulation by host of cytolysis of symbiont cells	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	down regulation by host of cytolysis of symbiont cells|downregulation by host of cytolysis of symbiont cells|inhibition by host of cytolysis of symbiont cells|down-regulation by host of cytolysis of symbiont cells													biological_process											owl:Class	
GO:0051803	biolink:NamedThing	negative regulation of cytolysis in other organism involved in symbiotic interaction	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	down regulation of cytolysis of cells in other organism during symbiotic interaction|inhibition of cytolysis of cells in other organism during symbiotic interaction|downregulation of cytolysis of cells in other organism during symbiotic interaction|negative regulation of cytolysis of cells in other organism during symbiotic interaction|down-regulation of cytolysis of cells in other organism during symbiotic interaction|negative regulation of cytolysis of cells in other organism involved in symbiotic interaction													biological_process											owl:Class	
GO:0140232	biolink:NamedThing	intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the presynaptic membrane potential.	got7fsn_ti	intracellular cAMP activated cation channel activity involved in regulation of presynaptic membrane potential	https://github.com/geneontology/synapse/issues/231			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-09T11:30:40Z						molecular_function											owl:Class	
GO:0005222	biolink:NamedThing	intracellular cAMP-activated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	intracellular adenosine 3',5'-cyclophosphate activated cation channel activity|intracellular 3',5' cAMP activated cation channel activity|intracellular 3',5'-cAMP activated cation channel activity|intracellular cAMP activated cation channel activity|hyperpolarization-activated cyclic nucleotide-gated channel activity|intracellular cyclic AMP activated cation channel activity|HCN channel activity													molecular_function											owl:Class	
GO:0090550	biolink:NamedThing	response to molybdenum starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum.	got7fsn_ti							tb	2013-04-22T13:57:16Z						biological_process											owl:Class	
GO:0036191	biolink:NamedThing	indolin-2-one monooxygenase activity	Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O.	got7fsn_ti	indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)						bf	2012-04-19T11:38:01Z				RHEA:31919|EC:1.14.14.157|KEGG_REACTION:R07421		molecular_function											owl:Class	
GO:0032202	biolink:NamedThing	telomere assembly	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins.	got7fsn_ti	telomere formation													biological_process											owl:Class	
GO:0051923	biolink:NamedThing	sulfation	The addition of a sulfate group to a molecule.	got7fsn_ti	sulfonation|phase II metabolism|sulphur addition|sulfur addition|sulphation													biological_process											owl:Class	
GO:0048017	biolink:NamedThing	inositol lipid-mediated signaling	A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids.	got7fsn_ti	inositol phospholipid-mediated signaling|inositol lipid-mediated signal transduction|inositol lipid-mediated signalling													biological_process											owl:Class	
GO:0099126	biolink:NamedThing	transforming growth factor beta complex	A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP.	got7fsn_ti	TGF-beta complex|TGFbeta complex|TGF-beta dimer|TGFB dimer|TGFbeta dimer|TGFB complex													cellular_component											owl:Class	
GO:0018712	biolink:NamedThing	3-hydroxybutyryl-CoA thiolase activity	Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0010|MetaCyc:R7-RXN		molecular_function											owl:Class	
GO:0020027	biolink:NamedThing	hemoglobin metabolic process	The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.	got7fsn_ti	hemoglobin metabolism|haemoglobin metabolic process|haemoglobin metabolism													biological_process											owl:Class	
GO:0110001	biolink:NamedThing	toxin-antitoxin complex	A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon.	got7fsn_ti					An example is YoeB (P69348) in Escherichia coli in PMID:16109374 (inferred by direct evidence).		kmv							cellular_component											owl:Class	
GO:0102369	biolink:NamedThing	11alpha-30-dihydroxy beta-amyrin dehydrogenase activity	Catalysis of the reaction: 11alpha,30-dihydroxy-beta-amyrin + NADPH + O2 + H+ <=> 30-hydroxy-11-oxo-beta-amyrin + NADP + 2 H2O.	got7fsn_ti												MetaCyc:RXN-13491		molecular_function											owl:Class	
GO:0010245	biolink:NamedThing	radial microtubular system formation	Formation of radial microtubular systems during male meiotic cytokinesis in plants.	got7fsn_ti														biological_process											owl:Class	
GO:0071040	biolink:NamedThing	nuclear polyadenylation-dependent antisense transcript catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.	got7fsn_ti	nuclear poly(A)-dependent antisense transcript catabolic process						krc	2009-07-29T01:25:21Z						biological_process											owl:Class	
GO:0050818	biolink:NamedThing	regulation of coagulation	Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.	got7fsn_ti	regulation of clotting													biological_process											owl:Class	
GO:0035115	biolink:NamedThing	embryonic forelimb morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.	got7fsn_ti	embryonic arm morphogenesis										GO:0035117			biological_process											owl:Class	
GO:0035714	biolink:NamedThing	cellular response to nitrogen dioxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.	got7fsn_ti	cellular response to NO2						bf	2011-03-02T03:16:37Z						biological_process											owl:Class	
GO:0045436	biolink:NamedThing	lycopene beta cyclase activity	Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively.	got7fsn_ti	lycopene cyclase|crtL											RHEA:32219|MetaCyc:RXN1F-150		molecular_function											owl:Class	
GO:0052781	biolink:NamedThing	chitobiose catabolic process	The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.	got7fsn_ti							ai	2011-10-03T08:54:17Z						biological_process											owl:Class	
GO:0052782	biolink:NamedThing	amino disaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.	got7fsn_ti							ai	2011-10-03T08:56:04Z						biological_process											owl:Class	
GO:0014863	biolink:NamedThing	detection of inactivity	The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0098826	biolink:NamedThing	endoplasmic reticulum tubular network membrane	The membrane of the endoplasmic reticulum tubular network.	got7fsn_ti														cellular_component											owl:Class	
GO:0022872	biolink:NamedThing	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	mannitol PTS transporter activity													molecular_function											owl:Class	
GO:0015575	biolink:NamedThing	mannitol transmembrane transporter activity	Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.	got7fsn_ti	mannitol permease activity										GO:0015586			molecular_function											owl:Class	
GO:0000406	biolink:NamedThing	double-strand/single-strand DNA junction binding	Binding to a DNA segment that contains double-stranded DNA flanked by a region of single-stranded DNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0050400	biolink:NamedThing	xylitol kinase activity	Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate.	got7fsn_ti	ATP:xylitol 5-phosphotransferase activity|xylitol phosphotransferase activity											RHEA:20209|EC:2.7.1.122|KEGG_REACTION:R02136|MetaCyc:XYLITOL-KINASE-RXN		molecular_function											owl:Class	
GO:0102786	biolink:NamedThing	stearoyl-[acp] desaturase activity	Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin.	got7fsn_ti												EC:1.14.19.2|MetaCyc:RXN-7903|RHEA:11776		molecular_function											owl:Class	
GO:2001308	biolink:NamedThing	gliotoxin metabolic process	The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.	got7fsn_ti	gliotoxin metabolism						pr	2012-03-15T03:42:10Z						biological_process											owl:Class	
GO:0097139	biolink:NamedThing	BID-BCL-2 complex	A heterodimeric protein complex consisting of BID and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:40:31Z						cellular_component											owl:Class	
GO:0003145	biolink:NamedThing	embryonic heart tube formation via epithelial folding	The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.	got7fsn_ti							tb	2009-09-22T04:26:03Z						biological_process											owl:Class	
GO:0002504	biolink:NamedThing	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.	got7fsn_ti	peptide or polysaccharide antigen processing and presentation of via MHC class II													biological_process											owl:Class	
GO:0033604	biolink:NamedThing	negative regulation of catecholamine secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.	got7fsn_ti	downregulation of catecholamine secretion|down regulation of catecholamine secretion|down-regulation of catecholamine secretion|inhibition of catecholamine secretion													biological_process											owl:Class	
GO:0003962	biolink:NamedThing	cystathionine gamma-synthase activity	Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate.	got7fsn_ti	homoserine O-transsuccinylase activity|O-succinyl-L-homoserine (thiol)-lyase activity|O-succinyl-L-homoserine succinate-lyase (adding cysteine) activity|O-succinylhomoserine synthase activity|cystathionine g-synthase activity|CTT gamma synthase activity|O-succinylhomoserine synthetase activity|cystathionine synthase activity|O-succinylhomoserine (thiol)-lyase activity|cystathionine synthetase activity|O-succinyl-L-homoserine succinate-lyase activity|O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase activity|cystathionine gamma synthase activity|homoserine transsuccinylase activity										GO:0000505	EC:2.5.1.48|MetaCyc:O-SUCCHOMOSERLYASE-RXN|RHEA:20397		molecular_function											owl:Class	
GO:0033016	biolink:NamedThing	rhoptry membrane	The lipid bilayer surrounding a rhoptry.	got7fsn_ti														cellular_component											owl:Class	
GO:0047844	biolink:NamedThing	deoxycytidine deaminase activity	Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.	got7fsn_ti	deoxycytidine aminohydrolase activity											EC:3.5.4.14|MetaCyc:CYTIDEAM-RXN|RHEA:13433		molecular_function											owl:Class	
GO:0045454	biolink:NamedThing	cell redox homeostasis	Any process that maintains the redox environment of a cell or compartment within a cell.	got7fsn_ti	regulation of redox homeostasis|regulation of cell redox homeostasis										GO:0045867|GO:0045868|GO:0030503	Wikipedia:Redox		biological_process											owl:Class	
GO:0010112	biolink:NamedThing	regulation of systemic acquired resistance	Any process that modulates the frequency, rate or extent of systemic acquired resistance.	got7fsn_ti														biological_process											owl:Class	
GO:0047910	biolink:NamedThing	galactose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH.	got7fsn_ti	D-galactose:NADP+ 1-oxidoreductase activity|D-galactose dehydrogenase (NADP+)											MetaCyc:GALACTOSE-1-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.120|RHEA:18625		molecular_function											owl:Class	
GO:0050374	biolink:NamedThing	UDP-galacturonate decarboxylase activity	Catalysis of the reaction: H(+) + UDP-alpha-D-galacturonate = CO(2) + UDP-L-arabinose.	got7fsn_ti	UDPGalUA carboxy lyase activity|UDP-D-galacturonate carboxy-lyase (UDP-L-arabinose-forming)|UDP-galacturonic acid decarboxylase activity|UDP-D-galacturonate carboxy-lyase activity|UDPgalacturonate decarboxylase activity											MetaCyc:UDP-GALACTURONATE-DECARBOXYLASE-RXN|EC:4.1.1.67|RHEA:19725|KEGG_REACTION:R02636		molecular_function											owl:Class	
GO:0060152	biolink:NamedThing	microtubule-based peroxisome localization	The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	got7fsn_ti	microtubule-based peroxisome localisation													biological_process											owl:Class	
BFO:0000040	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033959	biolink:NamedThing	deoxyribodipyrimidine endonucleosidase activity	Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue.	got7fsn_ti	PD-DNA glycosylase activity|deoxyribonucleate pyrimidine dimer glycosidase activity|pyrimidine dimer DNA glycosylase activity|endonuclease V activity|deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase activity|pyrimidine dimer DNA-glycosylase activity|T4-induced UV endonuclease activity											EC:3.2.2.17|MetaCyc:3.2.2.17-RXN		molecular_function											owl:Class	
GO:0110019	biolink:NamedThing	IRES-dependent translational initiation of circular RNA	The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.	got7fsn_ti	IRES-dependent translational initiation of circRNA						kmv	2017-06-08T15:36:38Z						biological_process											owl:Class	
GO:0018304	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulphide											RESID:AA0286		biological_process											owl:Class	
GO:0043332	biolink:NamedThing	mating projection tip	The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.	got7fsn_ti	conjugation tube tip|shmoo tip													cellular_component											owl:Class	
GO:0018472	biolink:NamedThing	1-hydroxy-2-naphthaldehyde dehydrogenase activity	Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate.	got7fsn_ti												UM-BBD_reactionID:r0485		molecular_function											owl:Class	
GO:0035241	biolink:NamedThing	protein-arginine omega-N monomethyltransferase activity	Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue.  The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine.	got7fsn_ti	S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega-methyl-L-arginine-forming)|type III protein arginine methyltransferase activity				Type III protein arginine methyltransferases catalyze the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein. Unlike type I and type II protein arginine methyltransferases, which also catalyze this reaction, type III enzymes do not methylate the substrate any further.							RESID:AA0069|RHEA:48100|EC:2.1.1.321		molecular_function											owl:Class	
GO:0018007	biolink:NamedThing	N-terminal peptidyl-glycine N-glucuronylation	The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine.	got7fsn_ti												RESID:AA0058		biological_process											owl:Class	
GO:0047780	biolink:NamedThing	citrate dehydratase activity	Catalysis of the reaction: citrate = cis-aconitate + H2O.	got7fsn_ti	aconitate hydratase activity|citrate hydro-lyase (cis-aconitate-forming) activity|citrate hydro-lyase (cis-aconitate-forming)|citrate hydro-lyase activity				This term is also a sub-reaction of 'aconitate hydratase activity ; GO:0003994 (EC:4.2.1.3)'.						GO:0052632	MetaCyc:ACONITATEDEHYDR-RXN|RHEA:10228|KEGG_REACTION:R01325|EC:4.2.1.3|MetaCyc:CITRATE-DEHYDRATASE-RXN		molecular_function											owl:Class	
GO:0050224	biolink:NamedThing	prunasin beta-glucosidase activity	Catalysis of the reaction: (R)-prunasin + H(2)O = D-glucose + mandelonitrile.	got7fsn_ti	prunasin beta-D-glucohydrolase activity|prunasin hydrolase activity|prunasin b-glucosidase activity											MetaCyc:PRUNASIN-BETA-GLUCOSIDASE-RXN|EC:3.2.1.118|KEGG_REACTION:R02558|RHEA:16489		molecular_function											owl:Class	
GO:0014818	biolink:NamedThing	skeletal muscle satellite cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0003427	biolink:NamedThing	regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.	got7fsn_ti	regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division by planar cell polarity pathway						dph	2009-12-22T11:43:29Z						biological_process											owl:Class	
GO:0099575	biolink:NamedThing	regulation of protein catabolic process at presynapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0098913	biolink:NamedThing	membrane depolarization during ventricular cardiac muscle cell action potential	The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	got7fsn_ti	ventricular depolarization|electrocardiogram QRS complex													biological_process											owl:Class	
GO:0052616	biolink:NamedThing	ent-kaur-16-en-19-ol oxidase activity	Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al.	got7fsn_ti												RHEA:21304|MetaCyc:RXN-5242|EC:1.14.14.86		molecular_function											owl:Class	
GO:0120269	biolink:NamedThing	ciliary centrin arm	A rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20062			Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.		krc	2020-09-30T18:20:22Z						cellular_component											owl:Class	
GO:0050502	biolink:NamedThing	cis-zeatin O-beta-D-glucosyltransferase activity	Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H(+) + UDP.	got7fsn_ti	UDPglucose:cis-zeatin O-beta-D-glucosyltransferase activity|cis-zeatin O-b-D-glucosyltransferase activity|UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase activity											MetaCyc:RXN-4735|KEGG_REACTION:R07260|EC:2.4.1.215|RHEA:20681		molecular_function											owl:Class	
GO:0021847	biolink:NamedThing	ventricular zone neuroblast division	The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially.	got7fsn_ti	neuroblast division in ventricular zone													biological_process											owl:Class	
GO:0018216	biolink:NamedThing	peptidyl-arginine methylation	The addition of a methyl group to an arginine residue in a protein.	got7fsn_ti											GO:0018017			biological_process											owl:Class	
GO:0043883	biolink:NamedThing	malolactic enzyme activity	Catalysis of the reaction: malate + H+ = L-lactate + CO2.	got7fsn_ti	MleS				This function is part of the process of degradation of L-malic acid by lactic acid bacteria.									molecular_function											owl:Class	
GO:0055005	biolink:NamedThing	ventricular cardiac myofibril assembly	The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.	got7fsn_ti	ventricular heart myofibril development|ventricular cardiac myofibril development													biological_process											owl:Class	
GO:0043587	biolink:NamedThing	tongue morphogenesis	The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.	got7fsn_ti	lingua morphogenesis|glossa morphogenesis													biological_process											owl:Class	
GO:0097585	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p.	got7fsn_ti	Pmt5p-Pmt3p complex						pr	2014-03-02T18:18:28Z						cellular_component											owl:Class	
GO:1902493	biolink:NamedThing	acetyltransferase complex	A protein complex which is capable of acetyltransferase activity.	got7fsn_ti							bhm	2013-11-13T16:16:45Z						cellular_component											owl:Class	
GO:0019875	biolink:NamedThing	6-aminohexanoate-dimer hydrolase activity	Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate.	got7fsn_ti	N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase activity|6-aminohexanoic acid oligomer hydrolase activity											RHEA:21364|EC:3.5.1.46|MetaCyc:RXN-3962|UM-BBD_enzymeID:e0673		molecular_function											owl:Class	
GO:0008653	biolink:NamedThing	lipopolysaccharide metabolic process	The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.	got7fsn_ti	lipopolysaccharide metabolism|LPS metabolic process													biological_process											owl:Class	
GO:0051271	biolink:NamedThing	negative regulation of cellular component movement	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component.	got7fsn_ti	negative regulation of cellular component motion													biological_process											owl:Class	
GO:0036472	biolink:NamedThing	suppression by virus of host protein-protein interaction	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interaction between host proteins.	got7fsn_ti	suppression by virus of host protein:protein binding|suppression by virus of host protein interaction|suppression by virus of host protein binding|suppression by virus of host protein:protein interaction						bf	2014-07-21T11:18:51Z						biological_process											owl:Class	
GO:0050073	biolink:NamedThing	macrolide 2'-kinase activity	Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2'-O-phosphate.	got7fsn_ti	ATP:macrolide 2'-O-phosphotransferase activity											KEGG_REACTION:R03780|MetaCyc:MACROLIDE-2-KINASE-RXN|EC:2.7.1.136|RHEA:18333		molecular_function											owl:Class	
GO:0050099	biolink:NamedThing	methylglutamate dehydrogenase activity	Catalysis of the reaction: N-methyl-L-glutamate + A + H(2)O = L-glutamate + AH(2) + formaldehyde.	got7fsn_ti	N-methyl-L-glutamate:(acceptor) oxidoreductase (demethylating)|N-methyl-L-glutamate:acceptor oxidoreductase (demethylating)|N-methylglutamate dehydrogenase activity											MetaCyc:METHYLGUTAMATE-DEHYDROGENASE-RXN|RHEA:22572|KEGG_REACTION:R00609|EC:1.5.99.5		molecular_function											owl:Class	
GO:0051055	biolink:NamedThing	negative regulation of lipid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.	got7fsn_ti	negative regulation of lipogenesis|inhibition of lipid biosynthetic process|negative regulation of lipid synthesis|negative regulation of lipid biosynthesis|negative regulation of lipid formation|downregulation of lipid biosynthetic process|negative regulation of lipid anabolism|down regulation of lipid biosynthetic process|down-regulation of lipid biosynthetic process													biological_process											owl:Class	
GO:0070246	biolink:NamedThing	natural killer cell apoptotic process	Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation.	got7fsn_ti	NK cell apoptosis|natural killer cell apoptosis													biological_process											owl:Class	
GO:0045548	biolink:NamedThing	phenylalanine ammonia-lyase activity	Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.	got7fsn_ti	phe ammonia-lyase activity|PAL activity|phenylalanine ammonium-lyase activity|phenylalanine deaminase activity|L-phenylalanine ammonia-lyase activity											EC:4.3.1.24|EC:4.3.1.25|RHEA:21384		molecular_function											owl:Class	
GO:0047967	biolink:NamedThing	glycyrrhizinate beta-glucuronidase activity	Catalysis of the reaction: glycyrrhizate + H(2)O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate.	got7fsn_ti	glycyrrhizin hydrolase activity|glycyrrhizinate glucuronosylhydrolase activity|glycyrrhizinic acid hydrolase activity|glycyrrhizinate b-glucuronidase activity|glycyrrhizin beta-hydrolase activity											KEGG_REACTION:R03906|MetaCyc:GLYCYRRHIZINATE-BETA-GLUCURONIDASE-RXN|RHEA:17369|EC:3.2.1.128		molecular_function											owl:Class	
GO:0071169	biolink:NamedThing	establishment of protein localization to chromatin	The directed movement of a protein to a part of a chromosome that is organized into chromatin.	got7fsn_ti	establishment of protein localisation to chromatin						mah	2009-11-20T11:52:43Z						biological_process											owl:Class	
GO:0004417	biolink:NamedThing	hydroxyethylthiazole kinase activity	Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+).	got7fsn_ti	ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase activity|4-methyl-5-(beta-hydroxyethyl)thiazole kinase activity|hydroxyethylthiazole kinase (phosphorylating)											RHEA:24212|EC:2.7.1.50|MetaCyc:THIAZOLSYN3-RXN|KEGG_REACTION:R04448		molecular_function											owl:Class	
GO:0042367	biolink:NamedThing	biotin catabolic process	The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.	got7fsn_ti	biotin catabolism|biotin degradation|vitamin B7 catabolic process|vitamin H catabolic process|vitamin B7 catabolism|biotin breakdown|vitamin H catabolism													biological_process											owl:Class	
GO:0005675	biolink:NamedThing	transcription factor TFIIH holo complex	A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of  the core TFIIH complex and the TFIIK complex.	got7fsn_ti	holo TFIIH complex													cellular_component											owl:Class	
GO:0034553	biolink:NamedThing	mitochondrial respiratory chain complex II assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0071245	biolink:NamedThing	cellular response to carbon monoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.	got7fsn_ti							mah	2009-12-03T02:44:43Z						biological_process											owl:Class	
GO:0061612	biolink:NamedThing	galactose to glucose-1-phosphate metabolic process	The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate.	got7fsn_ti							dph	2014-04-04T08:18:49Z						biological_process											owl:Class	
GO:0006012	biolink:NamedThing	galactose metabolic process	The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.	got7fsn_ti	galactose metabolism											Wikipedia:Galactose		biological_process											owl:Class	
GO:0097414	biolink:NamedThing	classical Lewy body	Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.	got7fsn_ti	brainstem Lewy body						pr	2012-11-06T16:27:41Z				NIF_Subcellular:sao4749542545		cellular_component											owl:Class	
GO:0019714	biolink:NamedThing	peptidyl-glutamine esterification	The addition of an ester group to a glutamine residue in a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0008574	biolink:NamedThing	plus-end-directed microtubule motor activity	A motor activity that generates movement along a microtubule toward the plus end, driven by ATP hydrolysis.	got7fsn_ti	microtubule motor activity, plus-end-directed|kinesin activity|plus-end-directed ATP-dependent microtubule motor activity|ATP-dependent plus-end-directed microtubule motor activity|ATP-dependent microtubule motor activity, plus-end-directed|plus-end-directed kinesin ATPase activity|kinesin ATP phosphohydrolase (plus-end-directed)	https://github.com/geneontology/go-ontology/issues/18664										MetaCyc:3.6.4.4-RXN|EC:5.6.1.3		molecular_function											owl:Class	
GO:0014033	biolink:NamedThing	neural crest cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.	got7fsn_ti														biological_process											owl:Class	
GO:0050006	biolink:NamedThing	isomaltulose synthase activity	Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose.	got7fsn_ti	sucrose glucosylmutase activity|isomaltulose synthetase activity|sucrose alpha-glucosyltransferase activity|trehalulose synthase activity											RHEA:24032|EC:5.4.99.11|MetaCyc:ISOMALTULOSE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0035712	biolink:NamedThing	T-helper 2 cell activation	The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti	Th2 cell activation						bf	2011-03-02T03:05:59Z						biological_process											owl:Class	
GO:0047658	biolink:NamedThing	alpha-amino-acid esterase activity	Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol.	got7fsn_ti	alpha-amino-acid-ester aminoacylhydrolase activity|alpha-amino acid ester hydrolase activity|alpha-amino-acid ester hydrolase activity|a-amino-acid esterase activity											MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN|RHEA:17241|EC:3.1.1.43|Reactome:R-HSA-6784959		molecular_function											owl:Class	
GO:0005690	biolink:NamedThing	U4atac snRNP	A ribonucleoprotein complex that contains small nuclear RNA U4atac, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4atac snRNP, most of which remain associated with the U4atac snRNA both while the U4atac snRNP is free or assembled into the U4atac/U6atac complex or into a series of spliceosomal complexes.	got7fsn_ti	snRNP U4atac													cellular_component											owl:Class	
GO:0030740	biolink:NamedThing	inositol 3-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	myo-inositol 1-O-methyltransferase activity|S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase activity|S-adenosylmethionine:myo-inositol 1-methyltransferase activity|myo-inositol 1-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)|myo-inositol 1-methyltransferase activity|inositol L-1-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase activity											MetaCyc:MYO-INOSITOL-1-O-METHYLTRANSFERASE-RXN|EC:2.1.1.39|RHEA:18877|KEGG_REACTION:R01189		molecular_function											owl:Class	
GO:0034572	biolink:NamedThing	monodemethylisoproturon dimethylaminedehydrogenase activity	Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-.	got7fsn_ti												EC:1.5.99.-|UM-BBD_reactionID:r0897		molecular_function											owl:Class	
GO:1990405	biolink:NamedThing	protein antigen binding	Binding to a protein antigen.	got7fsn_ti							pm	2014-06-30T13:19:55Z						molecular_function											owl:Class	
GO:0014821	biolink:NamedThing	phasic smooth muscle contraction	A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.	got7fsn_ti														biological_process											owl:Class	
GO:1990312	biolink:NamedThing	type-II cohesin domain binding	Binding to a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain.	got7fsn_ti							tt	2014-03-07T04:51:07Z						molecular_function											owl:Class	
GO:0005824	biolink:NamedThing	outer plaque of spindle pole body	One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm.	got7fsn_ti														cellular_component											owl:Class	
GO:0071773	biolink:NamedThing	cellular response to BMP stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.	got7fsn_ti	cellular response to bone morphogenetic protein stimulus						mah	2010-08-31T11:04:45Z						biological_process											owl:Class	
GO:0102488	biolink:NamedThing	dTTP phosphohydrolase activity	Catalysis of the reaction: dTTP + 2 H2O = dTMP + 2 hydrogenphosphate + 2 H+.	got7fsn_ti												MetaCyc:RXN-14200|EC:3.6.1.5		molecular_function											owl:Class	
GO:0032634	biolink:NamedThing	interleukin-5 production	The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-5 biosynthetic process|interleukin-5 secretion|IL-5 production										GO:0072603|GO:0042225			biological_process											owl:Class	
GO:0047770	biolink:NamedThing	carboxylate reductase activity	Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor.	got7fsn_ti	carboxylic acid reductase activity|aldehyde:(acceptor) oxidoreductase activity|aldehyde:acceptor oxidoreductase activity											MetaCyc:CARBOXYLATE-REDUCTASE-RXN|EC:1.2.99.6		molecular_function											owl:Class	
GO:1990362	biolink:NamedThing	butanol dehydrogenase activity	Catalysis of the reaction: butanal + NADH + H+ => n-butanol + NAD+.	got7fsn_ti							tt	2014-04-23T21:14:09Z				RHEA:33199		molecular_function											owl:Class	
GO:0047960	biolink:NamedThing	glycine dehydrogenase activity	Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH.	got7fsn_ti	glycine:NAD+ oxidoreductase (deaminating)											EC:1.4.1.10|MetaCyc:GLYCINE-DEHYDROGENASE-RXN|RHEA:15721		molecular_function											owl:Class	
GO:0070836	biolink:NamedThing	caveola assembly	The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.	got7fsn_ti	caveolar biogenesis|caveola formation						mah	2009-07-30T04:45:54Z						biological_process											owl:Class	
GO:0038152	biolink:NamedThing	C-C chemokine receptor CCR4 signaling pathway	A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	chemokine receptor CCR4 signaling pathway|C-C chemokine receptor type 4 signaling pathway						bf	2012-05-11T11:43:34Z						biological_process											owl:Class	
GO:0071787	biolink:NamedThing	endoplasmic reticulum tubular network formation	The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.	got7fsn_ti	endoplasmic reticulum tubular network assembly|ER tubular network formation|ER tubular network assembly						mah	2010-09-01T01:54:29Z						biological_process											owl:Class	
GO:0016040	biolink:NamedThing	glutamate synthase (NADH) activity	Catalysis of the reaction: 2 L-glutamate + NAD(+) = 2-oxoglutarate + L-glutamine + H(+) + NADH.	got7fsn_ti	L-glutamate synthetase activity|glutamate (reduced nicotinamide adenine dinucleotide) synthase|L-glutamate:NAD+ oxidoreductase (transaminating)|L-glutamate synthase (NADH)|NADH: GOGAT|L-glutamate synthase activity|GOGAT activity|NADH-dependent glutamate synthase activity|NADH-glutamate synthase activity											RHEA:13753|KEGG_REACTION:R00093|MetaCyc:GLUTAMATE-SYNTHASE-NADH-RXN|EC:1.4.1.14		molecular_function											owl:Class	
GO:0018770	biolink:NamedThing	6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity	Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+.	got7fsn_ti												UM-BBD_reactionID:r0444		molecular_function											owl:Class	
GO:0061799	biolink:NamedThing	cyclic pyranopterin monophosphate synthase activity	Catalysis of the reaction:  (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.	got7fsn_ti							dph	2016-10-06T14:36:56Z				MetaCyc:RXN-17809|EC:4.6.1.17|RHEA:49580		molecular_function											owl:Class	
GO:0102264	biolink:NamedThing	tRNA-dihydrouridine20 synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) <=> H+ + a uracil20 in tRNA + NAD(P)H.	got7fsn_ti												EC:1.3.1.91|MetaCyc:RXN-12456		molecular_function											owl:Class	
GO:0033454	biolink:NamedThing	GCC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GCC codon.	got7fsn_ti	alanine tRNA				Note that in the standard genetic code, GCC codes for alanine.									molecular_function											owl:Class	
GO:0009052	biolink:NamedThing	pentose-phosphate shunt, non-oxidative branch	The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.	got7fsn_ti	pentose-phosphate pathway, non-oxidative branch|pentose phosphate shunt, non-oxidative branch|pentose phosphate pathway, non-oxidative branch											MetaCyc:NONOXIPENT-PWY|MetaCyc:P21-PWY		biological_process											owl:Class	
GO:0048535	biolink:NamedThing	lymph node development	The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.	got7fsn_ti	lymph gland development													biological_process											owl:Class	
GO:0060337	biolink:NamedThing	type I interferon signaling pathway	A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	type I interferon-mediated signaling pathway|type I interferon-activated signaling pathway|type I interferon-mediated signalling pathway													biological_process											owl:Class	
GO:0097600	biolink:NamedThing	exoxylanase activity	A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains.	got7fsn_ti							pr	2014-05-06T13:48:27Z						molecular_function											owl:Class	
GO:0048391	biolink:NamedThing	intermediate mesoderm formation	The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	got7fsn_ti														biological_process											owl:Class	
GO:0035641	biolink:NamedThing	locomotory exploration behavior	The specific movement from place to place of an organism in response to a novel environment.	got7fsn_ti							bf	2011-01-19T10:40:04Z						biological_process											owl:Class	
GO:0019585	biolink:NamedThing	glucuronate metabolic process	The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	got7fsn_ti	glucuronate metabolism										GO:0019699	Wikipedia:Glucuronic_acid		biological_process											owl:Class	
GO:0072572	biolink:NamedThing	poly-ADP-D-ribose binding	Binding to polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.	got7fsn_ti	poly-ADP-ribose binding|pADPr binding						mah	2011-01-31T02:49:04Z						molecular_function											owl:Class	
GO:0042803	biolink:NamedThing	protein homodimerization activity	Binding to an identical protein to form a homodimer.	got7fsn_ti	dimerization activity													molecular_function											owl:Class	
GO:0036296	biolink:NamedThing	response to increased oxygen levels	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.	got7fsn_ti	response to raised oxygen levels				This term should be used when an increase in oxygen levels is not considered a stress response. For a hyperoxic stress response, consider instead 'response to hyperoxia ; GO:0055093.		bf	2012-07-20T01:10:48Z						biological_process											owl:Class	
GO:2001005	biolink:NamedThing	positive regulation of pectin catabolic process	Any process that activates or increases the frequency, rate or extent of pectin catabolic process.	got7fsn_ti	positive regulation of pectin breakdown|positive regulation of pectin catabolism|positive regulation of pectin degradation						tt	2011-08-08T03:24:09Z						biological_process											owl:Class	
GO:0050216	biolink:NamedThing	propanediol-phosphate dehydrogenase activity	Catalysis of the reaction: NAD(+) + propane-1,2-diol 1-phosphate = H(+) + hydroxyacetone phosphate + NADH.	got7fsn_ti												EC:1.1.1.7|KEGG_REACTION:R04236|MetaCyc:PROPANEDIOL-PHOSPHATE-DEHYDROGENASE-RXN|RHEA:21584		molecular_function											owl:Class	
GO:0042968	biolink:NamedThing	homoserine transport	The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0031679	biolink:NamedThing	NADH dehydrogenase (plastoquinone) activity	Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol.	got7fsn_ti	NADH:plastoquinone reductase activity										GO:0030024			molecular_function											owl:Class	
GO:0042051	biolink:NamedThing	compound eye photoreceptor development	The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.	got7fsn_ti	adult eye photoreceptor development													biological_process											owl:Class	
GO:0043396	biolink:NamedThing	corticotropin-releasing hormone secretion	The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle.	got7fsn_ti	CRF secretion|CRH secretion|corticotropin-releasing factor secretion													biological_process											owl:Class	
GO:2000194	biolink:NamedThing	regulation of female gonad development	Any process that modulates the frequency, rate or extent of female gonad development.	got7fsn_ti	regulation of ovarian development|regulation of ovary development						yaf	2010-10-19T10:45:34Z						biological_process											owl:Class	
GO:0046422	biolink:NamedThing	violaxanthin de-epoxidase activity	Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O.	got7fsn_ti	violaxanthin:ascorbate oxidoreductase activity|VDE											RHEA:32371|EC:1.23.5.1		molecular_function											owl:Class	
GO:0005313	biolink:NamedThing	L-glutamate transmembrane transporter activity	Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.	got7fsn_ti	glutamate/aspartate:sodium symporter activity|glutamate/aspartate porter activity|L-glutamate transporter activity											Reactome:R-HSA-5624256|Reactome:R-HSA-428052|Reactome:R-HSA-210444		molecular_function											owl:Class	
GO:0070147	biolink:NamedThing	mitochondrial cysteinyl-tRNA aminoacylation	The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0120166	biolink:NamedThing	protoperithecium formation	The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium.	got7fsn_ti					Note that this term represents protoperithecium formation across homothallic and heterothallic species that do not have the same mechanism.		krc	2018-05-17T17:27:16Z						biological_process											owl:Class	
GO:0042743	biolink:NamedThing	hydrogen peroxide metabolic process	The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	got7fsn_ti	hydrogen peroxide metabolism|H2O2 metabolic process													biological_process											owl:Class	
GO:0002129	biolink:NamedThing	wobble position guanine ribose methylation	The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.	got7fsn_ti														biological_process											owl:Class	
GO:0002938	biolink:NamedThing	tRNA guanine ribose methylation	The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety.	got7fsn_ti							hjd	2012-11-02T15:55:55Z						biological_process											owl:Class	
GO:0018170	biolink:NamedThing	C-terminal peptidyl-polyglutamic acid amidation	The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus.	got7fsn_ti												RESID:AA0261		biological_process											owl:Class	
GO:0051779	biolink:NamedThing	gibberellin 12-aldehyde oxidase activity	Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).	got7fsn_ti	GA12-aldehyde oxidase activity				Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-kaurenoate oxidase activity ; GO:0051777' and 'ent-7-alpha-hydroxykaurenoate oxidase activity ; GO:0051778'.							RHEA:22700|MetaCyc:RXN1F-161		molecular_function											owl:Class	
GO:0061350	biolink:NamedThing	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.	got7fsn_ti							dph	2010-10-01T10:57:33Z						biological_process											owl:Class	
GO:0044720	biolink:NamedThing	negative regulation of imaginal disc-derived wing size	Any process that reduces the size of an imaginal disc-derived wing.	got7fsn_ti							jl	2012-10-18T13:50:49Z						biological_process											owl:Class	
GO:0018749	biolink:NamedThing	(3,5-dichlorophenylurea)acetate amidohydrolase activity	Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine.	got7fsn_ti												UM-BBD_reactionID:r0708		molecular_function											owl:Class	
GO:0070852	biolink:NamedThing	cell body fiber	A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.	got7fsn_ti	cell body fibre|primary neurite						mah	2009-08-11T04:38:53Z						cellular_component											owl:Class	
GO:0015565	biolink:NamedThing	threonine efflux transmembrane transporter activity	Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	threonine efflux permease activity|threonine export protein|threonine export transporter activity													molecular_function											owl:Class	
GO:0034639	biolink:NamedThing	L-amino acid efflux transmembrane transporter activity	Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	L-amino acid export transporter activity|L-amino acid efflux permease activity													molecular_function											owl:Class	
GO:0097491	biolink:NamedThing	sympathetic neuron projection guidance	The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.	got7fsn_ti	sympathetic neuronal cell projection guidance|sympathetic neurite guidance|sympathetic neuron protrusion guidance|sympathetic neuron process guidance						pr	2013-07-10T11:49:21Z						biological_process											owl:Class	
GO:0015932	biolink:NamedThing	nucleobase-containing compound transmembrane transporter activity	Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.	got7fsn_ti	nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity													molecular_function											owl:Class	
GO:0018462	biolink:NamedThing	4-(hydroxymethyl)benzenesulfonate dehydrogenase activity	Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH.	got7fsn_ti	4-sulfobenzyl alcohol dehydrogenase activity|4-(hydroxymethyl)benzenesulphonate dehydrogenase activity|4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase activity											EC:1.1.1.257|UM-BBD_reactionID:r0291|RHEA:24412|KEGG_REACTION:R05271|MetaCyc:1.1.1.257-RXN		molecular_function											owl:Class	
GO:0045851	biolink:NamedThing	pH reduction	Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.	got7fsn_ti	acidification													biological_process											owl:Class	
GO:0019800	biolink:NamedThing	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.	got7fsn_ti	peptide cross-linking via chondroitin 4-sulphate glycosaminoglycan											RESID:AA0219		biological_process											owl:Class	
GO:0047983	biolink:NamedThing	homoglutathione synthase activity	Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H(+) + phosphate.	got7fsn_ti	beta-alanine specific hGSH synthetase activity|homoglutathione synthetase activity|gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming)											EC:6.3.2.23|MetaCyc:HOMOGLUTATHIONE-SYNTHASE-RXN|RHEA:17993|KEGG_REACTION:R02741		molecular_function											owl:Class	
GO:0090282	biolink:NamedThing	positive regulation of transcription involved in G2/M transition of mitotic cell cycle	Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle|positive regulation of G2/M-specific transcription in the mitotic cell cycle|up-regulation of transcription involved in G2/M transition of mitotic cell cycle|activation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle|up-regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle|up-regulation of G2/M-specific transcription in the mitotic cell cycle|activation of G2/M-specific transcription in the mitotic cell cycle|activation of transcription involved in G2/M transition of mitotic cell cycle						tb	2010-02-09T02:13:26Z						biological_process											owl:Class	
GO:0043810	biolink:NamedThing	ornithine-acyl [acyl carrier protein] N-acyltransferase activity	Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids.	got7fsn_ti	L-ornithine N(alpha)-acyltransferase|ornithine-acyl[acyl carrier protein] N-acyltransferase activity											RHEA:20633|EC:2.3.2.30		molecular_function											owl:Class	
GO:0097020	biolink:NamedThing	COPII receptor activity	Binding specifically to a substance (cargo) to deliver it to a COPII transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20002					pr	2011-03-24T04:19:55Z						molecular_function											owl:Class	
GO:1990342	biolink:NamedThing	heterochromatin island	A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/11247			An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin islands are formed at meiotic genes during vegetative (mitotic) growth.		mah	2014-03-21T15:26:44Z						cellular_component											owl:Class	
GO:0021930	biolink:NamedThing	cerebellar granule cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0009835	biolink:NamedThing	fruit ripening	An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.	got7fsn_ti	fruit senescence|fruit maturation											Wikipedia:Ripening		biological_process											owl:Class	
GO:0014732	biolink:NamedThing	skeletal muscle atrophy	A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.	got7fsn_ti														biological_process											owl:Class	
GO:0016403	biolink:NamedThing	dimethylargininase activity	Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.	got7fsn_ti	NG,NG-dimethyl-L-arginine dimethylamidohydrolase activity|NG,NG-dimethylarginine dimethylaminohydrolase activity|dimethylarginine dimethylaminohydrolase activity|N(G),N(G)-dimethylarginine dimethylaminohydrolase activity											Reactome:R-HSA-5693373|MetaCyc:DIMETHYLARGININASE-RXN|EC:3.5.3.18|RHEA:17305		molecular_function											owl:Class	
GO:0065005	biolink:NamedThing	protein-lipid complex assembly	The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.	got7fsn_ti														biological_process											owl:Class	
GO:0003844	biolink:NamedThing	1,4-alpha-glucan branching enzyme activity	Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.	got7fsn_ti	1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase activity|alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase activity|branching enzyme activity|branching glycosyltransferase activity|amylose isomerase activity|amylo-(1,4 to 1,6)transglucosidase activity|amylo-(1,4->1,6)-transglycosylase activity|enzymatic branching factor|glycogen branching enzyme activity|Q-enzyme|glucosan transglycosylase activity|enzyme Q|starch branching enzyme|alpha-glucan-branching glycosyltransferase activity|1,4-glucan-6-(1,4-glucano)-transferase activity|plant branching enzyme											Reactome:R-HSA-3878762|Reactome:R-HSA-3322016|Reactome:R-HSA-3322057|Reactome:R-HSA-3322005|MetaCyc:GLYCOGEN-BRANCH-RXN|EC:2.4.1.18		molecular_function											owl:Class	
GO:0072137	biolink:NamedThing	condensed mesenchymal cell proliferation	The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.	got7fsn_ti							mah	2010-02-22T02:38:54Z						biological_process											owl:Class	
GO:0018569	biolink:NamedThing	hydroquinone 1,2-dioxygenase activity	Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde.	got7fsn_ti												UM-BBD_reactionID:r0228|EC:1.13.11.-		molecular_function											owl:Class	
GO:0090016	biolink:NamedThing	regulation of leaflet formation	Any process that modulates the frequency, rate or extent of leaflet formation.	got7fsn_ti							tb	2009-07-29T11:23:48Z						biological_process											owl:Class	
GO:0000444	biolink:NamedThing	MIS12/MIND type complex	A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.	got7fsn_ti	Mis12 complex													cellular_component											owl:Class	
GO:0046134	biolink:NamedThing	pyrimidine nucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	got7fsn_ti	pyrimidine nucleoside formation|pyrimidine nucleoside synthesis|pyrimidine nucleoside biosynthesis|pyrimidine nucleoside anabolism													biological_process											owl:Class	
GO:0010782	biolink:NamedThing	proboscis morphogenesis, labial disc-derived	The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0042366	biolink:NamedThing	cobalamin catabolic process	The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	got7fsn_ti	vitamin B12 catabolism|cobalamin breakdown|cobalamin catabolism|cobalamin degradation|vitamin B12 catabolic process													biological_process											owl:Class	
GO:0007041	biolink:NamedThing	lysosomal transport	The directed movement of substances into, out of or within a lysosome.	got7fsn_ti														biological_process											owl:Class	
GO:0003120	biolink:NamedThing	regulation of vasoconstriction by circulating epinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream.	got7fsn_ti	regulation of vasoconstriction by circulating adrenaline													biological_process											owl:Class	
GO:0034686	biolink:NamedThing	integrin alphav-beta8 complex	An integrin complex that comprises one alphav subunit and one beta8 subunit.	got7fsn_ti	alphav-beta8 integrin complex|ITGAV-ITGB8 complex													cellular_component											owl:Class	
GO:0102357	biolink:NamedThing	mithramycin dehydrogenase activity	Catalysis of the reaction: mithramycin + NADP <=> mithramycin DK + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13385		molecular_function											owl:Class	
GO:0070535	biolink:NamedThing	histone H2A K63-linked ubiquitination	A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.	got7fsn_ti														biological_process											owl:Class	
GO:0070534	biolink:NamedThing	protein K63-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.	got7fsn_ti	protein K63-linked polyubiquitination													biological_process											owl:Class	
GO:0034963	biolink:NamedThing	box C/D RNA processing	Any process involved in the conversion of a primary box C/D type small  RNA transcript into a mature box C/D RNA.	got7fsn_ti	box C/D sRNA processing|box C/D snoRNA processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0031612	biolink:NamedThing	cytosolic proteasome regulatory particle, base subcomplex	The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0001116	biolink:NamedThing	protein-DNA-RNA complex assembly	The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex.	got7fsn_ti							krc	2010-12-03T04:01:38Z						biological_process											owl:Class	
GO:0001115	biolink:NamedThing	protein-DNA-RNA complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex.	got7fsn_ti	protein-DNA-RNA complex subunit organisation						krc	2010-12-03T04:00:02Z						biological_process											owl:Class	
GO:0061646	biolink:NamedThing	positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization	Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter.	got7fsn_ti							dph	2014-10-02T14:18:49Z						biological_process											owl:Class	
GO:0071144	biolink:NamedThing	heteromeric SMAD protein complex	A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric.	got7fsn_ti	SMAD2-SMAD3-SMAD4 protein complex|SMAD3-SMAD4 protein complex|SMAD1-SMAD4 protein complex|SMAD2-SMAD4 protein complex							2009-11-16T02:44:37Z			GO:0071145|GO:0071146			cellular_component											owl:Class	
GO:0072344	biolink:NamedThing	rescue of stalled ribosome	A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.	got7fsn_ti							mah	2010-11-10T11:54:26Z						biological_process											owl:Class	
GO:0102294	biolink:NamedThing	cholesterol dehydrogenase activity	Catalysis of the reaction: cholesterol + NAD = cholest-5-en-3-one + NADH + H+.	got7fsn_ti												MetaCyc:RXN-12693|RHEA:35459|EC:1.1.1.145		molecular_function											owl:Class	
GO:0016875	biolink:NamedThing	ligase activity, forming carbon-oxygen bonds	Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti												EC:6.1.-.-		molecular_function											owl:Class	
GO:0043995	biolink:NamedThing	histone acetyltransferase activity (H4-K5 specific)	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).	got7fsn_ti	histone lysine N-acetyltransferase activity (H4-K5 specific)													molecular_function											owl:Class	
GO:0048911	biolink:NamedThing	efferent axon development in anterior lateral line nerve	The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0018935	biolink:NamedThing	aerobic nitrilotriacetate metabolic process	The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen.	got7fsn_ti	aerobic nitrilotriacetate metabolism													biological_process											owl:Class	
GO:0072316	biolink:NamedThing	alpha-glucan catabolic process involved in ascospore release from ascus	The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus.	got7fsn_ti	alpha-glucan catabolism involved in ascospore release from ascus|alpha-glucan degradation involved in ascospore release from ascus|alpha-glucan breakdown involved in ascospore release from ascus						mah	2010-10-25T05:43:52Z						biological_process											owl:Class	
GO:0072000	biolink:NamedThing	extracellular polysaccharide catabolic process involved in ascospore release from ascus	The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus.	got7fsn_ti	extracellular polysaccharide degradation involved in ascospore release from ascus|ascus endolysis|extracellular polysaccharide catabolism involved in ascospore release from ascus|ascus catabolic process|extracellular polysaccharide breakdown involved in ascospore release from ascus						mah	2010-10-25T05:30:41Z						biological_process											owl:Class	
GO:0032798	biolink:NamedThing	Swi5-Sfr1 complex	A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces).	got7fsn_ti	Swi5 complex|Sae3-Mei5 complex				Note that this term refers to Schizosaccharomyces pombe Swi5, which should not be confused with the unrelated Saccharomyces Swi5p.									cellular_component											owl:Class	
GO:0018757	biolink:NamedThing	deisopropylhydroxyatrazine aminohydrolase activity	Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine.	got7fsn_ti												UM-BBD_reactionID:r0121|KEGG_REACTION:R05574		molecular_function											owl:Class	
GO:0047471	biolink:NamedThing	maltose alpha-D-glucosyltransferase activity	Catalysis of the reaction: maltose = trehalose.	got7fsn_ti	trehalose synthase activity|maltose glucosylmutase activity|maltose alpha-D-glucosylmutase activity											EC:5.4.99.16|MetaCyc:5.4.99.16-RXN|RHEA:15145		molecular_function											owl:Class	
GO:0102992	biolink:NamedThing	2-methylbutyronitrile hydroxylase activity	Catalysis of the reaction: H+ + 2-methylbutyronitrile + NADPH + O2 <=> H2O + NADP + 2-hydroxy-2-methylbutyronitrile.	got7fsn_ti												RHEA:51948|MetaCyc:RXN-9642		molecular_function											owl:Class	
GO:0006283	biolink:NamedThing	transcription-coupled nucleotide-excision repair	The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.	got7fsn_ti	transcription-coupled NER|transcription-coupled repair|TC-NER|TCR													biological_process											owl:Class	
GO:0032219	biolink:NamedThing	cell wall macromolecule catabolic process involved in cytogamy	The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy.	got7fsn_ti	cell wall macromolecule catabolic process during cytogamy													biological_process											owl:Class	
GO:0102093	biolink:NamedThing	acrylate:acyl-coA CoA transferase activity	Catalysis of the reaction: acryloyl-CoA + H2O <=> acrylate + coenzyme A + H+.	got7fsn_ti												MetaCyc:RXN-10985		molecular_function											owl:Class	
GO:0035385	biolink:NamedThing	Roundabout signaling pathway	A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	Roundabout signalling pathway|ROBO signaling pathway|ROBO/SLIT signaling pathway						bf	2010-03-18T02:38:31Z						biological_process											owl:Class	
GO:0051502	biolink:NamedThing	diterpene phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses.	got7fsn_ti	diterpene phytoalexin formation|diterpene phytoalexin biosynthesis|diterpene phytoalexin anabolism|diterpene phytoalexin synthesis													biological_process											owl:Class	
GO:0033068	biolink:NamedThing	macrolide biosynthetic process	The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.	got7fsn_ti	macrolide biosynthesis|macrolide anabolism|macrolide formation|macrolide synthesis													biological_process											owl:Class	
GO:0052634	biolink:NamedThing	C-19 gibberellin 2-beta-dioxygenase activity	Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons.	got7fsn_ti	C-19 gibberellin 2-beta-hydroxylase activity|C-19 gibberellin 2-oxidase activity|C-19 gibberellin 2beta-hydroxylase activity|C-19 GA 2-oxidase activity|(C-19 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|C-19 gibberellin 2beta-dioxygenase activity|C(19) gibberellin 2-oxidase activity											EC:1.14.11.13		molecular_function											owl:Class	
GO:0102119	biolink:NamedThing	gibberellin A20 carboxyl methyltransferase activity	Catalysis of the reaction: gibberellin A20 + S-adenosyl-L-methionine  <=> gibberellin A20 methyl ester + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-11360		molecular_function											owl:Class	
GO:0071201	biolink:NamedThing	Kv4.3-DPP6 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3.	got7fsn_ti	Kv4.3-DPPX channel complex						mah	2009-11-23T05:20:54Z				CORUM:599		cellular_component											owl:Class	
GO:0044516	biolink:NamedThing	positive regulation of glucagon-like peptide receptor 1 activity in other organism	A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism.	got7fsn_ti							jl	2012-02-26T11:09:44Z						biological_process											owl:Class	
GO:0016259	biolink:NamedThing	selenocysteine metabolic process	The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins.	got7fsn_ti	selenocysteine metabolism													biological_process											owl:Class	
GO:0047430	biolink:NamedThing	oligosaccharide-diphosphodolichol diphosphatase activity	Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate.	got7fsn_ti	oligosaccharide-diphosphodolichol phosphodolichohydrolase activity|oligosaccharide-diphosphodolichol pyrophosphatase activity											MetaCyc:3.6.1.44-RXN|RHEA:15205|EC:3.6.1.44		molecular_function											owl:Class	
GO:0030746	biolink:NamedThing	isoflavone 4'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.	got7fsn_ti	isoflavone methyltransferase activity|4'-hydroxyisoflavone methyltransferase activity|isoflavone O-methyltransferase activity|S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase activity											RHEA:31739|EC:2.1.1.46|MetaCyc:ISOFLAVONE-4-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0032843	biolink:NamedThing	hydroperoxide reductase activity	Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.	got7fsn_ti														molecular_function											owl:Class	
GO:0140665	biolink:NamedThing	ATP-dependent H3-H4 histone complex loader activity	Loading of a histone H3-H4 complex onto DNA, driven by ATP hydrolysis.	got7fsn_ti	H3-H4 dimer loading activity|H3-H4 histone complex loader activity|histone H3-H4 dimer loading activity|histone chaperone|H3-H4 histone chaperone	https://github.com/geneontology/go-ontology/issues/21733|https://github.com/geneontology/go-ontology/issues/21580					pg	2021-06-22T13:57:16Z						molecular_function											owl:Class	
GO:0140674	biolink:NamedThing	ATP-dependent histone loader activity	Depositing a histone or a histone complex onto DNA.	got7fsn_ti	histone loader activity|histone loading activity	https://github.com/geneontology/go-ontology/issues/21733					pg	2021-06-29T12:42:57Z						molecular_function											owl:Class	
GO:0052747	biolink:NamedThing	sinapyl alcohol dehydrogenase activity	Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+.	got7fsn_ti	sinapyl-alcohol:NADP+ oxidoreductase activity|sinapyl-alcohol dehydrogenase activity							2011-09-21T12:42:06Z				MetaCyc:RXN-1125|EC:1.1.1.195|RHEA:45704|KEGG_REACTION:R03918		molecular_function											owl:Class	
GO:0000254	biolink:NamedThing	C-4 methylsterol oxidase activity	Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O.	got7fsn_ti	4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating)|methylsterol monooxygenase activity|methylsterol hydroxylase activity|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|4-methylsterol oxidase activity				Note that zymosterol is cholesta-8,24-dien-3-ol.							RHEA:55220|Reactome:R-HSA-194641|EC:1.14.18.9|MetaCyc:1.14.13.72-RXN|Reactome:R-HSA-194669		molecular_function											owl:Class	
GO:0030283	biolink:NamedThing	testosterone dehydrogenase [NAD(P)] activity	Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+.	got7fsn_ti	17beta-hydroxy steroid dehydrogenase|beta-hydroxy steroid dehydrogenase|3beta-hydroxysteroid dehydrogenase|3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase|3(or 17)beta-hydroxysteroid dehydrogenase activity|3beta-hydroxy steroid dehydrogenase											MetaCyc:1.1.1.51-RXN|Reactome:R-HSA-193064|EC:1.1.1.51		molecular_function											owl:Class	
GO:0008772	biolink:NamedThing	[isocitrate dehydrogenase (NADP+)] kinase activity	Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate.	got7fsn_ti	IDH-K/P|IDHK/P|isocitrate dehydrogenase (NADP+) kinase activity|ICDH kinase/phosphatase activity|ATP:isocitrate dehydrogenase (NADP+) phosphotransferase activity|isocitrate dehydrogenase kinase (phosphorylating) activity|isocitrate dehydrogenase kinase/phosphatase activity|isocitrate dehydrogenase (NADP) kinase activity|isocitrate dehydrogenase kinase activity|IDH kinase/phosphatase activity|IDH kinase activity											RHEA:43540|MetaCyc:PHOSICITDEHASE-RXN|EC:2.7.11.5		molecular_function											owl:Class	
GO:0044566	biolink:NamedThing	chondrocyte activation	A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti							jl	2012-04-05T04:45:38Z						biological_process											owl:Class	
GO:0004456	biolink:NamedThing	phosphogluconate dehydratase activity	Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O.	got7fsn_ti	gluconate 6-phosphate dehydratase activity|6-phosphogluconate dehydratase activity|6-phosphogluconic dehydrase activity|gluconate-6-phosphate dehydratase activity|6-phosphogluconate dehydrase activity|6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)|6-phospho-D-gluconate hydro-lyase activity											RHEA:17277|EC:4.2.1.12|MetaCyc:PGLUCONDEHYDRAT-RXN|KEGG_REACTION:R02036		molecular_function											owl:Class	
GO:1900798	biolink:NamedThing	cordyol C catabolic process	The chemical reactions and pathways resulting in the breakdown of cordyol C.	got7fsn_ti	cordyol C degradation|cordyol C catabolism|cordyol C breakdown						di	2012-06-04T09:48:10Z						biological_process											owl:Class	
GO:0019154	biolink:NamedThing	glycolate dehydrogenase activity	Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate.	got7fsn_ti	glycolate:acceptor 2-oxidoreductase activity|glycolic acid dehydrogenase activity|glycolate oxidoreductase activity|glycolate:(acceptor) 2-oxidoreductase activity											RHEA:21264|EC:1.1.99.14|MetaCyc:GLYCOLATEDEHYDRO-RXN|KEGG_REACTION:R00476		molecular_function											owl:Class	
GO:0050610	biolink:NamedThing	methylarsonate reductase activity	Catalysis of the reaction: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H(2)O + methylarsonous acid.	got7fsn_ti	glutathione:methylarsonate oxidoreductase activity|MMA(V) reductase activity											RHEA:15969|KEGG_REACTION:R05748|MetaCyc:1.20.4.2-RXN|Reactome:R-HSA-5696230|EC:1.20.4.2|UM-BBD_reactionID:r0837		molecular_function											owl:Class	
GO:0102760	biolink:NamedThing	6-deoxocathasterone hydroxylase activity	Catalysis of the reaction: 6-deoxycathasterone + O2 + a reduced electron acceptor <=> 6-deoxoteasterone + H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-774		molecular_function											owl:Class	
GO:0002476	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0035946	biolink:NamedThing	mitochondrial mRNA surveillance	The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion.	got7fsn_ti	mitochondrial aberrant RNA catabolic process|mitochondrial mRNA quality control|mitochondrial messenger RNA surveillance						bf	2011-07-28T10:37:07Z						biological_process											owl:Class	
GO:0034952	biolink:NamedThing	malonate semialdehyde decarboxylase activity	Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2.	got7fsn_ti												UM-BBD_reactionID:r0266		molecular_function											owl:Class	
GO:0008663	biolink:NamedThing	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity	Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.	got7fsn_ti	cyclic phosphodiesterase:3'-nucleotidase activity|cyclic 2',3'-nucleotide 2'-phosphodiesterase activity|nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase activity|ribonucleoside 2',3'-cyclic phosphate diesterase activity|2',3 '-cyclic AMP phosphodiesterase activity|2',3'-cyclic AMP 2'-phosphohydrolase activity|2':3'-cyclic phosphodiesterase activity|cyclic 2',3'-nucleotide phosphodiesterase|2',3'-cyclic nucleoside monophosphate phosphodiesterase|2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase activity|2',3'-cyclic nucleotide phosphohydrolase|2',3'-cyclic nucleotidase activity											EC:3.1.4.16|MetaCyc:CYCPHOSDIESTER-RXN|RHEA:19621		molecular_function											owl:Class	
GO:0016027	biolink:NamedThing	inaD signaling complex	A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD.	got7fsn_ti	inaD signalling complex													cellular_component											owl:Class	
GO:0008879	biolink:NamedThing	glucose-1-phosphate thymidylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose.	got7fsn_ti	dTDP-glucose pyrophosphorylase activity|glucose 1-phosphate thymidylyltransferase activity|TDP-glucose pyrophosphorylase activity|dTDP-glucose synthase activity|thymidine diphosphoglucose pyrophosphorylase activity|dTDP-glucose diphosphorylase activity|dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase activity|thymidine diphosphate glucose pyrophosphorylase activity											EC:2.7.7.24|RHEA:15225|KEGG_REACTION:R02328|MetaCyc:DTDPGLUCOSEPP-RXN		molecular_function											owl:Class	
GO:0033920	biolink:NamedThing	6-phospho-beta-galactosidase activity	Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.	got7fsn_ti	phospho-beta-D-galactosidase activity|beta-D-phosphogalactoside galactohydrolase activity|6-phospho-beta-D-galactoside 6-phosphogalactohydrolase activity|6-phospho-beta-D-galactosidase activity|phospho-beta-galactosidase activity											RHEA:24568|MetaCyc:6-PHOSPHO-BETA-GALACTOSIDASE-RXN|EC:3.2.1.85		molecular_function											owl:Class	
GO:0008537	biolink:NamedThing	proteasome activator complex	A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex.	got7fsn_ti	PA28													cellular_component											owl:Class	
GO:0005900	biolink:NamedThing	oncostatin-M receptor complex	A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.	got7fsn_ti														cellular_component											owl:Class	
GO:0000110	biolink:NamedThing	nucleotide-excision repair factor 1 complex	One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively.	got7fsn_ti	XPA-ERCC1-ERCC4 complex|NEF1 complex				Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.									cellular_component											owl:Class	
GO:0038145	biolink:NamedThing	macrophage colony-stimulating factor signaling pathway	A series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	macrophage colony-stimulating factor signalling pathway|M-CSF signaling pathway						bf	2012-04-27T11:04:18Z						biological_process											owl:Class	
GO:0008790	biolink:NamedThing	arabinose isomerase activity	Catalysis of the reaction: D-arabinose = D-ribulose.	got7fsn_ti	D-arabinose ketol-isomerase activity|D-arabinose(L-fucose) isomerase activity|D-arabinose aldose-ketose-isomerase activity|D-arabinose isomerase activity											MetaCyc:DARABISOM-RXN|EC:5.3.1.3|RHEA:13849		molecular_function											owl:Class	
GO:0018227	biolink:NamedThing	peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine.	got7fsn_ti	peptidyl-S-12-hydroxyfarnesyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-12-hydroxyfarnesyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-12-hydroxyfarnesyl-L-cysteine synthesis from peptidyl-cysteine											RESID:AA0103		biological_process											owl:Class	
GO:0004073	biolink:NamedThing	aspartate-semialdehyde dehydrogenase activity	Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH.	got7fsn_ti	ASA dehydrogenase activity|L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)|L-aspartate-beta-semialdehyde dehydrogenase activity|aspartic beta-semialdehyde dehydrogenase activity|L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating)|aspartic semialdehyde dehydrogenase activity|aspartate semialdehyde dehydrogenase activity											RHEA:24284|MetaCyc:ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|KEGG_REACTION:R02291|EC:1.2.1.11		molecular_function											owl:Class	
GO:0002069	biolink:NamedThing	columnar/cuboidal epithelial cell maturation	The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.	got7fsn_ti														biological_process											owl:Class	
GO:0051712	biolink:NamedThing	positive regulation of killing of cells of other organism	Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism.	got7fsn_ti	upregulation of killing of cells of another organism|induction by organism of apoptosis in other organism involved in symbiotic interaction|induction by organism of apoptosis in other organism during symbiotic interaction|enhancement of other organism programmed cell death by organism|stimulation of killing of cells of another organism|positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction|activation of killing of cells of another organism|up-regulation of killing of cells of another organism|up regulation of killing of cells of another organism|activation by organism of apoptotic programmed cell death in other organism during symbiotic interaction|positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/20287									GO:0052529|GO:0052518|GO:0052330|GO:0052388|GO:0052501			biological_process											owl:Class	
GO:0043068	biolink:NamedThing	positive regulation of programmed cell death	Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.	got7fsn_ti	activation of programmed cell death|stimulation of programmed cell death|upregulation of programmed cell death|positive regulation of non-apoptotic programmed cell death|up-regulation of programmed cell death|up regulation of programmed cell death										GO:0043071			biological_process											owl:Class	
GO:0006527	biolink:NamedThing	arginine catabolic process	The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.	got7fsn_ti	arginine degradation|arginine catabolism|arginine breakdown													biological_process											owl:Class	
GO:0102530	biolink:NamedThing	aclacinomycin T methylesterase activity	Catalysis of the reaction: aclacinomycin T(1+) + H2O <=> 15-demethylaclacinomycin T  + methanol + H+.	got7fsn_ti												MetaCyc:RXN-14703|EC:3.1.1.95|RHEA:37891		molecular_function											owl:Class	
GO:0019422	biolink:NamedThing	disproportionation of elemental sulfur	The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2.	got7fsn_ti	disproportionation of elemental sulphur											MetaCyc:P203-PWY		biological_process											owl:Class	
GO:0005879	biolink:NamedThing	axonemal microtubule	A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.	got7fsn_ti														cellular_component											owl:Class	
GO:0018317	biolink:NamedThing	protein C-linked glycosylation via tryptophan	The glycosylation of a carbon atom of a peptidyl-tryptophan residue.	got7fsn_ti	protein amino acid C-linked glycosylation via tryptophan													biological_process											owl:Class	
GO:0047668	biolink:NamedThing	amygdalin beta-glucosidase activity	Catalysis of the reaction: (R)-amygdalin + H(2)O = (R)-prunasin + D-glucose.	got7fsn_ti	amygdalinase|amygdalin beta-D-glucohydrolase activity|amygdalin b-glucosidase activity|amygdalin hydrolase activity|(R)-amygdalin beta-glucosidase activity|amygdalin glucosidase activity										GO:0080080	KEGG_REACTION:R02985|EC:3.2.1.117|MetaCyc:AMYGDALIN-BETA-GLUCOSIDASE-RXN|RHEA:14177		molecular_function											owl:Class	
GO:0031958	biolink:NamedThing	corticosteroid receptor signaling pathway	Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor.	got7fsn_ti	corticosteroid receptor signalling pathway													biological_process											owl:Class	
GO:0102849	biolink:NamedThing	1-18:2-2-18:3-digalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-18:3-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8314|EC:1.14.19.35		molecular_function											owl:Class	
GO:0140462	biolink:NamedThing	pericentric heterochromatin organization	The organization of chromatin into heterochromatin at the pericentric region of a chromosome.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19396					pg	2020-05-06T07:47:09Z						biological_process											owl:Class	
GO:0034272	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class III, type II	A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.	got7fsn_ti	PtdIns-3-kinase complex II|phosphatidylinositol 3-kinase complex II				Note that this term should not be confused with '1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; GO:0005943' or '1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex ; GO:0005944'.									cellular_component											owl:Class	
GO:0000838	biolink:NamedThing	Hrd1p ubiquitin ligase ERAD-M complex	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.	got7fsn_ti														cellular_component											owl:Class	
GO:0001780	biolink:NamedThing	neutrophil homeostasis	The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti					Note that this term represents the return of neutrophil levels to stable numbers following an immune response as well as the proliferation and elimination of neutrophils required to maintain stable numbers in the absence of an outside stimulus.									biological_process											owl:Class	
GO:0031847	biolink:NamedThing	type 1 neurotensin receptor binding	Binding to a type 1 neurotensin receptor.	got7fsn_ti	type 1 neurotensin receptor ligand													molecular_function											owl:Class	
GO:0031846	biolink:NamedThing	neurotensin receptor binding	Binding to a neurotensin receptor.	got7fsn_ti	neurotensin receptor ligand													molecular_function											owl:Class	
GO:0021845	biolink:NamedThing	neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration	The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.	got7fsn_ti														biological_process											owl:Class	
GO:0038141	biolink:NamedThing	ERBB4-ERBB4 complex	A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4).	got7fsn_ti	ERBB4 homodimer						bf	2012-03-30T02:06:20Z						cellular_component											owl:Class	
GO:0018681	biolink:NamedThing	deisopropylatrazine monooxygenase activity	Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine.	got7fsn_ti												EC:1.14.15.-|KEGG_REACTION:R05567		molecular_function											owl:Class	
GO:0103032	biolink:NamedThing	tartronate semialdehyde reductase activity	Catalysis of the reaction: D-glycerate + NAD <=> H+ + 2-hydroxy-3-oxopropanoate + NADH.	got7fsn_ti												RHEA:18845|MetaCyc:RXN0-5289		molecular_function											owl:Class	
GO:0000244	biolink:NamedThing	spliceosomal tri-snRNP complex assembly	The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.	got7fsn_ti	assembly of spliceosomal tri-snRNP|spliceosomal tri-snRNP assembly|spliceosomal tri-snRNP U4atac/U6atac.U5 assembly|assembly of spliceosomal tri-snRNP U4atac/U6atac.U5|spliceosomal tri-snRNP U4/U6.U5 assembly|snRNP recycling|assembly of spliceosomal tri-snRNP U4/U6.U5										GO:0000351|GO:0000355			biological_process											owl:Class	
GO:0035158	biolink:NamedThing	regulation of tube diameter, open tracheal system	Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.	got7fsn_ti	regulation of tracheal tube diameter|tracheal tube expansion|tracheal tube dilation													biological_process											owl:Class	
GO:0035296	biolink:NamedThing	regulation of tube diameter	Any process that modulates the diameter of a tube.	got7fsn_ti														biological_process											owl:Class	
GO:0051039	biolink:NamedThing	positive regulation of transcription involved in meiotic cell cycle	Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle.	got7fsn_ti	positive regulation of meiotic transcription|upregulation of transcription during meiosis|up regulation of transcription during meiosis|up-regulation of transcription during meiosis|activation of transcription during meiosis|stimulation of transcription during meiosis|positive regulation of transcription, meiotic													biological_process											owl:Class	
GO:0019153	biolink:NamedThing	protein-disulfide reductase (glutathione) activity	Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol.	got7fsn_ti	protein disulfide reductase (glutathione)|insulin reductase activity|thiol-protein disulphide oxidoreductase activity|glutathione-insulin transhydrogenase activity|glutaredoxin reductase|protein disulfide transhydrogenase activity|protein-disulfide isomerase/oxidoreductase activity|reductase, protein disulfide (glutathione)|protein-disulfide interchange enzyme|glutathione-protein disulfide oxidoreductase activity|protein-disulphide reductase (glutathione) activity|glutathione--insulin transhydrogenase activity|GSH-insulin transhydrogenase activity|glutathione:protein-disulfide oxidoreductase activity|thiol:protein-disulfide oxidoreductase activity											EC:1.8.4.2|MetaCyc:PRODISULFREDUCT-RXN|RHEA:21064		molecular_function											owl:Class	
GO:0046547	biolink:NamedThing	trans-aconitate 3-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine.	got7fsn_ti	S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 3'-O-methyltransferase activity											EC:2.1.1.145|RHEA:22200|MetaCyc:2.1.1.145-RXN|KEGG_REACTION:R05764		molecular_function											owl:Class	
GO:0102964	biolink:NamedThing	S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity	Catalysis of the reaction: (S)-corytuberine + S-adenosyl-L-methionine  <=> H+ + magnoflorine + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:51524|MetaCyc:RXN-9315		molecular_function											owl:Class	
GO:0034625	biolink:NamedThing	fatty acid elongation, monounsaturated fatty acid	Elongation of a fatty acid chain into which one C-C double bond has been introduced.	got7fsn_ti														biological_process											owl:Class	
GO:0016333	biolink:NamedThing	morphogenesis of follicular epithelium	The process in which the anatomical structures of a follicular epithelium are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0050998	biolink:NamedThing	nitric-oxide synthase binding	Binding to nitric-oxide synthase.	got7fsn_ti	NOS binding													molecular_function											owl:Class	
GO:0044318	biolink:NamedThing	L-aspartate:fumarate oxidoreductase activity	Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate.	got7fsn_ti					This is based on the finding that L-aspartate oxidase (NadB) of E. coli preferentially uses fumarate as the electron acceptor and does so under anaerobic conditions. The same enzyme uses oxygen as the electron acceptor under aerobic conditions. The EC conflates the two reactions in EC:1.4.3.16 (as they are catalyzed by the same enzyme).		jl	2010-07-14T01:50:01Z				EC:1.4.3.16		molecular_function											owl:Class	
GO:0004937	biolink:NamedThing	alpha1-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein.	got7fsn_ti	alpha1 adrenoceptor													molecular_function											owl:Class	
GO:0061654	biolink:NamedThing	NEDD8 conjugating enzyme activity	Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y -> Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue.	got7fsn_ti	E2						dph	2014-11-06T13:27:56Z						molecular_function											owl:Class	
GO:0010275	biolink:NamedThing	NAD(P)H dehydrogenase complex assembly	The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool.	got7fsn_ti	NAD(P)H dehydrogenase complex (plastoquinone) assembly													biological_process											owl:Class	
GO:0033415	biolink:NamedThing	UGA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UGA codon.	got7fsn_ti	TGA codon-amino acid adaptor activity				Note that in the standard genetic code, TGA is a stop codon (opal) and is not normally read by a tRNA.									molecular_function											owl:Class	
GO:0006430	biolink:NamedThing	lysyl-tRNA aminoacylation	The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0102733	biolink:NamedThing	typhasterol C-23 hydroxylase activity	Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-719		molecular_function											owl:Class	
GO:0033316	biolink:NamedThing	meiotic spindle assembly checkpoint signaling	A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle.	got7fsn_ti	signal transduction involved in meiotic spindle assembly checkpoint|meiotic spindle assembly checkpoint	https://github.com/geneontology/go-ontology/issues/20935									GO:0072465			biological_process											owl:Class	
GO:0044779	biolink:NamedThing	meiotic spindle checkpoint signaling	A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle.	got7fsn_ti	intracellular signaling pathway involved in meiotic spindle checkpoint|intracellular signal transduction pathway involved in meiotic spindle checkpoint|intracellular signaling cascade involved in meiotic spindle checkpoint|intracellular signal transduction involved in meiotic spindle checkpoint|meiotic spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20935					jl	2013-03-21T14:01:28Z			GO:1902398			biological_process											owl:Class	
GO:0052078	biolink:NamedThing	suppression by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	downregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|down-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|suppression by organism of defense-related host MAP kinase-mediated signal transduction pathway|inhibition by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related host MAPK-mediated signal transduction pathway|negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway|down regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	https://github.com/geneontology/go-ontology/issues/19235									GO:0052275			biological_process											owl:Class	
GO:0120204	biolink:NamedThing	methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity	Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2.	got7fsn_ti							krc	2019-05-10T15:58:47Z						molecular_function											owl:Class	
GO:0061248	biolink:NamedThing	mesonephric glomerulus vasculature morphogenesis	The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.	got7fsn_ti							dph	2010-08-30T01:11:34Z						biological_process											owl:Class	
GO:0072103	biolink:NamedThing	glomerulus vasculature morphogenesis	The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.	got7fsn_ti							mah	2010-02-10T02:34:54Z						biological_process											owl:Class	
GO:0047086	biolink:NamedThing	ketosteroid monooxygenase activity	Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate.	got7fsn_ti	steroid-ketone monooxygenase activity|progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)|ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)|17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)|androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)											MetaCyc:1.14.13.54-RXN|EC:1.14.13.54		molecular_function											owl:Class	
GO:0045921	biolink:NamedThing	positive regulation of exocytosis	Any process that activates or increases the frequency, rate or extent of exocytosis.	got7fsn_ti	upregulation of exocytosis|activation of exocytosis|stimulation of exocytosis|up-regulation of exocytosis|up regulation of exocytosis													biological_process											owl:Class	
GO:0014820	biolink:NamedThing	tonic smooth muscle contraction	A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0102655	biolink:NamedThing	1-18:1-2-trans-16:1-phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:1-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-1726|EC:1.14.19.23		molecular_function											owl:Class	
GO:0097385	biolink:NamedThing	programmed necrotic cell death in response to starvation	A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment).	got7fsn_ti	necrotic cell death in response to starvation						pr	2012-10-22T09:02:18Z						biological_process											owl:Class	
GO:0001842	biolink:NamedThing	neural fold formation	The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.	got7fsn_ti	neural groove formation													biological_process											owl:Class	
GO:0047128	biolink:NamedThing	1,2-dehydroreticulinium reductase (NADPH) activity	Catalysis of the reaction: (R)-reticuline + NADP(+) = 1,2-dehydroreticuline + H(+) + NADPH.	got7fsn_ti	(R)-reticuline:NADP+ oxidoreductase activity|1,2-dehydroreticulinium ion reductase activity											MetaCyc:1.5.1.27-RXN|KEGG_REACTION:R04695|EC:1.5.1.27|RHEA:17569		molecular_function											owl:Class	
GO:0034578	biolink:NamedThing	limonene 8-hydratase activity	Catalysis of the reaction: limonene + H2O = alpha-terpineol.	got7fsn_ti												UM-BBD_reactionID:r0916		molecular_function											owl:Class	
GO:0097683	biolink:NamedThing	dinoflagellate apex	The anterior most point of a dinoflagellate epicone.	got7fsn_ti	apex				The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-12-18T09:29:51Z						cellular_component											owl:Class	
GO:1990025	biolink:NamedThing	F bouton	Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles.	got7fsn_ti							pr	2013-02-06T10:29:42Z				NIF_Subcellular:nlx_subcell_100206		cellular_component											owl:Class	
GO:0032301	biolink:NamedThing	MutSalpha complex	A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.	got7fsn_ti	MMR complex|MSH2/MSH6 complex													cellular_component											owl:Class	
GO:0007524	biolink:NamedThing	adult visceral muscle development	The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0010201	biolink:NamedThing	response to continuous far red light stimulus by the high-irradiance response system	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence.	got7fsn_ti														biological_process											owl:Class	
GO:0007543	biolink:NamedThing	sex determination, somatic-gonadal interaction	The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism.	got7fsn_ti	sex determination, somatic/gonadal interaction													biological_process											owl:Class	
GO:0050355	biolink:NamedThing	triphosphatase activity	Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.	got7fsn_ti	triphosphate phosphohydrolase activity|tripolyphosphatase activity|inorganic triphosphatase activity											RHEA:14157|MetaCyc:TRIPHOSPHATASE-RXN|KEGG_REACTION:R00138|EC:3.6.1.25		molecular_function											owl:Class	
GO:0043880	biolink:NamedThing	crotonyl-CoA reductase activity	Catalysis of the reduction of crotonyl-CoA to butyryl-CoA.	got7fsn_ti	crotonyl-coenzyme A reductase activity|CCR													molecular_function											owl:Class	
GO:0044382	biolink:NamedThing	CLRC complex localization to heterochromatin	The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation.	got7fsn_ti	CLRC ubiquitin ligase complex localization to heterochromatin|CLRC ubiquitin ligase complex localisation to heterochromatin						jl	2011-12-13T03:37:18Z						biological_process											owl:Class	
GO:0097355	biolink:NamedThing	protein localization to heterochromatin	Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin.	got7fsn_ti	protein localisation to heterochromatin						pr	2012-07-03T03:19:07Z						biological_process											owl:Class	
GO:0043806	biolink:NamedThing	keto acid formate lyase activity	Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate.	got7fsn_ti	keto-acid formate acetyltransferase|keto-acid formate-lyase activity|keto-acid formate lyase activity											MetaCyc:KETOBUTFORMLY-RXN|EC:2.3.1.-		molecular_function											owl:Class	
GO:0097302	biolink:NamedThing	lipoprotein biosynthetic process via diacylglyceryl transfer	The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex.	got7fsn_ti	lipoprotein biosynthesis (diacylglyceryl transfer)						pr	2012-05-15T01:02:02Z						biological_process											owl:Class	
GO:0042158	biolink:NamedThing	lipoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.	got7fsn_ti	lipoprotein formation|lipoprotein synthesis|lipoprotein anabolism|lipoprotein biosynthesis													biological_process											owl:Class	
GO:0050643	biolink:NamedThing	10-deacetylbaccatin III 10-O-acetyltransferase activity	Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA.	got7fsn_ti	acetyl-CoA:taxan-10beta-ol O-acetyltransferase											EC:2.3.1.167|RHEA:20137|KEGG_REACTION:R06311|MetaCyc:2.3.1.167-RXN		molecular_function											owl:Class	
GO:0044341	biolink:NamedThing	sodium-dependent phosphate transport	The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions.	got7fsn_ti							jl	2010-08-20T04:16:15Z						biological_process											owl:Class	
GO:0006817	biolink:NamedThing	phosphate ion transport	The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	phosphate transport													biological_process											owl:Class	
GO:1904516	biolink:NamedThing	myofibroblast cell apoptotic process	Any apoptotic process in a myofibroblast cell.	got7fsn_ti	myofibroblast cell apoptosis|MFB apoptotic process|MFB apoptosis						sl	2015-07-28T18:29:08Z						biological_process											owl:Class	
GO:0120169	biolink:NamedThing	detection of cold stimulus involved in thermoception	The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception.	got7fsn_ti	sensory transduction of cold stimulus during thermoception|sensory detection of cold stimulus during thermoception|thermoception, sensory detection of cold stimulus|thermoception, sensory transduction of cold stimulus						krc	2018-05-21T20:36:05Z						biological_process											owl:Class	
GO:0050960	biolink:NamedThing	detection of temperature stimulus involved in thermoception	The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.	got7fsn_ti	sensory detection of temperature stimulus during thermoception|sensory detection of thermal stimulus during thermoception|sensory transduction of temperature stimulus during thermoception|thermoception, sensory transduction of temperature stimulus|sensory transduction of thermal stimulus during thermoception|thermoception, sensory transduction of thermal stimulus|thermoception, sensory detection of temperature stimulus|thermoception, sensory detection of thermal stimulus													biological_process											owl:Class	
GO:0033620	biolink:NamedThing	Mei2 nuclear dot complex	A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I.	got7fsn_ti	Mei2 nuclear dot|Mei2 dot|nuclear body													cellular_component											owl:Class	
GO:0102471	biolink:NamedThing	2-hydroxynaringenin-6C-glucoside dehydratase activity	Catalysis of the reaction: 6C-glucosyl-2-hydroxynaringenin <=> isovitexin-7-olate + H2O.	got7fsn_ti												MetaCyc:RXN-14076		molecular_function											owl:Class	
GO:0003094	biolink:NamedThing	glomerular filtration	The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.	got7fsn_ti														biological_process											owl:Class	
GO:0097205	biolink:NamedThing	renal filtration	A renal system process in which fluid circulating through the body is filtered through a barrier system.	got7fsn_ti							pr	2012-01-03T03:10:17Z						biological_process											owl:Class	
GO:0033935	biolink:NamedThing	oligoxyloglucan beta-glycosidase activity	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.	got7fsn_ti	oligoxyloglucan xyloglucohydrolase activity|oligoxyloglucan hydrolase activity|isoprimeverose-producing oligoxyloglucan hydrolase activity											MetaCyc:3.2.1.120-RXN|EC:3.2.1.120		molecular_function											owl:Class	
GO:0033948	biolink:NamedThing	fructan beta-(2,1)-fructosidase activity	Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.	got7fsn_ti	beta-(2,1)-D-fructan fructohydrolase activity|beta-(2,1)-fructan exohydrolase activity|1-FEH II|1-fructan exohydrolase activity|beta-(2,1)-linkage-specific fructan-beta-fructosidase activity|1-FEH w1|1-FEH w2											MetaCyc:3.2.1.153-RXN|EC:3.2.1.153		molecular_function											owl:Class	
GO:0102029	biolink:NamedThing	D-lactate dehydrogenase (quinone) activity	Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol.	got7fsn_ti												RHEA:51468|MetaCyc:DLACTDEHYDROGFAD-RXN|EC:1.1.5.12		molecular_function											owl:Class	
GO:0010972	biolink:NamedThing	negative regulation of G2/M transition of mitotic cell cycle	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.	got7fsn_ti	negative regulation of mitotic entry						tb	2009-06-01T10:18:29Z						biological_process											owl:Class	
GO:0102673	biolink:NamedThing	fatty aldehyde dehydrogenase activity	Catalysis of the reaction: NAD(1-) + H2O + a fatty aldehyde <=> NADH(2-) + 2 H+ + a fatty acid.	got7fsn_ti												MetaCyc:RXN-4142		molecular_function											owl:Class	
GO:0018774	biolink:NamedThing	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity	Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate.	got7fsn_ti	2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase activity|HOHPDA hydrolase activity|2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase activity											EC:3.7.1.8|MetaCyc:3.7.1.8-RXN|UM-BBD_enzymeID:e0033|RHEA:17161		molecular_function											owl:Class	
GO:0061599	biolink:NamedThing	molybdopterin molybdotransferase activity	Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.	got7fsn_ti							dph	2014-02-10T14:30:31Z				EC:2.10.1.1|Reactome:R-HSA-947531|RHEA:35047		molecular_function											owl:Class	
GO:0036292	biolink:NamedThing	DNA rewinding	The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA.	got7fsn_ti	single-stranded DNA bubble rewinding|DNA annealing|RPA-dependent DNA rewinding						bf	2012-07-18T10:43:41Z						biological_process											owl:Class	
GO:0055094	biolink:NamedThing	response to lipoprotein particle	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.	got7fsn_ti	response to lipoprotein particle stimulus													biological_process											owl:Class	
GO:0048496	biolink:NamedThing	maintenance of animal organ identity	The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0015516	biolink:NamedThing	tartrate:succinate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out).	got7fsn_ti														molecular_function											owl:Class	
GO:0015554	biolink:NamedThing	tartrate transmembrane transporter activity	Enables the transfer of tartrate from one side of a membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria.	got7fsn_ti														molecular_function											owl:Class	
GO:0033985	biolink:NamedThing	acidocalcisome lumen	The volume enclosed by the membranes of an acidocalcisome.	got7fsn_ti														cellular_component											owl:Class	
GO:0019155	biolink:NamedThing	3-(imidazol-5-yl)lactate dehydrogenase activity	Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+.	got7fsn_ti	imidazol-5-yl lactate dehydrogenase activity|(S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase activity											MetaCyc:IMILACTDEHYDROG-RXN|EC:1.1.1.111		molecular_function											owl:Class	
GO:0047751	biolink:NamedThing	cholestenone 5-alpha-reductase activity	Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH.	got7fsn_ti	3-oxosteroid delta4-dehydrogenase|testosterone 5alpha-reductase|3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity|steroid 5alpha-reductase|testosterone delta4-hydrogenase activity|delta4-3-ketosteroid 5alpha-oxidoreductase activity|cholestenone 5alpha-reductase activity|3-oxosteroid 5alpha-reductase activity|4-ene-3-oxosteroid 5alpha-reductase activity|5alpha-reductase|testosterone delta4-5alpha-reductase activity|reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase activity|steroid 5alpha-hydrogenase activity|4-ene-5alpha-reductase activity|cholestenone 5a-reductase activity|cholest-4-en-3-one 5alpha-reductase activity											MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN|KEGG_REACTION:R02610|EC:1.3.1.22|RHEA:24552		molecular_function											owl:Class	
GO:0035456	biolink:NamedThing	response to interferon-beta	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.	got7fsn_ti	response to fibroblast interferon|response to fiblaferon|response to interferon beta|response to beta-1 interferon						bf	2010-04-16T11:06:12Z						biological_process											owl:Class	
GO:0019536	biolink:NamedThing	vibriobactin metabolic process	The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae.	got7fsn_ti	vibriobactin metabolism													biological_process											owl:Class	
GO:0009524	biolink:NamedThing	phragmoplast	Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules.	got7fsn_ti												Wikipedia:Phragmoplast		cellular_component											owl:Class	
GO:0098030	biolink:NamedThing	icosahedral viral capsid, neck	A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae).	got7fsn_ti							bm	2012-07-19T14:56:28Z						cellular_component											owl:Class	
GO:0097677	biolink:NamedThing	STAT family protein binding	Binding to a member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.	got7fsn_ti	signal transducers and activators of transcription family protein binding						pr	2014-11-04T11:31:03Z						molecular_function											owl:Class	
GO:0032115	biolink:NamedThing	sorbose reductase activity	Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction.	got7fsn_ti	D-glucitol:NADP+ oxidoreductase activity|Sou1p											KEGG_REACTION:R07346|RHEA:14609|MetaCyc:1.1.1.289-RXN|EC:1.1.1.289		molecular_function											owl:Class	
GO:0070523	biolink:NamedThing	11-beta-hydroxysteroid dehydrogenase (NAD+) activity	Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21915										Wikipedia:11beta-hydroxysteroid_dehydrogenase|RHEA:53116		molecular_function											owl:Class	
GO:0044873	biolink:NamedThing	lipoprotein localization to membrane	A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.	got7fsn_ti							jl	2014-11-25T16:28:43Z						biological_process											owl:Class	
GO:0044872	biolink:NamedThing	lipoprotein localization	Any process in which a lipoprotein is transported to, or maintained in, a specific location.	got7fsn_ti							jl	2014-11-25T16:27:06Z						biological_process											owl:Class	
GO:0018457	biolink:NamedThing	perillyl-alcohol dehydrogenase activity	Catalysis of the reaction: NAD(+) + perillyl alcohol = H(+) + NADH + perillyl aldehyde.	got7fsn_ti	perillyl alcohol dehydrogenase activity|perillyl-alcohol:NAD+ oxidoreductase activity											EC:1.1.1.144|UM-BBD_reactionID:r0729|RHEA:10664|MetaCyc:PERILLYL-ALCOHOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03945		molecular_function											owl:Class	
GO:0018777	biolink:NamedThing	1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity	Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol).	got7fsn_ti														molecular_function											owl:Class	
GO:1990525	biolink:NamedThing	BIR domain binding	Binding to a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain.	got7fsn_ti	Baculovirus Inhibitor of apoptosis protein Repeat domain binding				An example of this is the Drosophila reaper gene in PMID:21886178.		jl	2014-11-04T12:36:56Z						molecular_function											owl:Class	
GO:0062148	biolink:NamedThing	L-gamma-glutamyl-L-propargylglycine hydroxylase activity	Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate.	got7fsn_ti							dph	2019-09-02T17:04:43Z				RHEA:59900		molecular_function											owl:Class	
GO:0048356	biolink:NamedThing	root epithelial mucilage biosynthetic process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.	got7fsn_ti	root epithelial mucilage formation|root epithelial mucilage biosynthesis|root epithelial mucilage synthesis|root epithelial mucilage anabolism													biological_process											owl:Class	
GO:0000326	biolink:NamedThing	protein storage vacuole	A storage vacuole that contains a lytic vacuole; identified in plants.	got7fsn_ti														cellular_component											owl:Class	
GO:0061781	biolink:NamedThing	mitotic cohesin unloading	Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle.	got7fsn_ti							dph	2016-08-24T09:43:07Z						biological_process											owl:Class	
GO:0042554	biolink:NamedThing	superoxide anion generation	The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.	got7fsn_ti	superoxide release													biological_process											owl:Class	
GO:0006801	biolink:NamedThing	superoxide metabolic process	The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.	got7fsn_ti	superoxide free radical metabolic process|oxygen free radical metabolic process|superoxide free radical metabolism|oxygen free radical metabolism|superoxide metabolism													biological_process											owl:Class	
GO:0102033	biolink:NamedThing	long-chain fatty acid omega-hydroxylase activity	Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti	cytochrome P450 fatty acid omega-hydroxylase activity	https://github.com/geneontology/go-ontology/issues/14194|https://github.com/geneontology/go-ontology/issues/19899										EC:1.14.14.80|RHEA:56748|MetaCyc:RXN-16394		molecular_function											owl:Class	
GO:0120250	biolink:NamedThing	fatty acid omega-hydroxylase activity	Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19899					krc	2020-09-01T00:19:13Z				RHEA:39023		molecular_function											owl:Class	
GO:0035925	biolink:NamedThing	mRNA 3'-UTR AU-rich region binding	Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs.	got7fsn_ti	mRNA 3'-UTR adenylate/uridylate-rich element binding|AU-rich element binding|adenylate/uridylate-rich element binding|ARE binding	https://github.com/geneontology/go-ontology/issues/16842					bf	2011-07-19T09:30:18Z			GO:0017091			molecular_function											owl:Class	
GO:0102154	biolink:NamedThing	8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity	Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 8C-glucosyl-2-hydroxynaringenin + UDP + 2 H+.	got7fsn_ti												MetaCyc:RXN-11685		molecular_function											owl:Class	
GO:0043061	biolink:NamedThing	meiotic metaphase II plate congression	The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II.	got7fsn_ti														biological_process											owl:Class	
GO:0075271	biolink:NamedThing	zygosporangium development	The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes.	got7fsn_ti														biological_process											owl:Class	
GO:0061254	biolink:NamedThing	mesonephric glomerular parietal epithelial cell development	The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	got7fsn_ti							dph	2010-08-30T01:30:36Z						biological_process											owl:Class	
GO:0072016	biolink:NamedThing	glomerular parietal epithelial cell development	The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	got7fsn_ti	Bowman's capsule development						mah	2010-01-25T02:13:16Z						biological_process											owl:Class	
GO:0035478	biolink:NamedThing	chylomicron binding	Binding to a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.	got7fsn_ti							bf	2010-04-23T10:18:52Z						molecular_function											owl:Class	
GO:0061038	biolink:NamedThing	uterus morphogenesis	The process in which anatomical structures of the uterus are generated and organized.	got7fsn_ti							dph	2010-02-22T11:12:35Z						biological_process											owl:Class	
GO:0038104	biolink:NamedThing	nodal receptor complex	A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell.	got7fsn_ti	ActRIIB.ALK4.EGF-CFC complex				Nodal signals through activin receptors but (unlike activin) also requires EGF-CFC coreceptors (such as Cripto or Cryptic in mammals) to signal. This term is intended for receptor/co-receptor components and not a nodal-receptor complex.		bf	2012-02-17T11:12:21Z						cellular_component											owl:Class	
GO:0045282	biolink:NamedThing	plasma membrane succinate dehydrogenase complex	A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Examples of this component are found in Bacterial species.	got7fsn_ti	succinate dehydrogenase complex													cellular_component											owl:Class	
GO:0062031	biolink:NamedThing	filamentous growth MAPK cascade	The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth.	got7fsn_ti							dph	2018-04-17T15:18:44Z						biological_process											owl:Class	
GO:0046895	biolink:NamedThing	N-terminal peptidyl-isoleucine methylation	The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine.	got7fsn_ti												RESID:AA0336		biological_process											owl:Class	
GO:0031412	biolink:NamedThing	gas vesicle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps.	got7fsn_ti	gas vesicle organization and biogenesis|gas vesicle formation|gas vesicle biosynthesis|gas vesicle organisation				Note that although gas vesicles are commonly referred to as 'vesicles' or 'vacuoles' in the literature, they are not surrounded by a membrane.									biological_process											owl:Class	
GO:0008753	biolink:NamedThing	NADPH dehydrogenase (quinone) activity	Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol.	got7fsn_ti	reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase|NADPH oxidase|NADPH:(quinone-acceptor) oxidoreductase											EC:1.6.5.10|KEGG_REACTION:R07359|MetaCyc:NADPH-DEHYDROGENASE-QUINONE-RXN|RHEA:46164		molecular_function											owl:Class	
GO:0003955	biolink:NamedThing	NAD(P)H dehydrogenase (quinone) activity	Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.	got7fsn_ti	vitamin-K reductase activity|diaphorase activity|p-benzoquinone reductase activity|reduced NAD(P)H dehydrogenase activity|NAD(P)H:(quinone-acceptor)oxidoreductase activity|Naphthoquinone reductase activity|NAD(P)H(2) dehydrogenase (quinone) activity|azoreductase activity|QR1|naphthoquinone reductase activity|NAD(P)H menadione reductase activity|quinone reductase activity|NQO1|NAD(P)H2 dehydrogenase (quinone)|flavoprotein NAD(P)H-quinone reductase activity|dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) activity|NAD(P)H-quinone oxidoreductase activity|reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase activity|viologen accepting pyridine nucleotide oxidoreductase activity|menadione reductase activity|NAD(P)H: menadione oxidoreductase activity|NAD(P)H-quinone dehydrogenase activity|phylloquinone reductase activity|NADH-menadione reductase activity|DT-diaphorase activity|menadione oxidoreductase activity|NAD(P)H:quinone oxidoreductase activity|NAD(P)H dehydrogenase activity|vitamin K reductase activity											EC:1.6.5.2|MetaCyc:NQOR-RXN|UM-BBD_reactionID:r0227		molecular_function											owl:Class	
GO:0018139	biolink:NamedThing	peptide cross-linking via L-phenylalanine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	got7fsn_ti												RESID:AA0243		biological_process											owl:Class	
GO:0035328	biolink:NamedThing	transcriptionally silent chromatin	The ordered and organized complex of DNA and protein that forms regions of the chromosome that are not being actively transcribed.	got7fsn_ti	transcriptionally inactive chromatin						bf	2010-02-26T10:24:13Z						cellular_component											owl:Class	
GO:0035868	biolink:NamedThing	alphav-beta3 integrin-HMGB1 complex	A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein.	got7fsn_ti	alphav-beta3 integrin-high mobility group box 1 complex|alphaV-beta3 integrin-HMGB1 complex						bf	2011-05-25T03:07:24Z						cellular_component											owl:Class	
GO:1990810	biolink:NamedThing	microtubule anchoring at mitotic spindle pole body	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.	got7fsn_ti							vw	2015-07-24T12:52:25Z						biological_process											owl:Class	
GO:0071622	biolink:NamedThing	regulation of granulocyte chemotaxis	Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.	got7fsn_ti							mah	2010-02-09T04:09:24Z						biological_process											owl:Class	
GO:0018097	biolink:NamedThing	protein-chromophore linkage via peptidyl-S-4-hydroxycinnamyl-L-cysteine	The synthesis of the chromophore S-4-hydroxycinnamyl-L-cysteine.	got7fsn_ti	protein amino acid cinnamylation											RESID:AA0207		biological_process											owl:Class	
GO:0106004	biolink:NamedThing	tRNA (guanine-N7)-methylation	The process whereby a guanine in a tRNA is methylated at the N7 position of guanine.	got7fsn_ti							hjd	2017-04-07T18:17:38Z						biological_process											owl:Class	
GO:0050513	biolink:NamedThing	glycoprotein 2-beta-D-xylosyltransferase activity	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H(+) + UDP.	got7fsn_ti	glycoprotein 2-b-D-xylosyltransferase activity|beta-1,2-xylosyltransferase activity|1,2-beta-xylosyltransferase activity											EC:2.4.2.38|KEGG_REACTION:R06016|MetaCyc:2.4.2.38-RXN|RHEA:10612		molecular_function											owl:Class	
GO:0047285	biolink:NamedThing	flavonol-3-O-glycoside xylosyltransferase activity	Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP.	got7fsn_ti	UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase activity											EC:2.4.2.35|RHEA:19701|MetaCyc:2.4.2.35-RXN		molecular_function											owl:Class	
GO:0008714	biolink:NamedThing	AMP nucleosidase activity	Catalysis of the reaction: AMP + H(2)O = D-ribose 5-phosphate + adenine.	got7fsn_ti	AMP phosphoribohydrolase activity|adenylate nucleosidase activity|adenosine monophosphate nucleosidase activity											EC:3.2.2.4|RHEA:20129|MetaCyc:AMP-NUCLEOSID-RXN|KEGG_REACTION:R00182		molecular_function											owl:Class	
GO:0035321	biolink:NamedThing	maintenance of imaginal disc-derived wing hair orientation	Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.	got7fsn_ti	maintenance of wing hair orientation													biological_process											owl:Class	
GO:0021541	biolink:NamedThing	ammon gyrus development	The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.	got7fsn_ti	cornu ammonis development|Ammon's horn development													biological_process											owl:Class	
GO:0008414	biolink:NamedThing	CDP-alcohol phosphotransferase activity	Catalysis of the transfer of a CDP-alcohol group from one compound to another.	got7fsn_ti														molecular_function											owl:Class	
GO:0070027	biolink:NamedThing	carbon monoxide sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).	got7fsn_ti														molecular_function											owl:Class	
GO:0070025	biolink:NamedThing	carbon monoxide binding	Binding to carbon monoxide (CO).	got7fsn_ti	CO binding													molecular_function											owl:Class	
GO:0101026	biolink:NamedThing	mitotic nuclear membrane biogenesis	A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division.	got7fsn_ti	nuclear membrane biogenesis involved in mitotic nuclear division													biological_process											owl:Class	
GO:0101025	biolink:NamedThing	nuclear membrane biogenesis	The process in which a nuclear membrane is synthesized, aggregates, and bonds together.	got7fsn_ti														biological_process											owl:Class	
GO:0048264	biolink:NamedThing	determination of ventral identity	The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti	determination of abaxial identity													biological_process											owl:Class	
GO:0045824	biolink:NamedThing	negative regulation of innate immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.	got7fsn_ti	downregulation of innate immune response|inhibition of innate immune response|down-regulation of innate immune response|down regulation of innate immune response													biological_process											owl:Class	
GO:1990760	biolink:NamedThing	osmolarity-sensing cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.	got7fsn_ti							sl	2015-06-05T21:58:50Z						molecular_function											owl:Class	
GO:1990973	biolink:NamedThing	transmembrane actin-associated (TAN) line	A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge).	got7fsn_ti	TAN line						hjd	2016-06-22T15:05:09Z						cellular_component											owl:Class	
GO:0001827	biolink:NamedThing	inner cell mass cell fate commitment	The cell fate commitment of precursor cells that will become inner cell mass cells.	got7fsn_ti					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, compacted morula ; EMAP:13' and 'TS4, inner cell mass ; EMAP:14'.									biological_process											owl:Class	
GO:0097204	biolink:NamedThing	phagocytic cup base	The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking.	got7fsn_ti							pr	2011-12-21T10:29:07Z						cellular_component											owl:Class	
GO:0046892	biolink:NamedThing	peptidyl-S-carbamoyl-L-cysteine dehydration	The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.	got7fsn_ti	formation of peptidyl-S-cyanocysteine|formation of peptidyl-serine thiocyanate ester											RESID:AA0333		biological_process											owl:Class	
GO:0019841	biolink:NamedThing	retinol binding	Binding to retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.	got7fsn_ti	vitamin A1 alcohol binding|vitamin A1 binding													molecular_function											owl:Class	
GO:0004895	biolink:NamedThing	cell adhesion receptor activity	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell and to initiate intracellular signaling. Cell adhesion receptors include integrins and cadherins.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15237			Reinstated term from obsolete.									molecular_function											owl:Class	
GO:0050499	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H.	got7fsn_ti												EC:1.20.1.-		molecular_function											owl:Class	
GO:0009094	biolink:NamedThing	L-phenylalanine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.	got7fsn_ti	phenylalanine biosynthetic process, prephenate pathway|L-phenylalanine biosynthesis|L-phenylalanine anabolism|phenylalanine biosynthesis|phenylalanine biosynthetic process|phenylalanine biosynthetic process, shikimate pathway|L-phenylalanine formation|L-phenylalanine synthesis										GO:0019274|GO:0019275			biological_process											owl:Class	
GO:0106154	biolink:NamedThing	perithecium formation	The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.	got7fsn_ti							hjd	2018-09-19T19:12:53Z						biological_process											owl:Class	
GO:0035698	biolink:NamedThing	CD8-positive, alpha-beta cytotoxic T cell extravasation	The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue.	got7fsn_ti							bf	2011-02-28T03:09:53Z						biological_process											owl:Class	
GO:0036168	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to heat	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature.	got7fsn_ti							bf	2012-03-27T03:53:28Z						biological_process											owl:Class	
GO:0110013	biolink:NamedThing	positive regulation of aggregation involved in sorocarp development	Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.	got7fsn_ti							kmv	2017-05-10T12:52:46Z						biological_process											owl:Class	
GO:0097025	biolink:NamedThing	MPP7-DLG1-LIN7 complex	A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions.	got7fsn_ti							pr	2011-03-30T05:03:33Z						cellular_component											owl:Class	
GO:0033186	biolink:NamedThing	CAF-1 complex	A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.	got7fsn_ti	chromatin assembly factor 1 complex				In yeast the subunits are MSI1/p50, CAC2/p60 and CAC1/p90.									cellular_component											owl:Class	
GO:0007303	biolink:NamedThing	cytoplasmic transport, nurse cell to oocyte	The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte.	got7fsn_ti														biological_process											owl:Class	
GO:0019430	biolink:NamedThing	removal of superoxide radicals	Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).	got7fsn_ti	removal of oxygen free radicals|removal of O2-|cellular detoxification of superoxide radicals											MetaCyc:DETOX1-PWY		biological_process											owl:Class	
GO:0061161	biolink:NamedThing	positive regulation of establishment of bipolar cell polarity regulating cell shape	Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.	got7fsn_ti							dph	2010-06-23T09:26:45Z						biological_process											owl:Class	
GO:0061173	biolink:NamedThing	positive regulation of establishment of bipolar cell polarity	Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity.	got7fsn_ti							dph	2010-06-30T08:59:20Z						biological_process											owl:Class	
GO:0044350	biolink:NamedThing	micropinocytosis	An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm.	got7fsn_ti	single-organism micropinocytosis|clathrin-independent pinocytosis						jl	2013-12-02T14:26:30Z			GO:1902540			biological_process											owl:Class	
GO:0006907	biolink:NamedThing	pinocytosis	An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.	got7fsn_ti	fluid-phase endocytosis|clathrin-independent pinocytosis|single-organism pinocytosis						jl	2013-12-02T14:14:38Z			GO:0006908|GO:1902536	Wikipedia:Pinocytosis		biological_process											owl:Class	
GO:0047722	biolink:NamedThing	indolelactate dehydrogenase (NADH) activity	Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD(+) = 3-(indol-3-yl)pyruvate + H(+) + NADH.	got7fsn_ti	indole-3-lactate dehydrogenase activity|(indol-3-yl)lactate:NAD+ oxidoreductase activity|indolelactate:NAD+ oxidoreductase activity											KEGG_REACTION:R01971|EC:1.1.1.110|MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN|RHEA:20133		molecular_function											owl:Class	
GO:0034237	biolink:NamedThing	protein kinase A regulatory subunit binding	Binding to one or both of the regulatory subunits of protein kinase A.	got7fsn_ti	protein kinase A anchoring activity|PKA regulatory subunit binding													molecular_function											owl:Class	
GO:0031842	biolink:NamedThing	type 1 neuropeptide Y receptor binding	Binding to a type 1 neuropeptide Y receptor.	got7fsn_ti	type 1 neuropeptide Y receptor ligand													molecular_function											owl:Class	
GO:0051658	biolink:NamedThing	maintenance of nucleus location	Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of cell nucleus location|maintenance of nucleus localization													biological_process											owl:Class	
GO:0010854	biolink:NamedThing	adenylate cyclase regulator activity	Binds to and modulates the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0035213	biolink:NamedThing	clypeo-labral disc development	The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite.	got7fsn_ti	development of structures derived from the clypeo-labral disc													biological_process											owl:Class	
GO:0046947	biolink:NamedThing	hydroxylysine biosynthetic process	The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.	got7fsn_ti	hydroxylysine anabolism|hydroxylysine biosynthesis|hydroxylysine formation|hydroxylysine synthesis													biological_process											owl:Class	
GO:0102453	biolink:NamedThing	anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity	Catalysis of the reaction: 4-coumaryl-CoA + H+ + an anthocyanidin-3-O-beta-D-glucoside = coenzyme A + H+ + an anthocyanidin-3-O-[6-O-(hydroxycinnamoyl)-beta-D-glucoside].	got7fsn_ti												RHEA:35411|MetaCyc:RXN-13959|EC:2.3.1.215		molecular_function											owl:Class	
GO:0009206	biolink:NamedThing	purine ribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine ribonucleoside triphosphate biosynthesis|purine ribonucleoside triphosphate synthesis|purine ribonucleoside triphosphate formation|purine ribonucleoside triphosphate anabolism													biological_process											owl:Class	
GO:0040032	biolink:NamedThing	post-embryonic body morphogenesis	The process in which the anatomical structures of the post-embryonic soma are generated and organized.	got7fsn_ti					Note that this term was 'body morphogenesis (sensu Nematoda)'.									biological_process											owl:Class	
GO:0033845	biolink:NamedThing	hydroxymethylfurfural reductase (NADPH) activity	Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.	got7fsn_ti														molecular_function											owl:Class	
GO:0002196	biolink:NamedThing	Ser-tRNA(Ala) hydrolase activity	Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).	got7fsn_ti							hjd	2011-09-30T02:18:50Z						molecular_function											owl:Class	
GO:0044750	biolink:NamedThing	high-affinity nickel cation transmembrane transporter activity	Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti							jl	2012-11-20T15:15:59Z						molecular_function											owl:Class	
GO:0015099	biolink:NamedThing	nickel cation transmembrane transporter activity	Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.	got7fsn_ti	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity											RHEA:29831		molecular_function											owl:Class	
GO:0045089	biolink:NamedThing	positive regulation of innate immune response	Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.	got7fsn_ti	stimulation of innate immune response|up-regulation of innate immune response|up regulation of innate immune response|upregulation of innate immune response													biological_process											owl:Class	
GO:0106034	biolink:NamedThing	protein maturation by [2Fe-2S] cluster transfer	The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.	got7fsn_ti							hjd	2017-07-07T17:24:59Z						biological_process											owl:Class	
GO:0071799	biolink:NamedThing	cellular response to prostaglandin D stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.	got7fsn_ti							mah	2010-09-03T10:48:35Z						biological_process											owl:Class	
GO:0015052	biolink:NamedThing	beta3-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors.	got7fsn_ti	beta3 adrenoceptor													molecular_function											owl:Class	
GO:0004939	biolink:NamedThing	beta-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.	got7fsn_ti	beta adrenoceptor													molecular_function											owl:Class	
GO:0006847	biolink:NamedThing	plasma membrane acetate transport	The directed movement of acetate across a plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0035433	biolink:NamedThing	acetate transmembrane transport	The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.	got7fsn_ti	acetate membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T10:59:01Z						biological_process											owl:Class	
GO:0009150	biolink:NamedThing	purine ribonucleotide metabolic process	The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine ribonucleotide metabolism													biological_process											owl:Class	
GO:0047850	biolink:NamedThing	diaminopimelate dehydrogenase activity	Catalysis of the reaction: meso-2,6-diaminopimelate + H(2)O + NADP(+) = L-2-amino-6-oxopimelate + H(+) + NADPH + NH(4)(+).	got7fsn_ti	meso-alpha,epsilon-diaminopimelate dehydrogenase activity|meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)|meso-diaminopimelate dehydrogenase activity|meso-diaminopimelate D-dehydrogenase activity											EC:1.4.1.16|RHEA:13561|MetaCyc:DIAMINOPIMELATE-DEHYDROGENASE-RXN|KEGG_REACTION:R02755		molecular_function											owl:Class	
GO:0045197	biolink:NamedThing	establishment or maintenance of epithelial cell apical/basal polarity	Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.	got7fsn_ti														biological_process											owl:Class	
GO:0098838	biolink:NamedThing	folate transmembrane transport	The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane.	got7fsn_ti	folic acid transmembrane transport|reduced folate transmembrane transport	https://github.com/geneontology/go-ontology/issues/15461												biological_process											owl:Class	
GO:0035461	biolink:NamedThing	vitamin transmembrane transport	The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	got7fsn_ti	vitamin membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-19T10:21:41Z						biological_process											owl:Class	
GO:0086028	biolink:NamedThing	bundle of His cell to Purkinje myocyte signaling	Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.	got7fsn_ti	bundle of His cardiac muscle cell to Purkinje myocyte signaling|bundle of His cardiac muscle cell to Purkinje myocyte signalling						tb	2011-11-11T02:02:14Z						biological_process											owl:Class	
GO:0061770	biolink:NamedThing	translation elongation factor binding	Binding to a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.	got7fsn_ti							dph	2016-07-09T09:31:11Z						molecular_function											owl:Class	
GO:0033204	biolink:NamedThing	ribonuclease P RNA binding	Binding to RNA subunit of ribonuclease P.	got7fsn_ti	RNase P RNA binding													molecular_function											owl:Class	
GO:0001860	biolink:NamedThing	complement component C3d receptor activity	Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0046356	biolink:NamedThing	acetyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.	got7fsn_ti	acetyl-CoA catabolism|acetyl-CoA breakdown|acetyl-CoA degradation													biological_process											owl:Class	
GO:0099081	biolink:NamedThing	supramolecular polymer	A polymeric supramolecular structure.	got7fsn_ti														cellular_component											owl:Class	
GO:0021653	biolink:NamedThing	rhombomere 1 structural organization	The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti	rhombomere 1 structural organisation													biological_process											owl:Class	
GO:0030284	biolink:NamedThing	estrogen receptor activity	Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.	got7fsn_ti					For estrogen receptors that function within the nucleus to modulate transcription, consider instead annotating to the child terms 'estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ; GO:0038052' or 'estrogen-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038053'.									molecular_function											owl:Class	
GO:0030858	biolink:NamedThing	positive regulation of epithelial cell differentiation	Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation.	got7fsn_ti	stimulation of epithelial cell differentiation|activation of epithelial cell differentiation|up-regulation of epithelial cell differentiation|upregulation of epithelial cell differentiation|up regulation of epithelial cell differentiation													biological_process											owl:Class	
GO:0047829	biolink:NamedThing	D-nopaline dehydrogenase activity	Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH.	got7fsn_ti	nopaline synthase activity|NOS activity|N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)|D-nopaline synthase activity|2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)|nopaline dehydrogenase activity											EC:1.5.1.19|RHEA:19637|MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0070287	biolink:NamedThing	ferritin receptor activity	Combining with ferritin, and delivering ferritin into the cell via endocytosis.	got7fsn_ti	ferritin complex receptor activity													molecular_function											owl:Class	
GO:1990917	biolink:NamedThing	ooplasm	The cytoplasm of an ovum.	got7fsn_ti							sl	2015-12-10T21:40:16Z						cellular_component											owl:Class	
GO:0097656	biolink:NamedThing	cell-cell self recognition	A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development.	got7fsn_ti	self recognition|kin discrimination|kin recognition				Examples are the membrane proteins TgrB1 and TgrC1 in the social amoeba Dictyostelium discoideum.		pr	2014-09-24T20:58:35Z						biological_process											owl:Class	
GO:0061613	biolink:NamedThing	glycolytic process from glycerol	The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH.	got7fsn_ti							dph	2014-04-04T08:26:57Z						biological_process											owl:Class	
GO:0047217	biolink:NamedThing	sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity	Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose.	got7fsn_ti	water-soluble-glucan synthase activity|GTF-S|sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase activity|sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase|sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase activity											MetaCyc:2.4.1.125-RXN|EC:2.4.1.125		molecular_function											owl:Class	
GO:0045505	biolink:NamedThing	dynein intermediate chain binding	Binding to an intermediate chain of the dynein complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0051756	biolink:NamedThing	meiotic sister chromatid centromere separation	The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0051552	biolink:NamedThing	flavone metabolic process	The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).	got7fsn_ti	2-phenylchromone metabolic process|flavone metabolism|2-phenyl-4H-1-benzopyran-4-one metabolic process|2-phenyl-4H-1-benzopyran-4-one metabolism|2-phenylchromone metabolism													biological_process											owl:Class	
GO:0102233	biolink:NamedThing	crotonaldehyde redutase activity	Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP.	got7fsn_ti												MetaCyc:RXN-12292		molecular_function											owl:Class	
GO:0010917	biolink:NamedThing	negative regulation of mitochondrial membrane potential	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	got7fsn_ti	reduction of mitochondrial membrane potential													biological_process											owl:Class	
GO:0045837	biolink:NamedThing	negative regulation of membrane potential	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	got7fsn_ti	downregulation of membrane potential|down regulation of membrane potential|down-regulation of membrane potential|inhibition of membrane potential|reduction of membrane potential													biological_process											owl:Class	
GO:0061544	biolink:NamedThing	peptide secretion, neurotransmission	The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-25T09:10:10Z						biological_process											owl:Class	
GO:1990168	biolink:NamedThing	protein K33-linked deubiquitination	A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.	got7fsn_ti							sp	2013-08-14T11:19:39Z						biological_process											owl:Class	
GO:0061320	biolink:NamedThing	pericardial nephrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	got7fsn_ti	pericardial cell differentiation						dph	2010-09-24T12:25:53Z			GO:0007513			biological_process											owl:Class	
GO:0034785	biolink:NamedThing	salicylate 5-hydroxylase activity	Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+.	got7fsn_ti												UM-BBD_reactionID:r1034|RHEA:35307|EC:1.14.13.172|MetaCyc:RXN-10446		molecular_function											owl:Class	
GO:0061981	biolink:NamedThing	3-hydroxykynureninase activity	Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.	got7fsn_ti							dph	2018-02-14T16:12:49Z				RHEA:25143		molecular_function											owl:Class	
GO:0018465	biolink:NamedThing	vanillyl-alcohol oxidase activity	Catalysis of the reaction: O(2) + vanillyl alcohol = H(2)O(2) + vanillin.	got7fsn_ti	4-hydroxy-2-methoxybenzyl alcohol oxidase activity|vanillyl alcohol:oxygen oxidoreductase activity											RHEA:10036|KEGG_REACTION:R02877|MetaCyc:1.1.3.38-RXN|EC:1.1.3.38|UM-BBD_reactionID:r0651		molecular_function											owl:Class	
GO:0070776	biolink:NamedThing	MOZ/MORF histone acetyltransferase complex	A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.	got7fsn_ti							mah	2009-07-02T12:06:04Z						cellular_component											owl:Class	
GO:0050127	biolink:NamedThing	N-carbamoylsarcosine amidase activity	Catalysis of the reaction: N-carbamoylsarcosine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + sarcosine.	got7fsn_ti	CSHase activity|N-carbamoylsarcosine amidohydrolase activity|carbamoylsarcosine amidase activity											KEGG_REACTION:R01563|RHEA:20057|EC:3.5.1.59|MetaCyc:N-CARBAMOYLSARCOSINE-AMIDASE-RXN		molecular_function											owl:Class	
GO:0001896	biolink:NamedThing	autolysis	A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.	got7fsn_ti												Wikipedia:Autolysis		biological_process											owl:Class	
GO:0042423	biolink:NamedThing	catecholamine biosynthetic process	The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	got7fsn_ti	catecholamine biosynthesis|catecholamine formation|catecholamine anabolism|catecholamine synthesis											Wikipedia:Catecholamines		biological_process											owl:Class	
GO:0031870	biolink:NamedThing	thromboxane A2 receptor binding	Binding to a thromboxane A2 receptor.	got7fsn_ti	thromboxane A2 receptor ligand|prostanoid TP receptor binding													molecular_function											owl:Class	
GO:0044609	biolink:NamedThing	DBIRD complex	A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD.	got7fsn_ti							jl	2012-05-30T03:04:23Z						cellular_component											owl:Class	
GO:0070114	biolink:NamedThing	organellar chromatophore outer membrane	The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore.	got7fsn_ti	Paulinella-type chromatophore outer membrane													cellular_component											owl:Class	
GO:0061493	biolink:NamedThing	central plaque of mitotic spindle pole body	One of three laminate structures that form the mitotic spindle pole body; the inner plaque is on the nuclear face of the spindle pole body.	got7fsn_ti							dph	2012-12-11T09:08:26Z						cellular_component											owl:Class	
GO:0090543	biolink:NamedThing	Flemming body	A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.	got7fsn_ti	Midbody ring						tb	2013-02-14T17:24:43Z						cellular_component											owl:Class	
GO:0019087	biolink:NamedThing	transformation of host cell by virus	A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication.	got7fsn_ti	host cell transformation|immortalization of host cell|viral transformation of host cell|transformation of host cell|viral immortalization|host cell immortalization|viral transformation|immortalization of host cell by virus										GO:0020021|GO:0019088	Wikipedia:Viral_transformation		biological_process											owl:Class	
GO:0034527	biolink:NamedThing	1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene.	got7fsn_ti												UM-BBD_reactionID:r0790		molecular_function											owl:Class	
GO:0003104	biolink:NamedThing	positive regulation of glomerular filtration	Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.	got7fsn_ti														biological_process											owl:Class	
GO:0004380	biolink:NamedThing	glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.	got7fsn_ti	histo-blood group A glycosyltransferase (Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase)|A transferase activity|A-transferase activity|UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity|blood-group substance alpha-acetyltransferase activity|blood-group substance A-dependent acetylgalactosaminyltransferase activity|fucosylgalactose alpha-N-acetylgalactosaminyltransferase activity|histo-blood group A transferase activity|fucosylgalactose acetylgalactosaminyltransferase activity|UDP-GalNAc:Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase activity|fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity|alpha-3-N-acetylgalactosaminyltransferase activity|histo-blood group A acetylgalactosaminyltransferase activity											MetaCyc:2.4.1.40-RXN|RHEA:19021|Reactome:R-HSA-9034042|EC:2.4.1.40|Reactome:R-HSA-9033959		molecular_function											owl:Class	
GO:0019501	biolink:NamedThing	arsonoacetate catabolic process	The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom.	got7fsn_ti	arsonoacetate degradation|arsonoacetate breakdown|arsonoacetate catabolism											MetaCyc:P482-PWY		biological_process											owl:Class	
GO:0072482	biolink:NamedThing	response to mitotic cell cycle spindle orientation checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling.	got7fsn_ti	response to signal involved in mitotic cell cycle spindle orientation checkpoint|mitotic cell cycle spindle orientation checkpoint effector process						mah	2010-12-09T12:11:56Z						biological_process											owl:Class	
GO:0072476	biolink:NamedThing	response to mitotic spindle checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling.	got7fsn_ti	response to mitotic cell cycle spindle checkpoint signaling|mitotic cell cycle spindle checkpoint effector process|response to signal involved in mitotic cell cycle spindle checkpoint						mah	2010-12-09T11:50:09Z						biological_process											owl:Class	
GO:0072167	biolink:NamedThing	specification of mesonephric tubule identity	The process in which the tubules of the mesonephros acquire their identity.	got7fsn_ti							mah	2010-02-26T01:51:03Z						biological_process											owl:Class	
GO:0060387	biolink:NamedThing	fertilization envelope	A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.	got7fsn_ti	fertilization membrane													cellular_component											owl:Class	
GO:0102826	biolink:NamedThing	kaempferol-3-glucoside-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol 3-O-glucoside <=> kaempferol 3,7-O-diglucoside + UDP.	got7fsn_ti												MetaCyc:RXN-8270		molecular_function											owl:Class	
GO:0051757	biolink:NamedThing	meiotic sister chromatid separation	The process in which sister chromatids are physically detached from each other during meiosis.	got7fsn_ti	meiotic sister chromatid resolution													biological_process											owl:Class	
GO:0032449	biolink:NamedThing	CBM complex	A protein complex comprising Bcl10, MALT1 and a CARD domain-containing protein (CARD9, CARD10 or CARD11); plays a role in signal transduction during NF-kappaB activation.	got7fsn_ti	CARMA1-BCL10-Malt1 complex	https://github.com/geneontology/go-ontology/issues/21010												cellular_component											owl:Class	
GO:0047971	biolink:NamedThing	guanidinobutyrase activity	Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea.	got7fsn_ti	gamma-guanidinobutyrate amidinohydrolase activity|G-base activity|4-guanidinobutyrate amidinobutyrase activity|gamma-guanidobutyrase activity|guanidinobutyrate ureahydrolase activity|GBH|4-guanidinobutanoate amidinohydrolase activity											MetaCyc:GUANIDINOBUTYRASE-RXN|KEGG_REACTION:R01990|EC:3.5.3.7|RHEA:19501		molecular_function											owl:Class	
GO:0048724	biolink:NamedThing	epistomal sclerite development	The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0019092	biolink:NamedThing	mitochondrial srRNA export from mitochondrion	The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.	got7fsn_ti	mitochondrial srRNA, mitochondrial export|mitochondrial srRNA export from mitochondria|mitochondrial srRNA transport from mitochondrion|mitochondrial srRNA export|export of mitochondrial srRNA|mitochondrial srRNA export out of mitochondrion													biological_process											owl:Class	
GO:0019090	biolink:NamedThing	mitochondrial rRNA export from mitochondrion	The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.	got7fsn_ti	mitochondrial rRNA, mitochondrial export|mitochondrial rRNA transport from mitochondrion|mitochondrial rRNA export from mitochondria|mitochondrial rRNA export|mitochondrial rRNA export out of mitochondrion|export of mitochondrial rRNA													biological_process											owl:Class	
GO:0061046	biolink:NamedThing	regulation of branching involved in lung morphogenesis	Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.	got7fsn_ti							dph	2010-02-25T10:41:38Z						biological_process											owl:Class	
GO:0033444	biolink:NamedThing	AAG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AAG codon.	got7fsn_ti	lysine tRNA				Note that in the standard genetic code, AAG codes for lysine.									molecular_function											owl:Class	
GO:0047782	biolink:NamedThing	coniferin beta-glucosidase activity	Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol.	got7fsn_ti	coniferin beta-D-glucosidase activity|coniferin-hydrolyzing beta-glucosidase activity|coniferin b-glucosidase activity											RHEA:12252|MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN|EC:3.2.1.126		molecular_function											owl:Class	
GO:0052821	biolink:NamedThing	DNA-7-methyladenine glycosylase activity	Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site.	got7fsn_ti							ai	2011-10-28T02:27:39Z				EC:3.2.2.21|MetaCyc:3.2.2.21-RXN		molecular_function											owl:Class	
GO:0075199	biolink:NamedThing	positive regulation of symbiont haustorium neck formation for entry into host	Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0003743	biolink:NamedThing	translation initiation factor activity	Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.	got7fsn_ti											GO:0003744|GO:0003745	Reactome:R-HSA-72722|Reactome:R-HSA-72621|Reactome:R-HSA-72697		molecular_function											owl:Class	
GO:0044173	biolink:NamedThing	host cell endoplasmic reticulum-Golgi intermediate compartment membrane	The lipid bilayer surrounding any of the compartments of the host cell ER-Golgi intermediate compartment system.	got7fsn_ti	host cell ER-Golgi intermediate compartment membrane|host endoplasmic reticulum-Golgi intermediate compartment membrane|host ER-Golgi intermediate compartment membrane						jl	2009-09-04T02:46:13Z						cellular_component											owl:Class	
GO:0090164	biolink:NamedThing	asymmetric Golgi ribbon formation	The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity.	got7fsn_ti							tb	2009-12-08T09:02:45Z						biological_process											owl:Class	
GO:0045059	biolink:NamedThing	positive thymic T cell selection	The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death.	got7fsn_ti	positive thymic T-cell selection|positive thymic T lymphocyte selection|positive thymic T-lymphocyte selection													biological_process											owl:Class	
GO:0050210	biolink:NamedThing	prenyl-diphosphatase activity	Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate.	got7fsn_ti	prenyl-pyrophosphatase activity|prenyl-diphosphate diphosphohydrolase activity|prenylphosphatase activity|prenol pyrophosphatase activity											EC:3.1.7.1|RHEA:21496|MetaCyc:PRENYL-PYROPHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0051995	biolink:NamedThing	Se-methyltransferase activity	Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule.	got7fsn_ti							ai	2010-07-16T04:48:08Z						molecular_function											owl:Class	
GO:0005993	biolink:NamedThing	trehalose catabolic process	The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	got7fsn_ti	mykose catabolism|trehalose degradation|mycose catabolic process|trehalose breakdown|trehalose catabolism|mykose catabolic process|mycose catabolism											MetaCyc:TREDEGLOW-PWY		biological_process											owl:Class	
GO:0071294	biolink:NamedThing	cellular response to zinc ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.	got7fsn_ti	cellular response to zinc						mah	2009-12-10T04:17:10Z						biological_process											owl:Class	
GO:0070012	biolink:NamedThing	oligopeptidase activity	Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.	got7fsn_ti														molecular_function											owl:Class	
GO:0051957	biolink:NamedThing	positive regulation of amino acid transport	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	up-regulation of amino acid transport|activation of amino acid transport|up regulation of amino acid transport|positive regulation of amino acid transmembrane transport|upregulation of amino acid transport|stimulation of amino acid transport													biological_process											owl:Class	
GO:0000769	biolink:NamedThing	syncytium formation by mitosis without cytokinesis	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis.	got7fsn_ti	syncytium formation by mitosis without cell division													biological_process											owl:Class	
GO:0060779	biolink:NamedThing	secondary leaflet morphogenesis	The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet.	got7fsn_ti							dph	2009-07-25T07:19:02Z						biological_process											owl:Class	
GO:0046789	biolink:NamedThing	host cell surface receptor binding	Binding to a receptor on the host cell surface.	got7fsn_ti	cell surface antigen activity, host-interacting|cell surface receptor ligand													molecular_function											owl:Class	
GO:0046812	biolink:NamedThing	host cell surface binding	Binding to the surface of a host cell.	got7fsn_ti														molecular_function											owl:Class	
GO:0033811	biolink:NamedThing	flavonol-3-O-triglucoside O-coumaroyltransferase activity	Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].	got7fsn_ti	4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] 6'''-O-4-coumaroyltransferase activity											MetaCyc:2.3.1.173-RXN|EC:2.3.1.173|RHEA:22160		molecular_function											owl:Class	
GO:1903439	biolink:NamedThing	calcitonin family receptor complex	A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.	got7fsn_ti							pr	2014-09-16T13:25:11Z						cellular_component											owl:Class	
GO:1990422	biolink:NamedThing	glyoxalase (glycolic acid-forming) activity	Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor.	got7fsn_ti							bf	2014-07-21T09:00:21Z						molecular_function											owl:Class	
GO:0004015	biolink:NamedThing	adenosylmethionine-8-amino-7-oxononanoate transaminase activity	Catalysis of the reaction: 8-amino-7-oxononanoate + S-adenosyl-L-methionine(1+) = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate.	got7fsn_ti	DAPA aminotransferase activity|7,8-diaminononanoate aminotransferase activity|adenosyl methionine-8-amino-7-oxononanoate transaminase activity|7,8-diaminononanoate transaminase activity|adenosylmethionine--8-amino-7-oxononanoate aminotransferase activity|7,8-diaminonanoate transaminase activity|adenosylmethionine-8-amino-7-oxononanoate aminotransferase activity|7-keto-8-aminopelargonic acid|S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase activity|7-keto-8-aminopelargonic acid aminotransferase activity|7,8-diaminopelargonic acid aminotransferase activity|DAPA transaminase activity|diaminopelargonate synthase activity|7,8-diamino-pelargonic acid aminotransferase activity											RHEA:16861|MetaCyc:DAPASYN-RXN|KEGG_REACTION:R03231|EC:2.6.1.62		molecular_function											owl:Class	
GO:0038142	biolink:NamedThing	EGFR:ERBB2 complex	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated epidermal growth factor receptor (EGFR/ERBB1). ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.	got7fsn_ti	EGFR:ERBB2 heterodimer|EGF:EGFR:ERBB2 complex						bf	2012-03-30T02:10:38Z						cellular_component											owl:Class	
GO:0098006	biolink:NamedThing	viral DNA genome packaging, headful	The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full.	got7fsn_ti	phage headful packaging				Generalized transducing phages usually use this mode of DNA packaging.		bm	2012-07-18T16:15:09Z						biological_process											owl:Class	
GO:0102745	biolink:NamedThing	dihydrogeranylgeranyl-PP reductase activity	Catalysis of the reaction: H+ + dihydrogeranylgeranyl-PP + NADPH = tetrahydrogeranylgeranyl-PP + NADP.	got7fsn_ti												MetaCyc:RXN-7659		molecular_function											owl:Class	
GO:0050805	biolink:NamedThing	negative regulation of synaptic transmission	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.	got7fsn_ti	down-regulation of synaptic transmission|inhibition of synaptic transmission|down regulation of synaptic transmission|downregulation of synaptic transmission													biological_process											owl:Class	
GO:0050131	biolink:NamedThing	N-methyl-L-amino-acid oxidase activity	Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2.	got7fsn_ti	N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating)|N-methylamino acid oxidase activity											MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN|EC:1.5.3.2|RHEA:11472		molecular_function											owl:Class	
GO:0071066	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of wind	The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.	got7fsn_ti	sensory detection of mechanical stimulus during perception of wind|perception of wind, detection of mechanical stimulus|perception of wind, sensory detection of mechanical stimulus|perception of wind, sensory transduction of mechanical stimulus|detection of mechanical stimulus involved in sensory perception of air flow|detection of wind|sensory transduction of wind|sensory transduction of mechanical stimulus during perception of wind						mah	2009-11-04T02:47:36Z						biological_process											owl:Class	
GO:0030268	biolink:NamedThing	methylenetetrahydromethanopterin dehydrogenase activity	Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420.	got7fsn_ti	5,10-methylenetetrahydromethanopterin dehydrogenase activity|N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity|5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity										GO:0018536	EC:1.5.98.1|MetaCyc:1.5.99.9-RXN|UM-BBD_reactionID:r0348|KEGG_REACTION:R04456|RHEA:16721		molecular_function											owl:Class	
GO:0030310	biolink:NamedThing	poly-N-acetyllactosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.	got7fsn_ti	poly-N-acetyllactosamine degradation|poly-N-acetyllactosamine breakdown|poly-N-acetyllactosamine catabolism													biological_process											owl:Class	
GO:0047694	biolink:NamedThing	barbiturase activity	Catalysis of the reaction: barbiturate + H2O = malonate + urea.	got7fsn_ti	barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming)											MetaCyc:BARBITURASE-RXN|EC:3.5.2.1|RHEA:18653		molecular_function											owl:Class	
GO:0034425	biolink:NamedThing	etioplast envelope	The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	got7fsn_ti														cellular_component											owl:Class	
GO:0070177	biolink:NamedThing	contractile vacuole discharge	The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0021898	biolink:NamedThing	commitment of multipotent stem cells to neuronal lineage in forebrain	The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0014883	biolink:NamedThing	transition between fast and slow fiber	The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.	got7fsn_ti	transition fast-slow fiber|transition fast-slow fibre|transition between fast and slow fibre													biological_process											owl:Class	
GO:0002793	biolink:NamedThing	positive regulation of peptide secretion	Any process that activates or increases the frequency, rate, or extent of peptide secretion.	got7fsn_ti	up regulation of peptide secretion|up-regulation of peptide secretion|upregulation of peptide secretion|activation of peptide secretion|stimulation of peptide secretion													biological_process											owl:Class	
GO:0019513	biolink:NamedThing	lactose catabolic process, using glucoside 3-dehydrogenase	The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13).	got7fsn_ti	lactose breakdown, using glucoside 3-dehydrogenase|lactose degradation, using glucoside 3-dehydrogenase											MetaCyc:LACTOSEUTIL-PWY		biological_process											owl:Class	
GO:0005990	biolink:NamedThing	lactose catabolic process	The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose.	got7fsn_ti	lactose catabolism|lactose breakdown|lactose degradation													biological_process											owl:Class	
GO:0006877	biolink:NamedThing	cellular cobalt ion homeostasis	Any process involved in the maintenance of an internal steady state of cobalt ions at the level of a cell.	got7fsn_ti	cobalt homeostasis													biological_process											owl:Class	
GO:0055068	biolink:NamedThing	cobalt ion homeostasis	Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell.	got7fsn_ti	cobalt homeostasis													biological_process											owl:Class	
GO:0044564	biolink:NamedThing	envenomation resulting in occlusion of the pore of voltage-gated potassium channel in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism.	got7fsn_ti							jl	2012-04-05T04:14:24Z						biological_process											owl:Class	
GO:0033842	biolink:NamedThing	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.	got7fsn_ti	beta1,4-N-acetylgalactosaminyltransferase III activity|beta1,4-N-acetylgalactosaminyltransferase activity|beta4GalNAc-T3|UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity|beta1,4-N-acetylgalactosaminyltransferase IV activity|beta4GalNAc-T4											MetaCyc:2.4.1.244-RXN|RHEA:20493|EC:2.4.1.244		molecular_function											owl:Class	
GO:0060698	biolink:NamedThing	endoribonuclease inhibitor activity	Binds to and stops, prevents or reduces the activity of endoribonuclease.	got7fsn_ti							dph	2009-06-08T02:37:19Z						molecular_function											owl:Class	
GO:0102802	biolink:NamedThing	thebaine 6-O-demethylase activity	Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-8147|RHEA:27477|EC:1.14.11.31		molecular_function											owl:Class	
GO:0043125	biolink:NamedThing	ErbB-3 class receptor binding	Binding to the protein-tyrosine kinase receptor ErbB-3/HER3.	got7fsn_ti	Neu/ErbB-2 receptor activity|HER3 receptor binding													molecular_function											owl:Class	
GO:0043542	biolink:NamedThing	endothelial cell migration	The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.	got7fsn_ti														biological_process											owl:Class	
GO:0071126	biolink:NamedThing	alphaV-beta6 integrin-osteopontin complex	A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin.	got7fsn_ti	ITGAV-ITGB6-SPP1 complex						mah	2009-11-13T02:23:43Z						cellular_component											owl:Class	
GO:0050690	biolink:NamedThing	regulation of defense response to virus by virus	Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism.	got7fsn_ti	regulation by virus of antiviral response|regulation of antiviral response by virus|viral regulation of antiviral response													biological_process											owl:Class	
GO:0070747	biolink:NamedThing	interleukin-35 receptor activity	Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-35 receptor activity|IL-35R						mah	2009-06-23T01:18:09Z						molecular_function											owl:Class	
GO:0018511	biolink:NamedThing	2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity	Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH.	got7fsn_ti	cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase activity											KEGG_REACTION:R05240|UM-BBD_reactionID:r0396|MetaCyc:RXN-665|EC:1.3.1.58|RHEA:23772		molecular_function											owl:Class	
GO:0090087	biolink:NamedThing	regulation of peptide transport	Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2009-10-23T11:21:38Z						biological_process											owl:Class	
GO:0047003	biolink:NamedThing	dTDP-6-deoxy-L-talose 4-dehydrogenase activity	Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH.	got7fsn_ti	TDP-6-deoxy-L-talose dehydrogenase activity|dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase activity|dTDP-6-deoxy-L-talose dehydrogenase (4-reductase)|thymidine diphospho-6-deoxy-L-talose dehydrogenase activity											KEGG_REACTION:R02776|MetaCyc:1.1.1.134-RXN|EC:1.1.1.134|RHEA:23648		molecular_function											owl:Class	
GO:0047787	biolink:NamedThing	delta4-3-oxosteroid 5beta-reductase activity	Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+.	got7fsn_ti	cortisone 5beta-reductase activity|delta(4)-hydrogenase activity|delta4-hydrogenase activity|androstenedione 5-beta-reductase activity|cholestenone 5b-reductase activity|cortisone b-reductase activity|cortisone 5-beta-reductase activity|cortisone beta-reductase activity|cholestenone 5beta-reductase activity|5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity|delta4-5beta-reductase activity|delta(4)-5-beta-reductase activity|steroid 5beta-reductase activity|4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity|cholestenone 5-beta-reductase activity|3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity|delta(4)-3-ketosteroid 5-beta-reductase activity|5-beta-reductase activity|androstenedione 5beta-reductase activity|cortisone delta(4)-5-beta-reductase activity|cortisone delta4-5beta-reductase activity|testosterone 5-beta-reductase activity|5beta-reductase activity|delta4-3-ketosteroid 5beta-reductase activity|testosterone 5beta-reductase activity|3-oxo-Delta(4)-steroid 5-beta-reductase activity|steroid 5-beta-reductase activity|3-oxo-delta4-steroid 5beta-reductase activity|delta4-3-oxosteroid 5-beta-reductase activity										GO:0047752	EC:1.3.1.3|MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN|MetaCyc:CORTISONE-BETA-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0009093	biolink:NamedThing	cysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid.	got7fsn_ti	cysteine degradation|cysteine catabolism|cysteine breakdown											Wikipedia:Cysteine		biological_process											owl:Class	
GO:0035243	biolink:NamedThing	protein-arginine omega-N symmetric methyltransferase activity	Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.	got7fsn_ti	type II PRMT activity|type II protein arginine methyltransferase activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming)				Note that type II protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243'.							EC:2.1.1.320|Reactome:R-HSA-6804383|RESID:AA0069|RHEA:48108|RESID:AA0067		molecular_function											owl:Class	
GO:0048926	biolink:NamedThing	electrosensory lateral line system development	The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0051719	biolink:NamedThing	DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.	got7fsn_ti												Reactome:R-HSA-5334097|Reactome:R-HSA-5334152		molecular_function											owl:Class	
GO:0006629	biolink:NamedThing	lipid metabolic process	The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.	got7fsn_ti	lipid metabolism											Wikipedia:Lipid_metabolism		biological_process											owl:Class	
GO:0106158	biolink:NamedThing	glycero-3-phosphocholine acyltransferase activity	Catalysis of the reaction:acyl-CoA + glycerophosphocholine = CoA + 1-acyl-sn-glycero-3-phosphocholine.	got7fsn_ti	GPACT activity|glycerophosphocholine O-acyltransferase activity|glycero-3-phosphocholine acyltransferase activity	https://github.com/geneontology/go-ontology/issues/16665					hjd	2018-11-26T21:21:03Z				RHEA:58476		molecular_function											owl:Class	
GO:0102537	biolink:NamedThing	ecdysone-phosphate phosphatase activity	Catalysis of the reaction: ecdysone 22-phosphate + H2O <=> ecdysone + hydrogenphosphate.	got7fsn_ti												MetaCyc:RXN-14766		molecular_function											owl:Class	
GO:0042654	biolink:NamedThing	ecdysis-triggering hormone receptor activity	Combining with ecdysis-triggering hormone to initiate a change in cell activity.	got7fsn_ti	ecdysis-triggering hormone binding|ETH receptor													molecular_function											owl:Class	
GO:0102590	biolink:NamedThing	delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+.	got7fsn_ti												MetaCyc:RXN-15351		molecular_function											owl:Class	
GO:0071190	biolink:NamedThing	protocadherin-alpha-v7-protocadherin-gamma-b2 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti	Pcdha7-Pcdhgb4 complex						mah	2009-11-23T04:30:12Z						cellular_component											owl:Class	
GO:0103009	biolink:NamedThing	3-chlorotoluene monooxygenase activity	Catalysis of the reaction: H+ + 3-chlorotoluene + NADH + O2 <=> 3-chlorobenzyl alcohol + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-9908		molecular_function											owl:Class	
GO:0046449	biolink:NamedThing	creatinine metabolic process	The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.	got7fsn_ti	creatinine metabolism													biological_process											owl:Class	
GO:0050028	biolink:NamedThing	L-lysine-lactamase activity	Catalysis of the reaction: L-2-aminohexano-6-lactam + H(2)O = L-lysine.	got7fsn_ti	L-lysinamidase activity|L-alpha-aminocaprolactam hydrolase activity|L-lysine-1,6-lactam lactamhydrolase activity											RHEA:21388|KEGG_REACTION:R00463|EC:3.5.2.11|MetaCyc:L-LYSINE-LACTAMASE-RXN		molecular_function											owl:Class	
GO:0097042	biolink:NamedThing	extrinsic component of fungal-type vacuolar membrane	The component of a fungal-type vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to fungal-type vacuolar membrane						pr	2011-04-19T03:42:39Z						cellular_component											owl:Class	
GO:0000306	biolink:NamedThing	extrinsic component of vacuolar membrane	The component of a vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to vacuolar membrane													cellular_component											owl:Class	
GO:0008313	biolink:NamedThing	gurken-activated receptor activity	Combining with the ligand Gurken to initiate a change in cell activity.	got7fsn_ti	gurken receptor activity													molecular_function											owl:Class	
GO:0039584	biolink:NamedThing	suppression by virus of host protein kinase activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein kinase activity.	got7fsn_ti							bf	2012-05-02T03:04:55Z						biological_process											owl:Class	
GO:0051127	biolink:NamedThing	positive regulation of actin nucleation	Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.	got7fsn_ti	stimulation of actin nucleation|up-regulation of actin nucleation|upregulation of actin nucleation|up regulation of actin nucleation|activation of actin nucleation													biological_process											owl:Class	
GO:0006545	biolink:NamedThing	glycine biosynthetic process	The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.	got7fsn_ti	glycine formation|glycine synthesis|glycine anabolism|glycine biosynthesis											MetaCyc:GLYCINE-SYN2-PWY		biological_process											owl:Class	
GO:0034460	biolink:NamedThing	uropod assembly	The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane.	got7fsn_ti	uropod formation													biological_process											owl:Class	
GO:0001543	biolink:NamedThing	ovarian follicle rupture	Disruption of theca cell layer releasing follicular fluid and/or the oocyte.	got7fsn_ti														biological_process											owl:Class	
GO:1901269	biolink:NamedThing	lipooligosaccharide metabolic process	The chemical reactions and pathways involving lipooligosaccharide.	got7fsn_ti	lipooligosaccharide metabolism						yaf	2012-08-17T14:31:26Z						biological_process											owl:Class	
GO:0006858	biolink:NamedThing	extracellular transport	The transport of substances that occurs outside cells.	got7fsn_ti														biological_process											owl:Class	
GO:0032924	biolink:NamedThing	activin receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	activin receptor signalling pathway													biological_process											owl:Class	
GO:0031945	biolink:NamedThing	positive regulation of glucocorticoid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.	got7fsn_ti	up-regulation of glucocorticoid metabolic process|upregulation of glucocorticoid metabolic process|positive regulation of glucocorticoid metabolism|up regulation of glucocorticoid metabolic process|activation of glucocorticoid metabolic process|stimulation of glucocorticoid metabolic process													biological_process											owl:Class	
GO:0072165	biolink:NamedThing	anterior mesonephric tubule development	The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros.	got7fsn_ti							mah	2010-02-26T01:47:26Z						biological_process											owl:Class	
GO:0003841	biolink:NamedThing	1-acylglycerol-3-phosphate O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.	got7fsn_ti	1-acyl-sn-glycerol-3-phosphate acyltransferase activity|1-acylglycero-3-phosphate acyltransferase activity|1-acyl-sn-glycerol 3-phosphate acyltransferase activity|1-acyl-sn-glycero-3-phosphate acyltransferase activity|lysophosphatidate acyltransferase activity|1-acylglycerophosphate acyltransferase activity|acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase activity|1-acylglycerolphosphate acyltransferase activity|lysophosphatidic acid-acyltransferase activity										GO:0004469	MetaCyc:RXN-1623|Reactome:R-HSA-1482667|Reactome:R-HSA-1482894|Reactome:R-HSA-1482689|Reactome:R-HSA-1482598|Reactome:R-HSA-75885|RHEA:19709|Reactome:R-HSA-1482547|Reactome:R-HSA-1482548|Reactome:R-HSA-1482539|Reactome:R-HSA-8849345|Reactome:R-HSA-1482636|EC:2.3.1.51		molecular_function											owl:Class	
GO:0034832	biolink:NamedThing	geranial dehydrogenase activity	Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r1164		molecular_function											owl:Class	
GO:0044298	biolink:NamedThing	cell body membrane	The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections.	got7fsn_ti	cell soma membrane						jl	2010-02-05T10:39:23Z						cellular_component											owl:Class	
GO:0042859	biolink:NamedThing	chrysobactin catabolic process	The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).	got7fsn_ti	chrysobactin breakdown|chrysobactin degradation|chrysobactin catabolism													biological_process											owl:Class	
GO:0046215	biolink:NamedThing	siderophore catabolic process	The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.	got7fsn_ti	siderophore catabolism|siderochrome catabolism|siderophore degradation|siderophore breakdown													biological_process											owl:Class	
GO:0008389	biolink:NamedThing	coumarin 7-hydroxylase activity	Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+.	got7fsn_ti	cytochrome P450 CYP2A5											Reactome:R-HSA-211881|Reactome:R-HSA-76453		molecular_function											owl:Class	
GO:0050558	biolink:NamedThing	maltose epimerase activity	Catalysis of the reaction: alpha-maltose = beta-maltose.	got7fsn_ti	maltose 1-epimerase activity											MetaCyc:5.1.3.21-RXN|RHEA:21228|KEGG_REACTION:R07319|EC:5.1.3.21		molecular_function											owl:Class	
GO:0015652	biolink:NamedThing	quaternary ammonium group:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in).	got7fsn_ti	quaternary ammonium group:hydrogen symporter activity													molecular_function											owl:Class	
GO:1990161	biolink:NamedThing	DnaB helicase complex	A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair.	got7fsn_ti	DnaB hexamer						bhm	2013-08-02T15:55:48Z						cellular_component											owl:Class	
GO:0002754	biolink:NamedThing	intracellular endosomal pattern recognition receptor signaling pathway	Any series of molecular signals generated as a consequence of an intracellular vesicle pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.	got7fsn_ti	intracellular vesicle pattern recognition receptor signaling pathway|intracellular vesicle PAMP receptor signaling pathway|intracellular vesicle PRR signaling pathway|intracellular vesicle pathogen receptor signaling pathway|intracellular vesicle pattern recognition receptor signalling pathway	https://github.com/geneontology/go-ontology/issues/18679												biological_process											owl:Class	
GO:0045450	biolink:NamedThing	bicoid mRNA localization	Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.	got7fsn_ti	establishment and maintenance of bicoid mRNA localization|bicoid mRNA localisation													biological_process											owl:Class	
GO:0060811	biolink:NamedThing	intracellular mRNA localization involved in anterior/posterior axis specification	Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis.	got7fsn_ti	intracellular mRNA localisation involved in anterior/posterior axis specification						dph	2009-08-07T09:26:22Z						biological_process											owl:Class	
GO:0043585	biolink:NamedThing	nose morphogenesis	The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).	got7fsn_ti	nasus morphogenesis													biological_process											owl:Class	
GO:0031975	biolink:NamedThing	envelope	A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.	got7fsn_ti														cellular_component											owl:Class	
GO:0050843	biolink:NamedThing	S-adenosylmethionine catabolic process	The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.	got7fsn_ti	S-adenosyl methionine catabolic process|SAM catabolic process|S-adenosylmethionine breakdown|S-adenosylmethionine catabolism|S-adenosylmethionine degradation|S-adenosyl methionine catabolism													biological_process											owl:Class	
GO:0048377	biolink:NamedThing	lateral mesodermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	lateral mesoderm cell fate specification|lateral plate mesodermal cell fate specification|lateral plate mesoderm cell fate specification													biological_process											owl:Class	
GO:0072522	biolink:NamedThing	purine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.	got7fsn_ti	purine-containing compound biosynthesis|purine-containing compound anabolism|purine and derivative biosynthetic process|purine-containing compound formation|purine-containing compound synthesis						mah	2011-01-04T03:15:29Z						biological_process											owl:Class	
GO:0034122	biolink:NamedThing	negative regulation of toll-like receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.	got7fsn_ti	negative regulation of TLR signaling pathway|negative regulation of toll-like receptor signalling pathway													biological_process											owl:Class	
GO:0046990	biolink:NamedThing	N-hydroxyarylamine O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.	got7fsn_ti	arylhydroxamate N,O-acetyltransferase activity|N-hydroxy-2-aminofluorene-O-acetyltransferase activity|acetyl-CoA:N-hydroxyarylamine O-acetyltransferase activity											MetaCyc:2.3.1.118-RXN|EC:2.3.1.118|RHEA:20277		molecular_function											owl:Class	
GO:0001725	biolink:NamedThing	stress fiber	A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.	got7fsn_ti	stress fibre|actin cable													cellular_component											owl:Class	
GO:0047078	biolink:NamedThing	3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity	Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate.	got7fsn_ti	1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity|3-hydroxy-4(1H)-one, 2,4-dioxygenase activity|quinoline-3,4-diol 2,4-dioxygenase activity|3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase activity|3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)|(1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity											RHEA:17949|EC:1.13.11.47|MetaCyc:1.13.11.47-RXN		molecular_function											owl:Class	
GO:1900601	biolink:NamedThing	endocrocin catabolic process	The chemical reactions and pathways resulting in the breakdown of endocrocin.	got7fsn_ti	endocrocin degradation|endocrocin breakdown|endocrocin catabolism						di	2012-05-15T06:57:34Z						biological_process											owl:Class	
GO:0052615	biolink:NamedThing	ent-kaurene oxidase activity	Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol.	got7fsn_ti												RHEA:32323|MetaCyc:1.14.13.78-RXN|EC:1.14.14.86		molecular_function											owl:Class	
GO:2000908	biolink:NamedThing	positive regulation of glucomannan catabolic process	Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process.	got7fsn_ti	positive regulation of glucomannan catabolism						tt	2011-07-29T01:13:30Z						biological_process											owl:Class	
GO:2000996	biolink:NamedThing	positive regulation of mannan catabolic process	Any process that activates or increases the frequency, rate or extent of mannan catabolic process.	got7fsn_ti	positive regulation of mannan catabolism|positive regulation of mannan breakdown|positive regulation of mannan degradation						tt	2011-08-08T03:19:18Z						biological_process											owl:Class	
GO:0007429	biolink:NamedThing	secondary branching, open tracheal system	Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster.	got7fsn_ti	secondary tracheal branching													biological_process											owl:Class	
GO:0000176	biolink:NamedThing	nuclear exosome (RNase complex)	A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.	got7fsn_ti	nuclear exosome multienzyme ribonuclease complex|eukaryotic exosome multienzyme ribonuclease complex|nuclear exosome (ribonuclease complex)													cellular_component											owl:Class	
GO:0034493	biolink:NamedThing	melanosome lumen	The volume enclosed by the melanosome membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0046354	biolink:NamedThing	mannan biosynthetic process	The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.	got7fsn_ti	mannan biosynthesis|mannan synthesis|mannan anabolism|mannan formation													biological_process											owl:Class	
GO:0035159	biolink:NamedThing	regulation of tube length, open tracheal system	Ensuring that a tube in an open tracheal system is of the correct length.	got7fsn_ti	regulation of tracheal tube length|tracheal tube elongation													biological_process											owl:Class	
GO:0035151	biolink:NamedThing	regulation of tube size, open tracheal system	Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.	got7fsn_ti	regulation of tracheal tube size													biological_process											owl:Class	
GO:0031244	biolink:NamedThing	extrinsic component of cell outer membrane	The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to cell outer membrane													cellular_component											owl:Class	
GO:0046720	biolink:NamedThing	citric acid secretion	The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue.	got7fsn_ti	citrate secretion													biological_process											owl:Class	
GO:0070086	biolink:NamedThing	ubiquitin-dependent endocytosis	Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.	got7fsn_ti	ubiquitin-mediated endocytosis													biological_process											owl:Class	
GO:0002010	biolink:NamedThing	excitation of vasomotor center by baroreceptor signaling	The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.	got7fsn_ti	excitation of vasomotor center by baroreceptor signalling													biological_process											owl:Class	
GO:0103101	biolink:NamedThing	UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 7-methylthioheptylhydroximate <=> H+ + 6-methylthiohexyldesulfoglucosinolate + UDP.	got7fsn_ti												MetaCyc:RXNQT-4326|EC:2.4.1.195		molecular_function											owl:Class	
GO:0032233	biolink:NamedThing	positive regulation of actin filament bundle assembly	Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.	got7fsn_ti	up-regulation of actin filament bundle formation|up regulation of actin filament bundle formation|activation of actin filament bundle formation|upregulation of actin filament bundle formation|stimulation of actin filament bundle formation													biological_process											owl:Class	
GO:0032428	biolink:NamedThing	beta-N-acetylgalactosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.	got7fsn_ti												MetaCyc:3.2.1.53-RXN|EC:3.2.1.53		molecular_function											owl:Class	
GO:0004563	biolink:NamedThing	beta-N-acetylhexosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.	got7fsn_ti	beta-D-hexosaminidase activity|hexosaminidase A|beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase activity|N-acetyl-beta-glucosaminidase activity|beta-N-acetyl-D-hexosaminidase activity|beta-hexosaminidase activity|N-acetyl-beta-hexosaminidase activity|beta-D-N-acetylhexosaminidase activity|beta-acetylhexosaminidinase activity|beta-acetylaminodeoxyhexosidase activity|N-acetyl-beta-D-hexosaminidase activity|N-acetylhexosaminidase activity											Reactome:R-HSA-9035976|Reactome:R-HSA-2162225|Reactome:R-HSA-1605595|Reactome:R-HSA-3662344|Reactome:R-HSA-9638075|Reactome:R-HSA-9035978|Reactome:R-HSA-9035983|EC:3.2.1.52|Reactome:R-HSA-1638053|Reactome:R-HSA-2105001|Reactome:R-HSA-1605632|MetaCyc:3.2.1.52-RXN|Reactome:R-HSA-3656259|Reactome:R-HSA-9638076|Reactome:R-HSA-9035982|Reactome:R-HSA-9638078		molecular_function											owl:Class	
GO:0050536	biolink:NamedThing	(S)-N-acetyl-1-phenylethylamine hydrolase activity	Catalysis of the reaction: N-acetylphenylethylamine + H(2)O = acetate + phenylethylamine.	got7fsn_ti	(S)-N-acetylphenylethylamine:H2O hydrolase activity|(S)-N-acetyl-1-phenylethylamine amidohydrolase activity											RHEA:23952|EC:3.5.1.85|KEGG_REACTION:R07301|MetaCyc:3.5.1.85-RXN		molecular_function											owl:Class	
GO:0072586	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity	Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.	got7fsn_ti							mah	2011-02-09T05:31:50Z						molecular_function											owl:Class	
GO:0047758	biolink:NamedThing	ATP:2-methylpropanoate phosphotransferase activity	Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H(+).	got7fsn_ti	branched-chain fatty acid kinase activity|isobutyrate kinase activity|branched-chain-fatty-acid kinase activity|ATP:branched-chain-fatty-acid 1-phosphotransferase activity|ATP:2-methylpropanoate kinase activity|ATP:2-methylpropanoate 1-phosphotransferase activity|ATP:isobutyrate 1-phosphotransferase activity											RHEA:24156|EC:2.7.2.14|KEGG_REACTION:R04002|MetaCyc:BRANCHED-CHAIN-FATTY-ACID-KINASE-RXN		molecular_function											owl:Class	
GO:0044730	biolink:NamedThing	bone sialoprotein binding	Binding to a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin.	got7fsn_ti	bone sialoprotein II binding						jl	2012-11-06T13:05:56Z				InterPro:IPR008412		molecular_function											owl:Class	
GO:0050559	biolink:NamedThing	copalyl diphosphate synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate.	got7fsn_ti	diterpene cyclase activity|(+)-copalyl-diphosphate lyase (decyclizing)											MetaCyc:RXN-4861|EC:5.5.1.12|RHEA:24316|KEGG_REACTION:R06298		molecular_function											owl:Class	
GO:0004108	biolink:NamedThing	citrate (Si)-synthase activity	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group.	got7fsn_ti	citrate synthetase activity|citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity|citrate synthase activity|citrate oxaloacetate-lyase, CoA-acetylating activity|citric-condensing enzyme activity|condensing enzyme activity|citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]|citrate condensing enzyme activity|citrogenase activity|oxaloacetate transacetase activity|(R)-citric synthase activity|citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)|citric synthase activity|oxalacetic transacetase activity|acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]				Note that this function was formerly EC:4.1.3.7.							EC:2.3.3.1|Reactome:R-HSA-70975|MetaCyc:CITSYN-RXN		molecular_function											owl:Class	
GO:0140517	biolink:NamedThing	protein-RNA adaptor activity	The binding activity of a protein that brings together another protein and an RNA, permitting those molecules to function in a coordinated way.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19409					pg	2020-09-11T09:12:05Z						molecular_function											owl:Class	
GO:0008957	biolink:NamedThing	phenylacetaldehyde dehydrogenase activity	Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+.	got7fsn_ti	phenylacetaldehyde:NAD+ oxidoreductase activity											RHEA:21392|EC:1.2.1.39|UM-BBD_reactionID:r0035|MetaCyc:PHENDEHYD-RXN		molecular_function											owl:Class	
GO:0046860	biolink:NamedThing	glycosome membrane	The lipid bilayer surrounding a glycosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0032243	biolink:NamedThing	negative regulation of nucleoside transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	downregulation of nucleoside transport|inhibition of nucleoside transport|down-regulation of nucleoside transport|down regulation of nucleoside transport													biological_process											owl:Class	
GO:0019757	biolink:NamedThing	glycosinolate metabolic process	The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.	got7fsn_ti	glycosinolate metabolism													biological_process											owl:Class	
GO:0097203	biolink:NamedThing	phagocytic cup lip	The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome.	got7fsn_ti							pr	2011-12-21T10:26:41Z						cellular_component											owl:Class	
GO:0035999	biolink:NamedThing	tetrahydrofolate interconversion	The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.	got7fsn_ti							bf	2011-09-02T01:35:49Z				UniPathway:UPA00193|MetaCyc:PWY-2201		biological_process											owl:Class	
GO:0098870	biolink:NamedThing	action potential propagation	The propagation of an action potential along the plane of an excitable membrane.  Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold.	got7fsn_ti														biological_process											owl:Class	
GO:0061563	biolink:NamedThing	trigeminal ganglion structural organization	The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	trigeminal ganglia organization						dph	2013-07-10T09:12:11Z						biological_process											owl:Class	
GO:0043830	biolink:NamedThing	thiol-driven fumarate reductase activity	Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide.	got7fsn_ti												EC:1.3.99.-		molecular_function											owl:Class	
GO:0047325	biolink:NamedThing	inositol tetrakisphosphate 1-kinase activity	Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.	got7fsn_ti	inositol 3,4,5,6-tetrakisphosphate 1-kinase activity|1D-myo-inositol-trisphosphate 5-kinase activity|ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase activity|inositol-tetrakisphosphate 1-kinase activity|1D-myo-inositol-tetrakisphosphate 1-kinase activity|inositol-trisphosphate 6-kinase activity|inositol-trisphosphate 5-kinase activity|1D-myo-inositol-trisphosphate 6-kinase activity											Reactome:R-HSA-994137|Reactome:R-HSA-1855162|EC:2.7.1.134|RHEA:12452|MetaCyc:2.7.1.134-RXN		molecular_function											owl:Class	
GO:0034548	biolink:NamedThing	N-cyclopropylammeline deaminase activity	Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3.	got7fsn_ti												UM-BBD_reactionID:r0826|MetaCyc:RXN-8019		molecular_function											owl:Class	
GO:0070770	biolink:NamedThing	alphaIIb-beta3 integrin-CD47-FAK complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.	got7fsn_ti	ITGA2b-ITGB3-CD47-FAK complex						mah	2009-06-29T05:43:59Z						cellular_component											owl:Class	
GO:0099640	biolink:NamedThing	axo-dendritic protein transport	The directed movement of proteins along microtubules in neuron projections.	got7fsn_ti	axonal protein transport													biological_process											owl:Class	
GO:0048323	biolink:NamedThing	axial mesodermal cell fate determination	The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	axial mesoderm cell fate determination													biological_process											owl:Class	
GO:0085042	biolink:NamedThing	periarbuscular membrane	A host-derived membrane surrounding the symbiont arbuscule during symbiosis.	got7fsn_ti					See also: arbuscule ; GO:0085041.		jl	2010-07-27T04:31:37Z						cellular_component											owl:Class	
GO:0018721	biolink:NamedThing	trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity	Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate.	got7fsn_ti	trans-9R,10R-dihydrodiolphenanthrene sulphotransferase activity											UM-BBD_reactionID:r0559		molecular_function											owl:Class	
GO:0120198	biolink:NamedThing	positive regulation of imaginal disc-derived wing size	Any process that increases the size of an imaginal disc-derived wing.	got7fsn_ti							krc	2019-04-30T21:47:06Z						biological_process											owl:Class	
GO:0099582	biolink:NamedThing	neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration	Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol.	got7fsn_ti	neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels													molecular_function											owl:Class	
GO:0061499	biolink:NamedThing	outer plaque of mitotic spindle pole body	One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm.	got7fsn_ti							dph	2012-12-11T09:18:43Z						cellular_component											owl:Class	
GO:0018603	biolink:NamedThing	nitrobenzene 1,2-dioxygenase activity	Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol.	got7fsn_ti												UM-BBD_reactionID:r0306|EC:1.14.12.-		molecular_function											owl:Class	
GO:0031361	biolink:NamedThing	integral component of thylakoid membrane	The component of the thylakoid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to thylakoid membrane													cellular_component											owl:Class	
GO:0030317	biolink:NamedThing	flagellated sperm motility	The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.	got7fsn_ti	sperm flagellum movement involved in flagellated sperm movement|flagellated sperm movement|sperm movement|sperm motility|sperm flagellum movement involved in flagellated sperm motility|sperm flagellum movement										GO:1905419|GO:0097724	Wikipedia:Sperm_motility		biological_process											owl:Class	
GO:0060294	biolink:NamedThing	cilium movement involved in cell motility	Movement of cilia mediated by motor proteins that contributes to the movement of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0061445	biolink:NamedThing	endocardial cushion cell fate commitment	The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell.	got7fsn_ti							dph	2012-03-13T09:11:03Z						biological_process											owl:Class	
GO:0031433	biolink:NamedThing	telethonin binding	Binding to telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase.	got7fsn_ti														molecular_function											owl:Class	
GO:0034473	biolink:NamedThing	U1 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U1 snRNA molecule.	got7fsn_ti	U1 snRNA 3' end processing													biological_process											owl:Class	
GO:0038097	biolink:NamedThing	positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway	An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.	got7fsn_ti	Fc epsilon RI-dependent mast cell activation|positive regulation of mast cell activation by Fc-epsilon receptor signalling pathway|Fc epsilon RI-mediated mast cell activation						bf	2012-02-16T05:30:09Z						biological_process											owl:Class	
GO:0009702	biolink:NamedThing	L-arabinokinase activity	Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H(+).	got7fsn_ti	ATP:L-arabinose 1-phosphotransferase activity|L-arabinokinase (phosphorylating)											EC:2.7.1.46|RHEA:20153|MetaCyc:L-ARABINOKINASE-RXN|KEGG_REACTION:R01754		molecular_function											owl:Class	
GO:0070356	biolink:NamedThing	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof).	got7fsn_ti	SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2)|STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2 complex													cellular_component											owl:Class	
GO:0072339	biolink:NamedThing	cellular lactam biosynthetic process	The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	got7fsn_ti	cellular lactam synthesis|cellular lactam anabolism|cellular lactam biosynthesis|cellular lactam formation						mah	2010-11-04T04:33:01Z						biological_process											owl:Class	
GO:0150063	biolink:NamedThing	visual system development	The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.	got7fsn_ti	visual pathway development|optic pathway development						bc	2018-07-23T10:31:58Z						biological_process											owl:Class	
GO:0099605	biolink:NamedThing	regulation of action potential firing rate	Any process that regulates the frequency of action potentials in a spike train.	got7fsn_ti														biological_process											owl:Class	
GO:0005760	biolink:NamedThing	gamma DNA polymerase complex	A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA.	got7fsn_ti														cellular_component											owl:Class	
GO:0050167	biolink:NamedThing	pantothenoylcysteine decarboxylase activity	Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO(2).	got7fsn_ti	N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase (pantetheine-forming)|N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase activity|pantothenylcysteine decarboxylase activity|N-((R)-pantothenoyl)-L-cysteine carboxy-lyase activity											EC:4.1.1.30|RHEA:15077|MetaCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN|KEGG_REACTION:R02972		molecular_function											owl:Class	
GO:0002400	biolink:NamedThing	tolerance induction in nasopharyngeal-associated lymphoid tissue	Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT).	got7fsn_ti	tolerance induction in NALT|nasal tolerance													biological_process											owl:Class	
GO:0101010	biolink:NamedThing	pulmonary blood vessel remodeling	The reorganization or renovation of existing pulmonary blood vessels.	got7fsn_ti														biological_process											owl:Class	
GO:0051306	biolink:NamedThing	mitotic sister chromatid separation	The process in which sister chromatids are physically detached from each other during mitosis.	got7fsn_ti	mitotic sister chromatid resolution|mitotic chromosome separation|sister chromatid separation during mitosis|chromosome separation during mitosis													biological_process											owl:Class	
GO:0051304	biolink:NamedThing	chromosome separation	The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).	got7fsn_ti	rDNA separation|chromatid release										GO:0034500			biological_process											owl:Class	
GO:0051204	biolink:NamedThing	protein insertion into mitochondrial membrane	The process that results in the incorporation of a protein into a mitochondrial membrane.	got7fsn_ti	integral mitochondrial membrane protein positioning|positioning of protein in mitochondrial membrane|localization of protein in mitochondrial membrane|protein-mitochondrion membrane insertion|protein insertion into mitochondrion membrane|protein-mitochondrial membrane insertion|integral mitochondrial membrane protein localization	https://github.com/geneontology/go-ontology/issues/15800												biological_process											owl:Class	
GO:0061329	biolink:NamedThing	Malpighian tubule principal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.	got7fsn_ti							dph	2010-09-28T01:26:33Z						biological_process											owl:Class	
GO:0003049	biolink:NamedThing	regulation of systemic arterial blood pressure by capillary fluid shift	The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.	got7fsn_ti	blood pressure regulation by capillary fluid shift													biological_process											owl:Class	
GO:0044378	biolink:NamedThing	non-sequence-specific DNA binding, bending	The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	got7fsn_ti	DNA bending involving non-sequence-specific DNA binding						jl	2011-12-08T02:02:13Z						molecular_function											owl:Class	
GO:0090376	biolink:NamedThing	seed trichome differentiation	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.	got7fsn_ti	cotton fiber development|seed hair differentiation|seed trichome development						tb	2010-09-15T02:07:10Z						biological_process											owl:Class	
GO:0043240	biolink:NamedThing	Fanconi anaemia nuclear complex	A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.	got7fsn_ti	FA core complex|FA complex|Fanconi anaemia complex|FA nuclear complex													cellular_component											owl:Class	
GO:0008030	biolink:NamedThing	neuronal pentraxin receptor activity	Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	neuronal pentaxin receptor													molecular_function											owl:Class	
GO:0002792	biolink:NamedThing	negative regulation of peptide secretion	Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.	got7fsn_ti	down regulation of peptide secretion|down-regulation of peptide secretion|inhibition of peptide secretion|downregulation of peptide secretion													biological_process											owl:Class	
GO:0008951	biolink:NamedThing	palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity	Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein].	got7fsn_ti	palmitoleoyl ACP-dependent acyltransferase activity											RHEA:44012|MetaCyc:PALMITOTRANS-RXN		molecular_function											owl:Class	
GO:0045516	biolink:NamedThing	interleukin-19 receptor binding	Binding to an interleukin-19 receptor.	got7fsn_ti	IL-19|interleukin-19 receptor ligand													molecular_function											owl:Class	
GO:0030340	biolink:NamedThing	hyaluronate lyase activity	Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine.	got7fsn_ti	glucuronoglycosaminoglycan lyase activity|spreading factor activity|hyaluronidase activity|mucinase activity|hyaluronidase [but cf. EC:3.2.1.35 (hyalurononglucosaminidase) and EC:3.2.1.36 (hyaluronoglucuronidase)]											EC:4.2.2.1|RHEA:50240|MetaCyc:HYALURONATE-LYASE-RXN		molecular_function											owl:Class	
GO:0050552	biolink:NamedThing	(4S)-limonene synthase activity	Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate.	got7fsn_ti	(-)-(4S)-limonene synthase activity|geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-(4S)-limonene-forming]|geranyldiphosphate diphosphate lyase (limonene forming)|4S-(-)-limonene synthase activity|geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]											EC:4.2.3.16|MetaCyc:4.2.3.16-RXN|RHEA:12869		molecular_function											owl:Class	
GO:0010014	biolink:NamedThing	meristem initiation	Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0018311	biolink:NamedThing	peptidyl-N4-hydroxymethyl-L-asparagine biosynthetic process from peptidyl-asparagine	The chemical reactions and pathways resulting in the formation of N4-hydroxymethyl-L-asparagine from other compounds, including peptidyl-asparagine.	got7fsn_ti	peptidyl-N4-hydroxymethyl-L-asparagine anabolism from peptidyl-asparagine|peptidyl-N4-hydroxymethyl-L-asparagine formation from peptidyl-asparagine|peptidyl-N4-hydroxymethyl-L-asparagine synthesis from peptidyl-asparagine											RESID:AA0236		biological_process											owl:Class	
GO:0006798	biolink:NamedThing	polyphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid.	got7fsn_ti	polyphosphate catabolism|polyphosphate degradation|polyphosphate breakdown													biological_process											owl:Class	
GO:0005544	biolink:NamedThing	calcium-dependent phospholipid binding	Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.	got7fsn_ti														molecular_function											owl:Class	
GO:0005543	biolink:NamedThing	phospholipid binding	Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.	got7fsn_ti														molecular_function											owl:Class	
GO:0004516	biolink:NamedThing	nicotinate phosphoribosyltransferase activity	Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate.	got7fsn_ti	nicotinic acid phosphoribosyltransferase activity|niacin ribonucleotidase activity|nicotinic acid mononucleotide pyrophosphorylase activity|nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|nicotinic acid mononucleotide glycohydrolase activity											Reactome:R-HSA-197186|RHEA:36163|EC:6.3.4.21|KEGG_REACTION:R01724|MetaCyc:NICOTINATEPRIBOSYLTRANS-RXN		molecular_function											owl:Class	
GO:0071770	biolink:NamedThing	DIM/DIP cell wall layer assembly	The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.	got7fsn_ti	PDIM cell wall layer assembly|DIM cell wall layer assembly|DIM/DIP cell wall layer biogenesis						mah	2010-03-29T04:47:19Z						biological_process											owl:Class	
GO:0005476	biolink:NamedThing	carnitine:acyl carnitine antiporter activity	Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial).	got7fsn_ti	carnitine/acyl carnitine carrier activity|carnitine:acyl carnitine carrier activity|fatty acyl carnitine carrier													molecular_function											owl:Class	
GO:0030731	biolink:NamedThing	guanidinoacetate N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+).	got7fsn_ti	guanidinoacetate methyltransferase activity|GA methylpherase activity|methionine-guanidinoacetic transmethylase activity|guanidoacetate methyltransferase activity|guanidinoacetate transmethylase activity|S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase activity											KEGG_REACTION:R01883|MetaCyc:GUANIDINOACETATE-N-METHYLTRANSFERASE-RXN|RHEA:10656|EC:2.1.1.2		molecular_function											owl:Class	
GO:1900556	biolink:NamedThing	emericellamide catabolic process	The chemical reactions and pathways resulting in the breakdown of emericellamide.	got7fsn_ti	emericellamide breakdown|emericellamide catabolism|emericellamide degradation						di	2012-05-15T01:33:07Z						biological_process											owl:Class	
GO:1900610	biolink:NamedThing	F-9775A catabolic process	The chemical reactions and pathways resulting in the breakdown of F-9775A.	got7fsn_ti	F-9775A degradation|F-9775A breakdown|F-9775A catabolism						di	2012-05-15T07:02:49Z						biological_process											owl:Class	
GO:0018503	biolink:NamedThing	trans-1,2-dihydrodiolphenanthrene dehydrogenase activity	Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene.	got7fsn_ti												UM-BBD_reactionID:r0574		molecular_function											owl:Class	
GO:0042863	biolink:NamedThing	pyochelin metabolic process	The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).	got7fsn_ti	pyochelin metabolism													biological_process											owl:Class	
GO:0039509	biolink:NamedThing	suppression by virus of host pattern recognition receptor activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host pattern recognition receptor. A pattern recognition receptor combines with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity.	got7fsn_ti	down-regulation by virus of host pattern recognition receptor activity|down regulation by virus of host pattern recognition receptor activity|viral inhibition of host pattern recognition receptor activity|negative regulation by virus of host pattern recognition receptor activity|suppression by virus of host pattern recognition receptor function|inhibition by virus of host pattern recognition receptor activity						bf	2011-06-02T03:11:23Z						biological_process											owl:Class	
GO:0039508	biolink:NamedThing	suppression by virus of host receptor activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host receptor.	got7fsn_ti	down-regulation by virus of host receptor activity|inhibition by virus of host receptor activity|viral inhibition of host receptor|downregulation by virus of host receptor activity|negative regulation by virus of host receptor activity|suppression by virus of host receptor function						bf	2011-06-02T03:09:37Z						biological_process											owl:Class	
GO:0046989	biolink:NamedThing	galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids.	got7fsn_ti														molecular_function											owl:Class	
GO:0034366	biolink:NamedThing	spherical high-density lipoprotein particle	A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).	got7fsn_ti	mature HDL|spherical HDL|mature high-density lipoprotein particle													cellular_component											owl:Class	
GO:0035797	biolink:NamedThing	tellurite methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride).	got7fsn_ti	tellurite methylase activity|SAM-dependent tellurite methyltransferase activity|S-adenosyl-L-methionine-dependent tellurite methyltransferase activity						bf	2011-04-14T01:06:19Z						molecular_function											owl:Class	
GO:0000139	biolink:NamedThing	Golgi membrane	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.	got7fsn_ti														cellular_component											owl:Class	
GO:0070714	biolink:NamedThing	RNA guanosine-uridine insertion	The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide.	got7fsn_ti	RNA GU insertion						mah	2009-06-08T05:33:20Z						biological_process											owl:Class	
GO:0043616	biolink:NamedThing	keratinocyte proliferation	The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.	got7fsn_ti														biological_process											owl:Class	
GO:0120133	biolink:NamedThing	negative regulation of actin cortical patch assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches.	got7fsn_ti	downregulation of actin cortical patch assembly|inhibition of actin cortical patch assembly|down-regulation of actin cortical patch assembly|down regulation of actin cortical patch assembly						krc	2018-02-20T16:23:53Z						biological_process											owl:Class	
GO:0047031	biolink:NamedThing	diethyl 2-methyl-3-oxosuccinate reductase activity	Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-3-oxosuccinate + H(+) + NADPH.	got7fsn_ti	diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase activity											EC:1.1.1.229|RHEA:21008|KEGG_REACTION:R04387|MetaCyc:1.1.1.229-RXN		molecular_function											owl:Class	
GO:0061595	biolink:NamedThing	6-deoxy-6-sulfofructose-1-phosphate aldolase activity	Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate.	got7fsn_ti							dph	2014-02-10T10:05:27Z						molecular_function											owl:Class	
GO:0102122	biolink:NamedThing	gibberellin A34 carboxyl methyltransferase activity	Catalysis of the reaction: gibberellin A34 + S-adenosyl-L-methionine  = gibberellin A34 methyl ester + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:36127|MetaCyc:RXN-11384		molecular_function											owl:Class	
GO:0031733	biolink:NamedThing	CCR8 chemokine receptor binding	Binding to a CCR8 chemokine receptor.	got7fsn_ti	CCR8 chemokine receptor ligand													molecular_function											owl:Class	
GO:0045050	biolink:NamedThing	protein insertion into ER membrane by stop-transfer membrane-anchor sequence	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix.	got7fsn_ti	protein-ER insertion by stop-transfer membrane-anchor sequence|protein insertion into ER membrane, stop-transfer membrane-anchor sequence mediated|protein-endoplasmic reticulum insertion by stop-transfer membrane-anchor sequence|protein insertion into endoplasmic reticulum membrane by stop-transfer membrane-anchor sequence|stop-transfer membrane-anchor sequence mediated protein insertion into ER membrane													biological_process											owl:Class	
GO:0097542	biolink:NamedThing	ciliary tip	Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.	got7fsn_ti	cilial tip|flagellum tip|cilium tip|flagellar tip				Note that cilia and eukaryotic flagella are deemed to be equivalent.		pr	2013-12-12T11:12:22Z						cellular_component											owl:Class	
GO:1990955	biolink:NamedThing	G-rich single-stranded DNA binding	Binding to G-rich, single-stranded DNA.	got7fsn_ti							hjd	2016-05-13T17:44:28Z						molecular_function											owl:Class	
GO:0102219	biolink:NamedThing	phosphogluco-amylopectin water dikinase activity	Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-amylopectin = n AMP + n hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin.	got7fsn_ti												EC:2.7.9.5|MetaCyc:RXN-12204		molecular_function											owl:Class	
GO:0051752	biolink:NamedThing	phosphoglucan, water dikinase activity	Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate.	got7fsn_ti	ATP:phospho-alpha-glucan, water phosphotransferase activity|OK1|PWD											EC:2.7.9.5|MetaCyc:2.7.9.5-RXN		molecular_function											owl:Class	
GO:0140592	biolink:NamedThing	histone methyltransferase activity (H3-R8 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 8) = S-adenosyl-L-homocysteine + (histone H3-N-methyl-arginine (position 8). This reaction is the addition of a methyl group to arginine at position 8 of histone H3.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20037					pg	2021-02-09T14:13:17Z						molecular_function											owl:Class	
GO:1902555	biolink:NamedThing	endoribonuclease complex	A protein complex which is capable of endoribonuclease activity.	got7fsn_ti	Ire1 complex dimer|Ire1 complex homodimer|Ire1 complex homooligomer				An example is IRE1 in S. cerevisiae (UniProt ID P32361) in PMID:18191223 (inferred from direct assay).		bhm	2013-12-06T16:09:31Z						cellular_component											owl:Class	
GO:0046404	biolink:NamedThing	polydeoxyribonucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.	got7fsn_ti	ATP-dependent DNA kinase activity|ATP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity|ATP-dependent DNA 5'-hydroxyl-kinase activity	https://github.com/geneontology/go-ontology/issues/21619										KEGG_REACTION:R03840|MetaCyc:POLYNUCLEOTIDE-5-HYDROXYL-KINASE-RXN|EC:2.7.1.78|RHEA:15669		molecular_function											owl:Class	
GO:0008661	biolink:NamedThing	1-deoxy-D-xylulose-5-phosphate synthase activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2).	got7fsn_ti	pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)|DXP-synthase activity|DOXP synthase activity|1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity|1-deoxyxylulose-5-phosphate synthase activity											RHEA:12605|MetaCyc:DXS-RXN|KEGG_REACTION:R05636|EC:2.2.1.7		molecular_function											owl:Class	
GO:0047443	biolink:NamedThing	4-hydroxy-4-methyl-2-oxoglutarate aldolase activity	Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.	got7fsn_ti	gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase activity|4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming)|pyruvate aldolase activity|4-hydroxy-4-methyl-2-ketoglutarate aldolase activity|4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase activity											EC:4.1.3.17|MetaCyc:4.1.3.17-RXN|RHEA:22748		molecular_function											owl:Class	
GO:0010739	biolink:NamedThing	positive regulation of protein kinase A signaling	Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	positive regulation of protein kinase A signalling cascade|positive regulation of protein kinase A signaling cascade|positive regulation of PKA signaling cascade													biological_process											owl:Class	
GO:0051896	biolink:NamedThing	regulation of protein kinase B signaling	Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.	got7fsn_ti	regulation of protein kinase B signalling cascade|regulation of PKB signalling cascade|regulation of PKB signaling cascade|regulation of AKT signalling cascade|regulation of protein kinase B signaling cascade|regulation of AKT signaling cascade													biological_process											owl:Class	
GO:0103098	biolink:NamedThing	CYP79F1 tetrahomomethionine monooxygenase activity	Catalysis of the reaction: 2 H+ + tetrahomomethionine + 2 O2 + 2 NADPH <=> 3 H2O + carbon dioxide + 2 NADP + 7-methylthioheptanaldoxime.	got7fsn_ti												MetaCyc:RXNQT-4311		molecular_function											owl:Class	
GO:0034890	biolink:NamedThing	endosulfan diol hydrolyase (cyclizing) activity	Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O.	got7fsn_ti												UM-BBD_reactionID:r1386		molecular_function											owl:Class	
GO:0043463	biolink:NamedThing	regulation of rhamnose catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.	got7fsn_ti	regulation of rhamnose breakdown|regulation of rhamnose catabolism|regulation of rhamnose degradation													biological_process											owl:Class	
GO:0033965	biolink:NamedThing	aculeacin-A deacylase activity	Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain.	got7fsn_ti	aculeacin A acylase activity|aculeacin-A amidohydrolase activity											MetaCyc:3.5.1.70-RXN|EC:3.5.1.70		molecular_function											owl:Class	
GO:0006719	biolink:NamedThing	juvenile hormone catabolic process	The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	got7fsn_ti	juvenile hormone catabolism|juvenile hormone breakdown|juvenile hormone degradation													biological_process											owl:Class	
GO:0044346	biolink:NamedThing	fibroblast apoptotic process	Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti	fibroblast apoptosis						jl	2010-09-23T11:33:38Z						biological_process											owl:Class	
GO:0071037	biolink:NamedThing	nuclear polyadenylation-dependent snRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.	got7fsn_ti	nuclear poly(A)-dependent snRNA catabolic process						krc	2009-07-29T01:07:18Z						biological_process											owl:Class	
GO:0016076	biolink:NamedThing	snRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.	got7fsn_ti	snRNA catabolism|snRNA degradation|snRNA breakdown													biological_process											owl:Class	
GO:0032945	biolink:NamedThing	negative regulation of mononuclear cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.	got7fsn_ti	negative regulation of PBMC proliferation|negative regulation of peripheral blood mononuclear cell proliferation													biological_process											owl:Class	
GO:0031254	biolink:NamedThing	cell trailing edge	The area of a motile cell opposite to the direction of movement.	got7fsn_ti	trailing edge|back of cell													cellular_component											owl:Class	
GO:0051043	biolink:NamedThing	regulation of membrane protein ectodomain proteolysis	Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).	got7fsn_ti														biological_process											owl:Class	
GO:0071163	biolink:NamedThing	DNA replication preinitiation complex assembly	The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins immediately prior to the initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity.	got7fsn_ti	pre-IC complex assembly|DNA replication preinitiation complex formation						mah	2009-11-19T11:13:41Z			GO:1902293|GO:1902316			biological_process											owl:Class	
GO:0071096	biolink:NamedThing	alphaV-beta3 integrin-gelsolin complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin.	got7fsn_ti	ITGAV-ITGB3-Gsn complex						mah	2009-11-06T04:49:31Z						cellular_component											owl:Class	
GO:0030046	biolink:NamedThing	parallel actin filament bundle assembly	Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.	got7fsn_ti														biological_process											owl:Class	
GO:0102988	biolink:NamedThing	9,12-cis-hexadecadienoic acid delta 15 desaturase activity	Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor <=> 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-9617|RHEA:46232		molecular_function											owl:Class	
GO:0052687	biolink:NamedThing	(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.	got7fsn_ti	3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity											KEGG_REACTION:R06396		molecular_function											owl:Class	
GO:0047311	biolink:NamedThing	1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity	Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine.	got7fsn_ti	1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol aminotransferase activity|1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase activity|L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase activity|guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase activity											EC:2.6.1.56|KEGG_REACTION:R03502|MetaCyc:2.6.1.56-RXN|RHEA:15497		molecular_function											owl:Class	
GO:0000049	biolink:NamedThing	tRNA binding	Binding to a transfer RNA.	got7fsn_ti	base pairing with tRNA										GO:0000946			molecular_function											owl:Class	
GO:0034365	biolink:NamedThing	discoidal high-density lipoprotein particle	A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).	got7fsn_ti	discoidal HDL|nascent high-density lipoprotein particle|nascent HDL													cellular_component											owl:Class	
GO:0034823	biolink:NamedThing	citronellyl-CoA ligase activity	Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi.	got7fsn_ti												KEGG_REACTION:R08088|UM-BBD_reactionID:r1157		molecular_function											owl:Class	
GO:0019703	biolink:NamedThing	coenzyme A-peptidyl-cysteine covalent linking	The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide.	got7fsn_ti												RESID:AA0306		biological_process											owl:Class	
GO:0036157	biolink:NamedThing	outer dynein arm	Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.	got7fsn_ti	outer dynein arm complex						bf	2012-03-21T01:25:03Z						cellular_component											owl:Class	
GO:0047855	biolink:NamedThing	dihydrobunolol dehydrogenase activity	Catalysis of the reaction: dihydrobunolol + NADP(+) = bunolol + H(+) + NADPH.	got7fsn_ti	bunolol reductase activity|(+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase activity											RHEA:15925|MetaCyc:DIHYDROBUNOLOL-DEHYDROGENASE-RXN|EC:1.1.1.160|KEGG_REACTION:R04623		molecular_function											owl:Class	
GO:0072452	biolink:NamedThing	response to G2 transition size control checkpoint signaling	A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling.	got7fsn_ti	response to G2/M transition size control checkpoint signaling|response to mitotic cell cycle G2/M transition size control checkpoint signaling|response to signal involved in G2/M transition size control checkpoint|G2/M transition size control checkpoint effector process						mah	2010-12-09T11:14:12Z						biological_process											owl:Class	
GO:0047988	biolink:NamedThing	hydroxyacid-oxoacid transhydrogenase activity	Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.	got7fsn_ti	transhydrogenase, hydroxy acid-oxo acid|(S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase activity											Reactome:R-HSA-880033|Reactome:R-HSA-880002|EC:1.1.99.24|MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0004756	biolink:NamedThing	selenide, water dikinase activity	Catalysis of the reaction: ATP + H(2)O + hydrogen selenide = AMP + 3 H(+) + phosphate + selenophosphorate.	got7fsn_ti	ATP:selenide, water phosphotransferase activity|selenium donor protein activity|selenophosphate synthase activity|selenide,water dikinase activity|selenophosphate synthetase activity											KEGG_REACTION:R03595|EC:2.7.9.3|RHEA:18737|MetaCyc:2.7.9.3-RXN|Reactome:R-HSA-8959510|UM-BBD_reactionID:r0833		molecular_function											owl:Class	
GO:0050699	biolink:NamedThing	WW domain binding	Binding to a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.	got7fsn_ti														molecular_function											owl:Class	
GO:0051879	biolink:NamedThing	Hsp90 protein binding	Binding to Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.	got7fsn_ti	Hsp90 binding|Hsp90 class protein binding													molecular_function											owl:Class	
GO:2000860	biolink:NamedThing	positive regulation of aldosterone secretion	Any process that activates or increases the frequency, rate or extent of aldosterone secretion.	got7fsn_ti							bf	2011-07-26T08:47:34Z						biological_process											owl:Class	
GO:0060035	biolink:NamedThing	notochord cell development	The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0005035	biolink:NamedThing	death receptor activity	Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.	got7fsn_ti	apoptosis-activating receptor activity													molecular_function											owl:Class	
GO:0002365	biolink:NamedThing	gamma-delta T cell lineage commitment	The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell.	got7fsn_ti	gamma-delta T lymphocyte lineage commitment|gamma-delta T-cell lineage commitment|gamma-delta T-lymphocyte lineage commitment													biological_process											owl:Class	
GO:0018674	biolink:NamedThing	(S)-limonene 3-monooxygenase activity	Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+).	got7fsn_ti	(-)-limonene 3-hydroxylase activity|(-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) activity|(-)-limonene 3-monooxygenase activity|limonene 3-hydroxylase activity|(S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating)											EC:1.14.14.99|MetaCyc:--LIMONENE-3-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0739|KEGG_REACTION:R02469|RHEA:15129		molecular_function											owl:Class	
GO:0016212	biolink:NamedThing	kynurenine-oxoglutarate transaminase activity	Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.	got7fsn_ti	kynurenine-oxoglutarate aminotransferase activity|L-kynurenine:2-oxoglutarate aminotransferase activity|kynurenine transaminase (cyclizing)|kynurenine 2-oxoglutarate transaminase activity|kynurenine--oxoglutarate aminotransferase activity|kynurenine aminotransferase activity|L-kynurenine aminotransferase activity											MetaCyc:2.6.1.7-RXN|RHEA:20964|Reactome:R-HSA-901097|Reactome:R-HSA-893583|Reactome:R-HSA-893596|EC:2.6.1.7		molecular_function											owl:Class	
GO:0071965	biolink:NamedThing	multicellular organismal locomotion	Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.	got7fsn_ti							mah	2010-10-14T10:34:35Z						biological_process											owl:Class	
GO:0038180	biolink:NamedThing	nerve growth factor signaling pathway	A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	NGF signaling pathway|nerve growth factor signalling pathway				Nerve growth factor (NGF) binds at least two classes of receptors: the p75 LNGFR (low-affinity nerve growth factor receptor) and TrkA, a transmembrane tyrosine kinase.		bf	2013-05-15T11:04:05Z				Wikipedia:Nerve_growth_factor		biological_process											owl:Class	
GO:0051431	biolink:NamedThing	corticotropin-releasing hormone receptor 2 binding	Binding to a corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery.	got7fsn_ti	type 2 corticotropin releasing factor receptor binding|CRHR2 binding|type 2 corticotropin releasing factor receptor ligand|type 2 corticotropin-releasing factor receptor binding										GO:0031744			molecular_function											owl:Class	
GO:1900032	biolink:NamedThing	regulation of trichome patterning	Any process that modulates the frequency, rate or extent of trichome patterning.	got7fsn_ti	regulation of trichome pattern formation|regulation of trichome spacing|regulation of trichome pattern specification|regulation of trichome pattern biosynthesis|regulation of trichome distribution						tb	2012-01-13T11:10:46Z						biological_process											owl:Class	
GO:0010423	biolink:NamedThing	negative regulation of brassinosteroid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.	got7fsn_ti														biological_process											owl:Class	
GO:0052642	biolink:NamedThing	lysophosphatidic acid phosphatase activity	Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol.	got7fsn_ti	lysophosphatidate phosphatase activity|LPA phosphatase activity											Reactome:R-HSA-8878654		molecular_function											owl:Class	
GO:0097010	biolink:NamedThing	eukaryotic translation initiation factor 4F complex assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.	got7fsn_ti	eIF-4F assembly|eIF4F assembly						pr	2011-03-21T04:19:26Z						biological_process											owl:Class	
GO:0102923	biolink:NamedThing	3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase activity	Catalysis of the reaction: 3'-N-debenzoyltaxol + benzoyl-CoA = H+ + paclitaxel + coenzyme A.	got7fsn_ti												MetaCyc:RXN-8859|RHEA:33687		molecular_function											owl:Class	
GO:0150103	biolink:NamedThing	reactive gliosis	A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells.	got7fsn_ti	gliosis						bc	2019-05-21T12:37:31Z						biological_process											owl:Class	
GO:0046524	biolink:NamedThing	sucrose-phosphate synthase activity	Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate.	got7fsn_ti	UDPglucose-fructose-phosphate glucosyltransferase activity|sucrose phosphate-uridine diphosphate glucosyltransferase activity|UDP-glucose-fructose-phosphate glucosyltransferase activity|SPS|UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity|sucrosephosphate-UDP glucosyltransferase activity|sucrose phosphate synthetase activity|uridine diphosphoglucose-fructose phosphate glucosyltransferase activity|UDPglucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity|sucrose 6-phosphate synthase activity											MetaCyc:SUCROSE-PHOSPHATE-SYNTHASE-RXN|RHEA:22172|EC:2.4.1.14		molecular_function											owl:Class	
GO:0070332	biolink:NamedThing	CD20-Lck-Lyn-Fyn complex	A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn.	got7fsn_ti														cellular_component											owl:Class	
GO:0004190	biolink:NamedThing	aspartic-type endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.	got7fsn_ti	aspartic endopeptidase activity|aspartyl protease activity|aspartic protease activity|aspartate protease activity|carboxyl protease activity											EC:3.4.23.43|MetaCyc:3.4.23.36-RXN|MetaCyc:3.4.23.25-RXN|MetaCyc:3.4.23.32-RXN|MetaCyc:3.4.23.34-RXN|MetaCyc:3.4.23.43-RXN|EC:3.4.23.25|Reactome:R-HSA-157640|Reactome:R-HSA-2065357|EC:3.4.23.34|EC:3.4.23.15|EC:3.4.23.20|EC:3.4.23.1|Reactome:R-HSA-9017817|Reactome:R-HSA-2022403|MetaCyc:3.4.23.4-RXN|MetaCyc:3.4.23.15-RXN|Reactome:R-HSA-9013361|EC:3.4.23.35|Reactome:R-HSA-373705|MetaCyc:3.4.23.20-RXN|Reactome:R-HSA-2022412|EC:3.4.23.-|MetaCyc:3.4.23.5-RXN|EC:3.4.23.5|EC:3.4.23.36|MetaCyc:3.4.23.35-RXN|Reactome:R-HSA-2220988|Reactome:R-HSA-157353|EC:3.4.23.4|EC:3.4.23.32|Reactome:R-HSA-9604294|MetaCyc:3.4.23.1-RXN		molecular_function											owl:Class	
GO:0047275	biolink:NamedThing	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity	Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.	got7fsn_ti	UDP-galactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity|UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity|paragloboside synthase activity|GalT-4|uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide galactosyltransferase activity											MetaCyc:2.4.1.86-RXN|EC:2.4.1.86|RHEA:16045		molecular_function											owl:Class	
GO:0008830	biolink:NamedThing	dTDP-4-dehydrorhamnose 3,5-epimerase activity	Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.	got7fsn_ti	thymidine diphospho-4-ketorhamnose 3,5-epimerase activity|dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase activity|dTDP-4-keto-6-deoxyglucose 3,5-epimerase activity|TDP-4-ketorhamnose 3,5-epimerase activity|TDP-4-keto-L-rhamnose-3,5-epimerase activity											RHEA:16969|MetaCyc:DTDPDEHYDRHAMEPIM-RXN|KEGG_REACTION:R06514|EC:5.1.3.13		molecular_function											owl:Class	
GO:0102098	biolink:NamedThing	D-galacturonate reductase activity	Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+.	got7fsn_ti												RHEA:26345|MetaCyc:RXN-11151|EC:1.1.1.365		molecular_function											owl:Class	
GO:0061807	biolink:NamedThing	positive regulation of DNA recombination at centromere	Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.	got7fsn_ti	positive regulation of centromeric recombination						dph	2016-11-10T15:20:04Z						biological_process											owl:Class	
GO:0052084	biolink:NamedThing	modulation by symbiont of host ethylene-mediated defense response	Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|modulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|modulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction										GO:0052279|GO:0052441|GO:0052077			biological_process											owl:Class	
GO:0008930	biolink:NamedThing	methylthioadenosine nucleosidase activity	Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose.	got7fsn_ti	MTA nucleosidase activity|MeSAdo nucleosidase activity|S-methyl-5'-thioadenosine adeninehyrolase activity|5'-methylthioadenosine nucleosidase activity|methylthioadenosine methylthioribohydrolase activity											EC:3.2.2.16|RHEA:13617|MetaCyc:METHYLTHIOADENOSINE-NUCLEOSIDASE-RXN		molecular_function											owl:Class	
GO:0120100	biolink:NamedThing	bacterial-type flagellum motor	A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation.	got7fsn_ti							krc	2017-10-03T15:44:35Z						cellular_component											owl:Class	
GO:0050566	biolink:NamedThing	asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP.	got7fsn_ti	Asp-tRNA(Asn) amidotransferase activity|Asp-tRNAAsn:L-glutamine amido-ligase (ADP-forming)|asparaginyl-tRNA synthase (glutamine-hydrolysing)|Asp-tRNAAsn amidotransferase activity|aspartyl-tRNAAsn amidotransferase activity|Asp-AdT activity|aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming)|aspartyl-tRNA(Asn) amidotransferase activity											EC:6.3.5.6|Wikipedia:Asparaginyl-tRNA_synthase_(glutamine-hydrolysing)|MetaCyc:6.3.5.6-RXN|RHEA:14513		molecular_function											owl:Class	
GO:0075029	biolink:NamedThing	formation of appressorium germ tube hook structure	The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation.	got7fsn_ti	formation of germ tube tip of symbiont on or near the exterior of host|formation of symbiont germ tube hook structure for appressorium development|symbiont germ tube hook structure formation on or near host|formation of symbiont germ tube hook structure on or near host													biological_process											owl:Class	
GO:0043701	biolink:NamedThing	cyanosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance.	got7fsn_ti														cellular_component											owl:Class	
GO:0047814	biolink:NamedThing	D-arabinokinase activity	Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.	got7fsn_ti	D-arabinokinase (phosphorylating)|ATP:D-arabinose 5-phosphotransferase activity											RHEA:24588|MetaCyc:D-ARABINOKINASE-RXN|EC:2.7.1.54|KEGG_REACTION:R01573		molecular_function											owl:Class	
GO:0035571	biolink:NamedThing	N-terminal peptidyl-serine monomethylation	The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine.	got7fsn_ti							bf	2010-08-06T01:58:56Z						biological_process											owl:Class	
GO:0052676	biolink:NamedThing	3-methylbutanol:NAD oxidoreductase activity	Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde.	got7fsn_ti	3-methylbutanal reductase (NAD) activity|3-methylbutyraldehyde reductase (NAD) activity|isoamyl alcohol oxidase (NAD) activity|3-methylbutanol:NAD+ oxidoreductase activity						ai	2011-04-12T11:22:42Z				KEGG_REACTION:R05685|RHEA:18529		molecular_function											owl:Class	
GO:0010184	biolink:NamedThing	cytokinin transport	The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0019096	biolink:NamedThing	pole plasm mitochondrial lrRNA localization	Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	got7fsn_ti	pole plasm mitochondrial lrRNA localisation|establishment and maintenance of mitochondrial lrRNA localization in pole plasm|oocyte pole plasm mitochondrial lrRNA localization										GO:0048118			biological_process											owl:Class	
GO:0019355	biolink:NamedThing	nicotinamide nucleotide biosynthetic process from aspartate	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including aspartate.	got7fsn_ti	nicotinamide nucleotide formation from aspartate|nicotinamide nucleotide synthesis from aspartate|nicotinamide nucleotide anabolism from aspartate													biological_process											owl:Class	
GO:0043695	biolink:NamedThing	detection of pheromone	The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0005592	biolink:NamedThing	collagen type XI trimer	A collagen heterotrimer containing type XI alpha chains in alpha1(XI)alpha2(XI)alpha3(XI) trimers; type XI collagen triple helices associate to form fibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0047438	biolink:NamedThing	2-dehydro-3-deoxy-L-pentonate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate.	got7fsn_ti	3-deoxy-D-pentulosonic acid aldolase|2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming)|2-keto-3-deoxy-D-xylonate aldolase activity|2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase activity|2-keto-3-deoxy-L-arabonate aldolase activity|2-keto-3-deoxy-L-pentonate aldolase activity											RHEA:18545|MetaCyc:4.1.2.18-RXN|EC:4.1.2.18		molecular_function											owl:Class	
GO:0015324	biolink:NamedThing	peptide-acetyl-CoA secondary active transmembrane transporter activity	Enables the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	peptide-acetyl-CoA transporter activity													molecular_function											owl:Class	
GO:0022000	biolink:NamedThing	forebrain induction by the anterior neural ridge	The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate.	got7fsn_ti														biological_process											owl:Class	
GO:0042464	biolink:NamedThing	dosage compensation by hypoactivation of X chromosome	Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans.	got7fsn_ti														biological_process											owl:Class	
GO:0085020	biolink:NamedThing	protein K6-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair.	got7fsn_ti	protein K6-linked polyubiquitination						jl	2010-06-01T03:05:03Z						biological_process											owl:Class	
GO:0106099	biolink:NamedThing	2-keto-3-deoxy-L-rhamnonate aldolase activity	Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde.	got7fsn_ti							hjd	2018-02-15T16:12:17Z				RHEA:25784|EC:4.1.2.53		molecular_function											owl:Class	
GO:0033849	biolink:NamedThing	chrysanthemyl diphosphate synthase activity	Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.	got7fsn_ti	dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming) activity|CPPase activity											KEGG_REACTION:R08948|RHEA:14009|MetaCyc:2.5.1.67-RXN|EC:2.5.1.67		molecular_function											owl:Class	
GO:0102652	biolink:NamedThing	gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A9 + 2-oxoglutarate + O2 <=> gibberellin A51 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-171		molecular_function											owl:Class	
GO:0044601	biolink:NamedThing	protein denucleotidylation	The removal of a nucleotide from a protein amino acid.	got7fsn_ti							jl	2012-05-01T04:13:54Z						biological_process											owl:Class	
GO:0102039	biolink:NamedThing	alkylhydroperoxide reductase activity	Catalysis of the reaction: H2O + NAD + an alcohol <=> NADH + H+ + an organic hydroperoxide.	got7fsn_ti												EC:1.11.1.26|MetaCyc:R4-RXN		molecular_function											owl:Class	
GO:0060929	biolink:NamedThing	atrioventricular node cell fate commitment	The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.	got7fsn_ti	AV node cell fate commitment						dph	2009-09-29T12:01:24Z						biological_process											owl:Class	
GO:0008523	biolink:NamedThing	sodium-dependent multivitamin transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate.	got7fsn_ti												Reactome:R-HSA-429581|Reactome:R-HSA-199206|Reactome:R-HSA-199219		molecular_function											owl:Class	
GO:0007191	biolink:NamedThing	adenylate cyclase-activating dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	got7fsn_ti	dopamine receptor, adenylyl cyclase activating pathway|activation of adenylate cyclase activity by dopamine receptor signalling pathway|activation of adenylate cyclase activity by dopamine receptor signaling pathway|dopamine receptor, adenylate cyclase activating pathway													biological_process											owl:Class	
GO:0022818	biolink:NamedThing	sodium ion uniporter activity	Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.	got7fsn_ti														molecular_function											owl:Class	
GO:0062201	biolink:NamedThing	actin wave	A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis.	got7fsn_ti							dph	2020-01-02T13:45:03Z						cellular_component											owl:Class	
GO:0036383	biolink:NamedThing	3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity	Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O.	got7fsn_ti							bf	2013-05-23T11:31:09Z				MetaCyc:1.14.14.12-RXN|EC:1.14.14.12|KEGG_REACTION:R09819|RHEA:31731		molecular_function											owl:Class	
GO:0004968	biolink:NamedThing	gonadotropin-releasing hormone receptor activity	Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.	got7fsn_ti	GnRH receptor activity|gonadotrophin-releasing hormone receptor activity													molecular_function											owl:Class	
GO:0097219	biolink:NamedThing	compound sieve plate	A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement.	got7fsn_ti					Often located on an end wall of a sieve tube member. Unspecialized sieve areas may occur on other parts of the cell.		pr	2012-01-13T05:45:23Z						cellular_component											owl:Class	
GO:0034709	biolink:NamedThing	methylosome	A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains.	got7fsn_ti	20S methyltransferase complex|20S methylosome													cellular_component											owl:Class	
GO:0004963	biolink:NamedThing	follicle-stimulating hormone receptor activity	Combining with follicle-stimulating hormone to initiate a change in cell activity.	got7fsn_ti	FSH receptor activity|follicle stimulating hormone receptor activity													molecular_function											owl:Class	
GO:0072043	biolink:NamedThing	regulation of pre-tubular aggregate formation by cell-cell signaling	Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.	got7fsn_ti	regulation of pre-tubular aggregate formation by cell-cell signalling						mah	2010-01-25T03:12:03Z						biological_process											owl:Class	
GO:0035191	biolink:NamedThing	nuclear axial expansion	The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex.	got7fsn_ti	nuclear distribution along anterior-posterior axis|nucleus distribution along anterior-posterior axis													biological_process											owl:Class	
GO:0051481	biolink:NamedThing	negative regulation of cytosolic calcium ion concentration	Any process that decreases the concentration of calcium ions in the cytosol.	got7fsn_ti	reduction of calcium ion concentration in cytosol|cytoplasmic calcium ion concentration reduction|cytosolic calcium ion concentration reduction|reduction of calcium ion concentration in cytoplasm|reduction of cytosolic calcium ion concentration|reduction of cytoplasmic calcium ion concentration													biological_process											owl:Class	
GO:0000907	biolink:NamedThing	sulfonate dioxygenase activity	Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2.	got7fsn_ti	sulphonate dioxygenase activity|sulfonate/alpha-ketoglutarate dioxygenase activity													molecular_function											owl:Class	
GO:0039648	biolink:NamedThing	modulation by virus of host protein ubiquitination	Any process in which a virus modulates the frequency, rate or extent of protein ubiquitination in the host organism. Ubiquitination is the process in which one or more ubiquitin groups are added to a protein.	got7fsn_ti	modulation of host ubiquitin pathway by virus						bf	2012-10-09T15:20:47Z						biological_process											owl:Class	
GO:0007629	biolink:NamedThing	flight behavior	The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.	got7fsn_ti	flight behaviour													biological_process											owl:Class	
GO:0014827	biolink:NamedThing	intestine smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0000822	biolink:NamedThing	inositol hexakisphosphate binding	Binding to inositol hexakisphosphate.	got7fsn_ti	IP6 binding|InsP6 binding													molecular_function											owl:Class	
GO:0015928	biolink:NamedThing	fucosidase activity	Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative.	got7fsn_ti														molecular_function											owl:Class	
GO:0031910	biolink:NamedThing	cytostome	Stable, specialized structure for the ingestion of food by the cell into phagosomes.	got7fsn_ti												Wikipedia:Cytostome		cellular_component											owl:Class	
GO:0033799	biolink:NamedThing	myricetin 3'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.	got7fsn_ti	S-adenosyl-L-methionine:myricetin O-methyltransferase activity|myricetin 3-O-methyltransferase activity|CrCOMT2|flavonoid 3',5'-O-dimethyltransferase activity				Note that this term represents one of two reactions that are grouped together in EC:2.1.1.267						GO:0102437	EC:2.1.1.267;|MetaCyc:RXN-8451|KEGG_REACTION:R06815|MetaCyc:RXN-13912|RHEA:25629		molecular_function											owl:Class	
GO:0004017	biolink:NamedThing	adenylate kinase activity	Catalysis of the reaction: ATP + AMP = 2 ADP.	got7fsn_ti	myokinase activity|adenylokinase activity|adenylic kinase activity|ATP:AMP phosphotransferase activity|5'-AMP-kinase activity											Reactome:R-HSA-110145|Reactome:R-HSA-110141|EC:2.7.4.3|RHEA:12973|Reactome:R-HSA-74220|MetaCyc:ADENYL-KIN-RXN|Reactome:R-HSA-110144		molecular_function											owl:Class	
GO:1990743	biolink:NamedThing	protein sialylation	A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein.	got7fsn_ti							sl	2015-05-14T20:18:28Z						biological_process											owl:Class	
GO:0021773	biolink:NamedThing	striatal medium spiny neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum.	got7fsn_ti	striatal MSN differentiation|medium-sized spiny neuron differentiation													biological_process											owl:Class	
GO:0035874	biolink:NamedThing	cellular response to copper ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.	got7fsn_ti	cellular response to copper starvation						bf	2011-05-31T09:28:47Z						biological_process											owl:Class	
GO:0039619	biolink:NamedThing	T=4 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres.	got7fsn_ti							bf	2012-07-18T02:15:14Z				VZ:808		cellular_component											owl:Class	
GO:1990223	biolink:NamedThing	positive regulation by symbiont of cytokinin levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-16T15:27:27Z						biological_process											owl:Class	
GO:0071725	biolink:NamedThing	response to triacyl bacterial lipopeptide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.	got7fsn_ti	response to triacylated bacterial lipoprotein				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:16:40Z						biological_process											owl:Class	
GO:0072183	biolink:NamedThing	negative regulation of nephron tubule epithelial cell differentiation	Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.	got7fsn_ti							mah	2010-02-26T02:47:25Z						biological_process											owl:Class	
GO:0048095	biolink:NamedThing	female pigmentation	Establishment of a pattern of pigment in females.	got7fsn_ti														biological_process											owl:Class	
GO:0072633	biolink:NamedThing	interleukin-30 production	The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-30 complex production|interleukin-30 secretion|IL-30 production										GO:0072634			biological_process											owl:Class	
GO:0036295	biolink:NamedThing	cellular response to increased oxygen levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.	got7fsn_ti	cellular response to raised oxygen levels				This term should be used when an increase in oxygen levels is not considered a stress response. For a hyperoxic stress response, consider instead 'cellular response to hyperoxia ; GO:0071455'.		bf	2012-07-20T01:09:39Z						biological_process											owl:Class	
GO:0031826	biolink:NamedThing	type 2A serotonin receptor binding	Binding to a type 2A serotonin receptor.	got7fsn_ti	type 2A serotonin receptor ligand|5-hydroxytryptamine 2A receptor binding													molecular_function											owl:Class	
GO:0008457	biolink:NamedThing	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide.	got7fsn_ti	UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity|poly-N-acetyllactosamine extension enzyme activity|uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase											RHEA:23004|MetaCyc:2.4.1.163-RXN|EC:2.4.1.149		molecular_function											owl:Class	
GO:0052637	biolink:NamedThing	delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol.	got7fsn_ti														molecular_function											owl:Class	
GO:0042323	biolink:NamedThing	negative regulation of circadian sleep/wake cycle, non-REM sleep	Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.	got7fsn_ti	down regulation of circadian sleep/wake cycle, non-REM sleep|inhibition of circadian sleep/wake cycle, non-REM sleep|negative regulation of non-REM sleep|downregulation of circadian sleep/wake cycle, non-REM sleep|down-regulation of circadian sleep/wake cycle, non-REM sleep													biological_process											owl:Class	
GO:0045188	biolink:NamedThing	regulation of circadian sleep/wake cycle, non-REM sleep	Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.	got7fsn_ti	regulation of non-REM sleep													biological_process											owl:Class	
GO:0034389	biolink:NamedThing	lipid droplet organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.	got7fsn_ti	lipid particle organization|lipid body organization|lipid particle organisation|adiposome organization|lipid particle organization and biogenesis	https://github.com/geneontology/go-ontology/issues/15963|https://github.com/geneontology/go-ontology/issues/13534												biological_process											owl:Class	
GO:0010161	biolink:NamedThing	red light signaling pathway	The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	got7fsn_ti	red light signalling pathway|red light phototransduction|red light signal transduction													biological_process											owl:Class	
GO:0070701	biolink:NamedThing	mucus layer	An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes.	got7fsn_ti	mucous|mucus|extracellular proteinaceous gel|mucous layer						mah	2009-06-08T02:31:34Z						cellular_component											owl:Class	
GO:0030305	biolink:NamedThing	heparanase activity	Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains.	got7fsn_ti	heparinase activity											Reactome:R-HSA-1667005|Reactome:R-HSA-1678694		molecular_function											owl:Class	
GO:0048322	biolink:NamedThing	axial mesodermal cell fate commitment	The process in which a cell becomes committed to become an axial mesoderm cell.	got7fsn_ti	axial mesoderm cell fate commitment													biological_process											owl:Class	
GO:0051522	biolink:NamedThing	activation of monopolar cell growth	Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0051515	biolink:NamedThing	positive regulation of monopolar cell growth	Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.	got7fsn_ti	upregulation of monopolar cell growth|up regulation of monopolar cell growth|up-regulation of monopolar cell growth|stimulation of monopolar cell growth													biological_process											owl:Class	
GO:0060470	biolink:NamedThing	positive regulation of cytosolic calcium ion concentration involved in egg activation	The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.	got7fsn_ti	elevation of cytosolic calcium ion concentration involved in egg activation													biological_process											owl:Class	
GO:0021996	biolink:NamedThing	lamina terminalis formation	The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.	got7fsn_ti														biological_process											owl:Class	
GO:0050688	biolink:NamedThing	regulation of defense response to virus	Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.	got7fsn_ti	regulation of antiviral response													biological_process											owl:Class	
GO:0046695	biolink:NamedThing	SLIK (SAGA-like) complex	A SAGA-type histone acetyltransferase complex that contains a smaller form of Spt7 (lacking the SPT8 binding region) than the fungal SAGA complex, and consequently lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction.	got7fsn_ti	SAGA (alt) complex|SLIK/SALSA complex|SALSA complex				See also the cellular component term 'SAGA complex ; GO:0000124'.									cellular_component											owl:Class	
GO:0047035	biolink:NamedThing	testosterone dehydrogenase (NAD+) activity	Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.	got7fsn_ti	3alpha,17beta-hydroxy steroid dehydrogenase activity|17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity|17-ketoreductase activity|17beta-HSD|17-beta-HSD activity|3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)|3alpha(17beta)-HSD|testosterone 17beta-dehydrogenase activity|3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity|testosterone 17-beta-dehydrogenase (NAD+) activity|testosterone 17b-dehydrogenase activity|3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity										GO:0050327	KEGG_REACTION:R01836|MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN|MetaCyc:1.1.1.239-RXN|EC:1.1.1.239|RHEA:14929|Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)		molecular_function											owl:Class	
GO:0006452	biolink:NamedThing	translational frameshifting	A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon.	got7fsn_ti												Wikipedia:Translational_frameshift		biological_process											owl:Class	
GO:0048402	biolink:NamedThing	intermediate mesoderm structural organization	The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	intermediate mesoderm structural organisation													biological_process											owl:Class	
GO:2000942	biolink:NamedThing	regulation of amylopectin metabolic process	Any process that modulates the frequency, rate or extent of amylopectin metabolic process.	got7fsn_ti	regulation of Amylopectin metabolism						tt	2011-08-01T02:10:28Z						biological_process											owl:Class	
GO:0018164	biolink:NamedThing	protein-DNA covalent cross-linking via peptidyl-threonine	The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine.	got7fsn_ti	DNA-protein covalent cross-linking via peptidyl-threonine											RESID:AA0255		biological_process											owl:Class	
GO:0032639	biolink:NamedThing	TRAIL production	The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	TRAIL biosynthetic process				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0045553			biological_process											owl:Class	
GO:0060370	biolink:NamedThing	susceptibility to T cell mediated cytotoxicity	The process of causing a cell to become susceptible to T cell mediated cytotoxicity.	got7fsn_ti														biological_process											owl:Class	
GO:0001916	biolink:NamedThing	positive regulation of T cell mediated cytotoxicity	Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.	got7fsn_ti	upregulation of T cell mediated cytotoxicity|stimulation of T cell mediated cytotoxicity|positive regulation of T cell mediated cytolysis|activation of T cell mediated cytotoxicity|positive regulation of T-lymphocyte mediated cytotoxicity|positive regulation of T cell mediated apoptosis|up-regulation of T cell mediated cytotoxicity|up regulation of T cell mediated cytotoxicity|positive regulation of T-cell mediated apoptosis|positive regulation of T cell mediated cell death|positive regulation of T-cell mediated cell death|positive regulation of T-cell mediated cell killing|positive regulation of T-cell mediated cytotoxicity|positive regulation of T cell mediated cell killing|positive regulation of T-cell mediated cytolysis|positive regulation of T lymphocyte mediated cytotoxicity													biological_process											owl:Class	
GO:0140398	biolink:NamedThing	versicolorin B desaturase activity	Catalyzes the reaction: versicolorin B + NADPH + O(2) <=> versicolorin A + NADP(+) + 2 H(2)O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.	got7fsn_ti							pg	2019-11-29T10:30:25Z				RHEA:35743|MetaCyc:RXN-9495|KEGG_REACTION:R10479		molecular_function											owl:Class	
GO:0072373	biolink:NamedThing	alpha-carotene epsilon hydroxylase activity	Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O.	got7fsn_ti							mah	2010-11-19T03:52:25Z						molecular_function											owl:Class	
GO:0018470	biolink:NamedThing	4-hydroxybutaraldehyde dehydrogenase activity	Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.	got7fsn_ti												UM-BBD_reactionID:r0014		molecular_function											owl:Class	
GO:0006035	biolink:NamedThing	cuticle chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.	got7fsn_ti	cuticle chitin synthesis|cuticle chitin anabolism|cuticle chitin biosynthesis|cuticle chitin formation													biological_process											owl:Class	
GO:0031386	biolink:NamedThing	protein tag	A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.	got7fsn_ti	ubiquitin-like protein modifier|covalent modifier|ubiquitin|protein tagging activity				Use this term to annotate conjugated tags, not for conjugating enzymes. At the time of writing, all known gene products with this activity are ubiquitin-like, either based on overall sequence similarity or the presence of common motifs and structures.									molecular_function											owl:Class	
GO:0008936	biolink:NamedThing	nicotinamidase activity	Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.	got7fsn_ti	nicotine deamidase activity|NAMase activity|nicotinamide amidase activity|nicotinamide amidohydrolase activity|YNDase activity|nicotinamide deaminase activity											MetaCyc:NICOTINAMID-RXN|EC:3.5.1.19|RHEA:14545		molecular_function											owl:Class	
GO:0019916	biolink:NamedThing	peptidyl-D-alanine racemization, direct	The racemization of peptidyl-alanine.	got7fsn_ti												RESID:AA0191		biological_process											owl:Class	
GO:0055022	biolink:NamedThing	negative regulation of cardiac muscle tissue growth	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.	got7fsn_ti	negative regulation of heart muscle growth|down-regulation of cardiac muscle growth|inhibition of cardiac muscle growth|downregulation of cardiac muscle growth|down regulation of cardiac muscle growth													biological_process											owl:Class	
GO:0098769	biolink:NamedThing	TIMP family protein binding	Binding to a member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family.	got7fsn_ti														molecular_function											owl:Class	
GO:0007288	biolink:NamedThing	sperm axoneme assembly	The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.	got7fsn_ti														biological_process											owl:Class	
GO:0048249	biolink:NamedThing	high-affinity phosphate transmembrane transporter activity	Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity phosphate transmembrane transporter activity													molecular_function											owl:Class	
GO:0015114	biolink:NamedThing	phosphate ion transmembrane transporter activity	Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.	got7fsn_ti	phosphate transmembrane transporter activity						pr	2012-11-22T15:43:10Z			GO:1901677	RHEA:32823		molecular_function											owl:Class	
GO:0035236	biolink:NamedThing	proctolin receptor activity	Combining with the neuropeptide proctolin, to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:1990092	biolink:NamedThing	calcium-dependent self proteolysis	The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.	got7fsn_ti							sl	2013-05-06T17:33:34Z						biological_process											owl:Class	
GO:0097264	biolink:NamedThing	self proteolysis	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.	got7fsn_ti	self-proteolysis|autolysis						pr	2012-03-09T12:43:24Z						biological_process											owl:Class	
GO:1902422	biolink:NamedThing	hydrogen biosynthetic process	The chemical reactions and pathways resulting in the formation of H2 (dihydrogen).	got7fsn_ti	dihydrogen synthesis|molecular hydrogen biosynthesis|H2 biosynthesis|hydrogen production|hydrogen synthesis|hydrogen anabolism|hydrogen biosynthesis|hydrogen generation|hydrogen formation						jl	2013-09-18T14:34:32Z						biological_process											owl:Class	
GO:0035287	biolink:NamedThing	head segmentation	Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial).	got7fsn_ti					See also the fly_anatomy.ontology term 'head segment ; FBbt:00000006' and its children.									biological_process											owl:Class	
GO:0035574	biolink:NamedThing	histone H4-K20 demethylation	The modification of histone H4 by the removal of a methyl group from lysine at position 20 of the histone.	got7fsn_ti							bf	2010-08-13T10:50:06Z						biological_process											owl:Class	
GO:0061307	biolink:NamedThing	cardiac neural crest cell differentiation involved in heart development	The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.	got7fsn_ti							dph	2010-09-23T08:50:56Z						biological_process											owl:Class	
GO:0047706	biolink:NamedThing	biochanin-A reductase activity	Catalysis of the reaction: dihydrobiochanin A + NADP(+) = biochanin A + H(+) + NADPH.	got7fsn_ti	dihydrobiochanin-A:NADP+ delta2-oxidoreductase activity											MetaCyc:BIOCHANIN-A-REDUCTASE-RXN|RHEA:12817|KEGG_REACTION:R02954|EC:1.3.1.46		molecular_function											owl:Class	
GO:0061386	biolink:NamedThing	closure of optic fissure	The closure of the temporary ventral gap in the optic cup that contributes to its shaping.	got7fsn_ti	closure or choriod fissure						dph	2011-03-30T08:14:59Z						biological_process											owl:Class	
GO:0006426	biolink:NamedThing	glycyl-tRNA aminoacylation	The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:1990536	biolink:NamedThing	phosphoenolpyruvate transmembrane import into Golgi lumen	The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane.	got7fsn_ti							vw	2014-11-14T10:17:01Z						biological_process											owl:Class	
GO:0015714	biolink:NamedThing	phosphoenolpyruvate transport	The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0052837	biolink:NamedThing	thiazole biosynthetic process	The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.	got7fsn_ti	thiazole synthesis|thiazole anabolism|thiazole formation|thiazole biosynthesis						ai	2011-11-29T03:33:05Z						biological_process											owl:Class	
GO:0030160	biolink:NamedThing	synaptic receptor adaptor activity	The binding activity of a molecule that provides a physical support bridging a synaptic signaling receptor and a downstream signaling molecule.	got7fsn_ti	GKAP/Homer scaffold protein|postsynaptic density scaffold protein|GKAP/Homer scaffold activity	https://github.com/geneontology/go-ontology/issues/18409												molecular_function											owl:Class	
GO:0061680	biolink:NamedThing	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde.	got7fsn_ti							dph	2015-01-22T08:51:31Z				MetaCyc:ENTNER-DOUDOROFF-PWY-II		biological_process											owl:Class	
GO:0098596	biolink:NamedThing	imitative learning	Learning in which new behaviors are acquired through imitation.	got7fsn_ti							dos	2014-04-10T11:00:39Z				Wikipedia:Observational_learning#Observational_learning_compared_to_imitation|Wikipedia:Imitative_learning		biological_process											owl:Class	
GO:0047249	biolink:NamedThing	sarsapogenin 3-beta-glucosyltransferase activity	Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H(+) + UDP.	got7fsn_ti	sarsapogenin 3beta-glucosyltransferase activity|uridine diphosphoglucose-sarsapogenin glucosyltransferase activity|UDPglucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity|UDP-glucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity											RHEA:14461|KEGG_REACTION:R04359|EC:2.4.1.193|MetaCyc:2.4.1.193-RXN		molecular_function											owl:Class	
GO:0102159	biolink:NamedThing	baicalein 7-O-glucuronosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein <=> H+ + UDP + baicalin.	got7fsn_ti												MetaCyc:RXN-11755|EC:2.4.1.253|RHEA:28314		molecular_function											owl:Class	
GO:0098691	biolink:NamedThing	dopaminergic synapse	A synapse that uses dopamine as a neurotransmitter.	got7fsn_ti							dos	2017-03-07T14:51:52Z						cellular_component											owl:Class	
GO:0061569	biolink:NamedThing	UDP phosphorylation	The process of introducing a phosphate group into UDP, uridine diphosphate, to produce UTP.	got7fsn_ti							dph	2013-08-01T12:59:32Z						biological_process											owl:Class	
GO:0004460	biolink:NamedThing	L-lactate dehydrogenase (cytochrome) activity	Catalysis of the reaction: (S)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate.	got7fsn_ti	lactic cytochrome c reductase activity|lactic acid dehydrogenase activity|(S)-lactate:ferricytochrome-c 2-oxidoreductase activity|dehydrogenase, lactate (cytochrome)|cytochrome b2|L(+)-lactate:cytochrome c oxidoreductase activity|L-lactate ferricytochrome c oxidoreductase activity|lactate dehydrogenase (cytochrome)|cytochrome b2 (flavin-free derivative of flavocytochrome b2)|flavocytochrome b2|L-lactate cytochrome c reductase activity|L-lactate cytochrome c oxidoreductase activity											EC:1.1.2.3|MetaCyc:L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN|RHEA:19909		molecular_function											owl:Class	
GO:0038183	biolink:NamedThing	bile acid signaling pathway	A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti							bf	2013-05-16T10:35:10Z						biological_process											owl:Class	
GO:0061539	biolink:NamedThing	octopamine secretion	The controlled release of octopamine by a cell.	got7fsn_ti							dph	2013-06-21T16:24:02Z						biological_process											owl:Class	
GO:0036001	biolink:NamedThing	'de novo' pyridoxal 5'-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components.	got7fsn_ti	'de novo' pyridoxal 5'-phosphate formation|'de novo' pyridoxal 5'-phosphate biosynthesis|'de novo' pyridoxal 5'-phosphate anabolism|'de novo' PLP biosynthesis|'de novo' pyridoxal phosphate biosynthetic process|'de novo' pyridoxal 5'-phosphate synthesis						bf	2011-09-06T02:04:53Z				MetaCyc:PYRIDOXSYN-PWY		biological_process											owl:Class	
GO:0042823	biolink:NamedThing	pyridoxal phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.	got7fsn_ti	pyridoxal phosphate synthesis|pyridoxal phosphate anabolism|pyridoxal phosphate formation|pyridoxal phosphate biosynthesis|active vitamin B6 biosynthesis|active vitamin B6 biosynthetic process											MetaCyc:PWY0-845		biological_process											owl:Class	
GO:0042864	biolink:NamedThing	pyochelin biosynthetic process	The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).	got7fsn_ti	pyochelin biosynthetic process, peptide formation|pyochelin formation|pyochelin synthesis|pyochelin biosynthetic process, peptide modification|pyochelin anabolism|pyochelin biosynthesis										GO:0031187|GO:0031188			biological_process											owl:Class	
GO:0004715	biolink:NamedThing	non-membrane spanning protein tyrosine kinase activity	Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.	got7fsn_ti	cytoplasmic protein tyrosine kinase activity|focal adhesion kinase activity|janus kinase 3 activity|ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|p60c-src protein tyrosine kinase activity|janus kinase 2 activity|janus kinase 1 activity|ATP:protein-tyrosine O-phosphotransferase activity|Bruton's tyrosine kinase activity|non-specific protein-tyrosine kinase activity											Reactome:R-HSA-6786095|EC:2.7.10.2|Reactome:R-HSA-1112703|MetaCyc:2.7.10.2-RXN|Reactome:R-HSA-6786096|Reactome:R-HSA-6788582|Reactome:R-HSA-1168459|Reactome:R-HSA-879910|Reactome:R-HSA-8871373|Reactome:R-HSA-1369115|Reactome:R-HSA-437936|Reactome:R-HSA-432148|Reactome:R-HSA-1112602|Reactome:R-HSA-453200|Reactome:R-HSA-1295519|Reactome:R-HSA-1168767|Reactome:R-HSA-1168423		molecular_function											owl:Class	
GO:0030600	biolink:NamedThing	feruloyl esterase activity	Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide.	got7fsn_ti	4-hydroxy-3-methoxycinnamoyl-sugar hydrolase activity|FAE-III|hydroxycinnamoyl esterase activity|FAE-II|ferulic acid esterase activity|FAE-I|hemicellulase accessory|FAEA|cinnAE|cinnamoyl ester hydrolase activity											MetaCyc:3.1.1.73-RXN|EC:3.1.1.73		molecular_function											owl:Class	
GO:0051909	biolink:NamedThing	acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate	Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O.	got7fsn_ti	3-hydroxypropenoate dehydratase activity|alkynoate hydratase activity|acetylenemonocarboxylate hydratase activity|acetylenecarboxylate hydratase activity											EC:4.2.1.27		molecular_function											owl:Class	
GO:1990048	biolink:NamedThing	anterograde neuronal dense core vesicle transport	The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.	got7fsn_ti	anterograde dense core granule trafficking|anterograde dense core granule transport													biological_process											owl:Class	
GO:0032536	biolink:NamedThing	regulation of cell projection size	A process that modulates the size of a cell projection.	got7fsn_ti														biological_process											owl:Class	
GO:0052715	biolink:NamedThing	mannosyl-diinositol phosphorylceramide phospholipase activity	Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol.	got7fsn_ti							ai	2011-08-05T08:02:57Z						molecular_function											owl:Class	
GO:0051610	biolink:NamedThing	serotonin uptake	The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.	got7fsn_ti	5-HT uptake|5HT uptake|5-hydroxytryptamine uptake|serotonin import													biological_process											owl:Class	
GO:0086100	biolink:NamedThing	endothelin receptor signaling pathway	A series of molecular signals initiated by an endothelin receptor binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	endothelin signaling pathway						bf							biological_process											owl:Class	
GO:0006728	biolink:NamedThing	pteridine biosynthetic process	The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.	got7fsn_ti	pteridine formation|pterin biosynthesis|pterin biosynthetic process|pteridine synthesis|pteridine biosynthesis|pteridine anabolism													biological_process											owl:Class	
GO:1990181	biolink:NamedThing	acetyl-CoA biosynthetic process from pantothenate	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA.	got7fsn_ti	acetyl-CoA synthesis from pantothenate|acetyl-CoA anabolism from pantothenate|acetyl-CoA formation from pantothenate						mah	2013-08-30T16:20:44Z						biological_process											owl:Class	
GO:0044482	biolink:NamedThing	envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism.	got7fsn_ti	envenomation resulting in blood vessel ECM, causing hemorrhagic damage in other organism						jl	2012-01-19T03:12:04Z						biological_process											owl:Class	
GO:0099503	biolink:NamedThing	secretory vesicle	A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.	got7fsn_ti														cellular_component											owl:Class	
GO:0043838	biolink:NamedThing	phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity	Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol.	got7fsn_ti	phosphoethanolamine transferase|EptB				Note that Kdo is an abbreviation for 3-deoxy-D-manno-oct-2-ulosonic acid.									molecular_function											owl:Class	
GO:0033118	biolink:NamedThing	esterosome membrane	The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes.	got7fsn_ti														cellular_component											owl:Class	
GO:0034853	biolink:NamedThing	2,4,4-trimethyl-3-oxopentanoate decarboxylase activity	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2.	got7fsn_ti												UM-BBD_reactionID:r1278		molecular_function											owl:Class	
GO:0035841	biolink:NamedThing	new growing cell tip	A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth.	got7fsn_ti	post-NETO new cell end|new cell tip after activation of bipolar cell growth|post-new end take-off new cell tip|post-NETO new cell tip						bf	2011-05-06T01:35:07Z						cellular_component											owl:Class	
GO:0009522	biolink:NamedThing	photosystem I	A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation).	got7fsn_ti														cellular_component											owl:Class	
GO:0018845	biolink:NamedThing	2-hydroxychromene-2-carboxylate isomerase activity	Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.	got7fsn_ti												EC:5.99.1.4|UM-BBD_reactionID:r0337|MetaCyc:RXNN-386|RHEA:27401|KEGG_REACTION:R05137		molecular_function											owl:Class	
GO:0018494	biolink:NamedThing	carvone reductase activity	Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone.	got7fsn_ti												MetaCyc:RXN-9419|MetaCyc:RXN-9403|EC:1.3.99.25|UM-BBD_reactionID:r0732		molecular_function											owl:Class	
GO:0102198	biolink:NamedThing	L-idonate 5-dehydrogenase activity (NAD-dependent)	Catalysis of the reaction: L-idonate + NAD = 5-dehydro-D-gluconate + NADH + H+.	got7fsn_ti												EC:1.1.1.366|MetaCyc:RXN-12107|RHEA:21172		molecular_function											owl:Class	
GO:0015824	biolink:NamedThing	proline transport	The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-proline transport													biological_process											owl:Class	
GO:0050476	biolink:NamedThing	acetylenedicarboxylate decarboxylase activity	Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate.	got7fsn_ti	acetylenedicarboxylate hydrase activity|acetylenedicarboxylate carboxy-lyase activity|acetylenedicarboxylate carboxy-lyase (pyruvate-forming)|acetylenedicarboxylate hydratase activity											EC:4.1.1.78|MetaCyc:4.1.1.78-RXN|RHEA:17733		molecular_function											owl:Class	
GO:0003849	biolink:NamedThing	3-deoxy-7-phosphoheptulonate synthase activity	Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate.	got7fsn_ti	7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate|3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase activity|D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) activity|7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity|2-dehydro-3-deoxyphosphoheptonate aldolase activity|KDPH synthase activity|phospho-2-keto-3-deoxyheptanoate aldolase activity|3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase activity|KDPH synthetase activity|DS-Mn activity|DAHP synthase activity|3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase activity|deoxy-D-arabino-heptulosonate-7-phosphate synthetase activity|DHAP synthase activity|phospho-2-keto-3-deoxyheptonate aldolase activity|phospho-2-oxo-3-deoxyheptonate aldolase activity|2-dehydro-3-deoxy-phosphoheptonate aldolase activity|D-erythrose-4-phosphate-lyase activity|DAH7-P synthase activity|2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase activity|DS-Co activity|phospho-2-keto-3-deoxyheptonic aldolase activity|7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity|phospho-2-dehydro-3-deoxyheptonate aldolase activity|phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)				Note that this function was formerly EC:4.1.2.15.							KEGG_REACTION:R01826|EC:2.5.1.54|MetaCyc:DAHPSYN-RXN|RHEA:14717		molecular_function											owl:Class	
GO:0090250	biolink:NamedThing	cell-cell adhesion involved in establishment of planar polarity	The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity.	got7fsn_ti							tb	2010-01-22T11:28:03Z						biological_process											owl:Class	
GO:0102868	biolink:NamedThing	24-epi-campsterol desaturase activity	Catalysis of the reaction: 24-epi-campesterol + NADPH + H+ + O2 <=> brassicasterol + NADP + 2 H2O.	got7fsn_ti												MetaCyc:RXN-8352		molecular_function											owl:Class	
GO:0033831	biolink:NamedThing	kojibiose phosphorylase activity	Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose.	got7fsn_ti	2-alpha-D-glucosyl-D-glucose:phosphate beta-D-glucosyltransferase activity											EC:2.4.1.230|MetaCyc:2.4.1.230-RXN|KEGG_REACTION:R07264|RHEA:11176		molecular_function											owl:Class	
GO:0052156	biolink:NamedThing	modulation by symbiont of host T-cell mediated immune response	Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction										GO:0052295			biological_process											owl:Class	
GO:0032165	biolink:NamedThing	prospore septin filament array	Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation.	got7fsn_ti														cellular_component											owl:Class	
GO:0032160	biolink:NamedThing	septin filament array	Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans.	got7fsn_ti	septin bar													cellular_component											owl:Class	
GO:0090127	biolink:NamedThing	positive regulation of synapse maturation by synaptic transmission	Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse.	got7fsn_ti							tb	2009-12-07T02:57:21Z						biological_process											owl:Class	
GO:0090129	biolink:NamedThing	positive regulation of synapse maturation	Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.	got7fsn_ti							tb	2009-12-07T03:00:58Z						biological_process											owl:Class	
GO:0008929	biolink:NamedThing	methylglyoxal synthase activity	Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate.	got7fsn_ti	glycerone-phosphate phospho-lyase (methylglyoxal-forming)|glycerone-phosphate phospho-lyase activity|methylglyoxal synthetase activity											EC:4.2.3.3|MetaCyc:METHGLYSYN-RXN|KEGG_REACTION:R01016|RHEA:17937		molecular_function											owl:Class	
GO:0071528	biolink:NamedThing	tRNA re-export from nucleus	The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.	got7fsn_ti	tRNA reexport from nucleus						mah	2010-01-07T04:17:05Z						biological_process											owl:Class	
GO:0006409	biolink:NamedThing	tRNA export from nucleus	The directed movement of tRNA from the nucleus to the cytoplasm.	got7fsn_ti	tRNA export out of nucleus|tRNA transport from nucleus to cytoplasm|tRNA export from cell nucleus|tRNA-nucleus export													biological_process											owl:Class	
GO:0006712	biolink:NamedThing	mineralocorticoid catabolic process	The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.	got7fsn_ti	mineralocorticoid catabolism|mineralocorticoid breakdown|mineralocorticoid degradation													biological_process											owl:Class	
GO:0018942	biolink:NamedThing	organometal metabolic process	The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.	got7fsn_ti	organometal metabolism													biological_process											owl:Class	
GO:0080064	biolink:NamedThing	4,4-dimethyl-9beta,19-cyclopropylsterol oxidation	A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O.	got7fsn_ti	4,4-dimethyl-9beta,19-cyclopropylsterol-4alpha-methyl oxidase activity						dhl	2009-04-13T03:39:58Z						biological_process											owl:Class	
GO:1990390	biolink:NamedThing	protein K33-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.	got7fsn_ti							sp	2014-06-03T12:22:05Z						biological_process											owl:Class	
GO:0042568	biolink:NamedThing	insulin-like growth factor binary complex	A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development.	got7fsn_ti	IGF binary complex													cellular_component											owl:Class	
GO:0035935	biolink:NamedThing	androgen secretion	The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates.	got7fsn_ti							bf	2011-07-20T01:11:31Z						biological_process											owl:Class	
GO:0061245	biolink:NamedThing	establishment or maintenance of bipolar cell polarity	Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.	got7fsn_ti							dph	2010-08-23T09:42:05Z						biological_process											owl:Class	
GO:0035163	biolink:NamedThing	embryonic hemocyte differentiation	The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.	got7fsn_ti	embryonic arthropod blood cell differentiation|embryonic hemocyte cell differentiation													biological_process											owl:Class	
GO:0090616	biolink:NamedThing	mitochondrial mRNA 3'-end processing	Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome.	got7fsn_ti							tb	2014-10-24T12:45:08Z						biological_process											owl:Class	
GO:0001176	biolink:NamedThing	transcriptional start site selection at bacterial-type RNA polymerase promoter	Any process involved in the selection of the specific location within the template strand of a bacterial-type RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	got7fsn_ti							krc	2011-06-20T01:48:56Z						biological_process											owl:Class	
GO:0120304	biolink:NamedThing	integument-mediated background adaptation	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20524					krc	2021-02-09T18:41:07Z						biological_process											owl:Class	
GO:0035334	biolink:NamedThing	Notch receptor processing, ligand-independent	The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.	got7fsn_ti	Notch S1 cleavage						bf	2010-02-26T02:32:46Z						biological_process											owl:Class	
GO:0016262	biolink:NamedThing	protein N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein.	got7fsn_ti	N-GlcNAc transferase activity|UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase activity|uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase activity										GO:0016253	EC:2.4.1.94|MetaCyc:2.4.1.94-RXN|RHEA:16533		molecular_function											owl:Class	
GO:0050449	biolink:NamedThing	casbene synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate.	got7fsn_ti	geranylgeranyl-diphosphate diphosphate-lyase (cyclizing)|casbene synthetase activity|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming)											MetaCyc:CASBENE-SYNTHASE-RXN|EC:4.2.3.8|KEGG_REACTION:R02064|RHEA:14901		molecular_function											owl:Class	
GO:0061294	biolink:NamedThing	mesonephric renal vesicle induction	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.	got7fsn_ti							dph	2010-09-03T12:57:59Z						biological_process											owl:Class	
GO:0102566	biolink:NamedThing	1-acyl dihydroxyacetone phosphate reductase activity	Catalysis of the reaction: 1-oleoylglycerone 3-phosphate + NADPH + H+ = 1-oleoyl-sn-glycero-3-phosphate + NADP.	got7fsn_ti												EC:1.1.1.101|MetaCyc:RXN-15046		molecular_function											owl:Class	
GO:0004146	biolink:NamedThing	dihydrofolate reductase activity	Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.	got7fsn_ti	dihydrofolic acid reductase activity|5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity|dihydrofolate reductase:thymidylate synthase activity|folic acid reductase activity|thymidylate synthetase-dihydrofolate reductase activity|NADPH-dihydrofolate reductase activity|7,8-dihydrofolate reductase activity|dihydrofolate reduction|tetrahydrofolate dehydrogenase activity|dihydrofolic reductase activity|folic reductase activity|DHFR|pteridine reductase:dihydrofolate reductase activity											MetaCyc:DIHYDROFOLATEREDUCT-RXN|RHEA:15009|Reactome:R-HSA-1497794|EC:1.5.1.3		molecular_function											owl:Class	
GO:0004168	biolink:NamedThing	dolichol kinase activity	Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.	got7fsn_ti	CTP:dolichol O-phosphotransferase activity|dolichol phosphokinase activity											EC:2.7.1.108|Reactome:R-HSA-446195|RHEA:13133|Reactome:R-HSA-4755600|MetaCyc:DOLICHOL-KINASE-RXN		molecular_function											owl:Class	
GO:0033982	biolink:NamedThing	3-dehydro-L-gulonate-6-phosphate decarboxylase activity	Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2).	got7fsn_ti	3-keto-L-gulonate 6-phosphate decarboxylase activity|3-dehydro-L-gulonate-6-phosphate carboxy-lyase activity|SgaH|3-dehydro-L-gulonate-6-phosphate carboxy-lyase (L-xylulose-5-phosphate-forming) activity|KGPDC|SgbH|UlaD											MetaCyc:RXN0-705|KEGG_REACTION:R07125|RHEA:14353|EC:4.1.1.85		molecular_function											owl:Class	
GO:0061340	biolink:NamedThing	establishment or maintenance of monopolar cell polarity regulating cell shape	Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell.	got7fsn_ti							dph	2010-09-29T09:13:55Z						biological_process											owl:Class	
GO:0014881	biolink:NamedThing	regulation of myofibril size	Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.	got7fsn_ti	change of myofibril size													biological_process											owl:Class	
GO:0014743	biolink:NamedThing	regulation of muscle hypertrophy	Any process that modulates the frequency, rate or extent of muscle hypertrophy.	got7fsn_ti														biological_process											owl:Class	
GO:0090163	biolink:NamedThing	establishment of epithelial cell planar polarity	The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue.	got7fsn_ti							tb	2009-12-08T08:59:57Z						biological_process											owl:Class	
GO:0015621	biolink:NamedThing	ferric triacetylfusarinine C transmembrane transporter activity	Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042495	biolink:NamedThing	detection of triacyl bacterial lipopeptide	The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups.	got7fsn_ti	perception of triacylated bacterial lipopeptide|detection of triacylated bacterial lipoprotein|perception of triacylated bacterial lipoprotein				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.									biological_process											owl:Class	
GO:0070340	biolink:NamedThing	detection of bacterial lipopeptide	The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0140023	biolink:NamedThing	tRNA adenosine deamination to inosine	The removal of an amine group from an adenosine to produce inosine within a tRNA molecule.	got7fsn_ti	A-to-I tRNA editing						pg	2017-04-26T05:56:51Z						biological_process											owl:Class	
GO:0140616	biolink:NamedThing	iodotyrosine deiodinase activity	Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH.	got7fsn_ti	monoiodotyrosine deiodinase activity|iodotyrosine deiodase activity|iodotyrosine deiodinase activity|iodide peroxidase-tyrosine iodinase activity|tyrosine iodinase activity	https://github.com/geneontology/go-ontology/issues/21027					pg	2021-03-08T15:36:42Z				RHEA:32479|EC:1.21.1.1		molecular_function											owl:Class	
GO:0046026	biolink:NamedThing	precorrin-4 C11-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5.	got7fsn_ti	S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase activity|CobM											EC:2.1.1.133|RHEA:22012|MetaCyc:2.1.1.133-RXN		molecular_function											owl:Class	
GO:0008352	biolink:NamedThing	katanin complex	A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).	got7fsn_ti					Consider also annotating to the molecular function term 'microtubule-severing ATPase activity ; GO:0008568'.									cellular_component											owl:Class	
GO:0070692	biolink:NamedThing	CTDK-1 complex	A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).	got7fsn_ti	Ctk complex|CTDK-I complex|trimeric positive transcription elongation factor complex b|C-terminal domain kinase I complex						mah	2009-06-03T03:18:04Z						cellular_component											owl:Class	
GO:0047300	biolink:NamedThing	pyridoxamine-pyruvate transaminase activity	Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal.	got7fsn_ti	pyridoxamine-pyruvate aminotransferase activity|pyridoxamine:pyruvate aminotransferase activity|pyridoxamine--pyruvate aminotransferase activity|pyridoxamineu-pyruvic transaminase activity|pyridoxamine-pyruvic transaminase											KEGG_REACTION:R01712|MetaCyc:2.6.1.30-RXN|RHEA:12841|EC:2.6.1.30		molecular_function											owl:Class	
GO:0032071	biolink:NamedThing	regulation of endodeoxyribonuclease activity	Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	got7fsn_ti	endodeoxyribonuclease regulator													biological_process											owl:Class	
GO:0097070	biolink:NamedThing	ductus arteriosus closure	The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs.	got7fsn_ti							pr	2011-06-15T04:00:46Z						biological_process											owl:Class	
GO:0060619	biolink:NamedThing	cell migration involved in mammary placode formation	The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.	got7fsn_ti							dph	2009-05-18T09:41:49Z						biological_process											owl:Class	
GO:0031665	biolink:NamedThing	negative regulation of lipopolysaccharide-mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.	got7fsn_ti	inhibition of lipopolysaccharide-mediated signaling pathway|downregulation of lipopolysaccharide-mediated signaling pathway|down-regulation of lipopolysaccharide-mediated signaling pathway|down regulation of lipopolysaccharide-mediated signaling pathway|negative regulation of LPS-mediated signaling pathway|negative regulation of lipopolysaccharide-mediated signalling pathway													biological_process											owl:Class	
GO:0071494	biolink:NamedThing	cellular response to UV-C	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.	got7fsn_ti	cellular response to UV-C radiation stimulus|cellular response to UV-C light stimulus|cellular response to germicidal ultraviolet radiation stimulus|cellular response to UVC radiation stimulus|cellular response to UVC light stimulus|cellular response to shortwave ultraviolet light stimulus|cellular response to shortwave ultraviolet radiation stimulus|cellular response to germicidal ultraviolet light stimulus						mah	2009-12-18T02:22:01Z						biological_process											owl:Class	
GO:0080096	biolink:NamedThing	phosphatidate-sterol O-acyltransferase activity	Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate.	got7fsn_ti							dhl	2009-04-23T03:41:42Z						molecular_function											owl:Class	
GO:0035061	biolink:NamedThing	interchromatin granule	A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).	got7fsn_ti	ICG											NIF_Subcellular:sao1049471211		cellular_component											owl:Class	
GO:0003027	biolink:NamedThing	regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling	The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.	got7fsn_ti	carotid body chemoreceptor response to lowering of systemic arterial blood pressure|carotid body chemoreceptor regulation of systemic arterial blood pressure|vagal reflex|regulation of systemic arterial blood pressure by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0022038	biolink:NamedThing	corpus callosum development	The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.	got7fsn_ti														biological_process											owl:Class	
GO:0070073	biolink:NamedThing	clustering of voltage-gated calcium channels	The process in which voltage-gated calcium channels become localized together in high densities.	got7fsn_ti	clustering of voltage-dependent calcium channels|voltage-gated calcium channel clustering|clustering of voltage gated calcium channels													biological_process											owl:Class	
GO:0044026	biolink:NamedThing	DNA hypermethylation	An increase in the epigenetic methylation of cytosine and adenosine residues in DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0050879	biolink:NamedThing	multicellular organismal movement	Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism.	got7fsn_ti														biological_process											owl:Class	
GO:1900549	biolink:NamedThing	N',N'',N'''-triacetylfusarinine C metabolic process	The chemical reactions and pathways involving N',N'',N'''-triacetylfusarinine C.	got7fsn_ti	N',N'',N'''-triacetylfusarinine C metabolism						di	2012-05-15T12:59:06Z						biological_process											owl:Class	
GO:0007370	biolink:NamedThing	ventral furrow formation	Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0018816	biolink:NamedThing	2-hydroxyisobutyrate dehydratase activity	Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate.	got7fsn_ti												UM-BBD_reactionID:r0618		molecular_function											owl:Class	
GO:0010564	biolink:NamedThing	regulation of cell cycle process	Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.	got7fsn_ti														biological_process											owl:Class	
GO:0010301	biolink:NamedThing	xanthoxin dehydrogenase activity	Catalysis of the reaction: NAD(+) + xanthoxin = (+)-abscisic aldehyde + H(+) + NADH.	got7fsn_ti	xanthoxin oxidase activity|xanthoxin:NAD+ oxidoreductase activity|ABA2										GO:0033710	MetaCyc:1.1.1.288-RXN|RHEA:12548|KEGG_REACTION:R06954|EC:1.1.1.288		molecular_function											owl:Class	
GO:0014047	biolink:NamedThing	glutamate secretion	The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0050825	biolink:NamedThing	ice binding	Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.	got7fsn_ti	ice nucleation activity|antifreeze activity|ice nucleation inhibitor activity|ice crystal binding													molecular_function											owl:Class	
GO:0047184	biolink:NamedThing	1-acylglycerophosphocholine O-acyltransferase activity	Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.	got7fsn_ti	1-acyl-sn-glycero-3-phosphocholine acyltransferase activity|lysolecithin acyltransferase activity|lysophosphatide acyltransferase activity|lysophosphatidylcholine acyltransferase activity|acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase activity|acyl coenzyme A-monoacylphosphatidylcholine acyltransferase activity|acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity										GO:0000507	Reactome:R-HSA-1482794|MetaCyc:2.3.1.23-RXN|EC:2.3.1.23|RHEA:12937		molecular_function											owl:Class	
GO:0006478	biolink:NamedThing	peptidyl-tyrosine sulfation	The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine.	got7fsn_ti	peptidyl-tyrosine sulphation											RESID:AA0172		biological_process											owl:Class	
GO:0047081	biolink:NamedThing	3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity	Catalysis of the reaction: O2 + NADPH + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NADP+ + 2-(acetamidomethylene)succinate.	got7fsn_ti	methylhydroxypyridinecarboxylate oxidase activity|methylhydroxypyridine carboxylate dioxygenase activity|3-hydroxy-3-methylpyridinecarboxylate dioxygenase activity|2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase activity|3-hydroxy-2-methylpyridine-5-carboxylate,NADPH:oxygen oxidoreductase (decyclizing)											RHEA:10864|MetaCyc:1.14.12.4-RXN|EC:1.14.13.242		molecular_function											owl:Class	
GO:0047708	biolink:NamedThing	biotinidase activity	Catalysis of the reaction: biotin amide + H2O = biotin + NH3.	got7fsn_ti	biotin-amide amidohydrolase activity|amidohydrolase biotinidase activity											Reactome:R-HSA-4167509|Reactome:R-HSA-4225086|MetaCyc:BIOTINIDASE-RXN|Reactome:R-HSA-3325540|Reactome:R-HSA-3076905|RHEA:13081|EC:3.5.1.12		molecular_function											owl:Class	
GO:0047151	biolink:NamedThing	methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+.	got7fsn_ti	methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH-oxidizing) activity|5,10-methylenetetrahydrofolate:tRNA-UPsiC (uracil-5-)-methyl-transferase activity|folate-dependent ribothymidyl synthase activity|5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyltransferase activity|methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase activity											KEGG_REACTION:R03704|MetaCyc:2.1.1.74-RXN|RHEA:16873|EC:2.1.1.74		molecular_function											owl:Class	
GO:0008728	biolink:NamedThing	GTP diphosphokinase activity	Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.	got7fsn_ti	ATP-GTP 3'-diphosphotransferase activity|guanosine pentaphosphate synthetase activity|GPSII|guanosine 5',3'-polyphosphate synthetase activity|stringent factor activity|GPSI|(p)ppGpp synthetase II|GTP pyrophosphokinase activity|guanosine 3',5'-polyphosphate synthase activity|ATP:GTP 3'-diphosphotransferase activity|ppGpp synthetase I activity|(p)ppGpp synthetase I											MetaCyc:GTPPYPHOSKIN-RXN|EC:2.7.6.5|RHEA:22088		molecular_function											owl:Class	
GO:0051013	biolink:NamedThing	microtubule severing	The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends.	got7fsn_ti	microtubule severing activity													biological_process											owl:Class	
GO:0010841	biolink:NamedThing	positive regulation of circadian sleep/wake cycle, wakefulness	Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.	got7fsn_ti														biological_process											owl:Class	
GO:0003349	biolink:NamedThing	epicardium-derived cardiac endothelial cell differentiation	The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.	got7fsn_ti							dph	2009-12-01T11:17:49Z						biological_process											owl:Class	
GO:0032331	biolink:NamedThing	negative regulation of chondrocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.	got7fsn_ti	down-regulation of chondrocyte differentiation|down regulation of chondrocyte differentiation|inhibition of chondrocyte differentiation|downregulation of chondrocyte differentiation													biological_process											owl:Class	
GO:0061957	biolink:NamedThing	NVT complex	A protein complex that is capable of contributing to protein localization by the NVT pathway. In fission yeast, the Nvt complex consists of Ape2, Lap2 and Nbr1.	got7fsn_ti							dph	2017-12-01T17:01:17Z						cellular_component											owl:Class	
GO:0002395	biolink:NamedThing	immune response in nasopharyngeal-associated lymphoid tissue	An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids.	got7fsn_ti	immune response in NALT													biological_process											owl:Class	
GO:0032031	biolink:NamedThing	myosin I head/neck binding	Binding to the head/neck region of a myosin I heavy chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0033739	biolink:NamedThing	preQ1 synthase activity	Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH.	got7fsn_ti	preQ0 oxidoreductase activity|QueF|queuine:NADP+ oxidoreductase activity|7-cyano-7-deazaguanine reductase activity|preQ0 reductase activity|7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity|queuine synthase activity|YkvM											EC:1.7.1.13|KEGG_REACTION:R07605|RHEA:13409|MetaCyc:RXN0-4022		molecular_function											owl:Class	
GO:1990713	biolink:NamedThing	survivin complex	A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC).	got7fsn_ti	Baculoviral IAP repeat-containing protein 5 complex|survivin homodimer complex				An example of this is BIRC5 in human (UniProt symbol O15392) in PMID:10949038 (inferred from physical interaction).		bhm	2015-03-26T14:21:46Z						cellular_component											owl:Class	
GO:0015680	biolink:NamedThing	protein maturation by copper ion transfer	A process that contributes to the delivery of copper ions to a target protein.	got7fsn_ti	intracellular copper ion delivery|intracellular copper ion transport|intracellular copper delivery													biological_process											owl:Class	
GO:0034813	biolink:NamedThing	benzo(a)pyrene 7,8-dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol.	got7fsn_ti												UM-BBD_reactionID:r1137|EC:1.13.11.-		molecular_function											owl:Class	
GO:0030215	biolink:NamedThing	semaphorin receptor binding	Binding to a semaphorin receptor.	got7fsn_ti	plexin binding|plexin ligand|semaphorin receptor ligand													molecular_function											owl:Class	
GO:0014824	biolink:NamedThing	artery smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.	got7fsn_ti														biological_process											owl:Class	
GO:0102709	biolink:NamedThing	S-adenosyl-L-methionine:N,N-dimethyl-beta-alanine N-methyltransferase activity	Catalysis of the reaction: N,N-dimethyl-beta-alanine + S-adenosyl-L-methionine  = H+ + beta-alanine betaine + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-6464		molecular_function											owl:Class	
GO:0120274	biolink:NamedThing	virus coreceptor activity	Combining with a virus component, and in cooperation with a nearby primary receptor, initiating a change in cell activity.	got7fsn_ti	viral coreceptor activity	https://github.com/geneontology/go-ontology/issues/20137					krc	2020-10-20T18:32:45Z						molecular_function											owl:Class	
GO:0044637	biolink:NamedThing	envenomation resulting in negative regulation of complement activation, classical pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism.	got7fsn_ti							jl	2012-07-05T04:46:56Z						biological_process											owl:Class	
GO:0043958	biolink:NamedThing	acryloyl-CoA reductase activity	Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein.	got7fsn_ti	acrylyl-CoA reductase (NADH)|acryloyl-coenzyme A reductase activity|propionyl-CoA dehydrogenase				Note that this function is part of the process of L-alanine fermentation to propionate.							MetaCyc:RXN-8568|EC:1.3.99.3|RHEA:34471		molecular_function											owl:Class	
GO:1990425	biolink:NamedThing	ryanodine receptor complex	A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom.	got7fsn_ti	RyR				An example of this is RyR1 in rabbit (P11716) in PMID:2550460 (inferred from electron microscopy).		anm	2014-07-24T09:36:41Z						cellular_component											owl:Class	
GO:0018737	biolink:NamedThing	2-ketocyclohexane-1-carboxyl-CoA hydrolase activity	Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0193		molecular_function											owl:Class	
GO:0033511	biolink:NamedThing	luteolin biosynthetic process	The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.	got7fsn_ti	luteolin anabolism|luteolin formation|luteolin synthesis|luteolin biosynthesis											MetaCyc:PWY-5060		biological_process											owl:Class	
GO:0035691	biolink:NamedThing	macrophage migration inhibitory factor signaling pathway	A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	macrophage migration inhibitory factor signalling pathway|MIF signaling pathway						bf	2011-02-25T11:31:21Z						biological_process											owl:Class	
GO:0038168	biolink:NamedThing	epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via I-kappaB-kinase (IKK)-dependent activation of the transcription factor NF-kappaB.	got7fsn_ti	EGFR signaling pathway via IKK-dependent activation of NF-kappaB|EGFR signaling pathway via IKK/NF-kappaB cascade						bf	2012-05-15T12:01:09Z						biological_process											owl:Class	
GO:0043960	biolink:NamedThing	L-erythro-3-methylmalyl-CoA dehydratase activity	Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O.	got7fsn_ti														molecular_function											owl:Class	
GO:0102781	biolink:NamedThing	isofucosterol hydroxylase activity	Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH <=> (22alpha)-hydroxy-isofucosterol + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-7877		molecular_function											owl:Class	
GO:0042862	biolink:NamedThing	achromobactin catabolic process	The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore.	got7fsn_ti	achromobactin degradation|achromobactin catabolism|achromobactin breakdown													biological_process											owl:Class	
GO:0102911	biolink:NamedThing	(-)-secoisolariciresinol dehydrogenase activity	Catalysis of the reaction: (-)-secoisolariciresinol + NAD <=> H+ + (-)-lactol + NADH.	got7fsn_ti												MetaCyc:RXN-8680		molecular_function											owl:Class	
GO:0070774	biolink:NamedThing	phytoceramidase activity	Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine.	got7fsn_ti							mah	2009-07-02T10:52:42Z				Reactome:R-HSA-428262|MetaCyc:CERAMIDASE-YEAST-RXN|KEGG_REACTION:R06528		molecular_function											owl:Class	
GO:0050170	biolink:NamedThing	peptidyl-glutaminase activity	Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3.	got7fsn_ti	peptidoglutaminase activity|peptidyl-L-glutamine amidohydrolase activity|peptideglutaminase activity|peptidoglutaminase I activity											MetaCyc:PEPTIDYL-GLUTAMINASE-RXN|RHEA:10032|EC:3.5.1.43		molecular_function											owl:Class	
GO:0016419	biolink:NamedThing	S-malonyltransferase activity	Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule.	got7fsn_ti												EC:2.3.1.39		molecular_function											owl:Class	
GO:0061446	biolink:NamedThing	endocardial cushion cell fate determination	The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	got7fsn_ti							dph	2012-03-13T09:22:13Z						biological_process											owl:Class	
GO:0034188	biolink:NamedThing	apolipoprotein A-I receptor activity	Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0030226	biolink:NamedThing	apolipoprotein receptor activity	Combining with an apolipoprotein to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0018365	biolink:NamedThing	protein-serine epimerase activity	Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine.	got7fsn_ti	protein-serine racemase activity											RHEA:10660|EC:5.1.1.16|MetaCyc:5.1.1.16-RXN		molecular_function											owl:Class	
GO:0016855	biolink:NamedThing	racemase and epimerase activity, acting on amino acids and derivatives	Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid.	got7fsn_ti												EC:5.1.1.-		molecular_function											owl:Class	
GO:0035126	biolink:NamedThing	post-embryonic genitalia morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.	got7fsn_ti	post-embryonic genital morphogenesis													biological_process											owl:Class	
GO:0001616	biolink:NamedThing	growth hormone secretagogue receptor activity	Combining with ghrelin to initiate a change in cell activity.	got7fsn_ti	ghrelin receptor activity													molecular_function											owl:Class	
GO:0140506	biolink:NamedThing	endoplasmic reticulum-autophagosome adaptor activity	The binding activity of a molecule that brings together an ER membrane and an autophagosome during reticulophagy.	got7fsn_ti	autophagosome-endoplasmic reticulum anchor|autophagosome-ER anchor|ER- autophagosome anchor	https://github.com/geneontology/go-ontology/issues/19873					pg	2020-08-27T11:04:43Z						molecular_function											owl:Class	
GO:0051665	biolink:NamedThing	membrane raft localization	Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	got7fsn_ti	lipid raft localization|membrane raft localisation|establishment and maintenance of membrane raft localization													biological_process											owl:Class	
GO:0033980	biolink:NamedThing	phosphonopyruvate decarboxylase activity	Catalysis of the reaction: 3-phosphonopyruvate + 2 H(+) = CO(2) + phosphonoacetaldehyde.	got7fsn_ti	3-phosphonopyruvate carboxy-lyase activity|3-phosphonopyruvate carboxy-lyase (2-phosphonoacetaldehyde-forming) activity											MetaCyc:4.1.1.82-RXN|KEGG_REACTION:R04053|RHEA:20768|EC:4.1.1.82		molecular_function											owl:Class	
GO:0040039	biolink:NamedThing	inductive cell migration	Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans.	got7fsn_ti														biological_process											owl:Class	
GO:0016617	biolink:NamedThing	4-oxoproline reductase activity	Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+.	got7fsn_ti	hydroxyproline oxidase activity|4-hydroxy-L-proline:NAD+ oxidoreductase activity|hydroxy-L-proline oxidase activity											MetaCyc:4-OXOPROLINE-REDUCTASE-RXN|RHEA:13601|EC:1.1.1.104		molecular_function											owl:Class	
GO:0018657	biolink:NamedThing	toluene 3-monooxygenase activity	Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene.	got7fsn_ti												EC:1.14.13.-|MetaCyc:TOLUENE-3-MONOOXYGENASE-RXN|UM-BBD_enzymeID:e0224		molecular_function											owl:Class	
GO:0005637	biolink:NamedThing	nuclear inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.	got7fsn_ti	nucleus inner membrane|inner nuclear membrane|inner envelope											NIF_Subcellular:sao1612527463		cellular_component											owl:Class	
GO:0001859	biolink:NamedThing	complement component C3dg receptor activity	Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0019552	biolink:NamedThing	glutamate catabolic process via 2-hydroxyglutarate	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP.	got7fsn_ti	glutamate fermentation via 2-hydroxyglutarate											MetaCyc:P162-PWY		biological_process											owl:Class	
GO:0019670	biolink:NamedThing	anaerobic glutamate catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP.	got7fsn_ti	glutamate fermentation													biological_process											owl:Class	
GO:0002872	biolink:NamedThing	negative regulation of natural killer cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.	got7fsn_ti	down-regulation of natural killer cell tolerance induction|down regulation of natural killer cell tolerance induction|downregulation of natural killer cell tolerance induction|negative regulation of NK cell tolerance induction|inhibition of natural killer cell tolerance induction													biological_process											owl:Class	
GO:0043917	biolink:NamedThing	ribose 1,5-bisphosphate isomerase activity	Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.	got7fsn_ti	ribose-1,5-bisphosphate isomerase activity											MetaCyc:RXN-8801|EC:5.3.1.29|RHEA:32243		molecular_function											owl:Class	
GO:0090581	biolink:NamedThing	protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0102067	biolink:NamedThing	geranylgeranyl diphosphate reductase activity	Catalysis of the reaction: (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + 3 NADP <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + 3 NADPH + 3 H+.	got7fsn_ti												MetaCyc:RXN-10625|RHEA:26229|EC:1.3.1.83		molecular_function											owl:Class	
GO:0036448	biolink:NamedThing	cellular response to glucose-phosphate stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate.	got7fsn_ti							bf	2013-10-31T11:20:08Z						biological_process											owl:Class	
GO:0036447	biolink:NamedThing	cellular response to sugar-phosphate stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate.	got7fsn_ti	cellular response to presence of non-metabolizable sugars						bf	2013-10-31T11:18:09Z						biological_process											owl:Class	
GO:0046784	biolink:NamedThing	viral mRNA export from host cell nucleus	The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.	got7fsn_ti	intronless viral mRNA transport from nucleus to cytoplasm|intronless viral mRNA-nucleus export|intronless viral mRNA export out of nucleus|intronless viral mRNA export from host cell nucleus|intronless viral mRNA export from host nucleus													biological_process											owl:Class	
GO:0120249	biolink:NamedThing	lateral wall of outer hair cell	The lateral wall of an outer hair cell (OHC) is a unique trilaminate composite consisting of the plasma membrane, an underlying cytoskeletal network containing an actin-spectrin cortical lattice, and an adjacent system of circumferential lamellar organelles known as the subsurface cisternae.	got7fsn_ti	outer hair cell lateral wall|lateral wall of OHC|OHC lateral wall						krc	2020-08-27T23:53:44Z						cellular_component											owl:Class	
GO:0097574	biolink:NamedThing	lateral part of cell	The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells.	got7fsn_ti							pr	2014-02-26T13:27:27Z						cellular_component											owl:Class	
GO:0060594	biolink:NamedThing	mammary gland specification	The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes.	got7fsn_ti	mammary line specification						dph	2009-05-13T10:09:10Z						biological_process											owl:Class	
GO:0106186	biolink:NamedThing	cytoplasmic side of plasma membrane, cell tip	The leaflet the plasma membrane at the cell tip that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	got7fsn_ti							hjd	2019-05-01T17:48:02Z						cellular_component											owl:Class	
GO:0009898	biolink:NamedThing	cytoplasmic side of plasma membrane	The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	got7fsn_ti	internal leaflet of plasma membrane|juxtamembrane|internal side of plasma membrane													cellular_component											owl:Class	
GO:0060958	biolink:NamedThing	endocardial cell development	The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.	got7fsn_ti							dph	2009-09-29T03:26:59Z						biological_process											owl:Class	
GO:0042169	biolink:NamedThing	SH2 domain binding	Binding to a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class.	got7fsn_ti														molecular_function											owl:Class	
GO:0021516	biolink:NamedThing	dorsal spinal cord development	The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.	got7fsn_ti														biological_process											owl:Class	
GO:0004121	biolink:NamedThing	cystathionine beta-lyase activity	Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.	got7fsn_ti	beta-cystathionase activity|cystathionine L-homocysteine-lyase (deaminating)|L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)|beta C-S lyase activity|L-cystathionine L-homocysteine-lyase (deaminating)|cystine lyase activity										GO:0008799	EC:4.4.1.8|RHEA:13965|MetaCyc:CYSTATHIONINE-BETA-LYASE-RXN		molecular_function											owl:Class	
GO:0051393	biolink:NamedThing	alpha-actinin binding	Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.	got7fsn_ti	nonmuscle alpha-actinin binding|alpha-actinin 4 binding|alpha-actinin 1 binding										GO:0051372			molecular_function											owl:Class	
GO:0042805	biolink:NamedThing	actinin binding	Binding to actinin, any member of a family of proteins that crosslink F-actin.	got7fsn_ti	capZ binding|beta-actinin binding										GO:0051406			molecular_function											owl:Class	
GO:0001861	biolink:NamedThing	complement component C4b receptor activity	Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:1990169	biolink:NamedThing	stress response to copper ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus.	got7fsn_ti	response to copper ion stress|stress response to copper|response to copper toxicity						pr	2013-08-14T12:52:05Z						biological_process											owl:Class	
GO:0046688	biolink:NamedThing	response to copper ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	got7fsn_ti	response to copper|copper sensitivity/resistance													biological_process											owl:Class	
GO:0044475	biolink:NamedThing	envenomation resulting in negative regulation of high voltage-gated calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:28:11Z						biological_process											owl:Class	
GO:0039611	biolink:NamedThing	suppression by virus of host translation initiation factor activity	Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor.	got7fsn_ti	inhibition of activity of host translation initiation factor|inactivation of eIF2 activity|Inhibition of host translation factors by virus|suppression by virus of host EIF-4E activity						bf	2012-07-06T10:27:16Z						biological_process											owl:Class	
GO:0033732	biolink:NamedThing	pyrroloquinoline-quinone synthase activity	Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone.	got7fsn_ti	6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) activity|PqqC											EC:1.3.3.11|KEGG_REACTION:R07353|RHEA:10692|MetaCyc:1.3.3.11-RXN		molecular_function											owl:Class	
GO:0044061	biolink:NamedThing	modulation by symbiont of host excretion	The alteration by a symbiont organism of the functioning of excretion, the elimination by the host organism of the waste products that arise as a result of metabolic activity.	got7fsn_ti	regulation by symbiont of host excretion													biological_process											owl:Class	
GO:1990263	biolink:NamedThing	spore wall assembly MAPK cascade	A MAPK cascade that occurs as a result of deprivation of nourishment.	got7fsn_ti	MAPK cascade involved in nutrient response signaling|MAPK cascade in response to starvation						al	2014-01-09T12:27:52Z						biological_process											owl:Class	
GO:0034718	biolink:NamedThing	SMN-Gemin2 complex	A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0055076	biolink:NamedThing	transition metal ion homeostasis	Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	got7fsn_ti														biological_process											owl:Class	
GO:0071463	biolink:NamedThing	cellular response to humidity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.	got7fsn_ti							mah	2009-12-18T11:33:55Z						biological_process											owl:Class	
GO:0010064	biolink:NamedThing	embryonic shoot morphogenesis	The process in which the anatomical structures of embryonic shoot are generated and organized.	got7fsn_ti	primary shoot system morphogenesis													biological_process											owl:Class	
GO:0031886	biolink:NamedThing	type 1 member 3 taste receptor binding	Binding to a type 1 member 3 taste receptor.	got7fsn_ti	sweet taste receptor binding|type 1 member 3 taste receptor ligand													molecular_function											owl:Class	
GO:0050432	biolink:NamedThing	catecholamine secretion	The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	got7fsn_ti														biological_process											owl:Class	
GO:0072566	biolink:NamedThing	chemokine (C-X-C motif) ligand 1 production	The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CXCL1 production|SCYB1 production|KC production|keratinocyte derived chemokine production						mah	2011-01-31T11:31:58Z						biological_process											owl:Class	
GO:1900339	biolink:NamedThing	regulation of methane biosynthetic process from formic acid	Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid.	got7fsn_ti							tt	2012-04-06T02:04:53Z						biological_process											owl:Class	
GO:0098773	biolink:NamedThing	skin epidermis development	The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0047456	biolink:NamedThing	2-methylisocitrate dehydratase activity	Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O.	got7fsn_ti	(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]											MetaCyc:4.2.1.99-RXN|EC:4.2.1.99|RHEA:17941|KEGG_REACTION:R04425		molecular_function											owl:Class	
GO:0090451	biolink:NamedThing	cotyledon boundary formation	The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained.	got7fsn_ti							tb	2012-09-19T10:26:54Z						biological_process											owl:Class	
GO:0090691	biolink:NamedThing	formation of plant organ boundary	The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.	got7fsn_ti							tb	2016-08-24T10:16:28Z						biological_process											owl:Class	
GO:0140677	biolink:NamedThing	molecular function activator activity	A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21782					pg	2021-07-07T07:24:16Z						molecular_function											owl:Class	
GO:0140431	biolink:NamedThing	DNA-(abasic site) binding	Binding to a DNA site that has neither a purine nor a pyrimidine base. Apurinic sites can form spontaneously or when DNA glycosylase removes a damaged base.	got7fsn_ti	DNA-(apurinic site) binding|DNA-(apurinic site/apyrimidinic site) binding|DNA AP site binding|DNA-(apyrimidinic site) binding	https://github.com/geneontology/go-ontology/issues/18878					pg	2020-02-19T05:30:09Z						molecular_function											owl:Class	
GO:1990667	biolink:NamedThing	PCSK9-AnxA2 complex	A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and annexin A2 (AnxA2).	got7fsn_ti	PCSK9.AnxA2 complex|PCSK9:ANXA2 complex|PCSK9-Annexin A2 complex						bf	2015-03-02T10:33:09Z						cellular_component											owl:Class	
GO:0035410	biolink:NamedThing	dihydrotestosterone 17-beta-dehydrogenase activity	Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH.	got7fsn_ti							bf	2010-03-24T10:48:41Z				EC:1.1.1.51		molecular_function											owl:Class	
GO:0002948	biolink:NamedThing	archaeosine synthase activity	Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.	got7fsn_ti	ArcS|glutamine:preQ0-tRNA amidinotransferase	https://github.com/geneontology/go-ontology/issues/20486					hjd	2014-08-11T10:33:59Z				Wikipedia:Archaeosine_synthase|EC:2.6.1.97|RHEA:54084		molecular_function											owl:Class	
GO:0006518	biolink:NamedThing	peptide metabolic process	The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.	got7fsn_ti	peptide metabolism													biological_process											owl:Class	
GO:1990486	biolink:NamedThing	anaerobic fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.	got7fsn_ti	anaerobic fatty acid degradation						tt	2014-09-20T17:25:48Z						biological_process											owl:Class	
GO:0033185	biolink:NamedThing	dolichol-phosphate-mannose synthase complex	A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively.	got7fsn_ti	DPM synthase complex|dolichyl-phosphate beta-D-mannosyltransferase complex													cellular_component											owl:Class	
GO:0035708	biolink:NamedThing	interleukin-4-dependent isotype switching to IgE isotypes	The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4).	got7fsn_ti	IL-4-dependent isotype switching to IgE isotypes						bf	2011-03-02T02:40:35Z						biological_process											owl:Class	
GO:0048289	biolink:NamedThing	isotype switching to IgE isotypes	The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.	got7fsn_ti	class switch recombination to IgE isotypes|isotype switch recombination to IgE isotypes|class switching to IgE isotypes													biological_process											owl:Class	
GO:0042998	biolink:NamedThing	positive regulation of Golgi to plasma membrane protein transport	Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.	got7fsn_ti	activation of Golgi to plasma membrane protein transport|upregulation of Golgi to plasma membrane protein transport|stimulation of Golgi to plasma membrane protein transport|up-regulation of Golgi to plasma membrane protein transport|up regulation of Golgi to plasma membrane protein transport													biological_process											owl:Class	
GO:0031592	biolink:NamedThing	centrosomal corona	An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.	got7fsn_ti					Note that the centrosomal corona has been observed in Dictyostelium, and is the functional equivalent of pericentriolar material.									cellular_component											owl:Class	
GO:0071204	biolink:NamedThing	histone pre-mRNA 3'end processing complex	A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.	got7fsn_ti	histone 3'end pre-mRNA complex						mah	2009-11-25T11:11:02Z						cellular_component											owl:Class	
GO:0061729	biolink:NamedThing	GDP-mannose biosynthetic process from fructose-6-phosphate	The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate.	got7fsn_ti							dph	2015-07-24T14:50:44Z				Reactome:R-HSA-446205		biological_process											owl:Class	
GO:0010224	biolink:NamedThing	response to UV-B	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.	got7fsn_ti	response to medium wave ultraviolet light stimulus|response to medium wave ultraviolet radiation stimulus|response to UVB radiation stimulus|response to UV-B radiation stimulus|response to UVB light stimulus|response to UV-B light stimulus													biological_process											owl:Class	
GO:0004365	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+.	got7fsn_ti	3-phosphoglyceraldehyde dehydrogenase activity|NAD-dependent glyceraldehyde phosphate dehydrogenase activity|glyceraldehyde phosphate dehydrogenase (NAD)|glyceraldehyde-3-P-dehydrogenase activity|phosphoglyceraldehyde dehydrogenase activity|GAPDH activity|triosephosphate dehydrogenase activity|NADH-glyceraldehyde phosphate dehydrogenase activity|dehydrogenase, glyceraldehyde phosphate|NAD-dependent glyceraldehyde-3-phosphate dehydrogenase activity|D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)											MetaCyc:GAPOXNPHOSPHN-RXN|Reactome:R-HSA-70482|EC:1.2.1.12|RHEA:10300|Reactome:R-HSA-70449		molecular_function											owl:Class	
GO:0090105	biolink:NamedThing	pancreatic E cell development	The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure.	got7fsn_ti							tb	2009-11-18T11:51:00Z						biological_process											owl:Class	
GO:0044395	biolink:NamedThing	protein targeting to vacuolar membrane	The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein.	got7fsn_ti							jl	2011-12-21T02:54:44Z						biological_process											owl:Class	
GO:0043892	biolink:NamedThing	methylglyoxal reductase (NADPH-dependent) activity	Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+.	got7fsn_ti	Gre2|lactaldehyde dehydrogenase (NADP+)|lactaldehyde:NADP+ oxidoreductase activity											RHEA:21748|EC:1.1.1.283|MetaCyc:RXN-8636|MetaCyc:1.1.1.283-RXN		molecular_function											owl:Class	
GO:0103020	biolink:NamedThing	1-deoxy-D-xylulose kinase activity	Catalysis of the reaction: 1-deoxy-D-xylulose + ATP <=> H+ + 1-deoxy-D-xylulose 5-phosphate + ADP.	got7fsn_ti												RHEA:27990|MetaCyc:RXN0-382		molecular_function											owl:Class	
GO:0019467	biolink:NamedThing	ornithine catabolic process, by decarboxylation	The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation.	got7fsn_ti	ornithine degradation, by decarboxylation|ornithine breakdown, by decarboxylation											MetaCyc:ORNDEG-PWY		biological_process											owl:Class	
GO:0006593	biolink:NamedThing	ornithine catabolic process	The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.	got7fsn_ti	ornithine catabolism|ornithine breakdown|ornithine degradation													biological_process											owl:Class	
GO:0047710	biolink:NamedThing	bis(5'-adenosyl)-triphosphatase activity	Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+).	got7fsn_ti	P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase activity|1-P,3-P-bis(5'-adenosyl)-triphosphate adenylohydrolase activity|dinucleosidetriphosphatase activity|AP(3)A hydrolase activity|AP3Aase activity|diadenosine 5,5-P1,P3-triphosphatase activity|AP3A hydrolase activity|diadenosine 5',5'''-P(1),P(3)-triphosphate hydrolase activity|diadenosine 5',5'''-P1,P3-triphosphate hydrolase activity|AP(3)Aase activity											RHEA:13893|KEGG_REACTION:R00187|MetaCyc:BIS5-ADENOSYL-TRIPHOSPHATASE-RXN|EC:3.6.1.29		molecular_function											owl:Class	
GO:0002926	biolink:NamedThing	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation	The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine.	got7fsn_ti	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis|mcm5 modification|mcm5s2U34 biosynthesis						hjd	2012-01-17T02:50:54Z						biological_process											owl:Class	
GO:0033150	biolink:NamedThing	cytoskeletal calyx	A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0033065	biolink:NamedThing	Rad51C-XRCC3 complex	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof.	got7fsn_ti	CX3 complex													cellular_component											owl:Class	
GO:0071908	biolink:NamedThing	determination of intestine left/right asymmetry	Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.	got7fsn_ti							mah	2010-09-22T10:24:33Z						biological_process											owl:Class	
GO:0031387	biolink:NamedThing	MPF complex	A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC).	got7fsn_ti														cellular_component											owl:Class	
GO:0046335	biolink:NamedThing	ethanolamine biosynthetic process	The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).	got7fsn_ti	ethanolamine synthesis|ethanolamine anabolism|ethanolamine formation|ethanolamine biosynthesis													biological_process											owl:Class	
GO:0001758	biolink:NamedThing	retinal dehydrogenase activity	Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.	got7fsn_ti	cytosolic retinal dehydrogenase activity|retinal:NAD+ oxidoreductase activity											MetaCyc:RETINAL-DEHYDROGENASE-RXN|RHEA:16177|Reactome:R-HSA-5362522|EC:1.2.1.36|Reactome:R-HSA-5696101		molecular_function											owl:Class	
GO:0036474	biolink:NamedThing	cell death in response to hydrogen peroxide	Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to hydrogen peroxide (H2O2).	got7fsn_ti	cell death in response to H2O2|hydrogen peroxide-mediated cell death				This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0010421 'hydrogen peroxide-mediated programmed cell death'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.		bf	2014-07-21T11:42:28Z						biological_process											owl:Class	
GO:0022809	biolink:NamedThing	mobile ion carrier activity	Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane.	got7fsn_ti	ionophore													molecular_function											owl:Class	
GO:0030713	biolink:NamedThing	ovarian follicle cell stalk formation	Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0102732	biolink:NamedThing	myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity	Catalysis of the reaction: 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ATP = H+ + myo-inositol hexakisphosphate(12-) + ADP.	got7fsn_ti												MetaCyc:RXN-7186|EC:2.7.1.140		molecular_function											owl:Class	
GO:0034819	biolink:NamedThing	3-HSA hydroxylase activity	Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.	got7fsn_ti												UM-BBD_reactionID:r1150|EC:1.14.13.-		molecular_function											owl:Class	
GO:0046581	biolink:NamedThing	intercellular canaliculus	An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates.	got7fsn_ti														cellular_component											owl:Class	
GO:0030953	biolink:NamedThing	astral microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.	got7fsn_ti	astral microtubule organisation|astral microtubule organization and biogenesis													biological_process											owl:Class	
GO:0033741	biolink:NamedThing	adenylyl-sulfate reductase (glutathione) activity	Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.	got7fsn_ti	plant-type 5'-adenylylsulfate reductase activity|AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming) activity|5'-adenylylsulfate reductase activity|AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming) activity											KEGG_REACTION:R05717|MetaCyc:1.8.4.9-RXN|EC:1.8.4.9|RHEA:14141		molecular_function											owl:Class	
GO:0070680	biolink:NamedThing	asparaginyl-tRNAAsn biosynthesis via transamidation	A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.	got7fsn_ti							mah	2009-06-02T03:11:19Z				MetaCyc:PWY490-4		biological_process											owl:Class	
GO:0004982	biolink:NamedThing	N-formyl peptide receptor activity	Combining with an N-formyl peptide to initiate a change in cell activity.	got7fsn_ti	Fmet-leu-phe receptor													molecular_function											owl:Class	
GO:0018054	biolink:NamedThing	peptidyl-lysine biotinylation	The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine.	got7fsn_ti												RESID:AA0117		biological_process											owl:Class	
GO:0033907	biolink:NamedThing	beta-D-fucosidase activity	Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides.	got7fsn_ti	beta-D-fucoside fucohydrolase activity|beta-fucosidase activity											EC:3.2.1.38|MetaCyc:3.2.1.38-RXN		molecular_function											owl:Class	
GO:0032287	biolink:NamedThing	peripheral nervous system myelin maintenance	The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.	got7fsn_ti	myelin maintenance in peripheral nervous system													biological_process											owl:Class	
GO:0044791	biolink:NamedThing	positive regulation by host of viral release from host cell	A process in which a host organism activates or increases the frequency, rate or extent of the release of a virus with which it is infected, from its cells.	got7fsn_ti							jl	2013-06-06T10:51:48Z						biological_process											owl:Class	
GO:0044794	biolink:NamedThing	positive regulation by host of viral process	A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected.	got7fsn_ti							jl	2013-06-06T11:33:51Z						biological_process											owl:Class	
GO:0044181	biolink:NamedThing	filamentous growth of a multicellular organism	The process in which a multicellular organism grows in a threadlike, filamentous shape.	got7fsn_ti							jl	2009-09-25T10:17:58Z						biological_process											owl:Class	
GO:0071176	biolink:NamedThing	MAML2-RBP-Jkappa-ICN2 complex	A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML2-RBP-Jkappa-Notch2 complex						mah	2009-11-23T02:42:24Z						cellular_component											owl:Class	
GO:0062131	biolink:NamedThing	3-butenylglucosinolate 2-hydroxylase activity	Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O.	got7fsn_ti	But-3-enyl Glucosinolate-2-hydroxylase activity						dph	2019-06-24T16:45:18Z				RHEA:60628|MetaCyc:RXNQT-4343		molecular_function											owl:Class	
GO:0061408	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to heat stress	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	got7fsn_ti							dph	2012-01-12T11:50:30Z						biological_process											owl:Class	
GO:0005539	biolink:NamedThing	glycosaminoglycan binding	Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.	got7fsn_ti														molecular_function											owl:Class	
GO:0061302	biolink:NamedThing	smooth muscle cell-matrix adhesion	The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.	got7fsn_ti							dph	2010-09-14T11:08:00Z						biological_process											owl:Class	
GO:0102518	biolink:NamedThing	(11Z)-eicosenoate 14-hydroxylase activity	Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-14488|EC:1.14.18.4		molecular_function											owl:Class	
GO:0033841	biolink:NamedThing	6G-fructosyltransferase activity	Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).	got7fsn_ti	fructan:fructan 6G-fructosyltransferase activity|6G-FT|6G-FFT|6G-fructotransferase activity|1F-oligo[beta-D-fructofuranosyl-(2->1)-]sucrose 6G-beta-D-fructotransferase activity											EC:2.4.1.243|MetaCyc:2.4.1.243-RXN		molecular_function											owl:Class	
GO:0034833	biolink:NamedThing	geranylate CoA-transferase activity	Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-.	got7fsn_ti												UM-BBD_reactionID:r1165		molecular_function											owl:Class	
GO:0002160	biolink:NamedThing	desmosome maintenance	The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.	got7fsn_ti					Desmosomes link two cells together; hemidesmosomes attach one cell to the extracellular matrix.		hjd	2010-02-09T10:50:59Z						biological_process											owl:Class	
GO:0051203	biolink:NamedThing	peptidyl-aspartic acid reduction to form L-aspartyl aldehyde	The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein.	got7fsn_ti	peptidyl-aspartic acid reduction to form L-aspartate-beta-semialdehyde|peptidyl-aspartic acid reduction to form L-beta-formylalanine				See also UniProtKB:P04160.							RESID:AA0373		biological_process											owl:Class	
GO:0051369	biolink:NamedThing	peptidyl-threonine decanoylation	The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.	got7fsn_ti												RESID:AA0387		biological_process											owl:Class	
GO:0061123	biolink:NamedThing	negative regulation of positive chemotaxis to cAMP	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.	got7fsn_ti							dph	2010-05-17T08:27:20Z						biological_process											owl:Class	
GO:1990250	biolink:NamedThing	transcription-coupled nucleotide-excision repair, DNA damage recognition complex	A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.	got7fsn_ti							bhm	2013-12-05T16:28:45Z						cellular_component											owl:Class	
GO:1990249	biolink:NamedThing	nucleotide-excision repair, DNA damage recognition complex	A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.	got7fsn_ti							bhm	2013-12-05T16:26:51Z						cellular_component											owl:Class	
GO:0050132	biolink:NamedThing	N-methylalanine dehydrogenase activity	Catalysis of the reaction: N-methyl-L-alanine + H(2)O + NADP(+) = H(+) + methylammonium + NADPH + pyruvate.	got7fsn_ti	N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating)											EC:1.4.1.17|RHEA:21768|MetaCyc:N-METHYLALANINE-DEHYDROGENASE-RXN|KEGG_REACTION:R01584		molecular_function											owl:Class	
GO:0036033	biolink:NamedThing	mediator complex binding	Binding to a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.	got7fsn_ti							bf	2011-10-31T05:09:12Z						molecular_function											owl:Class	
GO:0002565	biolink:NamedThing	somatic diversification of immune receptors via gene conversion	The process in which immune receptor genes are diversified through gene conversion.	got7fsn_ti														biological_process											owl:Class	
GO:0010410	biolink:NamedThing	hemicellulose metabolic process	The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present.	got7fsn_ti	hemicellulose metabolism													biological_process											owl:Class	
GO:0008073	biolink:NamedThing	ornithine decarboxylase inhibitor activity	Binds to and stops, prevents or reduces the activity of ornithine decarboxylase.	got7fsn_ti														molecular_function											owl:Class	
GO:0102610	biolink:NamedThing	(+)-secoisolariciresinol glucosyltransferase activity	Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol monoglucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-15442		molecular_function											owl:Class	
GO:0052544	biolink:NamedThing	defense response by callose deposition in cell wall	Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	got7fsn_ti	cell wall callose deposition during defense response|callose deposition in cell wall during defense response|cell wall callose localization during defense response|callose localization in cell wall during defense response													biological_process											owl:Class	
GO:0031712	biolink:NamedThing	B1 bradykinin receptor binding	Binding to a B1 bradykinin receptor.	got7fsn_ti	B1 bradykinin receptor ligand													molecular_function											owl:Class	
GO:0007232	biolink:NamedThing	osmosensory signaling pathway via Sho1 osmosensor	A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.	got7fsn_ti	osmosensory signalling pathway via Sho1 osmosensor|signal transduction during osmotic stress via Sho1 osmosensor													biological_process											owl:Class	
GO:0002206	biolink:NamedThing	gene conversion of immunoglobulin genes	The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion.	got7fsn_ti	gene conversion of antibody genes													biological_process											owl:Class	
GO:0050339	biolink:NamedThing	thymidine-triphosphatase activity	Catalysis of the reaction: dTTP + H2O = dTDP + phosphate.	got7fsn_ti	dTTP nucleotidohydrolase activity|dTTPase activity|thymidine triphosphate nucleotidohydrolase activity|deoxythymidine-5'-triphosphatase activity											EC:3.6.1.39|RHEA:19013|MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0015240	biolink:NamedThing	amiloride transmembrane transporter activity	Enables the transfer of amiloride from one side of a membrane to the other. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.	got7fsn_ti	amiloride transporter activity													molecular_function											owl:Class	
GO:0060225	biolink:NamedThing	positive regulation of retinal rod cell fate commitment	Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.	got7fsn_ti														biological_process											owl:Class	
GO:0033503	biolink:NamedThing	HULC complex	A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2.	got7fsn_ti														cellular_component											owl:Class	
GO:0039013	biolink:NamedThing	pronephric distal tubule morphogenesis	The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.	got7fsn_ti							bf	2010-07-02T09:58:03Z						biological_process											owl:Class	
GO:0001039	biolink:NamedThing	RNA polymerase III hybrid type promoter sequence-specific DNA binding	Binding to a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.	got7fsn_ti	RNA polymerase III hybrid type promoter DNA binding						krc	2010-08-23T06:21:24Z			GO:0001037			molecular_function											owl:Class	
GO:0008869	biolink:NamedThing	galactonate dehydratase activity	Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O.	got7fsn_ti	D-galactonate dehydrase activity|D-galactonate dehydratase activity|D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)|D-galactonate hydro-lyase activity											EC:4.2.1.6|MetaCyc:GALACTONDEHYDRAT-RXN|KEGG_REACTION:R03033|RHEA:18649		molecular_function											owl:Class	
GO:0097394	biolink:NamedThing	telomeric repeat-containing RNA transcription by RNA polymerase II	The synthesis of telomeric repeat-containing RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II promoter.	got7fsn_ti	telomeric RNA transcription from Pol II promoter|TERRA RNA transcription from RNA pol II promoter|telomeric repeat-containing RNA transcription from RNA pol II promoter	https://github.com/geneontology/go-ontology/issues/14854					pr	2012-10-23T10:09:15Z						biological_process											owl:Class	
GO:0061109	biolink:NamedThing	dense core granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.	got7fsn_ti	dense core granule organisation						dph	2010-05-01T09:34:37Z						biological_process											owl:Class	
GO:0010910	biolink:NamedThing	positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity	Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate.	got7fsn_ti														biological_process											owl:Class	
GO:0010912	biolink:NamedThing	positive regulation of isomerase activity	Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.	got7fsn_ti														biological_process											owl:Class	
GO:0030772	biolink:NamedThing	tryptophan 2-C-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+).	got7fsn_ti	tryptophan 2-methyltransferase activity|S-adenosylmethionine:tryptophan 2-methyltransferase activity|S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase activity											EC:2.1.1.106|KEGG_REACTION:R08547|MetaCyc:TRYPTOPHAN-2-C-METHYLTRANSFERASE-RXN|RHEA:17321		molecular_function											owl:Class	
GO:0080044	biolink:NamedThing	quercetin 7-O-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0046655	biolink:NamedThing	folic acid metabolic process	The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.	got7fsn_ti	vitamin M metabolic process|folate metabolic process|vitamin B9 metabolic process|folate metabolism|vitamin M metabolism|vitamin B9 metabolism|folic acid metabolism													biological_process											owl:Class	
GO:0030796	biolink:NamedThing	cycloartenol 24-C-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase activity|sterol C-methyltransferase activity											MetaCyc:2.1.1.142-RXN|EC:2.1.1.142|RHEA:13137|KEGG_REACTION:R05760		molecular_function											owl:Class	
GO:0035937	biolink:NamedThing	estrogen secretion	The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals.	got7fsn_ti	oestrogen secretion						bf	2011-07-20T01:14:44Z						biological_process											owl:Class	
GO:0008763	biolink:NamedThing	UDP-N-acetylmuramate-L-alanine ligase activity	Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine.	got7fsn_ti	MurC synthetase activity|uridine diphospho-N-acetylmuramoylalanine synthetase activity|UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)|alanine-adding enzyme activity|UDP-N-acetylmuramoylalanine synthetase activity|UDPMurNAc-L-alanine synthetase activity|UDP-N-acetylmuramoyl-L-alanine synthetase activity|L-alanine-adding enzyme activity|L-Ala ligase activity|UDP-MurNAc:L-alanine ligase activity|UDP-acetylmuramyl-L-alanine synthetase activity|uridine diphosphate N-acetylmuramate:L-alanine ligase activity|uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity|UDP-N-acetylmuramyl:L-alanine ligase activity|uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity											RHEA:23372|MetaCyc:UDP-NACMUR-ALA-LIG-RXN|EC:6.3.2.8|KEGG_REACTION:R03193		molecular_function											owl:Class	
GO:0086029	biolink:NamedThing	Purkinje myocyte to ventricular cardiac muscle cell signaling	Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell.	got7fsn_ti	Purkinje myocyte to ventricular cardiac muscle cell signalling						tb	2011-11-11T02:02:14Z						biological_process											owl:Class	
GO:0019084	biolink:NamedThing	middle viral transcription	The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication.	got7fsn_ti	(delayed) early viral mRNA transcription													biological_process											owl:Class	
GO:0010025	biolink:NamedThing	wax biosynthetic process	The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids.	got7fsn_ti	wax biosynthesis|wax synthesis|wax formation|wax anabolism											MetaCyc:PWY-282		biological_process											owl:Class	
GO:0031474	biolink:NamedThing	myosin IV complex	A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.	got7fsn_ti														cellular_component											owl:Class	
GO:0018238	biolink:NamedThing	peptidyl-lysine carboxyethylation	The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.	got7fsn_ti	protein amino acid carboxyethylation										GO:0018239	RESID:AA0115		biological_process											owl:Class	
GO:0004923	biolink:NamedThing	leukemia inhibitory factor receptor activity	Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	LIF receptor activity|leukemia inhibitory factor receptor beta-protein activity										GO:0004899			molecular_function											owl:Class	
GO:0008941	biolink:NamedThing	nitric oxide dioxygenase activity	Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+.	got7fsn_ti	NOD activity|nitric oxide,NAD(P)H:oxygen oxidoreductase activity											MetaCyc:R621-RXN|EC:1.14.12.17|Reactome:R-HSA-5340226|Reactome:R-HSA-1222723		molecular_function											owl:Class	
GO:0001117	biolink:NamedThing	protein-DNA-RNA complex disassembly	The disaggregation of a protein-DNA-RNA complex into its constituent components.	got7fsn_ti							krc	2010-12-03T04:04:07Z						biological_process											owl:Class	
GO:0050252	biolink:NamedThing	retinol O-fatty-acyltransferase activity	Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester.	got7fsn_ti	acyl-CoA:retinol O-acyltransferase activity|retinol fatty-acyltransferase activity|retinol acyltransferase activity											EC:2.3.1.76|MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN|Reactome:R-HSA-8848585|Reactome:R-HSA-2465919|RHEA:11488		molecular_function											owl:Class	
GO:0018768	biolink:NamedThing	2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate.	got7fsn_ti												UM-BBD_reactionID:r0458|EC:3.7.1.13		molecular_function											owl:Class	
GO:0072687	biolink:NamedThing	meiotic spindle	A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.	got7fsn_ti							mah	2011-07-08T05:17:08Z						cellular_component											owl:Class	
GO:0055064	biolink:NamedThing	chloride ion homeostasis	Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0000343	biolink:NamedThing	plastid-encoded plastid RNA polymerase complex A	A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex.	got7fsn_ti	PEP-A													cellular_component											owl:Class	
GO:0000427	biolink:NamedThing	plastid-encoded plastid RNA polymerase complex	An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition.	got7fsn_ti														cellular_component											owl:Class	
GO:0102041	biolink:NamedThing	7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase	Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid.	got7fsn_ti												EC:2.5.1.105|MetaCyc:RXN-10009|RHEA:35951		molecular_function											owl:Class	
GO:0050072	biolink:NamedThing	m7G(5')pppN diphosphatase activity	Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide.	got7fsn_ti	M(7)G(5')pppN pyrophosphatase activity|m7G(5')pppN pyrophosphatase activity|decapase activity|7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity											EC:3.6.1.30|MetaCyc:M7G5PPPN-PYROPHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0010242	biolink:NamedThing	oxygen evolving activity	Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.	got7fsn_ti	photosynthetic water oxidation											RHEA:36359|MetaCyc:RXN0-5265|EC:1.10.3.9|MetaCyc:PSII-RXN		molecular_function											owl:Class	
GO:0008295	biolink:NamedThing	spermidine biosynthetic process	The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	got7fsn_ti	spermidine biosynthesis|spermidine formation|spermidine synthesis|spermidine anabolism											MetaCyc:BSUBPOLYAMSYN-PWY|MetaCyc:POLYAMINSYN3-PWY		biological_process											owl:Class	
GO:0021817	biolink:NamedThing	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration.	got7fsn_ti	nucleokinesis involved in cell locomotion in cerebral cortex radial glia guided migration|nucleokinesis involved in cell locomotion in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0098672	biolink:NamedThing	evasion by virus of CRISPR-cas system	Any process, either active or passive, by which a virus evades the CRISPR-cas system of its host. Some viruses can directly suppress the CRISPR system.	got7fsn_ti	CRISPR-cas system evasion by virus						dos	2017-01-16T13:38:27Z				VZ:3962		biological_process											owl:Class	
GO:0061483	biolink:NamedThing	sulfinylpropanyl adenylate synthase	Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate.	got7fsn_ti	SPA synthase						dph	2012-11-16T10:08:15Z						molecular_function											owl:Class	
GO:0004512	biolink:NamedThing	inositol-3-phosphate synthase activity	Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.	got7fsn_ti	1L-myo-inositol-1-phosphate lyase (isomerizing)|glucose 6-phosphate cyclase activity|D-glucose 6-phosphate cycloaldolase activity|inositol 1-phosphate synthetase activity|glucose-6-phosphate inositol monophosphate cycloaldolase activity|glucocycloaldolase activity|inositol 1-phosphate synthatase activity											Reactome:R-HSA-1855178|EC:5.5.1.4|MetaCyc:MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN|KEGG_REACTION:R07324|RHEA:10716		molecular_function											owl:Class	
GO:0047749	biolink:NamedThing	cholestanetriol 26-monooxygenase activity	Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O.	got7fsn_ti	cholesterol 27-hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase activity|cytochrome P450 27A1' activity|CYP27A|sterol 27-hydroxylase activity|cholestanetriol 26-hydroxylase activity|sterol 26-hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase activity|CYP27A1|5beta-cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase activity|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase activity											MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN|RHEA:14373|EC:1.14.15.15		molecular_function											owl:Class	
GO:0051554	biolink:NamedThing	flavonol metabolic process	The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.	got7fsn_ti	flavonol metabolism													biological_process											owl:Class	
GO:0035254	biolink:NamedThing	glutamate receptor binding	Binding to a glutamate receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0034556	biolink:NamedThing	nitrobenzoate nitroreductase activity	Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+.	got7fsn_ti												EC:1.7.1.-|UM-BBD_reactionID:r0849		molecular_function											owl:Class	
GO:0052724	biolink:NamedThing	inositol hexakisphosphate 3-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.	got7fsn_ti							ai	2011-08-16T11:50:48Z				EC:2.7.4.21|MetaCyc:RXN-10971		molecular_function											owl:Class	
GO:0000439	biolink:NamedThing	transcription factor TFIIH core complex	The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.	got7fsn_ti	core TFIIH complex|SSL2-core TFIIH complex										GO:0000441			cellular_component											owl:Class	
GO:0052668	biolink:NamedThing	CTP:farnesol kinase activity	Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+.	got7fsn_ti	CTP:2-trans,-6-trans-farnesol kinase activity|CTP:2-trans,-6-trans-farnesol phosphotransferase activity|farnesol phosphotransferase activity|trans,trans-farnesol kinase activity|farnesol kinase activity	https://github.com/geneontology/go-ontology/issues/21619					ai	2011-04-11T01:19:25Z			GO:0052669	EC:2.7.1.216|RHEA:51680|MetaCyc:RXN-11625		molecular_function											owl:Class	
GO:0060111	biolink:NamedThing	alae of collagen and cuticulin-based cuticle extracellular matrix	Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively.	got7fsn_ti	alae of collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0005111	biolink:NamedThing	type 2 fibroblast growth factor receptor binding	Binding to a type 2 fibroblast growth factor receptor (FGFR2).	got7fsn_ti	heartless binding|type 2 fibroblast growth factor receptor ligand|heartless ligand|FGFR2 ligand|FGFR2 binding				Note that heartless is the Drosophila gene encoding the type 2 fibroblast growth factor receptor (FGFR2).									molecular_function											owl:Class	
GO:0031701	biolink:NamedThing	angiotensin receptor binding	Binding to an angiotensin receptor.	got7fsn_ti	angiotensin receptor ligand													molecular_function											owl:Class	
GO:0071481	biolink:NamedThing	cellular response to X-ray	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).	got7fsn_ti	cellular response to X-ray radiation stimulus						mah	2009-12-18T02:00:59Z						biological_process											owl:Class	
GO:0010165	biolink:NamedThing	response to X-ray	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).	got7fsn_ti	response to X-ray radiation stimulus													biological_process											owl:Class	
GO:1990387	biolink:NamedThing	isogloboside biosynthetic process	The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides).	got7fsn_ti							hjd	2014-05-30T17:36:51Z						biological_process											owl:Class	
GO:0006688	biolink:NamedThing	glycosphingolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.	got7fsn_ti	glycosphingolipid biosynthesis|glycosphingolipid formation|glycosphingolipid synthesis|glycosphingolipid anabolism													biological_process											owl:Class	
GO:0050351	biolink:NamedThing	trimetaphosphatase activity	Catalysis of the reaction: H(2)O + trimetaphosphate = 2 H(+) + triphosphate.	got7fsn_ti	trimetaphosphate hydrolase activity|inorganic trimetaphosphatase activity											KEGG_REACTION:R02504|RHEA:11088|EC:3.6.1.2|MetaCyc:TRIMETAPHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0046694	biolink:NamedThing	sperm incapacitation	The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males.	got7fsn_ti														biological_process											owl:Class	
GO:0034092	biolink:NamedThing	negative regulation of maintenance of sister chromatid cohesion	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.	got7fsn_ti														biological_process											owl:Class	
GO:0042545	biolink:NamedThing	cell wall modification	The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly.	got7fsn_ti														biological_process											owl:Class	
GO:0004582	biolink:NamedThing	dolichyl-phosphate beta-D-mannosyltransferase activity	Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.	got7fsn_ti	mannosylphosphodolichol synthase activity|GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase activity|dolichol-phosphate mannose synthase activity|dolichyl-phosphate mannose synthase activity|GDPmannose:dolichyl-phosphate mannosyltransferase activity|GDP-mannose-dolichol phosphate mannosyltransferase activity|dolichol-phosphate-mannose synthase activity|guanosine diphosphomannose-dolichol phosphate mannosyltransferase activity|GDPmannose-dolichylmonophosphate mannosyltransferase activity|dolichyl phosphate mannosyltransferase activity|dolichol phosphate mannose synthase activity|dolichol-phosphate mannosyltransferase activity|mannosylphosphoryldolichol synthase activity|DPM synthase activity|dolichyl-phospho-mannose synthase activity|dolichyl mannosyl phosphate synthase activity|GDPMan:DolP mannosyltransferase activity											Reactome:R-HSA-162721|Reactome:R-HSA-4719354|Reactome:R-HSA-4719375|RHEA:21184|EC:2.4.1.83|MetaCyc:2.4.1.83-RXN|Reactome:R-HSA-4717406		molecular_function											owl:Class	
GO:0045702	biolink:NamedThing	positive regulation of spermatid nuclear differentiation	Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.	got7fsn_ti	stimulation of spermatid nuclear differentiation|upregulation of spermatid nuclear differentiation|up-regulation of spermatid nuclear differentiation|up regulation of spermatid nuclear differentiation|activation of spermatid nuclear differentiation													biological_process											owl:Class	
GO:0098785	biolink:NamedThing	biofilm matrix assembly	A process that results in the assembly of a biofilm matrix.	got7fsn_ti														biological_process											owl:Class	
GO:0052925	biolink:NamedThing	dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity	Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.	got7fsn_ti	man(5)GlcNAc(2)-PP-Dol mannosyltransferase activity|dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase activity											RHEA:29527|EC:2.4.1.258|KEGG_REACTION:R06258|MetaCyc:RXN-5466		molecular_function											owl:Class	
GO:0000033	biolink:NamedThing	alpha-1,3-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.	got7fsn_ti												Reactome:R-HSA-4549368|Reactome:R-HSA-4720473|Reactome:R-HSA-446208|Reactome:R-HSA-446188		molecular_function											owl:Class	
GO:0047778	biolink:NamedThing	[citrate-(pro-3S)-lyase] thiolesterase activity	Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate.	got7fsn_ti	citrate-(pro-3S)-lyase thioesterase activity|[citrate-(pro-3S)-lyase] thioesterase activity|citrate lyase deacetylase activity|citrate-(pro-3S)-lyase(acetyl-form) hydrolase activity|citrate-(pro-3S)-lyase thiolesterase activity|citrate (pro-3S)-lyase thiolesterase activity											MetaCyc:CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN|EC:3.1.2.16|RHEA:13657		molecular_function											owl:Class	
GO:0090112	biolink:NamedThing	COPII vesicle uncoating	The process in which COPII vesicle coat proteins are disassembled, and released.	got7fsn_ti							tb	2009-12-06T08:56:50Z						biological_process											owl:Class	
GO:0035848	biolink:NamedThing	oviduct morphogenesis	The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.	got7fsn_ti	fallopian tube morphogenesis						bf	2011-05-10T11:01:20Z						biological_process											owl:Class	
GO:0003215	biolink:NamedThing	cardiac right ventricle morphogenesis	The process in which the right cardiac ventricle is generated and organized.	got7fsn_ti							dph	2009-10-13T09:50:57Z						biological_process											owl:Class	
GO:0097661	biolink:NamedThing	SCF-Ctf13 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae.	got7fsn_ti							pr	2014-10-06T10:25:56Z						cellular_component											owl:Class	
GO:0016231	biolink:NamedThing	beta-N-acetylglucosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.	got7fsn_ti														molecular_function											owl:Class	
GO:0050613	biolink:NamedThing	delta14-sterol reductase activity	Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.	got7fsn_ti	sterol C14-reductase activity|D14-sterol reductase activity|C-14 sterol reductase activity|4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity|sterol C-14 reductase activity				Note that zymosterol is cholesta-8,24-dien-3-ol.						GO:0000251	Reactome:R-HSA-194674|EC:1.3.1.70|RHEA:18561|MetaCyc:1.3.1.70-RXN|Reactome:R-HSA-194698		molecular_function											owl:Class	
GO:0042652	biolink:NamedThing	mitochondrial respiratory chain complex I, peripheral segment	The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.	got7fsn_ti	NADH-Q oxidoreductase complex, peripheral segment|NADH dehydrogenase (ubiquinone) complex, peripheral segment													cellular_component											owl:Class	
GO:1990853	biolink:NamedThing	histone H2A SQE motif phosphorylation	The modification of histone H2A by the addition of an phosphate group to the serine residue in the SQE motif of the histone.	got7fsn_ti							al	2015-09-15T15:18:02Z						biological_process											owl:Class	
GO:0010435	biolink:NamedThing	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity	Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0.	got7fsn_ti	3-oxo-2-(2'-[Z]-pentenyl)cyclopentane-1-octanoate CoA ligase activity|OPC-8:0 CoA ligase activity|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity											EC:6.2.1.-|MetaCyc:RXN-10695		molecular_function											owl:Class	
GO:0001920	biolink:NamedThing	negative regulation of receptor recycling	Any process that stops, prevents, or reduces the rate of receptor recycling.	got7fsn_ti	downregulation of receptor recycling|down-regulation of receptor recycling|down regulation of receptor recycling|inhibition of receptor recycling													biological_process											owl:Class	
GO:0060719	biolink:NamedThing	chorionic trophoblast cell development	The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	got7fsn_ti							dph	2009-06-11T02:58:45Z						biological_process											owl:Class	
GO:0047213	biolink:NamedThing	anthocyanidin 3-O-glucosyltransferase activity	Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP.	got7fsn_ti	uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase activity|UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-glucosyltransferase activity|UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase activity|3-GT activity|UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase activity											MetaCyc:2.4.1.115-RXN|RHEA:20093|EC:2.4.1.115		molecular_function											owl:Class	
GO:0140685	biolink:NamedThing	histone H3-di/monomethyl-lysine-9 FAD-dependent demethylase activity	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.	got7fsn_ti	histone H3K9me demethylase activity|histone H3K9me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089					pg	2021-07-09T07:18:00Z						molecular_function											owl:Class	
GO:0046577	biolink:NamedThing	long-chain-alcohol oxidase activity	Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.	got7fsn_ti	fatty alcohol oxidase activity|long-chain-alcohol:oxygen oxidoreductase activity|fatty alcohol:oxygen oxidoreductase activity|long-chain fatty acid oxidase activity|long-chain fatty alcohol oxidase activity											EC:1.1.3.20|MetaCyc:LONG-CHAIN-ALCOHOL-OXIDASE-RXN|RHEA:22756		molecular_function											owl:Class	
GO:0018400	biolink:NamedThing	peptidyl-proline hydroxylation to 3-hydroxy-L-proline	The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase.	got7fsn_ti					See also the molecular function term 'procollagen-proline 3-dioxygenase activity ; GO:0019797'.							RESID:AA0029		biological_process											owl:Class	
GO:0002052	biolink:NamedThing	positive regulation of neuroblast proliferation	Any process that activates or increases the rate of neuroblast proliferation.	got7fsn_ti	stimulation of neuroblast proliferation|up-regulation of neuroblast proliferation|up regulation of neuroblast proliferation|upregulation of neuroblast proliferation|activation of neuroblast proliferation													biological_process											owl:Class	
GO:0043023	biolink:NamedThing	ribosomal large subunit binding	Binding to a large ribosomal subunit.	got7fsn_ti														molecular_function											owl:Class	
GO:0039696	biolink:NamedThing	RNA-templated viral transcription	A transcription process that uses viral RNA as a template.	got7fsn_ti							bf	2013-10-28T13:28:01Z						biological_process											owl:Class	
GO:0045103	biolink:NamedThing	intermediate filament-based process	Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.	got7fsn_ti														biological_process											owl:Class	
GO:1990683	biolink:NamedThing	DNA double-strand break attachment to nuclear envelope	A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs.	got7fsn_ti							vw	2015-03-10T16:36:21Z						biological_process											owl:Class	
GO:0051880	biolink:NamedThing	G-quadruplex DNA binding	Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.	got7fsn_ti	G-DNA binding|G quartet binding|G-quartet DNA binding|G quartet DNA binding|tetraplex DNA binding|G-quartet binding|G quadruplex DNA binding|quadruplex DNA binding													molecular_function											owl:Class	
GO:0000937	biolink:NamedThing	dolipore septum	A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome).	got7fsn_ti														cellular_component											owl:Class	
GO:0000934	biolink:NamedThing	porous cell septum	A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments.	got7fsn_ti	porous septum													cellular_component											owl:Class	
GO:0018312	biolink:NamedThing	peptidyl-serine ADP-ribosylation	The transfer, from NAD, of ADP-ribose to peptidyl-serine to form peptidyl-O-(ADP-ribosyl)-L-serine.	got7fsn_ti												RESID:AA0237		biological_process											owl:Class	
GO:0030093	biolink:NamedThing	chloroplast photosystem I	Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana.	got7fsn_ti														cellular_component											owl:Class	
GO:0061902	biolink:NamedThing	negative regulation of 1-phosphatidylinositol-3-kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity.	got7fsn_ti							dph	2017-06-22T19:51:34Z						biological_process											owl:Class	
GO:0006661	biolink:NamedThing	phosphatidylinositol biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.	got7fsn_ti	phosphatidylinositol anabolism|PtdIns biosynthesis|phosphatidylinositol biosynthesis|PtdIns biosynthetic process|phosphoinositide biosynthesis|phosphatidylinositol synthesis|phosphoinositide biosynthetic process|phosphatidylinositol formation										GO:0046489			biological_process											owl:Class	
GO:0019813	biolink:NamedThing	type III site-specific deoxyribonuclease complex	A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.	got7fsn_ti	type III restriction enzyme complex													cellular_component											owl:Class	
NCBITaxon:32524	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035240	biolink:NamedThing	dopamine binding	Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.	got7fsn_ti														molecular_function											owl:Class	
GO:1905788	biolink:NamedThing	negative regulation of detection of mechanical stimulus involved in sensory perception of touch	Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.	got7fsn_ti	down regulation of perception of touch, sensory detection of mechanical stimulus|down-regulation of perception of touch, sensory transduction of mechanical stimulus|downregulation of detection of mechanical stimulus involved in sensory perception of touch|downregulation of perception of touch, sensory transduction of mechanical stimulus|inhibition of tactition, sensory detection of mechanical stimulus|downregulation of sensory detection of mechanical stimulus during perception of touch|down regulation of tactition, sensory detection of mechanical stimulus|negative regulation of sensory transduction of mechanical stimulus during perception of touch|downregulation of perception of touch, detection of mechanical stimulus|inhibition of detection of mechanical stimulus involved in sensory perception of touch|negative regulation of sensory detection of mechanical stimulus during perception of touch|inhibition of perception of touch, sensory detection of mechanical stimulus|down-regulation of sensory detection of mechanical stimulus during perception of touch|negative regulation of perception of touch, detection of mechanical stimulus|inhibition of sensory detection of mechanical stimulus during perception of touch|inhibition of perception of touch, detection of mechanical stimulus|down regulation of perception of touch, detection of mechanical stimulus|downregulation of perception of touch, sensory detection of mechanical stimulus|down-regulation of perception of touch, detection of mechanical stimulus|down regulation of perception of touch, sensory transduction of mechanical stimulus|down-regulation of tactition, sensory detection of mechanical stimulus|negative regulation of tactition, sensory detection of mechanical stimulus|negative regulation of perception of touch, sensory transduction of mechanical stimulus|down regulation of sensory detection of mechanical stimulus during perception of touch|down regulation of detection of mechanical stimulus involved in sensory perception of touch|down-regulation of perception of touch, sensory detection of mechanical stimulus|down-regulation of sensory transduction of mechanical stimulus during perception of touch|downregulation of tactition, sensory detection of mechanical stimulus|down regulation of sensory transduction of mechanical stimulus during perception of touch|inhibition of sensory transduction of mechanical stimulus during perception of touch|down-regulation of detection of mechanical stimulus involved in sensory perception of touch|downregulation of sensory transduction of mechanical stimulus during perception of touch|negative regulation of perception of touch, sensory detection of mechanical stimulus|inhibition of perception of touch, sensory transduction of mechanical stimulus						hbye	2017-01-09T15:11:14Z						biological_process											owl:Class	
GO:0009788	biolink:NamedThing	negative regulation of abscisic acid-activated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.	got7fsn_ti	inhibition of abscisic acid mediated signaling|down-regulation of abscisic acid mediated signaling|negative regulation of abscisic acid mediated signalling|negative regulation of abscisic acid mediated signaling pathway|down regulation of abscisic acid mediated signaling|downregulation of abscisic acid mediated signaling													biological_process											owl:Class	
GO:1905909	biolink:NamedThing	regulation of dauer entry	Any process that modulates the frequency, rate or extent of dauer entry.	got7fsn_ti	regulation of nematode entry into dormancy						hbye	2017-02-06T15:34:01Z						biological_process											owl:Class	
GO:1904655	biolink:NamedThing	positive regulation of lung alveolus development	Any process that activates or increases the frequency, rate or extent of lung alveolus development.	got7fsn_ti	positive regulation of alveolarization|upregulation of alveolarization|up-regulation of alveolarization|up regulation of alveolarization|up-regulation of lung alveolus development|up regulation of alveologenesis|up regulation of lung alveolus development|activation of lung alveolus development|activation of alveologenesis|upregulation of lung alveolus development|activation of alveolarization|up-regulation of alveologenesis|upregulation of alveologenesis|positive regulation of alveologenesis						sl	2015-09-03T22:44:56Z						biological_process											owl:Class	
GO:1901474	biolink:NamedThing	azole transmembrane transporter activity	Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other.	got7fsn_ti	azole transporter activity						tb	2012-10-04T20:00:27Z			GO:0045118			molecular_function											owl:Class	
GO:0045117	biolink:NamedThing	azole transmembrane transport	The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane.	got7fsn_ti	azole transport													biological_process											owl:Class	
GO:0061267	biolink:NamedThing	mesonephric interstitial fibroblast development	The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.	got7fsn_ti	mesonephros interstitial cell development						dph	2010-08-30T03:14:31Z						biological_process											owl:Class	
GO:1903904	biolink:NamedThing	negative regulation of establishment of T cell polarity	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.	got7fsn_ti	downregulation of T-cell polarization|downregulation of T lymphocyte polarization|inhibition of T-cell polarization|inhibition of establishment of T-lymphocyte polarity|downregulation of establishment of T-lymphocyte polarity|downregulation of T cell polarization|negative regulation of T cell polarization|down regulation of establishment of T-cell polarity|down-regulation of establishment of T-cell polarity|down-regulation of T-cell polarization|negative regulation of T-cell polarization|negative regulation of T lymphocyte polarization|down-regulation of establishment of T-lymphocyte polarity|down regulation of establishment of T lymphocyte polarity|down regulation of establishment of T cell polarity|downregulation of establishment of T lymphocyte polarity|negative regulation of establishment of T lymphocyte polarity|down regulation of T cell polarization|inhibition of establishment of T-cell polarity|down regulation of T lymphocyte polarization|downregulation of establishment of T cell polarity|inhibition of T lymphocyte polarization|down regulation of T-cell polarization|down-regulation of establishment of T cell polarity|inhibition of T cell polarization|down regulation of establishment of T-lymphocyte polarity|negative regulation of establishment of T-cell polarity|down-regulation of T lymphocyte polarization|down-regulation of T cell polarization|downregulation of establishment of T-cell polarity|inhibition of establishment of T cell polarity|inhibition of establishment of T lymphocyte polarity|down-regulation of establishment of T lymphocyte polarity|negative regulation of establishment of T-lymphocyte polarity						als	2015-02-09T10:50:30Z						biological_process											owl:Class	
SO:0000275	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0021860	biolink:NamedThing	pyramidal neuron development	The progression of a pyramidal neuron from its initial formation to its mature state.	got7fsn_ti	projection neuron development													biological_process											owl:Class	
GO:0044691	biolink:NamedThing	tooth eruption	The tooth development process in which the teeth enter the mouth and become visible.	got7fsn_ti							jl	2012-08-15T14:58:17Z				Wikipedia:Tooth_eruption		biological_process											owl:Class	
GO:0035849	biolink:NamedThing	nephric duct elongation	The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney.	got7fsn_ti							bf	2011-05-11T11:31:39Z						biological_process											owl:Class	
GO:0061449	biolink:NamedThing	olfactory bulb tufted cell development	The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti							dph	2012-05-15T12:30:21Z						biological_process											owl:Class	
GO:0099502	biolink:NamedThing	calcium-dependent activation of synaptic vesicle fusion	The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0003324	biolink:NamedThing	pancreatic D cell development	The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.	got7fsn_ti	pancreatic delta cell development						dph	2009-11-02T08:23:26Z						biological_process											owl:Class	
GO:0071068	biolink:NamedThing	alpha9-beta1 integrin-ADAM12 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.	got7fsn_ti	ITGA9-ITGB1-ADAM12 complex						mah	2009-11-03T04:05:15Z						cellular_component											owl:Class	
GO:0015653	biolink:NamedThing	glycine betaine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in).	got7fsn_ti	glycine betaine:hydrogen symporter activity													molecular_function											owl:Class	
GO:0031460	biolink:NamedThing	glycine betaine transport	The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	N-trimethylglycine transport													biological_process											owl:Class	
GO:0014004	biolink:NamedThing	microglia differentiation	The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.	got7fsn_ti	microglial cell differentiation													biological_process											owl:Class	
GO:0021921	biolink:NamedThing	regulation of cell proliferation in dorsal spinal cord	The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord.	got7fsn_ti														biological_process											owl:Class	
GO:0009343	biolink:NamedThing	biotin carboxylase complex	An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2).	got7fsn_ti														cellular_component											owl:Class	
GO:0043598	biolink:NamedThing	cytoplasmic DNA replication factor C complex	A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. Examples of this component are found in prokaryotic species.	got7fsn_ti	cytoplasmic RFC|cytoplasmic clamp loader													cellular_component											owl:Class	
GO:1904512	biolink:NamedThing	regulation of initiation of premeiotic DNA replication	Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication.	got7fsn_ti	regulation of premeiotic DNA replication initiation|regulation of initiation of meiotic DNA synthesis|regulation of meiotic DNA replication initiation|regulation of initiation of premeiotic DNA synthesis						mah	2015-07-28T12:59:17Z						biological_process											owl:Class	
GO:0048142	biolink:NamedThing	germarium-derived cystoblast division	The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	germarium-derived cystoblast cell division													biological_process											owl:Class	
GO:0061400	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to calcium ion	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a calcium ion stimulus.	got7fsn_ti							dph	2012-01-10T09:36:02Z						biological_process											owl:Class	
GO:0071277	biolink:NamedThing	cellular response to calcium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.	got7fsn_ti	cellular response to Ca2+ ion						mah	2009-12-10T03:55:01Z						biological_process											owl:Class	
GO:1903952	biolink:NamedThing	regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.	got7fsn_ti	regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization						nc	2015-02-24T10:32:06Z						biological_process											owl:Class	
GO:0086013	biolink:NamedThing	membrane repolarization during cardiac muscle cell action potential	The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	got7fsn_ti							tb	2011-11-10T08:23:25Z						biological_process											owl:Class	
GO:0072305	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.	got7fsn_ti	negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis						mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:1905422	biolink:NamedThing	negative regulation of plant organ morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis.	got7fsn_ti	down regulation of plant organ morphogenesis|down-regulation of plant organ morphogenesis|inhibition of plant organ morphogenesis|downregulation of plant organ morphogenesis						tb	2016-09-06T23:00:22Z						biological_process											owl:Class	
GO:0010127	biolink:NamedThing	mycothiol-dependent detoxification	The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.	got7fsn_ti	mycothiol-dependent detoxification of alkylating agent											MetaCyc:PWY1G-170|MetaCyc:PWY1G-1		biological_process											owl:Class	
GO:0061004	biolink:NamedThing	pattern specification involved in kidney development	Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.	got7fsn_ti	pattern formation involved in kidney development|kidney pattern formation|kidney pattern specification						dph	2010-01-21T09:05:54Z						biological_process											owl:Class	
GO:0015200	biolink:NamedThing	methylammonium transmembrane transporter activity	Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0072489	biolink:NamedThing	methylammonium transmembrane transport	The process in which methylammonium is transported across a membrane.	got7fsn_ti	methylammonium membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-12-10T10:36:33Z						biological_process											owl:Class	
GO:1905350	biolink:NamedThing	Y-shaped link assembly	The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate.	got7fsn_ti	membrane-microtubule complex formation|Y-shaped fibre assembly|Y-shaped linker assembly|Y-link assembly|Y-shaped link formation|Y-shaped fiber formation|membrane-microtubule complex assembly|Y-shaped fibre formation|Y-link structure assembly|Y-shaped assemblage assembly|Y-shaped linker formation|Y-link formation|Y-shaped assemblage formation|Y-shaped fiber assembly|Y-link structure formation						pr	2016-08-04T16:04:26Z						biological_process											owl:Class	
GO:1903205	biolink:NamedThing	regulation of hydrogen peroxide-induced cell death	Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced cell death.	got7fsn_ti	regulation of cell death in response to H2O2|protection against hydrogen peroxide-mediated cell death|regulation of cell death in response to hydrogen peroxide|regulation of hydrogen peroxide-mediated cell death						bf	2014-07-21T16:21:47Z						biological_process											owl:Class	
GO:0035277	biolink:NamedThing	spiracle morphogenesis, open tracheal system	The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk.	got7fsn_ti	spiracle morphogenesis													biological_process											owl:Class	
GO:0003323	biolink:NamedThing	type B pancreatic cell development	The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.	got7fsn_ti	pancreatic B cell development|pancreatic beta cell development						dph	2009-11-02T08:20:11Z						biological_process											owl:Class	
GO:0003309	biolink:NamedThing	type B pancreatic cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.	got7fsn_ti	pancreatic B cell differentiation|pancreatic beta cell differentiation						dph	2009-10-26T09:27:23Z						biological_process											owl:Class	
GO:0015130	biolink:NamedThing	mevalonate transmembrane transporter activity	Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds.	got7fsn_ti	monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity													molecular_function											owl:Class	
GO:0015728	biolink:NamedThing	mevalonate transport	The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1905757	biolink:NamedThing	negative regulation of primary cell septum biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis.	got7fsn_ti							vw	2016-12-12T18:09:59Z						biological_process											owl:Class	
GO:0080153	biolink:NamedThing	negative regulation of reductive pentose-phosphate cycle	Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle.	got7fsn_ti	negative regulation of C3 photosynthesis|negative regulation of Calvin cycle						dhl	2010-07-01T02:55:27Z						biological_process											owl:Class	
GO:0014860	biolink:NamedThing	neurotransmitter secretion involved in regulation of skeletal muscle contraction	The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.	got7fsn_ti	neurotransmitter secretion involved in control of skeletal muscle contraction													biological_process											owl:Class	
GO:0072108	biolink:NamedThing	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.	got7fsn_ti							mah	2010-02-12T02:45:57Z						biological_process											owl:Class	
UBERON:0000160	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002914	biolink:NamedThing	regulation of central B cell anergy	Any process that modulates the frequency, rate, or extent of central B cell anergy.	got7fsn_ti														biological_process											owl:Class	
GO:0097728	biolink:NamedThing	9+0 motile cilium	A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).	got7fsn_ti	motile 9+0 cilium|nodal cilium				This type of cilia may be present in solitary (classic nodal cilia in embryonic nodes) or in multiple copies (e.g. in the choroid plexus epithelium).		pr	2016-09-27T15:24:37Z						cellular_component											owl:Class	
GO:0031901	biolink:NamedThing	early endosome membrane	The lipid bilayer surrounding an early endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0038114	biolink:NamedThing	interleukin-21-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-21-mediated signaling pathway|interleukin-21-mediated signalling pathway						bf	2012-03-22T10:21:01Z						biological_process											owl:Class	
GO:0098757	biolink:NamedThing	cellular response to interleukin-21	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.	got7fsn_ti	cellular response to IL-21													biological_process											owl:Class	
GO:2000200	biolink:NamedThing	regulation of ribosomal subunit export from nucleus	Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus.	got7fsn_ti	regulation of ribosome export from nucleus|regulation of ribosomal subunit export from cell nucleus|regulation of ribosomal subunit transport from nucleus to cytoplasm|regulation of ribosomal subunit export out of nucleus|regulation of ribosomal subunit-nucleus export						mah	2010-10-26T10:44:27Z						biological_process											owl:Class	
CL:0000545	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900437	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.	got7fsn_ti							di	2012-04-25T05:55:17Z						biological_process											owl:Class	
GO:0031313	biolink:NamedThing	extrinsic component of endosome membrane	The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to endosome membrane													cellular_component											owl:Class	
GO:2000554	biolink:NamedThing	regulation of T-helper 1 cell cytokine production	Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production.	got7fsn_ti	regulation of Th1 cell cytokine production						ebc	2011-04-03T07:35:43Z						biological_process											owl:Class	
GO:1905426	biolink:NamedThing	positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.	got7fsn_ti	positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt signaling pathway involved in mDA neuron differentiation|upregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wg signalling pathway involved in mDA neuron differentiation|up regulation of frizzled signalling pathway involved in mDA neuron differentiation|activation of frizzled signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|up regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|up regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|upregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt-mediated midbrain DA neuron differentiation|positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt signaling pathway involved in mDA neuron differentiation|positive regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|activation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signalling pathway involved in midbrain DA neurogenesis|upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up regulation of frizzled signaling pathway involved in mDA neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wg signalling pathway involved in mDA neuron differentiation|upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signalling pathway involved in mDA neuron differentiation|activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of frizzled signalling pathway involved in mDA neuron differentiation|positive regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|up-regulation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|activation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signaling pathway involved in mDA neuron differentiation|activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt receptor signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wg signaling pathway involved in mDA neuron differentiation|activation of Wnt signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain DA neurogenesis|upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|upregulation of frizzled signaling pathway involved in midbrain DA neurogenesis|up regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|up regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|activation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt-mediated midbrain DA neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|activation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wg signaling pathway involved in mDA neuron differentiation|activation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|activation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt signaling pathway involved in mDA neuron differentiation|activation of Wnt-activated signaling pathway involved in mDA neuron differentiation|positive regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|upregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signalling pathway involved in mDA neuron differentiation|positive regulation of Wg signalling pathway involved in mDA neuron differentiation|activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signaling pathway involved in mDA neuron differentiation|upregulation of Wingless signaling pathway involved in mDA neuron differentiation|activation of Wg signalling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|activation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt-mediated midbrain DA neuron differentiation|positive regulation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of frizzled signaling pathway involved in mDA neuron differentiation|activation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signaling pathway involved in mDA neuron differentiation|up regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|upregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|activation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt signaling pathway involved in mDA neuron differentiation|activation of Wingless signaling pathway involved in midbrain DA neurogenesis|up regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|activation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signalling pathway involved in midbrain DA neurogenesis|activation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt-mediated midbrain DA neuron differentiation|positive regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wg signalling pathway involved in mDA neuron differentiation|up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signalling pathway involved in mDA neuron differentiation|up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wingless signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wg signaling pathway involved in midbrain DA neurogenesis|up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signaling pathway involved in midbrain DA neurogenesis|activation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|activation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|positive regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt-mediated midbrain DA neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wingless signalling pathway involved in mDA neuron differentiation|up regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of frizzled signaling pathway involved in mDA neuron differentiation|upregulation of Wingless signalling pathway involved in midbrain DA neurogenesis|activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|up regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signaling pathway involved in mDA neuron differentiation|up regulation of Wg signaling pathway involved in mDA neuron differentiation|up regulation of Wg signaling pathway involved in midbrain DA neurogenesis|up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of frizzled signalling pathway involved in mDA neuron differentiation|up regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt signaling pathway involved in mDA neuron differentiation|positive regulation of Wg signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wingless signalling pathway involved in mDA neuron differentiation|up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wnt signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signalling pathway involved in mDA neuron differentiation|positive regulation of midbrain dopaminergic neuron differentiation by positive regulation of Wnt signaling|up regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|activation of frizzled signaling pathway involved in mDA neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of frizzled signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of frizzled signalling pathway involved in mDA neuron differentiation						bf	2016-09-07T10:03:51Z						biological_process											owl:Class	
GO:0030145	biolink:NamedThing	manganese ion binding	Binding to a manganese ion (Mn).	got7fsn_ti	Mn binding|manganese binding													molecular_function											owl:Class	
GO:0004967	biolink:NamedThing	glucagon receptor activity	Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0071377	biolink:NamedThing	cellular response to glucagon stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.	got7fsn_ti							mah	2009-12-11T03:25:07Z						biological_process											owl:Class	
GO:0009509	biolink:NamedThing	chromoplast	A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.	got7fsn_ti												Wikipedia:Chromoplast		cellular_component											owl:Class	
GO:0090422	biolink:NamedThing	thiamine pyrophosphate transmembrane transporter activity	Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.	got7fsn_ti	thiamine pyrophosphate transporter activity|thiamine diphosphate transporter activity						tb	2012-04-17T12:28:11Z				Reactome:R-HSA-8875838		molecular_function											owl:Class	
GO:0030974	biolink:NamedThing	thiamine pyrophosphate transmembrane transport	The process in which thiamine pyrophosphate is transported across a membrane.	got7fsn_ti	thiamine pyrophosphate transport|thiamine diphosphate transport|thiamin diphosphate transport|thiamin pyrophosphate transport|TPP transport													biological_process											owl:Class	
GO:0006649	biolink:NamedThing	phospholipid transfer to membrane	The transfer of a phospholipid from its site of synthesis to the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0060034	biolink:NamedThing	notochord cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.	got7fsn_ti														biological_process											owl:Class	
GO:0099622	biolink:NamedThing	cardiac muscle cell membrane repolarization	The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.	got7fsn_ti														biological_process											owl:Class	
GO:0044640	biolink:NamedThing	envenomation resulting in negative regulation of complement activation, lectin pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism.	got7fsn_ti							jl	2012-07-05T04:56:30Z						biological_process											owl:Class	
GO:0097497	biolink:NamedThing	blood vessel endothelial cell delamination	The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet.	got7fsn_ti							pr	2013-08-12T13:48:34Z						biological_process											owl:Class	
GO:1990417	biolink:NamedThing	snoRNA release from pre-rRNA	The release of snoRNA from pre-rRNA.	got7fsn_ti					An example of this process is yeast HAS1 from PMID:16908538, inferred from mutant phenotype assay.		rb	2014-07-11T21:43:27Z						biological_process											owl:Class	
GO:0032474	biolink:NamedThing	otolith morphogenesis	The process in which the anatomical structures of an otolith are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0006264	biolink:NamedThing	mitochondrial DNA replication	The process in which new strands of DNA are synthesized in the mitochondrion.	got7fsn_ti	mitochondrial DNA synthesis|mtDNA replication|replication of mitochondrial DNA|mtDNA synthesis													biological_process											owl:Class	
GO:0039007	biolink:NamedThing	pronephric nephron morphogenesis	The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.	got7fsn_ti							bf	2010-07-02T09:38:53Z						biological_process											owl:Class	
GO:0003896	biolink:NamedThing	DNA primase activity	Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.	got7fsn_ti											GO:0003897|GO:0003898	EC:2.7.7.101		molecular_function											owl:Class	
GO:0021841	biolink:NamedThing	chemoattraction involved in interneuron migration from the subpallium to the cortex	The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex.	got7fsn_ti	positive chemotaxis involved in interneuron migration from the subpallium to the cortex													biological_process											owl:Class	
GO:0097613	biolink:NamedThing	dinoflagellate epicone	The part of a dinoflagellate cell above the cingulum; also referred to as the anterior portion of a dinoflagellate cell. It is separated from the hypocone by the cingulum.	got7fsn_ti	episome|epicone|epitheca				The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-06-09T11:32:48Z						cellular_component											owl:Class	
GO:1905934	biolink:NamedThing	negative regulation of cell fate determination	Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination.	got7fsn_ti	down regulation of cell fate determination|down-regulation of cell fate determination|inhibition of cell fate determination|downregulation of cell fate determination						bhm	2017-02-09T11:25:30Z						biological_process											owl:Class	
GO:0021815	biolink:NamedThing	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration	Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration.	got7fsn_ti	modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0008584	biolink:NamedThing	male gonad development	The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.	got7fsn_ti	testicular development|testis development													biological_process											owl:Class	
GO:0012510	biolink:NamedThing	trans-Golgi network transport vesicle membrane	The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.	got7fsn_ti	trans-Golgi network constitutive secretory pathway transport vesicle membrane|TGN transport vesicle membrane													cellular_component											owl:Class	
GO:0030140	biolink:NamedThing	trans-Golgi network transport vesicle	A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.	got7fsn_ti	trans-Golgi network constitutive secretory pathway transport vesicle|TGN transport vesicle													cellular_component											owl:Class	
GO:0090006	biolink:NamedThing	regulation of linear element assembly	Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase.	got7fsn_ti	regulation of linear element assembly						tb	2009-07-17T01:05:13Z						biological_process											owl:Class	
GO:0051232	biolink:NamedThing	meiotic spindle elongation	The lengthening of the distance between poles of the spindle during a meiotic cell cycle.	got7fsn_ti	spindle elongation during meiosis													biological_process											owl:Class	
GO:0060302	biolink:NamedThing	negative regulation of cytokine activity	Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.	got7fsn_ti														biological_process											owl:Class	
GO:0007182	biolink:NamedThing	common-partner SMAD protein phosphorylation	The process of introducing a phosphate group on to a common-partner SMAD protein. A common partner SMAD protein binds to pathway-restricted SMAD proteins forming a complex that translocates to the nucleus.	got7fsn_ti	common-mediator SMAD protein phosphorylation|common partner SMAD protein phosphorylation|common mediator SMAD protein phosphorylation|co-SMAD protein phosphorylation													biological_process											owl:Class	
GO:1905910	biolink:NamedThing	negative regulation of dauer entry	Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry.	got7fsn_ti	down-regulation of dauer entry|downregulation of dauer entry|down regulation of dauer entry|down regulation of nematode entry into dormancy|inhibition of dauer entry|downregulation of nematode entry into dormancy|inhibition of nematode entry into dormancy|down-regulation of nematode entry into dormancy|negative regulation of nematode entry into dormancy						hbye	2017-02-06T15:34:11Z						biological_process											owl:Class	
GO:0008429	biolink:NamedThing	phosphatidylethanolamine binding	Binding to a phosphatidylethanolamine, a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.	got7fsn_ti														molecular_function											owl:Class	
GO:0098866	biolink:NamedThing	multivesicular body fusion to apical plasma membrane	The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell.	got7fsn_ti														biological_process											owl:Class	
GO:0060441	biolink:NamedThing	epithelial tube branching involved in lung morphogenesis	The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.	got7fsn_ti	lung branching morphogenesis													biological_process											owl:Class	
GO:0002633	biolink:NamedThing	positive regulation of granuloma formation	Any process that activates or increases the frequency, rate, or extent of granuloma formation.	got7fsn_ti	up-regulation of granuloma formation|upregulation of granuloma formation|activation of granuloma formation|stimulation of granuloma formation|up regulation of granuloma formation													biological_process											owl:Class	
GO:0000802	biolink:NamedThing	transverse filament	A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them.	got7fsn_ti														cellular_component											owl:Class	
GO:1905951	biolink:NamedThing	mitochondrion DNA recombination	Any DNA recombination that takes place in mitochondrion.	got7fsn_ti	DNA recombination in mitochondria						vw	2017-02-19T10:48:17Z						biological_process											owl:Class	
GO:0097195	biolink:NamedThing	pilomotor reflex	The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect.	got7fsn_ti	goosebump reflex|piloerection|horripilation						pr	2011-12-01T05:08:14Z						biological_process											owl:Class	
GO:1990463	biolink:NamedThing	lateral cortical node	A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferase Skb1 in stoichiometric quantities, and may contain other proteins.	got7fsn_ti	Skb1-containing cortical node						pr	2014-08-20T09:04:45Z						cellular_component											owl:Class	
GO:0061405	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.	got7fsn_ti							dph	2012-01-10T03:24:51Z						biological_process											owl:Class	
GO:0061043	biolink:NamedThing	regulation of vascular wound healing	Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.	got7fsn_ti							dph	2010-02-25T10:21:59Z						biological_process											owl:Class	
GO:0060316	biolink:NamedThing	positive regulation of ryanodine-sensitive calcium-release channel activity	Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														biological_process											owl:Class	
GO:0048447	biolink:NamedThing	sepal morphogenesis	The process in which the anatomical structures of the sepal are generated and organized.	got7fsn_ti											GO:0048422			biological_process											owl:Class	
GO:1902417	biolink:NamedThing	(+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity	Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other.	got7fsn_ti	ABA-GE transmembrane transporter activity|abscisic acid glucosyl ester transmembrane transporter activity						tb	2013-09-16T22:37:11Z						molecular_function											owl:Class	
GO:1902418	biolink:NamedThing	(+)-abscisic acid D-glucopyranosyl ester transmembrane transport	The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane.	got7fsn_ti	abscisic acid glucosyl ester transmembrane transport|ABA-GE transmembrane transport						tb	2013-09-16T22:37:20Z						biological_process											owl:Class	
GO:0015208	biolink:NamedThing	guanine transmembrane transporter activity	Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0002555	biolink:NamedThing	histamine secretion by platelet	The regulated release of histamine by a platelet or group of platelets.	got7fsn_ti														biological_process											owl:Class	
GO:0051208	biolink:NamedThing	sequestering of calcium ion	The process of binding or confining calcium ions such that they are separated from other components of a biological system.	got7fsn_ti	calcium ion storage activity|sequestering of calcium ion (Ca2+)|calcium ion (Ca2+) storage|calcium ion (Ca2+) sequestration|negative regulation of calcium ion (Ca2+) transport|storage of calcium ion (Ca2+)|calcium ion (Ca2+) retention|retention of calcium ion (Ca2+)|calcium ion (Ca2+) sequestering|sequestration of calcium ion (Ca2+)													biological_process											owl:Class	
GO:0036316	biolink:NamedThing	SREBP-SCAP complex retention in endoplasmic reticulum	Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER.	got7fsn_ti					Consider also annotating to the cellular component term: SREBP-SCAP-Insig complex ; GO:0032937.		bf	2012-08-21T14:53:08Z						biological_process											owl:Class	
GO:0036315	biolink:NamedThing	cellular response to sterol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.	got7fsn_ti							bf	2012-08-21T14:51:21Z						biological_process											owl:Class	
GO:0016519	biolink:NamedThing	gastric inhibitory peptide receptor activity	Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein.	got7fsn_ti	GIP receptor activity|glucose-dependent insulinotropic polypeptide receptor activity													molecular_function											owl:Class	
GO:0044612	biolink:NamedThing	nuclear pore linkers	A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p).	got7fsn_ti	Nup82 complex|Nic96 complex						jl	2012-06-20T01:22:40Z						cellular_component											owl:Class	
GO:0001518	biolink:NamedThing	voltage-gated sodium channel complex	A sodium channel in a cell membrane whose opening is governed by the membrane potential.	got7fsn_ti	voltage-dependent sodium channel complex|voltage-sensitive sodium channel complex|voltage gated sodium channel complex											NIF_Subcellular:sao785001660		cellular_component											owl:Class	
PR:000035728	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060023	biolink:NamedThing	soft palate development	The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.	got7fsn_ti	palatum molle development|velum palatum development													biological_process											owl:Class	
GO:0003810	biolink:NamedThing	protein-glutamine gamma-glutamyltransferase activity	Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links.	got7fsn_ti	glutaminylpeptide gamma-glutamyltransferase activity|protein-glutamine:amine gamma-glutamyltransferase|factor XIIIa|R-glutaminyl-peptide:amine gamma-glutamyl transferase activity|polyamine transglutaminase activity|tissue transglutaminase|transglutaminase activity|TGase activity|fibrinoligase activity|fibrin stabilizing factor											RHEA:54816|MetaCyc:2.3.2.13-RXN|Reactome:R-HSA-6810894|Reactome:R-HSA-140851|RESID:AA0124|EC:2.3.2.13		molecular_function											owl:Class	
GO:0061076	biolink:NamedThing	negative regulation of neural retina development	Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.	got7fsn_ti							dph	2010-03-16T12:46:11Z						biological_process											owl:Class	
GO:0021682	biolink:NamedThing	nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.	got7fsn_ti														biological_process											owl:Class	
GO:0003404	biolink:NamedThing	optic vesicle morphogenesis	The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.	got7fsn_ti							dph	2009-12-21T01:54:34Z						biological_process											owl:Class	
CL:0000236	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120207	biolink:NamedThing	endocytosis, site selection	The process of selecting and or marking the position where endocytosis will occur.	got7fsn_ti							krc	2019-05-15T21:25:49Z						biological_process											owl:Class	
GO:0015763	biolink:NamedThing	N-acetylgalactosamine transport	The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.	got7fsn_ti														biological_process											owl:Class	
GO:0009349	biolink:NamedThing	riboflavin synthase complex	An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine.	got7fsn_ti														cellular_component											owl:Class	
GO:0097572	biolink:NamedThing	right nucleus	One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side.	got7fsn_ti					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-18T11:23:01Z						cellular_component											owl:Class	
GO:0036389	biolink:NamedThing	bacterial pre-replicative complex	A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.	got7fsn_ti	bacterial pre-RC						bf	2013-06-05T16:41:47Z						cellular_component											owl:Class	
GO:0035475	biolink:NamedThing	angioblast cell migration involved in selective angioblast sprouting	The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.	got7fsn_ti							bf	2010-04-23T10:04:30Z						biological_process											owl:Class	
GO:1990906	biolink:NamedThing	accessory outer segment	A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors.	got7fsn_ti							dph	2015-11-24T13:56:06Z						cellular_component											owl:Class	
GO:0046627	biolink:NamedThing	negative regulation of insulin receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.	got7fsn_ti	downregulation of insulin receptor signaling pathway|negative regulation of insulin receptor signalling pathway|down-regulation of insulin receptor signaling pathway|down regulation of insulin receptor signaling pathway|inhibition of insulin receptor signaling pathway													biological_process											owl:Class	
GO:0030049	biolink:NamedThing	muscle filament sliding	The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.	got7fsn_ti														biological_process											owl:Class	
GO:0004705	biolink:NamedThing	JUN kinase activity	Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.	got7fsn_ti	JNK|JNK3alpha1|SAPK1|c-Jun N-terminal kinase activity											Reactome:R-HSA-205132|Reactome:R-HSA-9673789|Reactome:R-HSA-168136|Reactome:R-HSA-204949|Reactome:R-HSA-205075		molecular_function											owl:Class	
GO:0140384	biolink:NamedThing	metacyclogenesis	The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania.	got7fsn_ti							pg	2019-11-20T13:25:55Z						biological_process											owl:Class	
NCBITaxon:5654	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044105	biolink:NamedThing	L-xylulose reductase (NAD+) activity	Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21874					jl	2009-07-09T04:25:43Z						molecular_function											owl:Class	
GO:0048725	biolink:NamedThing	cibarial fish-trap bristle development	The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.	got7fsn_ti	fish-trap bristle development													biological_process											owl:Class	
GO:0070124	biolink:NamedThing	mitochondrial translational initiation	The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.	got7fsn_ti	mitochondrial translation initiation													biological_process											owl:Class	
GO:0110016	biolink:NamedThing	B-WICH complex	A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself.	got7fsn_ti					An example is BAZ1B (Q9UIG0) in human in PMID:16603771 (by IPI).		kmv	2017-05-26T19:53:53Z						cellular_component											owl:Class	
GO:1990188	biolink:NamedThing	euchromatin binding	Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.	got7fsn_ti							tb	2013-09-11T19:18:38Z						molecular_function											owl:Class	
GO:1990813	biolink:NamedThing	meiotic centromeric cohesion protection	The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation after cohesin is cleaved by separase along the arm regions.	got7fsn_ti	protection of centromeric cohesion during meiotic anaphase I						vw	2015-07-28T16:15:31Z						biological_process											owl:Class	
GO:0051455	biolink:NamedThing	monopolar spindle attachment to meiosis I kinetochore	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs.	got7fsn_ti	sister kinetochore mono-orientation|attachment of spindle microtubules to kinetochore involved in meiosis I|attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|attachment of spindle microtubules to kinetochore during meiosis I|monopolar attachment				Note that the synonym 'monopolar attachment' refers to the normal attachment of sister chromosomes to the spindle in meiosis I, and not to the aberrant attachment of sister kinetochores to a single pole in mitosis.									biological_process											owl:Class	
GO:0140416	biolink:NamedThing	transcription regulator inhibitor activity	A molecular function regulator that inhibits the activity of a transcription regulator via direct binding and/or post-translational modification.	got7fsn_ti	DNA-binding transcription factor inhibitor activity	https://github.com/geneontology/go-ontology/issues/18596|https://github.com/geneontology/go-ontology/issues/16132			Usage guidance: transcription regulator inhibitors bind to a transcription regulator to prevent it from reaching the chromatin. This activity does not occur at the promoter. For activities that do occur at the promoter, consider GO:0001217 ; DNA-binding transcription repressor activity or GO:0003714 ; transcription corepressor activity. An example of a transcription regulator is TCF23 Q7RTU1 is an example of a protein that regulates transcription factors by heterodimerising or binding to DbTFs and prevent DNA binding and their specific genomic binding site where the dbTF would have activated or repressed transcription. Also an example is NFKBIA P25963 which has a different way of regulating transcription factor activity by sequestering the dbTF (complex) in the cytoplasm. Another example is the HSP90 and HSP23 proteins that sequester steroid receptors away from the DNA.		pg	2020-01-21T14:17:39Z						molecular_function											owl:Class	
GO:0021837	biolink:NamedThing	motogenic signaling involved in postnatal olfactory bulb interneuron migration	The signaling that results in the stimulation of cell movement in the rostral migratory stream.	got7fsn_ti	motogenic signalling involved in postnatal olfactory bulb interneuron migration													biological_process											owl:Class	
GO:0005621	biolink:NamedThing	cellular bud scar	Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.	got7fsn_ti														cellular_component											owl:Class	
GO:0062041	biolink:NamedThing	positive regulation of meiotic sister chromatid arm separation	Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.	got7fsn_ti							dph	2018-05-04T18:20:28Z						biological_process											owl:Class	
GO:0010449	biolink:NamedThing	root meristem growth	The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root.	got7fsn_ti														biological_process											owl:Class	
GO:0048766	biolink:NamedThing	root hair initiation	The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.	got7fsn_ti														biological_process											owl:Class	
GO:1901039	biolink:NamedThing	regulation of peptide antigen transport	Any process that modulates the frequency, rate or extent of peptide antigen transport.	got7fsn_ti							bf	2012-06-22T04:07:56Z						biological_process											owl:Class	
GO:0043373	biolink:NamedThing	CD4-positive, alpha-beta T cell lineage commitment	The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.	got7fsn_ti	CD4-positive, alpha-beta T lymphocyte lineage commitment|CD4-positive, alpha-beta T-cell lineage commitment|CD4-positive, alpha-beta T-lymphocyte lineage commitment													biological_process											owl:Class	
GO:0031641	biolink:NamedThing	regulation of myelination	Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.	got7fsn_ti														biological_process											owl:Class	
GO:0008147	biolink:NamedThing	structural constituent of bone	The action of a molecule that contributes to the structural integrity of bone.	got7fsn_ti														molecular_function											owl:Class	
GO:0098646	biolink:NamedThing	collagen sheet	A protein complex that consists of collagen triple helices associated to form a sheet-like network.	got7fsn_ti	collagen hexagonal network													cellular_component											owl:Class	
GO:0033263	biolink:NamedThing	CORVET complex	A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.	got7fsn_ti														cellular_component											owl:Class	
GO:0009344	biolink:NamedThing	nitrite reductase complex [NAD(P)H]	Complex that possesses nitrite reductase [NAD(P)H] activity.	got7fsn_ti					See also the molecular function term 'nitrite reductase [NAD(P)H] activity ; GO:0008942'.									cellular_component											owl:Class	
GO:1990406	biolink:NamedThing	CGRP receptor complex	A transmembrane, G protein-coupled signalling receptor complex recognized by calcitonin gene-related peptides (CGRP).	got7fsn_ti	calcitonin gene-related polypeptide receptor complex|CGRP-R complex|Calcitonin-gene-related peptide receptor complex				An example of this is CALCRL in human (Q16602) in PMID:20826335 (inferred from direct assay).		bhm	2014-07-01T14:57:43Z						cellular_component											owl:Class	
GO:0045629	biolink:NamedThing	negative regulation of T-helper 2 cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.	got7fsn_ti	negative regulation of T-helper 2 cell development|down regulation of T-helper 2 cell differentiation|downregulation of T-helper 2 cell differentiation|down-regulation of T-helper 2 cell differentiation|inhibition of T-helper 2 cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1990629	biolink:NamedThing	phospholamban complex	A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.	got7fsn_ti	cardiac PLB complex|cardiac phospholamban complex|cardiac PLN complex				An example of this is PLN in human (UniProt symbol P26678) in PMID:16043693 (inferred from direct assay).		ame	2015-02-05T14:12:36Z						cellular_component											owl:Class	
GO:1902080	biolink:NamedThing	regulation of calcium ion import into sarcoplasmic reticulum	Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.	got7fsn_ti							rl	2013-04-24T16:07:50Z						biological_process											owl:Class	
GO:0030745	biolink:NamedThing	dimethylhistidine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.	got7fsn_ti	histidine-alpha-N-methyltransferase activity|dimethylhistidine methyltransferase activity|S-adenosyl-L-methionine:alpha-N,alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity|S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine nalpha-methyltransferase activity											MetaCyc:2.1.1.44-RXN|EC:2.1.1.44|RHEA:11104|KEGG_REACTION:R04436		molecular_function											owl:Class	
GO:1990461	biolink:NamedThing	detoxification of iron ion	Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.	got7fsn_ti							sart	2014-08-19T10:12:46Z						biological_process											owl:Class	
GO:0010039	biolink:NamedThing	response to iron ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.	got7fsn_ti	response to iron													biological_process											owl:Class	
GO:0035444	biolink:NamedThing	nickel cation transmembrane transport	The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore.	got7fsn_ti	nickel cation membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-13T09:22:51Z						biological_process											owl:Class	
GO:0004586	biolink:NamedThing	ornithine decarboxylase activity	Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.	got7fsn_ti	L-ornithine carboxy-lyase activity|SpeC|L-ornithine carboxy-lyase (putrescine-forming)											EC:4.1.1.17|Reactome:R-HSA-70692|MetaCyc:ORNDECARBOX-RXN|KEGG_REACTION:R00670|RHEA:22964		molecular_function											owl:Class	
GO:0014807	biolink:NamedThing	regulation of somitogenesis	Any process that modulates the frequency, rate or extent of somitogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:1990159	biolink:NamedThing	DnaB-DnaC-DnaT-PriA-PriC complex	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.	got7fsn_ti	DnaB-DnaC-DnaT-PriA-PriC preprimosome|phi-X174-type preprimosome						bhm	2013-08-02T11:58:16Z						cellular_component											owl:Class	
GO:0000801	biolink:NamedThing	central element	A structural unit of the synaptonemal complex found between the lateral elements.	got7fsn_ti														cellular_component											owl:Class	
GO:0060461	biolink:NamedThing	right lung morphogenesis	The process in which anatomical structures of the right lung are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0033673	biolink:NamedThing	negative regulation of kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	got7fsn_ti	inhibition of kinase activity|down-regulation of kinase activity|downregulation of kinase activity|down regulation of kinase activity|kinase inhibitor													biological_process											owl:Class	
GO:0099041	biolink:NamedThing	vesicle tethering to Golgi	The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes.  Interaction can occur via direct binding  to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.	got7fsn_ti							tb	2013-01-08T15:07:50Z						biological_process											owl:Class	
GO:0038031	biolink:NamedThing	non-canonical Wnt signaling pathway via JNK cascade	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade.	got7fsn_ti	non-canonical Wnt receptor signaling pathway via JNK cascade|non-canonical Wnt receptor signalling pathway via JNK cascade|non-canonical Wnt-activated signaling pathway via JNK cascade						bf	2011-09-08T01:57:10Z						biological_process											owl:Class	
GO:1901247	biolink:NamedThing	negative regulation of lung ciliated cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation.	got7fsn_ti	downregulation of lung ciliated cell differentiation|inhibition of lung ciliated cell differentiation|down-regulation of lung ciliated cell differentiation|down regulation of lung ciliated cell differentiation						vk	2012-08-08T08:58:58Z						biological_process											owl:Class	
GO:1902436	biolink:NamedThing	negative regulation of male mating behavior	Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior.	got7fsn_ti	inhibition of male mating behavior|down-regulation of male mating behavior|down regulation of male mating behavior|downregulation of male mating behavior						mm2	2013-10-09T15:50:05Z						biological_process											owl:Class	
GO:0042707	biolink:NamedThing	ocellus photoreceptor cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.	got7fsn_ti														biological_process											owl:Class	
GO:0042705	biolink:NamedThing	ocellus photoreceptor cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.	got7fsn_ti														biological_process											owl:Class	
GO:0071118	biolink:NamedThing	alphaV-beta3 integrin-NOV complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV.	got7fsn_ti	ITGAV-ITGB3-FN-1-NOV complex						mah	2009-11-13T02:20:20Z						cellular_component											owl:Class	
GO:0001533	biolink:NamedThing	cornified envelope	A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes).	got7fsn_ti														cellular_component											owl:Class	
GO:0030509	biolink:NamedThing	BMP signaling pathway	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	decapentaplegic signaling pathway|BMP receptor signaling pathway|dpp signaling pathway|decapentaplegic receptor signaling pathway|BMP signalling pathway|decapentaplegic receptor signalling pathway|dpp receptor signalling pathway|dpp receptor signaling pathway|bone morphogenetic protein signaling pathway|bone morphogenetic protein signalling pathway										GO:0008101			biological_process											owl:Class	
GO:0030299	biolink:NamedThing	intestinal cholesterol absorption	Uptake of cholesterol into the blood by absorption from the small intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0036390	biolink:NamedThing	pre-replicative complex assembly involved in bacterial-type DNA replication	The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.	got7fsn_ti	bacterial pre-RC assembly|bacterial pre-replicative complex assembly						bf	2013-06-05T16:45:21Z						biological_process											owl:Class	
GO:0042753	biolink:NamedThing	positive regulation of circadian rhythm	Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.	got7fsn_ti	activation of circadian rhythm|up regulation of circadian rhythm|up-regulation of circadian rhythm|upregulation of circadian rhythm|stimulation of circadian rhythm													biological_process											owl:Class	
GO:0045320	biolink:NamedThing	chloroplast proton-transporting ATP synthase complex	A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation.	got7fsn_ti	chloroplast hydrogen-translocating F-type ATPase complex|chloroplast proton-transporting F-type ATPase complex|hydrogen-translocating F-type ATPase complex													cellular_component											owl:Class	
GO:0098775	biolink:NamedThing	curli assembly	The process of assembly of curli, extracellular fibers produced by enteric bacteria.  This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex.	got7fsn_ti														biological_process											owl:Class	
GO:0072276	biolink:NamedThing	metanephric glomerulus vasculature morphogenesis	The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.	got7fsn_ti							mah	2010-04-01T02:47:32Z						biological_process											owl:Class	
GO:0072275	biolink:NamedThing	metanephric glomerulus morphogenesis	The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.	got7fsn_ti							mah	2010-04-01T02:46:58Z						biological_process											owl:Class	
GO:0045501	biolink:NamedThing	regulation of sevenless signaling pathway	Any process that modulates the frequency, rate or extent of the sevenless signaling pathway.	got7fsn_ti	regulation of sev signaling pathway|regulation of sevenless signalling pathway													biological_process											owl:Class	
GO:0071557	biolink:NamedThing	histone H3-K27 demethylation	The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone.	got7fsn_ti	H3K27 demethylation						mah	2010-01-15T10:59:50Z						biological_process											owl:Class	
GO:0090611	biolink:NamedThing	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.  This process is independent of ubiquitination.	got7fsn_ti							tb	2014-10-23T15:27:12Z						biological_process											owl:Class	
GO:0035183	biolink:NamedThing	female germline ring canal inner rim	A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.	got7fsn_ti	germline ring canal inner rim|ovarian ring canal inner rim|nurse cell ring canal inner rim				See also the fly_anatomy.ontology term 'inner nurse cell ring canal rim ; FBbt:00004881'.									cellular_component											owl:Class	
GO:0004505	biolink:NamedThing	phenylalanine 4-monooxygenase activity	Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.	got7fsn_ti	L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)|phenylalanine 4-hydroxylase activity|phenylalaninase activity|phenylalanine hydroxylase activity|PAH activity	https://github.com/geneontology/go-ontology/issues/20583										MetaCyc:PHENYLALANINE-4-MONOOXYGENASE-RXN|EC:1.14.16.1|RHEA:20273|Reactome:R-HSA-5649483|Reactome:R-HSA-71118		molecular_function											owl:Class	
GO:0097120	biolink:NamedThing	receptor localization to synapse	Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.	got7fsn_ti	receptor localisation to synapse						pr	2011-07-31T09:20:30Z						biological_process											owl:Class	
GO:0021829	biolink:NamedThing	oligodendrocyte cell migration from the subpallium to the cortex	The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development.	got7fsn_ti														biological_process											owl:Class	
CL:0000128	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014714	biolink:NamedThing	myoblast fate commitment in head	The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0021724	biolink:NamedThing	inferior raphe nucleus development	The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure.	got7fsn_ti	inferior central nucleus development|posterior raphe nucleus development													biological_process											owl:Class	
GO:1904145	biolink:NamedThing	negative regulation of meiotic cell cycle process involved in oocyte maturation	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.	got7fsn_ti	down regulation of meiotic cell cycle process involved in oocyte maturation|inhibition of meiotic cell cycle process involved in oocyte maturation|downregulation of meiotic cell cycle process involved in oocyte maturation|down-regulation of meiotic cell cycle process involved in oocyte maturation						tb	2015-04-14T15:59:22Z						biological_process											owl:Class	
GO:0030089	biolink:NamedThing	phycobilisome	Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II.	got7fsn_ti												Wikipedia:Phycobilisome		cellular_component											owl:Class	
CL:0002085	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902747	biolink:NamedThing	negative regulation of lens fiber cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation.	got7fsn_ti	negative regulation of lens fibre cell differentiation|down-regulation of lens fiber cell differentiation|inhibition of lens fibre cell differentiation|downregulation of lens fiber cell differentiation|down regulation of lens fibre cell differentiation|downregulation of lens fibre cell differentiation|down regulation of lens fiber cell differentiation|down-regulation of lens fibre cell differentiation|inhibition of lens fiber cell differentiation						mr	2014-03-03T23:19:32Z						biological_process											owl:Class	
GO:0032284	biolink:NamedThing	plastid biotin carboxylase complex	A biotin carboxylase complex located in the stroma of a plastid.	got7fsn_ti														cellular_component											owl:Class	
GO:0001653	biolink:NamedThing	peptide receptor activity	Combining with an extracellular or intracellular peptide to initiate a change in cell activity.	got7fsn_ti	endogenous peptide receptor activity|exogenous peptide receptor activity													molecular_function											owl:Class	
GO:0005784	biolink:NamedThing	Sec61 translocon complex	A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events.	got7fsn_ti	Sec61p-Sbh1p-Sss1p complex													cellular_component											owl:Class	
GO:0061268	biolink:NamedThing	mesonephric interstitial fibroblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.	got7fsn_ti							dph	2010-08-30T03:16:52Z						biological_process											owl:Class	
CL:0000601	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048448	biolink:NamedThing	stamen morphogenesis	The process in which the anatomical structures of the stamen are generated and organized.	got7fsn_ti											GO:0048426			biological_process											owl:Class	
GO:0010865	biolink:NamedThing	stipule development	The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms.	got7fsn_ti														biological_process											owl:Class	
GO:0048340	biolink:NamedThing	paraxial mesoderm morphogenesis	The process in which the anatomical structures of the paraxial mesoderm are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0035155	biolink:NamedThing	negative regulation of terminal cell fate specification, open tracheal system	Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.	got7fsn_ti	inhibition of terminal cell fate specification|downregulation of terminal cell fate specification|down regulation of terminal cell fate specification|negative regulation of terminal cell fate specification|down-regulation of terminal cell fate specification													biological_process											owl:Class	
GO:0033340	biolink:NamedThing	pelvic fin development	The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0140092	biolink:NamedThing	bBAF complex	A brain-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes. Compared to the neuron-specific nBAF complex (GO:0071565) it does not contain DPF1, DPF3 or SMARCC1 or their orthologs. May contain PB1/BAF180.	got7fsn_ti	brain-specific SWI/SNF complex|brain-specific BAF complex						pg	2017-09-05T09:22:41Z						cellular_component											owl:Class	
GO:0005686	biolink:NamedThing	U2 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U2, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U2 snRNP, most of which remain associated with the U2 snRNA both while the U2 snRNP is free or assembled into a series of spliceosomal complexes.	got7fsn_ti	17S U2 snRNP|snRNP U2				U2 snRNP refers to the U2 small nuclear RNA and the proteins that associate with it. U2 snRNP is not considered to be a type of spliceosomal complex by itself.									cellular_component											owl:Class	
GO:0048090	biolink:NamedThing	negative regulation of female pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.	got7fsn_ti	down regulation of female pigmentation|downregulation of female pigmentation|inhibition of female pigmentation|down-regulation of female pigmentation													biological_process											owl:Class	
GO:0098954	biolink:NamedThing	presynaptic endosome membrane	The lipid bilayer surrounding a presynaptic endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0098830	biolink:NamedThing	presynaptic endosome	An endosome present in the presynapse that fuses with endocytic vesicles arising in the presynaptic endocytic zone.  This organelle is believed to be involved in regeneration of synaptic vesicles.	got7fsn_ti					As of 2015, there is still controversy over the nature of presynaptic endosomes and their relationship to regular endosomes.  See Jahne et al., 2015 (PMID:25939282) for details.									cellular_component											owl:Class	
GO:0060473	biolink:NamedThing	cortical granule	A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.	got7fsn_ti	cortical vesicle													cellular_component											owl:Class	
GO:1901891	biolink:NamedThing	regulation of cell septum assembly	Any process that modulates the frequency, rate or extent of cell septum assembly.	got7fsn_ti							tb	2013-02-06T20:14:40Z						biological_process											owl:Class	
GO:1990501	biolink:NamedThing	exon-exon junction subcomplex mago-y14	Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA.	got7fsn_ti	MGN-RBM8A complex|mago-y14 complex|exon junction subcomplex MAGOH-Y14				An example of this is Mago in drome (P49028) in PMID:12730685 (inferred from direct assay).		bhm	2014-09-30T14:05:28Z						cellular_component											owl:Class	
GO:0043066	biolink:NamedThing	negative regulation of apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	got7fsn_ti	down-regulation of apoptosis|inhibition of apoptosis|pro-survival|down regulation of apoptosis|anti-apoptosis|apoptosis inhibitor activity|downregulation of apoptosis|negative regulation of apoptosis				This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.						GO:0006916			biological_process											owl:Class	
GO:0075525	biolink:NamedThing	viral translational termination-reinitiation	A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF.	got7fsn_ti	termination reinitiation involved in viral translation|viral translation involving termination re-initiation|viral translation involving termination-reinitiation|viral translation involving translational stop-start				This term is intended to annotate gene products involved in the process of viral translational termination-reinitiation, not viral proteins produced by this translation process.		jl	2011-08-04T12:01:22Z				VZ:858		biological_process											owl:Class	
GO:0061033	biolink:NamedThing	secretion by lung epithelial cell involved in lung growth	The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.	got7fsn_ti	fetal lung liquid secretion						dph	2010-02-09T10:02:55Z						biological_process											owl:Class	
GO:0005369	biolink:NamedThing	taurine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in).	got7fsn_ti	sodium/chloride-dependent taurine transporter													molecular_function											owl:Class	
NCBITaxon:716545	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990202	biolink:NamedThing	FMN reductase complex	A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer.	got7fsn_ti	SsuE complex|flavin oxidoreductase complex, NAD(P)H-dependent|FMN reductase complex, NAD(P)H-dependent|FMN oxidoreductase complex, NAD(P)H-dependent						bhm	2013-10-03T15:07:20Z						cellular_component											owl:Class	
GO:0098578	biolink:NamedThing	condensed chromatin of inactivated sex chromosome	A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation.	got7fsn_ti														cellular_component											owl:Class	
GO:0016037	biolink:NamedThing	light absorption	The reception of a photon by a cell.	got7fsn_ti	absorption of light													biological_process											owl:Class	
GO:0015011	biolink:NamedThing	nickel-tetrapyrrole coenzyme metabolic process	The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase.	got7fsn_ti	nickel-tetrapyrrole coenzyme metabolism|coenzyme F430 metabolic process													biological_process											owl:Class	
GO:0098974	biolink:NamedThing	postsynaptic actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.	got7fsn_ti														biological_process											owl:Class	
GO:0019911	biolink:NamedThing	structural constituent of myelin sheath	The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve.	got7fsn_ti														molecular_function											owl:Class	
GO:0099579	biolink:NamedThing	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential.	got7fsn_ti	G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential													molecular_function											owl:Class	
GO:0015976	biolink:NamedThing	carbon utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.	got7fsn_ti	heterotrophy|carbon utilization by utilization of organic compounds										GO:0015978	Wikipedia:Heterotroph		biological_process											owl:Class	
GO:0033285	biolink:NamedThing	ATPase-coupled monocarboxylic acid transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).	got7fsn_ti	monocarboxylic acid-transporting ATPase activity|ATP-dependent monocarboxylic acid transmembrane transporter activity													molecular_function											owl:Class	
GO:0099162	biolink:NamedThing	regulation of neurotransmitter loading into synaptic vesicle	Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.	got7fsn_ti	regulation of synaptic vesicle neurotransmitter loading|regulation of neurotransmitter uptake into synaptic vesicle						dos	2017-09-10T11:07:57Z						biological_process											owl:Class	
GO:0061644	biolink:NamedThing	protein localization to CENP-A containing chromatin	Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin.	got7fsn_ti							dph	2014-08-29T12:17:05Z						biological_process											owl:Class	
GO:1904349	biolink:NamedThing	positive regulation of small intestine smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction.	got7fsn_ti	activation of small intestine smooth muscle contraction|up regulation of small intestine smooth muscle contraction|upregulation of small intestine smooth muscle contraction|up-regulation of small intestine smooth muscle contraction						sl	2015-06-11T21:37:46Z						biological_process											owl:Class	
GO:0009923	biolink:NamedThing	fatty acid elongase complex	A tetrameric complex of four different subunits which catalyzes the elongation of fatty acids chains 2 carbon units at a time in the synthesis of very long chain fatty acids.	got7fsn_ti														cellular_component											owl:Class	
GO:0009761	biolink:NamedThing	CAM photosynthesis	The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis.	got7fsn_ti												Wikipedia:Crassulacean_acid_metabolism		biological_process											owl:Class	
GO:0021639	biolink:NamedThing	trochlear nerve morphogenesis	The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	got7fsn_ti	CH IV morphogenesis													biological_process											owl:Class	
GO:0016019	biolink:NamedThing	peptidoglycan immune receptor activity	Combining with a peptidoglycan and transmitting the signal to initiate an innate immune response.	got7fsn_ti	peptidoglycan receptor activity|peptidoglycan recognition activity				Note that only peptidoglycan recognition proteins with receptor activity should be annotated to this term; otherwise use 'peptidoglycan binding ; GO:0042834' instead.									molecular_function											owl:Class	
GO:0042834	biolink:NamedThing	peptidoglycan binding	Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.	got7fsn_ti														molecular_function											owl:Class	
GO:0046549	biolink:NamedThing	retinal cone cell development	Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.	got7fsn_ti														biological_process											owl:Class	
GO:0042670	biolink:NamedThing	retinal cone cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.	got7fsn_ti														biological_process											owl:Class	
GO:0003174	biolink:NamedThing	mitral valve development	The progression of the mitral valve over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-08T11:17:22Z						biological_process											owl:Class	
GO:0070585	biolink:NamedThing	protein localization to mitochondrion	A process in which a protein is transported to, or maintained in, a location within the mitochondrion.	got7fsn_ti	protein localization in mitochondrion|protein localisation in mitochondrion						mah	2009-04-24T02:31:18Z						biological_process											owl:Class	
GO:0060942	biolink:NamedThing	neural crest-derived cardiac fibroblast cell differentiation	The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T01:54:19Z						biological_process											owl:Class	
GO:0060783	biolink:NamedThing	mesenchymal smoothened signaling pathway involved in prostate gland development	The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.	got7fsn_ti	mesenchymal hedgehog signaling pathway involved in prostate gland development|mesenchymal hh signaling pathway involved in prostate gland development|mesenchymal smoothened signalling pathway involved in prostate gland development						dph	2009-07-28T11:57:59Z						biological_process											owl:Class	
GO:0060738	biolink:NamedThing	epithelial-mesenchymal signaling involved in prostate gland development	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time.	got7fsn_ti	epithelial-mesenchymal signalling involved in prostate gland development						dph	2009-06-15T09:31:31Z						biological_process											owl:Class	
GO:0090256	biolink:NamedThing	regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis	Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.	got7fsn_ti							tb	2010-01-22T11:40:46Z						biological_process											owl:Class	
GO:0090255	biolink:NamedThing	cell proliferation involved in imaginal disc-derived wing morphogenesis	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.	got7fsn_ti							tb	2010-01-22T11:40:46Z						biological_process											owl:Class	
CHEBI:17855	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002533	biolink:NamedThing	lysosomal enzyme secretion involved in inflammatory response	The regulated release of lysosomal enzymes by a cell as part of an inflammatory response.	got7fsn_ti	secretion of lysosomal enzymes involved in acute inflammatory response|secretion of lysosomal enzymes involved in inflammatory response|lysosomal enzyme secretion involved in acute inflammatory response													biological_process											owl:Class	
GO:0002393	biolink:NamedThing	lysosomal enzyme production involved in inflammatory response	The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels.	got7fsn_ti	lysosomal enzyme production involved in acute inflammatory response|production of lysosomal enzymes involved in inflammatory response|production of lysosomal enzymes involved in acute inflammatory response													biological_process											owl:Class	
GO:0048501	biolink:NamedThing	signal recognition particle, plasma membrane targeting	A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0035354	biolink:NamedThing	Toll-like receptor 1-Toll-like receptor 2 protein complex	A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).	got7fsn_ti	TLR1:TLR2 complex|TLR1-TLR2 protein complex|TLR2:TLR1 heterodimer|toll-like receptor TLR1:TLR2 heterodimeric complex						bf	2010-03-04T04:35:44Z			GO:0038125			cellular_component											owl:Class	
GO:0008815	biolink:NamedThing	citrate (pro-3S)-lyase activity	Catalysis of the reaction: citrate = acetate + oxaloacetate.	got7fsn_ti	citrate lyase activity|citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]|citratase activity|citrate lyase|citrate aldolase activity|citrate oxaloacetate-lyase activity|citridesmolase activity|citric aldolase activity|citrase activity|citritase activity											KEGG_REACTION:R00362|RHEA:10760|MetaCyc:CITLY-RXN|EC:4.1.3.6		molecular_function											owl:Class	
GO:2000044	biolink:NamedThing	negative regulation of cardiac cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification.	got7fsn_ti							tb	2010-08-19T09:01:10Z						biological_process											owl:Class	
GO:0110034	biolink:NamedThing	negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway.	got7fsn_ti	negative regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway						kmv	2017-07-17T20:35:55Z						biological_process											owl:Class	
GO:0071769	biolink:NamedThing	mycolate cell wall layer assembly	The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer.	got7fsn_ti	mycolate cell wall layer biogenesis						mah	2010-03-29T04:40:45Z				MetaCyc:PWY-6397		biological_process											owl:Class	
GO:0071212	biolink:NamedThing	subsynaptic reticulum	An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.	got7fsn_ti	SSR						mah	2009-12-01T05:05:21Z						cellular_component											owl:Class	
GO:0072267	biolink:NamedThing	metanephric capsule specification	The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti							mah	2010-03-30T02:57:36Z						biological_process											owl:Class	
GO:0072266	biolink:NamedThing	metanephric capsule formation	The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	got7fsn_ti							mah	2010-03-30T02:56:35Z						biological_process											owl:Class	
GO:2000057	biolink:NamedThing	negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.	got7fsn_ti	negative regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis|negative regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis|negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis						jl	2010-08-20T01:17:35Z						biological_process											owl:Class	
GO:0098683	biolink:NamedThing	cochlear hair cell ribbon synapse	A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density.	got7fsn_ti							dos	2017-02-05T16:16:49Z						cellular_component											owl:Class	
CL:0000202	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070088	biolink:NamedThing	PHA granule	An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR.	got7fsn_ti	PHB granule|polyhydroxyalkanoate granule													cellular_component											owl:Class	
GO:0015151	biolink:NamedThing	alpha-glucoside transmembrane transporter activity	Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.	got7fsn_ti														molecular_function											owl:Class	
GO:0000017	biolink:NamedThing	alpha-glucoside transport	The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.	got7fsn_ti														biological_process											owl:Class	
GO:0035688	biolink:NamedThing	T-helper 1 cell diapedesis	The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.	got7fsn_ti	Th1 cell diapedesis						bf	2011-02-24T10:12:11Z						biological_process											owl:Class	
GO:0140599	biolink:NamedThing	mitotic nuclear bridge midzone membrane domain	A nuclear membrane part at the midzone of the mitotic nuclear bridge. The midzone forms a bulge that is enriched in nuclear pores that lack baskets.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20526					pg	2021-02-10T13:39:43Z						cellular_component											owl:Class	
GO:0006271	biolink:NamedThing	DNA strand elongation involved in DNA replication	The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication.	got7fsn_ti	DNA strand elongation during DNA replication|DNA replication elongation	https://github.com/geneontology/go-ontology/issues/12633												biological_process											owl:Class	
GO:0071729	biolink:NamedThing	beak morphogenesis	The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.	got7fsn_ti							mah	2010-03-17T03:54:34Z						biological_process											owl:Class	
GO:0031262	biolink:NamedThing	Ndc80 complex	An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.	got7fsn_ti	Nuf2-Ndc80 complex													cellular_component											owl:Class	
GO:0038043	biolink:NamedThing	interleukin-5-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	interleukin-5-mediated signalling pathway|IL-5-mediated signaling pathway						bf	2011-11-03T04:18:21Z						biological_process											owl:Class	
GO:0000426	biolink:NamedThing	micropexophagy	Degradation of a peroxisome by lysosomal microautophagy.	got7fsn_ti					Note that this term is not a child of pexophagy because the community usually uses the latter to refer to the macroautohagy process.									biological_process											owl:Class	
GO:1905683	biolink:NamedThing	peroxisome disassembly	The disaggregation of a peroxisome into its constituent components.	got7fsn_ti	peroxisomal disassembly						pr	2016-11-14T10:09:15Z						biological_process											owl:Class	
GO:0051082	biolink:NamedThing	unfolded protein binding	Binding to an unfolded protein.	got7fsn_ti	chaperone activity	https://github.com/geneontology/go-ontology/issues/21436										Reactome:R-HSA-9683772|Reactome:R-HSA-9694337		molecular_function											owl:Class	
GO:0016992	biolink:NamedThing	lipoate synthase activity	Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl.	got7fsn_ti	lipoyl synthase activity|LS|protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity|lipoic acid synthase|protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity|LipA										GO:0017140	EC:2.8.1.8|RHEA:16585|Reactome:R-HSA-6793591|MetaCyc:RXN0-949		molecular_function											owl:Class	
GO:0009107	biolink:NamedThing	lipoate biosynthetic process	The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.	got7fsn_ti	lipoate biosynthesis|lipoic acid biosynthetic process|lipoic acid anabolism|lipoate formation|lipoate synthesis|lipoic acid synthesis|lipoic acid biosynthesis|lipoic acid formation|lipoate anabolism										GO:0009105			biological_process											owl:Class	
GO:0048728	biolink:NamedThing	proboscis development	The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure.	got7fsn_ti											GO:0016349			biological_process											owl:Class	
GO:0042650	biolink:NamedThing	prothylakoid membrane	The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes.	got7fsn_ti														cellular_component											owl:Class	
GO:0046818	biolink:NamedThing	dense nuclear body	A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously.	got7fsn_ti														cellular_component											owl:Class	
GO:0007227	biolink:NamedThing	signal transduction downstream of smoothened	The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway.	got7fsn_ti														biological_process											owl:Class	
GO:0070143	biolink:NamedThing	mitochondrial alanyl-tRNA aminoacylation	The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0005334	biolink:NamedThing	norepinephrine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in).	got7fsn_ti	noradrenaline transporter activity|norepinephrine transmembrane transporter activity|norepinephrine:sodium:chloride symporter activity|norepinephrine:sodium symporter activity|levarterenol transporter activity|sodium/norepinephrine symporter activity										GO:0005333	Reactome:R-HSA-5659764|Reactome:R-HSA-443997|Wikipedia:Norepinephrine_transporter		molecular_function											owl:Class	
GO:0051620	biolink:NamedThing	norepinephrine uptake	The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.	got7fsn_ti	noradrenaline uptake|norepinephrine reuptake|noradrenaline reuptake|levarterenol reuptake|levarterenol uptake|norepinephrine import													biological_process											owl:Class	
GO:0060308	biolink:NamedThing	GTP cyclohydrolase I regulator activity	Binds to and modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0044549	biolink:NamedThing	GTP cyclohydrolase binding	Binding to a GTP cyclohydrolase.	got7fsn_ti	GTP cyclohydrolase I binding						jl	2012-03-22T04:38:14Z			GO:0043106			molecular_function											owl:Class	
GO:0140516	biolink:NamedThing	mitotic nuclear pore complex disassembly	The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis.	got7fsn_ti	nuclear pore complex disassembly during mitosis	https://github.com/geneontology/go-ontology/issues/19947					pg	2020-09-09T15:29:01Z						biological_process											owl:Class	
NCBITaxon:5658	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034121	biolink:NamedThing	regulation of toll-like receptor signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.	got7fsn_ti	regulation of TLR signaling pathway|regulation of toll-like receptor signalling pathway													biological_process											owl:Class	
GO:0042078	biolink:NamedThing	germ-line stem cell division	The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.	got7fsn_ti	germ-line stem cell renewal										GO:0048131			biological_process											owl:Class	
GO:0016483	biolink:NamedThing	tryptophan hydroxylase activator activity	Increases the activity of the enzyme tryptophase hydroxylase.	got7fsn_ti														molecular_function											owl:Class	
GO:0060528	biolink:NamedThing	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate.	got7fsn_ti														biological_process											owl:Class	
GO:0060525	biolink:NamedThing	prostate glandular acinus development	The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.	got7fsn_ti														biological_process											owl:Class	
GO:0046528	biolink:NamedThing	imaginal disc fusion	The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis.	got7fsn_ti														biological_process											owl:Class	
GO:0015211	biolink:NamedThing	purine nucleoside transmembrane transporter activity	Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015860	biolink:NamedThing	purine nucleoside transmembrane transport	The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.	got7fsn_ti	purine nucleoside transport|purine nucleoside membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.						GO:0035427			biological_process											owl:Class	
GO:1990395	biolink:NamedThing	meiotic spindle pole body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body.	got7fsn_ti							tb	2014-06-06T01:41:05Z						biological_process											owl:Class	
GO:0000212	biolink:NamedThing	meiotic spindle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.	got7fsn_ti	meiotic spindle organisation|meiotic spindle organization and biogenesis|meiotic spindle stabilization|spindle organization during meiosis										GO:0043147			biological_process											owl:Class	
GO:0014041	biolink:NamedThing	regulation of neuron maturation	Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.	got7fsn_ti														biological_process											owl:Class	
GO:0014716	biolink:NamedThing	skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration	Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt.	got7fsn_ti	satellite cell asymmetric division involved in skeletal muscle regeneration				Occurrence of this process outside of the context of muscle repair is probably very rare, so there is a good case for merging this with the parent class.									biological_process											owl:Class	
GO:0004198	biolink:NamedThing	calcium-dependent cysteine-type endopeptidase activity	Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.	got7fsn_ti	calpain activity											Reactome:R-HSA-8848658|Reactome:R-HSA-8863012		molecular_function											owl:Class	
GO:0007094	biolink:NamedThing	mitotic spindle assembly checkpoint signaling	A signal transduction process that contributes to a mitotic cell cycle spindle assembly checkpoint, that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.	got7fsn_ti	mitotic checkpoint|signal transduction involved in mitotic cell cycle spindle assembly checkpoint|mitotic cell cycle spindle assembly checkpoint|signaling cascade involved in SAC-independent checkpoint|signaling pathway involved in Dma1-dependent checkpoint|signalling cascade involved in SAC-independent checkpoint|Mad2-dependent checkpoint|mitotic spindle assembly checkpoint signalling|signalling pathway involved in SAC-independent checkpoint|mitotic spindle assembly checkpoint|signalling pathway involved in Dma1-dependent checkpoint|signal transduction involved in mitotic spindle assembly checkpoint|signalling cascade involved in Dma1-dependent checkpoint|signal transduction involved in SAC-independent checkpoint|signaling pathway involved in SAC-independent checkpoint|signal transduction involved in Dma1-dependent checkpoint|SAC-independent checkpoint|Dma1-dependent checkpoint|signaling cascade involved in Dma1-dependent checkpoint|mitotic spindle assembly checkpoint signaling	https://github.com/geneontology/go-ontology/issues/19810|https://github.com/geneontology/go-ontology/issues/20935									GO:0072480|GO:0044810|GO:1902420			biological_process											owl:Class	
GO:0005461	biolink:NamedThing	UDP-glucuronic acid transmembrane transporter activity	Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.	got7fsn_ti												Reactome:R-HSA-174368|Reactome:R-HSA-5603297		molecular_function											owl:Class	
GO:0015787	biolink:NamedThing	UDP-glucuronic acid transmembrane transport	The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-glucuronic acid transport													biological_process											owl:Class	
GO:0019191	biolink:NamedThing	cellobiose transmembrane transporter activity	Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.	got7fsn_ti	cellobiose permease activity										GO:0019190			molecular_function											owl:Class	
GO:0019533	biolink:NamedThing	cellobiose transport	The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.	got7fsn_ti														biological_process											owl:Class	
GO:0010419	biolink:NamedThing	rhamnogalacturonan II side chain metabolic process	The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively.	got7fsn_ti	rhamnogalacturonan II side chain metabolism													biological_process											owl:Class	
GO:0062077	biolink:NamedThing	phenylacetyl-CoA 1,2-epoxidase complex	A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+).	got7fsn_ti	paaABCE complex						dph	2018-09-27T12:40:04Z						cellular_component											owl:Class	
GO:0010124	biolink:NamedThing	phenylacetate catabolic process	The chemical reactions and pathways resulting in the breakdown of phenylacetate.	got7fsn_ti	phenylacetate degradation|phenylacetate breakdown|phenylacetate catabolism											MetaCyc:PWY0-321		biological_process											owl:Class	
GO:0043661	biolink:NamedThing	peribacteroid membrane	A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).	got7fsn_ti														cellular_component											owl:Class	
GO:1903074	biolink:NamedThing	TRAIL death-inducing signaling complex assembly	The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.	got7fsn_ti	TRAIL DISC formation|TRAIL DISC assembly|TRAIL death-inducing signalling complex formation|TRAIL death-inducing signalling complex assembly|TRAIL death-inducing signaling complex formation						bf	2014-05-29T09:47:39Z						biological_process											owl:Class	
GO:0036462	biolink:NamedThing	TRAIL-activated apoptotic signaling pathway	An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface.	got7fsn_ti	TRAIL-activated extrinsic apoptotic signaling pathway|tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|TRAIL-induced apoptotic signaling pathway						bf	2014-06-11T09:18:41Z						biological_process											owl:Class	
GO:0000487	biolink:NamedThing	maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0005898	biolink:NamedThing	interleukin-13 receptor complex	A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain.	got7fsn_ti	IL-13 receptor complex													cellular_component											owl:Class	
GO:0060483	biolink:NamedThing	lobar bronchus mesenchyme development	The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.	got7fsn_ti														biological_process											owl:Class	
GO:0060482	biolink:NamedThing	lobar bronchus development	The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.	got7fsn_ti														biological_process											owl:Class	
GO:0120010	biolink:NamedThing	intermembrane phospholipid transfer	The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-16T20:56:03Z						biological_process											owl:Class	
GO:0045063	biolink:NamedThing	T-helper 1 cell differentiation	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.	got7fsn_ti	T-helper 1 cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0048561	biolink:NamedThing	establishment of animal organ orientation	The process that determines the orientation of an animal organ or tissue with reference to an axis.	got7fsn_ti														biological_process											owl:Class	
GO:0098638	biolink:NamedThing	laminin binding involved in cell-matrix adhesion	Any laminin protein binding that occurs as part of cell-matrix adhesion.	got7fsn_ti														molecular_function											owl:Class	
GO:0044660	biolink:NamedThing	viral release by cytolysis via pore formation in host cell membrane	The killing by a virus of a cell in its host organism by cytolysis, caused by the formation by the virus of pores in its host cell membrane.	got7fsn_ti	cytolysis by virus via pore formation in host cell membrane|viral exit by cytolysis via pore formation in host cell membrane	https://github.com/geneontology/go-ontology/issues/18852					jl	2012-08-01T13:23:41Z						biological_process											owl:Class	
GO:0035069	biolink:NamedThing	larval midgut histolysis	The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.	got7fsn_ti	larval midgut regression													biological_process											owl:Class	
GO:0002042	biolink:NamedThing	cell migration involved in sprouting angiogenesis	The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:0048861	biolink:NamedThing	leukemia inhibitory factor signaling pathway	Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	leukemia inhibitory factor signalling pathway													biological_process											owl:Class	
GO:1901547	biolink:NamedThing	negative regulation of synaptic vesicle lumen acidification	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification.	got7fsn_ti	negative regulation of proton loading|down-regulation of synaptic vesicle lumen acidification|down regulation of synaptic vesicle lumen acidification|down-regulation of synaptic vesicle lumen pH reduction|inhibition of synaptic vesicle lumen acidification|negative regulation of synaptic vesicle lumen pH reduction|downregulation of synaptic vesicle lumen pH reduction|down regulation of synaptic vesicle lumen pH reduction|inhibition of synaptic vesicle lumen pH reduction|downregulation of synaptic vesicle lumen acidification						dsf	2012-10-26T16:09:28Z						biological_process											owl:Class	
GO:0014866	biolink:NamedThing	skeletal myofibril assembly	The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.	got7fsn_ti														biological_process											owl:Class	
GO:0031150	biolink:NamedThing	sorocarp stalk development	The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	stalk formation|stalk development|sorophore development													biological_process											owl:Class	
GO:0021731	biolink:NamedThing	trigeminal motor nucleus development	The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0002915	biolink:NamedThing	negative regulation of central B cell anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.	got7fsn_ti	downregulation of central B cell anergy|down regulation of central B cell anergy|down-regulation of central B cell anergy|inhibition of central B cell anergy													biological_process											owl:Class	
GO:0099586	biolink:NamedThing	release of sequestered calcium ion into postsynaptic cytosol	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:0002785	biolink:NamedThing	negative regulation of antimicrobial peptide production	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.	got7fsn_ti	downregulation of antimicrobial peptide production|inhibition of antimicrobial peptide production|down-regulation of antimicrobial peptide production|down regulation of antimicrobial peptide production													biological_process											owl:Class	
GO:1904094	biolink:NamedThing	positive regulation of autophagic cell death	Any process that activates or increases the frequency, rate or extent of autophagic cell death.	got7fsn_ti	up regulation of programmed cell death by macroautophagy|activation of type II programmed cell death|positive regulation of type II programmed cell death|up-regulation of autophagic cell death|upregulation of type II programmed cell death|upregulation of programmed cell death by macroautophagy|activation of programmed cell death by macroautophagy|up regulation of autophagic cell death|positive regulation of programmed cell death by macroautophagy|upregulation of autophagic cell death|activation of autophagic cell death|up-regulation of programmed cell death by macroautophagy|up-regulation of type II programmed cell death|up regulation of type II programmed cell death						bhm	2015-03-26T16:41:45Z						biological_process											owl:Class	
GO:0048928	biolink:NamedThing	posterior lateral line ganglion neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.	got7fsn_ti														biological_process											owl:Class	
GO:2000054	biolink:NamedThing	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.	got7fsn_ti	negative regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|negative regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification						jl	2010-08-20T01:13:35Z						biological_process											owl:Class	
GO:1904626	biolink:NamedThing	positive regulation of glycine secretion, neurotransmission	Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission.	got7fsn_ti	upregulation of glycine secretion, neurotransmission|up-regulation of glycine secretion, neurotransmission|up regulation of glycine secretion, neurotransmission|activation of glycine secretion, neurotransmission						hjd	2015-08-27T20:03:49Z						biological_process											owl:Class	
GO:1901075	biolink:NamedThing	negative regulation of engulfment of apoptotic cell	Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell.	got7fsn_ti	down-regulation of engulfment of apoptotic cell corpse|down regulation of engulfment of apoptotic cell corpse|inhibition of engulfment of apoptotic cell corpse|downregulation of engulfment of apoptotic cell|inhibition of engulfment of cell corpse|down regulation of engulfment of apoptotic cell|negative regulation of engulfment of cell corpse|down-regulation of engulfment of apoptotic cell|downregulation of engulfment of cell corpse|down regulation of engulfment of cell corpse|negative regulation of engulfment of apoptotic cell corpse|inhibition of engulfment of apoptotic cell|downregulation of engulfment of apoptotic cell corpse|down-regulation of engulfment of cell corpse						kmv	2012-07-02T07:32:43Z						biological_process											owl:Class	
GO:0001058	biolink:NamedThing	RNA polymerase V activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase V promoter						krc	2010-09-23T03:45:01Z						molecular_function											owl:Class	
GO:0001060	biolink:NamedThing	transcription by RNA polymerase V	The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter.	got7fsn_ti	transcription from RNA pol V promoter|transcription from RNA polymerase V promoter	https://github.com/geneontology/go-ontology/issues/14854					krc	2010-09-23T03:54:04Z						biological_process											owl:Class	
GO:0043313	biolink:NamedThing	regulation of neutrophil degranulation	Any process that modulates the frequency, rate, or extent of neutrophil degranulation.	got7fsn_ti	regulation of neutrophil granule exocytosis													biological_process											owl:Class	
GO:0043282	biolink:NamedThing	pharyngeal muscle development	The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.	got7fsn_ti														biological_process											owl:Class	
GO:0060465	biolink:NamedThing	pharynx development	The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.	got7fsn_ti	pharyngeal development													biological_process											owl:Class	
GO:1903704	biolink:NamedThing	negative regulation of production of siRNA involved in RNA interference	Any process that stops, prevents or reduces the frequency, rate or extent of production of siRNA involved in RNA interference.	got7fsn_ti	negative regulation of RNA interference, production of siRNA|down regulation of production of guide RNAs involved in RNA interference|negative regulation of production of guide RNAs involved in RNA interference|downregulation of production of guide RNAs involved in RNA interference|inhibition of production of guide RNAs involved in RNA interference|negative regulation of RNA interference, production of guide RNAs|inhibition of production of siRNA involved in RNA interference|down-regulation of RNA interference, production of siRNA|down-regulation of RNA interference, production of guide RNAs|inhibition of RNA interference, production of siRNA|downregulation of RNA interference, production of siRNA|downregulation of RNA interference, production of guide RNAs|downregulation of production of siRNA involved in RNA interference|inhibition of RNA interference, production of guide RNAs|down regulation of RNA interference, production of guide RNAs|down-regulation of production of guide RNAs involved in RNA interference|down regulation of production of siRNA involved in RNA interference|down regulation of RNA interference, production of siRNA|down-regulation of production of siRNA involved in RNA interference						nc	2014-12-03T15:13:22Z						biological_process											owl:Class	
GO:0033596	biolink:NamedThing	TSC1-TSC2 complex	A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.	got7fsn_ti	tuberin-hamartin complex|tuberous sclerosis complex													cellular_component											owl:Class	
GO:0015614	biolink:NamedThing	ABC-type D-xylose transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in).	got7fsn_ti	D-xylose porter activity|ATPase-coupled D-xylose transmembrane transporter activity|D-xylose-importing ATPase activity											RHEA:29899|EC:7.5.2.10		molecular_function											owl:Class	
GO:1990962	biolink:NamedThing	xenobiotic transport across blood-brain barrier	The directed movement of a xenobiotic through the blood-brain barrier.	got7fsn_ti	drug transport across blood-brain barrier						sl	2016-06-07T17:39:33Z						biological_process											owl:Class	
GO:0140525	biolink:NamedThing	antipodal site	The pole of the kinetoplast associated with kinetoplast DNA replication. The antipodal sites flank the kinetoplast DNA disk and are positioned approximately 180 degrees apart. In Trypanosoma brucei and Crithidia fasciculata, minicircles are attached at antipodal sites and they contain enzymes that catalyse some of the later reactions in minicircle replication.	got7fsn_ti	antipodal zone	https://github.com/geneontology/go-ontology/issues/20036					pg	2020-09-29T08:01:53Z						cellular_component											owl:Class	
GO:0042320	biolink:NamedThing	regulation of circadian sleep/wake cycle, REM sleep	Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep.	got7fsn_ti	regulation of REM sleep													biological_process											owl:Class	
GO:0097448	biolink:NamedThing	spine mat	A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma.	got7fsn_ti							pr	2012-12-17T12:34:16Z				NIF_Subcellular:sao2128156969		cellular_component											owl:Class	
GO:0033581	biolink:NamedThing	protein galactosylation in Golgi	The addition of a galactose unit to a protein amino acid in any compartment of the Golgi apparatus.	got7fsn_ti	protein amino acid galactosylation in Golgi													biological_process											owl:Class	
GO:0016348	biolink:NamedThing	imaginal disc-derived leg joint morphogenesis	The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:1903237	biolink:NamedThing	negative regulation of leukocyte tethering or rolling	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling.	got7fsn_ti	down-regulation of leukocyte tethering or rolling|inhibition of leukocyte tethering or rolling|downregulation of leukocyte tethering or rolling|down regulation of leukocyte tethering or rolling						als	2014-07-31T13:07:55Z						biological_process											owl:Class	
GO:0052619	biolink:NamedThing	coenzyme F420-1:gamma-L-glutamate ligase activity	Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate.	got7fsn_ti												MetaCyc:RXN-8081|RHEA:30523|EC:6.3.2.34		molecular_function											owl:Class	
CL:0000312	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060221	biolink:NamedThing	retinal rod cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.	got7fsn_ti														biological_process											owl:Class	
GO:0071016	biolink:NamedThing	U12-type precatalytic spliceosome	A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.	got7fsn_ti	AT-AC precatalytic spliceosome|mammalian U12-type spliceosomal complex B|mammalian U12-type spliceosomal complex B1|minor precatalytic spliceosome|yeast U12-type spliceosomal complex A2-1						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0005692	biolink:NamedThing	U11 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U11, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U11 snRNP, most of which remain associated with the U11 snRNA both while the U11 snRNP is free or assembled into a series of spliceosomal complexes.	got7fsn_ti	12S U11 snRNP|snRNP U11													cellular_component											owl:Class	
GO:0004703	biolink:NamedThing	G protein-coupled receptor kinase activity	Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate.	got7fsn_ti	G protein-coupled receptor kinase activity|G-protein coupled receptor kinase activity|GRK6|GRK5|GPCRK|ATP:G-protein-coupled receptor phosphotransferase activity|STK16|GPCR kinase activity|GPCR phosphorylating protein kinase activity|G protein coupled receptor phosphorylating protein kinase activity|G-protein-coupled receptor phosphorylating protein kinase activity|GRK4										GO:0004678	RHEA:12008|EC:2.7.11.16		molecular_function											owl:Class	
GO:0019645	biolink:NamedThing	anaerobic electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient.	got7fsn_ti														biological_process											owl:Class	
GO:0032785	biolink:NamedThing	negative regulation of DNA-templated transcription, elongation	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.	got7fsn_ti	negative regulation of transcriptional elongation|negative regulation of transcription elongation|downregulation of RNA elongation|down-regulation of RNA elongation|down regulation of RNA elongation|inhibition of RNA elongation|negative transcription elongation regulator activity|negative regulation of DNA-dependent transcription, elongation|negative regulation of transcription elongation, DNA-dependent													biological_process											owl:Class	
GO:0001956	biolink:NamedThing	positive regulation of neurotransmitter secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.	got7fsn_ti	up regulation of neurotransmitter secretion|activation of neurotransmitter secretion|upregulation of neurotransmitter secretion|stimulation of neurotransmitter secretion|up-regulation of neurotransmitter secretion													biological_process											owl:Class	
GO:0140302	biolink:NamedThing	pollen-style interaction	The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte.	got7fsn_ti							pg	2019-02-22T13:59:33Z						biological_process											owl:Class	
PO:0025281	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045178	biolink:NamedThing	basal part of cell	The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.	got7fsn_ti														cellular_component											owl:Class	
GO:0006294	biolink:NamedThing	nucleotide-excision repair, preincision complex assembly	The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.	got7fsn_ti	nucleotide-excision repair, preincision complex formation													biological_process											owl:Class	
GO:2000248	biolink:NamedThing	negative regulation of establishment or maintenance of neuroblast polarity	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity.	got7fsn_ti	negative regulation of establishment and/or maintenance of neuroblast cell polarity						vw	2010-11-11T11:40:34Z						biological_process											owl:Class	
GO:0090307	biolink:NamedThing	mitotic spindle assembly	Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.	got7fsn_ti	spindle assembly involved in mitosis						tb	2010-04-09T11:31:28Z						biological_process											owl:Class	
GO:2000201	biolink:NamedThing	negative regulation of ribosomal subunit export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus.	got7fsn_ti	negative regulation of ribosome export from nucleus|negative regulation of ribosomal subunit transport from nucleus to cytoplasm|negative regulation of ribosomal subunit export out of nucleus|negative regulation of ribosomal subunit-nucleus export|negative regulation of ribosomal subunit export from cell nucleus						mah	2010-10-26T10:44:32Z						biological_process											owl:Class	
GO:0036092	biolink:NamedThing	phosphatidylinositol-3-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.	got7fsn_ti	PI(3)P biosynthesis|phosphatidylinositol-3-phosphate formation|PtdIns3P biosynthesis|phosphatidylinositol-3-phosphate biosynthesis|phosphatidylinositol-3-phosphate synthesis|phosphatidylinositol-3-phosphate anabolism						bf	2012-01-13T02:13:57Z						biological_process											owl:Class	
GO:0060691	biolink:NamedThing	epithelial cell maturation involved in salivary gland development	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.	got7fsn_ti							dph	2009-06-08T01:06:00Z						biological_process											owl:Class	
GO:0060690	biolink:NamedThing	epithelial cell differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.	got7fsn_ti							dph	2009-06-08T01:04:19Z						biological_process											owl:Class	
GO:0001409	biolink:NamedThing	guanine nucleotide transmembrane transporter activity	Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:1903790	biolink:NamedThing	guanine nucleotide transmembrane transport	The process in which a guanyl nucleotide is transported across a membrane.	got7fsn_ti	guanyl nucleotide transmembrane transport						dph	2015-01-10T13:51:54Z						biological_process											owl:Class	
GO:0097222	biolink:NamedThing	mitochondrial mRNA polyadenylation	The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails.	got7fsn_ti							pr	2012-01-24T02:47:19Z						biological_process											owl:Class	
GO:0150052	biolink:NamedThing	regulation of postsynapse assembly	Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse.	got7fsn_ti							bc	2018-05-08T16:38:55Z						biological_process											owl:Class	
GO:0010787	biolink:NamedThing	COPI coating of Golgi vesicle, inter-Golgi cisterna	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat.	got7fsn_ti														biological_process											owl:Class	
GO:0046943	biolink:NamedThing	carboxylic acid transmembrane transporter activity	Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).	got7fsn_ti												Reactome:R-HSA-390347		molecular_function											owl:Class	
GO:1905039	biolink:NamedThing	carboxylic acid transmembrane transport	The process in which carboxylic acid is transported across a membrane.	got7fsn_ti							vw	2016-03-09T15:33:53Z						biological_process											owl:Class	
GO:0120155	biolink:NamedThing	MIH complex	A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins.	got7fsn_ti	Mlc1p-Iqg1p-Hof1p complex						krc	2018-05-01T17:50:23Z						cellular_component											owl:Class	
GO:0048934	biolink:NamedThing	peripheral nervous system neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0046928	biolink:NamedThing	regulation of neurotransmitter secretion	Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0003186	biolink:NamedThing	tricuspid valve morphogenesis	The process in which the structure of the tricuspid valve is generated and organized.	got7fsn_ti							dph	2009-10-08T12:05:45Z						biological_process											owl:Class	
GO:0051974	biolink:NamedThing	negative regulation of telomerase activity	Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).	got7fsn_ti	down regulation of telomerase activity|down-regulation of telomerase activity|inhibition of telomerase activity|telomerase inhibitor|downregulation of telomerase activity													biological_process											owl:Class	
GO:0000938	biolink:NamedThing	GARP complex	A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles.	got7fsn_ti	Golgi associated retrograde protein complex|Vps fifty three tethering complex|VFT tethering complex													cellular_component											owl:Class	
GO:0034098	biolink:NamedThing	VCP-NPL4-UFD1 AAA ATPase complex	A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).	got7fsn_ti	p97-Ufd1-Npl4 complex|Cdc48p-Npl4p-Ufd1p AAA ATPase complex													cellular_component											owl:Class	
GO:1902961	biolink:NamedThing	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.	got7fsn_ti	up-regulation of aspartic protease activity involved in APP catabolism|up-regulation of aspartic-type endopeptidase activity involved in APP catabolic process|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|upregulation of carboxyl protease activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in APP catabolism|activation of aspartate protease activity involved in APP catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartic-type endopeptidase activity involved in APP catabolic process|up-regulation of aspartic protease activity involved in amyloid precursor protein degradation|up regulation of aspartate protease activity involved in APP catabolic process|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartate protease activity involved in APP catabolic process|activation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|positive regulation of aspartic-type endopeptidase activity involved in APP catabolism|upregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|activation of aspartic protease activity involved in APP catabolism|positive regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartic protease activity involved in APP catabolism|positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|activation of aspartate protease activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|activation of aspartic-type endopeptidase activity involved in APP catabolic process|upregulation of aspartyl protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartyl protease activity involved in APP catabolism|positive regulation of aspartic endopeptidase activity involved in APP catabolism|up regulation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartate protease activity involved in amyloid precursor protein degradation|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|activation of carboxyl protease activity involved in APP catabolic process|upregulation of aspartate protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartic protease activity involved in amyloid precursor protein catabolism|activation of carboxyl protease activity involved in amyloid precursor protein degradation|up regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein catabolism|positive regulation of carboxyl protease activity involved in amyloid precursor protein degradation|activation of aspartyl protease activity involved in amyloid precursor protein catabolic process|activation of aspartic protease activity involved in amyloid precursor protein breakdown|activation of aspartyl protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartate protease activity involved in APP catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartyl protease activity involved in amyloid precursor protein degradation|up regulation of aspartyl protease activity involved in amyloid precursor protein degradation|activation of aspartic protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartic protease activity involved in APP catabolism|up regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of aspartic endopeptidase activity involved in APP catabolic process|upregulation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartate protease activity involved in amyloid precursor protein degradation|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of carboxyl protease activity involved in amyloid precursor protein degradation|up regulation of carboxyl protease activity involved in amyloid precursor protein degradation|activation of aspartyl protease activity involved in amyloid precursor protein catabolism|activation of aspartate protease activity involved in APP catabolism|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|activation of aspartic protease activity involved in APP catabolic process|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|positive regulation of aspartate protease activity involved in APP catabolic process|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|up regulation of aspartic endopeptidase activity involved in APP catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic-type endopeptidase activity involved in APP catabolism|up-regulation of aspartate protease activity involved in APP catabolism|activation of aspartate protease activity involved in amyloid precursor protein catabolism|positive regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|activation of carboxyl protease activity involved in APP catabolism|positive regulation of aspartic protease activity involved in amyloid precursor protein catabolism|activation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|activation of carboxyl protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|upregulation of aspartic-type endopeptidase activity involved in APP catabolism|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|positive regulation of carboxyl protease activity involved in APP catabolism|up regulation of carboxyl protease activity involved in APP catabolic process|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartyl protease activity involved in APP catabolic process|up-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartyl protease activity involved in APP catabolic process|activation of aspartyl protease activity involved in APP catabolic process|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|positive regulation of aspartic protease activity involved in amyloid precursor protein breakdown|up-regulation of carboxyl protease activity involved in APP catabolism|positive regulation of aspartate protease activity involved in amyloid precursor protein breakdown|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|positive regulation of carboxyl protease activity involved in APP catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein degradation|positive regulation of aspartate protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|activation of aspartate protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic protease activity involved in APP catabolic process|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic protease activity involved in APP catabolic process|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|activation of aspartic endopeptidase activity involved in APP catabolism|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|up regulation of aspartic-type endopeptidase activity involved in APP catabolic process|up-regulation of aspartyl protease activity involved in APP catabolism|activation of aspartic-type endopeptidase activity involved in APP catabolism|up regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|upregulation of aspartate protease activity involved in APP catabolism|activation of carboxyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic-type endopeptidase activity involved in APP catabolic process|positive regulation of aspartic endopeptidase activity involved in APP catabolic process|upregulation of aspartyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|up regulation of aspartic protease activity involved in APP catabolism|activation of aspartic endopeptidase activity involved in APP catabolic process|positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|upregulation of carboxyl protease activity involved in amyloid precursor protein catabolism|activation of aspartate protease activity involved in amyloid precursor protein breakdown|upregulation of aspartyl protease activity involved in APP catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic endopeptidase activity involved in APP catabolic process|activation of aspartic protease activity involved in amyloid precursor protein degradation|up-regulation of aspartate protease activity involved in amyloid precursor protein breakdown|activation of carboxyl protease activity involved in amyloid precursor protein catabolic process|upregulation of carboxyl protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of carboxyl protease activity involved in APP catabolism|positive regulation of aspartic protease activity involved in amyloid precursor protein degradation|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of carboxyl protease activity involved in APP catabolic process|up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartate protease activity involved in APP catabolism|up regulation of aspartic protease activity involved in APP catabolic process|upregulation of aspartate protease activity involved in amyloid precursor protein degradation|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of aspartyl protease activity involved in amyloid precursor protein degradation|up-regulation of aspartyl protease activity involved in amyloid precursor protein degradation|up-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartate protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartate protease activity involved in amyloid precursor protein catabolism|activation of aspartyl protease activity involved in amyloid precursor protein degradation|activation of aspartyl protease activity involved in APP catabolism|positive regulation of aspartic protease activity involved in APP catabolic process|up regulation of aspartic-type endopeptidase activity involved in APP catabolism|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartyl protease activity involved in APP catabolic process|up regulation of aspartate protease activity involved in APP catabolism|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|up regulation of carboxyl protease activity involved in APP catabolism|upregulation of carboxyl protease activity involved in APP catabolic process|up regulation of aspartate protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of aspartyl protease activity involved in APP catabolism						sjp	2014-05-06T09:07:17Z						biological_process											owl:Class	
GO:0060042	biolink:NamedThing	retina morphogenesis in camera-type eye	The process in which the anatomical structure of the retina is generated and organized.	got7fsn_ti	retinogenesis|retina morphogenesis in camera-style eye													biological_process											owl:Class	
GO:0015446	biolink:NamedThing	ATPase-coupled arsenite transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).	got7fsn_ti	arsenite-transmembrane transporting ATPase activity|arsenite transporting ATPase activity|arsenite ABC transporter|arsenical resistance ATPase activity|arsenite-translocating ATPase activity|arsenical resistance efflux pump|arsenical pump-driving ATPase activity|arsenite-transporting ATPase activity				EC:7.3.2.7 states that this bacterial transporter does not belong to the ABC superfamily, and instead is a member of its own family, referred to as the Ars family. Like ABC transporters, it contains two nucleotide binding sites (PMID:10970874).							TC:3.A.4.1.1|MetaCyc:3.6.3.16-RXN|RHEA:11348|EC:7.3.2.7		molecular_function											owl:Class	
GO:0015700	biolink:NamedThing	arsenite transport	The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0035694	biolink:NamedThing	mitochondrial protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.	got7fsn_ti	catabolism of mitochondrial protein|degradation of damaged mitochondrial protein						bf	2011-02-28T11:06:40Z						biological_process											owl:Class	
GO:0015772	biolink:NamedThing	oligosaccharide transport	The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	got7fsn_ti														biological_process											owl:Class	
GO:0060393	biolink:NamedThing	regulation of pathway-restricted SMAD protein phosphorylation	Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	got7fsn_ti														biological_process											owl:Class	
GO:0071656	biolink:NamedThing	negative regulation of granulocyte colony-stimulating factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor.	got7fsn_ti	negative regulation of pluripoietin production|negative regulation of CSF3 production|negative regulation of granulocyte colony stimulating factor production|negative regulation of filgrastim production|negative regulation of lenograstim production|negative regulation of colony stimulating factor 3 (granulocyte) production|negative regulation of G-CSF production						mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:0071611	biolink:NamedThing	granulocyte colony-stimulating factor production	The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	granulocyte colony stimulating factor production|colony stimulating factor 3 (granulocyte) production|filgrastim production|lenograstim production|CSF3 production|G-CSF production|pluripoietin production						mah	2010-02-05T04:38:11Z						biological_process											owl:Class	
GO:1905141	biolink:NamedThing	negative regulation of apical ectodermal ridge formation	Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation.	got7fsn_ti	inhibition of crista ectodermalis apicalis formation|inhibition of apical epidermal ridge formation|inhibition of AER formation|inhibition of apical ectodermal ridge formation|down regulation of apical epidermal ridge formation|down-regulation of AER formation|negative regulation of crista ectodermalis apicalis formation|down regulation of AER formation|downregulation of AER formation|negative regulation of AER formation|down regulation of crista ectodermalis apicalis formation|downregulation of crista ectodermalis apicalis formation|down regulation of apical ectodermal ridge formation|downregulation of apical epidermal ridge formation|down-regulation of crista ectodermalis apicalis formation|downregulation of apical ectodermal ridge formation|negative regulation of apical epidermal ridge formation|down-regulation of apical ectodermal ridge formation|down-regulation of apical epidermal ridge formation						dph	2016-04-13T12:16:48Z						biological_process											owl:Class	
GO:0072690	biolink:NamedThing	single-celled organism vegetative growth phase	A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods.	got7fsn_ti	stationary phase|vegetative growth of a single-celled organism	https://github.com/geneontology/go-ontology/issues/18275			Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).		mah	2011-08-19T12:05:19Z			GO:0062178			biological_process											owl:Class	
NCBITaxon:Union_0000023	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051035	biolink:NamedThing	DNA transmembrane transporter activity	Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0051027	biolink:NamedThing	DNA transport	The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1900400	biolink:NamedThing	regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter	A regulation of transcription from RNA polymerase II promoter that results in regulation of iron ion import.	got7fsn_ti	regulation of iron import by regulation of transcription from RNA polymerase II promoter|regulation of iron ion import by regulation of transcription from RNA polymerase II promoter|regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter							2012-04-20T02:34:12Z			GO:1900393			biological_process											owl:Class	
GO:0106005	biolink:NamedThing	RNA 5'-cap (guanine-N7)-methylation	The process whereby a guanine in 5-cap is methylated at the N7 position of guanine.	got7fsn_ti							hjd	2017-04-07T19:19:57Z						biological_process											owl:Class	
GO:0030081	biolink:NamedThing	B800-820 antenna complex	Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.	got7fsn_ti	light harvesting complex III|LH3 complex													cellular_component											owl:Class	
GO:0048164	biolink:NamedThing	distinct antral spaces stage	The stage in oogenesis when the antral spaces become distinct and the first polar body forms.	got7fsn_ti	mammalian oogenesis stage 7													biological_process											owl:Class	
GO:0002918	biolink:NamedThing	negative regulation of peripheral B cell anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.	got7fsn_ti	downregulation of peripheral B cell anergy|down-regulation of peripheral B cell anergy|down regulation of peripheral B cell anergy|inhibition of peripheral B cell anergy													biological_process											owl:Class	
GO:0033210	biolink:NamedThing	leptin-mediated signaling pathway	A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.	got7fsn_ti	adipocytokine signaling pathway|leptin-mediated signalling pathway													biological_process											owl:Class	
GO:0044320	biolink:NamedThing	cellular response to leptin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism.	got7fsn_ti							jl	2010-07-14T02:21:32Z						biological_process											owl:Class	
GO:1990016	biolink:NamedThing	neck portion of tanycyte	Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.	got7fsn_ti	neck portion						pr	2012-12-19T15:17:17Z				NIF_Subcellular:sao901230115		cellular_component											owl:Class	
GO:1902047	biolink:NamedThing	polyamine transmembrane transport	The process in which a polyamine macromolecule is transported across a membrane.	got7fsn_ti	polyamine uptake|polyamine import						tb	2013-04-03T15:34:57Z			GO:1905122			biological_process											owl:Class	
GO:2000328	biolink:NamedThing	regulation of T-helper 17 cell lineage commitment	Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment.	got7fsn_ti	regulation of Th17 fate commitment|regulation of T-helper 17 cell fate commitment|regulation of Th17 cell lineage commitment						mah	2011-01-19T09:31:19Z						biological_process											owl:Class	
GO:1903963	biolink:NamedThing	arachidonate transport	The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	arachidonic acid transport						bhm	2015-02-25T16:06:14Z						biological_process											owl:Class	
GO:1905298	biolink:NamedThing	regulation of intestinal epithelial cell development	Any process that modulates the frequency, rate or extent of intestinal epithelial cell development.	got7fsn_ti							rph	2016-06-30T11:40:47Z						biological_process											owl:Class	
GO:1903190	biolink:NamedThing	glyoxal catabolic process	The chemical reactions and pathways resulting in the breakdown of glyoxal.	got7fsn_ti	glyoxal breakdown|glyoxal catabolism|glyoxal degradation						bf	2014-07-15T10:11:51Z						biological_process											owl:Class	
GO:0021661	biolink:NamedThing	rhombomere 4 morphogenesis	The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0051322	biolink:NamedThing	anaphase	The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Anaphase		biological_process											owl:Class	
GO:0002632	biolink:NamedThing	negative regulation of granuloma formation	Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.	got7fsn_ti	down-regulation of granuloma formation|downregulation of granuloma formation|down regulation of granuloma formation|inhibition of granuloma formation													biological_process											owl:Class	
GO:0044099	biolink:NamedThing	polar tube	A highly specialized structure unique to microsporidia that is required for host cell invasion. In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell.	got7fsn_ti							jl	2009-06-09T03:12:32Z						cellular_component											owl:Class	
GO:0030514	biolink:NamedThing	negative regulation of BMP signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.	got7fsn_ti	negative regulation of bone morphogenetic protein signalling pathway|negative regulation of decapentaplegic receptor signaling pathway|down-regulation of BMP signaling pathway|negative regulation of BMP receptor signaling pathway|downregulation of BMP signaling pathway|negative regulation of decapentaplegic receptor signalling pathway|down regulation of BMP signaling pathway|negative regulation of BMP signalling pathway|negative regulation of decapentaplegic signaling pathway|negative regulation of bone morphogenetic protein signaling pathway|inhibition of BMP signaling pathway						tb	2009-11-13T10:51:30Z			GO:0090099			biological_process											owl:Class	
GO:0080126	biolink:NamedThing	ovary septum development	The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s).	got7fsn_ti							dhl	2009-04-28T04:34:39Z						biological_process											owl:Class	
GO:0140510	biolink:NamedThing	mitotic nuclear bridge	A narrow constricted region of the nucleus that forms around the anaphase spindle during closed mitosis, and connects the main portions of the newly forming daughter nuclei.	got7fsn_ti	nuclear bridge						pg	2020-09-07T09:59:46Z						cellular_component											owl:Class	
GO:0097442	biolink:NamedThing	CA3 pyramidal cell dendrite	A dendrite of a hippocampal CA3 pyramidal cell.	got7fsn_ti							pr	2012-12-06T13:47:23Z				NIF_Subcellular:nlx_subcell_1005001		cellular_component											owl:Class	
CL:1001571	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001124	biolink:NamedThing	transcription elongation from bacterial-type RNA polymerase promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at a bacterial-type RNA polymerase promoter by the addition of ribonucleotides catalyzed by a bacterial-type RNA polymerase.	got7fsn_ti	RNA elongation from bacterial-type RNA polymerase promoter						krc	2010-12-06T03:46:27Z						biological_process											owl:Class	
GO:0032283	biolink:NamedThing	plastid acetate CoA-transferase complex	An acetate CoA-transferase complex located in the stroma of a plastid.	got7fsn_ti														cellular_component											owl:Class	
GO:0005740	biolink:NamedThing	mitochondrial envelope	The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.	got7fsn_ti														cellular_component											owl:Class	
GO:0101003	biolink:NamedThing	ficolin-1-rich granule membrane	The lipid bilayer surrounding a ficolin-1-rich granule.	got7fsn_ti							mec							cellular_component											owl:Class	
GO:1990318	biolink:NamedThing	collagen type XIX trimer	A collagen homotrimer of alpha1(XIX) chains; type XIX collagen triple helices localize to basement membrane zones in differentiating muscle cells.	got7fsn_ti							bhm	2014-03-14T16:05:57Z						cellular_component											owl:Class	
GO:0003357	biolink:NamedThing	noradrenergic neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.	got7fsn_ti	norepinephrine secreting neuron differentiation						dph	2009-12-03T10:34:30Z						biological_process											owl:Class	
GO:0002803	biolink:NamedThing	positive regulation of antibacterial peptide production	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production.	got7fsn_ti	stimulation of antibacterial peptide production|activation of antibacterial peptide production|up-regulation of antibacterial peptide production|up regulation of antibacterial peptide production|upregulation of antibacterial peptide production													biological_process											owl:Class	
GO:1903467	biolink:NamedThing	negative regulation of mitotic DNA replication initiation	Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.	got7fsn_ti	down regulation of DNA replication initiation involved in mitotic DNA replication|inhibition of DNA replication initiation involved in mitotic cell cycle DNA replication|down regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|inhibition of DNA replication initiation involved in mitotic DNA replication|downregulation of DNA replication initiation involved in mitotic cell cycle DNA replication|negative regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|down-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|downregulation of DNA replication initiation involved in mitotic DNA replication|down-regulation of DNA replication initiation involved in mitotic DNA replication						vw	2014-09-23T13:38:58Z						biological_process											owl:Class	
GO:1902969	biolink:NamedThing	mitotic DNA replication	Any nuclear DNA replication that is involved in a mitotic cell cycle.	got7fsn_ti	DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication involved in S phase involved in mitotic cell cycle|mitotic cell cycle DNA replication|DNA replication during S phase involved in mitotic cell cycle|nuclear cell cycle DNA replication involved in mitotic cell cycle|mitotic nuclear cell cycle DNA replication						jl	2014-05-06T15:03:03Z						biological_process											owl:Class	
GO:0006378	biolink:NamedThing	mRNA polyadenylation	The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.	got7fsn_ti	mRNA polyadenylylation|cleavage and polyadenylylation specificity factor activity													biological_process											owl:Class	
GO:0099173	biolink:NamedThing	postsynapse organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse.	got7fsn_ti	postsynapse development|postsynapse organisation|postsynapse morphogenesis|postsynapse organization and biogenesis													biological_process											owl:Class	
GO:0007526	biolink:NamedThing	larval somatic muscle development	The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0006270	biolink:NamedThing	DNA replication initiation	The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.	got7fsn_ti	DNA endoreduplication initiation|DNA-dependent DNA replication initiation|DNA re-replication initiation										GO:0042024			biological_process											owl:Class	
GO:1904866	biolink:NamedThing	ventral tegmental area development	The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure.	got7fsn_ti	ventral tegmental nucleus (tsai) development|ventral tegmental nucleus of tsai development|ventromedial mesencephalic tegmentum development|ventral tegmental area (Tsai) development|tegmentum ventrale development|ventral brain stem development|area tegmentalis ventralis development|ventral tegmental nucleus (Rioch) development|ventral tegmental area of tsai development|ventral tegmentum development|area tegmentalis ventralis (Tsai) development|a10a development|VTA development						bf	2015-12-17T14:44:18Z						biological_process											owl:Class	
GO:0030901	biolink:NamedThing	midbrain development	The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).	got7fsn_ti	mesencephalon development													biological_process											owl:Class	
GO:0061376	biolink:NamedThing	mammillotegmental axonal tract development	The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.	got7fsn_ti							dph	2010-11-09T09:09:29Z						biological_process											owl:Class	
GO:0062091	biolink:NamedThing	Ycf2/FtsHi complex	A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma.	got7fsn_ti	TIC complex associated chloroplast protein import motor						dph	2018-11-08T20:06:11Z						cellular_component											owl:Class	
GO:0035686	biolink:NamedThing	sperm fibrous sheath	A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.	got7fsn_ti	flagellum fibrous sheath|flagellar fibrous sheath						bf	2011-02-24T09:10:58Z						cellular_component											owl:Class	
GO:0043979	biolink:NamedThing	histone H2B-K5 acetylation	The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone.	got7fsn_ti	histone H2B acetylation at K5													biological_process											owl:Class	
GO:0042644	biolink:NamedThing	chloroplast nucleoid	The region of a chloroplast to which the DNA is confined.	got7fsn_ti														cellular_component											owl:Class	
GO:0044688	biolink:NamedThing	7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity	Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+.	got7fsn_ti							jl	2012-08-15T14:28:30Z						molecular_function											owl:Class	
GO:2001116	biolink:NamedThing	methanopterin-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a methanopterin.	got7fsn_ti	methanopterin biosynthesis						jl	2011-10-11T11:55:00Z						biological_process											owl:Class	
GO:0033120	biolink:NamedThing	positive regulation of RNA splicing	Any process that activates or increases the frequency, rate or extent of RNA splicing.	got7fsn_ti														biological_process											owl:Class	
GO:0070062	biolink:NamedThing	extracellular exosome	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.	got7fsn_ti	exosome|extracellular vesicular exosome													cellular_component											owl:Class	
GO:0071049	biolink:NamedThing	nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription	The process involved in retention of mRNAs that have incorrectly formed 3'-ends within the nucleus at the site of transcription.	got7fsn_ti							krc	2009-08-11T02:40:56Z						biological_process											owl:Class	
GO:0071031	biolink:NamedThing	nuclear mRNA surveillance of mRNA 3'-end processing	The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.	got7fsn_ti	nuclear mRNA quality control of mRNAs with aberrant 3'-ends|nuclear mRNA catabolic process of mRNA with aberrant 3'-ends						krc	2009-07-28T04:29:17Z						biological_process											owl:Class	
GO:0006407	biolink:NamedThing	rRNA export from nucleus	The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins.	got7fsn_ti	rRNA-nucleus export|rRNA transport from nucleus to cytoplasm|rRNA export from cell nucleus|rRNA export out of nucleus													biological_process											owl:Class	
GO:2000174	biolink:NamedThing	regulation of pro-T cell differentiation	Any process that modulates the frequency, rate or extent of pro-T cell differentiation.	got7fsn_ti	regulation of pro-T lymphocyte differentiation						mah	2010-10-11T10:24:30Z						biological_process											owl:Class	
GO:0099403	biolink:NamedThing	maintenance of mitotic sister chromatid cohesion, telomeric	The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.	got7fsn_ti	maintenance of mitotic sister chromatin cohesion at telomere|maintenance of sister chromatin cohesion at telomere at mitosis|maintenance of telomeric mitotic sister chromatin cohesion													biological_process											owl:Class	
GO:0099404	biolink:NamedThing	mitotic sister chromatid cohesion, telomeric	The cell cycle process in which telomeres of sister chromatids are joined during mitosis.	got7fsn_ti	mitotic sister chromatid cohesion at telomere|sister chromatid cohesion at telomere at mitosis|telomeric mitotic sister chromatin cohesion													biological_process											owl:Class	
GO:0031240	biolink:NamedThing	external side of cell outer membrane	The side of the outer membrane that is opposite to the side that faces the periplasm of the cell.	got7fsn_ti	external leaflet of cell outer membrane|external side of outer membrane				In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane.									cellular_component											owl:Class	
GO:0072229	biolink:NamedThing	metanephric proximal convoluted tubule development	The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.	got7fsn_ti							mah	2010-03-18T03:37:56Z						biological_process											owl:Class	
GO:0015111	biolink:NamedThing	iodide transmembrane transporter activity	Enables the transfer of iodide ions from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-209910|Reactome:R-HSA-5627870|Reactome:R-HSA-5627802		molecular_function											owl:Class	
GO:0015705	biolink:NamedThing	iodide transport	The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0046546	biolink:NamedThing	development of primary male sexual characteristics	The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0015161	biolink:NamedThing	lipid III floppase activity	Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.	got7fsn_ti	undecaprenol-pyrophosphate O-antigen flippase activity|capsule polysaccharide transporter activity|capsular polysaccharide transmembrane transporter activity											TC:2.A.66.2.3|TC:2.A.66.2.12		molecular_function											owl:Class	
GO:0015776	biolink:NamedThing	capsular polysaccharide transport	The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.	got7fsn_ti	capsular-polysaccharide transport|capsule polysaccharide transport													biological_process											owl:Class	
GO:0042281	biolink:NamedThing	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.	got7fsn_ti	dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase activity											EC:2.4.1.267|RHEA:30635|MetaCyc:RXN-5470		molecular_function											owl:Class	
GO:0033281	biolink:NamedThing	TAT protein transport complex	A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins.	got7fsn_ti	TAT protein secretion complex|TAT protein translocation system complex|Twin-arginine translocation complex													cellular_component											owl:Class	
GO:0032042	biolink:NamedThing	mitochondrial DNA metabolic process	The chemical reactions and pathways involving mitochondrial DNA.	got7fsn_ti	mtDNA metabolic process|mitochondrial DNA metabolism|mtDNA metabolism													biological_process											owl:Class	
GO:0097237	biolink:NamedThing	cellular response to toxic substance	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.	got7fsn_ti							pr	2012-02-02T12:23:31Z						biological_process											owl:Class	
GO:0005965	biolink:NamedThing	protein farnesyltransferase complex	A protein complex that possesses protein farnesyltransferase activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0004969	biolink:NamedThing	histamine receptor activity	Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	got7fsn_ti														molecular_function											owl:Class	
GO:0051381	biolink:NamedThing	histamine binding	Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	got7fsn_ti														molecular_function											owl:Class	
GO:0036021	biolink:NamedThing	endolysosome lumen	The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.	got7fsn_ti	endolysosomal lumen						bf	2011-10-13T04:32:31Z						cellular_component											owl:Class	
GO:0043245	biolink:NamedThing	extraorganismal space	The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms.	got7fsn_ti														cellular_component											owl:Class	
GO:0099581	biolink:NamedThing	ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential	Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.	got7fsn_ti	ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential|ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential													molecular_function											owl:Class	
GO:0044233	biolink:NamedThing	mitochondria-associated endoplasmic reticulum membrane	A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.	got7fsn_ti	ER-mitochondrion membrane contact site|Mitochondria-associated Membrane|MAM|mitochondria-associated ER membrane|endoplasmic reticulum-mitochondrion membrane contact site|mitochondria-associated membrane|mitochondria-endoplasmic reticulum (ER) contact						jl	2010-01-07T04:07:24Z						cellular_component											owl:Class	
CL:0000127	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0080187	biolink:NamedThing	floral organ senescence	An organ senescence that has as a participant a floral organ.	got7fsn_ti					Includes senescence of petals, sepals, anthers, and any other plant organ that is part of a flower. Floral organ senescence may follow pollination. In some flowers, the organs of the corolla abscise before they senesce.		dhl	2012-03-09T04:08:50Z						biological_process											owl:Class	
GO:0035803	biolink:NamedThing	egg coat formation	Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.	got7fsn_ti	ZP assembly|vitelline envelope formation|zona pellucida assembly|VE formation						bf	2011-04-19T01:48:43Z						biological_process											owl:Class	
GO:0110095	biolink:NamedThing	cellular detoxification of aldehyde	Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.	got7fsn_ti							kmv	2018-02-16T21:19:20Z						biological_process											owl:Class	
GO:0110096	biolink:NamedThing	cellular response to aldehyde	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.	got7fsn_ti							kmv	2018-02-16T21:29:18Z						biological_process											owl:Class	
GO:0007618	biolink:NamedThing	mating	The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.	got7fsn_ti														biological_process											owl:Class	
GO:0106174	biolink:NamedThing	phagolysosome vesicle lumen	The volume enclosed by the membrane of a phagolysosome.	got7fsn_ti							hjd	2019-02-11T19:10:46Z						cellular_component											owl:Class	
GO:0046821	biolink:NamedThing	extrachromosomal DNA	DNA structures that are not part of a chromosome.	got7fsn_ti												Wikipedia:Extrachromosomal_DNA		cellular_component											owl:Class	
GO:0007427	biolink:NamedThing	epithelial cell migration, open tracheal system	The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.	got7fsn_ti	tracheal epithelial cell migration|tracheal cell migration													biological_process											owl:Class	
GO:0002072	biolink:NamedThing	optic cup morphogenesis involved in camera-type eye development	The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.	got7fsn_ti	optic cup morphogenesis involved in camera-style eye development													biological_process											owl:Class	
GO:0090144	biolink:NamedThing	mitochondrial nucleoid organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined.	got7fsn_ti	mitochondrial nucleoid organisation						tb	2009-12-08T02:38:26Z						biological_process											owl:Class	
GO:0061332	biolink:NamedThing	Malpighian tubule bud morphogenesis	The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.	got7fsn_ti	Malpighian tubule formation						dph	2010-09-28T01:39:32Z						biological_process											owl:Class	
GO:1902379	biolink:NamedThing	chemoattractant activity involved in axon guidance	Any chemoattractant activity that is involved in axon guidance.	got7fsn_ti	chemoattractant activity involved in axon chemotaxis|chemoattractant activity involved in axon growth cone guidance|chemoattractant activity involved in axon pathfinding						bf	2013-09-02T13:49:35Z						molecular_function											owl:Class	
GO:0010380	biolink:NamedThing	regulation of chlorophyll biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.	got7fsn_ti														biological_process											owl:Class	
GO:0007576	biolink:NamedThing	nucleolar fragmentation	The cell aging process that results in the nucleolus breaking down into fragments.	got7fsn_ti	nucleolar size increase										GO:0046616			biological_process											owl:Class	
GO:0005674	biolink:NamedThing	transcription factor TFIIF complex	A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.	got7fsn_ti														cellular_component											owl:Class	
GO:0015247	biolink:NamedThing	aminophospholipid flippase activity	Enables the transfer of aminophospholipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.	got7fsn_ti	aminophospholipid transporter activity|aminophospholipid transmembrane transporter activity													molecular_function											owl:Class	
GO:0140331	biolink:NamedThing	aminophospholipid translocation	The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.	got7fsn_ti							pg	2019-05-10T13:46:34Z						biological_process											owl:Class	
GO:1905602	biolink:NamedThing	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.	got7fsn_ti	upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis involved in cholesterol transport|positive regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|upregulation of receptor-mediated endocytosis involved in cholesterol transport|up regulation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis involved in cholesterol transport|positive regulation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|activation of receptor-mediated endocytosis of LDL|up regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|activation of receptor-mediated endocytosis involved in cholesterol transport|activation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport						pr	2016-10-26T13:01:59Z						biological_process											owl:Class	
GO:0007552	biolink:NamedThing	metamorphosis	A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.	got7fsn_ti											GO:0046699|GO:0046698	Wikipedia:Metamorphosis		biological_process											owl:Class	
GO:0033096	biolink:NamedThing	amyloplast envelope	The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	got7fsn_ti														cellular_component											owl:Class	
GO:0004949	biolink:NamedThing	cannabinoid receptor activity	Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.	got7fsn_ti	endocannabinoid receptor activity|cannaboid receptor													molecular_function											owl:Class	
GO:0060715	biolink:NamedThing	syncytiotrophoblast cell differentiation involved in labyrinthine layer development	The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta.	got7fsn_ti							dph	2009-06-11T08:56:18Z						biological_process											owl:Class	
GO:0060029	biolink:NamedThing	convergent extension involved in organogenesis	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.	got7fsn_ti														biological_process											owl:Class	
GO:1902358	biolink:NamedThing	sulfate transmembrane transport	The directed movement of sulfate across a membrane.	got7fsn_ti							dph	2013-08-14T14:46:04Z						biological_process											owl:Class	
GO:0010318	biolink:NamedThing	pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex	Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.	got7fsn_ti	PFK complex, beta-subunit													cellular_component											owl:Class	
GO:1901021	biolink:NamedThing	positive regulation of calcium ion transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity.	got7fsn_ti	activation of calcium ion transmembrane transporter activity|up regulation of calcium ion transmembrane transporter activity|up-regulation of calcium ion transmembrane transporter activity|upregulation of calcium ion transmembrane transporter activity						rl	2012-06-15T07:54:40Z						biological_process											owl:Class	
GO:0016011	biolink:NamedThing	dystroglycan complex	A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.	got7fsn_ti														cellular_component											owl:Class	
GO:1990158	biolink:NamedThing	DnaB-DnaC-DnaT-PriA-PriB complex	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.	got7fsn_ti	DnaB-DnaC-DnaT-PriA-PriB preprimosome|phi-X174-type preprimosome						bhm	2013-08-02T11:52:55Z						cellular_component											owl:Class	
GO:0015232	biolink:NamedThing	heme transmembrane transporter activity	Enables the transfer of heme from one side of a membrane to the other.	got7fsn_ti	heme transporter activity|haem transporter activity	https://github.com/geneontology/go-ontology/issues/19472										Reactome:R-HSA-9661408|Reactome:R-HSA-917892|Reactome:R-HSA-917870		molecular_function											owl:Class	
GO:0015886	biolink:NamedThing	heme transport	The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	haem transport													biological_process											owl:Class	
GO:0030511	biolink:NamedThing	positive regulation of transforming growth factor beta receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.	got7fsn_ti	up-regulation of transforming growth factor beta receptor signaling pathway|positive regulation of TGF-beta receptor signaling pathway|upregulation of transforming growth factor beta receptor signaling pathway|activation of transforming growth factor beta receptor signaling pathway|positive regulation of TGFbeta receptor signaling pathway|stimulation of transforming growth factor beta receptor signaling pathway|up regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signalling pathway													biological_process											owl:Class	
GO:1901720	biolink:NamedThing	negative regulation of NMS complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.	got7fsn_ti	inhibition of KMN network assembly involved in chromosome segregation|down regulation of KMN network assembly involved in chromosome segregation|negative regulation of KMN network assembly involved in chromosome segregation|downregulation of NMS complex association involved in chromosome segregation|downregulation of KMN network assembly involved in chromosome segregation|down-regulation of KMN network assembly involved in chromosome segregation|down-regulation of NMS complex association involved in chromosome segregation|negative regulation of NMS complex assembly involved in kinetochore assembly|down-regulation of KMN complex interaction involved in chromosome segregation|down regulation of NMS complex association involved in chromosome segregation|downregulation of NMS complex interaction involved in chromosome segregation|negative regulation of KMN complex interaction involved in chromosome segregation|down regulation of KMN complex assembly involved in chromosome segregation|down-regulation of NMS complex interaction involved in chromosome segregation|negative regulation of NMS complex association involved in chromosome segregation|inhibition of NMS complex interaction involved in chromosome segregation|inhibition of NMS complex association involved in chromosome segregation|inhibition of KMN complex interaction involved in chromosome segregation|down regulation of NMS complex interaction involved in chromosome segregation|downregulation of KMN complex interaction involved in chromosome segregation						jl	2012-12-20T11:44:22Z						biological_process											owl:Class	
GO:2000261	biolink:NamedThing	negative regulation of blood coagulation, common pathway	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway.	got7fsn_ti							mah	2010-11-23T11:42:44Z						biological_process											owl:Class	
GO:0030720	biolink:NamedThing	oocyte localization involved in germarium-derived egg chamber formation	Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.	got7fsn_ti	oocyte localisation involved in germarium-derived egg chamber formation|oocyte localization during germarium-derived egg chamber formation|oogenesis, establishment and maintenance of oocyte localization|oogenesis, oocyte localization|establishment and maintenance of oocyte position during oogenesis|establishment and maintenance of oocyte localization in egg chamber|oocyte localization during oogenesis|oocyte positioning during oogenesis													biological_process											owl:Class	
GO:0048198	biolink:NamedThing	Golgi vesicle bud deformation and release	The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released.	got7fsn_ti	dictyosome vesicle bud deformation|Golgi-derived vesicle bud deformation and release													biological_process											owl:Class	
GO:0035015	biolink:NamedThing	elongation of arista core	The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.	got7fsn_ti														biological_process											owl:Class	
GO:1990505	biolink:NamedThing	mitotic DNA replication maintenance of fidelity	Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication.	got7fsn_ti	maintenance of fidelity involved in mitotic DNA replication|mitotic DNA replication maintenance of fidelity|maintenance of fidelity involved in mitotic cell cycle DNA replication						al	2014-10-01T14:09:05Z			GO:1990510			biological_process											owl:Class	
GO:0075045	biolink:NamedThing	regulation of formation by symbiont of haustorium for nutrient acquisition from host	Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0015437	biolink:NamedThing	lipopolysaccharide floppase activity	Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	lipopolysaccharide floppase activity (cytosolic to exoplasmic leaftlet)|lipopolysaccharide-transporting ATPase activity|LPS-transporting ATPase activity|ATP-dependent intramembrane lipopolysaccharide transporter activity|ATPase-coupled intramembrane lipopolysaccharide transporter activity													molecular_function											owl:Class	
GO:0016328	biolink:NamedThing	lateral plasma membrane	The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.	got7fsn_ti														cellular_component											owl:Class	
GO:0007495	biolink:NamedThing	visceral mesoderm-endoderm interaction involved in midgut development	The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut.	got7fsn_ti	visceral mesoderm/endoderm interaction													biological_process											owl:Class	
GO:0060676	biolink:NamedThing	ureteric bud formation	The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.	got7fsn_ti							dph	2009-06-02T01:47:23Z						biological_process											owl:Class	
GO:0000262	biolink:NamedThing	mitochondrial chromosome	A chromosome found in the mitochondrion of a eukaryotic cell.	got7fsn_ti	mtDNA|mitochondrial DNA|mitochondrial genome											NIF_Subcellular:sao1186327184		cellular_component											owl:Class	
GO:0042645	biolink:NamedThing	mitochondrial nucleoid	The region of a mitochondrion to which the DNA is confined.	got7fsn_ti														cellular_component											owl:Class	
GO:0001056	biolink:NamedThing	RNA polymerase III activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter						krc	2010-09-23T03:44:47Z				Reactome:R-HSA-1964482		molecular_function											owl:Class	
GO:0072674	biolink:NamedThing	multinuclear osteoclast differentiation	The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.	got7fsn_ti	multinuclear osteoclast morphogenesis|multinuclear osteoclast formation						mah	2011-02-22T02:10:38Z						biological_process											owl:Class	
GO:0031631	biolink:NamedThing	negative regulation of synaptic vesicle fusion to presynaptic active zone membrane	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.	got7fsn_ti	negative regulation of synaptic vesicle fusion to pre-synaptic membrane|inhibition of synaptic vesicle fusion to presynaptic membrane|downregulation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to presynaptic membrane|down regulation of synaptic vesicle fusion to presynaptic active zone membrane|downregulation of synaptic vesicle fusion to presynaptic active zone membrane|down regulation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to pre-synaptic active zone membrane|down-regulation of synaptic vesicle fusion to presynaptic membrane|down-regulation of synaptic vesicle fusion to presynaptic active zone membrane													biological_process											owl:Class	
GO:0015083	biolink:NamedThing	aluminum ion transmembrane transporter activity	Enables the transfer of aluminum (Al) ions from one side of a membrane to the other.	got7fsn_ti	aluminium resistance permease activity|aluminum resistance permease activity|aluminium ion transporter activity										GO:0015084			molecular_function											owl:Class	
GO:1902602	biolink:NamedThing	aluminum ion transmembrane transport	The process in which an aluminium ion is transported across a membrane.	got7fsn_ti	aluminium ion transmembrane transport|aluminium transmembrane transport|aluminum transmembrane transport						pr	2013-12-20T11:09:01Z						biological_process											owl:Class	
GO:0048368	biolink:NamedThing	lateral mesoderm development	The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.	got7fsn_ti	lateral plate mesoderm development													biological_process											owl:Class	
GO:0003334	biolink:NamedThing	keratinocyte development	The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-11-24T08:55:57Z						biological_process											owl:Class	
GO:0034117	biolink:NamedThing	erythrocyte aggregation	The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules.	got7fsn_ti	RBC aggregation|red blood cell aggregation													biological_process											owl:Class	
GO:0015205	biolink:NamedThing	nucleobase transmembrane transporter activity	Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.	got7fsn_ti											GO:0015392			molecular_function											owl:Class	
GO:0036365	biolink:NamedThing	transforming growth factor beta2 activation	The release of transforming growth factor beta 2 (TGF-beta2) from its latent state.	got7fsn_ti	TGFbeta 2 activation|TGF-beta 2 activation|TGFB2 activation						bf	2012-09-24T10:15:11Z						biological_process											owl:Class	
GO:2000520	biolink:NamedThing	regulation of immunological synapse formation	Any process that modulates the frequency, rate or extent of immunological synapse formation.	got7fsn_ti	regulation of formation of immunological synapse						ebc	2011-03-23T10:18:14Z						biological_process											owl:Class	
GO:0015541	biolink:NamedThing	secondary active cyanate transmembrane transporter activity	Enables the transfer of cyanate from one side of a membrane to the other.	got7fsn_ti	cyanate porter activity													molecular_function											owl:Class	
GO:0015704	biolink:NamedThing	cyanate transport	The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0016255	biolink:NamedThing	attachment of GPI anchor to protein	A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.	got7fsn_ti														biological_process											owl:Class	
UBERON:0001981	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000146	biolink:NamedThing	microfilament motor activity	A motor activity that generates movement along a microfilament, driven by ATP hydrolysis.	got7fsn_ti	myosin ATPase activity|actin filament motor activity|actin-dependent ATPase activity|actin-filament motor activity|actin-activated ATPase activity|muscle motor activity	https://github.com/geneontology/go-ontology/issues/20877									GO:0030898	EC:5.6.1.8|Reactome:R-HSA-432237|Reactome:R-HSA-9023171|Reactome:R-HSA-2316352		molecular_function											owl:Class	
GO:0016188	biolink:NamedThing	synaptic vesicle maturation	Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle.	got7fsn_ti														biological_process											owl:Class	
GO:0009534	biolink:NamedThing	chloroplast thylakoid	Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana.	got7fsn_ti														cellular_component											owl:Class	
GO:0099538	biolink:NamedThing	synaptic signaling via neuropeptide	Cell-cell signaling to or from a synapse, mediated by a peptide.	got7fsn_ti														biological_process											owl:Class	
GO:0000015	biolink:NamedThing	phosphopyruvate hydratase complex	A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.	got7fsn_ti	enolase complex													cellular_component											owl:Class	
GO:1903581	biolink:NamedThing	regulation of basophil degranulation	Any process that modulates the frequency, rate or extent of basophil degranulation.	got7fsn_ti							sl	2014-10-31T17:37:24Z						biological_process											owl:Class	
GO:0060340	biolink:NamedThing	positive regulation of type I interferon-mediated signaling pathway	Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.	got7fsn_ti	positive regulation of type I interferon-mediated signalling pathway													biological_process											owl:Class	
GO:0055015	biolink:NamedThing	ventricular cardiac muscle cell development	The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.	got7fsn_ti	ventricular cardiomyocyte development|ventricular heart muscle cell development													biological_process											owl:Class	
GO:0099547	biolink:NamedThing	regulation of translation at synapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating translation occurring at the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0010228	biolink:NamedThing	vegetative to reproductive phase transition of meristem	The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.	got7fsn_ti	floral evocation|flowering|transition from vegetative to reproductive phase													biological_process											owl:Class	
GO:0016530	biolink:NamedThing	metallochaperone activity	Binding to and delivering metal ions to a target protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0070236	biolink:NamedThing	negative regulation of activation-induced cell death of T cells	Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.	got7fsn_ti	inhibition of activation-induced cell death of T cells|negative regulation of activation-induced cell death of T-cells|downregulation of activation-induced cell death of T cells|negative regulation of activated T cell apoptosis|down regulation of activation-induced cell death of T cells|down-regulation of activation-induced cell death of T cells|negative regulation of antigen-driven apoptosis|negative regulation of AICD|negative regulation of activation-induced cell death of T-lymphocytes|negative regulation of activation-induced cell death of T lymphocytes													biological_process											owl:Class	
GO:0086060	biolink:NamedThing	voltage-gated sodium channel activity involved in AV node cell action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated sodium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in AV node cardiac muscle cell action potential						dph	2011-11-17T12:52:48Z						molecular_function											owl:Class	
GO:0021937	biolink:NamedThing	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation.	got7fsn_ti	Purkinje cell-granule cell precursor cell signalling involved in regulation of granule cell precursor cell proliferation													biological_process											owl:Class	
GO:0021940	biolink:NamedThing	positive regulation of cerebellar granule cell precursor proliferation	The process that activates or increases the rate or extent of granule cell precursor proliferation.	got7fsn_ti	up-regulation of granule cell precursor proliferation|activation of granule cell precursor proliferation|upregulation of granule cell precursor proliferation|up regulation of granule cell precursor proliferation|stimulation of granule cell precursor proliferation													biological_process											owl:Class	
GO:0098907	biolink:NamedThing	regulation of SA node cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti	regulation of sinoatrial node cardiac muscle cell action potential|regulation of SA node cardiac muscle cell action potential|regulation of sinus node cardiac muscle cell action potential|regulation of SAN cardiac muscle cell action potential						tb	2011-11-10T08:50:15Z						biological_process											owl:Class	
GO:0021758	biolink:NamedThing	putamen development	The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.	got7fsn_ti														biological_process											owl:Class	
GO:0003978	biolink:NamedThing	UDP-glucose 4-epimerase activity	Catalysis of the reaction: UDP-glucose = UDP-galactose.	got7fsn_ti	uridine diphospho-galactose-4-epimerase activity|uridine diphosphate glucose 4-epimerase activity|UDPgalactose 4-epimerase activity|UDP-glucose epimerase activity|uridine diphosphate galactose 4-epimerase activity|UDPglucose 4-epimerase activity|uridine diphosphoglucose 4-epimerase activity|UDP-D-galactose 4-epimerase activity|galactowaldenase activity|uridine diphosphoglucose epimerase activity|4-epimerase activity|UDPG-4-epimerase activity|UDP-galactose 4-epimerase activity											RHEA:22168|EC:5.1.3.2|Reactome:R-HSA-70369|MetaCyc:UDPGLUCEPIM-RXN|Reactome:R-HSA-5610036		molecular_function											owl:Class	
GO:0034744	biolink:NamedThing	APC-IQGAP1-Cdc42 complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.	got7fsn_ti					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0060770	biolink:NamedThing	negative regulation of epithelial cell proliferation involved in prostate gland development	Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.	got7fsn_ti							dph	2009-07-08T07:40:27Z						biological_process											owl:Class	
GO:0021609	biolink:NamedThing	accessory nerve structural organization	The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	got7fsn_ti	CN XI structural organization|accessory nerve structural organisation													biological_process											owl:Class	
GO:0043998	biolink:NamedThing	H2A histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.	got7fsn_ti	H2A histone lysine N-acetyltransferase activity													molecular_function											owl:Class	
GO:0002004	biolink:NamedThing	secretion of vasopressin involved in fast regulation of systemic arterial blood pressure	The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure.	got7fsn_ti	secretion of vasopressin during fast regulation of systemic arterial blood pressure|secretion of vasopressin during fast control of blood pressure													biological_process											owl:Class	
GO:1990262	biolink:NamedThing	anti-Mullerian hormone signaling pathway	A series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti					An example of this is Amhr2 in M. musculus (Q8K592) a receptor for anti-mullerian hormone, described in PMID:23624077.		hjd	2014-01-08T20:42:09Z						biological_process											owl:Class	
GO:0001516	biolink:NamedThing	prostaglandin biosynthetic process	The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.	got7fsn_ti	prostaglandin formation|prostaglandin anabolism|prostaglandin synthesis|prostaglandin biosynthesis													biological_process											owl:Class	
GO:0060775	biolink:NamedThing	planar cell polarity pathway involved in gastrula mediolateral intercalation	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation.	got7fsn_ti							dph	2009-07-25T06:52:50Z						biological_process											owl:Class	
GO:0090245	biolink:NamedThing	axis elongation involved in somitogenesis	The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis.	got7fsn_ti							tb	2010-01-22T10:54:29Z						biological_process											owl:Class	
GO:0019172	biolink:NamedThing	glyoxalase III activity	Catalysis of the reaction: methylglyoxal + H2O = D-lactate.	got7fsn_ti	(R)-lactate hydro-lyase|glutathione-independent glyoxalase activity|D-lactate dehydratase				Note that this term was reinstated from obsolete. Also note that this enzymatic activity converts methylglyoxal to D-lactate in a single glutathione (GSH)-independent step. The other known route for this conversion is the two-step GSH-dependent pathway catalyzed by EC:4.4.1.5 (lactoylglutathione lyase) and EC:3.1.2.6 (hydroxyacylglutathione hydrolase).							MetaCyc:GLYOXIII-RXN|RHEA:27754|EC:4.2.1.130		molecular_function											owl:Class	
GO:0072269	biolink:NamedThing	metanephric long descending thin limb development	The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.	got7fsn_ti							mah	2010-03-30T03:12:05Z						biological_process											owl:Class	
GO:0031260	biolink:NamedThing	pseudopodium membrane	The portion of the plasma membrane surrounding a pseudopodium.	got7fsn_ti														cellular_component											owl:Class	
GO:0031283	biolink:NamedThing	negative regulation of guanylate cyclase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.	got7fsn_ti	downregulation of guanylate cyclase activity|down-regulation of guanylate cyclase activity|inhibition of guanylate cyclase activity|down regulation of guanylate cyclase activity													biological_process											owl:Class	
GO:0010443	biolink:NamedThing	meristemoid mother cell division	The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC.	got7fsn_ti	meristemoid division													biological_process											owl:Class	
GO:0009942	biolink:NamedThing	longitudinal axis specification	The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.	got7fsn_ti	longitudinal axis determination|apical-basal pattern specification													biological_process											owl:Class	
GO:0034107	biolink:NamedThing	negative regulation of erythrocyte clearance	Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance.	got7fsn_ti	negative regulation of neocytolysis|negative regulation of red blood cell clearance|negative regulation of RBC clearance													biological_process											owl:Class	
GO:0031617	biolink:NamedThing	NMS complex	A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes.	got7fsn_ti	KMN kinetochore network|Ndc80-MIND-Spc7 complex|KNL-1-Mis12-Ndc80													cellular_component											owl:Class	
GO:0005628	biolink:NamedThing	prospore membrane	The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.	got7fsn_ti	ascospore-type prospore membrane|forespore membrane|FSM													cellular_component											owl:Class	
GO:0062238	biolink:NamedThing	Smp focus	A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I.	got7fsn_ti	Smp dot						dph	2020-04-20T14:23:04Z						cellular_component											owl:Class	
GO:0042581	biolink:NamedThing	specific granule	Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.	got7fsn_ti	secondary granule											Wikipedia:Specific_granule		cellular_component											owl:Class	
GO:0102973	biolink:NamedThing	norsolorinate anthrone synthase activity	Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein].	got7fsn_ti	norsolorinic acid synthase											MetaCyc:RXN-9479|EC:2.3.1.221|RHEA:35179		molecular_function											owl:Class	
GO:0045698	biolink:NamedThing	negative regulation of synergid differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation.	got7fsn_ti	downregulation of synergid differentiation|down regulation of synergid differentiation|negative regulation of synergid cell differentiation|down-regulation of synergid differentiation|inhibition of synergid differentiation													biological_process											owl:Class	
GO:0043281	biolink:NamedThing	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis.	got7fsn_ti	regulation of caspase activity|regulation of caspase activation										GO:0043026			biological_process											owl:Class	
GO:1900740	biolink:NamedThing	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.	got7fsn_ti	up regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|up-regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|upregulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|up regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|upregulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|activation of protein insertion into mitochondrial membrane involved in induction of apoptosis|up-regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|activation of protein insertion into mitochondrion membrane during induction of apoptosis|upregulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|upregulation of protein insertion into mitochondrion membrane during induction of apoptosis|up regulation of protein insertion into mitochondrial membrane during induction of apoptosis|up regulation of protein insertion into mitochondrion membrane during induction of apoptosis|positive regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|up regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|positive regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|activation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|positive regulation of protein insertion into mitochondrial membrane during induction of apoptosis|activation of protein insertion into mitochondrial membrane during induction of apoptosis|positive regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|upregulation of protein insertion into mitochondrial membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane during induction of apoptosis|activation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway						pr	2012-05-28T02:28:40Z						biological_process											owl:Class	
GO:0070986	biolink:NamedThing	left/right axis specification	The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).	got7fsn_ti	left-right axis specification|left/right axis determination						mah	2009-10-29T01:43:34Z						biological_process											owl:Class	
GO:0035216	biolink:NamedThing	haltere disc development	Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.	got7fsn_ti														biological_process											owl:Class	
GO:0001945	biolink:NamedThing	lymph vessel development	The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:1904443	biolink:NamedThing	positive regulation of thyroid gland epithelial cell proliferation	Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation.	got7fsn_ti	up regulation of thyroid gland epithelial cell proliferation|positive regulation of Hurthle cell proliferation|upregulation of thyroid follicular cell proliferation|activation of thyroid follicular cell proliferation|activation of Hurthle cell proliferation|up-regulation of thyroid follicular cell proliferation|up-regulation of Hurthle cell proliferation|activation of thyroid gland epithelial cell proliferation|up-regulation of thyroid gland epithelial cell proliferation|up regulation of thyroid follicular cell proliferation|upregulation of thyroid gland epithelial cell proliferation|up regulation of Hurthle cell proliferation|upregulation of Hurthle cell proliferation|positive regulation of thyroid follicular cell proliferation						sl	2015-07-06T15:41:21Z						biological_process											owl:Class	
GO:0098846	biolink:NamedThing	podocyte foot	A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms.	got7fsn_ti	podocyte foot process|pedicel|secondary podocyte projection											Wikipedia:Podocyte		cellular_component											owl:Class	
CL:0000653	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042961	biolink:NamedThing	ATPase-coupled antimonite transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out).	got7fsn_ti	ATP-dependent antimonite transporter activity|antimonite-transporting ATPase activity													molecular_function											owl:Class	
GO:0015699	biolink:NamedThing	antimonite transport	The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0010096	biolink:NamedThing	specification of sepal identity	The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0048453	biolink:NamedThing	sepal formation	The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti											GO:0048423			biological_process											owl:Class	
GO:0015110	biolink:NamedThing	cyanate transmembrane transporter activity	Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0034591	biolink:NamedThing	rhoptry lumen	The volume enclosed by the rhoptry membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0009736	biolink:NamedThing	cytokinin-activated signaling pathway	A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	cytokinin mediated signalling|cytokinin signaling|cytokinin mediated signaling pathway													biological_process											owl:Class	
GO:0071368	biolink:NamedThing	cellular response to cytokinin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.	got7fsn_ti							mah	2009-12-11T03:13:47Z						biological_process											owl:Class	
GO:0002645	biolink:NamedThing	positive regulation of tolerance induction	Any process that activates or increases the frequency, rate, or extent of tolerance induction.	got7fsn_ti	up-regulation of tolerance induction|up regulation of tolerance induction|upregulation of tolerance induction|activation of tolerance induction|stimulation of tolerance induction													biological_process											owl:Class	
GO:0071030	biolink:NamedThing	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing	The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.	got7fsn_ti	nuclear mRNA quality control of incorrectly spliced pre-mRNA|nuclear RNA catabolic process of incorrectly spliced pre-mRNA						krc	2009-07-28T04:24:04Z						biological_process											owl:Class	
GO:1903690	biolink:NamedThing	negative regulation of wound healing, spreading of epidermal cells	Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells.	got7fsn_ti	downregulation of wound healing, spreading of epidermal cells|inhibition of wound healing, spreading of epidermal cells|down regulation of wound healing, spreading of epidermal cells|down-regulation of wound healing, spreading of epidermal cells						als	2014-12-01T15:54:27Z						biological_process											owl:Class	
GO:1990233	biolink:NamedThing	intramolecular phosphotransferase complex	A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule.	got7fsn_ti							bhm	2013-11-12T13:10:12Z						cellular_component											owl:Class	
GO:0060011	biolink:NamedThing	Sertoli cell proliferation	The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.	got7fsn_ti														biological_process											owl:Class	
GO:0016342	biolink:NamedThing	catenin complex	Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton.	got7fsn_ti														cellular_component											owl:Class	
GO:2000555	biolink:NamedThing	negative regulation of T-helper 1 cell cytokine production	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production.	got7fsn_ti	negative regulation of Th1 cell cytokine production						ebc	2011-04-03T07:35:51Z						biological_process											owl:Class	
GO:0038140	biolink:NamedThing	ERBB4-ERBB3 complex	A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission.	got7fsn_ti	ERBB4:ERBB3 heterodimer|ERBB3-ERBB4 complex						bf	2012-03-30T02:04:16Z						cellular_component											owl:Class	
GO:0071315	biolink:NamedThing	cellular response to morphine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.	got7fsn_ti							mah	2009-12-10T04:53:46Z						biological_process											owl:Class	
GO:0010009	biolink:NamedThing	cytoplasmic side of endosome membrane	The side (leaflet) of the endosome membrane that faces the cytoplasm.	got7fsn_ti	external side of endosome membrane|external leaflet of endosome membrane													cellular_component											owl:Class	
GO:0060526	biolink:NamedThing	prostate glandular acinus morphogenesis	The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.	got7fsn_ti														biological_process											owl:Class	
GO:0051032	biolink:NamedThing	nucleic acid transmembrane transporter activity	Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.	got7fsn_ti														molecular_function											owl:Class	
GO:0050657	biolink:NamedThing	nucleic acid transport	The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1901309	biolink:NamedThing	negative regulation of sterol regulatory element binding protein cleavage	Any process that stops, prevents or reduces the frequency, rate or extent of sterol regulatory element binding protein cleavage.	got7fsn_ti	down regulation of sterol regulatory element binding protein cleavage|inhibition of SREBP processing|inhibition of sterol regulatory element binding protein cleavage|inhibition of SREBP cleavage|negative regulation of SREBP cleavage|downregulation of sterol regulatory element binding protein cleavage|downregulation of SREBP cleavage|down-regulation of sterol regulatory element binding protein cleavage|down regulation of SREBP cleavage|down-regulation of SREBP cleavage						bf	2012-08-21T16:43:32Z						biological_process											owl:Class	
GO:0001835	biolink:NamedThing	blastocyst hatching	The hatching of the cellular blastocyst from the zona pellucida.	got7fsn_ti					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, zona pellucida ; EMAP:22' and 'TS5, embryo ; EMAP:23'.									biological_process											owl:Class	
GO:0001824	biolink:NamedThing	blastocyst development	The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.	got7fsn_ti					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'.									biological_process											owl:Class	
GO:0099038	biolink:NamedThing	ceramide floppase activity	Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	ATP-dependent ceramide transporter activity|ceramide-translocating ATPase activity|ATPase-coupled ceramide transporter activity|ceramide floppase activity (cytosolic to exoplasmic leaftlet)													molecular_function											owl:Class	
GO:0099040	biolink:NamedThing	ceramide translocation	The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet.	got7fsn_ti														biological_process											owl:Class	
GO:0035808	biolink:NamedThing	meiotic recombination initiation complex	A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins.	got7fsn_ti							bf	2011-04-20T11:52:50Z						cellular_component											owl:Class	
GO:1905701	biolink:NamedThing	positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	upregulation of drug transmembrane export|positive regulation of xenobiotic transmembrane export|up-regulation of drug transmembrane export|up regulation of drug transmembrane export|positive regulation of drug transmembrane export|activation of drug transmembrane export	https://github.com/geneontology/go-ontology/issues/19460|https://github.com/geneontology/go-ontology/issues/17083					sl	2016-11-15T16:46:44Z						biological_process											owl:Class	
GO:0015100	biolink:NamedThing	vanadium ion transmembrane transporter activity	Enables the transfer of vanadium (V) ions from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015676	biolink:NamedThing	vanadium ion transport	The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0009542	biolink:NamedThing	granum	Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis.	got7fsn_ti														cellular_component											owl:Class	
GO:1901219	biolink:NamedThing	regulation of cardiac chamber morphogenesis	Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.	got7fsn_ti	regulation of heart chamber morphogenesis						rl	2012-08-06T17:59:11Z						biological_process											owl:Class	
GO:0008509	biolink:NamedThing	anion transmembrane transporter activity	Enables the transfer of a negatively charged ion from one side of a membrane to the other.	got7fsn_ti	anion transporter activity											Reactome:R-HSA-166214		molecular_function											owl:Class	
GO:0006127	biolink:NamedThing	glycerophosphate shuttle	The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.	got7fsn_ti												MetaCyc:PWY-6118		biological_process											owl:Class	
GO:0005463	biolink:NamedThing	UDP-N-acetylgalactosamine transmembrane transporter activity	Enables the transfer of a N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0015789	biolink:NamedThing	UDP-N-acetylgalactosamine transmembrane transport	The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-N-acetylgalactosamine transport													biological_process											owl:Class	
GO:1901396	biolink:NamedThing	negative regulation of transforming growth factor beta2 activation	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation.	got7fsn_ti	inhibition of TGFB2 activation|downregulation of TGFB2 activation|inhibition of TGF-beta 2 activation|downregulation of transforming growth factor beta2 activation|down-regulation of TGFB2 activation|down regulation of TGFbeta 2 activation|inhibition of transforming growth factor beta2 activation|down-regulation of TGF-beta 2 activation|inhibition of TGFbeta 2 activation|down-regulation of transforming growth factor beta2 activation|negative regulation of TGFbeta 2 activation|negative regulation of TGFB2 activation|negative regulation of TGF-beta 2 activation|down regulation of TGF-beta 2 activation|down-regulation of TGFbeta 2 activation|downregulation of TGF-beta 2 activation|downregulation of TGFbeta 2 activation|down regulation of TGFB2 activation|down regulation of transforming growth factor beta2 activation						bf	2012-10-01T10:47:59Z						biological_process											owl:Class	
GO:0070268	biolink:NamedThing	cornification	A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).	got7fsn_ti														biological_process											owl:Class	
GO:0000794	biolink:NamedThing	condensed nuclear chromosome	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.	got7fsn_ti	meiotic chromosome|nuclear mitotic chromosome				Note that this term and its children can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes a 'closed mitosis' in which the nuclear envelope does not break down during mitosis and for gene products that localize to a meiotic chromosome.									cellular_component											owl:Class	
GO:0006272	biolink:NamedThing	leading strand elongation	The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12633												biological_process											owl:Class	
GO:1902942	biolink:NamedThing	negative regulation of voltage-gated chloride channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity.	got7fsn_ti	downregulation of voltage-dependent chloride channel activity|down-regulation of voltage-gated chloride channel activity|downregulation of voltage gated chloride channel activity|inhibition of voltage gated chloride channel activity|negative regulation of voltage gated chloride channel activity|down regulation of voltage-gated chloride channel activity|inhibition of voltage-dependent chloride channel activity|downregulation of voltage-gated chloride channel activity|down regulation of voltage-dependent chloride channel activity|negative regulation of voltage-dependent chloride channel activity|inhibition of voltage-gated chloride channel activity|down-regulation of voltage gated chloride channel activity|down regulation of voltage gated chloride channel activity|down-regulation of voltage-dependent chloride channel activity						als	2014-04-28T08:55:37Z						biological_process											owl:Class	
GO:0008200	biolink:NamedThing	ion channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of an ion channel.	got7fsn_ti														molecular_function											owl:Class	
GO:0015441	biolink:NamedThing	ABC-type beta-glucan transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out).	got7fsn_ti	beta-glucan-transporting ATPase activity|ATP-dependent beta-glucan transporter activity|ABC-type beta-glucan transporter|ATPase-coupled beta-glucan transporter activity|beta-glucan ABC transporter											EC:7.5.2.3|RHEA:18453|MetaCyc:3.6.3.42-RXN		molecular_function											owl:Class	
GO:0015775	biolink:NamedThing	beta-glucan transport	The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.	got7fsn_ti														biological_process											owl:Class	
GO:0034451	biolink:NamedThing	centriolar satellite	A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0022897	biolink:NamedThing	proton-dependent peptide secondary active transmembrane transporter activity	Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.	got7fsn_ti	hydrogen/oligopeptide symporter													molecular_function											owl:Class	
GO:0038132	biolink:NamedThing	neuregulin binding	Binding to a neuregulin, a member of the EGF family of growth factors.	got7fsn_ti							bf	2012-03-30T10:59:56Z						molecular_function											owl:Class	
GO:1990008	biolink:NamedThing	neurosecretory vesicle	A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus.	got7fsn_ti							pr	2012-12-12T09:56:14Z				NIF_Subcellular:sao2031592629		cellular_component											owl:Class	
CL:0000165	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008385	biolink:NamedThing	IkappaB kinase complex	A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.	got7fsn_ti	IKK complex|heterotrimeric IKK complex|trimeric IKK complex													cellular_component											owl:Class	
GO:0046798	biolink:NamedThing	viral portal complex	A multimeric ring of proteins through which the DNA enters and exits the viral capsid.	got7fsn_ti														cellular_component											owl:Class	
GO:0070154	biolink:NamedThing	mitochondrial lysyl-tRNA aminoacylation	The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:1904888	biolink:NamedThing	cranial skeletal system development	The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.	got7fsn_ti	craniofacial development|osteocranium development|cranial skeleton development|cranium development						bf	2016-01-07T13:45:06Z						biological_process											owl:Class	
CHEBI:15361	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060939	biolink:NamedThing	epicardium-derived cardiac fibroblast cell development	The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T01:29:19Z						biological_process											owl:Class	
GO:1901019	biolink:NamedThing	regulation of calcium ion transmembrane transporter activity	Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.	got7fsn_ti							rl	2012-06-15T07:54:12Z						biological_process											owl:Class	
GO:0099185	biolink:NamedThing	postsynaptic intermediate filament cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of  cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton.	got7fsn_ti							dos	2017-12-20T13:47:30Z						biological_process											owl:Class	
GO:1990295	biolink:NamedThing	post-anaphase microtubule array	A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center.	got7fsn_ti	PAA|post-anaphase array				The best-characterized example is found in the fission yeast Schizosaccharomyces pombe. The eMTOC is cortical, but the post-anaphase array microtubules are not exclusively cortical.		mah	2014-02-20T13:54:23Z						cellular_component											owl:Class	
GO:0009508	biolink:NamedThing	plastid chromosome	A circular DNA molecule containing plastid encoded genes.	got7fsn_ti														cellular_component											owl:Class	
GO:0042646	biolink:NamedThing	plastid nucleoid	The region of a plastid to which the DNA is confined.	got7fsn_ti														cellular_component											owl:Class	
GO:0015128	biolink:NamedThing	gluconate transmembrane transporter activity	Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose.	got7fsn_ti	L-idonate/D-gluconate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0035429	biolink:NamedThing	gluconate transmembrane transport	The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose.	got7fsn_ti	gluconate transport|gluconate membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T10:33:46Z			GO:0015725			biological_process											owl:Class	
GO:0061155	biolink:NamedThing	pulmonary artery endothelial tube morphogenesis	The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.	got7fsn_ti							dph	2010-06-15T09:09:04Z						biological_process											owl:Class	
GO:1902909	biolink:NamedThing	negative regulation of melanosome transport	Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport.	got7fsn_ti	down regulation of melanosome transport|inhibition of melanosome transport|down-regulation of melanosome transport|downregulation of melanosome transport						als	2014-04-17T11:40:28Z						biological_process											owl:Class	
GO:0006913	biolink:NamedThing	nucleocytoplasmic transport	The directed movement of molecules between the nucleus and the cytoplasm.	got7fsn_ti	nucleocytoplasmic shuttling				Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed.						GO:0000063			biological_process											owl:Class	
GO:1990378	biolink:NamedThing	upstream stimulatory factor complex	A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters.	got7fsn_ti	USF1 homodimer|USF1-USF2 heterodimer|USF2 homodimer|USF complex				An example of this is USF1 in human (UniProt symbol P22415) in PMID:8576131 (inferred from direct assay).		bhm	2014-05-07T15:41:42Z						cellular_component											owl:Class	
GO:0031927	biolink:NamedThing	pyridoxamine transmembrane transporter activity	Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:1903091	biolink:NamedThing	pyridoxamine transmembrane transport	The process in which pyridoxamine is transported across a membrane.	got7fsn_ti							al	2014-06-03T10:41:20Z						biological_process											owl:Class	
GO:0043671	biolink:NamedThing	endexine	The inner part of the exine, which stains.	got7fsn_ti					Note that endexine is distinguished on staining properties; compare with 'sexine ; GO:0043673'. See also 'ectexine ; GO:0043669'.									cellular_component											owl:Class	
GO:0016559	biolink:NamedThing	peroxisome fission	The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.	got7fsn_ti	peroxisome proliferation|peroxisome division													biological_process											owl:Class	
GO:0022027	biolink:NamedThing	interkinetic nuclear migration	The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle.	got7fsn_ti														biological_process											owl:Class	
GO:1903682	biolink:NamedThing	negative regulation of epithelial cell-cell adhesion involved in epithelium migration	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.	got7fsn_ti	inhibition of epithelial cell-cell adhesion involved in epithelium migration|downregulation of epithelial cell-cell adhesion involved in epithelium migration|down regulation of epithelial cell-cell adhesion involved in epithelium migration|down-regulation of epithelial cell-cell adhesion involved in epithelium migration						als	2014-12-01T13:25:14Z						biological_process											owl:Class	
GO:0008515	biolink:NamedThing	sucrose transmembrane transporter activity	Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.	got7fsn_ti	sucrose permease (PTS) activity|sucrose permease activity										GO:0019188			molecular_function											owl:Class	
GO:0015774	biolink:NamedThing	polysaccharide transport	The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	got7fsn_ti														biological_process											owl:Class	
GO:0042945	biolink:NamedThing	D-serine transmembrane transporter activity	Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid.	got7fsn_ti	D-serine transporter activity|D-serine permease activity													molecular_function											owl:Class	
GO:0042942	biolink:NamedThing	D-serine transport	The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0002932	biolink:NamedThing	tendon sheath development	The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.	got7fsn_ti							hjd	2012-04-23T02:11:22Z						biological_process											owl:Class	
GO:0043319	biolink:NamedThing	positive regulation of cytotoxic T cell degranulation	Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation.	got7fsn_ti	positive regulation of cytotoxic T lymphocyte degranulation|positive regulation of cytotoxic T cell granule exocytosis|activation of cytotoxic T cell degranulation|stimulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T lymphocyte granule exocytosis|up-regulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T-lymphocyte granule exocytosis|positive regulation of cytotoxic T-lymphocyte degranulation|up regulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T-cell granule exocytosis|upregulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T-cell degranulation													biological_process											owl:Class	
GO:1990758	biolink:NamedThing	mitotic sister chromatid biorientation	The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression.	got7fsn_ti							vw	2015-06-02T12:36:17Z						biological_process											owl:Class	
GO:0051010	biolink:NamedThing	microtubule plus-end binding	Binding to the plus end of a microtubule.	got7fsn_ti														molecular_function											owl:Class	
GO:0098904	biolink:NamedThing	regulation of AV node cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti	regulation of AV node cardiac muscle cell action potential|regulation of atrioventricular node cardiac muscle cell action potential						tb	2011-11-10T08:58:56Z						biological_process											owl:Class	
GO:1903752	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.	got7fsn_ti	upregulation of intrinsic apoptotic signaling pathway in response to H2O2|up-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|up regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|up regulation of H2O2-induced intrinsic apoptotic signaling pathway|activation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|positive regulation of H2O2-induced intrinsic apoptotic signaling pathway|positive regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|upregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|positive regulation of intrinsic apoptotic signaling pathway in response to H2O2|upregulation of H2O2-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|activation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|up-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|up-regulation of intrinsic apoptotic signaling pathway in response to H2O2|up regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|up regulation of intrinsic apoptotic signaling pathway in response to H2O2|activation of H2O2-induced intrinsic apoptotic signaling pathway|up-regulation of H2O2-induced intrinsic apoptotic signaling pathway|activation of intrinsic apoptotic signaling pathway in response to H2O2						krc	2014-12-12T23:04:46Z						biological_process											owl:Class	
GO:0062001	biolink:NamedThing	negative regulation of cardiac endothelial to mesenchymal transition	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition.	got7fsn_ti							dph	2018-02-16T16:36:48Z						biological_process											owl:Class	
CHEBI:16480	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010826	biolink:NamedThing	negative regulation of centrosome duplication	Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	got7fsn_ti														biological_process											owl:Class	
GO:1904415	biolink:NamedThing	regulation of xenophagy	Any process that modulates the frequency, rate or extent of xenophagy.	got7fsn_ti					An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype).		pad	2015-06-29T12:30:47Z						biological_process											owl:Class	
GO:1900104	biolink:NamedThing	regulation of hyaluranon cable assembly	Any process that modulates the frequency, rate or extent of hyaluranon cable assembly.	got7fsn_ti	regulation of HA cable assembly						yaf	2012-02-16T01:00:41Z						biological_process											owl:Class	
GO:0046551	biolink:NamedThing	retinal cone cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye.	got7fsn_ti														biological_process											owl:Class	
GO:1901995	biolink:NamedThing	positive regulation of meiotic cell cycle phase transition	Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition.	got7fsn_ti	positive regulation of cell cycle transition|up-regulation of meiotic cell cycle phase transition|up regulation of cell cycle transition|activation of meiotic cell cycle phase transition|upregulation of meiotic cell cycle phase transition|up-regulation of cell cycle transition|activation of cell cycle transition|up regulation of meiotic cell cycle phase transition|upregulation of cell cycle transition						jl	2013-03-19T16:15:08Z						biological_process											owl:Class	
GO:0004707	biolink:NamedThing	MAP kinase activity	Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.	got7fsn_ti	MBP kinase II activity|SAPK|ERK|myelin basic protein kinase activity|MBP kinase I activity|MAP kinase 2 activity|ERK2|MAPK|mitogen activated kinase activity|MAP kinase 1 activity|stress-activated protein kinase activity|ATP:protein phosphotransferase (MAPKK-activated) activity|SAP kinase activity|extracellular signal-regulated kinase activity|ERK1|mitogen-activated protein kinase activity|stress-activated kinase activity										GO:0016908|GO:0016909|GO:0008339|GO:0008338	Reactome:R-HSA-5654562|Reactome:R-HSA-451366|MetaCyc:2.7.11.24-RXN|Reactome:R-HSA-5654566|Reactome:R-HSA-198733|Reactome:R-HSA-9626832|Reactome:R-HSA-111898|Reactome:R-HSA-5654560|Reactome:R-HSA-5654565|EC:2.7.11.24|Reactome:R-HSA-445079|KEGG_REACTION:R00162|Reactome:R-HSA-73722		molecular_function											owl:Class	
GO:0031566	biolink:NamedThing	actomyosin contractile ring maintenance	The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle.	got7fsn_ti	contractile ring maintenance involved in cell cycle cytokinesis|cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle													biological_process											owl:Class	
GO:0001546	biolink:NamedThing	preantral ovarian follicle growth	Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.	got7fsn_ti														biological_process											owl:Class	
GO:0021656	biolink:NamedThing	rhombomere 2 structural organization	The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti	rhombomere 2 structural organisation													biological_process											owl:Class	
GO:1990101	biolink:NamedThing	DnaA-oriC complex	A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle.	got7fsn_ti	DnaA-DNA complex						bhm	2013-05-14T12:07:04Z						cellular_component											owl:Class	
GO:1900162	biolink:NamedThing	negative regulation of phospholipid scramblase activity	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity.	got7fsn_ti	down-regulation of phospholipid scramblase activity|down regulation of phospholipid scramblase activity|inhibition of phospholipid scramblase activity|downregulation of phospholipid scramblase activity						rph	2012-03-08T10:57:23Z						biological_process											owl:Class	
GO:0050903	biolink:NamedThing	leukocyte activation-dependent arrest	The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.	got7fsn_ti														biological_process											owl:Class	
GO:0097558	biolink:NamedThing	left ventral flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc.	got7fsn_ti	left ventral cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:26:51Z						cellular_component											owl:Class	
GO:2000789	biolink:NamedThing	positive regulation of venous endothelial cell fate commitment	Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment.	got7fsn_ti							bf	2011-06-24T01:26:19Z						biological_process											owl:Class	
GO:0039677	biolink:NamedThing	exit of virus from host cell nucleus via nuclear envelope disassembly	The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus.	got7fsn_ti	exit of virus from host cell nucleus via nuclear envelope breakdown						bf	2013-09-25T14:10:03Z				VZ:2176		biological_process											owl:Class	
GO:1902388	biolink:NamedThing	ceramide 1-phosphate transfer activity	Removes a ceramide 1-phosphate from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	intermembrane ceramide 1-phosphate transfer activity|ceramide 1-phosphate carrier activity|ceramide 1-phosphate transporter activity						uh	2013-09-05T05:57:55Z				Reactome:R-HSA-5339535		molecular_function											owl:Class	
GO:1902389	biolink:NamedThing	ceramide 1-phosphate transport	The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							uh	2013-09-05T06:02:35Z						biological_process											owl:Class	
GO:1905776	biolink:NamedThing	positive regulation of DNA helicase activity	Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity.	got7fsn_ti	up-regulation of DNA helicase activity|upregulation of ATP-dependent DNA helicase activity|positive regulation of ATP-dependent DNA helicase activity|upregulation of DNA helicase activity|up regulation of DNA helicase activity|up regulation of ATP-dependent DNA helicase activity|activation of DNA helicase activity|activation of ATP-dependent DNA helicase activity|up-regulation of ATP-dependent DNA helicase activity						rb	2013-10-15T21:20:10Z			GO:1902451			biological_process											owl:Class	
GO:0003429	biolink:NamedThing	growth plate cartilage chondrocyte morphogenesis	The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.	got7fsn_ti							dph	2009-12-22T12:22:24Z						biological_process											owl:Class	
GO:0031039	biolink:NamedThing	macronucleus	A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell.	got7fsn_ti												Wikipedia:Macronucleus		cellular_component											owl:Class	
GO:0090641	biolink:NamedThing	microsporidian-type endospore	The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins.	got7fsn_ti					Microsporidian biology uses the term endospore differently than GO:0043593 endospore coat which is for a spore formed inside of another cell. Microsporidian endospore refers to the inner layer of the spore wall itself.		tb	2015-05-04T14:17:06Z						cellular_component											owl:Class	
GO:0061050	biolink:NamedThing	regulation of cell growth involved in cardiac muscle cell development	Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.	got7fsn_ti							dph	2010-02-25T01:05:16Z						biological_process											owl:Class	
GO:0043318	biolink:NamedThing	negative regulation of cytotoxic T cell degranulation	Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation.	got7fsn_ti	negative regulation of cytotoxic T-cell granule exocytosis|negative regulation of cytotoxic T lymphocyte granule exocytosis|negative regulation of cytotoxic T lymphocyte degranulation|down regulation of cytotoxic T cell degranulation|down-regulation of cytotoxic T cell degranulation|negative regulation of cytotoxic T-cell degranulation|downregulation of cytotoxic T cell degranulation|negative regulation of cytotoxic T-lymphocyte degranulation|negative regulation of cytotoxic T cell granule exocytosis|negative regulation of cytotoxic T-lymphocyte granule exocytosis|inhibition of cytotoxic T cell degranulation													biological_process											owl:Class	
GO:0090387	biolink:NamedThing	phagolysosome assembly involved in apoptotic cell clearance	The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance.	got7fsn_ti							tb	2010-10-27T10:57:39Z						biological_process											owl:Class	
GO:0090386	biolink:NamedThing	phagosome maturation involved in apoptotic cell clearance	A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.	got7fsn_ti							tb	2010-10-27T10:57:39Z						biological_process											owl:Class	
GO:0120111	biolink:NamedThing	neuron projection cytoplasm	All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.	got7fsn_ti							krc	2017-11-01T18:58:12Z						cellular_component											owl:Class	
GO:0070308	biolink:NamedThing	lens fiber cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.	got7fsn_ti	lens fibre cell fate commitment													biological_process											owl:Class	
GO:0009780	biolink:NamedThing	photosynthetic NADP+ reduction	An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions.	got7fsn_ti														biological_process											owl:Class	
GO:0043375	biolink:NamedThing	CD8-positive, alpha-beta T cell lineage commitment	The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell.	got7fsn_ti	CD8-positive, alpha-beta T-lymphocyte lineage commitment|CD8-positive, alpha-beta T cell fate commitment|CD8-positive, alpha-beta T-cell lineage commitment|CD8-positive, alpha-beta T lymphocyte lineage commitment													biological_process											owl:Class	
GO:0021714	biolink:NamedThing	inferior olivary nucleus morphogenesis	The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	got7fsn_ti	inferior olive morphogenesis													biological_process											owl:Class	
GO:0099626	biolink:NamedThing	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels.	got7fsn_ti	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels													molecular_function											owl:Class	
GO:0033364	biolink:NamedThing	mast cell secretory granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.	got7fsn_ti	mast cell secretory granule organisation|mast cell secretory granule organization and biogenesis|mast cell secretory granule maturation													biological_process											owl:Class	
GO:2000371	biolink:NamedThing	regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.	got7fsn_ti	regulation of topoisomerase II|regulation of deoxyribonucleic topoisomerase activity|regulation of DNA topoisomerase IV activity|regulation of DNA topoisomerase type II activity|regulation of DNA topoisomerase (ATP-hydrolysing)|regulation of type II DNA topoisomerase activity|regulation of deoxyribonucleate topoisomerase|regulation of topoisomerase|regulation of DNA topoisomerase II						mah	2011-02-09T02:35:27Z						biological_process											owl:Class	
GO:0015194	biolink:NamedThing	L-serine transmembrane transporter activity	Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.	got7fsn_ti	threonine/serine:sodium symporter activity|L-serine permease activity|L-serine transporter activity|serine transporter activity										GO:1905361|GO:0015511	Reactome:R-HSA-8932980		molecular_function											owl:Class	
GO:0015825	biolink:NamedThing	L-serine transport	The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-serine import						tb	2012-10-01T11:10:51Z			GO:0090479			biological_process											owl:Class	
GO:0003142	biolink:NamedThing	cardiogenic plate morphogenesis	The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.	got7fsn_ti	cardiac crescent morphogenesis						tb	2009-09-22T04:12:18Z						biological_process											owl:Class	
GO:0099521	biolink:NamedThing	ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential	Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.	got7fsn_ti	ATPase-coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential|ATPase coupled ion transmembrane transporter activity involved in regulation of pre-synaptic membrane potential													molecular_function											owl:Class	
GO:0000506	biolink:NamedThing	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast.	got7fsn_ti	GPI-GnT complex|GPI-GlcNAc transferase complex|GPI-N-acetylglucosaminyltransferase complex				Note that this term should not be confused with 'GPI-anchor transamidase complex ; GO:0042765', which represents a distinct complex with a different catalytic activity.									cellular_component											owl:Class	
GO:0035322	biolink:NamedThing	mesenchymal cell migration involved in limb bud formation	The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.	got7fsn_ti							bf	2010-02-24T02:05:14Z						biological_process											owl:Class	
GO:0090496	biolink:NamedThing	mesenchyme migration involved in limb bud formation	The migration of mesenchymal tissue that contributes to the formation of a limb bud.	got7fsn_ti							tb	2012-10-17T12:04:20Z						biological_process											owl:Class	
GO:1901218	biolink:NamedThing	negative regulation of holin activity	Any process that stops, prevents or reduces the frequency, rate or extent of holin activity.	got7fsn_ti	antiholin activity|down-regulation of holin activity|downregulation of holin activity|down regulation of holin activity|phage antiholin|inhibition of holin activity						bf	2012-08-06T10:48:00Z						biological_process											owl:Class	
GO:0098684	biolink:NamedThing	photoreceptor ribbon synapse	A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell.  These contain a plate-like synaptic ribbon.	got7fsn_ti							dos	2017-02-05T16:26:27Z						cellular_component											owl:Class	
CL:0000748	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901250	biolink:NamedThing	negative regulation of lung goblet cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation.	got7fsn_ti	downregulation of lung goblet cell differentiation|down-regulation of lung goblet cell differentiation|down-regulation of pulmonary goblet cell differentiation|downregulation of pulmonary goblet cell differentiation|inhibition of pulmonary goblet cell differentiation|down regulation of pulmonary goblet cell differentiation|inhibition of lung goblet cell differentiation|negative regulation of pulmonary goblet cell differentiation|down regulation of lung goblet cell differentiation						vk	2012-08-08T08:59:36Z						biological_process											owl:Class	
GO:0048390	biolink:NamedThing	intermediate mesoderm morphogenesis	The process in which the anatomical structures of the intermediate mesoderm are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0043322	biolink:NamedThing	negative regulation of natural killer cell degranulation	Any process that stops, prevents, or reduces the rate of natural killer cell degranulation.	got7fsn_ti	downregulation of natural killer cell degranulation|down regulation of natural killer cell degranulation|negative regulation of NK cell degranulation|inhibition of natural killer cell degranulation|down-regulation of natural killer cell degranulation|negative regulation of natural killer cell granule exocytosis|negative regulation of NK cell granule exocytosis													biological_process											owl:Class	
GO:0062094	biolink:NamedThing	stomach development	The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.	got7fsn_ti							dph	2018-11-20T18:15:45Z						biological_process											owl:Class	
GO:0031459	biolink:NamedThing	ABC-type glycine betaine transporter activity	Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).	got7fsn_ti	glycine betaine ABC transporter|ATPase-coupled glycine betaine transporter activity|ATP-dependent glycine betaine transporter activity|N-trimethylglycine-transporting ATPase activity|glycine betaine-transporting ATPase activity											RHEA:32783		molecular_function											owl:Class	
GO:0060166	biolink:NamedThing	olfactory pit development	The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx.	got7fsn_ti														biological_process											owl:Class	
GO:1903352	biolink:NamedThing	L-ornithine transmembrane transport	The directed movement of L-ornithine across a membrane.	got7fsn_ti							pr	2014-08-20T13:01:38Z						biological_process											owl:Class	
GO:0009317	biolink:NamedThing	acetyl-CoA carboxylase complex	A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.	got7fsn_ti	ACCase complex													cellular_component											owl:Class	
GO:0060419	biolink:NamedThing	heart growth	The increase in size or mass of the heart.	got7fsn_ti														biological_process											owl:Class	
GO:0030993	biolink:NamedThing	axonemal heterotrimeric kinesin-II complex	A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme.	got7fsn_ti														cellular_component											owl:Class	
GO:0010797	biolink:NamedThing	regulation of multivesicular body size involved in endosome transport	Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles.	got7fsn_ti														biological_process											owl:Class	
GO:0017154	biolink:NamedThing	semaphorin receptor activity	Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0035066	biolink:NamedThing	positive regulation of histone acetylation	Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.	got7fsn_ti	up-regulation of histone acetylation|up regulation of histone acetylation|stimulation of histone acetylation|upregulation of histone acetylation|activation of histone acetylation													biological_process											owl:Class	
GO:0009672	biolink:NamedThing	auxin:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in).	got7fsn_ti	auxin:hydrogen symporter activity													molecular_function											owl:Class	
GO:0021916	biolink:NamedThing	inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors	Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.	got7fsn_ti	inductive cell-cell signalling between paraxial mesoderm and motor neuron precursors													biological_process											owl:Class	
GO:0021917	biolink:NamedThing	somatic motor neuron fate commitment	The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0033336	biolink:NamedThing	caudal fin development	The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0070183	biolink:NamedThing	mitochondrial tryptophanyl-tRNA aminoacylation	The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
CHEBI:36915	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902233	biolink:NamedThing	negative regulation of positive thymic T cell selection	Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection.	got7fsn_ti	negative regulation of positive thymic T lymphocyte selection|down-regulation of positive thymic T lymphocyte selection|inhibition of positive thymic T cell selection|down regulation of positive thymic T-cell selection|downregulation of positive thymic T-lymphocyte selection|downregulation of positive thymic T lymphocyte selection|down regulation of positive thymic T cell selection|inhibition of positive thymic T lymphocyte selection|down-regulation of positive thymic T-cell selection|negative regulation of positive thymic T-cell selection|inhibition of positive thymic T-lymphocyte selection|down-regulation of positive thymic T cell selection|downregulation of positive thymic T-cell selection|down-regulation of positive thymic T-lymphocyte selection|inhibition of positive thymic T-cell selection|negative regulation of positive thymic T-lymphocyte selection|down regulation of positive thymic T lymphocyte selection|downregulation of positive thymic T cell selection|down regulation of positive thymic T-lymphocyte selection						lb	2013-06-14T11:19:15Z						biological_process											owl:Class	
GO:0031062	biolink:NamedThing	positive regulation of histone methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones.	got7fsn_ti	stimulation of histone methylation|activation of histone methylation|up-regulation of histone methylation|up regulation of histone methylation|upregulation of histone methylation													biological_process											owl:Class	
GO:1905081	biolink:NamedThing	positive regulation of cerebellar neuron development	Any process that activates or increases the frequency, rate or extent of cerebellar neuron development.	got7fsn_ti	activation of cerebellar neuron development|upregulation of cerebellar neuron development|up regulation of cerebellar neuron development|up-regulation of cerebellar neuron development						hjd	2016-03-24T19:45:35Z						biological_process											owl:Class	
GO:0035203	biolink:NamedThing	regulation of lamellocyte differentiation	Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.	got7fsn_ti														biological_process											owl:Class	
GO:0061056	biolink:NamedThing	sclerotome development	The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.	got7fsn_ti							dph	2010-03-02T12:12:40Z						biological_process											owl:Class	
GO:1904840	biolink:NamedThing	positive regulation of male germ-line stem cell asymmetric division	Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division.	got7fsn_ti	up regulation of male germ-line stem cell renewal|activation of male germ-line stem cell renewal|up-regulation of male germ-line stem cell asymmetric division|upregulation of male germ-line stem cell asymmetric division|up-regulation of male germ-line stem cell renewal|activation of male germ-line stem cell asymmetric division|up regulation of male germ-line stem cell asymmetric division|upregulation of male germ-line stem cell renewal|positive regulation of male germ-line stem cell renewal						sl	2015-12-05T00:28:46Z						biological_process											owl:Class	
GO:0009376	biolink:NamedThing	HslUV protease complex	A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer.	got7fsn_ti	ClpYQ protease complex													cellular_component											owl:Class	
GO:0004176	biolink:NamedThing	ATP-dependent peptidase activity	Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent proteolysis	https://github.com/geneontology/go-ontology/issues/21612									GO:0004280	Reactome:R-HSA-9698929		molecular_function											owl:Class	
GO:0043211	biolink:NamedThing	ABC-type carbohydrate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane.	got7fsn_ti	ATPase-coupled carbohydrate transmembrane transporter activity|carbohydrate ABC transporter|ATP-dependent carbohydrate transmembrane transporter activity|carbohydrate-transporting ATPase activity	https://github.com/geneontology/go-ontology/issues/17289												molecular_function											owl:Class	
GO:0034219	biolink:NamedThing	carbohydrate transmembrane transport	The process in which a carbohydrate is transported across a membrane.	got7fsn_ti	transmembrane carbohydrate transport|carbohydrate membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:0061737	biolink:NamedThing	leukotriene signaling pathway	A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-leukotriene interaction and ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti							dph	2015-09-15T12:58:21Z						biological_process											owl:Class	
GO:1905468	biolink:NamedThing	regulation of clathrin-coated pit assembly	Any process that modulates the frequency, rate or extent of clathrin-coated pit assembly.	got7fsn_ti	regulation of clathrin-coated pit formation|regulation of coated pit formation|regulation of coated pit assembly						bf	2016-09-20T10:04:37Z						biological_process											owl:Class	
GO:0036479	biolink:NamedThing	peroxidase inhibitor activity	Binds to and stops, prevents or reduces the activity of peroxidase.	got7fsn_ti					GO:0036479 is reserved for cases when the inhibitor directly interacts with the peroxidase. When inhibition of peroxidase activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'negative regulation of peroxidase activity ; GO:2000469'.		bf	2014-07-24T10:14:45Z						molecular_function											owl:Class	
GO:0075009	biolink:NamedThing	germ tube formation	Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	germ tube formation on or near host													biological_process											owl:Class	
GO:0086086	biolink:NamedThing	voltage-gated potassium channel activity involved in AV node cell action potential repolarization	Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated potassium channel activity involved in AV node cardiac muscle cell action potential repolarization|voltage-gated potassium channel activity involved in atrioventricular node cardiac muscle cell action potential						dph	2011-11-22T01:26:32Z						molecular_function											owl:Class	
GO:0086049	biolink:NamedThing	membrane repolarization during AV node cell action potential	The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	got7fsn_ti	membrane repolarization involved in regulation of AV node cardiac muscle cell action potential|membrane repolarization involved in regulation of atrioventricular node cardiac muscle cell action potential						dph	2011-11-16T11:43:38Z						biological_process											owl:Class	
GO:2001233	biolink:NamedThing	regulation of apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.	got7fsn_ti	regulation of apoptotic signalling pathway						pr	2011-11-24T01:20:49Z						biological_process											owl:Class	
GO:0005948	biolink:NamedThing	acetolactate synthase complex	A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate.	got7fsn_ti	acetohydroxyacid synthase complex				See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.									cellular_component											owl:Class	
GO:0060091	biolink:NamedThing	kinocilium	A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia.	got7fsn_ti												Wikipedia:Kinocilium		cellular_component											owl:Class	
GO:0019183	biolink:NamedThing	histamine-gated chloride channel complex	A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts.	got7fsn_ti														cellular_component											owl:Class	
GO:1904381	biolink:NamedThing	Golgi apparatus mannose trimming	Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus.	got7fsn_ti	glycoprotein mannose trimming in Golgi apparatus|mannose trimming in Golgi|mannose trimming in Golgi apparatus|glycoprotein mannose trimming in Golgi complex|protein alpha-1,2-demannosylation in Golgi complex|protein alpha-1,2-demannosylation in Golgi apparatus|glycoprotein mannose trimming in Golgi ribbon|protein alpha-1,2-demannosylation in Golgi ribbon|mannose trimming in cis-Golgi						bf	2015-06-23T09:42:06Z						biological_process											owl:Class	
GO:0071004	biolink:NamedThing	U2-type prespliceosome	A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.	got7fsn_ti	major prespliceosome|GT-AG prespliceosome|mammalian U2-type spliceosomal complex A|yeast U2-type spliceosomal complex B						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0072008	biolink:NamedThing	glomerular mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state.	got7fsn_ti							mah	2010-01-25T01:59:33Z						biological_process											owl:Class	
GO:0030989	biolink:NamedThing	dynein-driven meiotic oscillatory nuclear movement	Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein.	got7fsn_ti	horsetail nuclear movement|HNM|horsetail movement				Dynein-driven meiotic oscillatory nuclear movement precedes meiotic recombination.									biological_process											owl:Class	
GO:0004666	biolink:NamedThing	prostaglandin-endoperoxide synthase activity	Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.	got7fsn_ti	prostaglandin synthase activity|PG synthetase activity|prostaglandin synthetase activity|prostaglandin endoperoxide synthetase activity|prostaglandin G/H synthase activity|(PG)H synthase activity|(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity|fatty acid cyclooxygenase activity											EC:1.14.99.1|MetaCyc:PROSTAGLANDIN-ENDOPEROXIDE-SYNTHASE-RXN|Reactome:R-HSA-140355|Reactome:R-HSA-2309787|RHEA:23728		molecular_function											owl:Class	
GO:0061825	biolink:NamedThing	podosome core	The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.	got7fsn_ti							dph	2017-01-14T14:42:45Z						cellular_component											owl:Class	
GO:0097239	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to methylglyoxal	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a methylglyoxal stimulus.	got7fsn_ti							pr	2012-02-02T12:28:46Z						biological_process											owl:Class	
GO:0061444	biolink:NamedThing	endocardial cushion cell development	The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state.	got7fsn_ti							dph	2012-03-13T09:07:46Z						biological_process											owl:Class	
GO:0021769	biolink:NamedThing	orbitofrontal cortex development	The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe.	got7fsn_ti														biological_process											owl:Class	
GO:0030420	biolink:NamedThing	establishment of competence for transformation	The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation.	got7fsn_ti														biological_process											owl:Class	
GO:0009294	biolink:NamedThing	DNA mediated transformation	The introduction and uptake of foreign genetic material (DNA or RNA) into a cell, and often the expression of that genetic material.	got7fsn_ti	DNA-mediated transformation													biological_process											owl:Class	
GO:0006284	biolink:NamedThing	base-excision repair	In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.	got7fsn_ti	BER											Wikipedia:Base_excision_repair		biological_process											owl:Class	
GO:0007571	biolink:NamedThing	age-dependent general metabolic decline	A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis.	got7fsn_ti	age-dependent decreased translational activity|age-dependent yeast cell size increase|age-dependent increased protein content|nucleolar size increase													biological_process											owl:Class	
GO:1905393	biolink:NamedThing	plant organ formation	The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti							tb	2016-08-24T00:21:27Z						biological_process											owl:Class	
GO:1902301	biolink:NamedThing	galactarate transmembrane transporter activity	Enables the transfer of galactaric acid anion (galactarate) from one side of a membrane to the other.	got7fsn_ti	D-galactarate transmembrane transporter activity|galactaric acid anion transmembrane transporter activity						pr	2013-07-16T07:26:36Z			GO:0042877			molecular_function											owl:Class	
GO:1902300	biolink:NamedThing	galactarate transmembrane transport	The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	galactaric acid anion transport|D-galactarate transport|galactarate transport						pr	2013-07-16T07:11:45Z			GO:0042871			biological_process											owl:Class	
GO:0044494	biolink:NamedThing	envenomation resulting in positive regulation of voltage-gated sodium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism.	got7fsn_ti							jl	2012-02-01T01:29:25Z						biological_process											owl:Class	
GO:0031163	biolink:NamedThing	metallo-sulfur cluster assembly	The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster.	got7fsn_ti	metallo-sulphur cluster assembly|metal-sulfur cluster assembly|metallo-sulfur cluster biosynthesis													biological_process											owl:Class	
GO:0106023	biolink:NamedThing	regulation of pupariation	Any process that modulates the onset of pupariation.	got7fsn_ti							hjd	2017-05-24T19:31:39Z						biological_process											owl:Class	
GO:0000223	biolink:NamedThing	plasma membrane proton-transporting V-type ATPase, V1 domain	The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane.	got7fsn_ti	plasma membrane hydrogen ion-transporting ATPase V1 domain													cellular_component											owl:Class	
GO:0033181	biolink:NamedThing	plasma membrane proton-transporting V-type ATPase complex	A proton-transporting two-sector ATPase complex found in the plasma membrane.	got7fsn_ti	plasma membrane hydrogen ion-transporting ATPase													cellular_component											owl:Class	
GO:0071002	biolink:NamedThing	U4atac/U6atac snRNP	A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes.	got7fsn_ti							mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0071952	biolink:NamedThing	conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA	The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA.	got7fsn_ti					Note that this process has been observed in some archaeal and bacterial species.		mah	2010-10-08T12:02:00Z						biological_process											owl:Class	
GO:0007361	biolink:NamedThing	establishment of posterior gap gene boundaries	Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps.	got7fsn_ti														biological_process											owl:Class	
GO:0007359	biolink:NamedThing	posterior abdomen determination	The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.	got7fsn_ti					Note that this process is exemplified in insects by the actions of the knirps gene product.									biological_process											owl:Class	
GO:1901890	biolink:NamedThing	positive regulation of cell junction assembly	Any process that activates or increases the frequency, rate or extent of cell junction assembly.	got7fsn_ti	up-regulation of cell junction assembly|up regulation of cell junction assembly|activation of cell junction assembly|upregulation of cell junction assembly						tb	2013-02-06T19:40:46Z						biological_process											owl:Class	
GO:0009427	biolink:NamedThing	bacterial-type flagellum basal body, distal rod, L ring	One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the outer membrane.	got7fsn_ti	flagellin-based flagellum basal body, distal rod, L ring|flagellar basal body, distal rod, L ring													cellular_component											owl:Class	
GO:0001792	biolink:NamedThing	polymeric immunoglobulin receptor activity	Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0001790	biolink:NamedThing	polymeric immunoglobulin binding	Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.	got7fsn_ti														molecular_function											owl:Class	
GO:0048702	biolink:NamedThing	embryonic neurocranium morphogenesis	The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.	got7fsn_ti	embryonic chondrocranium morphogenesis|embryonic braincase morphogenesis													biological_process											owl:Class	
GO:0021985	biolink:NamedThing	neurohypophysis development	The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.	got7fsn_ti	posterior pituitary gland development|neurophysis development|posterior pituitary development													biological_process											owl:Class	
GO:0072495	biolink:NamedThing	host cell Cajal body	A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	host cell coiled body|coiled body of host						mah	2010-12-15T11:51:12Z						cellular_component											owl:Class	
GO:0032217	biolink:NamedThing	riboflavin transmembrane transporter activity	Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.	got7fsn_ti	riboflavin transporter activity											RHEA:35015|Reactome:R-HSA-3165230		molecular_function											owl:Class	
GO:0036470	biolink:NamedThing	tyrosine 3-monooxygenase activator activity	Interacts with and increases tyrosine 3-monooxygenase (tyrosine hydroxylase) activity.	got7fsn_ti	tyrosine hydroxylase activator activity|TH activator activity						bf	2014-07-21T11:06:49Z						molecular_function											owl:Class	
GO:0004511	biolink:NamedThing	tyrosine 3-monooxygenase activity	Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.	got7fsn_ti	L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|tyrosine hydroxylase activity|tyrosine 3-hydroxylase activity|L-tyrosine hydroxylase activity											Reactome:R-HSA-209823|EC:1.14.16.2|RHEA:18201|MetaCyc:TYROSINE-3-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:1902437	biolink:NamedThing	positive regulation of male mating behavior	Any process that activates or increases the frequency, rate or extent of male mating behavior.	got7fsn_ti	activation of male mating behavior|upregulation of male mating behavior|up regulation of male mating behavior|up-regulation of male mating behavior						mm2	2013-10-09T15:50:14Z						biological_process											owl:Class	
GO:0140584	biolink:NamedThing	chromatin extrusion motor activity	A DNA translocase activity that folds chromosomal DNA and catalytically extends the newly formed loop, driven by ATP hydrolysis.	got7fsn_ti	chromatin extrusion activity	https://github.com/geneontology/go-ontology/issues/21647|https://github.com/geneontology/go-ontology/issues/20204					pg	2021-02-01T13:42:08Z						molecular_function											owl:Class	
GO:0140588	biolink:NamedThing	chromatin looping	A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome.	got7fsn_ti	chromatin folding|chromatin loop assembly	https://github.com/geneontology/go-ontology/issues/20204					pg	2021-02-04T14:55:20Z						biological_process											owl:Class	
GO:0097560	biolink:NamedThing	left caudal flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.	got7fsn_ti	left caudal cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:29:44Z						cellular_component											owl:Class	
GO:0033101	biolink:NamedThing	cellular bud membrane	The portion of the plasma membrane surrounding a cellular bud.	got7fsn_ti	cellular bud plasma membrane													cellular_component											owl:Class	
GO:0042647	biolink:NamedThing	proplastid nucleoid	The region of a proplastid to which the DNA is confined.	got7fsn_ti														cellular_component											owl:Class	
GO:0009571	biolink:NamedThing	proplastid stroma	The space enclosed by the double membrane of a proplastid.	got7fsn_ti														cellular_component											owl:Class	
GO:0048398	biolink:NamedThing	intermediate mesodermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	intermediate mesoderm cell fate specification													biological_process											owl:Class	
GO:0045899	biolink:NamedThing	positive regulation of RNA polymerase II transcription preinitiation complex assembly	Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.	got7fsn_ti	positive regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|positive regulation of RNA polymerase II transcriptional pre-initiation complex assembly|positive regulation of RNA polymerase II transcriptional preinitiation complex formation|upregulation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of RNA polymerase II transcriptional preinitiation complex assembly|activation of RNA polymerase II transcriptional preinitiation complex assembly|stimulation of RNA polymerase II transcriptional preinitiation complex assembly|up regulation of RNA polymerase II transcriptional preinitiation complex assembly|up-regulation of RNA polymerase II transcriptional preinitiation complex assembly													biological_process											owl:Class	
GO:0150064	biolink:NamedThing	vertebrate eye-specific patterning	Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus.	got7fsn_ti	vertebrate eye-specific segregation|eye-specific segregation|binocular vision development|eye-specific patterning						bc	2018-07-23T10:39:44Z						biological_process											owl:Class	
GO:0050969	biolink:NamedThing	detection of chemical stimulus involved in magnetoreception	The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states.	got7fsn_ti	sensory transduction of chemical stimulus during magnetoreception|magnetoreception, sensory transduction of chemical stimulus|magnetoreception, detection of chemical stimulus|magnetoreception, sensory detection of chemical stimulus|sensory detection of chemical stimulus during magnetoreception|magnetoception, sensory transduction of chemical stimulus													biological_process											owl:Class	
GO:0009547	biolink:NamedThing	plastid ribosome	A ribosome contained within a plastid.	got7fsn_ti														cellular_component											owl:Class	
GO:1904877	biolink:NamedThing	positive regulation of DNA ligase activity	Any process that activates or increases the frequency, rate or extent of DNA ligase activity.	got7fsn_ti	up-regulation of DNA ligase activity|upregulation of DNA ligase activity|activation of DNA ligase activity|up regulation of DNA ligase activity						rl	2015-12-18T18:35:44Z						biological_process											owl:Class	
GO:0006266	biolink:NamedThing	DNA ligation	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.	got7fsn_ti														biological_process											owl:Class	
GO:1903761	biolink:NamedThing	negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.	got7fsn_ti	inhibition of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|down regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|downregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|inhibition of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|negative regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|negative regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|inhibition of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential						rl	2014-12-19T12:02:09Z						biological_process											owl:Class	
GO:0098915	biolink:NamedThing	membrane repolarization during ventricular cardiac muscle cell action potential	The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	got7fsn_ti	electrocardiogram T wave|ventricular repolarization|regulation of ventricular cardiac muscle repolarization													biological_process											owl:Class	
GO:0015184	biolink:NamedThing	L-cystine transmembrane transporter activity	Enables the transfer of L-cystine from one side of a membrane to the other.	got7fsn_ti	L-cystine transporter activity|cystine/diaminopimelate porter activity											Reactome:R-HSA-5340130		molecular_function											owl:Class	
GO:0015811	biolink:NamedThing	L-cystine transport	The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0060128	biolink:NamedThing	corticotropin hormone secreting cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.	got7fsn_ti	adrenocorticotrophic hormone secreting cell differentiation|adrenocorticotropic hormone secreting cell differentiation|corticotrope differentiation|corticotrophin hormone secreting cell differentiation|corticotroph differentiation													biological_process											owl:Class	
GO:0045022	biolink:NamedThing	early endosome to late endosome transport	The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.	got7fsn_ti														biological_process											owl:Class	
GO:0038122	biolink:NamedThing	C-C motif chemokine 5 receptor activity	Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	RANTES receptor activity|small inducible cytokine A5 receptor activity|CCL5 receptor activity						bf	2012-03-22T01:36:00Z						molecular_function											owl:Class	
GO:0035689	biolink:NamedThing	chemokine (C-C motif) ligand 5 signaling pathway	A series of molecular signals initiated by the binding of the chemokine CCL5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CCL5-mediated signaling pathway|RANTES-mediated signaling pathway|chemokine (C-C motif) ligand 5 signalling pathway						bf	2011-02-24T12:56:13Z						biological_process											owl:Class	
GO:2000077	biolink:NamedThing	negative regulation of type B pancreatic cell development	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.	got7fsn_ti	negative regulation of pancreatic beta cell development|negative regulation of pancreatic B cell development						tb	2010-08-27T11:21:17Z						biological_process											owl:Class	
GO:0090718	biolink:NamedThing	adaptive immune effector response	An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response.	got7fsn_ti							tb	2016-11-11T12:37:26Z						biological_process											owl:Class	
GO:0051415	biolink:NamedThing	microtubule nucleation by interphase microtubule organizing center	The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.	got7fsn_ti	IMTOC-mediated microtubule nucleation during interphase|interphase microtubule organizing center-mediated microtubule nucleation during interphase|microtubule nucleation during interphase by interphase microtubule organizing center|microtubule nucleation during interphase by IMTOC|interphase microtubule nucleation by interphase microtubule organizing center|interphase microtubule nucleation by interphase microtubule organising centre													biological_process											owl:Class	
GO:0007533	biolink:NamedThing	mating type switching	The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.	got7fsn_ti	mating type switching and recombination													biological_process											owl:Class	
GO:0045697	biolink:NamedThing	regulation of synergid differentiation	Any process that modulates the frequency, rate or extent of synergid cell differentiation.	got7fsn_ti	regulation of synergid cell differentiation													biological_process											owl:Class	
CL:0000160	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019973	biolink:NamedThing	interleukin-13 binding	Binding to interleukin-13.	got7fsn_ti	IL-13 binding													molecular_function											owl:Class	
GO:0000815	biolink:NamedThing	ESCRT III complex	An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes.	got7fsn_ti	endosomal sorting complex required for transport													cellular_component											owl:Class	
GO:0060701	biolink:NamedThing	negative regulation of ribonuclease activity	Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.	got7fsn_ti							dph	2009-06-08T02:49:46Z						biological_process											owl:Class	
GO:0060336	biolink:NamedThing	negative regulation of interferon-gamma-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.	got7fsn_ti	negative regulation of interferon-gamma-mediated signalling pathway|negative regulation of immune interferon-mediated signaling pathway|negative regulation of type II interferon-mediated signaling pathway|negative regulation of type II IFN-mediated signaling pathway|negative regulation of gamma-interferon-mediated signaling pathway													biological_process											owl:Class	
GO:0036395	biolink:NamedThing	pancreatic amylase secretion	The controlled release of amylase from a cell of the pancreas.	got7fsn_ti							bf	2013-07-01T13:42:34Z						biological_process											owl:Class	
GO:0061451	biolink:NamedThing	retrotrapezoid nucleus development	The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.	got7fsn_ti							dph	2012-07-19T12:38:30Z						biological_process											owl:Class	
GO:0031204	biolink:NamedThing	posttranslational protein targeting to membrane, translocation	The process in which a protein translocates through the ER membrane posttranslationally.	got7fsn_ti	protein translocation during posttranslational protein targeting to membrane|posttranslational protein membrane targeting, translocation													biological_process											owl:Class	
GO:0060129	biolink:NamedThing	thyroid-stimulating hormone-secreting cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.	got7fsn_ti	TSH-secreting cell differentiation|thyrotroph differentiation|thyroid stimulating hormone secreting cell differentiation|beta-basophil differentiation|thyrotrope differentiation													biological_process											owl:Class	
GO:1905221	biolink:NamedThing	positive regulation of platelet formation	Any process that activates or increases the frequency, rate or extent of platelet formation.	got7fsn_ti	up regulation of platelet extrusion|up regulation of platelet formation|up-regulation of platelet formation|positive regulation of platelet extrusion|upregulation of platelet extrusion|activation of platelet formation|up-regulation of platelet extrusion|activation of platelet extrusion|upregulation of platelet formation						sl	2016-06-06T22:16:02Z						biological_process											owl:Class	
CHEBI:48433	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061211	biolink:NamedThing	mesonephric collecting duct development	The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.	got7fsn_ti							dph	2010-08-17T03:25:51Z						biological_process											owl:Class	
GO:0120191	biolink:NamedThing	negative regulation of termination of RNA polymerase II transcription	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.	got7fsn_ti	repression of termination of RNA polymerase II transcription|down regulation of RNA 3'-end formation by RNA polymerase II|negative regulation of RNA polymerase II transcription termination factor activity|downregulation of RNA 3'-end formation by RNA polymerase II|down regulation of transcription termination from RNA polymerase II promoter|down-regulation of termination of RNA polymerase II transcription|negative regulation of RNA polymerase II transcription termination|negative regulation of transcription termination from Pol II promoter|downregulation of transcription termination from Pol II promoter|downregulation of RNA polymerase II transcription termination factor activity|down regulation of transcription termination from Pol II promoter|down regulation of RNA polymerase II transcription termination|down regulation of termination of RNA polymerase II transcription|downregulation of transcription termination from RNA polymerase II promoter|down-regulation of RNA polymerase II transcription termination|down regulation of RNA polymerase II transcription termination factor activity|down-regulation of RNA polymerase II transcription termination factor activity|downregulation of termination of RNA polymerase II transcription|repression of transcription termination from Pol II promoter|down-regulation of transcription termination from RNA polymerase II promoter|repression of RNA polymerase II transcription termination factor activity|negative regulation of transcription termination from RNA polymerase II promoter|down-regulation of transcription termination from Pol II promoter|negative regulation of RNA 3'-end formation by RNA polymerase II|repression of RNA polymerase II transcription termination|repression of RNA 3'-end formation by RNA polymerase II|down-regulation of RNA 3'-end formation by RNA polymerase II|downregulation of RNA polymerase II transcription termination|repression of transcription termination from RNA polymerase II promoter						krc	2018-07-18T15:43:40Z						biological_process											owl:Class	
GO:1990512	biolink:NamedThing	Cry-Per complex	Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms.	got7fsn_ti					An example of this is Cry1 in mouse (P97784) in PMID:24855952 (inferred from physical interaction).		bhm	2014-10-08T10:53:07Z						cellular_component											owl:Class	
GO:0008270	biolink:NamedThing	zinc ion binding	Binding to a zinc ion (Zn).	got7fsn_ti	Zn binding|zinc binding													molecular_function											owl:Class	
GO:0032515	biolink:NamedThing	negative regulation of phosphoprotein phosphatase activity	Any process that stops or reduces the activity of a phosphoprotein phosphatase.	got7fsn_ti	down regulation of phosphoprotein phosphatase activity|down regulation of protein phosphatase 2 activity|inhibition of protein phosphatase 3 activity|down regulation of protein phosphatase 3 activity|inhibition of protein phosphatase type 2A activity|down-regulation of phosphoprotein phosphatase activity|downregulation of calcineurin activity|downregulation of protein phosphatase 3 activity|regulation of protein phosphatase 3 activity|downregulation of protein phosphatase type 2B activity|down-regulation of protein phosphatase type 2A activity|negative regulation of calcineurin activity|inhibition of phosphoprotein phosphatase activity|downregulation of protein phosphatase type 2A activity|negative regulation of protein phosphatase 2 activity|downregulation of protein phosphatase 2 activity|downregulation of phosphoprotein phosphatase activity|negative regulation of protein phosphatase type 2B activity|inhibition of calcineurin activity|down-regulation of protein phosphatase type 2B activity|negative regulation of protein phosphatase type 2A activity|down regulation of protein phosphatase type 2B activity|down regulation of protein phosphatase type 2A activity|inhibition of protein phosphatase 2 activity|down regulation of calcineurin activity|inhibition of protein phosphatase type 2B activity										GO:0034048|GO:0032513			biological_process											owl:Class	
GO:1990433	biolink:NamedThing	CSL-Notch-Mastermind transcription factor complex	A DNA-binding transcription factor complex consisting of CSL and mastermind proteins in complex with the cleaved, intracellular domain of Notch. It is required for both repression and activation of Notch target genes.	got7fsn_ti	CSL-NotchIC-MASTERMIND complex						bhm	2014-07-30T14:41:43Z						cellular_component											owl:Class	
GO:0033040	biolink:NamedThing	sour taste receptor activity	Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste.	got7fsn_ti														molecular_function											owl:Class	
GO:0001581	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of sour taste	The series of events required for a sour taste stimulus to be received and converted to a molecular signal.	got7fsn_ti	sensory transduction of chemical stimulus during perception of sour taste|sensory transduction of sour taste|sensory detection of chemical stimulus during perception of sour taste|perception of sour taste, detection of chemical stimulus|sour taste detection|sensory detection of sour taste|perception of sour taste, sensory transduction of chemical stimulus													biological_process											owl:Class	
NCBITaxon:5740	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098944	biolink:NamedThing	postsynaptic recycling endosome membrane	The lipid bilayer surrounding a postsynaptic recycling endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0098837	biolink:NamedThing	postsynaptic recycling endosome	A recycling endosome of the postsynapse. In postsynaptic terminals with dendritic spines, it is typically located at the base of a dendritic spine. It is involved in recycling of neurotransmitter receptors to the postsynaptic membrane.  In some cases at least, this recycling is activated by postsynaptic signalling and so can play a role in long term potentiation.	got7fsn_ti	postsynaptic endosomal recycling compartment|postsynaptic recycling outpost													cellular_component											owl:Class	
GO:2000558	biolink:NamedThing	positive regulation of immunoglobulin production in mucosal tissue	Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue.	got7fsn_ti	positive regulation of antibody production in mucosal tissue						ebc	2011-04-03T07:52:17Z						biological_process											owl:Class	
GO:0010169	biolink:NamedThing	thioglucosidase complex	A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds.	got7fsn_ti	myrosinase complex													cellular_component											owl:Class	
GO:0007297	biolink:NamedThing	ovarian follicle cell migration	The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.	got7fsn_ti	follicle cell migration													biological_process											owl:Class	
GO:0009537	biolink:NamedThing	proplastid	The precursor of other plastids.	got7fsn_ti														cellular_component											owl:Class	
GO:0043243	biolink:NamedThing	positive regulation of protein-containing complex disassembly	Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.	got7fsn_ti	activation of protein complex disassembly|upregulation of protein complex disassembly|positive regulation of protein complex disassembly|up regulation of protein complex disassembly|stimulation of protein complex disassembly|up-regulation of protein complex disassembly													biological_process											owl:Class	
GO:0006449	biolink:NamedThing	regulation of translational termination	Any process that modulates the frequency, rate or extent of translational termination.	got7fsn_ti														biological_process											owl:Class	
GO:0198738	biolink:NamedThing	cell-cell signaling by wnt	Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell.	got7fsn_ti														biological_process											owl:Class	
GO:0039673	biolink:NamedThing	evasion by virus of host dendritic cell activity	Any process by which a virus avoids the effects mediated by the host organism's dendritic cells.	got7fsn_ti	evasion by virus of host dendritic cell response|impairing dendritic cell function by virus|modulation of host dendritic cell activity by virus						bf	2013-09-25T11:18:51Z						biological_process											owl:Class	
CL:0000451	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015210	biolink:NamedThing	uracil transmembrane transporter activity	Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other.	got7fsn_ti	uracil/uridine permease activity													molecular_function											owl:Class	
GO:1903791	biolink:NamedThing	uracil transmembrane transport	The process in which uracil is transported across a membrane.	got7fsn_ti							vw	2015-01-12T10:15:25Z						biological_process											owl:Class	
GO:0051740	biolink:NamedThing	ethylene binding	Binding to ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.	got7fsn_ti	ethene binding													molecular_function											owl:Class	
GO:0008358	biolink:NamedThing	maternal determination of anterior/posterior axis, embryo	The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.	got7fsn_ti														biological_process											owl:Class	
GO:0002024	biolink:NamedThing	diet induced thermogenesis	The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0000738	biolink:NamedThing	DNA catabolic process, exonucleolytic	The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.	got7fsn_ti	DNA degradation, exonucleolytic|exonucleolytic degradation of DNA|DNA breakdown, exonucleolytic													biological_process											owl:Class	
GO:0010847	biolink:NamedThing	regulation of chromatin assembly	Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.	got7fsn_ti														biological_process											owl:Class	
GO:1990682	biolink:NamedThing	CSF1-CSF1R complex	A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand.	got7fsn_ti	M-CSF:C-FMS complex|M-CSF:CSF1R complex|M-CSF:FMS complex|CSF1:C-FMS complex|macrophage colony-stimulating factor:receptor complex						bf	2015-03-10T12:23:03Z						cellular_component											owl:Class	
GO:0019284	biolink:NamedThing	L-methionine salvage from S-adenosylmethionine	The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine.	got7fsn_ti	L-methionine synthesis from S-adenosylmethionine|L-methionine formation from S-adenosylmethionine													biological_process											owl:Class	
UBERON:0002108	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003414	biolink:NamedThing	chondrocyte morphogenesis involved in endochondral bone morphogenesis	The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.	got7fsn_ti							dph	2009-12-22T08:42:55Z						biological_process											owl:Class	
GO:0019013	biolink:NamedThing	viral nucleocapsid	The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.	got7fsn_ti	core|nucleocapsid										GO:0019014			cellular_component											owl:Class	
GO:0021957	biolink:NamedThing	corticospinal tract morphogenesis	Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.	got7fsn_ti	CST axonogenesis|corticospinal tract axonogenesis													biological_process											owl:Class	
GO:0014003	biolink:NamedThing	oligodendrocyte development	The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.	got7fsn_ti	oligodendrocyte cell development													biological_process											owl:Class	
GO:2000553	biolink:NamedThing	positive regulation of T-helper 2 cell cytokine production	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.	got7fsn_ti	positive regulation of Th2 cell cytokine production						ebc	2011-04-03T07:32:58Z						biological_process											owl:Class	
GO:0034494	biolink:NamedThing	microneme lumen	The volume enclosed by the microneme membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0030709	biolink:NamedThing	border follicle cell delamination	The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration.	got7fsn_ti	border cell delamination													biological_process											owl:Class	
GO:0001530	biolink:NamedThing	lipopolysaccharide binding	Binding to a lipopolysaccharide.	got7fsn_ti	endotoxin binding|LPS binding													molecular_function											owl:Class	
GO:0005702	biolink:NamedThing	polytene chromosome weak point	A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization.	got7fsn_ti	constriction													cellular_component											owl:Class	
GO:0015567	biolink:NamedThing	alkane transmembrane transporter activity	Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.	got7fsn_ti														molecular_function											owl:Class	
GO:0015895	biolink:NamedThing	alkane transport	The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.	got7fsn_ti														biological_process											owl:Class	
GO:0090166	biolink:NamedThing	Golgi disassembly	A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.	got7fsn_ti							tb	2009-12-08T09:15:11Z						biological_process											owl:Class	
GO:0048313	biolink:NamedThing	Golgi inheritance	The partitioning of Golgi apparatus between daughter cells at cell division.	got7fsn_ti	Golgi partitioning|Golgi division													biological_process											owl:Class	
GO:0061857	biolink:NamedThing	endoplasmic reticulum stress-induced pre-emptive quality control	The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.	got7fsn_ti	ER stress-indiced pre-emptive quality control|ER pQC						dph	2017-03-28T13:05:03Z						biological_process											owl:Class	
GO:1990476	biolink:NamedThing	synaptic vesicle, resting pool	A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation  causes a saturating degree of vesicular turnover.  50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool.	got7fsn_ti	resting pool of synaptic vesicles|reserve pool of synaptic vesicles						pr	2014-09-02T09:12:37Z						cellular_component											owl:Class	
GO:0031941	biolink:NamedThing	filamentous actin	A two-stranded helical polymer of the protein actin.	got7fsn_ti	F-actin				Note that this term refers only to the actin portion of a microfilament, and does not encompass associated proteins. See also the cellular component term 'actin filament ; GO:0005884'.							Wikipedia:Actin		cellular_component											owl:Class	
GO:1990909	biolink:NamedThing	Wnt signalosome	A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein.	got7fsn_ti	LRP6 signalosome|LRP5/6 signalosome|Wnt-LRP5/6 signalosome|Wnt signalosome complex				Within the Wnt signalosome, beta-catenin phosphorylation is inhibited through internalization of the signalosome complex, resulting in the sequestration of GSK3-beta into multi-vesicular bodies. No longer phosphorylated and targeted for degradation, beta-catenin is free to enter the nucleus and modulate downstream transcription.		bf	2015-12-07T14:04:23Z						cellular_component											owl:Class	
GO:0030719	biolink:NamedThing	P granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.	got7fsn_ti	polar granule organisation|P granule organization and biogenesis|polar granule organization and biogenesis										GO:0048114			biological_process											owl:Class	
GO:0003327	biolink:NamedThing	type B pancreatic cell fate commitment	The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.	got7fsn_ti	pancreatic B cell fate commitment						dph	2009-11-02T08:31:24Z						biological_process											owl:Class	
GO:0070648	biolink:NamedThing	formin-nucleated actin cable	An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.	got7fsn_ti							mah	2009-05-12T02:09:57Z						cellular_component											owl:Class	
GO:0044012	biolink:NamedThing	histone acetyltransferase activity (H2A-K9 specific)	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9).	got7fsn_ti	histone lysine N-acetyltransferase activity (H2A-K9 specific)													molecular_function											owl:Class	
GO:0043978	biolink:NamedThing	histone H2A-K9 acetylation	The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 9 of the histone.	got7fsn_ti	histone H2A acetylation at K9													biological_process											owl:Class	
GO:1990647	biolink:NamedThing	C/EBP complex	A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities.	got7fsn_ti	C/EBPalpha homodimer complex|C/EBP transcription factor complex|C/EBPbeta homodimer complex|C/EBPalpha complex|C/EBPbeta complex|C/EBP homodimer complex				An example of this is Cebpa in rat (P05554) in PMID:8657121 (inferred from direct assay).		bhm	2015-02-19T11:00:09Z						cellular_component											owl:Class	
GO:0034647	biolink:NamedThing	histone H3-tri/di/monomethyl-lysine-4 demethylase activity	Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone demethylase activity (H3-trimethyl-K4 specific)|histone demethylase activity (H3-K4-me3 specific)|histone H3-K4me2 demethylase activity|histone H3K4me2 demethylase activity|H3K4me3 demethylase activity|histone H3-K4me3 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089										EC:1.14.11.67|RHEA:60208		molecular_function											owl:Class	
GO:0034721	biolink:NamedThing	histone H3-K4 demethylation, trimethyl-H3-K4-specific	The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.	got7fsn_ti	H3K4 demethylation (me3)|histone H3-K4 tridemethylation													biological_process											owl:Class	
GO:0007400	biolink:NamedThing	neuroblast fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.	got7fsn_ti	neuroblast cell fate determination|neuroblast identity determination										GO:0043348|GO:0007408|GO:0043347			biological_process											owl:Class	
GO:0030256	biolink:NamedThing	type I protein secretion system complex	A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space.	got7fsn_ti	ABC translocator complex													cellular_component											owl:Class	
GO:0110131	biolink:NamedThing	Aim21-Tda2 complex	A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables.	got7fsn_ti	Aim21/Tda2 complex						kmv	2018-10-09T21:08:36Z						cellular_component											owl:Class	
GO:0030837	biolink:NamedThing	negative regulation of actin filament polymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.	got7fsn_ti	down regulation of actin filament polymerization|downregulation of actin filament polymerization|negative regulation of actin polymerization and/or depolymerization|down-regulation of actin filament polymerization|inhibition of actin filament polymerization|negative regulation of actin polymerization				Note that this term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin depolymerization ; GO:0030835').									biological_process											owl:Class	
GO:0060971	biolink:NamedThing	embryonic heart tube left/right pattern formation	The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.	got7fsn_ti							dph	2009-10-06T10:22:11Z						biological_process											owl:Class	
GO:0005335	biolink:NamedThing	serotonin:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in).	got7fsn_ti	serotonin transmembrane transporter activity|serotonin:sodium:chloride symporter activity|sodium/serotonin symporter activity										GO:0015222|GO:0005336	Reactome:R-HSA-444008|RHEA:51196		molecular_function											owl:Class	
GO:1904347	biolink:NamedThing	regulation of small intestine smooth muscle contraction	Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction.	got7fsn_ti							sl	2015-06-11T21:37:34Z						biological_process											owl:Class	
GO:0035311	biolink:NamedThing	wing cell fate specification	The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.	got7fsn_ti														biological_process											owl:Class	
GO:1901232	biolink:NamedThing	regulation of convergent extension involved in axis elongation	Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation.	got7fsn_ti							vk	2012-08-07T14:21:46Z						biological_process											owl:Class	
GO:1990251	biolink:NamedThing	nuclear exosome focus	An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome.	got7fsn_ti	Mmi1 nuclear focus|nuclear body	https://github.com/geneontology/go-ontology/issues/19063					al	2013-12-09T12:07:46Z						cellular_component											owl:Class	
GO:0042907	biolink:NamedThing	xanthine transmembrane transporter activity	Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.	got7fsn_ti														molecular_function											owl:Class	
GO:0042906	biolink:NamedThing	xanthine transport	The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.	got7fsn_ti	xanthine transmembrane transport													biological_process											owl:Class	
GO:0035920	biolink:NamedThing	negative regulation of high voltage-gated calcium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.	got7fsn_ti	down-regulation of high voltage-gated calcium channel activity in other organism|inhibition of high voltage-gated calcium channel activity in other organism|negative regulation of high voltage gated calcium channel activity in other organism|negative regulation of high voltage-dependent calcium channel activity in other organism|downregulation of high voltage-gated calcium channel activity in other organism						bf	2011-07-01T12:00:23Z						biological_process											owl:Class	
GO:0003263	biolink:NamedThing	cardioblast proliferation	The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti							dph	2009-10-15T02:13:05Z						biological_process											owl:Class	
GO:1905296	biolink:NamedThing	negative regulation of neural crest cell fate specification	Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification.	got7fsn_ti	inhibition of neural crest cell fate specification|down regulation of neural crest cell fate specification|downregulation of neural crest cell fate specification|down-regulation of neural crest cell fate specification						rl	2016-06-28T15:14:49Z						biological_process											owl:Class	
GO:1903946	biolink:NamedThing	negative regulation of ventricular cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential.	got7fsn_ti	downregulation of ventricular cardiac muscle cell action potential|inhibition of ventricular cardiac muscle cell action potential|down regulation of ventricular cardiac muscle cell action potential|down-regulation of ventricular cardiac muscle cell action potential						nc	2015-02-20T14:31:55Z						biological_process											owl:Class	
GO:0045092	biolink:NamedThing	interleukin-18 receptor complex	A protein complex that binds interleukin-18; comprises an alpha and a beta subunit.	got7fsn_ti	IL-18 receptor complex													cellular_component											owl:Class	
GO:0043589	biolink:NamedThing	skin morphogenesis	The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0035016	biolink:NamedThing	elongation of arista lateral	The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.	got7fsn_ti														biological_process											owl:Class	
GO:0061772	biolink:NamedThing	xenobiotic transport across blood-nerve barrier	The directed movement of a xenobiotic through the blood-nerve barrier.	got7fsn_ti	drug transport across perineurial barrier|drug transport across blood-nerve barrier						dph	2016-07-09T09:59:59Z						biological_process											owl:Class	
GO:1901505	biolink:NamedThing	carbohydrate derivative transmembrane transporter activity	Enables the transfer of carbohydrate derivative from one side of a membrane to the other.	got7fsn_ti	carbohydrate derivative transporter activity						pr	2012-10-17T10:31:22Z						molecular_function											owl:Class	
GO:1901264	biolink:NamedThing	carbohydrate derivative transport	The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							bf	2012-08-16T14:51:22Z						biological_process											owl:Class	
GO:0055009	biolink:NamedThing	atrial cardiac muscle tissue morphogenesis	The process in which the anatomical structure of cardiac atrium muscle is generated and organized.	got7fsn_ti	atrial myocardium morphogenesis|atrial heart muscle morphogenesis|cardiac atrium muscle morphogenesis													biological_process											owl:Class	
GO:0046606	biolink:NamedThing	negative regulation of centrosome cycle	Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle.	got7fsn_ti	inhibition of centrosome cycle|down-regulation of centrosome cycle|downregulation of centrosome cycle|down regulation of centrosome cycle													biological_process											owl:Class	
GO:0008622	biolink:NamedThing	epsilon DNA polymerase complex	A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.	got7fsn_ti	DNA polymerase epsilon complex													cellular_component											owl:Class	
GO:2000262	biolink:NamedThing	positive regulation of blood coagulation, common pathway	Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway.	got7fsn_ti							mah	2010-11-23T11:42:48Z						biological_process											owl:Class	
GO:0015578	biolink:NamedThing	mannose transmembrane transporter activity	Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.	got7fsn_ti	mannose permease activity										GO:0015589			molecular_function											owl:Class	
GO:0015761	biolink:NamedThing	mannose transmembrane transport	The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.	got7fsn_ti	mannose transport													biological_process											owl:Class	
GO:0042532	biolink:NamedThing	negative regulation of tyrosine phosphorylation of STAT protein	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	got7fsn_ti	inhibition of tyrosine phosphorylation of Stat6 protein|down-regulation of tyrosine phosphorylation of Stat3 protein|down regulation of tyrosine phosphorylation of Stat3 protein|down regulation of tyrosine phosphorylation of Stat6 protein|negative regulation of tyrosine phosphorylation of Stat7 protein|negative regulation of tyrosine phosphorylation of Stat2 protein|inhibition of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of Stat4 protein|down regulation of tyrosine phosphorylation of Stat2 protein|inhibition of tyrosine phosphorylation of Stat7 protein|inhibition of tyrosine phosphorylation of Stat4 protein|negative regulation of tyrosine phosphorylation of Stat6 protein|down-regulation of tyrosine phosphorylation of Stat5 protein|inhibition of tyrosine phosphorylation of Stat5 protein|down regulation of tyrosine phosphorylation of Stat4 protein|down regulation of tyrosine phosphorylation of Stat7 protein|down regulation of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of Stat2 protein|downregulation of tyrosine phosphorylation of STAT protein|downregulation of tyrosine phosphorylation of Stat3 protein|down-regulation of tyrosine phosphorylation of Stat6 protein|downregulation of tyrosine phosphorylation of Stat6 protein|negative regulation of tyrosine phosphorylation of Stat4 protein|negative regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of tyrosine phosphorylation of Stat3 protein|down-regulation of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of Stat1 protein|down-regulation of tyrosine phosphorylation of Stat4 protein|down regulation of tyrosine phosphorylation of STAT protein|downregulation of tyrosine phosphorylation of Stat7 protein|inhibition of tyrosine phosphorylation of Stat3 protein|down regulation of tyrosine phosphorylation of Stat5 protein|inhibition of tyrosine phosphorylation of Stat2 protein|down-regulation of tyrosine phosphorylation of Stat7 protein|inhibition of tyrosine phosphorylation of STAT protein|negative regulation of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of Stat5 protein|down-regulation of tyrosine phosphorylation of STAT protein|down-regulation of tyrosine phosphorylation of Stat2 protein										GO:0042530|GO:0042521|GO:0042524|GO:0042527|GO:0042514|GO:0042518|GO:0042512			biological_process											owl:Class	
GO:0002070	biolink:NamedThing	epithelial cell maturation	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.	got7fsn_ti														biological_process											owl:Class	
GO:1900259	biolink:NamedThing	regulation of RNA-directed 5'-3' RNA polymerase activity	Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.	got7fsn_ti	regulation of ribonucleic acid replicase activity|regulation of transcriptase|regulation of ribonucleic replicase activity|regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|regulation of RNA synthetase activity|regulation of RNA replicase activity|regulation of Q-beta replicase activity|regulation of PB1 proteins|regulation of RNA-dependent RNA polymerase activity|regulation of RNA-dependent RNA replicase activity|regulation of phage f2 replicase|regulation of RDRP|regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|regulation of PB2 proteins|regulation of RNA-directed RNA polymerase activity|regulation of RNA nucleotidyltransferase (RNA-directed) activity|regulation of 3D polymerase activity|regulation of polymerase L|regulation of ribonucleic synthetase activity|regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity						tb	2012-04-03T11:01:53Z						biological_process											owl:Class	
GO:1905941	biolink:NamedThing	positive regulation of gonad development	Any process that activates or increases the frequency, rate or extent of gonad development.	got7fsn_ti	up-regulation of gonad development|activation of gonadogenesis|upregulation of gonad development|positive regulation of gonadogenesis|up-regulation of gonadogenesis|up regulation of gonadogenesis|activation of gonad development|upregulation of gonadogenesis|up regulation of gonad development						hbye	2017-02-09T17:02:08Z						biological_process											owl:Class	
GO:0016082	biolink:NamedThing	synaptic vesicle priming	A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane.	got7fsn_ti					Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission.  (dos, pvn, fk synapse project 2015)									biological_process											owl:Class	
GO:0075188	biolink:NamedThing	regulation of hyphopodium formation	Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of hyphopodium formation on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0040016	biolink:NamedThing	embryonic cleavage	The first few specialized divisions of an activated animal egg.	got7fsn_ti														biological_process											owl:Class	
GO:0015243	biolink:NamedThing	cycloheximide transmembrane transporter activity	Enables the transfer of cycloheximide from one side of a membrane to the other.  Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.	got7fsn_ti	cycloheximide transporter activity													molecular_function											owl:Class	
GO:0015901	biolink:NamedThing	cycloheximide transport	The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.	got7fsn_ti														biological_process											owl:Class	
GO:0035278	biolink:NamedThing	miRNA mediated inhibition of translation	The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.	got7fsn_ti	down regulation of translation involved in gene silencing by miRNA|downregulation of translation involved in gene silencing by miRNA|down-regulation of translation involved in gene silencing by miRNA|miRNA-mediated gene silencing, negative regulation of translation|gene silencing by miRNA, negative regulation of translation|negative regulation of translation involved in gene silencing by microRNA|inhibition of translation involved in gene silencing by miRNA													biological_process											owl:Class	
GO:0070239	biolink:NamedThing	regulation of activated T cell autonomous cell death	Any process that modulates the occurrence or rate of activated T cell autonomous cell death.	got7fsn_ti	regulation of activated cell autonomous cell death|regulation of activated T cell apoptosis|regulation of ACAD|regulation of activated T lymphocyte autonomous cell death|regulation of activated T-lymphocyte autonomous cell death|regulation of activated T-cell autonomous cell death													biological_process											owl:Class	
GO:2000266	biolink:NamedThing	regulation of blood coagulation, intrinsic pathway	Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway.	got7fsn_ti							mah	2010-11-23T11:45:40Z						biological_process											owl:Class	
GO:0140275	biolink:NamedThing	MIB complex	A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1.	got7fsn_ti	mitochondrial intermembrane space bridging complex|mitofilin complex						pg	2018-10-01T17:10:27Z						cellular_component											owl:Class	
GO:0031305	biolink:NamedThing	integral component of mitochondrial inner membrane	The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to mitochondrial inner membrane													cellular_component											owl:Class	
GO:0046545	biolink:NamedThing	development of primary female sexual characteristics	The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0021720	biolink:NamedThing	superior olivary nucleus formation	The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	got7fsn_ti														biological_process											owl:Class	
GO:0097410	biolink:NamedThing	hippocampal interneuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.	got7fsn_ti							pr	2012-11-04T10:58:28Z						biological_process											owl:Class	
GO:0000353	biolink:NamedThing	formation of quadruple SL/U4/U5/U6 snRNP	Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.	got7fsn_ti					Note that this step is analogous to 5' splice site selection in cis-splicing.									biological_process											owl:Class	
GO:0045291	biolink:NamedThing	mRNA trans splicing, SL addition	The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body.	got7fsn_ti	nuclear mRNA trans splicing, SL addition|nuclear mRNA trans splicing, spliced leader addition													biological_process											owl:Class	
GO:0021901	biolink:NamedThing	early neuron fate commitment in forebrain	The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0006782	biolink:NamedThing	protoporphyrinogen IX biosynthetic process	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.	got7fsn_ti	protoporphyrinogen IX synthesis|protoporphyrinogen IX biosynthesis|protoporphyrinogen IX formation|protoporphyrinogen IX anabolism													biological_process											owl:Class	
GO:0000731	biolink:NamedThing	DNA synthesis involved in DNA repair	Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.	got7fsn_ti	mitotic DNA repair synthesis|DNA synthesis during DNA repair|DNA repair synthesis													biological_process											owl:Class	
GO:0015014	biolink:NamedThing	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.	got7fsn_ti	heparan sulfate proteoglycan chain elongation|heparan sulfate proteoglycan formation, polysaccharide chain biosynthesis|heparan sulfate proteoglycan anabolism, polysaccharide chain anabolism|heparin proteoglycan biosynthetic process, polysaccharide chain biosynthetic process|heparan sulfate proteoglycan formation, polysaccharide chain formation|heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|heparan sulfate proteoglycan synthesis, polysaccharide chain synthesis													biological_process											owl:Class	
GO:0015898	biolink:NamedThing	amiloride transport	The directed movement amiloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.	got7fsn_ti														biological_process											owl:Class	
GO:0035094	biolink:NamedThing	response to nicotine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0002044	biolink:NamedThing	blood vessel endothelial cell migration involved in intussusceptive angiogenesis	The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:1904857	biolink:NamedThing	regulation of endothelial cell chemotaxis to vascular endothelial growth factor	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.	got7fsn_ti							rph	2015-12-16T11:47:44Z						biological_process											owl:Class	
GO:0000086	biolink:NamedThing	G2/M transition of mitotic cell cycle	The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.	got7fsn_ti	mitotic G2/M transition													biological_process											owl:Class	
GO:0099604	biolink:NamedThing	ligand-gated calcium channel activity	Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0048081	biolink:NamedThing	positive regulation of cuticle pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.	got7fsn_ti	upregulation of cuticle pigmentation|stimulation of cuticle pigmentation|up-regulation of cuticle pigmentation|activation of cuticle pigmentation|up regulation of cuticle pigmentation													biological_process											owl:Class	
GO:0048499	biolink:NamedThing	synaptic vesicle membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle.	got7fsn_ti	SLMV biogenesis|synaptic vesicle membrane organization and biogenesis|synaptic vesicle membrane organisation													biological_process											owl:Class	
GO:0021641	biolink:NamedThing	trochlear nerve structural organization	The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	got7fsn_ti	CN IV structural organization|trochlear nerve structural organisation													biological_process											owl:Class	
GO:0110164	biolink:NamedThing	positive regulation of mitotic spindle elongation (spindle phase three)	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three).	got7fsn_ti							kmv	2019-08-12T15:32:20Z						biological_process											owl:Class	
GO:1900727	biolink:NamedThing	osmoregulated periplasmic glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan.	got7fsn_ti	osmoregulated periplasmic glucan anabolism|osmoregulated periplasmic glucan biosynthesis|osmoregulated periplasmic glucan synthesis|osmoregulated periplasmic glucan formation						jl	2012-05-24T03:19:02Z						biological_process											owl:Class	
GO:1904746	biolink:NamedThing	negative regulation of apoptotic process involved in development	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.	got7fsn_ti	downregulation of induction of apoptosis involved in development of an anatomical structure|negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure|inhibition of induction of apoptosis involved in development of an anatomical structure|down-regulation of apoptotic program involved in anatomical structure development|inhibition of apoptotic process involved in development|downregulation of apoptotic programmed cell death involved in development of an anatomical structure|down regulation of activation of apoptosis involved in development of an anatomical structure|inhibition of apoptosis activator activity involved in development of an anatomical structure|down regulation of apoptotic process involved in anatomical structure development|down regulation of apoptosis activator activity involved in anatomical structure development|down regulation of commitment to apoptosis involved in anatomical structure development|negative regulation of induction of apoptosis involved in anatomical structure development|down-regulation of induction of apoptosis involved in anatomical structure development|down regulation of type I programmed cell death involved in development of an anatomical structure|down regulation of programmed cell death by apoptosis involved in anatomical structure development|downregulation of induction of apoptosis involved in anatomical structure development|down-regulation of commitment to apoptosis involved in development of an anatomical structure|inhibition of apoptosis involved in anatomical structure development|negative regulation of commitment to apoptosis involved in development of an anatomical structure|downregulation of apoptotic cell death involved in development of an anatomical structure|negative regulation of type I programmed cell death involved in anatomical structure development|inhibition of apoptotic program involved in anatomical structure development|down regulation of apoptosis signaling involved in anatomical structure development|inhibition of apoptotic process involved in development of an anatomical structure|inhibition of apoptosis signaling involved in anatomical structure development|negative regulation of apoptosis involved in anatomical structure development|inhibition of apoptosis involved in development of an anatomical structure|inhibition of type I programmed cell death involved in anatomical structure development|down regulation of type I programmed cell death involved in anatomical structure development|inhibition of apoptotic cell death involved in development of an anatomical structure|negative regulation of apoptotic cell death involved in anatomical structure development|down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure|inhibition of programmed cell death by apoptosis involved in development of an anatomical structure|downregulation of apoptotic program involved in development of an anatomical structure|negative regulation of apoptosis activator activity involved in anatomical structure development|downregulation of apoptotic cell death involved in anatomical structure development|down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down-regulation of apoptotic process involved in development|down regulation of apoptotic program involved in anatomical structure development|downregulation of apoptosis activator activity involved in anatomical structure development|downregulation of induction of apoptosis by p53 involved in anatomical structure development|negative regulation of induction of apoptosis involved in development of an anatomical structure|inhibition of apoptotic process involved in anatomical structure development|negative regulation of apoptosis signaling involved in development of an anatomical structure|negative regulation of apoptosis signaling involved in anatomical structure development|down regulation of induction of apoptosis involved in development of an anatomical structure|down regulation of signaling (initiator) caspase activity involved in anatomical structure development|negative regulation of apoptosis activator activity involved in development of an anatomical structure|downregulation of apoptotic process involved in development|down-regulation of activation of apoptosis involved in development of an anatomical structure|down-regulation of apoptosis signaling involved in development of an anatomical structure|down regulation of apoptotic programmed cell death involved in anatomical structure development|negative regulation of type I programmed cell death involved in development of an anatomical structure|down-regulation of type I programmed cell death involved in development of an anatomical structure|down regulation of activation of apoptosis involved in anatomical structure development|negative regulation of apoptotic process involved in anatomical structure development|down-regulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of apoptotic programmed cell death involved in development of an anatomical structure|inhibition of type I programmed cell death involved in development of an anatomical structure|downregulation of type I programmed cell death involved in anatomical structure development|down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure|negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure|downregulation of signaling (initiator) caspase activity involved in anatomical structure development|downregulation of apoptotic program involved in anatomical structure development|downregulation of apoptotic process involved in anatomical structure development|inhibition of activation of apoptosis involved in development of an anatomical structure|down regulation of induction of apoptosis by p53 involved in anatomical structure development|inhibition of induction of apoptosis by p53 involved in anatomical structure development|downregulation of commitment to apoptosis involved in anatomical structure development|downregulation of programmed cell death by apoptosis involved in anatomical structure development|downregulation of commitment to apoptosis involved in development of an anatomical structure|negative regulation of apoptotic program involved in development of an anatomical structure|negative regulation of apoptotic process involved in development of an anatomical structure|negative regulation of apoptotic cell death involved in development of an anatomical structure|down regulation of apoptosis signaling involved in development of an anatomical structure|down regulation of apoptotic program involved in development of an anatomical structure|inhibition of activation of apoptosis involved in anatomical structure development|inhibition of programmed cell death by apoptosis involved in anatomical structure development|down-regulation of apoptosis activator activity involved in anatomical structure development|inhibition of apoptosis signaling involved in development of an anatomical structure|negative regulation of apoptosis involved in development of an anatomical structure|inhibition of signaling (initiator) caspase activity involved in anatomical structure development|down-regulation of signaling (initiator) caspase activity involved in anatomical structure development|negative regulation of activation of apoptosis involved in development of an anatomical structure|negative regulation of commitment to apoptosis involved in anatomical structure development|negative regulation of signaling (initiator) caspase activity involved in anatomical structure development|negative regulation of programmed cell death by apoptosis involved in anatomical structure development|down regulation of apoptosis involved in development of an anatomical structure|down-regulation of activation of apoptosis involved in anatomical structure development|down-regulation of commitment to apoptosis involved in anatomical structure development|down regulation of apoptotic programmed cell death involved in development of an anatomical structure|negative regulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of apoptosis activator activity involved in development of an anatomical structure|downregulation of apoptotic process involved in development of an anatomical structure|downregulation of programmed cell death by apoptosis involved in development of an anatomical structure|downregulation of apoptosis signaling involved in development of an anatomical structure|down-regulation of apoptotic cell death involved in anatomical structure development|inhibition of apoptotic cell death involved in anatomical structure development|down-regulation of apoptosis signaling involved in anatomical structure development|inhibition of induction of apoptosis by p53 involved in development of an anatomical structure|downregulation of apoptosis involved in anatomical structure development|down-regulation of programmed cell death by apoptosis involved in anatomical structure development|down-regulation of apoptotic cell death involved in development of an anatomical structure|inhibition of apoptotic programmed cell death involved in development of an anatomical structure|downregulation of apoptosis signaling involved in anatomical structure development|down regulation of programmed cell death by apoptosis involved in development of an anatomical structure|downregulation of activation of apoptosis involved in development of an anatomical structure|down regulation of apoptotic process involved in development|negative regulation of apoptotic program involved in anatomical structure development|down regulation of apoptosis involved in anatomical structure development|down-regulation of apoptotic program involved in development of an anatomical structure|downregulation of type I programmed cell death involved in development of an anatomical structure|downregulation of activation of apoptosis involved in anatomical structure development|downregulation of induction of apoptosis by p53 involved in development of an anatomical structure|inhibition of apoptotic programmed cell death involved in anatomical structure development|down-regulation of apoptotic process involved in development of an anatomical structure|negative regulation of apoptotic programmed cell death involved in development of an anatomical structure|down regulation of commitment to apoptosis involved in development of an anatomical structure|down-regulation of induction of apoptosis involved in development of an anatomical structure|down-regulation of induction of apoptosis by p53 involved in anatomical structure development|downregulation of apoptosis involved in development of an anatomical structure|down regulation of induction of apoptosis by p53 involved in development of an anatomical structure|down-regulation of apoptosis involved in anatomical structure development|down regulation of apoptosis activator activity involved in development of an anatomical structure|downregulation of apoptosis activator activity involved in development of an anatomical structure|inhibition of induction of apoptosis involved in anatomical structure development|down regulation of apoptotic cell death involved in development of an anatomical structure|down regulation of induction of apoptosis involved in anatomical structure development|negative regulation of activation of apoptosis involved in anatomical structure development|inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure|down-regulation of apoptosis involved in development of an anatomical structure|down regulation of apoptotic cell death involved in anatomical structure development|inhibition of apoptotic program involved in development of an anatomical structure|inhibition of commitment to apoptosis involved in anatomical structure development|down regulation of apoptotic process involved in development of an anatomical structure|negative regulation of induction of apoptosis by p53 involved in anatomical structure development|inhibition of apoptosis activator activity involved in anatomical structure development|inhibition of commitment to apoptosis involved in development of an anatomical structure|downregulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down-regulation of type I programmed cell death involved in anatomical structure development|down-regulation of apoptotic process involved in anatomical structure development|downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure|negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure				U4PR86 in PMID:22801495 inferred from mutant phenotype		es	2015-10-19T14:12:27Z						biological_process											owl:Class	
GO:0070560	biolink:NamedThing	protein secretion by platelet	The regulated release of proteins by a platelet or group of platelets.	got7fsn_ti							mah	2009-04-09T02:38:05Z						biological_process											owl:Class	
GO:0002806	biolink:NamedThing	negative regulation of antimicrobial peptide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis.	got7fsn_ti	down-regulation of antimicrobial peptide biosynthetic process|down regulation of antimicrobial peptide biosynthetic process|downregulation of antimicrobial peptide biosynthetic process|inhibition of antimicrobial peptide biosynthetic process													biological_process											owl:Class	
GO:0002929	biolink:NamedThing	MECO complex	A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II.	got7fsn_ti	meta-coactivator complex						hjd	2012-03-14T02:50:13Z						cellular_component											owl:Class	
GO:0010657	biolink:NamedThing	muscle cell apoptotic process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.	got7fsn_ti	muscle cell apoptosis													biological_process											owl:Class	
GO:0042951	biolink:NamedThing	arbutin transmembrane transporter activity	Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042949	biolink:NamedThing	arbutin transport	The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1901235	biolink:NamedThing	(R)-carnitine transmembrane transporter activity	Enables the transfer of (R)-carnitine from one side of a membrane to the other.	got7fsn_ti							jl	2012-08-07T14:46:17Z				RHEA:34959		molecular_function											owl:Class	
GO:1902270	biolink:NamedThing	(R)-carnitine transmembrane transport	The process in which (R)-carnitine is transported across a membrane.	got7fsn_ti							mcc	2013-06-28T21:57:39Z						biological_process											owl:Class	
GO:0099530	biolink:NamedThing	G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential	A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane.	got7fsn_ti	G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential													molecular_function											owl:Class	
GO:0022024	biolink:NamedThing	BMP signaling pathway involved in forebrain neuron fate commitment	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	got7fsn_ti	bone morphogenetic protein signalling pathway involved in forebrain neuron fate commitment|BMP signalling pathway involved in forebrain neuron fate commitment|bone morphogenetic protein signaling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0033168	biolink:NamedThing	conversion of ds siRNA to ss siRNA involved in RNA interference	The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference.	got7fsn_ti	RNA interference, conversion of ds siRNA to ss siRNA													biological_process											owl:Class	
GO:0005788	biolink:NamedThing	endoplasmic reticulum lumen	The volume enclosed by the membranes of the endoplasmic reticulum.	got7fsn_ti	ER lumen|endoplasmic reticulum cisterna|ER cisterna|cisternal lumen										GO:0016022			cellular_component											owl:Class	
GO:0030998	biolink:NamedThing	linear element	A proteinaceous scaffold associated with fission yeast chromosomes during meiotic prophase. Linear elements consist of a protein complex, LinE, with four main structural components (Rec10, Rec25, Rec27, and Mug20 in S. pombe) associated with chromatin. The resulting structure is related to but not equivalent to the synaptonemal complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0004878	biolink:NamedThing	complement component C5a receptor activity	Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	C5a anaphylatoxin receptor activity										GO:0004944			molecular_function											owl:Class	
GO:1901017	biolink:NamedThing	negative regulation of potassium ion transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity.	got7fsn_ti	inhibition of potassium transporter activity|negative regulation of potassium transporter activity|downregulation of potassium transporter activity|down-regulation of potassium ion transmembrane transporter activity|inhibition of potassium ion transmembrane transporter activity|down-regulation of potassium transporter activity|down regulation of potassium transporter activity|down regulation of potassium ion transmembrane transporter activity|downregulation of potassium ion transmembrane transporter activity						rl	2012-06-15T01:14:10Z						biological_process											owl:Class	
GO:0110073	biolink:NamedThing	regulation of apical constriction involved in ventral furrow formation	Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation.	got7fsn_ti							kmv	2017-12-06T17:30:29Z						biological_process											owl:Class	
GO:0015227	biolink:NamedThing	acyl carnitine transmembrane transporter activity	Enables the transfer of acyl carnitine from one side of a membrane to the other. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.	got7fsn_ti	acylcarnitine transporter activity											Reactome:R-HSA-200424		molecular_function											owl:Class	
GO:1902616	biolink:NamedThing	acyl carnitine transmembrane transport	The process in which acyl carnitine is transported across a membrane.	got7fsn_ti	O-acylcarnitine transmembrane transport						pr	2014-01-10T11:07:30Z						biological_process											owl:Class	
GO:0003362	biolink:NamedThing	noradrenergic neuron fate commitment involved in brainstem development	The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem.	got7fsn_ti							dph	2009-12-03T10:56:16Z						biological_process											owl:Class	
GO:0003361	biolink:NamedThing	noradrenergic neuron differentiation involved in brainstem development	The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.	got7fsn_ti							dph	2009-12-03T10:53:30Z						biological_process											owl:Class	
GO:0031663	biolink:NamedThing	lipopolysaccharide-mediated signaling pathway	A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.	got7fsn_ti	lipopolysaccharide-mediated signalling pathway|LPS-mediated signaling pathway													biological_process											owl:Class	
GO:0071222	biolink:NamedThing	cellular response to lipopolysaccharide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.	got7fsn_ti	cellular response to LPS|cellular response to endotoxin						mah	2009-12-03T01:29:29Z						biological_process											owl:Class	
GO:0048341	biolink:NamedThing	paraxial mesoderm formation	The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	got7fsn_ti														biological_process											owl:Class	
GO:0009506	biolink:NamedThing	plasmodesma	A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.	got7fsn_ti	plasmodesmata											Wikipedia:Plasmodesma		cellular_component											owl:Class	
GO:0045254	biolink:NamedThing	pyruvate dehydrogenase complex	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3).	got7fsn_ti	pyruvate dehydrogenase complex (lipoamide)|dihydrolipoyl dehydrogenase complex				Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.						GO:0009364	Wikipedia:Pyruvate_dehydrogenase_complex		cellular_component											owl:Class	
GO:0098689	biolink:NamedThing	latency-replication decision	The process by which a virus switches on its replication cycle in an infected cell.   The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli.	got7fsn_ti	lytic switch|Latency-replication switch|proviral induction|reactivation of latent virus|proviral switch|prophage induction						dos	2017-02-28T11:24:26Z				VZ:3964		biological_process											owl:Class	
GO:0098965	biolink:NamedThing	extracellular matrix of synaptic cleft	The portion of the extracellular matrix that lies within the synaptic cleft.	got7fsn_ti	ECM of synaptic cleft|synaptic cleft ECM													cellular_component											owl:Class	
GO:0032186	biolink:NamedThing	cellular bud neck septin ring organization	Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.	got7fsn_ti	cellular bud neck septin ring organisation													biological_process											owl:Class	
GO:0007105	biolink:NamedThing	cytokinesis, site selection	The process of marking the place where cytokinesis will occur.	got7fsn_ti	site selection involved in cell cycle cytokinesis|site selection involved in cytokinesis										GO:0010687			biological_process											owl:Class	
CL:0000542	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901398	biolink:NamedThing	regulation of transforming growth factor beta3 activation	Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation.	got7fsn_ti	regulation of TGFB3 activation|regulation of TGF-beta 3 activation|regulation of TGFbeta 3 activation						bf	2012-10-01T10:49:25Z						biological_process											owl:Class	
GO:0003127	biolink:NamedThing	detection of nodal flow	The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry.	got7fsn_ti							tb	2009-09-22T02:45:48Z						biological_process											owl:Class	
GO:0030128	biolink:NamedThing	clathrin coat of endocytic vesicle	A clathrin coat found on an endocytic vesicle.	got7fsn_ti	clathrin coat of endocytotic vesicle													cellular_component											owl:Class	
GO:0032391	biolink:NamedThing	photoreceptor connecting cilium	The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.	got7fsn_ti	photoreceptor cilium													cellular_component											owl:Class	
GO:0099606	biolink:NamedThing	microtubule plus-end directed mitotic chromosome migration	The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.	got7fsn_ti	plus-end directed chromosome gliding													biological_process											owl:Class	
GO:1904732	biolink:NamedThing	regulation of electron transfer activity	Any process that modulates the frequency, rate or extent of electron transfer activity.	got7fsn_ti	regulation of amicyanin|regulation of electron transfer flavoprotein, group I|regulation of electron transfer flavoprotein|regulation of iron-sulfur electron transfer carrier|regulation of azurin|regulation of electron donor activity|regulation of electron transfer flavoprotein, group II|regulation of electron carrier, chlorophyll electron transport system|regulation of thioredoxin-like 2Fe-2S ferredoxin|regulation of 2Fe-2S electron transfer carrier|regulation of copper electron carrier|regulation of dicluster bacterial-type ferredoxin|regulation of adrenodoxin-type ferredoxin|regulation of redox-active disulfide bond electron carrier|regulation of chloroplast-type ferredoxin|regulation of rubredoxin|regulation of mononuclear iron electron carrier|regulation of monocluster bacterial-type ferredoxin|regulation of bacterial-type ferredoxin|regulation of high-potential iron-sulfur carrier|regulation of electron transporter activity|regulation of polyferredoxin|regulation of electron acceptor activity|regulation of small blue copper electron carrier|regulation of 3Fe-4S/4Fe-4S electron transfer carrier						lb	2015-10-15T07:51:19Z						biological_process											owl:Class	
GO:1903464	biolink:NamedThing	negative regulation of mitotic cell cycle DNA replication	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.	got7fsn_ti	down regulation of DNA replication involved in S phase involved in mitotic cell cycle|inhibition of mitotic cell cycle DNA replication|negative regulation of DNA replication involved in S phase involved in mitotic cell cycle|down regulation of mitotic nuclear cell cycle DNA replication|inhibition of DNA replication during S phase involved in mitotic cell cycle|down-regulation of DNA replication during S phase involved in mitotic cell cycle|negative regulation of DNA replication involved in S-phase involved in mitotic cell cycle|down-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down-regulation of mitotic cell cycle DNA replication|inhibition of mitotic nuclear cell cycle DNA replication|down-regulation of mitotic nuclear cell cycle DNA replication|negative regulation of DNA replication during S phase involved in mitotic cell cycle|down-regulation of DNA replication involved in S-phase involved in mitotic cell cycle|down regulation of mitotic cell cycle DNA replication|negative regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|downregulation of mitotic nuclear cell cycle DNA replication|downregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down-regulation of DNA replication involved in S phase involved in mitotic cell cycle|down regulation of DNA replication during S phase involved in mitotic cell cycle|negative regulation of mitotic nuclear cell cycle DNA replication|inhibition of nuclear cell cycle DNA replication involved in mitotic cell cycle|downregulation of DNA replication during S phase involved in mitotic cell cycle|inhibition of DNA replication involved in S phase involved in mitotic cell cycle|down regulation of DNA replication involved in S-phase involved in mitotic cell cycle|downregulation of DNA replication involved in S phase involved in mitotic cell cycle|down regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|inhibition of DNA replication involved in S-phase involved in mitotic cell cycle|downregulation of DNA replication involved in S-phase involved in mitotic cell cycle|downregulation of mitotic cell cycle DNA replication						vw	2014-09-23T13:38:33Z						biological_process											owl:Class	
GO:0046662	biolink:NamedThing	regulation of oviposition	Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.	got7fsn_ti	regulation of post-mating oviposition										GO:0048042			biological_process											owl:Class	
GO:0033283	biolink:NamedThing	ATPase-coupled organic acid transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).	got7fsn_ti	organic acid-transporting ATPase activity|ATP-dependent organic acid transmembrane transporter activity													molecular_function											owl:Class	
GO:1903465	biolink:NamedThing	positive regulation of mitotic cell cycle DNA replication	Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication.	got7fsn_ti	positive regulation of DNA replication involved in S phase involved in mitotic cell cycle|up-regulation of DNA replication during S phase involved in mitotic cell cycle|positive regulation of mitotic nuclear cell cycle DNA replication|up-regulation of mitotic nuclear cell cycle DNA replication|activation of mitotic cell cycle DNA replication|activation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up regulation of DNA replication involved in S-phase involved in mitotic cell cycle|positive regulation of DNA replication involved in S-phase involved in mitotic cell cycle|positive regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|positive regulation of DNA replication during S phase involved in mitotic cell cycle|up regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|upregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|upregulation of mitotic cell cycle DNA replication|up-regulation of mitotic cell cycle DNA replication|up-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up regulation of DNA replication during S phase involved in mitotic cell cycle|up-regulation of DNA replication involved in S phase involved in mitotic cell cycle|upregulation of mitotic nuclear cell cycle DNA replication|up regulation of DNA replication involved in S phase involved in mitotic cell cycle|activation of DNA replication involved in S phase involved in mitotic cell cycle|up regulation of mitotic nuclear cell cycle DNA replication|activation of mitotic nuclear cell cycle DNA replication|upregulation of DNA replication during S phase involved in mitotic cell cycle|activation of DNA replication during S phase involved in mitotic cell cycle|activation of DNA replication involved in S-phase involved in mitotic cell cycle|up-regulation of DNA replication involved in S-phase involved in mitotic cell cycle|up regulation of mitotic cell cycle DNA replication|upregulation of DNA replication involved in S-phase involved in mitotic cell cycle|upregulation of DNA replication involved in S phase involved in mitotic cell cycle						vw	2014-09-23T13:38:41Z						biological_process											owl:Class	
GO:1905138	biolink:NamedThing	positive regulation of viral DNA genome packaging via site-specific sequence recognition	Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.	got7fsn_ti	activation of viral DNA genome packaging via site-specific sequence recognition|up-regulation of viral DNA genome packaging via site-specific sequence recognition|upregulation of viral DNA genome packaging via site-specific sequence recognition|up regulation of viral DNA genome packaging via site-specific sequence recognition						pr	2016-04-13T11:37:22Z						biological_process											owl:Class	
GO:0060099	biolink:NamedThing	regulation of phagocytosis, engulfment	Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	got7fsn_ti														biological_process											owl:Class	
CL:0000899	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000295	biolink:NamedThing	adenine nucleotide transmembrane transporter activity	Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-389652		molecular_function											owl:Class	
GO:0051503	biolink:NamedThing	adenine nucleotide transport	The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1905261	biolink:NamedThing	regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.	got7fsn_ti							se	2016-06-13T20:45:02Z						biological_process											owl:Class	
GO:0007407	biolink:NamedThing	neuroblast activation	A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.	got7fsn_ti											GO:0043351|GO:0043352			biological_process											owl:Class	
GO:0097228	biolink:NamedThing	sperm principal piece	The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.	got7fsn_ti							pr	2012-01-25T01:27:27Z						cellular_component											owl:Class	
GO:0019926	biolink:NamedThing	peptidyl-tryptophan oxidation to tryptophyl quinone	The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine.	got7fsn_ti					See also the biological process term 'peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone ; GO:0018069'.									biological_process											owl:Class	
GO:0080139	biolink:NamedThing	borate efflux transmembrane transporter activity	Enables the transfer of borate from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	boron efflux transmembrane transporter activity						dhl	2009-05-19T04:11:45Z						molecular_function											owl:Class	
GO:0035445	biolink:NamedThing	borate transmembrane transport	The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.	got7fsn_ti	borate membrane transport|boron transmembrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-13T09:24:23Z						biological_process											owl:Class	
GO:0001917	biolink:NamedThing	photoreceptor inner segment	The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.	got7fsn_ti														cellular_component											owl:Class	
GO:0072250	biolink:NamedThing	metanephric glomerular visceral epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	got7fsn_ti	metanephric podocyte cell fate commitment						mah	2010-03-19T03:46:41Z						biological_process											owl:Class	
GO:0019634	biolink:NamedThing	organic phosphonate metabolic process	The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.	got7fsn_ti	organophosphonate metabolic process|phosphonate metabolism													biological_process											owl:Class	
GO:0050775	biolink:NamedThing	positive regulation of dendrite morphogenesis	Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.	got7fsn_ti	up regulation of dendrite morphogenesis|stimulation of dendrite morphogenesis|upregulation of dendrite morphogenesis|up-regulation of dendrite morphogenesis|activation of dendrite morphogenesis													biological_process											owl:Class	
GO:2000634	biolink:NamedThing	regulation of primary miRNA processing	Any process that modulates the frequency, rate or extent of primary microRNA processing.	got7fsn_ti	regulation of primary microRNA processing|regulation of pri-miRNA processing						dph	2011-04-18T03:50:50Z						biological_process											owl:Class	
GO:1901029	biolink:NamedThing	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.	got7fsn_ti	inhibition of MOMP|down-regulation of MOMP|down-regulation of mitochondrial outer membrane permeabilization|down regulation of MOMP|negative regulation of mitochondrial outer membrane permeabilization|down regulation of mitochondrial outer membrane permeabilization|downregulation of MOMP|downregulation of mitochondrial outer membrane permeabilization|negative regulation of MOMP|inhibition of mitochondrial outer membrane permeabilization						pr	2012-06-20T09:19:39Z						biological_process											owl:Class	
GO:0060573	biolink:NamedThing	cell fate specification involved in pattern specification	The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.	got7fsn_ti							dph	2009-05-05T02:19:14Z						biological_process											owl:Class	
GO:0060581	biolink:NamedThing	cell fate commitment involved in pattern specification	The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.	got7fsn_ti							dph	2009-05-07T12:40:55Z						biological_process											owl:Class	
GO:1902941	biolink:NamedThing	regulation of voltage-gated chloride channel activity	Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity.	got7fsn_ti	regulation of voltage-dependent chloride channel activity|regulation of voltage gated chloride channel activity						als	2014-04-28T08:55:31Z						biological_process											owl:Class	
GO:0090725	biolink:NamedThing	peripheral region of growth cone	The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite.	got7fsn_ti							tb	2016-11-18T12:44:25Z						cellular_component											owl:Class	
GO:0031314	biolink:NamedThing	extrinsic component of mitochondrial inner membrane	The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to mitochondrial inner membrane													cellular_component											owl:Class	
GO:0006882	biolink:NamedThing	cellular zinc ion homeostasis	Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.	got7fsn_ti	zinc homeostasis													biological_process											owl:Class	
GO:0140040	biolink:NamedThing	mitochondrial polycistronic RNA processing	The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs.	got7fsn_ti							pg	2017-06-16T07:18:38Z						biological_process											owl:Class	
GO:0021880	biolink:NamedThing	Notch signaling pathway involved in forebrain neuron fate commitment	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	got7fsn_ti	Notch signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0010389	biolink:NamedThing	regulation of G2/M transition of mitotic cell cycle	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.	got7fsn_ti	regulation of mitotic entry													biological_process											owl:Class	
GO:0015199	biolink:NamedThing	amino-acid betaine transmembrane transporter activity	Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid.	got7fsn_ti	glycine betaine/proline porter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|betaine transmembrane transporter activity|betaine/GABA:sodium symporter activity													molecular_function											owl:Class	
GO:0015838	biolink:NamedThing	amino-acid betaine transport	The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	betaine transport													biological_process											owl:Class	
GO:0001942	biolink:NamedThing	hair follicle development	The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.	got7fsn_ti											GO:0001943			biological_process											owl:Class	
GO:0043680	biolink:NamedThing	filiform apparatus	A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells.	got7fsn_ti														cellular_component											owl:Class	
GO:0001772	biolink:NamedThing	immunological synapse	An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.	got7fsn_ti	c-SMAC|supramolecular activation cluster											Wikipedia:Immunological_synapse		cellular_component											owl:Class	
GO:0090210	biolink:NamedThing	regulation of establishment of blood-brain barrier	Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.	got7fsn_ti	regulation of establishment of BBB						tb	2009-12-23T12:15:53Z						biological_process											owl:Class	
GO:0016013	biolink:NamedThing	syntrophin complex	A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase.	got7fsn_ti	nitric oxide synthase-dystrophin complex, skeletal muscle													cellular_component											owl:Class	
GO:0009877	biolink:NamedThing	nodulation	The formation of nitrogen-fixing root nodules on plant roots.	got7fsn_ti	nodule formation|nodule development|nodule morphogenesis	https://github.com/geneontology/go-ontology/issues/20305									GO:0009878			biological_process											owl:Class	
GO:0030235	biolink:NamedThing	nitric-oxide synthase regulator activity	Binds to and modulates the activity of nitric oxide synthase.	got7fsn_ti	nitric oxide synthase regulator activity				See also 'regulation of nitric-oxide synthase activity ; GO:0050999'.									molecular_function											owl:Class	
GO:0046854	biolink:NamedThing	phosphatidylinositol phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate.	got7fsn_ti	PIP biosynthesis|phosphatidylinositol phosphate biosynthesis|phosphoinositide phosphorylation|PtdInsP biosynthesis|phosphatidylinositol phosphate phosphorylation|phosphatidylinositol phosphate biosynthetic process|phosphatidylinositol phosphorylation	https://github.com/geneontology/go-ontology/issues/14184									GO:0046837			biological_process											owl:Class	
GO:0055018	biolink:NamedThing	regulation of cardiac muscle fiber development	Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.	got7fsn_ti	regulation of heart muscle fiber development|regulation of cardiac muscle fibre development													biological_process											owl:Class	
GO:1903400	biolink:NamedThing	L-arginine transmembrane transport	The directed movement of L-arginine across a membrane.	got7fsn_ti							pr	2014-09-01T13:45:48Z						biological_process											owl:Class	
GO:0044226	biolink:NamedThing	basal pole of neuron	Portion of a neuron cell soma closest to the point where the basilar dendrite emerges.	got7fsn_ti							jl	2009-11-13T04:32:17Z				NIF_Subcellular:sao1186862860		cellular_component											owl:Class	
GO:1902667	biolink:NamedThing	regulation of axon guidance	Any process that modulates the frequency, rate or extent of axon guidance.	got7fsn_ti	regulation of axon pathfinding|regulation of axon growth cone guidance|regulation of axon chemotaxis						hjd	2014-01-31T18:50:10Z						biological_process											owl:Class	
GO:1902671	biolink:NamedThing	left anterior basal body	Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage).	got7fsn_ti	ciliary basal body of left anterior flagellum|cilial basal body of left anterior flagellum|microtubule basal body of left anterior flagellum|ciliary basal body of left anterior cilium|cilium basal body of left anterior cilium|left anterior flagellum ciliary basal body|microtubule basal body of left anterior cilium|cilial basal body of left anterior cilium|cilium basal body of left anterior flagellum				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:28:44Z						cellular_component											owl:Class	
GO:0003228	biolink:NamedThing	atrial cardiac muscle tissue development	The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.	got7fsn_ti	atrial myocardium development						dph	2009-10-13T10:53:18Z						biological_process											owl:Class	
GO:0060299	biolink:NamedThing	negative regulation of sarcomere organization	Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	got7fsn_ti	negative regulation of sarcomere organisation													biological_process											owl:Class	
GO:0035631	biolink:NamedThing	CD40 receptor complex	A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules.	got7fsn_ti							bf	2010-12-21T10:35:05Z						cellular_component											owl:Class	
GO:1904977	biolink:NamedThing	lymphatic endothelial cell migration	The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel.	got7fsn_ti							dgh	2016-02-18T20:49:43Z						biological_process											owl:Class	
GO:0071074	biolink:NamedThing	eukaryotic initiation factor eIF2 binding	Binding to eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.	got7fsn_ti							mah	2009-11-06T01:39:02Z						molecular_function											owl:Class	
GO:0000242	biolink:NamedThing	pericentriolar material	A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0097555	biolink:NamedThing	right anterior flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell.	got7fsn_ti	right anterior cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:18:36Z						cellular_component											owl:Class	
GO:0002795	biolink:NamedThing	negative regulation of antimicrobial peptide secretion	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.	got7fsn_ti	downregulation of antimicrobial peptide secretion|down-regulation of antimicrobial peptide secretion|inhibition of antimicrobial peptide secretion|down regulation of antimicrobial peptide secretion													biological_process											owl:Class	
GO:0075524	biolink:NamedThing	ribosomal skipping	A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue.	got7fsn_ti					This term is intended to annotate gene products involved in the process of ribosomal skipping, not viral proteins produced by this translation process.		jl	2011-08-03T03:19:37Z				VZ:914		biological_process											owl:Class	
GO:0097716	biolink:NamedThing	copper ion transport across blood-brain barrier	The directed movement of copper (Cu) ions passing through the blood-brain barrier.	got7fsn_ti	copper ion transport across BBB						pr	2016-08-23T14:35:54Z						biological_process											owl:Class	
GO:0030205	biolink:NamedThing	dermatan sulfate metabolic process	The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues.	got7fsn_ti	dermatan sulphate metabolic process|chondroitin sulfate B metabolism|dermatan sulphate metabolism|dermatan sulfate metabolism|chondroitin sulfate B metabolic process													biological_process											owl:Class	
GO:0050655	biolink:NamedThing	dermatan sulfate proteoglycan metabolic process	The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.	got7fsn_ti	dermatan sulfate proteoglycan metabolism|chondroitin sulfate B proteoglycan metabolism|dermatan sulphate proteoglycan metabolic process|dermatan sulphate proteoglycan metabolism|chondroitin sulfate B proteoglycan metabolic process													biological_process											owl:Class	
GO:1903383	biolink:NamedThing	regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.	got7fsn_ti	regulation of hydrogen peroxide-induced neuron apoptosis|regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|regulation of hydrogen peroxide-induced neuronal apoptosis|regulation of neuron apoptosis in response to hydrogen peroxide|regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|regulation of H2O2-induced neuron apoptosis|regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway						bf	2014-08-27T08:50:37Z						biological_process											owl:Class	
GO:0045470	biolink:NamedThing	R8 cell-mediated photoreceptor organization	The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor.	got7fsn_ti	R8-mediated photoreceptor organisation													biological_process											owl:Class	
GO:0051378	biolink:NamedThing	serotonin binding	Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	got7fsn_ti	5-hydroxytryptamine binding													molecular_function											owl:Class	
GO:0044613	biolink:NamedThing	nuclear pore central transport channel	The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.	got7fsn_ti	karyopherin docking complex|nuclear pore central channel|nuclear pore transport channel|nuclear pore central plug						jl	2012-06-20T01:25:30Z						cellular_component											owl:Class	
GO:1903395	biolink:NamedThing	regulation of secondary cell septum biogenesis	Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis.	got7fsn_ti							di	2014-08-29T21:42:17Z						biological_process											owl:Class	
GO:0039018	biolink:NamedThing	nephrostome development	The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.	got7fsn_ti							bf	2010-07-02T10:08:16Z						biological_process											owl:Class	
GO:2001191	biolink:NamedThing	regulation of gamma-delta T cell activation involved in immune response	Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response.	got7fsn_ti	regulation of gamma-delta T-cell activation during immune response|regulation of gamma-delta T lymphocyte activation during immune response|regulation of gamma-delta T-lymphocyte activation during immune response|regulation of gamma-delta T cell activation during immune response						yaf	2011-11-03T04:28:38Z						biological_process											owl:Class	
GO:0044626	biolink:NamedThing	envenomation resulting in positive regulation of cell migration in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of cell migration in the bitten organism.	got7fsn_ti							jl	2012-07-04T05:08:21Z						biological_process											owl:Class	
GO:0010633	biolink:NamedThing	negative regulation of epithelial cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.	got7fsn_ti														biological_process											owl:Class	
GO:0004679	biolink:NamedThing	AMP-activated protein kinase activity	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.	got7fsn_ti	SNF1A/AMP-activated protein kinase activity|AMPK activity|5'-AMP-activated protein kinase activity											Reactome:R-HSA-447074|Reactome:R-HSA-6805470|Reactome:R-HSA-163691|EC:2.7.11.11|Reactome:R-HSA-200423|Reactome:R-HSA-380927|Reactome:R-HSA-1592244|Reactome:R-HSA-5673768		molecular_function											owl:Class	
GO:0016208	biolink:NamedThing	AMP binding	Binding to AMP, adenosine monophosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0086043	biolink:NamedThing	bundle of His cell action potential	An action potential that occurs in a bundle of His cell.	got7fsn_ti	bundle of His cardiac muscle cell action potential						dph	2011-11-15T12:01:18Z						biological_process											owl:Class	
GO:0099012	biolink:NamedThing	neuronal dense core vesicle membrane	The lipid bilayer surrounding a neuronal dense core vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0038117	biolink:NamedThing	C-C motif chemokine 19 receptor activity	Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	CCL19 receptor activity						bf	2012-03-22T11:59:10Z						molecular_function											owl:Class	
GO:0035757	biolink:NamedThing	chemokine (C-C motif) ligand 19 binding	Binding to chemokine (C-C motif) ligand 19.	got7fsn_ti	CCL19 binding						bf	2011-03-25T02:02:36Z						molecular_function											owl:Class	
GO:0072334	biolink:NamedThing	UDP-galactose transmembrane transport	The process in which UDP-galactose is transported across a membrane.	got7fsn_ti	UDP-galactose transport|UDP-galactose membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-11-03T02:03:36Z			GO:0015785			biological_process											owl:Class	
GO:0043317	biolink:NamedThing	regulation of cytotoxic T cell degranulation	Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation.	got7fsn_ti	regulation of cytotoxic T-lymphocyte degranulation|regulation of cytotoxic T-cell degranulation|regulation of cytotoxic T-cell granule exocytosis|regulation of cytotoxic T lymphocyte degranulation|regulation of cytotoxic T lymphocyte granule exocytosis|regulation of cytotoxic T cell granule exocytosis|regulation of cytotoxic T-lymphocyte granule exocytosis													biological_process											owl:Class	
GO:0097217	biolink:NamedThing	sieve area	A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements.	got7fsn_ti					Part of a sieve element (PO:0025406).		pr	2012-01-13T05:39:03Z						cellular_component											owl:Class	
GO:0001876	biolink:NamedThing	lipoarabinomannan binding	Binding to lipoarabinomannan.	got7fsn_ti	LAM binding													molecular_function											owl:Class	
GO:0005658	biolink:NamedThing	alpha DNA polymerase:primase complex	A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a smal stretch of DNA. The smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.	got7fsn_ti	heterotetrameric polymerase alpha holoenzyme|pol-prim|primosome|DNA polymerase alpha:primase complex													cellular_component											owl:Class	
GO:0003887	biolink:NamedThing	DNA-directed DNA polymerase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.	got7fsn_ti	mu DNA polymerase activity|iota DNA polymerase activity|deoxyribonucleic acid duplicase activity|deoxyribonucleic duplicase activity|DNA replicase activity|DNA polymerase alpha|Klenow fragment|deoxyribonucleic polymerase I|beta DNA polymerase activity|kappa DNA polymerase activity|DNA-dependent DNA polymerase activity|DNA polymerase II|epsilon DNA polymerase activity|zeta DNA polymerase activity|DNA polymerase V activity|nu DNA polymerase activity|DNA nucleotidyltransferase (DNA-directed) activity|Tca DNA polymerase|DNA polymerase beta|DNA polymerase III|sequenase|sigma DNA polymerase activity|eta DNA polymerase activity|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|duplicase|DNA polymerase gamma|DNA polymerase I|Taq DNA polymerase|alpha DNA polymerase activity|delta DNA polymerase activity|lambda DNA polymerase activity|Taq Pol I|theta DNA polymerase activity|gamma DNA-directed DNA polymerase activity|DNA duplicase activity										GO:0003894|GO:0016451|GO:0015999|GO:0016449|GO:0003891|GO:0003893|GO:0003888|GO:0008723|GO:0003890|GO:0019984|GO:0016452|GO:0016450|GO:0003895|GO:0016448|GO:0003889|GO:0016000	Reactome:R-HSA-5358579|Reactome:R-HSA-69116|Reactome:R-HSA-5656158|Reactome:R-HSA-5655965|MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN|Reactome:R-HSA-110317|Reactome:R-HSA-174444|Reactome:R-HSA-5691001|Reactome:R-HSA-5649883|Reactome:R-HSA-5649723|Reactome:R-HSA-164505|Reactome:R-HSA-174427|Reactome:R-HSA-73932|Reactome:R-HSA-5687360|Reactome:R-HSA-110368|Reactome:R-HSA-110319|Reactome:R-HSA-110311|Reactome:R-HSA-5656148|Reactome:R-HSA-6782208|Reactome:R-HSA-6786166|EC:2.7.7.7|Reactome:R-HSA-68950|Reactome:R-HSA-164513|Reactome:R-HSA-5693593|Reactome:R-HSA-5687640|Reactome:R-HSA-111253|Reactome:R-HSA-5653840|Reactome:R-HSA-5655892		molecular_function											owl:Class	
GO:1903382	biolink:NamedThing	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.	got7fsn_ti	inhibition of ER stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|down-regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down-regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|downregulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|downregulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|downregulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|inhibition of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|inhibition of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway						bf	2014-08-27T08:45:38Z						biological_process											owl:Class	
GO:0005912	biolink:NamedThing	adherens junction	A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.	got7fsn_ti	cell-cell adherens junction										GO:0005913	Wikipedia:Adherens_junction		cellular_component											owl:Class	
GO:0010183	biolink:NamedThing	pollen tube guidance	The process in which the growth of pollen tube is directed towards the female gametophyte.	got7fsn_ti														biological_process											owl:Class	
GO:0033266	biolink:NamedThing	ABC-type choline transporter activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.	got7fsn_ti	ATP-dependent choline transmembrane transporter activity|ABC-type choline transmembrane transporter activity|ATPase-coupled choline transmembrane transporter activity|choline-transporting ATPase activity													molecular_function											owl:Class	
GO:0015871	biolink:NamedThing	choline transport	The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	got7fsn_ti														biological_process											owl:Class	
GO:0048263	biolink:NamedThing	determination of dorsal identity	Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti	determination of adaxial identity													biological_process											owl:Class	
GO:0007563	biolink:NamedThing	regulation of eclosion	Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg.	got7fsn_ti														biological_process											owl:Class	
GO:1904832	biolink:NamedThing	negative regulation of removal of superoxide radicals	Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals.	got7fsn_ti	down-regulation of removal of superoxide radicals|down regulation of removal of O2-|down-regulation of cellular detoxification of superoxide radicals|down regulation of removal of superoxide radicals|inhibition of removal of superoxide radicals|downregulation of removal of superoxide radicals|inhibition of removal of O2-|down regulation of removal of oxygen free radicals|negative regulation of cellular detoxification of superoxide radicals|negative regulation of removal of oxygen free radicals|inhibition of removal of oxygen free radicals|down regulation of cellular detoxification of superoxide radicals|down-regulation of removal of O2-|downregulation of cellular detoxification of superoxide radicals|negative regulation of removal of O2-|downregulation of removal of O2-|inhibition of cellular detoxification of superoxide radicals|down-regulation of removal of oxygen free radicals|downregulation of removal of oxygen free radicals						rph	2015-11-24T15:30:18Z						biological_process											owl:Class	
GO:0008039	biolink:NamedThing	synaptic target recognition	The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses.	got7fsn_ti	neuronal targeting													biological_process											owl:Class	
GO:0036477	biolink:NamedThing	somatodendritic compartment	The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon.	got7fsn_ti							bf	2014-07-24T10:06:19Z						cellular_component											owl:Class	
GO:1904178	biolink:NamedThing	negative regulation of adipose tissue development	Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development.	got7fsn_ti	negative regulation of adipogenesis|down regulation of adipogenesis|inhibition of adipogenesis|down-regulation of adipogenesis|downregulation of adipogenesis|down regulation of adipose tissue development|downregulation of adipose tissue development|down-regulation of adipose tissue development|inhibition of adipose tissue development						sl	2015-04-29T20:01:07Z						biological_process											owl:Class	
GO:0033381	biolink:NamedThing	establishment of granzyme B localization to T cell secretory granule	The directed movement of the protease granzyme B to a location within a secretory granule in a T cell.	got7fsn_ti	establishment of granzyme B localization in T cell secretory granule|T-lymphocyte secretory granule storage of granzyme B|establishment of granzyme B localization in T-cell secretory granule|establishment of granzyme B localization in T-lymphocyte secretory granule|establishment of granzyme B localisation in T cell secretory granule|establishment of granzyme B localization in T lymphocyte secretory granule													biological_process											owl:Class	
GO:0021722	biolink:NamedThing	superior olivary nucleus maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	got7fsn_ti	superior olive maturation													biological_process											owl:Class	
GO:0021590	biolink:NamedThing	cerebellum maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	got7fsn_ti														biological_process											owl:Class	
GO:0035168	biolink:NamedThing	larval lymph gland hemocyte differentiation	The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	larval lymph gland arthropod blood cell differentiation													biological_process											owl:Class	
GO:0031585	biolink:NamedThing	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.	got7fsn_ti	regulation of inositol-1,4,5-triphosphate receptor activity|regulation of IP3 receptor activity													biological_process											owl:Class	
GO:0070360	biolink:NamedThing	migration of symbiont within host by polymerization of host actin	The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:1905764	biolink:NamedThing	regulation of protection from non-homologous end joining at telomere	Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere.	got7fsn_ti	regulation of protection from NHEJ-mediated telomere fusion						nc	2016-12-20T11:28:21Z						biological_process											owl:Class	
GO:0019819	biolink:NamedThing	P1 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms.	got7fsn_ti	peroxisome vesicle				Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'.									cellular_component											owl:Class	
GO:0035034	biolink:NamedThing	histone acetyltransferase regulator activity	Binds to and modulates the activity of histone acetyltransferase.	got7fsn_ti	histone acetylase regulator activity				See also the molecular function term 'histone acetyltransferase activity ; GO:0004402'.									molecular_function											owl:Class	
GO:0035065	biolink:NamedThing	regulation of histone acetylation	Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.	got7fsn_ti														biological_process											owl:Class	
GO:0048217	biolink:NamedThing	pectic matrix	The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls.	got7fsn_ti														cellular_component											owl:Class	
GO:0009530	biolink:NamedThing	primary cell wall	A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present.	got7fsn_ti														cellular_component											owl:Class	
GO:0001174	biolink:NamedThing	transcriptional start site selection at RNA polymerase II promoter	Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	got7fsn_ti							krc	2011-06-20T01:35:28Z						biological_process											owl:Class	
GO:0098909	biolink:NamedThing	regulation of cardiac muscle cell action potential involved in regulation of contraction	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction.	got7fsn_ti							tb	2011-11-10T07:45:11Z						biological_process											owl:Class	
GO:0015143	biolink:NamedThing	urate transmembrane transporter activity	Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.	got7fsn_ti	uric acid transmembrane transporter activity											Reactome:R-HSA-5625210|Reactome:R-HSA-561253|Reactome:R-HSA-2872497		molecular_function											owl:Class	
GO:0015747	biolink:NamedThing	urate transport	The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	uric acid transport|urate transmembrane transport													biological_process											owl:Class	
GO:0090405	biolink:NamedThing	unicellular trichome branch	A cell projection part that is a branch of a unicellular trichome.	got7fsn_ti					Unicellular trichome (PO:0025537) is a trichome(PO:0000282) that is a single plant cell (PO:0009002). For a cell that forms a branch of a multicellular trichome, see multicellular trichome branch cell (PO:0025163).		tb	2011-01-10T10:30:39Z						cellular_component											owl:Class	
GO:0110159	biolink:NamedThing	regulation of mitotic spindle formation (spindle phase one)	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).	got7fsn_ti							kmv	2019-08-12T15:10:26Z						biological_process											owl:Class	
GO:0032888	biolink:NamedThing	regulation of mitotic spindle elongation	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.	got7fsn_ti														biological_process											owl:Class	
GO:0005951	biolink:NamedThing	carbamoyl-phosphate synthase complex	A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.	got7fsn_ti	arginine-specific carbamoyl phosphate synthetase complex|carbamoyl phosphate synthase complex|carbamoyl-phosphate synthase arginine-specific complex				Note that in higher eukaryotes, carbamoyl-phosphate synthase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term.									cellular_component											owl:Class	
GO:0061296	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.	got7fsn_ti	negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis						dph	2010-09-06T09:54:49Z						biological_process											owl:Class	
GO:1904301	biolink:NamedThing	regulation of maternal process involved in parturition	Any process that modulates the frequency, rate or extent of maternal process involved in parturition.	got7fsn_ti							sl	2015-06-09T23:01:32Z						biological_process											owl:Class	
GO:1990171	biolink:NamedThing	SCF complex disassembly in response to cadmium stress	The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress.	got7fsn_ti							rb	2013-08-15T22:38:06Z						biological_process											owl:Class	
GO:1905823	biolink:NamedThing	negative regulation of mitotic sister chromatid arm separation	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation.	got7fsn_ti	inhibition of mitotic sister chromatid arm separation|down-regulation of mitotic sister chromatid arm separation|down regulation of mitotic sister chromatid arm separation|downregulation of mitotic sister chromatid arm separation						als	2017-01-16T13:36:38Z						biological_process											owl:Class	
GO:1903186	biolink:NamedThing	regulation of vitellogenesis	Any process that modulates the frequency, rate or extent of vitellogenesis.	got7fsn_ti	regulation of yolk production						mr	2014-07-14T19:28:00Z						biological_process											owl:Class	
GO:0015170	biolink:NamedThing	propanediol transmembrane transporter activity	Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.	got7fsn_ti														molecular_function											owl:Class	
GO:0015799	biolink:NamedThing	propanediol transport	The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.	got7fsn_ti														biological_process											owl:Class	
GO:0034496	biolink:NamedThing	multivesicular body membrane disassembly	The controlled breakdown of the membranes of multivesicular bodies.	got7fsn_ti	MVB membrane disassembly													biological_process											owl:Class	
GO:0036257	biolink:NamedThing	multivesicular body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.	got7fsn_ti	MVB organization						bf	2012-06-15T01:09:53Z						biological_process											owl:Class	
GO:1901253	biolink:NamedThing	negative regulation of intracellular transport of viral material	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material.	got7fsn_ti	inhibition of movement of virus within host cell|downregulation of egress of virus within host cell|down regulation of viral egress|inhibition of egress of virus within host cell|negative regulation of movement of virus within host cell|downregulation of viral egress|negative regulation of viral egress|down-regulation of movement of virus within host cell|downregulation of movement of virus within host cell|inhibition of viral egress|down regulation of egress of virus within host cell|down-regulation of viral egress|negative regulation of egress of virus within host cell|down-regulation of egress of virus within host cell|down regulation of movement of virus within host cell						ss	2012-08-09T05:45:47Z						biological_process											owl:Class	
GO:0005055	biolink:NamedThing	laminin receptor activity	Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity.	got7fsn_ti					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'cell adhesion molecule binding ; GO:0050839' and 'receptor binding ; GO:0005102' and the biological process term 'cell adhesion ; GO:0007155'.									molecular_function											owl:Class	
GO:1905824	biolink:NamedThing	positive regulation of mitotic sister chromatid arm separation	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation.	got7fsn_ti	up-regulation of mitotic sister chromatid arm separation|upregulation of mitotic sister chromatid arm separation|up regulation of mitotic sister chromatid arm separation|activation of mitotic sister chromatid arm separation						als	2017-01-16T13:36:47Z						biological_process											owl:Class	
GO:2000469	biolink:NamedThing	negative regulation of peroxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity.	got7fsn_ti	negative regulation of donor:hydrogen-peroxide oxidoreductase activity|negative regulation of peroxidase reaction|negative regulation of oxyperoxidase activity						bf	2011-03-08T02:18:59Z						biological_process											owl:Class	
GO:0030660	biolink:NamedThing	Golgi-associated vesicle membrane	The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.	got7fsn_ti	Golgi vesicle membrane													cellular_component											owl:Class	
GO:0003048	biolink:NamedThing	regulation of systemic arterial blood pressure by norepinephrine	The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine.	got7fsn_ti	regulation of blood pressure by noradrenaline|blood pressure regulation by norepinephrine													biological_process											owl:Class	
GO:1905266	biolink:NamedThing	blasticidin S biosynthetic process	The chemical reactions and pathways resulting in the formation of blasticidin S.	got7fsn_ti	blasticidin S anabolism|blasticidin S synthesis|blasticidin S formation|blasticidin S biosynthesis						pr	2016-06-14T12:47:22Z						biological_process											owl:Class	
GO:0042071	biolink:NamedThing	leucokinin receptor activity	Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0021899	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	got7fsn_ti	fibroblast growth factor receptor signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0000148	biolink:NamedThing	1,3-beta-D-glucan synthase complex	A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.	got7fsn_ti	1,3-beta-glucan synthase complex|(1->3)-beta-glucan synthase complex													cellular_component											owl:Class	
GO:0048915	biolink:NamedThing	posterior lateral line system development	The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.	got7fsn_ti	PLL													biological_process											owl:Class	
GO:0042663	biolink:NamedThing	regulation of endodermal cell fate specification	Any process that mediates the specification of a cell into an endoderm cell.	got7fsn_ti	regulation of endoderm cell fate specification													biological_process											owl:Class	
GO:0015221	biolink:NamedThing	lipopolysaccharide transmembrane transporter activity	Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.	got7fsn_ti	LPS transmembrane transporter activity													molecular_function											owl:Class	
GO:0046868	biolink:NamedThing	mesosome	An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins.	got7fsn_ti												Wikipedia:Mesosome		cellular_component											owl:Class	
GO:0061789	biolink:NamedThing	dense core granule priming	A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking.	got7fsn_ti	large dense-core vesicle priming|LDCV priming|dense core vesicle priming						dph	2016-09-08T15:41:30Z						biological_process											owl:Class	
GO:1990504	biolink:NamedThing	dense core granule exocytosis	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.	got7fsn_ti	dense core vesicle exocytosis						kmv	2014-09-30T21:05:50Z						biological_process											owl:Class	
GO:0007220	biolink:NamedThing	Notch receptor processing	The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.	got7fsn_ti	N receptor processing													biological_process											owl:Class	
GO:0033023	biolink:NamedThing	mast cell homeostasis	The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti					Note that this term represents the return of mast cell levels to stable numbers following an immune response as well as the proliferation and elimination of mast cells required to maintain stable numbers in the absence of an outside stimulus.									biological_process											owl:Class	
GO:0044768	biolink:NamedThing	NMS complex assembly	The aggregation, arrangement and bonding together of a set of components to form an NMS complex. The NMS complex results from the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) and is required for kinetochore assembly.	got7fsn_ti	Ndc80-MIND-Spc7 complex formation|KNL-1-Mis12-Ndc80 assembly|KNL-1-Mis12-Ndc80 formation|NMS complex formation|Ndc80-MIND-Spc7 complex assembly|NMS complex assembly involved in kinetochore assembly|KMN complex interaction involved in chromosome segregation|KMN kinetochore network formation|KMN kinetochore network assembly|KMN network assembly involved in chromosome segregation|NMS complex association involved in chromosome segregation						jl	2012-12-19T14:44:56Z						biological_process											owl:Class	
GO:0006693	biolink:NamedThing	prostaglandin metabolic process	The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.	got7fsn_ti	prostaglandin metabolism													biological_process											owl:Class	
GO:0032936	biolink:NamedThing	SREBP-SCAP complex	A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed.	got7fsn_ti	Sre1-Scp1 complex													cellular_component											owl:Class	
GO:0032775	biolink:NamedThing	DNA methylation on adenine	The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule.	got7fsn_ti	adenine methylation													biological_process											owl:Class	
GO:0015097	biolink:NamedThing	mercury ion transmembrane transporter activity	Enables the transfer of mercury (Hg) ions from one side of a membrane to the other.	got7fsn_ti												RHEA:32815		molecular_function											owl:Class	
GO:0098792	biolink:NamedThing	xenophagy	The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents.	got7fsn_ti					While making xenophagy a subclass of (macro)autophagy may seem to directly contradict the definition of autophagy (literally self eating), it is clear that the same pathway is involved as in macroautophagy that doesn't target foreign material: formation of double-membrane-bounded autophagosomes that enclose a region of cytoplasm for degradation.									biological_process											owl:Class	
GO:0072544	biolink:NamedThing	L-DOPA binding	Binding to L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid.	got7fsn_ti	L-dopa binding						mah	2011-01-19T05:40:04Z						molecular_function											owl:Class	
GO:1905367	biolink:NamedThing	positive regulation of intralumenal vesicle formation	Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation.	got7fsn_ti	positive regulation of endosome membrane budding|up regulation of endosome membrane budding|up-regulation of intralumenal vesicle formation|up regulation of intralumenal vesicle formation|upregulation of endosome membrane budding|up-regulation of endosome membrane budding|activation of intralumenal vesicle formation|activation of endosome membrane budding|upregulation of intralumenal vesicle formation						bc	2016-08-16T12:00:16Z						biological_process											owl:Class	
GO:0097546	biolink:NamedThing	ciliary base	Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.	got7fsn_ti	cilial base|cilium base|flagellum base|flagellar base				Due to resolution issues, researchers are often unable to assign protein localization to more specific ciliary compartments such as the basal body, transition fibers or transition zone, and instead refer to 'ciliary base'. The terms GO:0036064 'ciliary basal body', GO:0097539 'ciliary transition fiber' and GO:0035869 'ciliary transition zone' represent strictly defined compartments at the ciliary base and should be used for annotation whenever possible. Also, note that cilia and eukaryotic flagella are deemed to be equivalent.		pr	2013-12-17T14:16:04Z						cellular_component											owl:Class	
GO:0032415	biolink:NamedThing	regulation of sodium:proton antiporter activity	Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).	got7fsn_ti	regulation of sodium:hydrogen antiporter activity													biological_process											owl:Class	
GO:0014717	biolink:NamedThing	regulation of satellite cell activation involved in skeletal muscle regeneration	Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.	got7fsn_ti														biological_process											owl:Class	
GO:1905622	biolink:NamedThing	negative regulation of leaf development	Any process that stops, prevents or reduces the frequency, rate or extent of leaf development.	got7fsn_ti	down regulation of leaf development|down-regulation of leaf development|downregulation of leaf development|inhibition of leaf development						pga	2016-10-28T15:29:57Z						biological_process											owl:Class	
GO:0044317	biolink:NamedThing	rod spherule	A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body.	got7fsn_ti	rod photoreceptor spherule|rod cell spherule						jl	2010-07-14T01:38:07Z						cellular_component											owl:Class	
CL:0000604	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901212	biolink:NamedThing	positive regulation of cardiac chamber formation	Any process that activates or increases the frequency, rate or extent of cardiac chamber formation.	got7fsn_ti	up-regulation of cardiac chamber formation|upregulation of heart chamber formation|up-regulation of heart chamber formation|positive regulation of heart chamber formation|activation of cardiac chamber formation|activation of heart chamber formation|up regulation of heart chamber formation|upregulation of cardiac chamber formation|up regulation of cardiac chamber formation						rl	2012-07-31T07:19:05Z						biological_process											owl:Class	
GO:0000779	biolink:NamedThing	condensed chromosome, centromeric region	The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.	got7fsn_ti	condensed chromosome, pericentric region|condensed chromosome, centric region|condensed nuclear chromosome, centromeric region|condensed chromosome, centromere				Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex.						GO:0000780			cellular_component											owl:Class	
GO:0075527	biolink:NamedThing	viral RNA editing	The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon.	got7fsn_ti	RNA editing involved in viral mRNA transcription						jl	2011-08-04T02:07:03Z				VZ:857		biological_process											owl:Class	
GO:0000352	biolink:NamedThing	trans assembly of SL-containing precatalytic spliceosome	Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA.	got7fsn_ti	trans assembly of spliced leader-containing precatalytic spliceosome													biological_process											owl:Class	
GO:0098023	biolink:NamedThing	virus tail, tip	The basal end of the virus tail, which is used by the virus to attach to the host cell.	got7fsn_ti	bacteriophage tail tip						bm	2012-07-19T14:13:02Z						cellular_component											owl:Class	
GO:0030094	biolink:NamedThing	plasma membrane-derived photosystem I	A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species.	got7fsn_ti	plasma membrane photosystem I													cellular_component											owl:Class	
GO:0099086	biolink:NamedThing	synaptonemal structure	A proteinaceous scaffold found between homologous chromosomes during meiosis.	got7fsn_ti														cellular_component											owl:Class	
GO:0005275	biolink:NamedThing	amine transmembrane transporter activity	Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.	got7fsn_ti	amine/amide/polyamine channel activity|amine/polyamine transmembrane transporter activity|amino acid-polyamine transmembrane transporter activity										GO:0005279			molecular_function											owl:Class	
GO:0015837	biolink:NamedThing	amine transport	The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	amine/polyamine transport													biological_process											owl:Class	
GO:0099535	biolink:NamedThing	synapse-associated extracellular matrix	The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.	got7fsn_ti	extra-synaptic extracellular matrix													cellular_component											owl:Class	
GO:0039691	biolink:NamedThing	double stranded viral RNA replication	A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA.	got7fsn_ti							bf	2013-10-17T15:52:19Z				VZ:1936		biological_process											owl:Class	
GO:0043504	biolink:NamedThing	mitochondrial DNA repair	The process of restoring mitochondrial DNA after damage.	got7fsn_ti														biological_process											owl:Class	
GO:0001228	biolink:NamedThing	DNA-binding transcription activator activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.	got7fsn_ti	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding|RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, metal ion regulated sequence-specific DNA binding|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding|transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding|zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription|proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific|transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding|distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific	https://github.com/geneontology/go-ontology/issues/16534|https://github.com/geneontology/go-ontology/issues/16152|https://github.com/geneontology/go-ontology/issues/16131|https://github.com/geneontology/go-ontology/issues/20253			For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2012-01-26T03:10:20Z			GO:0001211|GO:0001213|GO:0001212|GO:0001077|GO:0001209|GO:0001205			molecular_function											owl:Class	
GO:0046787	biolink:NamedThing	viral DNA repair	The process of restoring viral DNA after damage or errors in replication.	got7fsn_ti														biological_process											owl:Class	
GO:0043311	biolink:NamedThing	positive regulation of eosinophil degranulation	Any process that activates or increases the frequency, rate or extent of eosinophil degranulation.	got7fsn_ti	positive regulation of eosinophil granule exocytosis|stimulation of eosinophil degranulation|up-regulation of eosinophil degranulation|up regulation of eosinophil degranulation|upregulation of eosinophil degranulation|activation of eosinophil degranulation													biological_process											owl:Class	
GO:0051973	biolink:NamedThing	positive regulation of telomerase activity	Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).	got7fsn_ti	activation of telomerase activity|upregulation of telomerase activity|stimulation of telomerase activity|telomerase activator|up regulation of telomerase activity|up-regulation of telomerase activity													biological_process											owl:Class	
GO:1901214	biolink:NamedThing	regulation of neuron death	Any process that modulates the frequency, rate or extent of neuron death.	got7fsn_ti	regulation of neuron cell death|regulation of neuronal cell death						rph	2012-08-02T09:57:41Z						biological_process											owl:Class	
GO:0140663	biolink:NamedThing	ATP-dependent FeS chaperone activity	Binding to and delivering metal ions to a target protein, driven by ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21661					pg	2021-06-19T16:33:09Z						molecular_function											owl:Class	
GO:0072258	biolink:NamedThing	metanephric interstitial fibroblast differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state.	got7fsn_ti	metanephros interstitial cell differentiation						mah	2010-03-19T04:17:32Z						biological_process											owl:Class	
GO:0043539	biolink:NamedThing	protein serine/threonine kinase activator activity	Binds to and increases the activity of a protein serine/threonine kinase.	got7fsn_ti	protein ser/thr kinase activator activity													molecular_function											owl:Class	
GO:0071902	biolink:NamedThing	positive regulation of protein serine/threonine kinase activity	Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.	got7fsn_ti							mah	2010-09-15T03:09:57Z						biological_process											owl:Class	
GO:0008377	biolink:NamedThing	light-induced release of internally sequestered calcium ion	The process in which the detection of light triggers the release of internally sequestered calcium ions.	got7fsn_ti	light-induced release of internally stored calcium ion (Ca2+)|light-induced release of calcium from internal store|light-induced release of internally sequestered calcium ion (Ca2+)													biological_process											owl:Class	
GO:0016056	biolink:NamedThing	rhodopsin mediated signaling pathway	The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.	got7fsn_ti	rhodopsin mediated phototransduction|rhodopsin mediated signalling pathway|rhodopsin signaling										GO:0009586			biological_process											owl:Class	
GO:0031360	biolink:NamedThing	intrinsic component of thylakoid membrane	The component of the thylakoid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to thylakoid membrane													cellular_component											owl:Class	
GO:1905617	biolink:NamedThing	negative regulation of miRNA mediated inhibition of translation	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA mediated inhibition of translation.	got7fsn_ti	down-regulation of negative regulation of translation involved in gene silencing by microRNA|down-regulation of miRNA mediated inhibition of translation|down regulation of negative regulation of translation involved in gene silencing by microRNA|down regulation of miRNA-mediated gene silencing, negative regulation of translation|inhibition of gene silencing by miRNA, negative regulation of translation|down-regulation of miRNA-mediated gene silencing, negative regulation of translation|down regulation of down-regulation of translation involved in gene silencing by miRNA|inhibition of inhibition of translation involved in gene silencing by miRNA|inhibition of negative regulation of translation involved in gene silencing by microRNA|negative regulation of down-regulation of translation involved in gene silencing by miRNA|inhibition of downregulation of translation involved in gene silencing by miRNA|inhibition of down-regulation of translation involved in gene silencing by miRNA|negative regulation of miRNA-mediated gene silencing, negative regulation of translation|downregulation of miRNA-mediated gene silencing, negative regulation of translation|down-regulation of gene silencing by miRNA, negative regulation of translation|inhibition of miRNA-mediated gene silencing, negative regulation of translation|negative regulation of inhibition of translation involved in gene silencing by miRNA|downregulation of down-regulation of translation involved in gene silencing by miRNA|down regulation of miRNA mediated inhibition of translation|downregulation of gene silencing by miRNA, negative regulation of translation|down regulation of down regulation of translation involved in gene silencing by miRNA|downregulation of negative regulation of translation involved in gene silencing by microRNA|inhibition of down regulation of translation involved in gene silencing by miRNA|down-regulation of down regulation of translation involved in gene silencing by miRNA|downregulation of inhibition of translation involved in gene silencing by miRNA|down-regulation of down-regulation of translation involved in gene silencing by miRNA|down regulation of downregulation of translation involved in gene silencing by miRNA|negative regulation of negative regulation of translation involved in gene silencing by microRNA|down-regulation of inhibition of translation involved in gene silencing by miRNA|downregulation of miRNA mediated inhibition of translation|negative regulation of downregulation of translation involved in gene silencing by miRNA|downregulation of downregulation of translation involved in gene silencing by miRNA|inhibition of miRNA mediated inhibition of translation|down regulation of inhibition of translation involved in gene silencing by miRNA|negative regulation of gene silencing by miRNA, negative regulation of translation|down-regulation of downregulation of translation involved in gene silencing by miRNA|negative regulation of down regulation of translation involved in gene silencing by miRNA|down regulation of gene silencing by miRNA, negative regulation of translation|downregulation of down regulation of translation involved in gene silencing by miRNA						bc	2016-10-28T11:47:57Z						biological_process											owl:Class	
GO:0005365	biolink:NamedThing	myo-inositol transmembrane transporter activity	Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.	got7fsn_ti	vitamin Bh transporter activity													molecular_function											owl:Class	
GO:0015798	biolink:NamedThing	myo-inositol transport	The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.	got7fsn_ti	vitamin Bh transport													biological_process											owl:Class	
GO:0003167	biolink:NamedThing	atrioventricular bundle cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.	got7fsn_ti	AV bundle cell differentiation						dph	2009-10-01T02:48:23Z						biological_process											owl:Class	
GO:0003166	biolink:NamedThing	bundle of His development	The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.	got7fsn_ti	atrioventricular bundle development						dph	2009-10-01T02:08:43Z						biological_process											owl:Class	
GO:2001190	biolink:NamedThing	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.	got7fsn_ti	positive regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|positive regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|positive regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell						yaf	2011-11-03T01:31:40Z						biological_process											owl:Class	
GO:0045506	biolink:NamedThing	interleukin-24 receptor activity	Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-24R|IL-24 receptor activity													molecular_function											owl:Class	
GO:0045510	biolink:NamedThing	interleukin-24 binding	Binding to interleukin-24.	got7fsn_ti	IL-24 binding													molecular_function											owl:Class	
GO:0004536	biolink:NamedThing	deoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.	got7fsn_ti	caspase-activated deoxyribonuclease activity										GO:0004537	Reactome:R-HSA-5685994|Reactome:R-HSA-211247|Reactome:R-HSA-6785986		molecular_function											owl:Class	
GO:1990222	biolink:NamedThing	ProVWX complex	The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma membrane and is activated under osmotic stress conditions.	got7fsn_ti	ATP-binding cassette (ABC) transporter complex ProVWX						bhm	2013-10-16T09:09:17Z						cellular_component											owl:Class	
GO:1904413	biolink:NamedThing	negative regulation of cardiac ventricle development	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development.	got7fsn_ti	downregulation of cardiac ventricle development|inhibition of cardiac ventricle development|down-regulation of cardiac ventricle development|down regulation of cardiac ventricle development						sl	2015-06-25T19:52:21Z						biological_process											owl:Class	
GO:0033335	biolink:NamedThing	anal fin development	The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0034992	biolink:NamedThing	microtubule organizing center attachment site	A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.	got7fsn_ti	MAS|microtubule organising centre attachment site|MTOC attachment site				Note that this term should not be confused with the cellular component term 'perinuclear region ; GO:0048471'.									cellular_component											owl:Class	
GO:0005228	biolink:NamedThing	intracellular sodium activated potassium channel activity	Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:29103	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902938	biolink:NamedThing	regulation of intracellular calcium activated chloride channel activity	Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity.	got7fsn_ti							als	2014-04-28T08:49:08Z						biological_process											owl:Class	
GO:0060338	biolink:NamedThing	regulation of type I interferon-mediated signaling pathway	Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.	got7fsn_ti	regulation of type I interferon-mediated signalling pathway													biological_process											owl:Class	
GO:0001650	biolink:NamedThing	fibrillar center	A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.	got7fsn_ti	fibrillar centre													cellular_component											owl:Class	
GO:0005836	biolink:NamedThing	fatty-acyl-CoA synthase complex	A protein complex that possesses fatty-acyl-CoA synthase activity.	got7fsn_ti	fatty acyl CoA synthase complex				Note that fatty acid synthetases of vertebrates and yeast are stable enzyme complexes of multifunctional polypeptide chains, whereas the fatty acid synthetases of plants and E. coli consist of non-associated individual enzymes.									cellular_component											owl:Class	
GO:0019801	biolink:NamedThing	cyclization of asparagine involved in intein-mediated protein splicing	The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.	got7fsn_ti	cyclization of asparagine, during protein splicing				See also the biological process term 'intein-mediated protein splicing ; GO:0016539'.							RESID:AA0302		biological_process											owl:Class	
GO:0016539	biolink:NamedThing	intein-mediated protein splicing	The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.	got7fsn_ti	intein													biological_process											owl:Class	
GO:0046964	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other.	got7fsn_ti	3'-phosphoadenosine 5'-phosphosulphate transporter activity|PAPS transporter activity|adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity											Reactome:R-HSA-741449		molecular_function											owl:Class	
GO:1902559	biolink:NamedThing	3'-phospho-5'-adenylyl sulfate transmembrane transport	The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane.	got7fsn_ti	3'-phosphoadenosine 5'-phosphosulfate transmembrane transport						mcc	2013-12-09T23:19:04Z						biological_process											owl:Class	
GO:0030915	biolink:NamedThing	Smc5-Smc6 complex	A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.	got7fsn_ti														cellular_component											owl:Class	
GO:0000793	biolink:NamedThing	condensed chromosome	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.	got7fsn_ti	cytoplasmic mitotic chromosome|metaphase chromosome|mitotic chromosome				Note that this term can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes an 'open mitosis' in which the nuclear envelope breaks down during mitosis.									cellular_component											owl:Class	
GO:0005672	biolink:NamedThing	transcription factor TFIIA complex	A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12).	got7fsn_ti														cellular_component											owl:Class	
GO:1990731	biolink:NamedThing	UV-damage excision repair, DNA incision	A process that results in the endonucleolytic cleavage of the damaged strand of DNA immediately 5' of a UV-induced damage site, and is the first part of a DNA repair process that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).	got7fsn_ti	UV-damaged DNA endonuclease-dependent excision repair, DNA incision|DNA incision involved in UVER|nucleic acid cleavage involved in UV-damage excision repair|UVDE-dependent excision repair, DNA incision|DNA incision involved in alternative excision repair|DNA incision involved in UV-damaged DNA endonuclease-dependent excision repair|DNA incision involved in UV-damage excision repair|DNA incision involved in UVDE-dependent excision repair|DNA incision involved in AER|alternative excision repair, DNA incision						mah	2015-04-21T15:09:04Z						biological_process											owl:Class	
GO:0110028	biolink:NamedThing	positive regulation of mitotic spindle organization	Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.	got7fsn_ti							kmv	2017-07-06T14:14:08Z						biological_process											owl:Class	
GO:0000080	biolink:NamedThing	mitotic G1 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.	got7fsn_ti	G1 phase of mitotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0097197	biolink:NamedThing	tetraspanin-enriched microdomain	A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.	got7fsn_ti	TEM|membrane tetraspanin-enriched microdomain						pr	2011-12-02T04:21:37Z						cellular_component											owl:Class	
GO:0030988	biolink:NamedThing	high molecular weight kininogen receptor complex	A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0000964	biolink:NamedThing	mitochondrial RNA 5'-end processing	Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.	got7fsn_ti	mitochondrial RNA 5' end processing													biological_process											owl:Class	
GO:0033614	biolink:NamedThing	chloroplast proton-transporting ATP synthase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0007358	biolink:NamedThing	establishment of central gap gene boundaries	Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel.	got7fsn_ti														biological_process											owl:Class	
GO:0097105	biolink:NamedThing	presynaptic membrane assembly	The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a  specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.	got7fsn_ti	pre-synaptic membrane assembly				Note that 'presynaptic membrane' in this term should not be mistaken with 'presynaptic active zone'. The latter encompasses more than the former, as it also includes the specialized cortical cytoskeletal matrix in the cell cortex of a presynaptic neuron.		pr	2011-07-27T01:30:45Z						biological_process											owl:Class	
GO:0001549	biolink:NamedThing	cumulus cell differentiation	The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell.	got7fsn_ti	ovarian cumulus cell differentiation													biological_process											owl:Class	
GO:0019960	biolink:NamedThing	C-X3-C chemokine binding	Binding to a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.	got7fsn_ti														molecular_function											owl:Class	
GO:0048093	biolink:NamedThing	positive regulation of male pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males.	got7fsn_ti	upregulation of male pigmentation|activation of male pigmentation|up-regulation of male pigmentation|up regulation of male pigmentation|stimulation of male pigmentation													biological_process											owl:Class	
GO:0099546	biolink:NamedThing	protein catabolic process, modulating synaptic transmission	Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0080161	biolink:NamedThing	auxin transmembrane transporter activity	Enables the transfer of auxins from one side of a membrane to the other. Auxins are plant hormones that regulate aspects of plant growth.	got7fsn_ti							dhl	2010-09-23T03:37:43Z						molecular_function											owl:Class	
GO:0031080	biolink:NamedThing	nuclear pore outer ring	A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates).	got7fsn_ti	Nup84 complex|Nup107-160 complex|Nup107-120 complex													cellular_component											owl:Class	
GO:0140442	biolink:NamedThing	peroxide sensor activity	Binding to hydrogen peroxide (H2O2) and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19126					pg	2020-03-24T09:09:43Z						molecular_function											owl:Class	
CHEBI:14321	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0106160	biolink:NamedThing	negative regulation of small RNA loading onto RISC	Any process that stops, prevents or reduces the frequency, rate or extent of small RNA loading onto RISC.	got7fsn_ti							hjd	2018-11-30T15:42:16Z						biological_process											owl:Class	
GO:0086059	biolink:NamedThing	voltage-gated calcium channel activity involved SA node cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated calcium channel activity involved in SA node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in sinus node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in SAN cardiac muscle cell action potential|voltage-gated calcium channel activity involved in sinoatrial node cardiac muscle cell action potential						dph	2011-11-17T12:39:27Z						molecular_function											owl:Class	
GO:0062075	biolink:NamedThing	pollen aperture formation	The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall.	got7fsn_ti							dph	2018-09-19T19:25:59Z						biological_process											owl:Class	
GO:0019164	biolink:NamedThing	pyruvate synthase activity	Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.	got7fsn_ti	PFOR|pyruvate:ferredoxin oxidoreductase activity|pyruvate-ferredoxin reductase activity|pyruvate oxidoreductase activity|pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)|pyruvate synthetase activity|pyruvic-ferredoxin oxidoreductase activity										GO:0018696	RHEA:12765|MetaCyc:PYRUFLAVREDUCT-RXN|EC:1.2.7.1|KEGG_REACTION:R01196		molecular_function											owl:Class	
GO:0006086	biolink:NamedThing	acetyl-CoA biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.	got7fsn_ti	acetyl-CoA synthesis from pyruvate|acetyl-CoA anabolism from pyruvate|pyruvate dehydrogenase pathway|acetyl-CoA formation from pyruvate											MetaCyc:PYRUVDEHYD-PWY		biological_process											owl:Class	
GO:0004170	biolink:NamedThing	dUTP diphosphatase activity	Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate.	got7fsn_ti	desoxyuridine 5'-triphosphate nucleotidohydrolase activity|dUTP nucleotidohydrolase activity|deoxyuridine-triphosphatase activity|desoxyuridine 5'-triphosphatase activity|dUTPase activity|dUTP pyrophosphatase activity											MetaCyc:DUTP-PYROP-RXN|RHEA:10248|EC:3.6.1.23|KEGG_REACTION:R02100|Reactome:R-HSA-73666		molecular_function											owl:Class	
GO:0015129	biolink:NamedThing	lactate transmembrane transporter activity	Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.	got7fsn_ti	monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity											Reactome:R-HSA-373875|Reactome:R-HSA-373867		molecular_function											owl:Class	
GO:0035873	biolink:NamedThing	lactate transmembrane transport	The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.	got7fsn_ti	lactate membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2011-05-31T09:26:59Z						biological_process											owl:Class	
GO:2001271	biolink:NamedThing	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.	got7fsn_ti	negative regulation of effector caspase activity						pr	2011-12-13T07:59:42Z						biological_process											owl:Class	
GO:0070132	biolink:NamedThing	regulation of mitochondrial translational initiation	Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.	got7fsn_ti	regulation of mitochondrial translation initiation													biological_process											owl:Class	
GO:0051387	biolink:NamedThing	negative regulation of neurotrophin TRK receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.	got7fsn_ti	down-regulation of nerve growth factor receptor signaling pathway|down regulation of nerve growth factor receptor signaling pathway|inhibition of nerve growth factor receptor signaling pathway|negative regulation of NGF receptor signaling pathway|negative regulation of nerve growth factor receptor signaling pathway|negative regulation of NGF receptor signalling pathway|negative regulation of nerve growth factor receptor signalling pathway|downregulation of nerve growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0072272	biolink:NamedThing	proximal/distal pattern formation involved in metanephric nephron development	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).	got7fsn_ti	proximal/distal metanephric nephron patterning|proximal-distal pattern formation involved in metanephric nephron development						mah	2010-03-30T03:25:37Z						biological_process											owl:Class	
GO:2000621	biolink:NamedThing	regulation of DNA replication termination	Any process that modulates the frequency, rate or extent of DNA replication termination.	got7fsn_ti							pr	2011-04-18T03:26:23Z						biological_process											owl:Class	
GO:1990900	biolink:NamedThing	ciliary pocket collar	A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma.	got7fsn_ti	FPC|flagellar collar|cilium pocket collar|flagellum pocket collar|flagellar pore|flagellar pocket collar				Note that a 'flagellar collar' is described in Choanoflagellates, but this is different from the ciliary pocket collar found e.g. in Giardia; in Choanoflagellates, a single apical flagellum is surrounded by a collar of 30-40 microvilli.		pr	2015-11-17T14:43:55Z						cellular_component											owl:Class	
GO:1905139	biolink:NamedThing	apical ectodermal ridge formation	The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti	AER formation|apical epidermal ridge formation|crista ectodermalis apicalis formation						dph	2016-04-13T11:46:40Z						biological_process											owl:Class	
GO:0042890	biolink:NamedThing	3-phenylpropionic acid transmembrane transporter activity	Enables the transfer of 3-phenylpropionic acid from one side of a membrane to the other.	got7fsn_ti	hydrocinnamic acid transporter activity|3-phenylpropionate acid transporter activity|HCA transporter activity													molecular_function											owl:Class	
GO:0042889	biolink:NamedThing	3-phenylpropionic acid transport	The directed movement of 3-phenylpropionic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	3-phenylpropionate transport|hydrocinnamic acid transport|HCA transport													biological_process											owl:Class	
GO:0017089	biolink:NamedThing	glycolipid transfer activity	Removes a glycolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. A glycolipid is a compound usually containing 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid.	got7fsn_ti	intermembrane glycolipid transfer activity|glycolipid carrier activity|intermembrane glycolipid transporter activity|glycolipid transporter activity											Reactome:R-HSA-9697077|Reactome:R-HSA-5340320		molecular_function											owl:Class	
GO:0046836	biolink:NamedThing	glycolipid transport	The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0098895	biolink:NamedThing	postsynaptic endosome membrane	The lipid bilayer surrounding a postsynaptic endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0098845	biolink:NamedThing	postsynaptic endosome	An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse.	got7fsn_ti														cellular_component											owl:Class	
GO:0042412	biolink:NamedThing	taurine biosynthetic process	The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.	got7fsn_ti	taurine formation|taurine anabolism|taurine biosynthesis|taurine synthesis													biological_process											owl:Class	
GO:0015499	biolink:NamedThing	formate transmembrane transporter activity	Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.	got7fsn_ti	formate uptake permease activity|formate uptake transmembrane transporter activity										GO:0015659	RHEA:29679		molecular_function											owl:Class	
GO:0015724	biolink:NamedThing	formate transport	The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0046626	biolink:NamedThing	regulation of insulin receptor signaling pathway	Any process that modulates the frequency, rate or extent of insulin receptor signaling.	got7fsn_ti	regulation of insulin receptor signalling pathway													biological_process											owl:Class	
GO:0010457	biolink:NamedThing	centriole-centriole cohesion	The cell cycle process in which the two centrioles within a centrosome remain tightly paired.	got7fsn_ti														biological_process											owl:Class	
GO:0045630	biolink:NamedThing	positive regulation of T-helper 2 cell differentiation	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.	got7fsn_ti	activation of T-helper 2 cell differentiation|stimulation of T-helper 2 cell differentiation|up-regulation of T-helper 2 cell differentiation|upregulation of T-helper 2 cell differentiation|up regulation of T-helper 2 cell differentiation|positive regulation of T-helper 2 cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0072540	biolink:NamedThing	T-helper 17 cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.	got7fsn_ti	Th17 fate commitment|Th17 cell lineage commitment|T-helper 17 cell fate commitment						mah	2011-01-17T11:19:48Z						biological_process											owl:Class	
GO:0035193	biolink:NamedThing	larval central nervous system remodeling	Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	CNS metamorphosis|central nervous system metamorphosis													biological_process											owl:Class	
GO:0042047	biolink:NamedThing	W-molybdopterin cofactor biosynthetic process	The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.	got7fsn_ti	W-molybdopterin cofactor biosynthesis|W-molybdopterin cofactor synthesis|W-molybdopterin cofactor formation|Moco biosynthesis|Moco biosynthetic process|W-molybdopterin cofactor anabolism													biological_process											owl:Class	
GO:1902917	biolink:NamedThing	positive regulation of mating projection assembly	Any process that activates or increases the frequency, rate or extent of mating projection assembly.	got7fsn_ti	positive regulation of mating projection biogenesis|upregulation of mating projection biogenesis|up regulation of mating projection biogenesis|activation of mating projection assembly|up regulation of mating projection assembly|upregulation of mating projection assembly|up-regulation of mating projection assembly|up-regulation of mating projection biogenesis|activation of mating projection biogenesis						di	2014-04-20T11:18:03Z						biological_process											owl:Class	
GO:0031139	biolink:NamedThing	positive regulation of conjugation with cellular fusion	Any process that increases the rate or frequency of conjugation with cellular fusion.	got7fsn_ti	up-regulation of conjugation with cellular fusion|stimulation of conjugation with cellular fusion|up regulation of conjugation with cellular fusion|upregulation of conjugation with cellular fusion|activation of conjugation with cellular fusion													biological_process											owl:Class	
OBO:OPL_0000114	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060212	biolink:NamedThing	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening	Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.	got7fsn_ti	negative regulation of 3' to 5' mRNA deadenylation|negative regulation of mRNA deadenylation|negative regulation of nuclear mRNA poly(A) tail shortening													biological_process											owl:Class	
GO:0002798	biolink:NamedThing	negative regulation of antibacterial peptide secretion	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion.	got7fsn_ti	inhibition of antibacterial peptide secretion|down-regulation of antibacterial peptide secretion|downregulation of antibacterial peptide secretion|down regulation of antibacterial peptide secretion													biological_process											owl:Class	
GO:1903060	biolink:NamedThing	negative regulation of protein lipidation	Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation.	got7fsn_ti	down-regulation of protein lipidation|inhibition of protein lipidation|negative regulation of protein amino acid lipidation|downregulation of protein lipidation|down-regulation of protein amino acid lipidation|downregulation of protein amino acid lipidation|downregulation of lipid:protein modification|inhibition of lipid:protein modification|down regulation of lipid:protein modification|down regulation of protein lipidation|down-regulation of lipid:protein modification|inhibition of protein amino acid lipidation|negative regulation of lipid:protein modification|down regulation of protein amino acid lipidation						rph	2014-05-28T13:21:25Z						biological_process											owl:Class	
GO:0021620	biolink:NamedThing	hypoglossal nerve formation	The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	got7fsn_ti	CN XII biosynthesis|CN XII formation													biological_process											owl:Class	
GO:0106055	biolink:NamedThing	mannosyl-oligosaccharide 1,2-alpha-mannosidase complex	A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.	got7fsn_ti					An example is MNL1 (P38888) in Saccharomyces cerevisiae. PMID:19124653 (by physical interaction evidence).		hjd	2017-09-14T15:23:28Z						cellular_component											owl:Class	
GO:0021523	biolink:NamedThing	somatic motor neuron differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0048053	biolink:NamedThing	R1/R6 development	The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0090637	biolink:NamedThing	inner dense plaque of desmosome	The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane.	got7fsn_ti							tb	2015-04-20T16:10:51Z						cellular_component											owl:Class	
GO:0007499	biolink:NamedThing	ectoderm and mesoderm interaction	A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm.	got7fsn_ti	ectoderm/mesoderm interaction													biological_process											owl:Class	
UBERON:0003053	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005324	biolink:NamedThing	long-chain fatty acid transporter activity	Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti											GO:0005325|GO:0008562	Reactome:R-HSA-5684043|Reactome:R-HSA-434381|Reactome:R-HSA-2046087|Reactome:R-HSA-382575|Reactome:R-HSA-390393|Reactome:R-HSA-2046093		molecular_function											owl:Class	
GO:0035859	biolink:NamedThing	Seh1-associated complex	A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p.	got7fsn_ti	SEA complex|GATOR complex	https://github.com/geneontology/go-ontology/issues/21778			The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ;  GO:1990131.		bf	2011-05-17T10:59:50Z						cellular_component											owl:Class	
GO:1903294	biolink:NamedThing	regulation of glutamate secretion, neurotransmission	Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission.	got7fsn_ti					An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype		pad	2014-08-13T13:54:15Z						biological_process											owl:Class	
GO:0042009	biolink:NamedThing	interleukin-15 binding	Binding to interleukin-15.	got7fsn_ti	IL-15 binding													molecular_function											owl:Class	
GO:0097231	biolink:NamedThing	cell motility in response to calcium ion	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.	got7fsn_ti	calcium ion facilitation of cell motility|Ca2+ facilitation of cell motility						pr	2012-01-25T04:42:45Z						biological_process											owl:Class	
GO:1904113	biolink:NamedThing	negative regulation of muscle filament sliding	Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding.	got7fsn_ti	down regulation of muscle filament sliding|inhibition of muscle filament sliding|downregulation of muscle filament sliding|down-regulation of muscle filament sliding						kmv	2015-04-03T18:40:38Z						biological_process											owl:Class	
GO:0033600	biolink:NamedThing	negative regulation of mammary gland epithelial cell proliferation	Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.	got7fsn_ti	down-regulation of mammary gland epithelial cell proliferation|inhibition of mammary gland epithelial cell proliferation|downregulation of mammary gland epithelial cell proliferation|down regulation of mammary gland epithelial cell proliferation													biological_process											owl:Class	
GO:1901193	biolink:NamedThing	regulation of formation of translation preinitiation complex	Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex.	got7fsn_ti	regulation of translation preinitiation complex assembly|regulation of formation of translation pre-initiation complex						ss	2012-07-25T02:31:20Z						biological_process											owl:Class	
GO:0090417	biolink:NamedThing	N-methylnicotinate transmembrane transporter activity	Enables the transfer of N-methylnicotinate from one side of a membrane to the other.	got7fsn_ti	N-methylnicotinate transporter activity						tb	2011-10-19T11:09:59Z						molecular_function											owl:Class	
GO:2001143	biolink:NamedThing	N-methylnicotinate transport	The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2011-10-18T05:16:08Z						biological_process											owl:Class	
GO:0008363	biolink:NamedThing	larval chitin-based cuticle development	Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.	got7fsn_ti	larval cuticle anabolism|larval cuticle synthesis|larval cuticle biosynthetic process|larval cuticle formation													biological_process											owl:Class	
GO:1990589	biolink:NamedThing	ATF4-CREB1 transcription factor complex	Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway.	got7fsn_ti							bhm	2014-12-15T14:22:44Z						cellular_component											owl:Class	
GO:1903762	biolink:NamedThing	positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.	got7fsn_ti	up regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|positive regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|activation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|up regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|up-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|activation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|upregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|up-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential						rl	2014-12-19T12:02:18Z						biological_process											owl:Class	
GO:0032074	biolink:NamedThing	negative regulation of nuclease activity	Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.	got7fsn_ti	down-regulation of nuclease activity|downregulation of nuclease activity|inhibition of nuclease activity|down regulation of nuclease activity|nuclease inhibitor													biological_process											owl:Class	
GO:1990207	biolink:NamedThing	EmrE multidrug transporter complex	A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer.	got7fsn_ti	EmrE complex						bhm	2013-10-08T08:37:52Z						cellular_component											owl:Class	
GO:0044718	biolink:NamedThing	siderophore transmembrane transport	The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore.	got7fsn_ti	siderophore membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		jl	2012-10-18T13:43:56Z						biological_process											owl:Class	
GO:1903689	biolink:NamedThing	regulation of wound healing, spreading of epidermal cells	Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells.	got7fsn_ti							als	2014-12-01T15:54:18Z						biological_process											owl:Class	
GO:0061147	biolink:NamedThing	endocardial endothelium development	The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	got7fsn_ti							dph	2010-06-03T09:15:31Z						biological_process											owl:Class	
GO:0003290	biolink:NamedThing	atrial septum secundum morphogenesis	The process in which anatomical structure of an atrial septum secundum is generated and organized.	got7fsn_ti							dph	2009-10-20T10:33:57Z						biological_process											owl:Class	
GO:0033362	biolink:NamedThing	lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps.	got7fsn_ti	lysine synthesis via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine anabolism via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine biosynthesis via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine formation via diaminopimelate, diaminopimelate-aminotransferase pathway											MetaCyc:PWY-5097		biological_process											owl:Class	
GO:0004704	biolink:NamedThing	NF-kappaB-inducing kinase activity	Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK).	got7fsn_ti	NIK													molecular_function											owl:Class	
GO:0061452	biolink:NamedThing	retrotrapezoid nucleus neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.	got7fsn_ti							dph	2012-07-19T12:43:18Z						biological_process											owl:Class	
GO:2000731	biolink:NamedThing	negative regulation of termination of RNA polymerase I transcription	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription.	got7fsn_ti	negative regulation of transcription termination from RNA polymerase I promoter|negative regulation of transcription termination from Pol I promoter|negative regulation of RNA polymerase I transcription termination						dph	2011-06-10T08:43:44Z						biological_process											owl:Class	
GO:0072004	biolink:NamedThing	kidney field specification	The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop.	got7fsn_ti	specification of kidney anlage						mah	2010-01-25T11:24:33Z						biological_process											owl:Class	
GO:0051486	biolink:NamedThing	isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.	got7fsn_ti	isopentenyl diphosphate formation, mevalonate pathway, during terpenoid biosynthesis|isopentenyl diphosphate synthesis, mevalonate pathway, during terpenoid synthesis|isopentenyl diphosphate biosynthetic process, mevalonate pathway, during terpenoid biosynthetic process|isopentenyl diphosphate anabolism, mevalonate pathway, during terpenoid anabolism|isopentenyl diphosphate formation, mevalonate pathway, during terpenoid formation													biological_process											owl:Class	
GO:0051485	biolink:NamedThing	terpenoid biosynthetic process, mevalonate-dependent	The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.	got7fsn_ti	terpenoid synthesis, mevalonate-dependent|terpene biosynthetic process, mevalonate-dependent|terpenoid formation, mevalonate-dependent|terpene biosynthesis, mevalonate-dependent|terpenoid anabolism, mevalonate-dependent													biological_process											owl:Class	
GO:0060289	biolink:NamedThing	compartment boundary maintenance	A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.	got7fsn_ti														biological_process											owl:Class	
GO:0060574	biolink:NamedThing	intestinal epithelial cell maturation	The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.	got7fsn_ti							dph	2009-05-06T08:10:41Z						biological_process											owl:Class	
GO:0042800	biolink:NamedThing	histone methyltransferase activity (H3-K4 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein.	got7fsn_ti	histone lysine N-methyltransferase activity (H3-K4 specific)|histone H3 lysine 4-specific methyltransferase activity|histone methylase activity (H3-K4 specific)				Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H3 protein, but that this term still applies.							Reactome:R-HSA-8936621|Reactome:R-HSA-8937050|Reactome:R-HSA-8936481|Reactome:R-HSA-1214188|Reactome:R-HSA-8937016|Reactome:R-HSA-8865498|Reactome:R-HSA-3364026		molecular_function											owl:Class	
GO:0075017	biolink:NamedThing	regulation of appressorium formation	Any process that modulates the frequency, rate or extent of symbiont appressorium formation.	got7fsn_ti	regulation of appressorium formation on or near host													biological_process											owl:Class	
GO:0036156	biolink:NamedThing	inner dynein arm	Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.	got7fsn_ti	inner dynein arm complex						bf	2012-03-21T01:24:54Z						cellular_component											owl:Class	
GO:1902756	biolink:NamedThing	sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process	The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-).	got7fsn_ti	sulfurated eukaryotic molybdenum cofactor(2-) anabolism|sulfurated eukaryotic molybdenum cofactor(2-) biosynthesis|sulfurated eukaryotic molybdenum cofactor(2-) formation|sulfurated eukaryotic molybdenum cofactor(2-) synthesis						dph	2014-03-05T23:29:20Z				MetaCyc:PWY-6476|Reactome:R-HSA-947581		biological_process											owl:Class	
GO:0120321	biolink:NamedThing	nuclear envelope adjacent to nuclear pore complex	The region of the nuclear envelope situated in close proximity to a nuclear pore complex.	got7fsn_ti	associated with the nuclear pore|nuclear envelope periphery of the nuclear pore complex|nuclear envelope adjacent to NPC	https://github.com/geneontology/go-ontology/issues/21774					krc	2021-07-07T20:30:21Z						cellular_component											owl:Class	
GO:0034551	biolink:NamedThing	mitochondrial respiratory chain complex III assembly	The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane.	got7fsn_ti	mitochondrial cytochrome bc(1) complex assembly													biological_process											owl:Class	
GO:0022849	biolink:NamedThing	glutamate-gated calcium ion channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:29108	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014019	biolink:NamedThing	neuroblast development	The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.	got7fsn_ti														biological_process											owl:Class	
GO:0009539	biolink:NamedThing	photosystem II reaction center	An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone.	got7fsn_ti	photosystem II reaction centre													cellular_component											owl:Class	
GO:0031500	biolink:NamedThing	Tea1 cell-end complex	A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.	got7fsn_ti														cellular_component											owl:Class	
GO:0150201	biolink:NamedThing	positive regulation of transport across blood-brain barrier	Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier.	got7fsn_ti							bc	2020-03-26T19:26:38Z						biological_process											owl:Class	
GO:1905305	biolink:NamedThing	negative regulation of cardiac myofibril assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly.	got7fsn_ti	inhibition of cardiac myofibril development|down-regulation of cardiac myofibril assembly|negative regulation of cardiac myofibril development|downregulation of heart myofibril assembly|down-regulation of cardiac myofibril development|downregulation of cardiac myofibril morphogenesis|down regulation of heart myofibril assembly|down regulation of cardiac myofibril morphogenesis|negative regulation of cardiac myofibril morphogenesis|inhibition of cardiac myofibril assembly|down-regulation of cardiac myofibril morphogenesis|downregulation of cardiac myofibril assembly|down regulation of cardiac myofibril assembly|down regulation of cardiac myofibril development|inhibition of cardiac myofibril morphogenesis|downregulation of cardiac myofibril development|inhibition of heart myofibril assembly|down-regulation of heart myofibril assembly|negative regulation of heart myofibril assembly						rl	2016-07-06T10:01:58Z						biological_process											owl:Class	
GO:0038027	biolink:NamedThing	apolipoprotein A-I-mediated signaling pathway	A series of molecular signals initiated by the binding of apolipoprotein A-I to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	apolipoprotein A-I-mediated signalling pathway						bf	2011-08-02T02:13:41Z						biological_process											owl:Class	
GO:0090708	biolink:NamedThing	specification of plant organ axis polarity	The process in which the polarity of a plant organ axis is specified.	got7fsn_ti							tb	2016-10-05T12:47:11Z						biological_process											owl:Class	
GO:1903436	biolink:NamedThing	regulation of mitotic cytokinetic process	Any process that modulates the frequency, rate or extent of mitotic cytokinetic process.	got7fsn_ti							tb	2014-09-15T23:11:38Z						biological_process											owl:Class	
PO:0009062	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072180	biolink:NamedThing	mesonephric duct morphogenesis	The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.	got7fsn_ti	Wolffian duct morphogenesis						mah	2010-02-26T02:37:13Z						biological_process											owl:Class	
GO:0075306	biolink:NamedThing	regulation of conidium formation	Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	got7fsn_ti														biological_process											owl:Class	
GO:0098745	biolink:NamedThing	Dcp1-Dcp2 complex	A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA.	got7fsn_ti					Additional components may be present, for example in ascomycetes this complex includes an additional regulatory subunit, Edc1.									cellular_component											owl:Class	
GO:0072560	biolink:NamedThing	type B pancreatic cell maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.	got7fsn_ti	pancreatic beta cell maturation|pancreatic B cell maturation				These processes continue to 60 DPA in Gossypium spp.		mah	2011-01-27T01:57:14Z						biological_process											owl:Class	
GO:0021647	biolink:NamedThing	vestibulocochlear nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	got7fsn_ti	CN VIII maturation|auditory nerve maturation													biological_process											owl:Class	
GO:0010840	biolink:NamedThing	regulation of circadian sleep/wake cycle, wakefulness	Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.	got7fsn_ti														biological_process											owl:Class	
GO:1903178	biolink:NamedThing	positive regulation of tyrosine 3-monooxygenase activity	Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity.	got7fsn_ti	activation of tyrosine hydroxylase activity|up-regulation of tyrosine 3-monooxygenase activity|upregulation of L-tyrosine hydroxylase activity|up regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up regulation of L-tyrosine hydroxylase activity|upregulation of tyrosine 3-hydroxylase activity|stimulation of TH activity|activation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up-regulation of tyrosine 3-hydroxylase activity|positive regulation of tyrosine 3-hydroxylase activity|upregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up-regulation of tyrosine hydroxylase activity|upregulation of tyrosine hydroxylase activity|up regulation of tyrosine 3-monooxygenase activity|positive regulation of tyrosine hydroxylase activity|positive regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|activation of L-tyrosine hydroxylase activity|up-regulation of L-tyrosine hydroxylase activity|positive regulation of L-tyrosine hydroxylase activity|activation of tyrosine 3-monooxygenase activity|up-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up regulation of tyrosine 3-hydroxylase activity|up regulation of tyrosine hydroxylase activity|upregulation of tyrosine 3-monooxygenase activity|positive regulation of TH activity|activation of tyrosine 3-hydroxylase activity						bf	2014-07-14T10:39:21Z						biological_process											owl:Class	
GO:0002787	biolink:NamedThing	negative regulation of antibacterial peptide production	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.	got7fsn_ti	down-regulation of antibacterial peptide production|down regulation of antibacterial peptide production|inhibition of antibacterial peptide production|downregulation of antibacterial peptide production													biological_process											owl:Class	
GO:0071341	biolink:NamedThing	medial cortical node	A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.	got7fsn_ti	midsome|mid1p medial cortical dot						mah	2009-12-11T11:40:36Z						cellular_component											owl:Class	
GO:0001227	biolink:NamedThing	DNA-binding transcription repressor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.	got7fsn_ti	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding|metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific|RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding|transcriptional repressor activity, metal ion regulated sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription|proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific	https://github.com/geneontology/go-ontology/issues/16534|https://github.com/geneontology/go-ontology/issues/16152|https://github.com/geneontology/go-ontology/issues/16131|https://github.com/geneontology/go-ontology/issues/20253			For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2010-10-26T03:56:48Z			GO:0001206|GO:0001210|GO:0001078|GO:0001214			molecular_function											owl:Class	
GO:0035732	biolink:NamedThing	nitric oxide storage	The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.	got7fsn_ti	NO storage						bf	2011-03-11T10:00:31Z						biological_process											owl:Class	
GO:0061233	biolink:NamedThing	mesonephric glomerular basement membrane development	The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.	got7fsn_ti							dph	2010-08-19T02:52:18Z						biological_process											owl:Class	
GO:0050922	biolink:NamedThing	negative regulation of chemotaxis	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.	got7fsn_ti	down-regulation of chemotaxis|inhibition of chemotaxis|downregulation of chemotaxis|down regulation of chemotaxis													biological_process											owl:Class	
GO:0007086	biolink:NamedThing	vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly	The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly.	got7fsn_ti														biological_process											owl:Class	
GO:0097751	biolink:NamedThing	spore-bearing structure formation	The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores.	got7fsn_ti	sporangium formation|sporophore formation						pr	2017-01-11T13:55:24Z						biological_process											owl:Class	
GO:0070149	biolink:NamedThing	mitochondrial glutamyl-tRNA aminoacylation	The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0043294	biolink:NamedThing	mitochondrial glutamate synthase complex (NADH)	A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0030257	biolink:NamedThing	type III protein secretion system complex	A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase.	got7fsn_ti	TTSS complex|T3SS complex													cellular_component											owl:Class	
GO:0035157	biolink:NamedThing	negative regulation of fusion cell fate specification	Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.	got7fsn_ti	inhibition of fusion cell fate specification|downregulation of fusion cell fate specification|down-regulation of fusion cell fate specification|down regulation of fusion cell fate specification													biological_process											owl:Class	
GO:1903108	biolink:NamedThing	regulation of mitochondrial transcription	Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.	got7fsn_ti	regulation of mitochondrial transcription|regulation of transcription from mitochondrial promoter						al	2014-06-09T11:53:14Z						biological_process											owl:Class	
PO:0000084	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004383	biolink:NamedThing	guanylate cyclase activity	Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.	got7fsn_ti	guanylyl cyclase activity|receptor guanylate cyclase activity|GTP diphosphate-lyase (cyclizing) activity|GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity|guanyl cyclase activity											Reactome:R-HSA-392152|RHEA:13665|Reactome:R-HSA-74885|MetaCyc:GUANYLCYC-RXN|EC:4.6.1.2		molecular_function											owl:Class	
GO:0061687	biolink:NamedThing	detoxification of inorganic compound	Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.	got7fsn_ti							dph	2015-03-09T09:16:23Z						biological_process											owl:Class	
GO:0048041	biolink:NamedThing	focal adhesion assembly	The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.	got7fsn_ti	focal adhesion formation|adhesion plaque assembly													biological_process											owl:Class	
GO:0009424	biolink:NamedThing	bacterial-type flagellum hook	The portion of the bacterial-type flagellum that connects the filament to the basal body.	got7fsn_ti	flagellar hook|flagellin-based flagellum hook													cellular_component											owl:Class	
GO:0048394	biolink:NamedThing	intermediate mesodermal cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti	intermediate mesoderm cell fate determination													biological_process											owl:Class	
GO:0015889	biolink:NamedThing	cobalamin transport	The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	vitamin B12 transport													biological_process											owl:Class	
GO:0099175	biolink:NamedThing	regulation of postsynapse organization	Any process that modulates the physical form of a postsynapse.	got7fsn_ti	regulation of postsynapse organization and biogenesis|regulation of postsynapse organisation|regulation of postsynapse structure													biological_process											owl:Class	
GO:0070125	biolink:NamedThing	mitochondrial translational elongation	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.	got7fsn_ti	mitochondrial translation elongation													biological_process											owl:Class	
GO:1903933	biolink:NamedThing	negative regulation of DNA primase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity.	got7fsn_ti	down-regulation of DNA primase activity|down regulation of DNA primase activity|inhibition of DNA primase activity|downregulation of DNA primase activity						mah	2015-02-12T14:28:36Z						biological_process											owl:Class	
GO:0021663	biolink:NamedThing	rhombomere 4 formation	The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0071698	biolink:NamedThing	olfactory placode development	The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.	got7fsn_ti							mah	2010-03-02T12:45:14Z						biological_process											owl:Class	
GO:0040037	biolink:NamedThing	negative regulation of fibroblast growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.	got7fsn_ti	inhibition of fibroblast growth factor receptor signaling pathway|negative regulation of FGF receptor signalling pathway|negative regulation of FGF receptor signaling pathway|down-regulation of fibroblast growth factor receptor signaling pathway|negative regulation of FGFR signaling pathway|down regulation of fibroblast growth factor receptor signaling pathway|downregulation of fibroblast growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0048084	biolink:NamedThing	positive regulation of adult chitin-containing cuticle pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.	got7fsn_ti	up regulation of adult chitin-containing cuticle pigmentation|activation of adult chitin-containing cuticle pigmentation|up-regulation of adult chitin-containing cuticle pigmentation|upregulation of adult chitin-containing cuticle pigmentation|stimulation of adult chitin-containing cuticle pigmentation													biological_process											owl:Class	
GO:0021615	biolink:NamedThing	glossopharyngeal nerve morphogenesis	The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	got7fsn_ti	CN IX morphogenesis													biological_process											owl:Class	
GO:0021563	biolink:NamedThing	glossopharyngeal nerve development	Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	got7fsn_ti	CN IX development|cranial nerve 9 development|cranial nerve IX development													biological_process											owl:Class	
GO:1905662	biolink:NamedThing	negative regulation of telomerase RNA reverse transcriptase activity	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.	got7fsn_ti	inhibition of telomerase, catalyst|down regulation of telomerase RNA reverse transcriptase activity|downregulation of telomerase RNA reverse transcriptase activity|down-regulation of telomerase RNA reverse transcriptase activity|inhibition of telomerase RNA reverse transcriptase activity|downregulation of telomerase, catalyst|negative regulation of telomerase, catalyst|down-regulation of telomerase, catalyst|down regulation of telomerase, catalyst						nc	2016-11-09T16:55:28Z						biological_process											owl:Class	
GO:0008837	biolink:NamedThing	diaminopimelate epimerase activity	Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.	got7fsn_ti	LL-2,6-diaminoheptanedioate 2-epimerase activity											MetaCyc:DIAMINOPIMEPIM-RXN|RHEA:15393|EC:5.1.1.7|KEGG_REACTION:R02735		molecular_function											owl:Class	
GO:0120121	biolink:NamedThing	tripartite attachment complex	A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body.	got7fsn_ti	TAC						krc	2017-12-12T00:07:37Z						cellular_component											owl:Class	
GO:0035001	biolink:NamedThing	dorsal trunk growth, open tracheal system	Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system.	got7fsn_ti	dorsal trunk growth													biological_process											owl:Class	
GO:1903298	biolink:NamedThing	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.	got7fsn_ti	inhibition of intrinsic apoptotic signaling pathway in response to hypoxia|down-regulation of intrinsic apoptotic signaling pathway in response to hypoxia|protection against hypoxia-induced apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to hypoxia|negative regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway|negative regulation of hypoxia-induced apoptosis|negative regulation of intrinsic apoptotic signaling pathway in response to hypoxia|downregulation of intrinsic apoptotic signaling pathway in response to hypoxia						bf	2014-08-14T14:47:56Z						biological_process											owl:Class	
GO:0035218	biolink:NamedThing	leg disc development	Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.	got7fsn_ti														biological_process											owl:Class	
GO:0005537	biolink:NamedThing	mannose binding	Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.	got7fsn_ti	mannose binding lectin											Reactome:R-HSA-947991		molecular_function											owl:Class	
GO:0043012	biolink:NamedThing	regulation of fusion of sperm to egg plasma membrane	Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane.	got7fsn_ti	regulation of sperm-oocyte fusion													biological_process											owl:Class	
GO:1902897	biolink:NamedThing	regulation of postsynaptic density protein 95 clustering	Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.	got7fsn_ti	regulation of post-synaptic density protein 95 clustering|regulation of PSD-95 clustering|regulation of Dlg4 clustering						als	2014-04-09T14:52:08Z						biological_process											owl:Class	
GO:0038177	biolink:NamedThing	death receptor agonist activity	Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor.	got7fsn_ti	death receptor activator activity						bf	2012-09-20T12:52:00Z						molecular_function											owl:Class	
GO:0022851	biolink:NamedThing	GABA-gated chloride ion channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0019097	biolink:NamedThing	pole plasm mitochondrial srRNA localization	Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	got7fsn_ti	establishment and maintenance of mitochondrial localization in pole plasm|oocyte pole plasm mitochondrial srRNA localization|pole plasm mitochondrial srRNA localisation										GO:0048119			biological_process											owl:Class	
GO:0071100	biolink:NamedThing	alphaV-beta8 integrin-MMP14-TGFbeta-1 complex	A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).	got7fsn_ti	ITGAV-ITGB8-MMP14-TGFB1 complex						mah	2009-11-06T04:52:43Z						cellular_component											owl:Class	
GO:1902232	biolink:NamedThing	regulation of positive thymic T cell selection	Any process that modulates the frequency, rate or extent of positive thymic T cell selection.	got7fsn_ti	regulation of positive thymic T-lymphocyte selection|regulation of positive thymic T lymphocyte selection|regulation of positive thymic T-cell selection						lb	2013-06-14T11:19:09Z						biological_process											owl:Class	
GO:0006406	biolink:NamedThing	mRNA export from nucleus	The directed movement of mRNA from the nucleus to the cytoplasm.	got7fsn_ti	mRNA-nucleus export|mRNA export from cell nucleus|mRNA transport from nucleus to cytoplasm|mRNA export out of nucleus													biological_process											owl:Class	
GO:0060481	biolink:NamedThing	lobar bronchus epithelium development	The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.	got7fsn_ti														biological_process											owl:Class	
GO:0033230	biolink:NamedThing	ABC-type cysteine transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out).	got7fsn_ti	ATP-dependent cysteine transporter activity|ATPase-coupled cysteine transmembrane transporter activity|cysteine-exporting ATPase activity|cysteine-transporting ATPase activity|cysteine exporter|ATPase-coupled cysteine transporter activity	https://github.com/geneontology/go-ontology/issues/17289									GO:0032519			molecular_function											owl:Class	
GO:1903712	biolink:NamedThing	cysteine transmembrane transport	The directed movement of cysteine across a membrane.	got7fsn_ti							vw	2014-12-06T08:15:06Z						biological_process											owl:Class	
CHEBI:58165	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043549	biolink:NamedThing	regulation of kinase activity	Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0060682	biolink:NamedThing	primary ureteric bud growth	The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.	got7fsn_ti							dph	2009-06-02T02:56:01Z						biological_process											owl:Class	
GO:0035379	biolink:NamedThing	carbon dioxide transmembrane transporter activity	Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.	got7fsn_ti							bf	2010-03-18T11:19:38Z				Reactome:R-HSA-1247649|Reactome:R-HSA-1237069|Reactome:R-HSA-1237042|Reactome:R-HSA-1247645		molecular_function											owl:Class	
GO:0035378	biolink:NamedThing	carbon dioxide transmembrane transport	The process in which carbon dioxide (CO2) is transported across a membrane.	got7fsn_ti	carbon dioxide membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-18T11:17:54Z						biological_process											owl:Class	
GO:0060440	biolink:NamedThing	trachea formation	The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.	got7fsn_ti														biological_process											owl:Class	
GO:0043506	biolink:NamedThing	regulation of JUN kinase activity	Any process that modulates the frequency, rate or extent of JUN kinase activity.	got7fsn_ti	regulation of JUNK activity													biological_process											owl:Class	
GO:0090139	biolink:NamedThing	mitochondrial DNA packaging	Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure.	got7fsn_ti							tb	2009-12-08T02:12:19Z						biological_process											owl:Class	
GO:1900260	biolink:NamedThing	negative regulation of RNA-directed 5'-3' RNA polymerase activity	Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.	got7fsn_ti	inhibition of phage f2 replicase|down-regulation of PB2 proteins|down-regulation of RNA synthetase activity|down regulation of Q-beta replicase activity|downregulation of transcriptase|down regulation of PB2 proteins|negative regulation of 3D polymerase activity|down regulation of RNA synthetase activity|downregulation of RNA synthetase activity|negative regulation of RNA nucleotidyltransferase (RNA-directed) activity|down regulation of polymerase L|down-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|downregulation of ribonucleic replicase activity|down regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|inhibition of RNA-dependent RNA polymerase activity|downregulation of RNA-dependent RNA polymerase activity|down-regulation of RNA-dependent RNA polymerase activity|down-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|down regulation of RNA nucleotidyltransferase (RNA-directed) activity|downregulation of RNA-directed RNA polymerase activity|down regulation of transcriptase|negative regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|down-regulation of ribonucleic replicase activity|inhibition of polymerase L|negative regulation of RNA synthetase activity|inhibition of ribonucleic replicase activity|negative regulation of ribonucleic replicase activity|down regulation of 3D polymerase activity|down-regulation of RDRP|downregulation of PB2 proteins|downregulation of polymerase L|inhibition of RNA nucleotidyltransferase (RNA-directed) activity|negative regulation of RNA-directed RNA polymerase activity|down regulation of ribonucleic acid replicase activity|downregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|negative regulation of PB2 proteins|downregulation of RNA replicase activity|inhibition of ribonucleic acid replicase activity|inhibition of RDRP|down regulation of RDRP|downregulation of RNA nucleotidyltransferase (RNA-directed) activity|down-regulation of 3D polymerase activity|negative regulation of RNA replicase activity|down regulation of ribonucleic replicase activity|down-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|inhibition of PB1 proteins|negative regulation of PB1 proteins|down-regulation of RNA-directed RNA polymerase activity|inhibition of Q-beta replicase activity|negative regulation of ribonucleic acid replicase activity|inhibition of PB2 proteins|down-regulation of transcriptase|down-regulation of RNA-dependent RNA replicase activity|down-regulation of polymerase L|down-regulation of phage f2 replicase|negative regulation of phage f2 replicase|down-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down-regulation of RNA replicase activity|negative regulation of Q-beta replicase activity|negative regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|negative regulation of RNA-dependent RNA polymerase activity|downregulation of RNA-dependent RNA replicase activity|down-regulation of PB1 proteins|down regulation of phage f2 replicase|downregulation of Q-beta replicase activity|downregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|negative regulation of RNA-dependent RNA replicase activity|downregulation of RDRP|downregulation of PB1 proteins|inhibition of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|inhibition of RNA replicase activity|negative regulation of RDRP|downregulation of ribonucleic synthetase activity|inhibition of RNA-dependent RNA replicase activity|inhibition of RNA-dependent ribonucleate nucleotidyltransferase activity|down regulation of RNA-dependent RNA polymerase activity|downregulation of 3D polymerase activity|down regulation of ribonucleic synthetase activity|negative regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|downregulation of phage f2 replicase|down-regulation of ribonucleic acid replicase activity|down regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|inhibition of RNA-directed RNA polymerase activity|down regulation of RNA replicase activity|inhibition of transcriptase|down regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|negative regulation of transcriptase|negative regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|inhibition of RNA synthetase activity|down-regulation of ribonucleic synthetase activity|downregulation of RNA-dependent ribonucleate nucleotidyltransferase activity|downregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down regulation of RNA-directed RNA polymerase activity|inhibition of 3D polymerase activity|down-regulation of RNA nucleotidyltransferase (RNA-directed) activity|inhibition of ribonucleic synthetase activity|down regulation of PB1 proteins|negative regulation of polymerase L|inhibition of ribonucleic acid-dependent ribonucleic acid polymerase activity|down regulation of RNA-dependent RNA replicase activity|down-regulation of Q-beta replicase activity|downregulation of ribonucleic acid replicase activity|inhibition of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|negative regulation of ribonucleic synthetase activity						tb	2012-04-03T11:02:03Z						biological_process											owl:Class	
GO:0005745	biolink:NamedThing	m-AAA complex	Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria.	got7fsn_ti														cellular_component											owl:Class	
GO:0097736	biolink:NamedThing	aerial mycelium formation	The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae.	got7fsn_ti	fertile mycelium formation|aerial hyphal growth						pr	2016-10-14T14:25:22Z						biological_process											owl:Class	
GO:0005183	biolink:NamedThing	gonadotropin hormone-releasing hormone activity	The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary.	got7fsn_ti	LHRH activity|gonadotrophin hormone-releasing hormone activity|luteinizing hormone/follicle-stimulating hormone releasing factor activity|luteinizing hormone-releasing hormone activity|GnRH activity|LH/FSH-RF|luteinizing hormone-releasing factor activity													molecular_function											owl:Class	
GO:0006540	biolink:NamedThing	glutamate decarboxylation to succinate	The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.	got7fsn_ti	gamma-aminobutyrate shunt|glutamate degradation via 4-aminobutyrate|glutamate degradation via GABA|GABA shunt|degradation of glutamate to succinate through GABA|4-aminobutyrate shunt				Note that the third step in this pathway (conversion of succinate semialdehyde to succinate) can be catalyzed by NAD-dependent or NADP-dependent succinate semialdehyde dehydrogenase (EC:1.2.1.24 and EC:1.2.1.79, respectively).							MetaCyc:PWY-4321|MetaCyc:GLUDEG-I-PWY|MetaCyc:PWY3O-210		biological_process											owl:Class	
GO:0016558	biolink:NamedThing	protein import into peroxisome matrix	The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.	got7fsn_ti	protein transport to peroxisome matrix|peroxisome matrix protein import													biological_process											owl:Class	
GO:0010521	biolink:NamedThing	telomerase inhibitor activity	Binds to and stops, prevents or reduces the activity of telomerase.	got7fsn_ti														molecular_function											owl:Class	
GO:0015150	biolink:NamedThing	fucose transmembrane transporter activity	Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.	got7fsn_ti														molecular_function											owl:Class	
GO:0015756	biolink:NamedThing	fucose transmembrane transport	The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.	got7fsn_ti	fucose transport													biological_process											owl:Class	
GO:1901835	biolink:NamedThing	positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.	got7fsn_ti	activation of deadenylylation-independent decapping|activation of deadenylation-independent decapping of nuclear-transcribed mRNA|upregulation of deadenylation-independent decapping of nuclear mRNA|up regulation of deadenylation-independent decapping of nuclear-transcribed mRNA|positive regulation of deadenylylation-independent decapping|upregulation of deadenylation-independent decapping of nuclear-transcribed mRNA|up regulation of deadenylation-independent decapping of nuclear mRNA|up-regulation of deadenylation-independent decapping of nuclear mRNA|up regulation of deadenylylation-independent decapping|up-regulation of deadenylylation-independent decapping|activation of deadenylation-independent decapping of nuclear mRNA|positive regulation of deadenylation-independent decapping of nuclear mRNA|up-regulation of deadenylation-independent decapping of nuclear-transcribed mRNA|upregulation of deadenylylation-independent decapping						al	2013-01-22T22:42:22Z						biological_process											owl:Class	
GO:1905955	biolink:NamedThing	negative regulation of endothelial tube morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis.	got7fsn_ti	down regulation of endothelial tube morphogenesis|down-regulation of endothelial tube morphogenesis|downregulation of endothelial tube morphogenesis|inhibition of endothelial tube morphogenesis						rph	2017-02-21T15:17:31Z						biological_process											owl:Class	
GO:0070164	biolink:NamedThing	negative regulation of adiponectin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.	got7fsn_ti	inhibition of adiponectin secretion|downregulation of adiponectin secretion|down-regulation of adiponectin secretion|down regulation of adiponectin secretion													biological_process											owl:Class	
GO:0021941	biolink:NamedThing	negative regulation of cerebellar granule cell precursor proliferation	The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation.	got7fsn_ti	inhibition of granule cell precursor proliferation|down-regulation of granule cell precursor proliferation|downregulation of granule cell precursor proliferation|down regulation of granule cell precursor proliferation													biological_process											owl:Class	
GO:0032931	biolink:NamedThing	histone acetyltransferase activity (H3-K56 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K56 specific)													molecular_function											owl:Class	
GO:0005579	biolink:NamedThing	membrane attack complex	A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.	got7fsn_ti	TCC|MAC|membrane attack complex protein beta2 chain|terminal complement complex|membrane attack complex protein alphaM chain											Wikipedia:Complement_membrane_attack_complex		cellular_component											owl:Class	
GO:1902902	biolink:NamedThing	negative regulation of autophagosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.	got7fsn_ti	inhibition of PAS formation|downregulation of autophagosome biosynthesis|down-regulation of autophagosome formation|down-regulation of PAS formation|down-regulation of autophagosome biosynthesis|downregulation of autophagic vacuole assembly|down-regulation of autophagic vacuole assembly|inhibition of autophagosome formation|inhibition of autophagosome biosynthesis|inhibition of autophagic vacuole formation|down regulation of autophagosome biosynthesis|negative regulation of autophagosome biosynthesis|down regulation of autophagosome formation|negative regulation of autophagosome formation|down regulation of autophagic vacuole formation|down regulation of autophagic vacuole assembly|down-regulation of autophagic vacuole formation|downregulation of autophagosome formation|negative regulation of autophagic vacuole formation|downregulation of autophagic vacuole formation|down regulation of PAS formation|negative regulation of autophagic vacuole assembly|negative regulation of PAS formation|downregulation of PAS formation|inhibition of autophagic vacuole assembly						als	2014-04-15T10:37:40Z						biological_process											owl:Class	
GO:0015421	biolink:NamedThing	ABC-type oligopeptide transporter activity	Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in).	got7fsn_ti	ATPase-coupled oligopeptide transmembrane transporter activity|ATP-dependent oligopeptide transmembrane transporter activity|oligopeptide ABC transporter|oligopeptide permease activity|ABC-type oligopeptide transporter|oligopeptide-transporting ATPase activity											MetaCyc:3.6.3.23-RXN|Reactome:R-HSA-5223317|RHEA:37271|EC:7.4.2.6		molecular_function											owl:Class	
GO:0035672	biolink:NamedThing	oligopeptide transmembrane transport	The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	got7fsn_ti	oligopeptide membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2011-02-08T02:18:07Z						biological_process											owl:Class	
GO:0006335	biolink:NamedThing	DNA replication-dependent nucleosome assembly	The formation of nucleosomes on newly replicated DNA, coupled to strand elongation.	got7fsn_ti														biological_process											owl:Class	
GO:0009345	biolink:NamedThing	glycine-tRNA ligase complex	A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly).	got7fsn_ti	glycine-tRNA synthetase complex													cellular_component											owl:Class	
GO:2000718	biolink:NamedThing	regulation of maintenance of mitotic sister chromatid cohesion, centromeric	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.	got7fsn_ti	regulation of maintenance of centromeric mitotic sister chromatin cohesion|regulation of maintenance of mitotic sister chromatin cohesion at centromere|regulation of maintenance of sister chromatin cohesion at centromere at mitosis						mah	2011-06-03T10:41:11Z						biological_process											owl:Class	
GO:0061354	biolink:NamedThing	planar cell polarity pathway involved in pericardium morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.	got7fsn_ti							dph	2010-10-01T03:12:53Z						biological_process											owl:Class	
GO:0003344	biolink:NamedThing	pericardium morphogenesis	The process in which the anatomical structure of the pericardium is generated and organized.	got7fsn_ti							dph	2009-12-01T10:46:34Z						biological_process											owl:Class	
GO:0000085	biolink:NamedThing	mitotic G2 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.	got7fsn_ti	G2 phase of mitotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:2001189	biolink:NamedThing	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.	got7fsn_ti	negative regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell						yaf	2011-11-03T01:31:36Z						biological_process											owl:Class	
GO:0000239	biolink:NamedThing	pachytene	The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Meiosis#Pachytene|Wikipedia:Pachytene		biological_process											owl:Class	
GO:1905470	biolink:NamedThing	positive regulation of clathrin-coated pit assembly	Any process that activates or increases the frequency, rate or extent of clathrin-coated pit assembly.	got7fsn_ti	up-regulation of clathrin-coated pit formation|activation of coated pit assembly|up-regulation of clathrin-coated pit assembly|up regulation of coated pit formation|up regulation of coated pit assembly|positive regulation of coated pit assembly|up-regulation of coated pit assembly|up regulation of clathrin-coated pit assembly|activation of clathrin-coated pit assembly|positive regulation of coated pit formation|upregulation of coated pit formation|up-regulation of coated pit formation|positive regulation of clathrin-coated pit formation|upregulation of coated pit assembly|activation of clathrin-coated pit formation|up regulation of clathrin-coated pit formation|upregulation of clathrin-coated pit assembly|upregulation of clathrin-coated pit formation|activation of coated pit formation						bf	2016-09-20T10:04:53Z						biological_process											owl:Class	
GO:0016557	biolink:NamedThing	peroxisome membrane biogenesis	The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.	got7fsn_ti														biological_process											owl:Class	
GO:0030129	biolink:NamedThing	clathrin coat of synaptic vesicle	A clathrin coat found on a synaptic vesicle.	got7fsn_ti														cellular_component											owl:Class	
GO:0061907	biolink:NamedThing	negative regulation of AMPA receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity.	got7fsn_ti							dph	2017-06-29T11:55:11Z						biological_process											owl:Class	
GO:0005524	biolink:NamedThing	ATP binding	Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	got7fsn_ti												Reactome:R-HSA-265682		molecular_function											owl:Class	
GO:1901395	biolink:NamedThing	regulation of transforming growth factor beta2 activation	Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation.	got7fsn_ti	regulation of TGFB2 activation|regulation of TGFbeta 2 activation|regulation of TGF-beta 2 activation						bf	2012-10-01T10:46:50Z						biological_process											owl:Class	
GO:0120228	biolink:NamedThing	outer dynein arm docking complex	A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules.	got7fsn_ti	ODA-DC|ODA docking complex	https://github.com/geneontology/go-ontology/issues/19588					krc	2020-06-05T23:30:44Z						cellular_component											owl:Class	
GO:0016546	biolink:NamedThing	male courtship behavior, proboscis-mediated licking	The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster.	got7fsn_ti	male courtship behavior, licking|male courtship behaviour, proboscis-mediated licking|male courtship behaviour, licking													biological_process											owl:Class	
GO:0070806	biolink:NamedThing	negative regulation of phialide development	Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.	got7fsn_ti							mah	2009-07-08T04:47:16Z						biological_process											owl:Class	
GO:0000958	biolink:NamedThing	mitochondrial mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion.	got7fsn_ti														biological_process											owl:Class	
GO:0060582	biolink:NamedThing	cell fate determination involved in pattern specification	A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	got7fsn_ti							dph	2009-05-07T12:48:08Z						biological_process											owl:Class	
GO:0098647	biolink:NamedThing	collagen beaded filament	A supramolecular assembly of collagen trimers with a 'beads on a string'-like structure.	got7fsn_ti	beads on a string													cellular_component											owl:Class	
GO:0033172	biolink:NamedThing	gas vesicle shell	The proteinaceous structure surrounding a gas vesicle.	got7fsn_ti	gas vesicle membrane|gas vesicle wall													cellular_component											owl:Class	
GO:0006363	biolink:NamedThing	termination of RNA polymerase I transcription	The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit.	got7fsn_ti	termination of RNA polymerase I transcription from promoter for nuclear large rRNA transcript|transcription termination from Pol I promoter|RNA polymerase I transcription termination|transcription termination from RNA polymerase I promoter|RNA polymerase I transcription termination factor activity						krc	2011-08-15T04:07:43Z			GO:0001185|GO:0019223			biological_process											owl:Class	
GO:0018109	biolink:NamedThing	peptidyl-arginine phosphorylation	The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine.	got7fsn_ti												RESID:AA0222		biological_process											owl:Class	
GO:0017077	biolink:NamedThing	oxidative phosphorylation uncoupler activity	Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.	got7fsn_ti	uncoupling protein activity|mitochondrial uncoupling protein activity										GO:0015302			molecular_function											owl:Class	
GO:0052776	biolink:NamedThing	diacetylchitobiose catabolic process to glucosamine and acetate	The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate.	got7fsn_ti														biological_process											owl:Class	
GO:0043515	biolink:NamedThing	kinetochore binding	Binding to a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached.	got7fsn_ti														molecular_function											owl:Class	
GO:0120017	biolink:NamedThing	ceramide transfer activity	Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	ceramide transporter activity|ceramide carrier activity|intermembrane ceramide transfer activity	https://github.com/geneontology/go-ontology/issues/12329					krc	2010-12-08T12:32:50Z			GO:0035620			molecular_function											owl:Class	
GO:0097001	biolink:NamedThing	ceramide binding	Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.	got7fsn_ti							pr	2011-03-09T11:34:09Z						molecular_function											owl:Class	
GO:0002623	biolink:NamedThing	negative regulation of B cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.	got7fsn_ti	down-regulation of B cell antigen processing and presentation|downregulation of B cell antigen processing and presentation|inhibition of B cell antigen processing and presentation|down regulation of B cell antigen processing and presentation|negative regulation of B lymphocyte antigen processing and presentation|negative regulation of B-cell antigen processing and presentation|negative regulation of B-lymphocyte antigen processing and presentation													biological_process											owl:Class	
GO:0003322	biolink:NamedThing	pancreatic A cell development	The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.	got7fsn_ti	pancreatic alpha cell development						dph	2009-11-02T08:13:55Z						biological_process											owl:Class	
GO:0003310	biolink:NamedThing	pancreatic A cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.	got7fsn_ti	pancreatic alpha cell differentiation						dph	2009-10-26T09:28:05Z						biological_process											owl:Class	
GO:0002905	biolink:NamedThing	regulation of mature B cell apoptotic process	Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.	got7fsn_ti	regulation of mature B cell apoptosis													biological_process											owl:Class	
CL:0000120	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070498	biolink:NamedThing	interleukin-1-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-1 beta-mediated signaling pathway|interleukin-1 beta-mediated signaling pathway|IL-1-mediated signaling pathway|IL-1 alpha-mediated signaling pathway|interleukin-1 alpha-mediated signaling pathway|interleukin-1-mediated signalling pathway													biological_process											owl:Class	
GO:0016183	biolink:NamedThing	synaptic vesicle coating	The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:0016185	biolink:NamedThing	synaptic vesicle budding from presynaptic endocytic zone membrane	Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle.	got7fsn_ti	synaptic vesicle budding from pre-synaptic membrane|synaptic vesicle budding involved in synaptic vesicle endocytosis													biological_process											owl:Class	
GO:0006353	biolink:NamedThing	DNA-templated transcription, termination	The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.	got7fsn_ti	DNA-dependent transcription, termination|termination of DNA-dependent transcription|termination of transcription, DNA-dependent|transcription termination, DNA-dependent|transcription termination factor activity|transcriptional complex disassembly													biological_process											owl:Class	
GO:0032414	biolink:NamedThing	positive regulation of ion transmembrane transporter activity	Any process that activates or increases the activity of an ion transporter.	got7fsn_ti	up regulation of ion transporter activity|upregulation of ion transporter activity|activation of ion transporter activity|stimulation of ion transporter activity|positive regulation of ion transporter activity|up-regulation of ion transporter activity													biological_process											owl:Class	
GO:0061535	biolink:NamedThing	glutamate secretion, neurotransmission	The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter.	got7fsn_ti							dph	2013-06-21T16:14:47Z						biological_process											owl:Class	
GO:2000232	biolink:NamedThing	regulation of rRNA processing	Any process that modulates the frequency, rate or extent of rRNA processing.	got7fsn_ti	regulation of 35S primary transcript processing						mah	2010-11-10T12:11:29Z						biological_process											owl:Class	
CL:0000182	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905792	biolink:NamedThing	positive regulation of mechanosensory behavior	Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.	got7fsn_ti	up regulation of mechanosensory behaviour|up-regulation of mechanosensory behavior|up-regulation of behavioural response to mechanical stimulus|up-regulation of behavioral response to mechanical stimulus|up regulation of behavioral response to mechanical stimulus|positive regulation of mechanosensory behaviour|upregulation of mechanosensory behavior|upregulation of behavioral response to mechanical stimulus|up regulation of mechanosensory behavior|positive regulation of behavioral response to mechanical stimulus|positive regulation of behavioural response to mechanical stimulus|up-regulation of mechanosensory behaviour|upregulation of mechanosensory behaviour|activation of mechanosensory behaviour|up regulation of behavioural response to mechanical stimulus|activation of mechanosensory behavior|activation of behavioral response to mechanical stimulus|upregulation of behavioural response to mechanical stimulus|activation of behavioural response to mechanical stimulus						hbye	2017-01-09T15:17:24Z						biological_process											owl:Class	
GO:0002804	biolink:NamedThing	positive regulation of antifungal peptide production	Any process that activates or increases the frequency, rate, or extent of antifungal peptide production.	got7fsn_ti	stimulation of antifungal peptide production|activation of antifungal peptide production|upregulation of antifungal peptide production|up-regulation of antifungal peptide production|up regulation of antifungal peptide production													biological_process											owl:Class	
GO:2001011	biolink:NamedThing	positive regulation of plant-type cell wall cellulose biosynthetic process	Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.	got7fsn_ti	positive regulation of cellulose biosynthesis during cell wall biosynthesis|positive regulation of cell wall cellulose biosynthesis						tt	2011-08-08T08:47:30Z						biological_process											owl:Class	
GO:2000792	biolink:NamedThing	positive regulation of mesenchymal cell proliferation involved in lung development	Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.	got7fsn_ti							pr	2011-06-24T01:53:56Z						biological_process											owl:Class	
GO:0035175	biolink:NamedThing	histone kinase activity (H3-S10 specific)	Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3.	got7fsn_ti	histone-serine kinase activity (H3-S10 specific)|histone serine kinase activity (H3-S10 specific)|histone kinase activity (H3-S3 specific)										GO:0044021			molecular_function											owl:Class	
GO:0002783	biolink:NamedThing	antifungal peptide biosynthetic process	The chemical reactions and pathways resulting in the formation of an antifungal peptide.	got7fsn_ti														biological_process											owl:Class	
GO:0022016	biolink:NamedThing	pallium glioblast division	The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells.	got7fsn_ti	glioblast cell division in pallium													biological_process											owl:Class	
GO:0033088	biolink:NamedThing	negative regulation of immature T cell proliferation in thymus	Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.	got7fsn_ti	negative regulation of thymocyte proliferation|negative regulation of thymic T cell proliferation|negative regulation of thymocyte cell proliferation													biological_process											owl:Class	
GO:2001222	biolink:NamedThing	regulation of neuron migration	Any process that modulates the frequency, rate or extent of neuron migration.	got7fsn_ti	regulation of neuron guidance|regulation of neuronal migration|regulation of neuron chemotaxis						kmv	2011-11-17T10:01:38Z						biological_process											owl:Class	
GO:0050885	biolink:NamedThing	neuromuscular process controlling balance	Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.	got7fsn_ti	regulation of balance													biological_process											owl:Class	
GO:0001552	biolink:NamedThing	ovarian follicle atresia	A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed.	got7fsn_ti														biological_process											owl:Class	
UBERON:0001305	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0095500	biolink:NamedThing	acetylcholine receptor signaling pathway	The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.	got7fsn_ti	acetylcholine receptor signalling pathway													biological_process											owl:Class	
GO:1905145	biolink:NamedThing	cellular response to acetylcholine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.	got7fsn_ti							dos	2016-04-14T08:54:58Z						biological_process											owl:Class	
GO:0061557	biolink:NamedThing	trigeminal ganglion maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.	got7fsn_ti	trigeminal ganglia maturation						dph	2013-07-10T08:58:24Z						biological_process											owl:Class	
GO:0072562	biolink:NamedThing	blood microparticle	A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.	got7fsn_ti	cell membrane microparticle						mah	2011-01-28T11:50:56Z						cellular_component											owl:Class	
GO:1903106	biolink:NamedThing	positive regulation of insulin receptor signaling pathway involved in determination of adult lifespan	Any process that activates or increases the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.	got7fsn_ti	up-regulation of daf-2 receptor signaling pathway of determination of adult lifespan|activation of insulin receptor signalling pathway of determination of adult lifespan|up regulation of insulin receptor signaling pathway of determination of adult lifespan|up regulation of insulin receptor signalling pathway of determination of adult lifespan|up-regulation of insulin receptor signaling pathway of determination of adult lifespan|positive regulation of insulin receptor signalling pathway of determination of adult lifespan|upregulation of insulin receptor signaling pathway of determination of adult lifespan|upregulation of daf-2 receptor signaling pathway of determination of adult lifespan|upregulation of insulin receptor signalling pathway of determination of adult lifespan|activation of insulin receptor signaling pathway of determination of adult lifespan|upregulation of insulin receptor signaling pathway involved in determination of adult lifespan|activation of daf-2 receptor signaling pathway of determination of adult lifespan|up regulation of insulin receptor signaling pathway involved in determination of adult lifespan|activation of insulin receptor signaling pathway involved in determination of adult lifespan|positive regulation of insulin receptor signaling pathway of determination of adult lifespan|up-regulation of insulin receptor signalling pathway of determination of adult lifespan|up-regulation of insulin receptor signaling pathway involved in determination of adult lifespan|positive regulation of daf-2 receptor signaling pathway of determination of adult lifespan|up regulation of daf-2 receptor signaling pathway of determination of adult lifespan						kmv	2014-06-05T20:56:19Z						biological_process											owl:Class	
GO:0051972	biolink:NamedThing	regulation of telomerase activity	Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.	got7fsn_ti	telomerase regulator													biological_process											owl:Class	
GO:0043850	biolink:NamedThing	RecFOR complex	A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair.	got7fsn_ti														cellular_component											owl:Class	
GO:1903052	biolink:NamedThing	positive regulation of proteolysis involved in cellular protein catabolic process	Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.	got7fsn_ti	up-regulation of proteolysis involved in cellular protein catabolic process|up regulation of peptidolysis involved in cellular protein catabolic process|up regulation of peptidolysis during cellular protein catabolic process|activation of proteolysis during cellular protein catabolism|positive regulation of peptidolysis during cellular protein catabolism|upregulation of peptidolysis during cellular protein catabolism|up-regulation of peptidolysis involved in cellular protein catabolic process|up regulation of peptidolysis during cellular protein catabolism|positive regulation of peptidolysis involved in cellular protein catabolism|activation of peptidolysis during cellular protein catabolism|activation of peptidolysis during cellular protein catabolic process|upregulation of peptidolysis involved in cellular protein catabolism|up-regulation of proteolysis during cellular protein catabolism|activation of peptidolysis involved in cellular protein catabolism|up regulation of proteolysis during cellular protein catabolic process|upregulation of peptidolysis involved in cellular protein catabolic process|upregulation of proteolysis during cellular protein catabolism|upregulation of proteolysis involved in cellular protein catabolic process|up regulation of peptidolysis involved in cellular protein catabolism|up-regulation of peptidolysis involved in cellular protein catabolism|activation of proteolysis during cellular protein catabolic process|up-regulation of proteolysis during cellular protein catabolic process|positive regulation of peptidolysis during cellular protein catabolic process|positive regulation of proteolysis during cellular protein catabolism|up regulation of proteolysis involved in cellular protein catabolic process|up-regulation of peptidolysis during cellular protein catabolic process|upregulation of peptidolysis during cellular protein catabolic process|upregulation of proteolysis during cellular protein catabolic process|up-regulation of peptidolysis during cellular protein catabolism|activation of peptidolysis involved in cellular protein catabolic process|positive regulation of proteolysis during cellular protein catabolic process|up regulation of proteolysis during cellular protein catabolism|positive regulation of peptidolysis involved in cellular protein catabolic process|activation of proteolysis involved in cellular protein catabolic process				overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)		rl	2014-05-22T18:00:57Z						biological_process											owl:Class	
GO:1905068	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in heart development	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.	got7fsn_ti	up-regulation of canonical Wnt signaling pathway involved in heart development|up regulation of canonical Wnt-activated signaling pathway involved in heart development|up regulation of canonical Wnt signaling pathway involved in heart development|up regulation of canonical Wnt receptor signalling pathway involved in heart development|positive regulation of canonical Wnt receptor signalling pathway involved in heart development|activation of canonical Wnt signaling pathway involved in heart development|up-regulation of canonical Wnt-activated signaling pathway involved in heart development|activation of canonical Wnt receptor signalling pathway involved in heart development|activation of canonical Wnt receptor signaling pathway involved in heart development|up regulation of canonical Wnt receptor signaling pathway involved in heart development|upregulation of canonical Wnt signaling pathway involved in heart development|activation of canonical Wnt-activated signaling pathway involved in heart development|up-regulation of canonical Wnt receptor signaling pathway involved in heart development|up-regulation of canonical Wnt receptor signalling pathway involved in heart development|upregulation of canonical Wnt receptor signalling pathway involved in heart development|upregulation of canonical Wnt-activated signaling pathway involved in heart development|upregulation of canonical Wnt receptor signaling pathway involved in heart development|positive regulation of canonical Wnt-activated signaling pathway involved in heart development|positive regulation of canonical Wnt receptor signaling pathway involved in heart development						bc	2016-03-21T12:47:15Z						biological_process											owl:Class	
GO:0060598	biolink:NamedThing	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis	The process in which the terminal end of a mammary duct bifurcates.	got7fsn_ti	primary mammary duct branching						dph	2009-05-13T12:16:29Z						biological_process											owl:Class	
GO:0002799	biolink:NamedThing	positive regulation of antibacterial peptide secretion	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion.	got7fsn_ti	up regulation of antibacterial peptide secretion|up-regulation of antibacterial peptide secretion|activation of antibacterial peptide secretion|stimulation of antibacterial peptide secretion|upregulation of antibacterial peptide secretion													biological_process											owl:Class	
GO:0090636	biolink:NamedThing	outer dense plaque of desmosome	The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins,  as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane.	got7fsn_ti							tb	2015-04-20T16:10:51Z						cellular_component											owl:Class	
GO:0021704	biolink:NamedThing	locus ceruleus morphogenesis	The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.	got7fsn_ti														biological_process											owl:Class	
GO:0010995	biolink:NamedThing	free ubiquitin chain depolymerization	The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down.	got7fsn_ti							tb	2009-06-03T11:45:42Z						biological_process											owl:Class	
GO:0010992	biolink:NamedThing	ubiquitin recycling	Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates.	got7fsn_ti	regulation of ubiquitin homeostasis|ubiquitin homeostasis						tb	2009-06-03T11:36:55Z			GO:0010993			biological_process											owl:Class	
GO:0030174	biolink:NamedThing	regulation of DNA-dependent DNA replication initiation	Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.	got7fsn_ti	regulation of DNA replication initiation|DNA replication licencing|DNA replication licensing													biological_process											owl:Class	
GO:0003909	biolink:NamedThing	DNA ligase activity	Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.	got7fsn_ti												Reactome:R-HSA-6782227|Reactome:R-HSA-5693604|Reactome:R-HSA-5690997|Reactome:R-HSA-69173|Reactome:R-HSA-174456|Reactome:R-HSA-73931|Reactome:R-HSA-5358592|Reactome:R-HSA-5687675|Reactome:R-HSA-5649734|Reactome:R-HSA-175258|Reactome:R-HSA-5651789|Reactome:R-HSA-5651805		molecular_function											owl:Class	
GO:0036301	biolink:NamedThing	macrophage colony-stimulating factor production	The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	M-CSF production						bf	2012-08-07T14:07:13Z						biological_process											owl:Class	
GO:0042685	biolink:NamedThing	cardioblast cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti														biological_process											owl:Class	
GO:0042684	biolink:NamedThing	cardioblast cell fate commitment	The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti														biological_process											owl:Class	
GO:0015611	biolink:NamedThing	ABC-type D-ribose transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in).	got7fsn_ti	D-ribose-importing ATPase activity|D-ribose porter activity											RHEA:29903|MetaCyc:ABC-28-RXN|EC:7.5.2.8		molecular_function											owl:Class	
GO:0070771	biolink:NamedThing	alphaIIb-beta3 integrin-CD47-Src complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.	got7fsn_ti	ITGA2b-ITGB3-CD47-SRC complex						mah	2009-06-29T05:46:53Z						cellular_component											owl:Class	
GO:1901018	biolink:NamedThing	positive regulation of potassium ion transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity.	got7fsn_ti	positive regulation of potassium transporter activity|upregulation of potassium transporter activity|activation of potassium ion transmembrane transporter activity|up regulation of potassium ion transmembrane transporter activity|upregulation of potassium ion transmembrane transporter activity|up regulation of potassium transporter activity|up-regulation of potassium ion transmembrane transporter activity|up-regulation of potassium transporter activity|activation of potassium transporter activity						rl	2012-06-15T01:14:18Z						biological_process											owl:Class	
GO:0003350	biolink:NamedThing	pulmonary myocardium development	The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.	got7fsn_ti							dph	2009-12-01T12:50:06Z						biological_process											owl:Class	
GO:0060841	biolink:NamedThing	venous blood vessel development	The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.	got7fsn_ti							dph	2009-08-12T10:14:07Z						biological_process											owl:Class	
GO:1903376	biolink:NamedThing	regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.	got7fsn_ti	regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|regulation of neuron apoptosis in response to oxidative stress|regulation of oxidative stress-induced neuronal apoptosis|regulation of oxidative stress-induced neuron apoptosis						bf	2014-08-26T13:03:13Z						biological_process											owl:Class	
GO:0010888	biolink:NamedThing	negative regulation of lipid storage	Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.	got7fsn_ti														biological_process											owl:Class	
GO:0072327	biolink:NamedThing	vulval cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.	got7fsn_ti							mah	2010-11-01T02:14:06Z						biological_process											owl:Class	
GO:0048539	biolink:NamedThing	bone marrow development	The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0000221	biolink:NamedThing	vacuolar proton-transporting V-type ATPase, V1 domain	The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.	got7fsn_ti	vacuolar hydrogen ion-transporting ATPase V1 domain				Note that this domain generally consists of eight subunits.									cellular_component											owl:Class	
GO:0016471	biolink:NamedThing	vacuolar proton-transporting V-type ATPase complex	A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.	got7fsn_ti	vacuolar hydrogen-translocating V-type ATPase complex				See also the cellular component terms 'vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221' and 'vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220' and the molecular function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'.									cellular_component											owl:Class	
GO:1905219	biolink:NamedThing	regulation of platelet formation	Any process that modulates the frequency, rate or extent of platelet formation.	got7fsn_ti	regulation of platelet extrusion						sl	2016-06-06T22:15:46Z						biological_process											owl:Class	
GO:1905206	biolink:NamedThing	positive regulation of hydrogen peroxide-induced cell death	Any process that activates or increases the frequency, rate or extent of cell death in response to hydrogen peroxide.	got7fsn_ti	up regulation of cell death in response to H2O2|up-regulation of cell death in response to H2O2|upregulation of cell death in response to hydrogen peroxide|positive regulation of cell death in response to hydrogen peroxide|up-regulation of hydrogen peroxide-mediated cell death|positive regulation of hydrogen peroxide-mediated cell death|up regulation of cell death in response to hydrogen peroxide|upregulation of hydrogen peroxide-mediated cell death|activation of hydrogen peroxide-mediated cell death|positive regulation of cell death in response to H2O2|up-regulation of cell death in response to hydrogen peroxide|up regulation of hydrogen peroxide-mediated cell death|activation of cell death in response to H2O2|upregulation of cell death in response to H2O2|activation of cell death in response to hydrogen peroxide						bc	2016-05-20T13:13:39Z						biological_process											owl:Class	
GO:0039594	biolink:NamedThing	endoribonuclease activity involved in viral induction of host mRNA catabolic process	Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA.	got7fsn_ti					GO:0039594 can be used to annotate a host or viral endoribonuclease activity that cleaves host mRNA in response to a viral infection.		bf	2012-07-05T11:21:26Z						molecular_function											owl:Class	
GO:0039599	biolink:NamedThing	cleavage by virus of host mRNA	Any process in which a host pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner by a viral endoribonuclease.	got7fsn_ti	viral endoribonuclease activity involved in degradation of host mRNA|host mRNA cleavage by viral endoribonuclease						bf	2012-07-04T05:09:08Z						biological_process											owl:Class	
GO:0043484	biolink:NamedThing	regulation of RNA splicing	Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.	got7fsn_ti														biological_process											owl:Class	
GO:0033597	biolink:NamedThing	mitotic checkpoint complex	A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.	got7fsn_ti	MCC													cellular_component											owl:Class	
GO:0051033	biolink:NamedThing	RNA transmembrane transporter activity	Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-203906		molecular_function											owl:Class	
GO:0048536	biolink:NamedThing	spleen development	The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.	got7fsn_ti														biological_process											owl:Class	
GO:0002800	biolink:NamedThing	regulation of antifungal peptide secretion	Any process that modulates the frequency, rate, or extent of antifungal peptide secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0003034	biolink:NamedThing	detection of increased carbon dioxide by aortic body chemoreceptor signaling	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body.	got7fsn_ti	detection of increased carbon dioxide by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:1903915	biolink:NamedThing	positive regulation of fusion of virus membrane with host plasma membrane	Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane.	got7fsn_ti	up-regulation of viral penetration via membrane fusion|positive regulation of viral envelope fusion with host membrane|upregulation of viral envelope fusion with host plasma membrane|up regulation of viral penetration via membrane fusion|upregulation of viral penetration via membrane fusion|up regulation of viral entry into host cell via membrane fusion with the plasma membrane|up-regulation of viral envelope fusion with host cell membrane|up-regulation of viral-cell fusion molecule activity|upregulation of viral-cell fusion molecule activity|activation of fusion of virus membrane with host plasma membrane|activation of viral-cell fusion molecule activity|up-regulation of fusion of virus membrane with host plasma membrane|up regulation of fusion of virus membrane with host plasma membrane|up-regulation of viral entry into host cell via membrane fusion with the plasma membrane|upregulation of viral entry into host cell via membrane fusion with the plasma membrane|positive regulation of viral envelope fusion with host plasma membrane|up regulation of viral-cell fusion molecule activity|activation of viral envelope fusion with host membrane|activation of viral envelope fusion with host plasma membrane|positive regulation of viral-cell fusion molecule activity|up-regulation of viral envelope fusion with host membrane|up regulation of viral envelope fusion with host cell membrane|up regulation of viral envelope fusion with host membrane|upregulation of viral envelope fusion with host cell membrane|up regulation of viral envelope fusion with host plasma membrane|positive regulation of viral entry into host cell via membrane fusion with the plasma membrane|up-regulation of viral envelope fusion with host plasma membrane|positive regulation of viral penetration via membrane fusion|activation of viral penetration via membrane fusion|activation of viral envelope fusion with host cell membrane|upregulation of viral envelope fusion with host membrane|positive regulation of viral envelope fusion with host cell membrane|activation of viral entry into host cell via membrane fusion with the plasma membrane|upregulation of fusion of virus membrane with host plasma membrane						als	2015-02-09T11:13:41Z						biological_process											owl:Class	
GO:0000959	biolink:NamedThing	mitochondrial RNA metabolic process	The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.	got7fsn_ti														biological_process											owl:Class	
GO:0090083	biolink:NamedThing	regulation of inclusion body assembly	Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	got7fsn_ti							tb	2009-10-23T11:07:22Z						biological_process											owl:Class	
GO:1905295	biolink:NamedThing	regulation of neural crest cell fate specification	Any process that modulates the frequency, rate or extent of neural crest cell fate specification.	got7fsn_ti							rl	2016-06-28T15:14:40Z						biological_process											owl:Class	
GO:0031065	biolink:NamedThing	positive regulation of histone deacetylation	Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.	got7fsn_ti	up regulation of histone deacetylation|activation of histone deacetylation|upregulation of histone deacetylation|up-regulation of histone deacetylation|stimulation of histone deacetylation													biological_process											owl:Class	
GO:0010719	biolink:NamedThing	negative regulation of epithelial to mesenchymal transition	Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti														biological_process											owl:Class	
GO:0072287	biolink:NamedThing	metanephric distal tubule morphogenesis	The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.	got7fsn_ti							mah	2010-04-09T03:41:47Z						biological_process											owl:Class	
GO:0061382	biolink:NamedThing	Malpighian tubule tip cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.	got7fsn_ti							dph	2010-11-23T09:52:44Z						biological_process											owl:Class	
GO:0048452	biolink:NamedThing	petal structural organization	The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	petal structural organisation										GO:0048420			biological_process											owl:Class	
GO:1903374	biolink:NamedThing	subarachnoid space development	The process whose specific outcome is the progression of a subarachnoid space over time, from its formation to the mature structure.	got7fsn_ti	subarachnoid cavity development|spatium subarachnoideum development|spatium leptomeningeum development|cavum subarachnoideale development|cavitas subarachnoidea development	https://github.com/geneontology/go-ontology/issues/21883					pr	2014-08-22T12:20:56Z						biological_process											owl:Class	
GO:0061139	biolink:NamedThing	bud field specification	The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti							dph	2010-05-25T09:21:01Z						biological_process											owl:Class	
GO:1904073	biolink:NamedThing	regulation of trophectodermal cell proliferation	Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation.	got7fsn_ti	regulation of trophectoderm cell proliferation						tb	2015-03-20T16:55:56Z						biological_process											owl:Class	
GO:0061442	biolink:NamedThing	cardiac muscle cell fate determination	The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	got7fsn_ti							dph	2012-03-13T08:59:57Z						biological_process											owl:Class	
GO:0039640	biolink:NamedThing	viral release by cytolysis via suppression of host peptidoglycan biosynthetic process	The killing by a virus of host cell by cytolysis, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.	got7fsn_ti	viral exit by cytolysis via suppression of host peptidoglycan biosynthetic process|cytolysis by virus via suppression of host peptidoglycan biosynthetic process	https://github.com/geneontology/go-ontology/issues/18852					bf	2012-08-17T10:54:55Z						biological_process											owl:Class	
GO:0003024	biolink:NamedThing	baroreceptor detection of decreased arterial stretch	The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0033289	biolink:NamedThing	intraconoid microtubule	A microtubule located such that it threads through the conoid and projects through the polar ring.	got7fsn_ti														cellular_component											owl:Class	
GO:0120168	biolink:NamedThing	detection of hot stimulus involved in thermoception	The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception.	got7fsn_ti	sensory transduction of hot stimulus during thermoception|thermoception, sensory transduction of hot stimulus|sensory transduction of heat stimulus during thermoception|sensory detection of heat stimulus during thermoception|thermoception, sensory detection of heat stimulus|sensory detection of hot stimulus during thermoception|thermoception, sensory detection of hot stimulus|thermoception, sensory transduction of heat stimulus						krc	2018-05-21T20:35:47Z						biological_process											owl:Class	
GO:0060315	biolink:NamedThing	negative regulation of ryanodine-sensitive calcium-release channel activity	Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														biological_process											owl:Class	
GO:0042700	biolink:NamedThing	luteinizing hormone signaling pathway	The series of molecular signals mediated by luteinizing hormone.	got7fsn_ti	luteinizing hormone signalling pathway													biological_process											owl:Class	
GO:0007398	biolink:NamedThing	ectoderm development	The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0043029	biolink:NamedThing	T cell homeostasis	The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti	T-cell homeostasis|T-lymphocyte homeostasis|T lymphocyte homeostasis				Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus.									biological_process											owl:Class	
GO:0002797	biolink:NamedThing	regulation of antibacterial peptide secretion	Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0001406	biolink:NamedThing	glycerophosphodiester transmembrane transporter activity	Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.	got7fsn_ti														molecular_function											owl:Class	
GO:0001407	biolink:NamedThing	glycerophosphodiester transmembrane transport	The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.	got7fsn_ti														biological_process											owl:Class	
GO:0002225	biolink:NamedThing	positive regulation of antimicrobial peptide production	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.	got7fsn_ti	stimulation of antimicrobial peptide production|upregulation of antimicrobial peptide production|up regulation of antimicrobial peptide production|antimicrobial peptide induction|activation of antimicrobial peptide production|up-regulation of antimicrobial peptide production													biological_process											owl:Class	
GO:0008582	biolink:NamedThing	regulation of synaptic assembly at neuromuscular junction	Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions.	got7fsn_ti	regulation of synaptic growth at neuromuscular junction													biological_process											owl:Class	
GO:0004533	biolink:NamedThing	exoribonuclease H activity	Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.	got7fsn_ti	retroviral reverse transcriptase RNaseH											MetaCyc:3.1.13.2-RXN|EC:3.1.13.2		molecular_function											owl:Class	
GO:1990317	biolink:NamedThing	Gin4 complex	A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved.	got7fsn_ti	Gin4-septin complex						bhm	2014-03-14T12:07:05Z						cellular_component											owl:Class	
GO:0000921	biolink:NamedThing	septin ring assembly	The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.	got7fsn_ti	septin assembly and septum biosynthesis|septin assembly and septum formation													biological_process											owl:Class	
GO:0031516	biolink:NamedThing	far-red light photoreceptor activity	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.	got7fsn_ti														molecular_function											owl:Class	
GO:0002572	biolink:NamedThing	pro-T cell differentiation	The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.	got7fsn_ti	pro-T lymphocyte differentiation													biological_process											owl:Class	
GO:0021881	biolink:NamedThing	Wnt-activated signaling pathway involved in forebrain neuron fate commitment	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain.	got7fsn_ti	Wnt receptor signaling pathway involved in forebrain neuron fate commitment|Wnt-activated signaling pathway involved in forebrain neuron fate commitment|Wnt receptor signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0099151	biolink:NamedThing	regulation of postsynaptic density assembly	Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.	got7fsn_ti							dos	2017-07-05T13:20:48Z						biological_process											owl:Class	
GO:0001655	biolink:NamedThing	urogenital system development	The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0016514	biolink:NamedThing	SWI/SNF complex	A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.	got7fsn_ti	SWI-SNF complex													cellular_component											owl:Class	
GO:0080181	biolink:NamedThing	lateral root branching	Any process involved in the formation of branches in lateral roots.	got7fsn_ti							dhl	2011-08-10T04:13:33Z						biological_process											owl:Class	
GO:0004455	biolink:NamedThing	ketol-acid reductoisomerase activity	Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.	got7fsn_ti	ketol acid reductoisomerase activity|dihydroxyisovalerate dehydrogenase (isomerizing) activity|acetohydroxy acid isomeroreductase activity|isomeroreductase activity|2-hydroxy-3-keto acid reductoisomerase activity|dihydroxyisovalerate (isomerizing) dehydrogenase activity|acetolactate reductoisomerase activity|reductoisomerase activity|alpha-keto-beta-hydroxylacyl reductoisomerase activity|(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)|acetohydroxy acid reductoisomerase activity											EC:1.1.1.86|MetaCyc:ACETOLACTREDUCTOISOM-RXN|RHEA:22068		molecular_function											owl:Class	
GO:0110113	biolink:NamedThing	positive regulation of lipid transporter activity	Any process that increases the frequency, rate, or extent of lipid transporter activity.	got7fsn_ti							kmv	2018-07-06T19:14:13Z						biological_process											owl:Class	
GO:0060769	biolink:NamedThing	positive regulation of epithelial cell proliferation involved in prostate gland development	Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.	got7fsn_ti							dph	2009-07-08T07:38:02Z						biological_process											owl:Class	
GO:0045275	biolink:NamedThing	respiratory chain complex III	A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.	got7fsn_ti	complex III|electron transport complex III|coenzyme Q-cytochrome c reductase complex|CoQH2-cytochrome c reductase complex|ubiquinol-cytochrome c oxidoreductase complex|ubiquinol-cytochrome-c reductase complex|cytochrome bc1 complex|coenzyme Q-cytochrome c oxidoreductase complex|cytochrome bc(1) complex										GO:0032842|GO:0045285	Wikipedia:Coenzyme_Q_-_cytochrome_c_reductase		cellular_component											owl:Class	
GO:0019452	biolink:NamedThing	L-cysteine catabolic process to taurine	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.	got7fsn_ti	L-cysteine breakdown to taurine|L-cysteine degradation to taurine													biological_process											owl:Class	
GO:0061285	biolink:NamedThing	mesonephric capsule development	The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.	got7fsn_ti							dph	2010-09-02T01:50:06Z						biological_process											owl:Class	
GO:1902797	biolink:NamedThing	negative regulation of snoRNA processing	Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing.	got7fsn_ti	down-regulation of snoRNA processing|inhibition of snoRNA processing|down regulation of snoRNA processing|downregulation of snoRNA processing						mah	2014-03-24T12:47:08Z						biological_process											owl:Class	
GO:0110110	biolink:NamedThing	positive regulation of animal organ morphogenesis	Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.	got7fsn_ti							kmv	2018-07-05T14:10:14Z						biological_process											owl:Class	
GO:0072191	biolink:NamedThing	ureter smooth muscle development	The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure.	got7fsn_ti							mah	2010-03-01T01:48:53Z						biological_process											owl:Class	
GO:0072264	biolink:NamedThing	metanephric glomerular endothelium development	The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.	got7fsn_ti							mah	2010-03-30T02:42:26Z						biological_process											owl:Class	
GO:0010707	biolink:NamedThing	globoside biosynthetic process via lactosylceramide	The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.	got7fsn_ti	lactosylceramide biosynthesis leading to globoside|globoside biosynthesis via lactosylceramide biosynthesis|biosynthesis of lactosylceramide precursor to globoside|lactosylceramide biosynthetic process leading to globoside													biological_process											owl:Class	
GO:2000078	biolink:NamedThing	positive regulation of type B pancreatic cell development	Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.	got7fsn_ti	positive regulation of pancreatic beta cell development|positive regulation of pancreatic B cell development						tb	2010-08-27T11:21:19Z						biological_process											owl:Class	
GO:0021554	biolink:NamedThing	optic nerve development	The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	got7fsn_ti	cranial nerve 2 development|CN II development|cranial nerve II development													biological_process											owl:Class	
CL:0000119	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046799	biolink:NamedThing	recruitment of helicase-primase complex to DNA lesions	The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair.	got7fsn_ti														biological_process											owl:Class	
GO:0060130	biolink:NamedThing	thyroid-stimulating hormone-secreting cell development	The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin.	got7fsn_ti	thyrotrope development|thyroid stimulating hormone secreting cell development|TSH-secreting cell development|beta-basophil development|thyrotroph development													biological_process											owl:Class	
GO:0002626	biolink:NamedThing	negative regulation of T cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.	got7fsn_ti	negative regulation of T-lymphocyte antigen processing and presentation|inhibition of T cell antigen processing and presentation|negative regulation of T lymphocyte antigen processing and presentation|downregulation of T cell antigen processing and presentation|down regulation of T cell antigen processing and presentation|down-regulation of T cell antigen processing and presentation|negative regulation of T-cell antigen processing and presentation													biological_process											owl:Class	
GO:0003163	biolink:NamedThing	sinoatrial node development	The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node.	got7fsn_ti	SAN development|sinus node development|SA node development						dph	2009-10-01T02:06:09Z						biological_process											owl:Class	
GO:0005577	biolink:NamedThing	fibrinogen complex	A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.	got7fsn_ti	fibrinogen beta chain|fibrinogen alpha chain|fibrinogen gamma chain|fibrinogen													cellular_component											owl:Class	
GO:0003292	biolink:NamedThing	cardiac septum cell differentiation	The process in which an endocardial cushion cell becomes a cell of a cardiac septum.	got7fsn_ti							dph	2009-10-20T11:03:46Z						biological_process											owl:Class	
GO:1904115	biolink:NamedThing	axon cytoplasm	Any cytoplasm that is part of a axon.	got7fsn_ti	axoplasm						sl	2015-04-06T18:13:14Z						cellular_component											owl:Class	
GO:0061168	biolink:NamedThing	regulation of hair follicle placode formation	Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.	got7fsn_ti							dph	2010-06-25T01:03:29Z						biological_process											owl:Class	
GO:0015252	biolink:NamedThing	proton channel activity	Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti	hydrogen ion channel activity													molecular_function											owl:Class	
GO:2000265	biolink:NamedThing	positive regulation of blood coagulation, extrinsic pathway	Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway.	got7fsn_ti							mah	2010-11-23T11:44:46Z						biological_process											owl:Class	
GO:0015438	biolink:NamedThing	ABC-type teichoic acid transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out).	got7fsn_ti	ABC-type teichoic-acid transporter|teichoic acid transmembrane transporter activity|ATPase-coupled teichoic acid transmembrane transporter activity|teichoic-acid-transporting ATPase activity|teichoic-acid ABC transporter|ATP-dependent teichoic acid transmembrane transporter activity										GO:0015162	EC:7.5.2.4|MetaCyc:3.6.3.40-RXN		molecular_function											owl:Class	
GO:0015777	biolink:NamedThing	teichoic acid transport	The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.	got7fsn_ti														biological_process											owl:Class	
GO:0000183	biolink:NamedThing	rDNA heterochromatin assembly	The assembly of chromatin characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of rDNA.	got7fsn_ti	chromatin silencing at ribosomal DNA|rDNA chromatin silencing|heterochromatic silencing at rDNA|chromatin silencing at rDNA	https://github.com/geneontology/go-ontology/issues/19238												biological_process											owl:Class	
GO:0060708	biolink:NamedThing	spongiotrophoblast differentiation	The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.	got7fsn_ti	spongiotrophoblast cell differentiation						dph	2009-06-09T10:38:10Z						biological_process											owl:Class	
GO:0001545	biolink:NamedThing	primary ovarian follicle growth	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle).	got7fsn_ti														biological_process											owl:Class	
GO:0048727	biolink:NamedThing	posterior cibarial plate development	The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:1903300	biolink:NamedThing	negative regulation of hexokinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity.	got7fsn_ti	down regulation of glucose ATP phosphotransferase activity|inhibition of hexokinase activity|down regulation of ATP-dependent hexokinase activity|inhibition of glucose ATP phosphotransferase activity|negative regulation of hexokinase type IV glucokinase activity|down-regulation of hexokinase type I activity|negative regulation of hexokinase (phosphorylating)|inhibition of hexokinase type IV|down regulation of hexokinase (phosphorylating)|negative regulation of hexokinase type I activity|down regulation of hexokinase D|down regulation of hexokinase activity|downregulation of hexokinase D|negative regulation of hexokinase type III activity|inhibition of hexokinase type IV glucokinase activity|inhibition of hexokinase type III activity|down-regulation of glucose ATP phosphotransferase activity|down regulation of hexokinase type IV (glucokinase) activity|down-regulation of hexokinase type III activity|down-regulation of hexokinase type IV glucokinase activity|negative regulation of hexokinase D|inhibition of hexokinase type IV (glucokinase) activity|down regulation of hexokinase type IV glucokinase activity|down-regulation of hexokinase type IV (glucokinase) activity|inhibition of hexokinase type I activity|negative regulation of hexokinase type II activity|downregulation of hexokinase type IV|down-regulation of hexokinase type IV|downregulation of hexokinase type IV glucokinase activity|downregulation of glucose ATP phosphotransferase activity|downregulation of hexokinase type III activity|inhibition of ATP-dependent hexokinase activity|down-regulation of hexokinase type II activity|downregulation of hexokinase activity|downregulation of hexokinase type II activity|inhibition of hexokinase (phosphorylating)|negative regulation of hexokinase type IV|downregulation of hexokinase type I activity|downregulation of ATP:D-hexose 6-phosphotransferase activity|negative regulation of hexokinase type IV (glucokinase) activity|negative regulation of ATP:D-hexose 6-phosphotransferase activity|down-regulation of hexokinase D|down-regulation of hexokinase (phosphorylating)|negative regulation of ATP-dependent hexokinase activity|downregulation of hexokinase type IV (glucokinase) activity|down regulation of hexokinase type I activity|down regulation of hexokinase type III activity|down regulation of hexokinase type II activity|downregulation of ATP-dependent hexokinase activity|down regulation of hexokinase type IV|down regulation of ATP:D-hexose 6-phosphotransferase activity|down-regulation of ATP:D-hexose 6-phosphotransferase activity|negative regulation of glucose ATP phosphotransferase activity|inhibition of ATP:D-hexose 6-phosphotransferase activity|down-regulation of hexokinase activity|down-regulation of ATP-dependent hexokinase activity|inhibition of hexokinase D|inhibition of hexokinase type II activity|downregulation of hexokinase (phosphorylating)						mr	2014-08-15T23:18:01Z						biological_process											owl:Class	
GO:0003165	biolink:NamedThing	Purkinje myocyte development	The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle.	got7fsn_ti	cardiac Purkinje fiber development						dph	2009-10-01T02:07:50Z						biological_process											owl:Class	
GO:0015218	biolink:NamedThing	pyrimidine nucleotide transmembrane transporter activity	Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0006864	biolink:NamedThing	pyrimidine nucleotide transport	The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0022018	biolink:NamedThing	lateral ganglionic eminence cell proliferation	The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0097281	biolink:NamedThing	immune complex formation	The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.	got7fsn_ti	antibody-mediated agglutination						pr	2012-03-26T01:35:21Z						biological_process											owl:Class	
GO:0007088	biolink:NamedThing	regulation of mitotic nuclear division	Any process that modulates the frequency, rate or extent of mitosis.	got7fsn_ti	regulation of mitosis													biological_process											owl:Class	
GO:0010884	biolink:NamedThing	positive regulation of lipid storage	Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.	got7fsn_ti	positive regulation of lipid sequestration													biological_process											owl:Class	
GO:1901698	biolink:NamedThing	response to nitrogen compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.	got7fsn_ti	response to nitrogen molecular entity						pr	2012-12-13T15:06:08Z						biological_process											owl:Class	
GO:0035078	biolink:NamedThing	induction of programmed cell death by ecdysone	Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.	got7fsn_ti														biological_process											owl:Class	
GO:0035075	biolink:NamedThing	response to ecdysone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0086089	biolink:NamedThing	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization						dph	2011-11-22T01:33:01Z						molecular_function											owl:Class	
GO:0003160	biolink:NamedThing	endocardium morphogenesis	The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	got7fsn_ti							dph	2009-10-01T01:37:26Z						biological_process											owl:Class	
GO:0021737	biolink:NamedThing	emboliform nucleus development	The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0015224	biolink:NamedThing	biopterin transmembrane transporter activity	Enables the transfer of biopterin from one side of a membrane to the other. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.	got7fsn_ti	biopterin transporter activity													molecular_function											owl:Class	
GO:0015877	biolink:NamedThing	biopterin transport	The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.	got7fsn_ti														biological_process											owl:Class	
GO:0048797	biolink:NamedThing	swim bladder formation	The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	got7fsn_ti	gas bladder formation|gas bladder biosynthesis													biological_process											owl:Class	
GO:0009998	biolink:NamedThing	negative regulation of retinal cone cell fate specification	Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell.	got7fsn_ti	down-regulation of retinal cone cell fate specification|negative regulation of retina cone cell fate specification|down regulation of retinal cone cell fate specification|suppression of retinal cone cell fate|downregulation of retinal cone cell fate specification|suppression of retina cone cell fate|inhibition of retinal cone cell fate specification													biological_process											owl:Class	
GO:0071953	biolink:NamedThing	elastic fiber	An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.	got7fsn_ti	elastin fiber|elastic fibre						mah	2010-10-11T11:44:57Z						cellular_component											owl:Class	
GO:0030450	biolink:NamedThing	regulation of complement activation, classical pathway	Any process that modulates the frequency, rate or extent of the classical pathway of complement activation.	got7fsn_ti	regulation of complement cascade, classical pathway													biological_process											owl:Class	
GO:2000043	biolink:NamedThing	regulation of cardiac cell fate specification	Any process that modulates the frequency, rate or extent of cardiac cell fate specification.	got7fsn_ti							tb	2010-08-19T09:01:04Z						biological_process											owl:Class	
GO:0015119	biolink:NamedThing	hexose phosphate transmembrane transporter activity	Enables the transfer of hexose phosphate from one side of a membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0015712	biolink:NamedThing	hexose phosphate transport	The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0035524	biolink:NamedThing	proline transmembrane transport	The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore.	got7fsn_ti	proline membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-05-04T04:52:46Z						biological_process											owl:Class	
GO:1990483	biolink:NamedThing	Clr6 histone deacetylase complex I''	A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3.	got7fsn_ti							al	2014-09-16T10:40:51Z						cellular_component											owl:Class	
GO:2000233	biolink:NamedThing	negative regulation of rRNA processing	Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.	got7fsn_ti	negative regulation of 35S primary transcript processing						mah	2010-11-10T12:11:33Z						biological_process											owl:Class	
GO:0106250	biolink:NamedThing	DNA-binding transcription repressor activity, RNA polymerase III-specific	A DNA-binding transcription factor activity that represses or decreases the transcription of specific genes sets transcribed by RNA polymerase III.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20253			For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		hjd	2020-02-19T19:34:18Z						molecular_function											owl:Class	
GO:0002364	biolink:NamedThing	NK T cell lineage commitment	The process in which a pro-T cell becomes committed to becoming an NK T cell.	got7fsn_ti	NK T-cell lineage commitment|natural killer T-cell lineage commitment|natural killer T lymphocyte lineage commitment|natural killer T-lymphocyte lineage commitment|NK T lymphocyte lineage commitment|NK T-lymphocyte lineage commitment													biological_process											owl:Class	
GO:0001865	biolink:NamedThing	NK T cell differentiation	The process in which a precursor cell type acquires the specialized features of a NK T cell.	got7fsn_ti	NK T lymphocyte differentiation|NKT cell differentiation|NK T cell development|natural T cell differentiation|natural killer T cell differentiation|NK T-lymphocyte differentiation|NT cell differentiation|NK T-cell differentiation				Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0038173	biolink:NamedThing	interleukin-17A-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-17A to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL17a signaling pathway|IL-17A-mediated signaling pathway|interleukin-17A signaling pathway|IL17A signaling pathway|interleukin-17A-mediated signalling pathway						bf	2012-06-12T10:59:01Z						biological_process											owl:Class	
GO:0062089	biolink:NamedThing	regulation of taurine biosynthetic process	Any process that modulates the rate, frequency or extent of taurine biosynthesis.	got7fsn_ti							dph	2018-11-07T14:05:44Z						biological_process											owl:Class	
GO:0071600	biolink:NamedThing	otic vesicle morphogenesis	The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.	got7fsn_ti							mah	2010-02-04T04:07:27Z						biological_process											owl:Class	
GO:1903681	biolink:NamedThing	regulation of epithelial cell-cell adhesion involved in epithelium migration	Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.	got7fsn_ti							als	2014-12-01T13:25:05Z						biological_process											owl:Class	
GO:1905376	biolink:NamedThing	negative regulation of cytochrome-c oxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity.	got7fsn_ti	downregulation of cytochrome a3 activity|negative regulation of cytochrome c oxidase activity|inhibition of cytochrome oxidase activity|negative regulation of complex IV (mitochondrial electron transport) activity|down regulation of indophenol oxidase|inhibition of ferrocytochrome-c:oxygen oxidoreductase|inhibition of NADH cytochrome c oxidase|inhibition of ferrocytochrome c oxidase|inhibition of ba3-type cytochrome c oxidase|down regulation of cbb3-type cytochrome c oxidase|negative regulation of ba3-type cytochrome c oxidase|downregulation of cytochrome c oxidase activity|down regulation of indophenolase|inhibition of indophenolase|down-regulation of indophenolase|down-regulation of cytochrome c oxidase activity|down-regulation of cytochrome-c oxidase activity|downregulation of cytochrome aa3 activity|downregulation of cytochrome-c oxidase activity|down regulation of ferrocytochrome c oxidase|down-regulation of indophenol oxidase|down regulation of cytochrome c oxidase activity|down-regulation of NADH cytochrome c oxidase|down regulation of warburg's respiratory enzyme activity|down-regulation of cytochrome aa3 activity|down-regulation of cytochrome oxidase activity|down regulation of cytochrome aa3 activity|down regulation of aa3-type cytochrome c oxidase|down regulation of ferrocytochrome-c:oxygen oxidoreductase|negative regulation of cytochrome aa3 activity|down-regulation of aa3-type cytochrome c oxidase|negative regulation of indophenolase|inhibition of aa3-type cytochrome c oxidase|down-regulation of complex IV (mitochondrial electron transport) activity|inhibition of cytochrome a3 activity|downregulation of indophenol oxidase|down-regulation of warburg's respiratory enzyme activity|down regulation of NADH cytochrome c oxidase|downregulation of indophenolase|downregulation of aa3-type cytochrome c oxidase|inhibition of cytochrome-c oxidase activity|negative regulation of ferrocytochrome-c:oxygen oxidoreductase|negative regulation of caa3-type cytochrome c oxidase|down-regulation of ferrocytochrome-c:oxygen oxidoreductase|negative regulation of indophenol oxidase|downregulation of caa3-type cytochrome c oxidase|downregulation of ferrocytochrome-c:oxygen oxidoreductase|down-regulation of ferrocytochrome c oxidase|down regulation of cytochrome-c oxidase activity|inhibition of indophenol oxidase|down-regulation of ba3-type cytochrome c oxidase|downregulation of cytochrome oxidase activity|downregulation of warburg's respiratory enzyme activity|down-regulation of cytochrome a3 activity|negative regulation of ferrocytochrome c oxidase|down regulation of complex IV (mitochondrial electron transport) activity|negative regulation of cytochrome oxidase activity|inhibition of cytochrome c oxidase activity|negative regulation of warburg's respiratory enzyme activity|negative regulation of aa3-type cytochrome c oxidase|negative regulation of cytochrome a3 activity|down-regulation of caa3-type cytochrome c oxidase|inhibition of cbb3-type cytochrome c oxidase|inhibition of warburg's respiratory enzyme activity|inhibition of complex IV (mitochondrial electron transport) activity|down-regulation of cbb3-type cytochrome c oxidase|down regulation of cytochrome oxidase activity|negative regulation of cbb3-type cytochrome c oxidase|down regulation of cytochrome a3 activity|downregulation of NADH cytochrome c oxidase|negative regulation of NADH cytochrome c oxidase|downregulation of ferrocytochrome c oxidase|downregulation of ba3-type cytochrome c oxidase|inhibition of caa3-type cytochrome c oxidase|downregulation of cbb3-type cytochrome c oxidase|down regulation of caa3-type cytochrome c oxidase|down regulation of ba3-type cytochrome c oxidase|inhibition of cytochrome aa3 activity|downregulation of complex IV (mitochondrial electron transport) activity						sl	2016-08-17T20:29:57Z						biological_process											owl:Class	
GO:0032832	biolink:NamedThing	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.	got7fsn_ti	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0017076	biolink:NamedThing	purine nucleotide binding	Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0051191	biolink:NamedThing	prosthetic group biosynthetic process	The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.	got7fsn_ti	prosthetic group formation|prosthetic group biosynthesis|coenzyme and prosthetic group biosynthetic process|coenzyme and prosthetic group biosynthesis|prosthetic group anabolism|prosthetic group synthesis													biological_process											owl:Class	
GO:1900439	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.	got7fsn_ti	up-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|up regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|upregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|activation of filamentous growth of a population of unicellular organisms in response to chemical stimulus						di	2012-04-25T05:55:35Z						biological_process											owl:Class	
GO:2000787	biolink:NamedThing	regulation of venous endothelial cell fate commitment	Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment.	got7fsn_ti							bf	2011-06-24T01:26:12Z						biological_process											owl:Class	
GO:0001781	biolink:NamedThing	neutrophil apoptotic process	Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.	got7fsn_ti	neutrophil apoptosis|programmed cell death of neutrophils by apoptosis|neutrophil programmed cell death by apoptosis|programmed cell death, neutrophils|apoptosis of neutrophils													biological_process											owl:Class	
GO:1900864	biolink:NamedThing	mitochondrial RNA modification	Any RNA modification that takes place in mitochondrion.	got7fsn_ti	mitochondrial RNA editing						tb	2012-06-11T10:49:56Z						biological_process											owl:Class	
GO:0032118	biolink:NamedThing	horsetail-astral microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis.	got7fsn_ti	horsetail-astral microtubule organisation|horsetail-astral microtubule array organization|horsetail-astral microtubule organization and biogenesis													biological_process											owl:Class	
GO:0030062	biolink:NamedThing	mitochondrial tricarboxylic acid cycle enzyme complex	Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.	got7fsn_ti	TCA cycle enzyme complex													cellular_component											owl:Class	
GO:2001211	biolink:NamedThing	negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.	got7fsn_ti	negative regulation of isopentenyl diphosphate synthesis, mevalonate pathway|negative regulation of acetate-mevalonate pathway|negative regulation of isopentenyl diphosphate anabolism, mevalonate pathway|negative regulation of isopentenyl diphosphate formation, mevalonate pathway|negative regulation of Ac-MVA pathway						bf	2011-11-15T10:53:45Z						biological_process											owl:Class	
GO:0021540	biolink:NamedThing	corpus callosum morphogenesis	The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.	got7fsn_ti														biological_process											owl:Class	
GO:1902677	biolink:NamedThing	left caudal basal body	Any ciliary basal body that is part of a left caudal flagellum found in Giardia species (trophozoite stage).	got7fsn_ti	microtubule basal body of left caudal cilium|ciliary basal body of left caudal flagellum|cilial basal body of left caudal flagellum|cilium basal body of left caudal cilium|left caudal flagellum ciliary basal body|cilial basal body of left caudal cilium|ciliary basal body of left caudal cilium|microtubule basal body of left caudal flagellum|cilium basal body of left caudal flagellum				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T15:00:36Z						cellular_component											owl:Class	
GO:0061219	biolink:NamedThing	mesonephric mesenchyme development	The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.	got7fsn_ti							dph	2010-08-17T03:45:44Z						biological_process											owl:Class	
GO:0034634	biolink:NamedThing	glutathione transmembrane transporter activity	Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0034775	biolink:NamedThing	glutathione transmembrane transport	A process in which glutathione is transported across a membrane.	got7fsn_ti	transmembrane glutathione transport|glutathione membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:0044190	biolink:NamedThing	host cell mitochondrial envelope	The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space.	got7fsn_ti							jl	2009-10-15T04:12:55Z						cellular_component											owl:Class	
GO:0021597	biolink:NamedThing	central nervous system structural organization	The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	got7fsn_ti	central nervous system structural organisation													biological_process											owl:Class	
GO:0021551	biolink:NamedThing	central nervous system morphogenesis	The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	got7fsn_ti														biological_process											owl:Class	
GO:0005896	biolink:NamedThing	interleukin-6 receptor complex	A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130.	got7fsn_ti	IL-6 receptor complex													cellular_component											owl:Class	
CL:0000746	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033029	biolink:NamedThing	regulation of neutrophil apoptotic process	Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.	got7fsn_ti	regulation of neutrophil apoptosis													biological_process											owl:Class	
GO:0090428	biolink:NamedThing	perianth development	The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals.	got7fsn_ti							tb	2012-05-08T06:02:15Z						biological_process											owl:Class	
GO:1905423	biolink:NamedThing	positive regulation of plant organ morphogenesis	Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis.	got7fsn_ti	upregulation of plant organ morphogenesis|activation of plant organ morphogenesis|up-regulation of plant organ morphogenesis|up regulation of plant organ morphogenesis						tb	2016-09-06T23:00:29Z						biological_process											owl:Class	
GO:0120317	biolink:NamedThing	sperm mitochondrial sheath assembly	The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.	got7fsn_ti							krc	2021-04-29T01:52:38Z						biological_process											owl:Class	
CL:0000847	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071690	biolink:NamedThing	cardiac muscle myosin thick filament assembly	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle.	got7fsn_ti							mah	2010-02-25T03:55:44Z						biological_process											owl:Class	
GO:0042813	biolink:NamedThing	Wnt-activated receptor activity	Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti	frizzled receptor activity|Wnt receptor activity|frizzled-2 receptor activity													molecular_function											owl:Class	
GO:1904823	biolink:NamedThing	purine nucleobase transmembrane transport	The process in which a purine nucleobase is transported across a membrane.	got7fsn_ti							vw	2015-11-19T09:07:56Z						biological_process											owl:Class	
GO:0009573	biolink:NamedThing	chloroplast ribulose bisphosphate carboxylase complex	A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. An example of this component is found in Arabidopsis thaliana.	got7fsn_ti	chloroplast RubisCO complex													cellular_component											owl:Class	
GO:0032043	biolink:NamedThing	mitochondrial DNA catabolic process	The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.	got7fsn_ti	mitochondrial DNA degradation|mtDNA breakdown|mitochondrial DNA catabolism|mtDNA catabolism|mitochondrial DNA breakdown|mtDNA degradation|mtDNA catabolic process													biological_process											owl:Class	
GO:1905822	biolink:NamedThing	regulation of mitotic sister chromatid arm separation	Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation.	got7fsn_ti							als	2017-01-16T13:36:29Z						biological_process											owl:Class	
GO:0072598	biolink:NamedThing	protein localization to chloroplast	A process in which a protein is transported to, or maintained at, a location in a chloroplast.	got7fsn_ti	protein localisation to chloroplast						mah	2011-02-14T02:20:30Z						biological_process											owl:Class	
GO:0097740	biolink:NamedThing	paraflagellar rod	A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signalling and metabolism, and in calcium signalling.	got7fsn_ti	PFR						pr	2016-10-19T11:30:08Z						cellular_component											owl:Class	
GO:0043865	biolink:NamedThing	methionine transmembrane transporter activity	Enables the transfer of methionine from one side of a membrane to the other.	got7fsn_ti	methionine importer activity|methionine-importing activity|methionine importing activity|methionine importer						pr	2013-11-15T10:35:04Z			GO:1990240			molecular_function											owl:Class	
GO:0015821	biolink:NamedThing	methionine transport	The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-methionine transport													biological_process											owl:Class	
GO:0002943	biolink:NamedThing	tRNA dihydrouridine synthesis	The process whereby a uridine in a transfer RNA is converted to dihydrouridine.	got7fsn_ti					Dihydrouridine is found in numerous positions within loop I, the so-called dihydrouridine loop, of many transfer RNAs. Most often found at positions 16 and 17, but also sometimes at positions 20, 20a, and 20b.		hjd	2012-11-16T16:20:37Z						biological_process											owl:Class	
GO:0099042	biolink:NamedThing	nucleation of clathrin-coated pit	The first step in clathrin-dependent endocytosis: invagination of the plasma membrane to form a pit.	got7fsn_ti														biological_process											owl:Class	
GO:0005384	biolink:NamedThing	manganese ion transmembrane transporter activity	Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-8959798|RHEA:28699		molecular_function											owl:Class	
GO:0045960	biolink:NamedThing	positive regulation of complement activation, classical pathway	Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.	got7fsn_ti	activation of complement activation, classical pathway|positive regulation of complement cascade, classical pathway|stimulation of complement activation, classical pathway|upregulation of complement activation, classical pathway|up regulation of complement activation, classical pathway|up-regulation of complement activation, classical pathway													biological_process											owl:Class	
GO:1903948	biolink:NamedThing	negative regulation of atrial cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential.	got7fsn_ti	downregulation of atrial cardiac muscle cell action potential|down-regulation of atrial cardiac muscle cell action potential|down regulation of atrial cardiac muscle cell action potential|inhibition of atrial cardiac muscle cell action potential						nc	2015-02-20T14:36:33Z						biological_process											owl:Class	
GO:0001054	biolink:NamedThing	RNA polymerase I activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase I promoter						krc	2010-09-23T03:36:11Z						molecular_function											owl:Class	
GO:0015498	biolink:NamedThing	pantothenate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0098719	biolink:NamedThing	sodium ion import across plasma membrane	The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	sodium ion import into cell|sodium import|sodium ion import						pr	2012-08-03T16:55:52Z			GO:1990118|GO:0097369			biological_process											owl:Class	
GO:0032834	biolink:NamedThing	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.	got7fsn_ti	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0106135	biolink:NamedThing	negative regulation of cardiac muscle cell contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction.	got7fsn_ti							hjd	2018-07-26T16:10:17Z						biological_process											owl:Class	
GO:0035289	biolink:NamedThing	posterior head segmentation	Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.	got7fsn_ti	gnathal segmentation				See also the fly_anatomy.ontology term 'gnathal segment ; FBbt:00000011' and its children.									biological_process											owl:Class	
GO:0005950	biolink:NamedThing	anthranilate synthase complex	A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine.	got7fsn_ti														cellular_component											owl:Class	
GO:1903295	biolink:NamedThing	negative regulation of glutamate secretion, neurotransmission	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission.	got7fsn_ti	down regulation of glutamate secretion, neurotransmission|down-regulation of glutamate secretion, neurotransmission|downregulation of glutamate secretion, neurotransmission|inhibition of glutamate secretion, neurotransmission				An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype		pad	2014-08-13T13:54:23Z						biological_process											owl:Class	
GO:1990411	biolink:NamedThing	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)	Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium.	got7fsn_ti							mah	2014-07-02T15:45:43Z				MetaCyc:RXN-14428|RHEA:42688		molecular_function											owl:Class	
GO:1903028	biolink:NamedThing	positive regulation of opsonization	Any process that activates or increases the frequency, rate or extent of opsonization.	got7fsn_ti	up-regulation of opsonization|upregulation of opsonization|activation of opsonization|up regulation of opsonization						rl	2014-05-16T17:34:54Z						biological_process											owl:Class	
GO:0046667	biolink:NamedThing	compound eye retinal cell programmed cell death	Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.	got7fsn_ti														biological_process											owl:Class	
GO:1901683	biolink:NamedThing	arsenate ion transmembrane transporter activity	Enables the transfer of an arsenate ion from one side of a membrane to the other.	got7fsn_ti							tb	2012-12-04T23:26:27Z						molecular_function											owl:Class	
GO:1901684	biolink:NamedThing	arsenate ion transmembrane transport	The process in which arsenate is transported across a membrane.	got7fsn_ti					Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2012-12-04T23:26:36Z						biological_process											owl:Class	
GO:0005548	biolink:NamedThing	phospholipid transporter activity	Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.	got7fsn_ti											GO:0008497	Reactome:R-HSA-8865637|Reactome:R-HSA-216757|Reactome:R-HSA-5678749|Reactome:R-HSA-382553|Reactome:R-HSA-8867876|Reactome:R-HSA-8857662|Reactome:R-HSA-5678706		molecular_function											owl:Class	
GO:0015914	biolink:NamedThing	phospholipid transport	The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.	got7fsn_ti														biological_process											owl:Class	
GO:0031422	biolink:NamedThing	RecQ family helicase-topoisomerase III complex	A complex containing a RecQ family helicase and a topoisomerase III homologue (a member of the topoisomerase type IA subfamily); may also include one or more additional proteins; conserved from E. coli to human.	got7fsn_ti	RecQ helicase-Topo III complex|Sgs1-Top3 complex													cellular_component											owl:Class	
GO:0090602	biolink:NamedThing	sieve element enucleation	The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded.	got7fsn_ti							tb	2014-09-05T16:25:16Z						biological_process											owl:Class	
GO:0090603	biolink:NamedThing	sieve element differentiation	The process whereby a relatively unspecialized cell acquires specialized features of a sieve element.	got7fsn_ti							tb	2014-09-05T16:38:20Z						biological_process											owl:Class	
GO:0021946	biolink:NamedThing	deep nuclear neuron cell migration	The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei.	got7fsn_ti														biological_process											owl:Class	
GO:0045854	biolink:NamedThing	positive regulation of bicoid mRNA localization	Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.	got7fsn_ti	activation of bicoid mRNA localization|positive regulation of bicoid mRNA localisation|up-regulation of bicoid mRNA localization|upregulation of bicoid mRNA localization|up regulation of bicoid mRNA localization|stimulation of bicoid mRNA localization													biological_process											owl:Class	
GO:0015410	biolink:NamedThing	ABC-type manganese transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in).	got7fsn_ti	ABC-type Mn(2+) transporter|manganese transmembrane transporter activity, phosphorylative mechanism|manganese-transporting ATPase activity|manganese ABC transporter|ATPase-coupled manganese transmembrane transporter activity|ATP-dependent manganese transmembrane transporter activity											Reactome:R-HSA-5692462|MetaCyc:3.6.3.35-RXN|RHEA:17365|EC:7.2.2.5		molecular_function											owl:Class	
GO:0005547	biolink:NamedThing	phosphatidylinositol-3,4,5-trisphosphate binding	Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.	got7fsn_ti	PIP3 binding													molecular_function											owl:Class	
GO:0048923	biolink:NamedThing	posterior lateral line neuromast hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0003842	biolink:NamedThing	1-pyrroline-5-carboxylate dehydrogenase activity	Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H(+).	got7fsn_ti	1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity|L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity|pyrroline-5-carboxylic acid dehydrogenase activity|pyrroline-5-carboxylate dehydrogenase activity|1-pyrroline dehydrogenase|delta1-pyrroline-5-carboxylate dehydrogenase activity											Reactome:R-HSA-70679|EC:1.2.1.88|MetaCyc:PYRROLINECARBDEHYDROG-RXN|Reactome:R-HSA-6784399|RHEA:16417		molecular_function											owl:Class	
GO:0008179	biolink:NamedThing	adenylate cyclase binding	Binding to an adenylate cyclase.	got7fsn_ti	adenylyl cyclase binding											Reactome:R-HSA-170672		molecular_function											owl:Class	
GO:0047872	biolink:NamedThing	dolichol O-acyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate.	got7fsn_ti	acyl-CoA:dolichol acyltransferase activity|palmitoyl-CoA:dolichol O-palmitoyltransferase activity											EC:2.3.1.123|RHEA:16685|MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0120146	biolink:NamedThing	sulfatide binding	Binding to sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group.	got7fsn_ti	sulfated galactocerebroside binding|3-O-sulfogalactosylceramide binding|SM4 binding						krc	2018-03-30T20:44:03Z						molecular_function											owl:Class	
GO:0051861	biolink:NamedThing	glycolipid binding	Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0044528	biolink:NamedThing	regulation of mitochondrial mRNA stability	Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs.	got7fsn_ti							jl	2012-03-15T03:20:10Z						biological_process											owl:Class	
GO:0098790	biolink:NamedThing	ncRNA transcription associated with protein coding gene TSS/TES	The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes.	got7fsn_ti	pasRNA transcription													biological_process											owl:Class	
GO:0098781	biolink:NamedThing	ncRNA transcription	The transcription of non (protein) coding RNA from a DNA template.	got7fsn_ti														biological_process											owl:Class	
GO:0018637	biolink:NamedThing	1-hydroxy-2-naphthoate hydroxylase activity	Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene.	got7fsn_ti												EC:1.14.13.-|UM-BBD_reactionID:r0491		molecular_function											owl:Class	
GO:0042778	biolink:NamedThing	tRNA end turnover	The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0071459	biolink:NamedThing	protein localization to chromosome, centromeric region	Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.	got7fsn_ti	protein localization to centromere|protein localisation to chromosome, centromeric region|protein localization to chromosome, centric region						mah	2009-12-17T02:11:23Z						biological_process											owl:Class	
GO:0016166	biolink:NamedThing	phytoene dehydrogenase activity	Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.	got7fsn_ti														molecular_function											owl:Class	
GO:0051118	biolink:NamedThing	glucan endo-1,3-alpha-glucosidase activity	Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.	got7fsn_ti	mutanase activity|1,3(1,3;1,4)-alpha-D-glucan 3-glucanohydrolase activity|endo-1,3-alpha-glucanase activity|endo-1,3-alpha-D-glucanase activity|endo-(1->3)-alpha-glucanase activity|cariogenase activity|cariogenanase activity											MetaCyc:3.2.1.59-RXN|EC:3.2.1.59		molecular_function											owl:Class	
GO:0098836	biolink:NamedThing	cytoskeleton of dendritic spine	The portion of the cytoskeleton that lies within a dendritic spine.  The actin component of this cytoskeleton is involved in spine head remodelling in response to postsynaptic signalling.	got7fsn_ti														cellular_component											owl:Class	
GO:0017181	biolink:NamedThing	peptidyl-diphthine catabolic process	The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue.	got7fsn_ti	peptidyl-diphthine degradation|peptidyl-diphthine catabolism|peptidyl-diphthine breakdown													biological_process											owl:Class	
GO:0009301	biolink:NamedThing	snRNA transcription	The synthesis of small nuclear RNA (snRNA) from a DNA template.	got7fsn_ti														biological_process											owl:Class	
GO:0018095	biolink:NamedThing	protein polyglutamylation	The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.	got7fsn_ti												RESID:AA0202		biological_process											owl:Class	
GO:0018493	biolink:NamedThing	formylmethanofuran dehydrogenase activity	Catalysis of the reaction: N-formylmethanofuran + A + H(2)O + H(+) = AH(2) + CO(2) + methanofuran.	got7fsn_ti	formylmethanofuran:(acceptor) oxidoreductase activity|formylmethanofuran:acceptor oxidoreductase activity											MetaCyc:FORMYLMETHANOFURAN-DEHYDROGENASE-RXN|RHEA:19841|EC:1.2.7.12|KEGG_REACTION:R03015|UM-BBD_reactionID:r0345		molecular_function											owl:Class	
GO:0002638	biolink:NamedThing	negative regulation of immunoglobulin production	Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.	got7fsn_ti	downregulation of immunoglobulin production|negative regulation of immunoglobulin biosynthetic process|negative regulation of immunoglobulin secretion|inhibition of immunoglobulin production|down regulation of immunoglobulin production|down-regulation of immunoglobulin production										GO:0002641|GO:0051025			biological_process											owl:Class	
GO:0051746	biolink:NamedThing	thalianol synthase activity	Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol).	got7fsn_ti												EC:5.4.99.31|RHEA:26160		molecular_function											owl:Class	
GO:0102885	biolink:NamedThing	alpha-cuprenene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (-)-alpha-cuprenene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8426|RHEA:32027|EC:4.2.3.95		molecular_function											owl:Class	
GO:0030342	biolink:NamedThing	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).	got7fsn_ti	calcitriol 24-hydroxylase activity|1,25-(OH)2D3 24-hydroxylase activity											Reactome:R-HSA-211950|Reactome:R-HSA-209765|Reactome:R-HSA-5602004		molecular_function											owl:Class	
GO:0071605	biolink:NamedThing	monocyte chemotactic protein-1 production	The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CCL2 production|MCP-1 production						mah	2010-02-05T04:09:53Z						biological_process											owl:Class	
GO:0050068	biolink:NamedThing	lysine carbamoyltransferase activity	Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H(+) + phosphate.	got7fsn_ti	lysine transcarbamylase activity|carbamoyl-phosphate:L-lysine carbamoyltransferase activity											MetaCyc:LYSINE-CARBAMOYLTRANSFERASE-RXN|EC:2.1.3.8|RHEA:17121|KEGG_REACTION:R01396		molecular_function											owl:Class	
GO:0055097	biolink:NamedThing	high density lipoprotein particle mediated signaling	A series of molecular signals mediated by the detection of high density lipoprotein particle.	got7fsn_ti	high density lipoprotein mediated signalling|high density lipoprotein particle-mediated signaling|high density lipoprotein particle mediated signal transduction													biological_process											owl:Class	
GO:0002235	biolink:NamedThing	detection of unfolded protein	The series of events in which an unfolded protein stimulus is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0004361	biolink:NamedThing	glutaryl-CoA dehydrogenase activity	Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor.	got7fsn_ti	glutaryl coenzyme A dehydrogenase activity|glutaryl-CoA:acceptor 2,3-oxidoreductase (decarboxylating)|glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating)											RHEA:13389|EC:1.3.8.6|MetaCyc:GLUTARYL-COA-DEHYDROGENASE-RXN|UM-BBD_reactionID:r0198|Reactome:R-HSA-71046		molecular_function											owl:Class	
GO:0071942	biolink:NamedThing	XPC complex	A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2.	got7fsn_ti							mah	2010-10-01T11:09:36Z						cellular_component											owl:Class	
GO:0140474	biolink:NamedThing	mitochondrion-endoplasmic reticulum membrane tether activity	The binding activity of a molecule that brings together a mitochondrion and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.	got7fsn_ti	endoplasmic reticulum-mitochondrion membrane tether activity|mitochondrion-ER membrane adaptor activity|mitochondrion-endoplasmic reticulum membrane adaptor activity|mitochondrion-ER membrane tether activity|ER-mitochondrion membrane tether activity|endoplasmic reticulum-mitochondrion membrane adaptor activity|ER-mitochondrion membrane adaptor activity	https://github.com/geneontology/go-ontology/issues/19634					pg	2020-06-22T07:01:14Z						molecular_function											owl:Class	
GO:0010771	biolink:NamedThing	negative regulation of cell morphogenesis involved in differentiation	Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	got7fsn_ti														biological_process											owl:Class	
GO:0033946	biolink:NamedThing	xyloglucan-specific endo-beta-1,4-glucanase activity	Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.	got7fsn_ti	xyloglucan endo-beta-1,4-glucanase activity|[(1->6)-beta-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase activity|xyloglucanendohydrolase activity|XH|XEG|xyloglucanase activity|1,4-beta-D-glucan glucanohydrolase activity											MetaCyc:3.2.1.151-RXN|EC:3.2.1.151		molecular_function											owl:Class	
GO:0030379	biolink:NamedThing	neurotensin receptor activity, non-G protein-coupled	Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.	got7fsn_ti	neurotensin receptor activity, non G protein coupled|non G protein coupled neurotensin receptor activity|non-G-protein coupled neurotensin receptor activity|non-G-protein-coupled neurotensin receptor activity|neurotensin receptor activity, non-G-protein coupled													molecular_function											owl:Class	
GO:0034298	biolink:NamedThing	arthrospore formation	The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.	got7fsn_ti	arthroconidium formation													biological_process											owl:Class	
GO:0046941	biolink:NamedThing	azetidine-2-carboxylic acid acetyltransferase activity	Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0036145	biolink:NamedThing	dendritic cell homeostasis	The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti	DC homeostasis						bf	2012-03-12T11:05:36Z						biological_process											owl:Class	
GO:0010428	biolink:NamedThing	methyl-CpNpG binding	Binding to a methylated cytosine/unspecified/guanine trinucleotide.	got7fsn_ti														molecular_function											owl:Class	
GO:0038046	biolink:NamedThing	G protein-coupled enkephalin receptor activity	Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body.	got7fsn_ti	enkephalin receptor activity|delta-opioid receptor activity	https://github.com/geneontology/go-ontology/issues/21110					bf	2011-11-14T01:30:14Z						molecular_function											owl:Class	
GO:0070942	biolink:NamedThing	neutrophil mediated cytotoxicity	The directed killing of a target cell by a neutrophil.	got7fsn_ti	neutrophil mediated cell killing						mah	2009-10-01T01:49:30Z						biological_process											owl:Class	
GO:0032221	biolink:NamedThing	Rpd3S/Clr6-CII complex	A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).	got7fsn_ti	Rpd3C(S)|Clr6-CII|Clr6 histone deacetylase complex II'|Clr6 histone deacetylase complex II|Rpd3S complex|Clr6S complex	https://github.com/geneontology/go-ontology/issues/19819									GO:0000509			cellular_component											owl:Class	
GO:0046507	biolink:NamedThing	UDPsulfoquinovose synthase activity	Catalysis of the reaction: sulfite + UDP-D-glucose = H(2)O + UDP-6-sulfoquinovose.	got7fsn_ti	UDPsulphoquinovose synthase activity|UDP-6-sulfo-6-deoxyglucose sulfohydrolase activity|UDP-sulfoquinovose synthase activity|sulfite:UDP-glucose sulfotransferase activity											KEGG_REACTION:R05775|RHEA:13197|EC:3.13.1.1|MetaCyc:RXN-1223		molecular_function											owl:Class	
GO:0140082	biolink:NamedThing	SUMO-ubiquitin ligase activity	Isoenergetic transfer of SUMO from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.	got7fsn_ti							pg	2017-08-08T14:46:50Z						molecular_function											owl:Class	
GO:0035617	biolink:NamedThing	stress granule disassembly	The disaggregation of a stress granule into its constituent protein and RNA parts.	got7fsn_ti	SG disassembly						bf	2010-12-03T10:38:57Z						biological_process											owl:Class	
GO:0004796	biolink:NamedThing	thromboxane-A synthase activity	Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).	got7fsn_ti	(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity|thromboxane synthetase activity|cytochrome P450 CYP5|thromboxane synthase activity										GO:0008400	EC:5.3.99.5|Reactome:R-HSA-5603275|RHEA:17137|MetaCyc:THROMBOXANE-A-SYNTHASE-RXN|KEGG_REACTION:R02268|Reactome:R-HSA-76500		molecular_function											owl:Class	
GO:0021632	biolink:NamedThing	optic nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	got7fsn_ti	CN II maturation													biological_process											owl:Class	
GO:0102281	biolink:NamedThing	formylaminopyrimidine deformylase activity	Catalysis of the reaction: formylaminopyrimidine + H2O <=> 4-amino-5-ammoniomethyl-2-methylpyrimidine + formate.	got7fsn_ti												MetaCyc:RXN-12612		molecular_function											owl:Class	
GO:0044288	biolink:NamedThing	puncta adhaerentia	A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells.	got7fsn_ti							jl	2010-02-04T02:19:38Z				NIF_Subcellular:sao257629430		cellular_component											owl:Class	
GO:0009731	biolink:NamedThing	detection of sucrose stimulus	The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of sucrose stimulus													biological_process											owl:Class	
GO:0009744	biolink:NamedThing	response to sucrose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.	got7fsn_ti	response to sucrose stimulus													biological_process											owl:Class	
GO:0102252	biolink:NamedThing	cellulose 1,4-beta-cellobiosidase activity (reducing end)	Catalysis of the reaction: n H2O + a cellodextrin = n beta-cellobiose, releasing cellobiose from the reducing ends of the chains.	got7fsn_ti												EC:3.2.1.176|MetaCyc:RXN-12420		molecular_function											owl:Class	
GO:1990752	biolink:NamedThing	microtubule end	Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end.	got7fsn_ti					This term should be used when it is not possible to distinguish between the two microtubule ends, e.g. during image annotation. Whenever possible, please annotate to one of the more specific children GO:0035371 'microtubule plus-end' or GO:0036449 'microtubule minus-end'.		pr	2015-05-25T12:50:31Z						cellular_component											owl:Class	
GO:0016034	biolink:NamedThing	maleylacetoacetate isomerase activity	Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate.	got7fsn_ti	maleylacetone cis-trans-isomerase activity|maleylacetoacetic isomerase activity|4-maleylacetoacetate cis-trans-isomerase activity|maleylacetone isomerase activity										GO:0018841	RHEA:14817|UM-BBD_reactionID:r0106|MetaCyc:MALEYLACETOACETATE-ISOMERASE-RXN|Reactome:R-HSA-71173|EC:5.2.1.2		molecular_function											owl:Class	
GO:1904784	biolink:NamedThing	NLRP1 inflammasome complex assembly	The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex.	got7fsn_ti	NALP1 inflammasome complex formation|NLRP1 inflammasome complex formation|NALP1 inflammasome complex assembly	https://github.com/geneontology/go-ontology/issues/21092			The aggregation, arrangement and bonding together of a set of components to form the NLRP1 inflammasome complex, occurring at the level of an individual cell.		ae	2015-11-02T09:39:44Z						biological_process											owl:Class	
GO:0017023	biolink:NamedThing	myosin phosphatase complex	An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin.	got7fsn_ti														cellular_component											owl:Class	
GO:0008783	biolink:NamedThing	agmatinase activity	Catalysis of the reaction: agmatine + H(2)O = putrescine + urea.	got7fsn_ti	agmatine ureohydrolase activity|agmatine amidinohydrolase|SpeB											KEGG_REACTION:R01157|EC:3.5.3.11|MetaCyc:AGMATIN-RXN|Reactome:R-HSA-350604|RHEA:13929		molecular_function											owl:Class	
GO:0047734	biolink:NamedThing	CDP-glycerol diphosphatase activity	Catalysis of the reaction: CDP-glycerol + H(2)O = sn-glycerol 3-phosphate + CMP + 2 H(+).	got7fsn_ti	CDPglycerol diphosphatase activity|CDPglycerol phosphoglycerohydrolase activity|CDP-glycerol pyrophosphatase activity|cytidine diphosphoglycerol pyrophosphatase activity|CDPglycerol pyrophosphatase activity|CDP-glycerol phosphoglycerohydrolase activity											EC:3.6.1.16|MetaCyc:CDP-GLYCEROL-PYROPHOSPHATASE-RXN|KEGG_REACTION:R00855|RHEA:21692		molecular_function											owl:Class	
GO:0016362	biolink:NamedThing	activin receptor activity, type II	Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.	got7fsn_ti	type II activin receptor activity											Reactome:R-HSA-201443		molecular_function											owl:Class	
GO:0106243	biolink:NamedThing	syn-isopimara-7,15-diene synthase activity	Catalysis of the reaction: 9alpha-copalyl diphosphate = diphosphate + syn-isopimara-7,15-diene.	got7fsn_ti							hjd	2019-12-19T19:04:32Z				RHEA:62188		molecular_function											owl:Class	
GO:0061775	biolink:NamedThing	cohesin loading activity	Facilitating a conformational change to load a cohesin complex around sister chromatids, driven by ATP hydrolysis.	got7fsn_ti	cohesin loading ATPase|cohesin ATPase activity|ATP-dependent cohesin loading activity	https://github.com/geneontology/go-ontology/issues/14205|https://github.com/geneontology/go-ontology/issues/21700					dph	2016-07-13T12:54:43Z						molecular_function											owl:Class	
GO:0014707	biolink:NamedThing	branchiomeric skeletal muscle development	The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.	got7fsn_ti														biological_process											owl:Class	
GO:0102146	biolink:NamedThing	tricetin O-methytransferase activity	Catalysis of the reaction: tricetin + S-adenosyl-L-methionine  = H+ + 3'-O-methyltricetin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-11582|RHEA:27493		molecular_function											owl:Class	
GO:0001602	biolink:NamedThing	pancreatic polypeptide receptor activity	Combining with pancreatic polypeptide PP to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0004983	biolink:NamedThing	neuropeptide Y receptor activity	Combining with neuropeptide Y to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0098863	biolink:NamedThing	nuclear migration by microtubule mediated pushing forces	The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules.	got7fsn_ti														biological_process											owl:Class	
GO:0099098	biolink:NamedThing	microtubule polymerization based movement	The movement of a cellular component as a result of microtubule polymerization.	got7fsn_ti														biological_process											owl:Class	
GO:0102944	biolink:NamedThing	medicagenate UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate <=> UDP(3-) + a medicagenate monoglucoside.	got7fsn_ti												MetaCyc:RXN-9035		molecular_function											owl:Class	
GO:0150090	biolink:NamedThing	multiple spine synapse organization, single dendrite	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite.	got7fsn_ti							bc	2018-08-08T14:59:49Z						biological_process											owl:Class	
GO:1900555	biolink:NamedThing	emericellamide metabolic process	The chemical reactions and pathways involving emericellamide.	got7fsn_ti	emericellamide metabolism						di	2012-05-15T01:32:19Z						biological_process											owl:Class	
GO:1990062	biolink:NamedThing	RPAP3/R2TP/prefoldin-like complex	A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity.	got7fsn_ti	R2TP/prefoldin-like complex						pr	2013-03-20T15:31:12Z						cellular_component											owl:Class	
GO:0097318	biolink:NamedThing	invasive growth in response to abiotic stimulus	The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans.	got7fsn_ti							pr	2012-05-31T10:39:31Z						biological_process											owl:Class	
GO:0047102	biolink:NamedThing	aminomuconate-semialdehyde dehydrogenase activity	Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate.	got7fsn_ti	2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase activity|alpha-aminomuconic epsilon-semialdehyde dehydrogenase activity|2-hydroxymuconate semialdehyde dehydrogenase activity|2-hydroxymuconic acid semialdehyde dehydrogenase activity|alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase activity|2-hydroxymuconic semialdehyde dehydrogenase activity|2-aminomuconate semialdehyde dehydrogenase activity											MetaCyc:1.2.1.32-RXN|Reactome:R-HSA-71239|EC:1.2.1.32|UM-BBD_reactionID:r1434|RHEA:14469		molecular_function											owl:Class	
GO:0008924	biolink:NamedThing	malate dehydrogenase (quinone) activity	Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol.	got7fsn_ti	(S)-malate:quinone oxidoreductase activity|FAD-dependent malate dehydrogenase activity|(S)-malate:(quinone) oxidoreductase activity|MQO activity											RHEA:22556|EC:1.1.5.4|MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN		molecular_function											owl:Class	
GO:0005131	biolink:NamedThing	growth hormone receptor binding	Binding to a growth hormone receptor.	got7fsn_ti	growth hormone receptor ligand|growth hormone													molecular_function											owl:Class	
GO:0018772	biolink:NamedThing	trioxoheptanoate hydrolase activity	Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate.	got7fsn_ti												MetaCyc:R306-RXN|UM-BBD_reactionID:r0094		molecular_function											owl:Class	
GO:0034711	biolink:NamedThing	inhibin binding	Binding to an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.	got7fsn_ti	inhibin beta-B binding|inhibin beta-A binding|inhibin alpha binding|inhibin monomer binding										GO:0034712|GO:0048186|GO:0048187			molecular_function											owl:Class	
GO:0044616	biolink:NamedThing	modulation of relaxation of muscle in other organism	The process in which an organism effects a change in the relaxation of muscle in a second organism.	got7fsn_ti	regulation of relaxation of muscle in other organism						jl	2012-07-04T01:54:12Z						biological_process											owl:Class	
GO:1901077	biolink:NamedThing	regulation of relaxation of muscle	Any process that modulates the frequency, rate or extent of relaxation of muscle.	got7fsn_ti							jl	2012-07-04T10:44:30Z						biological_process											owl:Class	
GO:0018975	biolink:NamedThing	anaerobic 2,4,6-trinitrotoluene metabolic process	The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen.	got7fsn_ti	anaerobic 2,4,6-trinitrotoluene metabolism											UM-BBD_pathwayID:tnt2		biological_process											owl:Class	
GO:0018974	biolink:NamedThing	2,4,6-trinitrotoluene metabolic process	The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.	got7fsn_ti	TNT metabolic process|2,4,6-trinitrotoluene metabolism|TNT metabolism													biological_process											owl:Class	
GO:0060646	biolink:NamedThing	internal mammary gland bud epithelial cell differentiation	The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.	got7fsn_ti							dph	2009-05-29T08:10:48Z						biological_process											owl:Class	
GO:0035611	biolink:NamedThing	protein branching point deglutamylation	The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue.	got7fsn_ti							bf	2010-11-18T01:11:21Z						biological_process											owl:Class	
GO:0051673	biolink:NamedThing	membrane disruption in other organism	The disruption of the membranes of another organism, leading to damage to its cells and possibly death of that organism.	got7fsn_ti	membrane disruption in another organism|cytolysis, by membrane disruption, in other organism													biological_process											owl:Class	
GO:0045107	biolink:NamedThing	intermediate filament polymerization	Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain.	got7fsn_ti														biological_process											owl:Class	
GO:0044194	biolink:NamedThing	cytolytic granule	A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells.	got7fsn_ti							jl	2009-10-20T01:22:13Z						cellular_component											owl:Class	
GO:0045243	biolink:NamedThing	cytosolic isocitrate dehydrogenase complex (NAD+)	Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity.	got7fsn_ti	isocitrate dehydrogenase complex (NAD+)													cellular_component											owl:Class	
GO:0018458	biolink:NamedThing	isopiperitenol dehydrogenase activity	Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD(+) = (6R)-isoperitenone + H(+) + NADH.	got7fsn_ti	(-)-trans-isopiperitenol:NAD+ oxidoreductase activity											RHEA:20860|EC:1.1.1.223|KEGG_REACTION:R03261|UM-BBD_reactionID:r0740|MetaCyc:ISOPIPERITENOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0046394	biolink:NamedThing	carboxylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.	got7fsn_ti	carboxylic acid biosynthesis|carboxylic acid formation|carboxylic acid anabolism|carboxylic acid synthesis													biological_process											owl:Class	
GO:0006422	biolink:NamedThing	aspartyl-tRNA aminoacylation	The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid  accetping tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0017146	biolink:NamedThing	NMDA selective glutamate receptor complex	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.	got7fsn_ti	NMDA-selective glutamate receptor|N-methyl-D-aspartate selective glutamate receptor complex													cellular_component											owl:Class	
GO:0008786	biolink:NamedThing	allose 6-phosphate isomerase activity	Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate.	got7fsn_ti												RHEA:28430|MetaCyc:RXN0-303		molecular_function											owl:Class	
GO:0016655	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.	got7fsn_ti	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor											EC:1.6.5.-		molecular_function											owl:Class	
GO:0061453	biolink:NamedThing	interstitial cell of Cajal differentiation	The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.	got7fsn_ti	ICC differentiation						dph	2012-07-20T08:20:50Z						biological_process											owl:Class	
GO:0009002	biolink:NamedThing	serine-type D-Ala-D-Ala carboxypeptidase activity	Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.	got7fsn_ti	D-alanyl-D-alanine-cleaving-peptidase activity|D-alanine carboxypeptidase|D-alanyl carboxypeptidase activity|DD-transpeptidase activity|D-alanyl-D-alanine-cleaving peptidase activity|DD-peptidase activity|DD-carboxypeptidase|D-alanyl-D-alanine-carboxypeptidase activity|D-alanyl-D-alanine carboxypeptidase activity											EC:3.4.16.4|MetaCyc:3.4.16.4-RXN		molecular_function											owl:Class	
GO:0005237	biolink:NamedThing	inhibitory extracellular ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels.	got7fsn_ti														molecular_function											owl:Class	
GO:0106357	biolink:NamedThing	glycerol-1-phosphate dehydrogenase [NAD+] activity	Catalysis of the reaction: NAD+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADH.	got7fsn_ti							hjd	2021-02-02T06:07:55Z				RHEA:21412		molecular_function											owl:Class	
GO:1990088	biolink:NamedThing	[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity	Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein].	got7fsn_ti							hjd	2013-05-06T15:07:20Z				EC:2.1.1.246|RHEA:45208		molecular_function											owl:Class	
GO:0061047	biolink:NamedThing	positive regulation of branching involved in lung morphogenesis	Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.	got7fsn_ti							dph	2010-02-25T10:50:01Z						biological_process											owl:Class	
GO:0048836	biolink:NamedThing	specification of increased petal number	Any process that increases the number of petals produced in a developing flower.	got7fsn_ti														biological_process											owl:Class	
GO:0016516	biolink:NamedThing	interleukin-4 receptor complex	A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor.	got7fsn_ti	IL-4 receptor complex													cellular_component											owl:Class	
GO:0035304	biolink:NamedThing	regulation of protein dephosphorylation	Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.	got7fsn_ti	regulation of protein amino acid dephosphorylation													biological_process											owl:Class	
GO:0102055	biolink:NamedThing	12-hydroxyjasmonate sulfotransferase activity	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + a 12-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + a 12-hydroxyjasmonate sulfate.	got7fsn_ti												EC:2.8.2.39|MetaCyc:RXN-10451|RHEA:52728		molecular_function											owl:Class	
GO:0018793	biolink:NamedThing	3,5-dibromo-4-hydroxybenzoate decarboxylase activity	Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol.	got7fsn_ti												UM-BBD_reactionID:r0546		molecular_function											owl:Class	
GO:0097466	biolink:NamedThing	ubiquitin-dependent glycoprotein ERAD pathway	An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.	got7fsn_ti	ER-associated glycoprotein degradation|glycoprotein ERAD|misfolded or incompletely synthesized glycoprotein catabolic process|gpERAD						pr	2013-02-05T16:37:13Z						biological_process											owl:Class	
GO:0002348	biolink:NamedThing	central B cell positive selection	Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.	got7fsn_ti	central B-cell positive selection|central B lymphocyte positive selection|central B-lymphocyte positive selection													biological_process											owl:Class	
GO:0046967	biolink:NamedThing	cytosol to endoplasmic reticulum transport	The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.	got7fsn_ti	cytosol to endoplasmic reticulum transport|cytosol to ER transport													biological_process											owl:Class	
GO:0010479	biolink:NamedThing	stele development	The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds.	got7fsn_ti														biological_process											owl:Class	
GO:0070712	biolink:NamedThing	RNA cytidine-uridine insertion	The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide.	got7fsn_ti	RNA CU insertion						mah	2009-06-08T05:27:01Z						biological_process											owl:Class	
GO:0070367	biolink:NamedThing	negative regulation of hepatocyte differentiation	Any process that stops or decreases the rate or extent of hepatocyte differentiation.	got7fsn_ti	inhibition of hepatocyte differentiation|negative regulation of liver cell differentiation|downregulation of hepatocyte differentiation|down regulation of hepatocyte differentiation|down-regulation of hepatocyte differentiation													biological_process											owl:Class	
GO:0102234	biolink:NamedThing	but-1-en-3-one reductase activity	Catalysis of the reaction: buten-2-one + NADPH + H+ <=> butan-2-one + NADP.	got7fsn_ti												MetaCyc:RXN-12293		molecular_function											owl:Class	
GO:0060476	biolink:NamedThing	protein localization involved in acrosome reaction	The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.	got7fsn_ti	protein localisation involved in acrosome reaction													biological_process											owl:Class	
GO:0047604	biolink:NamedThing	acetoin racemase activity	Catalysis of the reaction: (S)-acetoin = (R)-acetoin.	got7fsn_ti	acetylmethylcarbinol racemase activity											KEGG_REACTION:R02949|RHEA:12092|EC:5.1.2.4|MetaCyc:ACETOIN-RACEMASE-RXN		molecular_function											owl:Class	
GO:0005925	biolink:NamedThing	focal adhesion	A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ).	got7fsn_ti	HAJ|connecting hemi-adherens junction|hemi-adherens junction|adhesion plaque|focal contact										GO:0008357|GO:0005926	Wikipedia:Focal_adhesion		cellular_component											owl:Class	
GO:0052810	biolink:NamedThing	1-phosphatidylinositol-5-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+).	got7fsn_ti	ATP:1-phosphatidyl-1D-myo-inositol 5-phosphotransferase activity|1-phosphatidylinositol 5-kinase activity						ai	2011-10-21T03:37:20Z				Reactome:R-HSA-1675810|Reactome:R-HSA-1675866|RHEA:44680		molecular_function											owl:Class	
GO:0046265	biolink:NamedThing	thiocyanate catabolic process	The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.	got7fsn_ti	thiocyanate breakdown|thiocyanate catabolism|thiocyanate degradation													biological_process											owl:Class	
GO:0047415	biolink:NamedThing	D-benzoylarginine-4-nitroanilide amidase activity	Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H(2)O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H(+).	got7fsn_ti	D-BAPA-ase activity|N-benzoyl-D-arginine-4-nitroanilide amidohydrolase activity|benzoyl-D-arginine arylamidase activity											KEGG_REACTION:R04113|RHEA:14421|MetaCyc:3.5.1.72-RXN|EC:3.5.1.72		molecular_function											owl:Class	
GO:0018564	biolink:NamedThing	carbazole 1,9a-dioxygenase activity	Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol.	got7fsn_ti	carbazole 1,9alpha-dioxygenase activity											EC:1.13.11.-|UM-BBD_reactionID:r0456		molecular_function											owl:Class	
GO:0075505	biolink:NamedThing	entry of intact viral capsid into host nucleus through nuclear pore complex	Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC).	got7fsn_ti					This mechanism is used by viruses with capsids small enough to cross the nuclear pore complex, such as the single-stranded (ss) DNA viruses Parvoviridae, Circoviridae and Geminiviridae.		jl	2011-07-26T04:35:03Z						biological_process											owl:Class	
GO:0075732	biolink:NamedThing	viral penetration into host nucleus	The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid.	got7fsn_ti	viral import into host nucleus|viral entry into host nucleus						jl	2009-05-01T02:43:16Z				VZ:989		biological_process											owl:Class	
GO:0047794	biolink:NamedThing	cyclohexadienyl dehydrogenase activity	Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.	got7fsn_ti	L-arogenate:NAD+ oxidoreductase activity|arogenic dehydrogenase activity|L-arogenate:NAD+ oxidoreductase (decarboxylating)|L-arogenate:NAD(+) oxidoreductase activity|arogenate dehydrogenase activity|pretyrosine dehydrogenase activity											RHEA:12256|EC:1.3.1.43|MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0033410	biolink:NamedThing	UAC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UAC codon.	got7fsn_ti	tyrosine tRNA|TAC codon-amino acid adaptor activity				Note that in the standard genetic code, TAC codes for tyrosine.									molecular_function											owl:Class	
GO:0002940	biolink:NamedThing	tRNA N2-guanine methylation	The process whereby a guanine in a tRNA is methylated at the N2 position of guanine.	got7fsn_ti	tRNA m2-guanine biosynthesis						hjd	2012-11-09T16:23:41Z						biological_process											owl:Class	
GO:0042300	biolink:NamedThing	beta-amyrin synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin.	got7fsn_ti	oxidosqualene:beta-amyrin cyclase activity											MetaCyc:RXN-7570|EC:5.4.99.-		molecular_function											owl:Class	
GO:0097494	biolink:NamedThing	regulation of vesicle size	Any process that modulates the size of a vesicle.	got7fsn_ti							pr	2013-08-06T11:48:51Z						biological_process											owl:Class	
GO:0032141	biolink:NamedThing	single cytosine insertion binding	Binding to a double-stranded DNA region containing a single cytosine insertion or a deletion that results in an unpaired cytosine.	got7fsn_ti														molecular_function											owl:Class	
GO:0072518	biolink:NamedThing	Rho-dependent protein serine/threonine kinase activity	Rho GTPase-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	got7fsn_ti	ROCK kinase activity|Rho-associated protein kinase activity				This reaction requires binding of the GTPase Rho.		mah	2010-12-22T11:07:29Z						molecular_function											owl:Class	
GO:0008234	biolink:NamedThing	cysteine-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	got7fsn_ti	cysteine protease activity|thiol protease activity										GO:0004220	Reactome:R-HSA-2022381|Reactome:R-HSA-5660752|Reactome:R-HSA-2467775|Reactome:R-HSA-2467809		molecular_function											owl:Class	
GO:0102106	biolink:NamedThing	curcumin synthase activity	Catalysis of the reaction: feruloylacetyl-CoA + feruloyl-CoA(4-) + H2O <=> curcumin + 2 coenzyme A(4-) + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-11226|EC:2.3.1.217|RHEA:34823		molecular_function											owl:Class	
GO:0050331	biolink:NamedThing	thiamine-diphosphate kinase activity	Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate.	got7fsn_ti	thiamin diphosphate kinase activity|ATP:thiamin-diphosphate phosphotransferase activity|thiamin diphosphate phosphotransferase activity|ATP:thiamine-diphosphate phosphotransferase activity|thiamin pyrophosphate kinase activity|protein bound thiamin diphosphate:ATP phosphoryltransferase activity|thiamin-diphosphate kinase activity|thiamine diphosphate kinase activity|TDP kinase activity											EC:2.7.4.15|RHEA:11240|Reactome:R-HSA-997381|MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN		molecular_function											owl:Class	
GO:0051566	biolink:NamedThing	anthocyanidin-3-glucoside rhamnosyltransferase activity	Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP.	got7fsn_ti	anthocyanidin 3-glucoside-rhamnosyltransferase activity|3RT activity													molecular_function											owl:Class	
GO:0010630	biolink:NamedThing	regulation of transcription, start site selection	Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template.	got7fsn_ti														biological_process											owl:Class	
GO:0019219	biolink:NamedThing	regulation of nucleobase-containing compound metabolic process	Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.	got7fsn_ti	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism													biological_process											owl:Class	
GO:0034779	biolink:NamedThing	4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity	Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r1004		molecular_function											owl:Class	
GO:0070442	biolink:NamedThing	integrin alphaIIb-beta3 complex	An integrin complex that comprises one alphaIIb subunit and one beta3 subunit.	got7fsn_ti	alphaIIb-beta3 integrin complex|ITGA2B-ITGB3 complex													cellular_component											owl:Class	
GO:0071354	biolink:NamedThing	cellular response to interleukin-6	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.	got7fsn_ti	cellular response to IL-6						mah	2009-12-11T02:51:14Z						biological_process											owl:Class	
GO:0050043	biolink:NamedThing	lactate racemase activity	Catalysis of the reaction: (S)-lactate = (R)-lactate.	got7fsn_ti	hydroxyacid racemase activity|lacticoracemase activity|lactic acid racemase activity											RHEA:10960|EC:5.1.2.1|MetaCyc:LACTATE-RACEMASE-RXN|KEGG_REACTION:R01450		molecular_function											owl:Class	
GO:0015279	biolink:NamedThing	store-operated calcium channel activity	A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.	got7fsn_ti												Reactome:R-HSA-434798		molecular_function											owl:Class	
GO:0043158	biolink:NamedThing	heterocyst differentiation	The process in which a relatively unspecialized cell acquires specialized features of a heterocyst, a differentiated cell in certain cyanobacteria whose purpose is to fix nitrogen.	got7fsn_ti	heterocyst biosynthesis|heterocyst formation|heterocyst cell differentiation													biological_process											owl:Class	
GO:0022007	biolink:NamedThing	convergent extension involved in neural plate elongation	The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate.	got7fsn_ti														biological_process											owl:Class	
GO:0102293	biolink:NamedThing	pheophytinase b activity	Catalysis of the reaction: pheophytin b + H2O <=> H+ + pheophorbide b + phytol.	got7fsn_ti												MetaCyc:RXN-12686|EC:3.1.1.14		molecular_function											owl:Class	
GO:0120218	biolink:NamedThing	host interaction involved in quorum sensing	A quorum sensing process that is modulated by some interaction with a host cell or organism.	got7fsn_ti							krc	2019-11-01T21:52:08Z						biological_process											owl:Class	
GO:0033397	biolink:NamedThing	zeatin metabolic process	The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	got7fsn_ti	zeatin metabolism													biological_process											owl:Class	
GO:0047027	biolink:NamedThing	benzyl-2-methyl-hydroxybutyrate dehydrogenase activity	Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) = benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH.	got7fsn_ti	benzyl 2-methyl-3-hydroxybutyrate dehydrogenase activity|benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase activity											EC:1.1.1.217|RHEA:16405|KEGG_REACTION:R04370|MetaCyc:1.1.1.217-RXN		molecular_function											owl:Class	
GO:0046537	biolink:NamedThing	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate.	got7fsn_ti	PGAM-i													molecular_function											owl:Class	
GO:0030881	biolink:NamedThing	beta-2-microglobulin binding	Binding to beta-2-microglobulin.	got7fsn_ti														molecular_function											owl:Class	
GO:0042730	biolink:NamedThing	fibrinolysis	A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.	got7fsn_ti												Wikipedia:Fibrinolysis		biological_process											owl:Class	
GO:0034922	biolink:NamedThing	4,5-dihydroxypyrene dioxygenase activity	Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0936		molecular_function											owl:Class	
GO:0090254	biolink:NamedThing	cell elongation involved in imaginal disc-derived wing morphogenesis	The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis.	got7fsn_ti							tb	2010-01-22T11:40:46Z						biological_process											owl:Class	
GO:0075055	biolink:NamedThing	positive regulation of penetration peg formation	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont penetration peg formation for entry into host|positive regulation of symbiont penetration peg initiation	https://github.com/geneontology/go-ontology/issues/18557			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.						GO:0075059			biological_process											owl:Class	
GO:0120259	biolink:NamedThing	7SK snRNP	A ribonucleoprotein complex that contains the 7SK snRNA. The 7SK snRNP plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb.	got7fsn_ti	snRNP 7SK	https://github.com/geneontology/go-ontology/issues/19981					krc	2020-09-15T22:01:31Z						cellular_component											owl:Class	
GO:0050384	biolink:NamedThing	urate-ribonucleotide phosphorylase activity	Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H(+) + urate.	got7fsn_ti	UAR phosphorylase activity|urate-ribonucleotide:phosphate D-ribosyltransferase activity|urate-ribonucleotide:phosphate alpha-D-ribosyltransferase activity											RHEA:13909|EC:2.4.2.16|MetaCyc:URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN|KEGG_REACTION:R02646		molecular_function											owl:Class	
GO:0047667	biolink:NamedThing	AMP-thymidine kinase activity	Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate.	got7fsn_ti	adenylic acid:deoxythymidine 5'-phosphotransferase activity|thymidine phosphotransferase activity|AMP:thymidine 5'-phosphotransferase activity|AMP:deoxythymidine kinase activity|AMP:deoxythymidine 5'-phosphotransferase activity|AMP:dThd kinase activity|adenylate-nucleoside phosphotransferase activity											MetaCyc:AMP--THYMIDINE-KINASE-RXN|RHEA:14913|EC:2.7.1.114		molecular_function											owl:Class	
GO:0016601	biolink:NamedThing	Rac protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.	got7fsn_ti	Rac mediated signal transduction													biological_process											owl:Class	
GO:0098532	biolink:NamedThing	histone H3-K27 trimethylation	The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone.	got7fsn_ti							dos	2013-10-18T14:11:17Z						biological_process											owl:Class	
GO:0008288	biolink:NamedThing	boss receptor activity	Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	got7fsn_ti	sevenless receptor activity													molecular_function											owl:Class	
GO:0035315	biolink:NamedThing	hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hair cell.	got7fsn_ti														biological_process											owl:Class	
GO:0018499	biolink:NamedThing	cis-2,3-dihydrodiol DDT dehydrogenase activity	Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT.	got7fsn_ti												UM-BBD_reactionID:r0451		molecular_function											owl:Class	
GO:0047986	biolink:NamedThing	hydrogen-sulfide S-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate.	got7fsn_ti	hydrogen-sulphide S-acetyltransferase activity|hydrogen-sulfide acetyltransferase activity|acetyl-CoA:hydrogen-sulfide S-acetyltransferase activity											RHEA:16625|EC:2.3.1.10|KEGG_REACTION:R01850|MetaCyc:HYDROGEN-SULFIDE-S-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0102580	biolink:NamedThing	cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-xylose <=> cyanidin 3-O-beta-D-sambubioside + UDP.	got7fsn_ti												EC:2.4.2.51|MetaCyc:RXN-15326|RHEA:35443		molecular_function											owl:Class	
GO:0016042	biolink:NamedThing	lipid catabolic process	The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.	got7fsn_ti	multicellular organism lipid catabolic process|multicellular organismal lipid catabolic process|lipid degradation|lipid breakdown|lipid catabolism|lipolysis										GO:0006724|GO:0044240	Wikipedia:Lipid_catabolism		biological_process											owl:Class	
GO:0022893	biolink:NamedThing	low-affinity tryptophan transmembrane transporter activity	Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low-affinity tryptophan permease activity										GO:0015510			molecular_function											owl:Class	
GO:0060710	biolink:NamedThing	chorio-allantoic fusion	The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.	got7fsn_ti							dph	2009-06-09T03:24:27Z						biological_process											owl:Class	
GO:0102999	biolink:NamedThing	UDP-glucose:2-hydroxylamino-4,6-dinitrotoluene-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 2-hydroxylamino-4,6-dinitrotoluene <=> 2-hydroxylamino-4,6-dinitrotoluene-O-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-9743		molecular_function											owl:Class	
GO:0051038	biolink:NamedThing	negative regulation of transcription involved in meiotic cell cycle	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle.	got7fsn_ti	inhibition of transcription during meiosis|down-regulation of transcription during meiosis|negative regulation of meiotic transcription|meiotic repression of transcription|downregulation of transcription during meiosis|down regulation of transcription during meiosis|negative regulation of transcription, meiotic													biological_process											owl:Class	
GO:0070038	biolink:NamedThing	rRNA (pseudouridine-N3-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.	got7fsn_ti														molecular_function											owl:Class	
GO:0098038	biolink:NamedThing	non-replicative transposition, DNA-mediated	Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.	got7fsn_ti	cut-and-paste transposition						bm	2012-07-20T16:47:50Z						biological_process											owl:Class	
GO:0039620	biolink:NamedThing	T=7 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres.	got7fsn_ti					Spherical viruses with T numbers greater than or equal to 7 are skewed. They are therefore described as either right-handed (dextro) or left-handed (laevo).		bf	2012-07-18T02:16:40Z				VZ:804		cellular_component											owl:Class	
GO:0110035	biolink:NamedThing	rDNA spacer replication fork barrier binding, bending	The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	got7fsn_ti							kmv	2017-07-17T21:09:50Z						molecular_function											owl:Class	
GO:0070753	biolink:NamedThing	interleukin-35 production	The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-35 secretion|interleukin-35 biosynthetic process|IL-35 production						mah	2009-06-23T01:25:11Z			GO:0070749|GO:0072626			biological_process											owl:Class	
GO:0050494	biolink:NamedThing	GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GSI anchor formation via N-glycyl-glycosylsphingolipidinositolethanolamine|GSI anchor synthesis via N-glycyl-glycosylsphingolipidinositolethanolamine|GSI anchor anabolism via N-glycyl-glycosylsphingolipidinositolethanolamine											RESID:AA0165		biological_process											owl:Class	
GO:0034009	biolink:NamedThing	isoprene synthase activity	Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene.	got7fsn_ti	ISPC|ISPS|dimethylallyl-diphosphate diphosphate-lyase (isoprene-forming) activity											EC:4.2.3.27|KEGG_REACTION:R08199|MetaCyc:4.2.3.27-RXN|RHEA:13369		molecular_function											owl:Class	
GO:0140492	biolink:NamedThing	metal-dependent deubiquitinase activity	Catalysis of the metal-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.	got7fsn_ti	metal-dependent ubiquitinyl-like hydrolase activity|metal-dependent ubiquitin-like hydrolase activity	https://github.com/geneontology/go-ontology/issues/17398					pg	2020-07-01T13:14:00Z						molecular_function											owl:Class	
GO:1990926	biolink:NamedThing	short-term synaptic potentiation	The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes.  This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability.  It occurs in a timeframe of tens to hundreds of milliseconds.	got7fsn_ti	synaptic facilitation				The mechanism of short term potentiation is thought to be either increased influx of calcium into the presynapse (Zucker and Regeh, 2002 PMID:11826273) increased sensitivity to calcium (Jackman et al., 2016 PMID:26738595) or both.		sp	2016-02-12T13:17:18Z						biological_process											owl:Class	
GO:0047929	biolink:NamedThing	gluconate dehydratase activity	Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.	got7fsn_ti	D-gluconate dehydratase activity|D-gluconate hydro-lyase activity|D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)											MetaCyc:GLUCONATE-DEHYDRATASE-RXN|RHEA:21612|EC:4.2.1.39|KEGG_REACTION:R01538		molecular_function											owl:Class	
GO:0035319	biolink:NamedThing	imaginal disc-derived wing hair elongation	Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.	got7fsn_ti	wing hair elongation|wing prehair extension													biological_process											owl:Class	
GO:0052322	biolink:NamedThing	positive regulation of phytoalexin biosynthetic process	Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.	got7fsn_ti	upregulation of phytoalexin biosynthesis|activation of phytoalexin biosynthesis|up-regulation of phytoalexin biosynthesis|up regulation of phytoalexin biosynthesis|positive regulation of phytoalexin biosynthesis|stimulation of phytoalexin biosynthesis													biological_process											owl:Class	
GO:0051749	biolink:NamedThing	indole acetic acid carboxyl methyltransferase activity	Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine.	got7fsn_ti	IAA carboxyl methyltransferase activity													molecular_function											owl:Class	
GO:0052659	biolink:NamedThing	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.	got7fsn_ti	D-myo-inositol (1,3,4,5)-polyphosphate 5-phosphatase activity|5PTase activity|type II inositol polyphosphate 5-phosphatase activity|inositol polyphosphate-5-phosphatase activity|Ins(1,3,4,5)P(4) 5-phosphatase activity|type I inositol-polyphosphate phosphatase activity|Ins(1,3,4,5)P4 5-phosphatase activity											Reactome:R-HSA-1855218|RHEA:11392|KEGG_REACTION:R03430|MetaCyc:RXN-8730|EC:3.1.3.56|Reactome:R-HSA-1855213		molecular_function											owl:Class	
GO:0106347	biolink:NamedThing	U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity	Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.	got7fsn_ti							hjd	2020-12-18T15:11:10Z				RHEA:62672		molecular_function											owl:Class	
GO:0047299	biolink:NamedThing	tryptophan-phenylpyruvate transaminase activity	Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine.	got7fsn_ti	L-tryptophan:phenylpyruvate aminotransferase activity|tryptophan--phenylpyruvate aminotransferase activity|tryptophan-phenylpyruvate aminotransferase activity|L-tryptophan-alpha-ketoisocaproate aminotransferase activity											KEGG_REACTION:R01376|MetaCyc:2.6.1.28-RXN|RHEA:13741|EC:2.6.1.28		molecular_function											owl:Class	
GO:0010254	biolink:NamedThing	nectary development	The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0030288	biolink:NamedThing	outer membrane-bounded periplasmic space	The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.	got7fsn_ti	outer membrane bounded periplasmic space|outer membrane-enclosed periplasmic space											Wikipedia:Periplasmic_space		cellular_component											owl:Class	
GO:0042597	biolink:NamedThing	periplasmic space	The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).	got7fsn_ti	periplasm										GO:0005620			cellular_component											owl:Class	
GO:0043416	biolink:NamedThing	regulation of skeletal muscle tissue regeneration	Any process that modulates the frequency, rate or extent of skeletal muscle.	got7fsn_ti														biological_process											owl:Class	
GO:1900605	biolink:NamedThing	tensidol A biosynthetic process	The chemical reactions and pathways resulting in the formation of tensidol A.	got7fsn_ti	tensidol A anabolism|tensidol A synthesis|tensidol A biosynthesis|tensidol A formation						di	2012-05-15T06:58:16Z						biological_process											owl:Class	
GO:0004149	biolink:NamedThing	dihydrolipoyllysine-residue succinyltransferase activity	Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide.	got7fsn_ti	dihydrolipoyl transsuccinylase activity|lipoyl transsuccinylase activity|dihydrolipolyl transsuccinylase activity|succinyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-succinyltransferase activity|dihydrolipoic transsuccinylase activity|lipoate succinyltransferase (Escherichia coli) activity|succinyl-CoA:dihydrolipoate S-succinyltransferase activity|succinyl-CoA:dihydrolipoamide S-succinyltransferase activity|lipoic transsuccinylase activity|lipoate succinyltransferase activity|enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase activity|dihydrolipoamide succinyltransferase activity|succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity|dihydrolipoamide S-succinyltransferase activity											EC:2.3.1.61|RHEA:15213		molecular_function											owl:Class	
GO:2000253	biolink:NamedThing	positive regulation of feeding behavior	Any process that activates or increases the frequency, rate or extent of feeding behavior.	got7fsn_ti	positive regulation of drinking|positive regulation of behavioural response to food|positive regulation of behavioral response to food|positive regulation of eating|positive regulation of feeding behaviour						yaf	2010-11-18T11:24:18Z						biological_process											owl:Class	
GO:0032018	biolink:NamedThing	2-methylbutanol:NADP oxidoreductase activity	Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+.	got7fsn_ti	2-methylbutyraldehyde reductase (NADP) activity|2-methylbutanal reductase (NADP) activity													molecular_function											owl:Class	
GO:0003389	biolink:NamedThing	retrograde extension	The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.	got7fsn_ti							dph	2009-12-09T09:22:03Z						biological_process											owl:Class	
GO:0070370	biolink:NamedThing	cellular heat acclimation	Any process that increases heat tolerance of a cell in response to high temperatures.	got7fsn_ti	cellular thermotolerance													biological_process											owl:Class	
GO:0004063	biolink:NamedThing	aryldialkylphosphatase activity	Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol.	got7fsn_ti	organophosphorus acid anhydrase activity|aryltriphosphate dialkylphosphohydrolase activity|pirimiphos-methyloxon esterase activity|esterase E4|paraoxon hydrolase activity|phosphotriesterase activity|A-esterase activity|paraoxonase activity|OPH|aryltriphosphatase activity|organophosphate hydrolase activity|esterase B1|organophosphate esterase activity|organophosphorus hydrolase activity|paraoxon esterase activity											RHEA:18053|UM-BBD_enzymeID:e0054|EC:3.1.8.1|MetaCyc:ARYLDIALKYLPHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0043971	biolink:NamedThing	histone H3-K18 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone.	got7fsn_ti	histone H3K18 acetylation|histone H3 acetylation at K18													biological_process											owl:Class	
GO:0098018	biolink:NamedThing	viral capsid, minor subunit	The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits.	got7fsn_ti	minor capsomere|minor head protein						bm	2012-07-19T11:28:18Z						cellular_component											owl:Class	
GO:2001141	biolink:NamedThing	regulation of RNA biosynthetic process	Any process that modulates the frequency, rate or extent of RNA biosynthetic process.	got7fsn_ti	regulation of RNA anabolism|regulation of RNA biosynthesis|regulation of RNA synthesis|regulation of RNA formation						dph	2011-10-17T11:36:25Z						biological_process											owl:Class	
GO:0031819	biolink:NamedThing	P2Y10 nucleotide receptor binding	Binding to a P2Y10 nucleotide receptor.	got7fsn_ti	P2Y10 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0018047	biolink:NamedThing	C-terminal peptidyl-phenylalanine amidation	The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0094		biological_process											owl:Class	
GO:0045438	biolink:NamedThing	delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity	Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.	got7fsn_ti	ACV synthetase activity													molecular_function											owl:Class	
GO:0018469	biolink:NamedThing	myrtenal dehydrogenase activity	Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid.	got7fsn_ti												UM-BBD_reactionID:r0711		molecular_function											owl:Class	
GO:0006711	biolink:NamedThing	estrogen catabolic process	The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.	got7fsn_ti	estrogen catabolism|estrogen degradation|oestrogen catabolism|oestrogen catabolic process|estrogen breakdown													biological_process											owl:Class	
GO:0004569	biolink:NamedThing	glycoprotein endo-alpha-1,2-mannosidase activity	Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane.	got7fsn_ti	endo-alpha-mannosidase activity|endomannosidase activity|glycoprotein glucosylmannohydrolase activity|glucosyl mannosidase activity|glucosylmannosidase activity											RHEA:54824|Reactome:R-HSA-964759|MetaCyc:3.2.1.130-RXN|EC:3.2.1.130		molecular_function											owl:Class	
GO:0071892	biolink:NamedThing	thrombocyte activation	A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals.	got7fsn_ti	blood coagulation, thrombocyte activation						mah	2010-09-14T03:06:33Z						biological_process											owl:Class	
GO:0103075	biolink:NamedThing	indole-3-pyruvate monooxygenase activity	Catalysis of the reaction: 3-(indol-3-yl)pyruvate + NADPH + O2 + H+ <=> indole-3-acetate + carbon dioxide + NADP + H2O.	got7fsn_ti												MetaCyc:RXNDQC-2|RHEA:34331|EC:1.14.13.168		molecular_function											owl:Class	
GO:0098744	biolink:NamedThing	1-phosphatidylinositol 4-kinase activator activity	Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.	got7fsn_ti														molecular_function											owl:Class	
GO:0110064	biolink:NamedThing	lncRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length.	got7fsn_ti	lncRNA degradation|lncRNA breakdown|lncRNA catabolism						kmv	2017-11-06T13:49:49Z						biological_process											owl:Class	
GO:0072185	biolink:NamedThing	metanephric cap development	The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.	got7fsn_ti							mah	2010-03-01T01:20:22Z						biological_process											owl:Class	
GO:0140580	biolink:NamedThing	mitochondrion autophagosome adaptor activity	The binding activity of a molecule that brings together a mitochondrial membrane and an autophagosome during mitophagy.	got7fsn_ti	mitophagy receptor	https://github.com/geneontology/go-ontology/issues/20668					pg	2021-01-18T11:03:49Z						molecular_function											owl:Class	
GO:0021977	biolink:NamedThing	tectospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.	got7fsn_ti														biological_process											owl:Class	
GO:0061896	biolink:NamedThing	all-trans retinol 3,4-desaturase activity	Catalysis of the reaction: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin].	got7fsn_ti							dph	2017-06-12T14:49:30Z				RHEA:50292		molecular_function											owl:Class	
GO:0090672	biolink:NamedThing	telomerase RNA localization	Any process in which telomerase RNA is transported to, or maintained in, a specific location.	got7fsn_ti							tb	2015-12-17T14:08:01Z						biological_process											owl:Class	
GO:0004789	biolink:NamedThing	thiamine-phosphate diphosphorylase activity	Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate.	got7fsn_ti	thiamin-phosphate pyrophosphorylase activity|TMP-PPase activity|thiamine-phosphate synthase activity|TMP pyrophosphorylase activity|thiamine phosphate pyrophosphorylase activity|thiamin-phosphate diphosphorylase activity|TMP diphosphorylase activity|thiamine-phosphate pyrophosphorylase activity|thiamine monophosphate pyrophosphorylase activity|2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)thiazole 2-methyl-4-aminopyrimidine-5-methenyltransferase activity											RHEA:22328|KEGG_REACTION:R03223|EC:2.5.1.3|MetaCyc:THI-P-SYN-RXN		molecular_function											owl:Class	
GO:0010785	biolink:NamedThing	clathrin coating of Golgi vesicle, plasma membrane to endosome targeting	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat.	got7fsn_ti														biological_process											owl:Class	
GO:0090037	biolink:NamedThing	positive regulation of protein kinase C signaling	Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	positive regulation of protein kinase C signalling cascade|positive regulation of protein kinase C signaling cascade						tb	2009-08-03T11:28:44Z						biological_process											owl:Class	
GO:0106156	biolink:NamedThing	peptidyl-lysine 4-dioxygenase activity	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2.	got7fsn_ti							hjd	2018-11-26T14:59:18Z				RHEA:57156		molecular_function											owl:Class	
GO:1901731	biolink:NamedThing	positive regulation of platelet aggregation	Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.	got7fsn_ti	positive regulation of thrombocyte aggregation|upregulation of thrombocyte aggregation|up regulation of platelet aggregation|up-regulation of thrombocyte aggregation|up-regulation of blood platelet aggregation|activation of blood platelet aggregation|up-regulation of platelet aggregation|activation of platelet aggregation|positive regulation of blood platelet aggregation|up regulation of thrombocyte aggregation|up regulation of blood platelet aggregation|upregulation of platelet aggregation|activation of thrombocyte aggregation|upregulation of blood platelet aggregation						pr	2013-01-10T13:25:39Z						biological_process											owl:Class	
GO:0060812	biolink:NamedThing	orthodenticle mRNA localization	Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.	got7fsn_ti	orthodenticle mRNA localisation						dph	2009-08-07T09:39:01Z						biological_process											owl:Class	
GO:0031133	biolink:NamedThing	regulation of axon diameter	Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained.	got7fsn_ti														biological_process											owl:Class	
GO:0050770	biolink:NamedThing	regulation of axonogenesis	Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.	got7fsn_ti														biological_process											owl:Class	
GO:0036435	biolink:NamedThing	K48-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein.	got7fsn_ti							bf	2013-09-18T14:51:06Z				Reactome:R-HSA-5683077		molecular_function											owl:Class	
GO:0018617	biolink:NamedThing	4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity	Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol.	got7fsn_ti	4-aminobenzenesulphonate 3,4-dioxygenase (deaminating) activity											UM-BBD_reactionID:r0580|EC:1.14.12.-		molecular_function											owl:Class	
GO:0090510	biolink:NamedThing	anticlinal cell division	A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file.	got7fsn_ti							tb	2012-11-21T11:52:40Z						biological_process											owl:Class	
GO:0000386	biolink:NamedThing	second spliceosomal transesterification activity	Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.	got7fsn_ti	lariat formation, 5'-splice site cleavage|3'-splice site cleavage, exon ligation													molecular_function											owl:Class	
GO:0003114	biolink:NamedThing	positive regulation of heart rate by circulating norepinephrine	The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction.	got7fsn_ti	positive regulation of heart rate by circulating noradrenaline													biological_process											owl:Class	
GO:0051011	biolink:NamedThing	microtubule minus-end binding	Binding to the minus end of a microtubule.	got7fsn_ti														molecular_function											owl:Class	
GO:0008017	biolink:NamedThing	microtubule binding	Binding to a microtubule, a filament composed of tubulin monomers.	got7fsn_ti	microtubule/chromatin interaction|microtubule severing activity											Reactome:R-HSA-9614343		molecular_function											owl:Class	
GO:0098861	biolink:NamedThing	actin filament bundle of filopodium	A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0008774	biolink:NamedThing	acetaldehyde dehydrogenase (acetylating) activity	Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+.	got7fsn_ti	aldehyde dehydrogenase (acylating) activity|acylating acetaldehyde dehydrogenase activity|ADA|DmpF|acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)											EC:1.2.1.10|RHEA:23288|MetaCyc:ACETALD-DEHYDROG-RXN		molecular_function											owl:Class	
GO:0019695	biolink:NamedThing	choline metabolic process	The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	got7fsn_ti	choline metabolism													biological_process											owl:Class	
GO:0031987	biolink:NamedThing	locomotion involved in locomotory behavior	Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.	got7fsn_ti	locomotion during locomotory behaviour													biological_process											owl:Class	
GO:0043730	biolink:NamedThing	5-ureido-4-imidazole carboxylate hydrolase activity	Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2.	got7fsn_ti														molecular_function											owl:Class	
GO:0001195	biolink:NamedThing	maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter.	got7fsn_ti	maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase III promoter						krc	2011-09-02T02:41:29Z						biological_process											owl:Class	
GO:0098821	biolink:NamedThing	BMP receptor activity	Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0034837	biolink:NamedThing	2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity	Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1179		molecular_function											owl:Class	
GO:0005835	biolink:NamedThing	fatty acid synthase complex	A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA.	got7fsn_ti	FAS complex|cytosolic type I fatty acid synthase complex|holo-[acyl-carrier-protein] synthase complex|cytosolic fatty acid synthase complex|fatty acid synthetase complex|cytosolic FAS complex|cytosolic type I FAS complex										GO:0031373|GO:0031374	Wikipedia:Fatty_acid_synthetase_complex		cellular_component											owl:Class	
GO:0090719	biolink:NamedThing	adaptive immune effector response involving T cells and B lineage cells	An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells.	got7fsn_ti							tb	2016-11-11T12:43:26Z						biological_process											owl:Class	
GO:0080085	biolink:NamedThing	signal recognition particle, chloroplast targeting	A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to the chloroplast.	got7fsn_ti							dhl	2009-04-22T02:36:01Z						cellular_component											owl:Class	
GO:0018471	biolink:NamedThing	4-chlorobenzaldehyde oxidase activity	Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-.	got7fsn_ti												EC:1.14.13.-|UM-BBD_reactionID:r0447		molecular_function											owl:Class	
GO:0030229	biolink:NamedThing	very-low-density lipoprotein particle receptor activity	Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.	got7fsn_ti	VLDL receptor|apolipoprotein E receptor activity|very-low-density lipoprotein receptor activity											Wikipedia:VLDL_receptor		molecular_function											owl:Class	
GO:0075720	biolink:NamedThing	establishment of episomal latency	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity.	got7fsn_ti	establishment of plasmid latency|establishment as a plasmid prophage						jl	2009-11-26T03:57:44Z						biological_process											owl:Class	
GO:0097109	biolink:NamedThing	neuroligin family protein binding	Binding to a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.	got7fsn_ti							pr	2011-07-28T05:15:22Z						molecular_function											owl:Class	
GO:0016176	biolink:NamedThing	superoxide-generating NADPH oxidase activator activity	Increases the activity of the enzyme superoxide-generating NADPH oxidase.	got7fsn_ti	neutrophil cytosol factor 2													molecular_function											owl:Class	
GO:0140121	biolink:NamedThing	Lewy body formation	The aggregation, arrangement and bonding together of a set of components to form a Lewy body.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14160					pg	2017-10-25T06:59:12Z						biological_process											owl:Class	
GO:0090741	biolink:NamedThing	pigment granule membrane	Any membrane that is part of a pigment granule.	got7fsn_ti							tb	2017-05-16T22:33:39Z						cellular_component											owl:Class	
GO:0090541	biolink:NamedThing	MIT domain binding	Binding to a MIT protein domain. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking.	got7fsn_ti							tb	2013-02-14T17:11:29Z						molecular_function											owl:Class	
GO:0090629	biolink:NamedThing	lagging strand initiation	The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started.	got7fsn_ti							tb	2015-02-11T14:37:13Z						biological_process											owl:Class	
GO:0003345	biolink:NamedThing	proepicardium cell migration involved in pericardium morphogenesis	The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart.	got7fsn_ti							dph	2009-12-01T10:49:32Z						biological_process											owl:Class	
GO:0060973	biolink:NamedThing	cell migration involved in heart development	The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.	got7fsn_ti							dph	2009-10-06T10:53:49Z						biological_process											owl:Class	
GO:0015055	biolink:NamedThing	secretin receptor activity	Combining with secretin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0047274	biolink:NamedThing	galactinol-sucrose galactosyltransferase activity	Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol.	got7fsn_ti	alpha-D-galactosyl-(1->3)-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity|1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity|galactinol:sucrose 6-galactosyl transferase activity|raffinose synthase activity|galactosyltransferase, galactinol-sucrose											EC:2.4.1.82|RHEA:20161|MetaCyc:2.4.1.82-RXN		molecular_function											owl:Class	
GO:0018396	biolink:NamedThing	peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine	The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine.	got7fsn_ti												RESID:AA0235		biological_process											owl:Class	
GO:0000906	biolink:NamedThing	6,7-dimethyl-8-ribityllumazine synthase activity	Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate.	got7fsn_ti	lumazine synthase activity											RHEA:26152|MetaCyc:LUMAZINESYN-RXN|EC:2.5.1.78		molecular_function											owl:Class	
GO:0090143	biolink:NamedThing	nucleoid organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined.	got7fsn_ti	nucleoid organisation						tb	2009-12-08T02:35:48Z						biological_process											owl:Class	
GO:0008873	biolink:NamedThing	gluconate 2-dehydrogenase activity	Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+.	got7fsn_ti	2-keto-D-gluconate reductase activity|2-ketogluconate reductase activity|D-gluconate:NADP+ oxidoreductase activity											EC:1.1.1.215|MetaCyc:1.1.1.215-RXN|RHEA:16653		molecular_function											owl:Class	
GO:0018254	biolink:NamedThing	peptidyl-tyrosine adenylylation	The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine.	got7fsn_ti	peptidyl-tyrosine adenylation											RESID:AA0203		biological_process											owl:Class	
GO:0039511	biolink:NamedThing	suppression by virus of host interferon receptor activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host interferon receptor.	got7fsn_ti	inhibition of host interferon receptors by virus|inhibition by virus of host interferon receptor activity|down-regulation by virus of host interferon receptor activity|negative regulation by virus of host interferon receptor activity|downregulation by virus of host interferon receptor activity						bf	2011-06-16T02:24:05Z				VZ:843		biological_process											owl:Class	
GO:0098787	biolink:NamedThing	mRNA cleavage involved in mRNA processing	Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide.	got7fsn_ti														biological_process											owl:Class	
GO:0006379	biolink:NamedThing	mRNA cleavage	Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.	got7fsn_ti	cleavage stimulation factor activity													biological_process											owl:Class	
GO:0002587	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide antigen via MHC class II	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.	got7fsn_ti	downregulation of antigen processing and presentation of peptide antigen via MHC class II|down regulation of antigen processing and presentation of peptide antigen via MHC class II|negative regulation of peptide antigen processing and presentation via MHC class II|down-regulation of antigen processing and presentation of peptide antigen via MHC class II|inhibition of antigen processing and presentation of peptide antigen via MHC class II													biological_process											owl:Class	
GO:0052772	biolink:NamedThing	brefeldin A esterase activity	Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone.	got7fsn_ti	brefeldin A hydrolase activity|BFA esterase activity						ai	2011-10-03T12:01:00Z						molecular_function											owl:Class	
GO:0061002	biolink:NamedThing	negative regulation of dendritic spine morphogenesis	Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	got7fsn_ti							dph	2010-01-20T09:34:49Z						biological_process											owl:Class	
GO:0061000	biolink:NamedThing	negative regulation of dendritic spine development	Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-01-20T09:29:18Z						biological_process											owl:Class	
GO:0070166	biolink:NamedThing	enamel mineralization	The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.	got7fsn_ti	enamel formation													biological_process											owl:Class	
GO:0072563	biolink:NamedThing	endothelial microparticle	A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell.	got7fsn_ti							mah	2011-01-28T01:53:25Z						cellular_component											owl:Class	
GO:0043748	biolink:NamedThing	O-succinylbenzoate synthase activity	Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.	got7fsn_ti												EC:4.2.1.113		molecular_function											owl:Class	
GO:0097513	biolink:NamedThing	myosin II filament	A bipolar filament composed of myosin II molecules.	got7fsn_ti							pr	2013-10-16T13:06:20Z						cellular_component											owl:Class	
GO:0090494	biolink:NamedThing	dopamine uptake	The directed movement of dopamine into a cell.	got7fsn_ti							tb	2012-10-17T11:12:09Z						biological_process											owl:Class	
GO:0015872	biolink:NamedThing	dopamine transport	The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	got7fsn_ti														biological_process											owl:Class	
GO:0106299	biolink:NamedThing	resolution phase response	An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.	got7fsn_ti					Acute inflammatory response(s) are self-limited, resolve on their own and classically divide into initiation and resolution phases. SPMs are a superfamily of proresolving mediators that include resolvins (Rvs), protectins (PDs), maresins (MaRs) and lipoxins (LXs).		hjd	2020-08-25T13:54:05Z						biological_process											owl:Class	
GO:0033895	biolink:NamedThing	ribonuclease [poly-(U)-specific] activity	Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.	got7fsn_ti	uracil-specific RNase activity|ribonuclease (uracil-specific) activity|uracil-specific endoribonuclease activity											EC:3.1.26.9		molecular_function											owl:Class	
GO:0004845	biolink:NamedThing	uracil phosphoribosyltransferase activity	Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil.	got7fsn_ti	UPRTase activity|UMP pyrophosphorylase activity|uridine monophosphate pyrophosphorylase activity|UMP:diphosphate phospho-alpha-D-ribosyltransferase activity|UMP diphosphorylase activity|uridine 5'-phosphate pyrophosphorylase activity|uridylic pyrophosphorylase activity|uridylate pyrophosphorylase activity|UMP:pyrophosphate phosphoribosyltransferase activity											KEGG_REACTION:R00966|MetaCyc:URACIL-PRIBOSYLTRANS-RXN|EC:2.4.2.9|RHEA:13017		molecular_function											owl:Class	
GO:0106312	biolink:NamedThing	methylenetetrahydrofolate reductase NADH activity	Catalysis of the reaction: 5-methyltetrahydrofolate + NAD + = 5,10-methylenetetrahydrofolate + NADH + H+.	got7fsn_ti							hjd	2020-09-23T14:20:07Z				RHEA:19821		molecular_function											owl:Class	
GO:0051911	biolink:NamedThing	Methanosarcina-phenazine hydrogenase activity	Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine.	got7fsn_ti	coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|methylviologen-reducing hydrogenase activity|methanophenazine hydrogenase activity|hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase activity											MetaCyc:RXN-7733|EC:1.12.98.3|RHEA:24436		molecular_function											owl:Class	
GO:0019639	biolink:NamedThing	6-hydroxycineole catabolic process	The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.	got7fsn_ti	6-hydroxycineole breakdown|6-endo-hydroxycineole catabolic process|6-hydroxycineole degradation|6-hydroxycineole catabolism|hydroxycineol catabolic process|6-endo-hydroxycineole catabolism|hydroxycineol catabolism											MetaCyc:6-HYDROXYCINEOLE-DEGRADATION-PWY		biological_process											owl:Class	
GO:0033954	biolink:NamedThing	alpha-neoagaro-oligosaccharide hydrolase activity	Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose.	got7fsn_ti	alpha-neoagarooligosaccharide hydrolase activity|alpha-NAOS hydrolase activity|alpha-neoagaro-oligosaccharide 3-glycohydrolase activity											EC:3.2.1.159|MetaCyc:3.2.1.159-RXN		molecular_function											owl:Class	
GO:0018968	biolink:NamedThing	tetrahydrofuran metabolic process	The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems.	got7fsn_ti	THF metabolism|tetrahydrofuran metabolism|THF metabolic process											UM-BBD_pathwayID:thf		biological_process											owl:Class	
GO:0018581	biolink:NamedThing	hydroxyquinol 1,2-dioxygenase activity	Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate.	got7fsn_ti	hydroxyquinol dioxygenase activity|benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)											EC:1.13.11.37|MetaCyc:HYDROXYQUINOL-12-DIOXYGENASE-RXN|UM-BBD_reactionID:r0232|RHEA:19441		molecular_function											owl:Class	
GO:0097586	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p.	got7fsn_ti	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p dimer|Pmt4p-Pmt4p complex|dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p-Pmt4p dimer complex						pr	2014-03-02T18:19:05Z						cellular_component											owl:Class	
GO:0018972	biolink:NamedThing	toluene-4-sulfonate metabolic process	The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water.	got7fsn_ti	toluene-4-sulfonate metabolism|toluene-4-sulphonate metabolic process|4-methylbenzenesulfonate metabolism|4-toluenesulfonate metabolic process|toluene-4-sulphonate metabolism|4-methylbenzenesulfonate metabolic process|4-toluenesulfonate metabolism											UM-BBD_pathwayID:tsa|MetaCyc:TOLSULFDEG-PWY		biological_process											owl:Class	
GO:0070998	biolink:NamedThing	sensory perception of gravity	The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti							mah	2009-11-03T03:25:12Z						biological_process											owl:Class	
GO:0047499	biolink:NamedThing	calcium-independent phospholipase A2 activity	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.	got7fsn_ti	calcium-independent cytosolic phospholipase A2 activity											Reactome:R-HSA-8952251		molecular_function											owl:Class	
GO:0102583	biolink:NamedThing	cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A.	got7fsn_ti												MetaCyc:RXN-15329		molecular_function											owl:Class	
GO:0097678	biolink:NamedThing	SOCS family protein binding	Binding to a member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions.	got7fsn_ti	suppressor of cytokine signaling family protein binding						pr	2014-11-04T11:32:49Z						molecular_function											owl:Class	
GO:0102824	biolink:NamedThing	UDP-L-rhamnose:quercetin 3-O-rhamnosyltransferase activity	Catalysis of the reaction: quercetin-7-olate + UDP-L-rhamnose <=> H+ + quercetin 3-O-rhamnoside + UDP.	got7fsn_ti												MetaCyc:RXN-8267|RHEA:61160		molecular_function											owl:Class	
GO:0102549	biolink:NamedThing	1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + H2O <=> sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+.	got7fsn_ti												EC:3.1.1.26|MetaCyc:RXN-14912		molecular_function											owl:Class	
GO:0102889	biolink:NamedThing	beta-elemene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-elemene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8432		molecular_function											owl:Class	
GO:0072382	biolink:NamedThing	minus-end-directed vesicle transport along microtubule	The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.	got7fsn_ti	microtubule minus-end-directed vesicle localization|microtubule minus-end-directed vesicle distribution						mah	2010-12-01T04:12:59Z						biological_process											owl:Class	
GO:0072385	biolink:NamedThing	minus-end-directed organelle transport along microtubule	The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.	got7fsn_ti	microtubule minus-end-directed organelle distribution|microtubule minus-end-directed organelle localization						mah	2010-12-01T05:01:20Z						biological_process											owl:Class	
GO:0050155	biolink:NamedThing	ornithine(lysine) transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate.	got7fsn_ti	lysine/ornithine:2-oxoglutarate aminotransferase activity|L-ornithine(L-lysine):2-oxoglutarate-aminotransferase activity|L-ornithine:2-oxoglutarate-aminotransferase activity|ornithine(lysine) aminotransferase activity											MetaCyc:ORNITHINELYSINE-AMINOTRANSFERASE-RXN|EC:2.6.1.13		molecular_function											owl:Class	
GO:0031854	biolink:NamedThing	orexigenic neuropeptide QRFP receptor binding	Binding to an orexigenic neuropeptide QRFP receptor.	got7fsn_ti	orexigenic neuropeptide QRFP receptor ligand													molecular_function											owl:Class	
GO:0018827	biolink:NamedThing	1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity	Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU.	got7fsn_ti	DDMS dehydrochlorinase activity											UM-BBD_reactionID:r0515|EC:4.5.1.-		molecular_function											owl:Class	
GO:0033485	biolink:NamedThing	cyanidin 3-O-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.	got7fsn_ti	cyanidin 3-O-glucoside biosynthesis|cyanidin 3-O-glucoside anabolism|cyanidin 3-O-glucoside formation|cyanidin 3-O-glucoside synthesis											MetaCyc:PWY-5125		biological_process											owl:Class	
GO:0030619	biolink:NamedThing	U1 snRNA binding	Binding to a U1 small nuclear RNA (U1 snRNA).	got7fsn_ti					Note that this term may be useful for annotating other small nuclear RNAs (snRNAs).									molecular_function											owl:Class	
GO:0051260	biolink:NamedThing	protein homooligomerization	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	got7fsn_ti	protein homooligomer biosynthetic process|protein homooligomer assembly|protein homooligomerization activity|protein homooligomer biosynthesis|protein homooligomer formation													biological_process											owl:Class	
GO:0050403	biolink:NamedThing	trans-zeatin O-beta-D-glucosyltransferase activity	Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H(+) + UDP.	got7fsn_ti	UDP-glucose:trans-zeatin O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-zeatin O-glucosyltransferase activity|zeatin O-glucosyltransferase activity|zeatin O-beta-D-glucosyltransferase activity|zeatin O-b-D-glucosyltransferase activity|UDPglucose:trans-zeatin O-beta-D-glucosyltransferase activity											KEGG_REACTION:R02118|EC:2.4.1.203|RHEA:23224|MetaCyc:RXN-4723		molecular_function											owl:Class	
GO:0001762	biolink:NamedThing	beta-alanine transport	The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0051758	biolink:NamedThing	homologous chromosome movement towards spindle pole in meiosis I anaphase	The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase.	got7fsn_ti	meiosis I, homologous chromosome movement towards spindle pole|homologous chromosome movement towards spindle pole during meiosis I													biological_process											owl:Class	
GO:0047237	biolink:NamedThing	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP.	got7fsn_ti	UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-chondroitinacetylgalactosaminyltransferase I activity|N-acetylgalactosaminyltransferase I activity|uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I|glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity											MetaCyc:2.4.1.174-RXN|EC:2.4.1.174|RHEA:23464		molecular_function											owl:Class	
GO:0052812	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate 5-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).	got7fsn_ti	ATP:1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 5-phosphotransferase activity						ai	2011-10-21T03:52:02Z				Reactome:R-HSA-1675773|EC:2.7.1.153		molecular_function											owl:Class	
GO:0018616	biolink:NamedThing	trihydroxytoluene dioxygenase activity	Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate.	got7fsn_ti												MetaCyc:R305-RXN|UM-BBD_reactionID:r0093		molecular_function											owl:Class	
GO:0048150	biolink:NamedThing	behavioral response to ether	Any process that results in a change in the behavior of an organism as a result of an ether stimulus.	got7fsn_ti	behavioural response to ether													biological_process											owl:Class	
GO:0070663	biolink:NamedThing	regulation of leukocyte proliferation	Any process that modulates the frequency, rate or extent of leukocyte proliferation.	got7fsn_ti							mah	2009-05-28T05:30:39Z						biological_process											owl:Class	
GO:0080098	biolink:NamedThing	L-tyrosine:pyruvate aminotransferase activity	Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine.	got7fsn_ti							dhl	2009-04-23T03:47:53Z				MetaCyc:RXN3O-4157|EC:2.6.1.58		molecular_function											owl:Class	
GO:1990080	biolink:NamedThing	2-phenylethylamine receptor activity	Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity.	got7fsn_ti	beta-phenylethylamine receptor activity						sp	2013-04-30T10:53:19Z						molecular_function											owl:Class	
GO:0039652	biolink:NamedThing	activation by virus of host NF-kappaB transcription factor activity	Any process in which a virus starts, promotes, or enhances the activity of the host transcription factor NF-kappaB.	got7fsn_ti	activation of host NF-kappa-B by virus						bf	2012-10-11T16:04:31Z				VZ:841		biological_process											owl:Class	
GO:0018387	biolink:NamedThing	N-terminal peptidyl-amino acid deamination to pyruvic acid	The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.	got7fsn_ti												RESID:AA0127		biological_process											owl:Class	
GO:0048768	biolink:NamedThing	root hair cell tip growth	Localized growth of a plant root hair tip by extension of the cell wall.	got7fsn_ti	root hair tip growth													biological_process											owl:Class	
GO:0016170	biolink:NamedThing	interleukin-15 receptor binding	Binding to an interleukin-15 receptor.	got7fsn_ti	IL-15|interleukin-15 receptor ligand													molecular_function											owl:Class	
GO:0004739	biolink:NamedThing	pyruvate dehydrogenase (acetyl-transferring) activity	Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.	got7fsn_ti	pyruvate dehydrogenase complex activity|pyruvate dehydrogenase (lipoamide) activity|PDH|pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)|MtPDC (mitochondrial pyruvate dehydogenase complex) activity|pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity											EC:1.2.4.1|RHEA:19189		molecular_function											owl:Class	
GO:0008856	biolink:NamedThing	exodeoxyribonuclease X activity	Catalysis of the endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes.	got7fsn_ti	Escherichia coli endodeoxyribonuclease activity|deoxyribonuclease X activity|Escherichia coli endodeoxyribonuclease X activity											EC:3.1.11.-|MetaCyc:3.1.22.5-RXN		molecular_function											owl:Class	
GO:0044075	biolink:NamedThing	modulation by symbiont of host vacuole organization	Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism.	got7fsn_ti	modulation by symbiont of host vacuole biogenesis|modulation of host vacuole organization by symbiont|modulation by symbiont of host vacuole organisation|regulation by symbiont of host vacuole organization													biological_process											owl:Class	
GO:2000994	biolink:NamedThing	regulation of mannan catabolic process	Any process that modulates the frequency, rate or extent of mannan catabolic process.	got7fsn_ti	regulation of mannan catabolism|regulation of mannan degradation|regulation of mannan breakdown						tt	2011-08-08T03:19:03Z						biological_process											owl:Class	
GO:2000924	biolink:NamedThing	regulation of cellodextrin metabolic process	Any process that modulates the frequency, rate or extent of cellodextrin metabolic process.	got7fsn_ti	regulation of cellodextrin metabolism						tt	2011-08-01T12:39:52Z						biological_process											owl:Class	
GO:0019564	biolink:NamedThing	aerobic glycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen.	got7fsn_ti	aerobic glycerol catabolism|aerobic glycerol breakdown|aerobic glycerol fermentation|aerobic glycerol degradation										GO:0019565	MetaCyc:PWY0-381		biological_process											owl:Class	
GO:0019563	biolink:NamedThing	glycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	got7fsn_ti	glycerol catabolism|glycerol breakdown|glycerol degradation											MetaCyc:PWY-4261|MetaCyc:PWY0-381		biological_process											owl:Class	
GO:0032633	biolink:NamedThing	interleukin-4 production	The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-4 secretion|interleukin-4 biosynthetic process|IL-4 production										GO:0042224|GO:0072602|GO:0042097			biological_process											owl:Class	
GO:0019033	biolink:NamedThing	viral tegument	A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.	got7fsn_ti												Wikipedia:Viral_tegument		cellular_component											owl:Class	
GO:0006446	biolink:NamedThing	regulation of translational initiation	Any process that modulates the frequency, rate or extent of translational initiation.	got7fsn_ti														biological_process											owl:Class	
GO:0004636	biolink:NamedThing	phosphoribosyl-ATP diphosphatase activity	Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H(+).	got7fsn_ti	1-(5-phosphoribosyl)-ATP diphosphohydrolase activity|phosphoribosyladenosine triphosphate pyrophosphatase activity|phosphoribosyl-ATP pyrophosphatase activity											MetaCyc:HISTPRATPHYD-RXN|EC:3.6.1.31|KEGG_REACTION:R04035|RHEA:22828		molecular_function											owl:Class	
GO:0080070	biolink:NamedThing	8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate.	got7fsn_ti							dhl	2009-04-13T04:07:58Z				MetaCyc:RXNQT-4333		molecular_function											owl:Class	
GO:0050245	biolink:NamedThing	quercitrinase activity	Catalysis of the reaction: H(2)O + quercitrin = L-rhamnose + quercetin.	got7fsn_ti	quercitrin 3-L-rhamnohydrolase activity											MetaCyc:QUERCITRINASE-RXN|RHEA:17465|EC:3.2.1.66|KEGG_REACTION:R02436		molecular_function											owl:Class	
GO:0047142	biolink:NamedThing	enzyme-thiol transhydrogenase (glutathione-disulfide) activity	Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase.	got7fsn_ti	enzyme-thiol transhydrogenase (oxidized-glutathione) activity|glutathione-dependent thiol:disulfide oxidoreductase activity|thiol:disulphide oxidoreductase activity|xanthine-dehydrogenase:glutathione-disulfide S-oxidoreductase activity|xanthine-dehydrogenase:oxidized-glutathione S-oxidoreductase activity|thiol:disulfide oxidoreductase activity|[xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase activity|enzyme-thiol transhydrogenase (glutathione-disulphide) activity											MetaCyc:1.8.4.7-RXN|EC:1.8.4.7		molecular_function											owl:Class	
GO:0005513	biolink:NamedThing	detection of calcium ion	The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	calcium ion detection|detection of Ca2+ ion|Ca2+ ion detection|calcium ion sensing													biological_process											owl:Class	
GO:0051592	biolink:NamedThing	response to calcium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.	got7fsn_ti	response to Ca2+ ion													biological_process											owl:Class	
GO:0001517	biolink:NamedThing	N-acetylglucosamine 6-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.	got7fsn_ti	N-acetylglucosamine 6-O-sulphotransferase activity											Reactome:R-HSA-6786012|Reactome:R-HSA-2046222|Reactome:R-HSA-3656269		molecular_function											owl:Class	
GO:1990829	biolink:NamedThing	C-rich single-stranded DNA binding	Binding to C-rich, single-stranded DNA.	got7fsn_ti	C-rich ssDNA binding						sl	2015-08-20T16:05:12Z						molecular_function											owl:Class	
GO:0055123	biolink:NamedThing	digestive system development	The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0050836	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide.	got7fsn_ti												RESID:AA0357		biological_process											owl:Class	
GO:0004641	biolink:NamedThing	phosphoribosylformylglycinamidine cyclo-ligase activity	Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate.	got7fsn_ti	5'-aminoimidazole ribonucleotide synthetase activity|AIR synthetase activity|phosphoribosyl-aminoimidazole synthetase activity|2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)|2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)|AIRS activity|AIR synthase activity|phosphoribosylaminoimidazole synthetase activity											Reactome:R-HSA-73810|RHEA:23032|KEGG_REACTION:R04208|MetaCyc:AIRS-RXN|EC:6.3.3.1		molecular_function											owl:Class	
GO:0090323	biolink:NamedThing	prostaglandin secretion involved in immune response	The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		tb	2010-05-12T10:41:04Z						biological_process											owl:Class	
GO:0004616	biolink:NamedThing	phosphogluconate dehydrogenase (decarboxylating) activity	Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.	got7fsn_ti	phosphogluconic acid dehydrogenase activity|6-phospho-D-gluconate dehydrogenase activity|6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)|6-phosphogluconate dehydrogenase (decarboxylating)|6-phosphogluconic carboxylase activity|6PGD activity|6-phosphogluconic dehydrogenase activity											RHEA:10116|MetaCyc:6PGLUCONDEHYDROG-RXN|Reactome:R-HSA-71299|EC:1.1.1.44		molecular_function											owl:Class	
GO:0007138	biolink:NamedThing	meiotic anaphase II	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0006039	biolink:NamedThing	cell wall chitin catabolic process	The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.	got7fsn_ti	cell wall chitin breakdown|cell wall chitin degradation|cell wall chitin catabolism													biological_process											owl:Class	
GO:0018523	biolink:NamedThing	quinoline 2-oxidoreductase activity	Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.	got7fsn_ti	quinoline:acceptor 2-oxidoreductase (hydroxylating)											RHEA:17749|EC:1.3.99.17|UM-BBD_reactionID:r0045|MetaCyc:1.3.99.17-RXN		molecular_function											owl:Class	
GO:0103014	biolink:NamedThing	beta-keto ester reductase activity	Catalysis of the reaction: ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP = ethyl-2-methylacetoacetate + NADPH + H+.	got7fsn_ti												MetaCyc:RXN0-1941		molecular_function											owl:Class	
GO:0050570	biolink:NamedThing	4-hydroxythreonine-4-phosphate dehydrogenase activity	Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+.	got7fsn_ti	NAD+-dependent threonine 4-phosphate dehydrogenase activity|PdxA|L-threonine 4-phosphate dehydrogenase activity|4-(phosphohydroxy)-L-threonine dehydrogenase activity|NAD(+)-dependent threonine 4-phosphate dehydrogenase activity|4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase activity											MetaCyc:1.1.1.262-RXN|EC:1.1.1.262|RHEA:32275		molecular_function											owl:Class	
GO:0110057	biolink:NamedThing	regulation of blood vessel endothelial cell differentiation	Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation.	got7fsn_ti							kmv	2017-10-23T14:32:09Z						biological_process											owl:Class	
GO:0045601	biolink:NamedThing	regulation of endothelial cell differentiation	Any process that modulates the frequency, rate or extent of endothelial cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0070483	biolink:NamedThing	detection of hypoxia	The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	got7fsn_ti	detection of reduced oxygen levels													biological_process											owl:Class	
GO:0003032	biolink:NamedThing	detection of oxygen	The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0033196	biolink:NamedThing	tryparedoxin peroxidase activity	Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O.	got7fsn_ti	TXNPx activity											MetaCyc:1.11.1.15-RXN		molecular_function											owl:Class	
GO:0005522	biolink:NamedThing	profilin binding	Binding to profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.	got7fsn_ti														molecular_function											owl:Class	
GO:0043837	biolink:NamedThing	valine dehydrogenase (NAD) activity	Catalysis of the reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH.	got7fsn_ti	ValDH											EC:1.4.1.23|RHEA:30763		molecular_function											owl:Class	
GO:0048248	biolink:NamedThing	CXCR3 chemokine receptor binding	Binding to a CXCR3 chemokine receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0015818	biolink:NamedThing	isoleucine transport	The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-isoleucine transport													biological_process											owl:Class	
GO:0071619	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.	got7fsn_ti							mah	2010-02-09T02:37:02Z						biological_process											owl:Class	
GO:0022856	biolink:NamedThing	protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	sorbitol PTS transporter activity													molecular_function											owl:Class	
GO:0043851	biolink:NamedThing	methanol-specific methylcobalamin:coenzyme M methyltransferase activity	Catalysis of the reaction: a methylated methanol corrinoid protein + coenzyme M = a methanol corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.	got7fsn_ti	methyltransferase 2|methanol-specific methylcobalamin:CoM methyltransferase activity|MtaA|MT2|methanol-specific methylcobalamin: coenzyme M methyltransferase activity|MtaC protein: coenzyme M methyltransferase activity|MtaC protein:coenzyme M methyltransferase activity				This function is the second step in the pathway of methanogenesis from methanol.							MetaCyc:RXN-8096		molecular_function											owl:Class	
GO:0001867	biolink:NamedThing	complement activation, lectin pathway	Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.	got7fsn_ti	complement cascade, lectin pathway				Note that proteins such as mannose-binding lectin (MBL) and certain serum ficolins can activate the lectin complement pathway.									biological_process											owl:Class	
GO:0032248	biolink:NamedThing	positive regulation of purine nucleoside transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	up regulation of purine nucleoside transport|up-regulation of purine nucleoside transport|upregulation of purine nucleoside transport|stimulation of purine nucleoside transport|activation of purine nucleoside transport													biological_process											owl:Class	
GO:0032244	biolink:NamedThing	positive regulation of nucleoside transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	stimulation of nucleoside transport|activation of nucleoside transport|up regulation of nucleoside transport|upregulation of nucleoside transport|up-regulation of nucleoside transport													biological_process											owl:Class	
GO:0140696	biolink:NamedThing	(S)-2-hydroxyglutarate dehydrogenase activity	Catalysis of the reaction: (S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol.	got7fsn_ti	L-2-hydroxyglutarate dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/21957					pg	2021-08-11T14:16:32Z				RHEA:58664|EC:1.1.5.13		molecular_function											owl:Class	
GO:0106292	biolink:NamedThing	superoxide-generating NADPH oxidase activity	Catalysis of the reaction: NADPH + 2 O2 = H(+) + NADP(+) + 2 superoxide.	got7fsn_ti							hjd	2020-08-19T15:58:36Z				RHEA:63180		molecular_function											owl:Class	
GO:0016175	biolink:NamedThing	superoxide-generating NAD(P)H oxidase activity	Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-.	got7fsn_ti	cytochrome B-245											Reactome:R-HSA-5668731|Reactome:R-HSA-5218841|Reactome:R-HSA-5668718|Reactome:R-HSA-6789092|Reactome:R-HSA-1236967|Reactome:R-HSA-1497810|EC:1.6.3.-|Reactome:R-HSA-1222376|Reactome:R-HSA-6807557|Reactome:R-HSA-9673797|Reactome:R-HSA-5668629		molecular_function											owl:Class	
GO:0050501	biolink:NamedThing	hyaluronan synthase activity	Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP.	got7fsn_ti	HAS activity|alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity|seHAS|spHAS|alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity											RHEA:12528|EC:2.4.1.212|MetaCyc:2.4.1.212-RXN|Reactome:R-HSA-2160851		molecular_function											owl:Class	
GO:0090124	biolink:NamedThing	N-4 methylation of cytosine	The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule.	got7fsn_ti							tb	2009-12-07T02:40:38Z						biological_process											owl:Class	
GO:0102769	biolink:NamedThing	dihydroceramide glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine.	got7fsn_ti												EC:2.4.1.80|MetaCyc:RXN-7793		molecular_function											owl:Class	
GO:0097662	biolink:NamedThing	SCF-Das1 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae.	got7fsn_ti							pr	2014-10-06T10:26:27Z						cellular_component											owl:Class	
GO:0002124	biolink:NamedThing	territorial aggressive behavior	Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.	got7fsn_ti	territorial aggression													biological_process											owl:Class	
GO:0047574	biolink:NamedThing	4-acetamidobutyryl-CoA deacetylase activity	Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H(2)O = 4-aminobutanoyl-CoA + acetate.	got7fsn_ti	4-acetamidobutanoyl-CoA amidohydrolase activity|deacetylase-thiolesterase activity|aminobutyryl-CoA thiolesterase activity											EC:3.5.1.51|KEGG_REACTION:R04056|MetaCyc:4-ACETAMIDOBUTYRYL-COA-DEACETYLASE-RXN|RHEA:22928		molecular_function											owl:Class	
GO:0102585	biolink:NamedThing	cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity	Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + malonyl-CoA + H+ <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + coenzyme A.	got7fsn_ti												MetaCyc:RXN-15331		molecular_function											owl:Class	
GO:0045244	biolink:NamedThing	succinate-CoA ligase complex (GDP-forming)	A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP.	got7fsn_ti	succinyl-CoA synthetase, GDP-forming										GO:0008325|GO:0045245			cellular_component											owl:Class	
GO:0080066	biolink:NamedThing	3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 3-methylthiopropyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 3-methylthiopropyl-glucosinolate + adenosine 3',5'-bisphosphate.	got7fsn_ti							dhl	2009-04-13T04:04:08Z				MetaCyc:RXN-2209		molecular_function											owl:Class	
GO:0021739	biolink:NamedThing	mesencephalic trigeminal nucleus development	The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0044606	biolink:NamedThing	phosphocholine hydrolase activity	Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate.	got7fsn_ti							jl	2012-05-24T04:46:44Z						molecular_function											owl:Class	
GO:0050396	biolink:NamedThing	vomifoliol 4'-dehydrogenase activity	Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH.	got7fsn_ti	vomifoliol:NAD+ 4'-oxidoreductase activity											RHEA:22804|EC:1.1.1.221|KEGG_REACTION:R04412|MetaCyc:VOMIFOLIOL-4-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0071029	biolink:NamedThing	nuclear ncRNA surveillance	The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus.	got7fsn_ti	nuclear aberrant ncRNA catabolic process|nuclear ncRNA quality control						krc	2009-07-28T04:22:31Z						biological_process											owl:Class	
GO:0014856	biolink:NamedThing	skeletal muscle cell proliferation	The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
GO:1990986	biolink:NamedThing	DNA recombinase disassembly	The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases).	got7fsn_ti	Rad51 nucleoprotein filament disassembly						pg	2016-11-18T13:13:56Z						biological_process											owl:Class	
GO:0060816	biolink:NamedThing	random inactivation of X chromosome	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.	got7fsn_ti							dph	2009-08-11T10:47:30Z						biological_process											owl:Class	
GO:0102754	biolink:NamedThing	chlorophyllide-b:phytyl-diphosphate phytyltransferase activity	Catalysis of the reaction: H+ + chlorophyllide b + (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate <=> chlorophyll b + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-7674		molecular_function											owl:Class	
GO:1900771	biolink:NamedThing	fumitremorgin B catabolic process	The chemical reactions and pathways resulting in the breakdown of fumitremorgin B.	got7fsn_ti	fumitremorgin B catabolism|Lanosulin catabolism|Lanosulin catabolic process|fumitremorgin B degradation|Lanosulin breakdown|Lanosulin degradation|fumitremorgin B breakdown						di	2012-06-04T09:25:43Z						biological_process											owl:Class	
GO:1900767	biolink:NamedThing	fonsecin metabolic process	The chemical reactions and pathways involving fonsecin.	got7fsn_ti	fonsecin metabolism						di	2012-06-04T09:21:14Z						biological_process											owl:Class	
GO:0002281	biolink:NamedThing	macrophage activation involved in immune response	A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	macrophage activation during immune response|macrophage polarization involved in immune response													biological_process											owl:Class	
GO:0033787	biolink:NamedThing	cyanocobalamin reductase (cyanide-eliminating) activity	Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH.	got7fsn_ti	NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity|cyanocobalamin reductase activity|cyanocobalamin reductase (NADPH; CN-eliminating) activity|cyanocobalamin reductase (NADPH, cyanide-eliminating) activity|NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity|cob(I)alamin, cyanide:NADP+ oxidoreductase activity				Formerly EC:1.6.99.12.							EC:1.16.1.6|KEGG_REACTION:R02999|RHEA:16113|Reactome:R-HSA-3149519|MetaCyc:1.6.99.12-RXN		molecular_function											owl:Class	
GO:0047926	biolink:NamedThing	geranyl-diphosphate cyclase activity	Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate.	got7fsn_ti	bornyl pyrophosphate synthetase activity|(+)-bornylpyrophosphate cyclase activity|bornyl pyrophosphate synthase activity|(+)-bornyl-diphosphate lyase (decyclizing)|bornyl diphosphate synthase activity											MetaCyc:GERANYL-DIPHOSPHATE-CYCLASE-RXN|RHEA:18209|EC:5.5.1.8|KEGG_REACTION:R02007		molecular_function											owl:Class	
GO:0050401	biolink:NamedThing	xylonate dehydratase activity	Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O.	got7fsn_ti	D-xylo-aldonate dehydratase activity|D-xylonate hydro-lyase activity|D-xylonate hydro-lyase (2-dehydro-3-deoxy-D-xylonate-forming)|D-xylonate dehydratase activity											MetaCyc:XYLONATE-DEHYDRATASE-RXN|RHEA:19157|EC:4.2.1.82|KEGG_REACTION:R02429		molecular_function											owl:Class	
GO:0033800	biolink:NamedThing	isoflavone 7-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.	got7fsn_ti	S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase activity											MetaCyc:RXN-6241|EC:2.1.1.150|RHEA:17933		molecular_function											owl:Class	
GO:0010085	biolink:NamedThing	polarity specification of proximal/distal axis	Any process resulting in the establishment of polarity along the proximal/distal axis.	got7fsn_ti														biological_process											owl:Class	
GO:0008867	biolink:NamedThing	galactarate dehydratase activity	Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.	got7fsn_ti	D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)|D-galactarate hydro-lyase activity											RHEA:16005|MetaCyc:GALACTARDEHYDRA-RXN|EC:4.2.1.42|KEGG_REACTION:R05608		molecular_function											owl:Class	
GO:1990478	biolink:NamedThing	response to ultrasound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.	got7fsn_ti							sl	2014-09-09T22:11:32Z						biological_process											owl:Class	
GO:0015048	biolink:NamedThing	phthalate dioxygenase reductase activity	Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems.	got7fsn_ti														molecular_function											owl:Class	
GO:0016278	biolink:NamedThing	lysine N-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue.	got7fsn_ti												Reactome:R-HSA-6805755|Reactome:R-HSA-6805740|Reactome:R-HSA-3222237|Reactome:R-HSA-6805730		molecular_function											owl:Class	
GO:0042006	biolink:NamedThing	masculinization of hermaphroditic germ-line	The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.	got7fsn_ti														biological_process											owl:Class	
GO:0040021	biolink:NamedThing	hermaphrodite germ-line sex determination	The determination of sex and sexual phenotype in the germ line of a hermaphrodite.	got7fsn_ti											GO:0042005			biological_process											owl:Class	
GO:0102325	biolink:NamedThing	2,2',3-trihydroxybiphenyl monooxygenase activity	Catalysis of the reaction: biphenyl-2,2',3-triol + O2 + NADH + H+ <=> 2,2',3,3'-tetrahydroxybiphenyl + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-13169|RHEA:63516		molecular_function											owl:Class	
GO:0004820	biolink:NamedThing	glycine-tRNA ligase activity	Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).	got7fsn_ti	glycyl-transfer ribonucleate synthetase activity|glycine:tRNAGly ligase (AMP-forming) activity|glycyl-transfer RNA synthetase activity|glycyl-tRNA synthetase activity|glycyl-transfer ribonucleic acid synthetase activity|glycyl translase activity											MetaCyc:GLYCINE--TRNA-LIGASE-RXN|RHEA:16013|Reactome:R-HSA-380240|Reactome:R-HSA-380048|EC:6.1.1.14		molecular_function											owl:Class	
GO:0004595	biolink:NamedThing	pantetheine-phosphate adenylyltransferase activity	Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.	got7fsn_ti	phosphopantetheine adenylyltransferase activity|ATP:pantetheine-phosphate adenylyltransferase activity|3'-dephospho-CoA pyrophosphorylase activity|ATP:pantetheine-4'-phosphate adenylyltransferase activity|dephospho-coenzyme A pyrophosphorylase activity|pantetheine phosphate adenylyltransferase activity|dephospho-CoA pyrophosphorylase activity|dephospho-CoA diphosphorylase activity|PPAT activity											MetaCyc:PANTEPADENYLYLTRAN-RXN|RHEA:19801|EC:2.7.7.3|KEGG_REACTION:R03035|Reactome:R-HSA-196754		molecular_function											owl:Class	
GO:0106327	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP.	got7fsn_ti							hjd	2020-09-30T13:44:42Z				EC:2.4.1.147|RHEA:46880		molecular_function											owl:Class	
GO:0034170	biolink:NamedThing	toll-like receptor 11 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 11.	got7fsn_ti	TLR11 signaling pathway|toll-like receptor 11 signalling pathway													biological_process											owl:Class	
GO:0090328	biolink:NamedThing	regulation of olfactory learning	Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.	got7fsn_ti							tb	2010-05-14T10:37:22Z						biological_process											owl:Class	
GO:0061348	biolink:NamedThing	planar cell polarity pathway involved in ventricular septum morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.	got7fsn_ti							dph	2010-10-01T10:47:49Z						biological_process											owl:Class	
GO:1990052	biolink:NamedThing	ER to chloroplast lipid transport	The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast.	got7fsn_ti	ER to chloroplast lipid trafficking|endoplasmic reticulum to chloroplast lipid transport						tb	2013-02-22T00:05:23Z						biological_process											owl:Class	
GO:0030776	biolink:NamedThing	(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline.	got7fsn_ti	S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity|norreticuline N-methyltransferase activity|(RS)-tetrahydrobenzylisoquinoline N-methyltransferase activity											EC:2.1.1.115|RHEA:13005|MetaCyc:2.1.1.115-RXN		molecular_function											owl:Class	
GO:0050957	biolink:NamedThing	equilibrioception	The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.	got7fsn_ti	sensory perception of orientation with respect to gravity											Wikipedia:Equilibrioception		biological_process											owl:Class	
GO:0098625	biolink:NamedThing	methylselenol reductase activity	Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O.	got7fsn_ti												Reactome:R-HSA-5263614		molecular_function											owl:Class	
GO:0047164	biolink:NamedThing	isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity	Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.	got7fsn_ti	malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase activity|malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase activity|malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase activity|flavone/flavonol 7-O-beta-D-glucoside malonyltransferase activity|flavone (flavonol) 7-O-glycoside malonyltransferase activity|malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase activity|MAT-7											EC:2.3.1.115|RHEA:15581|MetaCyc:2.3.1.115-RXN		molecular_function											owl:Class	
GO:0031271	biolink:NamedThing	lateral pseudopodium assembly	The extension of a pseudopodium from the lateral area of a cell.	got7fsn_ti	lateral pseudopodium formation													biological_process											owl:Class	
GO:0051897	biolink:NamedThing	positive regulation of protein kinase B signaling	Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.	got7fsn_ti	positive regulation of protein kinase B signalling cascade|activation of protein kinase B signaling cascade|positive regulation of protein kinase B signaling cascade|up-regulation of protein kinase B signaling cascade|positive regulation of PKB signaling cascade|positive regulation of PKB signalling cascade|stimulation of protein kinase B signaling cascade|positive regulation of AKT signalling cascade|positive regulation of AKT signaling cascade|upregulation of protein kinase B signaling cascade|up regulation of protein kinase B signaling cascade													biological_process											owl:Class	
GO:0033407	biolink:NamedThing	UCA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UCA codon.	got7fsn_ti	serine tRNA|TCA codon-amino acid adaptor activity				Note that in the standard genetic code, TCA codes for serine.									molecular_function											owl:Class	
GO:0033809	biolink:NamedThing	anthocyanin 6''-O-malonyltransferase activity	Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).	got7fsn_ti	Dv3MaT|3MaT|malonyl-coenzymeA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity											RHEA:16025|MetaCyc:2.3.1.171-RXN|EC:2.3.1.171		molecular_function											owl:Class	
GO:0102814	biolink:NamedThing	caffeoyl-CoA:delphinidin-3,5,3'-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: delphinidin 3,3',5-tri-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + coenzyme A.	got7fsn_ti												MetaCyc:RXN-8232		molecular_function											owl:Class	
GO:0048460	biolink:NamedThing	flower formation	The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti											GO:0048410			biological_process											owl:Class	
GO:0051327	biolink:NamedThing	meiotic M phase	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.	got7fsn_ti	M phase of meiotic cell cycle				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0060416	biolink:NamedThing	response to growth hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.	got7fsn_ti	response to growth hormone stimulus													biological_process											owl:Class	
GO:0047989	biolink:NamedThing	hydroxybutyrate-dimer hydrolase activity	Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H(2)O = 2 (R)-3-hydroxybutanoate + H(+).	got7fsn_ti	(R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase activity|D-(-)-3-hydroxybutyrate-dimer hydrolase activity											EC:3.1.1.22|MetaCyc:HYDROXYBUTYRATE-DIMER-HYDROLASE-RXN|RHEA:10172|KEGG_REACTION:R00048		molecular_function											owl:Class	
GO:0106349	biolink:NamedThing	snRNA methylation	The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.	got7fsn_ti							hjd	2020-12-18T15:55:19Z						biological_process											owl:Class	
GO:0018698	biolink:NamedThing	vinyl chloride reductive dehalogenase activity	Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene.	got7fsn_ti												UM-BBD_reactionID:r0352|EC:1.97.1.-|MetaCyc:VCREDCHLOR-RXN		molecular_function											owl:Class	
GO:0018122	biolink:NamedThing	peptidyl-asparagine ADP-ribosylation	The transfer, from NAD, of ADP-ribose to peptidyl-asparagine to form peptidyl-N4-(ADP-ribosyl)-L-asparagine.	got7fsn_ti												RESID:AA0231		biological_process											owl:Class	
GO:0050346	biolink:NamedThing	trans-L-3-hydroxyproline dehydratase activity	Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H(2)O + H(+).	got7fsn_ti	trans-L-3-hydroxyproline hydro-lyase activity|trans-L-3-hydroxyproline hydro-lyase (Delta1-pyrroline 2-carboxylate-forming)											MetaCyc:TRANS-L-3-HYDROXYPROLINE-DEHYDRATASE-RXN|RHEA:10320|KEGG_REACTION:R04374|EC:4.2.1.77		molecular_function											owl:Class	
GO:0140090	biolink:NamedThing	membrane curvature sensor activity	Preferential binding of proteins on curved membranes. The binding to curved membranes by insertion (aka wedging) to curved membranes is mediated by both the hydrophobic and hydrophilic faces of the helix of membrane curvature sensing (MCS) proteins.	got7fsn_ti							pg	2017-08-19T20:37:54Z						molecular_function											owl:Class	
GO:0008289	biolink:NamedThing	lipid binding	Binding to a lipid.	got7fsn_ti														molecular_function											owl:Class	
GO:0034907	biolink:NamedThing	acetanilide 1,2-dioxygenase activity	Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide.	got7fsn_ti												UM-BBD_reactionID:r0723|EC:1.14.12.-		molecular_function											owl:Class	
GO:0032405	biolink:NamedThing	MutLalpha complex binding	Binding to a MutLalpha mismatch repair complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0039672	biolink:NamedThing	suppression by virus of host natural killer cell activation	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host.	got7fsn_ti	suppression by virus of host NK-cell activation						bf	2013-09-25T11:08:19Z						biological_process											owl:Class	
GO:0032815	biolink:NamedThing	negative regulation of natural killer cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.	got7fsn_ti	downregulation of natural killer cell activation|down regulation of natural killer cell activation|inhibition of natural killer cell activation|down-regulation of natural killer cell activation|negative regulation of NK cell activation													biological_process											owl:Class	
GO:0006349	biolink:NamedThing	regulation of gene expression by genetic imprinting	Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself.	got7fsn_ti	regulation of gene expression by DNA imprinting											Wikipedia:Genomic_imprinting		biological_process											owl:Class	
GO:0046657	biolink:NamedThing	folic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid.	got7fsn_ti	vitamin B9 catabolism|folic acid breakdown|folate catabolism|folic acid catabolism|folic acid degradation|vitamin M catabolic process|vitamin B9 catabolic process|folate catabolic process|vitamin M catabolism													biological_process											owl:Class	
GO:0031413	biolink:NamedThing	regulation of buoyancy	Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases.	got7fsn_ti	buoyancy regulation													biological_process											owl:Class	
GO:0031043	biolink:NamedThing	O-glycan processing, core 7	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc.	got7fsn_ti														biological_process											owl:Class	
GO:0098931	biolink:NamedThing	virion attachment to host cell flagellum	The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface.	got7fsn_ti												VZ:3949		biological_process											owl:Class	
GO:0050933	biolink:NamedThing	early stripe melanocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).	got7fsn_ti	early stripe melanocyte cell differentiation|early stripe melanophore differentiation													biological_process											owl:Class	
GO:0061243	biolink:NamedThing	mesonephric renal vesicle morphogenesis	The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.	got7fsn_ti							dph	2010-08-19T03:20:21Z						biological_process											owl:Class	
GO:0004373	biolink:NamedThing	glycogen (starch) synthase activity	Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1).	got7fsn_ti	UDP-glycogen synthase activity|UDP-glucose-glycogen glucosyltransferase activity|UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|uridine diphosphoglucose-glycogen glucosyltransferase activity|UDPG-glycogen synthetase activity|glycogen (starch) synthetase activity|UDPG-glycogen transglucosylase activity|UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity											EC:2.4.1.11|Reactome:R-HSA-3858506|RHEA:18549|MetaCyc:2.4.1.11-RXN|Reactome:R-HSA-3828061|Reactome:R-HSA-3322001|Reactome:R-HSA-3322041|Reactome:R-HSA-3322009		molecular_function											owl:Class	
GO:0090068	biolink:NamedThing	positive regulation of cell cycle process	Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.	got7fsn_ti							tb	2009-09-09T11:39:52Z						biological_process											owl:Class	
GO:0047741	biolink:NamedThing	cetraxate benzylesterase activity	Catalysis of the reaction: benzyl cetraxate + H(2)O = benzyl alcohol + cetraxate + H(+).	got7fsn_ti	cetraxate-benzyl-ester benzylhydrolase activity											MetaCyc:CETRAXATE-BENZYLESTERASE-RXN|RHEA:23460|KEGG_REACTION:R03612|EC:3.1.1.70		molecular_function											owl:Class	
GO:0018580	biolink:NamedThing	nitronate monooxygenase activity	Catalysis of the reaction: ethylnitronate + O(2) = acetaldehyde + nitrite.	got7fsn_ti	2-nitropropane dioxygenase activity|nitronate:oxygen 2-oxidoreductase (nitrite-forming) activity				Where non-covalently bound FMN is used as the cofactor, see instead 'nitronate monooxygenase (FMN-linked) activity ; GO:0036434'.							MetaCyc:2-NITROPROPANE-DIOXYGENASE-RXN|RHEA:28767|EC:1.13.12.16		molecular_function											owl:Class	
GO:0047822	biolink:NamedThing	hypotaurine dehydrogenase activity	Catalysis of the reaction: H(2)O + hypotaurine + NAD(+) = H(+) + NADH + taurine.	got7fsn_ti	hypotaurine:NAD+ oxidoreductase activity											MetaCyc:HYPOTAURINE-DEHYDROGENASE-RXN|KEGG_REACTION:R01681|RHEA:17385|Reactome:R-HSA-1655453|EC:1.8.1.3		molecular_function											owl:Class	
GO:0051889	biolink:NamedThing	negative regulation of timing of exogen	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.	got7fsn_ti	downregulation of exogen|negative regulation of exogen|inhibition of exogen|down-regulation of exogen|down regulation of exogen													biological_process											owl:Class	
GO:0035573	biolink:NamedThing	N-terminal peptidyl-serine trimethylation	The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.	got7fsn_ti							bf	2010-08-06T02:00:42Z						biological_process											owl:Class	
GO:0018672	biolink:NamedThing	anthranilate 3-monooxygenase (deaminating) activity	Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+).	got7fsn_ti	anthranilate hydroxylase activity|anthranilate hydroxylase (deaminating) activity|anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating)|anthranilate 2,3-dioxygenase (deaminating)|anthranilate 2,3-hydroxylase (deaminating) activity											EC:1.14.13.35|RHEA:21236|UM-BBD_reactionID:r0578|KEGG_REACTION:R00980|MetaCyc:1.14.13.35-RXN		molecular_function											owl:Class	
GO:0048524	biolink:NamedThing	positive regulation of viral process	Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant.	got7fsn_ti	positive regulation of viral reproduction|up-regulation of viral life cycle|activation of viral life cycle|up regulation of viral life cycle|positive regulation of viral life cycle|upregulation of viral life cycle|stimulation of viral life cycle													biological_process											owl:Class	
GO:0031777	biolink:NamedThing	type 1 melanin-concentrating hormone receptor binding	Binding to a type 1 melanin-concentrating hormone receptor.	got7fsn_ti	type 1 melanin-concentrating hormone receptor ligand													molecular_function											owl:Class	
GO:0045819	biolink:NamedThing	positive regulation of glycogen catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.	got7fsn_ti	upregulation of glycogen catabolic process|stimulation of glycogen catabolic process|positive regulation of glycogen breakdown|positive regulation of glycogenolysis|up-regulation of glycogen catabolic process|positive regulation of glycogen degradation|up regulation of glycogen catabolic process|positive regulation of glycogen catabolism|activation of glycogen catabolic process													biological_process											owl:Class	
GO:0030751	biolink:NamedThing	licodione 2'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:licodione 2'-O-methyltransferase activity											RHEA:18521|KEGG_REACTION:R03623|EC:2.1.1.65|MetaCyc:LICODIONE-2-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0035402	biolink:NamedThing	histone kinase activity (H3-T11 specific)	Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3.	got7fsn_ti	histone-threonine kinase activity (H3-T11 specific)|histone threonine kinase activity (H3-T11 specific)						bf	2010-03-24T10:04:40Z						molecular_function											owl:Class	
GO:0052765	biolink:NamedThing	reduced coenzyme F420 oxidase activity	Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O.	got7fsn_ti	F420H2:oxygen oxidoreductase activity|coenzyme F420H2 oxidase activity|F420H2 oxidase activity						ai	2011-09-29T04:33:54Z						molecular_function											owl:Class	
GO:0031141	biolink:NamedThing	induction of conjugation upon carbon starvation	The process in which a cell initiates conjugation with cellular fusion upon carbon starvation.	got7fsn_ti														biological_process											owl:Class	
GO:0033754	biolink:NamedThing	indoleamine 2,3-dioxygenase activity	Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.	got7fsn_ti	IDO|D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity|tryptophan pyrrolase activity											MetaCyc:RXN-8665|EC:1.13.11.52|RHEA:14189|MetaCyc:RXN-8664		molecular_function											owl:Class	
GO:0010043	biolink:NamedThing	response to zinc ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.	got7fsn_ti	response to zinc													biological_process											owl:Class	
GO:0097449	biolink:NamedThing	astrocyte projection	A prolongation or process extending from the soma of an astrocyte and wrapping around neurons.	got7fsn_ti	astrocyte process|vellous process|peripheral astrocyte process						pr	2012-12-17T13:29:55Z				NIF_Subcellular:sao1630537580		cellular_component											owl:Class	
GO:0050623	biolink:NamedThing	berberine reductase activity	Catalysis of the reaction: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH.	got7fsn_ti	(R)-canadine synthase activity|(R)-tetrahydroberberine:NADP+ oxidoreductase activity											KEGG_REACTION:R07169|MetaCyc:1.5.1.31-RXN|RHEA:21268|EC:1.5.1.31		molecular_function											owl:Class	
GO:0047670	biolink:NamedThing	anhydrotetracycline monooxygenase activity	Catalysis of the reaction: anhydrotetracycline + H(+) + NADPH + O(2) = 12-dehydrotetracycline + H(2)O + NADP(+).	got7fsn_ti	anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)|anhydrotetracycline oxygenase activity|ATC oxygenase activity											KEGG_REACTION:R04060|EC:1.14.13.38|RHEA:11976|MetaCyc:ANHYDROTETRACYCLINE-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0039644	biolink:NamedThing	suppression by virus of host NF-kappaB transcription factor activity	Any process in which a virus stops, prevents, or reduces the activity of host NF-kappaB activity.	got7fsn_ti	inhibition of host NF-kappa-B by virus						bf	2012-10-09T15:04:27Z				VZ:695		biological_process											owl:Class	
GO:0039653	biolink:NamedThing	suppression by virus of host transcription	Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors.	got7fsn_ti	host transcription shutoff by virus|suppression by virus of host DNA-dependent transcription						bf	2012-10-11T16:11:17Z				VZ:1577		biological_process											owl:Class	
GO:0050522	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors	Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP.	got7fsn_ti												EC:1.20.98.-		molecular_function											owl:Class	
GO:0017192	biolink:NamedThing	N-terminal peptidyl-glutamine acetylation	The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.	got7fsn_ti												RESID:AA0045		biological_process											owl:Class	
GO:0010894	biolink:NamedThing	negative regulation of steroid biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	got7fsn_ti														biological_process											owl:Class	
GO:0042868	biolink:NamedThing	antisense RNA metabolic process	The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis.	got7fsn_ti	antisense RNA metabolism													biological_process											owl:Class	
GO:1990206	biolink:NamedThing	jasmonyl-Ile conjugate hydrolase activity	Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine.	got7fsn_ti	JA-Ile hydrolase						tb	2013-10-07T18:37:49Z						molecular_function											owl:Class	
GO:0102641	biolink:NamedThing	(R)-lactaldehyde dehydrogenase activity	Catalysis of the reaction: (R)-propane-1,2-diol + NADP <=> (R)-lactaldehyde + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-15743		molecular_function											owl:Class	
GO:0030517	biolink:NamedThing	negative regulation of axon extension	Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.	got7fsn_ti	downregulation of axon extension|down regulation of axon extension|down-regulation of axon extension|inhibition of axon extension													biological_process											owl:Class	
GO:0000344	biolink:NamedThing	plastid-encoded plastid RNA polymerase complex B	A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation.	got7fsn_ti	PEP-B													cellular_component											owl:Class	
GO:0120056	biolink:NamedThing	large intestinal transit	Migration of ingested material along the length of the large intestine.	got7fsn_ti	large intestine transit|colonic transit|large bowel transit|colon transit						krc	2017-06-13T20:52:01Z						biological_process											owl:Class	
GO:0047241	biolink:NamedThing	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity	Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP.	got7fsn_ti	UDP-N-acetyl-beta-D-mannosaminouronate:lipopolysaccharide N-acetyl-beta-D-mannosaminouronosyltransferase activity|LPS N-acetylmannosaminouronosyltransferase activity|ManNAcA transferase activity|uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase activity											EC:2.4.1.180|RHEA:28366|MetaCyc:2.4.1.180-RXN		molecular_function											owl:Class	
GO:0047474	biolink:NamedThing	long-chain fatty acid luciferin component ligase activity	Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain-fatty-acid luciferin component ligase activity|long-chain-fatty-acid-luciferin-component ligase activity|acyl-protein synthetase activity|long-chain-fatty-acid:protein ligase (AMP-forming)											EC:6.2.1.19|MetaCyc:6.2.1.19-RXN|RHEA:20101		molecular_function											owl:Class	
GO:0006893	biolink:NamedThing	Golgi to plasma membrane transport	The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.	got7fsn_ti	Golgi to plasma membrane vesicle-mediated transport													biological_process											owl:Class	
GO:0019380	biolink:NamedThing	3-phenylpropionate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid.	got7fsn_ti	3-phenylpropionate breakdown|3-phenylpropionate degradation|3-phenylpropionate catabolism											MetaCyc:HCAMHPDEG-PWY|MetaCyc:P281-PWY		biological_process											owl:Class	
GO:0061667	biolink:NamedThing	URM1 ligase activity	Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S --> X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate.	got7fsn_ti	E3						dph	2014-11-06T14:04:43Z						molecular_function											owl:Class	
GO:0042294	biolink:NamedThing	URM1 transferase activity	Catalysis of the transfer of URM1 from one protein to another via the reaction X-URM1 + Y --> Y-URM1 + X, where both X-URM1 and Y-URM1 are covalent linkages.	got7fsn_ti														molecular_function											owl:Class	
GO:0080132	biolink:NamedThing	fatty acid alpha-hydroxylase activity	Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.	got7fsn_ti	fatty acid 2-hydroxylase						dhl	2009-05-06T04:43:36Z				Reactome:R-HSA-5693761		molecular_function											owl:Class	
GO:0110015	biolink:NamedThing	positive regulation of elastin catabolic process	Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.	got7fsn_ti							kmv	2017-05-10T14:54:12Z						biological_process											owl:Class	
GO:0060310	biolink:NamedThing	regulation of elastin catabolic process	Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.	got7fsn_ti	regulation of elastin catabolism|regulation of elastin degradation|regulation of elastin breakdown													biological_process											owl:Class	
GO:0045986	biolink:NamedThing	negative regulation of smooth muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.	got7fsn_ti	down-regulation of smooth muscle contraction|down regulation of smooth muscle contraction|inhibition of smooth muscle contraction|downregulation of smooth muscle contraction|smooth muscle relaxation													biological_process											owl:Class	
GO:0102491	biolink:NamedThing	dGTP phosphohydrolase activity	Catalysis of the reaction: dGTP + 2 H2O = dGMP + 2 hydrogenphosphate + 2 H+.	got7fsn_ti												MetaCyc:RXN-14208|EC:3.6.1.5		molecular_function											owl:Class	
GO:0006382	biolink:NamedThing	adenosine to inosine editing	The conversion of an adenosine residue to inosine in an RNA molecule by deamination.	got7fsn_ti														biological_process											owl:Class	
GO:0002255	biolink:NamedThing	tissue kallikrein-kinin cascade	A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.	got7fsn_ti	glandular kallikrein-kinin cascade													biological_process											owl:Class	
GO:0052912	biolink:NamedThing	23S rRNA (guanine(748)-N(1))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine.	got7fsn_ti	23S rRNA m(1)G(748) methyltransferase activity											KEGG_REACTION:R07233|EC:2.1.1.188|MetaCyc:RXN-11599|RHEA:42904		molecular_function											owl:Class	
GO:0098760	biolink:NamedThing	response to interleukin-7	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.	got7fsn_ti	response to IL-7													biological_process											owl:Class	
GO:0106364	biolink:NamedThing	4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity	4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].	got7fsn_ti							hjd	2021-02-09T15:52:26Z				RHEA:20361		molecular_function											owl:Class	
GO:0046224	biolink:NamedThing	bacteriocin metabolic process	The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.	got7fsn_ti	bacteriocin metabolism													biological_process											owl:Class	
GO:0051975	biolink:NamedThing	lysine biosynthetic process via alpha-aminoadipate and saccharopine	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine.	got7fsn_ti	lysine biosynthesis via aminoadipic acid and saccharopine|lysine biosynthetic process via aminoadipic acid and saccharopine											MetaCyc:LYSINE-AMINOAD-PWY		biological_process											owl:Class	
GO:0097208	biolink:NamedThing	alveolar lamellar body	A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.	got7fsn_ti							pr	2012-01-04T02:33:04Z						cellular_component											owl:Class	
GO:0005832	biolink:NamedThing	chaperonin-containing T-complex	A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.	got7fsn_ti	CCT particle|TriC													cellular_component											owl:Class	
GO:2000642	biolink:NamedThing	negative regulation of early endosome to late endosome transport	Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport.	got7fsn_ti							vk	2011-04-21T11:20:06Z						biological_process											owl:Class	
GO:0047535	biolink:NamedThing	2-alkyn-1-ol dehydrogenase activity	Catalysis of the reaction: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH.	got7fsn_ti	2-butyne-1,4-diol:NAD+ 1-oxidoreductase activity											KEGG_REACTION:R03963|EC:1.1.1.165|MetaCyc:2-ALKYN-1-OL-DEHYDROGENASE-RXN|RHEA:19101		molecular_function											owl:Class	
GO:0080012	biolink:NamedThing	trihydroxyferuloyl spermidine O-methyltransferase activity	Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+.	got7fsn_ti	N1,N5,N10-tris-(5-hydroxyferuloyl)spermidine O-methyltransferase activity											MetaCyc:RXN-11263		molecular_function											owl:Class	
GO:0098605	biolink:NamedThing	selenocystathionine beta-synthase activity	Catalysis of the reaction: L-Serine + Selenohomocysteine => L-Selenocystathionine + H2O.	got7fsn_ti							dos	2014-04-16T11:07:50Z				Reactome:R-HSA-2408559		molecular_function											owl:Class	
GO:0015690	biolink:NamedThing	aluminum cation transport	The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	aluminum transport|aluminium ion transport|aluminum ion transport|aluminium transport													biological_process											owl:Class	
GO:0006812	biolink:NamedThing	cation transport	The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	di-, tri-valent inorganic cation transport|trivalent inorganic cation transport										GO:0006819|GO:0015674|GO:0072512			biological_process											owl:Class	
GO:0018803	biolink:NamedThing	4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity	Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate.	got7fsn_ti	2'-carboxybenzalpyruvate aldolase activity|(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)|trans-2'-carboxybenzalpyruvate hydratase-aldolase activity|(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity|(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity											MetaCyc:4.1.2.34-RXN|UM-BBD_reactionID:r0487|RHEA:16453|EC:4.1.2.34		molecular_function											owl:Class	
GO:0061689	biolink:NamedThing	tricellular tight junction	An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet.	got7fsn_ti							dph	2015-04-12T10:34:19Z						cellular_component											owl:Class	
GO:0047354	biolink:NamedThing	sphingosine cholinephosphotransferase activity	Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine.	got7fsn_ti	sphingosine choline phosphotransferase activity|CDP-choline-sphingosine cholinephosphotransferase activity|CDP-choline:sphingosine cholinephosphotransferase activity|cytidine diphosphocholine-sphingosine cholinephosphotransferase activity|phosphorylcholine-sphingosine transferase activity											KEGG_REACTION:R01929|MetaCyc:2.7.8.10-RXN|EC:2.7.8.10|RHEA:21224		molecular_function											owl:Class	
GO:0051451	biolink:NamedThing	myoblast migration	The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0075222	biolink:NamedThing	sporangium germination	The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores.	got7fsn_ti	sporangium germination on or near host|symbiont sporangium germination on or near host|direct germination on or near host|germination of symbiont sporangium on or near host													biological_process											owl:Class	
GO:0005114	biolink:NamedThing	type II transforming growth factor beta receptor binding	Binding to a type II transforming growth factor beta receptor.	got7fsn_ti	punt ligand|type II TGF-beta binding|transforming growth factor beta ligand binding to type II receptor|transforming growth factor beta receptor type II binding|TGF-beta type II binding|punt binding													molecular_function											owl:Class	
GO:0035028	biolink:NamedThing	leading edge cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:1990577	biolink:NamedThing	C-terminal protein demethylation	The removal of a methyl group from the C-terminal amino acid of a protein.	got7fsn_ti							mcc	2014-12-08T20:55:17Z						biological_process											owl:Class	
GO:0000177	biolink:NamedThing	cytoplasmic exosome (RNase complex)	A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.	got7fsn_ti	prokaryotic exosome multienzyme ribonuclease complex|cytoplasmic exosome (ribonuclease complex)|cytoplasmic exosome multienzyme ribonuclease complex													cellular_component											owl:Class	
GO:0044653	biolink:NamedThing	dextrin alpha-glucosidase activity	Catalysis of the reaction: dextrin + H2O = alpha-D-glucose.	got7fsn_ti							jl	2012-07-23T02:01:12Z				EC:3.2.1.-		molecular_function											owl:Class	
GO:0034784	biolink:NamedThing	pivalyl-CoA mutase activity	Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA.	got7fsn_ti												EC:5.4.99.-|UM-BBD_reactionID:r1033		molecular_function											owl:Class	
GO:0060409	biolink:NamedThing	positive regulation of acetylcholine metabolic process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0018758	biolink:NamedThing	2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity	Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid.	got7fsn_ti												UM-BBD_reactionID:r0122		molecular_function											owl:Class	
GO:0050242	biolink:NamedThing	pyruvate, phosphate dikinase activity	Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate.	got7fsn_ti	pyruvic-phosphate dikinase activity|orthophosphate dikinase pyruvate|pyruvate,phosphate dikinase activity|pyruvate, Pi dikinase activity|pyruvate-inorganic phosphate dikinase activity|pyruvate-phosphate ligase activity|ATP:pyruvate, phosphate phosphotransferase activity|pyruvic-phosphate ligase activity|pyruvate-phosphate dikinase activity|pyruvate,orthophosphate dikinase activity|pyruvate-phosphate dikinase (phosphorylating)|PPDK											EC:2.7.9.1|MetaCyc:PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN|RHEA:10756|KEGG_REACTION:R00206		molecular_function											owl:Class	
GO:0030688	biolink:NamedThing	preribosome, small subunit precursor	A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.	got7fsn_ti	43S preribosome				Note that this complex is 43S in Saccharomyces.									cellular_component											owl:Class	
GO:0043320	biolink:NamedThing	natural killer cell degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.	got7fsn_ti	NK cell degranulation|natural killer cell granule exocytosis|NK cell granule exocytosis													biological_process											owl:Class	
GO:0010761	biolink:NamedThing	fibroblast migration	Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti	fibroblast cell migration													biological_process											owl:Class	
GO:0010294	biolink:NamedThing	abscisic acid glucosyltransferase activity	Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP.	got7fsn_ti												MetaCyc:RXN-8155|RHEA:31031		molecular_function											owl:Class	
GO:0071452	biolink:NamedThing	cellular response to singlet oxygen	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.	got7fsn_ti							mah	2009-12-16T04:39:46Z						biological_process											owl:Class	
GO:0000304	biolink:NamedThing	response to singlet oxygen	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.	got7fsn_ti														biological_process											owl:Class	
GO:0102042	biolink:NamedThing	dehydroquinate synthase activity	Catalysis of the reaction: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid + H2O + NAD = 3-dehydroquinate + ammonium + NADH + H+.	got7fsn_ti												RHEA:25956|MetaCyc:RXN-10032|EC:1.4.1.24		molecular_function											owl:Class	
GO:0043992	biolink:NamedThing	histone acetyltransferase activity (H3-K9 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K9 specific)													molecular_function											owl:Class	
GO:0051753	biolink:NamedThing	mannan synthase activity	Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.	got7fsn_ti	galactomannan beta-1,4-mannosyltransferase activity|mannan beta-1,4-mannosyltransferase activity													molecular_function											owl:Class	
GO:0010962	biolink:NamedThing	regulation of glucan biosynthetic process	Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.	got7fsn_ti							tb	2009-05-11T12:17:53Z						biological_process											owl:Class	
GO:0072567	biolink:NamedThing	chemokine (C-X-C motif) ligand 2 production	The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	MIP2 production|SCYB2 production|CXCL2 production|MIP-2 production						mah	2011-01-31T11:33:40Z						biological_process											owl:Class	
GO:0002868	biolink:NamedThing	negative regulation of B cell deletion	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.	got7fsn_ti	downregulation of B cell deletion|negative regulation of B lymphocyte deletion|negative regulation of B-cell deletion|down-regulation of B cell deletion|down regulation of B cell deletion|inhibition of B cell deletion|negative regulation of B-lymphocyte deletion													biological_process											owl:Class	
GO:1990753	biolink:NamedThing	equatorial cell cortex	The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression.	got7fsn_ti							kmv	2015-05-27T19:12:41Z						cellular_component											owl:Class	
GO:0097510	biolink:NamedThing	base-excision repair, AP site formation via deaminated base removal	A base-excision repair, AP site formation process occurring via excision of a deaminated base.	got7fsn_ti							pr	2013-10-08T14:44:01Z						biological_process											owl:Class	
GO:0050169	biolink:NamedThing	peptide-tryptophan 2,3-dioxygenase activity	Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine.	got7fsn_ti	tryptophan pyrrolooxygenase activity|peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)|peptidyltryptophan 2,3-dioxygenase activity|pyrrolooxygenase activity											MetaCyc:PEPTIDE-TRYPTOPHAN-23-DIOXYGENASE-RXN|EC:1.13.11.26		molecular_function											owl:Class	
GO:0007564	biolink:NamedThing	regulation of chitin-based cuticle tanning	Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning.	got7fsn_ti	regulation of cuticle tanning|regulation of cuticle hardening													biological_process											owl:Class	
GO:0102162	biolink:NamedThing	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase	Catalysis of the reaction: 8'-apo-beta,psi-caroten-8'-al + O2 <=> all-trans-retinal + 2,6-dimethylocta-2,4,6-trienedial.	got7fsn_ti												RHEA:26385|EC:1.13.11.75|MetaCyc:RXN-11783		molecular_function											owl:Class	
GO:0050956	biolink:NamedThing	electroception	The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.	got7fsn_ti	electroception sense|electroceptive sense											Wikipedia:Electroreception		biological_process											owl:Class	
GO:0045772	biolink:NamedThing	positive regulation of autophagosome size	Any process that increases autophagosome size.	got7fsn_ti	activation of autophagic vacuole size|up-regulation of autophagic vacuole size|stimulation of autophagic vacuole size|upregulation of autophagic vacuole size|up regulation of autophagic vacuole size|positive regulation of autophagic vacuole size													biological_process											owl:Class	
GO:0052768	biolink:NamedThing	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity	Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.	got7fsn_ti	alpha-1,3-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|1,3-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|1,3-alpha-mannosidase activity|alpha-1,3-mannosidase activity						ai	2011-09-30T12:55:24Z				EC:3.1.1.-		molecular_function											owl:Class	
GO:0044876	biolink:NamedThing	hercynylselenocysteine synthase	Catalysis of the reaction: 2 L-selenocysteine + 2 hercynine + O2 <=> 2 H2O + 2 hercynylselenocysteine.	got7fsn_ti							jl	2014-12-15T11:56:12Z				MetaCyc:RXN-15803|RHEA:42680		molecular_function											owl:Class	
GO:0102184	biolink:NamedThing	cycloartenol 4alpha-methyl oxidase activity	Catalysis of the reaction: cycloartenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-11946		molecular_function											owl:Class	
GO:0000760	biolink:NamedThing	adaptation to pheromone regulating conjugation with mutual genetic exchange	In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses.	got7fsn_ti	adaptation to pheromone involved conjugation without cellular fusion|desensitization to pheromone during conjugation without cellular fusion													biological_process											owl:Class	
GO:0032268	biolink:NamedThing	regulation of cellular protein metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.	got7fsn_ti	regulation of cellular protein metabolism													biological_process											owl:Class	
GO:0090171	biolink:NamedThing	chondrocyte morphogenesis	The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.	got7fsn_ti							tb	2009-12-11T10:36:02Z						biological_process											owl:Class	
GO:0047987	biolink:NamedThing	hydroperoxide dehydratase activity	Catalysis of the reaction: (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate = (9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate + H2O.	got7fsn_ti	(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]|linoleic acid hydroperoxide isomerase|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase activity|hydroperoxide isomerase activity|linoleate hydroperoxide isomerase|HPI											MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN|RHEA:25075|EC:4.2.1.92		molecular_function											owl:Class	
GO:0008124	biolink:NamedThing	4-alpha-hydroxytetrahydrobiopterin dehydratase activity	Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O.	got7fsn_ti	4a-hydroxytetrahydrobiopterin dehydratase activity|tetrahydrobiopterin dehydratase activity|pterin-4alpha-carbinolamine dehydratase activity|4a-hydroxytetrahydrobiopterin hydro-lyase activity|pterin-4-alpha-carbinolamine dehydratase activity|(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]|4alpha-hydroxy-tetrahydropterin dehydratase activity|pterin-4a-carbinolamine dehydratase activity|4-alpha-hydroxy-tetrahydropterin dehydratase activity											Reactome:R-HSA-71146|KEGG_REACTION:R04734|EC:4.2.1.96|RHEA:11920|MetaCyc:RXN-7908		molecular_function											owl:Class	
GO:0030701	biolink:NamedThing	NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity	Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].	got7fsn_ti	NAD--azoferredoxin (ADP-ribose)transferase activity|NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity|NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase activity|ADP-ribosyltransferase activity|NAD-azoferredoxin (ADPribose)transferase activity											EC:2.4.2.37|MetaCyc:2.4.2.37-RXN|RHEA:18077		molecular_function											owl:Class	
GO:0008292	biolink:NamedThing	acetylcholine biosynthetic process	The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline.	got7fsn_ti	acetylcholine formation|acetylcholine anabolism|acetylcholine synthesis|acetylcholine biosynthesis													biological_process											owl:Class	
GO:0047531	biolink:NamedThing	2,5-diaminovalerate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + ornithine = 5-amino-2-oxopentanoate + L-glutamate.	got7fsn_ti	diamino-acid aminotransferase activity|diamino acid aminotransferase activity|diamino-acid transaminase activity|2,5-diaminopentanoate:2-oxoglutarate aminotransferase activity|2,5-diaminovalerate aminotransferase activity											RHEA:16017|EC:2.6.1.8|MetaCyc:25-DIAMINOVALERATE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R03248		molecular_function											owl:Class	
GO:0009045	biolink:NamedThing	xylose isomerase activity	Catalysis of the reaction: D-xylose = D-xylulose.	got7fsn_ti	D-xylose ketol-isomerase activity|D-xylose isomerase activity|D-xylose aldose-ketose-isomerase activity|D-xylose ketoisomerase activity											EC:5.3.1.5|RHEA:22816|MetaCyc:XYLISOM-RXN		molecular_function											owl:Class	
GO:0031835	biolink:NamedThing	substance P receptor binding	Binding to a substance P receptor.	got7fsn_ti	neurokinin-1 receptor binding|substance P receptor ligand													molecular_function											owl:Class	
GO:0072653	biolink:NamedThing	interferon-omega production	The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IFNW production|IFN-omega production|interferon-omega secretion				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072654			biological_process											owl:Class	
GO:0047368	biolink:NamedThing	UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H(+) + UDP-N-acetyl-D-galactosamine 4,6-disulfate.	got7fsn_ti	uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase activity|3'-phosphoadenylyl-sulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase activity|UDP-N-acetylgalactosamine-4-sulphate sulphotransferase activity|uridine diphosphoacetylgalactosamine 4-sulfate sulfotransferase activity											KEGG_REACTION:R04476|EC:2.8.2.7|RHEA:14337|MetaCyc:2.8.2.7-RXN		molecular_function											owl:Class	
GO:0043918	biolink:NamedThing	cadaverine aminopropyltransferase activity	Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine.	got7fsn_ti	cadaverine aminopropyl transferase activity											EC:2.5.1.104		molecular_function											owl:Class	
GO:0050183	biolink:NamedThing	phosphatidylcholine 12-monooxygenase activity	Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O(2) = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H(2)O + NAD(+).	got7fsn_ti	oleate Delta(12)-hydroxylase activity|oleate delta12-monooxygenase activity|oleate D12-hydroxylase activity|ricinoleic acid synthase activity|oleate delta12-hydroxylase activity|1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen oxidoreductase (12-hydroxylating)											EC:1.14.18.4|MetaCyc:PHOSPHATIDYLCHOLINE-12-MONOOXYGENASE-RXN|RHEA:46360|KEGG_REACTION:R03476		molecular_function											owl:Class	
GO:0043286	biolink:NamedThing	regulation of poly(3-hydroxyalkanoate) biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.	got7fsn_ti	regulation of poly(3-hydroxyalkanoate) synthesis|regulation of poly(3-hydroxyalkanoate) anabolism|regulation of PHA|regulation of poly(3-hydroxyalkanoate) formation|regulation of poly(3-hydroxyalkanoate) biosynthesis													biological_process											owl:Class	
GO:0005452	biolink:NamedThing	inorganic anion exchanger activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).	got7fsn_ti												Reactome:R-HSA-427666|Reactome:R-HSA-5656248|Reactome:R-HSA-425577|Reactome:R-HSA-1237038|Reactome:R-HSA-1247665|Reactome:R-HSA-5627737|Reactome:R-HSA-425482		molecular_function											owl:Class	
GO:0035810	biolink:NamedThing	positive regulation of urine volume	Any process that increases the amount of urine excreted from the body over a unit of time.	got7fsn_ti	diuresis|elevation of urinary volume|increase in urine flow						bf	2011-04-20T01:19:38Z						biological_process											owl:Class	
GO:0008808	biolink:NamedThing	cardiolipin synthase activity	Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.	got7fsn_ti	cardiolipin synthetase activity|diphosphatidylglycerol synthase activity|cardiolipin synthetase 2 activity|cardiolipin synthase 2 activity										GO:0043788	RHEA:31451|MetaCyc:CARDIOLIPSYN-RXN		molecular_function											owl:Class	
GO:0033406	biolink:NamedThing	UCC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UCC codon.	got7fsn_ti	TCC codon-amino acid adaptor activity|serine tRNA				Note that in the standard genetic code, TCC codes for serine.									molecular_function											owl:Class	
GO:0050860	biolink:NamedThing	negative regulation of T cell receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.	got7fsn_ti	down regulation of T cell receptor signaling pathway|negative regulation of T lymphocyte receptor signalling pathway|inhibition of T cell receptor signaling pathway|negative regulation of T-cell receptor signaling pathway|negative regulation of T-lymphocyte receptor signaling pathway|negative regulation of T-lymphocyte receptor signalling pathway|down-regulation of T cell receptor signaling pathway|negative regulation of TCR signaling pathway|negative regulation of T lymphocyte receptor signaling pathway|downregulation of T cell receptor signaling pathway|negative regulation of T cell receptor signalling pathway													biological_process											owl:Class	
GO:1900247	biolink:NamedThing	regulation of cytoplasmic translational elongation	Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.	got7fsn_ti							vw	2012-04-03T05:07:02Z						biological_process											owl:Class	
GO:0039547	biolink:NamedThing	suppression by virus of host TRAF activity	Any process in which a virus stops, prevents, or reduces the activity of a host TRAF (tumor necrosis factor receptor-associated factor) protein. TRAFs are intracellular signal transducers that lie downstream of receptors including RIG-I, MDA-5 and Toll-like receptors (TLR) and transfer the signal to other intracellular signaling components.	got7fsn_ti	inhibition of host TRAFs by virus				This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-01-19T03:12:15Z						biological_process											owl:Class	
GO:0052886	biolink:NamedThing	9,9'-dicis-carotene:quinone oxidoreductase activity	Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol.	got7fsn_ti	ZDS activity|zeta-carotene desaturase activity|9,9'-di-cis-zeta-carotene desaturase activity											EC:1.3.5.6|RHEA:30959|MetaCyc:RXN-11356|KEGG_REACTION:R09656		molecular_function											owl:Class	
GO:0042735	biolink:NamedThing	protein body	A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0004366	biolink:NamedThing	glycerol-3-phosphate O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.	got7fsn_ti	alpha-glycerophosphate acyltransferase activity|glycerol phosphate transacylase activity|sn-glycerol 3-phosphate acyltransferase activity|glycerophosphate transacylase activity|ACP:sn-glycerol-3-phosphate acyltransferase activity|glycerol phosphate acyltransferase activity|glycerol 3-phosphate acyltransferase activity|sn-glycerol-3-phosphate acyltransferase activity|glycerophosphate acyltransferase activity|acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase activity|3-glycerophosphate acyltransferase activity											EC:2.3.1.15|Reactome:R-HSA-75886|Reactome:R-HSA-1482695|RHEA:15325|MetaCyc:RXN-1381|Reactome:R-HSA-549112		molecular_function											owl:Class	
GO:0090680	biolink:NamedThing	disruption by virus of host outer membrane	A process by which a virus has a negative effect on the functioning of a host outer membrane.	got7fsn_ti							tb	2016-05-04T15:52:02Z						biological_process											owl:Class	
GO:0061824	biolink:NamedThing	cytosolic ciliogenesis	The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm.	got7fsn_ti	intracellular ciliogenesis						dph	2017-01-14T14:24:17Z						biological_process											owl:Class	
GO:0061609	biolink:NamedThing	fructose-1-phosphate aldolase activity	Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde.	got7fsn_ti							dph	2014-03-28T08:54:24Z				Reactome:R-HSA-5656438|RHEA:30851|Reactome:R-HSA-70342		molecular_function											owl:Class	
GO:0004139	biolink:NamedThing	deoxyribose-phosphate aldolase activity	Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.	got7fsn_ti	deoxyribose-5-phosphate aldolase activity|2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase activity|phosphodeoxyriboaldolase activity|2-deoxyribose-5-phosphate aldolase activity|deoxyriboaldolase activity|2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)											KEGG_REACTION:R01066|Reactome:R-HSA-6787321|MetaCyc:DEOXYRIBOSE-P-ALD-RXN|EC:4.1.2.4|RHEA:12821		molecular_function											owl:Class	
GO:0036121	biolink:NamedThing	double-stranded DNA helicase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix.	got7fsn_ti	double-stranded DNA-dependent ATPase activity|dsDNA-dependent ATP-dependent DNA helicase activity|dsDNA-dependent ATPase activity|double-stranded DNA-dependent ATP-dependent DNA helicase activity						bf	2012-02-20T02:53:51Z			GO:0033676			molecular_function											owl:Class	
GO:0051448	biolink:NamedThing	gonadotropin-releasing hormone binding	Binding to gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.	got7fsn_ti	GnRH binding|gonadotrophin releasing hormone binding													molecular_function											owl:Class	
GO:0042807	biolink:NamedThing	central vacuole	A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination.	got7fsn_ti														cellular_component											owl:Class	
GO:0086030	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation	An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation.	got7fsn_ti	adrenergic receptor signaling pathway involved in cardiac muscle relaxation via activation of AC|Gs-coupled adrenergic receptor signaling pathway involved in cardiac muscle relaxation|adrenergic receptor signaling pathway involved in cardiac muscle relaxation|adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation|adrenergic receptor-induced cardiac relaxation						tb	2011-11-11T02:53:24Z						biological_process											owl:Class	
GO:0086023	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	A series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart.	got7fsn_ti	adrenergic receptor signalling pathway involved in heart process|adrenergic receptor signaling pathway involved in heart process|beta-adrenergic receptor signalling pathway involved in heart process						tb	2011-11-11T02:51:03Z						biological_process											owl:Class	
GO:0034452	biolink:NamedThing	dynactin binding	Binding to a dynactin complex; a large protein complex that activates dynein-based motor activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0031764	biolink:NamedThing	type 1 galanin receptor binding	Binding to a type 1 galanin receptor.	got7fsn_ti	type 1 galanin receptor ligand													molecular_function											owl:Class	
GO:0043801	biolink:NamedThing	hexulose-6-phosphate synthase activity	Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate.	got7fsn_ti												EC:4.1.2.43|MetaCyc:R10-RXN|RHEA:25201		molecular_function											owl:Class	
GO:0002539	biolink:NamedThing	prostaglandin production involved in inflammatory response	The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	prostaglandin production involved in acute inflammatory response													biological_process											owl:Class	
GO:0039548	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.	got7fsn_ti	inhibition of host IRF3 by virus|suppression by virus of host interferon regulatory factor 3|inhibition of IRF3-dependent antiviral response|suppression by virus of host IRF3 activity	https://github.com/geneontology/go-ontology/issues/21985			This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-01-19T04:04:26Z						biological_process											owl:Class	
GO:0008826	biolink:NamedThing	cysteine sulfinate desulfinase activity	Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite.	got7fsn_ti	cysteine sulphinate desulphinase activity											RHEA:28278|MetaCyc:RXN0-279		molecular_function											owl:Class	
GO:0102390	biolink:NamedThing	mycophenolic acid acyl-glucuronide esterase activity	Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate.	got7fsn_ti												MetaCyc:RXN-13605|RHEA:34179|EC:3.1.1.93		molecular_function											owl:Class	
GO:0048556	biolink:NamedThing	microsporocyte nucleus	The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte.	got7fsn_ti	microspore mother cell nucleus|pollen mother cell nucleus										GO:0043074			cellular_component											owl:Class	
GO:0007119	biolink:NamedThing	budding cell isotropic bud growth	Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.	got7fsn_ti	isotropic bud growth													biological_process											owl:Class	
GO:0047666	biolink:NamedThing	ammonia kinase activity	Catalysis of the reaction: ATP + NH(4)(+) = ADP + 3 H(+) + phosphoramidate.	got7fsn_ti	phosphoramidate-adenosine diphosphate phosphotransferase activity|ATP:ammonia phosphotransferase activity|phosphoramidate-ADP-phosphotransferase activity											MetaCyc:AMMONIA-KINASE-RXN|RHEA:11024|EC:2.7.3.8|KEGG_REACTION:R00141		molecular_function											owl:Class	
GO:0019918	biolink:NamedThing	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine.	got7fsn_ti												RESID:AA0069|RESID:AA0067		biological_process											owl:Class	
GO:0048822	biolink:NamedThing	enucleate erythrocyte development	The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti	enucleate red blood cell development|enucleate RBC development													biological_process											owl:Class	
GO:0000149	biolink:NamedThing	SNARE binding	Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.	got7fsn_ti	SNAP receptor binding											Reactome:R-HSA-888589|Reactome:R-HSA-210430|Reactome:R-HSA-9023173|Reactome:R-HSA-372529|Reactome:R-HSA-374899|Reactome:R-HSA-380901|Reactome:R-HSA-372505|Reactome:R-HSA-376369|Reactome:R-HSA-380905|Reactome:R-HSA-380869|Reactome:R-HSA-265166|Reactome:R-HSA-376364|Reactome:R-HSA-374922|Reactome:R-HSA-376357|Reactome:R-HSA-380574|Reactome:R-HSA-210426|Reactome:R-HSA-917744		molecular_function											owl:Class	
GO:0015514	biolink:NamedThing	nitrite efflux transmembrane transporter activity	Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	nitrite extrusion permease activity													molecular_function											owl:Class	
GO:0071737	biolink:NamedThing	IgG B cell receptor complex	An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	got7fsn_ti	surface IgG2|surface IgG4|membrane-bound IgG2c|surface IgG2c|membrane-bound IgG2b|membrane-bound IgG2a|membrane-bound IgG2|surface IgG1|membrane-bound IgG4|surface IgG|surface IgG2b|membrane-bound IgG3|membrane-bound IgG|surface IgG2a|membrane-bound IgG1|surface IgG3				Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0032046	biolink:NamedThing	micropexophagy-specific membrane apparatus	A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole.	got7fsn_ti	MIPA|micropexophagic apparatus													cellular_component											owl:Class	
GO:0047421	biolink:NamedThing	N-acyl-D-glutamate deacylase activity	Catalysis of the reaction: N-acyl-D-glutamate + H(2)O = D-glutamate + a carboxylate.	got7fsn_ti	N-acyl-D-glutamate amidohydrolase activity											KEGG_REACTION:R01581|RHEA:12833|EC:3.5.1.82|MetaCyc:3.5.1.82-RXN		molecular_function											owl:Class	
GO:0106142	biolink:NamedThing	rRNA (adenine-N1-)-methyltransferase activity	Catalysis of the reaction:  S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA.	got7fsn_ti	25S rRNA (adenine(645)-N(1))-methyltransferase|25S rRNA m(1)A(645) methyltransferase				The m(1)A modification at position 645 in the large rRNA is highly conserved in eukaryotes.		hjd	2018-08-22T20:13:21Z				EC:2.1.1.287|RHEA:43792		molecular_function											owl:Class	
GO:0031866	biolink:NamedThing	EP3 subtype prostaglandin E2 receptor binding	Binding to an EP3 subtype prostaglandin E2 receptor.	got7fsn_ti	prostanoid EP3 receptor binding|EP3 subtype prostaglandin E2 receptor ligand													molecular_function											owl:Class	
GO:0060828	biolink:NamedThing	regulation of canonical Wnt signaling pathway	Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	got7fsn_ti	catenin import into nucleus|regulation of catenin import into nucleus|regulation of catenin protein nuclear translocation|regulation of Wnt receptor signaling pathway through beta-catenin|regulation of canonical Wnt receptor signalling pathway|regulation of canonical Wnt-activated signaling pathway|regulation of canonical Wnt receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/15268|https://github.com/geneontology/go-ontology/issues/13686					dph	2009-08-11T01:54:47Z			GO:0035412|GO:0035411			biological_process											owl:Class	
GO:0103066	biolink:NamedThing	4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity	Catalysis of the reaction: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 4alpha-methyl-5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H.	got7fsn_ti												EC:1.1.1.170|MetaCyc:RXN66-18		molecular_function											owl:Class	
GO:0038108	biolink:NamedThing	negative regulation of appetite by leptin-mediated signaling pathway	A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food.	got7fsn_ti	inhibition of appetite by leptin signaling|negative regulation of appetite by leptin-mediated signalling pathway|suppression of appetite by leptin-mediated signaling pathway|reduction of appetite by leptin-mediated signaling						bf	2012-03-09T11:14:36Z						biological_process											owl:Class	
GO:0032099	biolink:NamedThing	negative regulation of appetite	Any process that reduces appetite.	got7fsn_ti	negative regulation of hunger|down regulation of appetite|appetite suppression|downregulation of appetite|down-regulation of appetite|inhibition of appetite													biological_process											owl:Class	
GO:0034420	biolink:NamedThing	co-translational protein acetylation	The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome.	got7fsn_ti	co-translational protein amino acid acetylation|cotranslational protein amino acid acetylation													biological_process											owl:Class	
GO:0034540	biolink:NamedThing	3-monobromobisphenol A reductive dehalogenase activity	Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr.	got7fsn_ti												UM-BBD_reactionID:r0824|EC:1.97.1.-		molecular_function											owl:Class	
GO:0021608	biolink:NamedThing	accessory nerve formation	The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	got7fsn_ti	CN XI biosynthesis|CN XI formation													biological_process											owl:Class	
GO:0030103	biolink:NamedThing	vasopressin secretion	The regulated release of vasopressin from secretory granules into the blood.	got7fsn_ti														biological_process											owl:Class	
GO:0060396	biolink:NamedThing	growth hormone receptor signaling pathway	The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.	got7fsn_ti	GH receptor signaling pathway|cellular response to growth hormone|growth hormone receptor signalling pathway													biological_process											owl:Class	
GO:0047464	biolink:NamedThing	heparosan-N-sulfate-glucuronate 5-epimerase activity	Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate.	got7fsn_ti	heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity|D-glucuronyl C-5 epimerase activity|heparosan-N-sulphate-glucuronate 5-epimerase activity|polyglucuronate epimerase activity|heparosan epimerase activity|poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity|C-5 uronosyl epimerase activity											EC:5.1.3.17|RHEA:20197|MetaCyc:5.1.3.17-RXN		molecular_function											owl:Class	
GO:0001325	biolink:NamedThing	formation of extrachromosomal circular DNA	Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.	got7fsn_ti	assembly of extrachromosomal circular DNA													biological_process											owl:Class	
GO:0017124	biolink:NamedThing	SH3 domain binding	Binding to a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.	got7fsn_ti														molecular_function											owl:Class	
GO:0018689	biolink:NamedThing	naphthalene disulfonate 1,2-dioxygenase activity	Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene).	got7fsn_ti	naphthalene disulphonate 1,2-dioxygenase activity											UM-BBD_enzymeID:e0249		molecular_function											owl:Class	
GO:0050540	biolink:NamedThing	2-aminomuconate deaminase activity	Catalysis of the reaction: 2-aminomuconate + H(2)O + H(+) = (Z)-5-oxohex-2-enedioate + NH(4)(+).	got7fsn_ti	2-aminomuconate aminohydrolase activity											MetaCyc:3.5.99.5-RXN|RHEA:20996|KEGG_REACTION:R03887|EC:3.5.99.5		molecular_function											owl:Class	
GO:0102921	biolink:NamedThing	mannosylglycerate synthase activity	Catalysis of the reaction: GDP-alpha-D-mannose + D-glycerate <=> H+ + 2-(alpha-D-mannosyl)-D-glycerate + GDP.	got7fsn_ti												EC:2.4.1.269|MetaCyc:RXN-8849|RHEA:30639		molecular_function											owl:Class	
GO:0047755	biolink:NamedThing	isocitrate epimerase activity	Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate.	got7fsn_ti	(1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase activity											EC:5.1.2.6|KEGG_REACTION:R02318|MetaCyc:ISOCITRATE-EPIMERASE-RXN|RHEA:10820		molecular_function											owl:Class	
GO:0070451	biolink:NamedThing	cell hair	A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.	got7fsn_ti	imaginal disc-derived wing hair|non-sensory hair											Wikipedia:Membrane_nanotube		cellular_component											owl:Class	
GO:0080107	biolink:NamedThing	8-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate.	got7fsn_ti							dhl	2009-04-23T04:30:08Z						molecular_function											owl:Class	
GO:0033807	biolink:NamedThing	icosanoyl-CoA synthase activity	Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+.	got7fsn_ti	C18-CoA elongase activity|stearoyl-CoA elongase activity|acyl-CoA elongase activity|stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) activity											MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN|EC:2.3.1.119		molecular_function											owl:Class	
GO:1990021	biolink:NamedThing	Schaffer axon collateral	Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1.	got7fsn_ti	Schaffer collateral						pr	2013-01-10T16:06:17Z				NIF_Subcellular:nlx_subcell_20090511		cellular_component											owl:Class	
GO:0035170	biolink:NamedThing	lymph gland crystal cell differentiation	The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.	got7fsn_ti														biological_process											owl:Class	
GO:0031740	biolink:NamedThing	type A cholecystokinin receptor binding	Binding to a type A cholecystokinin receptor.	got7fsn_ti	type A cholecystokinin receptor ligand													molecular_function											owl:Class	
GO:0031739	biolink:NamedThing	cholecystokinin receptor binding	Binding to a cholecystokinin receptor.	got7fsn_ti	cholecystokinin receptor ligand													molecular_function											owl:Class	
GO:0030418	biolink:NamedThing	nicotianamine biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.	got7fsn_ti	nicotianamine formation|nicotianamine anabolism|nicotianamine synthesis|nicotianamine biosynthesis													biological_process											owl:Class	
GO:0035297	biolink:NamedThing	regulation of Malpighian tubule diameter	Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells.	got7fsn_ti														biological_process											owl:Class	
GO:0051990	biolink:NamedThing	(R)-2-hydroxyglutarate dehydrogenase activity	Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.	got7fsn_ti	D-2-hydroxyglutarate dehydrogenase activity											EC:1.1.99.39|RHEA:38295|Reactome:R-HSA-880053|Reactome:R-HSA-880007		molecular_function											owl:Class	
GO:0000827	biolink:NamedThing	inositol-1,3,4,5,6-pentakisphosphate kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.	got7fsn_ti												Reactome:R-HSA-1855223|EC:2.7.4.21|Reactome:R-HSA-1855181		molecular_function											owl:Class	
GO:0008204	biolink:NamedThing	ergosterol metabolic process	The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light.	got7fsn_ti	ergosterol metabolism													biological_process											owl:Class	
GO:0047680	biolink:NamedThing	aryl-acylamidase activity	Catalysis of the reaction: anilide + H(2)O = a carboxylate + aniline + H(+).	got7fsn_ti	AAA-2|aryl-acylamide amidohydrolase activity|pseudocholinesterase (associated with arylacylamidase)|brain acetylcholinesterase (is associated with AAA-2)|AAA-1											KEGG_REACTION:R01862|RHEA:20297|EC:3.5.1.13|MetaCyc:ARYL-ACYLAMIDASE-RXN		molecular_function											owl:Class	
GO:0042286	biolink:NamedThing	glutamate-1-semialdehyde 2,1-aminomutase activity	Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.	got7fsn_ti	glutamate-1-semialdehyde aminotransferase activity|(S)-4-amino-5-oxopentanoate 4,5-aminomutase activity											KEGG_REACTION:R02272|RHEA:14265|EC:5.4.3.8|MetaCyc:GSAAMINOTRANS-RXN		molecular_function											owl:Class	
GO:0035975	biolink:NamedThing	carbamoyl phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.	got7fsn_ti	carbamoyl phosphate degradation|carbamoyl phosphate catabolism|carbamoyl phosphate breakdown						bf	2011-08-16T11:41:13Z						biological_process											owl:Class	
GO:0052786	biolink:NamedThing	alpha-linked polysaccharide catabolism to maltotriose	The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose.	got7fsn_ti	alpha-amylase-mediated polysaccharide catabolism, producing maltotriose|maltotriose-forming alpha-amylase activity						ai	2011-10-04T09:59:59Z						biological_process											owl:Class	
GO:0036148	biolink:NamedThing	phosphatidylglycerol acyl-chain remodeling	Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.	got7fsn_ti							bf	2012-03-14T01:14:23Z						biological_process											owl:Class	
GO:0046471	biolink:NamedThing	phosphatidylglycerol metabolic process	The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.	got7fsn_ti	phosphatidylglycerol metabolism													biological_process											owl:Class	
GO:0102748	biolink:NamedThing	geranylgeranyl-chlorophyll a reductase activity	Catalysis of the reaction: H+ + geranylgeranyl-chlorophyll a + NADPH = dihydrogeranylgeranyl-chlorophyll a + NADP.	got7fsn_ti												MetaCyc:RXN-7664		molecular_function											owl:Class	
GO:0060645	biolink:NamedThing	peripheral mammary gland bud epithelial cell differentiation	The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically.	got7fsn_ti							dph	2009-05-29T08:06:16Z						biological_process											owl:Class	
GO:0034562	biolink:NamedThing	2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity	Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O.	got7fsn_ti												UM-BBD_reactionID:r0864		molecular_function											owl:Class	
GO:0031760	biolink:NamedThing	Edg-7 lysophosphatidic acid receptor binding	Binding to an Edg-7 lysophosphatidic acid receptor.	got7fsn_ti	Edg-7 lysophosphatidic acid receptor ligand|LPA3 receptor binding													molecular_function											owl:Class	
GO:0009650	biolink:NamedThing	UV protection	Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.	got7fsn_ti	ultraviolet protection|ultraviolet resistance|ultraviolet tolerance|UV resistance|UV tolerance													biological_process											owl:Class	
GO:0102728	biolink:NamedThing	campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity	Catalysis of the reaction: (5alpha)-campestan-3-one + NADP = H+ + campest-4-en-3-one + NADPH.	got7fsn_ti												RHEA:54416|MetaCyc:RXN-711		molecular_function											owl:Class	
GO:0097573	biolink:NamedThing	glutathione oxidoreductase activity	Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione.	got7fsn_ti					Note that this activity is different from GO:0015038 'glutathione disulfide oxidoreductase activity'. See PMID:18992757: "Grxs [glutaredoxins] can also reduce mixed disulfides between proteins or low molecular weight thiols and GSH in reactions that require only their N-terminal active- site cysteine. It is important to note that the reduction of glutathionylated substrates through the monothiol mechanism seems to be the major activity of Grxs; all dithiol Grxs described so far catalyze these reactions, but not all dithiol Grxs catalyze the reduction of protein disulfides by the dithiol mechanism".		pr	2014-02-19T13:41:38Z						molecular_function											owl:Class	
GO:0043908	biolink:NamedThing	Ser(Gly)-tRNA(Ala) hydrolase activity	Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala).	got7fsn_ti	Ser(Gly)-tRNAAla hydrolase activity											EC:3.1.1.-		molecular_function											owl:Class	
GO:0009419	biolink:NamedThing	pilus tip	The pointed extremity furthest from the cell of a pilus.	got7fsn_ti	fimbrial tip													cellular_component											owl:Class	
GO:0043785	biolink:NamedThing	cinnamoyl-CoA:phenyllactate CoA-transferase activity	Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate.	got7fsn_ti	(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase activity|FldA											MetaCyc:2.8.3.17-RXN|KEGG_REACTION:R07796|EC:2.8.3.17|RHEA:15601		molecular_function											owl:Class	
GO:0071313	biolink:NamedThing	cellular response to caffeine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.	got7fsn_ti							mah	2009-12-10T04:52:51Z						biological_process											owl:Class	
GO:0005415	biolink:NamedThing	nucleoside:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in).	got7fsn_ti	sodium-dependent nucleoside transporter activity|nucleoside-sodium cotransporter activity										GO:0008522	Reactome:R-HSA-109538|Reactome:R-HSA-109530|Reactome:R-HSA-109539		molecular_function											owl:Class	
GO:0008196	biolink:NamedThing	vitellogenin receptor activity	Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis.	got7fsn_ti														molecular_function											owl:Class	
GO:0051120	biolink:NamedThing	hepoxilin A3 synthase activity	Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.	got7fsn_ti												Reactome:R-HSA-8942208|Reactome:R-HSA-2161794		molecular_function											owl:Class	
GO:0043128	biolink:NamedThing	positive regulation of 1-phosphatidylinositol 4-kinase activity	Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase.	got7fsn_ti	activation of 1-phosphatidylinositol 4-kinase activity|positive regulation of PI4K activity|up regulation of 1-phosphatidylinositol 4-kinase activity|up-regulation of 1-phosphatidylinositol 4-kinase activity|stimulation of 1-phosphatidylinositol 4-kinase activity|upregulation of 1-phosphatidylinositol 4-kinase activity													biological_process											owl:Class	
GO:0034898	biolink:NamedThing	hexadecyltrimethylammonium chloride monooxygenase activity	Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O.	got7fsn_ti												EC:1.13.12.-|UM-BBD_reactionID:r1373		molecular_function											owl:Class	
GO:0008755	biolink:NamedThing	O antigen polymerase activity	Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide.	got7fsn_ti	O-antigen polymerase activity													molecular_function											owl:Class	
GO:0033513	biolink:NamedThing	L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide.	got7fsn_ti	L-lysine degradation to acetyl-CoA via 5-aminopentanamide|L-lysine breakdown to acetyl-CoA via 5-aminopentanamide											MetaCyc:PWY-5280		biological_process											owl:Class	
GO:0042248	biolink:NamedThing	maintenance of polarity of follicular epithelium	The maintenance of an established polarized follicular epithelial sheet.	got7fsn_ti														biological_process											owl:Class	
GO:0030908	biolink:NamedThing	protein splicing	The post-translational removal of peptide sequences from within a protein sequence.	got7fsn_ti												Wikipedia:Protein_splicing		biological_process											owl:Class	
GO:0022840	biolink:NamedThing	leak channel activity	Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.	got7fsn_ti														molecular_function											owl:Class	
GO:0102313	biolink:NamedThing	1,8-cineole synthase activity	Catalysis of the reaction: geranyl diphosphate(3-) + H2O <=> 1,8-cineole + diphosphoric acid.	got7fsn_ti												RHEA:32543|EC:4.2.3.108|MetaCyc:RXN-12980		molecular_function											owl:Class	
GO:0018683	biolink:NamedThing	camphor 5-monooxygenase activity	Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O.	got7fsn_ti	methylene hydroxylase activity|D-camphor-exo-hydroxylase activity|camphor hydroxylase activity|methylene monooxygenase activity|d-camphor monooxygenase activity|camphor 5-exo-hydroxylase activity|bornanone 5-exo-hydroxylase activity|2-bornanone 5-exo-hydroxylase activity|camphor methylene hydroxylase activity|camphor 5-exohydroxylase activity|(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)|cytochrome p450-cam activity|camphor 5-exo-methylene hydroxylase activity											MetaCyc:R541-RXN|UM-BBD_enzymeID:e0300|EC:1.14.15.1|RHEA:13525		molecular_function											owl:Class	
GO:0140498	biolink:NamedThing	mannan polymerase I complex	A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the priming and elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p and Van1p.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19817					pg	2020-07-22T14:34:23Z						cellular_component											owl:Class	
GO:0050302	biolink:NamedThing	indole-3-acetaldehyde oxidase activity	Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+).	got7fsn_ti	(indol-3-yl)acetaldehyde:oxygen oxidoreductase activity|IAAld oxidase activity|indoleacetaldehyde oxidase activity|indole-3-acetaldehyde:oxygen oxidoreductase activity|IAA oxidase activity|AO1											RHEA:16277|EC:1.2.3.7|MetaCyc:INDOLE-3-ACETALDEHYDE-OXIDASE-RXN|KEGG_REACTION:R02681		molecular_function											owl:Class	
GO:0018391	biolink:NamedThing	C-terminal peptidyl-glutamic acid tyrosinylation	The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0047716	biolink:NamedThing	imidazole N-acetyltransferase activity	Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA.	got7fsn_ti	imidazole acetylase activity|imidazole acetyltransferase activity|acetyl-CoA:imidazole N-acetyltransferase activity											KEGG_REACTION:R03621|MetaCyc:IMIDAZOLE-N-ACETYLTRANSFERASE-RXN|RHEA:15813|EC:2.3.1.2		molecular_function											owl:Class	
GO:1900582	biolink:NamedThing	o-orsellinic acid metabolic process	The chemical reactions and pathways involving o-orsellinic acid.	got7fsn_ti	o-orsellinic acid metabolism						di	2012-05-15T06:47:42Z						biological_process											owl:Class	
GO:0036432	biolink:NamedThing	all-trans undecaprenol kinase activity	Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.	got7fsn_ti							bf	2013-09-16T14:21:04Z				RHEA:23752		molecular_function											owl:Class	
GO:1900580	biolink:NamedThing	(17Z)-protosta-17(20),24-dien-3beta-ol catabolic process	The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.	got7fsn_ti	(17Z)-protosta-17(20),24-dien-3beta-ol catabolism|(17Z)-protosta-17(20),24-dien-3beta-ol degradation|(17Z)-protosta-17(20),24-dien-3beta-ol breakdown						di	2012-05-15T06:47:30Z						biological_process											owl:Class	
GO:0004321	biolink:NamedThing	fatty-acyl-CoA synthase activity	Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.	got7fsn_ti	yeast fatty acid synthase activity|acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl- reducing)|fatty acyl CoA synthase activity											EC:2.3.1.86|RHEA:22896|MetaCyc:FATTY-ACYL-COA-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0033435	biolink:NamedThing	AUA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AUA codon.	got7fsn_ti	ATA codon-amino acid adaptor activity|isoleucine tRNA				Note that in the standard genetic code, ATA codes for isoleucine.									molecular_function											owl:Class	
GO:0009746	biolink:NamedThing	response to hexose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.	got7fsn_ti	response to hexose stimulus													biological_process											owl:Class	
GO:0006391	biolink:NamedThing	transcription initiation from mitochondrial promoter	A transcription initiation process that takes place at a promoter on the mitochondrial chromosome, and results in RNA synthesis by a mitochondrial RNA polymerase.	got7fsn_ti														biological_process											owl:Class	
GO:0007229	biolink:NamedThing	integrin-mediated signaling pathway	A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	integrin-mediated signalling pathway													biological_process											owl:Class	
GO:0039617	biolink:NamedThing	T=3 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.	got7fsn_ti							bf	2012-07-18T02:07:40Z				VZ:806		cellular_component											owl:Class	
GO:0010486	biolink:NamedThing	manganese:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in).	got7fsn_ti	manganese:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0035530	biolink:NamedThing	chemokine (C-C motif) ligand 6 production	The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CCL6 production						bf	2010-05-07T10:21:15Z						biological_process											owl:Class	
GO:0071551	biolink:NamedThing	RIP homotypic interaction motif binding	Binding to a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases.	got7fsn_ti	RHIM binding						mah	2010-01-13T03:03:51Z						molecular_function											owl:Class	
GO:1901654	biolink:NamedThing	response to ketone	A response that results in a state of tolerance to ketone.	got7fsn_ti	process resulting in tolerance to ketone						pr	2012-11-20T10:55:47Z			GO:1990369			biological_process											owl:Class	
GO:0102872	biolink:NamedThing	1-16:0-2-18:2-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8361|EC:1.14.19.25		molecular_function											owl:Class	
GO:0070032	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).	got7fsn_ti	Vamp2-Snap25-Stx1a-Cplx1 complex|SNARE complex (Vamp2, Snap25, Stx1a, Cplx1)													cellular_component											owl:Class	
GO:0016239	biolink:NamedThing	positive regulation of macroautophagy	Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.	got7fsn_ti	up regulation of macroautophagy|up-regulation of macroautophagy|activation of macroautophagy|upregulation of macroautophagy|positive regulation of starvation-induced autophagy|stimulation of macroautophagy													biological_process											owl:Class	
GO:0016165	biolink:NamedThing	linoleate 13S-lipoxygenase activity	Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.	got7fsn_ti	lipoxydase activity|lipoxygenase activity|lionoleate:O2 oxidoreductase activity|lipoperoxidase activity|fat oxidase activity|lipoxidase activity|linoleate:oxygen 13-oxidoreductase activity|carotene oxidase activity											RHEA:22780|EC:1.13.11.12|MetaCyc:LIPOXYGENASE-RXN		molecular_function											owl:Class	
GO:0051934	biolink:NamedThing	catecholamine uptake involved in synaptic transmission	The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	got7fsn_ti	catecholamine neurotransmitter recycling|catecholamine reuptake during transmission of nerve impulse|catecholamine uptake during transmission of nerve impulse|catecholamine neurotransmitter import into neuron|catecholamine neurotransmitter reuptake|catecholamine neurotransmitter import into glial cell													biological_process											owl:Class	
GO:0010309	biolink:NamedThing	acireductone dioxygenase [iron(II)-requiring] activity	Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+).	got7fsn_ti	acireductone dioxygenase (Fe2+-requiring) activity|aci-reductone dioxygenase|2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase|1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)|ARD'|acireductone dioxygenase activity|E-2'|ARD1|1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity											Reactome:R-HSA-1237119|MetaCyc:R147-RXN|EC:1.13.11.54|KEGG_REACTION:R07364|RHEA:24504		molecular_function											owl:Class	
GO:0045227	biolink:NamedThing	capsule polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.	got7fsn_ti	capsule polysaccharide anabolism|capsule polysaccharide formation|capsular polysaccharide biosynthetic process|capsule polysaccharide biosynthesis|capsule polysaccharide synthesis|capsular polysaccharide biosynthesis													biological_process											owl:Class	
GO:0051653	biolink:NamedThing	spindle localization	Any process in which is the spindle is transported to, and/or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of spindle localization|spindle localisation													biological_process											owl:Class	
GO:0070582	biolink:NamedThing	theta DNA replication	A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.	got7fsn_ti	theta replication						mah	2009-04-22T02:54:50Z						biological_process											owl:Class	
GO:0000468	biolink:NamedThing	generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	got7fsn_ti	processing at B2													biological_process											owl:Class	
GO:0071164	biolink:NamedThing	RNA trimethylguanosine synthase activity	Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.	got7fsn_ti	snRNA methyltransferase activity|small nuclear RNA methyltransferase activity|cap hypermethylase activity						mah	2009-11-19T03:23:20Z						molecular_function											owl:Class	
GO:0052588	biolink:NamedThing	diacetyl reductase ((S)-acetoin forming) activity	Catalysis of the reaction: (S)-acetoin + NAD(+) = diacetyl + H(+) + NADH.	got7fsn_ti	(S)-acetoin dehydrogenase activity											EC:1.1.1.304|RHEA:27286|KEGG_REACTION:R09078|MetaCyc:RXN-11032		molecular_function											owl:Class	
GO:0019152	biolink:NamedThing	acetoin dehydrogenase activity	Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+.	got7fsn_ti	diacetyl reductase activity											EC:1.1.1.304|EC:1.1.1.303|KEGG_REACTION:R02343|MetaCyc:ACETOINDEHYDROG-RXN		molecular_function											owl:Class	
GO:0030784	biolink:NamedThing	3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.	got7fsn_ti	S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity											MetaCyc:2.1.1.116-RXN|EC:2.1.1.116|RHEA:17789		molecular_function											owl:Class	
GO:0042387	biolink:NamedThing	plasmatocyte differentiation	The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response.	got7fsn_ti														biological_process											owl:Class	
GO:0018166	biolink:NamedThing	C-terminal protein-tyrosinylation	The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase.	got7fsn_ti					See also the molecular function term 'tubulin-tyrosine ligase activity ; GO:0004835'.							RESID:AA0257		biological_process											owl:Class	
GO:0009010	biolink:NamedThing	sorbitol-6-phosphate 2-dehydrogenase activity	Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.	got7fsn_ti	ketosephosphate reductase activity|D-glucitol-6-phosphate dehydrogenase activity|sorbitol-6-P-dehydrogenase activity|D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity|D-sorbitol 6-phosphate dehydrogenase activity|D-sorbitol-6-phosphate dehydrogenase activity|glucitol-6-phosphate dehydrogenase activity											MetaCyc:SORB6PDEHYDROG-RXN|RHEA:19837|EC:1.1.1.140		molecular_function											owl:Class	
GO:0034043	biolink:NamedThing	5-hydroxymethyluracil DNA N-glycosylase activity	Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.	got7fsn_ti	5-hmU DNA N-glycosylase activity													molecular_function											owl:Class	
GO:0042727	biolink:NamedThing	flavin-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.	got7fsn_ti	flavin-containing compound biosynthesis|vitamin B2 and derivative biosynthesis|flavin-containing compound synthesis|flavin-containing compound anabolism|riboflavin and derivative biosynthetic process|riboflavin and derivative biosynthesis|vitamin B2 and derivative biosynthetic process|flavin-containing compound formation													biological_process											owl:Class	
GO:1990218	biolink:NamedThing	positive regulation by symbiont of abscisic acid levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-10T15:54:10Z						biological_process											owl:Class	
GO:0075343	biolink:NamedThing	modulation by symbiont of abscisic acid levels in host	The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term is intended for use in annotation of symbiont gene products. For host gene products that regulate abscisic acid levels in the host, consider annotating to 'regulation of abscisic acid mediated signaling ; GO:0009787' or 'regulation of abscisic acid biosynthetic process ; GO:0010115'.									biological_process											owl:Class	
GO:0102649	biolink:NamedThing	acetoacetyl-ACP synthase activity	Catalysis of the reaction: acetyl-CoA + malonyl-CoA + H+ + a holo-[acyl-carrier protein] <=> acetoacetyl-ACP + 2 coenzyme A + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-15810		molecular_function											owl:Class	
GO:0034802	biolink:NamedThing	branched-chain dodecylbenzene sulfonate monooxygenase activity	Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite.	got7fsn_ti												EC:1.14.13.-|UM-BBD_reactionID:r1079		molecular_function											owl:Class	
GO:0050295	biolink:NamedThing	steryl-beta-glucosidase activity	Catalysis of the reaction: cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol.	got7fsn_ti	steryl-b-glucosidase activity|cholesteryl-beta-D-glucoside glucohydrolase activity											KEGG_REACTION:R01460|RHEA:11956|EC:3.2.1.104|MetaCyc:STERYL-BETA-GLUCOSIDASE-RXN		molecular_function											owl:Class	
GO:0120278	biolink:NamedThing	negative regulation of cerebral blood circulation	Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.	got7fsn_ti	down regulation of cerebral blood circulation|inhibition of cerebral blood circulation|downregulation of cerebral blood circulation|negative regulation of telencephalon blood circulation|negative regulation of cerebrum blood circulation|down-regulation of cerebral blood circulation	https://github.com/geneontology/go-ontology/issues/20107					krc	2020-10-21T07:02:05Z						biological_process											owl:Class	
GO:1990566	biolink:NamedThing	I(KACh) inward rectifier potassium channel complex	An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signalling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.	got7fsn_ti	muscarinic potassium channel complex|GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex|Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex				Examples of this are KCNJ3 and KCNJ5 in human (Uniprot symbols P48549 and P48544) in PMID:9765280 inferred from orthology sequence evidence.		ame	2014-11-26T15:16:14Z						cellular_component											owl:Class	
GO:0004395	biolink:NamedThing	hexaprenyldihydroxybenzoate methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate.	got7fsn_ti	S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase activity|DHHB-Mt activity|DHHB methyltransferase activity|dihydroxyhexaprenylbenzoate methyltransferase activity|3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase activity											EC:2.1.1.114|RHEA:14121|MetaCyc:2.1.1.114-RXN		molecular_function											owl:Class	
GO:0008074	biolink:NamedThing	guanylate cyclase complex, soluble	Complex that possesses guanylate cyclase activity and is not bound to a membrane.	got7fsn_ti					See also the molecular function term 'guanylate cyclase activity ; GO:0004383'.									cellular_component											owl:Class	
GO:0102164	biolink:NamedThing	2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity	Catalysis of the reaction: 2-heptyl-4-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4-quinolone + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-11849|RHEA:37871|EC:1.14.13.182		molecular_function											owl:Class	
GO:0047433	biolink:NamedThing	branched-chain-2-oxoacid decarboxylase activity	Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2).	got7fsn_ti	(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)|branched-chain keto acid decarboxylase activity|branched-chain oxo acid decarboxylase activity|(3S)-3-methyl-2-oxopentanoate carboxy-lyase activity|BCKA|branched-chain alpha-keto acid decarboxylase activity											EC:4.1.1.72|RHEA:21108|KEGG_REACTION:R03894|MetaCyc:4.1.1.72-RXN		molecular_function											owl:Class	
GO:0015021	biolink:NamedThing	heparin-sulfate lyase activity	Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar.	got7fsn_ti	heparin-sulfate eliminase activity|heparitin-sulfate lyase activity|heparitinase I|heparin-sulphate lyase activity|heparitinase II|[heparan sulfate]-sulfate lyase activity											EC:4.2.2.8|MetaCyc:4.2.2.8-RXN		molecular_function											owl:Class	
GO:0035169	biolink:NamedThing	lymph gland plasmatocyte differentiation	The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.	got7fsn_ti	lymph gland plasmatocyte cell differentiation													biological_process											owl:Class	
GO:0022003	biolink:NamedThing	negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway	The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.	got7fsn_ti	fgf receptor signaling involved in inhibition of anterior neural cell fate of the neural plate|fgf receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in downregulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in down regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate													biological_process											owl:Class	
GO:0070122	biolink:NamedThing	isopeptidase activity	Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond).	got7fsn_ti														molecular_function											owl:Class	
GO:0102812	biolink:NamedThing	4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	Catalysis of the reaction: 4-coumaryl-CoA + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-(p-coumaroyl)-glucoside + coenzyme A.	got7fsn_ti												MetaCyc:RXN-8204		molecular_function											owl:Class	
GO:0000832	biolink:NamedThing	inositol hexakisphosphate 5-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.	got7fsn_ti	ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity											EC:2.7.4.21|KEGG_REACTION:R09087|MetaCyc:2.7.1.152-RXN|RHEA:12793		molecular_function											owl:Class	
GO:0071348	biolink:NamedThing	cellular response to interleukin-11	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.	got7fsn_ti	cellular response to IL-11						mah	2009-12-11T02:49:29Z						biological_process											owl:Class	
GO:0061970	biolink:NamedThing	maintenance of right sidedness	The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves.	got7fsn_ti							dph	2018-02-12T16:45:33Z						biological_process											owl:Class	
GO:1900597	biolink:NamedThing	demethylkotanin metabolic process	The chemical reactions and pathways involving demethylkotanin.	got7fsn_ti	demethylkotanin metabolism						di	2012-05-15T06:54:52Z						biological_process											owl:Class	
GO:0034865	biolink:NamedThing	2,4,4-trimethylpentanoate-CoA ligase activity	Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-.	got7fsn_ti												UM-BBD_reactionID:r1271		molecular_function											owl:Class	
GO:0005848	biolink:NamedThing	mRNA cleavage stimulating factor complex	A protein complex required for mRNA cleavage but not for poly(A) addition.	got7fsn_ti	cleavage stimulation factor activity|CstF complex													cellular_component											owl:Class	
GO:0061867	biolink:NamedThing	establishment of mitotic spindle asymmetry	The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure.	got7fsn_ti							dph	2017-04-28T12:39:13Z						biological_process											owl:Class	
GO:0042661	biolink:NamedThing	regulation of mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of mesoderm cell fate specification.	got7fsn_ti														biological_process											owl:Class	
GO:0015385	biolink:NamedThing	sodium:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).	got7fsn_ti	sodium:hydrogen antiporter activity|sodium/hydrogen antiporter activity|sodium:hydrogen exchange activity|pH-dependent sodium:hydrogen antiporter activity|sodium:hydrogen exchanger|pH-dependent sodium:proton antiporter activity										GO:0015502	Reactome:R-HSA-425983|Reactome:R-HSA-2872444|Reactome:R-HSA-425994|RHEA:29251|Reactome:R-HSA-426015|Reactome:R-HSA-425965|Reactome:R-HSA-2872463|Reactome:R-HSA-5661039|Reactome:R-HSA-5661086		molecular_function											owl:Class	
GO:0031482	biolink:NamedThing	myosin XII complex	A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.	got7fsn_ti														cellular_component											owl:Class	
GO:0050644	biolink:NamedThing	cis-p-coumarate glucosyltransferase activity	Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP.	got7fsn_ti	UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase activity											EC:2.4.1.209|RHEA:13129|MetaCyc:2.4.1.209-RXN|KEGG_REACTION:R05324		molecular_function											owl:Class	
GO:0060373	biolink:NamedThing	regulation of ventricular cardiac muscle cell membrane depolarization	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.	got7fsn_ti	regulation of ventricular cardiomyocyte membrane depolarization|electrocardiogram QRS complex|ventricular depolarization													biological_process											owl:Class	
GO:0030166	biolink:NamedThing	proteoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	got7fsn_ti	proteoglycan biosynthesis|proteoglycan anabolism|proteoglycan synthesis|proteoglycan formation													biological_process											owl:Class	
GO:0034933	biolink:NamedThing	1-hydroxy-6-methoxypyrene methyltransferase activity	Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX.	got7fsn_ti												UM-BBD_reactionID:r0956		molecular_function											owl:Class	
GO:0047501	biolink:NamedThing	(+)-neomenthol dehydrogenase activity	Catalysis of the reaction: (+)-neomenthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH.	got7fsn_ti	monoterpenoid dehydrogenase activity|(+)-neomenthol:NADP+ oxidoreductase activity											RHEA:23812|MetaCyc:+-NEOMENTHOL-DEHYDROGENASE-RXN|EC:1.1.1.208|KEGG_REACTION:R02548		molecular_function											owl:Class	
GO:1990051	biolink:NamedThing	activation of protein kinase C activity	Any process that initiates the activity of the inactive enzyme protein kinase C.	got7fsn_ti	PKC activation|protein kinase C activation						sl	2013-02-21T19:57:54Z						biological_process											owl:Class	
GO:0072498	biolink:NamedThing	embryonic skeletal joint development	The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.	got7fsn_ti							mah	2010-12-15T04:14:42Z						biological_process											owl:Class	
GO:0102480	biolink:NamedThing	5-fluorocytosine deaminase activity	Catalysis of the reaction: H+ + flucytosine + H2O <=> 5-fluorouracil + ammonium.	got7fsn_ti												MetaCyc:RXN-14129|EC:3.5.4.1		molecular_function											owl:Class	
GO:0009916	biolink:NamedThing	alternative oxidase activity	Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.	got7fsn_ti														molecular_function											owl:Class	
GO:0050524	biolink:NamedThing	coenzyme-B sulfoethylthiotransferase activity	Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.	got7fsn_ti	methyl coenzyme M reductase activity|methyl-coenzyme-M reductase activity|methyl-CoM reductase activity|2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase activity|coenzyme-B sulphoethylthiotransferase activity										GO:0018552	RHEA:12532|UM-BBD_reactionID:r0356|MetaCyc:METHYL-COM-HTP-RXN|EC:2.8.4.1|KEGG_REACTION:R04541		molecular_function											owl:Class	
GO:0016795	biolink:NamedThing	phosphoric triester hydrolase activity	Catalysis of the hydrolysis of a phosphoric triester.	got7fsn_ti												EC:3.1.8.-		molecular_function											owl:Class	
GO:0042578	biolink:NamedThing	phosphoric ester hydrolase activity	Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.	got7fsn_ti														molecular_function											owl:Class	
GO:0042317	biolink:NamedThing	penicillin catabolic process	The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti	penicillin catabolism|penicillin breakdown|penicillin degradation													biological_process											owl:Class	
GO:1990930	biolink:NamedThing	mRNA N1-methyladenosine dioxygenase activity	Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde.	got7fsn_ti	RNA N1-methyladenosine dioxygenase activity|RNA N(1)-methyladenosine dioxygenase activity	https://github.com/geneontology/go-ontology/issues/21812					sp	2016-03-10T08:06:47Z				RHEA:49516|EC:1.14.11.54		molecular_function											owl:Class	
GO:0030287	biolink:NamedThing	cell wall-bounded periplasmic space	The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.	got7fsn_ti	cell wall-enclosed periplasmic space|cell wall bounded periplasmic space|IWZ|inner wall zone													cellular_component											owl:Class	
GO:1900804	biolink:NamedThing	brevianamide F catabolic process	The chemical reactions and pathways resulting in the breakdown of brevianamide F.	got7fsn_ti	cyclo-L-Trp-L-Pro catabolism|tryptophan-proline diketopiperazine breakdown|cyclo-(Trp-Pro) breakdown|cyclo-L-tryptophanyl-L-proline breakdown|brevianamide F catabolism|L-prolyl-L-tryptophan anhydride degradation|L-prolyl-L-tryptophan anhydride catabolism|L-tryptophyl-L-proline cyclic anhydride breakdown|L-prolyl-L-tryptophan anhydride breakdown|cyclo-L-tryptophanyl-L-proline degradation|cyclo-L-Trp-L-Pro catabolic process|brevianamide F degradation|tryptophan-proline diketopiperazine catabolic process|cyclo-(Trp-Pro) catabolic process|tryptophan-proline diketopiperazine catabolism|cyclo-L-Trp-L-Pro breakdown|cyclo-L-Trp-L-Pro degradation|cyclo-L-tryptophanyl-L-proline catabolic process|tryptophan-proline diketopiperazine degradation|L-tryptophyl-L-proline cyclic anhydride catabolism|cyclo-L-tryptophanyl-L-proline catabolism|brevianamide F breakdown|L-tryptophyl-L-proline cyclic anhydride degradation|L-prolyl-L-tryptophan anhydride catabolic process|cyclo-(Trp-Pro) degradation|L-tryptophyl-L-proline cyclic anhydride catabolic process|cyclo-(Trp-Pro) catabolism						di	2012-06-04T09:52:41Z						biological_process											owl:Class	
GO:1900596	biolink:NamedThing	(+)-kotanin biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-kotanin.	got7fsn_ti	(+)-kotanin biosynthesis|(+)-kotanin synthesis|(+)-kotanin anabolism|(+)-kotanin formation						di	2012-05-15T06:54:47Z						biological_process											owl:Class	
GO:0046423	biolink:NamedThing	allene-oxide cyclase activity	Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate.	got7fsn_ti	(9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing)											KEGG_REACTION:R03402|RHEA:22592|EC:5.3.99.6|MetaCyc:ALLENE-OXIDE-CYCLASE-RXN		molecular_function											owl:Class	
GO:0018724	biolink:NamedThing	4-phenanthrol sulfotransferase activity	Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate.	got7fsn_ti	4-phenanthrol sulphotransferase activity											UM-BBD_reactionID:r0562		molecular_function											owl:Class	
GO:0035457	biolink:NamedThing	cellular response to interferon-alpha	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.	got7fsn_ti	cellular response to lymphoblastoid interferon|cellular response to interferon alfa-n3|cellular response to lymphoblast interferon|cellular response to interferon alfa-n1|cellular response to leukocyte interferon						bf	2010-04-16T11:08:29Z						biological_process											owl:Class	
GO:0018091	biolink:NamedThing	peptidyl-asparagine racemization	The racemization of peptidyl-asparagine.	got7fsn_ti											GO:0019127|GO:0018373	RESID:AA0196		biological_process											owl:Class	
GO:0002415	biolink:NamedThing	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa.	got7fsn_ti	immunoglobulin transcytosis mediated by pIgR|antibody transcytosis mediated by pIgR													biological_process											owl:Class	
GO:0047534	biolink:NamedThing	2-acetolactate mutase activity	Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate.	got7fsn_ti	acetolactate mutase activity|2-acetolactate methylmutase activity|acetohydroxy acid isomerase activity											RHEA:16361|EC:5.4.99.3|MetaCyc:2-ACETOLACTATE-MUTASE-RXN		molecular_function											owl:Class	
GO:0046693	biolink:NamedThing	sperm storage	The retention of sperm by a female following mating.	got7fsn_ti	storage of sperm|sequestering of sperm|sequestration of sperm|sperm sequestering|sperm retention|sperm sequestration|retention of sperm													biological_process											owl:Class	
GO:0051940	biolink:NamedThing	regulation of catecholamine uptake involved in synaptic transmission	Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.	got7fsn_ti	regulation of catecholamine neurotransmitter reuptake|regulation of catecholamine neurotransmitter uptake|regulation of catecholamine uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0070742	biolink:NamedThing	C2H2 zinc finger domain binding	Binding to a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.	got7fsn_ti							mah	2009-06-23T11:26:02Z						molecular_function											owl:Class	
GO:0061796	biolink:NamedThing	membrane addition at site of mitotic cytokinesis	A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.	got7fsn_ti							dph	2016-10-05T12:06:11Z						biological_process											owl:Class	
GO:0002081	biolink:NamedThing	outer acrosomal membrane	The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction.	got7fsn_ti					Note that this term is not a descendant of 'organelle outer membrane ; GO:0031968' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.									cellular_component											owl:Class	
GO:0035906	biolink:NamedThing	descending aorta development	The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.	got7fsn_ti							bf	2011-06-24T11:05:22Z						biological_process											owl:Class	
GO:0036361	biolink:NamedThing	racemase activity, acting on amino acids and derivatives	Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative.	got7fsn_ti							bf	2012-09-21T11:13:47Z						molecular_function											owl:Class	
GO:0018667	biolink:NamedThing	cyclohexanone monooxygenase activity	Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O.	got7fsn_ti	cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)|cyclohexanone 1,2-monooxygenase activity|cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing) activity|cyclohexanone oxygenase activity											EC:1.14.13.22|MetaCyc:CYCLOHEXANONE-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0166|RHEA:24068		molecular_function											owl:Class	
GO:0018705	biolink:NamedThing	1,2-dichloroethene reductive dehalogenase activity	Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride.	got7fsn_ti	1,2-dichloroethylene reductive dehalogenase activity											UM-BBD_enzymeID:e0272		molecular_function											owl:Class	
GO:0047502	biolink:NamedThing	(+)-sabinol dehydrogenase activity	Catalysis of the reaction: (+)-cis-sabinol + NAD(+) = (1S,5S)-sabinone + H(+) + NADH.	got7fsn_ti	(+)-cis-sabinol:NAD+ oxidoreductase activity|(+)-cis-sabinol dehydrogenase activity											MetaCyc:+-SABINOL-DEHYDROGENASE-RXN|RHEA:18329|KEGG_REACTION:R03745|EC:1.1.1.228		molecular_function											owl:Class	
GO:0051309	biolink:NamedThing	female meiosis chromosome separation	The process in which paired chromosomes are physically detached from each other during female meiosis.	got7fsn_ti	female meiosis chromosome resolution|chromosome separation during female meiosis													biological_process											owl:Class	
GO:0016321	biolink:NamedThing	female meiosis chromosome segregation	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.	got7fsn_ti														biological_process											owl:Class	
GO:0106340	biolink:NamedThing	tRNA (guanosine 32-2'-O)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 32 in tRNA.	got7fsn_ti							hjd	2020-11-05T22:52:49Z						molecular_function											owl:Class	
GO:0004665	biolink:NamedThing	prephenate dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADPH.	got7fsn_ti	prephenate:NADP+ oxidoreductase (decarboxylating)|prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity											RHEA:21640|KEGG_REACTION:R01730|EC:1.3.1.13|MetaCyc:PREPHENATE-DEHYDROGENASE-NADP+-RXN		molecular_function											owl:Class	
GO:1990643	biolink:NamedThing	cellular response to granulocyte colony-stimulating factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.	got7fsn_ti							sl	2015-02-11T19:22:44Z						biological_process											owl:Class	
GO:0032166	biolink:NamedThing	chlamydospore septin filament array	Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.	got7fsn_ti														cellular_component											owl:Class	
GO:0004346	biolink:NamedThing	glucose-6-phosphatase activity	Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.	got7fsn_ti	D-glucose-6-phosphate phosphohydrolase activity|glucose 6-phosphate phosphatase activity											RHEA:16689|KEGG_REACTION:R00303|Reactome:R-HSA-71825|Reactome:R-HSA-3282876|Reactome:R-HSA-3262512|Reactome:R-HSA-3266566|MetaCyc:GLUCOSE-6-PHOSPHATASE-RXN|Reactome:R-HSA-3274540|EC:3.1.3.9		molecular_function											owl:Class	
GO:0005666	biolink:NamedThing	RNA polymerase III complex	RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.	got7fsn_ti	DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III activity													cellular_component											owl:Class	
GO:0002356	biolink:NamedThing	peripheral B cell negative selection	Any process leading to negative selection of B cells in the periphery.	got7fsn_ti	peripheral B lymphocyte negative selection|peripheral B-cell negative selection|peripheral B-lymphocyte negative selection													biological_process											owl:Class	
GO:0004832	biolink:NamedThing	valine-tRNA ligase activity	Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H(+).	got7fsn_ti	valyl-transfer ribonucleic acid synthetase activity|L-valine:tRNAVal ligase (AMP-forming)|valine translase activity|valyl-transfer ribonucleate synthetase activity|valine transfer ribonucleate ligase activity|valyl-tRNA synthetase activity|valyl-transfer RNA synthetase activity											EC:6.1.1.9|Reactome:R-HSA-380199|Reactome:R-HSA-380042|KEGG_REACTION:R03665|MetaCyc:VALINE--TRNA-LIGASE-RXN|RHEA:10704		molecular_function											owl:Class	
GO:0097603	biolink:NamedThing	temperature-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).	got7fsn_ti	heat-activated ion channel activity|temperature-activated ion channel activity|temperature gated ion channel activity|temperature-dependent ion channel activity						pr	2014-05-12T13:10:42Z						molecular_function											owl:Class	
GO:0000438	biolink:NamedThing	core TFIIH complex portion of holo TFIIH complex	The core TFIIH complex when it is part of the general transcription factor TFIIH.	got7fsn_ti	SSL2-core TFIIH complex portion of holo TFIIH complex										GO:0000443			cellular_component											owl:Class	
GO:0046033	biolink:NamedThing	AMP metabolic process	The chemical reactions and pathways involving AMP, adenosine monophosphate.	got7fsn_ti	adenylate forming enzyme activity|AMP metabolism													biological_process											owl:Class	
GO:0072230	biolink:NamedThing	metanephric proximal straight tubule development	The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.	got7fsn_ti	metanephric S3 development						mah	2010-03-18T03:38:53Z						biological_process											owl:Class	
GO:0072020	biolink:NamedThing	proximal straight tubule development	The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.	got7fsn_ti	S3 development						mah	2010-01-25T02:36:14Z						biological_process											owl:Class	
GO:1902093	biolink:NamedThing	positive regulation of flagellated sperm motility	Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.	got7fsn_ti	up-regulation of sperm motility|up regulation of sperm movement|activation of sperm movement|activation of sperm motility|positive regulation of sperm movement|positive regulation of sperm motility|up regulation of sperm motility|up-regulation of sperm movement|upregulation of sperm motility|upregulation of sperm movement						bf	2013-04-29T09:15:25Z						biological_process											owl:Class	
GO:1901317	biolink:NamedThing	regulation of flagellated sperm motility	Any process that modulates the frequency, rate or extent of flagellated sperm motility.	got7fsn_ti	regulation of sperm motility|regulation of sperm movement						hjd	2012-08-22T20:50:14Z						biological_process											owl:Class	
GO:0047761	biolink:NamedThing	butyrate kinase activity	Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H(+).	got7fsn_ti	ATP:butanoate 1-phosphotransferase activity											MetaCyc:BUTYRATE-KINASE-RXN|KEGG_REACTION:R01688|RHEA:13585|EC:2.7.2.7		molecular_function											owl:Class	
GO:0004792	biolink:NamedThing	thiosulfate sulfurtransferase activity	Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate.	got7fsn_ti	rhodanese activity|thiosulfate:cyanide sulfurtransferase activity|rhodanase activity|thiosulphate sulphurtransferase activity|thiosulfate cyanide transsulfurase activity|thiosulfate thiotransferase activity											MetaCyc:THIOSULFATE-SULFURTRANSFERASE-RXN|KEGG_REACTION:R01931|EC:2.8.1.1|RHEA:16881|Reactome:R-HSA-9013198		molecular_function											owl:Class	
GO:0042262	biolink:NamedThing	DNA protection	Any process in which DNA is protected from damage by, for example, oxidative stress.	got7fsn_ti														biological_process											owl:Class	
GO:0010403	biolink:NamedThing	pectic arabinogalactan I metabolic process	The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I.	got7fsn_ti	pectic arabinogalactan I metabolism													biological_process											owl:Class	
GO:0039621	biolink:NamedThing	T=13 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=13 symmetry. The T=13 capsid is composed of 12 pentameric and 120 hexameric capsomeres.	got7fsn_ti							bf	2012-07-18T02:18:59Z				VZ:260		cellular_component											owl:Class	
GO:0034786	biolink:NamedThing	9-fluorenone-3,4-dioxygenase activity	Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone.	got7fsn_ti												UM-BBD_reactionID:r1039		molecular_function											owl:Class	
GO:0070821	biolink:NamedThing	tertiary granule membrane	The lipid bilayer surrounding a tertiary granule.	got7fsn_ti							mah	2009-07-20T03:59:41Z						cellular_component											owl:Class	
GO:0045430	biolink:NamedThing	chalcone isomerase activity	Catalysis of the reaction: a chalcone = a flavanone.	got7fsn_ti	chalcone-flavanone isomerase activity|chalcone--flavonone isomerase activity|flavanone lyase (decyclizing)											MetaCyc:CHALCONE-ISOMERASE-RXN|EC:5.5.1.6		molecular_function											owl:Class	
GO:0034854	biolink:NamedThing	4,4-dimethyl-3-oxopentanoate decarboxylase activity	Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2.	got7fsn_ti												UM-BBD_reactionID:r1280		molecular_function											owl:Class	
GO:0035709	biolink:NamedThing	memory T cell activation	The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti							bf	2011-03-02T03:03:02Z						biological_process											owl:Class	
GO:0097629	biolink:NamedThing	extrinsic component of omegasome membrane	The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to omegasome membrane|omegasome peripheral membrane													cellular_component											owl:Class	
GO:0140396	biolink:NamedThing	5'-hydroxyaverantin dehydrogenase activity	Catalyzes the reaction: (1'S,5'S)-hydroxyaverantin + NAD(+) <=> 5'-oxoaverantin + NADH.	got7fsn_ti							pg	2019-11-29T08:56:49Z				RHEA:35475|EC:1.1.1.352		molecular_function											owl:Class	
GO:0070671	biolink:NamedThing	response to interleukin-12	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.	got7fsn_ti	response to IL-12						mah	2009-05-29T10:02:31Z						biological_process											owl:Class	
GO:0071286	biolink:NamedThing	cellular response to magnesium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.	got7fsn_ti							mah	2009-12-10T04:05:50Z						biological_process											owl:Class	
GO:0032026	biolink:NamedThing	response to magnesium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0032170	biolink:NamedThing	pseudohyphal septin ring	A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0080150	biolink:NamedThing	S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity	Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine.	got7fsn_ti	S-adenosyl-L-methionine:benzoate carboxyl methyltransferase activity						dhl	2010-03-26T04:19:39Z				RHEA:36099|MetaCyc:RXN-6722		molecular_function											owl:Class	
GO:0080172	biolink:NamedThing	petal epidermis patterning	The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis.	got7fsn_ti							dhl	2011-04-25T04:44:06Z						biological_process											owl:Class	
GO:0009072	biolink:NamedThing	aromatic amino acid family metabolic process	The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).	got7fsn_ti	aromatic amino acid family metabolism													biological_process											owl:Class	
GO:0043973	biolink:NamedThing	histone H3-K4 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone.	got7fsn_ti	histone H3 acetylation at K4|histone H3K4 acetylation													biological_process											owl:Class	
GO:0006476	biolink:NamedThing	protein deacetylation	The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti	protein amino acid deacetylation													biological_process											owl:Class	
GO:1990247	biolink:NamedThing	N6-methyladenosine-containing RNA binding	Binding to an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs.	got7fsn_ti							sp	2013-12-04T06:55:29Z						molecular_function											owl:Class	
GO:0098650	biolink:NamedThing	peptidyl-proline 4-dioxygenase binding	Binding to a peptidyl-proline 4-dioxygenase.	got7fsn_ti														molecular_function											owl:Class	
GO:0044204	biolink:NamedThing	host cell nuclear matrix	The dense fibrillar network lying on the inner side of the host nuclear membrane.	got7fsn_ti							jl	2009-10-21T11:15:36Z						cellular_component											owl:Class	
GO:0003356	biolink:NamedThing	regulation of cilium beat frequency	Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium.	got7fsn_ti	regulation of flagellum beat frequency|regulation of microtubule-based flagellum beat frequency				Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-12-03T10:27:12Z			GO:0036144			biological_process											owl:Class	
GO:0003352	biolink:NamedThing	regulation of cilium movement	Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.	got7fsn_ti	regulation of flagellum movement|regulation of flagellar movement|regulation of microtubule-based flagellum movement				Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-12-03T10:12:00Z			GO:1900172			biological_process											owl:Class	
GO:0052064	biolink:NamedThing	induction by symbiont of defense-related host reactive oxygen species production	The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by symbiont of defense-related host ROI production|induction by symbiont of defense-related host reactive oxidative species production|activation by symbiont of defense-related host respiratory burst|activation by symbiont of defense-related host reactive oxygen intermediate production|induction by symbiont of defense-related host metabolic burst|positive regulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|upregulation by symbiont of defense-related host reactive oxygen species production|induction by symbiont of defense-related host oxidative burst|induction by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|stimulation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host metabolic burst|up-regulation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host reactive oxidative species production|up regulation by symbiont of defense-related host reactive oxygen species production|positive regulation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host ROS production|induction by symbiont of defense-related host AOS production|activation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host oxidative burst|induction by symbiont of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|induction by symbiont of defense-related host active oxygen species production										GO:0052369|GO:0052264|GO:0052348			biological_process											owl:Class	
GO:0000164	biolink:NamedThing	protein phosphatase type 1 complex	A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0102960	biolink:NamedThing	momilactone-A synthase activity	Catalysis of the reaction: 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P) = momilactone A + H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-9290|EC:1.1.1.295|RHEA:25367		molecular_function											owl:Class	
GO:0051211	biolink:NamedThing	anisotropic cell growth	The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell.	got7fsn_ti	non-isotropic cell growth													biological_process											owl:Class	
GO:0047590	biolink:NamedThing	5-dehydro-2-deoxygluconokinase activity	Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.	got7fsn_ti	5-keto-2-deoxyglucono kinase (phosphorylating)|DKH kinase activity|ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase activity|5-keto-2-deoxygluconokinase activity											RHEA:13497|MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN|EC:2.7.1.92		molecular_function											owl:Class	
GO:0015016	biolink:NamedThing	[heparan sulfate]-glucosamine N-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine.	got7fsn_ti	3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity|3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity|heparin N-deacetylase/N-sulfotransferase activity|PAPS:N-desulfoheparin sulfotransferase activity|heparitin sulfotransferase activity|heparan sulfate N-deacetylase/N-sulfotransferase activity|[heparan sulphate]-glucosamine N-sulphotransferase activity|heparitin N-sulphotransferase activity|heparin-glucosamine N-sulfotransferase activity|N-HSST activity|N-heparan sulfate sulfotransferase activity|N-desulfoheparin sulfotransferase activity|heparitin N-sulfotransferase activity|PAPS:DSH sulfotransferase activity|3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity|heparan sulfate N-sulfotransferase activity|heparin N-deacetylase/N-sulphotransferase activity|heparan sulfate 2-N-sulfotransferase activity|heparin N-sulfotransferase activity|glucosaminyl N-deacetylase/N-sulfotransferase activity|desulfoheparin sulfotransferase activity				Note that this activity includes EC:2.8.2.12 (deleted from EC).						GO:0051910|GO:0004393|GO:0015022	Reactome:R-HSA-2022860|RHEA:21980|EC:2.8.2.8|MetaCyc:HEPARITIN-SULFOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0001849	biolink:NamedThing	complement component C1q complex binding	Binding to a C1q complex, a component of the classical complement cascade.	got7fsn_ti														molecular_function											owl:Class	
GO:0046481	biolink:NamedThing	digalactosyldiacylglycerol synthase activity	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H(+) + UDP.	got7fsn_ti	UDP-galactose-dependent DGDG synthase activity|DGD1|DGDG synthase activity|DGD2|UDP-galactose:MGDG galactosyltransferase activity|UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase activity|UDP-galactose-dependent digalactosyldiacylglycerol synthase activity											EC:2.4.1.241|Wikipedia:Digalactosyldiacylglycerol_synthase|KEGG_REACTION:R04469|MetaCyc:RXN-1225|RHEA:10520		molecular_function											owl:Class	
GO:0018463	biolink:NamedThing	6-hydroxyhexanoate dehydrogenase activity	Catalysis of the reaction: 6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + H(+) + NADH.	got7fsn_ti	6-hydroxyhexanoate:NAD+ oxidoreductase activity											MetaCyc:6-HYDROXYHEXANOATE-OXIDATION-RXN|RHEA:14225|EC:1.1.1.258|KEGG_REACTION:R05283|UM-BBD_reactionID:r0174		molecular_function											owl:Class	
GO:0047853	biolink:NamedThing	difructose-anhydride synthase activity	Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose.	got7fsn_ti	inulobiose hydrolase activity|bis-D-fructose 2',1:2,1'-dianhydride fructohydrolase activity											EC:3.2.1.134|MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN|RHEA:15041		molecular_function											owl:Class	
GO:0007302	biolink:NamedThing	nurse cell nucleus anchoring	Attachment of the nurse cell nucleus to the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0051647	biolink:NamedThing	nucleus localization	Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	nucleus localisation|cell nucleus localization|establishment and maintenance of nucleus localization|localization of nucleus													biological_process											owl:Class	
GO:0080083	biolink:NamedThing	beta-gentiobiose beta-glucosidase activity	Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose.	got7fsn_ti							dhl	2009-04-14T04:10:14Z						molecular_function											owl:Class	
GO:0007113	biolink:NamedThing	endomitotic cell cycle	A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.	got7fsn_ti	endomitosis				Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins.							Wikipedia:Mitosis#Endomitosis		biological_process											owl:Class	
GO:1990796	biolink:NamedThing	photoreceptor cell terminal bouton	A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light.	got7fsn_ti							sl	2015-07-09T21:33:40Z						cellular_component											owl:Class	
GO:0006642	biolink:NamedThing	triglyceride mobilization	The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism.	got7fsn_ti	triacylglycerol mobilization													biological_process											owl:Class	
GO:0006641	biolink:NamedThing	triglyceride metabolic process	The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.	got7fsn_ti	triglyceride metabolism|triacylglycerol metabolic process|triacylglycerol metabolism													biological_process											owl:Class	
GO:0034474	biolink:NamedThing	U2 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U2 snRNA molecule.	got7fsn_ti	U2 snRNA 3' end processing													biological_process											owl:Class	
GO:0032579	biolink:NamedThing	apical lamina of hyaline layer	A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms.	got7fsn_ti														cellular_component											owl:Class	
GO:1901361	biolink:NamedThing	organic cyclic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organic cyclic compound.	got7fsn_ti	organic cyclic compound degradation|organic cyclic compound catabolism|organic cyclic compound breakdown						bf	2012-09-14T09:05:04Z						biological_process											owl:Class	
GO:0030570	biolink:NamedThing	pectate lyase activity	Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends.	got7fsn_ti	pectate transeliminase activity|polygalacturonate lyase activity|PPase-N activity|endopectin methyltranseliminase activity|alpha-1,4-D-endopolygalacturonic acid lyase activity|polygalacturonic acid lyase activity|polygalacturonic transeliminase activity|pectin trans-eliminase activity|(1->4)-alpha-D-galacturonan lyase activity|polygalacturonic acid trans-eliminase activity|pectic acid transeliminase activity|pectic acid lyase activity|endogalacturonate transeliminase activity|endo-alpha-1,4-polygalacturonic acid lyase activity|PGA lyase activity|pectic lyase activity											MetaCyc:4.2.2.2-RXN|EC:4.2.2.2		molecular_function											owl:Class	
GO:0003942	biolink:NamedThing	N-acetyl-gamma-glutamyl-phosphate reductase activity	Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+.	got7fsn_ti	N-acetylglutamic gamma-semialdehyde dehydrogenase activity|reductase, acetyl-gamma-glutamyl phosphate|N-acetyl-L-glutamate gamma-semialdehyde:NADP oxidoreductase (phosphorylating)|N-acetylglutamate 5-semialdehyde dehydrogenase activity|N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)|NAGSA dehydrogenase activity|N-acetyl-glutamate semialdehyde dehydrogenase activity											RHEA:21588|MetaCyc:N-ACETYLGLUTPREDUCT-RXN|EC:1.2.1.38		molecular_function											owl:Class	
GO:0017014	biolink:NamedThing	protein nitrosylation	The covalent addition of a nitric oxide group to an amino acid within a protein.	got7fsn_ti	protein amino acid nitrosylation													biological_process											owl:Class	
GO:0008716	biolink:NamedThing	D-alanine-D-alanine ligase activity	Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H(+) + phosphate.	got7fsn_ti	D-Ala-D-Ala synthetase activity|D-alanyl-D-alanine synthetase activity|D-alanylalanine synthetase activity|alanine:alanine ligase (ADP-forming) activity|D-alanine:D-alanine ligase (ADP-forming)|alanylalanine synthetase activity											MetaCyc:DALADALALIG-RXN|RHEA:11224|EC:6.3.2.4|KEGG_REACTION:R01150		molecular_function											owl:Class	
GO:0018407	biolink:NamedThing	peptidyl-thyronine iodination to form 3',3'',5'-triiodo-L-thyronine	The iodination of peptidyl-thyronine to form peptidyl-3',3'',5'-triiodo-L-thyronine (triiodothyronine).	got7fsn_ti	peptidyl-thyronine iodination to form triiodothyronine											RESID:AA0177		biological_process											owl:Class	
GO:0050133	biolink:NamedThing	N6-hydroxylysine O-acetyltransferase activity	Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA.	got7fsn_ti	N6-hydroxylysine acetylase activity|N(6)-hydroxylysine acetylase activity|acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase activity|N6-hydroxylysine:acetyl CoA N6-transacetylase activity|acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase activity											KEGG_REACTION:R03168|MetaCyc:N6-HYDROXYLYSINE-O-ACETYLTRANSFERASE-RXN|RHEA:22388|EC:2.3.1.102		molecular_function											owl:Class	
GO:0002481	biolink:NamedThing	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	got7fsn_ti	TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class Ib|exogenous peptide antigen processing and presentation via MHC class Ib, TAP-dependent|TAP-dependent exogenous peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0047700	biolink:NamedThing	beta-glucoside kinase activity	Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.	got7fsn_ti	beta-D-glucoside kinase (phosphorylating)|b-glucoside kinase activity|ATP:cellobiose 6-phosphotransferase activity											EC:2.7.1.85|MetaCyc:BETA-GLUCOSIDE-KINASE-RXN|RHEA:21944		molecular_function											owl:Class	
GO:0102985	biolink:NamedThing	delta12-fatty-acid desaturase activity	Catalysis of the reaction: oleoyl-CoA + O2 + a reduced electron acceptor <=> linoleoyl-CoA + 2 H2O + an oxidized electron acceptor. This microsomal enzyme introduces a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9.	got7fsn_ti												RHEA:25856|MetaCyc:RXN-9601|EC:1.14.19.6		molecular_function											owl:Class	
GO:0061786	biolink:NamedThing	peptidoglycan stem peptide endopeptidase activity	A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan.	got7fsn_ti							dph	2016-09-07T16:47:04Z						molecular_function											owl:Class	
GO:0052654	biolink:NamedThing	L-leucine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid.	got7fsn_ti	L-leucine aminotransferase activity											MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN|EC:2.6.1.42|KEGG_REACTION:R01090		molecular_function											owl:Class	
GO:0008849	biolink:NamedThing	enterochelin esterase activity	Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+.	got7fsn_ti	enterobactin esterase activity											MetaCyc:RXN0-1661|RHEA:28018		molecular_function											owl:Class	
GO:0102414	biolink:NamedThing	quercetin-3-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin-3-gentiobioside + UDP.	got7fsn_ti												MetaCyc:RXN-13797		molecular_function											owl:Class	
GO:0102703	biolink:NamedThing	camphene synthase activity	Catalysis of the reaction: geranyl diphosphate <=> (-)-camphene + diphosphoric acid.	got7fsn_ti												RHEA:25484|EC:4.2.3.117|MetaCyc:RXN-5142		molecular_function											owl:Class	
GO:0045341	biolink:NamedThing	MHC class I biosynthetic process	The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I.	got7fsn_ti	MHC class I anabolism|MHC class I synthesis|major histocompatibility complex class I biosynthetic process|major histocompatibility complex class I biosynthesis|MHC class I formation|MHC class I biosynthesis													biological_process											owl:Class	
GO:0021665	biolink:NamedThing	rhombomere 5 structural organization	The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti	rhombomere 5 structural organisation													biological_process											owl:Class	
GO:0043965	biolink:NamedThing	suppression by symbiont of host adenylate cyclase-mediated signal transduction	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of host adenylate cyclase-mediated signal transduction													biological_process											owl:Class	
GO:0015849	biolink:NamedThing	organic acid transport	The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0060909	biolink:NamedThing	regulation of DNA replication initiation involved in plasmid copy number maintenance	Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.	got7fsn_ti							dph	2009-09-04T02:51:48Z						biological_process											owl:Class	
GO:0008437	biolink:NamedThing	thyrotropin-releasing hormone activity	The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.	got7fsn_ti	thyrotropin releasing hormone activity|TRH activity													molecular_function											owl:Class	
GO:0043903	biolink:NamedThing	regulation of biological process involved in symbiotic interaction	Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.	got7fsn_ti	regulation of symbiotic process|regulation of symbiosis, encompassing mutualism through parasitism|regulation of interspecies interactions between organisms	https://github.com/geneontology/go-ontology/issues/20191|https://github.com/geneontology/go-ontology/issues/19028			regulation of interspecies interactions between organisms									biological_process											owl:Class	
GO:0035408	biolink:NamedThing	histone H3-T6 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone.	got7fsn_ti							bf	2010-03-24T10:12:51Z						biological_process											owl:Class	
GO:0033094	biolink:NamedThing	butane-1,4-diamine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O.	got7fsn_ti	PAT activity|putrescine:alpha-ketoglutarate aminotransferase activity|putrescine-alpha-ketoglutarate transaminase activity|putrescine aminotransferase activity|putrescine transaminase activity|putrescine:2-oxoglutarate aminotransferase activity|YgjG											EC:2.6.1.82|RHEA:12268|MetaCyc:2.6.1.82-RXN		molecular_function											owl:Class	
GO:0036139	biolink:NamedThing	peptidyl-histidine dioxygenase activity	Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2.	got7fsn_ti							bf	2012-03-07T09:26:54Z						molecular_function											owl:Class	
GO:0097408	biolink:NamedThing	fibrillary inclusion	Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra.	got7fsn_ti							pr	2012-10-31T13:53:58Z				NIF_Subcellular:sao967812059		cellular_component											owl:Class	
GO:0035882	biolink:NamedThing	defecation rhythm	The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.	got7fsn_ti	DMP|defecation behavior|defecation cycle|defecation motor program						bf	2011-06-06T11:36:35Z						biological_process											owl:Class	
GO:0047115	biolink:NamedThing	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.	got7fsn_ti	dihydrodiol dehydrogenase activity|trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase activity											EC:1.3.1.20|MetaCyc:1.3.1.20-RXN|RHEA:16729		molecular_function											owl:Class	
GO:0003830	biolink:NamedThing	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R.	got7fsn_ti	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|GnTIII activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity|uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III|uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase III activity|N-acetylglucosaminyltransferase III activity|UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity											MetaCyc:2.4.1.144-RXN|RHEA:15509|EC:2.4.1.144|Reactome:R-HSA-975926		molecular_function											owl:Class	
GO:0102693	biolink:NamedThing	UDP-glucose:kinetin 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + kinetin-7-N-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-4731		molecular_function											owl:Class	
GO:0102374	biolink:NamedThing	ursolic aldehyde 28-monooxygenase activity	Catalysis of the reaction: ursolic aldehyde + NADPH + O2 + H+ <=> ursolic acid + NADP + H2O.	got7fsn_ti												EC:1.14.14.126|MetaCyc:RXN-13502		molecular_function											owl:Class	
GO:0097132	biolink:NamedThing	cyclin D2-CDK6 complex	A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:56:34Z						cellular_component											owl:Class	
GO:0006207	biolink:NamedThing	'de novo' pyrimidine nucleobase biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.	got7fsn_ti	'de novo' pyrimidine base synthesis|'de novo' pyrimidine base formation|'de novo' pyrimidine base anabolism|'de novo' pyrimidine base biosynthesis|'de novo' pyrimidine base biosynthetic process													biological_process											owl:Class	
GO:0019856	biolink:NamedThing	pyrimidine nucleobase biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.	got7fsn_ti	pyrimidine base synthesis|pyrimidine base biosynthetic process|pyrimidine base biosynthesis|pyrimidine base anabolism|pyrimidine base formation													biological_process											owl:Class	
GO:0050139	biolink:NamedThing	nicotinate-N-glucosyltransferase activity	Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.	got7fsn_ti	nicotinate glucosyltransferase activity|UDP-glucose:nicotinic acid-N-glucosyltransferase activity|UDP-glucose:nicotinate N-glucosyltransferase activity|uridine diphosphoglucose-nicotinate N-glucosyltransferase activity|UDPglucose:nicotinate N-glucosyltransferase activity											MetaCyc:NICOTINATE-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R01722|RHEA:19437|EC:2.4.1.196		molecular_function											owl:Class	
GO:0035483	biolink:NamedThing	gastric emptying	The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.	got7fsn_ti							bf	2010-04-23T10:51:33Z						biological_process											owl:Class	
GO:0090470	biolink:NamedThing	shoot organ boundary specification	The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained.	got7fsn_ti							tb	2012-09-24T16:22:03Z						biological_process											owl:Class	
GO:0032152	biolink:NamedThing	meiotic septin complex	A heterooligomeric septin complex that acts during meiotic cell division.	got7fsn_ti														cellular_component											owl:Class	
GO:0050356	biolink:NamedThing	tropine dehydrogenase activity	Catalysis of the reaction: NADP(+) + tropine = H(+) + NADPH + tropinone.	got7fsn_ti	tropine:NADP+ 3alpha-oxidoreductase activity											MetaCyc:TROPINE-DEHYDROGENASE-RXN|RHEA:18357|EC:1.1.1.206|KEGG_REACTION:R02832		molecular_function											owl:Class	
GO:0044029	biolink:NamedThing	hypomethylation of CpG island	An decrease in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.	got7fsn_ti	DNA hypomethylation of CpG island													biological_process											owl:Class	
GO:0052633	biolink:NamedThing	isocitrate hydro-lyase (cis-aconitate-forming) activity	Catalysis of the reaction: cis-aconitate + H2O = isocitrate.	got7fsn_ti	citrate(isocitrate) hydro-lyase activity|citrate hydro-lyase activity|citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|aconitate hydratase activity|cis-aconitase activity											MetaCyc:ACONITATEHYDR-RXN|KEGG_REACTION:R01900|RHEA:22144		molecular_function											owl:Class	
GO:0060999	biolink:NamedThing	positive regulation of dendritic spine development	Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-01-20T09:27:21Z						biological_process											owl:Class	
GO:0046408	biolink:NamedThing	chlorophyll synthetase activity	Catalysis of the reaction: chlorophyllide a + 2 H(+) + phytyl diphosphate = chlorophyll a + diphosphate.	got7fsn_ti	chlorophyllide-a:phytyl-diphosphate phytyltransferase activity|chlorophyll synthase activity										GO:0043787	MetaCyc:RXN1F-66|EC:2.5.1.62|KEGG_REACTION:R06284|RHEA:17317		molecular_function											owl:Class	
GO:0015272	biolink:NamedThing	ATP-activated inward rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.	got7fsn_ti												Reactome:R-HSA-5683209		molecular_function											owl:Class	
GO:0047403	biolink:NamedThing	lacto-N-biosidase activity	Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc.	got7fsn_ti	oligosaccharide lacto-N-biosylhydrolase activity											RHEA:21568|EC:3.2.1.140		molecular_function											owl:Class	
GO:0050157	biolink:NamedThing	ornithine racemase activity	Catalysis of the reaction: L-ornithine = D-ornithine.	got7fsn_ti												RHEA:11584|EC:5.1.1.12|MetaCyc:ORNITHINE-RACEMASE-RXN		molecular_function											owl:Class	
GO:0018684	biolink:NamedThing	2,5-diketocamphane 1,2-monooxygenase	Catalysis of the reaction: 1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H+ + H2O.	got7fsn_ti	camphor ketolactonase I activity|(+)-camphor,reduced-rubredoxin:oxygen oxidoreductase (1,2-lactonizing)|2,5-diketocamphane lactonizing enzyme activity|camphor 1,2-monooxygenase activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.14.15.2.							EC:1.14.14.108|MetaCyc:CAMPHOR-12-MONOOXYGENASE-RXN|RHEA:34415|UM-BBD_enzymeID:e0302		molecular_function											owl:Class	
GO:0000395	biolink:NamedThing	mRNA 5'-splice site recognition	Recognition of the intron 5'-splice site by components of the assembling spliceosome.	got7fsn_ti	spliceosomal CC complex formation|U12-type nuclear mRNA 5' splice site recognition|spliceosomal E complex formation|spliceosomal commitment complex biosynthesis|U2-type nuclear mRNA 5'-splice site recognition|spliceosomal commitment complex formation|U2-type nuclear mRNA 5' splice site recognition|nuclear mRNA 5' splice site recognition|spliceosomal E complex biosynthesis|U12-type nuclear mRNA 5'-splice site recognition|spliceosomal CC complex biosynthesis|nuclear mRNA 5'-splice site recognition				Note that this step represents formation of the Commitment Complex (CC, in yeast) or the E complex (mammalian).						GO:0000368|GO:0000369			biological_process											owl:Class	
GO:0061995	biolink:NamedThing	ATP-dependent protein-DNA complex displacement activity	An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis.	got7fsn_ti	ATP-dependent protein-nucleic acid complex displacement activity	https://github.com/geneontology/go-ontology/issues/21612					dph	2018-02-16T15:46:47Z			GO:0061994			molecular_function											owl:Class	
GO:0071588	biolink:NamedThing	hydrogen peroxide mediated signaling pathway	A series of molecular signals mediated by the detection of hydrogen peroxide (H2O2).	got7fsn_ti	H2O2 mediated signaling pathway|hydrogen peroxide mediated signalling pathway						mah	2010-01-29T11:18:58Z						biological_process											owl:Class	
GO:0070732	biolink:NamedThing	spindle envelope	An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase.	got7fsn_ti							mah	2009-06-18T12:00:59Z						cellular_component											owl:Class	
GO:0008789	biolink:NamedThing	altronate dehydratase activity	Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.	got7fsn_ti	D-altronate hydro-lyase activity|D-altronate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)											KEGG_REACTION:R01540|RHEA:15957|EC:4.2.1.7|MetaCyc:ALTRODEHYDRAT-RXN		molecular_function											owl:Class	
GO:0060858	biolink:NamedThing	vesicle-mediated transport involved in floral organ abscission	The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.	got7fsn_ti	membrane trafficking involved in floral organ shedding						dph	2009-08-12T03:48:54Z						biological_process											owl:Class	
GO:0002953	biolink:NamedThing	5'-deoxynucleotidase activity	Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0004836	biolink:NamedThing	tyramine-beta hydroxylase activity	Catalysis of the hydroxylation of tyramine to form octopamine.	got7fsn_ti														molecular_function											owl:Class	
GO:0035627	biolink:NamedThing	ceramide transport	The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.	got7fsn_ti							bf	2010-12-10T10:02:16Z						biological_process											owl:Class	
GO:0032636	biolink:NamedThing	interleukin-7 production	The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-7 secretion|IL-7 production|interleukin-7 biosynthetic process										GO:0042227|GO:0072605			biological_process											owl:Class	
GO:0071959	biolink:NamedThing	maintenance of mitotic sister chromatid cohesion, arms	The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.	got7fsn_ti	maintenance of mitotic sister chromatin cohesion along arms|maintenance of sister chromatin cohesion along arms at mitosis						mah	2011-06-01T04:08:43Z						biological_process											owl:Class	
GO:0050609	biolink:NamedThing	phosphonate dehydrogenase activity	Catalysis of the reaction: H(2)O + NAD(+) + phosphonate = 2 H(+) + NADH + phosphate.	got7fsn_ti	phosphonate:NAD+ oxidoreductase activity|NAD:phosphite oxidoreductase activity|NAD-dependent phosphite dehydrogenas activity|phosphite dehydrogenase activity											RHEA:13173|MetaCyc:1.20.1.1-RXN|EC:1.20.1.1|KEGG_REACTION:R05746|UM-BBD_reactionID:r1055		molecular_function											owl:Class	
GO:0051596	biolink:NamedThing	methylglyoxal catabolic process	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.	got7fsn_ti	methylglyoxal catabolism|methylglyoxal breakdown|methylglyoxal degradation											MetaCyc:Methylglyoxal-Detoxification|MetaCyc:METHGLYUT-PWY		biological_process											owl:Class	
GO:0044774	biolink:NamedThing	mitotic DNA integrity checkpoint signaling	A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.	got7fsn_ti	intracellular signaling cascade involved in mitotic DNA integrity checkpoint|signal transduction involved in mitotic DNA integrity checkpoint|intracellular signal transduction involved in topo II checkpoint|intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling chain involved in mitotic DNA integrity checkpoint|intracellular signaling cascade involved in topo II checkpoint|mitotic DNA integrity checkpoint|intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint|signal transduction via intracellular signaling cascade involved in topo II checkpoint|intracellular signaling pathway involved in mitotic DNA integrity checkpoint|intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint|intracellular signal transduction pathway involved in topo II checkpoint|mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signal transduction pathway involved in topoisomerase II checkpoint|intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling pathway involved in topoisomerase II checkpoint|intracellular signaling pathway involved in topo II checkpoint						jl	2013-02-28T16:07:26Z			GO:0070683|GO:1902403			biological_process											owl:Class	
GO:0047801	biolink:NamedThing	L-cysteine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.	got7fsn_ti	L-cysteine aminotransferase activity|cysteine transaminase activity|CGT|cysteine aminotransferase activity											RHEA:17441|MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN|EC:2.6.1.3|Reactome:R-HSA-9012597		molecular_function											owl:Class	
GO:0005714	biolink:NamedThing	early recombination nodule	An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I.	got7fsn_ti														cellular_component											owl:Class	
GO:0008939	biolink:NamedThing	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity	Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate.	got7fsn_ti	nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase activity|CobT|N(1)-alpha-phosphoribosyltransferase activity|N1-alpha-phosphoribosyltransferase activity|nicotinate-nucleotide:5,6-dimethylbenzimidazole phospho-D-ribosyltransferase activity|nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase activity|nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase activity|nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase activity											RHEA:11196|MetaCyc:DMBPPRIBOSYLTRANS-RXN|KEGG_REACTION:R04148|EC:2.4.2.21		molecular_function											owl:Class	
GO:0000762	biolink:NamedThing	pheromone-induced unidirectional conjugation	The process of unidirectional (polarized) transfer of genetic information in response to a pheromone. It involves direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types.	got7fsn_ti														biological_process											owl:Class	
GO:0071539	biolink:NamedThing	protein localization to centrosome	A process in which a protein is transported to, or maintained at, the centrosome.	got7fsn_ti	protein localisation to centrosome						mah	2010-01-12T02:09:45Z						biological_process											owl:Class	
GO:0072629	biolink:NamedThing	interleukin-28B production	The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL28B production|interleukin-28B secretion|interferon lambda 3 production|IL-28B production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072630			biological_process											owl:Class	
GO:0060732	biolink:NamedThing	positive regulation of inositol phosphate biosynthetic process	Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	got7fsn_ti							dph	2009-06-12T01:58:23Z						biological_process											owl:Class	
GO:1990650	biolink:NamedThing	inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate.	got7fsn_ti							al	2015-02-23T11:14:17Z						molecular_function											owl:Class	
GO:0000388	biolink:NamedThing	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).	got7fsn_ti	3'-splice site cleavage, exon ligation|U12-type spliceosome conformational change to release U4atac and U11|spliceosomal B2 complex formation|spliceosomal A1 complex biosynthesis|spliceosomal A1 complex formation|spliceosomal B2 complex biosynthesis|U2-type spliceosome conformational change to release U4 and U1				Note that this step represents formation of the A1 complex (yeast) or the B2 complex (mammalian).						GO:0000396|GO:0000397			biological_process											owl:Class	
GO:0060870	biolink:NamedThing	cell wall disassembly involved in floral organ abscission	A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission.	got7fsn_ti							dph	2009-08-12T07:15:36Z						biological_process											owl:Class	
GO:0047144	biolink:NamedThing	2-acylglycerol-3-phosphate O-acyltransferase activity	Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.	got7fsn_ti	acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase activity|2-acylglycerophosphate acyltransferase activity											Reactome:R-HSA-1482691|Reactome:R-HSA-1482533|Reactome:R-HSA-1482646|Reactome:R-HSA-1482546|MetaCyc:2-ACYL2.3.1.15-RXN|Reactome:R-HSA-1482626|Reactome:R-HSA-1482635|RHEA:14233|EC:2.3.1.52		molecular_function											owl:Class	
GO:0004359	biolink:NamedThing	glutaminase activity	Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.	got7fsn_ti	L-glutaminase activity|glutamine aminohydrolase activity|L-glutamine amidohydrolase activity|glutaminase I											RHEA:15889|Reactome:R-HSA-70609|MetaCyc:GLUTAMIN-RXN|EC:3.5.1.2		molecular_function											owl:Class	
GO:0071122	biolink:NamedThing	alpha9-beta1 integrin-VEGF-A complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.	got7fsn_ti	ITGA9-ITGB1-VEGFA complex						mah	2009-11-13T02:22:01Z						cellular_component											owl:Class	
GO:0003113	biolink:NamedThing	positive regulation of heart rate by neuronal norepinephrine	The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction.	got7fsn_ti	positive regulation of heart rate by neuronal noradrenaline													biological_process											owl:Class	
GO:0047450	biolink:NamedThing	crotonoyl-[acyl-carrier-protein] hydratase activity	Catalysis of the reaction: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = H2O + but-2-enoyl-[acyl-carrier protein].	got7fsn_ti	crotonoyl-[acyl-carrier protein] hydratase activity|(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase activity|(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase activity|3-hydroxybutyryl acyl carrier protein dehydratase activity|enoyl acyl carrier protein hydrase activity|(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase (but-2-enoyl-acyl-carrier protein-forming)|beta-hydroxybutyryl acyl carrier protein dehydrase activity|beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase activity|crotonoyl-acyl-carrier-protein hydratase activity|crotonyl acyl carrier protein hydratase activity|crotonoyl-ACP hydratase activity										GO:0080063	EC:4.2.1.58|KEGG_REACTION:R04428|MetaCyc:4.2.1.58-RXN		molecular_function											owl:Class	
GO:0007023	biolink:NamedThing	post-chaperonin tubulin folding pathway	Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors.	got7fsn_ti														biological_process											owl:Class	
GO:0090078	biolink:NamedThing	smooth muscle derived foam cell differentiation	The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	got7fsn_ti							tb	2009-09-15T03:48:10Z						biological_process											owl:Class	
GO:0102798	biolink:NamedThing	heptaldehyde:oxygen oxidoreductase activity	Catalysis of the reaction: heptanal + O2 + H2O = H+ + heptanoate + hydrogen peroxide.	got7fsn_ti												EC:1.2.3.1|MetaCyc:RXN-8094		molecular_function											owl:Class	
GO:0034722	biolink:NamedThing	gamma-glutamyl-peptidase activity	Catalysis of the cleavage of a gamma-linked glutamate bond.	got7fsn_ti	gamma-glutamyl hydrolase activity											EC:3.4.19.9|RHEA:56784|MetaCyc:3.4.19.9-RXN		molecular_function											owl:Class	
GO:1990280	biolink:NamedThing	RNA localization to chromatin	A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin.	got7fsn_ti	RNA localisation to chromatin						mah	2014-01-30T15:55:34Z						biological_process											owl:Class	
GO:1900116	biolink:NamedThing	extracellular negative regulation of signal transduction	Any negative regulation of signal transduction that takes place in extracellular region.	got7fsn_ti	inhibition of signal transduction in extracellular region|down-regulation of signal transduction in extracellular region|negative regulation of signalling pathway in extracellular region|negative regulation of signaling pathway in extracellular region|extracellular inhibition of signaling pathway|down regulation of signal transduction in extracellular region|downregulation of signal transduction in extracellular region						bf	2012-02-22T10:27:56Z						biological_process											owl:Class	
GO:0050398	biolink:NamedThing	wax-ester hydrolase activity	Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.	got7fsn_ti	wax-ester acylhydrolase activity|jojoba wax esterase|WEH											MetaCyc:WAX-ESTER-HYDROLASE-RXN|EC:3.1.1.50|RHEA:13577		molecular_function											owl:Class	
GO:0071796	biolink:NamedThing	K6-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein.	got7fsn_ti							mah	2010-09-02T02:13:07Z						molecular_function											owl:Class	
GO:1990323	biolink:NamedThing	collagen type XXIV trimer	A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development.	got7fsn_ti							bhm	2014-03-14T22:05:53Z						cellular_component											owl:Class	
GO:0052901	biolink:NamedThing	spermine:oxygen oxidoreductase (spermidine-forming) activity	Catalysis of the reaction: H(2)O + O(2) + spermine = 3-aminopropanal + H(2)O(2) + spermidine.	got7fsn_ti	spermine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity|N(1)-acetylpolyamine oxidase activity											EC:1.5.3.17|RHEA:25804|Reactome:R-HSA-141341|MetaCyc:RXN-9015|MetaCyc:1.5.3.17-RXN|EC:1.5.3.13|KEGG_REACTION:R09076|EC:1.5.3.16		molecular_function											owl:Class	
GO:0010609	biolink:NamedThing	mRNA localization resulting in posttranscriptional regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell.	got7fsn_ti	posttranscriptional regulation of gene expression by mRNA localisation|mRNA localisation resulting in posttranscriptional regulation of gene expression|posttranscriptional regulation of gene expression by mRNA localization													biological_process											owl:Class	
GO:0019773	biolink:NamedThing	proteasome core complex, alpha-subunit complex	The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.	got7fsn_ti														cellular_component											owl:Class	
GO:0098594	biolink:NamedThing	mucin granule	A secretory granule that contains mucin.	got7fsn_ti							dos	2014-03-11T15:59:11Z						cellular_component											owl:Class	
GO:1990798	biolink:NamedThing	pancreas regeneration	The regrowth of a destroyed pancreas.	got7fsn_ti							sl	2015-07-10T22:53:53Z						biological_process											owl:Class	
GO:1990764	biolink:NamedThing	myofibroblast contraction	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast.	got7fsn_ti	MF contraction|MFB contraction						sl	2015-06-09T23:43:09Z						biological_process											owl:Class	
GO:0102634	biolink:NamedThing	1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity	Catalysis of the reaction: naphthalene-1,3,6,8-tetrol + O2 <=> flaviolin-2-olate + H2O + H+.	got7fsn_ti												MetaCyc:RXN-15586		molecular_function											owl:Class	
GO:0034937	biolink:NamedThing	perchlorate reductase activity	Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O.	got7fsn_ti												EC:1.97.1.-|UM-BBD_reactionID:r0980		molecular_function											owl:Class	
GO:0008987	biolink:NamedThing	quinolinate synthetase A activity	Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.	got7fsn_ti												MetaCyc:QUINOLINATE-SYNTHA-RXN|RHEA:25888		molecular_function											owl:Class	
GO:0035938	biolink:NamedThing	estradiol secretion	The regulated release of estradiol into the circulatory system.	got7fsn_ti	oestradiol secretion						bf	2011-07-20T01:16:45Z						biological_process											owl:Class	
GO:0004980	biolink:NamedThing	melanocyte-stimulating hormone receptor activity	Combining with melanocyte-stimulating hormone to initiate a change in cell activity.	got7fsn_ti	melanophore-stimulating hormone receptor activity|MSH receptor activity|MSHR activity|melanocyte stimulating hormone receptor activity													molecular_function											owl:Class	
GO:0072547	biolink:NamedThing	tricoumaroylspermidine meta-hydroxylase activity	Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O.	got7fsn_ti	tricoumaroyl spermidine meta-hydroxylase activity						mah	2011-01-25T02:49:37Z				MetaCyc:RXN-11260		molecular_function											owl:Class	
GO:0080005	biolink:NamedThing	photosystem stoichiometry adjustment	Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0010109	biolink:NamedThing	regulation of photosynthesis	Any process that modulates the frequency, rate or extent of photosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0036077	biolink:NamedThing	intratendonous ossification	Ossification wherein bone tissue forms within tendonous tissue.	got7fsn_ti					Tendonous ossification may occur via replacement ossification or metaplastic ossification or both in any one instance.		bf	2011-12-19T01:57:48Z						biological_process											owl:Class	
GO:0014035	biolink:NamedThing	neural crest cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0055042	biolink:NamedThing	5-valerolactone hydrolase activity	Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate.	got7fsn_ti														molecular_function											owl:Class	
GO:0034547	biolink:NamedThing	N-cyclopropylmelamine deaminase activity	Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3.	got7fsn_ti												UM-BBD_reactionID:r0825|MetaCyc:RXN-8018		molecular_function											owl:Class	
GO:0042747	biolink:NamedThing	circadian sleep/wake cycle, REM sleep	A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.	got7fsn_ti														biological_process											owl:Class	
GO:0098763	biolink:NamedThing	mitotic cell cycle phase	One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.	got7fsn_ti					This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0010055	biolink:NamedThing	atrichoblast differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair.	got7fsn_ti														biological_process											owl:Class	
GO:0097353	biolink:NamedThing	centrolateral pattern formation	The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment.	got7fsn_ti	mediolateral pattern formation						pr	2012-07-02T11:34:08Z						biological_process											owl:Class	
GO:0103035	biolink:NamedThing	NAD(P)H:methyl-1,4-benzoquinone oxidoreductase activity	Catalysis of the reaction: 3 H+ + methyl-1,4-benzoquinone + NADPH = methyl-1,4-benzoquinol + NADP.	got7fsn_ti												MetaCyc:RXN0-5387		molecular_function											owl:Class	
GO:0004065	biolink:NamedThing	arylsulfatase activity	Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.	got7fsn_ti	sulfatase activity|estrogen sulfatase activity|p-nitrophenyl sulfatase activity|phenolsulfatase activity|phenylsulfatase activity|aryl-sulfate sulfohydrolase activity|aryl-sulfate sulphohydrolase activity|arylsulphatase activity|nitrocatechol sulfatase activity|aryl-sulphate sulphohydrolase activity|4-methylumbelliferyl sulfatase activity|arylsulfohydrolase activity											MetaCyc:ARYLSULFAT-RXN|EC:3.1.6.1|RHEA:17261		molecular_function											owl:Class	
GO:0046723	biolink:NamedThing	malic acid secretion	The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue.	got7fsn_ti	hydroxysuccinic acid secretion|malate secretion													biological_process											owl:Class	
GO:0071969	biolink:NamedThing	fungal-type cell wall (1->3)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi.	got7fsn_ti	fungal-type cell wall 1,3-beta-glucan metabolism|fungal-type cell wall beta-1,3 glucan metabolism|fungal-type cell wall beta-1,3 glucan metabolic process|fungal-type cell wall 1,3-beta-D-glucan metabolic process						mah	2010-10-18T03:25:38Z						biological_process											owl:Class	
GO:0097022	biolink:NamedThing	lymphocyte migration into lymph node	The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.	got7fsn_ti	lymphocyte homing						pr	2011-03-29T04:29:27Z						biological_process											owl:Class	
GO:0042397	biolink:NamedThing	phosphagen catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.	got7fsn_ti	phosphagen breakdown|phosphagen catabolism|phosphagen degradation													biological_process											owl:Class	
GO:0102256	biolink:NamedThing	neoagarohexaose 1,3-alpha-3,6-anhydro-L-galactosidase activity	Catalysis of the reaction: neoagarohexaose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agaropentaose.	got7fsn_ti												MetaCyc:RXN-12429|EC:3.2.1.159		molecular_function											owl:Class	
GO:0036511	biolink:NamedThing	trimming of first mannose on A branch	The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.	got7fsn_ti	glycoprotein mannose trimming on A branch|conversion of M9 to M8A|conversion of (Man)9(GlcNAc)2 to (Man)8A(GlcNAc)2				Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T14:14:03Z						biological_process											owl:Class	
GO:0120320	biolink:NamedThing	lateral pseudopodium retraction	The myosin-based contraction and retraction of a lateral pseudopodium.	got7fsn_ti	lateral pseudopodium suppression						krc	2021-06-23T21:50:09Z						biological_process											owl:Class	
GO:0031270	biolink:NamedThing	pseudopodium retraction	The myosin-based contraction and retraction of a pseudopodium.	got7fsn_ti														biological_process											owl:Class	
GO:0009643	biolink:NamedThing	photosynthetic acclimation	A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light.	got7fsn_ti	photoacclimation|light acclimatization													biological_process											owl:Class	
GO:0044197	biolink:NamedThing	Rel homology domain binding	Binding to a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT.	got7fsn_ti	RHD binding						jl	2009-10-20T03:57:48Z						molecular_function											owl:Class	
GO:0120036	biolink:NamedThing	plasma membrane bounded cell projection organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13298					krc	2017-04-26T16:07:02Z						biological_process											owl:Class	
GO:0002396	biolink:NamedThing	MHC protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0006021	biolink:NamedThing	inositol biosynthetic process	The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.	got7fsn_ti	vitamin Bh biosynthesis|inositol formation|myo-inositol biosynthesis|inositol biosynthesis|inositol synthesis|vitamin Bh biosynthetic process|inositol anabolism|myo-inositol biosynthetic process													biological_process											owl:Class	
GO:0090648	biolink:NamedThing	response to environmental enrichment	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment.	got7fsn_ti	response to the introduction of novel objects						tb	2015-07-01T10:20:37Z						biological_process											owl:Class	
GO:0071093	biolink:NamedThing	alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.	got7fsn_ti	ITGA5-ITGB1-FN1-TGM2 complex						mah	2009-11-06T04:47:22Z						cellular_component											owl:Class	
GO:0071188	biolink:NamedThing	protocadherin-alpha-v7-protocadherin-gamma-a1 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti	Pcdha7-Pcdhga1 complex						mah	2009-11-23T04:23:25Z						cellular_component											owl:Class	
GO:2001107	biolink:NamedThing	negative regulation of Rho guanyl-nucleotide exchange factor activity	Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.	got7fsn_ti	negative regulation of Rho guanine nucleotide exchange factor|negative regulation of RhoGEF						yaf	2011-09-23T10:13:12Z						biological_process											owl:Class	
GO:1905098	biolink:NamedThing	negative regulation of guanyl-nucleotide exchange factor activity	Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.	got7fsn_ti	downregulation of guanyl-nucleotide release factor activity|downregulation of guanyl-nucleotide exchange factor activity|down regulation of guanyl-nucleotide exchange factor activity|downregulation of guanyl-nucleotide releasing factor|inhibition of guanyl-nucleotide releasing factor|down regulation of GEF|negative regulation of guanyl-nucleotide releasing factor|inhibition of GDS|down-regulation of GNRP|down regulation of guanyl-nucleotide releasing factor|inhibition of GEF|downregulation of GDP-dissociation stimulator activity|inhibition of GDP-dissociation stimulator activity|downregulation of GEF|negative regulation of GDS|down regulation of GNRP|down regulation of GDP-dissociation stimulator activity|inhibition of guanyl-nucleotide release factor activity|negative regulation of GEF|down regulation of GDS|downregulation of GDS|down-regulation of GDS|negative regulation of guanyl-nucleotide release factor activity|negative regulation of GDP-dissociation stimulator activity|down-regulation of GDP-dissociation stimulator activity|downregulation of GNRP|negative regulation of GNRP|inhibition of GNRP|inhibition of guanyl-nucleotide exchange factor activity|down-regulation of guanyl-nucleotide exchange factor activity|down-regulation of guanyl-nucleotide releasing factor|down-regulation of guanyl-nucleotide release factor activity|down regulation of guanyl-nucleotide release factor activity|down-regulation of GEF	https://github.com/geneontology/go-ontology/issues/18750					sl	2016-03-31T16:09:45Z						biological_process											owl:Class	
GO:0016498	biolink:NamedThing	neuromedin K receptor activity	Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity.	got7fsn_ti	neurokinin B receptor activity													molecular_function											owl:Class	
GO:0060653	biolink:NamedThing	epithelial cell differentiation involved in mammary gland cord morphogenesis	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.	got7fsn_ti	epithelial cell differentiation involved in mammary gland sprout morphogenesis						dph	2009-05-29T09:17:16Z						biological_process											owl:Class	
GO:0061435	biolink:NamedThing	positive regulation of transcription from a mobile element promoter	Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.	got7fsn_ti							dph	2012-02-09T10:01:33Z						biological_process											owl:Class	
GO:0061531	biolink:NamedThing	primary amine secretion	The regulated release of a primary amine by a cell.	got7fsn_ti							dph	2013-06-21T15:56:08Z						biological_process											owl:Class	
GO:1903775	biolink:NamedThing	regulation of DNA double-strand break processing	Any process that modulates the frequency, rate or extent of DNA double-strand break processing.	got7fsn_ti							al	2015-01-06T17:08:15Z						biological_process											owl:Class	
GO:0034003	biolink:NamedThing	vetispiradiene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene.	got7fsn_ti	trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming) activity|vetispiradiene-forming farnesyl pyrophosphate cyclase activity|pemnaspirodiene synthase activity|HVS|vetispiradiene cyclase activity											KEGG_REACTION:R06523|EC:4.2.3.21|MetaCyc:RXN-4823|RHEA:10340		molecular_function											owl:Class	
GO:0019389	biolink:NamedThing	glucuronoside metabolic process	The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.	got7fsn_ti	glucuronoside metabolism|glucuronide metabolism|glucuronide metabolic process													biological_process											owl:Class	
GO:0007196	biolink:NamedThing	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	got7fsn_ti	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|inhibition of adenylate cyclase activity by G-protein-coupled glutamate receptor signaling pathway|inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway|metabotropic glutamate receptor, adenylyl cyclase inhibiting pathway|metabotropic glutamate receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by metabotropic glutamate receptor signalling pathway													biological_process											owl:Class	
GO:0102972	biolink:NamedThing	gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming)	Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 = gibberellin A110 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-947		molecular_function											owl:Class	
GO:0042198	biolink:NamedThing	nylon metabolic process	The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.	got7fsn_ti	nylon metabolism													biological_process											owl:Class	
GO:0047953	biolink:NamedThing	glycerol 2-dehydrogenase (NADP+) activity	Catalysis of the reaction: glycerol + NADP(+) = glycerone + H(+) + NADPH.	got7fsn_ti	glycerol:NADP+ 2-oxidoreductase (glycerone-forming)|dihydroxyacetone reductase activity|dihydroxyacetone (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|DHA oxidoreductase activity|dihydroxyacetone reductase (NADPH)											MetaCyc:GLYCEROL-2-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.156|RHEA:12753|KEGG_REACTION:R01039		molecular_function											owl:Class	
GO:0043760	biolink:NamedThing	acetyldiaminopimelate aminotransferase activity	Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate.	got7fsn_ti	N-acetyl-L,L-diaminopimelate aminotransferase activity|N-acetyl-diaminopimelate aminotransferase activity													molecular_function											owl:Class	
GO:0031723	biolink:NamedThing	CXCR4 chemokine receptor binding	Binding to a CXCR4 chemokine receptor.	got7fsn_ti	CXCR4 chemokine receptor ligand|stromal cell-derived factor 1 receptor binding													molecular_function											owl:Class	
GO:0001155	biolink:NamedThing	TFIIIA-class transcription factor binding	Binding to an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at RNA polymerase III promoters.	got7fsn_ti							krc	2011-01-27T04:57:49Z						molecular_function											owl:Class	
GO:0046028	biolink:NamedThing	electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity	Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II.	got7fsn_ti	plastocyanin													molecular_function											owl:Class	
GO:0006868	biolink:NamedThing	glutamine transport	The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-glutamine transport										GO:0015815			biological_process											owl:Class	
GO:0033729	biolink:NamedThing	anthocyanidin reductase activity	Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+.	got7fsn_ti	MtANR|flavan-3-ol:NAD(P)+ oxidoreductase activity|ANR|AtANR											MetaCyc:1.3.1.77-RXN|EC:1.3.1.77		molecular_function											owl:Class	
GO:0048930	biolink:NamedThing	glial cell migration in posterior lateral line nerve	The movement of a glial cell along the axons in the posterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0007395	biolink:NamedThing	dorsal closure, spreading of leading edge cells	Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa.	got7fsn_ti														biological_process											owl:Class	
GO:0031499	biolink:NamedThing	TRAMP complex	A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.	got7fsn_ti	Trf4 poly(A) polymerase complex|TRAMP4 complex|TRAMP5 complex|Trf4p-Air2p-Mtr4p polyadenylation complex|Trf4 complex											Wikipedia:TRAMP_complex		cellular_component											owl:Class	
GO:0034288	biolink:NamedThing	detection of disaccharide stimulus	The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal.	got7fsn_ti	perception of disaccharide stimulus													biological_process											owl:Class	
GO:0050554	biolink:NamedThing	abietadiene synthase activity	Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.	got7fsn_ti	abietadiene cyclase activity|copalyl-diphosphate diphosphate-lyase (cyclizing)|(+)-copalyl-diphosphate diphosphate-lyase (cyclizing, (-)-abietadiene-forming)											MetaCyc:4.2.3.18-RXN|EC:4.2.3.18|RHEA:13873|KEGG_REACTION:R06301		molecular_function											owl:Class	
GO:0000453	biolink:NamedThing	enzyme-directed rRNA 2'-O-methylation	The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA.	got7fsn_ti														biological_process											owl:Class	
GO:0103007	biolink:NamedThing	indole-3-acetate carboxyl methyltransferase activity	Catalysis of the reaction: indole-3-acetate + S-adenosyl-L-methionine  <=> methyl (indol-3-yl)acetate + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.278|RHEA:36131|MetaCyc:RXN-9825		molecular_function											owl:Class	
GO:0034407	biolink:NamedThing	cell wall (1->3)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.	got7fsn_ti	cell wall beta-1,3 glucan metabolic process|cell wall 1,3-beta-glucan metabolism|cell wall 1,3-beta-D-glucan metabolic process|cell wall 1,3-beta-glucan metabolic process|cell wall beta-1,3 glucan metabolism													biological_process											owl:Class	
GO:0006074	biolink:NamedThing	(1->3)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.	got7fsn_ti	beta-1,3 glucan metabolic process|1,3-beta-glucan metabolic process|1,3-beta-D-glucan metabolism|1,3-beta-D-glucan metabolic process|beta-1,3 glucan metabolism													biological_process											owl:Class	
GO:0050421	biolink:NamedThing	nitrite reductase (NO-forming) activity	Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+.	got7fsn_ti	methyl viologen-nitrite reductase activity|nitrite reductase (cytochrome; NO-forming) activity|cytochrome cd1 activity|NO-forming nitrite reductase (cytochrome) activity|cytochrome cd activity|Pseudomonas cytochrome oxidase activity|cd-cytochrome nitrite reductase activity|cytochrome c-551:O2, NO2+ oxidoreductase activity|NO-forming nitrite reductase activity|[nitrite reductase (cytochrome)]|cytochrome c-551:O(2), NO(2)(+) oxidoreductase activity|nitric-oxide:ferricytochrome-c oxidoreductase activity				Note that EC:1.7.99.3 was merged into this term.						GO:0016666	RHEA:15233|MetaCyc:NITRITE-REDUCTASE-CYTOCHROME-RXN|EC:1.7.2.1		molecular_function											owl:Class	
GO:0098676	biolink:NamedThing	modulation of host virulence by virus	Any process by which a virus modulates the ability of its host to infect and/or damage an organism for which it is a host.  Typically this involves a phage modulating the virulence of a bacterium.  Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production exotoxins or provide protection against host immune defenses.	got7fsn_ti							dos	2017-01-19T11:59:46Z				VZ:3965		biological_process											owl:Class	
GO:0102796	biolink:NamedThing	protocatechualdehyde:oxygen oxidoreductase activity	Catalysis of the reaction: 3,4-dihydroxybenzaldehyde + O2 + H2O <=> H+ + 3,4-dihydroxybenzoate + hydrogen peroxide.	got7fsn_ti												MetaCyc:RXN-8091|EC:1.2.3.9		molecular_function											owl:Class	
GO:0033439	biolink:NamedThing	ACA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an ACA codon.	got7fsn_ti	threonine tRNA				Note that in the standard genetic code, ACA codes for threonine.									molecular_function											owl:Class	
GO:0003921	biolink:NamedThing	GMP synthase activity	Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+).	got7fsn_ti												RHEA:18301|MetaCyc:GMP-SYN-NH3-RXN		molecular_function											owl:Class	
GO:0044466	biolink:NamedThing	glutaryl-CoA hydrolase activity	Catalysis of the reaction: glutaryl-CoA + H2O = CoA + glutarate.	got7fsn_ti	glutaryl-CoA thioesterase activity						jl	2012-01-17T04:16:43Z				EC:3.1.2.3		molecular_function											owl:Class	
GO:0004424	biolink:NamedThing	imidazoleglycerol-phosphate dehydratase activity	Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O.	got7fsn_ti	IGP dehydratase activity|imidazoleglycerol phosphate dehydratase activity|D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase activity|D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase [3-(imidazol-4-yl)-2-oxopropyl-phosphate-forming]											EC:4.2.1.19|KEGG_REACTION:R03457|RHEA:11040|MetaCyc:IMIDPHOSDEHYD-RXN		molecular_function											owl:Class	
GO:0047916	biolink:NamedThing	GDP-6-deoxy-D-talose 4-dehydrogenase activity	Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+.	got7fsn_ti	guanosine diphospho-6-deoxy-D-talose dehydrogenase activity|GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase activity											EC:1.1.1.135|MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0051944	biolink:NamedThing	positive regulation of catecholamine uptake involved in synaptic transmission	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.	got7fsn_ti	positive regulation of catecholamine neurotransmitter reuptake|up-regulation of catecholamine uptake during transmission of nerve impulse|upregulation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine neurotransmitter uptake|activation of catecholamine uptake during transmission of nerve impulse|up regulation of catecholamine uptake during transmission of nerve impulse|stimulation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0047651	biolink:NamedThing	alkylhalidase activity	Catalysis of the reaction: bromochloromethane + H(2)O = bromide + chloride + formaldehyde + 2 H(+).	got7fsn_ti	alkyl-halide halidohydrolase activity|halogenase activity|haloalkane halidohydrolase activity											MetaCyc:ALKYLHALIDASE-RXN|RHEA:13765|KEGG_REACTION:R03523		molecular_function											owl:Class	
GO:0002145	biolink:NamedThing	4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity	Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H(+).	got7fsn_ti	HMP-PP diphosphatase|HMP-PP pyrophosphatase						hjd	2009-06-10T11:21:35Z				MetaCyc:RXN0-3543|RHEA:27914		molecular_function											owl:Class	
GO:0071000	biolink:NamedThing	response to magnetism	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.	got7fsn_ti	response to magnetic stimulus						mah	2009-11-04T12:02:03Z						biological_process											owl:Class	
GO:0070506	biolink:NamedThing	high-density lipoprotein particle receptor activity	Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.	got7fsn_ti	high-density lipoprotein receptor activity|HDL receptor													molecular_function											owl:Class	
GO:0047070	biolink:NamedThing	3-carboxyethylcatechol 2,3-dioxygenase activity	Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.	got7fsn_ti	3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing)|3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase activity|2,3-dihydroxy-beta-phenylpropionic dioxygenase activity|2,3-dihydroxy-beta-phenylpropionate oxygenase activity										GO:0008669	MetaCyc:1.13.11.16-RXN|RHEA:23840|EC:1.13.11.16		molecular_function											owl:Class	
GO:0047956	biolink:NamedThing	glycerol dehydrogenase [NADP+] activity	Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.	got7fsn_ti	glycerol:NADP+ oxidoreductase activity|glycerol dehydrogenase (NADP+) activity											MetaCyc:GLYCEROL-DEHYDROGENASE-NADP+-RXN|RHEA:23592|EC:1.1.1.72		molecular_function											owl:Class	
GO:0051907	biolink:NamedThing	S-(hydroxymethyl)glutathione synthase activity	Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione.	got7fsn_ti	glutathione-dependent formaldehyde-activating enzyme activity|S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)|S-(hydroxymethyl)glutathione formaldehyde-lyase activity|Gfa											UM-BBD_reactionID:r1145|MetaCyc:RXN-2961|EC:4.4.1.22|RHEA:22488|KEGG_REACTION:R06982		molecular_function											owl:Class	
GO:0035702	biolink:NamedThing	monocyte homeostasis	The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.	got7fsn_ti							bf	2011-03-02T11:32:57Z						biological_process											owl:Class	
GO:0050080	biolink:NamedThing	malonyl-CoA decarboxylase activity	Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2.	got7fsn_ti	malonyl-CoA carboxy-lyase (acetyl-CoA-forming)|malonyl coenzyme A decarboxylase activity|malonyl-CoA carboxy-lyase activity											MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN|EC:4.1.1.9|Reactome:R-HSA-977317|RHEA:18781		molecular_function											owl:Class	
GO:0002498	biolink:NamedThing	proteolysis within endoplasmic reticulum associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.	got7fsn_ti	proteolysis within ER associated with antigen processing and presentation|endoplasmic reticulum proteolysis associated with antigen processing and presentation|ER proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0048334	biolink:NamedThing	regulation of mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of mesoderm cell fate determination.	got7fsn_ti														biological_process											owl:Class	
GO:0102337	biolink:NamedThing	3-oxo-cerotoyl-CoA synthase activity	Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + carbon dioxide + coenzyme A.	got7fsn_ti												MetaCyc:RXN-13296|RHEA:36515		molecular_function											owl:Class	
GO:0035540	biolink:NamedThing	positive regulation of SNARE complex disassembly	Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	got7fsn_ti							bf	2010-05-10T01:42:21Z						biological_process											owl:Class	
GO:0090483	biolink:NamedThing	phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity	Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine.	got7fsn_ti	cardiolipin synthase						tb	2012-10-03T14:20:05Z						molecular_function											owl:Class	
GO:0019141	biolink:NamedThing	2-dehydropantolactone reductase (B-specific) activity	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.	got7fsn_ti	2-ketopantoyl lactone reductase activity|(R)-pantolactone:NADP+ oxidoreductase (B-specific)|2-oxopantoyl lactone reductase|2-dehydropantoyl-lactone reductase (B-specific) activity|ketopantoyl lactone reductase activity											EC:1.1.1.214|MetaCyc:DEHYDROPANTLACRED-RXN		molecular_function											owl:Class	
GO:0016728	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group.	got7fsn_ti	oxidoreductase activity, acting on CH or CH2 groups, disulphide as acceptor											EC:1.17.4.-		molecular_function											owl:Class	
GO:0036099	biolink:NamedThing	female germ-line stem cell population maintenance	The process by which an organism or tissue maintains a population of female germ-line stem cells.	got7fsn_ti							bf	2012-01-26T01:58:10Z						biological_process											owl:Class	
GO:0008496	biolink:NamedThing	mannan endo-1,6-alpha-mannosidase activity	Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans.	got7fsn_ti	exo-1,6-beta-mannanase activity|endo-alpha-D-mannosidase activity|1,6-alpha-D-mannan mannanohydrolase activity|endo-alpha-1->6-D-mannanase activity|endo-1,6-beta-mannanase activity|1,6-beta-D-mannan mannanohydrolase activity|mannan endo-1,6-beta-mannosidase activity											MetaCyc:3.2.1.101-RXN|Reactome:R-HSA-6799581|EC:3.2.1.101		molecular_function											owl:Class	
GO:0047865	biolink:NamedThing	dimethylglycine dehydrogenase activity	Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein.	got7fsn_ti	N,N-dimethylglycine oxidase activity|N,N-dimethylglycine:acceptor oxidoreductase (demethylating)|N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating)				Note that this was EC:1.5.99.2.							Reactome:R-HSA-6797653|EC:1.5.8.4|MetaCyc:DIMETHYLGLYCINE-DEHYDROGENASE-RXN|RHEA:52856|KEGG_REACTION:R01565		molecular_function											owl:Class	
GO:0010215	biolink:NamedThing	cellulose microfibril organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall.	got7fsn_ti	cellulose microfibril organisation													biological_process											owl:Class	
GO:0070551	biolink:NamedThing	endoribonuclease activity, cleaving siRNA-paired mRNA	Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.	got7fsn_ti	argonaute endoribonuclease activity													molecular_function											owl:Class	
GO:0046485	biolink:NamedThing	ether lipid metabolic process	The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.	got7fsn_ti	plasmalogen metabolic process|ether lipid metabolism											Wikipedia:Ether_lipid		biological_process											owl:Class	
GO:0103111	biolink:NamedThing	D-glucosamine PTS permease activity	Catalysis of the reaction: a [PTS enzyme I]-Npi-phospho-L-histidine + D-glucosamine <=> D-glucosamine 6-phosphate + a [PTS enzyme I]-L-histidine.	got7fsn_ti												MetaCyc:TRANS-RXN-167A|EC:2.7.1.69|RHEA:37359		molecular_function											owl:Class	
GO:0060486	biolink:NamedThing	club cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.	got7fsn_ti	Clara cell differentiation													biological_process											owl:Class	
GO:0004478	biolink:NamedThing	methionine adenosyltransferase activity	Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.	got7fsn_ti	S-adenosylmethionine synthase activity|adenosylmethionine synthetase activity|S-adenosyl-L-methionine synthetase activity|S-adenosylmethionine synthetase activity|methionine S-adenosyltransferase activity|ATP:L-methionine S-adenosyltransferase activity|ATP-methionine adenosyltransferase activity|methionine-activating enzyme|AdoMet synthetase activity											RHEA:21080|Reactome:R-HSA-5603087|Reactome:R-HSA-174391|EC:2.5.1.6|Reactome:R-HSA-5603114|MetaCyc:S-ADENMETSYN-RXN		molecular_function											owl:Class	
GO:0051735	biolink:NamedThing	GTP-dependent polynucleotide kinase activity	Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.	got7fsn_ti	GTP:5'-dephosphopolynucleotide 5'-phosphotransferase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity													molecular_function											owl:Class	
GO:0009057	biolink:NamedThing	macromolecule catabolic process	The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	got7fsn_ti	macromolecule degradation|macromolecule catabolism|biopolymer catabolic process|multicellular organismal macromolecule catabolic process|macromolecule breakdown										GO:0044266|GO:0043285			biological_process											owl:Class	
GO:0051633	biolink:NamedThing	positive regulation of acetylcholine uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.	got7fsn_ti	up-regulation of acetylcholine uptake|positive regulation of acetylcholine import|activation of acetylcholine uptake|up regulation of acetylcholine uptake|stimulation of acetylcholine uptake|upregulation of acetylcholine uptake													biological_process											owl:Class	
GO:0004819	biolink:NamedThing	glutamine-tRNA ligase activity	Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).	got7fsn_ti	GlnRS|glutaminyl-transfer ribonucleate synthetase activity|glutaminyl ribonucleic acid|glutaminyl-transfer RNA synthetase activity|L-glutamine:tRNAGln ligase (AMP-forming)|glutaminyl-tRNA synthetase activity|glutamine translase activity|glutamine-tRNA synthetase activity											MetaCyc:GLUTAMINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379982|Reactome:R-HSA-380241|EC:6.1.1.18|RHEA:20121		molecular_function											owl:Class	
GO:0102355	biolink:NamedThing	2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity	Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> 3-maleylpyruvate + H+.	got7fsn_ti												EC:3.1.1.91|RHEA:33967|MetaCyc:RXN-13371		molecular_function											owl:Class	
GO:0008261	biolink:NamedThing	allatostatin receptor activity	Combining with allatostatin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0019178	biolink:NamedThing	NADP phosphatase activity	Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate.	got7fsn_ti												MetaCyc:NADPPHOSPHAT-RXN		molecular_function											owl:Class	
GO:0032053	biolink:NamedThing	ciliary basal body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).	got7fsn_ti	microtubule basal body organisation|microtubule basal body organization|microtubule basal body organization and biogenesis													biological_process											owl:Class	
GO:0034956	biolink:NamedThing	diphenyl ether 1,2-dioxygenase activity	Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+.	got7fsn_ti												UM-BBD_reactionID:r1453|EC:1.13.11.-		molecular_function											owl:Class	
GO:0102822	biolink:NamedThing	quercetin 3'-O-methyltransferase activity	Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine  = H+ + isorhamnetin + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:55332|EC:2.1.1.42|MetaCyc:RXN-8262		molecular_function											owl:Class	
GO:0048007	biolink:NamedThing	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.	got7fsn_ti	exogenous lipid antigen processing and presentation via MHC class Ib|antigen presentation, exogenous peptide antigen													biological_process											owl:Class	
GO:0031259	biolink:NamedThing	uropod membrane	The portion of the plasma membrane surrounding a uropod.	got7fsn_ti	uropodium membrane													cellular_component											owl:Class	
GO:0019280	biolink:NamedThing	L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine	The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine.	got7fsn_ti	L-methionine synthesis from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine formation from homoserine via O-acetyl-L-homoserine and cystathionine|methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine											MetaCyc:HSERMETANA-PWY		biological_process											owl:Class	
GO:0019279	biolink:NamedThing	L-methionine biosynthetic process from L-homoserine via cystathionine	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine.	got7fsn_ti	L-methionine synthesis from L-homoserine via cystathionine|L-methionine formation from L-homoserine via cystathionine|methionine biosynthetic process from L-homoserine via cystathionine|L-methionine anabolism from L-homoserine via cystathionine											MetaCyc:HOMOSER-METSYN-PWY		biological_process											owl:Class	
GO:0051679	biolink:NamedThing	6-alpha-maltosylglucose metabolic process	The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose.	got7fsn_ti	isopanose metabolic process|6-alpha-maltosylglucose metabolism|isopanose metabolism													biological_process											owl:Class	
GO:0098977	biolink:NamedThing	inhibitory chemical synaptic transmission	Synaptic transmission that results in an inhibitory postsynaptic potential.	got7fsn_ti														biological_process											owl:Class	
GO:0003058	biolink:NamedThing	hormonal regulation of the force of heart contraction	The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.	got7fsn_ti	hormonal cardiac inotropy|hormonal regulation of the force of heart muscle contraction													biological_process											owl:Class	
GO:0035990	biolink:NamedThing	tendon cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.	got7fsn_ti	muscle attachment cell differentiation|tenocyte differentiation						bf	2011-08-26T04:16:06Z						biological_process											owl:Class	
GO:0106291	biolink:NamedThing	superoxide-generating NADH oxidase activity.	Catalysis of the reaction: NADH + 2 O2 = H(+) + NAD(+) + 2 superoxide.	got7fsn_ti							hjd	2020-08-19T15:56:43Z				RHEA:63184		molecular_function											owl:Class	
GO:0047510	biolink:NamedThing	(S)-2-methylmalate dehydratase activity	Catalysis of the reaction: S-citramalate = H(2)O + mesaconate.	got7fsn_ti	mesaconate mesaconase activity|mesaconate hydratase activity|mesaconase activity|L-citramalate hydrolase activity|(S)-2-methylmalate hydro-lyase activity|citramalate dehydratase activity|(+)-citramalic hydro-lyase activity|(+)-citramalate hydro-lyase activity|(S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)											EC:4.2.1.34|KEGG_REACTION:R03693|RHEA:13529|MetaCyc:S-2-METHYLMALATE-DEHYDRATASE-RXN		molecular_function											owl:Class	
GO:0050812	biolink:NamedThing	regulation of acyl-CoA biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA.	got7fsn_ti	regulation of acyl-CoA formation|regulation of acyl-CoA synthesis|regulation of acyl-CoA anabolism|regulation of acyl-CoA biosynthesis													biological_process											owl:Class	
GO:0102251	biolink:NamedThing	all-trans-beta-apo-10'-carotenal cleavage oxygenase activity	Catalysis of the reaction: 10'-apo-beta-carotenal + O2 <=> 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial.	got7fsn_ti												MetaCyc:RXN-12393|EC:1.13.11.70|RHEA:26401		molecular_function											owl:Class	
GO:0047892	biolink:NamedThing	flavone apiosyltransferase activity	Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.	got7fsn_ti	uridine diphosphoapiose-flavone apiosyltransferase activity|UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase activity|UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase activity											MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN|RHEA:19153|EC:2.4.2.25		molecular_function											owl:Class	
GO:0033251	biolink:NamedThing	cephalosporinase activity	Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin.	got7fsn_ti												MetaCyc:BETA-LACTAMASE-RXN		molecular_function											owl:Class	
GO:0033652	biolink:NamedThing	host cell chloroplast	A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														cellular_component											owl:Class	
GO:0047216	biolink:NamedThing	inositol 3-alpha-galactosyltransferase activity	Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP.	got7fsn_ti	UDP-D-galactose:inositol galactosyltransferase activity|galactinol synthase activity|UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase activity|uridine diphosphogalactose-inositol galactosyltransferase activity|UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase activity|inositol 1-alpha-galactosyltransferase activity|UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase activity											MetaCyc:2.4.1.123-RXN|RHEA:12464|EC:2.4.1.123		molecular_function											owl:Class	
GO:0102116	biolink:NamedThing	laurate hydroxylase activity	Catalysis of the reaction: dodecanoate + NADPH + O2 + H+ <=> 11-hydroxylaurate + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-11340		molecular_function											owl:Class	
GO:0102646	biolink:NamedThing	14betaH-scalarane-17alpha-19-diol synthase activity	Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O.	got7fsn_ti												MetaCyc:RXN-15759		molecular_function											owl:Class	
GO:0150059	biolink:NamedThing	amylin receptor 1 signaling pathway	A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).	got7fsn_ti	AMY1 signaling pathway						bc	2018-06-21T10:58:02Z						biological_process											owl:Class	
GO:0022832	biolink:NamedThing	voltage-gated channel activity	Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti														molecular_function											owl:Class	
GO:0035000	biolink:NamedThing	oligosaccharyltransferase III complex	An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes.	got7fsn_ti	OSTCIII													cellular_component											owl:Class	
GO:0043636	biolink:NamedThing	bisphenol A catabolic process	The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins.	got7fsn_ti	bisphenol-A catabolic process|bisphenol-A catabolism													biological_process											owl:Class	
GO:0047735	biolink:NamedThing	cellobiose dehydrogenase (acceptor) activity	Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.	got7fsn_ti	cellobiose:oxygen 1-oxidoreductase activity|cellobiose oxidase activity|phanerochaete chrysosporium cellobiose oxidoreductase activity|cellobiose:(acceptor) 1-oxidoreductase activity|CDH activity|CBOR activity|cellobiose:acceptor 1-oxidoreductase activity|cellobiose dehydrogenase (quinone) activity|cellobiose-quinone oxidoreductase activity|cellobiose dehydrogenase activity|cellobiose oxidoreductase activity										GO:0047737	RHEA:23484|EC:1.1.99.18|MetaCyc:CELLOBIOSE-DEHYDROGENASE-ACCEPTOR-RXN		molecular_function											owl:Class	
GO:0090473	biolink:NamedThing	lys-arg specific dibasic protein processing	Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein.	got7fsn_ti							tb	2012-10-01T10:42:30Z						biological_process											owl:Class	
GO:0050129	biolink:NamedThing	N-formylglutamate deformylase activity	Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate.	got7fsn_ti	beta-citryl-L-glutamate amidase activity|beta-citryl-L-glutamate amidohydrolase activity|beta-citryl-L-glutamate-hydrolyzing enzyme|N-formyl-L-glutamate amidohydrolase activity|beta-citryl-L-glutamate hydrolase activity|formylglutamate deformylase activity|N-formylglutamate hydrolase activity|beta-citrylglutamate amidase activity											EC:3.5.1.68|KEGG_REACTION:R00525|MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN|RHEA:12476		molecular_function											owl:Class	
GO:0004028	biolink:NamedThing	3-chloroallyl aldehyde dehydrogenase activity	Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.	got7fsn_ti												UM-BBD_enzymeID:e0432|Reactome:R-HSA-71260		molecular_function											owl:Class	
GO:0008117	biolink:NamedThing	sphinganine-1-phosphate aldolase activity	Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde.	got7fsn_ti	sphinganine-1-phosphate palmitaldehyde-lyase activity|sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)|sphingosine-1-phosphate aldolase activity|dihydrosphingosine 1-phosphate aldolase activity|sphinganine-1-phosphate alkanal-lyase activity|sphingosine-1-phosphate lyase activity|sphinganine-1-phosphate lyase activity										GO:0016001	EC:4.1.2.27|MetaCyc:SPHINGANINE-1-PHOSPHATE-ALDOLASE-RXN|Reactome:R-HSA-428681|RHEA:18593|Reactome:R-HSA-428676		molecular_function											owl:Class	
GO:0052926	biolink:NamedThing	dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.	got7fsn_ti	dolichylphosphomannose-dependent ALG9 mannosyltransferase activity											MetaCyc:RXN-5467|RHEA:29531|EC:2.4.1.259|KEGG_REACTION:R06259		molecular_function											owl:Class	
GO:0018246	biolink:NamedThing	protein-coenzyme A linkage	The formation of a linkage between a protein amino acid and coenzyme A.	got7fsn_ti														biological_process											owl:Class	
GO:0047028	biolink:NamedThing	6-pyruvoyltetrahydropterin 2'-reductase activity	Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin.	got7fsn_ti	6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity|pyruvoyl-tetrahydropterin reductase activity|6-pyruvoyl tetrahydropterin (2'-oxo)reductase activity|6-pyruvoyltetrahydropterin reductase activity|6-pyruvoyl-tetrahydropterin 2'-reductase activity|6PPH4(2'-oxo) reductase activity											RHEA:11772|MetaCyc:1.1.1.220-RXN|EC:1.1.1.220		molecular_function											owl:Class	
GO:0035476	biolink:NamedThing	angioblast cell migration	The orderly movement of angioblasts, cells involved in blood vessel morphogenesis.	got7fsn_ti							bf	2010-04-23T10:06:32Z						biological_process											owl:Class	
GO:1990970	biolink:NamedThing	trans-activation response element binding	Binding to a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter.	got7fsn_ti	TAR binding						bf	2016-06-21T12:23:00Z						molecular_function											owl:Class	
GO:0070883	biolink:NamedThing	pre-miRNA binding	Binding to a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.	got7fsn_ti	precursor microRNA binding|pre-microRNA binding						mah	2009-08-24T04:36:24Z						molecular_function											owl:Class	
GO:0090578	biolink:NamedThing	RNA polymerase V transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V.	got7fsn_ti	RNA polymerase V transcription factor complex						tb	2014-05-09T14:04:37Z						cellular_component											owl:Class	
GO:0052679	biolink:NamedThing	terpentetriene synthase activity	Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene.	got7fsn_ti	terpentedienyl-diphosphate diphosphate-lyase (terpentetriene-forming) activity											RHEA:25617|MetaCyc:RXN-9455|EC:4.2.3.36		molecular_function											owl:Class	
GO:0036304	biolink:NamedThing	umbilical cord morphogenesis	The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.	got7fsn_ti							bf	2012-08-08T10:12:11Z						biological_process											owl:Class	
GO:0075004	biolink:NamedThing	adhesion of symbiont spore to host	The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	adhesion of symbiont spore to host during symbiotic interaction				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0016202	biolink:NamedThing	regulation of striated muscle tissue development	Any process that modulates the frequency, rate or extent of striated muscle development.	got7fsn_ti														biological_process											owl:Class	
GO:0061922	biolink:NamedThing	histone propionyltransferase activity	Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone.	got7fsn_ti							dph	2017-08-02T13:38:50Z						molecular_function											owl:Class	
GO:0061920	biolink:NamedThing	protein propionyltransferase activity	Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide.	got7fsn_ti							dph	2017-08-02T13:35:22Z						molecular_function											owl:Class	
GO:0015386	biolink:NamedThing	potassium:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in).	got7fsn_ti	potassium:hydrogen antiporter activity											RHEA:29467		molecular_function											owl:Class	
GO:0071139	biolink:NamedThing	resolution of recombination intermediates	The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.	got7fsn_ti							mah	2009-11-16T12:02:21Z						biological_process											owl:Class	
GO:0047125	biolink:NamedThing	delta1-piperideine-2-carboxylate reductase activity	Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate.	got7fsn_ti	1,2-didehydropipecolate reductase activity|D1-piperideine-2-carboxylate reductase activity|L-pipecolate:NADP+ 2-oxidoreductase activity|delta 1-piperideine-2-carboxylate reductase activity|P2C reductase activity|1,2-didehydropipecolic reductase activity											RHEA:12524|MetaCyc:RXN-8166|EC:1.5.1.21		molecular_function											owl:Class	
GO:0097054	biolink:NamedThing	L-glutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid.	got7fsn_ti	L-glutamate synthesis|L-glutamate anabolism|L-glutamate formation|L-glutamate biosynthesis						pr	2011-05-24T04:30:38Z						biological_process											owl:Class	
GO:0071848	biolink:NamedThing	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling	Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade.	got7fsn_ti	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalling|positive regulation of ERK1 and ERK2 cascade via RANKL-mediated signaling						mah	2010-09-10T02:25:31Z						biological_process											owl:Class	
GO:0070374	biolink:NamedThing	positive regulation of ERK1 and ERK2 cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.	got7fsn_ti	activation of ERK1 and ERK2 cascade|positive regulation of ERK1 cascade|positive regulation of ERK2 cascade|up-regulation of ERK1 and ERK2 cascade|positive regulation of MAPK1 cascade|positive regulation of ERK1 and ERK2 signalling pathway|positive regulation of ERK cascade|positive regulation of ERK1/2 cascade|positive regulation of MAPK3 cascade|stimulation of ERK1 and ERK2 cascade|upregulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 signaling pathway|up regulation of ERK1 and ERK2 cascade													biological_process											owl:Class	
GO:0097005	biolink:NamedThing	adipokinetic hormone receptor binding	Binding to an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.	got7fsn_ti	AKH receptor binding						pr	2011-03-14T12:58:19Z						molecular_function											owl:Class	
GO:0047567	biolink:NamedThing	3-methyleneoxindole reductase activity	Catalysis of the reaction: 3-methyloxindole + NADP(+) = 3-methyleneoxindole + H(+) + NADPH.	got7fsn_ti	3-methyloxindole:NADP+ oxidoreductase activity|3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase activity											MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN|EC:1.3.1.17|KEGG_REACTION:R03930|RHEA:20257		molecular_function											owl:Class	
GO:0002210	biolink:NamedThing	behavioral response to wounding	A behavioral response resulting from wounding.	got7fsn_ti	behavioural response to wounding													biological_process											owl:Class	
GO:0009422	biolink:NamedThing	bacterial-type flagellum hook-filament junction	The region of the bacterial-type flagellum where the hook and filament meet.	got7fsn_ti	flagellar hook-filament junction													cellular_component											owl:Class	
GO:0034869	biolink:NamedThing	2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH.	got7fsn_ti												UM-BBD_reactionID:r1307		molecular_function											owl:Class	
GO:0036005	biolink:NamedThing	response to macrophage colony-stimulating factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.	got7fsn_ti	response to macrophage colony-stimulating factor|response to M-CSF|response to macrophage colony-stimulating factor stimulus						bf	2011-09-20T04:22:03Z						biological_process											owl:Class	
GO:0047129	biolink:NamedThing	opine dehydrogenase activity	Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H(2)O + NAD(+) = L-2-aminopentanoate + H(+) + NADH + pyruvate.	got7fsn_ti	(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate:NAD+ oxidoreductase (L-aminopentanoate-forming)|(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD, L-aminopentanoate-forming)											MetaCyc:1.5.1.28-RXN|RHEA:21592|EC:1.5.1.28|KEGG_REACTION:R03732		molecular_function											owl:Class	
GO:0042615	biolink:NamedThing	CD154 receptor binding	Binding to CD154, a receptor found on the surface of some activated lymphocytes.	got7fsn_ti	CD40 receptor activity|CD40L binding													molecular_function											owl:Class	
GO:0102576	biolink:NamedThing	3-oxo-palmitoyl-ACP hydrolase activity	Catalysis of the reaction: H2O + a 3-oxo-palmitoyl-[acp] = 3-oxopalmitic acid + H+ + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-15282		molecular_function											owl:Class	
GO:0071906	biolink:NamedThing	CRD domain binding	Binding to a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins.	got7fsn_ti	context dependent regulatory domain binding						mah	2010-09-21T04:08:53Z						molecular_function											owl:Class	
GO:0004067	biolink:NamedThing	asparaginase activity	Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.	got7fsn_ti	alpha-asparaginase activity|asparaginase II|crasnitin|leunase activity|elspar|L-asparaginase activity|L-asparagine amidohydrolase activity|colaspase activity											Reactome:R-HSA-6797627|EC:3.5.1.1|RHEA:21016|MetaCyc:ASPARAGHYD-RXN		molecular_function											owl:Class	
GO:0033790	biolink:NamedThing	hydroxymethylfurfural reductase activity	Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.	got7fsn_ti														molecular_function											owl:Class	
GO:0071585	biolink:NamedThing	detoxification of cadmium ion	Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.	got7fsn_ti							mah	2010-01-28T03:38:48Z						biological_process											owl:Class	
GO:0044874	biolink:NamedThing	lipoprotein localization to outer membrane	A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.	got7fsn_ti							jl	2014-11-25T16:30:30Z						biological_process											owl:Class	
GO:0019149	biolink:NamedThing	3-chloro-D-alanine dehydrochlorinase activity	Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3.	got7fsn_ti	3-chloro-D-alanine chloride-lyase (deaminating)|beta-chloro-D-alanine dehydrochlorinase activity|3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming)											RHEA:18873|MetaCyc:3-CHLORO-D-ALANINE-DEHYDROCHLORINASE-RXN|EC:4.5.1.2		molecular_function											owl:Class	
GO:0001108	biolink:NamedThing	bacterial-type RNA polymerase holo enzyme binding	Binding to a component of the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase.	got7fsn_ti	basal bacterial-type RNA polymerase transcription machinery binding						krc	2010-11-30T04:26:04Z						molecular_function											owl:Class	
GO:0008691	biolink:NamedThing	3-hydroxybutyryl-CoA dehydrogenase activity	Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.	got7fsn_ti	(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase activity|beta-hydroxybutyryl coenzyme A dehydrogenase activity|dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate)|BHBD activity|L-(+)-3-hydroxybutyryl-CoA dehydrogenase activity|L(+)-3-hydroxybutyryl-CoA dehydrogenase activity|beta-hydroxybutyryl-CoA dehydrogenase activity											EC:1.1.1.157|MetaCyc:3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN|RHEA:16197		molecular_function											owl:Class	
GO:0018985	biolink:NamedThing	pronuclear envelope synthesis	Synthesis and ordering of the envelope of pronuclei.	got7fsn_ti														biological_process											owl:Class	
GO:0047042	biolink:NamedThing	androsterone dehydrogenase (B-specific) activity	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.	got7fsn_ti	3-alpha-HSD activity|3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)|3alpha-hydroxysteroid oxidoreductase activity|3alpha-HSD|3-alpha-hydroxysteroid dehydrogenase (B-specific) activity|3alpha-hydroxysteroid dehydrogenase (B-specific)|sterognost 3alpha|hydroxyprostaglandin dehydrogenase activity											Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(B-specific)|EC:1.1.1.50|MetaCyc:1.1.1.50-RXN		molecular_function											owl:Class	
GO:0018498	biolink:NamedThing	2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity	Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate.	got7fsn_ti												UM-BBD_enzymeID:e0308|MetaCyc:PHENPRODIOLDEHYDROG-RXN|RHEA:25062		molecular_function											owl:Class	
GO:0061725	biolink:NamedThing	cytosolic lipolysis	The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.	got7fsn_ti							dph	2015-07-08T13:42:15Z						biological_process											owl:Class	
GO:0090251	biolink:NamedThing	protein localization involved in establishment of planar polarity	Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.	got7fsn_ti	protein localisation involved in establishment of planar polarity						tb	2010-01-22T11:31:32Z						biological_process											owl:Class	
GO:0086092	biolink:NamedThing	regulation of the force of heart contraction by cardiac conduction	A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled.	got7fsn_ti							dph	2011-11-29T01:26:41Z						biological_process											owl:Class	
GO:0055113	biolink:NamedThing	epiboly involved in gastrulation with mouth forming second	The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0002574	biolink:NamedThing	thrombocyte differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.	got7fsn_ti					Note that platelets are the non-nucleated mammalian functional equivalent of the nucleated thrombocytes of non-mammalian vertebrates and are sometimes also referred to as thrombocytes. Platelet formation in mammals is covered by the biological_process term platelet formation ; GO:0030220.									biological_process											owl:Class	
GO:0034697	biolink:NamedThing	response to prostaglandin I	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.	got7fsn_ti	response to prostaglandin I stimulus													biological_process											owl:Class	
GO:0070399	biolink:NamedThing	wall teichoic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.	got7fsn_ti	wall teichoic acid catabolism|wall teichoic acid breakdown|wall teichoic acid degradation													biological_process											owl:Class	
GO:0047281	biolink:NamedThing	dioxotetrahydropyrimidine phosphoribosyltransferase activity	Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine.	got7fsn_ti	dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase activity|dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase activity|dioxotetrahydropyrimidine-ribonucleotide diphosphorylase activity|dioxotetrahydropyrimidine phosphoribosyl transferase activity|2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity											RHEA:10232|EC:2.4.2.20|MetaCyc:2.4.2.20-RXN		molecular_function											owl:Class	
GO:1990157	biolink:NamedThing	DnaA-DnaB-DnaC complex	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation.	got7fsn_ti							bhm	2013-08-02T11:42:27Z						cellular_component											owl:Class	
GO:0120326	biolink:NamedThing	appressorium-mediated entry into host	Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	appressorium-mediated host invasion|appressorium-mediated penetration into host|appressorium-mediated invasion into host|appressorium-mediated host penetration	https://github.com/geneontology/go-ontology/issues/21505					krc	2021-08-04T00:48:35Z						biological_process											owl:Class	
GO:0050262	biolink:NamedThing	ribosylnicotinamide kinase activity	Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide.	got7fsn_ti	ribosylnicotinamide kinase (phosphorylating)|nicotinamide riboside kinase activity|ATP:N-ribosylnicotinamide 5'-phosphotransferase activity										GO:0000816	Reactome:R-HSA-8869627|Reactome:R-HSA-8869633|KEGG_REACTION:R02324|EC:2.7.1.22|MetaCyc:RIBOSYLNICOTINAMIDE-KINASE-RXN|RHEA:14017		molecular_function											owl:Class	
GO:0002283	biolink:NamedThing	neutrophil activation involved in immune response	The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	neutrophil activation during immune response													biological_process											owl:Class	
GO:0003360	biolink:NamedThing	brainstem development	The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.	got7fsn_ti							dph	2009-12-03T10:47:20Z						biological_process											owl:Class	
GO:0080141	biolink:NamedThing	regulation of jasmonic acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid.	got7fsn_ti							dhl	2009-05-19T04:28:39Z						biological_process											owl:Class	
GO:0042304	biolink:NamedThing	regulation of fatty acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.	got7fsn_ti	regulation of fatty acid biosynthesis|regulation of fatty acid anabolism|regulation of fatty acid synthesis|regulation of fatty acid formation													biological_process											owl:Class	
GO:0030790	biolink:NamedThing	chlorophenol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole.	got7fsn_ti	halogenated phenol O-methyltransferase activity|trichlorophenol O-methyltransferase activity|S-adenosyl-L-methionine:trichlorophenol O-methyltransferase activity											EC:2.1.1.136|MetaCyc:2.1.1.136-RXN|RHEA:18909		molecular_function											owl:Class	
GO:0034939	biolink:NamedThing	5-hydroxypyrrole-2-carboxylate tautomerase activity	Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate.	got7fsn_ti												UM-BBD_reactionID:r0969		molecular_function											owl:Class	
GO:0010542	biolink:NamedThing	nitrate efflux transmembrane transporter activity	Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti														molecular_function											owl:Class	
GO:0018781	biolink:NamedThing	S-triazine hydrolase activity	Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine.	got7fsn_ti												UM-BBD_enzymeID:e0091		molecular_function											owl:Class	
GO:0110068	biolink:NamedThing	glucosylglycerate phosphorylase activity	Catalysis of the reaction: glucosylglycerate + phosphate = glucose-1-phosphate + D-glycerate.	got7fsn_ti							kmv	2017-11-21T21:50:10Z						molecular_function											owl:Class	
GO:0062047	biolink:NamedThing	pipecolic acid N-hydroxylase	Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O.	got7fsn_ti							dph	2018-05-11T12:17:15Z						molecular_function											owl:Class	
GO:0016078	biolink:NamedThing	tRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.	got7fsn_ti	tRNA degradation|tRNA breakdown|tRNA catabolism													biological_process											owl:Class	
GO:0033010	biolink:NamedThing	paranodal junction	A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.	got7fsn_ti	paranodal axoglial junction|paranodal septate junction|axoglial septate junction													cellular_component											owl:Class	
GO:0035704	biolink:NamedThing	helper T cell chemotaxis	The directed movement of a helper T cell in response to an external stimulus.	got7fsn_ti	T-helper cell chemotaxis						bf	2011-03-02T02:31:48Z						biological_process											owl:Class	
GO:1990889	biolink:NamedThing	H4K20me3 modified histone binding	Binding to a histone H4 in which the lysine residue at position 20 has been modified by trimethylation.	got7fsn_ti							al	2015-10-30T15:43:09Z						molecular_function											owl:Class	
GO:0102820	biolink:NamedThing	norbixin methyltransferase activity	Catalysis of the reaction: norbixin + S-adenosyl-L-methionine  <=> bixin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-8238		molecular_function											owl:Class	
GO:0009381	biolink:NamedThing	excinuclease ABC activity	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind.	got7fsn_ti														molecular_function											owl:Class	
GO:0034602	biolink:NamedThing	oxoglutarate dehydrogenase (NAD+) activity	Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH.	got7fsn_ti												Reactome:R-HSA-71037|Reactome:R-HSA-71401|KEGG_REACTION:R08549|EC:1.2.1.105|MetaCyc:2OXOGLUTARATEDEH-RXN|RHEA:27786		molecular_function											owl:Class	
GO:1900803	biolink:NamedThing	brevianamide F metabolic process	The chemical reactions and pathways involving brevianamide F.	got7fsn_ti	L-tryptophyl-L-proline cyclic anhydride metabolism|tryptophan-proline diketopiperazine metabolic process|cyclo-L-tryptophanyl-L-proline metabolism|L-prolyl-L-tryptophan anhydride metabolic process|cyclo-(Trp-Pro) metabolism|cyclo-L-Trp-L-Pro metabolic process|cyclo-L-Trp-L-Pro metabolism|cyclo-L-tryptophanyl-L-proline metabolic process|brevianamide F metabolism|L-tryptophyl-L-proline cyclic anhydride metabolic process|tryptophan-proline diketopiperazine metabolism|L-prolyl-L-tryptophan anhydride metabolism						di	2012-06-04T09:52:19Z						biological_process											owl:Class	
GO:0036394	biolink:NamedThing	amylase secretion	The controlled release of amylase from a cell.	got7fsn_ti	amylase release						bf	2013-07-01T13:03:19Z						biological_process											owl:Class	
GO:0071042	biolink:NamedThing	nuclear polyadenylation-dependent mRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.	got7fsn_ti	nuclear poly(A)-dependent mRNA catabolic process						krc	2009-07-29T02:06:19Z						biological_process											owl:Class	
GO:0042989	biolink:NamedThing	sequestering of actin monomers	The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers.	got7fsn_ti	actin monomer sequestering|actin monomer sequestration|sequestration of actin monomers|actin monomer storage|retention of actin monomers|actin monomer sequestering activity|storage of actin monomers|actin monomer retention													biological_process											owl:Class	
GO:0102282	biolink:NamedThing	3-ketodihydrosphinganine (C18) reductase activity	Catalysis of the reaction: NAD(1-) + a sphinganine <=> 3-dehydrosphinganinium(1+) + NADH + H+.	got7fsn_ti												MetaCyc:RXN-12641		molecular_function											owl:Class	
GO:0033475	biolink:NamedThing	indoleacetic acid amide conjugate biosynthetic process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond.	got7fsn_ti	indoleacetic acid amide conjugate biosynthesis|indoleacetic acid amide conjugate formation|indole acetic acid amide conjugate biosynthetic process|indole acetic acid amide conjugate biosynthesis|indoleacetic acid amide conjugate synthesis|IAA amide conjugate biosynthetic process|indoleacetic acid amide conjugate anabolism											MetaCyc:PWY-1782		biological_process											owl:Class	
GO:0035310	biolink:NamedThing	notum cell fate specification	The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.	got7fsn_ti														biological_process											owl:Class	
GO:0036345	biolink:NamedThing	platelet maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.	got7fsn_ti							bf	2012-09-11T15:23:11Z						biological_process											owl:Class	
GO:0098680	biolink:NamedThing	template-free RNA nucleotidyltransferase	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template.	got7fsn_ti							dos	2017-01-31T15:51:56Z						molecular_function											owl:Class	
GO:1905276	biolink:NamedThing	regulation of epithelial tube formation	Any process that modulates the frequency, rate or extent of epithelial tube formation.	got7fsn_ti					An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-06-20T09:35:41Z						biological_process											owl:Class	
GO:0097090	biolink:NamedThing	presynaptic membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.	got7fsn_ti	pre-synaptic membrane organization|presynaptic membrane organisation				Note that 'presynaptic membrane' in this term should not be mistaken with 'presynaptic active zone'. The latter encompasses more than the former, as it also includes the specialized cortical cytoskeletal matrix in the cell cortex of a presynaptic neuron.		pr	2011-07-04T01:45:30Z						biological_process											owl:Class	
GO:0008801	biolink:NamedThing	beta-phosphoglucomutase activity	Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.	got7fsn_ti	beta-D-glucose 1,6-phosphomutase activity											KEGG_REACTION:R02728|EC:5.4.2.6|MetaCyc:BETA-PHOSPHOGLUCOMUTASE-RXN|RHEA:20113		molecular_function											owl:Class	
GO:0050619	biolink:NamedThing	phytochromobilin:ferredoxin oxidoreductase activity	Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.	got7fsn_ti	PPhiB synthase activity|PFB synthase activity|HY2|phytochromobilin synthase activity|(3Z)-phytochromobilin:ferredoxin oxidoreductase activity|P-Phi-B synthase activity											RHEA:16377|EC:1.3.7.4|MetaCyc:1.3.7.4-RXN		molecular_function											owl:Class	
GO:0005316	biolink:NamedThing	high-affinity inorganic phosphate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity inorganic phosphate:sodium symporter activity|sodium/phosphate cotransporter activity													molecular_function											owl:Class	
GO:0005436	biolink:NamedThing	sodium:phosphate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).	got7fsn_ti	sodium/phosphate symporter activity|sodium-dependent phosphate transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/18577									GO:0015321	Reactome:R-HSA-5625123|Reactome:R-HSA-5687585|Reactome:R-HSA-5651697|Reactome:R-HSA-2872498|Reactome:R-HSA-427645|Reactome:R-HSA-428609|Reactome:R-HSA-5651971|Reactome:R-HSA-427656|Reactome:R-HSA-427605|Reactome:R-HSA-5651685		molecular_function											owl:Class	
GO:0070194	biolink:NamedThing	synaptonemal complex disassembly	The controlled breakdown of a synaptonemal complex.	got7fsn_ti														biological_process											owl:Class	
GO:0047951	biolink:NamedThing	glutathione thiolesterase activity	Catalysis of the reaction: S-acylglutathione + H(2)O = a carboxylate + glutathione + H(+).	got7fsn_ti	S-acylglutathione hydrolase activity|glutathione thioesterase activity|citryl-glutathione thioesterhydrolase activity											MetaCyc:GLUTATHIONE-THIOESTERASE-RXN|KEGG_REACTION:R00547|RHEA:22708|EC:3.1.2.7		molecular_function											owl:Class	
GO:0046129	biolink:NamedThing	purine ribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	purine ribonucleoside synthesis|purine ribonucleoside formation|purine ribonucleoside biosynthesis|purine ribonucleoside anabolism													biological_process											owl:Class	
GO:0003355	biolink:NamedThing	cilium movement involved in otolith formation	The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles.	got7fsn_ti							dph	2009-12-03T10:21:08Z						biological_process											owl:Class	
GO:0014885	biolink:NamedThing	detection of injury involved in regulation of muscle adaptation	The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.	got7fsn_ti	detection of injury involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0014876	biolink:NamedThing	response to injury involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.	got7fsn_ti	response to injury involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0033191	biolink:NamedThing	macrophomate synthase activity	Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate.	got7fsn_ti														molecular_function											owl:Class	
GO:0045208	biolink:NamedThing	MAPK phosphatase export from nucleus	The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm.	got7fsn_ti	MAPK phosphatase export from cell nucleus|MAPK phosphatase export out of nucleus|MAPK phosphatase transport from nucleus to cytoplasm|MAPK phosphatase-nucleus export													biological_process											owl:Class	
GO:0046820	biolink:NamedThing	4-amino-4-deoxychorismate synthase activity	Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.	got7fsn_ti	aminodeoxychorismate synthase activity|para-aminobenzoic acid synthase activity|PabB activity|para-aminobenzoic acid (PABA) synthase|p-aminobenzoate synthetase|ADC synthase activity|chorismate:L-glutamine amido-ligase activity				Note that the name 'para-aminobenzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate.							RHEA:11672|EC:2.6.1.85|KEGG_REACTION:R01716|MetaCyc:PABASYN-RXN		molecular_function											owl:Class	
GO:0046915	biolink:NamedThing	transition metal ion transmembrane transporter activity	Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	got7fsn_ti														molecular_function											owl:Class	
GO:0004044	biolink:NamedThing	amidophosphoribosyltransferase activity	Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.	got7fsn_ti	glutamine phosphoribosylpyrophosphate amidotransferase activity|phosphoribose pyrophosphate amidotransferase activity|glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity|5-phosphoribosyl-1-pyrophosphate amidotransferase activity|glutamine phosphoribosyldiphosphate amidotransferase activity|alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity|5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)|phosphoribosyl pyrophosphate amidotransferase activity|phosphoribosylpyrophosphate glutamyl amidotransferase activity|5'-phosphoribosylpyrophosphate amidotransferase activity|5-phosphororibosyl-1-pyrophosphate amidotransferase activity|phosphoribosyldiphosphate 5-amidotransferase activity|glutamine 5-phosphoribosylpyrophosphate amidotransferase activity											RHEA:14905|EC:2.4.2.14|Reactome:R-HSA-73815|KEGG_REACTION:R01072|MetaCyc:PRPPAMIDOTRANS-RXN		molecular_function											owl:Class	
GO:0106019	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.	got7fsn_ti							hjd	2017-05-10T14:22:12Z						molecular_function											owl:Class	
GO:0003139	biolink:NamedThing	secondary heart field specification	The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).	got7fsn_ti	anterior heart field specification|second heart field specification|SHF specification						tb	2009-09-22T03:47:56Z						biological_process											owl:Class	
GO:0106268	biolink:NamedThing	3,5-dichloro-THPH methyl transferase activity	Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine.	got7fsn_ti	DIF-1 syntase						hjd	2020-06-02T18:25:03Z				RHEA:48396		molecular_function											owl:Class	
GO:0099047	biolink:NamedThing	clearance of foreign intracellular RNA	A defense process that protects an organism from invading foreign RNA.	got7fsn_ti														biological_process											owl:Class	
GO:0050357	biolink:NamedThing	tropinesterase activity	Catalysis of the reaction: atropine + H(2)O = H(+) + tropate + tropine.	got7fsn_ti	atropine esterase activity|atropine acylhydrolase activity|tropine esterase activity|atropinesterase activity|atropinase activity											MetaCyc:TROPINESTERASE-RXN|RHEA:23304|KEGG_REACTION:R03563|EC:3.1.1.10		molecular_function											owl:Class	
GO:0006529	biolink:NamedThing	asparagine biosynthetic process	The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid.	got7fsn_ti	asparagine biosynthesis|asparagine formation|asparagine anabolism|asparagine synthesis													biological_process											owl:Class	
GO:0005673	biolink:NamedThing	transcription factor TFIIE complex	A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH.	got7fsn_ti														cellular_component											owl:Class	
GO:0044677	biolink:NamedThing	methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex	A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis.	got7fsn_ti	N5-methyltetrahydromethanopterin-coenzyme M methyltransferase complex|methyl-H4MPT|coenzyme M methyltransferase complex|5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethane sulfonate 2-methyltransferase complex						jl	2012-08-09T10:58:24Z						cellular_component											owl:Class	
GO:0098983	biolink:NamedThing	symmetric, GABA-ergic, inhibitory synapse	A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.	got7fsn_ti														cellular_component											owl:Class	
GO:0102778	biolink:NamedThing	Delta9-tetrahydrocannabinolate synthase activity	Catalysis of the reaction: cannabigerolate + O2 <=> Delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide.	got7fsn_ti												EC:1.21.3.7|RHEA:34135|MetaCyc:RXN-7854		molecular_function											owl:Class	
GO:0001851	biolink:NamedThing	complement component C3b binding	Binding to a C3b product of the complement cascade.	got7fsn_ti														molecular_function											owl:Class	
GO:0044027	biolink:NamedThing	hypermethylation of CpG island	An increase in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.	got7fsn_ti	DNA hypermethylation of CpG island													biological_process											owl:Class	
GO:0071765	biolink:NamedThing	nuclear inner membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.	got7fsn_ti	nuclear inner membrane organization and biogenesis|nuclear inner membrane organisation						mah	2010-03-29T04:04:57Z						biological_process											owl:Class	
GO:0097496	biolink:NamedThing	blood vessel lumen ensheathment	A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel.	got7fsn_ti							pr	2013-08-12T13:46:45Z						biological_process											owl:Class	
GO:0050520	biolink:NamedThing	phosphatidylcholine synthase activity	Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+).	got7fsn_ti	PC synthase activity|CDP-diacylglycerol:choline O-phosphatidyltransferase activity|CDP-diglyceride-choline O-phosphatidyltransferase activity|CDPdiglyceride-choline O-phosphatidyltransferase activity											KEGG_REACTION:R05794|EC:2.7.8.24|MetaCyc:2.7.8.24-RXN|RHEA:14597		molecular_function											owl:Class	
GO:0033975	biolink:NamedThing	(R)-2-haloacid dehalogenase activity	Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.	got7fsn_ti	D-DEX|2-haloalkanoic acid dehalogenase activity|D-2-haloacid dehalogenase activity|2-haloalkanoid acid halidohydrolase activity|(R)-2-haloacid halidohydrolase activity											MetaCyc:3.8.1.9-RXN|EC:3.8.1.9		molecular_function											owl:Class	
GO:0060662	biolink:NamedThing	salivary gland cavitation	The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland.	got7fsn_ti	salivary gland invagination						dph	2009-06-01T08:22:55Z						biological_process											owl:Class	
GO:0102028	biolink:NamedThing	cystathionine gamma-synthase activity (acts on O-phosphohomoserine)	Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate.	got7fsn_ti												EC:2.5.1.48|MetaCyc:CYSPH-RXN		molecular_function											owl:Class	
GO:0050438	biolink:NamedThing	2-ethylmalate synthase activity	Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H(2)O = (R)-2-ethylmalate + CoA + H(+).	got7fsn_ti	(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating) activity|propylmalate synthase activity|acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|propylmalic synthase activity|2-ethylmalate-3-hydroxybutanedioate synthase activity											MetaCyc:2-ETHYLMALATE-SYNTHASE-RXN|KEGG_REACTION:R00998|RHEA:23040|EC:2.3.3.6		molecular_function											owl:Class	
GO:0044479	biolink:NamedThing	envenomation resulting in modulation of mast cell degranulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:51:51Z						biological_process											owl:Class	
GO:0009235	biolink:NamedThing	cobalamin metabolic process	The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	got7fsn_ti	vitamin B12 metabolism|cobalamin metabolism|vitamin B12 reduction|vitamin B12 metabolic process													biological_process											owl:Class	
GO:0050264	biolink:NamedThing	rifamycin-B oxidase activity	Catalysis of the reaction: 2 H(+) + O(2) + rifamycin B = H(2)O(2) + rifamycin O.	got7fsn_ti	rifamycin B oxidase activity|rifamycin-B-oxidase activity|rifamycin-B:oxygen oxidoreductase activity											KEGG_REACTION:R03736|MetaCyc:RIFAMYCIN-B-OXIDASE-RXN|RHEA:11292|EC:1.10.3.6		molecular_function											owl:Class	
GO:0070921	biolink:NamedThing	regulation of production of siRNA involved in gene silencing by small RNA	Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of gene silencing by small RNA.	got7fsn_ti	regulation of production of siRNA involved in chromatin silencing by small RNA|regulation of chromatin silencing by small RNA, production of siRNA	https://github.com/geneontology/go-ontology/issues/22058					mah	2009-09-11T03:42:51Z						biological_process											owl:Class	
GO:0035682	biolink:NamedThing	toll-like receptor 21 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 21.	got7fsn_ti	toll-like receptor 21 signalling pathway|TLR21 signaling pathway						bf	2011-02-21T02:39:39Z						biological_process											owl:Class	
GO:0018844	biolink:NamedThing	2-hydroxytetrahydrofuran isomerase activity	Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde.	got7fsn_ti												EC:5.3.99.-|UM-BBD_reactionID:r0019		molecular_function											owl:Class	
GO:0090728	biolink:NamedThing	negative regulation of brood size	Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.	got7fsn_ti							tb	2016-12-19T15:07:32Z						biological_process											owl:Class	
GO:0007479	biolink:NamedThing	leg disc proximal/distal pattern formation	The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.	got7fsn_ti														biological_process											owl:Class	
GO:0102064	biolink:NamedThing	gamma-curcumene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> gamma-curcumene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10599|RHEA:32031|EC:4.2.3.94		molecular_function											owl:Class	
GO:0043451	biolink:NamedThing	alkene catabolic process	The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.	got7fsn_ti	alkene breakdown|alkene catabolism|alkene degradation													biological_process											owl:Class	
GO:0070554	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).	got7fsn_ti	SNARE complex (Stx3, Snap25, Vamp2, Cplx1)|Stx3-Snap25-Vamp2-Cplx1 complex													cellular_component											owl:Class	
GO:0102919	biolink:NamedThing	5,6-dimethylbenzimidazole synthase activity	Catalysis of the reaction: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialuric acid.	got7fsn_ti												RHEA:27345|EC:1.13.11.79|MetaCyc:RXN-8771		molecular_function											owl:Class	
GO:0031444	biolink:NamedThing	slow-twitch skeletal muscle fiber contraction	A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.	got7fsn_ti	slow-twitch skeletal muscle fibre contraction													biological_process											owl:Class	
GO:0047228	biolink:NamedThing	1,2-diacylglycerol 3-glucosyltransferase activity	Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP.	got7fsn_ti	UDPglucose:diacylglycerol glucosyltransferase activity|UDPglucose:1,2-diacylglycerol 3-D-glucosyltransferase activity|UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase activity|UDP-glucose:1,2-diacylglycerol glucosyltransferase activity|UDP-glucose-diacylglycerol glucosyltransferase activity|uridine diphosphoglucose-diacylglycerol glucosyltransferase activity											EC:2.4.1.157|MetaCyc:2.4.1.157-RXN		molecular_function											owl:Class	
GO:0008012	biolink:NamedThing	structural constituent of adult chitin-based cuticle	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster.	got7fsn_ti	structural constituent of adult cuticle													molecular_function											owl:Class	
GO:0047380	biolink:NamedThing	ADP-dependent medium-chain-acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. Requires ADP.	got7fsn_ti	ADP-dependent-medium-chain-acyl-CoA hydrolase activity|ADP-dependent myristoyl-CoA thioesterase activity|ADP-dependent medium-chain acyl-CoA hydrolase activity|ADP-dependent medium-chain acyl coenzyme A hydrolase activity|ADP-dependent medium-chain acyl-thioester hydrolase activity|ADP-dependent medium-chain hydrolase activity											MetaCyc:3.1.2.19-RXN|EC:3.1.2.19		molecular_function											owl:Class	
GO:0001019	biolink:NamedThing	plastid promoter transcription regulatory region sequence-specific DNA binding	Binding to a DNA region that controls transcription by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.	got7fsn_ti					plastid promoter regulatory region sequence-specific DNA binding		krc	2010-08-19T09:46:27Z						molecular_function											owl:Class	
GO:0039595	biolink:NamedThing	induction by virus of catabolism of host mRNA	The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA).	got7fsn_ti	virus-mediated mRNA decay|induction by virus of host mRNA catabolic process|promotion of host mRNA degradation|induction of host mRNA decay|viral induction of host mRNA decay						bf	2012-07-04T03:14:04Z				VZ:901		biological_process											owl:Class	
GO:0061014	biolink:NamedThing	positive regulation of mRNA catabolic process	Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.	got7fsn_ti	positive regulation of mRNA decay						dph	2010-01-29T01:58:03Z						biological_process											owl:Class	
GO:0072259	biolink:NamedThing	metanephric interstitial fibroblast development	The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure.	got7fsn_ti	metanephros interstitial cell development						mah	2010-03-19T04:18:00Z						biological_process											owl:Class	
GO:0097719	biolink:NamedThing	neural tissue regeneration	The regrowth of neural tissue following its loss or destruction.	got7fsn_ti	neuroregeneration						pr	2016-08-25T13:14:27Z						biological_process											owl:Class	
GO:0072492	biolink:NamedThing	host cell mitochondrial intermembrane space	The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope.	got7fsn_ti							mah	2010-12-15T11:44:02Z						cellular_component											owl:Class	
GO:0070191	biolink:NamedThing	methionine-R-sulfoxide reductase activity	Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin.	got7fsn_ti														molecular_function											owl:Class	
GO:0021972	biolink:NamedThing	corticospinal neuron axon guidance through spinal cord	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.	got7fsn_ti	corticospinal neuron axon pathfinding through spinal cord													biological_process											owl:Class	
GO:0140290	biolink:NamedThing	peptidyl-serine ADP-deribosylation	The removal of ADP-ribose from ADP-ribosylserine.	got7fsn_ti							pg	2018-11-22T14:32:30Z						biological_process											owl:Class	
GO:0051725	biolink:NamedThing	protein de-ADP-ribosylation	The process of removing one or more ADP-ribose residues from a protein.	got7fsn_ti	protein poly(ADP-ribose) catabolism|protein poly(ADP-ribose) degradation|protein poly(ADP-ribose) hydrolysis|poly(ADP-ribose) removal from protein|protein poly(ADP-ribose) catabolic process|protein amino acid de-ADP-ribosylation|removal of ADP-ribose from protein													biological_process											owl:Class	
GO:0008379	biolink:NamedThing	thioredoxin peroxidase activity	Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.	got7fsn_ti	TrxPx activity|thiol peroxidase activity|TPx activity										GO:0009031	RHEA:63528|Reactome:R-HSA-3697882|Reactome:R-HSA-3341343|Reactome:R-HSA-3697894|Reactome:R-HSA-2161612|MetaCyc:RXN0-267|Reactome:R-HSA-3322995		molecular_function											owl:Class	
GO:0044861	biolink:NamedThing	protein transport into plasma membrane raft	The directed movement of a protein into a plasma membrane raft.	got7fsn_ti							jl	2014-07-23T16:26:29Z						biological_process											owl:Class	
GO:0045272	biolink:NamedThing	plasma membrane respiratory chain complex I	A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species.	got7fsn_ti	NADH dehydrogenase (ubiquinone) complex|respiratory chain complex I													cellular_component											owl:Class	
GO:0047143	biolink:NamedThing	chlorate reductase activity	Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H(2)O + H(+).	got7fsn_ti	chlorate reductase C|chlorite:acceptor oxidoreductase activity											EC:1.97.1.1|KEGG_REACTION:R03575|MetaCyc:1.97.1.1-RXN|UM-BBD_reactionID:r0981|RHEA:16349		molecular_function											owl:Class	
GO:0090408	biolink:NamedThing	phloem nitrate loading	The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink.	got7fsn_ti							tb	2011-06-01T10:06:21Z						biological_process											owl:Class	
GO:0052897	biolink:NamedThing	N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: H(2)O + N(8)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2).	got7fsn_ti	N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming) activity											RHEA:25972|EC:1.5.3.15|KEGG_REACTION:R09075|MetaCyc:RXN-10463		molecular_function											owl:Class	
GO:0004571	biolink:NamedThing	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.	got7fsn_ti	Man9-mannosidase activity|mannosidase I|mannosidase 1A activity|exo-alpha-1,2-mannanase activity|1,2-alpha-mannosidase|glycoprotein processing mannosidase I|man9-mannosidase activity|1,2-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|mannose-9 processing alpha-mannosidase activity|ManI activity|mannosidase 1B activity											Reactome:R-HSA-9036008|Reactome:R-HSA-901074|EC:3.2.1.113|Reactome:R-HSA-6782685|Reactome:R-HSA-9036012|MetaCyc:3.2.1.113-RXN|Reactome:R-HSA-901039|Reactome:R-HSA-901024|KEGG_REACTION:R06722|Reactome:R-HSA-9696807|Reactome:R-HSA-964825|KEGG_REACTION:R05982|Reactome:R-HSA-901036|Reactome:R-HSA-4793949|Reactome:R-HSA-9036011|Reactome:R-HSA-964737|Reactome:R-HSA-964830		molecular_function											owl:Class	
GO:0033110	biolink:NamedThing	Cvt vesicle membrane	Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway.	got7fsn_ti	cytoplasm to vacuole targeting vesicle membrane|cytoplasm-to-vacuole targeting vesicle membrane													cellular_component											owl:Class	
GO:0042620	biolink:NamedThing	poly(3-hydroxyalkanoate) metabolic process	The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.	got7fsn_ti	poly(3-hydroxyalkanoate) metabolism|PHA metabolic process|PHA metabolism													biological_process											owl:Class	
GO:0022874	biolink:NamedThing	protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	cellobiose PTS transporter activity													molecular_function											owl:Class	
GO:0030047	biolink:NamedThing	actin modification	Covalent modification of an actin molecule.	got7fsn_ti											GO:0007013			biological_process											owl:Class	
GO:0050837	biolink:NamedThing	peptide cross-linking via L-cysteinyl-L-selenocysteine	The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P.	got7fsn_ti												RESID:AA0358		biological_process											owl:Class	
GO:0070502	biolink:NamedThing	capsule poly-gamma-glutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.	got7fsn_ti	capsule poly-gamma-glutamate biosynthesis|capsule poly-gamma-glutamate formation|capsule poly-gamma-glutamate synthesis|capsule poly-gamma-glutamate anabolism|capsular poly-gamma-glutamate biosynthetic process													biological_process											owl:Class	
GO:0008937	biolink:NamedThing	ferredoxin-NAD(P) reductase activity	Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+.	got7fsn_ti	ferredoxin reductase activity													molecular_function											owl:Class	
GO:0016731	biolink:NamedThing	oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP.	got7fsn_ti												EC:1.18.1.-		molecular_function											owl:Class	
GO:0045312	biolink:NamedThing	nor-spermidine biosynthetic process	The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	got7fsn_ti	nor-spermidine synthesis|nor-spermidine formation|nor-spermidine biosynthesis|nor-spermidine anabolism													biological_process											owl:Class	
GO:0021555	biolink:NamedThing	midbrain-hindbrain boundary morphogenesis	The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	got7fsn_ti	MHB morphogenesis|isthmus morphogenesis													biological_process											owl:Class	
GO:0090590	biolink:NamedThing	protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in).	got7fsn_ti							tb	2014-06-04T16:33:01Z						molecular_function											owl:Class	
GO:0061412	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of amino acids.	got7fsn_ti							dph	2012-01-12T12:54:05Z						biological_process											owl:Class	
GO:0015888	biolink:NamedThing	thiamine transport	The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.	got7fsn_ti	vitamin B1 transport|thiamin transport													biological_process											owl:Class	
GO:0098512	biolink:NamedThing	detection of humidity stimulus involved in sensory perception	The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity.	got7fsn_ti							dos	2013-09-25T14:09:25Z						biological_process											owl:Class	
GO:0016361	biolink:NamedThing	activin receptor activity, type I	Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals.	got7fsn_ti	type I activin receptor activity													molecular_function											owl:Class	
GO:0061700	biolink:NamedThing	GATOR2 complex	A multiprotein subcomplex of the GATOR complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, this complex consists of WDR24, WDR59, MIOS, SEH1L, and SEC13. In S. cerevisiae, this complex is referred to as SEACAT and contains the Sea2p, Sea3p, Sea4p, Seh1p, Sec13p proteins.	got7fsn_ti	SEACAT complex				The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ;  GO:1990131.		dph	2015-05-07T11:13:27Z						cellular_component											owl:Class	
GO:0043276	biolink:NamedThing	anoikis	Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix.	got7fsn_ti	detachment induced cell death|suspension induced apoptosis											Wikipedia:Anoikis		biological_process											owl:Class	
GO:0052005	biolink:NamedThing	suppression by symbiont of host ethylene-mediated defense response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	downregulation by symbiont of host ethylene-mediated defense response|negative regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|suppression by organism of host ethylene-mediated defense response|negative regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|negative regulation by symbiont of host ethylene-mediated defense response|down regulation by symbiont of host ethylene-mediated defense response|negative regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|down-regulation by symbiont of host ethylene-mediated defense response|inhibition by symbiont of host ethylene-mediated defense response										GO:0052268|GO:0052070|GO:0052254			biological_process											owl:Class	
GO:0097012	biolink:NamedThing	response to granulocyte macrophage colony-stimulating factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.	got7fsn_ti	response to GM-CSF|response to granulocyte macrophage colony-stimulating factor stimulus						pr	2011-03-22T01:12:15Z						biological_process											owl:Class	
GO:0080023	biolink:NamedThing	3R-hydroxyacyl-CoA dehydratase activity	Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O.	got7fsn_ti												Reactome:R-HSA-5676637		molecular_function											owl:Class	
GO:0043874	biolink:NamedThing	acireductone synthase activity	Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.	got7fsn_ti	5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing)|E-1|E-1 enolase-phosphatase				This function is involved in the process of methionine salvage.							EC:3.1.3.77|MetaCyc:3.1.3.77-RXN|RHEA:21700|Reactome:R-HSA-1237129		molecular_function											owl:Class	
GO:0044192	biolink:NamedThing	host cell mitochondrial inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae.	got7fsn_ti							jl	2009-10-15T04:17:29Z						cellular_component											owl:Class	
GO:1901271	biolink:NamedThing	lipooligosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of lipooligosaccharide.	got7fsn_ti	lipooligosaccharide synthesis|lipooligosaccharide biosynthesis|lipooligosaccharide anabolism|lipooligosaccharide formation						yaf	2012-08-17T14:31:55Z						biological_process											owl:Class	
GO:0050364	biolink:NamedThing	tryptophan dimethylallyltransferase activity	Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan.	got7fsn_ti	DMAT synthetase activity|dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase activity|dimethylallylpyrophosphate:tryptophan dimethylallyl transferase activity|dimethylallyltryptophan synthetase activity|dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase activity|4-(gamma,gamma-dimethylallyl)tryptophan synthase activity											RHEA:14173|MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN|EC:2.5.1.34		molecular_function											owl:Class	
GO:0031702	biolink:NamedThing	type 1 angiotensin receptor binding	Binding to a type 1 angiotensin receptor.	got7fsn_ti	AT1 receptor binding|type 1 angiotensin receptor ligand													molecular_function											owl:Class	
GO:0036205	biolink:NamedThing	histone catabolic process	The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.	got7fsn_ti	histone protein catabolic process				This term was created even though it describes a process relating to a group of gene products, because histones are highly conserved proteins that are essential components of cellular chromatin in eukaryotic cells.		bf	2012-04-24T04:48:48Z						biological_process											owl:Class	
GO:0032419	biolink:NamedThing	extrinsic component of lysosome membrane	The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to lysosomal membrane|extrinsic to lysosome membrane													cellular_component											owl:Class	
GO:0061722	biolink:NamedThing	sulphoglycolysis	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate.	got7fsn_ti	sulfoglycolysis						dph	2015-07-01T09:44:30Z						biological_process											owl:Class	
GO:1903296	biolink:NamedThing	positive regulation of glutamate secretion, neurotransmission	Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter.	got7fsn_ti	activation of glutamate secretion, neurotransmission|up regulation of glutamate secretion, neurotransmission|upregulation of glutamate secretion, neurotransmission|up-regulation of glutamate secretion, neurotransmission				An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype		pad	2014-08-13T13:54:31Z						biological_process											owl:Class	
GO:0050930	biolink:NamedThing	induction of positive chemotaxis	Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	got7fsn_ti														biological_process											owl:Class	
GO:0050927	biolink:NamedThing	positive regulation of positive chemotaxis	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	got7fsn_ti	upregulation of positive chemotaxis|up-regulation of positive chemotaxis|stimulation of positive chemotaxis|up regulation of positive chemotaxis|activation of positive chemotaxis													biological_process											owl:Class	
GO:0070586	biolink:NamedThing	cell-cell adhesion involved in gastrulation	The attachment of one cell to another cell affecting gastrulation.	got7fsn_ti							mah	2009-04-24T02:48:23Z						biological_process											owl:Class	
GO:0035407	biolink:NamedThing	histone H3-T11 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone.	got7fsn_ti							bf	2010-03-24T10:12:01Z						biological_process											owl:Class	
GO:0120134	biolink:NamedThing	proximal portion of axoneme	The portion of the axoneme that is close to the base of the cilium.	got7fsn_ti	proximal part of axoneme						krc	2018-03-10T01:41:06Z						cellular_component											owl:Class	
GO:0031782	biolink:NamedThing	type 4 melanocortin receptor binding	Binding to a type 4 melanocortin receptor.	got7fsn_ti	type 4 melanocortin receptor ligand													molecular_function											owl:Class	
GO:0039641	biolink:NamedThing	viral inner membrane	The lipid bilayer of a virion contained inside the protein capsid.	got7fsn_ti	virion inner membrane						bf	2012-09-07T13:29:48Z						cellular_component											owl:Class	
GO:2001290	biolink:NamedThing	hydroperoxide metabolic process	The chemical reactions and pathways involving a hydroperoxide.	got7fsn_ti	hydroperoxide metabolism						pr	2012-02-09T03:35:37Z						biological_process											owl:Class	
GO:0033822	biolink:NamedThing	glucosyl-DNA beta-glucosyltransferase activity	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA.	got7fsn_ti	T6-beta-glucosyl transferase activity|T6-glucosyl-HMC-beta-glucosyl transferase activity|uridine diphosphoglucose-glucosyldeoxyribonucleate beta-glucosyltransferase activity|UDPglucose:D-glucosyl-DNA beta-D-glucosyltransferase activity|UDP-glucose:D-glucosyl-DNA beta-D-glucosyltransferase activity											EC:2.4.1.28|MetaCyc:2.4.1.28-RXN		molecular_function											owl:Class	
GO:0102113	biolink:NamedThing	hypoxia-inducible factor-asparagine oxygenase activity	Catalysis of the reaction: 2-oxoglutarate + O2 + a hypoxia inducible factor (HIF) alpha subunit = succinate + carbon dioxide + a (3S)-3-hydroxy-L-asparagine-HIF alpha subunit.	got7fsn_ti												MetaCyc:RXN-11321|RHEA:54268|EC:1.14.11.30		molecular_function											owl:Class	
GO:0009132	biolink:NamedThing	nucleoside diphosphate metabolic process	The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	nucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0051425	biolink:NamedThing	PTB domain binding	Binding to a phosphotyrosine-binding (PTB) Binding to a phosphotyrosine-bindin domain.	got7fsn_ti	PID binding|phosphotyrosine-interacting domain binding													molecular_function											owl:Class	
GO:0061027	biolink:NamedThing	umbilical cord development	The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.	got7fsn_ti							dph	2010-02-09T09:09:22Z						biological_process											owl:Class	
GO:0008866	biolink:NamedThing	fructuronate reductase activity	Catalysis of the reaction: D-mannonate + NAD(+) = D-fructuronate + H(+) + NADH.	got7fsn_ti	mannonic dehydrogenase activity|D-mannonate:NAD+ 5-oxidoreductase activity|D-mannonate oxidoreductase activity|mannonate oxidoreductase activity|D-mannonate:NAD oxidoreductase activity|D-mannonate dehydrogenase activity											MetaCyc:MANNONOXIDOREDUCT-RXN|EC:1.1.1.57|KEGG_REACTION:R02454|RHEA:15729		molecular_function											owl:Class	
GO:0047207	biolink:NamedThing	1,2-beta-fructan 1F-fructosyltransferase activity	Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1).	got7fsn_ti	2,1-beta-D-fructan:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity|1,2-beta-fructan 1(F)-fructosyltransferase activity|2,1-fructan:2,1-fructan 1-fructosyltransferase activity|1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase activity|FFT activity|1,2-beta-D-fructan 1F-fructosyltransferase activity|1,2-beta-D-fructan 1(F)-fructosyltransferase activity|fructan:fructan fructosyl transferase activity|1,2-beta-D-fructan:1,2-beta-D-fructan 1(F)-beta-D-fructosyltransferase activity											EC:2.4.1.100|MetaCyc:2.4.1.100-RXN		molecular_function											owl:Class	
GO:0098568	biolink:NamedThing	external side of mycolate outer membrane	The side (leaflet) of the mycolate outer membrane that faces the environment and any proteins embedded in it or loosely bound to its surface.	got7fsn_ti														cellular_component											owl:Class	
GO:0098927	biolink:NamedThing	vesicle-mediated transport between endosomal compartments	A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome.	got7fsn_ti														biological_process											owl:Class	
GO:0018720	biolink:NamedThing	phenol kinase activity	Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate.	got7fsn_ti												MetaCyc:PHENOLPHOS-RXN|UM-BBD_reactionID:r0155		molecular_function											owl:Class	
GO:0007537	biolink:NamedThing	inactivation of recombination (HML)	The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.	got7fsn_ti														biological_process											owl:Class	
GO:0051955	biolink:NamedThing	regulation of amino acid transport	Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0071814	biolink:NamedThing	protein-lipid complex binding	Binding to a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules.	got7fsn_ti							mah	2010-09-06T04:26:27Z						molecular_function											owl:Class	
GO:0070628	biolink:NamedThing	proteasome binding	Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation.	got7fsn_ti							mah	2009-05-01T04:38:58Z						molecular_function											owl:Class	
GO:0045451	biolink:NamedThing	pole plasm oskar mRNA localization	Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.	got7fsn_ti	establishment and maintenance of oskar mRNA localization in pole plasm|establishment and maintenance of pole plasm oskar mRNA localization|pole plasm oskar mRNA localisation|oocyte pole plasm oskar mRNA localization													biological_process											owl:Class	
GO:0019094	biolink:NamedThing	pole plasm mRNA localization	Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte pole plasm mRNA localization|pole granule RNA localization|pole plasm mRNA localisation|establishment and maintenance of mRNA localization in pole plasm|establishment and maintenance of pole plasm mRNA localization										GO:0048120			biological_process											owl:Class	
GO:0031255	biolink:NamedThing	lateral part of motile cell	The area of a motile cell perpendicular to the direction of movement.	got7fsn_ti														cellular_component											owl:Class	
GO:0050573	biolink:NamedThing	dTDP-4-dehydro-6-deoxyglucose reductase activity	Catalysis of the reaction: dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH.	got7fsn_ti	dTDP-4-keto-6-deoxyglucose reductase activity|dTDP-D-fucose:NADP+ oxidoreductase activity											MetaCyc:1.1.1.266-RXN|RHEA:36583|KEGG_REACTION:R05687|EC:1.1.1.266		molecular_function											owl:Class	
GO:0052916	biolink:NamedThing	23S rRNA (guanine(1835)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:42744|MetaCyc:RXN-11635|KEGG_REACTION:R07234|EC:2.1.1.174		molecular_function											owl:Class	
GO:0097320	biolink:NamedThing	plasma membrane tubulation	A membrane tubulation process occurring in a plasma membrane.	got7fsn_ti	membrane tubulation|vesicle scission						pr	2012-05-31T10:01:22Z						biological_process											owl:Class	
GO:0004835	biolink:NamedThing	tubulin-tyrosine ligase activity	Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate.	got7fsn_ti	alpha-tubulin:L-tyrosine ligase (ADP-forming)|tubulinyl-tyrosine ligase activity|TTL activity											RHEA:17605|EC:6.3.2.25|MetaCyc:6.3.2.25-RXN|Reactome:R-HSA-8955706		molecular_function											owl:Class	
GO:0015019	biolink:NamedThing	heparan-alpha-glucosaminide N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide.	got7fsn_ti	heparin-alpha-glucosaminide N-acetyltransferase activity|acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase activity|acetyl-CoA:alpha-glucosaminide N-acetyltransferase activity											Reactome:R-HSA-9036056|EC:2.3.1.78|Reactome:R-HSA-1678660|Reactome:R-HSA-2263492|Reactome:R-HSA-2090085|MetaCyc:2.3.1.78-RXN|RHEA:15125		molecular_function											owl:Class	
GO:0080056	biolink:NamedThing	petal vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the petal of vascular plants.	got7fsn_ti							dhl	2009-04-13T02:25:01Z						biological_process											owl:Class	
GO:1990742	biolink:NamedThing	microvesicle	An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.	got7fsn_ti	shedding vesicle|extracellular microvesicle|ectosome						pr	2015-05-13T13:44:52Z						cellular_component											owl:Class	
GO:2000706	biolink:NamedThing	negative regulation of dense core granule biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis.	got7fsn_ti							yaf	2011-05-26T10:29:27Z						biological_process											owl:Class	
GO:0102407	biolink:NamedThing	sn-2-glycerol-3-phosphate C22:0-DCA-CoA acyl transferase activity	Catalysis of the reaction: C22:0-DCA-CoA + sn-glycerol 3-phosphate <=> coenzyme A + 2-C22:0-DCA-LPA.	got7fsn_ti												MetaCyc:RXN-13734		molecular_function											owl:Class	
GO:0019255	biolink:NamedThing	glucose 1-phosphate metabolic process	The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1.	got7fsn_ti	glucose 1-phosphate utilization|glucose 1-phosphate metabolism										GO:0006008	MetaCyc:GLUCOSE1PMETAB-PWY		biological_process											owl:Class	
GO:0003914	biolink:NamedThing	DNA (6-4) photolyase activity	Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA.	got7fsn_ti												MetaCyc:RXN-10771|EC:4.1.99.13		molecular_function											owl:Class	
GO:0046816	biolink:NamedThing	virion transport vesicle	A vesicle used to transport the partial or complete virion between cellular compartments.	got7fsn_ti														cellular_component											owl:Class	
GO:0097752	biolink:NamedThing	regulation of DNA stability	Any process that modulates the stability of DNA.	got7fsn_ti							pr	2017-01-24T11:23:01Z						biological_process											owl:Class	
GO:0035365	biolink:NamedThing	regulation of thymine transport	Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of 5-methyluracil transport						bf	2010-03-11T10:22:54Z						biological_process											owl:Class	
GO:0062040	biolink:NamedThing	fungal biofilm matrix	An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.	got7fsn_ti							dph	2018-05-04T12:54:39Z						cellular_component											owl:Class	
GO:0086018	biolink:NamedThing	SA node cell to atrial cardiac muscle cell signaling	Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.	got7fsn_ti	SAN cardiomyocyte to atrial cardiomyocyte signalling|SA node cardiomyocyte to atrial cardiomyocyte signalling|sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling|SA node cardiac muscle cell to atrial cardiac muscle cell signalling|sinus node cardiomyocyte to atrial cardiomyocyte signalling						tb	2011-11-10T09:15:01Z						biological_process											owl:Class	
GO:0034655	biolink:NamedThing	nucleobase-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.	got7fsn_ti	nucleobase, nucleoside, nucleotide and nucleic acid catabolism|nucleobase, nucleoside, nucleotide and nucleic acid breakdown|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process|nucleobase, nucleoside, nucleotide and nucleic acid degradation													biological_process											owl:Class	
GO:0071703	biolink:NamedThing	detection of organic substance	The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti							mah	2010-03-08T03:18:44Z						biological_process											owl:Class	
GO:0008880	biolink:NamedThing	glucuronate isomerase activity	Catalysis of the reaction: D-glucuronate = D-fructuronate.	got7fsn_ti	uronic acid isomerase activity|D-glucuronate ketol-isomerase activity|uronic isomerase activity|D-glucuronate isomerase activity|D-glucuronate aldose-ketose-isomerase activity|uronate isomerase activity											RHEA:13049|MetaCyc:GLUCUROISOM-RXN|EC:5.3.1.12		molecular_function											owl:Class	
GO:0051835	biolink:NamedThing	positive regulation of synapse structural plasticity	Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity.	got7fsn_ti	up-regulation of synapse structural plasticity|up regulation of synapse structural plasticity|stimulation of synapse structural plasticity|upregulation of synapse structural plasticity|activation of synapse structural plasticity													biological_process											owl:Class	
GO:0001118	biolink:NamedThing	transcription ternary complex disassembly	The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components.	got7fsn_ti	transcription protein-DNA-RNA complex disassembly						krc	2010-12-03T04:11:34Z						biological_process											owl:Class	
GO:0045203	biolink:NamedThing	integral component of cell outer membrane	The component of the cell outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to external membrane|integral to cell outer membrane|integral to outer membrane													cellular_component											owl:Class	
GO:0003100	biolink:NamedThing	regulation of systemic arterial blood pressure by endothelin	The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor.	got7fsn_ti														biological_process											owl:Class	
GO:0050363	biolink:NamedThing	tryptophan dehydrogenase activity	Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+.	got7fsn_ti	L-tryptophan dehydrogenase activity|L-Trp-dehydrogenase activity|TrpDH activity|NAD(P)+-L-tryptophan dehydrogenase activity|TDH|L-tryptophan:NAD(P)+ oxidoreductase (deaminating)											EC:1.4.1.19|MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0102266	biolink:NamedThing	tRNA-dihydrouridine20a synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) <=> H+ + a uracil20a in tRNA + NAD(P)H.	got7fsn_ti												EC:1.3.1.90|MetaCyc:RXN-12475		molecular_function											owl:Class	
GO:0040022	biolink:NamedThing	feminization of hermaphroditic germ-line	The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.	got7fsn_ti														biological_process											owl:Class	
GO:0075508	biolink:NamedThing	entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm	Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm.	got7fsn_ti	entry of viral genome into host nucleus via attachment of capsid to nuclear pore complex and release of genome into nucleoplasm				This mechanism is used by viruses such as Hepadnaviridae whose capsids enter the NPC but are too big to pass intact into the nucleus.		jl	2011-07-26T04:56:10Z						biological_process											owl:Class	
GO:0007615	biolink:NamedThing	anesthesia-resistant memory	The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0080152	biolink:NamedThing	regulation of reductive pentose-phosphate cycle	Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle.	got7fsn_ti	regulation of C3 photosynthesis|regulation of Calvin cycle						dhl	2010-07-01T02:49:55Z						biological_process											owl:Class	
GO:0007367	biolink:NamedThing	segment polarity determination	Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.	got7fsn_ti														biological_process											owl:Class	
GO:0004079	biolink:NamedThing	biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase).	got7fsn_ti	biotin:apomethylmalonyl-CoA:pyruvate carboxytransferase ligase (AMP-forming)|biotin:apomethylmalonyl-CoA:pyruvate carboxyltransferase ligase (AMP-forming)|methylmalonyl coenzyme A holotranscarboxylase synthetase activity|biotin-methylmalonyl-CoA-carboxytransferase synthetase activity|biotin-[methylmalonyl-CoA-carboxyltransferase] ligase activity|biotin--[methylmalonyl-CoA-carboxyltransferase] ligase activity|biotin-methylmalonyl-CoA-carboxytransferase ligase activity|biotin--[methylmalonyl-CoA-carboxytransferase] synthetase activity|biotin-methylmalonyl-CoA-carboxyltransferase synthetase|biotin-methylmalonyl-CoA-carboxyltransferase ligase activity|biotin-methylmalonyl coenzyme A carboxyltransferase synthetase activity|biotin--[methylmalonyl-CoA-carboxyltransferase] synthetase activity|biotin-transcarboxylase synthetase activity											EC:6.3.4.9|RHEA:23668|MetaCyc:6.3.4.9-RXN		molecular_function											owl:Class	
GO:0097322	biolink:NamedThing	7SK snRNA binding	Binding to a 7SK small nuclear RNA (7SK snRNA).	got7fsn_ti	7SK small nuclear RNA binding						pr	2012-06-05T11:42:23Z						molecular_function											owl:Class	
GO:0043263	biolink:NamedThing	cellulosome	An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose.	got7fsn_ti	scaffoldin complex										GO:1990296	Wikipedia:Cellulosome		cellular_component											owl:Class	
GO:0120153	biolink:NamedThing	calcium-dependent carbohydrate binding	Binding to a carbohydrate in the presence of calcium.	got7fsn_ti							krc	2018-04-27T16:42:21Z						molecular_function											owl:Class	
GO:0030246	biolink:NamedThing	carbohydrate binding	Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.	got7fsn_ti	sugar binding|selectin										GO:0005529			molecular_function											owl:Class	
GO:0047576	biolink:NamedThing	4-chlorobenzoate dehalogenase activity	Catalysis of the reaction: 4-chlorobenzoate + H(2)O = 4-hydroxybenzoate + chloride + H(+).	got7fsn_ti	4-chlorobenzoate chlorohydrolase activity|halobenzoate dehalogenase activity											RHEA:23440|MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN|KEGG_REACTION:R01307|EC:3.8.1.6		molecular_function											owl:Class	
GO:0150058	biolink:NamedThing	amylin receptor complex 3	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signalling pathways.	got7fsn_ti	AMY3 complex						bc	2018-06-21T10:54:00Z						cellular_component											owl:Class	
GO:0014871	biolink:NamedThing	cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction	The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0070390	biolink:NamedThing	transcription export complex 2	A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.	got7fsn_ti	TREX-2 complex|Sac3-Thp1-Sus1-Sem1-Cdc31 complex													cellular_component											owl:Class	
GO:0102439	biolink:NamedThing	3',4',5'-trimethylmyricetin 7-O-methyltransferase activity	Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine  <=> 7,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-13916		molecular_function											owl:Class	
GO:0015090	biolink:NamedThing	low-affinity ferric iron ion transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low affinity iron transporter activity|low affinity iron ion transmembrane transporter activity													molecular_function											owl:Class	
GO:0102763	biolink:NamedThing	phytyl-P kinase activity	Catalysis of the reaction: phytyl phosphate(2-) + a nucleoside triphosphate <=> (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + a nucleoside diphosphate.	got7fsn_ti												RHEA:38099|MetaCyc:RXN-7763		molecular_function											owl:Class	
GO:0010086	biolink:NamedThing	embryonic root morphogenesis	The process in which the anatomical structures of the embryonic root are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0060365	biolink:NamedThing	coronal suture morphogenesis	The process in which the coronal suture is generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0008839	biolink:NamedThing	4-hydroxy-tetrahydrodipicolinate reductase	Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+.	got7fsn_ti	dihydrodipicolinate reductase activity|dihydrodipicolinic acid reductase activity|2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity											EC:1.17.1.8|MetaCyc:DIHYDROPICRED-RXN		molecular_function											owl:Class	
GO:0042610	biolink:NamedThing	CD8 receptor binding	Binding to a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes.	got7fsn_ti														molecular_function											owl:Class	
GO:0061671	biolink:NamedThing	Cbp3p-Cbp6 complex	A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly.	got7fsn_ti							dph	2014-11-18T15:08:30Z						cellular_component											owl:Class	
GO:0004828	biolink:NamedThing	serine-tRNA ligase activity	Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).	got7fsn_ti	seryl-transfer RNA synthetase activity|seryl-tRNA synthetase activity|serine translase activity|seryl-transfer ribonucleic acid synthetase activity|L-serine:tRNASer ligase (AMP-forming)|SerRS activity|seryl-transfer ribonucleate synthetase activity											Reactome:R-HSA-379992|Reactome:R-HSA-380239|RHEA:12292|EC:6.1.1.11|MetaCyc:SERINE--TRNA-LIGASE-RXN		molecular_function											owl:Class	
GO:0050281	biolink:NamedThing	serine-glyoxylate transaminase activity	Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine.	got7fsn_ti	SGAT activity|serine--glyoxylate aminotransferase activity|L-serine:glyoxylate aminotransferase activity											MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN|RHEA:19125|EC:2.6.1.45		molecular_function											owl:Class	
GO:0004024	biolink:NamedThing	alcohol dehydrogenase activity, zinc-dependent	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.	got7fsn_ti												Reactome:R-HSA-71707		molecular_function											owl:Class	
GO:0008466	biolink:NamedThing	glycogenin glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin.	got7fsn_ti	glycogenin activity|alpha-1,4-glucan-protein synthase (UDP-forming) activity|UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase activity|priming glucosyltransferase activity|UDP-glucose:glycogenin glucosyltransferase activity|1,4alpha-glucan-protein synthase (UDP-forming) activity										GO:0047210	Reactome:R-HSA-3814838|RHEA:23360|Reactome:R-HSA-3322014|MetaCyc:GLYCOGENIN-GLUCOSYLTRANSFERASE-RXN|Reactome:R-HSA-3322019|Reactome:R-HSA-3322025|EC:2.4.1.186|Reactome:R-HSA-3322003		molecular_function											owl:Class	
GO:0008860	biolink:NamedThing	ferredoxin-NAD+ reductase activity	Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+.	got7fsn_ti	ferredoxin-nicotinamide adenine dinucleotide reductase activity|ferredoxin:NAD+ oxidoreductase activity|NADH flavodoxin oxidoreductase activity|NADH-ferredoxinTOL reductase (component of toluene dioxygenase)|NADH-ferredoxin oxidoreductase activity|ferredoxin-NAD reductase activity|NAD-ferredoxin reductase activity|NADH-ferredoxin reductase activity|NADH2-ferredoxin oxidoreductase activity|reductase, reduced nicotinamide adenine dinucleotide-ferredoxin|NADH-ferredoxinNAP reductase (component of naphthalene dioxygenase multicomponent enzyme system)|ferredoxin-linked NAD reductase activity											MetaCyc:FERREDOXIN--NAD+-REDUCTASE-RXN|RHEA:16521|EC:1.18.1.3		molecular_function											owl:Class	
GO:0102954	biolink:NamedThing	dalcochinase activity	Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O <=> dalcochinin + D-glucopyranose.	got7fsn_ti												MetaCyc:RXN-9162		molecular_function											owl:Class	
GO:0036106	biolink:NamedThing	peroxisome membrane class-2 targeting sequence binding	Binding to a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner.	got7fsn_ti	class 2 mPTS binding|PEX19-independent mPTS binding				Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence.		bf	2012-01-27T02:02:22Z						molecular_function											owl:Class	
GO:0008820	biolink:NamedThing	cobinamide phosphate guanylyltransferase activity	Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate.	got7fsn_ti	CobU|adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase|GTP:cobinamide phosphate guanylyltransferase activity|GTP:adenosylcobinamide-phosphate guanylyltransferase activity|AdoCbi kinase/AdoCbi-phosphate guanylyltransferase|adenosylcobinamide-phosphate guanylyltransferase activity										GO:0043753	RHEA:22712|KEGG_REACTION:R05222|EC:2.7.7.62|MetaCyc:COBINPGUANYLYLTRANS-RXN		molecular_function											owl:Class	
GO:0047691	biolink:NamedThing	aspulvinone dimethylallyltransferase activity	Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate.	got7fsn_ti	dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase activity|dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase activity											EC:2.5.1.35|MetaCyc:ASPULVINONE-DIMETHYLALLYLTRANSFERASE-RXN|KEGG_REACTION:R03799|RHEA:13809		molecular_function											owl:Class	
GO:0047895	biolink:NamedThing	formaldehyde dismutase activity	Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.	got7fsn_ti	aldehyde dismutase activity|cannizzanase activity|nicotinoprotein aldehyde dismutase|formaldehyde:formaldehyde oxidoreductase activity											RHEA:19221|MetaCyc:FORMALDEHYDE-DISMUTASE-RXN|EC:1.2.98.1		molecular_function											owl:Class	
GO:0106235	biolink:NamedThing	ceramide-1-phosphate phosphatase activity	Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate.	got7fsn_ti							hjd	2019-11-21T20:40:39Z				RHEA:50888		molecular_function											owl:Class	
GO:0042577	biolink:NamedThing	lipid phosphatase activity	Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0048465	biolink:NamedThing	corolla development	The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0048335	biolink:NamedThing	negative regulation of mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.	got7fsn_ti	down regulation of mesodermal cell fate determination|inhibition of mesodermal cell fate determination|down-regulation of mesodermal cell fate determination|downregulation of mesodermal cell fate determination													biological_process											owl:Class	
GO:0043335	biolink:NamedThing	protein unfolding	The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state.	got7fsn_ti														biological_process											owl:Class	
GO:0050642	biolink:NamedThing	2-alpha-hydroxytaxane 2-O-benzoyltransferase activity	Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA.	got7fsn_ti	2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase activity|benzoyl-CoA:taxane 2alpha-O-benzoyltransferase activity|2alpha-hydroxytaxane 2-O-benzoyltransferase activity|benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase activity|2a-hydroxytaxane 2-O-benzoyltransferase activity|benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase activity											RHEA:18741|EC:2.3.1.166|MetaCyc:2.3.1.166-RXN|KEGG_REACTION:R06310		molecular_function											owl:Class	
GO:1902108	biolink:NamedThing	regulation of mitochondrial membrane permeability involved in apoptotic process	Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.	got7fsn_ti	regulation of mitochondrial membrane permeability involved in apoptotic program|regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|regulation of mitochondrial membrane permeability involved in type I programmed cell death|regulation of transport across mitochondrial membrane involved in apoptotic cell death|regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|regulation of transport across mitochondrial membrane involved in type I programmed cell death|regulation of mitochondrial membrane permeability involved in apoptotic cell death|regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|regulation of transport across mitochondrial membrane involved in apoptotic process|regulation of transport across mitochondrial membrane involved in apoptotic program|regulation of mitochondrial membrane permeability involved in apoptosis|regulation of transport across mitochondrial membrane involved in apoptosis|regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis						pr	2013-05-03T12:09:35Z						biological_process											owl:Class	
GO:0004222	biolink:NamedThing	metalloendopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	got7fsn_ti	metalloendoproteinase activity|metalloendoprotease activity											Reactome:R-HSA-8874187|MetaCyc:3.4.24.61-RXN|MetaCyc:3.4.24.21-RXN|Reactome:R-HSA-1251992|Reactome:R-HSA-1474210|Reactome:R-HSA-8940641|Reactome:R-HSA-381518|MetaCyc:3.4.24.35-RXN|EC:3.4.24.18|Reactome:R-HSA-264758|MetaCyc:3.4.24.17-RXN|Reactome:R-HSA-5250606|MetaCyc:3.4.24.24-RXN|EC:3.4.24.22|EC:3.4.24.11|Reactome:R-HSA-2533965|Reactome:R-HSA-8949668|MetaCyc:3.4.24.57-RXN|Reactome:R-HSA-8874194|MetaCyc:3.4.24.56-RXN|Reactome:R-HSA-2534240|Reactome:R-HSA-8876868|EC:3.4.24.61|Reactome:R-HSA-1299476|MetaCyc:3.4.24.69-RXN|Reactome:R-HSA-1564164|Reactome:R-HSA-1564112|Reactome:R-HSA-194800|Reactome:R-HSA-2179402|Reactome:R-HSA-3788075|MetaCyc:3.4.24.23-RXN|EC:3.4.24.72|MetaCyc:3.4.24.55-RXN|Reactome:R-HSA-2533950|Reactome:R-HSA-381537|MetaCyc:3.4.24.71-RXN|Reactome:R-HSA-1564179|Reactome:R-HSA-2485111|EC:3.4.24.37|Reactome:R-HSA-177946|Reactome:R-HSA-420818|Reactome:R-HSA-1564184|Reactome:R-HSA-4224014|Reactome:R-HSA-1474213|MetaCyc:3.4.24.18-RXN|Reactome:R-HSA-2514831|Reactome:R-HSA-8940561|EC:3.4.24.57|Reactome:R-HSA-9624272|Reactome:R-HSA-2473594|EC:3.4.24.14|Reactome:R-HSA-3827958|MetaCyc:3.4.24.37-RXN|EC:3.4.24.59|Reactome:R-HSA-2534248|Reactome:R-HSA-1168777|EC:3.4.24.-|Reactome:R-HSA-1564143|Reactome:R-HSA-3791295|Reactome:R-HSA-1564142|Reactome:R-HSA-2002428|Reactome:R-HSA-5694082|Reactome:R-HSA-8874195|Reactome:R-HSA-1592310|Reactome:R-HSA-181567|Reactome:R-HSA-3791149|Reactome:R-HSA-8949649|Reactome:R-HSA-2473596|Reactome:R-HSA-8940959|EC:3.4.24.23|Reactome:R-HSA-3791319|Reactome:R-HSA-5333671|EC:3.4.24.19|Reactome:R-HSA-1474196|Reactome:R-HSA-5362793|Reactome:R-HSA-3791155|Reactome:R-HSA-1299478|Reactome:R-HSA-2485148|MetaCyc:3.4.24.64-RXN|Reactome:R-HSA-8874192|Reactome:R-HSA-194809|MetaCyc:3.4.24.22-RXN|EC:3.4.24.56|EC:3.4.24.17|Reactome:R-HSA-5250978|EC:3.4.24.69|Reactome:R-HSA-8940554|Reactome:R-HSA-2514790|MetaCyc:3.4.24.59-RXN|Reactome:R-HSA-6784620|Reactome:R-HSA-5228578|MetaCyc:3.4.24.14-RXN|EC:3.4.24.35|Reactome:R-HSA-1454822|EC:3.4.24.70|Reactome:R-HSA-8942302|Reactome:R-HSA-2533970|Reactome:R-HSA-194796|Reactome:R-HSA-3828025|Reactome:R-HSA-2168046|Reactome:R-HSA-1655851|EC:3.4.24.64|Reactome:R-HSA-4086205|Reactome:R-HSA-2002440|Reactome:R-HSA-381435|Reactome:R-HSA-1454757|Reactome:R-HSA-3371385|Reactome:R-HSA-2473584|Reactome:R-HSA-8877620|MetaCyc:3.4.24.70-RXN|Reactome:R-HSA-2533874|Reactome:R-HSA-194793|Reactome:R-HSA-1564120|Reactome:R-HSA-5250962|Reactome:R-HSA-8874201|Reactome:R-HSA-8867344|Reactome:R-HSA-8949659|EC:3.4.24.55|Reactome:R-HSA-1564117|Reactome:R-HSA-194818|MetaCyc:3.4.24.19-RXN|EC:3.4.24.24|Reactome:R-HSA-2533944|MetaCyc:3.4.24.72-RXN|Reactome:R-HSA-2022141|Reactome:R-HSA-194808|Reactome:R-HSA-8943959|Reactome:R-HSA-2537499|EC:3.4.24.71|MetaCyc:3.4.24.11-RXN|Reactome:R-HSA-1564169|Reactome:R-HSA-1458433|EC:3.4.24.21|Reactome:R-HSA-2484882|Reactome:R-HSA-2168982|Reactome:R-HSA-5250892		molecular_function											owl:Class	
GO:0080065	biolink:NamedThing	4-alpha-methyl-delta7-sterol oxidation	A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O.	got7fsn_ti	4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase activity						dhl	2009-04-13T03:41:50Z						biological_process											owl:Class	
GO:0097077	biolink:NamedThing	copper ion sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+).	got7fsn_ti							pr	2011-06-17T09:57:11Z						molecular_function											owl:Class	
GO:0015327	biolink:NamedThing	cystine:glutamate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out).	got7fsn_ti														molecular_function											owl:Class	
GO:0034915	biolink:NamedThing	2-methylhexanoyl-CoA C-acetyltransferase activity	Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA.	got7fsn_ti												EC:2.3.1.-|UM-BBD_reactionID:r0927		molecular_function											owl:Class	
GO:0005500	biolink:NamedThing	juvenile hormone binding	Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	got7fsn_ti														molecular_function											owl:Class	
GO:0048643	biolink:NamedThing	positive regulation of skeletal muscle tissue development	Any process that activates, maintains or increases the rate of skeletal muscle tissue development.	got7fsn_ti	upregulation of skeletal muscle development|activation of skeletal muscle development|stimulation of skeletal muscle development|up regulation of skeletal muscle development|up-regulation of skeletal muscle development													biological_process											owl:Class	
GO:0090400	biolink:NamedThing	stress-induced premature senescence	A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays.	got7fsn_ti	SIPS						tb	2011-01-05T02:32:29Z						biological_process											owl:Class	
GO:1903982	biolink:NamedThing	negative regulation of microvillus length	A process that decreases the length of a microvillus.	got7fsn_ti	down regulation of regulation of microvillus length|downregulation of regulation of microvillus length|down-regulation of regulation of microvillus length|inhibition of regulation of microvillus length						als	2015-03-03T13:23:52Z						biological_process											owl:Class	
GO:0031345	biolink:NamedThing	negative regulation of cell projection organization	Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.	got7fsn_ti	negative regulation of cell projection organization and biogenesis|inhibition of cell projection organization|down-regulation of cell projection organization|negative regulation of cell projection organisation|down regulation of cell projection organization|downregulation of cell projection organization													biological_process											owl:Class	
GO:0030083	biolink:NamedThing	PSI associated light-harvesting complex I, LHCIa subcomplex	A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm.	got7fsn_ti														cellular_component											owl:Class	
GO:0009518	biolink:NamedThing	PSI associated light-harvesting complex I	Protein-pigment complex associated with photosystem I.	got7fsn_ti	LHCI													cellular_component											owl:Class	
GO:0033208	biolink:NamedThing	UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide.	got7fsn_ti	Sda beta 1,4GalNAc transferase|UDP-GalNAc:Neu5Ac-alpha-2-Gal-beta-1-R beta-1,4-N-acetylgalactosaminyltransferase activity													molecular_function											owl:Class	
GO:0033398	biolink:NamedThing	zeatin biosynthetic process	The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	got7fsn_ti	zeatin synthesis|zeatin biosynthesis|zeatin formation|zeatin anabolism													biological_process											owl:Class	
GO:0031619	biolink:NamedThing	homologous chromosome orientation involved in meiotic metaphase I plate congression	The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I.	got7fsn_ti	homologous chromosome orientation during meiosis I|homologous chromosome orientation during meiosis													biological_process											owl:Class	
GO:0002173	biolink:NamedThing	low-affinity IgM receptor activity	Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	low affinity IgM receptor activity						hjd	2010-05-06T05:04:24Z						molecular_function											owl:Class	
GO:0051112	biolink:NamedThing	peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine	The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).	got7fsn_ti												RESID:AA0371		biological_process											owl:Class	
GO:0061547	biolink:NamedThing	glycogen synthase activity, transferring glucose-1-phosphate	Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.	got7fsn_ti							dph	2013-07-02T09:59:18Z				Reactome:R-HSA-3781024|Reactome:R-HSA-3780994		molecular_function											owl:Class	
GO:0047033	biolink:NamedThing	15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H(+) + NADPH.	got7fsn_ti	PG I2 dehydrogenase activity|NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity|prostacyclin dehydrogenase activity|(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity|NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity											KEGG_REACTION:R03520|RHEA:21420|EC:1.1.1.231|MetaCyc:1.1.1.231-RXN		molecular_function											owl:Class	
GO:0010450	biolink:NamedThing	inflorescence meristem growth	The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers.	got7fsn_ti														biological_process											owl:Class	
GO:0008504	biolink:NamedThing	monoamine transmembrane transporter activity	Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.	got7fsn_ti											GO:0015201	Reactome:R-HSA-5660706|Reactome:R-HSA-380586|Reactome:R-HSA-379393|Reactome:R-HSA-380620|Reactome:R-HSA-444160|Reactome:R-HSA-372542		molecular_function											owl:Class	
GO:0061632	biolink:NamedThing	RNA lariat debranching enzyme activator activity	Increases the activity of an enzyme that catalyzes the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.	got7fsn_ti							dph	2014-06-17T10:07:31Z						molecular_function											owl:Class	
GO:0050545	biolink:NamedThing	sulfopyruvate decarboxylase activity	Catalysis of the reaction: 3-sulfopyruvate + H(+) = CO(2) + sulfoacetaldehyde.	got7fsn_ti	sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming)|sulfopyruvate carboxy-lyase activity|sulphopyruvate decarboxylase activity											RHEA:20948|EC:4.1.1.79|KEGG_REACTION:R05774|MetaCyc:R231-RXN		molecular_function											owl:Class	
GO:0008832	biolink:NamedThing	dGTPase activity	Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate.	got7fsn_ti	deoxy-GTPase activity|deoxyguanosinetriphosphate triphosphohydrolase activity|dGTP triphosphohydrolase activity|deoxyguanosine triphosphatase activity|deoxyguanosine 5-triphosphate triphosphohydrolase activity|deoxyguanosine triphosphate triphosphohydrolase activity											EC:3.1.5.1|MetaCyc:DGTPTRIPHYDRO-RXN|RHEA:15193|KEGG_REACTION:R01856		molecular_function											owl:Class	
GO:0102922	biolink:NamedThing	phenylpropanoyltransferase activity	Catalysis of the reaction: baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = N-debenzoyl-(3'-RS)-2'-deoxytaxol + coenzyme A.	got7fsn_ti												MetaCyc:RXN-8857|RHEA:42488		molecular_function											owl:Class	
GO:0002319	biolink:NamedThing	memory B cell differentiation	The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.	got7fsn_ti	memory B-lymphocyte differentiation|memory B lymphocyte differentiation|memory B-cell differentiation|memory B cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0032305	biolink:NamedThing	positive regulation of icosanoid secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.	got7fsn_ti	stimulation of icosanoid secretion|up-regulation of icosanoid secretion|positive regulation of eicosanoid secretion|activation of icosanoid secretion|up regulation of icosanoid secretion|upregulation of icosanoid secretion													biological_process											owl:Class	
GO:2000193	biolink:NamedThing	positive regulation of fatty acid transport	Any process that activates or increases the frequency, rate or extent of fatty acid transport.	got7fsn_ti							rl	2010-10-18T10:37:17Z						biological_process											owl:Class	
GO:0008852	biolink:NamedThing	exodeoxyribonuclease I activity	Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides.	got7fsn_ti	E. coli exonuclease I|Escherichia coli exonuclease I|exonuclease I activity|E. coli exonuclease I activity											MetaCyc:3.1.11.1-RXN|EC:3.1.11.1		molecular_function											owl:Class	
GO:0061381	biolink:NamedThing	cell migration in diencephalon	The orderly movement of a cell that will reside in the diencephalon.	got7fsn_ti							dph	2010-11-09T09:54:27Z						biological_process											owl:Class	
GO:0017134	biolink:NamedThing	fibroblast growth factor binding	Binding to a fibroblast growth factor.	got7fsn_ti	fibroblast growth factor 6 binding|fibroblast growth factor 5 binding|FGF 4 binding|fibroblast growth factor 3 binding|FGF 3 binding|FGF 2 binding|FGF 5 binding|fibroblast growth factor 2 binding|FGF binding|FGF 1 binding|fibroblast growth factor 1 binding|FGF 6 binding|fibroblast growth factor 4 binding										GO:0048606|GO:0048602|GO:0048607|GO:0048605|GO:0048604|GO:0048603			molecular_function											owl:Class	
GO:0042981	biolink:NamedThing	regulation of apoptotic process	Any process that modulates the occurrence or rate of cell death by apoptotic process.	got7fsn_ti	apoptosis regulator activity|regulation of apoptosis				This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.									biological_process											owl:Class	
GO:0016994	biolink:NamedThing	precorrin-6A reductase activity	Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+.	got7fsn_ti	precorrin-6Y:NADP+ oxidoreductase activity|precorrin-6Y:NADP(+) oxidoreductase activity|precorrin-6X reductase activity|precorrin-6B:NADP+ oxidoreductase activity											EC:1.3.1.54|RHEA:23408|MetaCyc:1.3.1.54-RXN		molecular_function											owl:Class	
GO:0090118	biolink:NamedThing	receptor-mediated endocytosis involved in cholesterol transport	A receptor-mediated endocytosis process involved in intracellular cholesterol transport.	got7fsn_ti	receptor-mediated endocytosis of LDL|receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|receptor-mediated endocytosis involved in intracellular cholesterol transport						tb	2009-12-07T12:06:05Z						biological_process											owl:Class	
GO:0097168	biolink:NamedThing	mesenchymal stem cell proliferation	The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	got7fsn_ti	MSC proliferation						pr	2011-09-29T04:44:48Z						biological_process											owl:Class	
GO:0032410	biolink:NamedThing	negative regulation of transporter activity	Any process that stops or reduces the activity of a transporter.	got7fsn_ti	down regulation of transporter activity|downregulation of transporter activity|inhibition of transporter activity|down-regulation of transporter activity													biological_process											owl:Class	
GO:0004720	biolink:NamedThing	protein-lysine 6-oxidase activity	Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide.	got7fsn_ti	protein-L-lysine:oxygen 6-oxidoreductase (deaminating)|lysyl oxidase activity										GO:0018056	EC:1.4.3.13|Reactome:R-HSA-2002466|MetaCyc:PROTEIN-LYSINE-6-OXIDASE-RXN|Reactome:R-HSA-2395340|RHEA:24544|Reactome:R-HSA-2129375		molecular_function											owl:Class	
GO:0102056	biolink:NamedThing	11-hydroxyjasmonate sulfotransferase activity	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + an 11-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + H+ + an 11-hydroxyjasmonate sulfate.	got7fsn_ti												RHEA:52732|MetaCyc:RXN-10453|EC:2.8.2.39		molecular_function											owl:Class	
GO:0008963	biolink:NamedThing	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol.	got7fsn_ti	MraY transferase activity|UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol transferase activity|phospho-MurNAc-pentapeptide transferase activity|UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity|phosphoacetylmuramoylpentapeptide translocase activity|phospho-NAc-muramoyl-pentapeptide translocase (UMP) activity|UDP-MurNAc-pentapeptide phosphotransferase activity|UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C55-isoprenoid alcohol transferase activity|UDP-MurAc(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase activity|UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity|phospho-N-acetylmuramoyl pentapeptide translocase activity|phosphoacetylmuramoylpentapeptidetransferase activity				Note that EC classifies all three 'UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity ; GO:0051992' and 'phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963' under EC:2.7.8.13.							MetaCyc:RXN-8975|EC:2.7.8.13|RHEA:21920		molecular_function											owl:Class	
GO:0008868	biolink:NamedThing	galactitol-1-phosphate 5-dehydrogenase activity	Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+.	got7fsn_ti	galactitol-1-phosphate:NAD+ oxidoreductase activity											EC:1.1.1.251|MetaCyc:1.1.1.251-RXN|RHEA:15137		molecular_function											owl:Class	
GO:0060264	biolink:NamedThing	regulation of respiratory burst involved in inflammatory response	Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	got7fsn_ti	regulation of respiratory burst involved in acute inflammatory response													biological_process											owl:Class	
GO:0045088	biolink:NamedThing	regulation of innate immune response	Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.	got7fsn_ti														biological_process											owl:Class	
GO:0010041	biolink:NamedThing	response to iron(III) ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.	got7fsn_ti	response to iron(III)													biological_process											owl:Class	
GO:0003409	biolink:NamedThing	optic cup structural organization	The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure.	got7fsn_ti	optic cup structural organisation						dph	2009-12-21T02:44:20Z						biological_process											owl:Class	
GO:0016710	biolink:NamedThing	trans-cinnamate 4-monooxygenase activity	Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O.	got7fsn_ti	hydroxylase, cinnamate 4-|cinnamic acid p-hydroxylase activity|cinnamate hydroxylase activity|cinnamate 4-monooxygenase activity|cinnamic 4-hydroxylase activity|t-cinnamic acid hydroxylase activity|CA4H activity|cinnamic acid 4-hydroxylase activity|oxygenase, cinnamate 4-mono-|cinnamate 4-hydroxylase activity|trans-cinnamate,NADPH:oxygen oxidoreductase (4-hydroxylating)|trans-cinnamic acid 4-hydroxylase activity|trans-cinnamate 4-hydroxylase activity|cytochrome P450 cinnamate 4-hydroxylase activity|cinnamic acid 4-monooxygenase activity											MetaCyc:TRANS-CINNAMATE-4-MONOOXYGENASE-RXN|EC:1.14.14.91|RHEA:10608		molecular_function											owl:Class	
GO:0060238	biolink:NamedThing	regulation of signal transduction involved in conjugation with cellular fusion	Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0003870	biolink:NamedThing	5-aminolevulinate synthase activity	Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA.	got7fsn_ti	succinyl-CoA:glycine C-succinyltransferase (decarboxylating)|delta-aminolevulinic synthetase activity|delta-aminolevulinate synthase activity|delta-ALA synthetase activity|delta-aminolevulinic acid synthetase activity|alpha-aminolevulinic acid synthase activity|aminolevulinate synthase activity|aminolevulinate synthetase activity|ALA synthetase activity|aminolevulinic acid synthetase activity|5-aminolevulinic acid synthetase activity|delta-aminolevulinic acid synthase activity|aminolevulinic synthetase activity|ALA synthase activity|ALAS activity|delta-aminolevulinate synthetase activity|5-aminolevulinate synthetase activity|aminolevulinic acid synthase activity|5-aminolevulinic acid synthase activity											EC:2.3.1.37|Reactome:R-HSA-189442|RHEA:12921|KEGG_REACTION:R00830|MetaCyc:5-AMINOLEVULINIC-ACID-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0031225	biolink:NamedThing	anchored component of membrane	The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti	anchored to membrane													cellular_component											owl:Class	
GO:0036299	biolink:NamedThing	non-recombinational interstrand cross-link repair	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination.	got7fsn_ti	recombination-independent interstrand cross-link repair|recombination-independent ICL repair						bf	2012-08-07T11:11:59Z						biological_process											owl:Class	
GO:0090712	biolink:NamedThing	basal pole of outer hair cell	The end of the outer hair cell which receives and transmits neural signals.	got7fsn_ti							tb	2016-11-01T12:57:03Z						cellular_component											owl:Class	
GO:0044074	biolink:NamedThing	negative regulation by symbiont of host translation	The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism.	got7fsn_ti	negative regulation of host translation by symbiont													biological_process											owl:Class	
GO:0044073	biolink:NamedThing	modulation by symbiont of host translation	The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism.	got7fsn_ti	modification by symbiont of host translation|modulation of host translation by symbiont|regulation by symbiont of host translation													biological_process											owl:Class	
GO:0008779	biolink:NamedThing	acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine.	got7fsn_ti	acyl-[acyl-carrier protein]-phospholipid O-acyltransferase activity|acyl-acyl-carrier-protein-phospholipid O-acyltransferase activity|acyl-ACP-phospholipid O-acyltransferase activity|acyl-acyl-carrier-protein:O-(2-acyl-sn-glycero-3-phospho)-ethanolamine O-acyltransferase activity											RHEA:10304|MetaCyc:ACYLGPEACYLTRANS-RXN|EC:2.3.1.40		molecular_function											owl:Class	
GO:0030838	biolink:NamedThing	positive regulation of actin filament polymerization	Any process that activates or increases the frequency, rate or extent of actin polymerization.	got7fsn_ti	stimulation of actin filament polymerization|up-regulation of actin filament polymerization|positive regulation of actin polymerization and/or depolymerization|positive regulation of actin polymerization|up regulation of actin filament polymerization|upregulation of actin filament polymerization|activation of actin filament polymerization				Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin depolymerization ; GO:0030836').									biological_process											owl:Class	
GO:0099096	biolink:NamedThing	vestibular calyx terminal	The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0051083	biolink:NamedThing	'de novo' cotranslational protein folding	The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.	got7fsn_ti	multidomain protein assembly|nascent polypeptide association|'de novo' co-translational protein folding										GO:0006444			biological_process											owl:Class	
GO:0052756	biolink:NamedThing	chitobiose phosphorylase activity	Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units.	got7fsn_ti							ai	2011-09-27T04:04:53Z						molecular_function											owl:Class	
GO:0006534	biolink:NamedThing	cysteine metabolic process	The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.	got7fsn_ti	cysteine metabolism											Wikipedia:Cysteine_metabolism		biological_process											owl:Class	
GO:0018567	biolink:NamedThing	styrene dioxygenase activity	Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0256		molecular_function											owl:Class	
GO:2000944	biolink:NamedThing	positive regulation of amylopectin metabolic process	Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process.	got7fsn_ti	positive regulation of Amylopectin metabolism						tt	2011-08-01T02:10:36Z						biological_process											owl:Class	
GO:0032990	biolink:NamedThing	cell part morphogenesis	The process in which the anatomical structures of a cell part are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0047695	biolink:NamedThing	benzoin aldolase activity	Catalysis of the reaction: benzoin = 2 benzaldehyde.	got7fsn_ti	benzaldehyde lyase activity|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2- activity|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase activity|diphenylethanone benzaldehyde-lyase activity|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)											RHEA:21460|MetaCyc:BENZOIN-ALDOLASE-RXN|EC:4.1.2.38|KEGG_REACTION:R00027		molecular_function											owl:Class	
GO:0061270	biolink:NamedThing	mesonephric intraglomerular mesangial cell proliferation	The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.	got7fsn_ti							dph	2010-08-30T03:23:10Z						biological_process											owl:Class	
GO:0098786	biolink:NamedThing	biofilm matrix disassembly	A process that results in the disassembly of a biofilm matrix.	got7fsn_ti														biological_process											owl:Class	
GO:0039717	biolink:NamedThing	spherule viral factory	A cytoplasmic viral factory which is a 50-400nm diameter membrane invagination. Spherules can appear on several enveloped cellular components depending on the virus.	got7fsn_ti							bf	2013-12-19T15:25:57Z				Wikipedia:Viroplasm		cellular_component											owl:Class	
GO:0102232	biolink:NamedThing	acrolein reductase activity	Catalysis of the reaction: acrolein + NADPH + H+ <=> propanal + NADP.	got7fsn_ti												MetaCyc:RXN-12281		molecular_function											owl:Class	
GO:0033910	biolink:NamedThing	glucan 1,4-alpha-maltotetraohydrolase activity	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.	got7fsn_ti	maltotetraose-forming amylase activity|G4-amylase activity|exo-maltotetraohydrolase activity|glucan 1,4-alpha-maltotetrahydrolase activity|1,4-alpha-D-glucan maltotetraohydrolase activity											EC:3.2.1.60|MetaCyc:3.2.1.60-RXN		molecular_function											owl:Class	
GO:0035509	biolink:NamedThing	negative regulation of myosin-light-chain-phosphatase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity.	got7fsn_ti							bf	2010-04-30T10:56:34Z						biological_process											owl:Class	
GO:0016162	biolink:NamedThing	cellulose 1,4-beta-cellobiosidase activity	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.	got7fsn_ti	beta-1,4-glucan cellobiohydrolase activity|exoglucanase activity|avicelase activity|1,4-beta-D-glucan cellobiohydrolase activity|cellobiohydrolase activity|CBH 1|cellobiosidase activity|cellobiohydrolase I|1,4-beta-glucan cellobiosidase activity|C1 cellulase activity|exo-1,4-beta-D-glucanase activity|exocellobiohydrolase activity|exo-cellobiohydrolase activity|exo-beta-1,4-glucan cellobiohydrolase activity|1,4-beta-cellobiohydrolase activity|beta-1,4-glucan cellobiosylhydrolase activity											MetaCyc:3.2.1.91-RXN|EC:3.2.1.91		molecular_function											owl:Class	
GO:0090551	biolink:NamedThing	response to manganese starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese.	got7fsn_ti							tb	2013-04-22T13:57:16Z						biological_process											owl:Class	
GO:0140066	biolink:NamedThing	peptidyl-lysine crotonylation	The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid.	got7fsn_ti							pg	2017-07-20T16:48:58Z						biological_process											owl:Class	
GO:0032190	biolink:NamedThing	acrosin binding	Binding to acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.	got7fsn_ti	acrosin heavy chain binding|acrosin light chain binding										GO:0032192|GO:0032191			molecular_function											owl:Class	
GO:0031732	biolink:NamedThing	CCR7 chemokine receptor binding	Binding to a CCR7 chemokine receptor.	got7fsn_ti	type 1 EBV-induced G-protein coupled receptor binding|MIP-3 beta receptor binding|CCR7 chemokine receptor ligand													molecular_function											owl:Class	
GO:0071267	biolink:NamedThing	L-methionine salvage	Any process that generates L-methionine from derivatives of it, without de novo synthesis.	got7fsn_ti							mah	2009-12-09T04:36:49Z						biological_process											owl:Class	
GO:0060838	biolink:NamedThing	lymphatic endothelial cell fate commitment	The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell.	got7fsn_ti							dph	2009-08-11T03:51:45Z						biological_process											owl:Class	
GO:0016984	biolink:NamedThing	ribulose-bisphosphate carboxylase activity	Catalysis of the reaction: 2 (2R)-3-phosphoglycerate + 2 H+ = CO2 + D-ribulose 1,5-bisphosphate + H2O.	got7fsn_ti	ribulose diphosphate carboxylase activity|ribulose 1,5-bisphosphate carboxylase activity|diphosphoribulose carboxylase activity|ribulose 1,5-diphosphate carboxylase activity|carboxydismutase activity|rubisco activity|D-ribulose 1,5-diphosphate carboxylase activity|ribulose diphosphate carboxylase/oxygenase activity|RuBP carboxylase activity|RuBisCO activity|ribulose 1,5-diphosphate carboxylase/oxygenase activity|D-ribulose-1,5-bisphosphate carboxylase activity|ribulose bisphosphate carboxylase/oxygenase activity|ribulose 1,5-bisphosphate carboxylase/oxygenase activity											MetaCyc:RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN|RHEA:23124|EC:4.1.1.39		molecular_function											owl:Class	
GO:0102998	biolink:NamedThing	4-sulfomuconolactone hydrolase activity	Catalysis of the reaction: (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate + H2O <=> maleylacetate + sulfite + 2 H+.	got7fsn_ti												RHEA:33711|EC:3.1.1.92|MetaCyc:RXN-9733		molecular_function											owl:Class	
GO:0050143	biolink:NamedThing	nocardicin-A epimerase activity	Catalysis of the reaction: isonocardicin A = nocardicin A.	got7fsn_ti	isonocardicin A epimerase activity											RHEA:22792|KEGG_REACTION:R03073|EC:5.1.1.14|MetaCyc:NOCARDICIN-A-EPIMERASE-RXN		molecular_function											owl:Class	
GO:1990063	biolink:NamedThing	Bam protein complex	Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex.	got7fsn_ti	OMP complex						bhm	2013-03-20T15:42:57Z						cellular_component											owl:Class	
GO:0004488	biolink:NamedThing	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH.	got7fsn_ti	5,10-methylenetetrahydrofolate:NADP+ oxidoreductase activity|5,10-methylenetetrahydrofolate:NADP oxidoreductase activity											RHEA:22812|EC:1.5.1.5|MetaCyc:METHYLENETHFDEHYDROG-NADP-RXN|KEGG_REACTION:R01220		molecular_function											owl:Class	
GO:0033827	biolink:NamedThing	high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity	Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum.	got7fsn_ti	acetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity											EC:2.4.1.197|MetaCyc:2.4.1.197-RXN		molecular_function											owl:Class	
GO:0043436	biolink:NamedThing	oxoacid metabolic process	The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).	got7fsn_ti	oxoacid metabolism|keto acid metabolic process|ketoacid metabolic process|ketoacid metabolism|keto acid metabolism|oxo acid metabolism|oxo acid metabolic process													biological_process											owl:Class	
GO:0097548	biolink:NamedThing	seed abscission	The controlled shedding of a seed.	got7fsn_ti							pr	2014-01-22T07:57:41Z						biological_process											owl:Class	
GO:0005689	biolink:NamedThing	U12-type spliceosomal complex	Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.	got7fsn_ti	minor (U12-type) spliceosomal complex|minor spliceosomal complex|AT-AC spliceosomal complex											Wikipedia:Minor_spliceosome		cellular_component											owl:Class	
GO:0043200	biolink:NamedThing	response to amino acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.	got7fsn_ti	response to amino acid stimulus										GO:0010237			biological_process											owl:Class	
GO:0047347	biolink:NamedThing	aldose-1-phosphate nucleotidyltransferase activity	Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose.	got7fsn_ti	sugar nucleotide phosphorylase activity|NDP sugar phosphorylase activity|nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase activity|nucleoside diphosphosugar phosphorylase activity|NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity|sugar phosphate nucleotidyltransferase activity|NDP-aldose phosphorylase activity|glucose 1-phosphate inosityltransferase activity|NDP:aldose-1-phosphate nucleotidyltransferase activity|NDP-sugar phosphorylase activity|NDPaldose phosphorylase activity|sugar-1-phosphate nucleotidyltransferase activity											MetaCyc:2.7.7.37-RXN|EC:2.7.7.37		molecular_function											owl:Class	
GO:0050550	biolink:NamedThing	pinene synthase activity	Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate.	got7fsn_ti	geranyl-diphosphate diphosphate-lyase (cyclizing, pinene-forming)|(-)-(1S,5S)-pinene synthase activity|geranyldiphosphate diphosphate lyase (pinene forming)|beta-geraniolene synthase activity											EC:4.2.3.14|MetaCyc:4.2.3.14-RXN		molecular_function											owl:Class	
GO:0047440	biolink:NamedThing	2-dehydro-3-deoxy-D-pentonate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate.	got7fsn_ti	2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase activity|2-keto-3-deoxy-D-pentonate aldolase activity|3-deoxy-D-pentulosonic acid aldolase											EC:4.1.2.28|MetaCyc:4.1.2.28-RXN|KEGG_REACTION:R01782|RHEA:20609		molecular_function											owl:Class	
GO:0005844	biolink:NamedThing	polysome	A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.	got7fsn_ti	polyribosome											Wikipedia:Polysome|NIF_Subcellular:sao1038025871		cellular_component											owl:Class	
GO:0008453	biolink:NamedThing	alanine-glyoxylate transaminase activity	Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine.	got7fsn_ti	alanine-glyoxylate aminotransferase activity|AGT activity|L-alanine:glyoxylate aminotransferase activity|alanine--glyoxylate aminotransferase activity|alanine-glyoxylic aminotransferase activity|L-alanine-glycine transaminase activity											Reactome:R-HSA-904864|EC:2.6.1.44|Reactome:R-HSA-389684|RHEA:24248|MetaCyc:ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0033994	biolink:NamedThing	glucuronan lyase activity	Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.	got7fsn_ti	(1,4)-beta-D-glucuronan lyase activity											EC:4.2.2.14|MetaCyc:4.2.2.14-RXN		molecular_function											owl:Class	
GO:0032595	biolink:NamedThing	B cell receptor transport within lipid bilayer	The directed movement of a B cell receptor within a lipid bilayer.	got7fsn_ti	BCR translocation within membrane|BCR transport within lipid bilayer|B cell receptor translocation within membrane													biological_process											owl:Class	
GO:0045695	biolink:NamedThing	negative regulation of embryo sac egg cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation.	got7fsn_ti	negative regulation of female gametophyte egg cell differentiation|inhibition of female gametophyte egg cell differentiation|down regulation of female gametophyte egg cell differentiation|downregulation of female gametophyte egg cell differentiation|down-regulation of female gametophyte egg cell differentiation													biological_process											owl:Class	
GO:0075070	biolink:NamedThing	adhesion of symbiont hyphopodium to host	The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	adhesion of symbiont hyphopodium to host during symbiotic interaction				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0031552	biolink:NamedThing	negative regulation of brain-derived neurotrophic factor-activated receptor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.	got7fsn_ti	negative regulation of BDNF receptor activity|inhibition of brain-derived neurotrophic factor receptor activity|down-regulation of brain-derived neurotrophic factor receptor activity|downregulation of brain-derived neurotrophic factor receptor activity|down regulation of brain-derived neurotrophic factor receptor activity|negative regulation of brain-derived neurotrophic factor receptor activity													biological_process											owl:Class	
GO:0031549	biolink:NamedThing	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.	got7fsn_ti	down-regulation of brain-derived neurotrophic factor receptor signaling pathway|inhibition of brain-derived neurotrophic factor receptor signaling pathway|down regulation of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of BDNF receptor signaling pathway|downregulation of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of brain-derived neurotrophic factor receptor signalling pathway|negative regulation of BDNF receptor signalling pathway													biological_process											owl:Class	
GO:0048494	biolink:NamedThing	chromatophore ribulose bisphosphate carboxylase complex	A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.	got7fsn_ti	RubisCO complex													cellular_component											owl:Class	
GO:0075139	biolink:NamedThing	response to host iron concentration	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response of symbiont to host iron concentration				Note that this term is used to annotate gene products of the symbiont.									biological_process											owl:Class	
GO:0097587	biolink:NamedThing	MutLgamma complex	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3.	got7fsn_ti							pr	2014-03-06T11:48:12Z						cellular_component											owl:Class	
GO:0033416	biolink:NamedThing	UGG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UGG codon.	got7fsn_ti	TGG codon-amino acid adaptor activity|tryptophan tRNA				Note that in the standard genetic code, TGG codes for tryptophan.									molecular_function											owl:Class	
GO:0010358	biolink:NamedThing	leaf shaping	The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed.	got7fsn_ti	leaf structural organization													biological_process											owl:Class	
GO:0047188	biolink:NamedThing	aromatic-hydroxylamine O-acetyltransferase activity	Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl.	got7fsn_ti	N,O-acetyltransferase activity|arylhydroxamic acid N,O-acetyltransferase activity|arylhydroxamic acyltransferase activity|aromatic hydroxylamine acetyltransferase activity|arylhydroxamate acyltransferase activity|N-hydroxy-2-acetylaminofluorene N-O acyltransferase activity|N-hydroxy-4-acetylaminobiphenyl:N-hydroxy-4-aminobiphenyl O-acetyltransferase activity											RHEA:20325|EC:2.3.1.56|MetaCyc:2.3.1.56-RXN		molecular_function											owl:Class	
GO:0004523	biolink:NamedThing	RNA-DNA hybrid ribonuclease activity	Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.	got7fsn_ti	hybrid nuclease activity|hybridase (ribonuclease H)|RNase H3 activity|RNase H activity|calf thymus ribonuclease H activity|ribonuclease H3 activity|RNase H1 activity|hybridase activity|ribonuclease H activity|endoribonuclease H|RNA*DNA hybrid ribonucleotidohydrolase activity|ribonuclease H2 activity|hybrid ribonuclease activity|ribonuclease H1 activity|endoribonuclease H (calf thymus)|RNase H2 activity|endoribonuclease0 H activity				Note that the EC recommended name for this enzyme activity is 'calf thymus ribonuclease H', even though it is found in many species.						GO:0004524	Reactome:R-HSA-164528|Reactome:R-HSA-173769|Reactome:R-HSA-164519|Reactome:R-HSA-182859|EC:3.1.26.4|MetaCyc:3.1.26.4-RXN|Reactome:R-HSA-182795		molecular_function											owl:Class	
GO:0102861	biolink:NamedThing	1-18:2-2-18:1-phosphatidylcholine desaturase activity (SN2-18:2 forming)	Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8328|EC:1.14.19.22		molecular_function											owl:Class	
GO:0030409	biolink:NamedThing	glutamate formimidoyltransferase activity	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate.	got7fsn_ti	formimidoyltransferase activity|glutamate formyltransferase activity|formiminoglutamic formiminotransferase activity|glutamate formiminotransferase activity|formiminoglutamic acid transferase activity|5-formimidoyltetrahydrofolate:L-glutamate N-formimidoyltransferase activity|formiminotransferase activity	https://github.com/geneontology/go-ontology/issues/20486									GO:0030407	RHEA:15097|MetaCyc:GLUTAMATE-FORMIMINOTRANSFERASE-RXN|EC:2.1.2.5		molecular_function											owl:Class	
GO:0044180	biolink:NamedThing	filamentous growth of a unicellular organism	The process in which a unicellular organism grows in a threadlike, filamentous shape.	got7fsn_ti							jl	2009-09-25T10:16:01Z						biological_process											owl:Class	
GO:0071678	biolink:NamedThing	olfactory bulb axon guidance	The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues.	got7fsn_ti	olfactory bulb axon pathfinding						mah	2010-02-17T02:09:34Z						biological_process											owl:Class	
GO:0009392	biolink:NamedThing	N-acetyl-anhydromuramoyl-L-alanine amidase activity	Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala.	got7fsn_ti												MetaCyc:RXN0-5225		molecular_function											owl:Class	
GO:0050612	biolink:NamedThing	arsenate reductase (donor) activity	Catalysis of the reaction: A + arsenite + H(2)O = AH(2) + arsenate + 2 H(+).	got7fsn_ti	arsenate:acceptor oxidoreductase activity|arsenate:(acceptor) oxidoreductase activity											KEGG_REACTION:R05752|RHEA:18449|EC:1.20.99.1|MetaCyc:1.20.99.1-RXN		molecular_function											owl:Class	
GO:0070837	biolink:NamedThing	dehydroascorbic acid transport	The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.	got7fsn_ti	dehydroascorbate transport						mah	2009-07-30T05:24:31Z						biological_process											owl:Class	
GO:0002410	biolink:NamedThing	plasmacytoid dendritic cell chemotaxis	The movement of a plasmacytoid dendritic cell in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0072184	biolink:NamedThing	renal vesicle progenitor cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.	got7fsn_ti							mah	2010-02-26T02:52:54Z						biological_process											owl:Class	
GO:0097321	biolink:NamedThing	cell growth mode switching, filamentous to budding	The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.	got7fsn_ti							pr	2012-06-05T11:28:06Z						biological_process											owl:Class	
GO:0070784	biolink:NamedThing	regulation of growth of unicellular organism as a thread of attached cells	Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.	got7fsn_ti							mah	2009-07-07T02:34:59Z						biological_process											owl:Class	
GO:0034843	biolink:NamedThing	2-oxoglutaryl-CoA thioesterase activity	Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH.	got7fsn_ti												UM-BBD_reactionID:r1238		molecular_function											owl:Class	
GO:0102257	biolink:NamedThing	1-16:0-2-18:2-phosphatidylcholine sn-1 acylhydrolase activity	Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O <=> 1-linoleoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+.	got7fsn_ti												MetaCyc:RXN-12430		molecular_function											owl:Class	
GO:0140417	biolink:NamedThing	ATP-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a ATP has been bound by the channel complex or one of its constituent parts.	got7fsn_ti							pg	2020-01-27T09:22:04Z						molecular_function											owl:Class	
GO:1902224	biolink:NamedThing	ketone body metabolic process	The chemical reactions and pathways involving ketone body.	got7fsn_ti	ketone body metabolism						pr	2013-06-13T10:37:54Z						biological_process											owl:Class	
GO:0001601	biolink:NamedThing	peptide YY receptor activity	Combining with gut peptide YY to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0050600	biolink:NamedThing	myristoyl-CoA 11-(E) desaturase activity	Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O.	got7fsn_ti	n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(E) desaturating]|n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating]											RHEA:46396|EC:1.14.19.24|MetaCyc:1.14.99.31-RXN		molecular_function											owl:Class	
GO:0103050	biolink:NamedThing	isobutyraldehyde reductase activity	Catalysis of the reaction: isobutanol + NADP <=> isobutyraldehyde + NADPH + H+.	got7fsn_ti												MetaCyc:RXN0-7119		molecular_function											owl:Class	
GO:0034749	biolink:NamedThing	Scrib-APC complex	A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation.	got7fsn_ti	hScrib-APC complex				Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0046773	biolink:NamedThing	suppression by virus of host translation termination	Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA.	got7fsn_ti	negative regulation by virus of host cell protein biosynthetic process shutoff|viral inhibition of termination of host cell protein biosynthetic process|viral inhibition of host cell protein biosynthesis shutoff|suppression by virus of host termination of protein biosynthetic process|viral suppression of termination by host of host cell protein biosynthetic process|viral inhibition of termination of host cell protein biosynthesis|viral inhibition of host cell protein biosynthetic process shutoff|viral suppression of termination by host of host cell protein biosynthesis|negative regulation by virus of host cell protein biosynthesis shutoff													biological_process											owl:Class	
GO:0031468	biolink:NamedThing	nuclear membrane reassembly	The reformation of the nuclear membranes following their breakdown in the context of a normal process.	got7fsn_ti	nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636												biological_process											owl:Class	
GO:0140368	biolink:NamedThing	decoy receptor complex	A receptor complex that recognizes, binds and sequesters a specific receptor ligand to prevent it from binding to its regular receptor. May be soluble or membrane bound.	got7fsn_ti	osteoclastogenesis inhibitory factor|osteoprotegerin complex						pg	2019-09-13T16:39:24Z						cellular_component											owl:Class	
GO:2001137	biolink:NamedThing	positive regulation of endocytic recycling	Any process that activates or increases the frequency, rate or extent of endocytic recycling.	got7fsn_ti	positive regulation of retrograde transport of endocytic vesicles						kmv	2011-10-14T03:34:49Z						biological_process											owl:Class	
GO:0015503	biolink:NamedThing	glutathione-regulated potassium exporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.	got7fsn_ti														molecular_function											owl:Class	
GO:0006296	biolink:NamedThing	nucleotide-excision repair, DNA incision, 5'-to lesion	The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage.	got7fsn_ti	nucleotide-excision repair, DNA incision, 5' to lesion													biological_process											owl:Class	
GO:0061615	biolink:NamedThing	glycolytic process through fructose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.	got7fsn_ti	glycolysis through fructose-6-phosphate						dph	2014-04-08T10:08:49Z				MetaCyc:PWY-5484		biological_process											owl:Class	
GO:0071172	biolink:NamedThing	dihydromonapterin reductase activity	Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+.	got7fsn_ti							mah	2009-11-23T11:10:17Z						molecular_function											owl:Class	
GO:0102589	biolink:NamedThing	cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity	Catalysis of the reaction: cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA(5-) <=> cyanidin 3-O-(3''', 6''-O-dimalonyl-beta-glucopyranoside) + coenzyme A.	got7fsn_ti												MetaCyc:RXN-15336		molecular_function											owl:Class	
GO:0035693	biolink:NamedThing	NOS2-CD74 complex	A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases.	got7fsn_ti							bf	2011-02-25T11:35:38Z						cellular_component											owl:Class	
GO:0018180	biolink:NamedThing	protein desulfurization	The removal of a sulfur group from a protein amino acid.	got7fsn_ti	protein amino acid desulfurization|protein amino acid desulfurisation|protein amino acid desulphurisation|protein amino acid desulphurization													biological_process											owl:Class	
GO:0034936	biolink:NamedThing	4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity	Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0959		molecular_function											owl:Class	
GO:0018636	biolink:NamedThing	phenanthrene 9,10-monooxygenase activity	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide.	got7fsn_ti												UM-BBD_reactionID:r0495|EC:1.14.13.-		molecular_function											owl:Class	
GO:0061441	biolink:NamedThing	renal artery morphogenesis	The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.	got7fsn_ti							dph	2012-03-08T12:42:09Z						biological_process											owl:Class	
GO:0030554	biolink:NamedThing	adenyl nucleotide binding	Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0140703	biolink:NamedThing	3',3'-cyclic GMP-AMP binding	Binding to 3',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 3',5' linkages.	got7fsn_ti	3',3'-cGMP-AMP binding|3',3'-cGAMP binding|3',3'-cyclic GAMP binding|3',3' cyclic-GMP-AMP binding	https://github.com/geneontology/go-ontology/issues/21980					pg	2021-08-27T05:44:15Z						molecular_function											owl:Class	
GO:0030551	biolink:NamedThing	cyclic nucleotide binding	Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.	got7fsn_ti														molecular_function											owl:Class	
GO:0070653	biolink:NamedThing	high-density lipoprotein particle receptor binding	Binding to a high-density lipoprotein receptor.	got7fsn_ti	high-density lipoprotein receptor binding|HDL receptor binding						mah	2009-05-28T03:44:33Z						molecular_function											owl:Class	
GO:0039501	biolink:NamedThing	suppression by virus of host type I interferon production	Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	negative regulation by virus of host type I interferon production|suppression by virus of host type I IFN production|suppression by virus of host interferon type I production						bf	2011-05-11T03:53:20Z				VZ:875		biological_process											owl:Class	
GO:0032480	biolink:NamedThing	negative regulation of type I interferon production	Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	inhibition of type I interferon production|down regulation of type I interferon production|downregulation of type I interferon production|negative regulation of type I IFN production|down-regulation of type I interferon production													biological_process											owl:Class	
GO:0002337	biolink:NamedThing	B-1a B cell differentiation	The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.	got7fsn_ti	B-1a B-lymphocyte differentiation|B-1a B lymphocyte differentiation|B-1a B cell development|B-1a B-cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0071321	biolink:NamedThing	cellular response to cGMP	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.	got7fsn_ti	cellular response to 3',5' cGMP|cellular response to 3',5'-cGMP|cellular response to cyclic GMP|cellular response to guanosine 3',5'-cyclophosphate						mah	2009-12-10T05:12:58Z						biological_process											owl:Class	
GO:0070305	biolink:NamedThing	response to cGMP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.	got7fsn_ti	response to 3',5'-cGMP|response to guanosine 3',5'-cyclophosphate|response to 3',5' cGMP|response to cyclic GMP													biological_process											owl:Class	
GO:0010291	biolink:NamedThing	carotene beta-ring hydroxylase activity	Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene.	got7fsn_ti	beta-carotene hydroxylase activity										GO:0042411			molecular_function											owl:Class	
GO:0042124	biolink:NamedThing	1,3-beta-glucanosyltransferase activity	Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation.	got7fsn_ti														molecular_function											owl:Class	
GO:0070481	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, non-stop decay	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.	got7fsn_ti	non-stop mRNA decay|non-stop decay|nonstop mRNA decay|nuclear-transcribed mRNA catabolism, non-stop decay|nuclear-transcribed mRNA degradation, non-stop decay|nuclear-transcribed mRNA breakdown, non-stop decay													biological_process											owl:Class	
GO:0035106	biolink:NamedThing	operant conditioning	Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.	got7fsn_ti	instrumental conditioning											Wikipedia:Operant_conditioning		biological_process											owl:Class	
GO:0047004	biolink:NamedThing	UDP-N-acetylglucosamine 6-dehydrogenase activity	Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate.	got7fsn_ti	UDP-GLcNAc dehydrogenase activity|UDPacetylglucosamine dehydrogenase activity|UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase activity|uridine diphosphoacetylglucosamine dehydrogenase activity|UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase activity											EC:1.1.1.136|RHEA:13325|MetaCyc:1.1.1.136-RXN|KEGG_REACTION:R00421		molecular_function											owl:Class	
GO:0020036	biolink:NamedThing	Maurer's cleft	A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.	got7fsn_ti	Maurers cleft													cellular_component											owl:Class	
GO:0050828	biolink:NamedThing	regulation of liquid surface tension	Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid.	got7fsn_ti	surfactant activity|regulation of surface tension of a liquid													biological_process											owl:Class	
GO:1901320	biolink:NamedThing	negative regulation of heart induction	Any process that stops, prevents or reduces the frequency, rate or extent of heart induction.	got7fsn_ti	down-regulation of heart induction|downregulation of heart induction|down regulation of heart induction|inhibition of heart induction						bf	2012-08-28T15:48:38Z						biological_process											owl:Class	
GO:0050329	biolink:NamedThing	tetrahydroxypteridine cycloisomerase activity	Catalysis of the reaction: tetrahydroxypteridine = H(+) + xanthine-8-carboxylate.	got7fsn_ti	tetrahydroxypteridine lyase (isomerizing)											MetaCyc:TETRAHYDROXYPTERIDINE-CYCLOISOMERASE-RXN|KEGG_REACTION:R04154|EC:5.5.1.3|RHEA:18097		molecular_function											owl:Class	
GO:0062181	biolink:NamedThing	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	Catatlysis of the reaction: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin].	got7fsn_ti							dph	2019-11-26T17:16:39Z				RHEA:49192		molecular_function											owl:Class	
GO:0102459	biolink:NamedThing	8-oxo-deoxyadenine diphosphate phosphatase activity	Catalysis of the reaction: 8-oxo-dADP + H2O = 8-oxo-dAMP + hydrogenphosphate + H+.	got7fsn_ti												MetaCyc:RXN-14005		molecular_function											owl:Class	
GO:0160003	biolink:NamedThing	mono-ADP-D-ribose modification-dependent protein binding	Binding to a protein upon mono-ADP-ribosylation of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require a mono-ADP-D-ribose post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the ADP-D-ribose modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		rl	2021-07-12T23:36:00Z						molecular_function											owl:Class	
GO:0034737	biolink:NamedThing	ergosterol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester.	got7fsn_ti														molecular_function											owl:Class	
GO:0102145	biolink:NamedThing	(3R)-(E)-nerolidol synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O <=> (3R,6E)-nerolidol + diphosphoric acid.	got7fsn_ti												RHEA:27534|EC:4.2.3.49|MetaCyc:RXN-11575		molecular_function											owl:Class	
GO:0102773	biolink:NamedThing	dihydroceramide kinase activity	Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate.	got7fsn_ti												MetaCyc:RXN-7799|EC:2.7.1.138		molecular_function											owl:Class	
GO:0009447	biolink:NamedThing	putrescine catabolic process	The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine.	got7fsn_ti	putrescine degradation|putrescine catabolism|putrescine breakdown													biological_process											owl:Class	
GO:0045997	biolink:NamedThing	negative regulation of ecdysteroid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.	got7fsn_ti	down-regulation of ecdysteroid biosynthetic process|downregulation of ecdysteroid biosynthetic process|negative regulation of ecdysteroid synthesis|negative regulation of ecdysteroid anabolism|inhibition of ecdysteroid biosynthetic process|down regulation of ecdysteroid biosynthetic process|negative regulation of ecdysteroid biosynthesis|negative regulation of ecdysteroid formation													biological_process											owl:Class	
GO:0039600	biolink:NamedThing	induction by virus of host endonucleolytic cleavage-dependent mRNA catabolic process	The process in which a virus increases the frequency, rate or extent of the breakdown of host nuclear-transcribed mRNAs that begins with endonucleolytic cleavage (by either a host or a viral RNAse) to generate unprotected ends.	got7fsn_ti	induction by virus of host nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay|induction by virus of host endonucleolytic cleavage-dependent mRNA decay				Some viruses utilize a host RNase to induce endonucleolytic cleavage of template mRNAs (e.g. the NSP1 protein of SARS coronavirus); for these consider instead annotating to the child term 'induction by virus of host endoribonuclease activity ; GO:0039597'. Other viral proteins act as endonucleases themselves to cleave mRNA and then rely on the host degradation machinery to clear the resulting fragments (e.g. gamma herpesvirus SOX protein); for these cases consider instead annotating to the child term 'endoribonuclease activity involved in viral induction of host mRNA catabolic process ; GO:0039594'.		bf	2012-07-04T05:23:43Z						biological_process											owl:Class	
GO:0009821	biolink:NamedThing	alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).	got7fsn_ti	alkaloid synthesis|alkaloid formation|alkaloid anabolism|alkaloid biosynthesis											UM-BBD_enzymeID:e0711		biological_process											owl:Class	
GO:0051788	biolink:NamedThing	response to misfolded protein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0050474	biolink:NamedThing	(S)-norcoclaurine synthase activity	Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O.	got7fsn_ti	4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]|(S)-norlaudanosoline synthase activity|4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine)										GO:0050475	EC:4.2.1.78|RHEA:16173|MetaCyc:S-NORLAUDANOSOLINE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0016340	biolink:NamedThing	calcium-dependent cell-matrix adhesion	The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0004150	biolink:NamedThing	dihydroneopterin aldolase activity	Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde.	got7fsn_ti	2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming)|2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase activity											EC:4.1.2.25|MetaCyc:H2NEOPTERINALDOL-RXN|RHEA:10540		molecular_function											owl:Class	
GO:0031715	biolink:NamedThing	C5L2 anaphylatoxin chemotactic receptor binding	Binding to a C5L2 anaphylatoxin chemotactic receptor.	got7fsn_ti	C5L2 anaphylatoxin chemotactic receptor ligand													molecular_function											owl:Class	
GO:0031714	biolink:NamedThing	C5a anaphylatoxin chemotactic receptor binding	Binding to a C5a anaphylatoxin chemotactic receptor.	got7fsn_ti	C5a anaphylatoxin chemotactic receptor ligand													molecular_function											owl:Class	
GO:0004463	biolink:NamedThing	leukotriene-A4 hydrolase activity	Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4).	got7fsn_ti	LTA4H|LTA-4 hydrolase activity|leukotriene A4 hydrolase activity|(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity|leukotriene A(4) hydrolase activity|LTA4 hydrolase activity											EC:3.3.2.6|Reactome:R-HSA-266072|KEGG_REACTION:R03057|RHEA:22324|MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN		molecular_function											owl:Class	
GO:0102615	biolink:NamedThing	ent-cassadiene-C2-hydroxylase activity	Catalysis of the reaction: ent-cassa-12,15-diene + NADPH + O2 + H+ <=> 2alpha-hydroxy-ent-cassadiene + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15462|RHEA:55484		molecular_function											owl:Class	
GO:0047447	biolink:NamedThing	erythro-3-hydroxyaspartate ammonia-lyase activity	Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid.	got7fsn_ti	erythro-3-hydroxy-Ls-aspartate ammonia-lyase (oxaloacetate-forming)|erythro-3-hydroxy-Ls-aspartate ammonia-lyase activity|erythro-3-hydroxy-L(s)-aspartate hydro-lyase (deaminating) activity|erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)|3-hydroxyaspartate dehydratase activity|erythro-beta-hydroxyaspartate dehydratase activity|erythro-3-hydroxyaspartate dehydratase activity											MetaCyc:4.3.1.20-RXN|RHEA:19757|EC:4.3.1.20		molecular_function											owl:Class	
GO:0004068	biolink:NamedThing	aspartate 1-decarboxylase activity	Catalysis of the reaction: L-aspartate = beta-alanine + CO2.	got7fsn_ti	aspartate alpha-decarboxylase activity|aspartic alpha-decarboxylase|L-aspartate 1-carboxy-lyase activity|L-aspartate 1-carboxy-lyase (beta-alanine-forming)|L-aspartate alpha-decarboxylase activity											EC:4.1.1.11|MetaCyc:PWY-5155|RHEA:19497|MetaCyc:ASPDECARBOX-RXN		molecular_function											owl:Class	
GO:0016496	biolink:NamedThing	substance P receptor activity	Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0010474	biolink:NamedThing	glucose-1-phosphate guanylyltransferase (GDP) activity	Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose.	got7fsn_ti	GDP:glucose-1-phosphate guanyltransferase activity													molecular_function											owl:Class	
GO:0102517	biolink:NamedThing	oleate 12-hydroxylase activity	Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-14487		molecular_function											owl:Class	
GO:0015486	biolink:NamedThing	glycoside-pentoside-hexuronide:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.	got7fsn_ti														molecular_function											owl:Class	
GO:0031416	biolink:NamedThing	NatB complex	A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p.	got7fsn_ti	N-terminal acetyltransferase B complex													cellular_component											owl:Class	
GO:0097169	biolink:NamedThing	AIM2 inflammasome complex	An inflammasome complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA.	got7fsn_ti							pr	2011-10-03T07:36:21Z						cellular_component											owl:Class	
GO:1990091	biolink:NamedThing	sodium-dependent self proteolysis	The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.	got7fsn_ti							sl	2013-05-06T17:30:23Z						biological_process											owl:Class	
GO:0032232	biolink:NamedThing	negative regulation of actin filament bundle assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.	got7fsn_ti	down-regulation of actin filament bundle formation|downregulation of actin filament bundle formation|down regulation of actin filament bundle formation|inhibition of actin filament bundle formation													biological_process											owl:Class	
GO:1990856	biolink:NamedThing	methionyl-initiator methionine tRNA binding	Binding to methionine-initator methionine tRNA.	got7fsn_ti					An example of this is eukaryotic initiation factor 2 complex, which binds the methionyl-initiator methionine tRNA during ternary complex formation. The non-acylated tRNA is not bound.		hjd	2015-09-18T16:56:59Z						molecular_function											owl:Class	
GO:0060361	biolink:NamedThing	flight	Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.	got7fsn_ti														biological_process											owl:Class	
GO:0031544	biolink:NamedThing	peptidyl-proline 3-dioxygenase activity	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.	got7fsn_ti														molecular_function											owl:Class	
GO:0051029	biolink:NamedThing	rRNA transport	The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0016941	biolink:NamedThing	natriuretic peptide receptor activity	Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0034371	biolink:NamedThing	chylomicron remodeling	The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.	got7fsn_ti	chylomicron remnant formation													biological_process											owl:Class	
GO:0034370	biolink:NamedThing	triglyceride-rich lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.	got7fsn_ti	triacylglycerol-rich lipoprotein particle remodeling													biological_process											owl:Class	
GO:0102426	biolink:NamedThing	myricetin-3-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: myricetin 3-O-beta-D-glucopyranoside + UDP-alpha-D-glucose <=> myricetin 3-O-gentiobioside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13823		molecular_function											owl:Class	
GO:0004643	biolink:NamedThing	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide.	got7fsn_ti	AICAR formyltransferase activity|aminoimidazolecarboxamide ribonucleotide transformylase activity|5-amino-4-imidazolecarboxamide ribonucleotide transformylase activity|AICAR transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity|5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity|5-amino-4-imidazolecarboxamide ribotide transformylase activity|5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase activity											RHEA:22192|Reactome:R-HSA-73798|EC:2.1.2.3|MetaCyc:AICARTRANSFORM-RXN		molecular_function											owl:Class	
GO:0000706	biolink:NamedThing	meiotic DNA double-strand break processing	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0046931	biolink:NamedThing	pore complex assembly	The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases.	got7fsn_ti	pore-forming toxin activity|pore complex biogenesis|pore formation|pore biosynthesis				See also the cellular component term 'pore complex ; GO:0046930'.									biological_process											owl:Class	
GO:0102248	biolink:NamedThing	diacylglycerol transacylase activity	Catalysis of the reaction: 2 a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 2-monoglyceride.	got7fsn_ti												MetaCyc:RXN-12383		molecular_function											owl:Class	
GO:1900970	biolink:NamedThing	positive regulation of sarcinapterin metabolic process	Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process.	got7fsn_ti	activation of sarcinapterin metabolic process|upregulation of sarcinapterin metabolism|upregulation of sarcinapterin metabolic process|up regulation of sarcinapterin metabolism|up regulation of sarcinapterin metabolic process|up-regulation of sarcinapterin metabolism|activation of sarcinapterin metabolism|up-regulation of sarcinapterin metabolic process|positive regulation of sarcinapterin metabolism						tt	2012-06-14T03:58:43Z						biological_process											owl:Class	
GO:0045864	biolink:NamedThing	positive regulation of pteridine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine.	got7fsn_ti	upregulation of pteridine metabolic process|up regulation of pteridine metabolic process|stimulation of pteridine metabolic process|activation of pteridine metabolic process|positive regulation of pteridine metabolism|up-regulation of pteridine metabolic process													biological_process											owl:Class	
GO:0018577	biolink:NamedThing	catechol 2,3-dioxygenase activity	Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.	got7fsn_ti	catechol oxygenase|2,3-pyrocatechase activity|pyrocatechol 2,3-dioxygenase|catechol 2,3-oxygenase|cato2ase activity|metapyrocatechase activity|catechol:oxygen 2,3-oxidoreductase (decyclizing)											MetaCyc:CATECHOL-23-DIOXYGENASE-RXN|UM-BBD_enzymeID:e0156|RHEA:17337|EC:1.13.11.2		molecular_function											owl:Class	
GO:0034377	biolink:NamedThing	plasma lipoprotein particle assembly	The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle.	got7fsn_ti														biological_process											owl:Class	
GO:0031738	biolink:NamedThing	XCR1 chemokine receptor binding	Binding to a XCR1 chemokine receptor.	got7fsn_ti	XCR1 chemokine receptor ligand|lymphotactin receptor binding													molecular_function											owl:Class	
GO:0061141	biolink:NamedThing	lung ciliated cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.	got7fsn_ti							dph	2010-05-25T09:31:14Z						biological_process											owl:Class	
GO:0043990	biolink:NamedThing	histone H2A-S1 phosphorylation	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 1 of the histone.	got7fsn_ti	histone H2AS1 phosphorylation|histone H2A phosphorylation at S1													biological_process											owl:Class	
GO:0018213	biolink:NamedThing	peptidyl-valine modification	The modification of peptidyl-valine.	got7fsn_ti														biological_process											owl:Class	
GO:0060030	biolink:NamedThing	dorsal convergence	The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.	got7fsn_ti														biological_process											owl:Class	
GO:0102332	biolink:NamedThing	fatty-acyl-[acp] elongase/decarboxylase activity	Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-13260		molecular_function											owl:Class	
GO:0010370	biolink:NamedThing	perinucleolar chromocenter	A chromocenter adjacent to the nucleolus.	got7fsn_ti														cellular_component											owl:Class	
GO:0010369	biolink:NamedThing	chromocenter	A region in which centric, heterochromatic portions from more than one chromosomes form a compact structure.	got7fsn_ti														cellular_component											owl:Class	
GO:0050584	biolink:NamedThing	linoleate 11-lipoxygenase activity	Catalysis of the reaction: linoleate + O(2) = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate.	got7fsn_ti	linoleate:oxygen 11S-oxidoreductase activity|manganese lipoxygenase activity|linoleate dioxygenase activity											EC:1.13.11.45|MetaCyc:1.13.11.45-RXN|RHEA:18993|KEGG_REACTION:R05718		molecular_function											owl:Class	
GO:0021520	biolink:NamedThing	spinal cord motor neuron cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.	got7fsn_ti														biological_process											owl:Class	
GO:0016330	biolink:NamedThing	second mitotic wave involved in compound eye morphogenesis	A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia.	got7fsn_ti	second mitotic wave during compound eye morphogenesis													biological_process											owl:Class	
GO:0031747	biolink:NamedThing	type 2 cysteinyl leukotriene receptor binding	Binding to a type 2 cysteinyl leukotriene receptor.	got7fsn_ti	type 2 cysteinyl leukotriene receptor ligand													molecular_function											owl:Class	
GO:0002487	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class I via endolysosomal pathway													biological_process											owl:Class	
GO:0010283	biolink:NamedThing	pinoresinol reductase activity	Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+.	got7fsn_ti												MetaCyc:RXN-8683|MetaCyc:RXN-8678		molecular_function											owl:Class	
GO:0103085	biolink:NamedThing	2-(5'-methylthio)pentylmalate synthase activity	Catalysis of the reaction: 2-oxo-7-methylthioheptanoate + acetyl-CoA + H2O <=> H+ + 2-(5'-methylthio)pentylmalate + coenzyme A.	got7fsn_ti												MetaCyc:RXNQT-4169		molecular_function											owl:Class	
GO:0006625	biolink:NamedThing	protein targeting to peroxisome	The process of directing proteins towards the peroxisome, usually using signals contained within the protein.	got7fsn_ti	protein-peroxisome targeting													biological_process											owl:Class	
GO:0106317	biolink:NamedThing	methane monooxygenase NADH activity	Catalysis of the reaction: methane + NADH + H+ + O2 = methanol + NAD+ + H2O.	got7fsn_ti							hjd	2020-09-23T15:12:25Z				RHEA:13637|EC:1.14.13.25		molecular_function											owl:Class	
GO:0052830	biolink:NamedThing	inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate.	got7fsn_ti							ai	2011-11-29T10:56:59Z				Reactome:R-HSA-1855171		molecular_function											owl:Class	
GO:0036429	biolink:NamedThing	adenosylcobinamide kinase (ATP-specific) activity	Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+.	got7fsn_ti							bf	2013-09-16T14:05:56Z				RHEA:15769|KEGG_REACTION:R05221|MetaCyc:COBINAMIDEKIN-RXN		molecular_function											owl:Class	
GO:0036420	biolink:NamedThing	extrinsic component of mycolate outer membrane	The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to mycolate outer membrane|extrinsic to mycomembrane|extrinsic to MOM						bf	2013-09-05T20:22:02Z						cellular_component											owl:Class	
GO:0006718	biolink:NamedThing	juvenile hormone biosynthetic process	The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	got7fsn_ti	juvenile hormone synthesis|juvenile hormone biosynthesis|juvenile hormone anabolism|juvenile hormone formation													biological_process											owl:Class	
GO:0045840	biolink:NamedThing	positive regulation of mitotic nuclear division	Any process that activates or increases the frequency, rate or extent of mitosis.	got7fsn_ti	up-regulation of mitosis|upregulation of mitosis|mitogenic activity|up regulation of mitosis|stimulation of mitosis|positive regulation of mitosis|activation of mitosis													biological_process											owl:Class	
GO:0005004	biolink:NamedThing	GPI-linked ephrin receptor activity	Combining with a GPI-anchored ephrin to initiate a change in cell activity.	got7fsn_ti	GPI-linked Eph receptor activity													molecular_function											owl:Class	
GO:0005003	biolink:NamedThing	ephrin receptor activity	Combining with an ephrin to initiate a change in cell activity.	got7fsn_ti	Eph receptor activity													molecular_function											owl:Class	
GO:0070767	biolink:NamedThing	BRCA1-Rad51 complex	A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity.	got7fsn_ti							mah	2009-06-29T05:04:21Z						cellular_component											owl:Class	
GO:0004746	biolink:NamedThing	riboflavin synthase activity	Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin.	got7fsn_ti	6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase activity|riboflavin synthetase activity|light riboflavin synthase|riboflavine synthetase activity|heavy riboflavin synthase|riboflavine synthase activity|vitamin B2 synthase activity|lumazine synthase activity											RHEA:20772|EC:2.5.1.9|KEGG_REACTION:R00066|MetaCyc:RIBOFLAVIN-SYN-RXN		molecular_function											owl:Class	
GO:0071727	biolink:NamedThing	cellular response to triacyl bacterial lipopeptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.	got7fsn_ti	cellular response to triacylated bacterial lipoprotein				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:17:49Z						biological_process											owl:Class	
GO:0120285	biolink:NamedThing	tyrosine sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of tyrosine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20181					krc	2020-11-18T01:19:42Z						molecular_function											owl:Class	
GO:0072545	biolink:NamedThing	tyrosine binding	Binding to 2-amino-3-(4-hydroxyphenyl)propanoic acid.	got7fsn_ti	Tyr binding						mah	2011-01-19T05:43:55Z						molecular_function											owl:Class	
GO:2000292	biolink:NamedThing	regulation of defecation	Any process that modulates the frequency, rate or extent of defecation.	got7fsn_ti							bf	2010-12-21T09:23:08Z						biological_process											owl:Class	
GO:0004671	biolink:NamedThing	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.	got7fsn_ti	prenylcysteine methyltransferase activity|farnesyl-protein carboxymethyltransferase activity|prenylated protein methyltransferase activity|prenylcysteine carboxylmethyltransferase activity|farnesyl cysteine C-terminal methyltransferase activity|prenylcysteine carboxymethyltransferase activity|farnesylated protein C-terminal O-methyltransferase activity|isoprenylated protein methyltransferase activity|prenylcysteine carboxyl methyltransferase activity|protein-S-isoprenylcysteine O-methyltransferase activity|S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity|protein S-farnesylcysteine C-terminal methyltransferase activity|protein C-terminal farnesylcysteine O-methyltransferase activity|prenylated protein carboxyl methyltransferase activity|isoprenylcysteine carboxylmethyltransferase activity|S-farnesylcysteine methyltransferase activity										GO:0018225	EC:2.1.1.100|Reactome:R-HSA-6788650|MetaCyc:2.1.1.100-RXN|RHEA:21672|KEGG_REACTION:R04496|Reactome:R-HSA-9647977		molecular_function											owl:Class	
GO:0004419	biolink:NamedThing	hydroxymethylglutaryl-CoA lyase activity	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.	got7fsn_ti	3-hydroxy-3-methylglutaryl-CoA lyase activity|hydroxymethylglutaryl coenzyme A-cleaving enzyme|HMG-CoA lyase activity|hydroxymethylglutaryl coenzyme A lyase activity|3-hydroxy-3-methylglutarate-CoA lyase activity|3-hydroxy-3-methylglutaryl coenzyme A lyase activity|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)|3-hydroxy-3-methylglutaryl CoA cleaving enzyme|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity											EC:4.1.3.4|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN|Reactome:R-HSA-6788597|Reactome:R-HSA-74180|KEGG_REACTION:R01360|RHEA:24404		molecular_function											owl:Class	
GO:0102114	biolink:NamedThing	caprate dehydroxylase activity	Catalysis of the reaction: decanoate + NADPH + O2 + H+ <=> 10-hydroxycaprate + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-11325		molecular_function											owl:Class	
GO:0106148	biolink:NamedThing	4-hydroxyindole-3- carbonyl nitrile biosynthesis	The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside.	got7fsn_ti							hjd	2018-09-10T19:42:16Z						biological_process											owl:Class	
GO:0051360	biolink:NamedThing	peptide cross-linking via L-asparagine 5-imidazolinone glycine	The formation of the fluorescent protein FP506 chromophore cross-link from the alpha-carboxyl carbon of residue n, an asparagine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	got7fsn_ti	biosynthesis of protein-protein cross-link via L-asparagine 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via L-asparagine 5-imidazolinone glycine				See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.							RESID:AA0380		biological_process											owl:Class	
GO:0018902	biolink:NamedThing	1,3-dichloro-2-propanol metabolic process	The chemical reactions and pathways involving 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. DCP is used as a general solvent, as an intermediate in organic synthesis and in paints, varnishes, lacquers, water colors, binders and photographic lacquers.	got7fsn_ti	1,3-dichloro-2-propanol metabolism|DCP metabolic process|DCP metabolism											UM-BBD_pathwayID:dcp		biological_process											owl:Class	
GO:0044102	biolink:NamedThing	purine deoxyribosyltransferase activity	Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor.	got7fsn_ti	purine 2'-deoxyribosyltransferase activity|PTD						jl	2009-07-09T03:40:15Z						molecular_function											owl:Class	
GO:0052900	biolink:NamedThing	spermine oxidase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: H(2)O + O(2) + spermine = 1,3-diaminopropane + H(2)O(2) + N-(3-aminopropyl)-4-aminobutanal.	got7fsn_ti	polyamine oxidase (propane-1,3-diamine-forming) activity											MetaCyc:RXN-6421|EC:1.5.3.14|RHEA:25824		molecular_function											owl:Class	
GO:0070185	biolink:NamedThing	mitochondrial valyl-tRNA aminoacylation	The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0021752	biolink:NamedThing	inferior salivary nucleus development	The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0051989	biolink:NamedThing	coproporphyrinogen dehydrogenase activity	Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.	got7fsn_ti	coproporphyrinogen III oxidase activity|HemN|coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)|oxygen-independent coproporphyrinogen-III oxidase activity|radical SAM enzyme activity											EC:1.3.98.3|MetaCyc:HEMN-RXN|RHEA:15425		molecular_function											owl:Class	
GO:0004167	biolink:NamedThing	dopachrome isomerase activity	Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.	got7fsn_ti	dopachrome keto-enol isomerase activity|L-dopachrome keto-enol isomerase activity|TRP2|TRP activity|dopachrome oxidoreductase activity|L-dopachrome-methyl ester tautomerase activity|dopachrome delta7,Delta2-isomerase activity|L-dopachrome isomerase activity|dopachrome rearranging enzyme activity|dopachrome conversion activity|TRP-2|tryosinase-related protein-2|TRP-1|tyrosinase-related protein 2 activity|DCF activity|dopachrome Delta(7),Delta(2)-isomerase activity|dopachrome-rearranging enzyme|DCT activity|dopachrome conversion factor activity|dopachrome delta-isomerase activity|dopachrome tautomerase activity										GO:0048059	RHEA:13041|MetaCyc:DOPACHROME-DELTA-ISOMERASE-RXN|KEGG_REACTION:R03673|EC:5.3.3.12		molecular_function											owl:Class	
GO:0036061	biolink:NamedThing	muscle cell chemotaxis toward tendon cell	The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.	got7fsn_ti	muscle cell chemotaxis towards tendon cell|muscle cell attraction						bf	2011-12-14T11:13:40Z						biological_process											owl:Class	
GO:0097673	biolink:NamedThing	SCF-Ucc1 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae.	got7fsn_ti	SCF-YLR224W ubiquitin ligase complex						pr	2014-10-06T10:30:31Z						cellular_component											owl:Class	
GO:0050625	biolink:NamedThing	2-hydroxy-1,4-benzoquinone reductase activity	Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+).	got7fsn_ti	2-hydroxy-1,4-benzoquinone:NADH oxidoreductase activity|NADH:2-hydroxy-1,4-benzoquinone oxidoreductase activity|1,2,4-trihydroxybenzene:NAD oxidoreductase activity|hydroxybenzoquinone reductase activity|1,2,4-trihydroxybenzene:NAD+ oxidoreductase activity										GO:0018540	KEGG_REACTION:R05399|MetaCyc:1.6.5.7-RXN|EC:1.6.5.7|UM-BBD_reactionID:r0667|RHEA:12428		molecular_function											owl:Class	
GO:0140560	biolink:NamedThing	xylosyl alpha-1,3-xylosyltransferase activity	Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16869					pg	2020-11-25T13:45:18Z				RHEA:22820|EC:2.4.2.62		molecular_function											owl:Class	
GO:0047156	biolink:NamedThing	acetoin-ribose-5-phosphate transaldolase activity	Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde.	got7fsn_ti	1-deoxy-D-altro-heptulose-7-phosphate synthetase activity|3-hydroxybutan-3-one:D-ribose-5-phosphate aldehydetransferase activity|1-deoxy-D-altro-heptulose-7-phosphate synthase activity|3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase activity											MetaCyc:2.2.1.4-RXN|RHEA:21504|KEGG_REACTION:R02345|EC:2.2.1.4		molecular_function											owl:Class	
GO:1990227	biolink:NamedThing	paranodal junction maintenance	The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.	got7fsn_ti	axoglial septate junction maintenance|paranodal septate maintenance|paranodal axoglial junction maintenance						pr	2013-11-07T20:01:46Z						biological_process											owl:Class	
GO:0045217	biolink:NamedThing	cell-cell junction maintenance	The maintenance of junctions between cells.	got7fsn_ti	intercellular junction maintenance													biological_process											owl:Class	
GO:0071259	biolink:NamedThing	cellular response to magnetism	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.	got7fsn_ti	cellular response to magnetic stimulus						mah	2009-12-04T03:54:53Z						biological_process											owl:Class	
GO:0062209	biolink:NamedThing	spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.	got7fsn_ti	regulation of spatial distribution of meiotic DSB formation involved in reciprocal meiotic recombination|regulation of spatial distribution of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|DSB interference|crossover interference						dph	2020-02-03T19:19:29Z						biological_process											owl:Class	
GO:0006568	biolink:NamedThing	tryptophan metabolic process	The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.	got7fsn_ti	tryptophan metabolism											Wikipedia:Tryptophan		biological_process											owl:Class	
GO:0102048	biolink:NamedThing	indole-3-acetyl-isoleucine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-isoleucine + ATP(4-) <=> H+ + indole-3-acetyl-isoleucine + AMP(2-) + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10430		molecular_function											owl:Class	
GO:0004102	biolink:NamedThing	choline O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.	got7fsn_ti	choline acetylase activity|acetyl-CoA:choline O-acetyltransferase activity|choline acetyltransferase activity|CHOACTase activity											EC:2.3.1.6|Reactome:R-HSA-264622|KEGG_REACTION:R01023|RHEA:18821|MetaCyc:CHOLINE-O-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0018680	biolink:NamedThing	deethylatrazine monooxygenase activity	Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine.	got7fsn_ti												EC:1.14.15.-|UM-BBD_reactionID:r0128		molecular_function											owl:Class	
GO:0072548	biolink:NamedThing	dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity	Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O.	got7fsn_ti							mah	2011-01-25T02:57:22Z						molecular_function											owl:Class	
GO:0150195	biolink:NamedThing	transport across blood-cerebrospinal fluid barrier	The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier.	got7fsn_ti	transport across BCSFB|transport across blood/cerebrospinal fluid barrier|transport across blood/CSF barrier|transport across blood-CSF barrier						bc	2020-03-26T14:43:04Z						biological_process											owl:Class	
GO:0060003	biolink:NamedThing	copper ion export	The directed movement of copper ions out of a cell or organelle.	got7fsn_ti	copper export													biological_process											owl:Class	
GO:0035434	biolink:NamedThing	copper ion transmembrane transport	The directed movement of copper cation across a membrane.	got7fsn_ti	copper ion membrane transport|copper cation transmembrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T11:03:23Z			GO:1901473			biological_process											owl:Class	
GO:0033709	biolink:NamedThing	D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity	Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+.	got7fsn_ti	NADP+-dependent D-arabinitol dehydrogenase activity|ARD1p|D-arabinitol dehydrogenase 1 activity|D-arabinitol:NADP+ dehydrogenase activity											RHEA:11868|KEGG_REACTION:R07144|MetaCyc:RXN-7972		molecular_function											owl:Class	
GO:0016913	biolink:NamedThing	follicle-stimulating hormone activity	The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis.	got7fsn_ti	follicle stimulating hormone activity|FSH activity|follitropin activity													molecular_function											owl:Class	
GO:0009603	biolink:NamedThing	detection of symbiotic fungus	The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal.	got7fsn_ti	perception of symbiotic fungi|detection of symbiotic fungi|perception of symbiotic fungus													biological_process											owl:Class	
GO:0009706	biolink:NamedThing	chloroplast inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma.	got7fsn_ti	chloroplast inner envelope													cellular_component											owl:Class	
GO:0061117	biolink:NamedThing	negative regulation of heart growth	Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.	got7fsn_ti							dph	2010-05-17T07:31:28Z						biological_process											owl:Class	
GO:0034940	biolink:NamedThing	5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity	Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3.	got7fsn_ti												UM-BBD_reactionID:r0984		molecular_function											owl:Class	
GO:0102171	biolink:NamedThing	DMNT synthase activity	Catalysis of the reaction: H+ + (3S,6E)-nerolidol + NADPH + O2 <=> (E)-4,8-dimethyl-1,3,7-nonatriene + buten-2-one + NADP + 2 H2O.	got7fsn_ti												RHEA:55424|MetaCyc:RXN-11911		molecular_function											owl:Class	
GO:0005094	biolink:NamedThing	Rho GDP-dissociation inhibitor activity	Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.	got7fsn_ti														molecular_function											owl:Class	
GO:0070407	biolink:NamedThing	oxidation-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.	got7fsn_ti	oxidized protein catabolic process|oxidation-dependent protein breakdown|oxidation-dependent proteolysis|oxidation-dependent protein catabolism|oxidation-dependent protein degradation													biological_process											owl:Class	
GO:0043246	biolink:NamedThing	megasome	Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0034864	biolink:NamedThing	2,4,4-trimethylpentanal dehydrogenase activity	Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1275		molecular_function											owl:Class	
GO:0061249	biolink:NamedThing	mesonephric glomerular capillary formation	The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti							dph	2010-08-30T01:17:08Z						biological_process											owl:Class	
GO:0050637	biolink:NamedThing	lovastatin nonaketide synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+).	got7fsn_ti	acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)											RHEA:18565|KEGG_REACTION:R07251|MetaCyc:2.3.1.161-RXN|EC:2.3.1.161		molecular_function											owl:Class	
GO:0004408	biolink:NamedThing	holocytochrome-c synthase activity	Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.	got7fsn_ti	cytochrome c heme-lyase activity|holocytochrome-c apocytochrome-c-lyase activity|holocytochrome c synthetase activity|cytochrome c synthase activity|holocytochrome-c apocytochrome-c-lyase (heme-forming)											RHEA:22648|EC:4.4.1.17|MetaCyc:HOLOCYTOCHROME-C-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0070791	biolink:NamedThing	cleistothecium development	The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	got7fsn_ti							mah	2009-07-08T02:52:32Z						biological_process											owl:Class	
GO:0000909	biolink:NamedThing	sporocarp development involved in sexual reproduction	The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.	got7fsn_ti	perfect stage fruiting body development|fruiting body formation involved in sexual reproduction|ascus development|fruiting body development involved in sexual reproduction													biological_process											owl:Class	
GO:0015989	biolink:NamedThing	light-driven proton transport	The transport of protons against an electrochemical gradient, using energy from light.	got7fsn_ti														biological_process											owl:Class	
GO:0001208	biolink:NamedThing	histone H2A-H2B dimer displacement	The removal of a H2A-H2B histone dimer from a nucleosome within chromatin.	got7fsn_ti							krc	2012-03-27T11:03:40Z						biological_process											owl:Class	
GO:0005616	biolink:NamedThing	larval serum protein complex	A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0021870	biolink:NamedThing	Cajal-Retzius cell differentiation	The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene.	got7fsn_ti														biological_process											owl:Class	
GO:1990641	biolink:NamedThing	response to iron ion starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion.	got7fsn_ti							sl	2015-02-11T18:43:28Z						biological_process											owl:Class	
GO:0052081	biolink:NamedThing	modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	Any process in which an organism modulates the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of defense-related host SA-mediated signal transduction pathway by organism|modulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction										GO:0052445			biological_process											owl:Class	
GO:0002175	biolink:NamedThing	protein localization to paranode region of axon	A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon.	got7fsn_ti	protein localisation to paranode region of axon						hjd	2010-11-15T10:28:20Z						biological_process											owl:Class	
GO:0044349	biolink:NamedThing	DNA excision	The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised.	got7fsn_ti							jl	2011-08-03T10:56:37Z						biological_process											owl:Class	
GO:0018496	biolink:NamedThing	2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity	Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0205		molecular_function											owl:Class	
GO:0051675	biolink:NamedThing	isopullulanase activity	Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose).	got7fsn_ti	pullulan 4-glucanohydrolase (isopanose-forming) activity											MetaCyc:3.2.1.57-RXN|EC:3.2.1.57		molecular_function											owl:Class	
GO:0050223	biolink:NamedThing	protocatechuate decarboxylase activity	Catalysis of the reaction: 3,4-dihydroxybenzoate + H(+) = catechol + CO(2).	got7fsn_ti	3,4-dihydroxybenzoate decarboxylase activity|protocatechuate carboxy-lyase activity|3,4-dihydrobenzoate decarboxylase activity|3,4-dihydroxybenzoate carboxy-lyase (catechol-forming)											MetaCyc:PROTOCATECHUATE-DECARBOXYLASE-RXN|RHEA:22416|EC:4.1.1.63|KEGG_REACTION:R00822		molecular_function											owl:Class	
GO:0045730	biolink:NamedThing	respiratory burst	A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	got7fsn_ti	metabolic burst|oxidative burst											Wikipedia:Respiratory_burst		biological_process											owl:Class	
GO:0036239	biolink:NamedThing	taxoid 7beta-hydroxylase activity	Catalysis of the reaction: taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O.	got7fsn_ti							bf	2012-05-22T02:13:21Z				MetaCyc:RXN-12885|EC:1.14.13.147|KEGG_REACTION:R09868|RHEA:31975		molecular_function											owl:Class	
GO:0050487	biolink:NamedThing	sulfoacetaldehyde acetyltransferase activity	Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde.	got7fsn_ti	acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming)|sulphoacetaldehyde acetyltransferase activity				Note that the enzyme sulfoacetaldehyde acetyltransferase also has sulfoacetaldehyde lyase activity (GO:0050312).							RHEA:24204|MetaCyc:RXN-2364|KEGG_REACTION:R05651|EC:2.3.3.15		molecular_function											owl:Class	
GO:0150016	biolink:NamedThing	basal distal dendrite	Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma).	got7fsn_ti							bc	2017-12-21T12:11:47Z						cellular_component											owl:Class	
GO:1900732	biolink:NamedThing	regulation of polyketide biosynthetic process	Any process that modulates the frequency, rate or extent of polyketide biosynthetic process.	got7fsn_ti	regulation of polyketide formation|regulation of polyketide biosynthesis|regulation of polyketide synthesis|regulation of polyketide anabolism						di	2012-05-26T01:29:40Z						biological_process											owl:Class	
GO:0010566	biolink:NamedThing	regulation of ketone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0001125	biolink:NamedThing	transcription termination from bacterial-type RNA polymerase promoter	The process in which the synthesis of an RNA molecule by a bacterial-type RNA polymerase using a DNA template is completed.	got7fsn_ti							krc	2010-12-06T03:47:43Z						biological_process											owl:Class	
GO:0047218	biolink:NamedThing	hydroxycinnamate 4-beta-glucosyltransferase activity	Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP.	got7fsn_ti	UDP-glucose-hydroxycinnamate glucosyltransferase activity|UDPglucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-hydroxycinnamate glucosyltransferase activity|UDP-glucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity|hydroxycinnamoyl glucosyltransferase activity											RHEA:21636|MetaCyc:2.4.1.126-RXN|EC:2.4.1.126		molecular_function											owl:Class	
GO:0036165	biolink:NamedThing	invasive growth in response to heat	The growth of colonies in filamentous chains of cells as a result of an increase in temperature.	got7fsn_ti	invasive growth in response to temperature stimulus|invasive growth in response to high temperature|invasive growth in response to elevated temperature						bf	2012-03-27T11:23:03Z						biological_process											owl:Class	
GO:0009773	biolink:NamedThing	photosynthetic electron transport in photosystem I	A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP.	got7fsn_ti														biological_process											owl:Class	
GO:0140441	biolink:NamedThing	protein-cysteine S-arachidonoyltransferase activity	Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18882					pg	2020-03-11T09:56:24Z				RHEA:59748		molecular_function											owl:Class	
GO:0031716	biolink:NamedThing	calcitonin receptor binding	Binding to a calcitonin receptor.	got7fsn_ti	calcitonin receptor ligand													molecular_function											owl:Class	
GO:0090396	biolink:NamedThing	leaf papilla	A plant cell papilla that is part of a leaf papilla cell.	got7fsn_ti					Part of leaf papilla cell (PO:0025167).		tb	2010-12-15T03:26:20Z						cellular_component											owl:Class	
GO:0102779	biolink:NamedThing	cannabidiolate synthase activity	Catalysis of the reaction: cannabigerolate + O2 <=> cannabidiolate + hydrogen peroxide.	got7fsn_ti												EC:1.21.3.8|RHEA:34411|MetaCyc:RXN-7855		molecular_function											owl:Class	
GO:0102977	biolink:NamedThing	nitrilotriacetate monooxygenase activity (FMN-dependent)	Catalysis of the reaction: nitrilotriacetate + O2 + FMNH2 = ammoniodiacetate + 2-oxo monocarboxylic acid anion + H2O + FMN.	got7fsn_ti												RHEA:31359|MetaCyc:RXN-9508|EC:1.14.14.10		molecular_function											owl:Class	
GO:0050649	biolink:NamedThing	testosterone 6-beta-hydroxylase activity	Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O.	got7fsn_ti	testosterone 6b-hydroxylase activity													molecular_function											owl:Class	
GO:0052733	biolink:NamedThing	quinate 3-dehydrogenase (NADP+) activity	Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+.	got7fsn_ti	quinate:NADP 3-oxidoreductase activity|quinate:NADP(+) 3-oxidoreductase activity|quinic dehydrogenase activity						ai	2011-08-16T04:23:47Z				EC:1.1.1.282|KEGG_REACTION:R06846|RHEA:18425		molecular_function											owl:Class	
GO:0072760	biolink:NamedThing	cellular response to GW 7647	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.	got7fsn_ti							mah	2012-11-09T11:46:28Z						biological_process											owl:Class	
GO:0018611	biolink:NamedThing	toluate dioxygenase activity	Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate.	got7fsn_ti												UM-BBD_enzymeID:e0190|EC:1.14.12.-		molecular_function											owl:Class	
GO:0106008	biolink:NamedThing	2-oxoglutaramate amidase activity	Catalysis of the reaction: 2-oxoglutaramate + H(2)O = 2-oxoglutarate + NH(3).	got7fsn_ti							hjd	2017-04-25T14:10:02Z				RHEA:32963|EC:3.5.1.111		molecular_function											owl:Class	
GO:0000484	biolink:NamedThing	cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0032544	biolink:NamedThing	plastid translation	The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.	got7fsn_ti	plastid protein anabolism|plastid protein synthesis|plastid protein translation|plastid protein biosynthesis|plastid protein formation													biological_process											owl:Class	
GO:0042437	biolink:NamedThing	indoleacetic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants.	got7fsn_ti	IAA catabolic process|indoleacetic acid catabolism|indole acetic acid catabolism|indole acetic acid catabolic process|indoleacetic acid breakdown|indoleacetic acid degradation													biological_process											owl:Class	
GO:0045230	biolink:NamedThing	capsule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi.	got7fsn_ti	capsule organisation|capsule organization and biogenesis													biological_process											owl:Class	
GO:0019867	biolink:NamedThing	outer membrane	The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.	got7fsn_ti														cellular_component											owl:Class	
GO:0061115	biolink:NamedThing	lung proximal/distal axis specification	The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.	got7fsn_ti							dph	2010-05-10T12:30:40Z						biological_process											owl:Class	
GO:0140111	biolink:NamedThing	[choline trimethylamine-lyase]-activating enzyme activity	Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14190					pg	2017-10-20T13:57:38Z				MetaCyc:RXN-16470		molecular_function											owl:Class	
GO:0035699	biolink:NamedThing	T-helper 17 cell extravasation	The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue.	got7fsn_ti							bf	2011-02-28T03:13:27Z						biological_process											owl:Class	
GO:0052674	biolink:NamedThing	ent-pimara-9(11),15-diene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate.	got7fsn_ti	ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-9(11),15-diene-forming] activity|PMD synthase activity											MetaCyc:RXN-9299|RHEA:25544|EC:4.2.3.31		molecular_function											owl:Class	
GO:0061137	biolink:NamedThing	bud dilation	The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch.	got7fsn_ti							dph	2010-05-20T07:54:42Z						biological_process											owl:Class	
GO:0050255	biolink:NamedThing	ribitol 2-dehydrogenase activity	Catalysis of the reaction: D-ribitol + NAD(+) = D-ribulose + H(+) + NADH.	got7fsn_ti	ribitol:NAD+ 2-oxidoreductase activity|ribitol dehydrogenase D (mutant enzyme with different properties)|adonitol dehydrogenase activity|ribitol dehydrogenase B (mutant enzyme with different properties)|ribitol dehydrogenase A (wild type)											EC:1.1.1.56|RHEA:20053|MetaCyc:RIBITOL-2-DEHYDROGENASE-RXN|KEGG_REACTION:R01895		molecular_function											owl:Class	
GO:0039679	biolink:NamedThing	viral occlusion body	A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host.	got7fsn_ti							bf	2013-09-26T14:17:10Z				VZ:1949		cellular_component											owl:Class	
GO:0140220	biolink:NamedThing	pathogen-containing vacuole	A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides.	got7fsn_ti	pathogen-containing compartment|pathogen inclusion	https://github.com/geneontology/go-ontology/issues/15580					pg	2018-04-20T06:02:14Z						cellular_component											owl:Class	
GO:0051736	biolink:NamedThing	polyribonucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA.	got7fsn_ti	ATP-dependent RNA 5'-hydroxyl-kinase activity|ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity|ATP-dependent polyribonucleotide kinase activity|ATP-dependent RNA kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity													molecular_function											owl:Class	
GO:0061099	biolink:NamedThing	negative regulation of protein tyrosine kinase activity	Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.	got7fsn_ti							dph	2010-04-26T02:34:53Z						biological_process											owl:Class	
GO:0050732	biolink:NamedThing	negative regulation of peptidyl-tyrosine phosphorylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.	got7fsn_ti	downregulation of peptidyl-tyrosine phosphorylation|down regulation of peptidyl-tyrosine phosphorylation|inhibition of peptidyl-tyrosine phosphorylation|down-regulation of peptidyl-tyrosine phosphorylation													biological_process											owl:Class	
GO:0032497	biolink:NamedThing	detection of lipopolysaccharide	The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.	got7fsn_ti	detection of LPS													biological_process											owl:Class	
GO:0050378	biolink:NamedThing	UDP-glucuronate 4-epimerase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate.	got7fsn_ti	UDP glucuronic epimerase activity|UDP-D-galacturonic acid 4-epimerase activity|UDP-galacturonate 4-epimerase activity|uridine diphospho-D-galacturonic acid|uridine diphosphoglucuronic epimerase activity|uridine diphosphoglucuronate epimerase activity|UDPglucuronate 4-epimerase activity											MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN|EC:5.1.3.6|KEGG_REACTION:R01385|MetaCyc:PWY-4861|RHEA:11404		molecular_function											owl:Class	
GO:0042912	biolink:NamedThing	colicin transmembrane transporter activity	Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.	got7fsn_ti														molecular_function											owl:Class	
GO:0035206	biolink:NamedThing	regulation of hemocyte proliferation	Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.	got7fsn_ti	regulation of arthropod blood cell proliferation													biological_process											owl:Class	
GO:0034926	biolink:NamedThing	pyrene-4,5-epoxide hydrolase activity	Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene.	got7fsn_ti												UM-BBD_reactionID:r0942		molecular_function											owl:Class	
GO:0006522	biolink:NamedThing	alanine metabolic process	The chemical reactions and pathways involving alanine, 2-aminopropanoic acid.	got7fsn_ti	alanine metabolism													biological_process											owl:Class	
GO:0080130	biolink:NamedThing	L-phenylalanine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate.	got7fsn_ti	L-phenylalanine:alpha-ketoglutarate aminotransferase activity				This reaction falls within the larger set of reactions associated with EC:2.6.1.57 and several other EC numbers (See BRENDA:http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.57).		dhl	2009-04-29T03:42:47Z				EC:2.6.1.57|MetaCyc:PHEAMINOTRANS-RXN|MetaCyc:RXN-10814|RHEA:25152|KEGG_REACTION:R00694		molecular_function											owl:Class	
GO:0052728	biolink:NamedThing	capsorubin synthase activity	Catalysis of the reaction: violaxanthin = capsorubin.	got7fsn_ti	violaxanthin-capsorubin isomerase (ketone-forming) activity|ketoxanthophyll synthase activity|CCS|capsanthin-capsorubin synthase activity						ai	2011-08-16T03:09:26Z				RHEA:21752|EC:5.3.99.8|MetaCyc:RXN-7946		molecular_function											owl:Class	
GO:0106350	biolink:NamedThing	octaprenyl pyrophosphate synthase activity	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate.	got7fsn_ti							hjd	2021-01-12T15:30:15Z				RHEA:27798|EC:2.5.1.90		molecular_function											owl:Class	
GO:0017183	biolink:NamedThing	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.	got7fsn_ti	peptidyl-diphthamide synthesis from peptidyl-histidine|peptidyl-diphthamide formation from peptidyl-histidine|peptidyl-diphthamide anabolism from peptidyl-histidine											RESID:AA0040		biological_process											owl:Class	
GO:0008948	biolink:NamedThing	oxaloacetate decarboxylase activity	Catalysis of the reaction: oxaloacetate = pyruvate + CO2.	got7fsn_ti	oxaloacetate beta-decarboxylase activity|oxaloacetate carboxy-lyase activity|oxalate beta-decarboxylase activity|oxaloacetate carboxy-lyase (pyruvate-forming)|oxalacetic acid decarboxylase activity											EC:1.1.1.40|KEGG_REACTION:R00217|EC:1.1.1.38|Reactome:R-HSA-9012016|RHEA:15641|EC:4.1.1.112|MetaCyc:OXALODECARB-RXN		molecular_function											owl:Class	
GO:0097655	biolink:NamedThing	serpin family protein binding	Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors.	got7fsn_ti	SERPIN family protein binding						pr	2014-09-24T16:19:31Z						molecular_function											owl:Class	
GO:0030627	biolink:NamedThing	pre-mRNA 5'-splice site binding	Binding to a pre-mRNA 5' splice site sequence.	got7fsn_ti	pre-mRNA 5' splice site binding													molecular_function											owl:Class	
GO:0090600	biolink:NamedThing	alpha-1,3-glucosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->3)-linked alpha-D-glucose residues with release of alpha-D-glucose.	got7fsn_ti							tb	2014-08-22T15:00:45Z						molecular_function											owl:Class	
GO:1900539	biolink:NamedThing	fumonisin metabolic process	The chemical reactions and pathways involving fumonisin.	got7fsn_ti	fumonisin metabolism						tb	2012-05-11T12:53:29Z						biological_process											owl:Class	
GO:0018545	biolink:NamedThing	NAD(P)H nitroreductase activity	Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative.	got7fsn_ti												UM-BBD_enzymeID:e0346		molecular_function											owl:Class	
GO:0047195	biolink:NamedThing	diacylglycerol-sterol O-acyltransferase activity	Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol.	got7fsn_ti	1,2-diacyl-sn-glycerol:sterol O-acyltransferase activity|1,2-diacyl-sn-glycerol:sterol acyl transferase activity											RHEA:13301|EC:2.3.1.73|MetaCyc:2.3.1.73-RXN		molecular_function											owl:Class	
GO:0045142	biolink:NamedThing	triplex DNA binding	Binding to a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination.	got7fsn_ti														molecular_function											owl:Class	
GO:0039666	biolink:NamedThing	virion attachment to host cell pilus	The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side.	got7fsn_ti	viral attachment to host cell pilus|pilus-mediated viral attachment to host cell|pilus-adsorption protein|pilus-mediated viral adsorption onto host cell						bf	2013-08-29T13:31:10Z				VZ:981		biological_process											owl:Class	
GO:0004422	biolink:NamedThing	hypoxanthine phosphoribosyltransferase activity	Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.	got7fsn_ti	HPRT|inosinate pyrophosphorylase activity|6-mercaptopurine phosphoribosyltransferase activity|inosinic pyrophosphorylase activity|IMP diphosphorylase activity|inosine 5'-phosphate pyrophosphorylase activity|IMP:diphosphate phospho-D-ribosyltransferase activity|IMP pyrophosphorylase activity|IMP-GMP pyrophosphorylase activity|purine-6-thiol phosphoribosyltransferase activity|hypoxanthine-guanine phosphoribosyltransferase activity|Transphosphoribosidase activity|6-hydroxypurine phosphoribosyltransferase activity|guanine-hypoxanthine phosphoribosyltransferase activity|HGPRTase activity|inosinic acid pyrophosphorylase activity											MetaCyc:HYPOXANPRIBOSYLTRAN-RXN|EC:2.4.2.8|KEGG_REACTION:R01132|Reactome:R-HSA-74215|RHEA:17973		molecular_function											owl:Class	
GO:0004464	biolink:NamedThing	leukotriene-C4 synthase activity	Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4).	got7fsn_ti	leukotriene A4:glutathione S-leukotrienyltransferase activity|LTC(4) synthetase activity|LTC4 synthetase activity|leukotriene C(4) synthetase activity|LTC4 synthase activity|leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)|LTC(4) synthase activity|(7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)|leukotriene A(4):glutathione S-leukotrienyltransferase activity|leukotriene C4 synthetase activity|(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)				Note that this function was EC:2.5.1.37.							RHEA:17617|MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN|EC:4.4.1.20|KEGG_REACTION:R03059|Reactome:R-HSA-266050		molecular_function											owl:Class	
GO:0071909	biolink:NamedThing	determination of stomach left/right asymmetry	Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.	got7fsn_ti							mah	2010-09-22T10:25:30Z						biological_process											owl:Class	
GO:0036309	biolink:NamedThing	protein localization to M-band	Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere.	got7fsn_ti	protein localization to M line|protein localization to M disc|cellular protein localization to M-band|protein localization to mesophragma						bf	2012-08-14T14:02:58Z						biological_process											owl:Class	
GO:0062076	biolink:NamedThing	acyl-CoA delta5-desaturase activity	Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta5-acyl-CoA + acceptor + 2 H2O.	got7fsn_ti	acyl-CoA D5-desaturase activity|acyl-CoA delta(5)-desaturase activity|acyl-CoA (8-3)-desaturase						dph	2018-09-24T15:33:59Z				RHEA:46424|EC:1.14.19.44		molecular_function											owl:Class	
GO:0098673	biolink:NamedThing	inhibition of host DNA replication by virus	Any process by which a virus inhibits DNA replication in its host cell.  Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication.	got7fsn_ti							dos	2017-01-17T15:58:15Z						biological_process											owl:Class	
GO:0016602	biolink:NamedThing	CCAAT-binding factor complex	A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.	got7fsn_ti	NF-Y transcription factor complex|nuclear transcription factor Y complex|CBF complex													cellular_component											owl:Class	
GO:0044104	biolink:NamedThing	2,5-dioxovalerate dehydrogenase (NAD+) activity	Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+.	got7fsn_ti	2,5-dioxopentanoate dehydrogenase (NAD+) activity|2,5-dioxopentanoate:NAD+ 5-oxidoreductase activity						jl	2009-07-09T04:15:14Z						molecular_function											owl:Class	
GO:0009921	biolink:NamedThing	auxin efflux carrier complex	The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0031687	biolink:NamedThing	A2A adenosine receptor binding	Binding to an A2A adenosine receptor.	got7fsn_ti	A2A adenosine receptor ligand													molecular_function											owl:Class	
GO:0042425	biolink:NamedThing	choline biosynthetic process	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	got7fsn_ti	choline anabolism|choline synthesis|choline biosynthesis|choline formation											MetaCyc:PWY-4762		biological_process											owl:Class	
GO:0097433	biolink:NamedThing	dense body	An electron dense body which may contain granules.	got7fsn_ti							pr	2012-11-22T15:34:04Z				NIF_Subcellular:sao730872736		cellular_component											owl:Class	
GO:0106362	biolink:NamedThing	protein-arginine N-acetylglucosaminyltransferase activity	Catalysis of the reaction: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP.	got7fsn_ti							hjd	2021-02-05T15:42:52Z				RHEA:66632		molecular_function											owl:Class	
GO:0018549	biolink:NamedThing	methanethiol oxidase activity	Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide.	got7fsn_ti	MT-oxidase activity|methanethiol:oxygen oxidoreductase activity|methyl mercaptan oxidase activity|(MM)-oxidase activity|methylmercaptan oxidase activity											UM-BBD_reactionID:r0209|EC:1.8.3.4|MetaCyc:METHANETHIOL-OXIDASE-RXN|RHEA:11812		molecular_function											owl:Class	
GO:0004644	biolink:NamedThing	phosphoribosylglycinamide formyltransferase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide.	got7fsn_ti	5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase activity|glycinamide ribonucleotide transformylase activity|GAR transformylase activity|GAR TFase activity|5'-phosphoribosylglycinamide transformylase activity|2-amino-N-ribosylacetamide 5'-phosphate transformylase activity|GAR formyltransferase activity|GART activity|10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase activity											Reactome:R-HSA-73813|MetaCyc:GART-RXN|EC:2.1.2.2|RHEA:15053		molecular_function											owl:Class	
GO:0003284	biolink:NamedThing	septum primum development	The progression of the septum primum over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-20T10:12:26Z						biological_process											owl:Class	
GO:0051044	biolink:NamedThing	positive regulation of membrane protein ectodomain proteolysis	Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.	got7fsn_ti	up-regulation of membrane protein ectodomain proteolysis|activation of membrane protein ectodomain proteolysis|stimulation of membrane protein ectodomain proteolysis|up regulation of membrane protein ectodomain proteolysis|upregulation of membrane protein ectodomain proteolysis													biological_process											owl:Class	
GO:0018182	biolink:NamedThing	protein-heme linkage via 3'-L-histidine	The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine).	got7fsn_ti	protein-haem linkage via 3'-L-histidine											RESID:AA0276		biological_process											owl:Class	
GO:0075131	biolink:NamedThing	induction by symbiont of host protein kinase-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host protein kinase-mediated signal transduction				Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075100".									biological_process											owl:Class	
GO:0070815	biolink:NamedThing	peptidyl-lysine 5-dioxygenase activity	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.	got7fsn_ti	lysyl hydroxylase activity|protein lysine hydroxylase activity|peptide-lysine 5-dioxygenase activity|lysine hydroxylase activity|peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity|lysine-2-oxoglutarate dioxygenase activity|peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity|lysine,2-oxoglutarate 5-dioxygenase activity						mah	2009-07-09T11:42:07Z						molecular_function											owl:Class	
GO:0060522	biolink:NamedThing	inductive mesenchymal to epithelial cell signaling	Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells.	got7fsn_ti	inductive mesenchymal to epithelial cell signalling													biological_process											owl:Class	
GO:0050470	biolink:NamedThing	trimethylamine dehydrogenase activity	Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein.	got7fsn_ti	TMADh activity|trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating)											MetaCyc:1.5.8.2-RXN|EC:1.5.8.2|RHEA:11864|UM-BBD_enzymeID:e0854		molecular_function											owl:Class	
GO:0043163	biolink:NamedThing	cell envelope organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present.	got7fsn_ti	cell envelope organization and biogenesis|cell envelope organisation													biological_process											owl:Class	
GO:0000705	biolink:NamedThing	achiasmate meiosis I	The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata.	got7fsn_ti	achiasmate meiosis I nuclear division													biological_process											owl:Class	
GO:0050368	biolink:NamedThing	tyrosine 2,3-aminomutase activity	Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate.	got7fsn_ti	L-tyrosine 2,3-aminomutase activity|tyrosine alpha,beta-mutase activity											MetaCyc:TYROSINE-23-AMINOMUTASE-RXN|KEGG_REACTION:R00739|EC:5.4.3.6|RHEA:15781		molecular_function											owl:Class	
GO:0050318	biolink:NamedThing	tannase activity	Catalysis of the reaction: digallate + H(2)O = 2 gallate + H(+).	got7fsn_ti	tannin acetylhydrolase activity|tannin acylhydrolase activity|tannase S											EC:3.1.1.20|MetaCyc:TANNASE-RXN|KEGG_REACTION:R00053|RHEA:16365		molecular_function											owl:Class	
GO:0033909	biolink:NamedThing	fucoidanase activity	Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate.	got7fsn_ti	poly(1,2-alpha-L-fucoside-4-sulfate) glycanohydrolase activity											EC:3.2.1.211|MetaCyc:RXN-20949		molecular_function											owl:Class	
GO:0034934	biolink:NamedThing	phenanthrene-4-carboxylate dioxygenase activity	Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate.	got7fsn_ti												UM-BBD_reactionID:r0939|EC:1.13.11.-		molecular_function											owl:Class	
GO:0031869	biolink:NamedThing	prostacyclin receptor binding	Binding to a prostacyclin receptor.	got7fsn_ti	prostanoid IP receptor binding|prostacyclin receptor ligand													molecular_function											owl:Class	
GO:0047116	biolink:NamedThing	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity	Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol.	got7fsn_ti	dihydrodihydroxybenzoate dehydrogenase activity|2-hydro-1,2-dihydroxybenzoate dehydrogenase activity|3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase activity|DHB dehydrogenase activity|cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase activity|DHBDH activity|(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)|cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase activity|3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase activity											RHEA:11560|EC:1.3.1.25|MetaCyc:1.3.1.25-RXN		molecular_function											owl:Class	
GO:0031815	biolink:NamedThing	P2Y5 nucleotide receptor binding	Binding to a P2Y5 nucleotide receptor.	got7fsn_ti	P2Y5 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0009825	biolink:NamedThing	multidimensional cell growth	The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes.	got7fsn_ti	cell growth in two dimensions|cell growth in three dimensions													biological_process											owl:Class	
GO:0072637	biolink:NamedThing	interleukin-32 production	The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-32 secretion|NK4 production|IL-32 production|interleukin-32 biosynthetic process|TAIF production|IL32 production						bc	2020-02-21T10:26:40Z			GO:0072638|GO:0150188			biological_process											owl:Class	
GO:0007608	biolink:NamedThing	sensory perception of smell	The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.	got7fsn_ti	olfaction|sense of smell|scent perception|smell perception											Wikipedia:Olfaction		biological_process											owl:Class	
GO:0030755	biolink:NamedThing	quercetin 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone.	got7fsn_ti	flavonol 3-O-methyltransferase activity|flavonoid 3-methyltransferase activity|S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase activity											RHEA:17673|EC:2.1.1.76|MetaCyc:QUERCETIN-3-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0033740	biolink:NamedThing	hydroxylamine oxidoreductase activity	Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor.	got7fsn_ti	hydroxylamine:acceptor oxidoreductase activity											RHEA:23232|EC:1.7.2.8|MetaCyc:1.7.99.8-RXN		molecular_function											owl:Class	
GO:0047251	biolink:NamedThing	thiohydroximate beta-D-glucosyltransferase activity	Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP.	got7fsn_ti	UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase activity|UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase activity|UDPG:thiohydroximate glucosyltransferase activity|thiohydroximate S-glucosyltransferase activity|uridine diphosphoglucose-thiohydroximate glucosyltransferase activity|N-hydroxythioamide S-beta-glucosyltransferase activity|desulfoglucosinolate-uridine diphosphate glucosyltransferase activity|thiohydroximate glucosyltransferase activity											MetaCyc:2.4.1.195-RXN|EC:2.4.1.195|RHEA:13757		molecular_function											owl:Class	
GO:0033970	biolink:NamedThing	N-malonylurea hydrolase activity	Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H(2)O = H(+) + malonate + urea.	got7fsn_ti	3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming) activity|ureidomalonase activity											KEGG_REACTION:R07629|MetaCyc:3.5.1.95-RXN|RHEA:17361|EC:3.5.1.95		molecular_function											owl:Class	
GO:0052597	biolink:NamedThing	diamine oxidase activity	Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide.	got7fsn_ti	diamine:oxygen oxidoreductase (deaminating) activity											EC:1.4.3.22|MetaCyc:RXN-9599		molecular_function											owl:Class	
GO:0035098	biolink:NamedThing	ESC/E(Z) complex	A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.	got7fsn_ti	PRC2 complex|Extra Sex Combs/Enhancer of Zeste complex													cellular_component											owl:Class	
GO:0010409	biolink:NamedThing	extensin metabolic process	The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated.	got7fsn_ti	extensin metabolism													biological_process											owl:Class	
GO:0032621	biolink:NamedThing	interleukin-18 production	The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-18 production|interleukin-18 biosynthetic process|IL1F4 production|IGIF production|interleukin-18 secretion										GO:0072616|GO:0042241			biological_process											owl:Class	
GO:0034732	biolink:NamedThing	transcription factor TFIIIB-alpha complex	A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters.	got7fsn_ti														cellular_component											owl:Class	
GO:0000126	biolink:NamedThing	transcription factor TFIIIB complex	A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF.	got7fsn_ti														cellular_component											owl:Class	
GO:0035135	biolink:NamedThing	post-embryonic anal fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.	got7fsn_ti														biological_process											owl:Class	
GO:0070936	biolink:NamedThing	protein K48-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.	got7fsn_ti	protein K48-linked polyubiquitination						mah	2009-09-21T03:25:27Z						biological_process											owl:Class	
GO:1902774	biolink:NamedThing	late endosome to lysosome transport	The directed movement of substances from late endosome to lysosome.	got7fsn_ti	prevacuolar compartment to lysosome transport				an example of this is snapin in mouse (Q9Z266) in PMID:20920792 inferred from mutant phenotype		pad	2014-03-17T16:32:36Z						biological_process											owl:Class	
GO:0004034	biolink:NamedThing	aldose 1-epimerase activity	Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.	got7fsn_ti	mutarotase activity|aldose mutarotase activity											EC:5.1.3.3|MetaCyc:ALDOSE-1-EPIMERASE-RXN|RHEA:10264		molecular_function											owl:Class	
GO:0016161	biolink:NamedThing	beta-amylase activity	Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.	got7fsn_ti	beta amylase activity|glycogenase activity|1,4-alpha-D-glucan maltohydrolase activity|saccharogen amylase activity											MetaCyc:RXN-1827|EC:3.2.1.2|MetaCyc:RXN-12279		molecular_function											owl:Class	
GO:0045007	biolink:NamedThing	depurination	The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar.	got7fsn_ti												Wikipedia:Depurination		biological_process											owl:Class	
GO:0097296	biolink:NamedThing	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway.	got7fsn_ti	activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|activation of initiator caspase activity				Components of the DISC (death-inducing signaling complex) may be annotated to this term. These include ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer), and signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Note that GO:0097296 should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the apoptotic signaling pathway (also known as an initiator caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process.		pr	2012-05-02T03:19:35Z						biological_process											owl:Class	
GO:2001269	biolink:NamedThing	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.	got7fsn_ti	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|positive regulation of initiator caspase activity						pr	2011-12-13T07:56:26Z						biological_process											owl:Class	
GO:0018915	biolink:NamedThing	ethylbenzene metabolic process	The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels.	got7fsn_ti	ethylbenzene metabolism											UM-BBD_pathwayID:ethb2		biological_process											owl:Class	
GO:0072035	biolink:NamedThing	pre-tubular aggregate formation	The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.	got7fsn_ti	mesenchymal cell condensation involved in renal vesicle formation|nephron epithelium formation						mah	2010-01-25T03:03:10Z						biological_process											owl:Class	
GO:0097628	biolink:NamedThing	distal tip cell migration	The orderly movement of a distal tip cell.	got7fsn_ti							pr	2014-08-20T16:06:53Z						biological_process											owl:Class	
GO:0019123	biolink:NamedThing	peptidyl-methionine racemization	The racemization of peptidyl-methionine.	got7fsn_ti											GO:0018087|GO:0018369	RESID:AA0193		biological_process											owl:Class	
GO:0046539	biolink:NamedThing	histamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	histamine 1-methyltransferase activity|histamine methyltransferase activity|S-adenosylmethionine-histamine N-methyltransferase activity|imidazolemethyltransferase activity|histamine-methylating enzyme|S-adenosyl-L-methionine:histamine N-tele-methyltransferase activity											RHEA:19301|EC:2.1.1.8|Reactome:R-HSA-175993|KEGG_REACTION:R02155|MetaCyc:HISTAMINE-N-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0004821	biolink:NamedThing	histidine-tRNA ligase activity	Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).	got7fsn_ti	histidyl-transfer ribonucleate synthetase activity|L-histidine:tRNAHis ligase (AMP-forming)|histidine translase activity|histidyl-tRNA synthetase activity											RHEA:17313|MetaCyc:HISTIDINE--TRNA-LIGASE-RXN|EC:6.1.1.21|Reactome:R-HSA-380234|Reactome:R-HSA-379844		molecular_function											owl:Class	
GO:0047448	biolink:NamedThing	5-dehydro-4-deoxyglucarate dehydratase activity	Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO(2) + H(2)O.	got7fsn_ti	5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating)|deoxyketoglucarate dehydratase activity|5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)|D-4-deoxy-5-ketoglucarate hydro-lyase activity|5-keto-4-deoxy-glucarate dehydratase activity											RHEA:24608|KEGG_REACTION:R02279|EC:4.2.1.41|MetaCyc:4.2.1.41-RXN		molecular_function											owl:Class	
GO:0061749	biolink:NamedThing	forked DNA-dependent helicase activity	Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis.	got7fsn_ti							dph	2015-11-11T13:10:51Z						molecular_function											owl:Class	
GO:0071043	biolink:NamedThing	CUT metabolic process	The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome.	got7fsn_ti							krc	2009-07-29T02:31:31Z						biological_process											owl:Class	
GO:0018143	biolink:NamedThing	nucleic acid-protein covalent cross-linking	The formation of a covalent cross-link between a nucleic acid and a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0055049	biolink:NamedThing	astral spindle assembly	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the presence of centrosomes.	got7fsn_ti														biological_process											owl:Class	
GO:0036164	biolink:NamedThing	cell-abiotic substrate adhesion	The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.	got7fsn_ti	cell-abiotic surface adhesion						bf	2012-03-27T11:18:33Z						biological_process											owl:Class	
GO:0061031	biolink:NamedThing	endodermal digestive tract morphogenesis	The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.	got7fsn_ti							dph	2010-02-09T09:46:43Z						biological_process											owl:Class	
GO:0150023	biolink:NamedThing	apical dendrite arborization	The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches.	got7fsn_ti							bc	2017-12-22T11:56:05Z						biological_process											owl:Class	
GO:0150021	biolink:NamedThing	apical dendrite morphogenesis	The process in which the anatomical structures of an apical dendrite are generated and organized.	got7fsn_ti							bc	2017-12-22T11:50:00Z						biological_process											owl:Class	
GO:0050052	biolink:NamedThing	leukotriene-E4 20-monooxygenase activity	Catalysis of the reaction: H(+) + leukotriene E(4) + NADPH + O(2) = 20-hydroxy-leukotriene E(4) + H(2)O + NADP(+).	got7fsn_ti	leukotriene-E4 w-hydroxylase activity|leukotriene-E(4) omega-hydroxylase activity|leukotriene-E4 omega-hydroxylase activity|(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)											EC:1.14.13.34|MetaCyc:LEUKOTRIENE-E4-20-MONOOXYGENASE-RXN|KEGG_REACTION:R04256|RHEA:24120		molecular_function											owl:Class	
GO:0043734	biolink:NamedThing	DNA-N1-methyladenine dioxygenase activity	Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde.	got7fsn_ti	alpha-ketoglutarate-dependent dioxygenase|AlkB											Reactome:R-HSA-112118|Reactome:R-HSA-112123		molecular_function											owl:Class	
GO:0009223	biolink:NamedThing	pyrimidine deoxyribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine deoxyribonucleotide breakdown|pyrimidine deoxyribonucleotide degradation|pyrimidine deoxyribonucleotide catabolism													biological_process											owl:Class	
GO:0001080	biolink:NamedThing	nitrogen catabolite activation of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter by nitrogen catabolites						krc	2010-10-27T03:32:34Z						biological_process											owl:Class	
GO:0004940	biolink:NamedThing	beta1-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors.	got7fsn_ti	beta1 adrenoceptor													molecular_function											owl:Class	
GO:0015039	biolink:NamedThing	NADPH-adrenodoxin reductase activity	Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+.	got7fsn_ti	NADPH:adrenodoxin oxidoreductase activity|adrenodoxin-type ferredoxin reductase activity|adrenodoxin reductase activity				Note that this term specifically refers to the reaction proceeding in the direction shown; under physiological conditions adrenodoxin reduction by adrenodoxin reductase is coupled with electron transfer from AdR to P450, which catalyzes an irreversible monooxygenation reaction. This term should therefore be used to annotate gene products that catalyze the reduction of oxidized adrenodoxin; also consider annotating to the molecular function term 'ferredoxin-NADP+ reductase activity ; GO:0004324'.							MetaCyc:RXN-13685|EC:1.18.1.6|RHEA:42312		molecular_function											owl:Class	
GO:0034415	biolink:NamedThing	tRNA 3'-trailer cleavage, exonucleolytic	Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.	got7fsn_ti	tRNA 3'-end cleavage, exonucleolytic|exonucleolytic tRNA 3'-trailer cleavage|exonucleolytic tRNA 3'-end cleavage													biological_process											owl:Class	
GO:0043261	biolink:NamedThing	laminin-12 complex	A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains.	got7fsn_ti	laminin-213 complex													cellular_component											owl:Class	
GO:1905369	biolink:NamedThing	endopeptidase complex	A protein complex which is capable of endopeptidase activity.	got7fsn_ti					An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay).		bhm	2016-08-16T12:52:16Z						cellular_component											owl:Class	
GO:0019651	biolink:NamedThing	citrate catabolic process to diacetyl	The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP.	got7fsn_ti	citrate fermentation to diacetyl|diacetyl fermentation													biological_process											owl:Class	
GO:0009091	biolink:NamedThing	homoserine catabolic process	The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid.	got7fsn_ti	homoserine degradation|homoserine breakdown|homoserine catabolism											MetaCyc:HOMOCYSDEGR-PWY		biological_process											owl:Class	
GO:0102635	biolink:NamedThing	11-deoxycorticosterone reductase activity	Catalysis of the reaction: 11-deoxycorticosterone + NADH + H+ <=> 4-pregnen-20,21-diol-3-one + NAD.	got7fsn_ti												RHEA:47716|MetaCyc:RXN-15607		molecular_function											owl:Class	
GO:0102323	biolink:NamedThing	2-isopropylphenol monooxygenase activity	Catalysis of the reaction: 2-isopropylphenol + O2 + NADH + H+ = 3-isopropylcatechol + H2O + NAD.	got7fsn_ti												MetaCyc:RXN-13152|RHEA:63520		molecular_function											owl:Class	
GO:0038203	biolink:NamedThing	TORC2 signaling	A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.	got7fsn_ti	TORC2 signal transduction						bf	2013-12-09T14:43:29Z						biological_process											owl:Class	
GO:0009024	biolink:NamedThing	tagatose-6-phosphate kinase activity	Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.	got7fsn_ti	phosphotagatokinase activity|ATP:D-tagatose-6-phosphate 1-phosphotransferase activity											RHEA:12420|MetaCyc:TAGAKIN-RXN|EC:2.7.1.144		molecular_function											owl:Class	
GO:0050420	biolink:NamedThing	maltose synthase activity	Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate.	got7fsn_ti	alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating)											MetaCyc:MALTOSE-SYNTHASE-RXN|EC:2.4.1.139|RHEA:22320		molecular_function											owl:Class	
GO:0030412	biolink:NamedThing	formimidoyltetrahydrofolate cyclodeaminase activity	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+).	got7fsn_ti	formiminotetrahydrofolate cyclodeaminase activity|5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)|5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)				Note that cyclodeaminases are lyases according to EC, whereas deaminases are hydrolases.							MetaCyc:4.3.1.4-RXN|RHEA:22736|EC:4.3.1.4|Reactome:R-HSA-70920|KEGG_REACTION:R02302		molecular_function											owl:Class	
GO:0038003	biolink:NamedThing	G protein-coupled opioid receptor signaling pathway	The series of molecular signals generated as a consequence of an opioid receptor binding to one of its physiological ligands.	got7fsn_ti	opioid receptor signalling pathway|opioid receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/21110					bf	2011-03-03T02:00:02Z				Wikipedia:Opioid_receptor		biological_process											owl:Class	
GO:0036076	biolink:NamedThing	ligamentous ossification	Ossification wherein bone tissue forms within ligamentous tissue.	got7fsn_ti					Ligamentous ossification may occur via replacement ossification or metaplastic ossification or both in any one instance.		bf	2011-12-19T01:57:08Z						biological_process											owl:Class	
GO:0002419	biolink:NamedThing	T cell mediated cytotoxicity directed against tumor cell target	The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.	got7fsn_ti	T-cell mediated cytotoxicity directed against tumor cell target|T lymphocyte mediated cytotoxicity directed against tumor cell target|T-lymphocyte mediated cytotoxicity directed against tumor cell target				Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.									biological_process											owl:Class	
GO:0047586	biolink:NamedThing	5'-acylphosphoadenosine hydrolase activity	Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate.	got7fsn_ti	5'-acylphosphoadenosine acylhydrolase activity|5-phosphoadenosine hydrolase activity											MetaCyc:5-ACYLPHOSPHOADENOSINE-HYDROLASE-RXN|EC:3.6.1.20|RHEA:16837		molecular_function											owl:Class	
GO:0090427	biolink:NamedThing	activation of meiosis	Any process that starts the inactive process of meiosis.	got7fsn_ti							tb	2012-05-04T09:50:19Z						biological_process											owl:Class	
GO:0016206	biolink:NamedThing	catechol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol.	got7fsn_ti	catecholamine O-methyltransferase activity|catechol methyltransferase activity|COMT I|S-adenosyl-L-methionine:catechol O-methyltransferase activity|COMT II|S-COMT (soluble form of catechol-O-methyltransferase)|MB-COMT (membrane-bound form of catechol-O-methyltransferase)											Reactome:R-HSA-8955010|MetaCyc:CATECHOL-O-METHYLTRANSFERASE-RXN|EC:2.1.1.6|Reactome:R-HSA-175983		molecular_function											owl:Class	
GO:0036285	biolink:NamedThing	SAGA complex assembly	The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof.	got7fsn_ti	SAGA complex formation						bf	2012-07-16T10:30:00Z						biological_process											owl:Class	
GO:0102877	biolink:NamedThing	alpha-copaene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-copaene + diphosphoric acid.	got7fsn_ti												EC:4.2.3.133|RHEA:33991|MetaCyc:RXN-8416		molecular_function											owl:Class	
GO:0071303	biolink:NamedThing	cellular response to vitamin B3	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.	got7fsn_ti	cellular response to niacin|cellular response to nicotinamide						mah	2009-12-10T04:35:04Z						biological_process											owl:Class	
GO:0071295	biolink:NamedThing	cellular response to vitamin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.	got7fsn_ti							mah	2009-12-10T04:27:24Z						biological_process											owl:Class	
GO:1990232	biolink:NamedThing	phosphomannomutase complex	A protein complex capable of phosphomannomutase activity.	got7fsn_ti	PMM-2 complex|PMM-2 dimer|PMM-1 complex|PMM-1 dimer						bhm	2013-11-12T13:05:54Z						cellular_component											owl:Class	
GO:0102340	biolink:NamedThing	3-oxo-behenoyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA(4-) + NADP(3-) <=> 3-oxodocosanoyl-CoA + NADPH + H+.	got7fsn_ti												EC:1.1.1.330|MetaCyc:RXN-13299		molecular_function											owl:Class	
GO:0032448	biolink:NamedThing	DNA hairpin binding	Binding to a DNA region containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.	got7fsn_ti														molecular_function											owl:Class	
GO:0043776	biolink:NamedThing	cobalt-precorrin-6B C5-methyltransferase activity	Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7.	got7fsn_ti	cobalt-precorrin 6B C5-methyltransferase activity|precorrin-6Y C5,15-methyltransferase (decarboxylating)|precorrin-6 methyltransferase activity|precorrin-6Y methylase											RHEA:36067|MetaCyc:RXN-8766		molecular_function											owl:Class	
GO:1901270	biolink:NamedThing	lipooligosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide.	got7fsn_ti	lipooligosaccharide degradation|lipooligosaccharide breakdown|lipooligosaccharide catabolism						yaf	2012-08-17T14:31:48Z						biological_process											owl:Class	
GO:0009313	biolink:NamedThing	oligosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	got7fsn_ti	oligosaccharide degradation|oligosaccharide breakdown|oligosaccharide catabolism|multicellular organismal oligosaccharide catabolic process										GO:0051689			biological_process											owl:Class	
GO:0072190	biolink:NamedThing	ureter urothelium development	The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.	got7fsn_ti	ureter epithelium development						mah	2010-03-01T01:46:31Z						biological_process											owl:Class	
GO:0098988	biolink:NamedThing	G protein-coupled glutamate receptor activity	Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.	got7fsn_ti	G-protein coupled glutamate receptor activity													molecular_function											owl:Class	
GO:0046942	biolink:NamedThing	carboxylic acid transport	The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).	got7fsn_ti														biological_process											owl:Class	
GO:0014869	biolink:NamedThing	detection of muscle inactivity	The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0014870	biolink:NamedThing	response to muscle inactivity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0047039	biolink:NamedThing	tetrahydroxynaphthalene reductase activity	Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol.	got7fsn_ti	T4HN reductase activity|scytalone:NADP+ delta5-oxidoreductase activity											MetaCyc:1.1.1.252-RXN|EC:1.1.1.252|RHEA:21908		molecular_function											owl:Class	
GO:0099555	biolink:NamedThing	trans-synaptic signaling by nitric oxide, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0047383	biolink:NamedThing	guanidinodeoxy-scyllo-inositol-4-phosphatase activity	Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H(2)O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate.	got7fsn_ti	1-guanidino-scyllo-inositol 4-phosphatase activity|1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase activity|1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase activity											MetaCyc:3.1.3.40-RXN|RHEA:15777|KEGG_REACTION:R03496|EC:3.1.3.40		molecular_function											owl:Class	
GO:0070911	biolink:NamedThing	global genome nucleotide-excision repair	The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.	got7fsn_ti	global genome NER|GG-NER|global genomic repair|global genomic nucleotide-excision repair|GGR						mah	2009-09-09T03:13:11Z						biological_process											owl:Class	
GO:0004439	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.	got7fsn_ti	PtdIns(4,5)P2 5-phosphatase activity|phosphatidylinositol-bisphosphatase activity|triphosphoinositide phosphatase activity|PI(4,5)P2 5-phosphatase activity|phosphatidylinositol 4,5-bisphosphate phosphatase activity|triphosphoinositide phosphomonoesterase activity|PtdIns(4,5)P(2) 5-phosphatase activity|phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase activity										GO:0001668	Reactome:R-HSA-1675824|EC:3.1.3.36|Reactome:R-HSA-8868648|MetaCyc:PHOSPHATIDYLINOSITOL-BISPHOSPHATASE-RXN|KEGG_REACTION:R04404|RHEA:22764|Reactome:R-HSA-1676177		molecular_function											owl:Class	
GO:0019458	biolink:NamedThing	methionine catabolic process via 2-oxobutanoate	The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate.	got7fsn_ti	methionine degradation via 2-oxobutanoate|methionine breakdown via 2-oxobutanoate											MetaCyc:PWY-701		biological_process											owl:Class	
GO:0016871	biolink:NamedThing	cycloartenol synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.	got7fsn_ti	oxidosqualene:cycloartenol cyclase activity|2,3-epoxysqualene--cycloartenol cyclase activity|2,3-oxidosqualene-cycloartenol cyclase activity|2,3-epoxysqualene cycloartenol-cyclase activity|squalene-2,3-epoxide-cycloartenol cyclase activity|(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)											EC:5.4.99.8|KEGG_REACTION:R03200|MetaCyc:CYCLOARTENOL-SYNTHASE-RXN|RHEA:21308		molecular_function											owl:Class	
GO:0045439	biolink:NamedThing	isopenicillin-N epimerase activity	Catalysis of the reaction: isopenicillin N = penicillin N.	got7fsn_ti	isopenicillin N epimerase activity|penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity											RHEA:20033|MetaCyc:5.1.1.17-RXN|KEGG_REACTION:R04147|EC:5.1.1.17		molecular_function											owl:Class	
GO:0140376	biolink:NamedThing	innate immune receptor activity	Receiving a signal and transmitting it in a cell to initiate an innate immune response.	got7fsn_ti							pg	2019-10-18T14:21:28Z						molecular_function											owl:Class	
GO:0017113	biolink:NamedThing	dihydropyrimidine dehydrogenase (NADP+) activity	Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+.	got7fsn_ti	DPD|5,6-dihydrouracil:NADP+ 5-oxidoreductase activity|4,5-dihydrothymine: oxidoreductase activity|dihydrothymine dehydrogenase activity|hydropyrimidine dehydrogenase activity|dihydrouracil dehydrogenase (NADP+) activity|DHU dehydrogenase activity|dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)|dihydropyrimidine dehydrogenase activity|DHPDH|dihydrouracil dehydrogenase (NADP)											EC:1.3.1.2|RHEA:18093|Reactome:R-HSA-73616|Reactome:R-HSA-73585|MetaCyc:1.3.1.2-RXN		molecular_function											owl:Class	
GO:0018015	biolink:NamedThing	N-terminal peptidyl-phenylalanine methylation	The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine.	got7fsn_ti												RESID:AA0065		biological_process											owl:Class	
GO:0036178	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to neutral pH	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.	got7fsn_ti							bf	2012-03-29T01:43:47Z						biological_process											owl:Class	
GO:0047379	biolink:NamedThing	ADP-dependent short-chain-acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA.	got7fsn_ti	ADP-dependent short-chain acyl coenzyme A hydrolase activity|ADP-dependent propionyl-CoA thioesterase activity|ADP-dependent short-chain acyl-CoA hydrolase activity|ADP-dependent short-chain acyl-CoA thioesterase activity|ADP-dependent-short-chain-acyl-CoA hydrolase activity|ADP-dependent propionyl-CoA hydrolase activity|ADP-dependent propionyl coenzyme A hydrolase activity											MetaCyc:3.1.2.18-RXN|EC:3.1.2.18		molecular_function											owl:Class	
GO:0030788	biolink:NamedThing	precorrin-2 C20-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H(+) + precorrin-3A.	got7fsn_ti	S-adenosyl-L-methionine--precorrin-2 methyltransferase activity|S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase activity											RHEA:16841|MetaCyc:2.1.1.130-RXN|EC:2.1.1.130|KEGG_REACTION:R03948		molecular_function											owl:Class	
GO:0004138	biolink:NamedThing	deoxyguanosine kinase activity	Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+).	got7fsn_ti	deoxyguanosine kinase (phosphorylating)|ATP:deoxyguanosine 5'-phosphotransferase activity|2'-deoxyguanosine kinase activity|(dihydroxypropoxymethyl)guanine kinase activity|NTP-deoxyguanosine 5'-phosphotransferase activity											KEGG_REACTION:R01967|RHEA:19201|EC:2.7.1.113|MetaCyc:DEOXYGUANOSINE-KINASE-RXN		molecular_function											owl:Class	
GO:0009249	biolink:NamedThing	protein lipoylation	The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.	got7fsn_ti	protein-lipoic acid cofactor linkage|peptidyl-lysine lipoylation										GO:0018055			biological_process											owl:Class	
GO:0106304	biolink:NamedThing	mannogen biosynthetic process	The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.	got7fsn_ti	beta-1,2-mannan biosynthetic process|mannogen biosynthesis|mannogen anabolism|mannogen synthesis|mannogen formation						hjd	2020-09-09T13:52:26Z						biological_process											owl:Class	
GO:0031848	biolink:NamedThing	protection from non-homologous end joining at telomere	A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.	got7fsn_ti	protection from NHEJ-mediated telomere fusion													biological_process											owl:Class	
GO:0043247	biolink:NamedThing	telomere maintenance in response to DNA damage	Any process that occur in response to the presence of critically short or damaged telomeres.	got7fsn_ti	DNA damage response, telomere maintenance													biological_process											owl:Class	
GO:0062176	biolink:NamedThing	R-loop disassembly	A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.	got7fsn_ti							dph	2019-11-19T12:47:04Z						biological_process											owl:Class	
GO:0003117	biolink:NamedThing	regulation of vasoconstriction by circulating norepinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.	got7fsn_ti	regulation of vasoconstriction by circulating noradrenaline													biological_process											owl:Class	
GO:0003116	biolink:NamedThing	regulation of vasoconstriction by norepinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings.	got7fsn_ti														biological_process											owl:Class	
GO:0035212	biolink:NamedThing	cell competition in a multicellular organism	Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.	got7fsn_ti														biological_process											owl:Class	
GO:0005523	biolink:NamedThing	tropomyosin binding	Binding to tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.	got7fsn_ti														molecular_function											owl:Class	
GO:0071082	biolink:NamedThing	alpha9-beta1 integrin-tenascin complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.	got7fsn_ti	ITGA9-ITGB1-TNC complex						mah	2009-11-06T04:43:58Z						cellular_component											owl:Class	
GO:0045175	biolink:NamedThing	basal protein localization	Any process in which a protein is transported to, or maintained in, basal regions of the cell.	got7fsn_ti	establishment and maintenance of protein localization in basal part of cell|basal protein localisation|establishment and maintenance of basal protein localization													biological_process											owl:Class	
GO:0098806	biolink:NamedThing	deadenylation involved in gene silencing by miRNA	Shortening of the poly(A) tail of a nuclear-transcribed mRNA following miRNA binding to mRNA, resulting in destabilization of the mRNA and a reduction in the efficiency of its translation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20568												biological_process											owl:Class	
GO:0044305	biolink:NamedThing	calyx of Held	The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.	got7fsn_ti							jl	2010-02-05T02:33:20Z				NIF_Subcellular:sao1684283879		cellular_component											owl:Class	
GO:0080059	biolink:NamedThing	flavonol 3-O-arabinosyltransferase activity	Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside.	got7fsn_ti							dhl	2009-04-13T02:55:11Z						molecular_function											owl:Class	
GO:0090547	biolink:NamedThing	response to low humidity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere.	got7fsn_ti							tb	2013-04-17T13:46:28Z						biological_process											owl:Class	
GO:0046978	biolink:NamedThing	TAP1 binding	Binding to the TAP1 subunit of TAP (transporter associated with antigen processing) protein.	got7fsn_ti														molecular_function											owl:Class	
GO:1903491	biolink:NamedThing	response to simvastatin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		hp	2014-09-25T10:58:06Z						biological_process											owl:Class	
GO:0036273	biolink:NamedThing	response to statin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.	got7fsn_ti	response to HMG-CoA reductase inhibitor|response to hydroxymethylglutaryl-CoA reductase inhibitor				Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T01:54:01Z						biological_process											owl:Class	
GO:0019481	biolink:NamedThing	L-alanine catabolic process, by transamination	The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination.	got7fsn_ti	L-alanine degradation, by transamination|L-alanine breakdown, by transamination											MetaCyc:ALANINE-DEG3-PWY		biological_process											owl:Class	
GO:0019248	biolink:NamedThing	D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde	The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde.	got7fsn_ti	D-lactate synthesis from methylglyoxal via (R)-lactaldehyde|D-lactate formation from methylglyoxal via (R)-lactaldehyde|D-lactate anabolism from methylglyoxal via (R)-lactaldehyde											MetaCyc:MGLDLCTANA-PWY		biological_process											owl:Class	
GO:0051443	biolink:NamedThing	positive regulation of ubiquitin-protein transferase activity	Any process that activates, maintains or increases the rate of ubiquitin transferase activity.	got7fsn_ti	ubiquitin transferase activator|up regulation of ubiquitin ligase activity|anaphase-promoting complex activator|positive regulation of ubiquitin transferase activity|APC activator|stimulation of ubiquitin transferase activity|APC activation|SCF complex activator|upregulation of ubiquitin transferase activity|anaphase promoting complex activator|up-regulation of ubiquitin transferase activity|activation of ubiquitin transferase activity													biological_process											owl:Class	
GO:0031398	biolink:NamedThing	positive regulation of protein ubiquitination	Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.	got7fsn_ti	upregulation of protein ubiquitination|up-regulation of protein ubiquitination|activation of protein ubiquitination|up regulation of protein ubiquitination|stimulation of protein ubiquitination													biological_process											owl:Class	
GO:0043827	biolink:NamedThing	tRNA (adenine-57, 58-N(1)-) methyltransferase activity	Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA.	got7fsn_ti	TrmI|tRNA (m1A) MTase|tRNA (adenine-57, 58-N1-) methyltransferase activity|tRNA (adenine-57, 58 N1-) methyltransferase activity													molecular_function											owl:Class	
GO:0050541	biolink:NamedThing	beta,beta-carotene-9',10'-dioxygenase activity	Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone.	got7fsn_ti	b,b-carotene-9',10'-dioxygenase activity													molecular_function											owl:Class	
GO:0031727	biolink:NamedThing	CCR2 chemokine receptor binding	Binding to a CCR2 chemokine receptor.	got7fsn_ti	CCR2 chemokine receptor ligand|monocyte chemoattractant protein 1 receptor binding													molecular_function											owl:Class	
GO:0070769	biolink:NamedThing	alphaIIb-beta3 integrin-CIB complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.	got7fsn_ti	ITGA2B-ITGB3-CIB1 complex						mah	2009-06-29T05:20:01Z						cellular_component											owl:Class	
GO:0070017	biolink:NamedThing	alphav-beta3 integrin-thrombospondin complex	A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin.	got7fsn_ti	ITGAV-ITGB3-THBS1 complex													cellular_component											owl:Class	
GO:0030448	biolink:NamedThing	hyphal growth	Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.	got7fsn_ti	formation of symbiont invasive hypha in host|symbiont invasive hypha formation within host|formation of symbiont invasive hypha within host|formation of symbiont invasive hypha within host during symbiotic interaction|invasive hyphal growth	https://github.com/geneontology/go-ontology/issues/19013									GO:0075061			biological_process											owl:Class	
GO:0009588	biolink:NamedThing	UV-A, blue light phototransduction	The sequence of reactions within a cell required to convert absorbed photons from UV-A or blue light into a molecular signal; the UV-A, blue light range is defined as having a wavelength within the range of 315 to 400 nm.	got7fsn_ti	violet-sensitive opsin|short-wave-sensitive opsin|blue-sensitive opsin													biological_process											owl:Class	
GO:0008838	biolink:NamedThing	diaminopropionate ammonia-lyase activity	Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3.	got7fsn_ti	2,3-diaminopropionate ammonia-lyase (adding H2O; pyruvate-forming)|diaminopropionatase activity|2,3-diaminopropionate ammonia-lyase activity|alpha,beta-diaminopropionate ammonia-lyase activity											RHEA:22084|MetaCyc:4.3.1.15-RXN|EC:4.3.1.15		molecular_function											owl:Class	
GO:0018062	biolink:NamedThing	peptidyl-tryptophan succinylation	The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan.	got7fsn_ti												RESID:AA0130		biological_process											owl:Class	
GO:0036336	biolink:NamedThing	dendritic cell migration	The movement of a dendritic cell within or between different tissues and organs of the body.	got7fsn_ti							bf	2012-09-05T10:24:46Z						biological_process											owl:Class	
GO:0051071	biolink:NamedThing	4,6-pyruvylated galactose residue metabolic process	The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.	got7fsn_ti	4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolism|PvGal metabolic process|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolic process|PvGal metabolism|4,6-pyruvylated galactose residue metabolism													biological_process											owl:Class	
GO:0102539	biolink:NamedThing	UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-14769		molecular_function											owl:Class	
GO:0034701	biolink:NamedThing	tripeptidase activity	Catalysis of the hydrolysis of a tripeptide.	got7fsn_ti												MetaCyc:3.4.11.4-RXN|EC:3.4.13.-		molecular_function											owl:Class	
GO:1990346	biolink:NamedThing	BID-BCL-xl complex	A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							bhm	2014-03-25T00:18:41Z						cellular_component											owl:Class	
GO:0072639	biolink:NamedThing	interleukin-33 production	The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-33 production|interleukin-33 secretion|C9orf26 production|NF-HEV production|interleukin-33 biosynthetic process|IL33 production|IL1F11 production										GO:0072640|GO:0150126			biological_process											owl:Class	
GO:0102515	biolink:NamedThing	pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + ferulate + H+.	got7fsn_ti												MetaCyc:RXN-14447		molecular_function											owl:Class	
GO:0102212	biolink:NamedThing	unsaturated chondroitin disaccharide hydrolase activity	Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate.	got7fsn_ti												RHEA:31647|EC:3.2.1.180|MetaCyc:RXN-12177		molecular_function											owl:Class	
GO:0005163	biolink:NamedThing	nerve growth factor receptor binding	Binding to a nerve growth factor receptor.	got7fsn_ti	nerve growth factor receptor ligand|NGF receptor binding|neurotrophin													molecular_function											owl:Class	
GO:0050621	biolink:NamedThing	tryptophan alpha,beta-oxidase activity	Catalysis of the reaction: L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2) + H(+).	got7fsn_ti	L-tryptophan alpha,beta-dehydrogenase activity|tryptophan a,b-oxidase activity|L-tryptophan:oxygen alpha,beta-oxidoreductase activity|L-tryptophan 2',3'-oxidase activity				Note that this was EC:1.4.3.17.							MetaCyc:1.4.3.17-RXN|KEGG_REACTION:R05317|EC:1.3.3.10|RHEA:19901		molecular_function											owl:Class	
GO:0005052	biolink:NamedThing	peroxisome matrix targeting signal-1 binding	Binding to a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L.	got7fsn_ti	PEX5|PTS1 receptor|peroxisome targeting signal-1 binding|peroxisomal targeting signal 1 (PTS1) binding|peroxisome targeting signal-1 receptor|PTS1 binding													molecular_function											owl:Class	
GO:0018830	biolink:NamedThing	gamma-hexachlorocyclohexane dehydrochlorinase activity	Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene.	got7fsn_ti												UM-BBD_enzymeID:e0359|EC:4.5.1.-		molecular_function											owl:Class	
GO:0140621	biolink:NamedThing	type I pilus	A short filamentous structure on the surface of a bacterial cell distinguished from other pili by their D-mannose-sensitive agglutinatination of erythrocytes. In E. coli, type I pili consist of a short tip fibrillum made up of the adhesin protein (FimH) and two minor subunits (FimG and FimF) that is joined to the pilus rod, a homopolymer of ~1000 FimA subunits.	got7fsn_ti	type I fimbriae|type I pili|type 1 pilus	https://github.com/geneontology/go-ontology/issues/14470					pg	2021-03-10T10:24:04Z						cellular_component											owl:Class	
GO:0022407	biolink:NamedThing	regulation of cell-cell adhesion	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.	got7fsn_ti														biological_process											owl:Class	
GO:0010343	biolink:NamedThing	singlet oxygen-mediated programmed cell death	Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.	got7fsn_ti	programmed cell death in response to singlet oxygen|light-dependent programmed cell death													biological_process											owl:Class	
GO:0006771	biolink:NamedThing	riboflavin metabolic process	The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).	got7fsn_ti	vitamin G metabolism|vitamin B2 metabolism|riboflavin metabolism|vitamin G metabolic process|vitamin B2 metabolic process											Wikipedia:Riboflavin		biological_process											owl:Class	
GO:0021967	biolink:NamedThing	corticospinal neuron axon guidance through the cerebral cortex	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues.	got7fsn_ti	corticospinal neuron axon pathfinding through the cerebral cortex													biological_process											owl:Class	
GO:0140650	biolink:NamedThing	radial glia-guided pyramidal neuron migration	The radial migration of a pyramidal neuron along radial glial cells.	got7fsn_ti	radial glia-dependent neuronal migration	https://github.com/geneontology/go-ontology/issues/21476					pg	2021-05-25T12:48:12Z						biological_process											owl:Class	
GO:0015304	biolink:NamedThing	glucose uniporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in).	got7fsn_ti	galactose, glucose uniporter activity													molecular_function											owl:Class	
GO:1990580	biolink:NamedThing	regulation of cytoplasmic translational termination	Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.	got7fsn_ti							vw	2014-12-10T15:48:55Z						biological_process											owl:Class	
GO:0003954	biolink:NamedThing	NADH dehydrogenase activity	Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.	got7fsn_ti	NADH diaphorase activity|NADH:(acceptor) oxidoreductase activity|NADH hydrogenase activity|NADH oxidoreductase activity|dihydrocodehydrogenase I dehydrogenase activity|diphosphopyrinase activity|type 1 dehydrogenase activity|NADH-menadione oxidoreductase activity|dihydronicotinamide adenine dinucleotide dehydrogenase activity|NADH:cytochrome c oxidoreductase activity|diphosphopyridine diaphorase activity|beta-NADH dehydrogenase dinucleotide activity|reduced diphosphopyridine nucleotide diaphorase activity|NADH2 dehydrogenase activity|diaphorase activity|type I dehydrogenase activity|cytochrome c reductase activity|DPNH diaphorase activity|NADH:acceptor oxidoreductase activity											MetaCyc:NADH-DEHYDROGENASE-RXN|RHEA:11356		molecular_function											owl:Class	
GO:0052907	biolink:NamedThing	23S rRNA (adenine(1618)-N(6))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.	got7fsn_ti	rRNA large subunit methyltransferase F activity|M(6)A(1618) activity											EC:2.1.1.181|KEGG_REACTION:R07232|MetaCyc:RXN-11596|RHEA:16497		molecular_function											owl:Class	
GO:0043842	biolink:NamedThing	Kdo transferase activity	Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP.	got7fsn_ti	3-deoxy-D-manno-octulosonic-acid transferase activity|WaaA|kdtA											EC:2.4.99.13|MetaCyc:KDOTRANS-RXN|EC:2.4.99.15|EC:2.4.99.12|EC:2.4.99.14|MetaCyc:KDOTRANS2-RXN		molecular_function											owl:Class	
GO:0050050	biolink:NamedThing	leucine N-acetyltransferase activity	Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+).	got7fsn_ti	acetyl-CoA:L-leucine N-acetyltransferase activity|leucine acetyltransferase activity											RHEA:20089|EC:2.3.1.66|KEGG_REACTION:R01089|MetaCyc:LEUCINE-N-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0140634	biolink:NamedThing	CARD8 inflammasome complex	An inflammasome complex that consists of CARD8 and CASP1.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21092					pg	2021-04-09T11:24:48Z						cellular_component											owl:Class	
GO:0052086	biolink:NamedThing	suppression by symbiont of host B-cell mediated immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	down-regulation by symbiont of host B-cell mediated immune response|inhibition by symbiont of host B-cell mediated immune response|downregulation by symbiont of host B-cell mediated immune response|down regulation by symbiont of host B-cell mediated immune response|negative regulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction										GO:0052281			biological_process											owl:Class	
GO:0019628	biolink:NamedThing	urate catabolic process	The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine.	got7fsn_ti	urate catabolism|uric acid catabolic process|urate breakdown|urate degradation											MetaCyc:P165-PWY		biological_process											owl:Class	
GO:0034966	biolink:NamedThing	intronic box H/ACA snoRNA processing	Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0002133	biolink:NamedThing	polycystin complex	A stable heterodimeric complex composed of polycystin-1 and polycystin-2.	got7fsn_ti					Different forms of the complex differing in type of N-glycosylation of polycystin-1 can exist (endoglycosidase sensitive and endoglycosidase resistant).									cellular_component											owl:Class	
GO:0033211	biolink:NamedThing	adiponectin-activated signaling pathway	A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	adiponectin-mediated signaling pathway|adipocytokine signaling pathway|adiponectin-mediated signalling pathway													biological_process											owl:Class	
GO:0097616	biolink:NamedThing	positive regulation by host of symbiont type IV pilus-dependent motility	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by host of bacterial type IV pilus-dependent motility						pr	2014-06-10T13:19:51Z						biological_process											owl:Class	
GO:0097615	biolink:NamedThing	modulation by host of symbiont type IV pilus-dependent motility	The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by host of bacterial type IV pilus-dependent motility						pr	2014-06-10T13:17:13Z						biological_process											owl:Class	
GO:2001156	biolink:NamedThing	regulation of proline catabolic process to glutamate	Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate.	got7fsn_ti	regulation of proline degradation to glutamate|regulation of proline breakdown to glutamate|regulation of proline oxidation						mcc	2011-10-25T08:54:37Z						biological_process											owl:Class	
GO:0009970	biolink:NamedThing	cellular response to sulfate starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.	got7fsn_ti	cellular response to sulphate starvation													biological_process											owl:Class	
GO:0050284	biolink:NamedThing	sinapate 1-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.	got7fsn_ti	uridine diphosphoglucose-sinapate glucosyltransferase activity|UDPglucose:sinapate D-glucosyltransferase activity|uridine 5'-diphosphoglucose-hydroxycinnamic acid acylglucosyltransferase activity|UDPglucose:sinapic acid glucosyltransferase activity|UDP-glucose:sinapate D-glucosyltransferase activity											EC:2.4.1.120|RHEA:13305|MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0060328	biolink:NamedThing	cytoplasmic actin-based contraction involved in forward cell motility	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell.	got7fsn_ti	cytoplasmic actin-based contraction involved in forward cell locomotion													biological_process											owl:Class	
GO:0061017	biolink:NamedThing	hepatoblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.	got7fsn_ti							dph	2010-02-02T09:08:03Z						biological_process											owl:Class	
GO:0010117	biolink:NamedThing	photoprotection	Protection mechanism used by plants under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0050377	biolink:NamedThing	UDP-glucose 4,6-dehydratase activity	Catalysis of the reaction: UDP-D-glucose = H(2)O + UDP-4-dehydro-6-deoxy-D-glucose.	got7fsn_ti	UDPglucose 4,6-hydro-lyase activity|UDP-D-glucose oxidoreductase activity|UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)|UDP-D-glucose-4,6-hydrolyase activity|UDPglucose 4,6-dehydratase activity|UDP-glucose 4,6-hydro-lyase activity											RHEA:21500|EC:4.2.1.76|MetaCyc:UDP-GLUCOSE-46-DEHYDRATASE-RXN|KEGG_REACTION:R00293		molecular_function											owl:Class	
GO:0050366	biolink:NamedThing	tyramine N-feruloyltransferase activity	Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.	got7fsn_ti	feruloyltyramine synthase activity|feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase activity|tyramine feruloyltransferase activity|tyramine N-feruloyl-CoA transferase activity|feruloyl-CoA tyramine N-feruloyl-CoA transferase activity											EC:2.3.1.110|MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN|RHEA:19685		molecular_function											owl:Class	
GO:0019835	biolink:NamedThing	cytolysis	The rupture of cell membranes and the loss of cytoplasm.	got7fsn_ti	holin|bacteriocin activity|lysin activity|lysis|necrosis|autolysin activity|bacteriolytic toxin activity											Wikipedia:Cytolysis		biological_process											owl:Class	
GO:0080042	biolink:NamedThing	ADP-glucose pyrophosphohydrolase activity	Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:1903303	biolink:NamedThing	negative regulation of pyruvate kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.	got7fsn_ti	negative regulation of phosphoenolpyruvate kinase activity|negative regulation of phosphoenol transphosphorylase activity|down regulation of phosphoenol transphosphorylase activity|downregulation of phosphoenolpyruvate kinase activity|inhibition of pyruvate kinase activity|downregulation of pyruvate kinase activity|inhibition of phosphoenol transphosphorylase activity|down regulation of phosphoenolpyruvate kinase activity|down-regulation of phosphoenolpyruvate kinase activity|inhibition of phosphoenolpyruvate kinase activity|down-regulation of pyruvate kinase activity|downregulation of phosphoenol transphosphorylase activity|negative regulation of ATP:pyruvate 2-O-phosphotransferase activity|downregulation of ATP:pyruvate 2-O-phosphotransferase activity|down-regulation of ATP:pyruvate 2-O-phosphotransferase activity|down regulation of pyruvate kinase activity|down-regulation of phosphoenol transphosphorylase activity|inhibition of ATP:pyruvate 2-O-phosphotransferase activity|down regulation of ATP:pyruvate 2-O-phosphotransferase activity						mr	2014-08-15T23:25:58Z						biological_process											owl:Class	
GO:0051348	biolink:NamedThing	negative regulation of transferase activity	Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.	got7fsn_ti	down-regulation of transferase activity|transferase inhibitor|downregulation of transferase activity|inhibition of transferase activity|down regulation of transferase activity				This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.									biological_process											owl:Class	
GO:0042496	biolink:NamedThing	detection of diacyl bacterial lipopeptide	The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups.	got7fsn_ti	detection of diacylated bacterial lipoprotein|perception of diacylated bacterial lipopeptide|perception of diacylated bacterial lipoprotein				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.									biological_process											owl:Class	
GO:0102600	biolink:NamedThing	cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity	Catalysis of the reaction: 12,13beta-epoxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P).	got7fsn_ti												MetaCyc:RXN-15384		molecular_function											owl:Class	
GO:0072528	biolink:NamedThing	pyrimidine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.	got7fsn_ti	pyrimidine-containing compound formation|pyrimidine-containing compound synthesis|pyrimidine and derivative biosynthetic process|pyrimidine-containing compound biosynthesis|pyrimidine-containing compound anabolism						mah	2011-01-04T03:27:36Z						biological_process											owl:Class	
GO:0018715	biolink:NamedThing	9-phenanthrol UDP-glucuronosyltransferase activity	Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP.	got7fsn_ti												UM-BBD_reactionID:r0567		molecular_function											owl:Class	
GO:0035632	biolink:NamedThing	mitochondrial prohibitin complex	A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.	got7fsn_ti	mitochondrial inner membrane prohibitin complex						bf	2010-12-21T10:38:59Z						cellular_component											owl:Class	
GO:0044508	biolink:NamedThing	glucagon-like peptide 1 receptor activity	Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein.	got7fsn_ti							jl	2012-02-23T04:50:25Z						molecular_function											owl:Class	
GO:0048533	biolink:NamedThing	sporocyte differentiation	The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.	got7fsn_ti	sporocyte development|sporocyte morphogenesis													biological_process											owl:Class	
GO:0036187	biolink:NamedThing	cell growth mode switching, budding to filamentous	The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans.	got7fsn_ti	yeast to hyphal transition						bf	2012-04-18T11:32:57Z						biological_process											owl:Class	
GO:0055131	biolink:NamedThing	C3HC4-type RING finger domain binding	Binding to a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.	got7fsn_ti							jid	2009-10-22T02:20:33Z						molecular_function											owl:Class	
GO:0010068	biolink:NamedThing	protoderm histogenesis	The formation of the primary meristem or meristematic tissue that gives rise to the epidermis.	got7fsn_ti														biological_process											owl:Class	
GO:0086053	biolink:NamedThing	AV node cell to bundle of His cell communication by electrical coupling	The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti	atrioventricular node cell to bundle of His cell communication by electrical coupling						dph	2011-11-16T12:31:08Z						biological_process											owl:Class	
GO:0032040	biolink:NamedThing	small-subunit processome	A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.	got7fsn_ti	SSU processome|small subunit processome													cellular_component											owl:Class	
GO:0022876	biolink:NamedThing	protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	galactosamine PTS transporter activity													molecular_function											owl:Class	
GO:0019196	biolink:NamedThing	galactosamine transmembrane transporter activity	Enables the transfer of galactosamine from one side of a membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative.	got7fsn_ti	galactosamine porter activity										GO:0019195			molecular_function											owl:Class	
GO:0004071	biolink:NamedThing	aspartate-ammonia ligase activity	Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine.	got7fsn_ti	L-asparagine synthetase activity|asparagine synthetase activity|L-aspartate:ammonia ligase (AMP-forming)											MetaCyc:ASNSYNA-RXN|RHEA:11372|EC:6.3.1.1		molecular_function											owl:Class	
GO:0044676	biolink:NamedThing	formyl-methanofuran dehydrogenase (molybdenum enzyme) complex	A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.	got7fsn_ti							jl	2012-08-09T10:56:51Z						cellular_component											owl:Class	
GO:0006578	biolink:NamedThing	amino-acid betaine biosynthetic process	The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid.	got7fsn_ti	betaine formation|betaine synthesis|betaine anabolism|betaine biosynthesis|betaine biosynthetic process													biological_process											owl:Class	
GO:0097148	biolink:NamedThing	BCL-2 complex	A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:51:16Z						cellular_component											owl:Class	
GO:0045574	biolink:NamedThing	sterigmatocystin catabolic process	The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	got7fsn_ti	sterigmatocystin breakdown|sterigmatocystin catabolism|sterigmatocystin degradation													biological_process											owl:Class	
GO:0050873	biolink:NamedThing	brown fat cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.	got7fsn_ti	brown adipocyte differentiation|brown adipocyte cell differentiation													biological_process											owl:Class	
GO:0044321	biolink:NamedThing	response to leptin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism].	got7fsn_ti	response to leptin stimulus						jl	2010-07-14T02:31:20Z						biological_process											owl:Class	
GO:0071249	biolink:NamedThing	cellular response to nitrate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.	got7fsn_ti							mah	2009-12-03T03:02:06Z						biological_process											owl:Class	
GO:0050045	biolink:NamedThing	laminaribiose phosphorylase activity	Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate.	got7fsn_ti	3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase activity											RHEA:16617|EC:2.4.1.31|MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN		molecular_function											owl:Class	
GO:0102505	biolink:NamedThing	apigeninidin 5-O-glucosyltransferase activity	Catalysis of the reaction: apigeninidin + UDP-alpha-D-glucose <=> apigeninidin 5-O-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-14427		molecular_function											owl:Class	
GO:0005588	biolink:NamedThing	collagen type V trimer	A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils.	got7fsn_ti														cellular_component											owl:Class	
GO:0098851	biolink:NamedThing	double-stranded miRNA binding	Binding to double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures.	got7fsn_ti	miRNA duplex binding													molecular_function											owl:Class	
GO:0003725	biolink:NamedThing	double-stranded RNA binding	Binding to double-stranded RNA.	got7fsn_ti	dsRNA binding													molecular_function											owl:Class	
GO:0036170	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to starvation	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.	got7fsn_ti							bf	2012-03-27T03:53:28Z						biological_process											owl:Class	
GO:0003999	biolink:NamedThing	adenine phosphoribosyltransferase activity	Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.	got7fsn_ti	adenylic pyrophosphorylase activity|transphosphoribosidase activity|AMP:diphosphate phospho-D-ribosyltransferase activity|AMP pyrophosphorylase activity|adenylate pyrophosphorylase activity|adenosine phosphoribosyltransferase activity|adenine phosphoribosylpyrophosphate transferase activity|AMP-pyrophosphate phosphoribosyltransferase activity|APRT activity|AMP diphosphorylase activity											EC:2.4.2.7|Reactome:R-HSA-74213|MetaCyc:ADENPRIBOSYLTRAN-RXN|RHEA:16609		molecular_function											owl:Class	
GO:0003261	biolink:NamedThing	cardiac muscle progenitor cell migration to the midline involved in heart field formation	The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart.	got7fsn_ti	myocardial progenitor cell midline convergence						dph	2009-10-15T01:57:55Z						biological_process											owl:Class	
GO:1990585	biolink:NamedThing	hydroxyproline O-arabinosyltransferase activity	Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline <=> a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline + UDP + H+.	got7fsn_ti	HPAT						tb	2014-12-12T18:22:20Z						molecular_function											owl:Class	
GO:0018451	biolink:NamedThing	epoxide dehydrogenase activity	Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0595		molecular_function											owl:Class	
GO:0050417	biolink:NamedThing	glutamin-(asparagin-)ase activity	Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate.	got7fsn_ti	L-ASNase/L-GLNase activity|L-asparagine/L-glutamine amidohydrolase activity|L-glutamine(L-asparagine) amidohydrolase activity|glutaminase-(asparagin-)ase activity|glutaminase-asparaginase activity											MetaCyc:GLUTAMINASE-ASPARAGIN-ASE-RXN|EC:3.5.1.38		molecular_function											owl:Class	
GO:0099006	biolink:NamedThing	viral entry via permeabilization of endosomal membrane	The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid.  In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen.	got7fsn_ti	viral penetration via permeabilization of host membrane											VZ:985		biological_process											owl:Class	
GO:0086039	biolink:NamedThing	P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential	A calcium-transporting P-type ATPase activity involved in regulation of the plasma membrane potential.	got7fsn_ti	calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential						tb	2011-11-11T03:33:44Z						molecular_function											owl:Class	
GO:0005388	biolink:NamedThing	P-type calcium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(in) = ADP + phosphate + Ca2+(out).	got7fsn_ti	Ca2+-transporting ATPase activity|Ca(2+)-transporting ATPase activity|ATPase-coupled calcium transmembrane transporter activity|calcium-translocating P-type ATPase activity|calcium transmembrane transporter activity, phosphorylative mechanism|sarco(endo)plasmic reticulum Ca2+-ATPase|calcium transporting ATPase activity|calcium-transporting ATPase activity|ATP-dependent calcium transmembrane transporter activity|calcium efflux ATPase|calcium pump											EC:7.2.2.10|Reactome:R-HSA-418365|Reactome:R-HSA-427910|RHEA:18105|Reactome:R-HSA-418309|Reactome:R-HSA-936883|MetaCyc:3.6.3.8-RXN		molecular_function											owl:Class	
GO:1900586	biolink:NamedThing	arugosin catabolic process	The chemical reactions and pathways resulting in the breakdown of arugosin.	got7fsn_ti	arugosin degradation|arugosin catabolism|arugosin breakdown						di	2012-05-15T06:48:37Z						biological_process											owl:Class	
GO:0075504	biolink:NamedThing	macropinosomal membrane permeabilization involved in viral entry into host cell	Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm.	got7fsn_ti	viral entry into host cell via macropinocytosis followed by macropinosomal membrane permeabilization						jl	2010-06-02T02:48:36Z						biological_process											owl:Class	
GO:0102611	biolink:NamedThing	(+)-secoisolariciresinol monoglucoside glucosyltransferase activity	Catalysis of the reaction: (+)-secoisolariciresinol monoglucoside + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol diglucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-15443		molecular_function											owl:Class	
GO:0042973	biolink:NamedThing	glucan endo-1,3-beta-D-glucosidase activity	Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.	got7fsn_ti	callase activity|1,3-beta-D-glucan 3-glucanohydrolase activity|kitalase activity|endo-1,3-beta-glucosidase activity|endo-(1->3)-beta-D-glucanase activity|endo-(1,3)-beta-D-glucanase activity|laminaranase activity|(1->3)-beta-glucan 3-glucanohydrolase activity|beta-1,3-glucanase|1,3-beta-D-glucan glucanohydrolase activity|(1->3)-beta-glucan endohydrolase activity|laminarinase activity|endo-1,3-beta-D-glucanase|endo-1,3-beta-glucanase activity|oligo-1,3-glucosidase activity											EC:3.2.1.39|MetaCyc:3.2.1.39-RXN		molecular_function											owl:Class	
GO:0031884	biolink:NamedThing	type 1 member 1 taste receptor binding	Binding to a type 1 member 1 taste receptor.	got7fsn_ti	type 1 member 1 taste receptor ligand													molecular_function											owl:Class	
GO:0033562	biolink:NamedThing	co-transcriptional gene silencing by RNA interference machinery	A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin.	got7fsn_ti	cotranscriptional gene silencing by RNA interference machinery|RNAi-mediated CTGS|small RNA-mediated cotranscriptional gene silencing|cotranscriptional gene silencing by small RNA|co-transcriptional gene silencing by small RNA													biological_process											owl:Class	
GO:0003863	biolink:NamedThing	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.	got7fsn_ti	3-methyl-2-oxobutanoate:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)|branched-chain keto acid dehydrogenase activity|2-oxoisovalerate (lipoate) dehydrogenase activity|alpha-oxoisocaproate dehydrogenase activity|BCOAD activity|alpha-ketoisocaproic dehydrogenase activity|dehydrogenase, branched chain alpha-keto acid activity|alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase activity|alpha-ketoacid dehydrogenase activity|branched-chain ketoacid dehydrogenase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity|alpha-ketoisovalerate dehydrogenase activity|2-oxoisocaproate dehydrogenase activity|branched-chain 2-keto acid dehydrogenase activity|alpha-keto-alpha-methylvalerate dehydrogenase activity|branched-chain alpha-oxo acid dehydrogenase activity|branched chain keto acid dehydrogenase activity|3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating) activity|branched-chain alpha-keto acid dehydrogenase activity|BCKDH activity|branched-chain (-2-oxoacid) dehydrogenase (BCD) activity|branched-chain 2-oxo acid dehydrogenase activity|alpha-ketoisocaproate dehydrogenase activity|dehydrogenase, 2-oxoisovalerate (lipoate) activity	https://github.com/geneontology/go-ontology/issues/21144									GO:0003826	MetaCyc:1.2.4.4-RXN|EC:1.2.4.4|RHEA:13457		molecular_function											owl:Class	
GO:0102962	biolink:NamedThing	4,4'-diapo-zeta-carotene desaturase activity	Catalysis of the reaction: all-trans-4,4'-diapo-zeta-carotene + FAD + H+ = 4,4'-diaponeurosporene + FADH2.	got7fsn_ti												RHEA:31403|MetaCyc:RXN-9305		molecular_function											owl:Class	
GO:0030345	biolink:NamedThing	structural constituent of tooth enamel	The action of a molecule that contributes to the structural integrity of tooth enamel.	got7fsn_ti														molecular_function											owl:Class	
GO:0030021	biolink:NamedThing	extracellular matrix structural constituent conferring compression resistance	A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.	got7fsn_ti	core extracellular matrix|core matrisome				Extracellular matrix proteoglycans may be annotated to this term. PMID:8346704									molecular_function											owl:Class	
GO:0002371	biolink:NamedThing	dendritic cell cytokine production	Any process that contributes to cytokine production by a dendritic cell.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0033771	biolink:NamedThing	licodione synthase activity	Catalysis of the reaction: H(+) + liquiritigenin + NADPH + O(2) = H(2)O + licodione + NADP(+).	got7fsn_ti	(2S)-flavanone 2-hydroxylase activity|liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming) activity											MetaCyc:1.14.13.87-RXN|KEGG_REACTION:R07198|EC:1.14.14.140|RHEA:15697		molecular_function											owl:Class	
GO:0102809	biolink:NamedThing	delphinidin 3-O-glucoside 2''-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-beta-D-glucoside <=> H+ + delphinidin 3-O-sophoroside + UDP.	got7fsn_ti												MetaCyc:RXN-8178		molecular_function											owl:Class	
GO:0043786	biolink:NamedThing	cinnamate reductase activity	Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+.	got7fsn_ti												EC:1.3.1.-		molecular_function											owl:Class	
GO:0046210	biolink:NamedThing	nitric oxide catabolic process	The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	got7fsn_ti	nitric oxide degradation|nitric oxide catabolism|nitric oxide breakdown													biological_process											owl:Class	
GO:0072491	biolink:NamedThing	toluene-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.	got7fsn_ti	toluene-containing compound catabolism|toluene-containing compound degradation|toluene-containing compound breakdown|toluene and derivative catabolic process						mah	2010-12-14T03:51:03Z						biological_process											owl:Class	
GO:0098784	biolink:NamedThing	biofilm matrix organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix.	got7fsn_ti	biofilm matrix organization and biogenesis													biological_process											owl:Class	
GO:0004153	biolink:NamedThing	dihydropterin deaminase activity	Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3.	got7fsn_ti														molecular_function											owl:Class	
GO:0018590	biolink:NamedThing	methylsilanetriol hydroxylase activity	Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol.	got7fsn_ti												UM-BBD_reactionID:r0640		molecular_function											owl:Class	
GO:0043635	biolink:NamedThing	methylnaphthalene catabolic process	The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar.	got7fsn_ti	1-MN catabolism|1-methylnaphthalene catabolic process|2-MN catabolic process|1-methylnaphthalene catabolism|1-MN catabolic process|2-MN catabolism|2-methylnaphthalene catabolic process|2-methylnaphthalene catabolism													biological_process											owl:Class	
GO:0061787	biolink:NamedThing	peptidoglycan cross-bridge peptide endopeptidase activity	A peptidoglycan endopeptidase activity that acts on a peptidoglycan cross-bridge.	got7fsn_ti	lysostaphin activity						dph	2016-09-07T16:54:02Z						molecular_function											owl:Class	
GO:0052582	biolink:NamedThing	(+)-menthofuran synthase activity	Catalysis of the reaction: (R)-pulegone + H(+) + NADPH + O(2) = (R)-menthofuran + 2 H(2)O + NADP(+).	got7fsn_ti	(+)-pulegone 9-hydroxylase activity|(+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating) activity|menthofuran synthase activity|cytochrome P450 menthofuran synthase activity|(+)-MFS activity						ai	2010-08-09T04:47:42Z				KEGG_REACTION:R08923|EC:1.14.14.143|RHEA:25658|MetaCyc:1.14.13.104-RXN		molecular_function											owl:Class	
GO:0061218	biolink:NamedThing	negative regulation of mesonephros development	Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti							dph	2010-08-17T03:43:06Z						biological_process											owl:Class	
GO:0060067	biolink:NamedThing	cervix development	The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.	got7fsn_ti	Mullerian tract development													biological_process											owl:Class	
GO:0046660	biolink:NamedThing	female sex differentiation	The establishment of the sex of a female organism by physical differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0047326	biolink:NamedThing	inositol tetrakisphosphate 5-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.	got7fsn_ti	inositol 1,3,4,6-tetrakisphosphate 5-kinase activity|inositol-tetrakisphosphate 5-kinase activity|1D-myo-inositol-tetrakisphosphate 5-kinase activity|ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase activity											MetaCyc:2.7.1.140-RXN|Reactome:R-HSA-1855228|RHEA:12717|EC:2.7.1.140		molecular_function											owl:Class	
GO:0030936	biolink:NamedThing	transmembrane collagen trimer	Any collagen trimer that passes through a lipid bilayer membrane.	got7fsn_ti	MACIT													cellular_component											owl:Class	
GO:0060069	biolink:NamedThing	Wnt signaling pathway, regulating spindle positioning	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle.	got7fsn_ti	Wnt receptor signaling pathway, regulating spindle positioning|Wnt-activated signaling pathway, regulating spindle positioning|Wnt receptor signalling pathway, regulating spindle positioning|non-canonical Wnt signaling pathway													biological_process											owl:Class	
GO:0072399	biolink:NamedThing	response to cytokinesis checkpoint signaling	A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling.	got7fsn_ti	cytokinesis checkpoint effector process|response to signal involved in cytokinesis checkpoint						mah	2010-12-08T03:23:32Z			GO:0072420			biological_process											owl:Class	
GO:0009044	biolink:NamedThing	xylan 1,4-beta-xylosidase activity	Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini.	got7fsn_ti	exo-1,4-xylosidase activity|beta-D-xylopyranosidase activity|exo-1,4-beta-xylosidase activity|1,4-beta-D-xylan xylohydrolase activity|beta-xylosidase activity|xylobiase activity|exo-1,4-beta-D-xylosidase activity											MetaCyc:3.2.1.37-RXN|EC:3.2.1.37		molecular_function											owl:Class	
GO:0051218	biolink:NamedThing	tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)	The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide).	got7fsn_ti												RESID:AA02376		biological_process											owl:Class	
GO:0005173	biolink:NamedThing	stem cell factor receptor binding	Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.	got7fsn_ti	SCF|stem cell factor receptor ligand|stem cell factor|KIT binding|SCFR binding													molecular_function											owl:Class	
GO:0050782	biolink:NamedThing	galactose uniporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).	got7fsn_ti	galactose, glucose uniporter activity													molecular_function											owl:Class	
GO:0047269	biolink:NamedThing	poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity	Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP.	got7fsn_ti	uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase activity|UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity											EC:2.4.1.70|MetaCyc:2.4.1.70-RXN|RHEA:21012		molecular_function											owl:Class	
GO:0103099	biolink:NamedThing	UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 5-methylthiopentylhydroximate <=> H+ + 4-methylthiobutyldesulfoglucosinolate + UDP.	got7fsn_ti												MetaCyc:RXNQT-4324|EC:2.4.1.195		molecular_function											owl:Class	
GO:0021804	biolink:NamedThing	negative regulation of cell adhesion in ventricular zone	The process that results in the loss of attachments of a cell in the ventricular zone.	got7fsn_ti	downregulation of cell adhesion in ventricular zone|down regulation of cell adhesion in ventricular zone|inhibition of cell adhesion in ventricular zone|down-regulation of cell adhesion in ventricular zone													biological_process											owl:Class	
GO:0071116	biolink:NamedThing	alpha6-beta1 integrin-CYR61 complex	A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.	got7fsn_ti	ITGA6-ITGB1-CYR61 complex						mah	2009-11-13T02:19:23Z						cellular_component											owl:Class	
GO:0098033	biolink:NamedThing	icosahedral viral capsid, neck fiber	A fiber attached to the neck at the base of some icosahedral viral capsids.	got7fsn_ti							bm	2012-07-19T15:07:39Z						cellular_component											owl:Class	
GO:0006541	biolink:NamedThing	glutamine metabolic process	The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.	got7fsn_ti	glutamine metabolism													biological_process											owl:Class	
GO:0071191	biolink:NamedThing	protocadherin-alpha-v7-protocadherin-gamma-b4 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti	Pcdha7-Pcdhgb2 complex						mah	2009-11-23T04:30:51Z						cellular_component											owl:Class	
GO:0045112	biolink:NamedThing	integrin biosynthetic process	The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules.	got7fsn_ti	integrin anabolism|integrin synthesis|integrin biosynthesis|integrin formation													biological_process											owl:Class	
GO:0060265	biolink:NamedThing	positive regulation of respiratory burst involved in inflammatory response	Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	got7fsn_ti	positive regulation of respiratory burst involved in acute inflammatory response													biological_process											owl:Class	
GO:0102836	biolink:NamedThing	1-18:1-2-16:1-monogalactosyldiacylglyceroldesaturase activity	Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8296|EC:1.14.19.23		molecular_function											owl:Class	
GO:0047985	biolink:NamedThing	hydrogen dehydrogenase activity	Catalysis of the reaction: H2 + NAD+ = H+ + NADH.	got7fsn_ti	NAD-linked hydrogenase activity|H(2):NAD(+) oxidoreductase activity|H2:NAD+ oxidoreductase activity|hydrogen:NAD+ oxidoreductase activity|bidirectional hydrogenase activity|hydrogenase activity											RHEA:24636|MetaCyc:HYDROGEN-DEHYDROGENASE-RXN|EC:1.12.1.2		molecular_function											owl:Class	
GO:0003908	biolink:NamedThing	methylated-DNA-[protein]-cysteine S-methyltransferase activity	Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.	got7fsn_ti	methylated-DNA-protein-cysteine S-methyltransferase activity|DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase activity|6-O-methylguanine-DNA methyltransferase activity|MGMT|O-6-methylguanine-DNA-alkyltransferase activity|O6-alkylguanine-DNA alkyltransferase|DNA-6-O-methylguanine:[protein]-L-cysteine S-methyltransferase activity											MetaCyc:2.1.1.63-RXN|RHEA:24000|EC:2.1.1.63|Reactome:R-HSA-73892		molecular_function											owl:Class	
GO:0098842	biolink:NamedThing	postsynaptic early endosome	An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling.	got7fsn_ti					Commonly used markers for postsynaptic early endosomes include RAB5A and EEA1.									cellular_component											owl:Class	
GO:0003308	biolink:NamedThing	negative regulation of Wnt signaling pathway involved in heart development	Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.	got7fsn_ti	negative regulation of Wnt receptor signaling pathway involved in heart development|negative regulation of Wnt receptor signalling pathway involved in heart development|negative regulation of Wnt-activated signaling pathway involved in heart development						dph	2009-10-22T12:36:11Z						biological_process											owl:Class	
GO:0021981	biolink:NamedThing	subpallium radially oriented migration	The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.	got7fsn_ti														biological_process											owl:Class	
GO:0070947	biolink:NamedThing	neutrophil-mediated killing of fungus	The directed killing of a fungal cell by a neutrophil.	got7fsn_ti	neutrophil mediated killing of fungus						mah	2009-10-01T02:07:44Z						biological_process											owl:Class	
GO:0097470	biolink:NamedThing	ribbon synapse	Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.	got7fsn_ti	synapsis fasciolaris						pr	2013-02-21T07:40:01Z				NIF_Subcellular:sao1884931180		cellular_component											owl:Class	
GO:0042820	biolink:NamedThing	vitamin B6 catabolic process	The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	got7fsn_ti	vitamin B6 degradation|vitamin B6 breakdown|vitamin B6 catabolism													biological_process											owl:Class	
GO:0017060	biolink:NamedThing	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.	got7fsn_ti	guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity|Lewis blood group alpha-(1,3/4)-fucosyltransferase activity|Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity|Lewis blood group alpha-(1->3/4)-fucosyltransferase activity|Lewis FT activity|guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity|alpha-(1->4)-L-fucosyltransferase activity|guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity|Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity|blood group Lewis alpha-4-fucosyltransferase activity|alpha(1,4)-L-fucosyltransferase activity|GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity|beta-acetylglucosaminylsaccharide fucosyltransferase activity|(Lea)-dependent (alpha-3/4)-fucosyltransferase activity|Lewis alpha-(1->3/4)-fucosyltransferase activity|alpha-(1,4)-L-fucosyltransferase activity|blood-group substance Le(a)-dependent fucosyltransferase activity|Lewis alpha-(1,3/4)-fucosyltransferase activity|FucT-II activity|GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity|galactoside 3(4)-L-fucosyltransferase activity|alpha-4-L-fucosyltransferase activity|3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity|alpha-(1,3/1,4) fucosyltransferase III activity|blood-group substance Lea-dependent fucosyltransferase|(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity											Reactome:R-HSA-9603986|MetaCyc:2.4.1.65-RXN|RHEA:23628|Reactome:R-HSA-5693925|EC:2.4.1.65		molecular_function											owl:Class	
GO:0033792	biolink:NamedThing	bile-acid 7alpha-dehydroxylase activity	Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2, and lithocholate + FAD + H2O = chenodeoxycholate + FADH2.	got7fsn_ti	bile acid 7-dehydroxylase activity|cholate 7alpha-dehydroxylase activity|deoxycholate:FAD oxidoreductase (7alpha-dehydroxylating) activity|deoxycholate:NAD+ oxidoreductase activity|7alpha-dehydroxylase activity											MetaCyc:RXN-8658|MetaCyc:RXN-8659|EC:1.17.99.5		molecular_function											owl:Class	
GO:0102995	biolink:NamedThing	angelicin synthase activity	Catalysis of the reaction: columbianetin + NADPH + O2 + H+ <=> angelicin + acetone + NADP + 2 H2O.	got7fsn_ti												MetaCyc:RXN-9689|EC:1.14.14.148|RHEA:27481		molecular_function											owl:Class	
GO:0047587	biolink:NamedThing	5-alpha-hydroxysteroid dehydratase activity	Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H(2)O.	got7fsn_ti	5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase (ergosterol-forming)|5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase activity|5alpha-hydroxysteroid dehydratase activity											RHEA:22064|EC:4.2.1.62|KEGG_REACTION:R03675|MetaCyc:5-ALPHA-HYDROXYSTEROID-DEHYDRATASE-RXN		molecular_function											owl:Class	
GO:0018241	biolink:NamedThing	protein O-linked glycosylation via hydroxylysine	The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.	got7fsn_ti	protein amino acid O-linked glycosylation via hydroxylysine											RESID:AA0153		biological_process											owl:Class	
GO:0071758	biolink:NamedThing	IgW immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti					Note that an IgW immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgW is found in fish.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0071978	biolink:NamedThing	bacterial-type flagellum-dependent swarming motility	Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.	got7fsn_ti	bacterial-type flagellar swarming motility|bacterial-type flagellum-mediated cell swarming						mah	2010-10-21T03:00:14Z						biological_process											owl:Class	
GO:0050731	biolink:NamedThing	positive regulation of peptidyl-tyrosine phosphorylation	Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.	got7fsn_ti	activation of peptidyl-tyrosine phosphorylation|upregulation of peptidyl-tyrosine phosphorylation|up regulation of peptidyl-tyrosine phosphorylation|stimulation of peptidyl-tyrosine phosphorylation|up-regulation of peptidyl-tyrosine phosphorylation													biological_process											owl:Class	
GO:0090570	biolink:NamedThing	RNA polymerase I transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter.	got7fsn_ti							tb	2014-05-09T13:26:16Z						cellular_component											owl:Class	
GO:0018341	biolink:NamedThing	peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine	The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine.	got7fsn_ti	peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthetic process|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthesis|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine formation|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine anabolism|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine synthesis													biological_process											owl:Class	
GO:0052737	biolink:NamedThing	pyruvate dehydrogenase (quinone) activity	Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2.	got7fsn_ti	pyruvate:ubiquinone-8-oxidoreductase activity|pyruvic dehydrogenase activity|pyruvate:ubiquinone oxidoreductase activity|pyruvate dehydrogenase activity											EC:1.2.5.1|MetaCyc:RXN-11496|RHEA:27405|KEGG_REACTION:R03145		molecular_function											owl:Class	
GO:0033427	biolink:NamedThing	CAA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CAA codon.	got7fsn_ti	glutamine tRNA				Note that in the standard genetic code, CAA codes for glutamine.									molecular_function											owl:Class	
GO:0002471	biolink:NamedThing	monocyte antigen processing and presentation	The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0010909	biolink:NamedThing	positive regulation of heparan sulfate proteoglycan biosynthetic process	Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.	got7fsn_ti														biological_process											owl:Class	
GO:0014045	biolink:NamedThing	establishment of endothelial blood-brain barrier	Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.	got7fsn_ti	establishment of endothelial blood/brain barrier|establishment of endothelial BBB													biological_process											owl:Class	
GO:0006507	biolink:NamedThing	GPI anchor release	The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0006505	biolink:NamedThing	GPI anchor metabolic process	The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.	got7fsn_ti	glycosylphosphatidylinositol metabolic process|glycosylphosphatidylinositol metabolism|GPI/GSI anchor metabolic process|GPI anchor metabolism|GPI/GSI anchor metabolism										GO:0046472			biological_process											owl:Class	
GO:0016699	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein.	got7fsn_ti	oxidoreductase activity, acting on hydrogen as donor, iron-sulphur protein as acceptor										GO:0016736|GO:0019110	EC:1.12.7.-		molecular_function											owl:Class	
GO:0016138	biolink:NamedThing	glycoside biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.	got7fsn_ti	O-glycoside formation|glycoside anabolism|O-glycoside biosynthesis|glycoside biosynthesis|glycoside formation|O-glycoside biosynthetic process|glycoside synthesis|O-glycoside synthesis|O-glycoside anabolism										GO:0016141			biological_process											owl:Class	
GO:0045242	biolink:NamedThing	isocitrate dehydrogenase complex (NAD+)	Complex that possesses isocitrate dehydrogenase (NAD+) activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0008154	biolink:NamedThing	actin polymerization or depolymerization	Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.	got7fsn_ti														biological_process											owl:Class	
GO:0140327	biolink:NamedThing	flippase activity	Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	flippase activity (exoplasmic to cytosolic leaftlet)				Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the exoplasmic to the cytosolic leaftlet of a membrane).		pg	2019-04-29T12:51:21Z						molecular_function											owl:Class	
GO:0140575	biolink:NamedThing	transmembrane monodehydroascorbate reductase activity	Oxidation of monodehydroascorbate outside of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20602					pg	2021-01-07T16:20:04Z				RHEA:66524		molecular_function											owl:Class	
GO:0002162	biolink:NamedThing	dystroglycan binding	Binding to dystroglycan, a glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).	got7fsn_ti	alpha-dystroglycan binding|beta-dystroglycan binding						hjd	2010-02-22T02:17:58Z			GO:0002163|GO:0002166			molecular_function											owl:Class	
GO:0009962	biolink:NamedThing	regulation of flavonoid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.	got7fsn_ti	regulation of flavonoid anabolism|regulation of flavonoid biosynthesis|regulation of flavonoid synthesis|regulation of flavonoid formation													biological_process											owl:Class	
GO:0035782	biolink:NamedThing	mature natural killer cell chemotaxis	The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.	got7fsn_ti	activated natural killer cell chemotaxis						bf	2011-04-04T11:23:13Z						biological_process											owl:Class	
GO:0102888	biolink:NamedThing	delta-cuprenene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> delta-cuprenene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8431		molecular_function											owl:Class	
GO:1905862	biolink:NamedThing	ferroxidase complex	A protein complex which is capable of ferroxidase activity.	got7fsn_ti					An example of this is FET3 in Saccharomyces cerevisiae (P38993) in PMID:16522632 (inferred from direct assay).		bhm	2017-01-25T10:01:39Z						cellular_component											owl:Class	
GO:0017054	biolink:NamedThing	negative cofactor 2 complex	A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.	got7fsn_ti														cellular_component											owl:Class	
GO:0004650	biolink:NamedThing	polygalacturonase activity	Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.	got7fsn_ti	endo-D-galacturonase activity|endo-polygalacturonase activity|endogalacturonase activity|pectinase activity|pectin polygalacturonase activity|pectolase activity|pectin hydrolase activity|pectin depolymerase activity|poly(1,4-alpha-D-galacturonide) glycanohydrolase activity|poly-alpha-1,4-galacturonide glycanohydrolase activity|endopolygalacturonase activity											EC:3.2.1.15|MetaCyc:RXN-2103		molecular_function											owl:Class	
GO:0043179	biolink:NamedThing	rhythmic excitation	Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit.	got7fsn_ti														biological_process											owl:Class	
GO:0002053	biolink:NamedThing	positive regulation of mesenchymal cell proliferation	The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.	got7fsn_ti	activation of mesenchymal cell proliferation|up-regulation of mesenchymal cell proliferation|stimulation of mesenchymal cell proliferation|up regulation of mesenchymal cell proliferation|upregulation of mesenchymal cell proliferation													biological_process											owl:Class	
GO:0034680	biolink:NamedThing	integrin alpha10-beta1 complex	An integrin complex that comprises one alpha10 subunit and one beta1 subunit.	got7fsn_ti	ITGA10-ITGB1 complex|alpha10-beta1 integrin complex													cellular_component											owl:Class	
GO:0022848	biolink:NamedThing	acetylcholine-gated cation-selective channel activity	Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.	got7fsn_ti	nAChR|acetylcholine-gated cation channel activity|nicotinic acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ionotropic acetylcholine receptor activity|nicotinergic acetylcholine receptor activity										GO:0016904|GO:0004889			molecular_function											owl:Class	
GO:0030942	biolink:NamedThing	endoplasmic reticulum signal peptide binding	Binding to an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum.	got7fsn_ti	ER signal peptide binding													molecular_function											owl:Class	
GO:0005159	biolink:NamedThing	insulin-like growth factor receptor binding	Binding to an insulin-like growth factor receptor.	got7fsn_ti	IGF receptor binding|insulin-like growth factor receptor ligand|insulin-like growth factor										GO:0005067			molecular_function											owl:Class	
GO:0002174	biolink:NamedThing	mammary stem cell proliferation	The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ.	got7fsn_ti							hjd	2010-09-14T01:19:45Z						biological_process											owl:Class	
GO:0044024	biolink:NamedThing	histone kinase activity (H2A-S1 specific)	Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H2A.	got7fsn_ti	histone serine kinase activity (H2A-S1 specific)|histone-serine kinase activity (H2A-S1 specific)													molecular_function											owl:Class	
GO:0046225	biolink:NamedThing	bacteriocin catabolic process	The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.	got7fsn_ti	bacteriocin catabolism|bacteriocin degradation|bacteriocin breakdown													biological_process											owl:Class	
GO:0140068	biolink:NamedThing	histone crotonyltransferase activity	Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.	got7fsn_ti							pg	2017-07-20T16:55:16Z						molecular_function											owl:Class	
GO:0102290	biolink:NamedThing	beta-amyrin monooxygenase activity	Catalysis of the reaction: beta-amyrin + O2 + NADPH + H+ <=> 11alpha-hydroxy-beta-amyrin + H2O + NADP.	got7fsn_ti												EC:1.14.14.152|MetaCyc:RXN-12681|RHEA:31715		molecular_function											owl:Class	
GO:0004531	biolink:NamedThing	deoxyribonuclease II activity	Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products.	got7fsn_ti	acid deoxyribonuclease activity|acid DNase activity|DNase II activity|pancreatic DNase II|deoxyribonucleate 3'-nucleotidohydrolase activity|lysosomal DNase II activity											MetaCyc:3.1.22.1-RXN|EC:3.1.22.1		molecular_function											owl:Class	
GO:0016889	biolink:NamedThing	endodeoxyribonuclease activity, producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.	got7fsn_ti	endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters											EC:3.1.22.-		molecular_function											owl:Class	
GO:0060295	biolink:NamedThing	regulation of cilium movement involved in cell motility	Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.	got7fsn_ti														biological_process											owl:Class	
GO:0051521	biolink:NamedThing	termination of monopolar cell growth	Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0051514	biolink:NamedThing	negative regulation of monopolar cell growth	Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.	got7fsn_ti	inhibition of monopolar cell growth|down regulation of monopolar cell growth|down-regulation of monopolar cell growth|downregulation of monopolar cell growth													biological_process											owl:Class	
GO:0075032	biolink:NamedThing	negative regulation of formation of symbiont germ tube hook structure for appressorium development	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation.	got7fsn_ti	negative regulation of germ tube tip of symbiont on or near the exterior of host|negative regulation of formation of symbiont germ tube hook structure on or near host|negative regulation of symbiont germ tube hook structure formation on or near host													biological_process											owl:Class	
GO:0004731	biolink:NamedThing	purine-nucleoside phosphorylase activity	Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.	got7fsn_ti	PNPase activity|purine deoxyribonucleoside phosphorylase activity|purine ribonucleoside phosphorylase activity|purine deoxynucleoside phosphorylase activity|PUNPI|PUNPII|purine-nucleoside:phosphate ribosyltransferase activity|inosine-guanosine phosphorylase activity|inosine phosphorylase activity|purine nucleoside phosphorylase activity											Reactome:R-HSA-74249|RHEA:19805|EC:2.4.2.1|Reactome:R-HSA-112034|MetaCyc:PNP-RXN|Reactome:R-HSA-74242|Reactome:R-HSA-112033		molecular_function											owl:Class	
GO:0102951	biolink:NamedThing	indole-3-acetyl-phenylalanine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-phenylalanine  + ATP = H+ + indole-3-acetyl-phenylalanine + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-9084		molecular_function											owl:Class	
GO:0032094	biolink:NamedThing	response to food	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.	got7fsn_ti														biological_process											owl:Class	
GO:0071762	biolink:NamedThing	heavy chain immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains.	got7fsn_ti	HCab|IgNAR immunoglobulin complex|IgNAR antibody|Ig NAR immunoglobulin complex				Note that a heavy chain immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgNAR is found in serum of cartilaginous fish as a heavy chain dimer without immunoglobulin light chains. Note that HCab is found in camels as a heavy chain dimer without immunoglobulin light chains.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0021726	biolink:NamedThing	lateral reticular nucleus development	The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0032001	biolink:NamedThing	1,4-alpha-glucan 6-alpha-glucosyltransferase activity	Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.	got7fsn_ti	D-glucosyltransferase|T-enzyme|1,4-alpha-D-glucan:1,4-alpha-D-glucan(D-glucose) 6-alpha-D-glucosyltransferase activity|1,4-alpha-D-glucan 6-alpha-D-glucosyltransferase activity|oligoglucan-branching glycosyltransferase activity											EC:2.4.1.24|MetaCyc:2.4.1.24-RXN		molecular_function											owl:Class	
GO:0018588	biolink:NamedThing	tri-n-butyltin dioxygenase activity	Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin.	got7fsn_ti	TBT dioxygenase activity											UM-BBD_reactionID:r0643		molecular_function											owl:Class	
GO:0031486	biolink:NamedThing	myosin XVI complex	A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.	got7fsn_ti														cellular_component											owl:Class	
GO:0052665	biolink:NamedThing	tRNA (uracil-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil.	got7fsn_ti	tRNA uracil-2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (uracil 2')-methyltransferase activity|S-adenosyl-L-methionine:tRNA uracil-2'-O-methyltransferase activity|transfer ribonucleate uracil 2'-methyltransferase activity|tRNA uracil 2'-methyltransferase activity						ai	2010-10-11T01:05:35Z				RHEA:43100|Reactome:R-HSA-6788707|MetaCyc:RXN0-5143|EC:2.1.1.34		molecular_function											owl:Class	
GO:0031531	biolink:NamedThing	thyrotropin-releasing hormone receptor binding	Binding to a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary.	got7fsn_ti	thyrotropin releasing hormone receptor binding|thyrotropin-releasing hormone receptor ligand										GO:0031888			molecular_function											owl:Class	
GO:0052760	biolink:NamedThing	coenzyme F420-dependent 2,4-dinitrophenol reductase activity	Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.	got7fsn_ti	coenzyme F420-dependent 2,4-dinitrophenol hydride transferase activity|DNP reductase activity						ai	2011-09-28T02:47:31Z				EC:1.3.99.-|UM-BBD_reactionID:r1071		molecular_function											owl:Class	
GO:0047854	biolink:NamedThing	diguanidinobutanase activity	Catalysis of the reaction: 1,4-diguanidinobutane + H(2)O = agmatine + urea.	got7fsn_ti	1,4-diguanidinobutane amidinohydrolase activity											RHEA:13597|MetaCyc:DIGUANIDINOBUTANASE-RXN|EC:3.5.3.20|KEGG_REACTION:R01418		molecular_function											owl:Class	
GO:0106333	biolink:NamedThing	subcortical maternal complex	Comprised of at least NLRP5, OOEP, TLE6, and KHDC3/KHDC3L with evidence of additional SCMC-associated proteins that interact with one or multiple members of the core complex.	got7fsn_ti	SCMC						hjd	2020-10-14T13:49:57Z						cellular_component											owl:Class	
GO:0010168	biolink:NamedThing	ER body	A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.	got7fsn_ti	endoplasmic reticulum body													cellular_component											owl:Class	
GO:0032032	biolink:NamedThing	myosin I tail binding	Binding to the tail region of a myosin I heavy chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0061364	biolink:NamedThing	apoptotic process involved in luteolysis	The apoptotic process that contributes to luteolysis.	got7fsn_ti	apoptosis involved in luteolysis|structural luteolysis						dph	2010-10-14T03:18:49Z						biological_process											owl:Class	
GO:1902742	biolink:NamedThing	apoptotic process involved in development	Any apoptotic process that is involved in anatomical structure development.	got7fsn_ti	apoptotic process involved in anatomical structure development|apoptosis involved in anatomical structure development|activation of apoptosis involved in development of an anatomical structure|apoptotic program involved in development of an anatomical structure|type I programmed cell death involved in development of an anatomical structure|activation of apoptosis involved in anatomical structure development|commitment to apoptosis involved in development of an anatomical structure|apoptotic cell death involved in development of an anatomical structure|apoptotic cell death involved in anatomical structure development|programmed cell death by apoptosis involved in anatomical structure development|programmed cell death by apoptosis involved in development of an anatomical structure|type I programmed cell death involved in anatomical structure development|signaling (initiator) caspase activity involved in development of an anatomical structure|apoptotic program involved in anatomical structure development|induction of apoptosis involved in development of an anatomical structure|apoptotic programmed cell death involved in development of an anatomical structure|apoptosis signaling involved in development of an anatomical structure|apoptosis activator activity involved in anatomical structure development|apoptosis activator activity involved in development of an anatomical structure|commitment to apoptosis involved in anatomical structure development|induction of apoptosis by p53 involved in development of an anatomical structure|induction of apoptosis by p53 involved in anatomical structure development|apoptosis signaling involved in anatomical structure development|apoptosis involved in development of an anatomical structure|induction of apoptosis involved in anatomical structure development|apoptotic process involved in development of an anatomical structure|signaling (initiator) caspase activity involved in anatomical structure development|apoptotic programmed cell death involved in anatomical structure development						pr	2014-02-28T13:09:43Z						biological_process											owl:Class	
GO:1990183	biolink:NamedThing	lymphatic vascular process in circulatory system	A circulatory process that occurs at the level of the lymphatic vasculature.	got7fsn_ti							sl	2013-09-10T22:26:40Z						biological_process											owl:Class	
GO:0008107	biolink:NamedThing	galactoside 2-alpha-L-fucosyltransferase activity	Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R.	got7fsn_ti	guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase activity|secretor-type beta-galactoside alpha-1->2 fucosyltransferase activity|secretor-type beta-galactoside alpha1->2 fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase activity|guanosine diphosphofucose-galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase activity|alpha-2-fucosyltransferase activity|alpha(1,2)-L-fucosyltransferase activity|alpha-(1->2)-L-fucosyltransferase activity|guanosine diphosphofucose-lactose fucosyltransferase activity|H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase activity|GDP fucose-lactose fucosyltransferase activity|galactoside 2-L-fucosyltransferase activity|blood-group substance H-dependent fucosyltransferase activity|blood group H alpha-2-fucosyltransferase activity|GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase activity|beta-galactoside alpha1->2 fucosyltransferase activity|H-gene-encoded beta-galactoside alpha1->2 fucosyltransferase activity|beta-galactoside alpha-1->2 fucosyltransferase activity|GDP-L-fucose:lactose fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase activity|guanosine diphosphofucose-galactoside 2-L-fucosyltransferase activity|alpha-2-L-fucosyltransferase activity|guanosine diphospho-L-fucose-lactose fucosyltransferase activity|guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl-glucosylceramide alpha-L-fucosyltransferase activity											Reactome:R-HSA-9603983|Reactome:R-HSA-9603982|MetaCyc:GALACTOSIDE-2-L-FUCOSYLTRANSFERASE-RXN|RHEA:50664|Reactome:R-HSA-9036987|EC:2.4.1.69		molecular_function											owl:Class	
GO:0042206	biolink:NamedThing	halogenated hydrocarbon catabolic process	The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms.	got7fsn_ti	halogenated hydrocarbon breakdown|halogenated hydrocarbon degradation|halogenated hydrocarbon catabolism													biological_process											owl:Class	
GO:0102613	biolink:NamedThing	trimethyluric acid monooxygenase activity	Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ <=> 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O.	got7fsn_ti												RHEA:48992|MetaCyc:RXN-15454		molecular_function											owl:Class	
GO:0039683	biolink:NamedThing	rolling circle double-stranded viral DNA replication	A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.	got7fsn_ti	dsDNA rolling circle replication						bf	2013-10-17T14:15:04Z				VZ:2676		biological_process											owl:Class	
GO:0047634	biolink:NamedThing	agmatine N4-coumaroyltransferase activity	Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H(+).	got7fsn_ti	4-coumaroyl-CoA:agmatine N4-coumaroyltransferase activity|agmatine coumaroyltransferase activity|p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase activity|4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase activity											RHEA:13405|EC:2.3.1.64|MetaCyc:AGMATINE-N4-COUMAROYLTRANSFERASE-RXN|KEGG_REACTION:R01617		molecular_function											owl:Class	
GO:0060139	biolink:NamedThing	positive regulation of apoptotic process by virus	Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process.	got7fsn_ti	positive regulation of apoptosis by virus													biological_process											owl:Class	
GO:0008456	biolink:NamedThing	alpha-N-acetylgalactosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides.	got7fsn_ti	N-acetyl-alpha-galactosaminidase activity|N-acetyl-alpha-D-galactosaminidase activity|alpha-NAGA activity|alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity|alpha-galactosidase B activity|alpha-acetylgalactosaminidase activity											MetaCyc:3.2.1.49-RXN|EC:3.2.1.49|RHEA:15085		molecular_function											owl:Class	
GO:0003925	biolink:NamedThing	G protein activity	A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).	got7fsn_ti	signaling G protein activity|large G-protein GTPase activity|large G-protein activity|small monomeric G protein activity|heterotrimeric G-protein GTPase activity|small monomeric GTPase activity	https://github.com/geneontology/go-ontology/issues/19082									GO:0003927	EC:3.6.5.1|MetaCyc:3.6.1.47-RXN|MetaCyc:3.6.1.46-RXN|EC:3.6.5.2		molecular_function											owl:Class	
GO:0102292	biolink:NamedThing	30-hydroxy-beta-amyrin 11-hydroxylase activity	Catalysis of the reaction: 30-hydroxy-beta-amyrin + O2 + NADPH + H+ <=> 11alpha,30-dihydroxy-beta-amyrin + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-12683		molecular_function											owl:Class	
GO:0038039	biolink:NamedThing	G protein-coupled receptor heterodimeric complex	A protein complex that contains two G protein-coupled receptors (GPCRs) of different subtypes. Formation of a GPCR heterodimer may alter the functional property of the GPCR.	got7fsn_ti	GPCR heterodimer|G-protein coupled receptor heterodimer|G-protein coupled receptor heterodimeric complex						bf	2011-11-02T04:44:20Z						cellular_component											owl:Class	
GO:0071045	biolink:NamedThing	nuclear histone mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus.	got7fsn_ti							krc	2009-07-30T09:52:44Z						biological_process											owl:Class	
GO:0120299	biolink:NamedThing	peptide histaminyltransferase activity	Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20685					krc	2021-01-19T03:23:48Z				RHEA:66564		molecular_function											owl:Class	
GO:0050689	biolink:NamedThing	negative regulation of defense response to virus by host	Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	downregulation of antiviral response by host|negative regulation by host of antiviral response|down-regulation of antiviral response by host|negative regulation of antiviral response by host|down regulation of antiviral response by host|inhibition of antiviral response by host													biological_process											owl:Class	
GO:0031553	biolink:NamedThing	positive regulation of brain-derived neurotrophic factor-activated receptor activity	Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.	got7fsn_ti	upregulation of brain-derived neurotrophic factor receptor activity|up-regulation of brain-derived neurotrophic factor receptor activity|up regulation of brain-derived neurotrophic factor receptor activity|stimulation of brain-derived neurotrophic factor receptor activity|positive regulation of brain-derived neurotrophic factor receptor activity|positive regulation of BDNF receptor activity|activation of brain-derived neurotrophic factor receptor activity													biological_process											owl:Class	
GO:0031550	biolink:NamedThing	positive regulation of brain-derived neurotrophic factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.	got7fsn_ti	positive regulation of BDNF receptor signalling pathway|upregulation of brain-derived neurotrophic factor receptor signaling pathway|stimulation of brain-derived neurotrophic factor receptor signaling pathway|positive regulation of brain-derived neurotrophic factor receptor signalling pathway|activation of brain-derived neurotrophic factor receptor signaling pathway|positive regulation of BDNF receptor signaling pathway|up regulation of brain-derived neurotrophic factor receptor signaling pathway|up-regulation of brain-derived neurotrophic factor receptor signaling pathway													biological_process											owl:Class	
GO:0021851	biolink:NamedThing	neuroblast division in dorsal lateral ganglionic eminence	The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.	got7fsn_ti														biological_process											owl:Class	
GO:0021848	biolink:NamedThing	neuroblast division in subpallium	The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.	got7fsn_ti	neuroblast division in the ventral telencephalon													biological_process											owl:Class	
GO:0046222	biolink:NamedThing	aflatoxin metabolic process	The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.	got7fsn_ti	aflatoxin B2 metabolic process|aflatoxin B1 metabolism|aflatoxin B metabolic process|aflatoxin metabolism|aflatoxin B2 metabolism|aflatoxin B1 metabolic process	https://github.com/geneontology/go-ontology/issues/18291									GO:0043390|GO:0043391|GO:0043389			biological_process											owl:Class	
GO:0047931	biolink:NamedThing	glucosamine kinase activity	Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate.	got7fsn_ti	ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase activity|aminodeoxyglucose kinase activity|glucosamine kinase (phosphorylating)|ATP:D-glucosamine phosphotransferase activity											EC:2.7.1.8|MetaCyc:GLUCOSAMINE-KINASE-RXN|RHEA:10948		molecular_function											owl:Class	
GO:0031648	biolink:NamedThing	protein destabilization	Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.	got7fsn_ti	protein destabilisation|negative regulation of protein stability													biological_process											owl:Class	
GO:0044205	biolink:NamedThing	'de novo' UMP biosynthetic process	The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.	got7fsn_ti	'de novo' UMP biosynthesis						jl	2009-10-21T11:27:31Z						biological_process											owl:Class	
GO:0060499	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in lung induction	The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.	got7fsn_ti	fibroblast growth factor receptor signalling pathway involved in lung induction													biological_process											owl:Class	
GO:0035096	biolink:NamedThing	larval midgut cell programmed cell death	The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.	got7fsn_ti	larval midgut cell death|programmed cell death of larval midgut cells													biological_process											owl:Class	
GO:0071885	biolink:NamedThing	N-terminal protein N-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.	got7fsn_ti	X-Pro-Lys N-terminal methyltransferase						mah	2010-09-13T04:53:57Z						molecular_function											owl:Class	
GO:0005905	biolink:NamedThing	clathrin-coated pit	A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.	got7fsn_ti	coated pit											NIF_Subcellular:sao1969557946		cellular_component											owl:Class	
GO:0019145	biolink:NamedThing	aminobutyraldehyde dehydrogenase activity	Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+.	got7fsn_ti	4-aminobutanal dehydrogenase activity|ABAL dehydrogenase activity|4-aminobutanal:NAD+ 1-oxidoreductase activity|4-aminobutyraldehyde dehydrogenase activity|gamma-aminobutyraldehyde dehydroganase activity											EC:1.2.1.19|RHEA:19105|MetaCyc:AMINOBUTDEHYDROG-RXN		molecular_function											owl:Class	
GO:0062129	biolink:NamedThing	chitin-based extracellular matrix	Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet.	got7fsn_ti	chitin-based ECM						dph	2019-06-13T12:57:13Z						cellular_component											owl:Class	
GO:0010918	biolink:NamedThing	positive regulation of mitochondrial membrane potential	Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	got7fsn_ti	elevation of mitochondrial membrane potential													biological_process											owl:Class	
GO:0034653	biolink:NamedThing	retinoic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.	got7fsn_ti	vitamin A1 acid catabolic process|retinoic acid catabolism|retinoic acid degradation|retinoic acid breakdown													biological_process											owl:Class	
GO:0060679	biolink:NamedThing	trifid subdivision of terminal units involved in ureteric bud branching	The process in which a ureteric bud splits into three units at its end.	got7fsn_ti							dph	2009-06-02T02:37:42Z						biological_process											owl:Class	
GO:0003960	biolink:NamedThing	NADPH:quinone reductase activity	Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.	got7fsn_ti	zeta-crystallin activity|NADPH:quinone oxidoreductase activity|quinone oxidoreductase activity											EC:1.6.5.5|RHEA:14269|MetaCyc:QOR-RXN|Reactome:R-HSA-6799722		molecular_function											owl:Class	
GO:0043769	biolink:NamedThing	Tpg-containing telomere binding complex	A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species.	got7fsn_ti	telomere complex													cellular_component											owl:Class	
GO:0004040	biolink:NamedThing	amidase activity	Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.	got7fsn_ti	acetamidase activity|acylamidase activity|fatty acylamidase activity|acylamide amidohydrolase activity|acylase activity|N-acetylaminohydrolase activity|amidohydrolase activity											UM-BBD_enzymeID:e0068|MetaCyc:AMIDASE-RXN|RHEA:12020|EC:3.5.1.4		molecular_function											owl:Class	
GO:0050975	biolink:NamedThing	sensory perception of touch	The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).	got7fsn_ti	tactile sense|taction|tactition|perception of touch											Wikipedia:Touch		biological_process											owl:Class	
GO:0071633	biolink:NamedThing	dihydroceramidase activity	Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine.	got7fsn_ti							mah	2010-02-11T04:24:12Z						molecular_function											owl:Class	
GO:0047982	biolink:NamedThing	homocysteine desulfhydrase activity	Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate.	got7fsn_ti	L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)|L-homocysteine hydrogen-sulfide-lyase (deaminating)|homocysteine desulfurase activity											Reactome:R-HSA-1614631|MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN|RHEA:14501|EC:4.4.1.2		molecular_function											owl:Class	
GO:0051086	biolink:NamedThing	chaperone mediated protein folding independent of cofactor	The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release.	got7fsn_ti	chaperone cofactor-independent protein folding													biological_process											owl:Class	
GO:0001514	biolink:NamedThing	selenocysteine incorporation	The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.	got7fsn_ti												RESID:AA0022		biological_process											owl:Class	
GO:0110087	biolink:NamedThing	suppression by virus of host protease activator activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protease activator activity.	got7fsn_ti							kmv	2018-02-12T20:17:29Z						biological_process											owl:Class	
GO:0032530	biolink:NamedThing	regulation of microvillus organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus.	got7fsn_ti	regulation of microvillus organization and biogenesis|regulation of microvillus organisation													biological_process											owl:Class	
GO:0035314	biolink:NamedThing	scab formation	Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.	got7fsn_ti														biological_process											owl:Class	
GO:0009673	biolink:NamedThing	low-affinity phosphate transmembrane transporter activity	Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low affinity phosphate transmembrane transporter activity													molecular_function											owl:Class	
GO:0090537	biolink:NamedThing	CERF complex	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters.	got7fsn_ti							tb	2013-02-11T14:07:14Z						cellular_component											owl:Class	
GO:0008768	biolink:NamedThing	UDP-sugar diphosphatase activity	Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate.	got7fsn_ti	UDP-sugar sugarphosphohydrolase activity|UDP-sugar pyrophosphatase activity|nucleosidediphosphate-sugar pyrophosphatase activity|nucleosidediphosphate-sugar diphosphatase activity|UDP-sugar hydrolase activity											Reactome:R-HSA-6810464|MetaCyc:UDPSUGARHYDRO-RXN|EC:3.6.1.45		molecular_function											owl:Class	
GO:0098981	biolink:NamedThing	cholinergic synapse	A synapse that uses acetylcholine as a neurotransmitter.	got7fsn_ti														cellular_component											owl:Class	
GO:0003721	biolink:NamedThing	telomerase RNA reverse transcriptase activity	Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template.	got7fsn_ti	telomerase, catalyst													molecular_function											owl:Class	
GO:0062046	biolink:NamedThing	dehydropipecolic acid reductase	Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+.	got7fsn_ti							dph	2018-05-11T12:16:00Z						molecular_function											owl:Class	
GO:0006316	biolink:NamedThing	movement of group I intron	Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction.	got7fsn_ti														biological_process											owl:Class	
GO:0070066	biolink:NamedThing	cellubrevin-VAMP4-endobrevin-syntaxin-6 complex	A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).	got7fsn_ti	SNARE complex (Vamp3, Vamp4, Vam8, Stx6)|Vamp3-Vamp4-Vam8-Stx6 complex													cellular_component											owl:Class	
GO:0010597	biolink:NamedThing	green leaf volatile biosynthetic process	The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0019372	biolink:NamedThing	lipoxygenase pathway	The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.	got7fsn_ti														biological_process											owl:Class	
GO:0050560	biolink:NamedThing	aspartate-tRNA(Asn) ligase activity	Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP.	got7fsn_ti	nondiscriminating aspartyl-tRNA synthetase activity|L-aspartate:tRNAAsx ligase (AMP-forming)|aspartate-tRNAAsn ligase activity											MetaCyc:6.1.1.23-RXN|RHEA:18349|EC:6.1.1.23		molecular_function											owl:Class	
GO:0003746	biolink:NamedThing	translation elongation factor activity	Functions in chain elongation during polypeptide synthesis at the ribosome.	got7fsn_ti											GO:0008182|GO:0008183	Reactome:R-HSA-192704|Reactome:R-HSA-192841		molecular_function											owl:Class	
GO:0004143	biolink:NamedThing	diacylglycerol kinase activity	Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.	got7fsn_ti	diglyceride kinase activity|arachidonoyl-specific diacylglycerol kinase activity|1,2-diacylglycerol kinase activity|sn-1,2-diacylglycerol kinase activity|DG kinase activity|CTP:diacylglycerol kinase activity|DGK activity|diacylglycerol:ATP kinase activity|ATP:diacylglycerol phosphotransferase activity|ATP:1,2-diacylglycerol 3-phosphotransferase activity|1,2-diacylglycerol kinase (phosphorylating)											RHEA:10272|MetaCyc:DIACYLGLYKIN-RXN|EC:2.7.1.107|Reactome:R-HSA-426240		molecular_function											owl:Class	
GO:0038096	biolink:NamedThing	Fc-gamma receptor signaling pathway involved in phagocytosis	An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.	got7fsn_ti	Fc-gamma receptor signalling pathway involved in phagocytosis|Fc gamma receptor-dependent phagocytosis|IgG-mediated phagocytosis|Fcgamma receptor-mediated phagocytosis						bf	2012-02-16T05:26:25Z						biological_process											owl:Class	
GO:0002749	biolink:NamedThing	antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen	Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR).	got7fsn_ti	antigen processing and presentation initiated by TLR mediated phagocytosis of antigen													biological_process											owl:Class	
GO:0002747	biolink:NamedThing	antigen processing and presentation following phagocytosis	Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0002470	biolink:NamedThing	plasmacytoid dendritic cell antigen processing and presentation	The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0004487	biolink:NamedThing	methylenetetrahydrofolate dehydrogenase (NAD+) activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.	got7fsn_ti	5,10-methylenetetrahydrofolate dehydrogenase activity|5,10-methylenetetrahydrofolate:NAD+ oxidoreductase											KEGG_REACTION:R01218|Reactome:R-HSA-6801462|MetaCyc:1.5.1.15-RXN|RHEA:22892|EC:1.5.1.15		molecular_function											owl:Class	
GO:1902298	biolink:NamedThing	cell cycle DNA replication maintenance of fidelity	Any maintenance of fidelity that is involved in cell cycle DNA replication.	got7fsn_ti	maintenance of fidelity involved in cell cycle DNA replication|maintenance of fidelity during DNA-dependent DNA replication involved in cell cycle DNA replication						jl	2013-07-10T11:47:19Z						biological_process											owl:Class	
GO:0030431	biolink:NamedThing	sleep	Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.	got7fsn_ti	diapause|lethargus|dormancy											Wikipedia:Sleep		biological_process											owl:Class	
GO:0030275	biolink:NamedThing	LRR domain binding	Binding to a LRR domain (leucine rich repeats) of a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0048085	biolink:NamedThing	adult chitin-containing cuticle pigmentation	Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster.	got7fsn_ti	adult cuticle pigmentation										GO:0048068			biological_process											owl:Class	
GO:0140262	biolink:NamedThing	mRNA cap binding complex binding	Binding to a mRNA cap binding complex.	got7fsn_ti							pg	2018-09-12T12:56:16Z						molecular_function											owl:Class	
GO:0032809	biolink:NamedThing	neuronal cell body membrane	The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.	got7fsn_ti	neuronal cell soma membrane|neuron cell body membrane													cellular_component											owl:Class	
GO:0030020	biolink:NamedThing	extracellular matrix structural constituent conferring tensile strength	A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress.	got7fsn_ti	core matrisome|core extracellular matrix				Extracellular matrix collagen proteins may be annotated to this term. PMID:29632050, PMID:24443019									molecular_function											owl:Class	
GO:0018040	biolink:NamedThing	C-terminal peptidyl-glutamic acid amidation	The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0087		biological_process											owl:Class	
GO:0015693	biolink:NamedThing	magnesium ion transport	The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	magnesium transport													biological_process											owl:Class	
GO:0004476	biolink:NamedThing	mannose-6-phosphate isomerase activity	Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.	got7fsn_ti	phosphohexoisomerase activity|D-mannose-6-phosphate aldose-ketose-isomerase activity|D-mannose-6-phosphate ketol-isomerase activity|phosphohexomutase activity|phosphomannoisomerase activity|phosphomannose isomerase activity|mannose phosphate isomerase activity											EC:5.3.1.8|MetaCyc:MANNPISOM-RXN|RHEA:12356|Reactome:R-HSA-3781832|Reactome:R-HSA-532549		molecular_function											owl:Class	
GO:0106015	biolink:NamedThing	negative regulation of inflammatory response to wounding	Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.	got7fsn_ti							hjd	2017-04-28T20:09:46Z						biological_process											owl:Class	
GO:0106014	biolink:NamedThing	regulation of inflammatory response to wounding	Any process that modulates the frequency, rate or extent of the inflammatory response to wounding.	got7fsn_ti							hjd	2017-04-28T20:03:14Z						biological_process											owl:Class	
GO:0021672	biolink:NamedThing	rhombomere 7 structural organization	The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti	rhombomere 7 structural organisation													biological_process											owl:Class	
GO:0031959	biolink:NamedThing	mineralocorticoid receptor signaling pathway	Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor.	got7fsn_ti	mineralocorticoid receptor signalling pathway													biological_process											owl:Class	
GO:0140432	biolink:NamedThing	5'-hydroxyl dinucleotide hydrolase	Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-RNA + H20 = 5'OH-NpN (dinucleotide) + 5'P-RNA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18881					pg	2020-02-19T05:50:35Z						molecular_function											owl:Class	
GO:0010846	biolink:NamedThing	activation of reciprocal meiotic recombination	Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti	activation of meiotic recombination													biological_process											owl:Class	
GO:0042564	biolink:NamedThing	NLS-dependent protein nuclear import complex	A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore.	got7fsn_ti														cellular_component											owl:Class	
GO:0106016	biolink:NamedThing	positive regulation of inflammatory response to wounding	Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.	got7fsn_ti							hjd	2017-04-28T20:16:31Z						biological_process											owl:Class	
GO:0034569	biolink:NamedThing	monodemethylisoproturon dehydrogenase activity	Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0893|EC:1.17.99.-		molecular_function											owl:Class	
GO:0004360	biolink:NamedThing	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.	got7fsn_ti	glucosamine 6-phosphate synthase activity|glucosaminephosphate isomerase|L-glutamine:D-fructose-6-phosphate isomerase (deaminating)|glucosamine-6-phosphate synthase activity|L-glutamine-D-fructose-6-phosphate amidotransferase activity|GlcN6P synthase activity|D-fructose-6-phosphate amidotransferase activity|glucosamine--fructose-6-phosphate aminotransferase (isomerizing) activity|hexosephosphate aminotransferase activity|glucosamine-6-phosphate isomerase (glutamine-forming) activity											MetaCyc:L-GLN-FRUCT-6-P-AMINOTRANS-RXN|RHEA:13237|EC:2.6.1.16|Reactome:R-HSA-449715|KEGG_REACTION:R00768|Reactome:R-HSA-4085027		molecular_function											owl:Class	
GO:0016338	biolink:NamedThing	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.	got7fsn_ti	calcium-independent cell adhesion molecule activity													biological_process											owl:Class	
GO:0052683	biolink:NamedThing	(Z)-gamma-bisabolene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.	got7fsn_ti	(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(Z)-gamma-bisabolene-forming] activity											MetaCyc:RXN-10005|RHEA:26081|EC:4.2.3.40		molecular_function											owl:Class	
GO:0071977	biolink:NamedThing	bacterial-type flagellum-dependent swimming motility	Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium.	got7fsn_ti	bacterial-type flagellum-mediated cell swimming|bacterial-type flagellar swimming motility						mah	2010-10-21T02:58:51Z						biological_process											owl:Class	
GO:0071975	biolink:NamedThing	cell swimming	Cell motility that results in the smooth movement of a cell through a liquid medium.	got7fsn_ti	cell swimming motility						mah	2010-10-21T02:31:34Z						biological_process											owl:Class	
GO:0031721	biolink:NamedThing	hemoglobin alpha binding	Binding to a hemoglobin alpha chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0030492	biolink:NamedThing	hemoglobin binding	Binding to hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	got7fsn_ti	haemoglobin binding|globin binding													molecular_function											owl:Class	
GO:0042629	biolink:NamedThing	mast cell granule	Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase.	got7fsn_ti														cellular_component											owl:Class	
GO:0036508	biolink:NamedThing	protein alpha-1,2-demannosylation	The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.	got7fsn_ti	mannose trimming|glycoprotein mannose trimming				Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T13:58:50Z						biological_process											owl:Class	
GO:0034888	biolink:NamedThing	endosulfan monooxygenase I activity	Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O.	got7fsn_ti												UM-BBD_reactionID:r1382		molecular_function											owl:Class	
GO:0030512	biolink:NamedThing	negative regulation of transforming growth factor beta receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.	got7fsn_ti	negative regulation of TGF-beta receptor signaling pathway|negative regulation of TGFbeta receptor signaling pathway|down regulation of transforming growth factor beta receptor signaling pathway|downregulation of transforming growth factor beta receptor signaling pathway|inhibition of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signalling pathway|down-regulation of transforming growth factor beta receptor signaling pathway													biological_process											owl:Class	
GO:0009652	biolink:NamedThing	thigmotropism	The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it.	got7fsn_ti												Wikipedia:Thigmotropism		biological_process											owl:Class	
GO:0004412	biolink:NamedThing	homoserine dehydrogenase activity	Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.	got7fsn_ti												EC:1.1.1.3|RHEA:15761|MetaCyc:HOMOSERDEHYDROG-RXN		molecular_function											owl:Class	
GO:0009949	biolink:NamedThing	polarity specification of anterior/posterior axis	Any process resulting in the establishment of polarity along the anterior/posterior axis.	got7fsn_ti														biological_process											owl:Class	
GO:0018016	biolink:NamedThing	N-terminal peptidyl-proline dimethylation	The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.	got7fsn_ti												RESID:AA0066		biological_process											owl:Class	
GO:0102125	biolink:NamedThing	gibberellin A9 16alpha,17 epoxidase activity	Catalysis of the reaction: gibberellin A9 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A9 + H2O + NAD(P).	got7fsn_ti												MetaCyc:RXN-11388		molecular_function											owl:Class	
GO:0031773	biolink:NamedThing	kisspeptin receptor binding	Binding to a kisspeptin receptor.	got7fsn_ti	hypogonadotropin-1 receptor binding|metastin receptor binding|kisspeptin receptor ligand|G-protein coupled receptor 54 binding|hOT7T175 receptor binding|KiSS-1 receptor binding													molecular_function											owl:Class	
GO:1902408	biolink:NamedThing	mitotic cytokinesis, site selection	Any cytokinesis, site selection that is involved in mitotic cell cycle.	got7fsn_ti	site selection involved in cytokinesis involved in mitotic cell cycle|site selection involved in cell cycle cytokinesis involved in mitotic cell cycle						jl	2013-09-12T12:29:13Z						biological_process											owl:Class	
GO:0060215	biolink:NamedThing	primitive hemopoiesis	A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.	got7fsn_ti	primitive hematopoiesis|primitive haemopoiesis|primitive haematopoiesis													biological_process											owl:Class	
GO:0018008	biolink:NamedThing	N-terminal peptidyl-glycine N-myristoylation	The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine.	got7fsn_ti	N-terminal peptidyl-glycine N-myristylation											RESID:AA0059		biological_process											owl:Class	
GO:0102354	biolink:NamedThing	11-cis-retinol dehydrogenase activity	Catalysis of the reaction: 11-cis-retinol + NADP = 11-cis-retinal + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13363|RHEA:54912		molecular_function											owl:Class	
GO:0019929	biolink:NamedThing	peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid	The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid.	got7fsn_ti												RESID:AA0315		biological_process											owl:Class	
GO:0032640	biolink:NamedThing	tumor necrosis factor production	The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.	got7fsn_ti	TNF production|tumor necrosis factor biosynthetic process|TNF-alpha production|tumor necrosis factor synthesis|tumor necrosis factor formation|cachectin production|TNF biosynthesis|tumor necrosis factor anabolism|Tnfa production|tumor necrosis factor secretion|tumor necrosis factor-alpha production|TNF-alpha biosynthetic process|tumor necrosis factor biosynthesis|TNF biosynthetic process|TNF alpha biosynthesis|TNF-alpha biosynthesis				Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). That this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		sl	2015-06-15T22:59:26Z			GO:0042533|GO:1990774			biological_process											owl:Class	
GO:0044672	biolink:NamedThing	acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex	A multifunctional enzyme complex composed of five different polypeptides that catalyzes the decarbonylation of acetyl-CoA, cleaves the C-C and C-S bonds in the acetyl moiety of acetyl-CoA, oxidizes the carbonyl group to CO2 and transfers the methyl group to tetrahydrosarcinapterin. These reactions are important for methanogenesis.	got7fsn_ti	CO dehydrogenase complex|carbon-monoxide:(acceptor) oxidoreductase complex|carbon monoxide dehydrogenase|CODH/ACS complex|CODH|CO dehydrogenase/acetyl-CoA synthase complex						jl	2012-08-08T16:06:03Z						cellular_component											owl:Class	
GO:0003711	biolink:NamedThing	transcription elongation regulator activity	A molecular function that regulates transcriptional elongation by enabling the transition from transcription initiation to elongation or by altering the elongation properties of the enzyme during the elongation phase of transcription.	got7fsn_ti	transcriptional elongation regulator activity|transcription elongation regulator activity|transcription elongation factor activity	https://github.com/geneontology/go-ontology/issues/14398			Restored term from obsolete.									molecular_function											owl:Class	
GO:0014012	biolink:NamedThing	peripheral nervous system axon regeneration	The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.	got7fsn_ti	axon regeneration in peripheral nervous system													biological_process											owl:Class	
GO:0047784	biolink:NamedThing	cortisol O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate.	got7fsn_ti	cortisol acetyltransferase activity|corticosteroid acetyltransferase activity|acetyl-CoA:cortisol O-acetyltransferase activity|corticosteroid-21-O-acetyltransferase activity											MetaCyc:CORTISOL-O-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R02837|RHEA:17073|EC:2.3.1.27		molecular_function											owl:Class	
GO:0051915	biolink:NamedThing	induction of synaptic plasticity by chemical substance	The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require.	got7fsn_ti	activation of synaptic plasticity by drug|activation of synaptic plasticity by chemical substance|induction of synaptic plasticity by drug													biological_process											owl:Class	
GO:0051914	biolink:NamedThing	positive regulation of synaptic plasticity by chemical substance	The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require.	got7fsn_ti	stimulation of synaptic plasticity by chemical substance|positive regulation of synaptic plasticity by drug|up-regulation of synaptic plasticity by chemical substance|up regulation of synaptic plasticity by chemical substance|activation of synaptic plasticity by chemical substance|upregulation of synaptic plasticity by chemical substance													biological_process											owl:Class	
GO:0103001	biolink:NamedThing	dimethylsulfoxide oxygenase activity	Catalysis of the reaction: dimethyl sulfoxide + O2 + NADPH + H+ <=> sulfonyldimethane + H2O + NADP.	got7fsn_ti												RHEA:57956|MetaCyc:RXN-9767		molecular_function											owl:Class	
GO:0103046	biolink:NamedThing	alanylglutamate dipeptidase activity	Catalysis of the reaction: L-alanyl-L-glutamate + H2O <=> L-alanine + L-glutamate.	got7fsn_ti												MetaCyc:RXN0-6981|EC:3.4.13.18		molecular_function											owl:Class	
GO:0000210	biolink:NamedThing	NAD+ diphosphatase activity	Catalysis of the reaction: NAD+ + H2O = AMP + NMN.	got7fsn_ti	NADH pyrophosphatase activity|NADP pyrophosphatase activity|NAD diphosphatase activity|NAD+ pyrophosphatase activity|NAD pyrophosphatase activity|NAD(+) pyrophosphatase activity|NAD+ phosphohydrolase activity|nicotinamide adenine dinucleotide pyrophosphatase activity											MetaCyc:NADPYROPHOSPHAT-RXN|EC:3.6.1.22|RHEA:11800		molecular_function											owl:Class	
GO:0017098	biolink:NamedThing	sulfonylurea receptor binding	Binding to a sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel.	got7fsn_ti	sulfonylurea receptor ligand|sulphonylurea receptor binding													molecular_function											owl:Class	
GO:0046405	biolink:NamedThing	glycerol dehydratase activity	Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O.	got7fsn_ti	glycerol hydro-lyase activity|glycerol dehydrase activity|glycerol hydro-lyase (3-hydroxypropanal-forming)											MetaCyc:GLYCEROL-DEHYDRATASE-RXN|EC:4.2.1.30|RHEA:19765		molecular_function											owl:Class	
GO:0004740	biolink:NamedThing	pyruvate dehydrogenase (acetyl-transferring) kinase activity	Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate.	got7fsn_ti	PDK|PDH kinase activity|pyruvate dehydrogenase kinase activity|pyruvate dehydrogenase kinase (phosphorylating) activity|PDHK											Reactome:R-HSA-203946|EC:2.7.11.2|RHEA:23052|MetaCyc:2.7.11.2-RXN		molecular_function											owl:Class	
GO:0045156	biolink:NamedThing	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis.	got7fsn_ti	cytochrome bc1 complex|cytochrome													molecular_function											owl:Class	
GO:0030273	biolink:NamedThing	melanin-concentrating hormone receptor activity	Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity.	got7fsn_ti	MCH receptor													molecular_function											owl:Class	
GO:0004957	biolink:NamedThing	prostaglandin E receptor activity	Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity.	got7fsn_ti	PGE receptor activity|PGE(2) receptor activity													molecular_function											owl:Class	
GO:0102485	biolink:NamedThing	dATP phosphohydrolase activity	Catalysis of the reaction: dATP + 2 H2O = dAMP + 2 hydrogenphosphate + 2 H+.	got7fsn_ti												EC:3.6.1.5|MetaCyc:RXN-14195		molecular_function											owl:Class	
GO:0018388	biolink:NamedThing	N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine	The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine.	got7fsn_ti												RESID:AA0275		biological_process											owl:Class	
GO:0098608	biolink:NamedThing	methylselenol demethylase activity	Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH.	got7fsn_ti							dos	2014-04-16T11:28:00Z				Reactome:R-HSA-2408530		molecular_function											owl:Class	
GO:0006428	biolink:NamedThing	isoleucyl-tRNA aminoacylation	The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0050626	biolink:NamedThing	trimethylamine-N-oxide reductase (cytochrome c) activity	Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+.	got7fsn_ti	trimethylamine:cytochrome c oxidoreductase activity|TOR activity|TMAO reductase activity											MetaCyc:1.7.2.3-RXN|EC:1.7.2.3|RHEA:24236|Wikipedia:Trimethylamine_N-oxide_reductase		molecular_function											owl:Class	
GO:0018769	biolink:NamedThing	2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate.	got7fsn_ti												UM-BBD_reactionID:r0311		molecular_function											owl:Class	
GO:0070691	biolink:NamedThing	P-TEFb complex	A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T.	got7fsn_ti	Bur1/Bur2 complex|cyclin-dependent kinase 9 (Cdk9)-cyclin T2 complex|dimeric positive transcription elongation factor complex b|cyclin-dependent kinase 9 (Cdk9)-cyclin T1 complex|Sgv1/Bur2 complex						mah	2009-06-03T03:12:56Z						cellular_component											owl:Class	
GO:0052844	biolink:NamedThing	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity	Catalysis of the reaction: inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.	got7fsn_ti							ai	2011-12-05T10:59:26Z				MetaCyc:RXN-10978		molecular_function											owl:Class	
GO:0090445	biolink:NamedThing	positive regulation of nematode larval development, heterochronic	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached.	got7fsn_ti							tb	2012-08-24T13:24:43Z						biological_process											owl:Class	
GO:0017041	biolink:NamedThing	galactosylgalactosylglucosylceramidase activity	Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose.	got7fsn_ti	D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase activity|trihexosylceramide alpha-galactosidase activity|ceramide trihexosidase activity|trihexosyl ceramide galactosidase activity|ceramidetrihexosidase activity|ceramidetrihexoside alpha-galactosidase activity											EC:3.2.1.47|MetaCyc:3.2.1.47-RXN|RHEA:21112		molecular_function											owl:Class	
GO:0055093	biolink:NamedThing	response to hyperoxia	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.	got7fsn_ti	response to increased oxygen tension|response to hyperoxic stress													biological_process											owl:Class	
GO:0052591	biolink:NamedThing	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8.	got7fsn_ti					Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591.							RHEA:28751|MetaCyc:GLYC3PDEHYDROG-RXN|EC:1.1.5.3		molecular_function											owl:Class	
GO:0042786	biolink:NamedThing	evasion of host immune response via regulation of host antigen processing and presentation	Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	active immune evasion via modulation of antigen processing/presentation|active immune evasion via regulation of antigen processing and presentation|active immune evasion via modulation of antigen processing and presentation|active evasion of immune response of other organism via regulation of antigen processing and presentation in other organism involved in symbiotic interaction|active evasion of host immune response via regulation of host antigen processing and presentation|active evasion of host immune response via regulation of host antigen processing and presentation pathway										GO:0051813			biological_process											owl:Class	
GO:0097471	biolink:NamedThing	mossy fiber rosette	A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes.	got7fsn_ti	cerebellar mossy fiber to granule cell synapse						pr	2013-02-21T07:42:52Z				NIF_Subcellular:nlx_subcell_091021		cellular_component											owl:Class	
GO:0002050	biolink:NamedThing	pyoverdine catabolic process	The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine.	got7fsn_ti														biological_process											owl:Class	
GO:0102373	biolink:NamedThing	uvaol dehydrogenase activity	Catalysis of the reaction: uvaol + NADPH + O2 + H+ <=> ursolic aldehyde + NADP + 2 H2O.	got7fsn_ti												EC:1.14.14.126|MetaCyc:RXN-13501		molecular_function											owl:Class	
GO:0072061	biolink:NamedThing	inner medullary collecting duct development	The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.	got7fsn_ti							mah	2010-01-25T04:08:45Z						biological_process											owl:Class	
GO:0098756	biolink:NamedThing	response to interleukin-21	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.	got7fsn_ti	response to IL-21													biological_process											owl:Class	
GO:0106151	biolink:NamedThing	CNBH domain intrinsic ligand binding	Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide.	got7fsn_ti					It is unclear if the motif bound by CNBHD is a specific motif or just a beta sheet with the appropriate amino acids.		hjd	2018-09-18T20:47:35Z						molecular_function											owl:Class	
GO:0000834	biolink:NamedThing	inositol heptakisphosphate 6-kinase activity	Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0047185	biolink:NamedThing	N-acetylneuraminate 4-O-acetyltransferase activity	Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA.	got7fsn_ti	sialate O-acetyltransferase|acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase activity											EC:2.3.1.44|MetaCyc:2.3.1.44-RXN|RHEA:18305|KEGG_REACTION:R01806		molecular_function											owl:Class	
GO:0102862	biolink:NamedThing	1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity (SN2-18:3 forming)	Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor = 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8329|EC:1.14.19.25		molecular_function											owl:Class	
GO:0070702	biolink:NamedThing	inner mucus layer	The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria.	got7fsn_ti							mah	2009-06-08T02:38:55Z						cellular_component											owl:Class	
GO:0010590	biolink:NamedThing	regulation of septum digestion after cytokinesis	Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.	got7fsn_ti	regulation of cell separation following cytokinesis|regulation of cell separation after cytokinesis|regulation of mitotic cytokinetic cell separation										GO:1902467|GO:2001041			biological_process											owl:Class	
GO:0120113	biolink:NamedThing	cytoplasm to vacuole transport by the NVT pathway	A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe.	got7fsn_ti	protein localization by the NVT pathway|protein localization by the Nbr1-mediated vacuolar targeting pathway|cytoplasm-to-vacuole targeting|cytoplasm to vacuole targeting						krc	2017-11-03T16:07:55Z						biological_process											owl:Class	
GO:1990268	biolink:NamedThing	response to gold nanoparticle	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus.	got7fsn_ti							sl	2014-01-10T17:37:34Z						biological_process											owl:Class	
GO:0140523	biolink:NamedThing	GTPase-dependent fusogenic activity	A GTPase activity that mediates the joining two lipid bilayers to form a single membrane.	got7fsn_ti	membrane fusion GTPase activity	https://github.com/geneontology/go-ontology/issues/19942					pg	2020-09-24T09:49:40Z						molecular_function											owl:Class	
GO:0140522	biolink:NamedThing	fusogenic activity	The activity of joining two lipid bilayers to form a single membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19942					pg	2020-09-24T09:45:21Z						molecular_function											owl:Class	
GO:0140664	biolink:NamedThing	ATP-dependent DNA damage sensor activity	A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21662					pg	2021-06-19T16:37:21Z						molecular_function											owl:Class	
GO:0034526	biolink:NamedThing	2-methylnaphthalene hydroxylase activity	Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.	got7fsn_ti												UM-BBD_reactionID:r0788|EC:1.14.13.-		molecular_function											owl:Class	
GO:0036242	biolink:NamedThing	glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity	The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase.	got7fsn_ti	glutamate degradation via gamma aminobutyrate transaminase activity				While mammals only have 2-oxoglutarate-dependent GABA-transaminase, both 2-oxoglutarate-dependent and pyruvate-dependent GABA-transaminase activities have been detected in plants.		bf	2012-05-23T02:28:33Z				MetaCyc:PWY-4321|MetaCyc:PWY3O-210		biological_process											owl:Class	
GO:0045504	biolink:NamedThing	dynein heavy chain binding	Binding to a heavy chain of the dynein complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0036430	biolink:NamedThing	CMP kinase activity	Catalysis of the reaction: ATP + CMP = ADP + CDP.	got7fsn_ti							bf	2013-09-16T14:11:48Z				MetaCyc:RXN-11832|RHEA:11600|KEGG_REACTION:R00512		molecular_function											owl:Class	
GO:0036311	biolink:NamedThing	chitin disaccharide deacetylase activity	Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate.	got7fsn_ti	chitobiose amidohydrolase activity|chitin oligosaccharide deacetylase activity|chitin oligosaccharide amidohydrolase activity				In contrast to EC:3.5.1.41 (chitin deacetylase) this enzyme is specific for the chitin disaccharide.		bf	2012-08-15T15:18:09Z						molecular_function											owl:Class	
GO:0034199	biolink:NamedThing	activation of protein kinase A activity	Any process that initiates the activity of the inactive enzyme protein kinase A.	got7fsn_ti	protein kinase A activation													biological_process											owl:Class	
GO:0048109	biolink:NamedThing	peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water.	got7fsn_ti												RESID:AA0344		biological_process											owl:Class	
GO:0102677	biolink:NamedThing	campesterol,NADPH:oxygen oxidoreductase activity	Catalysis of the reaction: H+ + campesterol + O2 + NADPH <=> (22S)-22-hydroxycampesterol + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-4225		molecular_function											owl:Class	
GO:0032447	biolink:NamedThing	protein urmylation	Covalent attachment of the ubiquitin-like protein URM1 to another protein.	got7fsn_ti														biological_process											owl:Class	
GO:0010203	biolink:NamedThing	response to very low fluence red light stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec.	got7fsn_ti														biological_process											owl:Class	
GO:0047189	biolink:NamedThing	2,3-diaminopropionate N-oxalyltransferase activity	Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA.	got7fsn_ti	oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase activity|oxalyldiaminopropionate synthase activity|oxalyldiaminopropionic synthase activity|ODAP synthase activity|oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase activity|oxalyl-CoA:L-alpha,beta-diaminopropionic acid oxalyltransferase activity											EC:2.3.1.58|KEGG_REACTION:R04211|MetaCyc:2.3.1.58-RXN|RHEA:13465		molecular_function											owl:Class	
GO:0031995	biolink:NamedThing	insulin-like growth factor II binding	Binding to insulin-like growth factor II.	got7fsn_ti	IGF-II binding													molecular_function											owl:Class	
GO:0033852	biolink:NamedThing	thyroid-hormone transaminase activity	Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate.	got7fsn_ti	3,5-dinitrotyrosine transaminase activity|thyroid-hormone aminotransferase activity|L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase activity|3,5-dinitrotyrosine aminotransferase activity|thyroid hormone aminotransferase activity											EC:2.6.1.26|MetaCyc:THYROID-HORMONE-AMINOTRANSFERASE-RXN|RHEA:19133|KEGG_REACTION:R03952		molecular_function											owl:Class	
GO:0001987	biolink:NamedThing	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure	A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure.	got7fsn_ti														biological_process											owl:Class	
GO:0006168	biolink:NamedThing	adenine salvage	Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.	got7fsn_ti	adenine salvage pathway|adenine, hypoxanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0046084	biolink:NamedThing	adenine biosynthetic process	The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.	got7fsn_ti	adenine synthesis|adenine anabolism|adenine biosynthesis|adenine formation													biological_process											owl:Class	
GO:0021990	biolink:NamedThing	neural plate formation	The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0099520	biolink:NamedThing	ion antiporter activity involved in regulation of presynaptic membrane potential	Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.	got7fsn_ti	ion antiporter activity involved in regulation of pre-synaptic membrane potential													molecular_function											owl:Class	
GO:0047894	biolink:NamedThing	flavonol 3-sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H(+) + quercetin 3-sulfate.	got7fsn_ti	flavonol 3-sulphotransferase activity|3'-phosphoadenylyl-sulfate:quercetin 3-sulfotransferase activity											MetaCyc:FLAVONOL-3-SULFOTRANSFERASE-RXN|KEGG_REACTION:R02159|RHEA:13453|EC:2.8.2.25		molecular_function											owl:Class	
GO:0034812	biolink:NamedThing	9,10-dihydroxybenzo(a)pyrene dioxygenase activity	Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r1134		molecular_function											owl:Class	
GO:0102531	biolink:NamedThing	ecdysteroid-phosphate phosphatase activity	Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate = hydrogenphosphate + an ecdysteroid.	got7fsn_ti												RHEA:63576|MetaCyc:RXN-14734		molecular_function											owl:Class	
GO:0071198	biolink:NamedThing	Kv4.1-DPP6 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.	got7fsn_ti	Kv4.1-DPPX channel complex						mah	2009-11-23T05:14:37Z				CORUM:600		cellular_component											owl:Class	
GO:0019518	biolink:NamedThing	L-threonine catabolic process to glycine	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine.	got7fsn_ti	L-threonine catabolism to glycine|L-threonine degradation to glycine|L-threonine catabolic process to pyruvate|threonine catabolic process to glycine|L-threonine breakdown to glycine											MetaCyc:THREONINE-DEG2-PWY		biological_process											owl:Class	
GO:0021650	biolink:NamedThing	vestibulocochlear nerve formation	The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	got7fsn_ti	CN VII formation													biological_process											owl:Class	
GO:0046589	biolink:NamedThing	ribonuclease T1 activity	Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates.	got7fsn_ti	RNase G|RNase Sa|RNase T1|ribonuclease Ch|binase activity|RNase T1 activity|RNase N1 activity|ribonuclease C2|ribonuclease N3|ribonuclease F1|ribonuclease PP1|ribonuclease N1|guanyloribonuclease activity|guanyl-specific RNase activity|Aspergillus oryzae ribonuclease activity|ribonuclease guaninenucleotido-2'-transferase (cyclizing)|RNase F1|ribonuclease U1|RNase N2 activity|ribonuclease SA											EC:4.6.1.24|MetaCyc:3.1.27.3-RXN		molecular_function											owl:Class	
GO:0043221	biolink:NamedThing	SMC family protein binding	Binding to a protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization.	got7fsn_ti	structural maintenance of chromosomes family protein binding													molecular_function											owl:Class	
GO:0039593	biolink:NamedThing	suppression by virus of host exit from mitosis	Any viral process which decreases the rate or extent of a host cell leaving M phase of the cell cycle. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	got7fsn_ti	inhibition of host mitotic exit by virus						bf	2012-06-25T02:21:20Z				VZ:877		biological_process											owl:Class	
GO:0018776	biolink:NamedThing	trans-chloroacrylic acid dehalogenase activity	Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde.	got7fsn_ti												UM-BBD_reactionID:r0689		molecular_function											owl:Class	
GO:0031431	biolink:NamedThing	Dbf4-dependent protein kinase complex	A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins.	got7fsn_ti	DDK|Hsk1-Dfp1 kinase complex|Cdc7-Dbf4 complex													cellular_component											owl:Class	
GO:0071883	biolink:NamedThing	MAPK-activating adrenergic receptor signaling pathway	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand and leading to the activation of a MAP kinase cascade.	got7fsn_ti	activation of MAP kinase activity by adrenergic receptor signalling pathway|activation of MAPK activity by adrenergic receptor signalling pathway|activation of MAPK activity by adrenergic receptor signaling pathway|activation of MAP kinase activity by adrenergic receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/21544					mah	2010-09-13T04:34:47Z						biological_process											owl:Class	
GO:0085019	biolink:NamedThing	formation of tubovesicular network for nutrient acquisition	The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	formation by symbiont of a tubovesicular network for nutrient acquisition from host|formation of a symbiont- induced tubovesicular network for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305					jl	2010-05-20T04:29:24Z						biological_process											owl:Class	
GO:0016894	biolink:NamedThing	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters.	got7fsn_ti	3'-endonuclease activity|endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters				Note that this activity can catalyze cleavage of DNA or RNA.							EC:3.1.31.-		molecular_function											owl:Class	
GO:0080031	biolink:NamedThing	methyl salicylate esterase activity	Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+.	got7fsn_ti	methylsalicylate esterase activity|methyl SA esterase activity|salicylic acid methyl ester esterase activity|MESA esterase activity											MetaCyc:RXNQT-4366		molecular_function											owl:Class	
GO:0047203	biolink:NamedThing	13-hydroxylupinine O-tigloyltransferase activity	Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA.	got7fsn_ti	tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase activity|(E)-2-methylcrotonoyl-CoA:13-hydroxylupinine O-2-methylcrotonoyltransferase activity|13-hydroxylupanine acyltransferase activity											MetaCyc:2.3.1.93-RXN|KEGG_REACTION:R04205|RHEA:12360|EC:2.3.1.93		molecular_function											owl:Class	
GO:0018448	biolink:NamedThing	hydroxymethylmethylsilanediol oxidase activity	Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.	got7fsn_ti												UM-BBD_reactionID:r0638		molecular_function											owl:Class	
GO:0045544	biolink:NamedThing	gibberellin 20-oxidase activity	Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones.	got7fsn_ti														molecular_function											owl:Class	
GO:0033079	biolink:NamedThing	immature T cell proliferation	The expansion of an immature T cell population by cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0007385	biolink:NamedThing	specification of segmental identity, abdomen	The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti														biological_process											owl:Class	
GO:0046738	biolink:NamedThing	induction of innate immune response in host by virus	The intentional, virally-encoded stimulation of an innate host defense response to viral infection.	got7fsn_ti	active induction of innate immune response in host by virus|active viral induction of innate immune response in host													biological_process											owl:Class	
GO:0044602	biolink:NamedThing	protein deadenylylation	The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid.	got7fsn_ti	protein deAMPylation						jl	2012-05-01T04:16:22Z						biological_process											owl:Class	
GO:0047239	biolink:NamedThing	hydroxymandelonitrile glucosyltransferase activity	Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H(+) + taxiphyllin + UDP.	got7fsn_ti	cyanohydrin glucosyltransferase activity|UDP-glucose:4-hydroxymandelonitrile glucosyltransferase activity|UDPglucose:4-hydroxymandelonitrile glucosyltransferase activity											EC:2.4.1.178|RHEA:15961|MetaCyc:2.4.1.178-RXN|KEGG_REACTION:R02709		molecular_function											owl:Class	
GO:0036152	biolink:NamedThing	phosphatidylethanolamine acyl-chain remodeling	Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.	got7fsn_ti							bf	2012-03-14T02:09:00Z						biological_process											owl:Class	
GO:0046470	biolink:NamedThing	phosphatidylcholine metabolic process	The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.	got7fsn_ti	phosphatidylcholine metabolism													biological_process											owl:Class	
GO:0007451	biolink:NamedThing	dorsal/ventral lineage restriction, imaginal disc	Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment.	got7fsn_ti	dorsal-ventral lineage restriction, imaginal disc|dorsoventral lineage restriction, imaginal disc													biological_process											owl:Class	
GO:0045464	biolink:NamedThing	R8 cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0003923	biolink:NamedThing	GPI-anchor transamidase activity	Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor.	got7fsn_ti												Reactome:R-HSA-162836		molecular_function											owl:Class	
GO:0098872	biolink:NamedThing	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse.	got7fsn_ti	G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration|G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels													molecular_function											owl:Class	
GO:0043719	biolink:NamedThing	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity	Catalysis of the reaction: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol + O2 + H+ = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + H2O.	got7fsn_ti												MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN|EC:1.14.13.-		molecular_function											owl:Class	
GO:0045459	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide	The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide.	got7fsn_ti	iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl triiron tetrasulphide											RESID:AA0326		biological_process											owl:Class	
GO:0038159	biolink:NamedThing	C-X-C chemokine receptor CXCR4 signaling pathway	A series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	CXCR4 signaling pathway						bf	2012-05-14T01:33:17Z						biological_process											owl:Class	
GO:0004370	biolink:NamedThing	glycerol kinase activity	Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+).	got7fsn_ti	glycerol kinase (phosphorylating)|ATP:glycerol 3-phosphotransferase activity|ATP:glycerol-3-phosphotransferase activity|GK|glyceric kinase activity|glycerokinase activity											MetaCyc:GLYCEROL-KIN-RXN|EC:2.7.1.30|KEGG_REACTION:R00847|RHEA:21644|Reactome:R-HSA-75887		molecular_function											owl:Class	
GO:0051002	biolink:NamedThing	ligase activity, forming nitrogen-metal bonds	Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	got7fsn_ti												EC:6.6.-.-		molecular_function											owl:Class	
GO:0010999	biolink:NamedThing	regulation of eIF2 alpha phosphorylation by heme	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.	got7fsn_ti							tb	2009-06-10T11:42:10Z						biological_process											owl:Class	
GO:0010770	biolink:NamedThing	positive regulation of cell morphogenesis involved in differentiation	Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	got7fsn_ti														biological_process											owl:Class	
GO:0042349	biolink:NamedThing	guiding stereospecific synthesis activity	The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis.	got7fsn_ti	dirigent protein													molecular_function											owl:Class	
GO:1990434	biolink:NamedThing	lower tip-link density	An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises.	got7fsn_ti	LTLD						sl	2014-07-30T16:34:34Z						cellular_component											owl:Class	
GO:0017166	biolink:NamedThing	vinculin binding	Binding to vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.	got7fsn_ti														molecular_function											owl:Class	
GO:0015941	biolink:NamedThing	pantothenate catabolic process	The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	got7fsn_ti	pantothenate catabolism|vitamin B5 catabolic process|pantothenate breakdown|pantothenate degradation|vitamin B5 catabolism													biological_process											owl:Class	
GO:0007144	biolink:NamedThing	female meiosis I	The cell cycle process in which the first meiotic division occurs in the female germline.	got7fsn_ti	female meiosis I nuclear division													biological_process											owl:Class	
GO:0071095	biolink:NamedThing	alpha3-beta1 integrin-thrombospondin complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin.	got7fsn_ti	ITGA3-ITGB1-THBS1 complex						mah	2009-11-06T04:48:03Z						cellular_component											owl:Class	
GO:0019086	biolink:NamedThing	late viral transcription	The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins.	got7fsn_ti	late viral mRNA transcription													biological_process											owl:Class	
GO:0099118	biolink:NamedThing	microtubule-based protein transport	A microtubule-based process that results in the transport of proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0004657	biolink:NamedThing	proline dehydrogenase activity	Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor.	got7fsn_ti	L-proline:(acceptor) oxidoreductase activity|L-proline dehydrogenase activity|L-proline:acceptor oxidoreductase activity											MetaCyc:RXN-7181|EC:1.5.99.8|Reactome:R-HSA-8955817|Reactome:R-HSA-6784224|Reactome:R-HSA-70670|RHEA:23784		molecular_function											owl:Class	
GO:0102304	biolink:NamedThing	sesquithujene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> 7-epi-sesquithujene + diphosphoric acid.	got7fsn_ti												EC:4.2.3.102|MetaCyc:RXN-12838|RHEA:31991		molecular_function											owl:Class	
GO:0031775	biolink:NamedThing	lutropin-choriogonadotropic hormone receptor binding	Binding to a lutropin-choriogonadotropic hormone receptor.	got7fsn_ti	lutropin-choriogonadotropic hormone receptor ligand													molecular_function											owl:Class	
GO:0102409	biolink:NamedThing	sn-2-glycerol-3-phosphate C16:0-CoA acyl transferase activity	Catalysis of the reaction: behenoyl-CoA + sn-glycerol 3-phosphate(2-) <=> coenzyme A + 2-docosanoyl-glycerol 3-phosphate.	got7fsn_ti												MetaCyc:RXN-13736		molecular_function											owl:Class	
GO:0019807	biolink:NamedThing	aspartoacylase activity	Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate.	got7fsn_ti	N-acyl-L-aspartate amidohydrolase activity|acylase II|N-acetylaspartate amidohydrolase activity|aminoacylase II activity|acetyl-aspartic deaminase activity											MetaCyc:ASPARTOACYLASE-RXN|Reactome:R-HSA-5691507|RHEA:10872|EC:3.5.1.15		molecular_function											owl:Class	
GO:0016966	biolink:NamedThing	nitric oxide reductase activity	Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide.	got7fsn_ti	CYP55|P450 nitric oxide reductase activity|nitrous-oxide:acceptor oxidoreductase (NO-forming)|nitrous-oxide:(acceptor) oxidoreductase (NO-forming)|cytochrome bc nitric oxide reductase activity|P450nor|nitrogen oxide reductase activity|nitric-oxide reductase activity										GO:0016967|GO:0016968	MetaCyc:NITRIC-OXIDE-REDUCTASE-RXN|KEGG_REACTION:R00294|EC:1.7.2.5|RHEA:30211		molecular_function											owl:Class	
GO:2000368	biolink:NamedThing	positive regulation of acrosomal vesicle exocytosis	Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.	got7fsn_ti	positive regulation of acrosomal granule exocytosis|positive regulation of acrosome exocytosis						yaf	2011-02-07T11:52:42Z						biological_process											owl:Class	
GO:0005171	biolink:NamedThing	hepatocyte growth factor receptor binding	Binding to an hepatocyte growth factor receptor.	got7fsn_ti	HGF receptor binding|hepatocyte growth factor|hepatocyte growth factor receptor ligand													molecular_function											owl:Class	
GO:0090618	biolink:NamedThing	DNA clamp unloading	The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates.	got7fsn_ti	PCNA unloading						tb	2014-10-29T12:57:05Z						biological_process											owl:Class	
GO:0002000	biolink:NamedThing	detection of renal blood flow	The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0090580	biolink:NamedThing	phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand.	got7fsn_ti							tb	2014-05-14T15:52:41Z						molecular_function											owl:Class	
GO:0005883	biolink:NamedThing	neurofilament	A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.	got7fsn_ti	type IV intermediate filament											Wikipedia:Neurofilament|NIF_Subcellular:sao1316272517		cellular_component											owl:Class	
GO:1990518	biolink:NamedThing	single-stranded 3'-5' DNA helicase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'.	got7fsn_ti							al	2014-10-22T10:17:40Z						molecular_function											owl:Class	
GO:1900819	biolink:NamedThing	orlandin metabolic process	The chemical reactions and pathways involving orlandin.	got7fsn_ti	orlandin metabolism						di	2012-06-04T10:14:55Z						biological_process											owl:Class	
GO:0102607	biolink:NamedThing	3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity	Catalysis of the reaction: 3beta-hydroxy-12,15-cassadiene-11-one + NADPH + O2 + H+ <=> 2beta,3beta-dihydroxy-12,15-cassadiene-11-one + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15433		molecular_function											owl:Class	
GO:0000713	biolink:NamedThing	meiotic heteroduplex formation	During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0001856	biolink:NamedThing	complement component C5a binding	Binding to a C5a product of the complement cascade.	got7fsn_ti														molecular_function											owl:Class	
GO:0006124	biolink:NamedThing	ferredoxin metabolic process	The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.	got7fsn_ti	ferredoxin metabolism													biological_process											owl:Class	
GO:0014702	biolink:NamedThing	free sarcoplasmic reticulum membrane	The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0047481	biolink:NamedThing	D-alanine-alanyl-poly(glycerolphosphate) ligase activity	Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP.	got7fsn_ti	D-alanine:membrane-acceptor ligase activity|D-alanyl-poly(phosphoglycerol) synthetase activity|D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming)|D-alanyl-alanyl-poly(glycerolphosphate) synthetase activity|D-alanylalanylpoly(phosphoglycerol) synthetase activity|D-alanine-membrane acceptor-ligase activity											MetaCyc:6.3.2.16-RXN|EC:6.3.2.16		molecular_function											owl:Class	
GO:0035582	biolink:NamedThing	sequestering of BMP in extracellular matrix	Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.	got7fsn_ti	BMP sequestration in the ECM|negative regulation of BMP signalling pathway by extracellular matrix sequestering of BMP|negative regulation of BMP signaling pathway by extracellular sequestering of BMP|negative regulation of bone morphogenetic protein signaling pathway by extracellular matrix sequestering of bone morphogenetic protein				Confining BMP in the extracellular matrix may be achieved by binding BMP directly, or by binding to members of a BMP-containing complex.		bf	2010-10-12T03:12:45Z						biological_process											owl:Class	
GO:0102825	biolink:NamedThing	quercetin 3-O-rhamnoside-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + quercetin 3-O-rhamnoside <=> quercetin 3-O-rhamnoside-7-O-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-8268		molecular_function											owl:Class	
GO:0106323	biolink:NamedThing	(S)-limonene 1,2-monooxygenase NADPH activity	Catalysis of the reaction: (4S)-limonene + NADPH+= + H+ + O2 = NADP+ + H2O + (4S)-limonene-1,2-epoxide.	got7fsn_ti							hjd	2020-09-23T15:35:43Z				RHEA:26085		molecular_function											owl:Class	
GO:0035754	biolink:NamedThing	B cell chemotaxis	The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti							bf	2011-03-23T10:30:33Z						biological_process											owl:Class	
GO:0036366	biolink:NamedThing	transforming growth factor beta3 activation	The release of transforming growth factor beta 3 (TGF-beta3) from its latent state.	got7fsn_ti	TGF-beta 3 activation|TGFB3 activation|TGFbeta 3 activation						bf	2012-09-24T10:16:05Z						biological_process											owl:Class	
GO:0031479	biolink:NamedThing	myosin IX complex	A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:1990935	biolink:NamedThing	splicing factor binding	Binding to a protein involved in the process of removing sections of the primary RNA transcript to form the mature form of the RNA.	got7fsn_ti							sl	2016-03-21T21:57:20Z						molecular_function											owl:Class	
GO:0061732	biolink:NamedThing	mitochondrial acetyl-CoA biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA.	got7fsn_ti							dph	2015-08-24T13:44:02Z				Reactome:R-HSA-372342.1|Reactome:R-HSA-71397.1		biological_process											owl:Class	
GO:0007121	biolink:NamedThing	bipolar cellular bud site selection	The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.	got7fsn_ti	polar budding|bipolar budding|bipolar bud site selection													biological_process											owl:Class	
GO:0062240	biolink:NamedThing	euchromatin-nuclear membrane anchor activity	Binding to euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization.	got7fsn_ti	euchromatin-nuclear membrane tether activity|nuclear membrane-euchromatin anchor activity|nuclear membrane-euchromatin tether activity						dph	2020-04-20T18:22:35Z						molecular_function											owl:Class	
GO:0047122	biolink:NamedThing	quinaldate 4-oxidoreductase activity	Catalysis of the reaction: A + H(2)O + quinaldate = AH(2) + kynurenate.	got7fsn_ti	quinaldic acid 4-oxidoreductase activity|quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating)											KEGG_REACTION:R03687|MetaCyc:1.3.99.18-RXN|EC:1.3.99.18|RHEA:16697		molecular_function											owl:Class	
GO:0071919	biolink:NamedThing	G-quadruplex DNA formation	A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature.	got7fsn_ti	G quartet DNA formation|G-quartet DNA formation|G quadruplex DNA formation						mah	2010-09-24T10:57:43Z						biological_process											owl:Class	
GO:0102772	biolink:NamedThing	sphingolipid long-chain base 4-hydroxylase activity	Catalysis of the reaction: O2 + H+ + a dihydroceramide + NAD(P)H = H2O + a phytoceramide + NAD(P).	got7fsn_ti												MetaCyc:RXN-7797		molecular_function											owl:Class	
GO:0015018	biolink:NamedThing	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity	Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.	got7fsn_ti	UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity|uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity|glucuronosyltransferase I activity|UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity											RHEA:24168|EC:2.4.1.135|Reactome:R-HSA-9638064|Reactome:R-HSA-1889955|Reactome:R-HSA-3560802|MetaCyc:2.4.1.135-RXN		molecular_function											owl:Class	
GO:0002551	biolink:NamedThing	mast cell chemotaxis	The movement of a mast cell in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0050967	biolink:NamedThing	detection of electrical stimulus involved in sensory perception of pain	The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.	got7fsn_ti	detection of electrical stimulus during sensory perception of pain|perception of pain, detection of electrical stimulus|sensory transduction of electrical stimulus during perception of pain|perception of pain, sensory detection of electrical stimulus|sensory detection of electrical stimulus during perception of pain|perception of pain, sensory transduction of electrical stimulus													biological_process											owl:Class	
GO:0055002	biolink:NamedThing	striated muscle cell development	The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.	got7fsn_ti														biological_process											owl:Class	
GO:0008623	biolink:NamedThing	CHRAC	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair.	got7fsn_ti	chromatin accessibility complex|ISW2 complex										GO:0016588			cellular_component											owl:Class	
GO:0061751	biolink:NamedThing	neutral sphingomyelin phosphodiesterase activity	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment.	got7fsn_ti	neutral SMase|neutral sphingomyelinase						dph	2015-11-11T14:48:08Z						molecular_function											owl:Class	
GO:0002087	biolink:NamedThing	regulation of respiratory gaseous exchange by nervous system process	A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.	got7fsn_ti	neurological control of breathing|regulation of respiratory gaseous exchange by neurological system process													biological_process											owl:Class	
GO:0106226	biolink:NamedThing	peptide 2-hydroxyisobutyryltransferase activity	Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide.	got7fsn_ti							hjd	2019-10-17T18:55:24Z				RHEA:24180		molecular_function											owl:Class	
GO:0004397	biolink:NamedThing	histidine ammonia-lyase activity	Catalysis of the reaction: L-histidine = urocanate + NH3.	got7fsn_ti	L-histidine ammonia-lyase (urocanate-forming)|histidase activity|histidinase activity|histidine alpha-deaminase activity|L-histidine ammonia-lyase activity											EC:4.3.1.3|MetaCyc:HISTIDINE-AMMONIA-LYASE-RXN|RHEA:21232|Reactome:R-HSA-70899		molecular_function											owl:Class	
GO:0075218	biolink:NamedThing	zoospore encystment on host	The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0071322	biolink:NamedThing	cellular response to carbohydrate stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.	got7fsn_ti							mah	2009-12-10T05:13:33Z						biological_process											owl:Class	
GO:0102091	biolink:NamedThing	phosphatidylinositol-5-phosphate 5-phosphatase activity	Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = hydrogenphosphate + an L-1-phosphatidyl-inositol.	got7fsn_ti												MetaCyc:RXN-10962		molecular_function											owl:Class	
GO:0016015	biolink:NamedThing	morphogen activity	Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.	got7fsn_ti														molecular_function											owl:Class	
GO:0007198	biolink:NamedThing	adenylate cyclase-inhibiting serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	got7fsn_ti	serotonin receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by serotonin receptor signaling pathway|serotonin receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by serotonin receptor signalling pathway													biological_process											owl:Class	
GO:0036291	biolink:NamedThing	protein cis-autophosphorylation	The phosphorylation by a protein of one or more of its own amino acid residues.	got7fsn_ti	cis-autophosphorylation						bf	2012-07-18T10:27:06Z						biological_process											owl:Class	
GO:0060640	biolink:NamedThing	positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling	Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.	got7fsn_ti	positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signaling|positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signalling						dph	2009-05-20T04:33:52Z						biological_process											owl:Class	
GO:0042488	biolink:NamedThing	positive regulation of odontogenesis of dentin-containing tooth	Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.	got7fsn_ti	upregulation of odontogenesis|activation of odontogenesis|positive regulation of odontogenesis of dentine-containing teeth|positive regulation of odontogenesis of dentine-containing tooth|up regulation of odontogenesis|stimulation of odontogenesis|up-regulation of odontogenesis													biological_process											owl:Class	
GO:0010128	biolink:NamedThing	benzoate catabolic process via CoA ligation	The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway.	got7fsn_ti	anaerobic benzoate degradation|anaerobic benzoate breakdown|anaerobic benzoate catabolic process|anaerobic benzoate catabolism											MetaCyc:PWY-283		biological_process											owl:Class	
GO:0070994	biolink:NamedThing	detection of oxidative stress	The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal.	got7fsn_ti							mah	2009-10-30T02:54:35Z						biological_process											owl:Class	
GO:1990002	biolink:NamedThing	methylglyoxal reductase (NADPH-dependent, acetol producing)	Catalysis of the reaction: H+ + methylglyoxal + NADPH <=> hydroxyacetone + NADP+.	got7fsn_ti							jl	2012-12-05T15:55:06Z				RHEA:27986		molecular_function											owl:Class	
GO:1990053	biolink:NamedThing	DNA-5-methylcytosine glycosylase activity	Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site.	got7fsn_ti							tb	2013-02-22T01:09:06Z						molecular_function											owl:Class	
GO:0019768	biolink:NamedThing	high-affinity IgE receptor activity	Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	high affinity IgE receptor activity|high affinity Fc receptor activity													molecular_function											owl:Class	
GO:0051734	biolink:NamedThing	polynucleotide kinase activity	Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.	got7fsn_ti	ATP-dependent polynucleotide kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP:5'-dephosphopolynucleotide 5'-phosphotransferase activity|ATP:5'-dephosphopolynucleotide 5'-phosphatase activity	https://github.com/geneontology/go-ontology/issues/21619										EC:2.7.1.78|RHEA:54580		molecular_function											owl:Class	
GO:0016131	biolink:NamedThing	brassinosteroid metabolic process	The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.	got7fsn_ti	brassinosteroid metabolism													biological_process											owl:Class	
GO:0102328	biolink:NamedThing	3-oxoacid decarboxylase activity	Catalysis of the reaction: H+ + a 3-oxoacid = carbon dioxide + a methylketone.	got7fsn_ti												MetaCyc:RXN-13248		molecular_function											owl:Class	
GO:0047825	biolink:NamedThing	D-lactate-2-sulfatase activity	Catalysis of the reaction: (R)-2-O-sulfolactate + H(2)O = (R)-lactate + H(+) + sulfate.	got7fsn_ti	(S)-2-O-sulfolactate 2-sulfohydrolase activity|D-lactate-2-sulphatase activity											KEGG_REACTION:R01448|RHEA:20337|MetaCyc:D-LACTATE-2-SULFATASE-RXN|EC:3.1.6.17		molecular_function											owl:Class	
GO:0102586	biolink:NamedThing	cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity	Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6'-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-15332		molecular_function											owl:Class	
GO:0004344	biolink:NamedThing	glucose dehydrogenase activity	Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor.	got7fsn_ti	D-glucose:acceptor 1-oxidoreductase|glucose dehydrogenase (Aspergillus) activity|glucose dehydrogenase (acceptor) activity|glucose dehydrogenase (decarboxylating)|D-glucose:(acceptor) 1-oxidoreductase										GO:0008708	RHEA:24540|MetaCyc:GLUCOSE-DEHYDROGENASE-ACCEPTOR-RXN|EC:1.1.99.10|KEGG_REACTION:R00305		molecular_function											owl:Class	
GO:0047608	biolink:NamedThing	acetylindoxyl oxidase activity	Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown.	got7fsn_ti	N-acetylindoxyl:oxygen oxidoreductase activity											MetaCyc:ACETYLINDOXYL-OXIDASE-RXN|RHEA:16941|EC:1.7.3.2		molecular_function											owl:Class	
GO:0016977	biolink:NamedThing	chitosanase activity	Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.	got7fsn_ti	chitosan N-acetylglucosaminohydrolase activity											MetaCyc:3.2.1.132-RXN|EC:3.2.1.132		molecular_function											owl:Class	
GO:0044715	biolink:NamedThing	8-oxo-dGDP phosphatase activity	Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.	got7fsn_ti							jl	2012-10-18T13:31:09Z				RHEA:32063|Reactome:R-HSA-2395879|EC:3.6.1.58|Reactome:R-HSA-2395873		molecular_function											owl:Class	
GO:0031694	biolink:NamedThing	alpha-2A adrenergic receptor binding	Binding to an alpha-2A adrenergic receptor.	got7fsn_ti	alpha-2A adrenergic receptor ligand													molecular_function											owl:Class	
GO:0010934	biolink:NamedThing	macrophage cytokine production	The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0016339	biolink:NamedThing	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.	got7fsn_ti	calcium-dependent cell adhesion molecule activity													biological_process											owl:Class	
GO:1990600	biolink:NamedThing	single-stranded DNA endodeoxyribonuclease activator activity	Increases the activity of a single-stranded DNA endodeoxyribonuclease activator activity.	got7fsn_ti							al	2015-01-06T15:35:36Z						molecular_function											owl:Class	
GO:0033882	biolink:NamedThing	choloyl-CoA hydrolase activity	Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA.	got7fsn_ti	choloyl-coenzyme A thioesterase activity|PTE-2|peroxisomal acyl-CoA thioesterase 2 activity|chenodeoxycholoyl-coenzyme A thioesterase activity											EC:3.1.2.27|RHEA:14541|MetaCyc:3.1.2.27-RXN		molecular_function											owl:Class	
GO:0016973	biolink:NamedThing	poly(A)+ mRNA export from nucleus	The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.	got7fsn_ti	polyadenylated mRNA export from nucleus|poly(A)+ mRNA transport from nucleus to cytoplasm|poly(A)+ mRNA export out of nucleus|poly(A)+ mRNA export from cell nucleus|poly(A)+ mRNA-nucleus export|poly(A) mRNA export from nucleus													biological_process											owl:Class	
GO:0032942	biolink:NamedThing	inositol tetrakisphosphate 2-kinase activity	Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP.	got7fsn_ti	inositol-tetrakisphosphate 2-kinase activity|inositol 1,3,4,6-tetrakisphosphate 2-kinase activity|1D-myo-inositol-tetrakisphosphate 2-kinase activity											EC:2.7.1.-		molecular_function											owl:Class	
GO:0036067	biolink:NamedThing	light-dependent chlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light.	got7fsn_ti	light-dependent chlorophyll biosynthesis|light-dependent chlorophyll formation|light-dependent chlorophyll anabolism|light dependent chlorophyll biosynthetic process|light-dependent chlorophyll synthesis						bf	2011-12-15T04:42:47Z						biological_process											owl:Class	
GO:0044210	biolink:NamedThing	'de novo' CTP biosynthetic process	The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.	got7fsn_ti	'de novo' cytidine 5'-triphosphate biosynthetic process						jl	2009-10-22T03:22:34Z						biological_process											owl:Class	
GO:0006241	biolink:NamedThing	CTP biosynthetic process	The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate.	got7fsn_ti	CTP formation|CTP anabolism|CTP biosynthesis|CTP synthesis													biological_process											owl:Class	
GO:0002479	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.	got7fsn_ti	cross-presentation|exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent|cross presentation|TAP-dependent exogenous peptide antigen processing and presentation via MHC class I|TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I													biological_process											owl:Class	
GO:0004588	biolink:NamedThing	orotate phosphoribosyltransferase activity	Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.	got7fsn_ti	OPRTase activity|orotidine 5'-monophosphate pyrophosphorylase activity|orotidylate pyrophosphorylase activity|orotidylic pyrophosphorylase activity|OPRT activity|orotic acid phosphoribosyltransferase activity|orotidylic acid pyrophosphorylase activity|orotidylic phosphorylase activity|orotidylic acid phosphorylase activity|orotidine monophosphate pyrophosphorylase activity|orotidine-5'-phosphate pyrophosphorylase activity|orotidine-5'-phosphate diphosphorylase activity|orotidine phosphoribosyltransferase activity|orotidylate phosphoribosyltransferase activity|orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity|orotate phosphoribosyl pyrophosphate transferase activity											MetaCyc:OROPRIBTRANS-RXN|RHEA:10380|Reactome:R-HSA-73567|EC:2.4.2.10		molecular_function											owl:Class	
GO:0036344	biolink:NamedThing	platelet morphogenesis	Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.	got7fsn_ti							bf	2012-09-11T15:15:35Z						biological_process											owl:Class	
GO:0050515	biolink:NamedThing	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity	Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+).	got7fsn_ti	CDP-ME kinase activity|ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase activity|4-diphosphocytidyl-2C-methyl-D-erythritol kinase activity|4-diphosphocytidyl-2-C-methyl-D-erythritol kinase activity|CMK activity										GO:0008698	KEGG_REACTION:R05634|EC:2.7.1.148|MetaCyc:2.7.1.148-RXN|RHEA:18437		molecular_function											owl:Class	
GO:0046595	biolink:NamedThing	establishment of pole plasm mRNA localization	Any process that results in the directed movement of mRNA to the oocyte pole plasm.	got7fsn_ti	establishment of oocyte pole plasm mRNA localization|establishment of pole plasm mRNA localisation										GO:0048121			biological_process											owl:Class	
GO:0047626	biolink:NamedThing	adenosylmethionine hydrolase activity	Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O = S-methyl-5'-thioadenosine + L-homoserine + H(+).	got7fsn_ti	adenosylmethionine lyase activity|methylmethionine-sulfonium-salt hydrolase activity|S-adenosyl-L-methionine hydrolase activity|S-adenosylmethionine cleaving enzyme activity|adenosyl methionine hydrolase activity											MetaCyc:ADENOSYLMETHIONINE-HYDROLASE-RXN|KEGG_REACTION:R00175|EC:3.3.1.2|RHEA:14645		molecular_function											owl:Class	
GO:0099400	biolink:NamedThing	caveola neck	A membrane microdomain that forms a necklace around the bulb (crater) of a caveola.  Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it.	got7fsn_ti														cellular_component											owl:Class	
GO:0019464	biolink:NamedThing	glycine decarboxylation via glycine cleavage system	The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.	got7fsn_ti	glycine cleavage system											MetaCyc:GLYCLEAV-PWY		biological_process											owl:Class	
GO:0006546	biolink:NamedThing	glycine catabolic process	The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid.	got7fsn_ti	glycine breakdown|glycine catabolism|glycine degradation													biological_process											owl:Class	
GO:0102123	biolink:NamedThing	gibberellin A4 16alpha,17 epoxidase activity	Catalysis of the reaction: gibberellin A4 + O2 + H+ + NAD(P)H <=> 16alpha,17-epoxy gibberellin A4 + H2O + NAD(P).	got7fsn_ti												MetaCyc:RXN-11385		molecular_function											owl:Class	
GO:0004461	biolink:NamedThing	lactose synthase activity	Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose.	got7fsn_ti	uridine diphosphogalactose-glucose galactosyltransferase activity|UDPgalactose:D-glucose 4-beta-D-galactotransferase activity|lactose synthetase activity|UDP-galactose:D-glucose 4-beta-D-galactotransferase activity|UDPgalactose-glucose galactosyltransferase activity|UDP-galactose-glucose galactosyltransferase activity											RHEA:12404|EC:2.4.1.22|MetaCyc:LACTOSE-SYNTHASE-RXN|Reactome:R-HSA-5653878		molecular_function											owl:Class	
GO:0035046	biolink:NamedThing	pronuclear migration	The directed movement of the male and female pronuclei towards each other prior to their fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0052712	biolink:NamedThing	inositol phosphosphingolipid phospholipase activity	Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol.	got7fsn_ti							ai	2011-08-05T04:49:13Z						molecular_function											owl:Class	
GO:0005668	biolink:NamedThing	RNA polymerase transcription factor SL1 complex	A RNA polymerase I-specific transcription factor complex that contains the TATA-box-binding protein (TBP) and at least three TBP-associated factors including proteins known in mammals as TAFI110, TAFI63 and TAFI48.	got7fsn_ti	selectivity factor SL1 complex|TIF-IB													cellular_component											owl:Class	
GO:0102955	biolink:NamedThing	S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity	Catalysis of the reaction: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine  = menaquinol-7 + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												EC:2.1.1.163|RHEA:33255|MetaCyc:RXN-9191		molecular_function											owl:Class	
GO:0102358	biolink:NamedThing	daphnetin-8-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 7,8-dihydroxycoumarin <=> S-adenosyl-L-homocysteine  + 7-hydroxy-8-methoxycoumarin + H+.	got7fsn_ti												MetaCyc:RXN-13448		molecular_function											owl:Class	
GO:0106146	biolink:NamedThing	sideretin biosynthesis	The chemical reactions and pathways resulting in the formation of sideretin.	got7fsn_ti							hjd	2018-09-07T18:31:30Z						biological_process											owl:Class	
GO:0032442	biolink:NamedThing	phenylcoumaran benzylic ether reductase activity	Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.	got7fsn_ti	PCBER activity													molecular_function											owl:Class	
GO:0060002	biolink:NamedThing	plus-end directed microfilament motor activity	A motor activity that generates movement along a microfilament towards the plus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.	got7fsn_ti	plus-end directed actin-filament motor activity|barbed-end directed actin-filament motor activity|plus-end directed actin filament motor activity													molecular_function											owl:Class	
GO:0043700	biolink:NamedThing	pterinosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.	got7fsn_ti														cellular_component											owl:Class	
GO:0047060	biolink:NamedThing	(R)-pantolactone dehydrogenase (flavin) activity	Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2).	got7fsn_ti	(R)-pantolactone:acceptor oxidoreductase (flavin-containing)|2-dehydropantoyl-lactone reductase (flavin) activity|(R)-pantoyllactone dehydrogenase (flavin) activity|2-dehydropantolactone reductase (flavin) activity											KEGG_REACTION:R03156|EC:1.1.99.27|RHEA:21004|MetaCyc:1.1.99.27-RXN		molecular_function											owl:Class	
GO:0050152	biolink:NamedThing	omega-amidase activity	Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3.	got7fsn_ti	w-amidase activity|alpha-keto acid-omega-amidase activity|omega-amidodicarboxylate amidohydrolase activity											MetaCyc:OMEGA-AMIDASE-RXN|RHEA:11716|EC:3.5.1.3		molecular_function											owl:Class	
GO:0017118	biolink:NamedThing	lipoyltransferase activity	Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme.	got7fsn_ti												RHEA:20473		molecular_function											owl:Class	
GO:0034347	biolink:NamedThing	type III interferon binding	Binding to a type III interferon. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	interferon-lambda binding				Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.									molecular_function											owl:Class	
GO:0072499	biolink:NamedThing	photoreceptor cell axon guidance	The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.	got7fsn_ti	photoreceptor cell axon pathfinding						mah	2010-12-15T05:34:10Z						biological_process											owl:Class	
GO:0061258	biolink:NamedThing	mesonephric glomerular visceral epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.	got7fsn_ti							dph	2010-08-30T02:13:33Z						biological_process											owl:Class	
GO:0060814	biolink:NamedThing	posterior mRNA localization involved in anterior/posterior axis specification	Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.	got7fsn_ti	posterior mRNA localisation involved in anterior/posterior axis specification						dph	2009-08-07T09:54:54Z						biological_process											owl:Class	
GO:0010471	biolink:NamedThing	GDP-galactose:mannose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: GDP-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + alpha-L-galactose-1-phosphate.	got7fsn_ti	GDP-L-galactose phosphorylase activity|GDP-L-galactose:mannose-1-phosphate guanylyltransferase activity											MetaCyc:RXN4FS-12		molecular_function											owl:Class	
GO:0047494	biolink:NamedThing	serine-phosphoethanolamine synthase activity	Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H(+).	got7fsn_ti	serine-phosphinico-ethanolamine synthase activity|serine ethanolaminephosphotransferase activity|CDP-ethanolamine:L-serine ethanolamine phosphotransferase activity|serine ethanolamine phosphodiester synthase activity|serine ethanolamine phosphate synthetase activity|serinephosphoethanolamine synthase activity											KEGG_REACTION:R02563|MetaCyc:SERINE-PHOSPHOETHANOLAMINE-SYNTHASE-RXN|EC:2.7.8.4|RHEA:22656		molecular_function											owl:Class	
GO:0009996	biolink:NamedThing	negative regulation of cell fate specification	Any process that restricts, stops or prevents a cell from adopting a specific cell fate.	got7fsn_ti	down-regulation of cell fate specification|downregulation of cell fate specification|down regulation of cell fate specification|inhibition of cell fate specification|suppression of cell fate													biological_process											owl:Class	
GO:0009551	biolink:NamedThing	secondary plasmodesma	A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata.	got7fsn_ti														cellular_component											owl:Class	
GO:0072665	biolink:NamedThing	protein localization to vacuole	A process in which a protein is transported to, or maintained at, a location in a vacuole.	got7fsn_ti	protein localisation to vacuole						mah	2011-02-14T02:55:35Z						biological_process											owl:Class	
GO:0043338	biolink:NamedThing	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity	Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol.	got7fsn_ti	CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase											RHEA:25690|EC:2.7.7.67		molecular_function											owl:Class	
GO:0034676	biolink:NamedThing	integrin alpha6-beta4 complex	An integrin complex that comprises one alpha6 subunit and one beta4 subunit.	got7fsn_ti	alpha6-beta4 integrin complex|ITGA6-ITGB4 complex													cellular_component											owl:Class	
GO:0006856	biolink:NamedThing	eye pigment precursor transport	The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0047236	biolink:NamedThing	methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity	Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP.	got7fsn_ti	methyl-ONN-azoxymethanol glucosyltransferase activity|UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity|UDPglucose-methylazoxymethanol glucosyltransferase activity|cycasin synthase activity|uridine diphosphoglucose-methylazoxymethanol glucosyltransferase activity											RHEA:20205|MetaCyc:2.4.1.171-RXN|EC:2.4.1.171		molecular_function											owl:Class	
GO:0102945	biolink:NamedThing	soyasapogenol B UDP-glucosyl transferase activity	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + soyasapogenol B <=> UDP(3-) + a soyasapogenol B monoglucoside.	got7fsn_ti												MetaCyc:RXN-9037		molecular_function											owl:Class	
GO:0102141	biolink:NamedThing	[chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate.	got7fsn_ti												MetaCyc:RXN-11560		molecular_function											owl:Class	
GO:0002316	biolink:NamedThing	follicular B cell differentiation	The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.	got7fsn_ti	follicular B-cell differentiation|follicular B cell development|follicular B lymphocyte differentiation|follicular B-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0047196	biolink:NamedThing	long-chain-alcohol O-fatty-acyltransferase activity	Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA.	got7fsn_ti	wax-ester synthase activity|wax ester synthase activity|wax synthase activity|acyl-CoA:long-chain-alcohol O-acyltransferase activity										GO:0103095	Reactome:R-HSA-5696424|MetaCyc:RXNQT-4193|Reactome:R-HSA-8848582|MetaCyc:2.3.1.75-RXN|RHEA:38443|EC:2.3.1.75		molecular_function											owl:Class	
GO:0033936	biolink:NamedThing	polymannuronate hydrolase activity	Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate.	got7fsn_ti	poly(mannuronide) mannuronohydrolase activity|polymannuronic acid polymerase activity											MetaCyc:3.2.1.121-RXN|EC:3.2.1.121		molecular_function											owl:Class	
GO:0090269	biolink:NamedThing	fibroblast growth factor production	The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti							tb	2010-02-05T02:33:33Z						biological_process											owl:Class	
GO:0003866	biolink:NamedThing	3-phosphoshikimate 1-carboxyvinyltransferase activity	Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.	got7fsn_ti	5-enolpyruvylshikimate-3-phosphate synthase activity|3-enol-pyruvoylshikimate-5-phosphate synthase activity|phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase activity|EPSP synthase activity											KEGG_REACTION:R03460|EC:2.5.1.19|RHEA:21256|MetaCyc:2.5.1.19-RXN		molecular_function											owl:Class	
GO:0102522	biolink:NamedThing	tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 4-demethylwyosine37 in tRNAPhe <=> 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe.	got7fsn_ti												MetaCyc:RXN-14518|RHEA:36355|EC:2.5.1.114		molecular_function											owl:Class	
GO:0018543	biolink:NamedThing	4-amino-2-nitroso-6-nitrotoluene reductase activity	Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene.	got7fsn_ti												UM-BBD_reactionID:r0464		molecular_function											owl:Class	
GO:0072703	biolink:NamedThing	cellular response to methyl methanesulfonate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.	got7fsn_ti	cellular response to MMS						mah	2012-04-11T03:04:18Z						biological_process											owl:Class	
GO:0008071	biolink:NamedThing	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded	Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	maternal determination of dorsal-ventral axis, ovarian follicular epithelium, soma encoded|maternal determination of dorsoventral axis, ovarian follicular epithelium, soma encoded|maternal determination of dorsal/ventral axis, follicular epithelium, soma encoded													biological_process											owl:Class	
GO:0030254	biolink:NamedThing	protein secretion by the type III secretion system	The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.	got7fsn_ti	type III protein secretion system|protein secretion by the T3SS|protein secretion by the T3S|protein secretion by the type III protein secretion system|protein secretion by the TTSS				Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type III protein secretion system complex ; GO:0030257'. Note that this term is used for annotation of proteins that compose the secretion complex but not the proteins being secreted.									biological_process											owl:Class	
GO:0010406	biolink:NamedThing	classical arabinogalactan protein metabolic process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored.	got7fsn_ti	classical-arabinogalactan protein metabolism													biological_process											owl:Class	
GO:0021906	biolink:NamedThing	hindbrain-spinal cord boundary formation	The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.	got7fsn_ti														biological_process											owl:Class	
GO:0021666	biolink:NamedThing	rhombomere 5 formation	The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0004687	biolink:NamedThing	myosin light chain kinase activity	Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.	got7fsn_ti	ATP:myosin-light-chain O-phosphotransferase|smooth-muscle-myosin-light-chain kinase activity|calcium/calmodulin-dependent myosin light chain kinase activity|ATP:myosin-light-chain O-phosphotransferase activity|myosin light chain protein kinase activity|myosin light-chain kinase (phosphorylating)|MLCK|myosin light-chain kinase|myosin kinase activity|MLCkase activity|myosin light-chain kinase activity|myosin-light-chain kinase activity|myosin light-chain kinase (phosphorylating) activity|STK18											EC:2.7.11.18|Reactome:R-HSA-445813|Reactome:R-HSA-5668978|RHEA:22004|MetaCyc:2.7.11.18-RXN		molecular_function											owl:Class	
GO:0050838	biolink:NamedThing	peptidyl-5-hydroxy-L-lysine trimethylation	The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.	got7fsn_ti												RESID:AA0359		biological_process											owl:Class	
GO:0106009	biolink:NamedThing	(4S)-4-hydroxy-2-oxoglutarate aldolase activity	Catalysis of the reaction:(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.	got7fsn_ti							hjd	2017-04-25T14:14:58Z				RHEA:35639|EC:4.1.3.42		molecular_function											owl:Class	
GO:0047858	biolink:NamedThing	dihydroxyfumarate decarboxylase activity	Catalysis of the reaction: dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2).	got7fsn_ti	dihydroxyfumarate carboxy-lyase activity|dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming)											RHEA:13845|KEGG_REACTION:R03127|EC:4.1.1.54|MetaCyc:DIHYDROXYFUMARATE-DECARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0036405	biolink:NamedThing	anchored component of cell outer membrane	The component of the cell outer membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti	anchored to cell outer membrane						bf	2013-08-15T11:40:41Z						cellular_component											owl:Class	
GO:0072187	biolink:NamedThing	metanephric cap formation	The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.	got7fsn_ti							mah	2010-03-01T01:26:53Z						biological_process											owl:Class	
GO:0050044	biolink:NamedThing	galactose-6-phosphate isomerase activity	Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate.	got7fsn_ti	D-galactose-6-phosphate ketol-isomerase activity|D-galactose-6-phosphate aldose-ketose-isomerase activity											EC:5.3.1.26|RHEA:13033|MetaCyc:LACTOSE-6-PHOSPHATE-ISOMERASE-RXN|KEGG_REACTION:R03240		molecular_function											owl:Class	
GO:0071257	biolink:NamedThing	cellular response to electrical stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.	got7fsn_ti	cellular response to electricity						mah	2009-12-04T03:27:03Z						biological_process											owl:Class	
GO:0047468	biolink:NamedThing	phosphoglucomutase (glucose-cofactor) activity	Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor.	got7fsn_ti	alpha-D-glucose 1,6-phosphomutase (glucose-cofactor)|glucose-1-phosphate phosphotransferase activity											MetaCyc:5.4.2.5-RXN|EC:5.4.2.5		molecular_function											owl:Class	
GO:0004614	biolink:NamedThing	phosphoglucomutase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.	got7fsn_ti	glucose phosphomutase activity|phosphoglucose mutase activity|alpha-D-glucose 1,6-phosphomutase activity											Reactome:R-HSA-9638125|Reactome:R-HSA-9638127|Reactome:R-HSA-5609939|Reactome:R-HSA-70272|MetaCyc:PHOSPHOGLUCMUT-RXN|Reactome:R-HSA-70427|RHEA:23536|EC:5.4.2.2		molecular_function											owl:Class	
GO:0060577	biolink:NamedThing	pulmonary vein morphogenesis	The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.	got7fsn_ti	pulmonary venous blood vessel morphogenesis						dph	2009-05-06T08:44:04Z						biological_process											owl:Class	
GO:0035156	biolink:NamedThing	fusion cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0010187	biolink:NamedThing	negative regulation of seed germination	Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination.	got7fsn_ti	inhibition of seed germination|down-regulation of seed germination|down regulation of seed germination|downregulation of seed germination													biological_process											owl:Class	
GO:0030971	biolink:NamedThing	receptor tyrosine kinase binding	Binding to a receptor that possesses protein tyrosine kinase activity.	got7fsn_ti	transmembrane receptor protein tyrosine kinase ligand binding													molecular_function											owl:Class	
GO:1990782	biolink:NamedThing	protein tyrosine kinase binding	Binding to protein tyrosine kinase.	got7fsn_ti	tyrosine kinase binding						sl	2015-06-23T20:50:58Z						molecular_function											owl:Class	
GO:0030739	biolink:NamedThing	O-demethylpuromycin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin.	got7fsn_ti	O-demethylpuromycin methyltransferase activity|S-adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase activity											RHEA:22280|EC:2.1.1.38|MetaCyc:2.1.1.38-RXN		molecular_function											owl:Class	
GO:0047640	biolink:NamedThing	aldose 1-dehydrogenase activity	Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH.	got7fsn_ti	aldose dehydrogenase activity|D-aldose:NAD+ 1-oxidoreductase activity|dehydrogenase, D-aldohexose											MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.121|RHEA:15917		molecular_function											owl:Class	
GO:0071894	biolink:NamedThing	histone H2B conserved C-terminal lysine ubiquitination	A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.	got7fsn_ti	fission yeast H2B K119 ubiquitination|budding yeast H2B K123 ubiquitination|mammalian H2B K120 ubiquitination						mah	2010-09-14T03:43:46Z						biological_process											owl:Class	
GO:0033523	biolink:NamedThing	histone H2B ubiquitination	The modification of histone H2B by addition of ubiquitin groups.	got7fsn_ti														biological_process											owl:Class	
GO:0006554	biolink:NamedThing	lysine catabolic process	The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.	got7fsn_ti	lysine catabolism|lysine degradation|lysine breakdown													biological_process											owl:Class	
GO:0102715	biolink:NamedThing	gibberellin A17,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A17 + 2-oxoglutarate + O2 <=> gibberellin A28 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-6546		molecular_function											owl:Class	
GO:0052820	biolink:NamedThing	DNA-1,N6-ethenoadenine N-glycosylase activity	Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar.	got7fsn_ti	1,N(6)-ethenoadenine N-glycosylase activity|1,N6-ethenoadenine glycosylase activity							2011-10-28T01:17:21Z						molecular_function											owl:Class	
GO:0102361	biolink:NamedThing	esculetin 4-O-beta-glucosyltransferase activity	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 4-O-beta-D-glucosyl-esculetin + UDP + H+.	got7fsn_ti												EC:2.4.1.126|MetaCyc:RXN-13471		molecular_function											owl:Class	
GO:0008977	biolink:NamedThing	prephenate dehydrogenase (NAD+) activity	Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH.	got7fsn_ti	chorismate mutase--prephenate dehydrogenase activity|hydroxyphenylpyruvate synthase activity|prephenate:NAD+ oxidoreductase (decarboxylating)											KEGG_REACTION:R01728|MetaCyc:PREPHENATEDEHYDROG-RXN|EC:1.3.1.12|RHEA:13869		molecular_function											owl:Class	
GO:0140080	biolink:NamedThing	class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity	Catalysis of the cleavage of an AP site 3' and 5' of the baseless site, generating a 3'-phosphate and a 5'-OH.	got7fsn_ti	endonuclease III|endonuclease IV						pg	2017-07-24T11:48:18Z						molecular_function											owl:Class	
GO:1900791	biolink:NamedThing	shamixanthone metabolic process	The chemical reactions and pathways involving shamixanthone.	got7fsn_ti	shamixanthone metabolism						di	2012-06-04T09:40:20Z						biological_process											owl:Class	
GO:0075285	biolink:NamedThing	sexual sporulation resulting in formation of a multicellular or syncytial spore	The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	got7fsn_ti														biological_process											owl:Class	
GO:0047277	biolink:NamedThing	globoside alpha-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.	got7fsn_ti	globoside acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase activity|forssman synthase activity|Forssman synthase activity|UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase activity											MetaCyc:2.4.1.88-RXN|RHEA:22164|EC:2.4.1.88		molecular_function											owl:Class	
GO:0018528	biolink:NamedThing	iminodiacetate dehydrogenase activity	Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine.	got7fsn_ti												UM-BBD_reactionID:r0589		molecular_function											owl:Class	
GO:0019713	biolink:NamedThing	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamine	The coupled methyl esterification and deamidation of peptidyl-glutamine.	got7fsn_ti	peptidyl-L-glutamic acid 5-methyl ester formation from glutamine|peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamine|peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamine											RESID:AA0072		biological_process											owl:Class	
GO:0098759	biolink:NamedThing	cellular response to interleukin-8	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.	got7fsn_ti	cellular response to IL-8													biological_process											owl:Class	
GO:0120178	biolink:NamedThing	steroid hormone biosynthetic process	The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.	got7fsn_ti							krc	2019-05-20T22:34:00Z						biological_process											owl:Class	
GO:0016920	biolink:NamedThing	pyroglutamyl-peptidase activity	Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.	got7fsn_ti												EC:3.4.19.-		molecular_function											owl:Class	
GO:0008955	biolink:NamedThing	peptidoglycan glycosyltransferase activity	Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.	got7fsn_ti	peptidoglycan transglycosylase activity|PG-II activity|bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase activity|undecaprenyldiphospho-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase activity|peptidoglycan TGase activity|penicillin binding protein (3 or 1B) activity											RHEA:23708|MetaCyc:RXN0-5405|EC:2.4.1.129		molecular_function											owl:Class	
GO:0097072	biolink:NamedThing	interferon regulatory factor 3 complex	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3.	got7fsn_ti	IRF3:IRF3 complex						pr	2011-06-15T04:26:10Z						cellular_component											owl:Class	
GO:0090385	biolink:NamedThing	phagosome-lysosome fusion	The creation of a phagolysosome from a phagosome and a lysosome.	got7fsn_ti							tb	2010-10-27T10:24:28Z						biological_process											owl:Class	
GO:0001882	biolink:NamedThing	nucleoside binding	Binding to a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.	got7fsn_ti														molecular_function											owl:Class	
GO:0008859	biolink:NamedThing	exoribonuclease II activity	Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction.	got7fsn_ti	RNase II|BN ribonuclease activity|Escherichia coli exo-RNase II|ribonuclease Q|ribonuclease II activity|5'-exoribonuclease activity|RNase II activity											EC:3.1.13.1|MetaCyc:3.1.13.1-RXN		molecular_function											owl:Class	
GO:0051865	biolink:NamedThing	protein autoubiquitination	The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.	got7fsn_ti	protein self-ubiquitination|protein auto-ubiquitination|protein autoubiquitinylation|protein auto-ubiquitinylation|protein self-ubiquitinylation													biological_process											owl:Class	
GO:0018848	biolink:NamedThing	pinocarveol isomerase activity	Catalysis of the reaction: pinocarveol = carveol.	got7fsn_ti												UM-BBD_reactionID:r0715|EC:5.5.1.-		molecular_function											owl:Class	
GO:0071244	biolink:NamedThing	cellular response to carbon dioxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.	got7fsn_ti							mah	2009-12-03T02:41:21Z						biological_process											owl:Class	
GO:0047079	biolink:NamedThing	deoxyuridine 1'-dioxygenase activity	Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = 2-deoxy-D-ribono-1,4-lactone + CO(2) + succinate + uracil.	got7fsn_ti	pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase activity|2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)|pyrimidine-deoxynucleoside 1'-dioxygenase activity											RHEA:23316|KEGG_REACTION:R02486|MetaCyc:1.14.11.10-RXN|EC:1.14.11.10		molecular_function											owl:Class	
GO:0014027	biolink:NamedThing	secondary neural tube rod cavitation	The process of medullary cavitation, which is the formation of a lumen in the medullary cord during secondary neurulation, producing the neural tube.	got7fsn_ti	medullary rod cavitation													biological_process											owl:Class	
GO:0102704	biolink:NamedThing	GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity	Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol.	got7fsn_ti												RHEA:29519|MetaCyc:RXN-5463|EC:2.4.1.257		molecular_function											owl:Class	
GO:0016422	biolink:NamedThing	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.	got7fsn_ti	S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity|messenger ribonucleate 2'-O-methyladenosine NG-methyltransferase activity|S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-6-N-)-methyltransferase activity											MetaCyc:2.1.1.62-RXN|EC:2.1.1.62|RHEA:22744		molecular_function											owl:Class	
GO:0008793	biolink:NamedThing	aromatic-amino-acid:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.	got7fsn_ti	aromatic amino acid transferase activity|aromatic amino acid aminotransferase activity|aromatic aminotransferase activity|ArAT|aromatic-amino-acid transaminase activity											EC:2.6.1.57|RHEA:17533|UM-BBD_reactionID:r0297|MetaCyc:2.6.1.57-RXN		molecular_function											owl:Class	
GO:0039557	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.	got7fsn_ti	inhibition of host IRF7 by virus|suppression by virus of host IRF7 activity|suppression by virus of host interferon regulatory factor 7 activity|inhibition of host interferon regulatory factor-7 by virus	https://github.com/geneontology/go-ontology/issues/21985			This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-03-09T04:17:46Z						biological_process											owl:Class	
GO:0090653	biolink:NamedThing	apical recycling endosome	Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells.	got7fsn_ti							tb	2015-07-01T15:46:19Z						cellular_component											owl:Class	
GO:0009337	biolink:NamedThing	sulfite reductase complex (NADPH)	A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide.	got7fsn_ti	sulphite reductase complex (NADPH)				See also the molecular function term 'sulfite reductase (NADPH) activity ; GO:0004783'.									cellular_component											owl:Class	
GO:0009778	biolink:NamedThing	cyclic photosynthetic phosphorylation	A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I.	got7fsn_ti														biological_process											owl:Class	
GO:0047965	biolink:NamedThing	glycoprotein O-fatty-acyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein.	got7fsn_ti	fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase activity|protein acyltransferase activity											MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN|EC:2.3.1.142		molecular_function											owl:Class	
GO:0018064	biolink:NamedThing	protein-L-histidine N-tele-methyltransferase activity	Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.	got7fsn_ti	protein (histidine) methyltransferase activity|S-adenosyl methionine:protein-histidine N-methyltransferase activity|S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase activity|protein-histidine N-methyltransferase activity|protein methylase IV activity|actin-specific histidine methyltransferase activity|peptidyl-histidine N-methyltransferase activity											EC:2.1.1.85|RHEA:19369|MetaCyc:2.1.1.85-RXN		molecular_function											owl:Class	
GO:0070080	biolink:NamedThing	titin Z domain binding	Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.	got7fsn_ti	Z repeat domain binding													molecular_function											owl:Class	
GO:0030761	biolink:NamedThing	8-hydroxyquercitin 8-O-methyltransferase activity	Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	flavonol 8-O-methyltransferase activity|S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase activity|flavonol 8-methyltransferase activity|8-hydroxyquercetin 8-O-methyltransferase activity											MetaCyc:2.1.1.88-RXN|KEGG_REACTION:R04398|RHEA:16593|EC:2.1.1.88		molecular_function											owl:Class	
GO:0080095	biolink:NamedThing	phosphatidylethanolamine-sterol O-acyltransferase activity	Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.	got7fsn_ti							dhl	2009-04-23T03:39:33Z						molecular_function											owl:Class	
GO:0019377	biolink:NamedThing	glycolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).	got7fsn_ti	glycolipid breakdown|glycolipid degradation|glycolipid catabolism													biological_process											owl:Class	
GO:0030581	biolink:NamedThing	symbiont intracellular protein transport in host	The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	intracellular protein transport in other organism during symbiotic interaction|intracellular protein transport in other organism involved in symbiotic interaction|intracellular protein transport in host|host cell protein transport										GO:0051708			biological_process											owl:Class	
GO:0070354	biolink:NamedThing	GATA2-TAL1-TCF3-Lmo2 complex	A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0030960	biolink:NamedThing	peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine	The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link.	got7fsn_ti												RESID:AA0368		biological_process											owl:Class	
GO:0016038	biolink:NamedThing	absorption of visible light	The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.	got7fsn_ti														biological_process											owl:Class	
GO:0031301	biolink:NamedThing	integral component of organelle membrane	The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to organelle membrane													cellular_component											owl:Class	
GO:0099085	biolink:NamedThing	DIF dechlorinase activity	Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-.	got7fsn_ti	DIF-1 dechlorinase activity|1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one 3(5)-dechlorinase activity|DIF-1 3(5)-dechlorinase activity|differentiation-inducing factor 1 dechlorinase activity|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one 3(5)-dechlorinase activity|differentiation-inducing factor dechlorinase activity													molecular_function											owl:Class	
GO:0044290	biolink:NamedThing	mitochondrial intracristal space	The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space.	got7fsn_ti							jl	2010-02-04T02:32:10Z				NIF_Subcellular:sao508958414		cellular_component											owl:Class	
GO:0034435	biolink:NamedThing	cholesterol esterification	A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.	got7fsn_ti														biological_process											owl:Class	
GO:0008970	biolink:NamedThing	phospholipase A1 activity	Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.	got7fsn_ti	phosphatidylcholine 1-acylhydrolase activity											RHEA:18689|Reactome:R-HSA-1482847|Reactome:R-HSA-1482920|Reactome:R-HSA-5694485|Reactome:R-HSA-1482862|MetaCyc:PHOSPHOLIPASE-A1-RXN|EC:3.1.1.32|Reactome:R-HSA-1482827|Reactome:R-HSA-1482932|Reactome:R-HSA-1482828|Reactome:R-HSA-1482892		molecular_function											owl:Class	
GO:0019333	biolink:NamedThing	denitrification pathway	The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen.	got7fsn_ti												MetaCyc:DENITRIFICATION-PWY		biological_process											owl:Class	
GO:0033785	biolink:NamedThing	heptose 7-phosphate kinase activity	Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.	got7fsn_ti	D-alpha,beta-D-heptose 7-phosphate 1-kinase activity											RHEA:27473|MetaCyc:RXN0-4341|EC:2.7.1.167		molecular_function											owl:Class	
GO:1901694	biolink:NamedThing	positive regulation of compound eye retinal cell apoptotic process	Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process.	got7fsn_ti	up regulation of compound eye retinal cell apoptotic process|activation of compound eye retinal cell apoptotic process|up-regulation of compound eye retinal cell apoptotic process|induction of compound eye retinal cell programmed cell death|upregulation of compound eye retinal cell apoptotic process						pr	2012-12-12T10:28:45Z			GO:0046675			biological_process											owl:Class	
GO:0046672	biolink:NamedThing	positive regulation of compound eye retinal cell programmed cell death	Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.	got7fsn_ti	up regulation of retinal cell programmed cell death|up-regulation of retinal cell programmed cell death|activation of retinal cell programmed cell death|stimulation of retinal cell programmed cell death|upregulation of retinal cell programmed cell death|positive regulation of retinal cell programmed cell death													biological_process											owl:Class	
GO:0019930	biolink:NamedThing	cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid	The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.	got7fsn_ti	cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester anabolism from peptidyl-aspartic acid|cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester synthesis from peptidyl-aspartic acid|cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester formation from peptidyl-aspartic acid											RESID:AA0316		biological_process											owl:Class	
GO:0042769	biolink:NamedThing	DNA damage response, detection of DNA damage	The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal.	got7fsn_ti	detection of DNA damage during DNA damage response|DNA damage response, perception of DNA damage													biological_process											owl:Class	
GO:0070311	biolink:NamedThing	nucleosomal methylation activator complex	A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription.	got7fsn_ti	NUMAC													cellular_component											owl:Class	
GO:0019273	biolink:NamedThing	L-alanine biosynthetic process via ornithine	The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine.	got7fsn_ti	L-alanine synthesis via ornithine|L-alanine formation via ornithine|L-alanine anabolism via ornithine													biological_process											owl:Class	
GO:0042852	biolink:NamedThing	L-alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.	got7fsn_ti	L-alanine formation|L-alanine biosynthesis|L-alanine synthesis|L-alanine anabolism													biological_process											owl:Class	
GO:0010674	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter, meiotic|positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|activation of meiosis by negative regulation of transcription from RNA polymerase II promoter|up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter						dgf	2012-05-01T08:39:58Z			GO:1900475			biological_process											owl:Class	
GO:0050408	biolink:NamedThing	[pyruvate kinase]-phosphatase activity	Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate.	got7fsn_ti	pyruvate kinase phosphatase activity|ATP:pyruvate 2-O-phosphotransferase-phosphate phosphohydrolase activity|pyruvate kinase-phosphatase activity											EC:3.1.3.49|MetaCyc:PYRUVATE-KINASE-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:1990352	biolink:NamedThing	BRE1 E3 ubiquitin ligase complex	A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes.	got7fsn_ti	BRE1 oligomer|BRE1 E3 ubiquitin-protein ligase complex				An example of this is BRE1 in Saccharomyces cerevisiae (UniProt symbol Q07457) in PMID:19531475 (inferred from direct assay).		bhm	2014-03-27T13:49:05Z						cellular_component											owl:Class	
GO:0016608	biolink:NamedThing	growth hormone-releasing hormone activity	The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland.	got7fsn_ti	GHRH activity|GHRF activity													molecular_function											owl:Class	
GO:0043481	biolink:NamedThing	anthocyanin accumulation in tissues in response to UV light	The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0032264	biolink:NamedThing	IMP salvage	Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0051991	biolink:NamedThing	UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity	Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP.	got7fsn_ti					Note that EC classifies 'UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity ; GO:0051991' and 'undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity ; GO:0050511' under the same EC number, EC:2.4.1.227.		ai	2010-07-06T11:53:19Z				MetaCyc:NACGLCTRANS-RXN|RHEA:31227|EC:2.4.1.227		molecular_function											owl:Class	
GO:0033434	biolink:NamedThing	AUC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AUC codon.	got7fsn_ti	ATC codon-amino acid adaptor activity|isoleucine tRNA				Note that in the standard genetic code, ATC codes for isoleucine.									molecular_function											owl:Class	
GO:0061007	biolink:NamedThing	hepaticobiliary system process	An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.	got7fsn_ti	hepatobiliary system process						dph	2010-01-22T09:09:10Z						biological_process											owl:Class	
GO:0071594	biolink:NamedThing	thymocyte aggregation	The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules.	got7fsn_ti	immature T-cell aggregation|immature T cell aggregation|immature T-lymphocyte aggregation|thymic lymphocyte aggregation|T cell precursor aggregation						mah	2010-01-29T01:38:49Z						biological_process											owl:Class	
GO:0061865	biolink:NamedThing	polarized secretion of basement membrane proteins in epithelium	The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium.	got7fsn_ti							dph	2017-04-07T18:26:02Z						biological_process											owl:Class	
GO:0018824	biolink:NamedThing	(hydroxyamino)benzene mutase activity	Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol.	got7fsn_ti	HAB mutase activity|hydroxylaminobenzene mutase activity|(hydroxyamino)benzene hydroxymutase activity|hydroxylaminobenzene hydroxymutase activity											UM-BBD_reactionID:r0304|RHEA:19245|MetaCyc:5.4.4.1-RXN		molecular_function											owl:Class	
GO:0071846	biolink:NamedThing	actin filament debranching	An actin filament severing process that results in the removal of actin filament branches specifically at the branch points.	got7fsn_ti							mah	2010-09-10T02:15:42Z						biological_process											owl:Class	
GO:0051014	biolink:NamedThing	actin filament severing	The process in which an actin filament is broken down into smaller filaments.	got7fsn_ti	actin filament severing activity|F-actin severing|barbed-end actin capping/severing activity													biological_process											owl:Class	
GO:0001717	biolink:NamedThing	conversion of seryl-tRNAsec to selenocys-tRNAsec	The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine.	got7fsn_ti														biological_process											owl:Class	
GO:0044066	biolink:NamedThing	modification by symbiont of host cell nucleus	The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus.	got7fsn_ti	modification of host nucleus by symbiont|modification of host cell nucleus by symbiont|modification by symbiont of host nucleus													biological_process											owl:Class	
GO:0045324	biolink:NamedThing	late endosome to vacuole transport	The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.	got7fsn_ti														biological_process											owl:Class	
GO:0052598	biolink:NamedThing	histamine oxidase activity	Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+.	got7fsn_ti	1H-Imidazole-4-ethanamine oxidase activity|histamine:oxygen oxidoreductase (deaminating) activity|1H-Imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) activity											RHEA:25625|Reactome:R-HSA-5696131|EC:1.4.3.22|MetaCyc:RXN-9600|KEGG_REACTION:R02150		molecular_function											owl:Class	
GO:0090383	biolink:NamedThing	phagosome acidification	Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.	got7fsn_ti	phagosomal acidification						tb	2010-10-27T10:20:22Z						biological_process											owl:Class	
GO:0046378	biolink:NamedThing	enterobacterial common antigen metabolic process	The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.	got7fsn_ti	enterobacterial common antigen metabolism													biological_process											owl:Class	
GO:0102645	biolink:NamedThing	17(E)-cheilanthenediol synthase activity	Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O.	got7fsn_ti												MetaCyc:RXN-15758		molecular_function											owl:Class	
GO:1990644	biolink:NamedThing	microtubule site clamp	The binding activity of a molecule that attaches the spindle microtubules to the kinetochore.	got7fsn_ti							vw	2015-02-13T15:50:13Z						molecular_function											owl:Class	
GO:0044828	biolink:NamedThing	negative regulation by host of viral genome replication	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication.	got7fsn_ti							jl	2014-02-06T11:34:23Z						biological_process											owl:Class	
GO:0110055	biolink:NamedThing	negative regulation of actin filament annealing	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.	got7fsn_ti							kmv	2017-09-20T20:10:55Z						biological_process											owl:Class	
GO:0035492	biolink:NamedThing	negative regulation of leukotriene production involved in inflammatory response	Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.	got7fsn_ti							bf	2010-04-26T10:50:55Z						biological_process											owl:Class	
GO:0047593	biolink:NamedThing	6-acetylglucose deacetylase activity	Catalysis of the reaction: 6-acetyl-D-glucose + H(2)O = D-glucose + acetate + H(+).	got7fsn_ti	6-acetyl-D-glucose acetylhydrolase activity|6-O-acetylglucose deacetylase activity											EC:3.1.1.33|KEGG_REACTION:R00327|RHEA:18485|MetaCyc:6-ACETYLGLUCOSE-DEACETYLASE-RXN		molecular_function											owl:Class	
GO:0006753	biolink:NamedThing	nucleoside phosphate metabolic process	The chemical reactions and pathways involving any phosphorylated nucleoside.	got7fsn_ti	nucleoside phosphate metabolism													biological_process											owl:Class	
GO:0004561	biolink:NamedThing	alpha-N-acetylglucosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.	got7fsn_ti	NAG activity|alpha-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase activity|alpha-D-2-acetamido-2-deoxyglucosidase activity|N-acetyl-alpha-glucosaminidase activity|N-acetyl-alpha-D-glucosaminidase activity|alpha-acetylglucosaminidase activity											MetaCyc:3.2.1.50-RXN|EC:3.2.1.50|Reactome:R-HSA-2090038|Reactome:R-HSA-1678742|Reactome:R-HSA-9036052|Reactome:R-HSA-2263496		molecular_function											owl:Class	
GO:0097517	biolink:NamedThing	contractile actin filament bundle	An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.	got7fsn_ti							pr	2013-10-16T15:41:14Z						cellular_component											owl:Class	
GO:0006768	biolink:NamedThing	biotin metabolic process	The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.	got7fsn_ti	vitamin H metabolic process|vitamin H metabolism|biotin metabolism|vitamin B7 metabolism|vitamin B7 metabolic process											Wikipedia:Biotin		biological_process											owl:Class	
GO:0047160	biolink:NamedThing	alkylglycerophosphate 2-O-acetyltransferase activity	Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA.	got7fsn_ti	acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase activity|alkyllyso-GP:acetyl-CoA acetyltransferase activity											MetaCyc:2.3.1.105-RXN|RHEA:18557|KEGG_REACTION:R03455|EC:2.3.1.105		molecular_function											owl:Class	
GO:0001586	biolink:NamedThing	Gi/o-coupled serotonin receptor activity	Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.	got7fsn_ti	serotonin receptor activity, coupled via Gi/o|5-HT1 receptor activity													molecular_function											owl:Class	
GO:0042139	biolink:NamedThing	early meiotic recombination nodule assembly	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene.	got7fsn_ti														biological_process											owl:Class	
GO:0004494	biolink:NamedThing	methylmalonyl-CoA mutase activity	Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA.	got7fsn_ti	(R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase activity|methylmalonyl coenzyme A mutase activity|methylmalonyl-CoA CoA-carbonyl mutase activity|(R)-methylmalonyl-CoA CoA-carbonylmutase activity|methylmalonyl coenzyme A carbonylmutase activity|(S)-methylmalonyl-CoA mutase activity											RHEA:22888|Reactome:R-HSA-3322971|Reactome:R-HSA-71010|KEGG_REACTION:R00833|EC:5.4.99.2|MetaCyc:METHYLMALONYL-COA-MUT-RXN|UM-BBD_reactionID:r0922		molecular_function											owl:Class	
GO:0034810	biolink:NamedThing	4,5-dihydroxybenzo(a)pyrene dioxygenase activity	Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate.	got7fsn_ti												UM-BBD_reactionID:r1128|EC:1.13.11.-		molecular_function											owl:Class	
GO:0004807	biolink:NamedThing	triose-phosphate isomerase activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.	got7fsn_ti	triose phosphate mutase activity|D-glyceraldehyde-3-phosphate aldose-ketose-isomerase activity|triose phosphoisomerase activity|triosephosphate mutase activity|D-glyceraldehyde-3-phosphate ketol-isomerase activity|phosphotriose isomerase activity|triosephosphate isomerase activity											Reactome:R-HSA-70481|EC:5.3.1.1|MetaCyc:TRIOSEPISOMERIZATION-RXN|RHEA:18585|KEGG_REACTION:R01015|Reactome:R-HSA-70454		molecular_function											owl:Class	
GO:0002383	biolink:NamedThing	immune response in brain or nervous system	An immune response taking place in the brain or nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0016474	biolink:NamedThing	sodium ion-transporting V-type ATPase complex	A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis.	got7fsn_ti	sodium-translocating V-type ATPase complex													cellular_component											owl:Class	
GO:0006298	biolink:NamedThing	mismatch repair	A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.	got7fsn_ti	mismatch repair, MutL-like pathway|MMR|MutS/MutL/MutH pathway|long patch mismatch repair system										GO:0006300	Wikipedia:DNA_mismatch_repair		biological_process											owl:Class	
GO:0032408	biolink:NamedThing	MutSbeta complex binding	Binding to a MutSbeta mismatch repair complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0004754	biolink:NamedThing	saccharopine dehydrogenase (NAD+, L-lysine-forming) activity	Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = 2-oxoglutarate + L-lysine + H(+) + NADH.	got7fsn_ti	N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)|epsilon-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)|dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming)|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)|N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming)											RHEA:12440|EC:1.5.1.7|KEGG_REACTION:R00715|MetaCyc:1.5.1.7-RXN		molecular_function											owl:Class	
GO:0032281	biolink:NamedThing	AMPA glutamate receptor complex	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.	got7fsn_ti	AMPA receptor|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|AMPA-selective glutamate receptor complex													cellular_component											owl:Class	
GO:0006425	biolink:NamedThing	glutaminyl-tRNA aminoacylation	The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:2000075	biolink:NamedThing	negative regulation of cytokinesis, site selection	Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.	got7fsn_ti	negative regulation of site selection involved in cell cycle cytokinesis						tb	2010-08-27T11:19:56Z						biological_process											owl:Class	
GO:0016756	biolink:NamedThing	glutathione gamma-glutamylcysteinyltransferase activity	Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.	got7fsn_ti	glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase activity|phytochelatin synthase activity|gamma-glutamylcysteine dipeptidyl transpeptidase activity										GO:0042143	EC:2.3.2.15|MetaCyc:2.3.2.15-RXN|RHEA:17917		molecular_function											owl:Class	
GO:0101011	biolink:NamedThing	inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 1-diphosphatase activity	Catalysis of the reaction: myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = myo-inositol hexakisphosphate + phosphate.	got7fsn_ti	inositol 1-pyrophosphate 2,3,4,5,6-pentakisphosphate 1-pyrophosphatase activity													molecular_function											owl:Class	
GO:0034683	biolink:NamedThing	integrin alphav-beta3 complex	An integrin complex that comprises one alphav subunit and one beta3 subunit.	got7fsn_ti	ITGAV-ITGB3 complex|alphav-beta3 integrin complex													cellular_component											owl:Class	
GO:0043251	biolink:NamedThing	sodium-dependent organic anion transport	The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0015711	biolink:NamedThing	organic anion transport	The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.	got7fsn_ti														biological_process											owl:Class	
GO:0070514	biolink:NamedThing	SRF-myogenin-E12 complex	A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.	got7fsn_ti														cellular_component											owl:Class	
GO:0008257	biolink:NamedThing	protein histidine tele-kinase activity	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine.	got7fsn_ti	ATP:protein-L-histidine Ntau-phosphotransferase activity|protein-histidine tele-kinase activity|ATP:protein-L-histidine N-tele-phosphotransferase activity|HK3											RHEA:11860|MetaCyc:2.7.13.2-RXN|EC:2.7.13.2		molecular_function											owl:Class	
GO:0002480	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.	got7fsn_ti	TAP-independent exogenous peptide antigen processing and presentation via MHC class I|cross-presentation|cross presentation|exogenous peptide antigen processing and presentation via MHC class I, TAP-independent|TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I													biological_process											owl:Class	
GO:0050410	biolink:NamedThing	3-oxolaurate decarboxylase activity	Catalysis of the reaction: 3-oxolaurate + H(+) = 2-undecanone + CO(2).	got7fsn_ti	3-oxododecanoate carboxy-lyase activity|beta-ketoacyl decarboxylase activity|beta-ketolaurate decarboxylase activity|3-oxododecanoate carboxy-lyase (2-undecanone-forming)											MetaCyc:3-OXOLAURATE-DECARBOXYLASE-RXN|KEGG_REACTION:R03747|EC:4.1.1.56|RHEA:13385		molecular_function											owl:Class	
GO:0008683	biolink:NamedThing	2-oxoglutarate decarboxylase activity	Catalysis of the reaction: 2-oxoglutarate + H(+) = CO(2) + succinate semialdehyde.	got7fsn_ti	2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)|alpha-ketoglutaric decarboxylase activity|pre-2-oxoglutarate decarboxylase activity|2-oxoglutarate carboxy-lyase activity|alpha-ketoglutarate decarboxylase activity											KEGG_REACTION:R00272|EC:4.1.1.71|RHEA:10524|MetaCyc:RXN-7774		molecular_function											owl:Class	
GO:0018784	biolink:NamedThing	(S)-2-haloacid dehalogenase activity	Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.	got7fsn_ti	2-halocarboxylic acid dehalogenase II activity|DL-2-haloacid dehalogenase activity|(S)-2-haloacid halidohydrolase activity|2-haloacid dehalogenase activity|L-DEX activity|2-haloacid halidohydrolase activity|2-haloalkanoid acid halidohydrolase activity|halocarboxylic acid halidohydrolase activity|2-haloalkanoic acid dehalogenase activity|L-2-haloacid dehalogenase activity											EC:3.8.1.2|UM-BBD_reactionID:r0090|RHEA:11192|MetaCyc:2-HALOACID-DEHALOGENASE-RXN		molecular_function											owl:Class	
GO:0030519	biolink:NamedThing	snoRNP binding	Binding to a small nucleolar ribonucleoprotein particle.	got7fsn_ti														molecular_function											owl:Class	
GO:0030612	biolink:NamedThing	arsenate reductase (thioredoxin) activity	Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin.	got7fsn_ti												MetaCyc:RXN-10737		molecular_function											owl:Class	
GO:0048454	biolink:NamedThing	sepal structural organization	The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	sepal structural organisation										GO:0048424			biological_process											owl:Class	
GO:1902023	biolink:NamedThing	L-arginine transport	The directed movement of a L-arginine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-arginine uptake|L-arginine import						kmv	2013-03-27T16:09:11Z			GO:0043091			biological_process											owl:Class	
GO:0015802	biolink:NamedThing	basic amino acid transport	The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0035871	biolink:NamedThing	protein K11-linked deubiquitination	A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.	got7fsn_ti	protein K11-linked deubiquitylation|protein K11-linked deubiquitinylation						bf	2011-05-26T11:44:13Z						biological_process											owl:Class	
GO:0009304	biolink:NamedThing	tRNA transcription	The synthesis of transfer RNA (tRNA) from a DNA template.	got7fsn_ti	tRNA synthesis|tRNA biosynthesis|tRNA biosynthetic process													biological_process											owl:Class	
GO:0008901	biolink:NamedThing	ferredoxin hydrogenase activity	Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.	got7fsn_ti	[Fe] hydrogenase gamma|hydrogenase II|Ni-Fe-Se hydrogenase activity|hydrogenase I|hydrogenlyase activity|[Fe] hydrogenase activity|uptake hydrogenase activity|Ni-Fe hydrogenase activity|H(2) oxidizing hydrogenase activity|nickel-iron hydrogenase activity|H(2) producing hydrogenase activity|iron hydrogenase activity|H2 oxidizing hydrogenase|bidirectional hydrogenase activity|hydrogenase (ferredoxin) activity|hydrogenase activity|hydrogen-lyase activity|nickel hydrogenase activity|iron-only hydrogenase activity|nickel-iron-selenium hydrogenase activity|H2 producing hydrogenase|hydrogen:ferredoxin oxidoreductase activity				Note that this function was formerly EC:1.12.1.1, EC:1.12.7.1, EC:1.98.1.1, EC:1.18.3.1 and EC:1.18.99.1.						GO:0016951|GO:0016948|GO:0016950|GO:0016949	EC:1.12.7.2|RHEA:17445|MetaCyc:HYDROG-RXN|UM-BBD_enzymeID:e0418		molecular_function											owl:Class	
GO:0015330	biolink:NamedThing	high-affinity glutamine transmembrane transporter activity	Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity glutamine permease activity|high affinity glutamine transmembrane transporter activity													molecular_function											owl:Class	
GO:0018406	biolink:NamedThing	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring.	got7fsn_ti	protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan|protein amino acid C-linked mannosylation										GO:0032004	RESID:AA0217		biological_process											owl:Class	
GO:0060214	biolink:NamedThing	endocardium formation	Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	got7fsn_ti														biological_process											owl:Class	
GO:0031389	biolink:NamedThing	Rad17 RFC-like complex	A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.	got7fsn_ti	Rad24p RFC-like complex|RFC (Rad17)|Rad17-RFC|Rad17-RLC													cellular_component											owl:Class	
GO:0102574	biolink:NamedThing	3-oxo-myristoyl-ACP hydrolase activity	Catalysis of the reaction: H2O + a 3-oxo-myristoyl-[acp] = 3-oxo-myristate + H+ + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-15280		molecular_function											owl:Class	
GO:0106219	biolink:NamedThing	zinc ion sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of zinc.	got7fsn_ti							hjd	2019-08-15T16:45:43Z						molecular_function											owl:Class	
GO:0044611	biolink:NamedThing	nuclear pore inner ring	A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex.	got7fsn_ti	Nup170 complex						jl	2012-06-20T01:14:17Z						cellular_component											owl:Class	
GO:0031395	biolink:NamedThing	bursicon neuropeptide hormone complex	A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits.	got7fsn_ti														cellular_component											owl:Class	
GO:0051561	biolink:NamedThing	positive regulation of mitochondrial calcium ion concentration	Any process that increases the concentration of calcium ions in mitochondria.	got7fsn_ti	mitochondrial calcium ion concentration elevation|elevation of calcium ion concentration in mitochondrion|elevation of mitochondrial calcium ion concentration|elevation of calcium ion concentration in mitochondria													biological_process											owl:Class	
GO:0021816	biolink:NamedThing	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration	The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells.	got7fsn_ti														biological_process											owl:Class	
GO:0097602	biolink:NamedThing	cullin family protein binding	Binding to a member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3).	got7fsn_ti	cullin binding						pr	2014-05-11T20:41:10Z						molecular_function											owl:Class	
GO:0000250	biolink:NamedThing	lanosterol synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.	got7fsn_ti	2,3-epoxysqualene--lanosterol cyclase activity|squalene-2,3-oxide-lanosterol cyclase activity|squalene epoxidase-cyclase activity|oxidosqualene:lanosterol cyclase activity|2,3-epoxysqualene-lanosterol cyclase activity|2,3-oxidosqualene sterol cyclase activity|(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)|2,3-oxidosqualene-lanosterol cyclase activity|OSC|oxidosqualene--lanosterol cyclase activity|lanosterol 2,3-oxidosqualene cyclase activity|squalene 2,3-epoxide:lanosterol cyclase activity|2,3-epoxysqualene lanosterol cyclase activity|oxidosqualene-lanosterol cyclase activity											RHEA:14621|MetaCyc:LANOSTEROL-SYNTHASE-RXN|EC:5.4.99.7|KEGG_REACTION:R03199|Reactome:R-HSA-191366		molecular_function											owl:Class	
GO:0070441	biolink:NamedThing	G-protein beta/gamma-Btk complex	A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein.	got7fsn_ti	G protein complex (BTK, GNG1, GNG2)|G protein complex (Btk, Gng2, Gnb1)				See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'.									cellular_component											owl:Class	
GO:0033707	biolink:NamedThing	3''-deamino-3''-oxonicotianamine reductase activity	Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+.	got7fsn_ti	2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity											MetaCyc:1.1.1.285-RXN|EC:1.1.1.285		molecular_function											owl:Class	
GO:0000237	biolink:NamedThing	leptotene	The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).							Wikipedia:Leptotene|Wikipedia:Meiosis#Leptotene		biological_process											owl:Class	
GO:0002201	biolink:NamedThing	somatic diversification of DSCAM-based immune receptors	The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects.	got7fsn_ti					Note that this type of immune receptor may not be limited to insects.									biological_process											owl:Class	
GO:0062191	biolink:NamedThing	galactoxylomannan biosynthetic process	The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.	got7fsn_ti	glucuronoxylomannogalactan biosynthetic process|galactoxylomannan formation|galactoxylomannan synthesis|GalXM biosynthetic process|galactoxylomannan anabolism|galactoxylomannan biosynthesis						dph	2019-12-06T14:44:36Z						biological_process											owl:Class	
GO:0008712	biolink:NamedThing	ADP-glyceromanno-heptose 6-epimerase activity	Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose.	got7fsn_ti	ADPglyceromanno-heptose 6-epimerase activity|ADP-L-glycero-D-manno-heptose 6-epimerase activity											KEGG_REACTION:R05176|MetaCyc:5.1.3.20-RXN|EC:5.1.3.20|RHEA:17577		molecular_function											owl:Class	
GO:0070684	biolink:NamedThing	seminal clot liquefaction	The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.	got7fsn_ti	semen liquefaction						mah	2009-06-02T04:33:54Z						biological_process											owl:Class	
GO:0097358	biolink:NamedThing	D-leucyl-tRNA(Leu) deacylase activity	Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu).	got7fsn_ti							pr	2012-07-04T09:18:12Z						molecular_function											owl:Class	
GO:0102808	biolink:NamedThing	pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + pelargonidin 3-O-beta-D-glucoside <=> H+ + pelargonidin 3-O-sophoroside + UDP.	got7fsn_ti												MetaCyc:RXN-8177		molecular_function											owl:Class	
GO:0045442	biolink:NamedThing	deacetoxycephalosporin-C hydroxylase activity	Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O(2) = CO(2) + deacetylcephalosporin C + succinate.	got7fsn_ti	DACS|deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|deacetylcephalosporin C synthase activity|deacetoxycephalosporin C hydroxylase activity|3'-methylcephem hydroxylase activity|beta-lactam hydroxylase activity|DAOC hydroxylase activity											EC:1.14.11.26|RHEA:16805|MetaCyc:1.14.11.26-RXN|KEGG_REACTION:R05229		molecular_function											owl:Class	
GO:0003187	biolink:NamedThing	ventriculo bulbo valve morphogenesis	The process in which the structure of the ventriculo bulbo valve is generated and organized.	got7fsn_ti							dph	2009-10-08T12:07:00Z						biological_process											owl:Class	
GO:0052902	biolink:NamedThing	spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity	Catalysis of the reaction: H(2)O + O(2) + spermidine = 3-aminopropanal + H(2)O(2) + putrescine.	got7fsn_ti	polyamine oxidase activity|non-specific polyamine oxidase activity|N(1)-acetylpolyamine oxidase activity											KEGG_REACTION:R09077|RHEA:25808|MetaCyc:RXN-10461|EC:1.5.3.17|MetaCyc:RXN-12089|EC:1.5.3.13		molecular_function											owl:Class	
GO:0140458	biolink:NamedThing	pre-transcriptional gene silencing by RNA	Any gene inactivation (silencing) process mediated by small RNA molecules that occur before the trancription begins.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19328					pg	2020-04-24T07:19:09Z						biological_process											owl:Class	
GO:1990150	biolink:NamedThing	VEGF-A complex	A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase.	got7fsn_ti	vascular endothelial growth factor A complex						bhm	2013-07-30T13:24:41Z						cellular_component											owl:Class	
GO:0004340	biolink:NamedThing	glucokinase activity	Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.	got7fsn_ti	glucokinase (phosphorylating)|ATP:D-glucose 6-phosphotransferase activity|glucose kinase activity											EC:2.7.1.2|Reactome:R-HSA-5621918|RHEA:17825|Reactome:R-HSA-70420|Reactome:R-HSA-5621888|MetaCyc:GLUCOKIN-RXN		molecular_function											owl:Class	
GO:0042117	biolink:NamedThing	monocyte activation	The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti														biological_process											owl:Class	
GO:0047044	biolink:NamedThing	androstan-3-alpha,17-beta-diol dehydrogenase activity	Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.	got7fsn_ti	20beta-HSD|3alpha(or 20beta)-hydroxysteroid dehydrogenase activity|dehydrogenase, 20beta-hydroxy steroid|(R)-20-hydroxysteroid dehydrogenase activity|3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity|20beta-hydroxysteroid dehydrogenase activity|cortisone reductase activity|delta4-3-ketosteroid hydrogenase activity|NADH-20beta-hydroxysteroid dehydrogenase activity|3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity|3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity											RHEA:22400|EC:1.1.1.53|MetaCyc:1.1.1.53-RXN		molecular_function											owl:Class	
GO:0052755	biolink:NamedThing	reduced coenzyme F420:quinone oxidoreductase activity	Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone.	got7fsn_ti	F420H2-dependent quinone oxidoreductase activity|F420H2:2,3-dimethyl-1,4-naphthoquinone oxidoreductase activity|F420H2:quinone oxidoreductase activity						ai	2011-09-22T04:08:13Z						molecular_function											owl:Class	
GO:0052857	biolink:NamedThing	NADPHX epimerase activity	Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX.	got7fsn_ti												Reactome:R-HSA-6806966|RHEA:32227|EC:5.1.99.6		molecular_function											owl:Class	
GO:0048788	biolink:NamedThing	cytoskeleton of presynaptic active zone	The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.	got7fsn_ti	synaptic ribbon|pre-synaptic ribbon|pre-synaptic cytoskeletal matrix assembled at active zones|T-bar ribbon|active zone cytomatrix|pre-synaptic dense body|CAZ|presynaptic cytoskeletal matrix assembled at active zones|T-bar|ribbon|presynaptic ribbon|presynaptic dense body|presynaptic cytoskeletal matrix|presynaptic cytomatrix assembled at active zones											NIF_Subcellular:sao1470121605		cellular_component											owl:Class	
GO:0097276	biolink:NamedThing	cellular creatinine homeostasis	Any biological process involved in the maintenance of an internal steady state of creatinine at the level of the cell.	got7fsn_ti							pr	2012-03-22T02:55:46Z						biological_process											owl:Class	
GO:0070580	biolink:NamedThing	base J metabolic process	The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J.	got7fsn_ti	base J metabolism|beta-D-glucosyl-HOMedU metabolic process|beta-D-glucosyl-hydroxymethyluracil metabolism						mah	2009-04-22T02:37:23Z						biological_process											owl:Class	
GO:0075511	biolink:NamedThing	macropinosome lysis involved in viral entry into host cell	Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm.	got7fsn_ti							jl	2011-07-27T11:38:07Z						biological_process											owl:Class	
GO:0001648	biolink:NamedThing	proteinase activated receptor activity	A G protein-coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0005402	biolink:NamedThing	carbohydrate:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in).	got7fsn_ti	cation:sugar symporter activity|cation/sugar symporter activity|sugar:cation symporter activity													molecular_function											owl:Class	
GO:0000006	biolink:NamedThing	high-affinity zinc transmembrane transporter activity	Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity zinc uptake transmembrane transporter activity|high-affinity zinc uptake transmembrane transporter activity													molecular_function											owl:Class	
GO:0046987	biolink:NamedThing	N-acetyllactosamine beta-1,3-glucuronosyltransferase activity	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine).	got7fsn_ti	galactosyl beta-1,4 N-acetylglucosamine beta-1,3 glucuronosyltransferase activity													molecular_function											owl:Class	
GO:0043237	biolink:NamedThing	laminin-1 binding	Binding to laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1.	got7fsn_ti	laminin-111 binding													molecular_function											owl:Class	
GO:0047614	biolink:NamedThing	aconitate delta-isomerase activity	Catalysis of the reaction: trans-aconitate = cis-aconitate.	got7fsn_ti	aconitate D-isomerase activity|aconitate delta2-delta3-isomerase activity|aconitate isomerase activity											MetaCyc:ACONITATE-DELTA-ISOMERASE-RXN|KEGG_REACTION:R02244|RHEA:17265|EC:5.3.3.7		molecular_function											owl:Class	
GO:0014703	biolink:NamedThing	oscillatory muscle contraction	A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation.	got7fsn_ti														biological_process											owl:Class	
GO:0003010	biolink:NamedThing	voluntary skeletal muscle contraction	A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control.	got7fsn_ti														biological_process											owl:Class	
GO:0031843	biolink:NamedThing	type 2 neuropeptide Y receptor binding	Binding to a type 2 neuropeptide Y receptor.	got7fsn_ti	type 2 neuropeptide Y receptor ligand													molecular_function											owl:Class	
GO:0043164	biolink:NamedThing	Gram-negative-bacterium-type cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane.	got7fsn_ti	1-2nm peptidoglycan-based cell wall biogenesis|cell wall biosynthetic process|cell wall synthesis|cell wall anabolism|cell wall formation|cell wall assembly													biological_process											owl:Class	
GO:0098873	biolink:NamedThing	neuronal action potential back-propagation	Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma.	got7fsn_ti														biological_process											owl:Class	
GO:0036406	biolink:NamedThing	anchored component of periplasmic side of cell outer membrane	The component of the cell outer membrane consisting of gene products and protein complexes that are tethered to the periplasmic side of membrane by only a covalently attached anchor, embedded in the periplasmic side of the membrane only.	got7fsn_ti	anchored to internal side of cell outer membrane|anchored to periplasmic side of cell outer membrane						bf	2013-08-15T11:45:39Z						cellular_component											owl:Class	
GO:0051289	biolink:NamedThing	protein homotetramerization	The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.	got7fsn_ti	protein homotetramer assembly|protein homotetramer biosynthetic process|protein homotetramer formation|protein homotetramer biosynthesis													biological_process											owl:Class	
GO:0033440	biolink:NamedThing	ACG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an ACG codon.	got7fsn_ti	threonine tRNA				Note that in the standard genetic code, ACG codes for threonine.									molecular_function											owl:Class	
GO:0000407	biolink:NamedThing	phagophore assembly site	Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.	got7fsn_ti	PAS|perivacuolar space|pre-autophagosomal structure													cellular_component											owl:Class	
GO:0098570	biolink:NamedThing	stromal side of plastid inner membrane	The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.	got7fsn_ti														cellular_component											owl:Class	
GO:0043841	biolink:NamedThing	(S)-lactate 2-kinase activity	Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP.	got7fsn_ti	lactate 2-kinase activity											MetaCyc:RXN-8076		molecular_function											owl:Class	
GO:0060252	biolink:NamedThing	positive regulation of glial cell proliferation	Any process that activates or increases the rate or extent of glial cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0033815	biolink:NamedThing	biphenyl synthase activity	Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2.	got7fsn_ti	malonyl-CoA:benzoyl-CoA malonyltransferase activity|BIS											MetaCyc:2.3.1.177-RXN|RHEA:22292|EC:2.3.1.177		molecular_function											owl:Class	
GO:0120209	biolink:NamedThing	cone telodendria	Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.	got7fsn_ti							krc	2019-05-21T00:01:34Z						cellular_component											owl:Class	
GO:0035446	biolink:NamedThing	cysteine-glucosaminylinositol ligase activity	Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.	got7fsn_ti	L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase|desacetylmycothiol synthase|MshC ligase						bf	2010-04-14T11:33:06Z				EC:6.3.1.13|RHEA:26176|MetaCyc:RXN1G-4		molecular_function											owl:Class	
GO:0001933	biolink:NamedThing	negative regulation of protein phosphorylation	Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.	got7fsn_ti	down regulation of protein amino acid phosphorylation|down-regulation of protein amino acid phosphorylation|negative regulation of protein amino acid phosphorylation|inhibition of protein amino acid phosphorylation|downregulation of protein amino acid phosphorylation													biological_process											owl:Class	
GO:0031435	biolink:NamedThing	mitogen-activated protein kinase kinase kinase binding	Binding to a mitogen-activated protein kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase.	got7fsn_ti	MAPKKK binding													molecular_function											owl:Class	
GO:0035887	biolink:NamedThing	aortic smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.	got7fsn_ti							bf	2011-06-08T11:34:26Z						biological_process											owl:Class	
GO:0060591	biolink:NamedThing	chondroblast differentiation	The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.	got7fsn_ti	chondrocyte progenitor cell differentiation						dph	2009-05-11T07:47:36Z						biological_process											owl:Class	
GO:0031625	biolink:NamedThing	ubiquitin protein ligase binding	Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.	got7fsn_ti	ubiquitin ligase binding													molecular_function											owl:Class	
GO:0047045	biolink:NamedThing	testosterone 17-beta-dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.	got7fsn_ti	testosterone 17beta-dehydrogenase (NADP+)|17beta-hydroxysteroid:NADP+ 17-oxidoreductase activity|NADP-dependent testosterone-17beta-oxidoreductase activity|17-ketoreductase activity											MetaCyc:1.1.1.64-RXN|RHEA:14981|EC:1.1.1.64|Wikipedia:Testosterone_17beta-dehydrogenase_(NADP+)|KEGG_REACTION:R01838		molecular_function											owl:Class	
GO:0042385	biolink:NamedThing	myosin III complex	A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain.	got7fsn_ti														cellular_component											owl:Class	
GO:0050733	biolink:NamedThing	RS domain binding	Binding to an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing.	got7fsn_ti														molecular_function											owl:Class	
GO:0003111	biolink:NamedThing	positive regulation of heart rate by circulating epinephrine	The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction.	got7fsn_ti	positive regulation of heart rate by circulating adrenaline													biological_process											owl:Class	
GO:0047208	biolink:NamedThing	o-dihydroxycoumarin 7-O-glucosyltransferase activity	Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H(+) + UDP.	got7fsn_ti	UDP-glucose:o-dihydroxycoumarin glucosyltransferase activity|UDPglucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase activity|UDP-glucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity											EC:2.4.1.104|MetaCyc:2.4.1.104-RXN|KEGG_REACTION:R03548|RHEA:14325		molecular_function											owl:Class	
GO:0051559	biolink:NamedThing	phlobaphene biosynthetic process	The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.	got7fsn_ti														biological_process											owl:Class	
GO:1903524	biolink:NamedThing	positive regulation of blood circulation	Any process that activates or increases the frequency, rate or extent of blood circulation.	got7fsn_ti	up-regulation of hemolymph circulation|up regulation of hemolymph circulation|activation of blood circulation|up-regulation of blood circulation|upregulation of hemolymph circulation|positive regulation of hemolymph circulation|up regulation of blood circulation|activation of hemolymph circulation|upregulation of blood circulation						mr	2014-10-06T18:39:13Z						biological_process											owl:Class	
GO:0033078	biolink:NamedThing	extrathymic T cell differentiation	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.	got7fsn_ti	extrathymic T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0080103	biolink:NamedThing	4-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate.	got7fsn_ti							dhl	2009-04-23T04:27:45Z						molecular_function											owl:Class	
GO:0007077	biolink:NamedThing	mitotic nuclear membrane disassembly	The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.	got7fsn_ti	local NEB|mitotic nuclear envelope catabolism|mitotic nuclear envelope breakdown|mitotic nuclear envelope degradation|nuclear envelope breakdown|mitotic nuclear envelope disassembly|NEB													biological_process											owl:Class	
GO:0102827	biolink:NamedThing	galactosylononitol-raffinose galactosyltransferase activity	Catalysis of the reaction: raffinose + D-galactosylononitol = stachyose + 1D-4-O-methyl-myo-inositol.	got7fsn_ti												MetaCyc:RXN-8282		molecular_function											owl:Class	
GO:0022028	biolink:NamedThing	tangential migration from the subventricular zone to the olfactory bulb	The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.	got7fsn_ti	rostral migratory stream migration													biological_process											owl:Class	
GO:0001512	biolink:NamedThing	dihydronicotinamide riboside quinone reductase activity	Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.	got7fsn_ti	QR2 activity|N-ribosyldihydronicotinamide dehydrogenase (quinone) activity|NQO(2) activity|NQO2|quinone reductase 2 activity|NRH:quinone oxidoreductase 2 activity|ribosyldihydronicotinamide dehydrogenase (quinone) activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.10.99.2.							MetaCyc:1.10.99.2-RXN|EC:1.10.5.1|RHEA:12364|Reactome:R-HSA-8936519		molecular_function											owl:Class	
GO:0003883	biolink:NamedThing	CTP synthase activity	Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP.	got7fsn_ti	UTP:ammonia ligase (ADP-forming)|cytidine 5'-triphosphate synthetase activity|UTP--ammonia ligase activity|CTP synthetase activity|uridine triphosphate aminase activity|cytidine triphosphate synthetase activity											EC:6.3.4.2|Reactome:R-HSA-73647|RHEA:16597|Reactome:R-HSA-504054|MetaCyc:CTPSYN-RXN		molecular_function											owl:Class	
GO:0016929	biolink:NamedThing	SUMO-specific protease activity	Catalysis of the hydrolysis of peptide or isopeptide bonds within SUMO, or between the SUMO and a larger protein to which it has been conjugated.	got7fsn_ti	ULP|SUSP				This term should not be used for direct manual annotation because the supporting experiments should always distinguish whether the activity is part of maturation or SUMO removal.									molecular_function											owl:Class	
GO:0060799	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate.	got7fsn_ti	transforming growth factor beta receptor signalling pathway involved in endodermal cell fate specification						dph	2009-08-06T11:24:01Z						biological_process											owl:Class	
GO:0008695	biolink:NamedThing	3-phenylpropionate dioxygenase activity	Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol.	got7fsn_ti	HcaA1A2CD|3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating) activity|3-phenylpropanoate dioxygenase activity|Hca dioxygenase activity											UM-BBD_enzymeID:e0307|EC:1.14.12.19|MetaCyc:HCAMULTI-RXN|RHEA:20357		molecular_function											owl:Class	
GO:0048047	biolink:NamedThing	mating behavior, sex discrimination	The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner.	got7fsn_ti	mating behaviour, sex discrimination													biological_process											owl:Class	
GO:0097725	biolink:NamedThing	histone H3-K79 dimethylation	The modification of histone H3 by addition of two methyl groups to lysine at position 79 of the histone.	got7fsn_ti	histone H3 K79 dimethylation|histone lysine H3 K79 dimethylation						pr	2016-09-15T12:41:13Z						biological_process											owl:Class	
GO:0034729	biolink:NamedThing	histone H3-K79 methylation	The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.	got7fsn_ti	histone lysine H3 K79 methylation|histone H3K79me|histone H3 K79 methylation													biological_process											owl:Class	
GO:0046659	biolink:NamedThing	digestive hormone activity	The action characteristic of a hormone that takes part in the digestion process.	got7fsn_ti	secretin													molecular_function											owl:Class	
GO:0036133	biolink:NamedThing	11-hydroxythromboxane B2 dehydrogenase activity	Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.	got7fsn_ti	NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity				Note that the KEGG_REACTION:R05060 reaction does not stipulate the acceptor group, and is therefore slightly more general than the activity described by GO:0036133.		bf	2012-03-05T11:05:09Z				RHEA:52312|Reactome:R-HSA-2161732|KEGG_REACTION:R05060		molecular_function											owl:Class	
GO:0045342	biolink:NamedThing	MHC class II biosynthetic process	The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II.	got7fsn_ti	MHC class II anabolism|MHC class II biosynthesis|MHC class II formation|major histocompatibility complex class II biosynthesis|major histocompatibility complex class II biosynthetic process|MHC class II synthesis													biological_process											owl:Class	
GO:0072529	biolink:NamedThing	pyrimidine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.	got7fsn_ti	pyrimidine-containing compound catabolism|pyrimidine-containing compound breakdown|pyrimidine and derivative catabolic process|pyrimidine-containing compound degradation						mah	2011-01-04T03:27:51Z						biological_process											owl:Class	
GO:0047739	biolink:NamedThing	cephalosporin-C deacetylase activity	Catalysis of the reaction: cephalosporin C + H(2)O = acetate + deacetylcephalosporin C + H(+).	got7fsn_ti	cephalosporin acetylesterase activity|cephalosporin C acetylesterase activity|cephalosporin C acetylase activity|cephalosporin-C acetylhydrolase activity|cephalosporin C deacetylase activity|cephalosporin C acetyl-esterase activity|cephalosporin C acetyl-hydrolase activity											MetaCyc:CEPHALOSPORIN-C-DEACETYLASE-RXN|RHEA:22596|KEGG_REACTION:R03062|EC:3.1.1.41		molecular_function											owl:Class	
GO:0033529	biolink:NamedThing	raffinose biosynthetic process	The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	raffinose synthesis|raffinose anabolism|raffinose biosynthesis|raffinose formation													biological_process											owl:Class	
GO:0033978	biolink:NamedThing	phosphonopyruvate hydrolase activity	Catalysis of the reaction: 3-phosphonopyruvate + H(2)O = phosphate + pyruvate.	got7fsn_ti	PPH											MetaCyc:3.11.1.3-RXN|EC:3.11.1.3|RHEA:16673|KEGG_REACTION:R08200		molecular_function											owl:Class	
GO:0004399	biolink:NamedThing	histidinol dehydrogenase activity	Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+.	got7fsn_ti												RHEA:20641|MetaCyc:HISTALDEHYD-RXN|EC:1.1.1.23|MetaCyc:HISTOLDEHYD-RXN		molecular_function											owl:Class	
GO:0033419	biolink:NamedThing	CUA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CUA codon.	got7fsn_ti	CTA codon-amino acid adaptor activity|leucine tRNA				Note that in the standard genetic code, CTA codes for leucine.									molecular_function											owl:Class	
GO:0048849	biolink:NamedThing	neurohypophysis formation	The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.	got7fsn_ti	posterior pituitary biosynthesis|posterior pituitary gland biosynthesis|neurophysis formation|posterior pituitary gland formation|neurophysis biosynthesis|posterior pituitary formation													biological_process											owl:Class	
GO:0033775	biolink:NamedThing	deoxysarpagine hydroxylase activity	Catalysis of the reaction: 10-deoxysarpagine + H(+) + NADPH + O(2) = H(2)O + NADP(+) + sarpagine.	got7fsn_ti	DOSH|10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating) activity											KEGG_REACTION:R05828|MetaCyc:1.14.13.91-RXN|EC:1.14.14.136|RHEA:14237		molecular_function											owl:Class	
GO:0061698	biolink:NamedThing	protein deglutarylation	The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein.	got7fsn_ti							dph	2015-05-07T11:02:31Z						biological_process											owl:Class	
GO:0055036	biolink:NamedThing	virion membrane	The lipid bilayer surrounding a virion.	got7fsn_ti														cellular_component											owl:Class	
GO:0018150	biolink:NamedThing	peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine	The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link.	got7fsn_ti												RESID:AA0250		biological_process											owl:Class	
GO:0102381	biolink:NamedThing	stevioside glucosyltransferase activity (rebaudioside A forming)	Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = rebaudioside A + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13517		molecular_function											owl:Class	
GO:0045520	biolink:NamedThing	interleukin-24 receptor binding	Binding to an interleukin-24 receptor.	got7fsn_ti	IL-24|interleukin-24 receptor ligand													molecular_function											owl:Class	
GO:0033366	biolink:NamedThing	protein localization to secretory granule	A process in which a protein is transported to, or maintained in, a location within a secretory granule.	got7fsn_ti	protein localization in secretory granule|protein localisation in secretory granule													biological_process											owl:Class	
GO:0018809	biolink:NamedThing	E-phenylitaconyl-CoA hydratase activity	Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0331		molecular_function											owl:Class	
GO:0030037	biolink:NamedThing	actin filament reorganization involved in cell cycle	The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs.	got7fsn_ti	actin filament reorganization during cell cycle|actin filament reorganisation involved in cell cycle													biological_process											owl:Class	
GO:0097681	biolink:NamedThing	double-strand break repair via alternative nonhomologous end joining	An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment.	got7fsn_ti	double-strand break repair via microhomology-mediated end joining|A-NHEJ|alt-NHEJ|MMEJ						pr	2014-12-17T15:17:45Z						biological_process											owl:Class	
GO:0102081	biolink:NamedThing	homotaurine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: homotaurine + 2-oxoglutarate(2-) <=> 3-sulfopropanal + L-glutamate(1-).	got7fsn_ti												MetaCyc:RXN-10822		molecular_function											owl:Class	
GO:0102915	biolink:NamedThing	piperitol synthase activity	Catalysis of the reaction: H+ + (+)-pinoresinol + NADPH + O2 <=> (+)-piperitol + NADP + 2 H2O.	got7fsn_ti												MetaCyc:RXN-8695		molecular_function											owl:Class	
GO:0047536	biolink:NamedThing	2-aminoadipate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.	got7fsn_ti	glutamic-ketoadipic transaminase activity|L-2-aminoadipate:2-oxoglutarate aminotransferase activity|alpha-aminoadipate aminotransferase activity|2-aminoadipate aminotransferase activity|glutamate-alpha-ketoadipate transaminase activity|2-aminoadipic aminotransferase activity											Reactome:R-HSA-508561|KEGG_REACTION:R01939|EC:2.6.1.39|Reactome:R-HSA-70952|MetaCyc:2-AMINOADIPATE-AMINOTRANSFERASE-RXN|RHEA:12601		molecular_function											owl:Class	
GO:0090736	biolink:NamedThing	MATH domain binding	Binding to a meprin and TRAF homology (MATH) domain.	got7fsn_ti							tb	2017-02-06T17:08:28Z						molecular_function											owl:Class	
GO:0047167	biolink:NamedThing	1-alkyl-2-acetylglycerol O-acyltransferase activity	Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.	got7fsn_ti	1-hexadecyl-2-acetylglycerol acyltransferase activity|acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase activity											MetaCyc:2.3.1.125-RXN|RHEA:21996|EC:2.3.1.125		molecular_function											owl:Class	
GO:0140569	biolink:NamedThing	extraction of mislocalized protein from ER membrane	The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20237					pg	2020-12-15T07:36:46Z						biological_process											owl:Class	
GO:0106344	biolink:NamedThing	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP	Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H(+) + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase].	got7fsn_ti	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP	https://github.com/geneontology/go-ontology/issues/20274					hjd	2020-12-04T14:48:37Z				RHEA:65756		molecular_function											owl:Class	
GO:0004123	biolink:NamedThing	cystathionine gamma-lyase activity	Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.	got7fsn_ti	gamma-cystathionase activity|L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)|homoserine deaminase activity|L-cystathionine cysteine-lyase (deaminating)|homoserine deaminase-cystathionase activity|homoserine dehydratase activity										GO:0016225	EC:4.4.1.1|MetaCyc:CYSTAGLY-RXN|Reactome:R-HSA-1614583|RHEA:14005|KEGG_REACTION:R01001		molecular_function											owl:Class	
GO:0042791	biolink:NamedThing	5S class rRNA transcription by RNA polymerase III	The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter.	got7fsn_ti	5S rRNA transcription|5S class rRNA transcription from RNA polymerase III type 1 promoter													biological_process											owl:Class	
GO:0031291	biolink:NamedThing	Ran protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state.	got7fsn_ti														biological_process											owl:Class	
GO:0044824	biolink:NamedThing	retroviral 3' processing activity	The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls.	got7fsn_ti	3'-processing activity|3' processing reaction				This reaction may serve to remove heterogeneous extra bases from the viral DNA end, and to stabilize the integrase-DNA complex. The chemistry of cleavage is a simple hydrolysis by single-step transesterification.		jl	2014-02-04T14:51:24Z						molecular_function											owl:Class	
GO:0035211	biolink:NamedThing	spermathecum morphogenesis	The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.	got7fsn_ti					See also the fly_anatomy.ontology term 'spermathecum ; FBbt:00004921'.									biological_process											owl:Class	
GO:0044353	biolink:NamedThing	micropinosome	A membrane-bounded, uncoated intracellular vesicle formed by the process of micropinocytosis.	got7fsn_ti							jl	2011-08-11T10:51:27Z						cellular_component											owl:Class	
GO:0061677	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate <=> pyruvate + D-glyceraldehyde.	got7fsn_ti	KDG aldolase activity|2-keto-3-deoxygluconate aldolase activity						dph	2015-01-15T13:46:25Z			GO:0043725	EC:4.1.2.51|RHEA:35583|MetaCyc:DHDOGALDOL-RXN|MetaCyc:4.1.2.51-RXN		molecular_function											owl:Class	
GO:0031703	biolink:NamedThing	type 2 angiotensin receptor binding	Binding to a type 2 angiotensin receptor.	got7fsn_ti	type 2 angiotensin receptor ligand|AT2 receptor binding													molecular_function											owl:Class	
GO:0052719	biolink:NamedThing	apurinic/apyrimidinic endoribonuclease activity	Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends.	got7fsn_ti	apurinic endoribonuclease activity|apyrimidinic endoribonuclease activity|abasic endoribonuclease activity|AP endoribonuclease activity													molecular_function											owl:Class	
GO:0008535	biolink:NamedThing	respiratory chain complex IV assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.	got7fsn_ti	cytochrome c oxidase complex assembly|cytochrome c oxidase biogenesis													biological_process											owl:Class	
GO:1900564	biolink:NamedThing	chanoclavine-I metabolic process	The chemical reactions and pathways involving chanoclavine-I.	got7fsn_ti	chanoclavine-I metabolism						di	2012-05-15T06:30:25Z						biological_process											owl:Class	
GO:0032542	biolink:NamedThing	sulfiredoxin activity	Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.	got7fsn_ti	Srx1|peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase [ATP-hydrolysing; peroxiredoxin-(S-hydroxycysteine)-forming]|sulphiredoxin activity|peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity											RHEA:17545|EC:1.8.98.2|MetaCyc:1.8.98.2-RXN		molecular_function											owl:Class	
GO:0050469	biolink:NamedThing	sabinene-hydrate synthase activity	Catalysis of the reaction: geranyl diphosphate + H(2)O = diphosphate + sabinene hydrate.	got7fsn_ti	geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming)|sabinene hydrate cyclase activity											MetaCyc:4.2.3.11-RXN|RHEA:19565|KEGG_REACTION:R02006|EC:4.2.3.11		molecular_function											owl:Class	
GO:0071979	biolink:NamedThing	cytoskeleton-mediated cell swimming	Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium.	got7fsn_ti	cytoskeleton-mediated swimming motility						mah	2010-10-21T03:02:36Z						biological_process											owl:Class	
GO:0031642	biolink:NamedThing	negative regulation of myelination	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.	got7fsn_ti	inhibition of myelination|down regulation of myelination|downregulation of myelination|down-regulation of myelination													biological_process											owl:Class	
GO:0034536	biolink:NamedThing	2-hydroxy-8-methylchromene-2-carboxylate isomerase activity	Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate.	got7fsn_ti												UM-BBD_reactionID:r0782|EC:5.3.99.-		molecular_function											owl:Class	
GO:0031473	biolink:NamedThing	myosin III binding	Binding to a class III myosin; myosin III is monomeric and has an N terminal kinase domain.	got7fsn_ti														molecular_function											owl:Class	
GO:0032486	biolink:NamedThing	Rap protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.	got7fsn_ti														biological_process											owl:Class	
GO:0110014	biolink:NamedThing	negative regulation of aggregation involved in sorocarp development	Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.	got7fsn_ti							kmv	2017-05-10T12:53:12Z						biological_process											owl:Class	
GO:0019323	biolink:NamedThing	pentose catabolic process	The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.	got7fsn_ti	pentose degradation|pentose catabolism|pentose breakdown													biological_process											owl:Class	
GO:0010489	biolink:NamedThing	UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity	Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose.	got7fsn_ti														molecular_function											owl:Class	
GO:0031545	biolink:NamedThing	peptidyl-proline 4-dioxygenase activity	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.	got7fsn_ti	prolyl 4-hydroxylase|HIF-type prolyl 4-hydroxylase											Reactome:R-HSA-1234173|Reactome:R-HSA-1234181|Reactome:R-HSA-1234179|Reactome:R-HSA-1234165|Reactome:R-HSA-1234166|Reactome:R-HSA-1234177		molecular_function											owl:Class	
GO:0010239	biolink:NamedThing	chloroplast mRNA processing	Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs.	got7fsn_ti														biological_process											owl:Class	
GO:0047843	biolink:NamedThing	dehydrogluconate dehydrogenase activity	Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2).	got7fsn_ti	alpha-ketogluconate dehydrogenase activity|ketogluconate dehydrogenase activity|2-dehydro-D-gluconate:acceptor 2-oxidoreductase activity|2-oxogluconate dehydrogenase activity|2-keto-D-gluconate dehydrogenase activity											KEGG_REACTION:R07153|MetaCyc:DEHYDROGLUCONATE-DEHYDROGENASE-RXN|RHEA:12368|EC:1.1.99.4		molecular_function											owl:Class	
GO:1990311	biolink:NamedThing	type-I cohesin domain binding	Binding to a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain.	got7fsn_ti							tt	2014-03-07T04:47:31Z						molecular_function											owl:Class	
GO:0047551	biolink:NamedThing	2-oxoaldehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+.	got7fsn_ti	2-ketoaldehyde dehydrogenase|2-oxoaldehyde dehydrogenase (NAD+)|NAD-dependent alpha-ketoaldehyde dehydrogenase activity|NAD-linked alpha-ketoaldehyde dehydrogenase activity|alpha-ketoaldehyde dehydrogenase activity|2-oxoaldehyde:NAD+ 2-oxidoreductase activity|methylglyoxal dehydrogenase activity											Wikipedia:2-oxoaldehyde_dehydrogenase_(NAD+)|EC:1.2.1.23|MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NAD+-RXN|RHEA:22276		molecular_function											owl:Class	
GO:0097535	biolink:NamedThing	lymphoid lineage cell migration into thymus	The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process.	got7fsn_ti	lymphoid lineage restricted progenitor cell migration into thymus						pr	2013-11-28T10:48:58Z						biological_process											owl:Class	
GO:2001232	biolink:NamedThing	positive regulation of protein localization to prospore membrane	Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane.	got7fsn_ti	positive regulation of protein localisation to prospore membrane|positive regulation of protein targeting to forespore membrane|positive regulation of protein targeting to FSM|positive regulation of protein targeting to prospore membrane|positive regulation of protein targeting to ascospore-type prospore membrane|positive regulation of protein-prospore membrane targeting						mah	2011-11-21T04:13:36Z						biological_process											owl:Class	
GO:1903078	biolink:NamedThing	positive regulation of protein localization to plasma membrane	Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.	got7fsn_ti	up-regulation of protein targeting to plasma membrane|activation of protein localisation in plasma membrane|up-regulation of protein localization to plasma membrane|activation of protein localization to plasma membrane|up regulation of protein targeting to plasma membrane|positive regulation of establishment of protein localisation in plasma membrane|activation of protein-plasma membrane targeting|upregulation of protein localization to plasma membrane|positive regulation of protein localisation in plasma membrane|positive regulation of protein targeting to plasma membrane|up-regulation of protein localisation in plasma membrane|up-regulation of protein-plasma membrane targeting|up regulation of protein localization to plasma membrane|upregulation of protein localization in plasma membrane|up regulation of protein localization in plasma membrane|upregulation of protein localisation in plasma membrane|up regulation of protein localisation in plasma membrane|up-regulation of protein localization in plasma membrane|positive regulation of protein localization in plasma membrane|positive regulation of protein-plasma membrane targeting|activation of protein localization in plasma membrane|up regulation of protein-plasma membrane targeting|activation of protein targeting to plasma membrane|upregulation of protein targeting to plasma membrane|positive regulation of establishment of protein localization to plasma membrane|upregulation of protein-plasma membrane targeting						tb	2009-07-10T10:34:17Z			GO:0090004|GO:1905965			biological_process											owl:Class	
GO:0035939	biolink:NamedThing	microsatellite binding	Binding to a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem.	got7fsn_ti	variable number tandem repeat binding|microsatellite DNA binding|VNTR binding						bf	2011-07-20T01:26:26Z						molecular_function											owl:Class	
GO:0033810	biolink:NamedThing	anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity	Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin.	got7fsn_ti	Ss5MaT1|malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase activity											RHEA:21988|MetaCyc:2.3.1.172-RXN|EC:2.3.1.172		molecular_function											owl:Class	
GO:0036203	biolink:NamedThing	taxoid 14-beta-hydroxylase activity	Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O.	got7fsn_ti							bf	2012-04-20T02:40:54Z				KEGG_REACTION:R09867|RHEA:31971|EC:1.14.13.146		molecular_function											owl:Class	
GO:0010994	biolink:NamedThing	free ubiquitin chain polymerization	The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein.	got7fsn_ti							tb	2009-06-03T11:41:03Z						biological_process											owl:Class	
GO:0103058	biolink:NamedThing	kaempferol 3-glucoside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-L-rhamnose <=> kaempferol-3-glucoside-7-rhamnoside + UDP.	got7fsn_ti												MetaCyc:RXN1F-443		molecular_function											owl:Class	
GO:1990535	biolink:NamedThing	neuron projection maintenance	The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	got7fsn_ti	axon maintenance|neuron process maintenance|neurite maintenance|neuron protrusion maintenance|axon homeostasis|neuronal cell projection maintenance						kmv	2014-11-13T22:24:05Z						biological_process											owl:Class	
GO:0052678	biolink:NamedThing	levopimaradiene synthase activity	Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate.	got7fsn_ti	ent-copalyl-diphosphate diphosphate-lyase [ent-abieta-8(14),12-diene-forming] activity											MetaCyc:4.2.3.32-RXN|RHEA:25548|EC:4.2.3.32|KEGG_REACTION:R06302		molecular_function											owl:Class	
GO:0015092	biolink:NamedThing	high-affinity ferric iron transmembrane transporter activity	Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity ferric uptake transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/14372												molecular_function											owl:Class	
GO:0021861	biolink:NamedThing	forebrain radial glial cell differentiation	The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti	radial glial cell differentiation in forebrain													biological_process											owl:Class	
GO:0097316	biolink:NamedThing	cellular response to N-acetyl-D-glucosamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.	got7fsn_ti							pr	2012-05-30T04:01:02Z						biological_process											owl:Class	
GO:0018981	biolink:NamedThing	triethanolamine metabolic process	The chemical reactions and pathways involving triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.	got7fsn_ti	triethanolamine metabolism											UM-BBD_pathwayID:tea		biological_process											owl:Class	
GO:0097698	biolink:NamedThing	telomere maintenance via base-excision repair	A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature.	got7fsn_ti							pr	2016-01-07T11:15:39Z						biological_process											owl:Class	
GO:0031168	biolink:NamedThing	ferrichrome metabolic process	The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.	got7fsn_ti	ferrichrome metabolism													biological_process											owl:Class	
GO:0031932	biolink:NamedThing	TORC2 complex	A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.	got7fsn_ti	mTORC2|TORC 2 complex|TORC2|rapamycin and nutrient-insensitive TOR complex|TOR complex 2											Wikipedia:MTORC1		cellular_component											owl:Class	
GO:0008255	biolink:NamedThing	ecdysis-triggering hormone activity	The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system.	got7fsn_ti														molecular_function											owl:Class	
GO:0103063	biolink:NamedThing	trans-keto-C61-meroacyl-AMP ligase activity	Catalysis of the reaction: ATP(4-) + H2O + a trans-keto-C61-meroacyl-[acp] <=> diphosphoric acid + a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN1G-4143		molecular_function											owl:Class	
GO:0042443	biolink:NamedThing	phenylethylamine metabolic process	The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.	got7fsn_ti	phenylethylamine metabolism													biological_process											owl:Class	
GO:0075000	biolink:NamedThing	response to host osmotic environment	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response of symbiont to host osmotic environment													biological_process											owl:Class	
GO:0150092	biolink:NamedThing	regulation of synaptic scaling	A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell.	got7fsn_ti	regulation of homeostatic synaptic scaling|homeostatic synaptic scaling						bc	2018-08-09T16:27:28Z						biological_process											owl:Class	
GO:0042292	biolink:NamedThing	URM1 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti														molecular_function											owl:Class	
GO:0004474	biolink:NamedThing	malate synthase activity	Catalysis of the reaction: acetyl-CoA + glyoxylate + H(2)O = (S)-malate + CoA + H(+).	got7fsn_ti	glyoxylate transacetase activity|acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|malic synthetase activity|malate condensing enzyme activity|glyoxylic transacetase activity|malate synthetase activity|glyoxylate transacetylase activity|malic-condensing enzyme activity|L-malate glyoxylate-lyase (CoA-acetylating) activity				Note that this function was formerly EC:4.1.3.2.							MetaCyc:MALSYN-RXN|RHEA:18181|EC:2.3.3.9|KEGG_REACTION:R00472		molecular_function											owl:Class	
GO:2001309	biolink:NamedThing	gliotoxin catabolic process	The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.	got7fsn_ti	gliotoxin catabolism|gliotoxin breakdown|gliotoxin degradation						pr	2012-03-15T03:42:14Z						biological_process											owl:Class	
GO:0032296	biolink:NamedThing	double-stranded RNA-specific ribonuclease activity	Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.	got7fsn_ti	dsRNA-specific ribonuclease activity|double-stranded RNA-specific RNase activity|dsRNA-specific RNase activity													molecular_function											owl:Class	
GO:0039723	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1.	got7fsn_ti	inhibition of host TBK1 by virus|suppression by virus of host TBK1 activity	https://github.com/geneontology/go-ontology/issues/21970					bf	2014-01-06T12:04:44Z						biological_process											owl:Class	
GO:0102936	biolink:NamedThing	gypsogenate-UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenate = gypsogenate-28-beta-D-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-9013		molecular_function											owl:Class	
GO:0002326	biolink:NamedThing	B cell lineage commitment	The process in which a lymphoid progenitor cell becomes committed to become any type of B cell.	got7fsn_ti	B lymphocyte lineage commitment|B-cell lineage commitment|B-lymphocyte lineage commitment													biological_process											owl:Class	
GO:0004076	biolink:NamedThing	biotin synthase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H(+).	got7fsn_ti	dethiobiotin:sulfur sulfurtransferase activity|biotin synthetase activity											RHEA:22060|EC:2.8.1.6|MetaCyc:2.8.1.6-RXN|KEGG_REACTION:R01078		molecular_function											owl:Class	
GO:0047305	biolink:NamedThing	(R)-3-amino-2-methylpropionate-pyruvate transaminase activity	Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.	got7fsn_ti	beta-aminoisobutyrate--pyruvate transaminase activity|D-3-aminoisobutyrate--pyruvate transaminase activity|(R)-3-amino-2-methylpropanoate transaminase activity|D-beta-aminoisobutyrate:pyruvate aminotransferase activity|(R)-3-amino-2-methylpropionate-pyruvate aminotransferase activity|beta-aminoisobutyrate-pyruvate aminotransferase activity|D-AIBAT activity|(R)-3-amino-2-methylpropanoate aminotransferase activity|D-3-aminoisobutyrate-pyruvate transaminase activity|(R)-3-amino-2-methylpropionate--pyruvate aminotransferase activity|(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase activity|D-3-aminoisobutyrate--pyruvate aminotransferase activity|(R)-3-amino-2-methylpropionate transaminase activity				Note that this function was EC:2.6.1.61.						GO:0047314	Reactome:R-HSA-909780|KEGG_REACTION:R02050|EC:2.6.1.40|MetaCyc:2.6.1.40-RXN|RHEA:18393		molecular_function											owl:Class	
GO:0046480	biolink:NamedThing	galactolipid galactosyltransferase activity	Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol.	got7fsn_ti	GGGT activity|3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase activity|galactolipid-galactolipid galactosyltransferase activity|galactolipid:galactolipid galactosyltransferase activity|digalactosyldiacylglycerol synthase activity|DGDG synthase activity|interlipid galactosyltransferase activity											MetaCyc:RXN-1226|EC:2.4.1.184|RHEA:15921		molecular_function											owl:Class	
GO:0033420	biolink:NamedThing	CUG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CUG codon.	got7fsn_ti	CTG codon-amino acid adaptor activity|leucine tRNA				Note that in the standard genetic code, CTG codes for leucine.									molecular_function											owl:Class	
GO:0060183	biolink:NamedThing	apelin receptor signaling pathway	The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands.	got7fsn_ti	apelin receptor signalling pathway													biological_process											owl:Class	
GO:0070200	biolink:NamedThing	establishment of protein localization to telomere	The directed movement of a protein to a specific location in the telomeric region of a chromosome.	got7fsn_ti	establishment of protein localization to chromosome, telomeric region|establishment of protein localisation to telomere													biological_process											owl:Class	
GO:0046737	biolink:NamedThing	induction of cell-mediated immune response in host by virus	The intentional, virally-encoded stimulation of a cell-mediated host defense response to viral infection.	got7fsn_ti	active induction of cell-mediated immune response in host by virus|active viral induction of cell-mediated immune response in host													biological_process											owl:Class	
GO:0050500	biolink:NamedThing	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity	Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate.	got7fsn_ti	beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity|beta-1,3-galactosyl-N-acetylhexosamine phosphorylase activity|beta-D-galactopyranosyl-(1,3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity											RHEA:20285|EC:2.4.1.211|MetaCyc:2.4.1.211-RXN		molecular_function											owl:Class	
GO:0061768	biolink:NamedThing	magnesium:sodium antiporter activity	Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in).	got7fsn_ti							dph	2016-05-04T14:45:45Z						molecular_function											owl:Class	
GO:0062206	biolink:NamedThing	manoyl oxide synthase activity	Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate.	got7fsn_ti							dph	2020-01-03T14:48:52Z				EC:4.2.3.190|RHEA:54516		molecular_function											owl:Class	
GO:0034277	biolink:NamedThing	ent-cassa-12,15-diene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate.	got7fsn_ti	ent-copalyl-diphosphate diphosphate-lyase (ent-cassa-12,15-diene-forming) activity											MetaCyc:RXN-4881|RHEA:25532|EC:4.2.3.28|KEGG_REACTION:R09119		molecular_function											owl:Class	
GO:0017086	biolink:NamedThing	3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex	A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate.	got7fsn_ti	branched-chain alpha-ketoacid dehydrogenase complex|BCADH										GO:0031212			cellular_component											owl:Class	
GO:0102301	biolink:NamedThing	gamma-linolenate elongase activity	Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-12777		molecular_function											owl:Class	
GO:0052587	biolink:NamedThing	diacetyl reductase ((R)-acetoin forming) activity	Catalysis of the reaction: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH.	got7fsn_ti	(R)-acetoin dehydrogenase activity											KEGG_REACTION:R02855|MetaCyc:RXN-11036|RHEA:22900|EC:1.1.1.303		molecular_function											owl:Class	
GO:0102494	biolink:NamedThing	GA20 2,3-desaturase activity	Catalysis of the reaction: gibberellin A20 + O2 + a reduced electron acceptor <=> gibberellin A5 + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-14317		molecular_function											owl:Class	
GO:0033876	biolink:NamedThing	glycochenodeoxycholate sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+).	got7fsn_ti	BAST|bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity|bile acid:PAPS:sulfotransferase activity|3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase activity											EC:2.8.2.34|KEGG_REACTION:R07289|MetaCyc:2.8.2.34-RXN|RHEA:17689		molecular_function											owl:Class	
GO:0004768	biolink:NamedThing	stearoyl-CoA 9-desaturase activity	Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O.	got7fsn_ti	fatty acid desaturase|stearoyl-CoA desaturase activity|delta(9)-desaturase activity|delta9-desaturase|acyl-CoA desaturase				Note that this function was formerly EC:1.14.99.5.						GO:0043735|GO:0016214	EC:1.14.19.1|Reactome:R-HSA-5690565|RHEA:19721|MetaCyc:1.14.19.1-RXN|Reactome:R-HSA-8847579		molecular_function											owl:Class	
GO:0007546	biolink:NamedThing	somatic processes downstream of sex determination signal	The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways.	got7fsn_ti														biological_process											owl:Class	
GO:0070176	biolink:NamedThing	DRM complex	A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification.	got7fsn_ti	DP/Rb/MuvB													cellular_component											owl:Class	
GO:0102706	biolink:NamedThing	butein:oxygen oxidoreductase activity	Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 = aureusidin 6-O-beta-glucoside + H2O + H+.	got7fsn_ti												RHEA:34203|EC:1.21.3.6|MetaCyc:RXN-6242		molecular_function											owl:Class	
GO:0031013	biolink:NamedThing	troponin I binding	Binding to troponin I, the inhibitory subunit of the troponin complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0008968	biolink:NamedThing	D-sedoheptulose 7-phosphate isomerase activity	Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate.	got7fsn_ti	phosphoheptose isomerase activity											RHEA:27489|MetaCyc:RXN0-4301		molecular_function											owl:Class	
GO:0016251	biolink:NamedThing	RNA polymerase II general transcription initiation factor activity	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP). In most species, RNA polymerase II transcribes all messenger RNAs (mRNAs), most untranslated regulatory RNAs, the majority of the snoRNAs, four of the five snRNAs (U1, U2, U4, and U5), and other small noncoding RNAs. For some small RNAs there is variability between species as to whether it is transcribed by RNA polymerase II or RNA polymerase III. However there are also rare exceptions, such as Trypanosoma brucei, where RNA polymerase I transcribes certain mRNAs in addition to its normal role in rRNA transcription.	got7fsn_ti	general RNA polymerase II transcription factor activity|sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly|transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly|GTF2 activity|basal RNA polymerase II transcription factor activity	https://github.com/geneontology/go-ontology/issues/20253			General transcription factors assemble with the RNA polymerase at promoter DNA to form the pre-initiation complex (PIC), bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present in all promoters to initiate transcription. The distinction between general transcription factors and DNA-binding transcription factors is that the latter modulate the selection of which genes are expressed under specific conditions, while general transcription factors belong to the constitutive machinery required for transcription to occur.						GO:0000983|GO:0001075|GO:0003703			molecular_function											owl:Class	
GO:0102909	biolink:NamedThing	alpha-ketoglutarate reductase activity (NADH-dependent)	Catalysis of the reaction: NAD + 2-hydroxyglutarate = H+ + 2-oxoglutarate + NADH.	got7fsn_ti												MetaCyc:RXN-8645		molecular_function											owl:Class	
GO:0071696	biolink:NamedThing	ectodermal placode development	The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.	got7fsn_ti							mah	2010-03-02T11:48:01Z						biological_process											owl:Class	
GO:0035380	biolink:NamedThing	very long-chain-3-hydroxyacyl-CoA dehydrogenase activity	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	got7fsn_ti	very-long-chain-3-hydroxyacyl-CoA dehydrogenase activity						bf	2010-03-18T11:23:05Z						molecular_function											owl:Class	
GO:0033424	biolink:NamedThing	CCG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CCG codon.	got7fsn_ti	proline tRNA				Note that in the standard genetic code, CCG codes for proline.									molecular_function											owl:Class	
GO:0042271	biolink:NamedThing	susceptibility to natural killer cell mediated cytotoxicity	The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.	got7fsn_ti	susceptibility to natural killer cell mediated cell killing|susceptibility to natural killer cell mediated cytolysis|susceptibility to natural killer cell mediated cell death|susceptibility to NK cell mediated cell killing|susceptibility to NK cell mediated cytotoxicity|susceptibility to NK cell mediated cell death|susceptibility to NK cell mediated cytolysis				Note that this term is intended for cell-surface molecules on a target cell which interact with activating receptors on a natural killer cell to promote natural killer cell mediated cytotoxicity.									biological_process											owl:Class	
GO:0045954	biolink:NamedThing	positive regulation of natural killer cell mediated cytotoxicity	Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.	got7fsn_ti	positive regulation of NK cell mediated cytolysis|up-regulation of natural killer cell mediated cytotoxicity|activation of natural killer cell mediated cytotoxicity|upregulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytolysis|up regulation of natural killer cell mediated cytotoxicity|stimulation of natural killer cell mediated cytotoxicity|positive regulation of NK cell mediated cell killing|positive regulation of natural killer cell mediated cell death|positive regulation of natural killer cell mediated cell killing|positive regulation of NK cell mediated cell death|positive regulation of NK cell mediated cytotoxicity													biological_process											owl:Class	
GO:0006435	biolink:NamedThing	threonyl-tRNA aminoacylation	The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0033449	biolink:NamedThing	GUU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GUU codon.	got7fsn_ti	GTT codon-amino acid adaptor activity|valine tRNA				Note that in the standard genetic code, GTT codes for valine.									molecular_function											owl:Class	
GO:1990030	biolink:NamedThing	pericellular basket	Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name.	got7fsn_ti	peri cellular basket|peri-cellular basket						pr	2013-02-07T12:53:54Z				NIF_Subcellular:sao413722576		cellular_component											owl:Class	
GO:0044843	biolink:NamedThing	cell cycle G1/S phase transition	The cell cycle process by which a cell in G1 phase commits to S phase.	got7fsn_ti							jl	2014-03-25T16:33:47Z						biological_process											owl:Class	
GO:0086091	biolink:NamedThing	regulation of heart rate by cardiac conduction	A cardiac conduction process that modulates the frequency or rate of heart contraction.	got7fsn_ti							dph	2011-11-29T01:04:19Z						biological_process											owl:Class	
GO:0097695	biolink:NamedThing	establishment of protein-containing complex localization to telomere	The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome.	got7fsn_ti	establishment of macromolecular complex localization to telomere|establishment of macromolecular complex localisation to telomere						pr	2015-12-22T09:38:13Z						biological_process											owl:Class	
GO:0004773	biolink:NamedThing	steryl-sulfatase activity	Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate.	got7fsn_ti	arylsulfatase C activity|phenolic steroid sulfatase activity|steroid sulfate sulfohydrolase activity|dehydroepiandrosterone sulfate sulfatase activity|3-beta-hydroxysteroid sulfate sulfatase activity|steryl-sulfate sulfohydrolase activity|sterol sulfatase activity|steroid 3-sulfatase activity|pregnenolone sulfatase activity|steroid sulfatase activity|dehydroepiandrosterone sulfatase activity|steryl-sulphatase activity											EC:3.1.6.2|Reactome:R-HSA-1606839|MetaCyc:STERYL-SULFATASE-RXN|RHEA:19873		molecular_function											owl:Class	
GO:0070846	biolink:NamedThing	Hsp90 deacetylation	The modification of an Hsp90 protein by removal of acetyl groups.	got7fsn_ti							mah	2009-07-31T12:58:47Z						biological_process											owl:Class	
GO:0010418	biolink:NamedThing	rhamnogalacturonan II backbone metabolic process	The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues.	got7fsn_ti	rhamnogalacturonan II backbone metabolism													biological_process											owl:Class	
GO:0010396	biolink:NamedThing	rhamnogalacturonan II metabolic process	The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.	got7fsn_ti	rhamnogalacturonan II metabolism													biological_process											owl:Class	
GO:0047697	biolink:NamedThing	beta-alanopine dehydrogenase activity	Catalysis of the reaction: (R)-beta-alanopine + H(2)O + NAD(+) = beta-alanine + H(+) + NADH + pyruvate.	got7fsn_ti	N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming)|b-alanopine dehydrogenase activity											RHEA:21684|EC:1.5.1.26|KEGG_REACTION:R00906|MetaCyc:BETA-ALANOPINE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0016430	biolink:NamedThing	tRNA (adenine-N6-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine.	got7fsn_ti	S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase activity											MetaCyc:TRNA-ADENINE-N6--METHYLTRANSFERASE-RXN|EC:2.1.1.55|RHEA:16785		molecular_function											owl:Class	
GO:0120148	biolink:NamedThing	host cell centrosome	A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.	got7fsn_ti	host centrosome						krc	2018-04-13T15:22:54Z						cellular_component											owl:Class	
GO:0106162	biolink:NamedThing	mRNA N-acetyltransferase activity	Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H(+) + phosphate.	got7fsn_ti							hjd	2018-12-18T19:19:06Z				RHEA:58480		molecular_function											owl:Class	
GO:0018467	biolink:NamedThing	formaldehyde dehydrogenase activity	Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH.	got7fsn_ti	glutathione-independent formaldehyde dehydrogenase activity|formaldehyde:NAD+ oxidoreductase activity											UM-BBD_reactionID:r0240|MetaCyc:FORMALDEHYDE-DEHYDROGENASE-RXN|RHEA:16425|EC:1.2.1.46|KEGG_REACTION:R00604		molecular_function											owl:Class	
GO:0140208	biolink:NamedThing	apoptotic process in response to mitochondrial fragmentation	Any apoptotic process that occurs as a result of mitochondrial fragmentation.	got7fsn_ti	apoptosis in response to mitochondrial fragmentation						pg	2018-03-08T16:54:17Z						biological_process											owl:Class	
GO:0033441	biolink:NamedThing	AAU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AAU codon.	got7fsn_ti	AAT codon-amino acid adaptor activity|asparagine tRNA				Note that in the standard genetic code, AAT codes for asparagine.									molecular_function											owl:Class	
GO:0106256	biolink:NamedThing	hydroperoxy icosatetraenoate dehydratase activity	A hydroperoxy icosatetraenoate <=> an oxoicosatetraenoate + H(2)O.	got7fsn_ti							hjd	2020-03-20T14:40:16Z				RHEA:55556|EC:4.2.1.152		molecular_function											owl:Class	
GO:0016556	biolink:NamedThing	mRNA modification	The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti	mRNA editing				The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.						GO:0006381			biological_process											owl:Class	
GO:0010211	biolink:NamedThing	IAA-Leu conjugate hydrolase activity	Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine.	got7fsn_ti												MetaCyc:RXN-2982		molecular_function											owl:Class	
GO:0043617	biolink:NamedThing	cellular response to sucrose starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose.	got7fsn_ti														biological_process											owl:Class	
GO:0106359	biolink:NamedThing	2-hydroxyacyl-CoA lyase activity	Catalysis of the reaction: A 2-hydroxyacyl-CoA = formyl-CoA + a propanol.	got7fsn_ti							hjd	2021-02-03T16:12:00Z						molecular_function											owl:Class	
GO:0102564	biolink:NamedThing	aurachin C epoxide hydrolase/isomerase activity	Catalysis of the reaction: aurachin C epoxide + H+ + NAD(P)H <=> aurachin B + H2O + NAD(P).	got7fsn_ti												MetaCyc:RXN-15030|RHEA:48728		molecular_function											owl:Class	
GO:0045879	biolink:NamedThing	negative regulation of smoothened signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.	got7fsn_ti	negative regulation of smoothened by patched|negative regulation of hedgehog signaling pathway|downregulation of smoothened signaling pathway|negative regulation of smoothened receptor activity by patched|negative regulation of hh signaling pathway|negative regulation of smoothened signalling pathway|down-regulation of smoothened signaling pathway|negative regulation of smoothened activity|down regulation of smoothened signaling pathway|inhibition of smoothened signaling pathway										GO:0045877			biological_process											owl:Class	
GO:0010967	biolink:NamedThing	regulation of polyamine biosynthetic process	Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.	got7fsn_ti							tb	2009-05-20T11:45:37Z						biological_process											owl:Class	
GO:0043910	biolink:NamedThing	ATP:coenzyme F420 adenylyltransferase activity	Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate.	got7fsn_ti	coenzyme F390-A synthetase activity|ATP:coenzyme F420 adenyltransferase activity											MetaCyc:RXN-9385		molecular_function											owl:Class	
GO:0004122	biolink:NamedThing	cystathionine beta-synthase activity	Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.	got7fsn_ti	serine sulfhydrylase activity|L-serine hydro-lyase (adding homocysteine)|L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|beta-thionase activity|methylcysteine synthase activity|serine sulfhydrase activity											RHEA:10112|MetaCyc:CYSTATHIONINE-BETA-SYNTHASE-RXN|EC:4.2.1.22|Reactome:R-HSA-1614524		molecular_function											owl:Class	
GO:0008267	biolink:NamedThing	poly-glutamine tract binding	Binding to a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:1902404	biolink:NamedThing	mitotic actomyosin contractile ring contraction	Any actomyosin contractile ring contraction that is involved in mitotic cell cycle.	got7fsn_ti	cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|mitotic actomyosin contractile ring constriction	https://github.com/geneontology/go-ontology/issues/21855					jl	2013-09-12T12:27:57Z						biological_process											owl:Class	
GO:0018486	biolink:NamedThing	2-butanone oxidase activity	Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate.	got7fsn_ti												UM-BBD_reactionID:r0169		molecular_function											owl:Class	
GO:0102756	biolink:NamedThing	very-long-chain 3-ketoacyl-CoA synthase activity	Catalysis of the reaction: malonyl-CoA + a very-long-chain 2,3,4-saturated fatty acyl CoA = carbon dioxide + coenzyme A + a very-long-chain oxoacyl-CoA.	got7fsn_ti												MetaCyc:RXN-7697|RHEA:32727|EC:2.3.1.199		molecular_function											owl:Class	
GO:0046216	biolink:NamedThing	indole phytoalexin catabolic process	The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response.	got7fsn_ti	indole phytoalexin catabolism|indole phytoalexin breakdown|indole phytoalexin degradation													biological_process											owl:Class	
GO:0032976	biolink:NamedThing	release of matrix enzymes from mitochondria	The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.	got7fsn_ti	release of aspartate aminotransferase from mitochondria|mAST release from mitochondria				Annotation to this term should be done with caution, particularly if the mechanism is not well clarified.									biological_process											owl:Class	
GO:2001108	biolink:NamedThing	positive regulation of Rho guanyl-nucleotide exchange factor activity	Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.	got7fsn_ti	positive regulation of RhoGEF|positive regulation of Rho guanine nucleotide exchange factor						yaf	2011-09-23T10:13:16Z						biological_process											owl:Class	
GO:1905099	biolink:NamedThing	positive regulation of guanyl-nucleotide exchange factor activity	Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity.	got7fsn_ti	upregulation of guanyl-nucleotide releasing factor|activation of GDS|upregulation of GEF|up-regulation of guanyl-nucleotide releasing factor|upregulation of guanyl-nucleotide exchange factor activity|activation of guanyl-nucleotide releasing factor|activation of GDP-dissociation stimulator activity|up-regulation of GDS|up regulation of GEF|positive regulation of guanyl-nucleotide release factor activity|positive regulation of GDS|upregulation of GDP-dissociation stimulator activity|positive regulation of GEF|up regulation of guanyl-nucleotide release factor activity|up-regulation of GEF|activation of guanyl-nucleotide exchange factor activity|upregulation of GDS|up-regulation of GNRP|upregulation of guanyl-nucleotide release factor activity|activation of guanyl-nucleotide release factor activity|positive regulation of GDP-dissociation stimulator activity|up regulation of guanyl-nucleotide exchange factor activity|up-regulation of guanyl-nucleotide exchange factor activity|upregulation of GNRP|activation of GNRP|up-regulation of guanyl-nucleotide release factor activity|up regulation of GNRP|positive regulation of guanyl-nucleotide releasing factor|up regulation of GDS|up-regulation of GDP-dissociation stimulator activity|up regulation of GDP-dissociation stimulator activity|up regulation of guanyl-nucleotide releasing factor|positive regulation of GNRP|activation of GEF	https://github.com/geneontology/go-ontology/issues/18750					sl	2016-03-31T16:09:54Z						biological_process											owl:Class	
GO:1900562	biolink:NamedThing	dehydroaustinol catabolic process	The chemical reactions and pathways resulting in the breakdown of dehydroaustinol.	got7fsn_ti	dehydroaustinol catabolism|dehydroaustinol degradation|dehydroaustinol breakdown						di	2012-05-15T06:27:55Z						biological_process											owl:Class	
GO:0000711	biolink:NamedThing	meiotic DNA repair synthesis	During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template.	got7fsn_ti														biological_process											owl:Class	
GO:0001605	biolink:NamedThing	adrenomedullin receptor activity	Combining with adrenomedullin to initiate a change in cell activity.	got7fsn_ti	G10D receptor													molecular_function											owl:Class	
GO:0050319	biolink:NamedThing	tartrate decarboxylase activity	Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2).	got7fsn_ti	(R,R)-tartrate carboxy-lyase (D-glycerate-forming)|(R,R)-tartrate carboxy-lyase activity											MetaCyc:TARTRATE-DECARBOXYLASE-RXN|KEGG_REACTION:R01751|EC:4.1.1.73|RHEA:13317		molecular_function											owl:Class	
GO:0009242	biolink:NamedThing	colanic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.	got7fsn_ti	colanic acid formation|M antigen biosynthetic process|colanic acid synthesis|colanic acid anabolism|colanic acid biosynthesis|M antigen biosynthesis											MetaCyc:COLANSYN-PWY		biological_process											owl:Class	
GO:0120201	biolink:NamedThing	cone photoreceptor disc membrane	Stack of disc membranes located inside a cone photoreceptor outer segment, and containing densely packed molecules of opsin photoreceptor proteins that traverse the lipid bilayer. Cone disc membranes arise as evaginations of the ciliary membrane during the development of the cone outer segment and remain contiguous with the ciliary membrane.	got7fsn_ti							krc	2019-05-07T23:17:43Z						cellular_component											owl:Class	
GO:0002115	biolink:NamedThing	store-operated calcium entry	A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum.	got7fsn_ti	store-operated calcium import|calcium ion import|capacitative calcium entry|SOCE				SOCE is initiated by response to stiumlation of membrane receptors leading to the hydrolysis ofphosphatidylinositol bisphosphate (PIP2), inositol 1,4,5-trisphosphate (IP3) generation, and IP3-mediated calcium ion release from the endoplasmic reticulum.									biological_process											owl:Class	
GO:0048678	biolink:NamedThing	response to axon injury	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0015952	biolink:NamedThing	purine deoxyribonucleotide interconversion	The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide.	got7fsn_ti														biological_process											owl:Class	
GO:0072759	biolink:NamedThing	cellular response to topoisomerase inhibitor	Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.	got7fsn_ti							mah	2012-11-09T11:38:08Z						biological_process											owl:Class	
GO:0072758	biolink:NamedThing	response to topoisomerase inhibitor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.	got7fsn_ti							mah	2012-11-09T11:34:51Z						biological_process											owl:Class	
GO:0046538	biolink:NamedThing	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate.	got7fsn_ti	glycerate phosphomutase (diphosphoglycerate cofactor) activity|PGAM-d													molecular_function											owl:Class	
GO:0046754	biolink:NamedThing	viral exocytosis	The exit of enveloped or unenveloped virion particles from the host cell by exocytosis, without causing cell lysis.	got7fsn_ti														biological_process											owl:Class	
GO:0030654	biolink:NamedThing	beta-lactam antibiotic biosynthetic process	The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.	got7fsn_ti	beta-lactam antibiotic anabolism|beta-lactam antibiotic synthesis|beta-lactam antibiotic biosynthesis|beta-lactam antibiotic formation													biological_process											owl:Class	
GO:0004778	biolink:NamedThing	succinyl-CoA hydrolase activity	Catalysis of the reaction: H(2)O + succinyl-CoA = CoA + H(+) + succinate.	got7fsn_ti	succinyl coenzyme A deacylase activity|succinyl coenzyme A hydrolase activity|succinyl-CoA acylase activity											MetaCyc:SUCCINYL-COA-HYDROLASE-RXN|RHEA:11516|EC:3.1.2.3|KEGG_REACTION:R00407		molecular_function											owl:Class	
GO:0140529	biolink:NamedThing	CMG complex assembly	The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16570					pg	2020-10-12T16:42:17Z						biological_process											owl:Class	
GO:0060312	biolink:NamedThing	regulation of blood vessel remodeling	Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.	got7fsn_ti														biological_process											owl:Class	
GO:0004438	biolink:NamedThing	phosphatidylinositol-3-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.	got7fsn_ti	inositol-1,3-bisphosphate 3-phosphatase activity|inositol-polyphosphate 3-phosphatase activity|phosphatidyl-3-phosphate 3-phosphohydrolase activity|D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase activity|inositol 1,3-bisphosphate phosphatase activity|inositol-1,4,-bisphosphate 3-phosphatase activity|1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase activity				Note that this function includes EC:3.1.3.65.						GO:0016315	Reactome:R-HSA-1675795|Reactome:R-HSA-6809720|Reactome:R-HSA-1676141|MetaCyc:PHOSPHATIDYLINOSITOL-3-PHOSPHATASE-RXN|RHEA:12316|Reactome:R-HSA-6809777|Reactome:R-HSA-1675994|Reactome:R-HSA-6809975|Reactome:R-HSA-6809325|Reactome:R-HSA-1676114|EC:3.1.3.64		molecular_function											owl:Class	
GO:0102890	biolink:NamedThing	naringenin chalcone 4'-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone <=> UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+.	got7fsn_ti												EC:2.4.1.286|RHEA:34291|MetaCyc:RXN-8453		molecular_function											owl:Class	
GO:0031960	biolink:NamedThing	response to corticosteroid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.	got7fsn_ti	response to corticosteroid stimulus													biological_process											owl:Class	
GO:0103026	biolink:NamedThing	fructose-1-phosphatase activity	Catalysis of the reaction: beta-D-fructofuranose 1-phosphate + H2O <=> beta-D-fructofuranose + hydrogenphosphate.	got7fsn_ti												RHEA:35603|MetaCyc:RXN0-5186		molecular_function											owl:Class	
GO:0004965	biolink:NamedThing	G protein-coupled GABA receptor activity	Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G-protein coupled GABA receptor activity|metabotropic GABA receptor|GABA-B receptor activity											Reactome:R-HSA-1013013|Reactome:R-HSA-1013012		molecular_function											owl:Class	
GO:0047173	biolink:NamedThing	phosphatidylcholine-retinol O-acyltransferase activity	Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine.	got7fsn_ti	phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase activity|lecithin--retinol acyltransferase activity|phosphatidylcholine:retinol-[cellular-retinol-binding-protein] O-acyltransferase activity											MetaCyc:2.3.1.135-RXN|RHEA:17469|EC:2.3.1.135|Reactome:R-HSA-975608		molecular_function											owl:Class	
GO:0018954	biolink:NamedThing	pentaerythritol tetranitrate metabolic process	The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator.	got7fsn_ti	pentaerythritol tetranitrate metabolism											UM-BBD_pathwayID:petn		biological_process											owl:Class	
GO:0033637	biolink:NamedThing	modulation by symbiont of host response to cold	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	freezing tolerance													biological_process											owl:Class	
GO:0033636	biolink:NamedThing	modulation by symbiont of host response to temperature stimulus	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host response to thermal stimulus													biological_process											owl:Class	
GO:0070440	biolink:NamedThing	Mad-Max-mSin3B complex	A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.	got7fsn_ti														cellular_component											owl:Class	
GO:0047979	biolink:NamedThing	hexose oxidase activity	Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.	got7fsn_ti	D-hexose:oxygen 1-oxidoreductase activity											EC:1.1.3.5|MetaCyc:HEXOSE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0031153	biolink:NamedThing	slug development involved in sorocarp development	The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development.	got7fsn_ti	standing slug development during sorocarp development|slug development during fruiting body development|pseudoplasmodium formation|migratory slug development during sorocarp development|slug development during sorocarp development|pseudoplasmodium biosynthesis													biological_process											owl:Class	
GO:0051221	biolink:NamedThing	tungsten incorporation into metallo-sulfur cluster	The incorporation of tungsten into a metallo-sulfur cluster.	got7fsn_ti	tungsten incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0106263	biolink:NamedThing	1-acylglycerophosphoserine O-acyltransferase activity	Catalysis of the reaction:a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA.	got7fsn_ti							hjd	2020-05-18T15:12:42Z				RHEA:33191		molecular_function											owl:Class	
GO:0030738	biolink:NamedThing	tyramine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	tyramine methylpherase activity|DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid)|S-adenosyl-L-methionine:tyramine N-methyltransferase activity|S-adenosyl-methionine:tyramine N-methyltransferase activity											MetaCyc:TYRAMINE-N-METHYLTRANSFERASE-RXN|RHEA:14865|EC:2.1.1.27|KEGG_REACTION:R02384		molecular_function											owl:Class	
GO:0051627	biolink:NamedThing	negative regulation of epinephrine uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.	got7fsn_ti	down regulation of epinephrine uptake|negative regulation of epinephrine import|down-regulation of epinephrine uptake|downregulation of epinephrine uptake|negative regulation of adrenaline uptake													biological_process											owl:Class	
GO:0071730	biolink:NamedThing	beak formation	The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.	got7fsn_ti							mah	2010-03-17T03:57:07Z						biological_process											owl:Class	
GO:1990915	biolink:NamedThing	structural constituent of ascospore wall	The action of a molecule that contributes to the structural integrity of an ascospore wall.	got7fsn_ti							al	2015-12-09T19:04:53Z						molecular_function											owl:Class	
GO:0034302	biolink:NamedThing	akinete formation	The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria.	got7fsn_ti														biological_process											owl:Class	
GO:0034909	biolink:NamedThing	6-hydroxypseudooxynicotine dehydrogenase activity	Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine.	got7fsn_ti												UM-BBD_reactionID:r1441|RHEA:34223|EC:1.5.99.14		molecular_function											owl:Class	
GO:0102156	biolink:NamedThing	2,5-DHBA UDP-glucosyltransferase activity	Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose <=> 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-11705		molecular_function											owl:Class	
GO:0042966	biolink:NamedThing	biotin carboxyl carrier protein biosynthetic process	The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase.	got7fsn_ti	BCCP biosynthesis|biotin carboxyl carrier protein formation|biotin carboxyl carrier protein anabolism|biotin carboxyl carrier protein biosynthesis|BCCP biosynthetic process|biotin carboxyl carrier protein synthesis													biological_process											owl:Class	
GO:0102133	biolink:NamedThing	limonene hydroxylase activity	Catalysis of the reaction: (4R)-limonene + O2 + NADH + H+ <=> (4R)-perillyl alcohol + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-11493		molecular_function											owl:Class	
GO:0034362	biolink:NamedThing	low-density lipoprotein particle	A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.	got7fsn_ti	LDL particle|LDL complex|low-density lipoprotein complex													cellular_component											owl:Class	
GO:1900772	biolink:NamedThing	fumitremorgin B biosynthetic process	The chemical reactions and pathways resulting in the formation of fumitremorgin B.	got7fsn_ti	Lanosulin formation|fumitremorgin B biosynthesis|fumitremorgin B formation|Lanosulin biosynthetic process|Lanosulin anabolism|Lanosulin synthesis|fumitremorgin B synthesis|fumitremorgin B anabolism|Lanosulin biosynthesis						di	2012-06-04T09:25:50Z						biological_process											owl:Class	
GO:0031683	biolink:NamedThing	G-protein beta/gamma-subunit complex binding	Binding to a complex of G-protein beta/gamma subunits.	got7fsn_ti														molecular_function											owl:Class	
GO:0036372	biolink:NamedThing	opsin transport	The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.	got7fsn_ti	ciliary transport of opsin						bf	2013-04-23T09:26:29Z						biological_process											owl:Class	
GO:0048173	biolink:NamedThing	positive regulation of short-term neuronal synaptic plasticity	A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.	got7fsn_ti	upregulation of short-term neuronal synaptic plasticity|activation of short-term neuronal synaptic plasticity|up-regulation of short-term neuronal synaptic plasticity|up regulation of short-term neuronal synaptic plasticity|stimulation of short-term neuronal synaptic plasticity				Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.									biological_process											owl:Class	
GO:0005978	biolink:NamedThing	glycogen biosynthetic process	The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.	got7fsn_ti	glycogen biosynthesis|glycogen formation|glycogen anabolism|glycogen synthesis											MetaCyc:GLYCOGENSYNTH-PWY		biological_process											owl:Class	
GO:0103074	biolink:NamedThing	glucose-6-phosphate 3-dehydrogenase activity	Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate.	got7fsn_ti												EC:1.1.1.361|MetaCyc:RXN8J2-136|RHEA:37547		molecular_function											owl:Class	
GO:0031004	biolink:NamedThing	potassium ion-transporting ATPase complex	Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex.	got7fsn_ti	Kdp system complex													cellular_component											owl:Class	
GO:0043214	biolink:NamedThing	ABC-type bacteriocin transporter activity	Enables the transfer of a bacteriocin from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate.	got7fsn_ti	ATPase-coupled bacteriocin transmembrane transporter activity|ABC-type bacteriocin transmembrane transporter activity|bacteriocin ABC transporter													molecular_function											owl:Class	
GO:0043449	biolink:NamedThing	cellular alkene metabolic process	The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells.	got7fsn_ti	alkene metabolism													biological_process											owl:Class	
GO:0050369	biolink:NamedThing	[tyrosine 3-monooxygenase] kinase activity	Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase].	got7fsn_ti	tyrosine 3-monooxygenase kinase (phosphorylating) activity|tyrosine 3-monooxygenase kinase activity|ATP:tyrosine-3-monoxygenase phosphotransferase activity|STK4|pheochromocytoma tyrosine hydroxylase-associated kinase activity											MetaCyc:2.7.11.6-RXN|RHEA:17133|EC:2.7.11.6		molecular_function											owl:Class	
GO:0009421	biolink:NamedThing	bacterial-type flagellum filament cap	The proteinaceous structure at the distal tip of the bacterial-type flagellar filament.	got7fsn_ti	flagellin-based flagellum filament cap|flagellar filament cap													cellular_component											owl:Class	
GO:0010838	biolink:NamedThing	positive regulation of keratinocyte proliferation	Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0034403	biolink:NamedThing	alignment of 3' and 5' splice sites of mRNA	Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur.	got7fsn_ti	alignment of 3' and 5' splice sites of nuclear mRNA													biological_process											owl:Class	
GO:0070049	biolink:NamedThing	endobrevin-SNAP-25-syntaxin-2 complex	A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof).	got7fsn_ti	SNARE complex (Stx2, Snap25, Vamp8)|Stx2-Snap25-Vamp8 complex													cellular_component											owl:Class	
GO:0031836	biolink:NamedThing	neuromedin K receptor binding	Binding to a neuromedin K receptor.	got7fsn_ti	neuromedin K receptor ligand|neurokinin-B receptor binding													molecular_function											owl:Class	
GO:0071522	biolink:NamedThing	ureidoglycine aminohydrolase activity	Catalysis of the reaction: ureidoglycine + H2O = S-ureidoglycolate + NH3.	got7fsn_ti							mah	2010-01-07T01:43:58Z				EC:3.5.3.26|RHEA:25241|MetaCyc:URUR-RXN		molecular_function											owl:Class	
GO:0004470	biolink:NamedThing	malic enzyme activity	Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.	got7fsn_ti	pyruvic-malic carboxylase activity													molecular_function											owl:Class	
GO:0042567	biolink:NamedThing	insulin-like growth factor ternary complex	A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development.	got7fsn_ti	IGF ternary complex													cellular_component											owl:Class	
GO:0031216	biolink:NamedThing	neopullulanase activity	Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose).	got7fsn_ti	pullulan 4-D-glucanohydrolase (panose-forming)|pullulanase II activity											EC:3.2.1.135|MetaCyc:3.2.1.135-RXN		molecular_function											owl:Class	
GO:0039602	biolink:NamedThing	suppression by virus of host transcription initiation from RNA polymerase II promoter	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.	got7fsn_ti	suppression by virus of host DNA-dependent transcription, initiation|inhibition of host transcription initiation by virus						bf	2012-07-05T03:29:34Z			GO:0039601	VZ:904		biological_process											owl:Class	
GO:0071381	biolink:NamedThing	cellular response to prostaglandin F stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.	got7fsn_ti							mah	2009-12-11T03:34:57Z						biological_process											owl:Class	
GO:0061843	biolink:NamedThing	Sertoli cell barrier remodeling	The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle.	got7fsn_ti	restructuring of SCB|blood testis barrier restructuring|restructuring of BTB|SCB remodeling|restructuring of blood-testis barrier|Sertoli cell barrier restructuring													biological_process											owl:Class	
GO:0031731	biolink:NamedThing	CCR6 chemokine receptor binding	Binding to a CCR6 chemokine receptor.	got7fsn_ti	LARC receptor binding|CCR6 chemokine receptor ligand													molecular_function											owl:Class	
GO:0070337	biolink:NamedThing	3'-flap-structured DNA binding	Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0001734	biolink:NamedThing	mRNA (N6-adenosine)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U.	got7fsn_ti												Reactome:R-HSA-72095		molecular_function											owl:Class	
GO:0047557	biolink:NamedThing	3-aci-nitropropanoate oxidase activity	Catalysis of the reaction: 3-aci-nitropropanoate + H(2)O + O(2) = 3-oxopropanoate + H(2)O(2) + nitrite.	got7fsn_ti	3-aci-nitropropanoate:oxygen oxidoreductase activity|propionate-3-nitronate oxidase activity											KEGG_REACTION:R01609|EC:1.7.3.5|MetaCyc:3-ACI-NITROPROPANOATE-OXIDASE-RXN|RHEA:22372		molecular_function											owl:Class	
GO:0015771	biolink:NamedThing	trehalose transport	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0097252	biolink:NamedThing	oligodendrocyte apoptotic process	Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.	got7fsn_ti	oligodendrocyte apoptosis						pr	2012-03-05T10:51:15Z						biological_process											owl:Class	
GO:0004971	biolink:NamedThing	AMPA glutamate receptor activity	An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.	got7fsn_ti	AMPA receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity				Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'.									molecular_function											owl:Class	
GO:1903213	biolink:NamedThing	protein localization to subtelomeric heterochromatin	A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin.	got7fsn_ti	protein localisation to telomeric heterochromatin|protein localisation to subtelomeric heterochromatin|protein localisation in subtelomeric heterochromatin|protein localization in subtelomeric heterochromatin|protein localization to telomeric heterochromatin						mah	2013-07-31T15:04:26Z			GO:1990152			biological_process											owl:Class	
GO:0097265	biolink:NamedThing	5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity	Catalysis of the reaction: 5-HETE + NADP(+) = 5-oxo-ETE + NADPH + H(+).	got7fsn_ti	5(S)-HETE dehydrogenase activity|5-hydroxy-eicosatetraenoic acid dehydrogenase activity|5-HETE dehydrogenase activity						pr	2012-03-09T12:46:02Z				Reactome:R-HSA-2161776		molecular_function											owl:Class	
GO:0043442	biolink:NamedThing	acetoacetic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.	got7fsn_ti	acetoacetic acid breakdown|acetoacetic acid catabolism|acetoacetic acid degradation													biological_process											owl:Class	
GO:0019626	biolink:NamedThing	short-chain fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6.	got7fsn_ti	short-chain fatty acid degradation|short-chain fatty acid catabolism|short-chain fatty acid breakdown											MetaCyc:ACETOACETATE-DEG-PWY		biological_process											owl:Class	
GO:0009879	biolink:NamedThing	determination of radial symmetry	The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis.	got7fsn_ti	determination of radial asymmetry													biological_process											owl:Class	
GO:0070052	biolink:NamedThing	collagen V binding	Binding to a type V collagen trimer.	got7fsn_ti														molecular_function											owl:Class	
GO:0005518	biolink:NamedThing	collagen binding	Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).	got7fsn_ti														molecular_function											owl:Class	
GO:0102258	biolink:NamedThing	1,3-diacylglycerol acylhydrolase activity	Catalysis of the reaction: H2O + a 1,3-diglyceride = a monoglyceride + a fatty acid.	got7fsn_ti												MetaCyc:RXN-12433		molecular_function											owl:Class	
GO:0051409	biolink:NamedThing	response to nitrosative stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.	got7fsn_ti														biological_process											owl:Class	
GO:1990353	biolink:NamedThing	Fused-Smurf ubiquitin ligase complex	A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation.	got7fsn_ti					An example of this is FUSED in Drosophila melanogaster (UniProt symbol P23647) in PMID:21145463 (inferred from direct assay).		bhm	2014-03-27T14:02:09Z						cellular_component											owl:Class	
GO:0047230	biolink:NamedThing	flavonol-3-O-glucoside L-rhamnosyltransferase activity	Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP.	got7fsn_ti	UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase activity|uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase activity|UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase activity											MetaCyc:2.4.1.159-RXN|EC:2.4.1.159|RHEA:22528		molecular_function											owl:Class	
GO:1904269	biolink:NamedThing	cell leading edge cell cortex	The cell cortex of the leading edge of a cell.	got7fsn_ti	peripheral cytoplasm of cell leading edge|cell cortex of leading edge of cell|cell periphery of leading edge of cell|cell cortex of cell leading edge|cell cortex of front of cell|peripheral cytoplasm of front of cell|cell periphery of cell leading edge|peripheral cytoplasm of leading edge of cell|cell periphery of front of cell						kmv	2015-05-28T19:16:03Z						cellular_component											owl:Class	
GO:0048772	biolink:NamedThing	leucophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance.	got7fsn_ti	leucophore cell differentiation													biological_process											owl:Class	
GO:0140380	biolink:NamedThing	psilocybin biosynthetic process	The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product.	got7fsn_ti							pg	2019-11-20T10:03:05Z						biological_process											owl:Class	
GO:0052600	biolink:NamedThing	propane-1,3-diamine oxidase activity	Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+.	got7fsn_ti	trimethylenediamine oxidase activity|propane-1,3-diamine:oxygen oxidoreductase (deaminating) activity|1,3-diaminopropane oxidase activity											KEGG_REACTION:R03139|EC:1.4.3.22|MetaCyc:RXN-6381|RHEA:30895		molecular_function											owl:Class	
GO:0002433	biolink:NamedThing	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.	got7fsn_ti	immune response-regulating cell surface receptor signalling pathway involved in phagocytosis|phagocytosis triggered by activation of immune response cell surface activating receptor													biological_process											owl:Class	
GO:0043993	biolink:NamedThing	histone acetyltransferase activity (H3-K18 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K18 specific)													molecular_function											owl:Class	
GO:0051479	biolink:NamedThing	mannosylglycerate biosynthetic process	The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.	got7fsn_ti	mannosylglycerate formation|mannosylglycerate anabolism|mannosylglycerate synthesis|mannosylglycerate biosynthesis													biological_process											owl:Class	
GO:0031823	biolink:NamedThing	type 1D serotonin receptor binding	Binding to a type 1D serotonin receptor.	got7fsn_ti	type 1D serotonin receptor ligand|5-hydroxytryptamine 1D receptor binding													molecular_function											owl:Class	
GO:0071275	biolink:NamedThing	cellular response to aluminum ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.	got7fsn_ti	cellular response to aluminum|cellular response to aluminium ion						mah	2009-12-10T03:52:20Z						biological_process											owl:Class	
GO:0102729	biolink:NamedThing	6-oxocampestanol hydroxylase activity	Catalysis of the reaction: H+ + 6-oxocampestanol + O2 + NADPH = cathasterone + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-715		molecular_function											owl:Class	
GO:0060510	biolink:NamedThing	type II pneumocyte differentiation	The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.	got7fsn_ti	great alveolar cell differentiation|large alveolar cell differentiation|granular pneumocyte differentiation													biological_process											owl:Class	
GO:0044313	biolink:NamedThing	protein K6-linked deubiquitination	A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein.	got7fsn_ti							jl	2010-06-01T03:10:11Z						biological_process											owl:Class	
GO:0035842	biolink:NamedThing	old cell tip after activation of bipolar cell growth	A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.	got7fsn_ti	post-new end take-off old cell tip|post-NETO old cell tip|post-NETO old cell end						bf	2011-05-06T01:37:23Z						cellular_component											owl:Class	
GO:0035840	biolink:NamedThing	old growing cell tip	A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.	got7fsn_ti	old growing cell end						bf	2011-05-06T01:33:54Z						cellular_component											owl:Class	
GO:0033543	biolink:NamedThing	fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	got7fsn_ti														biological_process											owl:Class	
GO:0010012	biolink:NamedThing	steroid 22-alpha hydroxylase activity	Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O.	got7fsn_ti														molecular_function											owl:Class	
GO:0047888	biolink:NamedThing	fatty acid peroxidase activity	Catalysis of the reaction: 2 H(2)O(2) + H(+) + palmitate = CO(2) + 3 H(2)O + pentadecanal.	got7fsn_ti	fatty-acid peroxidase activity|long chain fatty acid peroxidase activity|hexadecanoate:hydrogen-peroxide oxidoreductase activity											RHEA:23960|KEGG_REACTION:R01703|MetaCyc:FATTY-ACID-PEROXIDASE-RXN|EC:1.11.1.3		molecular_function											owl:Class	
GO:0034730	biolink:NamedThing	SmD-containing SMN-Sm protein complex	An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex.	got7fsn_ti	SMN-containing protein complex													cellular_component											owl:Class	
GO:0071330	biolink:NamedThing	cellular response to trehalose-6-phosphate stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.	got7fsn_ti							mah	2009-12-10T05:32:52Z						biological_process											owl:Class	
GO:0080094	biolink:NamedThing	response to trehalose-6-phosphate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.	got7fsn_ti	response to trehalose-6-phosphate stimulus						dhl	2009-04-22T04:49:13Z						biological_process											owl:Class	
GO:0097008	biolink:NamedThing	(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity	Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone.	got7fsn_ti	(3E)-4,8-dimethylnona-1,3,7-triene synthase activity|DNMT synthase activity						pr	2011-03-17T10:38:01Z				MetaCyc:RXN-8619		molecular_function											owl:Class	
GO:0014893	biolink:NamedThing	response to rest involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.	got7fsn_ti														biological_process											owl:Class	
GO:0042122	biolink:NamedThing	alginic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).	got7fsn_ti	alginic acid catabolism|alginic acid degradation|alginate catabolic process|alginic acid breakdown|alginate catabolism													biological_process											owl:Class	
GO:0042625	biolink:NamedThing	ATPase-coupled ion transmembrane transporter activity	Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate.	got7fsn_ti	ATPase coupled ion transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of ions|ATP-dependent ion transmembrane transporter activity													molecular_function											owl:Class	
GO:0050105	biolink:NamedThing	L-gulonolactone oxidase activity	Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2.	got7fsn_ti	L-gulono-gamma-lactone oxidase activity|L-gulono-1,4-lactone:oxygen 3-oxidoreductase activity|L-gulono-gamma-lactone:O2 oxidoreductase activity|GLO activity|L-gulono-gamma-lactone:oxidoreductase activity											MetaCyc:L-GULONOLACTONE-OXIDASE-RXN|RHEA:32363|EC:1.1.3.8		molecular_function											owl:Class	
GO:0006727	biolink:NamedThing	ommochrome biosynthetic process	The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.	got7fsn_ti	ommochrome anabolism|ommochrome formation|ommochrome synthesis|ommochrome biosynthesis													biological_process											owl:Class	
GO:0061072	biolink:NamedThing	iris morphogenesis	The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.	got7fsn_ti							dph	2010-03-16T10:48:42Z						biological_process											owl:Class	
GO:0034706	biolink:NamedThing	sodium channel complex	An ion channel complex through which sodium ions pass.	got7fsn_ti														cellular_component											owl:Class	
GO:0044644	biolink:NamedThing	envenomation resulting in negative regulation of complement activation, alternative pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism.	got7fsn_ti							jl	2012-07-11T12:35:11Z						biological_process											owl:Class	
GO:0051687	biolink:NamedThing	maintenance of spindle location	Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of spindle localization													biological_process											owl:Class	
GO:1905554	biolink:NamedThing	negative regulation of vessel branching	Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching.	got7fsn_ti	downregulation of patterning of blood vessels|inhibition of patterning of blood vessels|down-regulation of branching involved in blood vessel morphogenesis|negative regulation of branching involved in blood vessel morphogenesis|down-regulation of patterning of blood vessels|down regulation of patterning of blood vessels|inhibition of branching involved in blood vessel morphogenesis|down regulation of branching involved in blood vessel morphogenesis|downregulation of branching involved in blood vessel morphogenesis						nc	2016-10-12T14:19:41Z						biological_process											owl:Class	
GO:0071020	biolink:NamedThing	post-spliceosomal complex	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.	got7fsn_ti	yeast spliceosomal complex A2-3|mammalian spliceosomal complex C2						mah	2009-07-30T12:00:35Z						cellular_component											owl:Class	
GO:0030753	biolink:NamedThing	8-hydroxyfuranocoumarin 8-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin.	got7fsn_ti	furanocoumarin 8-methyltransferase activity|xanthotoxol 8-O-methyltransferase activity|xanthotoxol O-methyltransferase activity|S-adenosyl-L-methionine:xanthotoxol O-methyltransferase activity|furanocoumarin 8-O-methyl-transferase activity|xanthotoxol methyltransferase activity|XMT activity|S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase activity|S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase activity										GO:0030765	KEGG_REACTION:R02982|EC:2.1.1.70		molecular_function											owl:Class	
GO:0019405	biolink:NamedThing	alditol catabolic process	The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.	got7fsn_ti	alditol breakdown|alditol catabolism|alditol degradation													biological_process											owl:Class	
GO:0080054	biolink:NamedThing	low-affinity nitrate transmembrane transporter activity	Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	got7fsn_ti	low affinity nitrate transmembrane transporter activity													molecular_function											owl:Class	
GO:0003681	biolink:NamedThing	bent DNA binding	Binding to DNA in a bent conformation.	got7fsn_ti														molecular_function											owl:Class	
GO:0019229	biolink:NamedThing	regulation of vasoconstriction	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.	got7fsn_ti														biological_process											owl:Class	
GO:0047698	biolink:NamedThing	beta-alanyl-CoA ammonia-lyase activity	Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3.	got7fsn_ti	b-alanyl-CoA ammonia-lyase activity|beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming)|beta-alanyl coenzyme A ammonia-lyase activity											MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN|EC:4.3.1.6|RHEA:12416		molecular_function											owl:Class	
GO:1990146	biolink:NamedThing	protein localization to rhabdomere	A process in which a protein is transported to, or maintained in, a location within a rhabdomere.	got7fsn_ti							sart	2013-07-25T11:24:49Z						biological_process											owl:Class	
GO:0060566	biolink:NamedThing	positive regulation of DNA-templated transcription, termination	Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.	got7fsn_ti	positive regulation of DNA-dependent transcription, termination|positive regulation of termination of DNA-dependent transcription|positive regulation of transcription termination, DNA-dependent						dph	2009-04-29T02:54:50Z						biological_process											owl:Class	
GO:0106389	biolink:NamedThing	ecdysteroid 22-kinase activity	Catalysis of the reaction: an ecdysteroid + ATP = an ecdysteroid 22-phosphate + ADP + H+.	got7fsn_ti							hjd	2021-07-13T14:37:23Z				MetaCyc:RXN-14755		molecular_function											owl:Class	
GO:0036024	biolink:NamedThing	protein C inhibitor-TMPRSS7 complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7.	got7fsn_ti	plasma serine protease inhibitor-TMPRSS7 complex|protein C inhibitor-matriptase-3 complex|PCI-TMPRSS7 complex|protein C inhibitor-transmembrane protease serine 7 complex|serpin A5-TMPRSS7 complex|SERPINA5-TMPRSS7 complex						bf	2011-10-19T01:25:06Z						cellular_component											owl:Class	
GO:0062244	biolink:NamedThing	double membrane vesicle viral factory lumen	The volume surrounded by the inner membrane of a double membrane vesicle viral factory.	got7fsn_ti	lumen of double membrane vesicle viral factory						dph	2020-04-20T20:53:30Z						cellular_component											owl:Class	
GO:0043751	biolink:NamedThing	polyphosphate:AMP phosphotransferase activity	Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP.	got7fsn_ti	PPT|PAP													molecular_function											owl:Class	
GO:0060234	biolink:NamedThing	neuroblast delamination	The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.	got7fsn_ti														biological_process											owl:Class	
GO:0031346	biolink:NamedThing	positive regulation of cell projection organization	Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.	got7fsn_ti	stimulation of cell projection organization|positive regulation of cell projection organization and biogenesis|up regulation of cell projection organization|positive regulation of cell projection organisation|upregulation of cell projection organization|activation of cell projection organization|up-regulation of cell projection organization													biological_process											owl:Class	
GO:0140491	biolink:NamedThing	ubiquitin-like hydrolase activity	An activity that cleaves ubiquitin or ubiquitin-like proteins (ULP) from target proteins.	got7fsn_ti	ubiquitinyl-like hydrolase activity	https://github.com/geneontology/go-ontology/issues/17398					pg	2020-07-01T12:37:19Z						molecular_function											owl:Class	
GO:0047759	biolink:NamedThing	butanal dehydrogenase activity	Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+.	got7fsn_ti	butanal:NAD(P)+ oxidoreductase (CoA-acylating)											EC:1.2.1.57|MetaCyc:BUTANAL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0099128	biolink:NamedThing	mitochondrial iron-sulfur cluster assembly complex	A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine.	got7fsn_ti														cellular_component											owl:Class	
GO:0043509	biolink:NamedThing	activin A complex	A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).	got7fsn_ti					Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and an inhibin alpha subunit. See also the cellular component term 'inhibin complex ; GO:0043511'.						GO:0048181			cellular_component											owl:Class	
GO:0072214	biolink:NamedThing	metanephric cortex development	The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.	got7fsn_ti							mah	2010-03-18T01:29:49Z						biological_process											owl:Class	
GO:0085033	biolink:NamedThing	induction by symbiont of host I-kappaB kinase/NF-kappaB cascade	Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by symbiont of host I-kappaB kinase/NF-kappaB cascade|up-regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of nuclear factor kappa-light-chain-enhancer of activated B cells mediated signal transduction pathway|up regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host NF-kappaB-mediated signal transduction pathway|upregulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|stimulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|induction by symbiont of host I-kappaB kinase/NF-kappaB cascade						jl	2010-07-27T02:47:01Z						biological_process											owl:Class	
GO:0043123	biolink:NamedThing	positive regulation of I-kappaB kinase/NF-kappaB signaling	Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.	got7fsn_ti	up regulation of I-kappaB kinase/NF-kappaB cascade|up-regulation of I-kappaB kinase/NF-kappaB cascade|upregulation of I-kappaB kinase/NF-kappaB cascade|activation of I-kappaB kinase/NF-kappaB cascade|positive regulation of I-kappaB kinase/NF-kappaB cascade|stimulation of I-kappaB kinase/NF-kappaB cascade													biological_process											owl:Class	
GO:0033565	biolink:NamedThing	ESCRT-0 complex	A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.	got7fsn_ti	Hrs/STAM complex|Vps27p-Hse1p complex													cellular_component											owl:Class	
GO:0046568	biolink:NamedThing	3-methylbutanol:NAD(P) oxidoreductase activity	Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde.	got7fsn_ti	3-methylbutanal reductase [NAD(P)] activity|3-methylbutyraldehyde reductase activity|isoamyl alcohol oxidase activity											EC:1.1.1.265|MetaCyc:1.1.1.265-RXN		molecular_function											owl:Class	
GO:0003827	biolink:NamedThing	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H(+) + UDP.	got7fsn_ti	GNTI activity|N-acetylglucosaminyltransferase I activity|UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I activity|UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I activity|alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:3-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity|GnTI|uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity											EC:2.4.1.101|RHEA:11456|MetaCyc:2.4.1.101-RXN|Reactome:R-HSA-964768|KEGG_REACTION:R05983		molecular_function											owl:Class	
GO:0102150	biolink:NamedThing	3-oxo-myristoyl-CoA hydrolase activity	Catalysis of the reaction: 3-oxotetradecanoyl-CoA + H2O <=> 3-oxo-myristate + coenzyme A + H+.	got7fsn_ti												MetaCyc:RXN-11668		molecular_function											owl:Class	
GO:0071292	biolink:NamedThing	cellular response to silver ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.	got7fsn_ti							mah	2009-12-10T04:16:30Z						biological_process											owl:Class	
GO:0010272	biolink:NamedThing	response to silver ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0102335	biolink:NamedThing	N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine <=> N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13274|RHEA:34511|EC:2.4.1.290		molecular_function											owl:Class	
GO:0019827	biolink:NamedThing	stem cell population maintenance	The process by which an organism or tissue maintains a population of stem cells of a single type.  This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.	got7fsn_ti	maintenance of pluripotency													biological_process											owl:Class	
GO:0090175	biolink:NamedThing	regulation of establishment of planar polarity	Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.	got7fsn_ti							tb	2009-12-14T10:29:41Z						biological_process											owl:Class	
GO:0030199	biolink:NamedThing	collagen fibril organization	Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.	got7fsn_ti	collagen fibril organisation|fibrillar collagen organization													biological_process											owl:Class	
GO:0043448	biolink:NamedThing	alkane catabolic process	The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.	got7fsn_ti	alkane breakdown|alkane catabolism|alkane degradation													biological_process											owl:Class	
GO:0010274	biolink:NamedThing	hydrotropism	Growth or movement in a sessile organism toward or away from water, as of the roots of a plant.	got7fsn_ti												Wikipedia:Hydrotropism		biological_process											owl:Class	
GO:0051031	biolink:NamedThing	tRNA transport	The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0016720	biolink:NamedThing	delta12-fatty acid dehydrogenase activity	Catalysis of the reaction: AH(2) + linoleate + O(2) = A + crepenynate + 2 H(2)O.	got7fsn_ti	delta-12 fatty acid acetylenase activity|crepenynate synthase activity|linoleate delta-12-fatty acid acetylenase (desaturase) activity|linoleate delta12-fatty acid acetylenase (desaturase)|delta12 fatty acid acetylenase activity|D12-fatty acid dehydrogenase activity|linoleate, hydrogen-donor:oxygen oxidoreductase (Delta12-unsaturating)											RHEA:23456|KEGG_REACTION:R05740|EC:1.14.99.33|MetaCyc:1.14.99.33-RXN		molecular_function											owl:Class	
GO:0000286	biolink:NamedThing	alanine dehydrogenase activity	Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+).	got7fsn_ti	alanine oxidoreductase activity|L-alanine:NAD+ oxidoreductase (deaminating)|alpha-alanine dehydrogenase activity|NAD-linked alanine dehydrogenase activity|NADH-dependent alanine dehydrogenase activity|AlaDH|L-alanine dehydrogenase activity|NAD-dependent alanine dehydrogenase activity											RHEA:18405|MetaCyc:ALANINE-DEHYDROGENASE-RXN|EC:1.4.1.1		molecular_function											owl:Class	
GO:0102774	biolink:NamedThing	p-coumaroyltriacetic acid lactone synthase activity	Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide.	got7fsn_ti												MetaCyc:RXN-7822		molecular_function											owl:Class	
GO:0016269	biolink:NamedThing	O-glycan processing, core 3	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc.	got7fsn_ti														biological_process											owl:Class	
GO:0047818	biolink:NamedThing	D-fuconate dehydratase activity	Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H(2)O.	got7fsn_ti	D-fuconate hydro-lyase activity|D-fuconate hydro-lyase (2-dehydro-3-deoxy-D-fuconate-forming)|D-fuconate hydratase activity											MetaCyc:D-FUCONATE-HYDRATASE-RXN|RHEA:12949|EC:4.2.1.67|KEGG_REACTION:R03671		molecular_function											owl:Class	
GO:0099051	biolink:NamedThing	vesicle scission involved in endocytosis	The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0099050	biolink:NamedThing	vesicle scission	The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0036016	biolink:NamedThing	cellular response to interleukin-3	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.	got7fsn_ti	cellular response to IL-3						bf	2011-10-12T10:09:10Z						biological_process											owl:Class	
GO:0036015	biolink:NamedThing	response to interleukin-3	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.	got7fsn_ti	response to IL-3						bf	2011-10-12T10:08:26Z						biological_process											owl:Class	
GO:0051786	biolink:NamedThing	all-trans-retinol 13,14-reductase activity	Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction.	got7fsn_ti	RetSat activity|all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase activity|all-trans-retinol:all-trans-13,14-dihydroretinol saturase activity|(13,14)-all-trans-retinol saturase activity|retinol saturase activity											MetaCyc:1.3.99.23-RXN|KEGG_REACTION:R07163|RHEA:19193|EC:1.3.99.23|Reactome:R-HSA-8956427		molecular_function											owl:Class	
GO:0030277	biolink:NamedThing	maintenance of gastrointestinal epithelium	Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents.	got7fsn_ti														biological_process											owl:Class	
GO:0042409	biolink:NamedThing	caffeoyl-CoA O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.	got7fsn_ti	S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity|caffeoyl coenzyme A methyltransferase activity|caffeoyl-CoA 3-O-methyltransferase activity|trans-caffeoyl-CoA 3-O-methyltransferase activity											MetaCyc:CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN|RHEA:16925|EC:2.1.1.104		molecular_function											owl:Class	
GO:0032898	biolink:NamedThing	neurotrophin production	The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.	got7fsn_ti														biological_process											owl:Class	
GO:0010199	biolink:NamedThing	organ boundary specification between lateral organs and the meristem	The process in which boundaries between lateral organs and the meristem is established and maintained.	got7fsn_ti														biological_process											owl:Class	
GO:0036368	biolink:NamedThing	cone photoresponse recovery	The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers.	got7fsn_ti	cone phototransduction termination|cone response recovery						bf	2012-09-26T14:35:20Z						biological_process											owl:Class	
GO:0050372	biolink:NamedThing	ubiquitin-calmodulin ligase activity	Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin.	got7fsn_ti	uCaM-synthetase activity|ubiquityl-calmodulin synthase activity|ubiquitin-calmodulin synthetase activity|ubiquityl-calmodulin synthetase activity|calmodulin:ubiquitin ligase (AMP-forming)											MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN		molecular_function											owl:Class	
GO:0031025	biolink:NamedThing	equatorial microtubule organizing center disassembly	The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis.	got7fsn_ti	equatorial microtubule organising center disassembly													biological_process											owl:Class	
GO:0061592	biolink:NamedThing	phosphatidylserine exposure on osteoblast involved in bone mineralization	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization.	got7fsn_ti							dph	2014-02-05T15:27:39Z						biological_process											owl:Class	
GO:0002149	biolink:NamedThing	hypochlorous acid biosynthetic process	The chemical reactions and pathways resulting in the formation of hypochlorous acid.	got7fsn_ti	hypochlorite biosynthetic process|HClO biosynthetic process|hypochlorous acid biosynthesis|HOCl biosynthetic process				Note that this reaction is catalyzed by myeloperoxidase in neutrophils.		hjd	2009-10-13T10:32:35Z						biological_process											owl:Class	
GO:0103016	biolink:NamedThing	tRNA-specific 2-thiouridylase activity	Catalysis of the reaction: ATP + H+ + a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine = AMP + diphosphoric acid + a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine.	got7fsn_ti												MetaCyc:RXN0-2023		molecular_function											owl:Class	
GO:0052716	biolink:NamedThing	hydroquinone:oxygen oxidoreductase activity	Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O.	got7fsn_ti	p-diphenol:oxygen oxidoreductase activity|laccase reaction|benzenediol:oxygen oxidoreductase activity						ai	2011-08-11T03:18:19Z				EC:1.10.3.2|RHEA:11276|MetaCyc:LACCASE-RXN|KEGG_REACTION:R00083		molecular_function											owl:Class	
GO:0008825	biolink:NamedThing	cyclopropane-fatty-acyl-phospholipid synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.	got7fsn_ti	cyclopropane fatty acid synthase activity|cyclopropane fatty acid synthetase activity|cyclopropane synthase activity|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing)|cyclopropane synthetase activity|unsaturated-phospholipid methyltransferase activity|CFA synthase activity											EC:2.1.1.79|MetaCyc:2.1.1.79-RXN|RHEA:11988		molecular_function											owl:Class	
GO:0090274	biolink:NamedThing	positive regulation of somatostatin secretion	Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.	got7fsn_ti							tb	2010-02-05T02:54:14Z						biological_process											owl:Class	
GO:0021509	biolink:NamedThing	roof plate formation	The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.	got7fsn_ti														biological_process											owl:Class	
GO:0034735	biolink:NamedThing	transcription factor TFIIIC2 complex	A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter.	got7fsn_ti														cellular_component											owl:Class	
GO:0031101	biolink:NamedThing	fin regeneration	The regrowth of fin tissue following its loss or destruction.	got7fsn_ti														biological_process											owl:Class	
GO:0047683	biolink:NamedThing	aryl-aldehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP.	got7fsn_ti	aryl-aldehyde:NADP+ oxidoreductase (ATP-forming)|aromatic acid reductase activity											RHEA:19229|MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-NADP+-RXN|EC:1.2.1.30		molecular_function											owl:Class	
GO:0071092	biolink:NamedThing	alpha3-beta1 integrin-tissue transglutaminase complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.	got7fsn_ti	ITGA3-ITGB1-TGM2 complex						mah	2009-11-06T04:47:04Z						cellular_component											owl:Class	
GO:0052656	biolink:NamedThing	L-isoleucine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid.	got7fsn_ti	L-isoleucine aminotransferase activity											KEGG_REACTION:R02199|EC:2.6.1.42|RHEA:24801|MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN		molecular_function											owl:Class	
GO:0008214	biolink:NamedThing	protein dealkylation	The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.	got7fsn_ti	protein amino acid dealkylation													biological_process											owl:Class	
GO:0010508	biolink:NamedThing	positive regulation of autophagy	Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	got7fsn_ti														biological_process											owl:Class	
GO:0004145	biolink:NamedThing	diamine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.	got7fsn_ti	spermidine N(1)-acetyltransferase activity|acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase activity|acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase activity|spermine N-acetyltransferase|putrescine acetyltransferase activity|spermidine N1-acetyltransferase activity|putrescine acetylase activity|spermidine acetyltransferase activity|spermidine/spermine N1-acetyltransferase activity|spermine acetyltransferase|spermine N(1)-acetyltransferase|putrescine (diamine)-acetylating enzyme activity|diamine acetyltransferase activity|putrescine N-acetyltransferase activity											MetaCyc:DIAMACTRANS-RXN|EC:2.3.1.57|Reactome:R-HSA-351208|Reactome:R-HSA-351207|RHEA:25181		molecular_function											owl:Class	
GO:1900578	biolink:NamedThing	gerfelin biosynthetic process	The chemical reactions and pathways resulting in the formation of gerfelin.	got7fsn_ti	gerfelin biosynthesis|gerfelin anabolism|gerfelin formation|gerfelin synthesis						di	2012-05-15T06:42:47Z						biological_process											owl:Class	
GO:0050174	biolink:NamedThing	phenylalanine decarboxylase activity	Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2.	got7fsn_ti	L-phenylalanine carboxy-lyase (phenylethylamine-forming)|L-phenylalanine decarboxylase activity|aromatic L-amino acid decarboxylase activity|L-phenylalanine carboxy-lyase activity											MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN|RHEA:19717|EC:4.1.1.53		molecular_function											owl:Class	
GO:0006287	biolink:NamedThing	base-excision repair, gap-filling	Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template.	got7fsn_ti														biological_process											owl:Class	
GO:0047765	biolink:NamedThing	caldesmon-phosphatase activity	Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate.	got7fsn_ti	SMP-I|caldesmon-phosphate phosphohydrolase activity|smooth muscle caldesmon phosphatase activity											EC:3.1.3.55|MetaCyc:CALDESMON-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:1990211	biolink:NamedThing	positive regulation by symbiont of jasmonic acid levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-09T18:58:37Z						biological_process											owl:Class	
GO:0047199	biolink:NamedThing	phosphatidylcholine-dolichol O-acyltransferase activity	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol.	got7fsn_ti	3-sn-phosphatidylcholine:dolichol O-acyltransferase activity											MetaCyc:2.3.1.83-RXN|RHEA:19285|KEGG_REACTION:R04227|EC:2.3.1.83		molecular_function											owl:Class	
GO:0045900	biolink:NamedThing	negative regulation of translational elongation	Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.	got7fsn_ti	downregulation of translational elongation|down regulation of translational elongation|inhibition of translational elongation|down-regulation of translational elongation													biological_process											owl:Class	
GO:0097214	biolink:NamedThing	positive regulation of lysosomal membrane permeability	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.	got7fsn_ti	positive regulation of lysosome membrane permeability						pr	2012-01-12T10:22:17Z						biological_process											owl:Class	
GO:0009742	biolink:NamedThing	brassinosteroid mediated signaling pathway	A series of molecular signals mediated by the detection of brassinosteroid.	got7fsn_ti	brassinosteroid mediated signalling													biological_process											owl:Class	
GO:0080043	biolink:NamedThing	quercetin 3-O-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0047147	biolink:NamedThing	trimethylsulfonium-tetrahydrofolate N-methyltransferase activity	Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+).	got7fsn_ti	trimethylsulfonium-tetrahydrofolate methyltransferase activity|trimethylsulfonium:tetrahydrofolate N-methyltransferase activity|trimethylsulphonium-tetrahydrofolate N-methyltransferase activity											RHEA:13693|EC:2.1.1.19|MetaCyc:2.1.1.19-RXN|KEGG_REACTION:R02573		molecular_function											owl:Class	
GO:0051412	biolink:NamedThing	response to corticosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.	got7fsn_ti	response to corticosterone stimulus													biological_process											owl:Class	
GO:0051385	biolink:NamedThing	response to mineralocorticoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.	got7fsn_ti	response to mineralocorticoid stimulus													biological_process											owl:Class	
GO:0071948	biolink:NamedThing	activation-induced B cell apoptotic process	B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death.	got7fsn_ti	activation-induced cell death of B lymphocytes|antigen-driven apoptosis|activation-induced cell death of B-lymphocytes|activation-induced cell death of B-cells|AICD|activation-induced cell death of B cells|activation-induced B cell apoptosis|activated B cell apoptosis|activation-induced B-cell apoptosis						mah	2010-10-06T02:47:46Z						biological_process											owl:Class	
GO:0050479	biolink:NamedThing	glyceryl-ether monooxygenase activity	Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine).	got7fsn_ti	glyceryl-ether cleaving enzyme activity|alkylglycerol monooxygenase activity|glyceryl etherase activity|O-alkylglycerol monooxygenase activity|glyceryl ether oxygenase activity|1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase activity											EC:1.14.16.5|RHEA:36255|MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN|Reactome:R-HSA-5696119		molecular_function											owl:Class	
GO:0043664	biolink:NamedThing	host peribacteroid membrane	A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).	got7fsn_ti														cellular_component											owl:Class	
GO:0015919	biolink:NamedThing	peroxisomal membrane transport	The directed movement of substances to, from or across the peroxisomal membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0043574	biolink:NamedThing	peroxisomal transport	Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0004735	biolink:NamedThing	pyrroline-5-carboxylate reductase activity	Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.	got7fsn_ti	L-proline oxidase activity|NADPH-L-delta1-pyrroline carboxylic acid reductase activity|P5CR activity|L-proline:NAD(P)+ 5-oxidoreductase activity|L-proline-NAD(P)+ 5-oxidoreductase activity|1-pyrroline-5-carboxylate reductase activity											EC:1.5.1.2|Reactome:R-HSA-6783955|RHEA:14109|MetaCyc:PYRROLINECARBREDUCT-RXN|Reactome:R-HSA-70664|Reactome:R-HSA-6783939		molecular_function											owl:Class	
GO:0070181	biolink:NamedThing	small ribosomal subunit rRNA binding	Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.	got7fsn_ti	SSU rRNA binding|18S rRNA binding													molecular_function											owl:Class	
GO:0033832	biolink:NamedThing	alpha,alpha-trehalose phosphorylase (configuration-retaining) activity	Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.	got7fsn_ti	alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase activity|trehalose phosphorylase activity											MetaCyc:RXN-4441|RHEA:16257		molecular_function											owl:Class	
GO:0043805	biolink:NamedThing	indolepyruvate ferredoxin oxidoreductase activity	Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin.	got7fsn_ti	IOR|indolepyruvate oxidoreductase activity|3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating, CoA-indole-acetylating)|3-(indol-3-yl)pyruvate synthase (ferredoxin) activity											EC:1.2.7.8|MetaCyc:1.2.7.8-RXN|RHEA:12645		molecular_function											owl:Class	
GO:0102333	biolink:NamedThing	stearoyl-[acp] elongase/decarboxylase activity	Catalysis of the reaction: malonyl-CoA + 3 H+ + a stearoyl-[acp] = nonadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-13261		molecular_function											owl:Class	
GO:0046745	biolink:NamedThing	viral capsid secondary envelopment	The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope.	got7fsn_ti	Golgi membrane viral budding during viral capsid re-envelopment|virus budding from inner nuclear membrane by viral capsid re-envelopment|virus budding from Golgi membrane by viral capsid re-envelopment|virus budding from nuclear membrane during viral capsid re-envelopment|viral capsid re-envelopment|endoplasmic reticulum membrane viral budding during viral capsid re-envelopment|viral budding from nuclear membrane during viral capsid re-envelopment|viral budding from inner nuclear membrane by viral capsid re-envelopment|virus budding from ER membrane during viral capsid re-envelopment|viral budding from Golgi membrane by viral capsid re-envelopment|ER membrane viral budding during viral capsid re-envelopment|viral budding from Golgi membrane during viral capsid re-envelopment|nuclear membrane viral budding during viral capsid re-envelopment|virus budding from outer nuclear membrane during viral capsid re-envelopment|virus budding from nuclear membrane by viral capsid re-envelopment|viral budding from plasma membrane by viral capsid re-envelopment|virus budding from Golgi membrane during viral capsid re-envelopment|viral budding from nuclear membrane by viral capsid re-envelopment|virus budding from plasma membrane during viral capsid re-envelopment|virus budding from ER membrane by viral capsid re-envelopment|viral budding from inner nuclear membrane during viral capsid re-envelopment|virus budding from inner nuclear membrane during viral capsid re-envelopment|viral budding from plasma membrane during viral capsid re-envelopment|virus budding from outer nuclear membrane by viral capsid re-envelopment|viral budding from ER membrane by viral capsid re-envelopment|inner nuclear membrane viral budding during viral capsid re-envelopment|viral budding from outer nuclear membrane by viral capsid re-envelopment|viral budding from ER membrane during viral capsid re-envelopment|viral budding from outer nuclear membrane during viral capsid re-envelopment|plasma membrane viral budding during viral capsid re-envelopment|outer nuclear membrane viral budding during viral capsid re-envelopment										GO:0046770|GO:0046747|GO:0046769|GO:0046768|GO:0046746|GO:0046748			biological_process											owl:Class	
GO:0102183	biolink:NamedThing	avenastenone reductase activity	Catalysis of the reaction: avenastenone + NADPH + H+ <=> avenasterol + NADP.	got7fsn_ti												MetaCyc:RXN-11939		molecular_function											owl:Class	
GO:0042406	biolink:NamedThing	extrinsic component of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to ER membrane|extrinsic to endoplasmic reticulum membrane													cellular_component											owl:Class	
GO:0048485	biolink:NamedThing	sympathetic nervous system development	The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.	got7fsn_ti														biological_process											owl:Class	
GO:0033723	biolink:NamedThing	fluoroacetaldehyde dehydrogenase activity	Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.	got7fsn_ti	fluoroacetaldehyde:NAD+ oxidoreductase activity											EC:1.2.1.69|RHEA:16677		molecular_function											owl:Class	
GO:0102502	biolink:NamedThing	ADP-glucose-starch glucosyltransferase activity	Catalysis of the reaction: ADP alpha-D-glucoside + n a 1,4-alpha-D-glucan = ADP + n alpha-amylose.	got7fsn_ti												EC:2.4.1.242|MetaCyc:RXN-14378		molecular_function											owl:Class	
GO:0050674	biolink:NamedThing	urothelial cell proliferation	The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.	got7fsn_ti														biological_process											owl:Class	
GO:0031089	biolink:NamedThing	platelet dense granule lumen	The volume enclosed by the membrane of the platelet dense granule.	got7fsn_ti														cellular_component											owl:Class	
GO:0050121	biolink:NamedThing	N-acylglucosamine 2-epimerase activity	Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine.	got7fsn_ti	N-acyl-D-glucosamine 2-epimerase activity|GlcNAc 2-epimerase activity|acylglucosamine 2-epimerase activity|N-acetyl-D-glucosamine 2-epimerase activity|N-acetylglucosamine 2-epimerase activity											EC:5.1.3.8|Reactome:R-HSA-6803761|RHEA:19033|MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN		molecular_function											owl:Class	
GO:1900590	biolink:NamedThing	violaceol I biosynthetic process	The chemical reactions and pathways resulting in the formation of violaceol I.	got7fsn_ti	violaceol I formation|violaceol I synthesis|violaceol I biosynthesis|violaceol I anabolism						di	2012-05-15T06:51:16Z						biological_process											owl:Class	
GO:0050622	biolink:NamedThing	glycine dehydrogenase (cyanide-forming) activity	Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.	got7fsn_ti	glycine:acceptor oxidoreductase (hydrogen-cyanide-forming)|HCN synthase activity|hydrogen cyanide synthase activity											MetaCyc:1.4.99.5-RXN|RHEA:15821|EC:1.4.99.5		molecular_function											owl:Class	
GO:0043528	biolink:NamedThing	tRNA (m2G10) methyltransferase complex	A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p.	got7fsn_ti														cellular_component											owl:Class	
GO:0070876	biolink:NamedThing	SOSS complex	A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.	got7fsn_ti							mah	2009-08-20T03:30:48Z						cellular_component											owl:Class	
GO:0031755	biolink:NamedThing	Edg-2 lysophosphatidic acid receptor binding	Binding to an Edg-2 lysophosphatidic acid receptor.	got7fsn_ti	Edg-2 lysophosphatidic acid receptor ligand|LPA1 receptor binding													molecular_function											owl:Class	
GO:0033452	biolink:NamedThing	GUG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GUG codon.	got7fsn_ti	valine tRNA|GTG codon-amino acid adaptor activity				Note that in the standard genetic code, GTG codes for valine.									molecular_function											owl:Class	
GO:0047284	biolink:NamedThing	dolichyl-xylosyl-phosphate-protein xylosyltransferase activity	Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein.	got7fsn_ti	dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase activity											EC:2.4.2.33|MetaCyc:2.4.2.33-RXN|RHEA:18361		molecular_function											owl:Class	
GO:0042152	biolink:NamedThing	RNA-mediated DNA recombination	The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele.	got7fsn_ti														biological_process											owl:Class	
GO:0008996	biolink:NamedThing	ribonuclease G activity	Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.	got7fsn_ti														molecular_function											owl:Class	
GO:0047619	biolink:NamedThing	acylcarnitine hydrolase activity	Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine.	got7fsn_ti	carnitine ester hydrolase activity|palmitoyl carnitine hydrolase activity|O-acylcarnitine acylhydrolase activity|high activity acylcarnitine hydrolase activity|palmitoyl-L-carnitine hydrolase activity|long-chain acyl-L-carnitine hydrolase activity|palmitoylcarnitine hydrolase activity|HACH											RHEA:17101|MetaCyc:ACYLCARNITINE-HYDROLASE-RXN|EC:3.1.1.28		molecular_function											owl:Class	
GO:0097133	biolink:NamedThing	cyclin D3-CDK6 complex	A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:57:41Z						cellular_component											owl:Class	
GO:0035455	biolink:NamedThing	response to interferon-alpha	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.	got7fsn_ti	response to interferon alfa-n1|response to leukocyte interferon|response to lymphoblast interferon|response to interferon alfa-n3|response to lymphoblastoid interferon						bf	2010-04-16T10:57:16Z						biological_process											owl:Class	
GO:0000933	biolink:NamedThing	adventitious septum	A cell septum whose formation is independent of nuclear division.	got7fsn_ti														cellular_component											owl:Class	
GO:0047091	biolink:NamedThing	L-lysine 6-monooxygenase (NADPH) activity	Catalysis of the reaction: L-lysine + NADPH + O(2) = N(6)-hydroxy-L-lysine + H(2)O + NADP(+).	got7fsn_ti	L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)|L-lysine 6-monooxygenase activity|lysine N(6)-hydroxylase activity|lysine N6-hydroxylase activity				Note that EC:1.13.12.10 was merged into this term.						GO:0008739	KEGG_REACTION:R00448|RHEA:23228|EC:1.14.13.59|MetaCyc:1.14.13.59-RXN		molecular_function											owl:Class	
GO:0018134	biolink:NamedThing	peptide cross-linking via glycine oxazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	got7fsn_ti												RESID:AA0240		biological_process											owl:Class	
GO:0018713	biolink:NamedThing	3-ketopimelyl-CoA thiolase activity	Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0197|MetaCyc:RXN-8032		molecular_function											owl:Class	
GO:1904949	biolink:NamedThing	ATPase complex	A protein complex which is capable of ATPase activity.	got7fsn_ti	VPS4 complex				An example of this is VPS4 in Saccharomyces cerevisiae (UniProt ID P52917) in PMID:9606181 (inferred from direct assay).		bhm	2016-02-04T22:13:32Z						cellular_component											owl:Class	
GO:0102562	biolink:NamedThing	hydroxyproline O-arbinofuranose transferase activity	Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline = UDP + H+ + a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline.	got7fsn_ti												MetaCyc:RXN-15011|RHEA:49472		molecular_function											owl:Class	
GO:0030290	biolink:NamedThing	sphingolipid activator protein activity	Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase.	got7fsn_ti	saposin											Reactome:R-HSA-1605717		molecular_function											owl:Class	
GO:0003130	biolink:NamedThing	BMP signaling pathway involved in heart induction	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to heart induction.	got7fsn_ti	BMP signalling pathway involved in heart induction						tb	2009-09-22T03:02:00Z						biological_process											owl:Class	
GO:0033977	biolink:NamedThing	2-haloacid dehalogenase (configuration-retaining) activity	Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.	got7fsn_ti	DL-DEXr|2-haloalkanoid acid halidohydrolase activity|2-haloalkanoic acid dehalogenase activity|DL-2-haloacid dehalogenase activity											EC:3.8.1.11|MetaCyc:3.8.1.11-RXN|RHEA:12072		molecular_function											owl:Class	
GO:0045920	biolink:NamedThing	negative regulation of exocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.	got7fsn_ti	down-regulation of exocytosis|inhibition of exocytosis|down regulation of exocytosis|downregulation of exocytosis													biological_process											owl:Class	
GO:0070524	biolink:NamedThing	11-beta-hydroxysteroid dehydrogenase (NADP+) activity	Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.	got7fsn_ti	beta-hydroxysteroid dehydrogenase|corticosteroid 11-beta-dehydrogenase activity											EC:1.1.1.146|Wikipedia:11beta-hydroxysteroid_dehydrogenase|RHEA:11388|MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0033015	biolink:NamedThing	tetrapyrrole catabolic process	The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.	got7fsn_ti	tetrapyrrole breakdown|tetrapyrrole catabolism|tetrapyrrole degradation													biological_process											owl:Class	
GO:0098886	biolink:NamedThing	modification of dendritic spine	Any process that modifies the structure of a dendritic spine.	got7fsn_ti					This class does not cover assembly or disassembly of dendritic spines, only the modification/remodelling of existing ones.									biological_process											owl:Class	
GO:0071954	biolink:NamedThing	chemokine (C-C motif) ligand 11 production	The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	CCL11 production|eotaxin-1 production|eotaxin production|C-C motif chemokine 11 production|CCL-11 production						mah	2010-10-08T12:10:34Z						biological_process											owl:Class	
GO:1990465	biolink:NamedThing	aldehyde oxygenase (deformylating) activity	Catalysis of the reaction a long-chain aldehyde + O(2) + 2 NADPH = an alkane + formate + H(2)O + 2 NADP(+).	got7fsn_ti							tt	2014-08-25T15:16:43Z				RHEA:21440|EC:4.1.99.5		molecular_function											owl:Class	
GO:0102963	biolink:NamedThing	(S)-corytuberine synthase activity	Catalysis of the reaction: H+ + (S)-reticulinium(1+) + NADPH + O2 <=> (S)-corytuberine + NADP + 2 H2O.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21133										RHEA:51540|MetaCyc:RXN-9314|EC:1.14.19.51		molecular_function											owl:Class	
GO:1901097	biolink:NamedThing	negative regulation of autophagosome maturation	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation.	got7fsn_ti	negative regulation of amphisome-lysosome fusion|down-regulation of autophagic vacuole maturation|negative regulation of autophagic vacuole fusion|down-regulation of autophagic vacuole fusion|inhibition of fusion of autophagosome with lysosome|inhibition of amphisome-lysosome fusion|inhibition of autophagic vacuole fusion|downregulation of autophagic vacuole fusion|negative regulation of autophagosome maturation|downregulation of autolysosome formation|downregulation of autophagic vacuole maturation|negative regulation of autolysosome formation|down-regulation of autophagosome maturation|downregulation of amphisome-lysosome fusion|inhibition of autolysosome formation|down-regulation of fusion of autophagosome with lysosome|negative regulation of autophagosome fusion|down regulation of amphisome-lysosome fusion|down regulation of autophagic vacuole fusion|negative regulation of fusion of autophagosome with lysosome|inhibition of autophagic vacuole maturation|inhibition of autophagosome maturation|down regulation of autophagic vacuole maturation|down regulation of fusion of autophagosome with lysosome|down-regulation of autolysosome formation|downregulation of autophagosome maturation|downregulation of fusion of autophagosome with lysosome|down regulation of autophagosome maturation|down-regulation of amphisome-lysosome fusion|down regulation of autolysosome formation						lb	2012-07-10T07:22:26Z			GO:1902453			biological_process											owl:Class	
GO:0016242	biolink:NamedThing	negative regulation of macroautophagy	Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.	got7fsn_ti	inhibition of macroautophagy|negative regulation of starvation-induced autophagy|downregulation of macroautophagy|down regulation of macroautophagy|down-regulation of macroautophagy													biological_process											owl:Class	
GO:0010290	biolink:NamedThing	chlorophyll catabolite transmembrane transporter activity	Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0014706	biolink:NamedThing	striated muscle tissue development	The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.	got7fsn_ti														biological_process											owl:Class	
GO:0018112	biolink:NamedThing	proline racemase activity	Catalysis of the reaction: L-proline = D-proline.	got7fsn_ti												KEGG_REACTION:R01255|RHEA:10680|EC:5.1.1.4|MetaCyc:PROLINE-RACEMASE-RXN		molecular_function											owl:Class	
GO:0008532	biolink:NamedThing	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.	got7fsn_ti	uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase|uridine diphosphoacetylglucosamine-acetyllactosaminide beta-1,3-acetylglucosaminyltransferase|UDP-GlcNAc:Galbeta-(1,4)-GlcNAcbeta-r-beta-(1,3)-N-acetylglucosaminyltransferase activity|galbeta1->4GlcNAc-R beta1->3 N-acetylglucosaminyltransferase activity|UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosamine beta-1,3-acetyl-D-glucosaminyltransferase activity|GnTE activity|UDP-GlcNAc:Galbeta-1,4-GlcNAcbeta-beta-1,3-N-acetylglucosaminyltransferase activity|N-acetyllactosamine beta(1,3)N-acetylglucosaminyltransferase activity|poly-N-acetyllactosamine extension enzyme activity											RHEA:14389|MetaCyc:2.4.1.149-RXN|EC:2.4.1.149|Reactome:R-HSA-2025724		molecular_function											owl:Class	
GO:0050053	biolink:NamedThing	levansucrase activity	Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1).	got7fsn_ti	sucrose 6-fructosyl transferase activity|beta-2,6-fructan:D-glucose 1-fructosyltransferase activity|sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase activity|sucrose 6-fructosyltransferase activity|beta-2,6-fructosyltransferase activity											EC:2.4.1.10|MetaCyc:LEVANSUCRASE-RXN|RHEA:13653		molecular_function											owl:Class	
GO:0018601	biolink:NamedThing	4-nitrophenol 2-monooxygenase activity	Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+).	got7fsn_ti	4-nitrophenol hydroxylase activity|4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)|4-nitrophenol-2-hydroxylase activity											RHEA:12568|EC:1.14.13.29|KEGG_REACTION:R03023|UM-BBD_reactionID:r0230|MetaCyc:4-NITROPHENOL-2-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0018651	biolink:NamedThing	toluene-4-sulfonate monooxygenase activity	Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene.	got7fsn_ti	toluene-4-sulphonate monooxygenase activity											UM-BBD_reactionID:r0296|EC:1.14.13.-		molecular_function											owl:Class	
GO:0043328	biolink:NamedThing	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.	got7fsn_ti	protein-vacuolar targeting during ubiquitin-dependent protein degradation via the MVB pathway|protein-vacuolar targeting during ubiquitin-dependent protein breakdown via the MVB pathway|protein vacuolar targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein-vacuole targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein breakdown via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein degradation via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway|protein-vacuole targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein vacuolar targeting during ubiquitin-dependent protein catabolism via the MVB pathway													biological_process											owl:Class	
GO:0003854	biolink:NamedThing	3-beta-hydroxy-delta5-steroid dehydrogenase activity	Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+).	got7fsn_ti	3beta-hydroxy steroid dehydrogenase/isomerase activity|3-beta-hydroxy-D5-steroid dehydrogenase activity|3beta-hydroxy-delta5-C27-steroid oxidoreductase|delta5-3beta-hydroxysteroid dehydrogenase activity|3beta-hydroxy-5-ene-steroid dehydrogenase activity|progesterone reductase activity|3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity|3beta-HSDH|steroid-delta5-3beta-ol dehydrogenase activity|3beta-hydroxy-delta5-steroid dehydrogenase activity|3beta-hydroxy-5-ene steroid dehydrogenase activity|3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity|3beta-hydroxy-5-ene-steroid oxidoreductase activity|3-beta-hydroxy-5-ene steroid dehydrogenase activity|5-ene-3-beta-hydroxysteroid dehydrogenase activity											MetaCyc:1.1.1.145-RXN|Reactome:R-HSA-192097|Reactome:R-HSA-196372|Reactome:R-HSA-193789|Reactome:R-HSA-196350|RHEA:24076|EC:1.1.1.145|Reactome:R-HSA-193816		molecular_function											owl:Class	
GO:0071532	biolink:NamedThing	ankyrin repeat binding	Binding to an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure.	got7fsn_ti	ANK repeat binding						mah	2010-01-08T02:21:02Z						molecular_function											owl:Class	
GO:0008447	biolink:NamedThing	L-ascorbate oxidase activity	Catalysis of the reaction: 4 L-ascorbate + O(2) <=> 4 monodehydroascorbate + 2 H(2)O.	got7fsn_ti	ascorbase activity|ascorbate oxidase activity|AAO|ascorbate dehydrogenase activity|L-ascorbate:O2 oxidoreductase activity|ascorbic oxidase activity|L-ascorbic acid oxidase activity|AA oxidase activity|ascorbic acid oxidase activity|L-ascorbate:oxygen oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/21022										EC:1.10.3.3|RHEA:30243|MetaCyc:L-ASCORBATE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0035357	biolink:NamedThing	peroxisome proliferator activated receptor signaling pathway	The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes.	got7fsn_ti	peroxisome proliferator activated receptor signalling pathway|PPAR signaling pathway|peroxisome proliferator-activated receptor signaling pathway						bf	2010-03-05T10:30:10Z						biological_process											owl:Class	
GO:0035614	biolink:NamedThing	snRNA stem-loop binding	Binding to a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.	got7fsn_ti	snRNA hairpin loop binding|small nuclear RNA stem-loop binding|snRNA hairpin binding						bf	2010-11-26T10:43:17Z						molecular_function											owl:Class	
GO:0042725	biolink:NamedThing	thiamine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.	got7fsn_ti	thiamine-containing compound degradation|vitamin B1 and derivative catabolic process|thiamin-containing compound catabolic process|thiamin and derivative catabolic process|thiamine-containing compound breakdown|thiamine and derivative catabolic process|thiamine and derivative catabolism|thiamine-containing compound catabolism|vitamin B1 and derivative catabolism|thiamin and derivative catabolism													biological_process											owl:Class	
GO:0097710	biolink:NamedThing	viral terminase, small subunit	The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit.	got7fsn_ti	virus terminase, small subunit				This term should only be used when the small subunit consists of more than one polypeptide.		pr	2016-06-07T12:45:00Z						cellular_component											owl:Class	
GO:0070196	biolink:NamedThing	eukaryotic translation initiation factor 3 complex assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex.	got7fsn_ti	eIF-3 assembly|eIF3 assembly													biological_process											owl:Class	
GO:0045818	biolink:NamedThing	negative regulation of glycogen catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.	got7fsn_ti	downregulation of glycogen catabolic process|negative regulation of glycogen catabolism|negative regulation of glycogenolysis|negative regulation of glycogen degradation|inhibition of glycogen catabolic process|down-regulation of glycogen catabolic process|down regulation of glycogen catabolic process|negative regulation of glycogen breakdown													biological_process											owl:Class	
GO:0016985	biolink:NamedThing	mannan endo-1,4-beta-mannosidase activity	Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.	got7fsn_ti	endo-beta-mannanase activity|endo-1,4-mannanase activity|beta-mannanase activity|endo-beta-1,4-mannase activity|1,4-beta-D-mannan mannanohydrolase activity|beta-D-mannanase activity|beta-mannanase B|beta-1,4-mannan 4-mannanohydrolase activity|endo-1,4-beta-mannanase activity											MetaCyc:3.2.1.78-RXN|EC:3.2.1.78		molecular_function											owl:Class	
GO:0003270	biolink:NamedThing	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	Notch signaling pathway involved in regulation of second heart field cardioblast proliferation|Notch signalling pathway involved in regulation of secondary heart field cardioblast proliferation						dph	2009-10-15T02:47:00Z						biological_process											owl:Class	
GO:0061314	biolink:NamedThing	Notch signaling involved in heart development	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.	got7fsn_ti	Notch signalling involved in heart development						dph	2010-09-24T08:25:22Z						biological_process											owl:Class	
GO:0010611	biolink:NamedThing	regulation of cardiac muscle hypertrophy	Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0061153	biolink:NamedThing	trachea gland development	The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.	got7fsn_ti							dph	2010-06-07T10:10:51Z						biological_process											owl:Class	
GO:0103118	biolink:NamedThing	UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity	Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + an (3R)-3-hydroxymyristoyl-[acp] <=> UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H+ + a holo-[acyl-carrier protein].	got7fsn_ti	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity										GO:0043764	RHEA:17817|MetaCyc:UDPHYDROXYMYRGLUCOSAMNACETYLTRANS-RXN|EC:2.3.1.191		molecular_function											owl:Class	
GO:0016117	biolink:NamedThing	carotenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.	got7fsn_ti	carotenoid formation|carotenoid biosynthesis|carotenoid anabolism|carotenoid synthesis											MetaCyc:CAROTENOID-PWY		biological_process											owl:Class	
GO:0017061	biolink:NamedThing	S-methyl-5-thioadenosine phosphorylase activity	Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.	got7fsn_ti	MeSAdo/Ado phosphorylase activity|MeSAdo phosphorylase activity|5'-methylthioadenosine phosphorylase activity|5'-deoxy-5'-methylthioadenosine phosphorylase activity|methylthioadenosine phosphorylase activity|MTAPase activity|MTA phosphorylase activity|methylthioadenosine nucleoside phosphorylase activity|5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase activity|S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity											Reactome:R-HSA-1237160|EC:2.4.2.28|MetaCyc:5-METHYLTHIOADENOSINE-PHOSPHORYLASE-RXN|RHEA:11852		molecular_function											owl:Class	
GO:0006423	biolink:NamedThing	cysteinyl-tRNA aminoacylation	The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0047334	biolink:NamedThing	diphosphate-fructose-6-phosphate 1-phosphotransferase activity	Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate.	got7fsn_ti	pyrophosphate-dependent 6-phosphofructose-1-kinase activity|diphosphate:D-fructose-6-phosphate 1-phosphotransferase activity|6-phosphofructokinase (diphosphate) activity|diphosphate-dependent 6-phosphofructose-1-kinase activity|pyrophosphate-fructose 6-phosphate phosphotransferase activity|pyrophosphate-dependent phosphofructo-1-kinase activity|inorganic pyrophosphate-dependent phosphofructokinase activity|6-phosphofructokinase (pyrophosphate) activity|pyrophosphate--fructose 6-phosphate 1-phosphotransferase activity|inorganic pyrophosphate-phosphofructokinase activity											MetaCyc:2.7.1.90-RXN|RHEA:13613|EC:2.7.1.90		molecular_function											owl:Class	
GO:0102049	biolink:NamedThing	indole-3-acetyl-methionine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) <=> H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10431		molecular_function											owl:Class	
GO:0102454	biolink:NamedThing	cyanidin 3-O-galactosyltransferase activity	Catalysis of the reaction: cyanidin + UDP-D-galactose = cyanidin 3-O-beta-D-galactoside betaine + UDP.	got7fsn_ti												EC:2.4.1.294|RHEA:35631|MetaCyc:RXN-13960		molecular_function											owl:Class	
GO:0034283	biolink:NamedThing	syn-stemod-13(17)-ene synthase activity	Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate.	got7fsn_ti	exo-stemodene synthase activity|syn-stemodene synthase activity|stemod-13(17)-ene synthase activity|stemodene synthase activity|9alpha-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming] activity											RHEA:25556|KEGG_REACTION:R09116|MetaCyc:RXN-9291|EC:4.2.3.34		molecular_function											owl:Class	
GO:2000140	biolink:NamedThing	negative regulation of octopamine signaling pathway involved in response to food	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food.	got7fsn_ti	negative regulation of octopamine signalling pathway involved in response to food						mah	2010-09-30T02:48:10Z						biological_process											owl:Class	
GO:0032096	biolink:NamedThing	negative regulation of response to food	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.	got7fsn_ti	inhibition of response to food|down regulation of response to food|down-regulation of response to food|downregulation of response to food													biological_process											owl:Class	
GO:0015576	biolink:NamedThing	sorbitol transmembrane transporter activity	Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.	got7fsn_ti	glucitol permease activity|glucitol transporter activity|sorbitol permease activity										GO:0015587			molecular_function											owl:Class	
GO:0016629	biolink:NamedThing	12-oxophytodienoate reductase activity	Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + H(+) + NADPH.	got7fsn_ti	12-oxo-phytodienoic acid reductase activity|8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate:NADP+ 4-oxidoreductase activity|12-oxo-phytodienoate reductase activity											EC:1.3.1.42|RHEA:21888|MetaCyc:12-OXOPHYTODIENOATE-REDUCTASE-RXN|KEGG_REACTION:R03401		molecular_function											owl:Class	
GO:0050518	biolink:NamedThing	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate.	got7fsn_ti	MCT activity|4-diphosphocytidyl-2C-methyl-D-erythritol synthase activity|CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity|4-diphosphocytidyl-2-C-methyl-D-erythritol synthase activity|MEP cytidylyltransferase activity										GO:0008699	EC:2.7.7.60|KEGG_REACTION:R05633|RHEA:13429|MetaCyc:2.7.7.60-RXN		molecular_function											owl:Class	
GO:0034006	biolink:NamedThing	amorpha-4,11-diene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate.	got7fsn_ti	amorphadiene synthase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming) activity											MetaCyc:4.2.3.24-RXN|EC:4.2.3.24|RHEA:18325|KEGG_REACTION:R07630|MetaCyc:RXN-8046		molecular_function											owl:Class	
GO:0004654	biolink:NamedThing	polyribonucleotide nucleotidyltransferase activity	Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.	got7fsn_ti	polyribonucleotide:phosphate nucleotidyltransferase activity|polyribonucleotide phosphorylase activity|polynucleotide phosphorylase activity|nucleoside diphosphate:polynucleotidyl transferase activity											RHEA:22096|MetaCyc:2.7.7.8-RXN|EC:2.7.7.8		molecular_function											owl:Class	
GO:0017064	biolink:NamedThing	fatty acid amide hydrolase activity	Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.	got7fsn_ti											GO:0017073	Reactome:R-HSA-5693742|Reactome:R-HSA-5693751		molecular_function											owl:Class	
GO:0042299	biolink:NamedThing	lupeol synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.	got7fsn_ti	oxidosqualene:lupeol cyclase activity											EC:5.4.99.41|MetaCyc:RXN-111|RHEA:31383		molecular_function											owl:Class	
GO:0090036	biolink:NamedThing	regulation of protein kinase C signaling	Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	regulation of protein kinase C signalling cascade|regulation of protein kinase C signaling cascade						tb	2009-08-03T11:27:26Z						biological_process											owl:Class	
GO:0003359	biolink:NamedThing	noradrenergic neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron.	got7fsn_ti	norepinephrine secreting neuron fate commitment						dph	2009-12-03T10:41:08Z						biological_process											owl:Class	
GO:0060269	biolink:NamedThing	centripetally migrating follicle cell migration	The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.	got7fsn_ti														biological_process											owl:Class	
GO:0097259	biolink:NamedThing	20-aldehyde-leukotriene B4 20-monooxygenase activity	Catalysis of the reaction: 20-oxo-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H+ + H2O + oxidized [NADPH-hemoprotein reductase].	got7fsn_ti							pr	2012-03-07T03:40:05Z				Reactome:R-HSA-2161979|RHEA:48672|Reactome:R-HSA-2161792		molecular_function											owl:Class	
GO:0047629	biolink:NamedThing	ADP deaminase activity	Catalysis of the reaction: ADP + H2O = IDP + NH3.	got7fsn_ti	adenosine diphosphate deaminase activity|adenosinepyrophosphate deaminase activity|ADP aminohydrolase activity											MetaCyc:ADP-DEAMINASE-RXN|EC:3.5.4.7|RHEA:12741		molecular_function											owl:Class	
GO:0061455	biolink:NamedThing	integral component of muscle cell projection membrane	The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to muscle cell projection membrane						dph	2012-07-27T02:38:01Z						cellular_component											owl:Class	
GO:0071545	biolink:NamedThing	inositol phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	got7fsn_ti	inositol phosphate breakdown|inositol phosphate catabolism|inositol phosphate degradation|myo-inositol phosphate catabolic process				See also the biological process term 'inositol phosphate dephosphorylation ; GO:0046855'.		mah	2010-01-12T05:07:45Z						biological_process											owl:Class	
GO:0015451	biolink:NamedThing	decarboxylation-driven active transmembrane transporter activity	Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.	got7fsn_ti	decarboxylation-driven transporter											EC:7.2.4.1|TC:3.B|EC:7.2.4.2|EC:7.2.4.3|EC:7.2.4.5|EC:7.2.4.4		molecular_function											owl:Class	
GO:0021581	biolink:NamedThing	medulla oblongata structural organization	The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	got7fsn_ti	medulla structural maturation|medulla oblongata structural organisation|myelencephalon structural maturation													biological_process											owl:Class	
GO:0085015	biolink:NamedThing	dormancy maintenance of symbiont in host	Any process in which a dormant state is maintained by the symbiont within the host organism.	got7fsn_ti	non-replicating persistence|NRP						jl	2010-05-19T03:17:32Z						biological_process											owl:Class	
GO:0008672	biolink:NamedThing	2-dehydro-3-deoxyglucarate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde.	got7fsn_ti	2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming)|2-keto-3-deoxyglucarate aldolase activity|alpha-keto-beta-deoxy-D-glucarate aldolase activity|2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase activity											EC:4.1.2.20|RHEA:10268|MetaCyc:KDGALDOL-RXN		molecular_function											owl:Class	
GO:0102623	biolink:NamedThing	scutellarein 7-methyl ether 6-O-methyltransferase activity	Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine  <=> cirsimaritin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-15528		molecular_function											owl:Class	
GO:0039624	biolink:NamedThing	viral outer capsid	The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions.	got7fsn_ti	outer capsid						bf	2012-07-18T04:03:16Z						cellular_component											owl:Class	
GO:0045957	biolink:NamedThing	negative regulation of complement activation, alternative pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.	got7fsn_ti	down-regulation of complement activation, alternative pathway|downregulation of complement activation, alternative pathway|inhibition of complement activation, alternative pathway|negative regulation of complement cascade, alternative pathway|down regulation of complement activation, alternative pathway													biological_process											owl:Class	
GO:0140625	biolink:NamedThing	opioid growth factor receptor activity	Combining with the opioid growth factor (OGF, met-enkephalin) and transmitting the signal across the nuclear membrane. Met-enkephalin is an endogenous opioid peptide that binds to opioid and opioid growth factor receptors, regulating tissue growth in a variety of cellular processes.	got7fsn_ti	methionine enkephalin receptor activity|met-enkephalin receptor activity|metenkefalin receptor activity	https://github.com/geneontology/go-ontology/issues/21110					pg	2021-03-17T13:15:33Z						molecular_function											owl:Class	
GO:0140240	biolink:NamedThing	perforant pathway to dendrate granule cell synapse	A neuron to neuron synapse of a pyramidal neuron in the entorhinal cortex onto a granule cell in the dentate gyrus of the hippocampus.	got7fsn_ti	perforant pathway to DG granule cell synapse	https://github.com/geneontology/synapse/issues/234					pg	2018-07-15T08:21:43Z						cellular_component											owl:Class	
GO:0090640	biolink:NamedThing	phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine	The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine.	got7fsn_ti							tb	2015-04-23T15:56:12Z						biological_process											owl:Class	
GO:0000825	biolink:NamedThing	inositol tetrakisphosphate 6-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.	got7fsn_ti	inositol 1,3,4,5-tetrakisphosphate 6-kinase activity|1D-myo-inositol-tetrakisphosphate 6-kinase activity											MetaCyc:RXN-7184|Reactome:R-HSA-1855206		molecular_function											owl:Class	
GO:0050112	biolink:NamedThing	inositol 2-dehydrogenase activity	Catalysis of the reaction: myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + H(+) + NADH.	got7fsn_ti	inositol:NAD 2-dehydrogenase activity|myo-inositol 2-dehydrogenase activity											EC:1.1.1.18|MetaCyc:MYO-INOSITOL-2-DEHYDROGENASE-RXN|KEGG_REACTION:R01183|RHEA:16949		molecular_function											owl:Class	
GO:0075267	biolink:NamedThing	aecium development	The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium.	got7fsn_ti														biological_process											owl:Class	
GO:0034023	biolink:NamedThing	5-(carboxyamino)imidazole ribonucleotide mutase activity	Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.	got7fsn_ti	PurE|N5-CAIR mutase activity|class I PurE|5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase activity|N5-carboxyaminoimidazole ribonucleotide mutase activity											EC:5.4.99.18|RHEA:13193|MetaCyc:5.4.99.18-RXN		molecular_function											owl:Class	
GO:0046891	biolink:NamedThing	peptidyl-cysteine S-carbamoylation	The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine.	got7fsn_ti												RESID:AA0332		biological_process											owl:Class	
GO:0080069	biolink:NamedThing	7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate.	got7fsn_ti							dhl	2009-04-13T04:07:32Z				MetaCyc:RXNQT-4332		molecular_function											owl:Class	
GO:0018761	biolink:NamedThing	bromoxynil nitrilase activity	Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil.	got7fsn_ti	3,5-dibromo-4-hydroxybenzonitrile aminohydrolase activity|bromoxynil-specific nitrilase activity											MetaCyc:3.5.5.6-RXN|UM-BBD_enzymeID:e0357|EC:3.5.5.6|KEGG_REACTION:R04349|RHEA:22100		molecular_function											owl:Class	
GO:0046970	biolink:NamedThing	NAD-dependent histone deacetylase activity (H4-K16 specific)	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0110010	biolink:NamedThing	basolateral protein secretion	The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base.	got7fsn_ti							kmv							biological_process											owl:Class	
GO:0008843	biolink:NamedThing	endochitinase activity	Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0004568	biolink:NamedThing	chitinase activity	Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.	got7fsn_ti	beta-1,4-poly-N-acetyl glucosamidinase activity|poly-beta-glucosaminidase activity|poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity|1,4-beta-poly-N-acetylglucosaminidase activity|chitodextrinase activity											MetaCyc:3.2.1.14-RXN|Reactome:R-HSA-6786421|EC:3.2.1.14		molecular_function											owl:Class	
GO:0102631	biolink:NamedThing	caffeoylglucose 3-O-methyltransferase activity	Catalysis of the reaction: 1-O-caffeoyl-beta-D-glucose + S-adenosyl-L-methionine  <=> 1-O-feruloyl-beta-D-glucose + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-15537		molecular_function											owl:Class	
GO:0031594	biolink:NamedThing	neuromuscular junction	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.	got7fsn_ti	NMJ|motor endplate				In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are  cholinergic and excitatory.  Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.							Wikipedia:Neuromuscular_junction|NIF_Subcellular:sao1124888485		cellular_component											owl:Class	
GO:0071132	biolink:NamedThing	alphaX-beta2 integrin-ICAM-4 complex	A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4.	got7fsn_ti	ITGAX-ITGB2-ICAM4 complex						mah	2009-11-13T02:28:30Z						cellular_component											owl:Class	
GO:0001531	biolink:NamedThing	interleukin-21 receptor binding	Binding to an interleukin-21 receptor.	got7fsn_ti	IL-21|interleukin-21 receptor ligand													molecular_function											owl:Class	
GO:0035145	biolink:NamedThing	exon-exon junction complex	A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.	got7fsn_ti	EJC|exon junction complex													cellular_component											owl:Class	
GO:0017187	biolink:NamedThing	peptidyl-glutamic acid carboxylation	The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase.	got7fsn_ti					See also the molecular function term 'gamma-glutamyl carboxylase activity ; GO:0008488'.							RESID:AA0032		biological_process											owl:Class	
GO:0140291	biolink:NamedThing	peptidyl-glutamate ADP-deribosylation	The removal of ADP-ribose from ADP-ribosylglutamate.	got7fsn_ti							pg	2018-11-22T14:34:24Z						biological_process											owl:Class	
GO:0032623	biolink:NamedThing	interleukin-2 production	The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-2 secretion|interleukin-2 biosynthetic process|IL-2 production										GO:0070970|GO:0042094			biological_process											owl:Class	
GO:0098025	biolink:NamedThing	virus tail, baseplate	Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached.	got7fsn_ti	tail tip|tail structure|bacteriophage baseplate				Tail fibers are often attached to the baseplate of Caudovirales (tailed bacteriophages with dsDNA genomes). Sometimes referred to as the tail tip or tip structure in Siphoviridae.		bm	2012-07-19T14:16:51Z						cellular_component											owl:Class	
GO:0004996	biolink:NamedThing	thyroid-stimulating hormone receptor activity	Combining with thyroid-stimulating hormone to initiate a change in cell activity.	got7fsn_ti	TSH receptor activity|thyroid stimulating hormone receptor activity|thyrotropin receptor											Wikipedia:Thyrotropin_receptor		molecular_function											owl:Class	
GO:0003274	biolink:NamedThing	endocardial cushion fusion	The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping.	got7fsn_ti							dph	2009-10-20T09:26:32Z						biological_process											owl:Class	
GO:0031750	biolink:NamedThing	D3 dopamine receptor binding	Binding to a D3 dopamine receptor.	got7fsn_ti	D3 dopamine receptor ligand													molecular_function											owl:Class	
GO:0060408	biolink:NamedThing	regulation of acetylcholine metabolic process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0102138	biolink:NamedThing	7-oxatyphasterol synthase activity	Catalysis of the reaction: H+ + typhasterol + NADPH + O2 <=> 7-oxatyphasterol + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-11538		molecular_function											owl:Class	
OBO:CARO_0000000	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140133	biolink:NamedThing	suppression by symbiont of host cytokine production	Any process in which a symbiont stops, prevents, or reduces the rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	suppression by symbiont of host cytokine secretion|negative regulation by symbiont of host cytokine production	https://github.com/geneontology/go-ontology/issues/14553					pg	2017-11-14T07:07:04Z						biological_process											owl:Class	
GO:0033898	biolink:NamedThing	Bacillus subtilis ribonuclease activity	Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides.	got7fsn_ti	proteus mirabilis RNase activity|ribonucleate nucleotido-2'-transferase (cyclizing) activity											EC:4.6.1.22|MetaCyc:3.1.27.2-RXN		molecular_function											owl:Class	
GO:0071550	biolink:NamedThing	death-inducing signaling complex assembly	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway.	got7fsn_ti	DISC formation|death-inducing signalling complex assembly|death-inducing signaling complex formation|death domain-mediated complex assembly|DD-mediated complex assembly|DISC assembly|death domain-mediated complex assembly involved in extrinsic apoptotic pathway						mah	2010-01-13T02:48:38Z						biological_process											owl:Class	
GO:1990899	biolink:NamedThing	meiotic DNA double-strand break resectioning	The process following clipping in double-strand break processing of SPO11 induced breaks, where long-tract single-stranded 3'-end DNA is generated from naked (SPO11 has been removed) 5' ends.	got7fsn_ti							al	2015-11-10T17:23:07Z						biological_process											owl:Class	
GO:1900813	biolink:NamedThing	monodictyphenone metabolic process	The chemical reactions and pathways involving monodictyphenone.	got7fsn_ti	monodictyphenone metabolism						di	2012-06-04T10:11:03Z						biological_process											owl:Class	
GO:0097116	biolink:NamedThing	gephyrin clustering involved in postsynaptic density assembly	The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.	got7fsn_ti	Geph clustering						pr	2011-07-31T05:42:29Z						biological_process											owl:Class	
GO:0035418	biolink:NamedThing	protein localization to synapse	Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.	got7fsn_ti	protein localisation to synapse						bf	2010-03-29T10:58:53Z						biological_process											owl:Class	
GO:0044381	biolink:NamedThing	glucose import in response to insulin stimulus	The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus.	got7fsn_ti	cellular glucose import in response to insulin stimulus						jl	2011-12-08T02:44:01Z						biological_process											owl:Class	
GO:0046323	biolink:NamedThing	glucose import	The directed movement of the hexose monosaccharide glucose into a cell or organelle.	got7fsn_ti	glucose uptake											Wikipedia:Glucose_uptake		biological_process											owl:Class	
GO:0042616	biolink:NamedThing	paclitaxel metabolic process	The chemical reactions and pathways involving paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.	got7fsn_ti	paclitaxel metabolism|taxol metabolic process|taxol metabolism													biological_process											owl:Class	
GO:0034734	biolink:NamedThing	transcription factor TFIIIC1 complex	A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0102695	biolink:NamedThing	UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-4733		molecular_function											owl:Class	
GO:0008807	biolink:NamedThing	carboxyvinyl-carboxyphosphonate phosphorylmutase activity	Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2.	got7fsn_ti	1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating)|carboxyphosphonoenolpyruvate phosphonomutase activity|CPEP phosphonomutase activity											RHEA:14045|EC:2.7.8.23|MetaCyc:2.7.8.23-RXN		molecular_function											owl:Class	
GO:0018125	biolink:NamedThing	peptidyl-cysteine methylation	The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine.	got7fsn_ti												RESID:AA0234		biological_process											owl:Class	
GO:0047703	biolink:NamedThing	beta-nitroacrylate reductase activity	Catalysis of the reaction: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH.	got7fsn_ti	b-nitroacrylate reductase activity|3-nitropropanoate:NADP+ oxidoreductase activity											KEGG_REACTION:R03900|MetaCyc:BETA-NITROACRYLATE-REDUCTASE-RXN|RHEA:23892|EC:1.3.1.16		molecular_function											owl:Class	
GO:0072218	biolink:NamedThing	metanephric ascending thin limb development	The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.	got7fsn_ti							mah	2010-03-18T03:34:42Z						biological_process											owl:Class	
GO:0033777	biolink:NamedThing	lithocholate 6beta-hydroxylase activity	Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+).	got7fsn_ti	cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity|lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity|lithocholate 6beta-monooxygenase activity|6beta-hydroxylase activity|CYP3A10											KEGG_REACTION:R07203|MetaCyc:1.14.13.94-RXN|RHEA:18857|EC:1.14.14.138		molecular_function											owl:Class	
GO:0033944	biolink:NamedThing	beta-galactofuranosidase activity	Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.	got7fsn_ti	beta-D-galactofuranosidase activity|exo-beta-galactofuranosidase activity|beta-D-galactofuranoside hydrolase activity|exo-beta-D-galactofuranosidase activity											MetaCyc:3.2.1.146-RXN|EC:3.2.1.146		molecular_function											owl:Class	
GO:0019711	biolink:NamedThing	peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid	The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid.	got7fsn_ti	peptidyl-beta-carboxyaspartic acid synthesis from peptidyl-aspartic acid|peptidyl-beta-carboxyaspartic acid anabolism from peptidyl-aspartic acid|peptidyl-beta-carboxyaspartic acid formation from peptidyl-aspartic acid													biological_process											owl:Class	
GO:0036353	biolink:NamedThing	histone H2A-K119 monoubiquitination	The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms.	got7fsn_ti	histone H2A monoubiquitination (H2A-K119)						bf	2012-09-19T11:52:25Z						biological_process											owl:Class	
GO:1900561	biolink:NamedThing	dehydroaustinol metabolic process	The chemical reactions and pathways involving dehydroaustinol.	got7fsn_ti	dehydroaustinol metabolism						di	2012-05-15T06:27:35Z						biological_process											owl:Class	
GO:0006706	biolink:NamedThing	steroid catabolic process	The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	got7fsn_ti	steroid breakdown|steroid degradation|steroid catabolism													biological_process											owl:Class	
GO:0102664	biolink:NamedThing	indole-3-acetyl-leucine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-leucine  + ATP <=> H+ + indole-3-acetyl-leucine + diphosphoric acid + AMP.	got7fsn_ti												MetaCyc:RXN-2945		molecular_function											owl:Class	
GO:0036298	biolink:NamedThing	recombinational interstrand cross-link repair	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.	got7fsn_ti	recombination-dependent interstrand cross-link repair						bf	2012-08-07T11:11:59Z						biological_process											owl:Class	
GO:0047568	biolink:NamedThing	3-oxo-5-beta-steroid 4-dehydrogenase activity	Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor.	got7fsn_ti	3-oxo-5beta-steroid:(acceptor) delta4-oxidoreductase activity|3-oxo-5beta-steroid 4-dehydrogenase activity|3-oxo-5beta-steroid:acceptor delta4-oxidoreductase activity|delta4-3-ketosteroid 5-beta-reductase activity											RHEA:24172|EC:1.3.99.6|MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:1900805	biolink:NamedThing	brevianamide F biosynthetic process	The chemical reactions and pathways resulting in the formation of brevianamide F.	got7fsn_ti	cyclo-L-tryptophanyl-L-proline biosynthetic process|cyclo-(Trp-Pro) formation|cyclo-(Trp-Pro) biosynthesis|cyclo-L-tryptophanyl-L-proline formation|C16H17N3O2 synthesis|cyclo-L-tryptophanyl-L-proline biosynthesis|cyclo-L-Trp-L-Pro synthesis|L-prolyl-L-tryptophan anhydride biosynthesis|C16H17N3O2 anabolism|cyclo-L-Trp-L-Pro anabolism|tryptophan-proline diketopiperazine anabolism|cyclo-(Trp-Pro) biosynthetic process|cyclo-L-Trp-L-Pro formation|C16H17N3O2 formation|L-prolyl-L-tryptophan anhydride synthesis|L-prolyl-L-tryptophan anhydride formation|C16H17N3O2 biosynthesis|L-prolyl-L-tryptophan anhydride anabolism|brevianamide F formation|L-tryptophyl-L-proline cyclic anhydride formation|L-tryptophyl-L-proline cyclic anhydride anabolism|L-tryptophyl-L-proline cyclic anhydride biosynthetic process|tryptophan-proline diketopiperazine synthesis|cyclo-(Trp-Pro) synthesis|cyclo-L-Trp-L-Pro biosynthesis|cyclo-L-tryptophanyl-L-proline synthesis|tryptophan-proline diketopiperazine biosynthesis|brevianamide F anabolism|tryptophan-proline diketopiperazine biosynthetic process|brevianamide F biosynthesis|cyclo-L-tryptophanyl-L-proline anabolism|L-tryptophyl-L-proline cyclic anhydride synthesis|cyclo-(Trp-Pro) anabolism|cyclo-L-Trp-L-Pro biosynthetic process|L-tryptophyl-L-proline cyclic anhydride biosynthesis|C16H17N3O2 biosynthetic process|brevianamide F synthesis|tryptophan-proline diketopiperazine formation|L-prolyl-L-tryptophan anhydride biosynthetic process						di	2012-06-04T09:52:48Z						biological_process											owl:Class	
GO:0016989	biolink:NamedThing	sigma factor antagonist activity	The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.	got7fsn_ti	anti-sigma factor activity													molecular_function											owl:Class	
GO:0043793	biolink:NamedThing	beta-ribofuranosylaminobenzene 5'-phosphate synthase activity	Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate.	got7fsn_ti	beta-RFAP synthase activity											MetaCyc:RXN-8124		molecular_function											owl:Class	
GO:0035491	biolink:NamedThing	positive regulation of leukotriene production involved in inflammatory response	Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.	got7fsn_ti							bf	2010-04-26T10:50:14Z						biological_process											owl:Class	
GO:0070279	biolink:NamedThing	vitamin B6 binding	Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0044219	biolink:NamedThing	host cell plasmodesma	A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.	got7fsn_ti							jl	2009-11-12T02:50:52Z						cellular_component											owl:Class	
GO:1900770	biolink:NamedThing	fumitremorgin B metabolic process	The chemical reactions and pathways involving fumitremorgin B.	got7fsn_ti	fumitremorgin B metabolism|Lanosulin metabolic process|Lanosulin metabolism						di	2012-06-04T09:25:18Z						biological_process											owl:Class	
GO:1990407	biolink:NamedThing	calcitonin gene-related peptide binding	Binding to calcitonin gene-related peptide (CGRP).	got7fsn_ti	CGRP polypeptide binding|calcitonin-gene-related polypeptide binding|calcitonin-gene-related peptide binding				An example of this is CALCRL in human (Q16602) in PMID:10882736 (inferred from direct assay/mutant phenotype/etc.).		bhm	2014-07-02T14:22:06Z						molecular_function											owl:Class	
GO:0033808	biolink:NamedThing	6'-deoxychalcone synthase activity	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O.	got7fsn_ti	malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing) activity											EC:2.3.1.170|RHEA:10584|MetaCyc:RXN-3142		molecular_function											owl:Class	
GO:0021959	biolink:NamedThing	cuneatus tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.	got7fsn_ti	tract of Burdach morphogenesis													biological_process											owl:Class	
GO:0075513	biolink:NamedThing	caveolin-mediated endocytosis of virus by host cell	Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus.	got7fsn_ti	viral entry into host cell via caveolae-mediated endocytosis|viral entry into host cell via caveolin-mediated endocytosis|viral penetration via caveolae-mediated endocytosis followed by endosome disruption						jl	2011-07-27T02:40:04Z				VZ:976		biological_process											owl:Class	
GO:0050012	biolink:NamedThing	juglone 3-hydroxylase activity	Catalysis of the reaction: 2 juglone + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H+.	got7fsn_ti	juglone 3-monooxygenase activity|5-hydroxy-1,4-naphthoquinone,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating)|juglone hydroxylase activity|naphthoquinone hydroxylase activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.14.99.27.							KEGG_REACTION:R04327|EC:1.17.3.4|MetaCyc:JUGLONE-3-MONOOXYGENASE-RXN|RHEA:18745		molecular_function											owl:Class	
GO:1903502	biolink:NamedThing	translation repressor complex	A protein complex which is capable of translation repressor activity.	got7fsn_ti					An example of this is Eif4e in drome (P48598) in PMID:14723848 (inferred from physical interaction).		bhm	2014-09-30T12:44:27Z						cellular_component											owl:Class	
GO:0033789	biolink:NamedThing	phenylacetyl-CoA dehydrogenase activity	Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.	got7fsn_ti	phenylacetyl-CoA:acceptor oxidoreductase activity|phenylacetyl-CoA:quinone oxidoreductase activity											MetaCyc:1.17.5.1-RXN|KEGG_REACTION:R07222|RHEA:15705|EC:1.17.5.1		molecular_function											owl:Class	
GO:0102054	biolink:NamedThing	maleylpyruvate hydrolase activity	Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O <=> H+ + maleate(2-) + pyruvate.	got7fsn_ti												MetaCyc:RXN-10447|RHEA:47956		molecular_function											owl:Class	
GO:0106276	biolink:NamedThing	biliberdin reductase NAD+ activity	Catalysis of the reaction: bilirubin + NAD+ = biliverdin + NADH+ H+.	got7fsn_ti							hjd	2020-07-02T01:48:07Z				RHEA:15797|EC:1.3.1.24		molecular_function											owl:Class	
GO:0004074	biolink:NamedThing	biliverdin reductase (NAD(P)+) activity	Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.	got7fsn_ti	bilirubin:NAD(P)+ oxidoreductase activity											Reactome:R-HSA-189384|MetaCyc:BILIVERDIN-REDUCTASE-RXN|EC:1.3.1.24		molecular_function											owl:Class	
GO:0050206	biolink:NamedThing	oximinotransferase activity	Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate.	got7fsn_ti	oximinotransaminase activity|transoximinase activity|transoximase activity|oximase activity|pyruvate-acetone oximinotransferase activity										GO:0016770	EC:2.6.3.1|MetaCyc:OXIMINOTRANSFERASE-RXN|RHEA:11624|KEGG_REACTION:R03796		molecular_function											owl:Class	
GO:0034610	biolink:NamedThing	oligodeoxyribonucleotidase activity	Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates.	got7fsn_ti	DNA oligonucleotidase activity													molecular_function											owl:Class	
GO:0030768	biolink:NamedThing	16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity	Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H(+).	got7fsn_ti	NMT activity|S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity|3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity|16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase activity|S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity											EC:2.1.1.99|RHEA:11336|MetaCyc:2.1.1.99-RXN|KEGG_REACTION:R04013		molecular_function											owl:Class	
GO:0018600	biolink:NamedThing	alpha-pinene dehydrogenase activity	Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol.	got7fsn_ti												UM-BBD_reactionID:r0709|EC:1.14.-.-		molecular_function											owl:Class	
GO:0015452	biolink:NamedThing	methyl transfer-driven active transmembrane transporter activity	Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.	got7fsn_ti	Methyltransfer-driven transporters											TC:3.C		molecular_function											owl:Class	
GO:0097666	biolink:NamedThing	SCF-Met30/Pof1 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).	got7fsn_ti							pr	2014-10-06T10:27:49Z						cellular_component											owl:Class	
GO:0090669	biolink:NamedThing	telomerase RNA stabilization	Prevention of degradation of telomerase RNA (TERC) molecules.	got7fsn_ti	TERC stabilization						tb	2015-12-17T14:01:11Z						biological_process											owl:Class	
GO:0035761	biolink:NamedThing	dorsal motor nucleus of vagus nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.	got7fsn_ti							bf	2011-03-29T02:45:50Z						biological_process											owl:Class	
GO:0007616	biolink:NamedThing	long-term memory	The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.	got7fsn_ti												Wikipedia:Long-term_memory		biological_process											owl:Class	
GO:1990966	biolink:NamedThing	ATP generation from poly-ADP-D-ribose	The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.	got7fsn_ti							sp	2016-06-16T09:41:35Z						biological_process											owl:Class	
GO:0050634	biolink:NamedThing	phloroisovalerophenone synthase activity	Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.	got7fsn_ti	valerophenone synthase activity|3-methyl-1-(trihydroxyphenyl)butan-1-one synthase activity|isovaleryl-CoA:malonyl-CoA acyltransferase activity											RHEA:23572|MetaCyc:2.3.1.156-RXN|EC:2.3.1.156		molecular_function											owl:Class	
GO:0099155	biolink:NamedThing	synaptic transmission, noradrenergic	The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	got7fsn_ti	noradrenergic synaptic transmission						dos	2017-07-05T14:36:55Z						biological_process											owl:Class	
GO:0140459	biolink:NamedThing	response to Gram-positive bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19278					pg	2020-04-30T07:33:34Z						biological_process											owl:Class	
GO:0032498	biolink:NamedThing	detection of muramyl dipeptide	The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan.	got7fsn_ti														biological_process											owl:Class	
GO:0032495	biolink:NamedThing	response to muramyl dipeptide	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.	got7fsn_ti														biological_process											owl:Class	
GO:0003944	biolink:NamedThing	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity	Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.	got7fsn_ti	alpha-N-acetylglucosaminyl phosphodiesterase activity|lysosomal alpha-N-acetylglucosaminidase activity|2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase activity|phosphodiester glycosidase activity|glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase activity|alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase activity											EC:3.1.4.45|RHEA:24372|MetaCyc:3.1.4.45-RXN		molecular_function											owl:Class	
GO:0047513	biolink:NamedThing	1,2-alpha-L-fucosidase activity	Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside.	got7fsn_ti	2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase activity|alpha-(1->2)-L-fucosidase activity|almond emulsin fucosidase activity|almond emulsin fucosidase II activity											MetaCyc:12-ALPHA-L-FUCOSIDASE-RXN|EC:3.2.1.63|RHEA:10816		molecular_function											owl:Class	
GO:0097474	biolink:NamedThing	retinal cone cell apoptotic process	Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.	got7fsn_ti	cone photoreceptor apoptotic process						pr	2013-03-21T09:46:22Z						biological_process											owl:Class	
GO:0051980	biolink:NamedThing	iron-nicotianamine transmembrane transporter activity	Enables the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other.	got7fsn_ti	Fe-NA chelate transporter activity													molecular_function											owl:Class	
GO:0070222	biolink:NamedThing	sulfide oxidation, using sulfide dehydrogenase	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase.	got7fsn_ti	sulphide oxidation, using sulfide dehydrogenase											MetaCyc:PWY-5274		biological_process											owl:Class	
GO:0019908	biolink:NamedThing	nuclear cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent protein kinase (CDK) complex found in the nucleus.	got7fsn_ti	CDK holoenzyme													cellular_component											owl:Class	
GO:0018012	biolink:NamedThing	N-terminal peptidyl-alanine trimethylation	The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.	got7fsn_ti												RESID:AA0062		biological_process											owl:Class	
GO:0016938	biolink:NamedThing	kinesin I complex	A complex of two kinesin heavy chains and two kinesin light chains.	got7fsn_ti														cellular_component											owl:Class	
GO:1990097	biolink:NamedThing	SeqA-DNA complex	A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle.	got7fsn_ti	SeqA-hemimethylated DNA complex|SeqA-dsDNA complex|SeqA-hemimethylation dsDNA complex						bhm	2013-05-13T11:18:11Z						cellular_component											owl:Class	
GO:0047469	biolink:NamedThing	4-carboxymethyl-4-methylbutenolide mutase activity	Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide.	got7fsn_ti	4-methyl-3-enelactone methyl isomerase activity|4-methyl-2-enelactone isomerase activity|4-methylmuconolactone methylisomerase activity|4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase activity|4-methyl-2-enelactone methyl-isomerase activity											EC:5.4.99.14|MetaCyc:5.4.99.14-RXN|KEGG_REACTION:R04510|RHEA:19237		molecular_function											owl:Class	
GO:0050017	biolink:NamedThing	L-3-cyanoalanine synthase activity	Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine.	got7fsn_ti	beta-cyano-L-alanine synthase activity|beta-cyanoalanine synthase activity|L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)|L-cysteine hydrogen-sulfide-lyase (adding HCN)|beta-cyanoalanine synthetase activity											RHEA:17821|MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN|EC:4.4.1.9		molecular_function											owl:Class	
GO:0033703	biolink:NamedThing	3beta-hydroxy-5beta-steroid dehydrogenase activity	Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH.	got7fsn_ti	3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity|3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity|3beta-hydroxysteroid 5beta-oxidoreductase activity											EC:1.1.1.277|MetaCyc:1.1.1.277-RXN|KEGG_REACTION:R06166|RHEA:22944		molecular_function											owl:Class	
GO:0072747	biolink:NamedThing	cellular response to chloramphenicol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.	got7fsn_ti							mah	2012-08-31T12:33:30Z						biological_process											owl:Class	
GO:0050037	biolink:NamedThing	L-xylose 1-dehydrogenase activity	Catalysis of the reaction: aldehydo-L-xylose + NADP(+) = L-xylono-1,4-lactone + H(+) + NADPH.	got7fsn_ti	L-xylose dehydrogenase activity|NADPH-xylose reductase activity|L-xylose:NADP+ 1-oxidoreductase activity											KEGG_REACTION:R03586|EC:1.1.1.113|RHEA:15789|MetaCyc:L-XYLOSE-1-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0043807	biolink:NamedThing	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin.	got7fsn_ti	VOR|3-methyl-2-oxobutanoate synthase (ferredoxin) activity|2-oxoisovalerate ferredoxin reductase activity|2-ketoisovalerate ferredoxin reductase activity|keto-valine-ferredoxin oxidoreductase activity|ketoisovalerate oxidoreductase activity|branched-chain oxo acid ferredoxin reductase activity|3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylpropanoylating)|ketoisovalerate ferredoxin reductase activity|branched-chain ketoacid ferredoxin reductase activity											EC:1.2.7.7|RHEA:11712|MetaCyc:1.2.7.7-RXN		molecular_function											owl:Class	
GO:0004019	biolink:NamedThing	adenylosuccinate synthase activity	Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.	got7fsn_ti	adenylosuccinate synthetase activity|IMP--aspartate ligase activity|succino-AMP synthetase activity|succinoadenylic kinosynthetase activity|IMP:L-aspartate ligase (GDP-forming)											KEGG_REACTION:R01135|Reactome:R-HSA-111524|EC:6.3.4.4|RHEA:15753|MetaCyc:ADENYLOSUCCINATE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0050259	biolink:NamedThing	ribose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: H(2)O + NADP(+) + ribofuranose = D-ribonate + 2 H(+) + NADPH.	got7fsn_ti	D-ribose dehydrogenase (NADP+)|D-ribose:NADP+ 1-oxidoreductase activity|NADP-pentose-dehydrogenase activity											EC:1.1.1.115|KEGG_REACTION:R01079|MetaCyc:RIBOSE-1-DEHYDROGENASE-NADP+-RXN|RHEA:11676		molecular_function											owl:Class	
GO:0047981	biolink:NamedThing	histidine N-acetyltransferase activity	Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+).	got7fsn_ti	acetyl-CoA:L-histidine N-acetyltransferase activity|acetylhistidine synthetase activity|histidine acetyltransferase activity											KEGG_REACTION:R01160|EC:2.3.1.33|MetaCyc:HISTIDINE-N-ACETYLTRANSFERASE-RXN|RHEA:24596		molecular_function											owl:Class	
GO:0140630	biolink:NamedThing	all-trans-phytoene synthase activity	Catalysis of the reaction: 2 geranylgeranyl diphosphate -> all-trans-phytoene + 2 diphosphate.	got7fsn_ti	phytoene synthase activity	https://github.com/geneontology/go-ontology/issues/21165					pg	2021-03-25T18:04:01Z						molecular_function											owl:Class	
GO:0035035	biolink:NamedThing	histone acetyltransferase binding	Binding to an histone acetyltransferase.	got7fsn_ti	histone acetylase binding													molecular_function											owl:Class	
GO:0030623	biolink:NamedThing	U5 snRNA binding	Binding to a U5 small nuclear RNA (U5 snRNA).	got7fsn_ti														molecular_function											owl:Class	
GO:0047161	biolink:NamedThing	tartronate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate.	got7fsn_ti	hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase activity|sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase activity|tartronate sinapoyltransferase activity											EC:2.3.1.106|MetaCyc:2.3.1.106-RXN|KEGG_REACTION:R03965|RHEA:10952		molecular_function											owl:Class	
GO:1990456	biolink:NamedThing	mitochondrion-endoplasmic reticulum membrane tethering	The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.	got7fsn_ti	mitochondrion-ER attachment|mitochondrion-endoplasmic reticulum tethering|mitochondrion-ER membrane tethering|mitochondrion-endoplasmic reticulum attachment|mitochondrion-ER tethering						mcc	2014-08-14T13:32:30Z						biological_process											owl:Class	
GO:0052818	biolink:NamedThing	heteroglycan 3-alpha-mannosyltransferase activity	Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP.	got7fsn_ti	GDP-mannose:heteroglycan 3-alpha-D-mannosyltransferase activity|GDP mannose 3-alpha-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan 3-alpha-mannosyltransferase activity|heteropolysaccharide 3-alpha-mannosyltransferase activity						ai	2011-10-27T12:36:10Z				MetaCyc:RXN-7992|KEGG_REACTION:R03769|EC:2.4.1.48		molecular_function											owl:Class	
GO:0102961	biolink:NamedThing	4,4'-diapophytofluene desaturase activity	Catalysis of the reaction: all-trans-4,4'-diapophytofluene + FAD + H+ = all-trans-4,4'-diapo-zeta-carotene + FADH2.	got7fsn_ti												MetaCyc:RXN-9304|RHEA:31399		molecular_function											owl:Class	
GO:0032398	biolink:NamedThing	MHC class Ib protein complex	A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.	got7fsn_ti														cellular_component											owl:Class	
GO:0006579	biolink:NamedThing	amino-acid betaine catabolic process	The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid.	got7fsn_ti	betaine degradation|betaine catabolic process|betaine breakdown|betaine catabolism													biological_process											owl:Class	
GO:0044179	biolink:NamedThing	hemolysis in other organism	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.	got7fsn_ti	hemolysis of erythrocytes in other organism|hemolysis of red blood cells in other organism|hemolysis of cells in other organism|hemolysis of RBCs in other organism						jl	2009-09-04T03:36:00Z						biological_process											owl:Class	
GO:0031824	biolink:NamedThing	type 1E serotonin receptor binding	Binding to a type 1E serotonin receptor.	got7fsn_ti	type 1E serotonin receptor ligand|5-hydroxytryptamine 1E receptor binding													molecular_function											owl:Class	
GO:0098816	biolink:NamedThing	mini excitatory postsynaptic potential	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.	got7fsn_ti														biological_process											owl:Class	
GO:0008666	biolink:NamedThing	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity	Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA.	got7fsn_ti	tetrahydropicolinate succinylase activity|succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase activity|tetrahydrodipicolinate N-succinyltransferase activity|succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity|tetrahydrodipicolinate succinyltransferase activity|tetrahydrodipicolinate succinylase activity|THDP N-succinyltransferase activity|succinyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity											KEGG_REACTION:R04365|MetaCyc:TETHYDPICSUCC-RXN|RHEA:17325|EC:2.3.1.117		molecular_function											owl:Class	
GO:0008307	biolink:NamedThing	structural constituent of muscle	The action of a molecule that contributes to the structural integrity of a muscle fiber.	got7fsn_ti														molecular_function											owl:Class	
GO:0097544	biolink:NamedThing	ciliary shaft	The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space.	got7fsn_ti	cilium shaft|flagellar shaft|cilial shaft|flagellum shaft				Note that 'ciliary shaft' is sparingly used in the literature to denote the projecting part of the cilium; many authors would refer to the axoneme instead. However, the definition of GO:0005930 'axoneme' is rather stringent, and the localization of many ciliary proteins would not fit that definition. Also, note that cilia and eukaryotic flagella are deemed to be equivalent.		pr	2013-12-12T11:17:30Z						cellular_component											owl:Class	
GO:0102378	biolink:NamedThing	steviolmonoside glucosyltransferase activity	Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13512		molecular_function											owl:Class	
GO:0050440	biolink:NamedThing	2-methylcitrate synthase activity	Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+).	got7fsn_ti	MCS activity|methylcitrate synthetase activity|2-methylcitrate oxaloacetate-lyase activity|methylcitrate synthase activity|propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)											EC:2.3.3.5|RHEA:23780|KEGG_REACTION:R00931|MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0035134	biolink:NamedThing	post-embryonic dorsal fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.	got7fsn_ti														biological_process											owl:Class	
GO:0102318	biolink:NamedThing	2-deoxystreptamine glucosyltransferase activity	Catalysis of the reaction: 2-deoxystreptamine + UDP-alpha-D-glucose <=> 2'-deamino-2'-hydroxyparomamine + UDP(3-) + H+.	got7fsn_ti												RHEA:34063|MetaCyc:RXN-13121|EC:2.4.1.284		molecular_function											owl:Class	
GO:0004960	biolink:NamedThing	thromboxane receptor activity	Combining with a thromboxane (TXA) to initiate a change in cell activity.	got7fsn_ti	TXA receptor activity													molecular_function											owl:Class	
GO:0062182	biolink:NamedThing	all-trans retinoic acid 4-hydrolase activity	Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							dph	2019-11-26T18:36:06Z				RHEA:51492		molecular_function											owl:Class	
GO:0017058	biolink:NamedThing	FH1 domain binding	Binding to a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.	got7fsn_ti														molecular_function											owl:Class	
GO:0021968	biolink:NamedThing	corticospinal neuron axon guidance through the internal capsule	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues.	got7fsn_ti	corticospinal neuron axon pathfinding through the internal capsule													biological_process											owl:Class	
GO:0060842	biolink:NamedThing	arterial endothelial cell differentiation	The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.	got7fsn_ti							dph	2009-08-12T10:41:34Z						biological_process											owl:Class	
GO:0036519	biolink:NamedThing	chemorepulsion of serotonergic neuron axon	The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.	got7fsn_ti	chemorepulsion of 5-HT axon|chemorepulsion of serotonergic axon						bf	2015-12-17T11:31:16Z						biological_process											owl:Class	
GO:0033460	biolink:NamedThing	GAG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GAG codon.	got7fsn_ti	glutamic acid tRNA				Note that in the standard genetic code, GAG codes for glutamic acid.									molecular_function											owl:Class	
GO:0047117	biolink:NamedThing	enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+.	got7fsn_ti	enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|enoyl-ACP reductase (NADPH, A-specific) activity|enoyl-[acyl-carrier protein] reductase (NADPH, A-specific) activity|enoyl-acyl-carrier-protein reductase (NADPH, A-specific)|enoyl-ACp reductase activity|acyl-acyl-carrier-protein:NADP+ oxidoreductase (A-specific)											EC:1.3.1.39|MetaCyc:1.3.1.39-RXN		molecular_function											owl:Class	
GO:0043803	biolink:NamedThing	hydroxyneurosporene-O-methyltransferase activity	Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + spheroidene.	got7fsn_ti	1-hydroxycarotenoid O-methylase|1-HO-carotenoid methylase|1-hydroxycarotenoid methylase|demethylspheroidene O-methyltransferase											EC:2.1.1.210|RHEA:30903		molecular_function											owl:Class	
GO:0034503	biolink:NamedThing	protein localization to nucleolar rDNA repeats	Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus.	got7fsn_ti	protein localisation to nucleolar rDNA repeats|condensin localization to nucleolar rDNA repeats													biological_process											owl:Class	
GO:0043768	biolink:NamedThing	S-ribosylhomocysteine lyase activity	Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine.	got7fsn_ti	S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming]|S-ribosylhomocysteinase activity|LuxS|ribosylhomocysteinase activity										GO:0019138	KEGG_REACTION:R01291|EC:4.4.1.21|RHEA:17753|MetaCyc:RIBOSYLHOMOCYSTEINASE-RXN		molecular_function											owl:Class	
GO:0075529	biolink:NamedThing	establishment of latency as a circular episome	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure.	got7fsn_ti	establishment of circular plasmid latency|establishment of latency as a circular plasmid						jl	2011-08-04T03:08:17Z						biological_process											owl:Class	
GO:0047896	biolink:NamedThing	formaldehyde transketolase activity	Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone.	got7fsn_ti	glycerone synthase activity|D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase activity|dihydroxyacetone synthase activity|DHAS activity											EC:2.2.1.3|RHEA:24264|MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN		molecular_function											owl:Class	
GO:0120283	biolink:NamedThing	protein serine/threonine kinase binding	Binding to a protein serine/threonine kinase.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15218					krc	2020-11-17T16:26:36Z						molecular_function											owl:Class	
GO:0001818	biolink:NamedThing	negative regulation of cytokine production	Any process that stops, prevents, or reduces the rate of production of a cytokine.	got7fsn_ti	downregulation of cytokine biosynthetic process|down-regulation of cytokine biosynthetic process|negative regulation of cytokine anabolism|negative regulation of cytokine biosynthetic process|inhibition of cytokine biosynthetic process|down-regulation of cytokine production|down regulation of cytokine production|negative regulation of cytokine secretion|down regulation of cytokine biosynthetic process|negative regulation of cytokine synthesis|negative regulation of cytokine formation|downregulation of cytokine production|inhibition of cytokine production|negative regulation of cytokine biosynthesis										GO:0050710|GO:0042036			biological_process											owl:Class	
GO:0042048	biolink:NamedThing	olfactory behavior	The behavior of an organism in response to an odor.	got7fsn_ti	behavioural response to odour|olfactory behaviour|behavioral response to smell|behavioural response to scent|behavioral response to scent|behavioural response to smell													biological_process											owl:Class	
GO:0039658	biolink:NamedThing	TBK1-IKKE-DDX3 complex	A protein complex containing TBK1 (TANK-binding kinase 1), IKBKE (I-Kappa-B kinase epsilon/IKKE/IKK-epsilon) and the DEAD box family RNA helicase DDX3.	got7fsn_ti	TBK1-IKBKE-DDX3 complex						bf	2013-07-03T16:59:27Z						cellular_component											owl:Class	
GO:0019500	biolink:NamedThing	cyanide catabolic process	The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.	got7fsn_ti	cyanide degradation|cyanide breakdown|cyanide catabolism											MetaCyc:P401-PWY		biological_process											owl:Class	
GO:0036223	biolink:NamedThing	cellular response to adenine starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine.	got7fsn_ti	cellular response to adenine deprivation						bf	2012-05-09T02:26:52Z						biological_process											owl:Class	
GO:0060763	biolink:NamedThing	mammary duct terminal end bud growth	The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.	got7fsn_ti							dph	2009-07-06T07:33:50Z						biological_process											owl:Class	
GO:0106245	biolink:NamedThing	L-serine-phosphatidylethanolamine phosphatidyltransferase activity	Catalysis of the reaction: L-1-phosphatidylethanolamine + L-serine <=> L-1-phosphatidylserine + ethanolamine.	got7fsn_ti							hjd	2020-01-22T15:27:57Z				RHEA:27606|EC:2.7.8.29		molecular_function											owl:Class	
GO:0050273	biolink:NamedThing	S-succinylglutathione hydrolase activity	Catalysis of the reaction: S-succinylglutathione + H(2)O = glutathione + H(+) + succinate.	got7fsn_ti												MetaCyc:S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN|EC:3.1.2.13|KEGG_REACTION:R00499|RHEA:16713		molecular_function											owl:Class	
GO:1900794	biolink:NamedThing	terrequinone A metabolic process	The chemical reactions and pathways involving terrequinone A.	got7fsn_ti	terrequinone A metabolism						di	2012-06-04T09:45:20Z						biological_process											owl:Class	
GO:1990208	biolink:NamedThing	positive regulation by symbiont of RNA levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							ml	2013-10-08T13:31:41Z						biological_process											owl:Class	
GO:0031278	biolink:NamedThing	alpha-1,2-galactosyltransferase activity	Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage.	got7fsn_ti														molecular_function											owl:Class	
GO:1990714	biolink:NamedThing	hydroxyproline O-galactosyltransferase activity	Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone.	got7fsn_ti	HPGT						tb	2015-03-26T23:22:09Z						molecular_function											owl:Class	
GO:0047719	biolink:NamedThing	indole 2,3-dioxygenase activity	Catalysis of the reaction: indole + O(2) = 2-formamidobenzaldehyde.	got7fsn_ti	indole:O2 oxidoreductase activity|indole oxidase activity|indole-oxygen 2,3-oxidoreductase (decyclizing)|indole:oxygen 2,3-oxidoreductase (decyclizing)|IDO											MetaCyc:INDOLE-23-DIOXYGENASE-RXN|KEGG_REACTION:R02338|RHEA:11212|EC:1.13.11.17		molecular_function											owl:Class	
GO:0052622	biolink:NamedThing	ATP dimethylallyltransferase activity	Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate.	got7fsn_ti	dimethylallyl-diphosphate:ATP dimethylallyltransferase activity|ATP isopentenyltransferase activity|2-isopentenyl-diphosphate:ATP 2-isopentenyltransferase activity|2-isopentenyl-diphosphate:ATP delta2-isopentenyltransferase activity						ai	2010-08-26T10:45:38Z				MetaCyc:RXN-4303|EC:2.5.1.-|KEGG_REACTION:R08052		molecular_function											owl:Class	
GO:0008667	biolink:NamedThing	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity	Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH.	got7fsn_ti	2,3-DHB dehydrogenase activity|2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase activity											KEGG_REACTION:R01505|EC:1.3.1.28|RHEA:23824|MetaCyc:DHBDEHYD-RXN		molecular_function											owl:Class	
GO:0090397	biolink:NamedThing	stigma papilla	A plant cell papilla that is part of a stigma papilla cell.	got7fsn_ti					Part of stigma papilla cell (PO:0025168).		tb	2010-12-15T03:26:20Z						cellular_component											owl:Class	
GO:0060729	biolink:NamedThing	intestinal epithelial structure maintenance	A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.	got7fsn_ti	maintenance of intestinal epithelium|epithelial structure maintenance of intestine						dph	2009-06-12T01:44:52Z						biological_process											owl:Class	
GO:0098616	biolink:NamedThing	selenate adenylyltransferase (ATP) activity	Catalysis of the reaction: ATP + H2SeO4 => diphosphate + adenylylselenate.	got7fsn_ti												Reactome:R-HSA-2408525		molecular_function											owl:Class	
GO:0036218	biolink:NamedThing	dTTP diphosphatase activity	Catalysis of the reaction: dTTP + H2O = dTMP + diphosphate.	got7fsn_ti							bf	2012-05-08T01:47:59Z				EC:3.6.1.9|RHEA:28534|MetaCyc:RXN0-5107		molecular_function											owl:Class	
GO:0036386	biolink:NamedThing	bacterial nucleoid DNA packaging	Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling.	got7fsn_ti	prokaryotic DNA condensation|nucleoid compaction|chromosomal compaction						bf	2013-05-30T10:41:08Z						biological_process											owl:Class	
GO:0035861	biolink:NamedThing	site of double-strand break	A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.	got7fsn_ti	IRIF|DNA damage focus|ionizing radiation-induced foci|site of DSB|DNA damage foci						bf	2011-05-17T03:04:42Z						cellular_component											owl:Class	
GO:0043826	biolink:NamedThing	sulfur oxygenase reductase activity	Catalysis of the reaction: 5 sulfur + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide + 9 H+.	got7fsn_ti	sulphur oxygenase reductase activity|SOR											MetaCyc:RXN-8226		molecular_function											owl:Class	
GO:0072701	biolink:NamedThing	cellular response to bismuth	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.	got7fsn_ti	cellular response to bismuth ion						mah	2012-04-11T02:56:42Z						biological_process											owl:Class	
GO:0030760	biolink:NamedThing	pyridine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine.	got7fsn_ti	pyridine methyltransferase activity|S-adenosyl-L-methionine:pyridine N-methyltransferase activity											KEGG_REACTION:R02862|EC:2.1.1.87|MetaCyc:PYRIDINE-N-METHYLTRANSFERASE-RXN|Reactome:R-HSA-175987|RHEA:16893		molecular_function											owl:Class	
GO:0047113	biolink:NamedThing	aldehyde dehydrogenase (quinone) activity	Catalysis of the reaction: an aldehyde + a quinone + H2O = a carboxylate + a quinol.	got7fsn_ti	aldehyde:(pyrroloquinoline-quinone) oxidoreductase activity|aldehyde dehydrogenase (acceptor) activity|aldehyde dehydrogenase (pyrroloquinoline-quinone)											MetaCyc:1.2.99.3-RXN|RHEA:13881|EC:1.2.5.2		molecular_function											owl:Class	
GO:0098982	biolink:NamedThing	GABA-ergic synapse	A synapse that uses GABA as a neurotransmitter.  These synapses are typically inhibitory.	got7fsn_ti														cellular_component											owl:Class	
GO:0070214	biolink:NamedThing	CSK-GAP-A.p62 complex	A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.	got7fsn_ti					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0044536	biolink:NamedThing	envenomation resulting in depletion of circulating fibrinogen in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism.	got7fsn_ti	envenomation resulting in negative regulation of circulating fibrinogen in other organism						jl	2012-03-21T02:56:49Z						biological_process											owl:Class	
GO:0003176	biolink:NamedThing	aortic valve development	The progression of the aortic valve over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-08T11:18:55Z						biological_process											owl:Class	
GO:0102045	biolink:NamedThing	3-chlorobenzoate-3,4-oxygenase activity	Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-10422		molecular_function											owl:Class	
GO:0050086	biolink:NamedThing	mannitol 2-dehydrogenase activity	Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.	got7fsn_ti	D-mannitol dehydrogenase activity|D-mannitol:NAD+ 2-oxidoreductase activity											MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN|EC:1.1.1.67|RHEA:12084		molecular_function											owl:Class	
GO:0061275	biolink:NamedThing	mesonephric proximal tubule development	The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.	got7fsn_ti							dph	2010-09-02T01:08:05Z						biological_process											owl:Class	
GO:0071203	biolink:NamedThing	WASH complex	A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.	got7fsn_ti							mah	2009-11-25T11:01:33Z						cellular_component											owl:Class	
GO:0102910	biolink:NamedThing	dirigent protein activity	Catalysis of the reaction: 2 H+ + 2 coniferol + O2 <=> (+)-pinoresinol + 2 H2O.	got7fsn_ti												MetaCyc:RXN-8677		molecular_function											owl:Class	
GO:0008140	biolink:NamedThing	cAMP response element binding protein binding	Binding to a cAMP response element binding protein (a CREB protein).	got7fsn_ti	3',5' cAMP response element binding protein binding|adenosine 3',5'-cyclophosphate response element binding protein binding|cyclic AMP response element binding protein binding|CREB binding|3',5'-cAMP response element binding protein binding|CBP													molecular_function											owl:Class	
GO:0102411	biolink:NamedThing	quercetin-3,4'-O-glucosyltransferase activity	Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-).	got7fsn_ti												MetaCyc:RXN-13766		molecular_function											owl:Class	
GO:0016254	biolink:NamedThing	preassembly of GPI anchor in ER membrane	The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane.	got7fsn_ti	preassembly of GPI anchor in endoplasmic reticulum membrane													biological_process											owl:Class	
GO:0006650	biolink:NamedThing	glycerophospholipid metabolic process	The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.	got7fsn_ti	phosphoglyceride metabolism|alpha-glycerophosphate pathway|phosphoglyceride metabolic process|glycerophospholipid metabolism										GO:0006652			biological_process											owl:Class	
GO:0047409	biolink:NamedThing	alkenylglycerophosphoethanolamine hydrolase activity	Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde.	got7fsn_ti	1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase activity											RHEA:16905|EC:3.3.2.5|MetaCyc:3.3.2.5-RXN		molecular_function											owl:Class	
GO:0019806	biolink:NamedThing	bromide peroxidase activity	Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.	got7fsn_ti	bromoperoxidase activity											EC:1.11.1.18		molecular_function											owl:Class	
GO:0099525	biolink:NamedThing	presynaptic dense core vesicle exocytosis	The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.	got7fsn_ti														biological_process											owl:Class	
GO:0001608	biolink:NamedThing	G protein-coupled nucleotide receptor activity	Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	nucleotide receptor activity, G-protein coupled|nucleotide receptor activity, G protein coupled|G protein coupled nucleotide receptor activity|G-protein coupled nucleotide receptor activity													molecular_function											owl:Class	
GO:0004493	biolink:NamedThing	methylmalonyl-CoA epimerase activity	Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA.	got7fsn_ti	methylmalonyl-CoA racemase activity|methylmalonyl-CoA 2-epimerase activity|2-methyl-3-oxopropanoyl-CoA 2-epimerase activity|methylmalonyl coenzyme A racemase activity|DL-methylmalonyl-CoA racemase activity											RHEA:20553|MetaCyc:METHYLMALONYL-COA-EPIM-RXN|Reactome:R-HSA-71020|KEGG_REACTION:R02765|EC:5.1.99.1		molecular_function											owl:Class	
GO:0030240	biolink:NamedThing	skeletal muscle thin filament assembly	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.	got7fsn_ti														biological_process											owl:Class	
GO:0090683	biolink:NamedThing	GPCR sweet taste receptor activity	A G protein-coupled receptor activity that is responsible for the sense of sweet taste.	got7fsn_ti	G-protein coupled receptor sweet taste receptor activity						tb	2016-05-20T15:49:18Z						molecular_function											owl:Class	
GO:0102917	biolink:NamedThing	(S)-reticuline 7-O-methyltransferase activity	Catalysis of the reaction: (S)-reticulinium(1+) + S-adenosyl-L-methionine  <=> H+ + laudanine(1+) + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:10444|EC:2.1.1.291|MetaCyc:RXN-8700		molecular_function											owl:Class	
GO:0052798	biolink:NamedThing	beta-galactoside alpha-2,3-sialyltransferase activity	Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor.	got7fsn_ti	trans-sialidase activity													molecular_function											owl:Class	
GO:0043406	biolink:NamedThing	positive regulation of MAP kinase activity	Any process that activates or increases the frequency, rate or extent of MAP kinase activity.	got7fsn_ti	upregulation of MAPK activity|positive regulation of mitogen-activated protein kinase activity|positive regulation of mitogen activated protein kinase activity|up-regulation of MAPK activity|up regulation of MAPK activity|stimulation of MAPK activity													biological_process											owl:Class	
GO:0048258	biolink:NamedThing	3-ketoglucose-reductase activity	Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose.	got7fsn_ti												MetaCyc:KETOGLUCOSE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0043824	biolink:NamedThing	succinylglutamate-semialdehyde dehydrogenase activity	Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH.	got7fsn_ti	N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase activity|AruD|N-succinylglutamate 5-semialdehyde dehydrogenase activity|succinyl glutamate-semialdehyde dehydrogenase activity|AstD|SGSD|succinylglutamic semialdehyde dehydrogenase activity											RHEA:10812|EC:1.2.1.71|KEGG_REACTION:R05049|MetaCyc:SUCCGLUALDDEHYD-RXN		molecular_function											owl:Class	
GO:0033066	biolink:NamedThing	Rad51B-Rad51C complex	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof.	got7fsn_ti	BC complex													cellular_component											owl:Class	
GO:0072651	biolink:NamedThing	interferon-tau production	The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IFN-tau secretion|IFN-tau production|interferon-tau secretion|IFNT production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072652			biological_process											owl:Class	
GO:0102470	biolink:NamedThing	6C-naringenin dibenzoylmethane tautomer glucosyltransferase activity	Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 6C-glucosyl-2-hydroxynaringenin + UDP + H+.	got7fsn_ti												MetaCyc:RXN-14075		molecular_function											owl:Class	
GO:0032364	biolink:NamedThing	oxygen homeostasis	A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0009012	biolink:NamedThing	aminoglycoside 3''-adenylyltransferase activity	Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H(+).	got7fsn_ti	streptomycin 3''-adenylyltransferase activity|ATP:streptomycin 3''-adenylyltransferase activity|AAD (3'')											KEGG_REACTION:R02226|EC:2.7.7.47|RHEA:20245|MetaCyc:STREPTOMYCIN-3-ADENYLYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0034871	biolink:NamedThing	1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity	Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1308		molecular_function											owl:Class	
GO:0097163	biolink:NamedThing	sulfur carrier activity	Covalently binding to sulfur and delivering it to an acceptor molecule.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14455					pr	2011-09-27T10:15:41Z						molecular_function											owl:Class	
GO:0140104	biolink:NamedThing	molecular carrier activity	Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14221|https://github.com/geneontology/go-ontology/issues/20848			Note that a carrier moves with its substrate/cargo, while a transporter does not move with the cargo, but facilitates the change in localization.		pg	2017-09-19T13:10:18Z						molecular_function											owl:Class	
GO:0099592	biolink:NamedThing	endocytosed synaptic vesicle processing via endosome	The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.	got7fsn_ti	synaptic vesicle processing via endosome involved in synaptic vesicle recycling													biological_process											owl:Class	
GO:0043959	biolink:NamedThing	L-erythro-3-methylmalyl-CoA lyase activity	Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA.	got7fsn_ti	HpcH/HpaI aldolase											EC:4.1.3.24		molecular_function											owl:Class	
GO:0010767	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0036461	biolink:NamedThing	BLOC-2 complex binding	Binding to a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.	got7fsn_ti							bf	2014-06-11T09:14:55Z						molecular_function											owl:Class	
GO:0009016	biolink:NamedThing	succinyldiaminopimelate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate.	got7fsn_ti	N-succinyl-L-diaminopimelic glutamic transaminase activity|N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity|succinyldiaminopimelate aminotransferase activity|succinyldiaminopimelate transferase activity											MetaCyc:SUCCINYLDIAMINOPIMTRANS-RXN|RHEA:11960|EC:2.6.1.17|KEGG_REACTION:R04475		molecular_function											owl:Class	
GO:0008486	biolink:NamedThing	diphosphoinositol-polyphosphate diphosphatase activity	Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.	got7fsn_ti	diphosphoinositol-polyphosphate phosphohydrolase activity|DIPP activity|diphosphoinositol polyphosphate phosphohydrolase activity|diphospho-myo-inositol-polyphosphate diphosphohydrolase activity											EC:3.6.1.52|MetaCyc:3.6.1.52-RXN|KEGG_REACTION:R05777		molecular_function											owl:Class	
GO:0033436	biolink:NamedThing	AUG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AUG codon.	got7fsn_ti	ATG codon-amino acid adaptor activity|initiator methionine tRNA|methionine tRNA				Note that in the standard genetic code, ATG codes for methionine, and is the initiator codon.									molecular_function											owl:Class	
GO:0051131	biolink:NamedThing	chaperone-mediated protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.	got7fsn_ti	protein complex assembly, multichaperone pathway|cellular chaperone-mediated protein complex assembly|chaperone activity										GO:0034619			biological_process											owl:Class	
GO:0009361	biolink:NamedThing	succinate-CoA ligase complex (ADP-forming)	A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP.	got7fsn_ti	succinyl-CoA synthetase, ADP-forming													cellular_component											owl:Class	
GO:0106257	biolink:NamedThing	glycerol-3-phosphate dehydrogenase [NADP+] activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP+ = glycerone phosphate + NADH + H+.	got7fsn_ti							hjd	2020-04-03T17:10:44Z				RHEA:11096		molecular_function											owl:Class	
GO:0071984	biolink:NamedThing	maintenance of reproductive diapause	The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	got7fsn_ti							mah	2010-10-21T04:49:28Z						biological_process											owl:Class	
GO:0034877	biolink:NamedThing	isonicotinate dehydrogenase activity	Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor.	got7fsn_ti												UM-BBD_reactionID:r1337		molecular_function											owl:Class	
GO:0039017	biolink:NamedThing	pattern specification involved in pronephros development	Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate.	got7fsn_ti	pattern specification involved in pronephric kidney development						bf	2010-07-02T10:04:39Z						biological_process											owl:Class	
GO:0033956	biolink:NamedThing	beta-apiosyl-beta-glucosidase activity	Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.	got7fsn_ti	isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase activity|isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase activity|7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase activity|furcatin hydrolase activity											MetaCyc:RXN-9156|RHEA:21488|MetaCyc:3.2.1.161-RXN|EC:3.2.1.161		molecular_function											owl:Class	
GO:0044835	biolink:NamedThing	hydrogen generation via nitrogenase	The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria.	got7fsn_ti							jl	2014-02-19T14:59:15Z						biological_process											owl:Class	
GO:0102904	biolink:NamedThing	germacrene C synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = germacrene C + diphosphoric acid.	got7fsn_ti												EC:4.2.3.60|MetaCyc:RXN-8561|RHEA:28302		molecular_function											owl:Class	
GO:0004726	biolink:NamedThing	non-membrane spanning protein tyrosine phosphatase activity	Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.	got7fsn_ti												Reactome:R-HSA-177924|Reactome:R-HSA-177923|Reactome:R-HSA-9635739|Reactome:R-HSA-177935|Reactome:R-HSA-177926		molecular_function											owl:Class	
GO:0102886	biolink:NamedThing	alpha-chamigrene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-chamigrene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8428		molecular_function											owl:Class	
GO:0048843	biolink:NamedThing	negative regulation of axon extension involved in axon guidance	Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.	got7fsn_ti	inhibition of axon extension involved in axon guidance|down-regulation of axon extension involved in axon guidance|down regulation of axon extension involved in axon guidance|downregulation of axon extension involved in axon guidance													biological_process											owl:Class	
GO:0044515	biolink:NamedThing	envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism.	got7fsn_ti							jl	2012-02-26T11:08:08Z						biological_process											owl:Class	
GO:0071761	biolink:NamedThing	IgZ immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish.	got7fsn_ti	IgT immunoglobulin complex|IgT antibody|IgZ antibody				Note that an IgZ immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgZ is found in bony fish, and called IgT in certain species, such as trout.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0033834	biolink:NamedThing	kaempferol 3-O-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.	got7fsn_ti	F3GalTase activity|UDP-galactose:kaempferol 3-O-beta-D-galactosyltransferase activity											MetaCyc:2.4.1.234-RXN|EC:2.4.1.234|RHEA:15709		molecular_function											owl:Class	
GO:0018531	biolink:NamedThing	(S)-6-hydroxynicotine oxidase activity	Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).	got7fsn_ti	(S)-6-hydroxynicotine:oxygen oxidoreductase activity|6-hydroxy-L-nicotine:oxygen oxidoreductase activity|6-hydroxy-L-nicotine oxidase activity|L-6-hydroxynicotine oxidase activity											UM-BBD_reactionID:r0478|RHEA:11880|EC:1.5.3.5|KEGG_REACTION:R03202|MetaCyc:S-6-HYDROXYNICOTINE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0072582	biolink:NamedThing	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.	got7fsn_ti							mah	2011-02-07T01:54:21Z				RHEA:24616		molecular_function											owl:Class	
GO:0075053	biolink:NamedThing	penetration peg formation	The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	symbiont penetration peg initiation|initiation of symbiont penetration peg|symbiont penetration peg formation for entry into host|formation of symbiont penetration peg for entry into host	https://github.com/geneontology/go-ontology/issues/18557			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.						GO:0075057			biological_process											owl:Class	
GO:0102190	biolink:NamedThing	4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) <=> 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O.	got7fsn_ti												MetaCyc:RXN-11958		molecular_function											owl:Class	
GO:0035544	biolink:NamedThing	negative regulation of SNARE complex assembly	Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	got7fsn_ti							bf	2010-05-10T01:51:10Z						biological_process											owl:Class	
GO:0034586	biolink:NamedThing	21U-RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.	got7fsn_ti	21U-RNA catabolism|21U-RNA breakdown|21U-RNA degradation													biological_process											owl:Class	
GO:0016205	biolink:NamedThing	selenocysteine methyltransferase activity	Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.	got7fsn_ti												RHEA:26341|MetaCyc:RXN-11061|EC:2.1.1.280		molecular_function											owl:Class	
GO:0033828	biolink:NamedThing	glucosylglycerol-phosphate synthase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+).	got7fsn_ti	ADP-glucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity|ADPglucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity|GG-phosphate synthase activity|glucosyl-glycerol-phosphate synthase activity|GGPS											RHEA:12881|KEGG_REACTION:R05328|MetaCyc:2.4.1.213-RXN|EC:2.4.1.213		molecular_function											owl:Class	
GO:0010190	biolink:NamedThing	cytochrome b6f complex assembly	Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents.	got7fsn_ti	cytochrome b6f complex biogenesis													biological_process											owl:Class	
GO:0006597	biolink:NamedThing	spermine biosynthetic process	The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.	got7fsn_ti	spermine formation|spermine biosynthesis|spermine synthesis|spermine anabolism													biological_process											owl:Class	
GO:0048312	biolink:NamedThing	intracellular distribution of mitochondria	Any process that establishes the spatial arrangement of mitochondria within the cell.	got7fsn_ti	mitochondria positioning within cell|mitochondrion positioning within cell													biological_process											owl:Class	
GO:0031055	biolink:NamedThing	chromatin remodeling at centromere	Dynamic structural changes in centromeric DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0052693	biolink:NamedThing	epoxyqueuosine reductase activity	Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant.	got7fsn_ti												RHEA:32159|EC:1.17.99.6		molecular_function											owl:Class	
GO:0062184	biolink:NamedThing	testosterone 16-beta-hydroxylase activity	Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							dph	2019-11-26T18:43:43Z				RHEA:46304		molecular_function											owl:Class	
GO:1990489	biolink:NamedThing	anaerobic pectin catabolic process	The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen.	got7fsn_ti	anaerobic pectin degradation						tt	2014-09-20T18:09:53Z						biological_process											owl:Class	
GO:0045490	biolink:NamedThing	pectin catabolic process	The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.	got7fsn_ti	pectin degradation|pectin catabolism|pectin breakdown													biological_process											owl:Class	
GO:0010378	biolink:NamedThing	temperature compensation of the circadian clock	The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.	got7fsn_ti	regulation of the circadian clock by temperature													biological_process											owl:Class	
GO:0010356	biolink:NamedThing	homogentisate geranylgeranyltransferase activity	Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol.	got7fsn_ti														molecular_function											owl:Class	
GO:0060038	biolink:NamedThing	cardiac muscle cell proliferation	The expansion of a cardiac muscle cell population by cell division.	got7fsn_ti	heart muscle cell proliferation|cardiomyocyte proliferation|cardiac myocyte proliferation													biological_process											owl:Class	
GO:0052595	biolink:NamedThing	aliphatic-amine oxidase activity	Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+.	got7fsn_ti	aliphatic-amine:oxygen oxidoreductase(deaminating) activity											EC:1.4.3.21|MetaCyc:AMINEOXID-RXN|RHEA:16153		molecular_function											owl:Class	
GO:2000750	biolink:NamedThing	negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.	got7fsn_ti							mah	2011-06-16T11:51:49Z						biological_process											owl:Class	
GO:0005372	biolink:NamedThing	water transmembrane transporter activity	Enables the transfer of water (H2O) from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0044547	biolink:NamedThing	DNA topoisomerase binding	Binding to a DNA topoisomerase.	got7fsn_ti	DNA topoisomerase I binding						jl	2012-03-22T02:30:37Z			GO:0017033			molecular_function											owl:Class	
GO:0061828	biolink:NamedThing	apical tubulobulbar complex	Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.	got7fsn_ti	apical TBC						dph	2017-01-15T10:41:00Z						cellular_component											owl:Class	
GO:0047808	biolink:NamedThing	D(-)-tartrate dehydratase activity	Catalysis of the reaction: D-tartrate = H(2)O + oxaloacetate.	got7fsn_ti	D-tartrate dehydratase activity|(S,S)-tartrate hydro-lyase activity|(S,S)-tartrate hydro-lyase (oxaloacetate-forming)											MetaCyc:D--TARTRATE-DEHYDRATASE-RXN|RHEA:18289|KEGG_REACTION:R00340|EC:4.2.1.81		molecular_function											owl:Class	
GO:0102143	biolink:NamedThing	carboxynorspermidine dehydrogenase I activity	Catalysis of the reaction: carboxynorspermidine + NADP + H2O <=> L-aspartic acid 4-semialdehyde betaine + trimethylenediaminium + NADPH + H+.	got7fsn_ti												RHEA:34115|MetaCyc:RXN-11565		molecular_function											owl:Class	
GO:1990491	biolink:NamedThing	methane biosynthetic process from methanol and hydrogen	The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen.	got7fsn_ti	methanogenesis from methanol and hydrogen|methane biosynthesis from methanol and hydrogen						tt	2014-09-21T01:08:40Z						biological_process											owl:Class	
GO:0018851	biolink:NamedThing	alpha-pinene-oxide decyclase activity	Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal.	got7fsn_ti	alpha-pinene-oxide lyase (decyclizing)|alpha-pinene oxide lyase activity											UM-BBD_reactionID:r0743|MetaCyc:ALPHA-PINENE-OXIDE-DECYCLASE-RXN|RHEA:16693|KEGG_REACTION:R04040|EC:5.5.1.10		molecular_function											owl:Class	
GO:0050682	biolink:NamedThing	AF-2 domain binding	Binding to an AF-2 protein domain, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.	got7fsn_ti														molecular_function											owl:Class	
GO:0051587	biolink:NamedThing	inhibition of dopamine uptake involved in synaptic transmission	Any process that prevents the activation of the directed movement of dopamine into a cell.	got7fsn_ti	inhibition of dopamine import involved in synaptic transmission													biological_process											owl:Class	
GO:0051585	biolink:NamedThing	negative regulation of dopamine uptake involved in synaptic transmission	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell.	got7fsn_ti	down regulation of dopamine uptake involved in synaptic transmission|negative regulation of dopamine import involved in synaptic transmission|down-regulation of dopamine uptake involved in synaptic transmission|downregulation of dopamine uptake involved in synaptic transmission													biological_process											owl:Class	
GO:0086008	biolink:NamedThing	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti							tb	2011-11-10T08:38:09Z						molecular_function											owl:Class	
GO:0018267	biolink:NamedThing	GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GPI anchor synthesis via N-cysteinyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-cysteinyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-cysteinyl-glycosylphosphatidylinositolethanolamine											RESID:AA0160		biological_process											owl:Class	
GO:0042250	biolink:NamedThing	maintenance of polarity of embryonic epithelium	The maintenance of an established polarized embryonic epithelial sheet.	got7fsn_ti														biological_process											owl:Class	
GO:0039686	biolink:NamedThing	bidirectional double-stranded viral DNA replication	A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.	got7fsn_ti	viral bidirectional dsDNA replication						bf	2013-10-17T14:42:09Z				VZ:1939		biological_process											owl:Class	
GO:0099016	biolink:NamedThing	DNA end degradation evasion by virus	Any process, either active or passive, by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle.  For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases.	got7fsn_ti												VZ:3963		biological_process											owl:Class	
GO:0008761	biolink:NamedThing	UDP-N-acetylglucosamine 2-epimerase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.	got7fsn_ti	UDP-N-acetyl-D-glucosamine 2-epimerase activity|UDP-N-acetylglucosamine 2'-epimerase activity|uridine diphosphoacetylglucosamine 2'-epimerase activity|uridine diphospho-N-acetylglucosamine 2'-epimerase activity|UDP-GlcNAc-2-epimerase activity|uridine diphosphate-N-acetylglucosamine-2'-epimerase activity											MetaCyc:UDPGLCNACEPIM-RXN|EC:5.1.3.14|RHEA:17213|Reactome:R-HSA-4085021|Reactome:R-HSA-4088338		molecular_function											owl:Class	
GO:1990194	biolink:NamedThing	cytoplasmic U snRNP body assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body.	got7fsn_ti	U body assembly						tb	2013-09-12T21:54:20Z						biological_process											owl:Class	
GO:0102205	biolink:NamedThing	cholesterol alpha-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cholesterol = UDP + cholesteryl beta-D-glucoside + H+.	got7fsn_ti	cholesterol UDP-glucosyltransferase activity|cholesterol allpha-glucosyltransferase activity										GO:0051505	MetaCyc:RXN-12127|EC:2.4.1.173|RHEA:61848		molecular_function											owl:Class	
GO:0101014	biolink:NamedThing	[isocitrate dehydrogenase (NADP+)] phosphatase activity	Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate.	got7fsn_ti	isocitrate dehydrogenase kinase/phosphatase activity											MetaCyc:ICITDEHASE-KIN-PHOSPHA		molecular_function											owl:Class	
GO:0031425	biolink:NamedThing	chloroplast RNA processing	The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0071831	biolink:NamedThing	intermediate-density lipoprotein particle clearance	The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti	IDL clearance						mah	2010-09-08T11:26:12Z						biological_process											owl:Class	
GO:0043474	biolink:NamedThing	pigment metabolic process involved in pigmentation	The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.	got7fsn_ti	pigment metabolism during pigmentation|pigment metabolic process during pigmentation													biological_process											owl:Class	
GO:0051583	biolink:NamedThing	dopamine uptake involved in synaptic transmission	The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	got7fsn_ti	dopamine reuptake involved in synaptic transmission|dopamine import involved in synaptic transmission													biological_process											owl:Class	
GO:0047126	biolink:NamedThing	N5-(carboxyethyl)ornithine synthase activity	Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H(2)O + NADP(+) = L-ornithine + H(+) + NADPH + pyruvate.	got7fsn_ti	N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)|5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)											KEGG_REACTION:R00666|EC:1.5.1.24|MetaCyc:1.5.1.24-RXN|RHEA:18661		molecular_function											owl:Class	
GO:0033368	biolink:NamedThing	protease localization to mast cell secretory granule	Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.	got7fsn_ti	protease localization in mast cell secretory granule|protease localisation in mast cell secretory granule													biological_process											owl:Class	
GO:0042796	biolink:NamedThing	snRNA transcription by RNA polymerase III	The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.	got7fsn_ti	snRNA transcription from Pol III promoter|snRNA transcription from RNA polymerase III promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0097150	biolink:NamedThing	neuronal stem cell population maintenance	Any process in by an organism or tissue maintains a population of neuronal stem cells.	got7fsn_ti							pr	2011-08-04T11:18:28Z						biological_process											owl:Class	
GO:0036174	biolink:NamedThing	butane monooxygenase activity	Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O.	got7fsn_ti	sBMO|soluble butane monooxygenase						bf	2012-03-29T10:42:07Z						molecular_function											owl:Class	
GO:0097138	biolink:NamedThing	BAD-BCL-2 complex	A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:37:50Z						cellular_component											owl:Class	
GO:2000213	biolink:NamedThing	positive regulation of glutamate metabolic process	Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.	got7fsn_ti	positive regulation of glutamic acid metabolic process|positive regulation of glutamate metabolism|positive regulation of glutamic acid metabolism						mah	2010-11-03T02:43:59Z						biological_process											owl:Class	
GO:0102874	biolink:NamedThing	1-16:0-2-18:2-digalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-16:0-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.35|MetaCyc:RXN-8365		molecular_function											owl:Class	
GO:0050191	biolink:NamedThing	phosphoglycerate kinase (GTP) activity	Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+).	got7fsn_ti	GTP:3-phospho-D-glycerate 1-phosphotransferase activity											MetaCyc:PHOSPHOGLYCERATE-KINASE-GTP-RXN|RHEA:23332|EC:2.7.2.10|KEGG_REACTION:R01517		molecular_function											owl:Class	
GO:0106381	biolink:NamedThing	purine deoxyribonucleotide salvage	Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis.	got7fsn_ti							hjd	2021-06-11T14:55:33Z						biological_process											owl:Class	
GO:0036337	biolink:NamedThing	Fas signaling pathway	A series of molecular signals initiated by the binding of a ligand to the receptor Fas on the surface of the cell, and ending with regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.	got7fsn_ti	Apo-1 signaling pathway|Fas receptor signaling pathway|CD95 signaling pathway|FAS ligand-Fas signaling pathway|Fas-FasL signaling pathway|FasR signaling pathway|FasL signaling pathway						bf	2012-09-05T10:28:11Z						biological_process											owl:Class	
GO:0060791	biolink:NamedThing	sebaceous gland placode formation	The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.	got7fsn_ti							dph	2009-08-04T12:23:09Z						biological_process											owl:Class	
GO:0061610	biolink:NamedThing	glycerol to glycerone phosphate metabolic process	The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.	got7fsn_ti	glycerol metabolism to DHAP|glycerol to dihydroxyacetone phosphate metabolic process|glycerol metabolism to glycerone phosphate|glycerol metabolism to dihydroxyacetone phosphate|glycerol to DHAP metabolic process						dph	2014-04-03T13:26:21Z						biological_process											owl:Class	
GO:0006071	biolink:NamedThing	glycerol metabolic process	The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	got7fsn_ti	glycerol metabolism											MetaCyc:GLYCEROLMETAB-PWY		biological_process											owl:Class	
GO:0052422	biolink:NamedThing	modulation by host of symbiont catalytic activity	The process in which a host organism effects a change in the enzyme activity of its symbiont organism.	got7fsn_ti	modulation by host of symbiont enzyme activity|modulation by host of symbiont molecular function										GO:0052428			biological_process											owl:Class	
GO:0003986	biolink:NamedThing	acetyl-CoA hydrolase activity	Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+).	got7fsn_ti	acetyl-CoA acylase activity|acetyl coenzyme A acylase activity|acetyl-CoA deacylase activity|acetyl coenzyme A hydrolase activity|acetyl coenzyme A deacylase activity|acetyl-CoA thiol esterase activity											RHEA:20289|Reactome:R-HSA-390304|KEGG_REACTION:R00227|Reactome:R-HSA-2066779|MetaCyc:ACETYL-COA-HYDROLASE-RXN|EC:3.1.2.1		molecular_function											owl:Class	
GO:0110147	biolink:NamedThing	protein maturation by nickel ion transfer	A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation.	got7fsn_ti							kmv	2019-05-31T14:41:20Z						biological_process											owl:Class	
GO:0047234	biolink:NamedThing	raffinose-raffinose alpha-galactotransferase activity	Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose.	got7fsn_ti	raffinose-raffinose a-galactosyltransferase activity|raffinose-raffinose alpha-galactosyltransferase activity|raffinose:raffinose alpha-D-galactosyltransferase activity|raffinose (raffinose donor) galactosyltransferase activity|raffinose:raffinose alpha-galactosyltransferase activity											MetaCyc:2.4.1.166-RXN|RHEA:14125|EC:2.4.1.166		molecular_function											owl:Class	
GO:0031861	biolink:NamedThing	prolactin-releasing peptide receptor binding	Binding to a prolactin-releasing peptide receptor.	got7fsn_ti	prolactin-releasing peptide receptor ligand													molecular_function											owl:Class	
GO:0032198	biolink:NamedThing	MITE transposition	Any process involved in the transposition of miniature inverted-repeat transposable elements (MITEs).	got7fsn_ti	Class III transposition													biological_process											owl:Class	
GO:0051190	biolink:NamedThing	prosthetic group catabolic process	The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.	got7fsn_ti	prosthetic group catabolism|prosthetic group degradation|coenzyme and prosthetic group catabolic process|coenzyme and prosthetic group catabolism|prosthetic group breakdown													biological_process											owl:Class	
GO:0007223	biolink:NamedThing	Wnt signaling pathway, calcium modulating pathway	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).	got7fsn_ti	non-canonical Wnt signaling pathway|Wnt-activated signaling pathway, calcium modulating pathway|frizzled-2 signalling pathway|frizzled-2 signaling pathway|Wnt receptor signaling pathway, calcium modulating pathway													biological_process											owl:Class	
GO:0042988	biolink:NamedThing	X11-like protein binding	Binding to X11-like protein, a neuron-specific adaptor protein.	got7fsn_ti	X11L binding													molecular_function											owl:Class	
GO:0102336	biolink:NamedThing	3-oxo-arachidoyl-CoA synthase activity	Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon dioxide + coenzyme A.	got7fsn_ti												MetaCyc:RXN-13294|RHEA:35319		molecular_function											owl:Class	
GO:0010032	biolink:NamedThing	meiotic chromosome condensation	Compaction of chromatin structure prior to meiosis in eukaryotic cells.	got7fsn_ti	chromosome condensation involved in meiotic cell cycle													biological_process											owl:Class	
GO:0060649	biolink:NamedThing	mammary gland bud elongation	The process in which the mammary gland bud grows along its axis.	got7fsn_ti							dph	2009-05-29T08:50:39Z						biological_process											owl:Class	
GO:0019363	biolink:NamedThing	pyridine nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.	got7fsn_ti	pyridine nucleotide formation|pyridine nucleotide biosynthesis|pyridine nucleotide synthesis|pyridine nucleotide anabolism											MetaCyc:PYRIDNUCSYN-PWY		biological_process											owl:Class	
GO:0035824	biolink:NamedThing	long tract gene conversion	A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor.	got7fsn_ti							bf	2011-05-04T01:06:18Z						biological_process											owl:Class	
GO:0061468	biolink:NamedThing	karyomere	A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division.	got7fsn_ti							dph	2012-10-22T14:19:29Z						cellular_component											owl:Class	
GO:0061611	biolink:NamedThing	mannose to fructose-6-phosphate metabolic process	The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.	got7fsn_ti	mannose metabolism to fructose-6-phosphate						dph	2014-04-03T13:38:50Z						biological_process											owl:Class	
GO:0006013	biolink:NamedThing	mannose metabolic process	The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.	got7fsn_ti	mannose metabolism													biological_process											owl:Class	
GO:0140020	biolink:NamedThing	DNA methyltransferase complex	A protein complex that possesses DNA methyltransferase activity.	got7fsn_ti							pg	2017-04-06T19:12:09Z						cellular_component											owl:Class	
GO:0031881	biolink:NamedThing	type 4 somatostatin receptor binding	Binding to a type 4 somatostatin receptor.	got7fsn_ti	type 4 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0005427	biolink:NamedThing	proton-dependent oligopeptide secondary active transmembrane transporter activity	Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.	got7fsn_ti	hydrogen/oligopeptide symporter|proton-dependent oligopeptide transporter activity													molecular_function											owl:Class	
GO:0018723	biolink:NamedThing	3-phenanthrol sulfotransferase activity	Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate.	got7fsn_ti	3-phenanthrol sulphotransferase activity											UM-BBD_reactionID:r0561		molecular_function											owl:Class	
GO:0140533	biolink:NamedThing	suppression of host RNAi-mediated antiviral immune response	Any process in which a symbiont stops, prevents, or reduces the rate or extent of the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	suppression of host RNAi-mediated gene silencing|suppression of host RNAi-mediated antiviral immunity	https://github.com/geneontology/go-ontology/issues/19958					pg	2020-10-28T07:55:27Z						biological_process											owl:Class	
GO:0001502	biolink:NamedThing	cartilage condensation	The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.	got7fsn_ti														biological_process											owl:Class	
GO:0034555	biolink:NamedThing	3,3'-dibromobisphenol A reductive dehalogenase activity	Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr.	got7fsn_ti												UM-BBD_reactionID:r0844|EC:1.97.1.-		molecular_function											owl:Class	
GO:0047223	biolink:NamedThing	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP.	got7fsn_ti	elongation 3-beta-GalNAc-transferase activity|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to -D-galactose of beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase (elongating)|elongation 3beta-GalNAc-transferase activity											MetaCyc:2.4.1.146-RXN|Reactome:R-HSA-5617096|Reactome:R-HSA-5617037|EC:2.4.1.146		molecular_function											owl:Class	
GO:0042744	biolink:NamedThing	hydrogen peroxide catabolic process	The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).	got7fsn_ti	hydrogen peroxide scavenging|detoxification of H2O2|hydrogen peroxide catabolism|hydrogen peroxide removal|hydrogen peroxide degradation|H2O2 catabolic process|detoxification of hydrogen peroxide|hydrogen peroxide breakdown|H2O2 scavenging													biological_process											owl:Class	
GO:0018831	biolink:NamedThing	5-chloro-1,2,4-trihydroxybenzene dechlorinase activity	Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone.	got7fsn_ti												EC:4.5.1.-|UM-BBD_reactionID:r0666		molecular_function											owl:Class	
GO:0051116	biolink:NamedThing	cobaltochelatase activity	Catalysis of the reaction: ATP + Co(2+) + H(2)O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H(+) + phosphate.	got7fsn_ti	CobNST|hydrogenobyrinic acid a,c-diamide cobaltochelatase activity|hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming)|CobN-CobST											EC:6.6.1.2|KEGG_REACTION:R05227|MetaCyc:R342-RXN|RHEA:15341		molecular_function											owl:Class	
GO:0048921	biolink:NamedThing	posterior lateral line neuromast cupula development	The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.	got7fsn_ti														biological_process											owl:Class	
GO:0098613	biolink:NamedThing	methaneselenol methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol => S-adenosyl-L-homocysteine + dimethyl selenide.	got7fsn_ti												Reactome:R-HSA-2408541		molecular_function											owl:Class	
GO:0006690	biolink:NamedThing	icosanoid metabolic process	The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.	got7fsn_ti	icosanoid metabolism|eicosanoid metabolism|eicosanoid metabolic process													biological_process											owl:Class	
GO:0043757	biolink:NamedThing	adenosylcobinamide-phosphate synthase activity	Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide.	got7fsn_ti	CbiB|adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming)|AdoCbi-P synthase activity											EC:6.3.1.10|MetaCyc:RXN-6261|RHEA:21896		molecular_function											owl:Class	
GO:0034977	biolink:NamedThing	ABIN2-NFKB1-MAP3K8 complex	A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages.	got7fsn_ti	ABIN2-NFKB1-TPL-1 complex													cellular_component											owl:Class	
GO:0072699	biolink:NamedThing	protein localization to cortical microtubule cytoskeleton	A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton.	got7fsn_ti	protein localisation to cortical microtubule cytoskeleton						mah	2012-04-11T01:23:36Z						biological_process											owl:Class	
GO:0034860	biolink:NamedThing	2-mercaptobenzothiazole desulfurase activity	Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor.	got7fsn_ti												UM-BBD_reactionID:r1288|EC:4.4.1.-		molecular_function											owl:Class	
GO:0043423	biolink:NamedThing	3-phosphoinositide-dependent protein kinase binding	Binding to a 3-phosphoinositide-dependent protein kinase.	got7fsn_ti	phosphatidylinositol-3-phosphate-dependent protein kinase binding													molecular_function											owl:Class	
GO:0043057	biolink:NamedThing	backward locomotion	Posterior movement of an organism, e.g. following the direction of the tail of an animal.	got7fsn_ti														biological_process											owl:Class	
GO:0031734	biolink:NamedThing	CCR9 chemokine receptor binding	Binding to a CCR9 chemokine receptor.	got7fsn_ti	CCR9 chemokine receptor ligand													molecular_function											owl:Class	
GO:0032619	biolink:NamedThing	interleukin-16 production	The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-16 production|pro-interleukin-16 production|interleukin-16 biosynthetic process|LCF production|interleukin-16 secretion										GO:0042234|GO:0072614			biological_process											owl:Class	
GO:0045793	biolink:NamedThing	positive regulation of cell size	Any process that increases cell size.	got7fsn_ti	upregulation of cell size|up regulation of cell size|activation of cell size|stimulation of cell size|up-regulation of cell size													biological_process											owl:Class	
GO:0022877	biolink:NamedThing	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti	fructose PTS transporter activity													molecular_function											owl:Class	
GO:0004552	biolink:NamedThing	octanol dehydrogenase activity	Catalysis of the reaction: 1-octanol + NAD(+) = 1-octanal + H(+) + NADH.	got7fsn_ti	1-octanol dehydrogenase activity|octanol:NAD+ oxidoreductase activity											MetaCyc:OCTANOL-DEHYDROGENASE-RXN|KEGG_REACTION:R02878|EC:1.1.1.73|RHEA:24620		molecular_function											owl:Class	
GO:0008747	biolink:NamedThing	N-acetylneuraminate lyase activity	Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.	got7fsn_ti	N-acetylneuraminate pyruvate-lyase activity|NPL|N-acetylneuraminic aldolase activity|N-acetylneuraminic acid lyase activity|N-acetylneuraminic lyase activity|sialic acid aldolase activity|sialic aldolase activity|N-acetylneuraminate aldolase activity|neuraminic aldolase activity|sialate lyase activity|NANA lyase activity|NALase activity|acetylneuraminate pyruvate-lyase activity|neuraminate aldolase activity|neuraminic acid aldolase activity|acetylneuraminate lyase activity|N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)|N-acetylneuraminic acid aldolase activity											MetaCyc:ACNEULY-RXN|Reactome:R-HSA-4085217|KEGG_REACTION:R01811|EC:4.1.3.3|RHEA:23296		molecular_function											owl:Class	
GO:0035543	biolink:NamedThing	positive regulation of SNARE complex assembly	Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	got7fsn_ti							bf	2010-05-10T01:50:02Z						biological_process											owl:Class	
GO:0046196	biolink:NamedThing	4-nitrophenol catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.	got7fsn_ti	4-nitrophenol degradation|4-nitrophenol catabolism|4-nitrophenol breakdown													biological_process											owl:Class	
GO:0016492	biolink:NamedThing	G protein-coupled neurotensin receptor activity	Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.	got7fsn_ti	G-protein coupled neurotensin receptor activity|G protein coupled neurotensin receptor activity|neurotensin receptor activity, G protein coupled|neurotensin receptor activity, G-protein coupled													molecular_function											owl:Class	
GO:0047445	biolink:NamedThing	3-hydroxy-3-isohexenylglutaryl-CoA lyase activity	Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H(+) = 7-methyl-3-oxooct-6-enoyl-CoA + acetate.	got7fsn_ti	beta-hydroxy-beta-isohexenylglutaryl CoA-lyase activity|3-hydroxy-3-isohexenylglutaryl coenzyme A lyase activity|hydroxyisohexenylglutaryl-CoA:acetatelyase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)|3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase activity											UM-BBD_reactionID:r1168|RHEA:23084|MetaCyc:4.1.3.26-RXN|KEGG_REACTION:R08090|EC:4.1.3.26		molecular_function											owl:Class	
GO:0004941	biolink:NamedThing	beta2-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors.	got7fsn_ti	beta2 adrenoceptor													molecular_function											owl:Class	
GO:0050090	biolink:NamedThing	mannuronate reductase activity	Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+.	got7fsn_ti	D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming))|D-mannonate:NAD(P)+ 6-oxidoreductase activity|mannonate dehydrogenase (NAD(P)+)|mannonate dehydrogenase activity|mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase activity											EC:1.1.1.131|MetaCyc:MANNURONATE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0102747	biolink:NamedThing	chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity	Catalysis of the reaction: H+ + chlorophyllide a(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) <=> geranylgeranyl-chlorophyll a + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-7663		molecular_function											owl:Class	
GO:0008840	biolink:NamedThing	4-hydroxy-tetrahydrodipicolinate synthase activity	Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O.	got7fsn_ti	DHDPS activity|dihydropicolinate synthetase activity|L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]|dihydrodipicolinate synthetase activity|dihydrodipicolinic acid synthase activity|dihydrodipicolinate synthase activity|L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing)											KEGG_REACTION:R02292|MetaCyc:DIHYDRODIPICSYN-RXN|EC:4.3.3.7|RHEA:14845		molecular_function											owl:Class	
GO:0002083	biolink:NamedThing	4-hydroxybenzoate decaprenyltransferase activity	Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.	got7fsn_ti												RHEA:44564|Reactome:R-HSA-2162192|EC:2.5.1.39|MetaCyc:RXN-9230		molecular_function											owl:Class	
GO:0031781	biolink:NamedThing	type 3 melanocortin receptor binding	Binding to a type 3 melanocortin receptor.	got7fsn_ti	type 3 melanocortin receptor ligand													molecular_function											owl:Class	
GO:0000111	biolink:NamedThing	nucleotide-excision repair factor 2 complex	One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p.	got7fsn_ti	NEF2 complex				Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.									cellular_component											owl:Class	
GO:0031828	biolink:NamedThing	type 2C serotonin receptor binding	Binding to a type 2C serotonin receptor.	got7fsn_ti	type 2C serotonin receptor ligand|5-hydroxytryptamine 2C receptor binding													molecular_function											owl:Class	
GO:0072019	biolink:NamedThing	proximal convoluted tubule development	The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.	got7fsn_ti							mah	2010-01-25T02:35:35Z						biological_process											owl:Class	
GO:0099580	biolink:NamedThing	ion antiporter activity involved in regulation of postsynaptic membrane potential	Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.	got7fsn_ti	ion antiporter activity involved in regulation of post-synaptic membrane potential													molecular_function											owl:Class	
GO:0004745	biolink:NamedThing	NAD-retinol dehydrogenase activity	Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.	got7fsn_ti	retinol dehydrogenase activity|retinol (vitamin A1) dehydrogenase activity|retinene reductase activity|retinal reductase activity|all-trans retinol dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/20980										Reactome:R-HSA-2454081|Reactome:R-HSA-2466832|EC:1.1.1.105|MetaCyc:RETINOL-DEHYDROGENASE-RXN|Reactome:R-HSA-5362518|Reactome:R-HSA-5362564|RHEA:21284|Reactome:R-HSA-5362721		molecular_function											owl:Class	
GO:0008662	biolink:NamedThing	1-phosphofructokinase activity	Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate.	got7fsn_ti	fructose-1-phosphate kinase activity|phosphofructokinase 1|fructose 1-phosphate kinase activity|ATP:D-fructose-phosphate 6-phosphotransferase activity|D-fructose-1-phosphate kinase activity|1-phosphofructokinase (phosphorylating)											MetaCyc:1PFRUCTPHOSN-RXN|EC:2.7.1.56|RHEA:14213		molecular_function											owl:Class	
GO:0102254	biolink:NamedThing	neoagarotetraose 1,3-alpha-3,6-anhydro-L-galactosidase activity	Catalysis of the reaction: neoagarotetraose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agarotriose.	got7fsn_ti												EC:3.2.1.159|MetaCyc:RXN-12427		molecular_function											owl:Class	
GO:0008087	biolink:NamedThing	light-activated voltage-gated calcium channel complex	A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus.	got7fsn_ti	light-activated voltage-dependent calcium channel complex|light-activated voltage-sensitive calcium channel complex|light-activated voltage gated calcium channel complex													cellular_component											owl:Class	
GO:0036004	biolink:NamedThing	GAF domain binding	Binding to a GAF protein domain.	got7fsn_ti							bf	2011-09-20T04:20:42Z						molecular_function											owl:Class	
GO:0004799	biolink:NamedThing	thymidylate synthase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.	got7fsn_ti	thymidylate synthetase activity|TMP synthetase activity|5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity|dTMP synthase activity|methylenetetrahydrofolate:dUMP C-methyltransferase activity											RHEA:12104|EC:2.1.1.45|KEGG_REACTION:R02101|Reactome:R-HSA-73605|MetaCyc:THYMIDYLATESYN-RXN		molecular_function											owl:Class	
GO:0000247	biolink:NamedThing	C-8 sterol isomerase activity	Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols.	got7fsn_ti	delta-8-delta-7 sterol isomerase activity													molecular_function											owl:Class	
GO:0031711	biolink:NamedThing	bradykinin receptor binding	Binding to a bradykinin receptor.	got7fsn_ti	bradykinin receptor ligand													molecular_function											owl:Class	
GO:0044813	biolink:NamedThing	glycolytic fermentation via PFOR pathway	The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species.	got7fsn_ti							jl	2013-09-18T16:04:00Z						biological_process											owl:Class	
GO:0000939	biolink:NamedThing	inner kinetochore	The region of a kinetochore closest to centromeric DNA; in mammals the CREST antigens (CENP proteins) are found in this layer; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome.	got7fsn_ti	inner kinetochore of condensed nuclear chromosome|inner centromere core complex|inner kinetochore plate|inner kinetochore of condensed chromosome|condensed nuclear chromosome inner kinetochore|condensed chromosome inner kinetochore	https://github.com/geneontology/go-ontology/issues/21126									GO:0000941			cellular_component											owl:Class	
GO:0016914	biolink:NamedThing	follicle-stimulating hormone complex	A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity.	got7fsn_ti	follicle stimulating hormone complex|FSH complex													cellular_component											owl:Class	
GO:1900568	biolink:NamedThing	chanoclavine-I aldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of chanoclavine-I aldehyde.	got7fsn_ti	chanoclavine-I aldehyde breakdown|chanoclavine-I aldehyde catabolism|chanoclavine-I aldehyde degradation						di	2012-05-15T06:31:21Z						biological_process											owl:Class	
GO:0047524	biolink:NamedThing	16-hydroxysteroid epimerase activity	Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.	got7fsn_ti	16-hydroxysteroid 16-epimerase activity											RHEA:15829|MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN|EC:5.1.99.2		molecular_function											owl:Class	
GO:0045160	biolink:NamedThing	myosin I complex	A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement.	got7fsn_ti														cellular_component											owl:Class	
GO:0045145	biolink:NamedThing	single-stranded DNA 5'-3' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule.	got7fsn_ti	single-stranded DNA specific 5'-3' exodeoxyribonuclease activity|ssDNA-specific 5'-3' exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0046861	biolink:NamedThing	glyoxysomal membrane	The lipid bilayer surrounding a glyoxysome.	got7fsn_ti	glyoxysome membrane													cellular_component											owl:Class	
GO:0097620	biolink:NamedThing	(R)-mandelate dehydrogenase activity	Catalysis of the reaction: (R)-2-hydroxy-2-phenylacetate + acceptor = phenylglyoxylate + reduced acceptor.	got7fsn_ti	D-mandelate dehydrogenase activity				In the yeast Rhodotorula graminis, (R)-mandelate dehydrogenase is the first enzyme of the mandelate pathway, and catalyzes the NAD-dependent oxidation of (R)-mandelate to phenylglyoxylate.		pr	2014-07-30T09:53:23Z				RHEA:43112		molecular_function											owl:Class	
GO:0002436	biolink:NamedThing	immune complex clearance by monocytes and macrophages	The process of immune complex clearance by monocytes or macrophages.	got7fsn_ti														biological_process											owl:Class	
GO:1900612	biolink:NamedThing	F-9775B metabolic process	The chemical reactions and pathways involving F-9775B.	got7fsn_ti	F-9775B metabolism						di	2012-05-15T07:03:01Z						biological_process											owl:Class	
GO:0061142	biolink:NamedThing	mesothelial-mesenchymal cell signaling involved in early lung development	Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung.	got7fsn_ti	mesothelial-mesenchymal cell signalling involved in early lung development						dph	2010-05-25T09:35:32Z						biological_process											owl:Class	
GO:0060495	biolink:NamedThing	cell-cell signaling involved in lung development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.	got7fsn_ti	cell-cell signalling involved in lung development													biological_process											owl:Class	
GO:0001720	biolink:NamedThing	conversion of lysyl-tRNA to pyrrolysyl-tRNA	The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).	got7fsn_ti														biological_process											owl:Class	
GO:0016630	biolink:NamedThing	protochlorophyllide reductase activity	Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+.	got7fsn_ti	NADPH2-protochlorophyllide oxidoreductase activity|protochlorophyllide photooxidoreductase activity|NADPH-protochlorophyllide oxidoreductase activity|protochlorophyllide oxidoreductase activity|chlorophyllide-a:NADP+ 7,8-oxidoreductase activity|NADPH-protochlorophyllide reductase activity											MetaCyc:RXN1F-10|EC:1.3.1.33|RHEA:11132		molecular_function											owl:Class	
GO:0018474	biolink:NamedThing	2-carboxybenzaldehyde dehydrogenase activity	Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate.	got7fsn_ti												UM-BBD_reactionID:r0490|EC:1.2.1.-		molecular_function											owl:Class	
GO:0018082	biolink:NamedThing	peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine	The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine.	got7fsn_ti	peptidyl-(Z)-dehydrobutyrine synthesis from peptidyl-threonine|peptidyl-(Z)-dehydrobutyrine anabolism from peptidyl-threonine|peptidyl-(Z)-dehydrobutyrine formation from peptidyl-threonine											RESID:AA0182		biological_process											owl:Class	
GO:0004355	biolink:NamedThing	glutamate synthase (NADPH) activity	Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.	got7fsn_ti	NADPH-glutamate synthase activity|NADPH GOGAT|L-glutamate:NADP+ oxidoreductase (transaminating)|L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity|glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity|L-glutamate synthetase activity|glutamine-ketoglutaric aminotransferase activity|L-glutamate synthase activity|GOGAT activity|NADPH-dependent glutamate synthase activity|glutamate synthetase (NADP) activity|glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity|NADPH-linked glutamate synthase				Note that this term has a MetaCyc pathway reference as the pathway only has a single step.							MetaCyc:GLUTAMATESYN-RXN|EC:1.4.1.13|RHEA:15501|MetaCyc:GLUGLNSYN-PWY|MetaCyc:GLUTSYN-PWY|KEGG_REACTION:R00114		molecular_function											owl:Class	
GO:0014846	biolink:NamedThing	esophagus smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.	got7fsn_ti	oesophagus smooth muscle contraction													biological_process											owl:Class	
GO:0070303	biolink:NamedThing	negative regulation of stress-activated protein kinase signaling cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.	got7fsn_ti	negative regulation of stress-activated protein kinase signalling pathway|negative regulation of stress-activated protein kinase signaling pathway|negative regulation of SAPK signaling pathway|down regulation of stress-activated protein kinase signaling pathway|downregulation of stress-activated protein kinase signaling pathway|down-regulation of stress-activated protein kinase signaling pathway|inhibition of stress-activated protein kinase signaling pathway													biological_process											owl:Class	
GO:0004113	biolink:NamedThing	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity	Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.	got7fsn_ti	CNPase activity|2',3'-cyclic nucleoside monophosphate phosphodiesterase|2':3'-cyclic nucleotide 3'-phosphodiesterase activity|cyclic-CMP phosphodiesterase activity|cyclic 2',3'-nucleotide 3'-phosphodiesterase activity|2':3'-CNMP-3'-ase activity|nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase activity|2',3'-cyclic nucleotide 3'-phosphohydrolase activity|cyclic 2',3'-nucleotide phosphodiesterase|2',3'-cyclic nucleotide 3'-phosphodiesterase activity|2',3'-cyclic AMP phosphodiesterase activity|2',3'-cyclic nucleotide phosphohydrolase											EC:3.1.4.37|RHEA:14489|MetaCyc:3.1.4.37-RXN		molecular_function											owl:Class	
GO:0044785	biolink:NamedThing	metaphase/anaphase transition of meiotic cell cycle	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis.	got7fsn_ti	meiotic metaphase/anaphase transition						jl	2013-05-02T13:11:28Z						biological_process											owl:Class	
GO:0021976	biolink:NamedThing	medulla reticulospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.	got7fsn_ti														biological_process											owl:Class	
GO:0032618	biolink:NamedThing	interleukin-15 production	The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-15 biosynthetic process|interleukin-15 secretion|IL-15 production										GO:0072613|GO:0042233			biological_process											owl:Class	
GO:0043129	biolink:NamedThing	surfactant homeostasis	Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli.	got7fsn_ti														biological_process											owl:Class	
GO:0071324	biolink:NamedThing	cellular response to disaccharide stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.	got7fsn_ti							mah	2009-12-10T05:26:14Z						biological_process											owl:Class	
GO:0044729	biolink:NamedThing	hemi-methylated DNA-binding	Binding to double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.	got7fsn_ti	double-stranded hemi-methylated DNA binding						jl	2012-10-24T14:58:14Z						molecular_function											owl:Class	
GO:0003346	biolink:NamedThing	epicardium-derived cell migration to the myocardium	The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium.	got7fsn_ti							dph	2009-12-01T11:00:42Z						biological_process											owl:Class	
GO:0030730	biolink:NamedThing	sequestering of triglyceride	The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.	got7fsn_ti	storage of triglyceride|retention of triglyceride|triglyceride sequestration|triglyceride retention|sequestration of triglyceride|retention of triacylglycerol|triglyceride sequestering|triacylglycerol storage|triacylglycerol retention|storage of triacylglycerol|triacylglycerol sequestration|triglyceride storage|triacylglycerol sequestering|sequestration of triacylglycerol|sequestering of triacylglycerol													biological_process											owl:Class	
GO:0043846	biolink:NamedThing	DNA polymerase III, clamp loader complex	A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.	got7fsn_ti	DNA polymerase III, DnaX subcomplex|clamp loader complex|DNA polymerase III, DnaX complex													cellular_component											owl:Class	
GO:1990023	biolink:NamedThing	mitotic spindle midzone	The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.	got7fsn_ti							vw	2013-02-05T15:41:48Z						cellular_component											owl:Class	
GO:0018753	biolink:NamedThing	cyanuric acid amidohydrolase activity	Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2.	got7fsn_ti												EC:3.5.2.15|RHEA:14641|MetaCyc:R468-RXN|UM-BBD_reactionID:r0116		molecular_function											owl:Class	
GO:0070979	biolink:NamedThing	protein K11-linked ubiquitination	A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.	got7fsn_ti							mah	2009-10-26T04:50:57Z						biological_process											owl:Class	
GO:0052924	biolink:NamedThing	all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity	Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate.	got7fsn_ti	solanesyl diphosphate synthetase activity|nonaprenyl diphosphate synthase activity|solanesyl diphosphate synthase activity											EC:2.5.1.85|RHEA:27594|MetaCyc:RXN-11486|KEGG_REACTION:R09251		molecular_function											owl:Class	
GO:0070888	biolink:NamedThing	E-box binding	Binding to an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.	got7fsn_ti	E-box promoter binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		mah	2009-08-28T10:37:01Z						molecular_function											owl:Class	
GO:0046684	biolink:NamedThing	response to pyrethroid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.	got7fsn_ti	pyrethroid susceptibility/resistance|pyrethroid resistance													biological_process											owl:Class	
GO:0102347	biolink:NamedThing	trans-arachidon-2-enoyl-CoA reductase activity	Catalysis of the reaction: icosanoyl-CoA(4-) + NADP(3-) <=> trans-2-icosenoyl-CoA(4-) + NADPH(4-) + H+.	got7fsn_ti												MetaCyc:RXN-13306		molecular_function											owl:Class	
GO:0047093	biolink:NamedThing	4-hydroxyquinoline 3-monooxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-4-ol = H(2)O + NAD(+) + quinoline-3,4-diol.	got7fsn_ti	quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating)|1-H-4-oxoquinoline 3-monooxygenase activity|quinolin-4(1H)-one 3-monooxygenase activity											EC:1.14.13.62|RHEA:19325|MetaCyc:1.14.13.62-RXN|KEGG_REACTION:R05154		molecular_function											owl:Class	
GO:0098577	biolink:NamedThing	inactive sex chromosome	A sex chromosome that has been inactivated.	got7fsn_ti	inactivated sex chromosome													cellular_component											owl:Class	
GO:0140547	biolink:NamedThing	acquisition of seed longevity	The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19829					pg	2020-11-11T21:28:55Z						biological_process											owl:Class	
GO:0052910	biolink:NamedThing	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA.	got7fsn_ti	rRNA methyltransferase ermC' activity|ermC 23S rRNA methyltransferase activity|rRNA:m(6)A methyltransferase ermC' activity											EC:2.1.1.184|MetaCyc:RXN-11597|RHEA:42784		molecular_function											owl:Class	
GO:0047492	biolink:NamedThing	xanthan lyase activity	Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain.	got7fsn_ti												EC:4.2.2.12|MetaCyc:4.2.2.12-RXN		molecular_function											owl:Class	
GO:0140499	biolink:NamedThing	negative regulation of mitotic spindle assembly checkpoint signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19818					pg	2020-07-22T15:44:06Z						biological_process											owl:Class	
GO:0002454	biolink:NamedThing	peripheral B cell deletion	The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.	got7fsn_ti	peripheral B lymphocyte deletion|peripheral B-cell deletion|peripheral B-lymphocyte deletion													biological_process											owl:Class	
GO:0090437	biolink:NamedThing	socket cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support.	got7fsn_ti							tb	2012-07-31T17:01:28Z						biological_process											owl:Class	
GO:0050628	biolink:NamedThing	2-oxopropyl-CoM reductase (carboxylating) activity	Catalysis of the reaction: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO(2) + NADPH.	got7fsn_ti	2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating)|2-KPCC activity|NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase activity|NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase activity											KEGG_REACTION:R05713|UM-BBD_reactionID:r0854|RHEA:16977|MetaCyc:1.8.1.5-RXN|EC:1.8.1.5		molecular_function											owl:Class	
GO:0102540	biolink:NamedThing	D-mannose 6-phosphate 1-epimerase activity	Catalysis of the reaction: alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate.	got7fsn_ti												MetaCyc:RXN-14815		molecular_function											owl:Class	
GO:0033893	biolink:NamedThing	ribonuclease IV activity	Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.	got7fsn_ti	endoribonuclease IV activity											EC:3.1.26.6|MetaCyc:3.1.26.6-RXN		molecular_function											owl:Class	
GO:0035255	biolink:NamedThing	ionotropic glutamate receptor binding	Binding to an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels.	got7fsn_ti														molecular_function											owl:Class	
GO:0004089	biolink:NamedThing	carbonate dehydratase activity	Catalysis of the reaction: H2CO3 = CO2 + H2O.	got7fsn_ti	carboxyanhydrase activity|carbonic dehydratase activity|carbonate anhydrase activity|carbonic anhydrase activity|anhydrase activity|carbonate hydro-lyase (carbon-dioxide-forming)|carbonate hydro-lyase activity|carbonic anhydrase A|carbonic acid anhydrase activity											Reactome:R-HSA-1475436|Reactome:R-HSA-1475026|Reactome:R-HSA-1475028|EC:4.2.1.1|Reactome:R-HSA-1475435|Reactome:R-HSA-1475017|RHEA:10748|MetaCyc:CARBODEHYDRAT-RXN|Reactome:R-HSA-1237059|Reactome:R-HSA-1237045|Reactome:R-HSA-1237081|Reactome:R-HSA-1475022|Reactome:R-HSA-1237047|Reactome:R-HSA-1475032|Reactome:R-HSA-1475025		molecular_function											owl:Class	
GO:0007139	biolink:NamedThing	meiotic telophase II	The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0102743	biolink:NamedThing	eriodictyol,NADPH:oxygen oxidoreductase activity	Catalysis of the reaction: H+ + eriodictyol + NADPH + O2 <=> 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) + NADP + 2 H2O.	got7fsn_ti												MetaCyc:RXN-7653		molecular_function											owl:Class	
GO:0005135	biolink:NamedThing	interleukin-3 receptor binding	Binding to an interleukin-3 receptor.	got7fsn_ti	IL-3|interleukin-3 receptor ligand													molecular_function											owl:Class	
GO:0007512	biolink:NamedThing	adult heart development	The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure.	got7fsn_ti	adult cardiac development													biological_process											owl:Class	
GO:0047457	biolink:NamedThing	exo-(1,4)-alpha-D-glucan lyase activity	Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose.	got7fsn_ti	alpha-1,4-glucan lyase activity|alpha-(1->4)-glucan 1,5-anhydro-D-fructose eliminase activity|exo-(1->4)-alpha-D-glucan lyase activity|(1->4)-alpha-D-glucan exo-4-lyase (1,5-anhydro-D-fructose-forming)|alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase activity|exo-alpha-1,4-glucan lyase activity|alpha-1,4-glucan exo-lyase activity											EC:4.2.2.13|MetaCyc:4.2.2.13-RXN		molecular_function											owl:Class	
GO:0102696	biolink:NamedThing	cis-zeatin UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP.	got7fsn_ti												MetaCyc:RXN-4734		molecular_function											owl:Class	
GO:0008973	biolink:NamedThing	phosphopentomutase activity	Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate.	got7fsn_ti	deoxyribose phosphomutase activity|alpha-D-ribose 1,5-phosphomutase activity|phosphodeoxyribomutase activity|alpha-D-glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate phosphotransferase activity|phosphoribomutase activity|deoxyribomutase activity|D-ribose 1,5-phosphomutase activity											Reactome:R-HSA-8982667|Reactome:R-HSA-6787329|RHEA:18793|MetaCyc:PPENTOMUT-RXN|EC:5.4.2.7		molecular_function											owl:Class	
GO:0039616	biolink:NamedThing	T=2 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers.	got7fsn_ti					The T=2 symmetry is an non-official appellation; strictly speaking the capsid has a T=1 symmetry with each unit composed of a homodimer.		bf	2012-07-18T02:01:55Z				VZ:838		cellular_component											owl:Class	
GO:0023031	biolink:NamedThing	MHC class Ib protein binding, via lateral surface	Binding to a major histocompatibility complex class Ib molecules via the lateral surface.	got7fsn_ti								2010-02-16T09:30:50Z						molecular_function											owl:Class	
GO:0008413	biolink:NamedThing	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity	Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) + H2O = 8-oxo-7,8-dihydroguanosine diphosphate (8-oxo-GDP) +  phosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.	got7fsn_ti	8-oxo-7,8-dihydroguanosine triphosphatase activity|7,8-dihydro-8-oxoguanine-triphosphatase activity|8-oxo-7,8-dihydroguanine triphosphatase activity|8-oxo-GTPase activity											RHEA:60032|EC:3.6.1.69		molecular_function											owl:Class	
GO:0071124	biolink:NamedThing	alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex	A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2.	got7fsn_ti	ITGA1-ITGB1-PTPN2 complex						mah	2009-11-13T02:22:51Z						cellular_component											owl:Class	
GO:0000969	biolink:NamedThing	tRNA exon ligation utilizing ATP as source of linkage phosphate	A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species.	got7fsn_ti							krc	2009-04-28T10:29:37Z						biological_process											owl:Class	
GO:0097108	biolink:NamedThing	hedgehog family protein binding	Binding to a member of the hedgehog protein family, signaling proteins involved in development.	got7fsn_ti							pr	2011-07-28T10:06:45Z						molecular_function											owl:Class	
GO:0030380	biolink:NamedThing	interleukin-17E receptor binding	Binding to an interleukin-17E receptor.	got7fsn_ti	interleukin-17E receptor ligand|IL-17E													molecular_function											owl:Class	
GO:0031908	biolink:NamedThing	glyoxysomal lumen	The volume enclosed by the membranes of a glyoxysome.	got7fsn_ti														cellular_component											owl:Class	
GO:0047674	biolink:NamedThing	apiose 1-reductase activity	Catalysis of the reaction: D-apiitol + NAD(+) = D-apiose + H(+) + NADH.	got7fsn_ti	D-apiose reductase activity|D-apiitol:NAD+ 1-oxidoreductase activity|D-apiitol reductase activity											EC:1.1.1.114|KEGG_REACTION:R03577|MetaCyc:APIOSE-1-REDUCTASE-RXN|RHEA:15301		molecular_function											owl:Class	
GO:0033638	biolink:NamedThing	modulation by symbiont of host response to heat	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response to heat shock													biological_process											owl:Class	
GO:0018633	biolink:NamedThing	dimethyl sulfide monooxygenase activity	Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde.	got7fsn_ti	dimethyl sulphide monooxygenase activity											UM-BBD_reactionID:r0208|EC:1.14.13.-		molecular_function											owl:Class	
GO:0102557	biolink:NamedThing	protopanaxadiol 6-hydroxylase activity	Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ <=> protopanaxatriol + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-14978|EC:1.14.14.121|RHEA:22272		molecular_function											owl:Class	
GO:0036048	biolink:NamedThing	protein desuccinylation	The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein.	got7fsn_ti							bf	2011-12-12T09:42:35Z						biological_process											owl:Class	
GO:0106225	biolink:NamedThing	peptidyl-lysine 2-hydroxyisobutyrylation	The 2-hydroxyisobutyrylation of a lysine residue in a protein.	got7fsn_ti							hjd	2019-10-17T18:51:15Z						biological_process											owl:Class	
GO:0002321	biolink:NamedThing	natural killer cell progenitor differentiation	The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor.	got7fsn_ti														biological_process											owl:Class	
GO:0036403	biolink:NamedThing	arachidonate 8(S)-lipoxygenase activity	Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.	got7fsn_ti	8(S)-lipoxygenase activity|8-lipoxygenase (S-type)				This activity produces the S-enantiomer of HPETE, 8(S)-HPETE. For the reaction producing the S-enantiomer, see GO:0047677.		bf	2013-08-14T11:48:46Z				RHEA:38675|KEGG_REACTION:R07053		molecular_function											owl:Class	
GO:0060062	biolink:NamedThing	Spemann organizer formation at the dorsal lip of the blastopore	Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.	got7fsn_ti	Spemann's organizer formation at the dorsal lip of the blastopore|Spemann-Mangold organizer formation at the dorsal lip of the blastopore				Occurs in amphibia, cephalochordates, cyclostomes and cartilaginous fish.									biological_process											owl:Class	
GO:0047061	biolink:NamedThing	glucose-fructose oxidoreductase activity	Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone.	got7fsn_ti	D-glucose:D-fructose oxidoreductase activity											EC:1.1.99.28|KEGG_REACTION:R00874|RHEA:20637|MetaCyc:1.1.99.28-RXN		molecular_function											owl:Class	
GO:0047021	biolink:NamedThing	15-hydroxyprostaglandin dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H(+) + NADPH.	got7fsn_ti	(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity|NADP-linked 15-hydroxyprostaglandin dehydrogenase|type II 15-hydroxyprostaglandin dehydrogenase activity|NADP-dependent 15-hydroxyprostaglandin dehydrogenase|NADP-specific 15-hydroxyprostaglandin dehydrogenase											EC:1.1.1.197|MetaCyc:1.1.1.197-RXN|RHEA:11636|KEGG_REACTION:R04552		molecular_function											owl:Class	
GO:0102088	biolink:NamedThing	N-(4-hydroxybenzoyl)-L-glutamate synthetase activity	Catalysis of the reaction: 4-hydroxybenzoic acid + L-glutamate + ATP <=> H+ + N-(4-hydroxybenzoyl)-L-glutamate + AMP + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10887		molecular_function											owl:Class	
GO:0048466	biolink:NamedThing	androecium development	The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0009754	biolink:NamedThing	detection of jasmonic acid stimulus	The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule.	got7fsn_ti	perception of jasmonic acid stimulus													biological_process											owl:Class	
GO:0046203	biolink:NamedThing	spermidine catabolic process	The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	got7fsn_ti	spermidine degradation|spermidine catabolism|spermidine breakdown													biological_process											owl:Class	
GO:0010111	biolink:NamedThing	glyoxysome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway.	got7fsn_ti	glyoxysome organization and biogenesis|glyoxysome organisation													biological_process											owl:Class	
GO:0031885	biolink:NamedThing	type 1 member 2 taste receptor binding	Binding to a type 1 member 2 taste receptor.	got7fsn_ti	type 1 member 2 taste receptor ligand													molecular_function											owl:Class	
GO:0051063	biolink:NamedThing	CDP reductase activity	Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.	got7fsn_ti	CDP reduction											MetaCyc:CDPREDUCT-RXN		molecular_function											owl:Class	
GO:0021718	biolink:NamedThing	superior olivary nucleus development	The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	got7fsn_ti	superior olive development													biological_process											owl:Class	
GO:0031825	biolink:NamedThing	type 1F serotonin receptor binding	Binding to a type 1F serotonin receptor.	got7fsn_ti	5-hydroxytryptamine 1F receptor binding|type 1F serotonin receptor ligand													molecular_function											owl:Class	
GO:0102848	biolink:NamedThing	1-18:2-2-18:2-digalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8310|EC:1.14.19.35		molecular_function											owl:Class	
GO:0019546	biolink:NamedThing	arginine deiminase pathway	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.	got7fsn_ti												MetaCyc:ARGDEGRAD-PWY		biological_process											owl:Class	
GO:0071925	biolink:NamedThing	thymic stromal lymphopoietin production	The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	TSLP production						mah	2010-09-28T11:38:55Z						biological_process											owl:Class	
GO:0043866	biolink:NamedThing	adenylyl-sulfate reductase (thioredoxin) activity	Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin.	got7fsn_ti	AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)|thioredoxin-dependent 5'-adenylylsulfate reductase activity|AMP, sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)											EC:1.8.4.10|RHEA:21976		molecular_function											owl:Class	
GO:0102684	biolink:NamedThing	L-phenylalanine N-monooxygenase activity	Catalysis of the reaction: L-phenylalanine  + 2 NADPH + 2 O2 + 2 H+ <=> (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide.	got7fsn_ti												EC:1.14.14.40|MetaCyc:RXN-4602|RHEA:33263		molecular_function											owl:Class	
GO:0140105	biolink:NamedThing	interleukin-10-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-10 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	IL-10-mediated signaling pathway|interleukin-10-mediated signalling pathway						pg	2017-09-22T16:04:42Z						biological_process											owl:Class	
GO:1990393	biolink:NamedThing	3M complex	A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity.	got7fsn_ti							sp	2014-06-05T06:40:49Z						cellular_component											owl:Class	
GO:0047934	biolink:NamedThing	glucose 1-dehydrogenase (NAD+) activity	Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH.	got7fsn_ti	D-glucose:NAD+ 1-oxidoreductase activity|D-aldohexose dehydrogenase activity|D-glucose:NAD oxidoreductase activity											RHEA:14293|MetaCyc:GLUCOSE-1-DEHYDROGENASE-NAD+-RXN|EC:1.1.1.118		molecular_function											owl:Class	
GO:0140306	biolink:NamedThing	lipoprotein releasing activity	The activity of recognizing mature outer membrane lipoproteins in the inner membrane and releasing from the inner membrane so that they can be transported across the periplasmic space to their target location, the outer membrane. This function exists in diderm bacteria, mediated by the LolCDE complex.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17058					pg	2019-03-22T14:25:43Z						molecular_function											owl:Class	
GO:0102285	biolink:NamedThing	1-deoxy-11-oxopentalenate oxygenase activity	Catalysis of the reaction: 1-deoxy-11-oxopentalenate + O2 + NADPH + H+ = pentalenolactone D + H2O + NADP.	got7fsn_ti												EC:1.14.13.170|RHEA:34635|MetaCyc:RXN-12654		molecular_function											owl:Class	
GO:0030346	biolink:NamedThing	protein phosphatase 2B binding	Binding to a protein phosphatase 2B.	got7fsn_ti	protein phosphatase 3 binding|calcineurin binding													molecular_function											owl:Class	
GO:0098761	biolink:NamedThing	cellular response to interleukin-7	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.	got7fsn_ti	cellular response to IL-7													biological_process											owl:Class	
GO:0140225	biolink:NamedThing	DNA topoisomerase III-beta-TDRD3 complex	A protein complex that has DNA topoisomerase type I and RNA topoisomerase activities.	got7fsn_ti	Top3-beta-TDRD3 complex						pg	2018-05-29T10:05:33Z						cellular_component											owl:Class	
GO:0001223	biolink:NamedThing	transcription coactivator binding	Binding to a transcription coactivator, a protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.	got7fsn_ti	RNA polymerase II transcription coactivator binding	https://github.com/geneontology/go-ontology/issues/19354					krc	2012-04-16T03:30:16Z			GO:0001225			molecular_function											owl:Class	
GO:0102546	biolink:NamedThing	mannosylglycerate hydrolase activity	Catalysis of the reaction: H2O + 2-(alpha-D-mannosyl)-D-glycerate <=> alpha-D-mannose + D-glycerate.	got7fsn_ti												MetaCyc:RXN-14900|RHEA:58456		molecular_function											owl:Class	
GO:1990327	biolink:NamedThing	collagen type XXV trimer	A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane.	got7fsn_ti							bhm	2014-03-17T09:28:50Z						cellular_component											owl:Class	
GO:0031680	biolink:NamedThing	G-protein beta/gamma-subunit complex	The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.	got7fsn_ti	heterotrimeric G-protein GTPase, beta-subunit|G-beta/G-gamma complex				See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'.									cellular_component											owl:Class	
GO:0018656	biolink:NamedThing	phenanthrene 3,4-monooxygenase activity	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide.	got7fsn_ti												EC:1.14.13.-|UM-BBD_reactionID:r0508		molecular_function											owl:Class	
GO:1990524	biolink:NamedThing	INA complex	A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p.	got7fsn_ti	INAC						jl	2014-11-03T16:03:39Z						cellular_component											owl:Class	
GO:0061690	biolink:NamedThing	lipoamidase activity	Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein.	got7fsn_ti	lipoyl-X-hydrolase						dph	2015-05-05T10:06:49Z				MetaCyc:RXN-13031		molecular_function											owl:Class	
GO:0046998	biolink:NamedThing	(S)-usnate reductase activity	Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH.	got7fsn_ti	L-usnic acid dehydrogenase activity|reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming)											EC:1.1.1.199|KEGG_REACTION:R07345|RHEA:21876|MetaCyc:1.1.1.199-RXN		molecular_function											owl:Class	
GO:0044245	biolink:NamedThing	polysaccharide digestion	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0046095	biolink:NamedThing	deoxyinosine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside.	got7fsn_ti	deoxyinosine synthesis|deoxyinosine anabolism|deoxyinosine biosynthesis|deoxyinosine formation													biological_process											owl:Class	
GO:0047727	biolink:NamedThing	isobutyryl-CoA mutase activity	Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA.	got7fsn_ti	2-methylpropanoyl-CoA CoA-carbonylmutase activity|isobutyryl coenzyme A mutase activity|butyryl-CoA:isobutyryl-CoA mutase activity											MetaCyc:ISOBUTYRYL-COA-MUTASE-RXN|RHEA:13141|EC:5.4.99.13|KEGG_REACTION:R01181		molecular_function											owl:Class	
GO:0044286	biolink:NamedThing	peg and socket contact	A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells.	got7fsn_ti	ball and socket contact						jl	2010-02-02T10:15:27Z				NIF_Subcellular:sao1943947957		cellular_component											owl:Class	
GO:0034817	biolink:NamedThing	cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity	Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-.	got7fsn_ti												UM-BBD_reactionID:r1144		molecular_function											owl:Class	
GO:0006577	biolink:NamedThing	amino-acid betaine metabolic process	The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.	got7fsn_ti	betaine metabolic process|betaine metabolism													biological_process											owl:Class	
GO:0031799	biolink:NamedThing	type 2 metabotropic glutamate receptor binding	Binding to a type 2 metabotropic glutamate receptor.	got7fsn_ti	type 2 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0034516	biolink:NamedThing	response to vitamin B6	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0015473	biolink:NamedThing	fimbrial usher porin activity	A porin that acts in the assembly of fimbria together with fimbrial chaperone.	got7fsn_ti														molecular_function											owl:Class	
GO:0047529	biolink:NamedThing	2,3-dimethylmalate lyase activity	Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate.	got7fsn_ti	(2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)|(2R,3S)-2,3-dimethylmalate pyruvate-lyase activity|2,3-dimethylmalate pyruvate-lyase activity											KEGG_REACTION:R01355|RHEA:10472|EC:4.1.3.32|MetaCyc:23-DIMETHYLMALATE-LYASE-RXN		molecular_function											owl:Class	
GO:0004090	biolink:NamedThing	carbonyl reductase (NADPH) activity	Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.	got7fsn_ti	NADPH-dependent carbonyl reductase activity|xenobiotic ketone reductase activity|NADPH2-dependent carbonyl reductase activity|aldehyde reductase 1|secondary-alcohol:NADP+ oxidoreductase activity|aldehyde reductase I activity|ALR3|nonspecific NADPH-dependent carbonyl reductase activity|prostaglandin 9-ketoreductase activity|carbonyl reductase activity											EC:1.1.1.184|RHEA:19257|Reactome:R-HSA-8937419|MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN		molecular_function											owl:Class	
GO:0010573	biolink:NamedThing	vascular endothelial growth factor production	The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	VEGF production													biological_process											owl:Class	
GO:0007387	biolink:NamedThing	anterior compartment pattern formation	The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.	got7fsn_ti	anterior compartment pattern specification													biological_process											owl:Class	
GO:0097692	biolink:NamedThing	histone H3-K4 monomethylation	The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone.	got7fsn_ti							pr	2015-11-05T11:23:15Z						biological_process											owl:Class	
GO:0031691	biolink:NamedThing	alpha-1A adrenergic receptor binding	Binding to an alpha-1A adrenergic receptor.	got7fsn_ti	alpha-1A adrenergic receptor ligand													molecular_function											owl:Class	
GO:0030110	biolink:NamedThing	HLA-C specific inhibitory MHC class I receptor activity	Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.	got7fsn_ti														molecular_function											owl:Class	
GO:0032616	biolink:NamedThing	interleukin-13 production	The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-13 biosynthetic process|IL-13 production|interleukin-13 secretion										GO:0072611|GO:0042231			biological_process											owl:Class	
GO:0034291	biolink:NamedThing	canonical holin activity	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting channel activity directly allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell.	got7fsn_ti														molecular_function											owl:Class	
GO:0042018	biolink:NamedThing	interleukin-22 receptor activity	Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	IL-22 receptor activity|IL-22R													molecular_function											owl:Class	
GO:0102384	biolink:NamedThing	19-O-beta-glucopyranosyl-steviol glucosyltransferase activity	Catalysis of the reaction: 19-O-beta-glucopyranosyl-steviol + UDP-alpha-D-glucose <=> rubusoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13521		molecular_function											owl:Class	
GO:0018773	biolink:NamedThing	acetylpyruvate hydrolase activity	Catalysis of the reaction: acetylpyruvate + H(2)O = acetate + H(+) + pyruvate.	got7fsn_ti	2,4-dioxopentanoate acetylhydrolase activity											RHEA:16097|MetaCyc:ACETYLPYRUVATE-HYDROLASE-RXN|EC:3.7.1.6|UM-BBD_reactionID:r0095|KEGG_REACTION:R00324		molecular_function											owl:Class	
GO:0052748	biolink:NamedThing	baicalin beta-D-glucuronidase activity	Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate.	got7fsn_ti	baicalinase activity|5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase activity						ai	2011-09-21T12:58:43Z				MetaCyc:RXN-11760|EC:3.2.1.167|KEGG_REACTION:R09533|RHEA:28130		molecular_function											owl:Class	
GO:0045352	biolink:NamedThing	interleukin-1 type I receptor antagonist activity	Blocks the binding of interleukin-1 to interleukin-1 type I receptors.	got7fsn_ti	IL-1ra type I													molecular_function											owl:Class	
GO:0039623	biolink:NamedThing	T=25 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres.	got7fsn_ti							bf	2012-07-18T02:21:43Z				VZ:810		cellular_component											owl:Class	
GO:0030625	biolink:NamedThing	U11 snRNA binding	Binding to a U11 small nuclear RNA (U11 snRNA).	got7fsn_ti														molecular_function											owl:Class	
GO:0050488	biolink:NamedThing	ecdysteroid UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.	got7fsn_ti	ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity										GO:0050489			molecular_function											owl:Class	
GO:0018028	biolink:NamedThing	peptidyl-lysine myristoylation	The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine.	got7fsn_ti	peptidyl-lysine myristylation											RESID:AA0078		biological_process											owl:Class	
GO:0034652	biolink:NamedThing	extrachromosomal circular DNA localization involved in cell aging	A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging.	got7fsn_ti	extrachromosomal circular DNA localization during cell ageing|extrachromosomal circular DNA localisation involved in cell aging|extrachromosomal circular DNA localization during cell aging				Note that the term string was changed to be consistent with placement of this term in cell aging hierarchy.									biological_process											owl:Class	
GO:0001301	biolink:NamedThing	progressive alteration of chromatin involved in cell aging	Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype.	got7fsn_ti	progressive alteration of chromatin during cell ageing|progressive alteration of chromatin during cell aging|age-dependent accumulation of genetic damage													biological_process											owl:Class	
GO:0030980	biolink:NamedThing	alpha-glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of alpha-glucans.	got7fsn_ti	alpha-glucan degradation|alpha-glucan breakdown|alpha-glucan catabolism													biological_process											owl:Class	
GO:0102629	biolink:NamedThing	patuletin 3'-O-methyltransferase activity	Catalysis of the reaction: patuletin + S-adenosyl-L-methionine  <=> quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-15534		molecular_function											owl:Class	
GO:0018466	biolink:NamedThing	limonene-1,2-diol dehydrogenase activity	Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene.	got7fsn_ti												EC:1.1.99.-|UM-BBD_reactionID:r0735		molecular_function											owl:Class	
GO:0034886	biolink:NamedThing	gamma-aminovinylacetate deaminase activity	Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3.	got7fsn_ti												EC:3.5.99.-|UM-BBD_reactionID:r1351		molecular_function											owl:Class	
GO:1990567	biolink:NamedThing	DPS complex	A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22.	got7fsn_ti							al	2014-11-27T09:56:18Z						cellular_component											owl:Class	
GO:0015946	biolink:NamedThing	methanol oxidation	The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M.	got7fsn_ti												MetaCyc:CO2FORM-PWY		biological_process											owl:Class	
GO:0015945	biolink:NamedThing	methanol metabolic process	The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.	got7fsn_ti	methanol metabolism													biological_process											owl:Class	
GO:0102700	biolink:NamedThing	alpha-thujene synthase activity	Catalysis of the reaction: geranyl diphosphate(3-) <=> alpha-thujene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-5105		molecular_function											owl:Class	
GO:0120203	biolink:NamedThing	rod photoreceptor disc lumen	The volume enclosed by the membrane of a rod photoreceptor cell disc membrane.	got7fsn_ti							krc	2019-05-07T23:49:50Z						cellular_component											owl:Class	
GO:0004719	biolink:NamedThing	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester.	got7fsn_ti	L-aspartyl/L-isoaspartyl protein methyltransferase activity|L-isoaspartyl protein carboxyl methyltransferase activity|protein L-isoaspartate methyltransferase activity|protein D-aspartate methyltransferase activity|D-aspartyl/L-isoaspartyl methyltransferase activity|protein-L-isoaspartate O-methyltransferase activity|protein-L-isoaspartate(D-aspartate) O-methyltransferase activity|L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase activity|protein O-methyltransferase (L-isoaspartate)|S-adenosyl-L-methionine:protein-L-isoaspartate O-methyltransferase activity|protein (D-aspartate) methyltransferase activity|protein-beta-aspartate O-methyltransferase activity|protein L-isoaspartyl methyltransferase activity|protein beta-aspartate O-methyltransferase activity											RHEA:12705|Reactome:R-HSA-5676966|EC:2.1.1.77|MetaCyc:2.1.1.77-RXN		molecular_function											owl:Class	
GO:0097271	biolink:NamedThing	protein localization to bud neck	A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.	got7fsn_ti	protein localization to cellular bud neck|protein localisation to bud neck						pr	2012-03-20T03:39:20Z						biological_process											owl:Class	
GO:0097266	biolink:NamedThing	phenylacetyl-CoA 1,2-epoxidase activity	Catalysis of the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+).	got7fsn_ti	phenylacetyl-CoA monooxygenase activity|phenylacetyl-CoA epoxidase activity|ring 1,2-phenylacetyl-CoA epoxidase activity						pr	2012-03-13T09:22:47Z				RHEA:32171|EC:1.14.13.149|KEGG_REACTION:R09838		molecular_function											owl:Class	
GO:0047392	biolink:NamedThing	CMP-N-acylneuraminate phosphodiesterase activity	Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP.	got7fsn_ti	CMP-N-acetylneuraminate hydrolase activity|cytidine monophosphosialic hydrolase activity|CMP-N-acylneuraminate N-acylneuraminohydrolase activity|CMP-sialate hydrolase activity|CMP-N-acylneuraminic acid hydrolase activity|cytidine monophosphate-N-acetylneuraminic acid hydrolase activity|CMP-sialic acid hydrolase activity|cytidine monophosphosialate hydrolase activity											RHEA:20185|MetaCyc:3.1.4.40-RXN|EC:3.1.4.40		molecular_function											owl:Class	
GO:0018693	biolink:NamedThing	ethylbenzene hydroxylase activity	Catalysis of the reaction: A + ethylbenzene + H(2)O = (S)-1-phenylethanol + AH(2).	got7fsn_ti	ethylbenzene:(acceptor) oxidoreductase activity|ethylbenzene dehydrogenase activity											KEGG_REACTION:R05745|RHEA:17897|MetaCyc:RXN-1301|UM-BBD_reactionID:r0234|EC:1.17.99.2		molecular_function											owl:Class	
GO:1990795	biolink:NamedThing	rod bipolar cell terminal bouton	A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer.	got7fsn_ti							sl	2015-07-09T21:11:53Z						cellular_component											owl:Class	
GO:0031704	biolink:NamedThing	apelin receptor binding	Binding to an apelin receptor.	got7fsn_ti	APJ receptor binding|apelin receptor ligand										GO:0042569			molecular_function											owl:Class	
GO:0050766	biolink:NamedThing	positive regulation of phagocytosis	Any process that activates or increases the frequency, rate or extent of phagocytosis.	got7fsn_ti	up regulation of phagocytosis|up-regulation of phagocytosis|upregulation of phagocytosis|stimulation of phagocytosis|activation of phagocytosis													biological_process											owl:Class	
GO:0001065	biolink:NamedThing	mitochondrial single subunit type RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti							krc	2010-10-19T03:50:51Z						molecular_function											owl:Class	
GO:0043365	biolink:NamedThing	[formate-C-acetyltransferase]-activating enzyme activity	Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical.	got7fsn_ti	formate-C-acetyltransferase-activating enzyme|PFL activase activity|PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving) activity|[pyruvate formate-lyase]-activating enzyme activity|pyruvate formate-lyase-activating enzyme|formate acetyltransferase activating enzyme activity|formate C-acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)|formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving) activity	https://github.com/geneontology/go-ontology/issues/14190									GO:0008862	EC:1.97.1.4|RHEA:19225|MetaCyc:TDCEACT-RXN		molecular_function											owl:Class	
GO:0018568	biolink:NamedThing	3,4-dihydroxyphenanthrene dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate.	got7fsn_ti												UM-BBD_reactionID:r0501|EC:1.13.11.-		molecular_function											owl:Class	
GO:0044817	biolink:NamedThing	hydrogen generation via biophotolysis	The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae.	got7fsn_ti	hydrogen biosynthesis via biophotolysis						jl	2013-10-22T14:36:54Z						biological_process											owl:Class	
GO:0004490	biolink:NamedThing	methylglutaconyl-CoA hydratase activity	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O.	got7fsn_ti	(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase activity|methylglutaconyl coenzyme A hydratase activity|methylglutaconase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)|3-methylglutaconyl CoA hydratase activity											EC:4.2.1.18|KEGG_REACTION:R02085|RHEA:21536|MetaCyc:METHYLGLUTACONYL-COA-HYDRATASE-RXN|Reactome:R-HSA-70785		molecular_function											owl:Class	
GO:0018659	biolink:NamedThing	4-hydroxybenzoate 3-monooxygenase activity	Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O.	got7fsn_ti	4-hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating)|p-hydroxybenzoic acid hydrolase activity|para-hydroxybenzoate hydroxylase activity|p-hydroxybenzoic acid hydroxylase activity|4-hydroxybenzoate monooxygenase activity|p-hydroxybenzoic hydroxylase activity|p-hydroxybenzoate hydrolyase activity|p-hydroxybenzoate-3-hydroxylase activity|4-hydroxybenzoate 3-hydroxylase activity|p-hydroxybenzoate hydroxylase activity											UM-BBD_reactionID:r0109|MetaCyc:4-HYDROXYBENZOATE-3-MONOOXYGENASE-RXN|EC:1.14.13.2		molecular_function											owl:Class	
GO:0102618	biolink:NamedThing	oryzalexin B synthase activity	Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin B + H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-15466		molecular_function											owl:Class	
GO:0102828	biolink:NamedThing	stachyose galactinol:verbascose galactosyltransferase activity	Catalysis of the reaction: stachyose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> verbascose + myo-inositol.	got7fsn_ti												MetaCyc:RXN-8284		molecular_function											owl:Class	
GO:0055012	biolink:NamedThing	ventricular cardiac muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.	got7fsn_ti	ventricular heart muscle cell differentiation|ventricular cardiomyocyte differentiation													biological_process											owl:Class	
GO:0070313	biolink:NamedThing	RGS6-DNMT1-DMAP1 complex	A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.	got7fsn_ti														cellular_component											owl:Class	
GO:0008679	biolink:NamedThing	2-hydroxy-3-oxopropionate reductase activity	Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+.	got7fsn_ti	(R)-glycerate:NAD(P)+ oxidoreductase activity|tartronate semialdehyde reductase (NADPH) activity											RHEA:18841|MetaCyc:TSA-REDUCT-RXN|EC:1.1.1.60		molecular_function											owl:Class	
GO:0009104	biolink:NamedThing	lipopolysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.	got7fsn_ti	lipopolysaccharide breakdown|LPS catabolic process|lipopolysaccharide degradation|lipopolysaccharide catabolism													biological_process											owl:Class	
GO:0034876	biolink:NamedThing	isonicotinic acid hydrazide hydrolase activity	Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine.	got7fsn_ti												UM-BBD_reactionID:r1336		molecular_function											owl:Class	
GO:0102738	biolink:NamedThing	(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate <=> gibberellin A37 + carbon dioxide + succinate.	got7fsn_ti												MetaCyc:RXN-7589		molecular_function											owl:Class	
GO:0046201	biolink:NamedThing	cyanate biosynthetic process	The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid.	got7fsn_ti	cyanate synthesis|cyanate anabolism|cyanate formation|cyanate biosynthesis													biological_process											owl:Class	
GO:0019335	biolink:NamedThing	3-methylquinoline catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.	got7fsn_ti	3-methylquinoline breakdown|3-methylquinoline degradation|3-methylquinoline catabolism											MetaCyc:PWY-721		biological_process											owl:Class	
GO:0005144	biolink:NamedThing	interleukin-13 receptor binding	Binding to an interleukin-13 receptor.	got7fsn_ti	IL-13|interleukin-13 receptor ligand													molecular_function											owl:Class	
GO:0097739	biolink:NamedThing	negative regulation of ferrichrome biosynthetic process in response to iron	Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus.	got7fsn_ti							pr	2016-10-18T17:00:24Z						biological_process											owl:Class	
GO:1905569	biolink:NamedThing	negative regulation of ferrichrome biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process.	got7fsn_ti	down-regulation of ferrichrome anabolism|down-regulation of ferrichrome biosynthetic process|down regulation of ferrichrome formation|downregulation of ferrichrome formation|down regulation of ferrichrome biosynthetic process, peptide formation|negative regulation of ferrichrome biosynthetic process, peptide modification|inhibition of ferrichrome biosynthetic process, peptide formation|down regulation of ferrichrome anabolism|down-regulation of ferrichrome formation|negative regulation of ferrichrome synthesis|downregulation of ferrichrome biosynthesis|negative regulation of ferrichrome biosynthesis|inhibition of ferrichrome biosynthesis|down regulation of ferrichrome biosynthetic process|down regulation of ferrichrome biosynthetic process, peptide modification|inhibition of ferrichrome anabolism|downregulation of ferrichrome biosynthetic process|negative regulation of ferrichrome biosynthetic process, peptide formation|downregulation of ferrichrome biosynthetic process, peptide formation|down-regulation of ferrichrome synthesis|negative regulation of ferrichrome anabolism|inhibition of ferrichrome formation|down-regulation of ferrichrome biosynthetic process, peptide formation|inhibition of ferrichrome biosynthetic process|down regulation of ferrichrome synthesis|inhibition of ferrichrome biosynthetic process, peptide modification|negative regulation of ferrichrome formation|down-regulation of ferrichrome biosynthesis|inhibition of ferrichrome synthesis|down regulation of ferrichrome biosynthesis|downregulation of ferrichrome synthesis|down-regulation of ferrichrome biosynthetic process, peptide modification|downregulation of ferrichrome biosynthetic process, peptide modification|downregulation of ferrichrome anabolism						pr	2016-10-18T14:49:08Z						biological_process											owl:Class	
GO:0034945	biolink:NamedThing	2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity	Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0987|EC:2.3.1.-		molecular_function											owl:Class	
GO:0102751	biolink:NamedThing	UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+.	got7fsn_ti												MetaCyc:RXN-7667|RHEA:56560|EC:2.4.1.186		molecular_function											owl:Class	
GO:0047015	biolink:NamedThing	3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity	Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.	got7fsn_ti	2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity|2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity|(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity|2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity											MetaCyc:1.1.1.178-RXN|RHEA:13281|EC:1.1.1.178		molecular_function											owl:Class	
GO:0106343	biolink:NamedThing	glutarate dioxygenase activity	Catalysis of the reaction glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2.	got7fsn_ti							hjd	2020-11-17T18:04:10Z				EC:1.14.11.64|RHEA:13821		molecular_function											owl:Class	
GO:0090438	biolink:NamedThing	camelliol C synthase activity	Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C.	got7fsn_ti	(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming)						tb	2012-08-08T15:41:45Z						molecular_function											owl:Class	
GO:0140682	biolink:NamedThing	histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.	got7fsn_ti	histone H3K4me2 demethylase activity|histone H3K4me demethylase activity	https://github.com/geneontology/go-ontology/issues/21089					pg	2021-07-08T15:45:22Z				EC:1.14.99.66|RHEA:60244		molecular_function											owl:Class	
GO:0034690	biolink:NamedThing	integrin alphaD-beta2 complex	An integrin complex that comprises one alphaD subunit and one beta2 subunit.	got7fsn_ti	alphaD-beta2 integrin complex|Itgad-Itgb2 complex													cellular_component											owl:Class	
GO:0103006	biolink:NamedThing	9,10-dihydroxystearate hydroxylase activity	Catalysis of the reaction: H+ + (9R,10S)-dihydroxystearate + O2 + NADPH <=> 9,10,18-trihydroxystearate + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-9807		molecular_function											owl:Class	
GO:0019579	biolink:NamedThing	aldaric acid catabolic process	The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.	got7fsn_ti	aldaric acid degradation|aldaric acid breakdown|aldaric acid catabolism													biological_process											owl:Class	
GO:0021617	biolink:NamedThing	glossopharyngeal nerve structural organization	The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	got7fsn_ti	CN IX structural organization|glossopharyngeal nerve structural organisation													biological_process											owl:Class	
GO:0047344	biolink:NamedThing	glucose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose.	got7fsn_ti	GDP-glucose pyrophosphorylase activity|GTP:glucose-1-phosphate guanylyltransferase activity|GDP glucose pyrophosphorylase activity|GDP-glucose diphosphorylase activity|GTP:alpha-D-glucose-1-phosphate guanylyltransferase activity|guanosine diphosphoglucose pyrophosphorylase activity											RHEA:10708|KEGG_REACTION:R00954|EC:2.7.7.34|MetaCyc:2.7.7.34-RXN		molecular_function											owl:Class	
GO:0031042	biolink:NamedThing	O-glycan processing, core 6	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc.	got7fsn_ti														biological_process											owl:Class	
GO:0018081	biolink:NamedThing	peptide cross-linking via lanthionine or 3-methyl-lanthionine	The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process.	got7fsn_ti	peptide cross-linking via the thioethers lanthionine or 3-methyl-lanthionine|peptide cross-linking via the thiolethers lanthionine or 3-methyl-lanthionine											RESID:AA0111|RESID:AA0110|RESID:AA0112		biological_process											owl:Class	
GO:0047059	biolink:NamedThing	polyvinyl alcohol dehydrogenase (cytochrome) activity	Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+.	got7fsn_ti	PVA dehydrogenase activity|polyvinyl alcohol:ferricytochrome-c oxidoreductase activity|polyvinyl-alcohol:(acceptor) oxidoreductase activity|polyvinyl-alcohol:acceptor oxidoreductase activity				Formerly EC:1.1.99.23.							EC:1.1.2.6|KEGG_REACTION:R03136|MetaCyc:RXN-11316|RHEA:20157		molecular_function											owl:Class	
GO:0003131	biolink:NamedThing	mesodermal-endodermal cell signaling	Any process that mediates the transfer of information from mesodermal cells to endodermal cells.	got7fsn_ti	mesodermal-endodermal cell signalling						tb	2009-09-22T03:07:34Z						biological_process											owl:Class	
GO:0031083	biolink:NamedThing	BLOC-1 complex	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0097255	biolink:NamedThing	R2TP complex	A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others.	got7fsn_ti							pr	2012-03-06T11:16:33Z						cellular_component											owl:Class	
GO:0050030	biolink:NamedThing	L-pipecolate dehydrogenase activity	Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.	got7fsn_ti	L-pipecolate:(acceptor) 1,6-oxidoreductase activity|L-pipecolate:acceptor 1,6-oxidoreductase activity											MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN|EC:1.5.99.3|RHEA:19777		molecular_function											owl:Class	
GO:0047959	biolink:NamedThing	glycine dehydrogenase (cytochrome) activity	Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c.	got7fsn_ti	glycine-cytochrome c reductase activity|glycine:ferricytochrome-c oxidoreductase (deaminating)|reductase, glycine-cytochrome c											RHEA:16909|MetaCyc:GLYCINE-DEHYDROGENASE-CYTOCHROME-RXN|EC:1.4.2.1		molecular_function											owl:Class	
GO:0034836	biolink:NamedThing	6-hydroxy-2-mercaptobenzothiazole monooxygenase activity	Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole.	got7fsn_ti												UM-BBD_reactionID:r1181|EC:1.13.12.-		molecular_function											owl:Class	
GO:0016155	biolink:NamedThing	formyltetrahydrofolate dehydrogenase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH.	got7fsn_ti	10-formyl-H4folate dehydrogenase activity|10-formyl-H2PtGlu:NADP oxidoreductase activity|10-formyltetrahydrofolate dehydrogenase activity|10-formyl tetrahydrofolate:NADP oxidoreductase activity|10-formyltetrahydrofolate:NADP+ oxidoreductase activity|N10-formyltetrahydrofolate dehydrogenase activity											RHEA:10180|EC:1.5.1.6|KEGG_REACTION:R00941|MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0004304	biolink:NamedThing	estrone sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate.	got7fsn_ti	3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase activity|estrogen sulfotransferase|estrogen sulphotransferase activity|3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase activity|estrone sulphotransferase activity|3'-phosphoadenylylsulfate:oestrone sulfotransferase activity|oestrogen sulphotransferase activity											EC:2.8.2.4|RHEA:15973|MetaCyc:ESTRONE-SULFOTRANSFERASE-RXN|Reactome:R-HSA-176664		molecular_function											owl:Class	
GO:0070617	biolink:NamedThing	negative regulation of thiamine diphosphate biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.	got7fsn_ti	negative regulation of thiamine diphosphate synthesis|down regulation of thiamine diphosphate biosynthetic process|inhibition of thiamine diphosphate biosynthetic process|negative regulation of thiamine diphosphate anabolism|downregulation of thiamine diphosphate biosynthetic process|negative regulation of thiamin diphosphate biosynthetic process|negative regulation of thiamine diphosphate biosynthesis|down-regulation of thiamine diphosphate biosynthetic process|negative regulation of thiamine diphosphate formation						mah	2009-04-29T03:39:48Z						biological_process											owl:Class	
GO:0060045	biolink:NamedThing	positive regulation of cardiac muscle cell proliferation	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.	got7fsn_ti	positive regulation of heart muscle cell proliferation													biological_process											owl:Class	
GO:0030909	biolink:NamedThing	non-intein-mediated protein splicing	The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins.	got7fsn_ti														biological_process											owl:Class	
GO:0033818	biolink:NamedThing	beta-ketoacyl-acyl-carrier-protein synthase III activity	Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2.	got7fsn_ti	beta-ketoacyl-ACP synthase III activity|acetyl-CoA:malonyl-acyl-carrier-protein C-acyltransferase activity|KAS III|beta-ketoacyl (acyl carrier protein) synthase III activity|3-ketoacyl-acyl carrier protein synthase III activity|KASIII|FabH|beta-ketoacyl-acyl carrier protein synthase III activity|3-oxoacyl:ACP synthase III activity											RHEA:12080|MetaCyc:2.3.1.180-RXN|EC:2.3.1.180		molecular_function											owl:Class	
GO:0036181	biolink:NamedThing	protein localization to linear element	A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase.	got7fsn_ti	protein localisation to linear element						bf	2012-03-30T04:14:17Z						biological_process											owl:Class	
GO:0043176	biolink:NamedThing	amine binding	Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group.	got7fsn_ti														molecular_function											owl:Class	
GO:0044586	biolink:NamedThing	cellotetraose binding	Binding to a cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.	got7fsn_ti							jl	2012-04-24T04:56:10Z						molecular_function											owl:Class	
GO:0034923	biolink:NamedThing	phenanthrene-4,5-dicarboxylate decarboxylase activity	Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2.	got7fsn_ti												UM-BBD_reactionID:r0937		molecular_function											owl:Class	
GO:0048292	biolink:NamedThing	isotype switching to IgD isotypes	The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.	got7fsn_ti	isotype switch recombination to IgD isotypes|class switching to IgD isotypes				Note that this term is to be used only for gene products involved in the expression of IgD through recombinational switching into the vestigial switch region at the 5' end of the IgD gene segment, rather than gene products involved in the expression of IgD through alternative splicing mechanisms.									biological_process											owl:Class	
GO:0016154	biolink:NamedThing	pyrimidine-nucleoside phosphorylase activity	Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.	got7fsn_ti	Py-NPase activity|pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity											MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN|EC:2.4.2.2		molecular_function											owl:Class	
GO:0010057	biolink:NamedThing	trichoblast fate specification	The process involved in the specification of a trichoblast.	got7fsn_ti														biological_process											owl:Class	
GO:0097126	biolink:NamedThing	cyclin B2-CDK1 complex	A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:46:17Z						cellular_component											owl:Class	
GO:0047088	biolink:NamedThing	dihydrosanguinarine 10-monooxygenase activity	Catalysis of the reaction: dihydrosanguinarine + H(+) + NADPH + O(2) = 10-hydroxydihydrosanguinarine + H(2)O + NADP(+).	got7fsn_ti	dihydrosanguinarine,NADPH:oxygen oxidoreductase (10-hydroxylating)|dihydrosanguinarine 10-hydroxylase activity											EC:1.14.14.100|KEGG_REACTION:R04702|RHEA:10528|MetaCyc:1.14.13.56-RXN		molecular_function											owl:Class	
GO:0018583	biolink:NamedThing	biphenyl-2,3-diol 1,2-dioxygenase activity	Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O.	got7fsn_ti	2,3-dihydroxybiphenyl dioxygenase activity|biphenyl-2,3-diol dioxygenase activity|2,3-dihydroxybiphenyl 1,2-dioxygenase activity|biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing)											RHEA:14413|EC:1.13.11.39|MetaCyc:BIPHENYL-23-DIOL-12-DIOXYGENASE-RXN|UM-BBD_enzymeID:e0127		molecular_function											owl:Class	
GO:0007638	biolink:NamedThing	mechanosensory behavior	Behavior that is dependent upon the sensation of a mechanical stimulus.	got7fsn_ti	mechanosensory behaviour|behavioral response to mechanical stimulus|behavioural response to mechanical stimulus													biological_process											owl:Class	
GO:0045131	biolink:NamedThing	pre-mRNA branch point binding	Binding to a pre-mRNA branch point sequence, located upstream of the 3' splice site.	got7fsn_ti														molecular_function											owl:Class	
GO:0050593	biolink:NamedThing	N-methylcoclaurine 3'-monooxygenase activity	Catalysis of the reaction: (S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+).	got7fsn_ti	(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating)|cytochrome P450 80B1 activity|(S)-N-methylcoclaurine 3'-hydroxylase activity|N-methylcoclaurine 3'-hydroxylase activity											MetaCyc:1.14.13.71-RXN|RHEA:16649|EC:1.14.14.102|KEGG_REACTION:R05732		molecular_function											owl:Class	
GO:0039606	biolink:NamedThing	suppression by virus of host translation initiation	Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein.	got7fsn_ti							bf	2012-07-05T04:44:10Z						biological_process											owl:Class	
GO:0016012	biolink:NamedThing	sarcoglycan complex	A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex.	got7fsn_ti	sarcoglycan-sarcospan complex													cellular_component											owl:Class	
GO:0023002	biolink:NamedThing	nuclear migration to embryo sac poles	Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell.	got7fsn_ti	nucleus migration to megagametophyte poles|nucleus migration to embryo sac poles|nucleus migration to female gametophyte poles|nuclear migration to megagametophyte poles|nuclear migration to female gametophyte poles													biological_process											owl:Class	
GO:1902728	biolink:NamedThing	positive regulation of growth factor dependent skeletal muscle satellite cell proliferation	Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.	got7fsn_ti							mr	2014-02-24T16:10:33Z						biological_process											owl:Class	
GO:1902724	biolink:NamedThing	positive regulation of skeletal muscle satellite cell proliferation	Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation.	got7fsn_ti	up regulation of satellite cell proliferation|up-regulation of satellite cell proliferation|upregulation of satellite cell proliferation|activation of satellite cell proliferation						mr	2014-02-24T16:09:56Z						biological_process											owl:Class	
GO:0090449	biolink:NamedThing	phloem glucosinolate loading	The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink.	got7fsn_ti							tb	2012-09-07T16:21:22Z						biological_process											owl:Class	
GO:1901349	biolink:NamedThing	glucosinolate transport	The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2012-09-07T22:44:34Z						biological_process											owl:Class	
GO:0009990	biolink:NamedThing	contact guidance	Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells.	got7fsn_ti														biological_process											owl:Class	
GO:0008362	biolink:NamedThing	chitin-based embryonic cuticle biosynthetic process	Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster.	got7fsn_ti	embryonic cuticle biosynthetic process|embryonic cuticle synthesis|embryonic cuticle formation|embryonic cuticle anabolism													biological_process											owl:Class	
GO:0015955	biolink:NamedThing	pyrimidine deoxyribonucleotide interconversion	The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.	got7fsn_ti														biological_process											owl:Class	
GO:0009219	biolink:NamedThing	pyrimidine deoxyribonucleotide metabolic process	The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine deoxyribonucleotide metabolism													biological_process											owl:Class	
GO:0140692	biolink:NamedThing	very long-chain fatty acid omega-hydroxylase activity	Catalysis of the reaction: an omega-methyl-very-long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an omega-hydroxy-very-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21925					pg	2021-08-05T07:41:17Z						molecular_function											owl:Class	
GO:0070242	biolink:NamedThing	thymocyte apoptotic process	Any apoptotic process in a thymocyte, an immature T cell located in the thymus.	got7fsn_ti	thymocyte apoptosis|immature T cell apoptosis				Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).									biological_process											owl:Class	
GO:0045720	biolink:NamedThing	negative regulation of integrin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.	got7fsn_ti	inhibition of integrin biosynthetic process|negative regulation of integrin biosynthesis|down regulation of integrin biosynthetic process|down-regulation of integrin biosynthetic process|downregulation of integrin biosynthetic process|negative regulation of integrin anabolism|negative regulation of integrin synthesis|negative regulation of integrin formation													biological_process											owl:Class	
GO:0042500	biolink:NamedThing	aspartic endopeptidase activity, intramembrane cleaving	Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.	got7fsn_ti					Note that although GO generally avoids the use of localization information in terms, in this case an exception was made. This is because the fact that the cleavage occurs within the membrane is integral to its function, as it is the only thing that distinguishes this group from other aspartic endopeptidases.							EC:3.4.23.-|Reactome:R-HSA-8863101		molecular_function											owl:Class	
GO:0070371	biolink:NamedThing	ERK1 and ERK2 cascade	An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.	got7fsn_ti	ERK1 and ERK2 signalling pathway|ERK1 cascade|MAPK1 cascade|ERK cascade|ERK2 cascade|MAPK3 cascade|extracellular signal-regulated kinase 1/2 cascade|extracellular signal-regulated kinase 1/2 (ERK1/2) cascade|ERK1 and ERK2 signaling pathway|ERK1/2 cascade				Note that this MAPKKK cascade is commonly referred to as the ERK pathway in the literature, but involves only ERK1 or ERK2 and should not be confused with cascades that involve other ERK kinases.									biological_process											owl:Class	
GO:0022023	biolink:NamedThing	radial glial cell fate commitment in forebrain	The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.	got7fsn_ti														biological_process											owl:Class	
GO:0102834	biolink:NamedThing	1-18:1-2-16:0-monogalactosyldiacylglycerol acyl-lipid omega-6 desaturase activity	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.23|MetaCyc:RXN-8294		molecular_function											owl:Class	
GO:0047390	biolink:NamedThing	glycerophosphocholine cholinephosphodiesterase activity	Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+).	got7fsn_ti	L-3-glycerylphosphinicocholine cholinephosphohydrolase activity|sn-glycero-3-phosphocholine cholinephosphohydrolase activity											RHEA:19545|Reactome:R-HSA-6814797|KEGG_REACTION:R02591|EC:3.1.4.38|MetaCyc:3.1.4.38-RXN		molecular_function											owl:Class	
GO:0043024	biolink:NamedThing	ribosomal small subunit binding	Binding to a small ribosomal subunit.	got7fsn_ti														molecular_function											owl:Class	
GO:0034710	biolink:NamedThing	inhibin complex binding	Binding to an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit.	got7fsn_ti														molecular_function											owl:Class	
GO:0043522	biolink:NamedThing	leucine zipper domain binding	Binding to a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns.	got7fsn_ti	leucine zipper binding													molecular_function											owl:Class	
GO:0050464	biolink:NamedThing	nitrate reductase (NADPH) activity	Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+.	got7fsn_ti	NADPH-nitrate reductase activity|nitrate reductase (NADPH2)|triphosphopyridine nucleotide-nitrate reductase activity|NADPH:nitrate reductase activity|NADPH:nitrate oxidoreductase activity|assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase activity|nitrate reductase (NADPH(2)) activity|assimilatory nitrate reductase activity|assimilatory NADPH-nitrate reductase activity|nitrite:NADP+ oxidoreductase activity											EC:1.7.1.3|RHEA:19061|MetaCyc:NITRATE-REDUCTASE-NADPH-RXN		molecular_function											owl:Class	
GO:0052580	biolink:NamedThing	(+)-pulegone reductase, (-)-menthone as substrate, activity	Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+.	got7fsn_ti	(-)-menthone:NADP+ oxidoreductase activity						ai	2010-08-09T04:33:53Z				EC:1.3.1.81|MetaCyc:RXN-5164		molecular_function											owl:Class	
GO:0005248	biolink:NamedThing	voltage-gated sodium channel activity	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage gated sodium channel activity|voltage-sensitive sodium channel|voltage-gated sodium ion channel activity|voltage-dependent sodium channel activity											Reactome:R-HSA-5576895		molecular_function											owl:Class	
GO:0005272	biolink:NamedThing	sodium channel activity	Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti												Reactome:R-HSA-3295580|Reactome:R-HSA-2730664		molecular_function											owl:Class	
GO:0008116	biolink:NamedThing	prostaglandin-I synthase activity	Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2).	got7fsn_ti	prostacycline synthetase activity|PGI(2) synthetase activity|cytochrome P450 CYP8A1|PGI2 synthetase activity|PGI(2) synthase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity|prostacyclin synthase activity|PGI2 synthase activity|prostagladin I2 synthetase activity											Reactome:R-HSA-76496|KEGG_REACTION:R02267|MetaCyc:PROSTAGLANDIN-I-SYNTHASE-RXN|EC:5.3.99.4|RHEA:23580		molecular_function											owl:Class	
GO:0043799	biolink:NamedThing	glycine oxidase activity	Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide.	got7fsn_ti	glycine:oxygen oxidoreductase (deaminating)											MetaCyc:RXN-8672|EC:1.4.3.19|MetaCyc:1.4.3.19-RXN|MetaCyc:RXN-8674|MetaCyc:RXN-8673		molecular_function											owl:Class	
GO:0071601	biolink:NamedThing	sphere organelle	A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins.	got7fsn_ti							mah	2010-02-04T04:26:41Z						cellular_component											owl:Class	
GO:0008806	biolink:NamedThing	carboxymethylenebutenolidase activity	Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate.	got7fsn_ti	maleylacetate enol-lactonase activity|4-carboxymethylenebut-2-en-4-olide lactonohydrolase activity|carboxymethylene butenolide hydrolase activity|dienelactone hydrolase activity										GO:0018735	RHEA:12372|EC:3.1.1.45|UM-BBD_enzymeID:e0066|MetaCyc:CARBOXYMETHYLENEBUTENOLIDASE-RXN		molecular_function											owl:Class	
GO:0003118	biolink:NamedThing	regulation of vasoconstriction by neuronal norepinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings.	got7fsn_ti	regulation of vasoconstriction by neuronal noradrenaline													biological_process											owl:Class	
GO:0008660	biolink:NamedThing	1-aminocyclopropane-1-carboxylate deaminase activity	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanate + NH(4)(+).	got7fsn_ti	1-aminocyclopropane carboxylic acid deaminase activity|1-aminocyclopropane-1-carboxylate endolyase (deaminating) activity|ACC deaminase activity|1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing)				Note that this function was formerly EC:4.1.99.4.						GO:0018806	UM-BBD_reactionID:r0357|EC:3.5.99.7|MetaCyc:4.1.99.4-RXN|RHEA:16933|KEGG_REACTION:R00997		molecular_function											owl:Class	
GO:0035746	biolink:NamedThing	granzyme A production	The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-03-17T02:39:11Z						biological_process											owl:Class	
GO:0047589	biolink:NamedThing	5-aminovalerate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate.	got7fsn_ti	delta-aminovalerate transaminase activity|5-aminopentanoate:2-oxoglutarate aminotransferase activity|delta-aminovalerate aminotransferase activity|5-aminovalerate aminotransferase activity											RHEA:10212|MetaCyc:VAGL-RXN|EC:2.6.1.48|KEGG_REACTION:R02274		molecular_function											owl:Class	
GO:0090614	biolink:NamedThing	5'-methylthioadenosine deaminase activity	Catalysis of the reaction: 5'methyl thioadenosine + H2O = 5'methyl thioinosine + NH3.	got7fsn_ti							tb	2014-10-23T15:59:38Z				RHEA:25025|EC:3.5.4.31		molecular_function											owl:Class	
GO:0060772	biolink:NamedThing	leaf phyllotactic patterning	The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.	got7fsn_ti							dph	2009-07-25T06:27:15Z						biological_process											owl:Class	
GO:0018835	biolink:NamedThing	carbon phosphorus lyase activity	Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).	got7fsn_ti											GO:0009456	EC:4.7.1.-		molecular_function											owl:Class	
GO:0036300	biolink:NamedThing	B cell receptor internalization	A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell.	got7fsn_ti	BCR receptor internalization|B cell receptor uptake of antigen|BCR endocytosis						bf	2012-08-07T11:24:20Z						biological_process											owl:Class	
GO:1902794	biolink:NamedThing	heterochromatin island assembly	The aggregation, arrangement and bonding together of a set of components to form a heterochromatin island.	got7fsn_ti	heterochromatin island formation						mah	2014-03-24T12:46:49Z						biological_process											owl:Class	
GO:0051796	biolink:NamedThing	negative regulation of timing of catagen	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.	got7fsn_ti	negative regulation of catagen|inhibition of catagen|down regulation of catagen|down-regulation of catagen|downregulation of catagen													biological_process											owl:Class	
GO:0102854	biolink:NamedThing	1-18:2-2-18:1-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8321		molecular_function											owl:Class	
GO:0018233	biolink:NamedThing	peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine	The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link.	got7fsn_ti												RESID:AA0109		biological_process											owl:Class	
GO:0097519	biolink:NamedThing	DNA recombinase complex	A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA.	got7fsn_ti							pr	2013-10-16T15:43:22Z						cellular_component											owl:Class	
GO:0070640	biolink:NamedThing	vitamin D3 metabolic process	The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.	got7fsn_ti	cholecalciferol metabolic process|vitamin D3 metabolism|calciol metabolic process						mah	2009-05-08T02:24:24Z						biological_process											owl:Class	
GO:0000001	biolink:NamedThing	mitochondrion inheritance	The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.	got7fsn_ti	mitochondrial inheritance													biological_process											owl:Class	
GO:0002278	biolink:NamedThing	eosinophil activation involved in immune response	The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	eosinophil activation during immune response													biological_process											owl:Class	
GO:0019920	biolink:NamedThing	peptidyl-1-thioglycine biosynthetic process, internal	The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide.	got7fsn_ti	peptidyl-1-thioglycine formation, internal|peptidyl-1-thioglycine anabolism, internal|peptidyl-1-thioglycine synthesis, internal											RESID:AA0265		biological_process											owl:Class	
GO:0098715	biolink:NamedThing	malonic acid import across plasma membrane	The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	malonate import into cell|malonic acid import into cell						pr	2012-10-30T15:33:37Z			GO:0097406			biological_process											owl:Class	
GO:0043115	biolink:NamedThing	precorrin-2 dehydrogenase activity	Catalysis of the reaction: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin.	got7fsn_ti	dihydrosirohydrochlorin dehydrogenase activity|CysG|precorrin-2:NAD+ oxidoreductase activity|1,3-dimethyluroporphyrinogen III dehydrogenase activity|Met8p|precorrin-2 oxidase activity|siroheme synthase activity|SirC											KEGG_REACTION:R03947|MetaCyc:DIMETHUROPORDEHYDROG-RXN|EC:1.3.1.76|RHEA:15613		molecular_function											owl:Class	
GO:0034846	biolink:NamedThing	naphthyl-2-methylene-succinyl-CoA lyase activity	Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r1259		molecular_function											owl:Class	
GO:0008965	biolink:NamedThing	phosphoenolpyruvate-protein phosphotransferase activity	Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine.	got7fsn_ti	enzyme I of the phosphotransferase system|phosphoenolpyruvate:protein-L-histidine Npi-phosphotransferase activity|phosphopyruvate--protein factor phosphotransferase activity|phosphopyruvate--protein phosphotransferase activity|phosphoenolpyruvate--protein phosphatase activity|phosphoenolpyruvate sugar phosphotransferase enzyme I activity|sugar--PEP phosphotransferase enzyme I activity|phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase activity											EC:2.7.3.9|MetaCyc:2.7.3.9-RXN|RHEA:23880		molecular_function											owl:Class	
GO:0061594	biolink:NamedThing	6-deoxy-6-sulfofructose kinase activity	Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP.	got7fsn_ti							dph	2014-02-10T09:59:26Z				EC:2.7.1.184|MetaCyc:RXN-15297|RHEA:40443		molecular_function											owl:Class	
GO:0031213	biolink:NamedThing	RSF complex	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters).	got7fsn_ti	remodeling and spacing factor complex													cellular_component											owl:Class	
GO:0033848	biolink:NamedThing	N2-(2-carboxyethyl)arginine synthase activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate.	got7fsn_ti	glyceraldehyde-3-phosphate:L-arginine 2-N-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity|CEAS|CEA synthetase activity|N2-(2-carboxyethyl)arginine synthetase activity|glyceraldehyde-3-phosphate:L-arginine N2-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity											EC:2.5.1.66|KEGG_REACTION:R05465|RHEA:10556|MetaCyc:2.5.1.66-RXN		molecular_function											owl:Class	
GO:0050473	biolink:NamedThing	arachidonate 15-lipoxygenase activity	Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.	got7fsn_ti	arachidonate omega(6) lipoxygenase activity|linoleic acid omega6-lipoxygenase activity|arachidonate:oxygen 15-oxidoreductase activity|omega6 lipoxygenase activity|15-lipoxygenase activity|arachidonate omega6 lipoxygenase activity											Reactome:R-HSA-9028255|EC:1.13.11.33|Reactome:R-HSA-9027607|Reactome:R-HSA-9018907|MetaCyc:ARACHIDONATE-15-LIPOXYGENASE-RXN|Reactome:R-HSA-9024881|Reactome:R-HSA-9020610|Reactome:R-HSA-9020262|Reactome:R-HSA-9025152|Reactome:R-HSA-9027532|Reactome:R-HSA-9027627|RHEA:16869|Reactome:R-HSA-9020275|Reactome:R-HSA-9026003|Reactome:R-HSA-9024872|Reactome:R-HSA-9020261|Reactome:R-HSA-2161951|Reactome:R-HSA-2162002		molecular_function											owl:Class	
GO:0030769	biolink:NamedThing	macrocin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin.	got7fsn_ti	macrocin methyltransferase activity|S-adenosyl-L-methionine-macrocin O-methyltransferase activity|S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase activity											KEGG_REACTION:R02858|RHEA:17269|EC:2.1.1.101|MetaCyc:MACROCIN-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0106360	biolink:NamedThing	2-hydroxy-3-methylhexadecanoyl-CoA lyase activity	Catalysis of the reaction: 2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.	got7fsn_ti							hjd	2021-02-03T16:14:49Z				RHEA:25379		molecular_function											owl:Class	
GO:0050171	biolink:NamedThing	phenol beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside.	got7fsn_ti	UDP glucosyltransferase activity|phenol-beta-D-glucosyltransferase activity|uridine diphosphoglucosyltransferase activity|phenol b-glucosyltransferase activity|UDPglucose:phenol beta-D-glucosyltransferase activity|UDP-glucose glucosyltransferase activity|UDPglucosyltransferase activity|UDP-glucose:phenol beta-D-glucosyltransferase activity											EC:2.4.1.35|MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0010737	biolink:NamedThing	protein kinase A signaling	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	PKA signaling cascade|protein kinase A signalling cascade|protein kinase A signal transduction|protein kinase A signaling cascade													biological_process											owl:Class	
GO:0021958	biolink:NamedThing	gracilis tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb.	got7fsn_ti	tract of Goll morphogenesis													biological_process											owl:Class	
GO:0036160	biolink:NamedThing	melanocyte-stimulating hormone secretion	The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.	got7fsn_ti	MSH secretion						bf	2012-03-26T01:16:55Z						biological_process											owl:Class	
GO:0120220	biolink:NamedThing	basal body patch	The region in the apical portion of multiciliated epithelial cells where the ciliary basal bodies cluster.	got7fsn_ti	centriolar patch						krc	2019-11-15T17:19:24Z						cellular_component											owl:Class	
GO:0045434	biolink:NamedThing	negative regulation of female receptivity, post-mating	Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating.	got7fsn_ti	downregulation of female receptivity, post-mating|down regulation of female receptivity, post-mating|down-regulation of female receptivity, post-mating|inhibition of female receptivity, post-mating													biological_process											owl:Class	
GO:0009514	biolink:NamedThing	glyoxysome	A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds.	got7fsn_ti												Wikipedia:Glyoxysome		cellular_component											owl:Class	
GO:0050238	biolink:NamedThing	pyridoxine 5-dehydrogenase activity	Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor.	got7fsn_ti	pyridoxal-5-dehydrogenase activity|pyridoxine:acceptor 5-oxidoreductase activity|pyridoxin 5-dehydrogenase activity|pyridoxol 5-dehydrogenase activity|pyridoxine 5'-dehydrogenase activity|pyridoxine:(acceptor) 5-oxidoreductase activity											EC:1.1.99.9|RHEA:14497|MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0017065	biolink:NamedThing	single-strand selective uracil DNA N-glycosylase activity	Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.	got7fsn_ti	single-strand selective monofunctional uracil-DNA glycosylase activity											Reactome:R-HSA-110221		molecular_function											owl:Class	
GO:0042116	biolink:NamedThing	macrophage activation	A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti	macrophage polarization													biological_process											owl:Class	
GO:0002936	biolink:NamedThing	bradykinin biosynthetic process	The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin.	got7fsn_ti							hjd	2012-10-17T14:24:24Z						biological_process											owl:Class	
GO:0000389	biolink:NamedThing	mRNA 3'-splice site recognition	Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.	got7fsn_ti	U12-type nuclear mRNA 3'-splice site recognition|nuclear mRNA 3'-splice site recognition|U2-type nuclear mRNA 3'-splice site recognition										GO:0000382|GO:0000383			biological_process											owl:Class	
GO:0005599	biolink:NamedThing	collagen type X trimer	A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets).	got7fsn_ti					Collagen X trimers have been observed to form hexagonal lattices in vitro, but in vivo they have been found in a fibril associated form (PMID:19693541).									cellular_component											owl:Class	
GO:0102126	biolink:NamedThing	coniferyl aldehyde 5-hydroxylase activity	Catalysis of the reaction: H+ + coniferyl aldehyde + NADPH + O2 <=> 5-hydroxy-coniferaldehyde + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-1142		molecular_function											owl:Class	
GO:0036141	biolink:NamedThing	L-phenylalanine-oxaloacetate transaminase activity	Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate.	got7fsn_ti	L-phenylalanine:oxaloacetate transaminase activity						bf	2012-03-08T10:35:44Z						molecular_function											owl:Class	
GO:0071056	biolink:NamedThing	alpha9-beta1 integrin-ADAM15 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.	got7fsn_ti	ITGA9-ITGB1-ADAM15 complex						mah	2009-11-03T03:59:49Z						cellular_component											owl:Class	
GO:0018785	biolink:NamedThing	haloacetate dehalogenase activity	Catalysis of the reaction: haloacetate + H2O = glycolate + halide.	got7fsn_ti	haloacetate halidohydrolase activity|monohaloacetate dehalogenase activity											UM-BBD_enzymeID:e0006|EC:3.8.1.3|MetaCyc:HALOACETATE-DEHALOGENASE-RXN|RHEA:11044		molecular_function											owl:Class	
GO:0102737	biolink:NamedThing	p-coumaroyltriacetic acid synthase activity	Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + H2O + 3 malonyl-CoA <=> 4 coenzyme A + 3 carbon dioxide + p-coumaroyltriacetate.	got7fsn_ti												MetaCyc:RXN-7577		molecular_function											owl:Class	
GO:0071613	biolink:NamedThing	granzyme B production	The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		mah	2010-02-05T04:47:15Z						biological_process											owl:Class	
GO:0003017	biolink:NamedThing	lymph circulation	The flow of lymph through the body of an animal.	got7fsn_ti														biological_process											owl:Class	
GO:0009290	biolink:NamedThing	DNA import into cell involved in transformation	The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell.	got7fsn_ti	DNA transport into cell during transformation|cellular DNA uptake|DNA import into cell involved in transformation|DNA import into cell|cellular DNA import during transformation													biological_process											owl:Class	
GO:0033450	biolink:NamedThing	GUC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GUC codon.	got7fsn_ti	valine tRNA|GTC codon-amino acid adaptor activity				Note that in the standard genetic code, GTC codes for valine.									molecular_function											owl:Class	
GO:0102593	biolink:NamedThing	UDP-glucose: N-methylanthranilate glucosyltransferase activity	Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP.	got7fsn_ti												MetaCyc:RXN-15371		molecular_function											owl:Class	
GO:0036057	biolink:NamedThing	slit diaphragm	A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.	got7fsn_ti							bf	2011-12-12T04:36:42Z						cellular_component											owl:Class	
GO:0102343	biolink:NamedThing	3-hydroxy-arachidoyl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA <=> trans-2-icosenoyl-CoA + H2O.	got7fsn_ti												EC:4.2.1.134|MetaCyc:RXN-13302		molecular_function											owl:Class	
GO:0050383	biolink:NamedThing	uracil dehydrogenase activity	Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor.	got7fsn_ti												RHEA:22752|MetaCyc:URACIL-DEHYDROGENASE-RXN|EC:1.17.99.4		molecular_function											owl:Class	
GO:0103033	biolink:NamedThing	beta-galactosidase activity (lactose isomerization)	Catalysis of the reaction: alpha-lactose = beta-(1->6)-galactobiose.	got7fsn_ti												MetaCyc:RXN0-5363		molecular_function											owl:Class	
GO:0031526	biolink:NamedThing	brush border membrane	The portion of the plasma membrane surrounding the brush border.	got7fsn_ti														cellular_component											owl:Class	
GO:0047395	biolink:NamedThing	glycerophosphoinositol glycerophosphodiesterase activity	Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+).	got7fsn_ti	1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity|sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity|sn-glycero(3)phosphoinositol glycerophosphohydrolase activity											MetaCyc:3.1.4.44-RXN|KEGG_REACTION:R01193|RHEA:16501|EC:3.1.4.44|Reactome:R-HSA-6813740		molecular_function											owl:Class	
GO:0018687	biolink:NamedThing	biphenyl 2,3-dioxygenase activity	Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.	got7fsn_ti	biphenyl dioxygenase activity|biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating)											RHEA:18165|UM-BBD_enzymeID:e0089|MetaCyc:1.14.12.18-RXN|EC:1.14.12.18		molecular_function											owl:Class	
GO:0050031	biolink:NamedThing	L-pipecolate oxidase activity	Catalysis of the reaction: L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2) + H(+). Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.	got7fsn_ti	L-pipecolic acid oxidase activity|L-pipecolate:oxygen 1,6-oxidoreductase activity											EC:1.5.3.7|MetaCyc:L-PIPECOLATE-OXIDASE-RXN|RHEA:11992|Reactome:R-HSA-6783880|KEGG_REACTION:R02204		molecular_function											owl:Class	
GO:0001665	biolink:NamedThing	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein.	got7fsn_ti	CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase activity|GalNAc alpha-2,6-sialyltransferase I activity											RHEA:11136|EC:2.4.99.3|MetaCyc:2.4.99.3-RXN|Reactome:R-HSA-9603991|Reactome:R-HSA-4084980		molecular_function											owl:Class	
GO:0050942	biolink:NamedThing	positive regulation of pigment cell differentiation	Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.	got7fsn_ti	up regulation of pigment cell differentiation|stimulation of pigment cell differentiation|up-regulation of pigment cell differentiation|activation of pigment cell differentiation|upregulation of pigment cell differentiation													biological_process											owl:Class	
GO:0048087	biolink:NamedThing	positive regulation of developmental pigmentation	Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.	got7fsn_ti	stimulation of developmental pigmentation|upregulation of developmental pigmentation|activation of developmental pigmentation|up regulation of developmental pigmentation|up-regulation of developmental pigmentation													biological_process											owl:Class	
GO:0045114	biolink:NamedThing	beta 2 integrin biosynthetic process	The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit.	got7fsn_ti	beta 2 integrin synthesis|beta 2 integrin formation|beta 2 integrin anabolism|beta 2 integrin biosynthesis													biological_process											owl:Class	
GO:0052862	biolink:NamedThing	glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group	Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.	got7fsn_ti	laminarinase activity|laminaranase activity|1,3-(1,4)-beta-D-glucan 4-glucanohydrolase activity						ai	2011-12-06T05:27:26Z				EC:3.2.1.6|MetaCyc:3.2.1.6-RXN		molecular_function											owl:Class	
GO:0019179	biolink:NamedThing	dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity	Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate.	got7fsn_ti	thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase activity|thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase activity|thymidine diphospho-4-amino-6-deoxyglucose aminotransferase activity|dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase activity|dTDP-4-amino-4,6-dideoxy-D-glucose aminotransferase activity|TDP-4-oxo-6-deoxy-D-glucose transaminase activity|thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase activity|TDP-4-keto-6-deoxy-D-glucose transaminase activity											MetaCyc:2.6.1.33-RXN|RHEA:19085|EC:2.6.1.33		molecular_function											owl:Class	
GO:0070204	biolink:NamedThing	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity	Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2).	got7fsn_ti	MenD|SEPHCHC synthase activity				Note that this function was formerly EC:4.1.3.18.							KEGG_REACTION:R08165|MetaCyc:2.5.1.64-RXN|RHEA:25593|EC:2.2.1.9		molecular_function											owl:Class	
GO:0019488	biolink:NamedThing	ribitol catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate.	got7fsn_ti	ribitol utilization|ribitol degradation to xylulose 5-phosphate|ribitol breakdown to xylulose 5-phosphate											MetaCyc:RIBITOLUTIL-PWY		biological_process											owl:Class	
GO:0050111	biolink:NamedThing	mycocerosate synthase activity	Catalysis of the reaction: acyl-CoA + 7n H(+) + n methylmalonyl-CoA + 2n NADPH = n CO(2) + n CoA + n H(2)O + multi-methyl-branched acyl-CoA + 2n NADP(+).	got7fsn_ti	acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)|mycocerosic acid synthase activity											EC:2.3.1.111|KEGG_REACTION:R05189|RHEA:10588|MetaCyc:MYCOCEROSATE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0016250	biolink:NamedThing	N-sulfoglucosamine sulfohydrolase activity	Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.	got7fsn_ti	N-sulphoglucosamine sulphohydrolase activity|2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)|sulphamidase activity|sulfoglucosamine sulfamidase activity|heparin sulfamidase activity|N-sulfo-D-glucosamine sulfohydrolase activity											Reactome:R-HSA-2090043|EC:3.10.1.1|Reactome:R-HSA-1678708|Reactome:R-HSA-9036050|Reactome:R-HSA-2263444|MetaCyc:N-SULFOGLUCOSAMINE-SULFOHYDROLASE-RXN|RHEA:17881		molecular_function											owl:Class	
GO:0047621	biolink:NamedThing	acylpyruvate hydrolase activity	Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate.	got7fsn_ti	3-acylpyruvate acylhydrolase activity											MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN|RHEA:19009|UM-BBD_reactionID:r1401|EC:3.7.1.5		molecular_function											owl:Class	
GO:0009239	biolink:NamedThing	enterobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.	got7fsn_ti	enterobactin biosynthetic process, peptide modification|enterobactin biosynthetic process, peptide formation|enterobactin synthetase|enterobactin anabolism|enterochelin biosynthesis|enterobactin biosynthesis|enterochelin biosynthetic process|enterobactin formation|enterobactin synthesis										GO:0031191|GO:0031192	MetaCyc:ENTBACSYN-PWY		biological_process											owl:Class	
GO:0071443	biolink:NamedThing	tDNA binding	Binding to DNA sequences encoding transfer RNA.	got7fsn_ti							mah	2009-12-16T03:47:31Z						molecular_function											owl:Class	
GO:0010855	biolink:NamedThing	adenylate cyclase inhibitor activity	Decreases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0018740	biolink:NamedThing	2'-hydroxybiphenyl-2-sulfinate desulfinase activity	Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H(2)O = biphenyl-2-ol + sulfite.	got7fsn_ti	HBPSi desulfinase activity|2'-hydroxybiphenyl-2-sulfinate sulfohydrolase activity|2'-hydroxybiphenyl-2-sulfinate sulfinolyase activity|2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase activity|HPBS desulfinase activity|2-(2-hydroxyphenyl)benzenesulfinate hydrolase activity|gene dszB-encoded hydrolase activity|2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase activity|DszB|2-(2-hydroxyphenyl)benzenesulphinate hydrolase activity|2-(2-hydroxyphenyl)benzenesulfinate desulfinase activity|2-(2'-hydroxyphenyl)benzenesulfinate desulfinase activity|dibenzothiophene desulfurization enzyme B											UM-BBD_enzymeID:e0216|RHEA:12945|EC:3.13.1.3|MetaCyc:RXN-624|KEGG_REACTION:R07311		molecular_function											owl:Class	
GO:1990081	biolink:NamedThing	trimethylamine receptor activity	Combining with the biogenic amine trimethylamine to initiate a change in cell activity.	got7fsn_ti							sp	2013-04-30T10:57:07Z						molecular_function											owl:Class	
GO:0061792	biolink:NamedThing	secretory granule maturation	Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling.	got7fsn_ti							dph	2016-09-09T13:24:34Z						biological_process											owl:Class	
GO:0002289	biolink:NamedThing	NK T cell proliferation involved in immune response	The expansion of a NK T cell population by cell division as part of an immune response.	got7fsn_ti	NK T cell proliferation during immune response|natural killer T lymphocyte proliferation during immune response|NK T-cell proliferation during immune response|natural killer T-lymphocyte proliferation during immune response|natural killer T-cell proliferation during immune response|NK T-lymphocyte proliferation during immune response|NK T lymphocyte proliferation during immune response													biological_process											owl:Class	
GO:0002288	biolink:NamedThing	NK T cell activation involved in immune response	The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	natural killer T-lymphocyte activation during immune response|natural killer T-cell activation during immune response|NK T-lymphocyte activation during immune response|NK T-cell activation during immune response|natural killer T lymphocyte activation during immune response|NK T lymphocyte activation during immune response|NK T cell activation during immune response													biological_process											owl:Class	
GO:0102300	biolink:NamedThing	linoleate 9R-lipoxygenase activity	Catalysis of the reaction: linoleate + O2 = 9(R)-HPODE.	got7fsn_ti												RHEA:31691|MetaCyc:RXN-12760|EC:1.13.11.61		molecular_function											owl:Class	
GO:0004411	biolink:NamedThing	homogentisate 1,2-dioxygenase activity	Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+).	got7fsn_ti	homogentisic acid oxidase activity|homogentisate dioxygenase activity|homogentisic oxygenase activity|homogentisate:oxygen 1,2-oxidoreductase (decyclizing)|homogentisate oxidase activity|homogentisate oxygenase activity|homogentisic acid oxygenase activity|homogentisicase activity											RHEA:15449|UM-BBD_reactionID:r0105|MetaCyc:HOMOGENTISATE-12-DIOXYGENASE-RXN|Reactome:R-HSA-71164|EC:1.13.11.5|KEGG_REACTION:R02519		molecular_function											owl:Class	
GO:0047963	biolink:NamedThing	glycine N-choloyltransferase activity	Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate.	got7fsn_ti	cholyl-CoA:taurine N-acyltransferase activity|bile acid-CoA:amino acid N-acyltransferase activity|choloyl-CoA:glycine N-choloyltransferase activity|BACAT activity|glycine--taurine N-acyltransferase activity|cholyl-CoA glycine-taurine N-acyltransferase activity|amino acid N-choloyltransferase activity|BAT activity											RHEA:14001|MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN|EC:2.3.1.65		molecular_function											owl:Class	
GO:0016045	biolink:NamedThing	detection of bacterium	The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.	got7fsn_ti	perception of bacterium|detection of bacteria|perception of bacteria										GO:0009598|GO:0009681			biological_process											owl:Class	
GO:0030978	biolink:NamedThing	alpha-glucan metabolic process	The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.	got7fsn_ti	alpha-glucan metabolism													biological_process											owl:Class	
GO:0001591	biolink:NamedThing	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity.	got7fsn_ti	dopamine D3 receptor activity|dopamine D4 receptor activity|dopamine D2 receptor activity										GO:0001592|GO:0001670|GO:0001593			molecular_function											owl:Class	
GO:0018751	biolink:NamedThing	3,5-dichlorophenylcarboximide hydrolase activity	Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate.	got7fsn_ti												UM-BBD_reactionID:r0707		molecular_function											owl:Class	
GO:0050750	biolink:NamedThing	low-density lipoprotein particle receptor binding	Binding to a low-density lipoprotein receptor.	got7fsn_ti	low-density lipoprotein receptor binding|LDL receptor binding													molecular_function											owl:Class	
GO:0102346	biolink:NamedThing	3-hydroxy-cerotoyl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA(4-) <=> trans-2-hexacosenoyl-CoA(4-) + H2O.	got7fsn_ti												MetaCyc:RXN-13305		molecular_function											owl:Class	
GO:0120235	biolink:NamedThing	regulation of posttranslational protein targeting to membrane, translocation	Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane.	got7fsn_ti	regulation of N-terminal signal peptide-independent translocation into the ER|regulation of posttranslational endoplasmic reticulum membrane protein translocation|regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation	https://github.com/geneontology/go-ontology/issues/19791					krc	2020-08-03T16:46:15Z						biological_process											owl:Class	
GO:0046571	biolink:NamedThing	aspartate-2-keto-4-methylthiobutyrate transaminase activity	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate.	got7fsn_ti														molecular_function											owl:Class	
GO:0019480	biolink:NamedThing	L-alanine oxidation to pyruvate via D-alanine	The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate.	got7fsn_ti												MetaCyc:ALADEG-PWY		biological_process											owl:Class	
GO:0034781	biolink:NamedThing	N-cyclohexylformamide amidohydrolase activity	Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate.	got7fsn_ti												UM-BBD_reactionID:r1030		molecular_function											owl:Class	
GO:0019682	biolink:NamedThing	glyceraldehyde-3-phosphate metabolic process	The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.	got7fsn_ti	glyceraldehyde-3-phosphate metabolism|glyceraldehyde 3-phosphate metabolic process|glyceraldehyde 3-phosphate metabolism													biological_process											owl:Class	
GO:1990506	biolink:NamedThing	mitotic DNA-dependent DNA replication	A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle.	got7fsn_ti							al	2014-10-01T14:13:23Z						biological_process											owl:Class	
GO:0072348	biolink:NamedThing	sulfur compound transport	The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	sulfur-containing compound transport						mah	2010-11-11T11:43:56Z						biological_process											owl:Class	
GO:0062245	biolink:NamedThing	double membrane vesicle viral factory inner membrane	The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.	got7fsn_ti	inner membrane of double membrane vesicle viral factory						dph	2020-04-20T20:55:49Z						cellular_component											owl:Class	
GO:0140509	biolink:NamedThing	epithelium-like organization	The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins.	got7fsn_ti							pg	2020-08-28T07:29:53Z						biological_process											owl:Class	
GO:0009944	biolink:NamedThing	polarity specification of adaxial/abaxial axis	The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.	got7fsn_ti														biological_process											owl:Class	
GO:0008609	biolink:NamedThing	alkylglycerone-phosphate synthase activity	Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.	got7fsn_ti	alkyldihydroxyacetone phosphate synthetase activity|alkyl-DHAP|DHAP-AT|alkyl-DHAP synthase activity|dihydroxyacetone-phosphate acyltransferase activity|alkyldihydroxyacetonephosphate synthase activity|1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase activity|alkyl DHAP synthetase activity											EC:2.5.1.26|Reactome:R-HSA-390427|RHEA:36171|MetaCyc:ALKYLGLYCERONE-PHOSPHATE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0046933	biolink:NamedThing	proton-transporting ATP synthase activity, rotational mechanism	Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).	got7fsn_ti	hydrogen ion transporting ATP synthase activity, rotational mechanism|H+-transporting ATP synthase activity|hydrogen ion translocating F-type ATPase activity|hydrogen ion transporting two-sector ATPase activity	https://github.com/geneontology/go-ontology/issues/19380										Reactome:R-HSA-164832|EC:7.1.2.2|MetaCyc:ATPSYN-RXN|TC:3.A.2.1.1|RHEA:57720		molecular_function											owl:Class	
GO:1990776	biolink:NamedThing	response to angiotensin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.	got7fsn_ti							sl	2015-06-16T17:41:17Z						biological_process											owl:Class	
GO:0043698	biolink:NamedThing	iridosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance.	got7fsn_ti	reflecting platelet													cellular_component											owl:Class	
GO:0036182	biolink:NamedThing	asperthecin metabolic process	The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.	got7fsn_ti	asperthecin metabolism						bf	2012-04-16T11:35:24Z						biological_process											owl:Class	
GO:0102479	biolink:NamedThing	quercetin 3-O-beta:-D-galactosyltransferase activity	Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose <=> quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+.	got7fsn_ti												EC:2.4.1.234|MetaCyc:RXN-14109		molecular_function											owl:Class	
GO:0034973	biolink:NamedThing	Sid2-Mob1 complex	A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex.	got7fsn_ti	Sid2p-Mob1p complex|Dbf2p-Mob1p complex|Sid2-Mob1 kinase complex													cellular_component											owl:Class	
GO:0047095	biolink:NamedThing	2-hydroxycyclohexanone 2-monooxygenase activity	Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-oxohexanoate + H(2)O + NADP(+).	got7fsn_ti	2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing)											EC:1.14.13.66|KEGG_REACTION:R03281|RHEA:33283|MetaCyc:1.14.13.66-RXN		molecular_function											owl:Class	
GO:0055052	biolink:NamedThing	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.	got7fsn_ti														cellular_component											owl:Class	
GO:0047851	biolink:NamedThing	dicarboxylate-CoA ligase activity	Catalysis of the reaction: ATP + an omega-dicarboxylic acid + CoASH= AMP + diphosphate + an omega-carboxyacyl-CoA.	got7fsn_ti	omega-dicarboxylate:CoA ligase (AMP-forming)|carboxylyl-CoA synthetase activity											RHEA:14289|EC:6.2.1.23|MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN		molecular_function											owl:Class	
GO:0036245	biolink:NamedThing	cellular response to menadione	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position.	got7fsn_ti	cellular response to vitamin K3						bf	2012-05-28T10:23:02Z						biological_process											owl:Class	
GO:0001001	biolink:NamedThing	mitochondrial single-subunit type RNA polymerase binding	Binding to a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.	got7fsn_ti							krc	2010-08-17T05:01:28Z						molecular_function											owl:Class	
GO:0038161	biolink:NamedThing	prolactin signaling pathway	A series of molecular signals initiated by the binding of the peptide hormone prolactin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	prolactin-mediated signaling pathway|PRL signaling pathway						bf	2012-05-14T01:52:59Z						biological_process											owl:Class	
GO:0090375	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter in response to iron deficiency						tb	2010-09-01T01:22:23Z						biological_process											owl:Class	
GO:1990632	biolink:NamedThing	branching involved in submandibular gland morphogenesis	The process in which the branching structure of the submandibular gland is generated and organized.	got7fsn_ti	submandibular gland ductal branching|submandibular gland branching morphogenesis						cls	2015-02-10T14:40:01Z						biological_process											owl:Class	
GO:0060445	biolink:NamedThing	branching involved in salivary gland morphogenesis	The process in which the branching structure of the salivary gland is generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0090519	biolink:NamedThing	anoxia protection	Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia.	got7fsn_ti							tb	2012-12-21T15:37:37Z						biological_process											owl:Class	
GO:0045850	biolink:NamedThing	positive regulation of nurse cell apoptotic process	Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process.	got7fsn_ti	upregulation of nurse cell apoptosis|up-regulation of nurse cell apoptosis|stimulation of nurse cell apoptosis|up regulation of nurse cell apoptosis|activation of nurse cell apoptosis|positive regulation of nurse cell apoptosis													biological_process											owl:Class	
GO:0018795	biolink:NamedThing	2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity	Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate.	got7fsn_ti												UM-BBD_reactionID:r0621		molecular_function											owl:Class	
GO:0019180	biolink:NamedThing	dTDP-4-amino-4,6-dideoxygalactose transaminase activity	Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose.	got7fsn_ti	thymidine diphosphoaminodideoxygalactose aminotransferase activity|dTDP-fucosamine aminotransferase activity|thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase activity|dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase activity|dTDP-4-amino-4,6-dideoxygalactose aminotransferase activity											MetaCyc:2.6.1.59-RXN|KEGG_REACTION:R04438|RHEA:10368|EC:2.6.1.59		molecular_function											owl:Class	
GO:0102536	biolink:NamedThing	sakuranetin 6-hydroxylase activity	Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-14754		molecular_function											owl:Class	
GO:0102680	biolink:NamedThing	campest-4-en-3-one hydroxylase activity	Catalysis of the reaction: H+ + campest-4-en-3-one + O2 + NADPH <=> (22S)-22-hydroxycampest-4-en-3-one + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-4231		molecular_function											owl:Class	
GO:0047603	biolink:NamedThing	acetoacetyl-CoA hydrolase activity	Catalysis of the reaction: acetoacetyl-CoA + H(2)O = acetoacetate + CoA + H(+).	got7fsn_ti	acetoacetyl CoA deacylase activity|acetoacetyl coenzyme A deacylase activity|acetoacetyl coenzyme A hydrolase activity											EC:3.1.2.11|RHEA:15673|KEGG_REACTION:R01358|MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN		molecular_function											owl:Class	
GO:0008851	biolink:NamedThing	ethanolamine ammonia-lyase activity	Catalysis of the reaction: ethanolamine = acetaldehyde + NH3.	got7fsn_ti	ethanolamine deaminase activity|ethanolamine ammonia-lyase (acetaldehyde-forming) activity											RHEA:15313|MetaCyc:ETHAMLY-RXN|EC:4.3.1.7		molecular_function											owl:Class	
GO:0051072	biolink:NamedThing	4,6-pyruvylated galactose residue biosynthetic process	The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.	got7fsn_ti	4,6-pyruvylated galactose residue formation|4,6-pyruvylated galactose residue biosynthesis|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthesis|PvGal biosynthetic process|PvGal biosynthesis|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthetic process|4,6-pyruvylated galactose residue synthesis|4,6-pyruvylated galactose residue anabolism													biological_process											owl:Class	
GO:0102466	biolink:NamedThing	beta-carotene 2,2'-beta-hydroxylase activity	Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O.	got7fsn_ti												MetaCyc:RXN-14019		molecular_function											owl:Class	
GO:0035403	biolink:NamedThing	histone kinase activity (H3-T6 specific)	Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3.	got7fsn_ti	histone threonine kinase activity (H3-T6 specific)|histone-threonine kinase activity (H3-T6 specific)						bf	2010-03-24T10:05:39Z						molecular_function											owl:Class	
GO:0071574	biolink:NamedThing	protein localization to medial cortex	A process in which a protein is transported to, or maintained in, the medial cortex.	got7fsn_ti	protein localisation to medial cortex						mah	2010-01-26T05:17:50Z						biological_process											owl:Class	
GO:0047624	biolink:NamedThing	adenosine-tetraphosphatase activity	Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate.	got7fsn_ti	adenosine-tetraphosphate phosphohydrolase activity											EC:3.6.1.14|MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN|RHEA:24500		molecular_function											owl:Class	
GO:0070082	biolink:NamedThing	clathrin-sculpted monoamine transport vesicle lumen	The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle.	got7fsn_ti	clathrin sculpted monoamine transport vesicle lumen|clathrin sculpted monoamine constitutive secretory pathway transport vesicle lumen													cellular_component											owl:Class	
GO:0042334	biolink:NamedThing	taxis to electron acceptor	The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate.	got7fsn_ti	taxis in response to electron acceptor													biological_process											owl:Class	
GO:0036151	biolink:NamedThing	phosphatidylcholine acyl-chain remodeling	Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.	got7fsn_ti							bf	2012-03-14T01:54:13Z						biological_process											owl:Class	
GO:0042540	biolink:NamedThing	hemoglobin catabolic process	The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids.	got7fsn_ti	hemoglobin hydrolysis|hemoglobin degradation|haemoglobin catabolic process|hemoglobin breakdown|hemoglobin catabolism|haemoglobin catabolism|haemoglobin hydrolysis				Note that 'hydrolysis' is actually a reaction rather than a process. The synonym 'hemoglobin hydrolysis' was the text string associated with the secondary ID GO:0020029, which was retained because its definition did describe a process.						GO:0020029			biological_process											owl:Class	
GO:0043877	biolink:NamedThing	galactosamine-6-phosphate isomerase activity	Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3.	got7fsn_ti	AgaI|galactosamine-6-phosphate deaminase activity				This function is part of the pathway of N-acetyl-galactosamine and galactosamine utilization.									molecular_function											owl:Class	
GO:0097183	biolink:NamedThing	protein C inhibitor-coagulation factor XI complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI.	got7fsn_ti	protein C inhibitor-F11 complex|SERPINA5-coagulation factor XI complex|plasma serine protease inhibitor-coagulation factor XI complex|serpin A5-coagulation factor XI complex|PCI-coagulation factor XI complex						pr	2011-10-16T09:03:22Z						cellular_component											owl:Class	
GO:0097415	biolink:NamedThing	cortical Lewy body	Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils.	got7fsn_ti							pr	2012-11-06T16:29:11Z				NIF_Subcellular:sao4040591221		cellular_component											owl:Class	
GO:0007172	biolink:NamedThing	signal complex assembly	The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell.	got7fsn_ti	signal complex formation													biological_process											owl:Class	
GO:0102312	biolink:NamedThing	4-coumaroyl 2'-hydroxylase activity	Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-12963|EC:1.14.11.62|RHEA:57868		molecular_function											owl:Class	
GO:0034574	biolink:NamedThing	didemethylisoproturon dehydrogenase activity	Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0899|EC:1.17.99.-		molecular_function											owl:Class	
GO:0034066	biolink:NamedThing	Ric1-Rgp1 guanyl-nucleotide exchange factor complex	A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.	got7fsn_ti	Ric1p-Rgp1p complex													cellular_component											owl:Class	
GO:0006433	biolink:NamedThing	prolyl-tRNA aminoacylation	The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0120210	biolink:NamedThing	rod telodendria	Rod telodendria are projections that originate from the rod pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.	got7fsn_ti							krc	2019-05-21T00:34:22Z						cellular_component											owl:Class	
GO:0018833	biolink:NamedThing	DDT-dehydrochlorinase activity	Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+).	got7fsn_ti	DDT-as|DDTase activity|1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity|1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]|DDT dehydrochlorinase activity|DDT-ase activity											KEGG_REACTION:R04522|UM-BBD_reactionID:r0439|RHEA:19217|EC:4.5.1.1|MetaCyc:DDT-DEHYDROCHLORINASE-RXN		molecular_function											owl:Class	
GO:0051659	biolink:NamedThing	maintenance of mitochondrion location	Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of mitochondria localization|maintenance of mitochondrion localization													biological_process											owl:Class	
GO:0033476	biolink:NamedThing	indoleacetic acid ester conjugate biosynthetic process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond.	got7fsn_ti	indoleacetic acid ester conjugate synthesis|indoleacetic acid ester conjugate formation|indoleacetic acid ester conjugate biosynthesis|indoleacetic acid ester conjugate anabolism|indole acetic acid ester conjugate biosynthetic process|indole acetic acid ester conjugate biosynthesis|IAA ester conjugate biosynthetic process											MetaCyc:PWY-1741		biological_process											owl:Class	
GO:0009042	biolink:NamedThing	valine-pyruvate transaminase activity	Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.	got7fsn_ti	alanine--valine transaminase activity|valine-pyruvate aminotransferase activity|L-valine:pyruvate aminotransferase activity|transaminase C activity|alanine-oxoisovalerate aminotransferase activity|valine--pyruvate aminotransferase activity											MetaCyc:VALINE-PYRUVATE-AMINOTRANSFER-RXN|EC:2.6.1.66|RHEA:22912|KEGG_REACTION:R01215		molecular_function											owl:Class	
GO:0015182	biolink:NamedThing	L-asparagine transmembrane transporter activity	Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid.	got7fsn_ti	asparagine/glutamine permease activity|L-asparagine transporter activity													molecular_function											owl:Class	
GO:0051764	biolink:NamedThing	actin crosslink formation	The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.	got7fsn_ti	actin bundling|formation of actin crosslink|bridging actin filaments|actin crosslinking				See also the molecular function term 'protein binding, bridging ; GO:0030674'.									biological_process											owl:Class	
GO:0034972	biolink:NamedThing	histone H3-R26 methylation	The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone.	got7fsn_ti	histone lysine H3 R26 methylation|histone H3 R26 methylation|histone H3R26me													biological_process											owl:Class	
GO:0008061	biolink:NamedThing	chitin binding	Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.	got7fsn_ti														molecular_function											owl:Class	
GO:0016327	biolink:NamedThing	apicolateral plasma membrane	The apical end of the lateral plasma membrane of epithelial cells.	got7fsn_ti	apical lateral plasma membrane													cellular_component											owl:Class	
GO:0005609	biolink:NamedThing	laminin-4 complex	A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.	got7fsn_ti	laminin-221 complex													cellular_component											owl:Class	
GO:0052067	biolink:NamedThing	antiphagocytosis	Any process in which a symbiont avoids phagocytosis by a host cell, for example a phagocyte or a macrophage. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	downregulation by symbiont of entry into host cell via phagocytosis|negative regulation by organism of entry into cell of other organism via phagocytosis involved in symbiotic interaction|modulation by organism of entry into host via host phagocytosis|modulation by symbiont of entry into host via phagocytosis|negative regulation by organism of entry into host cell via host phagocytosis|down regulation by symbiont of entry into host cell via phagocytosis|negative regulation by symbiont of entry into host cell via phagocytosis|phagocytosis avoidence|inhibition by symbiont of entry into host cell via phagocytosis|down-regulation by symbiont of entry into host cell via phagocytosis	https://github.com/geneontology/go-ontology/issues/17983|https://github.com/geneontology/go-ontology/issues/18562									GO:0052483|GO:0052380			biological_process											owl:Class	
GO:0047209	biolink:NamedThing	coniferyl-alcohol glucosyltransferase activity	Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP.	got7fsn_ti	UDP-glucose coniferyl alcohol glucosyltransferase activity|UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity|UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity|uridine diphosphoglucose-coniferyl alcohol glucosyltransferase activity											MetaCyc:2.4.1.111-RXN|RHEA:23944|EC:2.4.1.111		molecular_function											owl:Class	
GO:0004846	biolink:NamedThing	urate oxidase activity	Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide.	got7fsn_ti	urate:oxygen oxidoreductase activity|uricase activity|uric acid oxidase activity|uricase II activity											MetaCyc:URATE-OXIDASE-RXN|RHEA:21368|EC:1.7.3.3|UM-BBD_reactionID:r1322		molecular_function											owl:Class	
GO:0034537	biolink:NamedThing	2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity	Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde.	got7fsn_ti												UM-BBD_reactionID:r0783		molecular_function											owl:Class	
GO:1990380	biolink:NamedThing	Lys48-specific deubiquitinase activity	Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein.	got7fsn_ti	K48-specific deubiquitinating activity|K48-specific deubiquitinase activity						bf	2014-05-15T14:31:07Z				Reactome:R-HSA-5690870		molecular_function											owl:Class	
GO:0050781	biolink:NamedThing	ortho-trichlorophenol reductive dehalogenase activity	Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl.	got7fsn_ti	2,4,6-TCP reductive dehalogenase activity|2,4,6-trichlorophenol reductive dehalogenase activity													molecular_function											owl:Class	
GO:0050981	biolink:NamedThing	detection of electrical stimulus	The series of events by which an electrical stimulus is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0102427	biolink:NamedThing	allocryptopine 6-hydroxylase activity	Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ <=> 6-hydroxy-allocryptopine + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-13828		molecular_function											owl:Class	
GO:0018191	biolink:NamedThing	peptidyl-serine octanoylation	The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin.	got7fsn_ti												RESID:AA0290		biological_process											owl:Class	
GO:0060072	biolink:NamedThing	large conductance calcium-activated potassium channel activity	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	got7fsn_ti	large conductance KCa channel activity|BK channel activity|BK calcium-activated potassium channel activity|BK KCa channel activity										GO:0022895			molecular_function											owl:Class	
GO:0043981	biolink:NamedThing	histone H4-K5 acetylation	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.	got7fsn_ti	histone H4 acetylation at K5													biological_process											owl:Class	
GO:0047180	biolink:NamedThing	salutaridinol 7-O-acetyltransferase activity	Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA.	got7fsn_ti	acetyl-CoA:salutaridinol 7-O-acetyltransferase activity											RHEA:22856|MetaCyc:2.3.1.150-RXN|KEGG_REACTION:R04723|EC:2.3.1.150		molecular_function											owl:Class	
GO:0016272	biolink:NamedThing	prefoldin complex	A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.	got7fsn_ti	GIM complex											Wikipedia:Prefoldin		cellular_component											owl:Class	
GO:0062210	biolink:NamedThing	shoot regeneration	The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot.	got7fsn_ti	shoot system regeneration						dph	2020-02-21T12:38:43Z						biological_process											owl:Class	
GO:0034670	biolink:NamedThing	chemotaxis to arachidonic acid	The directed movement of a motile cell or organism in response to the presence of arachidonic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0140684	biolink:NamedThing	histone H3-tri/dimethyl-lysine-9 demethylase activity	Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone H3K9me2 demethylase activity|histone H3K9me3 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089					pg	2021-07-09T06:03:55Z				RHEA:60200|EC:1.14.11.66		molecular_function											owl:Class	
GO:0004035	biolink:NamedThing	alkaline phosphatase activity	Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.	got7fsn_ti	orthophosphoric-monoester phosphohydrolase (alkaline optimum)|phosphomonoesterase activity|alkaline phenyl phosphatase activity|phosphate-monoester phosphohydrolase (alkaline optimum)|alkaline phosphomonoesterase activity|glycerophosphatase activity|alkaline phosphohydrolase activity											EC:3.1.3.1|MetaCyc:ALKAPHOSPHA-RXN|Reactome:R-HSA-8878787		molecular_function											owl:Class	
GO:0050888	biolink:NamedThing	determination of stimulus location	The determination of where on the body surface, within the body or in the environment a stimulus originates.	got7fsn_ti														biological_process											owl:Class	
GO:0072591	biolink:NamedThing	citrate-L-glutamate ligase activity	Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.	got7fsn_ti							mah	2011-02-10T03:24:26Z						molecular_function											owl:Class	
GO:0032607	biolink:NamedThing	interferon-alpha production	The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interferon-alpha secretion|interferon-alpha biosynthetic process|IFNA production|IFN-alpha production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072642|GO:0045349			biological_process											owl:Class	
GO:0140548	biolink:NamedThing	envenomation resulting in blood agglutination in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism.	got7fsn_ti	envenomation resulting in erythrocytes agglutination in other organism|envenomation resulting in red blood cells agglutination in other organism	https://github.com/geneontology/go-ontology/issues/18979					pg	2020-11-11T21:42:31Z						biological_process											owl:Class	
GO:0030976	biolink:NamedThing	thiamine pyrophosphate binding	Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.	got7fsn_ti	thiamin pyrophosphate binding|diphosphothiamin binding|aneurine pyrophosphate binding|TPP binding|cocarboxylase binding													molecular_function											owl:Class	
GO:0016785	biolink:NamedThing	selenotransferase activity	Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring selenium-containing groups	https://github.com/geneontology/go-ontology/issues/20486									GO:0016786	EC:2.9.1.-		molecular_function											owl:Class	
GO:0039512	biolink:NamedThing	suppression by virus of host protein tyrosine kinase activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein tyrosine kinase activity.	got7fsn_ti	downregulation by virus of host protein tyrosine kinase activity|down-regulation by virus of host protein tyrosine kinase activity|inhibition by virus of host protein tyrosine kinase activity|negative regulation by virus of host protein tyrosine kinase activity						bf	2011-06-16T02:27:26Z						biological_process											owl:Class	
GO:0032164	biolink:NamedThing	hyphal septin cap	A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.	got7fsn_ti														cellular_component											owl:Class	
GO:0044017	biolink:NamedThing	histone acetyltransferase activity (H3-K27 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27).	got7fsn_ti	histone lysine N-acetyltransferase activity (H3-K27 specific)													molecular_function											owl:Class	
GO:0019397	biolink:NamedThing	gallate catabolic process via 2-pyrone-4,6-dicarboxylate	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate.	got7fsn_ti	gallic acid catabolism via 2-pyrone-4,6-dicarboxylate|gallate breakdown via 2-pyrone-4,6-dicarboxylate|gallate degradation via 2-pyrone-4,6-dicarboxylate|gallic acid catabolic process via 2-pyrone-4,6-dicarboxylate											MetaCyc:GALLATE-DEGRADATION-I-PWY		biological_process											owl:Class	
GO:0018235	biolink:NamedThing	peptidyl-lysine carboxylation	The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine.	got7fsn_ti												RESID:AA0114		biological_process											owl:Class	
GO:0030266	biolink:NamedThing	quinate 3-dehydrogenase (NAD+) activity	Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.	got7fsn_ti	quinate:NAD 3-oxidoreductase activity|quinate:NAD(+) 3-oxidoreductase activity|quinate:NAD(+) 5-oxidoreductase activity|quinate:NAD 5-oxidoreductase activity|quinic dehydrogenase activity											KEGG_REACTION:R01872|EC:1.1.1.24|MetaCyc:QUINATE-5-DEHYDROGENASE-RXN|RHEA:22364|EC:1.1.1.282		molecular_function											owl:Class	
GO:0034158	biolink:NamedThing	toll-like receptor 8 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 8.	got7fsn_ti	TLR8 signaling pathway|toll-like receptor 8 signalling pathway													biological_process											owl:Class	
GO:0035584	biolink:NamedThing	calcium-mediated signaling using intracellular calcium source	A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.	got7fsn_ti	calcium-mediated signalling using intracellular calcium source|calcium signaling using intracellular calcium source|calcium signalling using intracellular calcium source						bf	2010-10-18T11:01:08Z						biological_process											owl:Class	
GO:0033560	biolink:NamedThing	folate reductase activity	Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+.	got7fsn_ti												Reactome:R-HSA-197963|RHEA:31103|Reactome:R-HSA-197972		molecular_function											owl:Class	
GO:0002534	biolink:NamedThing	cytokine production involved in inflammatory response	The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	cytokine production involved in acute inflammatory response													biological_process											owl:Class	
GO:0047663	biolink:NamedThing	aminoglycoside 6'-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H(+). This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring.	got7fsn_ti	AAC(6') activity|6'-aminoglycoside-N-acetyltransferase activity|aminoglycoside-6'-acetyltransferase activity|kanamycin 6'-N-acetyltransferase activity|acetyl-CoA:kanamycin-B N6'-acetyltransferase activity|aminoglycoside N6'-acetyltransferase activity|aminoglycoside-6-N-acetyltransferase activity											KEGG_REACTION:R01889|RHEA:16449|MetaCyc:AMINOGLYCOSIDE-N6-ACETYLTRANSFERASE-RXN|EC:2.3.1.82		molecular_function											owl:Class	
GO:0035616	biolink:NamedThing	histone H2B conserved C-terminal lysine deubiquitination	A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.	got7fsn_ti	fission yeast H2B K119 deubiquitination|mammalian H2B K120 deubiquitination|budding yeast H2B K123 deubiquitination						bf	2010-12-03T10:36:44Z						biological_process											owl:Class	
GO:0044546	biolink:NamedThing	NLRP3 inflammasome complex assembly	The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell.	got7fsn_ti	NLRP3 inflammasome activation|NALP3 inflammasome complex assembly	https://github.com/geneontology/go-ontology/issues/21092					jl	2012-03-22T01:27:21Z						biological_process											owl:Class	
GO:0030411	biolink:NamedThing	scytalone dehydratase activity	Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H(2)O.	got7fsn_ti	scytalone 7,8-hydro-lyase activity|scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming)											KEGG_REACTION:R02907|MetaCyc:SCYTALONE-DEHYDRATASE-RXN|EC:4.2.1.94|RHEA:24396		molecular_function											owl:Class	
GO:0044548	biolink:NamedThing	S100 protein binding	Binding to a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.	got7fsn_ti	S100 binding|S100 beta binding|S100 alpha binding						jl	2012-03-22T03:23:51Z			GO:0048155|GO:0048154			molecular_function											owl:Class	
GO:0072593	biolink:NamedThing	reactive oxygen species metabolic process	The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.	got7fsn_ti	reactive oxygen species metabolism|ROS metabolic process						mah	2011-02-11T10:50:06Z						biological_process											owl:Class	
GO:0050225	biolink:NamedThing	pseudouridine kinase activity	Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5'-phosphate.	got7fsn_ti	ATP:pseudouridine 5'-phosphotransferase activity|pseudouridine kinase (phosphorylating)											MetaCyc:PSEUDOURIDINE-KINASE-RXN|KEGG_REACTION:R03315|EC:2.7.1.83|RHEA:22448		molecular_function											owl:Class	
GO:1990471	biolink:NamedThing	piRNA uni-strand cluster binding	Binding to uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa.	got7fsn_ti							bhm	2014-08-29T14:37:35Z						molecular_function											owl:Class	
GO:0051767	biolink:NamedThing	nitric-oxide synthase biosynthetic process	The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.	got7fsn_ti	NOS biosynthesis|nitric-oxide synthase 2 biosynthetic process|NOS1 biosynthesis|NO synthase biosynthesis|NOS2 synthase biosynthesis|nitric-oxide synthase-3 biosynthetic process|NO synthase biosynthetic process|NOS2 biosynthesis|NOS3 biosynthesis|NOS2 synthase biosynthetic process|nitric-oxide synthase-2 biosynthetic process|NOS biosynthetic process|nitric-oxide synthase (type 2) biosynthesis|nitric-oxide synthase-1 biosynthetic process|endothelial nitric-oxide synthase biosynthetic process|nitric-oxide synthase (type II) biosynthetic process|nitric-oxide synthase (type 2) biosynthetic process|inducible nitric-oxide synthase biosynthetic process|nitric-oxide synthase (type II) biosynthesis|brain nitric-oxide synthase biosynthetic process										GO:0051768			biological_process											owl:Class	
GO:0050074	biolink:NamedThing	malate-CoA ligase activity	Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA.	got7fsn_ti	malate:CoA ligase (ADP-forming)|malyl-CoA synthetase activity|malyl coenzyme A synthetase activity|malate thiokinase activity											EC:6.2.1.9|MetaCyc:MALATE--COA-LIGASE-RXN|RHEA:26193		molecular_function											owl:Class	
GO:0010246	biolink:NamedThing	rhamnogalacturonan I biosynthetic process	The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide.	got7fsn_ti	rhamnogalacturonan I synthesis|rhamnogalacturonan I biosynthesis|rhamnogalacturonan I anabolism|rhamnogalacturonan I formation													biological_process											owl:Class	
GO:0001966	biolink:NamedThing	thigmotaxis	The directed movement of a motile cell or organism in response to touch.	got7fsn_ti	stereotaxis|taxis in response to touch stimulus|taxis in response to mechanical stimulus													biological_process											owl:Class	
GO:0102740	biolink:NamedThing	theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity	Catalysis of the reaction: theobromine + S-adenosyl-L-methionine  <=> H+ + caffeine + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-7599|EC:2.1.1.160|RHEA:20944		molecular_function											owl:Class	
GO:0031481	biolink:NamedThing	myosin XI complex	A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.	got7fsn_ti														cellular_component											owl:Class	
GO:0010384	biolink:NamedThing	cell wall proteoglycan metabolic process	The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.	got7fsn_ti	cell wall proteoglycan metabolism													biological_process											owl:Class	
GO:0099505	biolink:NamedThing	regulation of presynaptic membrane potential	Any process that modulates the potential difference across a presynaptic membrane.	got7fsn_ti	regulation of pre-synaptic membrane potential													biological_process											owl:Class	
GO:0048203	biolink:NamedThing	vesicle targeting, trans-Golgi to endosome	The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome.	got7fsn_ti	trans-Golgi to endosome targeting													biological_process											owl:Class	
GO:0031476	biolink:NamedThing	myosin VI complex	A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.	got7fsn_ti														cellular_component											owl:Class	
GO:0060112	biolink:NamedThing	generation of ovulation cycle rhythm	The process which controls the timing of the type of sexual cycle seen in female mammals.	got7fsn_ti	generation of menstrual cycle rhythm|generation of oestrus cycle rhythm|generation of estrus cycle rhythm													biological_process											owl:Class	
GO:0060982	biolink:NamedThing	coronary artery morphogenesis	The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.	got7fsn_ti							dph	2009-10-06T02:58:52Z						biological_process											owl:Class	
GO:0071057	biolink:NamedThing	alphav-beta3 integrin-ADAM15 complex	A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.	got7fsn_ti	ITGAV-ITGB3-ADAM15 complex						mah	2009-11-03T04:00:14Z						cellular_component											owl:Class	
GO:0010066	biolink:NamedThing	ground meristem histogenesis	The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.	got7fsn_ti														biological_process											owl:Class	
GO:0018551	biolink:NamedThing	hydrogensulfite reductase activity	Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor.	got7fsn_ti	dissimilatory-type sulfite reductase activity|dissimilatory sulfite reductase activity|hydrogensulphite reductase activity|bisulfite reductase activity|desulfoviridin activity|desulfofuscidin activity|trithionate:acceptor oxidoreductase activity|trithionate:(acceptor) oxidoreductase activity|desulforubidin activity											MetaCyc:HYDROGENSULFITE-REDUCTASE-RXN|RHEA:13209|UM-BBD_reactionID:r0627|EC:1.8.99.3		molecular_function											owl:Class	
GO:0050379	biolink:NamedThing	UDP-glucuronate 5'-epimerase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate.	got7fsn_ti	UDP-glucuronic acid epimerase activity|UDPglucuronate 5'-epimerase activity|UDP-glucuronate 5' epimerase activity|uridine diphosphoglucuronate 5'-epimerase activity|C-5-uronosyl epimerase activity|UDP-glucuronic acid 5'-epimerase activity											KEGG_REACTION:R01387|Reactome:R-HSA-2024100|Reactome:R-HSA-2076371|MetaCyc:UDP-GLUCURONATE-5-EPIMERASE-RXN		molecular_function											owl:Class	
GO:0070386	biolink:NamedThing	procollagen-proline 4-dioxygenase complex, alpha(I) type	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline).	got7fsn_ti	prolyl 4-hydroxylase complex (alpha(I)-type)|procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(I) type													cellular_component											owl:Class	
GO:0093002	biolink:NamedThing	response to nematicide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes.	got7fsn_ti	response to antihelmintic|response to nematocide													biological_process											owl:Class	
GO:0099122	biolink:NamedThing	RNA polymerase II C-terminal domain binding	Binding to the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.	got7fsn_ti	RNAP II C-terminal binding													molecular_function											owl:Class	
GO:0080074	biolink:NamedThing	spermidine:caffeoyl CoA N-acyltransferase activity	Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule.	got7fsn_ti							dhl	2009-04-13T04:17:23Z						molecular_function											owl:Class	
GO:0051959	biolink:NamedThing	dynein light intermediate chain binding	Binding to a light intermediate chain of the dynein complex.	got7fsn_ti														molecular_function											owl:Class	
GO:0039586	biolink:NamedThing	modulation by virus of host PP1 activity	The process in which a virus effects a change in host protein phosphatase-1 (PP1) activity, a serine/threonine phosphatase. Different viruses modulate host PP1 activity to remove phosphates from various cellular substrates and downregulate the host's antiviral response.	got7fsn_ti	modulation of host PP1 activity by virus|regulation by virus of host PP1 activity						bf	2012-05-04T02:11:05Z				VZ:803		biological_process											owl:Class	
GO:0039517	biolink:NamedThing	modulation by virus of host protein serine/threonine phosphatase activity	The process in which a virus effects a change in host protein serine/threonine phosphatase activity.	got7fsn_ti	modulation by virus of protein serine/threonine phosphatase activity in host|regulation by virus of host protein serine/threonine phosphatase activity						bf	2011-06-16T03:04:14Z						biological_process											owl:Class	
GO:0033784	biolink:NamedThing	senecionine N-oxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide.	got7fsn_ti	senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming) activity|SNO|senecionine monooxygenase (N-oxide-forming) activity											EC:1.14.13.101|RHEA:11420|KEGG_REACTION:R07373|MetaCyc:1.14.13.101-RXN		molecular_function											owl:Class	
GO:1901363	biolink:NamedThing	heterocyclic compound binding	Binding to heterocyclic compound.	got7fsn_ti							bf	2012-09-14T13:53:50Z						molecular_function											owl:Class	
GO:0015350	biolink:NamedThing	methotrexate transmembrane transporter activity	Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.	got7fsn_ti	methotrexate transporter activity													molecular_function											owl:Class	
GO:0030899	biolink:NamedThing	calcium-dependent ATPase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+).	got7fsn_ti														molecular_function											owl:Class	
GO:0033836	biolink:NamedThing	flavonol 7-O-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside.	got7fsn_ti	UDP-glucose:flavonol 7-O-glucosyltransferase activity|UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase activity											MetaCyc:2.4.1.237-RXN|RHEA:23164|EC:2.4.1.237		molecular_function											owl:Class	
GO:0043665	biolink:NamedThing	host peribacteroid fluid	The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0050389	biolink:NamedThing	uronolactonase activity	Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate.	got7fsn_ti	D-glucurono-6,2-lactone lactonohydrolase activity|glucuronolactonase activity											MetaCyc:URONOLACTONASE-RXN|EC:3.1.1.19|RHEA:13337		molecular_function											owl:Class	
GO:0019367	biolink:NamedThing	fatty acid elongation, saturated fatty acid	Elongation of a saturated fatty acid chain.	got7fsn_ti												MetaCyc:FASYN-ELONG-PWY		biological_process											owl:Class	
GO:0044838	biolink:NamedThing	cell quiescence	A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed.	got7fsn_ti	cellular quiescence|cell cycle quiescence|G0 phase|quiescence				Note that terminally differentiated cells in higher eukaryotes are typically quiescent but metabolically active. Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). Also, note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).		jl	2014-02-26T16:15:51Z						biological_process											owl:Class	
GO:0018252	biolink:NamedThing	peptide cross-linking via L-seryl-5-imidazolinone glycine	The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	got7fsn_ti	biosynthesis of protein-protein cross-link via L-seryl-5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via L-seryl-5-imidazolinone glycine				See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.							RESID:AA0184		biological_process											owl:Class	
GO:0043183	biolink:NamedThing	vascular endothelial growth factor receptor 1 binding	Binding to a vascular endothelial growth factor receptor 1.	got7fsn_ti	VEGFR 1 binding|VEGF receptor 1 binding|Flt-1 binding													molecular_function											owl:Class	
GO:0001049	biolink:NamedThing	RNA polymerase V core binding	Binding to RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing.	got7fsn_ti							krc	2010-09-23T01:41:08Z						molecular_function											owl:Class	
GO:0005728	biolink:NamedThing	extrachromosomal rDNA circle	Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats.	got7fsn_ti	extrachromosomal ribosomal DNA circle													cellular_component											owl:Class	
GO:0034673	biolink:NamedThing	inhibin-betaglycan-ActRII complex	A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B.	got7fsn_ti														cellular_component											owl:Class	
GO:0018746	biolink:NamedThing	phenanthrene-3,4-epoxide hydrolase activity	Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene.	got7fsn_ti												UM-BBD_reactionID:r0535		molecular_function											owl:Class	
GO:0106007	biolink:NamedThing	microtubule anchoring at cell cortex of cell tip	Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex.	got7fsn_ti							hjd	2017-04-19T15:12:45Z						biological_process											owl:Class	
GO:0102380	biolink:NamedThing	steviolbioside glucosyltransferase activity (rebaudioside B forming)	Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13516		molecular_function											owl:Class	
GO:0102259	biolink:NamedThing	1,2-diacylglycerol acylhydrolase activity	Catalysis of the reaction: H2O + a 1,2-diacyl-sn-glycerol = a monoglyceride + a fatty acid.	got7fsn_ti												MetaCyc:RXN-12434		molecular_function											owl:Class	
GO:0097687	biolink:NamedThing	dinoflagellate antapical horn	A horn-shaped dinoflagellate antapex found in thecate species.	got7fsn_ti							pr	2014-12-18T09:39:57Z						cellular_component											owl:Class	
GO:0008861	biolink:NamedThing	formate C-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.	got7fsn_ti	pyruvic formate-lyase activity|PFL|formate acetyltransferase activity|acetyl-CoA:formate C-acetyltransferase activity|pyruvate formate:lyase activity|pyruvate formate-lyase activity											RHEA:11844|EC:2.3.1.54|MetaCyc:PYRUVFORMLY-RXN		molecular_function											owl:Class	
GO:1990075	biolink:NamedThing	periciliary membrane compartment	A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis.	got7fsn_ti	PCMC						pr	2013-04-24T10:14:50Z						cellular_component											owl:Class	
GO:0010331	biolink:NamedThing	gibberellin binding	Binding to a gibberellin, a plant hormone that regulates aspects of plant growth.	got7fsn_ti	gibberellin receptor|gibberellic acid receptor													molecular_function											owl:Class	
GO:0032527	biolink:NamedThing	protein exit from endoplasmic reticulum	The directed movement of proteins from the endoplasmic reticulum.	got7fsn_ti	protein exit from ER|protein export from endoplasmic reticulum|protein export from ER													biological_process											owl:Class	
GO:0047517	biolink:NamedThing	1,4-beta-D-xylan synthase activity	Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1).	got7fsn_ti	xylan synthase activity|xylan synthetase activity|UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase activity|1,4-beta-xylan synthase activity|uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase activity											RHEA:15289|EC:2.4.2.24|MetaCyc:RXN-9104		molecular_function											owl:Class	
GO:0016544	biolink:NamedThing	male courtship behavior, tapping to detect pheromone	The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster.	got7fsn_ti	male courtship behaviour, tapping to detect pheromone|male courtship behavior, tapping|male courtship behaviour, tapping													biological_process											owl:Class	
GO:0090459	biolink:NamedThing	aspartate homeostasis	Any process involved in the maintenance of an internal steady state of aspartate within an organism or cell.	got7fsn_ti							tb	2012-09-24T14:22:02Z						biological_process											owl:Class	
GO:0036486	biolink:NamedThing	ventral trunk neural crest cell migration	The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta.	got7fsn_ti	ventral trunk NCC migration|trunk NCC migration within somite|trunk NCC migration through anterior sclerotome						bf	2014-08-26T15:30:16Z						biological_process											owl:Class	
GO:0030679	biolink:NamedThing	cyanelle ribonuclease P complex	A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.	got7fsn_ti	cyanelle RNase P complex													cellular_component											owl:Class	
GO:0034912	biolink:NamedThing	phthalate 3,4-cis-dihydrodiol dehydrogenase activity	Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+.	got7fsn_ti												MetaCyc:RXN5F9-56|UM-BBD_reactionID:r1445		molecular_function											owl:Class	
GO:1900205	biolink:NamedThing	apoptotic process involved in metanephric nephron tubule development	Any apoptotic process that is involved in metanephric nephron tubule development.	got7fsn_ti	programmed cell death by apoptosis of metanephric nephron tubule development|apoptotic programmed cell death of metanephric nephron tubule development|signaling (initiator) caspase activity of metanephric nephron tubule development|type I programmed cell death of metanephric nephron tubule development|apoptotic program of metanephric nephron tubule development|apoptotic cell death of metanephric nephron tubule development|apoptotic process of metanephric nephron tubule development|apoptosis of metanephric nephron tubule development						yaf	2012-03-21T01:21:45Z						biological_process											owl:Class	
GO:0052620	biolink:NamedThing	thymine dehydrogenase activity	Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2.	got7fsn_ti												RHEA:13469|MetaCyc:RXN-8646|EC:1.17.99.4		molecular_function											owl:Class	
GO:0050114	biolink:NamedThing	myo-inosose-2 dehydratase activity	Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O.	got7fsn_ti	2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase activity|2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming)|inosose 2,3-dehydratase activity|ketoinositol dehydratase activity											RHEA:14065|EC:4.2.1.44|MetaCyc:MYO-INOSOSE-2-DEHYDRATASE-RXN|KEGG_REACTION:R02782		molecular_function											owl:Class	
GO:0004324	biolink:NamedThing	ferredoxin-NADP+ reductase activity	Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+.	got7fsn_ti	ferredoxin-TPN reductase activity|ferredoxin-NADP oxidoreductase activity|ferredoxin-NADP reductase activity|ferredoxin-nicotinamide adenine dinucleotide phosphate reductase activity|ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase activity|reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase activity|TPNH-ferredoxin reductase activity|ferredoxin:NADP+ oxidoreductase activity|NADPH:ferredoxin oxidoreductase activity|ferredoxin-NADP-oxidoreductase activity|NADP:ferredoxin oxidoreductase activity				Note that this term specifically refers to the reaction proceeding in the direction shown; it should therefore be used to annotate gene products that catalyze the oxidation of reduced ferredoxin or adrenodoxin; also consider annotating to the molecular function term 'NADPH-adrenodoxin reductase activity ; GO:0015039'.							RHEA:20125|EC:1.18.1.2|MetaCyc:1.18.1.2-RXN		molecular_function											owl:Class	
GO:0052763	biolink:NamedThing	ulvan lyase activity	Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.	got7fsn_ti							ai	2011-09-29T03:39:23Z						molecular_function											owl:Class	
GO:0070355	biolink:NamedThing	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).	got7fsn_ti	STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2-CPLX2 complex|SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2, CPLX2)													cellular_component											owl:Class	
GO:0072565	biolink:NamedThing	endothelial microparticle formation	The cellular component organization process in which microparticles bud off from an endothelial cell.	got7fsn_ti	endothelial microparticle generation|endothelial microparticle release						mah	2011-01-28T02:21:58Z						biological_process											owl:Class	
GO:0061912	biolink:NamedThing	selective autophagy	The macroautophagy process in which specific structures are targeted by the autophagy process.	got7fsn_ti							dph	2017-07-07T17:27:37Z						biological_process											owl:Class	
GO:0060747	biolink:NamedThing	oral incubation	A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.	got7fsn_ti							dph	2009-06-22T09:08:58Z						biological_process											owl:Class	
GO:0030373	biolink:NamedThing	high molecular weight B cell growth factor receptor activity	Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity.	got7fsn_ti	high molecular weight B-lymphocyte growth factor receptor activity|high molecular weight B-cell growth factor receptor activity|HMW-BCGF receptor|high molecular weight B lymphocyte growth factor receptor activity													molecular_function											owl:Class	
GO:0071193	biolink:NamedThing	Kv4.2-KChIP2 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.	got7fsn_ti							mah	2009-11-23T04:58:09Z				CORUM:607		cellular_component											owl:Class	
GO:0090009	biolink:NamedThing	primitive streak formation	The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.	got7fsn_ti							tb	2009-07-29T10:31:31Z						biological_process											owl:Class	
GO:2000943	biolink:NamedThing	negative regulation of amylopectin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process.	got7fsn_ti	negative regulation of Amylopectin metabolism						tt	2011-08-01T02:10:32Z						biological_process											owl:Class	
GO:0031624	biolink:NamedThing	ubiquitin conjugating enzyme binding	Binding to a ubiquitin conjugating enzyme, any of the E2 proteins.	got7fsn_ti														molecular_function											owl:Class	
GO:0004774	biolink:NamedThing	succinate-CoA ligase activity	Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA.	got7fsn_ti														molecular_function											owl:Class	
GO:0010483	biolink:NamedThing	pollen tube reception	Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells.	got7fsn_ti														biological_process											owl:Class	
GO:0102571	biolink:NamedThing	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [glycoprotein]-(L-serine/L-threonine).	got7fsn_ti												MetaCyc:RXN-15215|EC:3.2.1.169		molecular_function											owl:Class	
GO:0004142	biolink:NamedThing	diacylglycerol cholinephosphotransferase activity	Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.	got7fsn_ti	phosphocholine diacylglyceroltransferase activity|alkylacylglycerol cholinephosphotransferase activity|alkylacylglycerol choline phosphotransferase activity|1-alkyl-2-acetylglycerol cholinephosphotransferase activity|cytidine diphosphocholine glyceride transferase activity|cytidine diphosphorylcholine diglyceride transferase activity|diacylglycerol choline phosphotransferase activity|phosphorylcholine--glyceride transferase activity|CDP-choline diglyceride phosphotransferase activity|CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity|1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity|1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity|cholinephosphotransferase activity|sn-1,2-diacylglycerol cholinephosphotransferase activity|CPT											Reactome:R-HSA-1482961|EC:2.7.8.2|MetaCyc:RXN-5781|Reactome:R-HSA-1482973|RHEA:32939		molecular_function											owl:Class	
GO:0045023	biolink:NamedThing	G0 to G1 transition	The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.	got7fsn_ti														biological_process											owl:Class	
GO:0060020	biolink:NamedThing	Bergmann glial cell differentiation	The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0019701	biolink:NamedThing	peptidyl-arginine N5-methylation	The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine.	got7fsn_ti	peptidyl-arginine delta-N-methylation											RESID:AA0305		biological_process											owl:Class	
GO:0047505	biolink:NamedThing	(-)-menthol monooxygenase activity	Catalysis of the reaction: (-)-menthol + H(+) + NADPH + O(2) = 1,4-menthane-3,8-diol + H(2)O + NADP(+).	got7fsn_ti	l-menthol monooxygenase activity|(-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)											EC:1.14.13.46|RHEA:11648|KEGG_REACTION:R02178|MetaCyc:--MENTHOL-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0140552	biolink:NamedThing	TEAD-YAP complex	A transcription factor complex that is composed of the one DNA binding protein of the TEAD family and the transcriptional coactivator YAP.	got7fsn_ti	TEAD-1-YAP complex|TEAD-3-YAP complex|TEAD-2 multiprotein complex|TEAD-4-YAP complex|TEAD-2-YAP complex	https://github.com/geneontology/go-ontology/issues/9300					pg	2020-11-17T07:05:23Z			GO:0071150|GO:0071147|GO:0071151|GO:0071149|GO:0071148	CORUM:2870		cellular_component											owl:Class	
GO:1990173	biolink:NamedThing	protein localization to nucleoplasm	A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.	got7fsn_ti	nucleolus to nucleoplasm transport|protein localisation to nucleoplasm	https://github.com/geneontology/go-ontology/issues/14690					mah	2013-08-23T15:01:16Z			GO:0032066			biological_process											owl:Class	
GO:0034504	biolink:NamedThing	protein localization to nucleus	A process in which a protein transports or maintains the localization of another protein to the nucleus.	got7fsn_ti	protein localisation to nucleus|protein targeting to nucleus|protein localization in cell nucleus|protein localization in nucleus							2012-11-07T15:45:54Z			GO:0044744			biological_process											owl:Class	
GO:0014074	biolink:NamedThing	response to purine-containing compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.	got7fsn_ti	response to purine													biological_process											owl:Class	
GO:0018645	biolink:NamedThing	alkene monooxygenase activity	Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O.	got7fsn_ti	alkene epoxygenase activity|alkene,NADH:oxygen oxidoreductase activity											EC:1.14.13.69|RHEA:11792|MetaCyc:1.14.13.69-RXN|UM-BBD_enzymeID:e0039		molecular_function											owl:Class	
GO:0033850	biolink:NamedThing	Z-farnesyl diphosphate synthase activity	Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate.	got7fsn_ti	geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase activity|(Z)-farnesyl diphosphate synthase activity											EC:2.5.1.68|RHEA:23300|MetaCyc:2.5.1.68-RXN|KEGG_REACTION:R08528		molecular_function											owl:Class	
GO:0050047	biolink:NamedThing	leucine 2,3-aminomutase activity	Catalysis of the reaction: L-leucine = (3R)-beta-leucine.	got7fsn_ti	(2S)-alpha-leucine 2,3-aminomutase activity											KEGG_REACTION:R01091|RHEA:10284|EC:5.4.3.7|MetaCyc:LEUCINE-23-AMINOMUTASE-RXN		molecular_function											owl:Class	
GO:0018738	biolink:NamedThing	S-formylglutathione hydrolase activity	Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+).	got7fsn_ti												KEGG_REACTION:R00527|MetaCyc:S-FORMYLGLUTATHIONE-HYDROLASE-RXN|EC:3.1.2.12|UM-BBD_reactionID:r0241|RHEA:14961|Reactome:R-HSA-5693724		molecular_function											owl:Class	
GO:0050348	biolink:NamedThing	trehalose O-mycolyltransferase activity	Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose.	got7fsn_ti	alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase activity|alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase activity											RHEA:23472|EC:2.3.1.122|KEGG_REACTION:R07248|MetaCyc:RXN1G-874		molecular_function											owl:Class	
GO:0097622	biolink:NamedThing	cytoplasmic translational elongation through polyproline stretches	The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm.	got7fsn_ti							pr	2014-08-06T16:29:10Z						biological_process											owl:Class	
GO:0034432	biolink:NamedThing	bis(5'-adenosyl)-pentaphosphatase activity	Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.	got7fsn_ti	AP-5-A hydrolase activity|AP5A hydrolase activity|Ap5a pyrophosphohydrolase activity|diadenosine 5',5'''-P1,P6-pentaphosphate hydrolase activity|AP(5)A hydrolase activity													molecular_function											owl:Class	
GO:0047542	biolink:NamedThing	2-furoyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-furoyl-CoA + A + H(2)O = 5-hydroxy-2-furoyl-CoA + AH(2) + H(+).	got7fsn_ti	2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating)|2-furoyl coenzyme A dehydrogenase activity|2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)|2-furoyl coenzyme A hydroxylase activity|furoyl-CoA hydroxylase activity											KEGG_REACTION:R02987|RHEA:21480|MetaCyc:2-FUROYL-COA-DEHYDROGENASE-RXN|EC:1.3.99.8		molecular_function											owl:Class	
GO:0017059	biolink:NamedThing	serine C-palmitoyltransferase complex	An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine.	got7fsn_ti														cellular_component											owl:Class	
GO:0031211	biolink:NamedThing	endoplasmic reticulum palmitoyltransferase complex	A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue.	got7fsn_ti														cellular_component											owl:Class	
GO:0042382	biolink:NamedThing	paraspeckles	Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei.	got7fsn_ti												Wikipedia:Paraspeckle		cellular_component											owl:Class	
GO:0015829	biolink:NamedThing	valine transport	The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-valine transport													biological_process											owl:Class	
GO:0060930	biolink:NamedThing	sinoatrial node cell fate commitment	The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node.	got7fsn_ti	sinus node cell commitment|SAN cell commitment|SA node cell commitment						dph	2009-09-29T12:03:38Z						biological_process											owl:Class	
GO:0050226	biolink:NamedThing	psychosine sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate.	got7fsn_ti	3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase activity|PAPS:psychosine sulphotransferase activity|3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase activity|psychosine sulphotransferase activity											MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN|RHEA:14137|EC:2.8.2.13		molecular_function											owl:Class	
GO:0003297	biolink:NamedThing	heart wedging	The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart.	got7fsn_ti							dph	2009-10-22T08:52:58Z						biological_process											owl:Class	
GO:0002054	biolink:NamedThing	nucleobase binding	Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.	got7fsn_ti														molecular_function											owl:Class	
GO:0004020	biolink:NamedThing	adenylylsulfate kinase activity	Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.	got7fsn_ti	adenosine-5'-phosphosulfate-3'-phosphokinase activity|APS kinase activity|adenosine-5'-phosphosulfate 3'-phosphotransferase activity|adenosine-5'-phosphosulphate 3'-phosphotransferase activity|adenosine 5'-phosphosulfate kinase activity|adenylyl-sulfate kinase activity|adenylylsulfate kinase (phosphorylating)|5'-phosphoadenosine sulfate kinase activity|adenylyl-sulphate kinase activity|adenosine phosphosulfate kinase activity|ATP:adenylyl-sulfate 3'-phosphotransferase activity|adenosine phosphosulfokinase activity											Reactome:R-HSA-3560785|EC:2.7.1.25|Reactome:R-HSA-174389|MetaCyc:ADENYLYLSULFKIN-RXN|RHEA:24152		molecular_function											owl:Class	
GO:1900204	biolink:NamedThing	apoptotic process involved in metanephric collecting duct development	Any apoptotic process that is involved in metanephric collecting duct development.	got7fsn_ti	programmed cell death by apoptosis of metanephric collecting duct development|apoptosis of metanephric collecting duct development|apoptotic process of metanephric collecting duct development|apoptotic programmed cell death of metanephric collecting duct development|apoptotic program of metanephric collecting duct development|apoptotic cell death of metanephric collecting duct development|signaling (initiator) caspase activity of metanephric collecting duct development|type I programmed cell death of metanephric collecting duct development						yaf	2012-03-21T01:21:32Z						biological_process											owl:Class	
GO:0018129	biolink:NamedThing	peptidyl-oxazoline dehydrogenase activity	Catalysis of the reduction of a peptide-linked oxazoline to oxazole.	got7fsn_ti														molecular_function											owl:Class	
GO:0140372	biolink:NamedThing	histone H3 ubiquitination	The modification of histone H3 by the addition of one or more ubiquitin groups.	got7fsn_ti	histone H3 ubiquitylation						pg	2019-10-03T15:29:54Z						biological_process											owl:Class	
GO:0004604	biolink:NamedThing	phosphoadenylyl-sulfate reductase (thioredoxin) activity	Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.	got7fsn_ti	thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase activity|thioredoxin:3'-phospho-adenylylsulfate reductase activity|adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)|PAdoPS reductase activity|PAPS reductase activity|PAPS reductase, thioredoxin-dependent activity|adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)|phosphoadenylyl-sulphate reductase (thioredoxin) activity|PAPS sulfotransferase activity|phosphoadenosine-phosphosulfate reductase activity|3'-phosphoadenylylsulfate reductase activity											EC:1.8.4.8|MetaCyc:1.8.4.8-RXN|KEGG_REACTION:R02021|RHEA:11724		molecular_function											owl:Class	
GO:0005124	biolink:NamedThing	scavenger receptor binding	Binding to scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.	got7fsn_ti	scavenger receptor ligand													molecular_function											owl:Class	
GO:0071184	biolink:NamedThing	protocadherin-alpha-v4-protocadherin-gamma-a1 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.	got7fsn_ti	Pcdhga1-Pcdha4 complex						mah	2009-11-23T04:11:47Z						cellular_component											owl:Class	
GO:0098768	biolink:NamedThing	meiotic prometaphase I	The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.	got7fsn_ti					This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0047074	biolink:NamedThing	4-hydroxycatechol 1,2-dioxygenase activity	Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate.	got7fsn_ti												MetaCyc:RXN-10137|RHEA:35595|MetaCyc:R308-RXN|EC:1.13.11.37		molecular_function											owl:Class	
GO:0007412	biolink:NamedThing	axon target recognition	The process in which an axon recognizes and binds to a set of cells with which it may form stable connections.	got7fsn_ti														biological_process											owl:Class	
GO:0062152	biolink:NamedThing	mRNA (cytidine-5-)-methyltransferase activity	Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine.	got7fsn_ti	mRNA (cytosine-5-)-methyltransferase activity						dph	2019-09-18T14:40:32Z				RHEA:61464		molecular_function											owl:Class	
GO:0034522	biolink:NamedThing	cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0774		molecular_function											owl:Class	
GO:0003137	biolink:NamedThing	Notch signaling pathway involved in heart induction	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.	got7fsn_ti	Notch signalling pathway involved in heart induction						tb	2009-09-22T03:28:42Z						biological_process											owl:Class	
GO:0007219	biolink:NamedThing	Notch signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	Notch receptor signalling pathway|N signalling pathway|Notch receptor signaling pathway|Notch-receptor signalling pathway|N signaling pathway|Notch-receptor signaling pathway|Notch signalling pathway										GO:0030179	Wikipedia:Notch_signaling_pathway		biological_process											owl:Class	
GO:0043834	biolink:NamedThing	trimethylamine methyltransferase activity	Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine.	got7fsn_ti	trimethylamine:corrinoid methyltransferase activity|MT1|trimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|TMA methyltransferase 1|mttB1				This function is the first step in the pathway of methanogenesis from trimethylamine.							MetaCyc:RXN-8102|RHEA:39287|EC:2.1.1.250		molecular_function											owl:Class	
GO:0008935	biolink:NamedThing	1,4-dihydroxy-2-naphthoyl-CoA synthase activity	Catalysis of the reaction: 2-succinylbenzoyl-CoA + H+ = 1,4-dihydroxy-2-naphthoyl-CoA + H2O.	got7fsn_ti	naphthoate synthase activity|dihydroxynaphthoate synthase activity|DHNA synthetase activity|dihydroxynaphthoic acid synthetase activity|O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing) activity	https://github.com/geneontology/go-ontology/issues/21763										MetaCyc:NAPHTHOATE-SYN-RXN|EC:4.1.3.36|RHEA:26562|KEGG_REACTION:R04150		molecular_function											owl:Class	
GO:0102036	biolink:NamedThing	methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity	Catalysis of the reaction: a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] <=> an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein].	got7fsn_ti												RHEA:45200|EC:2.1.1.258|MetaCyc:METHCOCLTH-RXN		molecular_function											owl:Class	
GO:0051273	biolink:NamedThing	beta-glucan metabolic process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.	got7fsn_ti	beta-glucan metabolism													biological_process											owl:Class	
GO:2001000	biolink:NamedThing	regulation of xylan catabolic process	Any process that modulates the frequency, rate or extent of xylan catabolic process.	got7fsn_ti	regulation of xylan catabolism|regulation of xylan degradation|regulation of xylan breakdown						tt	2011-08-08T03:23:13Z						biological_process											owl:Class	
GO:0045158	biolink:NamedThing	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity	Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II.	got7fsn_ti	cytochrome|cytochrome b6|cytochrome f|cytochrome b/b6													molecular_function											owl:Class	
GO:0045130	biolink:NamedThing	keratan sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.	got7fsn_ti	keratan sulfate Gal-6-sulfotransferase activity|3'-phosphoadenylylsulfate:keratan sulfotransferase activity|keratan sulphotransferase activity|3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase activity|3'-phosphoadenylyl keratan sulfotransferase activity|keratan sulfate sulfotransferase activity											MetaCyc:KERATAN-SULFOTRANSFERASE-RXN|EC:2.8.2.21|Reactome:R-HSA-2046175		molecular_function											owl:Class	
GO:0051008	biolink:NamedThing	Hsp27 protein binding	Binding to Hsp27 proteins, a lightweight heat shock protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0009849	biolink:NamedThing	tryptophan-independent indoleacetic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan.	got7fsn_ti	tryptophan-independent IAA biosynthetic process|tryptophan-independent indoleacetic acid formation|tryptophan-independent indoleacetic acid biosynthesis|indoleacetic acid biosynthesis, tryptophan-independent|indoleacetic acid biosynthetic process, tryptophan-independent|tryptophan-independent indoleacetic acid synthesis|tryptophan-independent indoleacetic acid anabolism											MetaCyc:PWY-581		biological_process											owl:Class	
GO:0031385	biolink:NamedThing	regulation of termination of mating projection growth	Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0031383	biolink:NamedThing	regulation of mating projection assembly	Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi.	got7fsn_ti	regulation of mating projection biogenesis													biological_process											owl:Class	
GO:1990733	biolink:NamedThing	titin-telethonin complex	A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils.	got7fsn_ti	Titin-Tcap complex				An example of this are TTN and TCAP in human (UniProt symbols Q8WZ42 and O15273 respectively) in PMID:16407954 (inferred from direct assay).		ame	2015-04-24T14:57:08Z						cellular_component											owl:Class	
GO:0071461	biolink:NamedThing	cellular response to redox state	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.	got7fsn_ti	cellular redox signal response						mah	2009-12-18T11:30:21Z						biological_process											owl:Class	
GO:0016936	biolink:NamedThing	galactoside binding	Binding to a glycoside in which the sugar group is galactose.	got7fsn_ti														molecular_function											owl:Class	
GO:0044076	biolink:NamedThing	positive regulation by symbiont of host vacuole organization	The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism.	got7fsn_ti	positive regulation by symbiont of host vacuole biogenesis|positive regulation by symbiont of host vacuole organisation|positive regulation of host vacuole organization by symbiont													biological_process											owl:Class	
GO:0008792	biolink:NamedThing	arginine decarboxylase activity	Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2).	got7fsn_ti	L-arginine carboxy-lyase (agmatine-forming)|L-arginine carboxy-lyase activity|SpeA											EC:4.1.1.19|Reactome:R-HSA-350598|KEGG_REACTION:R00566|RHEA:17641|MetaCyc:ARGDECARBOX-RXN		molecular_function											owl:Class	
GO:0047964	biolink:NamedThing	glyoxylate reductase (NAD+) activity	Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH.	got7fsn_ti	glyoxylic acid reductase activity|glycolate reductase activity|NADH-dependent glyoxylate reductase activity											RHEA:18229|MetaCyc:GLYCOLATE-REDUCTASE-RXN|EC:1.1.1.26		molecular_function											owl:Class	
GO:0010328	biolink:NamedThing	auxin influx transmembrane transporter activity	Enables the transfer of auxin, from one side of a membrane to the other, into a cell.	got7fsn_ti	auxin influx facilitator													molecular_function											owl:Class	
GO:0140541	biolink:NamedThing	piRNA transcription	The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	got7fsn_ti	Piwi-associated RNA transcription|PIWI-interacting RNA transcription	https://github.com/geneontology/go-ontology/issues/19530					pg	2020-11-09T16:53:25Z						biological_process											owl:Class	
GO:0005432	biolink:NamedThing	calcium:sodium antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).	got7fsn_ti	sodium/calcium exchanger|sodium:calcium exchange|mitochondrial sodium/calcium ion exchange											Reactome:R-HSA-8949703|RHEA:29255|Reactome:R-HSA-8949688|Reactome:R-HSA-425661		molecular_function											owl:Class	
GO:0002748	biolink:NamedThing	antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen	Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).	got7fsn_ti	antigen processing and presentation initiated by PRR mediated uptake of antigen|antigen processing and presentation initiated by PAMP receptor mediated uptake of antigen													biological_process											owl:Class	
GO:0061921	biolink:NamedThing	peptidyl-lysine propionylation	The propionylation of peptidyl-lysine.	got7fsn_ti							dph	2017-08-02T13:37:14Z						biological_process											owl:Class	
GO:0044584	biolink:NamedThing	cellodextrin binding	Binding to a cellodextrin, a glucose polymer of 2 or more glucose monomers.	got7fsn_ti							jl	2012-04-24T04:52:05Z						molecular_function											owl:Class	
GO:0018376	biolink:NamedThing	peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine	The hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).	got7fsn_ti					See also the molecular function term 'peptide-aspartate beta-dioxygenase activity ; GO:0004597'.							RESID:AA0026		biological_process											owl:Class	
GO:0035551	biolink:NamedThing	protein initiator methionine removal involved in protein maturation	Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein.	got7fsn_ti							bf	2010-05-13T04:29:05Z						biological_process											owl:Class	
GO:0072581	biolink:NamedThing	protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine	The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).	got7fsn_ti							mah	2011-02-07T11:51:02Z						biological_process											owl:Class	
GO:0051717	biolink:NamedThing	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.	got7fsn_ti	inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity|inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity|inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity											Reactome:R-HSA-1855200|Reactome:R-HSA-1855205|MetaCyc:3.1.3.62-RXN		molecular_function											owl:Class	
GO:0035654	biolink:NamedThing	clathrin-coated vesicle cargo loading, AP-3-mediated	Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle.	got7fsn_ti	cargo loading into clathrin-coated vesicle, AP-3-mediated						bf	2011-01-25T11:02:30Z						biological_process											owl:Class	
GO:0090564	biolink:NamedThing	protein-phosphocysteine-glucose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	got7fsn_ti							tb	2014-04-08T15:03:08Z						molecular_function											owl:Class	
GO:0002043	biolink:NamedThing	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis.	got7fsn_ti	blood vessel endothelial cell proliferation during sprouting angiogenesis													biological_process											owl:Class	
GO:0071111	biolink:NamedThing	cyclic-guanylate-specific phosphodiesterase activity	Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+).	got7fsn_ti	VieA|cyclic bis(3->5')diguanylate phosphodiesterase activity|PDEA1|c-di-GMP-specific phosphodiesterase activity|c-di-GMP phosphodiesterase activity|phosphodiesterase A1 activity						mah	2009-11-13T02:10:39Z				KEGG_REACTION:R08991|EC:3.1.4.52|MetaCyc:RXN0-4181|RHEA:24902		molecular_function											owl:Class	
GO:0102429	biolink:NamedThing	genistein-3-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: genistin + UDP-alpha-D-glucose <=> genistin 7-gentiobioside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13831		molecular_function											owl:Class	
GO:0071209	biolink:NamedThing	U7 snRNA binding	Binding to a U7 small nuclear RNA (U7 snRNA).	got7fsn_ti					Note that this term may be useful for annotating other small nuclear RNAs (snRNAs).		mah	2009-11-25T01:46:50Z						molecular_function											owl:Class	
GO:0120108	biolink:NamedThing	DNA-3'-diphospho-5'-guanosine diphosphatase	Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H(2)O <=> (DNA)-3'-phosphate + GMP.	got7fsn_ti	DNA-3'pp5'G guanylate hydrolase						krc	2017-10-17T22:12:59Z				EC:3.6.1.72|RHEA:52140		molecular_function											owl:Class	
GO:0046946	biolink:NamedThing	hydroxylysine metabolic process	The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases.	got7fsn_ti	hydroxylysine metabolism													biological_process											owl:Class	
GO:0032580	biolink:NamedThing	Golgi cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.	got7fsn_ti	Golgi stack membrane													cellular_component											owl:Class	
GO:0017040	biolink:NamedThing	N-acylsphingosine amidohydrolase activity	Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine.	got7fsn_ti	acylsphingosine deacylase activity|glycosphingolipid ceramide deacylase|N-acylsphingosine amidohydrolase activity											Reactome:R-HSA-1606583|Reactome:R-HSA-428231|RHEA:20856|EC:3.5.1.23|Reactome:R-HSA-428205|Reactome:R-HSA-1606602|MetaCyc:CERAMIDASE-RXN		molecular_function											owl:Class	
GO:0008726	biolink:NamedThing	alkanesulfonate monooxygenase activity	Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN.	got7fsn_ti	FMNH2-dependent aliphatic sulfonate monooxygenase activity|FMNH(2)-dependent alkanesulfonate monooxygenase activity|FMNH(2)-dependent aliphatic sulfonate monooxygenase activity|alkanesulfonate, reduced-FMN:oxygen oxidoreductase activity|sulfate starvation-induced protein 6 activity|SsuD|alkanesulphonate monooxygenase activity											MetaCyc:RXN0-280|EC:1.14.14.5|RHEA:23064		molecular_function											owl:Class	
GO:0050581	biolink:NamedThing	D-mannitol oxidase activity	Catalysis of the reaction: mannitol + O2 = mannose + H2O2.	got7fsn_ti	mannitol oxidase activity|D-arabinitol oxidase activity|mannitol:oxygen oxidoreductase (cyclizing)|D-arabitol oxidase activity											RHEA:18513|MetaCyc:1.1.3.40-RXN|EC:1.1.3.40		molecular_function											owl:Class	
GO:0004083	biolink:NamedThing	bisphosphoglycerate 2-phosphatase activity	Catalysis of the reaction: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate.	got7fsn_ti	2,3-bisphospho-D-glycerate 2-phosphohydrolase activity											KEGG_REACTION:R01516|RHEA:21904|MetaCyc:BISPHOSPHOGLYCERATE-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0046336	biolink:NamedThing	ethanolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).	got7fsn_ti	ethanolamine degradation|ethanolamine catabolism|ethanolamine breakdown													biological_process											owl:Class	
GO:0140562	biolink:NamedThing	EGF-domain serine xylosyltransferase activity	Catalyses the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16869					pg	2020-11-25T14:30:56Z				RHEA:62016|EC:2.4.2.63		molecular_function											owl:Class	
GO:0047886	biolink:NamedThing	farnesol dehydrogenase activity	Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP(+) = 2-trans,6-trans-farnesal + H(+) + NADPH.	got7fsn_ti	NADP-farnesol dehydrogenase activity|farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase activity											RHEA:14697|EC:1.1.1.216|KEGG_REACTION:R03264|MetaCyc:FARNESOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0050026	biolink:NamedThing	L-glycol dehydrogenase activity	Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+.	got7fsn_ti	L-glycol:NAD(P)+ oxidoreductase activity|glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity|L-(+)-glycol:NAD(P) oxidoreductase activity|L-glycol:NAD(P) dehydrogenase activity											MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN|EC:1.1.1.185		molecular_function											owl:Class	
GO:1990120	biolink:NamedThing	messenger ribonucleoprotein complex assembly	The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.	got7fsn_ti	mRNP assembly|messenger ribonucleoprotein assembly|mRNP complex assembly|mRNA-protein complex assembly						rb	2013-06-11T21:18:20Z						biological_process											owl:Class	
GO:2001042	biolink:NamedThing	negative regulation of septum digestion after cytokinesis	Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.	got7fsn_ti	negative regulation of cytokinetic cell separation						mcc	2011-08-30T05:16:55Z						biological_process											owl:Class	
GO:0070139	biolink:NamedThing	SUMO-specific endopeptidase activity	Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.	got7fsn_ti												Reactome:R-HSA-2993763|Reactome:R-HSA-2990840|Reactome:R-HSA-2990842		molecular_function											owl:Class	
GO:0050138	biolink:NamedThing	nicotinate dehydrogenase activity	Catalysis of the reaction: H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH.	got7fsn_ti	nicotinate:NADP+ 6-oxidoreductase (hydroxylating)|nicotinate hydroxylase activity|nicotinic acid hydroxylase activity											RHEA:12236|MetaCyc:NICOTINATE-DEHYDROGENASE-RXN|EC:1.17.1.5|KEGG_REACTION:R01720|MetaCyc:RXN-7637		molecular_function											owl:Class	
GO:0021824	biolink:NamedThing	cerebral cortex tangential migration using cell-axon interactions	The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.	got7fsn_ti														biological_process											owl:Class	
GO:0050606	biolink:NamedThing	4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity	Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH.	got7fsn_ti	4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP(+) oxidoreductase activity|2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase activity|4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase activity|alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase activity											KEGG_REACTION:R04279|EC:1.1.1.312|RHEA:29587|MetaCyc:1.2.1.45-RXN		molecular_function											owl:Class	
GO:0042305	biolink:NamedThing	specification of segmental identity, mandibular segment	The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti					See also the fly_anatomy.ontology term 'mandibular segment ; FBbt:00000012'.									biological_process											owl:Class	
GO:0050173	biolink:NamedThing	phenylalanine adenylyltransferase activity	Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+).	got7fsn_ti	ATP:L-phenylalanine adenylyltransferase activity|ATP:phenylalanine adenylyltransferase activity|L-phenylalanine adenylyltransferase activity											MetaCyc:PHENYLALANINE-ADENYLYLTRANSFERASE-RXN|RHEA:17189|EC:2.7.7.54|KEGG_REACTION:R00687		molecular_function											owl:Class	
GO:0052883	biolink:NamedThing	tyrosine ammonia-lyase activity	Catalysis of the reaction: L-tyrosine = NH(4)(+) + trans-4-coumarate.	got7fsn_ti	TAL activity|tyrase activity|L-tyrosine ammonia-lyase activity											RHEA:24906|EC:4.3.1.25|EC:4.3.1.23		molecular_function											owl:Class	
GO:0009116	biolink:NamedThing	nucleoside metabolic process	The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).	got7fsn_ti	nucleoside metabolism													biological_process											owl:Class	
GO:0006105	biolink:NamedThing	succinate metabolic process	The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.	got7fsn_ti	succinate metabolism													biological_process											owl:Class	
GO:0102948	biolink:NamedThing	luteolin C-glucosyltransferase activity	Catalysis of the reaction: 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate + a glucosylated glucose acceptor = isoorientin + a non glucosylated glucose acceptor.	got7fsn_ti												MetaCyc:RXN-9081		molecular_function											owl:Class	
GO:0046936	biolink:NamedThing	2'-deoxyadenosine deaminase activity	Catalysis of the reaction: 2'-deoxyadenosine + H2O = deoxyinosine + NH3.	got7fsn_ti	deoxyadenosine deaminase reaction											MetaCyc:ADDALT-RXN|RHEA:28190		molecular_function											owl:Class	
GO:0014914	biolink:NamedThing	myoblast maturation involved in muscle regeneration	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0048628	biolink:NamedThing	myoblast maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0047584	biolink:NamedThing	4-oxalmesaconate hydratase activity	Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(2)O.	got7fsn_ti	2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase [(E)-4-oxobut-1-ene-1,2,4-tricarboxylate-forming]|gamma-oxalmesaconate hydratase activity|oxalmesaconate hydratase activity|4-carboxy-2-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity|4-carboxy-2-oxohexenedioate hydratase activity|2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity											MetaCyc:RXN-2463|EC:4.2.1.83|KEGG_REACTION:R04478|RHEA:17401		molecular_function											owl:Class	
GO:0106096	biolink:NamedThing	response to ceramide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.	got7fsn_ti							hjd	2018-02-12T19:48:43Z						biological_process											owl:Class	
GO:0033993	biolink:NamedThing	response to lipid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0052881	biolink:NamedThing	4-hydroxyphenylacetate 3-monooxygenase activity	Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + FAD + H(+) + H(2)O.	got7fsn_ti	4 HPA 3-hydroxylase activity|4-hydroxyphenylacetic acid-3-hydroxylase activity|p-hydroxyphenylacetate 3-hydroxylase activity|4-hydroxyphenylacetate,FADH:oxygen oxidoreductase (3-hydroxylating) activity|p-hydroxyphenylacetate 3-hydroxylase (FAD) activity|p-hydroxyphenylacetate hydroxylase activity|p-hydroxyphenylacetate hydroxylase (FAD) activity											UM-BBD_reactionID:r0301|EC:1.14.14.9|RHEA:30595|MetaCyc:RXN-8505		molecular_function											owl:Class	
GO:0097270	biolink:NamedThing	dishabituation	The temporary recovery of response to a stimulus when a novel stimulus is added.	got7fsn_ti							pr	2012-03-20T01:39:25Z						biological_process											owl:Class	
GO:0048188	biolink:NamedThing	Set1C/COMPASS complex	A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.	got7fsn_ti	Set1/COMPASS complex|Set1C|COMPASS complex													cellular_component											owl:Class	
GO:0018234	biolink:NamedThing	peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine	The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase.	got7fsn_ti												RESID:AA0113		biological_process											owl:Class	
GO:0004052	biolink:NamedThing	arachidonate 12(S)-lipoxygenase activity	Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.	got7fsn_ti	C-12 lipoxygenase activity|12Delta-lipoxygenase activity|delta12-lipoxygenase activity|12S-lipoxygenase activity|arachidonate:oxygen 12-oxidoreductase activity|12-lipoxygenase activity|LTA4 synthase activity|leukotriene A4 synthase											Reactome:R-HSA-9024983|Reactome:R-HSA-2161948|MetaCyc:ARACHIDONATE-12-LIPOXYGENASE-RXN|Reactome:R-HSA-2161964|Reactome:R-HSA-9026006|Reactome:R-HSA-9025957|Reactome:R-HSA-2161950|EC:1.13.11.31|KEGG_REACTION:R01596|Reactome:R-HSA-9026007|RHEA:10428		molecular_function											owl:Class	
GO:0007142	biolink:NamedThing	male meiosis II	A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.	got7fsn_ti	male meiosis II nuclear division													biological_process											owl:Class	
GO:0060313	biolink:NamedThing	negative regulation of blood vessel remodeling	Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.	got7fsn_ti	inhibition of blood vessel remodeling|down-regulation of blood vessel remodeling													biological_process											owl:Class	
GO:0047353	biolink:NamedThing	N-methylphosphoethanolamine cytidylyltransferase activity	Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate.	got7fsn_ti	CTP:P-MEA cytidylyltransferase activity|CTP:N-methylethanolamine-phosphate cytidylyltransferase activity|CTP:N-methylphosphoethanolamine cytidylyltransferase activity|monomethylethanolamine phosphate cytidylyltransferase activity											EC:2.7.7.57|RHEA:10576|KEGG_REACTION:R03375|MetaCyc:2.7.7.57-RXN		molecular_function											owl:Class	
GO:0140702	biolink:NamedThing	cyclic GMP-AMP binding	Binding to cyclic GMP-AMP (cGAMP) nucleotide.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21980					pg	2021-08-27T05:39:31Z						molecular_function											owl:Class	
GO:0032457	biolink:NamedThing	fast endocytic recycling	The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.	got7fsn_ti	direct endocytic recycling													biological_process											owl:Class	
GO:0050236	biolink:NamedThing	pyridoxine:NADP 4-dehydrogenase activity	Catalysis of the reaction: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal.	got7fsn_ti	pyridoxin dehydrogenase activity|pyridoxol dehydrogenase activity|pyridoxine dehydrogenase activity|pyridoxine:NADP 4-oxidoreductase activity|pyridoxal reductase activity|PL reductase activity											MetaCyc:PYRIDOXINE-4-DEHYDROGENASE-RXN|RHEA:16129|KEGG_REACTION:R01708|EC:1.1.1.65		molecular_function											owl:Class	
GO:1990355	biolink:NamedThing	L-methionine salvage from methionine sulphoxide	The generation of L-methionine from methionine sulphoxide.	got7fsn_ti	methionine salvage from methionine sulphoxide						al	2014-04-02T12:55:01Z						biological_process											owl:Class	
GO:0047385	biolink:NamedThing	[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity	Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)].	got7fsn_ti	branched-chain 2-keto acid dehydrogenase phosphatase activity|branched-chain oxo-acid dehydrogenase phosphatase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphatase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity|branched-chain alpha-keto acid dehydrogenase phosphatase											EC:3.1.3.52|MetaCyc:3.1.3.52-RXN		molecular_function											owl:Class	
GO:0071606	biolink:NamedThing	chemokine (C-C motif) ligand 4 production	The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	MIP-1b production|CCL4 production|macrophage inflammatory protein production						mah	2010-02-05T04:16:42Z						biological_process											owl:Class	
GO:0042612	biolink:NamedThing	MHC class I protein complex	A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.	got7fsn_ti					See also the cellular component term 'MHC class I peptide loading complex ; GO:0042824'.									cellular_component											owl:Class	
GO:0097515	biolink:NamedThing	asexual spore wall	A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species.	got7fsn_ti							pr	2013-10-16T15:11:21Z						cellular_component											owl:Class	
GO:0034216	biolink:NamedThing	high-affinity thiamine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high-affinity thiamin:hydrogen symporter activity|high affinity thiamin:hydrogen symporter activity|high-affinity thiamine:hydrogen symporter activity|high-affinity thiamin:proton symporter activity													molecular_function											owl:Class	
GO:0034215	biolink:NamedThing	thiamine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in).	got7fsn_ti	thiamin:proton symporter activity|thiamine:hydrogen symporter activity|thiamin:hydrogen symporter activity													molecular_function											owl:Class	
GO:0050471	biolink:NamedThing	uracilylalanine synthase activity	Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.	got7fsn_ti	3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity|O3-acetyl-L-serine acetate-lyase (adding uracil)|O(3)-acetyl-L-serine acetate-lyase (adding uracil) activity|Willardiine synthase activity|isowillardiine synthase activity|O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity											RHEA:11496|EC:2.5.1.53|MetaCyc:URACILYLALANINE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0018425	biolink:NamedThing	O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process	The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds.	got7fsn_ti	O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthesis|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine formation|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine anabolism|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine synthesis											RESID:AA0296		biological_process											owl:Class	
GO:0102884	biolink:NamedThing	alpha-zingiberene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> zingiberene + diphosphoric acid.	got7fsn_ti												RHEA:28643|MetaCyc:RXN-8425|EC:4.2.3.65		molecular_function											owl:Class	
GO:0070353	biolink:NamedThing	GATA1-TAL1-TCF3-Lmo2 complex	A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0019281	biolink:NamedThing	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine.	got7fsn_ti	L-methionine synthesis from homoserine via O-succinyl-L-homoserine and cystathionine|methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine formation from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-succinyl-L-homoserine and cystathionine											MetaCyc:MET-SAM-PWY		biological_process											owl:Class	
GO:0007614	biolink:NamedThing	short-term memory	The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.	got7fsn_ti												Wikipedia:Short-term_memory		biological_process											owl:Class	
GO:1990687	biolink:NamedThing	endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.	got7fsn_ti	ER-derived vesicle fusion with ER-Golgi intermediate compartment membrane|ER-derived vesicle fusion with ERGIC membrane						bhm	2015-03-12T09:31:45Z						biological_process											owl:Class	
GO:0071958	biolink:NamedThing	new mitotic spindle pole body	The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize.	got7fsn_ti	new SPB						mah	2011-06-01T02:34:34Z						cellular_component											owl:Class	
GO:0001162	biolink:NamedThing	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	Binding to an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.	got7fsn_ti					To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2011-01-28T03:46:19Z						molecular_function											owl:Class	
GO:0043728	biolink:NamedThing	2-keto-4-methylthiobutyrate aminotransferase activity	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine.	got7fsn_ti												EC:4.1.1.-		molecular_function											owl:Class	
GO:0008111	biolink:NamedThing	alpha-methylacyl-CoA racemase activity	Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA.	got7fsn_ti	2-methylacyl-CoA 2-epimerase activity											Reactome:R-HSA-193452|Reactome:R-HSA-193736|Reactome:R-HSA-193763|EC:5.1.99.4|Reactome:R-HSA-389897|Reactome:R-HSA-192056|RHEA:12657|MetaCyc:5.1.99.4-RXN		molecular_function											owl:Class	
GO:0050010	biolink:NamedThing	isovitexin beta-glucosyltransferase activity	Catalysis of the reaction: isovitexin + UDP-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP.	got7fsn_ti	isovitexin b-glucosyltransferase activity|uridine diphosphoglucose-isovitexin 2''-glucosyltransferase activity|UDP-glucose:isovitexin 2''-O-beta-D-glucosyltransferase activity|UDPglucose:isovitexin 2''-O-beta-D-glucosyltransferase activity											KEGG_REACTION:R03686|RHEA:19529|MetaCyc:ISOVITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.106		molecular_function											owl:Class	
GO:0002318	biolink:NamedThing	myeloid progenitor cell differentiation	The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.	got7fsn_ti														biological_process											owl:Class	
GO:0018574	biolink:NamedThing	2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity	Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate.	got7fsn_ti												UM-BBD_enzymeID:e0422|EC:1.13.11.-		molecular_function											owl:Class	
GO:0044656	biolink:NamedThing	regulation of post-lysosomal vacuole size	Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.	got7fsn_ti	regulation of post-lysosome size						jl	2012-07-26T04:30:56Z						biological_process											owl:Class	
GO:0102396	biolink:NamedThing	9-cis-10'-apo-beta-carotenal cleavage oxygenase activity	Catalysis of the reaction: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal.	got7fsn_ti												RHEA:34403|EC:1.13.11.69|MetaCyc:RXN-13643		molecular_function											owl:Class	
GO:0140464	biolink:NamedThing	silent mating-type cassette heterochromatin organization	The organization of chromatin into heterochromatin at a silent mating-type cassette locus.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19396					pg	2020-05-13T05:13:24Z						biological_process											owl:Class	
GO:0150062	biolink:NamedThing	complement-mediated synapse pruning	Synaptic pruning mediated by complement system signalling.	got7fsn_ti	synapse elimination|synapse clearance|synapse disassembly|synapse removal|complement-dependent synapse pruning						bc	2018-07-16T17:44:59Z						biological_process											owl:Class	
GO:0098883	biolink:NamedThing	synapse pruning	A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.	got7fsn_ti	synapse clearance|synapse disassembly|synapse removal|synapse elimination													biological_process											owl:Class	
GO:0052846	biolink:NamedThing	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity	Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+.	got7fsn_ti							ai	2011-12-05T11:02:23Z				MetaCyc:RXN-10965		molecular_function											owl:Class	
GO:0033299	biolink:NamedThing	secretion of lysosomal enzymes	The controlled release of lysosomal enzymes by a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0102725	biolink:NamedThing	24-methyldesmosterol reductase activity	Catalysis of the reaction: H+ + 24-methyldesmosterol + NADPH = campesterol + NADP.	got7fsn_ti												MetaCyc:RXN-708		molecular_function											owl:Class	
GO:0006978	biolink:NamedThing	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.	got7fsn_ti														biological_process											owl:Class	
GO:0047374	biolink:NamedThing	methylumbelliferyl-acetate deacetylase activity	Catalysis of the reaction: 4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate + H(+).	got7fsn_ti	4-methylumbelliferyl-acetate acylhydrolase activity|esterase D activity											KEGG_REACTION:R04141|RHEA:12208|EC:3.1.1.56|MetaCyc:3.1.1.56-RXN		molecular_function											owl:Class	
GO:0018575	biolink:NamedThing	chlorocatechol 1,2-dioxygenase activity	Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate.	got7fsn_ti												UM-BBD_reactionID:r0655|EC:1.13.11.-		molecular_function											owl:Class	
GO:0098621	biolink:NamedThing	phosphoseryl-selenocysteinyl-tRNA selenium transferase activity	Catalysis of the reaction: O-phosphoseryl-tRNA(Sec) + selenophosphoric acid + H2O => L-selenocysteinyl-tRNA(Sec) + 2 phosphoric acid.	got7fsn_ti												RHEA:25041|Reactome:R-HSA-2408555|EC:2.9.1.2		molecular_function											owl:Class	
GO:0140037	biolink:NamedThing	sumo-dependent protein binding	Binding to a protein upon sumoylation of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require sumoylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of sumoylation. It may be that the sumoylation causes a conformational change that allows binding of the protein to another region; this type of sumoylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-18T06:29:27Z						molecular_function											owl:Class	
GO:0102839	biolink:NamedThing	1-18:2-2-16:2-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.35|MetaCyc:RXN-8299		molecular_function											owl:Class	
GO:0021949	biolink:NamedThing	brainstem precerebellar neuron precursor migration	The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.	got7fsn_ti														biological_process											owl:Class	
GO:0016964	biolink:NamedThing	alpha-2 macroglobulin receptor activity	Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis.	got7fsn_ti														molecular_function											owl:Class	
GO:0102351	biolink:NamedThing	gamma-aminobutyrate transaminase (glyoxylate dependent) activity	Catalysis of the reaction: gamma-aminobutyric acid  + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine.	got7fsn_ti												EC:2.6.1.96|RHEA:32267|MetaCyc:RXN-13328		molecular_function											owl:Class	
GO:0070180	biolink:NamedThing	large ribosomal subunit rRNA binding	Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.	got7fsn_ti	25S rRNA binding|LSU rRNA binding													molecular_function											owl:Class	
GO:0002563	biolink:NamedThing	somatic diversification of immune receptors via alternate splicing	The process in which immune receptor genes are diversified through alternate splicing.	got7fsn_ti														biological_process											owl:Class	
GO:0010506	biolink:NamedThing	regulation of autophagy	Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	got7fsn_ti														biological_process											owl:Class	
GO:0106213	biolink:NamedThing	kinetochore disassembly involved in meiotic chromosome organization	The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I.	got7fsn_ti	kinetochore disassembly from spindle pole body involved in chromosome organization involved in meiotic cell cycle						hjd	2019-06-25T18:31:06Z						biological_process											owl:Class	
GO:0120043	biolink:NamedThing	stereocilium shaft	The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle.	got7fsn_ti							krc	2017-05-15T20:38:32Z						cellular_component											owl:Class	
GO:0097583	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p.	got7fsn_ti	Pmt1p-Pmt3p complex						pr	2014-03-02T18:16:29Z						cellular_component											owl:Class	
GO:0097455	biolink:NamedThing	spiny bracelet of Nageotte	Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin.	got7fsn_ti							pr	2012-12-19T13:02:33Z				NIF_Subcellular:sao937871668		cellular_component											owl:Class	
GO:0050192	biolink:NamedThing	phosphoglycerate phosphatase activity	Catalysis of the reaction: 2-phospho-D-glycerate + H(2)O = D-glycerate + phosphate.	got7fsn_ti	D-2-phosphoglycerate phosphatase activity|glycerophosphate phosphatase activity|D-glycerate-2-phosphate phosphohydrolase activity											RHEA:21156|KEGG_REACTION:R01748|MetaCyc:PHOSPHOGLYCERATE-PHOSPHATASE-RXN|EC:3.1.3.20		molecular_function											owl:Class	
GO:0000236	biolink:NamedThing	mitotic prometaphase	The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0031470	biolink:NamedThing	carboxysome	An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO(2). It augments the concentration of CO(2) in the vicinity of RuBisCO to increase the efficiency of CO(2) fixation under atmospheric conditions.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19743										Wikipedia:Carboxysome		cellular_component											owl:Class	
GO:0052850	biolink:NamedThing	NADPH-dependent dihydrocurcumin reductase activity	Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+.	got7fsn_ti	dihydrocurcumin reductase (NADPH) activity						ai	2011-12-05T11:04:23Z				MetaCyc:RXN0-6677		molecular_function											owl:Class	
GO:0090589	biolink:NamedThing	protein-phosphocysteine-trehalose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0070945	biolink:NamedThing	neutrophil-mediated killing of gram-negative bacterium	The directed killing of a gram-negative bacterium by a neutrophil.	got7fsn_ti	neutrophil mediated killing of gram-negative bacterium						mah	2009-10-01T01:59:12Z						biological_process											owl:Class	
GO:0043120	biolink:NamedThing	tumor necrosis factor binding	Binding to tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.	got7fsn_ti														molecular_function											owl:Class	
GO:0072685	biolink:NamedThing	Mre11 complex assembly	The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling.	got7fsn_ti	MRN complex assembly|MRX complex assembly|RMX complex assembly|Rad50 complex assembly|Rad50-Rad32-Nbs1 complex assembly|RAD50-MRE11-NBN complex assembly						mah	2011-05-12T02:52:06Z						biological_process											owl:Class	
GO:0052658	biolink:NamedThing	inositol-1,4,5-trisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.	got7fsn_ti	inosine triphosphatase activity|inositol triphosphate 5-phosphomonoesterase activity|inositol trisphosphate phosphomonoesterase activity|inositol polyphosphate-5-phosphatase activity|L-myo-inositol 1,4,5-trisphosphate-monoesterase activity|inositol 1,4,5-trisphosphate phosphatase activity|InsP3 5-phosphatase activity|type I inositol-polyphosphate phosphatase activity|inositol phosphate 5-phosphomonoesterase activity|D-myo-inositol(1,4,5)-trisphosphate 5-phosphatase activity|1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity|Ins(1,4,5)P3 5-phosphatase activity|myo-inositol-1,4,5-trisphosphate 5-phosphatase activity|D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity|InsP(3) 5-phosphatase activity|type II inositol polyphosphate 5-phosphatase activity|5PTase activity|D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity											Reactome:R-HSA-1855174|KEGG_REACTION:R03394|EC:3.1.3.56|RHEA:19797|Reactome:R-HSA-1855222|MetaCyc:3.1.3.56-RXN		molecular_function											owl:Class	
GO:0106332	biolink:NamedThing	ds/ssDNA junction-specific dsDNA endonuclease activity	Catalysis of the endonucleolytic cleavage of double-stranded DNA near a double-strand/single-strand DNA junction.	got7fsn_ti							hjd	2020-10-08T18:09:57Z						molecular_function											owl:Class	
GO:0036289	biolink:NamedThing	peptidyl-serine autophosphorylation	The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.	got7fsn_ti	serine autophosphorylation						bf	2012-07-18T10:24:32Z						biological_process											owl:Class	
GO:0043450	biolink:NamedThing	alkene biosynthetic process	The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.	got7fsn_ti	alkene formation|alkene anabolism|alkene biosynthesis|alkene synthesis													biological_process											owl:Class	
GO:0106361	biolink:NamedThing	protein-arginine rhamnosyltransferase activity	Catalysis of the reaction: dTDP-beta-L-rhamnose + L-arginyl-[protein] = dTDP + H(+) + N(omega)-(L-rhamnosyl)-L-arginyl-[protein].	got7fsn_ti							hjd	2021-02-05T15:39:52Z				RHEA:66692		molecular_function											owl:Class	
GO:0047549	biolink:NamedThing	2-nitrophenol 2-monooxygenase activity	Catalysis of the reaction: 2-nitrophenol + 2 H(+) + 2 NADPH + O(2) = catechol + H(2)O + 2 NADP(+) + nitrite.	got7fsn_ti	2-nitrophenol oxygenase activity|2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming)|nitrophenol oxygenase activity											MetaCyc:2-NITROPHENOL-2-MONOOXYGENASE-RXN|UM-BBD_reactionID:r1494|RHEA:19457|KEGG_REACTION:R00828|EC:1.14.13.31		molecular_function											owl:Class	
GO:0047632	biolink:NamedThing	agmatine deiminase activity	Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3.	got7fsn_ti	agmatine iminohydrolase activity|agmatine amidinohydrolase											RHEA:18037|EC:3.5.3.12|MetaCyc:AGMATINE-DEIMINASE-RXN		molecular_function											owl:Class	
GO:0044622	biolink:NamedThing	negative regulation of cell migration in other organism	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism.	got7fsn_ti							jl	2012-07-04T04:42:14Z						biological_process											owl:Class	
GO:0010644	biolink:NamedThing	cell communication by electrical coupling	The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti														biological_process											owl:Class	
GO:0050605	biolink:NamedThing	superoxide reductase activity	Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.	got7fsn_ti	rubredoxin:superoxide oxidoreductase activity|desulfoferrodoxin activity|neelaredoxin activity											RHEA:21324|EC:1.15.1.2|MetaCyc:1.15.1.2-RXN		molecular_function											owl:Class	
GO:0031850	biolink:NamedThing	delta-type opioid receptor binding	Binding to a delta-type opioid receptor.	got7fsn_ti	enkephalin receptor binding|delta-type opioid receptor ligand													molecular_function											owl:Class	
GO:0102047	biolink:NamedThing	indole-3-acetyl-glycine synthetase activity	Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) <=> H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10429		molecular_function											owl:Class	
GO:0018532	biolink:NamedThing	5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity	Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin.	got7fsn_ti	coenzyme F420-independent methylene-H4MPT dehydrogenase activity|coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity|F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity|F420-independent methylene-H4MPT dehydrogenase activity											EC:1.5.99.-|UM-BBD_reactionID:r0353		molecular_function											owl:Class	
GO:0046845	biolink:NamedThing	branched duct epithelial cell fate determination, open tracheal system	Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode.	got7fsn_ti	branch cell fate determination													biological_process											owl:Class	
GO:0018863	biolink:NamedThing	phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene.	got7fsn_ti												EC:3.3.2.-|UM-BBD_reactionID:r0496		molecular_function											owl:Class	
GO:0046541	biolink:NamedThing	saliva secretion	The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.	got7fsn_ti	salivation											Wikipedia:Salivation		biological_process											owl:Class	
GO:0032793	biolink:NamedThing	positive regulation of CREB transcription factor activity	Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.	got7fsn_ti	activation of CREB|activation of CREB transcription factor|CREB activator													biological_process											owl:Class	
GO:0106218	biolink:NamedThing	galactosaminogalactan biosynthetic process	The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN).	got7fsn_ti	galactosaminogalactan anabolism|GAG biosynthetic process|galactosaminogalactan synthesis|galactosaminogalactan formation|galactosaminogalactan biosynthesis						hjd	2019-08-05T14:46:56Z						biological_process											owl:Class	
GO:0102939	biolink:NamedThing	3-methoxy-5-hydroxytoluene O-methyltransferase activity	Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine  = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-9018		molecular_function											owl:Class	
GO:0018729	biolink:NamedThing	propionate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.	got7fsn_ti	propionyl CoA:acetate CoA transferase activity|propionyl-CoA transferase activity|propionate-CoA:lactoyl-CoA transferase activity|acetyl-CoA:propanoate CoA-transferase activity|propionate coenzyme A-transferase activity											EC:2.8.3.1|RHEA:23520|UM-BBD_reactionID:r0087|MetaCyc:PROPIONATE-COA-TRANSFERASE-RXN		molecular_function											owl:Class	
GO:0035872	biolink:NamedThing	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process.	got7fsn_ti	nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway|nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway|NOD-like receptor signaling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signal transduction|NLR signaling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway						bf	2011-05-26T03:30:36Z						biological_process											owl:Class	
GO:0006528	biolink:NamedThing	asparagine metabolic process	The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid.	got7fsn_ti	asparagine metabolism											MetaCyc:ASPARAGINESYN-PWY		biological_process											owl:Class	
GO:0060021	biolink:NamedThing	roof of mouth development	The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.	got7fsn_ti	palatum development													biological_process											owl:Class	
GO:0035160	biolink:NamedThing	maintenance of epithelial integrity, open tracheal system	Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.	got7fsn_ti	maintenance of tracheal epithelial integrity													biological_process											owl:Class	
GO:0031736	biolink:NamedThing	CCR11 chemokine receptor binding	Binding to a CCR11 chemokine receptor.	got7fsn_ti	CCR11 chemokine receptor ligand													molecular_function											owl:Class	
GO:0036357	biolink:NamedThing	2-phosphoglycerate kinase activity	Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP.	got7fsn_ti	2PGK activity				This reaction is the first step in the biosynthesis of cyclic 2,3-diphosphoglycerate (cDPG).		bf	2012-09-19T15:06:25Z				EC:2.7.2.-		molecular_function											owl:Class	
GO:1990116	biolink:NamedThing	ribosome-associated ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein.	got7fsn_ti	ribosome-associated degradation|RAD|ribosome-associated ubiquitin-dependent protein degradation|ribosome-associated ubiquitin-dependent protein breakdown|ribosome-associated ubiquitin-dependent protein catabolism						pr	2013-06-05T11:46:01Z						biological_process											owl:Class	
GO:0021673	biolink:NamedThing	rhombomere 7 formation	The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0003911	biolink:NamedThing	DNA ligase (NAD+) activity	Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m).	got7fsn_ti	deoxyribonucleic acid ligase|polynucleotide synthetase (nicotinamide adenine dinucleotide)|polynucleotide ligase|polynucleotide synthetase activity|DNA-joining enzyme|deoxyribonucleic ligase|DNA joinase activity|deoxyribonucleic-joining enzyme|deoxyribonucleate ligase|deoxyribonucleic joinase|DNA ligase (NAD)|polynucleotide ligase (NAD)|poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming, NMN-forming)|polynucleotide ligase (NAD(+)) activity|Polydeoxyribonucleotide synthase (NAD(+)) activity|polynucleotide ligase (nicotinamide adenine dinucleotide)|polydeoxyribonucleotide synthase (NAD+) activity|DNA repair enzyme activity|polydeoxyribonucleotide synthase (NAD)|polynucleotide ligase (NAD+) activity|deoxyribonucleic repair enzyme|deoxyribonucleic acid joinase											MetaCyc:DNA-LIGASE-NAD+-RXN|EC:6.5.1.2		molecular_function											owl:Class	
GO:0003700	biolink:NamedThing	DNA-binding transcription factor activity	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	got7fsn_ti	bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity|metal ion regulated sequence-specific DNA binding transcription factor activity|transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|DNA binding transcription factor activity|bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding|transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding|bacterial-type DNA binding transcription factor activity|gene-specific transcription factor activity|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity|bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding|nucleic acid binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription factor activity, metal ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity|transcription factor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|transcription factor activity|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity	https://github.com/geneontology/go-ontology/issues/16534|https://github.com/geneontology/go-ontology/issues/15704|https://github.com/geneontology/go-ontology/issues/20253			Usage guidance: Most DNA-binding transcription factors do not have enzymatic activity. The presence of specific DNA-binding domains known to be present in DNA-binding transcription factors (HOX, GATA etc) should be used to help decide whether a protein is a DNA binding transcription factor or a coregulator. If a protein has an enzymatic activity (for example, ubiquitin ligase, histone acetyl transferase) and no known DNA binding domain, consider annotating to GO:0003712 transcription coregulator activity. Special care should be taken with proteins containing zinc fingers, Myb/SANT and ARID domains, since only a subset of proteins containing these domains directly and selectively bind to regulatory DNA motifs in cis-regulatory regions.		krc	2010-10-21T04:37:54Z			GO:0001130|GO:0001204|GO:0001199|GO:0001071|GO:0000130|GO:0001131|GO:0001151			molecular_function											owl:Class	
GO:0014005	biolink:NamedThing	microglia development	The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti	microglial cell development													biological_process											owl:Class	
GO:0047606	biolink:NamedThing	hydroxynitrilase activity	Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone.	got7fsn_ti	acetone-cyanohydrin acetone-lyase activity|2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming)|alpha-hydroxynitrile lyase activity|oxynitrilase activity|(S)-acetone-cyanohydrin lyase activity|acetone-cyanohydrin lyase activity|hydroxynitrile lyase activity|2-hydroxyisobutyronitrile acetone-lyase activity|acetone-cyanhydrin lyase activity|acetone-cyanohydrin acetone-lyase (cyanide-forming)										GO:0046991	MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN|EC:4.1.2.47		molecular_function											owl:Class	
GO:0010280	biolink:NamedThing	UDP-L-rhamnose synthase activity	Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O.	got7fsn_ti	UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase-4-reductase activity											MetaCyc:RXN-5482		molecular_function											owl:Class	
GO:2001066	biolink:NamedThing	amylopectin binding	Binding to amylopectin.	got7fsn_ti							jl	2011-09-14T11:46:37Z						molecular_function											owl:Class	
GO:0003919	biolink:NamedThing	FMN adenylyltransferase activity	Catalysis of the reaction: ATP + FMN = diphosphate + FAD.	got7fsn_ti	FAD synthetase activity|ATP:FMN adenylyltransferase activity|riboflavin mononucleotide adenylyltransferase activity|adenosine triphosphate-riboflavin mononucleotide transadenylase activity|FAD diphosphorylase activity|adenosine triphosphate-riboflavine mononucleotide transadenylase activity|riboflavin adenine dinucleotide pyrophosphorylase activity|FAD pyrophosphorylase activity|flavin adenine dinucleotide synthetase activity|riboflavine adenine dinucleotide adenylyltransferase activity											RHEA:17237|KEGG_REACTION:R00161|Reactome:R-HSA-196929|MetaCyc:FADSYN-RXN|EC:2.7.7.2		molecular_function											owl:Class	
GO:0140036	biolink:NamedThing	ubiquitin-dependent protein binding	Binding to a protein upon ubiquitination of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require ubiquitination of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of ubiquitination. It may be that the ubiquitination causes a conformational change that allows binding of the protein to another region; this type of ubiquitination-dependent protein binding is valid for annotation to this term.		pg	2017-05-18T06:29:14Z						molecular_function											owl:Class	
GO:0020025	biolink:NamedThing	subpellicular microtubule	Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid.	got7fsn_ti														cellular_component											owl:Class	
GO:0002096	biolink:NamedThing	polkadots	A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.	got7fsn_ti					Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots.									cellular_component											owl:Class	
GO:0018118	biolink:NamedThing	peptidyl-L-cysteine glutathione disulfide biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine by covalent addition of glutathione to form peptidyl-L-cysteine glutathione disulfide.	got7fsn_ti	peptidyl-L-cysteine glutathione disulfide synthesis from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide anabolism from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulphide biosynthesis from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulphide biosynthetic process from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide formation from peptidyl-cysteine											RESID:AA0229		biological_process											owl:Class	
GO:0070016	biolink:NamedThing	armadillo repeat domain binding	Binding to an armadillo repeat domain, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.	got7fsn_ti	armadillo repeat binding|Arm repeat domain binding|armadillo domain binding													molecular_function											owl:Class	
GO:0030165	biolink:NamedThing	PDZ domain binding	Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins.	got7fsn_ti	DHR-domain binding|GLGF-domain binding													molecular_function											owl:Class	
GO:0021813	biolink:NamedThing	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration	The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex.	got7fsn_ti	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:1990358	biolink:NamedThing	xylanosome	A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose.	got7fsn_ti	xylanolytic complex						tt	2014-04-05T18:08:54Z						cellular_component											owl:Class	
GO:0019416	biolink:NamedThing	polythionate oxidation	The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor.	got7fsn_ti												MetaCyc:THIOSULFOX-PWY		biological_process											owl:Class	
GO:0032426	biolink:NamedThing	stereocilium tip	A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation.	got7fsn_ti														cellular_component											owl:Class	
GO:0032051	biolink:NamedThing	clathrin light chain binding	Binding to a clathrin light chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0008687	biolink:NamedThing	3,4-dihydroxyphenylacetate 2,3-dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O(2) = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H(+).	got7fsn_ti	3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing)|3,4-dihydroxyphenylacetic acid 2,3-dioxygenase activity|homoprotocatechuate 2,3-dioxygenase activity|HPC dioxygenase activity											UM-BBD_reactionID:r0364|KEGG_REACTION:R03303|RHEA:15633|MetaCyc:1.13.11.15-RXN|EC:1.13.11.15		molecular_function											owl:Class	
GO:0085044	biolink:NamedThing	disassembly by symbiont of host cuticle	The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism of host cuticle|degradation of host cuticle						jl	2010-07-27T01:08:15Z						biological_process											owl:Class	
GO:0030451	biolink:NamedThing	regulation of complement activation, alternative pathway	Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation.	got7fsn_ti	regulation of complement cascade, alternative pathway													biological_process											owl:Class	
GO:0018862	biolink:NamedThing	phenylphosphate carboxylase activity	Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate.	got7fsn_ti												UM-BBD_reactionID:r0157|EC:6.4.1.-|MetaCyc:PHENYLPCARB-RXN		molecular_function											owl:Class	
GO:0033786	biolink:NamedThing	heptose-1-phosphate adenylyltransferase activity	Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose.	got7fsn_ti	D-beta-D-heptose 1-phosphate adenylyltransferase activity|heptose 1-phosphate adenyltransferase activity											RHEA:27465|MetaCyc:RXN0-4342		molecular_function											owl:Class	
GO:0031800	biolink:NamedThing	type 3 metabotropic glutamate receptor binding	Binding to a type 3 metabotropic glutamate receptor.	got7fsn_ti	type 3 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0045794	biolink:NamedThing	negative regulation of cell volume	Any process that decreases cell volume.	got7fsn_ti	cell regulatory volume decrease|RVD													biological_process											owl:Class	
GO:0035181	biolink:NamedThing	larval burrowing behavior	Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.	got7fsn_ti	larval burrowing behaviour													biological_process											owl:Class	
GO:0060509	biolink:NamedThing	type I pneumocyte differentiation	The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.	got7fsn_ti	small alveolar cell differentiation|squamous alveolar cell differentiation|membranous pneumocyte differentiation													biological_process											owl:Class	
GO:0036237	biolink:NamedThing	acyl-glucuronidase activity	Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate.	got7fsn_ti	acyl-glucuronide deglucuronidation activity						bf	2012-05-18T04:32:25Z						molecular_function											owl:Class	
GO:0043914	biolink:NamedThing	NADPH:sulfur oxidoreductase activity	Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+.	got7fsn_ti	NAD(P)H sulfur oxidoreductase activity|CoA-dependent NAD(P)H sulfur oxidoreductase activity|NSR|NADPH:sulphur oxidoreductase activity|coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity|NAD(P)H sulphur oxidoreductase activity|NAD(P)H elemental sulfur oxidoreductase activity|NAD(P)H:sulfur oxidoreductase activity											EC:1.8.1.18		molecular_function											owl:Class	
GO:0098978	biolink:NamedThing	glutamatergic synapse	A synapse that uses glutamate as a neurotransmitter.	got7fsn_ti														cellular_component											owl:Class	
GO:0030670	biolink:NamedThing	phagocytic vesicle membrane	The lipid bilayer surrounding a phagocytic vesicle.	got7fsn_ti	phagosome membrane													cellular_component											owl:Class	
GO:1900814	biolink:NamedThing	monodictyphenone catabolic process	The chemical reactions and pathways resulting in the breakdown of monodictyphenone.	got7fsn_ti	monodictyphenone catabolism|monodictyphenone degradation|monodictyphenone breakdown						di	2012-06-04T10:11:27Z						biological_process											owl:Class	
GO:0019896	biolink:NamedThing	axonal transport of mitochondrion	The directed movement of mitochondria along microtubules in nerve cell axons.	got7fsn_ti	axon transport of mitochondria													biological_process											owl:Class	
GO:0098930	biolink:NamedThing	axonal transport	The directed movement of organelles or molecules along microtubules in axons.	got7fsn_ti	axoplasmic transport|axon cargo transport											Wikipedia:Axoplasmic_transport		biological_process											owl:Class	
GO:0046567	biolink:NamedThing	aphidicolan-16 beta-ol synthase activity	Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate.	got7fsn_ti	9-alpha-copalyl-diphosphate diphosphate-lyase (aphidicolan-16-beta-ol-forming)											RHEA:26213|MetaCyc:RXN-10631|EC:4.2.3.42|KEGG_REACTION:R06313		molecular_function											owl:Class	
GO:0009624	biolink:NamedThing	response to nematode	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.	got7fsn_ti	response to nematodes													biological_process											owl:Class	
GO:0047367	biolink:NamedThing	quercetin-3,3'-bissulfate 7-sulfotransferase activity	Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.	got7fsn_ti	quercetin-3,3'-bissulphate 7-sulphotransferase activity|flavonol 7-sulfotransferase activity|PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase activity|7-sulfotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase activity											EC:2.8.2.28|MetaCyc:2.8.2.28-RXN|RHEA:21860		molecular_function											owl:Class	
GO:0071800	biolink:NamedThing	podosome assembly	The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.	got7fsn_ti							mah	2010-09-03T11:00:45Z						biological_process											owl:Class	
GO:0047258	biolink:NamedThing	sphingosine beta-galactosyltransferase activity	Catalysis of the reaction: sphingosine + UDP-D-galactose = H(+) + psychosine + UDP.	got7fsn_ti	uridine diphosphogalactose-sphingosine beta-galactosyltransferase activity|galactosyl-sphingosine transferase activity|psychosine-UDP galactosyltransferase activity|UDPgalactose:sphingosine O-galactosyl transferase activity|UDP-galactose:sphingosine 1-beta-galactotransferase activity|psychosine-uridine diphosphate galactosyltransferase activity|UDPgalactose:sphingosine 1-beta-galactotransferase activity											MetaCyc:2.4.1.23-RXN|EC:2.4.1.23|KEGG_REACTION:R01928|RHEA:19485		molecular_function											owl:Class	
GO:0070478	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay	The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.	got7fsn_ti	3'-5' NMD|nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay|nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay|3'-5' nonsense-mediated decay|3'-5' nonsense-mediated mRNA decay|nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay													biological_process											owl:Class	
GO:0034427	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.	got7fsn_ti	3'-5' exonucleolytic nuclear-transcribed mRNA catabolic process													biological_process											owl:Class	
GO:0050604	biolink:NamedThing	taxadiene 5-alpha-hydroxylase activity	Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol.	got7fsn_ti	taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating)|taxadiene 5a-hydroxylase activity|taxadiene 5alpha-hydroxylase activity											MetaCyc:1.14.99.37-RXN|KEGG_REACTION:R06306|RHEA:14049|EC:1.14.14.176		molecular_function											owl:Class	
GO:0052635	biolink:NamedThing	C-20 gibberellin 2-beta-dioxygenase activity	Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons.	got7fsn_ti	C-20 gibberellin 2-beta-hydroxylase activity|C-20 GA 2-oxidase activity|C-20 gibberellin 2beta-dioxygenase activity|C-20 gibberellin 2beta-hydroxylase activity|(C-20 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|C-20 gibberellin 2-oxidase activity|C(20) gibberellin 2-oxidase activity													molecular_function											owl:Class	
GO:0050367	biolink:NamedThing	tyrosine-arginine ligase activity	Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H(+).	got7fsn_ti	L-tyrosine:L-arginine ligase (AMP-forming)|kyotorphin synthase activity|kyotorphin-synthesizing enzyme activity|tyrosyl-arginine synthase activity|kyotorphin synthetase activity											KEGG_REACTION:R00735|RHEA:15345|EC:6.3.2.24|MetaCyc:TYROSINE--ARGININE-LIGASE-RXN		molecular_function											owl:Class	
GO:0035814	biolink:NamedThing	negative regulation of renal sodium excretion	Any process that decreases the amount of sodium excreted in urine over a unit of time.	got7fsn_ti					The amount of sodium excreted in urine over a unit of time can be decreased by decreasing the volume of urine produced (antidiuresis) and/or by decreasing the concentration of sodium in the urine.		bf	2011-04-20T01:27:39Z						biological_process											owl:Class	
GO:0032980	biolink:NamedThing	keratinocyte activation	A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.	got7fsn_ti														biological_process											owl:Class	
GO:0000973	biolink:NamedThing	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery	The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed.	got7fsn_ti							krc	2009-09-10T12:28:04Z						biological_process											owl:Class	
GO:0000972	biolink:NamedThing	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.	got7fsn_ti							krc	2009-09-10T12:25:11Z						biological_process											owl:Class	
GO:0102690	biolink:NamedThing	isopentenyladenine UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine = H+ + 9-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP.	got7fsn_ti												MetaCyc:RXN-4728		molecular_function											owl:Class	
GO:0043750	biolink:NamedThing	phosphatidylinositol alpha-mannosyltransferase activity	Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol.	got7fsn_ti	guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase activity|GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase activity|GDP mannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity|GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity|phosphatidyl-myo-inositol alpha-mannosyltransferase activity|GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase activity											RHEA:47368|EC:2.4.1.345|MetaCyc:2.4.1.57-RXN		molecular_function											owl:Class	
GO:0033924	biolink:NamedThing	dextran 1,6-alpha-isomaltotriosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.	got7fsn_ti	1,6-alpha-D-glucan isomaltotriohydrolase activity|exo-isomaltotriohydrolase activity											MetaCyc:3.2.1.95-RXN|EC:3.2.1.95		molecular_function											owl:Class	
GO:0097159	biolink:NamedThing	organic cyclic compound binding	Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.	got7fsn_ti							pr	2011-09-23T02:31:01Z						molecular_function											owl:Class	
GO:0002951	biolink:NamedThing	leukotriene-C(4) hydrolase	Catalysis of the reaction Leukotriene C(4) + H(2)O= leukotriene D(4) + L-glutamate.	got7fsn_ti					The mouse enzyme is specific for leukotriene C(4), while the human enzyme also has considerable activity toward glutathione and oxidized glutathione (cf. EC:3.4.19.13). PMID:9774450 cites that the mouse form of this enzyme failed to measure activity towards glutathione.									molecular_function											owl:Class	
GO:0060202	biolink:NamedThing	clathrin-sculpted acetylcholine transport vesicle lumen	The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle.	got7fsn_ti	clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle lumen|clathrin sculpted acetylcholine transport vesicle lumen													cellular_component											owl:Class	
GO:0120305	biolink:NamedThing	regulation of pigmentation	Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20524					krc	2021-02-09T19:37:35Z						biological_process											owl:Class	
GO:0031889	biolink:NamedThing	urotensin receptor binding	Binding to a urotensin receptor.	got7fsn_ti	urotensin receptor ligand													molecular_function											owl:Class	
GO:0043642	biolink:NamedThing	novobiocin biosynthetic process	The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.	got7fsn_ti												Wikipedia:Novobiocin		biological_process											owl:Class	
GO:0099524	biolink:NamedThing	postsynaptic cytosol	The region of the cytosol consisting of all cytosol that is part of the postsynapse.	got7fsn_ti														cellular_component											owl:Class	
GO:0004737	biolink:NamedThing	pyruvate decarboxylase activity	Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.	got7fsn_ti	alpha-carboxylase activity|2-oxo-acid carboxy-lyase activity|pyruvic decarboxylase activity|2-oxo-acid carboxy-lyase (aldehyde-forming)|alpha-ketoacid carboxylase activity											MetaCyc:PYRUVATE-DECARBOXYLASE-RXN|RHEA:11628|EC:4.1.1.1		molecular_function											owl:Class	
GO:0047997	biolink:NamedThing	hydroxypyruvate decarboxylase activity	Catalysis of the reaction: 3-hydroxypyruvate + H(+) = CO(2) + glycolaldehyde.	got7fsn_ti	hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)|hydroxypyruvate carboxy-lyase activity											KEGG_REACTION:R01393|MetaCyc:HYDROXYPYRUVATE-DECARBOXYLASE-RXN|RHEA:20561|EC:4.1.1.40		molecular_function											owl:Class	
GO:0010402	biolink:NamedThing	pectic arabinan metabolic process	The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I.	got7fsn_ti	pectic arabinan metabolism													biological_process											owl:Class	
GO:0047515	biolink:NamedThing	1,3-beta-oligoglucan phosphorylase activity	Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.	got7fsn_ti	beta-1,3-oligoglucan phosphorylase activity|beta-1,3-oligoglucan:orthophosphate glucosyltransferase II activity|1,3-beta-D-oligoglucan:phosphate alpha-D-glucosyltransferase activity											EC:2.4.1.30|MetaCyc:13-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN|RHEA:16041		molecular_function											owl:Class	
GO:0071621	biolink:NamedThing	granulocyte chemotaxis	The movement of a granulocyte in response to an external stimulus.	got7fsn_ti							mah	2010-02-09T04:08:17Z						biological_process											owl:Class	
GO:0070090	biolink:NamedThing	metaphase plate	The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.	got7fsn_ti														cellular_component											owl:Class	
GO:0039615	biolink:NamedThing	T=1 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres.	got7fsn_ti							bf	2012-07-18T01:46:17Z				VZ:1057		cellular_component											owl:Class	
GO:0047222	biolink:NamedThing	mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP.	got7fsn_ti	uridine diphosphoacetylglucosamine mannoside alpha1->2-alphacetylglucosaminyltransferase activity|alpha-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:mannotetraose alpha-N-acetyl-D-glucosaminyltransferase activity											MetaCyc:2.4.1.138-RXN|RHEA:13705|EC:2.4.1.138		molecular_function											owl:Class	
GO:0047693	biolink:NamedThing	ATP diphosphatase activity	Catalysis of the reaction: ATP + H2O = AMP + diphosphate.	got7fsn_ti	ATP diphosphohydrolase|ATP diphosphohydrolase (diphosphate-forming)|ATP pyrophosphatase activity|adenosine triphosphate pyrophosphatase activity											EC:3.6.1.8|MetaCyc:ATP-PYROPHOSPHATASE-RXN|RHEA:14245		molecular_function											owl:Class	
GO:0047303	biolink:NamedThing	glycine-oxaloacetate transaminase activity	Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate.	got7fsn_ti	glycine-oxaloacetate aminotransferase activity|glycine-oxalacetate aminotransferase activity|glycine:oxaloacetate aminotransferase activity|glycine--oxaloacetate aminotransferase activity											EC:2.6.1.35|KEGG_REACTION:R00373|MetaCyc:2.6.1.35-RXN|RHEA:17141		molecular_function											owl:Class	
GO:0038022	biolink:NamedThing	G protein-coupled olfactory receptor activity	Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	G-protein coupled olfactory receptor activity|G-protein coupled odorant receptor activity|olfactory receptor activity, G-protein coupled|odorant receptor activity, G-protein coupled						bf	2011-07-01T11:23:51Z						molecular_function											owl:Class	
GO:0071101	biolink:NamedThing	alpha4-beta1 integrin-JAM2 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.	got7fsn_ti	ITGA4-ITGB1-JAM2 complex						mah	2009-11-06T04:52:59Z						cellular_component											owl:Class	
GO:0038066	biolink:NamedThing	p38MAPK cascade	An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.	got7fsn_ti	p38 MAPK cascade|p38 cascade						bf	2012-01-25T11:51:24Z						biological_process											owl:Class	
GO:0071980	biolink:NamedThing	cell surface adhesin-mediated gliding motility	Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.	got7fsn_ti							mah	2010-10-21T03:03:44Z						biological_process											owl:Class	
GO:0102996	biolink:NamedThing	beta,beta digalactosyldiacylglycerol galactosyltransferase activity	Catalysis of the reaction: a 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + a beta,beta digalactosyldiacylglycerol <=> a trigalactosyldiacylglycerol + a 1,2-diacyl-sn-glycerol.	got7fsn_ti												MetaCyc:RXN-9721|EC:2.4.1.184		molecular_function											owl:Class	
GO:0047165	biolink:NamedThing	flavonol-3-O-beta-glucoside O-malonyltransferase activity	Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA.	got7fsn_ti	MAT-3|malonyl-coenzyme A:flavonol-3-O-glucoside malonyltransferase activity|flavonol 3-O-glucoside malonyltransferase activity|malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase activity											RHEA:20085|EC:2.3.1.116|MetaCyc:2.3.1.116-RXN		molecular_function											owl:Class	
GO:0035177	biolink:NamedThing	larval foraging behavior	The movement of a larva through a feeding substrate whilst feeding on food.	got7fsn_ti	larval foraging behaviour													biological_process											owl:Class	
GO:0071514	biolink:NamedThing	genetic imprinting	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.	got7fsn_ti	DNA imprinting						mah	2010-01-06T11:56:31Z						biological_process											owl:Class	
GO:0003937	biolink:NamedThing	IMP cyclohydrolase activity	Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide.	got7fsn_ti	IMP 1,2-hydrolase (decyclizing)|inosinate cyclohydrolase activity|IMP synthetase activity|inosinicase activity											EC:3.5.4.10|RHEA:18445|Reactome:R-HSA-73797|MetaCyc:IMPCYCLOHYDROLASE-RXN		molecular_function											owl:Class	
GO:0102345	biolink:NamedThing	3-hydroxy-lignoceroyl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA(4-) <=> trans-2-tetracosenoyl-CoA + H2O.	got7fsn_ti												MetaCyc:RXN-13304|EC:4.2.1.134		molecular_function											owl:Class	
GO:0046031	biolink:NamedThing	ADP metabolic process	The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate.	got7fsn_ti	ADP metabolism													biological_process											owl:Class	
GO:0046202	biolink:NamedThing	cyanide biosynthetic process	The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.	got7fsn_ti	cyanide biosynthesis|cyanide anabolism|cyanide synthesis|cyanide formation													biological_process											owl:Class	
GO:0051876	biolink:NamedThing	pigment granule dispersal	The directed movement of pigment granules within a cell towards the cell periphery.	got7fsn_ti														biological_process											owl:Class	
GO:0047970	biolink:NamedThing	guanidinoacetase activity	Catalysis of the reaction: guanidinoacetate + H(2)O = glycine + urea.	got7fsn_ti	glycocyaminase activity|guanidinoacetate amidinohydrolase activity											MetaCyc:GUANIDINOACETASE-RXN|KEGG_REACTION:R00775|RHEA:23268|EC:3.5.3.2		molecular_function											owl:Class	
GO:0047504	biolink:NamedThing	(-)-menthol dehydrogenase activity	Catalysis of the reaction: (-)-menthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH.	got7fsn_ti	(-)-menthol:NADP+ oxidoreductase activity|monoterpenoid dehydrogenase activity											RHEA:13917|EC:1.1.1.207|KEGG_REACTION:R02177|MetaCyc:--MENTHOL-DEHYDROGENASE-RXN|UM-BBD_reactionID:r1182		molecular_function											owl:Class	
GO:0045849	biolink:NamedThing	negative regulation of nurse cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process.	got7fsn_ti	down-regulation of nurse cell apoptosis|down regulation of nurse cell apoptosis|inhibition of nurse cell apoptosis|downregulation of nurse cell apoptosis|negative regulation of nurse cell apoptosis													biological_process											owl:Class	
GO:0047652	biolink:NamedThing	allantoate deiminase activity	Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine.	got7fsn_ti	allantoate amidinohydrolase (decarboxylating)|allantoate amidohydrolase activity											MetaCyc:ALLANTOATE-DEIMINASE-RXN|EC:3.5.3.9|RHEA:27485		molecular_function											owl:Class	
GO:0097694	biolink:NamedThing	establishment of RNA localization to telomere	The directed movement of RNA to a specific location in the telomeric region of a chromosome.	got7fsn_ti	establishment of RNA localisation to telomere						pr	2015-12-22T09:33:43Z						biological_process											owl:Class	
GO:0016322	biolink:NamedThing	neuron remodeling	The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.	got7fsn_ti	axon pruning|neuronal remodeling													biological_process											owl:Class	
GO:0070462	biolink:NamedThing	plus-end specific microtubule depolymerization	The removal of tubulin heterodimers from the plus end of a microtubule.	got7fsn_ti														biological_process											owl:Class	
GO:0106006	biolink:NamedThing	cytoskeletal protein-membrane anchor activity	The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a plasma membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific cortical membrane location.	got7fsn_ti	BAR domain adaptor|cytoskeletal protein-membrane adaptor activity|cytoskeletal protein membrane tether activity|microtubule cortical anchor activity|cytoskeletal protein membrane anchor activity|membrane-cytoskeletal protein tether activity|F-BAR domain adaptor|cytoskeletal protein membrane adaptor|membrane-cytoskeletal protein anchor activity	https://github.com/geneontology/go-ontology/issues/18281|https://github.com/geneontology/go-ontology/issues/17668|https://github.com/geneontology/go-ontology/issues/19119					hjd	2017-04-14T15:11:13Z			GO:0140362			molecular_function											owl:Class	
GO:1990339	biolink:NamedThing	laminin-522 complex	A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains.	got7fsn_ti	laminin-522						bhm	2014-03-20T23:41:32Z						cellular_component											owl:Class	
GO:0033719	biolink:NamedThing	2-oxo-acid reductase activity	Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.	got7fsn_ti	2-oxoacid reductase activity|(2R)-hydroxy-carboxylate:acceptor oxidoreductase activity|HVOR|(2R)-hydroxycarboxylate-viologen-oxidoreductase activity											EC:1.1.99.30|MetaCyc:1.1.99.30-RXN|RHEA:23664		molecular_function											owl:Class	
GO:0035979	biolink:NamedThing	histone kinase activity (H2A-S139 specific)	Catalysis of the transfer of a phosphate group to the serine-139 residue of the C-terminal tail of histone H2A.	got7fsn_ti	histone kinase activity (H2A.x-S139 specific)				Residue 1 of histone H2A is taken as the first residue following removal of the initiating Methionine (Met).		bf	2011-08-22T01:13:34Z						molecular_function											owl:Class	
GO:0140586	biolink:NamedThing	promoter-terminator loop anchoring activity	Bridging together a cis-regulatory element and a terminator DNA sequences on the chromatin, holding two loop anchors together, maintaining a chromatin loop.	got7fsn_ti	terminator-promoter loop anchoring activity	https://github.com/geneontology/go-ontology/issues/20204			Note that GO does not separately defines enhancers, since this concept is very close to that of cis-regulatory elements. However the literature refers to 'promoter-enhancer loops' to describe loops that bring together cis-regulatory elements. Note also that while SO defines 'promoter' as the core promoter, here it is used to mean a cis-regulatory element.		pg	2021-02-04T14:51:44Z						molecular_function											owl:Class	
GO:0080057	biolink:NamedThing	sepal vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the sepal of vascular plants.	got7fsn_ti							dhl	2009-04-13T02:26:19Z						biological_process											owl:Class	
GO:0072672	biolink:NamedThing	neutrophil extravasation	The migration of a neutrophil from the blood vessels into the surrounding tissue.	got7fsn_ti							mah	2011-02-21T03:03:52Z						biological_process											owl:Class	
GO:0048763	biolink:NamedThing	calcium-induced calcium release activity	Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration.	got7fsn_ti														molecular_function											owl:Class	
GO:0042278	biolink:NamedThing	purine nucleoside metabolic process	The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	got7fsn_ti	purine metabolic process|purine metabolism|purine nucleoside metabolism													biological_process											owl:Class	
GO:0060109	biolink:NamedThing	medial layer of collagen and cuticulin-based cuticle extracellular matrix	The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals.	got7fsn_ti	medial layer struts													cellular_component											owl:Class	
GO:0102097	biolink:NamedThing	(22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity	Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + O2 + NADPH + H+ <=> 3-dehydro-6-deoxoteasterone + NADP + H2O.	got7fsn_ti												EC:1.14.14.147|RHEA:27325|MetaCyc:RXN-11101		molecular_function											owl:Class	
GO:0016817	biolink:NamedThing	hydrolase activity, acting on acid anhydrides	Catalysis of the hydrolysis of any acid anhydride.	got7fsn_ti	hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement											EC:3.6.-.-		molecular_function											owl:Class	
GO:0047525	biolink:NamedThing	2'-hydroxydaidzein reductase activity	Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+.	got7fsn_ti	2'-hydroxydihydrodaidzein:NADP(+) 2'-oxidoreductase activity|2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase activity|HDR activity|2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase activity|NADPH:2'-hydroxydaidzein oxidoreductase activity											EC:1.3.1.51|MetaCyc:RXN-4502|RHEA:17145		molecular_function											owl:Class	
GO:0030156	biolink:NamedThing	benzodiazepine receptor binding	Binding to a peripheral benzodiazepine receptor (PBR).	got7fsn_ti	benzodiazepine receptor ligand|diazepam binding inhibitor activity													molecular_function											owl:Class	
GO:0047803	biolink:NamedThing	cysteine lyase activity	Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide.	got7fsn_ti	L-cysteine hydrogen-sulfide-lyase (adding sulfite)|L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming)|cysteine (sulfite) lyase activity											EC:4.4.1.10|RHEA:20916|MetaCyc:CYSTEINE-LYASE-RXN		molecular_function											owl:Class	
GO:0102121	biolink:NamedThing	ceramidase activity	Catalysis of the reaction: H2O + a ceramide = a sphingoid base + a fatty acid.	got7fsn_ti												EC:3.5.1.23|MetaCyc:RXN-11375		molecular_function											owl:Class	
GO:0047294	biolink:NamedThing	phosphoglycerol geranylgeranyltransferase activity	Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.	got7fsn_ti	geranylgeranyl-transferase activity|geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity|glycerol phosphate geranylgeranyltransferase activity											MetaCyc:2.5.1.41-RXN|EC:2.5.1.41|RHEA:23404|KEGG_REACTION:R04158		molecular_function											owl:Class	
GO:0031997	biolink:NamedThing	N-terminal myristoylation domain binding	Binding to the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin.	got7fsn_ti														molecular_function											owl:Class	
GO:0039646	biolink:NamedThing	modulation by virus of host G0/G1 transition checkpoint	Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint.	got7fsn_ti	G0/G1 host cell cycle checkpoint dysregulation by virus						bf	2012-10-09T15:11:22Z				VZ:881		biological_process											owl:Class	
GO:0045741	biolink:NamedThing	positive regulation of epidermal growth factor-activated receptor activity	Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity.	got7fsn_ti	positive regulation of EGFR activity|up-regulation of epidermal growth factor receptor activity|stimulation of epidermal growth factor receptor activity|upregulation of epidermal growth factor receptor activity|activation of epidermal growth factor receptor activity|positive regulation of epidermal growth factor receptor activity|positive regulation of EGF receptor activity|up regulation of epidermal growth factor receptor activity													biological_process											owl:Class	
GO:0045742	biolink:NamedThing	positive regulation of epidermal growth factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.	got7fsn_ti	positive regulation of EGF receptor signaling pathway|positive regulation of EGF receptor signalling pathway|activation of epidermal growth factor receptor signaling pathway|upregulation of epidermal growth factor receptor signaling pathway|up-regulation of epidermal growth factor receptor signaling pathway|positive regulation of EGFR signaling pathway|stimulation of epidermal growth factor receptor signaling pathway|up regulation of epidermal growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0008293	biolink:NamedThing	torso signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	torso signalling pathway													biological_process											owl:Class	
GO:0102847	biolink:NamedThing	1-18:3-2-16:2-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8309		molecular_function											owl:Class	
GO:0097464	biolink:NamedThing	thorny excrescence	Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads.	got7fsn_ti							pr	2012-12-21T08:00:13Z				NIF_Subcellular:nlx_467		cellular_component											owl:Class	
GO:0004449	biolink:NamedThing	isocitrate dehydrogenase (NAD+) activity	Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+.	got7fsn_ti	nicotinamide adenine dinucleotide isocitrate dehydrogenase activity|isocitrate:NAD+ oxidoreductase (decarboxylating)|isocitrate dehydrogenase (NAD) activity|NAD isocitric dehydrogenase activity|NAD-specific isocitrate dehydrogenase activity|NAD dependent isocitrate dehydrogenase activity|NAD isocitrate dehydrogenase activity|NAD-linked isocitrate dehydrogenase activity											Reactome:R-HSA-70967|EC:1.1.1.41|MetaCyc:ISOCITRATE-DEHYDROGENASE-NAD+-RXN|RHEA:23632		molecular_function											owl:Class	
GO:0018449	biolink:NamedThing	1-phenylethanol dehydrogenase activity	Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2.	got7fsn_ti												UM-BBD_reactionID:r0032		molecular_function											owl:Class	
GO:0097131	biolink:NamedThing	cyclin D1-CDK6 complex	A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:55:26Z						cellular_component											owl:Class	
GO:0033922	biolink:NamedThing	peptidoglycan beta-N-acetylmuramidase activity	Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues.	got7fsn_ti	exo-beta-N-acetylmuramidase activity|exo-beta-acetylmuramidase activity|peptidoglycan beta-N-acetylmuramoylexohydrolase activity|beta-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucoside acetamidodeoxyglucohydrolase activity											MetaCyc:3.2.1.92-RXN|EC:3.2.1.92		molecular_function											owl:Class	
GO:0061030	biolink:NamedThing	epithelial cell differentiation involved in mammary gland alveolus development	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.	got7fsn_ti							dph	2010-02-09T09:43:00Z						biological_process											owl:Class	
GO:0000011	biolink:NamedThing	vacuole inheritance	The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.	got7fsn_ti														biological_process											owl:Class	
GO:0031816	biolink:NamedThing	P2Y6 nucleotide receptor binding	Binding to a P2Y6 nucleotide receptor.	got7fsn_ti	P2Y6 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0061686	biolink:NamedThing	hercynylcysteine sulfoxide synthase activity	Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 <=> hercynylcysteine sulfoxide + H2O.	got7fsn_ti	hercynylcysteine sulfoxide synthase|hercynylcysteine S-oxide synthase	https://github.com/geneontology/go-ontology/issues/11163					dph	2015-03-06T15:08:51Z				EC:1.14.99.51|RHEA:42704		molecular_function											owl:Class	
GO:0009724	biolink:NamedThing	detection of abscisic acid stimulus	The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of abscisic acid stimulus													biological_process											owl:Class	
GO:0097645	biolink:NamedThing	amylin binding	Binding to amylin.	got7fsn_ti							pr	2014-09-08T20:53:03Z						molecular_function											owl:Class	
GO:0018875	biolink:NamedThing	anaerobic benzoate metabolic process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen.	got7fsn_ti	anaerobic benzoate metabolism											MetaCyc:CENTBENZCOA-PWY|UM-BBD_pathwayID:benz		biological_process											owl:Class	
GO:0043821	biolink:NamedThing	propionyl-CoA:succinate CoA-transferase activity	Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate.	got7fsn_ti	propionyl-CoA succinate CoA-transferase activity|propionyl-CoA:succinate CoA transferase activity											RHEA:28010|MetaCyc:RXN0-268		molecular_function											owl:Class	
GO:0044565	biolink:NamedThing	dendritic cell proliferation	The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.	got7fsn_ti							jl	2012-04-05T04:31:39Z						biological_process											owl:Class	
GO:0001777	biolink:NamedThing	T cell homeostatic proliferation	The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus.	got7fsn_ti	T-cell homeostatic proliferation|resting T cell proliferation|T-lymphocyte homeostatic proliferation|resting T-cell proliferation|T lymphocyte homeostatic proliferation													biological_process											owl:Class	
GO:0004498	biolink:NamedThing	calcidiol 1-monooxygenase activity	Catalysis of the reaction: calcidiol + H(+) + NADPH + O(2) = calcitriol + H(2)O + NADP(+).	got7fsn_ti	25-hydroxy D3-1alpha-hydroxylase activity|25-hydroxy vitamin D3 1-alpha-hydroxylase activity|1-hydroxylase-25-hydroxyvitamin D3 activity|calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)|cytochrome P450 CYP27B|25-hydroxyvitamin D3 1alpha-hydroxylase activity|25-hydroxycholecalciferol 1alpha-hydroxylase activity|25-hydroxycholecalciferol-1-hydroxylase activity|25-hydroxyvitamin D-1 alpha hydroxylase activity|25-hydroxycholecalciferol 1-hydroxylase activity|25-OHD-1 alpha-hydroxylase activity|25-hydroxycholecalciferol 1-monooxygenase activity											EC:1.14.15.18|RHEA:20573|Reactome:R-HSA-5602186|KEGG_REACTION:R03610|MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN|Reactome:R-HSA-209868		molecular_function											owl:Class	
GO:0004979	biolink:NamedThing	beta-endorphin receptor activity	Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC).	got7fsn_ti	mu-opioid receptor activity													molecular_function											owl:Class	
GO:0034539	biolink:NamedThing	3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity	Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr.	got7fsn_ti												EC:1.97.1.-|UM-BBD_reactionID:r0821		molecular_function											owl:Class	
GO:0018322	biolink:NamedThing	protein tyrosinylation	The addition of a tyrosine molecule to a protein amino acid.	got7fsn_ti	protein amino acid tyrosinylation													biological_process											owl:Class	
GO:0045735	biolink:NamedThing	nutrient reservoir activity	Functions in the storage of nutritious substrates.	got7fsn_ti	storage protein of fat body|storage protein|yolk protein				Note that this term can be used in place of the obsolete terms 'storage protein ; GO:0005187' and 'storage protein of fat body (sensu Insecta) ; GO:0008041'.									molecular_function											owl:Class	
GO:0015820	biolink:NamedThing	leucine transport	The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-leucine transport													biological_process											owl:Class	
GO:0030752	biolink:NamedThing	5-hydroxyfuranocoumarin 5-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin.	got7fsn_ti	furanocoumarin 5-O-methyltransferase activity|bergaptol methyltransferase activity|bergaptol 5-O-methyltransferase activity|furanocoumarin 5-methyltransferase activity|bergaptol O-methyltransferase activity|S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase activity|S-adenosyl-L-methionine:bergaptolO-methyltransferase activity|S-adenosyl-L-methionine:bergaptol O-methyltransferase activity|S-adenosyl-L-methionine:5-hydroxyfurocoumarin 5-O-methyltransferase activity|BMT activity										GO:0030764	MetaCyc:2.1.1.69-RXN|RHEA:11808|EC:2.1.1.69		molecular_function											owl:Class	
GO:0036050	biolink:NamedThing	peptidyl-lysine succinylation	The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine.	got7fsn_ti							bf	2011-12-12T09:51:27Z				RESID:AA0545		biological_process											owl:Class	
GO:0062144	biolink:NamedThing	L-propargylglycine synthase activity	Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H(+) + L-propargylglycine.	got7fsn_ti							dph	2019-09-02T16:48:52Z				RHEA:59892		molecular_function											owl:Class	
GO:0014728	biolink:NamedThing	regulation of the force of skeletal muscle contraction	Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges.	got7fsn_ti														biological_process											owl:Class	
GO:0031217	biolink:NamedThing	glucan 1,4-beta-glucosidase activity	Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units.	got7fsn_ti	exo-1,4-beta-D-glucosidase activity|exo-beta-1,4-glucosidase activity|exo-1,4-beta-glucosidase activity|1,4-beta-D-glucan glucohydrolase activity|beta-1,4-beta-glucanase activity|exo-beta-1,4-glucanase activity|exo-1,4-beta-glucanase activity|beta-1,4-glucanase activity|exocellulase activity											MetaCyc:3.2.1.74-RXN|EC:3.2.1.74		molecular_function											owl:Class	
GO:0102881	biolink:NamedThing	(+)-beta-barbatene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-barbatene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8421		molecular_function											owl:Class	
GO:0051264	biolink:NamedThing	mono-olein transacylation activity	Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.	got7fsn_ti	monoolein transacylation|mono-oleoylglycerol transacylase activity|acyl-CoA-independent mono-olein transacylation|monooleoylglycerol O-acyltransferase activity|MOG transacylation|mono-oleoylglycerol O-acyltransferase activity|monooleoylglycerol transacylase activity													molecular_function											owl:Class	
GO:0050312	biolink:NamedThing	sulfoacetaldehyde lyase activity	Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite.	got7fsn_ti	sulphoacetaldehyde lyase activity				Note that EC:4.4.1.12 was deleted from EC as the reaction is performed by sulfoacetaldehyde acetyltransferase (EC:2.3.3.15).							EC:4.4.1.-		molecular_function											owl:Class	
GO:0052596	biolink:NamedThing	phenethylamine:oxygen oxidoreductase (deaminating) activity	Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+.	got7fsn_ti												KEGG_REACTION:R02613|MetaCyc:AMINEPHEN-RXN|RHEA:25265|EC:1.4.3.21		molecular_function											owl:Class	
GO:0031132	biolink:NamedThing	serine 3-dehydrogenase activity	Catalysis of the reaction: L-serine + NADP(+) = L-alpha-formylglycine + 2 H(+) + NADPH.	got7fsn_ti	L-serine:NADP+ 3-oxidoreductase activity											EC:1.1.1.276|KEGG_REACTION:R06126|Wikipedia:Serine_3-dehydrogenase|RHEA:21596|MetaCyc:RXN0-2201		molecular_function											owl:Class	
GO:0150091	biolink:NamedThing	multiple spine synapse organization, multiple dendrites	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.	got7fsn_ti							bc	2018-08-08T15:05:29Z						biological_process											owl:Class	
GO:0050556	biolink:NamedThing	deacetylisoipecoside synthase activity	Catalysis of the reaction: deacetylisoipecoside + H(2)O = dopamine + secologanin.	got7fsn_ti	deacetylisoipecoside dopamine-lyase (secologanin-forming)|deacetylisoipecoside dopamine-lyase activity											EC:4.3.3.3|MetaCyc:4.3.3.3-RXN|RHEA:21756|KEGG_REACTION:R05750		molecular_function											owl:Class	
GO:0042370	biolink:NamedThing	thiamine diphosphate dephosphorylation	The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.	got7fsn_ti	thiamin diphosphate dephosphorylation|TPP dephosphorylation													biological_process											owl:Class	
GO:0042357	biolink:NamedThing	thiamine diphosphate metabolic process	The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.	got7fsn_ti	thiamine diphosphate metabolism|TPP metabolism|thiamin pyrophosphate metabolism|thiamine pyrophosphate metabolism|thiamin diphosphate metabolic process|thiamin pyrophosphate metabolic process|TPP metabolic process|thiamine pyrophosphate metabolic process|thiamin diphosphate metabolism													biological_process											owl:Class	
GO:0009102	biolink:NamedThing	biotin biosynthetic process	The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.	got7fsn_ti	vitamin H biosynthesis|biotin biosynthesis|vitamin H biosynthetic process|biotin synthesis|biotin formation|vitamin B7 biosynthesis|biotin anabolism|vitamin B7 biosynthetic process											MetaCyc:BIOTIN-SYNTHESIS-PWY		biological_process											owl:Class	
GO:0102243	biolink:NamedThing	ATP:geranylgeraniol phosphotransferase activity	Catalysis of the reaction: (E,E)-geranylgeraniol + ATP = H+ + all-trans-geranyl-geranyl monophosphate + ADP.	got7fsn_ti												RHEA:61660|MetaCyc:RXN-12325|EC:2.7.1.216		molecular_function											owl:Class	
GO:0007141	biolink:NamedThing	male meiosis I	A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.	got7fsn_ti	male meiosis I nuclear division													biological_process											owl:Class	
GO:0150025	biolink:NamedThing	oxidised low-density lipoprotein particle receptor activity	Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis.	got7fsn_ti	oxidised LDL receptor activity|oxidized low-density lipoprotein receptor activity|ox-LDL particle receptor activity|ox-LDL receptor activity|oxidized low-density lipoprotein particle receptor activity|oxidised low-density lipoprotein receptor activity|oxLDL particle receptor activity|oxidised LDL particle receptor activity|oxidized LDL particle receptor activity|oxLDL receptor activity|oxidized LDL receptor activity						bc	2018-02-06T14:17:33Z						molecular_function											owl:Class	
GO:1990515	biolink:NamedThing	3' transitive RNA interference	An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.	got7fsn_ti							jl	2014-10-09T15:31:01Z						biological_process											owl:Class	
GO:0016738	biolink:NamedThing	oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen.	got7fsn_ti												EC:1.19.6.-		molecular_function											owl:Class	
GO:0072429	biolink:NamedThing	response to intra-S DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling.	got7fsn_ti	intra-S DNA damage checkpoint effector process|response to signal involved in intra-S DNA damage checkpoint						mah	2010-12-08T04:31:56Z						biological_process											owl:Class	
GO:0035823	biolink:NamedThing	short tract gene conversion	A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor.	got7fsn_ti							bf	2011-05-04T01:05:35Z						biological_process											owl:Class	
GO:0060239	biolink:NamedThing	positive regulation of signal transduction involved in conjugation with cellular fusion	Any process that increases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0030759	biolink:NamedThing	methylquercetagetin 6-O-methyltransferase activity	Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase activity|6-OMT|flavonol 6-O-methyltransferase activity|flavonol 6-methyltransferase activity											MetaCyc:2.1.1.84-RXN|RHEA:18717|EC:2.1.1.84|KEGG_REACTION:R04505		molecular_function											owl:Class	
GO:0047548	biolink:NamedThing	2-methyleneglutarate mutase activity	Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate.	got7fsn_ti	alpha-methyleneglutarate mutase activity|2-methyleneglutarate carboxy-methylenemethylmutase activity											EC:5.4.99.4|MetaCyc:2-METHYLENEGLUTARATE-MUTASE-RXN|RHEA:13793|KEGG_REACTION:R03908		molecular_function											owl:Class	
GO:0034822	biolink:NamedThing	citronellal dehydrogenase activity	Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r1156		molecular_function											owl:Class	
GO:0070304	biolink:NamedThing	positive regulation of stress-activated protein kinase signaling cascade	Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.	got7fsn_ti	up regulation of stress-activated protein kinase signaling pathway|stimulation of stress-activated protein kinase signaling pathway|activation of stress-activated protein kinase signaling pathway|upregulation of stress-activated protein kinase signaling pathway|positive regulation of stress-activated protein kinase signalling pathway|positive regulation of stress-activated protein kinase signaling pathway|up-regulation of stress-activated protein kinase signaling pathway|positive regulation of SAPK signaling pathway													biological_process											owl:Class	
GO:0061236	biolink:NamedThing	mesonephric comma-shaped body morphogenesis	The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.	got7fsn_ti							dph	2010-08-19T03:00:21Z						biological_process											owl:Class	
GO:0047205	biolink:NamedThing	quinate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.	got7fsn_ti	hydroxycinnamoyl coenzyme A-quinate transferase activity|feruloyl-CoA:quinate O-(hydroxycinnamoyl)transferase activity											EC:2.3.1.99|MetaCyc:2.3.1.99-RXN|RHEA:15021		molecular_function											owl:Class	
GO:0019496	biolink:NamedThing	serine-isocitrate lyase pathway	A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide.	got7fsn_ti														biological_process											owl:Class	
GO:0102851	biolink:NamedThing	1-18:2-2-16:0-phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8318|EC:1.14.19.43		molecular_function											owl:Class	
GO:0070075	biolink:NamedThing	tear secretion	The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.	got7fsn_ti														biological_process											owl:Class	
GO:0042962	biolink:NamedThing	acridine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out).	got7fsn_ti	acridine efflux pump activity|acridine:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0120312	biolink:NamedThing	ciliary basal body segregation	The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites.	got7fsn_ti	microtubule basal body segregation|microtubule basal body separation|ciliary basal body separation						krc	2021-03-27T04:04:14Z						biological_process											owl:Class	
GO:0031485	biolink:NamedThing	myosin XV complex	A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.	got7fsn_ti														cellular_component											owl:Class	
GO:0001795	biolink:NamedThing	type IIb hypersensitivity	An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors.	got7fsn_ti	type V hypersensitivity				Note that some type IIa hypersensitivity response (GO:0001794) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIb hypersensitivity.									biological_process											owl:Class	
GO:0000761	biolink:NamedThing	conjugant formation	During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing.	got7fsn_ti														biological_process											owl:Class	
GO:0002869	biolink:NamedThing	positive regulation of B cell deletion	Any process that activates or increases the frequency, rate, or extent of B cell deletion.	got7fsn_ti	up-regulation of B cell deletion|positive regulation of B lymphocyte deletion|up regulation of B cell deletion|positive regulation of B-lymphocyte deletion|activation of B cell deletion|stimulation of B cell deletion|positive regulation of B-cell deletion|upregulation of B cell deletion													biological_process											owl:Class	
GO:0080061	biolink:NamedThing	indole-3-acetonitrile nitrilase activity	Catalysis of the reaction: indole-3-acetonitrile + 2 H2O = indole-3-acetic acid + NH3.	got7fsn_ti							dhl	2009-04-13T03:30:42Z				MetaCyc:RXN-1404|EC:3.5.5.1|RHEA:45776		molecular_function											owl:Class	
GO:0033354	biolink:NamedThing	chlorophyll cycle	A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates.	got7fsn_ti												MetaCyc:PWY-5068		biological_process											owl:Class	
GO:0015994	biolink:NamedThing	chlorophyll metabolic process	The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.	got7fsn_ti	chlorophyll metabolism													biological_process											owl:Class	
GO:0047830	biolink:NamedThing	D-octopine dehydrogenase activity	Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH.	got7fsn_ti	N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)|2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)|octopine:NAD oxidoreductase activity|ODH activity|octopine dehydrogenase activity|D-octopine synthase activity											MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN|RHEA:16285|EC:1.5.1.11		molecular_function											owl:Class	
GO:0046819	biolink:NamedThing	protein secretion by the type V secretion system	The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway.	got7fsn_ti	autotransporter system|protein secretion by the type V protein secretion system|type V protein secretion system|protein secretion by the autotransporter system													biological_process											owl:Class	
GO:0031245	biolink:NamedThing	extrinsic component of periplasmic side of cell outer membrane	The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to periplasmic side of cell outer membrane|extrinsic to internal leaflet of cell outer membrane|extrinsic to internal side of cell outer membrane|extrinsic to internal side of outer membrane													cellular_component											owl:Class	
GO:0039704	biolink:NamedThing	viral translational shunt	A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site.	got7fsn_ti	ribosomal shunt initiation pathway				This term is intended to annotate gene products involved in the process of viral translational shunt, not viral proteins produced by this translation process.		bf	2013-11-21T17:08:40Z				VZ:608		biological_process											owl:Class	
GO:0006808	biolink:NamedThing	regulation of nitrogen utilization	Any process that modulates the frequency, rate or extent of nitrogen utilization.	got7fsn_ti														biological_process											owl:Class	
GO:0051898	biolink:NamedThing	negative regulation of protein kinase B signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.	got7fsn_ti	down-regulation of protein kinase B signaling cascade|negative regulation of AKT signaling cascade|negative regulation of PKB signalling cascade|inhibition of protein kinase B signaling cascade|negative regulation of PKB signaling cascade|down regulation of protein kinase B signaling cascade|negative regulation of protein kinase B signalling cascade|negative regulation of protein kinase B signaling cascade|negative regulation of AKT signalling cascade|downregulation of protein kinase B signaling cascade													biological_process											owl:Class	
GO:0032767	biolink:NamedThing	copper-dependent protein binding	Binding to a protein or protein complex, in the presence of copper.	got7fsn_ti														molecular_function											owl:Class	
GO:0047055	biolink:NamedThing	salutaridine synthase activity	Catalysis of the reaction: (R)-reticuline + [reduced NADPH--hemoprotein reductase] + O2 -> salutaridine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	got7fsn_ti	(R)-reticuline oxidase (C-C phenol-coupling) activity	https://github.com/geneontology/go-ontology/issues/21133										MetaCyc:1.1.3.35-RXN|EC:1.14.19.67|RHEA:17713|KEGG_REACTION:R04696		molecular_function											owl:Class	
GO:0090221	biolink:NamedThing	mitotic spindle-templated microtubule nucleation	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle.	got7fsn_ti							tb	2010-01-13T10:42:37Z						biological_process											owl:Class	
GO:0098516	biolink:NamedThing	detection of high humidity	The series of events in which high humidity is detected and converted into a molecular signal.	got7fsn_ti							dos	2013-09-25T14:26:47Z						biological_process											owl:Class	
GO:0016428	biolink:NamedThing	tRNA (cytosine-5-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.	got7fsn_ti	transfer RNA cytosine 5-methyltransferase activity|transfer ribonucleate cytosine 5-methyltransferase activity|S-adenosyl-L-methionine:tRNA (cytosine-5-)-methyltransferase activity											Reactome:R-HSA-8932765|Reactome:R-HSA-6782388|Reactome:R-HSA-6785409|Reactome:R-HSA-6782419|Reactome:R-HSA-6785438		molecular_function											owl:Class	
GO:0051392	biolink:NamedThing	tRNA N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA.	got7fsn_ti	tRNA cytidine N-acetyltransferase activity													molecular_function											owl:Class	
GO:0017161	biolink:NamedThing	inositol-1,3,4-trisphosphate 4-phosphatase activity	Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate.	got7fsn_ti												Reactome:R-HSA-1855180|RHEA:43392		molecular_function											owl:Class	
GO:0031265	biolink:NamedThing	CD95 death-inducing signaling complex	A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.	got7fsn_ti	CD95 death-inducing signalling complex|Fas death-inducing signaling complex|CD95 DISC													cellular_component											owl:Class	
GO:0010308	biolink:NamedThing	acireductone dioxygenase (Ni2+-requiring) activity	Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + CO + formate.	got7fsn_ti	E-2 activity|ARD activity|acireductone dioxygenase activity|2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase activity|1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)											RHEA:14161|KEGG_REACTION:R07363|EC:1.13.11.53|MetaCyc:R146-RXN		molecular_function											owl:Class	
GO:0031737	biolink:NamedThing	CX3C chemokine receptor binding	Binding to a CX3C chemokine receptor.	got7fsn_ti	CX3C chemokine receptor ligand|fractalkine receptor binding													molecular_function											owl:Class	
GO:0018906	biolink:NamedThing	methyl tert-butyl ether metabolic process	The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent.	got7fsn_ti	methyl tert-butyl ether metabolism											UM-BBD_pathwayID:mtb		biological_process											owl:Class	
GO:0090403	biolink:NamedThing	oxidative stress-induced premature senescence	A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.	got7fsn_ti							tb	2011-01-05T02:37:57Z						biological_process											owl:Class	
GO:0018778	biolink:NamedThing	DL-2 haloacid dehalogenase activity	Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate.	got7fsn_ti												EC:3.8.1.10|MetaCyc:RXN-9150|UM-BBD_reactionID:r0382		molecular_function											owl:Class	
GO:0047338	biolink:NamedThing	UTP:xylose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate.	got7fsn_ti	UDP-xylose pyrophosphorylase activity|uridine diphosphoxylose pyrophosphorylase activity|xylose-1-phosphate uridylyltransferase activity|UTP:alpha-D-xylose-1-phosphate uridylyltransferase activity|UTP-xylose-1-phosphate uridylyltransferase activity|xylose 1-phosphate uridylyltransferase activity|uridylyltransferase, xylose 1-phosphate											EC:2.7.7.11|MetaCyc:2.7.7.11-RXN|RHEA:18389		molecular_function											owl:Class	
GO:0097663	biolink:NamedThing	SCF-Dia2/Pof3 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe).	got7fsn_ti							pr	2014-10-06T10:26:44Z						cellular_component											owl:Class	
GO:0102596	biolink:NamedThing	cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity	Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15379|EC:1.14.14.70|RHEA:41464		molecular_function											owl:Class	
GO:0018405	biolink:NamedThing	protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine	Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues.	got7fsn_ti	protein-keratan sulphate linkage via keratan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine											RESID:AA0247		biological_process											owl:Class	
GO:0071119	biolink:NamedThing	alpha7-beta1 integrin-nicotinamide riboside kinase complex	A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP).	got7fsn_ti	ITGA7-ITGB1-ITGB1BP3 complex						mah	2009-11-13T02:20:44Z						cellular_component											owl:Class	
GO:0051669	biolink:NamedThing	fructan beta-fructosidase activity	Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans.	got7fsn_ti	polysaccharide beta-fructofuranosidase activity|exo-beta-fructosidase activity|fructan exohydrolase activity|fructanase activity|fructan b-fructosidase activity|beta-D-fructan fructohydrolase activity|exo-beta-D-fructosidase activity											EC:3.2.1.80|MetaCyc:3.2.1.80-RXN		molecular_function											owl:Class	
GO:0061508	biolink:NamedThing	CDP phosphorylation	The process of introducing a phosphate group into CDP to produce a CTP.	got7fsn_ti							dph	2013-02-21T13:38:11Z						biological_process											owl:Class	
GO:1900686	biolink:NamedThing	regulation of gerfelin biosynthetic process	Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process.	got7fsn_ti	regulation of gerfelin biosynthesis|regulation of gerfelin formation|regulation of gerfelin synthesis|regulation of gerfelin anabolism						di	2012-05-22T04:49:44Z						biological_process											owl:Class	
GO:0090633	biolink:NamedThing	keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity	Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN.	got7fsn_ti	CMP-KDN synthetase activity|cytidine 5'-monophospho-2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid synthetase activity						tb	2015-03-19T15:05:54Z						molecular_function											owl:Class	
GO:0010859	biolink:NamedThing	calcium-dependent cysteine-type endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner.	got7fsn_ti														molecular_function											owl:Class	
GO:0036455	biolink:NamedThing	iron-sulfur transferase activity	Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor).	got7fsn_ti	Fe-S transferase activity						bf	2013-11-14T11:17:37Z				Reactome:R-HSA-2564828		molecular_function											owl:Class	
GO:0102797	biolink:NamedThing	geranial:oxygen oxidoreductase activity	Catalysis of the reaction: geranial + O2 + H2O = H+ + geranate + hydrogen peroxide.	got7fsn_ti												EC:1.2.3.1|MetaCyc:RXN-8093		molecular_function											owl:Class	
GO:1990780	biolink:NamedThing	cytoplasmic side of dendritic spine plasma membrane	The leaflet of the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface surrounding a dendritic spine.	got7fsn_ti							sl	2015-06-23T18:35:39Z						cellular_component											owl:Class	
GO:0004418	biolink:NamedThing	hydroxymethylbilane synthase activity	Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+).	got7fsn_ti	porphobilinogen ammonia-lyase (polymerizing)|uroporphyrinogen I synthase activity|uroporphyrinogen synthase activity|uroporphyrinogen synthetase activity|pre-uroporphyrinogen synthase activity|porphobilinogen deaminase activity|uroporphyrinogen I synthetase activity|(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)|HMB-synthase activity|(4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing) activity|porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)				Note that this function was formerly EC:4.3.1.8.							Reactome:R-HSA-189406|KEGG_REACTION:R00084|MetaCyc:OHMETHYLBILANESYN-RXN|RHEA:13185|EC:2.5.1.61		molecular_function											owl:Class	
GO:1905805	biolink:NamedThing	excitatory synapse pruning	The disaggregation of an excitatory synapse into its constituent components.	got7fsn_ti	synapse elimination|synapse clearance|synapse disassembly|synapse removal						tb	2017-01-11T22:03:06Z						biological_process											owl:Class	
GO:0102753	biolink:NamedThing	chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity	Catalysis of the reaction: H+ + chlorophyllide b(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate <=> geranylgeranyl-chlorophyll b + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-7673		molecular_function											owl:Class	
GO:0016844	biolink:NamedThing	strictosidine synthase activity	Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine.	got7fsn_ti	3-alpha(S)-strictosidine tryptamine-lyase activity|STR activity|strictosidine synthetase activity|3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming)											RHEA:15013|KEGG_REACTION:R03738|MetaCyc:STRICTOSIDINE-SYNTHASE-RXN|EC:4.3.3.2		molecular_function											owl:Class	
GO:0072508	biolink:NamedThing	trivalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of trivalent cations within an organism or cell.	got7fsn_ti					Note that this term was split from 'di-, tri-valent inorganic cation homeostasis ; GO:0055066' (sibling term 'divalent inorganic cation homeostasis' ; GO:0072507').		mah	2010-12-16T03:26:40Z						biological_process											owl:Class	
GO:0003864	biolink:NamedThing	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.	got7fsn_ti	ketopantoate hydroxymethyltransferase activity|alpha-ketoisovalerate hydroxymethyltransferase activity|dehydropantoate hydroxymethyltransferase activity|5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity|5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity|oxopantoate hydroxymethyltransferase activity											EC:2.1.2.11|RHEA:11824|MetaCyc:3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN		molecular_function											owl:Class	
GO:0080099	biolink:NamedThing	L-methionine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate.	got7fsn_ti	L-methionine:alpha-ketoglutarate aminotransferase activity				This reaction falls within the larger set of reactions associated with EC:2.6.1.5 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.5).		dhl	2009-04-23T03:51:20Z						molecular_function											owl:Class	
GO:0046114	biolink:NamedThing	guanosine biosynthetic process	The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution.	got7fsn_ti	guanosine biosynthesis|guanosine synthesis|guanosine formation|guanosine anabolism													biological_process											owl:Class	
GO:0061146	biolink:NamedThing	Peyer's patch morphogenesis	The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.	got7fsn_ti							dph	2010-05-26T06:46:23Z						biological_process											owl:Class	
GO:0009221	biolink:NamedThing	pyrimidine deoxyribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine deoxyribonucleotide formation|pyrimidine deoxyribonucleotide anabolism|pyrimidine deoxyribonucleotide synthesis|pyrimidine deoxyribonucleotide biosynthesis											MetaCyc:PWY0-166		biological_process											owl:Class	
GO:0035131	biolink:NamedThing	post-embryonic pelvic fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0000493	biolink:NamedThing	box H/ACA snoRNP assembly	The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.	got7fsn_ti	box H/ACA small nucleolar ribonucleoprotein complex assembly													biological_process											owl:Class	
GO:0035425	biolink:NamedThing	autocrine signaling	Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.	got7fsn_ti	autocrine signalling						bf	2010-03-29T02:15:52Z						biological_process											owl:Class	
GO:0070708	biolink:NamedThing	RNA cytidine insertion	The modification of an RNA molecule by insertion of a cytidine nucleotide.	got7fsn_ti	RNA C insertion						mah	2009-06-08T04:52:49Z						biological_process											owl:Class	
GO:0045162	biolink:NamedThing	clustering of voltage-gated sodium channels	The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.	got7fsn_ti	voltage-gated sodium channel clustering|Nav channel clustering|clustering of voltage gated sodium channels|clustering of voltage-dependent sodium channels													biological_process											owl:Class	
GO:0034130	biolink:NamedThing	toll-like receptor 1 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 1.	got7fsn_ti	toll-like receptor 1 signalling pathway|TLR1 signaling pathway													biological_process											owl:Class	
GO:0070123	biolink:NamedThing	transforming growth factor beta receptor activity, type III	Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors.	got7fsn_ti	type III TGF-beta receptor activity|betaglycan|type III TGFbeta receptor activity|type III transforming growth factor beta receptor activity|endoglin|transforming growth factor beta ligand binding to type III receptor													molecular_function											owl:Class	
GO:0016039	biolink:NamedThing	absorption of UV light	The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.	got7fsn_ti														biological_process											owl:Class	
GO:0061571	biolink:NamedThing	TDP phosphorylation	The process of introducing a phosphate group into TDP to produce a TTP.	got7fsn_ti							dph	2013-08-01T13:03:34Z						biological_process											owl:Class	
GO:0099569	biolink:NamedThing	presynaptic cytoskeleton	The portion of the cytoskeleton contained within the presynapse.	got7fsn_ti														cellular_component											owl:Class	
GO:0034931	biolink:NamedThing	1-hydroxypyrene methyltransferase activity	Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX.	got7fsn_ti												UM-BBD_reactionID:r0953		molecular_function											owl:Class	
GO:0103004	biolink:NamedThing	9,10-epoxystearate hydroxylase activity	Catalysis of the reaction: H+ + 9,10-epoxystearate + O2 + NADPH <=> 9,10-epoxy-18-hydroxystearate + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-9805		molecular_function											owl:Class	
GO:0070466	biolink:NamedThing	alpha2-beta1 integrin-alpha3(VI) complex	A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.	got7fsn_ti	ITGA2-ITGB1-COL6A3 complex													cellular_component											owl:Class	
GO:0006991	biolink:NamedThing	response to sterol depletion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti	sterol depletion response													biological_process											owl:Class	
GO:1990468	biolink:NamedThing	NuA3b histone acetyltransferase complex	A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.	got7fsn_ti							rb	2014-08-25T23:13:37Z						cellular_component											owl:Class	
GO:0061614	biolink:NamedThing	pri-miRNA transcription by RNA polymerase II	The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation.	got7fsn_ti	pri-miRNA transcription from RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14854					dph	2014-04-08T08:42:54Z						biological_process											owl:Class	
GO:0042388	biolink:NamedThing	gibberellic acid mediated signaling pathway, G-alpha-dependent	A series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.	got7fsn_ti	gibberellic acid mediated signalling, G-alpha-dependent													biological_process											owl:Class	
GO:0019327	biolink:NamedThing	lead sulfide oxidation	The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate.	got7fsn_ti	oxidation of lead sulfide|lead sulphide oxidation|oxidation of galena											MetaCyc:P301-PWY		biological_process											owl:Class	
GO:0000404	biolink:NamedThing	heteroduplex DNA loop binding	Binding to a DNA segment containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration.	got7fsn_ti	loop DNA binding													molecular_function											owl:Class	
GO:0033696	biolink:NamedThing	heterochromatin boundary formation	A process that forms a boundary that limits the spreading of heterochromatin along a chromosome.	got7fsn_ti	negative regulation of extent of heterochromatin formation|negative regulation of heterochromatin spreading|negative regulation of extent of heterochromatin assembly|regulation of heterochromatin spreading|regulation of extent of heterochromatin assembly|regulation of extent of heterochromatin formation|maintenance of heterochromatin boundaries	https://github.com/geneontology/go-ontology/issues/22028									GO:0031454			biological_process											owl:Class	
GO:0060844	biolink:NamedThing	arterial endothelial cell fate commitment	The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell.	got7fsn_ti							dph	2009-08-12T10:49:00Z						biological_process											owl:Class	
GO:0003178	biolink:NamedThing	coronary sinus valve development	The progression of the valve of the coronary sinus over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-08T11:21:43Z						biological_process											owl:Class	
GO:0006436	biolink:NamedThing	tryptophanyl-tRNA aminoacylation	The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0048671	biolink:NamedThing	negative regulation of collateral sprouting	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting.	got7fsn_ti	down-regulation of collateral sprouting|down regulation of collateral sprouting|inhibition of collateral sprouting|downregulation of collateral sprouting													biological_process											owl:Class	
GO:0015848	biolink:NamedThing	spermidine transport	The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0005785	biolink:NamedThing	signal recognition particle receptor complex	A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex.	got7fsn_ti	docking protein complex|SR complex													cellular_component											owl:Class	
GO:0035508	biolink:NamedThing	positive regulation of myosin-light-chain-phosphatase activity	Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity.	got7fsn_ti							bf	2010-04-30T10:55:05Z						biological_process											owl:Class	
GO:0032516	biolink:NamedThing	positive regulation of phosphoprotein phosphatase activity	Any process that activates or increases the activity of a phosphoprotein phosphatase.	got7fsn_ti	up regulation of phosphoprotein phosphatase activity|upregulation of protein phosphatase 2 activity|positive regulation of calcineurin activity|up-regulation of protein phosphatase type 2A activity|stimulation of protein phosphatase type 2A activity|positive regulation of protein phosphatase type 2A activity|activation of calcineurin activity|calcineurin activation|stimulation of phosphoprotein phosphatase activity|upregulation of protein phosphatase type 2B activity|activation of protein phosphatase type 2A activity|up-regulation of protein phosphatase 2 activity|up regulation of protein phosphatase type 2B activity|activation of protein phosphatase 3 activity|stimulation of protein phosphatase 2 activity|up regulation of calcineurin activity|positive regulation of protein phosphatase 2 activity|up-regulation of protein phosphatase type 2B activity|activation of protein phosphatase type 2B activity|up regulation of protein phosphatase 3 activity|upregulation of protein phosphatase type 2A activity|positive regulation of protein phosphatase 3 activity|positive regulation of protein phosphatase type 2B activity|up regulation of protein phosphatase 2 activity|stimulation of protein phosphatase type 2B activity|upregulation of phosphoprotein phosphatase activity|up-regulation of phosphoprotein phosphatase activity|activation of phosphoprotein phosphatase activity|up regulation of protein phosphatase type 2A activity										GO:0032514|GO:0034049			biological_process											owl:Class	
GO:0008240	biolink:NamedThing	tripeptidyl-peptidase activity	Catalysis of the release of an N-terminal tripeptide from a polypeptide.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681										EC:3.4.14.10|EC:3.4.14.9|MetaCyc:3.4.14.10-RXN|MetaCyc:3.4.14.9-RXN		molecular_function											owl:Class	
GO:0010364	biolink:NamedThing	regulation of ethylene biosynthetic process	Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process.	got7fsn_ti														biological_process											owl:Class	
GO:0031335	biolink:NamedThing	regulation of sulfur amino acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.	got7fsn_ti	regulation of sulfur amino acid metabolism													biological_process											owl:Class	
GO:0102457	biolink:NamedThing	cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> H+ + cyanidin 3,7-di-O-beta-D-glucoside betaine + vanillate.	got7fsn_ti												RHEA:35431|EC:2.4.1.300|MetaCyc:RXN-13969		molecular_function											owl:Class	
GO:0062022	biolink:NamedThing	mitotic cohesin ssDNA (lagging strand) loading	The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle.	got7fsn_ti	second-DNA capture						dph	2018-04-06T13:06:36Z						biological_process											owl:Class	
GO:0090566	biolink:NamedThing	protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in).	got7fsn_ti							tb	2014-04-08T15:08:43Z						molecular_function											owl:Class	
GO:0050344	biolink:NamedThing	trans-cinnamate 2-monooxygenase activity	Catalysis of the reaction: trans-cinnamate + H(+) + NADPH + O(2) = 2-coumarate + H(2)O + NADP(+).	got7fsn_ti	trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating)|cinnamate 2-monooxygenase activity|cinnamic acid 2-hydroxylase activity|cinnamate 2-hydroxylase activity|cinnamic 2-hydroxylase activity|trans-cinnamic acid 2-hydroxylase activity											MetaCyc:TRANS-CINNAMATE-2-MONOOXYGENASE-RXN|KEGG_REACTION:R02254|EC:1.14.13.14|RHEA:10956		molecular_function											owl:Class	
GO:0072523	biolink:NamedThing	purine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.	got7fsn_ti	purine-containing compound breakdown|purine and derivative catabolic process|purine-containing compound degradation|purine-containing compound catabolism						mah	2011-01-04T03:17:20Z						biological_process											owl:Class	
GO:0004023	biolink:NamedThing	alcohol dehydrogenase activity, metal ion-independent	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion.	got7fsn_ti														molecular_function											owl:Class	
GO:1901466	biolink:NamedThing	regulation of ferulate catabolic process	Any process that modulates the frequency, rate or extent of ferulate catabolic process.	got7fsn_ti	regulation of ferulate breakdown|regulation of ferulate catabolism|regulation of ferulate degradation						tt	2012-10-02T14:37:29Z						biological_process											owl:Class	
GO:0070412	biolink:NamedThing	R-SMAD binding	Binding to a receptor-regulated SMAD signaling protein.	got7fsn_ti	pathway-restricted SMAD binding|receptor regulated SMAD binding|receptor-regulated SMAD binding|pathway restricted SMAD binding													molecular_function											owl:Class	
GO:1990873	biolink:NamedThing	intrinsic component of plasma membrane of cell tip	The component of the plasma membrane surrounding the cell tip consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the plasma membrane surrounding the cell tip or some other covalently attached group such as a GPI anchor that is similarly embedded in the plasma membrane surrounding the cell tip.	got7fsn_ti							al	2015-09-29T10:06:25Z						cellular_component											owl:Class	
GO:0044577	biolink:NamedThing	xylose catabolic process to ethanol	The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol.	got7fsn_ti	xylose catabolism to ethanol						jl	2012-04-19T03:50:46Z						biological_process											owl:Class	
GO:0042341	biolink:NamedThing	cyanogenic glycoside metabolic process	The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.	got7fsn_ti	cyanogenic glycoside metabolism													biological_process											owl:Class	
GO:0043513	biolink:NamedThing	inhibin B complex	Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.	got7fsn_ti					Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'.									cellular_component											owl:Class	
GO:0070060	biolink:NamedThing	'de novo' actin filament nucleation	The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.	got7fsn_ti	formin-mediated actin filament nucleation|unbranched actin filament nucleation													biological_process											owl:Class	
GO:0047689	biolink:NamedThing	aspartate racemase activity	Catalysis of the reaction: L-aspartate = D-aspartate.	got7fsn_ti	D-aspartate racemase activity											MetaCyc:ASPARTATE-RACEMASE-RXN|EC:5.1.1.13|RHEA:14973|KEGG_REACTION:R00491		molecular_function											owl:Class	
GO:0002248	biolink:NamedThing	connective tissue replacement involved in inflammatory response wound healing	The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared that contribute to an inflammatory response.	got7fsn_ti	connective tissue replacement during inflammatory response|fibrosis during inflammatory response													biological_process											owl:Class	
GO:0039003	biolink:NamedThing	pronephric field specification	The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop.	got7fsn_ti	pronephric kidney field specification						bf	2010-07-02T09:28:16Z						biological_process											owl:Class	
GO:0042585	biolink:NamedThing	germinal vesicle	The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.	got7fsn_ti	primary oocyte nucleus													cellular_component											owl:Class	
GO:0075069	biolink:NamedThing	adhesion of symbiont infection cushion to host	The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	adhesion of symbiont infection cushion to host during symbiotic interaction				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0071137	biolink:NamedThing	alphaV-beta3 integrin-CD98 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98.	got7fsn_ti	ITGAV-ITGB3-SLC3A2 complex						mah	2009-11-13T02:29:59Z						cellular_component											owl:Class	
GO:0039022	biolink:NamedThing	pronephric duct development	The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.	got7fsn_ti							bf	2010-07-02T10:15:03Z						biological_process											owl:Class	
GO:0052754	biolink:NamedThing	GTP:coenzyme F420 guanyltransferase activity	Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate.	got7fsn_ti	GTP:coenzyme F420 guanylyltransferase activity|coenzyme F390-G synthetase activity						ai	2011-09-22T03:25:30Z						molecular_function											owl:Class	
GO:0047532	biolink:NamedThing	2,5-dioxopiperazine hydrolase activity	Catalysis of the reaction: 2,5-dioxopiperazine + H(2)O = glycylglycine.	got7fsn_ti	cyclo(Gly-Gly) hydrolase activity|2,5-dioxopiperazine amidohydrolase activity|cyclo(glycylglycine) hydrolase activity											EC:3.5.2.13|RHEA:21808|MetaCyc:25-DIOXOPIPERAZINE-HYDROLASE-RXN|KEGG_REACTION:R03810		molecular_function											owl:Class	
GO:0140698	biolink:NamedThing	attachment of telomeric heterochromatin to nuclear envelope	The process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.	got7fsn_ti	heterochromatin organization|attachment of telomeric chromatin to nuclear envelope|attachment of telomeres to nuclear envelope	https://github.com/geneontology/go-ontology/issues/22043					pg	2021-08-26T14:46:17Z						biological_process											owl:Class	
GO:0010495	biolink:NamedThing	long-distance posttranscriptional gene silencing	A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place.	got7fsn_ti	long-distance propagation of posttranscriptional gene silencing													biological_process											owl:Class	
GO:0042826	biolink:NamedThing	histone deacetylase binding	Binding to histone deacetylase.	got7fsn_ti														molecular_function											owl:Class	
GO:0102200	biolink:NamedThing	N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity	Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate.	got7fsn_ti												MetaCyc:RXN-12116|RHEA:33159|EC:3.1.4.54		molecular_function											owl:Class	
GO:0035171	biolink:NamedThing	lamellocyte differentiation	The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.	got7fsn_ti	lamellocyte cell differentiation													biological_process											owl:Class	
GO:0034999	biolink:NamedThing	oligosaccharyltransferase II complex	An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes.	got7fsn_ti	OSTCII													cellular_component											owl:Class	
GO:0008752	biolink:NamedThing	FMN reductase activity	Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+.	got7fsn_ti	NAD(P)H-FMN reductase activity|SsuE|NAD(P)H:flavin oxidoreductase activity|NAD(P)H(2):FMN oxidoreductase activity|NAD(P)H2 dehydrogenase (FMN)|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide (phosphate)) reductase activity|NAD(P)H-dependent FMN reductase activity|NAD(P)H dehydrogenase (FMN) activity|flavin mononucleotide reductase activity|FMNH2:NAD(P)+ oxidoreductase activity|riboflavine mononucleotide reductase activity|NAD(P)H(2) dehydrogenase (FMN) activity|riboflavin mononucleotide reductase activity|flavine mononucleotide reductase activity|NAD(P)H:FMN oxidoreductase activity|NAD(P)H2:FMN oxidoreductase activity											EC:1.5.1.39		molecular_function											owl:Class	
GO:0036243	biolink:NamedThing	succinate-semialdehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+.	got7fsn_ti	succinate semialdehyde:NADP+ oxidoreductase activity|succinic semialdehyde dehydrogenase (NADP+) activity|succinyl semialdehyde dehydrogenase (NADP+) activity|NADP-dependent succinate-semialdehyde dehydrogenase activity				This function is similar to EC:1.2.1.24 [succinate-semialdehyde dehydrogenase (NAD+)], and EC:1.2.1.16 [succinate-semialdehyde dehydrogenase (NAD(P)+)], but is specific for NADP+.		bf	2012-05-23T02:47:52Z				RHEA:13213|EC:1.2.1.79		molecular_function											owl:Class	
GO:0047372	biolink:NamedThing	acylglycerol lipase activity	Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.	got7fsn_ti	monoacylglycerol hydrolase activity|glycerol-ester acylhydrolase activity|monoglyceride hydrolase activity|fatty acyl monoester lipase activity|monoglyceridyllipase activity|monoacylglycerolipase activity|monoglyceridase activity|monoglyceride lipase activity|monoacylglycerol lipase activity											EC:3.1.1.23|Reactome:R-HSA-426032|Reactome:R-HSA-1482543|Reactome:R-HSA-163595|MetaCyc:3.1.1.23-RXN|Reactome:R-HSA-192422|Reactome:R-HSA-192430|Reactome:R-HSA-192434|RHEA:34019|Reactome:R-HSA-192425|Reactome:R-HSA-426043|Reactome:R-HSA-192475|Reactome:R-HSA-5694462		molecular_function											owl:Class	
GO:0033826	biolink:NamedThing	xyloglucan 4-glucosyltransferase activity	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage.	got7fsn_ti	xyloglucan glucosyltransferase activity|xyloglucan 4beta-D-glucosyltransferase activity|UDP-glucose:xyloglucan 1,4-beta-D-glucosyltransferase activity|UDPglucose:xyloglucan 1,4-beta-D-glucosyltransferase activity|uridine diphosphoglucose-xyloglucan 4beta-glucosyltransferase activity											EC:2.4.1.168|MetaCyc:2.4.1.168-RXN		molecular_function											owl:Class	
GO:0007415	biolink:NamedThing	defasciculation of motor neuron axon	Separation of a motor axon away from a bundle of axons known as a fascicle.	got7fsn_ti														biological_process											owl:Class	
GO:0103097	biolink:NamedThing	CYP79F1 trihomomethionine monooxygenase activity	Catalysis of the reaction: trihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 3 H2O + carbon dioxide + 2 NADP + 6-methylthiohexanaldoxime.	got7fsn_ti												MetaCyc:RXNQT-4310|RHEA:32723		molecular_function											owl:Class	
GO:0047322	biolink:NamedThing	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP.	got7fsn_ti	3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activity|ATP:hydroxymethylglutaryl-CoA reductase (NADPH) phosphotransferase activity|AMPK|hydroxymethylglutaryl coenzyme A reductase kinase activity|3-hydroxy-3-methylglutaryl-CoA reductase kinase activity|STK29|hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity|reductase kinase activity|HMG-CoA reductase kinase activity|beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activity|hydroxymethylglutaryl-CoA reductase kinase activity|hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity											MetaCyc:2.7.1.109-RXN|RHEA:23172|EC:2.7.11.31		molecular_function											owl:Class	
GO:0030963	biolink:NamedThing	peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine	The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine.	got7fsn_ti												RESID:AA0370		biological_process											owl:Class	
GO:0010499	biolink:NamedThing	proteasomal ubiquitin-independent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.	got7fsn_ti														biological_process											owl:Class	
GO:0052831	biolink:NamedThing	inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate.	got7fsn_ti							ai	2011-11-29T10:58:27Z				Reactome:R-HSA-1855159		molecular_function											owl:Class	
GO:0031503	biolink:NamedThing	protein-containing complex localization	A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.	got7fsn_ti	protein complex localisation|establishment and maintenance of protein complex localization|protein complex localization													biological_process											owl:Class	
GO:0102698	biolink:NamedThing	5-epi-aristolochene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-4781|RHEA:28635|EC:4.2.3.61		molecular_function											owl:Class	
GO:0002280	biolink:NamedThing	monocyte activation involved in immune response	The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	monocyte activation during immune response													biological_process											owl:Class	
GO:0033702	biolink:NamedThing	(+)-trans-carveol dehydrogenase activity	Catalysis of the reaction: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH.	got7fsn_ti	(+)-trans-carveol:NAD+ oxidoreductase activity											MetaCyc:RXN-9397|KEGG_REACTION:R06117|RHEA:14825|EC:1.1.1.275		molecular_function											owl:Class	
GO:1900802	biolink:NamedThing	cspyrone B1 biosynthetic process	The chemical reactions and pathways resulting in the formation of cspyrone B1.	got7fsn_ti	cspyrone B1 anabolism|cspyrone B1 formation|cspyrone B1 synthesis|cspyrone B1 biosynthesis						di	2012-06-04T09:51:06Z						biological_process											owl:Class	
GO:0002203	biolink:NamedThing	proteolysis by cytosolic proteases associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation.	got7fsn_ti					Note that a separate term covers proteolysis by the proteasome complex (proteasomal proteolysis associated with antigen processing and presentation ; GO:0002497).									biological_process											owl:Class	
GO:0010347	biolink:NamedThing	L-galactose-1-phosphate phosphatase activity	Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate.	got7fsn_ti												RHEA:26349|MetaCyc:RXNQT-4142		molecular_function											owl:Class	
GO:0046929	biolink:NamedThing	negative regulation of neurotransmitter secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.	got7fsn_ti	down-regulation of neurotransmitter secretion|down regulation of neurotransmitter secretion|inhibition of neurotransmitter secretion|conotoxin activity|downregulation of neurotransmitter secretion													biological_process											owl:Class	
GO:0000417	biolink:NamedThing	HIR complex	A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p.	got7fsn_ti	HIRA complex													cellular_component											owl:Class	
GO:0075506	biolink:NamedThing	entry of viral genome into host nucleus through nuclear pore complex via importin	Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery.	got7fsn_ti	entry of viral genome into host nucleus via cellular importin transport through the nuclear pore complex				This mechanism is used by some RNA viruses (e.g. Orthomyxoviridae), some dsDNA viruses (e.g. Polyomaviridae) and some ssRNA viruses (e.g. Lentivirus).		jl	2011-07-26T04:36:46Z						biological_process											owl:Class	
GO:0071135	biolink:NamedThing	alpha7-beta1 integrin-focal adhesion kinase complex	A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase.	got7fsn_ti	ITGA7-ITGB1-PTK2 complex						mah	2009-11-13T02:29:24Z						cellular_component											owl:Class	
GO:0097744	biolink:NamedThing	urate salt excretion	The elimination by an organism of urate salt or uric acid.	got7fsn_ti	urate excretion						pr	2016-10-27T11:35:59Z						biological_process											owl:Class	
GO:0000494	biolink:NamedThing	box C/D RNA 3'-end processing	Any process involved in forming the mature 3' end of a box C/D RNA molecule.	got7fsn_ti	box C/D snoRNA 3'-end processing|box C/D RNA 3' end processing|box C/D sRNA 3'-end processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0046608	biolink:NamedThing	carotenoid isomerase activity	Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids.	got7fsn_ti														molecular_function											owl:Class	
GO:0030911	biolink:NamedThing	TPR domain binding	Binding to a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.	got7fsn_ti	tetratricopeptide repeat domain binding													molecular_function											owl:Class	
GO:0061479	biolink:NamedThing	response to reverse transcriptase inhibitor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.	got7fsn_ti							dph	2012-11-07T09:10:51Z						biological_process											owl:Class	
GO:0051266	biolink:NamedThing	sirohydrochlorin ferrochelatase activity	Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin.	got7fsn_ti	sirohydrochlorin ferro-lyase activity|Met8P|SirB|CysG|siroheme synthase activity|siroheme ferro-lyase (sirohydrochlorin-forming)											RHEA:24360|MetaCyc:SIROHEME-FERROCHELAT-RXN|EC:4.99.1.4|KEGG_REACTION:R02864		molecular_function											owl:Class	
GO:0009703	biolink:NamedThing	nitrate reductase (NADH) activity	Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+.	got7fsn_ti	NADH-nitrate reductase activity|assimilatory NADH:nitrate reductase activity|NADH:nitrate oxidoreductase activity|assimilatory nitrate reductase activity|nitrate reductase (NADH2)|NADH:nitrate reductase activity|NADH-dependent nitrate reductase activity|nitrate reductase (NADH(2)) activity|nitrite:NAD+ oxidoreductase activity|assimilatory NADH: nitrate reductase activity				Note that this function was formerly EC:1.6.6.1.							EC:1.7.1.1|RHEA:17913|MetaCyc:NITRATE-REDUCTASE-NADH-RXN		molecular_function											owl:Class	
GO:0034902	biolink:NamedThing	endosulfan sulfate hydrolase activity	Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite.	got7fsn_ti												UM-BBD_reactionID:r1387		molecular_function											owl:Class	
GO:0018266	biolink:NamedThing	GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GPI anchor synthesis via N-aspartyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-aspartyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-aspartyl-glycosylphosphatidylinositolethanolamine											RESID:AA0159		biological_process											owl:Class	
GO:0070223	biolink:NamedThing	sulfide oxidation, using sulfur dioxygenase	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase.	got7fsn_ti	sulphide oxidation, using sulfur dioxygenase											MetaCyc:PWY-5285		biological_process											owl:Class	
GO:0021671	biolink:NamedThing	rhombomere 7 morphogenesis	The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0047526	biolink:NamedThing	2'-hydroxyisoflavone reductase activity	Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+.	got7fsn_ti	NADPH:2'-hydroxyisoflavone oxidoreductase activity|isoflavone reductase activity|vestitone:NADP+ oxidoreductase activity|2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase activity											RHEA:22560|MetaCyc:2-HYDROXYISOFLAVONE-REDUCTASE-RXN|EC:1.3.1.45		molecular_function											owl:Class	
GO:0099573	biolink:NamedThing	glutamatergic postsynaptic density	The post-synaptic specialization of a glutamatergic excitatory synapse.	got7fsn_ti	postsynaptic specialization, glutamatergic neuron-to-neuron synapse													cellular_component											owl:Class	
GO:0050305	biolink:NamedThing	strombine dehydrogenase activity	Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H(2)O + NAD(+) = glycine + H(+) + NADH + pyruvate.	got7fsn_ti	strombine[N-(carboxymethyl)-D-alanine]dehydrogenase activity|N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase activity|N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming)											EC:1.5.1.22|RHEA:14061|KEGG_REACTION:R00368|MetaCyc:STROMBINE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0055004	biolink:NamedThing	atrial cardiac myofibril assembly	The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.	got7fsn_ti	atrial heart myofibril development|atrial cardiac myofibril development													biological_process											owl:Class	
GO:1990125	biolink:NamedThing	DiaA complex	A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation.	got7fsn_ti	DiaA homotetramer						bhm	2013-06-13T14:03:54Z						cellular_component											owl:Class	
GO:0071960	biolink:NamedThing	maintenance of mitotic sister chromatid cohesion, centromeric	The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.	got7fsn_ti	maintenance of mitotic sister chromatin cohesion at centromere|maintenance of centromeric mitotic sister chromatin cohesion|maintenance of sister chromatin cohesion at centromere at mitosis						mah	2011-06-01T04:10:59Z						biological_process											owl:Class	
GO:0042843	biolink:NamedThing	D-xylose catabolic process	The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide.	got7fsn_ti	D-xylose catabolism|D-xylose breakdown|D-xylose degradation													biological_process											owl:Class	
GO:0033412	biolink:NamedThing	UAG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UAG codon.	got7fsn_ti	TAG codon-amino acid adaptor activity				Note that in the standard genetic code, TAG is a stop codon (amber) and is not normally read by a tRNA.									molecular_function											owl:Class	
GO:0018423	biolink:NamedThing	protein C-terminal leucine carboxyl O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.	got7fsn_ti	protein-leucine O-methyltransferase activity|protein phosphatase methyltransferase activity											Reactome:R-HSA-8856945		molecular_function											owl:Class	
GO:0047811	biolink:NamedThing	D-alanine gamma-glutamyltransferase activity	Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH(4)(+).	got7fsn_ti	L-glutamine:D-alanine gamma-glutamyltransferase activity|D-alanine g-glutamyltransferase activity											RHEA:23556|KEGG_REACTION:R01149|EC:2.3.2.14|MetaCyc:D-ALANINE-GAMMA-GLUTAMYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0016457	biolink:NamedThing	dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome	The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster.	got7fsn_ti	dosage compensation complex assembly during dosage compensation by hyperactivation of X chromosome													biological_process											owl:Class	
GO:0047377	biolink:NamedThing	5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity	Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+).	got7fsn_ti	5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene acetylhydrolase activity|diacetoxybutynylbithiophene acetate esterase activity|3,4-diacetoxybutinylbithiophene:4-acetate esterase activity											KEGG_REACTION:R04525|EC:3.1.1.66|MetaCyc:3.1.1.66-RXN|RHEA:16313		molecular_function											owl:Class	
GO:0050094	biolink:NamedThing	methionine-glyoxylate transaminase activity	Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine.	got7fsn_ti	MGAT activity|L-methionine:glyoxylate aminotransferase activity|methionine-glyoxylate aminotransferase activity											KEGG_REACTION:R00652|EC:2.6.1.73|RHEA:22884|MetaCyc:METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN		molecular_function											owl:Class	
GO:0018755	biolink:NamedThing	2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity	Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-.	got7fsn_ti														molecular_function											owl:Class	
GO:0070552	biolink:NamedThing	BRISC complex	A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.	got7fsn_ti														cellular_component											owl:Class	
GO:0072669	biolink:NamedThing	tRNA-splicing ligase complex	A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.	got7fsn_ti	tRNA splicing ligase complex						mah	2011-02-18T10:55:26Z				MetaCyc:ENTMULTI-CPLX		cellular_component											owl:Class	
GO:0046503	biolink:NamedThing	glycerolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone.	got7fsn_ti	glycerolipid catabolism|glycerolipid degradation|glycerolipid breakdown													biological_process											owl:Class	
GO:0035635	biolink:NamedThing	entry of bacterium into host cell	The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	invasion of bacteria into host cell|bacterial entry into host cell						bf	2011-01-13T02:26:54Z						biological_process											owl:Class	
GO:0047381	biolink:NamedThing	dodecanoyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein].	got7fsn_ti	lauryl-acyl-carrier protein hydrolase activity|dodecanoyl-acyl-carrier-protein hydrolase activity|lauryl-acyl-carrier-protein hydrolase activity|lauroyl-[acyl-carrier-protein] hydrolase activity|dodecyl-[acyl-carrier protein] hydrolase activity|dodecanoyl-ACP hydrolase activity|dodecyl-acyl-carrier protein hydrolase|lauroyl-ACP hydrolase activity|dodecanoyl-[acyl-carrier protein] hydrolase activity|lauryl-[acyl-carrier protein] hydrolase activity										GO:0016294	EC:3.1.2.21|MetaCyc:3.1.2.21-RXN|RHEA:30119		molecular_function											owl:Class	
GO:0017172	biolink:NamedThing	cysteine dioxygenase activity	Catalysis of the reaction: L-cysteine + O(2) = 3-sulfino-L-alanine + H(+).	got7fsn_ti												EC:1.13.11.20|RHEA:20441|KEGG_REACTION:R00893|MetaCyc:CYSTEINE-DIOXYGENASE-RXN|Reactome:R-HSA-1614645		molecular_function											owl:Class	
GO:0039716	biolink:NamedThing	viroplasm viral factory	A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae.	got7fsn_ti							bf	2013-12-19T15:22:29Z				Wikipedia:Viroplasm		cellular_component											owl:Class	
GO:0015670	biolink:NamedThing	carbon dioxide transport	The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1990045	biolink:NamedThing	sclerotium development	The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions.	got7fsn_ti							pr	2013-02-15T15:30:00Z						biological_process											owl:Class	
GO:0002545	biolink:NamedThing	chronic inflammatory response to non-antigenic stimulus	A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma.	got7fsn_ti														biological_process											owl:Class	
GO:0008143	biolink:NamedThing	poly(A) binding	Binding to a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.	got7fsn_ti	polyadenylate binding|poly-A binding|poly(A) binding, within an RNA molecule|poly(rA) binding													molecular_function											owl:Class	
GO:0050561	biolink:NamedThing	glutamate-tRNA(Gln) ligase activity	Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP.	got7fsn_ti	L-glutamate:tRNAGlx ligase (AMP-forming)|glutamate-tRNAGln ligase activity|nondiscriminating glutamyl-tRNA synthetase activity											MetaCyc:6.1.1.24-RXN|EC:6.1.1.24|RHEA:18397		molecular_function											owl:Class	
GO:0102139	biolink:NamedThing	2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase activity	Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + (2E)-2-hydroxypenta-2,4-dienoate.	got7fsn_ti												MetaCyc:RXN-11543|EC:3.7.1.13|RHEA:27870		molecular_function											owl:Class	
GO:0120221	biolink:NamedThing	maintenance of ciliary planar beating movement pattern	Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement.	got7fsn_ti					Note that we deem cilium and microtubule-based flagellum to be equivalent.		krc	2019-12-10T21:34:54Z						biological_process											owl:Class	
GO:1990454	biolink:NamedThing	L-type voltage-gated calcium channel complex	A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.	got7fsn_ti	cardiac muscle L-type voltage-gated calcium channel complex|skeletal muscle L-type voltage-gated calcium channel complex				Examples of this are CACNA1S, CACNA2D1, CACNB1, CACNG1 in rabbit (UniProt symbol P07293, P13806, P19517 and P19518) in PMID:12946355 (inferred from direct assay).		anm	2014-08-12T17:22:10Z						cellular_component											owl:Class	
GO:0060962	biolink:NamedThing	regulation of ribosomal protein gene transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.	got7fsn_ti	regulation of ribosomal protein gene transcription from RNA polymerase II promoter						dph	2009-10-05T03:00:40Z						biological_process											owl:Class	
GO:0042565	biolink:NamedThing	RNA nuclear export complex	A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore.	got7fsn_ti														cellular_component											owl:Class	
GO:0039553	biolink:NamedThing	suppression by virus of host chemokine activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host chemokine activity.	got7fsn_ti	down-regulation by virus of host chemokine activity|downregulation by virus of host chemokine activity|negative regulation by virus of host chemokine activity|inhibition of host chemokines by virus|inhibition by virus of host chemokine activity						bf	2012-02-28T01:29:55Z				VZ:813		biological_process											owl:Class	
GO:0039518	biolink:NamedThing	suppression by virus of host cytokine activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host cytokine activity.	got7fsn_ti	down-regulation by virus of host cytokine activity|inhibition by virus of host cytokine activity|downregulation by virus of host cytokine activity|negative regulation by virus of host cytokine activity						bf	2011-06-22T04:09:41Z						biological_process											owl:Class	
GO:0071888	biolink:NamedThing	macrophage apoptotic process	Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues.	got7fsn_ti	activation-induced cell death|AICD|macrophage apoptosis				Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).		mah	2010-09-14T12:50:40Z						biological_process											owl:Class	
GO:0003243	biolink:NamedThing	circumferential growth involved in left ventricle morphogenesis	The morphogenetic growth in which the left ventricle grows expanding its external boundary.	got7fsn_ti							dph	2009-10-13T11:33:09Z						biological_process											owl:Class	
GO:0045759	biolink:NamedThing	negative regulation of action potential	Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti	inhibition of action potential|down-regulation of action potential|downregulation of action potential|down regulation of action potential													biological_process											owl:Class	
GO:0035764	biolink:NamedThing	dorsal motor nucleus of vagus nerve formation	The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti							bf	2011-03-29T02:48:26Z						biological_process											owl:Class	
GO:0043770	biolink:NamedThing	demethylmenaquinone methyltransferase activity	Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.163		molecular_function											owl:Class	
GO:0033768	biolink:NamedThing	SUMO-targeted ubiquitin ligase complex	A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.	got7fsn_ti														cellular_component											owl:Class	
GO:0097063	biolink:NamedThing	cadmium ion sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++).	got7fsn_ti							pr	2011-06-08T09:46:14Z						molecular_function											owl:Class	
GO:0046870	biolink:NamedThing	cadmium ion binding	Binding to a cadmium ion (Cd).	got7fsn_ti	Cd ion binding|copper/cadmium binding|cadmium binding													molecular_function											owl:Class	
GO:0032427	biolink:NamedThing	GBD domain binding	Binding to a GTPase protein binding domain (GDB) domain. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac.	got7fsn_ti	PMD binding|P21-Rho-binding domain binding|Cdc42/Rac interactive binding motif binding|CRIB motif binding													molecular_function											owl:Class	
GO:0036324	biolink:NamedThing	vascular endothelial growth factor receptor-2 signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	VEGFR2 signaling pathway|KDR signaling pathway|VEGFR-2 signaling pathway|FLK-1 signaling pathway						bf	2012-09-04T15:15:40Z						biological_process											owl:Class	
GO:0033918	biolink:NamedThing	kappa-carrageenase activity	Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.	got7fsn_ti	kappa-carrageenan 4-beta-D-glycanohydrolase (configuration-retaining) activity|kappa-carrageenan 4-beta-D-glycanohydrolase activity											MetaCyc:3.2.1.83-RXN|EC:3.2.1.83		molecular_function											owl:Class	
GO:0001836	biolink:NamedThing	release of cytochrome c from mitochondria	The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.	got7fsn_ti					The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that are directly involved in this process. An example is Drp1 (DNM1L, UniProt symbol O00429) in PMID:20850011.									biological_process											owl:Class	
GO:0036522	biolink:NamedThing	negative regulation by symbiont of host protein localization to phagocytic vesicle	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	suppression of host protein localisation to phagosome|disruption of host protein localisation to phagosome|inhibition of host protein localisation to phagosome						bf	2016-06-06T14:49:51Z						biological_process											owl:Class	
GO:0021808	biolink:NamedThing	cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration	The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration.	got7fsn_ti	cytosolic calcium signalling involved in the initiation of cell movement in glial-mediated radial cell migration													biological_process											owl:Class	
GO:0003979	biolink:NamedThing	UDP-glucose 6-dehydrogenase activity	Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate.	got7fsn_ti												KEGG_REACTION:R00286|MetaCyc:UGD-RXN|RHEA:23596|Reactome:R-HSA-173597|EC:1.1.1.22		molecular_function											owl:Class	
GO:0018473	biolink:NamedThing	cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity	Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid.	got7fsn_ti												UM-BBD_reactionID:r0744		molecular_function											owl:Class	
GO:0034000	biolink:NamedThing	chondroitin-sulfate-ABC endolyase activity	Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.	got7fsn_ti	chondroitin sulfate ABC lyase activity|chondroitin ABC eliminase activity|chondroitin sulfate ABC endoeliminase activity|ChS ABC lyase activity|chondroitinase ABC activity|chondroitin sulfate ABC endolyase activity|ChS ABC lyase I activity|chondroitinase activity											EC:4.2.2.20|MetaCyc:4.2.2.20-RXN		molecular_function											owl:Class	
GO:0097186	biolink:NamedThing	amelogenesis	The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.	got7fsn_ti	enamel development						pr	2011-11-21T09:01:24Z						biological_process											owl:Class	
GO:0030544	biolink:NamedThing	Hsp70 protein binding	Binding to a Hsp70 protein, heat shock proteins around 70kDa in size.	got7fsn_ti														molecular_function											owl:Class	
GO:0034748	biolink:NamedThing	Par3-APC-KIF3A complex	A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity.	got7fsn_ti					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.									cellular_component											owl:Class	
GO:0043889	biolink:NamedThing	(S)-3-O-geranylgeranylglyceryl phosphate synthase activity	Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate.	got7fsn_ti	(S)-GGGP synthase activity|GGGPS|GGGP synthase activity|(S)-3-O-geranylgeranylglycerylphosphate synthase activity				This function is involved in archaeal lipid synthesis.									molecular_function											owl:Class	
GO:0050350	biolink:NamedThing	trihydroxystilbene synthase activity	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2.	got7fsn_ti	malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)|stilbene synthase activity|resveratrol synthase activity											MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN|RHEA:11936|EC:2.3.1.95		molecular_function											owl:Class	
GO:0080133	biolink:NamedThing	midchain alkane hydroxylase activity	Catalysis of the conversion of an alkane to a secondary alcohol.	got7fsn_ti							dhl	2009-05-06T04:46:17Z						molecular_function											owl:Class	
GO:0010839	biolink:NamedThing	negative regulation of keratinocyte proliferation	Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0031609	biolink:NamedThing	cytosolic proteasome core complex, beta-subunit complex	The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0010515	biolink:NamedThing	negative regulation of induction of conjugation with cellular fusion	Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0015349	biolink:NamedThing	thyroid hormone transmembrane transporter activity	Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.	got7fsn_ti												Reactome:R-HSA-879575|Reactome:R-HSA-9631987		molecular_function											owl:Class	
GO:0097013	biolink:NamedThing	phagocytic vesicle lumen	The volume enclosed by the membrane of a phagocytic vesicle.	got7fsn_ti							pr	2011-03-22T01:44:47Z						cellular_component											owl:Class	
GO:0030767	biolink:NamedThing	3-hydroxyanthranilate 4-C-methyltransferase activity	Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase activity|3-hydroxyanthranilate 4-methyltransferase activity											RHEA:17833|EC:2.1.1.97|MetaCyc:2.1.1.97-RXN|KEGG_REACTION:R02667		molecular_function											owl:Class	
GO:0034959	biolink:NamedThing	endothelin maturation	The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15384												biological_process											owl:Class	
GO:0003240	biolink:NamedThing	conus arteriosus formation	The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.	got7fsn_ti							dph	2009-10-13T11:25:47Z						biological_process											owl:Class	
GO:0031878	biolink:NamedThing	type 1 somatostatin receptor binding	Binding to a type 1 somatostatin receptor.	got7fsn_ti	type 1 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0048270	biolink:NamedThing	methionine adenosyltransferase regulator activity	Binds to and modulates the activity of methionine adenosyltransferase.	got7fsn_ti	MAT regulator activity				See also the molecular function term 'methionine adenosyltransferase activity ; GO:0004478'.									molecular_function											owl:Class	
GO:0050973	biolink:NamedThing	detection of mechanical stimulus involved in equilibrioception	The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.	got7fsn_ti	equilibrioception, detection of mechanical stimulus|equilibrioception, sensory detection of mechanical stimulus|sensory detection of mechanical stimulus during equilibrioception|equilibrioception, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during equilibrioception													biological_process											owl:Class	
GO:0034012	biolink:NamedThing	FAD-AMP lyase (cyclizing) activity	Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate.	got7fsn_ti	FMN cyclase activity|FAD AMP-lyase (riboflavin-cyclic-4',5'-phosphate-forming) activity|FAD AMP-lyase (cyclic-FMN-forming) activity											EC:4.6.1.15|RHEA:13729		molecular_function											owl:Class	
GO:0008902	biolink:NamedThing	hydroxymethylpyrimidine kinase activity	Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+).	got7fsn_ti	hydroxymethylpyrimidine kinase (phosphorylating)|ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase activity											MetaCyc:OHMETPYRKIN-RXN|RHEA:23096|EC:2.7.1.49|KEGG_REACTION:R03471		molecular_function											owl:Class	
GO:0030590	biolink:NamedThing	first cell cycle pseudocleavage	A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms.	got7fsn_ti														biological_process											owl:Class	
GO:0034768	biolink:NamedThing	(E)-beta-ocimene synthase activity	Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate.	got7fsn_ti												EC:4.2.3.106|RHEA:32691|MetaCyc:RXN-5109		molecular_function											owl:Class	
GO:0098614	biolink:NamedThing	hydrogen selenide methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + hydrogen selenide => S-adenosyl-L-homocysteine + methaneselenol.	got7fsn_ti												Reactome:R-HSA-2408536		molecular_function											owl:Class	
GO:0070448	biolink:NamedThing	laricitrin 5'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin.	got7fsn_ti	S-adenosyl-L-methionine:myricetin O-methyltransferase activity|CrCOMT2|flavonoid 3',5'-O-dimethyltransferase activity				Note that this term represents one of two reactions that are grouped together in EC:2.1.1.267.							MetaCyc:RXN-8452|KEGG_REACTION:R06816|RHEA:25633|EC:2.1.1.267		molecular_function											owl:Class	
GO:0071962	biolink:NamedThing	mitotic sister chromatid cohesion, centromeric	The cell cycle process in which centromeres of sister chromatids are joined during mitosis.	got7fsn_ti	centromeric mitotic sister chromatin cohesion|mitotic sister chromatid cohesion at centromere|sister chromatid cohesion at centromere at mitosis						mah	2011-06-02T11:24:17Z						biological_process											owl:Class	
GO:0080115	biolink:NamedThing	myosin XI tail binding	Binding to the tail region of a myosin XI heavy chain.	got7fsn_ti							dhl	2009-04-27T03:31:45Z						molecular_function											owl:Class	
GO:0045353	biolink:NamedThing	interleukin-1 type II receptor antagonist activity	Blocks the binding of interleukin-1 to interleukin-1 type II receptors.	got7fsn_ti	IL-1ra type II													molecular_function											owl:Class	
GO:0051867	biolink:NamedThing	general adaptation syndrome, behavioral process	The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus.	got7fsn_ti	general adaptation syndrome, behavioral response|behavioural response during general adaptation syndrome|behavioral process during general adaptation syndrome|behavioural process during general adaptation syndrome|behavioral response during general adaptation syndrome|general adaptation syndrome, behavioural response|general adaptation syndrome, behavioural process													biological_process											owl:Class	
GO:0047889	biolink:NamedThing	ferredoxin-nitrate reductase activity	Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin.	got7fsn_ti	assimilatory nitrate reductase activity|nitrate (ferredoxin) reductase activity|nitrite:ferredoxin oxidoreductase activity|assimilatory ferredoxin-nitrate reductase activity											EC:1.7.7.2|MetaCyc:1.7.7.2-RXN|RHEA:21828		molecular_function											owl:Class	
GO:0052062	biolink:NamedThing	induction by symbiont of host phytoalexin production	The activation by a symbiont of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of phytoalexin production in other organism involved in symbiotic interaction|activation by organism of host phytoalexin production										GO:0052262			biological_process											owl:Class	
GO:0070316	biolink:NamedThing	regulation of G0 to G1 transition	A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.	got7fsn_ti														biological_process											owl:Class	
GO:0106078	biolink:NamedThing	histone succinyltransferase activity	Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone.	got7fsn_ti							hjd	2017-12-15T18:29:40Z						molecular_function											owl:Class	
GO:0003426	biolink:NamedThing	cytoskeleton polarization involved in growth plate cartilage chondrocyte division	A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.	got7fsn_ti							dph	2009-12-22T11:38:22Z						biological_process											owl:Class	
GO:0048722	biolink:NamedThing	anterior cibarial plate development	The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0102873	biolink:NamedThing	1-18:1-2-16:0-digalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:1-2-16:0-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.23|MetaCyc:RXN-8363		molecular_function											owl:Class	
GO:0039564	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2).	got7fsn_ti	suppression by virus of host STAT2 activity|inhibition of host STAT2 by virus|inhibition by virus of host STAT2 activity	https://github.com/geneontology/go-ontology/issues/21963					bf	2012-03-12T02:52:34Z						biological_process											owl:Class	
GO:0097536	biolink:NamedThing	thymus epithelium morphogenesis	The process in which the thymus epithelium is generated and organized.	got7fsn_ti	thymic epithelium morphogenesis						pr	2013-11-28T10:51:03Z						biological_process											owl:Class	
GO:0106255	biolink:NamedThing	hydroperoxy icosatetraenoate isomerase activity	A hydroperoxy icosatetraenoate <=> a hydroxy epoxy icosatrienoate.	got7fsn_ti							hjd	2020-03-20T14:00:30Z				EC:5.4.4.7|RHEA:55560		molecular_function											owl:Class	
GO:0010514	biolink:NamedThing	induction of conjugation with cellular fusion	The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types.	got7fsn_ti														biological_process											owl:Class	
GO:0048285	biolink:NamedThing	organelle fission	The creation of two or more organelles by division of one organelle.	got7fsn_ti														biological_process											owl:Class	
GO:0103100	biolink:NamedThing	UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-).	got7fsn_ti												MetaCyc:RXNQT-4325|EC:2.4.1.195		molecular_function											owl:Class	
GO:0050122	biolink:NamedThing	N-acylhexosamine oxidase activity	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + O(2) = N-acetyl-D-glucosaminate + H(2)O(2) + H(+).	got7fsn_ti	N-acyl-D-hexosamine:oxygen 1-oxidoreductase activity|N-acyl-beta-D-hexosamine:oxygen 1-oxidoreductase activity|N-acyl-D-hexosamine oxidase activity											KEGG_REACTION:R01203|MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN|RHEA:13029|EC:1.1.3.29		molecular_function											owl:Class	
GO:0090612	biolink:NamedThing	cAMP deaminase activity	Catalysis of the reaction: cyclic adenosine monophosphate + H2O = cyclic inosine monophosphate + NH3.	got7fsn_ti	cyclic adenosine monophosphate deaminase activity						tb	2014-10-23T15:46:42Z				EC:3.5.4.46|RHEA:22908		molecular_function											owl:Class	
GO:0014814	biolink:NamedThing	axon regeneration at neuromuscular junction	The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.	got7fsn_ti														biological_process											owl:Class	
GO:1990528	biolink:NamedThing	Rvs161p-Rvs167p complex	A protein complex that is involved in endocytosis in the yeast S. cerevisiae.	got7fsn_ti							rb	2014-11-05T23:11:32Z						cellular_component											owl:Class	
GO:0072059	biolink:NamedThing	cortical collecting duct development	The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.	got7fsn_ti							mah	2010-01-25T04:07:07Z						biological_process											owl:Class	
GO:0031852	biolink:NamedThing	mu-type opioid receptor binding	Binding to a mu-type opioid receptor.	got7fsn_ti	mu-type opioid receptor ligand|morphine receptor binding													molecular_function											owl:Class	
GO:0042039	biolink:NamedThing	vanadium incorporation into metallo-sulfur cluster	The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n).	got7fsn_ti	vanadium incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0050582	biolink:NamedThing	xylitol oxidase activity	Catalysis of the reaction: xylitol + O2 = xylose + H2O2.	got7fsn_ti	xylitol:oxygen oxidoreductase activity											EC:1.1.3.41|MetaCyc:1.1.3.41-RXN		molecular_function											owl:Class	
GO:0018395	biolink:NamedThing	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine.	got7fsn_ti												RESID:AA0028		biological_process											owl:Class	
GO:0036443	biolink:NamedThing	dermatan 6-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate.	got7fsn_ti							bf	2013-10-17T10:41:48Z				KEGG_REACTION:R07288		molecular_function											owl:Class	
GO:0008833	biolink:NamedThing	deoxyribonuclease IV (phage-T4-induced) activity	Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.	got7fsn_ti	E. coli endonuclease IV|deoxyribonuclease IV (phage T4-induced) activity|Escherichia coli endonuclease II|endodeoxyribonuclease IV (phage T(4)-induced) activity|redoxyendonuclease activity|endodeoxyribonuclease IV (phage T4-induced) activity|endonuclease IV activity|deoxriboendonuclease activity|endonuclease II|DNA-adenine-transferase activity											EC:3.1.21.2|MetaCyc:3.1.21.2-RXN		molecular_function											owl:Class	
GO:0090332	biolink:NamedThing	stomatal closure	The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.	got7fsn_ti							tb	2010-05-26T02:14:49Z						biological_process											owl:Class	
GO:0103084	biolink:NamedThing	methylthiobutylmalate dehydrogenase activity	Catalysis of the reaction: 3-(4'-methylthio)butylmalate <=> H+ + 2-oxo-7-methylthioheptanoate + carbon dioxide.	got7fsn_ti												MetaCyc:RXNQT-4168		molecular_function											owl:Class	
GO:0034682	biolink:NamedThing	integrin alphav-beta1 complex	An integrin complex that comprises one alphav subunit and one beta1 subunit.	got7fsn_ti	ITGAV-ITGB1 complex|alphav-beta1 integrin complex													cellular_component											owl:Class	
GO:0046918	biolink:NamedThing	N-terminal peptidyl-glycine N-palmitoylation	The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal glycine residue to form N-palmitoyl-glycine.	got7fsn_ti					Palmitoylation of glycine only occurs when glycine is at the N-terminal position of a protein.							RESID:AA0339		biological_process											owl:Class	
GO:0005758	biolink:NamedThing	mitochondrial intermembrane space	The region between the inner and outer lipid bilayers of the mitochondrial envelope.	got7fsn_ti	mitochondrial membrane lumen|mitochondrial envelope lumen										GO:0031971	NIF_Subcellular:sao118944228		cellular_component											owl:Class	
GO:0004947	biolink:NamedThing	bradykinin receptor activity	Combining with bradykinin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0034675	biolink:NamedThing	integrin alpha6-beta1 complex	An integrin complex that comprises one alpha6 subunit and one beta1 subunit.	got7fsn_ti	VLA-6 complex|alpha6-beta1 integrin complex|ITGA6-ITGB1 complex													cellular_component											owl:Class	
GO:0097029	biolink:NamedThing	mature conventional dendritic cell differentiation	The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.	got7fsn_ti					Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.		pr	2011-04-01T10:10:22Z						biological_process											owl:Class	
GO:0097028	biolink:NamedThing	dendritic cell differentiation	The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.	got7fsn_ti					Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.		pr	2011-04-01T10:08:42Z						biological_process											owl:Class	
GO:0035371	biolink:NamedThing	microtubule plus-end	The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.	got7fsn_ti	microtubule plus end|growing microtubule plus end						bf	2010-03-11T10:55:00Z						cellular_component											owl:Class	
GO:0003060	biolink:NamedThing	negative regulation of the force of heart contraction by acetylcholine	The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction.	got7fsn_ti	decreased force of heart contraction by acetylcholine													biological_process											owl:Class	
GO:0102866	biolink:NamedThing	di-homo-gamma-linolenate delta5 desaturase activity	Catalysis of the reaction: all-cis-icosa-8,11,14-trienoate + O2 + a reduced electron acceptor <=> arachidonate + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												RHEA:46260|MetaCyc:RXN-8346		molecular_function											owl:Class	
GO:0033902	biolink:NamedThing	rRNA endonuclease activity	Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes.	got7fsn_ti	alpha-sarcin											EC:4.6.1.23|MetaCyc:3.1.27.10-RXN		molecular_function											owl:Class	
GO:0010177	biolink:NamedThing	2-(2'-methylthio)ethylmalate synthase activity	Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+.	got7fsn_ti	methylthioalkylmalate synthase activity											MetaCyc:RXN-2202|EC:2.3.3.17		molecular_function											owl:Class	
GO:0016707	biolink:NamedThing	gibberellin 3-beta-dioxygenase activity	Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2.	got7fsn_ti	gibberellin 3beta-hydroxylase activity|(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)|(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)|gibberellin 3-beta-hydroxylase activity|gibberellin 3beta-dioxygenase activity											EC:1.14.11.15|MetaCyc:RXN1F-170|RHEA:10104		molecular_function											owl:Class	
GO:0033556	biolink:NamedThing	dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity	Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol.	got7fsn_ti	dolichyl-P-Glc:Man7GlcNAc2-PP-dolichyl glucosyltransferase activity													molecular_function											owl:Class	
GO:0098875	biolink:NamedThing	epididymosome	A microvesicle of the epididymal fluid, from which spermatozoa aquire membrane proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0034576	biolink:NamedThing	N-isopropylacetanilide amidohydrolase activity	Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate.	got7fsn_ti												UM-BBD_reactionID:r0913		molecular_function											owl:Class	
GO:0033888	biolink:NamedThing	chondro-6-sulfatase activity	Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.	got7fsn_ti	4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity											EC:3.1.6.10|MetaCyc:CHONDRO-6-SULFATASE-RXN|KEGG_REACTION:R03518|RHEA:10536		molecular_function											owl:Class	
GO:0016150	biolink:NamedThing	translation release factor activity, codon nonspecific	A translation release factor that is not specific to particular codons; binds to guanine nucleotides.	got7fsn_ti														molecular_function											owl:Class	
GO:0003885	biolink:NamedThing	D-arabinono-1,4-lactone oxidase activity	Catalysis of the reaction: D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2) + H(+).	got7fsn_ti	D-arabinono-1,4-lactone:oxygen oxidoreductase activity											RHEA:23756|EC:1.1.3.37|KEGG_REACTION:R02715|MetaCyc:1.1.3.37-RXN		molecular_function											owl:Class	
GO:0008788	biolink:NamedThing	alpha,alpha-phosphotrehalase activity	Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate.	got7fsn_ti	trehalose-6-phosphate hydrolase activity|phosphotrehalase activity|alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase activity											EC:3.2.1.93|MetaCyc:TRE6PHYDRO-RXN|RHEA:23008		molecular_function											owl:Class	
GO:0005921	biolink:NamedThing	gap junction	A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins.	got7fsn_ti	macula communicans|zonula communicans|electrical synapse|gap junction macula|electrotonic synapse|gap junction plaque|intercellular gap junction channel|communicating junction											NIF_Subcellular:sao118541872|Wikipedia:Gap_junction		cellular_component											owl:Class	
GO:0075530	biolink:NamedThing	establishment of latency as a linear episome	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure.	got7fsn_ti	establishment of linear plasmid latency|establishment of latency as a linear plasmid						jl	2011-08-04T03:14:23Z						biological_process											owl:Class	
GO:0047214	biolink:NamedThing	cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity	Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP.	got7fsn_ti	UDP-glucose:cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside 5-O-beta-D-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-D-rhamnosyl-1,6-D-glucoside 5-O-D-glucosyltransferase activity|cyanidin-3-O-rutinoside 5-O-glucosyltransferase activity|uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-glucosyltransferase activity											RHEA:12144|MetaCyc:2.4.1.116-RXN|EC:2.4.1.116		molecular_function											owl:Class	
GO:0060941	biolink:NamedThing	epicardium-derived cardiac fibroblast cell fate commitment	The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	got7fsn_ti							dph	2009-09-29T01:44:36Z						biological_process											owl:Class	
GO:0043427	biolink:NamedThing	carbon fixation by 3-hydroxypropionate cycle	An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product.	got7fsn_ti	3-hydroxypropionate pathway|3-hydroxypropionate cycle|hydroxypropionate cycle|hydroxypropionate pathway													biological_process											owl:Class	
GO:0061403	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.	got7fsn_ti							dph	2012-01-10T03:15:30Z						biological_process											owl:Class	
GO:0080108	biolink:NamedThing	S-alkylthiohydroximate lyase activity	Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate.	got7fsn_ti	S-alkylthiohydroximate C-S lyase activity						dhl	2009-04-23T04:35:14Z						molecular_function											owl:Class	
GO:0005731	biolink:NamedThing	nucleolus organizer region	A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed.	got7fsn_ti	NOR|nucleolus organiser region|nucleolus organizer complex											Wikipedia:Nucleolus_organizer_region		cellular_component											owl:Class	
GO:0044694	biolink:NamedThing	pore-mediated entry of viral genome into host cell	Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail.	got7fsn_ti	viral entry via genome injection|viral genome translocation|viral genome delivery via icosahedral vertex|viral pore-forming protein|pore-mediated penetration of viral genome into host cell|membrane puncture-mediated penetration of viral genome into host cell				This mechanism is used by animal viruses such as poliovirus. Various tailed bacteriophages also carry specialized proteins which open a pore or a channel in the host membrane(s) to allow genome delivery into host cytoplasm.		jl	2012-08-16T11:08:02Z				VZ:979		biological_process											owl:Class	
GO:0002782	biolink:NamedThing	antifungal peptide secretion	The regulated release of an antifungal peptide from a cell or a tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0097396	biolink:NamedThing	response to interleukin-17	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.	got7fsn_ti	response to IL-17						pr	2012-10-23T13:22:28Z						biological_process											owl:Class	
GO:1990306	biolink:NamedThing	RSP5-BUL ubiquitin ligase complex	A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation.	got7fsn_ti	RSP5-BUL1 complex|RSP5-BUL2 complex				This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:9931424		bhm	2014-03-03T22:53:01Z						cellular_component											owl:Class	
GO:0097748	biolink:NamedThing	3'-5' RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end.	got7fsn_ti							pr	2016-12-02T11:51:31Z				RHEA:57528		molecular_function											owl:Class	
GO:0009151	biolink:NamedThing	purine deoxyribonucleotide metabolic process	The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine deoxyribonucleotide metabolism													biological_process											owl:Class	
GO:0001729	biolink:NamedThing	ceramide kinase activity	Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.	got7fsn_ti	ATP:ceramide 1-phosphotransferase activity|acylsphingosine kinase activity											EC:2.7.1.138|RHEA:17929|MetaCyc:CERAMIDE-KINASE-RXN|Reactome:R-HSA-1638845		molecular_function											owl:Class	
GO:0006188	biolink:NamedThing	IMP biosynthetic process	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate.	got7fsn_ti	IMP biosynthesis|IMP formation|IMP synthesis|IMP anabolism													biological_process											owl:Class	
GO:0010742	biolink:NamedThing	macrophage derived foam cell differentiation	The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	got7fsn_ti														biological_process											owl:Class	
GO:0043740	biolink:NamedThing	GTP cyclohydrolase IIa activity	Catalysis of the reaction: GTP + 3 H(2)O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H(+) + 2 phosphate.	got7fsn_ti	GTP cyclohydrolase III activity|GTP 8,9-dihydrolase (phosphate-forming)|GTP 8,9-hydrolase (phosphate-forming)											RHEA:22468|MetaCyc:RXN-10055|EC:3.5.4.29|KEGG_REACTION:R07306		molecular_function											owl:Class	
GO:0061590	biolink:NamedThing	calcium activated phosphatidylcholine scrambling	The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.	got7fsn_ti							dph	2014-02-05T15:23:03Z						biological_process											owl:Class	
GO:0008750	biolink:NamedThing	NAD(P)+ transhydrogenase (AB-specific) activity	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+.	got7fsn_ti	pyridine nucleotide transhydrogenase activity|transhydrogenase activity|NAD(P) transhydrogenase (AB-specific) activity|NADPH:NAD+ oxidoreductase (AB-specific)											MetaCyc:1.6.1.2-RXN|EC:1.6.1.2		molecular_function											owl:Class	
GO:0043784	biolink:NamedThing	cob(II)yrinic acid a,c-diamide reductase activity	Catalysis of the reaction: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) = 2 cob(II)yrinate a,c diamide + FMNH(2).	got7fsn_ti	cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity											RHEA:24300|EC:1.16.8.1|KEGG_REACTION:R05218|MetaCyc:R343-RXN		molecular_function											owl:Class	
GO:0097086	biolink:NamedThing	amniotic stem cell differentiation	The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone.	got7fsn_ti							pr	2011-06-22T11:17:52Z						biological_process											owl:Class	
GO:0031840	biolink:NamedThing	type 2 neuromedin U receptor binding	Binding to a type 2 neuromedin U receptor.	got7fsn_ti	type 2 neuromedin U receptor ligand													molecular_function											owl:Class	
GO:0003843	biolink:NamedThing	1,3-beta-D-glucan synthase activity	Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1).	got7fsn_ti	UDP-glucose-beta-glucan glucosyltransferase activity|(1,3)-beta-glucan (callose) synthase activity|1,3-beta-D-glucan synthetase activity|1,3-beta-glucan synthase activity|beta-1,3-glucan synthetase activity|callose synthetase activity|1,3-beta-D-glucan-UDP glucosyltransferase activity|1,3-beta-glucan-uridine diphosphoglucosyltransferase activity|UDPglucose-1,3-beta-D-glucan glucosyltransferase activity|UDP-glucose:(1,3)beta-glucan synthase activity|UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity|beta-1,3-glucan synthase activity|uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase activity|paramylon synthetase|GS-II|UDP-glucose-1,3-beta-D-glucan glucosyltransferase activity|UDP-glucose-1,3-beta-glucan glucosyltransferase activity|callose synthase activity|UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity										GO:0009981	EC:2.4.1.34|RHEA:21476|MetaCyc:13-BETA-GLUCAN-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0102844	biolink:NamedThing	1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming)	Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.23|MetaCyc:RXN-8305		molecular_function											owl:Class	
GO:0103072	biolink:NamedThing	straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity	Catalysis of the reaction: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA = formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde.	got7fsn_ti												MetaCyc:RXN66-475		molecular_function											owl:Class	
GO:0032130	biolink:NamedThing	medial membrane band assembly	The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring.	got7fsn_ti	medial membrane band formation													biological_process											owl:Class	
GO:0047130	biolink:NamedThing	saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = 2-oxoglutarate + L-lysine + H(+) + NADPH.	got7fsn_ti	L-lysine-alpha-ketoglutarate reductase activity|lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity										GO:0010010	MetaCyc:1.5.1.8-RXN|RHEA:19373|Reactome:R-HSA-70938|EC:1.5.1.8|KEGG_REACTION:R00716		molecular_function											owl:Class	
GO:1900820	biolink:NamedThing	orlandin catabolic process	The chemical reactions and pathways resulting in the breakdown of orlandin.	got7fsn_ti	orlandin breakdown|orlandin degradation|orlandin catabolism						di	2012-06-04T10:15:17Z						biological_process											owl:Class	
GO:0071760	biolink:NamedThing	IgY immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	got7fsn_ti					Note that an IgY immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgY is found in amphibians, reptiles, and birds.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0018936	biolink:NamedThing	anaerobic nitrilotriacetate metabolic process	The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen.	got7fsn_ti	anaerobic nitrilotriacetate metabolism													biological_process											owl:Class	
GO:0002505	biolink:NamedThing	antigen processing and presentation of polysaccharide antigen via MHC class II	The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.	got7fsn_ti	polysaccharide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0070162	biolink:NamedThing	adiponectin secretion	The regulated release of adiponectin, a protein hormone, by adipose tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0044228	biolink:NamedThing	host cell surface	The external part of the host cell wall and/or host plasma membrane.	got7fsn_ti							jl	2009-12-03T01:49:45Z						cellular_component											owl:Class	
GO:0050481	biolink:NamedThing	mandelate 4-monooxygenase activity	Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.	got7fsn_ti	mandelic acid 4-hydroxylase activity|L-mandelate 4-hydroxylase activity|(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)											EC:1.14.16.6|RHEA:21716|KEGG_REACTION:R03794|MetaCyc:MANDELATE-4-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0050153	biolink:NamedThing	omega-hydroxydecanoate dehydrogenase activity	Catalysis of the reaction: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + H(+) + NADH.	got7fsn_ti	10-hydroxydecanoate:NAD+ 10-oxidoreductase activity|w-hydroxydecanoate dehydrogenase activity											KEGG_REACTION:R03886|MetaCyc:OMEGA-HYDROXYDECANOATE-DEHYDROGENASE-RXN|RHEA:20880|EC:1.1.1.66		molecular_function											owl:Class	
GO:0047382	biolink:NamedThing	methylphosphothioglycerate phosphatase activity	Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H(2)O = S-methyl-1-thio-D-glycerate + phosphate.	got7fsn_ti	S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase activity|methylthiophosphoglycerate phosphatase activity											RHEA:16081|EC:3.1.3.14|MetaCyc:3.1.3.14-RXN|KEGG_REACTION:R04317		molecular_function											owl:Class	
GO:0021738	biolink:NamedThing	fastigial nucleus development	The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0047876	biolink:NamedThing	endoglycosylceramidase activity	Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose.	got7fsn_ti	oligoglycosylglucosylceramide glycohydrolase activity|EGCase activity|endo-glucosylceramidase activity|endoglycoceramidase activity|glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase activity											MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN|RHEA:22288|EC:3.2.1.123		molecular_function											owl:Class	
GO:0047893	biolink:NamedThing	flavonol 3-O-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.	got7fsn_ti	UDP-glucose:flavonol 3-O-glucosyltransferase activity|UDP-glucose:flavonol 3-O-D-glucosyltransferase activity|UDPglucose:flavonol 3-O-D-glucosyltransferase activity|UDPG:flavonoid-3-O-glucosyltransferase activity|UDP-glucose flavonol 3-O-glucosyltransferase activity|uridine diphosphoglucose-flavonol 3-O-glucosyltransferase activity|GTI											MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.91|RHEA:22300		molecular_function											owl:Class	
GO:0102554	biolink:NamedThing	lipoyl synthase activity (acting on 2-oxoglutarate-dehydrogenase E2 protein	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine  + 2 5'-deoxyadenosine + 2 H+ + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier].	got7fsn_ti												MetaCyc:RXN-14959		molecular_function											owl:Class	
GO:0044689	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+.	got7fsn_ti	FO synthase						jl	2012-08-15T14:33:17Z				MetaCyc:RXN-8079|RHEA:27373|EC:2.5.1.147		molecular_function											owl:Class	
GO:0062239	biolink:NamedThing	heterochromatin-nuclear membrane anchor activity	Binding to heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization.	got7fsn_ti	nuclear membrane-heterochromatin anchor activity|heterochromatin-nuclear membrane tether activity|nuclear membrane-heterochromatin tether activity						dph	2020-04-20T18:20:36Z						molecular_function											owl:Class	
GO:0050399	biolink:NamedThing	xanthommatin reductase activity	Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin.	got7fsn_ti	5,12-dihydroxanthommatin:NAD+ oxidoreductase activity											EC:1.3.1.41|RHEA:13417|KEGG_REACTION:R03787|MetaCyc:XANTHOMMATIN-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0097559	biolink:NamedThing	right ventral flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc.	got7fsn_ti	right ventral cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:28:20Z						cellular_component											owl:Class	
GO:0061158	biolink:NamedThing	3'-UTR-mediated mRNA destabilization	An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.	got7fsn_ti							dph	2010-06-22T08:44:39Z						biological_process											owl:Class	
GO:0004853	biolink:NamedThing	uroporphyrinogen decarboxylase activity	Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.	got7fsn_ti	porphyrinogen carboxy-lyase activity|porphyrinogen decarboxylase activity|uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming)|uroporphyrinogen-III carboxy-lyase activity|uroporphyrinogen III decarboxylase activity											Reactome:R-HSA-189425|Reactome:R-HSA-190182|MetaCyc:UROGENDECARBOX-RXN|RHEA:19865|EC:4.1.1.37		molecular_function											owl:Class	
GO:0106352	biolink:NamedThing	aspartate dehydrogenase NADP activity	Catalysis of the reaction: L-aspartate + H2O + NADP+ = oxaloacetate + NH3 + NADPH+ H+.	got7fsn_ti							hjd	2021-01-20T17:40:23Z				RHEA:11784		molecular_function											owl:Class	
GO:0090391	biolink:NamedThing	granum assembly	A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts.	got7fsn_ti	grana formation						tb	2010-12-08T04:25:46Z						biological_process											owl:Class	
GO:0015679	biolink:NamedThing	plasma membrane copper ion transport	The directed movement of copper ions across the plasma membrane.	got7fsn_ti	plasma membrane copper transport													biological_process											owl:Class	
GO:0070071	biolink:NamedThing	proton-transporting two-sector ATPase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0045054	biolink:NamedThing	constitutive secretory pathway	A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space.	got7fsn_ti	constitutive exocytosis													biological_process											owl:Class	
GO:0019265	biolink:NamedThing	glycine biosynthetic process, by transamination of glyoxylate	The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate.	got7fsn_ti	glycine anabolism, by transamination of glyoxylate|glycine formation, by transamination of glyoxylate|glycine synthesis, by transamination of glyoxylate													biological_process											owl:Class	
GO:0007439	biolink:NamedThing	ectodermal digestive tract development	The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm.	got7fsn_ti	ectodermal gut development													biological_process											owl:Class	
GO:0103048	biolink:NamedThing	tRNA m2A37 methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + an adenine37 in tRNA <=> S-adenosyl-L-homocysteine  + L-methionine  + 5'-deoxyadenosine + a 2-methyladenine37 in tRNA.	got7fsn_ti												MetaCyc:RXN0-7007		molecular_function											owl:Class	
GO:0071834	biolink:NamedThing	mating pheromone secretion	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction.	got7fsn_ti	mating-type pheromone secretion						mah	2010-09-09T11:22:35Z						biological_process											owl:Class	
GO:0070156	biolink:NamedThing	mitochondrial phenylalanyl-tRNA aminoacylation	The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0036399	biolink:NamedThing	TCR signalosome assembly	The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome.	got7fsn_ti	LAT signalosome assembly|linker for activation of T cells signalosome assembly						bf	2013-07-18T14:02:53Z						biological_process											owl:Class	
GO:0032098	biolink:NamedThing	regulation of appetite	Any process which modulates appetite, the desire or physical craving for food.	got7fsn_ti	regulation of hunger													biological_process											owl:Class	
GO:0048403	biolink:NamedThing	brain-derived neurotrophic factor binding	Binding to brain-derived neurotrophic factor.	got7fsn_ti	BDNF binding|neurotrophin TRKB receptor activity													molecular_function											owl:Class	
GO:0008983	biolink:NamedThing	protein-glutamate O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.	got7fsn_ti	protein carboxymethylase activity|methyl-accepting chemotaxis protein methyltransferase II|protein O-methyltransferase activity|protein carboxymethyltransferase activity|protein carboxyl-O-methyltransferase activity|methyl-accepting chemotaxis protein O-methyltransferase activity|S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase activity|protein(carboxyl)methyltransferase activity|MCP methyltransferase I|protein carboxylmethyltransferase II|protein carboxyl-methylase activity|protein(aspartate)methyltransferase activity|S-adenosylmethionine-glutamyl methyltransferase activity|MCP methyltransferase II|S-adenosylmethionine:protein-carboxyl O-methyltransferase activity|protein methylase II											RESID:AA0072|MetaCyc:CHER-RXN|RHEA:24452|EC:2.1.1.80		molecular_function											owl:Class	
GO:0002373	biolink:NamedThing	plasmacytoid dendritic cell cytokine production	Any process that contributes to cytokine production by a plasmacytoid dendritic cell.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:1990429	biolink:NamedThing	peroxisomal importomer complex	A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners.	got7fsn_ti	peroxisomal protein import machinery|peroxisomal import pore|Pex14 complex						jl	2014-07-29T14:45:28Z						cellular_component											owl:Class	
GO:0046451	biolink:NamedThing	diaminopimelate metabolic process	The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.	got7fsn_ti	diaminopimelate metabolism													biological_process											owl:Class	
GO:0010491	biolink:NamedThing	UTP:arabinose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0043308	biolink:NamedThing	eosinophil degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil.	got7fsn_ti	eosinophil granule exocytosis													biological_process											owl:Class	
GO:0035479	biolink:NamedThing	angioblast cell migration from lateral mesoderm to midline	The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature.	got7fsn_ti							bf	2010-04-23T10:38:05Z						biological_process											owl:Class	
GO:0097257	biolink:NamedThing	leukotriene B4 12-hydroxy dehydrogenase activity	Catalysis of the reaction: leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+).	got7fsn_ti	leukotriene B4 12-hydroxydehydrogenase activity						pr	2012-03-07T02:07:41Z				RHEA:50608|Reactome:R-HSA-2161567		molecular_function											owl:Class	
GO:0120185	biolink:NamedThing	MBF transcription complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex.	got7fsn_ti	DSC1 transcription factor complex assembly|MBF complex assembly|Mlu1-box binding factor assembly						krc	2018-07-13T23:21:43Z						biological_process											owl:Class	
GO:0047247	biolink:NamedThing	luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity	Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP.	got7fsn_ti	UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity|UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase activity|LDT|UDPglucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity|UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase activity|uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase activity											EC:2.4.1.191|MetaCyc:2.4.1.191-RXN|KEGG_REACTION:R06828|RHEA:22116		molecular_function											owl:Class	
GO:0008980	biolink:NamedThing	propionate kinase activity	Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate.	got7fsn_ti	PduW|propanoate kinase activity|ATP:propanoate phosphotransferase activity|TdcD											EC:2.7.2.15|RHEA:23148		molecular_function											owl:Class	
GO:0106376	biolink:NamedThing	2-hydroxyphytanoyl-CoA lyase activity	Catalysis of the reaction: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA.	got7fsn_ti							hjd	2021-04-16T12:47:53Z				RHEA:25355		molecular_function											owl:Class	
GO:0004125	biolink:NamedThing	L-seryl-tRNASec selenium transferase activity	Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate.	got7fsn_ti	cysteinyl-tRNA(Sec)-selenium transferase activity|L-seryl-tRNA(Ser) selenium transferase activity|L-selenocysteinyl-tRNASec synthase activity|cysteinyl-tRNASec-selenium transferase activity|selenocysteinyl-tRNA(Ser) synthase activity|selenophosphate:L-seryl-tRNASec selenium transferase activity|cysteinyl-tRNA(Ser) selenium transferase activity|cysteinyl-tRNA(Sel)-selenium transferase activity|L-selenocysteinyl-tRNA(Sel) synthase activity|selenocysteine synthase activity|L-selenocysteinyl-tRNASel synthase activity|cysteinyl-tRNASel-selenium transferase activity|L-selenocysteinyl-tRNA(Sec) synthase activity											MetaCyc:2.9.1.1-RXN|RHEA:22728|EC:2.9.1.1		molecular_function											owl:Class	
GO:0047298	biolink:NamedThing	(S)-3-amino-2-methylpropionate transaminase activity	Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate.	got7fsn_ti	(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase activity|beta-aminoisobutyrate-alpha-ketoglutarate transaminase activity|L-3-aminoisobutyrate transaminase activity|(S)-3-amino-2-methylpropionate aminotransferase activity|L-3-aminoisobutyric aminotransferase activity|L-3-aminoisobutyrate aminotransferase activity|beta-aminobutyric transaminase activity|L-AIBAT activity											MetaCyc:2.6.1.22-RXN|RHEA:13993|EC:2.6.1.22|KEGG_REACTION:R04188		molecular_function											owl:Class	
GO:0004106	biolink:NamedThing	chorismate mutase activity	Catalysis of the reaction: chorismate = prephenate.	got7fsn_ti	chorismate pyruvatemutase activity|hydroxyphenylpyruvate synthase activity											RHEA:13897|EC:5.4.99.5|MetaCyc:CHORISMATEMUT-RXN|KEGG_REACTION:R01715		molecular_function											owl:Class	
GO:0033969	biolink:NamedThing	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate.	got7fsn_ti	gamma-glutamyl-GABA hydrolase activity|PuuD|YcjL|4-(glutamylamino)butanoate amidohydrolase activity											KEGG_REACTION:R07419|MetaCyc:RXN0-3942|EC:3.5.1.94|RHEA:19737		molecular_function											owl:Class	
GO:0047556	biolink:NamedThing	3,4-dihydroxyphthalate decarboxylase activity	Catalysis of the reaction: 3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO(2).	got7fsn_ti	3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)|3,4-dihydroxyphthalate carboxy-lyase activity|3,4-dihydroxyphthalate 2-decarboxylase activity										GO:0034913	RHEA:18601|UM-BBD_reactionID:r1447|MetaCyc:34-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN|EC:4.1.1.69|KEGG_REACTION:R01634		molecular_function											owl:Class	
GO:0004775	biolink:NamedThing	succinate-CoA ligase (ADP-forming) activity	Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.	got7fsn_ti	succinyl coenzyme A synthetase|succinic thiokinase|succinyl-CoA synthetase (ADP-forming) activity|succinyl-CoA synthetase activity|succinyl coenzyme A synthetase (adenosine diphosphate-forming) activity|succinate thiokinase activity|A-STK (adenin nucleotide-linked succinate thiokinase)|A-SCS|succinate:CoA ligase (ADP-forming) activity											EC:6.2.1.5|KEGG_REACTION:R00405|MetaCyc:SUCCCOASYN-RXN|Reactome:R-HSA-70997|RHEA:17661		molecular_function											owl:Class	
GO:0050683	biolink:NamedThing	AF-1 domain binding	Binding to an AF-1 protein domain, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0005148	biolink:NamedThing	prolactin receptor binding	Binding to a prolactin receptor.	got7fsn_ti	prolactin receptor ligand|prolactin													molecular_function											owl:Class	
GO:0051885	biolink:NamedThing	positive regulation of timing of anagen	Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.	got7fsn_ti	up-regulation of anagen|stimulation of anagen|up regulation of anagen|positive regulation of anagen|upregulation of anagen|activation of anagen													biological_process											owl:Class	
GO:0051581	biolink:NamedThing	negative regulation of neurotransmitter uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.	got7fsn_ti	negative regulation of neurotransmitter import|down-regulation of neurotransmitter uptake|downregulation of neurotransmitter uptake|down regulation of neurotransmitter uptake													biological_process											owl:Class	
GO:0033867	biolink:NamedThing	Fas-activated serine/threonine kinase activity	Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.	got7fsn_ti	FASTK|ATP:Fas-activated serine/threonine protein phosphotransferase activity|STK10|FAST											EC:2.7.11.8|MetaCyc:2.7.11.8-RXN		molecular_function											owl:Class	
GO:0050088	biolink:NamedThing	mannose-6-phosphate 6-reductase activity	Catalysis of the reaction: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + 3 H(+) + NADPH.	got7fsn_ti	NADPH-dependent mannose 6-phosphate reductase activity|NADPH-mannose-6-P reductase activity|NADPH-dependent M6P reductase activity|NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase activity|mannose-6-phosphate reductase activity|D-mannitol-1-phosphate:NADP+ 6-oxidoreductase activity|6-phosphomannose reductase activity											KEGG_REACTION:R01817|MetaCyc:MANNOSE-6-PHOSPHATE-6-REDUCTASE-RXN|RHEA:14925|EC:1.1.1.224		molecular_function											owl:Class	
GO:0005914	biolink:NamedThing	spot adherens junction	A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens.	got7fsn_ti	punctum adherens|dense plaque													cellular_component											owl:Class	
GO:0072101	biolink:NamedThing	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.	got7fsn_ti	specification of ureteric bud anterior/posterior asymmetry by BMP signaling pathway|specification of ureteric bud anterior/posterior symmetry by BMP signalling pathway						mah	2010-02-10T02:21:03Z						biological_process											owl:Class	
GO:1901719	biolink:NamedThing	regulation of NMS complex assembly	Any process that modulates the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.	got7fsn_ti	regulation of KMN network assembly involved in chromosome segregation|regulation of NMS complex assembly involved in kinetochore assembly|regulation of KMN complex assembly involved in chromosome segregation|regulation of NMS complex association involved in chromosome segregation						jl	2012-12-20T11:44:17Z						biological_process											owl:Class	
GO:0090234	biolink:NamedThing	regulation of kinetochore assembly	Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	got7fsn_ti	regulation of chromosome-kinetochore attachment						tb	2010-01-20T10:46:56Z						biological_process											owl:Class	
GO:0099153	biolink:NamedThing	synaptic transmission, serotonergic	The vesicular release of  serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	got7fsn_ti	serotonergic synaptic transmission						dos	2017-07-05T14:16:51Z						biological_process											owl:Class	
GO:0047109	biolink:NamedThing	(S)-3-hydroxyacid-ester dehydrogenase activity	Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH.	got7fsn_ti	(S)-3-hydroxyacid ester dehydrogenase activity|ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity|3-oxo ester (S)-reductase activity				Note that this term was EC:1.2.1.56.							EC:1.1.1.280|KEGG_REACTION:R04106|MetaCyc:1.2.1.56-RXN|RHEA:18269		molecular_function											owl:Class	
GO:0051396	biolink:NamedThing	positive regulation of nerve growth factor receptor activity	Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.	got7fsn_ti	stimulation of nerve growth factor receptor activity|up-regulation of nerve growth factor receptor activity|activation of nerve growth factor receptor activity|positive regulation of NGF receptor activity|up regulation of nerve growth factor receptor activity|upregulation of nerve growth factor receptor activity													biological_process											owl:Class	
GO:0050567	biolink:NamedThing	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.	got7fsn_ti	glutaminyl-tRNA synthase (glutamine-hydrolysing)|glutamyl-tRNA(Gln) amidotransferase activity|Glu-tRNA(Gln) amidotransferase activity|Glu-AdT activity|glutamyl-tRNAGln:L-glutamine amido-ligase (ADP-forming)|Glu-tRNAGln:L-glutamine amido-ligase (ADP-forming)|glutamyl-tRNAGln amidotransferase activity|Glu-tRNAGln amidotransferase activity										GO:0008264|GO:0017068	MetaCyc:6.3.5.7-RXN|RHEA:17521|Wikipedia:Glutaminyl-tRNA_synthase_(glutamine-hydrolysing)|EC:6.3.5.7		molecular_function											owl:Class	
GO:0001869	biolink:NamedThing	negative regulation of complement activation, lectin pathway	Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.	got7fsn_ti	negative regulation of complement cascade, lectin pathway|down regulation of complement activation, lectin pathway|down-regulation of complement activation, lectin pathway|downregulation of complement activation, lectin pathway|inhibition of complement activation, lectin pathway													biological_process											owl:Class	
GO:0004155	biolink:NamedThing	6,7-dihydropteridine reductase activity	Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine.	got7fsn_ti	dihydropteridine reduction|6,7-dihydropteridine:NAD(P)H oxidoreductase activity|5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity|NADH-dihydropteridine reductase activity|NADPH-specific dihydropteridine reductase activity|NAD(P)H2:6,7-dihydropteridine oxidoreductase activity|dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity|dihydropteridine reductase (NADH) activity|dihydropteridine reductase activity|NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity|5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity|DHPR activity|NADPH-dihydropteridine reductase activity				Note that this function was formerly EC:1.6.99.7.							MetaCyc:1.5.1.34-RXN|Reactome:R-HSA-71130|EC:1.5.1.34		molecular_function											owl:Class	
GO:0004401	biolink:NamedThing	histidinol-phosphatase activity	Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate.	got7fsn_ti	L-histidinol phosphate phosphatase activity|histidinolphosphate phosphatase activity|histidinolphosphatase activity|HPpase activity|L-histidinol-phosphate phosphohydrolase activity|histidinol phosphate phosphatase activity											MetaCyc:HISTIDPHOS-RXN|KEGG_REACTION:R03013|EC:3.1.3.15|RHEA:14465		molecular_function											owl:Class	
GO:0052168	biolink:NamedThing	modulation by symbiont of defense-related host calcium-dependent protein kinase pathway	Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction|modulation by organism of defense-related host CDPK pathway										GO:0052307			biological_process											owl:Class	
GO:0008446	biolink:NamedThing	GDP-mannose 4,6-dehydratase activity	Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O.	got7fsn_ti	GDP-mannose 4,6-hydro-lyase activity|guanosine 5'-diphosphate-D-mannose oxidoreductase activity|GDP-D-mannose dehydratase activity|guanosine diphosphomannose 4,6-dehydratase activity|GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)|GDPmannose 4,6-dehydratase activity|Gmd|guanosine diphosphomannose oxidoreductase activity|GDP-D-mannose 4,6-dehydratase activity											EC:4.2.1.47|MetaCyc:GDPMANDEHYDRA-RXN|RHEA:23820|KEGG_REACTION:R00888|Reactome:R-HSA-6787632		molecular_function											owl:Class	
GO:0032626	biolink:NamedThing	interleukin-22 production	The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	ZCYTO18 production|ILTIF production|IL-22 production|IL22 production|interleukin-22 secretion|interleukin-22 biosynthetic process										GO:0042239|GO:0072620			biological_process											owl:Class	
GO:0004118	biolink:NamedThing	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.	got7fsn_ti														molecular_function											owl:Class	
GO:0031768	biolink:NamedThing	ghrelin receptor binding	Binding to a ghrelin receptor.	got7fsn_ti	ghrelin receptor ligand|type 1 growth hormone secretagogue GH-releasing peptide receptor binding													molecular_function											owl:Class	
GO:1990599	biolink:NamedThing	3' overhang single-stranded DNA endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks.	got7fsn_ti							al	2015-01-06T15:21:28Z						molecular_function											owl:Class	
GO:0000014	biolink:NamedThing	single-stranded DNA endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.	got7fsn_ti	ssDNA-specific endodeoxyribonuclease activity|single-stranded DNA specific endodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0050596	biolink:NamedThing	vinorine hydroxylase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + vinorine = H(2)O + NADP(+) + vomilenine.	got7fsn_ti	vinorine,NADPH:oxygen oxidoreductase (21alpha-hydroxylating)											MetaCyc:1.14.13.75-RXN|EC:1.14.14.104|RHEA:17257|KEGG_REACTION:R05877		molecular_function											owl:Class	
GO:0018739	biolink:NamedThing	4-hydroxybenzoyl-CoA thioesterase activity	Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA + H(+).	got7fsn_ti	4-hydroxybenzoyl-CoA hydrolase activity|4-hydroxybenzoyl-CoA thiolesterase activity											KEGG_REACTION:R01301|UM-BBD_reactionID:r0141|MetaCyc:3.1.2.23-RXN|RHEA:11948|EC:3.1.2.23		molecular_function											owl:Class	
GO:0047954	biolink:NamedThing	glycerol-2-phosphatase activity	Catalysis of the reaction: glycerol 2-phosphate + H(2)O = glycerol + phosphate.	got7fsn_ti	glycerol-2-phosphate phosphohydrolase activity|beta-glycerophosphate phosphatase activity|beta-glycerophosphatase activity|2-glycerophosphatase activity											EC:3.1.3.19|MetaCyc:GLYCEROL-2-PHOSPHATASE-RXN|KEGG_REACTION:R01043|RHEA:13105		molecular_function											owl:Class	
GO:0052909	biolink:NamedThing	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA.	got7fsn_ti	M(6)(2)A dimethylase activity	https://github.com/geneontology/go-ontology/issues/14459										EC:2.1.1.183|MetaCyc:RXN-11634|RHEA:42780		molecular_function											owl:Class	
GO:0140032	biolink:NamedThing	glycosylation-dependent protein binding	Binding to a protein upon glycosylation of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require glycosylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of glycosylation. It may be that the glycosylation causes a conformational change that allows binding of the protein to another region; this type of glycosylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T15:20:50Z						molecular_function											owl:Class	
GO:0033458	biolink:NamedThing	GAC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GAC codon.	got7fsn_ti	aspartic acid tRNA				Note that in the standard genetic code, GAC codes for aspartic acid.									molecular_function											owl:Class	
GO:0008114	biolink:NamedThing	phosphogluconate 2-dehydrogenase activity	Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH.	got7fsn_ti	6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase activity|6-phosphogluconate dehydrogenase (NAD)|6-phosphogluconate 2-dehydrogenase activity|2-keto-6-phosphogluconate reductase activity|phosphogluconate dehydrogenase activity|gluconate 6-phosphate dehydrogenase activity|6-phosphogluconic dehydrogenase activity											MetaCyc:1.1.1.43-RXN|EC:1.1.1.43		molecular_function											owl:Class	
GO:0047343	biolink:NamedThing	glucose-1-phosphate cytidylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate.	got7fsn_ti	CTP:alpha-D-glucose-1-phosphate cytidylyltransferase activity|CDP glucose pyrophosphorylase activity|CDP-glucose diphosphorylase activity|CTP:glucose-1-phosphate cytidylyltransferase activity|CTP:D-glucose-1-phosphate cytidylyltransferase activity|CDP-glucose pyrophosphorylase activity|cytidine diphosphoglucose pyrophosphorylase activity|cytidine diphosphate-D-glucose pyrophosphorylase activity|cytidine diphosphate glucose pyrophosphorylase activity											MetaCyc:2.7.7.33-RXN|EC:2.7.7.33|KEGG_REACTION:R00956|RHEA:18213		molecular_function											owl:Class	
GO:0010814	biolink:NamedThing	substance P catabolic process	The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P.	got7fsn_ti														biological_process											owl:Class	
GO:0018675	biolink:NamedThing	(S)-limonene 6-monooxygenase activity	Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O.	got7fsn_ti	limonene 6-hydroxylase activity|(-)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity|(-)-limonene 6-hydroxylase activity|(S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating)|(-)-limonene 6-monooxygenase activity											UM-BBD_reactionID:r0713|EC:1.14.14.51|RHEA:17945|MetaCyc:--LIMONENE-6-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0015608	biolink:NamedThing	carbohydrate-importing ABC transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).	got7fsn_ti	sugar transporter|carbohydrate uptake transporter activity|carbohydrate-importing ATPase activity	https://github.com/geneontology/go-ontology/issues/17289										TC:3.A.1.1.1		molecular_function											owl:Class	
GO:0070561	biolink:NamedThing	vitamin D receptor signaling pathway	The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.	got7fsn_ti	VDR signaling pathway|calcitriol signaling pathway|vitamin D receptor signalling pathway						mah	2009-04-14T01:43:59Z						biological_process											owl:Class	
GO:0052621	biolink:NamedThing	diguanylate cyclase activity	Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+).	got7fsn_ti	GTP:GTP guanylyltransferase activity										GO:0043789	EC:2.7.7.65|RHEA:24898|MetaCyc:RXN0-5359|KEGG_REACTION:R08057		molecular_function											owl:Class	
GO:0051654	biolink:NamedThing	establishment of mitochondrion localization	The directed movement of the mitochondrion to a specific location.	got7fsn_ti	establishment of mitochondrion localisation|establishment of mitochondria localization|mitochondrial migration|mitochondria positioning|mitochondrion positioning													biological_process											owl:Class	
GO:0000474	biolink:NamedThing	maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	got7fsn_ti														biological_process											owl:Class	
GO:0140421	biolink:NamedThing	endocytic heme import into cell	The directed movement into cell of externally available heme by receptor-mediated endocytosis.	got7fsn_ti	heme assimilation	https://github.com/geneontology/go-ontology/issues/18671					pg	2020-01-30T13:14:02Z						biological_process											owl:Class	
GO:0098657	biolink:NamedThing	import into cell	The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.	got7fsn_ti	uptake													biological_process											owl:Class	
GO:0022859	biolink:NamedThing	dephosphorylation-gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0061328	biolink:NamedThing	posterior Malpighian tubule development	The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.	got7fsn_ti							dph	2010-09-28T01:24:35Z						biological_process											owl:Class	
GO:1990114	biolink:NamedThing	RNA polymerase II core complex assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.	got7fsn_ti	RNA Polymerase II assembly|DNA-directed RNA polymerase II, core complex assembly						rb	2013-05-31T21:46:42Z						biological_process											owl:Class	
GO:0046653	biolink:NamedThing	tetrahydrofolate metabolic process	The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.	got7fsn_ti	tetrahydrofolate metabolism													biological_process											owl:Class	
GO:0061172	biolink:NamedThing	regulation of establishment of bipolar cell polarity	Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.	got7fsn_ti							dph	2010-06-30T08:51:27Z						biological_process											owl:Class	
GO:0034892	biolink:NamedThing	endosulfan lactone lactonase activity	Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+.	got7fsn_ti												UM-BBD_reactionID:r1389		molecular_function											owl:Class	
GO:0030763	biolink:NamedThing	isobutyraldoxime O-methyltransferase activity	Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosylmethionine:aldoxime O-methyltransferase activity|aldoxime methyltransferase activity|aldoxime O-methyltransferase activity|S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase activity											RHEA:10996|EC:2.1.1.91|KEGG_REACTION:R04169|MetaCyc:ISOBUTYRALDOXIME-O-METHYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0034568	biolink:NamedThing	isoproturon dimethylaminedehydrogenase activity	Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-.	got7fsn_ti												EC:1.5.99.-|UM-BBD_reactionID:r0892		molecular_function											owl:Class	
GO:0050081	biolink:NamedThing	maltose-6'-phosphate glucosidase activity	Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate.	got7fsn_ti	phospho-alpha-glucosidase activity|maltose-6'-phosphate 6-phosphoglucohydrolase activity											EC:3.2.1.122|MetaCyc:MALTOSE-6-PHOSPHATE-GLUCOSIDASE-RXN|RHEA:20421		molecular_function											owl:Class	
GO:0030603	biolink:NamedThing	oxaloacetase activity	Catalysis of the reaction: H(2)O + oxaloacetate = acetate + H(+) + oxalate.	got7fsn_ti	oxaloacetate acetylhydrolase activity|oxalacetic hydrolase activity											MetaCyc:OXALOACETASE-RXN|EC:3.7.1.1|RHEA:24432|KEGG_REACTION:R00338		molecular_function											owl:Class	
GO:0035818	biolink:NamedThing	positive regulation of urine volume by pressure natriuresis	An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis.	got7fsn_ti	diuresis resulting from pressure natriuresis						bf	2011-04-20T01:55:42Z						biological_process											owl:Class	
GO:0102895	biolink:NamedThing	colneleate synthase activity	Catalysis of the reaction: 9(S)-HPODE <=> colneleate + H2O.	got7fsn_ti												MetaCyc:RXN-8496|EC:4.2.1.121|RHEA:28174		molecular_function											owl:Class	
GO:0090415	biolink:NamedThing	7-hydroxymethyl chlorophyll a reductase activity	Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O.	got7fsn_ti							tb	2011-10-03T12:08:27Z						molecular_function											owl:Class	
GO:0052592	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	got7fsn_ti	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulphur protein as acceptor											EC:1.17.7.-		molecular_function											owl:Class	
GO:0044220	biolink:NamedThing	host cell perinuclear region of cytoplasm	The host cell cytoplasm situated near, or occurring around, the host nucleus.	got7fsn_ti							jl	2009-11-12T02:58:13Z						cellular_component											owl:Class	
GO:0015046	biolink:NamedThing	rubredoxin-NADP+ reductase activity	Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+.	got7fsn_ti												EC:1.18.1.4|RHEA:13949		molecular_function											owl:Class	
GO:0006855	biolink:NamedThing	xenobiotic transmembrane transport	The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	drug transmembrane transport|multidrug transport|drug membrane transport	https://github.com/geneontology/go-ontology/issues/19460			Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:0034978	biolink:NamedThing	PDX1-PBX1b-MRG1 complex	A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes.	got7fsn_ti	acinar cell-specific C complex													cellular_component											owl:Class	
GO:0047255	biolink:NamedThing	galactogen 6-beta-galactosyltransferase activity	Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP.	got7fsn_ti	galactogen 6beta-galactosyltransferase activity|uridine diphosphogalactose-galactogen galactosyltransferase activity|1,6-D-galactosyltransferase activity|beta-(1,6)-D-galactosyltransferase activity|UDP-galactose:galactogen beta-1,6-D-galactosyltransferase activity|UDPgalactose:galactogen beta-1,6-D-galactosyltransferase activity											EC:2.4.1.205|MetaCyc:2.4.1.205-RXN		molecular_function											owl:Class	
GO:1900811	biolink:NamedThing	helvolic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of helvolic acid.	got7fsn_ti	Fumigacin degradation|helvolic acid breakdown|Fumigacin catabolism|helvolic acid catabolism|Fumigacin catabolic process|Fumigacin breakdown|helvolic acid degradation						di	2012-06-04T10:02:51Z						biological_process											owl:Class	
GO:0000334	biolink:NamedThing	3-hydroxyanthranilate 3,4-dioxygenase activity	Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).	got7fsn_ti	3HAO|3-hydroxyanthranilate oxygenase activity|3-hydroxyanthranilic acid oxygenase activity|3-hydroxyanthranilic acid dioxygenase activity|3-hydroxyanthranilic oxygenase activity|3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)											EC:1.13.11.6|KEGG_REACTION:R02665|RHEA:17953|UM-BBD_reactionID:r1027|MetaCyc:1.13.11.6-RXN|Reactome:R-HSA-71218		molecular_function											owl:Class	
GO:0031741	biolink:NamedThing	type B gastrin/cholecystokinin receptor binding	Binding to a type B gastrin/cholecystokinin receptor.	got7fsn_ti	type B gastrin/cholecystokinin receptor ligand													molecular_function											owl:Class	
GO:1990956	biolink:NamedThing	fibroblast chemotaxis	The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	got7fsn_ti							dph	2016-06-02T19:54:19Z						biological_process											owl:Class	
GO:0010031	biolink:NamedThing	circumnutation	The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth.	got7fsn_ti														biological_process											owl:Class	
GO:0036006	biolink:NamedThing	cellular response to macrophage colony-stimulating factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.	got7fsn_ti	cellular response to M-CSF stimulus|cellular response to macrophage colony-stimulating factor						bf	2011-09-20T04:23:19Z						biological_process											owl:Class	
GO:0070817	biolink:NamedThing	P-TEFb-cap methyltransferase complex localization	Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.	got7fsn_ti	P-TEFb-cap methyltransferase complex localisation|establishment and maintenance of P-TEFb-cap methyltransferase complex localization						mah	2009-07-13T04:20:17Z						biological_process											owl:Class	
GO:0005278	biolink:NamedThing	acetylcholine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out).	got7fsn_ti	acetylcholine:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0052773	biolink:NamedThing	diacetylchitobiose deacetylase activity	Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc).	got7fsn_ti	N,N'-diacetylchitobiose deacetylase (nonreducing end)				In this reaction N,N'-diacetylchitobiose is deacetylated at the non-reducing residue to produce 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc). This is in contrast to EC:3.5.1.105 in which N,N'-diacetylchitobiose is deacetylated at the reducing residue to produce 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine (GlcNAc-GlcN). For the latter reaction, see GO:0036311.		ai	2011-10-03T12:01:05Z				MetaCyc:RXN-12543		molecular_function											owl:Class	
GO:0035230	biolink:NamedThing	cytoneme	A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um.	got7fsn_ti	membrane nanotube											Wikipedia:Membrane_nanotube		cellular_component											owl:Class	
GO:0018762	biolink:NamedThing	aliphatic nitrilase activity	Catalysis of the reaction: R-CN + H2O = R-COOH + NH3.	got7fsn_ti	aliphatic nitrile aminohydrolase activity											RHEA:46188|UM-BBD_reactionID:r0622|EC:3.5.5.7|MetaCyc:3.5.5.7-RXN		molecular_function											owl:Class	
GO:2001031	biolink:NamedThing	positive regulation of cellular glucuronidation	Any process that activates or increases the frequency, rate or extent of cellular glucuronidation.	got7fsn_ti	positive regulation of cellular glucuronoside biosynthesis|positive regulation of cellular glucuronoside biosynthetic process|positive regulation of cellular glucuronide biosynthesis|positive regulation of cellular glucuronide biosynthetic process						rl	2011-08-22T01:10:59Z						biological_process											owl:Class	
GO:0102334	biolink:NamedThing	N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity	Catalysis of the reaction: ditrans,polycis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine <=> N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UMP.	got7fsn_ti												MetaCyc:RXN-13269|RHEA:34515|EC:2.7.8.36		molecular_function											owl:Class	
GO:0140701	biolink:NamedThing	3',3'-cyclic GMP-AMP synthase activity	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(3'-5') (cyclic 3',3' GAMP).	got7fsn_ti	3',3'-cyclic GAMP synthase activity|3',3' cyclic-GMP-AMP synthase activity|3',3' cyclic-GAMP synthase activity	https://github.com/geneontology/go-ontology/issues/21980					pg	2021-08-27T05:13:09Z				RHEA:35647		molecular_function											owl:Class	
GO:0042163	biolink:NamedThing	interleukin-12 beta subunit binding	Binding to the beta subunit of interleukin-12.	got7fsn_ti	NKSFp40 binding|IL-12B binding|CLMFp40 binding|IL-12p40 binding													molecular_function											owl:Class	
GO:0090038	biolink:NamedThing	negative regulation of protein kinase C signaling	Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	negative regulation of protein kinase C signaling cascade|negative regulation of protein kinase C signalling cascade						tb	2009-08-03T11:29:33Z						biological_process											owl:Class	
GO:0102465	biolink:NamedThing	zeaxanthin 2,2'-beta-hydroxylase activity	Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 <=> nostoxanthin + 2 NAD + 2 H2O.	got7fsn_ti												MetaCyc:RXN-14018		molecular_function											owl:Class	
GO:0050406	biolink:NamedThing	[acetyl-CoA carboxylase]-phosphatase activity	Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate.	got7fsn_ti	acetyl-CoA:carbon-dioxide ligase (ADP-forming)-phosphate phosphohydrolase activity|acetyl-CoA carboxylase-phosphatase activity											RHEA:17125|EC:3.1.3.44|MetaCyc:ACETYL-COA-CARBOXYLASE-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0140595	biolink:NamedThing	MIM complex	A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. MIM constitutes the major integration site for alpha-helical embedded proteins. In yeast, consists oof Mim1 and Mim2.	got7fsn_ti	mitochondrial outer import machinery	https://github.com/geneontology/go-ontology/issues/20669					pg	2021-02-09T19:34:16Z						cellular_component											owl:Class	
GO:0090268	biolink:NamedThing	activation of mitotic cell cycle spindle assembly checkpoint	Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint.	got7fsn_ti							tb	2010-02-05T02:09:44Z						biological_process											owl:Class	
GO:0034102	biolink:NamedThing	erythrocyte clearance	The selective elimination of erythrocytes from the body by autoregulatory mechanisms.	got7fsn_ti	neocytolysis|red blood cell clearance|RBC clearance				Note that this term is intended for annotation of self-gene products that lead to elimination of erythrocytes without the involvement of a symbiont.									biological_process											owl:Class	
GO:0102356	biolink:NamedThing	isoitalicene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene.	got7fsn_ti												MetaCyc:RXN-13373		molecular_function											owl:Class	
GO:0031040	biolink:NamedThing	micronucleus	A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell.	got7fsn_ti												Wikipedia:Micronucleus		cellular_component											owl:Class	
GO:0052079	biolink:NamedThing	induction by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	Any process in which an organism activates, maintains or increases the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	upregulation by organism of defense-related host MAP kinase-mediated signal transduction pathway|activation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|induction by organism of defense-related host MAP kinase-mediated signal transduction pathway|upregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|stimulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|activation by organism of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|up regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway|positive regulation by organism of defense-related host MAPK-mediated signal transduction pathway|up-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	https://github.com/geneontology/go-ontology/issues/19235									GO:0052276			biological_process											owl:Class	
GO:0003064	biolink:NamedThing	regulation of heart rate by hormone	The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.	got7fsn_ti	hormonal cardiac chronotropy|regulation of the rate of heart contraction by hormone													biological_process											owl:Class	
GO:0072058	biolink:NamedThing	outer stripe development	The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.	got7fsn_ti							mah	2010-01-25T04:02:56Z						biological_process											owl:Class	
GO:0032207	biolink:NamedThing	regulation of telomere maintenance via recombination	Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.	got7fsn_ti														biological_process											owl:Class	
GO:0032108	biolink:NamedThing	negative regulation of response to nutrient levels	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.	got7fsn_ti	downregulation of response to nutrient levels|down-regulation of response to nutrient levels|down regulation of response to nutrient levels|inhibition of response to nutrient levels													biological_process											owl:Class	
GO:0070621	biolink:NamedThing	EGFR-Shc-Grb2-Sos complex	A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.	got7fsn_ti							mah	2009-04-29T04:38:10Z						cellular_component											owl:Class	
GO:0102799	biolink:NamedThing	glucosinolate glucohydrolase activity	Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate.  Glucosinolates are a subclass of thioglucosides.	got7fsn_ti												EC:3.2.1.147|MetaCyc:RXN-8134		molecular_function											owl:Class	
GO:0050640	biolink:NamedThing	isopenicillin-N N-acyltransferase activity	Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate.	got7fsn_ti	acyl-CoA:isopenicillin N N-acyltransferase activity|acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase activity|isopenicillin N:acyl-CoA acyltransferase activity|isopenicillin-N acyltransferase activity|acyl-coenzyme A:isopenicillin N acyltransferase activity										GO:0045440|GO:0042319	RHEA:20720|EC:2.3.1.164|MetaCyc:2.3.1.164-RXN		molecular_function											owl:Class	
GO:0046680	biolink:NamedThing	response to DDT	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.	got7fsn_ti	DDT resistance|DDT susceptibility/resistance													biological_process											owl:Class	
GO:0071492	biolink:NamedThing	cellular response to UV-A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.	got7fsn_ti	cellular response to UV-A light stimulus|cellular response to UVA light stimulus|cellular response to UV-A radiation stimulus|cellular response to UVA radiation stimulus						mah	2009-12-18T02:21:51Z						biological_process											owl:Class	
GO:0001694	biolink:NamedThing	histamine biosynthetic process	The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	got7fsn_ti	histamine synthesis|histamine biosynthesis|histamine anabolism|histamine formation										GO:0001693			biological_process											owl:Class	
GO:0047594	biolink:NamedThing	6-beta-hydroxyhyoscyamine epoxidase activity	Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O(2) = CO(2) + H(2)O + H(+) + scopolamine + succinate.	got7fsn_ti	(6S)-6-hydroxyhyoscyamine,2-oxoglutarate oxidoreductase (epoxide-forming)|hydroxyhyoscyamine dioxygenase activity|6beta-hydroxyhyoscyamine epoxidase activity											MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN|RHEA:12797|KEGG_REACTION:R03737|EC:1.14.20.13		molecular_function											owl:Class	
GO:0014830	biolink:NamedThing	arteriole smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.	got7fsn_ti														biological_process											owl:Class	
GO:0004046	biolink:NamedThing	aminoacylase activity	Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.	got7fsn_ti	N-acyl-L-amino-acid amidohydrolase activity|benzamidase activity|L-amino-acid acylase activity|short acyl amidoacylase activity|hippurase activity|L-aminoacylase activity|histozyme activity|aminoacylase I activity|dehydropeptidase II activity|amido acid deacylase activity|acylase I activity|long acyl amidoacylase activity|alpha-N-acylaminoacid hydrolase activity											RHEA:15565|Reactome:R-HSA-9638046|EC:3.5.1.14|Reactome:R-HSA-5433074|MetaCyc:AMINOACYLASE-RXN|Reactome:R-HSA-5579081		molecular_function											owl:Class	
GO:0048189	biolink:NamedThing	Lid2 complex	A protein complex involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid2, Ash2, Jmj3, Snt2, and Sdc1.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22010												cellular_component											owl:Class	
GO:0097099	biolink:NamedThing	structural constituent of albumen	The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo.	got7fsn_ti	structural constituent of egg white						pr	2011-07-07T02:12:51Z						molecular_function											owl:Class	
GO:0042398	biolink:NamedThing	cellular modified amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.	got7fsn_ti	cellular amino acid derivative anabolism|cellular amino acid derivative synthesis|cellular modified amino acid formation|cellular modified amino acid anabolism|cellular modified amino acid synthesis|cellular amino acid derivative biosynthesis|cellular amino acid derivative formation|cellular modified amino acid biosynthesis|amino acid derivative biosynthetic process|cellular amino acid derivative biosynthetic process													biological_process											owl:Class	
GO:0004485	biolink:NamedThing	methylcrotonoyl-CoA carboxylase activity	Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H(+) + phosphate.	got7fsn_ti	MCCC activity|beta-methylcrotonyl-CoA carboxylase activity|beta-methylcrotonyl coenzyme A carboxylase activity|beta-methylcrotonyl CoA carboxylase activity|3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)|methylcrotonyl-CoA carboxylase activity|methylcrotonyl coenzyme A carboxylase activity											EC:6.4.1.4|MetaCyc:METHYLCROTONYL-COA-CARBOXYLASE-RXN|KEGG_REACTION:R04138|RHEA:13589|Reactome:R-HSA-508308|Reactome:R-HSA-70773		molecular_function											owl:Class	
GO:0046842	biolink:NamedThing	trisporic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of trisporic acid.	got7fsn_ti	trisporic acid synthesis|trisporic acid formation|trisporic acid anabolism|trisporic acid biosynthesis													biological_process											owl:Class	
GO:0009519	biolink:NamedThing	middle lamella	Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells.	got7fsn_ti												Wikipedia:Middle_lamella		cellular_component											owl:Class	
GO:0103089	biolink:NamedThing	methylthiohexylmalate isomerase activity	Catalysis of the reaction: 2-(6'-methylthio)hexylmalate <=> 3-(6'-methylthio)hexylmalate.	got7fsn_ti												MetaCyc:RXNQT-4173		molecular_function											owl:Class	
GO:0034792	biolink:NamedThing	hypophosphite dioxygenase activity	Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2.	got7fsn_ti												UM-BBD_reactionID:r1058		molecular_function											owl:Class	
GO:0047627	biolink:NamedThing	adenylylsulfatase activity	Catalysis of the reaction: 5'-adenylyl sulfate + H(2)O = AMP + 2 H(+) + sulfate.	got7fsn_ti	adenosine 5-phosphosulfate sulfohydrolase activity|adenylylsulfate sulfohydrolase activity|adenylylsulphatase activity											MetaCyc:ADENYLYLSULFATASE-RXN|EC:3.6.2.1|RHEA:17041|KEGG_REACTION:R00531		molecular_function											owl:Class	
GO:0052911	biolink:NamedThing	23S rRNA (guanine(745)-N(1))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine.	got7fsn_ti	S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity|rRNA(m(1)G)methylase activity|ribosomal RNA(m(1)G)-methylase activity|23S rRNA m(1)G(745) methyltransferase activity|ribosomal ribonucleate guanine 1-methyltransferase activity|rlmA(I) methyltransferase activity											RHEA:42900|KEGG_REACTION:R07233|EC:2.1.1.187|MetaCyc:RXN-11573		molecular_function											owl:Class	
GO:0007374	biolink:NamedThing	posterior midgut invagination	Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior.	got7fsn_ti														biological_process											owl:Class	
GO:0061420	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to biotin starvation	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of biotin.	got7fsn_ti							dph	2012-01-25T09:55:39Z						biological_process											owl:Class	
GO:0002193	biolink:NamedThing	MAML1-RBP-Jkappa- ICN1 complex	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML1-CSL-Notch1 complex|MAML1-CSL-ICN1|MAML1-RBP-Jkappa-Notch1 complex						hjd	2011-08-11T04:08:18Z						cellular_component											owl:Class	
GO:1990812	biolink:NamedThing	growth cone filopodium	A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone.	got7fsn_ti							sl	2015-07-24T22:35:16Z						cellular_component											owl:Class	
GO:0102914	biolink:NamedThing	N-methyl-3-aminomethylindole N-methyltransferase activity	Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine  = H+ + gramine + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:52272|MetaCyc:RXN-8687		molecular_function											owl:Class	
GO:0043602	biolink:NamedThing	nitrate catabolic process	The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid.	got7fsn_ti	nitrate disassimilation|nitrate dissimilation													biological_process											owl:Class	
GO:0050436	biolink:NamedThing	microfibril binding	Binding to a microfibril, any small fibril occurring in biological material.	got7fsn_ti					See also the cellular component term 'microfibril ; GO:0001527'.									molecular_function											owl:Class	
GO:0033069	biolink:NamedThing	ansamycin metabolic process	The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.	got7fsn_ti	ansamycin metabolism													biological_process											owl:Class	
GO:0032257	biolink:NamedThing	maintenance of dense core granule location	Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of dense core granule localization|maintenance of dense core vesicle location													biological_process											owl:Class	
GO:0003835	biolink:NamedThing	beta-galactoside alpha-2,6-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine.	got7fsn_ti	CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase activity|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase activity|beta-galactosamide alpha-2,6-sialyltransferase activity											Reactome:R-HSA-977228|Reactome:R-HSA-977071|MetaCyc:2.4.99.1-RXN|EC:2.4.99.1|Reactome:R-HSA-975902|RHEA:11836|Reactome:R-HSA-4085033		molecular_function											owl:Class	
GO:0061182	biolink:NamedThing	negative regulation of chondrocyte development	Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.	got7fsn_ti							dph	2010-07-14T08:33:05Z						biological_process											owl:Class	
GO:0002184	biolink:NamedThing	cytoplasmic translational termination	The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.	got7fsn_ti							hjd	2011-06-09T03:17:13Z						biological_process											owl:Class	
GO:0070269	biolink:NamedThing	pyroptosis	A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.	got7fsn_ti														biological_process											owl:Class	
GO:0017084	biolink:NamedThing	delta1-pyrroline-5-carboxylate synthetase activity	Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.	got7fsn_ti	D1-pyrroline-5-carboxylate synthetase activity											Reactome:R-HSA-508040|RHEA:33207		molecular_function											owl:Class	
GO:0110105	biolink:NamedThing	mRNA cleavage and polyadenylation specificity factor complex assembly	The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex.	got7fsn_ti							kmv	2018-04-13T19:05:17Z						biological_process											owl:Class	
GO:0047730	biolink:NamedThing	carnosine synthase activity	Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine.	got7fsn_ti	L-histidine:beta-alanine ligase (AMP-forming)|carnosine-anserine synthetase activity|carnosine-homocarnosine synthetase activity|carnosine synthetase activity|homocarnosine-carnosine synthetase activity											Reactome:R-HSA-6786245|RHEA:19297|MetaCyc:CARNOSINE-SYNTHASE-RXN|EC:6.3.2.11		molecular_function											owl:Class	
GO:0000374	biolink:NamedThing	Group III intron splicing	The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.	got7fsn_ti	mRNA splicing				Note that Group III introns are known to be found in mRNA of plastids of euglenoid protists.									biological_process											owl:Class	
GO:0042359	biolink:NamedThing	vitamin D metabolic process	The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	got7fsn_ti	cholecalciferol metabolic process|ergocalciferol metabolism|calciferol metabolism|calciferol metabolic process|cholecalciferol metabolism|ergocalciferol metabolic process|vitamin D metabolism													biological_process											owl:Class	
GO:0002540	biolink:NamedThing	leukotriene production involved in inflammatory response	The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	leukotriene production involved in acute inflammatory response													biological_process											owl:Class	
GO:0018602	biolink:NamedThing	2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity	Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2.	got7fsn_ti												MetaCyc:RXN-9863|UM-BBD_reactionID:r0274|RHEA:48984		molecular_function											owl:Class	
GO:1900617	biolink:NamedThing	emericellamide A biosynthetic process	The chemical reactions and pathways resulting in the formation of emericellamide A.	got7fsn_ti	emericellamide A anabolism|emericellamide A biosynthesis|emericellamide A synthesis|emericellamide A formation						di	2012-05-15T08:00:27Z						biological_process											owl:Class	
GO:0001651	biolink:NamedThing	dense fibrillar component	A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins.	got7fsn_ti	pars fibrosa											NIF_Subcellular:sao1841764412		cellular_component											owl:Class	
GO:0043107	biolink:NamedThing	type IV pilus-dependent motility	Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.	got7fsn_ti	TFP-dependent motility|type four pilus-dependent motility|TFP-dependent movement|social gliding motility|type 4 pilus-dependent motility|twitching motility													biological_process											owl:Class	
GO:0047647	biolink:NamedThing	alkylacetylglycerophosphatase activity	Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H(2)O = 2-acetyl-1-alkyl-sn-glycerol + phosphate.	got7fsn_ti	alkylacetylglycerophosphate phosphatase activity|1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase activity|1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase activity											EC:3.1.3.59|MetaCyc:ALKYLACETYLGLYCEROPHOSPHATASE-RXN|KEGG_REACTION:R03454|RHEA:18221		molecular_function											owl:Class	
GO:0050935	biolink:NamedThing	iridophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.	got7fsn_ti	iridophore cell differentiation													biological_process											owl:Class	
GO:0030220	biolink:NamedThing	platelet formation	The process in which platelets bud from long processes extended by megakaryocytes.	got7fsn_ti	platelet extrusion													biological_process											owl:Class	
GO:0015996	biolink:NamedThing	chlorophyll catabolic process	The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products.	got7fsn_ti	chlorophyll degradation|chlorophyll breakdown|chlorophyll catabolism													biological_process											owl:Class	
GO:0061619	biolink:NamedThing	glycolytic process from mannose through fructose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.	got7fsn_ti							dph	2014-04-14T09:13:13Z						biological_process											owl:Class	
GO:0102030	biolink:NamedThing	dTDP-L-rhamnose synthetase activity	Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H+.	got7fsn_ti												MetaCyc:DTDPRHAMSYNTHMULTI-RXN		molecular_function											owl:Class	
GO:0031506	biolink:NamedThing	cell wall glycoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.	got7fsn_ti	cell wall glycoprotein anabolism|cell wall glycoprotein synthesis|cell wall glycoprotein formation|cell wall glycoprotein biosynthesis													biological_process											owl:Class	
GO:0047279	biolink:NamedThing	sn-glycerol-3-phosphate 1-galactosyltransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H(+) + UDP.	got7fsn_ti	uridine diphosphogalactose-glycerol phosphate galactosyltransferase activity|UDPgalactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity|UDPgalactose:sn-glycerol-3-phosphate alpha-D-galactosyltransferase activity|glycerol 3-phosphate 1alpha-galactosyltransferase activity|isofloridoside-phosphate synthase activity|UDP-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity|UDP-Gal:sn-glycero-3-phosphoric acid 1-alpha-galactosyl-transferase activity											MetaCyc:2.4.1.96-RXN|KEGG_REACTION:R00854|RHEA:20341|EC:2.4.1.96		molecular_function											owl:Class	
GO:0002945	biolink:NamedThing	cyclin K-CDK13 complex	A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti	CycK/Cdk13 complex						hjd	2012-12-05T16:13:28Z						cellular_component											owl:Class	
GO:0008834	biolink:NamedThing	di-trans,poly-cis-decaprenylcistransferase activity	Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate.	got7fsn_ti	undecaprenyl pyrophosphate synthase activity|undecaprenyl-diphosphate synthase activity|UPP synthetase activity|di-trans,poly-cis-undecaprenyl-diphosphate synthase activity|undecaprenyl diphosphate synthase activity|undecaprenyl pyrophosphate synthetase activity|di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity|bactoprenyl-diphosphate synthase activity|undecaprenyl diphosphate synthetase activity											MetaCyc:RXN-8999|RHEA:27551|EC:2.5.1.31		molecular_function											owl:Class	
GO:0097058	biolink:NamedThing	CRLF-CLCF1 complex	A heterodimeric protein complex that is composed of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene) and cytokine receptor-like factor 1 (product of the CRLF gene) and is secreted into the extracellular space. The CRLF-CLCF1 complex is a ligand for the ciliary neurotrophic factor (CNTF) receptor complex.	got7fsn_ti	CLF-CLC complex						pr	2011-05-26T10:37:55Z						cellular_component											owl:Class	
GO:0072673	biolink:NamedThing	lamellipodium morphogenesis	A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized.	got7fsn_ti	lamellipodium organization						mah	2011-02-21T03:11:55Z						biological_process											owl:Class	
GO:0080175	biolink:NamedThing	phragmoplast microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells.	got7fsn_ti	phragmoplast microtubule cytoskeleton organization|phragmoplast microtubule organisation						dhl	2011-04-28T03:54:11Z						biological_process											owl:Class	
GO:0050508	biolink:NamedThing	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP.	got7fsn_ti	alpha-N-acetylglucosaminyltransferase II activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity|glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase activity											MetaCyc:2.4.1.224-RXN|Reactome:R-HSA-3656254|Reactome:R-HSA-2022851|Reactome:R-HSA-3656261|Reactome:R-HSA-2022919|Reactome:R-HSA-9036283|RHEA:16213|Reactome:R-HSA-9036290|EC:2.4.1.224		molecular_function											owl:Class	
GO:0001691	biolink:NamedThing	pseudophosphatase activity	Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.	got7fsn_ti														molecular_function											owl:Class	
GO:0019212	biolink:NamedThing	phosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0060885	biolink:NamedThing	clearance of cells from fusion plate by apoptotic process	Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.	got7fsn_ti	clearance of cells from fusion plate by apoptosis						dph	2009-08-13T12:30:17Z						biological_process											owl:Class	
GO:0046505	biolink:NamedThing	sulfolipid metabolic process	The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.	got7fsn_ti	sulpholipid metabolism|sulpholipid metabolic process|sulfolipid metabolism													biological_process											owl:Class	
GO:0003150	biolink:NamedThing	muscular septum morphogenesis	The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum.	got7fsn_ti							tb	2009-09-22T07:53:28Z						biological_process											owl:Class	
GO:0070572	biolink:NamedThing	positive regulation of neuron projection regeneration	Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.	got7fsn_ti							mah	2009-04-15T01:45:27Z						biological_process											owl:Class	
GO:0010976	biolink:NamedThing	positive regulation of neuron projection development	Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	got7fsn_ti	positive regulation of neurite growth|positive regulation of neurite development|positive regulation of neurite formation|positive regulation of neurite biosynthesis						tb	2009-06-01T10:46:44Z						biological_process											owl:Class	
GO:0038008	biolink:NamedThing	TRAF-mediated signal transduction	The intracellular process in which a signal is passed on to downstream components within the cell via a tumor necrosis factor receptor-associated factor (TRAF). TRAFs are directly or indirectly recruited to the intracellular domains of cell surface receptors, and engage other signaling proteins to transfer the signal from a cell surface receptor to other intracellular signaling components.	got7fsn_ti	tumor necrosis factor receptor-associated factor signaling|tumor necrosis factor receptor-associated factor signal transduction|TRAF-mediated signalling|TRAF-mediated intracellular signaling|TRAF-mediated signaling|TRAF signaling						bf	2011-06-22T04:01:54Z						biological_process											owl:Class	
GO:0071861	biolink:NamedThing	tachykinin receptor binding	Binding to a tachykinin receptor.	got7fsn_ti							mah	2010-09-10T03:24:34Z						molecular_function											owl:Class	
GO:0036238	biolink:NamedThing	gallate dioxygenase activity	Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate.	got7fsn_ti							bf	2012-05-22T01:54:09Z				KEGG_REACTION:R09565|MetaCyc:GALLATE-DIOXYGENASE-RXN|EC:1.13.11.57|RHEA:28927		molecular_function											owl:Class	
GO:0090610	biolink:NamedThing	bundle sheath cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti							tb	2014-09-26T13:17:05Z						biological_process											owl:Class	
GO:0033718	biolink:NamedThing	pyranose dehydrogenase (acceptor) activity	Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.	got7fsn_ti	pyranose:acceptor oxidoreductase activity|quinone-dependent pyranose dehydrogenase activity|pyranose dehydrogenase activity|pyranose-quinone oxidoreductase activity|PDH											MetaCyc:RXN-7963|MetaCyc:RXN-7965|MetaCyc:RXN-7962|MetaCyc:RXN-7966|EC:1.1.99.29|MetaCyc:RXN-7961		molecular_function											owl:Class	
GO:0047615	biolink:NamedThing	actinomycin lactonase activity	Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.	got7fsn_ti	actinomycin lactonohydrolase activity											EC:3.1.1.39|MetaCyc:ACTINOMYCIN-LACTONASE-RXN		molecular_function											owl:Class	
GO:0102472	biolink:NamedThing	eriodictyol 2-hydroxylase activity	Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ <=> 2-hydroxyeriodictyol + NADP + H2O.	got7fsn_ti												RHEA:57596|MetaCyc:RXN-14077		molecular_function											owl:Class	
GO:0008855	biolink:NamedThing	exodeoxyribonuclease VII activity	Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides.	got7fsn_ti	endodeoxyribonuclease VII|E. coli exonuclease VII|exonuclease VII activity|E. coli exonuclease VII activity|Escherichia coli exonuclease VII											EC:3.1.11.6|MetaCyc:3.1.11.6-RXN		molecular_function											owl:Class	
GO:0019802	biolink:NamedThing	cyclization of glutamine involved in intein-mediated protein splicing	The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.	got7fsn_ti	cyclization of glutamine, during protein splicing				Note that this term should not be confused with 'peptidyl-pyroglutamic acid biosynthesis, using glutaminyl-peptide cyclotransferase ; GO:0017186'. See also the biological process term 'intein-mediated protein splicing ; GO:0016539'.							RESID:AA0303		biological_process											owl:Class	
GO:0016767	biolink:NamedThing	geranylgeranyl-diphosphate geranylgeranyltransferase activity	Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.	got7fsn_ti	phytoene synthetase activity|prephytoene-diphosphate synthase activity|PSase activity|geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase activity											MetaCyc:2.5.1.32-RXN|EC:2.5.1.32|RHEA:22296		molecular_function											owl:Class	
GO:0102893	biolink:NamedThing	betanidin 6-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + gomphrenin I + UDP.	got7fsn_ti												MetaCyc:RXN-8480		molecular_function											owl:Class	
GO:1990261	biolink:NamedThing	pre-mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA).	got7fsn_ti	pre-mRNA decay|unspliced RNA decay						rb	2014-01-07T23:06:44Z						biological_process											owl:Class	
GO:0071837	biolink:NamedThing	HMG box domain binding	Binding to an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin.	got7fsn_ti							mah	2010-09-10T12:05:45Z						molecular_function											owl:Class	
GO:0000294	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay	A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends.	got7fsn_ti	mRNA catabolic process, endonucleolytic|mRNA degradation, endonucleolytic cleavage-dependent decay|mRNA breakdown, endonucleolytic cleavage-dependent decay|mRNA catabolism, endonucleolytic|endonucleolytic mRNA decay|nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay													biological_process											owl:Class	
GO:0004816	biolink:NamedThing	asparagine-tRNA ligase activity	Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).	got7fsn_ti	asparaginyl transfer RNA synthetase activity|asparagyl-transfer RNA synthetase activity|asparagine translase activity|asparaginyl-tRNA synthetase activity|asparaginyl transfer ribonucleic acid synthetase activity|asparaginyl-transfer ribonucleate synthetase activity|L-asparagine:tRNAAsn ligase (AMP-forming)											Reactome:R-HSA-380227|Reactome:R-HSA-379996|KEGG_REACTION:R03648|RHEA:11180|MetaCyc:ASPARAGINE--TRNA-LIGASE-RXN|EC:6.1.1.22		molecular_function											owl:Class	
GO:0008824	biolink:NamedThing	cyanate hydratase activity	Catalysis of the reaction: cyanate + H2O = carbamate.	got7fsn_ti	cyanate lyase activity|cyanate aminohydrolase activity|carbamate hydro-lyase activity|cyanate hydrolase activity|cyanate C-N-lyase activity|cyanase activity				Note that this function was formerly EC:4.3.99.1.							EC:4.2.1.104|MetaCyc:R524-RXN|UM-BBD_reactionID:r0608|RHEA:11120		molecular_function											owl:Class	
GO:0018521	biolink:NamedThing	1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity	Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH.	got7fsn_ti	1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating)											UM-BBD_reactionID:r0224|EC:1.3.1.68|RHEA:15657|MetaCyc:1.3.1.68-RXN|KEGG_REACTION:R05314		molecular_function											owl:Class	
GO:0003304	biolink:NamedThing	myocardial epithelial involution involved in heart jogging	The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging.	got7fsn_ti							dph	2009-10-22T11:03:33Z						biological_process											owl:Class	
GO:0051971	biolink:NamedThing	positive regulation of transmission of nerve impulse	Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.	got7fsn_ti	up-regulation of transmission of nerve impulse|activation of transmission of nerve impulse|upregulation of transmission of nerve impulse|positive regulation of conduction of nerve impulse|up regulation of transmission of nerve impulse|stimulation of transmission of nerve impulse													biological_process											owl:Class	
GO:0010919	biolink:NamedThing	regulation of inositol phosphate biosynthetic process	Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	got7fsn_ti	regulation of inositol phosphate biosynthesis													biological_process											owl:Class	
GO:0071838	biolink:NamedThing	cell proliferation in bone marrow	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow.	got7fsn_ti	bone marrow cell proliferation						mah	2010-09-10T12:15:41Z						biological_process											owl:Class	
GO:0008432	biolink:NamedThing	JUN kinase binding	Binding to JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.	got7fsn_ti	JNK binding													molecular_function											owl:Class	
GO:0016443	biolink:NamedThing	bidentate ribonuclease III activity	Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.	got7fsn_ti	bidentate RNase III activity											EC:3.1.26.-		molecular_function											owl:Class	
GO:0004137	biolink:NamedThing	deoxycytidine kinase activity	Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.	got7fsn_ti	deoxycytidine kinase (phosphorylating)|arabinofuranosylcytosine kinase activity|NTP:deoxycytidine 5'-phosphotransferase activity|2'-deoxycytidine kinase activity|Ara-C kinase activity|deoxycytidine-cytidine kinase activity											EC:2.7.1.74|RHEA:20061|MetaCyc:DEOXYCYTIDINE-KINASE-RXN		molecular_function											owl:Class	
GO:0047029	biolink:NamedThing	(R)-4-hydroxyphenyllactate dehydrogenase (NADPH) activity	Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate.	got7fsn_ti	aromatic 2-oxoacid reductase activity|phenylpyruvate reductase activity|hydroxyphenylpyruvate reductase activity											https://github.com/geneontology/go-ontology/issues/21412|EC:1.1.1.110|MetaCyc:RXN-7632|RHEA:52692		molecular_function											owl:Class	
GO:0120091	biolink:NamedThing	jasmonic acid hydrolase	Catalyzes the hydroxylation of jasmonic acid to 12OH-jasmonic acid.	got7fsn_ti	2-oxoglutarate dioxygenase						krc	2017-08-18T23:25:52Z						molecular_function											owl:Class	
GO:0045298	biolink:NamedThing	tubulin complex	A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.	got7fsn_ti														cellular_component											owl:Class	
GO:0003109	biolink:NamedThing	positive regulation of the force of heart contraction by circulating norepinephrine	The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction.	got7fsn_ti	increased force of heart contraction by circulating noradrenaline|increased force of heart contraction by circulating norepinephrine													biological_process											owl:Class	
GO:0047591	biolink:NamedThing	5-hydroxypentanoate CoA-transferase activity	Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.	got7fsn_ti	5-hydroxyvalerate coenzyme A transferase activity|acetyl-CoA:5-hydroxypentanoate CoA-transferase activity|5-hydroxyvalerate CoA-transferase activity											RHEA:23496|KEGG_REACTION:R04057|MetaCyc:5-HYDROXYPENTANOATE-COA-TRANSFERASE-RXN|EC:2.8.3.14		molecular_function											owl:Class	
GO:0019671	biolink:NamedThing	glutamate catabolic process via mesaconate and citramalate	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP.	got7fsn_ti	glutamate fermentation via mesaconate and citramalate											MetaCyc:PWY-5087|MetaCyc:GLUDEG-II-PWY|MetaCyc:PWY-5088		biological_process											owl:Class	
GO:0102795	biolink:NamedThing	1-naphthaldehyde:oxygen oxidoreductase activity	Catalysis of the reaction: 1-naphthaldehyde + O2 + H2O = H+ + 1-naphthoate + hydrogen peroxide.	got7fsn_ti												MetaCyc:RXN-8090|EC:1.2.3.9		molecular_function											owl:Class	
GO:1990032	biolink:NamedThing	parallel fiber	A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium.	got7fsn_ti							pr	2013-02-07T12:58:43Z				NIF_Subcellular:nlx_330		cellular_component											owl:Class	
GO:0071195	biolink:NamedThing	Kv4.2-KChIP4 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.	got7fsn_ti							mah	2009-11-23T04:59:06Z				CORUM:3090		cellular_component											owl:Class	
GO:0018562	biolink:NamedThing	3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r0415		molecular_function											owl:Class	
GO:0106238	biolink:NamedThing	peregrinol diphosphate synthase activity	Catalysis of the reaction:peregrinol diphosphate = all-trans-geranylgeranyl diphosphate + H2O.	got7fsn_ti							hjd	2019-12-19T15:28:28Z				RHEA:54652|EC:4.2.1.174		molecular_function											owl:Class	
GO:0016156	biolink:NamedThing	fumarate reductase (NADH) activity	Catalysis of the reaction: NAD(+) + succinate = fumarate + H(+) + NADH.	got7fsn_ti	NADH-dependent fumarate reductase activity|succinate:NAD+ oxidoreductase activity|NADH-fumarate reductase activity											EC:1.3.1.6|MetaCyc:FUMARATE-REDUCTASE-NADH-RXN|KEGG_REACTION:R00402|RHEA:18281		molecular_function											owl:Class	
GO:0048212	biolink:NamedThing	Golgi vesicle uncoating	The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.	got7fsn_ti	Golgi vesicle coat depolymerization|dictyosome vesicle coat depolymerization|Golgi vesicle coat protein depolymerization|Golgi-derived vesicle uncoating													biological_process											owl:Class	
GO:0090506	biolink:NamedThing	axillary shoot meristem initiation	A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf.	got7fsn_ti	axillary bud meristem initiation						tb	2012-10-23T14:47:00Z						biological_process											owl:Class	
GO:0030860	biolink:NamedThing	regulation of polarized epithelial cell differentiation	Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0008613	biolink:NamedThing	diuretic hormone activity	The action characteristic of a diuretic hormone, a peptide hormone that, upon receptor binding, regulates water balance and fluid secretion.	got7fsn_ti														molecular_function											owl:Class	
GO:0050260	biolink:NamedThing	ribose-5-phosphate-ammonia ligase activity	Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH(4)(+) = 5-phospho-D-ribosylamine + ADP + 2 H(+) + phosphate.	got7fsn_ti	ammonia-ribose 5-phosphate aminotransferase activity|5-phosphoribosylamine synthetase activity|ribose-5-phosphate:ammonia ligase (ADP-forming)|ribose 5-phosphate aminotransferase activity											EC:6.3.4.7|MetaCyc:RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN|KEGG_REACTION:R01053|RHEA:13777		molecular_function											owl:Class	
GO:0010997	biolink:NamedThing	anaphase-promoting complex binding	Binding to an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis.	got7fsn_ti	APC binding						tb	2009-06-10T11:18:22Z						molecular_function											owl:Class	
GO:0008495	biolink:NamedThing	protoheme IX farnesyltransferase activity	Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate.	got7fsn_ti	heme A:farnesyltransferase activity|haem O synthase activity|heme O synthase activity|protohaem IX farnesyltransferase activity											MetaCyc:HEMEOSYN-RXN|Reactome:R-HSA-2995330|EC:2.5.1.141|RHEA:28070		molecular_function											owl:Class	
GO:0060279	biolink:NamedThing	positive regulation of ovulation	Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.	got7fsn_ti														biological_process											owl:Class	
GO:0060105	biolink:NamedThing	epicuticle of collagen and cuticulin-based cuticle extracellular matrix	A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans.	got7fsn_ti	epicuticle of collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0050195	biolink:NamedThing	phosphoribokinase activity	Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+).	got7fsn_ti	ATP:D-ribose-5-phosphate 1-phosphotransferase activity|phosphoribokinase (phosphorylating)											EC:2.7.1.18|KEGG_REACTION:R01050|MetaCyc:PHOSPHORIBOKINASE-RXN|RHEA:21216		molecular_function											owl:Class	
GO:0051916	biolink:NamedThing	granulocyte colony-stimulating factor binding	Binding to granulocyte colony-stimulating factor, G-CSF.	got7fsn_ti	granulocyte colony stimulating factor binding|G-CSF binding													molecular_function											owl:Class	
GO:0033949	biolink:NamedThing	fructan beta-(2,6)-fructosidase activity	Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans.	got7fsn_ti	6-FEH|beta-(2,6)-fructan exohydrolase activity|beta-(2,6)-D-fructan fructohydrolase activity											MetaCyc:3.2.1.154-RXN|EC:3.2.1.154		molecular_function											owl:Class	
GO:0017126	biolink:NamedThing	nucleologenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.	got7fsn_ti	nucleolus biogenesis|nucleolus assembly													biological_process											owl:Class	
GO:0010455	biolink:NamedThing	positive regulation of cell fate commitment	Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.	got7fsn_ti														biological_process											owl:Class	
GO:0033516	biolink:NamedThing	L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine.	got7fsn_ti	L-methionine formation from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-phospho-L-homoserine and cystathionine|methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-phospho-L-homoserine and cystathionine											MetaCyc:PWY-702		biological_process											owl:Class	
GO:0042614	biolink:NamedThing	CD70 receptor binding	Binding to a CD70, a receptor found on the surface of most activated B cells and some activated T cells.	got7fsn_ti	CD27 receptor activity|CD27L binding													molecular_function											owl:Class	
GO:0008709	biolink:NamedThing	cholate 7-alpha-dehydrogenase activity	Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH.	got7fsn_ti	7alpha-hydroxysteroid dehydrogenase activity|7-alpha-hydroxysteroid dehydrogenase activity|7alpha-HSDH|7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity|7alpha-hydroxy steroid dehydrogenase activity											RHEA:19409|EC:1.1.1.159|MetaCyc:7-ALPHA-HYDROXYSTEROID-DEH-RXN|KEGG_REACTION:R02792		molecular_function											owl:Class	
GO:0047431	biolink:NamedThing	3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity	Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 5-hydroxy-6-methylpyridine-3-carboxylate + CO(2).	got7fsn_ti	3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase (3-hydroxy-2-methylpyridine-5-carboxylate-forming)|3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase activity											KEGG_REACTION:R03461|RHEA:13669|MetaCyc:4.1.1.51-RXN|EC:4.1.1.51		molecular_function											owl:Class	
GO:0050602	biolink:NamedThing	monoprenyl isoflavone epoxidase activity	Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives.	got7fsn_ti	7-O-methylluteone,NADPH:O2 oxidoreductase activity|7-O-methylluteone:O2 oxidoreductase activity|monoprenyl isoflavone monooxygenase activity											MetaCyc:1.14.99.34-RXN|EC:1.14.99.34		molecular_function											owl:Class	
GO:0050507	biolink:NamedThing	indoxyl-UDPG glucosyltransferase activity	Catalysis of the reaction: indoxyl + UDP-D-glucose = H(+) + indican + UDP.	got7fsn_ti	UDP-glucose:indoxyl 3-O-beta-D-glucosyltransferase activity|indoxyl-UDPG-glucosyltransferase activity											EC:2.4.1.220|RHEA:12004|MetaCyc:2.4.1.220-RXN|KEGG_REACTION:R06048		molecular_function											owl:Class	
GO:1990949	biolink:NamedThing	metaphase/anaphase transition of meiosis I	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I.	got7fsn_ti	meiosis I metaphase/anaphase transition|first meiotic metaphase/anaphase transition						mah	2016-04-25T15:27:32Z						biological_process											owl:Class	
GO:0004751	biolink:NamedThing	ribose-5-phosphate isomerase activity	Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate.	got7fsn_ti	D-ribose 5-phosphate isomerase activity|phosphopentosisomerase activity|5-phosphoribose isomerase activity|ribose 5-phosphate epimerase activity|phosphopentoseisomerase activity|phosphoriboisomerase activity|ribose phosphate isomerase activity|D-ribose-5-phosphate aldose-ketose-isomerase activity|D-ribose-5-phosphate ketol-isomerase activity											EC:5.3.1.6|Reactome:R-HSA-5660013|Reactome:R-HSA-71306|KEGG_REACTION:R01056|Reactome:R-HSA-177784|RHEA:14657|Reactome:R-HSA-5660015|MetaCyc:RIB5PISOM-RXN		molecular_function											owl:Class	
GO:0010614	biolink:NamedThing	negative regulation of cardiac muscle hypertrophy	Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0008684	biolink:NamedThing	2-oxopent-4-enoate hydratase activity	Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O.	got7fsn_ti	2-keto-4-pentenoate (vinylpyruvate)hydratase activity|2-keto-4-pentenoate hydratase activity|OEH activity|4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)|4-hydroxy-2-oxopentanoate hydro-lyase activity										GO:0018821	EC:4.2.1.80|MetaCyc:2-OXOPENT-4-ENOATE-HYDRATASE-RXN|RHEA:22580|UM-BBD_enzymeID:e0078		molecular_function											owl:Class	
GO:0018832	biolink:NamedThing	halohydrin hydrogen-halide-lyase B activity	Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane.	got7fsn_ti												UM-BBD_enzymeID:e0050		molecular_function											owl:Class	
GO:1990621	biolink:NamedThing	ESCRT IV complex	An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.	got7fsn_ti	Vps4 complex|Vps4-Vta1 complex|ESCRT-IV|vacuolar protein sorting-associated complex|VPS4A/B complex|VPS4A-VPS4B|Vta1-Vps4 complex						pr	2015-01-29T10:02:30Z						cellular_component											owl:Class	
GO:0007562	biolink:NamedThing	eclosion	The emergence of an adult insect from a pupa case.	got7fsn_ti												Wikipedia:Pupa#Emergence		biological_process											owl:Class	
GO:0034383	biolink:NamedThing	low-density lipoprotein particle clearance	The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti	LDL clearance													biological_process											owl:Class	
GO:0050015	biolink:NamedThing	kievitone hydratase activity	Catalysis of the reaction: kievitone hydrate = H(2)O + H(+) + kievitone.	got7fsn_ti	kievitone-hydrate hydro-lyase (kievitone-forming)|KHase activity|kievitone-hydrate hydro-lyase activity											RHEA:23604|MetaCyc:KIEVITONE-HYDRATASE-RXN|EC:4.2.1.95|KEGG_REACTION:R03622		molecular_function											owl:Class	
GO:0102965	biolink:NamedThing	alcohol-forming fatty acyl-CoA reductase activity	Catalysis of the reaction: 2 NADPH + 2 H+ + a long-chain acyl-CoA = coenzyme A + 2 NADP + a long-chain alcohol.	got7fsn_ti												MetaCyc:RXN-9344|RHEA:52716|EC:1.2.1.84		molecular_function											owl:Class	
GO:0044570	biolink:NamedThing	starch utilization system complex	A bacterial cell envelope-associated multiprotein system, which binds and degrades starch.	got7fsn_ti	Sus complex						jl	2012-04-18T02:46:24Z						cellular_component											owl:Class	
GO:0044685	biolink:NamedThing	tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity	Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O.	got7fsn_ti							jl	2012-08-15T14:13:07Z				EC:2.1.2.-		molecular_function											owl:Class	
GO:0043885	biolink:NamedThing	carbon-monoxide dehydrogenase (ferredoxin) activity	Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin.	got7fsn_ti	carbon-monoxide,water:ferredoxin oxidoreductase activity|CO-dehydrogenase activity|CO dehydrogenase activity|carbon-monoxide dehydrogenase activity|carbon-monoxide:(acceptor) oxidoreductase activity|carbon monoxide dehydrogenase (ferredoxin) activity|CO-dehydrogenase (ferredoxin) activity|carbon monoxide dehydrogenase activity|CODH											MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN|EC:1.2.7.4		molecular_function											owl:Class	
GO:0018846	biolink:NamedThing	styrene-oxide isomerase activity	Catalysis of the reaction: styrene oxide = phenylacetaldehyde.	got7fsn_ti	styrene-oxide isomerase (epoxide-cleaving)|SOI activity|styrene oxide isomerase activity											EC:5.3.99.7|RHEA:21604|KEGG_REACTION:R02615|MetaCyc:STYRENE-OXIDE-ISOMERASE-RXN|UM-BBD_reactionID:r0034		molecular_function											owl:Class	
GO:0036340	biolink:NamedThing	chitin-based cuticle sclerotization by biomineralization	The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate.	got7fsn_ti	chitin-based cuticle hardening by biomineralisation						bf	2012-09-11T13:50:04Z						biological_process											owl:Class	
GO:0031706	biolink:NamedThing	subtype 3 bombesin receptor binding	Binding to a subtype 3 bombesin receptor.	got7fsn_ti	subtype 3 bombesin receptor ligand													molecular_function											owl:Class	
GO:0034166	biolink:NamedThing	toll-like receptor 10 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 10.	got7fsn_ti	toll-like receptor 10 signalling pathway|TLR10 signaling pathway													biological_process											owl:Class	
GO:0090140	biolink:NamedThing	regulation of mitochondrial fission	Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.	got7fsn_ti	regulation of mitochondrial division						tb	2009-12-08T02:20:48Z						biological_process											owl:Class	
GO:0140438	biolink:NamedThing	protein stearoylation	The covalent attachment of a stearoyl group to an amino acid in a protein.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18882					pg	2020-03-11T07:54:48Z						biological_process											owl:Class	
GO:0046562	biolink:NamedThing	glucose oxidase activity	Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.	got7fsn_ti	beta-D-glucose:quinone oxidoreductase activity|D-glucose oxidase activity|penatin|deoxin-1|beta-D-glucose:oxygen 1-oxidoreductase activity|D-glucose-1-oxidase activity|GOD activity|beta-D-glucose oxidase activity|beta-D-glucose:oxygen 1-oxido-reductase activity|microcid|glucose aerodehydrogenase activity|corylophyline|glucose oxyhydrase activity											RHEA:11428|MetaCyc:GLUCOSE-OXIDASE-RXN|KEGG_REACTION:R01522|EC:1.1.3.4		molecular_function											owl:Class	
GO:0044256	biolink:NamedThing	protein digestion	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0017057	biolink:NamedThing	6-phosphogluconolactonase activity	Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+).	got7fsn_ti	6-PGL|phosphogluconolactonase activity|6-phospho-D-glucono-1,5-lactone lactonohydrolase activity											Reactome:R-HSA-71296|EC:3.1.1.31|MetaCyc:6PGLUCONOLACT-RXN|KEGG_REACTION:R02035|RHEA:12556		molecular_function											owl:Class	
GO:0018802	biolink:NamedThing	2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity	Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde.	got7fsn_ti												UM-BBD_reactionID:r0370		molecular_function											owl:Class	
GO:0050188	biolink:NamedThing	phosphoenolpyruvate mutase activity	Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate.	got7fsn_ti	phosphoenolpyruvate 2,3-phosphonomutase activity|PEP phosphomutase activity|PEPPM|phosphoenolpyruvate-phosphonopyruvate phosphomutase activity|phosphoenolpyruvate phosphomutase activity|PEP mutase activity											EC:5.4.2.9|RHEA:17013|KEGG_REACTION:R00661|MetaCyc:PHOSPHOENOLPYRUVATE-MUTASE-RXN		molecular_function											owl:Class	
GO:0007161	biolink:NamedThing	calcium-independent cell-matrix adhesion	The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction.	got7fsn_ti	calcium-independent cell adhesion molecule activity													biological_process											owl:Class	
GO:1990624	biolink:NamedThing	guanyl nucleotide exchange factor inhibitor activity	Binds to and stops, prevents or reduces the activity of a guanyl nucleotide exchange factor.	got7fsn_ti							vw	2015-01-31T15:17:01Z						molecular_function											owl:Class	
GO:0060142	biolink:NamedThing	regulation of syncytium formation by plasma membrane fusion	Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0018794	biolink:NamedThing	2-hydroxyisobutyrate decarboxylase activity	Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol.	got7fsn_ti												UM-BBD_reactionID:r0617		molecular_function											owl:Class	
GO:0061602	biolink:NamedThing	molybdenum cofactor cytidylyltransferase activity	Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor.	got7fsn_ti							dph	2014-02-10T14:46:38Z				EC:2.7.7.76|RHEA:31335		molecular_function											owl:Class	
GO:0009905	biolink:NamedThing	ent-copalyl diphosphate synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate.	got7fsn_ti	diterpene cyclase activity|ent-copalyl-diphosphate lyase (decyclizing)|ent-kaurene synthetase A activity|ent-kaurene synthase A activity											RHEA:14841|KEGG_REACTION:R02068|MetaCyc:5.5.1.13-RXN|EC:5.5.1.13		molecular_function											owl:Class	
GO:0008365	biolink:NamedThing	adult chitin-based cuticle development	Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster.	got7fsn_ti	adult chitin-based cuticle anabolism|adult cuticle formation|adult chitin-based cuticle synthesis|adult cuticle biosynthetic process|adult chitin-based cuticle formation|adult chitin-based cuticle biosynthetic process|adult cuticle synthesis|adult cuticle anabolism													biological_process											owl:Class	
GO:1990712	biolink:NamedThing	HFE-transferrin receptor complex	A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription.	got7fsn_ti							pr	2015-03-26T13:03:27Z						cellular_component											owl:Class	
GO:0072541	biolink:NamedThing	peroxynitrite reductase activity	Catalysis of the reaction: 2 R-SH + ONOO- = R-SS-R + NO2- + H2O.	got7fsn_ti	peroxynitritase activity				Note that this activity is usually associated in vivo with an NADPH-dependent disulfide reductase activity, so that catalysis of the reduction of peroxynitrite to nitrite involves the possible creation of oxygen or water, using NADPH as reduction equivalent.		mah	2011-01-17T11:43:37Z						molecular_function											owl:Class	
GO:0080123	biolink:NamedThing	jasmonate-amino synthetase activity	Catalysis of the reaction: jasmonate + an amino acid = an amide-linked jasmonyl-amino acid conjugate. The substrates of this reaction include non-standard amino acids, such as ACC (1-aminocyclopropane-1-carboxylate).	got7fsn_ti	jasmonyl-amino synthetase activity|jasmonate:amino acid synthetase activity|ja-amino synthetase activity|jasmonate-amino acid synthetase activity|jasmonate-amino acid conjugate synthetase activity|jasmonate-amido synthetase activity|jasmonic acid-amino synthetase activity						dhl	2009-04-28T04:08:35Z						molecular_function											owl:Class	
GO:0002116	biolink:NamedThing	semaphorin receptor complex	A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.	got7fsn_ti	plexin-neurophilin complex													cellular_component											owl:Class	
GO:0008780	biolink:NamedThing	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity	Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine.	got7fsn_ti	UDP-N-acetylglucosamine acyltransferase activity|acyl-[acyl-carrier protein]-UDP-N-acetylglucosamine O-acyltransferase activity|(R)-3-hydroxytetradecanoyl-acyl-carrier-protein:UDP-N-acetylglucosamine 3-O-(3-hydroxytetradecanoyl)transferase activity|uridine diphosphoacetylglucosamine acyltransferase activity|acyl-acyl-carrier-protein-UDP-N-acetylglucosamine O-acyltransferase|acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase activity											MetaCyc:UDPNACETYLGLUCOSAMACYLTRANS-RXN|RHEA:13925|EC:2.3.1.129		molecular_function											owl:Class	
GO:1990165	biolink:NamedThing	single-strand break-containing DNA binding	Binding to damaged DNA containing single-strand breaks (SSBs).	got7fsn_ti	SSB-containing DNA binding|single-strand break-containing damaged DNA binding						pr	2013-08-08T11:16:04Z						molecular_function											owl:Class	
GO:0004053	biolink:NamedThing	arginase activity	Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.	got7fsn_ti	L-arginine amidinohydrolase activity|canavanase activity|arginine transamidinase activity|arginine amidinase activity|L-arginase activity											Reactome:R-HSA-70569|MetaCyc:ARGINASE-RXN|EC:3.5.3.1|RHEA:20569|Reactome:R-HSA-452036		molecular_function											owl:Class	
GO:0070533	biolink:NamedThing	BRCA1-C complex	A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.	got7fsn_ti														cellular_component											owl:Class	
GO:0090460	biolink:NamedThing	threonine homeostasis	Any process involved in the maintenance of an internal steady state of threonine within an organism or cell.	got7fsn_ti							tb	2012-09-24T14:22:02Z						biological_process											owl:Class	
GO:0004795	biolink:NamedThing	threonine synthase activity	Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate.	got7fsn_ti	O-phospho-L-homoserine phospho-lyase (adding water; L-threonine-forming)|O-phospho-L-homoserine phospho-lyase (adding water)|threonine synthetase activity											MetaCyc:THRESYN-RXN|RHEA:10840|EC:4.2.3.1		molecular_function											owl:Class	
GO:0120065	biolink:NamedThing	pyloric antrum smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach.	got7fsn_ti	antrum smooth muscle contraction						krc	2017-06-13T22:36:20Z						biological_process											owl:Class	
GO:0046658	biolink:NamedThing	anchored component of plasma membrane	The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti	anchored to plasma membrane|plasma membrane, GPI-anchored													cellular_component											owl:Class	
GO:0048881	biolink:NamedThing	mechanosensory lateral line system development	The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.	got7fsn_ti	LL system development													biological_process											owl:Class	
GO:0043802	biolink:NamedThing	hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity	Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H(2)O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H(+) + hydrogenobyrinate a,c-diamide + 2 phosphate.	got7fsn_ti	CobB|hydrogenobyrinic acid a,c diamide synthase (glutamine-hydrolysing) activity|hydrogenobyrinic-acid:L-glutamine amido-ligase (AMP-forming)											EC:6.3.5.9|KEGG_REACTION:R05224|RHEA:12544|MetaCyc:R341-RXN		molecular_function											owl:Class	
GO:0043699	biolink:NamedThing	leucosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast.	got7fsn_ti	refractosome													cellular_component											owl:Class	
GO:0050388	biolink:NamedThing	uronate dehydrogenase activity	Catalysis of the reaction: D-galacturonate + H(2)O + NAD(+) = galactarate + 2 H(+) + NADH.	got7fsn_ti	uronate: NAD-oxidoreductase activity|uronate:NAD+ 1-oxidoreductase activity|uronic acid dehydrogenase activity											KEGG_REACTION:R01981|RHEA:22404|EC:1.1.1.203|MetaCyc:URONATE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0044568	biolink:NamedThing	secondary cell wall cellulose synthase complex	A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4.	got7fsn_ti	secondary cell wall CesA complex|secondary cell-wall cellulose synthase complex|secondary cell wall CESA complex						jl	2012-04-18T12:55:04Z						cellular_component											owl:Class	
GO:0070053	biolink:NamedThing	thrombospondin receptor activity	Combining with thrombospondin and transmitting the signal to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0075514	biolink:NamedThing	endosome lysis involved in viral entry into host cell	Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm.	got7fsn_ti	viral entry into host cell via caveolae-mediated endocytosis followed by endosome lysis						jl	2011-07-27T02:56:15Z						biological_process											owl:Class	
GO:0140224	biolink:NamedThing	SLAC complex	A protein complex that regulates Arp2/3 complex-mediated actin nucleation.	got7fsn_ti							pg	2018-05-29T09:54:08Z						cellular_component											owl:Class	
GO:0034529	biolink:NamedThing	2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity	Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate.	got7fsn_ti												UM-BBD_reactionID:r0792		molecular_function											owl:Class	
GO:0060231	biolink:NamedThing	mesenchymal to epithelial transition	A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.	got7fsn_ti	mesenchymal-epithelial transition|epithelial cell differentiation from mesenchymal cell													biological_process											owl:Class	
GO:0018763	biolink:NamedThing	hydroxydechloroatrazine ethylaminohydrolase activity	Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine.	got7fsn_ti	AtzB|hydroxyatrazine ethylaminohydrolase activity|4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase activity|hydroxyatrazine hydrolase activity											RHEA:23092|UM-BBD_enzymeID:e0085|MetaCyc:R122-RXN|EC:3.5.4.43		molecular_function											owl:Class	
GO:0061347	biolink:NamedThing	planar cell polarity pathway involved in outflow tract morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.	got7fsn_ti							dph	2010-10-01T10:38:56Z						biological_process											owl:Class	
GO:0043815	biolink:NamedThing	phosphoribosylglycinamide formyltransferase 2 activity	Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate.	got7fsn_ti	5'-phosphoribosylglycinamide transformylase 2|formate-dependent GAR transformylase activity|GART 2|GAR transformylase 2											RHEA:24829|MetaCyc:GARTRANSFORMYL2-RXN		molecular_function											owl:Class	
GO:0097142	biolink:NamedThing	PUMA-BCL-2 complex	A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:43:18Z						cellular_component											owl:Class	
GO:0001958	biolink:NamedThing	endochondral ossification	Replacement ossification wherein bone tissue replaces cartilage.	got7fsn_ti												Wikipedia:Endochondral_ossification		biological_process											owl:Class	
GO:0036075	biolink:NamedThing	replacement ossification	Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation.	got7fsn_ti	indirect ossification						bf	2011-12-19T01:53:16Z						biological_process											owl:Class	
GO:0071063	biolink:NamedThing	sensory perception of wind	The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.	got7fsn_ti	perception of wind|sensory perception of air flow						mah	2009-11-04T02:40:34Z						biological_process											owl:Class	
GO:0034028	biolink:NamedThing	5-(carboxyamino)imidazole ribonucleotide synthase activity	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate.	got7fsn_ti	PurK|N5-CAIR synthetase activity|N5-carboxyaminoimidazole ribonucleotide synthetase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) activity											KEGG_REACTION:R07404|EC:6.3.4.18|RHEA:19317|MetaCyc:RXN0-742		molecular_function											owl:Class	
GO:0061419	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.	got7fsn_ti							dph	2012-01-23T01:07:43Z						biological_process											owl:Class	
GO:0018798	biolink:NamedThing	gallate decarboxylase activity	Catalysis of the reaction: gallate + H(+) = CO(2) + pyrogallol.	got7fsn_ti	gallate carboxy-lyase (pyrogallol-forming)|gallic acid decarboxylase activity|gallate carboxy-lyase activity											RHEA:12749|MetaCyc:GALLATE-DECARBOXYLASE-RXN|EC:4.1.1.59|UM-BBD_reactionID:r0005|KEGG_REACTION:R03247		molecular_function											owl:Class	
GO:0001760	biolink:NamedThing	aminocarboxymuconate-semialdehyde decarboxylase activity	Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO(2).	got7fsn_ti	2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity|2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity|alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity|picolinic acid decarboxylase activity|picolinic acid carboxylase activity|ACMSD activity|2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)|alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity											EC:4.1.1.45|MetaCyc:AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN|KEGG_REACTION:R04323|RHEA:16557		molecular_function											owl:Class	
GO:0018703	biolink:NamedThing	2,4-dichlorophenoxyacetate dehalogenase activity	Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate.	got7fsn_ti												UM-BBD_reactionID:r0280		molecular_function											owl:Class	
GO:0008488	biolink:NamedThing	gamma-glutamyl carboxylase activity	Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide.	got7fsn_ti												Reactome:R-HSA-159819|Reactome:R-HSA-159761|Reactome:R-HSA-159752|Reactome:R-HSA-163820|EC:4.1.1.90|RHEA:45140|Reactome:R-HSA-159795|Reactome:R-HSA-159803|Reactome:R-HSA-163810|Reactome:R-HSA-9673231|Reactome:R-HSA-159826|Reactome:R-HSA-6807214		molecular_function											owl:Class	
GO:0050023	biolink:NamedThing	L-fuconate dehydratase activity	Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O.	got7fsn_ti	L-fuconate hydratase activity|L-fuconate hydro-lyase (2-dehydro-3-deoxy-L-fuconate-forming)|L-fuconate hydro-lyase activity											KEGG_REACTION:R03688|EC:4.2.1.68|RHEA:22772|MetaCyc:L-FUCONATE-HYDRATASE-RXN		molecular_function											owl:Class	
GO:0036434	biolink:NamedThing	nitronate monooxygenase (FMN-linked) activity	Catalysis of the reaction: ethylnitronate + FMNH(2) + O(2) = acetaldehyde + FMN + H(2)O + H(+) + nitrite.	got7fsn_ti							bf	2013-09-16T16:20:13Z				KEGG_REACTION:R00025|RHEA:26458		molecular_function											owl:Class	
GO:0018399	biolink:NamedThing	peptidyl-phenylalanine bromination to L-4'-bromophenylalanine	The bromination of peptidyl-phenylalanine to form L-4'-bromophenylalanine.	got7fsn_ti												RESID:AA0176		biological_process											owl:Class	
GO:0036130	biolink:NamedThing	prostaglandin H2 endoperoxidase reductase activity	Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate).	got7fsn_ti	PGH2 9,11-endoperoxidase|PGH2 9-,11-endoperoxide reductase						bf	2012-03-05T09:25:03Z				KEGG_REACTION:R02264|Reactome:R-HSA-2161549|RHEA:45312		molecular_function											owl:Class	
GO:0034873	biolink:NamedThing	thioacetamide S-oxygenase activity	Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O.	got7fsn_ti												UM-BBD_reactionID:r1312		molecular_function											owl:Class	
GO:0060873	biolink:NamedThing	anterior semicircular canal development	The progession of the anterior semicircular canal from its initial formation to the mature structure.	got7fsn_ti							dph	2009-08-13T09:39:49Z						biological_process											owl:Class	
GO:0043956	biolink:NamedThing	3-hydroxypropionyl-CoA dehydratase activity	Catalysis of the reaction: 3-hydroxypropionyl-CoA = acrylyl-CoA + H2O.	got7fsn_ti	acetyl-coenzyme A synthetase|AMP-dependent synthetase and ligase|3-hydroxy propionyl-CoA dehydratase activity|enoyl-CoA hydratase/isomerase|acetyl-coenzyme A synthetase/GroES-like domain|AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase				Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.							MetaCyc:RXN-6383|RHEA:26518|EC:4.2.1.116		molecular_function											owl:Class	
GO:0071115	biolink:NamedThing	alpha5-beta1 integrin-endostatin complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.	got7fsn_ti	ITGA5-ITGB1-CAL4A3 complex						mah	2009-11-13T02:18:57Z						cellular_component											owl:Class	
GO:0047254	biolink:NamedThing	2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity	Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP.	got7fsn_ti	uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase activity|UDP-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity|UDPglucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity											MetaCyc:2.4.1.202-RXN|EC:2.4.1.202|RHEA:15541		molecular_function											owl:Class	
GO:0050549	biolink:NamedThing	cyclohexyl-isocyanide hydratase activity	Catalysis of the reaction: N-cyclohexylformamide + H(+) = cyclohexyl isocyanide + H(2)O.	got7fsn_ti	isonitrile hydratase activity|N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)|N-cyclohexylformamide hydro-lyase activity											KEGG_REACTION:R05771|UM-BBD_reactionID:r1029|MetaCyc:4.2.1.103-RXN|RHEA:18197|EC:4.2.1.103		molecular_function											owl:Class	
GO:0034688	biolink:NamedThing	integrin alphaM-beta2 complex	An integrin complex that comprises one alphaM subunit and one beta2 subunit.	got7fsn_ti	alphaM-beta2 integrin complex|Itgam-Itgb2 complex													cellular_component											owl:Class	
GO:0051802	biolink:NamedThing	regulation of cytolysis in other organism involved in symbiotic interaction	Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	regulation of cytolysis of cells in other organism involved in symbiotic interaction|regulation of cytolysis of cells in other organism during symbiotic interaction													biological_process											owl:Class	
GO:0070974	biolink:NamedThing	POU domain binding	Binding to a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.	got7fsn_ti							mah	2009-10-02T12:53:02Z						molecular_function											owl:Class	
GO:0035885	biolink:NamedThing	exochitinase activity	Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain.	got7fsn_ti							bf	2011-06-08T11:13:58Z				MetaCyc:RXN-12309|RHEA:50672		molecular_function											owl:Class	
GO:0004607	biolink:NamedThing	phosphatidylcholine-sterol O-acyltransferase activity	Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine.	got7fsn_ti	LCAT activity|phospholipid--cholesterol acyltransferase activity|lecithin:cholesterol acyltransferase activity|phosphatidylcholine:sterol O-acyltransferase activity|LCAT (lecithin-cholesterol acyltransferase)|lecithin--cholesterol acyltransferase activity											RHEA:21204|MetaCyc:2.3.1.43-RXN|Reactome:R-HSA-264695|EC:2.3.1.43		molecular_function											owl:Class	
GO:0050147	biolink:NamedThing	nucleoside ribosyltransferase activity	Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1.	got7fsn_ti	nucleoside N-ribosyltransferase activity|nucleoside:purine(pyrimidine) D-ribosyltransferase activity											MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN|EC:2.4.2.5		molecular_function											owl:Class	
GO:0062045	biolink:NamedThing	L-lysine alpha-aminotransferase	Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine.	got7fsn_ti							dph	2018-05-11T12:13:57Z						molecular_function											owl:Class	
GO:0046556	biolink:NamedThing	alpha-L-arabinofuranosidase activity	Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.	got7fsn_ti	polysaccharide alpha-L-arabinofuranosidase activity|alpha-L-arabinosidase activity|alpha-arabinosidase activity|alpha-L-arabinofuranoside arabinofuranohydrolase activity|L-arabinosidase activity|arabinosidase activity|alpha-L-arabinofuranoside hydrolase activity|alpha-arabinofuranosidase activity|alpha-L-arabinanase activity|arabinofuranosidase activity|alpha-N-arabinofuranosidase activity											EC:3.2.1.55|MetaCyc:3.2.1.55-RXN		molecular_function											owl:Class	
GO:0047592	biolink:NamedThing	5-pyridoxate dioxygenase activity	Catalysis of the reaction: 5-pyridoxate + NADPH + O(2) = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate) + NADP(+).	got7fsn_ti	5-pyridoxate oxidase activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.14.12.5.							EC:1.14.13.241|KEGG_REACTION:R04570|RHEA:11152|MetaCyc:5-PYRIDOXATE-DIOXYGENASE-RXN		molecular_function											owl:Class	
GO:0030777	biolink:NamedThing	(S)-scoulerine 9-O-methyltransferase activity	Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:(S)-scoclaurine 9-O-methyltransferase activity|S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase activity											EC:2.1.1.117|RHEA:23808|KEGG_REACTION:R03835|MetaCyc:2.1.1.117-RXN		molecular_function											owl:Class	
GO:0030848	biolink:NamedThing	threo-3-hydroxyaspartate ammonia-lyase activity	Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH(4)(+) + oxaloacetate.	got7fsn_ti	threo-3-hydroxyaspartate dehydratase activity|threo-3-hydroxy-L-aspartate ammonia-lyase activity|threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)|3-hydroxyaspartate dehydratase activity|L-threo-3-hydroxyaspartate dehydratase activity											RHEA:12424|KEGG_REACTION:R05758|MetaCyc:4.3.1.16-RXN|EC:4.3.1.16		molecular_function											owl:Class	
GO:0050102	biolink:NamedThing	cellodextrin phosphorylase activity	Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.	got7fsn_ti	1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase activity|beta-1,4-oligoglucan:orthophosphate glucosyltransferase activity											MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN|RHEA:23024|EC:2.4.1.49		molecular_function											owl:Class	
GO:0035650	biolink:NamedThing	AP-1 adaptor complex binding	Binding to an AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).	got7fsn_ti							bf	2011-01-25T10:58:52Z						molecular_function											owl:Class	
GO:0036118	biolink:NamedThing	hyaluranon cable assembly	A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.	got7fsn_ti	HA cable assembly						bf	2012-02-16T11:06:58Z						biological_process											owl:Class	
GO:0070217	biolink:NamedThing	transcription factor TFIIIB complex assembly	The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex.	got7fsn_ti	TFIIIB assembly													biological_process											owl:Class	
GO:0046066	biolink:NamedThing	dGDP metabolic process	The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).	got7fsn_ti	dGDP metabolism													biological_process											owl:Class	
GO:0060879	biolink:NamedThing	semicircular canal fusion	Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation.	got7fsn_ti							dph	2009-08-13T10:05:51Z						biological_process											owl:Class	
GO:0019325	biolink:NamedThing	anaerobic fructose catabolic process	The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.	got7fsn_ti	anaerobic fructose catabolism|anaerobic fructose degradation|anaerobic fructose breakdown											MetaCyc:ANAEROFRUCAT-PWY		biological_process											owl:Class	
GO:0019317	biolink:NamedThing	fucose catabolic process	The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose).	got7fsn_ti	fucose catabolism|fucose breakdown|fucose degradation											MetaCyc:FUCCAT-PWY		biological_process											owl:Class	
GO:0050405	biolink:NamedThing	[acetyl-CoA carboxylase] kinase activity	Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate.	got7fsn_ti	ACK2|I-peptide kinase activity|acetyl-CoA carboxylase kinase-2 activity|ACK3|STK5|acetyl-coenzyme A carboxylase kinase activity|acetyl coenzyme A carboxylase kinase (phosphorylating) activity|acetyl-CoA carboxylase kinase 2 activity|acetyl-CoA carboxylase kinase activity|acetyl-CoA carboxylase bound kinase activity|acetyl-CoA carboxylase kinase (AMP-activated) activity|acetyl-CoA carboxylase kinase (cAMP-independent) activity|AMPK|ATP:acetyl-CoA carboxylase phosphotransferase activity|acetyl-CoA carboxylase kinase-3 (AMP-activated) activity											MetaCyc:2.7.11.27-RXN|RHEA:20333|EC:2.7.11.27		molecular_function											owl:Class	
GO:0050160	biolink:NamedThing	orsellinate-depside hydrolase activity	Catalysis of the reaction: H(2)O + orsellinate depside = 2 o-orsellinate + H(+).	got7fsn_ti	lecanorate hydrolase activity											KEGG_REACTION:R00054|RHEA:19549|MetaCyc:ORSELLINATE-DEPSIDE-HYDROLASE-RXN|EC:3.1.1.40		molecular_function											owl:Class	
GO:0006398	biolink:NamedThing	mRNA 3'-end processing by stem-loop binding and cleavage	Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.	got7fsn_ti	histone mRNA 3' end processing													biological_process											owl:Class	
GO:0031722	biolink:NamedThing	hemoglobin beta binding	Binding to a hemoglobin beta chain.	got7fsn_ti														molecular_function											owl:Class	
GO:0060110	biolink:NamedThing	basal layer of collagen and cuticulin-based cuticle extracellular matrix	The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans.	got7fsn_ti	basal layer of collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0071540	biolink:NamedThing	eukaryotic translation initiation factor 3 complex, eIF3e	An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.	got7fsn_ti	eIF3e-containing eukaryotic translation initiation factor 3 complex						mah	2010-01-12T02:20:24Z						cellular_component											owl:Class	
GO:0050291	biolink:NamedThing	sphingosine N-acyltransferase activity	Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine.	got7fsn_ti	dihydroceramide synthase activity|acyl-CoA:sphingosine N-acyltransferase activity|ceramide synthetase activity|sphingosine acyltransferase activity|ceramide synthase activity											Reactome:R-HSA-428185|MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN|RHEA:23768|EC:2.3.1.24		molecular_function											owl:Class	
GO:0102189	biolink:NamedThing	4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + 2 H2O.	got7fsn_ti												MetaCyc:RXN-11957		molecular_function											owl:Class	
GO:0019803	biolink:NamedThing	peptidyl-aspartic acid carboxylation	The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid.	got7fsn_ti												RESID:AA0304		biological_process											owl:Class	
GO:0102967	biolink:NamedThing	10-hydroxygeraniol oxidoreductase activity	Catalysis of the reaction: (6E)-8-hydroxygeraniol + NADP <=> (6E)-8-hydroxygeranial + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-9367|RHEA:32607		molecular_function											owl:Class	
GO:0140627	biolink:NamedThing	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the DesCEND (destruction via C-end degron) pathway. In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.	got7fsn_ti	DesCEND	https://github.com/geneontology/go-ontology/issues/21184					pg	2021-03-24T07:30:47Z						biological_process											owl:Class	
GO:0030115	biolink:NamedThing	S-layer	A crystalline protein layer surrounding some bacteria.	got7fsn_ti												Wikipedia:S-layer		cellular_component											owl:Class	
GO:0050336	biolink:NamedThing	thioethanolamine S-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA.	got7fsn_ti	thioltransacetylase B activity|thioethanolamine acetyltransferase activity|acetyl-CoA:2-aminoethanethiol S-acetyltransferase activity|acetyl-CoA:thioethanolamine S-acetyltransferase activity											EC:2.3.1.11|RHEA:23280|MetaCyc:THIOETHANOLAMINE-S-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R03668		molecular_function											owl:Class	
GO:0071795	biolink:NamedThing	K11-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein.	got7fsn_ti							mah	2010-09-02T02:11:41Z						molecular_function											owl:Class	
GO:0047462	biolink:NamedThing	phenylalanine racemase (ATP-hydrolyzing) activity	Catalysis of the reaction: L-phenylalanine + ATP + H(2)O = D-phenylalanine + AMP + diphosphate + 2 H(+).	got7fsn_ti	phenylalanine racemase (adenosine triphosphate-hydrolysing)|phenylalanine racemase (ATP-hydrolysing)|phenylalanine racemase activity|gramicidin S synthetase I											MetaCyc:5.1.1.11-RXN|RHEA:20201|KEGG_REACTION:R00686|EC:5.1.1.11		molecular_function											owl:Class	
GO:0009899	biolink:NamedThing	ent-kaurene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate.	got7fsn_ti	ent-copalyl-diphosphate diphosphate-lyase (cyclizing)|ent-kaurene synthetase B activity|ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-kaurene-forming)|ent-kaurene synthase B activity											RHEA:22220|EC:4.2.3.19|KEGG_REACTION:R05092|MetaCyc:4.2.3.19-RXN		molecular_function											owl:Class	
GO:0016277	biolink:NamedThing	[myelin basic protein]-arginine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine.	got7fsn_ti	myelin basic protein-arginine N-methyltransferase activity|S-adenosyl-L-methionine:myelin-basic-protein-arginine omega-N-methyltransferase activity|myelin basic protein methylase activity|protein methylase I activity|myelin basic protein methylase I|S-adenosyl-L-methionine:myelin-basic-protein-arginine nomega-methyltransferase activity													molecular_function											owl:Class	
GO:0052791	biolink:NamedThing	3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity	Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain.	got7fsn_ti	2-keto-3-deoxynononic acid sialidase activity						ai	2011-10-04T04:53:49Z						molecular_function											owl:Class	
GO:0102969	biolink:NamedThing	10-oxogeraniol oxidoreductase activity	Catalysis of the reaction: (6E)-8-oxogeraniol + NADP <=> (6E)-8-oxogeranial + NADPH + H+.	got7fsn_ti												RHEA:32615|MetaCyc:RXN-9370		molecular_function											owl:Class	
GO:0033760	biolink:NamedThing	2'-deoxymugineic-acid 2'-dioxygenase activity	Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate.	got7fsn_ti	IDS3|2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) activity											KEGG_REACTION:R07185|MetaCyc:1.14.11.24-RXN|RHEA:12200|EC:1.14.11.24		molecular_function											owl:Class	
GO:0018161	biolink:NamedThing	dipyrrin biosynthetic process	The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.	got7fsn_ti	dipyrrin anabolism|dipyrromethane biosynthesis|dipyrrin biosynthesis|dipyrromethane biosynthetic process|dipyrrin synthesis|dipyrrin formation													biological_process											owl:Class	
GO:0033812	biolink:NamedThing	3-oxoadipyl-CoA thiolase activity	Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.	got7fsn_ti	succinyl-CoA:acetyl-CoA C-succinyltransferase activity											MetaCyc:RXN-3641|RHEA:19481|EC:2.3.1.174		molecular_function											owl:Class	
GO:0043781	biolink:NamedThing	cobalt-factor II C20-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III.	got7fsn_ti	cobalt-factor II C20 methyltransferase activity|cobalt-precorrin-2 C(20)-methyltransferase activity|S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase activity|CbiL											MetaCyc:RXN-8760|RHEA:17997|EC:2.1.1.151		molecular_function											owl:Class	
GO:0010383	biolink:NamedThing	cell wall polysaccharide metabolic process	The chemical reactions and pathways involving cell wall polysaccharides.	got7fsn_ti														biological_process											owl:Class	
GO:0008349	biolink:NamedThing	MAP kinase kinase kinase kinase activity	Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.	got7fsn_ti	MAP4K activity|MAPKKKK											Reactome:R-HSA-936991|Reactome:R-HSA-177692|Reactome:R-HSA-9645442		molecular_function											owl:Class	
GO:0051799	biolink:NamedThing	negative regulation of hair follicle development	Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.	got7fsn_ti	down-regulation of hair follicle development|downregulation of hair follicle development|inhibition of hair follicle development|down regulation of hair follicle development													biological_process											owl:Class	
GO:0021812	biolink:NamedThing	neuronal-glial interaction involved in cerebral cortex radial glia guided migration	The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.	got7fsn_ti	neuronal-glial interaction involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0003282	biolink:NamedThing	ventricular septum intermedium development	The progression of the ventricular septum intermedium over time, from its formation to the mature structure.	got7fsn_ti							dph	2009-10-20T10:09:53Z						biological_process											owl:Class	
GO:0047503	biolink:NamedThing	(-)-borneol dehydrogenase activity	Catalysis of the reaction: (-)-borneol + NAD(+) = (1S,4S)-camphor + H(+) + NADH.	got7fsn_ti	(-)-borneol:NAD+ oxidoreductase activity											RHEA:22128|EC:1.1.1.227|MetaCyc:--BORNEOL-DEHYDROGENASE-RXN|KEGG_REACTION:R02945		molecular_function											owl:Class	
GO:0051688	biolink:NamedThing	maintenance of plastid location	Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere.	got7fsn_ti	maintenance of plastid localization													biological_process											owl:Class	
GO:0140642	biolink:NamedThing	meiotic spindle formation (spindle phase two)	The spindle organization process in which the spindle is maintained at a constant length during meiotic metaphase.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21349					pg	2021-05-11T08:18:16Z						biological_process											owl:Class	
GO:0090306	biolink:NamedThing	meiotic spindle assembly	The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.	got7fsn_ti	spindle assembly involved in meiosis|meiotic spindle assembly	https://github.com/geneontology/go-ontology/issues/21349					tb	2010-04-09T11:21:56Z						biological_process											owl:Class	
GO:0005519	biolink:NamedThing	cytoskeletal regulatory protein binding	Binding to a protein involved in modulating the reorganization of the cytoskeleton.	got7fsn_ti														molecular_function											owl:Class	
GO:0050452	biolink:NamedThing	CoA-glutathione reductase activity	Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+.	got7fsn_ti	CoA-glutathione reductase (NADPH) activity|NADPH2:CoA-glutathione oxidoreductase activity|NADPH:CoA-glutathione oxidoreductase activity|coenzyme A glutathione disulfide reductase activity|coenzyme A disulfide-glutathione reductase activity|glutathione:NADP+ oxidoreductase (CoA-acylating)|NADPH-dependent coenzyme A-SS-glutathione reductase activity											RHEA:14617|MetaCyc:COA-GLUTATHIONE-REDUCTASE-NADPH-RXN|EC:1.8.1.10		molecular_function											owl:Class	
GO:0000448	biolink:NamedThing	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	got7fsn_ti	cleavage at C2|cleavage in ITS2 of tricistronic rRNA transcript to separate 5.8S and LSU rRNAs (SSU-rRNA, 5.8S rRNA, LSU-rRNA)										GO:0000490			biological_process											owl:Class	
GO:0140566	biolink:NamedThing	epigenetic reader	A transcription regulator that recognizes epigenetic marks such as methylated cytosines in CpG islands and modified histones, and modulates the accessibility of cis-regulatory regions to the transcription machinery.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20551					pg	2020-12-11T13:25:49Z						molecular_function											owl:Class	
GO:0018460	biolink:NamedThing	cyclohexanol dehydrogenase activity	Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+.	got7fsn_ti	cyclohexanol:NAD+ oxidoreductase activity											EC:1.1.1.245|MetaCyc:CYCLOHEXANOL-DEHYDROGENASE-RXN|RHEA:10044|UM-BBD_reactionID:r0165		molecular_function											owl:Class	
GO:0032762	biolink:NamedThing	mast cell cytokine production	Any process that contributes to cytokine production by a mast cell.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.									biological_process											owl:Class	
GO:0047268	biolink:NamedThing	galactinol-raffinose galactosyltransferase activity	Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol.	got7fsn_ti	stachyose synthetase activity|alpha-D-(1->3)-galactosyl-myo-inositol:raffinose galactosyltransferase activity											MetaCyc:2.4.1.67-RXN|EC:2.4.1.67|RHEA:20776		molecular_function											owl:Class	
GO:0035059	biolink:NamedThing	RCAF complex	A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.	got7fsn_ti	replication-coupling assembly factor complex													cellular_component											owl:Class	
GO:1900127	biolink:NamedThing	positive regulation of hyaluronan biosynthetic process	Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.	got7fsn_ti	activation of hyaluronan synthesis|up-regulation of hyaluronan biosynthesis|up-regulation of hyaluronan synthesis|upregulation of hyaluronan formation|upregulation of hyaluronan synthesis|upregulation of hyaluronan anabolism|up regulation of hyaluronan formation|activation of hyaluronan biosynthetic process|positive regulation of hyaluronan biosynthesis|up regulation of hyaluronan biosynthetic process|up regulation of hyaluronan biosynthesis|activation of hyaluronan biosynthesis|upregulation of hyaluronan biosynthetic process|up regulation of hyaluronan synthesis|upregulation of hyaluronan biosynthesis|up-regulation of hyaluronan biosynthetic process|up-regulation of hyaluronan anabolism|positive regulation of hyaluronan formation|activation of hyaluronan formation|up regulation of hyaluronan anabolism|activation of hyaluronan anabolism|positive regulation of hyaluronan anabolism|up-regulation of hyaluronan formation|positive regulation of hyaluronan synthesis						yaf	2012-02-23T01:09:33Z						biological_process											owl:Class	
GO:0071915	biolink:NamedThing	protein-lysine lysylation	The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).	got7fsn_ti	protein amino acid lysylation						mah	2010-09-24T10:01:57Z						biological_process											owl:Class	
GO:0047197	biolink:NamedThing	triglyceride-sterol O-acyltransferase activity	Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol.	got7fsn_ti	triacylglycerol:sterol acyltransferase activity|triacylglycerol:3beta-hydroxysterol O-acyltransferase activity|triacylglycerol-sterol O-acyltransferase activity											EC:2.3.1.77|RHEA:16897|MetaCyc:2.3.1.77-RXN		molecular_function											owl:Class	
GO:0033270	biolink:NamedThing	paranode region of axon	An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.	got7fsn_ti	paranode											NIF_Subcellular:sao234066064|NIF_Subcellular:sao936144858		cellular_component											owl:Class	
GO:0017005	biolink:NamedThing	3'-tyrosyl-DNA phosphodiesterase activity	Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.	got7fsn_ti					See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'.									molecular_function											owl:Class	
GO:0047316	biolink:NamedThing	glutamine-phenylpyruvate transaminase activity	Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.	got7fsn_ti	glutamine-phenylpyruvate aminotransferase activity|glutamine--phenylpyruvate aminotransferase activity|glutamine transaminase K activity|L-glutamine:phenylpyruvate aminotransferase activity											KEGG_REACTION:R01375|RHEA:17593|MetaCyc:2.6.1.64-RXN|EC:2.6.1.64		molecular_function											owl:Class	
GO:0047273	biolink:NamedThing	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide.	got7fsn_ti	UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:globotriaosylceramide beta1,3-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide beta-N-acetyl-D-galactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase activity|globoside synthetase activity|globoside synthase activity|globotriosylceramide beta-1,6-N-acetylgalactosaminyltransferase activity|beta3GalNAc-T1|UDP-N-acetyl-D-galactosamine:alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide 3III-beta-N-acetyl-D-galactosaminyltransferase activity|galactosylgalactosylglucosylceramide beta-D- activity|beta-3GalNAc-T1 activity|globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase activity										GO:0047226	MetaCyc:2.4.1.79-RXN|Reactome:R-HSA-8878914|RHEA:22252|EC:2.4.1.79		molecular_function											owl:Class	
GO:0070219	biolink:NamedThing	cellular sulfide ion homeostasis	Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell.	got7fsn_ti	cellular sulphide homeostasis|cellular sulfide homeostasis|cellular sulphide ion homeostasis													biological_process											owl:Class	
GO:0035683	biolink:NamedThing	memory T cell extravasation	The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.	got7fsn_ti	memory T-cell extravasation						bf	2011-02-23T01:10:02Z						biological_process											owl:Class	
GO:0018719	biolink:NamedThing	6-aminohexanoate transaminase activity	Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate.	got7fsn_ti												UM-BBD_reactionID:r0449|MetaCyc:R562-RXN		molecular_function											owl:Class	
GO:0047869	biolink:NamedThing	dimethylpropiothetin dethiomethylase activity	Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+).	got7fsn_ti	S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase activity|desulfhydrase activity|S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase (acrylate-forming)											EC:4.4.1.3|KEGG_REACTION:R02574|MetaCyc:DIMETHYLPROPIOTHETIN-DETHIOMETHYLASE-RXN|RHEA:19965		molecular_function											owl:Class	
GO:0071051	biolink:NamedThing	polyadenylation-dependent snoRNA 3'-end processing	Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.	got7fsn_ti	poly(A)-dependent snoRNA 3'-end processing						krc	2009-08-25T03:47:24Z						biological_process											owl:Class	
GO:0043177	biolink:NamedThing	organic acid binding	Binding to an organic acid, any acidic compound containing carbon in covalent linkage.	got7fsn_ti														molecular_function											owl:Class	
GO:0051064	biolink:NamedThing	TTP reductase activity	Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.	got7fsn_ti	TTP reduction											EC:1.17.4.-		molecular_function											owl:Class	
GO:0061360	biolink:NamedThing	optic chiasma development	The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.	got7fsn_ti	optic chiasm development						dph	2010-10-13T08:00:29Z						biological_process											owl:Class	
GO:0043431	biolink:NamedThing	2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine.	got7fsn_ti	3-demethylubiquinone-9 3-methyltransferase activity|2-octaprenyl-6-hydroxy phenol methylase activity											MetaCyc:2.1.1.64-RXN		molecular_function											owl:Class	
GO:0045785	biolink:NamedThing	positive regulation of cell adhesion	Any process that activates or increases the frequency, rate or extent of cell adhesion.	got7fsn_ti	up regulation of cell adhesion|upregulation of cell adhesion|stimulation of cell adhesion|activation of cell adhesion|up-regulation of cell adhesion													biological_process											owl:Class	
GO:0102441	biolink:NamedThing	syringetin 7-O-methyltransferase activity	Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine  <=> 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13919		molecular_function											owl:Class	
GO:0140443	biolink:NamedThing	mitochondrion-plasma membrane adaptor activity	The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.	got7fsn_ti	plasma membrane-mitochondrion adaptor activity|mitochondrion plasma membrane adaptor activity|mitochondrion plasma membrane tether activity|plasma membrane-mitochondrion tether activity	https://github.com/geneontology/go-ontology/pull/19140					pg	2020-03-24T13:11:20Z						molecular_function											owl:Class	
GO:0060240	biolink:NamedThing	negative regulation of signal transduction involved in conjugation with cellular fusion	Any process that decreases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0033816	biolink:NamedThing	diaminobutyrate acetyltransferase activity	Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+).	got7fsn_ti	DABA acetyltransferase activity|2,4-diaminobutanoate acetyltransferase activity|DAB acetyltransferase activity|acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase activity|DABAcT|acetyl-CoA:L-2,4-diaminobutanoate N4-acetyltransferase activity|L-2,4-diaminobutyrate acetyltransferase activity|diaminobutyric acid acetyltransferase activity|L-2,4-diaminobutanoate acetyltransferase activity|EctA											EC:2.3.1.178|MetaCyc:R102-RXN|KEGG_REACTION:R06978|RHEA:16901		molecular_function											owl:Class	
GO:0103025	biolink:NamedThing	alpha-amylase activity (releasing maltohexaose)	Catalysis of the reaction: n H2O + a 1,4-alpha-D-glucan = alpha-maltohexaose + a 1,4-alpha-D-glucan.	got7fsn_ti												MetaCyc:RXN0-5181|EC:3.2.1.1		molecular_function											owl:Class	
GO:0005130	biolink:NamedThing	granulocyte colony-stimulating factor receptor binding	Binding to a granulocyte colony-stimulating factor receptor.	got7fsn_ti	GC-SF receptor ligand|granulocyte colony-stimulating factor|granulocyte colony stimulating factor receptor binding|granulocyte colony-stimulating factor receptor ligand|G-CSF receptor ligand													molecular_function											owl:Class	
GO:0052609	biolink:NamedThing	4-ketotorulene 3-hydroxylase activity	Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O.	got7fsn_ti	carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity											MetaCyc:RXN-8218		molecular_function											owl:Class	
GO:0072576	biolink:NamedThing	liver morphogenesis	The process in which the anatomical structures of the liver are generated and organized.	got7fsn_ti							mah	2011-02-02T03:41:30Z						biological_process											owl:Class	
GO:0070084	biolink:NamedThing	protein initiator methionine removal	The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein.	got7fsn_ti	removal of initiator methionine from protein													biological_process											owl:Class	
GO:0097206	biolink:NamedThing	nephrocyte filtration	The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm.	got7fsn_ti							pr	2012-01-03T03:13:31Z						biological_process											owl:Class	
GO:0047191	biolink:NamedThing	1-alkylglycerophosphocholine O-acyltransferase activity	Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA.	got7fsn_ti	acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase activity											EC:2.3.1.63|MetaCyc:2.3.1.63-RXN|RHEA:23992		molecular_function											owl:Class	
GO:0008336	biolink:NamedThing	gamma-butyrobetaine dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate.	got7fsn_ti	g-butyrobetaine dioxygenase activity|gamma-BBH activity|gamma-butyrobetaine,2-oxoglutarate dioxygenase activity|gamma-butyrobetaine hydroxylase activity|4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|alpha-butyrobetaine hydroxylase activity|butyrobetaine hydroxylase activity											KEGG_REACTION:R02397|EC:1.14.11.1|Reactome:R-HSA-71261|MetaCyc:1.14.11.1-RXN|RHEA:24028		molecular_function											owl:Class	
GO:0102506	biolink:NamedThing	cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose = cyanin betaine + ferulate + H+.	got7fsn_ti												EC:2.4.1.299|MetaCyc:RXN-14432		molecular_function											owl:Class	
GO:0034665	biolink:NamedThing	integrin alpha1-beta1 complex	An integrin complex that comprises one alpha1 subunit and one beta1 subunit.	got7fsn_ti	ITGA1-ITGB1 complex|VLA-1 complex|alpha1-beta1 integrin complex													cellular_component											owl:Class	
GO:0050512	biolink:NamedThing	lactosylceramide 4-alpha-galactosyltransferase activity	Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP.	got7fsn_ti	Gal-beta-(1,4)-Glc-beta-1-Cer alpha-(1,4)-galactosyltransferase activity|histo-blood group Pk UDP-galactose|histo-blood group P(k) UDP-galactose activity|Gal-beta-1,4-Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity|UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase activity|lactosylceramide 4-a-galactosyltransferase activity|globotriaosylceramide/CD77 synthase activity											RHEA:11924|MetaCyc:2.4.1.228-RXN|EC:2.4.1.228		molecular_function											owl:Class	
GO:0018219	biolink:NamedThing	peptidyl-cysteine S-acetylation	The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine.	got7fsn_ti												RESID:AA0056		biological_process											owl:Class	
GO:0034917	biolink:NamedThing	2-methylhex-2-enoyl-CoA hydratase activity	Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0929		molecular_function											owl:Class	
GO:0033919	biolink:NamedThing	glucan 1,3-alpha-glucosidase activity	Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans.	got7fsn_ti	glucosidase II activity|exo-1,3-alpha-glucanase activity|1,3-alpha-D-glucan 3-glucohydrolase activity											EC:3.2.1.84|Reactome:R-HSA-9683663|MetaCyc:3.2.1.84-RXN|Reactome:R-HSA-532667|Reactome:R-HSA-9694364|Reactome:R-HSA-548890		molecular_function											owl:Class	
GO:0120147	biolink:NamedThing	Formylglycine-generating oxidase activity	Catalysis of the reaction: A [sulfatase]-L-cysteine + O(2) + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H(2)O.	got7fsn_ti							krc	2018-04-06T15:38:52Z				EC:1.8.3.7|RHEA:51152|MetaCyc:RXN-16226		molecular_function											owl:Class	
GO:0048159	biolink:NamedThing	primary oocyte stage	The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells.	got7fsn_ti	mammalian oogenesis stage 2													biological_process											owl:Class	
GO:0046509	biolink:NamedThing	1,2-diacylglycerol 3-beta-galactosyltransferase activity	Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP.	got7fsn_ti	1beta-MGDG|UDP-galactose:diacylglycerol galactosyltransferase activity|UDP-galactose-diacylglyceride galactosyltransferase activity|1-beta-MGDG activity|UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase activity|uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase activity|UDP galactose-1,2-diacylglycerol galactosyltransferase activity|UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase activity|monogalactosyldiacylglycerol synthase activity|MGDG synthase activity											KEGG_REACTION:R02691|RHEA:14945|MetaCyc:2.4.1.46-RXN|EC:2.4.1.46		molecular_function											owl:Class	
GO:0008031	biolink:NamedThing	eclosion hormone activity	The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis.	got7fsn_ti														molecular_function											owl:Class	
GO:0047493	biolink:NamedThing	ceramide cholinephosphotransferase activity	Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin.	got7fsn_ti	CDP-choline:N-acylsphingosine cholinephosphotransferase activity|phosphorylcholine-ceramide transferase activity											EC:2.7.8.3|KEGG_REACTION:R01891|MetaCyc:CERAMIDE-CHOLINEPHOSPHOTRANSFERASE-RXN|RHEA:16273		molecular_function											owl:Class	
GO:0008775	biolink:NamedThing	acetate CoA-transferase activity	Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.	got7fsn_ti	acetate coenzyme A-transferase activity|butyryl CoA:acetate CoA transferase activity|acyl-CoA:acetate CoA-transferase activity|acetyl-CoA:acetoacetate CoA transferase activity|succinyl-CoA:acetate CoA transferase activity|butyryl coenzyme A transferase activity											EC:2.8.3.8|UM-BBD_enzymeID:e0012|Reactome:R-HSA-2066788|RHEA:13381|MetaCyc:ACECOATRANS-RXN		molecular_function											owl:Class	
GO:0090436	biolink:NamedThing	leaf pavement cell development	The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate.	got7fsn_ti							tb	2012-07-31T16:08:53Z						biological_process											owl:Class	
GO:0061831	biolink:NamedThing	apical ectoplasmic specialization	Testis-specific junction between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.	got7fsn_ti	apical ES													cellular_component											owl:Class	
GO:0103104	biolink:NamedThing	6-methylthiohexyldesulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 6-methylthiohexyldesulfoglucosinolate + 3'-phosphonato-5'-adenylyl sulfate <=> adenosine 3',5'-bismonophosphate + H+ + 6-methylthiohexylglucosinolate.	got7fsn_ti												MetaCyc:RXNQT-4331		molecular_function											owl:Class	
GO:0036027	biolink:NamedThing	protein C inhibitor-PLAU complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator.	got7fsn_ti	serpin A5-PLAU complex|plasma serine protease inhibitor-PLAU complex|protein C inhibitor-urokinase-type plasminogen activator complex|protein C inhibitor-uPA complex|PCI-PLAU complex|protein C inhibitor-U-plasminogen activator complex|SERPINA5-PLAU complex						bf	2011-10-19T01:37:03Z						cellular_component											owl:Class	
GO:0071205	biolink:NamedThing	protein localization to juxtaparanode region of axon	Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon.	got7fsn_ti	protein localisation to juxtaparanode region of axon						mah	2009-11-25T01:13:55Z						biological_process											owl:Class	
GO:0097088	biolink:NamedThing	interleukin-17F production	The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-17F production						pr	2011-06-23T11:32:59Z						biological_process											owl:Class	
GO:0072300	biolink:NamedThing	positive regulation of metanephric glomerulus development	Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.	got7fsn_ti							mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:0004382	biolink:NamedThing	guanosine-diphosphatase activity	Catalysis of the reaction: GDP + H2O = GMP + phosphate.	got7fsn_ti	GDP phosphohydrolase activity|guanosine diphosphatase activity|guanosine 5'-diphosphatase activity|GDPase activity											MetaCyc:GUANOSINE-DIPHOSPHATASE-RXN|RHEA:22156|EC:3.6.1.42		molecular_function											owl:Class	
GO:0097262	biolink:NamedThing	eoxin D4 synthase activity	Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid.	got7fsn_ti							pr	2012-03-08T03:01:00Z				Reactome:R-HSA-2161945		molecular_function											owl:Class	
GO:0047521	biolink:NamedThing	3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH.	got7fsn_ti	12-beta-hydroxysteroid dehydrogenase activity|12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity|12beta-hydroxysteroid dehydrogenase activity											MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN|EC:1.1.1.238|KEGG_REACTION:R03495|RHEA:21424		molecular_function											owl:Class	
GO:0004788	biolink:NamedThing	thiamine diphosphokinase activity	Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.	got7fsn_ti	thiaminokinase activity|ATP:thiamin pyrophosphotransferase activity|thiamin:ATP pyrophosphotransferase activity|thiamine pyrophosphokinase activity|thiamin pyrophosphotransferase activity|TPTase activity|ATP:thiamine diphosphotransferase activity|thiamin diphosphokinase activity|thiamin pyrophosphokinase activity											RHEA:11576|Reactome:R-HSA-196761|EC:2.7.6.2|MetaCyc:THIAMIN-PYROPHOSPHOKINASE-RXN		molecular_function											owl:Class	
GO:0034185	biolink:NamedThing	apolipoprotein binding	Binding to an apolipoprotein, the protein component of a lipoprotein complex.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:39015	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005947	biolink:NamedThing	mitochondrial alpha-ketoglutarate dehydrogenase complex	Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.	got7fsn_ti	2-oxoglutarate dehydrogenase complex													cellular_component											owl:Class	
GO:1902892	biolink:NamedThing	positive regulation of root hair elongation	Any process that activates or increases the frequency, rate or extent of root hair elongation.	got7fsn_ti	up regulation of root hair elongation|activation of root hair elongation|upregulation of root hair elongation|up-regulation of root hair elongation						als	2014-04-07T13:46:53Z						biological_process											owl:Class	
GO:1905079	biolink:NamedThing	regulation of cerebellar neuron development	Any process that modulates the frequency, rate or extent of cerebellar neuron development.	got7fsn_ti							hjd	2016-03-24T19:45:17Z						biological_process											owl:Class	
NCBITaxon:147537	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905789	biolink:NamedThing	positive regulation of detection of mechanical stimulus involved in sensory perception of touch	Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.	got7fsn_ti	up regulation of sensory transduction of mechanical stimulus during perception of touch|upregulation of detection of mechanical stimulus involved in sensory perception of touch|up regulation of perception of touch, sensory transduction of mechanical stimulus|up regulation of sensory detection of mechanical stimulus during perception of touch|activation of perception of touch, detection of mechanical stimulus|up-regulation of tactition, sensory detection of mechanical stimulus|up regulation of tactition, sensory detection of mechanical stimulus|upregulation of perception of touch, sensory detection of mechanical stimulus|up-regulation of sensory detection of mechanical stimulus during perception of touch|up-regulation of detection of mechanical stimulus involved in sensory perception of touch|positive regulation of sensory transduction of mechanical stimulus during perception of touch|up regulation of detection of mechanical stimulus involved in sensory perception of touch|up regulation of perception of touch, detection of mechanical stimulus|positive regulation of tactition, sensory detection of mechanical stimulus|upregulation of perception of touch, sensory transduction of mechanical stimulus|up-regulation of perception of touch, detection of mechanical stimulus|activation of detection of mechanical stimulus involved in sensory perception of touch|up-regulation of perception of touch, sensory detection of mechanical stimulus|up regulation of perception of touch, sensory detection of mechanical stimulus|up-regulation of perception of touch, sensory transduction of mechanical stimulus|positive regulation of perception of touch, sensory detection of mechanical stimulus|upregulation of tactition, sensory detection of mechanical stimulus|upregulation of perception of touch, detection of mechanical stimulus|activation of perception of touch, sensory transduction of mechanical stimulus|positive regulation of perception of touch, detection of mechanical stimulus|upregulation of sensory transduction of mechanical stimulus during perception of touch|activation of sensory detection of mechanical stimulus during perception of touch|up-regulation of sensory transduction of mechanical stimulus during perception of touch|upregulation of sensory detection of mechanical stimulus during perception of touch|positive regulation of sensory detection of mechanical stimulus during perception of touch|activation of perception of touch, sensory detection of mechanical stimulus|activation of tactition, sensory detection of mechanical stimulus|positive regulation of perception of touch, sensory transduction of mechanical stimulus|activation of sensory transduction of mechanical stimulus during perception of touch						hbye	2017-01-09T15:11:23Z						biological_process											owl:Class	
GO:0038165	biolink:NamedThing	oncostatin-M-mediated signaling pathway	A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.	got7fsn_ti	oncostatin-M signaling pathway|OSM signaling pathway						bf	2012-05-14T02:54:30Z						biological_process											owl:Class	
GO:1990235	biolink:NamedThing	diamine N-acetyltransferase complex	A protein complex which is capable of diamine N-acetyltransferase activity.	got7fsn_ti	SAT complex|spermidine acetyltransferase complex|SAT tetramer						bhm	2013-11-13T16:29:45Z						cellular_component											owl:Class	
GO:0044222	biolink:NamedThing	anammoxosome	An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism.	got7fsn_ti							jl	2009-11-12T04:03:24Z						cellular_component											owl:Class	
GO:0002900	biolink:NamedThing	positive regulation of central B cell deletion	Any process that activates or increases the frequency, rate, or extent of central B cell deletion.	got7fsn_ti	up-regulation of central B cell deletion|stimulation of central B cell deletion|activation of central B cell deletion|up regulation of central B cell deletion|upregulation of central B cell deletion													biological_process											owl:Class	
GO:0031357	biolink:NamedThing	integral component of chloroplast inner membrane	The component of the chloroplast inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to chloroplast inner membrane													cellular_component											owl:Class	
GO:0015244	biolink:NamedThing	fluconazole transmembrane transporter activity	Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.	got7fsn_ti	fluconazole transporter activity													molecular_function											owl:Class	
GO:0015903	biolink:NamedThing	fluconazole transport	The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.	got7fsn_ti														biological_process											owl:Class	
GO:0120019	biolink:NamedThing	phosphatidylcholine transfer activity	Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	phosphatidylcholine carrier activity|intermembrane phosphatidylcholine transfer activity	https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-17T04:22:47Z						molecular_function											owl:Class	
GO:0031210	biolink:NamedThing	phosphatidylcholine binding	Binding to a phosphatidylcholine, a glycophospholipid in which a phosphatidyl group is esterified to the hydroxyl group of choline.	got7fsn_ti														molecular_function											owl:Class	
GO:0106098	biolink:NamedThing	NAGS/NAGK complex	A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate.	got7fsn_ti							hjd	2018-02-15T00:22:31Z						cellular_component											owl:Class	
GO:0140445	biolink:NamedThing	chromosome, telomeric repeat region	A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA and seal the telomeric loop.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19086					pg	2020-03-27T13:29:16Z						cellular_component											owl:Class	
GO:0051893	biolink:NamedThing	regulation of focal adhesion assembly	Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.	got7fsn_ti	regulation of adhesion plaque assembly													biological_process											owl:Class	
GO:0120014	biolink:NamedThing	phospholipid transfer activity	Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	phospholipid carrier activity|intermembrane phospholipid transfer activity	https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-17T03:34:17Z						molecular_function											owl:Class	
GO:2000103	biolink:NamedThing	positive regulation of mammary stem cell proliferation	Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation.	got7fsn_ti							dph	2010-09-14T06:10:36Z						biological_process											owl:Class	
GO:0015123	biolink:NamedThing	acetate transmembrane transporter activity	Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0062073	biolink:NamedThing	histone mRNA stem-loop binding complex	A protein-containing complex composed of a stem-loop binding protein (in most species SLBP) and its interacting partner (SLIP1 or MIF4GD in most species) that binds to the histone mRNA (hmRNA) 3-prime-stem-loop structure. Facilitates hmRNA translation initiation and may also be involved in its processing and nuclear export.	got7fsn_ti	SLBP-MIF4GD complex|SLBP-SLIP1 complex						dph	2018-09-10T13:46:56Z						cellular_component											owl:Class	
GO:1901239	biolink:NamedThing	malonate(1-) transmembrane transporter activity	Enables the transfer of malonate(1-) from one side of a membrane to the other.	got7fsn_ti	malonic acid uptake transmembrane transporter activity						al	2012-08-07T15:09:02Z			GO:1901549	RHEA:33115		molecular_function											owl:Class	
GO:1901553	biolink:NamedThing	malonic acid transmembrane transport	The directed movement of malonic acid across a membrane.	got7fsn_ti	malonic acid membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		pr	2012-10-30T15:23:54Z						biological_process											owl:Class	
GO:0038021	biolink:NamedThing	leptin receptor activity	Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti							bf	2011-06-27T01:36:45Z						molecular_function											owl:Class	
GO:0000425	biolink:NamedThing	pexophagy	The selective autophagy process in which a peroxisome is degraded by macroautophagy.	got7fsn_ti	macropexophagy													biological_process											owl:Class	
GO:0015827	biolink:NamedThing	tryptophan transport	The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-tryptophan transport													biological_process											owl:Class	
GO:0060297	biolink:NamedThing	regulation of sarcomere organization	Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	got7fsn_ti	regulation of sarcomere organisation													biological_process											owl:Class	
GO:0043942	biolink:NamedThing	negative regulation of sexual sporulation resulting in formation of a cellular spore	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0014018	biolink:NamedThing	neuroblast fate specification	The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0097052	biolink:NamedThing	L-kynurenine metabolic process	The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).	got7fsn_ti	L-kynurenine metabolism						pr	2011-05-24T03:28:44Z						biological_process											owl:Class	
GO:0032117	biolink:NamedThing	horsetail-astral microtubule array	An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement.	got7fsn_ti	HAA													cellular_component											owl:Class	
GO:0010610	biolink:NamedThing	regulation of mRNA stability involved in response to stress	Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.	got7fsn_ti														biological_process											owl:Class	
GO:0120281	biolink:NamedThing	autolysosome membrane	A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20239					krc	2020-11-17T02:46:19Z						cellular_component											owl:Class	
GO:0060669	biolink:NamedThing	embryonic placenta morphogenesis	The process in which the embryonic placenta is generated and organized.	got7fsn_ti							dph	2009-06-02T09:33:37Z						biological_process											owl:Class	
GO:0034507	biolink:NamedThing	chromosome, centromeric outer repeat region	The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it.	got7fsn_ti	chromosome, centric outer repeat region													cellular_component											owl:Class	
GO:1903381	biolink:NamedThing	regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.	got7fsn_ti	regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|regulation of endoplasmic reticulum stress-induced neuron apoptosis|regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of ER stress-induced neuron apoptosis						bf	2014-08-27T08:45:29Z						biological_process											owl:Class	
GO:0120110	biolink:NamedThing	interphase mitotic telomere clustering	The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope.	got7fsn_ti	mitotic telomere clustering during interphase				It is likely that both intra chromosome telomere clustering and inter-chromosome occur because a single focus is sometimes observed, although this has yet to be proven.		krc	2017-11-01T18:09:08Z						biological_process											owl:Class	
GO:0055021	biolink:NamedThing	regulation of cardiac muscle tissue growth	Any process that modulates the frequency, rate or extent of cardiac muscle growth.	got7fsn_ti														biological_process											owl:Class	
GO:0061932	biolink:NamedThing	negative regulation of erythrocyte enucleation	Any process that decreases the frequency, rate or extent of erythrocyte enucleation.	got7fsn_ti							dph	2017-09-05T13:00:15Z						biological_process											owl:Class	
GO:0061178	biolink:NamedThing	regulation of insulin secretion involved in cellular response to glucose stimulus	Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.	got7fsn_ti	regulation of insulin secretion in response to glucose						dph	2010-07-13T09:38:42Z						biological_process											owl:Class	
GO:0071402	biolink:NamedThing	cellular response to lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.	got7fsn_ti							mah	2009-12-14T02:48:51Z						biological_process											owl:Class	
GO:0008645	biolink:NamedThing	hexose transmembrane transport	The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule.	got7fsn_ti	low-affinity hexose transport|hexose transport|hexose membrane transport|high-affinity hexose transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T10:27:23Z			GO:0035428|GO:0008647|GO:0008646			biological_process											owl:Class	
GO:0150200	biolink:NamedThing	regulation of transport across blood-brain barrier	Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier.	got7fsn_ti							bc	2020-03-26T19:22:26Z						biological_process											owl:Class	
GO:1900137	biolink:NamedThing	negative regulation of chemokine activity	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity.	got7fsn_ti	down-regulation of chemokine activity|inhibition of chemokine activity|downregulation of chemokine activity|down regulation of chemokine activity						bf	2012-02-28T01:36:33Z						biological_process											owl:Class	
GO:0045700	biolink:NamedThing	regulation of spermatid nuclear differentiation	Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1905881	biolink:NamedThing	positive regulation of oogenesis	Any process that activates or increases the frequency, rate or extent of oogenesis.	got7fsn_ti	up regulation of ovum development|positive regulation of ovum development|up-regulation of oogenesis|upregulation of ovum development|up-regulation of ovum development|activation of ovum development|activation of oogenesis|upregulation of oogenesis|up regulation of oogenesis						hbye	2017-01-31T09:31:23Z						biological_process											owl:Class	
GO:1903425	biolink:NamedThing	fluoride transmembrane transporter activity	Enables the transfer of fluoride from one side of a membrane to the other.	got7fsn_ti							mcc	2014-09-09T21:27:55Z						molecular_function											owl:Class	
GO:1903424	biolink:NamedThing	fluoride transmembrane transport	The process in which fluoride is transported across a membrane.	got7fsn_ti	transmembrane fluoride transport|fluoride membrane transport						mcc	2014-09-09T21:21:01Z						biological_process											owl:Class	
GO:0033157	biolink:NamedThing	regulation of intracellular protein transport	Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.	got7fsn_ti														biological_process											owl:Class	
GO:0045167	biolink:NamedThing	asymmetric protein localization involved in cell fate determination	Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.	got7fsn_ti	asymmetric protein localization involved in cell fate commitment|asymmetric protein localization resulting in cell fate commitment|cell fate commitment, asymmetric protein localization|asymmetric protein localisation involved in cell fate determination													biological_process											owl:Class	
GO:1904158	biolink:NamedThing	axonemal central apparatus assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus.	got7fsn_ti	axonemal central apparatus formation						krc	2015-04-16T18:46:11Z						biological_process											owl:Class	
GO:0016318	biolink:NamedThing	ommatidial rotation	The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.	got7fsn_ti														biological_process											owl:Class	
GO:0035452	biolink:NamedThing	extrinsic component of plastid membrane	The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	peripheral to plastid membrane|extrinsic to plastid membrane						bf	2010-04-16T10:19:33Z						cellular_component											owl:Class	
GO:1905410	biolink:NamedThing	regulation of mitotic cohesin unloading	Any process that modulates the frequency, rate or extent of mitotic cohesin unloading.	got7fsn_ti							vw	2016-08-25T15:45:22Z						biological_process											owl:Class	
GO:0071657	biolink:NamedThing	positive regulation of granulocyte colony-stimulating factor production	Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.	got7fsn_ti	positive regulation of lenograstim production|positive regulation of colony stimulating factor 3 (granulocyte) production|positive regulation of CSF3 production|positive regulation of G-CSF production|positive regulation of pluripoietin production|positive regulation of granulocyte colony stimulating factor production|positive regulation of filgrastim production						mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:1904838	biolink:NamedThing	regulation of male germ-line stem cell asymmetric division	Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division.	got7fsn_ti	regulation of male germ-line stem cell renewal						sl	2015-12-05T00:28:31Z						biological_process											owl:Class	
GO:0003098	biolink:NamedThing	tubuloglomerular feedback	The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus.	got7fsn_ti												Wikipedia:Tubuloglomerular_feedback		biological_process											owl:Class	
GO:0002788	biolink:NamedThing	regulation of antifungal peptide production	Any process that modulates the frequency, rate, or extent of antifungal peptide production.	got7fsn_ti														biological_process											owl:Class	
GO:0120016	biolink:NamedThing	sphingolipid transfer activity	Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	sphingolipid carrier activity|intermembrane sphingolipid transfer activity	https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-17T03:52:30Z						molecular_function											owl:Class	
GO:0046625	biolink:NamedThing	sphingolipid binding	Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	got7fsn_ti														molecular_function											owl:Class	
GO:0140241	biolink:NamedThing	translation at synapse	Translation that occurs at the synapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/210			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:23:12Z						biological_process											owl:Class	
GO:1901191	biolink:NamedThing	negative regulation of formation of translation initiation ternary complex	Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.	got7fsn_ti	down-regulation of formation of translation initiation ternary complex|inhibition of translation initiation ternary complex assembly|inhibition of formation of translation initiation ternary complex|downregulation of formation of translation initiation ternary complex|downregulation of translation initiation ternary complex assembly|down-regulation of translation initiation ternary complex assembly|down regulation of formation of translation initiation ternary complex|down regulation of translation initiation ternary complex assembly|negative regulation of translation initiation ternary complex assembly						ss	2012-07-25T02:27:21Z						biological_process											owl:Class	
GO:0071383	biolink:NamedThing	cellular response to steroid hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.	got7fsn_ti							mah	2009-12-11T03:49:02Z						biological_process											owl:Class	
GO:2000432	biolink:NamedThing	negative regulation of cytokinesis, actomyosin contractile ring assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.	got7fsn_ti	negative regulation of contractile ring assembly						vw	2011-03-03T12:18:16Z						biological_process											owl:Class	
GO:1900242	biolink:NamedThing	regulation of synaptic vesicle endocytosis	Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis.	got7fsn_ti	regulation of synaptic vesicle retrieval						rl	2012-03-28T01:40:26Z						biological_process											owl:Class	
GO:1902736	biolink:NamedThing	positive regulation of receptor-mediated virion attachment to host cell	Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell.	got7fsn_ti	up-regulation of virion attachment, binding of host cell surface receptor|activation of receptor-mediated virion attachment to host cell|upregulation of receptor-mediated virion attachment to host cell|positive regulation of virion attachment, binding of host cell surface receptor|up regulation of receptor-mediated virion attachment to host cell|up regulation of virion attachment, binding of host cell surface receptor|up-regulation of receptor-mediated virion attachment to host cell|activation of virion attachment, binding of host cell surface receptor|upregulation of virion attachment, binding of host cell surface receptor						als	2014-02-25T12:26:16Z						biological_process											owl:Class	
GO:0017109	biolink:NamedThing	glutamate-cysteine ligase complex	An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine.	got7fsn_ti	gamma-glutamylcysteine synthetase complex													cellular_component											owl:Class	
CHEBI:350546	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097104	biolink:NamedThing	postsynaptic membrane assembly	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).	got7fsn_ti	post-synaptic membrane assembly						pr	2011-07-27T01:26:49Z						biological_process											owl:Class	
GO:0061889	biolink:NamedThing	negative regulation of astrocyte activation	Any process that decreases the frequency, rate or extent of astrocyte activation.	got7fsn_ti							dph	2017-06-01T22:29:43Z						biological_process											owl:Class	
GO:0000229	biolink:NamedThing	cytoplasmic chromosome	A chromosome found in the cytoplasm.	got7fsn_ti	cytoplasmic interphase chromosome													cellular_component											owl:Class	
GO:1903437	biolink:NamedThing	negative regulation of mitotic cytokinetic process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process.	got7fsn_ti	inhibition of mitotic cytokinetic process|down-regulation of mitotic cytokinetic process|down regulation of mitotic cytokinetic process|downregulation of mitotic cytokinetic process						tb	2014-09-15T23:11:47Z						biological_process											owl:Class	
GO:0102025	biolink:NamedThing	ABC-type thiosulfate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).	got7fsn_ti	thiosulfate transmembrane-transporting ATPase activity|thiosulphate ABC transporter activity|ATPase-coupled thiosulfate transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/14642									GO:0032146	RHEA:29871|MetaCyc:ABC-7-RXN|EC:7.3.2.3		molecular_function											owl:Class	
GO:0015709	biolink:NamedThing	thiosulfate transport	The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	thiosulphate transport													biological_process											owl:Class	
GO:0062248	biolink:NamedThing	cleistothecium formation	The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	got7fsn_ti							dph	2020-05-08T16:14:06Z						biological_process											owl:Class	
GO:1904875	biolink:NamedThing	regulation of DNA ligase activity	Any process that modulates the frequency, rate or extent of DNA ligase activity.	got7fsn_ti							rl	2015-12-18T18:35:30Z						biological_process											owl:Class	
GO:0015416	biolink:NamedThing	ABC-type phosphonate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).	got7fsn_ti	phosphonate ABC transporter|ATPase-coupled alkylphosphonate transmembrane transporter activity|alkylphosphonate transmembrane-transporting ATPase activity|alkylphosphonate ABC transporter activity|organic phosphonate transmembrane-transporting ATPase activity|ATP phosphohydrolase (phosphonate-transporting)|phosphonate-transporting ATPase activity|ATPase-coupled organic phosphonate transmembrane transporter activity|organic phosphonate transmembrane transporter activity|alkylphosphonate transmembrane transporter activity|phosphonate transporting ATPase activity										GO:0102017|GO:0042917|GO:0015604	RHEA:18065|MetaCyc:3.6.3.28-RXN|EC:7.3.2.2|MetaCyc:ABC-23-RXN		molecular_function											owl:Class	
GO:0015716	biolink:NamedThing	organic phosphonate transport	The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).	got7fsn_ti	alkylphosphonate transport	https://github.com/geneontology/go-ontology/issues/17164									GO:0042916			biological_process											owl:Class	
GO:1904876	biolink:NamedThing	negative regulation of DNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.	got7fsn_ti	downregulation of DNA ligase activity|inhibition of DNA ligase activity|down regulation of DNA ligase activity|down-regulation of DNA ligase activity						rl	2015-12-18T18:35:37Z						biological_process											owl:Class	
GO:2001110	biolink:NamedThing	negative regulation of lens epithelial cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation.	got7fsn_ti							yaf	2011-09-30T02:04:57Z						biological_process											owl:Class	
GO:0021599	biolink:NamedThing	abducens nerve formation	The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	got7fsn_ti	CN VI biosynthesis|CN VI formation													biological_process											owl:Class	
GO:0120234	biolink:NamedThing	stereocilium coat	A glycocalyx on the the endolymphatic surface of a cochlear hair cell that coats the external surface of each stereocilium and maintains a small distance between adjacent stereocilia in the bundle.	got7fsn_ti	stereocilium glycocalyx|auditory hair cell glycocalyx	https://github.com/geneontology/go-ontology/issues/19782					krc	2020-07-15T00:56:35Z						cellular_component											owl:Class	
GO:0015547	biolink:NamedThing	nalidixic acid transmembrane transporter activity	Enables the transfer of nalidixic acid from one side of a membrane to the other. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.	got7fsn_ti	nalidixic acid transporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0015896	biolink:NamedThing	nalidixic acid transport	The directed movement of nalidixic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.	got7fsn_ti														biological_process											owl:Class	
GO:0072192	biolink:NamedThing	ureter epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter.	got7fsn_ti							mah	2010-03-01T01:53:17Z						biological_process											owl:Class	
GO:0001928	biolink:NamedThing	regulation of exocyst assembly	Any process that modulates the frequency, rate or extent of exocyst assembly.	got7fsn_ti					Note that the assembly is regulated by several small GTPases of the Rab and Rho families.									biological_process											owl:Class	
GO:0016595	biolink:NamedThing	glutamate binding	Binding to glutamate, the anion of 2-aminopentanedioic acid.	got7fsn_ti	glutamic acid binding													molecular_function											owl:Class	
GO:0044201	biolink:NamedThing	host cell nuclear inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.	got7fsn_ti							jl	2009-10-21T11:08:33Z						cellular_component											owl:Class	
GO:0009324	biolink:NamedThing	D-amino-acid dehydrogenase complex	A protein complex that possesses D-amino-acid dehydrogenase activity.	got7fsn_ti					See also the molecular function term 'D-amino-acid oxidase activity ; GO:0003884'.									cellular_component											owl:Class	
GO:0016014	biolink:NamedThing	dystrobrevin complex	A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0000041	biolink:NamedThing	transition metal ion transport	The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	got7fsn_ti	transition metal transport													biological_process											owl:Class	
GO:1902755	biolink:NamedThing	sulfurated eukaryotic molybdenum cofactor(2-) metabolic process	The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-).	got7fsn_ti	sulfurated eukaryotic molybdenum cofactor(2-) metabolism						dph	2014-03-05T23:29:13Z						biological_process											owl:Class	
GO:0005697	biolink:NamedThing	telomerase holoenzyme complex	Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.	got7fsn_ti														cellular_component											owl:Class	
CHEBI:24834	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008258	biolink:NamedThing	head involution	Movement of the anterior ectoderm to the interior of the embryo.	got7fsn_ti														biological_process											owl:Class	
GO:0030015	biolink:NamedThing	CCR4-NOT core complex	The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.	got7fsn_ti														cellular_component											owl:Class	
GO:0005310	biolink:NamedThing	dicarboxylic acid transmembrane transporter activity	Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.	got7fsn_ti	dicarboxylate carrier|sodium:dicarboxylate/tricarboxylate symporter activity|dicarboxylic acid permease activity|dicarboxylate (succinate/fumarate/malate) antiporter activity										GO:0005312|GO:0015365	Reactome:R-HSA-1614546|Reactome:R-HSA-372843		molecular_function											owl:Class	
GO:0006835	biolink:NamedThing	dicarboxylic acid transport	The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	sodium:dicarboxylate transport										GO:0006841			biological_process											owl:Class	
GO:0106021	biolink:NamedThing	negative regulation of vesicle docking	Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking.	got7fsn_ti	negative regulation of vesicle to membrane docking						hjd	2017-05-16T14:05:29Z						biological_process											owl:Class	
GO:0035027	biolink:NamedThing	leading edge cell fate commitment	The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet.	got7fsn_ti														biological_process											owl:Class	
GO:1903543	biolink:NamedThing	positive regulation of exosomal secretion	Any process that activates or increases the frequency, rate or extent of exosomal secretion.	got7fsn_ti	up regulation of secretion of exosome|up regulation of exosomal protein secretion|up-regulation of secretion of exosome|up-regulation of exosomal secretion|activation of exosomal secretory pathway|activation of extracellular vesicular exosome secretion|up-regulation of extracellular vesicular exosome secretion|positive regulation of extracellular vesicular exosome secretion|activation of exosomal secretion|up-regulation of exosomal protein secretion|up regulation of extracellular vesicular exosome secretion|upregulation of exosomal protein secretion|upregulation of exosomal secretion|up regulation of exosomal secretory pathway|positive regulation of secretion of exosome|activation of exosomal protein secretion|positive regulation of exosomal secretory pathway|positive regulation of exosomal protein secretion|upregulation of secretion of exosome|upregulation of exosomal secretory pathway|up regulation of exosomal secretion|activation of secretion of exosome|upregulation of extracellular vesicular exosome secretion|up-regulation of exosomal secretory pathway						pga	2014-10-14T11:39:10Z						biological_process											owl:Class	
GO:0106024	biolink:NamedThing	negative regulation of pupariation	Any process that stops, prevents or reduces the rate of onset of pupariation.	got7fsn_ti							hjd	2017-05-24T19:35:29Z						biological_process											owl:Class	
CL:0000023	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045009	biolink:NamedThing	chitosome	An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.	got7fsn_ti														cellular_component											owl:Class	
GO:0031151	biolink:NamedThing	histone methyltransferase activity (H3-K79 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein.	got7fsn_ti	histone lysine N-methyltransferase activity (H3-K79 specific)|histone methylase activity (H3-K79 specific)													molecular_function											owl:Class	
CL:0002369	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903097	biolink:NamedThing	regulation of CENP-A containing nucleosome assembly	Any process that modulates the rate, frequency or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.	got7fsn_ti	regulation of centromere-specific nucleosome assembly|regulation of CENP-A loading|regulation of centromere-specific histone exchange|regulation of DNA replication-independent nucleosome assembly at centromere|regulation of centromere specific nucleosome exchange|regulation of CenH3-containing nucleosome assembly at centromere|regulation of CENP-A deposition|regulation of centromeric DNA replication-independent nucleosome assembly						vw	2014-06-03T16:15:30Z						biological_process											owl:Class	
GO:2000470	biolink:NamedThing	positive regulation of peroxidase activity	Any process that activates or increases the frequency, rate or extent of peroxidase activity.	got7fsn_ti	positive regulation of peroxidase reaction|positive regulation of oxyperoxidase activity|positive regulation of donor:hydrogen-peroxide oxidoreductase activity						bf	2011-03-08T02:19:25Z						biological_process											owl:Class	
GO:0060339	biolink:NamedThing	negative regulation of type I interferon-mediated signaling pathway	Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.	got7fsn_ti	negative regulation of type I interferon-mediated signalling pathway													biological_process											owl:Class	
GO:1902121	biolink:NamedThing	lithocholic acid binding	Binding to lithocholic acid.	got7fsn_ti	LCA binding						bf	2013-05-15T16:05:12Z						molecular_function											owl:Class	
CL:0001031	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000327	biolink:NamedThing	lytic vacuole within protein storage vacuole	A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole.	got7fsn_ti														cellular_component											owl:Class	
GO:1903432	biolink:NamedThing	regulation of TORC1 signaling	Any process that modulates the frequency, rate or extent of TORC1 signaling.	got7fsn_ti	regulation of TORC1 signal transduction						jl	2014-09-15T13:35:39Z						biological_process											owl:Class	
GO:0030208	biolink:NamedThing	dermatan sulfate biosynthetic process	The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.	got7fsn_ti	dermatan sulfate anabolism|dermatan sulfate formation|dermatan sulphate biosynthesis|chondroitin sulfate B biosynthesis|dermatan sulfate biosynthesis|dermatan sulfate synthesis|dermatan sulphate biosynthetic process|chondroitin sulfate B biosynthetic process													biological_process											owl:Class	
GO:0050651	biolink:NamedThing	dermatan sulfate proteoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.	got7fsn_ti	dermatan sulfate proteoglycan synthesis|chondroitin sulfate B proteoglycan biosynthetic process|dermatan sulfate proteoglycan anabolism|dermatan sulphate proteoglycan biosynthesis|dermatan sulfate proteoglycan formation|dermatan sulfate proteoglycan biosynthesis|dermatan sulphate proteoglycan biosynthetic process|chondroitin sulfate B proteoglycan biosynthesis													biological_process											owl:Class	
GO:0010705	biolink:NamedThing	meiotic DNA double-strand break processing involved in reciprocal meiotic recombination	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.	got7fsn_ti														biological_process											owl:Class	
GO:1904848	biolink:NamedThing	negative regulation of cell chemotaxis to fibroblast growth factor	Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.	got7fsn_ti	downregulation of cell chemotaxis to fibroblast growth factor|inhibition of cell chemotaxis to fibroblast growth factor|down regulation of cell chemotaxis to fibroblast growth factor|down-regulation of cell chemotaxis to fibroblast growth factor						rph	2015-12-10T12:04:08Z						biological_process											owl:Class	
GO:0004861	biolink:NamedThing	cyclin-dependent protein serine/threonine kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.	got7fsn_ti	cyclin dependent kinase inhibitor|cyclin dependent protein kinase inhibitor activity|cyclin-dependent kinase inhibitor|CDK inhibitor|cyclin-dependent protein kinase inhibitor activity											Reactome:R-HSA-69562|Reactome:R-HSA-187934		molecular_function											owl:Class	
GO:0034223	biolink:NamedThing	regulation of ascospore wall chitin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin.	got7fsn_ti	regulation of ascospore wall chitin biosynthesis|regulation of ascospore wall chitin formation|regulation of ascospore wall chitin synthesis|regulation of ascospore wall chitin anabolism													biological_process											owl:Class	
GO:0070237	biolink:NamedThing	positive regulation of activation-induced cell death of T cells	Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.	got7fsn_ti	up-regulation of activation-induced cell death of T cells|positive regulation of activation-induced cell death of T-lymphocytes|up regulation of activation-induced cell death of T cells|positive regulation of AICD|activation of activation-induced cell death of T cells|positive regulation of activated T cell apoptosis|stimulation of activation-induced cell death of T cells|upregulation of activation-induced cell death of T cells|positive regulation of activation-induced cell death of T lymphocytes|positive regulation of antigen-driven apoptosis|positive regulation of activation-induced cell death of T-cells													biological_process											owl:Class	
CL:0008019	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905700	biolink:NamedThing	negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	negative regulation of xenobiotic transmembrane export|downregulation of drug transmembrane export|down-regulation of drug transmembrane export|down regulation of drug transmembrane export|negative regulation of drug transmembrane export|inhibition of drug transmembrane export	https://github.com/geneontology/go-ontology/issues/19460|https://github.com/geneontology/go-ontology/issues/17083					sl	2016-11-15T16:46:36Z						biological_process											owl:Class	
CHEBI:33708	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030910	biolink:NamedThing	olfactory placode formation	The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.	got7fsn_ti														biological_process											owl:Class	
GO:1901389	biolink:NamedThing	negative regulation of transforming growth factor beta activation	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation.	got7fsn_ti	downregulation of transforming growth factor beta activation|down-regulation of TGFbeta activation|inhibition of TGFbeta activation|down-regulation of TGF-beta activation|down-regulation of transforming growth factor beta activation|negative regulation of TGF-B activation|downregulation of TGFbeta activation|inhibition of TGFB activation|downregulation of TGF-B activation|negative regulation of TGFB activation|downregulation of TGFB activation|down regulation of TGFbeta activation|down-regulation of latent TGF-beta activation|down regulation of TGFB activation|inhibition of transforming growth factor beta activation|negative regulation of latent TGF-beta activation|downregulation of TGF-beta activation|inhibition of TGF-B activation|down-regulation of TGF-B activation|down regulation of latent TGF-beta activation|downregulation of latent TGF-beta activation|inhibition of latent TGF-beta activation|negative regulation of TGF-beta activation|down regulation of transforming growth factor beta activation|downregulation of L-TGF-beta activation|down-regulation of TGFB activation|down regulation of TGF-B activation|inhibition of L-TGF-beta activation|negative regulation of TGFbeta activation|down regulation of L-TGF-beta activation|inhibition of TGF-beta activation|down-regulation of L-TGF-beta activation|down regulation of TGF-beta activation|negative regulation of L-TGF-beta activation						bf	2012-10-01T10:33:09Z						biological_process											owl:Class	
GO:0060702	biolink:NamedThing	negative regulation of endoribonuclease activity	Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.	got7fsn_ti							dph	2009-06-08T02:52:27Z						biological_process											owl:Class	
GO:1903637	biolink:NamedThing	negative regulation of protein insertion into mitochondrial outer membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane.	got7fsn_ti	down-regulation of protein transport into mitochondrial outer membrane|down-regulation of mitochondrial outer membrane protein import|down-regulation of protein insertion into mitochondrial outer membrane|downregulation of protein insertion into mitochondrial outer membrane|negative regulation of protein transport into mitochondrial outer membrane|inhibition of mitochondrial outer membrane protein import|downregulation of mitochondrial outer membrane protein import|down regulation of protein insertion into mitochondrial outer membrane|inhibition of protein import into mitochondrial outer membrane|downregulation of protein import into mitochondrial outer membrane|down regulation of protein transport into mitochondrial outer membrane|negative regulation of mitochondrial outer membrane protein import|down-regulation of protein import into mitochondrial outer membrane|down regulation of protein import into mitochondrial outer membrane|inhibition of protein insertion into mitochondrial outer membrane|negative regulation of protein import into mitochondrial outer membrane|down regulation of mitochondrial outer membrane protein import|downregulation of protein transport into mitochondrial outer membrane|inhibition of protein transport into mitochondrial outer membrane						pga	2014-11-20T15:54:53Z						biological_process											owl:Class	
GO:2000729	biolink:NamedThing	positive regulation of mesenchymal cell proliferation involved in ureter development	Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development.	got7fsn_ti	positive regulation of ureter mesenchymal cell proliferation|positive regulation of ureteral mesenchymal cell proliferation						yaf	2011-06-10T02:27:19Z						biological_process											owl:Class	
PO:0009073	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903007	biolink:NamedThing	positive regulation of Lys63-specific deubiquitinase activity	Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity.	got7fsn_ti	up regulation of Lys63-specific deubiquitinase activity|upregulation of Lys63-specific deubiquitinase activity|up-regulation of Lys63-specific deubiquitinase activity|activation of Lys63-specific deubiquitinase activity						bf	2014-05-12T15:47:35Z						biological_process											owl:Class	
GO:0033162	biolink:NamedThing	melanosome membrane	The lipid bilayer surrounding a melanosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0120125	biolink:NamedThing	PNGase complex	A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.	got7fsn_ti							krc	2018-02-12T16:31:57Z						cellular_component											owl:Class	
GO:0035977	biolink:NamedThing	protein deglycosylation involved in glycoprotein catabolic process	The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein.	got7fsn_ti							bf	2011-08-18T10:31:23Z						biological_process											owl:Class	
GO:0010329	biolink:NamedThing	auxin efflux transmembrane transporter activity	Enables the transfer of auxin, from one side of a membrane to the other, out of a cell.	got7fsn_ti	auxin efflux facilitator|auxin efflux carrier													molecular_function											owl:Class	
GO:1904174	biolink:NamedThing	negative regulation of histone demethylase activity (H3-K4 specific)	Any process that stops, prevents or reduces the frequency, rate or extent of histone demethylase activity (H3-K4 specific).	got7fsn_ti	down regulation of histone demethylase activity (H3-K4 specific)|downregulation of histone demethylase activity (H3-K4 specific)|inhibition of histone demethylase activity (H3-K4 specific)|down-regulation of histone demethylase activity (H3-K4 specific)						dph	2015-04-24T19:29:38Z						biological_process											owl:Class	
GO:0045688	biolink:NamedThing	regulation of antipodal cell differentiation	Any process that modulates the frequency, rate or extent of antipodal cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0033618	biolink:NamedThing	plasma membrane respiratory chain complex IV assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane.	got7fsn_ti	plasma membrane cytochrome c oxidase biogenesis|plasma membrane cytochrome c oxidase complex assembly													biological_process											owl:Class	
GO:1903206	biolink:NamedThing	negative regulation of hydrogen peroxide-induced cell death	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced cell death.	got7fsn_ti	down regulation of cell death in response to H2O2|inhibition of cell death in response to H2O2|negative regulation of hydrogen peroxide-mediated cell death|negative regulation of cell death in response to hydrogen peroxide|inhibition of hydrogen peroxide-mediated cell death|down-regulation of hydrogen peroxide-mediated cell death|protection against hydrogen peroxide-induced cell death|downregulation of cell death in response to H2O2|down regulation of hydrogen peroxide-mediated cell death|inhibition of cell death in response to hydrogen peroxide|down regulation of cell death in response to hydrogen peroxide|downregulation of cell death in response to hydrogen peroxide|downregulation of hydrogen peroxide-mediated cell death|negative regulation of cell death in response to H2O2|protection against H2O2-induced cell death|down-regulation of cell death in response to hydrogen peroxide|down-regulation of cell death in response to H2O2						bf	2014-07-21T16:21:53Z						biological_process											owl:Class	
GO:1901045	biolink:NamedThing	negative regulation of oviposition	Any process that stops, prevents or reduces the frequency, rate or extent of oviposition.	got7fsn_ti	downregulation of oviposition|negative regulation of egg laying|down regulation of egg-laying|negative regulation of egg-laying|down-regulation of egg laying|down-regulation of egg-laying|down-regulation of oviposition|downregulation of egg laying|inhibition of egg laying|down regulation of egg laying|downregulation of egg-laying|down regulation of oviposition|inhibition of egg-laying|inhibition of oviposition						kmv	2012-06-27T06:19:58Z						biological_process											owl:Class	
GO:0051759	biolink:NamedThing	sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation	The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II.	got7fsn_ti	sister chromosome movement towards spindle pole during meiosis II|meiosis II, sister chromosome movement towards spindle pole													biological_process											owl:Class	
GO:0098640	biolink:NamedThing	integrin binding involved in cell-matrix adhesion	Any integrin binding that occurs as part of the process of cell-matrix adhesion.	got7fsn_ti														molecular_function											owl:Class	
GO:0008191	biolink:NamedThing	metalloendopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.	got7fsn_ti	metalloproteinase inhibitor|metalloprotease inhibitor													molecular_function											owl:Class	
CHEBI:15986	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000202	biolink:NamedThing	positive regulation of ribosomal subunit export from nucleus	Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus.	got7fsn_ti	positive regulation of ribosomal subunit-nucleus export|positive regulation of ribosomal subunit export from cell nucleus|positive regulation of ribosomal subunit export out of nucleus|positive regulation of ribosomal subunit transport from nucleus to cytoplasm|positive regulation of ribosome export from nucleus						mah	2010-10-26T10:44:36Z						biological_process											owl:Class	
GO:0001960	biolink:NamedThing	negative regulation of cytokine-mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.	got7fsn_ti	down-regulation of cytokine mediated signaling pathway|downregulation of cytokine mediated signaling pathway|inhibition of cytokine mediated signaling pathway|down regulation of cytokine mediated signaling pathway|negative regulation of cytokine mediated signalling pathway|negative regulation of cytokine mediated signaling pathway|negative regulation of cytokine and chemokine mediated signaling pathway													biological_process											owl:Class	
GO:0031315	biolink:NamedThing	extrinsic component of mitochondrial outer membrane	The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic to mitochondrial outer membrane													cellular_component											owl:Class	
GO:0030178	biolink:NamedThing	negative regulation of Wnt signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.	got7fsn_ti	down-regulation of frizzled signaling pathway|inhibition of Wnt receptor signaling pathway|inhibition of frizzled signaling pathway|down-regulation of Wnt receptor signaling pathway|down regulation of Wnt receptor signaling pathway|negative regulation of frizzled signaling pathway|downregulation of Wnt receptor signaling pathway|negative regulation of frizzled signalling pathway|negative regulation of Wnt receptor signaling pathway|downregulation of frizzled signaling pathway|negative regulation of Wnt receptor signalling pathway|down regulation of frizzled signaling pathway|negative regulation of Wnt-activated signaling pathway										GO:0045810			biological_process											owl:Class	
GO:0072253	biolink:NamedThing	metanephric juxtaglomerulus cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell.	got7fsn_ti							mah	2010-03-19T03:55:47Z						biological_process											owl:Class	
GO:0045692	biolink:NamedThing	negative regulation of embryo sac central cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation.	got7fsn_ti	down-regulation of female gametophyte central cell differentiation|negative regulation of female gametophyte central cell differentiation|inhibition of female gametophyte central cell differentiation|down regulation of female gametophyte central cell differentiation|downregulation of female gametophyte central cell differentiation													biological_process											owl:Class	
GO:0015152	biolink:NamedThing	glucose-6-phosphate transmembrane transporter activity	Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.	got7fsn_ti														molecular_function											owl:Class	
GO:0015760	biolink:NamedThing	glucose-6-phosphate transport	The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.	got7fsn_ti														biological_process											owl:Class	
GO:0086087	biolink:NamedThing	voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti							dph	2011-11-22T01:30:20Z						molecular_function											owl:Class	
GO:0086050	biolink:NamedThing	membrane repolarization during bundle of His cell action potential	The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	got7fsn_ti	membrane repolarization during bundle of His cardiac muscle cell action potential						dph	2011-11-16T11:50:41Z						biological_process											owl:Class	
GO:0048012	biolink:NamedThing	hepatocyte growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands.	got7fsn_ti	HGF receptor signaling pathway|HGF receptor signalling pathway|Met signaling pathway													biological_process											owl:Class	
GO:1904255	biolink:NamedThing	negative regulation of iron ion transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity.	got7fsn_ti	down regulation of iron cation channel activity|down-regulation of iron cation channel activity|negative regulation of iron-specific channel activity|downregulation of iron cation channel activity|inhibition of iron cation channel activity|negative regulation of iron channel activity|down regulation of iron-specific channel activity|negative regulation of iron cation channel activity|inhibition of iron channel activity|down regulation of iron channel activity|down-regulation of iron channel activity|downregulation of iron channel activity|downregulation of iron-specific channel activity|inhibition of iron-specific channel activity|down-regulation of iron-specific channel activity						kom	2015-05-20T14:05:06Z						biological_process											owl:Class	
GO:1904602	biolink:NamedThing	serotonin-activated cation-selective channel complex	A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.	got7fsn_ti	5-HT3 receptor complex|serotonin receptor complex|5-hydroxytryptamine receptor 3 complex|5-HT-3 receptor complex|5HT3 receptor complex	https://github.com/geneontology/go-ontology/issues/12942			An example of this is HTR3A in human (P46098) in PMID:16116092 (inferred from direct assay).		bhm	2015-08-26T13:19:49Z						cellular_component											owl:Class	
GO:2000732	biolink:NamedThing	positive regulation of termination of RNA polymerase I transcription	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription.	got7fsn_ti	positive regulation of transcription termination from RNA polymerase I promoter|positive regulation of transcription termination from Pol I promoter|positive regulation of RNA polymerase I transcription termination						dph	2011-06-10T08:43:48Z						biological_process											owl:Class	
GO:0006761	biolink:NamedThing	dihydrofolate biosynthetic process	The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate.	got7fsn_ti	7,8-dihydrofolate biosynthesis|dihydrofolate biosynthesis|7,8-dihydrofolate biosynthetic process|dihydrofolate formation|dihydrofolate anabolism|dihydrofolate synthesis													biological_process											owl:Class	
GO:0042879	biolink:NamedThing	aldonate transmembrane transporter activity	Enables the transfer of aldonate from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042873	biolink:NamedThing	aldonate transmembrane transport	The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	aldonate transport													biological_process											owl:Class	
GO:0031246	biolink:NamedThing	intrinsic component of periplasmic side of cell outer membrane	The component of the cell outer membrane consisting of the gene products that that penetrate the periplasmic side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor.	got7fsn_ti	intrinsic to external side of cell outer membrane|intrinsic to internal side of outer membrane|intrinsic to internal side of cell outer membrane|intrinsic to internal leaflet of cell outer membrane													cellular_component											owl:Class	
GO:1901375	biolink:NamedThing	acetate ester transmembrane transporter activity	Enables the transfer of an acetate ester from one side of a membrane to the other.	got7fsn_ti							bf	2012-09-28T10:47:08Z						molecular_function											owl:Class	
GO:1901374	biolink:NamedThing	acetate ester transport	The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							bf	2012-09-28T10:42:13Z						biological_process											owl:Class	
GO:0000936	biolink:NamedThing	primary cell septum	A cell septum that forms following nuclear division.	got7fsn_ti	primary septum													cellular_component											owl:Class	
GO:0110111	biolink:NamedThing	negative regulation of animal organ morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.	got7fsn_ti							kmv	2018-07-05T14:25:21Z						biological_process											owl:Class	
GO:0048013	biolink:NamedThing	ephrin receptor signaling pathway	The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.	got7fsn_ti	Eph receptor signalling pathway|Eph receptor signaling pathway													biological_process											owl:Class	
GO:0090406	biolink:NamedThing	pollen tube	A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.	got7fsn_ti					Carries the male gametes to into or near the ovule. May be branched in gymnosperms. This term replaces the obsolete term PO:0006345. Part of pollen tube cell (PO:0025195).		tb	2011-01-10T01:59:40Z						cellular_component											owl:Class	
GO:1902796	biolink:NamedThing	regulation of snoRNA processing	Any process that modulates the frequency, rate or extent of snoRNA processing.	got7fsn_ti							mah	2014-03-24T12:47:02Z						biological_process											owl:Class	
GO:0072005	biolink:NamedThing	maintenance of kidney identity	The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti	maintenance of kidney anlage identity						mah	2010-01-25T11:57:41Z						biological_process											owl:Class	
GO:0015160	biolink:NamedThing	beta-glucan transmembrane transporter activity	Enables the transfer of beta-glucans from one side of a membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.	got7fsn_ti														molecular_function											owl:Class	
GO:1903826	biolink:NamedThing	arginine transmembrane transport	The directed movement of arginine across a membrane.	got7fsn_ti							vw	2015-01-20T10:38:15Z						biological_process											owl:Class	
GO:1905451	biolink:NamedThing	positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.	got7fsn_ti	up regulation of Fcgamma receptor-mediated phagocytosis|upregulation of Fcgamma receptor-mediated phagocytosis|activation of Fcgamma receptor-mediated phagocytosis|up-regulation of Fcgamma receptor-mediated phagocytosis|activation of IgG-mediated phagocytosis|positive regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|up regulation of Fc gamma receptor-dependent phagocytosis|up regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|positive regulation of IgG-mediated phagocytosis|upregulation of Fc-gamma receptor signalling pathway involved in phagocytosis|up-regulation of Fc gamma receptor-dependent phagocytosis|up regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|activation of Fc-gamma receptor signalling pathway involved in phagocytosis|up-regulation of IgG-mediated phagocytosis|upregulation of Fc gamma receptor-dependent phagocytosis|up regulation of IgG-mediated phagocytosis|positive regulation of Fcgamma receptor-mediated phagocytosis|activation of Fc-gamma receptor signaling pathway involved in phagocytosis|up-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|positive regulation of Fc gamma receptor-dependent phagocytosis|upregulation of Fc-gamma receptor signaling pathway involved in phagocytosis|upregulation of IgG-mediated phagocytosis|up-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|activation of Fc gamma receptor-dependent phagocytosis						sl	2016-09-15T19:42:06Z						biological_process											owl:Class	
GO:0051978	biolink:NamedThing	lysophospholipid:sodium symporter activity	Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.	got7fsn_ti	lysophospholipid transporter activity	https://github.com/geneontology/go-ontology/issues/17207												molecular_function											owl:Class	
GO:0051977	biolink:NamedThing	lysophospholipid transport	The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.	got7fsn_ti														biological_process											owl:Class	
GO:1903710	biolink:NamedThing	spermine transmembrane transport	The process in which spermine is transported across a membrane.	got7fsn_ti							vw	2014-12-06T08:11:32Z						biological_process											owl:Class	
GO:0014835	biolink:NamedThing	myoblast differentiation involved in skeletal muscle regeneration	The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:1905880	biolink:NamedThing	negative regulation of oogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis.	got7fsn_ti	down-regulation of oogenesis|downregulation of oogenesis|down-regulation of ovum development|inhibition of oogenesis|inhibition of ovum development|down regulation of ovum development|negative regulation of ovum development|down regulation of oogenesis|downregulation of ovum development						hbye	2017-01-31T09:31:15Z						biological_process											owl:Class	
GO:0048913	biolink:NamedThing	anterior lateral line nerve glial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:0007382	biolink:NamedThing	specification of segmental identity, maxillary segment	The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	got7fsn_ti					See also the fly_anatomy.ontology term 'maxillary segment ; FBbt:00000013'.									biological_process											owl:Class	
GO:0032968	biolink:NamedThing	positive regulation of transcription elongation from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.	got7fsn_ti	positive regulation of gene-specific transcription elongation from RNA polymerase II promoter|positive regulation of RNA elongation from RNA polymerase II promoter										GO:0090040			biological_process											owl:Class	
GO:0061753	biolink:NamedThing	substrate localization to autophagosome	The localization process by which an autophagic substrate is delivered to a forming autophagosome.	got7fsn_ti	substrate sequestration to phagophore|substrate sequestration to autophagosome						dph	2015-11-20T11:14:22Z						biological_process											owl:Class	
GO:0061297	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.	got7fsn_ti	positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis						dph	2010-09-06T09:58:59Z						biological_process											owl:Class	
GO:1903438	biolink:NamedThing	positive regulation of mitotic cytokinetic process	Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process.	got7fsn_ti	activation of mitotic cytokinetic process|upregulation of mitotic cytokinetic process|up-regulation of mitotic cytokinetic process|up regulation of mitotic cytokinetic process						tb	2014-09-15T23:11:55Z						biological_process											owl:Class	
CHEBI:67194	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061930	biolink:NamedThing	regulation of erythrocyte enucleation	Any process that modulates the frequency, rate or extent of erythrocyte enucleation.	got7fsn_ti							dph	2017-09-05T12:48:05Z						biological_process											owl:Class	
GO:0019805	biolink:NamedThing	quinolinate biosynthetic process	The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.	got7fsn_ti	quinolinate formation|quinolinate biosynthesis|quinolinate anabolism|quinolinate synthesis													biological_process											owl:Class	
GO:0032833	biolink:NamedThing	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.	got7fsn_ti	downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0007558	biolink:NamedThing	regulation of juvenile hormone secretion	Any process that modulates the frequency, rate or extent of juvenile hormone secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0007284	biolink:NamedThing	spermatogonial cell division	The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes).	got7fsn_ti	spermatogonium division				See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'.									biological_process											owl:Class	
GO:0006122	biolink:NamedThing	mitochondrial electron transport, ubiquinol to cytochrome c	The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III.	got7fsn_ti	complex III (ubiquinone to cytochrome c)													biological_process											owl:Class	
GO:0099631	biolink:NamedThing	postsynaptic endocytic zone cytoplasmic component	The cytoplasmic component of the postsynaptic endocytic zone.	got7fsn_ti	postsynaptic endocytic zone cytoplasmic component													cellular_component											owl:Class	
GO:1902672	biolink:NamedThing	right anterior basal body	Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage).	got7fsn_ti	microtubule basal body of right anterior flagellum|ciliary basal body of right anterior flagellum|cilial basal body of right anterior cilium|cilium basal body of right anterior flagellum|ciliary basal body of right anterior cilium|right anterior flagellum ciliary basal body|cilial basal body of right anterior flagellum|microtubule basal body of right anterior cilium|cilium basal body of right anterior cilium				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:46:26Z						cellular_component											owl:Class	
GO:0015607	biolink:NamedThing	ABC-type fatty-acyl-CoA transporter activity	Catalysis of the reaction ATP + H(2)O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.	got7fsn_ti	ABC-type fatty-acyl-CoA transporter|fatty-acyl-CoA transmembrane transporter activity|fatty acyl CoA transporter activity|fatty-acyl-CoA-transporting ATPase|ATPase-coupled fatty-acyl-CoA transmembrane transporter activity											RHEA:15181|EC:7.6.2.4		molecular_function											owl:Class	
GO:0015916	biolink:NamedThing	fatty-acyl-CoA transport	The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A).	got7fsn_ti	fatty acyl-CoA transport|fatty acyl CoA transport|fatty acyl coenzyme A transport													biological_process											owl:Class	
GO:1901974	biolink:NamedThing	glycerate transmembrane transporter activity	Enables the transfer of glycerate from one side of a membrane to the other.	got7fsn_ti							ms	2013-03-05T16:48:45Z						molecular_function											owl:Class	
GO:1901975	biolink:NamedThing	glycerate transmembrane transport	The process in which glycerate is transported across a membrane.	got7fsn_ti							ms	2013-03-05T16:48:50Z						biological_process											owl:Class	
GO:0015166	biolink:NamedThing	polyol transmembrane transporter activity	Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol.	got7fsn_ti	sugar/polyol channel activity											Reactome:R-HSA-429571		molecular_function											owl:Class	
GO:0015791	biolink:NamedThing	polyol transport	The directed movement of polyols, any polyhydric alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0033154	biolink:NamedThing	ABC-type oligogalacturonide transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).	got7fsn_ti	oligogalacturonide-transporting ATPase activity|oligogalacturonide transmembrane transporter activity|ATP-dependent oligogalacturonide transmembrane transporter activity|ATPase-coupled oligogalacturonide transmembrane transporter activity|oligogalacturonide transporting ATPase activity										GO:0033155	TC:3.A.1.1.11		molecular_function											owl:Class	
GO:0033156	biolink:NamedThing	oligogalacturonide transport	The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0015568	biolink:NamedThing	L-idonate transmembrane transporter activity	Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	got7fsn_ti	L-idonate/D-gluconate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0015726	biolink:NamedThing	L-idonate transmembrane transport	The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	got7fsn_ti	L-idonate transport													biological_process											owl:Class	
GO:0015107	biolink:NamedThing	chlorate transmembrane transporter activity	Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015702	biolink:NamedThing	chlorate transport	The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0110033	biolink:NamedThing	regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	got7fsn_ti	regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway						kmv	2017-07-17T20:22:20Z						biological_process											owl:Class	
GO:0015795	biolink:NamedThing	sorbitol transport	The directed movement of sorbitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.	got7fsn_ti	glucitol transport													biological_process											owl:Class	
GO:0034315	biolink:NamedThing	regulation of Arp2/3 complex-mediated actin nucleation	Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0086088	biolink:NamedThing	voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti							dph	2011-11-22T01:32:02Z						molecular_function											owl:Class	
GO:0086051	biolink:NamedThing	membrane repolarization during Purkinje myocyte action potential	The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	got7fsn_ti							dph	2011-11-16T11:51:56Z						biological_process											owl:Class	
GO:0071451	biolink:NamedThing	cellular response to superoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.	got7fsn_ti							mah	2009-12-16T04:39:14Z						biological_process											owl:Class	
UBERON:0002036	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060579	biolink:NamedThing	ventral spinal cord interneuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.	got7fsn_ti							dph	2009-05-07T12:21:13Z						biological_process											owl:Class	
GO:0038147	biolink:NamedThing	C-X-C motif chemokine 12 receptor activity	Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	stromal cell-derived factor-1 receptor activity|CXCL12 receptor activity|SDF-1 receptor activity|CXCR7|CXCR4						bf	2012-05-11T11:32:53Z						molecular_function											owl:Class	
GO:0010968	biolink:NamedThing	regulation of microtubule nucleation	Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.	got7fsn_ti							tb	2009-05-20T11:51:21Z						biological_process											owl:Class	
CHEBI:16991	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097151	biolink:NamedThing	positive regulation of inhibitory postsynaptic potential	Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.	got7fsn_ti	positive regulation of inhibitory post-synaptic membrane potential|positive regulation of IPSP						pr	2011-08-12T10:07:45Z						biological_process											owl:Class	
GO:2000276	biolink:NamedThing	negative regulation of oxidative phosphorylation uncoupler activity	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity.	got7fsn_ti	negative regulation of mitochondrial uncoupling protein activity|negative regulation of uncoupling protein activity						mah	2010-12-07T12:14:59Z						biological_process											owl:Class	
GO:0071052	biolink:NamedThing	alpha9-beta1 integrin-ADAM1 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.	got7fsn_ti	ITGA9-ITGB1-ADAM1 complex						mah	2009-11-03T03:55:15Z						cellular_component											owl:Class	
GO:0003289	biolink:NamedThing	atrial septum primum morphogenesis	The process in which anatomical structure of an atrial septum primum is generated and organized.	got7fsn_ti							dph	2009-10-20T10:32:32Z						biological_process											owl:Class	
GO:0002867	biolink:NamedThing	regulation of B cell deletion	Any process that modulates the frequency, rate, or extent of B cell deletion.	got7fsn_ti	regulation of B lymphocyte deletion|regulation of B-cell deletion|regulation of B-lymphocyte deletion													biological_process											owl:Class	
GO:0002909	biolink:NamedThing	negative regulation of peripheral B cell deletion	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.	got7fsn_ti	down-regulation of peripheral B cell deletion|inhibition of peripheral B cell deletion|downregulation of peripheral B cell deletion|down regulation of peripheral B cell deletion													biological_process											owl:Class	
CHEBI:33569	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015835	biolink:NamedThing	peptidoglycan transport	The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	murein transport													biological_process											owl:Class	
GO:2001188	biolink:NamedThing	regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.	got7fsn_ti	regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell						yaf	2011-11-03T01:31:30Z						biological_process											owl:Class	
GO:0110161	biolink:NamedThing	positive regulation of mitotic spindle formation (spindle phase one)	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).	got7fsn_ti							kmv	2019-08-12T15:21:08Z						biological_process											owl:Class	
GO:0030150	biolink:NamedThing	protein import into mitochondrial matrix	The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.	got7fsn_ti	mitochondrial matrix protein import|mitochondrial translocation|protein transport into mitochondrial matrix													biological_process											owl:Class	
GO:0031382	biolink:NamedThing	mating projection formation	The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi.	got7fsn_ti	shmooing|mating projection assembly|mating projection biogenesis													biological_process											owl:Class	
GO:0070165	biolink:NamedThing	positive regulation of adiponectin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.	got7fsn_ti	up-regulation of adiponectin secretion|activation of adiponectin secretion|stimulation of adiponectin secretion|up regulation of adiponectin secretion|upregulation of adiponectin secretion													biological_process											owl:Class	
GO:0099628	biolink:NamedThing	neurotransmitter receptor diffusion trapping	The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0009339	biolink:NamedThing	glycolate oxidase complex	An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN).	got7fsn_ti														cellular_component											owl:Class	
GO:0140250	biolink:NamedThing	regulation protein catabolic process at synapse	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/204			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:34:56Z						biological_process											owl:Class	
GO:0140193	biolink:NamedThing	regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.	got7fsn_ti							pg	2018-02-15T19:08:49Z						biological_process											owl:Class	
GO:1903182	biolink:NamedThing	regulation of SUMO transferase activity	Any process that modulates the frequency, rate or extent of SUMO ligase activity.	got7fsn_ti	regulation of SMT3 conjugating enzyme|regulation of SUMO conjugating enzyme activity						bf	2014-07-14T14:01:40Z						biological_process											owl:Class	
GO:0048320	biolink:NamedThing	axial mesoderm formation	The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	got7fsn_ti														biological_process											owl:Class	
GO:0043159	biolink:NamedThing	acrosomal matrix	A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction.	got7fsn_ti														cellular_component											owl:Class	
GO:1902891	biolink:NamedThing	negative regulation of root hair elongation	Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation.	got7fsn_ti	down regulation of root hair elongation|inhibition of root hair elongation|downregulation of root hair elongation|down-regulation of root hair elongation						als	2014-04-07T13:46:47Z						biological_process											owl:Class	
GO:0071731	biolink:NamedThing	response to nitric oxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.	got7fsn_ti							mah	2010-03-17T04:03:38Z						biological_process											owl:Class	
GO:0035207	biolink:NamedThing	negative regulation of hemocyte proliferation	Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.	got7fsn_ti	inhibition of hemocyte proliferation|down-regulation of hemocyte proliferation|downregulation of hemocyte proliferation|negative regulation of arthropod blood cell proliferation|down regulation of hemocyte proliferation													biological_process											owl:Class	
GO:0034604	biolink:NamedThing	pyruvate dehydrogenase (NAD+) activity	Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH.	got7fsn_ti												RHEA:28042|KEGG_REACTION:R00209|MetaCyc:PYRUVDEH-RXN		molecular_function											owl:Class	
GO:0009358	biolink:NamedThing	polyphosphate kinase complex	A protein complex that possesses polyphosphate kinase activity.	got7fsn_ti					See also the molecular function term 'polyphosphate kinase activity ; GO:0008976'.									cellular_component											owl:Class	
GO:0021567	biolink:NamedThing	rhombomere 1 development	The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:1901679	biolink:NamedThing	nucleotide transmembrane transport	The directed movement of nucleotide across a membrane.	got7fsn_ti	nucleotide membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		pr	2012-11-22T15:43:23Z						biological_process											owl:Class	
GO:2001074	biolink:NamedThing	regulation of metanephric ureteric bud development	Any process that modulates the frequency, rate or extent of metanephric ureteric bud development.	got7fsn_ti							yaf	2011-09-14T01:11:06Z						biological_process											owl:Class	
GO:0071403	biolink:NamedThing	cellular response to high density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.	got7fsn_ti	response to high density lipoprotein particle stimulus|cellular response to high-density lipoprotein particle stimulus|response to high density lipoprotein particle						mah	2009-12-14T02:51:43Z			GO:0055099			biological_process											owl:Class	
GO:0015698	biolink:NamedThing	inorganic anion transport	The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.	got7fsn_ti														biological_process											owl:Class	
GO:1905450	biolink:NamedThing	negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.	got7fsn_ti	down-regulation of Fcgamma receptor-mediated phagocytosis|down regulation of Fc gamma receptor-dependent phagocytosis|negative regulation of IgG-mediated phagocytosis|downregulation of Fc-gamma receptor signalling pathway involved in phagocytosis|inhibition of Fc-gamma receptor signalling pathway involved in phagocytosis|down-regulation of Fc gamma receptor-dependent phagocytosis|down regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|inhibition of Fc gamma receptor-dependent phagocytosis|down regulation of Fcgamma receptor-mediated phagocytosis|downregulation of Fc gamma receptor-dependent phagocytosis|inhibition of IgG-mediated phagocytosis|down-regulation of IgG-mediated phagocytosis|down regulation of IgG-mediated phagocytosis|inhibition of Fcgamma receptor-mediated phagocytosis|down-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|negative regulation of Fc gamma receptor-dependent phagocytosis|downregulation of Fc-gamma receptor signaling pathway involved in phagocytosis|down regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|inhibition of Fc-gamma receptor signaling pathway involved in phagocytosis|downregulation of IgG-mediated phagocytosis|downregulation of Fcgamma receptor-mediated phagocytosis|negative regulation of Fcgamma receptor-mediated phagocytosis|negative regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|down-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis						sl	2016-09-15T19:41:58Z						biological_process											owl:Class	
GO:0045898	biolink:NamedThing	regulation of RNA polymerase II transcription preinitiation complex assembly	Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.	got7fsn_ti	regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|regulation of RNA polymerase II transcriptional pre-initiation complex assembly|regulation of RNA polymerase II transcriptional preinitiation complex formation|regulation of RNA polymerase II transcriptional preinitiation complex assembly													biological_process											owl:Class	
GO:0015434	biolink:NamedThing	ABC-type cadmium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole).	got7fsn_ti	ATPase-coupled cadmium transmembrane transporter activity|cadmium ABC transporter|cadmium-transporting ATPase activity|ATP-dependent cadmium transmembrane transporter activity											EC:7.2.2.2|MetaCyc:3.6.3.46-RXN		molecular_function											owl:Class	
GO:0070574	biolink:NamedThing	cadmium ion transmembrane transport	A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	transmembrane cadmium transport|cadmium ion membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-04-20T03:31:47Z						biological_process											owl:Class	
GO:0043020	biolink:NamedThing	NADPH oxidase complex	A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.	got7fsn_ti	flavocytochrome b558|respiratory-burst oxidase													cellular_component											owl:Class	
GO:0070778	biolink:NamedThing	L-aspartate transmembrane transport	The directed movement of L-aspartate across a membrane.	got7fsn_ti	L-aspartate transport						mah	2009-07-02T01:46:31Z			GO:0089712			biological_process											owl:Class	
GO:0072304	biolink:NamedThing	regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.	got7fsn_ti	regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis						mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:0071114	biolink:NamedThing	alphaV-beta3 integrin-tumstatin complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.	got7fsn_ti	ITGAV-ITGB3-COL4A3 complex						mah	2009-11-13T02:18:29Z						cellular_component											owl:Class	
GO:1901969	biolink:NamedThing	positive regulation of polynucleotide 3'-phosphatase activity	Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity.	got7fsn_ti	up-regulation of polynucleotide 3'-phosphatase activity|activation of deoxyribonucleate 3'-phosphatase activity|up-regulation of deoxyribonucleate 3'-phosphatase activity|upregulation of 2'(3')-polynucleotidase activity|activation of DNA 3'-phosphatase activity|up-regulation of 5'-polynucleotidekinase 3'-phosphatase activity|up regulation of 2'(3')-polynucleotidase activity|up-regulation of 2'(3')-polynucleotidase activity|positive regulation of 5'-polynucleotidekinase 3'-phosphatase activity|activation of 2'(3')-polynucleotidase activity|positive regulation of deoxyribonucleate 3'-phosphatase activity|upregulation of polynucleotide 3'-phosphatase activity|upregulation of polynucleotide 3'-phosphohydrolase activity|positive regulation of 2'(3')-polynucleotidase activity|positive regulation of DNA 3'-phosphatase activity|positive regulation of polynucleotide 3'-phosphohydrolase activity|up regulation of deoxyribonucleate 3'-phosphatase activity|activation of polynucleotide 3'-phosphohydrolase activity|activation of 5'-polynucleotidekinase 3'-phosphatase activity|up regulation of DNA 3'-phosphatase activity|up-regulation of polynucleotide 3'-phosphohydrolase activity|up regulation of polynucleotide 3'-phosphatase activity|upregulation of 5'-polynucleotidekinase 3'-phosphatase activity|up regulation of 5'-polynucleotidekinase 3'-phosphatase activity|activation of polynucleotide 3'-phosphatase activity|up-regulation of DNA 3'-phosphatase activity|upregulation of DNA 3'-phosphatase activity|upregulation of deoxyribonucleate 3'-phosphatase activity|up regulation of polynucleotide 3'-phosphohydrolase activity						tb	2013-02-22T00:58:31Z						biological_process											owl:Class	
GO:0007390	biolink:NamedThing	germ-band shortening	The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.	got7fsn_ti	germ-band retraction													biological_process											owl:Class	
GO:1901727	biolink:NamedThing	positive regulation of histone deacetylase activity	Any process that activates or increases the frequency, rate or extent of histone deacetylase activity.	got7fsn_ti	activation of histone deacetylase activity|up-regulation of histone deacetylase activity|upregulation of histone deacetylase activity|up regulation of histone deacetylase activity						rl	2013-01-07T09:14:21Z						biological_process											owl:Class	
GO:0005330	biolink:NamedThing	dopamine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in).	got7fsn_ti	dopamine:sodium:chloride symporter activity|dopamine transmembrane transporter activity|sodium/dopamine symporter activity	https://github.com/geneontology/go-ontology/issues/16054									GO:0005329			molecular_function											owl:Class	
GO:0046685	biolink:NamedThing	response to arsenic-containing substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.	got7fsn_ti	arsenate sensitivity/resistance|response to arsenic													biological_process											owl:Class	
GO:0060507	biolink:NamedThing	epidermal growth factor receptor signaling pathway involved in lung development	The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.	got7fsn_ti	epidermal growth factor receptor signalling pathway involved in lung development													biological_process											owl:Class	
GO:0046663	biolink:NamedThing	dorsal closure, leading edge cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure.	got7fsn_ti														biological_process											owl:Class	
GO:1904763	biolink:NamedThing	chaperone-mediated autophagy translocation complex assembly	The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex.	got7fsn_ti	CMA receptor complex assembly|CMA translocation complex formation|chaperone-mediated autophagy receptor complex assembly|chaperone-mediated autophagy translocation complex formation|CMA receptor complex formation|chaperone-mediated autophagy receptor complex formation|CMA translocation complex assembly						pad	2015-10-26T16:34:29Z						biological_process											owl:Class	
GO:0010029	biolink:NamedThing	regulation of seed germination	Any process that modulates the frequency, rate or extent of seed germination.	got7fsn_ti														biological_process											owl:Class	
GO:0015138	biolink:NamedThing	fumarate transmembrane transporter activity	Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.	got7fsn_ti	dicarboxylate (succinate/fumarate/malate) antiporter activity													molecular_function											owl:Class	
GO:0015741	biolink:NamedThing	fumarate transport	The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0060260	biolink:NamedThing	regulation of transcription initiation from RNA polymerase II promoter	Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.	got7fsn_ti														biological_process											owl:Class	
GO:0014837	biolink:NamedThing	myoblast fate determination involved in skeletal muscle regeneration	The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
CHEBI:57305	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015142	biolink:NamedThing	tricarboxylic acid transmembrane transporter activity	Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.	got7fsn_ti	sodium:dicarboxylate/tricarboxylate symporter activity											Reactome:R-HSA-75849|Reactome:R-HSA-372449		molecular_function											owl:Class	
GO:0035674	biolink:NamedThing	tricarboxylic acid transmembrane transport	The process in which a tricarboxylic acid is transported across a membrane.	got7fsn_ti	tricarboxylic acid membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2011-02-08T02:37:31Z						biological_process											owl:Class	
GO:0034632	biolink:NamedThing	retinol transmembrane transporter activity	Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.	got7fsn_ti	vitamin A1 transporter activity|retinol transporter activity											Reactome:R-HSA-1467466|Reactome:R-HSA-2466749|Reactome:R-HSA-2466802		molecular_function											owl:Class	
GO:1902867	biolink:NamedThing	negative regulation of retina development in camera-type eye	Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye.	got7fsn_ti	inhibition of retina development in camera-type eye|down-regulation of retina development in camera-type eye|downregulation of retinal development|down-regulation of retina development in camera-style eye|downregulation of retina development in camera-type eye|inhibition of retinal development|down regulation of retinal development|negative regulation of retinal development|downregulation of retina development in camera-style eye|inhibition of retina development in camera-style eye|down regulation of retina development in camera-type eye|negative regulation of retina development in camera-style eye|down-regulation of retinal development|down regulation of retina development in camera-style eye						mr	2014-04-03T15:24:23Z						biological_process											owl:Class	
GO:0033288	biolink:NamedThing	ATPase-coupled hydroxyectoine transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).	got7fsn_ti	ATP-dependent hydroxyectoine transmembrane transporter activity|hydroxyectoine transmembrane transporter activity|hydroxyectoine-transporting ATPase activity										GO:0033287			molecular_function											owl:Class	
GO:0033308	biolink:NamedThing	hydroxyectoine transport	The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0009504	biolink:NamedThing	cell plate	The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells.	got7fsn_ti												Wikipedia:Cell_plate		cellular_component											owl:Class	
GO:0045471	biolink:NamedThing	response to ethanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.	got7fsn_ti											GO:0017036			biological_process											owl:Class	
GO:0048140	biolink:NamedThing	male germ-line cyst encapsulation	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.	got7fsn_ti														biological_process											owl:Class	
GO:0071655	biolink:NamedThing	regulation of granulocyte colony-stimulating factor production	Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.	got7fsn_ti	regulation of filgrastim production|regulation of CSF3 production|regulation of G-CSF production|regulation of colony stimulating factor 3 (granulocyte) production|regulation of granulocyte colony stimulating factor production|regulation of lenograstim production|regulation of pluripoietin production						mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:1905088	biolink:NamedThing	positive regulation of synaptonemal complex assembly	Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly.	got7fsn_ti	activation of synaptonemal complex assembly|up-regulation of synaptonemal complex assembly|positive regulation of synaptonemal complex formation|upregulation of synaptonemal complex formation|up regulation of synaptonemal complex assembly|upregulation of synaptonemal complex assembly|up-regulation of synaptonemal complex formation|up regulation of synaptonemal complex formation|activation of synaptonemal complex formation						mec	2016-03-30T08:39:03Z						biological_process											owl:Class	
GO:0048938	biolink:NamedThing	lateral line nerve glial cell morphogenesis involved in differentiation	The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.	got7fsn_ti														biological_process											owl:Class	
GO:1904237	biolink:NamedThing	positive regulation of substrate-dependent cell migration, cell attachment to substrate	Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.	got7fsn_ti	up regulation of substrate-dependent cell migration, cell attachment to substrate|positive regulation of substrate-bound cell migration, cell attachment to substrate|up-regulation of substrate-bound cell migration, cell attachment to substrate|activation of substrate-bound cell migration, cell attachment to substrate|up-regulation of substrate-dependent cell migration, cell attachment to substrate|upregulation of substrate-bound cell migration, cell attachment to substrate|activation of substrate-dependent cell migration, cell attachment to substrate|upregulation of substrate-dependent cell migration, cell attachment to substrate|up regulation of substrate-bound cell migration, cell attachment to substrate						pga	2015-05-15T13:30:11Z						biological_process											owl:Class	
GO:0006448	biolink:NamedThing	regulation of translational elongation	Any process that modulates the frequency, rate, extent or accuracy of translational elongation.	got7fsn_ti														biological_process											owl:Class	
GO:0032412	biolink:NamedThing	regulation of ion transmembrane transporter activity	Any process that modulates the activity of an ion transporter.	got7fsn_ti	regulation of ion transporter activity													biological_process											owl:Class	
GO:0062056	biolink:NamedThing	compound eye pigment cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia.	got7fsn_ti							dph	2018-08-01T12:59:42Z						biological_process											owl:Class	
GO:0043323	biolink:NamedThing	positive regulation of natural killer cell degranulation	Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation.	got7fsn_ti	up regulation of natural killer cell degranulation|upregulation of natural killer cell degranulation|positive regulation of NK cell granule exocytosis|positive regulation of natural killer cell granule exocytosis|up-regulation of natural killer cell degranulation|stimulation of natural killer cell degranulation|activation of natural killer cell degranulation|positive regulation of NK cell degranulation													biological_process											owl:Class	
GO:0000127	biolink:NamedThing	transcription factor TFIIIC complex	A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.	got7fsn_ti														cellular_component											owl:Class	
GO:0060673	biolink:NamedThing	cell-cell signaling involved in placenta development	Any process that mediates the transfer of information from one cell to another.	got7fsn_ti	cell-cell signalling involved in placenta development						dph	2009-06-02T12:58:03Z						biological_process											owl:Class	
GO:0032828	biolink:NamedThing	positive regulation of natural killer cell differentiation involved in immune response	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response.	got7fsn_ti	upregulation of natural killer cell differentiation during immune response|stimulation of natural killer cell differentiation during immune response|positive regulation of natural killer cell differentiation during immune response|positive regulation of natural killer cell development involved in immune response|up regulation of natural killer cell differentiation during immune response|positive regulation of NK cell differentiation during immune response|up-regulation of natural killer cell differentiation during immune response|activation of natural killer cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0031282	biolink:NamedThing	regulation of guanylate cyclase activity	Any process that modulates the frequency, rate or extent of guanylate cyclase activity.	got7fsn_ti														biological_process											owl:Class	
GO:0033027	biolink:NamedThing	positive regulation of mast cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process.	got7fsn_ti	upregulation of mast cell apoptosis|up regulation of mast cell apoptosis|stimulation of mast cell apoptosis|positive regulation of mast cell apoptosis|activation of mast cell apoptosis|up-regulation of mast cell apoptosis													biological_process											owl:Class	
GO:0032827	biolink:NamedThing	negative regulation of natural killer cell differentiation involved in immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response.	got7fsn_ti	negative regulation of NK cell differentiation during immune response|down regulation of natural killer cell differentiation during immune response|negative regulation of natural killer cell differentiation during immune response|down-regulation of natural killer cell differentiation during immune response|downregulation of natural killer cell differentiation during immune response|negative regulation of natural killer cell development involved in immune response|inhibition of natural killer cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0061152	biolink:NamedThing	trachea submucosa development	The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.	got7fsn_ti							dph	2010-06-07T09:58:40Z						biological_process											owl:Class	
GO:0015220	biolink:NamedThing	choline transmembrane transporter activity	Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	got7fsn_ti	choline permease activity|amino acid/choline transmembrane transporter activity										GO:0005306	Reactome:R-HSA-6797956|Reactome:R-HSA-429594|Reactome:R-HSA-5658483|Reactome:R-HSA-444433		molecular_function											owl:Class	
PO:0025166	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006839	biolink:NamedThing	mitochondrial transport	Transport of substances into, out of or within a mitochondrion.	got7fsn_ti	mitochondrial alpha-ketoglutarate/malate transport|mitochondrial sodium/calcium ion exchange|mitochondrial aspartate/glutamate transport													biological_process											owl:Class	
GO:0099585	biolink:NamedThing	release of sequestered calcium ion into presynaptic cytosol	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:2000300	biolink:NamedThing	regulation of synaptic vesicle exocytosis	Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.	got7fsn_ti							dph	2011-01-03T08:20:40Z						biological_process											owl:Class	
GO:0008193	biolink:NamedThing	tRNA guanylyltransferase activity	Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs.	got7fsn_ti												EC:2.7.7.79|RHEA:54564		molecular_function											owl:Class	
GO:0099116	biolink:NamedThing	tRNA 5'-end processing	The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.	got7fsn_ti	tRNA 5' processing													biological_process											owl:Class	
GO:0090158	biolink:NamedThing	endoplasmic reticulum membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane.	got7fsn_ti	endoplasmic reticulum membrane organisation						tb	2009-12-08T08:27:17Z						biological_process											owl:Class	
GO:1904303	biolink:NamedThing	positive regulation of maternal process involved in parturition	Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition.	got7fsn_ti	up regulation of maternal process involved in parturition|upregulation of maternal process involved in parturition|up-regulation of maternal process involved in parturition|activation of maternal process involved in parturition						sl	2015-06-09T23:01:45Z						biological_process											owl:Class	
GO:1904748	biolink:NamedThing	regulation of apoptotic process involved in development	Any process that modulates the frequency, rate or extent of apoptotic process involved in development.	got7fsn_ti	regulation of programmed cell death by apoptosis involved in anatomical structure development|regulation of apoptosis involved in anatomical structure development|regulation of apoptotic programmed cell death involved in anatomical structure development|regulation of apoptotic cell death involved in anatomical structure development|regulation of type I programmed cell death involved in anatomical structure development|regulation of apoptotic programmed cell death involved in development of an anatomical structure|regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|regulation of induction of apoptosis by p53 involved in anatomical structure development|regulation of induction of apoptosis involved in development of an anatomical structure|regulation of apoptosis signaling involved in development of an anatomical structure|regulation of type I programmed cell death involved in development of an anatomical structure|regulation of apoptotic program involved in anatomical structure development|regulation of activation of apoptosis involved in development of an anatomical structure|regulation of apoptosis activator activity involved in anatomical structure development|regulation of activation of apoptosis involved in anatomical structure development|regulation of apoptosis signaling involved in anatomical structure development|regulation of apoptotic program involved in development of an anatomical structure|regulation of apoptotic process involved in anatomical structure development|regulation of induction of apoptosis involved in anatomical structure development|regulation of apoptosis involved in development of an anatomical structure|regulation of apoptosis activator activity involved in development of an anatomical structure|regulation of apoptotic process involved in development of an anatomical structure|regulation of commitment to apoptosis involved in anatomical structure development|regulation of commitment to apoptosis involved in development of an anatomical structure|regulation of programmed cell death by apoptosis involved in development of an anatomical structure|regulation of apoptotic cell death involved in development of an anatomical structure|regulation of induction of apoptosis by p53 involved in development of an anatomical structure|regulation of signaling (initiator) caspase activity involved in anatomical structure development				Q10943 in PMID:22801495, inferred from mutant phenotype		es	2015-10-19T15:02:28Z						biological_process											owl:Class	
GO:0002805	biolink:NamedThing	regulation of antimicrobial peptide biosynthetic process	Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0070436	biolink:NamedThing	Grb2-EGFR complex	A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.	got7fsn_ti	Grb2-Egfr complex, EGF stimulated													cellular_component											owl:Class	
GO:0015154	biolink:NamedThing	disaccharide transmembrane transporter activity	Enables the transfer of disaccharide from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015766	biolink:NamedThing	disaccharide transport	The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units.	got7fsn_ti														biological_process											owl:Class	
GO:1903236	biolink:NamedThing	regulation of leukocyte tethering or rolling	Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling.	got7fsn_ti							als	2014-07-31T13:07:48Z						biological_process											owl:Class	
GO:1905916	biolink:NamedThing	negative regulation of cell differentiation involved in phenotypic switching	Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching.	got7fsn_ti	down-regulation of cell differentiation involved in phenotypic switching|inhibition of cell differentiation involved in phenotypic switching|downregulation of cell differentiation involved in phenotypic switching|down regulation of cell differentiation involved in phenotypic switching						rph	2017-02-08T12:23:23Z						biological_process											owl:Class	
GO:0007393	biolink:NamedThing	dorsal closure, leading edge cell fate determination	The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0035029	biolink:NamedThing	dorsal closure, leading edge cell fate commitment	The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis.	got7fsn_ti														biological_process											owl:Class	
GO:0140199	biolink:NamedThing	negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.	got7fsn_ti							pg	2018-02-15T19:31:23Z						biological_process											owl:Class	
GO:0010082	biolink:NamedThing	regulation of root meristem growth	Any process involved in maintaining the size and shape of a root meristem.	got7fsn_ti	regulation of root meristem size													biological_process											owl:Class	
GO:1902120	biolink:NamedThing	negative regulation of meiotic spindle elongation	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation.	got7fsn_ti	inhibition of meiotic spindle elongation|down-regulation of meiotic spindle elongation|negative regulation of spindle elongation during meiosis|downregulation of spindle elongation during meiosis|down-regulation of spindle elongation during meiosis|inhibition of spindle elongation during meiosis|down regulation of spindle elongation during meiosis|down regulation of meiotic spindle elongation|downregulation of meiotic spindle elongation						al	2013-05-15T15:15:53Z						biological_process											owl:Class	
GO:0120231	biolink:NamedThing	DNA recombinase auxiliary factor complex	A protein complex that binds to a recombinase and incrseases its activity.	got7fsn_ti	DNA recombinase activator complex|DNA recombinase accessory factor complex	https://github.com/geneontology/go-ontology/issues/19631					krc	2020-06-18T16:12:52Z						cellular_component											owl:Class	
GO:1902177	biolink:NamedThing	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.	got7fsn_ti	upregulation of intrinsic apoptotic signaling pathway in response to oxidative stress|up regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|activation of intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress						pr	2013-05-29T18:30:10Z						biological_process											owl:Class	
GO:0070126	biolink:NamedThing	mitochondrial translational termination	The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).	got7fsn_ti	mitochondrial translation termination													biological_process											owl:Class	
GO:0007021	biolink:NamedThing	tubulin complex assembly	The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.	got7fsn_ti	tubulin-specific chaperone activity|tubulin assembly|tubulin folding													biological_process											owl:Class	
GO:1901201	biolink:NamedThing	regulation of extracellular matrix assembly	Any process that modulates the frequency, rate or extent of extracellular matrix assembly.	got7fsn_ti							rl	2012-07-27T04:04:00Z						biological_process											owl:Class	
CHEBI:59905	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006297	biolink:NamedThing	nucleotide-excision repair, DNA gap filling	Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.	got7fsn_ti														biological_process											owl:Class	
GO:0038194	biolink:NamedThing	thyroid-stimulating hormone signaling pathway	The series of molecular signals generated as a consequence of thyroid-stimulating hormone (thyrotropin) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	thyrotropin signaling pathway|TSH signaling pathway						bf	2013-10-28T09:03:48Z						biological_process											owl:Class	
GO:1905198	biolink:NamedThing	manchette assembly	The aggregation, arrangement and bonding together of a set of components to form a manchette.	got7fsn_ti	manchette formation						krc	2016-05-12T15:19:08Z						biological_process											owl:Class	
GO:0061221	biolink:NamedThing	mesonephric mesenchyme morphogenesis	The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.	got7fsn_ti							dph	2010-08-19T01:17:38Z						biological_process											owl:Class	
GO:1902959	biolink:NamedThing	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.	got7fsn_ti	regulation of aspartic protease activity involved in amyloid precursor protein catabolism|regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|regulation of aspartate protease activity involved in amyloid precursor protein breakdown|regulation of aspartyl protease activity involved in amyloid precursor protein degradation|regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|regulation of aspartate protease activity involved in amyloid precursor protein catabolism|regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|regulation of aspartic protease activity involved in amyloid precursor protein breakdown|regulation of aspartyl protease activity involved in APP catabolism|regulation of aspartic protease activity involved in APP catabolism|regulation of aspartic endopeptidase activity involved in APP catabolic process|regulation of aspartic-type endopeptidase activity involved in APP catabolism|regulation of aspartic protease activity involved in APP catabolic process|regulation of carboxyl protease activity involved in APP catabolism|regulation of aspartate protease activity involved in APP catabolism|regulation of aspartic endopeptidase activity involved in APP catabolism|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|regulation of aspartate protease activity involved in APP catabolic process|regulation of aspartyl protease activity involved in APP catabolic process|regulation of carboxyl protease activity involved in amyloid precursor protein degradation|regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|regulation of aspartic-type endopeptidase activity involved in APP catabolic process|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|regulation of carboxyl protease activity involved in APP catabolic process|regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|regulation of aspartic protease activity involved in amyloid precursor protein degradation|regulation of aspartate protease activity involved in amyloid precursor protein degradation						sjp	2014-05-06T09:07:04Z						biological_process											owl:Class	
GO:0015056	biolink:NamedThing	corticotrophin-releasing factor receptor activity	Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0071376	biolink:NamedThing	cellular response to corticotropin-releasing hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.	got7fsn_ti	cellular response to corticoliberin stimulus|cellular response to corticotropin-releasing factor stimulus|cellular response to CRH stimulus|cellular response to CRF stimulus						mah	2009-12-11T03:24:56Z						biological_process											owl:Class	
GO:0098877	biolink:NamedThing	neurotransmitter receptor transport to plasma membrane	The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:0005968	biolink:NamedThing	Rab-protein geranylgeranyltransferase complex	An protein-containing complex which catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein. In mammals it is composed of an alpha and a beta subunit, and associates with an accessory protein Rep (Rab escort protein).	got7fsn_ti	RAB-protein geranylgeranyltransferase complex|RabGGTase complex|Rab geranylgeranyltransferase complex|GGTase-II complex													cellular_component											owl:Class	
GO:0090192	biolink:NamedThing	regulation of glomerulus development	Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.	got7fsn_ti							tb	2009-12-18T11:17:13Z						biological_process											owl:Class	
GO:1905903	biolink:NamedThing	negative regulation of mesoderm formation	Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation.	got7fsn_ti	downregulation of mesoderm formation|down-regulation of mesoderm formation|inhibition of mesoderm formation|down regulation of mesoderm formation						rph	2017-02-03T12:28:29Z						biological_process											owl:Class	
CL:0000092	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030700	biolink:NamedThing	glycine reductase complex	Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C.	got7fsn_ti					Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glycine reductase activity ; GO:0030699'.									cellular_component											owl:Class	
GO:0071242	biolink:NamedThing	cellular response to ammonium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.	got7fsn_ti	cellular response to ammonia						mah	2009-12-03T02:39:40Z			GO:1903718			biological_process											owl:Class	
GO:0015436	biolink:NamedThing	ABC-type capsular-polysaccharide transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).	got7fsn_ti	capsular-polysaccharide-transporting ATPase activity|ATPase-coupled capsular-polysaccharide transporter activity|ATP-dependent capsular-polysaccharide transporter activity|capsular-polysaccharide ABC transporter|ATP phosphohydrolase (capsular-polysaccharide-exporting)											MetaCyc:3.6.3.38-RXN|EC:7.6.2.12		molecular_function											owl:Class	
GO:0001583	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of salty taste	The series of events required for a salty taste stimulus to be received and converted to a molecular signal.	got7fsn_ti	sensory detection of chemical stimulus during perception of salty taste|perception of salty taste, detection of chemical stimulus|sensory transduction of salty taste|perception of salty taste, sensory transduction of chemical stimulus|salty taste detection|sensory detection of salty taste|sensory transduction of chemical stimulus during perception of salty taste													biological_process											owl:Class	
GO:0048492	biolink:NamedThing	ribulose bisphosphate carboxylase complex	A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.	got7fsn_ti	RubisCO complex													cellular_component											owl:Class	
GO:0042933	biolink:NamedThing	chrysobactin transmembrane transporter activity	Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other.	got7fsn_ti	chrysobactin transporter activity													molecular_function											owl:Class	
GO:0038029	biolink:NamedThing	epidermal growth factor receptor signaling pathway via MAPK cascade	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on via the MAPKKK cascade.	got7fsn_ti	EGFR signaling pathway via MAPKKK cascade|epidermal growth factor receptor signalling pathway via MAPKKK cascade|epidermal growth factor receptor signaling pathway via MAPKKK cascade|EGFR/MAPK signaling|EGFR signaling via MAPKKK cascade						bf	2011-09-08T10:53:01Z						biological_process											owl:Class	
GO:1904235	biolink:NamedThing	regulation of substrate-dependent cell migration, cell attachment to substrate	Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.	got7fsn_ti	regulation of substrate-bound cell migration, cell attachment to substrate						pga	2015-05-15T13:29:59Z						biological_process											owl:Class	
GO:0098585	biolink:NamedThing	host cell synaptic vesicle membrane	The lipid bilayer surrounding a host synaptic vesicle.	got7fsn_ti							dos	2014-01-24T13:15:14Z						cellular_component											owl:Class	
GO:0098004	biolink:NamedThing	virus tail fiber assembly	The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber.	got7fsn_ti							bm	2012-07-18T16:08:15Z						biological_process											owl:Class	
GO:0098652	biolink:NamedThing	collagen type VII anchoring fibril	An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis.	got7fsn_ti														cellular_component											owl:Class	
GO:0030302	biolink:NamedThing	deoxynucleotide transport	The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0003367	biolink:NamedThing	cell-cell adhesion involved in ameboidal cell migration	The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells.	got7fsn_ti							dph	2009-12-08T05:15:49Z						biological_process											owl:Class	
GO:0003365	biolink:NamedThing	establishment of cell polarity involved in ameboidal cell migration	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.	got7fsn_ti							dph	2009-12-08T04:50:41Z						biological_process											owl:Class	
GO:0033041	biolink:NamedThing	sweet taste receptor activity	Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.	got7fsn_ti														molecular_function											owl:Class	
GO:0001582	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of sweet taste	The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.	got7fsn_ti	perception of sweet taste, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during perception of sweet taste|sweet taste detection|sensory detection of sweet taste|sensory detection of chemical stimulus during perception of sweet taste|perception of sweet taste, detection of chemical stimulus|sensory transduction of sweet taste													biological_process											owl:Class	
GO:0004867	biolink:NamedThing	serine-type endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.	got7fsn_ti	serine protease inhibitor activity|serine proteinase inhibitor activity|serpin activity											Reactome:R-HSA-159001|Reactome:R-HSA-158795|Reactome:R-HSA-158893|Reactome:R-HSA-158800|Reactome:R-HSA-159005		molecular_function											owl:Class	
GO:0033284	biolink:NamedThing	ATPase-coupled carboxylic acid transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).	got7fsn_ti	ATP-dependent carboxylic acid transporter activity|carboxylic acid-transporting ATPase activity													molecular_function											owl:Class	
GO:2001193	biolink:NamedThing	positive regulation of gamma-delta T cell activation involved in immune response	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response.	got7fsn_ti	positive regulation of gamma-delta T lymphocyte activation during immune response|positive regulation of gamma-delta T cell activation during immune response|positive regulation of gamma-delta T-lymphocyte activation during immune response|positive regulation of gamma-delta T-cell activation during immune response						yaf	2011-11-03T04:28:48Z						biological_process											owl:Class	
GO:0021965	biolink:NamedThing	spinal cord ventral commissure morphogenesis	The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0048133	biolink:NamedThing	male germ-line stem cell asymmetric division	The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.	got7fsn_ti	male germ-line stem cell renewal													biological_process											owl:Class	
GO:1901998	biolink:NamedThing	toxin transport	The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							dph	2013-03-19T19:24:55Z						biological_process											owl:Class	
GO:0071395	biolink:NamedThing	cellular response to jasmonic acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.	got7fsn_ti							mah	2009-12-11T04:13:34Z						biological_process											owl:Class	
GO:0038158	biolink:NamedThing	granulocyte colony-stimulating factor signaling pathway	A series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R).	got7fsn_ti	CSF3 signaling pathway|G-CSF receptor signaling pathway|G-CSF signaling pathway|granulocyte colony-stimulating factor signalling pathway|granulocyte colony-stimulating factor receptor signaling pathway						bf	2012-05-14T01:30:28Z						biological_process											owl:Class	
GO:0060700	biolink:NamedThing	regulation of ribonuclease activity	Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.	got7fsn_ti							dph	2009-06-08T02:45:46Z						biological_process											owl:Class	
GO:0098706	biolink:NamedThing	iron ion import across cell outer membrane	The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space.	got7fsn_ti	high-affinity ferric iron transmembrane transport|ferric iron import across cell outer membrane|high affinity ferric iron transport|ferric iron transmembrane transport|ferric ion import into cell|ferric iron import into cell						pr	2012-12-20T08:33:03Z			GO:0015683|GO:0097461			biological_process											owl:Class	
GO:0007040	biolink:NamedThing	lysosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.	got7fsn_ti	lysosome organization and biogenesis|lysosome organisation													biological_process											owl:Class	
GO:0001658	biolink:NamedThing	branching involved in ureteric bud morphogenesis	The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	got7fsn_ti	ureteric bud branching													biological_process											owl:Class	
GO:0007038	biolink:NamedThing	endocytosed protein transport to vacuole	The directed movement of proteins imported into a cell by endocytosis to the vacuole.	got7fsn_ti	delivery of endocytosed proteins to the vacuole				See also the biological process term 'endocytosis ; GO:0006897'.									biological_process											owl:Class	
NCBITaxon:58024	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034228	biolink:NamedThing	ethanolamine transmembrane transporter activity	Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.	got7fsn_ti	2-aminoethanol transmembrane transporter activity|ethanolamine permease activity|monoethanolamine transmembrane transporter activity											RHEA:32747		molecular_function											owl:Class	
GO:0034229	biolink:NamedThing	ethanolamine transport	The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.	got7fsn_ti	2-aminoethanol transport|monoethanolamine transport													biological_process											owl:Class	
GO:0008035	biolink:NamedThing	high-density lipoprotein particle binding	Binding to high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE.	got7fsn_ti	HDL binding													molecular_function											owl:Class	
GO:0071423	biolink:NamedThing	malate transmembrane transport	A process in which a malate ion is transported across a membrane.	got7fsn_ti	malate membrane transport|transmembrane malate transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-12-15T03:31:37Z						biological_process											owl:Class	
GO:0061135	biolink:NamedThing	endopeptidase regulator activity	Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.	got7fsn_ti							dph	2010-05-17T01:19:36Z						molecular_function											owl:Class	
GO:0052548	biolink:NamedThing	regulation of endopeptidase activity	Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.	got7fsn_ti	protease regulator activity													biological_process											owl:Class	
GO:0008199	biolink:NamedThing	ferric iron binding	Binding to a ferric iron ion, Fe(III).	got7fsn_ti														molecular_function											owl:Class	
GO:0099179	biolink:NamedThing	regulation of synaptic membrane adhesion	Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.	got7fsn_ti	regulation of synapse adhesion between pre- and post-synapse													biological_process											owl:Class	
GO:1903740	biolink:NamedThing	positive regulation of phosphatidate phosphatase activity	Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity.	got7fsn_ti	up-regulation of phosphatidic acid phosphatase activity|activation of phosphatic acid phosphatase activity|positive regulation of phosphatidic acid phosphatase activity|up-regulation of 3-sn-phosphatidate phosphohydrolase activity|up regulation of 3-sn-phosphatidate phosphohydrolase activity|up-regulation of phosphatic acid phosphohydrolase activity|up-regulation of phosphatidate phosphohydrolase activity|activation of phosphatidate phosphohydrolase activity|up regulation of phosphatic acid phosphatase activity|activation of phosphatidate phosphatase activity|up-regulation of phosphatic acid phosphatase activity|up regulation of phosphatidate phosphatase activity|upregulation of phosphatidic acid phosphatase activity|positive regulation of phosphatic acid phosphatase activity|positive regulation of 3-sn-phosphatidate phosphohydrolase activity|up regulation of phosphatidic acid phosphatase activity|up regulation of phosphatic acid phosphohydrolase activity|up regulation of phosphatidate phosphohydrolase activity|upregulation of phosphatic acid phosphohydrolase activity|upregulation of acid phosphatidyl phosphatase activity|activation of phosphatic acid phosphohydrolase activity|upregulation of 3-sn-phosphatidate phosphohydrolase activity|positive regulation of phosphatidate phosphohydrolase activity|up-regulation of acid phosphatidyl phosphatase activity|activation of 3-sn-phosphatidate phosphohydrolase activity|positive regulation of phosphatic acid phosphohydrolase activity|positive regulation of acid phosphatidyl phosphatase activity|up regulation of acid phosphatidyl phosphatase activity|activation of acid phosphatidyl phosphatase activity|upregulation of phosphatic acid phosphatase activity|activation of phosphatidic acid phosphatase activity|upregulation of phosphatidate phosphohydrolase activity|upregulation of phosphatidate phosphatase activity|up-regulation of phosphatidate phosphatase activity						tb	2014-12-11T23:37:44Z						biological_process											owl:Class	
GO:0010867	biolink:NamedThing	positive regulation of triglyceride biosynthetic process	Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.	got7fsn_ti	positive regulation of triacylglycerol biosynthetic process													biological_process											owl:Class	
GO:0009999	biolink:NamedThing	negative regulation of auditory receptor cell fate specification	Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell.	got7fsn_ti	suppression of auditory receptor cell fate|downregulation of auditory receptor cell fate specification|down regulation of auditory receptor cell fate specification|suppression of hair cell fate|down-regulation of auditory receptor cell fate specification|inhibition of auditory receptor cell fate specification|negative regulation of auditory hair cell fate specification													biological_process											owl:Class	
GO:0015796	biolink:NamedThing	galactitol transport	The directed movement of galactitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	got7fsn_ti														biological_process											owl:Class	
GO:0060301	biolink:NamedThing	positive regulation of cytokine activity	Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.	got7fsn_ti														biological_process											owl:Class	
GO:0045249	biolink:NamedThing	cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex	A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.	got7fsn_ti					See also the cellular component term 'cytosolic pyruvate dehydrogenase complex ; GO:0045250'.									cellular_component											owl:Class	
GO:0015593	biolink:NamedThing	allose transmembrane transporter activity	Enables the transfer of allose from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	got7fsn_ti														molecular_function											owl:Class	
GO:1903200	biolink:NamedThing	positive regulation of L-dopa decarboxylase activity	Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity.	got7fsn_ti	up-regulation of DDC activity|activation of DOPA decarboxylase activity|up-regulation of DOPA decarboxylase activity|positive regulation of DOPA decarboxylase activity|upregulation of L-dopa decarboxylase activity|activation of DDC activity|up-regulation of L-dopa decarboxylase activity|up regulation of L-dopa decarboxylase activity|activation of L-dopa decarboxylase activity|up regulation of DDC activity|positive regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|up-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|upregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|activation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|upregulation of DOPA decarboxylase activity|upregulation of DDC activity|positive regulation of DDC activity|up regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|up regulation of DOPA decarboxylase activity						bf	2014-07-21T09:32:43Z						biological_process											owl:Class	
GO:1901371	biolink:NamedThing	regulation of leaf morphogenesis	Any process that modulates the frequency, rate or extent of leaf morphogenesis.	got7fsn_ti							tb	2012-09-24T23:07:17Z						biological_process											owl:Class	
GO:0022035	biolink:NamedThing	rhombomere cell migration	The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.	got7fsn_ti														biological_process											owl:Class	
GO:0015173	biolink:NamedThing	aromatic amino acid transmembrane transporter activity	Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring.	got7fsn_ti	aromatic amino acid transporter activity|hydroxy/aromatic amino acid permease activity|valine/tyrosine/tryptophan permease activity													molecular_function											owl:Class	
GO:0015801	biolink:NamedThing	aromatic amino acid transport	The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0043384	biolink:NamedThing	pre-T cell receptor complex	A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins.	got7fsn_ti	pre-T-lymphocyte receptor complex|pre-T-cell receptor complex|pre-TCR complex|pre-T lymphocyte receptor complex													cellular_component											owl:Class	
GO:0033616	biolink:NamedThing	plasma membrane proton-transporting ATP synthase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0048201	biolink:NamedThing	vesicle targeting, plasma membrane to endosome	The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.	got7fsn_ti	plasma membrane to endosome targeting													biological_process											owl:Class	
GO:0045592	biolink:NamedThing	regulation of cumulus cell differentiation	Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation.	got7fsn_ti	regulation of ovarian cumulus cell differentiation													biological_process											owl:Class	
GO:0003922	biolink:NamedThing	GMP synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).	got7fsn_ti	xanthosine 5'-phosphate amidotransferase activity|guanylate synthetase (glutamine-hydrolyzing)|GMP synthetase (glutamine-hydrolysing)|GMP synthetase (glutamine-hydrolyzing) activity|xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)|guanosine monophosphate synthetase (glutamine-hydrolyzing)|guanosine 5'-monophosphate synthetase activity|glutamine amidotransferase activity|GMP synthase (glutamine-hydrolysing)											EC:6.3.5.2|Reactome:R-HSA-73792|MetaCyc:GMP-SYN-GLUT-RXN|RHEA:11680|Wikipedia:GMP_synthase_(glutamine-hydrolysing)		molecular_function											owl:Class	
GO:0061682	biolink:NamedThing	seminal vesicle morphogenesis	The process in which the anatomical structures of a seminal vesicle are generated and organized.	got7fsn_ti							dph	2015-03-04T13:33:49Z						biological_process											owl:Class	
GO:0062235	biolink:NamedThing	axonemal basal plate assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate.	got7fsn_ti	axoneme basal plate assembly|axonemal basal plate formation|basal plate assembly						dph	2020-04-16T12:21:35Z						biological_process											owl:Class	
CL:0000084	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014030	biolink:NamedThing	mesenchymal cell fate commitment	The process in which a cell becomes committed to become a mesenchymal cell.	got7fsn_ti														biological_process											owl:Class	
GO:0097113	biolink:NamedThing	AMPA glutamate receptor clustering	The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.	got7fsn_ti	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|AMPA receptor clustering						pr	2011-07-31T05:25:53Z						biological_process											owl:Class	
GO:0004866	biolink:NamedThing	endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.	got7fsn_ti	endoproteinase inhibitor|proteinase inhibitor|alpha-2 macroglobulin													molecular_function											owl:Class	
GO:0010951	biolink:NamedThing	negative regulation of endopeptidase activity	Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.	got7fsn_ti							tb	2009-04-27T11:47:01Z						biological_process											owl:Class	
GO:0005642	biolink:NamedThing	annulate lamellae	Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER.	got7fsn_ti														cellular_component											owl:Class	
GO:0039638	biolink:NamedThing	lipopolysaccharide-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface.	got7fsn_ti	LPS binding involved in viral attachment to host cell|lipopolysaccharide binding involved in viral attachment to host cell|virion attachment, binding to host lipopolysaccharide						bf	2012-08-17T10:13:06Z						biological_process											owl:Class	
GO:1903724	biolink:NamedThing	positive regulation of centriole elongation	Any process that activates or increases the frequency, rate or extent of centriole elongation.	got7fsn_ti	upregulation of centriole elongation|up-regulation of centriole elongation|up regulation of centriole elongation|activation of centriole elongation						als	2014-12-09T16:36:20Z						biological_process											owl:Class	
GO:0060049	biolink:NamedThing	regulation of protein glycosylation	Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.	got7fsn_ti	regulation of protein amino acid glycosylation													biological_process											owl:Class	
GO:1904382	biolink:NamedThing	mannose trimming involved in glycoprotein ERAD pathway	The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).	got7fsn_ti	glycoprotein mannose trimming involved in gpERAD|protein alpha-1,2-demannosylation involved in gpERAD|glycoprotein mannose trimming involved in glycoprotein ERAD|protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway|glycoprotein mannose trimming involved in ER-associated glycoprotein degradation|protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation|mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process|protein alpha-1,2-demannosylation involved in glycoprotein ERAD|glycoprotein mannose trimming involved in glycoprotein ERAD pathway						bf	2015-06-23T09:46:55Z						biological_process											owl:Class	
GO:1902960	biolink:NamedThing	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.	got7fsn_ti	downregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartic endopeptidase activity involved in APP catabolic process|inhibition of aspartate protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down-regulation of aspartate protease activity involved in amyloid precursor protein breakdown|inhibition of aspartic endopeptidase activity involved in APP catabolism|negative regulation of aspartic protease activity involved in APP catabolism|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein degradation|downregulation of aspartate protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic protease activity involved in APP catabolism|down regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartyl protease activity involved in amyloid precursor protein degradation|down regulation of aspartyl protease activity involved in APP catabolism|negative regulation of carboxyl protease activity involved in APP catabolism|negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of aspartic-type endopeptidase activity involved in APP catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein catabolism|down regulation of carboxyl protease activity involved in APP catabolic process|downregulation of aspartic protease activity involved in APP catabolic process|inhibition of aspartyl protease activity involved in APP catabolism|down regulation of aspartic protease activity involved in APP catabolic process|downregulation of carboxyl protease activity involved in amyloid precursor protein degradation|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|down regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down-regulation of carboxyl protease activity involved in APP catabolic process|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of aspartic protease activity involved in amyloid precursor protein degradation|down-regulation of aspartate protease activity involved in APP catabolism|down-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|downregulation of carboxyl protease activity involved in APP catabolic process|down regulation of aspartate protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartate protease activity involved in amyloid precursor protein catabolic process|inhibition of carboxyl protease activity involved in APP catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein breakdown|down regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartic endopeptidase activity involved in APP catabolism|down regulation of aspartic protease activity involved in amyloid precursor protein degradation|inhibition of carboxyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of aspartyl protease activity involved in APP catabolism|negative regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|downregulation of aspartic protease activity involved in amyloid precursor protein catabolism|downregulation of carboxyl protease activity involved in amyloid precursor protein catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartate protease activity involved in APP catabolism|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|down-regulation of carboxyl protease activity involved in amyloid precursor protein degradation|negative regulation of aspartate protease activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|downregulation of carboxyl protease activity involved in APP catabolism|down-regulation of aspartic protease activity involved in APP catabolism|down regulation of aspartate protease activity involved in amyloid precursor protein catabolism|down regulation of aspartate protease activity involved in amyloid precursor protein degradation|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|down regulation of aspartyl protease activity involved in APP catabolic process|down regulation of aspartyl protease activity involved in amyloid precursor protein degradation|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartic protease activity involved in APP catabolism|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of carboxyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic endopeptidase activity involved in APP catabolic process|negative regulation of aspartic protease activity involved in amyloid precursor protein degradation|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of aspartyl protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|inhibition of carboxyl protease activity involved in amyloid precursor protein breakdown|down regulation of aspartic-type endopeptidase activity involved in APP catabolism|down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartate protease activity involved in amyloid precursor protein degradation|negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic protease activity involved in APP catabolism|inhibition of aspartic-type endopeptidase activity involved in APP catabolic process|negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartate protease activity involved in APP catabolic process|downregulation of aspartic endopeptidase activity involved in APP catabolic process|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of aspartate protease activity involved in amyloid precursor protein degradation|inhibition of carboxyl protease activity involved in APP catabolism|negative regulation of aspartic-type endopeptidase activity involved in APP catabolism|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartyl protease activity involved in APP catabolism|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|negative regulation of aspartate protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartate protease activity involved in amyloid precursor protein catabolism|downregulation of aspartic protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic-type endopeptidase activity involved in APP catabolism|inhibition of aspartate protease activity involved in APP catabolism|downregulation of aspartate protease activity involved in APP catabolism|inhibition of aspartyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|negative regulation of aspartyl protease activity involved in APP catabolic process|down regulation of carboxyl protease activity involved in APP catabolism|downregulation of aspartate protease activity involved in amyloid precursor protein breakdown|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of aspartyl protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartyl protease activity involved in amyloid precursor protein degradation|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartate protease activity involved in APP catabolic process|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of aspartyl protease activity involved in APP catabolic process|down-regulation of aspartic endopeptidase activity involved in APP catabolic process|downregulation of aspartyl protease activity involved in amyloid precursor protein degradation|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of carboxyl protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic-type endopeptidase activity involved in APP catabolic process|negative regulation of aspartate protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|inhibition of aspartic protease activity involved in amyloid precursor protein degradation|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of carboxyl protease activity involved in APP catabolism|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartic endopeptidase activity involved in APP catabolism|negative regulation of aspartic protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic endopeptidase activity involved in APP catabolism|down regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartic-type endopeptidase activity involved in APP catabolic process|negative regulation of carboxyl protease activity involved in amyloid precursor protein degradation|inhibition of aspartic endopeptidase activity involved in APP catabolic process|negative regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|negative regulation of carboxyl protease activity involved in APP catabolic process|inhibition of aspartyl protease activity involved in APP catabolic process|negative regulation of aspartic protease activity involved in amyloid precursor protein catabolism|down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartyl protease activity involved in APP catabolism|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|down regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|inhibition of aspartyl protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartic protease activity involved in amyloid precursor protein degradation|downregulation of aspartyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartate protease activity involved in amyloid precursor protein degradation|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic protease activity involved in amyloid precursor protein breakdown|down regulation of aspartic protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartate protease activity involved in APP catabolism|down-regulation of aspartic protease activity involved in amyloid precursor protein catabolism|down regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartate protease activity involved in APP catabolic process|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic-type endopeptidase activity involved in APP catabolic process|down regulation of aspartic protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic-type endopeptidase activity involved in APP catabolism|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|down regulation of aspartic-type endopeptidase activity involved in APP catabolic process|inhibition of aspartic protease activity involved in APP catabolic process|negative regulation of aspartic protease activity involved in APP catabolic process|down regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|down regulation of carboxyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartyl protease activity involved in APP catabolic process|down regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartate protease activity involved in APP catabolic process|down-regulation of aspartyl protease activity involved in amyloid precursor protein degradation|down-regulation of aspartic protease activity involved in APP catabolic process|down-regulation of aspartic endopeptidase activity involved in APP catabolism						sjp	2014-05-06T09:07:11Z						biological_process											owl:Class	
GO:1903188	biolink:NamedThing	positive regulation of vitellogenesis	Any process that activates or increases the frequency, rate or extent of vitellogenesis.	got7fsn_ti	up-regulation of yolk production|up-regulation of vitellogenesis|upregulation of yolk production|positive regulation of yolk production|up regulation of yolk production|upregulation of vitellogenesis|activation of vitellogenesis|up regulation of vitellogenesis|activation of yolk production						mr	2014-07-14T19:28:12Z						biological_process											owl:Class	
GO:0032433	biolink:NamedThing	filopodium tip	The end of a filopodium distal to the body of the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0015734	biolink:NamedThing	taurine transport	The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1905765	biolink:NamedThing	negative regulation of protection from non-homologous end joining at telomere	Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere.	got7fsn_ti	downregulation of protection from NHEJ-mediated telomere fusion|downregulation of protection from non-homologous end joining at telomere|inhibition of protection from NHEJ-mediated telomere fusion|down regulation of protection from NHEJ-mediated telomere fusion|down-regulation of protection from non-homologous end joining at telomere|down-regulation of protection from NHEJ-mediated telomere fusion|inhibition of protection from non-homologous end joining at telomere|negative regulation of protection from NHEJ-mediated telomere fusion|down regulation of protection from non-homologous end joining at telomere						nc	2016-12-20T11:28:30Z						biological_process											owl:Class	
GO:0016346	biolink:NamedThing	male meiotic chromosome movement towards spindle pole	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis.	got7fsn_ti	male meiotic chromosome movement|chromosome movement towards spindle pole during male meiosis|male meiotic chromosome movement to spindle pole													biological_process											owl:Class	
GO:2000788	biolink:NamedThing	negative regulation of venous endothelial cell fate commitment	Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment.	got7fsn_ti							bf	2011-06-24T01:26:16Z						biological_process											owl:Class	
GO:2000786	biolink:NamedThing	positive regulation of autophagosome assembly	Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.	got7fsn_ti	positive regulation of autophagosome formation|positive regulation of autophagic vacuole assembly|positive regulation of autophagosome biosynthesis|positive regulation of PAS formation|positive regulation of autophagic vacuole formation						rl	2011-06-24T11:19:12Z						biological_process											owl:Class	
GO:0015807	biolink:NamedThing	L-amino acid transport	The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0005754	biolink:NamedThing	mitochondrial proton-transporting ATP synthase, catalytic core	The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.	got7fsn_ti														cellular_component											owl:Class	
GO:1902775	biolink:NamedThing	mitochondrial large ribosomal subunit assembly	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit.	got7fsn_ti	39S ribosomal subunit, mitochondrial assembly|mitochondrial large ribosomal subunit formation|39S ribosomal subunit, mitochondrial formation						mcc	2014-03-18T14:32:19Z						biological_process											owl:Class	
GO:0061668	biolink:NamedThing	mitochondrial ribosome assembly	The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits.	got7fsn_ti							dph	2014-11-07T15:32:20Z						biological_process											owl:Class	
GO:0045859	biolink:NamedThing	regulation of protein kinase activity	Any process that modulates the frequency, rate or extent of protein kinase activity.	got7fsn_ti														biological_process											owl:Class	
GO:0015213	biolink:NamedThing	uridine transmembrane transporter activity	Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.	got7fsn_ti	uracil/uridine permease activity													molecular_function											owl:Class	
GO:0015862	biolink:NamedThing	uridine transport	The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0080122	biolink:NamedThing	AMP transmembrane transporter activity	Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other.	got7fsn_ti	adenosine monophosphate transmembrane transporter activity						dhl	2009-04-28T04:05:39Z						molecular_function											owl:Class	
GO:0080121	biolink:NamedThing	AMP transport	The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	adenosine monophosphate transport						dhl	2009-04-28T04:01:37Z						biological_process											owl:Class	
GO:0021624	biolink:NamedThing	oculomotor nerve structural organization	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	got7fsn_ti	oculomotor nerve structural organisation|CN III structural organization													biological_process											owl:Class	
GO:0110163	biolink:NamedThing	negative regulation of mitotic spindle elongation (spindle phase three)	Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three).	got7fsn_ti							kmv	2019-08-12T15:29:43Z						biological_process											owl:Class	
GO:1903023	biolink:NamedThing	regulation of ascospore-type prospore membrane formation	Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane.	got7fsn_ti	regulation of FSM biosynthesis|regulation of ascospore-type prospore membrane assembly|regulation of forespore membrane formation|regulation of FSM assembly|regulation of forespore membrane biosynthesis|regulation of FSM formation						al	2014-05-15T08:51:51Z						biological_process											owl:Class	
GO:2000321	biolink:NamedThing	positive regulation of T-helper 17 cell differentiation	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation.	got7fsn_ti	positive regulation of T-helper 17 cell development						mah	2011-01-18T01:45:08Z						biological_process											owl:Class	
GO:1902814	biolink:NamedThing	positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.	got7fsn_ti	upregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|up-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|positive regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination						mr	2014-03-26T21:18:56Z						biological_process											owl:Class	
GO:0098854	biolink:NamedThing	podocyte primary projection	A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot.	got7fsn_ti	glomerular visceral epithelial cell primary projection|podocyte major process|primary podocyte process													cellular_component											owl:Class	
GO:0035409	biolink:NamedThing	histone H3-Y41 phosphorylation	The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone.	got7fsn_ti							bf	2010-03-24T10:13:13Z						biological_process											owl:Class	
GO:0015209	biolink:NamedThing	cytosine transmembrane transporter activity	Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015856	biolink:NamedThing	cytosine transport	The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	cytosine transmembrane transport													biological_process											owl:Class	
GO:0042218	biolink:NamedThing	1-aminocyclopropane-1-carboxylate biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.	got7fsn_ti	1-aminocyclopropane-1-carboxylate biosynthesis|1-aminocyclopropane-1-carboxylate formation|1-aminocyclopropane-1-carboxylate anabolism|1-aminocyclopropane-1-carboxylate synthesis													biological_process											owl:Class	
GO:1904429	biolink:NamedThing	regulation of t-circle formation	Any process that modulates the frequency, rate or extent of t-circle formation.	got7fsn_ti	regulation of telomeric circle formation						nc	2015-07-03T15:15:45Z						biological_process											owl:Class	
GO:0098903	biolink:NamedThing	regulation of membrane repolarization during action potential	Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.	got7fsn_ti														biological_process											owl:Class	
GO:0034517	biolink:NamedThing	ribophagy	The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation.	got7fsn_ti														biological_process											owl:Class	
GO:0032790	biolink:NamedThing	ribosome disassembly	The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.	got7fsn_ti	ribosome dissociation factor|ribosome recycling													biological_process											owl:Class	
GO:0099567	biolink:NamedThing	calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration	The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations.	got7fsn_ti	calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels|postsynaptic calcium ion buffering|regulation of postsynaptic cytosolic calcium ion concentration by calcium ion buffering													molecular_function											owl:Class	
GO:0006098	biolink:NamedThing	pentose-phosphate shunt	The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).	got7fsn_ti	pentose phosphate pathway|pentose phosphate shunt|hexose monophosphate pathway|pentose-phosphate pathway											KEGG_PATHWAY:00030|MetaCyc:PENTOSE-P-PWY|Reactome:R-HSA-71336|Wikipedia:Pentose_phosphate_pathway		biological_process											owl:Class	
GO:1905606	biolink:NamedThing	regulation of presynapse assembly	Any process that modulates the frequency, rate or extent of presynapse assembly.	got7fsn_ti	regulation of presynapse biogenesis|regulation of presynaptic terminal assembly						bc	2016-10-27T16:08:13Z						biological_process											owl:Class	
GO:0002362	biolink:NamedThing	CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell.	got7fsn_ti	CD4-positive, CD25-positive, alpha-beta regulatory T-cell lineage commitment|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte lineage commitment|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte lineage commitment													biological_process											owl:Class	
GO:0140195	biolink:NamedThing	positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.	got7fsn_ti							pg	2018-02-15T19:13:11Z						biological_process											owl:Class	
GO:0070289	biolink:NamedThing	extracellular ferritin complex	A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains.	got7fsn_ti	serum ferritin complex													cellular_component											owl:Class	
GO:0042944	biolink:NamedThing	D-alanine transmembrane transporter activity	Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid.	got7fsn_ti	D-alanine transporter activity													molecular_function											owl:Class	
GO:0042941	biolink:NamedThing	D-alanine transport	The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0060392	biolink:NamedThing	negative regulation of SMAD protein signal transduction	Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	got7fsn_ti	negative regulation of SMAD protein import into nucleus|negative regulation of SMAD protein nuclear translocation													biological_process											owl:Class	
GO:0051117	biolink:NamedThing	ATPase binding	Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP.	got7fsn_ti														molecular_function											owl:Class	
GO:0033047	biolink:NamedThing	regulation of mitotic sister chromatid segregation	Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.	got7fsn_ti														biological_process											owl:Class	
GO:1990880	biolink:NamedThing	cellular detoxification of copper ion	Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.	got7fsn_ti							al	2015-10-21T14:34:40Z						biological_process											owl:Class	
GO:0071280	biolink:NamedThing	cellular response to copper ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	got7fsn_ti	cellular response to copper						mah	2009-12-10T03:57:03Z						biological_process											owl:Class	
CL:0000563	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000106	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061222	biolink:NamedThing	mesonephric mesenchymal cell proliferation involved in mesonephros development	The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population.	got7fsn_ti							dph	2010-08-19T01:20:14Z						biological_process											owl:Class	
GO:0021914	biolink:NamedThing	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.	got7fsn_ti	negative regulation of hh signaling pathway involved in ventral spinal cord patterning|downregulation of smoothened signaling pathway in ventral spinal cord patterning|inhibition of smoothened signaling pathway in ventral spinal cord patterning|negative regulation of hedgehog signaling pathway involved in ventral spinal cord patterning|negative regulation of smoothened signalling pathway in ventral spinal cord patterning|down-regulation of smoothened signaling pathway in ventral spinal cord patterning|down regulation of smoothened signaling pathway in ventral spinal cord patterning													biological_process											owl:Class	
GO:1903980	biolink:NamedThing	positive regulation of microglial cell activation	Any process that activates or increases the frequency, rate or extent of microglial cell activation.	got7fsn_ti	activation of microglial cell activation|up regulation of microglial cell activation|upregulation of microglial cell activation|up-regulation of microglial cell activation						nc	2015-03-02T15:17:44Z						biological_process											owl:Class	
GO:0020022	biolink:NamedThing	acidocalcisome	An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.	got7fsn_ti	metachromatic granule|volutin granule|polyphosphate vacuole													cellular_component											owl:Class	
GO:0050652	biolink:NamedThing	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate.	got7fsn_ti	chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthesis|chondroitin sulfate B proteoglycan chain elongation|chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthetic process|dermatan sulfate proteoglycan formation, polysaccharide chain formation|dermatan sulfate proteoglycan synthesis, polysaccharide chain synthesis|dermatan sulfate proteoglycan anabolism, polysaccharide chain anabolism|dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan chain elongation|dermatan sulfate proteoglycan formation, polysaccharide chain biosynthesis													biological_process											owl:Class	
GO:0038197	biolink:NamedThing	type I interferon receptor complex	A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).	got7fsn_ti	interferon-alpha/beta receptor complex						bf	2013-11-27T14:53:50Z						cellular_component											owl:Class	
GO:0051895	biolink:NamedThing	negative regulation of focal adhesion assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.	got7fsn_ti	down regulation of focal adhesion formation|down-regulation of focal adhesion formation|inhibition of focal adhesion formation|downregulation of focal adhesion formation													biological_process											owl:Class	
GO:0019246	biolink:NamedThing	L(+)-lactate biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate.	got7fsn_ti	L(+)-lactate formation from pyruvate|L(+)-lactate synthesis from pyruvate|S-lactate biosynthetic process from pyruvate|L(+)-lactate anabolism from pyruvate											MetaCyc:PWY-5481		biological_process											owl:Class	
GO:0048502	biolink:NamedThing	ABC-type thiamine transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine(out) = ADP + H(+) + phosphate + thiamine(in).	got7fsn_ti	thiamin pyrophosphate transporting ATPase activity|ATPase-coupled thiamine transmembrane transporter activity|ATP-dependent thiamine transmembrane transporter activity|thiamine ABC transporter|thiamine-transporting ATPase activity|thiamin-transporting ATPase activity|thiamin pyrophosphate porter activity|TPP transporting ATPase activity|thiamine pyrophosphate-transporting ATPase activity|thiamin pyrophosphate ABC transporter										GO:0015619	TC:3.A.1.19.1|RHEA:29811|EC:7.6.2.15		molecular_function											owl:Class	
GO:0071934	biolink:NamedThing	thiamine transmembrane transport	The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.	got7fsn_ti	thiamine membrane transport|thiamin transmembrane transport|vitamin B1 transmembrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-09-29T02:59:39Z						biological_process											owl:Class	
GO:0070802	biolink:NamedThing	regulation of metula development	Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.	got7fsn_ti							mah	2009-07-08T04:14:34Z						biological_process											owl:Class	
GO:0150011	biolink:NamedThing	regulation of neuron projection arborization	Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.	got7fsn_ti	regulation of neuron projection branching|regulation of neurite arborization|regulation of neurite branching						bc	2017-12-13T16:32:34Z						biological_process											owl:Class	
UBERON:0006562	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003312	biolink:NamedThing	pancreatic PP cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.	got7fsn_ti	pancreatic polypeptide-producing cell differentiation						dph	2009-10-26T09:32:32Z						biological_process											owl:Class	
GO:0097165	biolink:NamedThing	nuclear stress granule	A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.	got7fsn_ti							pr	2011-09-28T07:49:55Z						cellular_component											owl:Class	
GO:0000809	biolink:NamedThing	cytoplasmic origin of replication recognition complex	A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm.	got7fsn_ti	prokaryotic ORC|cytoplasmic ORC													cellular_component											owl:Class	
GO:2000873	biolink:NamedThing	regulation of histone H4 acetylation involved in response to DNA damage stimulus	Any process that modulates the frequency, rate or extent of histone H4 acetylation involved in response to DNA damage stimulus.	got7fsn_ti	regulation of histone H4 acetylation involved in cellular response to DNA damage stimulus|regulation of histone H4 acetylation involved in cellular DNA damage response|regulation of histone H4 acetylation involved in response to DNA damage|regulation of histone H4 acetylation involved in response to genotoxic stress|regulation of histone H4 acetylation involved in DNA damage response						mah	2011-07-26T10:05:23Z						biological_process											owl:Class	
GO:1905140	biolink:NamedThing	regulation of apical ectodermal ridge formation	Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation.	got7fsn_ti	regulation of crista ectodermalis apicalis formation|regulation of AER formation|regulation of apical epidermal ridge formation						dph	2016-04-13T12:16:40Z						biological_process											owl:Class	
GO:1905904	biolink:NamedThing	positive regulation of mesoderm formation	Any process that activates or increases the frequency, rate or extent of mesoderm formation.	got7fsn_ti	up regulation of mesoderm formation|upregulation of mesoderm formation|up-regulation of mesoderm formation|activation of mesoderm formation						rph	2017-02-03T12:28:38Z						biological_process											owl:Class	
GO:0001178	biolink:NamedThing	regulation of transcriptional start site selection at RNA polymerase II promoter	Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	got7fsn_ti	regulation of transcriptional start site selection at RNA polymerase II promoter|regulation of transcription start site selection at RNA polymerase II promoter						krc	2011-06-20T02:06:00Z						biological_process											owl:Class	
GO:1904943	biolink:NamedThing	negative regulation of cardiac ventricle formation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation.	got7fsn_ti	down regulation of cardiac ventricle formation|down-regulation of cardiac ventricle formation|inhibition of cardiac ventricle formation|downregulation of cardiac ventricle formation						bc	2016-02-02T16:37:24Z						biological_process											owl:Class	
GO:1904514	biolink:NamedThing	positive regulation of initiation of premeiotic DNA replication	Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication.	got7fsn_ti	positive regulation of initiation of meiotic DNA synthesis|up regulation of initiation of premeiotic DNA synthesis|up regulation of meiotic DNA replication initiation|upregulation of initiation of meiotic DNA synthesis|upregulation of initiation of premeiotic DNA synthesis|up-regulation of premeiotic DNA replication initiation|up-regulation of initiation of premeiotic DNA replication|positive regulation of premeiotic DNA replication initiation|up regulation of initiation of meiotic DNA synthesis|upregulation of premeiotic DNA replication initiation|activation of initiation of premeiotic DNA synthesis|activation of initiation of premeiotic DNA replication|upregulation of initiation of premeiotic DNA replication|up-regulation of meiotic DNA replication initiation|positive regulation of meiotic DNA replication initiation|up regulation of initiation of premeiotic DNA replication|activation of initiation of meiotic DNA synthesis|positive regulation of initiation of premeiotic DNA synthesis|up regulation of premeiotic DNA replication initiation|up-regulation of initiation of meiotic DNA synthesis|activation of premeiotic DNA replication initiation|activation of meiotic DNA replication initiation|up-regulation of initiation of premeiotic DNA synthesis|upregulation of meiotic DNA replication initiation						mah	2015-07-28T12:59:29Z						biological_process											owl:Class	
GO:0075308	biolink:NamedThing	negative regulation of conidium formation	Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	got7fsn_ti														biological_process											owl:Class	
GO:0001646	biolink:NamedThing	cAMP receptor activity	Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	got7fsn_ti	class E G protein coupled receptor|cyclic AMP receptor activity|class E GPCR|3',5'-cAMP receptor activity|3',5' cAMP receptor activity|class E G-protein coupled receptor|adenosine 3',5'-cyclophosphate receptor activity										GO:0001644			molecular_function											owl:Class	
GO:0005964	biolink:NamedThing	phosphorylase kinase complex	An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a.	got7fsn_ti														cellular_component											owl:Class	
GO:0070610	biolink:NamedThing	regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.	got7fsn_ti	regulation of fungal-type cell wall 1,3-alpha-glucan formation|regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process|regulation of fungal-type cell wall alpha-1,3-glucan biosynthetic process|regulation of fungal-type cell wall 1,3-alpha-glucan biosynthesis|regulation of fungal-type cell wall alpha-1,3-glucan biosynthesis|regulation of fungal-type cell wall alpha-1,3-glucan formation|regulation of fungal-type cell wall 1,3-alpha-glucan synthesis|regulation of fungal-type cell wall 1,3-alpha-glucan anabolism|regulation of fungal-type cell wall alpha-1,3-glucan synthesis|regulation of fungal-type cell wall alpha-1,3-glucan anabolism						mah	2009-04-29T01:32:19Z						biological_process											owl:Class	
GO:0071917	biolink:NamedThing	triose-phosphate transmembrane transporter activity	Enables the transfer of a triose phosphate from one side of a membrane to the other.	got7fsn_ti							mah	2010-09-24T10:35:26Z						molecular_function											owl:Class	
GO:0035436	biolink:NamedThing	triose phosphate transmembrane transport	The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester.	got7fsn_ti	triose phosphate membrane transport|triose phosphate transmembrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T02:54:07Z						biological_process											owl:Class	
GO:0015767	biolink:NamedThing	lactose transport	The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.	got7fsn_ti														biological_process											owl:Class	
GO:0060331	biolink:NamedThing	negative regulation of response to interferon-gamma	Any process that decreases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.	got7fsn_ti	negative regulation of response to immune interferon|negative regulation of response to type II interferon|negative regulation of response to gamma-interferon|negative regulation of response to type II IFN													biological_process											owl:Class	
GO:0036054	biolink:NamedThing	protein-malonyllysine demalonylase activity	Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide.	got7fsn_ti	protein lysine demalonylation activity|peptidyl-malonyllysine demalonylase activity|protein malonyl lysine demalonylation activity						bf	2011-12-12T01:29:21Z						molecular_function											owl:Class	
GO:0045214	biolink:NamedThing	sarcomere organization	The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	got7fsn_ti	sarcomere organisation|sarcomere alignment										GO:0006938			biological_process											owl:Class	
GO:0032278	biolink:NamedThing	positive regulation of gonadotropin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.	got7fsn_ti	positive regulation of gonadotrophin secretion|upregulation of gonadotropin secretion|up-regulation of gonadotropin secretion|activation of gonadotropin secretion|stimulation of gonadotropin secretion|up regulation of gonadotropin secretion													biological_process											owl:Class	
GO:0021887	biolink:NamedThing	hypothalamus gonadotrophin-releasing hormone neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone.	got7fsn_ti	hypothalamus gonadotropin-releasing hormone neuron fate commitment													biological_process											owl:Class	
GO:1904031	biolink:NamedThing	positive regulation of cyclin-dependent protein kinase activity	Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity.	got7fsn_ti	activation of cyclin-dependent protein kinase activity|up-regulation of cyclin-dependent protein kinase activity|upregulation of cyclin-dependent protein kinase activity|up regulation of cyclin-dependent protein kinase activity						als	2015-03-13T15:43:50Z						biological_process											owl:Class	
GO:0030177	biolink:NamedThing	positive regulation of Wnt signaling pathway	Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.	got7fsn_ti	up regulation of frizzled signaling pathway|positive regulation of Wnt-activated signaling pathway|positive regulation of Wnt receptor signaling pathway|activation of Wnt receptor signaling pathway|up-regulation of Wnt receptor signaling pathway|positive regulation of Wnt receptor signalling pathway|upregulation of frizzled signaling pathway|stimulation of frizzled signaling pathway|activation of frizzled signaling pathway|up regulation of Wnt receptor signaling pathway|up-regulation of frizzled signaling pathway|positive regulation of frizzled signalling pathway|positive regulation of frizzled signaling pathway|upregulation of Wnt receptor signaling pathway|stimulation of Wnt receptor signaling pathway										GO:0045811			biological_process											owl:Class	
GO:0015414	biolink:NamedThing	ABC-type nitrate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in).	got7fsn_ti	nitrate transporting ATPase activity|ATPase-coupled nitrate transmembrane transporter activity|nitrate transmembrane-transporting ATPase activity|nitrate ABC transporter|nitrate-transporting ATPase activity											RHEA:13181|MetaCyc:3.6.3.26-RXN|EC:7.3.2.4		molecular_function											owl:Class	
GO:0003381	biolink:NamedThing	epithelial cell morphogenesis involved in gastrulation	The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.	got7fsn_ti							dph	2009-12-09T07:18:53Z						biological_process											owl:Class	
GO:2000102	biolink:NamedThing	negative regulation of mammary stem cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation.	got7fsn_ti							dph	2010-09-14T06:10:34Z						biological_process											owl:Class	
GO:0015158	biolink:NamedThing	raffinose transmembrane transporter activity	Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.	got7fsn_ti	raffinose permease													molecular_function											owl:Class	
GO:0015773	biolink:NamedThing	raffinose transport	The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.	got7fsn_ti														biological_process											owl:Class	
GO:0003326	biolink:NamedThing	pancreatic A cell fate commitment	The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.	got7fsn_ti							dph	2009-11-02T08:29:00Z						biological_process											owl:Class	
GO:0045625	biolink:NamedThing	regulation of T-helper 1 cell differentiation	Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.	got7fsn_ti	regulation of T-helper 1 cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0031928	biolink:NamedThing	pyridoxine transmembrane transporter activity	Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti	pyridoxine transporter activity													molecular_function											owl:Class	
GO:1903092	biolink:NamedThing	pyridoxine transmembrane transport	The process in which pyridoxine is transported across a membrane.	got7fsn_ti							al	2014-06-03T10:41:26Z						biological_process											owl:Class	
GO:0014833	biolink:NamedThing	skeletal muscle satellite stem cell asymmetric division	The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool.	got7fsn_ti	satellite cell asymmetric division													biological_process											owl:Class	
CL:0000362	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048083	biolink:NamedThing	negative regulation of adult chitin-containing cuticle pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.	got7fsn_ti	down-regulation of adult chitin-containing cuticle pigmentation|inhibition of adult chitin-containing cuticle pigmentation|downregulation of adult chitin-containing cuticle pigmentation|down regulation of adult chitin-containing cuticle pigmentation													biological_process											owl:Class	
GO:0007318	biolink:NamedThing	pole plasm protein localization	Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	got7fsn_ti	pole plasm protein localisation|establishment and maintenance of pole plasm protein localization|oocyte pole plasm protein localization										GO:0048115			biological_process											owl:Class	
GO:0035744	biolink:NamedThing	T-helper 1 cell cytokine production	Any process that contributes to cytokine production by a T-helper 1 cell.	got7fsn_ti	Th1 cell cytokine production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-03-17T02:22:54Z						biological_process											owl:Class	
GO:0039631	biolink:NamedThing	DNA translocase activity involved in viral DNA genome packaging	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule, that contributes to the packing of viral DNA into a capsid.	got7fsn_ti	viral DNA packaging motor activity|viral DNA packaging activity						bf	2012-08-07T11:17:07Z						molecular_function											owl:Class	
GO:0015212	biolink:NamedThing	cytidine transmembrane transporter activity	Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015861	biolink:NamedThing	cytidine transport	The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0032127	biolink:NamedThing	dense core granule membrane	The lipid bilayer surrounding a dense core granule.	got7fsn_ti	dense core vesicle membrane													cellular_component											owl:Class	
GO:0034506	biolink:NamedThing	chromosome, centromeric core domain	The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.	got7fsn_ti	chromosome, centromeric core region|chromosome, centric core region													cellular_component											owl:Class	
GO:0000319	biolink:NamedThing	sulfite transmembrane transporter activity	Enables the transfer of sulfite ions from one side of a membrane to the other.	got7fsn_ti	sulphite transporter activity													molecular_function											owl:Class	
GO:0000316	biolink:NamedThing	sulfite transport	The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	sulphite transport													biological_process											owl:Class	
GO:0060924	biolink:NamedThing	atrial cardiac muscle cell fate commitment	The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	got7fsn_ti	atrial cardiomyocyte cell fate commitment|atrial heart muscle cell fate commitment						dph	2009-09-29T11:46:10Z						biological_process											owl:Class	
GO:1903914	biolink:NamedThing	negative regulation of fusion of virus membrane with host plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane.	got7fsn_ti	down-regulation of fusion of virus membrane with host plasma membrane|inhibition of viral envelope fusion with host cell membrane|negative regulation of viral-cell fusion molecule activity|down-regulation of viral envelope fusion with host cell membrane|down-regulation of viral-cell fusion molecule activity|downregulation of viral entry into host cell via membrane fusion with the plasma membrane|inhibition of fusion of virus membrane with host plasma membrane|inhibition of viral-cell fusion molecule activity|inhibition of viral entry into host cell via membrane fusion with the plasma membrane|negative regulation of viral penetration via membrane fusion|negative regulation of viral envelope fusion with host membrane|down regulation of viral envelope fusion with host cell membrane|down regulation of viral penetration via membrane fusion|down-regulation of viral entry into host cell via membrane fusion with the plasma membrane|inhibition of viral envelope fusion with host plasma membrane|downregulation of viral envelope fusion with host cell membrane|downregulation of viral envelope fusion with host membrane|negative regulation of viral entry into host cell via membrane fusion with the plasma membrane|down regulation of viral entry into host cell via membrane fusion with the plasma membrane|down-regulation of viral envelope fusion with host membrane|downregulation of viral penetration via membrane fusion|negative regulation of viral envelope fusion with host cell membrane|negative regulation of viral envelope fusion with host plasma membrane|down regulation of viral envelope fusion with host plasma membrane|down-regulation of viral penetration via membrane fusion|down-regulation of viral envelope fusion with host plasma membrane|inhibition of viral penetration via membrane fusion|inhibition of viral envelope fusion with host membrane|downregulation of viral-cell fusion molecule activity|downregulation of viral envelope fusion with host plasma membrane|down regulation of fusion of virus membrane with host plasma membrane|down regulation of viral-cell fusion molecule activity|downregulation of fusion of virus membrane with host plasma membrane|down regulation of viral envelope fusion with host membrane						als	2015-02-09T11:13:32Z						biological_process											owl:Class	
GO:0000957	biolink:NamedThing	mitochondrial RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.	got7fsn_ti														biological_process											owl:Class	
GO:1905208	biolink:NamedThing	negative regulation of cardiocyte differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation.	got7fsn_ti	down regulation of heart cell differentiation|downregulation of cardiac cell differentiation|down regulation of cardiocyte differentiation|down regulation of cardiac cell differentiation|downregulation of cardiocyte differentiation|down-regulation of heart cell differentiation|negative regulation of cardiac cell differentiation|inhibition of cardiac cell differentiation|inhibition of cardiocyte differentiation|down-regulation of cardiac cell differentiation|inhibition of heart cell differentiation|downregulation of heart cell differentiation|negative regulation of heart cell differentiation|down-regulation of cardiocyte differentiation						bc	2016-06-02T07:20:09Z						biological_process											owl:Class	
GO:0098897	biolink:NamedThing	spine apparatus membrane	The lipid bilayer surrounding the spine apparatus.	got7fsn_ti														cellular_component											owl:Class	
GO:1905753	biolink:NamedThing	positive regulation of argininosuccinate synthase activity	Any process that activates or increases the frequency, rate or extent of argininosuccinate synthase activity.	got7fsn_ti	activation of L-citrulline:L-aspartate ligase (AMP-forming)|positive regulation of arginine succinate synthetase activity|activation of arginosuccinate synthetase activity|positive regulation of argininosuccinate synthetase activity|upregulation of argininosuccinic acid synthetase activity|upregulation of citrulline--aspartate ligase activity|upregulation of arginine succinate synthetase activity|up-regulation of citrulline--aspartate ligase activity|upregulation of argininosuccinate synthase activity|activation of argininosuccinate synthase activity|up regulation of argininosuccinate synthetase activity|activation of argininosuccinate synthetase activity|activation of arginine succinate synthetase activity|positive regulation of citrulline--aspartate ligase activity|positive regulation of L-citrulline:L-aspartate ligase (AMP-forming)|up regulation of citrulline--aspartate ligase activity|up-regulation of L-citrulline:L-aspartate ligase (AMP-forming)|up-regulation of argininosuccinic acid synthetase activity|positive regulation of arginosuccinate synthetase activity|up-regulation of argininosuccinate synthetase activity|upregulation of arginosuccinate synthetase activity|activation of argininosuccinic acid synthetase activity|upregulation of L-citrulline:L-aspartate ligase (AMP-forming)|up regulation of arginine succinate synthetase activity|up regulation of argininosuccinic acid synthetase activity|up regulation of arginosuccinate synthetase activity|up-regulation of arginine succinate synthetase activity|up regulation of L-citrulline:L-aspartate ligase (AMP-forming)|up-regulation of arginosuccinate synthetase activity|up regulation of argininosuccinate synthase activity|activation of citrulline--aspartate ligase activity|up-regulation of argininosuccinate synthase activity|upregulation of argininosuccinate synthetase activity|positive regulation of argininosuccinic acid synthetase activity						dos	2016-12-12T11:44:09Z						biological_process											owl:Class	
GO:0015439	biolink:NamedThing	ABC-type heme transporter activity	Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).	got7fsn_ti	haem-transporting ATPase activity|protoheme IX ABC transporter activity|ATP-dependent heme transmembrane transporter activity|ATPase-coupled heme transporter activity|ATPase-coupled heme transmembrane transporter activity|heme ABC transporter|heme-transporting ATPase activity										GO:0103115	MetaCyc:3.6.3.41-RXN|MetaCyc:TRANS-RXN0-162|Reactome:R-HSA-5683355|Reactome:R-HSA-382560|EC:7.6.2.5|RHEA:19261|Reactome:R-HSA-1369065|Reactome:R-HSA-917979		molecular_function											owl:Class	
GO:0035351	biolink:NamedThing	heme transmembrane transport	The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	heme membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:45:46Z						biological_process											owl:Class	
OBO:OBA_0000143	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0106163	biolink:NamedThing	regulation of exonucleolytic catabolism of deadenylated mRNA	Any process that modulates the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.	got7fsn_ti							hjd	2019-01-15T15:33:08Z						biological_process											owl:Class	
GO:0043321	biolink:NamedThing	regulation of natural killer cell degranulation	Any process that modulates the frequency, rate, or extent of natural killer cell degranulation.	got7fsn_ti	regulation of natural killer cell granule exocytosis|regulation of NK cell degranulation|regulation of NK cell granule exocytosis													biological_process											owl:Class	
GO:0042887	biolink:NamedThing	amide transmembrane transporter activity	Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other.	got7fsn_ti	amine/amide/polyamine channel activity													molecular_function											owl:Class	
GO:1903050	biolink:NamedThing	regulation of proteolysis involved in cellular protein catabolic process	Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.	got7fsn_ti	regulation of peptidolysis during cellular protein catabolism|regulation of proteolysis during cellular protein catabolic process|regulation of peptidolysis during cellular protein catabolic process|regulation of proteolysis during cellular protein catabolism|regulation of peptidolysis involved in cellular protein catabolism|regulation of peptidolysis involved in cellular protein catabolic process				overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)		rl	2014-05-22T18:00:45Z						biological_process											owl:Class	
GO:0051797	biolink:NamedThing	regulation of hair follicle development	Any process that modulates the frequency, rate or extent of hair follicle development.	got7fsn_ti														biological_process											owl:Class	
UBERON:0001016	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000480	biolink:NamedThing	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable.	got7fsn_ti	endonucleolytic cleavage at A-prime|endonucleolytic cleavage at A0													biological_process											owl:Class	
GO:0033008	biolink:NamedThing	positive regulation of mast cell activation involved in immune response	Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response.	got7fsn_ti	positive regulation of mast cell activation during immune response													biological_process											owl:Class	
GO:0006182	biolink:NamedThing	cGMP biosynthetic process	The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate.	got7fsn_ti	cGMP formation|cGMP biosynthesis|cGMP synthesis|cGMP anabolism													biological_process											owl:Class	
GO:0099572	biolink:NamedThing	postsynaptic specialization	A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.	got7fsn_ti														cellular_component											owl:Class	
GO:0005260	biolink:NamedThing	intracellularly ATP-gated chloride channel activity	Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.	got7fsn_ti	ATP-binding and phosphorylation-dependent chloride channel activity|ATP phosphohydrolase (channel-conductance-controlling)|cystic-fibrosis membrane-conductance-regulating protein activity|channel-conductance-controlling ATPase activity|cystic fibrosis transmembrane conductance regulator	https://github.com/geneontology/go-ontology/issues/14402									GO:0005224	MetaCyc:3.6.3.49-RXN|EC:5.6.1.6		molecular_function											owl:Class	
GO:0042664	biolink:NamedThing	negative regulation of endodermal cell fate specification	Any process that restricts, stops or prevents a cell from specifying into an endoderm cell.	got7fsn_ti	inhibition of endodermal cell fate specification|down regulation of endodermal cell fate specification|down-regulation of endodermal cell fate specification|suppression of endodermal cell fate|suppression of endoderm cell fate|downregulation of endodermal cell fate specification|negative regulation of endoderm cell fate specification													biological_process											owl:Class	
GO:1904595	biolink:NamedThing	positive regulation of termination of RNA polymerase II transcription	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.	got7fsn_ti	upregulation of RNA 3'-end formation by RNA polymerase II|positive regulation of RNA 3'-end formation by RNA polymerase II|up regulation of transcription termination from Pol II promoter|positive regulation of transcription termination from Pol II promoter|activation of RNA polymerase II transcription termination|up regulation of transcription termination from RNA polymerase II promoter|up regulation of termination of RNA polymerase II transcription|upregulation of termination of RNA polymerase II transcription|positive regulation of RNA polymerase II transcription termination|up regulation of RNA polymerase II transcription termination|up-regulation of transcription termination from Pol II promoter|up-regulation of RNA polymerase II transcription termination factor activity|upregulation of RNA polymerase II transcription termination|activation of RNA 3'-end formation by RNA polymerase II|upregulation of transcription termination from Pol II promoter|activation of termination of RNA polymerase II transcription|up regulation of RNA 3'-end formation by RNA polymerase II|up-regulation of termination of RNA polymerase II transcription|up-regulation of RNA polymerase II transcription termination|activation of transcription termination from Pol II promoter|upregulation of RNA polymerase II transcription termination factor activity|positive regulation of transcription termination from RNA polymerase II promoter|up-regulation of RNA 3'-end formation by RNA polymerase II|positive regulation of RNA polymerase II transcription termination factor activity|upregulation of transcription termination from RNA polymerase II promoter|activation of RNA polymerase II transcription termination factor activity|up regulation of RNA polymerase II transcription termination factor activity|activation of transcription termination from RNA polymerase II promoter|up-regulation of transcription termination from RNA polymerase II promoter						al	2015-08-25T08:56:14Z						biological_process											owl:Class	
GO:0050542	biolink:NamedThing	icosanoid binding	Binding to icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids.	got7fsn_ti	eicosanoid binding													molecular_function											owl:Class	
GO:0036224	biolink:NamedThing	pairing center	A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment.	got7fsn_ti	homolog recognition region						bf	2012-05-09T02:28:53Z						cellular_component											owl:Class	
GO:0060463	biolink:NamedThing	lung lobe morphogenesis	The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.	got7fsn_ti														biological_process											owl:Class	
GO:1903048	biolink:NamedThing	regulation of acetylcholine-gated cation channel activity	Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity.	got7fsn_ti							bf	2014-05-22T14:46:53Z						biological_process											owl:Class	
GO:0043304	biolink:NamedThing	regulation of mast cell degranulation	Any process that modulates the frequency, rate, or extent of mast cell degranulation.	got7fsn_ti	regulation of mast cell granule exocytosis													biological_process											owl:Class	
GO:0060137	biolink:NamedThing	maternal process involved in parturition	A reproductive process occurring in the mother that results in birth.	got7fsn_ti														biological_process											owl:Class	
GO:0015159	biolink:NamedThing	polysaccharide transmembrane transporter activity	Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	got7fsn_ti														molecular_function											owl:Class	
GO:0015141	biolink:NamedThing	succinate transmembrane transporter activity	Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other.	got7fsn_ti	dicarboxylate (succinate/fumarate/malate) antiporter activity													molecular_function											owl:Class	
GO:0071422	biolink:NamedThing	succinate transmembrane transport	The process in which succinate is transported across a membrane.	got7fsn_ti	succinate membrane transport|transmembrane succinate transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-12-15T03:29:44Z						biological_process											owl:Class	
GO:0015087	biolink:NamedThing	cobalt ion transmembrane transporter activity	Enables the transfer of cobalt (Co) ions from one side of a membrane to the other.	got7fsn_ti	cobalt, zinc uptake permease activity|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity											RHEA:28578		molecular_function											owl:Class	
GO:2000392	biolink:NamedThing	regulation of lamellipodium morphogenesis	Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis.	got7fsn_ti	regulation of lamellipodium organization						mah	2011-02-22T11:18:58Z						biological_process											owl:Class	
GO:0031134	biolink:NamedThing	sister chromatid biorientation	The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.	got7fsn_ti	sister kinetochore biorientation|chromosome biorientation													biological_process											owl:Class	
GO:1902957	biolink:NamedThing	negative regulation of mitochondrial electron transport, NADH to ubiquinone	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.	got7fsn_ti	down-regulation of mitochondrial electron transport, NADH to ubiquinone|negative regulation of oxidative phosphorylation, NADH to ubiquinone|inhibition of oxidative phosphorylation, NADH to ubiquinone|inhibition of complex I (NADH to ubiquinone)|inhibition of mitochondrial electron transport, NADH to ubiquinone|down regulation of mitochondrial electron transport, NADH to ubiquinone|downregulation of complex I (NADH to ubiquinone)|down-regulation of oxidative phosphorylation, NADH to ubiquinone|downregulation of oxidative phosphorylation, NADH to ubiquinone|down regulation of oxidative phosphorylation, NADH to ubiquinone|negative regulation of complex I (NADH to ubiquinone)|downregulation of mitochondrial electron transport, NADH to ubiquinone|down-regulation of complex I (NADH to ubiquinone)|down regulation of complex I (NADH to ubiquinone)						dph	2014-05-02T15:30:18Z						biological_process											owl:Class	
GO:0033042	biolink:NamedThing	umami taste receptor activity	Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates.	got7fsn_ti														molecular_function											owl:Class	
GO:0046535	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of umami taste	The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates.	got7fsn_ti	umami taste detection|perception of umami taste, detection of chemical stimulus|sensory transduction of chemical stimulus during perception of umami taste|sensory detection of umami taste|sensory transduction of umami taste|sensory detection of chemical stimulus during perception of umami taste|perception of umami taste, sensory transduction of chemical stimulus													biological_process											owl:Class	
GO:0002899	biolink:NamedThing	negative regulation of central B cell deletion	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.	got7fsn_ti	down-regulation of central B cell deletion|inhibition of central B cell deletion|downregulation of central B cell deletion|down regulation of central B cell deletion													biological_process											owl:Class	
GO:0035745	biolink:NamedThing	T-helper 2 cell cytokine production	Any process that contributes to cytokine production by a T-helper 2 cell.	got7fsn_ti	Th2 cell cytokine production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-03-17T02:23:32Z						biological_process											owl:Class	
GO:0048902	biolink:NamedThing	anterior lateral line neuromast deposition	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.	got7fsn_ti														biological_process											owl:Class	
GO:0072206	biolink:NamedThing	metanephric juxtaglomerular apparatus development	The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.	got7fsn_ti							mah	2010-03-18T11:17:47Z						biological_process											owl:Class	
GO:2000004	biolink:NamedThing	regulation of metanephric S-shaped body morphogenesis	Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis.	got7fsn_ti							jl	2010-07-30T02:14:33Z						biological_process											owl:Class	
GO:2000651	biolink:NamedThing	positive regulation of sodium ion transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.	got7fsn_ti	positive regulation of sodium transporter activity						yaf	2011-04-28T08:43:00Z						biological_process											owl:Class	
GO:0071085	biolink:NamedThing	alphaIIb-beta3 integrin-CD9 complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.	got7fsn_ti	ITGA2b-ITGB3-CD9 complex						mah	2009-11-06T04:44:52Z						cellular_component											owl:Class	
GO:0015749	biolink:NamedThing	monosaccharide transmembrane transport	The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.	got7fsn_ti	monosaccharide transport						vw	2017-02-19T10:41:27Z			GO:1905950			biological_process											owl:Class	
GO:0002834	biolink:NamedThing	regulation of response to tumor cell	Any process that modulates the frequency, rate, or extent of a response to tumor cell.	got7fsn_ti	regulation of response to tumour cell													biological_process											owl:Class	
GO:0030173	biolink:NamedThing	integral component of Golgi membrane	The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	Golgi integral membrane protein|integral to Golgi membrane													cellular_component											owl:Class	
GO:0015229	biolink:NamedThing	L-ascorbic acid transmembrane transporter activity	Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.	got7fsn_ti	L-ascorbate transporter activity|vitamin C transporter activity											Reactome:R-HSA-198870		molecular_function											owl:Class	
GO:1904254	biolink:NamedThing	regulation of iron ion transmembrane transporter activity	Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity.	got7fsn_ti	regulation of iron cation channel activity|regulation of iron-specific channel activity|regulation of iron channel activity						kom	2015-05-20T14:05:00Z						biological_process											owl:Class	
CL:0002063	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060743	biolink:NamedThing	epithelial cell maturation involved in prostate gland development	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.	got7fsn_ti	prostate gland epithelial cell development						dph	2009-06-16T09:34:42Z						biological_process											owl:Class	
GO:0048814	biolink:NamedThing	regulation of dendrite morphogenesis	Any process that modulates the frequency, rate or extent of dendrite morphogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:0043305	biolink:NamedThing	negative regulation of mast cell degranulation	Any process that stops, prevents, or reduces the rate of mast cell degranulation.	got7fsn_ti	down regulation of mast cell degranulation|inhibition of mast cell degranulation|down-regulation of mast cell degranulation|downregulation of mast cell degranulation|negative regulation of mast cell granule exocytosis													biological_process											owl:Class	
GO:0019082	biolink:NamedThing	viral protein processing	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.	got7fsn_ti														biological_process											owl:Class	
GO:1901217	biolink:NamedThing	regulation of holin activity	Any process that modulates the frequency, rate or extent of holin activity.	got7fsn_ti							bf	2012-08-06T10:47:38Z						biological_process											owl:Class	
GO:2000227	biolink:NamedThing	negative regulation of pancreatic A cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation.	got7fsn_ti	negative regulation of pancreatic alpha cell differentiation						mah	2010-11-09T03:43:40Z						biological_process											owl:Class	
GO:0071108	biolink:NamedThing	protein K48-linked deubiquitination	A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.	got7fsn_ti							mah	2009-11-12T01:34:01Z						biological_process											owl:Class	
GO:0015228	biolink:NamedThing	coenzyme A transmembrane transporter activity	Enables the transfer of coenzyme A from one side of a membrane to the other. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	got7fsn_ti	coenzyme A transporter activity													molecular_function											owl:Class	
GO:0035349	biolink:NamedThing	coenzyme A transmembrane transport	The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	got7fsn_ti	coenzyme A membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:44:33Z						biological_process											owl:Class	
GO:0140196	biolink:NamedThing	positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.	got7fsn_ti							pg	2018-02-15T19:13:29Z						biological_process											owl:Class	
GO:0044168	biolink:NamedThing	host cell rough endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface.	got7fsn_ti	host rough endoplasmic reticulum						jl	2009-09-04T11:23:28Z						cellular_component											owl:Class	
GO:1905083	biolink:NamedThing	negative regulation of mitochondrial translational elongation	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation.	got7fsn_ti	down regulation of mitochondrial translation elongation|downregulation of mitochondrial translational elongation|down regulation of mitochondrial translational elongation|negative regulation of mitochondrial translation elongation|inhibition of mitochondrial translational elongation|down-regulation of mitochondrial translational elongation|downregulation of mitochondrial translation elongation|down-regulation of mitochondrial translation elongation|inhibition of mitochondrial translation elongation						hjd	2016-03-25T17:37:13Z						biological_process											owl:Class	
GO:0030127	biolink:NamedThing	COPII vesicle coat	One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.	got7fsn_ti														cellular_component											owl:Class	
GO:0098749	biolink:NamedThing	cerebellar neuron development	The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0046802	biolink:NamedThing	exit of virus from host cell nucleus by nuclear egress	The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.	got7fsn_ti	capsid egress|nuclear egress|nuclear egress of viral procapsid|egress of viral procapsid from host cell nucleus										GO:0039676	VZ:1952		biological_process											owl:Class	
GO:0005757	biolink:NamedThing	mitochondrial permeability transition pore complex	A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).	got7fsn_ti	mitochondrial PT pore complex|MPTP complex|PTPC													cellular_component											owl:Class	
GO:2000003	biolink:NamedThing	positive regulation of DNA damage checkpoint	Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint.	got7fsn_ti	positive regulation of DNA damage response, signal transduction resulting in cell cycle arrest						jl	2010-07-15T03:25:10Z						biological_process											owl:Class	
GO:0005456	biolink:NamedThing	CMP-N-acetylneuraminate transmembrane transporter activity	Enables the transfer of a CMP-N-acetylneuraminate from one side of a membrane to the other.	got7fsn_ti	CMP-sialic acid transmembrane transporter activity											Reactome:R-HSA-727807|Reactome:R-HSA-5651942		molecular_function											owl:Class	
GO:0015782	biolink:NamedThing	CMP-N-acetylneuraminate transmembrane transport	The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	CMP-N-acetylneuraminate transport|CMP-sialic acid transport													biological_process											owl:Class	
GO:1905101	biolink:NamedThing	negative regulation of apoptosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly.	got7fsn_ti	down regulation of apoptosome formation|down regulation of apoptosome assembly|inhibition of apoptosome assembly|downregulation of apoptosome formation|negative regulation of apoptosome formation|down-regulation of apoptosome formation|downregulation of apoptosome assembly|down-regulation of apoptosome assembly|inhibition of apoptosome formation						bc	2016-04-04T08:57:51Z						biological_process											owl:Class	
GO:0015080	biolink:NamedThing	silver ion transmembrane transporter activity	Enables the transfer of silver (Ag) ions from one side of a membrane to the other.	got7fsn_ti	silver transporter activity													molecular_function											owl:Class	
GO:1902601	biolink:NamedThing	silver ion transmembrane transport	The directed movement of silver ion across a membrane.	got7fsn_ti	silver transmembrane transport						pr	2013-12-20T11:08:46Z						biological_process											owl:Class	
GO:0043254	biolink:NamedThing	regulation of protein-containing complex assembly	Any process that modulates the frequency, rate or extent of protein complex assembly.	got7fsn_ti	regulation of protein complex assembly													biological_process											owl:Class	
GO:0110039	biolink:NamedThing	positive regulation of nematode male tail tip morphogenesis	Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis.	got7fsn_ti							kmv	2017-07-24T20:32:58Z						biological_process											owl:Class	
GO:0045690	biolink:NamedThing	positive regulation of antipodal cell differentiation	Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation.	got7fsn_ti	upregulation of antipodal cell differentiation|stimulation of antipodal cell differentiation|up regulation of antipodal cell differentiation|up-regulation of antipodal cell differentiation|activation of antipodal cell differentiation													biological_process											owl:Class	
GO:0035645	biolink:NamedThing	enteric smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.	got7fsn_ti	intestinal smooth muscle cell differentiation						bf	2011-01-21T02:58:58Z						biological_process											owl:Class	
GO:0005368	biolink:NamedThing	taurine transmembrane transporter activity	Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats.	got7fsn_ti														molecular_function											owl:Class	
GO:0070719	biolink:NamedThing	alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex	A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.	got7fsn_ti	PDGFRA-PLC-gamma-1-PI3K-SHP-2 complex, PDGF stimulated						mah	2009-06-10T05:04:20Z						cellular_component											owl:Class	
GO:0045028	biolink:NamedThing	G protein-coupled purinergic nucleotide receptor activity	Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	purinergic nucleotide receptor activity, G protein coupled|G protein coupled purinergic nucleotide receptor activity|P2Y receptor|G-protein coupled purinergic nucleotide receptor activity|P2Y|purinergic nucleotide receptor activity, G-protein coupled													molecular_function											owl:Class	
GO:0000943	biolink:NamedThing	retrotransposon nucleocapsid	A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog.	got7fsn_ti	VLP|Virus-like particle											Wikipedia:Virus-like_particle		cellular_component											owl:Class	
GO:0019855	biolink:NamedThing	calcium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a calcium channel.	got7fsn_ti														molecular_function											owl:Class	
GO:1902428	biolink:NamedThing	negative regulation of water channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity.	got7fsn_ti	downregulation of aquaporin|down regulation of aquaporin|inhibition of water channel activity|inhibition of aquaporin|negative regulation of aquaporin|downregulation of water channel activity|down-regulation of aquaporin|down regulation of water channel activity|down-regulation of water channel activity						bf	2013-09-23T12:56:40Z						biological_process											owl:Class	
GO:0005632	biolink:NamedThing	inner layer of spore wall	Either of the two innermost layers of the spore wall, as described in Saccharomyces.	got7fsn_ti														cellular_component											owl:Class	
GO:0046327	biolink:NamedThing	glycerol biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate.	got7fsn_ti	glyceroneogenesis|glycerol synthesis from pyruvate|glycerol formation from pyruvate|glycerol anabolism from pyruvate													biological_process											owl:Class	
GO:0019432	biolink:NamedThing	triglyceride biosynthetic process	The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.	got7fsn_ti	triglyceride anabolism|triglyceride formation|triglyceride biosynthesis|triglyceride synthesis|triacylglycerol biosynthetic process|triacylglycerol biosynthesis											MetaCyc:TRIGLSYN-PWY		biological_process											owl:Class	
GO:0060633	biolink:NamedThing	negative regulation of transcription initiation from RNA polymerase II promoter	Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.	got7fsn_ti							dph	2009-05-18T03:11:26Z						biological_process											owl:Class	
GO:0071916	biolink:NamedThing	dipeptide transmembrane transporter activity	Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.	got7fsn_ti	dipeptide transporter activity						mah	2010-09-24T10:32:36Z			GO:0042936			molecular_function											owl:Class	
GO:0035442	biolink:NamedThing	dipeptide transmembrane transport	The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.	got7fsn_ti	dipeptide membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-13T09:18:33Z						biological_process											owl:Class	
GO:0035033	biolink:NamedThing	histone deacetylase regulator activity	Binds to and modulates the activity of histone deacetylase.	got7fsn_ti					See also the molecular function term 'histone deacetylase activity ; GO:0004407'.									molecular_function											owl:Class	
GO:0031063	biolink:NamedThing	regulation of histone deacetylation	Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones.	got7fsn_ti														biological_process											owl:Class	
GO:0103116	biolink:NamedThing	ABC-type D-galactofuranose transporter	Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O <=> alpha-D-galactofuranose + hydrogenphosphate + ADP + H+.	got7fsn_ti	ATP-dependent alpha-D-galactofuranose transporter activity|alpha-D-galactofuranose transporter activity|ATPase-coupled alpha-D-galactofuranose transporter activity											EC:7.5.2.9|RHEA:61716|MetaCyc:TRANS-RXN0-491		molecular_function											owl:Class	
GO:0033215	biolink:NamedThing	reductive iron assimilation	A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins.	got7fsn_ti	iron assimilation by reduction and transport													biological_process											owl:Class	
GO:0006587	biolink:NamedThing	serotonin biosynthetic process from tryptophan	The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	got7fsn_ti	serotonin synthesis from tryptophan|serotonin anabolism from tryptophan|serotonin formation from tryptophan													biological_process											owl:Class	
GO:0098878	biolink:NamedThing	neurotransmitter receptor complex	Any protein complex that is capable of functioning as a neurotransmitter receptor.	got7fsn_ti														cellular_component											owl:Class	
GO:0015546	biolink:NamedThing	sulfathiazole transmembrane transporter activity	Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group.	got7fsn_ti	sulphathiazole transporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:1902599	biolink:NamedThing	sulfathiazole transmembrane transport	The directed movement of sulfathiazole across a membrane.	got7fsn_ti	sulfathiazole transport|sulphathiazole transport						pr	2013-12-20T11:08:28Z			GO:0015906			biological_process											owl:Class	
GO:2000055	biolink:NamedThing	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.	got7fsn_ti	positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|positive regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|positive regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification						jl	2010-08-20T01:13:40Z						biological_process											owl:Class	
GO:0098654	biolink:NamedThing	CENP-A recruiting complex	A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere.	got7fsn_ti	MIS18 complex													cellular_component											owl:Class	
GO:0034426	biolink:NamedThing	etioplast membrane	Either of the lipid bilayers that surround a etioplast and form the etioplast envelope.	got7fsn_ti														cellular_component											owl:Class	
GO:0001929	biolink:NamedThing	negative regulation of exocyst assembly	Any process that stops, prevents, or reduces the rate or extent of exocyst assembly.	got7fsn_ti	down regulation of exocyst assembly|down-regulation of exocyst assembly|downregulation of exocyst assembly|inhibition of exocyst assembly													biological_process											owl:Class	
GO:0071367	biolink:NamedThing	cellular response to brassinosteroid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.	got7fsn_ti							mah	2009-12-11T03:13:33Z						biological_process											owl:Class	
GO:1905519	biolink:NamedThing	negative regulation of presynaptic active zone assembly	Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly.	got7fsn_ti	down-regulation of pre-synaptic active zone assembly|down-regulation of presynaptic active zone formation|down regulation of presynaptic active zone formation|inhibition of pre-synaptic active zone formation|down regulation of presynaptic active zone assembly|inhibition of presynaptic active zone formation|down regulation of pre-synaptic active zone component formation|downregulation of presynaptic active zone assembly|down-regulation of pre-synaptic active zone component assembly|down-regulation of presynaptic active zone assembly|downregulation of presynaptic active zone formation|down-regulation of pre-synaptic active zone formation|negative regulation of presynaptic active zone formation|down regulation of pre-synaptic active zone assembly|negative regulation of pre-synaptic active zone component assembly|negative regulation of pre-synaptic active zone formation|inhibition of presynaptic active zone assembly|negative regulation of pre-synaptic active zone component formation|downregulation of pre-synaptic active zone component formation|inhibition of pre-synaptic active zone assembly|negative regulation of pre-synaptic active zone assembly|down-regulation of pre-synaptic active zone component formation|down regulation of pre-synaptic active zone component assembly|down regulation of pre-synaptic active zone formation|inhibition of pre-synaptic active zone component formation|downregulation of pre-synaptic active zone component assembly|downregulation of pre-synaptic active zone formation|downregulation of pre-synaptic active zone assembly|inhibition of pre-synaptic active zone component assembly						rl	2016-10-01T09:38:00Z						biological_process											owl:Class	
GO:0045146	biolink:NamedThing	initiation of acetate catabolic process by acetate	The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.	got7fsn_ti	initiation of acetate breakdown by acetate|initiation of acetate degradation by acetate													biological_process											owl:Class	
GO:0019294	biolink:NamedThing	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.	got7fsn_ti	KDO biosynthesis|keto-3-deoxy-D-manno-octulosonic acid anabolism|keto-3-deoxy-D-manno-octulosonic acid biosynthesis|keto-3-deoxy-D-manno-octulosonic acid formation|ketodeoxyoctanoate biosynthetic process|KDO biosynthetic process|keto-3-deoxy-D-manno-octulosonic acid synthesis											MetaCyc:KDOSYN-PWY		biological_process											owl:Class	
NCBITaxon:1117	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031279	biolink:NamedThing	regulation of cyclase activity	Any process that modulates the frequency, rate or extent of cyclase activity.	got7fsn_ti														biological_process											owl:Class	
GO:0010142	biolink:NamedThing	farnesyl diphosphate biosynthetic process, mevalonate pathway	The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols.	got7fsn_ti	acetate-mevalonate pathway|farnesyl diphosphate anabolism, mevalonate pathway|farnesyl diphosphate synthesis, mevalonate pathway|Ac-MVA pathway|farnesyl diphosphate formation, mevalonate pathway|isoprenoid pathway											MetaCyc:PWY-922		biological_process											owl:Class	
GO:0016114	biolink:NamedThing	terpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.	got7fsn_ti	terpenoid formation|terpenoid biosynthesis|terpenoid anabolism|terpenoid synthesis											Wikipedia:Terpenoid		biological_process											owl:Class	
GO:1904342	biolink:NamedThing	negative regulation of colon smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction.	got7fsn_ti	down regulation of colon smooth muscle contraction|inhibition of colon smooth muscle contraction|down-regulation of colon smooth muscle contraction|downregulation of colon smooth muscle contraction						sl	2015-06-11T21:17:05Z						biological_process											owl:Class	
GO:1901725	biolink:NamedThing	regulation of histone deacetylase activity	Any process that modulates the frequency, rate or extent of histone deacetylase activity.	got7fsn_ti							rl	2013-01-07T09:14:12Z						biological_process											owl:Class	
GO:0045253	biolink:NamedThing	pyruvate dehydrogenase (lipoamide) phosphatase complex	A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.	got7fsn_ti					See also the cellular component term 'cytosolic pyruvate dehydrogenase complex ; GO:0045250'.									cellular_component											owl:Class	
GO:0000817	biolink:NamedThing	COMA complex	A kinetochore multiprotein complex that bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly. In yeast, consists of Ctf19p, Okp1p, Mcm21p, and Ame1p.	got7fsn_ti	Ctf19p-Okp1p-Mcm1p-Ame1p complex	https://github.com/geneontology/go-ontology/issues/21126												cellular_component											owl:Class	
GO:0045945	biolink:NamedThing	positive regulation of transcription by RNA polymerase III	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III.	got7fsn_ti	up-regulation of transcription from RNA polymerase III promoter|stimulation of transcription from RNA polymerase III promoter|positive regulation of transcription from Pol III promoter|up regulation of transcription from RNA polymerase III promoter|activation of transcription from RNA polymerase III promoter|positive regulation of transcription from RNA polymerase III promoter|upregulation of transcription from RNA polymerase III promoter													biological_process											owl:Class	
GO:0071058	biolink:NamedThing	alpha3-beta1 integrin-CD151 complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151.	got7fsn_ti	ITGA3-ITGB1-CD151 complex						mah	2009-11-03T04:00:39Z						cellular_component											owl:Class	
GO:0002399	biolink:NamedThing	MHC class II protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:1903594	biolink:NamedThing	negative regulation of histamine secretion by mast cell	Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell.	got7fsn_ti	downregulation of histamine secretion by mast cell|down regulation of histamine secretion by mast cell|down-regulation of histamine secretion by mast cell|inhibition of histamine secretion by mast cell						als	2014-11-06T13:19:18Z						biological_process											owl:Class	
GO:0035932	biolink:NamedThing	aldosterone secretion	The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.	got7fsn_ti							bf	2011-07-20T01:06:24Z						biological_process											owl:Class	
GO:0010061	biolink:NamedThing	regulation of trichoblast fate specification	Any process that modulates trichoblast fate specification.	got7fsn_ti														biological_process											owl:Class	
GO:0051484	biolink:NamedThing	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.	got7fsn_ti	isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid biosynthesis|isopentenyl diphosphate synthesis, mevalonate-independent pathway, during terpenoid synthesis|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway involved in terpenoid biosynthetic process|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway, during terpenoid biosynthetic process|isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid formation|isopentenyl diphosphate anabolism, mevalonate-independent pathway, during terpenoid anabolism											MetaCyc:NONMEVIPP-PWY		biological_process											owl:Class	
GO:0051483	biolink:NamedThing	terpenoid biosynthetic process, mevalonate-independent	The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate.	got7fsn_ti	mevalonate-independent terpene biosynthetic process|terpenoid synthesis, mevalonate-independent|mevalonate-independent terpenoid biosynthesis|terpene biosynthetic process, mevalonate-independent|terpene biosynthesis, mevalonate-independent|mevalonate-independent terpene biosynthesis|terpenoid anabolism, mevalonate-independent|mevalonate-independent terpenoid biosynthetic process|terpenoid formation, mevalonate-independent													biological_process											owl:Class	
GO:0007510	biolink:NamedThing	cardioblast cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti														biological_process											owl:Class	
GO:0003229	biolink:NamedThing	ventricular cardiac muscle tissue development	The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.	got7fsn_ti	ventricular myocardium development						dph	2009-10-13T10:56:01Z						biological_process											owl:Class	
GO:0033031	biolink:NamedThing	positive regulation of neutrophil apoptotic process	Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.	got7fsn_ti	stimulation of neutrophil apoptosis|up-regulation of neutrophil apoptosis|up regulation of neutrophil apoptosis|activation of neutrophil apoptosis|upregulation of neutrophil apoptosis|positive regulation of neutrophil apoptosis													biological_process											owl:Class	
GO:0140200	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate	An adrenergic receptor signaling pathway that modulates the frequency or rate of heart contraction.	got7fsn_ti							pg	2018-02-16T14:33:06Z						biological_process											owl:Class	
GO:0046765	biolink:NamedThing	viral budding from nuclear membrane	A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.	got7fsn_ti	viral budding from nuclear membrane by viral capsid envelopment|virus budding from nuclear membrane during viral capsid envelopment|virus budding from nuclear membrane|nuclear membrane viral budding during viral capsid envelopment|virus budding from nuclear membrane by viral capsid envelopment|nuclear membrane viral budding|viral budding from nuclear membrane during viral capsid envelopment										GO:0046749			biological_process											owl:Class	
GO:1905774	biolink:NamedThing	regulation of DNA helicase activity	Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity.	got7fsn_ti	regulation of ATP-dependent DNA helicase activity						rb	2013-10-15T21:19:52Z			GO:1902449			biological_process											owl:Class	
GO:0099084	biolink:NamedThing	postsynaptic specialization organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane.	got7fsn_ti	post synaptic specialization organization|post-synaptic specialization organization|postsynaptic specialization organisation						pr	2011-07-27T05:17:12Z						biological_process											owl:Class	
GO:2000320	biolink:NamedThing	negative regulation of T-helper 17 cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.	got7fsn_ti	negative regulation of T-helper 17 cell development						mah	2011-01-18T01:44:31Z						biological_process											owl:Class	
GO:1903978	biolink:NamedThing	regulation of microglial cell activation	Any process that modulates the frequency, rate or extent of microglial cell activation.	got7fsn_ti							nc	2015-03-02T15:17:33Z						biological_process											owl:Class	
GO:0045053	biolink:NamedThing	protein retention in Golgi apparatus	The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.	got7fsn_ti	protein-Golgi retention|maintenance of protein location in Golgi apparatus|retention of protein in Golgi													biological_process											owl:Class	
GO:0022025	biolink:NamedThing	leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment	Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	got7fsn_ti	leukemia inhibitory factor signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:1903183	biolink:NamedThing	negative regulation of SUMO transferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity.	got7fsn_ti	negative regulation of SUMO conjugating enzyme activity|down regulation of SMT3 conjugating enzyme|down-regulation of SUMO ligase activity|downregulation of SMT3 conjugating enzyme|inhibition of SMT3 conjugating enzyme|down-regulation of SUMO conjugating enzyme activity|down regulation of SUMO ligase activity|inhibition of SUMO conjugating enzyme activity|downregulation of SUMO conjugating enzyme activity|down-regulation of SMT3 conjugating enzyme|down regulation of SUMO conjugating enzyme activity|negative regulation of SMT3 conjugating enzyme|inhibition of SUMO ligase activity|downregulation of SUMO ligase activity						bf	2014-07-14T14:01:46Z						biological_process											owl:Class	
GO:0050823	biolink:NamedThing	peptide antigen stabilization	Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.	got7fsn_ti	peptide antigen stabilization activity													biological_process											owl:Class	
GO:1901588	biolink:NamedThing	dendritic microtubule	Any microtubule in a dendrite, a neuron projection.	got7fsn_ti	microtubulus of dendrite|microtubule of dendrite						pr	2012-11-07T14:37:30Z				NIF_Subcellular:sao110773650		cellular_component											owl:Class	
GO:1902963	biolink:NamedThing	negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.	got7fsn_ti	inhibition of metalloendoprotease activity involved in APP catabolic process|negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoproteinase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|down-regulation of metalloendoproteinase activity involved in APP catabolic process|down regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down-regulation of metalloendoprotease activity involved in APP catabolism|down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoprotease activity involved in APP catabolism|inhibition of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoproteinase activity involved in APP catabolism|negative regulation of metalloendoproteinase activity involved in APP catabolism|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|down regulation of metalloendoprotease activity involved in APP catabolism|inhibition of metalloendoproteinase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in APP catabolic process|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|inhibition of metalloendoproteinase activity involved in amyloid precursor protein breakdown|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|negative regulation of metalloendopeptidase activity involved in APP catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|inhibition of metalloendopeptidase activity involved in APP catabolism|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|downregulation of metalloendoproteinase activity involved in APP catabolism|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendopeptidase activity involved in APP catabolic process|downregulation of metalloendoprotease activity involved in APP catabolism|down regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|inhibition of metalloendoprotease activity involved in APP catabolism|negative regulation of metalloendopeptidase activity involved in APP catabolism|inhibition of metalloendopeptidase activity involved in APP catabolic process|downregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|inhibition of metalloendoprotease activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down regulation of metalloendoprotease activity involved in APP catabolic process|down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolism|inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|inhibition of metalloendoproteinase activity involved in APP catabolic process|down regulation of metalloendopeptidase activity involved in APP catabolic process|down-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|down regulation of metalloendopeptidase activity involved in APP catabolism|inhibition of metalloendoproteinase activity involved in amyloid precursor protein degradation|down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|inhibition of metalloendopeptidase activity involved in amyloid precursor protein degradation|inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoprotease activity involved in amyloid precursor protein degradation|down regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|downregulation of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolism|downregulation of metalloendopeptidase activity involved in APP catabolic process|down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoproteinase activity involved in APP catabolic process|downregulation of metalloendoproteinase activity involved in APP catabolic process|downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoprotease activity involved in APP catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein degradation|downregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolic process|negative regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|downregulation of metalloendopeptidase activity involved in APP catabolism|down-regulation of metalloendopeptidase activity involved in APP catabolism						sjp	2014-05-06T09:12:01Z						biological_process											owl:Class	
GO:0045041	biolink:NamedThing	protein import into mitochondrial intermembrane space	The import of proteins into the space between the inner and outer mitochondrial membranes.	got7fsn_ti	protein import into mitochondrial IMS|mitochondrial intermembrane space protein import|protein transport into mitochondrial intermembrane space|protein import into mitochondrial intermembrane space, nonconservative|protein import into mitochondrial intermembrane space, direct|protein transport into mitochondrial IMS										GO:0045043|GO:0045044			biological_process											owl:Class	
GO:0060224	biolink:NamedThing	regulation of retinal rod cell fate commitment	Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.	got7fsn_ti														biological_process											owl:Class	
GO:0042720	biolink:NamedThing	mitochondrial inner membrane peptidase complex	Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.	got7fsn_ti	IMP|mitochondrion inner membrane peptidase complex													cellular_component											owl:Class	
GO:0004105	biolink:NamedThing	choline-phosphate cytidylyltransferase activity	Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline.	got7fsn_ti	CTP-phosphocholine cytidylyltransferase activity|CTP:choline-phosphate cytidylyltransferase activity|CTP:phosphocholine cytidylyltransferase activity|CDP-choline synthetase activity|CTP:phosphorylcholine cytidylyltransferase activity|phosphorylcholine cytidylyltransferase activity|cytidine diphosphocholine pyrophosphorylase activity|phosphorylcholine:CTP cytidylyltransferase activity|choline phosphate cytidylyltransferase activity|CDP-choline pyrophosphorylase activity|phosphocholine cytidylyltransferase activity|phosphorylcholine transferase activity											Reactome:R-HSA-1483081|EC:2.7.7.15|MetaCyc:2.7.7.15-RXN|RHEA:18997		molecular_function											owl:Class	
GO:0060833	biolink:NamedThing	Wnt signaling pathway involved in animal/vegetal axis specification	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte.	got7fsn_ti	Wnt receptor signalling pathway involved in animal/vegetal axis specification|Wnt- activated signaling pathway involved in animal/vegetal axis specification|Wnt receptor signaling pathway involved in animal/vegetal axis specification						dph	2009-08-11T03:20:39Z						biological_process											owl:Class	
GO:0003042	biolink:NamedThing	vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure	A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.	got7fsn_ti	vasoconstriction of artery during carotid body chemoreceptor response to lowering of systemic arterial blood pressure													biological_process											owl:Class	
CHEBI:27570	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034693	biolink:NamedThing	U11/U12 snRNP	A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins.	got7fsn_ti	snRNP U11/U12|18S U11/U12 snRNP													cellular_component											owl:Class	
GO:0015086	biolink:NamedThing	cadmium ion transmembrane transporter activity	Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.	got7fsn_ti	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|zinc, cadmium uptake permease activity													molecular_function											owl:Class	
GO:1905879	biolink:NamedThing	regulation of oogenesis	Any process that modulates the frequency, rate or extent of oogenesis.	got7fsn_ti	regulation of ovum development						hbye	2017-01-31T09:31:05Z						biological_process											owl:Class	
GO:0001834	biolink:NamedThing	trophectodermal cell proliferation	The proliferation of cells in the trophectoderm.	got7fsn_ti	trophectoderm cell proliferation				See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.									biological_process											owl:Class	
GO:0051894	biolink:NamedThing	positive regulation of focal adhesion assembly	Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.	got7fsn_ti	up regulation of focal adhesion formation|activation of focal adhesion formation|upregulation of focal adhesion formation|up-regulation of focal adhesion formation|stimulation of focal adhesion formation													biological_process											owl:Class	
GO:0021625	biolink:NamedThing	oculomotor nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	got7fsn_ti	CN III maturation													biological_process											owl:Class	
GO:0061170	biolink:NamedThing	negative regulation of hair follicle placode formation	Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.	got7fsn_ti							dph	2010-06-25T01:10:48Z						biological_process											owl:Class	
GO:0046599	biolink:NamedThing	regulation of centriole replication	Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.	got7fsn_ti														biological_process											owl:Class	
GO:0071466	biolink:NamedThing	cellular response to xenobiotic stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	cellular response to drug	https://github.com/geneontology/go-ontology/issues/19460					mah	2009-12-18T11:38:48Z			GO:0035690			biological_process											owl:Class	
GO:2000267	biolink:NamedThing	negative regulation of blood coagulation, intrinsic pathway	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway.	got7fsn_ti							mah	2010-11-23T11:45:46Z						biological_process											owl:Class	
GO:2000006	biolink:NamedThing	regulation of metanephric comma-shaped body morphogenesis	Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis.	got7fsn_ti							jl	2010-07-30T02:17:12Z						biological_process											owl:Class	
GO:1902910	biolink:NamedThing	positive regulation of melanosome transport	Any process that activates or increases the frequency, rate or extent of melanosome transport.	got7fsn_ti	up regulation of melanosome transport|activation of melanosome transport|upregulation of melanosome transport|up-regulation of melanosome transport						als	2014-04-17T11:40:34Z						biological_process											owl:Class	
GO:0019829	biolink:NamedThing	ATPase-coupled cation transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).	got7fsn_ti	ATP-dependent cation transmembrane transporter activity|plasma membrane cation-transporting ATPase|cation-transporting ATPase activity|cation ABC transporter											Reactome:R-HSA-5251989|Reactome:R-HSA-5692480		molecular_function											owl:Class	
GO:2000045	biolink:NamedThing	regulation of G1/S transition of mitotic cell cycle	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.	got7fsn_ti					Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'.		tb	2010-08-19T09:10:56Z						biological_process											owl:Class	
GO:0071425	biolink:NamedThing	hematopoietic stem cell proliferation	The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.	got7fsn_ti	hemopoietic stem cell proliferation						mah	2009-12-16T10:22:52Z						biological_process											owl:Class	
GO:0048057	biolink:NamedThing	R3/R4 development	The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.	got7fsn_ti														biological_process											owl:Class	
GO:0010868	biolink:NamedThing	negative regulation of triglyceride biosynthetic process	Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.	got7fsn_ti	negative regulation of triacylglycerol biosynthetic process													biological_process											owl:Class	
GO:0000220	biolink:NamedThing	vacuolar proton-transporting V-type ATPase, V0 domain	The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.	got7fsn_ti	vacuolar hydrogen ion-transporting ATPase V0 domain				Note that this domain often consists of five subunits, although in some mammalian tissues it may have an additional subunit.									cellular_component											owl:Class	
GO:0075030	biolink:NamedThing	modulation of formation of symbiont germ tube hook structure for appressorium development	Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation.	got7fsn_ti	regulation of formation of symbiont germ tube hook structure on or near host|modulation of symbiont germ tube hook structure formation on or near host|modulation of germ tube tip of symbiont on or near the exterior of host													biological_process											owl:Class	
CL:0000775	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904445	biolink:NamedThing	negative regulation of establishment of Sertoli cell barrier	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier.	got7fsn_ti	down regulation of establishment of Sertoli cell barrier|downregulation of establishment of BTB|inhibition of establishment of blood-testis barrier|down-regulation of establishment of BTB|downregulation of establishment of SCB|inhibition of establishment of BTB|inhibition of establishment of Sertoli cell barrier|negative regulation of establishment of BTB|downregulation of establishment of blood-testis barrier|down regulation of establishment of SCB|down regulation of establishment of BTB|down-regulation of establishment of SCB|downregulation of establishment of Sertoli cell barrier|negative regulation of establishment of blood-testis barrier|inhibition of establishment of SCB|down-regulation of establishment of Sertoli cell barrier|down regulation of establishment of blood-testis barrier|down-regulation of establishment of blood-testis barrier|negative regulation of establishment of SCB						sl	2015-07-06T16:00:48Z						biological_process											owl:Class	
GO:0044726	biolink:NamedThing	protection of DNA demethylation of female pronucleus	The protection of the maternal genome from DNA demethylation in the zygote following fertilization.	got7fsn_ti							jl	2012-10-24T14:10:36Z						biological_process											owl:Class	
GO:1901670	biolink:NamedThing	negative regulation of superoxide dismutase activity	Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity.	got7fsn_ti	inhibition of cuprein|downregulation of hemocuprein|down-regulation of Mn, Fe superoxide dismutase|inhibition of manganese superoxide oxidoreductase|inhibition of SOD-3|down-regulation of superoxide dismutase activity|negative regulation of zinc superoxide oxidoreductase|down-regulation of superoxide dismutase II|down-regulation of manganese superoxide oxidoreductase|negative regulation of SOD-4|downregulation of iron superoxide oxidoreductase|downregulation of SODF|inhibition of nickel superoxide oxidoreductase|down-regulation of manganese superoxide dismutase activity|down regulation of superoxide:superoxide oxidoreductase activity|downregulation of SOD-4|negative regulation of superoxide dismutase II|downregulation of hepatocuprein|down-regulation of Mn-SOD|negative regulation of manganese superoxide dismutase activity|negative regulation of Fe-SOD|down regulation of Fe-SOD|downregulation of SOD-3|negative regulation of iron superoxide oxidoreductase|negative regulation of iron superoxide dismutase activity|down-regulation of copper, zinc superoxide dismutase activity|negative regulation of Cu-Zn superoxide dismutase activity|negative regulation of SOD-3|down-regulation of cuprein|down regulation of cuprein|down-regulation of SODF|inhibition of Mn-SOD|down-regulation of nickel superoxide dismutase activity|negative regulation of Cu,Zn-SOD|down-regulation of iron superoxide oxidoreductase|inhibition of superoxide dismutase activity|down regulation of superoxide dismutase activity|inhibition of superoxide dismutase II|down regulation of SOD-3|negative regulation of hemocuprein|down regulation of Mn-SOD|down-regulation of cytocuprein|negative regulation of copper, zinc superoxide dismutase activity|down regulation of SOD-1|down regulation of erythrocuprein|negative regulation of superoxide:superoxide oxidoreductase activity|down regulation of superoxide dismutase II|negative regulation of erythrocuprein|downregulation of nickel superoxide dismutase activity|down-regulation of superoxide dismutase I|down-regulation of SOD-1|downregulation of Fe-SOD|down regulation of SOD|negative regulation of superoxide dismutase I|inhibition of SODS|negative regulation of Mn-SOD|inhibition of Cu,Zn-SOD|downregulation of copper, zinc superoxide dismutase activity|down-regulation of SODS|downregulation of Mn-SOD|down regulation of manganese superoxide dismutase activity|downregulation of iron superoxide dismutase activity|down regulation of zinc superoxide oxidoreductase|inhibition of hemocuprein|downregulation of Mn, Fe superoxide dismutase|inhibition of SODF|inhibition of zinc superoxide oxidoreductase|down regulation of iron superoxide oxidoreductase|down regulation of nickel superoxide oxidoreductase|inhibition of hepatocuprein|negative regulation of manganese superoxide oxidoreductase|downregulation of superoxide dismutase I|downregulation of zinc superoxide oxidoreductase|negative regulation of SOD|negative regulation of SOD-2|downregulation of manganese superoxide dismutase activity|negative regulation of SOD-1|negative regulation of hepatocuprein|downregulation of nickel superoxide oxidoreductase|downregulation of cuprein|inhibition of superoxide:superoxide oxidoreductase activity|down regulation of SOD-2|downregulation of Cu-Zn superoxide dismutase activity|down-regulation of SOD-2|down regulation of iron superoxide dismutase activity|down-regulation of hemocuprein|down-regulation of nickel superoxide oxidoreductase|inhibition of iron superoxide dismutase activity|inhibition of SOD-4|down-regulation of superoxide:superoxide oxidoreductase activity|negative regulation of nickel superoxide oxidoreductase|inhibition of superoxide dismutase I|inhibition of Fe-SOD|negative regulation of cuprein|negative regulation of nickel superoxide dismutase activity|inhibition of Cu-Zn superoxide dismutase activity|inhibition of iron superoxide oxidoreductase|down regulation of Cu,Zn-SOD|inhibition of Mn, Fe superoxide dismutase|down-regulation of zinc superoxide oxidoreductase|downregulation of SOD-1|down regulation of SODF|downregulation of cytocuprein|inhibition of copper, zinc superoxide dismutase activity|downregulation of superoxide dismutase activity|down regulation of manganese superoxide oxidoreductase|down-regulation of SOD-3|down regulation of ferrisuperoxide dismutase activity|down regulation of cytocuprein|down regulation of nickel superoxide dismutase activity|negative regulation of cytocuprein|downregulation of erythrocuprein|down-regulation of SOD|downregulation of SOD|down-regulation of hepatocuprein|down regulation of hemocuprein|negative regulation of ferrisuperoxide dismutase activity|down regulation of SODS|downregulation of manganese superoxide oxidoreductase|down regulation of copper, zinc superoxide dismutase activity|down-regulation of Fe-SOD|down regulation of Cu-Zn superoxide dismutase activity|negative regulation of SODF|downregulation of SOD-2|downregulation of SODS|inhibition of ferrisuperoxide dismutase activity|down regulation of SOD-4|inhibition of manganese superoxide dismutase activity|down-regulation of SOD-4|downregulation of Cu,Zn-SOD|down-regulation of ferrisuperoxide dismutase activity|down regulation of superoxide dismutase I|inhibition of SOD|down regulation of Mn, Fe superoxide dismutase|negative regulation of SODS|inhibition of nickel superoxide dismutase activity|down-regulation of erythrocuprein|inhibition of SOD-2|negative regulation of Mn, Fe superoxide dismutase|inhibition of cytocuprein|inhibition of SOD-1|downregulation of superoxide:superoxide oxidoreductase activity|down-regulation of iron superoxide dismutase activity|downregulation of superoxide dismutase II|down-regulation of Cu,Zn-SOD|down regulation of hepatocuprein|inhibition of erythrocuprein|down-regulation of Cu-Zn superoxide dismutase activity|downregulation of ferrisuperoxide dismutase activity						tb	2012-11-21T21:36:07Z						biological_process											owl:Class	
GO:1990898	biolink:NamedThing	meiotic DNA double-strand break clipping	The process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. Proteins involved in this process include the MRX/MRN complex and Sae2/Ctp1/RBBP8(CtIP).	got7fsn_ti							al	2015-11-10T17:12:27Z						biological_process											owl:Class	
GO:0032277	biolink:NamedThing	negative regulation of gonadotropin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.	got7fsn_ti	downregulation of gonadotropin secretion|negative regulation of gonadotrophin secretion|down regulation of gonadotropin secretion|down-regulation of gonadotropin secretion|inhibition of gonadotropin secretion													biological_process											owl:Class	
GO:2000087	biolink:NamedThing	regulation of mesonephric glomerulus development	Any process that modulates the frequency, rate or extent of mesonephric glomerulus development.	got7fsn_ti							dph	2010-09-03T06:09:19Z						biological_process											owl:Class	
GO:0034246	biolink:NamedThing	mitochondrial transcription factor activity	Interacting with the mitochondrial promoter DNA to modulate transcription by the mitochondrial RNA polymerase.	got7fsn_ti	mitochondrial polymerase transcription factor activity|sequence-specific DNA binding mitochondrial RNA polymerase transcription factor activity|mitochondrial sequence-specific DNA binding transcription factor activity|transcription factor activity, mitochondrial proximal promoter sequence-specific binding|transcription factor activity, mitochondrial RNA polymerase core promoter sequence-specific DNA binding|mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity|mitochondrial sequence-specific DNA-binding transcription factor activity|mitochondrial DNA-binding transcription factor activity|mitochondrial RNA polymerase transcription factor activity, sequence-specific DNA binding|mitochondrial RNA polymerase binding promoter specificity activity|mitochondrial RNA polymerase promoter specificity activity|transcription factor activity, mitochondrial RNA polymerase core promoter proximal region sequence-specific binding|mitochondrial transcription initiation factor activity|mitochondrial RNA polymerase core promoter sequence-specific DNA binding transcription factor activity|mitochondrial transcription factor activity	https://github.com/geneontology/go-ontology/issues/14908|https://github.com/geneontology/go-ontology/issues/19891					krc	2011-01-27T01:55:21Z			GO:0001143|GO:0000998|GO:0001142|GO:0001144			molecular_function											owl:Class	
GO:0032786	biolink:NamedThing	positive regulation of DNA-templated transcription, elongation	Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.	got7fsn_ti	positive regulation of transcription elongation|activation of RNA elongation|up regulation of RNA elongation|positive regulation of transcription elongation, DNA-dependent|up-regulation of RNA elongation|positive regulation of transcriptional elongation|upregulation of RNA elongation|positive transcription elongation regulator activity|stimulation of RNA elongation|positive regulation of DNA-dependent transcription, elongation													biological_process											owl:Class	
GO:0005889	biolink:NamedThing	potassium:proton exchanging ATPase complex	A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.	got7fsn_ti	hydrogen/potassium-exchanging ATPase complex|hydrogen:potassium-exchanging ATPase complex|proton pump													cellular_component											owl:Class	
GO:0070334	biolink:NamedThing	alpha6-beta4 integrin-laminin 5 complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5.	got7fsn_ti	alpha6-beta4 integrin-laminin-332 complex|ITGA6-ITGB4-LAMA5 complex													cellular_component											owl:Class	
GO:0072597	biolink:NamedThing	maintenance of protein location in chloroplast	Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere.	got7fsn_ti							mah	2011-02-14T02:17:48Z						biological_process											owl:Class	
GO:1902226	biolink:NamedThing	regulation of macrophage colony-stimulating factor signaling pathway	Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.	got7fsn_ti	regulation of macrophage colony-stimulating factor signalling pathway|regulation of M-CSF signaling pathway						lb	2013-06-14T06:28:42Z						biological_process											owl:Class	
GO:0006963	biolink:NamedThing	positive regulation of antibacterial peptide biosynthetic process	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.	got7fsn_ti	stimulation of antibacterial peptide biosynthetic process|activation of antibacterial peptide biosynthetic process|up regulation of antibacterial peptide biosynthetic process|upregulation of antibacterial peptide biosynthetic process|antibacterial polypeptide induction|up-regulation of antibacterial peptide biosynthetic process|antibacterial peptide induction													biological_process											owl:Class	
GO:0015556	biolink:NamedThing	C4-dicarboxylate transmembrane transporter activity	Enables the transfer of C4-dicarboxylate from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015740	biolink:NamedThing	C4-dicarboxylate transport	The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms.	got7fsn_ti														biological_process											owl:Class	
GO:0098876	biolink:NamedThing	vesicle-mediated transport to the plasma membrane	The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.	got7fsn_ti														biological_process											owl:Class	
NCBITaxon:6073	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901248	biolink:NamedThing	positive regulation of lung ciliated cell differentiation	Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.	got7fsn_ti	up regulation of lung ciliated cell differentiation|activation of lung ciliated cell differentiation|upregulation of lung ciliated cell differentiation|up-regulation of lung ciliated cell differentiation						vk	2012-08-08T08:59:05Z						biological_process											owl:Class	
GO:1904747	biolink:NamedThing	positive regulation of apoptotic process involved in development	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.	got7fsn_ti	up-regulation of commitment to apoptosis involved in anatomical structure development|up regulation of activation of apoptosis involved in anatomical structure development|activation of induction of apoptosis by p53 involved in development of an anatomical structure|activation of apoptosis involved in development of an anatomical structure|up-regulation of induction of apoptosis involved in development of an anatomical structure|positive regulation of apoptosis signaling involved in development of an anatomical structure|up regulation of apoptotic program involved in anatomical structure development|activation of apoptotic program involved in anatomical structure development|up regulation of apoptosis involved in anatomical structure development|positive regulation of apoptotic cell death involved in anatomical structure development|up regulation of type I programmed cell death involved in development of an anatomical structure|upregulation of apoptosis signaling involved in anatomical structure development|up regulation of commitment to apoptosis involved in development of an anatomical structure|positive regulation of apoptosis involved in anatomical structure development|upregulation of commitment to apoptosis involved in development of an anatomical structure|up-regulation of commitment to apoptosis involved in development of an anatomical structure|positive regulation of apoptotic process involved in anatomical structure development|positive regulation of signaling (initiator) caspase activity involved in anatomical structure development|activation of apoptotic process involved in anatomical structure development|positive regulation of apoptotic programmed cell death involved in anatomical structure development|upregulation of apoptotic programmed cell death involved in anatomical structure development|upregulation of apoptosis involved in anatomical structure development|up-regulation of apoptosis signaling involved in development of an anatomical structure|activation of apoptotic programmed cell death involved in development of an anatomical structure|activation of apoptosis involved in anatomical structure development|activation of apoptotic cell death involved in development of an anatomical structure|upregulation of apoptosis involved in development of an anatomical structure|up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|up regulation of induction of apoptosis involved in anatomical structure development|positive regulation of induction of apoptosis by p53 involved in anatomical structure development|up regulation of apoptotic program involved in development of an anatomical structure|up regulation of apoptotic programmed cell death involved in development of an anatomical structure|activation of apoptotic process involved in development of an anatomical structure|activation of induction of apoptosis involved in development of an anatomical structure|positive regulation of type I programmed cell death involved in anatomical structure development|up-regulation of apoptotic programmed cell death involved in development of an anatomical structure|up-regulation of apoptotic cell death involved in development of an anatomical structure|up regulation of type I programmed cell death involved in anatomical structure development|upregulation of apoptosis signaling involved in development of an anatomical structure|upregulation of type I programmed cell death involved in development of an anatomical structure|upregulation of apoptotic process involved in anatomical structure development|upregulation of commitment to apoptosis involved in anatomical structure development|positive regulation of activation of apoptosis involved in anatomical structure development|up-regulation of apoptosis activator activity involved in development of an anatomical structure|up regulation of activation of apoptosis involved in development of an anatomical structure|up regulation of apoptotic cell death involved in development of an anatomical structure|positive regulation of commitment to apoptosis involved in anatomical structure development|up-regulation of apoptosis involved in development of an anatomical structure|positive regulation of apoptosis activator activity involved in anatomical structure development|up-regulation of type I programmed cell death involved in anatomical structure development|positive regulation of apoptotic cell death involved in development of an anatomical structure|activation of type I programmed cell death involved in development of an anatomical structure|activation of signaling (initiator) caspase activity involved in development of an anatomical structure|positive regulation of programmed cell death by apoptosis involved in anatomical structure development|upregulation of activation of apoptosis involved in development of an anatomical structure|positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure|up-regulation of apoptotic program involved in anatomical structure development|positive regulation of type I programmed cell death involved in development of an anatomical structure|upregulation of apoptotic cell death involved in development of an anatomical structure|activation of activation of apoptosis involved in development of an anatomical structure|activation of type I programmed cell death involved in anatomical structure development|upregulation of apoptotic process involved in development of an anatomical structure|upregulation of type I programmed cell death involved in anatomical structure development|upregulation of apoptotic process involved in development|up-regulation of induction of apoptosis involved in anatomical structure development|upregulation of apoptotic program involved in development of an anatomical structure|positive regulation of activation of apoptosis involved in development of an anatomical structure|upregulation of apoptosis activator activity involved in anatomical structure development|upregulation of apoptotic programmed cell death involved in development of an anatomical structure|upregulation of induction of apoptosis by p53 involved in anatomical structure development|activation of apoptosis activator activity involved in anatomical structure development|up regulation of apoptotic process involved in development|up-regulation of induction of apoptosis by p53 involved in anatomical structure development|upregulation of induction of apoptosis involved in anatomical structure development|activation of apoptotic program involved in development of an anatomical structure|upregulation of induction of apoptosis involved in development of an anatomical structure|upregulation of apoptotic program involved in anatomical structure development|up regulation of apoptosis activator activity involved in anatomical structure development|up regulation of induction of apoptosis involved in development of an anatomical structure|positive regulation of induction of apoptosis involved in anatomical structure development|up regulation of apoptosis activator activity involved in development of an anatomical structure|up regulation of apoptosis signaling involved in anatomical structure development|up regulation of apoptotic cell death involved in anatomical structure development|positive regulation of apoptosis activator activity involved in development of an anatomical structure|up-regulation of programmed cell death by apoptosis involved in anatomical structure development|up regulation of signaling (initiator) caspase activity involved in anatomical structure development|upregulation of activation of apoptosis involved in anatomical structure development|up regulation of commitment to apoptosis involved in anatomical structure development|upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure|up-regulation of apoptotic programmed cell death involved in anatomical structure development|up-regulation of apoptotic process involved in anatomical structure development|up regulation of induction of apoptosis by p53 involved in development of an anatomical structure|positive regulation of commitment to apoptosis involved in development of an anatomical structure|upregulation of signaling (initiator) caspase activity involved in anatomical structure development|up regulation of apoptosis involved in development of an anatomical structure|up regulation of apoptotic programmed cell death involved in anatomical structure development|up-regulation of apoptosis signaling involved in anatomical structure development|activation of apoptosis activator activity involved in development of an anatomical structure|positive regulation of apoptotic program involved in anatomical structure development|activation of apoptotic process involved in development|activation of programmed cell death by apoptosis involved in development of an anatomical structure|positive regulation of apoptosis signaling involved in anatomical structure development|up regulation of apoptosis signaling involved in development of an anatomical structure|activation of apoptotic programmed cell death involved in anatomical structure development|upregulation of apoptosis activator activity involved in development of an anatomical structure|upregulation of programmed cell death by apoptosis involved in anatomical structure development|positive regulation of apoptotic programmed cell death involved in development of an anatomical structure|up-regulation of apoptotic process involved in development|up-regulation of activation of apoptosis involved in anatomical structure development|up regulation of apoptotic process involved in anatomical structure development|positive regulation of apoptosis involved in development of an anatomical structure|up-regulation of apoptotic cell death involved in anatomical structure development|upregulation of apoptotic cell death involved in anatomical structure development|activation of induction of apoptosis by p53 involved in anatomical structure development|up-regulation of activation of apoptosis involved in development of an anatomical structure|up-regulation of apoptotic process involved in development of an anatomical structure|up-regulation of signaling (initiator) caspase activity involved in anatomical structure development|up regulation of programmed cell death by apoptosis involved in development of an anatomical structure|up regulation of programmed cell death by apoptosis involved in anatomical structure development|activation of commitment to apoptosis involved in development of an anatomical structure|upregulation of programmed cell death by apoptosis involved in development of an anatomical structure|up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure|up-regulation of apoptotic program involved in development of an anatomical structure|activation of activation of apoptosis involved in anatomical structure development|up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure|up-regulation of apoptosis activator activity involved in anatomical structure development|positive regulation of apoptotic program involved in development of an anatomical structure|activation of commitment to apoptosis involved in anatomical structure development|positive regulation of apoptotic process involved in development of an anatomical structure|activation of programmed cell death by apoptosis involved in anatomical structure development|up-regulation of type I programmed cell death involved in development of an anatomical structure|activation of apoptotic cell death involved in anatomical structure development|positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|activation of apoptosis signaling involved in anatomical structure development|up regulation of apoptotic process involved in development of an anatomical structure|activation of induction of apoptosis involved in anatomical structure development|positive regulation of induction of apoptosis involved in development of an anatomical structure|activation of apoptosis signaling involved in development of an anatomical structure|positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure|activation of signaling (initiator) caspase activity involved in anatomical structure development|upregulation of induction of apoptosis by p53 involved in development of an anatomical structure|up regulation of induction of apoptosis by p53 involved in anatomical structure development|up-regulation of apoptosis involved in anatomical structure development				U4PR86 in PMID:22801495 inferred from mutant phenotype		es	2015-10-19T14:12:34Z						biological_process											owl:Class	
GO:0015625	biolink:NamedThing	ABC-type ferric hydroxamate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).	got7fsn_ti	ATPase-coupled ferric-hydroxamate transmembrane transporter activity|ferric-hydroxamate-transporting ATPase activity|ATP-dependent ferric-hydroxamate transmembrane transporter activity|ferric-hydroxamate transmembrane transporter activity|ferric-hydroxamate porter activity|ATP-dependent iron-chelate transporter activity|ATPase-coupled iron-chelate transporter activity|ferric-hydroxamate ABC transporter|iron-chelate-transporting ATPase activity	https://github.com/geneontology/go-ontology/issues/17164									GO:0015409|GO:0102026|GO:0015623|GO:0015622	MetaCyc:3.6.3.34-RXN|MetaCyc:ABC-11-RXN|MetaCyc:ABC-9-RXN|EC:7.2.2.16		molecular_function											owl:Class	
GO:0031952	biolink:NamedThing	regulation of protein autophosphorylation	Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.	got7fsn_ti	regulation of protein amino acid autophosphorylation													biological_process											owl:Class	
GO:1902034	biolink:NamedThing	negative regulation of hematopoietic stem cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation.	got7fsn_ti	negative regulation of hemopoietic stem cell proliferation|down-regulation of hematopoietic stem cell proliferation|inhibition of hematopoietic stem cell proliferation|inhibition of hemopoietic stem cell proliferation|down regulation of hemopoietic stem cell proliferation|down-regulation of hemopoietic stem cell proliferation|downregulation of hematopoietic stem cell proliferation|down regulation of hematopoietic stem cell proliferation|downregulation of hemopoietic stem cell proliferation						ss	2013-04-02T05:13:24Z						biological_process											owl:Class	
GO:2000017	biolink:NamedThing	positive regulation of determination of dorsal identity	Any process that activates or increases the frequency, rate or extent of determination of dorsal identity.	got7fsn_ti	positive regulation of determination of adaxial identity						jl	2010-07-15T03:27:59Z						biological_process											owl:Class	
GO:0001607	biolink:NamedThing	neuromedin U receptor activity	Combining with neuromedin U to initiate a change in cell activity.	got7fsn_ti	NMUR activity													molecular_function											owl:Class	
GO:0009787	biolink:NamedThing	regulation of abscisic acid-activated signaling pathway	Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling.	got7fsn_ti	regulation of abscisic acid mediated signalling|regulation of abscisic acid mediated signaling pathway													biological_process											owl:Class	
GO:0042950	biolink:NamedThing	salicin transmembrane transporter activity	Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042948	biolink:NamedThing	salicin transport	The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0015117	biolink:NamedThing	thiosulfate transmembrane transporter activity	Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other.	got7fsn_ti	thiosulphate transporter activity|thiosulfate permease activity											RHEA:32807		molecular_function											owl:Class	
GO:0002794	biolink:NamedThing	regulation of antimicrobial peptide secretion	Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.	got7fsn_ti														biological_process											owl:Class	
GO:1905271	biolink:NamedThing	regulation of proton-transporting ATP synthase activity, rotational mechanism	Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.	got7fsn_ti	regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|regulation of hydrogen ion transporting two-sector ATPase activity|regulation of H+-transporting ATP synthase activity|regulation of hydrogen ion translocating F-type ATPase activity						als	2016-06-16T12:09:49Z						biological_process											owl:Class	
GO:0060197	biolink:NamedThing	cloacal septation	The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.	got7fsn_ti	cloaca septation													biological_process											owl:Class	
CL:0010009	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009316	biolink:NamedThing	3-isopropylmalate dehydratase complex	A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.	got7fsn_ti	isopropylmalate isomerase complex				See also the molecular function term '3-isopropylmalate dehydratase activity ; GO:0003861'.							MetaCyc:3-ISOPROPYLMALISOM-CPLX		cellular_component											owl:Class	
GO:0046596	biolink:NamedThing	regulation of viral entry into host cell	Any process that modulates the frequency, rate or extent of the viral entry into the host cell.	got7fsn_ti	regulation of viral penetration into host cell|viral escort protein													biological_process											owl:Class	
GO:0039527	biolink:NamedThing	suppression by virus of host TRAF-mediated signal transduction	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of TRAF-mediated signal transduction in the host.	got7fsn_ti	negative regulation by virus of host TRAF-mediated signal transduction|inhibition of host TRAF-mediated signal transduction by virus|suppression by virus of host tumor necrosis factor receptor-associated factor signaling						bf	2011-06-22T05:30:41Z						biological_process											owl:Class	
GO:1905690	biolink:NamedThing	nucleus disassembly	The disaggregation of a nucleus into its constituent components.	got7fsn_ti	cell nucleus disassembly						pr	2016-11-14T13:38:57Z						biological_process											owl:Class	
GO:1900146	biolink:NamedThing	negative regulation of nodal signaling pathway involved in determination of left/right asymmetry	Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.	got7fsn_ti	downregulation of nodal signaling pathway involved in determination of left/right asymmetry|down-regulation of nodal signaling pathway involved in determination of left/right asymmetry|inhibition of nodal signaling pathway involved in determination of left/right asymmetry|negative regulation of nodal signalling pathway involved in determination of left/right asymmetry|down regulation of nodal signaling pathway involved in determination of left/right asymmetry						bf	2012-03-06T11:00:36Z						biological_process											owl:Class	
GO:0045025	biolink:NamedThing	mitochondrial degradosome	A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer.	got7fsn_ti	mtEXO													cellular_component											owl:Class	
CL:0000148	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051461	biolink:NamedThing	positive regulation of corticotropin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.	got7fsn_ti	positive regulation of corticotropic hormone secretion|up-regulation of adrenocorticotropin secretion|upregulation of adrenocorticotropin secretion|positive regulation of adrenocorticotropin secretion|positive regulation of adrenotropin secretion|stimulation of adrenocorticotropin secretion|positive regulation of ACTH secretion|positive regulation of adrenocorticotropic hormone secretion|positive regulation of adrenotropic hormone secretion|activation of adrenocorticotropin secretion|up regulation of adrenocorticotropin secretion													biological_process											owl:Class	
GO:0046807	biolink:NamedThing	viral scaffold assembly and maintenance	The assembly and maintenance of the viral scaffold around which the viral capsid is constructed.	got7fsn_ti					See also the cellular component term 'viral scaffold ; GO:0046806'.									biological_process											owl:Class	
GO:0045472	biolink:NamedThing	response to ether	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0032052	biolink:NamedThing	bile acid binding	Binding to a bile acid, a steroid carboxylic acids occurring in bile.	got7fsn_ti														molecular_function											owl:Class	
GO:0005354	biolink:NamedThing	galactose transmembrane transporter activity	Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.	got7fsn_ti	galactose/glucose (methylgalactoside) porter activity													molecular_function											owl:Class	
GO:0015757	biolink:NamedThing	galactose transmembrane transport	The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.	got7fsn_ti	galactose transport													biological_process											owl:Class	
GO:0070074	biolink:NamedThing	mononeme	A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts.	got7fsn_ti														cellular_component											owl:Class	
GO:0071370	biolink:NamedThing	cellular response to gibberellin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.	got7fsn_ti	cellular response to gibberellic acid stimulus						mah	2009-12-11T03:14:21Z						biological_process											owl:Class	
GO:0021649	biolink:NamedThing	vestibulocochlear nerve structural organization	The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	got7fsn_ti	CN VII structural organization|vestibulocochlear nerve structural organisation													biological_process											owl:Class	
GO:0033601	biolink:NamedThing	positive regulation of mammary gland epithelial cell proliferation	Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.	got7fsn_ti	stimulation of mammary gland epithelial cell proliferation|upregulation of mammary gland epithelial cell proliferation|activation of mammary gland epithelial cell proliferation|up regulation of mammary gland epithelial cell proliferation|up-regulation of mammary gland epithelial cell proliferation													biological_process											owl:Class	
GO:1900272	biolink:NamedThing	negative regulation of long-term synaptic potentiation	Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation.	got7fsn_ti	down regulation of long-term potentiation|down regulation of long-term synaptic potentiation|negative regulation of LTP|inhibition of long-term synaptic potentiation|down-regulation of long-term potentiation|inhibition of long-term potentiation|down regulation of LTP|down-regulation of LTP|negative regulation of long-term potentiation|inhibition of LTP|down-regulation of long-term synaptic potentiation|downregulation of long-term potentiation|downregulation of long-term synaptic potentiation|downregulation of LTP						rl	2012-04-04T07:17:21Z						biological_process											owl:Class	
GO:0002627	biolink:NamedThing	positive regulation of T cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.	got7fsn_ti	stimulation of T cell antigen processing and presentation|positive regulation of T lymphocyte antigen processing and presentation|upregulation of T cell antigen processing and presentation|positive regulation of T-lymphocyte antigen processing and presentation|up regulation of T cell antigen processing and presentation|up-regulation of T cell antigen processing and presentation|positive regulation of T-cell antigen processing and presentation|activation of T cell antigen processing and presentation													biological_process											owl:Class	
GO:1901550	biolink:NamedThing	regulation of endothelial cell development	Any process that modulates the frequency, rate or extent of endothelial cell development.	got7fsn_ti							pr	2012-10-30T12:59:50Z						biological_process											owl:Class	
GO:1905818	biolink:NamedThing	regulation of chromosome separation	Any process that modulates the frequency, rate or extent of chromosome separation.	got7fsn_ti	regulation of rDNA separation|regulation of chromatid release						bhm	2017-01-13T13:55:18Z						biological_process											owl:Class	
GO:1900244	biolink:NamedThing	positive regulation of synaptic vesicle endocytosis	Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.	got7fsn_ti	activation of synaptic vesicle endocytosis|upregulation of synaptic vesicle endocytosis|up-regulation of synaptic vesicle retrieval|positive regulation of synaptic vesicle retrieval|up-regulation of synaptic vesicle endocytosis|upregulation of synaptic vesicle retrieval|up regulation of synaptic vesicle endocytosis|up regulation of synaptic vesicle retrieval|activation of synaptic vesicle retrieval						rl	2012-03-28T01:40:44Z						biological_process											owl:Class	
GO:0003337	biolink:NamedThing	mesenchymal to epithelial transition involved in metanephros morphogenesis	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.	got7fsn_ti	metanephric mesenchyme to epithelial transition						dph	2009-11-24T09:29:49Z						biological_process											owl:Class	
GO:0001731	biolink:NamedThing	formation of translation preinitiation complex	The joining of the small ribosomal subunit, ternary complex, and mRNA.	got7fsn_ti	formation of translation pre-initiation complex|translation preinitiation complex assembly				See also the cellular component terms 'eukaryotic 43S preinitiation complex ; GO:0016282', 'eukaryotic 48S initiation complex ; GO:0033290', and their children.									biological_process											owl:Class	
GO:0071791	biolink:NamedThing	chemokine (C-C motif) ligand 5 binding	Binding to chemokine (C-C motif) ligand 5.	got7fsn_ti	Regulated upon Activation, Normal T-cell Expressed, and Secreted binding|CCL5 binding|RANTES binding						mah	2010-09-01T02:28:22Z						molecular_function											owl:Class	
GO:0015131	biolink:NamedThing	oxaloacetate transmembrane transporter activity	Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:1902356	biolink:NamedThing	oxaloacetate(2-) transmembrane transport	The directed movement of oxaloacetate(2-) across a membrane.	got7fsn_ti							dph	2013-08-14T14:40:37Z						biological_process											owl:Class	
GO:0001621	biolink:NamedThing	G protein-coupled ADP receptor activity	Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	platelet ADP receptor activity|ADP-activated adenosine receptor activity|ADP receptor activity|K101 receptor|ADP-activated nucleotide receptor activity										GO:0045032			molecular_function											owl:Class	
GO:0043531	biolink:NamedThing	ADP binding	Binding to ADP, adenosine 5'-diphosphate.	got7fsn_ti	adenosine 5'-diphosphate binding|adenosine diphosphate binding													molecular_function											owl:Class	
GO:0070235	biolink:NamedThing	regulation of activation-induced cell death of T cells	Any process that modulates the occurrence or rate of activation-induced cell death of T cells.	got7fsn_ti	regulation of activation-induced cell death of T lymphocytes|regulation of activated T cell apoptosis|regulation of activation-induced cell death of T-lymphocytes|regulation of AICD|regulation of activation-induced cell death of T-cells|regulation of antigen-driven apoptosis													biological_process											owl:Class	
GO:0042673	biolink:NamedThing	regulation of retinal cone cell fate specification	Any process that mediates the specification of a cell into a retinal cone cell.	got7fsn_ti														biological_process											owl:Class	
GO:0022898	biolink:NamedThing	regulation of transmembrane transporter activity	Any process that modulates the frequency, rate or extent of transmembrane transporter activity.	got7fsn_ti														biological_process											owl:Class	
GO:1902962	biolink:NamedThing	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.	got7fsn_ti	regulation of metalloendoprotease activity involved in APP catabolism|regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|regulation of metalloendoproteinase activity involved in APP catabolism|regulation of metalloendoprotease activity involved in APP catabolic process|regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|regulation of metalloendopeptidase activity involved in APP catabolism|regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|regulation of metalloendoproteinase activity involved in APP catabolic process|regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|regulation of metalloendopeptidase activity involved in APP catabolic process						sjp	2014-05-06T09:11:55Z						biological_process											owl:Class	
GO:0097166	biolink:NamedThing	lens epithelial cell proliferation	The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.	got7fsn_ti							pr	2011-09-29T01:27:50Z						biological_process											owl:Class	
GO:1903473	biolink:NamedThing	positive regulation of mitotic actomyosin contractile ring contraction	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction.	got7fsn_ti	activation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|up-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|positive regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|activation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|positive regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of mitotic actomyosin contractile ring contraction|upregulation of mitotic actomyosin contractile ring contraction|up regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|up-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of mitotic actomyosin contractile ring contraction|up regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of mitotic actomyosin contractile ring constriction|up regulation of mitotic actomyosin contractile ring contraction|upregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/21855					vw	2014-09-23T14:10:46Z						biological_process											owl:Class	
GO:0098853	biolink:NamedThing	endoplasmic reticulum-vacuole membrane contact site	A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes.	got7fsn_ti	ER-vacuole membrane contact site|endoplasmic reticulum-vacuole membrane contact site													cellular_component											owl:Class	
GO:0106089	biolink:NamedThing	negative regulation of cell adhesion involved in sprouting angiogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.	got7fsn_ti							hjd	2018-01-22T18:28:08Z						biological_process											owl:Class	
GO:0015530	biolink:NamedThing	shikimate transmembrane transporter activity	Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.	got7fsn_ti														molecular_function											owl:Class	
GO:0015733	biolink:NamedThing	shikimate transmembrane transport	The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	shikimate transport													biological_process											owl:Class	
PO:0009074	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061179	biolink:NamedThing	negative regulation of insulin secretion involved in cellular response to glucose stimulus	Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.	got7fsn_ti	negative regulation of insulin secretion in response to glucose|negative regulation of insulin secretion involved in cellular response to glucose						dph	2010-07-13T09:41:46Z						biological_process											owl:Class	
GO:0005458	biolink:NamedThing	GDP-mannose transmembrane transporter activity	Enables the transfer of a GDP-mannose from one side of a membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:1990570	biolink:NamedThing	GDP-mannose transmembrane transport	The process in which GDP-mannose is transported across a membrane.	got7fsn_ti	GDP-mannose transport						vw	2014-11-27T12:05:09Z			GO:0015784			biological_process											owl:Class	
GO:0010058	biolink:NamedThing	regulation of atrichoblast fate specification	Any process that modulates atrichoblast fate specification.	got7fsn_ti														biological_process											owl:Class	
GO:0003190	biolink:NamedThing	atrioventricular valve formation	The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	got7fsn_ti	AV valve formation						dph	2009-10-08T01:07:28Z						biological_process											owl:Class	
GO:1902908	biolink:NamedThing	regulation of melanosome transport	Any process that modulates the frequency, rate or extent of melanosome transport.	got7fsn_ti							als	2014-04-17T11:40:16Z						biological_process											owl:Class	
GO:0032253	biolink:NamedThing	dense core granule localization	Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	dense core granule clustering|dense core vesicle localization|dense core granule localisation													biological_process											owl:Class	
GO:0060047	biolink:NamedThing	heart contraction	The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.	got7fsn_ti	cardiac contraction|hemolymph circulation|heart beating													biological_process											owl:Class	
GO:0002353	biolink:NamedThing	plasma kallikrein-kinin cascade	A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.	got7fsn_ti														biological_process											owl:Class	
GO:0035619	biolink:NamedThing	root hair tip	The tip portion of an outgrowth of a root epidermal cell.	got7fsn_ti	root hair cell tip						bf	2010-12-03T01:43:55Z						cellular_component											owl:Class	
GO:1905294	biolink:NamedThing	positive regulation of neural crest cell differentiation	Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation.	got7fsn_ti	up regulation of neural crest cell differentiation|upregulation of neural crest cell differentiation|activation of neural crest cell differentiation|up-regulation of neural crest cell differentiation						rl	2016-06-28T15:02:16Z						biological_process											owl:Class	
GO:0042656	biolink:NamedThing	JUN kinase kinase kinase kinase activity	Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs).	got7fsn_ti	JUNKKKK activity													molecular_function											owl:Class	
GO:0072349	biolink:NamedThing	modified amino acid transmembrane transporter activity	Enables the transfer of modified amino acids from one side of a membrane to the other.	got7fsn_ti	amino acid derivative transmembrane transporter activity|modified amino acid transporter activity						mah	2010-11-11T11:50:31Z						molecular_function											owl:Class	
GO:0072337	biolink:NamedThing	modified amino acid transport	The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	amino acid derivative transport						mah	2010-11-04T12:18:23Z						biological_process											owl:Class	
GO:1900486	biolink:NamedThing	positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.	got7fsn_ti	activation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|activation of isopentenyl diphosphate anabolism, mevalonate pathway|upregulation of acetate-mevalonate pathway|activation of acetate-mevalonate pathway|up regulation of Ac-MVA pathway|positive regulation of isopentenyl diphosphate synthesis, mevalonate pathway|positive regulation of isopentenyl diphosphate anabolism, mevalonate pathway|upregulation of isopentenyl diphosphate synthesis, mevalonate pathway|up-regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up-regulation of acetate-mevalonate pathway|activation of isopentenyl diphosphate synthesis, mevalonate pathway|up-regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|upregulation of isopentenyl diphosphate anabolism, mevalonate pathway|positive regulation of isopentenyl diphosphate formation, mevalonate pathway|up regulation of isopentenyl diphosphate formation, mevalonate pathway|up-regulation of isopentenyl diphosphate anabolism, mevalonate pathway|activation of Ac-MVA pathway|up regulation of isopentenyl diphosphate synthesis, mevalonate pathway|upregulation of isopentenyl diphosphate formation, mevalonate pathway|activation of isopentenyl diphosphate formation, mevalonate pathway|positive regulation of acetate-mevalonate pathway|up regulation of acetate-mevalonate pathway|up regulation of isopentenyl diphosphate anabolism, mevalonate pathway|upregulation of Ac-MVA pathway|upregulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|up-regulation of Ac-MVA pathway|positive regulation of Ac-MVA pathway|up regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|up-regulation of isopentenyl diphosphate formation, mevalonate pathway						al	2012-05-02T10:46:46Z						biological_process											owl:Class	
GO:0097590	biolink:NamedThing	archaeal-type flagellum-dependent cell motility	Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel.	got7fsn_ti	archaeal-type flagellar cell motility						pr	2014-03-25T20:40:50Z						biological_process											owl:Class	
GO:0031954	biolink:NamedThing	positive regulation of protein autophosphorylation	Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.	got7fsn_ti	positive regulation of protein amino acid autophosphorylation|stimulation of protein amino acid autophosphorylation|upregulation of protein amino acid autophosphorylation|activation of protein amino acid autophosphorylation|up regulation of protein amino acid autophosphorylation|up-regulation of protein amino acid autophosphorylation													biological_process											owl:Class	
GO:1903397	biolink:NamedThing	positive regulation of secondary cell septum biogenesis	Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis.	got7fsn_ti	up regulation of secondary cell septum biogenesis|up-regulation of secondary cell septum biogenesis|upregulation of secondary cell septum biogenesis|activation of secondary cell septum biogenesis						di	2014-08-29T21:42:34Z						biological_process											owl:Class	
GO:0120200	biolink:NamedThing	rod photoreceptor outer segment	The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins.	got7fsn_ti							krc	2019-05-07T22:47:20Z						cellular_component											owl:Class	
GO:2000480	biolink:NamedThing	negative regulation of cAMP-dependent protein kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.	got7fsn_ti	negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|negative regulation of AMPK|negative regulation of protein kinase A activity|negative regulation of PKA C|negative regulation of cyclic AMP-dependent protein kinase activity|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|negative regulation of STK22|negative regulation of 3',5'-cAMP-dependent protein kinase activity|negative regulation of PKA|negative regulation of 3',5' cAMP-dependent protein kinase activity|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity						yaf	2011-03-10T11:13:45Z						biological_process											owl:Class	
GO:0042314	biolink:NamedThing	bacteriochlorophyll binding	Binding to bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants.	got7fsn_ti														molecular_function											owl:Class	
GO:1904324	biolink:NamedThing	negative regulation of inhibitory G protein-coupled receptor phosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.	got7fsn_ti	negative regulation of inhibitory G-protein coupled receptor phosphorylation|down regulation of inhibitory G-protein coupled receptor phosphorylation|inhibition of inhibitory G-protein coupled receptor phosphorylation|downregulation of inhibitory G-protein coupled receptor phosphorylation|down-regulation of inhibitory G-protein coupled receptor phosphorylation						sl	2015-06-10T19:46:43Z						biological_process											owl:Class	
GO:0042947	biolink:NamedThing	glucoside transmembrane transporter activity	Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue.	got7fsn_ti														molecular_function											owl:Class	
GO:0042946	biolink:NamedThing	glucoside transport	The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue.	got7fsn_ti														biological_process											owl:Class	
GO:0005851	biolink:NamedThing	eukaryotic translation initiation factor 2B complex	A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.	got7fsn_ti	eIF-2B|eif2B													cellular_component											owl:Class	
GO:1990573	biolink:NamedThing	potassium ion import across plasma membrane	The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	potassium import|potassium ion uptake|potassium ion import						vw	2014-12-04T09:48:12Z			GO:0010107			biological_process											owl:Class	
GO:0001676	biolink:NamedThing	long-chain fatty acid metabolic process	The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain fatty acid metabolism													biological_process											owl:Class	
GO:0010922	biolink:NamedThing	positive regulation of phosphatase activity	Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0044166	biolink:NamedThing	host cell endoplasmic reticulum lumen	The volume enclosed by the membranes of the host cell endoplasmic reticulum.	got7fsn_ti	host endoplasmic reticulum lumen						jl	2009-09-04T11:13:30Z						cellular_component											owl:Class	
GO:0062177	biolink:NamedThing	radial spoke assembly	The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules.	got7fsn_ti							dph	2019-11-20T17:50:08Z						biological_process											owl:Class	
GO:0005274	biolink:NamedThing	allantoin:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport.	got7fsn_ti	allantoin uptake transmembrane transporter activity|allantoin/allantoate transporter|allantoin permease activity										GO:0015206			molecular_function											owl:Class	
GO:0015720	biolink:NamedThing	allantoin transport	The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	allantoin/allantoate transport|allantoin transmembrane transport													biological_process											owl:Class	
GO:0003333	biolink:NamedThing	amino acid transmembrane transport	The process in which an amino acid is transported across a membrane.	got7fsn_ti	amino acid membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		dph	2009-11-02T02:36:11Z						biological_process											owl:Class	
GO:0001536	biolink:NamedThing	radial spoke stalk	Globular portion of the radial spoke that projects towards the central pair of microtubules.	got7fsn_ti														cellular_component											owl:Class	
GO:1902981	biolink:NamedThing	synthesis of RNA primer involved in mitotic DNA replication	Any synthesis of RNA primer involved in mitotic cell cycle DNA replication.	got7fsn_ti	synthesis of RNA primer involved in mitotic cell cycle DNA replication						jl	2014-05-06T19:20:00Z			GO:1903458			biological_process											owl:Class	
GO:1902557	biolink:NamedThing	5'-adenylyl sulfate transmembrane transporter activity	Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other.	got7fsn_ti					An example of this is the YPR011C gene product in S. cerevisiae in PMID:24296033.		mcc	2013-12-09T23:08:05Z						molecular_function											owl:Class	
GO:1902558	biolink:NamedThing	5'-adenylyl sulfate transmembrane transport	The process in which 5'-adenylyl sulfate is transported across a membrane.	got7fsn_ti	adenosine 5'-phosphosulfate transmembrane transport						mcc	2013-12-09T23:16:01Z						biological_process											owl:Class	
GO:0019977	biolink:NamedThing	interleukin-21 binding	Binding to interleukin-21.	got7fsn_ti	IL-21 binding													molecular_function											owl:Class	
GO:1901397	biolink:NamedThing	positive regulation of transforming growth factor beta2 activation	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation.	got7fsn_ti	upregulation of TGFB2 activation|positive regulation of TGF-beta 2 activation|up regulation of TGFB2 activation|up-regulation of TGFbeta 2 activation|activation of transforming growth factor beta2 activation|positive regulation of TGFB2 activation|up regulation of transforming growth factor beta2 activation|up regulation of TGFbeta 2 activation|upregulation of transforming growth factor beta2 activation|positive regulation of TGFbeta 2 activation|up regulation of TGF-beta 2 activation|up-regulation of transforming growth factor beta2 activation|upregulation of TGF-beta 2 activation|upregulation of TGFbeta 2 activation|activation of TGF-beta 2 activation|up-regulation of TGFB2 activation|up-regulation of TGF-beta 2 activation|activation of TGFbeta 2 activation|activation of TGFB2 activation						bf	2012-10-01T10:48:15Z						biological_process											owl:Class	
GO:0034089	biolink:NamedThing	establishment of meiotic sister chromatid cohesion	The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0070129	biolink:NamedThing	regulation of mitochondrial translation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.	got7fsn_ti	regulation of mitochondrial protein synthesis|regulation of mitochondrial protein formation|regulation of mitochondrial protein biosynthesis|regulation of mitochondrial protein anabolism													biological_process											owl:Class	
GO:0010522	biolink:NamedThing	regulation of calcium ion transport into cytosol	Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.	got7fsn_ti														biological_process											owl:Class	
GO:0002809	biolink:NamedThing	negative regulation of antibacterial peptide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis.	got7fsn_ti	down-regulation of antibacterial peptide biosynthetic process|downregulation of antibacterial peptide biosynthetic process|inhibition of antibacterial peptide biosynthetic process|down regulation of antibacterial peptide biosynthetic process													biological_process											owl:Class	
GO:0045069	biolink:NamedThing	regulation of viral genome replication	Any process that modulates the frequency, rate or extent of viral genome replication.	got7fsn_ti														biological_process											owl:Class	
GO:1905447	biolink:NamedThing	negative regulation of mitochondrial ATP synthesis coupled electron transport	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.	got7fsn_ti	inhibition of mitochondrial ATP synthesis coupled electron transport|downregulation of mitochondrial ATP synthesis coupled electron transport|down regulation of mitochondrial ATP synthesis coupled electron transport|down-regulation of mitochondrial ATP synthesis coupled electron transport						dph	2016-09-15T18:58:06Z						biological_process											owl:Class	
GO:0010809	biolink:NamedThing	negative regulation of synaptic vesicle priming	Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0000918	biolink:NamedThing	division septum site selection	The process of marking the site where a division septum will form.	got7fsn_ti	septin assembly and septum biosynthesis|septin assembly and septum formation|septum positioning|selection of site for division septum formation|selection of site for barrier cell septum biosynthesis|selection of site for barrier cell septum formation													biological_process											owl:Class	
GO:0060506	biolink:NamedThing	smoothened signaling pathway involved in lung development	The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.	got7fsn_ti	hh signaling pathway involved in lung development|hedgehog signaling pathway involved in lung development|smoothened signalling pathway involved in lung development													biological_process											owl:Class	
GO:0048209	biolink:NamedThing	regulation of vesicle targeting, to, from or within Golgi	Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.	got7fsn_ti	regulation of Golgi vesicle targeting													biological_process											owl:Class	
GO:0043709	biolink:NamedThing	cell adhesion involved in single-species biofilm formation	The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.	got7fsn_ti	cell adhesion during single-species biofilm formation													biological_process											owl:Class	
GO:0003216	biolink:NamedThing	cardiac left atrium formation	The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts.	got7fsn_ti							dph	2009-10-13T09:52:31Z						biological_process											owl:Class	
GO:0003212	biolink:NamedThing	cardiac left atrium morphogenesis	The process in which the left cardiac atrium is generated and organized.	got7fsn_ti							dph	2009-10-13T09:48:16Z						biological_process											owl:Class	
GO:0034986	biolink:NamedThing	iron chaperone activity	Directly binding to and delivering iron ions to a target protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0005506	biolink:NamedThing	iron ion binding	Binding to an iron (Fe) ion.	got7fsn_ti	iron binding													molecular_function											owl:Class	
GO:1904456	biolink:NamedThing	negative regulation of neuronal action potential	Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.	got7fsn_ti	down-regulation of neuronal action potential|downregulation of neuronal action potential|negative regulation of generation of action potential|inhibition of neuronal action potential|down regulation of generation of action potential|inhibition of generation of action potential|downregulation of generation of action potential|down-regulation of generation of action potential|down regulation of neuronal action potential						sl	2015-07-09T18:02:40Z						biological_process											owl:Class	
GO:0030510	biolink:NamedThing	regulation of BMP signaling pathway	Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.	got7fsn_ti	regulation of BMP receptor signaling pathway|regulation of bone morphogenetic protein signaling pathway|regulation of BMP signalling pathway|regulation of decapentaplegic receptor signaling pathway|regulation of bone morphogenetic protein signalling pathway|regulation of decapentaplegic signaling pathway|regulation of decapentaplegic receptor signalling pathway						tb	2009-11-13T10:49:14Z			GO:0090097			biological_process											owl:Class	
GO:0031096	biolink:NamedThing	platelet dense tubular network lumen	The volume enclosed by the membranes of the platelet dense tubular network.	got7fsn_ti														cellular_component											owl:Class	
GO:2000730	biolink:NamedThing	regulation of termination of RNA polymerase I transcription	Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription.	got7fsn_ti	regulation of transcription termination from RNA polymerase I promoter|regulation of RNA polymerase I transcription termination|regulation of transcription termination from Pol I promoter						dph	2011-06-10T08:43:39Z						biological_process											owl:Class	
GO:0061511	biolink:NamedThing	centriole elongation	The centrosome organization process by which a centriole increases in length as part of the process of replication.	got7fsn_ti							dph	2013-03-22T09:06:27Z						biological_process											owl:Class	
GO:0003372	biolink:NamedThing	establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell.	got7fsn_ti							dph	2009-12-08T05:46:23Z						biological_process											owl:Class	
GO:0003369	biolink:NamedThing	establishment of cell polarity involved in mesendodermal cell migration	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell.	got7fsn_ti							dph	2009-12-08T05:31:51Z						biological_process											owl:Class	
GO:0001761	biolink:NamedThing	beta-alanine transmembrane transporter activity	Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.	got7fsn_ti	beta-alanine transporter activity													molecular_function											owl:Class	
GO:0099108	biolink:NamedThing	potassium channel activator activity involved in G protein-coupled receptor signaling pathway	Activation potassium ion channel activity via direct interaction with a potassium ion channel during G protein-coupled receptor signaling.	got7fsn_ti	potassium channel activator activity involved in G-protein coupled receptor signaling pathway				Examples include G-protein beta-gamma complexes that bind to and activate potassium channels.									molecular_function											owl:Class	
GO:0099109	biolink:NamedThing	potassium channel activating, G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel.	got7fsn_ti	potassium channel activating, G-protein coupled receptor signaling pathway													biological_process											owl:Class	
GO:0031147	biolink:NamedThing	1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process	The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.	got7fsn_ti	1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolism|DIF-1 metabolic process|DIF-1 metabolism													biological_process											owl:Class	
GO:1902760	biolink:NamedThing	Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide.	got7fsn_ti	Mo(VI)-molybdopterin cytosine dinucleotide biosynthesis|Mo(VI)-molybdopterin cytosine dinucleotide anabolism|Mo(VI)-molybdopterin cytosine dinucleotide formation|Mo(VI)-molybdopterin cytosine dinucleotide synthesis|Mo-molybdopterin-cytosine-dinucleotide cofactor biosynthetic process						dph	2014-03-06T14:00:43Z			GO:0061601	MetaCyc:PWY-6476		biological_process											owl:Class	
GO:0042911	biolink:NamedThing	acridine transmembrane transporter activity	Enables the directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene from one side of a membrane to the other.	got7fsn_ti	acridine transporter activity													molecular_function											owl:Class	
GO:0042909	biolink:NamedThing	acridine transport	The directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1905284	biolink:NamedThing	positive regulation of epidermal growth factor receptor signaling pathway involved in heart process	Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.	got7fsn_ti	upregulation of EGF receptor signaling pathway involved in heart process|up-regulation of EGF receptor signaling pathway involved in heart process|up regulation of EGF receptor signalling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of EGF receptor signaling pathway involved in heart process|up regulation of EGF receptor signalling pathway involved in cardiac process|upregulation of ERBB1 signaling pathway involved in cardiac process|up-regulation of ERBB1 signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in heart process|positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of ERBB1 signaling pathway involved in cardiac process|upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in cardiac process|activation of EGF receptor signalling pathway involved in cardiac process|upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|positive regulation of EGF receptor signaling pathway involved in cardiac process|activation of EGFR signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in cardiac process|activation of ERBB1 signaling pathway involved in cardiac process|up-regulation of ERBB1 signaling pathway involved in heart process|activation of epidermal growth factor receptor signalling pathway involved in heart process|activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up-regulation of EGF receptor signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signalling pathway involved in heart process|up regulation of ERBB1 signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signalling pathway involved in heart process|up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of epidermal growth factor receptor signalling pathway involved in heart process|up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|up-regulation of EGF receptor signalling pathway involved in heart process|upregulation of epidermal growth factor receptor signalling pathway involved in heart process|up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|upregulation of EGF receptor signalling pathway involved in heart process|upregulation of ERBB1 signaling pathway involved in heart process|activation of ERBB1 signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of EGFR signaling pathway involved in heart process|upregulation of EGF receptor signaling pathway involved in cardiac process|activation of EGF receptor signalling pathway involved in heart process|upregulation of EGF receptor signalling pathway involved in cardiac process|positive regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|upregulation of EGFR signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|activation of EGFR signaling pathway involved in heart process|up-regulation of EGFR signaling pathway involved in heart process|upregulation of EGFR signaling pathway involved in heart process|activation of epidermal growth factor receptor signaling pathway involved in heart process|up-regulation of EGF receptor signalling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in heart process|activation of EGF receptor signaling pathway involved in cardiac process|positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up regulation of ERBB1 signaling pathway involved in heart process|up-regulation of EGFR signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up regulation of EGFR signaling pathway involved in cardiac process|up regulation of EGF receptor signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signaling pathway involved in heart process|positive regulation of ERBB1 signaling pathway involved in heart process|activation of EGF receptor signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signalling pathway involved in cardiac process|activation of epidermal growth factor receptor signalling pathway involved in cardiac process						bc	2016-06-20T14:40:57Z						biological_process											owl:Class	
GO:0070130	biolink:NamedThing	negative regulation of mitochondrial translation	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.	got7fsn_ti	negative regulation of mitochondrial protein synthesis|negative regulation of mitochondrial protein biosynthesis|negative regulation of mitochondrial protein anabolism|negative regulation of mitochondrial protein formation													biological_process											owl:Class	
GO:0110160	biolink:NamedThing	negative regulation of mitotic spindle formation (spindle phase one)	Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).	got7fsn_ti							kmv	2019-08-12T15:18:32Z						biological_process											owl:Class	
GO:0046610	biolink:NamedThing	lysosomal proton-transporting V-type ATPase, V0 domain	The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.	got7fsn_ti	lysosomal hydrogen ion-transporting ATPase V0 domain													cellular_component											owl:Class	
GO:0061763	biolink:NamedThing	multivesicular body-lysosome fusion	The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.	got7fsn_ti	MVB-lysosome fusion|fusion of MVB to lysosome|fusion of multivesicular body to lysosome						dph	2016-04-15T07:12:40Z						biological_process											owl:Class	
GO:0005946	biolink:NamedThing	alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present.	got7fsn_ti	UDP-glucose-glucosephosphate glucosyltransferase complex|trehalose-6-phosphate synthase/phosphatase|trehalose-6-phosphate synthase complex				See also the molecular function term 'alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity ; GO:0003825'.									cellular_component											owl:Class	
GO:2000236	biolink:NamedThing	negative regulation of tRNA processing	Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.	got7fsn_ti	negative regulation of tRNA maturation						mah	2010-11-10T12:15:13Z						biological_process											owl:Class	
GO:1904343	biolink:NamedThing	positive regulation of colon smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction.	got7fsn_ti	activation of colon smooth muscle contraction|up-regulation of colon smooth muscle contraction|upregulation of colon smooth muscle contraction|up regulation of colon smooth muscle contraction						sl	2015-06-11T21:17:11Z						biological_process											owl:Class	
GO:0006094	biolink:NamedThing	gluconeogenesis	The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.	got7fsn_ti	glucose biosynthetic process|glucose biosynthesis											Wikipedia:Gluconeogenesis|MetaCyc:GLUCONEO-PWY		biological_process											owl:Class	
GO:0000332	biolink:NamedThing	template for synthesis of G-rich strand of telomere DNA activity	Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA.	got7fsn_ti	telomerase RNA|telomerase, template				Note that this term describes the activity of an RNA gene product that interacts with other nucleic acid molecules via base pairing; it should not be used to annotate proteins.									molecular_function											owl:Class	
GO:0062123	biolink:NamedThing	regulation of linear element maturation	Any process that modulates the rate, frequency or extent of linear element maturation.	got7fsn_ti							dph	2019-04-23T13:36:20Z						biological_process											owl:Class	
GO:0051034	biolink:NamedThing	tRNA transmembrane transporter activity	Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:1902188	biolink:NamedThing	positive regulation of viral release from host cell	Any process that activates or increases the frequency, rate or extent of viral release from host cell.	got7fsn_ti	up-regulation of viral shedding|positive regulation of release of virus from host|up-regulation of viral release|upregulation of viral release|positive regulation of viral release|up regulation of viral shedding|activation of viral exit|up regulation of viral release from host cell|positive regulation of viral exit|up-regulation of release of virus from host|upregulation of release of virus from host|up-regulation of viral exit|upregulation of viral shedding|activation of viral shedding|upregulation of viral exit|up regulation of viral exit|up-regulation of viral release from host cell|activation of viral release|activation of viral release from host cell|upregulation of viral release from host cell|activation of release of virus from host|positive regulation of viral shedding|up regulation of release of virus from host|up regulation of viral release						ss	2013-06-04T03:54:14Z						biological_process											owl:Class	
GO:1900263	biolink:NamedThing	negative regulation of DNA-directed DNA polymerase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity.	got7fsn_ti	downregulation of epsilon DNA polymerase activity|down-regulation of Klenow fragment|inhibition of sequenase|down regulation of DNA polymerase alpha|down regulation of Taq Pol I|down regulation of deoxyribonucleic duplicase activity|down regulation of DNA-dependent DNA polymerase activity|down regulation of zeta DNA polymerase activity|down regulation of epsilon DNA polymerase activity|down regulation of DNA polymerase beta|down regulation of DNA polymerase gamma|inhibition of DNA polymerase II|inhibition of DNA-dependent DNA polymerase activity|negative regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|down regulation of mu DNA polymerase activity|downregulation of beta DNA polymerase activity|negative regulation of DNA polymerase gamma|down-regulation of Tca DNA polymerase|down-regulation of theta DNA polymerase activity|inhibition of alpha DNA polymerase activity|down-regulation of sigma DNA polymerase activity|negative regulation of epsilon DNA polymerase activity|down regulation of DNA nucleotidyltransferase (DNA-directed) activity|down-regulation of DNA-directed DNA polymerase activity|downregulation of eta DNA polymerase activity|negative regulation of deoxyribonucleic polymerase I|down-regulation of alpha DNA polymerase activity|down-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of epsilon DNA polymerase activity|inhibition of DNA polymerase I|negative regulation of sequenase|negative regulation of beta DNA polymerase activity|downregulation of sequenase|down-regulation of DNA-dependent DNA polymerase activity|down-regulation of DNA polymerase III|inhibition of delta DNA polymerase activity|negative regulation of DNA polymerase II|downregulation of DNA polymerase gamma|inhibition of deoxyribonucleic polymerase I|downregulation of mu DNA polymerase activity|negative regulation of DNA polymerase alpha|downregulation of Tca DNA polymerase|negative regulation of mu DNA polymerase activity|inhibition of nu DNA polymerase activity|inhibition of sigma DNA polymerase activity|downregulation of kappa DNA polymerase activity|down regulation of DNA replicase activity|negative regulation of theta DNA polymerase activity|inhibition of DNA polymerase V activity|downregulation of deoxyribonucleic polymerase I|down-regulation of lambda DNA polymerase activity|downregulation of theta DNA polymerase activity|down-regulation of gamma DNA-directed DNA polymerase activity|inhibition of gamma DNA-directed DNA polymerase activity|down regulation of lambda DNA polymerase activity|downregulation of DNA replicase activity|inhibition of Tca DNA polymerase|negative regulation of lambda DNA polymerase activity|down-regulation of DNA polymerase I|downregulation of DNA polymerase beta|inhibition of mu DNA polymerase activity|inhibition of DNA-directed DNA polymerase activity|negative regulation of eta DNA polymerase activity|down-regulation of DNA polymerase alpha|downregulation of zeta DNA polymerase activity|downregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of Taq Pol I|inhibition of deoxyribonucleic acid duplicase activity|down-regulation of iota DNA polymerase activity|down regulation of theta DNA polymerase activity|down regulation of delta DNA polymerase activity|down regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of duplicase|negative regulation of DNA polymerase beta|inhibition of eta DNA polymerase activity|down-regulation of Taq DNA polymerase|downregulation of deoxyribonucleic acid duplicase activity|down regulation of DNA polymerase V activity|negative regulation of DNA-dependent DNA polymerase activity|negative regulation of duplicase|inhibition of DNA nucleotidyltransferase (DNA-directed) activity|negative regulation of Tca DNA polymerase|inhibition of theta DNA polymerase activity|negative regulation of DNA polymerase III|down regulation of DNA polymerase II|down-regulation of DNA duplicase activity|down regulation of duplicase|down-regulation of DNA polymerase gamma|downregulation of sigma DNA polymerase activity|down regulation of DNA-directed DNA polymerase activity|negative regulation of DNA replicase activity|downregulation of alpha DNA polymerase activity|negative regulation of deoxyribonucleic duplicase activity|down regulation of gamma DNA-directed DNA polymerase activity|negative regulation of alpha DNA polymerase activity|negative regulation of delta DNA polymerase activity|downregulation of Klenow fragment|down-regulation of deoxyribonucleic duplicase activity|downregulation of DNA polymerase II|down-regulation of DNA polymerase V activity|inhibition of DNA polymerase alpha|down-regulation of delta DNA polymerase activity|down regulation of nu DNA polymerase activity|inhibition of kappa DNA polymerase activity|inhibition of DNA duplicase activity|negative regulation of DNA nucleotidyltransferase (DNA-directed) activity|down-regulation of epsilon DNA polymerase activity|negative regulation of sigma DNA polymerase activity|down regulation of DNA polymerase I|down regulation of DNA duplicase activity|inhibition of iota DNA polymerase activity|downregulation of lambda DNA polymerase activity|inhibition of lambda DNA polymerase activity|downregulation of duplicase|down regulation of Klenow fragment|inhibition of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|down-regulation of zeta DNA polymerase activity|downregulation of DNA-directed DNA polymerase activity|downregulation of DNA nucleotidyltransferase (DNA-directed) activity|negative regulation of kappa DNA polymerase activity|negative regulation of Taq DNA polymerase|inhibition of Klenow fragment|negative regulation of DNA polymerase I|negative regulation of DNA polymerase V activity|down regulation of deoxyribonucleic polymerase I|down regulation of Taq DNA polymerase|down regulation of beta DNA polymerase activity|down-regulation of duplicase|inhibition of DNA polymerase gamma|inhibition of DNA polymerase III|downregulation of nu DNA polymerase activity|downregulation of DNA polymerase V activity|downregulation of delta DNA polymerase activity|down-regulation of DNA replicase activity|downregulation of gamma DNA-directed DNA polymerase activity|down regulation of sequenase|down-regulation of eta DNA polymerase activity|down-regulation of Taq Pol I|down-regulation of kappa DNA polymerase activity|down regulation of iota DNA polymerase activity|inhibition of Taq DNA polymerase|down-regulation of deoxyribonucleic acid duplicase activity|down-regulation of mu DNA polymerase activity|down regulation of kappa DNA polymerase activity|negative regulation of gamma DNA-directed DNA polymerase activity|downregulation of Taq DNA polymerase|down-regulation of DNA polymerase beta|inhibition of DNA replicase activity|negative regulation of DNA duplicase activity|inhibition of DNA polymerase beta|downregulation of DNA polymerase I|downregulation of DNA duplicase activity|downregulation of iota DNA polymerase activity|down regulation of deoxyribonucleic acid duplicase activity|down-regulation of DNA polymerase II|negative regulation of iota DNA polymerase activity|down regulation of Tca DNA polymerase|downregulation of DNA polymerase III|down regulation of alpha DNA polymerase activity|downregulation of DNA-dependent DNA polymerase activity|downregulation of Taq Pol I|negative regulation of Klenow fragment|negative regulation of Taq Pol I|down regulation of sigma DNA polymerase activity|inhibition of zeta DNA polymerase activity|down-regulation of DNA nucleotidyltransferase (DNA-directed) activity|negative regulation of zeta DNA polymerase activity|inhibition of beta DNA polymerase activity|down regulation of DNA polymerase III|negative regulation of nu DNA polymerase activity|down regulation of eta DNA polymerase activity|negative regulation of deoxyribonucleic acid duplicase activity|downregulation of DNA polymerase alpha|downregulation of deoxyribonucleic duplicase activity|inhibition of deoxyribonucleic duplicase activity|down-regulation of beta DNA polymerase activity|down-regulation of sequenase|down-regulation of nu DNA polymerase activity|down-regulation of deoxyribonucleic polymerase I						tb	2012-04-03T11:07:18Z						biological_process											owl:Class	
GO:1900103	biolink:NamedThing	positive regulation of endoplasmic reticulum unfolded protein response	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response.	got7fsn_ti	upregulation of endoplasmic reticulum unfolded protein response|up regulation of SREBP-mediated signalling pathway|up-regulation of endoplasmic reticulum unfolded protein response|up-regulation of SREBP-mediated signalling pathway|up-regulation of erUPR|upregulation of SREBP-mediated signalling pathway|positive regulation of SREBP-mediated signalling pathway|up regulation of endoplasmic reticulum unfolded protein response|positive regulation of erUPR|upregulation of ER unfolded protein response|activation of ER unfolded protein response|positive regulation of ER unfolded protein response|up-regulation of ER unfolded protein response|activation of endoplasmic reticulum unfolded protein response|activation of erUPR|up regulation of erUPR|activation of SREBP-mediated signalling pathway|upregulation of erUPR|up regulation of ER unfolded protein response						ppm	2012-02-15T11:15:35Z						biological_process											owl:Class	
GO:1905685	biolink:NamedThing	negative regulation of plasma membrane repair	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair.	got7fsn_ti	inhibition of plasma membrane repair|down-regulation of plasma membrane repair|down regulation of plasma membrane repair|downregulation of plasma membrane repair						bhm	2016-11-14T10:30:38Z						biological_process											owl:Class	
GO:0001217	biolink:NamedThing	DNA-binding transcription repressor activity	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.	got7fsn_ti	bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase transcriptional repressor activity, copper ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|bacterial-type RNA polymerase transcriptional repressor activity, cadmium ion regulated sequence-specific DNA binding|bacterial-type DNA binding transcription repressor activity|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase transcriptional repressor activity, metal ion regulated sequence-specific DNA binding|copper ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|cadmium ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription	https://github.com/geneontology/go-ontology/issues/16736|https://github.com/geneontology/go-ontology/issues/20253			For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2011-01-26T03:15:45Z			GO:0001141|GO:0001218|GO:0001220|GO:0001219			molecular_function											owl:Class	
GO:0060350	biolink:NamedThing	endochondral bone morphogenesis	The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.	got7fsn_ti														biological_process											owl:Class	
GO:0042958	biolink:NamedThing	maltodextrin transmembrane transporter activity	Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042956	biolink:NamedThing	maltodextrin transport	The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:2000314	biolink:NamedThing	negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.	got7fsn_ti	negative regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation						vk	2011-01-18T10:26:56Z						biological_process											owl:Class	
GO:0015742	biolink:NamedThing	alpha-ketoglutarate transport	The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	mitochondrial alpha-ketoglutarate/malate transport|2-oxoglutarate transport													biological_process											owl:Class	
GO:0001580	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of bitter taste	The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.	got7fsn_ti	sensory transduction of bitter taste|perception of bitter taste, detection of chemical stimulus|sensory detection of chemical stimulus during perception of bitter taste|sensory detection of bitter taste|sensory transduction of chemical stimulus during perception of bitter taste|bitter taste detection|perception of bitter taste, sensory transduction of chemical stimulus													biological_process											owl:Class	
GO:1905269	biolink:NamedThing	positive regulation of chromatin organization	Any process that activates or increases the frequency, rate or extent of chromatin organization.	got7fsn_ti	positive regulation of establishment or maintenance of chromatin architecture|up regulation of chromatin organisation|upregulation of establishment or maintenance of chromatin architecture|positive regulation of chromatin organisation|upregulation of chromatin organization|up-regulation of chromatin organisation|activation of establishment or maintenance of chromatin architecture|up-regulation of establishment or maintenance of chromatin architecture|activation of chromatin organization|up regulation of chromatin organization|upregulation of chromatin organisation|positive regulation of chromatin modification|up regulation of establishment or maintenance of chromatin architecture|up-regulation of chromatin organization|activation of chromatin organisation						pr	2016-06-15T20:14:56Z			GO:1903310			biological_process											owl:Class	
GO:1900243	biolink:NamedThing	negative regulation of synaptic vesicle endocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis.	got7fsn_ti	down regulation of synaptic vesicle retrieval|inhibition of synaptic vesicle endocytosis|inhibition of synaptic vesicle retrieval|down-regulation of synaptic vesicle endocytosis|down-regulation of synaptic vesicle retrieval|down regulation of synaptic vesicle endocytosis|downregulation of synaptic vesicle endocytosis|downregulation of synaptic vesicle retrieval|negative regulation of synaptic vesicle retrieval						rl	2012-03-28T01:40:36Z						biological_process											owl:Class	
GO:1904654	biolink:NamedThing	negative regulation of lung alveolus development	Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development.	got7fsn_ti	down-regulation of alveologenesis|negative regulation of alveologenesis|inhibition of alveologenesis|down-regulation of lung alveolus development|inhibition of lung alveolus development|downregulation of alveolarization|downregulation of lung alveolus development|down-regulation of alveolarization|down regulation of alveologenesis|downregulation of alveologenesis|down regulation of lung alveolus development|negative regulation of alveolarization|inhibition of alveolarization|down regulation of alveolarization						sl	2015-09-03T22:44:50Z						biological_process											owl:Class	
GO:1905199	biolink:NamedThing	manchette disassembly	The disaggregation of a manchette into its constituent components.	got7fsn_ti							krc	2016-05-12T15:19:16Z						biological_process											owl:Class	
GO:1900746	biolink:NamedThing	regulation of vascular endothelial growth factor signaling pathway	Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.	got7fsn_ti	regulation of vascular endothelial growth factor signalling pathway|regulation of VEGF-activated signaling pathway|regulation of VEGF signaling						pm	2012-05-29T08:28:06Z						biological_process											owl:Class	
GO:0015139	biolink:NamedThing	alpha-ketoglutarate transmembrane transporter activity	Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.	got7fsn_ti	2-oxoglutarate transporter activity											Reactome:R-HSA-372480		molecular_function											owl:Class	
GO:0015136	biolink:NamedThing	sialic acid transmembrane transporter activity	Enables the transfer of sialic acid from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0015739	biolink:NamedThing	sialic acid transport	The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0030095	biolink:NamedThing	chloroplast photosystem II	An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.	got7fsn_ti														cellular_component											owl:Class	
GO:0042934	biolink:NamedThing	achromobactin transmembrane transporter activity	Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other.	got7fsn_ti	achromobactin transporter activity													molecular_function											owl:Class	
GO:0033578	biolink:NamedThing	protein glycosylation in Golgi	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.	got7fsn_ti	protein amino acid glycosylation in Golgi|terminal glycosylation													biological_process											owl:Class	
GO:0015636	biolink:NamedThing	short-chain fatty acid transmembrane transporter activity	Enables the transfer of short-chain fatty acids from one side of a membrane to the other. Short-chain fatty acids are fatty acids with a chain length of less than C6.	got7fsn_ti	short-chain fatty acid transporter activity|short-chain fatty acid uptake transporter activity										GO:0015635			molecular_function											owl:Class	
GO:0015912	biolink:NamedThing	short-chain fatty acid transport	The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6.	got7fsn_ti														biological_process											owl:Class	
GO:0061713	biolink:NamedThing	anterior neural tube closure	The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.	got7fsn_ti							dph	2015-06-23T10:13:41Z						biological_process											owl:Class	
GO:0098896	biolink:NamedThing	postsynaptic early endosome membrane	The lipid bilayer surrounding a postsynaptic early endosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0043086	biolink:NamedThing	negative regulation of catalytic activity	Any process that stops or reduces the activity of an enzyme.	got7fsn_ti	down regulation of metalloenzyme activity|down regulation of enzyme activity|inhibition of metalloenzyme activity|down-regulation of metalloenzyme activity|downregulation of enzyme activity|downregulation of metalloenzyme activity|inhibition of enzyme activity|negative regulation of enzyme activity|negative regulation of metalloenzyme activity|down-regulation of enzyme activity										GO:0048553			biological_process											owl:Class	
GO:0015894	biolink:NamedThing	acriflavine transport	The directed movement of acriflavine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acriflavine is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.	got7fsn_ti	acriflavin transport													biological_process											owl:Class	
GO:0002796	biolink:NamedThing	positive regulation of antimicrobial peptide secretion	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.	got7fsn_ti	up regulation of antimicrobial peptide secretion|activation of antimicrobial peptide secretion|stimulation of antimicrobial peptide secretion|upregulation of antimicrobial peptide secretion|up-regulation of antimicrobial peptide secretion													biological_process											owl:Class	
GO:0017147	biolink:NamedThing	Wnt-protein binding	Binding to a Wnt-protein, a secreted growth factor involved in signaling.	got7fsn_ti														molecular_function											owl:Class	
GO:0042672	biolink:NamedThing	retinal cone cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0060789	biolink:NamedThing	hair follicle placode formation	The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.	got7fsn_ti							dph	2009-08-04T12:18:26Z						biological_process											owl:Class	
GO:0110112	biolink:NamedThing	regulation of lipid transporter activity	Any process that modulates the frequency, rate, or extent of lipid transporter activity.	got7fsn_ti							kmv	2018-07-06T18:53:55Z						biological_process											owl:Class	
SO:0000234	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015132	biolink:NamedThing	prostaglandin transmembrane transporter activity	Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.	got7fsn_ti	prostaglandin/thromboxane transporter activity											Reactome:R-HSA-879528|Reactome:R-HSA-5661188		molecular_function											owl:Class	
GO:0060882	biolink:NamedThing	basement membrane disassembly involved in semicircular canal fusion	A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion.	got7fsn_ti	basal lamina disassembly involved in semicircular canal fusion						dph	2009-08-13T11:29:52Z						biological_process											owl:Class	
GO:0009802	biolink:NamedThing	cinnamic acid ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid.	got7fsn_ti	cinnamic acid ester synthesis|phenylacrylic acid ester biosynthetic process|phenylacrylic acid ester biosynthesis|cinnamylic acid ester biosynthetic process|cinnamic acid ester formation|cinnamic acid ester biosynthesis|cinnamic acid ester anabolism|cinnamylic acid ester biosynthesis													biological_process											owl:Class	
GO:0009803	biolink:NamedThing	cinnamic acid metabolic process	The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid.	got7fsn_ti	phenylacrylic acid metabolic process|phenylpropenoic acid metabolic process|phenylpropenoic acid metabolism|cinnamylic acid metabolic process|cinnamylic acid metabolism|phenylacrylic acid metabolism|cinnamic acid metabolism													biological_process											owl:Class	
GO:0050852	biolink:NamedThing	T cell receptor signaling pathway	A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.	got7fsn_ti	T-lymphocyte receptor signalling pathway|T lymphocyte receptor signaling pathway|TCR signaling pathway|T-cell receptor signaling pathway|T-lymphocyte receptor signaling pathway|T-cell receptor signalling pathway|T lymphocyte receptor signalling pathway													biological_process											owl:Class	
GO:0039718	biolink:NamedThing	double membrane vesicle viral factory	A cytoplasmic viral factory that consists of a double-membrane bound vesicle. Has a diameter of 200-300nm and is derived from the endoplasmic reticulum or Golgi apparatus. Produced by Picornaviridae, Nidovirales, Arteriviridae and Coronaviridae.	got7fsn_ti	DMV viral factory						bf	2013-12-19T15:31:22Z						cellular_component											owl:Class	
GO:0010075	biolink:NamedThing	regulation of meristem growth	Any process involved in maintaining the size and shape of a meristem.	got7fsn_ti	regulation of meristem size													biological_process											owl:Class	
NCBITaxon:71193	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009320	biolink:NamedThing	phosphoribosylaminoimidazole carboxylase complex	A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity.	got7fsn_ti					See also the molecular function term 'phosphoribosylaminoimidazole carboxylase activity ; GO:0004638'.									cellular_component											owl:Class	
GO:0007371	biolink:NamedThing	ventral midline determination	The regionalization process in which the area where the ventral midline will form is specified.	got7fsn_ti	determination of posterior border of ventral midline|determination of anterior border of ventral midline										GO:0007373|GO:0007372			biological_process											owl:Class	
GO:0003038	biolink:NamedThing	detection of reduced oxygen by aortic body chemoreceptor signaling	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body.	got7fsn_ti	detection of reduced oxygen by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0042327	biolink:NamedThing	positive regulation of phosphorylation	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.	got7fsn_ti	up-regulation of phosphorylation|activation of phosphorylation|stimulation of phosphorylation|up regulation of phosphorylation|upregulation of phosphorylation													biological_process											owl:Class	
GO:1904719	biolink:NamedThing	positive regulation of AMPA glutamate receptor clustering	Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering.	got7fsn_ti	activation of AMPA receptor clustering|up-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|positive regulation of AMPA receptor clustering|up regulation of AMPA receptor clustering|positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|upregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|up-regulation of AMPA glutamate receptor clustering|activation of AMPA glutamate receptor clustering|activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|up regulation of AMPA glutamate receptor clustering|up-regulation of AMPA receptor clustering|upregulation of AMPA glutamate receptor clustering|up regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|upregulation of AMPA receptor clustering						hjd	2015-10-07T19:32:34Z						biological_process											owl:Class	
GO:1905775	biolink:NamedThing	negative regulation of DNA helicase activity	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity.	got7fsn_ti	inhibition of DNA helicase activity|downregulation of DNA helicase activity|down-regulation of ATP-dependent DNA helicase activity|downregulation of ATP-dependent DNA helicase activity|down regulation of ATP-dependent DNA helicase activity|negative regulation of ATP-dependent DNA helicase activity|inhibition of ATP-dependent DNA helicase activity|down regulation of DNA helicase activity|down-regulation of DNA helicase activity						rb	2013-10-15T21:20:01Z			GO:1902450			biological_process											owl:Class	
GO:0034897	biolink:NamedThing	4-(1-ethyl-1,4-dimethyl-pentyl)phenol monooxygenase activity	Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol.	got7fsn_ti												UM-BBD_reactionID:r1358		molecular_function											owl:Class	
GO:0035519	biolink:NamedThing	protein K29-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.	got7fsn_ti	protein K29-linked polyubiquitination						bf	2010-05-04T04:25:48Z						biological_process											owl:Class	
GO:0060207	biolink:NamedThing	diestrus	The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0050380	biolink:NamedThing	undecaprenyl-diphosphatase activity	Catalysis of the reaction:  di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate.	got7fsn_ti	C55-isoprenyl diphosphatase activity|C(55)-isoprenyl diphosphatase activity|C55-isoprenyl pyrophosphatase activity|undecaprenyl-diphosphate phosphohydrolase activity|C(55)-isoprenyl pyrophosphatase activity|isoprenyl pyrophosphatase activity	https://github.com/geneontology/go-ontology/issues/21789										RHEA:28094|EC:3.6.1.27|MetaCyc:UNDECAPRENYL-DIPHOSPHATASE-RXN|KEGG_REACTION:R05627		molecular_function											owl:Class	
GO:0032275	biolink:NamedThing	luteinizing hormone secretion	The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.	got7fsn_ti														biological_process											owl:Class	
GO:0070987	biolink:NamedThing	error-free translesion synthesis	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level.	got7fsn_ti					Note that 'error-free' does not mean that literally zero errors occur during DNA synthesis, but that the error rate is low, comparable to that of DNA synthesis during replication.		mah	2009-10-29T02:45:42Z						biological_process											owl:Class	
GO:0034818	biolink:NamedThing	ADD 9alpha-hydroxylase activity	Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin.	got7fsn_ti												UM-BBD_reactionID:r1149|EC:1.14.15.-		molecular_function											owl:Class	
GO:0015887	biolink:NamedThing	pantothenate transmembrane transport	The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	got7fsn_ti	pantothenate transport|vitamin B5 transport|pantothenate membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:0140382	biolink:NamedThing	tryptamine 4-monooxygenase activity	Catalysis of the reaction: tryptamine + reduced acceptor + O(2) <=> 4-hydroxytryptamine + acceptor + H(2)O.	got7fsn_ti							pg	2019-11-20T10:26:21Z				EC:1.14.99.59|RHEA:15865		molecular_function											owl:Class	
GO:0004642	biolink:NamedThing	phosphoribosylformylglycinamidine synthase activity	Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.	got7fsn_ti	formylglycinamide ribonucloetide amidotransferase activity|phosphoribosylformylglycineamidine synthetase activity|N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)|2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)|FGAM synthase activity|phosphoribosylformylglycinamidine synthetase activity|formylglycinamide ribotide amidotransferase activity|FGAM synthetase activity|5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)|FGAR amidotransferase activity|FGARAT activity											MetaCyc:FGAMSYN-RXN|RHEA:17129|EC:6.3.5.3|Reactome:R-HSA-73812|KEGG_REACTION:R04463		molecular_function											owl:Class	
GO:0050335	biolink:NamedThing	thiocyanate isomerase activity	Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate.	got7fsn_ti	isothiocyanate isomerase activity|benzyl-thiocyanate isomerase activity											EC:5.99.1.1|RHEA:10004|KEGG_REACTION:R04010|MetaCyc:THIOCYANATE-ISOMERASE-RXN		molecular_function											owl:Class	
GO:0106339	biolink:NamedThing	tRNA (cytidine 32-2'-O)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + cytosine32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine32 in tRNA.	got7fsn_ti							hjd	2020-11-05T22:48:53Z						molecular_function											owl:Class	
GO:0043258	biolink:NamedThing	laminin-9 complex	A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains.	got7fsn_ti	laminin-421 complex													cellular_component											owl:Class	
GO:0060397	biolink:NamedThing	growth hormone receptor signaling pathway via JAK-STAT	The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.	got7fsn_ti	JAK-STAT cascade involved in growth hormone signalling pathway													biological_process											owl:Class	
GO:0102730	biolink:NamedThing	cathasterone hydroxylase activity	Catalysis of the reaction: cathasterone + O2 + a reduced electron acceptor <=> teasterone + H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-716		molecular_function											owl:Class	
GO:0017174	biolink:NamedThing	glycine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine.	got7fsn_ti	S-adenosyl-L-methionine:glycine N-methyltransferase activity|glycine methyltransferase activity|S-adenosyl-L-methionine:glycine methyltransferase activity|GNMT											MetaCyc:2.1.1.162-RXN|EC:2.1.1.156|MetaCyc:GLYCINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.162|RHEA:19937|Reactome:R-HSA-6798317|EC:2.1.1.20|KEGG_REACTION:R00367		molecular_function											owl:Class	
GO:0030846	biolink:NamedThing	termination of RNA polymerase II transcription, poly(A)-coupled	The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination.	got7fsn_ti	transcription termination from Pol II promoter, poly(A) coupled|transcription termination from Pol II promoter, RNA polymerase(A) coupled|termination of RNA polymerase II transcription, polyadenylation-coupled													biological_process											owl:Class	
GO:0098017	biolink:NamedThing	viral capsid, major subunit	The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits.	got7fsn_ti	major head protein|major capsomere						bm	2012-07-19T11:21:21Z						cellular_component											owl:Class	
GO:0004060	biolink:NamedThing	arylamine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.	got7fsn_ti	p-aminosalicylate N-acetyltransferase activity|acetyl CoA-arylamine N-acetyltransferase activity|beta-naphthylamine N-acetyltransferase activity|4-aminobiphenyl N-acetyltransferase activity|arylamine acetyltransferase activity|acetyl-CoA:arylamine N-acetyltransferase activity|2-naphthylamine N-acetyltransferase activity|arylamine acetylase activity|indoleamine N-acetyltransferase activity											EC:2.3.1.5|UM-BBD_enzymeID:e0341|Reactome:R-HSA-174963|RHEA:16613|Reactome:R-HSA-174967|MetaCyc:ARYLAMINE-N-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0047977	biolink:NamedThing	hepoxilin-epoxide hydrolase activity	Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate.	got7fsn_ti	(5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate hydrolase activity|hepoxilin A(3) hydrolase activity|hepoxylin hydrolase activity|hepoxilin epoxide hydrolase activity|hepoxilin A3 hydrolase activity											Reactome:R-HSA-2161949|MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN|EC:3.3.2.7|RHEA:16665		molecular_function											owl:Class	
GO:0009342	biolink:NamedThing	glutamate synthase complex (NADPH)	A complex that possesses glutamate synthase (NADPH) activity.	got7fsn_ti														cellular_component											owl:Class	
GO:0102595	biolink:NamedThing	cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(6-O-(p-hydroxybenzoyl)-glucosyl)-oxybenzoyl)-glucoside) + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-15374		molecular_function											owl:Class	
GO:0003882	biolink:NamedThing	CDP-diacylglycerol-serine O-phosphatidyltransferase activity	Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.	got7fsn_ti	CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|CDP-diglyceride:serine phosphatidyltransferase activity|CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|CDPdiglyceride-serine O-phosphatidyltransferase activity|phosphatidylserine synthase activity|cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|PS synthase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|CDP-diglyceride-L-serine phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|serine exchange enzyme|CDP-diglycerine-serine O-phosphatidyltransferase activity|CDPdiacylglycerol-serine O-phosphatidyltransferase activity|phosphatidylserine synthetase activity											MetaCyc:PHOSPHASERSYN-RXN|RHEA:16913|EC:2.7.8.8		molecular_function											owl:Class	
GO:0034882	biolink:NamedThing	cis-aconitamide amidase activity	Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3.	got7fsn_ti												UM-BBD_reactionID:r1344		molecular_function											owl:Class	
GO:0047186	biolink:NamedThing	N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity	Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA.	got7fsn_ti	N-acetylneuraminate 7,8-O-acetyltransferase activity|N-acetylneuraminate 7(8)-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity|sialate O-acetyltransferase|N-acetylneuraminate O7-(or O9-)acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase activity|glycoprotein 7(9)-O-acetyltransferase activity											MetaCyc:2.3.1.45-RXN|RHEA:20808|EC:2.3.1.45		molecular_function											owl:Class	
GO:0016521	biolink:NamedThing	pituitary adenylate cyclase activating polypeptide activity	The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation.	got7fsn_ti	pituitary adenylyl cyclase activating polypeptide activity													molecular_function											owl:Class	
GO:0035624	biolink:NamedThing	receptor transactivation	The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer.	got7fsn_ti							bf	2010-12-08T04:18:18Z						biological_process											owl:Class	
GO:0140344	biolink:NamedThing	triglyceride transfer activity	Directly binding to a triglyceride and delivering it either to an acceptor molecule or to a specific location.	got7fsn_ti	triglyceride carrier activity						pg	2019-05-16T11:53:59Z						molecular_function											owl:Class	
GO:0018826	biolink:NamedThing	methionine gamma-lyase activity	Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate.	got7fsn_ti	L-methionine methanethiol-lyase (deaminating)|L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)|methionine lyase activity|L-methioninase activity|methionine dethiomethylase activity|L-methionine gamma-lyase activity|methioninase activity											MetaCyc:METHIONINE-GAMMA-LYASE-RXN|EC:4.4.1.11|UM-BBD_reactionID:r0432|RHEA:23800		molecular_function											owl:Class	
GO:0050341	biolink:NamedThing	thymine dioxygenase activity	Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2.	got7fsn_ti	5-hydroxymethyluracil oxygenase activity|thymine,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating)|5-hydroxy-methyluracil dioxygenase activity|thymine,2-oxoglutarate dioxygenase activity|thymine 7-hydroxylase activity											MetaCyc:THYMINE-DIOXYGENASE-RXN|RHEA:10316|EC:1.14.11.6		molecular_function											owl:Class	
GO:0031896	biolink:NamedThing	V2 vasopressin receptor binding	Binding to a V2 vasopressin receptor.	got7fsn_ti	V2 vasopressin receptor ligand													molecular_function											owl:Class	
GO:0047420	biolink:NamedThing	N-acyl-D-amino-acid deacylase activity	Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid.	got7fsn_ti	D-aminoacylase activity|N-acyl-D-amino acid amidohydrolase activity											MetaCyc:3.5.1.81-RXN|EC:3.5.1.81|RHEA:18309		molecular_function											owl:Class	
GO:0060064	biolink:NamedThing	Spemann organizer formation at the anterior end of the primitive streak	Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan.	got7fsn_ti	Spemann-Mangold organizer formation at the anterior end of the primitive streak|Spemann organizer formation in amniotes|Spemann's organizer formation at the anterior end of the primitive streak				Occurs in reptiles, birds and mammals.									biological_process											owl:Class	
GO:0018752	biolink:NamedThing	epsilon-caprolactam lactamase activity	Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate.	got7fsn_ti												UM-BBD_reactionID:r0448|MetaCyc:R561-RXN		molecular_function											owl:Class	
GO:0106290	biolink:NamedThing	trans-cinnamate-CoA ligase activity	Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate.	got7fsn_ti							hjd	2020-08-18T16:53:10Z				RHEA:64788		molecular_function											owl:Class	
GO:0009665	biolink:NamedThing	plastid inheritance	The partitioning of plastids between daughter cells at cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0004999	biolink:NamedThing	vasoactive intestinal polypeptide receptor activity	Combining with vasoactive intestinal polypeptide to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0098528	biolink:NamedThing	skeletal muscle fiber differentiation	The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.	got7fsn_ti							dos	2013-10-15T14:00:34Z						biological_process											owl:Class	
GO:0090574	biolink:NamedThing	RNA polymerase V transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter.	got7fsn_ti							tb	2014-05-09T13:26:16Z						cellular_component											owl:Class	
GO:0009764	biolink:NamedThing	PEP carboxykinase C4 photosynthesis	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK).	got7fsn_ti														biological_process											owl:Class	
GO:0001682	biolink:NamedThing	tRNA 5'-leader removal	Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.	got7fsn_ti	tRNA 5' leader removal													biological_process											owl:Class	
GO:0000333	biolink:NamedThing	telomerase catalytic core complex	The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition.	got7fsn_ti	TERT-TERC complex													cellular_component											owl:Class	
GO:0102726	biolink:NamedThing	DIMBOA glucoside beta-D-glucosidase activity	Catalysis of the reaction: (2R)-DIMBOA glucoside + H2O = H+ + DIMBOA + beta-D-glucose.	got7fsn_ti												MetaCyc:RXN-7082|RHEA:33975|EC:3.2.1.182		molecular_function											owl:Class	
CHEBI:24431	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018786	biolink:NamedThing	haloalkane dehalogenase activity	Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide.	got7fsn_ti	1-haloalkane dehalogenase activity|1-chlorohexane halidohydrolase activity|1-haloalkane halidohydrolase activity											EC:3.8.1.5|MetaCyc:HALOALKANE-DEHALOGENASE-RXN|RHEA:19081|UM-BBD_enzymeID:e0003		molecular_function											owl:Class	
GO:0032794	biolink:NamedThing	GTPase activating protein binding	Binding to a GTPase activating protein.	got7fsn_ti	GAP binding													molecular_function											owl:Class	
GO:0046512	biolink:NamedThing	sphingosine biosynthetic process	The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.	got7fsn_ti	sphingosine biosynthesis|sphingosine formation|sphingosine synthesis|sphingosine anabolism													biological_process											owl:Class	
GO:0001784	biolink:NamedThing	phosphotyrosine residue binding	Binding to a phosphorylated tyrosine residue within a protein.	got7fsn_ti	phosphotyrosine binding													molecular_function											owl:Class	
GO:0047166	biolink:NamedThing	1-alkenylglycerophosphoethanolamine O-acyltransferase activity	Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA.	got7fsn_ti	acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase activity											RHEA:16245|MetaCyc:2.3.1.121-RXN|EC:2.3.1.121		molecular_function											owl:Class	
GO:0004734	biolink:NamedThing	pyrimidodiazepine synthase activity	Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione.	got7fsn_ti	PDA synthase activity|pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)											EC:1.5.4.1|RHEA:10720|MetaCyc:1.5.4.1-RXN		molecular_function											owl:Class	
GO:0030596	biolink:NamedThing	alpha-L-rhamnosidase activity	Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.	got7fsn_ti	alpha-L-rhamnosidase N|alpha-L-rhamnoside rhamnohydrolase activity|alpha-L-rhamnosidase T											MetaCyc:3.2.1.40-RXN|EC:3.2.1.40		molecular_function											owl:Class	
GO:0047582	biolink:NamedThing	4-methyleneglutaminase activity	Catalysis of the reaction: 4-methylene-L-glutamine + H(2)O = 4-methylene-L-glutamate + NH(4)(+).	got7fsn_ti	4-methyleneglutamine amidohydrolase activity|4-methylene-L-glutamine amidohydrolase activity|4-methyleneglutamine deamidase activity											EC:3.5.1.67|KEGG_REACTION:R02712|RHEA:14741|MetaCyc:4-METHYLENEGLUTAMINASE-RXN		molecular_function											owl:Class	
GO:0035653	biolink:NamedThing	clathrin-coated vesicle cargo loading, AP-1-mediated	Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking.	got7fsn_ti	cargo loading into clathrin-coated vesicle, AP-1-mediated						bf	2011-01-25T11:01:38Z						biological_process											owl:Class	
GO:0097152	biolink:NamedThing	mesenchymal cell apoptotic process	Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.	got7fsn_ti	mesenchymal cell apoptosis						pr	2011-09-06T02:31:59Z						biological_process											owl:Class	
GO:0097407	biolink:NamedThing	Bunina body	Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles.	got7fsn_ti							pr	2012-10-31T13:52:30Z				NIF_Subcellular:nlx_subcell_20090101		cellular_component											owl:Class	
GO:0103054	biolink:NamedThing	gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)	Catalysis of the reaction: gibberellin A12 + O2 + 2-oxoglutarate <=> gibberellin A15 + carbon dioxide + succinate.	got7fsn_ti												RHEA:60776|MetaCyc:RXN1F-162		molecular_function											owl:Class	
GO:0047522	biolink:NamedThing	15-oxoprostaglandin 13-oxidase activity	Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.	got7fsn_ti	(5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity				Note that this is the reverse of the reaction described in '13-prostaglandin reductase activity ; GO:0036132'.							MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN|KEGG_REACTION:R04557|EC:1.3.1.48|KEGG_REACTION:R04556		molecular_function											owl:Class	
GO:0061776	biolink:NamedThing	topological DNA co-entrapment activity	A DNA binding activity in which a protein complex interacts with more than one DNA duplex to encircle the DNA molecules with a loose fitting ring.	got7fsn_ti	topological DNA entrapment activity	https://github.com/geneontology/go-ontology/issues/20522					dph	2016-07-13T13:10:15Z						molecular_function											owl:Class	
GO:0031802	biolink:NamedThing	type 5 metabotropic glutamate receptor binding	Binding to a type 5 metabotropic glutamate receptor.	got7fsn_ti	type 5 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0018812	biolink:NamedThing	3-hydroxyacyl-CoA dehydratase activity	Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).	got7fsn_ti												Reactome:R-HSA-8957389		molecular_function											owl:Class	
GO:0009255	biolink:NamedThing	Entner-Doudoroff pathway through 6-phosphogluconate	A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it.	got7fsn_ti												MetaCyc:ENTNER-DOUDOROFF-PWY-I		biological_process											owl:Class	
GO:0030883	biolink:NamedThing	endogenous lipid antigen binding	Binding to an endogenous cellular lipid antigen.	got7fsn_ti														molecular_function											owl:Class	
GO:0102188	biolink:NamedThing	4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O.	got7fsn_ti												MetaCyc:RXN-11956		molecular_function											owl:Class	
GO:0032998	biolink:NamedThing	Fc-epsilon receptor I complex	A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE.	got7fsn_ti	FceRI complex|immunoglobulin E receptor complex|IgE receptor complex													cellular_component											owl:Class	
GO:0050278	biolink:NamedThing	sedoheptulose-bisphosphatase activity	Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.	got7fsn_ti	sedoheptulose-1,7-bisphosphate 1-phosphohydrolase activity|sedoheptulose 1,7-bisphosphatase activity|sedoheptulose diphosphatase activity|sedoheptulose bisphosphatase activity|sedoheptulose 1,7-diphosphate phosphatase activity|SBPase activity|sedoheptulose-1,7-bisphosphatase activity|sedoheptulose 1,7-diphosphatase activity											EC:3.1.3.37|MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN|RHEA:17461		molecular_function											owl:Class	
GO:0098615	biolink:NamedThing	dimethyl selenide methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium.	got7fsn_ti												Reactome:R-HSA-2408554		molecular_function											owl:Class	
GO:0010424	biolink:NamedThing	DNA methylation on cytosine within a CG sequence	The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule.	got7fsn_ti	cytosine methylation within a CG sequence													biological_process											owl:Class	
GO:0102742	biolink:NamedThing	R(+)-3,4-dihydroxyphenyllactate:NADP+ oxidoreductase activity	Catalysis of the reaction: H+ + 3,4-dihydroxyphenylpyruvate + NADPH <=> (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP.	got7fsn_ti												EC:1.1.1.237|MetaCyc:RXN-7632		molecular_function											owl:Class	
GO:0003910	biolink:NamedThing	DNA ligase (ATP) activity	Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).	got7fsn_ti	poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)|deoxyribonucleic ligase|DNA repair enzyme activity|deoxyribonucleic repair enzyme|deoxyribonucleic acid joinase|deoxyribonucleic acid ligase|deoxyribonucleic joinase|polynucleotide ligase (ATP) activity|polynucleotide ligase|deoxyribonucleic acid repair enzyme|DNA-joining enzyme|DNA joinase activity|deoxyribonucleic-joining enzyme|polydeoxyribonucleotide synthase (ATP) activity|deoxyribonucleic acid-joining enzyme|deoxyribonucleate ligase|sealase activity											EC:6.5.1.1|MetaCyc:DNA-LIGASE-ATP-RXN		molecular_function											owl:Class	
GO:0102249	biolink:NamedThing	phosphatidylcholine:diacylglycerol cholinephosphotransferase activity	Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine.	got7fsn_ti												MetaCyc:RXN-12386		molecular_function											owl:Class	
GO:0090548	biolink:NamedThing	response to nitrate starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate.	got7fsn_ti							tb	2013-04-22T13:57:16Z						biological_process											owl:Class	
GO:0050126	biolink:NamedThing	N-carbamoylputrescine amidase activity	Catalysis of the reaction: N-carbamoylputrescine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + putrescine.	got7fsn_ti	NCP|N-carbamoylputrescine amidohydrolase activity|carbamoylputrescine hydrolase activity											KEGG_REACTION:R01152|RHEA:22284|EC:3.5.1.53|MetaCyc:N-CARBAMOYLPUTRESCINE-AMIDASE-RXN		molecular_function											owl:Class	
GO:0102461	biolink:NamedThing	kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> kaempferol 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP.	got7fsn_ti												MetaCyc:RXN-14009		molecular_function											owl:Class	
GO:1990651	biolink:NamedThing	inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate.	got7fsn_ti							al	2015-02-23T11:17:19Z						molecular_function											owl:Class	
GO:0035164	biolink:NamedThing	embryonic plasmatocyte differentiation	The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.	got7fsn_ti	embryonic plasmatocyte cell differentiation													biological_process											owl:Class	
GO:0106316	biolink:NamedThing	nitrite reductase NADH activity	Catalysis of the reaction: ammonium hydroxide + 3 NAD+ + H2O = nitrite + 3 NADH + 3 H+.	got7fsn_ti							hjd	2020-09-23T14:34:02Z				RHEA:24628		molecular_function											owl:Class	
GO:0070528	biolink:NamedThing	protein kinase C signaling	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	protein kinase C signaling cascade|PKC signaling cascade|protein kinase C signalling cascade|PKC signal transduction|protein kinase C signal transduction													biological_process											owl:Class	
GO:0050199	biolink:NamedThing	piperidine N-piperoyltransferase activity	Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H(+).	got7fsn_ti	(E,E)-piperoyl-CoA:piperidine N-piperoyltransferase activity|piperoyl-CoA:piperidine N-piperoyltransferase activity|piperidine piperoyltransferase activity											EC:2.3.1.145|KEGG_REACTION:R03994|MetaCyc:PIPERIDINE-N-PIPEROYLTRANSFERASE-RXN|RHEA:14561		molecular_function											owl:Class	
GO:0035971	biolink:NamedThing	peptidyl-histidine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.	got7fsn_ti							bf	2011-08-08T03:26:02Z						biological_process											owl:Class	
GO:0038195	biolink:NamedThing	urokinase plasminogen activator signaling pathway	A series of molecular signals initiated by the binding of urokinase plasminogen activator to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	uPA signaling pathway						bf	2013-10-28T09:14:13Z						biological_process											owl:Class	
GO:0005147	biolink:NamedThing	oncostatin-M receptor binding	Binding to an oncostatin-M receptor.	got7fsn_ti	oncostatin-M|oncostatin-M receptor ligand													molecular_function											owl:Class	
GO:0050142	biolink:NamedThing	nitrogenase (flavodoxin) activity	Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate.	got7fsn_ti	reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing)											MetaCyc:NITROGENASE-FLAVODOXIN-RXN|RHEA:15645|EC:1.19.6.1		molecular_function											owl:Class	
GO:0031417	biolink:NamedThing	NatC complex	A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p.	got7fsn_ti	N-terminal acetyltransferase C complex													cellular_component											owl:Class	
GO:0097463	biolink:NamedThing	gemmule	Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex.	got7fsn_ti							pr	2012-12-21T07:59:04Z				NIF_Subcellular:nlx_subcell_1005003		cellular_component											owl:Class	
GO:0071179	biolink:NamedThing	MAML3-RBP-Jkappa-ICN1 complex	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML3-RBP-Jkappa-Notch1 complex						mah	2009-11-23T02:50:39Z						cellular_component											owl:Class	
GO:0102027	biolink:NamedThing	S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity	Catalysis of the reaction: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> menaquinol-8 + H+ + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.163|MetaCyc:ADOMET-DMK-METHYLTRANSFER-RXN|RHEA:30063		molecular_function											owl:Class	
GO:0060798	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate.	got7fsn_ti	transforming growth factor beta receptor signalling pathway involved in mesodermal cell fate specification						dph	2009-08-06T11:16:11Z						biological_process											owl:Class	
GO:0102365	biolink:NamedThing	taxusin 2-alpha-hydroxylase activity	Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-13486		molecular_function											owl:Class	
GO:0072435	biolink:NamedThing	response to mitotic G2 DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling.	got7fsn_ti	mitotic G2/M transition decatenation checkpoint effector process|response to mitotic G2/M transition DNA damage checkpoint signaling|response to signal involved in mitotic G2/M transition DNA damage checkpoint|mitotic G2/M transition DNA damage checkpoint effector process|response to signal involved in mitotic G2/M transition decatenation checkpoint|response to mitotic G2/M transition decatenation checkpoint signaling						mah	2010-12-08T04:44:01Z			GO:0072458			biological_process											owl:Class	
GO:0071311	biolink:NamedThing	cellular response to acetate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.	got7fsn_ti							mah	2009-12-10T04:48:16Z						biological_process											owl:Class	
GO:0106234	biolink:NamedThing	outer membrane protein complex	Any protein complex that is part of the bacterial outer membrane. An example In E.coli, is RcsF associated with any one of several outer membrane beta-barrel proteins (OMPs), such as OmpA, OmpF, or OmpcC.	got7fsn_ti							hjd	2019-11-07T19:20:43Z						cellular_component											owl:Class	
GO:0018403	biolink:NamedThing	protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.	got7fsn_ti	protein-dermatan sulphate linkage via dermatan 4-sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine											RESID:AA0209		biological_process											owl:Class	
GO:0051009	biolink:NamedThing	O-acetylhomoserine sulfhydrylase activity	Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate.	got7fsn_ti												RHEA:27822|MetaCyc:ACETYLHOMOSER-CYS-RXN		molecular_function											owl:Class	
GO:0051935	biolink:NamedThing	glutamate reuptake	The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	got7fsn_ti	glutamate recycling|L-glutamate uptake involved in synaptic transmission|glutamate import into neuron|glutamate import into glial cell|glutamate uptake during transmission of nerve impulse|L-glutamate reuptake|L-glutamate uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0098712	biolink:NamedThing	L-glutamate import across plasma membrane	The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-glutamate import into cell|L-glutamate(1-) import into cell|L-glutamate(1-) import across plasma membrane						mah	2013-06-12T12:32:47Z			GO:1990123|GO:1903802			biological_process											owl:Class	
GO:0102953	biolink:NamedThing	hypoglycin A gamma-glutamyl transpeptidase activity	Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B.	got7fsn_ti												MetaCyc:RXN-9157|EC:2.3.2.2		molecular_function											owl:Class	
GO:0034717	biolink:NamedThing	Gemin6-Gemin7-unrip complex	A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly.	got7fsn_ti														cellular_component											owl:Class	
GO:0004350	biolink:NamedThing	glutamate-5-semialdehyde dehydrogenase activity	Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP(+) + phosphate = L-glutamyl 5-phosphate + H(+) + NADPH.	got7fsn_ti	glutamate-phosphate reductase activity|gamma-glutamylphosphate reductase activity|L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)|gamma-glutamyl phosphate reductase activity|glutamate semialdehyde dehydrogenase activity|glutamylphosphate reductase activity|glutamate-gamma-semialdehyde dehydrogenase activity|glutamyl-gamma-semialdehyde dehydrogenase activity|beta-glutamylphosphate reductase activity										GO:0001513	KEGG_REACTION:R03313|RHEA:19541|MetaCyc:GLUTSEMIALDEHYDROG-RXN|EC:1.2.1.41		molecular_function											owl:Class	
GO:0001785	biolink:NamedThing	prostaglandin J receptor activity	Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.	got7fsn_ti	PGJ receptor activity|PGJ(2) receptor activity													molecular_function											owl:Class	
GO:1900818	biolink:NamedThing	ochratoxin A biosynthetic process	The chemical reactions and pathways resulting in the formation of ochratoxin A.	got7fsn_ti	Ochratoxin A synthesis|Ochratoxin A biosynthetic process|Ochratoxin A anabolism|Ochratoxin A formation|Ochratoxin A biosynthesis						di	2012-06-04T10:13:32Z						biological_process											owl:Class	
GO:0008706	biolink:NamedThing	6-phospho-beta-glucosidase activity	Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose.	got7fsn_ti	phospho-beta-glucosidase activity|phospho-beta-glucosidase A|phosphocellobiase activity|6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase activity											RHEA:10772|EC:3.2.1.86|MetaCyc:6-PHOSPHO-BETA-GLUCOSIDASE-RXN		molecular_function											owl:Class	
GO:0097676	biolink:NamedThing	histone H3-K36 dimethylation	The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone.	got7fsn_ti							pr	2014-11-04T10:38:05Z						biological_process											owl:Class	
GO:0052797	biolink:NamedThing	4-O-methyl-glucuronoyl methylesterase activity	Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X].	got7fsn_ti	glucuronoyl esterase activity													molecular_function											owl:Class	
GO:0035538	biolink:NamedThing	carbohydrate response element binding	Binding to a carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes.	got7fsn_ti	ChoRE binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		bf	2010-05-07T10:48:30Z						molecular_function											owl:Class	
GO:0042835	biolink:NamedThing	BRE binding	Binding to a BRE RNA element (Bruno response element).	got7fsn_ti														molecular_function											owl:Class	
GO:0004096	biolink:NamedThing	catalase activity	Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.	got7fsn_ti	CAT|heme catalase activity|caperase activity|haem catalase activity|manganese catalase activity|catalase-peroxidase activity|optidase activity|hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|bacterial catalase-peroxidase activity|catalase reaction|equilase activity										GO:0016952|GO:0016953	UM-BBD_enzymeID:e0834|RHEA:20309|EC:1.11.1.6|Reactome:R-HSA-76031|Reactome:R-HSA-1222704|MetaCyc:CATAL-RXN		molecular_function											owl:Class	
GO:0036219	biolink:NamedThing	GTP diphosphatase activity	Catalysis of the reaction: GTP + H2O = GMP + diphosphate.	got7fsn_ti	GTP diphosphohydrolase activity|GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase						bf	2012-05-08T01:47:59Z				KEGG_REACTION:R00426|RHEA:29391		molecular_function											owl:Class	
GO:0047158	biolink:NamedThing	sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity	Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose.	got7fsn_ti	1-(hydroxycinnamoyl)-glucose:1-(hydroxycinnamoyl)-glucose hydroxycinnamoyltransferase activity|hydroxycinnamoylglucose-hydroxycinnamoylglucose hydroxycinnamoyltransferase activity|1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucoside:1-O-(4-hydroxy-3,5-dimethoxycinnamoyl-beta-D-glucoside 1-O-sinapoyltransferase activity											KEGG_REACTION:R00063|MetaCyc:2.3.1.103-RXN|RHEA:22664|EC:2.3.1.103		molecular_function											owl:Class	
GO:0047352	biolink:NamedThing	adenylylsulfate-ammonia adenylyltransferase activity	Catalysis of the reaction: 5'-adenylyl sulfate + NH(4)(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate.	got7fsn_ti	adenylylsulfate:ammonia adenylyltransferase activity|adenylylsulphate-ammonia adenylyltransferase activity|APSAT											RHEA:19197|KEGG_REACTION:R01619|MetaCyc:2.7.7.51-RXN|EC:2.7.7.51		molecular_function											owl:Class	
GO:0070383	biolink:NamedThing	DNA cytosine deamination	The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.	got7fsn_ti														biological_process											owl:Class	
GO:0070689	biolink:NamedThing	L-threonine catabolic process to propionate	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.	got7fsn_ti	threonine catabolic process to propionate|L-threonine degradation to propionate|L-threonine breakdown to propionate|L-threonine catabolism to propionate						mah	2009-06-03T01:36:54Z				MetaCyc:PWY-5437		biological_process											owl:Class	
GO:0001093	biolink:NamedThing	TFIIB-class transcription factor binding	Binding to a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	got7fsn_ti							krc	2010-10-28T02:46:15Z						molecular_function											owl:Class	
GO:0052577	biolink:NamedThing	germacrene-D synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-germacrene D + diphosphate.	got7fsn_ti	2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(-)-Germacrene D-forming] activity						ai	2010-08-09T01:39:02Z				KEGG_REACTION:R07648|RHEA:12016|EC:4.2.3.22|MetaCyc:RXN-8562		molecular_function											owl:Class	
GO:0042313	biolink:NamedThing	protein kinase C deactivation	Any process resulting in the inhibition or termination of the activity of protein kinase C.	got7fsn_ti	PKC deactivation													biological_process											owl:Class	
GO:0046185	biolink:NamedThing	aldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.	got7fsn_ti	aldehyde degradation|aldehyde breakdown|aldehyde catabolism													biological_process											owl:Class	
GO:0032209	biolink:NamedThing	positive regulation of telomere maintenance via recombination	Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.	got7fsn_ti	up-regulation of telomere maintenance via recombination|upregulation of telomere maintenance via recombination|activation of telomere maintenance via recombination|up regulation of telomere maintenance via recombination|stimulation of telomere maintenance via recombination													biological_process											owl:Class	
GO:0019962	biolink:NamedThing	type I interferon binding	Binding to a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	interferon-alpha/beta binding|type I IFN binding|interferon-kappa binding|interferon-delta binding|interferon-tau binding|interferon-omega binding|interferon-alpha binding|interferon-zeta binding|interferon-beta binding|interferon-epsilon binding													molecular_function											owl:Class	
GO:0043896	biolink:NamedThing	glucan 1,6-alpha-glucosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.	got7fsn_ti	glucodextrinase|exo-1,6-alpha-glucosidase activity|glucan alpha-1,6-D-glucohydrolase activity|exo-1,6-beta-glucosidase|glucodextranase activity|glucan-1,6-alpha-glucosidase activity											MetaCyc:3.2.1.70-RXN|EC:3.2.1.70		molecular_function											owl:Class	
GO:0047331	biolink:NamedThing	diphosphate-glycerol phosphotransferase activity	Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H(+) + phosphate.	got7fsn_ti	pyrophosphate--glycerol phosphotransferase activity|PPi-glycerol phosphotransferase activity|diphosphate:glycerol 1-phosphotransferase activity											MetaCyc:2.7.1.79-RXN|EC:2.7.1.79|KEGG_REACTION:R01044|RHEA:13689		molecular_function											owl:Class	
GO:0005174	biolink:NamedThing	CD40 receptor binding	Binding to CD40, a receptor found on the surface of all B-lymphocytes.	got7fsn_ti														molecular_function											owl:Class	
GO:0004591	biolink:NamedThing	oxoglutarate dehydrogenase (succinyl-transferring) activity	Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.	got7fsn_ti	2-ketoglutarate dehydrogenase activity|alpha-ketoglutaric dehydrogenase activity|alpha-ketoglutarate dehydrogenase activity|alpha-oxoglutarate dehydrogenase activity|oxoglutarate dehydrogenase (lipoamide) activity|2-oxoglutarate: lipoate oxidoreductase activity|oxoglutarate dehydrogenase activity|alpha-ketoglutaric acid dehydrogenase activity|2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity|OGDC activity|2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)|oxoglutarate decarboxylase activity|ketoglutaric dehydrogenase activity|AKGDH activity|2-oxoglutarate dehydrogenase activity											MetaCyc:2OXOGLUTDECARB-RXN|EC:1.2.4.2|RHEA:12188		molecular_function											owl:Class	
GO:0047100	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity	Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate.	got7fsn_ti	glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating)|D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)|NADP-triose phosphate dehydrogenase activity|triosephosphate dehydrogenase (NADP)|triosephosphate dehydrogenase (NADP+) activity|triosephosphate dehydrogenase (NADP(+)) activity|dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating)|NADP-dependent glyceraldehyde-3-phosphate dehydrogenase activity|NADP-dependent glyceraldehyde phosphate dehydrogenase activity											MetaCyc:1.2.1.13-RXN|EC:1.2.1.13|RHEA:10296		molecular_function											owl:Class	
GO:0001918	biolink:NamedThing	farnesylated protein binding	Binding to a farnesylated protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0033767	biolink:NamedThing	4-hydroxyacetophenone monooxygenase activity	Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+).	got7fsn_ti	(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming) activity|HAPMO											KEGG_REACTION:R06892|RHEA:22916|EC:1.14.13.84|UM-BBD_reactionID:r0756|MetaCyc:1.14.13.84-RXN		molecular_function											owl:Class	
GO:0102810	biolink:NamedThing	glutarate-semialdehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+.	got7fsn_ti												RHEA:57832|MetaCyc:RXN-8182		molecular_function											owl:Class	
GO:0050084	biolink:NamedThing	mannitol-1-phosphatase activity	Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate.	got7fsn_ti	D-mannitol-1-phosphate phosphohydrolase activity|mannitol-1-phosphate phosphatase activity											KEGG_REACTION:R02167|EC:3.1.3.22|RHEA:19537|MetaCyc:MANNITOL-1-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:1990874	biolink:NamedThing	vascular associated smooth muscle cell proliferation	The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	got7fsn_ti	VSMC proliferation|vascular smooth muscle cell proliferation						sl	2015-09-29T16:34:59Z						biological_process											owl:Class	
GO:0048659	biolink:NamedThing	smooth muscle cell proliferation	The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.	got7fsn_ti	SMC proliferation													biological_process											owl:Class	
GO:0038048	biolink:NamedThing	dynorphin receptor activity	Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin.	got7fsn_ti	kappa-opioid receptor activity						bf	2011-11-14T01:48:02Z						molecular_function											owl:Class	
GO:0009762	biolink:NamedThing	NADP-malic enzyme C4 photosynthesis	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme.	got7fsn_ti												MetaCyc:PWY-241		biological_process											owl:Class	
GO:0031994	biolink:NamedThing	insulin-like growth factor I binding	Binding to insulin-like growth factor I.	got7fsn_ti	IGF-I binding													molecular_function											owl:Class	
GO:0047120	biolink:NamedThing	(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity	Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO(2) + NADH.	got7fsn_ti	cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)|(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase activity|terephthalate 1,2-cis-dihydrodiol dehydrogenase activity|dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity|(1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity										GO:0018514	UM-BBD_reactionID:r0151|RHEA:10744|MetaCyc:1.3.1.53-RXN|EC:1.3.1.53|KEGG_REACTION:R01633		molecular_function											owl:Class	
GO:0008921	biolink:NamedThing	lipopolysaccharide-1,6-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide.	got7fsn_ti	LPS-1,6-galactosyltransferase activity													molecular_function											owl:Class	
GO:0090591	biolink:NamedThing	protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetyl-mannosamine(out) = protein histidine +N-acetyl- mannosamine-6-phosphate(in).	got7fsn_ti							tb	2014-06-04T16:33:01Z						molecular_function											owl:Class	
GO:0102903	biolink:NamedThing	gamma-terpinene synthase activity	Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8547|RHEA:32559|EC:4.2.3.114		molecular_function											owl:Class	
GO:0140373	biolink:NamedThing	histone H3-K14 ubiquitination	The modification of histone H3 by the addition of one or more ubiquitin groups to a lysine residue at position 14 of the histone.	got7fsn_ti	histone H3K14 ubiquitination|histone H3 ubiquitination at K14|histone H3-K14 ubiquitylation						pg	2019-10-03T15:31:15Z						biological_process											owl:Class	
GO:0030962	biolink:NamedThing	peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine	The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine.	got7fsn_ti												RESID:AA0369		biological_process											owl:Class	
GO:0033992	biolink:NamedThing	1,5-anhydro-D-fructose dehydratase activity	Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O.	got7fsn_ti	1,5-anhydro-D-fructose 4-dehydratase activity|1,5-anhydro-D-fructose hydro-lyase activity|1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming) activity|1,5-anhydro-D-fructose hydrolyase activity|AF dehydratase activity|1,5-anhydro-D-arabino-hex-2-ulose dehydratase activity|AFDH											MetaCyc:4.2.1.111-RXN|EC:4.2.1.111|RHEA:15725		molecular_function											owl:Class	
GO:0052875	biolink:NamedThing	riboflavin reductase (NADH) activity	Catalysis of the reaction: reduced riboflavin + NAD+ = riboflavin + NADH + 2 H+.	got7fsn_ti	riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide) reductase activity|NAD(P)H:riboflavin oxidoreductase activity|riboflavine mononucleotide reductase activity|riboflavin mononucleotide reductase activity|flavin mononucleotide reductase activity|flavine mononucleotide reductase activity|NAD(P)H:FMN oxidoreductase activity|NAD(P)H2 dehydrogenase (FMN) activity|NAD(P)H-FMN reductase activity|NAD(P)H2:FMN oxidoreductase activity|NAD(P)H-dependent FMN reductase activity											EC:1.5.1.41|MetaCyc:RXN-12445|RHEA:31455|KEGG_REACTION:R09750		molecular_function											owl:Class	
GO:1900812	biolink:NamedThing	helvolic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of helvolic acid.	got7fsn_ti	helvolic acid anabolism|Fumigacin biosynthesis|Fumigacin synthesis|Fumigacin anabolism|Fumigacin formation|helvolic acid synthesis|Fumigacin biosynthetic process|helvolic acid formation|helvolic acid biosynthesis						di	2012-06-04T10:02:58Z						biological_process											owl:Class	
GO:0042559	biolink:NamedThing	pteridine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.	got7fsn_ti	pteridine and derivative biosynthesis|pteridine-containing compound biosynthesis|pterin biosynthesis|pterin biosynthetic process|pteridine-containing compound formation|pteridine-containing compound synthesis|pteridine and derivative biosynthetic process|pteridine-containing compound anabolism													biological_process											owl:Class	
GO:0072535	biolink:NamedThing	tumor necrosis factor (ligand) superfamily member 11 production	The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	tumor necrosis factor ligand superfamily member 11 production|RANKL production|TNFSF11 production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		mah	2011-01-14T01:42:23Z						biological_process											owl:Class	
GO:1990294	biolink:NamedThing	peptidyl-threonine trans-autophosphorylation	The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.	got7fsn_ti							al	2014-02-05T12:42:46Z						biological_process											owl:Class	
GO:0046088	biolink:NamedThing	cytidine biosynthetic process	The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside.	got7fsn_ti	cytidine synthesis|cytidine biosynthesis|cytidine anabolism|cytidine formation													biological_process											owl:Class	
GO:0018222	biolink:NamedThing	peptidyl-L-cysteine methyl disulfide biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-L-cysteine methyl disulfide.	got7fsn_ti	peptidyl-L-cysteine methyl disulphide biosynthetic process from peptidyl-cysteine|peptidyl-L-cysteine methyl disulphide biosynthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide synthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide formation from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide anabolism from peptidyl-cysteine											RESID:AA0101		biological_process											owl:Class	
GO:0055048	biolink:NamedThing	anastral spindle assembly	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0103011	biolink:NamedThing	mannosylfructose-phosphate synthase activity	Catalysis of the reaction: GDP-alpha-D-mannose + beta-D-fructofuranose 6-phosphate <=> mannosylfructose-phosphate + GDP.	got7fsn_ti												RHEA:26039|EC:2.4.1.246|MetaCyc:RXN-9935		molecular_function											owl:Class	
GO:0090008	biolink:NamedThing	hypoblast development	The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast.	got7fsn_ti							tb	2009-07-29T10:25:54Z						biological_process											owl:Class	
GO:0008692	biolink:NamedThing	3-hydroxybutyryl-CoA epimerase activity	Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.	got7fsn_ti	3-hydroxybutanoyl-CoA 3-epimerase activity|3-hydroxyacyl-CoA epimerase activity|3-hydroxybutyryl coenzyme A epimerase activity											EC:5.1.2.3|MetaCyc:OHBUTYRYL-COA-EPIM-RXN|RHEA:21760		molecular_function											owl:Class	
GO:0019031	biolink:NamedThing	viral envelope	The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.	got7fsn_ti	viral glycoprotein|viral outside membrane											Wikipedia:Viral_envelope		cellular_component											owl:Class	
GO:0140261	biolink:NamedThing	BCOR complex	A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10.	got7fsn_ti	BCOR/BCORL1 complex|PRC1.1 complex|BCL6 corepressor (BCOR) complex|non-canonical BCOR-PRC1.1 complex|non-canonical PRC1-BCOR complex						pg	2018-09-11T09:35:05Z						cellular_component											owl:Class	
GO:0047219	biolink:NamedThing	monoterpenol beta-glucosyltransferase activity	Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H(+) + UDP.	got7fsn_ti	UDP-glucose:(-)-menthol O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-monoterpenol glucosyltransferase activity|UDPglucose:monoterpenol glucosyltransferase activity|UDPglucose:(-)-menthol O-beta-D-glucosyltransferase activity											MetaCyc:2.4.1.127-RXN|EC:2.4.1.127|RHEA:11520|KEGG_REACTION:R02179		molecular_function											owl:Class	
GO:0047460	biolink:NamedThing	L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity	Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H(2)O = 2-oxopent-4-enoate + chloride + H(+) + NH(4)(+).	got7fsn_ti	L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating)|L-2-amino-4-chloro-4-pentenoate dehalogenase activity|L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H2O; deaminating; 2-oxopent-4-enoate-forming)											MetaCyc:4.5.1.4-RXN|KEGG_REACTION:R02605|RHEA:11620|EC:4.5.1.4		molecular_function											owl:Class	
GO:0102436	biolink:NamedThing	7-methylmyricetin 4'-O-methyltransferase activity	Catalysis of the reaction: 7-O-methylmyricetin + S-adenosyl-L-methionine  <=> 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-13911		molecular_function											owl:Class	
GO:0018115	biolink:NamedThing	peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine.	got7fsn_ti	peptidyl-S-diphytanylglycerol diether-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-diphytanylglycerol diether-L-cysteine formation from peptidyl-cysteine|peptidyl-S-diphytanylglycerol diether-L-cysteine synthesis from peptidyl-cysteine											RESID:AA0223		biological_process											owl:Class	
GO:0004593	biolink:NamedThing	pantothenase activity	Catalysis of the reaction: (R)-pantothenate + H(2)O = (R)-pantoate + beta-alanine.	got7fsn_ti	(R)-pantothenate amidohydrolase activity|pantothenate amidohydrolase activity|pantothenate hydrolase activity											EC:3.5.1.22|MetaCyc:PANTOTHENASE-RXN|RHEA:12448|KEGG_REACTION:R02474		molecular_function											owl:Class	
GO:0061623	biolink:NamedThing	glycolytic process from galactose	The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.	got7fsn_ti							dph	2014-04-28T08:13:38Z						biological_process											owl:Class	
GO:0150087	biolink:NamedThing	multiple synapse bouton, contacting single dendrite	A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite.	got7fsn_ti	MSB1|type 1 multiple-synapse bouton|type 1 multi-synapse bouton|type 1 multisynaptic bouton|type 1 multiple spine synapse bouton|type 1 multisynapse bouton|type 1 multi-synaptic bouton						bc	2018-08-08T13:26:34Z						cellular_component											owl:Class	
GO:0047802	biolink:NamedThing	cysteine-conjugate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate.	got7fsn_ti	S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase activity|cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1)|cysteine conjugate aminotransferase activity											RHEA:13485|MetaCyc:CYSTEINE-CONJUGATE-TRANSAMINASE-RXN|EC:2.6.1.75|KEGG_REACTION:R04338		molecular_function											owl:Class	
GO:0022022	biolink:NamedThing	septal cell proliferation	The multiplication or reproduction of septal cells, resulting in the expansion of a cell population.	got7fsn_ti	septum cell proliferation													biological_process											owl:Class	
GO:0008260	biolink:NamedThing	3-oxoacid CoA-transferase activity	Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA.	got7fsn_ti	3-ketoacid CoA-transferase activity|succinyl coenzyme A-acetoacetyl coenzyme A-transferase activity|acetoacetate succinyl-CoA transferase activity|succinyl-CoA:3-ketoacid-CoA transferase activity|succinyl-CoA:3-oxo-acid CoA-transferase activity|3-ketoacid coenzyme A transferase activity|3-oxoacid CoA dehydrogenase activity|succinyl-CoA transferase activity|3-oxo-CoA transferase activity|acetoacetyl coenzyme A-succinic thiophorase activity|3-oxoacid coenzyme A-transferase activity											EC:2.8.3.5|RHEA:25480|Reactome:R-HSA-74177|MetaCyc:3-OXOACID-COA-TRANSFERASE-RXN		molecular_function											owl:Class	
GO:0070662	biolink:NamedThing	mast cell proliferation	The expansion of a mast cell population by cell division.	got7fsn_ti							mah	2009-05-28T05:27:51Z						biological_process											owl:Class	
GO:0097011	biolink:NamedThing	cellular response to granulocyte macrophage colony-stimulating factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.	got7fsn_ti	cellular response to GM-CSF stimulus						pr	2011-03-21T05:25:06Z						biological_process											owl:Class	
GO:0033798	biolink:NamedThing	thyroxine 5-deiodinase activity	Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2.	got7fsn_ti	iodothyronine inner ring monodeiodinase activity|acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity|inner ring-deiodinating pathway|diiodothyronine 5'-deiodinase activity|type III iodothyronine deiodinase activity|iodothyronine 5-deiodinase activity											EC:1.21.99.3|MetaCyc:1.97.1.11-RXN|RHEA:18897		molecular_function											owl:Class	
GO:0005920	biolink:NamedThing	smooth septate junction	A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.	got7fsn_ti	zonula continua													cellular_component											owl:Class	
GO:0050591	biolink:NamedThing	quinine 3-monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+).	got7fsn_ti	quinine 3-hydroxylase activity|nifedipine oxidase activity|quinine,NADPH:oxygen oxidoreductase activity											EC:1.14.14.55|MetaCyc:1.14.13.67-RXN|KEGG_REACTION:R05727|RHEA:20149		molecular_function											owl:Class	
GO:0071308	biolink:NamedThing	cellular response to menaquinone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.	got7fsn_ti	cellular response to menatetrenone|cellular response to vitamin K2						mah	2009-12-10T04:37:08Z						biological_process											owl:Class	
GO:0102678	biolink:NamedThing	22-alpha-hydroxy-campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity	Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + NADP <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH.	got7fsn_ti												MetaCyc:RXN-4229		molecular_function											owl:Class	
GO:0071192	biolink:NamedThing	Kv4.2-KChIP1 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2.	got7fsn_ti							mah	2009-11-23T04:51:42Z				CORUM:606		cellular_component											owl:Class	
GO:0032615	biolink:NamedThing	interleukin-12 production	The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL-12 production|interleukin-12 secretion|NKSF production|CLMF production|interleukin-12 biosynthetic process										GO:0072610|GO:0042090			biological_process											owl:Class	
GO:1900353	biolink:NamedThing	positive regulation of methanofuran biosynthetic process	Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process.	got7fsn_ti	up-regulation of methanofuran biosynthesis|up regulation of methanofuran biosynthetic process|up-regulation of methanofuran biosynthetic process|activation of methanofuran biosynthetic process|up regulation of methanofuran biosynthesis|upregulation of methanofuran biosynthetic process|upregulation of methanofuran biosynthesis|activation of methanofuran biosynthesis|positive regulation of methanofuran biosynthesis						tt	2012-04-06T02:14:09Z						biological_process											owl:Class	
GO:0047359	biolink:NamedThing	1-alkenyl-2-acylglycerol choline phosphotransferase activity	Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.	got7fsn_ti	CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase activity|CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase activity											EC:2.7.8.22|MetaCyc:2.7.8.22-RXN|RHEA:21072		molecular_function											owl:Class	
GO:0102933	biolink:NamedThing	GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity	Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate.	got7fsn_ti												MetaCyc:RXN-8953|RHEA:36779|EC:2.6.1.102		molecular_function											owl:Class	
GO:0004676	biolink:NamedThing	3-phosphoinositide-dependent protein kinase activity	Phosphatidylinositol-3-phosphate-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	got7fsn_ti	phosphatidylinositol-3-phosphate protein kinase activity|PDK activity				This reaction requires the presence of a phosphatidylinositol-3-phosphate.							Reactome:R-HSA-437195		molecular_function											owl:Class	
GO:0030272	biolink:NamedThing	5-formyltetrahydrofolate cyclo-ligase activity	Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H(+) + phosphate.	got7fsn_ti	methenyl-THF synthetase activity|5,10-methenyltetrahydrofolate synthetase activity|5-formyltetrahydrofolate cyclodehydrase|5-Formyltetrahydrofolate cyclodehydrase activity|formyltetrahydrofolic cyclodehydrase activity|5-formyltetrahydrofolate cyclo-ligase (ADP-forming)										GO:0019006	EC:6.3.3.2|Reactome:R-HSA-6801342|KEGG_REACTION:R02301|RHEA:10488|MetaCyc:5-FORMYL-THF-CYCLO-LIGASE-RXN		molecular_function											owl:Class	
GO:0045209	biolink:NamedThing	MAPK phosphatase export from nucleus, leptomycin B sensitive	Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm.	got7fsn_ti	leptomycin B-sensitive MAPK phosphatase export out of nucleus|leptomycin B-sensitive MAPK phosphatase-nucleus export|leptomycin B-sensitive MAPK phosphatase transport from nucleus to cytoplasm|MAPK phosphatase transport from nucleus to cytoplasm, leptomycin B sensitive|MAPK phosphatase-nucleus export, leptomycin B sensitive|MAPK phosphatase export from cell nucleus, leptomycin B sensitive|MAPK phosphatase export out of nucleus, leptomycin B sensitive													biological_process											owl:Class	
GO:0000252	biolink:NamedThing	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity	Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.	got7fsn_ti	3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity|sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity|3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|C-3 sterol dehydrogenase (C-4 decarboxylase) activity|sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)|sterol 4alpha-carboxylic decarboxylase activity|3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|C-3 sterol dehydrogenase activity|3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)				Note that zymosterol is cholesta-8,24-dien-3-ol.							Reactome:R-HSA-194718|Reactome:R-HSA-194642|EC:1.1.1.170		molecular_function											owl:Class	
GO:0010768	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0102215	biolink:NamedThing	thiocyanate methyltransferase activity	Catalysis of the reaction: thiocyanate + S-adenosyl-L-methionine  <=> methyl thiocyanate + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:28014|MetaCyc:RXN-12189		molecular_function											owl:Class	
GO:0008904	biolink:NamedThing	hygromycin-B 7''-O-phosphotransferase activity	Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H(+).	got7fsn_ti	APH(7'') activity|hygromycin B kinase activity|destomic acid ring 7''-O-phosphotransferase activity|hygromycin-B kinase activity|hygromycin B phosphotransferase activity|ATP:hygromycin-B 7''-O-phosphotransferase activity											EC:2.7.1.119|MetaCyc:HYGROMYCIN-B-KINASE-RXN|RHEA:23388|KEGG_REACTION:R03770		molecular_function											owl:Class	
GO:0060270	biolink:NamedThing	main body follicle cell migration	The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte.	got7fsn_ti														biological_process											owl:Class	
GO:0050085	biolink:NamedThing	mannitol 2-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-mannitol + NADP(+) = D-fructose + H(+) + NADPH.	got7fsn_ti	D-mannitol:NADP+ 2-oxidoreductase activity|NADP-dependent mannitol dehydrogenase activity											RHEA:16765|MetaCyc:MANNITOL-2-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R00870|EC:1.1.1.138		molecular_function											owl:Class	
GO:0050693	biolink:NamedThing	LBD domain binding	Binding to a protein's ligand binding domain (LBD) domain, found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.	got7fsn_ti	ligand binding domain binding													molecular_function											owl:Class	
GO:0004307	biolink:NamedThing	ethanolaminephosphotransferase activity	Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.	got7fsn_ti	diacylglycerol ethanolaminephosphotransferase activity|CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity|phosphorylethanolamine-glyceride transferase activity|CDPethanolamine diglyceride phosphotransferase activity|EPT											MetaCyc:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN|EC:2.7.8.1|RHEA:32943|Reactome:R-HSA-1482962		molecular_function											owl:Class	
GO:0044573	biolink:NamedThing	nitrogenase P cluster assembly	The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide.	got7fsn_ti	nitrogenase P cluster maturation|nitrogenase P cluster biosynthesis						jl	2012-04-18T03:29:04Z						biological_process											owl:Class	
GO:0019134	biolink:NamedThing	glucosamine-1-phosphate N-acetyltransferase activity	Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+).	got7fsn_ti	acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase activity|acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase activity											EC:2.3.1.157|KEGG_REACTION:R05332|MetaCyc:2.3.1.157-RXN|RHEA:13725		molecular_function											owl:Class	
GO:0008489	biolink:NamedThing	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base.	got7fsn_ti	UDP-galactose glucosylceramide beta-1,4-galactosyltransferase activity|LacCer synthase activity|lactosylceramide synthase activity											MetaCyc:RXN-10764		molecular_function											owl:Class	
GO:0099130	biolink:NamedThing	estrogen binding	Binding to an estrogen.	got7fsn_ti														molecular_function											owl:Class	
GO:0102644	biolink:NamedThing	monocyclic sesterterpenediol synthase activity	Catalysis of the reaction: monocyclic sesterterpenediol <=> all-trans-geranylfarnesol + H2O.	got7fsn_ti												MetaCyc:RXN-15756		molecular_function											owl:Class	
GO:0032533	biolink:NamedThing	regulation of follicle cell microvillus length	A process that modulates the length of a microvillus on a follicle cell.	got7fsn_ti														biological_process											owl:Class	
GO:0018103	biolink:NamedThing	protein C-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.	got7fsn_ti	protein amino acid C-linked glycosylation											RESID:AA0217		biological_process											owl:Class	
GO:0031730	biolink:NamedThing	CCR5 chemokine receptor binding	Binding to a CCR5 chemokine receptor.	got7fsn_ti	CCR5 chemokine receptor ligand													molecular_function											owl:Class	
GO:0042858	biolink:NamedThing	chrysobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).	got7fsn_ti	chrysobactin biosynthetic process, peptide modification|chrysobactin biosynthesis|chrysobactin biosynthetic process, peptide formation|chrysobactin synthesis|chrysobactin anabolism|chrysobactin formation										GO:0031183|GO:0031184			biological_process											owl:Class	
GO:0034903	biolink:NamedThing	endosulfan ether monooxygenase activity	Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O.	got7fsn_ti												UM-BBD_reactionID:r1413		molecular_function											owl:Class	
GO:1990882	biolink:NamedThing	rRNA acetylation	The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti							al	2015-10-28T13:24:58Z						biological_process											owl:Class	
GO:0050445	biolink:NamedThing	asparagusate reductase activity	Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + H(+) + NADH.	got7fsn_ti	asparagusate reductase (NADH) activity|3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase activity|NADH:asparagusate oxidoreductase activity|asparagusic dehydrogenase activity|asparagusate reductase (NADH2)|asparagusate dehydrogenase activity|NADH2:asparagusate oxidoreductase activity											KEGG_REACTION:R03761|RHEA:14881|MetaCyc:ASPARAGUSATE-REDUCTASE-NADH-RXN|EC:1.8.1.11		molecular_function											owl:Class	
GO:0072707	biolink:NamedThing	cellular response to sodium dodecyl sulfate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.	got7fsn_ti	cellular response to SDS						mah	2012-04-11T03:35:15Z						biological_process											owl:Class	
GO:0034406	biolink:NamedThing	cell wall beta-glucan metabolic process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.	got7fsn_ti	cell wall beta-glucan metabolism													biological_process											owl:Class	
GO:0050353	biolink:NamedThing	trimethyllysine dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate.	got7fsn_ti	epsilon-trimethyllysine 2-oxoglutarate dioxygenase activity|TMLD activity|6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|trimethyllysine,2-oxoglutarate dioxygenase activity|TML hydroxylase activity|TML-alpha-ketoglutarate dioxygenase activity|TML dioxygenase activity|trimethyllysine alpha-ketoglutarate dioxygenase activity|N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)											KEGG_REACTION:R03451|RHEA:14181|EC:1.14.11.8|MetaCyc:TRIMETHYLLYSINE-DIOXYGENASE-RXN|Reactome:R-HSA-71241		molecular_function											owl:Class	
GO:0045975	biolink:NamedThing	positive regulation of translation, ncRNA-mediated	Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein.	got7fsn_ti	up regulation of mRNA translation, ncRNA-mediated|upregulation of mRNA translation, ncRNA-mediated|up-regulation of mRNA translation, ncRNA-mediated|activation of mRNA translation, ncRNA-mediated|stimulation of mRNA translation, ncRNA-mediated													biological_process											owl:Class	
GO:1990435	biolink:NamedThing	upper tip-link density	An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends.	got7fsn_ti	UTLD						sl	2014-07-30T16:36:32Z						cellular_component											owl:Class	
GO:0090204	biolink:NamedThing	protein localization to nuclear pore	A process in which a protein is transported to, or maintained in, a nuclear pore.	got7fsn_ti	protein localisation to nuclear pore						tb	2009-12-18T12:05:01Z						biological_process											owl:Class	
GO:0004322	biolink:NamedThing	ferroxidase activity	Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.	got7fsn_ti	HEPH|iron(II): oxygen oxidoreductase activity|caeruloplasmin|hephaestin|ceruloplasmin|ferroxidase, iron II:oxygen oxidoreductase activity|ferro:O2 oxidoreductase activity|Fe(II):oxygen oxidoreductase activity|ferroxidase I|multicopper ferroxidase iron transport mediator activity	https://github.com/geneontology/go-ontology/issues/20675										RHEA:11148|Reactome:R-HSA-1562603|Reactome:R-HSA-5621402|EC:1.16.3.1|Reactome:R-HSA-917891|MetaCyc:RXN0-1483|Reactome:R-HSA-917933|Reactome:R-HSA-1562604|Reactome:R-HSA-5691107|Reactome:R-HSA-1562626		molecular_function											owl:Class	
GO:0010048	biolink:NamedThing	vernalization response	The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures.	got7fsn_ti														biological_process											owl:Class	
GO:1990142	biolink:NamedThing	envenomation resulting in hemolysis in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with hemolysis in the bitten organism.	got7fsn_ti							sp	2013-07-18T10:46:03Z						biological_process											owl:Class	
GO:0008908	biolink:NamedThing	isochorismatase activity	Catalysis of the reaction: H(2)O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate.	got7fsn_ti	isochorismate pyruvate-hydrolase activity|2,3-dihydroxy-2,3-dihydrobenzoate synthase activity|2,3-dihydro-2,3-dihydroxybenzoate synthase activity|2,3 dihydro-2,3 dihydroxybenzoate synthase activity|2,3-dihydroxy-2,3-dihydrobenzoic synthase activity											KEGG_REACTION:R03037|RHEA:11112|EC:3.3.2.1|MetaCyc:ISOCHORMAT-RXN		molecular_function											owl:Class	
GO:1901510	biolink:NamedThing	(-)-microperfuranone metabolic process	The chemical reactions and pathways involving (-)-microperfuranone.	got7fsn_ti	(-)-microperfuranone metabolism						di	2012-10-18T06:54:10Z						biological_process											owl:Class	
GO:0060867	biolink:NamedThing	fruit abscission	The controlled shedding of a fruit.	got7fsn_ti							dph	2009-08-12T06:35:28Z						biological_process											owl:Class	
GO:0071820	biolink:NamedThing	N-box binding	Binding to an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses.	got7fsn_ti	N box binding|N-box promoter binding				Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		mah	2010-09-07T11:55:32Z						molecular_function											owl:Class	
GO:0004491	biolink:NamedThing	methylmalonate-semialdehyde dehydrogenase (acylating) activity	Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+.	got7fsn_ti	2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating)|MSDH activity|MMSA dehydrogenase activity											EC:1.2.1.27|MetaCyc:1.2.1.27-RXN|RHEA:20804|Reactome:R-HSA-70893		molecular_function											owl:Class	
GO:0015298	biolink:NamedThing	solute:cation antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out).	got7fsn_ti														molecular_function											owl:Class	
GO:0003386	biolink:NamedThing	amphid sensory organ development	The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.	got7fsn_ti							dph	2009-12-09T09:09:20Z						biological_process											owl:Class	
GO:0010179	biolink:NamedThing	IAA-Ala conjugate hydrolase activity	Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine.	got7fsn_ti												MetaCyc:RXN-2981		molecular_function											owl:Class	
GO:0090067	biolink:NamedThing	regulation of thalamus size	Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus.	got7fsn_ti							tb	2009-09-02T11:03:03Z						biological_process											owl:Class	
GO:0072174	biolink:NamedThing	metanephric tubule formation	The developmental process pertaining to the initial formation of a metanephric tubule.	got7fsn_ti							mah	2010-02-26T02:07:41Z						biological_process											owl:Class	
GO:0102339	biolink:NamedThing	3-oxo-arachidoyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA(4-) + NADP(3-) <=> 3-oxoicosanoyl-CoA + NADPH + H+.	got7fsn_ti												EC:1.1.1.330|MetaCyc:RXN-13298		molecular_function											owl:Class	
GO:0060001	biolink:NamedThing	minus-end directed microfilament motor activity	A motor activity that generates movement along a microfilament towards the minus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.	got7fsn_ti	minus-end directed actin filament motor activity|pointed-end directed actin-filament motor activity|minus-end directed actin-filament motor activity													molecular_function											owl:Class	
GO:0106355	biolink:NamedThing	4-hydroxybenzoate 3-monooxygenase [NADH] activity	Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + H2O + NAD+.	got7fsn_ti							hjd	2021-02-02T05:51:36Z				RHEA:19473		molecular_function											owl:Class	
GO:0004082	biolink:NamedThing	bisphosphoglycerate mutase activity	Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.	got7fsn_ti	DPGM|bisphosphoglyceromutase|3-phospho-D-glycerate 1,2-phosphomutase activity|2,3-bisphosphoglycerate mutase activity|BPGM activity|2,3-bisphosphoglycerate synthase activity|diphosphoglyceric mutase activity|bisphosphoglycerate synthase activity|biphosphoglycerate synthase activity|2,3-diphosphoglycerate mutase activity|diphosphoglycerate mutase activity|glycerate phosphomutase activity|diphosphoglyceromutase activity|2,3-diphosphoglyceromutase activity|2,3-diphosphoglycerate synthase activity											EC:5.4.2.4|MetaCyc:BISPHOSPHOGLYCERATE-MUTASE-RXN|Reactome:R-HSA-6798335|RHEA:17765		molecular_function											owl:Class	
GO:0048242	biolink:NamedThing	epinephrine secretion	The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.	got7fsn_ti	adrenaline secretion													biological_process											owl:Class	
GO:0050180	biolink:NamedThing	phloretin hydrolase activity	Catalysis of the reaction: H(2)O + phloretin = H(+) + phloretate + phloroglucinol.	got7fsn_ti	lactase-phlorizin hydrolase|2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase activity											MetaCyc:PHLORETIN-HYDROLASE-RXN|RHEA:23396|EC:3.7.1.4|KEGG_REACTION:R02901		molecular_function											owl:Class	
GO:0102943	biolink:NamedThing	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity	Catalysis of the reaction: (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid  = (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate.	got7fsn_ti												EC:5.3.3.17|MetaCyc:RXN-9031|RHEA:28182		molecular_function											owl:Class	
GO:0018896	biolink:NamedThing	dibenzothiophene catabolic process	The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.	got7fsn_ti	dibenzothiophene breakdown|dibenzothiophene catabolism|dibenzothiophene degradation											UM-BBD_pathwayID:dbt2		biological_process											owl:Class	
GO:0003856	biolink:NamedThing	3-dehydroquinate synthase activity	Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.	got7fsn_ti												RHEA:21968|MetaCyc:3-DEHYDROQUINATE-SYNTHASE-RXN|EC:4.2.3.4|KEGG_REACTION:R03083		molecular_function											owl:Class	
GO:0050847	biolink:NamedThing	progesterone receptor signaling pathway	Any series of molecular signals generated as a consequence of a progesterone binding to its receptor.	got7fsn_ti	progesterone receptor signalling pathway													biological_process											owl:Class	
GO:0102349	biolink:NamedThing	trans-lignocero-2-enoyl-CoA reductase activity	Catalysis of the reaction: tetracosanoyl-CoA + NADP <=> trans-2-tetracosenoyl-CoA + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13308		molecular_function											owl:Class	
GO:0034024	biolink:NamedThing	glutamate-putrescine ligase activity	Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate.	got7fsn_ti	YcjK|gamma-glutamylputrescine synthetase activity|L-glutamate:putrescine ligase (ADP-forming) activity											RHEA:13633|EC:6.3.1.11|MetaCyc:RXN0-3901|KEGG_REACTION:R07414		molecular_function											owl:Class	
GO:0098036	biolink:NamedThing	viral DNA genome packaging, 3' extended cos packaging	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends.	got7fsn_ti							bm	2012-07-20T11:38:40Z						biological_process											owl:Class	
GO:0050853	biolink:NamedThing	B cell receptor signaling pathway	A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.	got7fsn_ti	B-lymphocyte receptor signalling pathway|B cell receptor signalling pathway|B-cell receptor signaling pathway|B-lymphocyte receptor signaling pathway|B lymphocyte receptor signalling pathway|B-cell receptor signalling pathway|B lymphocyte receptor signaling pathway													biological_process											owl:Class	
GO:0008566	biolink:NamedThing	mitochondrial protein-transporting ATPase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.	got7fsn_ti	ATPase-coupled mitochondrial protein transporter activity				See also the cellular component term 'mitochondrial inner membrane presequence translocase complex ; GO:0005744'.							EC:7.4.2.3|MetaCyc:3.6.3.51-RXN		molecular_function											owl:Class	
GO:0070408	biolink:NamedThing	carbamoyl phosphate metabolic process	The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.	got7fsn_ti	carbamoyl phosphate metabolism											UM-BBD_pathwayID:bzn		biological_process											owl:Class	
GO:0071602	biolink:NamedThing	phytosphingosine biosynthetic process	The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.	got7fsn_ti	phytosphingosine biosynthesis|phytosphingosine synthesis|phytosphingosine anabolism|phytosphingosine formation						mah	2010-02-04T05:15:59Z						biological_process											owl:Class	
GO:0071284	biolink:NamedThing	cellular response to lead ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.	got7fsn_ti							mah	2009-12-10T04:00:41Z						biological_process											owl:Class	
GO:0061463	biolink:NamedThing	O-acetyl-ADP-ribose deacetylase activity	Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate.	got7fsn_ti							dph	2012-10-05T11:05:06Z						molecular_function											owl:Class	
GO:0070768	biolink:NamedThing	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).	got7fsn_ti	Snap25-Syt1-Unc13b-Vamp2-Stx1b2-Stx1a complex|SNARE complex (Snap25, Syt1, Unc13b, Vamp2, Stx1b2, Stx1a)						mah	2009-06-29T05:14:04Z						cellular_component											owl:Class	
GO:0034696	biolink:NamedThing	response to prostaglandin F	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.	got7fsn_ti	response to prostaglandin F stimulus													biological_process											owl:Class	
GO:0034733	biolink:NamedThing	transcription factor TFIIIB-beta complex	A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters.	got7fsn_ti					Note that the subunits of TFIIIB-beta are conserved between human and yeast; however, in yeast a single TFIIIB complex regulates transcription of tRNA, 5S rRNA and U6 snRNA genes, whereas two different TBP-dependent TFIIIB activities exist in humans.									cellular_component											owl:Class	
GO:0019678	biolink:NamedThing	propionate metabolic process, methylmalonyl pathway	The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway.	got7fsn_ti	propionate metabolism, methylmalonyl pathway											MetaCyc:PROPIONMET-PWY		biological_process											owl:Class	
GO:0080062	biolink:NamedThing	cytokinin 9-beta-glucosyltransferase activity	Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.	got7fsn_ti							dhl	2009-04-13T03:34:38Z				KEGG_REACTION:R08369		molecular_function											owl:Class	
GO:0047054	biolink:NamedThing	berbamunine synthase activity	Catalysis of the reaction: (S)-N-methylcoclaurine + (R)-N-methylcoclaurine + [reduced NADPH--hemoprotein reductase] + O2 <=> berbamunine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	got7fsn_ti	heme-thiolate	https://github.com/geneontology/go-ontology/issues/21133										EC:1.14.19.66|MetaCyc:1.1.3.34-RXN|RHEA:23576		molecular_function											owl:Class	
GO:0002006	biolink:NamedThing	vasoconstriction by vasopressin involved in systemic arterial blood pressure control	The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream.	got7fsn_ti	vasopressin mediated vasoconstriction involved in systemic arterial blood pressure control													biological_process											owl:Class	
GO:0047514	biolink:NamedThing	1,3-beta-D-glucan phosphorylase activity	Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.	got7fsn_ti	1,3-beta-D-glucan:orthophosphate glucosyltransferase activity|laminarin phosphorylase activity|1,3-beta-D-glucan:phosphate alpha-D-glucosyltransferase activity|laminarin phosphoryltransferase activity|1,3-beta-glucan phosphorylase activity											EC:2.4.1.97|MetaCyc:13-BETA-GLUCAN-PHOSPHORYLASE-RXN		molecular_function											owl:Class	
GO:0036078	biolink:NamedThing	minus-end specific microtubule depolymerization	The removal of tubulin heterodimers from the minus end of a microtubule.	got7fsn_ti							bf	2011-12-19T03:20:25Z						biological_process											owl:Class	
GO:0042184	biolink:NamedThing	xylene catabolic process	The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.	got7fsn_ti	xylene breakdown|xylene degradation|xylene catabolism													biological_process											owl:Class	
GO:0060371	biolink:NamedThing	regulation of atrial cardiac muscle cell membrane depolarization	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.	got7fsn_ti	regulation of atrial cardiomyocyte membrane depolarization|regulation of atrial cardiac muscle cell depolarization|electrocardiogram PR interval|atrial depolarization													biological_process											owl:Class	
GO:0103036	biolink:NamedThing	NADH:menaquinone oxidoreductase activity	Catalysis of the reaction: 5 H+ + NADH + a menaquinone <=> 4 H+ + NAD + a menaquinol.	got7fsn_ti												MetaCyc:RXN0-5388		molecular_function											owl:Class	
GO:0030647	biolink:NamedThing	aminoglycoside antibiotic metabolic process	The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.	got7fsn_ti	aminoglycoside antibiotic metabolism													biological_process											owl:Class	
GO:0045904	biolink:NamedThing	negative regulation of translational termination	Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.	got7fsn_ti	inhibition of translational termination|down-regulation of translational termination|downregulation of translational termination|down regulation of translational termination													biological_process											owl:Class	
GO:0004021	biolink:NamedThing	L-alanine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.	got7fsn_ti	L-alanine-alpha-ketoglutarate aminotransferase activity|ALT|pyruvate-alanine aminotransferase activity|glutamic--pyruvic transaminase activity|pyruvate-glutamate transaminase activity|glutamic-pyruvic aminotransferase activity|pyruvate transaminase activity|alanine-pyruvate aminotransferase activity|GPT|L-alanine transaminase activity|glutamic acid-pyruvic acid transaminase activity|glutamic--alanine transaminase activity|beta-alanine aminotransferase|alanine-alpha-ketoglutarate aminotransferase activity|alanine aminotransferase activity|alanine transaminase activity|L-alanine aminotransferase activity											Reactome:R-HSA-507749|Reactome:R-HSA-70524|KEGG_REACTION:R00258|Reactome:R-HSA-507775|EC:2.6.1.2|MetaCyc:ALANINE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-70523|RHEA:19453		molecular_function											owl:Class	
GO:0042731	biolink:NamedThing	PH domain binding	Binding to a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.	got7fsn_ti														molecular_function											owl:Class	
GO:0008569	biolink:NamedThing	minus-end-directed microtubule motor activity	A motor activity that generates movement along a microtubule toward the minus end, driven by ATP hydrolysis.	got7fsn_ti	dynein ATPase|ATP-dependent minus-end-directed microtubule motor activity|microtubule motor activity, minus-end-directed|kinesin ATP phosphohydrolase (minus-end-directed)|minus-end-directed kinesin ATPase activity|minus-end-directed ATP-dependent microtubule motor activity|ATP-dependent microtubule motor activity, minus-end-directed	https://github.com/geneontology/go-ontology/issues/21289|https://github.com/geneontology/go-ontology/issues/18664										MetaCyc:3.6.4.5-RXN|EC:5.6.1.2|EC:5.6.1.4		molecular_function											owl:Class	
GO:0031879	biolink:NamedThing	type 2 somatostatin receptor binding	Binding to a type 2 somatostatin receptor.	got7fsn_ti	type 2 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0103031	biolink:NamedThing	L-Ala-D/L-Glu epimerase activity	Catalysis of the reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate.	got7fsn_ti												MetaCyc:RXN0-5228|RHEA:28394		molecular_function											owl:Class	
GO:0008903	biolink:NamedThing	hydroxypyruvate isomerase activity	Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate.	got7fsn_ti	hydroxypyruvate ketol-isomerase activity|hydroxypyruvate aldose-ketose-isomerase activity											EC:5.3.1.22|KEGG_REACTION:R01394|RHEA:11952|MetaCyc:RXN0-305		molecular_function											owl:Class	
GO:0034545	biolink:NamedThing	fumarylpyruvate hydrolase activity	Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+.	got7fsn_ti												RHEA:26168|EC:3.7.1.20|UM-BBD_reactionID:r0811		molecular_function											owl:Class	
GO:0003873	biolink:NamedThing	6-phosphofructo-2-kinase activity	Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+).	got7fsn_ti	6-phosphofructo-2-kinase (phosphorylating)|ATP:D-fructose-6-phosphate 2-phosphotransferase activity|6-phosphofructose 2-kinase activity|fructose 6-phosphate 2-kinase activity|phosphofructokinase 2 activity|ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity											EC:2.7.1.105|Reactome:R-HSA-71802|KEGG_REACTION:R02732|MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN|RHEA:15653		molecular_function											owl:Class	
GO:0008650	biolink:NamedThing	rRNA (uridine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine.	got7fsn_ti												Reactome:R-HSA-6793127		molecular_function											owl:Class	
GO:0008701	biolink:NamedThing	4-hydroxy-2-oxovalerate aldolase activity	Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate.	got7fsn_ti	4-hydroxy-2-ketovalerate aldolase activity|DmpG|4-hydroxy-2-oxopentanoate pyruvate-lyase activity|HOA|4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) activity|4-hydroxy-2-oxovalerate pyruvate-lyase activity										GO:0018804	KEGG_REACTION:R00750|RHEA:22624|EC:4.1.3.39|UM-BBD_enzymeID:e0077|MetaCyc:MHPELY-RXN		molecular_function											owl:Class	
GO:0047748	biolink:NamedThing	cholestanetetraol 26-dehydrogenase activity	Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH.	got7fsn_ti	cholestanetetrol 26-dehydrogenase activity|5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase activity|5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol dehydrogenase activity|TEHC-NAD oxidoreductase activity											RHEA:34631|MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0140605	biolink:NamedThing	proton motive force-driven motor activity	A motor activity driven by an electrochemical proton gradient (proton-motive force). PMF-driven motors are used by bacterial flagella.	got7fsn_ti	proton motive force-driven motor activity	https://github.com/geneontology/go-ontology/issues/19590					pg	2021-02-17T08:04:50Z						molecular_function											owl:Class	
GO:0032222	biolink:NamedThing	regulation of synaptic transmission, cholinergic	Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.	got7fsn_ti														biological_process											owl:Class	
GO:0043804	biolink:NamedThing	imidazolone hydrolase activity	Catalysis of the reaction: N-formimidoylglycine => H2O + imidazol-4-one.	got7fsn_ti					Note that this reaction can occur spontaneously (see RHEA:24937).							RHEA:24935		molecular_function											owl:Class	
GO:0097375	biolink:NamedThing	spinal sensory neuron axon guidance	The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.	got7fsn_ti							pr	2012-10-01T10:17:20Z						biological_process											owl:Class	
GO:0099629	biolink:NamedThing	postsynaptic specialization of symmetric synapse	A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses.	got7fsn_ti	postsynaptic density of inhibitory synapse													cellular_component											owl:Class	
GO:0050156	biolink:NamedThing	ornithine N-benzoyltransferase activity	Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H(+).	got7fsn_ti	ornithine N-acyltransferase activity|benzoyl-CoA:L-ornithine N-benzoyltransferase activity											EC:2.3.1.127|KEGG_REACTION:R00664|RHEA:16929|MetaCyc:ORNITHINE-N-BENZOYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:1990400	biolink:NamedThing	mitochondrial ribosomal large subunit rRNA binding	Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA).	got7fsn_ti	mitochondrial LSU rRNA binding|21S rRNA binding				In S. cerevisiae, this is the mitochondrial 21S rRNA		mcc	2014-06-23T16:47:09Z						molecular_function											owl:Class	
GO:0071943	biolink:NamedThing	Myc-Max complex	A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max.	got7fsn_ti							mah	2010-10-01T11:56:17Z						cellular_component											owl:Class	
GO:0052055	biolink:NamedThing	modulation by symbiont of host molecular function	The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by symbiont of host protein function|modification by symbiont of host molecular function													biological_process											owl:Class	
GO:0120030	biolink:NamedThing	positive regulation of cilium beat frequency involved in ciliary motility	Any process that activates or increases the frequency of cilium beating involved in ciliary motility.	got7fsn_ti							krc	2017-04-19T14:32:16Z						biological_process											owl:Class	
GO:0070443	biolink:NamedThing	Mad-Max complex	A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.	got7fsn_ti														cellular_component											owl:Class	
GO:0047831	biolink:NamedThing	D-ornithine 4,5-aminomutase activity	Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate.	got7fsn_ti	D-alpha-ornithine 5,4-aminomutase activity|D-ornithine aminomutase activity											EC:5.4.3.5|RHEA:14893|KEGG_REACTION:R02461|MetaCyc:ORNMUTST-RXN		molecular_function											owl:Class	
GO:0102187	biolink:NamedThing	4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol dehydrogenase/C4-decarboxylase activity	Catalysis of the reaction: 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) <=> 4alpha,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3-one + NADH(2-) + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-11949		molecular_function											owl:Class	
GO:0034560	biolink:NamedThing	bisphenol A hydroxylase A activity	Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O.	got7fsn_ti												EC:1.14.13.-|UM-BBD_reactionID:r0861		molecular_function											owl:Class	
GO:0102859	biolink:NamedThing	1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming)	Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:1-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												EC:1.14.19.25|RHEA:46404|MetaCyc:RXN-8326		molecular_function											owl:Class	
GO:0034482	biolink:NamedThing	chondroitin 2-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.	got7fsn_ti	chondroitin 2-sulfotransferase activity|chondroitin 2-O-sulphotransferase activity													molecular_function											owl:Class	
GO:0044485	biolink:NamedThing	envenomation resulting in fibrinogenolysis in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism.	got7fsn_ti							jl	2012-01-26T03:41:01Z						biological_process											owl:Class	
GO:0019809	biolink:NamedThing	spermidine binding	Binding to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	got7fsn_ti														molecular_function											owl:Class	
GO:0019808	biolink:NamedThing	polyamine binding	Binding to a polyamine, an organic compound containing two or more amino groups.	got7fsn_ti														molecular_function											owl:Class	
GO:0097417	biolink:NamedThing	nematosome	Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles.	got7fsn_ti							pr	2012-11-06T16:47:56Z				NIF_Subcellular:sao138430598		cellular_component											owl:Class	
GO:0102714	biolink:NamedThing	gibberellin A12,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-6544		molecular_function											owl:Class	
GO:0086071	biolink:NamedThing	atrial cardiac muscle cell-AV node cell adhesion involved in cell communication	The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	got7fsn_ti	atrial cardiomyocyte-AV node cell adhesion involved in cell communication|atrial cardiomyocyte-atrioventricular node cell adhesion involved in cell communication						dph	2011-11-22T09:46:33Z						biological_process											owl:Class	
GO:0102202	biolink:NamedThing	soladodine glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + solasodine <=> UDP + solasodine 3-O-beta-D-glucopyranoside + H+.	got7fsn_ti												RHEA:61844|EC:2.4.1.173|MetaCyc:RXN-12123		molecular_function											owl:Class	
GO:0047511	biolink:NamedThing	(S)-methylmalonyl-CoA hydrolase activity	Catalysis of the reaction: (S)-methylmalonyl-CoA + H(2)O = CoA + H(+) + methylmalonate.	got7fsn_ti	D-methylmalonyl-coenzyme A hydrolase activity											KEGG_REACTION:R02764|EC:3.1.2.17|MetaCyc:S-METHYLMALONYL-COA-HYDROLASE-RXN|RHEA:17345		molecular_function											owl:Class	
GO:0061795	biolink:NamedThing	Golgi lumen acidification	Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion.	got7fsn_ti							dph	2016-10-05T08:42:40Z						biological_process											owl:Class	
GO:0035640	biolink:NamedThing	exploration behavior	The specific behavior of an organism in response to a novel environment or stimulus.	got7fsn_ti	exploratory behaviour|exploration behaviour|open-field behavior|exploratory behavior				For changes in locomotory behavior upon introduction to a novel environment, consider instead the child term: locomotory exploration behavior ; GO:0035641.		bf	2011-01-19T10:35:45Z						biological_process											owl:Class	
GO:0045231	biolink:NamedThing	slime layer organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.	got7fsn_ti	slime layer organization and biogenesis|slime layer organisation													biological_process											owl:Class	
GO:0046428	biolink:NamedThing	1,4-dihydroxy-2-naphthoate octaprenyltransferase activity	Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2.	got7fsn_ti	1,4-Dihydroxy-2-naphtoate prenyltransferase activity											RHEA:30099|MetaCyc:DMK-RXN|EC:2.5.1.74		molecular_function											owl:Class	
GO:0047320	biolink:NamedThing	D-4-hydroxyphenylglycine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate.	got7fsn_ti	D-hydroxyphenylglycine aminotransferase activity|D-4-hydroxyphenylglycine aminotransferase activity|D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase activity											EC:2.6.1.72|KEGG_REACTION:R04234|MetaCyc:2.6.1.72-RXN|RHEA:15589		molecular_function											owl:Class	
GO:0140641	biolink:NamedThing	mitotic spindle formation (spindle phase two)	The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase.	got7fsn_ti	metaphase spindle stability|metaphase spindle stabilization	https://github.com/geneontology/go-ontology/issues/21349					pg	2021-05-11T08:15:15Z						biological_process											owl:Class	
GO:0061565	biolink:NamedThing	dAMP phosphorylation	The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP.	got7fsn_ti							dph	2013-08-01T12:50:38Z						biological_process											owl:Class	
GO:0018905	biolink:NamedThing	dimethyl ether metabolic process	The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications.	got7fsn_ti	methyl ether metabolic process|methyl ether metabolism|dimethyl ether metabolism											UM-BBD_pathwayID:dme		biological_process											owl:Class	
GO:0033591	biolink:NamedThing	response to L-ascorbic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.	got7fsn_ti	response to L-ascorbate|response to ascorbic acid|response to vitamin C													biological_process											owl:Class	
GO:0071661	biolink:NamedThing	regulation of granzyme B production	Any process that modulates the frequency, rate, or extent of production of granzyme B.	got7fsn_ti							mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:0001817	biolink:NamedThing	regulation of cytokine production	Any process that modulates the frequency, rate, or extent of production of a cytokine.	got7fsn_ti	regulation of cytokine anabolism|regulation of cytokine formation|regulation of cytokine synthesis|regulation of cytokine biosynthetic process|regulation of cytokine secretion|regulation of cytokine biosynthesis										GO:0042035|GO:0050707			biological_process											owl:Class	
GO:0070530	biolink:NamedThing	K63-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0001940	biolink:NamedThing	male pronucleus	The pronucleus originating from the spermatozoa that was involved in fertilization.	got7fsn_ti														cellular_component											owl:Class	
GO:0047009	biolink:NamedThing	3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity	Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione.	got7fsn_ti	3alpha-hydroxy-5beta-steroid dehydrogenase activity|3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase activity|3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase activity|etiocholanolone 3alpha-dehydrogenase activity|etiocholanolone 3-alpha-dehydrogenase activity											EC:1.1.1.152|RHEA:10356|MetaCyc:1.1.1.152-RXN		molecular_function											owl:Class	
GO:0106300	biolink:NamedThing	protein-DNA covalent cross-linking repair	The removal of covalent cross-link between DNA and a protein.	got7fsn_ti	resolution of protein-DNA covalent cross-linking						hjd	2020-08-26T14:23:42Z						biological_process											owl:Class	
GO:0033737	biolink:NamedThing	1-pyrroline dehydrogenase activity	Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.	got7fsn_ti	ABALDH|YdcW|1-pyrroline:NAD+ oxidoreductase activity|gamma-aminobutyraldehyde dehydrogenase activity											MetaCyc:1.5.1.35-RXN|EC:1.2.1.19		molecular_function											owl:Class	
GO:0031471	biolink:NamedThing	ethanolamine degradation polyhedral organelle	An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase.	got7fsn_ti	ethanolamine metabolosome													cellular_component											owl:Class	
GO:0035785	biolink:NamedThing	cellular nickel ion homeostasis	Any process involved in the maintenance of an internal steady state of nickel ions at the level of a cell.	got7fsn_ti	cellular nickel homeostasis						bf	2011-04-05T09:55:56Z						biological_process											owl:Class	
GO:0016589	biolink:NamedThing	NURF complex	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.	got7fsn_ti	nucleosome remodeling factor complex													cellular_component											owl:Class	
GO:0031086	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay	A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.	got7fsn_ti	mRNA catabolism, deadenylation-independent decay|mRNA catabolic process, deadenylylation-independent|mRNA catabolic process, deadenylation-independent|mRNA catabolism, deadenylation-independent|mRNA catabolism, deadenylylation-independent|mRNA degradation, deadenylation-independent decay|mRNA breakdown, deadenylation-independent decay|nuclear mRNA catabolic process, deadenylation-independent decay|deadenylation-independent mRNA decay|deadenylylation-independent mRNA decay													biological_process											owl:Class	
GO:0044655	biolink:NamedThing	phagosome reneutralization	Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation.	got7fsn_ti	phagosomal reneutralization|phagosome pH elevation						jl	2012-07-26T04:21:14Z						biological_process											owl:Class	
GO:0051454	biolink:NamedThing	intracellular pH elevation	Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.	got7fsn_ti	cell pH elevation|intracellular alkalinization|pH elevation in cell|cellular alkalinization|elevation of cellular pH													biological_process											owl:Class	
GO:0009815	biolink:NamedThing	1-aminocyclopropane-1-carboxylate oxidase activity	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene.	got7fsn_ti	1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming)|ethene-forming enzyme|ACC oxidase activity|ethylene-forming enzyme|aminocyclopropanecarboxylate oxidase activity											KEGG_REACTION:R07214|EC:1.14.17.4|RHEA:23640|MetaCyc:ETHYL-RXN		molecular_function											owl:Class	
GO:0061576	biolink:NamedThing	acyl-CoA ceramide synthase complex	A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1.	got7fsn_ti							dph	2013-10-24T14:42:06Z						cellular_component											owl:Class	
GO:0071926	biolink:NamedThing	endocannabinoid signaling pathway	The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol.	got7fsn_ti	endocannabinoid signalling pathway						mah	2010-09-28T11:52:03Z						biological_process											owl:Class	
GO:0034390	biolink:NamedThing	smooth muscle cell apoptotic process	Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.	got7fsn_ti	programmed cell death of smooth muscle cells by apoptosis|apoptosis of smooth muscle cells|SMC apoptosis|smooth muscle cell programmed cell death by apoptosis|programmed cell death, smooth muscle cells|smooth muscle cell apoptosis													biological_process											owl:Class	
GO:0098997	biolink:NamedThing	fusion of virus membrane with host outer membrane	Fusion of a viral membrane with the host cell outer membrane during viral entry.	got7fsn_ti	viral envelope fusion|fusion of viral membrane with host outer membrane|viral-cell fusion molecule activity|viral penetration via membrane fusion|viral envelope fusion with host outer membrane											VZ:3941		biological_process											owl:Class	
GO:0102286	biolink:NamedThing	ornithine N-delta-acetyltransferase activity	Catalysis of the reaction: L-ornithinium(1+) = N(5)-acetyl-L-ornithine.	got7fsn_ti												MetaCyc:RXN-12667		molecular_function											owl:Class	
GO:0003939	biolink:NamedThing	L-iditol 2-dehydrogenase activity	Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+.	got7fsn_ti	sorbitol dehydrogenase activity|L-iditol:NAD oxidoreductase activity|NAD-dependent sorbitol dehydrogenase activity|glucitol dehydrogenase activity|NAD-sorbitol dehydrogenase|L-iditol (sorbitol) dehydrogenase activity|L-iditol:NAD+ 5-oxidoreductase activity|NAD+-dependent sorbitol dehydrogenase activity|polyol dehydrogenase activity				Note that enzymes with this activity also act on D-glucitol (giving D-fructose) and other closely related sugar alcohols.							MetaCyc:L-IDITOL-2-DEHYDROGENASE-RXN|EC:1.1.1.14|RHEA:10160|Reactome:R-HSA-5652195		molecular_function											owl:Class	
GO:0034013	biolink:NamedThing	aliphatic aldoxime dehydratase activity	Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O.	got7fsn_ti	OxdA|aliphatic aldoxime hydro-lyase (aliphatic-nitrile-forming) activity|aliphatic aldoxime hydro-lyase activity											EC:4.99.1.5|MetaCyc:4.99.1.5-RXN|RHEA:11316		molecular_function											owl:Class	
GO:0046576	biolink:NamedThing	rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity	Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue.	got7fsn_ti	rhamnogalacturonase B activity													molecular_function											owl:Class	
GO:0106073	biolink:NamedThing	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.	got7fsn_ti							hjd	2017-11-28T19:16:37Z				RHEA:29543|EC:2.4.1.256		molecular_function											owl:Class	
GO:0035711	biolink:NamedThing	T-helper 1 cell activation	The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	got7fsn_ti	Th1 cell activation						bf	2011-03-02T03:05:08Z						biological_process											owl:Class	
GO:0043422	biolink:NamedThing	protein kinase B binding	Binding to protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.	got7fsn_ti	Akt binding|PKB binding													molecular_function											owl:Class	
GO:1900815	biolink:NamedThing	monodictyphenone biosynthetic process	The chemical reactions and pathways resulting in the formation of monodictyphenone.	got7fsn_ti	monodictyphenone synthesis|monodictyphenone anabolism|monodictyphenone biosynthesis|monodictyphenone formation						di	2012-06-04T10:11:35Z						biological_process											owl:Class	
GO:0030341	biolink:NamedThing	chondroitin AC lyase activity	Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.	got7fsn_ti	chondroitin lyase activity|chondroitin AC eliminase activity|chondroitin sulfate lyase activity|chondroitinase AC|ChnAC|chondroitinase activity											EC:4.2.2.5|MetaCyc:4.2.2.5-RXN		molecular_function											owl:Class	
GO:0002158	biolink:NamedThing	osteoclast proliferation	The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes.	got7fsn_ti							hjd	2010-02-03T01:50:37Z						biological_process											owl:Class	
GO:2001028	biolink:NamedThing	positive regulation of endothelial cell chemotaxis	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.	got7fsn_ti							rl	2011-08-22T01:07:34Z						biological_process											owl:Class	
GO:0009088	biolink:NamedThing	threonine biosynthetic process	The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.	got7fsn_ti	threonine formation|threonine anabolism|threonine biosynthesis|threonine synthesis											MetaCyc:THRESYN-PWY|MetaCyc:HOMOSER-THRESYN-PWY		biological_process											owl:Class	
GO:0047227	biolink:NamedThing	indolylacetyl-myo-inositol galactosyltransferase activity	Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP.	got7fsn_ti	UDP-galactose:(indol-3-yl)acetyl-myo-inositol 5-O-D-galactosyltransferase activity|uridine diphosphogalactose-indolylacetylinositol galactosyltransferase activity|UDP-galactose:indol-3-ylacetyl-myo-inositol 5-O-D-galactosyltransferase activity|indol-3-ylacetyl-myo-inositol galactoside synthase activity											KEGG_REACTION:R04334|MetaCyc:2.4.1.156-RXN|EC:2.4.1.156|RHEA:21148		molecular_function											owl:Class	
GO:0047947	biolink:NamedThing	glutamine N-phenylacetyltransferase activity	Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.	got7fsn_ti	glutamine phenylacetyltransferase activity|phenylacetyl-CoA:L-glutamine N-acetyltransferase activity|phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase activity											MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN|EC:2.3.1.14|RHEA:21844		molecular_function											owl:Class	
GO:0016057	biolink:NamedThing	regulation of membrane potential in photoreceptor cell	Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon.	got7fsn_ti	changes in polarization state of photoreceptor cell membrane													biological_process											owl:Class	
GO:0052662	biolink:NamedThing	zeaxanthin epoxidase activity	Catalysis of the reaction:  all-trans-zeaxanthin + 4 H+ + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin].	got7fsn_ti	zeaxanthin epoxidase [overall] activity|antheraxanthin epoxidase activity|zea-epoxidase activity	https://github.com/geneontology/go-ontology/issues/21412			Multi-step reaction: RHEA:14937 and RHEA:24084. Formerly EC:1.14.13.90.						GO:0052663|GO:0009540	KEGG_REACTION:R07200|KEGG_REACTION:R06946|KEGG_REACTION:R06947|KEGG_REACTION:R07199|EC:1.14.15.21|RHEA:24084|MetaCyc:RXN-7978|MetaCyc:RXN-7979		molecular_function											owl:Class	
GO:0039521	biolink:NamedThing	suppression by virus of host autophagy	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host.	got7fsn_ti	inhibition by virus of host autophagy|negative regulation by virus of host autophagy|inhibition of host autophagy by virus						bf	2011-06-22T04:30:11Z				VZ:845		biological_process											owl:Class	
GO:0019010	biolink:NamedThing	farnesoic acid O-methyltransferase activity	Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine.	got7fsn_ti	S-adenosyl-methionine:farnesoic acid O-methyltransferase activity													molecular_function											owl:Class	
GO:0035520	biolink:NamedThing	monoubiquitinated protein deubiquitination	The removal of the ubiquitin group from a monoubiquitinated protein.	got7fsn_ti	monoubiquitinated protein deubiquitinylation|monoubiquitinated protein deubiquitylation						bf	2010-05-04T04:28:38Z						biological_process											owl:Class	
GO:0047449	biolink:NamedThing	2-dehydro-3-deoxy-L-arabinonate dehydratase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O.	got7fsn_ti	2-dehydro-3-deoxy-L-arabinonate hydro-lyase activity|2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)|2-keto-3-deoxy-L-arabinonate dehydratase activity											EC:4.2.1.43|KEGG_REACTION:R02278|MetaCyc:4.2.1.43-RXN|RHEA:17201		molecular_function											owl:Class	
GO:0098001	biolink:NamedThing	receptor-mediated bacteriophage reversible attachment to host cell	Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection.	got7fsn_ti	phage reversible adsorption|reversible bacteriophage attachment, binding of host cell surface receptor				This process was historically defined by the release, by Waring blending or sonication, by dilution and centrifugation, or by filtration and washing, of infective virions from their complexes with cells, thus contrary to what is observed after irreversible adsorption.		bm							biological_process											owl:Class	
GO:0016153	biolink:NamedThing	urocanate hydratase activity	Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O.	got7fsn_ti	3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming)|3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase activity|imidazolonepropionate hydrolase activity|urocanase activity											KEGG_REACTION:R02914|Reactome:R-HSA-70903|RHEA:13101|MetaCyc:UROCANATE-HYDRATASE-RXN|EC:4.2.1.49		molecular_function											owl:Class	
GO:0050060	biolink:NamedThing	long-chain-alcohol dehydrogenase activity	Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH.	got7fsn_ti	fatty alcohol oxidoreductase activity|long-chain-alcohol:NAD+ oxidoreductase activity|long-chain alcohol dehydrogenase activity											RHEA:17977|EC:1.1.1.192|MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0071196	biolink:NamedThing	Kv4.3-KChIP1 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.	got7fsn_ti							mah	2009-11-23T04:59:38Z				CORUM:3091		cellular_component											owl:Class	
GO:0016270	biolink:NamedThing	O-glycan processing, core 4	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.	got7fsn_ti														biological_process											owl:Class	
GO:0098592	biolink:NamedThing	cytoplasmic side of apical plasma membrane	The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.	got7fsn_ti							dos	2014-03-06T12:07:32Z						cellular_component											owl:Class	
GO:0031880	biolink:NamedThing	type 3 somatostatin receptor binding	Binding to a type 3 somatostatin receptor.	got7fsn_ti	type 3 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0070058	biolink:NamedThing	tRNA gene clustering	The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.	got7fsn_ti														biological_process											owl:Class	
GO:0019854	biolink:NamedThing	L-ascorbic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.	got7fsn_ti	L-ascorbic acid breakdown|vitamin C catabolic process|ascorbate catabolic process|L-ascorbic acid catabolism|L-ascorbic acid degradation|vitamin C catabolism|ascorbate catabolism											MetaCyc:PWY0-301		biological_process											owl:Class	
GO:0052578	biolink:NamedThing	alpha-farnesene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate.	got7fsn_ti	(E,E)-alpha-farnesene synthase activity						ai	2010-08-09T01:39:42Z				MetaCyc:RXN-8574|RHEA:27421		molecular_function											owl:Class	
GO:0004420	biolink:NamedThing	hydroxymethylglutaryl-CoA reductase (NADPH) activity	Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH.	got7fsn_ti	HMG-CoA reductase activity|3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|hydroxymethylglutaryl-CoA reductase activity	https://github.com/geneontology/go-ontology/issues/21411									GO:0042282	Reactome:R-HSA-191352|KEGG_REACTION:R02082|EC:1.1.1.34|RHEA:15989|MetaCyc:1.1.1.34-RXN		molecular_function											owl:Class	
GO:0003938	biolink:NamedThing	IMP dehydrogenase activity	Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.	got7fsn_ti	IMP oxidoreductase activity|inosine monophosphate dehydrogenase activity|inosine 5'-monophosphate dehydrogenase activity|inosinic acid dehydrogenase activity|IMP:NAD+ oxidoreductase activity|inosinate dehydrogenase activity|inosine monophosphate oxidoreductase activity|inosine-5'-phosphate dehydrogenase activity											EC:1.1.1.205|MetaCyc:IMP-DEHYDROG-RXN|Reactome:R-HSA-73794|RHEA:11708		molecular_function											owl:Class	
GO:0034281	biolink:NamedThing	ent-isokaurene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0002952	biolink:NamedThing	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione.	got7fsn_ti	phospho-AI-2 isomerase activity													molecular_function											owl:Class	
GO:0021975	biolink:NamedThing	pons reticulospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.	got7fsn_ti														biological_process											owl:Class	
GO:0030941	biolink:NamedThing	chloroplast targeting sequence binding	Binding to a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast.	got7fsn_ti														molecular_function											owl:Class	
GO:0032142	biolink:NamedThing	single guanine insertion binding	Binding to a double-stranded DNA region containing a single guanine insertion or a deletion that results in an unpaired guanine.	got7fsn_ti														molecular_function											owl:Class	
GO:0097317	biolink:NamedThing	invasive growth in response to biotic stimulus	The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus.	got7fsn_ti							pr	2012-05-31T10:38:16Z						biological_process											owl:Class	
GO:0070850	biolink:NamedThing	TACC/TOG complex	A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.	got7fsn_ti							mah	2009-08-05T03:06:08Z						cellular_component											owl:Class	
GO:1900719	biolink:NamedThing	regulation of uterine smooth muscle relaxation	Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation.	got7fsn_ti	regulation of smooth muscle relaxation of the uterus						jl	2012-05-24T03:12:26Z						biological_process											owl:Class	
GO:0021858	biolink:NamedThing	GABAergic neuron differentiation in basal ganglia	The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron.	got7fsn_ti														biological_process											owl:Class	
GO:0018701	biolink:NamedThing	2,5-dichlorohydroquinone reductive dehalogenase activity	Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone).	got7fsn_ti												EC:1.97.1.-|UM-BBD_enzymeID:e0366		molecular_function											owl:Class	
GO:1990412	biolink:NamedThing	hercynylselenocysteine lyase activity (selenoneine-forming)	Catalysis of the reaction: hercynylselenocysteine + 2H+ = selenoneine + pyruvate + ammonium.	got7fsn_ti							mah	2014-07-02T15:51:07Z				RHEA:42696		molecular_function											owl:Class	
GO:0006532	biolink:NamedThing	aspartate biosynthetic process	The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.	got7fsn_ti	aspartate biosynthesis|aspartate anabolism|aspartate formation|aspartate synthesis													biological_process											owl:Class	
GO:0050629	biolink:NamedThing	tetrachloroethene reductive dehalogenase activity	Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor.	got7fsn_ti	tetrachloroethene reductase activity|acceptor:trichloroethene oxidoreductase (chlorinating)											MetaCyc:1.97.1.8-RXN|RHEA:20353|EC:1.21.99.5		molecular_function											owl:Class	
GO:0061367	biolink:NamedThing	behavioral response to acetic acid induced pain	Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.	got7fsn_ti							dph	2010-10-21T03:26:31Z						biological_process											owl:Class	
GO:0033838	biolink:NamedThing	flavonol-3-O-glucoside glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside.	got7fsn_ti	UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase activity											EC:2.4.1.239|RHEA:18893|MetaCyc:2.4.1.239-RXN		molecular_function											owl:Class	
GO:0103067	biolink:NamedThing	4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity	Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H.	got7fsn_ti												RHEA:33447|EC:1.1.1.170|MetaCyc:RXN66-23		molecular_function											owl:Class	
GO:1900801	biolink:NamedThing	cspyrone B1 catabolic process	The chemical reactions and pathways resulting in the breakdown of cspyrone B1.	got7fsn_ti	cspyrone B1 breakdown|cspyrone B1 catabolism|cspyrone B1 degradation						di	2012-06-04T09:50:58Z						biological_process											owl:Class	
GO:0019283	biolink:NamedThing	L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine.	got7fsn_ti	L-methionine anabolism from O-phospho-L-homoserine and cystathionine|L-methionine formation from O-phospho-L-homoserine and cystathionine|L-methionine synthesis from O-phospho-L-homoserine and cystathionine|methionine biosynthetic process from O-phospho-L-homoserine and cystathionine													biological_process											owl:Class	
GO:0070220	biolink:NamedThing	aerobic sulfur oxidation	A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.	got7fsn_ti	aerobic sulphur oxidation											MetaCyc:SULFUROX-PWY		biological_process											owl:Class	
GO:0030589	biolink:NamedThing	pseudocleavage involved in syncytial blastoderm formation	Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	pseudocleavage during syncytial blastoderm formation													biological_process											owl:Class	
GO:0033391	biolink:NamedThing	chromatoid body	A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).	got7fsn_ti														cellular_component											owl:Class	
GO:0046197	biolink:NamedThing	orcinol biosynthetic process	The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.	got7fsn_ti	orcinol formation|orcinol biosynthesis|orcinol anabolism|orcinol synthesis													biological_process											owl:Class	
GO:0001198	biolink:NamedThing	negative regulation of mating-type specific transcription from RNA polymerase II promoter	Any mating-type specific process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.	got7fsn_ti	down regulation of RNA polymerase II transcription, mating-type specific|down-regulation of RNA polymerase II transcription, mating-type specific|inhibition of RNA polymerase II transcription, mating-type specific|downregulation of RNA polymerase II transcription, mating-type specific						krc	2011-11-23T09:36:06Z						biological_process											owl:Class	
GO:0070579	biolink:NamedThing	methylcytosine dioxygenase activity	Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2.	got7fsn_ti							mah	2009-04-22T02:29:41Z				Reactome:R-HSA-5221014|Reactome:R-HSA-5220952|Reactome:R-HSA-5220990		molecular_function											owl:Class	
GO:0004347	biolink:NamedThing	glucose-6-phosphate isomerase activity	Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.	got7fsn_ti	phosphohexoisomerase activity|D-glucose-6-phosphate ketol-isomerase activity|phosphohexose isomerase activity|glucose phosphate isomerase activity|hexose monophosphate isomerase activity|phosphosaccharomutase activity|oxoisomerase activity|hexosephosphate isomerase activity|phosphohexomutase activity|phosphoglucoisomerase activity|D-glucose-6-phosphate aldose-ketose-isomerase activity|phosphoglucose isomerase activity|hexose phosphate isomerase activity											RHEA:11816|Reactome:R-HSA-70471|Reactome:R-HSA-70475|EC:5.3.1.9|MetaCyc:PGLUCISOM-RXN		molecular_function											owl:Class	
GO:0032399	biolink:NamedThing	HECT domain binding	Binding to a HECT, 'Homologous to the E6-AP Carboxy-Terminus', domain of a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0008831	biolink:NamedThing	dTDP-4-dehydrorhamnose reductase activity	Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH.	got7fsn_ti	dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase activity|dTDP-4-keto-L-rhamnose reductase activity|thymidine diphospho-4-ketorhamnose reductase activity|dTDP-4-ketorhamnose reductase activity|dTDP-6-deoxy-L-mannose dehydrogenase activity|TDP-4-keto-rhamnose reductase activity|reductase, thymidine diphospho-4-ketorhamnose											MetaCyc:DTDPDEHYRHAMREDUCT-RXN|EC:1.1.1.133|KEGG_REACTION:R02777|RHEA:21796		molecular_function											owl:Class	
GO:0045521	biolink:NamedThing	interleukin-25 receptor binding	Binding to an interleukin-25 receptor.	got7fsn_ti	interleukin-25 receptor ligand|IL-25													molecular_function											owl:Class	
GO:0060793	biolink:NamedThing	sweat gland placode formation	The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.	got7fsn_ti							dph	2009-08-04T12:38:10Z						biological_process											owl:Class	
GO:0033457	biolink:NamedThing	GAU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GAU codon.	got7fsn_ti	GAT codon-amino acid adaptor activity|aspartic acid tRNA				Note that in the standard genetic code, GAT codes for aspartic acid.									molecular_function											owl:Class	
GO:1900817	biolink:NamedThing	ochratoxin A catabolic process	The chemical reactions and pathways resulting in the breakdown of ochratoxin A.	got7fsn_ti	Ochratoxin A breakdown|Ochratoxin A degradation|ochratoxin A degradation|Ochratoxin A catabolic process|ochratoxin A breakdown|ochratoxin A catabolism|Ochratoxin A catabolism						di	2012-06-04T10:13:26Z						biological_process											owl:Class	
GO:0034268	biolink:NamedThing	discadenine biosynthetic process	The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.	got7fsn_ti	discadenine biosynthesis|discadenine formation|discadenine anabolism|discadenine synthesis													biological_process											owl:Class	
GO:0090560	biolink:NamedThing	2-(3-amino-3-carboxypropyl)histidine synthase activity	Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].	got7fsn_ti							tb	2014-03-27T14:58:50Z				RHEA:36783|Reactome:R-HSA-5358494|MetaCyc:RXN-11371		molecular_function											owl:Class	
GO:0010540	biolink:NamedThing	basipetal auxin transport	The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root.	got7fsn_ti														biological_process											owl:Class	
GO:0103042	biolink:NamedThing	4-hydroxy-L-threonine aldolase activity	Catalysis of the reaction: 4-hydroxy-L-threonine <=> glycolaldehyde + glycine.	got7fsn_ti												RHEA:28779|MetaCyc:RXN0-6563		molecular_function											owl:Class	
GO:0047819	biolink:NamedThing	D-glutamate(D-aspartate) oxidase activity	Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.	got7fsn_ti	D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)|D-glutamic-aspartic oxidase activity|D-monoaminodicarboxylic acid oxidase activity				For the individual reactions, see instead 'D-glutamate oxidase activity ;GO:0047821' and 'D-aspartate oxidase activity ; GO:0008445'.							EC:1.4.3.15|MetaCyc:D-GLUTAMATED-ASPARTATE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0047335	biolink:NamedThing	3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity	Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate.	got7fsn_ti	1,3-diphosphoglycerate-polyphosphate phosphotransferase activity|diphosphoglycerate-polyphosphate phosphotransferase activity|3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase activity											RHEA:18665|MetaCyc:2.7.4.17-RXN|EC:2.7.4.17		molecular_function											owl:Class	
GO:0044088	biolink:NamedThing	regulation of vacuole organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.	got7fsn_ti	regulation of vacuole organisation|regulation of vacuole biogenesis													biological_process											owl:Class	
GO:0016258	biolink:NamedThing	N-glycan diversification	The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases.	got7fsn_ti														biological_process											owl:Class	
GO:0008070	biolink:NamedThing	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded	Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line.	got7fsn_ti	maternal determination of dorsal-ventral axis, ovarian follicular epithelium, germ-line encoded|maternal determination of dorsoventral axis, ovarian follicular epithelium, germ-line encoded													biological_process											owl:Class	
GO:0062050	biolink:NamedThing	GPI-mannose ethanolamine phosphate phosphodiesterase activity	A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor.	got7fsn_ti							dph	2018-06-01T18:26:54Z						molecular_function											owl:Class	
GO:0050569	biolink:NamedThing	glycolaldehyde dehydrogenase activity	Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH.	got7fsn_ti	glycol aldehyde dehydrogenase activity|glycolaldehyde:NAD+ oxidoreductase activity											EC:1.2.1.21|RHEA:20001|MetaCyc:GLYCOLALD-DEHYDROG-RXN|KEGG_REACTION:R01333		molecular_function											owl:Class	
GO:0061481	biolink:NamedThing	response to TNF agonist	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus.	got7fsn_ti							dph	2012-11-07T09:14:07Z						biological_process											owl:Class	
GO:0036485	biolink:NamedThing	dorsolateral trunk neural crest cell migration	The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells.	got7fsn_ti	dorsolateral trunk NCC migration						bf	2014-08-26T15:29:04Z						biological_process											owl:Class	
GO:0033504	biolink:NamedThing	floor plate development	The progression of the floor plate over time from its initial formation until its mature state.	got7fsn_ti														biological_process											owl:Class	
GO:0046280	biolink:NamedThing	chalcone catabolic process	The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives.	got7fsn_ti	chalcone breakdown|chalcone catabolism|chalcone degradation													biological_process											owl:Class	
GO:0046271	biolink:NamedThing	phenylpropanoid catabolic process	The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid.	got7fsn_ti	phenylpropanoid degradation|phenylpropanoid catabolism|phenylpropanoid breakdown													biological_process											owl:Class	
GO:0075279	biolink:NamedThing	uredinium development	The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.	got7fsn_ti	development of uredium													biological_process											owl:Class	
GO:0030084	biolink:NamedThing	PSI associated light-harvesting complex I, LHCIb subcomplex	A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm.	got7fsn_ti														cellular_component											owl:Class	
GO:0033908	biolink:NamedThing	beta-L-rhamnosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides.	got7fsn_ti	beta-L-rhamnoside rhamnohydrolase activity											MetaCyc:3.2.1.43-RXN|EC:3.2.1.43		molecular_function											owl:Class	
GO:0008847	biolink:NamedThing	Enterobacter ribonuclease activity	Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.	got7fsn_ti	Enterobacter RNase activity|enterobacter ribonuclease activity											EC:4.6.1.21|MetaCyc:3.1.27.6-RXN		molecular_function											owl:Class	
GO:0010430	biolink:NamedThing	fatty acid omega-oxidation	A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.	got7fsn_ti												MetaCyc:PWY-2724		biological_process											owl:Class	
GO:0051274	biolink:NamedThing	beta-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucans.	got7fsn_ti	beta-glucan synthesis|beta-glucan formation|beta-glucan biosynthesis|beta-glucan anabolism													biological_process											owl:Class	
GO:0030927	biolink:NamedThing	manganese incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide	The incorporation of manganese into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site.	got7fsn_ti												RESID:AA0366		biological_process											owl:Class	
GO:0009836	biolink:NamedThing	fruit ripening, climacteric	A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset.	got7fsn_ti														biological_process											owl:Class	
GO:0120239	biolink:NamedThing	vascular endothelial glycocalyx	The carbohydrate-rich layer lining the vascular endothelium connected to the endothelium through a variety of molecules, mainly proteoglycans and glycoproteins. These form a network in which soluble molecules, either plasma- or endothelium-derived, are incorporated.	got7fsn_ti	endothelial glycocalyx	https://github.com/geneontology/go-ontology/issues/19782					krc	2020-07-27T21:55:41Z						cellular_component											owl:Class	
GO:0006438	biolink:NamedThing	valyl-tRNA aminoacylation	The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0044815	biolink:NamedThing	DNA packaging complex	A protein complex that plays a role in the process of DNA packaging.	got7fsn_ti							jl	2013-09-19T11:33:45Z						cellular_component											owl:Class	
GO:0018621	biolink:NamedThing	4-sulfobenzoate 3,4-dioxygenase activity	Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite.	got7fsn_ti	4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming)|4-sulfobenzoate 3,4-dioxygenase system|4-sulfobenzoate dioxygenase activity|4-sulphobenzoate 3,4-dioxygenase activity											EC:1.14.12.8|KEGG_REACTION:R01636|UM-BBD_reactionID:r0293|MetaCyc:4-SULFOBENZOATE-34-DIOXYGENASE-RXN|RHEA:13937		molecular_function											owl:Class	
GO:0000171	biolink:NamedThing	ribonuclease MRP activity	Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA.	got7fsn_ti	RNase MRP											Wikipedia:RNase_MRP		molecular_function											owl:Class	
GO:0042767	biolink:NamedThing	ecdysteroid 22-hydroxylase activity	Catalysis of the hydroxylation of an ecdysteroid at carbon position 22.	got7fsn_ti					Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22-dideoxyecdysone (ketotriol) to 2-deoxyecdysone.									molecular_function											owl:Class	
GO:0004062	biolink:NamedThing	aryl sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.	got7fsn_ti	phenol sulfokinase activity|phenol sulfotransferase activity|p-nitrophenol sulfotransferase activity|dopamine sulfotransferase activity|arylsulfotransferase|sulfokinase activity|aryl sulphotransferase activity|4-nitrocatechol sulfokinase activity|1-naphthol phenol sulfotransferase activity|PST|ritodrine sulfotransferase activity|2-naphtholsulfotransferase activity|3'-phosphoadenylyl-sulfate:phenol sulfotransferase activity											Reactome:R-HSA-158860|Reactome:R-HSA-158849|MetaCyc:ARYL-SULFOTRANSFERASE-RXN|Reactome:R-HSA-176585|EC:2.8.2.1|RHEA:12164|Reactome:R-HSA-159358|Reactome:R-HSA-158468|Reactome:R-HSA-176646|Reactome:R-HSA-176474		molecular_function											owl:Class	
GO:0045029	biolink:NamedThing	G protein-coupled UDP receptor activity	Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP.	got7fsn_ti	UDP-activated nucleotide receptor activity													molecular_function											owl:Class	
GO:0050387	biolink:NamedThing	urethanase activity	Catalysis of the reaction: H(2)O + H(+) + urethane = CO(2) + ethanol + NH(4)(+).	got7fsn_ti	urethane hydrolase activity|urethane amidohydrolase (decarboxylating)											RHEA:21372|MetaCyc:URETHANASE-RXN|EC:3.5.1.75|KEGG_REACTION:R02359		molecular_function											owl:Class	
GO:0002409	biolink:NamedThing	Langerhans cell chemotaxis	The movement of a Langerhans cell in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0033192	biolink:NamedThing	calmodulin-dependent protein phosphatase activity	Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.	got7fsn_ti	Ca2+/CaM-dependent protein phosphatase activity|calcineurin activity|calcium- and calmodulin-dependent protein phosphatase activity|calcium/calmodulin-dependent protein phosphatase activity											Reactome:R-HSA-4551451|Reactome:R-HSA-2730849		molecular_function											owl:Class	
GO:0034988	biolink:NamedThing	Fc-gamma receptor I complex binding	Binding to one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.	got7fsn_ti														molecular_function											owl:Class	
GO:0052794	biolink:NamedThing	exo-alpha-(2->3)-sialidase activity	Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates.	got7fsn_ti	exo-alpha-(2,3)-sialidase activity|exo-alpha-2,3-sialidase activity											EC:3.2.1.18		molecular_function											owl:Class	
GO:0035133	biolink:NamedThing	post-embryonic caudal fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.	got7fsn_ti														biological_process											owl:Class	
GO:0050914	biolink:NamedThing	sensory perception of salty taste	The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	got7fsn_ti	salty taste perception													biological_process											owl:Class	
GO:0102444	biolink:NamedThing	isorhamnetin 3-O-methyltransferase activity	Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine  <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13929		molecular_function											owl:Class	
GO:0044090	biolink:NamedThing	positive regulation of vacuole organization	Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.	got7fsn_ti	positive regulation of vacuole biogenesis|positive regulation of vacuole organisation													biological_process											owl:Class	
GO:0007298	biolink:NamedThing	border follicle cell migration	The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.	got7fsn_ti	border cell migration													biological_process											owl:Class	
GO:2000047	biolink:NamedThing	regulation of cell-cell adhesion mediated by cadherin	Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin.	got7fsn_ti							jl	2010-08-20T12:56:44Z						biological_process											owl:Class	
GO:0047037	biolink:NamedThing	salutaridine reductase (NADPH) activity	Catalysis of the reaction: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine.	got7fsn_ti	salutaridinol:NADP+ 7-oxidoreductase activity											KEGG_REACTION:R04697|MetaCyc:1.1.1.248-RXN|EC:1.1.1.248|RHEA:10108		molecular_function											owl:Class	
GO:1903304	biolink:NamedThing	positive regulation of pyruvate kinase activity	Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity.	got7fsn_ti	positive regulation of phosphoenol transphosphorylase activity|up-regulation of phosphoenolpyruvate kinase activity|up-regulation of pyruvate kinase activity|upregulation of pyruvate kinase activity|up-regulation of ATP:pyruvate 2-O-phosphotransferase activity|upregulation of phosphoenolpyruvate kinase activity|activation of ATP:pyruvate 2-O-phosphotransferase activity|upregulation of ATP:pyruvate 2-O-phosphotransferase activity|activation of phosphoenolpyruvate kinase activity|activation of phosphoenol transphosphorylase activity|up regulation of phosphoenolpyruvate kinase activity|positive regulation of ATP:pyruvate 2-O-phosphotransferase activity|up regulation of phosphoenol transphosphorylase activity|up regulation of ATP:pyruvate 2-O-phosphotransferase activity|up regulation of pyruvate kinase activity|upregulation of phosphoenol transphosphorylase activity|activation of pyruvate kinase activity|positive regulation of phosphoenolpyruvate kinase activity|up-regulation of phosphoenol transphosphorylase activity						mr	2014-08-15T23:26:06Z						biological_process											owl:Class	
GO:0051347	biolink:NamedThing	positive regulation of transferase activity	Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.	got7fsn_ti	upregulation of transferase activity|up-regulation of transferase activity|stimulation of transferase activity|transferase activator|up regulation of transferase activity|activation of transferase activity				This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.									biological_process											owl:Class	
GO:0032638	biolink:NamedThing	interleukin-9 production	The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-9 biosynthetic process|IL-9 production|interleukin-9 secretion										GO:0042229|GO:0072607			biological_process											owl:Class	
GO:0047993	biolink:NamedThing	hydroxymalonate dehydrogenase activity	Catalysis of the reaction: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate.	got7fsn_ti	hydroxymalonate:NAD+ oxidoreductase activity											EC:1.1.1.167|KEGG_REACTION:R02969|MetaCyc:HYDROXYMALONATE-DEHYDROGENASE-RXN|RHEA:11284		molecular_function											owl:Class	
GO:0050035	biolink:NamedThing	L-sorbose oxidase activity	Catalysis of the reaction: L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2).	got7fsn_ti	L-sorbose:oxygen 5-oxidoreductase activity											RHEA:17853|KEGG_REACTION:R01695|EC:1.1.3.11|MetaCyc:L-SORBOSE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0035837	biolink:NamedThing	ergot alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of an ergot alkaloid.	got7fsn_ti	ergot alkaloid formation|ergot alkaloid biosynthesis|ergot alkaloid anabolism|ergot alkaloid synthesis						bf	2011-05-04T03:23:57Z						biological_process											owl:Class	
GO:0008934	biolink:NamedThing	inositol monophosphate 1-phosphatase activity	Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.	got7fsn_ti	myo-inositol-1-phosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity|L-myo-inositol-1-phosphate phosphatase activity|myo-inositol 1-phosphatase activity|inositol 1-phosphatase activity|inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-monophosphatase activity											MetaCyc:RXN0-5408|RHEA:27670|EC:3.1.3.25|Reactome:R-HSA-1855154		molecular_function											owl:Class	
GO:0044155	biolink:NamedThing	host caveola	A small pit, depression, or invagination, such as any of the minute pits or incuppings of the host cell membrane formed during pinocytosis, that communicates with the outside of a host cell and extends inward, indenting the host cytoplasm and the host cell membrane. Such caveolae may be pinched off to form free vesicles within the host cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							jl	2009-08-11T04:00:55Z						cellular_component											owl:Class	
GO:0002277	biolink:NamedThing	myeloid dendritic cell activation involved in immune response	The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	myeloid dendritic cell activation during immune response													biological_process											owl:Class	
GO:0050534	biolink:NamedThing	3-deoxyoctulosonase activity	Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.	got7fsn_ti	3-deoxyoctulosonyl-lipopolysaccharide hydrolase activity|alpha-Kdo-ase activity											MetaCyc:3.2.1.144-RXN|EC:3.2.1.144		molecular_function											owl:Class	
GO:0097516	biolink:NamedThing	microvillar actin bundle	A parallel bundle of actin filaments at the core of a microvillus.	got7fsn_ti							pr	2013-10-16T15:12:13Z						cellular_component											owl:Class	
GO:2000692	biolink:NamedThing	negative regulation of seed maturation	Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation.	got7fsn_ti							dhl	2011-05-13T06:41:43Z						biological_process											owl:Class	
GO:0016133	biolink:NamedThing	brassinosteroid catabolic process	The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.	got7fsn_ti	brassinosteroid breakdown|brassinosteroid catabolism|brassinosteroid degradation													biological_process											owl:Class	
GO:0071287	biolink:NamedThing	cellular response to manganese ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.	got7fsn_ti	cellular response to manganese						mah	2009-12-10T04:06:18Z						biological_process											owl:Class	
GO:0033776	biolink:NamedThing	phenylacetone monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + phenylacetone = benzyl acetate + H(2)O + NADP(+).	got7fsn_ti	PAMO|phenylacetone,NADPH:oxygen oxidoreductase activity											KEGG_REACTION:R07201|MetaCyc:1.14.13.92-RXN|RHEA:10124|EC:1.14.13.92		molecular_function											owl:Class	
GO:0030640	biolink:NamedThing	polyketide catabolic process	The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.	got7fsn_ti	polyketide breakdown|polyketide catabolism|polyketide degradation													biological_process											owl:Class	
GO:0106155	biolink:NamedThing	peptidyl-lysine 3-dioxygenase activity	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2.	got7fsn_ti							hjd	2018-11-15T20:09:45Z				RHEA:57152|EC:1.14.11.63		molecular_function											owl:Class	
GO:0031480	biolink:NamedThing	myosin X complex	A myosin complex containing one or more class X myosin heavy chains and associated light chains.	got7fsn_ti														cellular_component											owl:Class	
GO:0008805	biolink:NamedThing	carbon-monoxide oxygenase activity	Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561.	got7fsn_ti	cytochrome b561|carbon-monoxide dehydrogenase (cytochrome b-561)|carbon monoxide,water:cytochrome b-561 oxidoreductase activity|carbon monoxide oxygenase (cytochrome b-561) activity|carbon monoxide oxidase activity|carbon monoxide:methylene blue oxidoreductase activity|carbon monoxide oxygenase activity										GO:0018999|GO:0047767	EC:1.2.5.3|UM-BBD_reactionID:r0650|MetaCyc:RXN-21452|RHEA:48880|Wikipedia:Carbon-monoxide_dehydrogenase_(cytochrome_b-561)		molecular_function											owl:Class	
GO:0005250	biolink:NamedThing	A-type (transient outward) potassium channel activity	Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential.	got7fsn_ti												Reactome:R-HSA-5577234		molecular_function											owl:Class	
GO:0098690	biolink:NamedThing	glycinergic synapse	A synapse that uses glycine as a neurotransmitter.	got7fsn_ti							dos	2017-03-07T14:50:33Z						cellular_component											owl:Class	
GO:0102344	biolink:NamedThing	3-hydroxy-behenoyl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA <=> trans-2-docosenoyl-CoA + H2O.	got7fsn_ti												EC:4.2.1.134|MetaCyc:RXN-13303		molecular_function											owl:Class	
GO:0018907	biolink:NamedThing	dimethyl sulfoxide metabolic process	The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing.	got7fsn_ti	dimethyl sulfoxide metabolism|DMSO metabolism|dimethyl sulphoxide metabolism|DMSO metabolic process|dimethyl sulphoxide metabolic process											UM-BBD_pathwayID:sulf		biological_process											owl:Class	
GO:0140364	biolink:NamedThing	GW body	A ribonucleoprotein granule located in the cytoplasm and the nucleus. GW-bodies minimally contain the Argonaute2 (Ago2) and TNRC6B proteins, together with specific target RNAs.	got7fsn_ti	GW-body						pg	2019-07-25T19:26:48Z						cellular_component											owl:Class	
GO:0050917	biolink:NamedThing	sensory perception of umami taste	The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process.	got7fsn_ti	umami taste perception													biological_process											owl:Class	
GO:0004416	biolink:NamedThing	hydroxyacylglutathione hydrolase activity	Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.	got7fsn_ti	S-2-hydroxylacylglutathione hydrolase activity|acetoacetylglutathione hydrolase activity|S-(2-hydroxyacyl)glutathione hydrolase activity|glyoxalase II activity											Reactome:R-HSA-6783221|MetaCyc:GLYOXII-RXN|EC:3.1.2.6|RHEA:25245		molecular_function											owl:Class	
GO:0033200	biolink:NamedThing	inositol heptakisphosphate 5-kinase activity	Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.	got7fsn_ti	diphosphoinositol-pentakisphosphate 5-kinase activity|IP7 5-kinase activity													molecular_function											owl:Class	
GO:0043139	biolink:NamedThing	5'-3' DNA helicase activity	Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.	got7fsn_ti	DNA helicase IV activity|ATP-dependent 5'-3' DNA helicase activity|5' to 3' DNA helicase activity|ATP-dependent 5' to 3' DNA helicase activity										GO:0043141|GO:0008722	Reactome:R-HSA-6782131		molecular_function											owl:Class	
GO:0047026	biolink:NamedThing	androsterone dehydrogenase (A-specific) activity	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.	got7fsn_ti	3alpha-hydroxysteroid dehydrogenase (A-specific)|3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)|3-alpha-hydroxysteroid dehydrogenase (A-specific) activity											MetaCyc:1.1.1.213-RXN|Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(A-specific)|EC:1.1.1.213		molecular_function											owl:Class	
GO:0036269	biolink:NamedThing	swimming behavior	The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water.	got7fsn_ti	swimming behaviour						bf	2012-07-04T10:14:49Z						biological_process											owl:Class	
GO:0102103	biolink:NamedThing	demethoxycurcumin synthase	Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O <=> bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide.	got7fsn_ti												EC:2.3.1.219|MetaCyc:RXN-11223|RHEA:35119		molecular_function											owl:Class	
GO:0003851	biolink:NamedThing	2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine.	got7fsn_ti	cerebroside synthase activity|UDPgalactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity|UDPgalactose:ceramide galactosyltransferase activity|UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity|UDPgalactose:2-2-hydroxyacylsphingosine galactosyltransferase activity|UDP-galactose-ceramide galactosyltransferase activity|UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase activity|uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase activity											EC:2.4.1.47|MetaCyc:2.4.1.45-RXN|RHEA:10856		molecular_function											owl:Class	
GO:0045843	biolink:NamedThing	negative regulation of striated muscle tissue development	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.	got7fsn_ti	down-regulation of striated muscle development|inhibition of striated muscle development|down regulation of striated muscle development|downregulation of striated muscle development													biological_process											owl:Class	
GO:0033149	biolink:NamedThing	FFAT motif binding	Binding to a FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.	got7fsn_ti														molecular_function											owl:Class	
GO:0090634	biolink:NamedThing	microglial cell mediated cytotoxicity	The directed killing of a target cell by a microglial cell.	got7fsn_ti							tb	2015-04-14T14:04:54Z						biological_process											owl:Class	
GO:0019797	biolink:NamedThing	procollagen-proline 3-dioxygenase activity	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.	got7fsn_ti	procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|procollagen-proline,2-oxoglutarate 3-dioxygenase activity|prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity|proline,2-oxoglutarate 3-dioxygenase activity|prolyl 3-hydroxylase activity|protocollagen proline 3-hydroxylase activity											MetaCyc:PROCOLLAGEN-PROLINE-3-DIOXYGENASE-RXN|EC:1.14.11.7|KEGG_REACTION:R03218|RHEA:22872|Reactome:R-HSA-1980233		molecular_function											owl:Class	
GO:0018229	biolink:NamedThing	peptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine	The modification of a C-terminal peptidyl-cysteine to form peptidyl-L-cysteine methyl ester.	got7fsn_ti	peptidyl-L-cysteine methyl ester anabolism from peptidyl-cysteine|peptidyl-L-cysteine methyl ester synthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl ester formation from peptidyl-cysteine											RESID:AA0105		biological_process											owl:Class	
GO:0044526	biolink:NamedThing	formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine	The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide.	got7fsn_ti							jl	2012-03-15T09:45:19Z						biological_process											owl:Class	
GO:0071062	biolink:NamedThing	alphav-beta3 integrin-vitronectin complex	A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin.	got7fsn_ti	ITGAV-ITGB3-VTN complex						mah	2009-11-03T04:02:57Z						cellular_component											owl:Class	
GO:0031146	biolink:NamedThing	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.	got7fsn_ti	SCF-dependent proteasomal ubiquitin-dependent protein breakdown|SCF-dependent proteasomal ubiquitin-dependent protein degradation|SCF-dependent proteasomal ubiquitin-dependent protein catabolism													biological_process											owl:Class	
GO:0050548	biolink:NamedThing	trans-feruloyl-CoA hydratase activity	Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA.	got7fsn_ti	trans-feruloyl-CoA hydro-lyase activity|4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-feruloyl-CoA-forming)											RHEA:14517|EC:4.2.1.101|MetaCyc:4.2.1.101-RXN		molecular_function											owl:Class	
GO:0062153	biolink:NamedThing	C5-methylcytidine-containing RNA binding	Binding to an RNA molecule modified by C5-methylcytidine.	got7fsn_ti	C5-methylcytosine-containing RNA binding						dph	2019-09-18T14:46:22Z						molecular_function											owl:Class	
GO:0004414	biolink:NamedThing	homoserine O-acetyltransferase activity	Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA.	got7fsn_ti	homoserine transacetylase activity|homoserine acetyltransferase activity|L-homoserine O-acetyltransferase activity|homoserine O-trans-acetylase activity|acetyl-CoA:L-homoserine O-acetyltransferase activity|homoserine-O-transacetylase activity											EC:2.3.1.31|KEGG_REACTION:R01776|MetaCyc:HOMOSERINE-O-ACETYLTRANSFERASE-RXN|RHEA:13701		molecular_function											owl:Class	
GO:0018808	biolink:NamedThing	trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity	Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde.	got7fsn_ti												UM-BBD_reactionID:r0484		molecular_function											owl:Class	
GO:0042860	biolink:NamedThing	achromobactin metabolic process	The chemical reactions and pathways involving achromobactin, a citrate siderophore.	got7fsn_ti	achromobactin metabolism													biological_process											owl:Class	
GO:0004992	biolink:NamedThing	platelet activating factor receptor activity	Combining with platelet activating factor to initiate a change in cell activity.	got7fsn_ti	PAF receptor activity													molecular_function											owl:Class	
GO:0007118	biolink:NamedThing	budding cell apical bud growth	Growth at the tip of a bud, in a cell that reproduces by budding.	got7fsn_ti	apical bud growth													biological_process											owl:Class	
GO:2000826	biolink:NamedThing	regulation of heart morphogenesis	Any process that modulates the frequency, rate or extent of heart morphogenesis.	got7fsn_ti	regulation of cardiac morphogenesis						vk	2011-07-19T10:08:58Z						biological_process											owl:Class	
GO:0004452	biolink:NamedThing	isopentenyl-diphosphate delta-isomerase activity	Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.	got7fsn_ti	isopentenylpyrophosphate isomerase activity|isopentenylpyrophosphate delta-isomerase activity|IPP isomerase activity|methylbutenylpyrophosphate isomerase activity|isopentenyl-diphosphate D-isomerase activity|isopentenyl-diphosphate delta3-delta2-isomerase activity											KEGG_REACTION:R01123|RHEA:23284|MetaCyc:IPPISOM-RXN|Reactome:R-HSA-191382|EC:5.3.3.2		molecular_function											owl:Class	
GO:1902086	biolink:NamedThing	fumagillin biosynthetic process	The chemical reactions and pathways resulting in the formation of fumagillin.	got7fsn_ti	fumagillin formation|fumagillin synthesis|fumagillin anabolism|fumagillin biosynthesis						di	2013-04-25T14:00:50Z						biological_process											owl:Class	
GO:0031384	biolink:NamedThing	regulation of initiation of mating projection growth	Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0050687	biolink:NamedThing	negative regulation of defense response to virus	Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.	got7fsn_ti	negative regulation of antiviral response|downregulation of antiviral response|inhibition of antiviral response|down-regulation of antiviral response|down regulation of antiviral response													biological_process											owl:Class	
GO:0031772	biolink:NamedThing	type 2 hypocretin receptor binding	Binding to a type 2 hypocretin receptor.	got7fsn_ti	type 2 orexin receptor binding|type 2 hypocretin receptor ligand													molecular_function											owl:Class	
GO:0031290	biolink:NamedThing	retinal ganglion cell axon guidance	The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.	got7fsn_ti	retinal ganglion cell axon pathfinding													biological_process											owl:Class	
GO:0018036	biolink:NamedThing	C-terminal peptidyl-asparagine amidation	The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0083		biological_process											owl:Class	
GO:0072342	biolink:NamedThing	response to anion stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.	got7fsn_ti							mah	2010-11-05T02:25:28Z						biological_process											owl:Class	
GO:0051720	biolink:NamedThing	DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG.	got7fsn_ti														molecular_function											owl:Class	
GO:0102819	biolink:NamedThing	bixin aldehyde dehydrogenase activity	Catalysis of the reaction: bixin aldehyde + O2 + NAD <=> norbixin + NADH + H+.	got7fsn_ti												MetaCyc:RXN-8237		molecular_function											owl:Class	
GO:0036240	biolink:NamedThing	septal periplasm	The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi.	got7fsn_ti	cell wall-enclosed septal periplasm						bf	2012-05-23T10:18:09Z						cellular_component											owl:Class	
GO:0016319	biolink:NamedThing	mushroom body development	The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.	got7fsn_ti														biological_process											owl:Class	
GO:0005000	biolink:NamedThing	vasopressin receptor activity	Combining with vasopressin to initiate a change in cell activity.	got7fsn_ti	vasopressin activated calcium mobilizing receptor activity										GO:0016931			molecular_function											owl:Class	
GO:0050328	biolink:NamedThing	tetrahydroberberine oxidase activity	Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2.	got7fsn_ti	(S)-THB oxidase activity|(S)-tetrahydroberberine:oxygen oxidoreductase activity|THB oxidase activity											RHEA:13489|EC:1.3.3.8|MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN		molecular_function											owl:Class	
GO:0062211	biolink:NamedThing	root regeneration	The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root.	got7fsn_ti							dph	2020-02-21T12:47:41Z						biological_process											owl:Class	
GO:0007202	biolink:NamedThing	activation of phospholipase C activity	The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.	got7fsn_ti	phospholipase C activation				Note that this term refers to a signaling pathway, and should not be confused with function terms such as 'phospholipase activator activity ; GO:0016004'.									biological_process											owl:Class	
GO:0010863	biolink:NamedThing	positive regulation of phospholipase C activity	Any process that increases the rate of phospholipase C activity.	got7fsn_ti														biological_process											owl:Class	
GO:0007348	biolink:NamedThing	regulation of syncytial blastoderm mitotic cell cycle	A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle.	got7fsn_ti	modulation of syncytial blastoderm cell cycle progression|regulation of syncytial blastoderm cell cycle progression|syncytial blastoderm cell cycle regulation|regulation of progression through syncytial blastoderm mitotic cell cycle|syncytial blastoderm cell cycle modulation|syncytial blastoderm cell cycle regulator|regulation of syncytial blastoderm cell cycle													biological_process											owl:Class	
GO:0106297	biolink:NamedThing	E-series resolvin biosynthetic process	The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid.	got7fsn_ti							hjd	2020-08-25T13:49:46Z						biological_process											owl:Class	
GO:0019251	biolink:NamedThing	anaerobic cobalamin biosynthetic process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen.	got7fsn_ti	cobalamin biosynthetic process, anaerobic|anaerobic vitamin B12 biosynthesis|anaerobic cobalamin anabolism|anaerobic cobalamin synthesis|anaerobic cobalamin formation|vitamin B12 biosynthetic process, anaerobic|cobalamin biosynthesis, anaerobic|anaerobic cobalamin biosynthesis|vitamin B12 biosynthesis, anaerobic|anaerobic vitamin B12 biosynthetic process											MetaCyc:COBALSYN-PWY		biological_process											owl:Class	
GO:1990297	biolink:NamedThing	renal amino acid absorption	A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	got7fsn_ti							hjd	2014-02-25T22:05:57Z						biological_process											owl:Class	
GO:0042436	biolink:NamedThing	indole-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.	got7fsn_ti	indole derivative catabolic process|indole derivative catabolism|indole-containing compound breakdown|indole-containing compound catabolism|indole-containing compound degradation													biological_process											owl:Class	
GO:0047446	biolink:NamedThing	(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity	Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone.	got7fsn_ti	(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase activity|(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming)											EC:4.1.3.35|RHEA:23868|MetaCyc:4.1.3.35-RXN|KEGG_REACTION:R02232		molecular_function											owl:Class	
GO:0090710	biolink:NamedThing	phosphomevalonate decarboxylase activity	Catalysis of the reaction: ATP + (R)-mevalonate 5-phosphate = ADP + isopentenyl phosphate + CO2 + phosphate.	got7fsn_ti							tb	2016-10-21T15:59:34Z						molecular_function											owl:Class	
GO:0102080	biolink:NamedThing	phenylacetyl-coenzyme A:glycine N-acyltransferase activity	Catalysis of the reaction: phenylacetyl-CoA + glycine <=> H+ + phenylacetylglycine + coenzyme A.	got7fsn_ti												RHEA:27850|MetaCyc:RXN-10821|EC:2.3.1.192		molecular_function											owl:Class	
GO:0047232	biolink:NamedThing	galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP.	got7fsn_ti	UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase											MetaCyc:2.4.1.164-RXN|EC:2.4.1.164		molecular_function											owl:Class	
GO:0045027	biolink:NamedThing	DNA end binding	Binding to DNA ends exposed by the creation of double-strand breaks (DSBs).	got7fsn_ti														molecular_function											owl:Class	
GO:0044795	biolink:NamedThing	trans-Golgi network to recycling endosome transport	The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes.	got7fsn_ti							jl	2013-08-27T16:04:00Z						biological_process											owl:Class	
GO:0002334	biolink:NamedThing	transitional two stage B cell differentiation	The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.	got7fsn_ti	transitional two stage B-lymphocyte differentiation|transitional two stage B-cell differentiation|transitional two stage B cell development|transitional two stage B lymphocyte differentiation|T2 stage B cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1900563	biolink:NamedThing	dehydroaustinol biosynthetic process	The chemical reactions and pathways resulting in the formation of dehydroaustinol.	got7fsn_ti	dehydroaustinol formation|dehydroaustinol biosynthesis|dehydroaustinol synthesis|dehydroaustinol anabolism						di	2012-05-15T06:28:03Z						biological_process											owl:Class	
GO:0034808	biolink:NamedThing	benzo(a)pyrene 4,5-dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r1126		molecular_function											owl:Class	
GO:0044211	biolink:NamedThing	CTP salvage	Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis.	got7fsn_ti	cytidine 5'-triphosphate salvage|CTP biosynthetic process via salvage pathway						jl	2009-10-22T03:24:04Z						biological_process											owl:Class	
GO:0039639	biolink:NamedThing	suppression by virus of host cell lysis in response to superinfection	The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus.	got7fsn_ti	lysis inhibition|suppression by virus of host cell lysis in response to superinfecting virus						bf	2012-08-17T10:42:27Z						biological_process											owl:Class	
GO:0035644	biolink:NamedThing	phosphoanandamide dephosphorylation	The process of removing one or more phosphate groups from a phosphorylated anandamide.	got7fsn_ti							bf	2011-01-21T02:14:04Z						biological_process											owl:Class	
GO:0102968	biolink:NamedThing	10-hydroxygeranial oxidoreductase activity	Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP <=> (6E)-8-oxogeranial + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-9369|RHEA:32611		molecular_function											owl:Class	
GO:0050822	biolink:NamedThing	peptide stabilization	Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.	got7fsn_ti	peptide stabilisation|peptide stabilization activity													biological_process											owl:Class	
GO:0050511	biolink:NamedThing	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP.	got7fsn_ti	MurG transferase activity|UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase activity|undecaprenyldiphospho-muramoylpentapeptide b-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase activity|undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase activity				Note that EC classifies 'UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity ; GO:0051991' and 'undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity ; GO:0050511' under the same EC number, EC:2.4.1.227.							MetaCyc:RXN-8976|RHEA:23192|EC:2.4.1.227		molecular_function											owl:Class	
GO:0009015	biolink:NamedThing	N-succinylarginine dihydrolase activity	Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H(2)O + 2 H(+) = N(2)-succinyl-L-ornithine + CO(2) + 2 NH(4)(+).	got7fsn_ti	2-N-succinyl-L-arginine iminohydrolase (decarboxylating)|AstB|N2-succinyl-L-arginine iminohydrolase (decarboxylating)|arginine succinylhydrolase activity|SADH|N2-succinylarginine dihydrolase activity|succinylarginine dihydrolase activity|AruB											RHEA:19533|EC:3.5.3.23|KEGG_REACTION:R04189|MetaCyc:SUCCARGDIHYDRO-RXN		molecular_function											owl:Class	
GO:0010375	biolink:NamedThing	stomatal complex patterning	The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.	got7fsn_ti														biological_process											owl:Class	
GO:1900579	biolink:NamedThing	(17Z)-protosta-17(20),24-dien-3beta-ol metabolic process	The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol.	got7fsn_ti	(17Z)-protosta-17(20),24-dien-3beta-ol metabolism						di	2012-05-15T06:47:07Z						biological_process											owl:Class	
GO:0120002	biolink:NamedThing	fusiform vesicle	A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12996					krc	2017-02-23T21:12:27Z						cellular_component											owl:Class	
GO:0047017	biolink:NamedThing	prostaglandin-F synthase activity	Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.	got7fsn_ti	prostaglandin F synthase activity|prostaglandin-D(2) 11-ketoreductase activity|PGF2alpha synthetase activity|prostaglandin 11-ketoreductase activity|prostaglandin-D2 ketoreductase activity|prostaglandin-F synthetase activity|reductase, 15-hydroxy-11-oxoprostaglandin|synthetase, prostaglandin F2alpha|prostaglandin-D(2) 11-reductase activity|PGD(2) 11-ketoreductase activity|PGD2 11-ketoreductase activity|prostaglandin-D(2) ketoreductase activity|PGF synthetase activity|prostaglandin-D2 11-reductase activity|prostaglandin D2-ketoreductase activity|prostaglandin-D2 11-ketoreductase activity|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity|NADPH-dependent prostaglandin D2 11-keto reductase activity|prostaglandin 11-keto reductase activity|prostaglandin F synthetase activity											RHEA:10140|EC:1.1.1.188|MetaCyc:1.1.1.188-RXN		molecular_function											owl:Class	
GO:0070706	biolink:NamedThing	RNA nucleotide deletion	The modification of an RNA molecule by removal of a single nucleotide.	got7fsn_ti	RNA nucleotide excision						mah	2009-06-08T04:50:51Z						biological_process											owl:Class	
GO:0052757	biolink:NamedThing	chondroitin hydrolase activity	Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-].	got7fsn_ti	chondroitin endo-beta-galactosaminidase activity						ai	2011-09-28T10:31:53Z						molecular_function											owl:Class	
GO:0031830	biolink:NamedThing	type 5A serotonin receptor binding	Binding to a type 5A serotonin receptor.	got7fsn_ti	type 5A serotonin receptor ligand|5-hydroxytryptamine 5A receptor binding													molecular_function											owl:Class	
GO:0009834	biolink:NamedThing	plant-type secondary cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.	got7fsn_ti	cellulose and pectin-containing secondary cell wall biogenesis|secondary cell wall biosynthetic process|secondary cell wall anabolism|secondary cell wall formation|secondary cell wall synthesis|secondary cell wall biogenesis													biological_process											owl:Class	
GO:0044310	biolink:NamedThing	osmiophilic body	A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito.	got7fsn_ti							jl	2010-02-18T03:18:32Z						cellular_component											owl:Class	
GO:1901965	biolink:NamedThing	endoplasmic reticulum to chloroplast transport	The directed movement of substances from endoplasmic reticulum to chloroplast.	got7fsn_ti	ER to chloroplast transport						tb	2013-02-20T23:48:52Z						biological_process											owl:Class	
GO:0098514	biolink:NamedThing	detection of high humidity stimulus involved in sensory perception	The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity.	got7fsn_ti							dos	2013-09-25T14:20:54Z						biological_process											owl:Class	
GO:0008411	biolink:NamedThing	4-hydroxybutyrate CoA-transferase activity	Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate.	got7fsn_ti														molecular_function											owl:Class	
GO:0080032	biolink:NamedThing	methyl jasmonate esterase activity	Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol.	got7fsn_ti	MEJA esterase activity|methyl JA esterase activity|jasmonic acid methyl ester esterase activity											MetaCyc:RXN-10767		molecular_function											owl:Class	
GO:0047681	biolink:NamedThing	aryl-alcohol dehydrogenase (NADP+) activity	Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH.	got7fsn_ti	NADPH-linked benzaldehyde reductase activity|aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate)|aryl-alcohol:NADP+ oxidoreductase activity											MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN|RHEA:17761|EC:1.1.1.91		molecular_function											owl:Class	
GO:0071857	biolink:NamedThing	beta-endorphin receptor binding	Binding to a beta-endorphin receptor.	got7fsn_ti							mah	2010-09-10T03:23:01Z						molecular_function											owl:Class	
GO:0047725	biolink:NamedThing	inulosucrase activity	Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1).	got7fsn_ti	sucrose 1-fructosyltransferase activity|sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity|sucrose 1-fructosyl transferase activity											RHEA:15745|MetaCyc:INULOSUCRASE-RXN|EC:2.4.1.9		molecular_function											owl:Class	
GO:0103087	biolink:NamedThing	methylthiopentylmalate dehydrogenase activity	Catalysis of the reaction: 3-(5'-methylthio)pentylmalate <=> H+ + 2-oxo-8-methylthiooctanoate + carbon dioxide.	got7fsn_ti												MetaCyc:RXNQT-4171		molecular_function											owl:Class	
GO:0140704	biolink:NamedThing	3',2'-cyclic GMP-AMP binding	Binding to 3',2' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 2',5' linkages.	got7fsn_ti	3',2'-cGAMP binding|3',2'-cyclic GAMP binding|3',2' cyclic-GMP-AMP binding	https://github.com/geneontology/go-ontology/issues/21980					pg	2021-08-27T05:44:28Z						molecular_function											owl:Class	
GO:0014720	biolink:NamedThing	tonic skeletal muscle contraction	A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue.	got7fsn_ti														biological_process											owl:Class	
GO:0043795	biolink:NamedThing	glyceraldehyde oxidoreductase activity	Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H(+).	got7fsn_ti												EC:1.2.99.8|RHEA:36047		molecular_function											owl:Class	
GO:0046702	biolink:NamedThing	galactoside 6-L-fucosyltransferase activity	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside.	got7fsn_ti														molecular_function											owl:Class	
GO:0102009	biolink:NamedThing	proline dipeptidase activity	Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid.	got7fsn_ti												MetaCyc:3.4.13.9-RXN|EC:3.4.13.9		molecular_function											owl:Class	
GO:0002323	biolink:NamedThing	natural killer cell activation involved in immune response	The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	natural killer cell activation during immune response|NK cell activation during immune response													biological_process											owl:Class	
GO:0008475	biolink:NamedThing	procollagen-lysine 5-dioxygenase activity	Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2.	got7fsn_ti	lysine,2-oxoglutarate 5-dioxygenase activity|lysine-2-oxoglutarate dioxygenase activity|protocollagen lysine dioxygenase activity|lysyl hydroxylase activity|lysylprotocollagen dioxygenase activity|protocollagen lysine hydroxylase activity|procollagen-lysine,2-oxoglutarate 5-dioxygenase activity|protocollagen lysyl hydroxylase activity|procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)|lysine hydroxylase activity|collagen lysine hydroxylase activity											MetaCyc:PROCOLLAGEN-LYSINE-5-DIOXYGENASE-RXN|EC:1.14.11.4|RHEA:16569|Reactome:R-HSA-1981104		molecular_function											owl:Class	
GO:0047943	biolink:NamedThing	glutamate-methylamine ligase activity	Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H(+) + phosphate.	got7fsn_ti	L-glutamate:methylamine ligase (ADP-forming)|gamma-glutamylmethylamide synthetase activity											KEGG_REACTION:R01585|EC:6.3.4.12|MetaCyc:GLUTAMATE--METHYLAMINE-LIGASE-RXN|RHEA:17117		molecular_function											owl:Class	
GO:0047463	biolink:NamedThing	2-aminohexano-6-lactam racemase activity	Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam.	got7fsn_ti	alpha-amino-epsilon-caprolactam racemase activity|2-amino-hexano-6-lactam racemase activity											MetaCyc:5.1.1.15-RXN|KEGG_REACTION:R04736|EC:5.1.1.15|RHEA:14813		molecular_function											owl:Class	
GO:0033940	biolink:NamedThing	glucuronoarabinoxylan endo-1,4-beta-xylanase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans.	got7fsn_ti	endoarabinoxylanase activity|glucuronoxylan xylanohydrolase activity|glucuronoxylan xylohydrolase activity|feraxanase activity|feraxan endoxylanase activity|glucuronoarabinoxylan 1,4-beta-D-xylanohydrolase activity|glucuronoxylanase activity											MetaCyc:3.2.1.136-RXN|EC:3.2.1.136		molecular_function											owl:Class	
GO:0001968	biolink:NamedThing	fibronectin binding	Binding to a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.	got7fsn_ti														molecular_function											owl:Class	
GO:0014874	biolink:NamedThing	response to stimulus involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.	got7fsn_ti	response to stimulus involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0006427	biolink:NamedThing	histidyl-tRNA aminoacylation	The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA.	got7fsn_ti														biological_process											owl:Class	
GO:0008668	biolink:NamedThing	(2,3-dihydroxybenzoyl)adenylate synthase activity	Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate.	got7fsn_ti	ATP:2,3-dihydroxybenzoate adenylyltransferase activity|2,3-dihydroxybenzoate-AMP ligase activity											EC:2.7.7.58|MetaCyc:DHBAMPLIG-RXN|RHEA:20229|KEGG_REACTION:R01504		molecular_function											owl:Class	
GO:0047570	biolink:NamedThing	3-oxoadipate enol-lactonase activity	Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate.	got7fsn_ti	3-ketoadipate enol-lactonase activity|3-oxoadipic enol-lactone hydrolase activity|4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase activity|beta-ketoadipic enol-lactone hydrolase activity|beta-ketoadipate enol-lactone hydrolase activity|carboxymethylbutenolide lactonase activity											RHEA:10184|MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN|EC:3.1.1.24		molecular_function											owl:Class	
GO:1901605	biolink:NamedThing	alpha-amino acid metabolic process	The chemical reactions and pathways involving an alpha-amino acid.	got7fsn_ti	alpha-amino acid metabolism						tb	2012-11-08T17:39:50Z						biological_process											owl:Class	
GO:0097140	biolink:NamedThing	BIM-BCL-xl complex	A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	got7fsn_ti							pr	2011-08-02T01:41:30Z						cellular_component											owl:Class	
GO:0047688	biolink:NamedThing	aspartate 4-decarboxylase activity	Catalysis of the reaction: L-aspartate = L-alanine + CO2.	got7fsn_ti	aspartate omega-decarboxylase activity|L-aspartate 4-carboxy-lyase (L-alanine-forming)|aspartic beta-decarboxylase activity|L-aspartate beta-decarboxylase activity|L-aspartate 4-carboxy-lyase activity|L-cysteine sulfinate acid desulfinase activity|aminomalonic decarboxylase activity|aspartic omega-decarboxylase activity|cysteine sulfinic desulfinase activity|desulfinase activity|aspartate beta-decarboxylase activity											RHEA:12621|MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN|EC:4.1.1.12		molecular_function											owl:Class	
GO:0035180	biolink:NamedThing	larval wandering behavior	The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.	got7fsn_ti	larval wandering behaviour													biological_process											owl:Class	
GO:0007074	biolink:NamedThing	positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	got7fsn_ti	activation of transcription on exit from mitosis, from RNA polymerase II promoter|activation of transcription on exit from mitosis, from Pol II promoter													biological_process											owl:Class	
GO:0070737	biolink:NamedThing	protein-glycine ligase activity, elongating	Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain.	got7fsn_ti	protein glycylase activity, elongating						mah	2009-06-19T02:00:21Z						molecular_function											owl:Class	
GO:0046656	biolink:NamedThing	folic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.	got7fsn_ti	vitamin B9 biosynthesis|vitamin M biosynthesis|folic acid biosynthesis|vitamin M biosynthetic process|folate biosynthesis|folic acid formation|folate biosynthetic process|folic acid anabolism|folic acid synthesis|vitamin B9 biosynthetic process											MetaCyc:FOLSYN-PWY|Wikipedia:Folic_acid		biological_process											owl:Class	
GO:0034795	biolink:NamedThing	cyclohexane monooxygenase activity	Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O.	got7fsn_ti	butane monooxygenase activity|cyclohexane hydroxylase activity											EC:1.14.15.-|KEGG_REACTION:R06945|MetaCyc:RXN-8697|UM-BBD_reactionID:r1059		molecular_function											owl:Class	
GO:1900577	biolink:NamedThing	gerfelin catabolic process	The chemical reactions and pathways resulting in the breakdown of gerfelin.	got7fsn_ti	gerfelin degradation|gerfelin breakdown|gerfelin catabolism						di	2012-05-15T06:42:39Z						biological_process											owl:Class	
GO:0031466	biolink:NamedThing	Cul5-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.	got7fsn_ti	CDL5 complex|cullin-RING ligase 5|CRL5 complex|SCF5 complex|EC2S complex													cellular_component											owl:Class	
GO:0030124	biolink:NamedThing	AP-4 adaptor complex	An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.	got7fsn_ti														cellular_component											owl:Class	
GO:0047386	biolink:NamedThing	fructose-2,6-bisphosphate 6-phosphatase activity	Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose 2-phosphate + phosphate.	got7fsn_ti	D-fructose-2,6-bisphosphate 6-phosphohydrolase activity|fructose 2,6-bisphosphate-6-phosphohydrolase activity|fructose-2,6-bisphosphate 6-phosphohydrolase activity|beta-D-fructose-2,6-bisphosphate 6-phosphohydrolase activity											KEGG_REACTION:R02730|EC:3.1.3.54|MetaCyc:3.1.3.54-RXN|RHEA:13333		molecular_function											owl:Class	
GO:0098569	biolink:NamedThing	internal side of mycolate outer membrane	The side of the mycolate outer membrane that faces the cell wall peptidoglycan. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network.	got7fsn_ti														cellular_component											owl:Class	
GO:1900584	biolink:NamedThing	o-orsellinic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of o-orsellinic acid.	got7fsn_ti	o-orsellinic acid synthesis|o-orsellinic acid biosynthesis|o-orsellinic acid anabolism|o-orsellinic acid formation						di	2012-05-15T06:48:11Z						biological_process											owl:Class	
GO:0032902	biolink:NamedThing	nerve growth factor production	The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	NGF production|beta-nerve growth factor production													biological_process											owl:Class	
GO:0060098	biolink:NamedThing	membrane reorganization involved in phagocytosis, engulfment	The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	got7fsn_ti	membrane reorganisation involved in phagocytosis, engulfment													biological_process											owl:Class	
GO:0003920	biolink:NamedThing	GMP reductase activity	Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.	got7fsn_ti	NADPH:guanosine-5'-phosphate oxidoreductase (deaminating) activity|guanylate reductase activity|guanosine 5'-monophosphate reductase activity|guanosine 5'-monophosphate oxidoreductase activity|guanosine 5'-phosphate reductase activity|NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating)|NADPH:GMP oxidoreductase (deaminating) activity|guanosine monophosphate reductase activity|inosine-5'-phosphate:NADP+ oxidoreductase (aminating)				Note that this function was formerly EC:1.6.6.8.							Reactome:R-HSA-514604|MetaCyc:GMP-REDUCT-RXN|RHEA:17185|KEGG_REACTION:R01134|EC:1.7.1.7		molecular_function											owl:Class	
GO:0051217	biolink:NamedThing	molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)	The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).	got7fsn_ti												RESID:AA0375		biological_process											owl:Class	
GO:0150008	biolink:NamedThing	bulk synaptic vesicle endocytosis	Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse.	got7fsn_ti	activity-dependent bulk synaptic vesicle endocytosis|ADBE|bulk endocytosis|activity-dependent bulk endocytosis						bc	2017-12-01T10:20:18Z						biological_process											owl:Class	
GO:0008704	biolink:NamedThing	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity	Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate.	got7fsn_ti	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase|5-carboxymethyl-2-hydroxymuconic acid isomerase activity|HHDD isomerase activity|hpaG1|5-carboxymethyl-2-hydroxymuconate delta2,Delta4-2-oxo,Delta3-isomerase activity|hpaG-1|CHM isomerase activity|5-carboxymethyl-2-hydroxymuconate D-isomerase activity										GO:0018843	MetaCyc:5.3.3.10-RXN|UM-BBD_reactionID:r0366|EC:5.3.3.10|RHEA:18813		molecular_function											owl:Class	
GO:0035189	biolink:NamedThing	Rb-E2F complex	A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression.	got7fsn_ti	retinoblastoma-E2F complex													cellular_component											owl:Class	
GO:0005499	biolink:NamedThing	vitamin D binding	Binding to vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	got7fsn_ti	ergocalciferol binding|calciferol binding|cholecalciferol binding													molecular_function											owl:Class	
GO:0004306	biolink:NamedThing	ethanolamine-phosphate cytidylyltransferase activity	Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.	got7fsn_ti	CTP:phosphoethanolamine cytidylyltransferase activity|ET|phosphorylethanolamine transferase activity|phosphoethanolamine cytidylyltransferase activity|CTP:ethanolamine-phosphate cytidylyltransferase activity|CTP-phosphoethanolamine cytidylyltransferase activity|ethanolamine phosphate cytidylyltransferase activity											Reactome:R-HSA-1483190|EC:2.7.7.14|RHEA:24592|MetaCyc:2.7.7.14-RXN		molecular_function											owl:Class	
GO:0034879	biolink:NamedThing	2,3,6-trihydroxyisonicotinate decarboxylase activity	Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2.	got7fsn_ti												UM-BBD_reactionID:r1340		molecular_function											owl:Class	
GO:0016216	biolink:NamedThing	isopenicillin-N synthase activity	Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N.	got7fsn_ti	N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine:oxygen oxidoreductase (cyclizing)|isopenicillin-N synthetase activity|isopenicillin N synthase activity											MetaCyc:1.21.3.1-RXN|EC:1.21.3.1|RHEA:22428|KEGG_REACTION:R04872		molecular_function											owl:Class	
GO:0031724	biolink:NamedThing	CXCR5 chemokine receptor binding	Binding to a CXCR5 chemokine receptor.	got7fsn_ti	CXCR5 chemokine receptor ligand|type 1 Burkitt's lymphoma receptor binding													molecular_function											owl:Class	
GO:0034824	biolink:NamedThing	citronellyl-CoA dehydrogenase activity	Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r1159		molecular_function											owl:Class	
GO:0030223	biolink:NamedThing	neutrophil differentiation	The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.	got7fsn_ti	neutrophil granulocyte differentiation|neutrophil granulocytopoiesis|neutrophil cell differentiation													biological_process											owl:Class	
GO:0047639	biolink:NamedThing	alcohol oxidase activity	Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2.	got7fsn_ti	AOX activity|ethanol oxidase activity|alcohol:oxygen oxidoreductase activity				Note that the enzyme alcohol oxidase also has methanol oxidase activity (GO:0046563).							EC:1.1.3.13|MetaCyc:ALCOHOL-OXIDASE-RXN|RHEA:19829		molecular_function											owl:Class	
GO:0044396	biolink:NamedThing	actin cortical patch organization	A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis.	got7fsn_ti	actin cortical patch organisation						jl	2011-12-21T03:33:25Z						biological_process											owl:Class	
GO:0052835	biolink:NamedThing	inositol-3,4,6-trisphosphate 1-kinase activity	Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+).	got7fsn_ti	1D-myo-inositol-trisphosphate 1-kinase activity|IP3 1-kinase activity|ins(3,4,6)P(3) 1-kinase activity|Ins(3,4,6)P3 1-kinase activity|inositol-trisphosphate 1-kinase activity|inositol 3,4,6-trisphosphate 1-kinase activity|ATP:1D-myo-inositol-3,4,6-trisphosphate 1-phosphotransferase activity						ai	2011-11-29T01:06:01Z				EC:2.7.1.-|Reactome:R-HSA-1855169		molecular_function											owl:Class	
GO:0044365	biolink:NamedThing	envenomation resulting in modulation of platelet aggregation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism.	got7fsn_ti	envenomation resulting in regulation of platelet aggregation in other organism						jl	2011-10-27T02:36:43Z						biological_process											owl:Class	
GO:0140454	biolink:NamedThing	protein aggregate center assembly	The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.	got7fsn_ti	PAC assembly|protein aggregate center formation|protein aggregate centre assembly	https://github.com/geneontology/go-ontology/issues/19172					pg	2020-04-20T15:43:52Z						biological_process											owl:Class	
GO:0051795	biolink:NamedThing	positive regulation of timing of catagen	Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.	got7fsn_ti	up-regulation of catagen|upregulation of catagen|stimulation of catagen|positive regulation of catagen|up regulation of catagen|activation of catagen													biological_process											owl:Class	
GO:0047052	biolink:NamedThing	(S)-stylopine synthase activity	Catalysis of the reaction: (S)-cheilanthifoline + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-stylopine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	got7fsn_ti	(S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming) activity|(S)-cheilanthifoline,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)	https://github.com/geneontology/go-ontology/issues/21133										KEGG_REACTION:R04690|EC:1.14.19.64|RHEA:13773|MetaCyc:1.1.3.32-RXN		molecular_function											owl:Class	
GO:0102417	biolink:NamedThing	apigenin-7-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose <=> apigenin-7-O-gentiobioside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13800		molecular_function											owl:Class	
GO:0016401	biolink:NamedThing	palmitoyl-CoA oxidase activity	Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide.	got7fsn_ti												EC:1.3.3.-		molecular_function											owl:Class	
GO:0018570	biolink:NamedThing	p-cumate 2,3-dioxygenase activity	Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.	got7fsn_ti												RHEA:42344|UM-BBD_reactionID:r0395|EC:1.14.12.25|MetaCyc:RXN-664		molecular_function											owl:Class	
GO:0047597	biolink:NamedThing	6-oxocineole dehydrogenase activity	Catalysis of the reaction: 6-oxocineole + H(+) + NADPH + O(2) = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H(2)O + NADP(+).	got7fsn_ti	6-oxocineole oxygenase activity|6-oxocineole,NADPH:oxygen oxidoreductase activity											EC:1.14.13.51|KEGG_REACTION:R02995|MetaCyc:6-OXOCINEOLE-DEHYDROGENASE-RXN|RHEA:24324		molecular_function											owl:Class	
GO:0042392	biolink:NamedThing	sphingosine-1-phosphate phosphatase activity	Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.	got7fsn_ti	sphingosine-1-phosphate phosphohydrolase activity|SPPase activity|SPP phosphatase activity											RHEA:27518|MetaCyc:RXN3DJ-25|Reactome:R-HSA-428696|Reactome:R-HSA-428701|Reactome:R-HSA-428690		molecular_function											owl:Class	
GO:0034029	biolink:NamedThing	2-oxoglutarate carboxylase activity	Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate.	got7fsn_ti	CFI|oxalosuccinate synthetase activity|OGC|carboxylating factor for ICDH											MetaCyc:RXN-8457|RHEA:20425|KEGG_REACTION:R08201|EC:6.4.1.7		molecular_function											owl:Class	
GO:1900792	biolink:NamedThing	shamixanthone catabolic process	The chemical reactions and pathways resulting in the breakdown of shamixanthone.	got7fsn_ti	shamixanthone breakdown|shamixanthone catabolism|shamixanthone degradation						di	2012-06-04T09:40:42Z						biological_process											owl:Class	
GO:0047580	biolink:NamedThing	4-hydroxyproline epimerase activity	Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.	got7fsn_ti	L-hydroxyproline epimerase activity|hydroxyproline epimerase activity|4-hydroxyproline 2-epimerase activity|hydroxyproline 2-epimerase activity											KEGG_REACTION:R03296|MetaCyc:4-HYDROXYPROLINE-EPIMERASE-RXN|RHEA:21152|EC:5.1.1.8		molecular_function											owl:Class	
GO:0051798	biolink:NamedThing	positive regulation of hair follicle development	Any process that activates or increases the frequency, rate or extent of hair follicle development.	got7fsn_ti	up-regulation of hair follicle development|up regulation of hair follicle development|activation of hair follicle development|stimulation of hair follicle development|upregulation of hair follicle development													biological_process											owl:Class	
GO:0051743	biolink:NamedThing	red chlorophyll catabolite reductase activity	Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence.	got7fsn_ti	RCC reductase activity											MetaCyc:RXN-7741|RHEA:24752		molecular_function											owl:Class	
GO:0042268	biolink:NamedThing	regulation of cytolysis	Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm.	got7fsn_ti														biological_process											owl:Class	
GO:0050441	biolink:NamedThing	3-ethylmalate synthase activity	Catalysis of the reaction: butanoyl-CoA + glyoxylate + H(2)O = 3-ethylmalate + CoA + H(+).	got7fsn_ti	butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming)|3-ethylmalate glyoxylate-lyase (CoA-butanoylating) activity|2-ethyl-3-hydroxybutanedioate synthase activity											EC:2.3.3.7|KEGG_REACTION:R01180|MetaCyc:3-ETHYLMALATE-SYNTHASE-RXN|RHEA:10500		molecular_function											owl:Class	
GO:0008878	biolink:NamedThing	glucose-1-phosphate adenylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate.	got7fsn_ti	ADPG pyrophosphorylase activity|ADP-glucose pyrophosphorylase activity|adenosine diphosphate glucose pyrophosphorylase activity|ATP:alpha-glucose-1-phosphate adenylyl transferase activity|ADGase activity|ADP:alpha-D-glucose-1-phosphate adenylyltransferase activity|ADP glucose pyrophosphorylase activity|ADP-glucose synthetase activity|adenosine diphosphoglucose pyrophosphorylase activity|ADP-glucose synthase activity|ADP-glucose diphosphorylase activity|ATP:alpha-D-glucose-1-phosphate adenylyltransferase activity|glucose 1-phosphate adenylyltransferase activity											KEGG_REACTION:R00948|RHEA:12120|EC:2.7.7.27|MetaCyc:GLUC1PADENYLTRANS-RXN		molecular_function											owl:Class	
GO:0007541	biolink:NamedThing	sex determination, primary response to X:A ratio	The developmental process in which an organism interprets its X to autosomal chromosomal complement.	got7fsn_ti														biological_process											owl:Class	
GO:0031009	biolink:NamedThing	plastid ADPG pyrophosphorylase complex	An ADPG pyrophosphorylase complex found in a plastid.	got7fsn_ti														cellular_component											owl:Class	
GO:0046511	biolink:NamedThing	sphinganine biosynthetic process	The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol.	got7fsn_ti	sphinganine anabolism|dihydrosphingosine biosynthetic process|sphinganine synthesis|dihydrosphingosine biosynthesis|sphinganine formation|sphinganine biosynthesis													biological_process											owl:Class	
GO:0033862	biolink:NamedThing	UMP kinase activity	Catalysis of the reaction: ATP + UMP = ADP + UDP.	got7fsn_ti	uridine monophosphate kinase activity|SmbA|ATP:UMP phosphotransferase activity|PyrH|UMPK|UMP-kinase activity											MetaCyc:2.7.4.22-RXN|EC:2.7.4.22|RHEA:24400		molecular_function											owl:Class	
GO:0051401	biolink:NamedThing	CH domain binding	Binding to a calponin homology protein domain, a domain of 100 residues that occurs in signaling and cytoskeletal proteins.	got7fsn_ti	calponin homology domain binding													molecular_function											owl:Class	
GO:2001043	biolink:NamedThing	positive regulation of septum digestion after cytokinesis	Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.	got7fsn_ti	positive regulation of cytokinetic cell separation|positive regulation of cell separation after cytokinesis						mcc	2011-08-30T05:16:57Z						biological_process											owl:Class	
GO:0021790	biolink:NamedThing	chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	got7fsn_ti	negative chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme													biological_process											owl:Class	
GO:0060352	biolink:NamedThing	cell adhesion molecule production	The appearance of a cell adhesion molecule due to biosynthesis or secretion.	got7fsn_ti														biological_process											owl:Class	
GO:0050257	biolink:NamedThing	riboflavin phosphotransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN.	got7fsn_ti	D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity|alpha-D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity|riboflavine phosphotransferase activity|G-1-P phosphotransferase activity											RHEA:20409|MetaCyc:RIBOFLAVIN-PHOSPHOTRANSFERASE-RXN|KEGG_REACTION:R00550|EC:2.7.1.42		molecular_function											owl:Class	
GO:0043252	biolink:NamedThing	sodium-independent organic anion transport	The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0097499	biolink:NamedThing	protein localization to non-motile cilium	A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.	got7fsn_ti	protein localization to nonmotile primary cilium						pr	2013-08-13T12:16:26Z						biological_process											owl:Class	
GO:0008894	biolink:NamedThing	guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity	Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate.	got7fsn_ti	pppGpp 5'-phosphohydrolase activity|guanosine pentaphosphatase activity|guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase activity|guanosine pentaphosphate phosphatase activity|guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase activity|guanosine pentaphosphate phosphohydrolase activity|guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase activity|guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase activity											MetaCyc:PPPGPPHYDRO-RXN|RHEA:13073|EC:3.6.1.40		molecular_function											owl:Class	
GO:0032795	biolink:NamedThing	heterotrimeric G-protein binding	Binding to a heterotrimeric G-protein.	got7fsn_ti														molecular_function											owl:Class	
GO:1990308	biolink:NamedThing	type-I dockerin domain binding	Binding to a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain.	got7fsn_ti							tt	2014-03-07T03:10:37Z						molecular_function											owl:Class	
GO:0019927	biolink:NamedThing	peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone	The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase.	got7fsn_ti												RESID:AA0313		biological_process											owl:Class	
GO:2000954	biolink:NamedThing	regulation of cyclodextrin metabolic process	Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process.	got7fsn_ti	regulation of cyclodextrin metabolism						tt	2011-08-01T02:22:00Z						biological_process											owl:Class	
GO:1990534	biolink:NamedThing	thermospermine oxidase activity	Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine.	got7fsn_ti							tb	2014-11-13T00:41:59Z						molecular_function											owl:Class	
GO:0033188	biolink:NamedThing	sphingomyelin synthase activity	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin.	got7fsn_ti	SM synthase activity|SMS1|ceramide:phosphatidylcholine cholinephosphotransferase activity|SMS2|phosphatidylcholine:ceramide cholinephosphotransferase activity											MetaCyc:2.7.8.27-RXN|EC:2.7.8.27|Reactome:R-HSA-429786|Reactome:R-HSA-429798|KEGG_REACTION:R08969|RHEA:18765		molecular_function											owl:Class	
GO:0048487	biolink:NamedThing	beta-tubulin binding	Binding to the microtubule constituent protein beta-tubulin.	got7fsn_ti	beta tubulin binding													molecular_function											owl:Class	
GO:0047779	biolink:NamedThing	citrate-CoA ligase activity	Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H(+) + phosphate.	got7fsn_ti	citrate thiokinase activity|citrate:CoA ligase (ADP-forming)|citrate:CoA ligase activity|citryl-CoA synthetase activity											KEGG_REACTION:R01322|RHEA:21472|MetaCyc:CITRATE--COA-LIGASE-RXN|EC:6.2.1.18		molecular_function											owl:Class	
GO:0032979	biolink:NamedThing	protein insertion into mitochondrial inner membrane from matrix	The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.	got7fsn_ti	protein insertion into mitochondrial membrane from inner side|insertion of proteins into the mitochondrial membrane from the inner side|protein insertion into mitochondrial inner membrane from matrix side													biological_process											owl:Class	
GO:0034929	biolink:NamedThing	1-hydroxypyrene 7,8-monooxygenase activity	Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O.	got7fsn_ti												UM-BBD_reactionID:r0949		molecular_function											owl:Class	
GO:0047051	biolink:NamedThing	D-lactate dehydrogenase (cytochrome c-553) activity	Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c553] = 2 [Fe(II)cytochrome c553] + 2 H+ + pyruvate.	got7fsn_ti	(R)-lactate:ferricytochrome-c-553 2-oxidoreductase activity											MetaCyc:1.1.2.5-RXN|RHEA:16465|EC:1.1.2.5		molecular_function											owl:Class	
GO:0043864	biolink:NamedThing	indoleacetamide hydrolase activity	Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA.	got7fsn_ti	indole-3-acetamide hydrolase activity|IAH|IaaH|indole acetamide hydrolase activity|Tms2											MetaCyc:G-5841|EC:3.5.1.4|RHEA:34371		molecular_function											owl:Class	
GO:0018541	biolink:NamedThing	p-benzoquinone reductase (NADPH) activity	Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+).	got7fsn_ti	NADPH:p-benzoquinone oxidoreductase activity											KEGG_REACTION:R05244|UM-BBD_enzymeID:e0422|EC:1.6.5.6|RHEA:23488|MetaCyc:1.6.5.6-RXN		molecular_function											owl:Class	
GO:0090217	biolink:NamedThing	negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	got7fsn_ti							tb	2010-01-12T10:00:45Z						biological_process											owl:Class	
GO:0098595	biolink:NamedThing	perivitelline space	The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).	got7fsn_ti							dos	2014-04-08T16:07:31Z						cellular_component											owl:Class	
GO:0102547	biolink:NamedThing	glucosylglycerate hydrolase activity	Catalysis of the reaction: H2O + 2-O-(alpha-D-glucopyranosyl)-D-glycerate <=> alpha-D-glucose + D-glycerate.	got7fsn_ti												MetaCyc:RXN-14901|RHEA:32059		molecular_function											owl:Class	
GO:0047612	biolink:NamedThing	acid-CoA ligase (GDP-forming) activity	Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H(+) + phosphate.	got7fsn_ti	acid:CoA ligase (GDP-forming)|acyl-CoA synthetase (GDP-forming) activity|acyl coenzyme A synthetase (guanosine diphosphate forming)											EC:6.2.1.10|MetaCyc:ACID--COA-LIGASE-GDP-FORMING-RXN|RHEA:10968|KEGG_REACTION:R00394		molecular_function											owl:Class	
GO:0090508	biolink:NamedThing	phenylethylamine biosynthetic process involved in synaptic transmission	The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission.	got7fsn_ti							tb	2012-11-15T15:10:23Z						biological_process											owl:Class	
GO:0003693	biolink:NamedThing	P-element binding	Binding to a P-element, a class of Drosophila transposon responsible for hybrid dysgenesis.	got7fsn_ti														molecular_function											owl:Class	
GO:0016752	biolink:NamedThing	sinapoyltransferase activity	Catalysis of the transfer of a sinapoyl group to an acceptor molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:0061044	biolink:NamedThing	negative regulation of vascular wound healing	Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.	got7fsn_ti							dph	2010-02-25T10:24:28Z						biological_process											owl:Class	
GO:0050219	biolink:NamedThing	prostaglandin-A1 delta-isomerase activity	Catalysis of the reaction: prostaglandin A1 = prostaglandin C1.	got7fsn_ti	prostaglandin-A1 D-isomerase activity|(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate delta10-delta11-isomerase activity|prostaglandin A isomerase activity											MetaCyc:PROSTAGLANDIN-A1-DELTA-ISOMERASE-RXN|RHEA:10460|EC:5.3.3.9|KEGG_REACTION:R04565		molecular_function											owl:Class	
GO:1990473	biolink:NamedThing	ciliary targeting signal binding	Binding to a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane.	got7fsn_ti	CTS binding						pr	2014-09-02T08:22:03Z						molecular_function											owl:Class	
GO:0043644	biolink:NamedThing	tetracycline biosynthetic process	The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).	got7fsn_ti	tetracyclin biosynthesis|tetracyclin biosynthetic process													biological_process											owl:Class	
GO:0047020	biolink:NamedThing	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.	got7fsn_ti	dehydrogenase, prostaglandin D2|prostaglandin-D 15-dehydrogenase (NADP(+)) activity|15-hydroxyprostaglandin dehydrogenase (NADP)|15-hydroxy PGD2 dehydrogenase activity|(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity|prostaglandin D2 dehydrogenase activity|NADP-PGD2 dehydrogenase activity|prostaglandin-D 15-dehydrogenase (NADP+) activity|prostaglandin-D 15-dehydrogenase (NADP)|dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate)|NADP-linked prostaglandin D2 dehydrogenase activity|NADP-dependent 15-hydroxyprostaglandin dehydrogenase|NADP-linked 15-hydroxyprostaglandin dehydrogenase|NADP-specific 15-hydroxyprostaglandin dehydrogenase											RHEA:20744|EC:1.1.1.196|MetaCyc:1.1.1.196-RXN		molecular_function											owl:Class	
GO:0000970	biolink:NamedThing	tRNA exon ligation utilizing GTP as source of linkage phosphate	A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process.	got7fsn_ti							krc	2009-04-28T10:33:25Z						biological_process											owl:Class	
GO:0072521	biolink:NamedThing	purine-containing compound metabolic process	The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.	got7fsn_ti	purine and derivative metabolic process|purine-containing compound metabolism						mah	2011-01-04T03:03:59Z						biological_process											owl:Class	
GO:0009073	biolink:NamedThing	aromatic amino acid family biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).	got7fsn_ti	aromatic amino acid family formation|aromatic amino acid family biosynthetic process, shikimate pathway|aromatic amino acid family biosynthesis|aromatic amino acid family anabolism|aromatic amino acid family synthesis										GO:0016089	MetaCyc:COMPLETE-ARO-PWY		biological_process											owl:Class	
GO:1990920	biolink:NamedThing	proteasome localization to nuclear periphery	Any process in which the proteasome is transported to, or maintained at the nuclear periphery.	got7fsn_ti							vw	2015-12-14T17:14:00Z						biological_process											owl:Class	
GO:0031144	biolink:NamedThing	proteasome localization	Any process in which the proteasome is transported to, or maintained in, a specific location.	got7fsn_ti	establishment and maintenance of proteasome localization|proteasome localisation													biological_process											owl:Class	
GO:0010044	biolink:NamedThing	response to aluminum ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.	got7fsn_ti	response to aluminium ion|response to aluminum													biological_process											owl:Class	
GO:0042333	biolink:NamedThing	chemotaxis to oxidizable substrate	The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose.	got7fsn_ti	taxis in response to oxidizable substrate													biological_process											owl:Class	
GO:1990603	biolink:NamedThing	dark adaptation	The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light.	got7fsn_ti					The proteins RGS9-1 and Gb5L localize to the rod inner segment during dark adaptation, but to the rod outer segment during light adaptation. PMID:23555598		hjd	2015-01-09T20:35:46Z						biological_process											owl:Class	
GO:0072754	biolink:NamedThing	cellular response to purvalanol A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.	got7fsn_ti							mah	2012-11-07T12:05:57Z						biological_process											owl:Class	
GO:0047357	biolink:NamedThing	UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H(+) + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP.	got7fsn_ti	uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase activity|galactose-1-phosphotransferase activity|UDPgalactose-UDP-N-acetylglucosamine galactose phosphotransferase activity|galactosyl phosphotransferase activity|UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity|UDPgalactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity											MetaCyc:2.7.8.18-RXN|RHEA:22440|EC:2.7.8.18|KEGG_REACTION:R00504		molecular_function											owl:Class	
GO:0019085	biolink:NamedThing	early viral transcription	The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell.	got7fsn_ti	immediate early viral mRNA transcription													biological_process											owl:Class	
GO:0102699	biolink:NamedThing	2-methylpropionitrile hydroxylase activity	Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH <=> 2-hydroxy-2-methylpropanenitrile + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-5082|RHEA:51964		molecular_function											owl:Class	
GO:0102527	biolink:NamedThing	8-demethylnovobiocate synthase activity	Catalysis of the reaction: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP(4-) <=> H+ + 8-desmethylnovobiocic acid(1-) + AMP(2-) + diphosphoric acid.	got7fsn_ti												RHEA:36699|MetaCyc:RXN-14547|EC:6.3.1.15		molecular_function											owl:Class	
GO:0021811	biolink:NamedThing	growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration	Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex.	got7fsn_ti	growth factor signalling initiating cell movement involved in cerebral cortex glial-mediated radial migration|growth factor signaling initiating cell movement involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0034480	biolink:NamedThing	phosphatidylcholine phospholipase C activity	Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate.	got7fsn_ti	lipophosphodiesterase I activity|heat-labile hemolysin|phospholipase C, acting on phosphatidylcholine|Clostridium welchii alpha-toxin activity|Clostridium oedematiens beta- and gamma-toxins activity|alpha-toxin|phosphatidylcholine cholinephosphohydrolase activity											EC:3.1.4.3|MetaCyc:PHOSPHOLIPASE-C-RXN|RHEA:10604		molecular_function											owl:Class	
GO:0047559	biolink:NamedThing	3-dehydro-L-gulonate 2-dehydrogenase activity	Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.	got7fsn_ti	3-keto-L-gulonate dehydrogenase activity|3-ketogulonate dehydrogenase activity|3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity|2,3-diketo-L-gulonate reductase activity											EC:1.1.1.130|MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:0070284	biolink:NamedThing	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity	Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine.	got7fsn_ti	HMP-P synthase activity|ThiC													molecular_function											owl:Class	
GO:0036030	biolink:NamedThing	protein C inhibitor-plasma kallikrein complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein.	got7fsn_ti	PCI-plasma kallikrein complex|protein C inhibitor-KLKB1 complex|serpin A5-plasma kallikrein complex|plasma serine protease inhibitor-plasma kallikrein complex|SERPINA5-plasma kallikrein complex						bf	2011-10-19T02:05:46Z						cellular_component											owl:Class	
GO:0061593	biolink:NamedThing	sulfoquinovose isomerase activity	Catalysis of the reaction sulfoquinovose = 6-deoxy-6-sulfofructose.	got7fsn_ti							dph	2014-02-10T09:56:04Z						molecular_function											owl:Class	
GO:0003832	biolink:NamedThing	beta-alanyl-dopamine hydrolase activity	Catalysis of the reaction: N-beta-alanyl dopamine + H2O = dopamine + beta-alanine.	got7fsn_ti	NBAD hydrolase activity|N-beta-alanyl-dopamine hydrolase activity													molecular_function											owl:Class	
GO:0001821	biolink:NamedThing	histamine secretion	The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems.	got7fsn_ti														biological_process											owl:Class	
GO:0003133	biolink:NamedThing	endodermal-mesodermal cell signaling	Any process that mediates the transfer of information from endodermal cells to mesodermal cells.	got7fsn_ti	endodermal-mesodermal cell signalling						tb	2009-09-22T03:10:29Z						biological_process											owl:Class	
GO:0010394	biolink:NamedThing	homogalacturonan metabolic process	The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.	got7fsn_ti	homogalacturonan metabolism													biological_process											owl:Class	
GO:0034211	biolink:NamedThing	GTP-dependent protein kinase activity	GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.	got7fsn_ti					The reaction requires the presence of GTP.									molecular_function											owl:Class	
GO:0050272	biolink:NamedThing	S-carboxymethylcysteine synthase activity	Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H(+).	got7fsn_ti	3-chloro-L-alanine chloride-lyase (adding thioglycolate)|S-carboxymethyl-L-cysteine synthase activity|3-chloro-L-alanine chloride-lyase (adding thioglycolate; S-carboxymethyl-L-cysteine-forming)											EC:4.5.1.5|KEGG_REACTION:R04003|RHEA:22868|MetaCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0047862	biolink:NamedThing	diisopropyl-fluorophosphatase activity	Catalysis of the reaction: diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + 2 H(+) + hydrogen fluoride.	got7fsn_ti	diisopropyl-fluorophosphate fluorohydrolase activity|isopropylphosphorofluoridase activity|OPAA activity|tabunase activity|diisopropylfluorophosphonate dehalogenase activity|organophosphate acid anhydrase activity|diisopropyl phosphorofluoridate hydrolase activity|dialkylfluorophosphatase activity|diisopropylphosphofluoridase activity|DFPase activity|organophosphorus acid anhydrolase activity|OPA anhydrase activity|somanase activity											RHEA:24100|KEGG_REACTION:R01533|MetaCyc:DIISOPROPYL-FLUOROPHOSPHATASE-RXN|EC:3.1.8.2		molecular_function											owl:Class	
GO:0052767	biolink:NamedThing	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity	Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.	got7fsn_ti	alpha-1,6-mannosidase activity|1,6-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,6-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|1,6-alpha-mannosidase activity						ai	2011-09-30T12:55:24Z				EC:3.1.1.-		molecular_function											owl:Class	
GO:0051698	biolink:NamedThing	saccharopine oxidase activity	Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2.	got7fsn_ti	SAX activity													molecular_function											owl:Class	
GO:0102632	biolink:NamedThing	(S)-nandinine synthase activity	Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-nandinine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21133										RHEA:50364|MetaCyc:RXN-15538|EC:1.14.19.73		molecular_function											owl:Class	
GO:1904019	biolink:NamedThing	epithelial cell apoptotic process	Any apoptotic process in an epithelial cell.	got7fsn_ti	epitheliocyte apoptotic process|epitheliocyte apoptosis|epithelial cell apoptosis						sl	2015-03-06T22:27:17Z						biological_process											owl:Class	
GO:1990606	biolink:NamedThing	membrane scission GTPase motor activity	Generation of a 'twisting' activity resulting in the scission of a membrane, driven by GTP hydrolysis.	got7fsn_ti							vw	2015-01-19T14:26:50Z						molecular_function											owl:Class	
GO:0102006	biolink:NamedThing	4-methyl-2-oxopentanoate dehydrogenase activity	Catalysis of the reaction: 4-methyl-2-oxopentanoate + coenzyme A(4-) + NAD(1-) <=> isovaleryl-CoA(4-) + carbon dioxide + NADH(2-).	got7fsn_ti												MetaCyc:2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN|RHEA:25177		molecular_function											owl:Class	
GO:0102031	biolink:NamedThing	4-acetamido-4,6-dideoxy-D-galactose transferase activity	Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP.	got7fsn_ti												EC:2.4.1.325|RHEA:28759|MetaCyc:FUC4NACTRANS-RXN		molecular_function											owl:Class	
GO:0002567	biolink:NamedThing	somatic diversification of FREP-based immune receptors	The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails.	got7fsn_ti					Note that this type of immune receptor has been found in snails (Pulmonata, ncbi_axonomy_id:6519), but may also be seen in other species.									biological_process											owl:Class	
GO:0085016	biolink:NamedThing	dormancy exit of symbiont in host	Exit from dormant state, also known as resuscitation, of the symbiont within the host organism.	got7fsn_ti	resuscitation of symbiont						jl	2010-05-19T03:23:07Z						biological_process											owl:Class	
GO:0044519	biolink:NamedThing	envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.	got7fsn_ti	envenomation resulting in modulation of VIP receptor activity in other organism|envenomation resulting in regulation of vasoactive intestinal polypeptide receptor activity in other organism|envenomation resulting in regulation of VIP receptor activity in other organism						jl	2012-02-26T11:53:33Z						biological_process											owl:Class	
GO:0034575	biolink:NamedThing	4-isopropylaniline dehydrogenase activity	Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0901|EC:1.17.99.-		molecular_function											owl:Class	
GO:0051919	biolink:NamedThing	positive regulation of fibrinolysis	Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.	got7fsn_ti	upregulation of fibrinolysis|stimulation of fibrinolysis|up regulation of fibrinolysis|activation of fibrinolysis|up-regulation of fibrinolysis													biological_process											owl:Class	
GO:0000424	biolink:NamedThing	micromitophagy	Degradation of a mitochondrion by lysosomal microautophagy.	got7fsn_ti					Note that this term is not a child of mitophagy because the community genrally uses that latter to refer to the macroautophagy of mitochondria.									biological_process											owl:Class	
GO:0035507	biolink:NamedThing	regulation of myosin-light-chain-phosphatase activity	Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.	got7fsn_ti							bf	2010-04-30T10:53:38Z						biological_process											owl:Class	
GO:0050614	biolink:NamedThing	delta24-sterol reductase activity	Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.	got7fsn_ti	lanosterol delta24-reductase activity|lanosterol Delta(24)-reductase activity|D24-sterol reductase activity|sterol:NADP+ delta24-oxidoreductase activity											MetaCyc:1.3.1.72-RXN|EC:1.3.1.72|Reactome:R-HSA-6807064|RHEA:13685|Reactome:R-HSA-196417		molecular_function											owl:Class	
GO:0072100	biolink:NamedThing	specification of ureteric bud anterior/posterior symmetry	The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.	got7fsn_ti	specification of ureteric bud anterior/posterior asymmetry						mah	2010-02-10T02:18:16Z						biological_process											owl:Class	
GO:1990010	biolink:NamedThing	compound eye retinal cell apoptotic process	Any apoptotic process in a compound eye retinal cell.	got7fsn_ti							pr	2012-12-12T10:21:07Z						biological_process											owl:Class	
GO:0004100	biolink:NamedThing	chitin synthase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).	got7fsn_ti	UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity|chitin synthetase activity|chitin-uridine diphosphate acetylglucosaminyltransferase activity|chitin-UDP acetyl-glucosaminyl transferase activity|chitin-UDP N-acetylglucosaminyltransferase activity|trans-N-acetylglucosaminosylase activity											EC:2.4.1.16|RHEA:16637|MetaCyc:CHITIN-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0070410	biolink:NamedThing	co-SMAD binding	Binding to a common mediator SMAD signaling protein.	got7fsn_ti	common-partner SMAD binding|common partner SMAD binding|common mediator SMAD binding|common-mediator SMAD binding													molecular_function											owl:Class	
GO:0046056	biolink:NamedThing	dADP metabolic process	The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).	got7fsn_ti	dADP metabolism													biological_process											owl:Class	
GO:0071293	biolink:NamedThing	cellular response to tellurium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.	got7fsn_ti	cellular response to tellurium						mah	2009-12-10T04:16:52Z						biological_process											owl:Class	
GO:0047397	biolink:NamedThing	dolichylphosphate-glucose phosphodiesterase activity	Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose.	got7fsn_ti	dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase activity|dolichyl-phosphate-glucose phosphodiesterase activity|Dol-P-Glc phosphodiesterase activity|dolichol phosphoglucose phosphodiesterase activity											EC:3.1.4.48|MetaCyc:3.1.4.48-RXN|RHEA:13857		molecular_function											owl:Class	
GO:0102174	biolink:NamedThing	4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O.	got7fsn_ti												MetaCyc:RXN-11927|RHEA:58864		molecular_function											owl:Class	
GO:0033402	biolink:NamedThing	UUC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UUC codon.	got7fsn_ti	phenylalanine tRNA|TTC codon-amino acid adaptor activity				Note that in the standard genetic code, TTC codes for phenylalanine.									molecular_function											owl:Class	
GO:0018571	biolink:NamedThing	2,3-dihydroxy-p-cumate dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.	got7fsn_ti	2,3-dihydroxy-p-cumate 3,4-dioxygenase|2,3-dihydroxy-p-cumate-3,4-dioxygenase											MetaCyc:RXN-666|UM-BBD_reactionID:r0397|RHEA:42568		molecular_function											owl:Class	
GO:0070575	biolink:NamedThing	peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation	The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.	got7fsn_ti	peptide mating pheromone formation involved in pheromone-induced unidirectional conjugation|peptide mating pheromone processing involved in pheromone-induced unidirectional conjugation						mah	2009-04-20T04:32:07Z						biological_process											owl:Class	
GO:0102320	biolink:NamedThing	1,8-cineole 2-exo-monooxygenase activity	Catalysis of the reaction: 1,8-cineole + NADPH + H+ + O2 <=> 2-exo-hydroxy-1,8-cineole + NADP + H2O.	got7fsn_ti												RHEA:32895|EC:1.14.14.56|MetaCyc:RXN-13133		molecular_function											owl:Class	
GO:0043778	biolink:NamedThing	cobalt-precorrin-8 methylmutase activity	Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate.	got7fsn_ti	cobalt-precorrin 8 methylmutase activity|cobalt-precorrin 8X methylmutase activity|cobalt-precorrin-8X methylmutase activity											EC:5.4.99.60|MetaCyc:RXN-8768|RHEA:16209		molecular_function											owl:Class	
GO:0103008	biolink:NamedThing	4-chloro-2-methylphenoxyacetate oxygenase activity	Catalysis of the reaction: 4-chloro-2-methylphenoxyacetate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + 2-oxo monocarboxylic acid anion + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-9864		molecular_function											owl:Class	
GO:0047932	biolink:NamedThing	glucosamine N-acetyltransferase activity	Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H(+).	got7fsn_ti	glucosamine acetylase activity|acetyl-CoA:D-glucosamine N-acetyltransferase activity|glucosamine acetyltransferase activity											RHEA:21332|EC:2.3.1.3|MetaCyc:GLUCOSAMINE-N-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R01204		molecular_function											owl:Class	
GO:0033950	biolink:NamedThing	xyloglucan-specific exo-beta-1,4-glucanase activity	Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.	got7fsn_ti	[(1->6)-alpha-D-xylo]-(1->4)-beta-D-glucan exo-glucohydrolase activity|Cel74A											MetaCyc:3.2.1.155-RXN|EC:3.2.1.155		molecular_function											owl:Class	
GO:0061755	biolink:NamedThing	positive regulation of circulating fibrinogen levels	Any process that increases the quantity of fibrinogen circulating in the bloodstream.	got7fsn_ti							dph	2016-02-29T16:26:49Z						biological_process											owl:Class	
GO:0102075	biolink:NamedThing	OPC4-trans-2-enoyl-CoA hydratase activity	Catalysis of the reaction: OPC4-3-hydroxyacyl-CoA <=> OPC4-trans-2-enoyl-CoA + H2O.	got7fsn_ti												MetaCyc:RXN-10705		molecular_function											owl:Class	
GO:0042751	biolink:NamedThing	estivation	Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season.	got7fsn_ti	aestivation											Wikipedia:Estivation		biological_process											owl:Class	
GO:1900054	biolink:NamedThing	positive regulation of retinoic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process.	got7fsn_ti	upregulation of retinoic acid biosynthetic process|up regulation of retinoic acid biosynthetic process|activation of retinoic acid biosynthetic process|positive regulation of retinoic acid anabolic process|up-regulation of retinoic acid biosynthetic process|up regulation of retinoic acid anabolic process|up-regulation of retinoic acid anabolic process|upregulation of retinoic acid anabolic process|activation of retinoic acid anabolic process						yaf	2012-01-20T09:55:52Z						biological_process											owl:Class	
GO:0046136	biolink:NamedThing	positive regulation of vitamin metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	got7fsn_ti	stimulation of vitamin metabolic process|activation of vitamin metabolic process|up regulation of vitamin metabolic process|up-regulation of vitamin metabolic process|positive regulation of vitamin metabolism|upregulation of vitamin metabolic process													biological_process											owl:Class	
GO:0000296	biolink:NamedThing	spermine transport	The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0097576	biolink:NamedThing	vacuole fusion	Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.	got7fsn_ti							pr	2014-02-28T09:49:31Z						biological_process											owl:Class	
GO:0102898	biolink:NamedThing	levopimaradienol hydroxylase activity	Catalysis of the reaction: H+ + levopimaradienol + NADPH + O2 <=> levopiramadiene-diol + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-8517		molecular_function											owl:Class	
GO:0102329	biolink:NamedThing	hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA reductase activity	Catalysis of the reaction: 16-hydroxy-hentriaconta-3,6,9,12,19,22,25,28-octaene-15-oyl-CoA + NADP <=> hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-13251		molecular_function											owl:Class	
GO:0102661	biolink:NamedThing	homogentisate solanyltransferase activity	Catalysis of the reaction: all-trans-nonaprenyl diphosphate + homogentisate + H+ <=> 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinone + carbon dioxide + diphosphoric acid.	got7fsn_ti												RHEA:37995|EC:2.5.1.117|MetaCyc:RXN-2761		molecular_function											owl:Class	
GO:0050307	biolink:NamedThing	sucrose-phosphate phosphatase activity	Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate.	got7fsn_ti	sucrose-phosphate phosphohydrolase activity|sucrose-6F-phosphate phosphohydrolase activity											KEGG_REACTION:R00805|MetaCyc:SUCROSE-PHOSPHATASE-RXN|KEGG_REACTION:R06211|EC:3.1.3.24|RHEA:19289		molecular_function											owl:Class	
GO:0044574	biolink:NamedThing	starch utilization system complex assembly	The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan.	got7fsn_ti	assembly of starch utilization system complex|SUS complex assembly						jl	2012-04-19T03:40:24Z						biological_process											owl:Class	
GO:0042211	biolink:NamedThing	dimethylsilanediol catabolic process	The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.	got7fsn_ti	dimethylsilanediol breakdown|dimethylsilanediol degradation|dimethylsilanediol catabolism|degradation of dimethylsilanediol|catabolic process of DMSD|catabolism of DMSD													biological_process											owl:Class	
GO:0046254	biolink:NamedThing	anaerobic toluene catabolic process	The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.	got7fsn_ti	anaerobic toluene breakdown|anaerobic toluene catabolism|anaerobic toluene degradation											MetaCyc:PWY-81		biological_process											owl:Class	
GO:0050008	biolink:NamedThing	isopiperitenone delta-isomerase activity	Catalysis of the reaction: isopiperitenone = piperitenone.	got7fsn_ti	isopiperitenone delta8-delta4-isomerase activity|isopiperitenone D-isomerase activity											MetaCyc:ISOPIPERITENONE-DELTA-ISOMERASE-RXN|EC:5.3.3.11|RHEA:21516|KEGG_REACTION:R03782		molecular_function											owl:Class	
GO:0001048	biolink:NamedThing	RNA polymerase IV core binding	Binding to RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production.	got7fsn_ti							krc	2010-09-23T01:41:03Z						molecular_function											owl:Class	
GO:0008909	biolink:NamedThing	isochorismate synthase activity	Catalysis of the reaction: chorismate = isochorismate.	got7fsn_ti	isochorismate synthetase activity|isochorismate hydroxymutase activity|isochorismate mutase activity				Note that this function was formerly EC:5.4.99.6.							RHEA:18985|MetaCyc:ISOCHORSYN-RXN|EC:5.4.4.2|KEGG_REACTION:R01717		molecular_function											owl:Class	
GO:0050568	biolink:NamedThing	protein-glutamine glutaminase activity	Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3.	got7fsn_ti	destabilase activity|peptidoglutaminase II activity|glutaminyl-peptide glutaminase activity|glutaminylpeptide glutaminase activity|protein-L-glutamine amidohydrolase activity|peptidylglutaminase II											RHEA:16441|EC:3.5.1.44|MetaCyc:CHEBDEAMID-RXN		molecular_function											owl:Class	
GO:0036210	biolink:NamedThing	protein modification process in other organism	The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).	got7fsn_ti	protein modification in other organism						bf	2012-04-26T01:29:29Z						biological_process											owl:Class	
GO:0061213	biolink:NamedThing	positive regulation of mesonephros development	Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti							dph	2010-08-17T03:39:35Z						biological_process											owl:Class	
GO:0072689	biolink:NamedThing	MCM complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication.	got7fsn_ti							mah	2011-08-12T10:57:29Z						biological_process											owl:Class	
GO:1900840	biolink:NamedThing	regulation of helvolic acid biosynthetic process	Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process.	got7fsn_ti							di	2012-06-07T09:38:33Z						biological_process											owl:Class	
GO:0018113	biolink:NamedThing	lysine racemase activity	Catalysis of the reaction: L-lysine = D-lysine.	got7fsn_ti												EC:5.1.1.5|MetaCyc:LYSINE-RACEMASE-RXN|RHEA:22864		molecular_function											owl:Class	
GO:0017018	biolink:NamedThing	myosin phosphatase activity	Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.	got7fsn_ti	myosin phosphatase, intrinsic catalyst activity|myosin phosphatase myosin binding										GO:0017019	Reactome:R-HSA-390593|Reactome:R-HSA-445699		molecular_function											owl:Class	
GO:0047118	biolink:NamedThing	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity	Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH.	got7fsn_ti	2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|2,6-dioxo-6-phenylhexanoate:NADP+ delta2-oxidoreductase activity											KEGG_REACTION:R03463|RHEA:24268|MetaCyc:1.3.1.40-RXN|EC:1.3.1.40		molecular_function											owl:Class	
GO:0033510	biolink:NamedThing	luteolin metabolic process	The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.	got7fsn_ti	luteolin metabolism													biological_process											owl:Class	
GO:0018662	biolink:NamedThing	phenol 2-monooxygenase activity	Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O.	got7fsn_ti	phenol,NADPH:oxygen oxidoreductase (2-hydroxylating)|phenol hydroxylase activity|phenol o-hydroxylase activity											EC:1.14.13.7|UM-BBD_enzymeID:e0208|MetaCyc:PHENOL-2-MONOOXYGENASE-RXN|RHEA:17061		molecular_function											owl:Class	
GO:0047104	biolink:NamedThing	hexadecanal dehydrogenase (acylating) activity	Catalysis of the reaction: CoA + NAD(+) + palmitaldehyde = H(+) + NADH + palmitoyl-CoA.	got7fsn_ti	hexadecanal:NAD+ oxidoreductase (CoA-acylating)|fatty acyl-CoA reductase activity											RHEA:19705|KEGG_REACTION:R01277|EC:1.2.1.42|MetaCyc:1.2.1.42-RXN|UM-BBD_reactionID:r1374		molecular_function											owl:Class	
GO:0051060	biolink:NamedThing	pullulanase activity	Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.	got7fsn_ti	limit dextrinase|debranching enzyme activity|bacterial debranching enzyme|pullulan alpha-1,6-glucanohydrolase activity|R-enzyme|alpha-dextrin endo-1,6-alpha-glucosidase activity|amylopectin 6-glucanohydrolase activity|pullulan 6-glucanohydrolase activity											EC:3.2.1.41|MetaCyc:RXN-1824		molecular_function											owl:Class	
GO:0035375	biolink:NamedThing	zymogen binding	Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.	got7fsn_ti	proenzyme binding						bf	2010-03-18T10:50:35Z						molecular_function											owl:Class	
GO:0035612	biolink:NamedThing	AP-2 adaptor complex binding	Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).	got7fsn_ti	AP-2 clathrin adaptor complex binding						bf	2010-11-25T03:51:17Z						molecular_function											owl:Class	
GO:0071939	biolink:NamedThing	vitamin A import	The directed movement of vitamin A into a cell or organelle. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.	got7fsn_ti	vitamin A uptake						mah	2010-09-30T04:36:22Z						biological_process											owl:Class	
GO:0102191	biolink:NamedThing	4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol dehydrogenase/C4-decarboxylase activity	Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) <=> 5alpha-cholesta-7,24-dien-3-one + NADH(2-) + carbon dioxide.	got7fsn_ti												EC:1.1.1.418|RHEA:59016|MetaCyc:RXN-11959		molecular_function											owl:Class	
GO:0047371	biolink:NamedThing	butyrate-acetoacetate CoA-transferase activity	Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.	got7fsn_ti	butyryl-CoA-acetoacetate CoA-transferase activity|butanoyl-CoA:acetoacetate CoA-transferase activity|butyryl coenzyme A-acetoacetate coenzyme A-transferase activity											RHEA:12961|KEGG_REACTION:R01365|EC:2.8.3.9|MetaCyc:2.8.3.9-RXN		molecular_function											owl:Class	
GO:0048381	biolink:NamedThing	lateral mesoderm structural organization	The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	lateral mesoderm structural organisation|lateral plate mesoderm structural organization													biological_process											owl:Class	
GO:0047773	biolink:NamedThing	carnitinamidase activity	Catalysis of the reaction: (R)-carnitinamide + H(2)O = (R)-carnitine + NH(4)(+).	got7fsn_ti	L-carnitine amidase activity|carnitine amidase activity|L-carnitinamide amidohydrolase activity|L-carnitinamidase activity											MetaCyc:CARNITINAMIDASE-RXN|RHEA:17537|EC:3.5.1.73|KEGG_REACTION:R01922		molecular_function											owl:Class	
GO:0047068	biolink:NamedThing	N5,N10-methenyltetrahydromethanopterin hydrogenase activity	Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H(+).	got7fsn_ti	H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity|H2-dependent methylene-H4MPT dehydrogenase activity|hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase activity|5,10-methenyltetrahydromethanopterin hydrogenase activity|hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase activity|hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase activity|H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase activity|nonmetal hydrogenase activity|H(2)-dependent methylene-H(4)MPT dehydrogenase activity|N5,N10-methylenetetrahydromethanopterin dehydrogenase activity|N(5),N(10)-methenyltetrahydromethanopterin hydrogenase activity										GO:0016947	EC:1.12.98.2|RHEA:20017|KEGG_REACTION:R04455|MetaCyc:H2-METHYLENE-THMPT-DEHYDRO-RXN		molecular_function											owl:Class	
GO:0010355	biolink:NamedThing	homogentisate farnesyltransferase activity	Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol.	got7fsn_ti														molecular_function											owl:Class	
GO:0019159	biolink:NamedThing	nicotinamide-nucleotide amidase activity	Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3.	got7fsn_ti	NMN amidohydrolase|nicotinamide-D-ribonucleotide amidohydrolase activity|nicotinamide mononucleotide amidohydrolase activity|NMN deamidase activity|nicotinamide mononucleotide deamidase activity											MetaCyc:NMNAMIDOHYDRO-RXN|RHEA:12400|EC:3.5.1.42		molecular_function											owl:Class	
GO:0019560	biolink:NamedThing	histidine catabolic process to hydantoin-5-propionate	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.	got7fsn_ti	histidine degradation to hydantoin-5-propionate|histidine breakdown to hydantoin-5-propionate											MetaCyc:HISHP-PWY		biological_process											owl:Class	
GO:0032067	biolink:NamedThing	type IV site-specific deoxyribonuclease activity	Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).	got7fsn_ti	type IV restriction enzyme activity													molecular_function											owl:Class	
GO:0018478	biolink:NamedThing	malonate-semialdehyde dehydrogenase (acetylating) activity	Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+.	got7fsn_ti	malonic semialdehyde oxidative decarboxylase activity|3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating)											EC:1.2.1.18|RHEA:22988|MetaCyc:1.2.1.18-RXN		molecular_function											owl:Class	
GO:0002486	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.	got7fsn_ti	endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-independent|TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway|TAP-independent endogenous peptide antigen processing and presentation via MHC class I via ER pathway													biological_process											owl:Class	
GO:0033257	biolink:NamedThing	Bcl3/NF-kappaB2 complex	A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.	got7fsn_ti	Bcl3-p52 complex|Bcl3-NFKB2 complex													cellular_component											owl:Class	
GO:0033256	biolink:NamedThing	I-kappaB/NF-kappaB complex	A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.	got7fsn_ti														cellular_component											owl:Class	
GO:0102410	biolink:NamedThing	quercetin-4',3-O-glucosyltransferase activity	Catalysis of the reaction: quercetin 4'-O-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-).	got7fsn_ti												MetaCyc:RXN-13765		molecular_function											owl:Class	
GO:0043702	biolink:NamedThing	carotenoid vesicle	A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.	got7fsn_ti														cellular_component											owl:Class	
GO:0102572	biolink:NamedThing	N-glutamylanilide hydrolase activity	Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+.	got7fsn_ti												MetaCyc:RXN-15251|RHEA:50684		molecular_function											owl:Class	
GO:0033929	biolink:NamedThing	blood-group-substance endo-1,4-beta-galactosidase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.	got7fsn_ti	blood-group-substance 1,4-beta-D-galactanohydrolase activity|endo-beta-galactosidase activity											MetaCyc:3.2.1.102-RXN|EC:3.2.1.102		molecular_function											owl:Class	
GO:0004039	biolink:NamedThing	allophanate hydrolase activity	Catalysis of the reaction: H(2)O + 3 H(+) + urea-1-carboxylate = 2 CO(2) + 2 NH(4)(+).	got7fsn_ti	allophanate lyase activity|urea-1-carboxylate amidohydrolase activity											MetaCyc:ALLOPHANATE-HYDROLASE-RXN|UM-BBD_reactionID:r0848|KEGG_REACTION:R00005|EC:3.5.1.54|RHEA:19029		molecular_function											owl:Class	
GO:0061587	biolink:NamedThing	transfer RNA gene-mediated silencing	The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes.	got7fsn_ti	transfer RNA gene-mediated gene silencing|tRNA gene-mediated gene silencing|transfer RNA gene-mediated chromatin silencing|tRNA gene-mediated chromatin silencing|tgm silencing	https://github.com/geneontology/go-ontology/issues/22060					dph	2014-02-05T09:03:59Z						biological_process											owl:Class	
GO:0050785	biolink:NamedThing	advanced glycation end-product receptor activity	Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).	got7fsn_ti	AGE receptor activity|RAGE activity													molecular_function											owl:Class	
GO:0019034	biolink:NamedThing	viral replication complex	Specific locations and structures in the virus infected cell involved in replicating the viral genome.	got7fsn_ti														cellular_component											owl:Class	
GO:1900583	biolink:NamedThing	o-orsellinic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid.	got7fsn_ti	o-orsellinic acid breakdown|o-orsellinic acid catabolism|o-orsellinic acid degradation						di	2012-05-15T06:48:04Z						biological_process											owl:Class	
GO:1990927	biolink:NamedThing	calcium ion regulated lysosome exocytosis	The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.	got7fsn_ti							sp	2016-02-16T14:19:44Z						biological_process											owl:Class	
GO:0003847	biolink:NamedThing	1-alkyl-2-acetylglycerophosphocholine esterase activity	Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate.	got7fsn_ti	LDL-associated phospholipase A2|platelet-activating factor acetylhydrolase activity|alkylacetyl-GPC:acetylhydrolase activity|1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase activity|2-acetyl-1-alkylglycerophosphocholine esterase activity|1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase activity|LDL-PLA(2) activity|PAF 2-acylhydrolase activity|PAF acetylhydrolase activity|LDL-PLA2|LDL-associated phospholipase A(2) activity											MetaCyc:3.1.1.47-RXN|Reactome:R-HSA-8869206|RHEA:17777|EC:3.1.1.47		molecular_function											owl:Class	
GO:0030546	biolink:NamedThing	signaling receptor activator activity	The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.	got7fsn_ti	receptor activator activity|signalling receptor activator activity													molecular_function											owl:Class	
GO:0046569	biolink:NamedThing	glyoxal oxidase activity	Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2.	got7fsn_ti	GLOX													molecular_function											owl:Class	
GO:0052758	biolink:NamedThing	coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity	Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.	got7fsn_ti	coenzyme F420-dependent 2,4,6-trinitrophenol hydride transferase activity|TNP reductase activity						ai	2011-09-28T11:06:03Z				UM-BBD_reactionID:r1065|EC:1.3.99.-		molecular_function											owl:Class	
GO:0099620	biolink:NamedThing	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate.	got7fsn_ti	UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase|UDP-L-Ara4N transaminase|UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase|UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase|UDP-Ara4O aminotransferase											EC:2.6.1.87|RHEA:24710		molecular_function											owl:Class	
GO:0018502	biolink:NamedThing	2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity	Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone.	got7fsn_ti												UM-BBD_reactionID:r0553|RHEA:15741|MetaCyc:LINC-RXN		molecular_function											owl:Class	
GO:0005873	biolink:NamedThing	plus-end kinesin complex	Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule.	got7fsn_ti														cellular_component											owl:Class	
GO:0070226	biolink:NamedThing	sulfur:ferric ion oxidoreductase activity	Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+.	got7fsn_ti	hydrogen sulfide:ferric ion oxidoreductase											MetaCyc:SULFFEOXIDO-RXN		molecular_function											owl:Class	
GO:0043811	biolink:NamedThing	phosphate:acyl-[acyl carrier protein] acyltransferase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein].	got7fsn_ti														molecular_function											owl:Class	
GO:1990769	biolink:NamedThing	proximal neuron projection	The portion of an axon or dendrite that is close to the neuronal cell body.	got7fsn_ti							sl	2015-06-10T20:30:40Z						cellular_component											owl:Class	
GO:1902795	biolink:NamedThing	heterochromatin domain assembly	The aggregation, arrangement and bonding together of a set of components to form a heterochromatin domain.	got7fsn_ti	HOOD formation|heterochromatin domain formation|HOOD assembly						mah	2014-03-24T12:46:56Z						biological_process											owl:Class	
GO:0098623	biolink:NamedThing	selenite reductase activity	Catalysis of the reaction: SeO3(2-) + 3NADPH + 5H+ = H2Se + 3NADP+ + 3H2O.	got7fsn_ti												Reactome:R-HSA-2408558		molecular_function											owl:Class	
GO:0035610	biolink:NamedThing	protein side chain deglutamylation	The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.	got7fsn_ti	shortening of glutamate side chain|removal of posttranslational polyglutamylation						bf	2010-11-18T01:09:03Z						biological_process											owl:Class	
GO:0018870	biolink:NamedThing	anaerobic 2-aminobenzoate metabolic process	The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen.	got7fsn_ti	anaerobic 2-aminobenzoate metabolism											UM-BBD_pathwayID:abz		biological_process											owl:Class	
GO:0035836	biolink:NamedThing	ergot alkaloid metabolic process	The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid.	got7fsn_ti	ergot alkaloid metabolism						bf	2011-05-04T03:23:13Z						biological_process											owl:Class	
GO:1990783	biolink:NamedThing	periphagosomal region of cytoplasm	Cytoplasm situated near, or occurring around, a phagosome.	got7fsn_ti							sl	2015-06-23T21:46:10Z						cellular_component											owl:Class	
GO:0036325	biolink:NamedThing	vascular endothelial growth factor receptor-3 signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-3 (VEGFR-3) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	VEGFR3 signaling pathway|FLT4 signaling pathway|VEGFR-3 signaling pathway						bf	2012-09-04T15:25:13Z						biological_process											owl:Class	
GO:0070034	biolink:NamedThing	telomerase RNA binding	Binding to the telomerase RNA template.	got7fsn_ti	TERC binding													molecular_function											owl:Class	
GO:0001537	biolink:NamedThing	N-acetylgalactosamine 4-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate.	got7fsn_ti	N-acetylgalactosamine 4-O-sulphotransferase activity											Reactome:R-HSA-3636919|Reactome:R-HSA-2022063|Reactome:R-HSA-6786034		molecular_function											owl:Class	
GO:0047046	biolink:NamedThing	homoisocitrate dehydrogenase activity	Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate.	got7fsn_ti	2-hydroxy-3-carboxyadipate dehydrogenase activity|3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating)|(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity|(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating)|3-carboxy-2-hydroxyadipate dehydrogenase activity|(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)|homoisocitric dehydrogenase activity|3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity				Note that EC:1.1.1.155 was merged into EC:1.1.1.87 as they are identical.						GO:0047984	RHEA:11900|EC:1.1.1.87|MetaCyc:1.1.1.87-RXN		molecular_function											owl:Class	
GO:0102496	biolink:NamedThing	GA5 2,3 epoxidase activity	Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A6 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-14327		molecular_function											owl:Class	
GO:0098686	biolink:NamedThing	hippocampal mossy fiber to CA3 synapse	One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.	got7fsn_ti							dos	2017-02-05T16:29:58Z						cellular_component											owl:Class	
GO:0002359	biolink:NamedThing	B-1 B cell proliferation	The expansion of a B-1 B cell by cell division. Follows B cell activation.	got7fsn_ti	B-1 B-cell proliferation|B-1 B-lymphocyte proliferation|B-1 B lymphocyte proliferation													biological_process											owl:Class	
GO:0018487	biolink:NamedThing	vanillate O-demethylase (anaerobic) activity	Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate.	got7fsn_ti												UM-BBD_reactionID:r0758		molecular_function											owl:Class	
GO:0050458	biolink:NamedThing	decylhomocitrate synthase activity	Catalysis of the reaction: 2-oxoglutarate + H(2)O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+).	got7fsn_ti	3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acylating) activity|dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)|2-decylhomocitrate synthase activity|3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)											KEGG_REACTION:R03859|EC:2.3.3.4|RHEA:10364|MetaCyc:DECYLHOMOCITRATE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0097048	biolink:NamedThing	dendritic cell apoptotic process	Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.	got7fsn_ti	dendritic cell apoptosis						pr	2011-05-04T02:18:59Z						biological_process											owl:Class	
GO:0031208	biolink:NamedThing	POZ domain binding	Binding to a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors.	got7fsn_ti	BTB domain|broad-complex, tramtrack, and bric-a-brac domain binding													molecular_function											owl:Class	
GO:0018736	biolink:NamedThing	6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity	Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r0206		molecular_function											owl:Class	
GO:0071488	biolink:NamedThing	cellular response to very low light intensity stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.	got7fsn_ti							mah	2009-12-18T02:13:40Z						biological_process											owl:Class	
GO:0036227	biolink:NamedThing	mitotic G2 cell cycle arrest in response to glucose starvation	The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose.	got7fsn_ti							bf	2012-05-09T02:45:49Z						biological_process											owl:Class	
GO:0047842	biolink:NamedThing	dehydro-L-gulonate decarboxylase activity	Catalysis of the reaction: 3-dehydro-L-gulonate + H(+) = L-xylulose + CO(2).	got7fsn_ti	keto-L-gulonate decarboxylase activity|3-dehydro-L-gulonate carboxy-lyase activity|3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming)|3-keto-L-gulonate decarboxylase activity											MetaCyc:DEHYDRO-L-GULONATE-DECARBOXYLASE-RXN|Reactome:R-HSA-5662473|EC:4.1.1.34|KEGG_REACTION:R01905|RHEA:11084		molecular_function											owl:Class	
GO:0052594	biolink:NamedThing	aminoacetone:oxygen oxidoreductase(deaminating) activity	Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+.	got7fsn_ti												MetaCyc:AMACETOXID-RXN|RHEA:28186|KEGG_REACTION:R02529|EC:1.4.3.21		molecular_function											owl:Class	
GO:0043464	biolink:NamedThing	malolactic fermentation	The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP.	got7fsn_ti	L-malate fermentation|malo-lactate fermentation|malate fermentation|malolactate fermentation											Wikipedia:Malolactic_fermentation		biological_process											owl:Class	
GO:0070690	biolink:NamedThing	L-threonine catabolic process to acetyl-CoA	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA.	got7fsn_ti	L-threonine degradation to acetyl-CoA|L-threonine breakdown to acetyl-CoA|L-threonine catabolism to acetyl-CoA|threonine catabolic process to acetyl-CoA						mah	2009-06-03T01:40:22Z				MetaCyc:PWY-5436		biological_process											owl:Class	
GO:0042137	biolink:NamedThing	sequestering of neurotransmitter	The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system.	got7fsn_ti	neurotransmitter sequestration|sequestration of neurotransmitter|retention of neurotransmitter|neurotransmitter biosynthetic process and storage|neurotransmitter biosynthesis and storage|neurotransmitter retention|neurotransmitter storage|storage of neurotransmitter													biological_process											owl:Class	
GO:0047308	biolink:NamedThing	alanine-oxomalonate transaminase activity	Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate.	got7fsn_ti	alanine-oxomalonate aminotransferase activity|L-alanine:oxomalonate aminotransferase activity|alanine--oxomalonate aminotransferase activity|L-alanine-ketomalonate transaminase activity|alanine-ketomalonate (mesoxalate) transaminase activity											KEGG_REACTION:R02970|RHEA:18809|MetaCyc:2.6.1.47-RXN|EC:2.6.1.47		molecular_function											owl:Class	
GO:0097362	biolink:NamedThing	MCM8-MCM9 complex	A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.	got7fsn_ti							pr	2012-07-20T02:10:12Z						cellular_component											owl:Class	
GO:0052725	biolink:NamedThing	inositol-1,3,4-trisphosphate 6-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+).	got7fsn_ti	ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase activity|IP3 6-kinase activity|Ins(1,3,4)P3 6-kinase activity|inositol-trisphosphate 6-kinase activity|inositol 1,3,4-trisphosphate 6-kinase activity|1D-myo-inositol-trisphosphate 6-kinase activity|ins(1,3,4)P(3) 6-kinase activity						ai	2011-08-16T12:42:59Z				Reactome:R-HSA-1855197|EC:2.7.1.159|MetaCyc:2.7.1.133-RXN|RHEA:20940|Reactome:R-HSA-2267372		molecular_function											owl:Class	
GO:0002333	biolink:NamedThing	transitional one stage B cell differentiation	The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21.	got7fsn_ti	transitional one stage B cell development|transitional one stage B-lymphocyte differentiation|transitional one stage B-cell differentiation|transitional one stage B lymphocyte differentiation|T1 stage B cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0018509	biolink:NamedThing	cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity	Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.	got7fsn_ti	biphenyl-2,3-dihydro-2,3-diol dehydrogenase activity|2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase activity|cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase activity											MetaCyc:1.3.1.56-RXN|RHEA:17033|UM-BBD_enzymeID:e0134|EC:1.3.1.56		molecular_function											owl:Class	
GO:0047092	biolink:NamedThing	27-hydroxycholesterol 7-alpha-monooxygenase activity	Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol.	got7fsn_ti	27-hydroxycholesterol 7alpha-monooxygenase activity|27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)|27-hydroxycholesterol 7a-hydroxylase activity|27-hydroxycholesterol 7alpha-hydroxylase activity|27-hydroxycholesterol 7-alpha-hydroxylase activity											MetaCyc:1.14.13.60-RXN|RHEA:24308|EC:1.14.14.29		molecular_function											owl:Class	
GO:0002126	biolink:NamedThing	instrumental aggressive behavior	Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation.	got7fsn_ti	instrumental aggression													biological_process											owl:Class	
GO:0061832	biolink:NamedThing	basal ectoplasmic specialization	Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell.	got7fsn_ti	basal ES													cellular_component											owl:Class	
GO:0034361	biolink:NamedThing	very-low-density lipoprotein particle	A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.	got7fsn_ti	VLDL complex|very-low-density lipoprotein complex|VLDL particle													cellular_component											owl:Class	
GO:0000172	biolink:NamedThing	ribonuclease MRP complex	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.	got7fsn_ti	ribonuclease mitochondrial RNA processing complex|RNase MRP complex													cellular_component											owl:Class	
GO:0010736	biolink:NamedThing	serum response element binding	Binding to a serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.	got7fsn_ti					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.									molecular_function											owl:Class	
GO:0102302	biolink:NamedThing	mycinamicin VI 2''-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + mycinamicin VI <=> S-adenosyl-L-homocysteine  + mycinamicin III(1+) + H+.	got7fsn_ti												MetaCyc:RXN-12801|RHEA:31643|EC:2.1.1.238		molecular_function											owl:Class	
GO:0008231	biolink:NamedThing	repressor ecdysone receptor complex	A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes.	got7fsn_ti	repressor ecdysone receptor holocomplex													cellular_component											owl:Class	
GO:0047406	biolink:NamedThing	beta-aspartyl-N-acetylglucosaminidase activity	Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-D-glucosamine + L-asparagine.	got7fsn_ti	1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase activity|beta-aspartylacetylglucosaminidase activity											KEGG_REACTION:R01266|MetaCyc:3.2.2.11-RXN|EC:3.2.2.11|RHEA:12324		molecular_function											owl:Class	
GO:1904666	biolink:NamedThing	regulation of ubiquitin protein ligase activity	Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity.	got7fsn_ti	regulation of protein ubiquitination activity|regulation of APC-fizzy related complex activity|regulation of ubiquitin ligase activity|regulation of E3						dph	2015-09-08T15:26:59Z			GO:1903834			biological_process											owl:Class	
GO:0051438	biolink:NamedThing	regulation of ubiquitin-protein transferase activity	Any process that modulates the frequency, rate or extent of ubiquitin transferase activity.	got7fsn_ti	ubiquitin transferase regulator|anaphase-promoting complex regulator|ubiquitin-protein transferase regulator|APC regulator|SCF complex regulator|regulation of ubiquitin transferase activity													biological_process											owl:Class	
GO:0102692	biolink:NamedThing	benzyladenine UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + N-benzyl-9-(alpha-D-glucosyl)adenine + UDP.	got7fsn_ti												MetaCyc:RXN-4730		molecular_function											owl:Class	
GO:0048061	biolink:NamedThing	positive gravitaxis	The directed movement of a motile cell or organism towards the source of gravity.	got7fsn_ti	positive taxis in response to gravitytaxis in response to gravitational stimulus|positive geotactic behavior|positive geotactic behaviour|positive gravitactic behaviour|positive taxis in response to gravity|positive gravitactic behavior										GO:0048064			biological_process											owl:Class	
GO:0102525	biolink:NamedThing	2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity	Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide.	got7fsn_ti												EC:1.14.11.41|RHEA:36607|MetaCyc:RXN-14542		molecular_function											owl:Class	
GO:0033553	biolink:NamedThing	rDNA heterochromatin	A region of heterochromatin located at the rDNA repeats in a chromosome.	got7fsn_ti	ribosomal DNA heterochromatin of nucleus|ribosomal DNA heterochromatin of cell nucleus|nuclear rDNA heterochromatin|ribosomal DNA heterochromatin										GO:1902377			cellular_component											owl:Class	
GO:0047789	biolink:NamedThing	creatininase activity	Catalysis of the reaction: creatinine + H(2)O = creatine.	got7fsn_ti	creatinine amidohydrolase activity|creatinine hydrolase											EC:3.5.2.10|RHEA:14533|MetaCyc:CREATININASE-RXN|KEGG_REACTION:R01884		molecular_function											owl:Class	
GO:0005122	biolink:NamedThing	torso binding	Binding to a torso (tor) protein, a receptor tyrosine kinase.	got7fsn_ti	torso ligand|tor ligand|tor binding													molecular_function											owl:Class	
GO:0003834	biolink:NamedThing	beta-carotene 15,15'-dioxygenase activity	Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.	got7fsn_ti	carotene dioxygenase activity|beta-carotene 15,15'-monooxygenase activity|carotene 15,15'-dioxygenase activity	https://github.com/geneontology/go-ontology/issues/21765			Formerly EC:1.13.11.n2, EC:1.13.11.21 and then EC 1.14.99.36.							RHEA:32887|MetaCyc:BETA-CAROTENE-1515-DIOXYGENASE-RXN|KEGG_REACTION:R00032|EC:1.13.11.63|Reactome:R-HSA-975635		molecular_function											owl:Class	
GO:0072574	biolink:NamedThing	hepatocyte proliferation	The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.	got7fsn_ti							mah	2011-02-02T03:34:49Z						biological_process											owl:Class	
GO:0072575	biolink:NamedThing	epithelial cell proliferation involved in liver morphogenesis	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.	got7fsn_ti							mah	2011-02-02T03:37:50Z						biological_process											owl:Class	
GO:0047937	biolink:NamedThing	glucose-1-phosphate phosphodismutase activity	Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate.	got7fsn_ti	phosphodismutase activity|glucose 1-phosphate transphosphorylase activity|D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity											MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN|RHEA:16397|EC:2.7.1.41		molecular_function											owl:Class	
GO:0042207	biolink:NamedThing	styrene catabolic process	The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.	got7fsn_ti	styrene breakdown|styrene catabolism|styrene degradation											UM-BBD_pathwayID:sty		biological_process											owl:Class	
GO:0032003	biolink:NamedThing	interleukin-28 receptor binding	Binding to an interleukin-28 receptor.	got7fsn_ti	interleukin-28 receptor ligand|IL-28													molecular_function											owl:Class	
GO:1990481	biolink:NamedThing	mRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.	got7fsn_ti	mRNA pseudouridylation						mcc	2014-09-12T15:13:39Z						biological_process											owl:Class	
GO:0001714	biolink:NamedThing	endodermal cell fate specification	The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	got7fsn_ti	endoderm cell fate specification													biological_process											owl:Class	
GO:0034811	biolink:NamedThing	benzo(a)pyrene 9,10-dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol.	got7fsn_ti												UM-BBD_reactionID:r1132|EC:1.13.11.-		molecular_function											owl:Class	
GO:0140365	biolink:NamedThing	RNP body	A ribonucleoprotein granule located in the cytoplasm of bacteria, minimally containing the RNase E protein and RNA molecules. Bacterial RNP-bodies are similar to eukaryotic P-bodies and stress granules.	got7fsn_ti	BR-body						pg	2019-07-25T19:31:17Z						cellular_component											owl:Class	
GO:0060305	biolink:NamedThing	regulation of cell diameter	Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell.	got7fsn_ti	regulation of cell width													biological_process											owl:Class	
GO:0018700	biolink:NamedThing	2-chloro-N-isopropylacetanilide reductive dehalogenase activity	Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide.	got7fsn_ti												EC:1.97.1.-|UM-BBD_reactionID:r0719		molecular_function											owl:Class	
GO:0035339	biolink:NamedThing	SPOTS complex	A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.	got7fsn_ti	serine palmitoyltransferase, Orm1/2, Tsc3 and Sac1 complex						bf	2010-03-03T10:28:42Z						cellular_component											owl:Class	
GO:0030507	biolink:NamedThing	spectrin binding	Binding to spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.	got7fsn_ti														molecular_function											owl:Class	
GO:0102846	biolink:NamedThing	1-18:3-2-16:1-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8308		molecular_function											owl:Class	
GO:0034004	biolink:NamedThing	germacradienol synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.	got7fsn_ti	2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming] activity											KEGG_REACTION:R07647|RHEA:22436|MetaCyc:RXN-8648|EC:4.2.3.22		molecular_function											owl:Class	
GO:0061801	biolink:NamedThing	laminin-5B complex	A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains.	got7fsn_ti	laminin 3B32 complex						dph	2016-10-26T15:05:15Z						cellular_component											owl:Class	
GO:0102630	biolink:NamedThing	gossypetin 8-methyl ester 3'-O-methyltransferase activity	Catalysis of the reaction: 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate + S-adenosyl-L-methionine  <=> gossypetin 3',8-dimethyl ether + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-15536		molecular_function											owl:Class	
GO:0102443	biolink:NamedThing	L-2-hydroxycarboxylate dehydrogenase (NAD+) activity	Catalysis of the reaction: NAD(1-) + a (2S)-2-hydroxycarboxylate <=> NADH(2-) + H+ + a 2-oxo carboxylate.	got7fsn_ti												MetaCyc:RXN-13927|EC:1.1.1.337|RHEA:34555		molecular_function											owl:Class	
GO:0060075	biolink:NamedThing	regulation of resting membrane potential	Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.	got7fsn_ti	regulation of resting potential													biological_process											owl:Class	
GO:0019247	biolink:NamedThing	lactate racemization	Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.	got7fsn_ti														biological_process											owl:Class	
GO:0098746	biolink:NamedThing	fast, calcium ion-dependent exocytosis of neurotransmitter	The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.	got7fsn_ti	synchronous, calcium ion-dependent exocytosis of neurotransmitter													biological_process											owl:Class	
GO:0033911	biolink:NamedThing	mycodextranase activity	Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds.	got7fsn_ti	1,3-1,4-alpha-D-glucan 4-glucanohydrolase activity											EC:3.2.1.61|MetaCyc:3.2.1.61-RXN		molecular_function											owl:Class	
GO:0051612	biolink:NamedThing	negative regulation of serotonin uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.	got7fsn_ti	down regulation of serotonin uptake|down-regulation of serotonin uptake|negative regulation of 5-hydroxytryptamine uptake|negative regulation of serotonin import|downregulation of serotonin uptake|negative regulation of 5-HT uptake|negative regulation of 5HT uptake													biological_process											owl:Class	
GO:1905348	biolink:NamedThing	endonuclease complex	A protein complex which is capable of endonuclease activity.	got7fsn_ti					An example of this is MUS81 in human (Q96NY9) in PMID:18413719 (inferred from direct assay).		bhm	2016-08-03T12:27:00Z						cellular_component											owl:Class	
GO:0043863	biolink:NamedThing	4-hydroxy-2-ketopimelate aldolase activity	Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate.	got7fsn_ti	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase activity|HpcH|HHED aldolase activity|HpaI											RHEA:25788|MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN		molecular_function											owl:Class	
GO:0030367	biolink:NamedThing	interleukin-17 receptor binding	Binding to an interleukin-17 receptor.	got7fsn_ti	interleukin-17 receptor ligand|IL-17													molecular_function											owl:Class	
GO:0004339	biolink:NamedThing	glucan 1,4-alpha-glucosidase activity	Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.	got7fsn_ti	exo-1,4-alpha-glucosidase activity|lysosomal alpha-glucosidase activity|gamma-amylase activity|gamma-1,4-glucan glucohydrolase activity|glucose amylase activity|glucoamylase activity|1,4-alpha-D-glucan glucohydrolase activity|amyloglucosidase activity				Note that this term is not a child of 'alpha-glucosidase activity ; GO:0090599', because in the reaction represented by GO:0004339 results in the release of beta-D-glucose, whereas in GO:0090599 alpha-D-glucose is released.							EC:3.2.1.3|MetaCyc:3.2.1.3-RXN		molecular_function											owl:Class	
GO:0034022	biolink:NamedThing	3-(hydroxyamino)phenol mutase activity	Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone.	got7fsn_ti	3HAP mutase activity|3-hydroxylaminophenol mutase activity|3-(hydroxyamino)phenol hydroxymutase activity											MetaCyc:5.4.4.3-RXN|RHEA:20577|EC:5.4.4.3|KEGG_REACTION:R06988|UM-BBD_enzymeID:e0953		molecular_function											owl:Class	
GO:0047776	biolink:NamedThing	citramalate lyase activity	Catalysis of the reaction: S-citramalate = acetate + pyruvate.	got7fsn_ti	(+)-citramalate pyruvate-lyase activity|(3S)-citramalate pyruvate-lyase (acetate-forming)|citramalate synthetase activity|citramalate pyruvate lyase activity|(S)-citramalate lyase activity|citramalic synthase activity|(3S)-citramalate pyruvate-lyase activity|citramalic-condensing enzyme|citramalate pyruvate-lyase activity											MetaCyc:CITRAMALATE-LYASE-RXN|RHEA:15545|KEGG_REACTION:R00325|EC:4.1.3.22		molecular_function											owl:Class	
GO:0050553	biolink:NamedThing	taxadiene synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene.	got7fsn_ti	geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming)|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene-forming)|taxa-4(5),11(12)-diene synthase activity											RHEA:20912|KEGG_REACTION:R06305|EC:4.2.3.17|MetaCyc:4.2.3.17-RXN		molecular_function											owl:Class	
GO:0060758	biolink:NamedThing	foraging behavior by probing substrate	Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.	got7fsn_ti							dph	2009-06-22T02:53:09Z						biological_process											owl:Class	
GO:0043491	biolink:NamedThing	protein kinase B signaling	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.	got7fsn_ti	PKB signalling cascade|PKB signaling cascade|AKT signaling|AKT signalling cascade|AKT signal transduction|protein kinase B signaling cascade|protein kinase B signal transduction|AKT signaling cascade|PKB signal transduction|protein kinase B signalling cascade|PKB signaling													biological_process											owl:Class	
GO:0034849	biolink:NamedThing	2-naphthoate CoA-transferase activity	Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH.	got7fsn_ti												UM-BBD_reactionID:r1262		molecular_function											owl:Class	
GO:0052731	biolink:NamedThing	phosphocholine phosphatase activity	Catalysis of the reaction: choline phosphate + H2O = choline + phosphate.	got7fsn_ti	PHOSPHO1|phosphoethanolamine phosphohydrolase activity|3X11A						ai	2011-08-16T04:09:06Z				Reactome:R-HSA-1483159|MetaCyc:RXN-5647|KEGG_REACTION:R06871|RHEA:10492|EC:3.1.3.75		molecular_function											owl:Class	
GO:0044778	biolink:NamedThing	meiotic DNA integrity checkpoint signaling	A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.	got7fsn_ti	meiotic DNA integrity checkpoint	https://github.com/geneontology/go-ontology/issues/20935					jl	2013-03-20T16:46:06Z						biological_process											owl:Class	
GO:0103045	biolink:NamedThing	methione N-acyltransferase activity	Catalysis of the reaction: L-methionine  + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+.	got7fsn_ti												RHEA:44144|EC:2.3.1.1|MetaCyc:RXN0-6948		molecular_function											owl:Class	
GO:0050181	biolink:NamedThing	phorbol-diester hydrolase activity	Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate.	got7fsn_ti	diacylphorbate 12-hydrolase activity|phorbol-12,13-diester 12-ester hydrolase activity|PDEH|12,13-diacylphorbate 12-acylhydrolase activity											KEGG_REACTION:R04119|RHEA:21316|MetaCyc:PHORBOL-DIESTER-HYDROLASE-RXN|EC:3.1.1.51		molecular_function											owl:Class	
GO:1905368	biolink:NamedThing	peptidase complex	A protein complex which is capable of peptidase activity.	got7fsn_ti	tryptase complex|protease complex				An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay).		bhm	2016-08-16T12:49:36Z						cellular_component											owl:Class	
GO:0036428	biolink:NamedThing	adenosylcobinamide kinase (GTP-specific) activity	Catalysis of the reaction: adenosylcobinamide + GTP = adenosylcobinamide phosphate + GDP + H+.	got7fsn_ti							bf	2013-09-16T14:05:39Z				RHEA:15765|KEGG_REACTION:R06558|MetaCyc:RXN-14063		molecular_function											owl:Class	
GO:1990601	biolink:NamedThing	5' overhang single-stranded DNA endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks.	got7fsn_ti							al	2015-01-06T16:24:39Z						molecular_function											owl:Class	
GO:2001030	biolink:NamedThing	negative regulation of cellular glucuronidation	Any process that stops, prevents or reduces the frequency, rate or extent of cellular glucuronidation.	got7fsn_ti	negative regulation of cellular glucuronoside biosynthesis|negative regulation of cellular glucuronide biosynthetic process|negative regulation of cellular glucuronoside biosynthetic process|negative regulation of cellular glucuronide biosynthesis						rl	2011-08-22T01:10:56Z						biological_process											owl:Class	
GO:0033997	biolink:NamedThing	inulin fructotransferase (DFA-I-forming) activity	Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.	got7fsn_ti	2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,1'-dianhydride-forming) activity|inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':1',2-dianhydride) activity|inulin fructotransferase (DFA-I-producing) activity|inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-forming) activity|inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming) activity											EC:4.2.2.17|MetaCyc:4.2.2.17-RXN		molecular_function											owl:Class	
GO:0018270	biolink:NamedThing	GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	got7fsn_ti	GPI anchor synthesis via N-alanyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-alanyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-alanyl-glycosylphosphatidylinositolethanolamine											RESID:AA0163		biological_process											owl:Class	
GO:0036412	biolink:NamedThing	acetyl-CoA:oxalate CoA-transferase	Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.	got7fsn_ti							bf	2013-08-22T13:43:25Z				RHEA:37883		molecular_function											owl:Class	
GO:1903503	biolink:NamedThing	ATPase inhibitor complex	A protein complex which is capable of ATPase inhibitor activity.	got7fsn_ti					An example of this is Mago in drome (P49028) in PMID:16170325 (inferred from direct assay).		bhm	2014-09-30T13:55:37Z						cellular_component											owl:Class	
GO:0072219	biolink:NamedThing	metanephric cortical collecting duct development	The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.	got7fsn_ti							mah	2010-03-18T03:34:52Z						biological_process											owl:Class	
GO:0018796	biolink:NamedThing	4,5-dihydroxyphthalate decarboxylase activity	Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.	got7fsn_ti	4,5-dihydroxyphthalate carboxy-lyase activity|4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)											MetaCyc:45-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN|UM-BBD_enzymeID:e0106|EC:4.1.1.55|RHEA:24184		molecular_function											owl:Class	
GO:0047072	biolink:NamedThing	2,3-dihydroxybenzoate 2,3-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-carboxy-cis,cis-muconate + 2 H(+).	got7fsn_ti	2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing)|2,3-dihydroxybenzoate 2,3-oxygenase activity											RHEA:15369|MetaCyc:1.13.11.28-RXN|KEGG_REACTION:R01506|EC:1.13.11.28		molecular_function											owl:Class	
GO:0043738	biolink:NamedThing	reduced coenzyme F420 dehydrogenase activity	Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420.	got7fsn_ti	F420H2 dehydrogenase activity|1,5-dihydrocoenzyme F420 dehydrogenase activity											MetaCyc:RXN-8106|EC:1.5.98.3|RHEA:54752		molecular_function											owl:Class	
NCBITaxon:1	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBI:0100026	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009550	biolink:NamedThing	primary plasmodesma	A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis.	got7fsn_ti	simple plasmodesma													cellular_component											owl:Class	
GO:0031891	biolink:NamedThing	type 1 vasoactive intestinal polypeptide receptor binding	Binding to a type 1 vasoactive intestinal polypeptide receptor.	got7fsn_ti	type 2 PACAP receptor binding|type 1 vasoactive intestinal polypeptide receptor ligand													molecular_function											owl:Class	
GO:0031686	biolink:NamedThing	A1 adenosine receptor binding	Binding to an A1 adenosine receptor.	got7fsn_ti	A1 adenosine receptor ligand													molecular_function											owl:Class	
GO:0043873	biolink:NamedThing	pyruvate-flavodoxin oxidoreductase activity	Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.	got7fsn_ti	pyruvate:flavodoxin oxidoreductase activity|NifJ											MetaCyc:PYFLAVOXRE-RXN|RHEA:44140		molecular_function											owl:Class	
GO:0018456	biolink:NamedThing	aryl-alcohol dehydrogenase (NAD+) activity	Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+.	got7fsn_ti	p-hydroxybenzyl alcohol dehydrogenase activity|aryl-alcohol:NAD+ oxidoreductase activity|benzyl alcohol dehydrogenase activity											UM-BBD_enzymeID:e0019|MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-RXN|EC:1.1.1.90|RHEA:12076		molecular_function											owl:Class	
GO:0098002	biolink:NamedThing	receptor-mediated bacteriophage irreversible attachment to host cell	The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell.	got7fsn_ti	phage irreversible adsorption|irreversible bacteriophage attachment, binding of host cell surface receptor						bm							biological_process											owl:Class	
GO:0030946	biolink:NamedThing	protein tyrosine phosphatase activity, metal-dependent	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions.	got7fsn_ti														molecular_function											owl:Class	
GO:0102627	biolink:NamedThing	parthenolide 3beta-hydroxylase activity	Catalysis of the reaction: parthenolide + NADPH + O2 + H+ <=> 3beta-hydroxyparthenolide + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-15532		molecular_function											owl:Class	
GO:0047729	biolink:NamedThing	carnitine decarboxylase activity	Catalysis of the reaction: carnitine + H(+) = 2-methylcholine + CO(2).	got7fsn_ti	carnitine carboxy-lyase (2-methylcholine-forming)|carnitine carboxy-lyase activity											KEGG_REACTION:R02398|MetaCyc:CARNITINE-DECARBOXYLASE-RXN|RHEA:21576|EC:4.1.1.42		molecular_function											owl:Class	
GO:0033433	biolink:NamedThing	AUU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AUU codon.	got7fsn_ti	isoleucine tRNA|ATT codon-amino acid adaptor activity				Note that in the standard genetic code, ATT codes for isoleucine.									molecular_function											owl:Class	
GO:0046486	biolink:NamedThing	glycerolipid metabolic process	The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.	got7fsn_ti	glycerolipid metabolism													biological_process											owl:Class	
GO:0008404	biolink:NamedThing	arachidonic acid 14,15-epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid.	got7fsn_ti	cytochrome P450 CYP2C39|cytochrome P450 CYP2C29											RHEA:51472		molecular_function											owl:Class	
GO:0003952	biolink:NamedThing	NAD+ synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.	got7fsn_ti	NAD synthetase (glutamine-hydrolysing)|desamidonicotinamide adenine dinucleotide amidotransferase activity|NAD synthase (glutamine-hydrolyzing) activity|NAD(+) synthetase (glutamine-hydrolyzing) activity|nicotinamide adenine dinucleotide synthetase (glutamine) activity|DPN synthetase activity|NAD+ synthase (glutamine-hydrolysing)|deamido-NAD+:L-glutamine amido-ligase (AMP-forming)|NAD+ synthetase (glutamine-hydrolyzing)											Wikipedia:NAD+_synthase_(glutamine-hydrolysing)|EC:6.3.5.1|RHEA:24384|MetaCyc:NAD-SYNTH-GLN-RXN|Reactome:R-HSA-197271		molecular_function											owl:Class	
GO:0043737	biolink:NamedThing	deoxyribonuclease V activity	Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.	got7fsn_ti	DNase V activity|endodeoxyribonuclease V|Escherichia coli endodeoxyribonuclease V activity|endonuclease V activity											MetaCyc:3.1.21.7-RXN|EC:3.1.21.7		molecular_function											owl:Class	
GO:0006664	biolink:NamedThing	glycolipid metabolic process	The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.	got7fsn_ti	glycolipid metabolism													biological_process											owl:Class	
GO:0008794	biolink:NamedThing	arsenate reductase (glutaredoxin) activity	Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.	got7fsn_ti	glutharedoxin:arsenate oxidoreductase activity											RHEA:22016|UM-BBD_reactionID:r0635|MetaCyc:RXN-982|EC:1.20.4.1		molecular_function											owl:Class	
GO:0018340	biolink:NamedThing	peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine	The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine.	got7fsn_ti	peptidyl-O-(sn-1-glycerophosphoryl)-L-serine anabolism from peptidyl-serine|peptidyl-O-(sn-1-glycerophosphoryl)-L-serine synthesis from peptidyl-serine|peptidyl-O-(sn-1-glycerophosphoryl)-L-serine formation from peptidyl-serine											RESID:AA0264		biological_process											owl:Class	
GO:0031698	biolink:NamedThing	beta-2 adrenergic receptor binding	Binding to a beta-2 adrenergic receptor.	got7fsn_ti	beta-2 adrenergic receptor ligand													molecular_function											owl:Class	
GO:0018404	biolink:NamedThing	protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.	got7fsn_ti	protein-heparan sulphate linkage via heparan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine											RESID:AA0210		biological_process											owl:Class	
GO:0008405	biolink:NamedThing	arachidonic acid 11,12-epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid.	got7fsn_ti	cytochrome P450 CYP2C38											RHEA:51480		molecular_function											owl:Class	
GO:0097127	biolink:NamedThing	cyclin B3-CDK2 complex	A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti							pr	2011-08-01T01:47:16Z						cellular_component											owl:Class	
GO:0018490	biolink:NamedThing	4-hydroxyphenylpyruvate oxidase activity	Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2).	got7fsn_ti	4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)											KEGG_REACTION:R00042|RHEA:17197|EC:1.2.3.13|UM-BBD_reactionID:r0299|MetaCyc:1.2.3.13-RXN		molecular_function											owl:Class	
GO:0102900	biolink:NamedThing	dehydroabietadienal hydroxylase activity	Catalysis of the reaction: dehydroabietadienal + NADPH + O2 <=> dehydroabietic acid + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-8534		molecular_function											owl:Class	
GO:0047058	biolink:NamedThing	vitamin-K-epoxide reductase (warfarin-insensitive) activity	Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol.	got7fsn_ti	vitamin K 2,3-epoxide reductase activity	https://github.com/geneontology/go-ontology/issues/21412			Formerly EC:1.1.4.2.							MetaCyc:1.1.4.2-RXN|EC:1.17.4.5|RHEA:21560		molecular_function											owl:Class	
GO:0006437	biolink:NamedThing	tyrosyl-tRNA aminoacylation	The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0047360	biolink:NamedThing	undecaprenyl-phosphate galactose phosphotransferase activity	Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP.	got7fsn_ti	undecaprenyl phosphate galactosyl-1-phosphate transferase activity|poly(isoprenyl)phosphate galactosephosphatetransferase activity|poly(isoprenol)-phosphate galactose phosphotransferase activity|UDP-galactose:undecaprenyl-phosphate galactose phosphotransferase activity|poly(isoprenol)-phosphate galactosephosphotransferase activity											RHEA:11652|KEGG_REACTION:R01535|EC:2.7.8.6|MetaCyc:2.7.8.6-RXN		molecular_function											owl:Class	
GO:0102481	biolink:NamedThing	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity	Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H+.	got7fsn_ti												MetaCyc:RXN-14149|EC:3.7.1.22|RHEA:25836		molecular_function											owl:Class	
GO:0102493	biolink:NamedThing	wogonin 7-O-glucosyltransferase activity	Catalysis of the reaction: wogonin + UDP-alpha-D-glucose <=> wogonin 7-O-beta-D-glucoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-14239		molecular_function											owl:Class	
GO:0010288	biolink:NamedThing	response to lead ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0005168	biolink:NamedThing	neurotrophin TRKA receptor binding	Binding to a neurotrophin TRKA receptor.	got7fsn_ti	neurotrophin TRKA receptor ligand													molecular_function											owl:Class	
GO:0070710	biolink:NamedThing	RNA uridine deletion	The modification of an RNA molecule by removal of a uridine nucleotide.	got7fsn_ti	RNA U deletion|RNA uridine excision						mah	2009-06-08T05:12:43Z						biological_process											owl:Class	
GO:0005607	biolink:NamedThing	laminin-2 complex	A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.	got7fsn_ti	laminin-211 complex													cellular_component											owl:Class	
GO:0006539	biolink:NamedThing	glutamate catabolic process via 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.	got7fsn_ti	glutamate catabolic process via alpha-ketoglutarate|glutamate catabolic process via alpha-oxoglutarate|glutamate catabolism via alpha-ketoglutarate|glutamate breakdown via 2-oxoglutarate|glutamate degradation via 2-oxoglutarate|glutamate catabolic process via 2-ketoglutarate|glutamate catabolism via alpha-oxoglutarate|glutamate catabolism via 2-ketoglutarate											MetaCyc:P162-PWY		biological_process											owl:Class	
GO:0002753	biolink:NamedThing	cytoplasmic pattern recognition receptor signaling pathway	Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.	got7fsn_ti	cytoplasmic PAMP receptor signaling pathway|cytoplasmic pathogen receptor signaling pathway|cytoplasmic PRR signaling pathway|cytoplasmic pattern recognition receptor signalling pathway	https://github.com/geneontology/go-ontology/issues/18588												biological_process											owl:Class	
GO:0050928	biolink:NamedThing	negative regulation of positive chemotaxis	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	got7fsn_ti	inhibition of positive chemotaxis|down-regulation of positive chemotaxis|down regulation of positive chemotaxis|downregulation of positive chemotaxis													biological_process											owl:Class	
GO:0034927	biolink:NamedThing	pyrene 1,2-monooxygenase activity	Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O.	got7fsn_ti												UM-BBD_reactionID:r0943		molecular_function											owl:Class	
GO:0006104	biolink:NamedThing	succinyl-CoA metabolic process	The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.	got7fsn_ti	succinyl-CoA metabolism													biological_process											owl:Class	
GO:0030737	biolink:NamedThing	iodophenol O-methyltransferase activity	Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	S-adenosyl-L-methionine:2-iodophenol O-methyltransferase activity											MetaCyc:IODOPHENOL-O-METHYLTRANSFERASE-RXN|EC:2.1.1.26|RHEA:14313|KEGG_REACTION:R03746		molecular_function											owl:Class	
GO:0050303	biolink:NamedThing	lysine 6-dehydrogenase activity	Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine.	got7fsn_ti	L-lysine epsilon-dehydrogenase activity|L-lysine:NAD+ 6-oxidoreductase (deaminating)|L-lysine 6-dehydrogenase activity|LysDH activity											MetaCyc:LYSINE-6-DEHYDROGENASE-RXN|RHEA:12408|EC:1.4.1.18|MetaCyc:PWY-5314		molecular_function											owl:Class	
GO:0019710	biolink:NamedThing	peptidyl-asparagine methylation	The methylation of peptidyl-asparagine to form peptidyl-N4-methyl-L-asparagine or peptidyl-N4,N4-dimethyl-L-asparagine.	got7fsn_ti											GO:0018018	RESID:AA0311|RESID:AA0070		biological_process											owl:Class	
GO:0102062	biolink:NamedThing	alpha-santalene synthase activity	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-alpha-santalene + diphosphoric acid.	got7fsn_ti												RHEA:30463|EC:4.2.3.50|MetaCyc:RXN-10567		molecular_function											owl:Class	
GO:0047049	biolink:NamedThing	(R)-2-hydroxy-fatty acid dehydrogenase activity	Catalysis of the reaction: (R)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH.	got7fsn_ti	2-hydroxy fatty acid oxidase|(R)-2-hydroxy-fatty-acid dehydrogenase activity|(R)-2-hydroxystearate:NAD+ oxidoreductase activity|D-2-hydroxy fatty acid dehydrogenase activity											MetaCyc:1.1.1.98-RXN|RHEA:15949|EC:1.1.1.98|KEGG_REACTION:R03021		molecular_function											owl:Class	
GO:1900765	biolink:NamedThing	emericellin catabolic process	The chemical reactions and pathways resulting in the breakdown of emericellin.	got7fsn_ti	Variecoxanthone B catabolism|emericellin breakdown|Variecoxanthone B breakdown|emericellin degradation|Variecoxanthone B degradation|emericellin catabolism|Variecoxanthone B catabolic process						di	2012-06-04T09:18:22Z						biological_process											owl:Class	
GO:0008312	biolink:NamedThing	7S RNA binding	Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).	got7fsn_ti														molecular_function											owl:Class	
GO:0102043	biolink:NamedThing	isopentenyl phosphate kinase activity	Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) <=> isopentenyl diphosphate(3-) + ADP(3-).	got7fsn_ti												MetaCyc:RXN-10068|EC:2.7.4.26|RHEA:33963		molecular_function											owl:Class	
GO:0047418	biolink:NamedThing	phthalyl amidase activity	Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine.	got7fsn_ti	phthalyl-amide amidohydrolase activity|o-phthalyl amidase activity											EC:3.5.1.79|MetaCyc:3.5.1.79-RXN|RHEA:18297		molecular_function											owl:Class	
GO:0070635	biolink:NamedThing	nicotinamide riboside hydrolase activity	Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.	got7fsn_ti	N-ribosylnicotinamide hydrolase activity|nicotinamide ribonucleoside hydrolase activity						mah	2009-05-07T02:01:42Z				MetaCyc:RXN-8441		molecular_function											owl:Class	
GO:0060101	biolink:NamedThing	negative regulation of phagocytosis, engulfment	Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0050765	biolink:NamedThing	negative regulation of phagocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.	got7fsn_ti	inhibition of phagocytosis|down-regulation of phagocytosis|down regulation of phagocytosis|downregulation of phagocytosis													biological_process											owl:Class	
GO:0061217	biolink:NamedThing	regulation of mesonephros development	Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti							dph	2010-08-17T03:35:31Z						biological_process											owl:Class	
GO:1990841	biolink:NamedThing	promoter-specific chromatin binding	Binding to a section of chromatin that is associated with gene promoter sequences of DNA.	got7fsn_ti							sl	2015-08-28T14:48:29Z						molecular_function											owl:Class	
GO:0050254	biolink:NamedThing	rhodopsin kinase activity	Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin.	got7fsn_ti	GRK1|cone opsin kinase activity|ATP:rhodopsin phosphotransferase activity|rhodopsin kinase (phosphorylating) activity|G-protein-coupled receptor kinase 1 activity|GPCR kinase 1 activity|GRK7|opsin kinase activity|STK14|opsin kinase (phosphorylating) activity|RK											MetaCyc:2.7.11.14-RXN|EC:2.7.11.14|RHEA:23356|Reactome:R-HSA-2581474		molecular_function											owl:Class	
GO:1900608	biolink:NamedThing	tensidol B biosynthetic process	The chemical reactions and pathways resulting in the formation of tensidol B.	got7fsn_ti	tensidol B synthesis|tensidol B biosynthesis|tensidol B formation|tensidol B anabolism						di	2012-05-15T06:58:51Z						biological_process											owl:Class	
GO:0004590	biolink:NamedThing	orotidine-5'-phosphate decarboxylase activity	Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.	got7fsn_ti	UMP synthase activity|OMP-DC|orotidylic decarboxylase activity|ODCase activity|orotodylate decarboxylase activity|orotate monophosphate decarboxylase activity|orotidine-5'-monophosphate decarboxylase activity|orotidine-5'-phosphate carboxy-lyase (UMP-forming)|orotic decarboxylase activity|orotidine-5'-phosphate carboxy-lyase activity|OMP decarboxylase activity|OMPdcase activity|uridine 5'-monophosphate synthase activity|orotidine monophosphate decarboxylase activity|orotidine phosphate decarboxylase activity|orotidine 5'-phosphate decarboxylase activity|orotidylic acid decarboxylase activity|orotate decarboxylase activity											EC:4.1.1.23|MetaCyc:OROTPDECARB-RXN|Reactome:R-HSA-73564|KEGG_REACTION:R00965|RHEA:11596		molecular_function											owl:Class	
GO:0036514	biolink:NamedThing	dopaminergic neuron axon guidance	The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.	got7fsn_ti	mdDA axon guidance|DA axon guidance|dopaminergic axon guidance						bf	2015-12-17T11:14:20Z						biological_process											owl:Class	
GO:0098669	biolink:NamedThing	superinfection exclusion	The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus.  Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented.	got7fsn_ti							dos	2017-01-16T17:25:21Z				VZ:3971		biological_process											owl:Class	
GO:0046988	biolink:NamedThing	asioloorosomucoid beta-1,3-glucuronosyltransferase activity	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.	got7fsn_ti														molecular_function											owl:Class	
GO:0052822	biolink:NamedThing	DNA-3-methylguanine glycosylase activity	Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site.	got7fsn_ti	alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|3-methylguanine DNA glycosylase I|deoxyribonucleate 3-methylguanine glycosidase I|DNA glycosidase I activity						ai	2011-10-28T02:28:19Z				MetaCyc:3.2.2.21-RXN|EC:3.2.2.21		molecular_function											owl:Class	
GO:0010267	biolink:NamedThing	production of ta-siRNAs involved in RNA interference	Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs.	got7fsn_ti	RNA interference, production of ta-siRNAs													biological_process											owl:Class	
GO:0047034	biolink:NamedThing	15-hydroxyicosatetraenoate dehydrogenase activity	Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.	got7fsn_ti	15-hydroxyeicosatetraenoate dehydrogenase activity|(15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase activity											MetaCyc:1.1.1.232-RXN|EC:1.1.1.232|Reactome:R-HSA-2161789		molecular_function											owl:Class	
GO:0062139	biolink:NamedThing	camera-type eye photoreceptor cell development	The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure.	got7fsn_ti							dph	2019-08-06T12:40:36Z						biological_process											owl:Class	
GO:0060081	biolink:NamedThing	membrane hyperpolarization	The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.	got7fsn_ti														biological_process											owl:Class	
GO:0034921	biolink:NamedThing	cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity	Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r0935		molecular_function											owl:Class	
GO:0070218	biolink:NamedThing	sulfide ion homeostasis	Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell.	got7fsn_ti	sulphide ion homeostasis|sulphide generation|sulfide homeostasis|sulfide generation|sulphide homeostasis|sulfide production|sulphide production													biological_process											owl:Class	
GO:0050229	biolink:NamedThing	pterocarpin synthase activity	Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH.	got7fsn_ti	medicarpin:NADP+ 2'-oxidoreductase activity|pterocarpan synthase activity											EC:1.1.1.246|MetaCyc:PTEROCARPIN-SYNTHASE-RXN|RHEA:13533		molecular_function											owl:Class	
GO:0050439	biolink:NamedThing	2-hydroxy-3-oxoadipate synthase activity	Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO(2).	got7fsn_ti	oxoglutarate:glyoxylate carboligase activity|alpha-ketoglutaric-glyoxylic carboligase activity|oxoglutarate: glyoxylate carboligase activity|2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating) activity|2-hydroxy-3-oxoadipate synthetase activity|2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating)											RHEA:14341|EC:2.2.1.5|KEGG_REACTION:R00474|MetaCyc:2-HYDROXY-3-OXOADIPATE-SYNTHASE-RXN		molecular_function											owl:Class	
GO:0072631	biolink:NamedThing	interleukin-29 production	The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IL29 production|IL-29 production|interferon lambda 1 production|interleukin-29 secretion				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072632			biological_process											owl:Class	
GO:0034874	biolink:NamedThing	thioacetamide S-oxide S-oxygenase activity	Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.	got7fsn_ti												UM-BBD_reactionID:r1313		molecular_function											owl:Class	
GO:0061734	biolink:NamedThing	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.	got7fsn_ti	Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization						dph	2015-09-14T13:48:57Z						biological_process											owl:Class	
GO:0008226	biolink:NamedThing	tyramine receptor activity	Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.	got7fsn_ti														molecular_function											owl:Class	
GO:0099070	biolink:NamedThing	static microtubule bundle	A microtubule bundle that has a constant length, and in which microtubule sliding does not take place.	got7fsn_ti	quiescent cell microtubule bundle|quiescent cell MT bundle|Q-MT bundle				In fission yeast, quiescent cells contain only static microtubule bundles.									cellular_component											owl:Class	
GO:0010715	biolink:NamedThing	regulation of extracellular matrix disassembly	Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.	got7fsn_ti	regulation of extracellular matrix breakdown|regulation of extracellular matrix degradation													biological_process											owl:Class	
GO:1990155	biolink:NamedThing	Dsc E3 ubiquitin ligase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane.	got7fsn_ti	Dsc complex assembly						mah	2013-08-01T14:19:19Z						biological_process											owl:Class	
GO:0032444	biolink:NamedThing	activin responsive factor complex	A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.	got7fsn_ti	ARF complex				Note that this term should not be confused with any of the molecular function and biological process terms that refer to the small GTPase ARF (ADP-ribosylation factor).									cellular_component											owl:Class	
GO:0106105	biolink:NamedThing	Ala-tRNA(Thr) hydrolase activity	Catalysis of the hydrolysis of misacylated ala-tRNA(thr).	got7fsn_ti	L-alanyl-tRNA(Thr) deacylase						hjd	2018-03-14T22:03:29Z						molecular_function											owl:Class	
GO:0019158	biolink:NamedThing	mannokinase activity	Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate.	got7fsn_ti	D-fructose (D-mannose) kinase activity|ATP:D-mannose 6-phosphotransferase activity|mannokinase (phosphorylating)											MetaCyc:MANNKIN-RXN|RHEA:11028|EC:2.7.1.7		molecular_function											owl:Class	
GO:0050419	biolink:NamedThing	hydroxymandelonitrile lyase activity	Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate.	got7fsn_ti	(S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase activity|(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)|hydroxynitrile lyase activity|sorghum hydroxynitrile lyase activity											EC:4.1.2.11|MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN|RHEA:15977		molecular_function											owl:Class	
GO:0007580	biolink:NamedThing	extrachromosomal circular DNA accumulation involved in cell aging	Increase in abundance, as cells age, of circular DNA molecules that originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and replicated independently of chromosomal replication.	got7fsn_ti	extrachromosomal circular DNA accumulation during cell ageing|extrachromosomal circular DNA accumulation during cell aging				Note that the term string was changed to be consistent with placement of this term in cell aging hierarchy.									biological_process											owl:Class	
GO:0018628	biolink:NamedThing	terephthalate 1,2-dioxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+).	got7fsn_ti	benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)|1,4-dicarboxybenzoate 1,2-dioxygenase activity|benzene-1,4-dicarboxylate 1,2-dioxygenase activity											RHEA:10312|MetaCyc:1.14.12.15-RXN|UM-BBD_reactionID:r0150|KEGG_REACTION:R05148|EC:1.14.12.15		molecular_function											owl:Class	
GO:0036517	biolink:NamedThing	chemoattraction of serotonergic neuron axon	The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.	got7fsn_ti	chemoattraction of serotonergic axon|chemoattraction of 5-HT axon						bf	2015-12-17T11:26:03Z						biological_process											owl:Class	
GO:0004668	biolink:NamedThing	protein-arginine deiminase activity	Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3. This reaction is calcium-dependent.	got7fsn_ti	protein-L-arginine iminohydrolase activity|peptidylarginine deiminase activity	https://github.com/geneontology/go-ontology/issues/18666										Reactome:R-HSA-3247569|EC:3.5.3.15|MetaCyc:PROTEIN-ARGININE-DEIMINASE-RXN|RHEA:18089|Reactome:R-HSA-1183128		molecular_function											owl:Class	
GO:0035733	biolink:NamedThing	hepatic stellate cell activation	A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.	got7fsn_ti							bf	2011-03-11T10:04:12Z						biological_process											owl:Class	
GO:0050490	biolink:NamedThing	1,4-lactonase activity	Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid.	got7fsn_ti	1,4-lactone hydroxyacylhydrolase activity|gamma-lactonase activity											MetaCyc:14-LACTONASE-RXN|EC:3.1.1.25|RHEA:12745		molecular_function											owl:Class	
GO:0002273	biolink:NamedThing	plasmacytoid dendritic cell differentiation	The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell.	got7fsn_ti														biological_process											owl:Class	
GO:0035750	biolink:NamedThing	protein localization to myelin sheath abaxonal region	Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.	got7fsn_ti	protein localisation to myelin sheath abaxonal region						bf	2011-03-23T10:20:06Z						biological_process											owl:Class	
GO:0002358	biolink:NamedThing	B cell homeostatic proliferation	The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.	got7fsn_ti	B-lymphocyte homeostatic proliferation|B-cell homeostatic proliferation|B lymphocyte homeostatic proliferation													biological_process											owl:Class	
GO:0044393	biolink:NamedThing	microspike	A dynamic, actin-rich projection extending from the surface of a migrating animal cell.	got7fsn_ti					Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. See also 'filopodium ; GO:0030175'.		bf	2011-12-06T01:31:16Z						cellular_component											owl:Class	
GO:0070411	biolink:NamedThing	I-SMAD binding	Binding to an inhibitory SMAD signaling protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0035341	biolink:NamedThing	regulation of inosine transport	Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of hypoxanthine riboside transport						bf	2010-03-04T10:03:51Z						biological_process											owl:Class	
GO:0003271	biolink:NamedThing	smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	hh signaling pathway involved in regulation of second heart field cardioblast proliferation|smoothened receptor signalling pathway involved in regulation of secondary heart field cardioblast proliferation|smoothened receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation|smoothened receptor signaling pathway involved in regulation of second heart field cardioblast proliferation|hedgehog signaling pathway involved in regulation of second heart field cardioblast proliferation						dph	2009-10-15T02:48:32Z						biological_process											owl:Class	
GO:0061311	biolink:NamedThing	cell surface receptor signaling pathway involved in heart development	Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time.	got7fsn_ti	cell surface receptor linked signalling pathway involved in heart development|cell surface receptor linked signaling pathway involved in heart development						dph	2010-09-23T09:18:32Z						biological_process											owl:Class	
GO:0031419	biolink:NamedThing	cobalamin binding	Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	got7fsn_ti	vitamin B12 binding													molecular_function											owl:Class	
GO:1990532	biolink:NamedThing	stress response to nickel ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus.	got7fsn_ti	stress response to nickel|response to nickel ion stress|response to nickel toxicity						kmv	2014-11-07T18:35:31Z						biological_process											owl:Class	
GO:0002153	biolink:NamedThing	steroid receptor RNA activator RNA binding	Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.	got7fsn_ti	SRA binding				Note: there is also evidence that the RNA itself may code a protein (solution structure of mouse steroid receptor RNA activator 1 (SRA1) protein submitted to PDB by Riken).		hjd	2009-11-16T02:18:55Z						molecular_function											owl:Class	
GO:0016807	biolink:NamedThing	cysteine-type carboxypeptidase activity	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19681										EC:3.4.18.-|MetaCyc:3.4.18.1-RXN		molecular_function											owl:Class	
GO:0034016	biolink:NamedThing	polyenoic fatty acid isomerase activity	Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate.	got7fsn_ti	(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity|(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity|(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,8-isomerase activity|PFI|eicosapentaenoate cis-delta5,8,11,14,17-eicosapentaenoate cis-delta5-trans-delta7,9-cis-delta14,17 isomerase activity											KEGG_REACTION:R06502|MetaCyc:5.3.3.13-RXN|RHEA:14889|EC:5.3.3.13		molecular_function											owl:Class	
GO:0098632	biolink:NamedThing	cell-cell adhesion mediator activity	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.	got7fsn_ti	cell-cell adhesion molecule|protein binding involved in cell-cell adhesion													molecular_function											owl:Class	
GO:0048689	biolink:NamedThing	formation of growth cone in injured axon	The formation of a growth cone in an injured axon.	got7fsn_ti														biological_process											owl:Class	
GO:0018618	biolink:NamedThing	anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity	Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3.	got7fsn_ti	anthranilate dioxygenase activity|anthranilic acid hydroxylase activity|AntA|anthranilic hydroxylase activity|AntC|anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)|AntB|anthranilate 1,2-dioxygenase|anthranilate hydroxylase activity|anthranilate dioxygenase reductase											MetaCyc:1.14.12.1-RXN|UM-BBD_reactionID:r0577|EC:1.14.12.1		molecular_function											owl:Class	
GO:0031071	biolink:NamedThing	cysteine desulfurase activity	Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.	got7fsn_ti	SufS|NIFS|cysteine desulfurylase activity|L-cysteine:enzyme cysteine sulfurtransferase activity|IscS											Reactome:R-HSA-947514|EC:2.8.1.7|RHEA:43892|Reactome:R-HSA-1362408		molecular_function											owl:Class	
GO:0050288	biolink:NamedThing	sorbose dehydrogenase activity	Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2).	got7fsn_ti	L-sorbose:(acceptor) 5-oxidoreductase activity|L-sorbose:acceptor 5-oxidoreductase activity											EC:1.1.99.12|RHEA:14713|MetaCyc:SORBOSE-DEHYDROGENASE-RXN|KEGG_REACTION:R01696		molecular_function											owl:Class	
GO:0018820	biolink:NamedThing	cyanamide hydratase activity	Catalysis of the reaction: urea = cyanamide + H(2)O.	got7fsn_ti	urea hydro-lyase (cyanamide-forming)|urea hydro-lyase activity											MetaCyc:CYANAMIDE-HYDRATASE-RXN|EC:4.2.1.69|UM-BBD_reactionID:r0668|KEGG_REACTION:R00778|RHEA:23056		molecular_function											owl:Class	
GO:0008959	biolink:NamedThing	phosphate acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate.	got7fsn_ti	phosphoacylase activity|PTA|phosphotransacetylase activity|acetyl-CoA:phosphate acetyltransferase activity											RHEA:19521|EC:2.3.1.8|MetaCyc:PHOSACETYLTRANS-RXN		molecular_function											owl:Class	
GO:0004945	biolink:NamedThing	angiotensin type II receptor activity	An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms.	got7fsn_ti														molecular_function											owl:Class	
GO:0019755	biolink:NamedThing	one-carbon compound transport	The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	one carbon compound transport													biological_process											owl:Class	
GO:0005683	biolink:NamedThing	U7 snRNP	A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs.	got7fsn_ti	snRNP U7													cellular_component											owl:Class	
GO:0043184	biolink:NamedThing	vascular endothelial growth factor receptor 2 binding	Binding to a vascular endothelial growth factor receptor 2.	got7fsn_ti	VEGF receptor 2 binding|VEGFR 2 binding|KDR binding|kinase domain region binding|Flk-1 binding													molecular_function											owl:Class	
GO:0044299	biolink:NamedThing	C-fiber	The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated.	got7fsn_ti	C-fibre						jl	2010-02-05T11:14:51Z				NIF_Subcellular:nlx_subcell_20090210		cellular_component											owl:Class	
GO:0098914	biolink:NamedThing	membrane repolarization during atrial cardiac muscle cell action potential	The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	got7fsn_ti	electrocardiogram QRS complex|atrial repolarization													biological_process											owl:Class	
GO:0030797	biolink:NamedThing	24-methylenesterol C-methyltransferase activity	Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+).	got7fsn_ti	24-methylenelophenol C-241-methyltransferase activity|24-methylenelophenol C-24(1)-methyltransferase activity|SMT2|S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase activity|SMT(2) activity											RHEA:21044|KEGG_REACTION:R05776|EC:2.1.1.143|MetaCyc:2.1.1.143-RXN		molecular_function											owl:Class	
GO:0070766	biolink:NamedThing	endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex	A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof).	got7fsn_ti	Stx4-Napa-Vamp3-Nsf-Vamp2 complex|SNARE complex (Stx4, Napa, Vamp3, Nsf, Vamp2)						mah	2009-06-29T04:41:55Z						cellular_component											owl:Class	
GO:0036082	biolink:NamedThing	extracellular phenylacetaldehyde-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	ionotropic phenylacetaldehyde receptor activity						bf	2011-12-20T04:49:31Z						molecular_function											owl:Class	
GO:0043705	biolink:NamedThing	cyanophycin metabolic process	The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups.	got7fsn_ti	cyanophycin metabolism|multi-L-arginyl-poly(L-aspartic acid) metabolism													biological_process											owl:Class	
GO:0035342	biolink:NamedThing	positive regulation of inosine transport	Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	positive regulation of hypoxanthine riboside transport						bf	2010-03-04T10:05:03Z						biological_process											owl:Class	
GO:0050232	biolink:NamedThing	putrescine oxidase activity	Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2.	got7fsn_ti	putrescine:oxygen oxidoreductase (deaminating)											EC:1.4.3.10|MetaCyc:PUTRESCINE-OXIDASE-RXN|RHEA:18273		molecular_function											owl:Class	
GO:0009386	biolink:NamedThing	translational attenuation	Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation.	got7fsn_ti														biological_process											owl:Class	
GO:0047454	biolink:NamedThing	phaseollidin hydratase activity	Catalysis of the reaction: phaseollidin hydrate = H(2)O + phaseollidin.	got7fsn_ti	phaseollidin-hydrate hydro-lyase activity|phaseollidin-hydrate hydro-lyase (phaseollidin-forming)											KEGG_REACTION:R04728|MetaCyc:4.2.1.97-RXN|RHEA:19769|EC:4.2.1.97		molecular_function											owl:Class	
GO:1902159	biolink:NamedThing	regulation of cyclic nucleotide-gated ion channel activity	Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.	got7fsn_ti	regulation of cyclic nucleotide-activated ion channel activity|regulation of cyclic nucleotide gated ion channel activity|regulation of cyclic nucleotide activated ion channel activity						sl	2013-05-21T19:24:30Z						biological_process											owl:Class	
GO:0050249	biolink:NamedThing	Renilla-luciferin sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H(+) + luciferyl sulfate.	got7fsn_ti	luciferin sulfotransferase activity|luciferin sulfokinase activity|Renilla-luciferin sulphotransferase activity|luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase)|3'-phosphoadenylyl-sulfate:Renilla luciferin sulfotransferase activity											EC:2.8.2.10|RHEA:20481|MetaCyc:RENILLA-LUCIFERIN-SULFOTRANSFERASE-RXN|KEGG_REACTION:R03138		molecular_function											owl:Class	
GO:0047675	biolink:NamedThing	arabinonate dehydratase activity	Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O.	got7fsn_ti	D-arabinonate hydro-lyase activity|D-arabinonate hydro-lyase (2-dehydro-3-deoxy-D-arabinonate-forming)											EC:4.2.1.5|MetaCyc:ARABINONATE-DEHYDRATASE-RXN|RHEA:21836|KEGG_REACTION:R03032		molecular_function											owl:Class	
GO:0106306	biolink:NamedThing	protein serine phosphatase activity	Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate.	got7fsn_ti							hjd	2020-09-09T19:36:32Z				EC:3.1.3.16|RHEA:20629		molecular_function											owl:Class	
GO:0033421	biolink:NamedThing	CCU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CCU codon.	got7fsn_ti	proline tRNA|CCT codon-amino acid adaptor activity				Note that in the standard genetic code, CCT codes for proline.									molecular_function											owl:Class	
GO:0003846	biolink:NamedThing	2-acylglycerol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.	got7fsn_ti	acylglycerol palmitoyltransferase activity|acyl coenzyme A-monoglyceride acyltransferase activity|monoglyceride acyltransferase activity|acyl-CoA:2-acylglycerol O-acyltransferase activity|monoacylglycerol acyltransferase activity											Reactome:R-HSA-5696448|MetaCyc:2-ACYLGLYCEROL-O-ACYLTRANSFERASE-RXN|Reactome:R-HSA-6800334|RHEA:16741|EC:2.3.1.22		molecular_function											owl:Class	
GO:0018937	biolink:NamedThing	nitroglycerin metabolic process	The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates.	got7fsn_ti	nitroglycerin metabolism|NG metabolic process|NG metabolism											MetaCyc:P201-PWY|UM-BBD_pathwayID:ng		biological_process											owl:Class	
GO:0052914	biolink:NamedThing	16S rRNA (guanine(1207)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine.	got7fsn_ti	M(2)G1207 methyltransferase activity											RHEA:42736|MetaCyc:RXN-11576|EC:2.1.1.172|KEGG_REACTION:R07234		molecular_function											owl:Class	
GO:0047835	biolink:NamedThing	D-tryptophan N-acetyltransferase activity	Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H(+).	got7fsn_ti	D-tryptophan acetyltransferase activity|acetyl-CoA:D-tryptophan N-acetyltransferase activity|acetyl-CoA-D-tryptophan-alpha-N-acetyltransferase activity											EC:2.3.1.34|RHEA:10060|KEGG_REACTION:R02481|MetaCyc:D-TRYPTOPHAN-N-ACETYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0018041	biolink:NamedThing	C-terminal peptidyl-glycine amidation	The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein.	got7fsn_ti												RESID:AA0088		biological_process											owl:Class	
GO:0043782	biolink:NamedThing	cobalt-precorrin-3 C17-methyltransferase activity	Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine.	got7fsn_ti	cobalt-precorrin-3 methylase|cobalt-precorrin-3B C17-methyltransferase activity|cobalt-precorrin-3 methyltransferase|cobalt-precorrin 3 C17-methyltransferase activity											RHEA:26273|MetaCyc:RXN-8761		molecular_function											owl:Class	
GO:0070912	biolink:NamedThing	Ddb1-Ckn1 complex	A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.	got7fsn_ti							mah	2009-09-09T03:41:04Z						cellular_component											owl:Class	
GO:0036149	biolink:NamedThing	phosphatidylinositol acyl-chain remodeling	Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.	got7fsn_ti							bf	2012-03-14T01:27:02Z						biological_process											owl:Class	
GO:0002435	biolink:NamedThing	immune complex clearance by erythrocytes	The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation.	got7fsn_ti	immune complex clearance by RBCs|immune complex clearance by red blood cells	https://github.com/geneontology/go-ontology/issues/19884										Wikipedia:Immune_complex		biological_process											owl:Class	
GO:0043337	biolink:NamedThing	CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity	Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol.	got7fsn_ti	cardiolipin synthetase|cardiolipin synthase											Reactome:R-HSA-1483063|RHEA:32931|MetaCyc:RXN-8141		molecular_function											owl:Class	
GO:0097453	biolink:NamedThing	mesaxon	Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide.	got7fsn_ti	mesaxon of Schwann cell						pr	2012-12-19T12:59:13Z				NIF_Subcellular:sao2127666702		cellular_component											owl:Class	
GO:0035179	biolink:NamedThing	larval turning behavior	Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.	got7fsn_ti	larval turning behaviour													biological_process											owl:Class	
GO:0052726	biolink:NamedThing	inositol-1,3,4-trisphosphate 5-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+).	got7fsn_ti	inositol 1,3,4-trisphosphate 5-kinase activity|IP3 5-kinase activity|1D-myo-inositol-trisphosphate 5-kinase activity|ins(1,3,4)P(3) 5-kinase activity|ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase activity|Ins(1,3,4)P3 5-kinase activity|inositol-trisphosphate 5-kinase activity						ai	2011-08-16T12:43:11Z				EC:2.7.1.159|Reactome:R-HSA-1855172|KEGG_REACTION:R03428|Reactome:R-HSA-994140|MetaCyc:2.7.1.139-RXN|RHEA:13253		molecular_function											owl:Class	
GO:0033770	biolink:NamedThing	2-hydroxyisoflavanone synthase activity	Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O.	got7fsn_ti	2-HIS|apigenin,NADPH:oxygen oxidoreductase (isoflavanone-forming) activity											EC:1.14.13.86|RHEA:14897|MetaCyc:RXN-7750		molecular_function											owl:Class	
GO:0003075	biolink:NamedThing	renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure	The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system.	got7fsn_ti	renal regulation of systemic arterial blood pressure by vasodilation of the peripheral vascular system													biological_process											owl:Class	
GO:0102276	biolink:NamedThing	2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity	Catalysis of the reaction: 2-oxoglutarate(2-) + O2 + 2 H+ <=> ethene + 3 carbon dioxide + H2O.	got7fsn_ti												RHEA:31523|EC:1.13.12.19|MetaCyc:RXN-12538		molecular_function											owl:Class	
GO:0043707	biolink:NamedThing	cell adhesion involved in single-species biofilm formation in or on host organism	The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species.	got7fsn_ti	cell adhesion during single-species biofilm formation in or on host organism													biological_process											owl:Class	
GO:0018893	biolink:NamedThing	dibenzofuran metabolic process	The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals.	got7fsn_ti	dibenzofuran metabolism											UM-BBD_pathwayID:dbf		biological_process											owl:Class	
GO:0050149	biolink:NamedThing	o-aminophenol oxidase activity	Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O.	got7fsn_ti	GriF|2-aminophenol:O2 oxidoreductase activity|o-aminophenol:O2 oxidoreductase activity|2-aminophenol:oxygen oxidoreductase activity|isophenoxazine synthase activity											MetaCyc:O-AMINOPHENOL-OXIDASE-RXN|EC:1.10.3.4|RHEA:40963		molecular_function											owl:Class	
GO:0033961	biolink:NamedThing	cis-stilbene-oxide hydrolase activity	Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.	got7fsn_ti	aryl epoxide hydrase activity|benzo(a)pyrene-4,5-epoxide hydratase activity|microsomal epoxide hydratase activity|benzo[a]pyrene-4,5-oxide hydratase activity|epoxide hydrase activity|mEH|microsomal epoxide hydrase activity|microsomal epoxide hydrolase activity|epoxide hydratase activity|cis-epoxide hydrolase activity|arene-oxide hydratase activity											MetaCyc:3.3.2.9-RXN|Reactome:R-HSA-5694077|RHEA:23900|EC:3.3.2.9		molecular_function											owl:Class	
GO:0102906	biolink:NamedThing	7-epi-alpha-selinene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (-)-7-epi-alpha-selinene + diphosphoric acid.	got7fsn_ti												RHEA:30383|EC:4.2.3.86|MetaCyc:RXN-8609		molecular_function											owl:Class	
GO:0036321	biolink:NamedThing	ghrelin secretion	The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone.	got7fsn_ti	pancreatic ghrelin secretion						bf	2012-09-04T14:16:43Z						biological_process											owl:Class	
GO:0033796	biolink:NamedThing	sulfur reductase activity	Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide.	got7fsn_ti	sulphur reductase activity|(donor):sulfur oxidoreductase activity											MetaCyc:RXN-8269|MetaCyc:1.97.1.3-RXN|EC:1.12.98.4|RHEA:35591		molecular_function											owl:Class	
GO:0008108	biolink:NamedThing	UDP-glucose:hexose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.	got7fsn_ti	uridyl transferase activity|uridyltransferase activity|uridylyl removing enzyme activity|UDP-glucose-hexose-1-phosphate uridylyltransferase activity|Gal-1-P uridylyltransferase activity|galactose-1-phosphate uridylyltransferase activity|UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase activity|UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase activity|hexose-1-phosphate uridylyltransferase activity|UDPglucose-hexose-1-phosphate uridylyltransferase activity|hexose 1-phosphate uridyltransferase activity											MetaCyc:GALACTURIDYLYLTRANS-RXN|KEGG_REACTION:R00955|Reactome:R-HSA-70361|EC:2.7.7.12|Reactome:R-HSA-5610038|RHEA:13989		molecular_function											owl:Class	
GO:0008208	biolink:NamedThing	C21-steroid hormone catabolic process	The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.	got7fsn_ti	C21-steroid hormone degradation|C21-steroid hormone catabolism|C21-steroid hormone breakdown													biological_process											owl:Class	
GO:0045303	biolink:NamedThing	diaminobutyrate-2-oxoglutarate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate.	got7fsn_ti	2,4-diaminobutyrate 4-aminotransferase activity|diaminibutyric acid aminotransferase activity|L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity|L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity|EctB|L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity|diaminobutyrate transaminase activity|DAB aminotransferase activity|DABA aminotransferase activity|diaminobutyrate--2-oxoglutarate aminotransferase activity											RHEA:11160|KEGG_REACTION:R06977|MetaCyc:R101-RXN|EC:2.6.1.76		molecular_function											owl:Class	
GO:0006924	biolink:NamedThing	activation-induced cell death of T cells	A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.	got7fsn_ti	activation-induced cell death of T-cells|antigen-driven apoptosis|activation-induced cell death of T-lymphocytes|activation-induced cell death of T lymphocytes|AICD|activated T cell apoptosis													biological_process											owl:Class	
GO:0052913	biolink:NamedThing	16S rRNA (guanine(966)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine.	got7fsn_ti												EC:2.1.1.171|MetaCyc:RXN0-6515|KEGG_REACTION:R07234|RHEA:23548		molecular_function											owl:Class	
GO:0102639	biolink:NamedThing	paspalicine synthase activity	Catalysis of the reaction: 13-desoxypaxilline + NADPH + O2 + H+ <=> paspalicine + NADP + 2 H2O.	got7fsn_ti												MetaCyc:RXN-15737		molecular_function											owl:Class	
GO:0043780	biolink:NamedThing	cobalt-precorrin-5B C1-methyltransferase activity	Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A.	got7fsn_ti	cobalt-precorrin 5B C1-methyltransferase activity											MetaCyc:RXN-8764|RHEA:26285		molecular_function											owl:Class	
GO:0098864	biolink:NamedThing	modification by symbiont of host tight cell-cell junction	The process in which a symbiont organism effects a change in the structure or function of its host tight junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.	got7fsn_ti														biological_process											owl:Class	
GO:1990487	biolink:NamedThing	anaerobic lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units.	got7fsn_ti	anaerobic lignin degradation						tt	2014-09-20T17:35:09Z						biological_process											owl:Class	
GO:0046274	biolink:NamedThing	lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units.	got7fsn_ti	lignin degradation|lignin catabolism|lignin breakdown													biological_process											owl:Class	
GO:0009753	biolink:NamedThing	response to jasmonic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.	got7fsn_ti	response to jasmonic acid stimulus													biological_process											owl:Class	
GO:0018527	biolink:NamedThing	cyclohexylamine oxidase activity	Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide.	got7fsn_ti	cyclohexylamine:oxygen oxidoreductase (deaminating)											MetaCyc:CYCLOHEXYLAMINE-OXIDASE-RXN|UM-BBD_reactionID:r0754|EC:1.4.3.12|RHEA:18433		molecular_function											owl:Class	
GO:0018517	biolink:NamedThing	phthalate 4,5-cis-dihydrodiol dehydrogenase activity	Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH.	got7fsn_ti	cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase activity											MetaCyc:1.3.1.64-RXN|EC:1.3.1.64|RHEA:13837|KEGG_REACTION:R05275|UM-BBD_reactionID:r0142		molecular_function											owl:Class	
GO:0016656	biolink:NamedThing	monodehydroascorbate reductase (NADH) activity	Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.	got7fsn_ti	NADH:ascorbate radical oxidoreductase activity|NADH-semidehydroascorbate oxidoreductase activity|MDHA|SDA reductase activity|ascorbic free radical reductase activity|monodehydroascorbate reductase activity|NADH:semidehydroascorbic acid oxidoreductase activity|AFR|MDAsA reductase (NADPH)|semidehydroascorbate reductase activity|AFR-reductase activity|ascorbate free-radical reductase activity|ascorbate free radical reductase activity|NADH:AFR oxidoreductase activity|NADH:monodehydroascorbate oxidoreductase activity											RHEA:14581|MetaCyc:1.6.5.4-RXN|EC:1.6.5.4		molecular_function											owl:Class	
GO:0004573	biolink:NamedThing	mannosyl-oligosaccharide glucosidase activity	Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).	got7fsn_ti	processing A-glucosidase I activity|Glc3Man9NAc2 oligosaccharide glucosidase activity|trimming glucosidase I|mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity|mannosyl-oligosaccharide glucohydrolase activity											Reactome:R-HSA-532678|Reactome:R-HSA-4793947|RHEA:55988|EC:3.2.1.106|Reactome:R-HSA-9694364|MetaCyc:3.2.1.106-RXN		molecular_function											owl:Class	
GO:1990244	biolink:NamedThing	histone kinase activity (H2A-T120 specific)	Catalysis of the transfer of a phosphate group to the threonine-120 residue of histone H2A.	got7fsn_ti	histone threonine kinase activity (H2A-T120 specific)						sp	2013-12-04T06:38:32Z						molecular_function											owl:Class	
GO:0033250	biolink:NamedThing	penicillinase activity	Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.	got7fsn_ti												MetaCyc:BETA-LACTAMASE-RXN		molecular_function											owl:Class	
GO:0006432	biolink:NamedThing	phenylalanyl-tRNA aminoacylation	The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a  class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	got7fsn_ti														biological_process											owl:Class	
GO:0007434	biolink:NamedThing	adult salivary gland boundary specification	Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.	got7fsn_ti	larval salivary gland determination													biological_process											owl:Class	
GO:0044652	biolink:NamedThing	adhesion of symbiont to host endothelial cell	The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.	got7fsn_ti							jl	2012-07-12T12:49:07Z						biological_process											owl:Class	
GO:0001566	biolink:NamedThing	non-kinase phorbol ester receptor activity	Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0061184	biolink:NamedThing	positive regulation of dermatome development	Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.	got7fsn_ti							dph	2010-07-14T08:42:03Z						biological_process											owl:Class	
GO:0032882	biolink:NamedThing	regulation of chitin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.	got7fsn_ti	regulation of chitin metabolism													biological_process											owl:Class	
GO:0018127	biolink:NamedThing	NAD(P)-serine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine.	got7fsn_ti														molecular_function											owl:Class	
GO:0033814	biolink:NamedThing	propanoyl-CoA C-acyltransferase activity	Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.	got7fsn_ti	PTE-2|SCP-X|sterol carrier protein-chi|peroxisomal thiolase 2 activity|sterol carrier protein-X|SCPchi|3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity											EC:2.3.1.176|MetaCyc:2.3.1.176-RXN|RHEA:16865		molecular_function											owl:Class	
GO:0015381	biolink:NamedThing	high-affinity sulfate transmembrane transporter activity	Enables the secondary active high affinity transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations.	got7fsn_ti	high affinity sulphate permease activity|high affinity sulfate permease activity|high affinity sulfate transmembrane transporter activity													molecular_function											owl:Class	
GO:0008271	biolink:NamedThing	secondary active sulfate transmembrane transporter activity	Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	sulphate porter activity|sulfate porter activity|secondary active sulphate transmembrane transporter activity													molecular_function											owl:Class	
GO:0033715	biolink:NamedThing	nucleoside oxidase activity	Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O.	got7fsn_ti	nucleoside:oxygen 5'-oxidoreductase activity											EC:1.1.3.28|MetaCyc:NUCLEOSIDE-OXIDASE-RXN|RHEA:28651		molecular_function											owl:Class	
GO:0043904	biolink:NamedThing	isochorismate pyruvate lyase activity	Catalysis of the reaction: isochorismate = salicylate + pyruvate.	got7fsn_ti	IPL|isochorismate-pyruvate lyase activity											MetaCyc:RXN-1981|RHEA:27874|EC:4.2.99.21		molecular_function											owl:Class	
GO:0102679	biolink:NamedThing	(5alpha)-campestan-3-one hydroxylase activity	Catalysis of the reaction: H+ + (5alpha)-campestan-3-one + O2 + NADPH <=> (5alpha,22S,24R)-22-hydroxyergostan-3-one + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-4230		molecular_function											owl:Class	
GO:0019672	biolink:NamedThing	ethanol-acetate fermentation to butyrate and caproate	The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP.	got7fsn_ti														biological_process											owl:Class	
GO:0050899	biolink:NamedThing	nitrile catabolic process	The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.	got7fsn_ti	nitrile catabolism|nitrile breakdown|nitrile degradation													biological_process											owl:Class	
GO:0047426	biolink:NamedThing	ricinine nitrilase activity	Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone.	got7fsn_ti	ricinine aminohydrolase activity											RHEA:22704|EC:3.5.5.2|MetaCyc:3.5.5.2-RXN		molecular_function											owl:Class	
GO:0018524	biolink:NamedThing	acetophenone carboxylase activity	Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate.	got7fsn_ti											GO:0018797	EC:6.4.1.-|UM-BBD_reactionID:r0033		molecular_function											owl:Class	
GO:0002467	biolink:NamedThing	germinal center formation	The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.	got7fsn_ti														biological_process											owl:Class	
GO:0031770	biolink:NamedThing	growth hormone-releasing hormone receptor binding	Binding to a growth hormone-releasing hormone receptor.	got7fsn_ti	growth hormone-releasing hormone receptor ligand													molecular_function											owl:Class	
GO:0046618	biolink:NamedThing	xenobiotic export	The directed movement of a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	got7fsn_ti	drug export	https://github.com/geneontology/go-ontology/issues/19460												biological_process											owl:Class	
GO:0102405	biolink:NamedThing	(+)-taxifolin 5'-hydroxylase activity	Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ <=> (+)-dihydromyricetin + NADP(3-) + H2O.	got7fsn_ti												MetaCyc:RXN-13718|RHEA:61116		molecular_function											owl:Class	
GO:0034914	biolink:NamedThing	trinitrophenol hydride denitratase activity	Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP.	got7fsn_ti	TNP hydride denitratase activity|2,4,6-trinitrophenol hydride denitratase activity											EC:1.7.99.-|UM-BBD_reactionID:r1448		molecular_function											owl:Class	
GO:1990739	biolink:NamedThing	granulosa cell proliferation	The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge.	got7fsn_ti							sl	2015-05-06T18:56:04Z						biological_process											owl:Class	
GO:0004966	biolink:NamedThing	galanin receptor activity	Combining with galanin to initiate a change in cell activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0036531	biolink:NamedThing	glutathione deglycation	The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine.	got7fsn_ti							bf	2016-08-04T10:45:27Z						biological_process											owl:Class	
GO:0018849	biolink:NamedThing	muconate cycloisomerase activity	Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.	got7fsn_ti	cis,cis-muconate cycloisomerase activity|muconate lactonizing enzyme I activity|muconate cycloisomerase I activity|muconate lactonizing enzyme activity|cis,cis-muconate-lactonizing enzyme	https://github.com/geneontology/go-ontology/issues/21794										EC:5.5.1.1|UM-BBD_enzymeID:e0133|MetaCyc:MUCONATE-CYCLOISOMERASE-RXN|RHEA:30031		molecular_function											owl:Class	
GO:0001179	biolink:NamedThing	RNA polymerase I general transcription initiation factor binding	Binding to an RNA polymerase I transcription factor, a protein required to initiate or regulate transcription by RNA polymerase I.	got7fsn_ti	RNA polymerase I transcription factor binding						krc	2011-08-12T03:03:03Z						molecular_function											owl:Class	
GO:0072647	biolink:NamedThing	interferon-epsilon production	The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IFN-epsilon production|interferon-epsilon secretion|IFNE production				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072648			biological_process											owl:Class	
GO:0048578	biolink:NamedThing	positive regulation of long-day photoperiodism, flowering	Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	got7fsn_ti	activation of long-day photoperiodism, flowering|up regulation of long-day photoperiodism, flowering|stimulation of long-day photoperiodism, flowering|upregulation of long-day photoperiodism, flowering|up-regulation of long-day photoperiodism, flowering													biological_process											owl:Class	
GO:0052934	biolink:NamedThing	alcohol dehydrogenase (cytochrome c) activity	Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+.	got7fsn_ti	alcohol:cytochrome c oxidoreductase activity|alcohol dehydrogenase (acceptor) activity|ethanol:cytochrome c oxidoreductase activity|alcohol:(acceptor) oxidoreductase activity|alcohol:acceptor oxidoreductase activity|quinoprotein alcohol dehydrogenase activity|2-chloroethanol:cytochrome c oxidoreductase activity|PQQ-dependent alcohol dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/21412									GO:0052936|GO:0052935|GO:0018468	RHEA:51020|KEGG_REACTION:R05198|MetaCyc:RXN-11333|EC:1.1.2.8|KEGG_REACTION:R05285|UM-BBD_enzymeID:e0004		molecular_function											owl:Class	
GO:0035931	biolink:NamedThing	mineralocorticoid secretion	The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism.	got7fsn_ti							bf	2011-07-20T01:04:59Z						biological_process											owl:Class	
GO:0070681	biolink:NamedThing	glutaminyl-tRNAGln biosynthesis via transamidation	A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.	got7fsn_ti							mah	2009-06-02T03:15:57Z				MetaCyc:PWY-5921		biological_process											owl:Class	
GO:0047740	biolink:NamedThing	cephalosporin-C transaminase activity	Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C.	got7fsn_ti	L-alanine:cephalosporin-C aminotransferase activity|cephalosporin-C:2-oxoglutarate aminotransferase activity|cephalosporin C aminotransferase activity											KEGG_REACTION:R03063|RHEA:14553|EC:2.6.1.74|MetaCyc:CEPHALOSPORIN-C-TRANSAMINASE-RXN		molecular_function											owl:Class	
GO:0033639	biolink:NamedThing	modulation by symbiont of host response to water	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0033635	biolink:NamedThing	modulation by symbiont of host response to abiotic stimulus	Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0019640	biolink:NamedThing	glucuronate catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.	got7fsn_ti	glucuronate degradation to xylulose 5-phosphate|glucuronate breakdown to xylulose 5-phosphate													biological_process											owl:Class	
GO:0102483	biolink:NamedThing	scopolin beta-glucosidase activity	Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.	got7fsn_ti												MetaCyc:RXN-14179|EC:3.2.1.21		molecular_function											owl:Class	
GO:0004410	biolink:NamedThing	homocitrate synthase activity	Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H(2)O = CoA + H(+) + homocitrate.	got7fsn_ti	acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity|2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity|acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)|2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)|homocitrate synthetase activity				Note that this function was formerly EC:4.1.3.21.							MetaCyc:HOMOCITRATE-SYNTHASE-RXN|RHEA:12929|EC:2.3.3.14|KEGG_REACTION:R00271		molecular_function											owl:Class	
GO:0042997	biolink:NamedThing	negative regulation of Golgi to plasma membrane protein transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.	got7fsn_ti	downregulation of Golgi to plasma membrane protein transport|down regulation of Golgi to plasma membrane protein transport|inhibition of Golgi to plasma membrane protein transport|down-regulation of Golgi to plasma membrane protein transport													biological_process											owl:Class	
GO:0009366	biolink:NamedThing	enterobactin synthetase complex	A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway.	got7fsn_ti	enterochelin synthetase complex											MetaCyc:ENTMULTI-CPLX		cellular_component											owl:Class	
GO:0003825	biolink:NamedThing	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.	got7fsn_ti	UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|trehalose 6-phosphate synthetase activity|UDP-glucose-glucose-phosphate glucosyltransferase activity|uridine diphosphoglucose phosphate glucosyltransferase activity|trehalose 6-phosphate synthase activity|alpha,alpha-trehalose phosphate synthase (UDP-forming)|UDPglucose-glucose-phosphate glucosyltransferase activity|UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|UDP-glucose-glucosephosphate glucosyltransferase activity|trehalosephosphate-UDP glucosyl transferase activity|trehalose-P synthetase activity|trehalose phosphate synthase activity|trehalose-phosphate synthetase activity|transglucosylase activity|trehalose phosphate synthetase activity|trehalosephosphate-UDP glucosyltransferase activity|trehalose-phosphate synthase activity|phosphotrehalose-uridine diphosphate transglucosylase activity|trehalose phosphate-uridine diphosphate glucosyltransferase activity											EC:2.4.1.15|MetaCyc:TREHALOSE6PSYN-RXN|RHEA:18889		molecular_function											owl:Class	
GO:0047356	biolink:NamedThing	CDP-ribitol ribitolphosphotransferase activity	Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP.	got7fsn_ti	teichoic-acid synthase activity|teichoate synthetase activity|poly(ribitol phosphate) synthetase activity|CDPribitol ribitolphosphotransferase activity|polyribitol phosphate synthetase activity|polyribitol phosphate polymerase activity|CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase activity|teichoate synthase activity											RHEA:13353|EC:2.7.8.14|MetaCyc:2.7.8.14-RXN		molecular_function											owl:Class	
GO:0015939	biolink:NamedThing	pantothenate metabolic process	The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	got7fsn_ti	vitamin B5 metabolism|vitamin B5 metabolic process|pantothenate metabolism										GO:0006770			biological_process											owl:Class	
GO:0016287	biolink:NamedThing	glycerone-phosphate O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA.	got7fsn_ti	acyl-CoA:glycerone-phosphate O-acyltransferase activity|dihydroxyacetone phosphate acyltransferase activity											Reactome:R-HSA-75879|KEGG_REACTION:R01013|EC:2.3.1.42|MetaCyc:2.3.1.42-RXN|Reactome:R-HSA-1483002|RHEA:17657		molecular_function											owl:Class	
GO:0080071	biolink:NamedThing	indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate.	got7fsn_ti							dhl	2009-04-13T04:08:33Z				MetaCyc:RXN-1443		molecular_function											owl:Class	
GO:0036518	biolink:NamedThing	chemorepulsion of dopaminergic neuron axon	The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.	got7fsn_ti	chemorepulsion of dopaminergic axon|chemorepulsion of DA axon						bf	2015-12-17T11:29:09Z						biological_process											owl:Class	
GO:0032090	biolink:NamedThing	Pyrin domain binding	Binding to a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain.	got7fsn_ti	DAPIN domain binding|PAAD domain binding													molecular_function											owl:Class	
GO:0062055	biolink:NamedThing	photosynthetic state transition	A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems.	got7fsn_ti							dph	2018-07-16T14:00:57Z						biological_process											owl:Class	
GO:0036512	biolink:NamedThing	trimming of second mannose on A branch	The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.	got7fsn_ti	conversion of M8A to M7AA|conversion of (Man)8A(GlcNAc)2 to (Man)7AA(GlcNAc)2|glycoprotein mannose trimming on A branch				Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T14:16:40Z						biological_process											owl:Class	
GO:0018059	biolink:NamedThing	N-terminal peptidyl-serine deamination	The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.	got7fsn_ti														biological_process											owl:Class	
GO:0061911	biolink:NamedThing	amphisome-lysosome fusion	The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome.	got7fsn_ti							dph	2017-07-05T18:54:52Z						biological_process											owl:Class	
GO:0102438	biolink:NamedThing	laricitrin 4'-O-methyltransferase activity	Catalysis of the reaction: laricitrin(1-) + S-adenosyl-L-methionine  <=> H+ + 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-13914		molecular_function											owl:Class	
GO:0042468	biolink:NamedThing	klinokinesis	The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered.	got7fsn_ti														biological_process											owl:Class	
GO:0102528	biolink:NamedThing	7,8,4'-trihydroxyflavone methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 7,8,4'-trihydroxyflavone <=> H+ + S-adenosyl-L-homocysteine  + 7,4'-dihydroxy, 8-methoxyflavone.	got7fsn_ti												MetaCyc:RXN-14658		molecular_function											owl:Class	
GO:0018664	biolink:NamedThing	benzoate 4-monooxygenase activity	Catalysis of the reaction: benzoate + H(+) + NADPH + O(2) = 4-hydroxybenzoate + H(2)O + NADP(+).	got7fsn_ti	benzoic 4-hydroxylase activity|benzoate 4-hydroxylase activity|benzoic acid 4-hydroxylase activity|p-hydroxybenzoate hydroxylase activity|benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)|benzoate-para-hydroxylase activity|benzoate-p-hydroxylase activity|4-hydroxybenzoic hydroxylase activity											EC:1.14.14.92|MetaCyc:BENZOATE-4-MONOOXYGENASE-RXN|KEGG_REACTION:R01295|UM-BBD_reactionID:r0623|RHEA:18033		molecular_function											owl:Class	
GO:0034520	biolink:NamedThing	2-naphthaldehyde dehydrogenase activity	Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+.	got7fsn_ti												UM-BBD_reactionID:r0772|EC:1.2.1.-		molecular_function											owl:Class	
GO:0034534	biolink:NamedThing	1-methylnaphthalene hydroxylase activity	Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O.	got7fsn_ti												UM-BBD_reactionID:r0795|EC:1.14.13.-		molecular_function											owl:Class	
GO:0006581	biolink:NamedThing	acetylcholine catabolic process	The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline.	got7fsn_ti	acetylcholine degradation|acetylcholine catabolism|acetylcholine breakdown													biological_process											owl:Class	
GO:0008727	biolink:NamedThing	GDP-mannose mannosyl hydrolase activity	Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+.	got7fsn_ti												MetaCyc:GDPMANMANHYDRO-RXN|RHEA:28102		molecular_function											owl:Class	
GO:0033001	biolink:NamedThing	Fc-gamma receptor III complex	A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.	got7fsn_ti	FcgRIII complex|immunoglobulin G receptor complex|IgG receptor complex													cellular_component											owl:Class	
GO:0034788	biolink:NamedThing	2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+.	got7fsn_ti												UM-BBD_reactionID:r1041		molecular_function											owl:Class	
GO:1900550	biolink:NamedThing	N',N'',N'''-triacetylfusarinine C catabolic process	The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C.	got7fsn_ti	N',N'',N'''-triacetylfusarinine C catabolism|N',N'',N'''-triacetylfusarinine C degradation|N',N'',N'''-triacetylfusarinine C breakdown						di	2012-05-15T01:00:07Z						biological_process											owl:Class	
GO:0102317	biolink:NamedThing	4-methylaminobutyrate oxidase (demethylating) activity	Catalysis of the reaction: 4-(methylamino)butyric acid  + O2 + H2O <=> gamma-aminobutyric acid  + formaldehyde + hydrogen peroxide.	got7fsn_ti												MetaCyc:RXN-13067|EC:1.5.3.19|RHEA:33907		molecular_function											owl:Class	
GO:0050282	biolink:NamedThing	serine 2-dehydrogenase activity	Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH.	got7fsn_ti	L-serine:NAD oxidoreductase (deaminating) activity|L-serine:NAD+ 2-oxidoreductase (deaminating)|serine dehydrogenase activity											MetaCyc:SERINE-DEHYDROGENASE-RXN|EC:1.4.1.7|RHEA:20884		molecular_function											owl:Class	
GO:0004706	biolink:NamedThing	JUN kinase kinase kinase activity	Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs).	got7fsn_ti	JNKKK|JNK kinase kinase activity													molecular_function											owl:Class	
GO:0062071	biolink:NamedThing	Pi Mi complex	A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis.	got7fsn_ti							dph	2018-09-04T13:40:52Z						cellular_component											owl:Class	
GO:1990574	biolink:NamedThing	meiotic spindle astral microtubule	Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.	got7fsn_ti							vw	2014-12-04T09:55:09Z						cellular_component											owl:Class	
GO:0033590	biolink:NamedThing	response to cobalamin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.	got7fsn_ti	response to vitamin B12													biological_process											owl:Class	
GO:0004415	biolink:NamedThing	hyalurononglucosaminidase activity	Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.	got7fsn_ti	hyaluronoglucosidase activity|hyaluronidase activity|chondroitinase activity|chondroitinase I activity|hyaluronoglucosaminidase activity|hyaluronate 4-glycanohydrolase activity											Reactome:R-HSA-1793209|EC:3.2.1.35|MetaCyc:3.2.1.35-RXN|Reactome:R-HSA-2160874|Reactome:R-HSA-5693356|Reactome:R-HSA-2160892|Reactome:R-HSA-9036077|Reactome:R-HSA-2318585		molecular_function											owl:Class	
GO:2000256	biolink:NamedThing	positive regulation of male germ cell proliferation	Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.	got7fsn_ti							dph	2010-11-18T09:29:50Z						biological_process											owl:Class	
GO:0043800	biolink:NamedThing	hexulose-6-phosphate isomerase activity	Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate.	got7fsn_ti	HUMPI											EC:5.3.1.27|MetaCyc:R12-RXN|RHEA:25900		molecular_function											owl:Class	
GO:0039697	biolink:NamedThing	negative stranded viral RNA transcription	A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template.	got7fsn_ti							bf	2013-10-28T14:41:41Z				VZ:1096		biological_process											owl:Class	
GO:0047389	biolink:NamedThing	glycerophosphocholine phosphodiesterase activity	Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.	got7fsn_ti	glycerophosphinicocholine diesterase activity|sn-glycero-3-phosphocholine glycerophosphohydrolase activity|glycerylphosphorylcholinediesterase activity|glycerophosphohydrolase activity|glycerolphosphorylcholine phosphodiesterase activity|sn-glycero-3-phosphorylcholine diesterase activity											Reactome:R-HSA-6814132|EC:3.1.4.2|MetaCyc:3.1.4.2-RXN|RHEA:16061		molecular_function											owl:Class	
GO:0043428	biolink:NamedThing	2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	got7fsn_ti	2-heptaprenyl-6-methoxy-1,4-benzoquinone methylase activity				Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.							MetaCyc:RXN-9227|RHEA:44756		molecular_function											owl:Class	
GO:0010735	biolink:NamedThing	positive regulation of transcription via serum response element binding	Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.	got7fsn_ti														biological_process											owl:Class	
GO:0062081	biolink:NamedThing	activating MHC class Ib receptor activity	Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte.	got7fsn_ti							dph	2018-10-15T15:05:07Z						molecular_function											owl:Class	
GO:0062122	biolink:NamedThing	histone methyltransferase activity (H3-K37 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group onto lysine at position 37 of the histone H3 protein.	got7fsn_ti	histone lysine N-methyltransferase activity (H3-K37 specific)						dph	2019-04-01T13:30:11Z						molecular_function											owl:Class	
GO:0009903	biolink:NamedThing	chloroplast avoidance movement	The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery.	got7fsn_ti	high-fluence-rate response													biological_process											owl:Class	
GO:0050089	biolink:NamedThing	mannose isomerase activity	Catalysis of the reaction: D-mannose = D-fructose.	got7fsn_ti	D-mannose aldose-ketose-isomerase activity|D-mannose ketol-isomerase activity|D-mannose isomerase activity											RHEA:22604|EC:5.3.1.7|KEGG_REACTION:R00877|MetaCyc:MANNOSE-ISOMERASE-RXN		molecular_function											owl:Class	
GO:1990678	biolink:NamedThing	histone H4-K16 deacetylation	The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone.	got7fsn_ti							al	2015-03-02T15:25:56Z						biological_process											owl:Class	
GO:0071911	biolink:NamedThing	synchronous neurotransmitter secretion	Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.	got7fsn_ti							mah	2010-09-22T01:38:36Z						biological_process											owl:Class	
GO:0052610	biolink:NamedThing	beta-cryptoxanthin hydroxylase activity	Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O.	got7fsn_ti	carotene beta-ring hydroxylase activity|beta-carotene hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity											RHEA:30327|MetaCyc:RXN-8026		molecular_function											owl:Class	
GO:0046790	biolink:NamedThing	virion binding	Binding to a virion, either by binding to components of the capsid or the viral envelope.	got7fsn_ti														molecular_function											owl:Class	
GO:0018606	biolink:NamedThing	benzenesulfonate dioxygenase activity	Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.	got7fsn_ti	benzenesulphonate dioxygenase activity											EC:1.14.12.-|UM-BBD_reactionID:r0295		molecular_function											owl:Class	
GO:0033900	biolink:NamedThing	ribonuclease F activity	Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups.	got7fsn_ti	ribonuclease F (E. coli) activity|RNase F activity											EC:3.1.27.7|MetaCyc:3.1.27.7-RXN		molecular_function											owl:Class	
GO:0004144	biolink:NamedThing	diacylglycerol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.	got7fsn_ti	palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity|diglyceride acyltransferase activity|diacylglycerol acyltransferase activity|acyl-CoA:1,2-diacylglycerol O-acyltransferase activity|1,2-diacylglycerol acyltransferase activity|diglyceride O-acyltransferase activity											RHEA:10868|Reactome:R-HSA-75900|MetaCyc:DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN|EC:2.3.1.20|Reactome:R-HSA-8848580|Reactome:R-HSA-1482889|Reactome:R-HSA-549192		molecular_function											owl:Class	
GO:0014715	biolink:NamedThing	myoblast fate commitment in trunk	The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0033797	biolink:NamedThing	selenate reductase activity	Catalysis of the reaction: 2 e(-) + 2 H(+) + selenate = H(2)O + selenite.	got7fsn_ti	selenite:reduced acceptor oxidoreductase activity											KEGG_REACTION:R07229|EC:1.97.1.9|UM-BBD_reactionID:r0828|RHEA:14029|MetaCyc:RXN0-2101		molecular_function											owl:Class	
GO:0102261	biolink:NamedThing	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity	Catalysis of the reaction: NADP + a reduced coenzyme F420 <=> NADPH + H+ + an oxidized coenzyme F420.	got7fsn_ti												RHEA:31363|MetaCyc:RXN-12450|EC:1.5.1.40		molecular_function											owl:Class	
GO:0097303	biolink:NamedThing	lipoprotein biosynthetic process via N-acyl transfer	The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex.	got7fsn_ti	lipoprotein biosynthesis (N-acyl transfer)						pr	2012-05-15T01:03:59Z						biological_process											owl:Class	
GO:0098607	biolink:NamedThing	methylselenocysteine deselenhydrase activity	Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol.	got7fsn_ti							dos	2014-04-16T11:24:12Z				Reactome:R-HSA-2408539		molecular_function											owl:Class	
GO:0102464	biolink:NamedThing	zeaxanthin 2-beta-hydroxylase activity	Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ <=> caloxanthin + H2O + NAD.	got7fsn_ti												MetaCyc:RXN-14016		molecular_function											owl:Class	
GO:0032986	biolink:NamedThing	protein-DNA complex disassembly	The disaggregation of a protein-DNA complex into its constituent components.	got7fsn_ti	DNA-protein complex disassembly													biological_process											owl:Class	
GO:0097039	biolink:NamedThing	protein linear polyubiquitination	A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.	got7fsn_ti	M1 linkage						pr	2011-04-13T01:52:51Z						biological_process											owl:Class	
GO:0021657	biolink:NamedThing	rhombomere 2 formation	The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	got7fsn_ti														biological_process											owl:Class	
GO:0106322	biolink:NamedThing	S-(hydroxymethyl)glutathione dehydrogenase NAD activity	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD+ = S-formylglutathione + NADH + H+.	got7fsn_ti							hjd	2020-09-23T15:26:40Z				RHEA:19985|EC:1.1.1.284		molecular_function											owl:Class	
GO:0005044	biolink:NamedThing	scavenger receptor activity	Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).	got7fsn_ti	macrophage receptor activity				Note that many gene products that are called scavenger receptors have a broad range of potential ligands and also can be annotated to 'pattern recognition receptor activity ; GO:0038187' or its child terms, or to 'lipoprotein receptor activity ; GO:0030228' or its child terms. For receptors that transduce a signal rather than endocytose their ligand, consider instead the terms 'signaling receptor activity ; GO:0038023' and its children.									molecular_function											owl:Class	
GO:0035522	biolink:NamedThing	monoubiquitinated histone H2A deubiquitination	The removal of the ubiquitin group from a monoubiquitinated histone H2A protein.	got7fsn_ti	monoubiquitinated histone H2A deubiquitinylation|monoubiquitinated histone H2A deubiquitylation						bf	2010-05-04T04:32:53Z						biological_process											owl:Class	
GO:0004613	biolink:NamedThing	phosphoenolpyruvate carboxykinase (GTP) activity	Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2.	got7fsn_ti	phosphopyruvate carboxylase (GTP)|phosphoenolpyruvic carboxykinase (GTP)|phosphoenolpyruvic carboxylase (GTP)|phosphoenolpyruvate carboxylase (GTP)|GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming)|GTP:oxaloacetate carboxy-lyase (transphosphorylating)|phosphopyruvate (guanosine triphosphate) carboxykinase activity|phosphoenolpyruvic carboxykinase											RHEA:10388|Reactome:R-HSA-70241|EC:4.1.1.32|Reactome:R-HSA-372819|MetaCyc:4.1.1.32-RXN		molecular_function											owl:Class	
GO:0048361	biolink:NamedThing	root epithelial mucilage metabolic process	The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.	got7fsn_ti	root epithelial mucilage metabolism													biological_process											owl:Class	
GO:0051680	biolink:NamedThing	6-alpha-maltosylglucose biosynthetic process	The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose.	got7fsn_ti	isopanose biosynthesis|isopanose biosynthetic process													biological_process											owl:Class	
GO:0004776	biolink:NamedThing	succinate-CoA ligase (GDP-forming) activity	Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate.	got7fsn_ti	succinyl coenzyme A synthetase|succinic thiokinase|succinyl CoA synthetase activity|succinate-phosphorylating enzyme|succinyl coenzyme A synthetase (guanosine diphosphate-forming) activity|P-enzyme|succinyl-CoA synthetase (GDP-forming) activity|succinate:CoA ligase (GDP-forming) activity|succinyl coenzyme A synthetase (GDP-forming) activity|G-STK|SCS											Reactome:R-HSA-71775|MetaCyc:SUCCINATE--COA-LIGASE-GDP-FORMING-RXN|EC:6.2.1.4|RHEA:22120|KEGG_REACTION:R00432		molecular_function											owl:Class	
GO:0047365	biolink:NamedThing	quercetin-3-sulfate 3'-sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,3'-disulfate.	got7fsn_ti	flavonol 3'-sulfotransferase activity|quercetin-3-sulphate 3'-sulphotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 3'-sulfotransferase activity|3'-sulfotransferase activity|PAPS:flavonol 3-sulfate 3'-sulfotransferase activity											KEGG_REACTION:R02632|MetaCyc:2.8.2.26-RXN|EC:2.8.2.26|RHEA:22504		molecular_function											owl:Class	
GO:0004343	biolink:NamedThing	glucosamine 6-phosphate N-acetyltransferase activity	Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+).	got7fsn_ti	D-glucosamine-6-P N-acetyltransferase activity|acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase activity|glucosamine-6-phosphate acetylase activity|N-acetylglucosamine-6-phosphate synthase activity|phosphoglucosamine N-acetylase activity|glucosamine 6-phosphate acetylase activity|glucosamine-phosphate N-acetyltransferase activity|aminodeoxyglucosephosphate acetyltransferase activity|phosphoglucosamine acetylase activity|phosphoglucosamine transacetylase activity											EC:2.3.1.4|MetaCyc:GLUCOSAMINEPNACETYLTRANS-RXN|RHEA:10292|KEGG_REACTION:R02058|Reactome:R-HSA-449734		molecular_function											owl:Class	
GO:0061821	biolink:NamedThing	telomeric D-loop binding	Binding to a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.	got7fsn_ti	telomeric Displacement-loop binding						dph							molecular_function											owl:Class	
GO:0034668	biolink:NamedThing	integrin alpha4-beta1 complex	An integrin complex that comprises one alpha4 subunit and one beta1 subunit.	got7fsn_ti	alpha4-beta1 integrin complex|VLA-4 complex|ITGA4-ITGB1 complex													cellular_component											owl:Class	
GO:0050064	biolink:NamedThing	luteolin 7-O-glucuronosyltransferase activity	Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP.	got7fsn_ti	luteolin 7-O-glucoronosyltransferase activity|uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase activity|UDP-glucuronate:luteolin 7-O-glucuronosyltransferase activity|LGT|UDPglucuronate:luteolin 7-O-glucuronosyltransferase activity											KEGG_REACTION:R03589|EC:2.4.1.189|RHEA:10568|MetaCyc:LUTEOLIN-7-O-GLUCORONOSYLTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0052823	biolink:NamedThing	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity	Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+.	got7fsn_ti	2-hydroxy-6-ketonona-2,4,7-trienedoic acid hydrolase activity|(2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate fumarylhydrolase activity						ai	2011-10-28T03:28:37Z				EC:3.7.1.14|MetaCyc:RXN-12070|RHEA:25046|UM-BBD_reactionID:r1622		molecular_function											owl:Class	
GO:0021929	biolink:NamedThing	stellate cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0018444	biolink:NamedThing	translation release factor complex	A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome.	got7fsn_ti	eukaryotic peptide chain release factor|peptide chain release factor													cellular_component											owl:Class	
GO:0031423	biolink:NamedThing	hexon binding	Binding to a hexon, the major protein component of the icosahedral capsid of an adenovirus.	got7fsn_ti														molecular_function											owl:Class	
GO:0036088	biolink:NamedThing	D-serine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.	got7fsn_ti	D-serine catabolism|D-serine degradation|D-serine breakdown						bf	2012-01-06T10:58:51Z						biological_process											owl:Class	
GO:0030516	biolink:NamedThing	regulation of axon extension	Any process that modulates the rate, direction or extent of axon extension.	got7fsn_ti														biological_process											owl:Class	
GO:0046679	biolink:NamedThing	response to streptomycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.	got7fsn_ti	streptomycin susceptibility/resistance													biological_process											owl:Class	
GO:0102236	biolink:NamedThing	trans-4-hexen-3-one reductase activity	Catalysis of the reaction: trans-4-hexen-3-one + NADPH + H+ <=> hexan-3-one + NADP.	got7fsn_ti												MetaCyc:RXN-12296		molecular_function											owl:Class	
GO:0102532	biolink:NamedThing	genkwanin 6-hydroxylase activity	Catalysis of the reaction: genkwanin + O2 + NADPH + H+ <=> scutellarein 7-methyl ether + H2O + NADP.	got7fsn_ti												MetaCyc:RXN-14748		molecular_function											owl:Class	
GO:0047265	biolink:NamedThing	poly(glycerol-phosphate) alpha-glucosyltransferase activity	Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP.	got7fsn_ti	UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity|UDPglucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity|UDP-glucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity|uridine diphosphoglucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity											MetaCyc:2.4.1.52-RXN|EC:2.4.1.52|RHEA:15845		molecular_function											owl:Class	
GO:0033932	biolink:NamedThing	1,3-alpha-L-fucosidase activity	Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.	got7fsn_ti	3-alpha-L-fucosyl-N-acetylglucosaminyl-glycoprotein fucohydrolase activity|almond emulsin fucosidase I activity											MetaCyc:3.2.1.111-RXN|EC:3.2.1.111		molecular_function											owl:Class	
GO:0120138	biolink:NamedThing	regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.	got7fsn_ti							krc	2018-03-22T16:15:08Z						biological_process											owl:Class	
GO:0033698	biolink:NamedThing	Rpd3L complex	A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae).	got7fsn_ti	Clr6L complex|Clr6 histone deacetylase complex I/I'|Rpd3C(L)										GO:0000508			cellular_component											owl:Class	
GO:0046429	biolink:NamedThing	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin.	got7fsn_ti	(E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase activity|1-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase activity|1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase activity|(E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized ferredoxin oxidoreductase activity											MetaCyc:RXN0-882|RHEA:26119|KEGG_REACTION:R08689|EC:1.17.7.1		molecular_function											owl:Class	
GO:0098994	biolink:NamedThing	disruption of host cell envelope during viral entry	The disruption of host cell envelope by viral proteins during virus entry.	got7fsn_ti												VZ:3938		biological_process											owl:Class	
GO:0090577	biolink:NamedThing	RNA polymerase IV transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV.	got7fsn_ti	RNA polymerase IV transcription factor complex						tb	2014-05-09T14:04:37Z						cellular_component											owl:Class	
GO:0043906	biolink:NamedThing	Ala-tRNA(Pro) hydrolase activity	Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro).	got7fsn_ti	Ala-tRNAPro hydrolase activity											EC:3.1.1.-		molecular_function											owl:Class	
GO:0019162	biolink:NamedThing	pyridoxamine-oxaloacetate transaminase activity	Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal.	got7fsn_ti	pyridoxamine--oxaloacetate aminotransferase activity|pyridoxamine:oxaloacetate aminotransferase activity|pyridoxamine-oxaloacetate aminotransferase activity											MetaCyc:PYROXALTRANSAM-RXN|EC:2.6.1.31|KEGG_REACTION:R01713|RHEA:10844		molecular_function											owl:Class	
GO:1990828	biolink:NamedThing	hepatocyte dedifferentiation	The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.	got7fsn_ti							sl	2015-08-20T14:14:57Z						biological_process											owl:Class	
GO:0004310	biolink:NamedThing	farnesyl-diphosphate farnesyltransferase activity	Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.	got7fsn_ti	presqualene-diphosphate synthase activity|presqualene synthase activity|farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity				Note that the two reactions performed by EC:2.5.1.21 are represented in GO by 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310' and 'squalene synthase activity ; GO:0051996'.							Reactome:R-HSA-191405|MetaCyc:2.5.1.21-RXN|Reactome:R-HSA-191402|EC:2.5.1.21		molecular_function											owl:Class	
GO:0047662	biolink:NamedThing	aminobenzoate decarboxylase activity	Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2.	got7fsn_ti	aminobenzoate carboxy-lyase (aniline-forming)|aminobenzoate carboxy-lyase activity											EC:4.1.1.24|MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN|RHEA:24200		molecular_function											owl:Class	
GO:0033890	biolink:NamedThing	ribonuclease D activity	Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.	got7fsn_ti	RNase D activity											EC:3.1.13.5|MetaCyc:3.1.13.5-RXN		molecular_function											owl:Class	
GO:0047423	biolink:NamedThing	N-methylhydantoinase (ATP-hydrolyzing) activity	Catalysis of the reaction: N-methylhydantoin + ATP + 2 H(2)O = N-carbamoylsarcosine + ADP + 3 H(+) + phosphate.	got7fsn_ti	N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing)|N-methylhydantoinase (ATP-hydrolysing)|N-methylhydantoinase activity|methylhydantoin amidase activity|N-methylhydantoin hydrolase activity|N-methylhydantoin amidohydrolase activity											Wikipedia:N-methylhydantoinase_(ATP-hydrolysing)|KEGG_REACTION:R03187|RHEA:11720|EC:3.5.2.14|MetaCyc:3.5.2.14-RXN		molecular_function											owl:Class	
GO:0021810	biolink:NamedThing	neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration	Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration.	got7fsn_ti	neurotransmitter signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0071208	biolink:NamedThing	histone pre-mRNA DCP binding	Binding to the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing.	got7fsn_ti							mah	2009-11-25T01:41:35Z						molecular_function											owl:Class	
GO:0034186	biolink:NamedThing	apolipoprotein A-I binding	Binding to apolipoprotein A-I.	got7fsn_ti														molecular_function											owl:Class	
GO:0034418	biolink:NamedThing	urate biosynthetic process	The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine.	got7fsn_ti	urate biosynthesis|urate synthesis|uric acid biosynthetic process|urate anabolism|urate formation													biological_process											owl:Class	
GO:0102051	biolink:NamedThing	indole-3-acetyl-tryptophan synthetase activity	Catalysis of the reaction: indole-3-acetate + L-tryptophan + ATP(4-) <=> H+ + indole-3-acetyl-tryptophan + AMP(2-) + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-10433		molecular_function											owl:Class	
GO:0047922	biolink:NamedThing	gentisate 1,2-dioxygenase activity	Catalysis of the reaction: 2,5-dihydroxybenzoate + O(2) = 3-maleylpyruvate + H(+).	got7fsn_ti	2,5-dihydroxybenzoate dioxygenase activity|gentisate dioxygenase activity|gentisate:oxygen 1,2-oxidoreductase (decyclizing)|gentisate oxygenase activity|gentisic acid oxidase activity											RHEA:18237|KEGG_REACTION:R02656|MetaCyc:GENTISATE-12-DIOXYGENASE-RXN|EC:1.13.11.4		molecular_function											owl:Class	
GO:0071210	biolink:NamedThing	protein insertion into membrane raft	The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	got7fsn_ti	establishment of protein localization to membrane raft						mah	2009-11-25T02:11:46Z						biological_process											owl:Class	
GO:0000091	biolink:NamedThing	mitotic anaphase A	The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis.	got7fsn_ti					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0062130	biolink:NamedThing	adhesive extracellular matrix	A extracellular matrix which attaches an organism to a substrate.	got7fsn_ti	puparial glue						dph	2019-06-21T12:35:06Z						cellular_component											owl:Class	
GO:1990448	biolink:NamedThing	exon-exon junction complex binding	Binding to an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.	got7fsn_ti	EJC binding						sart	2014-08-06T10:02:46Z						molecular_function											owl:Class	
GO:0031464	biolink:NamedThing	Cul4A-RING E3 ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.	got7fsn_ti	SCF4 complex|CDL4 complex|VDC complex|cullin-RING ligase 4A|CRL4 complex|DCX complex													cellular_component											owl:Class	
GO:0010276	biolink:NamedThing	phytol kinase activity	Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+.	got7fsn_ti												EC:2.7.1.182|RHEA:38055|MetaCyc:RXN-7683		molecular_function											owl:Class	
GO:1990309	biolink:NamedThing	type-II dockerin domain binding	Binding to a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain.	got7fsn_ti							tt	2014-03-07T03:16:49Z						molecular_function											owl:Class	
GO:0022020	biolink:NamedThing	medial ganglionic eminence cell proliferation	The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
GO:0050798	biolink:NamedThing	activated T cell proliferation	The expansion of a T cell population following activation by an antigenic stimulus.	got7fsn_ti	activated T-cell proliferation|activated T lymphocyte proliferation|activated T-lymphocyte proliferation|proliferation of activated T cells				Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells.									biological_process											owl:Class	
GO:0047317	biolink:NamedThing	N6-acetyl-beta-lysine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate.	got7fsn_ti	6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase activity|epsilon-acetyl-beta-lysine aminotransferase activity|N(6)-acetyl-beta-lysine aminotransferase activity|N6-acetyl-beta-lysine aminotransferase activity											RHEA:16889|MetaCyc:2.6.1.65-RXN|EC:2.6.1.65		molecular_function											owl:Class	
GO:0047605	biolink:NamedThing	acetolactate decarboxylase activity	Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2.	got7fsn_ti	alpha-acetolactate decarboxylase activity|(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming]|(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase activity											MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN|RHEA:21580|EC:4.1.1.5		molecular_function											owl:Class	
GO:0000831	biolink:NamedThing	inositol hexakisphosphate 6-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0008330	biolink:NamedThing	protein tyrosine/threonine phosphatase activity	Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0003121	biolink:NamedThing	epinephrine-mediated vasodilation	A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings.	got7fsn_ti	regulation of vasodilation by neuronal epinephrine|regulation of vasodilation by adrenaline|regulation of vasodilation by epinephrine|regulation of vasodilation by circulating adrenaline|regulation of vasodilation by neuronal adrenaline|regulation of vasodilation by circulating epinephrine										GO:0003123|GO:0003124			biological_process											owl:Class	
GO:0102670	biolink:NamedThing	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity	Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine  <=> H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine.	got7fsn_ti												RHEA:31371|EC:2.1.1.212|MetaCyc:RXN-3624		molecular_function											owl:Class	
GO:0031762	biolink:NamedThing	follicle-stimulating hormone receptor binding	Binding to a follicle-stimulating hormone receptor.	got7fsn_ti	follicle stimulating hormone receptor ligand|follicle stimulating hormone receptor binding|FSH receptor binding													molecular_function											owl:Class	
GO:0061567	biolink:NamedThing	dCMP phosphorylation	The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP.	got7fsn_ti							dph	2013-08-01T12:54:21Z						biological_process											owl:Class	
GO:0004639	biolink:NamedThing	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate.	got7fsn_ti	SAICARs activity|SAICAR synthetase activity|SAICAR synthase activity|4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)|phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity|5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity|4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity|phosphoribosylaminoimidazole-succinocarboxamide synthase activity|PurC|phosphoribosylaminoimidazole-succinocarboxamide synthetase activity|4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity											Reactome:R-HSA-73805|RHEA:22628|MetaCyc:SAICARSYN-RXN|EC:6.3.2.6|KEGG_REACTION:R04591		molecular_function											owl:Class	
GO:0050343	biolink:NamedThing	trans-2-enoyl-CoA reductase (NAD+) activity	Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH.	got7fsn_ti	acyl-CoA:NAD+ trans-2-oxidoreductase activity											EC:1.3.1.44|MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN|RHEA:18177		molecular_function											owl:Class	
GO:0061477	biolink:NamedThing	response to aromatase inhibitor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.	got7fsn_ti							dph	2012-11-07T09:08:36Z						biological_process											owl:Class	
GO:0033794	biolink:NamedThing	sarcosine reductase activity	Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin.	got7fsn_ti	acetyl-phosphate methylamine:thioredoxin disulfide oxidoreductase (N-methylglycine-forming) activity											EC:1.21.4.3|RHEA:12825		molecular_function											owl:Class	
GO:0044527	biolink:NamedThing	formation of peptidyl-cystine persulfide by sulphur transfer from H2S	The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide.	got7fsn_ti							jl	2012-03-15T09:46:23Z						biological_process											owl:Class	
GO:0016540	biolink:NamedThing	protein autoprocessing	Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.	got7fsn_ti														biological_process											owl:Class	
GO:0030639	biolink:NamedThing	polyketide biosynthetic process	The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.	got7fsn_ti	polyketide formation|polyketide synthesis|polyketide biosynthesis|polyketide anabolism													biological_process											owl:Class	
GO:0097076	biolink:NamedThing	transforming growth factor beta activated kinase 1 complex	A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits).	got7fsn_ti	TAK1 kinase complex						pr	2011-06-15T04:55:32Z						cellular_component											owl:Class	
GO:0098677	biolink:NamedThing	virion maturation	Maturation of a virion after separation from the host cell. Not all viruses mature after separation.  In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection.	got7fsn_ti	virus particle maturation|viral particle maturation						dos	2017-01-19T12:49:22Z				UniProtKB-KW:KW-0917|VZ:1946		biological_process											owl:Class	
GO:0005175	biolink:NamedThing	CD27 receptor binding	Binding to a CD27, a receptor found on the surface of T cells and some B cells and NK cells.	got7fsn_ti														molecular_function											owl:Class	
GO:2000141	biolink:NamedThing	positive regulation of octopamine signaling pathway involved in response to food	Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food.	got7fsn_ti	positive regulation of octopamine signalling pathway involved in response to food						mah	2010-09-30T02:48:12Z						biological_process											owl:Class	
GO:0032216	biolink:NamedThing	glucosaminyl-phosphatidylinositol O-acyltransferase activity	Catalysis of the reaction: glucosaminyl-phosphatidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phasphotidylinositol + CoA.	got7fsn_ti	glucosaminyl-phosphotidylinositol O-acyltransferase activity|GPI-inositol acyltransferase													molecular_function											owl:Class	
GO:0001955	biolink:NamedThing	blood vessel maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.	got7fsn_ti														biological_process											owl:Class	
GO:0047137	biolink:NamedThing	N-hydroxy-2-acetamidofluorene reductase activity	Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+.	got7fsn_ti	N-hydroxy-2-acetylaminofluorene reductase activity|2-acetamidofluorene:NAD(P)+ oxidoreductase activity|NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity|NAD(P)H2:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity											EC:1.7.1.12|MetaCyc:1.7.1.12-RXN		molecular_function											owl:Class	
GO:0102804	biolink:NamedThing	oripavine 6-O-demethylase activity	Catalysis of the reaction: oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-8151|EC:1.14.11.31		molecular_function											owl:Class	
GO:0047575	biolink:NamedThing	4-carboxymuconolactone decarboxylase activity	Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = 5-oxo-4,5-dihydro-2-furylacetate + CO(2).	got7fsn_ti	4-carboxymuconolactone carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming)|gamma-4-carboxymuconolactone decarboxylase activity|4-carboxymonolactone carboxy-lyase activity|4-carboxymuconolactone carboxy-lyase activity											RHEA:23348|KEGG_REACTION:R03470|EC:4.1.1.44|MetaCyc:4-CARBOXYMUCONOLACTONE-DECARBOXYLASE-RXN		molecular_function											owl:Class	
GO:0018492	biolink:NamedThing	carbon-monoxide dehydrogenase (acceptor) activity	Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor.	got7fsn_ti	carbon-monoxide:acceptor oxidoreductase activity|carbon monoxide dehydrogenase activity|anaerobic carbon monoxide dehydrogenase activity											EC:1.2.7.4|RHEA:21040|UM-BBD_enzymeID:e0415|MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN		molecular_function											owl:Class	
GO:1904126	biolink:NamedThing	convergent extension involved in notochord morphogenesis	Any convergent extension that is involved in notochord morphogenesis.	got7fsn_ti							dph	2015-04-10T21:12:57Z						biological_process											owl:Class	
GO:0071547	biolink:NamedThing	piP-body	A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.	got7fsn_ti							mah	2010-01-12T05:47:47Z						cellular_component											owl:Class	
GO:0106309	biolink:NamedThing	progesterone 21-hydroxylase activity	Catalysis of the reaction: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							hjd	2020-09-21T14:40:30Z				RHEA:50304		molecular_function											owl:Class	
GO:0120171	biolink:NamedThing	Cdc24p-Far1p-Gbetagamma complex	A complex that forms at the cell cortex in response to pheromone treatment and is required for the polarized growth of haploid yeast cells towards a mating partner during yeast mating. In the yeast Saccharomyces cerevisiae, this complex consists of Cdc24p, Far1p, Ste4p (G-protein beta subunit) and Ste18p (G-protein gamma subunit).	got7fsn_ti	Cdc24p-Far1p-BG complex|CDC24-FAR1-BG complex|CDC24-FAR1-Gbetagamma complex						krc	2018-05-31T17:11:20Z						cellular_component											owl:Class	
GO:1990485	biolink:NamedThing	anaerobic lactate catabolic process	The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.	got7fsn_ti	anaerobic lactic acid catabolic process						tt	2014-09-20T16:48:06Z						biological_process											owl:Class	
GO:0099141	biolink:NamedThing	cellular response to protozoan	Any process that results in a change in state or activity of a cell  (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.	got7fsn_ti														biological_process											owl:Class	
GO:0075138	biolink:NamedThing	response to host oxygen tension environment	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response of symbiont to host oxygen tension environment				Note that this term is used to annotate gene products of the symbiont.									biological_process											owl:Class	
GO:0098515	biolink:NamedThing	detection of low humidity stimulus involved in sensory perception	The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity.	got7fsn_ti							dos	2013-09-25T14:24:29Z						biological_process											owl:Class	
GO:0019948	biolink:NamedThing	SUMO activating enzyme activity	Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.	got7fsn_ti	SUMO E1 activator enzyme|SMT3 activating enzyme										GO:0017115	Reactome:R-HSA-2990833|Reactome:R-HSA-2993781|Reactome:R-HSA-2993784		molecular_function											owl:Class	
GO:0003786	biolink:NamedThing	actin lateral binding	Binding to an actin filament along its length.	got7fsn_ti														molecular_function											owl:Class	
GO:0061227	biolink:NamedThing	pattern specification involved in mesonephros development	Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.	got7fsn_ti	mesonephros pattern formation|mesonephros pattern specification						dph	2010-08-19T02:22:22Z						biological_process											owl:Class	
GO:0052088	biolink:NamedThing	symbiont defense to host-produced jasmonic acid	Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related host jasmonic acid-mediated signal transduction pathway|inhibition by symbiont of host jasmonic acid-mediated defense response|induction by organism of defense-related host SA-mediated signal transduction pathway|activation by organism of defense-related host SA-mediated signal transduction pathway|modulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|down regulation by symbiont of host jasmonic acid-mediated defense response|upregulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|activation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related host jasmonic acid-mediated signal transduction pathway|downregulation by symbiont of host jasmonic acid-mediated defense response|positive regulation by organism of defense-related host SA-mediated signal transduction pathway|induction by organism of defense-related host jasmonic acid-mediated signal transduction pathway|suppression by organism of host JA-mediated defense response|positive regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|negative regulation by symbiont of host jasmonic acid-mediated defense response|suppression by symbiont of host jasmonic acid-mediated defense response|negative regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|induction by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related host SA-mediated signal transduction pathway|up-regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|up regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|down-regulation by symbiont of host jasmonic acid-mediated defense response|modulation by organism of host JA-mediated defense response|negative regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|stimulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway	https://github.com/geneontology/go-ontology/issues/18798									GO:0052082|GO:0052073|GO:0052266|GO:0052068|GO:0052271|GO:0052267|GO:0052069|GO:0052443|GO:0052283			biological_process											owl:Class	
GO:0140337	biolink:NamedThing	diacylglyceride transfer activity	Directly binding to diacylglyceride and delivering it either to an acceptor molecule or to a specific location.	got7fsn_ti	diacylglyceride carrier activity						pg	2019-05-16T11:28:08Z						molecular_function											owl:Class	
GO:0034932	biolink:NamedThing	1-methoxypyrene 6,7-monooxygenase activity	Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O.	got7fsn_ti												UM-BBD_reactionID:r0954		molecular_function											owl:Class	
GO:0004530	biolink:NamedThing	deoxyribonuclease I activity	Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.	got7fsn_ti	DNase activity|alkaline DNase activity|DNase I|DNA nuclease activity|DNA endonuclease activity|endodeoxyribonuclease I|pancreatic dornase|deoxyribonuclease (pancreatic)|thymonuclease activity|dornavac|DNAase activity|pancreatic deoxyribonuclease|thymonuclease, dornase activity|deoxyribonucleic phosphatase activity|alkaline deoxyribonuclease activity|deoxyribonuclease A|Escherichia coli endonuclease I|dornava|DNA depolymerase activity|pancreatic DNase activity											MetaCyc:3.1.21.1-RXN|EC:3.1.21.1		molecular_function											owl:Class	
GO:0018965	biolink:NamedThing	s-triazine compound metabolic process	The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.	got7fsn_ti	s-triazine compound metabolism											UM-BBD_pathwayID:tria		biological_process											owl:Class	
GO:0099609	biolink:NamedThing	microtubule lateral binding	Binding to the side of a microtubule.	got7fsn_ti														molecular_function											owl:Class	
GO:0046462	biolink:NamedThing	monoacylglycerol metabolic process	The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.	got7fsn_ti	monoacylglycerol metabolism|monoglyceride metabolic process|monoglyceride metabolism													biological_process											owl:Class	
GO:0033943	biolink:NamedThing	galactan 1,3-beta-galactosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans.	got7fsn_ti	galactan (1,3)-beta-D-galactosidase activity|galactan (1->3)-beta-D-galactosidase activity											MetaCyc:3.2.1.145-RXN|EC:3.2.1.145		molecular_function											owl:Class	
GO:0043758	biolink:NamedThing	acetate-CoA ligase (ADP-forming) activity	Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.	got7fsn_ti	acetate--CoA ligase (ADP-forming) activity|acetate:CoA ligase (ADP-forming)|acetate thiokinase activity|acetyl coenzyme A synthetase (adenosine diphosphate-forming)|acetyl-CoA synthetase (ADP-forming) activity|aryl-CoA synthetase (ADP-forming) activity										GO:0043762	RHEA:15081|MetaCyc:ACETATE--COA-LIGASE-ADP-FORMING-RXN|EC:6.2.1.13		molecular_function											owl:Class	
GO:0015915	biolink:NamedThing	fatty-acyl group transport	The directed movement of fatty acyl groups into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A fatty acyl group is any acyl group derived from a fatty acid.	got7fsn_ti	fatty acyl transport													biological_process											owl:Class	
GO:0045134	biolink:NamedThing	uridine-diphosphatase activity	Catalysis of the reaction: UDP + H2O = UMP + phosphate.	got7fsn_ti	uridine diphosphatase activity|UDPase activity|UDP phosphohydrolase activity|uridine 5'-diphosphatase activity											RHEA:64876|EC:3.6.1.6|KEGG_REACTION:R00155|MetaCyc:RXN-12197		molecular_function											owl:Class	
GO:0062083	biolink:NamedThing	HLA-G specific inhibitory MHC class Ib receptor activity	Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte.	got7fsn_ti							dph	2018-10-15T15:06:44Z						molecular_function											owl:Class	
GO:0036436	biolink:NamedThing	Isw1a complex	An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p.	got7fsn_ti							bf	2013-09-18T16:45:41Z						cellular_component											owl:Class	
GO:0102533	biolink:NamedThing	genkwanin 4'-O-methyltransferase activity	Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine  <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-14750		molecular_function											owl:Class	
GO:0005983	biolink:NamedThing	starch catabolic process	The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants.	got7fsn_ti	starch catabolism|starch breakdown|starch degradation											MetaCyc:PWY-842		biological_process											owl:Class	
GO:0031789	biolink:NamedThing	G protein-coupled acetylcholine receptor binding	Binding to a G protein-coupled acetylcholine receptor.	got7fsn_ti	M5 muscarinic acetylcholine receptor binding|M3 muscarinic acetylcholine receptor binding|M2 muscarinic acetylcholine receptor ligand|M4 muscarinic acetylcholine receptor binding|M2 muscarinic acetylcholine receptor binding|M5 muscarinic acetylcholine receptor ligand|G-protein coupled acetylcholine receptor binding|M1 muscarinic acetylcholine receptor binding|M3 muscarinic acetylcholine receptor ligand|M1 muscarinic acetylcholine receptor ligand|muscarinic acetylcholine receptor binding|muscarinic acetylcholine receptor ligand|M4 muscarinic acetylcholine receptor ligand										GO:0031791|GO:0031790|GO:0031793|GO:0031792|GO:0031794			molecular_function											owl:Class	
GO:0102619	biolink:NamedThing	oryzalexin C synthase (oryzalexin A dependent) activity	Catalysis of the reaction: oryzalexin A + NAD(P) <=> oryzalexin C + H+ + NAD(P)H.	got7fsn_ti												MetaCyc:RXN-15467		molecular_function											owl:Class	
GO:0043420	biolink:NamedThing	anthranilate metabolic process	The chemical reactions and pathways involving anthranilate (2-aminobenzoate).	got7fsn_ti	anthranilic acid metabolism|2-aminobenzoate metabolism|2-aminobenzoate metabolic process|ortho-aminobenzoic acid metabolic process|anthranilic acid metabolic process|ortho-aminobenzoic acid metabolism|anthranilate metabolism										GO:0018869	UM-BBD_pathwayID:abz2		biological_process											owl:Class	
GO:0106277	biolink:NamedThing	biliverdin reductase (NADP+) activity	Catalysis of the reaction: bilirubin + NADP+ = biliverdin + NADPH + H+.	got7fsn_ti							hjd	2020-07-02T01:50:24Z				RHEA:15793|EC:1.3.1.24		molecular_function											owl:Class	
GO:0062192	biolink:NamedThing	L-rhamnose mutarotase activity	Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose.	got7fsn_ti							dph	2019-12-09T16:45:45Z				RHEA:25584|EC:5.1.3.32		molecular_function											owl:Class	
GO:0070267	biolink:NamedThing	oncosis	A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death.	got7fsn_ti					Note that oncosis is sometimes described as a type of cell death, but recent nomenclature recommendations define it as a feature of necrotic cell death rather than a distinct mode of cell death.									biological_process											owl:Class	
GO:0061616	biolink:NamedThing	glycolytic process from fructose through fructose-6-phosphate	The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.	got7fsn_ti	glycolysis from fructose through fructose-6-phosphate						dph	2014-04-08T10:20:37Z				MetaCyc:PWY-5484		biological_process											owl:Class	
GO:0106326	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP.	got7fsn_ti							hjd	2020-09-30T13:40:25Z				RHEA:56192|EC:2.4.1.148		molecular_function											owl:Class	
GO:0019650	biolink:NamedThing	glycolytic fermentation to butanediol	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.	got7fsn_ti	glucose fermentation to butanediol|glucose catabolic process to butanediol|butanediol fermentation										GO:0030646	MetaCyc:P125-PWY|Wikipedia:Butanediol_fermentation		biological_process											owl:Class	
GO:1990082	biolink:NamedThing	DnaA-L2 complex	A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2.	got7fsn_ti							bhm	2013-04-30T11:46:41Z						cellular_component											owl:Class	
GO:0046961	biolink:NamedThing	proton-transporting ATPase activity, rotational mechanism	Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.	got7fsn_ti	F(1)-ATPase activity|F0F1-ATPase|F(o)F(1)-ATPase activity|ATP phosphohydrolase (H+-transporting) activity|ATP synthase activity|mitochondrial ATPase activity|hydrogen ion translocating F-type ATPase activity|hydrogen ion transporting ATPase activity, rotational mechanism|hydrogen ion translocating A-type ATPase activity|H+-transporting ATPase activity|FoF1-ATPase|hydrogen ion transporting two-sector ATPase activity|F(0)F(1)-ATPase activity|hydrogen ion translocating V-type ATPase activity|H(+)-transporting ATP synthase activity|chloroplast ATPase activity|F1-ATPase											EC:7.1.2.2|MetaCyc:ATPSYN-RXN|RHEA:57721		molecular_function											owl:Class	
GO:0043131	biolink:NamedThing	erythrocyte enucleation	The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation.	got7fsn_ti														biological_process											owl:Class	
GO:0048835	biolink:NamedThing	specification of decreased petal number	Any process that reduces the number of petals produced in a developing flower.	got7fsn_ti														biological_process											owl:Class	
GO:0050062	biolink:NamedThing	long-chain-fatty-acyl-CoA reductase activity	Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH.	got7fsn_ti	acyl coenzyme A reductase activity|long-chain fatty acyl CoA reductase activity|long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming)|long-chain fatty acyl-CoA reductase activity											EC:1.2.1.50|MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN|RHEA:15437		molecular_function											owl:Class	
GO:0090674	biolink:NamedThing	endothelial cell-matrix adhesion via fibronectin	The binding of an endothelial cell to the extracellular matrix via fibronectin.	got7fsn_ti							tb	2016-01-15T15:40:58Z						biological_process											owl:Class	
GO:0090673	biolink:NamedThing	endothelial cell-matrix adhesion	The binding of an endothelial cell to the extracellular matrix via adhesion molecules.	got7fsn_ti							tb	2016-01-15T15:38:11Z						biological_process											owl:Class	
GO:0062150	biolink:NamedThing	amorpha-4,11-diene 12-monooxygenase activity	Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							dph	2019-09-13T14:48:12Z				EC:1.14.14.114|RHEA:32999		molecular_function											owl:Class	
GO:0102330	biolink:NamedThing	palmitoyl-[acp] elongase/decarboxylase activity	Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-13258		molecular_function											owl:Class	
GO:0050235	biolink:NamedThing	pyridoxal 4-dehydrogenase activity	Catalysis of the reaction: NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH.	got7fsn_ti	pyridoxal dehydrogenase activity|pyridoxal:NAD+ 4-oxidoreductase activity											MetaCyc:PYRIDOXAL-4-DEHYDROGENASE-RXN|KEGG_REACTION:R01707|EC:1.1.1.107|RHEA:21336		molecular_function											owl:Class	
GO:0097412	biolink:NamedThing	hyaline inclusion	A glass-like, pale intracellular inclusion.	got7fsn_ti	pale body						pr	2012-11-06T16:24:58Z				NIF_Subcellular:nlx_subcell_20090104		cellular_component											owl:Class	
GO:0047991	biolink:NamedThing	hydroxylamine oxidase activity	Catalysis of the reaction: hydroxylamine + O(2) = H(2)O + H(+) + nitrite.	got7fsn_ti	hydroxylamine:oxygen oxidoreductase activity|HAO|hydroxylamine oxidoreductase											MetaCyc:HAONITRO-RXN|EC:1.7.3.6|RHEA:19969|KEGG_REACTION:R00793		molecular_function											owl:Class	
GO:0003992	biolink:NamedThing	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.	got7fsn_ti	acetylornithine transaminase activity|acetylornithine aminotransferase activity|N-acetylornithine-delta-transaminase activity|N2-acetylornithine 5-transaminase activity|succinylornithine aminotransferase activity|acetylornithine delta-transaminase activity|ACOAT activity|N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase activity|N-acetylornithine aminotransferase activity|acetylornithine 5-aminotransferase activity|N(2)-acetylornithine 5-transaminase activity|2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|N2-acetylornithine 5-aminotransferase activity										GO:0047318	MetaCyc:ACETYLORNTRANSAM-RXN|KEGG_REACTION:R02283|RHEA:18049|EC:2.6.1.11		molecular_function											owl:Class	
GO:0071741	biolink:NamedThing	IgD immunoglobulin complex, GPI-anchored	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells.	got7fsn_ti	GPI-anchored IgD				Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z						cellular_component											owl:Class	
GO:0031788	biolink:NamedThing	motilin receptor binding	Binding to a motilin receptor.	got7fsn_ti	motilin receptor ligand													molecular_function											owl:Class	
GO:0008821	biolink:NamedThing	crossover junction endodeoxyribonuclease activity	Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).	got7fsn_ti	crossover junction endoribonuclease activity|endo X3|Hje endonuclease activity|endodeoxyribonuclease RUS activity|SpCCe1 holliday junction resolvase|endonuclease X3 activity|Endo X3 activity|resolving enzyme CCE1 activity|Holliday junction resolvase activity|RusA endonuclease activity|Holliday junction nuclease activity|endonuclease VII activity|RuvC endonuclease activity|Holliday junction-cleaving endonuclease activity|RusA Holliday junction resolvase activity|SpCCe1 Holliday junction resolvase activity|RusA holliday junction resolvase|Holliday junction-resolving endoribonuclease activity|Holliday junction endonuclease CCE1 activity|cruciform-cutting endonuclease activity|endonuclease RuvC activity										GO:0008844	EC:3.1.22.4|MetaCyc:3.1.22.4-RXN		molecular_function											owl:Class	
GO:0035941	biolink:NamedThing	androstenedione secretion	The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system.	got7fsn_ti	androst-4-ene-3,17-dione secretion						bf	2011-07-25T02:11:47Z						biological_process											owl:Class	
GO:0070709	biolink:NamedThing	RNA guanosine insertion	The modification of an RNA molecule by insertion of a guanosine nucleotide.	got7fsn_ti	RNA G insertion						mah	2009-06-08T04:57:26Z						biological_process											owl:Class	
GO:0047746	biolink:NamedThing	chlorophyllase activity	Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide.	got7fsn_ti	chlorophyll chlorophyllidohydrolase activity											MetaCyc:CHLOROPHYLLASE-RXN|EC:3.1.1.14		molecular_function											owl:Class	
GO:0103027	biolink:NamedThing	FMN phosphatase activity	Catalysis of the reaction: FMN + H2O = riboflavin + hydrogenphosphate.	got7fsn_ti												MetaCyc:RXN0-5187		molecular_function											owl:Class	
GO:0036445	biolink:NamedThing	neuronal stem cell division	The self-renewing division of a neuronal stem cell.	got7fsn_ti	NSC division						bf	2013-10-30T10:03:27Z						biological_process											owl:Class	
GO:0048103	biolink:NamedThing	somatic stem cell division	The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.	got7fsn_ti	somatic stem cell renewal													biological_process											owl:Class	
GO:0008721	biolink:NamedThing	D-serine ammonia-lyase activity	Catalysis of the reaction: D-serine = pyruvate + NH3.	got7fsn_ti	D-serine deaminase activity|D-serine dehydratase activity|D-serine dehydration activity|D-serine dehydratase (deaminating) activity|D-serine ammonia-lyase (pyruvate-forming)|D-hydroxyaminoacid dehydratase activity|D-serine hydrolase activity|D-serine hydro-lyase (deaminating) activity|D-serine dehydrase activity|D-hydroxy amino acid dehydratase activity				Note that this function was formerly EC:4.3.1.14.							MetaCyc:DSERDEAM-RXN|Reactome:R-HSA-9034539|Reactome:R-HSA-9014741|RHEA:13977|EC:4.3.1.18		molecular_function											owl:Class	
GO:0072711	biolink:NamedThing	cellular response to hydroxyurea	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.	got7fsn_ti	cellular response to HU						mah	2012-04-11T04:15:56Z						biological_process											owl:Class	
GO:0103010	biolink:NamedThing	gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming)	Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-991		molecular_function											owl:Class	
GO:0051109	biolink:NamedThing	crotonobetaine-CoA ligase activity	Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA.	got7fsn_ti	crotonobetaine-CoA synthase activity|crotonobetaine/carnitine-CoA ligase activity											MetaCyc:CROTCOALIG-RXN|RHEA:30079		molecular_function											owl:Class	
GO:0051922	biolink:NamedThing	cholesterol sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate.	got7fsn_ti												EC:2.8.2.-		molecular_function											owl:Class	
GO:0002933	biolink:NamedThing	lipid hydroxylation	The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.	got7fsn_ti	fatty acid hydroxylation						hjd	2012-04-24T02:26:33Z						biological_process											owl:Class	
GO:0008785	biolink:NamedThing	alkyl hydroperoxide reductase activity	Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol.	got7fsn_ti												UM-BBD_reactionID:r0684|Reactome:R-HSA-1222526		molecular_function											owl:Class	
GO:0051371	biolink:NamedThing	muscle alpha-actinin binding	Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.	got7fsn_ti	alpha-actinin 3 binding|alpha-actinin 2 binding													molecular_function											owl:Class	
GO:0004572	biolink:NamedThing	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity	Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).	got7fsn_ti	alpha-mannosidase II|mannosidase II activity|mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity|GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase activity|exo-1,3-1,6-alpha-mannosidase activity|Golgi alpha-mannosidase II|alpha-(1,3/6)-mannosidase activity|1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase activity|mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity|ManII activity|mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity|alpha-D-mannosidase II											MetaCyc:3.2.1.114-RXN|RHEA:56052|EC:3.2.1.114|Reactome:R-HSA-975814		molecular_function											owl:Class	
GO:0006189	biolink:NamedThing	'de novo' IMP biosynthetic process	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.	got7fsn_ti	'de novo' purine biosynthetic process|'de novo' IMP synthesis|'de novo' IMP biosynthesis|'de novo' purine biosynthesis|'de novo' IMP anabolism|'de novo' IMP formation													biological_process											owl:Class	
GO:0043840	biolink:NamedThing	branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine.	got7fsn_ti	branched-chain-amino-acid:2-keto-4-methylthiobutyrate aminotransferase activity|branched-chain amino acid aminotransferase|branched chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity|BCAT											MetaCyc:RXN-7708		molecular_function											owl:Class	
GO:1990275	biolink:NamedThing	preribosome binding	Binding to a preribosome.	got7fsn_ti							tb	2014-01-16T19:14:50Z						molecular_function											owl:Class	
GO:0089716	biolink:NamedThing	Pip2-Oaf1 complex	A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:2000035	biolink:NamedThing	regulation of stem cell division	Any process that modulates the frequency, rate or extent of stem cell division.	got7fsn_ti	regulation of stem cell renewal						tb	2010-08-05T11:34:53Z						biological_process											owl:Class	
GO:0035154	biolink:NamedThing	terminal cell fate specification, open tracheal system	The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.	got7fsn_ti	terminal cell fate specification													biological_process											owl:Class	
GO:0047978	biolink:NamedThing	hexadecanol dehydrogenase activity	Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH.	got7fsn_ti	hexadecanol:NAD+ oxidoreductase activity											EC:1.1.1.164|MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN|RHEA:22056		molecular_function											owl:Class	
GO:0042276	biolink:NamedThing	error-prone translesion synthesis	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites.	got7fsn_ti	error-prone postreplication DNA repair|mutagenic postreplication DNA repair|mutagenic PRR													biological_process											owl:Class	
GO:0045820	biolink:NamedThing	negative regulation of glycolytic process	Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.	got7fsn_ti	down-regulation of glycolysis|downregulation of glycolysis|inhibition of glycolysis|down regulation of glycolysis													biological_process											owl:Class	
GO:0102935	biolink:NamedThing	gypsogenin-UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-9012		molecular_function											owl:Class	
GO:0000806	biolink:NamedThing	Y chromosome	The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males.	got7fsn_ti												Wikipedia:Y_chromosome		cellular_component											owl:Class	
GO:0050557	biolink:NamedThing	deacetylipecoside synthase activity	Catalysis of the reaction: deacetylipecoside + H(2)O = dopamine + secologanin.	got7fsn_ti	deacetylipecoside dopamine-lyase (secologanin-forming)|deacetylipecoside dopamine-lyase activity											EC:4.3.3.4|KEGG_REACTION:R05749|RHEA:12296|MetaCyc:4.3.3.4-RXN		molecular_function											owl:Class	
GO:0034314	biolink:NamedThing	Arp2/3 complex-mediated actin nucleation	The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.	got7fsn_ti	branched actin filament nucleation|actin filament branch nucleation													biological_process											owl:Class	
GO:0006221	biolink:NamedThing	pyrimidine nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine nucleotide formation|pyrimidine nucleotide synthesis|pyrimidine nucleotide biosynthesis|pyrimidine nucleotide anabolism													biological_process											owl:Class	
GO:0052770	biolink:NamedThing	coenzyme F390-A hydrolase activity	Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420.	got7fsn_ti	8-hydroxyadenylylated-coenzyme F420 hydrolase activity						ai	2011-10-03T12:00:00Z						molecular_function											owl:Class	
GO:1990281	biolink:NamedThing	efflux pump complex	A protein complex that is capable of efflux transmembrane transporter activity.	got7fsn_ti	efflux transmembrane transporter complex|efflux pump						tt	2014-01-31T08:19:53Z						cellular_component											owl:Class	
GO:0019716	biolink:NamedThing	N-terminal peptidyl-alanine monomethylation	The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine.	got7fsn_ti												RESID:AA0061		biological_process											owl:Class	
GO:0090475	biolink:NamedThing	lys-lys specific dibasic protein processing	Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein.	got7fsn_ti							tb	2012-10-01T10:42:30Z						biological_process											owl:Class	
GO:0140572	biolink:NamedThing	vacuole fission	The division of a vacuole within a cell to form two or more separate vacuoles.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20639					pg	2021-01-04T10:17:58Z						biological_process											owl:Class	
GO:0050551	biolink:NamedThing	myrcene synthase activity	Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene.	got7fsn_ti	geranyl-diphosphate diphosphate-lyase (myrcene-forming) activity											KEGG_REACTION:R02009|RHEA:16965|MetaCyc:RXN-5110|EC:4.2.3.15		molecular_function											owl:Class	
GO:0010507	biolink:NamedThing	negative regulation of autophagy	Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	got7fsn_ti														biological_process											owl:Class	
GO:0106046	biolink:NamedThing	guanine deglycation, glyoxal removal	The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine.	got7fsn_ti							hjd	2017-08-01T18:19:30Z						biological_process											owl:Class	
GO:0046125	biolink:NamedThing	pyrimidine deoxyribonucleoside metabolic process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	pyrimidine deoxyribonucleoside metabolism													biological_process											owl:Class	
GO:0050033	biolink:NamedThing	L-rhamnono-1,4-lactonase activity	Catalysis of the reaction: L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate + H(+).	got7fsn_ti	L-rhamnono-1,4-lactone lactonohydrolase activity|L-rhamnono-gamma-lactonase activity|L-rhamno-gamma-lactonase activity											RHEA:10288|MetaCyc:L-RHAMNONO-14-LACTONASE-RXN|EC:3.1.1.65|KEGG_REACTION:R03772		molecular_function											owl:Class	
GO:0103028	biolink:NamedThing	murein hydrolase activity	Catalysis of the reaction: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide.	got7fsn_ti												MetaCyc:RXN0-5190		molecular_function											owl:Class	
GO:0043453	biolink:NamedThing	alkyne biosynthetic process	The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.	got7fsn_ti	alkyne synthesis|alkyne formation|alkyne anabolism|alkyne biosynthesis													biological_process											owl:Class	
GO:0006031	biolink:NamedThing	chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.	got7fsn_ti	chitin biosynthesis|chitin formation|beta-1,4-linked N-acetylglucosamine biosynthetic process|chitin anabolism|beta-1,4-linked N-acetylglucosamine biosynthesis|chitin synthesis													biological_process											owl:Class	
GO:0062204	biolink:NamedThing	(13S)-vitexifolin A synthase activity	Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate.	got7fsn_ti							dph	2020-01-03T13:24:50Z				RHEA:40027		molecular_function											owl:Class	
GO:0047370	biolink:NamedThing	succinate-citramalate CoA-transferase activity	Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate.	got7fsn_ti	succinyl coenzyme A-citramalyl coenzyme A transferase activity|succinyl-CoA:citramalate CoA-transferase activity|citramalate coenzyme A-transferase activity|itaconate CoA-transferase activity											MetaCyc:2.8.3.7-RXN|RHEA:23528		molecular_function											owl:Class	
GO:0032610	biolink:NamedThing	interleukin-1 alpha production	The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	interleukin-1 alpha biosynthetic process|IL-1 alpha production|interleukin-1 alpha secretion										GO:0050703|GO:0050719			biological_process											owl:Class	
GO:0060764	biolink:NamedThing	cell-cell signaling involved in mammary gland development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.	got7fsn_ti	cell-cell signalling involved in mammary gland development						dph	2009-07-06T09:24:53Z						biological_process											owl:Class	
GO:0031537	biolink:NamedThing	regulation of anthocyanin metabolic process	Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.	got7fsn_ti	regulation of anthocyanin metabolism													biological_process											owl:Class	
GO:1990402	biolink:NamedThing	embryonic liver development	The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.	got7fsn_ti							sl	2014-06-23T20:52:03Z						biological_process											owl:Class	
GO:0047543	biolink:NamedThing	2-hexadecenal reductase activity	Catalysis of the reaction: NADP(+) + palmitaldehyde = trans-hexadec-2-enal + H(+) + NADPH.	got7fsn_ti	hexadecanal:NADP+ delta2-oxidoreductase activity|hexadecanal: NADP+ oxidoreductase activity											EC:1.3.1.27|KEGG_REACTION:R02463|MetaCyc:2-HEXADECENAL-REDUCTASE-RXN|RHEA:12444		molecular_function											owl:Class	
GO:0046173	biolink:NamedThing	polyol biosynthetic process	The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.	got7fsn_ti	polyhydric alcohol biosynthetic process|polyol synthesis|polyol anabolism|polyol formation|polyol biosynthesis													biological_process											owl:Class	
GO:0031643	biolink:NamedThing	positive regulation of myelination	Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.	got7fsn_ti	up-regulation of myelination|stimulation of myelination|upregulation of myelination|up regulation of myelination|activation of myelination													biological_process											owl:Class	
GO:0102691	biolink:NamedThing	UDP-glucose:benzyladenine 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + benzyladenine-7-N-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-4729		molecular_function											owl:Class	
GO:0098848	biolink:NamedThing	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity	Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane.	got7fsn_ti	alpha-D-ribose-1-methylphosphonate-5-phosphate C-P-lyase (methane forming)											RHEA:34707|EC:4.7.1.1		molecular_function											owl:Class	
GO:0019917	biolink:NamedThing	peptidyl-D-alanine racemization via peptidyl-L-serine	The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine.	got7fsn_ti												RESID:AA0191		biological_process											owl:Class	
GO:0019399	biolink:NamedThing	cyclohexanol oxidation	The cyclohexanol metabolic process in which cyclohexanol is converted to adipate.	got7fsn_ti												MetaCyc:CYCLOHEXANOL-OXIDATION-PWY		biological_process											owl:Class	
GO:0050231	biolink:NamedThing	putrescine carbamoyltransferase activity	Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate.	got7fsn_ti	carbamoyl-phosphate:putrescine carbamoyltransferase activity|putrescine synthase activity|putrescine transcarbamylase activity|PTCase activity											MetaCyc:PUTRESCINE-CARBAMOYLTRANSFERASE-RXN|RHEA:21936|EC:2.1.3.6|KEGG_REACTION:R01399		molecular_function											owl:Class	
GO:0052806	biolink:NamedThing	sulfite reductase (coenzyme F420) activity	Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.	got7fsn_ti	hydrogen-sulfide:coenzyme F420 oxidoreductase activity|coenzyme F420-sulfite reductase activity|coenzyme F420-dependent sulfite reductase activity|sulfite:reduced coenzyme F420 reductase activity						ai	2011-09-22T04:08:13Z						molecular_function											owl:Class	
GO:0047544	biolink:NamedThing	2-hydroxybiphenyl 3-monooxygenase activity	Catalysis of the reaction: biphenyl-2-ol + H(+) + NADH + O(2) = biphenyl-2,3-diol + H(2)O + NAD(+).	got7fsn_ti	2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating)											RHEA:11996|KEGG_REACTION:R03964|MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN|UM-BBD_reactionID:r1423|EC:1.14.13.44		molecular_function											owl:Class	
GO:0034895	biolink:NamedThing	pyridine-3,4-diol dioxygenase activity	Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate.	got7fsn_ti												EC:1.13.11.-|UM-BBD_reactionID:r1398		molecular_function											owl:Class	
GO:0051169	biolink:NamedThing	nuclear transport	The directed movement of substances into, out of, or within the nucleus.	got7fsn_ti	nucleus transport											Wikipedia:Nuclear_transport		biological_process											owl:Class	
GO:0043392	biolink:NamedThing	negative regulation of DNA binding	Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).	got7fsn_ti	down-regulation of DNA binding|downregulation of DNA binding|inhibition of DNA binding|down regulation of DNA binding													biological_process											owl:Class	
GO:0033905	biolink:NamedThing	xylan endo-1,3-beta-xylosidase activity	Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans.	got7fsn_ti	1,3-beta-xylanase activity|endo-1,3-beta-xylanase activity|1,3-beta-D-xylan xylanohydrolase activity|endo-1,3-xylanase activity|xylanase activity|beta-1,3-xylanase activity|endo-beta-1,3-xylanase activity|1,3-xylanase activity											MetaCyc:3.2.1.32-RXN|EC:3.2.1.32		molecular_function											owl:Class	
GO:0003833	biolink:NamedThing	beta-alanyl-dopamine synthase activity	Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine).	got7fsn_ti	N-beta-alanyl dopamine synthetase activity|NBAD transferase activity													molecular_function											owl:Class	
GO:0042444	biolink:NamedThing	phenylethylamine biosynthetic process	The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.	got7fsn_ti	phenylethylamine anabolism|phenylethylamine formation|phenylethylamine biosynthesis|phenylethylamine synthesis													biological_process											owl:Class	
GO:0047190	biolink:NamedThing	2-acylglycerophosphocholine O-acyltransferase activity	Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.	got7fsn_ti	acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity|2-acylglycerol-3-phosphorylcholine acyltransferase activity|2-acylglycerophosphocholine acyltransferase activity											MetaCyc:2.3.1.62-RXN|EC:2.3.1.62|RHEA:10332|KEGG_REACTION:R01319		molecular_function											owl:Class	
GO:0009120	biolink:NamedThing	deoxyribonucleoside metabolic process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	deoxyribonucleoside metabolism													biological_process											owl:Class	
GO:0047810	biolink:NamedThing	D-alanine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.	got7fsn_ti	D-aspartate transaminase activity|D-amino acid transaminase activity|D-alanine-D-glutamate transaminase activity|D-amino acid aminotransferase activity|D-alanine aminotransferase activity|D-aspartate aminotransferase activity|D-aspartic aminotransferase activity|D-alanine transaminase activity|D-amino-acid transaminase activity											EC:2.6.1.21|RHEA:15869|MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN		molecular_function											owl:Class	
GO:0034285	biolink:NamedThing	response to disaccharide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.	got7fsn_ti	response to disaccharide stimulus													biological_process											owl:Class	
GO:0036134	biolink:NamedThing	12-hydroxyheptadecatrienoic acid synthase activity	Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA).	got7fsn_ti	prostaglandin H2 degradation activity						bf	2012-03-05T11:17:34Z				RHEA:48644|Reactome:R-HSA-2161613		molecular_function											owl:Class	
GO:0045522	biolink:NamedThing	interleukin-26 receptor binding	Binding to an interleukin-26 receptor.	got7fsn_ti	IL-26|interleukin-26 receptor ligand													molecular_function											owl:Class	
GO:0008674	biolink:NamedThing	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity	Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate.	got7fsn_ti	2-keto-3-deoxy-6-phosphogalactonic aldolase activity|2-dehydro-3-deoxyphosphogalactonate aldolase activity|2-keto-3-deoxy-6-phosphogalactonic acid aldolase activity|2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity|2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)|phospho-2-keto-3-deoxygalactonate aldolase activity|(KDPGal)aldolase activity|2-oxo-3-deoxygalactonate 6-phosphate aldolase activity|6-phospho-2-dehydro-3-deoxygalactonate aldolase activity|6-phospho-2-keto-3-deoxygalactonate aldolase activity|phospho-2-keto-3-deoxygalactonic aldolase activity											KEGG_REACTION:R01064|EC:4.1.2.21|MetaCyc:DEHYDDEOXPHOSGALACT-ALDOL-RXN|RHEA:24464		molecular_function											owl:Class	
GO:0070682	biolink:NamedThing	proteasome regulatory particle assembly	The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.	got7fsn_ti	proteasome regulatory complex assembly						mah	2009-06-02T03:46:29Z						biological_process											owl:Class	
GO:0072357	biolink:NamedThing	PTW/PP1 phosphatase complex	A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.	got7fsn_ti							mah	2010-11-15T03:32:27Z						cellular_component											owl:Class	
GO:0034058	biolink:NamedThing	endosomal vesicle fusion	The homotypic fusion of endocytic vesicles to form or add to an early endosome.	got7fsn_ti	endosome vesicle fusion													biological_process											owl:Class	
GO:0097723	biolink:NamedThing	amoeboid sperm motility	Any process involved in the controlled movement of an amoeboid sperm cell.	got7fsn_ti	ameboid sperm motility|amoeboid sperm movement|ameboid sperm movement						pr	2016-09-01T12:02:19Z						biological_process											owl:Class	
GO:0070613	biolink:NamedThing	regulation of protein processing	Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.	got7fsn_ti	regulation of protein maturation by peptide bond cleavage						mah	2009-04-29T02:49:14Z			GO:0010953			biological_process											owl:Class	
GO:0070839	biolink:NamedThing	metal ion export	The directed movement of metal cations, out of a cell or organelle.	got7fsn_ti	divalent metal ion export						mah	2009-07-31T01:07:46Z						biological_process											owl:Class	
GO:0005827	biolink:NamedThing	polar microtubule	Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart.	got7fsn_ti	pole-to-pole microtubule													cellular_component											owl:Class	
GO:0016036	biolink:NamedThing	cellular response to phosphate starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0047968	biolink:NamedThing	glyoxylate dehydrogenase (acylating) activity	Catalysis of the reaction: CoA + glyoxylate + NADP(+) = H(+) + NADPH + oxalyl-CoA.	got7fsn_ti	glyoxylate:NADP+ oxidoreductase (CoA-oxalylating)											MetaCyc:GLYOXYLATE-DEHYDROGENASE-ACYLATING-RXN|KEGG_REACTION:R00468|RHEA:21024|EC:1.2.1.17		molecular_function											owl:Class	
GO:0070966	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, no-go decay	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.	got7fsn_ti	nuclear-transcribed mRNA breakdown, no-go decay|nuclear-transcribed mRNA degradation, no-go decay|nuclear-transcribed mRNA catabolism, no-go decay|no-go decay|no-go mRNA decay						mah	2009-10-01T02:36:22Z						biological_process											owl:Class	
GO:0106329	biolink:NamedThing	L-phenylalaine oxidase activity	Catalysis of the reaction: H2O + L-phenylalanine + O2 = 3-phenylpyruvate + H2O2 + NH4(+).	got7fsn_ti							hjd	2020-09-30T19:33:52Z				RHEA:61240		molecular_function											owl:Class	
GO:0000372	biolink:NamedThing	Group I intron splicing	The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).	got7fsn_ti	mRNA splicing				Note that Group I introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; tRNA and mRNA of bacteria and bacteriophage; rRNA of protists and fungi; and occasionally in mRNA of animal mitochondria (e.g. sea anemone).									biological_process											owl:Class	
GO:0039698	biolink:NamedThing	polyadenylation of viral mRNA by polymerase stuttering	Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail.	got7fsn_ti	polyA stuttering						bf	2013-10-28T14:54:07Z				VZ:1916		biological_process											owl:Class	
GO:0047050	biolink:NamedThing	(S)-2-hydroxy-fatty acid dehydrogenase activity	Catalysis of the reaction: (S)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH.	got7fsn_ti	dehydrogenase, L-2-hydroxy fatty acid|(S)-2-hydroxy-fatty-acid dehydrogenase activity|L-2-hydroxy fatty acid dehydrogenase activity|(S)-2-hydroxystearate:NAD+ oxidoreductase activity|2-hydroxy fatty acid oxidase											MetaCyc:1.1.1.99-RXN|RHEA:11384|EC:1.1.1.99|KEGG_REACTION:R03022		molecular_function											owl:Class	
GO:0004157	biolink:NamedThing	dihydropyrimidinase activity	Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.	got7fsn_ti	hydantoin peptidase activity|D-hydantoinase activity|5,6-dihydropyrimidine amidohydrolase activity|pyrimidine hydrase activity|hydantoinase activity|hydropyrimidine hydrase activity											MetaCyc:DIHYDROPYRIMIDINASE-RXN|EC:3.5.2.2|Reactome:R-HSA-73589|Reactome:R-HSA-73618|RHEA:16121		molecular_function											owl:Class	
GO:0140449	biolink:NamedThing	centromere-nuclear envelope anchor activity	The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.	got7fsn_ti	centromere-inner nuclear envelope anchor activity|nuclear envelope-centromere tether activity|centromere nuclear envelope anchor activity|nuclear envelope-centromere anchor activity|centromere-inner nuclear envelope tether activity|centromere nuclear envelope tether activity|chromosome, centromeric region-nuclear envelope anchor activity	https://github.com/geneontology/go-ontology/issues/19227					pg	2020-04-07T06:27:08Z						molecular_function											owl:Class	
GO:0031765	biolink:NamedThing	type 2 galanin receptor binding	Binding to a type 2 galanin receptor.	got7fsn_ti	type 2 galanin receptor ligand													molecular_function											owl:Class	
GO:0001154	biolink:NamedThing	TFIIIB-class transcription factor complex binding	Binding to a general RNA polymerase III transcription factor belonging to the TFIIB complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.	got7fsn_ti	TFIIIB-class transcription factor binding						krc	2011-01-27T04:53:50Z						molecular_function											owl:Class	
GO:0034900	biolink:NamedThing	3-(N-formyl)-formiminopyruvate hydrolase activity	Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate.	got7fsn_ti												EC:3.5.99.-|UM-BBD_reactionID:r1399		molecular_function											owl:Class	
GO:0047108	biolink:NamedThing	(R)-3-hydroxyacid-ester dehydrogenase activity	Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH.	got7fsn_ti	(R)-3-hydroxyacid ester dehydrogenase activity|3-oxo ester (R)-reductase activity|ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity				Note that this term was EC:1.2.1.55.							EC:1.1.1.279|KEGG_REACTION:R04105|MetaCyc:1.2.1.55-RXN|RHEA:24352		molecular_function											owl:Class	
GO:0055016	biolink:NamedThing	hypochord development	The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.	got7fsn_ti	subnotochordal rod development													biological_process											owl:Class	
GO:0070182	biolink:NamedThing	DNA polymerase binding	Binding to a DNA polymerase.	got7fsn_ti														molecular_function											owl:Class	
GO:1900968	biolink:NamedThing	regulation of sarcinapterin metabolic process	Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process.	got7fsn_ti	regulation of sarcinapterin metabolism						tt	2012-06-14T03:58:11Z						biological_process											owl:Class	
GO:0032251	biolink:NamedThing	positive regulation of adenosine transport	Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	up-regulation of adenosine transport|stimulation of adenosine transport|activation of adenosine transport|up regulation of adenosine transport|upregulation of adenosine transport													biological_process											owl:Class	
GO:0009822	biolink:NamedThing	alkaloid catabolic process	The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).	got7fsn_ti	alkaloid degradation|alkaloid breakdown|alkaloid catabolism													biological_process											owl:Class	
GO:0061676	biolink:NamedThing	importin-alpha family protein binding	Binding to a member of the importin-alpha family.	got7fsn_ti							dph	2015-01-10T18:25:22Z						molecular_function											owl:Class	
GO:0050241	biolink:NamedThing	pyrroline-2-carboxylate reductase activity	Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.	got7fsn_ti	L-proline:NAD(P)+ 2-oxidoreductase activity|delta1-pyrroline-2-carboxylate reductase activity											MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN|EC:1.5.1.1		molecular_function											owl:Class	
GO:0044272	biolink:NamedThing	sulfur compound biosynthetic process	The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.	got7fsn_ti	sulfur compound formation|sulfur compound biosynthesis|sulfur compound synthesis|sulfur biosynthetic process|sulfur compound anabolism|sulfur biosynthesis													biological_process											owl:Class	
GO:0046593	biolink:NamedThing	mandelonitrile lyase activity	Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde.	got7fsn_ti	D-oxynitrilase activity|(R)-oxynitrilase activity|mandelonitrile benzaldehyde-lyase activity|hydroxynitrile lyase activity|mandelonitrile benzaldehyde-lyase (cyanide-forming)|D-alpha-hydroxynitrile lyase activity											RHEA:18313|EC:4.1.2.10|MetaCyc:MANDELONITRILE-LYASE-RXN		molecular_function											owl:Class	
GO:0106231	biolink:NamedThing	protein-propionyllysine depropionylase activity	Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.	got7fsn_ti					This reaction is the removal of a propionyl group from a propionylated lysine residue of a protein or peptide.		hjd	2019-10-18T14:14:47Z				RHEA:23500		molecular_function											owl:Class	
GO:0044218	biolink:NamedThing	other organism cell membrane	The cell membrane of a secondary organism with which the first organism is interacting.	got7fsn_ti	other organism membrane|foreign membrane						jl	2009-11-12T02:37:44Z			GO:0044279			cellular_component											owl:Class	
GO:0047032	biolink:NamedThing	3-alpha-hydroxyglycyrrhetinate dehydrogenase activity	Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP(+) = 3-oxoglycyrrhetinate + H(+) + NADPH.	got7fsn_ti	3alpha-hydroxyglycyrrhetinate dehydrogenase activity|3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase activity											RHEA:20816|KEGG_REACTION:R04099|EC:1.1.1.230|MetaCyc:1.1.1.230-RXN		molecular_function											owl:Class	
GO:0036515	biolink:NamedThing	serotonergic neuron axon guidance	The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues.	got7fsn_ti	5-HT axon guidance|serotonergic axon guidance						bf	2015-12-17T11:15:54Z						biological_process											owl:Class	
GO:0045294	biolink:NamedThing	alpha-catenin binding	Binding to catenin complex alpha subunit.	got7fsn_ti														molecular_function											owl:Class	
GO:0071060	biolink:NamedThing	alpha7-beta1 integrin-CD151 complex	A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151.	got7fsn_ti	ITGA7-ITGB1-CD151 complex						mah	2009-11-03T04:02:01Z						cellular_component											owl:Class	
GO:0140107	biolink:NamedThing	high-affinity potassium ion transmembrane transporter activity	Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti							pg	2017-10-12T09:54:39Z						molecular_function											owl:Class	
GO:0052599	biolink:NamedThing	methylputrescine oxidase activity	Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+.	got7fsn_ti	N-methylputrescine:oxygen oxidoreductase (deaminating) activity											EC:1.4.3.22|KEGG_REACTION:R05334|MetaCyc:RXN-8244		molecular_function											owl:Class	
GO:0140033	biolink:NamedThing	acetylation-dependent protein binding	Binding to a protein upon acetylation of the target protein.	got7fsn_ti					This term should only be used when the binding is shown to require acetylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of acetylation. It may be that the acetylation causes a conformational change that allows binding of the protein to another region; this type of acetylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T15:35:43Z						molecular_function											owl:Class	
GO:0050246	biolink:NamedThing	questin monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + questin = demethylsulochrin + NADP(+).	got7fsn_ti	questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening)|questin oxygenase activity											MetaCyc:QUESTIN-MONOOXYGENASE-RXN|KEGG_REACTION:R02417|RHEA:10836|EC:1.14.13.43		molecular_function											owl:Class	
GO:0097304	biolink:NamedThing	lipoprotein biosynthetic process via signal peptide cleavage	The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex.	got7fsn_ti	lipoprotein biosynthesis (signal peptide cleavage)						pr	2012-05-15T01:05:17Z						biological_process											owl:Class	
GO:0005005	biolink:NamedThing	transmembrane-ephrin receptor activity	Combining with a transmembrane ephrin to initiate a change in cell activity.	got7fsn_ti	transmembrane-Eph receptor activity													molecular_function											owl:Class	
GO:0036200	biolink:NamedThing	3-ketosteroid 9-alpha-monooxygenase activity	Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O.	got7fsn_ti	3-ketosteroid 9alpha-hydroxylase activity|KshAB activity						bf	2012-04-20T02:09:47Z				EC:1.14.15.30|RHEA:32199|KEGG_REACTION:R09860		molecular_function											owl:Class	
GO:0042216	biolink:NamedThing	phenanthrene catabolic process	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon.	got7fsn_ti	phenanthrene catabolism|phenanthrene degradation|phenanthrene breakdown											UM-BBD_pathwayID:phe		biological_process											owl:Class	
GO:0102177	biolink:NamedThing	24-methylenelophenol methyl oxidase activity	Catalysis of the reaction: 24-methylenelophenol + O2 + NADH + H+ <=> 4alpha-hydroxymethyl-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O.	got7fsn_ti												RHEA:58872|MetaCyc:RXN-11930		molecular_function											owl:Class	
GO:0033987	biolink:NamedThing	2-hydroxyisoflavanone dehydratase activity	Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O.	got7fsn_ti	2,7,4'-trihydroxyisoflavanone hydro-lyase activity|2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming) activity											EC:4.2.1.105|MetaCyc:RXN-3284|RHEA:16445		molecular_function											owl:Class	
GO:0035387	biolink:NamedThing	negative regulation of Roundabout signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.	got7fsn_ti	negative regulation of Roundabout signalling pathway						bf	2010-03-18T02:40:00Z						biological_process											owl:Class	
GO:0061624	biolink:NamedThing	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate	The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.	got7fsn_ti							dph	2014-04-29T12:58:28Z						biological_process											owl:Class	
GO:0051520	biolink:NamedThing	termination of bipolar cell growth	Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0051517	biolink:NamedThing	negative regulation of bipolar cell growth	Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.	got7fsn_ti	down-regulation of bipolar cell growth|downregulation of bipolar cell growth|inhibition of bipolar cell growth|down regulation of bipolar cell growth													biological_process											owl:Class	
GO:0102991	biolink:NamedThing	myristoyl-CoA hydrolase activity	Catalysis of the reaction: myristoyl-CoA + H2O <=> H+ + tetradecanoate + coenzyme A.	got7fsn_ti												RHEA:40119|EC:3.1.2.2|MetaCyc:RXN-9626		molecular_function											owl:Class	
GO:0031818	biolink:NamedThing	P2Y9 nucleotide receptor binding	Binding to a P2Y9 nucleotide receptor.	got7fsn_ti	P2Y9 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0031591	biolink:NamedThing	wybutosine biosynthetic process	The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.	got7fsn_ti	yW biosynthesis|yW biosynthetic process				Note that wybutosine is a hypermodified G-residue, formerly called the Y-base, and its derivatives are exclusively found at position 37 (anticodon loop) of tRNAPhe.									biological_process											owl:Class	
GO:0031627	biolink:NamedThing	telomeric loop formation	The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.	got7fsn_ti	t-loop biosynthesis|T loop biosynthesis|T loop formation|t-loop formation													biological_process											owl:Class	
GO:0052787	biolink:NamedThing	alpha-linked polysaccharide catabolism to maltopentaose	The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose.	got7fsn_ti	maltopentaose-forming alpha-amylase activity|alpha-amylase-mediated polysaccharide catabolism, producing maltopentaose						ai	2011-10-04T10:06:44Z						biological_process											owl:Class	
GO:0102993	biolink:NamedThing	linolenate delta15 desaturase activity	Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid alpha-linolenoyl group + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-9667|RHEA:46408		molecular_function											owl:Class	
GO:0071679	biolink:NamedThing	commissural neuron axon guidance	The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.	got7fsn_ti	commissural neuron axon pathfinding						mah	2010-02-17T02:21:36Z						biological_process											owl:Class	
GO:0047948	biolink:NamedThing	glutarate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H(+) + phosphate.	got7fsn_ti	glutaryl coenzyme A synthetase activity|glutaryl-CoA synthetase activity|glutarate:CoA ligase (ADP-forming)											RHEA:14169|MetaCyc:GLUTARATE--COA-LIGASE-RXN|EC:6.2.1.6|KEGG_REACTION:R02402		molecular_function											owl:Class	
GO:0034731	biolink:NamedThing	Lsm-containing SMN-Sm protein complex	An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA.	got7fsn_ti	SMN-containing protein complex													cellular_component											owl:Class	
GO:0102324	biolink:NamedThing	2-hydroxy-6-oxo-nona-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-nona-2,4-dienoate + H2O = butyrate + 2-oxopent-4-enoate + H+.	got7fsn_ti												MetaCyc:RXN-13157		molecular_function											owl:Class	
GO:0120327	biolink:NamedThing	telopode	A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21973					krc	2021-08-16T16:45:21Z						cellular_component											owl:Class	
GO:0036184	biolink:NamedThing	asperthecin biosynthetic process	The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.	got7fsn_ti	asperthecin synthesis|asperthecin biosynthesis|asperthecin formation						bf	2012-04-16T11:36:56Z						biological_process											owl:Class	
GO:0035368	biolink:NamedThing	selenocysteine insertion sequence binding	Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.	got7fsn_ti	SECIS binding						bf	2010-03-11T10:42:28Z						molecular_function											owl:Class	
GO:0140439	biolink:NamedThing	protein-cysteine S-stearoyltransferase activity	Catalysis of the transfer of a stearoyl (systematic name, octadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: octadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-octadecanoyl-L-cysteinyl-[protein].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18882					pg	2020-03-11T09:55:48Z				RHEA:59740		molecular_function											owl:Class	
GO:0043754	biolink:NamedThing	dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity	Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine.	got7fsn_ti	2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity|enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity|dihydrolipoyl transacylase activity|2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity											MetaCyc:2.3.1.168-RXN|RHEA:18865|EC:2.3.1.168		molecular_function											owl:Class	
GO:0099621	biolink:NamedThing	undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity	Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate.	got7fsn_ti	Ara4FN transferase activity|undecaprenyl phosphate-L-Ara4FN transferase activity|undecaprenyl-phosphate Ara4FN transferase activity										GO:0103019	MetaCyc:RXN0-3521|EC:2.4.2.53|RHEA:27722		molecular_function											owl:Class	
GO:0035460	biolink:NamedThing	L-ascorbate 6-phosphate lactonase activity	Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate.	got7fsn_ti							bf	2010-04-16T02:05:41Z				RHEA:28803		molecular_function											owl:Class	
GO:0019074	biolink:NamedThing	viral RNA genome packaging	The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid.	got7fsn_ti														biological_process											owl:Class	
GO:0002178	biolink:NamedThing	palmitoyltransferase complex	A protein complex with palmitoyltransferase activity.	got7fsn_ti							hjd	2010-12-03T10:49:17Z						cellular_component											owl:Class	
GO:0036073	biolink:NamedThing	perichondral ossification	Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage.	got7fsn_ti							bf	2011-12-19T01:49:38Z						biological_process											owl:Class	
GO:0071434	biolink:NamedThing	cell chemotaxis to angiotensin	The directed movement of a motile cell in response to the presence of angiotensin.	got7fsn_ti	angiotensin mediated chemotaxis|angiotensin-mediated cell chemotaxis						mah	2009-12-16T11:07:15Z						biological_process											owl:Class	
GO:0048246	biolink:NamedThing	macrophage chemotaxis	The movement of a macrophage in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0047278	biolink:NamedThing	bilirubin-glucuronoside glucuronosyltransferase activity	Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.	got7fsn_ti	bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase activity|bilirubin monoglucuronide transglucuronidase activity|bilirubin glucuronoside glucuronosyltransferase activity											KEGG_REACTION:R00062|RHEA:16885|MetaCyc:2.4.1.95-RXN		molecular_function											owl:Class	
GO:1900599	biolink:NamedThing	demethylkotanin biosynthetic process	The chemical reactions and pathways resulting in the formation of demethylkotanin.	got7fsn_ti	demethylkotanin anabolism|demethylkotanin formation|demethylkotanin biosynthesis|demethylkotanin synthesis						di	2012-05-15T06:55:21Z						biological_process											owl:Class	
GO:0097046	biolink:NamedThing	replication fork progression beyond termination site	Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks.	got7fsn_ti							pr	2011-05-03T03:34:01Z						biological_process											owl:Class	
GO:0010844	biolink:NamedThing	recombination hotspot binding	Binding to a genomic region which promotes recombination.	got7fsn_ti	DNA binding, recombination hotspot													molecular_function											owl:Class	
GO:1990594	biolink:NamedThing	L-altrarate dehydratase activity	Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.	got7fsn_ti	L-talarate dehydratase activity						jl	2014-12-16T14:23:55Z				RHEA:44028		molecular_function											owl:Class	
GO:0102542	biolink:NamedThing	aclacinomycin A methylesterase activity	Catalysis of the reaction: aclacinomycin A + H2O <=> 15-demethoxy-aclacinomycin A + methanol + H+.	got7fsn_ti												EC:3.1.1.95|MetaCyc:RXN-14863		molecular_function											owl:Class	
GO:0033429	biolink:NamedThing	CGU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CGU codon.	got7fsn_ti	CGT codon-amino acid adaptor activity|arginine tRNA				Note that in the standard genetic code, CGT codes for arginine.									molecular_function											owl:Class	
GO:1905170	biolink:NamedThing	negative regulation of protein localization to phagocytic vesicle	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle.	got7fsn_ti	inhibition of protein recruitment to phagosome|negative regulation of protein localization in phagocytic vesicle|down regulation of protein localization to phagocytic vesicle|down-regulation of protein localisation to phagosome|down regulation of protein localisation to phagocytic vesicle|negative regulation of protein recruitment to phagosome|negative regulation of protein localisation to phagosome|down-regulation of protein recruitment to phagosome|inhibition of protein localisation to phagocytic vesicle|downregulation of protein recruitment to phagosome|down regulation of protein recruitment to phagosome|inhibition of protein localization in phagocytic vesicle|downregulation of protein localisation to phagocytic vesicle|downregulation of protein localization in phagocytic vesicle|inhibition of protein localisation in phagocytic vesicle|inhibition of protein localisation to phagosome|down-regulation of protein localisation in phagocytic vesicle|downregulation of protein localization to phagocytic vesicle|down regulation of protein localization in phagocytic vesicle|down-regulation of protein localization to phagocytic vesicle|down-regulation of protein localization in phagocytic vesicle|down regulation of protein localisation to phagosome|negative regulation of protein localisation in phagocytic vesicle|down regulation of protein localisation in phagocytic vesicle|negative regulation of protein localisation to phagocytic vesicle|downregulation of protein localisation in phagocytic vesicle|inhibition of protein localization to phagocytic vesicle|downregulation of protein localisation to phagosome|down-regulation of protein localisation to phagocytic vesicle						bf	2016-05-02T18:38:22Z						biological_process											owl:Class	
GO:0060834	biolink:NamedThing	oral/aboral axis specification	The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo.	got7fsn_ti	oral/aboral axis determination						dph	2009-08-11T03:25:26Z						biological_process											owl:Class	
GO:0031934	biolink:NamedThing	mating-type region heterochromatin	Heterochromatic regions of the chromosome found at silenced mating-type loci.	got7fsn_ti														cellular_component											owl:Class	
GO:0034541	biolink:NamedThing	dimethylarsinite methyltransferase activity	Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH.	got7fsn_ti												UM-BBD_reactionID:r0806		molecular_function											owl:Class	
GO:0071575	biolink:NamedThing	integral component of external side of plasma membrane	The component of the plasma membrane consisting of the gene products that penetrate only the external side of the membrane.	got7fsn_ti	integral to external side of plasma membrane|integral to external leaflet of plasma membrane						mah	2010-01-26T05:20:28Z						cellular_component											owl:Class	
GO:0102750	biolink:NamedThing	tetrahydrogeranylgeranyl-chlorophyll a reductase activity	Catalysis of the reaction: chlorophyll a + NADP = tetrahydrogeranylgeranyl-chlorophyll a + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-7666		molecular_function											owl:Class	
GO:0001899	biolink:NamedThing	negative regulation of cytolysis by symbiont of host cells	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by symbiont of cytolysis of host cells|down regulation by symbiont of cytolysis of host cells|inhibition by symbiont of cytolysis of host cells|down-regulation by symbiont of cytolysis of host cells|downregulation by symbiont of cytolysis of host cells													biological_process											owl:Class	
GO:0042360	biolink:NamedThing	vitamin E metabolic process	The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.	got7fsn_ti	tocopherol metabolism|alpha-tocopherol metabolic process|vitamin E metabolism|tocopherol metabolic process|alpha-tocopherol metabolism													biological_process											owl:Class	
GO:1901593	biolink:NamedThing	response to GW 7647	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.	got7fsn_ti							mah	2012-11-07T17:16:48Z						biological_process											owl:Class	
GO:0047877	biolink:NamedThing	ephedrine dehydrogenase activity	Catalysis of the reaction: (1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH.	got7fsn_ti	(-)-ephedrine:NAD+ 2-oxidoreductase activity											EC:1.5.1.18|MetaCyc:EPHEDRINE-DEHYDROGENASE-RXN|KEGG_REACTION:R03614|RHEA:16289		molecular_function											owl:Class	
GO:0050209	biolink:NamedThing	polyvinyl-alcohol oxidase activity	Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2.	got7fsn_ti	polyvinyl-alcohol:oxygen oxidoreductase activity|PVA oxidase activity|dehydrogenase, polyvinyl alcohol											RHEA:21688|EC:1.1.3.30|MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN		molecular_function											owl:Class	
GO:0061761	biolink:NamedThing	alpha-latrotoxin receptor binding	Binding to an alpha-latrotoxin receptor.	got7fsn_ti	latrophilin binding|lasso receptor binding						dph	2016-04-13T10:46:42Z						molecular_function											owl:Class	
GO:0045173	biolink:NamedThing	O-sialoglycoprotein catabolic process	The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.	got7fsn_ti	O-sialoglycoprotein catabolism|O-sialoglycoprotein breakdown|O-sialoglycoprotein degradation													biological_process											owl:Class	
GO:0052766	biolink:NamedThing	mannoside alpha-1,4-mannosidase activity	Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.	got7fsn_ti	mannoside exo-alpha-1,4-mannosidase activity|alpha-1,4-exomannosidase activity|alpha-1,4-mannosidase activity|mannoside alpha-1,4-exomannosidase activity						ai	2011-09-30T12:55:24Z						molecular_function											owl:Class	
GO:0004910	biolink:NamedThing	interleukin-1, type II, blocking receptor activity	Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors.	got7fsn_ti	interleukin-1 blocking receptor activity|IL-1 type II, blocking binding|interleukin-1, type II, blocking binding|IL-1 type II, blocking receptor|interleukin-1 type II receptor activity										GO:0019968			molecular_function											owl:Class	
GO:0102869	biolink:NamedThing	6-hydroxyflavone-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 6-hydroxyflavone <=> 6-O-beta-D-glucosyl-6-hydroxyflavone + UDP + H+.	got7fsn_ti												MetaCyc:RXN-8354		molecular_function											owl:Class	
GO:0103064	biolink:NamedThing	inositol phosphorylceramide mannosyltransferase activity	Catalysis of the reaction: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1,6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H+.	got7fsn_ti												MetaCyc:RXN3O-663|EC:2.4.1.370|RHEA:64596|https://github.com/geneontology/go-ontology/issues/21803		molecular_function											owl:Class	
GO:0061591	biolink:NamedThing	calcium activated galactosylceramide scrambling	The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.	got7fsn_ti							dph	2014-02-05T15:25:52Z						biological_process											owl:Class	
GO:0007014	biolink:NamedThing	actin ubiquitination	The modification of actin by addition of ubiquitin groups.	got7fsn_ti	indirect flight muscle actin ubiquitination													biological_process											owl:Class	
GO:0047699	biolink:NamedThing	beta-diketone hydrolase activity	Catalysis of the reaction: H(2)O + nonane-4,6-dione = butanoate + H(+) + pentan-2-one.	got7fsn_ti	b-diketone hydrolase activity|oxidized PVA hydrolase activity|nonane-4,6-dione acylhydrolase activity											EC:3.7.1.7|KEGG_REACTION:R03781|MetaCyc:BETA-DIKETONE-HYDROLASE-RXN|RHEA:11908		molecular_function											owl:Class	
GO:1990224	biolink:NamedThing	NMN phosphatase activity	Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate.	got7fsn_ti	nicotinamide mononucleotide phosphatase activity|beta-nicotinamide D-ribonucleotide phosphatase activity						rb	2013-10-21T18:03:41Z				RHEA:30815		molecular_function											owl:Class	
GO:0006555	biolink:NamedThing	methionine metabolic process	The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.	got7fsn_ti	methionine and threonine metabolic process|methionine and threonine metabolism|methionine metabolism											UM-BBD_pathwayID:met		biological_process											owl:Class	
GO:0043876	biolink:NamedThing	D-threonine aldolase activity	Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde.	got7fsn_ti	low-specificity D-threonine aldolase|D-allo-TA|D-allo-threonine aldolase activity|D-TA|DtaAS											MetaCyc:4.1.2.42-RXN|EC:4.1.2.42|RHEA:15257		molecular_function											owl:Class	
GO:0043530	biolink:NamedThing	adenosine 5'-monophosphoramidase activity	Catalysis of the reaction: adenosine 5'-monophosphoramidate + H2O = AMP + NH4+. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester.	got7fsn_ti	adenosine 5'-monophosphoramidate hydrolase activity|adenosine 5' monophosphoramidase activity													molecular_function											owl:Class	
GO:0061703	biolink:NamedThing	pyroptosome complex	A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis.	got7fsn_ti	ASC pyroptosome						dph	2015-05-08T14:43:37Z						cellular_component											owl:Class	
GO:0022009	biolink:NamedThing	central nervous system vasculogenesis	The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21480												biological_process											owl:Class	
GO:0071181	biolink:NamedThing	MAML3-RBP-Jkappa-ICN3 complex	A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	got7fsn_ti	MAML3-RBP-Jkappa-Notch3 complex						mah	2009-11-23T02:52:05Z						cellular_component											owl:Class	
GO:1990085	biolink:NamedThing	Hda-beta clamp complex	A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda.	got7fsn_ti	Hda-DnaN complex|Hda-dpo3b complex						bhm	2013-04-30T11:53:18Z						cellular_component											owl:Class	
GO:0005872	biolink:NamedThing	minus-end kinesin complex	Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule.	got7fsn_ti														cellular_component											owl:Class	
GO:0019658	biolink:NamedThing	glucose fermentation to lactate and acetate	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP.	got7fsn_ti	bifidum pathway|glucose catabolic process to lactate and acetate											MetaCyc:P124-PWY		biological_process											owl:Class	
GO:0050468	biolink:NamedThing	reticuline oxidase activity	Catalysis of the reaction: (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2) + H(+).	got7fsn_ti	berberine-bridge-forming enzyme activity|(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming)|BBE|tetrahydroprotoberberine synthase activity|berberine bridge enzyme activity											EC:1.21.3.3|MetaCyc:RETICULINE-OXIDASE-RXN|KEGG_REACTION:R03831|RHEA:19885		molecular_function											owl:Class	
GO:0030907	biolink:NamedThing	MBF transcription complex	A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p.	got7fsn_ti	MBF|Mlu1-box binding factor|DSC1 transcription factor complex													cellular_component											owl:Class	
GO:0061675	biolink:NamedThing	RBL family protein binding	Binding to a member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.	got7fsn_ti	rhamnose-binding lectin family protein binding						dph	2015-01-10T18:22:42Z						molecular_function											owl:Class	
GO:0006590	biolink:NamedThing	thyroid hormone generation	The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.	got7fsn_ti					Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because thyroid hormones can only be formed by the proteolysis of a larger molecule (see term definition). The word 'generation' is therefore used in place of biosynthesis.									biological_process											owl:Class	
GO:0070488	biolink:NamedThing	neutrophil aggregation	The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.	got7fsn_ti	neutrophil leukocyte aggregation|neutrophil leucocyte aggregation|neutrocyte aggregation|neutrophilic leucocyte aggregation|neutrophilic leukocyte aggregation													biological_process											owl:Class	
GO:0090500	biolink:NamedThing	endocardial cushion to mesenchymal transition	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti							tb	2012-10-22T11:51:44Z						biological_process											owl:Class	
GO:0090588	biolink:NamedThing	protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in).	got7fsn_ti							tb	2014-06-04T16:22:31Z						molecular_function											owl:Class	
GO:0031752	biolink:NamedThing	D5 dopamine receptor binding	Binding to a D5 dopamine receptor.	got7fsn_ti	D1B dopamine receptor binding|D5 dopamine receptor ligand													molecular_function											owl:Class	
GO:0097500	biolink:NamedThing	receptor localization to non-motile cilium	A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium.	got7fsn_ti	receptor localization to nonmotile primary cilium						pr	2013-08-13T12:17:34Z						biological_process											owl:Class	
GO:0034851	biolink:NamedThing	2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA.	got7fsn_ti												UM-BBD_reactionID:r1274		molecular_function											owl:Class	
GO:0022886	biolink:NamedThing	channel-forming ionophore activity	Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.	got7fsn_ti	ionophore activity													molecular_function											owl:Class	
GO:0046736	biolink:NamedThing	induction of humoral immune response in host by virus	The intentional, virally-encoded stimulation of a host humoral defense response to viral infection.	got7fsn_ti	active viral induction of humoral immune response in host|active induction of humoral immune response in host by virus													biological_process											owl:Class	
GO:0060082	biolink:NamedThing	eye blink reflex	The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.	got7fsn_ti	nictitating membrane reflex													biological_process											owl:Class	
GO:0047056	biolink:NamedThing	(S)-canadine synthase activity	Catalysis of the reaction: (S)-tetrahydrocolumbamine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-canadine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	got7fsn_ti	(S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming) activity|(S)-tetrahydroberberine synthase activity	https://github.com/geneontology/go-ontology/issues/21133										RHEA:21456|EC:1.14.19.68|MetaCyc:1.1.3.36-RXN|KEGG_REACTION:R04400		molecular_function											owl:Class	
GO:0033951	biolink:NamedThing	oligosaccharide reducing-end xylanase activity	Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.	got7fsn_ti	Rex|reducing end xylose-releasing exo-oligoxylanase activity|beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranose reducing-end xylanase activity											MetaCyc:3.2.1.156-RXN|EC:3.2.1.156		molecular_function											owl:Class	
GO:0043000	biolink:NamedThing	Golgi to plasma membrane CFTR protein transport	The directed movement of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.	got7fsn_ti	Golgi to plasma membrane cystic fibrosis transmembrane conductance regulator protein transport													biological_process											owl:Class	
GO:0043001	biolink:NamedThing	Golgi to plasma membrane protein transport	The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0050251	biolink:NamedThing	retinol isomerase activity	Catalysis of the reaction: all-trans-retinol = 11-cis-retinol.	got7fsn_ti	all-trans-retinol isomerase activity|all-trans-retinol 11-cis-trans-isomerase activity											Reactome:R-HSA-2465926|MetaCyc:RETINOL-ISOMERASE-RXN|RHEA:19141|KEGG_REACTION:R02369		molecular_function											owl:Class	
GO:1900800	biolink:NamedThing	cspyrone B1 metabolic process	The chemical reactions and pathways involving cspyrone B1.	got7fsn_ti	cspyrone B1 metabolism						di	2012-06-04T09:50:37Z						biological_process											owl:Class	
GO:0097162	biolink:NamedThing	MADS box domain binding	Binding to a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs.	got7fsn_ti							pr	2011-09-27T10:10:59Z						molecular_function											owl:Class	
GO:0102789	biolink:NamedThing	UDP-D-glucose:cyanidin 5-O-beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin = H+ + cyanidin 5-O-beta-D-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-8005		molecular_function											owl:Class	
GO:0062185	biolink:NamedThing	secalciferol 1-monooxygenase activity	Catalysis of the reaction:2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin].	got7fsn_ti							dph	2019-11-26T18:46:18Z				RHEA:49064		molecular_function											owl:Class	
GO:0106356	biolink:NamedThing	4-hydroxybenzoate 3-monooxygenase [NADPH] activity	Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP+.	got7fsn_ti							hjd	2021-02-02T05:51:57Z				RHEA:19477		molecular_function											owl:Class	
GO:0001965	biolink:NamedThing	G-protein alpha-subunit binding	Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.	got7fsn_ti	G-alpha protein subunit binding													molecular_function											owl:Class	
GO:0018669	biolink:NamedThing	3-hydroxybenzoate 6-monooxygenase activity	Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+).	got7fsn_ti	3-hydroxybenzoic acid-6-hydroxylase activity|3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)|m-hydroxybenzoate 6-hydroxylase activity|3-hydroxybenzoate 6-hydroxylase activity											RHEA:22692|KEGG_REACTION:R02589|EC:1.14.13.24|UM-BBD_reactionID:r0402|MetaCyc:3-HYDROXYBENZOATE-6-MONOOXYGENASE-RXN		molecular_function											owl:Class	
GO:0102289	biolink:NamedThing	beta-amyrin 11-oxidase activity	Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ <=> 11-oxo-beta-amyrin + 3 H2O + 2 NADP.	got7fsn_ti												EC:1.14.14.152|MetaCyc:RXN-12680|RHEA:31711		molecular_function											owl:Class	
GO:0047030	biolink:NamedThing	4-hydroxycyclohexanecarboxylate dehydrogenase activity	Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD(+) = 4-oxocyclohexanecarboxylate + H(+) + NADH.	got7fsn_ti	trans-4-hydroxycyclohexanecarboxylate dehydrogenase activity|trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase activity											KEGG_REACTION:R04307|EC:1.1.1.226|MetaCyc:1.1.1.226-RXN|RHEA:17429		molecular_function											owl:Class	
GO:0060307	biolink:NamedThing	regulation of ventricular cardiac muscle cell membrane repolarization	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.	got7fsn_ti	electrocardiogram T wave|regulation of ventricular cardiac muscle cell repolarization|regulation of ventricular cardiac muscle repolarization|ventricular repolarization|regulation of ventricular cardiomyocyte membrane repolarization													biological_process											owl:Class	
GO:0099623	biolink:NamedThing	regulation of cardiac muscle cell membrane repolarization	Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.	got7fsn_ti	regulation of cardiac muscle cell repolarization|heart repolarization|regulation of cardiomyocyte membrane repolarization													biological_process											owl:Class	
GO:0046025	biolink:NamedThing	precorrin-6Y C5,15-methyltransferase (decarboxylating) activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2.	got7fsn_ti	precorrin-6 methyltransferase activity|S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)|precorrin-6Y methylase activity											EC:2.1.1.132|RHEA:17477|MetaCyc:2.1.1.132-RXN		molecular_function											owl:Class	
GO:0052749	biolink:NamedThing	glucose-6-phosphate dehydrogenase (coenzyme F420) activity	Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420.	got7fsn_ti	coenzyme F420-dependent glucose-6-phosphate dehydrogenase activity|D-glucose-6-phosphate:F420 1-oxidoreductase activity|F420-dependent glucose-6-phosphate dehydrogenase activity						ai	2011-09-21T01:21:54Z				MetaCyc:RXN-11283|EC:1.1.98.2|KEGG_REACTION:R09550|RHEA:27294		molecular_function											owl:Class	
GO:0097424	biolink:NamedThing	nucleolus-associated heterochromatin	Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus.	got7fsn_ti							pr	2012-11-07T13:43:17Z				NIF_Subcellular:sao1210952635		cellular_component											owl:Class	
GO:0061743	biolink:NamedThing	motor learning	Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.	got7fsn_ti							dph	2015-11-09T12:40:29Z						biological_process											owl:Class	
GO:0140610	biolink:NamedThing	RNA sequestering activity	The selective interaction of a protein with a specific RNA molecule to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20945					pg	2021-02-24T13:53:46Z						molecular_function											owl:Class	
GO:0042819	biolink:NamedThing	vitamin B6 biosynthetic process	The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	got7fsn_ti	vitamin B6 biosynthesis|vitamin B6 anabolism|pyridoxine-5'-phosphate biosynthesis|vitamin B6 formation|vitamin B6 synthesis													biological_process											owl:Class	
GO:0018612	biolink:NamedThing	dibenzothiophene dioxygenase activity	Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene.	got7fsn_ti												EC:1.14.12.-|UM-BBD_reactionID:r0160		molecular_function											owl:Class	
GO:0102217	biolink:NamedThing	6-phosphoglucan, water dikinase activity	Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin.	got7fsn_ti												MetaCyc:RXN-12202|EC:2.7.9.5|RHEA:10256		molecular_function											owl:Class	
GO:0007505	biolink:NamedThing	adult fat body development	The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body.	got7fsn_ti														biological_process											owl:Class	
GO:0033983	biolink:NamedThing	diaminobutyrate decarboxylase activity	Catalysis of the reaction: L-2,4-diaminobutyrate + H(+) = 1,3-diaminopropane + CO(2).	got7fsn_ti	L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming) activity|L-2,4-diaminobutyrate decarboxylase activity|DABA DC|L-2,4-diaminobutanoate carboxy-lyase activity											MetaCyc:4.1.1.86-RXN|RHEA:15689|KEGG_REACTION:R07650|EC:4.1.1.86		molecular_function											owl:Class	
GO:0005112	biolink:NamedThing	Notch binding	Binding to a Notch (N) protein, a surface receptor.	got7fsn_ti	N ligand|Notch ligand|N binding|Notch receptor binding													molecular_function											owl:Class	
GO:0042004	biolink:NamedThing	feminization of hermaphrodite soma	Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans.	got7fsn_ti														biological_process											owl:Class	
GO:0072645	biolink:NamedThing	interferon-delta production	The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IFND production|IFN-delta production|interferon-delta secretion				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072646			biological_process											owl:Class	
GO:0034191	biolink:NamedThing	apolipoprotein A-I receptor binding	Binding to an apolipoprotein A-I receptor.	got7fsn_ti					Note that this term is to be used only to annotate gene products that bind to lipid-free APOA1. For receptors that bind lipid-associated apolipoproteins (plasma lipoprotein particles), consider annotating to 'lipoprotein receptor activity ; GO:0030228' or its child terms.									molecular_function											owl:Class	
GO:0061344	biolink:NamedThing	regulation of cell adhesion involved in heart morphogenesis	Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.	got7fsn_ti							dph	2010-09-29T11:35:27Z						biological_process											owl:Class	
GO:0009924	biolink:NamedThing	octadecanal decarbonylase activity	Catalysis of the reaction: octadecanal = heptadecane + CO.	got7fsn_ti	octadecanal alkane-lyase activity											RHEA:30415|EC:4.1.99.5|MetaCyc:OCTADECANAL-DECARBONYLASE-RXN		molecular_function											owl:Class	
GO:0097507	biolink:NamedThing	hypoxanthine DNA N-glycosylase activity	DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine).	got7fsn_ti	hypoxanthine-DNA glycosylase activity						pr	2013-09-26T16:02:08Z						molecular_function											owl:Class	
GO:0047669	biolink:NamedThing	amylosucrase activity	Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1).	got7fsn_ti	sucrose-1,4-alpha-glucan glucosyltransferase activity|sucrose-glucan glucosyltransferase activity|sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity											EC:2.4.1.4|RHEA:24572|MetaCyc:AMYLOSUCRASE-RXN		molecular_function											owl:Class	
GO:0080102	biolink:NamedThing	3-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate.	got7fsn_ti							dhl	2009-04-23T04:26:41Z				MetaCyc:RXN-2221		molecular_function											owl:Class	
GO:1901222	biolink:NamedThing	regulation of NIK/NF-kappaB signaling	Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling.	got7fsn_ti	regulation of NF-kappaB import into nucleus|NF-KB import into nucleus|NF-kappaB import into nucleus|regulation of NIK/NF-kappaB cascade|regulation of non-canonical NF-KB signaling|regulation of noncanonical NF-kappaB signaling|regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|regulation of p52-dependent NF-kappaB signaling						hjd	2012-08-06T20:27:17Z			GO:0042348|GO:0042345			biological_process											owl:Class	
GO:0071250	biolink:NamedThing	cellular response to nitrite	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.	got7fsn_ti							mah	2009-12-03T03:03:49Z						biological_process											owl:Class	
GO:1990418	biolink:NamedThing	response to insulin-like growth factor stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.	got7fsn_ti							sl	2014-07-14T22:47:59Z						biological_process											owl:Class	
GO:0102418	biolink:NamedThing	luteolin-7-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: luteolin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = luteolin-7-O-gentiobioside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-13801		molecular_function											owl:Class	
GO:0047898	biolink:NamedThing	formate dehydrogenase (cytochrome) activity	Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1.	got7fsn_ti	formate:cytochrome b1 oxidoreductase activity|formate:ferricytochrome-b1 oxidoreductase activity											EC:1.2.2.1|RHEA:21520|MetaCyc:FORMATE-DEHYDROGENASE-CYTOCHROME-RXN		molecular_function											owl:Class	
GO:0018585	biolink:NamedThing	fluorene oxygenase activity	Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.	got7fsn_ti												UM-BBD_reactionID:r0407		molecular_function											owl:Class	
GO:0102152	biolink:NamedThing	Delta12-linoleate epoxygenase activity	Catalysis of the reaction: H+ + 1-palmitoyl-2-linoleoyl-phosphatidylcholine + NADPH + O2 <=> 1-palmitoyl-2-vernoloyl-phosphatidylcholine + NADP + H2O.	got7fsn_ti												MetaCyc:RXN-11671		molecular_function											owl:Class	
GO:0045687	biolink:NamedThing	positive regulation of glial cell differentiation	Any process that activates or increases the frequency, rate or extent of glia cell differentiation.	got7fsn_ti	activation of glial cell differentiation|stimulation of glial cell differentiation|positive regulation of glia cell differentiation|up regulation of glial cell differentiation|positive regulation of neuroglia differentiation|up-regulation of glial cell differentiation|upregulation of glial cell differentiation													biological_process											owl:Class	
GO:0047489	biolink:NamedThing	pectate disaccharide-lyase activity	Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin.	got7fsn_ti	exopectic acid transeliminase activity|(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase activity|exo-PATE|Exo-PATE activity|exopectate lyase activity|PATE activity|Exo-PGL activity|exopolygalacturonic acid-trans-eliminase activity|exo-PGL|pectate exo-lyase activity|exopolygalacturonate lyase activity											MetaCyc:4.2.2.9-RXN|RHEA:57104|EC:4.2.2.9		molecular_function											owl:Class	
GO:0019423	biolink:NamedThing	sulfur oxidation, ferric ion-dependent	A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+).	got7fsn_ti	sulphur oxidation, ferric ion-dependent											MetaCyc:FESULFOX-PWY		biological_process											owl:Class	
GO:0047572	biolink:NamedThing	3-phosphoglycerate phosphatase activity	Catalysis of the reaction: 3-phospho-D-glycerate + H(2)O = D-glycerate + phosphate.	got7fsn_ti	D-3-phosphoglycerate phosphatase activity|3-PGA phosphatase activity|D-glycerate-3-phosphate phosphohydrolase activity											EC:3.1.3.38|RHEA:12412|KEGG_REACTION:R01511|MetaCyc:3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN		molecular_function											owl:Class	
GO:0140563	biolink:NamedThing	UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity	Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16869					pg	2020-11-25T16:07:58Z				RHEA:56064|EC:2.4.2.42		molecular_function											owl:Class	
GO:0098576	biolink:NamedThing	lumenal side of membrane	Any side (leaflet) of a membrane that faces the lumen of an organelle.	got7fsn_ti														cellular_component											owl:Class	
GO:0034816	biolink:NamedThing	anthracene 9,10-dioxygenase activity	Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol.	got7fsn_ti												UM-BBD_reactionID:r1141		molecular_function											owl:Class	
GO:0047585	biolink:NamedThing	4-pyridoxolactonase activity	Catalysis of the reaction: 4-pyridoxolactone + H(2)O = 4-pyridoxate + H(+).	got7fsn_ti	4-pyridoxolactone lactonohydrolase activity											MetaCyc:4-PYRIDOXOLACTONASE-RXN|EC:3.1.1.27|RHEA:14301|KEGG_REACTION:R02992		molecular_function											owl:Class	
GO:0042283	biolink:NamedThing	dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.	got7fsn_ti	dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase activity											RHEA:31307|EC:2.4.1.265|MetaCyc:RXN-5471		molecular_function											owl:Class	
GO:0016631	biolink:NamedThing	enoyl-[acyl-carrier-protein] reductase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+.	got7fsn_ti	enoyl-ACP reductase activity|acyl-ACP dehydrogenase activity|enoyl-[acyl-carrier protein] reductase activity|enoyl-acyl carrier protein reductase											MetaCyc:RXN1G-2527|MetaCyc:RXN1G-2544|MetaCyc:RXN1G-3667|MetaCyc:RXN1G-3232|Wikipedia:Enoyl-acyl_carrier_protein_reductase|MetaCyc:RXN1G-4140|MetaCyc:RXN1G-3613|MetaCyc:RXN1G-3993|MetaCyc:1.3.1.39-RXN|MetaCyc:RXN1G-45|MetaCyc:1.3.1.10-RXN|MetaCyc:RXN1G-3256|EC:1.3.1.9|MetaCyc:RXN1G-3641		molecular_function											owl:Class	
GO:0018765	biolink:NamedThing	2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity	Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate.	got7fsn_ti												RHEA:59220|MetaCyc:2-OH-6-OXOHEPTA-2-4-DIENOATE-HYDR-RXN|UM-BBD_reactionID:r0263		molecular_function											owl:Class	
GO:0045337	biolink:NamedThing	farnesyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.	got7fsn_ti	farnesyl diphosphate biosynthesis|farnesyl diphosphate synthesis|farnesyl diphosphate anabolism|farnesyl diphosphate formation											MetaCyc:PWY-5123		biological_process											owl:Class	
GO:0090430	biolink:NamedThing	caffeoyl-CoA: alcohol caffeoyl transferase activity	Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA.	got7fsn_ti							tb	2012-07-25T10:48:15Z						molecular_function											owl:Class	
GO:0140460	biolink:NamedThing	response to Gram-negative bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19278					pg	2020-04-30T07:34:38Z						biological_process											owl:Class	
GO:0047659	biolink:NamedThing	alpha-santonin 1,2-reductase activity	Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+.	got7fsn_ti	a-santonin 1,2-reductase activity|1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase activity											EC:1.3.1.47|MetaCyc:ALPHA-SANTONIN-12-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0034694	biolink:NamedThing	response to prostaglandin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.	got7fsn_ti	response to prostaglandin stimulus													biological_process											owl:Class	
GO:1903189	biolink:NamedThing	glyoxal metabolic process	The chemical reactions and pathways involving glyoxal.	got7fsn_ti	glyoxal metabolism						bf	2014-07-15T10:11:45Z						biological_process											owl:Class	
GO:0102912	biolink:NamedThing	(-)-lactol dehydrogenase activity	Catalysis of the reaction: (-)-lactol + NAD <=> H+ + (-)-matairesinol + NADH.	got7fsn_ti												MetaCyc:RXN-8681		molecular_function											owl:Class	
GO:0102168	biolink:NamedThing	5-methyl-phenazine-1-carboxylate N-methyltransferase activity	Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine  <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-11897|RHEA:49112		molecular_function											owl:Class	
GO:0018111	biolink:NamedThing	methionine racemase activity	Catalysis of the reaction: L-methionine = D-methionine.	got7fsn_ti												RHEA:12492|KEGG_REACTION:R00655|MetaCyc:METHIONINE-RACEMASE-RXN|EC:5.1.1.2		molecular_function											owl:Class	
GO:0050020	biolink:NamedThing	L-arabinonate dehydratase activity	Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O.	got7fsn_ti	L-arabinonate hydro-lyase activity|L-arabonate dehydrase activity|L-arabonate dehydratase activity|L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming)											EC:4.2.1.25|KEGG_REACTION:R02522|MetaCyc:L-ARABINONATE-DEHYDRATASE-RXN|RHEA:20968		molecular_function											owl:Class	
GO:0051506	biolink:NamedThing	ergosterol UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol.	got7fsn_ti												MetaCyc:RXN-16975)|RHEA:61836		molecular_function											owl:Class	
GO:0052694	biolink:NamedThing	jasmonoyl-isoleucine-12-hydroxylase activity	Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O.	got7fsn_ti												MetaCyc:RXN-12421|RHEA:54808		molecular_function											owl:Class	
GO:0018518	biolink:NamedThing	5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity	Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH.	got7fsn_ti	5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase activity|5,6-dihydrodiol-3-methyl-2-oxo-1,2-dihydroquinoline dehydrogenase											MetaCyc:RXN-643|UM-BBD_reactionID:r0053|EC:1.3.1.65|KEGG_REACTION:R05312|RHEA:24556		molecular_function											owl:Class	
GO:0003244	biolink:NamedThing	radial growth involved in right ventricle morphogenesis	The morphogenic growth in which the right ventricle grows along a radial axis.	got7fsn_ti							dph	2009-10-13T11:38:23Z						biological_process											owl:Class	
GO:0033054	biolink:NamedThing	D-glutamate metabolic process	The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid.	got7fsn_ti	D-glutamate metabolism													biological_process											owl:Class	
GO:0002548	biolink:NamedThing	monocyte chemotaxis	The movement of a monocyte in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0010878	biolink:NamedThing	cholesterol storage	The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti	cholesterol sequestration|sequestration of cholesterol													biological_process											owl:Class	
GO:0102793	biolink:NamedThing	soyasapogenol B glucuronosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B <=> H+ + UDP + soyasapogenol B 3-O-beta-glucuronate.	got7fsn_ti												RHEA:31475|MetaCyc:RXN-8086|EC:2.4.1.262		molecular_function											owl:Class	
GO:0042586	biolink:NamedThing	peptide deformylase activity	Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide.	got7fsn_ti	polypeptide deformylase activity|PDF activity|formyl-L-methionyl peptide amidohydrolase activity											MetaCyc:3.5.1.88-RXN|EC:3.5.1.88|RHEA:24420		molecular_function											owl:Class	
GO:0060250	biolink:NamedThing	germ-line stem-cell niche homeostasis	A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion.	got7fsn_ti	germ-line stem-cell niche maintenance|maintenance of germ line stem-cell niche|maintenance of germ line stem cell niche|maintenance of germ-line stem-cell niche|maintenance of germ-line stem cell niche													biological_process											owl:Class	
GO:0080013	biolink:NamedThing	(E,E)-geranyllinalool synthase activity	Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate.	got7fsn_ti												MetaCyc:RXN-10441|RHEA:38155		molecular_function											owl:Class	
GO:0004837	biolink:NamedThing	tyrosine decarboxylase activity	Catalysis of the reaction: L-tyrosine = tyramine + CO2.	got7fsn_ti	L-tyrosine decarboxylase activity|L-(-)-tyrosine apodecarboxylase activity|L-tyrosine carboxy-lyase activity|L-tyrosine carboxy-lyase (tyramine-forming)											RHEA:14345|MetaCyc:TYROSINE-DECARBOXYLASE-RXN|EC:4.1.1.25		molecular_function											owl:Class	
GO:0102575	biolink:NamedThing	3-oxo-dodecanoyl-ACP hydrolase activity	Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein].	got7fsn_ti												MetaCyc:RXN-15281		molecular_function											owl:Class	
GO:0030795	biolink:NamedThing	methyl jasmonate methylesterase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonate = S-adenosyl-L-homocysteine + a methyljasmonate.	got7fsn_ti	S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase activity|S-adenosyl-L-methionine:jasmonate O-methyltransferase activity|jasmonic acid carboxyl methyltransferase activity										GO:0102078|GO:0045546	EC:2.1.1.141|MetaCyc:RXN-10768|RHEA:13349		molecular_function											owl:Class	
GO:0003680	biolink:NamedThing	minor groove of adenine-thymine-rich DNA binding	Binding to a DNA structure formed by the minor groove of adenine-thymine-rich DNA regions. Examples of proteins having this function are AT-rich interaction domain (ARID)-containing proteins.	got7fsn_ti	AT binding|AT DNA binding|AT-rich DNA binding	https://github.com/geneontology/go-ontology/issues/19695												molecular_function											owl:Class	
GO:0047678	biolink:NamedThing	arginine 2-monooxygenase activity	Catalysis of the reaction: L-arginine + O(2) = 4-guanidinobutanamide + CO(2) + H(2)O.	got7fsn_ti	arginine oxygenase (decarboxylating) activity|L-arginine:oxygen 2-oxidoreductase (decarboxylating)|arginine decarboxy-oxidase activity|arginine monooxygenase activity											KEGG_REACTION:R00559|MetaCyc:ARGININE-2-MONOOXYGENASE-RXN|EC:1.13.12.1|RHEA:10548		molecular_function											owl:Class	
GO:0034847	biolink:NamedThing	naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity	Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-.	got7fsn_ti												UM-BBD_reactionID:r1260		molecular_function											owl:Class	
GO:0034677	biolink:NamedThing	integrin alpha7-beta1 complex	An integrin complex that comprises one alpha7 subunit and one beta1 subunit.	got7fsn_ti	ITGA7-ITGB1 complex|alpha7-beta1 integrin complex													cellular_component											owl:Class	
GO:0090638	biolink:NamedThing	phosphatidylcholine biosynthesis from phosphatidylethanolamine	The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations.	got7fsn_ti							tb	2015-04-23T15:56:12Z						biological_process											owl:Class	
GO:0019727	biolink:NamedThing	mevaldate reductase (NAD+) activity	Catalysis of the reaction: (R)-mevalonate + NAD(+) = H(+) + mevaldate + NADH.	got7fsn_ti												EC:1.1.1.32|KEGG_REACTION:R02246|RHEA:13221|MetaCyc:MEVALDATE-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0097279	biolink:NamedThing	histamine secretion mediated by IgE immunoglobulin	Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.	got7fsn_ti	histamine secretion mediated by IgE antibody|Ig-mediated histamine release						pr	2012-03-22T06:42:13Z						biological_process											owl:Class	
GO:0060813	biolink:NamedThing	anterior mRNA localization involved in anterior/posterior axis specification	Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.	got7fsn_ti	anterior mRNA localisation involved in anterior/posterior axis specification						dph	2009-08-07T09:51:47Z						biological_process											owl:Class	
GO:0061486	biolink:NamedThing	high-affinity fructose transmembrane transporter activity	Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	high affinity fructose transmembrane transporter activity						dph	2012-12-04T10:34:55Z						molecular_function											owl:Class	
GO:0120053	biolink:NamedThing	ribitol beta-1,4-xylosyltransferase activity	Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R.	got7fsn_ti							krc	2017-06-13T19:35:01Z						molecular_function											owl:Class	
GO:0072585	biolink:NamedThing	xanthosine nucleotidase activity	Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.	got7fsn_ti	xanthosine ribohydrolase activity						mah	2011-02-08T04:38:31Z				MetaCyc:RXN0-363|RHEA:27994		molecular_function											owl:Class	
GO:0046414	biolink:NamedThing	organomercury biosynthetic process	The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom.	got7fsn_ti	organomercury anabolism|organomercury biosynthesis|organomercury formation|organomercury synthesis													biological_process											owl:Class	
GO:0050280	biolink:NamedThing	sequoyitol dehydrogenase activity	Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH.	got7fsn_ti	5-O-methyl-myo-inositol:NAD+ oxidoreductase activity											KEGG_REACTION:R03497|MetaCyc:SEQUOYITOL-DEHYDROGENASE-RXN|RHEA:11300|EC:1.1.1.143		molecular_function											owl:Class	
GO:0086005	biolink:NamedThing	ventricular cardiac muscle cell action potential	An action potential that occurs in a ventricular cardiac muscle cell.	got7fsn_ti							tb	2011-11-10T07:59:36Z						biological_process											owl:Class	
GO:0005119	biolink:NamedThing	smoothened binding	Binding to a smoothened (smo) protein, which interacts with patched to transmit hedgehog signals.	got7fsn_ti	smo ligand|smo binding|smoothened ligand													molecular_function											owl:Class	
GO:0034535	biolink:NamedThing	1,2-dihydroxy-8-methylnaphthalene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+.	got7fsn_ti												UM-BBD_reactionID:r0781		molecular_function											owl:Class	
GO:0048941	biolink:NamedThing	posterior lateral line nerve glial cell development	The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0019101	biolink:NamedThing	female somatic sex determination	The determination of sex and sexual phenotypes in a female organism's soma.	got7fsn_ti														biological_process											owl:Class	
GO:0080131	biolink:NamedThing	hydroxyjasmonate sulfotransferase activity	Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate.	got7fsn_ti	hydroxyjasmonic acid sulfotransferase activity|OHJA sulfotransferase activity|12-hydroxyjasmonic acid sulfotransferase activity|12-hydroxyjasmonate sulfotransferase activity|12-OHJA sulfotransferase activity|11-hydroxyjasmonate sulfotransferase activity|11-hydroxyjasmonic acid sulfotransferase activity|11-OHJA sulfotransferase activity						dhl	2009-04-29T03:47:12Z						molecular_function											owl:Class	
GO:0052809	biolink:NamedThing	acharan sulfate lyase activity	Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid.	got7fsn_ti							ai	2011-09-26T02:58:28Z						molecular_function											owl:Class	
GO:0062188	biolink:NamedThing	anandamide 11,12 epoxidase activity	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti							dph	2019-11-26T18:53:52Z				RHEA:53144		molecular_function											owl:Class	
GO:0102712	biolink:NamedThing	gibberellin A13,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 <=> gibberellin A43 + succinate + carbon dioxide.	got7fsn_ti												MetaCyc:RXN-6542		molecular_function											owl:Class	
GO:0033728	biolink:NamedThing	divinyl chlorophyllide a 8-vinyl-reductase activity	Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+.	got7fsn_ti	[4-vinyl]chlorophyllide a reductase activity|4VCR|chlorophyllide-a:NADP+ oxidoreductase activity											RHEA:14449|MetaCyc:RXN-5286|EC:1.3.1.75		molecular_function											owl:Class	
GO:0120106	biolink:NamedThing	mitotic actomyosin contractile ring, distal actin filament layer	The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to.	got7fsn_ti	actomyosin contractile ring, distal actin filament layer						krc	2017-10-11T22:56:44Z						cellular_component											owl:Class	
GO:0047339	biolink:NamedThing	nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity	Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate.	got7fsn_ti	nucleoside diphosphohexose pyrophosphorylase activity|NDP-hexose diphosphorylase activity|NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity|hexose-1-phosphate guanylyltransferase activity|GTP:alpha-D-hexose-1-phosphate guanylyltransferase activity|hexose 1-phosphate nucleotidyltransferase activity|NDP hexose pyrophosphorylase activity|hexose 1-phosphate guanylyltransferase activity|NTP:hexose-1-phosphate nucleotidyltransferase activity|nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase activity|guanosine diphosphohexose pyrophosphorylase activity|GDP hexose pyrophosphorylase activity|hexose nucleotidylating enzyme activity|NDP-hexose pyrophosphorylase activity|GTP:hexose-1-phosphate guanylyltransferase activity										GO:0047340	MetaCyc:2.7.7.28-RXN|EC:2.7.7.28		molecular_function											owl:Class	
GO:0044296	biolink:NamedThing	dendritic tuft	The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance.	got7fsn_ti	dendrite tuft						jl	2010-02-04T04:03:29Z				NIF_Subcellular:sao1340260079		cellular_component											owl:Class	
GO:0047528	biolink:NamedThing	2,3-dihydroxyindole 2,3-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxyindole + O(2) = anthranilate + CO(2) + H(+).	got7fsn_ti	2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing) activity											RHEA:19445|KEGG_REACTION:R00983|MetaCyc:23-DIHYDROXYINDOLE-23-DIOXYGENASE-RXN|EC:1.13.11.23		molecular_function											owl:Class	
GO:0003989	biolink:NamedThing	acetyl-CoA carboxylase activity	Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.	got7fsn_ti	acetyl-CoA:carbon-dioxide ligase (ADP-forming)|acetyl coenzyme A carboxylase activity											EC:6.4.1.2|RHEA:11308|Reactome:R-HSA-75851|Reactome:R-HSA-8876889|Reactome:R-HSA-200555|MetaCyc:ACETYL-COA-CARBOXYLTRANSFER-RXN		molecular_function											owl:Class	
GO:0072099	biolink:NamedThing	anterior/posterior pattern specification involved in ureteric bud development	The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.	got7fsn_ti	ureteric bud anterior/posterior pattern formation						mah	2010-02-10T02:12:09Z						biological_process											owl:Class	
GO:0000140	biolink:NamedThing	acylglycerone-phosphate reductase activity	Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H(+).	got7fsn_ti	palmitoyl dihydroxyacetone phosphate reductase activity|palmitoyl-dihydroxyacetone-phosphate reductase activity|palmitoyldihydroxyacetone-phosphate reductase activity|1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity|acyldihydroxyacetone phosphate reductase activity|1-acyldihydroxyacetone-phosphate reductase activity											MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN|RHEA:17341|Reactome:R-HSA-75883|EC:1.1.1.101		molecular_function											owl:Class	
GO:0046500	biolink:NamedThing	S-adenosylmethionine metabolic process	The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.	got7fsn_ti	S-adenosyl methionine metabolism|SAM metabolic process|S-adenosyl methionine metabolic process|S-adenosylmethionine metabolism													biological_process											owl:Class	
GO:0047366	biolink:NamedThing	quercetin-3-sulfate 4'-sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,4'-disulfate.	got7fsn_ti	quercetin-3-sulphate 4'-sulphotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 4'-sulfotransferase activity|PAPS:flavonol 3-sulfate 4'-sulfotransferase activity|flavonol 4'-sulfotransferase activity											EC:2.8.2.27|KEGG_REACTION:R02633|MetaCyc:2.8.2.27-RXN|RHEA:17205		molecular_function											owl:Class	
GO:0099549	biolink:NamedThing	trans-synaptic signaling by carbon monoxide	Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.	got7fsn_ti														biological_process											owl:Class	
GO:0032531	biolink:NamedThing	regulation of follicle cell microvillus organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.	got7fsn_ti	regulation of follicle cell microvillus organization and biogenesis|regulation of follicle cell microvillus organisation													biological_process											owl:Class	
GO:0010188	biolink:NamedThing	response to microbial phytotoxin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants.	got7fsn_ti														biological_process											owl:Class	
GO:0018811	biolink:NamedThing	cyclohex-1-ene-1-carboxyl-CoA hydratase activity	Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA.	got7fsn_ti												MetaCyc:R266-RXN|UM-BBD_reactionID:r0191		molecular_function											owl:Class	
GO:0008611	biolink:NamedThing	ether lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.	got7fsn_ti	ether lipid anabolism|ether lipid biosynthesis|plasmalogen biosynthetic process|ether lipid synthesis|ether lipid formation													biological_process											owl:Class	
GO:0018676	biolink:NamedThing	(S)-limonene 7-monooxygenase activity	Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+).	got7fsn_ti	(-)-limonene 7-monooxygenase activity											UM-BBD_reactionID:r0728|RHEA:23432|MetaCyc:--LIMONENE-7-MONOOXYGENASE-RXN|KEGG_REACTION:R02470|EC:1.14.14.52		molecular_function											owl:Class	
GO:0062021	biolink:NamedThing	mitotic cohesin dsDNA (leading strand) loading	The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle.	got7fsn_ti							dph	2018-04-06T13:04:41Z						biological_process											owl:Class	
GO:0046959	biolink:NamedThing	habituation	A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.	got7fsn_ti												Wikipedia:Habituation		biological_process											owl:Class	
GO:0010084	biolink:NamedThing	specification of animal organ axis polarity	The process in which the polarity of an animal organ axis is specified.	got7fsn_ti														biological_process											owl:Class	
GO:0097261	biolink:NamedThing	eoxin C4 synthase activity	Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4.	got7fsn_ti							pr	2012-03-08T02:59:00Z				Reactome:R-HSA-2161768		molecular_function											owl:Class	
GO:0034577	biolink:NamedThing	N-isopropylacetaniline monooxygenase activity	Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone.	got7fsn_ti												UM-BBD_reactionID:r0914|EC:1.14.15.-		molecular_function											owl:Class	
GO:0071797	biolink:NamedThing	LUBAC complex	A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex.	got7fsn_ti							mah	2010-09-02T04:09:55Z						cellular_component											owl:Class	
GO:1990140	biolink:NamedThing	MPT synthase complex	A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.	got7fsn_ti	molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex						pr	2013-07-11T08:32:29Z						cellular_component											owl:Class	
GO:0097671	biolink:NamedThing	SCF-YDR131C ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae.	got7fsn_ti							pr	2014-10-06T10:29:35Z						cellular_component											owl:Class	
GO:0050274	biolink:NamedThing	salicyl-alcohol beta-D-glucosyltransferase activity	Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H(+) + salicin + UDP.	got7fsn_ti	salicyl-alcohol b-D-glucosyltransferase activity|UDP-glucose:salicyl-alcohol beta-D-glucosyltransferase activity|salicyl-alcohol glucosyltransferase activity|UDPglucose:salicyl alcohol phenyl-glucosyltransferase activity|UDPglucose:salicyl-alcohol beta-D-glucosyltransferase activity|uridine diphosphoglucose-salicyl alcohol 2-glucosyltransferase activity											EC:2.4.1.172|RHEA:11512|MetaCyc:SALICYL-ALCOHOL-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R03558		molecular_function											owl:Class	
GO:0046966	biolink:NamedThing	thyroid hormone receptor binding	Binding to a thyroid hormone receptor.	got7fsn_ti	ligand-dependent thyroid hormone receptor interactor activity													molecular_function											owl:Class	
GO:0070703	biolink:NamedThing	outer mucus layer	The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria.	got7fsn_ti							mah	2009-06-08T02:44:51Z						cellular_component											owl:Class	
GO:0004475	biolink:NamedThing	mannose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose.	got7fsn_ti	GDP-mannose pyrophosphorylase activity|GTP-mannose-1-phosphate guanylyltransferase activity|GTP:alpha-D-mannose-1-phosphate guanylyltransferase activity|GTP:mannose-1-phosphate guanylyltransferase activity|guanosine 5'-diphospho-D-mannose pyrophosphorylase activity|guanosine diphosphomannose pyrophosphorylase activity|PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase)|guanosine triphosphate-mannose 1-phosphate guanylyltransferase activity|mannose 1-phosphate guanylyltransferase (guanosine triphosphate)											Reactome:R-HSA-446221|EC:2.7.7.13|RHEA:15229|MetaCyc:2.7.7.13-RXN|KEGG_REACTION:R00885		molecular_function											owl:Class	
GO:0090595	biolink:NamedThing	acetyl-CoA:L-lysine N6-acetyltransferase	Catalysis of the reaction: L-lysine + acetyl-CoA = N6-acetyl-L-lysine + CoA + H(+).	got7fsn_ti							tb	2014-08-21T17:19:06Z						molecular_function											owl:Class	
GO:0098795	biolink:NamedThing	mRNA cleavage involved in gene silencing	Cleavage of an mRNA occurring as part of the mechanism of gene silencing.	got7fsn_ti														biological_process											owl:Class	
GO:0043907	biolink:NamedThing	Cys-tRNA(Pro) hydrolase activity	Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro).	got7fsn_ti	Cys-tRNAPro hydrolase activity|Cys-tRNA(Pro) deacetylase activity											EC:3.1.1.-		molecular_function											owl:Class	
GO:1990609	biolink:NamedThing	glutamate-cysteine ligase regulator activity	Binds to and modulates the activity of glutamate-cysteine ligase.	got7fsn_ti							vw	2015-01-20T12:51:13Z						molecular_function											owl:Class	
GO:0061721	biolink:NamedThing	6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-).	got7fsn_ti							dph	2015-07-01T09:20:08Z				MetaCyc:PWY-7446		biological_process											owl:Class	
GO:0004037	biolink:NamedThing	allantoicase activity	Catalysis of the reaction: allantoate + H(2)O = (S)-ureidoglycolate + urea.	got7fsn_ti	allantoine amidinohydrolase activity|allantoate amidinohydrolase activity											RHEA:11016|EC:3.5.3.4|MetaCyc:ALLANTOICASE-RXN|KEGG_REACTION:R02422		molecular_function											owl:Class	
GO:0003400	biolink:NamedThing	regulation of COPII vesicle coating	Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.	got7fsn_ti							dph	2009-12-17T08:38:14Z						biological_process											owl:Class	
GO:0060013	biolink:NamedThing	righting reflex	A reflex process in which an animal immediately tries to turn over after being placed in a supine position.	got7fsn_ti	righting response													biological_process											owl:Class	
GO:0102927	biolink:NamedThing	beta-chaconine rhamnosyltransferase activity	Catalysis of the reaction: beta-chaconine + UDP-L-rhamnose = H+ + alpha-chaconine + UDP.	got7fsn_ti												MetaCyc:RXN-8883		molecular_function											owl:Class	
GO:0008218	biolink:NamedThing	bioluminescence	The production of light by certain enzyme-catalyzed reactions in cells.	got7fsn_ti												Wikipedia:Bioluminescence		biological_process											owl:Class	
GO:0061625	biolink:NamedThing	glycolytic process through fructose-1-phosphate	The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.	got7fsn_ti							dph	2014-04-29T13:04:10Z						biological_process											owl:Class	
GO:0140238	biolink:NamedThing	presynaptic endocytosis	A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.	got7fsn_ti		https://github.com/geneontology/synapse/issues/230			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T07:33:55Z						biological_process											owl:Class	
GO:0033464	biolink:NamedThing	GGG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GGG codon.	got7fsn_ti	glycine tRNA				Note that in the standard genetic code, GGG codes for glycine.									molecular_function											owl:Class	
GO:0021926	biolink:NamedThing	Golgi cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	got7fsn_ti														biological_process											owl:Class	
GO:0052915	biolink:NamedThing	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.	got7fsn_ti												KEGG_REACTION:R07234|RHEA:42740|MetaCyc:RXN-11574|EC:2.1.1.173		molecular_function											owl:Class	
GO:0035753	biolink:NamedThing	maintenance of DNA trinucleotide repeats	Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.	got7fsn_ti							bf	2011-03-23T10:29:02Z						biological_process											owl:Class	
GO:0050537	biolink:NamedThing	mandelamide amidase activity	Catalysis of the reaction: (R)-mandelamide + H(2)O = (R)-mandelate + NH(4)(+).	got7fsn_ti	mandelamide hydrolase activity|Pseudomonas mandelamide hydrolase activity											KEGG_REACTION:R05783|RHEA:22876|EC:3.5.1.86|MetaCyc:3.5.1.86-RXN		molecular_function											owl:Class	
GO:0019161	biolink:NamedThing	diamine transaminase activity	Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate.	got7fsn_ti	diamine-ketoglutaric transaminase activity|amine-ketoacid transaminase activity|diamine:2-oxoglutarate aminotransferase activity|amine transaminase activity|diamine aminotransferase activity											EC:2.6.1.29|RHEA:18217|MetaCyc:DIAMTRANSAM-RXN		molecular_function											owl:Class	
GO:0036000	biolink:NamedThing	mucocyst	A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion.	got7fsn_ti							bf	2011-09-06T01:32:17Z						cellular_component											owl:Class	
GO:0034532	biolink:NamedThing	2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity	Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.	got7fsn_ti												UM-BBD_reactionID:r0765|EC:5.3.99.-		molecular_function											owl:Class	
GO:0047480	biolink:NamedThing	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.	got7fsn_ti	UDPacetylmuramoylpentapeptide synthetase activity|MurF synthetase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity|UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity|UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity|uridine diphosphoacetylmuramoylpentapeptide synthetase activity|UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)|UDP-MurNAc-pentapeptide synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity				Note that the enzyme UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase also has UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (GO:0008766).							MetaCyc:6.3.2.10-RXN|RHEA:16085|EC:6.3.2.10		molecular_function											owl:Class	
GO:0009026	biolink:NamedThing	tagaturonate reductase activity	Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH.	got7fsn_ti	TagUAR|D-altronate:NAD+ 3-oxidoreductase activity|altronic oxidoreductase activity|altronate oxidoreductase activity|tagaturonate dehydrogenase activity|D-tagaturonate reductase activity|altronate dehydrogenase activity											MetaCyc:ALTRO-OXIDOREDUCT-RXN|KEGG_REACTION:R02555|RHEA:17813|EC:1.1.1.58		molecular_function											owl:Class	
GO:0097185	biolink:NamedThing	cellular response to azide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.	got7fsn_ti							pr	2011-11-16T10:04:41Z						biological_process											owl:Class	
GO:0008480	biolink:NamedThing	sarcosine dehydrogenase activity	Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein.	got7fsn_ti	sarcosine:(acceptor) oxidoreductase (demethylating)|sarcosine:acceptor oxidoreductase (demethylating)|sarcosine N-demethylase activity|monomethylglycine dehydrogenase activity				Note that this was EC:1.5.99.1.							MetaCyc:SARCOSINE-DEHYDROGENASE-RXN|KEGG_REACTION:R00611|Reactome:R-HSA-6797913|EC:1.5.8.3|RHEA:19793		molecular_function											owl:Class	
GO:0047411	biolink:NamedThing	2-(acetamidomethylene)succinate hydrolase activity	Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate.	got7fsn_ti	2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)|alpha-(N-acetylaminomethylene)succinic acid hydrolase activity											EC:3.5.1.29|RHEA:10432|MetaCyc:3.5.1.29-RXN		molecular_function											owl:Class	
GO:0102823	biolink:NamedThing	kaempferol-3-rhamnoside-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol-3-rhamnoside <=> kaempferol 3-O-rhamnoside-7-O-glucoside + UDP.	got7fsn_ti												MetaCyc:RXN-8266		molecular_function											owl:Class	
GO:0047744	biolink:NamedThing	chloridazon-catechol dioxygenase activity	Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O(2) = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+).	got7fsn_ti	5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing)											RHEA:20449|KEGG_REACTION:R04602|EC:1.13.11.36|MetaCyc:CHLORIDAZON-CATECHOL-DIOXYGENASE-RXN		molecular_function											owl:Class	
GO:0102975	biolink:NamedThing	versiconal hemiacetal acetate reductase activity	Catalysis of the reaction: versiconol acetate + NADP <=> versiconal hemiacetal acetate + NADPH.	got7fsn_ti												EC:1.1.1.353|MetaCyc:RXN-9490|RHEA:35695		molecular_function											owl:Class	
GO:0102863	biolink:NamedThing	1-18:3-2-18:1-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:3-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	got7fsn_ti												MetaCyc:RXN-8330		molecular_function											owl:Class	
GO:0047369	biolink:NamedThing	succinate-hydroxymethylglutarate CoA-transferase activity	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate.	got7fsn_ti	succinate:(S)-3-hydroxy-3-methylglutarate CoA-transferase activity|dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase activity|hydroxymethylglutarate coenzyme A-transferase activity											MetaCyc:2.8.3.13-RXN|EC:2.8.3.13|RHEA:12284		molecular_function											owl:Class	
GO:0036381	biolink:NamedThing	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity	Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.	got7fsn_ti	pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) activity|PdxST activity						bf	2013-05-23T11:15:37Z				KEGG_REACTION:R10089|RHEA:31507|EC:4.3.3.6|MetaCyc:RXN-11322		molecular_function											owl:Class	
GO:0047245	biolink:NamedThing	N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity	Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.	got7fsn_ti	UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity|UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase activity|uridine diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol glucosyltransferase activity|UDPglucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity											RHEA:20952|MetaCyc:2.4.1.188-RXN|EC:2.4.1.188		molecular_function											owl:Class	
GO:0000807	biolink:NamedThing	Z chromosome	The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females.	got7fsn_ti												Wikipedia:ZW_sex-determination_system		cellular_component											owl:Class	
GO:0031487	biolink:NamedThing	myosin XVII complex	A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.	got7fsn_ti														cellular_component											owl:Class	
GO:0050966	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of pain	The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.	got7fsn_ti	perception of pain, detection of mechanical stimulus|perception of pain, sensory detection of mechanical stimulus|mechanical nociception|sensory detection of mechanical stimulus during perception of pain|perception of pain, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during perception of pain													biological_process											owl:Class	
GO:0043306	biolink:NamedThing	positive regulation of mast cell degranulation	Any process that activates or increases the frequency, rate or extent of mast cell degranulation.	got7fsn_ti	up-regulation of mast cell degranulation|up regulation of mast cell degranulation|stimulation of mast cell degranulation|upregulation of mast cell degranulation|positive regulation of mast cell granule exocytosis|activation of mast cell degranulation													biological_process											owl:Class	
GO:0102142	biolink:NamedThing	[dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [dermatan]-alpha-L-iduronate <=> adenosine 3',5'-bismonophosphate + [dermatan-sulfate]-2-O-sulfo-alpha-L-iduronate.	got7fsn_ti												MetaCyc:RXN-11561		molecular_function											owl:Class	
GO:0036413	biolink:NamedThing	histone H3-R26 citrullination	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3.	got7fsn_ti	histone H3 arginine 26 citrullination						bf	2013-08-22T13:59:15Z						biological_process											owl:Class	
GO:1990974	biolink:NamedThing	actin-dependent nuclear migration	The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell.	got7fsn_ti	actin-dependent nuclear movement						hjd	2016-06-22T19:17:02Z						biological_process											owl:Class	
GO:0003853	biolink:NamedThing	2-methylacyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor.	got7fsn_ti	branched-chain acyl-CoA dehydrogenase activity|2-methylbutanoyl-CoA:acceptor oxidoreductase activity|2-methylbutanoyl-CoA:(acceptor) oxidoreductase activity|2-methyl branched chain acyl-CoA dehydrogenase activity											MetaCyc:2-METHYLACYL-COA-DEHYDROGENASE-RXN|EC:1.3.99.12|RHEA:13261		molecular_function											owl:Class	
GO:0042785	biolink:NamedThing	evasion of host immune response via regulation of host cytokine network	Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	active immune evasion via regulation of host cytokine network|active evasion of host immune response via regulation of host cytokine network|active evasion of immune response of other organism via regulation of cytokine network of other organism involved in symbiotic interaction|active immune evasion via modulation of host cytokine network										GO:0051812			biological_process											owl:Class	
GO:0102440	biolink:NamedThing	3',4',5'-trimethylmyricetin 3-O-methyltransferase activity	Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine  <=> 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine  + H+.	got7fsn_ti												MetaCyc:RXN-13918		molecular_function											owl:Class	
GO:0008011	biolink:NamedThing	structural constituent of pupal chitin-based cuticle	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster.	got7fsn_ti	structural constituent of pupal cuticle													molecular_function											owl:Class	
GO:1904125	biolink:NamedThing	convergent extension involved in rhombomere morphogenesis	Any convergent extension that is involved in rhombomere morphogenesis.	got7fsn_ti							dph	2015-04-10T21:12:50Z						biological_process											owl:Class	
GO:1990943	biolink:NamedThing	mating type region replication fork barrier binding	Binding to the replication fork barrier found in the mating type region of fission yeast.	got7fsn_ti	RTS1 element binding|RTS1 barrier binding						mah	2016-04-06T16:08:43Z						molecular_function											owl:Class	
GO:0102399	biolink:NamedThing	dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine  + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+.	got7fsn_ti												MetaCyc:RXN-13658		molecular_function											owl:Class	
GO:0031432	biolink:NamedThing	titin binding	Binding to titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.	got7fsn_ti														molecular_function											owl:Class	
GO:0002769	biolink:NamedThing	natural killer cell inhibitory signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.	got7fsn_ti	natural killer cell inhibitory signalling pathway|killer cell inhibitory receptor signaling pathway|NK cell inhibitory signaling pathway|Ly49 inhibitory receptor signaling pathway|inhibitory KIR signaling pathway													biological_process											owl:Class	
GO:0043398	biolink:NamedThing	HLH domain binding	Binding to a Helix Loop Helix domain, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization.	got7fsn_ti														molecular_function											owl:Class	
GO:0071858	biolink:NamedThing	corazonin receptor binding	Binding to a corazonin receptor.	got7fsn_ti							mah	2010-09-10T03:23:40Z						molecular_function											owl:Class	
GO:0071798	biolink:NamedThing	response to prostaglandin D	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.	got7fsn_ti	response to prostaglandin D stimulus						mah	2010-09-03T10:48:03Z						biological_process											owl:Class	
GO:0030782	biolink:NamedThing	(S)-tetrahydroprotoberberine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine.	got7fsn_ti	S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase activity|tetrahydroprotoberberine cis-N-methyltransferase activity											MetaCyc:2.1.1.122-RXN|RHEA:12805|EC:2.1.1.122		molecular_function											owl:Class	
GO:0043274	biolink:NamedThing	phospholipase binding	Binding to a phospholipase.	got7fsn_ti														molecular_function											owl:Class	
GO:0102283	biolink:NamedThing	3-ketodihydrosphinganine (C20) reductase activity	Catalysis of the reaction: C20 sphinganine(1+) + NADP <=> C20 3-dehydrosphinganine(1+) + NADPH + H+.	got7fsn_ti												MetaCyc:RXN-12642		molecular_function											owl:Class	
GO:0043212	biolink:NamedThing	carbohydrate-exporting ABC transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out).	got7fsn_ti	carbohydrate-exporting ATPase activity	https://github.com/geneontology/go-ontology/issues/17289												molecular_function											owl:Class	
GO:0003874	biolink:NamedThing	6-pyruvoyltetrahydropterin synthase activity	Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate.	got7fsn_ti	2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)|PTPS activity|2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity|6-pyruvoyl tetrahydrobiopterin synthase activity											RHEA:22048|KEGG_REACTION:R04286|MetaCyc:4.2.3.12-RXN|Reactome:R-HSA-1474184|EC:4.2.3.12		molecular_function											owl:Class	
GO:0010067	biolink:NamedThing	procambium histogenesis	The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0034296	biolink:NamedThing	zygospore formation	The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.	got7fsn_ti														biological_process											owl:Class	
GO:0042639	biolink:NamedThing	telogen	The resting phase of hair cycle.	got7fsn_ti	hair resting phase				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).									biological_process											owl:Class	
GO:0034806	biolink:NamedThing	benzo(a)pyrene 11,12-dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol.	got7fsn_ti												UM-BBD_reactionID:r1124|EC:1.13.11.-		molecular_function											owl:Class	
GO:0033423	biolink:NamedThing	CCA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CCA codon.	got7fsn_ti	proline tRNA				Note that in the standard genetic code, CCA codes for proline.									molecular_function											owl:Class	
GO:0052604	biolink:NamedThing	delta-tocopherol cyclase activity	Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol.	got7fsn_ti												KEGG_REACTION:R07503|RHEA:37987|MetaCyc:RXN-2561		molecular_function											owl:Class	
GO:0047280	biolink:NamedThing	nicotinamide phosphoribosyltransferase activity	Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide.	got7fsn_ti	NMN synthetase activity|NMN pyrophosphorylase activity|nicotinamide mononucleotide pyrophosphorylase activity|nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|nicotinamide mononucleotide synthetase activity|NMN diphosphorylase activity											KEGG_REACTION:R01271|Reactome:R-HSA-197250|MetaCyc:2.4.2.12-RXN|EC:2.4.2.12|RHEA:16149		molecular_function											owl:Class	
GO:0106387	biolink:NamedThing	'de novo' GMP biosynthetic process	The chemical reactions and pathways resulting in the formation of guanosine 5'-monophosphate (GMP) through an inosine 5'-monophosphate (IMP) intermediate.	got7fsn_ti	'de novo' guanosine 5'-monophosphate biosynthetic process						hjd	2021-07-07T17:27:01Z						biological_process											owl:Class	
GO:0008864	biolink:NamedThing	formyltetrahydrofolate deformylase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+).	got7fsn_ti	10-formyltetrahydrofolate amidohydrolase activity|formyltetrahydrofolate hydrolase activity|formyl-FH(4) hydrolase activity											KEGG_REACTION:R00944|EC:3.5.1.10|MetaCyc:FORMYLTHFDEFORMYL-RXN|RHEA:19833		molecular_function											owl:Class	
GO:1990388	biolink:NamedThing	xylem-to-phloem iron transport	The directed movement of iron ions into the phloem from the xylem.	got7fsn_ti							tb	2014-05-30T21:06:50Z						biological_process											owl:Class	
GO:0034231	biolink:NamedThing	islet amyloid polypeptide processing	The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).	got7fsn_ti	IAPP processing|islet amyloid peptide formation|IAPP formation|islet amyloid polypeptide formation|islet amyloid peptide processing													biological_process											owl:Class	
GO:0098803	biolink:NamedThing	respiratory chain complex	Any protein complex that is part of a respiratory chain.	got7fsn_ti														cellular_component											owl:Class	
GO:0097075	biolink:NamedThing	interferon regulatory factor 3-interferon regulatory factor 7 complex	An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7.	got7fsn_ti	IRF3:IRF7 complex						pr	2011-06-15T04:33:36Z						cellular_component											owl:Class	
GO:0140623	biolink:NamedThing	type I pilus assembly	The assembly from its constituent parts of a type I pilus.	got7fsn_ti	type I fimbrial assembly|type I fimbriae biogenesis|type I fimbria biogenesis|T1P assembly|type I fimbrium assembly|type 1 pilus biogenesis|type I fimbriae assembly|type I fimbria assembly|type I fimbrial biogenesis|type I fimbrium biogenesis	https://github.com/geneontology/go-ontology/issues/14469					pg	2021-03-10T12:23:20Z						biological_process											owl:Class	
GO:0051617	biolink:NamedThing	negative regulation of histamine uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.	got7fsn_ti	down regulation of histamine uptake|negative regulation of histamine import|downregulation of histamine uptake|down-regulation of histamine uptake													biological_process											owl:Class	
GO:0032021	biolink:NamedThing	NELF complex	A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.	got7fsn_ti	negative elongation factor complex													cellular_component											owl:Class	
GO:0060584	biolink:NamedThing	regulation of prostaglandin-endoperoxide synthase activity	Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.	got7fsn_ti	regulation of (PG)H synthase activity|regulation of PG synthetase activity|regulation of fatty acid cyclooxygenase activity|regulation of prostaglandin synthetase activity						dph	2009-05-08T02:08:37Z						biological_process											owl:Class	
GO:0051697	biolink:NamedThing	protein delipidation	The breakage of covalent bonds to detach lipid groups from a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0019810	biolink:NamedThing	putrescine binding	Binding to putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.	got7fsn_ti														molecular_function											owl:Class	
GO:0140366	biolink:NamedThing	galectin lattice	A non-stoichiometric protein complex formed by several galectins crosslinking glycosylated ligands to form a dynamic lattice. The galectin lattice modulates receptor kinase signaling and the functionality of membrane receptors, by regulating the diffusion, compartmentalization and endocytosis of plasma membrane glycoproteins and glycolipids.	got7fsn_ti							pg	2019-07-25T19:35:05Z						cellular_component											owl:Class	
GO:0098635	biolink:NamedThing	protein complex involved in cell-cell adhesion	Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.	got7fsn_ti														cellular_component											owl:Class	
GO:0034970	biolink:NamedThing	histone H3-R2 methylation	The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone.	got7fsn_ti	histone lysine H3 R2 methylation|histone H3 R2 methylation|histone H3R2me													biological_process											owl:Class	
GO:0019509	biolink:NamedThing	L-methionine salvage from methylthioadenosine	The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.	got7fsn_ti	methionine salvage from methylthioadenosine|methionine recycling|methionine salvage pathway|methionine regeneration											MetaCyc:PWY-4361		biological_process											owl:Class	
GO:0042913	biolink:NamedThing	group A colicin transmembrane transporter activity	Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0010494	biolink:NamedThing	cytoplasmic stress granule	A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.	got7fsn_ti	cytoplasmic mRNP granule|stress granule											Wikipedia:Stress_granule		cellular_component											owl:Class	
GO:0102708	biolink:NamedThing	S-adenosyl-L-methionine:N-methyl-beta-alanine N-methyltransferase activity	Catalysis of the reaction: N-methyl-beta-alanine + S-adenosyl-L-methionine  = H+ + N,N-dimethyl-beta-alanine + S-adenosyl-L-homocysteine.	got7fsn_ti												MetaCyc:RXN-6462		molecular_function											owl:Class	
GO:0008893	biolink:NamedThing	guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate.	got7fsn_ti	penta-phosphate guanosine-3'-diphosphohydrolase activity|penta-phosphate guanosine-3'-pyrophosphohydrolase activity|guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase activity|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase activity|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase activity|PpGpp phosphohydrolase activity|PpGpp-3'-pyrophosphohydrolase activity|(ppGpp)ase activity											RHEA:14253|MetaCyc:PPGPPSYN-RXN|EC:3.1.7.2		molecular_function											owl:Class	
GO:0047509	biolink:NamedThing	(R)-dehydropantoate dehydrogenase activity	Catalysis of the reaction: (R)-4-dehydropantoate + H(2)O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH.	got7fsn_ti	(R)-4-dehydropantoate:NAD+ 4-oxidoreductase activity|D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase activity|D-aldopantoate dehydrogenase activity											MetaCyc:R-DEHYDROPANTOATE-DEHYDROGENASE-RXN|RHEA:19349|EC:1.2.1.33|KEGG_REACTION:R03198		molecular_function											owl:Class	
GO:0075507	biolink:NamedThing	entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome	Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm.	got7fsn_ti					This mechanism is used by viruses such as Herpesvirales whose capsid is too large to enter the nuclear pore complex (NPC) pore.		jl	2011-07-26T04:52:51Z						biological_process											owl:Class	
GO:0071521	biolink:NamedThing	Cdc42 GTPase complex	A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway.	got7fsn_ti	Ras1-Scd1-Scd2-Cdc42-Shk1 complex						mah	2010-01-07T01:29:12Z						cellular_component											owl:Class	
GO:0080048	biolink:NamedThing	GDP-D-glucose phosphorylase activity	Catalysis of the reaction: GDP-D-glucose + phosphate = D-glucose-1-P + GDP.	got7fsn_ti												RHEA:30387|EC:2.7.7.78|MetaCyc:RXN-12486		molecular_function											owl:Class	
GO:0047169	biolink:NamedThing	galactarate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA.	got7fsn_ti	galacturate hydroxycinnamoyltransferase activity|feruloyl-CoA:galactarate O-(hydroxycinnamoyl)transferase activity											EC:2.3.1.130|MetaCyc:2.3.1.130-RXN|RHEA:12997|KEGG_REACTION:R03727		molecular_function											owl:Class	
GO:0102462	biolink:NamedThing	quercetin 3-sophoroside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> quercetin 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP + H+.	got7fsn_ti												MetaCyc:RXN-14011		molecular_function											owl:Class	
GO:0102907	biolink:NamedThing	sesquisabinene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + sesquisabinene.	got7fsn_ti												MetaCyc:RXN-8622		molecular_function											owl:Class	
GO:1990656	biolink:NamedThing	t-SNARE clustering	The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies.	got7fsn_ti							sl	2015-02-25T00:18:33Z						biological_process											owl:Class	
GO:0016058	biolink:NamedThing	maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling	Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon.	got7fsn_ti	maintenance of rhodopsin mediated signaling|maintenance of rhodopsin mediated signalling													biological_process											owl:Class	
GO:0033534	biolink:NamedThing	verbascose biosynthetic process	The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	verbascose synthesis|verbascose anabolism|verbascose biosynthesis|verbascose formation													biological_process											owl:Class	
GO:0031697	biolink:NamedThing	beta-1 adrenergic receptor binding	Binding to a beta-1 adrenergic receptor.	got7fsn_ti	beta-1 adrenergic receptor ligand													molecular_function											owl:Class	
GO:0090474	biolink:NamedThing	arg-arg specific dibasic protein processing	Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein.	got7fsn_ti							tb	2012-10-01T10:42:30Z						biological_process											owl:Class	
GO:0097686	biolink:NamedThing	dinoflagellate apical horn	A horn-shaped dinoflagellate apex found in thecate species.	got7fsn_ti							pr	2014-12-18T09:38:15Z						cellular_component											owl:Class	
GO:0060367	biolink:NamedThing	sagittal suture morphogenesis	The process in which the sagittal suture is generated and organized.	got7fsn_ti														biological_process											owl:Class	
GO:0140446	biolink:NamedThing	fumigermin biosynthetic process	The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus.	got7fsn_ti	fumigermin synthesis|fumigermin biosynthesis|fumigermin anabolism|fumigermin formation						pg	2020-03-31T12:02:29Z						biological_process											owl:Class	
GO:0034303	biolink:NamedThing	myxospore formation	The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria.	got7fsn_ti														biological_process											owl:Class	
GO:0001641	biolink:NamedThing	group II metabotropic glutamate receptor activity	A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.	got7fsn_ti														molecular_function											owl:Class	
GO:0019656	biolink:NamedThing	glucose catabolic process to D-lactate and ethanol	The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule.	got7fsn_ti	heterolactate fermentation|heterofermentative lactate fermentation|heterolactic fermentation|heterofermentative pathway|glucose fermentation to D-lactate and ethanol|heterofermentation											MetaCyc:P122-PWY		biological_process											owl:Class	
GO:0014868	biolink:NamedThing	cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction	A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0070068	biolink:NamedThing	VAMP4-syntaxin-6-syntaxin-16-Vti1a complex	A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).	got7fsn_ti	SNARE complex (Vamp4, Stx6, Stx16, Vti1a)|Vamp4-Stx6-Stx16-Vti1a complex													cellular_component											owl:Class	
GO:0140680	biolink:NamedThing	histone H3-di/monomethyl-lysine-36 demethylase activity	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	got7fsn_ti	histone H3K36me2 demethylase activity|histone H3K36me demethylase activity	https://github.com/geneontology/go-ontology/issues/21089					pg	2021-07-08T14:12:22Z				MetaCyc: RXN-8661|RHEA:42032|EC:1.14.11.27		molecular_function											owl:Class	
GO:0061842	biolink:NamedThing	microtubule organizing center localization	Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	MTOC localization|MTOC polarity|microtubule organizing center polarity													biological_process											owl:Class	
GO:0102731	biolink:NamedThing	D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity	Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP.	got7fsn_ti												MetaCyc:RXN-7185		molecular_function											owl:Class	
GO:0014731	biolink:NamedThing	spectrin-associated cytoskeleton	The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0061978	biolink:NamedThing	mandibular condyle articular cartilage development	The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure.	got7fsn_ti							dph	2018-02-12T20:04:49Z						biological_process											owl:Class	
GO:0050412	biolink:NamedThing	cinnamate beta-D-glucosyltransferase activity	Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP.	got7fsn_ti	uridine diphosphoglucose-cinnamate glucosyltransferase activity|UDP-glucose:trans-cinnamate beta-D-glucosyltransferase activity|cinnamate b-D-glucosyltransferase activity|cinnamate glucosyltransferase activity|UDPglucose:trans-cinnamate beta-D-glucosyltransferase activity|UDPG:t-cinnamate glucosyltransferase activity											RHEA:13437|EC:2.4.1.177|MetaCyc:CINNAMATE-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R02256		molecular_function											owl:Class	
GO:0033751	biolink:NamedThing	linoleate 8R-lipoxygenase	Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate.	got7fsn_ti	7,8-linoleate diol synthase (bifunctional enzyme)|5,8-linoleate diol synthase (bifunctional enzyme)|linoleate diol synthase activity											RHEA:22392		molecular_function											owl:Class	
GO:1990137	biolink:NamedThing	plant seed peroxidase activity	Catalysis of the reaction: R1H + R2OOH = R1OH + R2OH.	got7fsn_ti	peroxygenase activity						tb	2013-07-03T12:49:20Z				MetaCyc:RXN-11819|EC:1.11.2.3		molecular_function											owl:Class	
GO:0050332	biolink:NamedThing	thiamine pyridinylase activity	Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine.	got7fsn_ti	pyrimidine transferase activity|thiamin hydrolase activity|thiamin pyridinylase activity|thiamine pyridinolase activity|thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity|thiamin pyridinolase activity|thiamine hydrolase activity|thiaminase I activity|thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity											RHEA:17697|MetaCyc:THIAMIN-PYRIDINYLASE-RXN|EC:2.5.1.2|KEGG_REACTION:R02863		molecular_function											owl:Class	
GO:0052640	biolink:NamedThing	salicylic acid glucosyltransferase (glucoside-forming) activity	Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP.	got7fsn_ti	UDP:glucose:SA glucosyltransferase (glucoside-forming) activity|UDP:glucose:salicylic acid glucosyltransferase (glucoside-forming) activity|salicylic acid glucosyltransferase activity|UDP:glucose:salicylate glucosyltransferase (glucoside-forming) activity|UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (glucoside-forming) activity											MetaCyc:RXN-11658|RHEA:62312		molecular_function											owl:Class	
GO:0048543	biolink:NamedThing	phytochrome chromophore biosynthetic process	The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.	got7fsn_ti	phytochrome chromophore anabolism|phytochrome chromophore formation|phytochrome chromophore synthesis|phytochrome chromophore biosynthesis													biological_process											owl:Class	
GO:1990597	biolink:NamedThing	AIP1-IRE1 complex	A protein complex consisting of IRE1 (inositol-requiring enzyme-1) bound to AIP1 (ASK1-interacting protein 1/DAB2-interacting protein).	got7fsn_ti	AIP1-ERN1 complex|IRE1alpha-AIP1 complex|IRE1-DAB2IP complex						bf	2015-01-05T15:14:35Z						cellular_component											owl:Class	
GO:0047918	biolink:NamedThing	GDP-mannose 3,5-epimerase activity	Catalysis of the reaction: GDP-mannose = GDP-L-galactose.	got7fsn_ti	GDPmannose 3,5-epimerase activity|guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase activity|GDP-D-mannose:GDP-L-galactose epimerase activity											MetaCyc:RXN-1882|EC:5.1.3.18|RHEA:11144		molecular_function											owl:Class	
GO:0009046	biolink:NamedThing	zinc D-Ala-D-Ala carboxypeptidase activity	Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine.	got7fsn_ti	D-alanyl-D-alanine-cleaving carboxypeptidase activity|DD-carboxypeptidase-transpeptidase activity|G enzyme|Zn(2+) G peptidase activity|D-alanyl-D-alanine hydrolase activity|Zn2+ G peptidase activity|DD-carboxypeptidase											MetaCyc:3.4.17.14-RXN|EC:3.4.17.14		molecular_function											owl:Class	
GO:0047398	biolink:NamedThing	dolichylphosphate-mannose phosphodiesterase activity	Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose.	got7fsn_ti	mannosylphosphodolichol phosphodiesterase activity|dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase activity											EC:3.1.4.49|MetaCyc:3.1.4.49-RXN|RHEA:12989		molecular_function											owl:Class	
GO:0103015	biolink:NamedThing	4-amino-4-deoxy-L-arabinose transferase activity	Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate  = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate.	got7fsn_ti												RHEA:35371|MetaCyc:RXN0-2001|EC:2.4.2.43		molecular_function											owl:Class	
GO:0007633	biolink:NamedThing	pattern orientation	The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes.	got7fsn_ti	behavioural response to pattern orientation|behavioral response to pattern orientation													biological_process											owl:Class	
GO:0048014	biolink:NamedThing	Tie signaling pathway	The series of molecular signals generated as a consequence of a Tie protein (a receptor) binding to one of its physiological ligands (an angiopoietin).	got7fsn_ti	Tie receptor signalling pathway|angiopoietin-Tie signaling pathway|Tek receptor signaling|Tie receptor signaling pathway|angiopoietin/Tie signaling pathway													biological_process											owl:Class	
GO:0018464	biolink:NamedThing	3-hydroxypimeloyl-CoA dehydrogenase activity	Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD(+) = 3-oxopimelyl-CoA + H(+) + NADH.	got7fsn_ti	3-hydroxypimeloyl-CoA:NAD+ oxidoreductase activity											EC:1.1.1.259|KEGG_REACTION:R05305|RHEA:11168|UM-BBD_reactionID:r0196|MetaCyc:1.1.1.259-RXN		molecular_function											owl:Class	
GO:0120275	biolink:NamedThing	cerebral blood circulation	The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products.	got7fsn_ti	telencephelon blood circulation|cerebrum blood circulation	https://github.com/geneontology/go-ontology/issues/20107					krc	2020-10-20T19:13:51Z						biological_process											owl:Class	
GO:0005954	biolink:NamedThing	calcium- and calmodulin-dependent protein kinase complex	An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins.	got7fsn_ti	CAMK2|calcium/calmodulin-dependent protein kinase complex|CaMKII													cellular_component											owl:Class	
GO:0044530	biolink:NamedThing	supraspliceosomal complex	Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing.	got7fsn_ti	supraspliceosome complex						jl	2012-03-15T03:33:08Z						cellular_component											owl:Class	
GO:0042561	biolink:NamedThing	alpha-amyrin synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin.	got7fsn_ti												MetaCyc:RXN-8434		molecular_function											owl:Class	
GO:0018459	biolink:NamedThing	carveol dehydrogenase activity	Catalysis of the reaction: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH.	got7fsn_ti	(-)-trans-carveol dehydrogenase activity|(-)-trans-carveol:NADP+ oxidoreductase activity											EC:1.1.1.243|KEGG_REACTION:R03114|MetaCyc:CARVEOL-DEHYDROGENASE-RXN|UM-BBD_reactionID:r0714|RHEA:13629		molecular_function											owl:Class	
GO:0004047	biolink:NamedThing	aminomethyltransferase activity	Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.	got7fsn_ti	protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|glycine synthase activity|protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|T-protein|glycine-cleavage system T-protein activity|tetrahydrofolate aminomethyltransferase activity|S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity											MetaCyc:GCVT-RXN|RHEA:16945|Reactome:R-HSA-5693977|EC:2.1.2.10		molecular_function											owl:Class	
GO:0035049	biolink:NamedThing	juvenile hormone acid methyltransferase activity	Catalysis of the transfer of a methyl group to juvenile hormone acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0106249	biolink:NamedThing	Nicalin-NOMO complex	A protein complex regulating Nodal signaling. Subunits are highly conserved in vertebrates and include Nicalin, NOMO and TMEM147.	got7fsn_ti	Nicalin-TMEM147-NOMO complex						hjd	2020-02-18T17:51:43Z						cellular_component											owl:Class	
GO:0009837	biolink:NamedThing	fruit ripening, non-climacteric	A fruit ripening process that does not involve a respiratory burst.	got7fsn_ti														biological_process											owl:Class	
GO:0031488	biolink:NamedThing	myosin XVIII complex	A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.	got7fsn_ti														cellular_component											owl:Class	
GO:0102100	biolink:NamedThing	mycothiol-arsenate ligase activity	Catalysis of the reaction: arsenate + mycothiol <=> mycothiol-arsenate conjugate + H2O.	got7fsn_ti												RHEA:27349|EC:2.8.4.2|MetaCyc:RXN-11187		molecular_function											owl:Class	
GO:1990738	biolink:NamedThing	pseudouridine 5'-phosphatase activity	Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate.	got7fsn_ti							vw	2015-05-02T11:05:50Z				EC:3.1.3.96|RHEA:10944		molecular_function											owl:Class	
GO:0035741	biolink:NamedThing	activated CD4-positive, alpha-beta T cell proliferation	The expansion of an activated CD4-positive, alpha-beta T cell population by cell division.	got7fsn_ti							bf	2011-03-17T02:18:39Z						biological_process											owl:Class	
GO:0140414	biolink:NamedThing	phosphopantetheine-dependent carrier activity	Binding a substrate via a thioester at the terminal thiol of a covalentely linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate.	got7fsn_ti	carrier protein activity						pg	2020-01-14T16:15:04Z						molecular_function											owl:Class	
GO:1901770	biolink:NamedThing	daunorubicin catabolic process	The chemical reactions and pathways resulting in the breakdown of daunorubicin.	got7fsn_ti	daunorubicin breakdown|daunorubicin degradation|daunorubicin catabolism						yaf	2013-01-15T10:14:29Z						biological_process											owl:Class	
GO:0035393	biolink:NamedThing	chemokine (C-X-C motif) ligand 9 production	The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	Monokine induced by gamma interferon production|CXCL9 production|MIG production						bf	2010-03-23T10:03:20Z						biological_process											owl:Class	
GO:0004617	biolink:NamedThing	phosphoglycerate dehydrogenase activity	Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+.	got7fsn_ti	D- and L-HGA|3-phosphoglycerate dehydrogenase activity|3-phosphoglyceric acid dehydrogenase activity|phosphoglycerate oxidoreductase activity|alphaKG reductase activity|D-3-phosphoglycerate:NAD+ oxidoreductase activity|glycerate-1,3-phosphate dehydrogenase activity|glycerate 3-phosphate dehydrogenase activity|3PHP reductase activity|3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity|D-3-phosphoglycerate dehydrogenase activity|PGDH activity|3-phosphoglycerate:NAD+ 2-oxidoreductase activity|SerA|alpha-KG reductase activity|alpha-phosphoglycerate dehydrogenase activity|SerA 3PG dehydrogenase activity|phosphoglyceric acid dehydrogenase activity											Reactome:R-HSA-977348|EC:1.1.1.95|MetaCyc:PGLYCDEHYDROG-RXN|RHEA:12641		molecular_function											owl:Class	
GO:0036333	biolink:NamedThing	hepatocyte homeostasis	Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.	got7fsn_ti							bf	2012-09-05T10:17:07Z						biological_process											owl:Class	
GO:0016600	biolink:NamedThing	flotillin complex	A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae.	got7fsn_ti					See also the cellular component term 'caveola ; GO:0005901'.									cellular_component											owl:Class	
GO:0032537	biolink:NamedThing	host-seeking behavior	The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host.	got7fsn_ti	host-seeking behaviour													biological_process											owl:Class	
GO:0043242	biolink:NamedThing	negative regulation of protein-containing complex disassembly	Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.	got7fsn_ti	inhibition of protein complex disassembly|negative regulation of protein complex disassembly|downregulation of protein complex disassembly|down-regulation of protein complex disassembly|down regulation of protein complex disassembly													biological_process											owl:Class	
GO:0030153	biolink:NamedThing	bacteriocin immunity	A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.	got7fsn_ti														biological_process											owl:Class	
GO:0004425	biolink:NamedThing	indole-3-glycerol-phosphate synthase activity	Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O.	got7fsn_ti	indoleglycerol phosphate synthase activity|indole-3-glycerophosphate synthase activity|1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)|1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming]|indoleglycerol phosphate synthetase activity											RHEA:23476|MetaCyc:IGPSYN-RXN|EC:4.1.1.48		molecular_function											owl:Class	
GO:0014841	biolink:NamedThing	skeletal muscle satellite cell proliferation	The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.	got7fsn_ti														biological_process											owl:Class	
GO:1990115	biolink:NamedThing	RNA polymerase III assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex.	got7fsn_ti	DNA-directed RNA polymerase III complex assembly|RNA Polymerase III complex assembly						rb	2013-05-31T21:49:19Z						biological_process											owl:Class	
GO:0036369	biolink:NamedThing	transcription factor catabolic process	The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	got7fsn_ti	transcription factor breakdown|sequence-specific DNA binding transcription factor catabolic process|transcription factor catabolism|proteasome-mediated transcription factor catabolism|transcription factor degradation						bf	2012-10-05T10:53:55Z						biological_process											owl:Class	
GO:0042865	biolink:NamedThing	pyochelin catabolic process	The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).	got7fsn_ti	pyochelin catabolism|pyochelin breakdown|pyochelin degradation													biological_process											owl:Class	
GO:0071102	biolink:NamedThing	alpha4-beta1 integrin-paxillin complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin.	got7fsn_ti	ITGA4-ITGB1-PXN complex						mah	2009-11-06T04:53:22Z						cellular_component											owl:Class	
GO:0102880	biolink:NamedThing	isobazzanene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> isobazzanene + diphosphoric acid.	got7fsn_ti												MetaCyc:RXN-8419		molecular_function											owl:Class	
GO:0061898	biolink:NamedThing	all-trans retinoic acid 3,4-desaturase activity	Catalysis of the reaction: all-trans-retinoic acid + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin].	got7fsn_ti							dph	2017-06-12T15:01:23Z						molecular_function											owl:Class	
GO:0075328	biolink:NamedThing	formation of arbuscule for nutrient acquisition	The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	formation by symbiont of arbuscule for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305			Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0098820	biolink:NamedThing	trans-synaptic protein complex	A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes.	got7fsn_ti														cellular_component											owl:Class	
GO:0102207	biolink:NamedThing	docosanoate omega-hydroxylase activity	Catalysis of the reaction: docosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 22-hydroxydocosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	got7fsn_ti	behenate omega-hydroxylase activity	https://github.com/geneontology/go-ontology/issues/19925										MetaCyc:RXN-12155|RHEA:40079		molecular_function											owl:Class	
GO:0047672	biolink:NamedThing	anthranilate N-benzoyltransferase activity	Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA.	got7fsn_ti	benzoyl-CoA:anthranilate N-benzoyltransferase											MetaCyc:ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN|RHEA:21600|KEGG_REACTION:R02453|EC:2.3.1.144		molecular_function											owl:Class	
GO:0098865	biolink:NamedThing	modification by symbiont of host bicellular tight junctions	The process in which an organism effects a change in the structure or function of its host bicellular tight junctions, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.	got7fsn_ti														biological_process											owl:Class	
GO:0039721	biolink:NamedThing	peristromal region viral factory	A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses.	got7fsn_ti	PR						bf	2013-12-19T15:54:00Z						cellular_component											owl:Class	
GO:0043127	biolink:NamedThing	negative regulation of 1-phosphatidylinositol 4-kinase activity	Any process that stops or reduces the activity of the enzyme 1-phosphatidylinositol 4-kinase.	got7fsn_ti	down-regulation of 1-phosphatidylinositol 4-kinase activity|downregulation of 1-phosphatidylinositol 4-kinase activity|inhibition of 1-phosphatidylinositol 4-kinase activity|down regulation of 1-phosphatidylinositol 4-kinase activity|negative regulation of PI4K activity													biological_process											owl:Class	
GO:0007225	biolink:NamedThing	patched ligand maturation	The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.	got7fsn_ti	hh protein processing|patched ligand processing|Hedgehog protein processing													biological_process											owl:Class	
GO:0043976	biolink:NamedThing	histone H3-K79 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 79 of the histone.	got7fsn_ti	histone H3 acetylation at K79|histone H3K79 acetylation													biological_process											owl:Class	
CHEBI:18111	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000252	biolink:NamedThing			got7fsn_ti																									owl:Class	
BFO:0000023	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50906	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36080	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17843	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000253	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33699	biolink:NamedThing			got7fsn_ti																									owl:Class	
GOREL:0001019	biolink:NamedThing	results_in_division_of		got7fsn_ti					use occurs_in|use occurs_in							GOREL:0001019|GOREL:0001019		external|external									results_in_division_of|results_in_division_of		owl:ObjectProperty	
RO:0000057	biolink:NamedThing	has participant		got7fsn_ti												RO:0000057|RO:0000057		external|external									has_participant|has_participant		owl:ObjectProperty	
RO:0012003	biolink:NamedThing	acts on population of		got7fsn_ti												RO:0012003|RO:0012003		external|external									acts_on_population_of|acts_on_population_of		owl:ObjectProperty	
RO:0002212	biolink:NamedThing	negatively regulates		got7fsn_ti												RO:0002212|RO:0002212		external|external									negatively_regulates|negatively_regulates		owl:ObjectProperty	
RO:0002211	biolink:NamedThing	regulates		got7fsn_ti												RO:0002211|RO:0002211		external|external									regulates|regulates		owl:ObjectProperty	
GOREL:0002004	biolink:NamedThing	results_in_fission_of		got7fsn_ti												GOREL:0002004|GOREL:0002004		external|external									results_in_fission_of|results_in_fission_of		owl:ObjectProperty	
RO:0002092	biolink:NamedThing	happens during		got7fsn_ti												RO:0002092|RO:0002092		external|external									happens_during|happens_during		owl:ObjectProperty	
RO:0002093	biolink:NamedThing	ends_during		got7fsn_ti												RO:0002093|RO:0002093		external|external									ends_during|ends_during		owl:ObjectProperty	
GOREL:0002002	biolink:NamedThing	obsolete results_in_disassembly_of		got7fsn_ti										True|True		GOREL:0002002|GOREL:0002002											results_in_disassembly_of|results_in_disassembly_of		owl:ObjectProperty	
RO:0002590	biolink:NamedThing	results_in_disassembly_of		got7fsn_ti												RO:0002590|RO:0002590		external|external									results_in_disassembly_of|results_in_disassembly_of		owl:ObjectProperty	
GOREL:0002001	biolink:NamedThing	obsolete results_in_assembly_of		got7fsn_ti										True|True		GOREL:0002001|GOREL:0002001											results_in_assembly_of|results_in_assembly_of		owl:ObjectProperty	
RO:0002588	biolink:NamedThing	results_in_assembly_of		got7fsn_ti												RO:0002588|RO:0002588		external|external									results_in_assembly_of|results_in_assembly_of		owl:ObjectProperty	
RO:0002592	biolink:NamedThing	results in organization of		got7fsn_ti												RO:0002592|RO:0002592		external|external									results_in_organization_of|results_in_organization_of		owl:ObjectProperty	
GOREL:0001006	biolink:NamedThing	acts_on_population_of		got7fsn_ti	alters levels of				Note that many annotation extensions use regulates_o_acts_on_population_of - should this be considered regulation of number of cells / cell homeostasis?|Note that many annotation extensions use regulates_o_acts_on_population_of - should this be considered regulation of number of cells / cell homeostasis?							GOREL:0001006|GOREL:0001006											acts_on_population_of|acts_on_population_of		owl:ObjectProperty	
GOREL:0002007	biolink:NamedThing	obsolete results_in_remodeling_of		got7fsn_ti										True|True		GOREL:0002007|GOREL:0002007											results_in_remodeling_of|results_in_remodeling_of		owl:ObjectProperty	
RO:0002591	biolink:NamedThing	results in remodeling of		got7fsn_ti												RO:0002591|RO:0002591		external|external									results_in_remodeling_of|results_in_remodeling_of		owl:ObjectProperty	
RO:0002213	biolink:NamedThing	positively regulates		got7fsn_ti												RO:0002213|RO:0002213		external|external									positively_regulates|positively_regulates		owl:ObjectProperty	
GOREL:0012006	biolink:NamedThing	results_in_maintenance_of		got7fsn_ti												GOREL:0012006|GOREL:0012006		external|external									results_in_maintenance_of|results_in_maintenance_of		owl:ObjectProperty	
GOREL:0002006	biolink:NamedThing	obsolete results_in_organization_of		got7fsn_ti										True|True		GOREL:0002006|GOREL:0002006											results_in_organization_of|results_in_organization_of		owl:ObjectProperty	
OBO:go/extensions/ro_pending#results_in_connection_of	biolink:NamedThing	obsolete results_in_connection_of		got7fsn_ti					will be replaced by has_input|will be replaced by has_input					True|True															owl:ObjectProperty	
RO:0012008	biolink:NamedThing	results in fusion of		got7fsn_ti												RO:0012008|RO:0012008		external|external									results_in_fusion_of|results_in_fusion_of		owl:ObjectProperty	
BFO:0000050	biolink:NamedThing	part of		got7fsn_ti												BFO:0000050|BFO:0000050		external|external									part_of|part_of		owl:ObjectProperty	
BFO:0000051	biolink:NamedThing	has part		got7fsn_ti												BFO:0000051|BFO:0000051		external|external									has_part|has_part		owl:TransitiveProperty	
GO:0036326	biolink:NamedThing			got7fsn_ti										True															owl:Class	
IAO:0000227	biolink:NamedThing			got7fsn_ti																										
GOP:goslim_chembl	biolink:NamedThing			got7fsn_ti					ChEMBL protein targets summary																				owl:AnnotationProperty	
GO:1904804	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:goslim_drosophila	biolink:NamedThing			got7fsn_ti					Drosophila GO slim																				owl:AnnotationProperty	
GOP:goslim_pir	biolink:NamedThing			got7fsn_ti					PIR GO slim																				owl:AnnotationProperty	
GO:0072568	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052250	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072642	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990746	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052303	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010627	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061022	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007511	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902504	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042345	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019949	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902403	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035427	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019088	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051527	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045072	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042378	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901662	biolink:NamedThing	quinone catabolic process	The chemical reactions and pathways resulting in the breakdown of quinone.	got7fsn_ti	quinone cofactor catabolic process|quinone degradation|quinone cofactor catabolism|quinone cofactor breakdown|quinone cofactor degradation|quinone breakdown|quinone catabolism						pr	2012-11-20T14:44:44Z			GO:0042378			biological_process											owl:Class	
GO:0103115	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035634	biolink:NamedThing	response to stilbenoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.	got7fsn_ti							bf	2011-01-12T10:37:33Z						biological_process											owl:Class	
GO:0070870	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070829	biolink:NamedThing	obsolete heterochromatin maintenance	OBSOLETE. The chromatin organization process that preserves heterochromatin in a stable functional or structural state.	got7fsn_ti	maintenance of heterochromatic silencing|maintenance of chromatin silencing|heterochromatin maintenance involved in chromatin silencing	https://github.com/geneontology/go-ontology/issues/22013			This term was obsoleted because it is redundant with heterochromatin organization and assembly terms.		mah	2009-07-23T04:14:49Z		True	GO:0070870|GO:0006344			biological_process											owl:Class	
GOP:goslim_pombe	biolink:NamedThing			got7fsn_ti					Fission yeast GO slim																				owl:AnnotationProperty	
GO:0006861	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901688	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:goslim_agr	biolink:NamedThing			got7fsn_ti					AGR slim																				owl:AnnotationProperty	
GO:0051830	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031793	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061020	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:goslim_yeast	biolink:NamedThing			got7fsn_ti					Yeast GO slim																				owl:AnnotationProperty	
GO:1905964	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097319	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098704	biolink:NamedThing	carbohydrate import across plasma membrane	The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	carbohydrate import into cell						pr	2012-05-31T02:45:02Z			GO:0097319			biological_process											owl:Class	
GO:1902469	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:gocheck_do_not_annotate	biolink:NamedThing			got7fsn_ti					Term not to be used for direct annotation																				owl:AnnotationProperty	
GO:0015162	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015084	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090608	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000130	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099168	biolink:NamedThing	extrinsic component of postsynaptic specialization membrane of symmetric synapse	The component of the postsynaptic specialization membrane of a symmetric synapse consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti							dos	2017-09-10T12:00:26Z						cellular_component											owl:Class	
GOP:goslim_synapse	biolink:NamedThing			got7fsn_ti					synapse GO slim																				owl:AnnotationProperty	
GOP:goslim_generic	biolink:NamedThing			got7fsn_ti					Generic GO slim																				owl:AnnotationProperty	
GO:0012504	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010741	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001034	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:4930	biolink:NamedThing			got7fsn_ti																									owl:Class	
GOP:goslim_flybase_ribbon	biolink:NamedThing			got7fsn_ti					FlyBase Drosophila GO ribbon slim																				owl:AnnotationProperty	
GO:0003764	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:goslim_metagenomics	biolink:NamedThing			got7fsn_ti					Metagenomics GO slim																				owl:AnnotationProperty	
GO:0016786	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099140	biolink:NamedThing	presynaptic actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.	got7fsn_ti							dos	2017-06-09T18:34:19Z						biological_process											owl:Class	
GO:0032315	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043087	biolink:NamedThing	regulation of GTPase activity	Any process that modulates the rate of GTP hydrolysis by a GTPase.	got7fsn_ti	regulation of Ral GTPase activity|regulation of Cdc42 GTPase activity|regulation of Rap GTPase activity|regulation of Ran GTPase activity|regulation of Rac GTPase activity|regulation of Rab GTPase activity|regulation of ARF GTPase activity|regulation of Rho GTPase activity|regulation of Ras GTPase activity										GO:0032315|GO:0032313|GO:0032314|GO:0043088|GO:0032318|GO:0032319|GO:0032312|GO:0032317|GO:0032316			biological_process											owl:Class	
GO:0032054	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048748	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072477	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002386	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071804	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042036	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017138	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016956	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044279	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098783	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016597	biolink:NamedThing	amino acid binding	Binding to an amino acid, organic acids containing one or more amino substituents.	got7fsn_ti														molecular_function											owl:Class	
GO:0021857	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072416	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003735	biolink:NamedThing	structural constituent of ribosome	The action of a molecule that contributes to the structural integrity of the ribosome.	got7fsn_ti	ribosomal RNA|ribosomal protein				Note that this term may be used to annotate ribosomal RNAs as well as ribosomal proteins.						GO:0003739|GO:0003742|GO:0003736|GO:0003737|GO:0003740|GO:0003738|GO:0003741			molecular_function											owl:Class	
GO:0009241	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904834	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043832	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043358	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000505	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044263	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051690	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002741	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002720	biolink:NamedThing	positive regulation of cytokine production involved in immune response	Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.	got7fsn_ti	stimulation of cytokine production during immune response|positive regulation of cytokine biosynthetic process involved in immune response|positive regulation of cytokine secretion involved in immune response|activation of cytokine production during immune response|positive regulation of cytokine production during immune response|up regulation of cytokine production during immune response|up-regulation of cytokine production during immune response|upregulation of cytokine production during immune response										GO:0002744|GO:0002741			biological_process											owl:Class	
GO:0005843	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045371	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032737	biolink:NamedThing	positive regulation of interleukin-14 production	Any process that activates or increases the frequency, rate, or extent of interleukin-14 production.	got7fsn_ti	positive regulation of interleukin-14 biosynthetic process|up-regulation of interleukin-14 production|stimulation of interleukin-14 production|upregulation of interleukin-14 production|positive regulation of IL-14 production|activation of interleukin-14 production|up regulation of interleukin-14 production										GO:0045371			biological_process											owl:Class	
GO:0072691	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045846	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002717	biolink:NamedThing	positive regulation of natural killer cell mediated immunity	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.	got7fsn_ti	positive regulation of NK cell activity|upregulation of natural killer cell mediated immunity|up-regulation of natural killer cell mediated immunity|up regulation of natural killer cell mediated immunity|positive regulation of natural killer cell activity|activation of natural killer cell mediated immunity|stimulation of natural killer cell mediated immunity|positive regulation of NK cell mediated immunity										GO:0045846			biological_process											owl:Class	
GO:1902096	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044459	biolink:NamedThing	obsolete plasma membrane part	OBSOLETE. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005886				True				cellular_component											owl:Class	
GO:0090568	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:gocheck_do_not_manually_annotate	biolink:NamedThing			got7fsn_ti					Term not to be used for direct manual annotation																				owl:AnnotationProperty	
GO:0072401	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048124	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015238	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043119	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000490	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032321	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042963	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048123	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098959	biolink:NamedThing	retrograde dendritic transport of mitochondrion	The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse.	got7fsn_ti	retrograde dendrite transport of mitochondria													biological_process											owl:Class	
GOP:goslim_aspergillus	biolink:NamedThing			got7fsn_ti					Aspergillus GO slim																				owl:AnnotationProperty	
GO:0030113	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:goslim_mouse	biolink:NamedThing			got7fsn_ti					Mouse GO slim																				owl:AnnotationProperty	
GO:0098546	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061636	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009818	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:3176	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071862	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072542	biolink:NamedThing	protein phosphatase activator activity	Binds to and increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.	got7fsn_ti	protein phosphatase type 2A activator activity|protein phosphatase type 1 activator activity|protein phosphatase 2 activator activity						mah	2010-09-10T03:39:56Z			GO:0072543|GO:0071862			molecular_function											owl:Class	
GO:0051277	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001747	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001077	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000787	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904696	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071896	biolink:NamedThing	protein localization to adherens junction	Any process in which a protein is transported to, and/or maintained at the adherens junction.	got7fsn_ti	protein localization in cell-cell adherens junction|protein localisation to adherens junction|protein localisation in cell-cell adherens junction|protein localisation to cell-cell adherens junction|protein localization in adherens junction|protein localization to cell-cell adherens junction|protein localisation in adherens junction						mah	2010-09-14T04:03:27Z			GO:1904696			biological_process											owl:Class	
GO:0060733	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045527	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010861	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030375	biolink:NamedThing	obsolete thyroid hormone receptor coactivator activity	OBSOLETE. The function of a transcription cofactor that activates transcription in conjunction with a thyroid hormone-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.	got7fsn_ti	thyroid hormone receptor activator activity|thyroid hormone receptor co-activator activity				This term was obsoleted because it represented a gene product.					True	GO:0010861			molecular_function											owl:Class	
GO:0061717	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140142	biolink:NamedThing	nucleocytoplasmic carrier activity	Binding to and carrying a cargo between the nucleus and the cytoplasm by moving along with the cargo. The cargo can be either a RNA or a protein.	got7fsn_ti	nucleocytoplasmic importin/exportin activity|pre-miRNA transporter activity|miRNA transporter activity	https://github.com/geneontology/go-ontology/issues/17399|https://github.com/geneontology/go-ontology/issues/14336					pg	2017-12-06T13:40:40Z			GO:0090631|GO:0061717			molecular_function											owl:Class	
GO:0003763	biolink:NamedThing	obsolete chaperonin ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.	got7fsn_ti	chaperonin|chaperonin ATPase activity			GO:0016887	This term was made obsolete because it represents a class of gene products, and its definition incorporates process information.	GO:0006457				True	GO:0003766|GO:0003765|GO:0003764			molecular_function											owl:Class	
GO:0042266	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001141	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015237	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003740	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042237	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070011	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006946	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045280	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050576	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032519	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015678	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019189	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902519	biolink:NamedThing	response to docetaxel trihydrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.	got7fsn_ti	response to docetaxel				Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:44:04Z						biological_process											owl:Class	
GO:0003698	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016955	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034065	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048637	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072556	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006947	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:goslim_candida	biolink:NamedThing			got7fsn_ti					Candida GO slim																				owl:AnnotationProperty	
OIO:SubsetProperty	biolink:NamedThing	subset_property		got7fsn_ti																									owl:AnnotationProperty	
GO:0052529	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032852	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072457	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905419	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010261	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098998	biolink:NamedThing	extrinsic component of postsynaptic early endosome membrane	The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0052428	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042519	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042509	biolink:NamedThing	regulation of tyrosine phosphorylation of STAT protein	Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	got7fsn_ti	regulation of tyrosine phosphorylation of Stat6 protein|regulation of tyrosine phosphorylation of Stat2 protein|regulation of tyrosine phosphorylation of Stat7 protein|regulation of tyrosine phosphorylation of Stat4 protein|regulation of tyrosine phosphorylation of Stat3 protein|regulation of tyrosine phosphorylation of Stat5 protein|regulation of tyrosine phosphorylation of Stat1 protein										GO:0042525|GO:0042519|GO:0042522|GO:0042510|GO:0042528|GO:0042513|GO:0042516			biological_process											owl:Class	
NCBITaxon:4895	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052348	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000695	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075121	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0023033	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015781	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042260	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045377	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032739	biolink:NamedThing	positive regulation of interleukin-16 production	Any process that activates or increases the frequency, rate, or extent of interleukin-16 production.	got7fsn_ti	up regulation of interleukin-16 production|activation of interleukin-16 production|positive regulation of IL-16 production|upregulation of interleukin-16 production|stimulation of interleukin-16 production|positive regulation of interleukin-16 biosynthetic process|up-regulation of interleukin-16 production										GO:0045377			biological_process											owl:Class	
GO:0001166	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902947	biolink:NamedThing	regulation of tau-protein kinase activity	Any process that modulates the frequency, rate or extent of tau-protein kinase activity.	got7fsn_ti	regulation of [Tau protein] kinase activity|regulation of tau-protein kinase I activity|regulation of tau protein kinase activity|regulation of tau-tubulin kinase activity|regulation of TPK|regulation of STK31|regulation of TPK I|regulation of GSK|regulation of TPK II|regulation of CDK5/p23|regulation of glycogen synthase kinase-3beta activity|regulation of cdk5/p20|regulation of tau-protein kinase II activity|regulation of TTK|regulation of ATP:tau-protein O-phosphotransferase activity|regulation of protein tau kinase activity|regulation of tau kinase activity|regulation of brain protein kinase PK40erk activity						sjp	2014-05-02T08:43:27Z						biological_process											owl:Class	
GO:0032022	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150194	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150191	biolink:NamedThing	positive regulation of interleukin-32 production	Any process that activates or increases the frequency, rate or extent of interleukin-32 production.	got7fsn_ti	positive regulation of interleukin-32 biosynthetic process|positive regulation of interleukin-32 secretion						bc	2020-02-21T10:33:39Z			GO:0150194			biological_process											owl:Class	
GO:0016288	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003770	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008321	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005085	biolink:NamedThing	guanyl-nucleotide exchange factor activity	Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.	got7fsn_ti	Rho guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|Rho guanine nucleotide exchange factor|guanyl-nucleotide releasing factor|cAMP-dependent guanyl-nucleotide exchange factor activity|GDP-dissociation stimulator activity|Ran guanyl-nucleotide exchange factor activity|Rap guanyl-nucleotide exchange factor activity|GNRP|Rab guanyl-nucleotide exchange factor activity|Rac guanyl-nucleotide exchange factor activity|Sar guanyl-nucleotide exchange factor activity|GEF|Ral guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|GDS|guanyl-nucleotide release factor activity|RhoGEF	https://github.com/geneontology/go-ontology/issues/18749|https://github.com/geneontology/go-ontology/issues/18750									GO:0008433|GO:0005088|GO:0019839|GO:0005089|GO:0005086|GO:0016219|GO:0030676|GO:0017132|GO:0005087|GO:0008321|GO:0017034|GO:0017112|GO:0016220|GO:0005090	Reactome:R-HSA-9624845|Reactome:R-HSA-5623508|Reactome:R-HSA-5654413|Reactome:R-HSA-8850041|Reactome:R-HSA-5655241|Reactome:R-HSA-169904|Reactome:R-HSA-177945|Reactome:R-HSA-5654426|Reactome:R-HSA-2029451|Reactome:R-HSA-9665707|Reactome:R-HSA-5655347|Reactome:R-HSA-1225957|Reactome:R-HSA-170979|Reactome:R-HSA-8877612|Reactome:R-HSA-9607304|Reactome:R-HSA-8875568|Reactome:R-HSA-379048|Reactome:R-HSA-1168636|Reactome:R-HSA-186834|Reactome:R-HSA-3928651|Reactome:R-HSA-9640167|Reactome:R-HSA-418579|Reactome:R-HSA-9029158|Reactome:R-HSA-8876193|Reactome:R-HSA-399995|Reactome:R-HSA-6811429|Reactome:R-HSA-939265|Reactome:R-HSA-5694409|Reactome:R-HSA-8875318|Reactome:R-HSA-8877813|Reactome:R-HSA-8853307|Reactome:R-HSA-8877998|Reactome:R-HSA-418850|Reactome:R-HSA-8876616|Reactome:R-HSA-392195|Reactome:R-HSA-3928632|Reactome:R-HSA-419166|Reactome:R-HSA-210977|Reactome:R-HSA-8848618|Reactome:R-HSA-3928612|Reactome:R-HSA-389350|Reactome:R-HSA-2424477|Reactome:R-HSA-4093336|Reactome:R-HSA-5218850|Reactome:R-HSA-177938|Reactome:R-HSA-8877475|Reactome:R-HSA-8982637|Reactome:R-HSA-442273|Reactome:R-HSA-2029467|Reactome:R-HSA-416588|Reactome:R-HSA-8851899|Reactome:R-HSA-8851827|Reactome:R-HSA-3928592|Reactome:R-HSA-380073|Reactome:R-HSA-8876191|Reactome:R-HSA-109817|Reactome:R-HSA-3928633|Reactome:R-HSA-8877451|Reactome:R-HSA-9665404|Reactome:R-HSA-418856|Reactome:R-HSA-9665408|Reactome:R-HSA-1250463|Reactome:R-HSA-1250383|Reactome:R-HSA-5218839|Reactome:R-HSA-1250498|Reactome:R-HSA-2029445|Reactome:R-HSA-9660824|Reactome:R-HSA-416530|Reactome:R-HSA-9639286|Reactome:R-HSA-5623521|Reactome:R-HSA-5617816|Reactome:R-HSA-5637806|Reactome:R-HSA-2179407|Reactome:R-HSA-9670436|Reactome:R-HSA-109807|Reactome:R-HSA-5637808|Reactome:R-HSA-442314|Reactome:R-HSA-6807868|Reactome:R-HSA-5654402|Reactome:R-HSA-420883|Reactome:R-HSA-8964604|Reactome:R-HSA-749453|Reactome:R-HSA-9032067|Reactome:R-HSA-350769|Reactome:R-HSA-9672170|Reactome:R-HSA-392870|Reactome:R-HSA-6811414|Reactome:R-HSA-5654647|Reactome:R-HSA-5654618|Reactome:R-HSA-180687|Reactome:R-HSA-399938|Reactome:R-HSA-9666430|Reactome:R-HSA-203977|Reactome:R-HSA-5654392|Reactome:R-HSA-5655277|Reactome:R-HSA-1306972|Reactome:R-HSA-5654663|Reactome:R-HSA-156913|Reactome:R-HSA-9032798|Reactome:R-HSA-8876190|Reactome:R-HSA-2424476|Reactome:R-HSA-445064|Reactome:R-HSA-171026|Reactome:R-HSA-3928642|Reactome:R-HSA-5686071|Reactome:R-HSA-8876615|Reactome:R-HSA-114544|Reactome:R-HSA-9672163|Reactome:R-HSA-8877308|Reactome:R-HSA-8982640|Reactome:R-HSA-205039|Reactome:R-HSA-8875320|Reactome:R-HSA-5686318|Reactome:R-HSA-3965444|Reactome:R-HSA-392054|Reactome:R-HSA-3928628|Reactome:R-HSA-379044|Reactome:R-HSA-8877311|Reactome:R-HSA-2730840|Reactome:R-HSA-5672965|Reactome:R-HSA-9664991|Reactome:R-HSA-8877760|Reactome:R-HSA-8851877|Reactome:R-HSA-1433415|Reactome:R-HSA-442732|Reactome:R-HSA-825631|Reactome:R-HSA-9033292|Reactome:R-HSA-428917|Reactome:R-HSA-5654600|Reactome:R-HSA-5218829|Reactome:R-HSA-8876454|Reactome:R-HSA-428750|Reactome:R-HSA-9634418|Reactome:R-HSA-1433471|Reactome:R-HSA-428535|Reactome:R-HSA-8875591|Reactome:R-HSA-8876837|Reactome:R-HSA-751029|Reactome:R-HSA-9619803|Reactome:R-HSA-9703441|Reactome:R-HSA-9026891|Reactome:R-HSA-442291|Reactome:R-HSA-389348|Reactome:R-HSA-9666428|Reactome:R-HSA-194518|Reactome:R-HSA-2485180|Reactome:R-HSA-8876188|Reactome:R-HSA-354173|Reactome:R-HSA-1225951|Reactome:R-HSA-187746|Reactome:R-HSA-6811418|Reactome:R-HSA-5655326|Reactome:R-HSA-9665700|Reactome:R-HSA-9665009|Reactome:R-HSA-9695853|Reactome:R-HSA-194913		molecular_function											owl:Class	
GO:0052558	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008326	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052513	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016440	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048604	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072615	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061814	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000043	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036233	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903804	biolink:NamedThing	glycine import across plasma membrane	The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	glycine import|glycine import into cell						bf	2012-05-11T01:16:45Z			GO:0036233			biological_process											owl:Class	
GO:0045363	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032654	biolink:NamedThing	regulation of interleukin-11 production	Any process that modulates the frequency, rate, or extent of interleukin-11 production.	got7fsn_ti	regulation of IL-11 production|regulation of interleukin-11 biosynthetic process|regulation of interleukin-11 secretion										GO:0045363|GO:0150169			biological_process											owl:Class	
GO:0051810	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000509	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030967	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036288	biolink:NamedThing	response to ximelagatran	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-16T05:03:56Z						biological_process											owl:Class	
GO:0031180	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048414	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000366	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046427	biolink:NamedThing	positive regulation of receptor signaling pathway via JAK-STAT	Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.	got7fsn_ti	positive regulation of STAT protein nuclear translocation|positive regulation of STAT protein import into nucleus|stimulation of JAK-STAT cascade|activation of JAK-STAT cascade|up regulation of JAK-STAT cascade|up-regulation of JAK-STAT cascade|upregulation of JAK-STAT cascade										GO:2000366			biological_process											owl:Class	
GO:0044707	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033682	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052526	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043789	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990123	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900042	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032743	biolink:NamedThing	positive regulation of interleukin-2 production	Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.	got7fsn_ti	up-regulation of interleukin-2 production|upregulation of interleukin-2 production|activation of interleukin-2 production|stimulation of interleukin-2 production|positive regulation of interleukin-2 secretion|positive regulation of interleukin-2 biosynthetic process|up regulation of interleukin-2 production|positive regulation of IL-2 production										GO:0045086|GO:1900042			biological_process											owl:Class	
GO:0039538	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030028	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030231	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015585	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031184	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072454	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072412	biolink:NamedThing	obsolete detection of stimulus involved in mitotic cell cycle checkpoint	OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a mitotic cell cycle checkpoint.	got7fsn_ti	mitotic cell cycle G1/S checkpoint sensor mechanism|mitotic cell cycle checkpoint sensor mechanism|detection of stimulus involved in mitotic cell cycle G1/S checkpoint|sensing involved in mitotic cell cycle checkpoint|mitotic cell cycle checkpoint sensor process|sensing involved in mitotic cell cycle G1/S checkpoint|mitotic cell cycle G1/S checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:48:57Z		True	GO:0072454|GO:0072472			biological_process											owl:Class	
GO:0006841	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030606	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000134	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019110	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015831	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032844	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048676	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051809	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032947	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150162	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150159	biolink:NamedThing	negative regulation of interleukin-34 production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production.	got7fsn_ti	negative regulation of interleukin-34 biosynthetic process						bc	2020-01-06T16:31:12Z			GO:0150162			biological_process											owl:Class	
GO:0045388	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018382	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046768	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018372	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015682	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046954	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045032	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018055	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018018	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052306	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052265	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090467	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030605	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000370	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:28009	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005282	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905963	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051242	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008485	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044811	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018605	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045908	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090476	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015457	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045674	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044425	biolink:NamedThing	obsolete membrane part	OBSOLETE. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0016020				True				cellular_component											owl:Class	
NCBITaxon:3312	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003728	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033213	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015587	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035466	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052550	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0080055	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042513	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000442	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001718	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006822	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099064	biolink:NamedThing	integral component of postsynaptic endosome membrane	The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0090039	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034243	biolink:NamedThing	regulation of transcription elongation from RNA polymerase II promoter	Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.	got7fsn_ti	regulation of RNA elongation from RNA polymerase II promoter|regulation of gene-specific transcription elongation from RNA polymerase II promoter										GO:0090039			biological_process											owl:Class	
GO:0006916	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000983	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0055084	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052272	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030090	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002744	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046840	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017112	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007103	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031399	biolink:NamedThing	regulation of protein modification process	Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0006944	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022895	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018994	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051297	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015582	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031791	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0020029	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038050	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030025	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903957	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072519	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061505	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071229	biolink:NamedThing	cellular response to acid chemical	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.	got7fsn_ti	cellular response to oxoanion|cellular response to acid anion|cellular response to acid				This term should be used to describe a response to a specific acid as a chemical. E.g., if a cell were responding to glutamate, then the response would be glutamate-specific; the cell is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0071468 'cellular response to acidic pH' instead.		mah	2009-12-03T02:07:23Z						biological_process											owl:Class	
GO:0005361	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045531	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032671	biolink:NamedThing	regulation of interleukin-27 production	Any process that modulates the frequency, rate, or extent of interleukin-27 production.	got7fsn_ti	regulation of interleukin-27 biosynthetic process|regulation of IL-27 production|regulation of interleukin-27 synthesis|regulation of interleukin-27 formation										GO:0045531			biological_process											owl:Class	
GO:0047210	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900401	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030236	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001142	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098707	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051829	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009981	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015555	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901476	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048417	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001590	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044356	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140362	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017016	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045422	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032723	biolink:NamedThing	positive regulation of connective tissue growth factor production	Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production.	got7fsn_ti	up-regulation of connective tissue growth factor production|positive regulation of Fisp12 production|positive regulation of connective tissue growth factor biosynthetic process|activation of connective tissue growth factor production|positive regulation of hypertrophic chondrocyte-specific gene product 24 production|positive regulation of IGFBP8 production|positive regulation of Hcs24 production|stimulation of connective tissue growth factor production|positive regulation of CCN2 production|positive regulation of CTGF production|upregulation of connective tissue growth factor production|up regulation of connective tissue growth factor production										GO:0045422			biological_process											owl:Class	
GO:0045410	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032755	biolink:NamedThing	positive regulation of interleukin-6 production	Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.	got7fsn_ti	upregulation of interleukin-6 production|positive regulation of IL-6 production|positive regulation of interleukin-6 biosynthetic process|activation of interleukin-6 production|positive regulation of interleukin-6 secretion|stimulation of interleukin-6 production|up regulation of interleukin-6 production|up-regulation of interleukin-6 production										GO:2000778|GO:0045410			biological_process											owl:Class	
GO:0023032	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000396	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902470	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099516	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052549	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042687	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045421	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032683	biolink:NamedThing	negative regulation of connective tissue growth factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production.	got7fsn_ti	negative regulation of CTGF production|negative regulation of CCN2 production|inhibition of connective tissue growth factor production|negative regulation of Fisp12 production|negative regulation of connective tissue growth factor biosynthetic process|negative regulation of hypertrophic chondrocyte-specific gene product 24 production|negative regulation of Hcs24 production|downregulation of connective tissue growth factor production|down regulation of connective tissue growth factor production|negative regulation of IGFBP8 production|down-regulation of connective tissue growth factor production										GO:0045421			biological_process											owl:Class	
GO:0031971	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:4932	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904265	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036263	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044121	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072437	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051426	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090128	biolink:NamedThing	regulation of synapse maturation	Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.	got7fsn_ti							tb	2009-12-07T03:00:58Z						biological_process											owl:Class	
GO:0019735	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016534	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097483	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902591	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008262	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005049	biolink:NamedThing	nuclear export signal receptor activity	Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.	got7fsn_ti	exportin activity|importin-alpha export receptor activity|NES receptor|importin-alpha binding	https://github.com/geneontology/go-ontology/issues/14336									GO:0008262			molecular_function											owl:Class	
GO:0043106	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0020017	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0023013	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031075	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045401	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052059	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0023045	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030045	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031790	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048274	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030306	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030069	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052305	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052535	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016820	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903990	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017073	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:4896	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043118	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030483	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019167	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050707	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071956	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070526	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002390	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016452	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905806	biolink:NamedThing	regulation of synapse pruning	Any process that modulates the frequency, rate or extent of synapse pruning.	got7fsn_ti	regulation of synapse elimination|regulation of synapse removal|regulation of synapse disassembly|regulation of synapse clearance						tb	2017-01-11T22:03:15Z						biological_process											owl:Class	
GO:0061601	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048422	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:goslim_plant	biolink:NamedThing			got7fsn_ti					Plant GO slim																				owl:AnnotationProperty	
GO:0034984	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016548	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048606	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902449	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005554	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048862	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001903	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051713	biolink:NamedThing	negative regulation of cytolysis in other organism	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cytolysis of cells in another organism.	got7fsn_ti	downregulation of cytolysis of cells of another organism|inhibition of cytolysis of cells of another organism|down regulation of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another, non-host, organism|down-regulation of cytolysis of cells of another organism										GO:0001903			biological_process											owl:Class	
GO:0030503	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045418	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032718	biolink:NamedThing	negative regulation of interleukin-9 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production.	got7fsn_ti	inhibition of interleukin-9 production|negative regulation of IL-9 production|down regulation of interleukin-9 production|downregulation of interleukin-9 production|down-regulation of interleukin-9 production|negative regulation of interleukin-9 biosynthetic process										GO:0045418			biological_process											owl:Class	
GO:0033649	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098805	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004678	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009816	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032004	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009520	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006960	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098968	biolink:NamedThing	neurotransmitter receptor transport postsynaptic membrane to endosome	Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome.	got7fsn_ti														biological_process											owl:Class	
GO:0009285	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052302	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905743	biolink:NamedThing	calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration	Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration.	got7fsn_ti	mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration|calcium ion transmembrane import into mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration						dos	2016-12-06T10:53:17Z						biological_process											owl:Class	
GO:0044119	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016047	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031678	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032846	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019733	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016976	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051813	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016069	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019986	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031512	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035587	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102022	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990282	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902707	biolink:NamedThing	hexose catabolic process to ethanol	The chemical reactions and pathways resulting in the breakdown of hexose to ethanol.	got7fsn_ti	solventogenesis|hexose breakdown to ethanol|hexose degradation to ethanol|hexose catabolism to ethanol						tb	2014-02-19T21:33:08Z			GO:1990282			biological_process											owl:Class	
GO:0032146	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043359	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008101	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140554	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044153	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009613	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000667	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018840	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018987	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042486	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005961	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036442	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000189	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072462	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042604	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052070	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010532	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010579	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042737	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:241407	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099148	biolink:NamedThing	regulation of synaptic vesicle docking	Any process that modulates the frequency, rate or extent of synaptic vesicle docking.	got7fsn_ti							dos	2017-07-05T13:10:10Z						biological_process											owl:Class	
GO:0031792	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902538	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019952	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904209	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000343	biolink:NamedThing	positive regulation of chemokine (C-X-C motif) ligand 2 production	Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.	got7fsn_ti	positive regulation of chemokine (C-C motif) ligand 2 secretion|positive regulation of SCYB2 production|positive regulation of MIP2 production|positive regulation of MIP-2 production|positive regulation of CXCL2 production|positive regulation of CCL2 secretion						mah	2011-02-01T11:57:20Z			GO:1904209			biological_process											owl:Class	
GO:0098957	biolink:NamedThing	anterograde axonal transport of mitochondrion	The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.	got7fsn_ti	anterograde axon transport of mitochondria													biological_process											owl:Class	
GO:0009393	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015242	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031193	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005772	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902468	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032955	biolink:NamedThing	regulation of division septum assembly	Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	got7fsn_ti	regulation of division septum formation										GO:1902468|GO:1901138			biological_process											owl:Class	
GO:0000273	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015635	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004944	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044234	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016960	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075007	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904361	biolink:NamedThing	positive regulation of spore germination	Any process that activates or increases the frequency, rate or extent of spore germination.	got7fsn_ti	activation of spore germination|positive regulation of spore germination on or near host|up regulation of spore germination|upregulation of spore germination|up-regulation of spore germination						pf	2015-06-12T19:46:18Z			GO:0075007			biological_process											owl:Class	
GO:0008383	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990118	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050711	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032575	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042224	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052289	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008102	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072445	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072442	biolink:NamedThing	obsolete detection of stimulus involved in mitotic DNA replication checkpoint	OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a mitotic DNA replication checkpoint.	got7fsn_ti	S-M checkpoint sensor process|mitotic DNA replication checkpoint sensor process|mitotic DNA replication checkpoint sensor mechanism|detection of stimulus involved in S-M checkpoint|sensing involved in mitotic DNA replication checkpoint|sensing involved in S-M checkpoint|S-M checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T05:12:49Z		True	GO:0072445			biological_process											owl:Class	
GO:0072619	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072634	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002380	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008857	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903310	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001160	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000926	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015354	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903991	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032895	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035432	biolink:NamedThing	positive regulation of gluconate transmembrane transport	Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.	got7fsn_ti	stimulation of gluconate transport|positive regulation of gluconate membrane transport|up-regulation of gluconate transport|up regulation of gluconate transport|upregulation of gluconate transport|positive regulation of gluconate transport|activation of gluconate transport|induction of gluconate transport						bf	2010-04-08T10:39:58Z			GO:0032895			biological_process											owl:Class	
GO:0042035	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072608	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005099	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005096	biolink:NamedThing	GTPase activator activity	Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.	got7fsn_ti	GAP activity|Ran GAP activity|Sar GAP activity|ARF GTPase activator activity|Rap GTPase activator activity|Rho GAP activity|Ral GAP activity|ARF GAP activity|Rac GTPase activator activity|Sar GTPase activator activity|Rho GTPase activator activity|Rab GAP activity|RanGAP|Ras GTPase activator activity|Rab GTPase activator activity|Rac GAP activity|Ral GTPase activator activity|Rap GAP activity|Ras GAP activity|Ran GTPase activator activity				Note that the name Sar derives from 'secretion-associated, Ras-related'.						GO:0005100|GO:0005098|GO:0005101|GO:0008060|GO:0046582|GO:0017123|GO:0030675|GO:0005097|GO:0005099	Reactome:R-HSA-4093339|Reactome:R-HSA-428533|Reactome:R-HSA-392513|Reactome:R-HSA-9624893|Reactome:R-HSA-416546|Reactome:R-HSA-8985594|Reactome:R-HSA-416559|Reactome:R-HSA-194922|Reactome:R-HSA-399935|Reactome:R-HSA-5638007|Reactome:R-HSA-428522		molecular_function											owl:Class	
GO:0000359	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000599	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009993	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048433	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000157	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:4891	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019924	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042493	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990367	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015236	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042090	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015403	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044429	biolink:NamedThing	obsolete mitochondrial part	OBSOLETE. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.	got7fsn_ti	mitochondrial subcomponent|mitochondrion component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005739				True		NIF_Subcellular:sao666410040		cellular_component											owl:Class	
GO:0004887	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0120024	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019130	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052347	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032439	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050752	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032644	biolink:NamedThing	regulation of fractalkine production	Any process that modulates the frequency, rate, or extent of fractalkine production.	got7fsn_ti	regulation of CX3CL1 biosynthesis|regulation of CX3CL1 production|regulation of fractalkine biosynthetic process	https://github.com/geneontology/go-ontology/issues/19254									GO:0050752			biological_process											owl:Class	
GO:2000021	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045878	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045880	biolink:NamedThing	positive regulation of smoothened signaling pathway	Any process that activates or increases the frequency, rate or extent of smoothened signaling.	got7fsn_ti	positive regulation of smoothened by patched|stimulation of smoothened signaling pathway|positive regulation of hh signaling pathway|positive regulation of hedgehog signaling pathway|upregulation of smoothened signaling pathway|activation of smoothened signaling pathway|positive regulation of smoothened signalling pathway|up-regulation of smoothened signaling pathway|up regulation of smoothened signaling pathway|positive regulation of smoothened receptor activity by patched										GO:0045878			biological_process											owl:Class	
GO:0008621	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018821	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008491	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008490	biolink:NamedThing	arsenite secondary active transmembrane transporter activity	Enables the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	arsenite porter activity										GO:0008491			molecular_function											owl:Class	
GO:0061500	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006350	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052256	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006485	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001679	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030230	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072440	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044755	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098717	biolink:NamedThing	pantothenate import across plasma membrane	The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	pantothenate import|pantothenate import into cell						jl	2012-12-06T13:02:23Z			GO:0044755|GO:1901688			biological_process											owl:Class	
GO:0000371	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050791	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043140	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008461	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008916	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009405	biolink:NamedThing	obsolete pathogenesis	OBSOLETE. The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.	got7fsn_ti	virulence	https://github.com/geneontology/go-ontology/issues/11057			This term was obsoleted because it does not describe a single, normal biological process; rather it is the effect of an interaction between two organisms, under specific conditions.	GO:0052031|GO:0044003|GO:0052042				True				biological_process											owl:Class	
GO:0045546	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072611	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070364	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016978	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000218	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072644	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004472	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009484	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009482	biolink:NamedThing	obsolete ba3-type cytochrome c oxidase	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.	got7fsn_ti	ba3-type cytochrome c oxidase			GO:0004129	This term was made obsolete because it describes a class of gene products rather than a molecular function.					True	GO:0009484			molecular_function											owl:Class	
GO:0003751	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099083	biolink:NamedThing	retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission	Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0043623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008007	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044421	biolink:NamedThing	obsolete extracellular region part	OBSOLETE. Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.	got7fsn_ti	extracellular structure				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005576				True		NIF_Subcellular:sao9117790637		cellular_component											owl:Class	
GO:0016950	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046734	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019906	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052330	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005279	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031081	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016291	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:8782	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004004	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022621	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015206	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031373	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903274	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903277	biolink:NamedThing	negative regulation of sodium ion export across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane.	got7fsn_ti	down-regulation of sodium export|down-regulation of sodium ion export|down regulation of sodium export|down regulation of sodium ion export|down-regulation of sodium ion export from cell|negative regulation of sodium export|inhibition of sodium ion export from cell|negative regulation of sodium ion export|downregulation of sodium ion export from cell|inhibition of sodium export|down regulation of sodium ion export from cell|inhibition of sodium ion export|negative regulation of sodium ion export from cell|downregulation of sodium ion export|downregulation of sodium export						rl	2014-08-08T17:10:22Z			GO:1903274			biological_process											owl:Class	
GO:0019565	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051317	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051316	biolink:NamedThing	attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation	The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation.	got7fsn_ti	attachment of spindle microtubules to kinetochore during meiotic chromosome segregation|attachment of spindle microtubules to meiotic chromosome|attachment of spindle microtubules to kinetochore during meiosis										GO:0051317			biological_process											owl:Class	
GO:0051529	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008274	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035326	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032862	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016455	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016931	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006830	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035258	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001670	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004297	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001728	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007082	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902451	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018017	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004976	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000816	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:3378	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900393	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004886	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098699	biolink:NamedThing	structural constituent of presynaptic actin cytoskeleton	The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton.	got7fsn_ti							dos	2017-06-09T18:33:07Z						molecular_function											owl:Class	
GO:0048434	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052037	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017140	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008722	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0047737	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070010	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045381	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090477	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070751	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070755	biolink:NamedThing	negative regulation of interleukin-35 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.	got7fsn_ti	inhibition of interleukin-35 production|down regulation of interleukin-35 production|downregulation of interleukin-35 production|down-regulation of interleukin-35 production|negative regulation of interleukin-35 biosynthetic process|negative regulation of IL-35 production						mah	2009-06-23T01:34:54Z			GO:0070751			biological_process											owl:Class	
GO:0042524	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016687	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015359	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048116	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046955	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004580	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044244	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015523	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015518	biolink:NamedThing	arabinose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in).	got7fsn_ti	arabinose:hydrogen symporter activity|arabinose efflux permease activity|arabinose efflux transmembrane transporter activity										GO:0015523			molecular_function											owl:Class	
GO:0051487	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042114	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031239	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031237	biolink:NamedThing	intrinsic component of periplasmic side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that penetrate the periplasmic side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor.	got7fsn_ti	intrinsic to external leaflet of plasma membrane, in periplasmic space|intrinsic to periplasmic side of plasma membrane										GO:0031239			cellular_component											owl:Class	
GO:0009106	biolink:NamedThing	lipoate metabolic process	The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.	got7fsn_ti	lipoic acid metabolic process|lipoic acid metabolism|lipoate metabolism										GO:0000273			biological_process											owl:Class	
GO:1903414	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903988	biolink:NamedThing	iron ion export across plasma membrane	The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	ferrous iron export|ferrous iron export across plasma membrane|iron cation export|iron(2+) export				An example of this is mouse ferroportin (symbol Slc40a1, UniProtKB identifier: Q9JHI9).		rl	2014-09-03T13:01:37Z			GO:1903414			biological_process											owl:Class	
GO:0052090	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042241	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072450	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006375	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007046	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000789	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015405	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035468	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150035	biolink:NamedThing	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		bc	2018-04-17T13:56:34Z						biological_process											owl:Class	
GO:0072602	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015409	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035056	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006394	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905058	biolink:NamedThing	calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration	Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	got7fsn_ti	calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium levels						dos	2016-03-18T12:31:59Z						molecular_function											owl:Class	
GO:0044724	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051706	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031513	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032860	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032360	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0039660	biolink:NamedThing	structural constituent of virion	The action of a molecule that contributes to the structural integrity of a virion.	got7fsn_ti	viral matrix protein						bf	2013-07-22T16:43:41Z						molecular_function											owl:Class	
GO:0043037	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990345	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902452	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010699	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032779	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052275	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009053	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051374	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019737	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072456	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000665	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902765	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052293	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018088	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046750	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046760	biolink:NamedThing	viral budding from Golgi membrane	A viral budding that starts with formation of a membrane curvature in the host Golgi membrane.	got7fsn_ti	virus budding from Golgi membrane|virus budding from Golgi membrane by viral capsid envelopment|Golgi membrane viral budding|viral budding from Golgi membrane during viral capsid envelopment|Golgi membrane viral budding during viral capsid envelopment|virus budding from Golgi membrane during viral capsid envelopment|viral budding from Golgi membrane by viral capsid envelopment										GO:0046750|GO:0046763			biological_process											owl:Class	
GO:0045382	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005716	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031007	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016800	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035972	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035973	biolink:NamedThing	aggrephagy	Selective degradation of protein aggregates by macroautophagy.	got7fsn_ti							bf	2011-08-09T09:53:40Z			GO:0035972			biological_process											owl:Class	
GO:1990237	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902906	biolink:NamedThing	proteasome storage granule assembly	The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule.	got7fsn_ti	proteasome storage granule formation|PSG formation|PSG assembly|sequestration of proteasome core complex in proteasome storage granule	https://github.com/geneontology/go-ontology/issues/20458					di	2014-04-16T01:59:41Z			GO:1990237			biological_process											owl:Class	
GO:0051708	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098612	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052260	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150192	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060390	biolink:NamedThing	regulation of SMAD protein signal transduction	Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	got7fsn_ti	regulation of SMAD protein nuclear translocation|SMAD protein import into nucleus										GO:0007184			biological_process											owl:Class	
GO:0030571	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006745	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006557	biolink:NamedThing	S-adenosylmethioninamine biosynthetic process	The chemical reactions and pathways resulting in the formation of S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.	got7fsn_ti	S-adenosylmethioninamine formation|S-adenosylmethioninamine synthesis|S-adenosylmethioninamine anabolism|S-adenosylmethioninamine biosynthesis										GO:0006745			biological_process											owl:Class	
GO:0008844	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070632	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045399	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032672	biolink:NamedThing	regulation of interleukin-3 production	Any process that modulates the frequency, rate, or extent of interleukin-3 production.	got7fsn_ti	regulation of interleukin-3 biosynthetic process|regulation of IL-3 production										GO:0045399			biological_process											owl:Class	
GO:0001202	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000158	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052288	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034962	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009434	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000664	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007126	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075517	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042143	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035068	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052278	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052004	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990335	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015564	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902740	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032687	biolink:NamedThing	negative regulation of interferon-alpha production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.	got7fsn_ti	negative regulation of interferon-alpha secretion|down regulation of interferon-alpha production|negative regulation of interferon-alpha biosynthetic process|down-regulation of interferon-alpha production|downregulation of interferon-alpha production|inhibition of interferon-alpha production										GO:0045355|GO:1902740			biological_process											owl:Class	
GO:0075127	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003898	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140045	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061839	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000013	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000008	biolink:NamedThing	obsolete thioredoxin	OBSOLETE. A small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. Interacts with a broad range of proteins by a redox mechanism, based on the reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol.	got7fsn_ti	thioredoxin				This term was made obsolete because it represents gene products.	GO:0015036|GO:0003756				True	GO:0000013			molecular_function											owl:Class	
GO:0048111	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019012	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031200	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044415	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051244	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004841	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150037	biolink:NamedThing	regulation of calcium-dependent activation of synaptic vesicle fusion	Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion.	got7fsn_ti							bc	2018-04-18T12:47:38Z						biological_process											owl:Class	
GO:0044054	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004840	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034226	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004440	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018092	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018384	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005089	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050717	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042375	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043148	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901689	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905135	biolink:NamedThing	biotin import across plasma membrane	The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	biotin import into cell|biotin import						jl	2012-12-05T16:30:20Z			GO:1901689|GO:0044756			biological_process											owl:Class	
GO:0015512	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008339	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000042	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031742	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009283	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015246	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900865	biolink:NamedThing	chloroplast RNA modification	Any RNA modification that takes place in chloroplast.	got7fsn_ti	RNA editing in chloroplast						tb	2012-06-11T10:58:04Z						biological_process											owl:Class	
GO:0052152	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009262	biolink:NamedThing	deoxyribonucleotide metabolic process	The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	deoxyribonucleotide metabolism										GO:0009393|GO:0009122			biological_process											owl:Class	
GO:0006444	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017152	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030039	biolink:NamedThing	obsolete DNA unwinding factor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DNA unwinding factor			GO:0006268	This term was made obsolete because it does not represent a true molecular function.					True	GO:0017152			molecular_function											owl:Class	
GO:1904169	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072405	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043283	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036327	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043706	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045402	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003741	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001663	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003982	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070752	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016181	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048828	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001201	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005293	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019047	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050876	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097459	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008128	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018797	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042570	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019009	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0103024	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042111	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051644	biolink:NamedThing	plastid localization	Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	plastid localisation|establishment and maintenance of plastid localization													biological_process											owl:Class	
GO:0044400	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048276	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035389	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:147554	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072431	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031618	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033725	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071789	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001212	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018709	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052376	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071151	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051288	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051287	biolink:NamedThing	NAD binding	Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.	got7fsn_ti	NAD+ or NADH binding|NAD or NADH binding|nicotinamide adenine dinucleotide binding										GO:0051288			molecular_function											owl:Class	
GO:0032066	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035083	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030722	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007312	biolink:NamedThing	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification	The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.	got7fsn_ti	oocyte axis determination, establishment of position of nucleus|oocyte axis determination, establishment of localization of nucleus|establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|establishment of oocyte nucleus localization during oocyte axis determination|establishment of oocyte nucleus localization involved in oocyte dorsoventral axis specification|nucleus positioning in oocyte during oocyte axis determination|oocyte nucleus migration during oocyte axis specification|establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification|oocyte nuclear migration during oocyte axis determination|establishment of oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|oocyte nucleus positioning during oocyte axis determination|oocyte axis determination, oocyte nucleus migration|oocyte axis determination, oocyte nuclear migration|oocyte nucleus migration during oocyte axis determination|establishment of localization of oocyte nucleus during oocyte axis determination|oocyte axis determination, positioning of nucleus|oocyte axis determination, establishment of oocyte nucleus localization|establishment of oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification										GO:0048126|GO:0030722|GO:0048128|GO:0008102			biological_process											owl:Class	
GO:0051808	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902589	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001022	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043205	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0039681	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070261	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048129	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070749	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007145	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090157	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031178	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018347	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905077	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032700	biolink:NamedThing	negative regulation of interleukin-17 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.	got7fsn_ti	negative regulation of IL-17 production|downregulation of interleukin-17 production|down regulation of interleukin-17 production|negative regulation of CTLA-8 production|negative regulation of interleukin-17 biosynthetic process|inhibition of interleukin-17 production|negative regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion|negative regulation of interleukin-17 secretion										GO:0045379|GO:1905077			biological_process											owl:Class	
GO:0018806	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006332	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007152	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035534	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035531	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 6 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).	got7fsn_ti	regulation of chemokine (C-C motif) ligand 6 secretion|chemokine (C-C motif) ligand 6 secretion|regulation of CCL6 production						bf	2010-05-07T10:22:51Z			GO:0035534|GO:0035535			biological_process											owl:Class	
NCBITaxon:451866	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004091	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009565	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009844	biolink:NamedThing	obsolete germination	OBSOLETE. The physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.	got7fsn_ti	germination				This term was made obsolete because it is a grouping term without biological significance.					True	GO:0009565			biological_process											owl:Class	
GO:0051739	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018349	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042041	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031197	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018370	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009456	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008182	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035549	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050703	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045043	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005970	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005969	biolink:NamedThing	serine-pyruvate aminotransferase complex	An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate.	got7fsn_ti	serine-pyruvate aminotransferase, type 2B complex|serine-pyruvate aminotransferase, type 1 complex										GO:0005970			cellular_component											owl:Class	
GO:0010580	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033136	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044268	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030468	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044112	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045528	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032668	biolink:NamedThing	regulation of interleukin-24 production	Any process that modulates the frequency, rate, or extent of interleukin-24 production.	got7fsn_ti	regulation of IL-24 production|regulation of interleukin-24 biosynthetic process										GO:0045528			biological_process											owl:Class	
GO:0042569	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048552	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901677	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010537	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004011	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008089	biolink:NamedThing	anterograde axonal transport	The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.	got7fsn_ti	anterograde axon cargo transport													biological_process											owl:Class	
GO:0048187	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001107	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010382	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900174	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003353	biolink:NamedThing	positive regulation of cilium movement	Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.	got7fsn_ti	positive regulation of flagellum movement|positive regulation of microtubule-based flagellum movement|positive regulation of flagellar movement				Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-12-03T10:16:10Z			GO:1900174			biological_process											owl:Class	
GO:0046743	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035638	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901042	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905589	biolink:NamedThing	positive regulation of L-arginine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane.	got7fsn_ti	positive regulation of L-arginine import|upregulation of L-arginine import|up-regulation of L-arginine import into cell|upregulation of L-arginine import into cell|activation of L-arginine import|activation of L-arginine uptake|up regulation of L-arginine import|positive regulation of L-arginine uptake|up regulation of L-arginine uptake|activation of L-arginine import across plasma membrane|up-regulation of L-arginine uptake|upregulation of L-arginine uptake|positive regulation of L-arginine import into cell|up-regulation of L-arginine import|activation of L-arginine import into cell						al	2012-06-25T12:27:24Z			GO:1901042|GO:1902828			biological_process											owl:Class	
GO:0007226	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990288	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902698	biolink:NamedThing	pentose catabolic process to butyrate	The chemical reactions and pathways resulting in the breakdown of pentose to butyrate.	got7fsn_ti	pentose catabolism to butyrate|pentose breakdown to butyrate|pentose degradation to butyrate|acidogenesis						tb	2014-02-19T18:28:28Z			GO:1990288			biological_process											owl:Class	
GO:0016116	biolink:NamedThing	carotenoid metabolic process	The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.	got7fsn_ti	carotenoid metabolism													biological_process											owl:Class	
GO:1902454	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033676	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044801	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032858	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098668	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097623	biolink:NamedThing	potassium ion export across plasma membrane	The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	potassium ion export|potassium ion export from cell|potassium export across plasma membrane|potassium export	https://github.com/geneontology/go-ontology/issues/14265					pr	2009-12-16T11:10:45Z			GO:0098668|GO:0071435			biological_process											owl:Class	
GO:0060564	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019494	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010133	biolink:NamedThing	proline catabolic process to glutamate	The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate.	got7fsn_ti	proline breakdown to glutamate|proline oxidation|proline degradation to glutamate										GO:0019494	MetaCyc:PWY-4561|MetaCyc:PROUT-PWY		biological_process											owl:Class	
GO:0030384	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048739	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002506	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030247	biolink:NamedThing	polysaccharide binding	Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	got7fsn_ti	polysaccharide assembly with MHC class II protein complex										GO:0002506			molecular_function											owl:Class	
GO:0034261	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006674	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006673	biolink:NamedThing	inositol phosphoceramide metabolic process	The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group.	got7fsn_ti	inositolphosphoceramide metabolism|inositol phosphorylceramide metabolism|inositol phosphorylceramide metabolic process										GO:0006674			biological_process											owl:Class	
GO:0019963	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071992	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022820	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010536	biolink:NamedThing	positive regulation of activation of Janus kinase activity	Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.	got7fsn_ti	positive regulation of activation of JAK protein|positive regulation of activation of JAK2 kinase activity|positive regulation of activation of JAK1 protein|positive regulation of tyrosine phosphorylation of JAK1 protein|positive regulation of tyrosine phosphorylation of JAK protein|positive regulation of activation of JAK1 kinase activity|positive regulation of activation of JAK2 protein|positive regulation of tyrosine phosphorylation of JAK2 protein										GO:0010535|GO:0010537			biological_process											owl:Class	
GO:0085028	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000318	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045534	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032710	biolink:NamedThing	negative regulation of interleukin-26 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production.	got7fsn_ti	down-regulation of interleukin-26 production|inhibition of interleukin-26 production|down regulation of interleukin-26 production|downregulation of interleukin-26 production|negative regulation of IL-26 production|negative regulation of interleukin-26 biosynthetic process										GO:0045534			biological_process											owl:Class	
GO:0045373	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006594	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099132	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090456	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090517	biolink:NamedThing	L-lysine transmembrane import into vacuole	The directed movement of L-lysine into the vacuole across the vacuolar membrane.	got7fsn_ti	lysine transmembrane import into vacuole|vacuolar lysine import						tb	2012-09-24T14:12:46Z			GO:0090456			biological_process											owl:Class	
GO:0051832	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000046	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071780	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052285	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990337	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043389	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010388	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003745	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001624	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004959	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016292	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017104	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019591	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051157	biolink:NamedThing	arabitol catabolic process	The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.	got7fsn_ti	arabitol catabolism|arabitol utilization|arabitol degradation|arabitol breakdown										GO:0019591			biological_process											owl:Class	
GO:0043109	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048430	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030013	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010551	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003076	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016932	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098748	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008642	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052166	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902377	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099037	biolink:NamedThing	anchored component of presynaptic endosome membrane	The component of the presynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0042829	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008639	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051834	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016450	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043191	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004688	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051811	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045536	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046420	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045675	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042518	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904439	biolink:NamedThing	negative regulation of iron ion import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane.	got7fsn_ti	negative regulation of ferrous iron import into cell|down regulation of ferrous iron import across plasma membrane|negative regulation of ferrous iron import across plasma membrane|down-regulation of ferrous iron import across plasma membrane|down regulation of ferrous ion import into cell|downregulation of ferrous iron import across plasma membrane|inhibition of ferrous ion import into cell|inhibition of ferrous iron import across plasma membrane|downregulation of ferrous ion import into cell|down-regulation of ferrous ion import into cell|negative regulation of ferrous ion import into cell						rl	2015-07-06T13:49:58Z			GO:1903990			biological_process											owl:Class	
GO:0018374	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051852	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990945	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072403	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072394	biolink:NamedThing	obsolete detection of stimulus involved in cell cycle checkpoint	OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a cell cycle checkpoint.	got7fsn_ti	detection of stimulus involved in G2/M transition checkpoint|G2/M transition checkpoint sensor mechanism|detection of stimulus involved in G1/S transition checkpoint|cell cycle checkpoint sensor mechanism|G1/S transition checkpoint sensor process|sensing involved in G2/M transition checkpoint|G1/S transition checkpoint sensor mechanism|sensing involved in G1/S transition checkpoint|cell cycle checkpoint sensor process|sensing involved in cell cycle checkpoint|G2/M transition checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T02:55:56Z		True	GO:0072403|GO:0072406			biological_process											owl:Class	
GO:0042347	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901223	biolink:NamedThing	negative regulation of NIK/NF-kappaB signaling	Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.	got7fsn_ti	down-regulation of NIK/NF-kappaB cascade|down regulation of p52-dependent NF-kappaB signaling|inhibition of noncanonical NF-kappaB signaling|downregulation of p52-dependent NF-kappaB signaling|down-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|downregulation of NIK/NF-kappaB cascade|negative regulation of NF-kappaB import into nucleus|down-regulation of non-canonical NF-KB signaling|inhibition of p52-dependent NF-kappaB signaling|negative regulation of noncanonical NF-kappaB signaling|down regulation of noncanonical NF-kappaB signaling|inhibition of NIK/NF-kappaB cascade|inhibition of non-canonical NF-KB signaling|down-regulation of p52-dependent NF-kappaB signaling|negative regulation of non-canonical NF-KB signaling|down-regulation of noncanonical NF-kappaB signaling|down regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|negative regulation of NIK/NF-kappaB cascade|down regulation of NIK/NF-kappaB cascade|negative regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|downregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|downregulation of non-canonical NF-KB signaling|downregulation of noncanonical NF-kappaB signaling|negative regulation of p52-dependent NF-kappaB signaling|inhibition of noncanonical nuclear factor kappaB (NF-kappaB) pathway|down regulation of non-canonical NF-KB signaling						hjd	2012-08-06T20:27:39Z			GO:0042347			biological_process											owl:Class	
GO:0045395	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007457	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043166	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048595	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001038	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035536	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036347	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009857	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042871	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042222	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006443	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010533	biolink:NamedThing	regulation of activation of Janus kinase activity	Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.	got7fsn_ti	regulation of activation of JAK1 protein|regulation of activation of JAK2 kinase activity|regulation of activation of JAK1 kinase activity|regulation of tyrosine phosphorylation of JAK2 protein|regulation of activation of JAK2 protein|regulation of tyrosine phosphorylation of JAK1 protein|regulation of tyrosine phosphorylation of JAK protein|regulation of activation of JAK protein										GO:0010532|GO:0010534			biological_process											owl:Class	
GO:0031199	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075145	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004296	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045359	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001589	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046531	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008394	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010281	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043080	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017123	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035104	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052279	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990290	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052539	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019223	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018087	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004696	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075060	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000503	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075061	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006330	biolink:NamedThing	obsolete single-stranded DNA binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	single-stranded DNA binding			GO:0003697	This term was made obsolete because it represents a molecular function and not a biological process.					True	GO:0006332|GO:0006331			biological_process											owl:Class	
GO:0099061	biolink:NamedThing	integral component of postsynaptic density membrane	The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0051578	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030044	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030040	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017155	biolink:NamedThing	obsolete sodium:hydrogen antiporter regulator activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	sodium:proton antiporter regulator|sodium:hydrogen antiporter regulator activity				This term was made obsolete because it represents a biological process.					True	GO:0030040			molecular_function											owl:Class	
GO:0046605	biolink:NamedThing	regulation of centrosome cycle	Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.	got7fsn_ti														biological_process											owl:Class	
GO:0036144	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070627	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901549	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006899	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098693	biolink:NamedThing	regulation of synaptic vesicle cycle	Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.	got7fsn_ti							dos	2017-03-21T16:06:48Z						biological_process											owl:Class	
GO:0045084	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022892	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090469	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098713	biolink:NamedThing	leucine import across plasma membrane	The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	leucine import into cell|L-leucine import into cell						mah	2013-06-12T12:27:47Z			GO:1990122			biological_process											owl:Class	
GO:1903802	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903273	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150171	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032734	biolink:NamedThing	positive regulation of interleukin-11 production	Any process that activates or increases the frequency, rate, or extent of interleukin-11 production.	got7fsn_ti	stimulation of interleukin-11 production|up-regulation of interleukin-11 production|positive regulation of interleukin-11 secretion|upregulation of interleukin-11 production|up regulation of interleukin-11 production|activation of interleukin-11 production|positive regulation of IL-11 production|positive regulation of interleukin-11 biosynthetic process										GO:0045365|GO:0150171			biological_process											owl:Class	
GO:0001611	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032853	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004684	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015268	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090702	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015037	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044744	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045075	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032655	biolink:NamedThing	regulation of interleukin-12 production	Any process that modulates the frequency, rate, or extent of interleukin-12 production.	got7fsn_ti	regulation of NKSF production|regulation of CLMF production|regulation of interleukin-12 biosynthetic process|regulation of IL-12 production|regulation of interleukin-12 secretion										GO:0045075|GO:2001182			biological_process											owl:Class	
GO:0016928	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031190	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051528	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008647	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009621	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006008	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043735	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902419	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004870	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098844	biolink:NamedThing	postsynaptic endocytic zone membrane	The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone.  This region of membrane is associated with stable clathrin puncta.	got7fsn_ti														cellular_component											owl:Class	
GO:0045394	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032706	biolink:NamedThing	negative regulation of interleukin-22 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production.	got7fsn_ti	down regulation of interleukin-22 production|down-regulation of interleukin-22 production|inhibition of interleukin-22 production|downregulation of interleukin-22 production|negative regulation of IL-22 production|negative regulation of interleukin-22 biosynthetic process										GO:0045394			biological_process											owl:Class	
GO:0005333	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102016	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015413	biolink:NamedThing	ABC-type nickel transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in).	got7fsn_ti	nickel transporting ATPase activity|nickel ABC transporter|nickel porter activity|ATPase-coupled nickel transmembrane transporter activity|ATP-dependent nickel transmembrane transporter activity|nickel ABC transporter activity|nickel-transporting ATPase activity										GO:0102016	MetaCyc:3.6.3.24-RXN|EC:7.2.2.11|MetaCyc:ABC-20-RXN|RHEA:15557		molecular_function											owl:Class	
GO:0047226	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150193	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018843	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000496	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008325	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048131	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031181	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010687	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016948	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001213	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010107	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045396	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032667	biolink:NamedThing	regulation of interleukin-23 production	Any process that modulates the frequency, rate, or extent of interleukin-23 production.	got7fsn_ti	regulation of IL-23 biosynthetic process|regulation of interleukin-23 biosynthetic process|regulation of interleukin-23 biosynthesis|regulation of IL-23 production|regulation of interleukin-23 anabolism|regulation of interleukin-23 formation|regulation of interleukin-23 synthesis										GO:0045396			biological_process											owl:Class	
GO:0043347	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048413	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072616	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050724	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016958	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052824	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003771	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003767	biolink:NamedThing	obsolete co-chaperone activity	OBSOLETE. Co-chaperones are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperones by themselves do not possess chaperone activity.	got7fsn_ti	co-chaperone activity				This term was made obsolete because it represents a class of gene products rather than a molecular function.	GO:0044183|GO:0051087|GO:0006457				True	GO:0003769|GO:0003770|GO:0003771|GO:0003768			molecular_function											owl:Class	
GO:0015610	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015430	biolink:NamedThing	ABC-type glycerol-3-phosphate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in).	got7fsn_ti	ATPase-coupled glycerol-3-phosphate transmembrane transporter activity|ATPase-coupled glycerol-2-phosphate transmembrane transporter activity|glycerol-3-phosphate ABC transporter|glycerol phosphate-importing ATPase activity|ATP-dependent glycerol-2-phosphate transmembrane transporter activity|glycerol-2-phosphate-transporting ATPase activity|glycerol-phosphate porter activity|ABC-type glycerol 3-phosphate transporter|glycerol-3-phosphate-transporting ATPase	https://github.com/geneontology/go-ontology/issues/17164									GO:0015610|GO:0070812	MetaCyc:3.6.3.20-RXN|RHEA:21668|EC:7.6.2.10		molecular_function											owl:Class	
GO:0072486	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045083	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052189	biolink:NamedThing	obsolete modulation by symbiont of defense-related host cell wall callose deposition	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of defense-related host callose deposition|modulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|modulation by organism of defense-related callose deposition of other organism involved in symbiotic interaction				This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052285|GO:0052090|GO:0052310			biological_process											owl:Class	
GO:0048126	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003739	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001023	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006320	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150123	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035140	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017068	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043074	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150127	biolink:NamedThing	regulation of interleukin-33 production	Any process that modulates the frequency, rate or extent of interleukin-33 production.	got7fsn_ti	regulation of interleukin-33 secretion|regulation of interleukin-33 biosynthetic process						bc	2019-12-03T05:54:03Z			GO:0150123|GO:0150130			biological_process											owl:Class	
GO:0001013	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035055	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048024	biolink:NamedThing	regulation of mRNA splicing, via spliceosome	Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.	got7fsn_ti	regulation of nuclear mRNA splicing via U2-type spliceosome|regulation of nuclear mRNA splicing, via spliceosome|regulation of pre-mRNA splicing										GO:0035055			biological_process											owl:Class	
GO:0008640	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032854	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990925	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001052	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075501	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001159	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003758	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030872	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990759	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0103095	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005349	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015604	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904454	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042681	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051227	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043019	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046913	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018714	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048415	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019041	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002216	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000169	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005162	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015458	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:554915	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070363	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033680	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009540	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015590	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000441	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016809	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034712	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033224	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005748	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099146	biolink:NamedThing	intrinsic component of postsynaptic density membrane	The component of the postsynaptic density membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to postsynaptic specialization membrane						dos	2017-07-05T10:43:24Z						cellular_component											owl:Class	
GO:0006093	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004562	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022891	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071157	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051441	biolink:NamedThing	obsolete positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle.	got7fsn_ti	meiotic anaphase promoting complex activation|activation of ubiquitin ligase activity of anaphase promoting complex during meiotic cell cycle|meiotic APC activator|meiotic anaphase promoting complex activator|meiotic anaphase-promoting complex activator|APC activation during meiotic cell cycle|activation of anaphase-promoting complex activity involved in meiotic cell cycle|anaphase promoting complex activation during meiotic cell cycle|meiotic SCF complex activator|meiotic ubiquitin ligase activator|activation of ubiquitin ligase activity of anaphase-promoting complex during meiotic cell cycle|anaphase-promoting complex activation during meiotic cell cycle|activation of ubiquitin ligase activity of APC during meiotic cell cycle|up regulation of ubiquitin ligase activity during meiotic cell cycle|positive regulation of ubiquitin-protein ligase activity during meiotic cell cycle|activation of ubiquitin ligase activity during meiotic cell cycle|stimulation of ubiquitin ligase activity during meiotic cell cycle|positive regulation of ubiquitin ligase activity during meiotic cell cycle|up-regulation of ubiquitin ligase activity during meiotic cell cycle|activation of anaphase-promoting complex activity during meiotic cell cycle|upregulation of ubiquitin ligase activity during meiotic cell cycle|meiotic APC activation	https://github.com/geneontology/go-ontology/issues/15196			This term was obsoleted because it should be captured as a GO-CAM model.					True	GO:0051487			biological_process											owl:Class	
GO:0015460	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048043	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038052	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903806	biolink:NamedThing	L-isoleucine import across plasma membrane	The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-isoleucine import into cell|isoleucine import|L-isoleucine import						tb	2012-10-01T11:10:51Z			GO:0090477|GO:0090476			biological_process											owl:Class	
GO:0004872	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001137	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001135	biolink:NamedThing	obsolete RNA polymerase II transcription regulator recruiting activity	OBSOLETE. The function of binding to an RNA polymerase II (RNAP II) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.	got7fsn_ti	transcription factor activity, RNA polymerase II transcription factor recruiting|transcription factor activity, TFIIE-class transcription factor recruiting|RNA polymerase II transcription factor recruiting transcription factor activity|RNA polymerase II transcription factor recruiting activity|transcription factor activity, TFIIF-class transcription factor recruiting|transcription factor activity, TFIIH-class transcription factor recruiting|TFIIF-class transcription factor recruiting transcription factor activity|TFIIE-class transcription factor recruiting transcription factor activity|TFIIH-class transcription factor recruiting transcription factor activity	https://github.com/geneontology/go-ontology/issues/18561|https://github.com/geneontology/go-ontology/issues/15795		GO:0003712	The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'.		krc	2011-01-20T05:13:12Z		True	GO:0001136|GO:0001137|GO:0001138			molecular_function											owl:Class	
GO:0090247	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090248	biolink:NamedThing	cell migration involved in somitogenic axis elongation	Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.	got7fsn_ti	cell motility involved in somitogenic axis elongation	https://github.com/geneontology/go-annotation/issues/2040					tb	2010-01-22T11:13:59Z			GO:0090247			biological_process											owl:Class	
GO:0052309	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019967	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000129	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075143	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004811	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000357	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090197	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032722	biolink:NamedThing	positive regulation of chemokine production	Any process that activates or increases the frequency, rate, or extent of chemokine production.	got7fsn_ti	up regulation of chemokine production|stimulation of chemokine production|positive regulation of chemokine secretion|upregulation of chemokine production|up-regulation of chemokine production|positive regulation of chemokine biosynthetic process|activation of chemokine production						tb	2009-12-18T11:28:00Z			GO:0045080|GO:0090197			biological_process											owl:Class	
GO:0035085	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035532	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 6 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).	got7fsn_ti	negative regulation of CCL6 production|negative regulation of chemokine (C-C motif) ligand 6 secretion						bf	2010-05-07T10:23:40Z			GO:0035536			biological_process											owl:Class	
GO:0017167	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018318	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102078	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902467	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032673	biolink:NamedThing	regulation of interleukin-4 production	Any process that modulates the frequency, rate, or extent of interleukin-4 production.	got7fsn_ti	regulation of IL-4 production|regulation of interleukin-4 secretion|regulation of interleukin-4 biosynthetic process										GO:0045402|GO:0150133			biological_process											owl:Class	
GO:0102908	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015418	biolink:NamedThing	ABC-type quaternary ammonium compound transporting activity	Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H(+) + phosphate + quaternary ammonium(in).	got7fsn_ti	ATP-dependent quaternary-ammonium compound transmembrane transporting activity|quaternary-ammonium-compound ABC transporter|glycine betaine/proline porter activity|quaternary-ammonium-compound-transporting ATPase activity|quaternary amine uptake transporter activity|quaternary-amine-transporting ATPase activity|ATPase-coupled quaternary ammonium compound transmembrane transporting activity|quarternary amine transporter activity										GO:0102908	RHEA:11036|EC:7.6.2.9|MetaCyc:RXN-8638|MetaCyc:3.6.3.32-RXN		molecular_function											owl:Class	
GO:0045215	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008969	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052537	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044705	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048424	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051662	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006872	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052300	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052161	biolink:NamedThing	obsolete modulation by symbiont of defense-related host cell wall thickening	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|modulation by organism of host defensive cell wall thickening				This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052300			biological_process											owl:Class	
GO:0006010	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051156	biolink:NamedThing	glucose 6-phosphate metabolic process	The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.	got7fsn_ti	glucose 6-phosphate utilization|glucose 6-phosphate metabolism										GO:0006010			biological_process											owl:Class	
GO:0016967	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015388	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902949	biolink:NamedThing	positive regulation of tau-protein kinase activity	Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity.	got7fsn_ti	up regulation of brain protein kinase PK40erk activity|activation of STK31|up regulation of tau-protein kinase II activity|upregulation of tau-protein kinase I activity|positive regulation of TTK|positive regulation of glycogen synthase kinase-3beta activity|up-regulation of tau-protein kinase I activity|activation of tau-protein kinase I activity|positive regulation of tau-protein kinase I activity|up-regulation of TTK|positive regulation of protein tau kinase activity|upregulation of GSK|upregulation of tau-protein kinase II activity|positive regulation of cdk5/p20|up-regulation of TPK I|upregulation of TPK|upregulation of [Tau protein] kinase activity|up regulation of TTK|up-regulation of TPK|positive regulation of STK31|positive regulation of tau-protein kinase II activity|activation of tau kinase activity|up-regulation of STK31|positive regulation of TPK I|positive regulation of tau protein kinase activity|activation of CDK5/p23|activation of protein tau kinase activity|activation of [Tau protein] kinase activity|upregulation of tau-tubulin kinase activity|positive regulation of TPK II|activation of tau-protein kinase activity|up-regulation of glycogen synthase kinase-3beta activity|upregulation of glycogen synthase kinase-3beta activity|activation of cdk5/p20|positive regulation of TPK|up regulation of tau kinase activity|activation of TTK|activation of glycogen synthase kinase-3beta activity|up-regulation of tau-protein kinase II activity|activation of brain protein kinase PK40erk activity|up regulation of protein tau kinase activity|up-regulation of tau-tubulin kinase activity|up regulation of STK31|up-regulation of [Tau protein] kinase activity|up regulation of cdk5/p20|up regulation of tau protein kinase activity|activation of GSK|upregulation of STK31|upregulation of TPK I|upregulation of tau protein kinase activity|upregulation of tau kinase activity|upregulation of CDK5/p23|up-regulation of tau protein kinase activity|up-regulation of GSK|up-regulation of TPK II|up regulation of TPK I|upregulation of protein tau kinase activity|activation of tau-protein kinase II activity|positive regulation of brain protein kinase PK40erk activity|up-regulation of protein tau kinase activity|upregulation of brain protein kinase PK40erk activity|up-regulation of tau-protein kinase activity|activation of TPK II|activation of TPK I|positive regulation of GSK|activation of tau-tubulin kinase activity|activation of tau protein kinase activity|up regulation of tau-protein kinase I activity|positive regulation of [Tau protein] kinase activity|upregulation of tau-protein kinase activity|positive regulation of tau kinase activity|up-regulation of tau kinase activity|upregulation of TPK II|upregulation of cdk5/p20|positive regulation of CDK5/p23|up regulation of CDK5/p23|up regulation of [Tau protein] kinase activity|up regulation of tau-tubulin kinase activity|activation of TPK|up-regulation of cdk5/p20|up-regulation of CDK5/p23|up regulation of TPK|up-regulation of brain protein kinase PK40erk activity|upregulation of TTK|up regulation of tau-protein kinase activity|up regulation of TPK II|up regulation of glycogen synthase kinase-3beta activity|up regulation of GSK|positive regulation of tau-tubulin kinase activity						sjp	2014-05-02T08:43:38Z						biological_process											owl:Class	
GO:0030607	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098893	biolink:NamedThing	extrinsic component of postsynaptic endocytic zone	The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0016276	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018223	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015852	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006863	biolink:NamedThing	purine nucleobase transport	The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	purine base transport|purine transport|purine base transmembrane transport|purine transmembrane transport										GO:0015852			biological_process											owl:Class	
GO:0018536	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010552	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030764	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099553	biolink:NamedThing	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:1902450	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000065	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098935	biolink:NamedThing	dendritic transport	The directed movement of organelles or molecules along microtubules in dendrites.	got7fsn_ti	dendrite cargo transport													biological_process											owl:Class	
GO:0045946	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900475	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072640	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099065	biolink:NamedThing	integral component of spine apparatus membrane	The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0071790	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005380	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903458	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005032	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042477	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006455	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018373	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019691	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006258	biolink:NamedThing	UDP-glucose catabolic process	The chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-glucose catabolism|UDP-glucose conversion|UDP-glucose degradation|UDP-glucose breakdown										GO:0019691			biological_process											owl:Class	
GO:0039515	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042506	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003744	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032518	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045555	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032719	biolink:NamedThing	negative regulation of TRAIL production	Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production.	got7fsn_ti	inhibition of TRAIL production|downregulation of TRAIL production|negative regulation of TRAIL biosynthetic process|down-regulation of TRAIL production|down regulation of TRAIL production										GO:0045555			biological_process											owl:Class	
GO:0006151	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102316	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002743	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002719	biolink:NamedThing	negative regulation of cytokine production involved in immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.	got7fsn_ti	negative regulation of cytokine production during immune response|down-regulation of cytokine production during immune response|negative regulation of cytokine secretion involved in immune response|downregulation of cytokine production during immune response|inhibition of cytokine production during immune response|negative regulation of cytokine biosynthetic process involved in immune response|down regulation of cytokine production during immune response										GO:0002743|GO:0002740			biological_process											owl:Class	
GO:0045393	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900165	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902303	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016225	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001638	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004093	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990614	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045016	biolink:NamedThing	mitochondrial magnesium ion transmembrane transport	The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti	mitochondrial magnesium ion transport						mcc	2015-01-21T17:44:38Z			GO:1990614			biological_process											owl:Class	
GO:0001200	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044428	biolink:NamedThing	obsolete nuclear part	OBSOLETE. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.	got7fsn_ti	nucleus component|nuclear subcomponent				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005634				True		NIF_Subcellular:sao1499850686		cellular_component											owl:Class	
GO:0008778	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043285	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016686	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035690	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018090	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904468	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032720	biolink:NamedThing	negative regulation of tumor necrosis factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.	got7fsn_ti	negative regulation of tumor necrosis factor biosynthetic process|negative regulation TNF-alpha production|inhibition of tumor necrosis factor production|down regulation of tumor necrosis factor production|inhibition of cachectin production|negative regulation tumor necrosis factor-alpha production|negative regulation of tumor necrosis factor secretion|down-regulation of tumor necrosis factor production|negative regulation TNF production|downregulation of tumor necrosis factor production				Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').		sl	2015-07-09T19:50:08Z			GO:0042536|GO:1904468			biological_process											owl:Class	
GO:0010554	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000071	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005033	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052413	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030146	biolink:NamedThing	obsolete diuresis	OBSOLETE. The process of renal water excretion.	got7fsn_ti	positive regulation of renal water excretion|diuresis|renal water excretion				This term was made obsolete because its definition was inaccurate.	GO:0035810				True	GO:0003076	Wikipedia:Diuresis		biological_process											owl:Class	
GO:0005498	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051837	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008003	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046674	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043725	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052045	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043072	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005676	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044452	biolink:NamedThing	obsolete nucleolar part	OBSOLETE. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis.	got7fsn_ti	nucleolus component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005730				True				cellular_component											owl:Class	
GO:0042504	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075601	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060881	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034769	biolink:NamedThing	basement membrane disassembly	The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.	got7fsn_ti	basal lamina disassembly				Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer.		dph	2009-08-13T11:27:24Z			GO:0060881			biological_process											owl:Class	
GO:0003287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903275	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015589	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032317	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048117	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046650	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032728	biolink:NamedThing	positive regulation of interferon-beta production	Any process that activates or increases the frequency, rate, or extent of interferon-beta production.	got7fsn_ti	positive regulation of IFN-beta production|upregulation of interferon-beta production|up-regulation of interferon-beta production|stimulation of interferon-beta production|up regulation of interferon-beta production|positive regulation of interferon-beta biosynthetic process|positive regulation of interferon-beta secretion|activation of interferon-beta production										GO:0045359|GO:0035549			biological_process											owl:Class	
GO:0015163	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016547	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097521	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045524	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009928	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042534	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032680	biolink:NamedThing	regulation of tumor necrosis factor production	Any process that modulates the frequency, rate or extent of tumor necrosis factor production.	got7fsn_ti	regulation of tumor necrosis factor-alpha production|regulation of tumor necrosis factor biosynthetic process|regulation of TNF production|regulation of TNF-alpha production|regulation of cachectin production|regulation of tumor necrosis factor secretion				Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').		sl	2015-07-09T19:50:02Z			GO:1904467|GO:0042534			biological_process											owl:Class	
GO:0052397	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042508	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005855	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034047	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990291	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046731	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048068	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042239	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001214	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072443	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008105	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031454	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005329	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001009	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001644	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001075	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901240	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051023	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030102	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005807	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033753	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072601	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035467	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009105	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018728	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043775	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072372	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032754	biolink:NamedThing	positive regulation of interleukin-5 production	Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.	got7fsn_ti	positive regulation of interleukin-5 secretion|positive regulation of interleukin-5 biosynthetic process|upregulation of interleukin-5 production|up-regulation of interleukin-5 production|stimulation of interleukin-5 production|activation of interleukin-5 production|positive regulation of IL-5 production|up regulation of interleukin-5 production										GO:0045407|GO:2000664			biological_process											owl:Class	
GO:0099189	biolink:NamedThing	postsynaptic spectrin-associated cytoskeleton	The portion of the spectrin-associated cytoskeleton contained within the postsynapse.	got7fsn_ti							dos	2017-12-20T15:29:09Z						cellular_component											owl:Class	
GO:0090198	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032682	biolink:NamedThing	negative regulation of chemokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production.	got7fsn_ti	inhibition of chemokine production|downregulation of chemokine production|down regulation of chemokine production|negative regulation of chemokine secretion|down-regulation of chemokine production|negative regulation of chemokine biosynthetic process							2009-12-18T11:28:00Z			GO:0045079|GO:0090198			biological_process											owl:Class	
GO:0020012	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015873	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032857	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042155	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008348	biolink:NamedThing	negative regulation of antimicrobial humoral response	Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response.	got7fsn_ti	inhibition of antimicrobial humoral response|down-regulation of antimicrobial humoral response|down regulation of antimicrobial humoral response|downregulation of antimicrobial humoral response|attenuation of antimicrobial humoral response										GO:0042155|GO:0042154			biological_process											owl:Class	
GO:0090040	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901690	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015579	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015497	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006834	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990163	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043926	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050713	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032691	biolink:NamedThing	negative regulation of interleukin-1 beta production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.	got7fsn_ti	negative regulation of IL-1 beta production|negative regulation of interleukin-1 beta biosynthetic process|inhibition of interleukin-1 beta production|downregulation of interleukin-1 beta production|down regulation of interleukin-1 beta production|negative regulation of interleukin-1 beta secretion|down-regulation of interleukin-1 beta production										GO:0050713|GO:0050724			biological_process											owl:Class	
GO:0008122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044746	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050754	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030615	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050875	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990707	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048410	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001224	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015329	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015495	biolink:NamedThing	gamma-aminobutyric acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).	got7fsn_ti	4-aminobutanoate:proton symporter activity|gamma-aminobutyric acid permease activity|gamma-aminobutyric acid:hydrogen symporter activity|GABA:proton symporter activity|4-aminobutanoate:hydrogen symporter activity|4-aminobutyrate:proton symporter activity|4-aminobutyrate:hydrogen symporter activity|GABA:hydrogen symporter activity				See also the molecular function term 'neurotransmitter transporter activity ; GO:0005326'.						GO:0015329|GO:0005331	Reactome:R-HSA-428625		molecular_function											owl:Class	
GO:0032191	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900455	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060256	biolink:NamedThing	regulation of flocculation	Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.	got7fsn_ti	regulation of flocculation via cell wall protein-carbohydrate interaction						dgf	2012-05-01T05:03:32Z			GO:1900455			biological_process											owl:Class	
GO:0018354	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903261	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016745	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097689	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006243	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046036	biolink:NamedThing	CTP metabolic process	The chemical reactions and pathways involving CTP, cytidine triphosphate.	got7fsn_ti	CTP metabolism|CTP deamination										GO:0006243			biological_process											owl:Class	
GO:2001181	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052276	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005913	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061490	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098708	biolink:NamedThing	glucose import across plasma membrane	The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	high affinity glucose import|glucose import into cell						al	2012-12-06T14:54:07Z			GO:1990821|GO:0061490			biological_process											owl:Class	
GO:0042460	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048404	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044055	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002374	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004710	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070750	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043206	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902578	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051471	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042917	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075125	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008596	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030472	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042312	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033587	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072609	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052254	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045425	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016904	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075059	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904805	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042535	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032760	biolink:NamedThing	positive regulation of tumor necrosis factor production	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production.	got7fsn_ti	positive regulation of TNF-alpha production|positive regulation of TNF production|upregulation of tumor necrosis factor production|positive regulation of TNF secretion|positive regulation of tumor necrosis factor biosynthetic process|positive regulation of tumor necrosis factor formation|positive regulation of tumor necrosis factor secretion|activation of tumor necrosis factor production|up regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor biosynthesis|positive regulation of tumor necrosis factor-alpha production|stimulation of tumor necrosis factor production|up-regulation of tumor necrosis factor production|positive regulation of cachectin secretion				Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').		sl	2015-07-09T19:50:14Z			GO:0042535|GO:1904469			biological_process											owl:Class	
GO:0097404	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098720	biolink:NamedThing	succinate import across plasma membrane	The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	succinate import into cell						pr	2012-10-29T11:17:44Z			GO:0097404			biological_process											owl:Class	
GO:0098602	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051313	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004597	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008027	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015501	biolink:NamedThing	glutamate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).	got7fsn_ti	sodium/excitatory glutamate cotransporter activity|sodium/excitatory glutamate symporter activity										GO:0008027	RHEA:29031		molecular_function											owl:Class	
GO:0043360	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003907	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045372	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032658	biolink:NamedThing	regulation of interleukin-15 production	Any process that modulates the frequency, rate, or extent of interleukin-15 production.	got7fsn_ti	regulation of IL-15 production|regulation of interleukin-15 biosynthetic process										GO:0045372			biological_process											owl:Class	
GO:0005296	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005578	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0080063	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902409	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045378	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032660	biolink:NamedThing	regulation of interleukin-17 production	Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.	got7fsn_ti	regulation of CTLA-8 production|regulation of IL-17 production|regulation of interleukin-17 biosynthetic process|regulation of interleukin-17 secretion|regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion										GO:0045378|GO:1905076			biological_process											owl:Class	
GO:0006442	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008368	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051636	biolink:NamedThing	obsolete Gram-negative bacterial cell surface binding	OBSOLETE. Binding to a component on the surface of a Gram-negative bacterial cell.	got7fsn_ti	Gram-negative bacterium binding|binding to Gram-negative bacterium|Gram-negative bacterium cell surface binding|Gram-negative bacterial cell surface binding|Gram-negative bacterial binding				This term was made obsolete because it is an unnecessary grouping term and was causing confusion.	GO:0050829|GO:0003823				True	GO:0008368			molecular_function											owl:Class	
GO:0008590	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099114	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0065006	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002137	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903309	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905268	biolink:NamedThing	negative regulation of chromatin organization	Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization.	got7fsn_ti	negative regulation of chromatin organisation|inhibition of chromatin organisation|down-regulation of chromatin organization|inhibition of establishment or maintenance of chromatin architecture|downregulation of chromatin organization|down regulation of chromatin organisation|downregulation of establishment or maintenance of chromatin architecture|negative regulation of establishment or maintenance of chromatin architecture|downregulation of chromatin organisation|inhibition of chromatin organization|down-regulation of chromatin organisation|down regulation of chromatin organization|down regulation of establishment or maintenance of chromatin architecture|down-regulation of establishment or maintenance of chromatin architecture|negative regulation of chromatin modification						pr	2016-06-15T20:14:47Z			GO:1903309			biological_process											owl:Class	
GO:0005306	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043753	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008501	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015569	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017066	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008731	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004182	biolink:NamedThing	obsolete carboxypeptidase A activity	OBSOLETE. Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid. Little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.	got7fsn_ti	tissue carboxypeptidase A|carboxypolypeptidase activity|pancreatic carboxypeptidase A|carboxypeptidase A activity			GO:0004181	This term was made obsolete because it represents a gene product.					True	GO:0008731			molecular_function											owl:Class	
GO:0042528	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048591	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052561	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044213	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015999	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000980	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016003	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019734	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902665	biolink:NamedThing	response to isobutanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus.	got7fsn_ti	response to 2-methylpropan-1-ol|process resulting in tolerance to isobutanol										GO:1990337			biological_process											owl:Class	
GO:0000997	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032856	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034600	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001226	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042257	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045252	biolink:NamedThing	oxoglutarate dehydrogenase complex	A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).	got7fsn_ti	dihydrolipoamide S-succinyltransferase complex				See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.									cellular_component											owl:Class	
GO:0035413	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090263	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway	Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	got7fsn_ti	positive regulation of catenin import into nucleus|positive regulation of Wnt receptor signaling pathway through beta-catenin|positive regulation of catenin protein nuclear translocation|positive regulation of canonical Wnt receptor signaling pathway|positive regulation of canonical Wnt-activated signaling pathway|positive regulation of canonical Wnt receptor signalling pathway						tb	2010-02-03T04:32:16Z			GO:0035413			biological_process											owl:Class	
GO:0042484	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001185	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048175	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032605	biolink:NamedThing	hepatocyte growth factor production	The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	HGF production|hepatocyte growth factor biosynthetic process|scatter factor production										GO:0048175			biological_process											owl:Class	
GO:0102192	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030358	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075123	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003125	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045392	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006514	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030065	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034459	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000037	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072650	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0047752	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010175	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044810	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044783	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0012503	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015510	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000125	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043016	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002742	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051576	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016660	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052932	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004330	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140249	biolink:NamedThing	protein catabolic process at postsynapse	The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/204			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:25:04Z						biological_process											owl:Class	
GO:0030138	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008279	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016451	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015688	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045539	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015463	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050827	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046749	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007067	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098951	biolink:NamedThing	intrinsic component of postsynaptic recycling endosome membrane	The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to postsynaptic recycling endosome membrane													cellular_component											owl:Class	
GO:0052423	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018239	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0080087	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150169	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048747	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052299	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0020034	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046699	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035535	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031189	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042434	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071779	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061745	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008629	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007582	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045390	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0055132	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018986	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0040001	biolink:NamedThing	establishment of mitotic spindle localization	The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.	got7fsn_ti	mitotic spindle positioning|spindle positioning during mitosis|mitotic spindle positioning or orientation|mitotic spindle positioning and orientation|spindle positioning involved in mitotic cell cycle|establishment of mitotic spindle localisation										GO:0030610|GO:0018986|GO:0030606|GO:0030608|GO:0030605			biological_process											owl:Class	
GO:0044455	biolink:NamedThing	obsolete mitochondrial membrane part	OBSOLETE. Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0031966				True				cellular_component											owl:Class	
GO:0036231	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019193	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046728	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016968	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052370	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071841	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004770	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048231	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075006	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003996	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902715	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006467	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005336	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016537	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052060	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004220	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010386	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008468	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019839	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090142	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002166	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015508	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044212	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072358	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902431	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098721	biolink:NamedThing	uracil import across plasma membrane	The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	uracil import into cell						tb	2013-09-27T17:54:23Z			GO:1902431			biological_process											owl:Class	
GO:0032894	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035431	biolink:NamedThing	negative regulation of gluconate transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.	got7fsn_ti	down-regulation of gluconate transport|down regulation of gluconate transport|inhibition of gluconate transport|negative regulation of gluconate membrane transport|downregulation of gluconate transport|negative regulation of gluconate transport						bf	2010-04-08T10:39:08Z			GO:0032894			biological_process											owl:Class	
GO:0016568	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044710	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052405	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009592	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005090	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016178	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902067	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098741	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030898	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:systematic_synonym	biolink:NamedThing	Systematic synonym		got7fsn_ti																									owl:AnnotationProperty	
OIO:SynonymTypeProperty	biolink:NamedThing	synonym_type_property		got7fsn_ti																									owl:AnnotationProperty	
GO:0072632	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045366	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032656	biolink:NamedThing	regulation of interleukin-13 production	Any process that modulates the frequency, rate, or extent of interleukin-13 production.	got7fsn_ti	regulation of interleukin-13 biosynthetic process|regulation of IL-13 production|regulation of interleukin-13 secretion										GO:0045366|GO:2000665			biological_process											owl:Class	
GO:0016954	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901237	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048419	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001071	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033589	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017079	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004002	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042087	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072446	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016193	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032503	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048176	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032646	biolink:NamedThing	regulation of hepatocyte growth factor production	Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production.	got7fsn_ti	regulation of hepatocyte growth factor biosynthetic process|regulation of HGF production|regulation of scatter factor production										GO:0048176			biological_process											owl:Class	
GO:0000040	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150131	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015490	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043872	biolink:NamedThing	lysine:cadaverine antiporter activity	Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out).	got7fsn_ti	lysine/cadaverine antiporter activity|cadaverine:lysine antiporter activity|lysine-cadaverine antiporter activity|cadaverine transmembrane transporter activity										GO:0015497|GO:0015490			molecular_function											owl:Class	
GO:0035057	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004406	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044431	biolink:NamedThing	obsolete Golgi apparatus part	OBSOLETE. Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.	got7fsn_ti	Golgi component|Golgi subcomponent				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005794				True		NIF_Subcellular:sao624292949		cellular_component											owl:Class	
GO:0005959	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003766	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150154	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005348	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006342	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043690	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015978	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045441	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072654	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001668	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045367	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001585	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060248	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015404	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032522	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033669	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052151	biolink:NamedThing	positive regulation by symbiont of host apoptotic process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of host apoptotic programmed cell death|activation by symbiont of host apoptosis|up-regulation by organism of host apoptotic programmed cell death|upregulation by symbiont of host apoptosis|activation by organism of host apoptosis|stimulation by symbiont of host apoptosis|upregulation by organism of host apoptotic programmed cell death|positive regulation by symbiont of host apoptosis|up regulation by organism of host apoptotic programmed cell death|up regulation by symbiont of host apoptosis|up-regulation by symbiont of host apoptosis|positive regulation by organism of host apoptotic programmed cell death|activation by organism of host apoptotic programmed cell death|induction by symbiont of host apoptosis				Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'positive regulation of apoptosis ; GO:0043065'.						GO:0052030|GO:0033669			biological_process											owl:Class	
GO:0018319	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004943	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046407	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052459	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015588	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000790	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045166	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052061	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015580	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016190	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043348	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019014	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099007	biolink:NamedThing	extrinsic component of presynaptic endosome membrane	The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:1901259	biolink:NamedThing	chloroplast rRNA processing	Any rRNA processing that takes place in chloroplast.	got7fsn_ti							tb	2012-08-10T17:43:19Z						biological_process											owl:Class	
GO:0070812	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004094	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052253	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052510	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904440	biolink:NamedThing	positive regulation of iron ion import across plasma membrane	Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane.	got7fsn_ti	activation of ferrous ion import into cell|upregulation of ferrous iron import across plasma membrane|upregulation of ferrous ion import into cell|up-regulation of ferrous ion import into cell|up regulation of ferrous ion import into cell|activation of ferrous iron import across plasma membrane|up-regulation of ferrous iron import across plasma membrane|up regulation of ferrous iron import across plasma membrane|positive regulation of ferrous iron import across plasma membrane|positive regulation of ferrous iron import into cell|positive regulation of ferrous ion import into cell						rl	2015-07-06T13:50:04Z			GO:1903991			biological_process											owl:Class	
GO:0043439	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016081	biolink:NamedThing	synaptic vesicle docking	The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component.  Synaptic vesicle tethering is the first step in this process.	got7fsn_ti	synaptic vesicle docking during exocytosis|synaptic vesicle docking involved in exocytosis				Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015).									biological_process											owl:Class	
GO:0048110	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015285	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032893	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051530	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902700	biolink:NamedThing	pentose catabolic process to butan-1-ol	The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol.	got7fsn_ti	pentose catabolism to butan-1-ol|solventogenesis|pentose catabolic process to 1-butanol|pentose degradation to butan-1-ol|pentose catabolic process to butanol|pentose breakdown to butan-1-ol						tb	2014-02-19T18:28:47Z			GO:1990290			biological_process											owl:Class	
GO:0050880	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006691	biolink:NamedThing	leukotriene metabolic process	The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.	got7fsn_ti	leukotriene metabolism													biological_process											owl:Class	
GO:0005644	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031980	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008555	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015725	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045288	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048416	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990307	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098636	biolink:NamedThing	protein complex involved in cell adhesion	Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.	got7fsn_ti	cell adhesion complex										GO:1990307			cellular_component											owl:Class	
GO:0030462	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009817	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004606	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008060	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019581	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019392	biolink:NamedThing	glucarate metabolic process	The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate.	got7fsn_ti	glucarate metabolism										GO:0019581			biological_process											owl:Class	
GO:0080174	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036142	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016228	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052297	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0023034	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044446	biolink:NamedThing	obsolete intracellular organelle part	OBSOLETE. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0043229				True				cellular_component											owl:Class	
GO:0001199	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072606	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007452	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050489	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035547	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032648	biolink:NamedThing	regulation of interferon-beta production	Any process that modulates the frequency, rate, or extent of interferon-beta production.	got7fsn_ti	regulation of interferon-beta secretion|regulation of IFN-beta production|regulation of interferon-beta biosynthetic process										GO:0045357|GO:0035547			biological_process											owl:Class	
GO:0000780	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030453	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000358	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034566	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150149	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001613	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070838	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008644	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045414	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032677	biolink:NamedThing	regulation of interleukin-8 production	Any process that modulates the frequency, rate, or extent of interleukin-8 production.	got7fsn_ti	regulation of interleukin-8 secretion|regulation of IL-8 production|regulation of interleukin-8 biosynthetic process										GO:0045414|GO:2000482			biological_process											owl:Class	
GO:0048005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098918	biolink:NamedThing	structural constituent of synapse	The action of a molecule that contributes to the structural integrity of a synapse.	got7fsn_ti														molecular_function											owl:Class	
GO:0001130	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002818	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071147	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030630	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044235	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070615	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000081	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052268	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043437	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019605	biolink:NamedThing	butyrate metabolic process	The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.	got7fsn_ti	butyric acid metabolic process|butyric acid metabolism|butanoic acid metabolic process|butyrate metabolism|butanoic acid metabolism										GO:0043437			biological_process											owl:Class	
GO:0051375	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007372	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030529	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903757	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034401	biolink:NamedThing	obsolete chromatin organization involved in regulation of transcription	OBSOLETE. Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter by histone modification|up-regulation of transcription from RNA polymerase II promoter by histone modification|regulation of transcription from RNA polymerase II promoter, global by histone modification|positive regulation of transcription from Pol II promoter by histone modification|up regulation of transcription from RNA polymerase II promoter by histone modification|regulation of global transcription from Pol II promoter by histone modification|activation of transcription from RNA polymerase II promoter by histone modification|positive regulation of global transcription from Pol II promoter by histone modification|upregulation of global transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from RNA polymerase II promoter, global by histone modification|regulation of transcription by chromatin organisation|stimulation of global transcription from RNA polymerase II promoter by histone modification|regulation of transcription from Pol II promoter by histone modification|stimulation of transcription from RNA polymerase II promoter by histone modification|up regulation of global transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from RNA polymerase II promoter by histone modification|upregulation of transcription from RNA polymerase II promoter by histone modification|positive regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|regulation of transcription by chromatin organization|regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|activation of global transcription from RNA polymerase II promoter by histone modification|establishment or maintenance of chromatin architecture during transcription|up-regulation of global transcription from RNA polymerase II promoter by histone modification	https://github.com/geneontology/go-ontology/issues/22041			This term was obsoleted because these it was redundant with other terms: heterochromatin assembly and regulation of gene expression, epigenetic.		rl	2014-12-18T14:56:16Z		True	GO:1903756|GO:1903757			biological_process											owl:Class	
GO:0050381	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990510	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072625	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052291	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000728	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008026	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072453	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010805	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905008	biolink:NamedThing	regulation of L-lysine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-lysine import into cell.	got7fsn_ti	regulation of lysine import|regulation of lysine uptake|regulation of L-lysine import into cell						sl	2016-03-02T00:15:49Z			GO:0010805			biological_process											owl:Class	
GO:0052273	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016140	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070924	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052258	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031202	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005932	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902534	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008434	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006322	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097349	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046515	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904208	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000342	biolink:NamedThing	negative regulation of chemokine (C-X-C motif) ligand 2 production	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.	got7fsn_ti	negative regulation of MIP-2 production|negative regulation of chemokine (C-C motif) ligand 2 secretion|inhibition of chemokine (C-C motif) ligand 2 secretion|negative regulation of SCYB2 production|inhibition of CCL2 secretion|negative regulation of MIP2 production|negative regulation of CXCL2 production						mah	2011-02-01T11:57:17Z			GO:1904208			biological_process											owl:Class	
GO:0061747	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006365	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044404	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008562	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030525	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036282	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008799	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045424	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032685	biolink:NamedThing	negative regulation of granulocyte macrophage colony-stimulating factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.	got7fsn_ti	negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|inhibition of granulocyte macrophage colony-stimulating factor production|down-regulation of granulocyte macrophage colony-stimulating factor production|negative regulation of granulocyte macrophage colony stimulating factor production|negative regulation of GM-CSF production|downregulation of granulocyte macrophage colony-stimulating factor production|down regulation of granulocyte macrophage colony-stimulating factor production										GO:0045424			biological_process											owl:Class	
GO:0050721	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032650	biolink:NamedThing	regulation of interleukin-1 alpha production	Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production.	got7fsn_ti	regulation of interleukin-1 alpha biosynthetic process|regulation of interleukin-1 alpha secretion|regulation of IL-1 alpha production										GO:0050705|GO:0050721			biological_process											owl:Class	
GO:1900871	biolink:NamedThing	chloroplast mRNA modification	The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti	chloroplast mRNA editing|mRNA editing in chloroplast						dhl	2012-06-12T06:13:58Z						biological_process											owl:Class	
GO:0072643	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006763	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097406	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009814	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150124	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034960	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006870	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008272	biolink:NamedThing	sulfate transport	The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	sulphate transport										GO:0006870			biological_process											owl:Class	
GO:0060246	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:go/go-base.owl	biolink:NamedThing	Gene Ontology	The Gene Ontology (GO) provides a framework and set of concepts for describing the functions of gene products from all organisms.	got7fsn_ti									gene_ontology				1.2					http://creativecommons.org/licenses/by/4.0/							owl:Ontology	2021-09-01
OBO:go/releases/2021-09-01/go-base.owl	biolink:NamedThing			got7fsn_ti																										
GO:2000778	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052632	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046732	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016337	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070890	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043566	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000498	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019190	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052307	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048155	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032715	biolink:NamedThing	negative regulation of interleukin-6 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.	got7fsn_ti	downregulation of interleukin-6 production|down regulation of interleukin-6 production|inhibition of interleukin-6 production|negative regulation of interleukin-6 biosynthetic process|negative regulation of IL-6 production|negative regulation of interleukin-6 secretion|down-regulation of interleukin-6 production										GO:0045409|GO:1900165			biological_process											owl:Class	
GO:0048411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005379	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990975	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050755	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042516	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045537	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006136	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048218	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008505	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032320	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001204	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045279	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031575	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036328	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016526	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042061	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004101	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099097	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008739	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018225	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070604	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032704	biolink:NamedThing	negative regulation of interleukin-20 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production.	got7fsn_ti	downregulation of interleukin-20 production|negative regulation of interleukin-20 biosynthetic process|negative regulation of IL-20 production|inhibition of interleukin-20 production|down regulation of interleukin-20 production|down-regulation of interleukin-20 production										GO:0045388			biological_process											owl:Class	
GO:0099067	biolink:NamedThing	integral component of presynaptic endosome membrane	The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0000924	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042319	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000251	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042261	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052445	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015065	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045030	biolink:NamedThing	G protein-coupled UTP receptor activity	Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP.	got7fsn_ti	purinoceptor type U|UTP-activated nucleotide receptor activity|uridine nucleotide receptor activity										GO:0015065			molecular_function											owl:Class	
GO:0045525	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007324	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044261	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032735	biolink:NamedThing	positive regulation of interleukin-12 production	Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.	got7fsn_ti	stimulation of interleukin-12 production|activation of interleukin-12 production|positive regulation of CLMF production|positive regulation of interleukin-12 biosynthetic process|positive regulation of interleukin-12 secretion|positive regulation of IL-12 production|up-regulation of interleukin-12 production|positive regulation of NKSF production|up regulation of interleukin-12 production|upregulation of interleukin-12 production										GO:2001184|GO:0045084			biological_process											owl:Class	
GO:0004785	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070015	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990903	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061495	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019818	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:5782	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048230	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016991	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000168	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900476	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048751	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000944	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034448	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043356	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005285	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OIO:hasExactSynonym	biolink:NamedThing	has_exact_synonym		got7fsn_ti																									owl:AnnotationProperty	
GO:0044125	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045074	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044438	biolink:NamedThing	obsolete microbody part	OBSOLETE. Any constituent part of a microbody, a cytoplasmic organelle, spherical or oval in shape, that is bounded by a single membrane and contains oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0042579				True				cellular_component											owl:Class	
GO:1902293	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043044	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006818	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052179	biolink:NamedThing	obsolete metabolism by symbiont of host cell wall pectin	OBSOLETE. The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction				This term was obsoleted because it represents a molecular function.					True	GO:0052413			biological_process											owl:Class	
GO:0030012	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098839	biolink:NamedThing	postsynaptic density membrane	The membrane component of the postsynaptic density. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.	got7fsn_ti														cellular_component											owl:Class	
GO:0008185	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016770	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005386	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099163	biolink:NamedThing	synaptic signaling by nitric oxide	Cell-cell signaling to or from a synapse, mediated by nitric oxide.	got7fsn_ti														biological_process											owl:Class	
GO:0004537	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042830	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019943	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070491	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048431	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000666	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090302	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031662	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010971	biolink:NamedThing	positive regulation of G2/M transition of mitotic cell cycle	Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.	got7fsn_ti	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle|positive regulation of mitotic entry						tb	2009-06-01T10:16:34Z			GO:0031662			biological_process											owl:Class	
GO:0019138	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050726	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032730	biolink:NamedThing	positive regulation of interleukin-1 alpha production	Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production.	got7fsn_ti	stimulation of interleukin-1 alpha production|up regulation of interleukin-1 alpha production|upregulation of interleukin-1 alpha production|activation of interleukin-1 alpha production|positive regulation of interleukin-1 alpha secretion|positive regulation of IL-1 alpha production|up-regulation of interleukin-1 alpha production|positive regulation of interleukin-1 alpha biosynthetic process										GO:0050726|GO:0050717			biological_process											owl:Class	
GO:0070756	biolink:NamedThing	positive regulation of interleukin-35 production	Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.	got7fsn_ti	stimulation of interleukin-35 production|positive regulation of interleukin-35 biosynthetic process|activation of interleukin-35 production|positive regulation of IL-35 production|up regulation of interleukin-35 production|upregulation of interleukin-35 production|up-regulation of interleukin-35 production						mah	2009-06-23T01:39:45Z			GO:0070752			biological_process											owl:Class	
GO:0045397	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000365	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046426	biolink:NamedThing	negative regulation of receptor signaling pathway via JAK-STAT	Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.	got7fsn_ti	negative regulation of STAT protein import into nucleus|downregulation of JAK-STAT cascade|down-regulation of JAK-STAT cascade|inhibition of JAK-STAT cascade|down regulation of JAK-STAT cascade|negative regulation of STAT protein nuclear translocation										GO:2000365			biological_process											owl:Class	
GO:0072483	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017035	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003126	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019282	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010000	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072626	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060356	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072607	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032751	biolink:NamedThing	positive regulation of interleukin-27 production	Any process that activates or increases the frequency, rate, or extent of interleukin-27 production.	got7fsn_ti	up regulation of interleukin-27 production|positive regulation of IL-27 production|activation of interleukin-27 production|upregulation of interleukin-27 production|up-regulation of interleukin-27 production|positive regulation of interleukin-27 anabolism|stimulation of interleukin-27 production|positive regulation of interleukin-27 biosynthetic process										GO:0045539			biological_process											owl:Class	
GO:0102008	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019192	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005904	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019067	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015639	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018440	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150160	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015598	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031195	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030434	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033155	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052261	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061019	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016073	biolink:NamedThing	snRNA metabolic process	The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.	got7fsn_ti	snRNA metabolism													biological_process											owl:Class	
GO:1902420	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001044	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017127	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030469	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052252	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905056	biolink:NamedThing	P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	A calcium-transporting P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration.	got7fsn_ti	Ca2+-pumping ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|plasma membrane Ca-ATPase involved in regulation of presynaptic cytosolic calcium ion concentration|ATP phosphohydrolase (Ca2+-transporting) involved in regulation of presynaptic cytosolic calcium ion concentration|Ca2+-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of presynaptic cytosolic calcium levels|calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium efflux ATPase involved in regulation of presynaptic cytosolic calcium ion concentration|Ca(2+)-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium ABC transporter involved in regulation of presynaptic cytosolic calcium ion concentration|calcium-translocating P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration						dos	2016-03-17T14:35:25Z						molecular_function											owl:Class	
GO:0035537	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097461	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008099	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048177	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032726	biolink:NamedThing	positive regulation of hepatocyte growth factor production	Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production.	got7fsn_ti	positive regulation of HGF production|stimulation of hepatocyte growth factor production|positive regulation of scatter factor production|up regulation of hepatocyte growth factor production|upregulation of hepatocyte growth factor production|up-regulation of hepatocyte growth factor production|activation of hepatocyte growth factor production|positive regulation of hepatocyte growth factor biosynthetic process										GO:0048177			biological_process											owl:Class	
GO:0008589	biolink:NamedThing	regulation of smoothened signaling pathway	Any process that modulates the frequency, rate or extent of smoothened signaling.	got7fsn_ti	regulation of hedgehog signaling pathway|regulation of smoothened by patched|regulation of smoothened signalling pathway|regulation of smoothened receptor activity by patched|regulation of hh signaling pathway|regulation of smoothened activity										GO:0007226|GO:0043109			biological_process											owl:Class	
GO:0075129	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072472	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004431	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016654	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034330	biolink:NamedThing	cell junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.	got7fsn_ti	cell junction biogenesis|cell junction assembly and maintenance|cell junction organisation													biological_process											owl:Class	
GO:0034500	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017037	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043284	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001948	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000598	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903362	biolink:NamedThing	regulation of cellular protein catabolic process	Any process that modulates the frequency, rate or extent of cellular protein catabolic process.	got7fsn_ti	regulation of cellular protein degradation|regulation of cellular protein breakdown|regulation of cyclin catabolic process|regulation of degradation of cyclin|regulation of cyclin catabolism|regulation of cellular protein catabolism|regulation of cyclin degradation|regulation of cyclin breakdown						kmv	2014-08-21T15:05:45Z			GO:2000598			biological_process											owl:Class	
GO:0009598	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032649	biolink:NamedThing	regulation of interferon-gamma production	Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.	got7fsn_ti	regulation of interferon-gamma secretion|regulation of interferon-gamma biosynthetic process|regulation of type II interferon production										GO:0045072|GO:1902713			biological_process											owl:Class	
GO:0044767	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006374	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071149	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051868	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0047076	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019642	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017047	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102353	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033742	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044745	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0089718	biolink:NamedThing	amino acid import across plasma membrane	The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-amino acid import|amino acid import into cell|amino acid transmembrane import|L-amino acid uptake						jl	2012-11-14T14:21:41Z			GO:0043092|GO:0044745|GO:1902837			biological_process											owl:Class	
GO:0071822	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033057	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043391	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006381	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000482	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001203	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001037	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048182	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015559	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016177	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030243	biolink:NamedThing	cellulose metabolic process	The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.	got7fsn_ti	cellulose metabolism										GO:0016177			biological_process											owl:Class	
GO:1902217	biolink:NamedThing	erythrocyte apoptotic process	Any apoptotic process in an erythrocyte.	got7fsn_ti	RBC apoptotic process|red blood cell apoptosis|erythrocyte apoptosis|red blood cell apoptotic process|RBC apoptosis						rl	2013-06-13T10:02:29Z						biological_process											owl:Class	
GO:0050327	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004003	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042787	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002535	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075717	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038051	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042230	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150120	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048605	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042877	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060181	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009795	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099133	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008178	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052527	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002928	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005671	biolink:NamedThing	obsolete Ada2/Gcn5/Ada3 transcription activator complex	OBSOLETE. A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.	got7fsn_ti	ATAC complex	https://github.com/geneontology/go-ontology/issues/21335			This term was obsoleted because it was incorrectly annotated. Consider ADA complex ; GO:0140671 or ATAC complex; GO:0140672.	GO:0140671|GO:0140672				True	GO:0002928			cellular_component											owl:Class	
GO:0005087	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042510	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030024	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902400	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006961	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045349	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006758	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042234	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016522	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032569	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030499	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150157	biolink:NamedThing	regulation of interleukin-34 production	Any process that modulates the frequency, rate or extent of interleukin-34 production.	got7fsn_ti	interleukin-34 biosynthetic process|regulation of interleukin-34 biosynthetic process						bc	2020-01-06T16:30:44Z			GO:0150160|GO:0150156			biological_process											owl:Class	
GO:0048421	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035031	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048423	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048553	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902881	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043742	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001035	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044449	biolink:NamedThing	obsolete contractile fiber part	OBSOLETE. Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.	got7fsn_ti	contractile fibre component|muscle fiber component|muscle fibre component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0043292				True				cellular_component											owl:Class	
GO:0000392	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042094	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046652	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005226	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008559	biolink:NamedThing	ABC-type xenobiotic transporter activity	Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).	got7fsn_ti	PDR protein|multidrug-resistance protein|multidrug resistance exporter|ATP-dependent xenobiotic transmembrane transporter activity|MDR protein|xenobiotic ABC transporter|ATPase-coupled xenobiotic transmembrane transporter activity|pleiotropic-drug-resistance protein|ATP phosphohydrolase (xenobiotic-exporting)|xenobiotic transmembrane transporting ATPase activity|P-glycoprotein										GO:0005226|GO:0008560	EC:7.6.2.2|MetaCyc:3.6.3.44-RXN		molecular_function											owl:Class	
GO:0003869	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044266	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018918	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051855	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052663	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004006	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003936	biolink:NamedThing	obsolete hydrogen-transporting two-sector ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out).	got7fsn_ti	hydrogen-transporting two-sector ATPase activity|proton-transporting two-sector ATPase activity				This term was made obsolete because it refers to a bifunctional gene product.	GO:0046933|GO:0046961				True	GO:0004006|GO:0008729			molecular_function											owl:Class	
GO:0019925	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042527	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034621	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902522	biolink:NamedThing	response to 4'-epidoxorubicin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.	got7fsn_ti	response to epirubicin				Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:44:31Z						biological_process											owl:Class	
GO:0032513	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001131	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045286	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001180	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060150	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099147	biolink:NamedThing	extrinsic component of postsynaptic density membrane	The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti							dos	2017-07-05T10:44:43Z						cellular_component											owl:Class	
GO:0072413	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0055027	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090099	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001133	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052280	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051768	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007045	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042225	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003753	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016538	biolink:NamedThing	cyclin-dependent protein serine/threonine kinase regulator activity	Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.	got7fsn_ti	G1/S-specific cyclin|cyclin-dependent protein kinase, intrinsic regulator activity|cyclin|G2/M-specific cyclin|cyclin-dependent protein kinase regulator activity										GO:0003752|GO:0003753|GO:0003751	Reactome:R-HSA-3215385|EC:2.7.1.-		molecular_function											owl:Class	
GO:0005860	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051534	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070885	biolink:NamedThing	negative regulation of calcineurin-NFAT signaling cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.	got7fsn_ti	down regulation of calcineurin-NFAT signaling cascade|inhibition of calcineurin-NFAT signaling cascade|inhibition of NFAT protein import into nucleus|negative regulation of calcineurin-NFAT signaling pathway|negative regulation of NFAT protein import into nucleus|downregulation of calcineurin-NFAT signaling cascade|negative regulation of calcineurin-NFAT signalling cascade|termination of calcineurin-NFAT signaling cascade|down-regulation of calcineurin-NFAT signaling cascade						mah	2009-08-26T03:29:33Z			GO:0051534			biological_process											owl:Class	
GO:0045379	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033279	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050443	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045368	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032736	biolink:NamedThing	positive regulation of interleukin-13 production	Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.	got7fsn_ti	upregulation of interleukin-13 production|positive regulation of interleukin-13 biosynthetic process|up-regulation of interleukin-13 production|positive regulation of interleukin-13 secretion|activation of interleukin-13 production|up regulation of interleukin-13 production|stimulation of interleukin-13 production|positive regulation of IL-13 production										GO:2000667|GO:0045368			biological_process											owl:Class	
GO:1990054	biolink:NamedThing	response to temozolomide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		pr	2013-02-22T10:09:44Z						biological_process											owl:Class	
GO:0016349	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008560	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018371	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071148	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019224	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008895	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043925	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015082	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018369	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903262	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004685	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004891	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051243	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903887	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045085	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032703	biolink:NamedThing	negative regulation of interleukin-2 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.	got7fsn_ti	down-regulation of interleukin-2 production|negative regulation of IL-2 production|inhibition of interleukin-2 production|down regulation of interleukin-2 production|negative regulation of interleukin-2 secretion|negative regulation of interleukin-2 biosynthetic process|downregulation of interleukin-2 production										GO:1900041|GO:0045085			biological_process											owl:Class	
GO:0050718	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043033	biolink:NamedThing	isoamylase complex	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages.	got7fsn_ti	debranching enzyme complex													cellular_component											owl:Class	
GO:2000663	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032714	biolink:NamedThing	negative regulation of interleukin-5 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.	got7fsn_ti	down regulation of interleukin-5 production|negative regulation of IL-5 production|downregulation of interleukin-5 production|inhibition of interleukin-5 production|negative regulation of interleukin-5 secretion|down-regulation of interleukin-5 production|negative regulation of interleukin-5 biosynthetic process										GO:2000663|GO:0045406			biological_process											owl:Class	
GO:1902739	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032647	biolink:NamedThing	regulation of interferon-alpha production	Any process that modulates the frequency, rate, or extent of interferon-alpha production.	got7fsn_ti	regulation of interferon-alpha secretion|regulation of interferon-alpha biosynthetic process										GO:0045354|GO:1902739			biological_process											owl:Class	
GO:0005403	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046801	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009096	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015542	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016168	biolink:NamedThing	chlorophyll binding	Binding to a chlorophyll; a compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.	got7fsn_ti														molecular_function											owl:Class	
GO:0000925	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902968	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019739	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007609	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009591	biolink:NamedThing	obsolete perception of mechanical stimulus	OBSOLETE. The series of events by which a mechanical stimulus is received by a cell and converted into a molecular signal.	got7fsn_ti	perception of mechanical stimulus				This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage.	GO:0050954				True	GO:0007609			biological_process											owl:Class	
GO:0052456	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000662	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032674	biolink:NamedThing	regulation of interleukin-5 production	Any process that modulates the frequency, rate, or extent of interleukin-5 production.	got7fsn_ti	regulation of interleukin-5 secretion|regulation of IL-5 production|regulation of interleukin-5 biosynthetic process										GO:0045405|GO:2000662			biological_process											owl:Class	
GO:0005312	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903363	biolink:NamedThing	negative regulation of cellular protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process.	got7fsn_ti	inhibition of cellular protein catabolic process|downregulation of cellular protein degradation|downregulation of cellular protein catabolism|down-regulation of cellular protein breakdown|negative regulation of cellular protein degradation|negative regulation of cellular protein breakdown|negative regulation of cyclin catabolism|down regulation of cellular protein catabolic process|inhibition of cellular protein degradation|down-regulation of cellular protein degradation|negative regulation of degradation of cyclin|negative regulation of cyclin degradation|negative regulation of cyclin catabolic process|inhibition of cellular protein catabolism|down-regulation of cellular protein catabolic process|down regulation of cellular protein degradation|down-regulation of cellular protein catabolism|downregulation of cellular protein catabolic process|downregulation of cellular protein breakdown|negative regulation of cyclin breakdown|inhibition of cellular protein breakdown|down regulation of cellular protein catabolism|negative regulation of cellular protein catabolism|down regulation of cellular protein breakdown						kmv	2014-08-21T15:05:53Z			GO:2000599			biological_process											owl:Class	
GO:0042485	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042482	biolink:NamedThing	positive regulation of odontogenesis	Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.	got7fsn_ti	positive regulation of tooth development|up regulation of odontogenesis|positive regulation of odontogenesis of calcareous or chitinous tooth|upregulation of odontogenesis|stimulation of odontogenesis|up-regulation of odontogenesis|activation of odontogenesis										GO:0042485			biological_process											owl:Class	
GO:0048120	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001180	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036079	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045538	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030179	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045404	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102437	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022844	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006938	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072661	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015396	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042108	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042229	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099182	biolink:NamedThing	presynaptic intermediate filament cytoskeleton	The intermediate filament cytoskeleton that is part of a presynapse.	got7fsn_ti							dos	2017-12-01T18:10:21Z						cellular_component											owl:Class	
GO:0075122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045153	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045076	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032663	biolink:NamedThing	regulation of interleukin-2 production	Any process that modulates the frequency, rate, or extent of interleukin-2 production.	got7fsn_ti	regulation of IL-2 production|regulation of interleukin-2 biosynthetic process|regulation of interleukin-2 secretion										GO:0045076|GO:1900040			biological_process											owl:Class	
GO:0047984	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034636	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902095	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017034	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903276	biolink:NamedThing	regulation of sodium ion export across plasma membrane	Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane.	got7fsn_ti	regulation of sodium export|regulation of sodium ion export|regulation of sodium ion export from cell						rl	2014-08-08T17:06:46Z			GO:1903273			biological_process											owl:Class	
GO:0042050	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051505	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007459	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001719	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032582	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001041	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030498	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009054	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045086	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019063	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042512	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072395	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044445	biolink:NamedThing	obsolete cytosolic part	OBSOLETE. Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components.	got7fsn_ti	cytosol component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005829				True				cellular_component											owl:Class	
GO:0019053	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015249	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097460	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016974	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032749	biolink:NamedThing	positive regulation of interleukin-25 production	Any process that activates or increases the frequency, rate, or extent of interleukin-25 production.	got7fsn_ti	upregulation of interleukin-25 production|stimulation of interleukin-25 production|up regulation of interleukin-25 production|activation of interleukin-25 production|positive regulation of interleukin-25 biosynthetic process|up-regulation of interleukin-25 production|positive regulation of interleukin-25 secretion|positive regulation of IL-25 production						bc	2019-12-09T16:51:44Z			GO:0045537|GO:0150150			biological_process											owl:Class	
GO:0046675	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042233	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090450	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071436	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006980	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990141	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002226	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045375	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001143	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902828	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052501	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007024	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009681	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048154	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043345	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042089	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045554	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015178	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016245	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090509	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098716	biolink:NamedThing	nickel cation import across plasma membrane	The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	nickel cation import into cell						tb	2012-11-16T16:12:53Z			GO:0090509			biological_process											owl:Class	
GO:0045449	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045256	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044116	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035412	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004759	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006358	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072424	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019641	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009680	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043339	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001622	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075716	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006445	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042112	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008602	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042526	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042531	biolink:NamedThing	positive regulation of tyrosine phosphorylation of STAT protein	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	got7fsn_ti	stimulation of tyrosine phosphorylation of Stat7 protein|up-regulation of tyrosine phosphorylation of Stat7 protein|upregulation of tyrosine phosphorylation of Stat1 protein|activation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat2 protein|upregulation of tyrosine phosphorylation of Stat2 protein|up-regulation of tyrosine phosphorylation of Stat3 protein|activation of tyrosine phosphorylation of Stat2 protein|up regulation of tyrosine phosphorylation of Stat6 protein|activation of tyrosine phosphorylation of Stat3 protein|stimulation of tyrosine phosphorylation of Stat5 protein|up regulation of tyrosine phosphorylation of Stat7 protein|up-regulation of tyrosine phosphorylation of Stat1 protein|up regulation of tyrosine phosphorylation of STAT protein|up regulation of tyrosine phosphorylation of Stat1 protein|activation of tyrosine phosphorylation of STAT protein|activation of tyrosine phosphorylation of Stat6 protein|stimulation of tyrosine phosphorylation of Stat6 protein|up-regulation of tyrosine phosphorylation of Stat4 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|up-regulation of tyrosine phosphorylation of STAT protein|activation of tyrosine phosphorylation of Stat7 protein|activation of tyrosine phosphorylation of Stat4 protein|upregulation of tyrosine phosphorylation of Stat5 protein|stimulation of tyrosine phosphorylation of Stat1 protein|stimulation of tyrosine phosphorylation of Stat2 protein|up-regulation of tyrosine phosphorylation of Stat6 protein|up regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat6 protein|up regulation of tyrosine phosphorylation of Stat4 protein|stimulation of tyrosine phosphorylation of Stat3 protein|upregulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat4 protein|upregulation of tyrosine phosphorylation of STAT protein|up-regulation of tyrosine phosphorylation of Stat2 protein|up regulation of tyrosine phosphorylation of Stat5 protein|activation of tyrosine phosphorylation of Stat5 protein|positive regulation of tyrosine phosphorylation of Stat1 protein|up regulation of tyrosine phosphorylation of Stat2 protein|upregulation of tyrosine phosphorylation of Stat7 protein|positive regulation of tyrosine phosphorylation of Stat7 protein|up-regulation of tyrosine phosphorylation of Stat5 protein|upregulation of tyrosine phosphorylation of Stat4 protein|stimulation of tyrosine phosphorylation of STAT protein|stimulation of tyrosine phosphorylation of Stat4 protein|upregulation of tyrosine phosphorylation of Stat6 protein										GO:0042517|GO:0042515|GO:0042529|GO:0042511|GO:0042520|GO:0042526|GO:0042523			biological_process											owl:Class	
GO:0089712	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006873	biolink:NamedThing	cellular ion homeostasis	Any process involved in the maintenance of an internal steady state of ions at the level of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0005390	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008900	biolink:NamedThing	P-type potassium:proton transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).	got7fsn_ti	H(+)/K(+)-ATPase activity|H(+)/K(+)-exchanging ATPase activity|(K+ + H+)-ATPase activity|H+/K+-exchanging ATPase activity|gastric H+/K+ ATPase|ATP phosphohydrolase (H+/K+-exchanging)|hydrogen:potassium-exchanging ATPase activity|H+/K+-ATPase activity|potassium:proton exchanging ATPase activity|gastric H(+)/K(+) ATPase activity|proton pump activity|H+-K+-ATPase activity|H,K-ATPase activity|hydrogen/potassium-exchanging ATPase activity|hydrogen:potassium exchanging ATPase activity	https://github.com/geneontology/go-ontology/issues/20821									GO:0005390	EC:7.2.2.19|Reactome:R-HSA-937311|RHEA:22044		molecular_function											owl:Class	
GO:0045354	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044236	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015088	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007461	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000999	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052044	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038042	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022816	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061748	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016439	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042515	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005485	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035086	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010163	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006811	biolink:NamedThing	ion transport	The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0072480	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048418	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097458	biolink:NamedThing	obsolete neuron part	OBSOLETE. Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.	got7fsn_ti						CL:0000540	pr	2012-12-19T16:53:50Z		True				cellular_component											owl:Class	
GO:2001202	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000941	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900920	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002036	biolink:NamedThing	regulation of L-glutamate import across plasma membrane	Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.	got7fsn_ti	regulation of L-glutamate uptake|regulation of L-glutamate transport|regulation of L-glutamate import						al	2012-06-13T07:34:08Z			GO:1900920			biological_process											owl:Class	
GO:0001043	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045788	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042831	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015455	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901368	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072026	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030480	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004647	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045081	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071850	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008577	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052251	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016927	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048121	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044757	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052853	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044433	biolink:NamedThing	obsolete cytoplasmic vesicle part	OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0031410				True				cellular_component											owl:Class	
GO:0075516	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005857	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090196	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072610	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048435	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051533	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903813	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010534	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0023015	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061488	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004975	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0106287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051910	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042028	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099159	biolink:NamedThing	regulation of modification of postsynaptic structure	Any process that modulates the frequency, rate or extent of modification of postsynaptic structure.	got7fsn_ti	regulation of postsynapse remodelling						dos	2017-08-25T15:47:55Z						biological_process											owl:Class	
GO:0048428	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001201	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071634	biolink:NamedThing	regulation of transforming growth factor beta production	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.	got7fsn_ti	regulation of transforming growth factor-beta production|regulation of TGFbeta production|regulation of TGF-B production|regulation of TGFB production|regulation of transforming growth factor-beta secretion|regulation of TGF-beta production						mah	2010-02-12T10:33:07Z			GO:2001201			biological_process											owl:Class	
GO:0032521	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052269	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007177	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072406	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006319	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044426	biolink:NamedThing	obsolete cell wall part	OBSOLETE. Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005618				True				cellular_component											owl:Class	
GO:0045452	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044369	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016302	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018346	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990541	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006843	biolink:NamedThing	mitochondrial citrate transmembrane transport	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix.	got7fsn_ti	mitochondrial citrate transport						vw	2014-11-19T11:08:45Z			GO:1990541			biological_process											owl:Class	
GO:0047523	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031188	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051806	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042348	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090233	biolink:NamedThing	negative regulation of spindle checkpoint	Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.	got7fsn_ti	spindle checkpoint silencing				Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).		tb	2010-01-20T10:29:43Z						biological_process											owl:Class	
GO:0071997	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015431	biolink:NamedThing	ABC-type glutathione S-conjugate transporter activity	Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out).	got7fsn_ti	conjugate transporter activity|ATP-dependent glutathione S-conjugate export pump|MRP1/GS-X pump|GS-X pump|ATPase-coupled glutathione S-conjugate transmembrane transporter activity|glutathione S-conjugate-exporting ATPase activity|glutathione S-conjugate-transporting ATPase activity						mah	2010-10-25T02:32:02Z			GO:0071997	RHEA:19121|EC:7.6.2.3		molecular_function											owl:Class	
GO:0031548	biolink:NamedThing	regulation of brain-derived neurotrophic factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.	got7fsn_ti	regulation of BDNF receptor signaling pathway|regulation of brain-derived neurotrophic factor receptor signalling pathway|regulation of BDNF receptor signalling pathway													biological_process											owl:Class	
GO:0043239	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033035	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099158	biolink:NamedThing	regulation of recycling endosome localization within postsynapse	Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse.	got7fsn_ti							dos	2017-08-25T15:37:50Z						biological_process											owl:Class	
GO:0042517	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052388	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038125	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031574	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098929	biolink:NamedThing	extrinsic component of spine apparatus membrane	The component of the spine apparatus membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0000420	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030349	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008223	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990240	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900040	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008699	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001136	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990289	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042384	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075146	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045361	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032692	biolink:NamedThing	negative regulation of interleukin-1 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production.	got7fsn_ti	negative regulation of interleukin-1 biosynthetic process|down regulation of interleukin-1 production|inhibition of interleukin-1 production|downregulation of interleukin-1 production|negative regulation of interleukin-1 secretion|negative regulation of IL-1 production|down-regulation of interleukin-1 production										GO:0045361|GO:0050711			biological_process											owl:Class	
GO:0071145	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098939	biolink:NamedThing	dendritic transport of mitochondrion	The directed movement of mitochondria along microtubules in nerve cell dendrites.	got7fsn_ti														biological_process											owl:Class	
GO:0090479	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031572	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061491	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098718	biolink:NamedThing	serine import across plasma membrane	The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	serine import into cell						dph	2012-12-06T14:55:29Z			GO:0061491			biological_process											owl:Class	
GO:0031675	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052518	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102567	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032313	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061461	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903719	biolink:NamedThing	regulation of I-kappaB phosphorylation	Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation.	got7fsn_ti	regulation of IKB phosphorylation|regulation of IkappaB phosphorylation|regulation of inhibitor of kappaB phosphorylation|regulation of inhibitor of NF-kappaB phosphorylation						lb	2014-12-08T15:45:07Z						biological_process											owl:Class	
GO:1902094	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901912	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098674	biolink:NamedThing	extrinsic component of neuronal dense core vesicle membrane	The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti							dos	2017-01-17T16:20:56Z						cellular_component											owl:Class	
GO:0004404	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044763	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030357	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070362	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019106	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016951	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099188	biolink:NamedThing	postsynaptic cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.	got7fsn_ti							dos	2017-12-20T15:06:57Z						biological_process											owl:Class	
GO:0000975	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043869	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006765	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015938	biolink:NamedThing	coenzyme A catabolic process	The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	got7fsn_ti	CoA catabolism|coenzyme A degradation|coenzyme A catabolism|coenzyme A breakdown										GO:0006765			biological_process											owl:Class	
GO:0034273	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042298	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043986	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017191	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016481	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006827	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098938	biolink:NamedThing	actin cytoskeleton of dendritic spine	The actin cytoskeleton that is part of a dendritic spine.	got7fsn_ti														cellular_component											owl:Class	
GO:0019201	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018093	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019613	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905055	biolink:NamedThing	calcium:cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.	got7fsn_ti	calcium ion antiporter activity involved in regulation of presynaptic cytosolic calcium levels						dos	2016-03-17T14:35:35Z						molecular_function											owl:Class	
GO:0072411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006138	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001102	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045791	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034262	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905078	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030360	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016489	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001179	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050725	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042522	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000499	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007467	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045384	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048119	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003981	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016789	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072471	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050475	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090525	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032661	biolink:NamedThing	regulation of interleukin-18 production	Any process that modulates the frequency, rate, or extent of interleukin-18 production.	got7fsn_ti	regulation of interleukin-18 biosynthetic process|regulation of IL-18 production|regulation of interleukin-18 secretion										GO:0150120|GO:0045381			biological_process											owl:Class	
GO:0071150	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070793	biolink:NamedThing	regulation of conidiophore development	Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.	got7fsn_ti							mah	2009-07-08T03:04:29Z						biological_process											owl:Class	
GO:0016510	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032731	biolink:NamedThing	positive regulation of interleukin-1 beta production	Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.	got7fsn_ti	upregulation of interleukin-1 beta production|activation of interleukin-1 beta production|up regulation of interleukin-1 beta production|positive regulation of IL-1 beta production|stimulation of interleukin-1 beta production|positive regulation of interleukin-1 beta biosynthetic process|positive regulation of interleukin-1 beta secretion|up-regulation of interleukin-1 beta production										GO:0050718|GO:0050725			biological_process											owl:Class	
GO:0042678	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030918	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009599	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006321	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903807	biolink:NamedThing	L-threonine import across plasma membrane	The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-threonine uptake|L-threonine import into cell|L-threonine import						bf	2012-05-11T10:46:21Z			GO:0036231			biological_process											owl:Class	
GO:0042503	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019421	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030407	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905076	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901134	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060257	biolink:NamedThing	negative regulation of flocculation	Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.	got7fsn_ti	negative regulation of coflocculation	https://github.com/geneontology/go-ontology/issues/20192|https://github.com/geneontology/go-ontology/issues/18785					al	2012-07-12T07:17:11Z			GO:1901134			biological_process											owl:Class	
GO:0052294	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019188	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035786	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902837	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048128	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050712	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990204	biolink:NamedThing	oxidoreductase complex	Any protein complex that possesses oxidoreductase activity.	got7fsn_ti	redox complex|oxidation-reduction complex						bhm	2013-10-07T08:24:47Z						cellular_component											owl:Class	
GO:0036232	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903808	biolink:NamedThing	L-tyrosine import across plasma membrane	The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-tyrosine import into cell|L-tyrosine uptake|L-tyrosine import						bf	2012-05-11T10:46:21Z			GO:0036232			biological_process											owl:Class	
GO:0008708	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072428	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017031	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052567	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030524	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044246	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003889	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044797	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902536	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075141	biolink:NamedThing	obsolete symbiont tolerance to host environment	OBSOLETE. Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against the components of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	maintenance of symbiont tolerance to host iron concentration|maintenance of symbiont tolerance to host pH environment|maintenance of symbiont tolerance to host oxygen tension environment|maintenance of symbiont tolerance to host environment|maintenance of symbiont tolerance to host osmotic environment|maintenance of symbiont tolerance to host redox environment	https://github.com/geneontology/go-ontology/issues/19099|https://github.com/geneontology/go-ontology/issues/18827			This term was obsoleted because it is redundant with other terms.	GO:0052200				True	GO:0075144|GO:0075238|GO:0075146|GO:0075143|GO:0075142			biological_process											owl:Class	
GO:0007544	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010173	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009364	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034048	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018476	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990126	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019587	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046397	biolink:NamedThing	galacturonate catabolic process	The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid.	got7fsn_ti	galacturonate breakdown|galacturonate catabolism|galacturonate degradation										GO:0019587			biological_process											owl:Class	
GO:0001593	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043689	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072458	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043092	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902658	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902657	biolink:NamedThing	protein localization to prospore membrane	A process in which a protein is transported to, or maintained in, a location within a prospore membrane.	got7fsn_ti	protein-prospore membrane targeting|establishment of protein localization to prospore membrane|protein localisation in prospore membrane|protein localisation to prospore membrane|protein targeting to prospore membrane|protein targeting to forespore membrane|protein targeting to FSM|establishment of protein localisation to prospore membrane|establishment of protein localization in prospore membrane|establishment of protein localisation in prospore membrane|protein targeting to ascospore-type prospore membrane|protein localization in prospore membrane						dph	2011-11-16T11:28:26Z			GO:1902658|GO:0072693			biological_process											owl:Class	
GO:0044086	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048234	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044370	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008749	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099522	biolink:NamedThing	cytosolic region	Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.	got7fsn_ti	region of cytosol													cellular_component											owl:Class	
GO:0003124	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038126	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051824	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045447	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902477	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018385	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001203	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004279	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004293	biolink:NamedThing	obsolete tissue kallikrein activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.	got7fsn_ti	salivary kallikrein|padutin|tissue kallikrein activity|kininogenin activity|glandular kallikrein activity|kallidinogenase|glumorin|submandibular kallikrein|padreatin|onokrein P|pancreatic kallikrein|urokallikrein|kidney kallikrein|depot-padutin|bradykininogenase|urinary kallikrein|callicrein|submaxillary kallikrein|kininogenase|dilminal D			GO:0004252	This term was made obsolete because it represents a gene product.					True	GO:0004279			molecular_function											owl:Class	
GO:0048426	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018348	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001103	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042833	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070754	biolink:NamedThing	regulation of interleukin-35 production	Any process that modulates the frequency, rate, or extent of interleukin-35 production.	got7fsn_ti	regulation of IL-35 production|regulation of interleukin-35 biosynthetic process						mah	2009-06-23T01:29:17Z			GO:0070750			biological_process											owl:Class	
GO:0042055	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001048	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901977	biolink:NamedThing	negative regulation of cell cycle checkpoint	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.	got7fsn_ti	downregulation of cell cycle checkpoint|negative regulation of G1/S transition checkpoint|down regulation of cell cycle checkpoint|down-regulation of cell cycle checkpoint|negative regulation of G1/S checkpoint|inhibition of cell cycle checkpoint				Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).		jl	2013-03-06T15:10:29Z			GO:2001048			biological_process											owl:Class	
GO:0150134	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032713	biolink:NamedThing	negative regulation of interleukin-4 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.	got7fsn_ti	down regulation of interleukin-4 production|negative regulation of interleukin-4 biosynthetic process|inhibition of interleukin-4 production|negative regulation of interleukin-4 secretion|down-regulation of interleukin-4 production|negative regulation of IL-4 production|downregulation of interleukin-4 production						bc				GO:0150134|GO:0045403			biological_process											owl:Class	
GO:0016283	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018468	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905950	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043081	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005529	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061165	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016280	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010576	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045380	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032740	biolink:NamedThing	positive regulation of interleukin-17 production	Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.	got7fsn_ti	activation of interleukin-17 production|upregulation of interleukin-17 production|stimulation of interleukin-17 production|positive regulation of interleukin-17 secretion|positive regulation of CTLA-8 production|positive regulation of interleukin-17 biosynthetic process|positive regulation of Cytotoxic T-lymphocyte-associated antigen 8 production|up regulation of interleukin-17 production|up-regulation of interleukin-17 production|positive regulation of IL-17 production										GO:0045380|GO:1905078			biological_process											owl:Class	
GO:0019077	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001031	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071158	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042172	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007587	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016983	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018842	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099190	biolink:NamedThing	postsynaptic spectrin-associated cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse.	got7fsn_ti							dos	2017-12-20T15:34:26Z						biological_process											owl:Class	
GO:0005116	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009387	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090478	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045407	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902506	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008599	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043787	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004752	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044531	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007373	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032134	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008952	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001138	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903308	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097286	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072323	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008433	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0080138	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045405	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033317	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042591	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044749	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004718	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046698	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904497	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004646	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990939	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019052	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045423	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032645	biolink:NamedThing	regulation of granulocyte macrophage colony-stimulating factor production	Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.	got7fsn_ti	regulation of GM-CSF production|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|regulation of granulocyte macrophage colony stimulating factor production										GO:0045423			biological_process											owl:Class	
GO:0044123	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030542	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903128	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007233	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016940	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045154	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0062178	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140252	biolink:NamedThing	regulation protein catabolic process at postsynapse	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/204			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:35:56Z						biological_process											owl:Class	
GO:0052509	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007330	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009370	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033724	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009281	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048432	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007151	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003895	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032750	biolink:NamedThing	positive regulation of interleukin-26 production	Any process that activates or increases the frequency, rate, or extent of interleukin-26 production.	got7fsn_ti	upregulation of interleukin-26 production|positive regulation of IL-26 production|activation of interleukin-26 production|up-regulation of interleukin-26 production|up regulation of interleukin-26 production|positive regulation of interleukin-26 biosynthetic process|stimulation of interleukin-26 production										GO:0045538			biological_process											owl:Class	
GO:0015683	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016478	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043089	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036439	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048558	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052329	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048220	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043351	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990373	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140564	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051833	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032514	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052069	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090631	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097481	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001024	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048412	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099181	biolink:NamedThing	structural constituent of presynapse	The action of a molecule that contributes to the structural integrity of a presynapse.	got7fsn_ti							dos	2017-12-20T13:42:46Z						molecular_function											owl:Class	
GO:0035856	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048178	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009391	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030387	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052385	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004695	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042295	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000351	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005103	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0103053	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060871	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009572	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044039	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019425	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006752	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006732	biolink:NamedThing	obsolete coenzyme metabolic process	OBSOLETE. The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	got7fsn_ti	coenzyme metabolism|group transfer coenzyme metabolism|group transfer coenzyme metabolic process|coenzyme and prosthetic group metabolic process|coenzyme and prosthetic group metabolism				1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True	GO:0006752			biological_process											owl:Class	
GO:0003708	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000021	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052311	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000823	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046756	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031794	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032859	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006764	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015937	biolink:NamedThing	coenzyme A biosynthetic process	The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	got7fsn_ti	coenzyme A anabolism|coenzyme A biosynthesis|CoA biosynthesis|coenzyme A formation|coenzyme A synthesis										GO:0006764	MetaCyc:PANTOSYN-PWY|MetaCyc:COA-PWY|MetaCyc:PWY-4221		biological_process											owl:Class	
GO:0046735	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070805	biolink:NamedThing	regulation of phialide development	Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.	got7fsn_ti							mah	2009-07-08T04:45:03Z						biological_process											owl:Class	
GO:0090622	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016001	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001205	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046764	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009797	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001220	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006985	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033710	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072434	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052551	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008095	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902705	biolink:NamedThing	hexose catabolic process to butyrate	The chemical reactions and pathways resulting in the breakdown of hexose to butyrate.	got7fsn_ti	acidogenesis|hexose catabolism to butyrate|hexose degradation to butyrate|hexose breakdown to butyrate						tb	2014-02-19T18:43:32Z			GO:1990287			biological_process											owl:Class	
GO:0045360	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032652	biolink:NamedThing	regulation of interleukin-1 production	Any process that modulates the frequency, rate, or extent of interleukin-1 production.	got7fsn_ti	regulation of interleukin-1 biosynthetic process|regulation of interleukin-1 secretion|regulation of IL-1 production										GO:0050704|GO:0045360			biological_process											owl:Class	
GO:0030928	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002217	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071435	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045235	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140236	biolink:NamedThing	translation at presynapse	Translation that occurs at the presynapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/216			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-13T13:00:33Z						biological_process											owl:Class	
GO:0019754	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051577	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150135	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032753	biolink:NamedThing	positive regulation of interleukin-4 production	Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.	got7fsn_ti	positive regulation of IL-4 production|upregulation of interleukin-4 production|positive regulation of interleukin-4 secretion|positive regulation of interleukin-4 biosynthetic process|up regulation of interleukin-4 production|stimulation of interleukin-4 production|activation of interleukin-4 production|up-regulation of interleukin-4 production										GO:0150135|GO:0045404			biological_process											owl:Class	
GO:0052284	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048267	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006453	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070128	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033681	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052345	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990283	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042916	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072474	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002739	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002718	biolink:NamedThing	regulation of cytokine production involved in immune response	Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.	got7fsn_ti	regulation of cytokine production during immune response|regulation of cytokine biosynthetic process involved in immune response|regulation of cytokine secretion involved in immune response										GO:0002739|GO:0002742			biological_process											owl:Class	
GO:0090544	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030454	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042223	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046953	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000506	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019378	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042553	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042674	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045398	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032747	biolink:NamedThing	positive regulation of interleukin-23 production	Any process that activates or increases the frequency, rate, or extent of interleukin-23 production.	got7fsn_ti	activation of interleukin-23 production|up regulation of interleukin-23 production|positive regulation of IL-23 production|stimulation of interleukin-23 production|upregulation of interleukin-23 production|up-regulation of interleukin-23 production|positive regulation of interleukin-23 biosynthetic process										GO:0045398			biological_process											owl:Class	
GO:1990944	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048607	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000505	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001047	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901976	biolink:NamedThing	regulation of cell cycle checkpoint	Any process that modulates the frequency, rate or extent of cell cycle checkpoint.	got7fsn_ti	regulation of G1/S checkpoint|regulation of G1/S transition checkpoint				Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).		jl	2013-03-06T15:10:20Z			GO:2001047			biological_process											owl:Class	
GO:0000397	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901546	biolink:NamedThing	regulation of synaptic vesicle lumen acidification	Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification.	got7fsn_ti	regulation of synaptic vesicle lumen proton loading|regulation of synaptic vesicle lumen pH reduction						dsf	2012-10-26T16:09:24Z						biological_process											owl:Class	
GO:0008308	biolink:NamedThing	voltage-gated anion channel activity	Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-dependent ion-selective channel activity|voltage-gated ion-selective channel activity										GO:0022844	Reactome:R-HSA-9012374		molecular_function											owl:Class	
GO:0030608	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075058	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018931	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016315	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008557	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090468	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090607	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018691	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902702	biolink:NamedThing	hexose catabolic process to propan-2-ol	The chemical reactions and pathways resulting in the breakdown of hexose to propan-2-ol.	got7fsn_ti	hexose catabolic process to isopropyl alcohol|hexose degradation to propan-2-ol|solventogenesis|hexose breakdown to propan-2-ol|hexose catabolism to propan-2-ol|hexose catabolic process to isopropanol						tb	2014-02-19T18:42:54Z			GO:1990283			biological_process											owl:Class	
GO:1990681	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009775	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036064	biolink:NamedThing	ciliary basal body	A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.	got7fsn_ti	kinetosome|cilium basal body|basal body|microtubule basal body|cilial basal body				In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.		bf	2011-12-15T10:40:20Z			GO:0005932	NIF_Subcellular:sao11978067		cellular_component											owl:Class	
GO:0009121	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007514	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046795	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905060	biolink:NamedThing	calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	got7fsn_ti	calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion levels						dos	2016-03-18T12:32:17Z						molecular_function											owl:Class	
GO:0045365	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003280	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031183	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048221	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904168	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097405	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098714	biolink:NamedThing	malate import across plasma membrane	The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	malate import into cell						pr	2012-10-29T11:18:48Z			GO:0097405			biological_process											owl:Class	
GO:1901603	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052153	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070970	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900921	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045909	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001645	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072693	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006994	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050702	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016066	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075057	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045419	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032758	biolink:NamedThing	positive regulation of interleukin-9 production	Any process that activates or increases the frequency, rate, or extent of interleukin-9 production.	got7fsn_ti	up-regulation of interleukin-9 production|upregulation of interleukin-9 production|up regulation of interleukin-9 production|positive regulation of interleukin-9 biosynthetic process|positive regulation of IL-9 production|activation of interleukin-9 production|stimulation of interleukin-9 production										GO:0045419			biological_process											owl:Class	
GO:0016448	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903956	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008400	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098611	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000998	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052298	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046613	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072605	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005661	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003892	biolink:NamedThing	obsolete proliferating cell nuclear antigen	OBSOLETE. A nuclear protein that associates as a trimer and then interacts with delta DNA polymerase and epsilon DNA polymerase, acting as an auxiliary factor for DNA replication and DNA repair.	got7fsn_ti	proliferating cell nuclear antigen|PCNA				This term was made obsolete because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True	GO:0005661			molecular_function											owl:Class	
GO:0032709	biolink:NamedThing	negative regulation of interleukin-25 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production.	got7fsn_ti	down-regulation of interleukin-25 production|downregulation of interleukin-25 production|inhibition of interleukin-25 production|negative regulation of interleukin-25 secretion|negative regulation of IL-25 production|down regulation of interleukin-25 production|negative regulation of interleukin-25 biosynthetic process										GO:0150149|GO:0045533			biological_process											owl:Class	
GO:0089711	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045385	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032702	biolink:NamedThing	negative regulation of interleukin-19 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production.	got7fsn_ti	down regulation of interleukin-19 production|negative regulation of IL-19 production|negative regulation of interleukin-19 biosynthetic process|inhibition of interleukin-19 production|down-regulation of interleukin-19 production|downregulation of interleukin-19 production										GO:0045385			biological_process											owl:Class	
GO:0019175	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052469	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033817	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0047318	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075008	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904360	biolink:NamedThing	negative regulation of spore germination	Any process that stops, prevents or reduces the frequency, rate or extent of spore germination.	got7fsn_ti	negative regulation of spore germination on or near host|downregulation of spore germination|down regulation of spore germination|down-regulation of spore germination|inhibition of spore germination						pf	2015-06-12T19:46:12Z			GO:0075008			biological_process											owl:Class	
GO:0045400	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006993	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035105	biolink:NamedThing	obsolete sterol regulatory element binding protein import into nucleus	OBSOLETE. The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.	got7fsn_ti	SREBP import into nucleus involved in sterol depletion response|sterol depletion response, sterol regulatory element binding protein import into nucleus|sterol regulatory element binding protein import into nucleus involved in sterol depletion response|sterol depletion response, SREBP import into nucleus|SREBP import into nucleus|SREBP nuclear translocation|sterol depletion response, SREBP nuclear translocation|sterol regulatory element binding protein nuclear translocation|sterol depletion response, sterol regulatory element binding protein nuclear translocation|sterol regulatory element binding protein nuclear translocation involved in sterol depletion response				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0042306|GO:0006606				True	GO:0006993			biological_process											owl:Class	
GO:0007328	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003890	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005339	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015008	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005699	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016425	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019127	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002163	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005069	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032842	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052271	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098675	biolink:NamedThing	intrinsic component of neuronal dense core vesicle membrane	The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to neuronal dense core granule membrane						dos	2017-01-17T16:22:44Z						cellular_component											owl:Class	
GO:0015815	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045374	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000066	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990575	biolink:NamedThing	mitochondrial L-ornithine transmembrane transport	The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti	mitochondrial ornithine transport|mitochondrial ornithine transmembrane transport						mah	2014-12-05T11:29:49Z			GO:0000066			biological_process											owl:Class	
GO:0002740	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022833	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000443	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007333	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140079	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016949	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001157	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015785	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015584	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042782	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060553	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052077	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000364	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030871	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051207	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902251	biolink:NamedThing	negative regulation of erythrocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process.	got7fsn_ti	downregulation of RBC apoptotic process|down-regulation of RBC apoptosis|down regulation of RBC apoptotic process|down regulation of RBC apoptosis|inhibition of erythrocyte apoptotic process|down-regulation of erythrocyte apoptotic process|down regulation of red blood cell apoptotic process|down-regulation of erythrocyte apoptosis|inhibition of erythrocyte apoptosis|downregulation of RBC apoptosis|negative regulation of erythrocyte apoptosis|down regulation of erythrocyte apoptosis|down regulation of erythrocyte apoptotic process|inhibition of red blood cell apoptotic process|down-regulation of red blood cell apoptosis|downregulation of red blood cell apoptotic process|inhibition of RBC apoptosis|downregulation of red blood cell apoptosis|negative regulation of RBC apoptotic process|negative regulation of red blood cell apoptosis|inhibition of RBC apoptotic process|down-regulation of red blood cell apoptotic process|negative regulation of RBC apoptosis|down-regulation of RBC apoptotic process|downregulation of erythrocyte apoptotic process|downregulation of erythrocyte apoptosis|down regulation of red blood cell apoptosis|inhibition of red blood cell apoptosis|negative regulation of red blood cell apoptotic process						rl	2013-06-20T19:30:59Z						biological_process											owl:Class	
GO:0015819	biolink:NamedThing	lysine transport	The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	lysine uptake|L-lysine transport|lysine import|L-lysine import						dph	2012-10-05T10:22:26Z			GO:0034226|GO:0061461			biological_process											owl:Class	
GO:0005325	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004926	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018368	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018086	biolink:NamedThing	obsolete alanine racemization	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	alanine racemization				This term was made obsolete because it was replaced with more appropriate terms.	GO:0019122				True	GO:0018368			biological_process											owl:Class	
GO:0015618	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005471	biolink:NamedThing	ATP:ADP antiporter activity	Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out).	got7fsn_ti	ATP/ADP exchanger|ADP/ATP translocase|adenine nucleotide translocase|ADP/ATP carrier protein|ATP/ADP exchange										GO:0005349			molecular_function											owl:Class	
GO:0005286	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071156	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008054	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052441	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072516	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015027	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005478	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990598	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038049	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001183	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051812	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904190	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006819	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075128	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044798	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015672	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033205	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019663	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045733	biolink:NamedThing	acetate catabolic process	The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.	got7fsn_ti	homoacetate catabolic process|acetate breakdown|acetate catabolism|acetate degradation										GO:0019663			biological_process											owl:Class	
GO:0045406	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031182	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052304	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052382	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036277	biolink:NamedThing	response to anticonvulsant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T02:40:12Z						biological_process											owl:Class	
GO:0010531	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003749	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090569	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048470	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061164	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006773	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008614	biolink:NamedThing	pyridoxine metabolic process	The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti	pyridoxine metabolism										GO:0006773			biological_process											owl:Class	
GO:0047607	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000355	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042514	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002641	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004863	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008426	biolink:NamedThing	protein kinase C inhibitor activity	Binds to and stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein.	got7fsn_ti	PKC inhibitor activity|diacylglycerol-activated phospholipid-dependent protein kinase C inhibitor activity|diacylglycerol-activated phospholipid-dependent PKC inhibitor activity										GO:0004863			molecular_function											owl:Class	
GO:1902582	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015681	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006309	biolink:NamedThing	apoptotic DNA fragmentation	The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.	got7fsn_ti	DNA catabolism during apoptosis|chromatinolysis|DNA fragmentation|endonucleolytic DNA catabolic process involved in apoptosis|DNA fragmentation involved in apoptotic nuclear change|DNA catabolic process during apoptosis				DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).						GO:0008178			biological_process											owl:Class	
GO:0016982	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044117	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006087	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042502	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032845	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033318	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015991	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099102	biolink:NamedThing	G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential	Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential.	got7fsn_ti														molecular_function											owl:Class	
GO:0048112	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045817	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008520	biolink:NamedThing	L-ascorbate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in).	got7fsn_ti	sodium-dependent L-ascorbic acid transporter|sodium-dependent L-ascorbate transmembrane transporter activity						mah	2009-09-01T02:25:22Z			GO:0070890	TC:2.A.40.6.1		molecular_function											owl:Class	
GO:1990286	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003748	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000383	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098945	biolink:NamedThing	intrinsic component of presynaptic active zone membrane	The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to presynaptic acive zone membrane													cellular_component											owl:Class	
GO:0001140	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048113	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0020021	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016685	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044422	biolink:NamedThing	obsolete organelle part	OBSOLETE. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0043226				True				cellular_component											owl:Class	
GO:0140160	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033733	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000484	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032757	biolink:NamedThing	positive regulation of interleukin-8 production	Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.	got7fsn_ti	positive regulation of interleukin-8 secretion|up regulation of interleukin-8 production|activation of interleukin-8 production|positive regulation of interleukin-8 biosynthetic process|up-regulation of interleukin-8 production|upregulation of interleukin-8 production|stimulation of interleukin-8 production|positive regulation of IL-8 production										GO:2000484|GO:0045416			biological_process											owl:Class	
GO:0009774	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015197	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072620	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046733	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902368	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018735	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902302	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903764	biolink:NamedThing	regulation of potassium ion export across plasma membrane	Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane.	got7fsn_ti	regulation of potassium ion export|regulation of potassium export|regulation of potassium export across plasma membrane						rl	2013-07-17T16:39:53Z			GO:1902302			biological_process											owl:Class	
GO:0008264	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043071	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008059	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016238	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018375	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902264	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015320	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015317	biolink:NamedThing	phosphate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in).	got7fsn_ti	phosphate:hydrogen symporter activity|phosphate ion carrier activity	https://github.com/geneontology/go-ontology/issues/14221									GO:0015320			molecular_function											owl:Class	
GO:0052248	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044253	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045073	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001030	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102023	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046472	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097617	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004405	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072422	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007408	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990285	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035546	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003768	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048425	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015893	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004804	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006632	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099164	biolink:NamedThing	postsynaptic specialization membrane of symmetric synapse	The membrane component of the postsynaptic specialization of a symmetic synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.	got7fsn_ti							dos	2017-09-10T11:50:44Z						cellular_component											owl:Class	
GO:0001187	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052852	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052378	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016142	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016139	biolink:NamedThing	glycoside catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.	got7fsn_ti	O-glycoside catabolism|glycoside catabolism|glycoside degradation|glycoside breakdown|O-glycoside catabolic process|O-glycoside degradation|O-glycoside breakdown										GO:0016142			biological_process											owl:Class	
GO:0045556	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061460	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903810	biolink:NamedThing	L-histidine import across plasma membrane	The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	histidine import|L-histidine import|L-histidine import into cell						dph	2012-10-05T10:20:50Z			GO:0061460|GO:0090466			biological_process											owl:Class	
GO:0002716	biolink:NamedThing	negative regulation of natural killer cell mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity.	got7fsn_ti	negative regulation of natural killer cell activity|negative regulation of NK cell mediated immunity|downregulation of natural killer cell mediated immunity|inhibition of natural killer cell mediated immunity|down regulation of natural killer cell mediated immunity|down-regulation of natural killer cell mediated immunity|negative regulation of NK cell activity										GO:0030102			biological_process											owl:Class	
GO:0018696	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045090	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033613	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007222	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000508	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048590	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042115	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052186	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052380	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099090	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043141	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019004	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009618	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015684	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015509	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004871	biolink:NamedThing	obsolete signal transducer activity	OBSOLETE. Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.	got7fsn_ti	quorum sensing signal generator activity|hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity|quorum sensing response regulator activity	https://github.com/geneontology/go-ontology/issues/14232			This term was obsoleted because it was not clearly defined and is not a useful grouping term.					True	GO:0009370|GO:0009369|GO:0005062			molecular_function											owl:Class	
GO:0016961	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031888	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099531	biolink:NamedThing	presynaptic process involved in chemical synaptic transmission	The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission.	got7fsn_ti														biological_process											owl:Class	
GO:1902699	biolink:NamedThing	pentose catabolic process to acetate	The chemical reactions and pathways resulting in the breakdown of pentose to acetate.	got7fsn_ti	pentose breakdown to acetate|acidogenesis|pentose degradation to acetate|pentose catabolism to acetate						tb	2014-02-19T18:28:38Z			GO:1990289			biological_process											owl:Class	
GO:0052082	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000068	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150121	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032701	biolink:NamedThing	negative regulation of interleukin-18 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.	got7fsn_ti	negative regulation of interleukin-18 secretion|inhibition of interleukin-18 production|downregulation of interleukin-18 production|down-regulation of interleukin-18 production|negative regulation of interleukin-18 biosynthetic process|down regulation of interleukin-18 production|negative regulation of IL-18 production										GO:0045382|GO:0150121			biological_process											owl:Class	
GO:0015397	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046788	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060626	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060625	biolink:NamedThing	regulation of protein deneddylation	Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.	got7fsn_ti	regulation of cullin deneddylation						dph	2009-05-18T02:22:07Z			GO:0060626			biological_process											owl:Class	
GO:0003752	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015077	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008040	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052259	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052310	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030390	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098955	biolink:NamedThing	intrinsic component of presynaptic endosome membrane	The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to presynaptic endosome membrane													cellular_component											owl:Class	
GO:0005299	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045357	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004429	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015637	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090004	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004012	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:9606	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099603	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019006	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003703	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048063	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007331	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019275	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036274	biolink:NamedThing	response to lapatinib	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T02:02:26Z						biological_process											owl:Class	
GO:0015456	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015022	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048157	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045389	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000317	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051025	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000119	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019723	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032861	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008402	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022838	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045207	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005620	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006262	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008604	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032729	biolink:NamedThing	positive regulation of interferon-gamma production	Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.	got7fsn_ti	upregulation of interferon-gamma production|up regulation of interferon-gamma production|positive regulation of type II interferon production|positive regulation of interferon-gamma secretion|up-regulation of interferon-gamma production|positive regulation of interferon-gamma biosynthetic process|activation of interferon-gamma production|stimulation of interferon-gamma production										GO:0045078|GO:1902715			biological_process											owl:Class	
GO:0072511	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015660	biolink:NamedThing	formate efflux transmembrane transporter activity	Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	formate efflux permease activity										GO:0015509			molecular_function											owl:Class	
GO:0001012	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901238	biolink:NamedThing	ABC-type tungstate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out).	got7fsn_ti	tungstate transmembrane transporter activity|ATPase-coupled tungstate transmembrane transporter activity|tungstate transmembrane-transporting ATPase activity						jl	2012-08-07T14:47:36Z			GO:1901237	EC:7.3.2.6|RHEA:35027		molecular_function											owl:Class	
GO:0004701	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000600	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099025	biolink:NamedThing	anchored component of postsynaptic membrane	The component of the postsynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0003894	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003738	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043341	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070886	biolink:NamedThing	positive regulation of calcineurin-NFAT signaling cascade	Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.	got7fsn_ti	up-regulation of calcineurin-NFAT signaling cascade|positive regulation of NFAT protein import into nucleus|stimulation of calcineurin-NFAT signaling cascade|activation of calcineurin-NFAT signaling cascade|up regulation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signalling cascade|upregulation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signaling pathway						mah	2009-08-26T03:37:10Z			GO:0051533			biological_process											owl:Class	
GO:0036275	biolink:NamedThing	response to 5-fluorouracil	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.	got7fsn_ti	response to fluorouracil|response to 5-fluoropyrimidine-2,4(1H,3H)-dione				Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T02:08:23Z						biological_process											owl:Class	
GO:0032698	biolink:NamedThing	negative regulation of interleukin-15 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production.	got7fsn_ti	down regulation of interleukin-15 production|down-regulation of interleukin-15 production|downregulation of interleukin-15 production|negative regulation of IL-15 production|inhibition of interleukin-15 production|negative regulation of interleukin-15 biosynthetic process										GO:0045373			biological_process											owl:Class	
GO:0018089	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018514	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009564	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010802	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001045	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097312	biolink:NamedThing	obsolete bacterial biofilm matrix component	OBSOLETE. Any constituent part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.	got7fsn_ti	biofilm matrix part				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0097311	pr	2012-05-24T11:22:56Z		True				cellular_component											owl:Class	
GO:0019753	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031238	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900755	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005717	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052270	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044709	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001182	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004469	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032192	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045386	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043026	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072419	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071974	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:syngo_official_label	biolink:NamedThing	label approved by the SynGO project		got7fsn_ti																									owl:AnnotationProperty	
GO:0140235	biolink:NamedThing	RNA polyadenylation at postsynapse	A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-13T12:03:28Z						biological_process											owl:Class	
GO:0018999	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000824	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0047314	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052371	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007092	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015273	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032319	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0103019	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015239	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990292	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902697	biolink:NamedThing	valine catabolic process to isobutanol	The chemical reactions and pathways resulting in the breakdown of valine to isobutanol.	got7fsn_ti	valine breakdown to isobutanol|valine degradation to isobutanol|valine catabolism to isobutanol						tb	2014-02-19T18:28:19Z			GO:1990292			biological_process											owl:Class	
GO:0055099	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006317	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098999	biolink:NamedThing	extrinsic component of postsynaptic endosome membrane	The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0075326	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903822	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005086	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001789	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007022	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099578	biolink:NamedThing	regulation of translation at postsynapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0098701	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017097	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090003	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072604	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005224	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045044	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015300	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016930	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048547	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001150	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034961	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010003	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010535	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008971	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008497	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042228	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001189	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001513	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061600	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016535	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045502	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071842	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004008	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016022	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007466	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001625	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001017	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090097	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045432	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0023046	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099577	biolink:NamedThing	regulation of translation at presynapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating translation occurring at the presynapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0017144	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072646	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052443	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050222	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031186	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031171	biolink:NamedThing	ferricrocin biosynthetic process	The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.	got7fsn_ti	ferricrocin formation|ferricrocin synthesis|ferricrocin anabolism|ferricrocin biosynthetic process, peptide modification|ferricrocin biosynthetic process, peptide formation|ferricrocin biosynthesis										GO:0031185|GO:0031186			biological_process											owl:Class	
GO:0072603	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015511	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070869	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035084	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045673	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019291	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004434	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018056	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044457	biolink:NamedThing	obsolete cell septum part	OBSOLETE. Any constituent part of a cell septum, a structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0030428				True				cellular_component											owl:Class	
GO:0003765	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032725	biolink:NamedThing	positive regulation of granulocyte macrophage colony-stimulating factor production	Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.	got7fsn_ti	positive regulation of GM-CSF production|activation of granulocyte macrophage colony-stimulating factor production|upregulation of granulocyte macrophage colony-stimulating factor production|stimulation of granulocyte macrophage colony-stimulating factor production|positive regulation of granulocyte macrophage colony stimulating factor production|up regulation of granulocyte macrophage colony-stimulating factor production|up-regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process										GO:0045425			biological_process											owl:Class	
GO:0042095	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052263	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019225	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030347	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033109	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032318	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051546	biolink:NamedThing	keratinocyte migration	The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.	got7fsn_ti														biological_process											owl:Class	
GO:0015788	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001032	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900136	biolink:NamedThing	regulation of chemokine activity	Any process that modulates the frequency, rate or extent of chemokine activity.	got7fsn_ti							bf	2012-02-28T01:36:29Z						biological_process											owl:Class	
GO:1903717	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004280	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052000	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030396	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072622	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150133	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008522	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045426	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032746	biolink:NamedThing	positive regulation of interleukin-22 production	Any process that activates or increases the frequency, rate, or extent of interleukin-22 production.	got7fsn_ti	upregulation of interleukin-22 production|up regulation of interleukin-22 production|up-regulation of interleukin-22 production|activation of interleukin-22 production|stimulation of interleukin-22 production|positive regulation of IL-22 production|positive regulation of interleukin-22 biosynthetic process										GO:0045395			biological_process											owl:Class	
GO:0060359	biolink:NamedThing	response to ammonium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.	got7fsn_ti	response to ammonia										GO:1903717			biological_process											owl:Class	
GO:0018380	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902453	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052936	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060403	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031192	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:27896	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008329	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008323	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102315	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045245	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015402	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902479	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008524	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061513	biolink:NamedThing	glucose 6-phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).	got7fsn_ti	glucose 6-phosphate:phosphate antiporter activity						dph	2013-04-17T08:47:40Z			GO:0008524	Reactome:R-HSA-198513|Reactome:R-HSA-3229118|Reactome:R-HSA-3257122		molecular_function											owl:Class	
GO:1903129	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0022415	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032568	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005023	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097366	biolink:NamedThing	response to bronchodilator	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.	got7fsn_ti	response to broncholytic agent|response to bronchodilator agent				Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		pr	2012-08-01T16:13:31Z						biological_process											owl:Class	
GO:0001004	biolink:NamedThing	obsolete RNA polymerase III transcription regulator recruiting activity	OBSOLETE. Initiating the assembly of the RNA polymerase III pre-initiation complex by binding to a control sequence in the intragenic region. This allows to recruit TFIIIB to the DNA at a site centered approximately 26 base pairs upstream of the start site of transcription. For tRNA genes, TFIIIC first associates with DNA, and then recruits TFIIIB. For 5S rRNA genes, TFIIIA binds to DNA first, followed by TFIIIC, which then recruits TFIIIB.	got7fsn_ti	RNA polymerase III transcription factor recruiting activity|SNAPc-type activity|type 2 RNA polymerase III promoter recognition|transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting|type 3 RNA polymerase III promoter recognition|RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|RNA polymerase III type 3 promoter TFIIIB recruiting transcription factor activity|transcription factor activity, RNA polymerase III type 1 promoter TFIIIB|RNA polymerase III type 2 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|RNA polymerase III assembly factor activity|RNA polymerase III hybrid type promoter TFIIIB recruiting transcription factor activity|transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting|RNA polymerase III assembly factor activity, TFIIIB recruiting|TFIIIC-type activity|transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting|TFIIIA activity|RNA polymerase III promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|transcription factor activity, RNA polymerase III type 3 promoter TFIIIB recruiting	https://github.com/geneontology/go-ontology/issues/18561|https://github.com/geneontology/go-ontology/issues/14852			The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'.		krc	2010-08-18T05:53:32Z		True	GO:0001038|GO:0001008|GO:0001033|GO:0001157|GO:0001005			molecular_function											owl:Class	
GO:0071775	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000283	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032659	biolink:NamedThing	regulation of interleukin-16 production	Any process that modulates the frequency, rate, or extent of interleukin-16 production.	got7fsn_ti	regulation of IL-16 production|regulation of interleukin-16 biosynthetic process										GO:0045375			biological_process											owl:Class	
GO:0016792	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005659	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032695	biolink:NamedThing	negative regulation of interleukin-12 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.	got7fsn_ti	downregulation of interleukin-12 production|negative regulation of interleukin-12 secretion|negative regulation of CLMF production|down-regulation of interleukin-12 production|negative regulation of NKSF production|down regulation of interleukin-12 production|negative regulation of IL-12 production|negative regulation of interleukin-12 biosynthetic process|inhibition of interleukin-12 production										GO:0045083|GO:2001183			biological_process											owl:Class	
GO:0007332	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000753	biolink:NamedThing	cell morphogenesis involved in conjugation with cellular fusion	The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion.	got7fsn_ti	shmoo orientation|shmooing										GO:0007332			biological_process											owl:Class	
GO:0032738	biolink:NamedThing	positive regulation of interleukin-15 production	Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.	got7fsn_ti	activation of interleukin-15 production|stimulation of interleukin-15 production|upregulation of interleukin-15 production|up-regulation of interleukin-15 production|positive regulation of interleukin-15 biosynthetic process|up regulation of interleukin-15 production|positive regulation of IL-15 production										GO:0045374			biological_process											owl:Class	
GO:0015338	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050663	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051526	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001053	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016987	biolink:NamedThing	sigma factor activity	Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.	got7fsn_ti	plastid sigma factor activity|bacterial sigma factor activity|DNA-dependent RNA polymerase promoter selection factor|core DNA-dependent RNA polymerase binding promoter specificity activity|sigma factor activity|sigma transcription factor|promoter selection factor activity	https://github.com/geneontology/go-ontology/issues/14848|https://github.com/geneontology/go-ontology/issues/15587					krc	2010-08-11T04:12:24Z			GO:0000996|GO:0001053			molecular_function											owl:Class	
GO:0045877	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061021	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052292	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052109	biolink:NamedThing	obsolete induction by symbiont of defense-related host cell wall callose deposition	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	up regulation by symbiont of defense-related host cell wall callose deposition|positive regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|activation by symbiont of defense-related host cell wall callose deposition|upregulation by symbiont of defense-related host cell wall callose deposition|positive regulation by symbiont of defense-related host cell wall callose deposition|positive regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction|up-regulation by symbiont of defense-related host cell wall callose deposition|positive regulation by symbiont of defense-related host callose deposition|stimulation by symbiont of defense-related host cell wall callose deposition				This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052292|GO:0052291|GO:0052107			biological_process											owl:Class	
GO:0016599	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052101	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071578	biolink:NamedThing	zinc ion import across plasma membrane	The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	zinc II ion plasma membrane import|zinc II ion transmembrane import|zinc uptake|low-affinity zinc II ion transport|zinc ion transmembrane import|high-affinity zinc II ion transport|zinc import|high-affinity zinc II ion transmembrane import						jl	2010-01-28T02:22:02Z			GO:0006831|GO:0044749|GO:0006830|GO:0140160			biological_process											owl:Class	
GO:0006263	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008698	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030344	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072617	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006300	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042536	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072083	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051406	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043764	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008338	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009670	biolink:NamedThing	triose-phosphate:phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out).	got7fsn_ti	triose phosphate antiporter|dihydroxyacetone phosphate:phosphate antiporter activity|triose phosphate translocator|TPT										GO:0015122			molecular_function											owl:Class	
GO:0048250	biolink:NamedThing	iron import into the mitochondrion	The process in which iron is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti	mitochondrial iron ion transport|mitochondrial iron cation transmembrane transport|mitochondrial iron ion transmembrane transport|mitochondrial iron transport						al	2016-02-10T11:24:22Z			GO:1990925			biological_process											owl:Class	
GO:0016698	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904668	biolink:NamedThing	positive regulation of ubiquitin protein ligase activity	Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.	got7fsn_ti	upregulation of ubiquitin ligase activity|up-regulation of ubiquitin protein ligase activity|up-regulation of E3|positive regulation of protein ubiquitination activity|activation of APC-fizzy related complex activity|activation of ubiquitin protein ligase activity|activation of E3|up regulation of E3|up-regulation of ubiquitin ligase activity|up regulation of ubiquitin protein ligase activity|positive regulation of APC-fizzy related complex activity|upregulation of APC-fizzy related complex activity|activation of protein ubiquitination activity|activation of APC-Cdc20 complex activity|up regulation of ubiquitin ligase activity|up-regulation of APC-fizzy related complex activity|positive regulation of E3|up regulation of APC-fizzy related complex activity|up-regulation of protein ubiquitination activity|upregulation of protein ubiquitination activity|upregulation of ubiquitin protein ligase activity|activation of ubiquitin ligase activity|up regulation of protein ubiquitination activity|positive regulation of ubiquitin ligase activity|upregulation of E3|activation of anaphase-promoting complex activity						dph	2015-09-08T15:27:11Z			GO:1903835|GO:0051488|GO:0007092|GO:0090623			biological_process											owl:Class	
GO:0001749	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004480	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030461	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004036	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099152	biolink:NamedThing	regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane	Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.	got7fsn_ti							dos	2017-08-25T15:01:11Z						biological_process											owl:Class	
GO:0008858	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006992	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098705	biolink:NamedThing	copper ion import across plasma membrane	The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	copper cation import into cell|high affinity copper ion transport|high-affinity copper ion transport|high affinity copper transport|copper ion import into cell						mah	2014-04-03T13:26:04Z			GO:1902861|GO:0015678			biological_process											owl:Class	
GO:0003891	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016224	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018409	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048603	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043681	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042145	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044714	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007104	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150188	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031744	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019746	biolink:NamedThing	hopanoid biosynthetic process	The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.	got7fsn_ti	hopanoid synthesis|hopanoid anabolism|hopanoid biosynthesis|hopanoid formation													biological_process											owl:Class	
GO:0001904	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051714	biolink:NamedThing	positive regulation of cytolysis in other organism	Any process that activates or increases the frequency, rate or extent of the cytolysis by an organism of cells in another organism.	got7fsn_ti	up regulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another, non-host, organism|up-regulation of cytolysis of cells of another organism|stimulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another organism|activation of cytolysis of cells of another organism|upregulation of cytolysis of cells of another organism										GO:0001904			biological_process											owl:Class	
GO:0016000	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904621	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0085031	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010237	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045077	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032689	biolink:NamedThing	negative regulation of interferon-gamma production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.	got7fsn_ti	negative regulation of type II interferon production|down-regulation of interferon-gamma production|negative regulation of interferon-gamma biosynthetic process|down regulation of interferon-gamma production|downregulation of interferon-gamma production|negative regulation of interferon-gamma secretion|inhibition of interferon-gamma production										GO:0045077|GO:1902714			biological_process											owl:Class	
GO:0000360	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015581	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016195	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070969	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043809	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006831	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042507	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006095	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005067	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072612	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031187	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019259	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002245	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052301	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015646	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052556	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017132	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017048	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072509	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015936	biolink:NamedThing	coenzyme A metabolic process	The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	got7fsn_ti	coenzyme A metabolism|CoA metabolism										GO:0006763			biological_process											owl:Class	
GO:1990152	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051535	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030610	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017036	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006318	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019913	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005454	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048025	biolink:NamedThing	negative regulation of mRNA splicing, via spliceosome	Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.	got7fsn_ti	down-regulation of nuclear mRNA splicing via U2-type spliceosome|negative regulation of nuclear mRNA splicing via U2-type spliceosome|down regulation of nuclear mRNA splicing via U2-type spliceosome|down-regulation of nuclear mRNA splicing, via spliceosome|down regulation of nuclear mRNA splicing, via spliceosome|downregulation of nuclear mRNA splicing, via spliceosome|inhibition of nuclear mRNA splicing via U2-type spliceosome|negative regulation of pre-mRNA splicing|negative regulation of nuclear mRNA splicing, via spliceosome|downregulation of nuclear mRNA splicing via U2-type spliceosome|inhibition of nuclear mRNA splicing, via spliceosome										GO:0035056			biological_process											owl:Class	
GO:0150150	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072420	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072638	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045255	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097249	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005720	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102101	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004907	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061039	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019945	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006345	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903820	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046971	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000507	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007262	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033216	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035117	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043234	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000141	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098738	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044259	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060555	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099243	biolink:NamedThing	extrinsic component of synaptic membrane	The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti							dos	2017-05-25T17:24:23Z						cellular_component											owl:Class	
GO:0044699	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031206	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005288	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000483	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032717	biolink:NamedThing	negative regulation of interleukin-8 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production.	got7fsn_ti	down-regulation of interleukin-8 production|negative regulation of IL-8 production|downregulation of interleukin-8 production|inhibition of interleukin-8 production|negative regulation of interleukin-8 secretion|negative regulation of interleukin-8 biosynthetic process|down regulation of interleukin-8 production										GO:2000483|GO:0045415			biological_process											owl:Class	
GO:0008006	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052369	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007456	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006092	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046991	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035620	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006951	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048427	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009430	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098835	biolink:NamedThing	presynaptic endocytic zone membrane	The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release.	got7fsn_ti														cellular_component											owl:Class	
GO:1902861	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090484	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140242	biolink:NamedThing	translation at postsynapse	Translation that occurs at the postsynapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/210			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:26:27Z						biological_process											owl:Class	
GO:0001106	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060247	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016244	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016196	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099056	biolink:NamedThing	integral component of presynaptic membrane	The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral component of presynaptic plasma membrane													cellular_component											owl:Class	
GO:0044274	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015586	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098695	biolink:NamedThing	inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels	Any inositol 1,4,5-trisphosphate receptor activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	got7fsn_ti	IP3 receptor activity involved in regulation of postsynaptic cytosolic calcium levels						dos	2017-04-04T17:07:09Z						molecular_function											owl:Class	
GO:0048233	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043361	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902361	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006850	biolink:NamedThing	mitochondrial pyruvate transmembrane transport	The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti	pyruvate transmembrane transport in mitochondria|pyruvate membrane transport in mitochondrion|pyruvate membrane transport in mitochondria|mitochondrial pyruvate transport|pyruvate transmembrane transport in mitochondrion						dph	2013-08-15T11:19:35Z			GO:1902361			biological_process											owl:Class	
GO:1903809	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004524	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990369	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019353	biolink:NamedThing	protoporphyrinogen IX biosynthetic process from glutamate	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.	got7fsn_ti	protoporphyrinogen IX synthesis from glutamate|protoporphyrinogen IX formation from glutamate|protoporphyrinogen IX anabolism from glutamate													biological_process											owl:Class	
GO:0048474	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061012	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044670	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008862	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043142	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018692	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070882	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042520	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015071	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052565	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046746	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008723	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099033	biolink:NamedThing	anchored component of postsynaptic recycling endosome membrane	The component of the postsynaptic recycling endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0150043	biolink:NamedThing	structural constituent of synapse-associated extracellular matrix	The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.	got7fsn_ti	synapse-associated extracellular matrix structural constituent|extra-synaptic extracellular matrix structural constituent|structural constituent of extra-synaptic extracellular matrix						bc	2018-04-19T13:42:40Z						molecular_function											owl:Class	
GO:0072614	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044713	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016023	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008416	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007325	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051836	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003893	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032653	biolink:NamedThing	regulation of interleukin-10 production	Any process that modulates the frequency, rate, or extent of interleukin-10 production.	got7fsn_ti	regulation of interleukin-10 secretion|regulation of interleukin-10 biosynthetic process|regulation of IL-10 production										GO:0045074|GO:2001179			biological_process											owl:Class	
GO:0046770	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051226	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990552	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990550	biolink:NamedThing	mitochondrial alpha-ketoglutarate transmembrane transport	The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti	mitochondrial 2-oxoglutarate transmembrane transport						vw	2014-11-19T12:11:59Z			GO:1990552			biological_process											owl:Class	
GO:0035430	biolink:NamedThing	regulation of gluconate transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of gluconate membrane transport|regulation of gluconate transport						bf	2010-04-08T10:37:18Z			GO:0032893			biological_process											owl:Class	
GO:0009776	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102568	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001521	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009341	biolink:NamedThing	beta-galactosidase complex	A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.	got7fsn_ti														cellular_component											owl:Class	
GO:0031576	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000074	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052483	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035030	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045416	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990774	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098890	biolink:NamedThing	extrinsic component of postsynaptic membrane	The component of the postsynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0052262	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008601	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016924	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001085	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001021	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902825	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905647	biolink:NamedThing	proline import across plasma membrane	The directed movement of proline from outside of a cell into the cytoplasmic compartment.	got7fsn_ti	proline import into cell						mah	2014-03-31T13:14:04Z			GO:1902825			biological_process											owl:Class	
GO:0045206	biolink:NamedThing	obsolete MAPK phosphatase transporter activity	OBSOLETE. Enables the directed movement of MAPK phosphatase into, out of or within a cell, or between cells.	got7fsn_ti	MAPK phosphatase transporter activity|MKP shuttle|leptomycin B-sensitive MKP shuttle|leptomycin B-sensitive MAPK phosphatase transporter activity				This term was made obsolete because we do not know what it was intended to represent when it was created.					True	GO:0045207			molecular_function											owl:Class	
GO:0009796	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034449	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000004	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005605	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097638	biolink:NamedThing	L-arginine import across plasma membrane	The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	arginine import|L-arginine import into cell						tb	2012-09-24T14:28:58Z			GO:1902765|GO:0090467			biological_process											owl:Class	
GO:0002391	biolink:NamedThing	platelet activating factor production involved in inflammatory response	The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	platelet activating factor secretion|platelet activating factor secretion involved in inflammatory response|platelet activating factor production involved in acute inflammatory response|platelet activating factor production|platelet activating factor secretion involved in acute inflammatory response	https://github.com/geneontology/go-ontology/issues/20154									GO:0002390|GO:0002535|GO:0002392			biological_process											owl:Class	
GO:0007061	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006347	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001643	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008067	biolink:NamedThing	obsolete metabotropic glutamate, GABA-B-like receptor activity	OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the metabotropic glutamate receptor.	got7fsn_ti	metabotropic glutamate, GABA-B-like receptor activity|class C G-protein coupled receptor|class C orphan receptor activity|class C GPCR|class C G protein coupled receptor				This term was made obsolete because it represents a gene product and is named based on protein features.					True	GO:0001643|GO:0001645			molecular_function											owl:Class	
GO:1902713	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016449	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045941	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902440	biolink:NamedThing	protein localization to mitotic spindle pole body	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body.	got7fsn_ti	protein localisation in mitotic spindle pole body|protein localization in mitotic spindle pole body|protein localisation to mitotic spindle pole body|establishment of protein localization to mitotic spindle pole body						mah	2013-10-10T14:44:55Z			GO:1990975			biological_process											owl:Class	
GO:0021734	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044463	biolink:NamedThing	obsolete cell projection part	OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0042995				True				cellular_component											owl:Class	
GO:0010251	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003705	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016350	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046393	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001210	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043346	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045034	biolink:NamedThing	obsolete neuroblast division	OBSOLETE. The asymmetrical division of a neuroblast, the neural precursor in the central nervous system, giving rise to another neuroblast and a ganglion mother cell.	got7fsn_ti	neuroblast division|neuroblast division (sensu Vertebrata)|neuroblast division (sensu Nematoda and Protostomia)|neuroblast cell division				This term was made obsolete because the definition was incorrect. Not all neuroblasts divide asymmetrically. Neuroblasts give rise to neurons after division.					True	GO:0043345|GO:0043346			biological_process											owl:Class	
GO:0070683	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045082	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904359	biolink:NamedThing	regulation of spore germination	Any process that modulates the frequency, rate or extent of spore germination.	got7fsn_ti	modulation of spore germination on or near host						pf	2015-06-12T19:46:06Z			GO:0075006			biological_process											owl:Class	
GO:0042456	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008606	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008896	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050715	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902778	biolink:NamedThing	response to alkane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.	got7fsn_ti	process resulting in tolerance to alkane										GO:1990373			biological_process											owl:Class	
GO:0090457	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090513	biolink:NamedThing	L-histidine transmembrane import into vacuole	The directed movement of L-histidine into the vacuole across the vacuolar membrane.	got7fsn_ti	vacuolar histidine import|histidine transmembrane import into vacuole						tb	2012-12-14T11:25:52Z			GO:0090457			biological_process											owl:Class	
GO:0015906	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072600	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004884	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001158	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072447	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099144	biolink:NamedThing	anchored component of synaptic membrane	The component of the synaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti							dos	2017-05-25T17:25:19Z						cellular_component											owl:Class	
GO:0005101	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051689	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043222	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016194	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032863	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007243	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002375	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005830	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045079	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006652	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044464	biolink:NamedThing	obsolete cell part	OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms.	got7fsn_ti	protoplast|cellular subcomponent				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	CL:0000000				True		NIF_Subcellular:sao628508602		cellular_component											owl:Class	
GO:0097024	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018917	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044401	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051183	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007001	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015290	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008624	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045412	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016766	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004041	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050719	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045403	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045845	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016097	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050375	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016523	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015058	biolink:NamedThing	obsolete epidermal growth factor-like module containing hormone receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	epidermal growth factor-like module containing hormone receptor activity|EGF-like module containing hormone receptor activity|Egr1 hormone receptor				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True	GO:0016523			molecular_function											owl:Class	
GO:0016249	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046846	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042936	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010302	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005232	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043340	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901138	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GOP:chebi_ph7_3	biolink:NamedThing			got7fsn_ti					Rhea list of ChEBI terms representing the major species at pH 7.3.																				owl:AnnotationProperty	
GO:0044368	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102609	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007184	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044366	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004302	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042872	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150156	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048551	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044432	biolink:NamedThing	obsolete endoplasmic reticulum part	OBSOLETE. Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.	got7fsn_ti	ER component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005783				True				cellular_component											owl:Class	
GO:0044442	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044441	biolink:NamedThing	obsolete ciliary part	OBSOLETE. Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.	got7fsn_ti	flagellum part|cilial part|flagellum component|flagellar part|microtubule-based flagellum part|cilium part				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. Also note that cilia and eukaryotic flagella are deemed to be equivalent.	GO:0005929				True	GO:0044442			cellular_component											owl:Class	
GO:0042828	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007326	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010708	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046906	biolink:NamedThing	tetrapyrrole binding	Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.	got7fsn_ti	porphyrin binding													molecular_function											owl:Class	
GO:1902540	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901243	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016294	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048186	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090155	biolink:NamedThing	negative regulation of sphingolipid biosynthetic process	Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	got7fsn_ti	negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis						tb	2009-12-08T03:33:39Z			GO:0090157			biological_process											owl:Class	
GO:0051807	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905659	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044006	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005062	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075238	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016953	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010993	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072455	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006395	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015659	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0103052	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090526	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006111	biolink:NamedThing	regulation of gluconeogenesis	Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.	got7fsn_ti	regulation of gluconeogenesis involved in cellular glucose homeostasis|regulation of glucose biosynthetic process|regulation of glucose biosynthesis						tb	2013-01-18T12:47:43Z			GO:0090526			biological_process											owl:Class	
GO:0102260	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046744	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015502	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019968	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044152	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0039676	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042107	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099240	biolink:NamedThing	intrinsic component of synaptic membrane	The component of the synaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to synaptic membrane						dos	2017-05-25T17:23:21Z						cellular_component											owl:Class	
GO:0007335	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001078	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990296	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007404	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019109	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015992	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030914	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000361	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048042	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000029	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015365	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045417	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048253	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043147	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0055133	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900172	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071845	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072404	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099092	biolink:NamedThing	postsynaptic density, intracellular component	A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.	got7fsn_ti														cellular_component											owl:Class	
GO:0043790	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005453	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005468	biolink:NamedThing	obsolete small-molecule carrier or transporter	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	small-molecule carrier or transporter				This term was made obsolete because it does not provide a useful functional classification.	GO:0005215				True	GO:0005454|GO:0005453			molecular_function											owl:Class	
GO:0000996	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902520	biolink:NamedThing	response to doxorubicin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:44:13Z						biological_process											owl:Class	
GO:0051856	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017160	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902150	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035734	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072569	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905965	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001600	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006519	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016400	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070872	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099550	biolink:NamedThing	trans-synaptic signaling, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0046748	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098993	biolink:NamedThing	anchored component of synaptic vesicle membrane	The component of the synaptic vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0019965	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003946	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008032	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008680	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006966	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015411	biolink:NamedThing	ABC-type taurine transporter transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in).	got7fsn_ti	taurine-transporting ATPase activity|taurine ABC transporter|ATPase-coupled taurine transporter activity|ATP-dependent taurine transporter activity	https://github.com/geneontology/go-ontology/issues/21640										MetaCyc:ABC-64-RXN|RHEA:14613|EC:7.6.2.7|MetaCyc:3.6.3.36-RXN		molecular_function											owl:Class	
GO:0003699	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043091	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030333	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045413	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072459	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015222	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000778	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002640	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0080039	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015235	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072641	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034259	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903758	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052566	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010577	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007322	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046616	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043167	biolink:NamedThing	ion binding	Binding to an ion, a charged atoms or groups of atoms.	got7fsn_ti	atom binding													molecular_function											owl:Class	
GO:0019850	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018932	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900041	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098923	biolink:NamedThing	retrograde trans-synaptic signaling by soluble gas	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand.	got7fsn_ti														biological_process											owl:Class	
GO:0001041	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016431	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032512	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044461	biolink:NamedThing	obsolete bacterial-type flagellum part	OBSOLETE. Any constituent part of the bacterial-type flagellum, a 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by a transmembrane ion potential, typically a proton or sodium potential.	got7fsn_ti	flagellin-based flagellum part				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009288				True				cellular_component											owl:Class	
GO:0005974	biolink:NamedThing	obsolete fibrinogen gamma chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	fibrinogen gamma chain				This term was made obsolete because it represents a single gene product and not a complex.	GO:0005577				True	GO:0008007			cellular_component											owl:Class	
GO:0003760	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000942	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902706	biolink:NamedThing	hexose catabolic process to acetate	The chemical reactions and pathways resulting in the breakdown of hexose to acetate.	got7fsn_ti	hexose degradation to acetate|acidogenesis|hexose breakdown to acetate|hexose catabolism to acetate						tb	2014-02-19T18:43:23Z			GO:1990286			biological_process											owl:Class	
GO:0022817	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008183	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000356	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042530	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048141	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006645	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072510	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045376	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015202	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098667	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061166	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051372	biolink:NamedThing			got7fsn_ti										True															owl:Class	
NCBITaxon:6237	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0036271	biolink:NamedThing	response to methylphenidate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.	got7fsn_ti	response to ritalin|response to MPH|response to MPD				Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T01:30:57Z						biological_process											owl:Class	
GO:0009021	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032403	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045420	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032643	biolink:NamedThing	regulation of connective tissue growth factor production	Any process that modulates the frequency, rate, or extent of connective tissue growth factor production.	got7fsn_ti	regulation of Hcs24 production|regulation of IGFBP8 production|regulation of CTGF production|regulation of connective tissue growth factor biosynthetic process|regulation of Fisp12 production|regulation of hypertrophic chondrocyte-specific gene product 24 production|regulation of CCN2 production										GO:0045420			biological_process											owl:Class	
GO:0009287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002422	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015379	biolink:NamedThing	potassium:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).	got7fsn_ti	potassium ion symporter activity										GO:0022820	Reactome:R-HSA-426155|Reactome:R-HSA-5623806		molecular_function											owl:Class	
GO:0052533	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019537	biolink:NamedThing	vibriobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae.	got7fsn_ti	vibriobactin synthesis|vibriobactin biosynthetic process, peptide modification|vibriobactin biosynthesis|vibriobactin formation|vibriobactin anabolism|vibriobactin biosynthetic process, peptide formation										GO:0031195|GO:0031196			biological_process											owl:Class	
GO:0042505	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042231	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0055134	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004199	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030693	biolink:NamedThing	obsolete caspase activity	OBSOLETE. Catalysis of the hydrolysis of a peptide bond on the carboxyl side of an aspartate residue.	got7fsn_ti	caspase-6 activity|effector caspase activity|caspase-4 activity|caspase activity|caspase-9 activity|signaling (initiator) caspase activity|caspase-7 activity|caspase-2 activity|caspase-1 activity|caspase-10 activity|caspase-8 activity|caspase-5 activity|caspase-3 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True	GO:0004199			molecular_function											owl:Class	
GO:0009031	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0055128	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006866	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005486	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018176	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099055	biolink:NamedThing	integral component of postsynaptic membrane	The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0005100	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000173	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042525	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032748	biolink:NamedThing	positive regulation of interleukin-24 production	Any process that activates or increases the frequency, rate, or extent of interleukin-24 production.	got7fsn_ti	positive regulation of IL-24 production|activation of interleukin-24 production|up regulation of interleukin-24 production|upregulation of interleukin-24 production|stimulation of interleukin-24 production|positive regulation of interleukin-24 biosynthetic process|up-regulation of interleukin-24 production										GO:0045536			biological_process											owl:Class	
GO:0015784	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042097	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032855	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009369	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008249	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004762	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045790	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044447	biolink:NamedThing	obsolete axoneme part	OBSOLETE. Any constituent part of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.	got7fsn_ti	axonemal part				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. Also note that cilia and eukaryotic flagella are deemed to be equivalent.	GO:0005930				True				cellular_component											owl:Class	
GO:0098961	biolink:NamedThing	dendritic transport of ribonucleoprotein complex	The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.	got7fsn_ti	dendritic transport of RNP complex													biological_process											owl:Class	
GO:0072652	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046715	biolink:NamedThing	active borate transmembrane transporter activity	Enables the transport of borate across a membrane against the concentration gradient.	got7fsn_ti	boron uptake transmembrane transporter activity|efflux-type borate transporter|efflux-type boron transporter|borate uptake transmembrane transporter activity|boron transmembrane transporter activity|borate transmembrane transporter activity						dhl	2009-05-19T04:09:56Z			GO:0080138			molecular_function											owl:Class	
GO:0048125	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150054	biolink:NamedThing	regulation of postsynaptic neurotransmitter receptor diffusion trapping	Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping.	got7fsn_ti							bc	2018-05-10T14:26:59Z						biological_process											owl:Class	
GO:0042238	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904623	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0120081	biolink:NamedThing	obsolete positive regulation of microfilament motor activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of microfilament motor activity.	got7fsn_ti	positive regulation of myosin ATPase activity|positive regulation of actin-activated ATPase activity|positive regulation of actin-filament motor activity|positive regulation of actin filament motor activity|activation of actin-dependent ATPase activity|positive regulation of actin-dependent ATPase activity|positive regulation of muscle motor activity|activation of actin-activated ATPase activity|upregulation of actin-dependent ATPase activity	https://github.com/geneontology/go-ontology/issues/20877|https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140660	krc	2017-07-05T21:48:56Z		True	GO:1904623			biological_process											owl:Class	
GO:0044765	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031196	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045526	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003826	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045440	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050720	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098894	biolink:NamedThing	extrinsic component of presynaptic endocytic zone membrane	The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0043355	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005218	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042977	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017115	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000391	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036281	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044115	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004188	biolink:NamedThing	obsolete serine-type Pro-X carboxypeptidase activity	OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a serine-type peptidase mechanism to release a C-terminal amino acid.	got7fsn_ti	proline carboxypeptidase activity|serine-type Pro-X carboxypeptidase activity|peptidylprolylamino acid carboxypeptidase activity|proline-specific carboxypeptidase P|lysosomal Pro-X carboxypeptidase activity|lysosomal Pro-Xaa carboxypeptidase activity|prolyl carboxypeptidase activity|lysosomal carboxypeptidase C activity|aminoacylproline carboxypeptidase activity|angiotensinase C activity|PCP			GO:0004185	This term was made obsolete because it represents a gene product.					True	GO:0008323			molecular_function											owl:Class	
GO:0008372	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150126	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905121	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045867	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043018	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046388	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072407	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033218	biolink:NamedThing	amide binding	Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.	got7fsn_ti														molecular_function											owl:Class	
GO:0015028	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008827	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903765	biolink:NamedThing	negative regulation of potassium ion export across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane.	got7fsn_ti	inhibition of potassium export|downregulation of potassium ion export across plasma membrane|inhibition of potassium ion export across plasma membrane|inhibition of potassium ion export|down regulation of potassium ion export|down-regulation of potassium ion export across plasma membrane|negative regulation of potassium ion export|negative regulation of potassium export|down-regulation of potassium export|down-regulation of potassium ion export|down regulation of potassium export|downregulation of potassium export|down regulation of potassium ion export across plasma membrane|downregulation of potassium ion export						rl	2013-07-17T16:40:02Z			GO:1902303			biological_process											owl:Class	
GO:0090699	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905539	biolink:NamedThing	regulation of postsynapse to nucleus signaling pathway	Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway.	got7fsn_ti	regulation of postsynaptic signaling to nucleus						dos	2016-10-07T17:03:38Z						biological_process											owl:Class	
GO:1903989	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015656	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042109	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050716	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032732	biolink:NamedThing	positive regulation of interleukin-1 production	Any process that activates or increases the frequency, rate, or extent of interleukin-1 production.	got7fsn_ti	up regulation of interleukin-1 production|up-regulation of interleukin-1 production|positive regulation of interleukin-1 secretion|positive regulation of interleukin-1 biosynthetic process|stimulation of interleukin-1 production|upregulation of interleukin-1 production|activation of interleukin-1 production|positive regulation of IL-1 production										GO:0045362|GO:0050716			biological_process											owl:Class	
GO:0030609	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042683	biolink:NamedThing	negative regulation of compound eye cone cell fate specification	Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.	got7fsn_ti	down-regulation of cone cell fate specification|down regulation of cone cell fate specification|inhibition of cone cell fate specification|suppression of cone cell fate|downregulation of cone cell fate specification										GO:0010000			biological_process											owl:Class	
GO:0140237	biolink:NamedThing	translation at presynapse, modulating chemical synaptic transmission	Translation that occurs at the presynapse, and that modulates chemical synaptic transmission.	got7fsn_ti		https://github.com/geneontology/synapse/issues/216			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-13T13:07:23Z						biological_process											owl:Class	
GO:0099057	biolink:NamedThing	integral component of presynaptic endocytic zone membrane	The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0048272	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000058	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000056	biolink:NamedThing	ribosomal small subunit export from nucleus	The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.	got7fsn_ti	ribosomal small subunit export from cell nucleus|ribosomal small subunit transport from nucleus to cytoplasm|ribosomal small subunit export out of nucleus|40S ribosomal subunit export from nucleus|30S ribosomal subunit export from nucleus|ribosomal small subunit-nucleus export										GO:0000058			biological_process											owl:Class	
GO:0102017	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0047767	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005098	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002214	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044021	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052282	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052202	biolink:NamedThing	obsolete negative regulation by symbiont of defense-related host cell wall callose deposition	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	downregulation by symbiont of defense-related host cell wall callose deposition|negative regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction|inhibition by symbiont of defense-related host cell wall callose deposition|negative regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|down regulation by symbiont of defense-related host cell wall callose deposition|down-regulation by symbiont of defense-related host cell wall callose deposition|negative regulation by symbiont of defense-related host callose deposition				This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052282|GO:0052087|GO:0052311			biological_process											owl:Class	
GO:0009259	biolink:NamedThing	ribonucleotide metabolic process	The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	ribonucleotide metabolism										GO:0009121			biological_process											owl:Class	
GO:0031191	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010553	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033225	biolink:NamedThing	ATPase-coupled 2-aminoethylphosphonate transporter activity	Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in).	got7fsn_ti	2-aminoethylphosphonate transporting ATPase activity|2-phosphonoethylamine transmembrane transporter activity|ciliatine transportingATPase activity|2-phosphonoethylamine transporting ATPase activity|2-aminoethylphosphonate transmembrane transporter activity|ATP-dependent 2-aminoethylphosphonate transporter activity|2-aminoethylphosphonate-transporting ATPase activity|ciliatine transporter activity				There is no annotated example of this MF; therefore we cannot classify it more precisely.						GO:0033224	RHEA:32775		molecular_function											owl:Class	
GO:0015245	biolink:NamedThing	fatty acid transmembrane transporter activity	Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.	got7fsn_ti	fatty acyl transporter activity|fatty-acyl group transporter activity|peroxisomal fatty acyl transporter|fatty acid transporter activity										GO:0015246	Reactome:R-HSA-5627891|Reactome:R-HSA-879585		molecular_function											owl:Class	
GO:0005040	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904167	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006160	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001146	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030966	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075710	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030646	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017100	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048365	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052099	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0038044	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044252	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902478	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900425	biolink:NamedThing	negative regulation of defense response to bacterium	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.	got7fsn_ti	negative regulation of defense response to bacterium, incompatible interaction|downregulation of defense response to bacterium|negative regulation of defence response to bacteria|inhibition of defence response to bacteria|inhibition of defense response to bacterium|down-regulation of defense response to bacteria|down-regulation of defense response to bacterium|down-regulation of defence response to bacterium|inhibition of defence response to pathogenic bacterium, incompatible interaction|down-regulation of defence response to bacteria|down regulation of defense response to bacteria|inhibition of resistance response to pathogenic bacteria|inhibition of defence response to bacterium|downregulation of defence response to bacterium|down regulation of defense response to bacterium|downregulation of defense response to bacteria|downregulation of defence response to bacteria|inhibition of response to pathogenic bacterium (incompatible interaction)|inhibition of defense response to bacterium, incompatible interaction|down regulation of antibacterial peptide activity|inhibition of defense response to bacteria|inhibition of resistance response to pathogenic bacterium|down regulation of defence response to bacterium|inhibition of antibacterial peptide activity|negative regulation of defense response to bacteria|down regulation of defence response to bacteria|inhibition of defence response to pathogenic bacteria, incompatible interaction|down-regulation of antibacterial peptide activity|downregulation of antibacterial peptide activity|negative regulation of defence response to bacterium|inhibition of response to pathogenic bacteria (incompatible interaction)|negative regulation of antibacterial peptide activity						dhl	2012-04-24T10:12:54Z			GO:1902478			biological_process											owl:Class	
GO:0015177	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072425	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032699	biolink:NamedThing	negative regulation of interleukin-16 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production.	got7fsn_ti	negative regulation of interleukin-16 biosynthetic process|downregulation of interleukin-16 production|negative regulation of IL-16 production|inhibition of interleukin-16 production|down-regulation of interleukin-16 production|down regulation of interleukin-16 production										GO:0045376			biological_process											owl:Class	
GO:0150130	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099165	biolink:NamedThing	postsynaptic specialization of symmetric synapse, intracellular component	A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.  This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses.	got7fsn_ti							dos	2017-09-10T11:54:15Z						cellular_component											owl:Class	
GO:0042002	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044462	biolink:NamedThing	obsolete external encapsulating structure part	OBSOLETE. Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria).	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0030312				True				cellular_component											owl:Class	
GO:0006344	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0080080	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007513	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009552	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006461	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032864	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902149	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902147	biolink:NamedThing	regulation of response to cytokinesis checkpoint signaling	Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling.	got7fsn_ti	regulation of response to signal involved in cytokinesis checkpoint|regulation of cytokinesis checkpoint effector process						jl	2013-05-21T15:43:53Z			GO:1902149			biological_process											owl:Class	
GO:1905120	biolink:NamedThing	cellular response to haloperidol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2016-04-08T12:36:47Z						biological_process											owl:Class	
GO:0098587	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044723	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003742	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042033	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031988	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015318	biolink:NamedThing	inorganic molecular entity transmembrane transporter activity	Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.	got7fsn_ti	inorganic solute uptake transmembrane transporter activity|inorganic uptake permease activity	https://github.com/geneontology/go-ontology/issues/14372												molecular_function											owl:Class	
GO:0098963	biolink:NamedThing	dendritic transport of messenger ribonucleoprotein complex	The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites.	got7fsn_ti	dendritic transport of mRNA RNP complex													biological_process											owl:Class	
GO:0000799	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044704	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071776	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052068	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900390	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034756	biolink:NamedThing	regulation of iron ion transport	Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of iron transport|regulation of iron import|regulation of iron ion import|regulation of Fe transport						mah	2012-04-18T04:00:14Z			GO:1900390			biological_process											owl:Class	
GO:0008072	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900173	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003354	biolink:NamedThing	negative regulation of cilium movement	Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.	got7fsn_ti	negative regulation of microtubule-based flagellum movement|negative regulation of flagellum movement				Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-12-03T10:17:47Z			GO:1900173			biological_process											owl:Class	
GO:0070110	biolink:NamedThing	ciliary neurotrophic factor receptor complex	A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.	got7fsn_ti														cellular_component											owl:Class	
GO:0120015	biolink:NamedThing	sterol transfer activity	Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	sterol carrier activity|intermembrane sterol transfer activity	https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-17T03:46:28Z						molecular_function											owl:Class	
GO:0014905	biolink:NamedThing	myoblast fusion involved in skeletal muscle regeneration	A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:1903000	biolink:NamedThing	regulation of lipid transport across blood-brain barrier	Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.	got7fsn_ti	regulation of lipid transport across blood brain barrier						sjp	2014-05-09T09:30:04Z						biological_process											owl:Class	
GO:0110162	biolink:NamedThing	regulation of mitotic spindle elongation (spindle phase three)	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three).	got7fsn_ti							kmv	2019-08-12T15:26:01Z						biological_process											owl:Class	
GO:0016345	biolink:NamedThing	female meiotic chromosome movement towards spindle pole	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis.	got7fsn_ti	female meiotic chromosome movement|female meiotic chromosome movement to spindle pole|chromosome movement towards spindle pole during female meiosis													biological_process											owl:Class	
GO:1903201	biolink:NamedThing	regulation of oxidative stress-induced cell death	Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death.	got7fsn_ti	regulation of cell death in response to oxidative stress						bf	2014-07-21T16:10:30Z						biological_process											owl:Class	
GO:0015105	biolink:NamedThing	arsenite transmembrane transporter activity	Enables the transfer of arsenite from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0045943	biolink:NamedThing	positive regulation of transcription by RNA polymerase I	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I.	got7fsn_ti	activation of transcription from RNA polymerase I promoter|up-regulation of transcription from RNA polymerase I promoter|stimulation of transcription from RNA polymerase I promoter|positive regulation of transcription from RNA polymerase I promoter|up regulation of transcription from RNA polymerase I promoter|positive regulation of transcription from Pol I promoter|upregulation of transcription from RNA polymerase I promoter													biological_process											owl:Class	
GO:0099049	biolink:NamedThing	clathrin coat assembly involved in endocytosis	The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation.	got7fsn_ti														biological_process											owl:Class	
GO:0098906	biolink:NamedThing	regulation of Purkinje myocyte action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti							tb	2011-11-10T08:58:56Z						biological_process											owl:Class	
GO:2000590	biolink:NamedThing	negative regulation of metanephric mesenchymal cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration.	got7fsn_ti	negative regulation of metanephric mesenchyme chemotaxis						bf	2011-04-07T03:29:49Z						biological_process											owl:Class	
GO:0033221	biolink:NamedThing	ATPase-coupled urea transmembrane transporter activity	Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in).	got7fsn_ti	urea-transporting ATPase activity|carbamide-transporting ATPase activity|ATP-dependent urea transmembrane transporter activity											RHEA:32803		molecular_function											owl:Class	
GO:0071918	biolink:NamedThing	urea transmembrane transport	The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	urea membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-09-24T10:41:36Z						biological_process											owl:Class	
GO:0071231	biolink:NamedThing	cellular response to folic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.	got7fsn_ti	response to folate|response to vitamin B9						mah	2009-12-03T02:08:32Z						biological_process											owl:Class	
GO:0071329	biolink:NamedThing	cellular response to sucrose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.	got7fsn_ti							mah	2009-12-10T05:31:22Z						biological_process											owl:Class	
GO:1904175	biolink:NamedThing	positive regulation of histone demethylase activity (H3-K4 specific)	Any process that activates or increases the frequency, rate or extent of histone demethylase activity (H3-K4 specific).	got7fsn_ti	up regulation of histone demethylase activity (H3-K4 specific)|upregulation of histone demethylase activity (H3-K4 specific)|activation of histone demethylase activity (H3-K4 specific)|up-regulation of histone demethylase activity (H3-K4 specific)						dph	2015-04-24T19:29:45Z						biological_process											owl:Class	
GO:0042479	biolink:NamedThing	positive regulation of eye photoreceptor cell development	Any process that activates or increases the frequency, rate or extent of eye photoreceptor development.	got7fsn_ti	stimulation of eye photoreceptor cell development|upregulation of eye photoreceptor cell development|up regulation of eye photoreceptor cell development|activation of eye photoreceptor cell development|positive regulation of eye photoreceptor development|up-regulation of eye photoreceptor cell development													biological_process											owl:Class	
GO:1901551	biolink:NamedThing	negative regulation of endothelial cell development	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development.	got7fsn_ti	down regulation of endothelial cell development|down-regulation of endothelial cell development|downregulation of endothelial cell development|inhibition of endothelial cell development						pr	2012-10-30T12:59:54Z						biological_process											owl:Class	
GO:0033300	biolink:NamedThing	dehydroascorbic acid transmembrane transporter activity	Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other.	got7fsn_ti	dehydroascorbic acid transporter activity|dehydroascorbate transporter activity											RHEA:60380|Reactome:R-HSA-198818		molecular_function											owl:Class	
GO:1905620	biolink:NamedThing	negative regulation of alpha-(1->3)-fucosyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.	got7fsn_ti	down-regulation of alpha-1,3-fucosyltransferase activity|negative regulation of alpha(1,3)-fucosyltransferase activity|negative regulation of alpha-(1,3)-fucosyltransferase activity|inhibition of alpha(1,3)-fucosyltransferase activity|down regulation of alpha-(1,3)-fucosyltransferase activity|down regulation of alpha-(1->3)-fucosyltransferase activity|down regulation of alpha(1,3)-fucosyltransferase activity|inhibition of alpha-(1->3)-fucosyltransferase activity|inhibition of alpha-1,3-fucosyltransferase activity|down-regulation of alpha-(1,3)-fucosyltransferase activity|down regulation of alpha-1,3-fucosyltransferase activity|down-regulation of alpha(1,3)-fucosyltransferase activity|downregulation of alpha-(1->3)-fucosyltransferase activity|downregulation of alpha-1,3-fucosyltransferase activity|inhibition of alpha-(1,3)-fucosyltransferase activity|down-regulation of alpha-(1->3)-fucosyltransferase activity|negative regulation of alpha-1,3-fucosyltransferase activity|downregulation of alpha(1,3)-fucosyltransferase activity|downregulation of alpha-(1,3)-fucosyltransferase activity						rz	2016-10-28T14:39:45Z						biological_process											owl:Class	
GO:0001931	biolink:NamedThing	uropod	A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.	got7fsn_ti	uropodium|retractile pole|distal pole complex													cellular_component											owl:Class	
GO:1901040	biolink:NamedThing	negative regulation of peptide antigen transport	Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport.	got7fsn_ti	inhibition of peptide antigen transport|downregulation of peptide antigen transport|down regulation of peptide antigen transport|down-regulation of peptide antigen transport						bf	2012-06-22T04:08:18Z						biological_process											owl:Class	
GO:1904718	biolink:NamedThing	negative regulation of AMPA glutamate receptor clustering	Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering.	got7fsn_ti	inhibition of AMPA glutamate receptor clustering|down regulation of AMPA glutamate receptor clustering|inhibition of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|negative regulation of AMPA receptor clustering|downregulation of AMPA glutamate receptor clustering|downregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|inhibition of AMPA receptor clustering|negative regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|downregulation of AMPA receptor clustering|down-regulation of AMPA receptor clustering|down regulation of AMPA receptor clustering|down regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down-regulation of AMPA glutamate receptor clustering						hjd	2015-10-07T19:32:28Z						biological_process											owl:Class	
GO:0072107	biolink:NamedThing	positive regulation of ureteric bud formation	Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.	got7fsn_ti							mah	2010-02-12T02:37:28Z						biological_process											owl:Class	
GO:0002631	biolink:NamedThing	regulation of granuloma formation	Any process that modulates the frequency, rate, or extent of granuloma formation.	got7fsn_ti														biological_process											owl:Class	
GO:0050544	biolink:NamedThing	arachidonic acid binding	Binding to arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.	got7fsn_ti	arachidonate binding													molecular_function											owl:Class	
GO:0015759	biolink:NamedThing	beta-glucoside transport	The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.	got7fsn_ti														biological_process											owl:Class	
GO:0015545	biolink:NamedThing	bicyclomycin transmembrane transporter activity	Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.	got7fsn_ti	bicyclomycin transporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0015905	biolink:NamedThing	bicyclomycin transmembrane transport	The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.	got7fsn_ti	bicyclomycin transport													biological_process											owl:Class	
GO:2000373	biolink:NamedThing	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.	got7fsn_ti	positive regulation of DNA topoisomerase IV activity|positive regulation of DNA topoisomerase (ATP-hydrolysing)|positive regulation of deoxyribonucleate topoisomerase|positive regulation of topoisomerase II|positive regulation of DNA topoisomerase II|positive regulation of type II DNA topoisomerase activity|positive regulation of DNA topoisomerase type II activity|positive regulation of topoisomerase|positive regulation of deoxyribonucleic topoisomerase activity						mah	2011-02-09T02:35:43Z						biological_process											owl:Class	
GO:0042220	biolink:NamedThing	response to cocaine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.	got7fsn_ti														biological_process											owl:Class	
GO:1990862	biolink:NamedThing	nuclear membrane complex Bqt3-Bqt4	A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4.	got7fsn_ti							al	2015-09-25T12:14:28Z						cellular_component											owl:Class	
GO:0005639	biolink:NamedThing	integral component of nuclear inner membrane	The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to nuclear inner membrane													cellular_component											owl:Class	
GO:1903384	biolink:NamedThing	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.	got7fsn_ti	inhibition of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|negative regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|negative regulation of neuron apoptosis in response to hydrogen peroxide|protection against hydrogen peroxide-induced neuron apoptosis|down regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|downregulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|down-regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|down regulation of neuron apoptosis in response to hydrogen peroxide|down-regulation of neuron apoptosis in response to hydrogen peroxide|protection against H2O2-induced neuron apoptosis|negative regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|down-regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of neuron apoptosis in response to hydrogen peroxide|inhibition of neuron intrinsic apoptotic signaling pathway in response to H2O2|downregulation of neuron apoptosis in response to hydrogen peroxide|downregulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|down regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of H2O2-induced neuron intrinsic apoptotic signaling pathway|down-regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway						bf	2014-08-27T08:50:45Z						biological_process											owl:Class	
GO:0045693	biolink:NamedThing	positive regulation of embryo sac central cell differentiation	Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation.	got7fsn_ti	positive regulation of female gametophyte central cell differentiation|activation of female gametophyte central cell differentiation|up regulation of female gametophyte central cell differentiation|stimulation of female gametophyte central cell differentiation|up-regulation of female gametophyte central cell differentiation|upregulation of female gametophyte central cell differentiation													biological_process											owl:Class	
GO:0051958	biolink:NamedThing	methotrexate transport	The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.	got7fsn_ti														biological_process											owl:Class	
GO:1901477	biolink:NamedThing	benomyl transmembrane transport	The directed movement of benomyl across a membrane.	got7fsn_ti	benomyl membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2012-10-04T23:11:36Z						biological_process											owl:Class	
GO:0090173	biolink:NamedThing	regulation of synaptonemal complex assembly	Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.	got7fsn_ti							tb	2009-12-11T11:40:36Z						biological_process											owl:Class	
GO:1900264	biolink:NamedThing	positive regulation of DNA-directed DNA polymerase activity	Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity.	got7fsn_ti	up regulation of iota DNA polymerase activity|upregulation of zeta DNA polymerase activity|activation of DNA polymerase gamma|upregulation of lambda DNA polymerase activity|positive regulation of deoxyribonucleic duplicase activity|upregulation of deoxyribonucleic duplicase activity|up-regulation of DNA-directed DNA polymerase activity|up-regulation of eta DNA polymerase activity|positive regulation of DNA polymerase gamma|upregulation of Tca DNA polymerase|positive regulation of DNA polymerase beta|up regulation of DNA polymerase III|upregulation of kappa DNA polymerase activity|positive regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|up-regulation of DNA replicase activity|activation of beta DNA polymerase activity|activation of sigma DNA polymerase activity|activation of Taq Pol I|up-regulation of sigma DNA polymerase activity|up regulation of DNA duplicase activity|upregulation of sigma DNA polymerase activity|positive regulation of DNA duplicase activity|activation of eta DNA polymerase activity|activation of gamma DNA-directed DNA polymerase activity|up-regulation of zeta DNA polymerase activity|up regulation of deoxyribonucleic polymerase I|activation of DNA polymerase III|upregulation of Taq DNA polymerase|up-regulation of Taq DNA polymerase|positive regulation of Taq Pol I|up-regulation of epsilon DNA polymerase activity|up-regulation of deoxyribonucleic duplicase activity|upregulation of DNA polymerase alpha|activation of DNA polymerase alpha|activation of DNA polymerase V activity|upregulation of duplicase|activation of deoxyribonucleic polymerase I|positive regulation of gamma DNA-directed DNA polymerase activity|activation of DNA-directed DNA polymerase activity|upregulation of DNA polymerase III|positive regulation of Tca DNA polymerase|activation of DNA duplicase activity|upregulation of DNA-dependent DNA polymerase activity|up regulation of kappa DNA polymerase activity|up-regulation of gamma DNA-directed DNA polymerase activity|positive regulation of DNA nucleotidyltransferase (DNA-directed) activity|upregulation of alpha DNA polymerase activity|positive regulation of iota DNA polymerase activity|up regulation of deoxyribonucleic acid duplicase activity|up regulation of theta DNA polymerase activity|up regulation of DNA polymerase beta|activation of DNA polymerase II|upregulation of sequenase|upregulation of delta DNA polymerase activity|positive regulation of zeta DNA polymerase activity|activation of nu DNA polymerase activity|upregulation of DNA nucleotidyltransferase (DNA-directed) activity|positive regulation of duplicase|upregulation of DNA polymerase beta|up-regulation of alpha DNA polymerase activity|activation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|up-regulation of Tca DNA polymerase|up regulation of beta DNA polymerase activity|up-regulation of DNA polymerase alpha|positive regulation of sequenase|activation of iota DNA polymerase activity|positive regulation of mu DNA polymerase activity|upregulation of Klenow fragment|up regulation of Klenow fragment|up-regulation of DNA-dependent DNA polymerase activity|up regulation of mu DNA polymerase activity|upregulation of DNA polymerase gamma|positive regulation of theta DNA polymerase activity|up-regulation of DNA polymerase gamma|up-regulation of DNA polymerase II|upregulation of DNA-directed DNA polymerase activity|upregulation of DNA polymerase V activity|up-regulation of kappa DNA polymerase activity|upregulation of theta DNA polymerase activity|activation of delta DNA polymerase activity|up regulation of DNA polymerase I|activation of Klenow fragment|positive regulation of Taq DNA polymerase|up-regulation of delta DNA polymerase activity|up regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|up regulation of DNA polymerase II|activation of duplicase|upregulation of gamma DNA-directed DNA polymerase activity|positive regulation of delta DNA polymerase activity|up-regulation of DNA polymerase beta|up regulation of zeta DNA polymerase activity|activation of DNA polymerase beta|up regulation of DNA polymerase V activity|positive regulation of nu DNA polymerase activity|upregulation of deoxyribonucleic acid duplicase activity|positive regulation of lambda DNA polymerase activity|up-regulation of beta DNA polymerase activity|up regulation of alpha DNA polymerase activity|upregulation of epsilon DNA polymerase activity|activation of kappa DNA polymerase activity|upregulation of deoxyribonucleic polymerase I|up regulation of DNA-directed DNA polymerase activity|up regulation of gamma DNA-directed DNA polymerase activity|up regulation of lambda DNA polymerase activity|up regulation of eta DNA polymerase activity|up regulation of DNA replicase activity|up regulation of Taq DNA polymerase|up-regulation of DNA polymerase V activity|activation of zeta DNA polymerase activity|positive regulation of epsilon DNA polymerase activity|upregulation of mu DNA polymerase activity|upregulation of DNA polymerase I|up regulation of epsilon DNA polymerase activity|activation of sequenase|activation of alpha DNA polymerase activity|positive regulation of beta DNA polymerase activity|up-regulation of theta DNA polymerase activity|positive regulation of DNA polymerase III|activation of Taq DNA polymerase|up-regulation of deoxyribonucleic polymerase I|up regulation of deoxyribonucleic duplicase activity|up regulation of delta DNA polymerase activity|positive regulation of deoxyribonucleic polymerase I|upregulation of DNA replicase activity|activation of epsilon DNA polymerase activity|up-regulation of duplicase|upregulation of eta DNA polymerase activity|positive regulation of alpha DNA polymerase activity|up regulation of DNA-dependent DNA polymerase activity|positive regulation of eta DNA polymerase activity|activation of deoxyribonucleic duplicase activity|up regulation of DNA nucleotidyltransferase (DNA-directed) activity|positive regulation of DNA polymerase II|activation of deoxyribonucleic acid duplicase activity|up regulation of DNA polymerase alpha|up-regulation of mu DNA polymerase activity|up-regulation of deoxyribonucleic acid duplicase activity|positive regulation of DNA polymerase V activity|activation of DNA nucleotidyltransferase (DNA-directed) activity|upregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|up-regulation of sequenase|positive regulation of DNA polymerase I|up regulation of Taq Pol I|positive regulation of DNA polymerase alpha|upregulation of DNA polymerase II|up-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|activation of theta DNA polymerase activity|positive regulation of Klenow fragment|upregulation of beta DNA polymerase activity|up-regulation of Klenow fragment|up-regulation of nu DNA polymerase activity|activation of lambda DNA polymerase activity|upregulation of Taq Pol I|up regulation of DNA polymerase gamma|up-regulation of lambda DNA polymerase activity|up regulation of sequenase|up regulation of Tca DNA polymerase|activation of DNA polymerase I|upregulation of iota DNA polymerase activity|up regulation of nu DNA polymerase activity|positive regulation of DNA replicase activity|up-regulation of DNA polymerase I|activation of mu DNA polymerase activity|up regulation of duplicase|up-regulation of DNA nucleotidyltransferase (DNA-directed) activity|up-regulation of DNA duplicase activity|up-regulation of DNA polymerase III|up regulation of sigma DNA polymerase activity|activation of DNA replicase activity|up-regulation of iota DNA polymerase activity|positive regulation of kappa DNA polymerase activity|positive regulation of deoxyribonucleic acid duplicase activity|up-regulation of Taq Pol I|activation of DNA-dependent DNA polymerase activity|positive regulation of DNA-dependent DNA polymerase activity|upregulation of DNA duplicase activity|upregulation of nu DNA polymerase activity|positive regulation of sigma DNA polymerase activity|activation of Tca DNA polymerase						tb	2012-04-03T11:07:27Z						biological_process											owl:Class	
GO:0015876	biolink:NamedThing	acetyl-CoA transport	The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.	got7fsn_ti														biological_process											owl:Class	
GO:0042931	biolink:NamedThing	enterobactin transmembrane transporter activity	Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.	got7fsn_ti	enterobactin transporter activity|enterochelin transporter activity													molecular_function											owl:Class	
GO:0042669	biolink:NamedThing	regulation of inner ear auditory receptor cell fate specification	Any process that mediates the specification of a cell into an auditory hair cell.	got7fsn_ti	regulation of inner ear auditory receptor cell fate specification|regulation of auditory hair cell fate specification													biological_process											owl:Class	
GO:1904302	biolink:NamedThing	negative regulation of maternal process involved in parturition	Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition.	got7fsn_ti	down regulation of maternal process involved in parturition|inhibition of maternal process involved in parturition|downregulation of maternal process involved in parturition|down-regulation of maternal process involved in parturition						sl	2015-06-09T23:01:38Z						biological_process											owl:Class	
GO:0015797	biolink:NamedThing	mannitol transport	The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.	got7fsn_ti														biological_process											owl:Class	
GO:0019991	biolink:NamedThing	septate junction assembly	The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.	got7fsn_ti														biological_process											owl:Class	
GO:0060667	biolink:NamedThing	branch elongation involved in salivary gland morphogenesis	The differential growth of the salivary branches along their axis, resulting in the growth of a branch.	got7fsn_ti							dph	2009-06-01T09:42:13Z						biological_process											owl:Class	
GO:0015204	biolink:NamedThing	urea transmembrane transporter activity	Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.	got7fsn_ti	urea transporter activity										GO:0015287	RHEA:32799|Reactome:R-HSA-444126		molecular_function											owl:Class	
GO:0061097	biolink:NamedThing	regulation of protein tyrosine kinase activity	Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.	got7fsn_ti							dph	2010-04-26T02:34:53Z						biological_process											owl:Class	
GO:0032820	biolink:NamedThing	regulation of natural killer cell proliferation involved in immune response	Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response.	got7fsn_ti	regulation of natural killer cell proliferation during immune response|regulation of NK cell proliferation during immune response													biological_process											owl:Class	
GO:0015685	biolink:NamedThing	ferric-enterobactin import into cell	A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors.	got7fsn_ti	ferric-enterobactin transport													biological_process											owl:Class	
SO:0000276	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014904	biolink:NamedThing	myotube cell development	The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	got7fsn_ti														biological_process											owl:Class	
GO:0014011	biolink:NamedThing	Schwann cell proliferation involved in axon regeneration	The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:1901252	biolink:NamedThing	regulation of intracellular transport of viral material	Any process that modulates the frequency, rate or extent of egress of virus within host cell.	got7fsn_ti	regulation of movement of virus within host cell|regulation of egress of virus within host cell|regulation of viral egress						ss	2012-08-09T05:45:25Z						biological_process											owl:Class	
GO:0120143	biolink:NamedThing	negative regulation of ecdysone receptor-mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.	got7fsn_ti							krc	2018-03-22T17:28:29Z						biological_process											owl:Class	
GO:0150022	biolink:NamedThing	apical dendrite development	The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure.	got7fsn_ti							bc	2017-12-22T11:52:40Z						biological_process											owl:Class	
GO:0034202	biolink:NamedThing	glycolipid floppase activity	Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	glycolipid-translocating activity|glycolipid floppase activity (cytosolic to exoplasmic leaftlet)|ATPase-coupled intramembrane glycolipid transporter activity|ATP-dependent intramembrane glycolipid transporter activity											Reactome:R-HSA-446212|Reactome:R-HSA-4570573		molecular_function											owl:Class	
GO:0034203	biolink:NamedThing	glycolipid translocation	The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	got7fsn_ti														biological_process											owl:Class	
GO:1904379	biolink:NamedThing	protein localization to cytosolic proteasome complex involved in ERAD pathway	Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation.	got7fsn_ti	protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation to cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization in cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization to cytosolic proteasome complex involved in ER-associated degradation pathway|protein localization in cytosolic proteasome complex involved in ERAD pathway|protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation to cytosolic proteasome complex involved in ERAD pathway|protein localisation in cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation in cytosolic proteasome complex involved in ERAD pathway|protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway						bf	2015-06-23T09:30:07Z						biological_process											owl:Class	
GO:1902813	biolink:NamedThing	negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.	got7fsn_ti	down-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|downregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|downregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|inhibition of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|down-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|downregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination						mr	2014-03-26T21:18:50Z						biological_process											owl:Class	
GO:0032079	biolink:NamedThing	positive regulation of endodeoxyribonuclease activity	Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	got7fsn_ti	up-regulation of endodeoxyribonuclease activity|activation of endodeoxyribonuclease activity|upregulation of endodeoxyribonuclease activity|stimulation of endodeoxyribonuclease activity|up regulation of endodeoxyribonuclease activity|endodeoxyribonuclease activator													biological_process											owl:Class	
GO:0098522	biolink:NamedThing	neuromuscular junction of skeletal muscle fiber	A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber.	got7fsn_ti					In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are  cholinergic and excitatory.  Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.		dos	2013-10-14T12:04:32Z						cellular_component											owl:Class	
GO:1905936	biolink:NamedThing	regulation of germ cell proliferation	Any process that modulates the frequency, rate or extent of germ cell proliferation.	got7fsn_ti							hbye	2017-02-09T14:51:31Z						biological_process											owl:Class	
GO:0046623	biolink:NamedThing	sphingolipid floppase activity	Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	sphingolipid-translocating ATPase activity|sphingolipid flippase activity|sphingolipid floppase activity (cytosolic to exoplasmic leaftlet)													molecular_function											owl:Class	
GO:0099039	biolink:NamedThing	sphingolipid translocation	The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.	got7fsn_ti														biological_process											owl:Class	
CHEBI:15355	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904836	biolink:NamedThing	facioacoustic ganglion morphogenesis	The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized.	got7fsn_ti	facio-acoustic ganglion complex VII-VIII morphogenesis|facio-acoustic ganglion complex morphogenesis|facio-acoustic ganglion morphogenesis|acousticofacial ganglion morphogenesis|facio-acoustic VII-VIII ganglion complex morphogenesis|acoustico-facial VII-VIII ganglion complex morphogenesis						bf	2015-12-01T17:02:06Z						biological_process											owl:Class	
GO:1903375	biolink:NamedThing	facioacoustic ganglion development	The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure.	got7fsn_ti	facio-acoustic VII-VIII ganglion complex development|facio-acoustic ganglion development|acoustico-facial VII-VIII ganglion complex development|facio-acoustic ganglion complex VII-VIII development|acousticofacial ganglion development						bf	2014-08-26T12:40:36Z						biological_process											owl:Class	
GO:1905623	biolink:NamedThing	positive regulation of leaf development	Any process that activates or increases the frequency, rate or extent of leaf development.	got7fsn_ti	up-regulation of leaf development|up regulation of leaf development|activation of leaf development|upregulation of leaf development						pga	2016-10-28T15:30:04Z						biological_process											owl:Class	
GO:0009359	biolink:NamedThing	type II site-specific deoxyribonuclease complex	A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.	got7fsn_ti	type II restriction enzyme complex													cellular_component											owl:Class	
GO:2000748	biolink:NamedThing	positive regulation of defecation rhythm	Any process that activates or increases the frequency, rate or extent of defecation rhythm.	got7fsn_ti	positive regulation of defecation behavior|positive regulation of defecation cycle|positive regulation of DMP|positive regulation of defecation motor program						bf	2011-06-15T03:23:13Z						biological_process											owl:Class	
GO:0010950	biolink:NamedThing	positive regulation of endopeptidase activity	Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.	got7fsn_ti							tb	2009-04-27T11:45:39Z						biological_process											owl:Class	
GO:0140194	biolink:NamedThing	negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.	got7fsn_ti							pg	2018-02-15T19:13:02Z						biological_process											owl:Class	
GO:0002789	biolink:NamedThing	negative regulation of antifungal peptide production	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.	got7fsn_ti	downregulation of antifungal peptide production|down-regulation of antifungal peptide production|inhibition of antifungal peptide production|down regulation of antifungal peptide production													biological_process											owl:Class	
GO:2000557	biolink:NamedThing	regulation of immunoglobulin production in mucosal tissue	Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue.	got7fsn_ti	regulation of antibody production in mucosal tissue						ebc	2011-04-03T07:52:09Z						biological_process											owl:Class	
GO:2000808	biolink:NamedThing	negative regulation of synaptic vesicle clustering	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering.	got7fsn_ti							pr	2011-07-06T09:50:34Z						biological_process											owl:Class	
GO:1905781	biolink:NamedThing	negative regulation of phosphatidylserine exposure on apoptotic cell surface	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.	got7fsn_ti	inhibition of phosphatidylserine exposure on apoptotic cell surface|down-regulation of phosphatidylserine exposure on apoptotic cell surface|down-regulation of externalization of phosphatidylserine|down regulation of externalization of phosphatidylserine|down regulation of phosphatidylserine exposure on apoptotic cell surface|inhibition of externalization of phosphatidylserine|downregulation of externalization of phosphatidylserine|negative regulation of externalization of phosphatidylserine|downregulation of phosphatidylserine exposure on apoptotic cell surface						kmv	2017-01-04T15:19:14Z						biological_process											owl:Class	
GO:2000650	biolink:NamedThing	negative regulation of sodium ion transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.	got7fsn_ti	negative regulation of sodium transporter activity						yaf	2011-04-28T08:42:57Z						biological_process											owl:Class	
GO:0043879	biolink:NamedThing	glycolate transmembrane transporter activity	Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA).	got7fsn_ti	glycolate permease|glcA|glycolic acid transmembrane transporter activity|hydroxyacetic acid transmembrane transporter activity											RHEA:29447		molecular_function											owl:Class	
GO:0097339	biolink:NamedThing	glycolate transmembrane transport	The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid).	got7fsn_ti	glycolate membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		pr	2012-06-12T05:12:35Z						biological_process											owl:Class	
GO:0016507	biolink:NamedThing	mitochondrial fatty acid beta-oxidation multienzyme complex	A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix.	got7fsn_ti	trifunctional enzyme|fatty acid beta-oxidation multienzyme complex													cellular_component											owl:Class	
PATO:0002487	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031304	biolink:NamedThing	intrinsic component of mitochondrial inner membrane	The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to mitochondrial inner membrane													cellular_component											owl:Class	
GO:1901399	biolink:NamedThing	negative regulation of transforming growth factor beta3 activation	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation.	got7fsn_ti	down-regulation of TGF-beta 3 activation|negative regulation of TGFbeta 3 activation|negative regulation of TGF-beta 3 activation|down regulation of TGFB3 activation|down regulation of TGFbeta 3 activation|down-regulation of TGFB3 activation|down-regulation of TGFbeta 3 activation|down regulation of transforming growth factor beta3 activation|inhibition of TGFB3 activation|inhibition of transforming growth factor beta3 activation|down-regulation of transforming growth factor beta3 activation|negative regulation of TGFB3 activation|inhibition of TGFbeta 3 activation|downregulation of TGFB3 activation|inhibition of TGF-beta 3 activation|downregulation of TGFbeta 3 activation|downregulation of TGF-beta 3 activation|downregulation of transforming growth factor beta3 activation|down regulation of TGF-beta 3 activation						bf	2012-10-01T10:50:32Z						biological_process											owl:Class	
UBERON:0000059	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042929	biolink:NamedThing	ferrichrome transmembrane transporter activity	Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.	got7fsn_ti	ferrichrome transporter activity													molecular_function											owl:Class	
GO:0042928	biolink:NamedThing	ferrichrome import into cell	A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.	got7fsn_ti	ferrichrome transport													biological_process											owl:Class	
GO:0070418	biolink:NamedThing	DNA-dependent protein kinase complex	A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku.	got7fsn_ti	DNA-dependent protein kinase, DNA-end-binding complex|DNA-PK-Ku antigen complex|DNA-PK complex													cellular_component											owl:Class	
GO:0086080	biolink:NamedThing	protein binding involved in heterotypic cell-cell adhesion	Binding to a protein or protein complex contributing to the adhesion of two different types of cells.	got7fsn_ti							dph	2011-11-22T10:53:52Z						molecular_function											owl:Class	
GO:1904029	biolink:NamedThing	regulation of cyclin-dependent protein kinase activity	Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity.	got7fsn_ti							als	2015-03-13T15:43:38Z						biological_process											owl:Class	
GO:0032413	biolink:NamedThing	negative regulation of ion transmembrane transporter activity	Any process that stops or reduces the activity of an ion transporter.	got7fsn_ti	downregulation of ion transporter activity|down-regulation of ion transporter activity|down regulation of ion transporter activity|negative regulation of ion transporter activity|inhibition of ion transporter activity													biological_process											owl:Class	
GO:0000923	biolink:NamedThing	equatorial microtubule organizing center	A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis.	got7fsn_ti	EMTOC|equatorial microtubule organising centre													cellular_component											owl:Class	
GO:0032400	biolink:NamedThing	melanosome localization	Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	melanosome localisation													biological_process											owl:Class	
GO:0045624	biolink:NamedThing	positive regulation of T-helper cell differentiation	Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.	got7fsn_ti	up regulation of T-helper cell differentiation|stimulation of T-helper cell differentiation|upregulation of T-helper cell differentiation|activation of T-helper cell differentiation|up-regulation of T-helper cell differentiation|positive regulation of T-helper cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:2000175	biolink:NamedThing	negative regulation of pro-T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.	got7fsn_ti	negative regulation of pro-T lymphocyte differentiation						mah	2010-10-11T10:24:33Z						biological_process											owl:Class	
GO:0015133	biolink:NamedThing	uronic acid transmembrane transporter activity	Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.	got7fsn_ti														molecular_function											owl:Class	
GO:0015735	biolink:NamedThing	uronic acid transmembrane transport	The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	uronic acid transport													biological_process											owl:Class	
GO:0071378	biolink:NamedThing	cellular response to growth hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.	got7fsn_ti							mah	2009-12-11T03:25:17Z						biological_process											owl:Class	
GO:2000329	biolink:NamedThing	negative regulation of T-helper 17 cell lineage commitment	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment.	got7fsn_ti	negative regulation of Th17 fate commitment|negative regulation of T-helper 17 cell fate commitment|negative regulation of Th17 cell lineage commitment						mah	2011-01-19T09:31:53Z						biological_process											owl:Class	
GO:0070953	biolink:NamedThing	regulation of neutrophil mediated killing of fungus	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.	got7fsn_ti							mah	2009-10-01T02:14:36Z						biological_process											owl:Class	
GO:0015663	biolink:NamedThing	nicotinamide mononucleotide transmembrane transporter activity	Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.	got7fsn_ti	nicotinamide mononucleotide permease activity|nicotinamide ribonucleotide transmembrane transporter activity										GO:0015664			molecular_function											owl:Class	
GO:0035353	biolink:NamedThing	nicotinamide mononucleotide transmembrane transport	The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.	got7fsn_ti	nicotinamide mononucleotide membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:46:55Z						biological_process											owl:Class	
GO:0042556	biolink:NamedThing	eukaryotic elongation factor-2 kinase regulator activity	Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase.	got7fsn_ti	eEF-2 kinase regulator													molecular_function											owl:Class	
GO:0030505	biolink:NamedThing	inorganic diphosphate transport	The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	inorganic pyrophosphate transport													biological_process											owl:Class	
GO:0010572	biolink:NamedThing	positive regulation of platelet activation	Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.	got7fsn_ti														biological_process											owl:Class	
NCBITaxon:Union_0000022	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042880	biolink:NamedThing	D-glucuronate transmembrane transporter activity	Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0042874	biolink:NamedThing	D-glucuronate transmembrane transport	The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	D-glucuronate transport													biological_process											owl:Class	
GO:1900106	biolink:NamedThing	positive regulation of hyaluranon cable assembly	Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly.	got7fsn_ti	positive regulation of HA cable assembly|upregulation of hyaluranon cable assembly|up regulation of hyaluranon cable assembly|activation of hyaluranon cable assembly|up-regulation of hyaluranon cable assembly|up-regulation of HA cable assembly|upregulation of HA cable assembly|activation of HA cable assembly|up regulation of HA cable assembly						yaf	2012-02-16T01:00:54Z						biological_process											owl:Class	
GO:1902846	biolink:NamedThing	positive regulation of mitotic spindle elongation	Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation.	got7fsn_ti	up-regulation of spindle elongation during mitosis|activation of mitotic spindle elongation|up regulation of mitotic spindle elongation|upregulation of mitotic spindle elongation|up regulation of spindle elongation during mitosis|activation of spindle elongation during mitosis|upregulation of spindle elongation during mitosis|positive regulation of spindle elongation during mitosis|up-regulation of mitotic spindle elongation						vw	2014-04-02T08:43:34Z						biological_process											owl:Class	
GO:0061089	biolink:NamedThing	negative regulation of sequestering of zinc ion	Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.	got7fsn_ti							dph	2010-04-26T01:38:53Z						biological_process											owl:Class	
GO:0045623	biolink:NamedThing	negative regulation of T-helper cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation.	got7fsn_ti	negative regulation of T-helper cell development|downregulation of T-helper cell differentiation|inhibition of T-helper cell differentiation|down-regulation of T-helper cell differentiation|down regulation of T-helper cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0045313	biolink:NamedThing	rhabdomere membrane biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0071071	biolink:NamedThing	regulation of phospholipid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.	got7fsn_ti	regulation of phospholipid anabolism|regulation of phospholipid biosynthesis|regulation of phospholipid synthesis|regulation of phospholipid formation						mah	2009-11-04T03:05:11Z						biological_process											owl:Class	
GO:0009843	biolink:NamedThing	cyanelle thylakoid	A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria.	got7fsn_ti														cellular_component											owl:Class	
GO:0062199	biolink:NamedThing	chromosome, centromeric inner repeat region	The portion of the centromeric region of a chromosome that contains the inner inverted repeat region of a modular centromere and part of the central core surrounding a non-conserved central region. This region is adjacent to the central core, on each chromosome arm.	got7fsn_ti	chromosome, centric outer repeat region						dph	2019-12-11T20:38:14Z						cellular_component											owl:Class	
GO:0043951	biolink:NamedThing	negative regulation of cAMP-mediated signaling	Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.	got7fsn_ti	negative regulation of cAMP-mediated signalling													biological_process											owl:Class	
GO:0009328	biolink:NamedThing	phenylalanine-tRNA ligase complex	An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).	got7fsn_ti														cellular_component											owl:Class	
GO:2000556	biolink:NamedThing	positive regulation of T-helper 1 cell cytokine production	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production.	got7fsn_ti	positive regulation of Th1 cell cytokine production						ebc	2011-04-03T07:35:56Z						biological_process											owl:Class	
GO:0015185	biolink:NamedThing	gamma-aminobutyric acid transmembrane transporter activity	Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).	got7fsn_ti	4-aminobutyrate transporter activity|betaine/GABA:sodium symporter activity|GABA transporter activity|4-aminobutanoate transporter activity													molecular_function											owl:Class	
GO:0015812	biolink:NamedThing	gamma-aminobutyric acid transport	The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	4-aminobutanoate transport|GABA transport|4-aminobutyrate transport				See also the biological process term 'neurotransmitter transport ; GO:0006836'.									biological_process											owl:Class	
GO:1902234	biolink:NamedThing	positive regulation of positive thymic T cell selection	Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection.	got7fsn_ti	activation of positive thymic T-cell selection|upregulation of positive thymic T-lymphocyte selection|up regulation of positive thymic T-cell selection|positive regulation of positive thymic T-cell selection|activation of positive thymic T cell selection|upregulation of positive thymic T-cell selection|positive regulation of positive thymic T-lymphocyte selection|up-regulation of positive thymic T-lymphocyte selection|activation of positive thymic T lymphocyte selection|up-regulation of positive thymic T cell selection|up regulation of positive thymic T lymphocyte selection|positive regulation of positive thymic T lymphocyte selection|up regulation of positive thymic T cell selection|up-regulation of positive thymic T-cell selection|up regulation of positive thymic T-lymphocyte selection|activation of positive thymic T-lymphocyte selection|up-regulation of positive thymic T lymphocyte selection|upregulation of positive thymic T cell selection|upregulation of positive thymic T lymphocyte selection						lb	2013-06-14T11:19:20Z						biological_process											owl:Class	
GO:1902748	biolink:NamedThing	positive regulation of lens fiber cell differentiation	Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation.	got7fsn_ti	activation of lens fiber cell differentiation|up-regulation of lens fibre cell differentiation|upregulation of lens fibre cell differentiation|up-regulation of lens fiber cell differentiation|up regulation of lens fiber cell differentiation|positive regulation of lens fibre cell differentiation|upregulation of lens fiber cell differentiation|activation of lens fibre cell differentiation|up regulation of lens fibre cell differentiation						mr	2014-03-03T23:20:12Z						biological_process											owl:Class	
GO:0042926	biolink:NamedThing	3-hydroxyphenylpropionic acid transmembrane transporter activity	Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other.	got7fsn_ti	3-(3-hydroxyphenyl)propionic acid transporter activity|3-hydroxyphenylpropionic acid transporter activity|m-hydroxyphenylpropionic acid transporter activity													molecular_function											owl:Class	
GO:0042920	biolink:NamedThing	3-hydroxyphenylpropionic acid transmembrane transport	The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	3-(3-hydroxyphenyl)propionic acid transport|3-hydroxyphenylpropionic acid transport|m-hydroxyphenylpropionic acid transport													biological_process											owl:Class	
GO:1905598	biolink:NamedThing	negative regulation of low-density lipoprotein receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity.	got7fsn_ti	inhibition of LDL receptor|negative regulation of LDLR activity|down regulation of LDLR activity|downregulation of LDLR activity|down-regulation of low-density lipoprotein receptor activity|inhibition of low-density lipoprotein receptor activity|negative regulation of LDL receptor|downregulation of low-density lipoprotein receptor activity|down regulation of LDL receptor|downregulation of LDL receptor|down regulation of low-density lipoprotein receptor activity|inhibition of LDLR activity|down-regulation of LDLR activity|down-regulation of LDL receptor						nc	2016-10-26T11:53:34Z						biological_process											owl:Class	
GO:0043380	biolink:NamedThing	regulation of memory T cell differentiation	Any process that modulates the frequency, rate, or extent of memory T cell differentiation.	got7fsn_ti	regulation of memory T-lymphocyte differentiation|regulation of memory T lymphocyte differentiation|regulation of memory T-cell differentiation|regulation of memory T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1905618	biolink:NamedThing	positive regulation of miRNA mediated inhibition of translation	Any process that activates or increases the frequency, rate or extent of miRNA mediated inhibition of translation.	got7fsn_ti	activation of downregulation of translation involved in gene silencing by miRNA|up-regulation of down-regulation of translation involved in gene silencing by miRNA|up regulation of negative regulation of translation involved in gene silencing by microRNA|up regulation of miRNA mediated inhibition of translation|upregulation of downregulation of translation involved in gene silencing by miRNA|positive regulation of down-regulation of translation involved in gene silencing by miRNA|activation of down regulation of translation involved in gene silencing by miRNA|activation of down-regulation of translation involved in gene silencing by miRNA|activation of miRNA-mediated gene silencing, negative regulation of translation|upregulation of miRNA-mediated gene silencing, negative regulation of translation|upregulation of down-regulation of translation involved in gene silencing by miRNA|up regulation of downregulation of translation involved in gene silencing by miRNA|up regulation of gene silencing by miRNA, negative regulation of translation|positive regulation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of miRNA mediated inhibition of translation|positive regulation of gene silencing by miRNA, negative regulation of translation|positive regulation of downregulation of translation involved in gene silencing by miRNA|up regulation of miRNA-mediated gene silencing, negative regulation of translation|positive regulation of inhibition of translation involved in gene silencing by miRNA|up-regulation of miRNA-mediated gene silencing, negative regulation of translation|upregulation of down regulation of translation involved in gene silencing by miRNA|up-regulation of inhibition of translation involved in gene silencing by miRNA|positive regulation of down regulation of translation involved in gene silencing by miRNA|up regulation of down-regulation of translation involved in gene silencing by miRNA|activation of gene silencing by miRNA, negative regulation of translation|upregulation of miRNA mediated inhibition of translation|upregulation of gene silencing by miRNA, negative regulation of translation|upregulation of inhibition of translation involved in gene silencing by miRNA|up-regulation of downregulation of translation involved in gene silencing by miRNA|up regulation of down regulation of translation involved in gene silencing by miRNA|upregulation of negative regulation of translation involved in gene silencing by microRNA|activation of inhibition of translation involved in gene silencing by miRNA|activation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of gene silencing by miRNA, negative regulation of translation|up-regulation of down regulation of translation involved in gene silencing by miRNA|up regulation of inhibition of translation involved in gene silencing by miRNA|activation of miRNA mediated inhibition of translation|positive regulation of miRNA-mediated gene silencing, negative regulation of translation|up-regulation of negative regulation of translation involved in gene silencing by microRNA						bc	2016-10-28T11:48:04Z						biological_process											owl:Class	
GO:0045637	biolink:NamedThing	regulation of myeloid cell differentiation	Any process that modulates the frequency, rate or extent of myeloid cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0120137	biolink:NamedThing	positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.	got7fsn_ti							krc	2018-03-21T21:59:55Z						biological_process											owl:Class	
GO:0051459	biolink:NamedThing	regulation of corticotropin secretion	Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.	got7fsn_ti	regulation of adrenotropin secretion|regulation of adrenotropin hormone secretion|regulation of adrenocorticotropic hormone secretion|regulation of ACTH secretion|regulation of adrenocorticotropin secretion|regulation of corticotropic hormone secretion													biological_process											owl:Class	
GO:1903468	biolink:NamedThing	positive regulation of DNA replication initiation	Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.	got7fsn_ti	up regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|up regulation of DNA replication initiation involved in mitotic DNA replication|up-regulation of DNA replication initiation involved in mitotic DNA replication|up-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|activation of DNA replication initiation involved in mitotic cell cycle DNA replication|positive regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|upregulation of DNA replication initiation involved in mitotic cell cycle DNA replication|upregulation of DNA replication initiation involved in mitotic DNA replication|activation of DNA replication initiation involved in mitotic DNA replication						vw	2014-09-23T13:39:06Z						biological_process											owl:Class	
CL:0000218	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071073	biolink:NamedThing	positive regulation of phospholipid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.	got7fsn_ti	positive regulation of phospholipid synthesis|upregulation of phospholipid biosynthetic process|up regulation of phospholipid biosynthetic process|stimulation of phospholipid biosynthetic process|positive regulation of phospholipid biosynthesis|positive regulation of phospholipid formation|up-regulation of phospholipid biosynthetic process|activation of phospholipid biosynthetic process|positive regulation of phospholipid anabolism						mah	2009-11-04T03:18:51Z						biological_process											owl:Class	
GO:0009157	biolink:NamedThing	deoxyribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	deoxyribonucleoside monophosphate formation|deoxyribonucleoside monophosphate synthesis|deoxyribonucleoside monophosphate biosynthesis|deoxyribonucleoside monophosphate anabolism													biological_process											owl:Class	
GO:0015127	biolink:NamedThing	bilirubin transmembrane transporter activity	Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.	got7fsn_ti												Reactome:R-HSA-9661417|Reactome:R-HSA-5679031|Reactome:R-HSA-5679041		molecular_function											owl:Class	
GO:0015723	biolink:NamedThing	bilirubin transport	The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1902943	biolink:NamedThing	positive regulation of voltage-gated chloride channel activity	Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity.	got7fsn_ti	activation of voltage-dependent chloride channel activity|activation of voltage-gated chloride channel activity|upregulation of voltage-gated chloride channel activity|up-regulation of voltage-gated chloride channel activity|up-regulation of voltage-dependent chloride channel activity|upregulation of voltage gated chloride channel activity|activation of voltage gated chloride channel activity|up regulation of voltage-dependent chloride channel activity|up-regulation of voltage gated chloride channel activity|positive regulation of voltage-dependent chloride channel activity|positive regulation of voltage gated chloride channel activity|up regulation of voltage-gated chloride channel activity|upregulation of voltage-dependent chloride channel activity|up regulation of voltage gated chloride channel activity						als	2014-04-28T08:55:43Z						biological_process											owl:Class	
GO:1902951	biolink:NamedThing	negative regulation of dendritic spine maintenance	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.	got7fsn_ti	down regulation of dendritic spine maintenance|down-regulation of dendritic spine maintenance|inhibition of dendritic spine maintenance|downregulation of dendritic spine maintenance						sjp	2014-05-02T08:48:53Z						biological_process											owl:Class	
GO:1904457	biolink:NamedThing	positive regulation of neuronal action potential	Any process that activates or increases the frequency, rate or extent of neuronal action potential.	got7fsn_ti	activation of generation of action potential|up regulation of neuronal action potential|up-regulation of generation of action potential|upregulation of generation of action potential|positive regulation of generation of action potential|up-regulation of neuronal action potential|activation of neuronal action potential|up regulation of generation of action potential|upregulation of neuronal action potential						sl	2015-07-09T18:02:46Z						biological_process											owl:Class	
GO:0031149	biolink:NamedThing	sorocarp stalk cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	stalk cell differentiation													biological_process											owl:Class	
GO:1903954	biolink:NamedThing	positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.	got7fsn_ti	upregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|positive regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|up-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|upregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|up-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|up regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|activation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|up regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|activation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization						nc	2015-02-24T10:32:24Z						biological_process											owl:Class	
GO:1903979	biolink:NamedThing	negative regulation of microglial cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation.	got7fsn_ti	down regulation of microglial cell activation|down-regulation of microglial cell activation|downregulation of microglial cell activation|inhibition of microglial cell activation						nc	2015-03-02T15:17:39Z						biological_process											owl:Class	
GO:0048633	biolink:NamedThing	positive regulation of skeletal muscle tissue growth	Any process that activates, maintains or increases the rate of skeletal muscle growth.	got7fsn_ti	upregulation of skeletal muscle growth|stimulation of skeletal muscle growth|activation of skeletal muscle growth|up-regulation of skeletal muscle growth|up regulation of skeletal muscle growth													biological_process											owl:Class	
CHEBI:57856	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070962	biolink:NamedThing	positive regulation of neutrophil mediated killing of bacterium	Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.	got7fsn_ti	up regulation of neutrophil mediated killing of bacterium|activation of neutrophil mediated killing of bacterium|stimulation of neutrophil mediated killing of bacterium|up-regulation of neutrophil mediated killing of bacterium|upregulation of neutrophil mediated killing of bacterium						mah	2009-10-01T02:28:49Z						biological_process											owl:Class	
GO:0003253	biolink:NamedThing	cardiac neural crest cell migration involved in outflow tract morphogenesis	The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.	got7fsn_ti							dph	2009-10-13T02:14:16Z						biological_process											owl:Class	
GO:0061309	biolink:NamedThing	cardiac neural crest cell development involved in outflow tract morphogenesis	The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.	got7fsn_ti							dph	2010-09-23T09:08:37Z						biological_process											owl:Class	
GO:0060015	biolink:NamedThing	granulosa cell fate commitment	The cell fate commitment of precursor cells that will become granulosa cells.	got7fsn_ti														biological_process											owl:Class	
GO:1904970	biolink:NamedThing	brush border assembly	The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border.	got7fsn_ti	brush border formation						tb	2016-02-17T00:58:30Z						biological_process											owl:Class	
GO:0043382	biolink:NamedThing	positive regulation of memory T cell differentiation	Any process that activates or increases the frequency, rate or extent of memory T cell differentiation.	got7fsn_ti	upregulation of memory T cell differentiation|stimulation of memory T cell differentiation|up regulation of memory T cell differentiation|positive regulation of memory T-lymphocyte differentiation|up-regulation of memory T cell differentiation|positive regulation of memory T-cell differentiation|activation of memory T cell differentiation|positive regulation of memory T lymphocyte differentiation|positive regulation of memory T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
OBO:OPL_0000076	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006780	biolink:NamedThing	uroporphyrinogen III biosynthetic process	The chemical reactions and pathways resulting in the formation of uroporphyrinogen III.	got7fsn_ti	uroporphyrinogen III formation|uroporphyrinogen III anabolism|uroporphyrinogen III biosynthesis|uroporphyrinogen III synthesis													biological_process											owl:Class	
GO:0070949	biolink:NamedThing	regulation of neutrophil mediated killing of symbiont cell	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.	got7fsn_ti							mah	2009-10-01T02:14:36Z						biological_process											owl:Class	
GO:0150068	biolink:NamedThing	positive regulation of tubulin deacetylase activity	Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity.	got7fsn_ti							bc	2018-07-24T10:35:51Z						biological_process											owl:Class	
GO:0019550	biolink:NamedThing	glutamate catabolic process to aspartate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate.	got7fsn_ti	glutamate degradation to aspartate|glutamate breakdown to aspartate											MetaCyc:GLUTDEG-PWY		biological_process											owl:Class	
GO:0060334	biolink:NamedThing	regulation of interferon-gamma-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.	got7fsn_ti	regulation of type II interferon-mediated signaling pathway|regulation of gamma-interferon-mediated signaling pathway|regulation of immune interferon signaling pathway|regulation of interferon-gamma-mediated signalling pathway|regulation of type II IFN-mediated signaling pathway													biological_process											owl:Class	
GO:0060728	biolink:NamedThing	negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.	got7fsn_ti	negative regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway|negative regulation of Neu/ErbB-2 receptor activity						dph	2009-06-12T01:32:38Z						biological_process											owl:Class	
GO:0003134	biolink:NamedThing	endodermal-mesodermal cell signaling involved in heart induction	Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction.	got7fsn_ti	endodermal-mesodermal cell signalling involved in heart induction						tb	2009-09-22T03:11:17Z						biological_process											owl:Class	
GO:0015113	biolink:NamedThing	nitrite transmembrane transporter activity	Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other.	got7fsn_ti	nitrite/nitrate porter activity													molecular_function											owl:Class	
GO:0015707	biolink:NamedThing	nitrite transport	The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0060278	biolink:NamedThing	regulation of ovulation	Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.	got7fsn_ti														biological_process											owl:Class	
GO:2000239	biolink:NamedThing	negative regulation of tRNA export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus.	got7fsn_ti	negative regulation of tRNA export out of nucleus|negative regulation of tRNA-nucleus export|negative regulation of tRNA transport from nucleus to cytoplasm|negative regulation of tRNA export from cell nucleus						mah	2010-11-10T12:39:36Z						biological_process											owl:Class	
GO:0042648	biolink:NamedThing	chloroplast chromosome	A circular DNA molecule containing chloroplast encoded genes.	got7fsn_ti														cellular_component											owl:Class	
GO:0048092	biolink:NamedThing	negative regulation of male pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.	got7fsn_ti	down-regulation of male pigmentation|downregulation of male pigmentation|down regulation of male pigmentation|inhibition of male pigmentation													biological_process											owl:Class	
GO:0071305	biolink:NamedThing	cellular response to vitamin D	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.	got7fsn_ti	cellular response to cholecalciferol|cellular response to calciferol|cellular response to ergocalciferol						mah	2009-12-10T04:35:37Z						biological_process											owl:Class	
GO:0015779	biolink:NamedThing	glucuronoside transport	The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.	got7fsn_ti	glucuronide transport													biological_process											owl:Class	
GO:0032926	biolink:NamedThing	negative regulation of activin receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.	got7fsn_ti	down-regulation of activin receptor signaling pathway|down regulation of activin receptor signaling pathway|negative regulation of activin signaling pathway|negative regulation of activin signalling pathway|inhibition of activin receptor signaling pathway|downregulation of activin receptor signaling pathway|negative regulation of activin receptor signalling pathway													biological_process											owl:Class	
GO:0061295	biolink:NamedThing	regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.	got7fsn_ti	regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis|regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis						dph	2010-09-06T09:48:56Z						biological_process											owl:Class	
GO:0061900	biolink:NamedThing	glial cell activation	A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti							dph	2017-06-13T13:06:23Z						biological_process											owl:Class	
GO:0045622	biolink:NamedThing	regulation of T-helper cell differentiation	Any process that modulates the frequency, rate or extent of T-helper cell differentiation.	got7fsn_ti	regulation of T-helper cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0016120	biolink:NamedThing	carotene biosynthetic process	The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.	got7fsn_ti	carotene biosynthesis|carotene formation|carotene anabolism|carotene synthesis													biological_process											owl:Class	
GO:0033339	biolink:NamedThing	pectoral fin development	The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0150202	biolink:NamedThing	negative regulation of transport across blood-brain barrier	Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier.	got7fsn_ti							bc	2020-03-26T19:28:51Z						biological_process											owl:Class	
GO:1903711	biolink:NamedThing	spermidine transmembrane transport	The process in which spermidine is transported across a membrane.	got7fsn_ti							vw	2014-12-06T08:12:44Z						biological_process											owl:Class	
OBO:OPL_0000022	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0086090	biolink:NamedThing	voltage-gated potassium channel activity involved in SA node cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-gated potassium channel activity involved in sinus node cell action potential|voltage-gated potassium channel activity involved in SAN cell action potential|voltage-gated potassium channel activity involved in sinoatrial node cell action potential						dph	2011-11-22T01:38:08Z						molecular_function											owl:Class	
GO:0086052	biolink:NamedThing	membrane repolarization during SA node cell action potential	The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	got7fsn_ti	membrane repolarization involved in regulation of sinoatrial node cardiac muscle cell action potential|membrane repolarization involved in regulation of sinus node cardiac muscle cell action potential|membrane repolarization involved in regulation of SA node cardiac muscle cell action potential|membrane repolarization involved in regulation of SAN cardiac muscle cell action potential						dph	2011-11-16T11:54:12Z						biological_process											owl:Class	
GO:1905325	biolink:NamedThing	regulation of meiosis I spindle assembly checkpoint	Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint.	got7fsn_ti							mah	2016-07-20T12:48:40Z						biological_process											owl:Class	
GO:0015156	biolink:NamedThing	melibiose transmembrane transporter activity	Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants.	got7fsn_ti														molecular_function											owl:Class	
GO:0015769	biolink:NamedThing	melibiose transport	The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.	got7fsn_ti														biological_process											owl:Class	
GO:0098804	biolink:NamedThing	non-motile cilium membrane	The portion of the plasma membrane surrounding a non-motile cilium.	got7fsn_ti	nonmotile primary cilium membrane													cellular_component											owl:Class	
GO:1902678	biolink:NamedThing	right caudal basal body	Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage).	got7fsn_ti	microtubule basal body of right caudal cilium|cilium basal body of right caudal cilium|right caudal flagellum ciliary basal body|cilium basal body of right caudal flagellum|cilial basal body of right caudal flagellum|ciliary basal body of right caudal flagellum|cilial basal body of right caudal cilium|ciliary basal body of right caudal cilium|microtubule basal body of right caudal flagellum				Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T15:02:56Z						cellular_component											owl:Class	
GO:0015169	biolink:NamedThing	glycerol-3-phosphate transmembrane transporter activity	Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.	got7fsn_ti														molecular_function											owl:Class	
GO:0015794	biolink:NamedThing	glycerol-3-phosphate transmembrane transport	The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol.	got7fsn_ti	glycerol-3-phosphate transport													biological_process											owl:Class	
GO:0035231	biolink:NamedThing	cytoneme assembly	Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.	got7fsn_ti	cytoneme biogenesis													biological_process											owl:Class	
GO:0003399	biolink:NamedThing	cytoneme morphogenesis	The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.	got7fsn_ti							dph	2009-12-09T10:03:32Z						biological_process											owl:Class	
GO:1903466	biolink:NamedThing	regulation of mitotic DNA replication initiation	Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.	got7fsn_ti	regulation of DNA replication initiation involved in mitotic cell cycle DNA replication						vw	2014-09-23T13:38:49Z						biological_process											owl:Class	
GO:1904451	biolink:NamedThing	regulation of potassium:proton exchanging ATPase activity	Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.	got7fsn_ti	regulation of hydrogen:potassium exchanging ATPase activity|regulation of H,K-ATPase activity|regulation of H+-K+-ATPase activity|regulation of hydrogen/potassium-exchanging ATPase activity|regulation of H(+)/K(+)-exchanging ATPase activity|regulation of hydrogen:potassium-exchanging ATPase activity|regulation of gastric H+/K+ ATPase|regulation of H+/K+-exchanging ATPase activity|regulation of (K+ + H+)-ATPase activity|regulation of H(+)/K(+)-ATPase activity|regulation of ATP phosphohydrolase (H+/K+-exchanging)|regulation of H+/K+-ATPase activity|regulation of gastric H(+)/K(+) ATPase activity|regulation of proton pump activity						sl	2015-07-08T23:00:03Z						biological_process											owl:Class	
GO:0071923	biolink:NamedThing	negative regulation of cohesin loading	Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.	got7fsn_ti	negative regulation of cohesin localisation to chromatin|negative regulation of cohesin localization to chromatin|negative regulation of cohesin association with chromatin						mah	2010-09-28T11:17:50Z						biological_process											owl:Class	
GO:0009331	biolink:NamedThing	glycerol-3-phosphate dehydrogenase complex	An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.	got7fsn_ti														cellular_component											owl:Class	
GO:0071513	biolink:NamedThing	phosphopantothenoylcysteine decarboxylase complex	A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.	got7fsn_ti					See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.		mah	2010-01-05T05:23:13Z						cellular_component											owl:Class	
GO:1902072	biolink:NamedThing	negative regulation of hypoxia-inducible factor-1alpha signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.	got7fsn_ti	down regulation of HIF1alpha pathway|down regulation of hypoxia-inducible factor-1alpha signaling pathway|negative regulation of HIF1alpha pathway|down-regulation of HIF1alpha pathway|down regulation of hypoxia-inducible factor-1alpha signalling pathway|downregulation of hypoxia-inducible factor-1alpha signaling pathway|inhibition of hypoxia-inducible factor-1alpha signaling pathway|inhibition of hypoxia-inducible factor-1alpha signalling pathway|down-regulation of hypoxia-inducible factor-1alpha signalling pathway|down-regulation of hypoxia-inducible factor-1alpha signaling pathway|downregulation of HIF1alpha pathway|negative regulation of hypoxia-inducible factor-1alpha signalling pathway|inhibition of HIF1alpha pathway|downregulation of hypoxia-inducible factor-1alpha signalling pathway						bf	2013-04-18T13:28:25Z						biological_process											owl:Class	
GO:0042478	biolink:NamedThing	regulation of eye photoreceptor cell development	Any process that modulates the frequency, rate or extent of eye photoreceptor development.	got7fsn_ti	regulation of eye photoreceptor development													biological_process											owl:Class	
GO:0015908	biolink:NamedThing	fatty acid transport	The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.	got7fsn_ti														biological_process											owl:Class	
GO:0061888	biolink:NamedThing	regulation of astrocyte activation	Any process that modulates the frequency, rate or extent of astrocyte activation.	got7fsn_ti							dph	2017-06-01T22:26:29Z						biological_process											owl:Class	
GO:0090368	biolink:NamedThing	regulation of ornithine metabolic process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.	got7fsn_ti							tb	2010-07-12T11:14:12Z						biological_process											owl:Class	
GO:0003371	biolink:NamedThing	establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.	got7fsn_ti							dph	2009-12-08T05:42:46Z						biological_process											owl:Class	
CL:0000850	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000268	biolink:NamedThing	positive regulation of blood coagulation, intrinsic pathway	Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway.	got7fsn_ti							mah	2010-11-23T11:45:51Z						biological_process											owl:Class	
GO:0110079	biolink:NamedThing	regulation of placenta blood vessel development	Any process that modulates the frequency, rate or extent of placenta blood vessel development.	got7fsn_ti							kmv	2018-02-01T14:49:12Z						biological_process											owl:Class	
CHEBI:16247	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015153	biolink:NamedThing	rhamnose transmembrane transporter activity	Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.	got7fsn_ti	ATP-dependent rhamnose transmembrane transporter activity|ATPase-coupled rhamnose transmembrane transporter activity|rhamnose-transporting ATPase activity	https://github.com/geneontology/go-ontology/issues/17289									GO:0033297	RHEA:34995		molecular_function											owl:Class	
GO:0015762	biolink:NamedThing	rhamnose transmembrane transport	The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.	got7fsn_ti	rhamnose transport													biological_process											owl:Class	
GO:1904835	biolink:NamedThing	dorsal root ganglion morphogenesis	The developmental process by which a dorsal root ganglion is generated and organized.	got7fsn_ti	spinal ganglion part of peripheral nervous system morphogenesis|ganglion spinalis morphogenesis|spinal ganglion morphogenesis|DRG morphogenesis|dorsal root ganglia morphogenesis|ganglion spinale morphogenesis|posterior root ganglion morphogenesis|ganglion of dorsal root morphogenesis|ganglion sensorium nervi spinalis morphogenesis						bf	2015-12-01T16:41:17Z						biological_process											owl:Class	
CL:1000050	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035727	biolink:NamedThing	lysophosphatidic acid binding	Binding to lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors.	got7fsn_ti	LPA binding						bf	2011-03-10T03:00:05Z						molecular_function											owl:Class	
GO:2000631	biolink:NamedThing	regulation of pre-miRNA processing	Any process that modulates the frequency, rate or extent of pre-microRNA processing.	got7fsn_ti	regulation of pre-microRNA processing						dph	2011-04-18T03:50:16Z						biological_process											owl:Class	
GO:0070241	biolink:NamedThing	positive regulation of activated T cell autonomous cell death	Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death.	got7fsn_ti	positive regulation of activated T cell apoptosis|positive regulation of activated T lymphocyte autonomous cell death|stimulation of activated T cell autonomous cell death|positive regulation of activated T-lymphocyte autonomous cell death|upregulation of activated T cell autonomous cell death|up regulation of activated T cell autonomous cell death|activation of activated T cell autonomous cell death|positive regulation of activated cell autonomous cell death|up-regulation of activated T cell autonomous cell death|positive regulation of activated T-cell autonomous cell death|positive regulation of ACAD													biological_process											owl:Class	
GO:0080092	biolink:NamedThing	regulation of pollen tube growth	Any process that modulates the frequency, rate or extent of pollen tube growth.	got7fsn_ti							dhl	2009-04-22T04:41:29Z						biological_process											owl:Class	
GO:0009333	biolink:NamedThing	cysteine synthase complex	Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A.	got7fsn_ti														cellular_component											owl:Class	
CL:0000219	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009868	biolink:NamedThing	jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway	The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance.	got7fsn_ti	jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)|jasmonic acid and ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)													biological_process											owl:Class	
GO:0032260	biolink:NamedThing	response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.	got7fsn_ti	response to jasmonic acid stimulus during jasmonic acid and ethylene-dependent systemic resistance													biological_process											owl:Class	
CHEBI:35235	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001283	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015351	biolink:NamedThing	bilirubin secondary active transmembrane transporter activity	Enables the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	bilitranslocase|bilirubin porter activity													molecular_function											owl:Class	
GO:1904259	biolink:NamedThing	regulation of basement membrane assembly involved in embryonic body morphogenesis	Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.	got7fsn_ti							als	2015-05-21T09:20:43Z						biological_process											owl:Class	
GO:1905874	biolink:NamedThing	regulation of postsynaptic density organization	Any process that modulates the frequency, rate or extent of postsynaptic density organization.	got7fsn_ti	regulation of PSD organization|regulation of post synaptic density organization|regulation of postsynaptic density organisation|regulation of post-synaptic density organization						sl	2017-01-27T19:53:32Z						biological_process											owl:Class	
GO:0034380	biolink:NamedThing	high-density lipoprotein particle assembly	The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.	got7fsn_ti	HDL assembly													biological_process											owl:Class	
GO:0042943	biolink:NamedThing	D-amino acid transmembrane transporter activity	Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.	got7fsn_ti	D-amino acid transporter activity													molecular_function											owl:Class	
GO:0042940	biolink:NamedThing	D-amino acid transport	The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0002907	biolink:NamedThing	positive regulation of mature B cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.	got7fsn_ti	upregulation of mature B cell apoptosis|up-regulation of mature B cell apoptosis|stimulation of mature B cell apoptosis|activation of mature B cell apoptosis|positive regulation of mature B cell apoptosis|up regulation of mature B cell apoptosis													biological_process											owl:Class	
GO:1904179	biolink:NamedThing	positive regulation of adipose tissue development	Any process that activates or increases the frequency, rate or extent of adipose tissue development.	got7fsn_ti	up-regulation of adipogenesis|upregulation of adipogenesis|upregulation of adipose tissue development|activation of adipogenesis|up regulation of adipose tissue development|positive regulation of adipogenesis|up regulation of adipogenesis|up-regulation of adipose tissue development|activation of adipose tissue development						sl	2015-04-29T20:01:13Z						biological_process											owl:Class	
GO:1903061	biolink:NamedThing	positive regulation of protein lipidation	Any process that activates or increases the frequency, rate or extent of protein lipidation.	got7fsn_ti	positive regulation of lipid:protein modification|up-regulation of protein amino acid lipidation|upregulation of lipid:protein modification|up regulation of lipid:protein modification|up-regulation of protein lipidation|upregulation of protein amino acid lipidation|activation of protein lipidation|activation of protein amino acid lipidation|upregulation of protein lipidation|up-regulation of lipid:protein modification|positive regulation of protein amino acid lipidation|up regulation of protein lipidation|up regulation of protein amino acid lipidation|activation of lipid:protein modification						rph	2014-05-28T13:21:31Z						biological_process											owl:Class	
GO:1902798	biolink:NamedThing	positive regulation of snoRNA processing	Any process that activates or increases the frequency, rate or extent of snoRNA processing.	got7fsn_ti	upregulation of snoRNA processing|up regulation of snoRNA processing|activation of snoRNA processing|up-regulation of snoRNA processing						mah	2014-03-24T12:47:20Z						biological_process											owl:Class	
GO:1905366	biolink:NamedThing	negative regulation of intralumenal vesicle formation	Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation.	got7fsn_ti	downregulation of endosome membrane budding|down-regulation of intralumenal vesicle formation|downregulation of intralumenal vesicle formation|down regulation of endosome membrane budding|down regulation of intralumenal vesicle formation|down-regulation of endosome membrane budding|negative regulation of endosome membrane budding|inhibition of endosome membrane budding|inhibition of intralumenal vesicle formation						bc	2016-08-16T12:00:09Z						biological_process											owl:Class	
GO:0051794	biolink:NamedThing	regulation of timing of catagen	Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.	got7fsn_ti	regulation of catagen													biological_process											owl:Class	
GO:0015765	biolink:NamedThing	methylgalactoside transport	The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.	got7fsn_ti														biological_process											owl:Class	
GO:0042765	biolink:NamedThing	GPI-anchor transamidase complex	An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor.	got7fsn_ti	GPIT complex				Note that this term should not be confused with 'glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506', which represents a distinct complex with a different catalytic activity.									cellular_component											owl:Class	
GO:2000143	biolink:NamedThing	negative regulation of DNA-templated transcription, initiation	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.	got7fsn_ti	negative regulation of DNA-dependent transcription, initiation|negative regulation of initiation of DNA-dependent transcription|negative regulation of transcription initiation, DNA-dependent						mah	2010-10-01T09:11:40Z						biological_process											owl:Class	
GO:1900011	biolink:NamedThing	negative regulation of corticotropin-releasing hormone receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity.	got7fsn_ti	down regulation of corticotropin-releasing hormone receptor activity|negative regulation of adrenocorticotropin-releasing hormone receptor activity|down regulation of CRF receptor activity|negative regulation of CRF receptor activity|down regulation of CRH receptor activity|down regulation of adrenocorticotropin-releasing hormone receptor activity|negative regulation of corticotropin-releasing factor receptor activity|negative regulation of CRH receptor activity|down regulation of corticotropin-releasing factor receptor activity						pr	2012-01-10T02:27:27Z						biological_process											owl:Class	
GO:0043253	biolink:NamedThing	chloroplast ribosome	A ribosome contained within a chloroplast.	got7fsn_ti														cellular_component											owl:Class	
GO:0035435	biolink:NamedThing	phosphate ion transmembrane transport	The process in which a phosphate is transported across a membrane.	got7fsn_ti	phosphate ion membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T11:24:06Z						biological_process											owl:Class	
GO:0072040	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.	got7fsn_ti	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis						mah	2010-01-25T03:09:30Z						biological_process											owl:Class	
GO:0015098	biolink:NamedThing	molybdate ion transmembrane transporter activity	Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid.	got7fsn_ti	molybdate transporter activity													molecular_function											owl:Class	
GO:0090416	biolink:NamedThing	nicotinate transmembrane transporter activity	Enables the transfer of nicotinate from one side of a membrane to the other.	got7fsn_ti							tb	2011-10-19T11:09:59Z				Reactome:R-HSA-8869603		molecular_function											owl:Class	
GO:2001142	biolink:NamedThing	nicotinate transport	The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2011-10-18T05:09:50Z						biological_process											owl:Class	
GO:2001210	biolink:NamedThing	regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.	got7fsn_ti	regulation of isopentenyl diphosphate synthesis, mevalonate pathway|regulation of isopentenyl diphosphate formation, mevalonate pathway|regulation of acetate-mevalonate pathway|regulation of Ac-MVA pathway|regulation of isopentenyl diphosphate anabolism, mevalonate pathway						bf	2011-11-15T10:53:42Z						biological_process											owl:Class	
GO:1904847	biolink:NamedThing	regulation of cell chemotaxis to fibroblast growth factor	Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.	got7fsn_ti							rph	2015-12-10T12:04:01Z						biological_process											owl:Class	
GO:1901888	biolink:NamedThing	regulation of cell junction assembly	Any process that modulates the frequency, rate or extent of cell junction assembly.	got7fsn_ti							tb	2013-02-06T19:40:32Z						biological_process											owl:Class	
GO:1901390	biolink:NamedThing	positive regulation of transforming growth factor beta activation	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation.	got7fsn_ti	up regulation of TGF-B activation|activation of L-TGF-beta activation|up regulation of TGFbeta activation|up-regulation of L-TGF-beta activation|positive regulation of TGF-B activation|positive regulation of TGFbeta activation|up regulation of TGF-beta activation|positive regulation of L-TGF-beta activation|upregulation of L-TGF-beta activation|upregulation of latent TGF-beta activation|positive regulation of latent TGF-beta activation|activation of TGFB activation|up-regulation of latent TGF-beta activation|up-regulation of TGF-B activation|positive regulation of TGFB activation|up-regulation of TGFB activation|up regulation of latent TGF-beta activation|activation of TGFbeta activation|up-regulation of transforming growth factor beta activation|up regulation of transforming growth factor beta activation|activation of TGF-B activation|upregulation of TGFB activation|up regulation of TGFB activation|up regulation of L-TGF-beta activation|activation of latent TGF-beta activation|up-regulation of TGF-beta activation|upregulation of TGF-beta activation|upregulation of TGFbeta activation|positive regulation of TGF-beta activation|upregulation of transforming growth factor beta activation|activation of TGF-beta activation|activation of transforming growth factor beta activation|upregulation of TGF-B activation|up-regulation of TGFbeta activation						bf	2012-10-01T10:33:26Z						biological_process											owl:Class	
GO:2000433	biolink:NamedThing	positive regulation of cytokinesis, actomyosin contractile ring assembly	Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.	got7fsn_ti	positive regulation of contractile ring assembly						vw	2011-03-03T12:18:43Z						biological_process											owl:Class	
GO:0150067	biolink:NamedThing	regulation of tubulin deacetylase activity	Any process that modulates the frequency, rate or extent of tubulin deacetylase activity.	got7fsn_ti							bc	2018-07-24T10:29:49Z						biological_process											owl:Class	
GO:0015422	biolink:NamedThing	ABC-type oligosaccharide transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in).	got7fsn_ti	ATP-dependent oligosaccharide transmembrane transporter activity|ABC-type oligosaccharide transporter|oligosaccharide-transporting ATPase activity|oligosaccharide ABC transporter|ATPase-coupled oligosaccharide transmembrane transporter activity										GO:0015609	MetaCyc:3.6.3.18-RXN|EC:7.5.2.2		molecular_function											owl:Class	
GO:0015120	biolink:NamedThing	phosphoglycerate transmembrane transporter activity	Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis.	got7fsn_ti														molecular_function											owl:Class	
GO:0015713	biolink:NamedThing	phosphoglycerate transmembrane transport	The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	phosphoglycerate transport													biological_process											owl:Class	
GO:1901529	biolink:NamedThing	positive regulation of anion channel activity	Any process that activates or increases the frequency, rate or extent of anion channel activity.	got7fsn_ti	up regulation of anion channel activity|activation of anion channel activity|upregulation of anion channel activity|up-regulation of anion channel activity						tb	2012-10-23T23:38:50Z						biological_process											owl:Class	
GO:0030994	biolink:NamedThing	primary cell septum disassembly	Dissolution of the primary septum during cell separation.	got7fsn_ti	primary cell septum hydrolysis|hydrolysis of primary cell septum|primary septum hydrolysis													biological_process											owl:Class	
GO:0015226	biolink:NamedThing	carnitine transmembrane transporter activity	Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	got7fsn_ti	vitamin Bt transporter activity											Reactome:R-HSA-549297|Reactome:R-HSA-5625674|Reactome:R-HSA-164967|Reactome:R-HSA-165026		molecular_function											owl:Class	
GO:1902603	biolink:NamedThing	carnitine transmembrane transport	The directed movement of carnitine across a membrane.	got7fsn_ti							pr	2013-12-20T11:09:11Z						biological_process											owl:Class	
GO:0060217	biolink:NamedThing	hemangioblast cell differentiation	The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.	got7fsn_ti														biological_process											owl:Class	
GO:1901627	biolink:NamedThing	negative regulation of postsynaptic membrane organization	Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization.	got7fsn_ti	down regulation of postsynaptic membrane organization|negative regulation of post-synaptic membrane organization|downregulation of postsynaptic membrane organization|negative regulation of postsynaptic membrane organisation|downregulation of postsynaptic membrane organisation|down-regulation of postsynaptic membrane organization|down-regulation of postsynaptic membrane organisation|inhibition of postsynaptic membrane organization|inhibition of postsynaptic membrane organisation|down regulation of postsynaptic membrane organisation						ans	2012-11-15T11:40:20Z						biological_process											owl:Class	
GO:0019003	biolink:NamedThing	GDP binding	Binding to GDP, guanosine 5'-diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0015135	biolink:NamedThing	glucuronate transmembrane transporter activity	Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	got7fsn_ti														molecular_function											owl:Class	
GO:0015738	biolink:NamedThing	glucuronate transmembrane transport	The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	glucuronate transport													biological_process											owl:Class	
GO:0031924	biolink:NamedThing	vitamin B6 transmembrane transporter activity	Enables the transfer of any of the vitamin B6 compounds, pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate, from one side of a membrane to the other.	got7fsn_ti	vitamin B6 transporter activity													molecular_function											owl:Class	
GO:0019549	biolink:NamedThing	glutamate catabolic process to succinate via succinate semialdehyde	The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase.	got7fsn_ti	glutamate breakdown to succinate|glutamate degradation to succinate|glutamate catabolic process to succinate via pyruvate-dependent GABA-transaminase activity				While mammals only have 2-oxoglutarate-dependent GABA-transaminase, both 2-oxoglutarate-dependent and pyruvate-dependent GABA-transaminase activities have been detected in plants.							MetaCyc:PWY-4321		biological_process											owl:Class	
GO:0060785	biolink:NamedThing	regulation of apoptosis involved in tissue homeostasis	Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.	got7fsn_ti							dph	2009-07-31T01:49:54Z						biological_process											owl:Class	
GO:0070014	biolink:NamedThing	sucrase-isomaltase complex	A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.	got7fsn_ti	oligo-1,6-glucosidase complex											Wikipedia:Sucrase-isomaltase		cellular_component											owl:Class	
GO:1904624	biolink:NamedThing	regulation of glycine secretion, neurotransmission	Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission.	got7fsn_ti							hjd	2015-08-27T20:03:38Z						biological_process											owl:Class	
GO:0051282	biolink:NamedThing	regulation of sequestering of calcium ion	Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.	got7fsn_ti	regulation of calcium ion (Ca2+) storage|regulation of storage of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) sequestering|regulation of retention of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) sequestration|regulation of sequestration of calcium ion (Ca2+)|regulation of sequestering of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) retention													biological_process											owl:Class	
GO:1905819	biolink:NamedThing	negative regulation of chromosome separation	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.	got7fsn_ti	down regulation of chromosome separation|negative regulation of rDNA separation|downregulation of rDNA separation|downregulation of chromatid release|negative regulation of chromatid release|inhibition of chromatid release|inhibition of rDNA separation|inhibition of chromosome separation|down regulation of rDNA separation|down-regulation of rDNA separation|down regulation of chromatid release|downregulation of chromosome separation|down-regulation of chromosome separation|down-regulation of chromatid release						bhm	2017-01-13T13:55:27Z						biological_process											owl:Class	
GO:0060391	biolink:NamedThing	positive regulation of SMAD protein signal transduction	Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	got7fsn_ti	positive regulation of SMAD protein nuclear translocation|positive regulation of SMAD protein import into nucleus													biological_process											owl:Class	
GO:1904745	biolink:NamedThing	Atg1/ULK1 kinase complex assembly	The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex.	got7fsn_ti	ATG1 kinase complex assembly|ULK1-ATG13-FIP200 complex formation|ULK1-ATG13-FIP200 complex assembly|ULK1-ATG13-RB1CC1 complex formation|ULK1 signaling complex assembly|ATG1/ULK1 signaling complex formation|ULK1-ATG13-RB1CC1 complex assembly|Atg1p signalling complex formation|ULK1 signaling complex formation|ATG1-ATG13 complex formation|ATG1/ULK1 signaling complex assembly|Atg1p signalling complex assembly|ATG1/ULK1 kinase complex formation|ATG1-ATG13 complex assembly|ATG1 kinase complex formation						dph	2015-10-19T12:33:08Z						biological_process											owl:Class	
GO:0015248	biolink:NamedThing	sterol transporter activity	Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti												Reactome:R-HSA-8868402|Reactome:R-HSA-5679145|Reactome:R-HSA-5250531|Reactome:R-HSA-265783|Reactome:R-HSA-5679101|RHEA:39747|Reactome:R-HSA-8867667		molecular_function											owl:Class	
GO:0017145	biolink:NamedThing	stem cell division	The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.	got7fsn_ti	stem cell renewal													biological_process											owl:Class	
GO:0070562	biolink:NamedThing	regulation of vitamin D receptor signaling pathway	Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity.	got7fsn_ti	regulation of VDR signaling pathway|regulation of vitamin D receptor signalling pathway						mah	2009-04-14T01:46:03Z						biological_process											owl:Class	
GO:0021525	biolink:NamedThing	lateral motor column neuron differentiation	The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.	got7fsn_ti														biological_process											owl:Class	
GO:0060784	biolink:NamedThing	regulation of cell proliferation involved in tissue homeostasis	Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.	got7fsn_ti							dph	2009-07-31T01:46:28Z						biological_process											owl:Class	
GO:1901860	biolink:NamedThing	positive regulation of mitochondrial DNA metabolic process	Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.	got7fsn_ti	upregulation of mtDNA metabolism|up-regulation of mtDNA metabolism|activation of mtDNA metabolism|up regulation of mtDNA metabolism|positive regulation of mtDNA metabolic process|positive regulation of mtDNA metabolism|upregulation of mtDNA metabolic process|up-regulation of mitochondrial DNA metabolism|upregulation of mitochondrial DNA metabolism|activation of mitochondrial DNA metabolic process|activation of mtDNA metabolic process|upregulation of mitochondrial DNA metabolic process|activation of mitochondrial DNA metabolism|up regulation of mitochondrial DNA metabolic process|up regulation of mtDNA metabolic process|up regulation of mitochondrial DNA metabolism|positive regulation of mitochondrial DNA metabolism|up-regulation of mtDNA metabolic process|up-regulation of mitochondrial DNA metabolic process						yaf	2013-02-01T10:05:14Z						biological_process											owl:Class	
GO:1902115	biolink:NamedThing	regulation of organelle assembly	Any process that modulates the frequency, rate or extent of organelle assembly.	got7fsn_ti							pr	2013-05-14T09:43:21Z						biological_process											owl:Class	
CHEBI:16113	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000100	biolink:NamedThing	S-methylmethionine transmembrane transporter activity	Enables the transfer of S-methylmethionine from one side of a membrane to the other.	got7fsn_ti	S-methylmethionine permease activity|S-methylmethionine transporter activity										GO:0015178			molecular_function											owl:Class	
GO:0015806	biolink:NamedThing	S-methylmethionine transport	The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:2000330	biolink:NamedThing	positive regulation of T-helper 17 cell lineage commitment	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment.	got7fsn_ti	positive regulation of Th17 cell lineage commitment|positive regulation of Th17 fate commitment|positive regulation of T-helper 17 cell fate commitment						mah	2011-01-19T09:32:16Z						biological_process											owl:Class	
GO:0043417	biolink:NamedThing	negative regulation of skeletal muscle tissue regeneration	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.	got7fsn_ti	down-regulation of skeletal muscle regeneration|inhibition of skeletal muscle regeneration|down regulation of skeletal muscle regeneration|downregulation of skeletal muscle regeneration													biological_process											owl:Class	
GO:0045699	biolink:NamedThing	positive regulation of synergid differentiation	Any process that activates or increases the frequency, rate or extent of synergid cell differentiation.	got7fsn_ti	upregulation of synergid differentiation|stimulation of synergid differentiation|activation of synergid differentiation|positive regulation of synergid cell differentiation|up-regulation of synergid differentiation|up regulation of synergid differentiation													biological_process											owl:Class	
GO:0045628	biolink:NamedThing	regulation of T-helper 2 cell differentiation	Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation.	got7fsn_ti	regulation of T-helper 2 cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1903750	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.	got7fsn_ti	regulation of hydrogen peroxide-induced apoptosis|regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|regulation of H2O2-induced intrinsic apoptotic signaling pathway|regulation of intrinsic apoptotic signaling pathway in response to H2O2						krc	2014-12-12T23:04:28Z						biological_process											owl:Class	
RO:0002338	biolink:NamedThing	has target start location		got7fsn_ti												RO:0002338|RO:0002338		external|external									has_target_start_location|has_target_start_location		owl:ObjectProperty	
results_in_movement_of	biolink:NamedThing	results in movement of		got7fsn_ti												RO:0002565|RO:0002565		external|external									results_in_movement_of|results_in_movement_of		owl:ObjectProperty	
results_in_structural_organization_of	biolink:NamedThing	results in structural organization of		got7fsn_ti												RO:0002355|RO:0002355		external|external									results_in_structural_organization_of|results_in_structural_organization_of		owl:ObjectProperty	
RO:0002014	biolink:NamedThing	has negative regulatory component activity		got7fsn_ti												RO:0002014|RO:0002014		external|external									has_negative_regulatory_component_activity|has_negative_regulatory_component_activity		owl:ObjectProperty	
RO:0002131	biolink:NamedThing	overlaps		got7fsn_ti												RO:0002131|RO:0002131		external|external									overlaps|overlaps		owl:ObjectProperty	
GOREL:0000040	biolink:NamedThing	results_in		got7fsn_ti					This relation is currently used to connect two regulation processes p1 and p2, such that if r1 regulates p1 and r2 regulates p2, and r1 results_in r2 then the regulation of p1 is required for the regulation of p2. For an example of use, see GO:0035958 'regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter'. Note that a precise definition of this relation is under discussion. After it has been formalized it will be added to RO, where it will have a RO ID. Note that the existing identifier and label are subject to change.|This relation is currently used to connect two regulation processes p1 and p2, such that if r1 regulates p1 and r2 regulates p2, and r1 results_in r2 then the regulation of p1 is required for the regulation of p2. For an example of use, see GO:0035958 'regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter'. Note that a precise definition of this relation is under discussion. After it has been formalized it will be added to RO, where it will have a RO ID. Note that the existing identifier and label are subject to change.		cjm|cjm	2012-03-14T10:35:44Z|2012-03-14T10:35:44Z				GOREL:0000040|GOREL:0000040		external|external									results_in|results_in		owl:ObjectProperty	
RO:0002344	biolink:NamedThing	results in transport to from or in		got7fsn_ti												RO:0002344|RO:0002344		external|external									results_in_transport_to_from_or_in|results_in_transport_to_from_or_in		owl:ObjectProperty	
RO:0002405	biolink:NamedThing	immediately causally downstream of		got7fsn_ti												RO:0002405|RO:0002405		external|external									immediately_causally_downstream_of|immediately_causally_downstream_of		owl:ObjectProperty	
RO:0002298	biolink:NamedThing	results in morphogenesis of		got7fsn_ti												RO:0002298|RO:0002298		external|external									results_in_morphogenesis_of|results_in_morphogenesis_of		owl:ObjectProperty	
RO:0002334	biolink:NamedThing	regulated by		got7fsn_ti												RO:0002334|RO:0002334		external|external									regulated_by|regulated_by		owl:ObjectProperty	
RO:0004008	biolink:NamedThing	has primary output		got7fsn_ti												RO:0004008|RO:0004008		external|external									has_primary_output|has_primary_output		owl:ObjectProperty	
exports	biolink:NamedThing	exports		got7fsn_ti												RO:0002345|RO:0002345		external|external									exports|exports		owl:ObjectProperty	
coincident_with	biolink:NamedThing	coincident with		got7fsn_ti												RO:0002008|RO:0002008		external|external									coincident_with|coincident_with		owl:ObjectProperty	
RO:0002335	biolink:NamedThing	negatively regulated by		got7fsn_ti												RO:0002335|RO:0002335		external|external									negatively_regulated_by|negatively_regulated_by		owl:ObjectProperty	
RO:0000053	biolink:NamedThing	bearer of		got7fsn_ti												RO:0000053|RO:0000053		external|external									bearer_of|bearer_of		owl:ObjectProperty	
RO:0002356	biolink:NamedThing	results in specification of		got7fsn_ti												RO:0002356|RO:0002356		external|external									results_in_specification_of|results_in_specification_of		owl:ObjectProperty	
has_start_location	biolink:NamedThing	has start location		got7fsn_ti												RO:0002231|RO:0002231		external|external									has_start_location|has_start_location		owl:ObjectProperty	
has_primary_input_or_output	biolink:NamedThing	has primary input or output		got7fsn_ti												RO:0004007|RO:0004007		external|external									has_primary_input_or_output|has_primary_input_or_output		owl:ObjectProperty	
RO:0002427	biolink:NamedThing	causally downstream of or within		got7fsn_ti												RO:0002427|RO:0002427		external|external									causally_downstream_of_or_within|causally_downstream_of_or_within		owl:ObjectProperty	
RO:0002305	biolink:NamedThing	causally upstream of, negative effect		got7fsn_ti												RO:0002305|RO:0002305		external|external									causally_upstream_of,_negative_effect|causally_upstream_of,_negative_effect		owl:ObjectProperty	
RO:0002348	biolink:NamedThing	results in commitment to		got7fsn_ti												RO:0002348|RO:0002348		external|external									results_in_commitment_to|results_in_commitment_to		owl:ObjectProperty	
RO:0002304	biolink:NamedThing	causally upstream of, positive effect		got7fsn_ti												RO:0002304|RO:0002304		external|external									causally_upstream_of,_positive_effect|causally_upstream_of,_positive_effect		owl:ObjectProperty	
GOREL:0002005	biolink:NamedThing	results_in_fusion_of		got7fsn_ti												GOREL:0002005|GOREL:0002005											results_in_fusion_of|results_in_fusion_of		owl:ObjectProperty	
RO:0002411	biolink:NamedThing	causally upstream of		got7fsn_ti												RO:0002411|RO:0002411		external|external									causally_upstream_of|causally_upstream_of		owl:ObjectProperty	
RO:0002295	biolink:NamedThing	results in developmental progression of		got7fsn_ti												RO:0002295|RO:0002295		external|external									results_in_developmental_progression_of|results_in_developmental_progression_of		owl:ObjectProperty	
RO:0002091	biolink:NamedThing	starts_during		got7fsn_ti												RO:0002091|RO:0002091		external|external									starts_during|starts_during		owl:ObjectProperty	
RO:0002505	biolink:NamedThing	has intermediate		got7fsn_ti												RO:0002505|RO:0002505		external|external									has_intermediate|has_intermediate		owl:ObjectProperty	
RO:0002315	biolink:NamedThing	results in acquisition of features of		got7fsn_ti												RO:0002315|RO:0002315		external|external									results_in_acquisition_of_features_of|results_in_acquisition_of_features_of		owl:ObjectProperty	
RO:0002234	biolink:NamedThing	has output		got7fsn_ti												RO:0002234|RO:0002234		external|external									has_output|has_output		owl:ObjectProperty	
RO:0002224	biolink:NamedThing	starts with		got7fsn_ti												RO:0002224|RO:0002224		external|external									starts_with|starts_with		owl:ObjectProperty	
RO:0002313	biolink:NamedThing	transports or maintains localization of		got7fsn_ti												RO:0002313|RO:0002313		external|external									transports_or_maintains_localization_of|transports_or_maintains_localization_of		owl:ObjectProperty	
RO:0002230	biolink:NamedThing	ends with		got7fsn_ti												RO:0002230|RO:0002230		external|external									ends_with|ends_with		owl:ObjectProperty	
RO:0002090	biolink:NamedThing	immediately_precedes		got7fsn_ti												RO:0002090|RO:0002090		external|external									immediately_precedes|immediately_precedes		owl:ObjectProperty	
BFO:0000066	biolink:NamedThing	occurs in		got7fsn_ti												BFO:0000066|BFO:0000066		external|external									occurs_in|occurs_in		owl:ObjectProperty	
RO:0002299	biolink:NamedThing	results in maturation of		got7fsn_ti												RO:0002299|RO:0002299		external|external									results_in_maturation_of|results_in_maturation_of		owl:ObjectProperty	
RO:0002343	biolink:NamedThing	results in growth of		got7fsn_ti												RO:0002343|RO:0002343		external|external									results_in_growth_of|results_in_growth_of		owl:ObjectProperty	
RO:0002232	biolink:NamedThing	has end location		got7fsn_ti												RO:0002232|RO:0002232		external|external									has_end_location|has_end_location		owl:ObjectProperty	
RO:0002016	biolink:NamedThing	has necessary component activity		got7fsn_ti												RO:0002016|RO:0002016		external|external									has_necessary_component_activity|has_necessary_component_activity		owl:ObjectProperty	
RO:0002339	biolink:NamedThing	has target end location		got7fsn_ti												RO:0002339|RO:0002339		external|external									has_target_end_location|has_target_end_location		owl:ObjectProperty	
has_component	biolink:NamedThing	has component		got7fsn_ti												RO:0002180|RO:0002180		external|external									has_component|has_component		owl:ObjectProperty	
imports	biolink:NamedThing	imports		got7fsn_ti												RO:0002340|RO:0002340		external|external									imports|imports		owl:ObjectProperty	
OBO:go/extensions/ro_pending#results_in_transport_through	biolink:NamedThing	obsolete results_in_transport_through		got7fsn_ti										True|True															owl:ObjectProperty	
RO:0002087	biolink:NamedThing	immediately_preceded_by		got7fsn_ti												RO:0002087|RO:0002087		external|external									immediately_preceded_by|immediately_preceded_by		owl:ObjectProperty	
RO:0002215	biolink:NamedThing	capable of		got7fsn_ti												RO:0002215|RO:0002215		external|external									capable_of|capable_of		owl:ObjectProperty	
RO:0002296	biolink:NamedThing	results in development of		got7fsn_ti												RO:0002296|RO:0002296		external|external									results_in_development_of|results_in_development_of		owl:ObjectProperty	
RO:0002233	biolink:NamedThing	has input		got7fsn_ti												RO:0002233|RO:0002233		external|external									has_input|has_input		owl:ObjectProperty	
RO:0002418	biolink:NamedThing	causally upstream of or within		got7fsn_ti												RO:0002418|RO:0002418		external|external									causally_upstream_of_or_within|causally_upstream_of_or_within		owl:ObjectProperty	
OBO:go/extensions/ro_pending#alters_location_of	biolink:NamedThing	obsolete alters location of		got7fsn_ti										True|True															owl:ObjectProperty	
RO:0002013	biolink:NamedThing	has regulatory component activity		got7fsn_ti												RO:0002013|RO:0002013		external|external									has_regulatory_component_activity|has_regulatory_component_activity		owl:ObjectProperty	
RO:0002336	biolink:NamedThing	positively regulated by		got7fsn_ti												RO:0002336|RO:0002336		external|external									positively_regulated_by|positively_regulated_by		owl:ObjectProperty	
has_intermediate	biolink:NamedThing	obsolete has intermediate		got7fsn_ti					Replaced by RO_0002505.|Replaced by RO_0002505.					True|True		GOREL:0002008|GOREL:0002008											has_intermediate|has_intermediate		owl:ObjectProperty	
participates_in	biolink:NamedThing	participates_in		got7fsn_ti												RO:0000056|RO:0000056		external|external									participates_in|participates_in		owl:ObjectProperty	
has_primary_input	biolink:NamedThing	has primary input		got7fsn_ti												RO:0004009|RO:0004009		external|external									has_primary_input|has_primary_input		owl:ObjectProperty	
RO:0002349	biolink:NamedThing	results in determination of		got7fsn_ti												RO:0002349|RO:0002349		external|external									results_in_determination_of|results_in_determination_of		owl:ObjectProperty	
RO:0002220	biolink:NamedThing	adjacent to		got7fsn_ti												RO:0002220|RO:0002220		external|external									adjacent_to|adjacent_to		owl:ObjectProperty	
RO:0002341	biolink:NamedThing	results in transport along		got7fsn_ti												RO:0002341|RO:0002341		external|external									results_in_transport_along|results_in_transport_along		owl:ObjectProperty	
RO:0002007	biolink:NamedThing	bounding layer of		got7fsn_ti												RO:0002007|RO:0002007		external|external									bounding_layer_of|bounding_layer_of		owl:ObjectProperty	
RO:0002342	biolink:NamedThing	results in transport across		got7fsn_ti												RO:0002342|RO:0002342		external|external									results_in_transport_across|results_in_transport_across		owl:ObjectProperty	
RO:0002353	biolink:NamedThing	output of		got7fsn_ti												RO:0002353|RO:0002353		external|external									output_of|output_of		owl:ObjectProperty	
RO:0003000	biolink:NamedThing	produces		got7fsn_ti												RO:0003000|RO:0003000		external|external									produces|produces		owl:ObjectProperty	
RO:0002297	biolink:NamedThing	results in formation of		got7fsn_ti												RO:0002297|RO:0002297		external|external									results_in_formation_of|results_in_formation_of		owl:ObjectProperty	
BFO:0000063	biolink:NamedThing	precedes		got7fsn_ti												BFO:0000063|BFO:0000063		external|external									precedes|precedes		owl:ObjectProperty	
RO:0002332	biolink:NamedThing	regulates levels of		got7fsn_ti												RO:0002332|RO:0002332		external|external									regulates_levels_of|regulates_levels_of		owl:ObjectProperty	
RO:0002160	biolink:NamedThing			got7fsn_ti																									owl:ObjectProperty	
RO:0002162	biolink:NamedThing			got7fsn_ti																									owl:ObjectProperty	
RO:0002216	biolink:NamedThing	capable of part of		got7fsn_ti												RO:0002216|RO:0002216		external|external									capable_of_part_of|capable_of_part_of		owl:ObjectProperty	
results_in_distribution_of	biolink:NamedThing	results_in_distribution_of		got7fsn_ti												GOREL:0002003|GOREL:0002003		external|external									results_in_distribution_of|results_in_distribution_of		owl:ObjectProperty	
BFO:0000062	biolink:NamedThing	preceded by		got7fsn_ti												BFO:0000062|BFO:0000062		external|external									preceded_by|preceded_by		owl:ObjectProperty	
immediately_causally_upstream_of	biolink:NamedThing	immediately causally upstream of		got7fsn_ti												RO:0002412|RO:0002412		external|external									immediately_causally_upstream_of|immediately_causally_upstream_of		owl:ObjectProperty	
RO:0002404	biolink:NamedThing	causally downstream of		got7fsn_ti												RO:0002404|RO:0002404		external|external									causally_downstream_of|causally_downstream_of		owl:ObjectProperty	
RO:0003001	biolink:NamedThing	produced by		got7fsn_ti												RO:0003001|RO:0003001		external|external									produced_by|produced_by		owl:ObjectProperty	
process_has_causal_agent	biolink:NamedThing	process has causal agent		got7fsn_ti												RO:0002608|RO:0002608		external|external									process_has_causal_agent|process_has_causal_agent		owl:ObjectProperty	
GO:1900376	biolink:NamedThing	regulation of secondary metabolite biosynthetic process	Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process.	got7fsn_ti	regulation of secondary metabolite biosynthesis						di	2012-04-17T01:55:23Z						biological_process											owl:Class	
GO:1903771	biolink:NamedThing	positive regulation of beta-galactosidase activity	Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity.	got7fsn_ti	upregulation of hydrolact|up regulation of maxilact|up regulation of beta-D-lactosidase activity|activation of lactozym|up-regulation of beta-D-lactosidase activity|up regulation of oryzatym|up-regulation of sumiklat|up-regulation of beta-galactosidase activity|positive regulation of beta-D-lactosidase activity|positive regulation of beta-D-galactoside galactohydrolase activity|positive regulation of lactose hydrolysis|activation of trilactase activity|up-regulation of beta-D-galactanase activity|upregulation of oryzatym|positive regulation of sumiklat|upregulation of beta-D-galactanase activity|up regulation of beta-lactosidase activity|up-regulation of lactozym|upregulation of exo-(1->4)-beta-D-galactanase activity|positive regulation of maxilact|up-regulation of trilactase activity|up-regulation of beta-D-galactoside galactohydrolase activity|upregulation of trilactase activity|up regulation of exo-(1->4)-beta-D-galactanase activity|upregulation of beta-lactosidase activity|up regulation of beta-D-galactanase activity|activation of beta-D-galactoside galactohydrolase activity|activation of exo-(1->4)-beta-D-galactanase activity|positive regulation of beta-lactosidase activity|activation of beta-D-galactanase activity|upregulation of beta-D-lactosidase activity|activation of hydrolact|upregulation of S 2107|upregulation of maxilact|up regulation of lactose hydrolysis|up-regulation of maxilact|up-regulation of oryzatym|up-regulation of exo-(1->4)-beta-D-galactanase activity|activation of maxilact|activation of oryzatym|activation of beta-D-lactosidase activity|up regulation of trilactase activity|up regulation of hydrolact|positive regulation of beta-D-galactanase activity|positive regulation of lactozym|up-regulation of beta-lactosidase activity|up-regulation of hydrolact|upregulation of lactozym|upregulation of beta-D-galactoside galactohydrolase activity|upregulation of sumiklat|upregulation of lactose hydrolysis|activation of lactose hydrolysis|activation of beta-galactosidase activity|activation of S 2107|positive regulation of trilactase activity|up-regulation of S 2107|up regulation of sumiklat|activation of sumiklat|positive regulation of S 2107|positive regulation of oryzatym|up-regulation of lactose hydrolysis|up regulation of beta-galactosidase activity|activation of beta-lactosidase activity|up regulation of lactozym|up regulation of beta-D-galactoside galactohydrolase activity|up regulation of S 2107|positive regulation of hydrolact|positive regulation of exo-(1->4)-beta-D-galactanase activity|upregulation of beta-galactosidase activity						nc	2015-01-06T10:53:32Z						biological_process											owl:Class	
GO:1900502	biolink:NamedThing	positive regulation of butyryl-CoA catabolic process to butyrate	Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.	got7fsn_ti	up-regulation of butyryl-CoA catabolism to butyrate|positive regulation of butyryl-CoA catabolism to butyrate|up-regulation of butyryl-CoA catabolic process to butyrate|upregulation of butyryl-CoA catabolism to butyrate|activation of butyryl-CoA catabolic process to butyrate|up regulation of butyryl-CoA catabolic process to butyrate|activation of butyryl-CoA catabolism to butyrate|upregulation of butyryl-CoA catabolic process to butyrate|up regulation of butyryl-CoA catabolism to butyrate						tt	2012-05-02T03:56:40Z						biological_process											owl:Class	
GO:1905693	biolink:NamedThing	regulation of phosphatidic acid biosynthetic process	Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process.	got7fsn_ti	regulation of phosphatidic acid formation|regulation of phosphatidic acid biosynthesis|regulation of phosphatidic acid synthesis|regulation of phosphatidic acid anabolism						bc	2016-11-14T14:48:09Z						biological_process											owl:Class	
GO:0120040	biolink:NamedThing	regulation of macrophage proliferation	Any process that modulates the frequency, rate or extent of macrophage proliferation.	got7fsn_ti							krc	2017-05-10T20:38:19Z						biological_process											owl:Class	
GO:1902336	biolink:NamedThing	positive regulation of retinal ganglion cell axon guidance	Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance.	got7fsn_ti	upregulation of retinal ganglion cell axon guidance|positive regulation of retinal ganglion cell axon pathfinding|activation of retinal ganglion cell axon pathfinding|up regulation of retinal ganglion cell axon guidance|activation of retinal ganglion cell axon guidance|upregulation of retinal ganglion cell axon pathfinding|up regulation of retinal ganglion cell axon pathfinding|up-regulation of retinal ganglion cell axon guidance|up-regulation of retinal ganglion cell axon pathfinding						rl	2013-07-29T13:02:25Z						biological_process											owl:Class	
GO:1900735	biolink:NamedThing	positive regulation of flocculation	Any process that activates or increases the frequency, rate or extent of flocculation.	got7fsn_ti	upregulation of flocculation via cell wall protein-carbohydrate interaction|upregulation of flocculation|activation of flocculation|up-regulation of flocculation via cell wall protein-carbohydrate interaction|up regulation of flocculation|activation of flocculation via cell wall protein-carbohydrate interaction|up regulation of flocculation via cell wall protein-carbohydrate interaction|positive regulation of flocculation via cell wall protein-carbohydrate interaction|up-regulation of flocculation						dgf	2012-05-27T08:27:38Z			GO:1900479			biological_process											owl:Class	
GO:1901409	biolink:NamedThing	positive regulation of phosphorylation of RNA polymerase II C-terminal domain	Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.	got7fsn_ti	up regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of CTD domain phosphorylation of RNA polymerase II|up regulation of generation of II(0) form of RNA polymerase II|activation of generation of II(0) form of RNA polymerase II|positive regulation of generation of hyperphosphorylated CTD of RNA polymerase II|up regulation of CTD domain phosphorylation of RNA polymerase II|upregulation of CTD domain phosphorylation of RNA polymerase II|upregulation of phosphorylation of RNA polymerase II C-terminal domain|up-regulation of generation of II(0) form of RNA polymerase II|positive regulation of generation of II(0) form of RNA polymerase II|up-regulation of generation of hyperphosphorylated CTD of RNA polymerase II|activation of generation of hyperphosphorylated CTD of RNA polymerase II|up regulation of phosphorylation of RNA polymerase II C-terminal domain|upregulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of phosphorylation of RNA polymerase II C-terminal domain|positive regulation of CTD domain phosphorylation of RNA polymerase II|positive regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of hyperphosphorylation of RNA polymerase II C-terminal domain|up-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|upregulation of generation of II(0) form of RNA polymerase II|upregulation of generation of hyperphosphorylated CTD of RNA polymerase II|up-regulation of phosphorylation of RNA polymerase II C-terminal domain|up regulation of generation of hyperphosphorylated CTD of RNA polymerase II|up-regulation of CTD domain phosphorylation of RNA polymerase II						vw	2012-10-01T14:41:15Z						biological_process											owl:Class	
GO:1904354	biolink:NamedThing	negative regulation of telomere capping	Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping.	got7fsn_ti	inhibition of telomere capping|down-regulation of telomere end protection|down-regulation of telomere capping|down regulation of telomere capping|down regulation of telomere end protection|negative regulation of telomere end protection|downregulation of telomere capping|downregulation of telomere end protection|inhibition of telomere end protection						nc	2015-06-12T16:51:14Z						biological_process											owl:Class	
GO:0034124	biolink:NamedThing	regulation of MyD88-dependent toll-like receptor signaling pathway	Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.	got7fsn_ti	regulation ofMyD88-dependent TLR signaling pathway|regulation ofMyD88-dependent toll-like receptor signalling pathway													biological_process											owl:Class	
GO:2000396	biolink:NamedThing	negative regulation of ubiquitin-dependent endocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis.	got7fsn_ti	negative regulation of ubiquitin-mediated endocytosis						mah	2011-02-22T11:25:21Z						biological_process											owl:Class	
GO:0010743	biolink:NamedThing	regulation of macrophage derived foam cell differentiation	Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	got7fsn_ti														biological_process											owl:Class	
GO:0034171	biolink:NamedThing	regulation of toll-like receptor 11 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 11 signalling pathway|regulation of TLR11 signaling pathway													biological_process											owl:Class	
GO:0035067	biolink:NamedThing	negative regulation of histone acetylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.	got7fsn_ti	down regulation of histone acetylation|downregulation of histone acetylation|down-regulation of histone acetylation|inhibition of histone acetylation													biological_process											owl:Class	
GO:1900824	biolink:NamedThing	positive regulation of ergot alkaloid biosynthetic process	Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process.	got7fsn_ti	upregulation of ergot alkaloid biosynthesis|up-regulation of ergot alkaloid formation|upregulation of ergot alkaloid formation|positive regulation of ergot alkaloid formation|positive regulation of ergot alkaloid anabolism|up regulation of ergot alkaloid biosynthesis|up regulation of ergot alkaloid anabolism|up-regulation of ergot alkaloid biosynthesis|upregulation of ergot alkaloid synthesis|activation of ergot alkaloid anabolism|up regulation of ergot alkaloid biosynthetic process|positive regulation of ergot alkaloid synthesis|positive regulation of ergot alkaloid biosynthesis|activation of ergot alkaloid biosynthetic process|up-regulation of ergot alkaloid biosynthetic process|activation of ergot alkaloid synthesis|up regulation of ergot alkaloid formation|upregulation of ergot alkaloid anabolism|up-regulation of ergot alkaloid anabolism|upregulation of ergot alkaloid biosynthetic process|activation of ergot alkaloid formation|activation of ergot alkaloid biosynthesis|up-regulation of ergot alkaloid synthesis|up regulation of ergot alkaloid synthesis						di	2012-06-04T11:13:05Z						biological_process											owl:Class	
GO:1900706	biolink:NamedThing	positive regulation of siderophore biosynthetic process	Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process.	got7fsn_ti	up-regulation of siderophore anabolism|up-regulation of siderophore biosynthetic process, peptide formation|up-regulation of siderophore synthesis|up-regulation of siderophore biosynthesis|up-regulation of siderophore biosynthetic process, peptide modification|upregulation of siderophore biosynthetic process|activation of siderophore synthesis|up-regulation of siderochrome biosynthetic process|upregulation of siderophore formation|positive regulation of siderochrome biosynthetic process|up regulation of siderophore anabolism|positive regulation of siderophore anabolism|upregulation of siderophore anabolism|up regulation of siderochrome biosynthesis|up regulation of siderophore synthesis|activation of siderophore anabolism|upregulation of siderophore biosynthetic process, peptide modification|activation of siderochrome biosynthesis|positive regulation of siderochrome biosynthesis|activation of siderophore biosynthetic process, peptide modification|upregulation of siderophore biosynthesis|positive regulation of siderophore synthesis|activation of siderophore biosynthetic process|up regulation of siderophore biosynthetic process, peptide formation|up-regulation of siderophore biosynthetic process|up-regulation of siderochrome biosynthesis|up-regulation of siderophore formation|up regulation of siderophore biosynthetic process, peptide modification|positive regulation of siderophore biosynthetic process, peptide formation|activation of siderophore biosynthesis|upregulation of siderochrome biosynthesis|activation of siderochrome biosynthetic process|up regulation of siderophore formation|upregulation of siderochrome biosynthetic process|activation of siderophore formation|upregulation of siderophore synthesis|positive regulation of siderophore biosynthesis|up regulation of siderochrome biosynthetic process|up regulation of siderophore biosynthesis|positive regulation of siderophore biosynthetic process, peptide modification|positive regulation of siderophore formation|up regulation of siderophore biosynthetic process|activation of siderophore biosynthetic process, peptide formation|upregulation of siderophore biosynthetic process, peptide formation						di	2012-05-22T05:00:00Z						biological_process											owl:Class	
GO:0106042	biolink:NamedThing	negative regulation of GABA-A receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity.	got7fsn_ti							hjd	2017-07-27T18:55:03Z						biological_process											owl:Class	
GO:1904460	biolink:NamedThing	positive regulation of substance P secretion	Any process that activates or increases the frequency, rate or extent of substance P secretion.	got7fsn_ti	upregulation of substance P secretion|activation of substance P secretion|up-regulation of substance P secretion|up regulation of substance P secretion						sl	2015-07-09T19:33:03Z						biological_process											owl:Class	
GO:1902442	biolink:NamedThing	regulation of ripoptosome assembly involved in necroptotic process	Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.	got7fsn_ti	regulation of ripoptosome assembly involved in necroptosis						dph	2013-10-10T17:51:33Z						biological_process											owl:Class	
GO:1902901	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion	Any positive regulation of transcription from RNA polymerase II promoter that is involved in stress response to cadmium ion.	got7fsn_ti	up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of transcription from Pol II promoter involved in stress response to cadmium ion|up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of transcription from Pol II promoter involved in response to cadmium ion stress|up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of global transcription from Pol II promoter involved in response to cadmium ion stress|stimulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|activation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|upregulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|stimulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|stimulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|upregulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|stimulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of transcription from Pol II promoter involved in response to cadmium toxicity|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium ion stress|activation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|activation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|upregulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of global transcription from Pol II promoter involved in response to cadmium toxicity|up-regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|upregulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of global transcription from Pol II promoter involved in stress response to cadmium ion|activation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress						kmv	2014-04-14T18:03:42Z						biological_process											owl:Class	
GO:2000465	biolink:NamedThing	regulation of glycogen (starch) synthase activity	Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity.	got7fsn_ti	regulation of UDP-glycogen synthase activity|regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|regulation of UDPG-glycogen synthetase activity|regulation of glycogen (starch) synthetase activity|regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|regulation of UDPG-glycogen transglucosylase activity|regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|regulation of UDP-glucose-glycogen glucosyltransferase activity						yaf	2011-03-07T04:12:35Z						biological_process											owl:Class	
GO:1904565	biolink:NamedThing	response to 1-oleoyl-sn-glycerol 3-phosphate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.	got7fsn_ti	response to LPA|response to 1-oleoyl lysophosphatidic acid|response to oleoyl-L-alpha-lysophosphatidic acid|response to lysophosphatidic acid|response to oleoyl lysophosphatidic acid						sl	2015-08-19T15:36:48Z						biological_process											owl:Class	
GO:0030805	biolink:NamedThing	regulation of cyclic nucleotide catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.	got7fsn_ti	regulation of cyclic nucleotide degradation|regulation of cyclic nucleotide catabolism|regulation of cyclic nucleotide breakdown													biological_process											owl:Class	
GO:1903290	biolink:NamedThing	obsolete negative regulation of ATP catabolic process	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP catabolic process.	got7fsn_ti	negative regulation of ATP hydrolysis|down-regulation of ATP breakdown|negative regulation of ATP catabolism|inhibition of ATP breakdown|negative regulation of ATP breakdown|down-regulation of ATP catabolism|downregulation of ATP catabolism|inhibition of ATP catabolic process|down-regulation of ATP catabolic process|down regulation of ATP hydrolysis|down-regulation of ATP hydrolysis|down regulation of ATP breakdown|downregulation of ATP breakdown|down regulation of ATP degradation|downregulation of ATP hydrolysis|negative regulation of ATP degradation|down regulation of ATP catabolic process|down-regulation of ATP degradation|inhibition of ATP hydrolysis|inhibition of ATP catabolism|inhibition of ATP degradation|downregulation of ATP degradation|down regulation of ATP catabolism|downregulation of ATP catabolic process				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0032780	rl	2014-08-11T14:36:47Z		True				biological_process											owl:Class	
GO:1903516	biolink:NamedThing	regulation of single strand break repair	Any process that modulates the frequency, rate or extent of single strand break repair.	got7fsn_ti							rl	2014-10-06T10:58:52Z						biological_process											owl:Class	
GO:1903817	biolink:NamedThing	negative regulation of voltage-gated potassium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity.	got7fsn_ti	downregulation of voltage-gated potassium ion channel activity|downregulation of voltage gated potassium channel activity|downregulation of voltage-dependent potassium channel activity|down regulation of voltage-gated potassium channel activity|negative regulation of voltage-gated potassium ion channel activity|downregulation of voltage-sensitive potassium channel|down regulation of voltage-sensitive potassium channel|down regulation of voltage-dependent potassium channel activity|down-regulation of voltage-dependent potassium channel activity|inhibition of voltage-dependent potassium channel activity|down-regulation of voltage gated potassium channel activity|down regulation of voltage gated potassium channel activity|inhibition of voltage-gated potassium channel activity|down-regulation of voltage-gated potassium ion channel activity|down-regulation of voltage-sensitive potassium channel|negative regulation of voltage gated potassium channel activity|inhibition of voltage-sensitive potassium channel|inhibition of voltage-gated potassium ion channel activity|negative regulation of voltage-sensitive potassium channel|down-regulation of voltage-gated potassium channel activity|downregulation of voltage-gated potassium channel activity|inhibition of voltage gated potassium channel activity|down regulation of voltage-gated potassium ion channel activity|negative regulation of voltage-dependent potassium channel activity						sl	2015-01-16T17:22:08Z						biological_process											owl:Class	
GO:0032592	biolink:NamedThing	integral component of mitochondrial membrane	The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to mitochondrial membrane													cellular_component											owl:Class	
GO:0001603	biolink:NamedThing	obsolete vasopressin-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	vasopressin-like receptor activity									True				molecular_function											owl:Class	
GO:0010777	biolink:NamedThing	meiotic mismatch repair involved in reciprocal meiotic recombination	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti														biological_process											owl:Class	
GO:1903243	biolink:NamedThing	negative regulation of cardiac muscle hypertrophy in response to stress	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.	got7fsn_ti	downregulation of cardiac muscle hypertrophy in response to stress|down regulation of cardiac muscle hypertrophy in response to stress|down-regulation of cardiac muscle hypertrophy in response to stress|inhibition of cardiac muscle hypertrophy in response to stress						rl	2014-08-01T16:31:42Z						biological_process											owl:Class	
GO:1904898	biolink:NamedThing	negative regulation of hepatic stellate cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.	got7fsn_ti	downregulation of perisinusoidal cell proliferation|down regulation of hepatic stellate cell proliferation|negative regulation of perisinusoidal cell proliferation|down-regulation of hepatic stellate cell proliferation|inhibition of Ito cell proliferation|down-regulation of Ito cell proliferation|downregulation of Ito cell proliferation|down regulation of perisinusoidal cell proliferation|downregulation of hepatic perisinusoidal cell proliferation|down-regulation of perisinusoidal cell proliferation|inhibition of hepatic stellate cell proliferation|down-regulation of hepatic perisinusoidal cell proliferation|negative regulation of Ito cell proliferation|down regulation of Ito cell proliferation|negative regulation of hepatic perisinusoidal cell proliferation|down regulation of hepatic perisinusoidal cell proliferation|inhibition of perisinusoidal cell proliferation|inhibition of hepatic perisinusoidal cell proliferation|downregulation of hepatic stellate cell proliferation						sl	2016-01-14T15:57:06Z						biological_process											owl:Class	
GO:0052139	biolink:NamedThing	obsolete negative chemotaxis in host	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative chemotaxis within host	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0071268	biolink:NamedThing	homocysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid.	got7fsn_ti	homocysteine biosynthesis|homocysteine formation|homocysteine anabolism|homocysteine synthesis						mah	2009-12-09T05:32:48Z						biological_process											owl:Class	
GO:0072369	biolink:NamedThing	obsolete regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of lipid transport by positive regulation of transcription from an RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:23:53Z		True				biological_process											owl:Class	
GO:0003252	biolink:NamedThing	negative regulation of cell proliferation involved in heart valve morphogenesis	Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.	got7fsn_ti							dph	2009-10-13T02:10:39Z						biological_process											owl:Class	
GO:1904752	biolink:NamedThing	regulation of vascular associated smooth muscle cell migration	Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration.	got7fsn_ti	regulation of vascular smooth muscle cell migration						rph	2015-10-19T15:49:52Z						biological_process											owl:Class	
GO:1902590	biolink:NamedThing	multi-organism organelle organization	An organelle organization which involves another organism.	got7fsn_ti	multi organism organelle organization						jl	2013-12-19T15:26:08Z						biological_process											owl:Class	
GO:0030415	biolink:NamedThing	obsolete carboxypeptidase A inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the enzyme carboxypeptidase A.	got7fsn_ti	carboxypeptidase A inhibitor activity			GO:0030414	This term was made obsolete because it represents a regulator of an obsolete molecular function.					True				molecular_function											owl:Class	
GO:0016100	biolink:NamedThing	monoterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton.	got7fsn_ti	monoterpenoid degradation|monoterpenoid breakdown|monoterpenoid catabolism													biological_process											owl:Class	
GO:1902213	biolink:NamedThing	positive regulation of prolactin signaling pathway	Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.	got7fsn_ti	up-regulation of PRL signaling pathway|positive regulation of PRL signaling pathway|positive regulation of prolactin-mediated signaling pathway|upregulation of prolactin-mediated signaling pathway|up regulation of prolactin-mediated signaling pathway|up regulation of prolactin signaling pathway|up-regulation of prolactin-mediated signaling pathway|activation of prolactin signaling pathway|upregulation of prolactin signaling pathway|activation of PRL signaling pathway|up-regulation of prolactin signaling pathway|activation of prolactin-mediated signaling pathway|upregulation of PRL signaling pathway|up regulation of PRL signaling pathway						lb	2013-06-12T10:10:18Z						biological_process											owl:Class	
GO:0051491	biolink:NamedThing	positive regulation of filopodium assembly	Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.	got7fsn_ti	positive regulation of filopodia formation|up-regulation of filopodium formation|upregulation of filopodium formation|positive regulation of filopodia biosynthesis|stimulation of filopodium formation|up regulation of filopodium formation|positive regulation of filopodium formation|activation of filopodium formation													biological_process											owl:Class	
GO:0060754	biolink:NamedThing	positive regulation of mast cell chemotaxis	Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.	got7fsn_ti							dph	2009-06-22T02:38:19Z						biological_process											owl:Class	
GO:1902637	biolink:NamedThing	neural crest cell differentiation involved in thymus development	Any neural crest cell differentiation that is involved in thymus development.	got7fsn_ti							pr	2014-01-21T10:03:20Z						biological_process											owl:Class	
GO:0035020	biolink:NamedThing	regulation of Rac protein signal transduction	Any process that modulates the frequency, rate or extent of Rac protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:0030068	biolink:NamedThing	obsolete lytic viral life cycle	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lytic viral life cycle				This term was made obsolete because more specific terms were created.	GO:0044659|GO:0019058				True				biological_process											owl:Class	
GO:0061006	biolink:NamedThing	regulation of cell proliferation involved in kidney morphogenesis	Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.	got7fsn_ti							dph	2010-01-21T11:25:23Z						biological_process											owl:Class	
CHEBI:128769	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003966	biolink:NamedThing	obsolete RNA-directed DNA polymerase, transposon encoded	OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo.	got7fsn_ti	RNA-directed DNA polymerase, transposon encoded			GO:0003964	This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'.					True				molecular_function											owl:Class	
GO:1904138	biolink:NamedThing	positive regulation of convergent extension involved in notochord morphogenesis	Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis.	got7fsn_ti	activation of convergent extension involved in notochord morphogenesis|up-regulation of convergent extension involved in notochord morphogenesis|upregulation of convergent extension involved in notochord morphogenesis|up regulation of convergent extension involved in notochord morphogenesis						dph	2015-04-10T21:21:41Z						biological_process											owl:Class	
GO:0060357	biolink:NamedThing	regulation of leucine import	Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.	got7fsn_ti	regulation of L-leucine import|regulation of L-leucine uptake|regulation of leucine uptake													biological_process											owl:Class	
GO:1904919	biolink:NamedThing	transmembrane L-cystine transport from lysosomal lumen to cytosol	The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol.	got7fsn_ti							kmv	2016-01-21T16:28:02Z						biological_process											owl:Class	
GO:1903563	biolink:NamedThing	microtubule bundle formation involved in horsetail-astral microtubule organization	Any microtubule bundle formation that is involved in horsetail-astral microtubule organization.	got7fsn_ti	microtubule bundling involved in horsetail-astral microtubule organization|microtubule bundling involved in horsetail-astral microtubule array organization|microtubule bundle formation involved in horsetail-astral microtubule array organization|microtubule bundle formation involved in horsetail-astral microtubule organisation|microtubule bundling involved in horsetail-astral microtubule organisation						vw	2014-10-23T11:06:35Z						biological_process											owl:Class	
GO:1903585	biolink:NamedThing	negative regulation of histone deubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination.	got7fsn_ti	down regulation of histone deubiquitinylation|inhibition of histone deubiquitination|down-regulation of histone deubiquitylation|down-regulation of histone deubiquitination|inhibition of histone deubiquitylation|downregulation of histone deubiquitylation|downregulation of histone deubiquitinylation|downregulation of histone deubiquitination|down-regulation of histone deubiquitinylation|negative regulation of histone deubiquitinylation|negative regulation of histone deubiquitylation|down regulation of histone deubiquitination|inhibition of histone deubiquitinylation|down regulation of histone deubiquitylation						lb	2014-11-03T13:47:35Z						biological_process											owl:Class	
GO:1903886	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 20 production	Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.	got7fsn_ti	up regulation of CCL-20 production|activation of CCL-20 production|up regulation of C-C motif chemokine 20 production|positive regulation of CCL-20 production|activation of C-C motif chemokine 20 production|upregulation of CCL-20 production|upregulation of C-C motif chemokine 20 production|up-regulation of CCL20 production|positive regulation of CCL20 production|up-regulation of C-C motif chemokine 20 production|up-regulation of CCL-20 production|activation of chemokine (C-C motif) ligand 20 production|upregulation of chemokine (C-C motif) ligand 20 production|up regulation of CCL20 production|positive regulation of C-C motif chemokine 20 production|activation of CCL20 production|up-regulation of chemokine (C-C motif) ligand 20 production|up regulation of chemokine (C-C motif) ligand 20 production|upregulation of CCL20 production						krc	2015-02-06T16:31:20Z						biological_process											owl:Class	
GO:0140484	biolink:NamedThing	5-aminolevulinic acid import across plasma membrane	The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19527					pg	2020-06-29T08:59:24Z						biological_process											owl:Class	
GO:0046345	biolink:NamedThing	abscisic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.	got7fsn_ti	abscisic acid degradation|abscisic acid breakdown|abscisic acid catabolism													biological_process											owl:Class	
GO:1905953	biolink:NamedThing	negative regulation of lipid localization	Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.	got7fsn_ti	down-regulation of lipid localisation|negative regulation of lipid localisation|inhibition of lipid localization|down regulation of lipid localisation|downregulation of lipid localisation|inhibition of lipid localisation|down regulation of lipid localization|down-regulation of lipid localization|downregulation of lipid localization						rz	2017-02-21T12:12:41Z						biological_process											owl:Class	
GO:1900851	biolink:NamedThing	positive regulation of pseurotin A biosynthetic process	Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process.	got7fsn_ti	upregulation of pseurotin A biosynthetic process|up-regulation of pseurotin A biosynthetic process|up regulation of pseurotin A biosynthetic process						di	2012-06-07T09:45:56Z						biological_process											owl:Class	
GO:1905001	biolink:NamedThing	negative regulation of membrane repolarization during atrial cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.	got7fsn_ti	downregulation of membrane repolarization during atrial cardiac muscle cell action potential|downregulation of electrocardiogram QRS complex|down-regulation of electrocardiogram QRS complex|down-regulation of membrane repolarization during atrial cardiac muscle cell action potential|negative regulation of electrocardiogram QRS complex|inhibition of electrocardiogram QRS complex|down-regulation of atrial repolarization|negative regulation of atrial repolarization|inhibition of atrial repolarization|down regulation of membrane repolarization during atrial cardiac muscle cell action potential|down regulation of atrial repolarization|downregulation of atrial repolarization|down regulation of electrocardiogram QRS complex|inhibition of membrane repolarization during atrial cardiac muscle cell action potential						rph	2016-03-01T13:28:13Z						biological_process											owl:Class	
GO:0044113	biolink:NamedThing	obsolete development in other organism involved in symbiotic interaction	OBSOLETE. The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism.	got7fsn_ti	development in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/20305			This term was obsoleted because it represents both a process and a location.		jl	2009-07-30T02:32:38Z		True				biological_process											owl:Class	
GO:0031935	biolink:NamedThing	obsolete regulation of chromatin silencing	OBSOLETE. Any process that affects the rate, extent or location of chromatin silencing.	got7fsn_ti	regulation of heterochromatic silencing	https://github.com/geneontology/go-ontology/issues/22060			This term was obsoleted because it was too vague: regulation of chromatin (gene) silencing takes place via upstream signaling pathways.					True				biological_process											owl:Class	
GO:1900948	biolink:NamedThing	negative regulation of isoprene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process.	got7fsn_ti	down-regulation of hemiterpene biosynthesis|inhibition of 2-methyl-1,3-butadiene biosynthesis|inhibition of hemiterpene biosynthetic process|down regulation of hemiterpene biosynthesis|negative regulation of 2-methyl-1,3-butadiene biosynthesis|downregulation of hemiterpene biosynthesis|down regulation of hemiterpene biosynthetic process|negative regulation of 2-methyl-1,3-butadiene biosynthetic process|downregulation of 2-methyl-1,3-butadiene biosynthesis|down-regulation of isoprene biosynthetic process|down-regulation of 2-methyl-1,3-butadiene biosynthetic process|down regulation of 2-methyl-1,3-butadiene biosynthesis|inhibition of hemiterpene biosynthesis|down regulation of isoprene biosynthetic process|downregulation of isoprene biosynthetic process|downregulation of hemiterpene biosynthetic process|down-regulation of 2-methyl-1,3-butadiene biosynthesis|downregulation of 2-methyl-1,3-butadiene biosynthetic process|down-regulation of hemiterpene biosynthetic process|inhibition of isoprene biosynthetic process|down regulation of 2-methyl-1,3-butadiene biosynthetic process|inhibition of 2-methyl-1,3-butadiene biosynthetic process|negative regulation of hemiterpene biosynthetic process|negative regulation of hemiterpene biosynthesis						tt	2012-06-14T03:21:47Z						biological_process											owl:Class	
GO:1900075	biolink:NamedThing	positive regulation of neuromuscular synaptic transmission	Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.	got7fsn_ti	activation of neuromuscular synaptic transmission|up-regulation of neuromuscular synaptic transmission|upregulation of neuromuscular synaptic transmission|up regulation of neuromuscular synaptic transmission						kmv	2012-01-26T10:14:22Z						biological_process											owl:Class	
GO:0043267	biolink:NamedThing	negative regulation of potassium ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	down regulation of potassium ion transport|negative regulation of K+ transport|transmembrane conductance regulator activity|negative regulation of potassium ion conductance|regulation of K+ conductance|downregulation of potassium ion transport|down-regulation of potassium ion transport|inhibition of potassium ion transport|negative regulation of potassium transport|regulation of potassium conductance													biological_process											owl:Class	
GO:1903266	biolink:NamedThing	regulation of ornithine catabolic process	Any process that modulates the frequency, rate or extent of ornithine catabolic process.	got7fsn_ti	regulation of ornithine degradation|regulation of ornithine breakdown|regulation of ornithine catabolism				An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay).		bhm	2014-08-08T08:29:33Z						biological_process											owl:Class	
GO:0009197	biolink:NamedThing	pyrimidine deoxyribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside diphosphate synthesis|pyrimidine deoxyribonucleoside diphosphate formation|pyrimidine deoxyribonucleoside diphosphate anabolism|pyrimidine deoxyribonucleoside diphosphate biosynthesis													biological_process											owl:Class	
GO:0060759	biolink:NamedThing	regulation of response to cytokine stimulus	Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.	got7fsn_ti							dph	2009-06-22T02:56:12Z						biological_process											owl:Class	
GO:0070964	biolink:NamedThing	positive regulation of neutrophil mediated killing of gram-positive bacterium	Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.	got7fsn_ti	up-regulation of neutrophil mediated killing of gram-positive bacterium|activation of neutrophil mediated killing of gram-positive bacterium|stimulation of neutrophil mediated killing of gram-positive bacterium|upregulation of neutrophil mediated killing of gram-positive bacterium|up regulation of neutrophil mediated killing of gram-positive bacterium						mah	2009-10-01T02:28:49Z						biological_process											owl:Class	
GO:1903450	biolink:NamedThing	regulation of G1 to G0 transition	Any process that modulates the frequency, rate or extent of G1 to G0 transition.	got7fsn_ti	regulation of G1/G0 transition|regulation of stationary phase|regulation of cell cycle quiescence|regulation of establishment of cell quiescence						di	2014-09-19T22:23:13Z						biological_process											owl:Class	
PR:000002094	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900981	biolink:NamedThing	negative regulation of phenazine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process.	got7fsn_ti	down-regulation of dibenzopyrazine biosynthesis|down-regulation of acridizine biosynthetic process|inhibition of dibenzo-p-diazine biosynthesis|down regulation of dibenzo-p-diazine biosynthetic process|negative regulation of azophenylene biosynthetic process|inhibition of phenazine biosynthetic process|down-regulation of azophenylene biosynthesis|downregulation of phenazine biosynthetic process|down regulation of phenazine biosynthetic process|down-regulation of dibenzo-p-diazine biosynthetic process|down regulation of acridizine biosynthesis|downregulation of dibenzo-p-diazine biosynthesis|down-regulation of dibenzopyrazine biosynthetic process|down regulation of dibenzo-p-diazine biosynthesis|downregulation of acridizine biosynthesis|inhibition of dibenzopyrazine biosynthesis|downregulation of dibenzo-p-diazine biosynthetic process|down regulation of dibenzopyrazine biosynthesis|inhibition of acridizine biosynthetic process|downregulation of dibenzopyrazine biosynthetic process|negative regulation of dibenzopyrazine biosynthetic process|inhibition of dibenzo-p-diazine biosynthetic process|down-regulation of dibenzo-p-diazine biosynthesis|downregulation of acridizine biosynthetic process|down regulation of azophenylene biosynthetic process|down-regulation of phenazine biosynthetic process|inhibition of azophenylene biosynthesis|negative regulation of dibenzopyrazine biosynthesis|down regulation of azophenylene biosynthesis|negative regulation of dibenzo-p-diazine biosynthetic process|inhibition of azophenylene biosynthetic process|negative regulation of dibenzo-p-diazine biosynthesis|negative regulation of azophenylene biosynthesis|down-regulation of azophenylene biosynthetic process|inhibition of dibenzopyrazine biosynthetic process|down regulation of dibenzopyrazine biosynthetic process|downregulation of azophenylene biosynthetic process|downregulation of dibenzopyrazine biosynthesis|downregulation of azophenylene biosynthesis|down-regulation of acridizine biosynthesis|down regulation of acridizine biosynthetic process|negative regulation of acridizine biosynthesis|inhibition of acridizine biosynthesis|negative regulation of acridizine biosynthetic process						tt	2012-06-14T04:05:03Z						biological_process											owl:Class	
GO:1900951	biolink:NamedThing	negative regulation of 18-methylnonadec-1-ene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.	got7fsn_ti	down regulation of 18-methylnonadec-1-ene biosynthetic process|down-regulation of 18-methylnonadec-1-ene formation|negative regulation of 18-methylnonadec-1-ene synthesis|downregulation of 18-methylnonadec-1-ene synthesis|downregulation of 18-methylnonadec-1-ene formation|negative regulation of 18-methylnonadec-1-ene formation|negative regulation of 18-methylnonadec-1-ene anabolism|inhibition of 18-methylnonadec-1-ene biosynthesis|downregulation of 18-methylnonadec-1-ene biosynthesis|down regulation of 18-methylnonadec-1-ene anabolism|inhibition of 18-methylnonadec-1-ene synthesis|down regulation of 18-methylnonadec-1-ene synthesis|down-regulation of 18-methylnonadec-1-ene biosynthesis|negative regulation of 18-methylnonadec-1-ene biosynthesis|down-regulation of 18-methylnonadec-1-ene synthesis|inhibition of 18-methylnonadec-1-ene formation|inhibition of 18-methylnonadec-1-ene anabolism|down regulation of 18-methylnonadec-1-ene biosynthesis|down-regulation of 18-methylnonadec-1-ene anabolism|down-regulation of 18-methylnonadec-1-ene biosynthetic process|downregulation of 18-methylnonadec-1-ene biosynthetic process|down regulation of 18-methylnonadec-1-ene formation|downregulation of 18-methylnonadec-1-ene anabolism|inhibition of 18-methylnonadec-1-ene biosynthetic process						tt	2012-06-14T03:23:55Z						biological_process											owl:Class	
GO:0052366	biolink:NamedThing	obsolete catabolism by organism of xylan in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism by organism of xylan in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0039543	biolink:NamedThing	obsolete suppression by virus of host RIG-I activity by viral RNA 5' processing	OBSOLETE. The post-transcriptional removal by a virus of the 5' triphosphate group of their viral RNA, thereby preventing host RIG-I from recognizing viral RNA in the host cell. The intracellular pattern recognition receptor RIG-I (also known as DDX58) recognizes viral RNAs containing 5' triphosphates; removal by the virus of the 5'-terminal triphosphate group from their genome protects the viral RNA from RIG-recognition.	got7fsn_ti	suppression by virus of host RIG-I activity by inhibition of RNA binding				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-18T02:30:29Z		True				biological_process											owl:Class	
GO:1903554	biolink:NamedThing	G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium	Any G protein-coupled receptor signaling pathway that is involved in defense response to Gram-negative bacterium.	got7fsn_ti	G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacterium|G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria|GPCR signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor signaling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in defense response to Gram-negative bacteria|GPCR signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacteria|G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacterium|G-protein-coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity|GPCR signaling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|GPCR signaling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacteria|GPCR signalling pathway involved in defense response to Gram-negative bacterium|GPCR signalling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria|GPCR signalling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in defence response to Gram-negative bacterium|G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G-protein-coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor signalling pathway involved in Gram-negative antibacterial peptide activity|GPCR signaling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria						kmv	2014-10-20T17:51:13Z						biological_process											owl:Class	
GO:0072368	biolink:NamedThing	obsolete regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of lipid transport by negative regulation of transcription from an RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:18:13Z		True				biological_process											owl:Class	
GO:0051336	biolink:NamedThing	regulation of hydrolase activity	Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.	got7fsn_ti	hydrolase regulator													biological_process											owl:Class	
GO:1905559	biolink:NamedThing	positive regulation of mitotic nuclear envelope disassembly	Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.	got7fsn_ti	up-regulation of mitotic nuclear envelope catabolism|activation of mitotic nuclear envelope disassembly|up-regulation of mitotic nuclear envelope breakdown|positive regulation of mitotic nuclear envelope catabolism|upregulation of mitotic nuclear envelope disassembly|up-regulation of mitotic nuclear envelope degradation|up regulation of mitotic nuclear envelope breakdown|up regulation of mitotic nuclear envelope catabolism|activation of mitotic nuclear envelope breakdown|positive regulation of mitotic nuclear envelope degradation|upregulation of mitotic nuclear envelope degradation|up regulation of mitotic nuclear envelope disassembly|activation of mitotic nuclear envelope catabolism|positive regulation of mitotic nuclear envelope breakdown|upregulation of mitotic nuclear envelope catabolism|activation of mitotic nuclear envelope degradation|up-regulation of mitotic nuclear envelope disassembly|up regulation of mitotic nuclear envelope degradation|upregulation of mitotic nuclear envelope breakdown						hbye	2016-10-14T13:15:17Z						biological_process											owl:Class	
GO:0009964	biolink:NamedThing	negative regulation of flavonoid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.	got7fsn_ti	downregulation of flavonoid biosynthetic process|negative regulation of flavonoid biosynthesis|negative regulation of flavonoid formation|negative regulation of flavonoid anabolism|negative regulation of flavonoid synthesis|down regulation of flavonoid biosynthetic process|inhibition of flavonoid biosynthetic process|down-regulation of flavonoid biosynthetic process													biological_process											owl:Class	
GO:2000450	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta T cell extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.	got7fsn_ti							bf	2011-03-04T10:41:43Z						biological_process											owl:Class	
GO:0071931	biolink:NamedThing	positive regulation of transcription involved in G1/S transition of mitotic cell cycle	Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle						mah	2010-09-29T11:15:34Z						biological_process											owl:Class	
GO:0003734	biolink:NamedThing	obsolete small nuclear ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	small nuclear ribonucleoprotein|snRNP			GO:0030532	This term was made obsolete because it describes a cellular component rather than a molecular function.					True				molecular_function											owl:Class	
GO:2000518	biolink:NamedThing	negative regulation of T-helper 1 cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation.	got7fsn_ti	negative regulation of Th1 cell activation						ebc	2011-03-22T10:40:26Z						biological_process											owl:Class	
GO:1902553	biolink:NamedThing	positive regulation of catalase activity	Any process that activates or increases the frequency, rate or extent of catalase activity.	got7fsn_ti	upregulation of haem catalase activity|positive regulation of heme catalase activity|up regulation of catalase-peroxidase activity|upregulation of manganese catalase activity|activation of bacterial catalase-peroxidase activity|upregulation of optidase activity|up-regulation of caperase activity|up regulation of equilase activity|activation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|up regulation of haem catalase activity|activation of caperase activity|up-regulation of manganese catalase activity|activation of haem catalase activity|upregulation of bacterial catalase-peroxidase activity|positive regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|activation of heme catalase activity|up-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|upregulation of catalase-peroxidase activity|up-regulation of heme catalase activity|up-regulation of CAT|up-regulation of catalase-peroxidase activity|positive regulation of manganese catalase activity|positive regulation of CAT|positive regulation of optidase activity|positive regulation of bacterial catalase-peroxidase activity|positive regulation of equilase activity|upregulation of caperase activity|activation of equilase activity|activation of catalase activity|up-regulation of equilase activity|up regulation of CAT|up regulation of caperase activity|upregulation of heme catalase activity|up regulation of bacterial catalase-peroxidase activity|up regulation of optidase activity|activation of manganese catalase activity|upregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|up regulation of catalase activity|activation of optidase activity|upregulation of equilase activity|up-regulation of catalase activity|up regulation of manganese catalase activity|activation of catalase-peroxidase activity|positive regulation of catalase reaction|positive regulation of caperase activity|up-regulation of bacterial catalase-peroxidase activity|up-regulation of optidase activity|positive regulation of haem catalase activity|positive regulation of catalase-peroxidase activity|up-regulation of catalase reaction|up regulation of catalase reaction|activation of CAT|up regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|upregulation of catalase activity|up regulation of heme catalase activity|activation of catalase reaction|upregulation of CAT|upregulation of catalase reaction|up-regulation of haem catalase activity						tb	2013-12-04T21:56:03Z						biological_process											owl:Class	
GO:0038082	biolink:NamedThing	obsolete MAP kinase phosphatase activity involved in regulation of osmosensory signaling pathway	OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.	got7fsn_ti	MAPK phosphatase activity involved in regulation of osmosensory signaling pathway|MAP kinase phosphatase activity involved in regulation of osmosensory signalling pathway|Hog1 phosphatase activity				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:41:31Z		True				molecular_function											owl:Class	
GO:0051848	biolink:NamedThing	obsolete active evasion of symbiont immune response via regulation of symbiont cytokine network	OBSOLETE. Any mechanism of active immune avoidance which works by regulating symbiont cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester symbiont cytokines and inhibit action. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	active immune evasion via regulation of symbiont cytokine network|active evasion of symbiont immune response via regulation of symbiont cytokine network|active immune evasion via modulation of symbiont cytokine network				This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
GO:0004864	biolink:NamedThing	protein phosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.	got7fsn_ti	protein phosphatase type 2A inhibitor activity|phosphoprotein phosphatase inhibitor activity|protein phosphatase 2 inhibitor activity						rb	2015-03-03T23:57:25Z			GO:1990681			molecular_function											owl:Class	
GO:1904091	biolink:NamedThing	peptidyl carrier protein activity	Binding an amino-acid derived peptidyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the peptidyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. Peptidyl carrier protein (PCP) is involved in nonribosomal peptide biosynthetic process.	got7fsn_ti	oligopeptides binding involved in nonribosomal peptide biosynthetic process|peptidyl binding involved in nonribosomal peptide biosynthesis|PCP|oligopeptide binding involved in non-ribosomal peptide formation|oligopeptides binding involved in non-ribosomal peptide biosynthesis|oligopeptido binding involved in non-ribosomal peptide biosynthesis|Oligopeptid binding involved in nonribosomal peptide synthesis|Oligopeptid binding involved in non-ribosomal peptide synthesis|peptidyl binding involved in nonribosomal peptide biosynthetic process|oligopeptido binding involved in non-ribosomal peptide synthesis|oligopeptides binding involved in nonribosomal peptide biosynthesis|oligopeptide binding involved in non-ribosomal peptide synthesis|Oligopeptid binding involved in non-ribosomal peptide formation|oligopeptides binding involved in non-ribosomal peptide biosynthetic process|Oligopeptid binding involved in nonribosomal peptide anabolism|oligopeptido binding involved in nonribosomal peptide synthesis|oligopeptide binding involved in nonribosomal peptide biosynthesis|oligopeptido binding involved in non-ribosomal peptide biosynthetic process|oligopeptides binding involved in nonribosomal peptide synthesis|Oligopeptid binding involved in nonribosomal peptide biosynthesis|oligopeptides binding involved in nonribosomal peptide synthetase|oligopeptides binding involved in nonribosomal peptide formation|oligopeptido binding involved in nonribosomal peptide biosynthetic process|Oligopeptid binding involved in non-ribosomal peptide biosynthesis|oligopeptido binding involved in nonribosomal peptide anabolism|oligopeptide binding involved in nonribosomal peptide synthetase|Oligopeptid binding involved in nonribosomal peptide synthetase|peptidyl carrier protein|oligopeptide binding involved in nonribosomal peptide formation|Oligopeptid binding involved in nonribosomal peptide biosynthetic process|peptidyl carrier protein activity involved in nonribosomal peptide biosynthetic process|oligopeptide binding involved in non-ribosomal peptide biosynthesis|peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis|oligopeptide binding involved in nonribosomal peptide biosynthetic process|oligopeptide binding involved in non-ribosomal peptide biosynthetic process|Oligopeptid binding involved in non-ribosomal peptide biosynthetic process|oligopeptides binding involved in non-ribosomal peptide formation|oligopeptido binding involved in nonribosomal peptide synthetase|oligopeptides binding involved in non-ribosomal peptide synthesis|oligopeptido binding involved in nonribosomal peptide formation|oligopeptide binding involved in nonribosomal peptide synthesis|Oligopeptid binding involved in nonribosomal peptide formation|oligopeptide binding involved in nonribosomal peptide anabolism|oligopeptides binding involved in nonribosomal peptide anabolism|oligopeptido binding involved in nonribosomal peptide biosynthesis|oligopeptido binding involved in non-ribosomal peptide formation				Examples are the ferrichrome synthetase Sib1 in S. pombe and the peptidyl carrier protein (PCP) module in bacterial nonribosomal peptide synthases (NRPSs), which holds the peptidyl group and acts as a swinging arm, limiting diffusion until the peptide comes into contact with the next enzymatic module in the NRPS process.		pr	2015-03-26T10:41:52Z						molecular_function											owl:Class	
GO:0030006	biolink:NamedThing	obsolete heavy cellular metal ion homeostasis	OBSOLETE. Regulation of the levels, transport, and metabolism of ions of a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	got7fsn_ti	heavy cellular metal ion homeostasis				This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0006875				True				biological_process											owl:Class	
GO:0007125	biolink:NamedThing	obsolete invasive growth	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	invasive growth				This term was made obsolete because it has been split into two new terms.	GO:0044409|GO:0001403				True				biological_process											owl:Class	
GO:1904471	biolink:NamedThing	negative regulation of endothelin production	Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production.	got7fsn_ti	negative regulation of EDN2 secretion|inhibition of EDN3 secretion|negative regulation of endothelin-3 secretion|inhibition of endothelin secretion|downregulation of EDN2 secretion|negative regulation of endothelin-1 secretion|down-regulation of EDN1 secretion|down regulation of EDN1 secretion|downregulation of EDN1 secretion|negative regulation of endothelin-2 secretion|downregulation of endothelin secretion|down regulation of endothelin-2 secretion|down regulation of endothelin-1 secretion|down-regulation of endothelin-1 secretion|negative regulation of EDN3 secretion|down regulation of endothelin-3 secretion|down-regulation of endothelin-2 secretion|down regulation of endothelin secretion|down-regulation of endothelin-3 secretion|down-regulation of EDN3 secretion|down regulation of EDN2 secretion|inhibition of endothelin-2 secretion|down regulation of EDN3 secretion|downregulation of EDN3 secretion|downregulation of endothelin-1 secretion|down-regulation of EDN2 secretion|inhibition of EDN2 secretion|downregulation of endothelin-3 secretion|negative regulation of EDN1 secretion|down-regulation of endothelin secretion|negative regulation of endothelin secretion|inhibition of EDN1 secretion|inhibition of endothelin-3 secretion|inhibition of endothelin-1 secretion|downregulation of endothelin-2 secretion						sl	2015-07-09T19:58:03Z						biological_process											owl:Class	
GO:1903392	biolink:NamedThing	negative regulation of adherens junction organization	Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization.	got7fsn_ti	downregulation of adherens junction organization|negative regulation of adherens junction organisation|downregulation of adherens junction organisation|down-regulation of adherens junction organization|down-regulation of adherens junction organisation|inhibition of adherens junction organisation|downregulation of adherens junction assembly and maintenance|down regulation of adherens junction organization|negative regulation of adherens junction assembly and maintenance|down regulation of adherens junction assembly and maintenance|down regulation of adherens junction organisation|down-regulation of adherens junction assembly and maintenance|inhibition of adherens junction organization|inhibition of adherens junction assembly and maintenance						als	2014-08-27T10:08:47Z						biological_process											owl:Class	
GO:0061188	biolink:NamedThing	negative regulation of ribosomal DNA heterochromatin assembly	Any process that decreases the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin.	got7fsn_ti	negative regulation of chromatin silencing at rDNA	https://github.com/geneontology/go-ontology/issues/19238					dph	2010-07-14T09:07:59Z						biological_process											owl:Class	
GO:0070438	biolink:NamedThing	obsolete mTOR-FKBP12-rapamycin complex	OBSOLETE. A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus).	got7fsn_ti	Fkbp1a-Frap1 complex|mTOR-FKBP12-rapamycin complex				This term was made obsolete because it describes a complex with a drug bound, with the drug being exogenous to the species where the experiment takes place and where that interaction would never occur naturally.					True				cellular_component											owl:Class	
GO:1903783	biolink:NamedThing	negative regulation of sodium ion import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane.	got7fsn_ti	inhibition of sodium ion import across plasma membrane|downregulation of sodium ion import across plasma membrane|down regulation of sodium ion import across plasma membrane|down-regulation of sodium ion import across plasma membrane						nc	2015-01-07T16:48:51Z						biological_process											owl:Class	
GO:0106057	biolink:NamedThing	negative regulation of calcineurin-mediated signaling	Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signalling.	got7fsn_ti							hjd	2017-09-18T16:50:11Z						biological_process											owl:Class	
GO:0043275	biolink:NamedThing	obsolete glutamate carboxypeptidase II activity	OBSOLETE. Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu.	got7fsn_ti	pteroylpolygammaglutamyl hydrolase activity|folate hydrolase activity|N-acetylated-gamma-linked-acidic dipeptidase activity|glutamate carboxypeptidase II activity|microsomal gamma-glutamyl carboxypeptidase|pteroylpolyglutamic acid hydrolase activity|NAALADase activity|N-acetylated-gamma-linked-acidic dipeptidase (NAALADase)|membrane glutamate carboxypeptidase|folylpolyglutamate hydrolase activity|NAALA dipeptidase activity|PSMA|pteroylpoly-gamma-glutamate carboxypeptidase activity|rat NAAG peptidase|prostrate-specific membrane antigen|mGCP|pteroylpoly-gamma-glutamate hydrolase activity|N-acetylated-alpha-linked-amino dipeptidase activity|N-acetylated alpha-linked acidic dipeptidase activity|prostate-specific membrane antigen|acetylaspartylglutamate dipeptidase activity|pteroylpolyglutamate hydrolase activity|PSM antigen			GO:0004181	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0042361	biolink:NamedThing	menaquinone catabolic process	The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.	got7fsn_ti	menaquinone breakdown|menatetrenone catabolism|vitamin K2 catabolic process|menaquinone degradation|menaquinone catabolism|multiprenylmenaquinone catabolic process|menatetrenone catabolic process|vitamin K2 catabolism|multiprenylmenaquinone catabolism													biological_process											owl:Class	
GO:2000208	biolink:NamedThing	positive regulation of ribosomal small subunit export from nucleus	Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus.	got7fsn_ti	positive regulation of ribosomal small subunit-nucleus export|positive regulation of ribosomal small subunit transport from nucleus to cytoplasm|positive regulation of ribosomal small subunit export out of nucleus|positive regulation of ribosomal small subunit export from cell nucleus|positive regulation of 30S ribosomal subunit export from nucleus|positive regulation of 40S ribosomal subunit export from nucleus						mah	2010-10-26T10:54:16Z						biological_process											owl:Class	
GO:1904293	biolink:NamedThing	negative regulation of ERAD pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway.	got7fsn_ti	downregulation of endoplasmic reticulum-associated protein degradation pathway|downregulation of endoplasmic reticulum-associated degradation|down regulation of endoplasmic reticulum-associated degradation|negative regulation of endoplasmic reticulum-associated degradation|inhibition of ERAD pathway|downregulation of ERAD pathway|down-regulation of ER-associated degradation pathway|down-regulation of endoplasmic reticulum-associated degradation|down-regulation of endoplasmic reticulum-associated protein degradation pathway|negative regulation of endoplasmic reticulum-associated protein degradation pathway|down-regulation of ERAD pathway|negative regulation of ER-associated degradation pathway|down regulation of endoplasmic reticulum-associated protein degradation pathway|inhibition of endoplasmic reticulum-associated degradation|downregulation of ER-associated degradation pathway|inhibition of ER-associated degradation pathway|down regulation of ER-associated degradation pathway|down regulation of ERAD pathway|inhibition of endoplasmic reticulum-associated protein degradation pathway						bf	2015-06-09T14:44:33Z						biological_process											owl:Class	
GO:0051137	biolink:NamedThing	negative regulation of NK T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.	got7fsn_ti	negative regulation of natural T cell differentiation|negative regulation of NK T-lymphocyte differentiation|downregulation of NK T cell differentiation|negative regulation of NK T-cell differentiation|inhibition of NK T cell differentiation|negative regulation of NK T lymphocyte differentiation|negative regulation of natural killer T cell differentiation|negative regulation of NK T cell development|negative regulation of NT cell differentiation|down regulation of NK T cell differentiation|down-regulation of NK T cell differentiation|negative regulation of NKT cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0140052	biolink:NamedThing	cellular response to oxidised low-density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus.	got7fsn_ti	cellular response to oxidized low-density lipoprotein particle stimulus|cellular response to oxidized LDL particle stimulus|cellular response to oxLDL particle stimulus|cellular response to ox-LDL particle stimulus|cellular response to oxidised LDL particle stimulus						pg	2017-06-26T09:40:00Z						biological_process											owl:Class	
GO:2000674	biolink:NamedThing	regulation of type B pancreatic cell apoptotic process	Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process.	got7fsn_ti	regulation of type B pancreatic cell apoptosis|regulation of pancreatic B cell apoptosis|regulation of pancreatic beta cell apoptosis						pr	2011-05-09T11:51:09Z						biological_process											owl:Class	
GO:0033044	biolink:NamedThing	regulation of chromosome organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.	got7fsn_ti	regulation of chromosome organisation|regulation of chromosome organization and biogenesis													biological_process											owl:Class	
GO:0072361	biolink:NamedThing	obsolete regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T02:57:18Z		True				biological_process											owl:Class	
GO:1904247	biolink:NamedThing	positive regulation of polynucleotide adenylyltransferase activity	Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.	got7fsn_ti	up-regulation of ATP:polynucleotide adenylyltransferase activity|up-regulation of polyadenylate synthetase activity|up regulation of polyadenylate polymerase activity|upregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|positive regulation of ATP-polynucleotide adenylyltransferase activity|up-regulation of RNA formation factors, PF1|activation of RNA adenylating enzyme activity|positive regulation of polyadenylate polymerase activity|activation of polyadenylic acid polymerase activity|up-regulation of poly(A) synthetase activity|positive regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|upregulation of NTP polymerase activity|up-regulation of polyadenylic polymerase activity|upregulation of poly(A) synthetase activity|up regulation of NTP polymerase activity|up-regulation of ATP:polynucleotidylexotransferase activity|up regulation of poly(A) polymerase activity|up-regulation of poly-A polymerase activity|up-regulation of AMP polynucleotidylexotransferase activity|up-regulation of polyadenylic acid polymerase activity|upregulation of ATP-polynucleotide adenylyltransferase activity|up-regulation of RNA adenylating enzyme activity|up regulation of ATP:polynucleotidylexotransferase activity|upregulation of polyadenylate polymerase activity|up regulation of polynucleotide adenylyltransferase activity|activation of polyadenylate polymerase activity|up-regulation of NTP polymerase activity|up-regulation of terminal riboadenylate transferase activity|up regulation of poly(A) synthetase activity|activation of polynucleotide adenylyltransferase activity|up-regulation of polyadenylate polymerase activity|activation of poly(A) synthetase activity|positive regulation of poly(A) hydrolase activity|up regulation of RNA adenylating enzyme activity|up-regulation of poly(A) hydrolase activity|positive regulation of poly(A) synthetase activity|activation of ATP:polynucleotidylexotransferase activity|up-regulation of poly(A) polymerase activity|upregulation of RNA formation factors, PF1|positive regulation of polyadenylic acid polymerase activity|activation of AMP polynucleotidylexotransferase activity|positive regulation of RNA adenylating enzyme activity|upregulation of ATP:polynucleotide adenylyltransferase activity|up-regulation of polyadenylate nucleotidyltransferase activity|up regulation of polyadenylate synthetase activity|upregulation of RNA adenylating enzyme activity|positive regulation of polyadenylate synthetase activity|up regulation of ATP-polynucleotide adenylyltransferase activity|up regulation of AMP polynucleotidylexotransferase activity|activation of polyadenylate nucleotidyltransferase activity|activation of polyadenylic polymerase activity|activation of ATP:polynucleotide adenylyltransferase activity|activation of polyadenylate synthetase activity|positive regulation of terminal riboadenylate transferase activity|activation of terminal riboadenylate transferase activity|up regulation of polyadenylic acid polymerase activity|upregulation of ATP:polynucleotidylexotransferase activity|up regulation of poly(A) hydrolase activity|positive regulation of poly-A polymerase activity|up regulation of polyadenylic polymerase activity|positive regulation of NTP polymerase activity|up regulation of ATP:polynucleotide adenylyltransferase activity|up regulation of polyadenylate nucleotidyltransferase activity|positive regulation of AMP polynucleotidylexotransferase activity|up-regulation of polynucleotide adenylyltransferase activity|activation of ATP-polynucleotide adenylyltransferase activity|upregulation of terminal riboadenylate transferase activity|upregulation of poly(A) hydrolase activity|upregulation of poly-A polymerase activity|positive regulation of poly(A) polymerase activity|positive regulation of RNA formation factors, PF1|up-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|activation of poly(A) polymerase activity|activation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|positive regulation of polyadenylate nucleotidyltransferase activity|positive regulation of ATP:polynucleotidylexotransferase activity|upregulation of polyadenylic polymerase activity|up regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|activation of RNA formation factors, PF1|up regulation of terminal riboadenylate transferase activity|upregulation of polyadenylate nucleotidyltransferase activity|upregulation of polyadenylic acid polymerase activity|upregulation of AMP polynucleotidylexotransferase activity|positive regulation of polyadenylic polymerase activity|positive regulation of ATP:polynucleotide adenylyltransferase activity|activation of poly-A polymerase activity|upregulation of polynucleotide adenylyltransferase activity|upregulation of polyadenylate synthetase activity|up regulation of poly-A polymerase activity|up regulation of RNA formation factors, PF1|upregulation of poly(A) polymerase activity|activation of NTP polymerase activity|up-regulation of ATP-polynucleotide adenylyltransferase activity|activation of poly(A) hydrolase activity						kmv	2015-05-19T14:47:32Z						biological_process											owl:Class	
GO:1900090	biolink:NamedThing	positive regulation of inositol biosynthetic process	Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process.	got7fsn_ti	up regulation of inositol formation|upregulation of inositol formation|upregulation of inositol anabolism|up regulation of myo-inositol biosynthesis|activation of vitamin Bh biosynthetic process|up-regulation of inositol formation|upregulation of inositol biosynthetic process|up regulation of inositol biosynthesis|up-regulation of myo-inositol biosynthetic process|up-regulation of vitamin Bh biosynthetic process|activation of myo-inositol biosynthetic process|upregulation of vitamin Bh biosynthesis|upregulation of inositol biosynthesis|activation of inositol anabolism|up regulation of vitamin Bh biosynthesis|up-regulation of vitamin Bh biosynthesis|upregulation of inositol synthesis|up-regulation of inositol synthesis|up regulation of inositol synthesis|upregulation of myo-inositol biosynthesis|up regulation of inositol biosynthetic process|positive regulation of inositol formation|up-regulation of myo-inositol biosynthesis|up regulation of myo-inositol biosynthetic process|upregulation of myo-inositol biosynthetic process|positive regulation of inositol synthesis|activation of inositol formation|activation of myo-inositol biosynthesis|up regulation of vitamin Bh biosynthetic process|upregulation of vitamin Bh biosynthetic process|up-regulation of inositol biosynthesis|activation of inositol biosynthesis|up regulation of inositol anabolism|activation of inositol synthesis|positive regulation of vitamin Bh biosynthetic process|positive regulation of inositol biosynthesis|up-regulation of inositol anabolism|up-regulation of inositol biosynthetic process|positive regulation of vitamin Bh biosynthesis|positive regulation of myo-inositol biosynthesis|activation of inositol biosynthetic process|positive regulation of myo-inositol biosynthetic process|activation of vitamin Bh biosynthesis|positive regulation of inositol anabolism						dhl	2012-02-08T06:27:31Z						biological_process											owl:Class	
GO:0052512	biolink:NamedThing	obsolete positive regulation by organism of hormone or growth regulator levels in symbiont	OBSOLETE. The increase by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive modulation of hormone or growth regulator levels in symbiont|positive regulation by organism of hormone or growth regulator levels in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1904966	biolink:NamedThing	positive regulation of vitamin E biosynthetic process	Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.	got7fsn_ti	activation of alpha-tocopherol biosynthetic process|up-regulation of vitamin E biosynthesis|activation of vitamin E biosynthetic process|positive regulation of vitamin E anabolism|upregulation of vitamin E biosynthetic process|up-regulation of vitamin E formation|positive regulation of tocopherol biosynthesis|up regulation of vitamin E anabolism|upregulation of tocopherol biosynthesis|upregulation of vitamin E synthesis|activation of vitamin E biosynthesis|up regulation of vitamin E formation|up regulation of vitamin E biosynthetic process|up regulation of alpha-tocopherol biosynthetic process|up-regulation of tocopherol biosynthesis|upregulation of alpha-tocopherol biosynthesis|up regulation of tocopherol biosynthetic process|up-regulation of vitamin E synthesis|positive regulation of alpha-tocopherol biosynthesis|up-regulation of vitamin E anabolism|up regulation of tocopherol biosynthesis|up regulation of alpha-tocopherol biosynthesis|up regulation of vitamin E biosynthesis|activation of alpha-tocopherol biosynthesis|upregulation of vitamin E formation|activation of vitamin E synthesis|positive regulation of alpha-tocopherol biosynthetic process|activation of tocopherol biosynthesis|up-regulation of tocopherol biosynthetic process|up-regulation of vitamin E biosynthetic process|positive regulation of vitamin E biosynthesis|up regulation of vitamin E synthesis|upregulation of vitamin E anabolism|upregulation of tocopherol biosynthetic process|up-regulation of alpha-tocopherol biosynthesis|activation of tocopherol biosynthetic process|positive regulation of vitamin E synthesis|upregulation of alpha-tocopherol biosynthetic process|activation of vitamin E anabolism|up-regulation of alpha-tocopherol biosynthetic process|positive regulation of tocopherol biosynthetic process|upregulation of vitamin E biosynthesis|positive regulation of vitamin E formation|activation of vitamin E formation						tb	2016-02-12T17:57:03Z						biological_process											owl:Class	
GO:0009709	biolink:NamedThing	terpenoid indole alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).	got7fsn_ti	terpenoid indole alkaloid formation|terpenoid indole alkaloid biosynthesis|terpenoid indole alkaloid synthesis|terpenoid indole alkaloid anabolism													biological_process											owl:Class	
GO:0052525	biolink:NamedThing	obsolete positive regulation by host of symbiont signal transduction pathway	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	stimulation by host of symbiont signal transduction pathway|activation by host of symbiont signal transduction pathway|up regulation by host of symbiont signal transduction pathway|upregulation by host of symbiont signal transduction pathway|up-regulation by host of symbiont signal transduction pathway				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0001062	biolink:NamedThing	obsolete plastid PEP-A RNA polymerase activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-A RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16738		GO:0003899	This term was obsoleted because the activity is the same as its parent.		krc	2010-10-19T03:38:49Z		True				molecular_function											owl:Class	
GO:1903995	biolink:NamedThing	regulation of non-membrane spanning protein tyrosine kinase activity	Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.	got7fsn_ti	regulation of focal adhesion kinase activity|regulation of janus kinase 1 activity|regulation of cytoplasmic protein tyrosine kinase activity|regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|regulation of ATP:protein-tyrosine O-phosphotransferase activity|regulation of janus kinase 2 activity|regulation of janus kinase 3 activity|regulation of non-specific protein-tyrosine kinase activity|regulation of p60c-src protein tyrosine kinase activity|regulation of Bruton's tyrosine kinase activity						nc	2015-03-05T16:34:35Z						biological_process											owl:Class	
GO:1905356	biolink:NamedThing	regulation of snRNA pseudouridine synthesis	Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis.	got7fsn_ti							se	2016-08-09T19:12:27Z						biological_process											owl:Class	
GO:0007071	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle.	got7fsn_ti	downregulation of transcription from RNA polymerase III promoter during mitosis|down regulation of transcription from RNA polymerase III promoter during mitosis|negative regulation of transcription from RNA polymerase III promoter, mitotic|negative regulation of transcription from Pol III promoter during mitosis|mitotic repression of transcription from Pol III promoter|down-regulation of transcription from RNA polymerase III promoter during mitosis|inhibition of transcription from RNA polymerase III promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0016480				True				biological_process											owl:Class	
GO:1901012	biolink:NamedThing	(S)-reticuline biosynthetic process	The chemical reactions and pathways resulting in the formation of (S)-reticuline.	got7fsn_ti	(S)-reticuline formation|(S)-reticuline biosynthesis|(S)-reticuline anabolism|(S)-reticuline synthesis						yaf	2012-06-15T10:46:52Z						biological_process											owl:Class	
GO:1990271	biolink:NamedThing	obsolete anti-Mullerian hormone	OBSOLETE. Combining with anti-Mullerian hormone to initiate a change in cell activity.	got7fsn_ti	anti-Mullerian hormone				An example of this is Amdh2 in M. musculus, UniprotKB:Q8K592-1 in PMID:23624077.		hjd	2014-01-14T20:38:39Z		True				molecular_function											owl:Class	
GO:2000899	biolink:NamedThing	xyloglucan catabolic process	The chemical reactions and pathways resulting in the breakdown of a xyloglucan.	got7fsn_ti	xyloglucan catabolism						jl	2011-07-28T02:52:33Z						biological_process											owl:Class	
GO:0010021	biolink:NamedThing	amylopectin biosynthetic process	The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.	got7fsn_ti	amylopectin formation|amylopectin biosynthesis|amylopectin synthesis|amylopectin anabolism													biological_process											owl:Class	
GO:1990701	biolink:NamedThing	integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The component of the ERGIC membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral component of endoplasmic reticulum-Golgi intermediate compartment membrane|integral component of ER-Golgi intermediate compartment membrane|integral component of ERGIC membrane						bhm	2015-03-16T15:57:36Z						cellular_component											owl:Class	
GO:1902497	biolink:NamedThing	iron-sulfur cluster transmembrane transport	A process in which an iron-sulfur cluster is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	iron-sulfur cluster transport						dph	2013-11-13T16:33:00Z						biological_process											owl:Class	
GO:0006483	biolink:NamedThing	obsolete peptidyl-aspartic acid/asparagine hydroxylation	OBSOLETE. The hydroxylation of peptidyl-aspartic acid or asparagine.	got7fsn_ti	aspartic acid/asparagine hydroxylation|peptidyl-aspartic acid/asparagine hydroxylation				This term was made obsolete because it is a redundant grouping term.	GO:0042265|GO:0042264				True				biological_process											owl:Class	
GO:1902687	biolink:NamedThing	glucosidase complex	A protein complex which is capable of glucosidase activity.	got7fsn_ti					An example of this is ygjK in E. coli (P42592) in PMID:23826932.		bhm	2014-02-12T10:55:10Z						cellular_component											owl:Class	
GO:1903570	biolink:NamedThing	regulation of protein kinase D signaling	Any process that modulates the frequency, rate or extent of protein kinase D signaling.	got7fsn_ti	regulation of protein kinase D signaling cascade|regulation of protein kinase D signal transduction|regulation of PKD signaling cascade|regulation of protein kinase D signalling cascade|regulation of PKD signal transduction						rl	2014-10-27T15:18:00Z						biological_process											owl:Class	
GO:1904299	biolink:NamedThing	negative regulation of transcytosis	Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis.	got7fsn_ti	downregulation of transcytosis|inhibition of transcytosis|down-regulation of transcytosis|down regulation of transcytosis						sl	2015-06-09T22:53:32Z						biological_process											owl:Class	
GO:1905664	biolink:NamedThing	regulation of calcium ion import across plasma membrane	Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.	got7fsn_ti					An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay).		bhm	2016-11-11T09:26:06Z						biological_process											owl:Class	
GO:1903512	biolink:NamedThing	phytanic acid metabolic process	The chemical reactions and pathways involving phytanic acid.	got7fsn_ti	phytanic acid metabolism						dph	2014-10-01T22:00:29Z						biological_process											owl:Class	
GO:0044610	biolink:NamedThing	FMN transmembrane transporter activity	Enables the directed movement of flavine mononucleotide (FMN) from one side of a membrane to the other.	got7fsn_ti	flavine mononucleotide transmembrane transporter activity						jl	2012-05-30T03:09:19Z						molecular_function											owl:Class	
GO:0001506	biolink:NamedThing	obsolete neurotransmitter biosynthetic process and storage	OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitters and the storage of the synthesized molecules.	got7fsn_ti	neurotransmitter anabolism and storage|neurotransmitter biosynthetic process and storage|neurotransmitter synthesis and storage|neurotransmitter formation and storage				This term was made obsolete because it is an amalgamation of its two children.	GO:0042137|GO:0042136				True				biological_process											owl:Class	
GO:1900653	biolink:NamedThing	negative regulation of demethylkotanin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process.	got7fsn_ti	negative regulation of demethylkotanin formation|inhibition of demethylkotanin biosynthetic process|down regulation of demethylkotanin biosynthetic process|inhibition of demethylkotanin formation|down-regulation of demethylkotanin anabolism|down-regulation of demethylkotanin biosynthesis|negative regulation of demethylkotanin synthesis|downregulation of demethylkotanin biosynthesis|downregulation of demethylkotanin biosynthetic process|down regulation of demethylkotanin synthesis|down-regulation of demethylkotanin formation|down regulation of demethylkotanin biosynthesis|inhibition of demethylkotanin anabolism|downregulation of demethylkotanin formation|down-regulation of demethylkotanin biosynthetic process|inhibition of demethylkotanin synthesis|downregulation of demethylkotanin synthesis|negative regulation of demethylkotanin anabolism|down-regulation of demethylkotanin synthesis|down regulation of demethylkotanin formation|downregulation of demethylkotanin anabolism|inhibition of demethylkotanin biosynthesis|down regulation of demethylkotanin anabolism|negative regulation of demethylkotanin biosynthesis						di	2012-05-22T04:07:41Z						biological_process											owl:Class	
GO:0032416	biolink:NamedThing	negative regulation of sodium:proton antiporter activity	Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).	got7fsn_ti	downregulation of sodium:hydrogen antiporter activity|inhibition of sodium:hydrogen antiporter activity|negative regulation of sodium:hydrogen antiporter activity|down-regulation of sodium:hydrogen antiporter activity|down regulation of sodium:hydrogen antiporter activity													biological_process											owl:Class	
GO:0031561	biolink:NamedThing	cellular bud tip polarisome	Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.	got7fsn_ti														cellular_component											owl:Class	
GO:1900915	biolink:NamedThing	negative regulation of octadecene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process.	got7fsn_ti	downregulation of 1-octadecene biosynthetic process|down regulation of 1-octadecene biosynthetic process|down-regulation of octadecene synthesis|downregulation of octadecene formation|negative regulation of octadecene synthesis|down-regulation of octadecene formation|down-regulation of octadecene anabolism|inhibition of octadecene biosynthetic process|downregulation of octadecene biosynthesis|down regulation of octadecene biosynthesis|down-regulation of 1-octadecene biosynthetic process|down regulation of octadecene anabolism|inhibition of octadecene anabolism|down regulation of octadecene synthesis|inhibition of octadecene synthesis|inhibition of octadecene biosynthesis|downregulation of octadecene anabolism|negative regulation of octadecene biosynthesis|negative regulation of octadecene anabolism|inhibition of 1-octadecene biosynthetic process|downregulation of octadecene synthesis|negative regulation of octadecene formation|negative regulation of 1-octadecene biosynthetic process|down regulation of octadecene biosynthetic process|down regulation of octadecene formation|downregulation of octadecene biosynthetic process|inhibition of octadecene formation|down-regulation of octadecene biosynthetic process|down-regulation of octadecene biosynthesis						tt	2012-06-13T04:24:47Z						biological_process											owl:Class	
GO:1904884	biolink:NamedThing	positive regulation of telomerase catalytic core complex assembly	Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly.	got7fsn_ti	activation of telomerase catalytic core complex assembly|up-regulation of TERT-TERC complex assembly|up regulation of telomerase catalytic core complex assembly|activation of TERT-TERC complex formation|positive regulation of telomerase catalytic core complex formation|upregulation of telomerase catalytic core complex assembly|upregulation of TERT-TERC complex formation|up-regulation of telomerase catalytic core complex formation|positive regulation of TERT-TERC complex formation|up-regulation of TERT-TERC complex formation|positive regulation of TERT-TERC complex assembly|activation of telomerase catalytic core complex formation|upregulation of TERT-TERC complex assembly|activation of TERT-TERC complex assembly|up regulation of TERT-TERC complex assembly|up regulation of telomerase catalytic core complex formation|up regulation of TERT-TERC complex formation|up-regulation of telomerase catalytic core complex assembly|upregulation of telomerase catalytic core complex formation						rph	2016-01-05T10:36:16Z						biological_process											owl:Class	
GO:0075066	biolink:NamedThing	obsolete growth or development of symbiont in host organelle	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's organelle. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of symbiont in host organelle				This term was made obsolete because it contained a conjunction (or).					True				biological_process											owl:Class	
GO:0003840	biolink:NamedThing	obsolete gamma-glutamyltransferase activity	OBSOLETE. Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid.	got7fsn_ti	(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase activity|gamma-GT|glutamyl transpeptidase activity|L-gamma-glutamyltransferase activity|gamma-GTP|alpha-glutamyl transpeptidase activity|gamma-glutamyl peptidyltransferase activity|L-glutamyltransferase activity|gamma-glutamyl transpeptidase activity|L-gamma-glutamyl transpeptidase activity|gamma-GPT				This term was obsoleted because it does not correspond to a physiological reaction. Usage comment: The gene family commonly referred to as gamma-glutamyl transferases (GGT) catalyze hydrolysis of gamma-glutamyl bonds in gamma-glutamyl compounds such as glutathione. In a test tube one can set up conditions in which the enzyme will transfer the gamma-glutamyl portion of the substrate to an acceptor molecule, but this requires non-physiologic conditions, including millmolar concentrations of an acceptor such as glygly. This reaction is used in assays to detect the presence of the enzyme, but is not a physiological function of members of the GGT family (PMC4388159), which should be annotated to a suitable hydrolysis term instead (e.g. glutathione hydrolase activity).	GO:0036374				True		EC:2.3.2.2|MetaCyc:GAMMA-GLUTAMYLTRANSFERASE-RXN|KEGG_REACTION:R04159		molecular_function											owl:Class	
GO:1903196	biolink:NamedThing	negative regulation of L-dopa biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process.	got7fsn_ti	negative regulation of L-dopa synthesis|downregulation of L-dopa biosynthesis|down-regulation of L-dopa formation|down regulation of L-dopa anabolism|inhibition of L-dopa synthesis|downregulation of L-dopa synthesis|negative regulation of L-dopa anabolism|downregulation of L-dopa biosynthetic process|negative regulation of L-dopa formation|down regulation of L-dopa formation|down-regulation of L-dopa biosynthesis|downregulation of L-dopa anabolism|down regulation of L-dopa biosynthetic process|down regulation of L-dopa synthesis|down regulation of L-dopa biosynthesis|inhibition of L-dopa formation|negative regulation of L-dopa biosynthesis|downregulation of L-dopa formation|down-regulation of L-dopa anabolism|down-regulation of L-dopa synthesis|inhibition of L-dopa anabolism|inhibition of L-dopa biosynthetic process|inhibition of L-dopa biosynthesis|down-regulation of L-dopa biosynthetic process						bf	2014-07-21T09:12:44Z						biological_process											owl:Class	
GO:1903265	biolink:NamedThing	positive regulation of tumor necrosis factor-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.	got7fsn_ti	up-regulation of tumor necrosis factor alpha-mediated signaling pathway|upregulation of tumor necrosis factor alpha-mediated signaling pathway|positive regulation of adipocytokine signaling pathway|positive regulation of TNF-alpha-mediated signaling pathway|positive regulation of tumor necrosis factor alpha-mediated signaling pathway|activation of tumor necrosis factor alpha-mediated signaling pathway|up regulation of tumor necrosis factor alpha-mediated signaling pathway|upregulation of tumor necrosis factor-mediated signaling pathway|upregulation of tumor necrosis factor-mediated signalling pathway|activation of adipocytokine signaling pathway|upregulation of adipocytokine signaling pathway|activation of TNF-alpha-mediated signaling pathway|upregulation of TNF-alpha-mediated signaling pathway|up-regulation of adipocytokine signaling pathway|up-regulation of TNF-alpha-mediated signaling pathway|activation of tumor necrosis factor-mediated signaling pathway|positive regulation of tumor necrosis factor-mediated signalling pathway|up regulation of tumor necrosis factor-mediated signalling pathway|up-regulation of tumor necrosis factor-mediated signalling pathway|up regulation of adipocytokine signaling pathway|up regulation of TNF-alpha-mediated signaling pathway|up-regulation of tumor necrosis factor-mediated signaling pathway|activation of tumor necrosis factor-mediated signalling pathway|up regulation of tumor necrosis factor-mediated signaling pathway						bf	2014-08-07T10:26:59Z						biological_process											owl:Class	
GO:0051827	biolink:NamedThing	obsolete growth or development on or near surface of other organism during symbiotic interaction	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	growth or development on or near surface of other organism during symbiotic interaction				This term was made obsolete because it contained a conjunction (or).	GO:0044111				True				biological_process											owl:Class	
GO:2000949	biolink:NamedThing	negative regulation of xyloglucan metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process.	got7fsn_ti	negative regulation of xyloglucan metabolism						tt	2011-08-01T02:16:59Z						biological_process											owl:Class	
GO:0010896	biolink:NamedThing	regulation of triglyceride catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.	got7fsn_ti	regulation of triacylglycerol catabolic process													biological_process											owl:Class	
GO:0032081	biolink:NamedThing	negative regulation of type II site-specific deoxyribonuclease activity	Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity.	got7fsn_ti	down-regulation of type II restriction endodeoxyribonuclease activity|down regulation of type II restriction endodeoxyribonuclease activity|type II restriction endodeoxyribonuclease inhibitor|inhibition of type II restriction endodeoxyribonuclease activity|type II restriction enzyme inhibitor|downregulation of type II restriction endodeoxyribonuclease activity|negative regulation of type II restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0052246	biolink:NamedThing	obsolete positive energy taxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive energy taxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0070614	biolink:NamedThing	tungstate ion transport	The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.	got7fsn_ti							mah	2009-04-29T03:07:40Z						biological_process											owl:Class	
GO:2000172	biolink:NamedThing	regulation of branching morphogenesis of a nerve	Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.	got7fsn_ti							rl	2010-10-07T12:07:54Z						biological_process											owl:Class	
GO:1904767	biolink:NamedThing	octanoic acid binding	Binding to octanoic acid.	got7fsn_ti	caprylic acid binding						kmv	2015-10-27T21:11:49Z						molecular_function											owl:Class	
GO:1905682	biolink:NamedThing	positive regulation of innate immunity memory response	Any process that activates or increases the frequency, rate or extent of innate immunity memory response.	got7fsn_ti	upregulation of innate immunity memory response|up-regulation of innate immunity memory response|activation of innate immunity memory response|up regulation of innate immunity memory response						tb	2016-11-11T22:25:36Z						biological_process											owl:Class	
GO:0030825	biolink:NamedThing	obsolete positive regulation of cGMP metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP.	got7fsn_ti	activation of cGMP metabolic process|positive regulation of cGMP metabolism|upregulation of cGMP metabolic process|up-regulation of cGMP metabolic process|stimulation of cGMP metabolic process|up regulation of cGMP metabolic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0071864	biolink:NamedThing	positive regulation of cell proliferation in bone marrow	A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.	got7fsn_ti	positive regulation of bone marrow cell proliferation|up-regulation of cell proliferation in bone marrow|up regulation of cell proliferation in bone marrow|activation of cell proliferation in bone marrow|upregulation of cell proliferation in bone marrow|stimulation of cell proliferation in bone marrow						mah	2010-09-13T02:12:36Z						biological_process											owl:Class	
GO:0004241	biolink:NamedThing	obsolete alpha-mitochondrial processing peptidase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	alpha-mitochondrial processing peptidase|alpha-MPP				This term was made obsolete because it represents a gene product.	GO:0004222|GO:0005739				True				molecular_function											owl:Class	
GO:1990479	biolink:NamedThing	obsolete response to lipoic acid	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.	got7fsn_ti	response to 5-(1,2-dithiolan-3-yl)pentanoic acid				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-09-09T22:20:41Z		True				biological_process											owl:Class	
GO:0071508	biolink:NamedThing	obsolete activation of MAPK activity involved in conjugation with cellular fusion	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of conjugation with cellular fusion.	got7fsn_ti	activation of MAPK activity involved in mating response|conjugation with cellular fusion, activation of MAPK activity	https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.		mah	2010-01-05T02:09:35Z		True				biological_process											owl:Class	
GO:0019987	biolink:NamedThing	obsolete negative regulation of anti-apoptosis	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of anti-apoptosis.	got7fsn_ti	negative regulation of anti-apoptosis|downregulation of anti-apoptosis|down-regulation of anti-apoptosis|down regulation of anti-apoptosis|inhibition of anti-apoptosis				This term was made obsolete because it was ill-defined.					True				biological_process											owl:Class	
GO:1904992	biolink:NamedThing	positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.	got7fsn_ti	up regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|up-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|activation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|up-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|activation of dopamine receptor, adenylyl cyclase inhibiting pathway|positive regulation of dopamine receptor, adenylate cyclase inhibiting pathway|up regulation of dopamine receptor, adenylate cyclase inhibiting pathway|up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|positive regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|upregulation of dopamine receptor, adenylyl cyclase inhibiting pathway|upregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|activation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|activation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|upregulation of dopamine receptor, adenylate cyclase inhibiting pathway|up-regulation of dopamine receptor, adenylate cyclase inhibiting pathway|up regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|upregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|activation of dopamine receptor, adenylate cyclase inhibiting pathway|upregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway						kmv	2016-02-29T22:42:33Z						biological_process											owl:Class	
GO:1904494	biolink:NamedThing	regulation of substance P secretion, neurotransmission	Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission.	got7fsn_ti							sl	2015-07-21T19:09:04Z						biological_process											owl:Class	
GO:1990494	biolink:NamedThing	obsolete regulation of mitotic cytokinesis, actomyosin contractile ring assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cytokinesis, actomyosin contractile ring assembly.	got7fsn_ti	regulation of mitotic cytokinesis, actomyosin contractile ring assembly				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-09-25T09:04:55Z		True				biological_process											owl:Class	
GO:0051066	biolink:NamedThing	dihydrobiopterin metabolic process	The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.	got7fsn_ti	dihydropterin metabolic process|dihydrobiopterin reduction|dihydropterin metabolism|6,7-dihydrobiopterin metabolic process|7,8-dihydrobiopterin metabolic process													biological_process											owl:Class	
GO:0072321	biolink:NamedThing	obsolete chaperone-mediated protein transport	OBSOLETE. The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20850			This term was obsoleted because it represents a function within a process.	GO:0140597|GO:0015031	mah	2010-10-28T04:23:20Z		True				biological_process											owl:Class	
GO:0045883	biolink:NamedThing	positive regulation of sulfur utilization	Any process that activates or increases the frequency, rate or extent of sulfur utilization.	got7fsn_ti	positive regulation of sulphur utilization|up regulation of sulfur utilization|stimulation of sulfur utilization|up-regulation of sulfur utilization|activation of sulfur utilization|upregulation of sulfur utilization													biological_process											owl:Class	
GO:1900872	biolink:NamedThing	pentadec-1-ene metabolic process	The chemical reactions and pathways involving pentadec-1-ene.	got7fsn_ti	pentadec-1-ene metabolism						tt	2012-06-13T01:45:22Z						biological_process											owl:Class	
GO:0044825	biolink:NamedThing	obsolete retroviral strand transfer activity	OBSOLETE. Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction.	got7fsn_ti	strand transfer reaction	https://github.com/geneontology/go-ontology/issues/21721			This term was obsoleted because it represents part of an activity.	GO:0044823	jl	2014-02-04T15:16:39Z		True				molecular_function											owl:Class	
GO:0000211	biolink:NamedThing	obsolete protein degradation tagging activity	OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction.	got7fsn_ti	protein degradation tagging activity				This term was made obsolete because it represents a biological process and a molecular function.	GO:0019941|GO:0005515				True				molecular_function											owl:Class	
GO:0110003	biolink:NamedThing	regulation of tRNA C5-cytosine methylation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation.	got7fsn_ti							kmv							biological_process											owl:Class	
GO:0090231	biolink:NamedThing	regulation of spindle checkpoint	Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.	got7fsn_ti					Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).		tb	2010-01-20T10:29:43Z						biological_process											owl:Class	
GO:1903902	biolink:NamedThing	positive regulation of viral life cycle	Any process that activates or increases the frequency, rate or extent of viral life cycle.	got7fsn_ti	up-regulation of viral infectious cycle|positive regulation of lytic viral life cycle|positive regulation of viral replication|upregulation of viral assembly, maturation, egress, and release|up regulation of viral life cycle|upregulation of lytic viral life cycle|up regulation of lytic viral life cycle|up-regulation of viral assembly, maturation, egress, and release|positive regulation of viral assembly, maturation, egress, and release|positive regulation of viral infectious cycle|activation of viral replication|up-regulation of viral replication|up regulation of viral replication|up regulation of viral infectious cycle|activation of viral infectious cycle|upregulation of viral infectious cycle|activation of lytic viral life cycle|activation of viral life cycle|upregulation of viral life cycle|up-regulation of lytic viral life cycle|up-regulation of viral life cycle|activation of viral assembly, maturation, egress, and release|up regulation of viral assembly, maturation, egress, and release|upregulation of viral replication						pga	2015-02-09T10:22:25Z						biological_process											owl:Class	
GO:0015393	biolink:NamedThing	obsolete uracil/uridine permease activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	uracil/uridine permease activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0022857|GO:0015213|GO:0015210				True				molecular_function											owl:Class	
GO:0019408	biolink:NamedThing	dolichol biosynthetic process	The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.	got7fsn_ti	dolichol synthesis|dolichol formation|dolichol anabolism|dolichol biosynthesis													biological_process											owl:Class	
GO:1905560	biolink:NamedThing	negative regulation of kinetochore assembly	Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly.	got7fsn_ti	downregulation of centromere and kinetochore complex maturation|inhibition of kinetochore assembly|inhibition of centromere/kinetochore complex maturation|negative regulation of kinetochore formation|inhibition of centromere and kinetochore complex maturation|downregulation of kinetochore assembly|down regulation of kinetochore formation|down regulation of kinetochore assembly|down-regulation of kinetochore assembly|down-regulation of centromere and kinetochore complex maturation|down regulation of centromere/kinetochore complex maturation|down-regulation of kinetochore formation|inhibition of kinetochore formation|down regulation of centromere and kinetochore complex maturation|negative regulation of centromere/kinetochore complex maturation|downregulation of chromosome-kinetochore attachment|down regulation of chromosome-kinetochore attachment|down-regulation of centromere/kinetochore complex maturation|negative regulation of centromere and kinetochore complex maturation|downregulation of kinetochore formation|down-regulation of chromosome-kinetochore attachment|negative regulation of chromosome-kinetochore attachment|down regulation of kinetochore biogenesis|downregulation of centromere/kinetochore complex maturation|inhibition of chromosome-kinetochore attachment						hbye	2016-10-14T13:47:38Z						biological_process											owl:Class	
GO:1905865	biolink:NamedThing	negative regulation of Atg1/ULK1 kinase complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.	got7fsn_ti	negative regulation of ULK1 signaling complex formation|down regulation of ATG1 kinase complex formation|negative regulation of Atg1p signalling complex assembly|negative regulation of ULK1-ATG13-RB1CC1 complex assembly|inhibition of Atg1p signalling complex assembly|downregulation of ULK1-ATG13-RB1CC1 complex formation|down-regulation of ATG1-ATG13 complex formation|downregulation of ULK1-ATG13-FIP200 complex formation|inhibition of ULK1-ATG13-FIP200 complex assembly|down regulation of ULK1 signaling complex formation|inhibition of ATG1-ATG13 complex assembly|down-regulation of ULK1-ATG13-RB1CC1 complex formation|down-regulation of ATG1/ULK1 kinase complex formation|downregulation of Atg1p signalling complex assembly|downregulation of ATG1 kinase complex formation|down regulation of Atg1p signalling complex assembly|downregulation of ATG1/ULK1 signaling complex formation|down-regulation of ULK1 signaling complex assembly|down regulation of ATG1/ULK1 kinase complex formation|negative regulation of ATG1/ULK1 signaling complex assembly|down-regulation of Atg1p signalling complex assembly|down regulation of ATG1-ATG13 complex assembly|down-regulation of ATG1/ULK1 signaling complex assembly|inhibition of ULK1-ATG13-RB1CC1 complex assembly|inhibition of Atg1p signalling complex formation|negative regulation of ULK1-ATG13-FIP200 complex formation|downregulation of ATG1/ULK1 kinase complex formation|down-regulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ULK1-ATG13-RB1CC1 complex formation|downregulation of ATG1-ATG13 complex formation|down-regulation of ULK1-ATG13-FIP200 complex formation|inhibition of ATG1/ULK1 signaling complex formation|inhibition of ATG1/ULK1 signaling complex assembly|inhibition of ATG1/ULK1 kinase complex assembly|down-regulation of ULK1 signaling complex formation|negative regulation of Atg1p signalling complex formation|down regulation of ATG1/ULK1 kinase complex assembly|down regulation of ATG1/ULK1 signaling complex formation|downregulation of ATG1-ATG13 complex assembly|down regulation of ATG1/ULK1 signaling complex assembly|down regulation of ATG1-ATG13 complex formation|down-regulation of ULK1-ATG13-RB1CC1 complex assembly|negative regulation of ATG1-ATG13 complex formation|down-regulation of ATG1/ULK1 kinase complex assembly|down regulation of ULK1-ATG13-RB1CC1 complex assembly|negative regulation of ATG1-ATG13 complex assembly|down regulation of Atg1p signalling complex formation|inhibition of ATG1/ULK1 kinase complex formation|inhibition of ATG1-ATG13 complex formation|downregulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ULK1 signaling complex assembly|negative regulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ATG1/ULK1 signaling complex formation|down-regulation of ATG1 kinase complex assembly|downregulation of ATG1/ULK1 kinase complex assembly|downregulation of ULK1 signaling complex formation|downregulation of ATG1 kinase complex assembly|downregulation of ULK1-ATG13-RB1CC1 complex assembly|down-regulation of ATG1-ATG13 complex assembly|down regulation of ATG1 kinase complex assembly|inhibition of ATG1 kinase complex formation|inhibition of ULK1-ATG13-RB1CC1 complex formation|down-regulation of ATG1/ULK1 signaling complex formation|down regulation of ULK1-ATG13-FIP200 complex formation|downregulation of Atg1p signalling complex formation|downregulation of ATG1/ULK1 signaling complex assembly|down regulation of ULK1-ATG13-RB1CC1 complex formation|inhibition of ULK1 signaling complex formation|negative regulation of ATG1 kinase complex assembly|negative regulation of ATG1 kinase complex formation|down-regulation of Atg1p signalling complex formation|inhibition of ATG1 kinase complex assembly|negative regulation of ATG1/ULK1 kinase complex formation|down regulation of ULK1-ATG13-FIP200 complex assembly|down-regulation of ATG1 kinase complex formation|inhibition of ULK1-ATG13-FIP200 complex formation|inhibition of ULK1 signaling complex assembly|downregulation of ULK1 signaling complex assembly|down regulation of ULK1 signaling complex assembly						pr	2017-01-26T13:23:35Z						biological_process											owl:Class	
GO:2000332	biolink:NamedThing	regulation of blood microparticle formation	Any process that modulates the frequency, rate or extent of blood microparticle formation.	got7fsn_ti	regulation of microparticle release|regulation of microparticle generation						mah	2011-01-31T11:18:11Z						biological_process											owl:Class	
CHEBI:143624	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000517	biolink:NamedThing	regulation of T-helper 1 cell activation	Any process that modulates the frequency, rate or extent of T-helper 1 cell activation.	got7fsn_ti	regulation of Th1 cell activation						ebc	2011-03-22T10:40:19Z						biological_process											owl:Class	
GO:1903923	biolink:NamedThing	positive regulation of protein processing in phagocytic vesicle	Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle.	got7fsn_ti	up regulation of protein processing in phagosome|upregulation of protein maturation by peptide bond cleavage in phagocytic vesicle|up-regulation of protein processing in phagocytic vesicle|up-regulation of protein maturation by peptide bond hydrolysis in phagosome|up-regulation of peptidolysis during protein maturation in phagosome|upregulation of protein maturation by peptide bond hydrolysis in phagosome|activation of protein maturation by peptide bond cleavage in phagosome|positive regulation of protein maturation by peptide bond hydrolysis in phagosome|positive regulation of protein maturation by peptide bond cleavage in phagosome|activation of protein maturation by proteolysis in phagocytic vesicle|positive regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|positive regulation of protein maturation by proteolysis in phagocytic vesicle|activation of peptidolysis during protein maturation in phagocytic vesicle|activation of peptidolysis during protein maturation in phagosome|activation of protein processing in phagocytic vesicle|activation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|upregulation of protein maturation by peptide bond cleavage in phagosome|positive regulation of protein maturation by proteolysis in phagosome|up regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|upregulation of peptidolysis during protein maturation in phagocytic vesicle|up regulation of protein processing in phagocytic vesicle|activation of protein maturation by proteolysis in phagosome|positive regulation of protein processing in phagosome|up-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|upregulation of peptidolysis during protein maturation in phagosome|up-regulation of protein maturation by proteolysis in phagosome|up regulation of peptidolysis during protein maturation in phagosome|up regulation of protein maturation by peptide bond hydrolysis in phagosome|upregulation of protein processing in phagocytic vesicle|up-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|positive regulation of peptidolysis during protein maturation in phagocytic vesicle|up-regulation of peptidolysis during protein maturation in phagocytic vesicle|upregulation of protein maturation by proteolysis in phagosome|positive regulation of peptidolysis during protein maturation in phagosome|activation of protein maturation by peptide bond hydrolysis in phagosome|activation of protein maturation by peptide bond cleavage in phagocytic vesicle|up-regulation of protein processing in phagosome|upregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up regulation of protein maturation by proteolysis in phagosome|up regulation of protein maturation by peptide bond cleavage in phagosome|up regulation of peptidolysis during protein maturation in phagocytic vesicle|up regulation of protein maturation by proteolysis in phagocytic vesicle|up-regulation of protein maturation by proteolysis in phagocytic vesicle|up-regulation of protein maturation by peptide bond cleavage in phagosome|positive regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|upregulation of protein processing in phagosome|activation of protein processing in phagosome|upregulation of protein maturation by proteolysis in phagocytic vesicle						als	2015-02-10T11:17:14Z						biological_process											owl:Class	
GO:1904968	biolink:NamedThing	positive regulation of monopolar spindle attachment to meiosis I kinetochore	Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.	got7fsn_ti	up-regulation of attachment of spindle microtubules to kinetochore during meiosis I|up regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|upregulation of monopolar attachment|up regulation of attachment of spindle microtubules to kinetochore during meiosis I|upregulation of sister kinetochore mono-orientation|positive regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|activation of attachment of spindle microtubules to kinetochore involved in meiosis I|upregulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|activation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|upregulation of attachment of spindle microtubules to kinetochore during meiosis I|up-regulation of monopolar attachment|up-regulation of sister kinetochore mono-orientation|up-regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|positive regulation of monopolar attachment|activation of attachment of spindle microtubules to kinetochore during meiosis I|up regulation of sister kinetochore mono-orientation|up-regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|positive regulation of attachment of spindle microtubules to kinetochore during meiosis I|positive regulation of sister kinetochore mono-orientation|upregulation of attachment of spindle microtubules to kinetochore involved in meiosis I|up regulation of monopolar attachment|activation of sister kinetochore mono-orientation|activation of monopolar attachment|positive regulation of attachment of spindle microtubules to kinetochore involved in meiosis I						mah	2016-02-15T15:19:20Z						biological_process											owl:Class	
GO:1901209	biolink:NamedThing	positive regulation of heart looping	Any process that activates or increases the frequency, rate or extent of heart looping.	got7fsn_ti	up regulation of cardiac looping|positive regulation of cardiac looping|up-regulation of cardiac looping|activation of heart looping|activation of cardiac looping|upregulation of heart looping|up regulation of heart looping|upregulation of cardiac looping|up-regulation of heart looping						rl	2012-07-31T07:16:18Z						biological_process											owl:Class	
GO:2000105	biolink:NamedThing	positive regulation of DNA-dependent DNA replication	Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication.	got7fsn_ti							mah	2010-09-15T01:37:10Z						biological_process											owl:Class	
GO:1900943	biolink:NamedThing	positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process	Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.	got7fsn_ti	up regulation of (Z)-nonadeca-1,14-diene synthesis|activation of (Z)-nonadeca-1,14-diene formation|up-regulation of (Z)-nonadeca-1,14-diene anabolism|up regulation of (Z)-nonadeca-1,14-diene formation|upregulation of (Z)-nonadeca-1,14-diene synthesis|upregulation of (Z)-nonadeca-1,14-diene anabolism|up-regulation of (Z)-nonadeca-1,14-diene formation|up regulation of (Z)-nonadeca-1,14-diene anabolism|activation of (Z)-nonadeca-1,14-diene anabolism|activation of (Z)-nonadeca-1,14-diene synthesis|upregulation of (Z)-nonadeca-1,14-diene biosynthetic process|positive regulation of (Z)-nonadeca-1,14-diene biosynthesis|positive regulation of (Z)-nonadeca-1,14-diene anabolism|up-regulation of (Z)-nonadeca-1,14-diene biosynthetic process|up regulation of (Z)-nonadeca-1,14-diene biosynthesis|activation of (Z)-nonadeca-1,14-diene biosynthesis|up-regulation of (Z)-nonadeca-1,14-diene synthesis|upregulation of (Z)-nonadeca-1,14-diene biosynthesis|positive regulation of (Z)-nonadeca-1,14-diene synthesis|activation of (Z)-nonadeca-1,14-diene biosynthetic process|up regulation of (Z)-nonadeca-1,14-diene biosynthetic process|upregulation of (Z)-nonadeca-1,14-diene formation|positive regulation of (Z)-nonadeca-1,14-diene formation|up-regulation of (Z)-nonadeca-1,14-diene biosynthesis						tt	2012-06-14T03:18:01Z						biological_process											owl:Class	
OBO:OBA_0000117	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905446	biolink:NamedThing	regulation of mitochondrial ATP synthesis coupled electron transport	Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.	got7fsn_ti	regulation of organelle ATP synthesis coupled electron transport|regulation of mitochondrial electron transport						dph	2016-09-15T18:57:58Z						biological_process											owl:Class	
GO:1905203	biolink:NamedThing	regulation of connective tissue replacement	Any process that modulates the frequency, rate or extent of connective tissue replacement.	got7fsn_ti							bc	2016-05-17T09:54:18Z						biological_process											owl:Class	
GO:0002654	biolink:NamedThing	positive regulation of tolerance induction dependent upon immune response	Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.	got7fsn_ti	up-regulation of tolerance induction dependent upon immune response|upregulation of tolerance induction dependent upon immune response|stimulation of tolerance induction dependent upon immune response|positive regulation of immune response-dependent tolerance induction|up regulation of tolerance induction dependent upon immune response|activation of tolerance induction dependent upon immune response													biological_process											owl:Class	
GO:0001323	biolink:NamedThing	obsolete age-dependent general metabolic decline involved in chronological cell aging	OBSOLETE. A process of general metabolic decline that arises in non-dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.	got7fsn_ti	age-dependent general metabolic decline during chronological cell ageing|age-dependent general metabolic decline during chronological cell aging	https://github.com/geneontology/go-ontology/issues/18632			This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0090398|GO:0044838				True				biological_process											owl:Class	
GO:1902055	biolink:NamedThing	positive regulation of neosartoricin biosynthetic process	Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process.	got7fsn_ti	up regulation of neosartoricin anabolism|positive regulation of neosartoricin anabolism|up-regulation of neosartoricin anabolism|upregulation of neosartoricin anabolism|up regulation of neosartoricin biosynthesis|activation of neosartoricin biosynthesis|up regulation of neosartoricin biosynthetic process|activation of neosartoricin synthesis|activation of neosartoricin biosynthetic process|activation of neosartoricin anabolism|positive regulation of neosartoricin synthesis|positive regulation of neosartoricin biosynthesis|up regulation of neosartoricin formation|upregulation of neosartoricin formation|up-regulation of neosartoricin biosynthetic process|upregulation of neosartoricin biosynthetic process|up-regulation of neosartoricin synthesis|upregulation of neosartoricin biosynthesis|activation of neosartoricin formation|up-regulation of neosartoricin biosynthesis|up regulation of neosartoricin synthesis|up-regulation of neosartoricin formation|positive regulation of neosartoricin formation|upregulation of neosartoricin synthesis						di	2013-04-11T15:46:20Z						biological_process											owl:Class	
GO:1900750	biolink:NamedThing	oligopeptide binding	Binding to an oligopeptide.	got7fsn_ti	Oligopeptid binding|oligopeptido binding|oligopeptides binding						jl	2012-05-29T02:13:31Z						molecular_function											owl:Class	
GO:1905697	biolink:NamedThing	negative regulation of polysome binding	Any process that stops, prevents or reduces the frequency, rate or extent of polysome binding.	got7fsn_ti	negative regulation of polyribosome binding|down-regulation of polysome binding|downregulation of polysome binding|inhibition of polysome binding|down regulation of polysome binding|down-regulation of polyribosome binding|inhibition of polyribosome binding|down regulation of polyribosome binding|downregulation of polyribosome binding						bc	2016-11-14T23:26:29Z						biological_process											owl:Class	
GO:1902354	biolink:NamedThing	blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment	Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment.	got7fsn_ti							pr	2013-08-14T10:22:00Z						biological_process											owl:Class	
GO:1904896	biolink:NamedThing	ESCRT complex disassembly	The disaggregation of an ESCRT complex into its constituent components.	got7fsn_ti	endosomal sorting complex required for transport disassembly						pad	2016-01-12T10:27:30Z						biological_process											owl:Class	
GO:2000042	biolink:NamedThing	negative regulation of double-strand break repair via homologous recombination	Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.	got7fsn_ti	negative regulation of homology-directed repair|negative regulation of HRR|negative regulation of homologous recombinational repair|negative regulation of Rhp51-dependent recombinational repair|negative regulation of Rad51-dependent recombinational repair|negative regulation of HDR						tb	2010-08-19T06:37:08Z						biological_process											owl:Class	
CHEBI:60869	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901055	biolink:NamedThing	trimethylenediamine metabolic process	The chemical reactions and pathways involving trimethylenediamine.	got7fsn_ti	trimethylenediamine metabolism						yaf	2012-06-28T04:52:42Z						biological_process											owl:Class	
GO:0004299	biolink:NamedThing	obsolete proteasome endopeptidase activity	OBSOLETE. Catalysis of the cleavage at peptide bonds with very broad specificity.	got7fsn_ti	proteasome endopeptidase complex|multicatalytic endopeptidase|proteasome endopeptidase activity|proteasome				This term was made obsolete because it mentions a component term in the text string.	GO:0004175|GO:0008233				True				molecular_function											owl:Class	
GO:0034161	biolink:NamedThing	positive regulation of toll-like receptor 8 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway.	got7fsn_ti	positive regulation of toll-like receptor 8 signalling pathway|positive regulation of TLR8 signaling pathway													biological_process											owl:Class	
GO:1902022	biolink:NamedThing	L-lysine transport	The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							kmv	2013-03-27T16:09:06Z						biological_process											owl:Class	
GO:1900704	biolink:NamedThing	regulation of siderophore biosynthetic process	Any process that modulates the frequency, rate or extent of siderophore biosynthetic process.	got7fsn_ti	regulation of siderophore synthesis|regulation of siderochrome biosynthetic process|regulation of siderophore anabolism|regulation of siderophore biosynthetic process, peptide formation|regulation of siderochrome biosynthesis|regulation of siderophore formation|regulation of siderophore biosynthesis|regulation of siderophore biosynthetic process, peptide modification						di	2012-05-22T04:59:28Z						biological_process											owl:Class	
GO:1901985	biolink:NamedThing	positive regulation of protein acetylation	Any process that activates or increases the frequency, rate or extent of protein acetylation.	got7fsn_ti	activation of protein amino acid acetylation|upregulation of protein acetylation|activation of protein acetylation|up regulation of protein acetylation|positive regulation of protein amino acid acetylation|up regulation of protein amino acid acetylation|upregulation of protein amino acid acetylation|up-regulation of protein acetylation|up-regulation of protein amino acid acetylation						ss	2013-03-14T00:40:19Z						biological_process											owl:Class	
GO:0071793	biolink:NamedThing	bacillithiol biosynthetic process	The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.	got7fsn_ti	bacillithiol biosynthesis|bacillithiol formation|bacillithiol anabolism|bacillithiol synthesis						mah	2010-09-02T11:16:04Z						biological_process											owl:Class	
GO:0006668	biolink:NamedThing	sphinganine-1-phosphate metabolic process	The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.	got7fsn_ti	dihydrosphingosine-1-phosphate metabolic process|dihydrosphingosine-1-phosphate metabolism|sphinganine-1-phosphate metabolism													biological_process											owl:Class	
GO:1904099	biolink:NamedThing	negative regulation of protein O-linked glycosylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation.	got7fsn_ti	downregulation of protein O-linked glycosylation|down regulation of protein O-linked glycosylation|down regulation of protein amino acid O-linked glycosylation|downregulation of protein amino acid O-linked glycosylation|inhibition of protein O-linked glycosylation|inhibition of protein amino acid O-linked glycosylation|down-regulation of protein amino acid O-linked glycosylation|down-regulation of protein O-linked glycosylation|negative regulation of protein amino acid O-linked glycosylation						krc	2015-03-27T16:10:04Z						biological_process											owl:Class	
GO:0106062	biolink:NamedThing	positive regulation of exit from meiosis	Any process that activates or increases the frequency, rate or extent of exit from meiosis.	got7fsn_ti							hjd	2017-10-18T16:57:01Z						biological_process											owl:Class	
GO:1901947	biolink:NamedThing	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process	The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.	got7fsn_ti	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolism						ms	2013-02-18T15:50:41Z						biological_process											owl:Class	
GO:1905820	biolink:NamedThing	positive regulation of chromosome separation	Any process that activates or increases the frequency, rate or extent of chromosome separation.	got7fsn_ti	up regulation of rDNA separation|activation of chromosome separation|up regulation of chromosome separation|upregulation of chromosome separation|upregulation of rDNA separation|up-regulation of rDNA separation|activation of chromatid release|positive regulation of rDNA separation|positive regulation of chromatid release|activation of rDNA separation|upregulation of chromatid release|up-regulation of chromosome separation|up regulation of chromatid release|up-regulation of chromatid release						bhm	2017-01-13T13:55:36Z						biological_process											owl:Class	
GO:2001296	biolink:NamedThing	N(omega)-methyl-L-arginine metabolic process	The chemical reactions and pathways involving N(omega)-methyl-L-arginine.	got7fsn_ti	N(omega)-methyl-L-arginine metabolism						pr	2012-02-14T03:38:16Z						biological_process											owl:Class	
GO:0016164	biolink:NamedThing	obsolete Mo-molybdopterin oxidoreductase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	molybdopterin oxidoreductase activity|Mo-molybdopterin oxidoreductase activity			GO:0016491	This term was made obsolete because the differentia from the parent is a gene product feature (specifically, the presence of a molybdopterin cofactor in the protein). It has also never been defined.					True				molecular_function											owl:Class	
GO:0060548	biolink:NamedThing	negative regulation of cell death	Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.	got7fsn_ti							dph	2009-04-13T01:56:10Z						biological_process											owl:Class	
GO:0106090	biolink:NamedThing	positive regulation of cell adhesion involved in sprouting angiogenesis	Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.	got7fsn_ti							hjd	2018-01-22T18:31:02Z						biological_process											owl:Class	
GO:1904874	biolink:NamedThing	positive regulation of telomerase RNA localization to Cajal body	Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.	got7fsn_ti	up regulation of telomerase RNA localization to Cajal body|activation of telomerase RNA localization to Cajal body|up-regulation of telomerase RNA localization to Cajal body|upregulation of telomerase RNA localization to Cajal body						nc	2015-12-18T11:28:34Z						biological_process											owl:Class	
GO:1904855	biolink:NamedThing	proteasome regulatory particle binding	Binding to a proteasome regulatory particle.	got7fsn_ti	PA700-dependent proteasome activator binding|19S regulatory particle binding|modulator complex binding|PA700 proteasome activator binding						mah	2015-12-15T11:54:27Z						molecular_function											owl:Class	
GO:0043645	biolink:NamedThing	cephalosporin metabolic process	The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.	got7fsn_ti	cephalosporin metabolism													biological_process											owl:Class	
GO:0006495	biolink:NamedThing	obsolete terminal O-glycosylation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	terminal O-glycosylation				This term was made obsolete because there is no evidence for the existence of this process.					True				biological_process											owl:Class	
GO:1990881	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to DNA damage	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage.	got7fsn_ti	downregulation of transcription from RNA polymerase II promoter in response to DNA damage|down regulation of transcription from RNA polymerase II promoter in response to DNA damage|down-regulation of transcription from RNA polymerase II promoter in response to DNA damage|inhibition of transcription from RNA polymerase II promoter in response to DNA damage				This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0000122|GO:0006974	mcc	2015-10-28T13:02:18Z		True				biological_process											owl:Class	
GO:0061293	biolink:NamedThing	canonical Wnt signaling pathway involved in mesonephric nephron development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	got7fsn_ti	canonical Wnt-activated signaling pathway involved in mesonephric nephron development|canonical Wnt receptor signalling pathway involved in mesonephric nephron development|canonical Wnt receptor signaling pathway involved in mesonephric nephron development						dph	2010-09-03T12:49:43Z						biological_process											owl:Class	
GO:0042232	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031135	biolink:NamedThing	negative regulation of conjugation	Any process that decreases the rate of conjugation.	got7fsn_ti	downregulation of conjugation|down-regulation of conjugation|down regulation of conjugation|inhibition of conjugation													biological_process											owl:Class	
GO:1904249	biolink:NamedThing	negative regulation of age-related resistance	Any process that stops, prevents or reduces the extent of age-related resistance.	got7fsn_ti	downregulation of flowering-induced resistance|down-regulation of age-related resistance|negative regulation of ARR|inhibition of mature seedling resistance|down-regulation of flowering-induced resistance|downregulation of mature seedling resistance|negative regulation of flowering-induced resistance|down regulation of ARR|down regulation of adult seedling resistance|down regulation of age-related resistance|inhibition of ARR|inhibition of age-related resistance|inhibition of senescence-induced resistance|inhibition of flowering-induced resistance|negative regulation of senescence-induced resistance|down regulation of flowering-induced resistance|negative regulation of adult seedling resistance|down-regulation of ARR|downregulation of age-related resistance|downregulation of senescence-induced resistance|downregulation of ARR|down-regulation of mature seedling resistance|down-regulation of senescence-induced resistance|down-regulation of adult seedling resistance|negative regulation of mature seedling resistance|down regulation of mature seedling resistance|downregulation of adult seedling resistance|inhibition of adult seedling resistance|down regulation of senescence-induced resistance						tb	2015-05-19T20:20:05Z						biological_process											owl:Class	
UBERON:0001899	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905829	biolink:NamedThing	negative regulation of prostaglandin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process.	got7fsn_ti	down regulation of prostaglandin degradation|down-regulation of prostaglandin degradation|inhibition of prostaglandin catabolism|negative regulation of prostaglandin degradation|downregulation of prostaglandin degradation|down-regulation of prostaglandin catabolic process|downregulation of prostaglandin catabolism|negative regulation of prostaglandin breakdown|negative regulation of prostaglandin catabolism|down regulation of prostaglandin catabolic process|inhibition of prostaglandin degradation|downregulation of prostaglandin catabolic process|down-regulation of prostaglandin catabolism|inhibition of prostaglandin breakdown|down regulation of prostaglandin catabolism|down regulation of prostaglandin breakdown|downregulation of prostaglandin breakdown|down-regulation of prostaglandin breakdown|inhibition of prostaglandin catabolic process						sl	2017-01-16T21:36:48Z						biological_process											owl:Class	
GO:0015892	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0100032	biolink:NamedThing	obsolete positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phospholipid biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0070234	biolink:NamedThing	positive regulation of T cell apoptotic process	Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.	got7fsn_ti	positive regulation of T cell apoptosis|stimulation of T cell apoptosis|up-regulation of T cell apoptosis|upregulation of T cell apoptosis|activation of T cell apoptosis|positive regulation of T lymphocyte apoptosis|up regulation of T cell apoptosis|positive regulation of T-lymphocyte apoptosis|positive regulation of T-cell apoptosis|positive regulation of programmed cell death of T cells by apoptosis													biological_process											owl:Class	
GO:1903103	biolink:NamedThing	potassium:proton antiporter complex	A protein complex which is capable of potassium:proton antiporter activity.	got7fsn_ti					An example of this is kefC in E. coli (P03819) in PMID:21041667 (inferred from direct assay).		bhm	2014-06-04T20:51:33Z						cellular_component											owl:Class	
GO:1904723	biolink:NamedThing	negative regulation of Wnt-Frizzled-LRP5/6 complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.	got7fsn_ti	down regulation of WNT-FZD-LRP5 complex assembly|inhibition of WNT-FZD-LRP6 complex formation|negative regulation of WNT-FZD-LRP5 complex formation|downregulation of WNT-FZD-LRP5 complex assembly|down regulation of Wnt-FZD-LRP5/6 trimeric complex formation|inhibition of Frizzled-LRP5/6 complex assembly|down-regulation of WNT-FZD-LRP6 complex formation|down regulation of Wnt-induced Frizzled-LRP5/6 complex formation|inhibition of Frizzled-LRP5/6 complex formation|down regulation of WNT-FZD-LRP5 complex formation|downregulation of WNT-FZD-LRP5 complex formation|downregulation of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|inhibition of WNT-FZD-LRP5 complex assembly|inhibition of WNT-FZD-LRP6 complex assembly|down-regulation of Frizzled-LRP5/6 complex formation|downregulation of Frizzled-LRP5/6 complex formation|negative regulation of WNT-FZD-LRP5 complex assembly|inhibition of Wnt-induced Frizzled-LRP5/6 complex assembly|down-regulation of Wnt-induced Frizzled-LRP5/6 complex formation|downregulation of Wnt-induced Frizzled-LRP5/6 complex assembly|down regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|downregulation of Wnt-induced Frizzled-LRP5/6 complex formation|down-regulation of WNT-FZD-LRP5 complex formation|down regulation of Frizzled-LRP5/6 complex formation|down-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|negative regulation of Frizzled-LRP5/6 complex assembly|down regulation of WNT-FZD-LRP6 complex formation|downregulation of Wnt-FZD-LRP5/6 trimeric complex assembly|negative regulation of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of Wnt-FZD-LRP5/6 trimeric complex formation|negative regulation of Frizzled-LRP5/6 complex formation|negative regulation of WNT-FZD-LRP6 complex assembly|down-regulation of Frizzled-LRP5/6 complex assembly|negative regulation of WNT-FZD-LRP6 complex formation|down regulation of Frizzled-LRP5/6 complex assembly|inhibition of Wnt-induced Frizzled-LRP5/6 complex formation|down-regulation of WNT-FZD-LRP5 complex assembly|negative regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|down regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|negative regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|down regulation of WNT-FZD-LRP6 complex assembly|downregulation of WNT-FZD-LRP6 complex assembly|downregulation of Frizzled-LRP5/6 complex assembly|inhibition of Wnt-FZD-LRP5/6 trimeric complex formation|inhibition of Wnt-FZD-LRP5/6 trimeric complex assembly|inhibition of WNT-FZD-LRP5 complex formation|negative regulation of Wnt-induced Frizzled-LRP5/6 complex formation|down-regulation of WNT-FZD-LRP6 complex assembly|downregulation of WNT-FZD-LRP6 complex formation						bf	2015-10-12T08:14:59Z						biological_process											owl:Class	
GO:2000669	biolink:NamedThing	negative regulation of dendritic cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.	got7fsn_ti	negative regulation of dendritic cell apoptosis						pr	2011-05-09T07:34:21Z						biological_process											owl:Class	
GO:1904337	biolink:NamedThing	positive regulation of ductus arteriosus closure	Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure.	got7fsn_ti	up-regulation of ductus arteriosus closure|activation of ductus arteriosus closure|up regulation of ductus arteriosus closure|upregulation of ductus arteriosus closure						sl	2015-06-11T17:45:27Z						biological_process											owl:Class	
GO:1903138	biolink:NamedThing	negative regulation of cell wall integrity MAPK cascade	Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.	got7fsn_ti	down-regulation of MAPK cascade involved in cell wall biogenesis|down-regulation of MAPKKK cascade involved in cell wall biogenesis|down regulation of cell integrity MAPK pathway|down-regulation of cell wall biogenesis, MAPKKK cascade|negative regulation of Pmk1 MAPK cell integrity signaling|downregulation of cell wall biogenesis, MAPKKK cascade|down regulation of MAPKKK cascade involved in cell wall biogenesis|downregulation of Pmk1 MAPK cell integrity signaling|negative regulation of MAPK cascade involved in cell wall organization or biogenesis|inhibition of PMK1-MAPK signal transduction pathway|down regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|downregulation of PMK1-MAPK signal transduction pathway|inhibition of cell integrity MAPK pathway|down-regulation of Pmk1 MAPK cell integrity signaling|inhibition of MAPK cascade involved in cell wall organization or biogenesis|inhibition of MAPKKK cascade involved in cell wall biogenesis|downregulation of Mpk1 cascade|downregulation of MAPKKK cascade involved in cell wall biogenesis|negative regulation of MAPK cascade involved in cell wall biogenesis|down-regulation of PMK1-MAPK signal transduction pathway|down-regulation of Slt2 cascade|negative regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|down-regulation of MAPK cascade involved in cell wall organization or biogenesis|down regulation of PMK1-MAPK signal transduction pathway|down-regulation of Mpk1 cascade|down-regulation of cell integrity MAPK pathway|downregulation of MAPK cascade involved in cell wall biogenesis|negative regulation of cell wall biogenesis, MAPKKK cascade|down regulation of Mpk1 cascade|downregulation of MAPK cascade involved in cell wall organization or biogenesis|downregulation of cell integrity MAPK pathway|down regulation of Pmk1 MAPK cell integrity signaling|inhibition of Pmk1 MAPK cell integrity signaling|down regulation of MAPK cascade involved in cell wall organization or biogenesis|negative regulation of PMK1-MAPK signal transduction pathway|negative regulation of Slt2 cascade|inhibition of cell wall biogenesis, MAPKKK cascade|inhibition of Mpk1 cascade|down-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|negative regulation of Mpk1 cascade|down regulation of Slt2 cascade|inhibition of MAPK cascade involved in cell wall biogenesis|negative regulation of MAPKKK cascade involved in cell wall biogenesis|down regulation of MAPK cascade involved in cell wall biogenesis|inhibition of Slt2 cascade|negative regulation of cell integrity MAPK pathway|downregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|down regulation of cell wall biogenesis, MAPKKK cascade|downregulation of Slt2 cascade|inhibition of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway	https://github.com/geneontology/go-ontology/issues/20131					mah	2014-07-01T10:21:59Z						biological_process											owl:Class	
GO:0052414	biolink:NamedThing	obsolete metabolism by host of symbiont glucan	OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0052234	biolink:NamedThing	obsolete negative aerotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative aerotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0045164	biolink:NamedThing	obsolete secretin (sensu Mammalia)	OBSOLETE. Secretin is a hormone that takes part in the digestion process. It also has effects on organs other than gastrointestinal tract.	got7fsn_ti	secretin (sensu Mammalia)				This term was made obsolete because it represents a gene product rather than a molecular function.	GO:0046659				True				molecular_function											owl:Class	
GO:1903367	biolink:NamedThing	positive regulation of fear response	Any process that activates or increases the frequency, rate or extent of fear response.	got7fsn_ti	positive regulation of physiological fear response|upregulation of physiological fear response|up regulation of physiological fear response|activation of fear response|activation of physiological fear response|up-regulation of fear response|up regulation of fear response|upregulation of fear response|up-regulation of physiological fear response						mr	2014-08-21T23:21:53Z						biological_process											owl:Class	
GO:1903267	biolink:NamedThing	negative regulation of ornithine catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process.	got7fsn_ti	down-regulation of ornithine catabolism|inhibition of ornithine degradation|negative regulation of ornithine catabolism|inhibition of ornithine catabolic process|down regulation of ornithine catabolism|downregulation of ornithine catabolic process|down regulation of ornithine breakdown|negative regulation of ornithine degradation|downregulation of ornithine breakdown|inhibition of ornithine breakdown|downregulation of ornithine catabolism|down regulation of ornithine catabolic process|down regulation of ornithine degradation|down-regulation of ornithine breakdown|down-regulation of ornithine catabolic process|downregulation of ornithine degradation|negative regulation of ornithine breakdown|down-regulation of ornithine degradation|inhibition of ornithine catabolism				An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay).		bhm	2014-08-08T08:29:42Z						biological_process											owl:Class	
GO:0032824	biolink:NamedThing	negative regulation of natural killer cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation.	got7fsn_ti	down-regulation of natural killer cell differentiation|negative regulation of natural killer cell development|inhibition of natural killer cell differentiation|downregulation of natural killer cell differentiation|down regulation of natural killer cell differentiation|negative regulation of NK cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1905859	biolink:NamedThing	negative regulation of heparan sulfate proteoglycan binding	Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding.	got7fsn_ti	down regulation of heparan sulfate proteoglycan binding|down-regulation of heparin proteoglycan binding|downregulation of heparan sulfate proteoglycan binding|inhibition of heparan sulfate proteoglycan binding|down regulation of heparin proteoglycan binding|down-regulation of heparan sulfate proteoglycan binding|downregulation of heparin proteoglycan binding|negative regulation of heparin proteoglycan binding|inhibition of heparin proteoglycan binding						bc	2017-01-23T14:25:19Z						biological_process											owl:Class	
GO:1902689	biolink:NamedThing	negative regulation of NAD metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process.	got7fsn_ti	down-regulation of NAD metabolic process|down-regulation of NAD (oxidized) metabolism|inhibition of nicotinamide adenine dinucleotide metabolic process|negative regulation of nicotinamide adenine dinucleotide metabolism|negative regulation of oxidized NAD metabolic process|down regulation of nicotinamide adenine dinucleotide metabolic process|downregulation of oxidized NAD metabolism|downregulation of NAD metabolism|negative regulation of oxidized NAD metabolism|inhibition of NAD metabolic process|down-regulation of oxidized NAD metabolic process|downregulation of NAD (oxidized) metabolism|down-regulation of NAD phosphorylation and dephosphorylation|inhibition of NAD phosphorylation and dephosphorylation|down-regulation of nicotinamide adenine dinucleotide metabolic process|down-regulation of nicotinamide adenine dinucleotide metabolism|down-regulation of oxidized nicotinamide adenine dinucleotide metabolism|down regulation of NAD metabolic process|downregulation of oxidized nicotinamide adenine dinucleotide metabolic process|down regulation of oxidized nicotinamide adenine dinucleotide metabolism|down regulation of oxidized NAD metabolism|down-regulation of NAD metabolism|inhibition of oxidized nicotinamide adenine dinucleotide metabolism|inhibition of oxidized NAD metabolic process|down-regulation of oxidized NAD metabolism|negative regulation of oxidized nicotinamide adenine dinucleotide metabolic process|negative regulation of nicotinamide adenine dinucleotide metabolic process|negative regulation of NAD metabolism|downregulation of oxidized NAD metabolic process|negative regulation of NAD (oxidized) metabolism|down regulation of nicotinamide adenine dinucleotide metabolism|down regulation of oxidized nicotinamide adenine dinucleotide metabolic process|downregulation of NAD phosphorylation and dephosphorylation|inhibition of NAD (oxidized) metabolic process|down regulation of NAD (oxidized) metabolic process|negative regulation of oxidized nicotinamide adenine dinucleotide metabolism|negative regulation of NAD phosphorylation and dephosphorylation|downregulation of NAD (oxidized) metabolic process|down regulation of NAD phosphorylation and dephosphorylation|downregulation of nicotinamide adenine dinucleotide metabolic process|down regulation of NAD metabolism|negative regulation of NAD (oxidized) metabolic process|downregulation of NAD metabolic process|down regulation of NAD (oxidized) metabolism|inhibition of oxidized NAD metabolism|inhibition of oxidized nicotinamide adenine dinucleotide metabolic process|down-regulation of oxidized nicotinamide adenine dinucleotide metabolic process|inhibition of NAD (oxidized) metabolism|downregulation of oxidized nicotinamide adenine dinucleotide metabolism|inhibition of nicotinamide adenine dinucleotide metabolism|downregulation of nicotinamide adenine dinucleotide metabolism|inhibition of NAD metabolism|down regulation of oxidized NAD metabolic process|down-regulation of NAD (oxidized) metabolic process						di	2014-02-12T18:58:59Z						biological_process											owl:Class	
GO:1900189	biolink:NamedThing	positive regulation of cell adhesion involved in single-species biofilm formation	Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.	got7fsn_ti	upregulation of cell adhesion during single-species biofilm formation|positive regulation of cell adhesion during single-species biofilm formation|up regulation of cell adhesion during single-species biofilm formation|upregulation of cell adhesion involved in single-species biofilm formation|up-regulation of cell adhesion involved in single-species biofilm formation|activation of cell adhesion during single-species biofilm formation|up regulation of cell adhesion involved in single-species biofilm formation|up-regulation of cell adhesion during single-species biofilm formation|activation of cell adhesion involved in single-species biofilm formation						di	2012-03-19T12:39:03Z						biological_process											owl:Class	
GO:2000418	biolink:NamedThing	positive regulation of eosinophil migration	Any process that activates or increases the frequency, rate or extent of eosinophil migration.	got7fsn_ti							mah	2011-02-23T01:44:14Z						biological_process											owl:Class	
GO:1901226	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in heart development	OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development.	got7fsn_ti	up regulation of regulation of global transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|upregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|positive regulation of global transcription regulation from Pol II promoter involved in heart development|positive regulation of regulation of global transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|activation of global transcription regulation from Pol II promoter involved in cardiac development|positive regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of global transcription regulation from Pol II promoter involved in cardiac development|upregulation of regulation of transcription from Pol II promoter involved in heart development|up-regulation of global transcription regulation from Pol II promoter involved in heart development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|upregulation of global transcription regulation from Pol II promoter involved in cardiac development|activation of global transcription regulation from Pol II promoter involved in dorsal vessel development|upregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of regulation of global transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of regulation of global transcription from Pol II promoter involved in heart development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|upregulation of global transcription regulation from Pol II promoter involved in heart development|upregulation of regulation of global transcription from Pol II promoter involved in cardiac development|activation of regulation of global transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up-regulation of regulation of global transcription from Pol II promoter involved in heart development|up regulation of regulation of transcription from Pol II promoter involved in cardiac development|positive regulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of regulation of transcription from Pol II promoter involved in heart development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|activation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|upregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|activation of regulation of transcription from Pol II promoter involved in heart development|activation of global transcription regulation from Pol II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of regulation of transcription from Pol II promoter involved in cardiac development|up regulation of global transcription regulation from Pol II promoter involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription regulation from Pol II promoter involved in cardiac development|up-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|positive regulation of regulation of transcription from Pol II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of regulation of transcription from Pol II promoter involved in heart development|upregulation of regulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of global transcription regulation from Pol II promoter involved in heart development|activation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|positive regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|upregulation of regulation of transcription from Pol II promoter involved in cardiac development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of regulation of global transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|upregulation of regulation of global transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|up-regulation of regulation of global transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|activation of regulation of transcription from Pol II promoter involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter involved in heart development				This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0045944|GO:0007507	rl	2012-08-07T07:04:32Z		True				biological_process											owl:Class	
GO:0032911	biolink:NamedThing	negative regulation of transforming growth factor beta1 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.	got7fsn_ti	negative regulation of TGF-B1 production|negative regulation of transforming growth factor-beta1 production|inhibition of transforming growth factor-beta1 production|negative regulation of TGFB1 production|down regulation of transforming growth factor-beta1 production|downregulation of transforming growth factor-beta1 production|down-regulation of transforming growth factor-beta1 production													biological_process											owl:Class	
GO:0051771	biolink:NamedThing	negative regulation of nitric-oxide synthase biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.	got7fsn_ti	inhibition of nitric-oxide synthase biosynthetic process|negative regulation of NOS2 synthase biosynthesis|negative regulation of NOS biosynthesis|down-regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of NO synthase biosynthesis|downregulation of nitric-oxide synthase biosynthetic process|negative regulation of NOS biosynthetic process|negative regulation of NO synthase biosynthetic process|downregulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase (type II) biosynthetic process|negative regulation of NOS2 synthase biosynthetic process|down regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthetic process|down regulation of nitric-oxide synthase biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthesis|down-regulation of nitric-oxide synthase biosynthetic process|inhibition of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase (type II) biosynthesis|negative regulation of nitric-oxide synthase 2 biosynthetic process										GO:0051774			biological_process											owl:Class	
GO:0015023	biolink:NamedThing	obsolete syndecan	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	syndecan				This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0046706	biolink:NamedThing	CDP catabolic process	The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.	got7fsn_ti	CDP catabolism|CDP degradation|CDP breakdown													biological_process											owl:Class	
GO:1900396	biolink:NamedThing	positive regulation of kojic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process.	got7fsn_ti	upregulation of C6H6O4 anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up-regulation of C6H6O4 biosynthesis|activation of C6H6O4 anabolism|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|upregulation of C6H6O4 formation|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of C6H6O4 synthesis|upregulation of C6H6O4 biosynthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up-regulation of kojic acid formation|up regulation of C6H6O4 biosynthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|positive regulation of C6H6O4 anabolism|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of C6H6O4 biosynthetic process|up regulation of C6H6O4 anabolism|up regulation of kojic acid biosynthesis|activation of kojic acid biosynthetic process|activation of C6H6O4 biosynthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|activation of kojic acid synthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|positive regulation of kojic acid anabolism|up regulation of kojic acid biosynthetic process|positive regulation of C6H6O4 biosynthetic process|up regulation of kojic acid anabolism|up regulation of kojic acid synthesis|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|positive regulation of C6H6O4 formation|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|positive regulation of kojic acid formation|up-regulation of kojic acid synthesis|activation of C6H6O4 biosynthetic process|upregulation of kojic acid synthesis|upregulation of kojic acid biosynthesis|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|positive regulation of kojic acid synthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|activation of C6H6O4 formation|up regulation of C6H6O4 biosynthetic process|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|activation of kojic acid biosynthesis|up-regulation of C6H6O4 biosynthetic process|positive regulation of C6H6O4 biosynthesis|up-regulation of C6H6O4 anabolism|activation of kojic acid formation|up-regulation of kojic acid anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up-regulation of kojic acid biosynthetic process|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|up regulation of C6H6O4 formation|positive regulation of kojic acid biosynthesis|activation of C6H6O4 synthesis|up-regulation of kojic acid biosynthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|activation of kojic acid anabolism|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|positive regulation of C6H6O4 synthesis|upregulation of kojic acid formation|upregulation of kojic acid biosynthetic process|up-regulation of C6H6O4 formation|up regulation of C6H6O4 synthesis|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|up-regulation of C6H6O4 synthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|upregulation of kojic acid anabolism|up regulation of kojic acid formation						di	2012-04-18T04:20:11Z						biological_process											owl:Class	
GO:1901895	biolink:NamedThing	negative regulation of ATPase-coupled calcium transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of an  ATPase-coupled calcium transmembrane transporter activity.	got7fsn_ti	down-regulation of Ca(2+)-transporting ATPase activity|down regulation of Ca2+-transporting ATPase activity|downregulation of calcium ABC transporter|negative regulation of Ca2+-transporting ATPase activity|down regulation of plasma membrane Ca-ATPase|downregulation of sarco(endo)plasmic reticulum Ca2+-ATPase|inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase|downregulation of calcium efflux ATPase|inhibition of calcium ABC transporter|negative regulation of calcium pump|down-regulation of calcium transporting ATPase activity|inhibition of Ca2+-pumping ATPase activity|negative regulation of calcium ABC transporter|down regulation of ATP phosphohydrolase (Ca2+-transporting)|down regulation of Ca(2+)-transporting ATPase activity|down regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|downregulation of ATP phosphohydrolase (Ca2+-transporting)|negative regulation of calcium-translocating P-type ATPase activity|negative regulation of calcium transporting ATPase activity|downregulation of plasma membrane Ca-ATPase|downregulation of Ca2+-pumping ATPase activity|inhibition of Ca(2+)-transporting ATPase activity|down regulation of calcium pump|negative regulation of Ca2+-pumping ATPase activity|down regulation of calcium-translocating P-type ATPase activity|inhibition of calcium-transporting ATPase activity|negative regulation of calcium efflux ATPase|downregulation of calcium transporting ATPase activity|down regulation of calcium transporting ATPase activity|down-regulation of Ca2+-pumping ATPase activity|down regulation of Ca2+-pumping ATPase activity|down-regulation of calcium-transporting ATPase activity|inhibition of calcium transporting ATPase activity|inhibition of sarcoplasmic reticulum ATPase|inhibition of plasma membrane Ca-ATPase|negative regulation of plasma membrane Ca-ATPase|down regulation of sarcoplasmic reticulum ATPase|inhibition of calcium pump|down regulation of calcium efflux ATPase|down-regulation of calcium efflux ATPase|down regulation of calcium-transporting ATPase activity|down-regulation of Ca2+-transporting ATPase activity|inhibition of calcium efflux ATPase|inhibition of ATP phosphohydrolase (Ca2+-transporting)|downregulation of Ca(2+)-transporting ATPase activity|down-regulation of calcium-translocating P-type ATPase activity|downregulation of calcium pump|inhibition of Ca2+-transporting ATPase activity|negative regulation of Ca(2+)-transporting ATPase activity|inhibition of calcium-translocating P-type ATPase activity|downregulation of sarcoplasmic reticulum ATPase|down-regulation of calcium ABC transporter|downregulation of calcium-transporting ATPase activity|negative regulation of sarcoplasmic reticulum ATPase|down-regulation of ATP phosphohydrolase (Ca2+-transporting)|negative regulation of calcium-transporting ATPase activity|down-regulation of calcium pump|downregulation of Ca2+-transporting ATPase activity|negative regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|down-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|down-regulation of plasma membrane Ca-ATPase|downregulation of calcium-translocating P-type ATPase activity|down-regulation of sarcoplasmic reticulum ATPase|down regulation of calcium ABC transporter|negative regulation of ATP phosphohydrolase (Ca2+-transporting)						rl	2013-02-06T21:18:25Z						biological_process											owl:Class	
GO:0010843	biolink:NamedThing	obsolete promoter binding	OBSOLETE. Binding to a regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery.	got7fsn_ti	promoter binding|DNA binding, transcription promoter				This term was made obsolete because the word "promoter" is used ambiguously in the literature. It sometimes is used to refer specifically to the "core promoter" region recognized by the basal transcription machinery, and other times is used to refer to a larger regulatory region composed of the core promoter and also the regulatory region adjacent (proximal) to the core promoter. The core promoter proximal region is typically recognized by "regulatory transcription factors", such as Gal4 in S. cerevisiae.	GO:0001046|GO:0000976				True				molecular_function											owl:Class	
GO:0032742	biolink:NamedThing	positive regulation of interleukin-19 production	Any process that activates or increases the frequency, rate, or extent of interleukin-19 production.	got7fsn_ti	positive regulation of interleukin-19 biosynthetic process|upregulation of interleukin-19 production|up regulation of interleukin-19 production|positive regulation of IL-19 production|stimulation of interleukin-19 production|activation of interleukin-19 production|up-regulation of interleukin-19 production										GO:0045386			biological_process											owl:Class	
GO:0035959	biolink:NamedThing	obsolete positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the glyoxylate cycle by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of glyoxylate bypass by positive regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by up regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by up-regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by positive regulation of transcription from Pol II promoter|positive regulation of glyoxylate cycle by up regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by positive regulation of transcription from Pol II promoter|positive regulation of glyoxylate bypass by up-regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by upregulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by stimulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by activation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by upregulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:1905510	biolink:NamedThing	negative regulation of myosin II filament assembly	Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly.	got7fsn_ti	downregulation of myosin II filament assembly|inhibition of myosin II filament assembly|down-regulation of myosin II polymerization|inhibition of myosin II polymerization|down regulation of myosin II filament assembly|down regulation of myosin II polymerization|downregulation of myosin II polymerization|down-regulation of myosin II filament assembly|negative regulation of myosin II polymerization				positive regulation / down regulation of the formation of a bipolar filament composed of myosin II molecules		pf	2016-09-28T13:47:56Z						biological_process											owl:Class	
GO:1905125	biolink:NamedThing	positive regulation of glucosylceramidase activity	Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity.	got7fsn_ti	activation of ceramide glucosidase activity|up-regulation of beta-D-glucocerebrosidase activity|up regulation of ceramide glucosidase activity|positive regulation of psychosine hydrolase activity|positive regulation of acid beta-glucosidase activity|up-regulation of glucosylceramidase activity|up-regulation of acid beta-glucosidase activity|up regulation of GlcCer-beta-glucosidase activity|up-regulation of psychosine hydrolase activity|activation of beta-glucosylceramidase activity|positive regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|positive regulation of GlcCer-beta-glucosidase activity|upregulation of ceramide glucosidase activity|positive regulation of GCase activity|positive regulation of glucosphingosine glucosylhydrolase activity|positive regulation of ceramide glucosidase activity|upregulation of glucosylsphingosine beta-glucosidase activity|positive regulation of beta-glucosylceramidase activity|up-regulation of ceramide glucosidase activity|up regulation of acid beta-glucosidase activity|upregulation of glucosylceramidase activity|positive regulation of glucosylsphingosine beta-D-glucosidase activity|up regulation of beta-glucosylceramidase activity|activation of glucosylsphingosine beta-D-glucosidase activity|upregulation of glucosphingosine glucosylhydrolase activity|up-regulation of glucosylsphingosine beta-D-glucosidase activity|upregulation of beta-glucocerebrosidase activity|up-regulation of glucosylcerebrosidase activity|activation of GlcCer-beta-glucosidase activity|activation of acid beta-glucosidase activity|positive regulation of beta-glucocerebrosidase activity|activation of beta-glucocerebrosidase activity|up regulation of glucosylsphingosine beta-glucosidase activity|up regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up-regulation of glucocerebrosidase activity|positive regulation of glucosylcerebrosidase activity|up-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up regulation of glucosylceramidase activity|up regulation of glucosylcerebrosidase activity|upregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up-regulation of glucosphingosine glucosylhydrolase activity|upregulation of glucocerebrosidase activity|activation of beta-D-glucocerebrosidase activity|positive regulation of beta-D-glucocerebrosidase activity|up-regulation of GlcCer-beta-glucosidase activity|up regulation of beta-D-glucocerebrosidase activity|up regulation of glucosylsphingosine beta-D-glucosidase activity|activation of glucosylceramidase activity|up-regulation of beta-glucocerebrosidase activity|upregulation of glucosylcerebrosidase activity|up regulation of glucosphingosine glucosylhydrolase activity|activation of D-glucosyl-N-acylsphingosine glucohydrolase activity|upregulation of glucosylsphingosine beta-D-glucosidase activity|upregulation of beta-D-glucocerebrosidase activity|up regulation of glucocerebrosidase activity|up-regulation of glucosylsphingosine beta-glucosidase activity|activation of glucosylsphingosine beta-glucosidase activity|up regulation of beta-glucocerebrosidase activity|activation of psychosine hydrolase activity|activation of glucocerebrosidase activity|positive regulation of glucosylsphingosine beta-glucosidase activity|activation of glucosylcerebrosidase activity|upregulation of beta-glucosylceramidase activity|up-regulation of beta-glucosylceramidase activity|upregulation of GlcCer-beta-glucosidase activity|upregulation of psychosine hydrolase activity|positive regulation of glucocerebrosidase activity|upregulation of acid beta-glucosidase activity|up regulation of psychosine hydrolase activity|activation of glucosphingosine glucosylhydrolase activity						bf	2016-04-11T15:44:43Z						biological_process											owl:Class	
GO:0090284	biolink:NamedThing	positive regulation of protein glycosylation in Golgi	Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.	got7fsn_ti	positive regulation of protein amino acid glycosylation in Golgi						tb	2010-02-18T02:43:55Z						biological_process											owl:Class	
GO:1902068	biolink:NamedThing	regulation of sphingolipid mediated signaling pathway	Any process that modulates the frequency, rate or extent of sphingolipid signaling.	got7fsn_ti	regulation of sphingolipid signaling pathway						bf	2013-04-18T13:24:47Z						biological_process											owl:Class	
GO:1903927	biolink:NamedThing	response to cyanide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.	got7fsn_ti							sl	2015-02-11T19:04:19Z						biological_process											owl:Class	
GO:0030211	biolink:NamedThing	heparin catabolic process	The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.	got7fsn_ti	heparin degradation|heparin catabolism|heparin breakdown|heparan sulfate catabolic process													biological_process											owl:Class	
GO:0046243	biolink:NamedThing	obsolete p-xylene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	p-xylene synthesis|para-xylene biosynthesis|p-xylene biosynthesis|p-xylene anabolism|para-xylene biosynthetic process|p-xylene biosynthetic process|p-xylene formation			GO:0018951	This term was made obsolete because p-xylene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0050932	biolink:NamedThing	regulation of pigment cell differentiation	Any process that modulates the frequency, rate or extent of pigmented cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0010748	biolink:NamedThing	negative regulation of long-chain fatty acid import across plasma membrane	Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.	got7fsn_ti	negative regulation of plasma membrane long-chain fatty acid transport													biological_process											owl:Class	
GO:1905840	biolink:NamedThing	positive regulation of telomeric D-loop disassembly	Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly.	got7fsn_ti	activation of telomeric D-loop disassembly|up-regulation of telomeric D-loop disassembly|up regulation of telomeric D-loop disassembly|upregulation of telomeric D-loop disassembly						nc	2017-01-18T11:01:55Z						biological_process											owl:Class	
GO:1901095	biolink:NamedThing	positive regulation of protein homotetramerization	Any process that activates or increases the frequency, rate or extent of protein homotetramerization.	got7fsn_ti	up-regulation of protein homotetramer biosynthesis|activation of protein homotetramer assembly|positive regulation of protein homotetramer biosynthesis|up-regulation of protein homotetramer biosynthetic process|up-regulation of protein homotetramer formation|positive regulation of protein homotetramer biosynthetic process|up regulation of protein homotetramer formation|upregulation of protein homotetramer formation|up regulation of protein homotetramer biosynthesis|activation of protein homotetramer biosynthesis|up-regulation of protein homotetramer assembly|activation of protein homotetramerization|upregulation of protein homotetramer assembly|up regulation of protein homotetramerization|upregulation of protein homotetramer biosynthetic process|activation of protein homotetramer formation|up regulation of protein homotetramer assembly|upregulation of protein homotetramer biosynthesis|positive regulation of protein homotetramer formation|positive regulation of protein homotetramer assembly|activation of protein homotetramer biosynthetic process|up regulation of protein homotetramer biosynthetic process|up-regulation of protein homotetramerization|upregulation of protein homotetramerization						pm	2012-07-06T12:58:06Z						biological_process											owl:Class	
GO:0072350	biolink:NamedThing	tricarboxylic acid metabolic process	The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).	got7fsn_ti	tricarboxylic acid metabolism						mah	2010-11-11T05:07:30Z						biological_process											owl:Class	
GO:0035008	biolink:NamedThing	positive regulation of melanization defense response	Any process that increases the rate or extent of the melanization defense response during injury or invasion.	got7fsn_ti	positive regulation of melanization defence response|upregulation of melanization defense response|stimulation of melanization defense response|up-regulation of melanization defense response|up regulation of melanization defense response|activation of melanization defense response													biological_process											owl:Class	
GO:0052016	biolink:NamedThing	obsolete catabolism by symbiont of host glucan	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of host glucan	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0090389	biolink:NamedThing	phagosome-lysosome fusion involved in apoptotic cell clearance	The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance.	got7fsn_ti							tb	2010-10-27T10:57:39Z						biological_process											owl:Class	
GO:0052396	biolink:NamedThing	obsolete induction by organism of symbiont non-apoptotic programmed cell death	OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of symbiont non-apoptotic programmed cell death|activation by organism of symbiont non-apoptotic programmed cell death				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0018988	biolink:NamedThing	obsolete molting cycle, protein-based cuticle	OBSOLETE. The periodic shedding of part or all of a protein-based cuticle, which is then replaced by a new protein-based cuticle. A cuticle is the outer layer of an animal which acts to prevent water loss.	got7fsn_ti	protein-based cuticle molting cycle				This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0007591|GO:0018996				True				biological_process											owl:Class	
GO:0009192	biolink:NamedThing	deoxyribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	deoxyribonucleoside diphosphate degradation|deoxyribonucleoside diphosphate catabolism|deoxyribonucleoside diphosphate breakdown													biological_process											owl:Class	
GO:0070541	biolink:NamedThing	response to platinum ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.	got7fsn_ti	response to platinum													biological_process											owl:Class	
GO:2000080	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.	got7fsn_ti	negative regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|negative regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|negative regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation						tb	2010-08-27T11:22:58Z						biological_process											owl:Class	
CHEBI:64474	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048386	biolink:NamedThing	positive regulation of retinoic acid receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.	got7fsn_ti	upregulation of retinoic acid receptor signaling pathway|up-regulation of retinoic acid receptor signaling pathway|stimulation of retinoic acid receptor signaling pathway|up regulation of retinoic acid receptor signaling pathway|activation of retinoic acid receptor signaling pathway|positive regulation of RAR signaling pathway|positive regulation of retinoic acid receptor signalling pathway													biological_process											owl:Class	
GO:1902991	biolink:NamedThing	regulation of amyloid precursor protein catabolic process	Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process.	got7fsn_ti	regulation of amyloid precursor protein breakdown|regulation of amyloid precursor protein degradation|regulation of APP catabolism|regulation of APP catabolic process|regulation of amyloid precursor protein catabolism				An example of this is human FKBP1A/12 (UniProt symbol P62942) in PMID:24499793 (inferred from direct assay).		rl	2014-05-08T14:21:04Z						biological_process											owl:Class	
GO:0015492	biolink:NamedThing	phenylalanine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in).	got7fsn_ti	phenylalanine:hydrogen symporter activity													molecular_function											owl:Class	
GO:0015445	biolink:NamedThing	P-type silver transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) -> ADP + phosphate + Ag+(out).	got7fsn_ti	silver transmembrane transporter activity, phosphorylative mechanism|silver-exporting ATPase activity|ATP phosphohydrolase (Ag+-exporting)|Ag+-exporting ATPase activity|silver exporting ATPase activity											EC:7.2.2.15|MetaCyc:3.6.3.53-RXN|RHEA:14733		molecular_function											owl:Class	
GO:0050763	biolink:NamedThing	depsipeptide biosynthetic process	The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.	got7fsn_ti	depsipeptide anabolism|depsipeptide synthesis|depsipeptide formation|depsipeptide biosynthesis													biological_process											owl:Class	
GO:1902225	biolink:NamedThing	negative regulation of acrosome reaction	Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction.	got7fsn_ti	downregulation of acrosome reaction|down-regulation of acrosome reaction|down regulation of acrosome reaction|inhibition of acrosome reaction						ae	2013-06-13T14:17:11Z						biological_process											owl:Class	
GO:0010903	biolink:NamedThing	negative regulation of very-low-density lipoprotein particle remodeling	Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.	got7fsn_ti	negative regulation of VLDL remodeling													biological_process											owl:Class	
GO:0009082	biolink:NamedThing	branched-chain amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.	got7fsn_ti	branched chain family amino acid biosynthesis|branched chain family amino acid synthesis|branched chain family amino acid biosynthetic process|branched chain family amino acid formation|branched chain family amino acid anabolism													biological_process											owl:Class	
GO:2000439	biolink:NamedThing	positive regulation of monocyte extravasation	Any process that activates or increases the frequency, rate or extent of monocyte extravasation.	got7fsn_ti							bf	2011-03-04T10:25:11Z						biological_process											owl:Class	
GO:1901637	biolink:NamedThing	obsolete positive regulation of maintenance of presynaptic active zone structure	OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of presynaptic active zone structure.	got7fsn_ti	upregulation of maintenance of presynaptic active zone structure|activation of maintenance of presynaptic active zone structure|up regulation of maintenance of presynaptic active zone structure|positive regulation of maintenance of presynaptic active zone structure|up-regulation of maintenance of presynaptic active zone structure				This term was obsoleted at the TermGenie Gatekeeper stage.		ans	2012-11-15T14:17:16Z		True				biological_process											owl:Class	
GO:0030170	biolink:NamedThing	pyridoxal phosphate binding	Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.	got7fsn_ti														molecular_function											owl:Class	
GO:1903560	biolink:NamedThing	3-cyano-L-alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine.	got7fsn_ti	3-cyano-L-alanine biosynthesis|3-cyano-L-alanine formation|3-cyano-L-alanine synthesis|3-cyano-L-alanine anabolism						kmv	2014-10-21T17:13:26Z						biological_process											owl:Class	
GO:1904027	biolink:NamedThing	negative regulation of collagen fibril organization	Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization.	got7fsn_ti	down-regulation of collagen fibril organization|downregulation of fibrillar collagen organization|inhibition of fibrillar collagen organization|inhibition of collagen fibril organisation|down-regulation of collagen fibril organisation|down-regulation of fibrillar collagen organization|down regulation of collagen fibril organization|inhibition of collagen fibril organization|negative regulation of fibrillar collagen organization|down regulation of collagen fibril organisation|negative regulation of collagen fibril organisation|down regulation of fibrillar collagen organization|downregulation of collagen fibril organisation|downregulation of collagen fibril organization						ae	2015-03-12T12:36:59Z						biological_process											owl:Class	
GO:1905576	biolink:NamedThing	ganglioside GT1b binding	Binding to ganglioside GT1b.	got7fsn_ti							pga	2016-10-19T11:17:17Z						molecular_function											owl:Class	
GO:0015063	biolink:NamedThing	obsolete long-wave-sensitive opsin	OBSOLETE. An opsin with maximal absorption above 500 nm.	got7fsn_ti	long-wave-sensitive opsin				This term was made obsolete because it refers to a class of proteins.	GO:0046876|GO:0016021|GO:0007603|GO:0016918|GO:0009881				True				molecular_function											owl:Class	
GO:2001250	biolink:NamedThing	positive regulation of ammonia assimilation cycle	Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle.	got7fsn_ti	positive regulation of glutamate metabolism via glutamine and ammonia|positive regulation of glutamate metabolic process via glutamine and ammonia						rl	2011-12-01T10:08:34Z						biological_process											owl:Class	
GO:1905460	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.	got7fsn_ti	downregulation of vascular associated smooth muscle cell apoptotic process|down-regulation of vascular smooth muscle cell apoptosis|downregulation of VSMC apoptotic process|down regulation of vascular associated smooth muscle cell apoptosis|down regulation of vascular smooth muscle cell apoptosis|down-regulation of vascular smooth muscle cell apoptotic process|down-regulation of vascular associated smooth muscle cell apoptotic process|inhibition of vascular associated smooth muscle cell apoptosis|down-regulation of VSMC apoptosis|inhibition of vascular smooth muscle cell apoptotic process|down regulation of vascular associated smooth muscle cell apoptotic process|downregulation of VSMC apoptosis|downregulation of vascular associated smooth muscle cell apoptosis|downregulation of vascular smooth muscle cell apoptosis|down regulation of vascular smooth muscle cell apoptotic process|negative regulation of VSMC apoptotic process|inhibition of vascular associated smooth muscle cell apoptotic process|down regulation of VSMC apoptosis|inhibition of VSMC apoptotic process|downregulation of vascular smooth muscle cell apoptotic process|down-regulation of VSMC apoptotic process|down-regulation of vascular associated smooth muscle cell apoptosis|negative regulation of VSMC apoptosis|inhibition of VSMC apoptosis|negative regulation of vascular smooth muscle cell apoptosis|negative regulation of vascular smooth muscle cell apoptotic process|down regulation of VSMC apoptotic process|inhibition of vascular smooth muscle cell apoptosis|negative regulation of vascular associated smooth muscle cell apoptosis						rph	2016-09-19T11:34:03Z						biological_process											owl:Class	
GO:0052199	biolink:NamedThing	obsolete negative regulation of catalytic activity in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	downregulation of enzyme activity in other organism during symbiotic interaction|down regulation of enzyme activity in other organism during symbiotic interaction|down-regulation of enzyme activity in other organism during symbiotic interaction|negative regulation of enzyme activity in other organism during symbiotic interaction|inhibition of enzyme activity in other organism|inhibition of enzyme activity in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it was an unnecessary grouping term.					True				biological_process											owl:Class	
GO:0019376	biolink:NamedThing	galactolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.	got7fsn_ti	galactolipid breakdown|galactolipid degradation|galactolipid catabolism													biological_process											owl:Class	
GO:1904229	biolink:NamedThing	regulation of succinate dehydrogenase activity	Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity.	got7fsn_ti	regulation of succinic dehydrogenase activity|regulation of succinate oxidoreductase activity|regulation of succinate:(acceptor) oxidoreductase activity|regulation of fumaric hydrogenase activity|regulation of succinodehydrogenase activity|regulation of fumarate reductase activity|regulation of succinic acid dehydrogenase activity|regulation of fumarate dehydrogenase activity|regulation of succinyl dehydrogenase activity|regulation of succinate:acceptor oxidoreductase activity						rl	2015-05-15T09:51:08Z						biological_process											owl:Class	
GO:0042029	biolink:NamedThing	obsolete fibrolase activity	OBSOLETE. Catalysis of the cleavage of 14-Ala-Leu-15 in insulin B chain and cleavage of 413-Lys-Leu-414 in alpha chain of fibrinogen.	got7fsn_ti	fibrinolytic proteinase activity|Agkistrodon contortrix contortrix metalloproteinase activity|fibrolase activity|Agkistrodon contortrix contortrix venom metalloproteinase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0052531	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont calcium ion flux	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of fluxes of calcium ions that occur as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of defense-related symbiont calcium ion flux|positive regulation by organism of defense-related symbiont Ca2+ flux				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1900092	biolink:NamedThing	negative regulation of raffinose biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process.	got7fsn_ti	down-regulation of raffinose synthesis|down regulation of raffinose formation|inhibition of raffinose synthesis|inhibition of raffinose biosynthesis|down regulation of raffinose biosynthetic process|downregulation of raffinose anabolism|inhibition of raffinose formation|negative regulation of raffinose formation|downregulation of raffinose biosynthetic process|down regulation of raffinose anabolism|negative regulation of raffinose biosynthesis|down-regulation of raffinose biosynthetic process|down-regulation of raffinose formation|downregulation of raffinose synthesis|inhibition of raffinose anabolism|downregulation of raffinose formation|negative regulation of raffinose synthesis|negative regulation of raffinose anabolism|down-regulation of raffinose biosynthesis|down-regulation of raffinose anabolism|down regulation of raffinose biosynthesis|down regulation of raffinose synthesis|downregulation of raffinose biosynthesis|inhibition of raffinose biosynthetic process						dhl	2012-02-08T06:31:58Z						biological_process											owl:Class	
GO:0061396	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0071280	dph	2012-01-10T09:07:08Z		True				biological_process											owl:Class	
GO:0035205	biolink:NamedThing	positive regulation of lamellocyte differentiation	Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.	got7fsn_ti	up regulation of lamellocyte differentiation|stimulation of lamellocyte differentiation|up-regulation of lamellocyte differentiation|upregulation of lamellocyte differentiation|activation of lamellocyte differentiation													biological_process											owl:Class	
GO:0003295	biolink:NamedThing	cell proliferation involved in atrial ventricular junction remodeling	The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.	got7fsn_ti	cell proliferation involved in atrioventricular junction remodeling|cell proliferation involved in atrio-ventricular junction remodeling						dph	2009-10-22T08:38:30Z						biological_process											owl:Class	
GO:1903824	biolink:NamedThing	negative regulation of telomere single strand break repair	Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair.	got7fsn_ti	negative regulation of single strand break repair in telomere|negative regulation of telomere SSBR|inhibition of single strand break repair in telomere|downregulation of telomere single-strand break repair|down regulation of telomere single-strand break repair|down regulation of single strand break repair in telomere|negative regulation of telomere single-strand break repair|inhibition of telomere SSBR|downregulation of telomere SSBR|downregulation of telomeric single strand break repair|negative regulation of telomeric single strand break repair|down-regulation of telomere SSBR|down-regulation of telomeric single strand break repair|down-regulation of telomere single strand break repair|inhibition of telomeric single strand break repair|inhibition of telomere single strand break repair|down-regulation of single strand break repair in telomere|down regulation of telomere SSBR|down regulation of telomere single strand break repair|downregulation of telomere single strand break repair|downregulation of single strand break repair in telomere|inhibition of telomere single-strand break repair|down regulation of telomeric single strand break repair|down-regulation of telomere single-strand break repair						jl	2015-01-19T16:24:37Z						biological_process											owl:Class	
GO:2000885	biolink:NamedThing	galactoglucomannan catabolic process	The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan.	got7fsn_ti	galactoglucomannan catabolism						jl	2011-07-28T09:24:11Z						biological_process											owl:Class	
GO:0031231	biolink:NamedThing	intrinsic component of peroxisomal membrane	The component of the peroxisomal membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to peroxisomal membrane													cellular_component											owl:Class	
GO:0034135	biolink:NamedThing	regulation of toll-like receptor 2 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 2 signalling pathway|regulation of TLR2 signaling pathway													biological_process											owl:Class	
GO:0010947	biolink:NamedThing	negative regulation of meiotic joint molecule formation	Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.	got7fsn_ti							tb	2009-04-27T09:48:53Z						biological_process											owl:Class	
GO:1904755	biolink:NamedThing	regulation of gut granule assembly	Any process that modulates the frequency, rate or extent of gut granule assembly.	got7fsn_ti	regulation of gut granule formation|regulation of gut granule biogenesis						ah	2015-10-21T08:43:44Z						biological_process											owl:Class	
GO:1903177	biolink:NamedThing	negative regulation of tyrosine 3-monooxygenase activity	Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity.	got7fsn_ti	down regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|negative regulation of L-tyrosine hydroxylase activity|downregulation of tyrosine 3-hydroxylase activity|down-regulation of tyrosine 3-hydroxylase activity|negative regulation of tyrosine 3-hydroxylase activity|inhibition of tyrosine hydroxylase activity|down regulation of tyrosine 3-monooxygenase activity|down-regulation of L-tyrosine hydroxylase activity|inhibition of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|downregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|inhibition of tyrosine 3-hydroxylase activity|down-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|downregulation of L-tyrosine hydroxylase activity|down regulation of tyrosine hydroxylase activity|negative regulation of tyrosine hydroxylase activity|down-regulation of tyrosine hydroxylase activity|down regulation of tyrosine 3-hydroxylase activity|inhibition of L-tyrosine hydroxylase activity|down regulation of L-tyrosine hydroxylase activity|negative regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|down-regulation of tyrosine 3-monooxygenase activity|downregulation of tyrosine 3-monooxygenase activity|inhibition of tyrosine 3-monooxygenase activity|downregulation of tyrosine hydroxylase activity						bf	2014-07-14T10:39:15Z						biological_process											owl:Class	
GO:1903997	biolink:NamedThing	positive regulation of non-membrane spanning protein tyrosine kinase activity	Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.	got7fsn_ti	positive regulation of p60c-src protein tyrosine kinase activity|upregulation of p60c-src protein tyrosine kinase activity|up regulation of cytoplasmic protein tyrosine kinase activity|positive regulation of non-specific protein-tyrosine kinase activity|activation of cytoplasmic protein tyrosine kinase activity|positive regulation of janus kinase 3 activity|positive regulation of focal adhesion kinase activity|up-regulation of non-specific protein-tyrosine kinase activity|up-regulation of cytoplasmic protein tyrosine kinase activity|up-regulation of non-membrane spanning protein tyrosine kinase activity|upregulation of non-membrane spanning protein tyrosine kinase activity|activation of non-membrane spanning protein tyrosine kinase activity|upregulation of janus kinase 2 activity|activation of janus kinase 2 activity|up-regulation of Bruton's tyrosine kinase activity|activation of p60c-src protein tyrosine kinase activity|upregulation of janus kinase 1 activity|upregulation of Bruton's tyrosine kinase activity|upregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up-regulation of p60c-src protein tyrosine kinase activity|positive regulation of cytoplasmic protein tyrosine kinase activity|activation of janus kinase 1 activity|up regulation of janus kinase 1 activity|up regulation of non-membrane spanning protein tyrosine kinase activity|positive regulation of janus kinase 1 activity|upregulation of janus kinase 3 activity|activation of focal adhesion kinase activity|up regulation of focal adhesion kinase activity|upregulation of non-specific protein-tyrosine kinase activity|activation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of janus kinase 2 activity|activation of Bruton's tyrosine kinase activity|activation of janus kinase 3 activity|up-regulation of janus kinase 3 activity|up regulation of janus kinase 3 activity|up regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|upregulation of focal adhesion kinase activity|upregulation of cytoplasmic protein tyrosine kinase activity|up-regulation of janus kinase 1 activity|positive regulation of Bruton's tyrosine kinase activity|up regulation of Bruton's tyrosine kinase activity|up-regulation of focal adhesion kinase activity|up-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of p60c-src protein tyrosine kinase activity|activation of non-specific protein-tyrosine kinase activity|positive regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of non-specific protein-tyrosine kinase activity|up-regulation of janus kinase 2 activity|positive regulation of janus kinase 2 activity						nc	2015-03-05T16:34:46Z						biological_process											owl:Class	
CHEBI:30023	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901485	biolink:NamedThing	positive regulation of transcription factor catabolic process	Any process that activates or increases the frequency, rate or extent of transcription factor catabolic process.	got7fsn_ti	upregulation of transcription factor catabolism|up-regulation of proteasome-mediated transcription factor catabolism|positive regulation of sequence-specific DNA binding transcription factor catabolic process|up-regulation of transcription factor breakdown|up regulation of proteasome-mediated transcription factor catabolism|up regulation of transcription factor degradation|upregulation of transcription factor breakdown|up-regulation of transcription factor degradation|up regulation of transcription factor catabolic process|up-regulation of sequence-specific DNA binding transcription factor catabolic process|positive regulation of transcription factor degradation|positive regulation of transcription factor breakdown|upregulation of sequence-specific DNA binding transcription factor catabolic process|activation of transcription factor degradation|up-regulation of transcription factor catabolic process|up regulation of sequence-specific DNA binding transcription factor catabolic process|upregulation of transcription factor catabolic process|up-regulation of transcription factor catabolism|activation of sequence-specific DNA binding transcription factor catabolic process|upregulation of transcription factor degradation|up regulation of transcription factor catabolism|activation of proteasome-mediated transcription factor catabolism|upregulation of proteasome-mediated transcription factor catabolism|activation of transcription factor breakdown|positive regulation of transcription factor catabolism|activation of transcription factor catabolism|up regulation of transcription factor breakdown|positive regulation of proteasome-mediated transcription factor catabolism|activation of transcription factor catabolic process						bf	2012-10-08T09:03:27Z						biological_process											owl:Class	
GO:1903747	biolink:NamedThing	regulation of establishment of protein localization to mitochondrion	Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion.	got7fsn_ti	regulation of establishment of protein localisation to mitochondrion|regulation of establishment of protein localization in mitochondrion						krc	2014-12-12T22:18:09Z						biological_process											owl:Class	
GO:0052208	biolink:NamedThing	obsolete modification of morphology or physiology of other organism via substance secreted by type IV secretion system involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type IV secretion system in the first organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modification of morphology or physiology of other organism via substance secreted by type IV secretion system during symbiotic interaction				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0030484	biolink:NamedThing	obsolete muscle fiber	OBSOLETE. The contractile fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.	got7fsn_ti	muscle fiber|muscle fibre				This term was made obsolete because a muscle fiber is a cell type rather than a cell component. To update annotations, consider the external ontology term 'muscle cell ; CL:0000187'.	GO:0043292				True				cellular_component											owl:Class	
GO:1904707	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell proliferation	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.	got7fsn_ti	positive regulation of VSMC proliferation|positive regulation of vascular smooth muscle cell proliferation|upregulation of vascular smooth muscle cell proliferation|up regulation of vascular smooth muscle cell proliferation|up regulation of VSMC proliferation|activation of vascular smooth muscle cell proliferation|upregulation of VSMC proliferation|activation of VSMC proliferation|up-regulation of vascular smooth muscle cell proliferation|up-regulation of VSMC proliferation						sl	2015-10-01T16:05:32Z						biological_process											owl:Class	
GO:1900715	biolink:NamedThing	positive regulation of violaceol I biosynthetic process	Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process.	got7fsn_ti	upregulation of violaceol I synthesis|up regulation of violaceol I biosynthesis|positive regulation of violaceol I biosynthesis|activation of violaceol I formation|positive regulation of violaceol I formation|up regulation of violaceol I synthesis|up regulation of violaceol I biosynthetic process|upregulation of violaceol I biosynthetic process|up regulation of violaceol I formation|positive regulation of violaceol I anabolism|activation of violaceol I synthesis|upregulation of violaceol I anabolism|upregulation of violaceol I formation|up-regulation of violaceol I synthesis|up-regulation of violaceol I biosynthetic process|up-regulation of violaceol I formation|activation of violaceol I anabolism|up regulation of violaceol I anabolism|upregulation of violaceol I biosynthesis|activation of violaceol I biosynthesis|positive regulation of violaceol I synthesis|up-regulation of violaceol I biosynthesis|activation of violaceol I biosynthetic process|up-regulation of violaceol I anabolism						di	2012-05-22T05:04:41Z						biological_process											owl:Class	
GO:0005071	biolink:NamedThing	obsolete transmembrane receptor protein serine/threonine kinase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transmembrane receptor protein serine/threonine kinase signalling protein activity|transmembrane receptor protein serine/threonine kinase signaling protein activity				This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556|GO:0007178				True				molecular_function											owl:Class	
GO:0004295	biolink:NamedThing	obsolete trypsin activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa.	got7fsn_ti	parenzyme|alpha-trypsin activity|trypsin activity|cocoonase activity|trypure|tryptar|pseudotrypsin|tripcellim|sperm receptor hydrolase activity|beta-trypsin activity|parenzymol			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1990419	biolink:NamedThing	obsolete response to elemental metal	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an elemental metal stimulus.	got7fsn_ti	response to elemental metal				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-07-15T20:17:56Z		True				biological_process											owl:Class	
GO:1902836	biolink:NamedThing	positive regulation of proline import across plasma membrane	Any process that activates or increases the frequency, rate or extent of proline import into cell.	got7fsn_ti	up regulation of proline import into cell|activation of proline import into cell|up-regulation of proline import into cell|upregulation of proline import into cell|positive regulation of proline import into cell						mah	2014-04-01T13:44:20Z						biological_process											owl:Class	
GO:0075158	biolink:NamedThing	obsolete negative regulation of G protein-coupled receptor signaling pathway in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|negative regulation of G-protein coupled receptor protein signaling pathway in response to host|negative regulation of G-protein coupled receptor protein signalling pathway in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0005762	biolink:NamedThing	mitochondrial large ribosomal subunit	The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).	got7fsn_ti	39S ribosomal subunit, mitochondrial													cellular_component											owl:Class	
GO:0043372	biolink:NamedThing	positive regulation of CD4-positive, alpha-beta T cell differentiation	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.	got7fsn_ti	positive regulation of CD4-positive T-lymphocyte differentiation|positive regulation of CD4-positive T lymphocyte differentiation|positive regulation of CD4-positive, alpha beta T cell differentiation|stimulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T-cell differentiation|positive regulation of CD4-positive T-cell differentiation|positive regulation of CD4-positive, alpha beta T lymphocyte differentiation|upregulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T-lymphocyte differentiation|activation of CD4-positive, alpha beta T cell differentiation|up regulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T cell development|up-regulation of CD4-positive, alpha beta T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1902904	biolink:NamedThing	negative regulation of supramolecular fiber organization	Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.	got7fsn_ti	downregulation of fibril organisation|inhibition of fibril organisation|downregulation of fibril organization|down regulation of fibril organization|negative regulation of fibril organisation|inhibition of fibril organization|down-regulation of fibril organization|down regulation of fibril organisation|down-regulation of fibril organisation				HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro		rl	2014-04-15T16:46:42Z						biological_process											owl:Class	
GO:1905596	biolink:NamedThing	negative regulation of low-density lipoprotein particle receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding.	got7fsn_ti	negative regulation of LDL receptor binding|down regulation of LDL receptor binding|inhibition of LDL receptor binding|inhibition of low-density lipoprotein receptor binding|down regulation of low-density lipoprotein particle receptor binding|down-regulation of low-density lipoprotein particle receptor binding|downregulation of LDL receptor binding|down-regulation of LDL receptor binding|down-regulation of low-density lipoprotein receptor binding|negative regulation of low-density lipoprotein receptor binding|downregulation of low-density lipoprotein receptor binding|inhibition of low-density lipoprotein particle receptor binding|down regulation of low-density lipoprotein receptor binding|downregulation of low-density lipoprotein particle receptor binding						nc	2016-10-26T10:57:31Z						biological_process											owl:Class	
GO:0010722	biolink:NamedThing	regulation of ferrochelatase activity	Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.	got7fsn_ti														biological_process											owl:Class	
GO:0072097	biolink:NamedThing	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor resulting in the reduction of the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.	got7fsn_ti	negative regulation of branch elongation involved in ureteric bud branching by BMP signalling pathway						mah	2010-02-10T02:00:34Z						biological_process											owl:Class	
GO:2001294	biolink:NamedThing	malonyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A.	got7fsn_ti	malonyl-CoA degradation|malonyl-CoA breakdown|malonyl-CoA catabolism						pr	2012-02-14T02:23:17Z						biological_process											owl:Class	
GO:0019407	biolink:NamedThing	hexitol catabolic process	The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.	got7fsn_ti	hexitol breakdown|hexitol degradation|hexitol catabolism													biological_process											owl:Class	
GO:0071640	biolink:NamedThing	regulation of macrophage inflammatory protein 1 alpha production	Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.	got7fsn_ti	regulation of MIP-1a production|regulation of CCL3 production|regulation of macrophage inflammatory protein production|regulation of chemokine (C-C motif) ligand 3 production						mah	2010-02-12T10:39:51Z						biological_process											owl:Class	
GO:0009184	biolink:NamedThing	purine deoxyribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside diphosphate degradation|purine deoxyribonucleoside diphosphate catabolism|purine deoxyribonucleoside diphosphate breakdown													biological_process											owl:Class	
GO:1904225	biolink:NamedThing	positive regulation of glucuronosyltransferase activity	Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity.	got7fsn_ti	up-regulation of estrone UDPglucuronosyltransferase activity|positive regulation of p-nitrophenylglucuronosyltransferase activity|upregulation of 3-OH androgenic UDPGT activity|up regulation of UDP glucuronate-estriol glucuronosyltransferase activity|up-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of UDP glucuronate-estriol glucuronosyltransferase activity|positive regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of 1-naphthol glucuronyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|up-regulation of uridine diphosphate glucuronyltransferase activity|up regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of UDPGA transferase activity|upregulation of UDP glucuronosyltransferase activity|up-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|positive regulation of UDP glucuronosyltransferase activity|positive regulation of 17-OH steroid UDPGT activity|up-regulation of 4-nitrophenol UDPGT activity|upregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronosyltransferase activity|positive regulation of p-nitrophenol UDP-glucuronyltransferase activity|activation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of 1-naphthol-UDP-glucuronosyltransferase activity|activation of UDP glucuronate-estradiol-glucuronosyltransferase activity|up regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of 4-nitrophenol UDPGT activity|up-regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up-regulation of morphine glucuronyltransferase activity|up-regulation of GT activity|up regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|activation of uridine 5'-diphosphoglucuronyltransferase activity|positive regulation of UDPGT activity|upregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up regulation of UDP-glucuronyltransferase activity|up regulation of morphine glucuronyltransferase activity|upregulation of estriol UDPglucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|up regulation of estrone UDPglucuronosyltransferase activity|positive regulation of ciramadol UDP-glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|up-regulation of glucuronosyltransferase activity|positive regulation of bilirubin monoglucuronide glucuronyltransferase activity|activation of pnp-UDPGT activity|positive regulation of UDP-glucuronyltransferase activity|upregulation of uridine diphosphate glucuronyltransferase activity|up regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|up-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of UDPGA-glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|activation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up regulation of uridine diphosphoglucuronyltransferase activity|upregulation of p-nitrophenol UDP-glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|positive regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|positive regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|upregulation of glucuronosyltransferase activity|positive regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|upregulation of bilirubin glucuronyltransferase activity|upregulation of GT activity|upregulation of UDPGT activity|up regulation of p-phenylphenol glucuronyltransferase activity|positive regulation of uridine diphosphate glucuronyltransferase activity|positive regulation of uridine 5'-diphosphoglucuronyltransferase activity|activation of PNP-UDPGT|up-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|upregulation of p-phenylphenol glucuronyltransferase activity|upregulation of bilirubin uridine diphosphoglucuronyltransferase activity|positive regulation of estriol UDPglucuronosyltransferase activity|upregulation of p-nitrophenylglucuronosyltransferase activity|activation of bilirubin glucuronyltransferase activity|up regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronyltransferase activity|up-regulation of bilirubin UDP-glucuronosyltransferase activity|up-regulation of p-nitrophenol UDP-glucuronosyltransferase activity|positive regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|up regulation of bilirubin uridine diphosphoglucuronyltransferase activity|upregulation of 1-naphthol glucuronyltransferase activity|up-regulation of pnp-UDPGT activity|activation of morphine glucuronyltransferase activity|upregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronyltransferase activity|activation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up regulation of 3-OH androgenic UDPGT activity|positive regulation of estrone UDPglucuronosyltransferase activity|activation of 1-naphthol glucuronyltransferase activity|up regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of p-phenylphenol glucuronyltransferase activity|activation of UDPGT activity|activation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up-regulation of phenyl-UDP-glucuronosyltransferase activity|upregulation of estrone UDPglucuronosyltransferase activity|activation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of 3-OH androgenic UDPGT activity|upregulation of uridine diphosphoglucuronyltransferase activity|up regulation of bilirubin monoglucuronide glucuronyltransferase activity|activation of 3-OH androgenic UDPGT activity|up-regulation of bilirubin monoglucuronide glucuronyltransferase activity|activation of uridine diphosphoglucuronyltransferase activity|up-regulation of UDP glucuronyltransferase activity|up regulation of uridine diphosphate glucuronyltransferase activity|up-regulation of UDP-glucuronosyltransferase activity|positive regulation of pnp-UDPGT activity|upregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of 17-OH steroid UDPGT activity|upregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|positive regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of UDPGA transferase activity|activation of 4-nitrophenol UDPGT activity|upregulation of p-nitrophenol UDP-glucuronosyltransferase activity|up regulation of GT activity|activation of estrone UDPglucuronosyltransferase activity|positive regulation of bilirubin UDPGT activity|activation of UDPGA transferase activity|activation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of UDP glucuronyltransferase activity|up regulation of UDP glucuronyltransferase activity|activation of UDPGA-glucuronyltransferase activity|up regulation of p-nitrophenol UDP-glucuronosyltransferase activity|activation of GT activity|up regulation of UDP-glucuronosyltransferase activity|activation of UDP-glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|up regulation of bilirubin glucuronyltransferase activity|up regulation of uridine 5'-diphosphoglucuronyltransferase activity|activation of bilirubin uridine diphosphoglucuronyltransferase activity|up-regulation of bilirubin glucuronyltransferase activity|upregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|positive regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of phenyl-UDP-glucuronosyltransferase activity|positive regulation of p-phenylphenol glucuronyltransferase activity|activation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of bilirubin monoglucuronide glucuronyltransferase activity|up regulation of ciramadol UDP-glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|upregulation of UDPGA-glucuronyltransferase activity|upregulation of uridine 5'-diphosphoglucuronyltransferase activity|activation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|positive regulation of p-nitrophenol UDP-glucuronosyltransferase activity|upregulation of bilirubin UDP-glucuronosyltransferase activity|up regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|positive regulation of PNP-UDPGT|activation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up-regulation of 3-OH androgenic UDPGT activity|up-regulation of UDP glucuronosyltransferase activity|up regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|upregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up regulation of phenyl-UDP-glucuronosyltransferase activity|up-regulation of 17-OH steroid UDPGT activity|activation of p-nitrophenol UDP-glucuronosyltransferase activity|up-regulation of UDPGT activity|up regulation of PNP-UDPGT|upregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|activation of ciramadol UDP-glucuronyltransferase activity|upregulation of UDP glucuronyltransferase activity|upregulation of PNP-UDPGT|activation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|positive regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|positive regulation of morphine glucuronyltransferase activity|activation of 1-naphthol-UDP-glucuronosyltransferase activity|positive regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of p-nitrophenylglucuronosyltransferase activity|up regulation of UDP glucuronic acid transferase activity|positive regulation of 1-naphthol glucuronyltransferase activity|upregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|up-regulation of UDP glucuronic acid transferase activity|up regulation of p-nitrophenylglucuronosyltransferase activity|positive regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|positive regulation of 4-nitrophenol UDP-glucuronyltransferase activity|up regulation of UDPGT activity|positive regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|up regulation of bilirubin UDP-glucuronosyltransferase activity|activation of uridine diphosphoglucuronosyltransferase activity|up-regulation of 1-naphthol glucuronyltransferase activity|up regulation of 4-nitrophenol UDP-glucuronyltransferase activity|upregulation of 1-naphthol-UDP-glucuronosyltransferase activity|up-regulation of UDP glucuronate-estriol glucuronosyltransferase activity|positive regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of p-nitrophenol UDP-glucuronyltransferase activity|upregulation of morphine glucuronyltransferase activity|up regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|positive regulation of UDP glucuronyltransferase activity|upregulation of ciramadol UDP-glucuronyltransferase activity|positive regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of estriol UDPglucuronosyltransferase activity|upregulation of 17-OH steroid UDPGT activity|upregulation of 4-nitrophenol UDPGT activity|activation of UDP-glucuronyltransferase activity|up-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up-regulation of uridine diphosphoglucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|activation of bilirubin UDPGT activity|up regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|up-regulation of PNP-UDPGT|upregulation of uridine diphosphoglucuronosyltransferase activity|up-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|activation of 4-nitrophenol UDP-glucuronyltransferase activity|up-regulation of 4-nitrophenol UDP-glucuronyltransferase activity|up regulation of glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|positive regulation of bilirubin glucuronyltransferase activity|activation of UDP glucuronosyltransferase activity|up regulation of UDPGA transferase activity|positive regulation of 4-nitrophenol UDPGT activity|up-regulation of UDP-glucuronyltransferase activity|up-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|positive regulation of UDP-glucuronosyltransferase activity|up regulation of bilirubin UDPGT activity|upregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|positive regulation of GT activity|upregulation of UDP-glucuronosyltransferase activity|up regulation of pnp-UDPGT activity|upregulation of 4-nitrophenol UDP-glucuronyltransferase activity|activation of uridine diphosphate glucuronyltransferase activity|upregulation of bilirubin UDPGT activity|up-regulation of p-nitrophenol UDP-glucuronyltransferase activity|activation of bilirubin UDP-glucuronosyltransferase activity|activation of UDP glucuronic acid transferase activity|activation of glucuronosyltransferase activity|up-regulation of uridine 5'-diphosphoglucuronyltransferase activity|positive regulation of UDP glucuronic acid transferase activity|positive regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up regulation of estriol UDPglucuronosyltransferase activity|activation of p-nitrophenol UDP-glucuronyltransferase activity|up-regulation of estriol UDPglucuronosyltransferase activity|activation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|activation of UDP-glucuronate-bilirubin glucuronyltransferase activity|up-regulation of bilirubin UDPGT activity|upregulation of phenyl-UDP-glucuronosyltransferase activity|positive regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up regulation of 1-naphthol-UDP-glucuronosyltransferase activity|upregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|upregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of p-phenylphenol glucuronyltransferase activity|activation of UDP glucuronate-estriol glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of bilirubin UDP-glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|up-regulation of UDPGA transferase activity|up-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up regulation of UDP glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|up-regulation of 1-naphthol-UDP-glucuronosyltransferase activity|up regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|upregulation of UDP glucuronic acid transferase activity|upregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|upregulation of UDP-glucuronyltransferase activity|up-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up regulation of uridine diphosphoglucuronosyltransferase activity|upregulation of UDP glucuronate-estriol glucuronosyltransferase activity|up-regulation of ciramadol UDP-glucuronyltransferase activity|activation of p-nitrophenylglucuronosyltransferase activity|upregulation of bilirubin monoglucuronide glucuronyltransferase activity|up-regulation of UDPGA-glucuronyltransferase activity|activation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|positive regulation of UDPGA-glucuronyltransferase activity|upregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|upregulation of pnp-UDPGT activity|activation of 17-OH steroid UDPGT activity|upregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of phenyl-UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity				i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species		rl	2015-05-15T08:44:32Z						biological_process											owl:Class	
GO:1903916	biolink:NamedThing	regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.	got7fsn_ti	regulation of eIF2alpha dephosphorylation in response to ER stress|regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|regulation of ER stress-induced eIF2 alpha dephosphorylation						bf	2015-02-09T11:18:14Z						biological_process											owl:Class	
GO:0046167	biolink:NamedThing	glycerol-3-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.	got7fsn_ti	glycerol-3-phosphate biosynthesis|glycerol-3-phosphate anabolism|glycerol-3-phosphate formation|glycerol-3-phosphate synthesis													biological_process											owl:Class	
GO:0010704	biolink:NamedThing	meiotic DNA double-strand break processing involved in meiotic gene conversion	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another.	got7fsn_ti														biological_process											owl:Class	
GO:1903100	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process	The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.	got7fsn_ti	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolism						bhm	2014-06-04T14:14:24Z						biological_process											owl:Class	
UBERON:0000002	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015974	biolink:NamedThing	guanosine pentaphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.	got7fsn_ti	guanosine pentaphosphate degradation|guanosine pentaphosphate breakdown|guanosine pentaphosphate catabolism|guanosine pentaphosphate (5'-pppGpp-3') catabolism|guanosine pentaphosphate (5'-pppGpp-3') catabolic process													biological_process											owl:Class	
GO:0043459	biolink:NamedThing	obsolete response to short exposure to lithium ion	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a single or short exposure to a lithium ion stimulus.	got7fsn_ti	response to short exposure to lithium ion				This term was made obsolete because 'short' is not a quantitative or meaningful measurement of time.					True				biological_process											owl:Class	
GO:1904734	biolink:NamedThing	positive regulation of electron transfer activity	Any process that activates or increases the frequency, rate or extent of electron transfer activity.	got7fsn_ti	upregulation of 2Fe-2S electron transfer carrier|up-regulation of bacterial-type ferredoxin|upregulation of mononuclear iron electron carrier|positive regulation of electron transporter activity|activation of electron transfer flavoprotein, group II|upregulation of redox-active disulfide bond electron carrier|up-regulation of electron transfer flavoprotein, group II|up regulation of electron carrier, chlorophyll electron transport system|up-regulation of thioredoxin-like 2Fe-2S ferredoxin|positive regulation of small blue copper electron carrier|up-regulation of adrenodoxin-type ferredoxin|positive regulation of bacterial-type ferredoxin|upregulation of small blue copper electron carrier|up regulation of polyferredoxin|upregulation of monocluster bacterial-type ferredoxin|up-regulation of electron transfer flavoprotein|positive regulation of redox-active disulfide bond electron carrier|positive regulation of dicluster bacterial-type ferredoxin|up regulation of monocluster bacterial-type ferredoxin|positive regulation of electron transfer flavoprotein, group I|up-regulation of rubredoxin|up-regulation of dicluster bacterial-type ferredoxin|activation of electron transfer flavoprotein, group I|up regulation of electron carrier activity|up regulation of amicyanin|upregulation of electron carrier activity|up-regulation of high-potential iron-sulfur carrier|up regulation of azurin|upregulation of chloroplast-type ferredoxin|activation of polyferredoxin|up-regulation of chloroplast-type ferredoxin|activation of small blue copper electron carrier|upregulation of electron transfer flavoprotein|upregulation of 3Fe-4S/4Fe-4S electron transfer carrier|positive regulation of rubredoxin|up-regulation of copper electron carrier|positive regulation of electron transfer flavoprotein, group II|activation of chloroplast-type ferredoxin|up regulation of 2Fe-2S electron transfer carrier|up-regulation of electron transfer flavoprotein, group I|up-regulation of polyferredoxin|up-regulation of mononuclear iron electron carrier|positive regulation of mononuclear iron electron carrier|positive regulation of polyferredoxin|up regulation of electron donor activity|upregulation of electron carrier, chlorophyll electron transport system|up-regulation of small blue copper electron carrier|up-regulation of redox-active disulfide bond electron carrier|positive regulation of electron acceptor activity|positive regulation of electron carrier, chlorophyll electron transport system|up regulation of rubredoxin|positive regulation of 3Fe-4S/4Fe-4S electron transfer carrier|upregulation of dicluster bacterial-type ferredoxin|activation of copper electron carrier|upregulation of copper electron carrier|activation of high-potential iron-sulfur carrier|activation of electron transfer flavoprotein|up regulation of electron transporter activity|positive regulation of electron donor activity|up-regulation of amicyanin|activation of dicluster bacterial-type ferredoxin|up-regulation of monocluster bacterial-type ferredoxin|activation of monocluster bacterial-type ferredoxin|up-regulation of azurin|up regulation of copper electron carrier|positive regulation of adrenodoxin-type ferredoxin|upregulation of electron acceptor activity|upregulation of high-potential iron-sulfur carrier|activation of rubredoxin|up regulation of electron transfer flavoprotein, group I|up-regulation of electron acceptor activity|activation of electron transporter activity|up regulation of iron-sulfur electron transfer carrier|up-regulation of 2Fe-2S electron transfer carrier|positive regulation of thioredoxin-like 2Fe-2S ferredoxin|activation of mononuclear iron electron carrier|positive regulation of electron transfer flavoprotein|up-regulation of electron carrier, chlorophyll electron transport system|upregulation of electron donor activity|positive regulation of azurin|up regulation of small blue copper electron carrier|positive regulation of high-potential iron-sulfur carrier|up-regulation of electron donor activity|upregulation of polyferredoxin|up regulation of 3Fe-4S/4Fe-4S electron transfer carrier|up regulation of high-potential iron-sulfur carrier|up regulation of electron transfer flavoprotein, group II|upregulation of thioredoxin-like 2Fe-2S ferredoxin|up-regulation of electron carrier activity|activation of amicyanin|up regulation of electron acceptor activity|activation of azurin|upregulation of azurin|activation of adrenodoxin-type ferredoxin|up-regulation of iron-sulfur electron transfer carrier|activation of thioredoxin-like 2Fe-2S ferredoxin|positive regulation of chloroplast-type ferredoxin|up regulation of thioredoxin-like 2Fe-2S ferredoxin|up regulation of dicluster bacterial-type ferredoxin|upregulation of electron transfer flavoprotein, group II|activation of 2Fe-2S electron transfer carrier|upregulation of bacterial-type ferredoxin|positive regulation of amicyanin|up-regulation of electron transporter activity|up regulation of bacterial-type ferredoxin|upregulation of iron-sulfur electron transfer carrier|up regulation of chloroplast-type ferredoxin|positive regulation of monocluster bacterial-type ferredoxin|up-regulation of 3Fe-4S/4Fe-4S electron transfer carrier|activation of electron carrier activity|upregulation of electron transporter activity|upregulation of electron transfer flavoprotein, group I|up regulation of electron transfer flavoprotein|up regulation of adrenodoxin-type ferredoxin|activation of 3Fe-4S/4Fe-4S electron transfer carrier|upregulation of amicyanin|positive regulation of 2Fe-2S electron transfer carrier|activation of redox-active disulfide bond electron carrier|activation of iron-sulfur electron transfer carrier|activation of electron carrier, chlorophyll electron transport system|up regulation of redox-active disulfide bond electron carrier|positive regulation of iron-sulfur electron transfer carrier|upregulation of adrenodoxin-type ferredoxin|activation of electron acceptor activity|activation of electron donor activity|positive regulation of copper electron carrier|upregulation of rubredoxin|activation of bacterial-type ferredoxin|up regulation of mononuclear iron electron carrier						lb	2015-10-15T07:51:32Z						biological_process											owl:Class	
GO:0016025	biolink:NamedThing	obsolete proteasome endopeptidase regulator	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	proteasome endopeptidase regulator				This term was made obsolete because it does not represent a molecular function.	GO:0004175				True				molecular_function											owl:Class	
GO:1903015	biolink:NamedThing	regulation of exo-alpha-sialidase activity	Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity.	got7fsn_ti	regulation of acetylneuraminyl hydrolase activity|regulation of sialidase activity|regulation of acetylneuraminidase activity|regulation of neuraminidase activity|regulation of N-acylneuraminate glycohydrolase activity|regulation of alpha-neuraminidase activity				human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA)		rl	2014-05-14T18:15:11Z						biological_process											owl:Class	
GO:1900538	biolink:NamedThing	obsolete positive regulation of glucose homeostasis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose homeostasis.	got7fsn_ti	upregulation of glucose homeostasis|up-regulation of glucose homeostasis|activation of glucose homeostasis|up regulation of glucose homeostasis|positive regulation of glucose homeostasis				This term was obsoleted at the TermGenie Gatekeeper stage.		hjd	2012-05-10T06:53:38Z		True				biological_process											owl:Class	
GO:0071989	biolink:NamedThing	establishment of protein localization to spindle pole body	The directed movement of a protein to a specific location at the spindle pole body.	got7fsn_ti	establishment of protein localisation to spindle pole body						mah	2010-10-25T11:01:17Z						biological_process											owl:Class	
GO:0070347	biolink:NamedThing	regulation of brown fat cell proliferation	Any process that modulates the frequency, rate or extent of brown fat cell proliferation.	got7fsn_ti	regulation of brown adipose cell proliferation|regulation of brown adipocyte proliferation													biological_process											owl:Class	
GO:0005013	biolink:NamedThing	obsolete neurotrophin TRK receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	neurotrophin TRK receptor activity				This term was made obsolete because it represents a gene product.	GO:0019838|GO:0043121|GO:0007165|GO:0004714				True				molecular_function											owl:Class	
GO:0019306	biolink:NamedThing	GDP-D-rhamnose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-D-rhamnose synthesis|GDP-D-rhamnose formation|GDP-D-rhamnose biosynthesis|GDP-D-rhamnose anabolism											MetaCyc:GDPRHAMSYN-PWY		biological_process											owl:Class	
GO:1903333	biolink:NamedThing	negative regulation of protein folding	Any process that stops, prevents or reduces the frequency, rate or extent of protein folding.	got7fsn_ti	down regulation of co-chaperonin activity|inhibition of protein complex assembly, multichaperone pathway|down regulation of alpha-tubulin folding|inhibition of beta-tubulin folding|downregulation of chaperone activity|negative regulation of beta-tubulin folding|down regulation of beta-tubulin folding|down-regulation of alpha-tubulin folding|inhibition of chaperone activity|down-regulation of chaperone activity|down-regulation of co-chaperonin activity|negative regulation of chaperonin-mediated tubulin folding|down-regulation of chaperonin ATPase activity|negative regulation of chaperonin ATPase activity|negative regulation of alpha-tubulin folding|negative regulation of non-chaperonin molecular chaperone ATPase activity|negative regulation of protein complex assembly, multichaperone pathway|inhibition of chaperonin ATPase activity|inhibition of alpha-tubulin folding|down regulation of chaperone activity|down-regulation of co-chaperone activity|inhibition of co-chaperone activity|downregulation of protein complex assembly, multichaperone pathway|down-regulation of protein folding|downregulation of co-chaperone activity|down-regulation of glycoprotein-specific chaperone activity|down-regulation of beta-tubulin folding|downregulation of protein folding|inhibition of co-chaperonin activity|down regulation of co-chaperone activity|inhibition of chaperonin-mediated tubulin folding|inhibition of protein folding|downregulation of chaperonin-mediated tubulin folding|downregulation of chaperonin ATPase activity|down regulation of chaperonin-mediated tubulin folding|down-regulation of chaperonin-mediated tubulin folding|negative regulation of glycoprotein-specific chaperone activity|down regulation of protein folding|downregulation of beta-tubulin folding|down regulation of protein complex assembly, multichaperone pathway|downregulation of alpha-tubulin folding|inhibition of glycoprotein-specific chaperone activity|negative regulation of co-chaperonin activity|down regulation of non-chaperonin molecular chaperone ATPase activity|down-regulation of non-chaperonin molecular chaperone ATPase activity|negative regulation of co-chaperone activity|downregulation of non-chaperonin molecular chaperone ATPase activity|negative regulation of chaperone activity|down-regulation of protein complex assembly, multichaperone pathway|downregulation of glycoprotein-specific chaperone activity|downregulation of co-chaperonin activity|down regulation of glycoprotein-specific chaperone activity|down regulation of chaperonin ATPase activity|inhibition of non-chaperonin molecular chaperone ATPase activity						vw	2014-08-18T13:14:42Z						biological_process											owl:Class	
GO:0042354	biolink:NamedThing	L-fucose metabolic process	The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.	got7fsn_ti	L-fucose metabolism													biological_process											owl:Class	
GO:0042194	biolink:NamedThing	quinate biosynthetic process	The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid.	got7fsn_ti	quinic acid biosynthesis|quinic acid biosynthetic process|quinate synthesis|quinate anabolism|quinate formation|quinate biosynthesis													biological_process											owl:Class	
GO:0061189	biolink:NamedThing	positive regulation of sclerotome development	Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.	got7fsn_ti							dph	2010-07-14T09:17:23Z						biological_process											owl:Class	
GO:1903819	biolink:NamedThing	obsolete detection of stimulus involved in mitotic cytokinesis checkpoint	OBSOLETE. Any detection of stimulus that is involved in a mitotic cytokinesis checkpoint.	got7fsn_ti	stimulus sensing involved in mitotic cytokinesis checkpoint|stimulus detection involved in mitotic cytokinesis checkpoint|perception of stimulus involved in mitotic cytokinesis checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		jl	2015-01-19T15:03:16Z		True				biological_process											owl:Class	
GO:1903033	biolink:NamedThing	positive regulation of microtubule plus-end binding	Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding.	got7fsn_ti	upregulation of microtubule plus-end binding|up regulation of microtubule plus-end binding|up-regulation of microtubule plus-end binding|activation of microtubule plus-end binding						hjd	2014-05-16T18:38:38Z						biological_process											owl:Class	
GO:1903695	biolink:NamedThing	obsolete MAPK cascade involved in ascospore formation	OBSOLETE. Any MAPK cascade that is involved in ascospore formation.	got7fsn_ti	mitogen-activated protein kinase cascade involved in ascospore biosynthesis|MAPK cascade involved in ascospore biosynthesis|MAP kinase cascade involved in ascospore biosynthesis|MAPK signaling involved in ascospore formation|MAPK signalling involved in ascospore formation|MAPKKK cascade involved in ascospore formation|MAPK signal transduction involved in ascospore biosynthesis|MAPK signalling involved in ascospore biosynthesis|MAPK signal transduction involved in ascospore formation|MAPK signaling involved in ascospore biosynthesis|MAPKKK cascade during sporulation involved in ascospore formation|MAP kinase cascade involved in ascospore formation|MAPKKK cascade involved in ascospore biosynthesis|ERK/MAPK cascade involved in ascospore biosynthesis|ERK/MAPK cascade involved in ascospore formation|MAP kinase kinase kinase cascade involved in ascospore formation|mitogen-activated protein kinase cascade involved in ascospore formation|MAPKKK cascade during sporulation involved in ascospore biosynthesis|MAP kinase kinase kinase cascade involved in ascospore biosynthesis	https://github.com/geneontology/go-ontology/issues/14323			This term was obsoleted because it represents a GO-CAM model.		al	2014-12-02T22:09:18Z		True				biological_process											owl:Class	
GO:1902070	biolink:NamedThing	positive regulation of sphingolipid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of sphingolipid signaling.	got7fsn_ti	activation of sphingolipid mediated signaling pathway|upregulation of sphingolipid signaling pathway|up regulation of sphingolipid signaling pathway|upregulation of sphingolipid mediated signaling pathway|up-regulation of sphingolipid mediated signaling pathway|up-regulation of sphingolipid signaling pathway|activation of sphingolipid signaling pathway|positive regulation of sphingolipid signaling pathway|up regulation of sphingolipid mediated signaling pathway						bf	2013-04-18T13:24:56Z						biological_process											owl:Class	
GO:1905167	biolink:NamedThing	positive regulation of lysosomal protein catabolic process	Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process.	got7fsn_ti	positive regulation of cellular protein degradation in lysosome|upregulation of lysosomal protein catabolism|upregulation of cellular protein catabolic process in lysosome|positive regulation of cellular protein breakdown in lysosome|up regulation of cellular protein catabolism in lysosome|up regulation of proteolysis within lysosome|activation of cellular protein degradation in lysosome|up regulation of cellular protein catabolic process in lysosome|positive regulation of lysosomal protein degradation|up regulation of lysosomal proteolysis|activation of cellular protein catabolism in lysosome|up regulation of lysosomal protein catabolic process|activation of lysosomal proteolysis|activation of lysosomal protein catabolism|up regulation of cellular protein degradation in lysosome|up-regulation of lysosomal proteolysis|up regulation of cellular protein breakdown in lysosome|upregulation of cellular protein catabolism in lysosome|upregulation of cellular protein breakdown in lysosome|positive regulation of cellular protein catabolism in lysosome|upregulation of lysosomal protein catabolic process|positive regulation of cellular protein catabolic process in lysosome|up-regulation of cellular protein catabolic process in lysosome|activation of lysosomal protein catabolic process|positive regulation of lysosomal proteolysis|upregulation of lysosomal proteolysis|up-regulation of lysosomal protein catabolism|up-regulation of cellular protein breakdown in lysosome|up regulation of lysosomal protein catabolism|upregulation of proteolysis within lysosome|up-regulation of cellular protein catabolism in lysosome|up regulation of lysosomal protein degradation|activation of proteolysis within lysosome|activation of cellular protein catabolic process in lysosome|positive regulation of proteolysis within lysosome|activation of lysosomal protein degradation|up-regulation of proteolysis within lysosome|up-regulation of lysosomal protein degradation|up-regulation of cellular protein degradation in lysosome|positive regulation of lysosomal protein catabolism|upregulation of cellular protein degradation in lysosome|activation of cellular protein breakdown in lysosome|upregulation of lysosomal protein degradation|up-regulation of lysosomal protein catabolic process						bf	2016-04-26T12:10:19Z						biological_process											owl:Class	
GO:1904619	biolink:NamedThing	response to dimethyl sulfoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.	got7fsn_ti	response to DMSO						sl	2015-08-27T19:13:49Z						biological_process											owl:Class	
GO:1904946	biolink:NamedThing	obsolete cellular response to cobalt(II) acetate	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2016-02-02T16:48:00Z		True				biological_process											owl:Class	
GO:1901963	biolink:NamedThing	regulation of cell proliferation involved in outflow tract morphogenesis	Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.	got7fsn_ti							dph	2013-02-20T20:30:26Z						biological_process											owl:Class	
GO:1900524	biolink:NamedThing	obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of flocculation via cell wall protein-carbohydrate interaction process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	up-regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|up regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|activation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|upregulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM.		dgf	2012-05-03T05:13:41Z		True				biological_process											owl:Class	
GO:0051399	biolink:NamedThing	obsolete N-terminal arginine aminopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of an arginine residue from the N-terminal of an oligopeptide or polypeptide chain.	got7fsn_ti	arginine aminopeptidase activity|N-terminal arginine aminopeptidase activity|argininyl aminopeptidase activity			GO:0004177	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0043569	biolink:NamedThing	negative regulation of insulin-like growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling.	got7fsn_ti	negative regulation of insulin-like growth factor receptor signalling pathway|negative regulation of IGF receptor signalling pathway|inhibition of insulin-like growth factor receptor signaling pathway|negative regulation of IGF receptor signaling pathway|downregulation of insulin-like growth factor receptor signaling pathway|down regulation of insulin-like growth factor receptor signaling pathway|down-regulation of insulin-like growth factor receptor signaling pathway													biological_process											owl:Class	
GO:1900331	biolink:NamedThing	negative regulation of methane biosynthetic process from trimethylamine	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine.	got7fsn_ti	down regulation of methane biosynthetic process from trimethylamine|downregulation of methane biosynthetic process from trimethylamine|inhibition of methane biosynthetic process from trimethylamine|down-regulation of methane biosynthetic process from trimethylamine						tt	2012-04-06T01:53:12Z						biological_process											owl:Class	
GO:1904079	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process	OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in negative regulation of neuron apoptotic process.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of programmed cell death, neurons|negative regulation of global transcription from Pol II promoter involved in neuron survival|downregulation of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from Pol II promoter involved in downregulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down regulation of transcription from RNA polymerase II promoter involved in neuron survival|inhibition of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter, global involved in down-regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in neuron survival|downregulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptotic process|negative regulation of transcription from Pol II promoter involved in down regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter, global involved in downregulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in down-regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in inhibition of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from RNA polymerase II promoter involved in neuron survival|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptotic process|inhibition of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in neuron survival|downregulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down-regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in inhibition of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptotic process|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in downregulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in down-regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from Pol II promoter involved in neuron survival|negative regulation of global transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons|down-regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in inhibition of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in neuron survival|down regulation of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter, global involved in down regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in down regulation of neuron apoptosis				This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0043524|GO:0000122	kmv	2015-03-24T17:28:41Z		True				biological_process											owl:Class	
GO:0072036	biolink:NamedThing	mesenchymal to epithelial transition involved in renal vesicle formation	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.	got7fsn_ti							mah	2010-01-25T03:04:24Z						biological_process											owl:Class	
GO:0090147	biolink:NamedThing	obsolete regulation of establishment of mitochondrion localization involved in mitochondrial fission	OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.	got7fsn_ti	regulation of mitochondrial localization involved in mitochondrial fission|regulation of establishment of mitochondrion localisation involved in mitochondrial fission	https://github.com/geneontology/go-ontology/issues/18417			This term was obsoleted because it represented a phenotype.	GO:0000266|GO:0000002	tb	2009-12-08T03:01:01Z		True				biological_process											owl:Class	
GO:1901606	biolink:NamedThing	alpha-amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid.	got7fsn_ti	alpha-amino acid catabolism|alpha-amino acid degradation|alpha-amino acid breakdown						tb	2012-11-08T17:39:54Z						biological_process											owl:Class	
GO:0033264	biolink:NamedThing	obsolete bontoxilysin activity	OBSOLETE. Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.	got7fsn_ti	botulinum neurotoxin activity|BoNT|bontoxilysin activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0003370	biolink:NamedThing	cell-cell adhesion involved in mesendodermal cell migration	The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm.	got7fsn_ti							dph	2009-12-08T05:33:51Z						biological_process											owl:Class	
GO:1904483	biolink:NamedThing	synthetic cannabinoid binding	Binding to synthetic cannabinoid.	got7fsn_ti							mr	2015-07-14T22:30:09Z						molecular_function											owl:Class	
GO:1901718	biolink:NamedThing	obsolete regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of dipeptide transmembrane transport.	got7fsn_ti					The term was obsoleted because it is better represented by a GO-CAM model.		pr	2012-12-19T17:04:04Z		True				biological_process											owl:Class	
GO:0140323	biolink:NamedThing	solute:anion antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(in) + solute(out) = anion(out) + solute(in).	got7fsn_ti							pg	2019-04-03T16:23:14Z						molecular_function											owl:Class	
GO:1903770	biolink:NamedThing	negative regulation of beta-galactosidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity.	got7fsn_ti	downregulation of beta-lactosidase activity|down-regulation of beta-galactosidase activity|inhibition of beta-galactosidase activity|down-regulation of lactose hydrolysis|downregulation of beta-galactosidase activity|down regulation of exo-(1->4)-beta-D-galactanase activity|negative regulation of beta-D-lactosidase activity|inhibition of maxilact|downregulation of exo-(1->4)-beta-D-galactanase activity|inhibition of lactozym|down regulation of maxilact|downregulation of beta-D-galactanase activity|down-regulation of exo-(1->4)-beta-D-galactanase activity|down regulation of oryzatym|inhibition of beta-D-galactoside galactohydrolase activity|inhibition of beta-D-lactosidase activity|downregulation of S 2107|negative regulation of sumiklat|downregulation of lactose hydrolysis|down-regulation of maxilact|down-regulation of oryzatym|downregulation of beta-D-lactosidase activity|negative regulation of trilactase activity|down regulation of beta-D-lactosidase activity|down-regulation of beta-D-lactosidase activity|negative regulation of lactozym|negative regulation of hydrolact|down regulation of S 2107|down-regulation of S 2107|downregulation of hydrolact|down regulation of hydrolact|down regulation of sumiklat|inhibition of sumiklat|negative regulation of S 2107|down regulation of lactose hydrolysis|inhibition of oryzatym|down-regulation of sumiklat|negative regulation of beta-lactosidase activity|downregulation of lactozym|inhibition of trilactase activity|downregulation of trilactase activity|down-regulation of beta-D-galactoside galactohydrolase activity|inhibition of hydrolact|negative regulation of beta-D-galactoside galactohydrolase activity|negative regulation of lactose hydrolysis|inhibition of exo-(1->4)-beta-D-galactanase activity|negative regulation of maxilact|down-regulation of lactozym|negative regulation of exo-(1->4)-beta-D-galactanase activity|down-regulation of beta-D-galactanase activity|down regulation of beta-lactosidase activity|down regulation of lactozym|downregulation of oryzatym|negative regulation of oryzatym|downregulation of sumiklat|downregulation of beta-D-galactoside galactohydrolase activity|down-regulation of beta-lactosidase activity|down regulation of trilactase activity|down-regulation of hydrolact|down regulation of beta-galactosidase activity|inhibition of lactose hydrolysis|down regulation of beta-D-galactoside galactohydrolase activity|inhibition of S 2107|negative regulation of beta-D-galactanase activity|downregulation of maxilact|inhibition of beta-lactosidase activity|down-regulation of trilactase activity|inhibition of beta-D-galactanase activity|down regulation of beta-D-galactanase activity						nc	2015-01-06T10:53:22Z						biological_process											owl:Class	
GO:1905481	biolink:NamedThing	obsolete cytoplasmic sequestering of protein involved in mitotic DNA replication checkpoint	OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic DNA replication checkpoint.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		vw	2016-09-22T18:20:35Z		True				biological_process											owl:Class	
GO:0002232	biolink:NamedThing	leukocyte chemotaxis involved in inflammatory response	The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.	got7fsn_ti	leucocyte chemotaxis during inflammatory response|leukocyte chemotaxis during inflammatory response|immune cell chemotaxis during inflammatory response													biological_process											owl:Class	
GO:0002885	biolink:NamedThing	positive regulation of hypersensitivity	Any process that activates or increases the frequency, rate, or extent of hypersensitivity.	got7fsn_ti	up-regulation of hypersensitivity|activation of hypersensitivity|upregulation of hypersensitivity|stimulation of hypersensitivity|up regulation of hypersensitivity													biological_process											owl:Class	
GO:0006672	biolink:NamedThing	ceramide metabolic process	The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.	got7fsn_ti	ceramide metabolism													biological_process											owl:Class	
GO:1902380	biolink:NamedThing	positive regulation of endoribonuclease activity	Any process that activates or increases the frequency, rate or extent of endoribonuclease activity.	got7fsn_ti	up-regulation of endoribonuclease activity|up-regulation of endonuclease G activity|upregulation of endonuclease G activity|upregulation of endoribonuclease activity|positive regulation of endonuclease G activity|up regulation of endoribonuclease activity|activation of endoribonuclease activity|up regulation of endonuclease G activity|activation of endonuclease G activity						bf	2013-09-02T14:14:29Z						biological_process											owl:Class	
GO:1904800	biolink:NamedThing	negative regulation of neuron remodeling	Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling.	got7fsn_ti	inhibition of axon pruning|downregulation of axon pruning|negative regulation of axon pruning|downregulation of neuronal remodeling|inhibition of neuron remodeling|down regulation of neuronal remodeling|down-regulation of neuron remodeling|down-regulation of axon pruning|inhibition of neuronal remodeling|negative regulation of neuronal remodeling|down regulation of axon pruning|down-regulation of neuronal remodeling|downregulation of neuron remodeling|down regulation of neuron remodeling				cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype)		es	2015-11-09T13:47:00Z						biological_process											owl:Class	
GO:0002547	biolink:NamedThing	positive regulation of tissue kallikrein-kinin cascade	Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade.	got7fsn_ti	up-regulation of tissue kallikrein-kinin cascade|upregulation of tissue kallikrein-kinin cascade|stimulation of tissue kallikrein-kinin cascade|activation of tissue kallikrein-kinin cascade|positive regulation of glandular kallikrein-kinin cascade|up regulation of tissue kallikrein-kinin cascade													biological_process											owl:Class	
GO:0008848	biolink:NamedThing	obsolete enterobactin synthetase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	enterochelin synthetase activity|nonribosomal peptide synthetase|enterobactin synthetase			GO:0009239	This term was made obsolete because it represents a process rather than a function.					True	GO:0008850			molecular_function											owl:Class	
GO:0090379	biolink:NamedThing	secondary cell wall biogenesis involved in seed trichome differentiation	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.	got7fsn_ti	seed trichome secondary wall biosynthesis|secondary cell wall biosynthesis involved in seed trichome differentiation				The processes involved in the massive amount of secondary wall cellulose synthesis in seed trichomes continue to 30 DPA in Gossypium spp.		tb	2010-09-15T02:24:34Z						biological_process											owl:Class	
GO:0071302	biolink:NamedThing	cellular response to vitamin B2	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.	got7fsn_ti	cellular response to riboflavin						mah	2009-12-10T04:34:52Z						biological_process											owl:Class	
GO:1904960	biolink:NamedThing	positive regulation of cytochrome-c oxidase activity	Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.	got7fsn_ti	activation of ferrocytochrome-c:oxygen oxidoreductase|positive regulation of cytochrome aa3 activity|up regulation of ferrocytochrome c oxidase|upregulation of cytochrome c oxidase activity|activation of cbb3-type cytochrome c oxidase|up regulation of warburg's respiratory enzyme activity|up regulation of complex IV (mitochondrial electron transport) activity|up-regulation of indophenol oxidase|activation of ferrocytochrome c oxidase|activation of NADH cytochrome c oxidase|upregulation of ba3-type cytochrome c oxidase|activation of indophenol oxidase|upregulation of warburg's respiratory enzyme activity|upregulation of cytochrome a3 activity|activation of caa3-type cytochrome c oxidase|activation of cytochrome aa3 activity|up-regulation of cytochrome a3 activity|up-regulation of ferrocytochrome-c:oxygen oxidoreductase|upregulation of cbb3-type cytochrome c oxidase|up regulation of NADH cytochrome c oxidase|upregulation of cytochrome-c oxidase activity|up regulation of ferrocytochrome-c:oxygen oxidoreductase|up regulation of aa3-type cytochrome c oxidase|up-regulation of cytochrome c oxidase activity|up regulation of indophenol oxidase|up regulation of caa3-type cytochrome c oxidase|positive regulation of cytochrome c oxidase activity|positive regulation of warburg's respiratory enzyme activity|positive regulation of cytochrome a3 activity|activation of indophenolase|up-regulation of warburg's respiratory enzyme activity|activation of cytochrome-c oxidase activity|upregulation of cytochrome aa3 activity|positive regulation of ferrocytochrome c oxidase|up regulation of indophenolase|up-regulation of caa3-type cytochrome c oxidase|activation of cytochrome a3 activity|up-regulation of aa3-type cytochrome c oxidase|positive regulation of cytochrome oxidase activity|positive regulation of NADH cytochrome c oxidase|upregulation of caa3-type cytochrome c oxidase|up regulation of cytochrome a3 activity|upregulation of aa3-type cytochrome c oxidase|up-regulation of indophenolase|up-regulation of ba3-type cytochrome c oxidase|positive regulation of ba3-type cytochrome c oxidase|upregulation of ferrocytochrome-c:oxygen oxidoreductase|positive regulation of complex IV (mitochondrial electron transport) activity|up-regulation of cbb3-type cytochrome c oxidase|upregulation of ferrocytochrome c oxidase|upregulation of NADH cytochrome c oxidase|up-regulation of NADH cytochrome c oxidase|up regulation of cytochrome oxidase activity|activation of cytochrome c oxidase activity|upregulation of indophenolase|positive regulation of cbb3-type cytochrome c oxidase|up-regulation of complex IV (mitochondrial electron transport) activity|up regulation of cytochrome-c oxidase activity|positive regulation of aa3-type cytochrome c oxidase|up regulation of ba3-type cytochrome c oxidase|activation of aa3-type cytochrome c oxidase|up regulation of cytochrome c oxidase activity|up-regulation of cytochrome oxidase activity|activation of warburg's respiratory enzyme activity|upregulation of cytochrome oxidase activity|up-regulation of cytochrome aa3 activity|up-regulation of cytochrome-c oxidase activity|up regulation of cbb3-type cytochrome c oxidase|positive regulation of caa3-type cytochrome c oxidase|up regulation of cytochrome aa3 activity|activation of ba3-type cytochrome c oxidase|positive regulation of indophenol oxidase|up-regulation of ferrocytochrome c oxidase|positive regulation of ferrocytochrome-c:oxygen oxidoreductase|activation of complex IV (mitochondrial electron transport) activity|upregulation of indophenol oxidase|positive regulation of indophenolase|activation of cytochrome oxidase activity|upregulation of complex IV (mitochondrial electron transport) activity						tb	2016-02-09T22:18:43Z						biological_process											owl:Class	
GO:0010037	biolink:NamedThing	response to carbon dioxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0051136	biolink:NamedThing	regulation of NK T cell differentiation	Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.	got7fsn_ti	regulation of NK T lymphocyte differentiation|regulation of NKT cell differentiation|regulation of natural killer T cell differentiation|regulation of NK T-cell differentiation|regulation of NK T-lymphocyte differentiation|regulation of natural T cell differentiation|regulation of NT cell differentiation|regulation of NK T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1905828	biolink:NamedThing	regulation of prostaglandin catabolic process	Any process that modulates the frequency, rate or extent of prostaglandin catabolic process.	got7fsn_ti	regulation of prostaglandin breakdown|regulation of prostaglandin catabolism|regulation of prostaglandin degradation						sl	2017-01-16T21:36:39Z						biological_process											owl:Class	
GO:0034437	biolink:NamedThing	obsolete glycoprotein transmembrane transporter activity	OBSOLETE. Enables the transfer of a glycoprotein from one side of a membrane to the other.	got7fsn_ti	glycoprotein transporter activity	https://github.com/geneontology/go-ontology/issues/17130			This term was obsoleted because there is no transmembrane transporter specific for glycoproteins.					True				molecular_function											owl:Class	
GO:2000216	biolink:NamedThing	positive regulation of proline metabolic process	Any process that activates or increases the frequency, rate or extent of proline metabolic process.	got7fsn_ti	positive regulation of proline metabolism						mah	2010-11-03T02:45:27Z						biological_process											owl:Class	
GO:0039546	biolink:NamedThing	obsolete suppression by virus of host MAVS activity by MAVS proteolysis	OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host MAVS (mitochondrial inhibitor of viral signaling) protein by cleavage of peptide bonds, thereby inhibiting the host innate immune response. For example, MAVS harbors a C-terminal transmembrane domain that targets it to the mitochondrial outer membrane; cleavage within this domain removes MAVS from the membrane, thus preventing it from signaling.	got7fsn_ti	viral protease cleavage of MAVS				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-19T02:49:44Z		True				biological_process											owl:Class	
GO:0007347	biolink:NamedThing	regulation of preblastoderm mitotic cell cycle	A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle.	got7fsn_ti	preblastoderm mitotic cell cycle modulation|regulation of progression through preblastoderm mitotic cell cycle|regulation of preblastoderm mitotic cell cycle progression|preblastoderm mitotic cell cycle regulation|preblastoderm mitotic cell cycle regulator|modulation of preblastoderm mitotic cell cycle progression													biological_process											owl:Class	
GO:1902527	biolink:NamedThing	positive regulation of protein monoubiquitination	Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.	got7fsn_ti	up-regulation of protein monoubiquitination|upregulation of protein monoubiquitylation|upregulation of protein monoubiquitinylation|up regulation of protein monoubiquitination|activation of protein monoubiquitination|upregulation of protein monoubiquitination|up-regulation of protein monoubiquitinylation|up-regulation of protein monoubiquitylation|activation of protein monoubiquitylation|activation of protein monoubiquitinylation|up regulation of protein monoubiquitylation|positive regulation of protein monoubiquitylation|positive regulation of protein monoubiquitinylation|up regulation of protein monoubiquitinylation				An example is BIRC2 (UniProt ID Q13490) in PMID:21931591.		ppm	2013-12-02T09:59:21Z						biological_process											owl:Class	
GO:0050661	biolink:NamedThing	NADP binding	Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.	got7fsn_ti	NADP+ or NADPH binding|nicotinamide adenine dinucleotide phosphate binding|NADP or NADPH binding													molecular_function											owl:Class	
GO:1903540	biolink:NamedThing	establishment of protein localization to postsynaptic membrane	The directed movement of a protein to a specific location in a postsynaptic membrane.	got7fsn_ti	establishment of protein localisation in postsynaptic membrane|establishment of protein localization in postsynaptic membrane|establishment of protein localisation to postsynaptic membrane						kmv	2014-10-10T11:24:03Z						biological_process											owl:Class	
GO:1902327	biolink:NamedThing	bacterial-type DNA replication DNA ligation	Any DNA ligation that is involved in bacterial-type DNA replication.	got7fsn_ti	DNA ligation involved in bacterial-type DNA replication						jl	2013-07-25T10:47:46Z						biological_process											owl:Class	
GO:1902772	biolink:NamedThing	positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway	Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway.	got7fsn_ti	up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signaling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signalling pathway|up regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signalling pathway|stimulation of two-component signal transduction involved in H2O2 mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signalling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in H2O2 mediated signaling pathway|up regulation of two-component signal transduction involved in H2O2 mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|activation of two-component signal transduction involved in H2O2 mediated signaling pathway|activation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|upregulation of two-component signal transduction involved in H2O2 mediated signaling pathway|up regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|activation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|upregulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|up-regulation of two-component signal transduction involved in H2O2 mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signaling pathway|up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|positive regulation of phosphorelay signal transduction system involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|upregulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway						al	2014-03-17T11:42:08Z						biological_process											owl:Class	
GO:1903006	biolink:NamedThing	positive regulation of protein K63-linked deubiquitination	Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination.	got7fsn_ti	activation of protein K63-linked deubiquitination|up-regulation of protein K63-linked deubiquitination|upregulation of protein K63-linked deubiquitination|up regulation of protein K63-linked deubiquitination						bf	2014-05-12T15:40:55Z						biological_process											owl:Class	
GO:1904484	biolink:NamedThing	cloacal gland development	The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure.	got7fsn_ti							mr	2015-07-15T22:14:39Z						biological_process											owl:Class	
GO:0002577	biolink:NamedThing	regulation of antigen processing and presentation	Any process that modulates the frequency, rate, or extent of antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:1903412	biolink:NamedThing	response to bile acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.	got7fsn_ti							rl	2014-09-03T12:45:43Z						biological_process											owl:Class	
GO:0090620	biolink:NamedThing	obsolete APC-Cdc20 complex	OBSOLETE. An anaphase promoting complex bound to the fizzy family APC activator Cdc20/Slp1 which regulates the metaphase anaphase transition by activating the APC/C to target the anaphase inhibitor securin and promotes sister chromatid separation.	got7fsn_ti	APC-Slp1 complex|APC-fizzy complex|mitotic anaphase promotic complex				This term was made obsolete because it is too fine-grained for GO. Consider Complex Portal EBI-1252490, Anaphase-Promoting Complex variant 2 as an alternate term.	GO:0005680	tb	2014-12-17T17:01:38Z		True				cellular_component											owl:Class	
GO:1904075	biolink:NamedThing	positive regulation of trophectodermal cell proliferation	Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation.	got7fsn_ti	up-regulation of trophectoderm cell proliferation|positive regulation of trophectoderm cell proliferation|up-regulation of trophectodermal cell proliferation|up regulation of trophectodermal cell proliferation|upregulation of trophectoderm cell proliferation|activation of trophectoderm cell proliferation|upregulation of trophectodermal cell proliferation|activation of trophectodermal cell proliferation|up regulation of trophectoderm cell proliferation						tb	2015-03-20T16:56:08Z						biological_process											owl:Class	
GO:0042199	biolink:NamedThing	cyanuric acid metabolic process	The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives.	got7fsn_ti	cyanuric acid metabolism													biological_process											owl:Class	
CHEBI:57871	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006663	biolink:NamedThing	platelet activating factor biosynthetic process	The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.	got7fsn_ti	platelet activating factor anabolism|platelet activating factor biosynthesis|platelet activating factor synthesis|PAF biosynthesis|PAF biosynthetic process|platelet activating factor formation													biological_process											owl:Class	
GO:2000801	biolink:NamedThing	negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.	got7fsn_ti	negative regulation of endocardial cushion to mesenchymal transition involved in valve formation						bf	2011-07-01T12:31:22Z						biological_process											owl:Class	
GO:0032697	biolink:NamedThing	negative regulation of interleukin-14 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production.	got7fsn_ti	down-regulation of interleukin-14 production|negative regulation of IL-14 production|down regulation of interleukin-14 production|downregulation of interleukin-14 production|inhibition of interleukin-14 production|negative regulation of interleukin-14 biosynthetic process										GO:0045370			biological_process											owl:Class	
GO:2000820	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.	got7fsn_ti	downregulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|inhibition of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from Pol II promoter involved in nonstriated muscle cell differentiation|negative regulation of global transcription from Pol II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter, global involved in nonstriated muscle cell differentiation|down-regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|downregulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of global transcription from Pol II promoter involved in smooth muscle cell differentiation|downregulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|inhibition of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down-regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from Pol II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter, global involved in smooth muscle cell differentiation|down-regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|downregulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down-regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation						bf	2011-07-14T08:25:05Z						biological_process											owl:Class	
GO:0006140	biolink:NamedThing	regulation of nucleotide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.	got7fsn_ti	regulation of nucleotide metabolism													biological_process											owl:Class	
GO:0004281	biolink:NamedThing	obsolete pancreatic elastase II activity	OBSOLETE. Catalysis of the preferential cleavage of Leu-Xaa, Met-Xaa and Phe-Xaa. Hydrolyzes elastin.	got7fsn_ti	pancreatic elastase II activity|pancreatic elastase 2			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0090061	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001281	biolink:NamedThing	regulation of muscle cell chemotaxis toward tendon cell	Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell.	got7fsn_ti	regulation of muscle cell attraction|regulation of muscle cell chemotaxis towards tendon cell						bf	2011-12-15T10:39:36Z						biological_process											owl:Class	
GO:1900305	biolink:NamedThing	positive regulation of laminaritriose transport	Any process that activates or increases the frequency, rate or extent of laminaritriose transport.	got7fsn_ti	up-regulation of laminaritriose transport|upregulation of laminaritriose transport|up regulation of laminaritriose transport|activation of laminaritriose transport						tt	2012-04-05T07:58:06Z						biological_process											owl:Class	
GO:1902015	biolink:NamedThing	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process	The chemical reactions and pathways involving poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.	got7fsn_ti	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism						tb	2013-03-22T15:43:55Z						biological_process											owl:Class	
GO:1902006	biolink:NamedThing	negative regulation of proline biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process.	got7fsn_ti	downregulation of proline formation|negative regulation of proline anabolism|down regulation of proline anabolism|inhibition of proline synthesis|down regulation of proline formation|negative regulation of proline formation|downregulation of proline biosynthesis|negative regulation of proline synthesis|down-regulation of proline synthesis|negative regulation of proline biosynthesis|down regulation of proline synthesis|down-regulation of proline biosynthesis|inhibition of proline formation|downregulation of proline biosynthetic process|down-regulation of proline biosynthetic process|inhibition of proline biosynthetic process|inhibition of proline biosynthesis|down-regulation of proline anabolism|down regulation of proline biosynthetic process|down regulation of proline biosynthesis|down-regulation of proline formation|downregulation of proline synthesis|downregulation of proline anabolism|inhibition of proline anabolism						tb	2013-03-21T21:48:12Z						biological_process											owl:Class	
GO:2001114	biolink:NamedThing	positive regulation of cellular response to hepatocyte growth factor stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.	got7fsn_ti	positive regulation of cellular response to HGF stimulus						dph	2011-10-05T05:43:26Z						biological_process											owl:Class	
GO:0016676	biolink:NamedThing	obsolete oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen.	got7fsn_ti	oxidoreductase activity, acting on haem group of donors, oxygen as acceptor	https://github.com/geneontology/go-ontology/issues/20923			This term was obsoleted because Enzyme Commission (EC) has rehoused all its descendant classes,  and this is now a grouping term with not children.					True		EC:1.9.3.-		molecular_function											owl:Class	
GO:0090020	biolink:NamedThing	obsolete regulation of transcription involved in posterior neural plate formation	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the posterior neural plate.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0090018	tb	2009-07-29T11:39:29Z		True				biological_process											owl:Class	
GO:1905232	biolink:NamedThing	cellular response to L-glutamate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.	got7fsn_ti	cellular response to L-glutamate(1-)						sl	2016-06-07T17:30:08Z						biological_process											owl:Class	
GO:0031650	biolink:NamedThing	regulation of heat generation	Any process that modulates the rate or extent of heat generation.	got7fsn_ti														biological_process											owl:Class	
GO:0046772	biolink:NamedThing	viral budding from outer nuclear membrane	The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope.	got7fsn_ti	viral budding from outer nuclear membrane during viral capsid envelopment|virus budding from outer nuclear membrane by viral capsid envelopment|outer nuclear membrane viral budding during viral capsid envelopment|virus budding from outer nuclear membrane during viral capsid envelopment	https://github.com/geneontology/go-ontology/issues/20782												biological_process											owl:Class	
GO:1904678	biolink:NamedThing	alpha-aminoacyl-tRNA binding	Binding to an alpha-aminoacyl-tRNA.	got7fsn_ti	aminoacyl-tRNA binding						hjd	2015-09-18T16:44:17Z						molecular_function											owl:Class	
GO:1902372	biolink:NamedThing	positive regulation of tRNA catabolic process	Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.	got7fsn_ti	activation of tRNA catabolic process|up regulation of tRNA catabolic process|up-regulation of tRNA catabolism|up-regulation of tRNA breakdown|upregulation of tRNA catabolic process|positive regulation of tRNA degradation|positive regulation of tRNA catabolism|up regulation of tRNA breakdown|upregulation of tRNA degradation|up regulation of tRNA catabolism|activation of tRNA degradation|positive regulation of tRNA breakdown|upregulation of tRNA catabolism|up-regulation of tRNA catabolic process|up regulation of tRNA degradation|activation of tRNA breakdown|upregulation of tRNA breakdown|activation of tRNA catabolism|up-regulation of tRNA degradation						bf	2013-08-22T15:08:29Z						biological_process											owl:Class	
GO:0023067	biolink:NamedThing	obsolete signal transmission via lymphatic system	OBSOLETE. The process in which a signal is conveyed via the lymphatic system.	got7fsn_ti	signal transmission via lymphatic system				This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0009166	biolink:NamedThing	nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).	got7fsn_ti	nucleotide catabolism|nucleotide degradation|nucleotide breakdown													biological_process											owl:Class	
GO:0009351	biolink:NamedThing	obsolete dihydrolipoamide S-acyltransferase complex	OBSOLETE. An enzyme complex that catalyzes the transfer of an acyl group from coenzyme A to dihydrolipoamide.	got7fsn_ti	dihydrolipoamide S-acyltransferase complex				This term was made obsolete because dihydrolipoamide S-acyltransferase activity resides in a single polypeptide.					True				cellular_component											owl:Class	
GO:0100029	biolink:NamedThing	obsolete regulation of histone modification by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone modification.	got7fsn_ti					This term was obsoleted because it describes a process that does not exist.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1900086	biolink:NamedThing	positive regulation of peptidyl-tyrosine autophosphorylation	Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.	got7fsn_ti	activation of peptidyl-tyrosine autophosphorylation|up regulation of peptidyl-tyrosine autophosphorylation|upregulation of peptidyl-tyrosine autophosphorylation|upregulation of receptor tyrosine kinase autophosphorylation|up regulation of receptor tyrosine kinase autophosphorylation|positive regulation of tyrosine autophosphorylation|positive regulation of receptor tyrosine kinase autophosphorylation|upregulation of tyrosine autophosphorylation|up regulation of tyrosine autophosphorylation|up-regulation of tyrosine autophosphorylation|activation of receptor tyrosine kinase autophosphorylation|activation of tyrosine autophosphorylation|up-regulation of peptidyl-tyrosine autophosphorylation|up-regulation of receptor tyrosine kinase autophosphorylation						bf	2012-02-03T10:17:15Z						biological_process											owl:Class	
GO:1902845	biolink:NamedThing	negative regulation of mitotic spindle elongation	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.	got7fsn_ti	down-regulation of mitotic spindle elongation|downregulation of spindle elongation during mitosis|inhibition of mitotic spindle elongation|down regulation of spindle elongation during mitosis|down regulation of mitotic spindle elongation|inhibition of spindle elongation during mitosis|downregulation of mitotic spindle elongation|negative regulation of spindle elongation during mitosis|down-regulation of spindle elongation during mitosis						vw	2014-04-02T08:43:28Z						biological_process											owl:Class	
GO:0085006	biolink:NamedThing	obsolete interaction with host mediated by symbiont secreted substance released from symbiont-containing vacuole	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via a symbiont-containing vacuole, a specialized sac within the host in which the symbiont resides. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with host mediated by symbiont secreted substance released from parasitophorous vacuole				This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:00:56Z		True				biological_process											owl:Class	
GO:0002090	biolink:NamedThing	regulation of receptor internalization	Any process that modulates the frequency, rate or extent of receptor internalization.	got7fsn_ti														biological_process											owl:Class	
GO:1904241	biolink:NamedThing	positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.	got7fsn_ti	up-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|positive regulation of p97-Ufd1-Npl4 complex assembly|activation of p97-Ufd1-Npl4 complex formation|up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|activation of p97-Ufd1-Npl4 complex assembly|up-regulation of p97-Ufd1-Npl4 complex formation|up-regulation of p97-Ufd1-Npl4 complex assembly|positive regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|activation of VCP-NPL4-UFD1 AAA ATPase complex assembly|positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|upregulation of p97-Ufd1-Npl4 complex assembly|up regulation of p97-Ufd1-Npl4 complex assembly|positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|positive regulation of p97-Ufd1-Npl4 complex formation|up-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|up regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|activation of VCP-NPL4-UFD1 AAA ATPase complex formation|activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|upregulation of p97-Ufd1-Npl4 complex formation|upregulation of VCP-NPL4-UFD1 AAA ATPase complex formation|up regulation of p97-Ufd1-Npl4 complex formation|up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|upregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly						bf	2015-05-18T09:50:34Z						biological_process											owl:Class	
GO:1904012	biolink:NamedThing	obsolete platinum binding	OBSOLETE. Binding to platinum.	got7fsn_ti					The reason for obsoletion is that binding to platinum does not have physiological relevance.		sl	2015-03-06T19:07:37Z		True				molecular_function											owl:Class	
GO:1902029	biolink:NamedThing	positive regulation of histone H3-K18 acetylation	Any process that activates or increases the frequency, rate or extent of histone H3-K18 acetylation.	got7fsn_ti	upregulation of histone H3 acetylation at K18|positive regulation of histone H3K18 acetylation|activation of histone H3K18 acetylation|activation of histone H3 acetylation at K18|up-regulation of histone H3-K18 acetylation|activation of histone H3-K18 acetylation|up regulation of histone H3-K18 acetylation|up-regulation of histone H3 acetylation at K18|up-regulation of histone H3K18 acetylation|positive regulation of histone H3 acetylation at K18|upregulation of histone H3K18 acetylation|upregulation of histone H3-K18 acetylation|up regulation of histone H3K18 acetylation|up regulation of histone H3 acetylation at K18						jl	2013-03-28T20:17:44Z						biological_process											owl:Class	
GO:0005039	biolink:NamedThing	obsolete death receptor-associated factor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	death receptor-associated factor activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005123|GO:0005515				True				molecular_function											owl:Class	
GO:1905112	biolink:NamedThing	obsolete regulation of centromere clustering at the mitotic nuclear envelope	OBSOLETE. Any process that modulates the frequency, rate or extent of centromere clustering at the nuclear envelope.	got7fsn_ti	regulation of kinetochore localization at spindle pole body|regulation of kinetochore clustering at spindle pole body|regulation of kinetochore clustering at SPB|regulation of kinetochore clustering at the old mitotic spindle pole body|regulation of rabl configuration|regulation of centromere clustering at the nuclear periphery|regulation of centromere-SPB clustering				This term was obsoleted because it represented a phenotype.		al	2016-04-06T16:25:41Z		True				biological_process											owl:Class	
GO:2000354	biolink:NamedThing	regulation of ovarian follicle development	Any process that modulates the frequency, rate or extent of ovarian follicle development.	got7fsn_ti	regulation of follicular phase						yaf	2011-02-03T02:01:28Z						biological_process											owl:Class	
GO:1900670	biolink:NamedThing	regulation of F-9775A biosynthetic process	Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process.	got7fsn_ti	regulation of F-9775A synthesis|regulation of F-9775A anabolism|regulation of F-9775A formation|regulation of F-9775A biosynthesis						di	2012-05-22T04:24:09Z						biological_process											owl:Class	
GO:1905714	biolink:NamedThing	obsolete mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium ion concentration	OBSOLETE. Any mitochondrial calcium release that is involved in regulation of presynaptic cytosolic calcium ion concentration.	got7fsn_ti	calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration|mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium levels				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2016-11-23T15:56:01Z		True				biological_process											owl:Class	
GO:0005800	biolink:NamedThing	obsolete COPII vesicle	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	COPII vesicle				This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.	GO:0030134				True				cellular_component											owl:Class	
GO:1902046	biolink:NamedThing	positive regulation of Fas signaling pathway	Any process that activates or increases the frequency, rate or extent of Fas signaling pathway.	got7fsn_ti	up-regulation of CD95 signaling pathway|positive regulation of Fas-FasL signaling pathway|positive regulation of Fas receptor signaling pathway|activation of Apo-1 signaling pathway|positive regulation of FasL signaling pathway|activation of FAS ligand-Fas signaling pathway|activation of CD95 signaling pathway|positive regulation of CD95 signaling pathway|up regulation of Fas receptor signaling pathway|upregulation of Fas-FasL signaling pathway|activation of FasR signaling pathway|activation of Fas receptor signaling pathway|activation of Fas-FasL signaling pathway|upregulation of CD95 signaling pathway|upregulation of FasR signaling pathway|up-regulation of Fas-FasL signaling pathway|upregulation of FasL signaling pathway|up-regulation of FAS ligand-Fas signaling pathway|up regulation of FAS ligand-Fas signaling pathway|up regulation of Apo-1 signaling pathway|up regulation of Fas signaling pathway|upregulation of Fas signaling pathway|up-regulation of Apo-1 signaling pathway|activation of FasL signaling pathway|positive regulation of FasR signaling pathway|up regulation of Fas-FasL signaling pathway|up-regulation of Fas receptor signaling pathway|up-regulation of FasL signaling pathway|upregulation of Fas receptor signaling pathway|up regulation of CD95 signaling pathway|positive regulation of Apo-1 signaling pathway|up regulation of FasL signaling pathway|up-regulation of Fas signaling pathway|activation of Fas signaling pathway|positive regulation of FAS ligand-Fas signaling pathway|upregulation of Apo-1 signaling pathway|upregulation of FAS ligand-Fas signaling pathway|up regulation of FasR signaling pathway|up-regulation of FasR signaling pathway						lb	2013-04-03T07:21:33Z						biological_process											owl:Class	
GO:0023066	biolink:NamedThing	obsolete signal transmission via vascular system	OBSOLETE. The process in which a signal is conveyed via the vascular system.	got7fsn_ti	signal transmission via vascular system				This term was made obsolete because the meaning of the term is ambiguous.	GO:0010232|GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1901307	biolink:NamedThing	positive regulation of spermidine biosynthetic process	Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process.	got7fsn_ti	activation of spermidine anabolism|positive regulation of spermidine formation|upregulation of spermidine biosynthesis|up-regulation of spermidine formation|up regulation of spermidine formation|upregulation of spermidine biosynthetic process|up-regulation of spermidine biosynthetic process|up-regulation of spermidine biosynthesis|positive regulation of spermidine biosynthesis|positive regulation of spermidine anabolism|up regulation of spermidine synthesis|up regulation of spermidine anabolism|activation of spermidine synthesis|activation of spermidine biosynthetic process|upregulation of spermidine synthesis|up-regulation of spermidine synthesis|upregulation of spermidine anabolism|activation of spermidine formation|upregulation of spermidine formation|up-regulation of spermidine anabolism|positive regulation of spermidine synthesis|activation of spermidine biosynthesis|up regulation of spermidine biosynthesis|up regulation of spermidine biosynthetic process						pm	2012-08-21T14:02:58Z						biological_process											owl:Class	
GO:0075090	biolink:NamedThing	obsolete modulation by host of symbiont signal transduction mediated by G-protein alpha subunit	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:2000395	biolink:NamedThing	regulation of ubiquitin-dependent endocytosis	Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis.	got7fsn_ti	regulation of ubiquitin-mediated endocytosis						mah	2011-02-22T11:24:52Z						biological_process											owl:Class	
GO:1903174	biolink:NamedThing	fatty alcohol catabolic process	The chemical reactions and pathways resulting in the breakdown of fatty alcohol.	got7fsn_ti	fatty alcohol catabolism|fatty alcohol breakdown|fatty alcohol degradation						tt	2014-07-14T01:51:48Z						biological_process											owl:Class	
GO:0001083	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase II basal transcription factor binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	RNA polymerase II basal transcription factor binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2010-10-27T04:12:55Z		True				molecular_function											owl:Class	
GO:0071870	biolink:NamedThing	cellular response to catecholamine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.	got7fsn_ti							mah	2010-09-13T02:54:50Z						biological_process											owl:Class	
GO:0010892	biolink:NamedThing	positive regulation of mitochondrial translation in response to stress	Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress.	got7fsn_ti														biological_process											owl:Class	
GO:1905487	biolink:NamedThing	negative regulation of anterior/posterior axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance.	got7fsn_ti	inhibition of anterior/posterior axon pathfinding|down regulation of anterior/posterior axon pathfinding|inhibition of anterior/posterior axon guidance|downregulation of anterior-posterior axon guidance|down regulation of anterior/posterior axon guidance|downregulation of anterior/posterior axon guidance|down-regulation of anterior/posterior axon guidance|down regulation of anterior-posterior axon guidance|downregulation of anterior/posterior axon pathfinding|down-regulation of anterior/posterior axon pathfinding|negative regulation of anterior-posterior axon guidance|inhibition of anterior-posterior axon guidance|negative regulation of anterior/posterior axon pathfinding|down-regulation of anterior-posterior axon guidance						hbye	2016-09-23T13:18:41Z						biological_process											owl:Class	
GO:0048610	biolink:NamedThing	obsolete cellular process involved in reproduction	OBSOLETE. A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism.	got7fsn_ti	cellular process involved in reproduction|reproductive cellular process				This process was made obsolete because we felt it not provide a particularly useful classification, and its very broad logical definition caused regular problems in our inference pipelines.					True				biological_process											owl:Class	
GO:0016299	biolink:NamedThing	obsolete regulator of G-protein signaling activity	OBSOLETE. Inhibits signal transduction the GTPase activity of G-protein alpha subunits, thereby driving them into their inactive GDP-bound form.	got7fsn_ti	regulator of G protein signaling activity|regulator of G-protein signaling activity|regulator of G protein signalling activity|regulator of G-protein signalling activity|RGS				This term was made obsolete because it refers to a combination of a function and a process.	GO:0045744|GO:0034260|GO:0005095				True				molecular_function											owl:Class	
GO:0046157	biolink:NamedThing	siroheme catabolic process	The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.	got7fsn_ti	siroheme degradation|sirohaem catabolic process|sirohaem catabolism|siroheme catabolism|siroheme breakdown													biological_process											owl:Class	
GO:0075235	biolink:NamedThing	obsolete modulation of zoospore movement on or near host	OBSOLETE. Any process that modulates the frequency, rate or extent of zoospore movement on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of zoospore motility on or near host				This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:1901211	biolink:NamedThing	negative regulation of cardiac chamber formation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation.	got7fsn_ti	down-regulation of heart chamber formation|downregulation of heart chamber formation|down regulation of heart chamber formation|down-regulation of cardiac chamber formation|negative regulation of heart chamber formation|inhibition of cardiac chamber formation|downregulation of cardiac chamber formation|inhibition of heart chamber formation|down regulation of cardiac chamber formation						rl	2012-07-31T07:18:57Z						biological_process											owl:Class	
GO:0032771	biolink:NamedThing	regulation of tyrosinase activity	Any process that modulates the activity of a tyrosinase enzyme.	got7fsn_ti	regulation of monophenol monooxygenase activity|regulation of monophenol oxygenase activity	https://github.com/geneontology/go-ontology/issues/21024												biological_process											owl:Class	
GO:1904849	biolink:NamedThing	positive regulation of cell chemotaxis to fibroblast growth factor	Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.	got7fsn_ti	activation of cell chemotaxis to fibroblast growth factor|up-regulation of cell chemotaxis to fibroblast growth factor|upregulation of cell chemotaxis to fibroblast growth factor|up regulation of cell chemotaxis to fibroblast growth factor						rph	2015-12-10T12:04:16Z						biological_process											owl:Class	
GO:0062090	biolink:NamedThing	positive regulation of taurine biosynthetic process	Any process that activates or increases the frequency, rate or extent of taurine biosynthesis.	got7fsn_ti							dph	2018-11-07T14:10:58Z						biological_process											owl:Class	
GO:1902119	biolink:NamedThing	regulation of meiotic spindle elongation	Any process that modulates the frequency, rate or extent of meiotic spindle elongation.	got7fsn_ti	regulation of spindle elongation during meiosis						al	2013-05-15T15:15:48Z						biological_process											owl:Class	
GO:2000745	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation	OBSOLETE. Any positive regulation of transcription from RNA polymerase III promoter that is involved in smooth muscle cell differentiation.	got7fsn_ti	upregulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol III promoter of nonstriated muscle cell differentiation|activation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|up regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|activation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|stimulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|up-regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|upregulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation|positive regulation of transcription from Pol III promoter of smooth muscle cell differentiation|up regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|up-regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|stimulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation				This term was made obsolete because it was added in error.	GO:0048665|GO:0051145	bf	2011-06-15T10:03:19Z		True				biological_process											owl:Class	
GO:2000579	biolink:NamedThing	obsolete positive regulation of microtubule motor activity, minus-end-directed	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.	got7fsn_ti	positive regulation of ATP-dependent microtubule motor activity, minus-end-directed|positive regulation of minus-end-directed kinesin ATPase activity|positive regulation of minus-end-directed microtubule motor activity|positive regulation of kinesin ATP phosphohydrolase (minus-end-directed)	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140660	bf	2011-04-05T08:38:01Z		True				biological_process											owl:Class	
GO:1901059	biolink:NamedThing	p-hydroxyphenyl lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin.	got7fsn_ti	p-hydroxyphenyl lignin degradation|H-lignin catabolic process|p-hydroxyphenyl lignin catabolism|p-hydroxyphenyl lignin breakdown						tt	2012-06-29T12:32:17Z						biological_process											owl:Class	
GO:0006854	biolink:NamedThing	obsolete ATP/ADP exchange	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ATP/ADP exchange			GO:0005471	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:0034111	biolink:NamedThing	negative regulation of homotypic cell-cell adhesion	Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.	got7fsn_ti														biological_process											owl:Class	
GO:0005567	biolink:NamedThing	obsolete cytosolic ribosomal RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytosolic ribosomal RNA				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0052557	biolink:NamedThing	obsolete positive regulation by organism of symbiont immune response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of symbiont immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1904472	biolink:NamedThing	positive regulation of endothelin production	Any process that activates or increases the frequency, rate or extent of endothelin production.	got7fsn_ti	upregulation of endothelin-1 secretion|positive regulation of EDN2 secretion|up-regulation of EDN1 secretion|up-regulation of endothelin secretion|up regulation of endothelin-1 secretion|up regulation of endothelin secretion|positive regulation of endothelin-1 secretion|upregulation of EDN2 secretion|positive regulation of endothelin-3 secretion|positive regulation of endothelin secretion|up-regulation of EDN2 secretion|activation of endothelin-1 secretion|activation of EDN2 secretion|activation of endothelin secretion|upregulation of EDN1 secretion|activation of EDN3 secretion|positive regulation of EDN3 secretion|positive regulation of EDN1 secretion|positive regulation of endothelin-2 secretion|activation of endothelin-2 secretion|up-regulation of endothelin-2 secretion|upregulation of endothelin-3 secretion|activation of EDN1 secretion|up regulation of EDN2 secretion|upregulation of EDN3 secretion|up-regulation of EDN3 secretion|up regulation of endothelin-3 secretion|up regulation of endothelin-2 secretion|upregulation of endothelin-2 secretion|up-regulation of endothelin-1 secretion|up-regulation of endothelin-3 secretion|up regulation of EDN3 secretion|upregulation of endothelin secretion|up regulation of EDN1 secretion|activation of endothelin-3 secretion						sl	2015-07-09T19:58:10Z						biological_process											owl:Class	
GO:0039544	biolink:NamedThing	obsolete suppression by virus of host RIG-I activity by RIG-I proteolysis	OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction.	got7fsn_ti	cleavage of RIG-I by viral proteinase|inhibition by virus of host RIG-I activity by RIG-I proteolysis				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-18T02:30:29Z		True				biological_process											owl:Class	
GO:0046452	biolink:NamedThing	dihydrofolate metabolic process	The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate.	got7fsn_ti	dihydrofolate reduction|dihydrofolate metabolism													biological_process											owl:Class	
GO:1904410	biolink:NamedThing	negative regulation of secretory granule organization	Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization.	got7fsn_ti	negative regulation of secretory granule organization and biogenesis|inhibition of secretory granule organization|down regulation of secretory granule organisation|downregulation of secretory granule organization and biogenesis|down regulation of secretory granule organization and biogenesis|downregulation of secretory granule organisation|down-regulation of secretory granule organization and biogenesis|downregulation of secretory granule organization|negative regulation of secretory granule organisation|down-regulation of secretory granule organisation|inhibition of secretory granule organization and biogenesis|down regulation of secretory granule organization|down-regulation of secretory granule organization|inhibition of secretory granule organisation						sl	2015-06-25T19:40:49Z						biological_process											owl:Class	
GO:2000659	biolink:NamedThing	regulation of interleukin-1-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway.	got7fsn_ti	regulation of interleukin-1 alpha-mediated signaling pathway|regulation of IL-1-mediated signaling pathway|regulation of IL-1 beta-mediated signaling pathway|regulation of IL-1 alpha-mediated signaling pathway|regulation of interleukin-1-mediated signalling pathway|regulation of interleukin-1 beta-mediated signaling pathway						dph	2011-05-03T07:13:31Z						biological_process											owl:Class	
GO:0031148	biolink:NamedThing	DIF-1 biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.	got7fsn_ti	1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one formation|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthesis|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one synthesis|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one anabolism|DIF-1 biosynthesis|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthetic process													biological_process											owl:Class	
GO:0006228	biolink:NamedThing	UTP biosynthetic process	The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate.	got7fsn_ti	UTP formation|UTP biosynthesis|UTP anabolism|UTP synthesis													biological_process											owl:Class	
GO:0100026	biolink:NamedThing	positive regulation of DNA repair by transcription from RNA polymerase II promoter	Any transcription from RNA polymerase II promoter process that positively regulates DNA repair.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
GO:1903727	biolink:NamedThing	positive regulation of phospholipid metabolic process	Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process.	got7fsn_ti	positive regulation of phospholipid metabolism|up regulation of phospholipid metabolic process|up-regulation of phospholipid metabolism|up-regulation of phospholipid metabolic process|activation of phospholipid metabolism|up regulation of phospholipid metabolism|upregulation of phospholipid metabolism|upregulation of phospholipid metabolic process|activation of phospholipid metabolic process						sl	2014-12-09T20:49:44Z						biological_process											owl:Class	
GO:0120261	biolink:NamedThing	regulation of heterochromatin organization	Any process that modulates the frequency, rate, extent or location of heterochromatin organization.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20020					krc	2020-09-29T20:00:04Z						biological_process											owl:Class	
GO:0018314	biolink:NamedThing	obsolete protein-pyrroloquinoline-quinone linkage	OBSOLETE. The covalent cross-linking of pyrroloquinoline-quinone to peptidyl-glutamic acid and peptidyl-tyrosine.	got7fsn_ti	protein-pyrroloquinoline-quinone linkage			GO:0006464						True				biological_process											owl:Class	
GO:1901574	biolink:NamedThing	obsolete chemical substance biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of chemical substance.	got7fsn_ti	chemical substance biosynthesis|chemical substance anabolism|chemical substance synthesis|chemical substance biosynthetic process|chemical substance formation				This term was obsoleted at the TermGenie Gatekeeper stage.		pr	2012-11-04T18:10:40Z		True				biological_process											owl:Class	
GO:0048691	biolink:NamedThing	positive regulation of axon extension involved in regeneration	Any process that activates, maintains or increases the rate of axon extension involved in regeneration.	got7fsn_ti	upregulation of axon extension involved in regeneration|stimulation of axon extension involved in regeneration|activation of axon extension involved in regeneration|up regulation of axon extension involved in regeneration|up-regulation of axon extension involved in regeneration													biological_process											owl:Class	
GO:1901609	biolink:NamedThing	negative regulation of vesicle transport along microtubule	Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.	got7fsn_ti	down regulation of microtubule-based vesicle localization|down-regulation of vesicle transport along microtubule|downregulation of microtubule-based vesicle localization|downregulation of vesicle transport along microtubule|inhibition of microtubule-based vesicle localization|down regulation of vesicle transport along microtubule|negative regulation of microtubule-based vesicle localization|down-regulation of microtubule-based vesicle localization|inhibition of vesicle transport along microtubule						hjd	2012-11-08T21:49:48Z						biological_process											owl:Class	
GO:0046477	biolink:NamedThing	glycosylceramide catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.	got7fsn_ti	glycosylceramide catabolism|glycosylceramide degradation|glycosylceramide breakdown													biological_process											owl:Class	
GO:0006244	biolink:NamedThing	pyrimidine nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine nucleotide breakdown|pyrimidine nucleotide degradation|pyrimidine nucleotide catabolism													biological_process											owl:Class	
GO:0019950	biolink:NamedThing	obsolete SMT3-dependent protein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein.	got7fsn_ti	SMT3-dependent protein degradation|SMT3-dependent protein breakdown|SMT3-dependent protein catabolism				See issue #21890. SMT3 protein mod is sumoylation and does not always lead to degradation.					True	GO:0019946			biological_process											owl:Class	
GO:1901556	biolink:NamedThing	response to candesartan	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus.	got7fsn_ti							hp	2012-11-02T09:46:13Z						biological_process											owl:Class	
GO:2000203	biolink:NamedThing	regulation of ribosomal large subunit export from nucleus	Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus.	got7fsn_ti	regulation of ribosomal large subunit-nucleus export|regulation of ribosomal large subunit export from cell nucleus|regulation of ribosomal large subunit transport from nucleus to cytoplasm|regulation of 60S ribosomal subunit export from nucleus|regulation of ribosomal large subunit export out of nucleus|regulation of 50S ribosomal subunit export from nucleus						mah	2010-10-26T10:52:36Z						biological_process											owl:Class	
GO:0033087	biolink:NamedThing	negative regulation of immature T cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0006101	biolink:NamedThing	citrate metabolic process	The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle.	got7fsn_ti	citrate metabolism													biological_process											owl:Class	
GO:0033182	biolink:NamedThing	regulation of histone ubiquitination	Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.	got7fsn_ti														biological_process											owl:Class	
GO:2000327	biolink:NamedThing	obsolete positive regulation of nuclear receptor transcription coactivator activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.	got7fsn_ti	positive regulation of ligand-dependent nuclear receptor transcription co-activator activity|positive regulation of ligand-dependent nuclear receptor transcription coactivator activity				This term was obsoleted because it represents a molecular function.	GO:0030374	vk	2011-01-18T06:30:23Z		True				biological_process											owl:Class	
GO:2000783	biolink:NamedThing	negative regulation of establishment of cell polarity regulating cell shape	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape.	got7fsn_ti							mah	2011-06-23T12:17:44Z						biological_process											owl:Class	
GO:1904278	biolink:NamedThing	positive regulation of wax biosynthetic process	Any process that activates or increases the frequency, rate or extent of wax biosynthetic process.	got7fsn_ti	up regulation of wax biosynthesis|up-regulation of wax synthesis|up-regulation of wax formation|positive regulation of wax synthesis|upregulation of wax formation|activation of wax formation|positive regulation of wax anabolism|up regulation of wax formation|activation of wax biosynthetic process|upregulation of wax biosynthetic process|positive regulation of wax formation|up-regulation of wax biosynthetic process|upregulation of wax synthesis|activation of wax anabolism|up-regulation of wax biosynthesis|positive regulation of wax biosynthesis|activation of wax synthesis|upregulation of wax anabolism|activation of wax biosynthesis|up regulation of wax synthesis|up-regulation of wax anabolism|up regulation of wax biosynthetic process|up regulation of wax anabolism|upregulation of wax biosynthesis						tb	2015-06-03T17:20:19Z						biological_process											owl:Class	
GO:1903998	biolink:NamedThing	regulation of eating behavior	Any process that modulates the frequency, rate or extent of eating behavior.	got7fsn_ti	regulation of eating behaviour						sl	2015-03-05T20:40:22Z						biological_process											owl:Class	
GO:1900453	biolink:NamedThing	negative regulation of long-term synaptic depression	Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression.	got7fsn_ti	inhibition of LTD|downregulation of long term synaptic depression|down regulation of long term synaptic depression|down-regulation of LTD|inhibition of long term synaptic depression|down-regulation of long term synaptic depression|down regulation of LTD|down-regulation of long term depression|inhibition of long term depression|downregulation of long term depression|negative regulation of LTD|down regulation of long term depression|downregulation of LTD|negative regulation of long term depression|negative regulation of long term synaptic depression						rl	2012-04-27T03:55:14Z						biological_process											owl:Class	
GO:1905507	biolink:NamedThing	obsolete cytoplasmic sequestering of protein involved in mitotic G2 DNA damage checkpoint	OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic G2 DNA damage checkpoint.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		vw	2016-09-28T12:20:28Z		True				biological_process											owl:Class	
GO:0052048	biolink:NamedThing	obsolete interaction with host via secreted substance	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with host via secreted substance during symbiotic interaction|interaction with host via secreted substance involved in symbiotic interaction				This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True				biological_process											owl:Class	
GO:1901980	biolink:NamedThing	positive regulation of inward rectifier potassium channel activity	Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity.	got7fsn_ti	activation of inward rectifier potassium channel activity|up regulation of Kir channel activity|up-regulation of inward rectifier potassium channel activity|activation of Kir channel activity|upregulation of inward rectifier potassium channel activity|up regulation of inward rectifier potassium channel activity|positive regulation of Kir channel activity|upregulation of Kir channel activity|up-regulation of Kir channel activity						tb	2013-03-12T18:21:17Z						biological_process											owl:Class	
GO:1905195	biolink:NamedThing	obsolete regulation of ATPase activity, uncoupled	OBSOLETE. Any process that modulates the frequency, rate or extent of ATPase activity, uncoupled.	got7fsn_ti	regulation of adenylpyrophosphatase activity				The reason for obsoletion is that the there is no convincing example of a protein with this function.		al	2016-05-12T08:01:20Z		True				biological_process											owl:Class	
GO:1902206	biolink:NamedThing	negative regulation of interleukin-2-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway.	got7fsn_ti	down-regulation of IL-2-mediated signaling pathway|inhibition of IL-2-mediated signaling pathway|down-regulation of interleukin-2-mediated signalling pathway|negative regulation of interleukin-2-mediated signalling pathway|inhibition of interleukin-2-mediated signalling pathway|down regulation of interleukin-2-mediated signalling pathway|down regulation of interleukin-2-mediated signaling pathway|downregulation of interleukin-2-mediated signaling pathway|downregulation of interleukin-2-mediated signalling pathway|down-regulation of interleukin-2-mediated signaling pathway|downregulation of IL-2-mediated signaling pathway|negative regulation of IL-2-mediated signaling pathway|down regulation of IL-2-mediated signaling pathway|inhibition of interleukin-2-mediated signaling pathway						lb	2013-06-11T07:34:45Z						biological_process											owl:Class	
GO:0030460	biolink:NamedThing	obsolete nuclear translocation of MAPK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nuclear translocation of MAPK (mating sensu Fungi)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0000364	biolink:NamedThing	obsolete second U2-type spliceosomal transesterification activity	OBSOLETE. Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.	got7fsn_ti	3'-splice site cleavage, exon ligation|second U2-type spliceosomal transesterification activity			GO:0000386	This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.					True				molecular_function											owl:Class	
GO:1901287	biolink:NamedThing	iron-sulfur-molybdenum cofactor catabolic process	The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor.	got7fsn_ti	iron-molybdenum breakdown|iron-sulfur-molybdenum cofactor breakdown|FeMo-co breakdown|iron-molybdenum degradation|iron-molybdenum catabolism|FeMo-co catabolism|iron-molybdenum catabolic process|iron-sulfur-molybdenum cofactor catabolism|FeMo-co degradation|iron-sulfur-molybdenum cofactor degradation|FeMo-co catabolic process						yaf	2012-08-17T15:39:36Z						biological_process											owl:Class	
GO:1902691	biolink:NamedThing	respiratory basal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell.	got7fsn_ti	airway basal cell differentiation				Changes in the lineage choice of ABCs or their undifferentiated daughters might contribute to the mucous cell hyperplasia, metaplasia or squamous metaplasia seen in many respiratory disorders		cjm	2014-02-13T23:41:24Z						biological_process											owl:Class	
GO:1904779	biolink:NamedThing	regulation of protein localization to centrosome	Any process that modulates the frequency, rate or extent of protein localization to centrosome.	got7fsn_ti	regulation of protein localisation to centrosome				An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype).		es	2015-10-30T11:54:30Z						biological_process											owl:Class	
GO:2000460	biolink:NamedThing	obsolete regulation of eukaryotic cell surface binding	OBSOLETE. Any process that modulates the frequency, rate or extent of eukaryotic cell surface binding.	got7fsn_ti	regulation of eukaryotic cell surface binding				This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion.	GO:0031347|GO:1900120	yaf	2011-03-04T11:59:52Z		True				biological_process											owl:Class	
GO:0120237	biolink:NamedThing	terminal acetylenic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.	got7fsn_ti	terminal alkyne substituted compound anabolism|terminal alkyne substituted compound synthesis|terminal alkyne substituted compound biosynthetic process|terminal alkyne substituted compound biosynthesis|terminal alkyne substituted compound anabolic process	https://github.com/geneontology/go-ontology/issues/17763					krc	2020-07-17T20:19:10Z						biological_process											owl:Class	
GO:1903698	biolink:NamedThing	positive regulation of microvillus assembly	Any process that activates or increases the frequency, rate or extent of microvillus assembly.	got7fsn_ti	up regulation of microvillus biogenesis|up-regulation of microvillus assembly|upregulation of microvillus assembly|positive regulation of microvillus biogenesis|up regulation of microvillus assembly|activation of microvillus assembly|upregulation of microvillus biogenesis|up-regulation of microvillus biogenesis|activation of microvillus biogenesis						als	2014-12-03T11:45:17Z						biological_process											owl:Class	
GO:1904136	biolink:NamedThing	regulation of convergent extension involved in notochord morphogenesis	Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis.	got7fsn_ti							dph	2015-04-10T21:21:30Z						biological_process											owl:Class	
GO:0048782	biolink:NamedThing	negative regulation of cyanophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation.	got7fsn_ti	downregulation of cyanophore differentiation|down-regulation of cyanophore differentiation|down regulation of cyanophore differentiation|inhibition of cyanophore differentiation													biological_process											owl:Class	
GO:1903454	biolink:NamedThing	regulation of androst-4-ene-3,17-dione biosynthetic process	Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.	got7fsn_ti	regulation of androst-4-ene-3,17-dione biosynthesis|regulation of androst-4-ene-3,17-dione anabolism|regulation of androst-4-ene-3,17-dione formation|regulation of androstenedione biosynthetic process|regulation of androst-4-ene-3,17-dione synthesis						mr	2014-09-22T14:36:50Z						biological_process											owl:Class	
GO:0106279	biolink:NamedThing	negative regulation of UDP-N-acetylglucosamine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.	got7fsn_ti	negative regulation of UDP-N-acetylglucosamine synthesis|negative regulation of UDP-GlcNAc biosynthesis|negative regulation of UDP-N-acetylglucosamine formation|negative regulation of UDP-N-acetylglucosamine anabolism|negative regulation of UDP-GlcNAc biosynthetic process|negative regulation of UDP-N-acetylglucosamine biosynthesis						hjd	2020-07-09T17:26:06Z						biological_process											owl:Class	
GO:1902597	biolink:NamedThing	positive regulation of DNA replication origin binding	Any process that activates or increases the frequency, rate or extent of DNA replication origin binding.	got7fsn_ti	up regulation of ARS binding|positive regulation of ARS binding|upregulation of ARS binding|upregulation of DNA replication origin binding|up-regulation of ARS binding|activation of DNA replication origin binding|activation of ARS binding|up-regulation of DNA replication origin binding|up regulation of DNA replication origin binding						mah	2013-12-19T16:19:57Z						biological_process											owl:Class	
GO:0015076	biolink:NamedThing	obsolete heavy metal ion transporter activity	OBSOLETE. Enables the directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	got7fsn_ti	heavy metal ion transporter activity				This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0046873				True				molecular_function											owl:Class	
UBERON:0002082	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904219	biolink:NamedThing	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.	got7fsn_ti	positive regulation of phosphatidylserine synthetase activity|up regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|up regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|positive regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|up regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|upregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up-regulation of phosphatidylserine synthase activity|up regulation of CDP-diglyceride:serine phosphatidyltransferase activity|up-regulation of PS synthase activity|up-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|activation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|activation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|activation of phosphatidylserine synthetase activity|upregulation of phosphatidylserine synthetase activity|upregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|up regulation of PS synthase activity|activation of CDPdiglyceride-serine O-phosphatidyltransferase activity|activation of PS synthase activity|up regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|positive regulation of phosphatidylserine synthase activity|up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up-regulation of phosphatidylserine synthetase activity|upregulation of CDP-diglyceride:serine phosphatidyltransferase activity|upregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|positive regulation of CDP-diglyceride:serine phosphatidyltransferase activity|activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|activation of CDP-diglycerine-serine O-phosphatidyltransferase activity|activation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|upregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|positive regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|up regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|activation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|upregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|positive regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|positive regulation of PS synthase activity|up regulation of phosphatidylserine synthase activity|upregulation of phosphatidylserine synthase activity|up-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|up-regulation of CDP-diglyceride:serine phosphatidyltransferase activity|up regulation of phosphatidylserine synthetase activity|positive regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|activation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|activation of CDP-diglyceride:serine phosphatidyltransferase activity|up regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|activation of CDP-diglyceride-L-serine phosphatidyltransferase activity|positive regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|upregulation of PS synthase activity|up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|activation of phosphatidylserine synthase activity|upregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity				Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate		rl	2015-05-15T08:18:35Z						biological_process											owl:Class	
GO:0030439	biolink:NamedThing	obsolete activation of MAPK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of MAPK during sporulation (sensu Fungi)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:2000772	biolink:NamedThing	regulation of cellular senescence	Any process that modulates the frequency, rate or extent of cellular senescence.	got7fsn_ti							bf	2011-06-22T01:57:04Z						biological_process											owl:Class	
GO:1990961	biolink:NamedThing	xenobiotic detoxification by transmembrane export across the plasma membrane	A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell.	got7fsn_ti	drug transmembrane export	https://github.com/geneontology/go-ontology/issues/17141					sl	2016-06-06T23:47:22Z						biological_process											owl:Class	
GO:0016902	biolink:NamedThing	obsolete oxidoreductase activity, acting on the CH-OH group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, NAD, NADP, oxygen or a quinone or similar compound.	got7fsn_ti	oxidoreductase activity, acting on the CH-OH group of donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016614				True				molecular_function											owl:Class	
GO:0000826	biolink:NamedThing	obsolete inositol pyrophosphate synthase activity	OBSOLETE. Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds.	got7fsn_ti	inositol pyrophosphate synthase activity|inositol diphosphate synthase activity				This term was made obsolete because it is incorrectly defined; 'inositol pyrophosphate' is a inositol derivative to which one (or more) pyrophosphate moieties are attached. 'Inositol pyrophosphate synthase' refers to a class of enzymes that catalyze various different reactions that result in the formation of an IP, so one cannot formulate a general reaction for them.	GO:0052746				True				molecular_function											owl:Class	
GO:1905556	biolink:NamedThing	ciliary vesicle assembly	The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane.	got7fsn_ti	ciliary vesicle formation|CV formation|primary ciliary vesicle assembly|primary ciliary vesicle formation|CV assembly						pr	2016-10-13T09:31:06Z						biological_process											owl:Class	
GO:0098730	biolink:NamedThing	male germline stem cell symmetric division	The symmetric division of a male germline stem cell to produce two male germline stem cells.  An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic.	got7fsn_ti														biological_process											owl:Class	
GO:1901324	biolink:NamedThing	response to trichodermin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.	got7fsn_ti							mah	2012-08-30T10:11:07Z						biological_process											owl:Class	
GO:1905600	biolink:NamedThing	regulation of receptor-mediated endocytosis involved in cholesterol transport	Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.	got7fsn_ti	regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|regulation of receptor-mediated endocytosis of LDL|regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport						pr	2016-10-26T13:01:45Z						biological_process											owl:Class	
GO:2000390	biolink:NamedThing	negative regulation of neutrophil extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation.	got7fsn_ti							mah	2011-02-22T11:08:23Z						biological_process											owl:Class	
GO:0061963	biolink:NamedThing	regulation of entry into reproductive diapause	Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	got7fsn_ti							dph	2018-02-05T15:02:16Z						biological_process											owl:Class	
GO:1902044	biolink:NamedThing	regulation of Fas signaling pathway	Any process that modulates the frequency, rate or extent of Fas signaling pathway.	got7fsn_ti	regulation of Fas-FasL signaling pathway|regulation of FAS ligand-Fas signaling pathway|regulation of Apo-1 signaling pathway|regulation of FasR signaling pathway|regulation of FasL signaling pathway|regulation of Fas receptor signaling pathway|regulation of CD95 signaling pathway						lb	2013-04-03T07:21:23Z						biological_process											owl:Class	
GO:2000149	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.	got7fsn_ti							dph	2010-10-01T07:09:53Z						biological_process											owl:Class	
GO:0009457	biolink:NamedThing	obsolete flavodoxin	OBSOLETE. A group of small electron carriers, characteristic of anaerobic bacteria, photosynthetic bacteria, cyanobacteria and eukaryotic algae. Contain flavin mononucleotide.	got7fsn_ti	flavodoxin			GO:0009055	This term was made obsolete because it represents a class of gene products.					True				molecular_function											owl:Class	
GO:1905480	biolink:NamedThing	positive regulation of glutamate-ammonia ligase activity	Any process that activates or increases the frequency, rate or extent of glutamate-ammonia ligase activity.	got7fsn_ti	upregulation of glutamine synthetase activity|up-regulation of glutamine synthetase activity|up-regulation of L-glutamate:ammonia ligase (ADP-forming)|up regulation of glutamine synthetase activity|activation of glutamate-ammonia ligase activity|upregulation of glutamylhydroxamic synthetase activity|up regulation of L-glutamate:ammonia ligase (ADP-forming)|up regulation of glutamylhydroxamic synthetase activity|up regulation of glutamate-ammonia ligase activity|up-regulation of glutamate-ammonia ligase activity|activation of glutamine synthetase activity|positive regulation of L-glutamine synthetase activity|up-regulation of glutamylhydroxamic synthetase activity|positive regulation of glutamylhydroxamic synthetase activity|activation of L-glutamine synthetase activity|positive regulation of glutamine synthetase activity|upregulation of L-glutamate:ammonia ligase (ADP-forming)|upregulation of glutamate-ammonia ligase activity|up regulation of L-glutamine synthetase activity|activation of glutamylhydroxamic synthetase activity|positive regulation of L-glutamate:ammonia ligase (ADP-forming)|up-regulation of L-glutamine synthetase activity|upregulation of L-glutamine synthetase activity|activation of L-glutamate:ammonia ligase (ADP-forming)						pga	2016-09-22T09:58:50Z						biological_process											owl:Class	
GO:0019270	biolink:NamedThing	aerobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.	got7fsn_ti	aerobactin synthesis|aerobactin formation|aerobactin biosynthesis|aerobactin anabolism											MetaCyc:AEROBACTINSYN-PWY		biological_process											owl:Class	
GO:0048304	biolink:NamedThing	positive regulation of isotype switching to IgG isotypes	Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.	got7fsn_ti	activation of isotype switching to IgG isotypes|positive regulation of isotype switch recombination to IgG isotypes|positive regulation of class switch recombination to IgG isotypes|up regulation of isotype switching to IgG isotypes|positive regulation of class switching to IgG isotypes|stimulation of isotype switching to IgG isotypes|up-regulation of isotype switching to IgG isotypes|upregulation of isotype switching to IgG isotypes													biological_process											owl:Class	
GO:1900448	biolink:NamedThing	obsolete regulation of pyrimidine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		jh	2012-04-27T02:57:38Z		True				biological_process											owl:Class	
GO:0070473	biolink:NamedThing	negative regulation of uterine smooth muscle contraction	Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction.	got7fsn_ti	inhibition of uterine smooth muscle contraction|downregulation of uterine smooth muscle contraction|down-regulation of uterine smooth muscle contraction|negative regulation of myometrial contraction|negative regulation of myometrium contraction|down regulation of uterine smooth muscle contraction|negative regulation of myometrial smooth muscle contraction|uterine smooth muscle relaxation													biological_process											owl:Class	
GO:0008945	biolink:NamedThing	obsolete oligopeptidase B activity	OBSOLETE. Catalysis of the hydrolysis of Arg-Xaa and Lys-Xaa bonds in oligopeptides, even when P1' residue is proline.	got7fsn_ti	protease II activity|Escherichia coli alkaline proteinase II|oligopeptidase B activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0045918	biolink:NamedThing	negative regulation of cytolysis	Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis.	got7fsn_ti	inhibition of cytolysis|down regulation of cytolysis|down-regulation of cytolysis|downregulation of cytolysis													biological_process											owl:Class	
GO:0098941	biolink:NamedThing	anterograde trans-synaptic signaling by trans-synaptic protein complex	Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0075336	biolink:NamedThing	obsolete negative regulation of symbiont adenylate cyclase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0033052	biolink:NamedThing	cyanoamino acid metabolic process	The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group.	got7fsn_ti	cyanoamino acid metabolism													biological_process											owl:Class	
GO:1904515	biolink:NamedThing	positive regulation of TORC2 signaling	Any process that activates or increases the frequency, rate or extent of TORC2 signaling.	got7fsn_ti	upregulation of TORC2 signaling|activation of TORC2 signal transduction|positive regulation of TORC2 signal transduction|activation of TORC2 signaling|up-regulation of TORC2 signaling|up regulation of TORC2 signaling|up-regulation of TORC2 signal transduction|upregulation of TORC2 signal transduction|up regulation of TORC2 signal transduction						al	2015-07-28T16:09:55Z						biological_process											owl:Class	
GO:0010546	biolink:NamedThing	obsolete Hsp90 protein inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the Hsp90 molecular chaperone.	got7fsn_ti	Hsp90 protein inhibitor activity			GO:0051879	This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp90 protein activity'.	GO:0051082|GO:0051787|GO:0006457				True				molecular_function											owl:Class	
GO:1904043	biolink:NamedThing	positive regulation of cystathionine beta-synthase activity	Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity.	got7fsn_ti	upregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up regulation of methylcysteine synthase activity|up regulation of L-serine hydro-lyase (adding homocysteine)|up regulation of beta-thionase activity|positive regulation of serine sulfhydrase activity|activation of cystathionine beta-synthase activity|up-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up-regulation of methylcysteine synthase activity|activation of L-serine hydro-lyase (adding homocysteine)|positive regulation of methylcysteine synthase activity|upregulation of serine sulfhydrylase activity|upregulation of methylcysteine synthase activity|activation of serine sulfhydrylase activity|up-regulation of L-serine hydro-lyase (adding homocysteine)|up-regulation of serine sulfhydrylase activity|up regulation of cystathionine beta-synthase activity|upregulation of serine sulfhydrase activity|up-regulation of serine sulfhydrase activity|upregulation of beta-thionase activity|positive regulation of serine sulfhydrylase activity|up regulation of serine sulfhydrylase activity|up-regulation of beta-thionase activity|activation of beta-thionase activity|positive regulation of beta-thionase activity|positive regulation of L-serine hydro-lyase (adding homocysteine)|positive regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up-regulation of cystathionine beta-synthase activity|upregulation of L-serine hydro-lyase (adding homocysteine)|up regulation of serine sulfhydrase activity|activation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|upregulation of cystathionine beta-synthase activity|activation of serine sulfhydrase activity|activation of methylcysteine synthase activity						hal	2015-03-16T15:52:53Z						biological_process											owl:Class	
GO:0060636	biolink:NamedThing	negative regulation of (1->3)-beta-D-glucan biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.	got7fsn_ti	negative regulation of 1,3-beta-D-glucan biosynthetic process						dph	2009-05-18T03:24:02Z						biological_process											owl:Class	
GO:0075023	biolink:NamedThing	obsolete MAPK-mediated regulation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	mitogen-activated protein kinase-mediated activation of appressorium formation				This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1900150	biolink:NamedThing	regulation of defense response to fungus	Any process that modulates the frequency, rate or extent of defense response to fungus.	got7fsn_ti	regulation of resistance response to pathogenic fungi|regulation of defence response to fungus|regulation of defense response to fungi|regulation of defense response to fungi, incompatible interaction|regulation of defence response to fungi|regulation of resistance response to pathogenic fungus|regulation of response to pathogenic fungus (incompatible interaction)|regulation of defense response to fungus, incompatible interaction						dhl	2012-03-06T10:00:16Z			GO:2000072			biological_process											owl:Class	
GO:0030812	biolink:NamedThing	negative regulation of nucleotide catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.	got7fsn_ti	negative regulation of nucleotide degradation|downregulation of nucleotide catabolic process|negative regulation of nucleotide breakdown|negative regulation of nucleotide catabolism|down-regulation of nucleotide catabolic process|inhibition of nucleotide catabolic process|down regulation of nucleotide catabolic process													biological_process											owl:Class	
GO:1901386	biolink:NamedThing	negative regulation of voltage-gated calcium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.	got7fsn_ti	down regulation of voltage-gated calcium ion channel activity|down-regulation of voltage gated calcium channel activity|downregulation of voltage gated calcium channel activity|negative regulation of dihydropyridine-sensitive calcium channel activity|negative regulation of depolarization-activated voltage-gated calcium channel activity|inhibition of depolarization-activated calcium channel|down regulation of voltage-gated calcium channel activity|down-regulation of depolarization-activated voltage-gated calcium channel activity|inhibition of depolarization-activated voltage-gated calcium channel|inhibition of depolarization-activated voltage-gated calcium channel activity|down-regulation of depolarization-activated voltage-gated calcium channel|down regulation of voltage-dependent calcium channel activity|down-regulation of voltage-sensitive calcium channel|inhibition of voltage-dependent calcium channel activity|downregulation of voltage-sensitive calcium channel|inhibition of voltage-gated calcium channel activity|down regulation of depolarization-activated calcium channel|down-regulation of depolarization-activated calcium channel|inhibition of voltage gated calcium channel activity|down-regulation of dihydropyridine-sensitive calcium channel activity|downregulation of voltage-dependent calcium channel activity|down regulation of depolarization-activated voltage-gated calcium channel activity|down regulation of depolarization-activated voltage-gated calcium channel|negative regulation of depolarization-activated calcium channel|inhibition of depolarization-activated voltage gated calcium channel activity|downregulation of depolarization-activated voltage-gated calcium channel|inhibition of voltage-sensitive calcium channel|inhibition of voltage-gated calcium ion channel activity|down regulation of dihydropyridine-sensitive calcium channel activity|downregulation of depolarization-activated voltage-gated calcium channel activity|down-regulation of voltage-gated calcium ion channel activity|downregulation of voltage-gated calcium channel activity|downregulation of depolarization-activated calcium channel|down-regulation of voltage-dependent calcium channel activity|negative regulation of voltage gated calcium channel activity|negative regulation of voltage-gated calcium ion channel activity|negative regulation of voltage-dependent calcium channel activity|inhibition of dihydropyridine-sensitive calcium channel activity|negative regulation of voltage-sensitive calcium channel|down-regulation of depolarization-activated voltage gated calcium channel activity|downregulation of depolarization-activated voltage gated calcium channel activity|down-regulation of voltage-gated calcium channel activity|negative regulation of depolarization-activated voltage gated calcium channel activity|downregulation of dihydropyridine-sensitive calcium channel activity|down regulation of voltage gated calcium channel activity|downregulation of voltage-gated calcium ion channel activity|negative regulation of depolarization-activated voltage-gated calcium channel|down regulation of depolarization-activated voltage gated calcium channel activity|down regulation of voltage-sensitive calcium channel						vk	2012-10-01T10:35:15Z						biological_process											owl:Class	
GO:0052783	biolink:NamedThing	reuteran metabolic process	The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.	got7fsn_ti							ai	2011-10-04T09:16:35Z						biological_process											owl:Class	
GO:0100038	biolink:NamedThing	obsolete regulation of cellular response to oxidative stress by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cellular response to oxidative stress.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0032974	biolink:NamedThing	amino acid transmembrane export from vacuole	The directed movement of amino acids out of the vacuole, across the vacuolar membrane.	got7fsn_ti	amino acid efflux from vacuole|vacuolar amino acid export													biological_process											owl:Class	
GO:1903720	biolink:NamedThing	negative regulation of I-kappaB phosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation.	got7fsn_ti	down regulation of inhibitor of kappaB phosphorylation|down-regulation of IKB phosphorylation|down regulation of I-kappaB phosphorylation|negative regulation of IkappaB phosphorylation|down-regulation of inhibitor of kappaB phosphorylation|down-regulation of I-kappaB phosphorylation|negative regulation of inhibitor of kappaB phosphorylation|down regulation of inhibitor of NF-kappaB phosphorylation|inhibition of I-kappaB phosphorylation|downregulation of IkappaB phosphorylation|downregulation of I-kappaB phosphorylation|down regulation of IkappaB phosphorylation|inhibition of inhibitor of kappaB phosphorylation|downregulation of inhibitor of NF-kappaB phosphorylation|down-regulation of inhibitor of NF-kappaB phosphorylation|negative regulation of inhibitor of NF-kappaB phosphorylation|inhibition of inhibitor of NF-kappaB phosphorylation|downregulation of inhibitor of kappaB phosphorylation|negative regulation of IKB phosphorylation|inhibition of IkappaB phosphorylation|down regulation of IKB phosphorylation|downregulation of IKB phosphorylation|inhibition of IKB phosphorylation|down-regulation of IkappaB phosphorylation						lb	2014-12-08T15:45:16Z						biological_process											owl:Class	
GO:1904188	biolink:NamedThing	negative regulation of transformation of host cell by virus	Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus.	got7fsn_ti	downregulation of transformation of host cell by virus|downregulation of viral transformation of host cell|down regulation of viral transformation|negative regulation of viral transformation of host cell|inhibition of viral transformation|negative regulation of viral transformation|inhibition of viral transformation of host cell|down-regulation of viral transformation|inhibition of transformation of host cell by virus|downregulation of viral transformation|down regulation of viral transformation of host cell|down regulation of transformation of host cell by virus|down-regulation of viral transformation of host cell|down-regulation of transformation of host cell by virus						pga	2015-05-05T15:30:04Z						biological_process											owl:Class	
GO:1904478	biolink:NamedThing	regulation of intestinal absorption	Any process that modulates the frequency, rate or extent of intestinal absorption.	got7fsn_ti							rl	2015-07-13T15:58:47Z						biological_process											owl:Class	
GO:0048631	biolink:NamedThing	regulation of skeletal muscle tissue growth	Any process that modulates the frequency, rate or extent of skeletal muscle growth.	got7fsn_ti														biological_process											owl:Class	
GO:0046644	biolink:NamedThing	negative regulation of gamma-delta T cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation.	got7fsn_ti	down regulation of gamma-delta T cell activation|negative regulation of gamma-delta T-cell activation|negative regulation of gamma-delta T-lymphocyte activation|inhibition of gamma-delta T cell activation|negative regulation of gamma-delta T lymphocyte activation|down-regulation of gamma-delta T cell activation|downregulation of gamma-delta T cell activation													biological_process											owl:Class	
GO:0061962	biolink:NamedThing	negative regulation of heme oxygenase activity	Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity.	got7fsn_ti							dph	2018-01-22T20:37:03Z						biological_process											owl:Class	
GO:0090555	biolink:NamedThing	phosphatidylethanolamine flippase activity	Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet)|ATPase-coupled phosphatidylethanolamine transporter activity|phosphatidylethanolamine-translocating ATPase activity|ATP-dependent phosphatidylethanolamine transporter activity				Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the exoplasmic to the cytosolic leaftlet of a membrane).		tb	2013-10-24T16:07:20Z				RHEA:66132		molecular_function											owl:Class	
GO:0030337	biolink:NamedThing	DNA polymerase processivity factor activity	An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.	got7fsn_ti	processivity clamp|sliding clamp													molecular_function											owl:Class	
GO:1901027	biolink:NamedThing	dextrin catabolic process	The chemical reactions and pathways resulting in the breakdown of dextrin.	got7fsn_ti	dextrin breakdown|dextrin catabolism|dextrin degradation						al	2012-06-19T03:12:19Z						biological_process											owl:Class	
GO:0015017	biolink:NamedThing	obsolete glypican	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	glypican				This term was made obsolete because it represents a gene product (was misspelled 'glycipan').					True				molecular_function											owl:Class	
GO:0019571	biolink:NamedThing	D-arabinose catabolic process	The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose.	got7fsn_ti	D-arabinose breakdown|D-arabinose catabolism|D-arabinose degradation													biological_process											owl:Class	
GO:0045567	biolink:NamedThing	obsolete negative regulation of TRAIL receptor 2 biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.	got7fsn_ti	downregulation of TRAIL receptor 2 biosynthetic process|negative regulation of TRAIL receptor 2 formation|negative regulation of TRAIL receptor 2 anabolism|down regulation of TRAIL receptor 2 biosynthetic process|inhibition of TRAIL receptor 2 biosynthetic process|negative regulation of TRAIL receptor 2 biosynthesis|down-regulation of TRAIL receptor 2 biosynthetic process|negative regulation of TRAIL receptor 2 synthesis	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0048288	biolink:NamedThing	nuclear membrane fusion involved in karyogamy	The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.	got7fsn_ti	nuclear membrane fusion during karyogamy													biological_process											owl:Class	
GO:0070393	biolink:NamedThing	teichoic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.	got7fsn_ti	teichoic acid catabolism|teichoic acid breakdown|teichoic acid degradation													biological_process											owl:Class	
GO:1902588	biolink:NamedThing	obsolete multi-organism plasmodesmata-mediated intercellular transport	OBSOLETE. A plasmodesmata-mediated intercellular transport which involves another organism.	got7fsn_ti	multi organism plasmodesmata-mediated intercellular transport				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-19T13:37:53Z		True				biological_process											owl:Class	
GO:1904198	biolink:NamedThing	negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization	Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.	got7fsn_ti	inhibition of regulation of vascular smooth muscle cell membrane depolarization|negative regulation of regulation of vascular smooth muscle cell membrane depolarization|down-regulation of regulation of vascular smooth muscle cell membrane depolarization|down regulation of regulation of vascular smooth muscle cell membrane depolarization|downregulation of regulation of vascular smooth muscle cell membrane depolarization						sl	2015-05-07T17:16:44Z						biological_process											owl:Class	
GO:1900096	biolink:NamedThing	negative regulation of dosage compensation by inactivation of X chromosome	Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.	got7fsn_ti	downregulation of X chromosome inactivation|down regulation of dosage compensation, by inactivation of X chromosome|down regulation of Barr body formation|inhibition of chromosome inactivation|downregulation of Barr body formation|negative regulation of Barr body formation|down regulation of chromosome inactivation|inhibition of Barr body formation|inhibition of X chromosome inactivation|down-regulation of chromosome inactivation|inhibition of dosage compensation, by inactivation of X chromosome|downregulation of chromosome inactivation|down regulation of X chromosome inactivation|down-regulation of Barr body formation|negative regulation of chromosome inactivation|down-regulation of X chromosome inactivation|down-regulation of dosage compensation, by inactivation of X chromosome|negative regulation of X chromosome inactivation|downregulation of dosage compensation, by inactivation of X chromosome						hjd	2012-02-14T07:29:49Z						biological_process											owl:Class	
GO:2001163	biolink:NamedThing	regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.	got7fsn_ti							se	2011-10-25T10:30:59Z						biological_process											owl:Class	
GO:0051080	biolink:NamedThing	meiosis II nuclear membrane disassembly	The controlled breakdown of the nuclear membranes during the second division of meiosis.	got7fsn_ti	meiosis II nuclear envelope breakdown|meiosis II nuclear envelope disassembly|meiosis II nuclear envelope degradation|meiosis II nuclear envelope catabolism													biological_process											owl:Class	
GO:0070249	biolink:NamedThing	positive regulation of natural killer cell apoptotic process	Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process.	got7fsn_ti	activation of natural killer cell apoptosis|stimulation of natural killer cell apoptosis|upregulation of natural killer cell apoptosis|up-regulation of natural killer cell apoptosis|positive regulation of natural killer cell apoptosis|up regulation of natural killer cell apoptosis|positive regulation of NK cell apoptosis													biological_process											owl:Class	
GO:1905461	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell apoptotic process	Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.	got7fsn_ti	up-regulation of vascular smooth muscle cell apoptosis|activation of vascular associated smooth muscle cell apoptosis|activation of vascular associated smooth muscle cell apoptotic process|activation of vascular smooth muscle cell apoptosis|upregulation of vascular smooth muscle cell apoptotic process|up regulation of vascular associated smooth muscle cell apoptotic process|positive regulation of VSMC apoptosis|up regulation of VSMC apoptosis|positive regulation of vascular associated smooth muscle cell apoptosis|up regulation of vascular associated smooth muscle cell apoptosis|upregulation of vascular associated smooth muscle cell apoptosis|up-regulation of vascular associated smooth muscle cell apoptotic process|up-regulation of vascular smooth muscle cell apoptotic process|upregulation of vascular smooth muscle cell apoptosis|up regulation of vascular smooth muscle cell apoptotic process|upregulation of VSMC apoptotic process|up regulation of VSMC apoptotic process|activation of VSMC apoptotic process|up regulation of vascular smooth muscle cell apoptosis|activation of vascular smooth muscle cell apoptotic process|upregulation of vascular associated smooth muscle cell apoptotic process|positive regulation of vascular smooth muscle cell apoptosis|up-regulation of VSMC apoptosis|positive regulation of vascular smooth muscle cell apoptotic process|up-regulation of vascular associated smooth muscle cell apoptosis|activation of VSMC apoptosis|positive regulation of VSMC apoptotic process|up-regulation of VSMC apoptotic process|upregulation of VSMC apoptosis						rph	2016-09-19T11:34:10Z						biological_process											owl:Class	
GO:0070299	biolink:NamedThing	positive regulation of phosphorelay signal transduction system	Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.	got7fsn_ti	upregulation of two-component signal transduction|up regulation of two-component signal transduction|activation of two-component signal transduction|stimulation of two-component signal transduction|positive regulation of histidyl-aspartyl phosphorelay|positive regulation of two-component signal transduction system (phosphorelay)|up-regulation of two-component signal transduction													biological_process											owl:Class	
GO:1901736	biolink:NamedThing	(R)-mevalonic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid.	got7fsn_ti	(R)-mevalonic acid degradation|(R)-mevalonate breakdown|(R)-mevalonate degradation|(R)-mevalonate catabolism|(R)-mevalonic acid breakdown|(R)-mevalonic acid catabolism						yaf	2013-01-11T11:25:55Z						biological_process											owl:Class	
GO:1900738	biolink:NamedThing	positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.	got7fsn_ti	up-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|up-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of PLC-activating GPCR signaling pathway|up-regulation of phospholipase C-activating dopamine receptor signaling pathway|upregulation of phospholipase C-activating G-protein coupled receptor signaling pathway|up regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up regulation of PLC-activating GPCR signaling pathway|upregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|positive regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|activation of phospholipase C-activating dopamine receptor signaling pathway|upregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of phospholipase C-activating G-protein coupled receptor signaling pathway|up-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of PLC-activating GPCR signaling pathway|activation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|positive regulation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|activation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|positive regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|upregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of phospholipase C-activating dopamine receptor signaling pathway|up regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of PLC-activating GPCR signaling pathway|up-regulation of PLC-activating GPCR signaling pathway|upregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|upregulation of phospholipase C-activating dopamine receptor signaling pathway						rl	2012-05-28T10:07:56Z						biological_process											owl:Class	
GO:1904263	biolink:NamedThing	positive regulation of TORC1 signaling	Any process that activates or increases the frequency, rate or extent of TORC1 signaling.	got7fsn_ti	activation of TORC1 signaling|upregulation of TORC1 signal transduction|up regulation of TORC1 signal transduction|up-regulation of TORC1 signaling|upregulation of TORC1 signaling|up regulation of TORC1 signaling|up-regulation of TORC1 signal transduction|positive regulation of TORC1 signal transduction|activation of TORC1 signal transduction						lb	2015-05-27T13:13:10Z						biological_process											owl:Class	
GO:1905442	biolink:NamedThing	cellular response to chondroitin 4'-sulfate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.	got7fsn_ti							cvs	2016-09-14T18:56:34Z						biological_process											owl:Class	
GO:0002692	biolink:NamedThing	negative regulation of cellular extravasation	Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation.	got7fsn_ti	inhibition of cellular extravasation|down-regulation of cellular extravasation|downregulation of cellular extravasation|down regulation of cellular extravasation													biological_process											owl:Class	
GO:0051343	biolink:NamedThing	positive regulation of cyclic-nucleotide phosphodiesterase activity	Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.	got7fsn_ti	upregulation of cyclic nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activator|cAMP phosphodiesterase activator|positive regulation of cyclic nucleotide phosphodiesterase activity|up regulation of cyclic nucleotide phosphodiesterase activity|stimulation of cyclic nucleotide phosphodiesterase activity|positive regulation of cAMP phosphodiesterase activity|phosphodiesterase activator|positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity|up-regulation of cyclic nucleotide phosphodiesterase activity|positive regulation of cGMP phosphodiesterase activity|3',5' cyclic nucleotide phosphodiesterase activator|positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity|activation of cyclic nucleotide phosphodiesterase activity													biological_process											owl:Class	
GO:0031394	biolink:NamedThing	positive regulation of prostaglandin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	got7fsn_ti	positive regulation of prostaglandin anabolism|up-regulation of prostaglandin biosynthetic process|activation of prostaglandin biosynthetic process|up regulation of prostaglandin biosynthetic process|positive regulation of prostaglandin formation|positive regulation of prostaglandin synthesis|positive regulation of prostaglandin biosynthesis|upregulation of prostaglandin biosynthetic process|stimulation of prostaglandin biosynthetic process													biological_process											owl:Class	
GO:1903495	biolink:NamedThing	cellular response to dehydroepiandrosterone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.	got7fsn_ti							mr	2014-09-25T17:01:26Z						biological_process											owl:Class	
GO:0004442	biolink:NamedThing	obsolete inositol-1,4,-bisphosphate 3-phosphatase	OBSOLETE. Catalysis of the reaction: D-myo-inositol 1,3-bisphosphate + H2O = D-myo-inositol 1-monophosphate + phosphate.	got7fsn_ti	inositol-1,4,-bisphosphate 3-phosphatase					GO:0004438				True				molecular_function											owl:Class	
GO:1902160	biolink:NamedThing	negative regulation of cyclic nucleotide-gated ion channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.	got7fsn_ti	downregulation of cyclic nucleotide-gated ion channel activity|downregulation of cyclic nucleotide gated ion channel activity|downregulation of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide-activated ion channel activity|down regulation of cyclic nucleotide gated ion channel activity|negative regulation of cyclic nucleotide gated ion channel activity|down regulation of cyclic nucleotide activated ion channel activity|negative regulation of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide activated ion channel activity|downregulation of cyclic nucleotide activated ion channel activity|inhibition of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide gated ion channel activity|inhibition of cyclic nucleotide gated ion channel activity|down-regulation of cyclic nucleotide-gated ion channel activity|down regulation of cyclic nucleotide-gated ion channel activity|inhibition of cyclic nucleotide-gated ion channel activity|negative regulation of cyclic nucleotide activated ion channel activity|inhibition of cyclic nucleotide activated ion channel activity|down regulation of cyclic nucleotide-activated ion channel activity						sl	2013-05-21T19:24:35Z						biological_process											owl:Class	
CHEBI:28599	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905400	biolink:NamedThing	negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.	got7fsn_ti	negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T cell apoptotic process|inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD4-positive, alpha-beta T cell apoptosis|negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|downregulation of activated CD4-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD4-positive, alpha-beta T cell apoptosis|down regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-cell apoptosis|downregulation of activated CD4-positive, alpha-beta T cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T cell apoptotic process|downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|inhibition of activated CD4-positive, alpha-beta T cell apoptosis|down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|negative regulation of activated CD4-positive, alpha-beta T cell apoptosis|inhibition of activated CD4-positive, alpha-beta T-cell apoptosis|inhibition of activated CD4-positive, alpha-beta T-cell apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-cell apoptosis|negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD4-positive, alpha-beta T-cell apoptosis|down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|negative regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|down-regulation of activated CD4-positive, alpha-beta T cell apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|downregulation of activated CD4-positive, alpha-beta T cell apoptotic process						pga	2016-08-25T09:09:53Z						biological_process											owl:Class	
GO:0005204	biolink:NamedThing	obsolete chondroitin sulfate proteoglycan	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	chondroitin sulfate proteoglycan|chondroitin sulphate proteoglycan				This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function.					True				molecular_function											owl:Class	
GO:1900395	biolink:NamedThing	negative regulation of kojic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process.	got7fsn_ti	negative regulation of C6H6O4 biosynthetic process|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down-regulation of kojic acid biosynthesis|down-regulation of C6H6O4 anabolism|negative regulation of kojic acid synthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|downregulation of C6H6O4 biosynthetic process|inhibition of kojic acid synthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|down regulation of kojic acid formation|downregulation of C6H6O4 formation|inhibition of C6H6O4 biosynthetic process|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|downregulation of kojic acid anabolism|downregulation of C6H6O4 anabolism|negative regulation of C6H6O4 biosynthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|inhibition of C6H6O4 anabolism|down-regulation of kojic acid anabolism|negative regulation of C6H6O4 synthesis|down-regulation of kojic acid formation|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|inhibition of C6H6O4 formation|negative regulation of C6H6O4 formation|negative regulation of C6H6O4 anabolism|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|downregulation of kojic acid synthesis|down-regulation of C6H6O4 synthesis|down regulation of kojic acid biosynthetic process|down regulation of C6H6O4 biosynthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|downregulation of kojic acid formation|down regulation of C6H6O4 synthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|inhibition of kojic acid formation|down-regulation of C6H6O4 biosynthetic process|downregulation of C6H6O4 synthesis|down regulation of C6H6O4 anabolism|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|inhibition of kojic acid biosynthesis|down-regulation of kojic acid biosynthetic process|down regulation of kojic acid anabolism|negative regulation of kojic acid formation|downregulation of kojic acid biosynthetic process|down-regulation of C6H6O4 biosynthesis|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|down-regulation of kojic acid synthesis|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|inhibition of C6H6O4 biosynthesis|inhibition of kojic acid biosynthetic process|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|inhibition of C6H6O4 synthesis|down regulation of C6H6O4 biosynthetic process|down regulation of C6H6O4 formation|down regulation of kojic acid synthesis|inhibition of kojic acid anabolism|down regulation of kojic acid biosynthesis|negative regulation of kojic acid anabolism|down-regulation of C6H6O4 formation|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|downregulation of C6H6O4 biosynthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|downregulation of kojic acid biosynthesis|negative regulation of kojic acid biosynthesis						di	2012-04-18T04:20:03Z						biological_process											owl:Class	
GO:1900159	biolink:NamedThing	positive regulation of bone mineralization involved in bone maturation	Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation.	got7fsn_ti	upregulation of bone mineralization involved in bone maturation|up-regulation of bone mineralization involved in bone maturation|activation of bone mineralization involved in bone maturation|up regulation of bone mineralization involved in bone maturation						vk	2012-03-07T08:55:16Z						biological_process											owl:Class	
GO:1904308	biolink:NamedThing	cellular response to desipramine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.	got7fsn_ti							sl	2015-06-10T17:00:37Z						biological_process											owl:Class	
GO:2000018	biolink:NamedThing	regulation of male gonad development	Any process that modulates the frequency, rate or extent of male gonad development.	got7fsn_ti	regulation of testicular development|regulation of testis development						jl	2010-07-15T03:29:05Z						biological_process											owl:Class	
GO:0016552	biolink:NamedThing	obsolete cotranscriptional insertion or deletion editing	OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during transcription.	got7fsn_ti	cotranscriptional insertion/deletion editing|cotranscriptional insertion or deletion editing				This term was made obsolete because it represents two separate processes (insertion and deletion).	GO:0070706|GO:0070705				True				biological_process											owl:Class	
GO:1900736	biolink:NamedThing	regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.	got7fsn_ti	regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|regulation of PLC-activating GPCR signaling pathway|regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|regulation of phospholipase C-activating dopamine receptor signaling pathway|regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger						rl	2012-05-28T10:07:27Z						biological_process											owl:Class	
GO:1902237	biolink:NamedThing	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.	got7fsn_ti	upregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up regulation of endoplasmic reticulum stress-induced apoptosis|up regulation of apoptosis triggered by ER stress|up regulation of apoptosis in response to ER stress|positive regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up-regulation of endoplasmic reticulum stress-induced apoptosis|positive regulation of ER stress-induced apoptosis|upregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up-regulation of apoptosis in response to ER stress|up regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|upregulation of endoplasmic reticulum stress-induced apoptosis|activation of ER stress-induced apoptosis|activation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|upregulation of apoptosis triggered by ER stress|up regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up regulation of ER stress-induced apoptosis|activation of endoplasmic reticulum stress-induced apoptosis|up-regulation of apoptosis triggered by ER stress|positive regulation of apoptosis triggered by ER stress|positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|upregulation of apoptosis in response to ER stress|activation of apoptosis triggered by ER stress|upregulation of ER stress-induced apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|activation of apoptosis in response to ER stress|positive regulation of apoptosis in response to ER stress|positive regulation of endoplasmic reticulum stress-induced apoptosis|up-regulation of ER stress-induced apoptosis|activation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress						rl	2013-06-18T15:19:49Z						biological_process											owl:Class	
GO:1900560	biolink:NamedThing	austinol biosynthetic process	The chemical reactions and pathways resulting in the formation of austinol.	got7fsn_ti	austinol anabolism|austinol formation|austinol synthesis|austinol biosynthesis						di	2012-05-15T06:27:30Z						biological_process											owl:Class	
GO:0051078	biolink:NamedThing	meiotic nuclear membrane disassembly	The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs.	got7fsn_ti	meiotic nuclear envelope catabolism|meiotic nuclear envelope degradation|meiotic nuclear envelope breakdown|meiotic nuclear envelope disassembly													biological_process											owl:Class	
GO:1903558	biolink:NamedThing	3-cyano-L-alanine metabolic process	The chemical reactions and pathways involving 3-cyano-L-alanine.	got7fsn_ti	3-cyano-L-alanine metabolism						kmv	2014-10-21T17:13:00Z						biological_process											owl:Class	
GO:0060287	biolink:NamedThing	epithelial cilium movement involved in determination of left/right asymmetry	The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves.	got7fsn_ti	Kuppfer's vesicle cilium movement involved in determination of left/right asymmetry|cilium movement involved in determinationof L/R asymmetry|nodal cilium movement involved in determination of left/right asymmetry													biological_process											owl:Class	
GO:1903240	biolink:NamedThing	obsolete negative regulation of positive regulation of the force of heart contraction by chemical signal	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal.	got7fsn_ti	downregulation of positive regulation of the force of heart muscle contraction by chemical signal|negative regulation of positive regulation of the force of heart contraction by chemical signal|downregulation of positive regulation of the force of heart contraction by chemical signal|down-regulation of positive regulation of the force of heart contraction by chemical signal|inhibition of positive regulation of the force of heart contraction by chemical signal|down regulation of positive regulation of the force of heart muscle contraction by chemical signal|negative regulation of positive regulation of the force of heart muscle contraction by chemical signal|down regulation of positive regulation of the force of heart contraction by chemical signal|inhibition of positive regulation of the force of heart muscle contraction by chemical signal|down-regulation of positive regulation of the force of heart muscle contraction by chemical signal				This term was obsoleted at the TermGenie Gatekeeper stage.		rl	2014-07-31T17:00:23Z		True				biological_process											owl:Class	
GO:0090355	biolink:NamedThing	positive regulation of auxin metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.	got7fsn_ti	positive regulation of auxin metabolism						tb	2010-06-29T01:51:18Z						biological_process											owl:Class	
GO:0001007	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase III transcription factor binding	OBSOLETE. Binding to an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	RNA polymerase III transcription factor binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2010-08-18T06:24:07Z		True				molecular_function											owl:Class	
GO:1901258	biolink:NamedThing	positive regulation of macrophage colony-stimulating factor production	Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production.	got7fsn_ti	up-regulation of macrophage colony-stimulating factor production|positive regulation of M-CSF production|upregulation of M-CSF production|up-regulation of M-CSF production|up regulation of M-CSF production|upregulation of macrophage colony-stimulating factor production|activation of macrophage colony-stimulating factor production|activation of M-CSF production|up regulation of macrophage colony-stimulating factor production						vk	2012-08-10T08:28:36Z						biological_process											owl:Class	
GO:1904246	biolink:NamedThing	negative regulation of polynucleotide adenylyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity.	got7fsn_ti	negative regulation of polyadenylate nucleotidyltransferase activity|downregulation of RNA formation factors, PF1|down-regulation of ATP:polynucleotide adenylyltransferase activity|down regulation of RNA adenylating enzyme activity|down-regulation of polyadenylate synthetase activity|down-regulation of poly-A polymerase activity|inhibition of poly(A) synthetase activity|down regulation of NTP polymerase activity|down regulation of ATP-polynucleotide adenylyltransferase activity|down-regulation of poly(A) hydrolase activity|down regulation of polyadenylic polymerase activity|inhibition of RNA formation factors, PF1|down-regulation of RNA formation factors, PF1|negative regulation of terminal riboadenylate transferase activity|negative regulation of polyadenylate synthetase activity|inhibition of polyadenylate polymerase activity|inhibition of AMP polynucleotidylexotransferase activity|inhibition of ATP-polynucleotide adenylyltransferase activity|downregulation of ATP-polynucleotide adenylyltransferase activity|downregulation of polyadenylic polymerase activity|down regulation of terminal riboadenylate transferase activity|downregulation of polynucleotide adenylyltransferase activity|negative regulation of poly(A) polymerase activity|negative regulation of polyadenylic acid polymerase activity|down-regulation of terminal riboadenylate transferase activity|down regulation of AMP polynucleotidylexotransferase activity|downregulation of polyadenylate nucleotidyltransferase activity|down-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|negative regulation of ATP:polynucleotide adenylyltransferase activity|down-regulation of RNA adenylating enzyme activity|downregulation of polyadenylate synthetase activity|down regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|inhibition of RNA adenylating enzyme activity|down-regulation of ATP:polynucleotidylexotransferase activity|inhibition of polyadenylic acid polymerase activity|inhibition of polynucleotide adenylyltransferase activity|downregulation of polyadenylate polymerase activity|downregulation of ATP:polynucleotidylexotransferase activity|down-regulation of ATP-polynucleotide adenylyltransferase activity|downregulation of poly(A) polymerase activity|down-regulation of polyadenylic acid polymerase activity|down regulation of ATP:polynucleotidylexotransferase activity|down-regulation of AMP polynucleotidylexotransferase activity|inhibition of poly-A polymerase activity|down-regulation of NTP polymerase activity|negative regulation of poly-A polymerase activity|negative regulation of poly(A) synthetase activity|down-regulation of polyadenylic polymerase activity|down regulation of ATP:polynucleotide adenylyltransferase activity|inhibition of polyadenylate synthetase activity|down-regulation of poly(A) polymerase activity|down regulation of poly(A) synthetase activity|downregulation of ATP:polynucleotide adenylyltransferase activity|inhibition of terminal riboadenylate transferase activity|inhibition of poly(A) hydrolase activity|down regulation of poly-A polymerase activity|downregulation of polyadenylic acid polymerase activity|negative regulation of ATP-polynucleotide adenylyltransferase activity|down-regulation of poly(A) synthetase activity|inhibition of NTP polymerase activity|negative regulation of NTP polymerase activity|negative regulation of RNA adenylating enzyme activity|downregulation of poly(A) synthetase activity|downregulation of poly-A polymerase activity|inhibition of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|negative regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down regulation of RNA formation factors, PF1|down regulation of polyadenylic acid polymerase activity|down-regulation of polynucleotide adenylyltransferase activity|down-regulation of polyadenylate polymerase activity|down regulation of poly(A) polymerase activity|down regulation of polyadenylate polymerase activity|negative regulation of RNA formation factors, PF1|downregulation of AMP polynucleotidylexotransferase activity|negative regulation of AMP polynucleotidylexotransferase activity|negative regulation of poly(A) hydrolase activity|inhibition of poly(A) polymerase activity|downregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down regulation of poly(A) hydrolase activity|down regulation of polyadenylate nucleotidyltransferase activity|down regulation of polynucleotide adenylyltransferase activity|negative regulation of polyadenylate polymerase activity|down-regulation of polyadenylate nucleotidyltransferase activity|inhibition of polyadenylic polymerase activity|downregulation of terminal riboadenylate transferase activity|down regulation of polyadenylate synthetase activity|inhibition of ATP:polynucleotide adenylyltransferase activity|negative regulation of polyadenylic polymerase activity|downregulation of RNA adenylating enzyme activity|negative regulation of ATP:polynucleotidylexotransferase activity|downregulation of NTP polymerase activity|inhibition of polyadenylate nucleotidyltransferase activity|downregulation of poly(A) hydrolase activity|inhibition of ATP:polynucleotidylexotransferase activity						kmv	2015-05-19T14:47:26Z						biological_process											owl:Class	
GO:0043526	biolink:NamedThing	obsolete neuroprotection	OBSOLETE. Any process that modulates the occurrence or rate of cell death by apoptosis in the nervous system. It may stop or prevent or reduce the rate of cell death by apoptosis and it is activated by stress to counteract death signals in central nervous systems. Different neuroprotective mechanisms may be activated to combat distinct types of cellular stress, ERK pathway is one of several neuroprotective mechanisms and it is a model system to study neuronal apoptosis, which may contribute to several neurodegenerative diseases and aging-related neuron loss.	got7fsn_ti	neuroprotection				This term was made obsolete because it refers to assays rather than processes. If neuron death by apoptosis is assessed, consider using GO:0043523 regulation of neuron apoptotic process. If neuron death is assessed but the cell death modality isn't defined, refer to GO:0070997 neuron death. Where non-neuronal cells are involved, and/or processes other than cell death are described, please use other terms for annotation.					True		Wikipedia:Neuroprotection		biological_process											owl:Class	
GO:2000798	biolink:NamedThing	negative regulation of amniotic stem cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation.	got7fsn_ti							yaf	2011-06-29T02:19:03Z						biological_process											owl:Class	
GO:2000661	biolink:NamedThing	positive regulation of interleukin-1-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway.	got7fsn_ti	positive regulation of IL-1-mediated signaling pathway|positive regulation of IL-1 beta-mediated signaling pathway|positive regulation of IL-1 alpha-mediated signaling pathway|positive regulation of interleukin-1-mediated signalling pathway|positive regulation of interleukin-1 beta-mediated signaling pathway|positive regulation of interleukin-1 alpha-mediated signaling pathway						dph	2011-05-03T07:13:40Z						biological_process											owl:Class	
GO:0034251	biolink:NamedThing	regulation of cellular amide catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.	got7fsn_ti	regulation of amide degradation|regulation of amide catabolism|regulation of amide breakdown													biological_process											owl:Class	
GO:0099105	biolink:NamedThing	ion channel modulating, G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel.	got7fsn_ti	ion channel modulating, G-protein coupled receptor signaling pathway													biological_process											owl:Class	
GO:1903347	biolink:NamedThing	negative regulation of bicellular tight junction assembly	Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly.	got7fsn_ti	down regulation of tight junction formation|inhibition of tight junction assembly|downregulation of tight junction formation|negative regulation of tight junction formation|down-regulation of tight junction assembly|down-regulation of tight junction formation|down regulation of tight junction assembly|inhibition of tight junction formation|downregulation of tight junction assembly						pr	2014-08-19T11:02:14Z						biological_process											owl:Class	
GO:1904224	biolink:NamedThing	negative regulation of glucuronosyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity.	got7fsn_ti	down-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down-regulation of 3-OH androgenic UDPGT activity|negative regulation of GT activity|downregulation of bilirubin uridine diphosphoglucuronyltransferase activity|downregulation of estriol UDPglucuronosyltransferase activity|inhibition of UDP-glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of PNP-UDPGT|downregulation of 3-OH androgenic UDPGT activity|down regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|inhibition of 3-OH androgenic UDPGT activity|downregulation of UDPGA-glucuronyltransferase activity|inhibition of p-phenylphenol glucuronyltransferase activity|down regulation of UDP glucuronyltransferase activity|down regulation of UDP glucuronate-estriol glucuronosyltransferase activity|inhibition of PNP-UDPGT|downregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|downregulation of uridine diphosphate glucuronyltransferase activity|down regulation of bilirubin UDPGT activity|negative regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronyltransferase activity|inhibition of bilirubin glucuronyltransferase activity|down-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of UDPGA transferase activity|downregulation of UDPGT activity|down regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down regulation of bilirubin UDP-glucuronosyltransferase activity|down regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|downregulation of uridine diphosphoglucuronosyltransferase activity|negative regulation of UDPGA-glucuronyltransferase activity|down regulation of 4-nitrophenol UDPGT activity|down-regulation of UDP glucuronyltransferase activity|inhibition of bilirubin monoglucuronide glucuronyltransferase activity|down-regulation of GT activity|negative regulation of p-nitrophenol UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|inhibition of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|negative regulation of UDPGT activity|downregulation of bilirubin UDP-glucuronosyltransferase activity|inhibition of estriol UDPglucuronosyltransferase activity|down-regulation of p-phenylphenol glucuronyltransferase activity|down-regulation of UDP-glucuronyltransferase activity|down regulation of UDP-glucuronyltransferase activity|inhibition of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|downregulation of bilirubin glucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|negative regulation of UDP-glucuronosyltransferase activity|negative regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down regulation of 1-naphthol glucuronyltransferase activity|downregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|negative regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|negative regulation of uridine diphosphoglucuronyltransferase activity|down regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of bilirubin UDPGT activity|inhibition of 4-nitrophenol UDPGT activity|inhibition of p-nitrophenol UDP-glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|downregulation of p-nitrophenol UDP-glucuronosyltransferase activity|down regulation of morphine glucuronyltransferase activity|negative regulation of UDPGA transferase activity|negative regulation of pnp-UDPGT activity|downregulation of estrone UDPglucuronosyltransferase activity|inhibition of p-nitrophenol UDP-glucuronosyltransferase activity|downregulation of 17-OH steroid UDPGT activity|inhibition of uridine diphosphate glucuronyltransferase activity|down regulation of p-nitrophenol UDP-glucuronosyltransferase activity|downregulation of UDP-glucuronosyltransferase activity|down regulation of pnp-UDPGT activity|downregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down-regulation of UDPGT activity|inhibition of UDP glucuronate-estradiol-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|inhibition of UDPGA transferase activity|down-regulation of bilirubin glucuronyltransferase activity|negative regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|negative regulation of uridine 5'-diphosphoglucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of p-nitrophenol UDP-glucuronyltransferase activity|down regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|downregulation of bilirubin monoglucuronide glucuronyltransferase activity|inhibition of 4-nitrophenol UDP-glucuronyltransferase activity|downregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|negative regulation of bilirubin monoglucuronide glucuronyltransferase activity|negative regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|down-regulation of UDP glucuronate-estriol glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|inhibition of uridine 5'-diphosphoglucuronyltransferase activity|downregulation of p-nitrophenol UDP-glucuronyltransferase activity|negative regulation of UDP glucuronic acid transferase activity|down-regulation of phenyl-UDP-glucuronosyltransferase activity|inhibition of UDP glucuronyltransferase activity|downregulation of 1-naphthol-UDP-glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|down-regulation of 17-OH steroid UDPGT activity|inhibition of UDPGT activity|down regulation of p-nitrophenylglucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|negative regulation of bilirubin uridine diphosphoglucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|downregulation of morphine glucuronyltransferase activity|downregulation of bilirubin UDPGT activity|negative regulation of UDP glucuronosyltransferase activity|down regulation of p-phenylphenol glucuronyltransferase activity|negative regulation of morphine glucuronyltransferase activity|inhibition of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down-regulation of uridine diphosphate glucuronyltransferase activity|down regulation of uridine diphosphate glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down regulation of PNP-UDPGT|down regulation of UDP-glucuronosyltransferase activity|down regulation of estriol UDPglucuronosyltransferase activity|downregulation of UDP glucuronic acid transferase activity|negative regulation of UDP glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|negative regulation of 1-naphthol-UDP-glucuronosyltransferase activity|inhibition of p-hydroxybiphenyl UDP glucuronyltransferase activity|negative regulation of p-phenylphenol glucuronyltransferase activity|down-regulation of p-nitrophenylglucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|down regulation of 4-nitrophenol UDP-glucuronyltransferase activity|down-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|downregulation of 4-nitrophenol UDP-glucuronyltransferase activity|inhibition of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down-regulation of morphine glucuronyltransferase activity|down-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of estrone UDPglucuronosyltransferase activity|downregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down regulation of ciramadol UDP-glucuronyltransferase activity|inhibition of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of 1-naphthol-UDP-glucuronosyltransferase activity|negative regulation of bilirubin UDP-glucuronosyltransferase activity|down-regulation of 1-naphthol-UDP-glucuronosyltransferase activity|negative regulation of UDP-glucuronyltransferase activity|inhibition of pnp-UDPGT activity|inhibition of p-nitrophenylglucuronosyltransferase activity|down-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|downregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|downregulation of p-nitrophenylglucuronosyltransferase activity|downregulation of p-phenylphenol glucuronyltransferase activity|downregulation of UDP glucuronate-estriol glucuronosyltransferase activity|inhibition of UDP glucuronic acid transferase activity|down-regulation of 4-nitrophenol UDPGT activity|inhibition of UDP-glucuronyltransferase activity|downregulation of GT activity|down-regulation of p-nitrophenol UDP-glucuronyltransferase activity|inhibition of UDP-glucuronate-bilirubin glucuronyltransferase activity|negative regulation of bilirubin glucuronyltransferase activity|downregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|inhibition of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of 1-naphthol glucuronyltransferase activity|inhibition of uridine diphosphoglucuronyltransferase activity|negative regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|downregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of 17-OH steroid UDPGT activity|down-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|downregulation of ciramadol UDP-glucuronyltransferase activity|down-regulation of pnp-UDPGT activity|down regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|negative regulation of PNP-UDPGT|negative regulation of phenyl-UDP-glucuronosyltransferase activity|inhibition of UDP glucuronate-estriol glucuronosyltransferase activity|inhibition of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of UDPGA transferase activity|inhibition of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|downregulation of pnp-UDPGT activity|down-regulation of estriol UDPglucuronosyltransferase activity|negative regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|downregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|negative regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of PNP-UDPGT|down-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|negative regulation of 3-OH androgenic UDPGT activity|down-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of bilirubin glucuronyltransferase activity|down regulation of 3-OH androgenic UDPGT activity|downregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down regulation of glucuronosyltransferase activity|negative regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of 17-OH steroid UDPGT activity|down-regulation of UDPGA-glucuronyltransferase activity|down-regulation of UDP glucuronic acid transferase activity|downregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|inhibition of morphine glucuronyltransferase activity|down-regulation of UDP glucuronosyltransferase activity|negative regulation of bilirubin UDPGT activity|negative regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|down regulation of UDPGA-glucuronyltransferase activity|negative regulation of p-nitrophenol UDP-glucuronyltransferase activity|down-regulation of glucuronosyltransferase activity|inhibition of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|down regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|negative regulation of 4-nitrophenol UDPGT activity|inhibition of ciramadol UDP-glucuronyltransferase activity|negative regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of phenyl-UDP-glucuronosyltransferase activity|downregulation of uridine 5'-diphosphoglucuronyltransferase activity|down regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of p-nitrophenol UDP-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronosyltransferase activity|down regulation of bilirubin monoglucuronide glucuronyltransferase activity|down-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of UDP glucuronyltransferase activity|down regulation of UDPGA transferase activity|negative regulation of 4-nitrophenol UDP-glucuronyltransferase activity|down regulation of bilirubin uridine diphosphoglucuronyltransferase activity|down regulation of estrone UDPglucuronosyltransferase activity|inhibition of glucuronosyltransferase activity|negative regulation of p-nitrophenylglucuronosyltransferase activity|inhibition of estrone UDPglucuronosyltransferase activity|negative regulation of estriol UDPglucuronosyltransferase activity|down-regulation of ciramadol UDP-glucuronyltransferase activity|down regulation of UDPGT activity|downregulation of 4-nitrophenol UDPGT activity|inhibition of UDP glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|downregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronyltransferase activity|down regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of UDP glucuronosyltransferase activity|negative regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|inhibition of bilirubin uridine diphosphoglucuronyltransferase activity|downregulation of UDP-glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronosyltransferase activity|negative regulation of UDP glucuronate-estriol glucuronosyltransferase activity|down-regulation of bilirubin uridine diphosphoglucuronyltransferase activity|down-regulation of estrone UDPglucuronosyltransferase activity|down-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of bilirubin UDP-glucuronosyltransferase activity|down-regulation of 1-naphthol glucuronyltransferase activity|inhibition of phenyl-UDP-glucuronosyltransferase activity|negative regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of UDP glucuronic acid transferase activity|down regulation of GT activity|down-regulation of 4-nitrophenol UDP-glucuronyltransferase activity|inhibition of GT activity|downregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of 1-naphthol-UDP-glucuronosyltransferase activity|inhibition of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down-regulation of bilirubin monoglucuronide glucuronyltransferase activity|downregulation of 1-naphthol glucuronyltransferase activity|inhibition of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|inhibition of bilirubin UDP-glucuronosyltransferase activity|negative regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|downregulation of UDP glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|down-regulation of UDP-glucuronosyltransferase activity|negative regulation of 17-OH steroid UDPGT activity|downregulation of glucuronosyltransferase activity|downregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|downregulation of phenyl-UDP-glucuronosyltransferase activity|inhibition of UDPGA-glucuronyltransferase activity|negative regulation of uridine diphosphate glucuronyltransferase activity|down regulation of uridine 5'-diphosphoglucuronyltransferase activity|down regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of ciramadol UDP-glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronyltransferase activity|down-regulation of uridine 5'-diphosphoglucuronyltransferase activity|inhibition of bilirubin UDPGT activity|inhibition of uridine diphosphoglucuronosyltransferase activity|inhibition of 1-naphthol glucuronyltransferase activity				i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species		rl	2015-05-15T08:44:26Z						biological_process											owl:Class	
GO:0070109	biolink:NamedThing	positive regulation of interleukin-27-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor.	got7fsn_ti	positive regulation of interleukin-27-mediated signalling pathway|positive regulation of IL-27-mediated signaling pathway|positive regulation of IL27RA/IL6ST signaling pathway													biological_process											owl:Class	
CHEBI:64618	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072333	biolink:NamedThing	obsolete anoikis by p53 class mediator	OBSOLETE. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, that results in the induction of anoikis.	got7fsn_ti	anoikis by p53 class mediator|signal transduction by p53 class mediator resulting in induction of anoikis|anoikis by signal transduction by p53 class mediator				This term was made obsolete because it is misleading, since anoikis occurs following detachment of cells from each other and/or from the culture surface; it is not p53 that induces such separation.		mah	2010-11-03T01:52:56Z		True				biological_process											owl:Class	
GO:0019796	biolink:NamedThing	obsolete nonprotein amino acid catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of any amino acid not found, or rarely found, in peptide linkage in proteins.	got7fsn_ti	nonprotein amino acid degradation|nonprotein amino acid breakdown|nonprotein amino acid catabolism|nonprotein amino acid catabolic process			GO:0009063	This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity.					True				biological_process											owl:Class	
GO:1900904	biolink:NamedThing	positive regulation of hexadecanal biosynthetic process	Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process.	got7fsn_ti	activation of palmitaldehyde biosynthesis|up regulation of palmitaldehyde biosynthetic process|up-regulation of hexadecanal synthesis|up-regulation of palmitaldehyde biosynthesis|positive regulation of hexadecanal anabolism|up regulation of hexadecanal anabolism|positive regulation of hexadecanal formation|activation of hexadecanal biosynthesis|positive regulation of hexadecanal biosynthesis|up regulation of hexadecanal synthesis|activation of palmitaldehyde biosynthetic process|upregulation of hexadecanal synthesis|upregulation of hexadecanal anabolism|activation of hexadecanal formation|up regulation of hexadecanal biosynthetic process|activation of hexadecanal biosynthetic process|up-regulation of hexadecanal biosynthetic process|activation of hexadecanal anabolism|upregulation of palmitaldehyde biosynthesis|upregulation of hexadecanal formation|up regulation of hexadecanal formation|up regulation of hexadecanal biosynthesis|up regulation of palmitaldehyde biosynthesis|up-regulation of hexadecanal biosynthesis|upregulation of hexadecanal biosynthesis|positive regulation of palmitaldehyde biosynthetic process|up-regulation of hexadecanal anabolism|upregulation of hexadecanal biosynthetic process|upregulation of palmitaldehyde biosynthetic process|positive regulation of hexadecanal synthesis|activation of hexadecanal synthesis|up-regulation of palmitaldehyde biosynthetic process|up-regulation of hexadecanal formation|positive regulation of palmitaldehyde biosynthesis						tt	2012-06-13T03:33:42Z						biological_process											owl:Class	
GO:0052118	biolink:NamedThing	obsolete positive energy taxis in host environment	OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive energy taxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0097015	biolink:NamedThing	obsolete bacterial-type flagellar cytoplasm	OBSOLETE. All of the contents of a bacterial-type flagellum, excluding the plasma membrane surrounding the flagellum.	got7fsn_ti	bacterial-type flagellum cytoplasm				The reason for obsoletion is that this term describes a cellular component that does not exist.		pr	2011-03-23T01:59:44Z		True				cellular_component											owl:Class	
CHEBI:38164	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097434	biolink:NamedThing	succinate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in).	got7fsn_ti	succinate:hydrogen symporter activity						pr	2012-11-26T18:19:42Z						molecular_function											owl:Class	
GO:1901158	biolink:NamedThing	neomycin biosynthetic process	The chemical reactions and pathways resulting in the formation of neomycin.	got7fsn_ti	neomycin synthesis|neomycin formation|neomycin anabolism|neomycin biosynthesis						yaf	2012-07-17T04:28:28Z						biological_process											owl:Class	
GO:0019831	biolink:NamedThing	obsolete chromate sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	chromate sensitivity/resistance			GO:0046687	This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0002861	biolink:NamedThing	regulation of inflammatory response to antigenic stimulus	Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0043405	biolink:NamedThing	regulation of MAP kinase activity	Any process that modulates the frequency, rate or extent of MAP kinase activity.	got7fsn_ti	regulation of mitogen activated protein kinase activity|Regulation of MAPK activity|regulation of mitogen-activated protein kinase activity													biological_process											owl:Class	
GO:0043003	biolink:NamedThing	positive regulation of Golgi to plasma membrane CFTR protein transport	Any process that activates or increases the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.	got7fsn_ti	up-regulation of Golgi to plasma membrane CFTR protein transport|stimulation of Golgi to plasma membrane CFTR protein transport|up regulation of Golgi to plasma membrane CFTR protein transport|activation of Golgi to plasma membrane CFTR protein transport|upregulation of Golgi to plasma membrane CFTR protein transport													biological_process											owl:Class	
GO:2000682	biolink:NamedThing	obsolete positive regulation of rubidium ion transport	OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transport.	got7fsn_ti	positive regulation of rubidium cation transport|positive regulation of Rb+ transport				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-10T10:54:37Z		True				biological_process											owl:Class	
GO:1902249	biolink:NamedThing	IMP binding	Binding to IMP, inosine monophosphate.	got7fsn_ti							mah	2013-06-20T16:20:35Z						molecular_function											owl:Class	
GO:0006547	biolink:NamedThing	histidine metabolic process	The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	got7fsn_ti	histidine metabolism											Wikipedia:Histidine		biological_process											owl:Class	
GO:1900031	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling	OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|regulation of global transcription from Pol II promoter of calcium signalling|regulation of transcription from RNA polymerase II promoter, global of calcium ion signaling|global transcription regulation from Pol II promoter of calcium signaling|regulation of transcription from Pol II promoter of calcium-mediated signalling|regulation of global transcription from Pol II promoter of calcium signaling|regulation of global transcription from Pol II promoter of calcium ion signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling|regulation of transcription from RNA polymerase II promoter, global of calcium signalling|regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global of calcium signaling|regulation of transcription from Pol II promoter of calcium signalling|regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signalling|regulation of transcription from Pol II promoter of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter of calcium signaling|regulation of transcription from Pol II promoter of calcium signaling|global transcription regulation from Pol II promoter of calcium ion signaling|regulation of global transcription from Pol II promoter of calcium-mediated signalling|global transcription regulation from Pol II promoter of calcium-mediated signalling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter of calcium ion signaling|regulation of transcription from Pol II promoter of calcium ion signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling|regulation of transcription from RNA polymerase II promoter of calcium signalling|regulation of global transcription from Pol II promoter of calcium-mediated signaling|global transcription regulation from Pol II promoter of calcium signalling|global transcription regulation from Pol II promoter of calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling					GO:0019722|GO:0006357	krc	2012-01-13T04:09:19Z		True				biological_process											owl:Class	
GO:0000299	biolink:NamedThing	obsolete integral to membrane of membrane fraction	OBSOLETE. Integral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; require detergents, such as Triton X-100, to be released from membranes.	got7fsn_ti	integral to membrane of membrane fraction				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0016021				True				cellular_component											owl:Class	
GO:0030803	biolink:NamedThing	obsolete negative regulation of cyclic nucleotide biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.	got7fsn_ti	negative regulation of cyclic nucleotide formation|down regulation of cyclic nucleotide biosynthetic process|negative regulation of cyclic nucleotide biosynthesis|negative regulation of cyclic nucleotide synthesis|down-regulation of cyclic nucleotide biosynthetic process|negative regulation of cyclic nucleotide anabolism|inhibition of cyclic nucleotide biosynthetic process|downregulation of cyclic nucleotide biosynthetic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:1903159	biolink:NamedThing	obsolete malate transmembrane transporter activity involved in malate import into cell	OBSOLETE. Any malate transmembrane transporter activity that is involved in malate import into cell.	got7fsn_ti	dicarboxylate (succinate/fumarate/malate) antiporter activity involved in malate import into cell|malate transmembrane transporter activity involved in malate import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:27Z		True				molecular_function											owl:Class	
GO:1901224	biolink:NamedThing	positive regulation of NIK/NF-kappaB signaling	Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.	got7fsn_ti	up-regulation of non-canonical NF-KB signaling|positive regulation of p52-dependent NF-kappaB signaling|activation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|release of NF-kappaB sequestered in cytoplasm|up-regulation of NIK/NF-kappaB cascade|positive regulation of NIK/NF-kappaB cascade|release of cytoplasmic sequestered NF-kappaB|up-regulation of p52-dependent NF-kappaB signaling|upregulation of NIK/NF-kappaB cascade|positive regulation of NF-kappaB import into nucleus|up regulation of noncanonical NF-kappaB signaling|up-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|upregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|upregulation of noncanonical NF-kappaB signaling|activation of p52-dependent NF-kappaB signaling|upregulation of non-canonical NF-KB signaling|up regulation of p52-dependent NF-kappaB signaling|activation of noncanonical NF-kappaB signaling|positive regulation of noncanonical NF-kappaB signaling|positive regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|positive regulation of non-canonical NF-KB signaling|up-regulation of noncanonical NF-kappaB signaling|activation of non-canonical NF-KB signaling|up regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|upregulation of p52-dependent NF-kappaB signaling|up regulation of NIK/NF-kappaB cascade|up regulation of non-canonical NF-KB signaling|activation of NIK/NF-kappaB cascade|negative regulation of cytoplasmic NF-kappaB storage						hjd	2012-08-06T20:27:47Z			GO:0008588|GO:0042346			biological_process											owl:Class	
GO:1902445	biolink:NamedThing	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death.	got7fsn_ti	regulation of transport across mitochondrial membrane involved in programmed necrotic cell death						dph	2013-10-11T13:11:20Z						biological_process											owl:Class	
GO:0048325	biolink:NamedThing	negative regulation of axial mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination.	got7fsn_ti	downregulation of axial mesodermal cell fate determination|inhibition of axial mesodermal cell fate determination|down-regulation of axial mesodermal cell fate determination|down regulation of axial mesodermal cell fate determination													biological_process											owl:Class	
GO:1904233	biolink:NamedThing	negative regulation of aconitate hydratase activity	Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity.	got7fsn_ti	inhibition of citrate(isocitrate) hydro-lyase activity|down-regulation of cis-aconitase activity|down-regulation of aconitase activity|down regulation of aconitate hydratase activity|downregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|downregulation of aconitate hydratase activity|down regulation of citrate(isocitrate) hydro-lyase activity|down-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|inhibition of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|downregulation of aconitase activity|down regulation of cis-aconitase activity|negative regulation of aconitase activity|down regulation of aconitase activity|down-regulation of citrate(isocitrate) hydro-lyase activity|negative regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|negative regulation of citrate(isocitrate) hydro-lyase activity|negative regulation of cis-aconitase activity|inhibition of cis-aconitase activity|downregulation of cis-aconitase activity|downregulation of citrate(isocitrate) hydro-lyase activity|inhibition of aconitase activity|down regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down-regulation of aconitate hydratase activity|inhibition of aconitate hydratase activity						rl	2015-05-15T09:55:23Z						biological_process											owl:Class	
GO:0120266	biolink:NamedThing	positive regulation of chromosome attachment to the nuclear envelope	Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope.	got7fsn_ti	stimulation of chromosome attachment to the nuclear envelope|up-regulation of chromosome attachment to the nuclear envelope|activation of chromosome attachment to the nuclear envelope|upregulation of chromosome attachment to the nuclear envelope|up regulation of chromosome attachment to the nuclear envelope	https://github.com/geneontology/go-ontology/issues/20020					krc	2020-09-29T20:30:45Z						biological_process											owl:Class	
GO:1902092	biolink:NamedThing	positive regulation of fumagillin biosynthetic process	Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process.	got7fsn_ti	up-regulation of fumagillin anabolism|up-regulation of fumagillin formation|up regulation of fumagillin biosynthetic process|up regulation of fumagillin biosynthesis|activation of fumagillin anabolism|upregulation of fumagillin synthesis|upregulation of fumagillin anabolism|activation of fumagillin formation|positive regulation of fumagillin biosynthesis|up-regulation of fumagillin synthesis|positive regulation of fumagillin formation|activation of fumagillin synthesis|upregulation of fumagillin biosynthetic process|activation of fumagillin biosynthetic process|up regulation of fumagillin synthesis|up regulation of fumagillin anabolism|upregulation of fumagillin biosynthesis|positive regulation of fumagillin synthesis|activation of fumagillin biosynthesis|positive regulation of fumagillin anabolism|up regulation of fumagillin formation|up-regulation of fumagillin biosynthetic process|up-regulation of fumagillin biosynthesis|upregulation of fumagillin formation						di	2013-04-27T03:45:09Z						biological_process											owl:Class	
GO:0044607	biolink:NamedThing	obsolete disruption by symbiont of host endothelial cells	OBSOLETE. Any process in which an organism has a negative effect on the functioning of the host's endothelial cells.	got7fsn_ti					This term was obsoleted because the cell type should be captured as an annotation extension.		jl	2012-05-30T02:24:50Z		True				biological_process											owl:Class	
GO:1905854	biolink:NamedThing	negative regulation of heparan sulfate binding	Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding.	got7fsn_ti	downregulation of heparan sulfate binding|inhibition of heparan sulfate binding|down regulation of heparan sulfate binding|down-regulation of heparan sulfate binding						bc	2017-01-23T13:25:38Z						biological_process											owl:Class	
GO:0019454	biolink:NamedThing	L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4).	got7fsn_ti	L-cysteine degradation via cystine, using glutathione-cystine transhydrogenase|L-cysteine breakdown via cystine, using glutathione-cystine transhydrogenase													biological_process											owl:Class	
GO:0004287	biolink:NamedThing	obsolete prolyl oligopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of Pro-Xaa > Ala-Xaa in oligopeptides.	got7fsn_ti	endoprolylpeptidase activity|post-proline endopeptidase activity|prolyl endopeptidase activity|proline-specific endopeptidase activity|post-proline cleaving enzyme activity|proline endopeptidase activity|prolyl oligopeptidase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905273	biolink:NamedThing	positive regulation of proton-transporting ATP synthase activity, rotational mechanism	Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.	got7fsn_ti	up-regulation of hydrogen ion transporting two-sector ATPase activity|up-regulation of hydrogen ion translocating F-type ATPase activity|up-regulation of H+-transporting ATP synthase activity|up regulation of proton-transporting ATP synthase activity, rotational mechanism|upregulation of proton-transporting ATP synthase activity, rotational mechanism|up-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|upregulation of hydrogen ion transporting two-sector ATPase activity|up-regulation of proton-transporting ATP synthase activity, rotational mechanism|activation of H+-transporting ATP synthase activity|up regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|upregulation of hydrogen ion translocating F-type ATPase activity|positive regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|upregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|activation of proton-transporting ATP synthase activity, rotational mechanism|upregulation of H+-transporting ATP synthase activity|up regulation of hydrogen ion translocating F-type ATPase activity|positive regulation of H+-transporting ATP synthase activity|positive regulation of hydrogen ion transporting two-sector ATPase activity|up regulation of hydrogen ion transporting two-sector ATPase activity|activation of hydrogen ion translocating F-type ATPase activity|positive regulation of hydrogen ion translocating F-type ATPase activity|activation of hydrogen ion transporting two-sector ATPase activity|activation of hydrogen ion transporting ATP synthase activity, rotational mechanism|up regulation of H+-transporting ATP synthase activity						als	2016-06-16T12:10:05Z						biological_process											owl:Class	
CHEBI:26441	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033345	biolink:NamedThing	asparagine catabolic process via L-aspartate	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.	got7fsn_ti												MetaCyc:ASPARAGINE-DEG1-PWY		biological_process											owl:Class	
GO:0033497	biolink:NamedThing	sinapate biosynthetic process	The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.	got7fsn_ti	sinapate synthesis|sinapate biosynthesis|sinapate anabolism|sinapate formation											MetaCyc:PWY-5168		biological_process											owl:Class	
GO:1905358	biolink:NamedThing	positive regulation of snRNA pseudouridine synthesis	Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis.	got7fsn_ti	up-regulation of snRNA pseudouridine synthesis|up regulation of snRNA pseudouridine synthesis|upregulation of snRNA pseudouridine synthesis|activation of snRNA pseudouridine synthesis						se	2016-08-09T19:12:42Z						biological_process											owl:Class	
GO:0015072	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase, class I, catalyst activity	OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.	got7fsn_ti	phosphatidylinositol 3-kinase, class I, catalyst activity				This term was made obsolete because it represents a class of gene products.	GO:0035005|GO:0016303|GO:0046934				True				molecular_function											owl:Class	
GO:1902287	biolink:NamedThing	semaphorin-plexin signaling pathway involved in axon guidance	Any semaphorin-plexin signaling pathway that is involved in axon guidance.	got7fsn_ti	semaphorin-plexin signaling pathway involved in axon pathfinding|semaphorin-plexin signalling pathway involved in axon pathfinding|semaphorin-plexin signalling pathway involved in axon guidance|semaphorin-plexin signalling pathway involved in axon growth cone guidance|semaphorin-plexin signalling pathway involved in axon chemotaxis|semaphorin-plexin signaling pathway involved in axon chemotaxis|semaphorin-plexin signaling pathway involved in axon growth cone guidance						pr	2013-07-08T16:07:03Z						biological_process											owl:Class	
GO:1902651	biolink:NamedThing	positive regulation of histone H2A-H2B dimer displacement	Any process that activates or increases the frequency, rate or extent of histone H2A-H2B dimer displacement.	got7fsn_ti	upregulation of histone H2A-H2B dimer displacement|up regulation of histone H2A-H2B dimer displacement|activation of histone H2A-H2B dimer displacement|up-regulation of histone H2A-H2B dimer displacement						di	2014-01-21T18:19:23Z						biological_process											owl:Class	
GO:1905512	biolink:NamedThing	regulation of short-term synaptic potentiation	Any process that modulates the frequency, rate or extent of short-term synaptic potentiation.	got7fsn_ti	regulation of synaptic facilitation						hjd	2016-09-28T17:40:15Z						biological_process											owl:Class	
GO:0051344	biolink:NamedThing	negative regulation of cyclic-nucleotide phosphodiesterase activity	Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.	got7fsn_ti	cAMP phosphodiesterase inhibitor|3',5' cyclic nucleotide phosphodiesterase inhibitor|negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity|negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity|negative regulation of cGMP phosphodiesterase activity|down-regulation of cyclic nucleotide phosphodiesterase activity|down regulation of cyclic nucleotide phosphodiesterase activity|negative regulation of cyclic nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase inhibitor|negative regulation of cAMP phosphodiesterase activity|phosphodiesterase inhibitor|inhibition of cyclic nucleotide phosphodiesterase activity|downregulation of cyclic nucleotide phosphodiesterase activity													biological_process											owl:Class	
GO:0080158	biolink:NamedThing	obsolete chloroplast ribulose bisphosphate carboxylase complex biogenesis	OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a chloroplast ribulose bisphosphate carboxylase (RubisCO) complex. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15173			The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		dhl	2010-09-01T04:05:55Z		True				biological_process											owl:Class	
GO:2000780	biolink:NamedThing	negative regulation of double-strand break repair	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair.	got7fsn_ti							bf	2011-06-23T09:28:08Z						biological_process											owl:Class	
GO:1902396	biolink:NamedThing	protein localization to bicellular tight junction	A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.	got7fsn_ti	protein localisation in tight junction|protein localization in tight junction|protein localisation to tight junction						tb	2013-09-11T21:43:13Z						biological_process											owl:Class	
GO:1904775	biolink:NamedThing	positive regulation of ubiquinone biosynthetic process	Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process.	got7fsn_ti	up-regulation of ubiquinone biosynthesis|positive regulation of coenzyme Q9 biosynthesis|upregulation of coenzyme Q8 biosynthesis|activation of coenzyme Q8 biosynthesis|up regulation of coenzyme Q9 biosynthetic process|upregulation of coenzyme Q6 biosynthesis|up regulation of ubiquinone anabolism|up regulation of coenzyme Q biosynthesis|activation of coenzyme Q biosynthetic process|activation of coenzyme Q8 biosynthetic process|up-regulation of coenzyme Q biosynthesis|upregulation of ubiquinone formation|activation of coenzyme Q10 biosynthesis|up regulation of coenzyme Q9 biosynthesis|activation of ubiquinone biosynthesis|activation of coenzyme Q biosynthesis|up-regulation of coenzyme Q10 biosynthetic process|positive regulation of ubiquinone anabolism|positive regulation of ubiquinone biosynthesis|up-regulation of ubiquinone synthesis|up regulation of coenzyme Q6 biosynthesis|upregulation of coenzyme Q9 biosynthesis|up regulation of coenzyme Q10 biosynthesis|upregulation of ubiquinone synthesis|positive regulation of coenzyme Q6 biosynthetic process|upregulation of coenzyme Q biosynthetic process|up-regulation of ubiquinone anabolism|activation of ubiquinone synthesis|activation of coenzyme Q10 biosynthetic process|activation of coenzyme Q9 biosynthesis|upregulation of coenzyme Q6 biosynthetic process|positive regulation of coenzyme Q biosynthetic process|up-regulation of coenzyme Q8 biosynthesis|up-regulation of coenzyme Q6 biosynthesis|activation of ubiquinone formation|positive regulation of ubiquinone formation|upregulation of coenzyme Q9 biosynthetic process|up regulation of ubiquinone biosynthetic process|activation of coenzyme Q6 biosynthesis|activation of coenzyme Q9 biosynthetic process|up-regulation of coenzyme Q9 biosynthesis|up regulation of coenzyme Q10 biosynthetic process|up-regulation of ubiquinone formation|positive regulation of coenzyme Q10 biosynthetic process|positive regulation of coenzyme Q8 biosynthetic process|up regulation of ubiquinone synthesis|upregulation of ubiquinone anabolism|upregulation of coenzyme Q10 biosynthetic process|up-regulation of ubiquinone biosynthetic process|positive regulation of coenzyme Q6 biosynthesis|activation of ubiquinone biosynthetic process|upregulation of ubiquinone biosynthetic process|up-regulation of coenzyme Q6 biosynthetic process|positive regulation of coenzyme Q9 biosynthetic process|up-regulation of coenzyme Q8 biosynthetic process|up-regulation of coenzyme Q10 biosynthesis|positive regulation of coenzyme Q10 biosynthesis|upregulation of coenzyme Q10 biosynthesis|upregulation of ubiquinone biosynthesis|upregulation of coenzyme Q8 biosynthetic process|positive regulation of coenzyme Q8 biosynthesis|positive regulation of ubiquinone synthesis|activation of coenzyme Q6 biosynthetic process|up regulation of ubiquinone biosynthesis|up regulation of ubiquinone formation|up-regulation of coenzyme Q9 biosynthetic process|up regulation of coenzyme Q8 biosynthetic process|activation of ubiquinone anabolism|up regulation of coenzyme Q6 biosynthetic process|up-regulation of coenzyme Q biosynthetic process|up regulation of coenzyme Q biosynthetic process|positive regulation of coenzyme Q biosynthesis|up regulation of coenzyme Q8 biosynthesis|upregulation of coenzyme Q biosynthesis						sl	2015-10-28T21:21:26Z						biological_process											owl:Class	
GO:0045233	biolink:NamedThing	obsolete natural killer cell receptor activity	OBSOLETE. A receptor found on the surface of natural killer cells which binds Class I MHC antigens and is required for activation of NK activity. It belongs to the Ly49i family.	got7fsn_ti	Ly49i|NK cell receptor activity|natural killer cell receptor activity				This term was made obsolete because the receptor is defined based on its cellular expression pattern, and the definition is inaccurate: receptors on natural killer cells can either activate or inhibit natural killer (NK) cell-mediated cytotoxicity.	GO:0002769|GO:0004888|GO:0030101				True				molecular_function											owl:Class	
GO:1903168	biolink:NamedThing	positive regulation of pyrroline-5-carboxylate reductase activity	Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.	got7fsn_ti	upregulation of L-proline oxidase activity|activation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|up regulation of L-proline oxidase activity|activation of pyrroline-5-carboxylate reductase activity|up-regulation of L-proline oxidase activity|positive regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|up regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|upregulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|activation of L-proline oxidase activity|positive regulation of 1-pyrroline-5-carboxylate reductase activity|upregulation of pyrroline-5-carboxylate reductase activity|up regulation of 1-pyrroline-5-carboxylate reductase activity|positive regulation of P5CR activity|up regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up-regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|activation of L-proline:NAD(P)+ 5-oxidoreductase activity|up regulation of pyrroline-5-carboxylate reductase activity|up-regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|upregulation of L-proline-NAD(P)+ 5-oxidoreductase activity|activation of L-proline-NAD(P)+ 5-oxidoreductase activity|up regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|up-regulation of pyrroline-5-carboxylate reductase activity|upregulation of 1-pyrroline-5-carboxylate reductase activity|positive regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|positive regulation of L-proline oxidase activity|up regulation of P5CR activity|upregulation of P5CR activity|up-regulation of 1-pyrroline-5-carboxylate reductase activity|activation of 1-pyrroline-5-carboxylate reductase activity|activation of P5CR activity|positive regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up-regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up-regulation of P5CR activity|upregulation of L-proline:NAD(P)+ 5-oxidoreductase activity						bf	2014-07-09T19:51:25Z						biological_process											owl:Class	
GO:0006025	biolink:NamedThing	galactosaminoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.	got7fsn_ti	galactosaminoglycan synthesis|galactosaminoglycan formation|galactosaminoglycan anabolism|galactosaminoglycan biosynthesis													biological_process											owl:Class	
GO:0140146	biolink:NamedThing	calcium ion import into vacuole	The directed movement of calcium cations into the vacuole across the vacuolar membrane.	got7fsn_ti							pg	2017-12-13T15:15:29Z						biological_process											owl:Class	
GO:0071936	biolink:NamedThing	coreceptor activity involved in Wnt signaling pathway	In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway.	got7fsn_ti	coreceptor activity involved in Wnt receptor signaling pathway|coreceptor activity involved in Wnt-activated signaling pathway|Wnt co-receptor activity|coreceptor activity involved in Wnt receptor signalling pathway						mah	2010-09-30T03:54:34Z						molecular_function											owl:Class	
GO:1904350	biolink:NamedThing	regulation of protein catabolic process in the vacuole	Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole.	got7fsn_ti	regulation of vacuolar protein breakdown|regulation of vacuolar protein catabolism|regulation of vacuolar protein degradation|regulation of vacuolar protein catabolic process						rl	2015-06-12T09:10:36Z						biological_process											owl:Class	
GO:0071579	biolink:NamedThing	regulation of zinc ion transport	Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							mah	2010-01-28T03:02:15Z						biological_process											owl:Class	
GO:0046914	biolink:NamedThing	transition metal ion binding	Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	got7fsn_ti														molecular_function											owl:Class	
GO:1903208	biolink:NamedThing	negative regulation of hydrogen peroxide-induced neuron death	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced neuron death.	got7fsn_ti	negative regulation of neuron death in response to H2O2|down-regulation of neuron death in response to hydrogen peroxide|protection against hydrogen peroxide-induced neuron death|protection against H2O2-induced neuron death|down-regulation of neuron death in response to H2O2|negative regulation of neuronal cell death in response to hydrogen peroxide|downregulation of neuron death in response to hydrogen peroxide|downregulation of neuronal cell death in response to hydrogen peroxide|down regulation of hydrogen peroxide-induced neuron death|neuroprotection against hydrogen peroxide|downregulation of hydrogen peroxide-induced neuron death|down-regulation of hydrogen peroxide-induced neuron death|down-regulation of neuronal cell death in response to hydrogen peroxide|down regulation of neuron death in response to hydrogen peroxide|negative regulation of neuron death in response to hydrogen peroxide|down regulation of neuron death in response to H2O2|downregulation of neuron death in response to H2O2|inhibition of hydrogen peroxide-induced neuron death|inhibition of neuronal cell death in response to hydrogen peroxide|inhibition of neuron death in response to H2O2|neuroprotection against H2O2-induced cell death|inhibition of neuron death in response to hydrogen peroxide|down regulation of neuronal cell death in response to hydrogen peroxide						bf	2014-07-21T16:27:11Z						biological_process											owl:Class	
GO:0046850	biolink:NamedThing	regulation of bone remodeling	Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.	got7fsn_ti														biological_process											owl:Class	
GO:0045717	biolink:NamedThing	negative regulation of fatty acid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.	got7fsn_ti	negative regulation of fatty acid synthesis|down regulation of fatty acid biosynthetic process|downregulation of fatty acid biosynthetic process|negative regulation of fatty acid anabolism|negative regulation of fatty acid biosynthesis|inhibition of fatty acid biosynthetic process|down-regulation of fatty acid biosynthetic process|negative regulation of fatty acid formation													biological_process											owl:Class	
GO:1900634	biolink:NamedThing	pentadecane biosynthetic process	The chemical reactions and pathways resulting in the formation of pentadecane.	got7fsn_ti	pentadecane formation|pentadecane synthesis|pentadecane biosynthesis|pentadecane anabolism						tt	2012-05-21T06:51:57Z						biological_process											owl:Class	
GO:0000736	biolink:NamedThing	double-strand break repair via single-strand annealing, removal of nonhomologous ends	During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.	got7fsn_ti														biological_process											owl:Class	
GO:1903118	biolink:NamedThing	urate homeostasis	Any process involved in the maintenance of an internal steady state of urate within an organism or cell.	got7fsn_ti							dph	2014-06-13T14:54:51Z						biological_process											owl:Class	
GO:0052449	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042511	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031437	biolink:NamedThing	regulation of mRNA cleavage	Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.	got7fsn_ti														biological_process											owl:Class	
GO:1902326	biolink:NamedThing	positive regulation of chlorophyll biosynthetic process	Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process.	got7fsn_ti	activation of chlorophyll anabolism|upregulation of chlorophyll synthesis|activation of chlorophyll formation|activation of chlorophyll biosynthesis|positive regulation of chlorophyll biosynthesis|positive regulation of chlorophyll formation|up regulation of chlorophyll synthesis|up regulation of chlorophyll biosynthetic process|up regulation of chlorophyll formation|up regulation of chlorophyll biosynthesis|up-regulation of chlorophyll anabolism|upregulation of chlorophyll anabolism|upregulation of chlorophyll biosynthetic process|up regulation of chlorophyll anabolism|up-regulation of chlorophyll biosynthesis|activation of chlorophyll synthesis|activation of chlorophyll biosynthetic process|up-regulation of chlorophyll synthesis|up-regulation of chlorophyll biosynthetic process|upregulation of chlorophyll formation|up-regulation of chlorophyll formation|positive regulation of chlorophyll synthesis|positive regulation of chlorophyll anabolism|upregulation of chlorophyll biosynthesis						tb	2013-07-24T22:47:37Z						biological_process											owl:Class	
GO:1900366	biolink:NamedThing	negative regulation of defense response to insect	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect.	got7fsn_ti	down regulation of physiological defense response to insect|susceptibility to insect|down regulation of defense response to insect|downregulation of defense response to insect|down-regulation of defense response to insect|inhibition of defense response to insect|downregulation of physiological defense response to insect|inhibition of physiological defense response to insect|down-regulation of physiological defense response to insect|negative regulation of physiological defense response to insect						dhl	2012-04-12T04:44:00Z						biological_process											owl:Class	
GO:0009172	biolink:NamedThing	purine deoxyribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside monophosphate breakdown|purine deoxyribonucleoside monophosphate catabolism|purine deoxyribonucleoside monophosphate degradation													biological_process											owl:Class	
GO:1902173	biolink:NamedThing	negative regulation of keratinocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.	got7fsn_ti	down-regulation of keratinocyte apoptotic process|down regulation of keratinocyte apoptotic process|negative regulation of keratinocyte apoptosis|downregulation of keratinocyte apoptosis|inhibition of keratinocyte apoptotic process|downregulation of keratinocyte apoptotic process|down-regulation of keratinocyte apoptosis|inhibition of keratinocyte apoptosis|down regulation of keratinocyte apoptosis						rl	2013-05-29T14:36:15Z						biological_process											owl:Class	
GO:0005638	biolink:NamedThing	lamin filament	Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C.	got7fsn_ti	type V intermediate filament													cellular_component											owl:Class	
GO:1902281	biolink:NamedThing	negative regulation of RNA helicase activity	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity.	got7fsn_ti	negative regulation of ATP-dependent RNA helicase activity|down-regulation of ATP-dependent RNA helicase activity|downregulation of ATP-dependent RNA helicase activity|down regulation of ATP-dependent RNA helicase activity|inhibition of ATP-dependent RNA helicase activity						rb	2013-07-03T18:05:25Z						biological_process											owl:Class	
GO:1903500	biolink:NamedThing	negative regulation of mitotic actomyosin contractile ring assembly	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly.	got7fsn_ti	down regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|inhibition of actomyosin contractile ring assembly involved in cytokinesis after mitosis|negative regulation of mitotic cytokinesis, actomyosin contractile ring assembly|down regulation of mitotic actomyosin contractile ring assembly|down regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|negative regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|down regulation of contractile ring assembly involved in mitotic cytokinesis|down-regulation of contractile ring assembly involved in mitotic cytokinesis|inhibition of contractile ring assembly involved in mitotic cytokinesis|downregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|down-regulation of mitotic actomyosin contractile ring assembly|down-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|downregulation of mitotic actomyosin contractile ring assembly|negative regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|down-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|downregulation of contractile ring assembly involved in mitotic cytokinesis|inhibition of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|inhibition of mitotic actomyosin contractile ring assembly|negative regulation of contractile ring assembly involved in mitotic cytokinesis|downregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis						pr	2014-09-30T10:13:59Z						biological_process											owl:Class	
GO:1903657	biolink:NamedThing	negative regulation of type IV pilus biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis.	got7fsn_ti	down regulation of type IV fimbriae biogenesis|inhibition of TFP biogenesis|down regulation of type IV pilus biosynthesis|downregulation of type IV fimbrium assembly|down-regulation of type 4 pilus biogenesis|down-regulation of type IV fimbrial biogenesis|down-regulation of type IV fimbrium biogenesis|down-regulation of type IV pilus biogenesis|down-regulation of type IV fimbria biogenesis|downregulation of type IV fimbrium biogenesis|down-regulation of type IV fimbrial assembly|down regulation of type IV fimbrial assembly|inhibition of type IV fimbrium assembly|down-regulation of type IV pilus biosynthesis|downregulation of type IV pilus biogenesis|downregulation of type IV fimbrial biogenesis|down-regulation of type IV fimbria assembly|downregulation of type IV fimbria biogenesis|negative regulation of TFP biogenesis|negative regulation of type IV fimbriae biogenesis|downregulation of type IV fimbrial assembly|negative regulation of type IV fimbria biogenesis|down-regulation of type IV fimbriae assembly|downregulation of type 4 pilus biogenesis|down regulation of type IV fimbrial biogenesis|down regulation of type IV fimbriae assembly|negative regulation of type IV fimbrium assembly|inhibition of type IV pilus biogenesis|negative regulation of type IV fimbrial biogenesis|down regulation of type IV fimbrium biogenesis|inhibition of type IV pilus biosynthesis|down-regulation of TFP biogenesis|inhibition of type IV fimbrium biogenesis|downregulation of type IV pilus biosynthesis|inhibition of type IV fimbrial assembly|down-regulation of type IV fimbriae biogenesis|down-regulation of type IV fimbrium assembly|down regulation of type IV pilus biogenesis|inhibition of type IV fimbria biogenesis|inhibition of type IV fimbria assembly|negative regulation of type IV fimbriae assembly|inhibition of type IV fimbriae biogenesis|downregulation of TFP biogenesis|negative regulation of type IV fimbria assembly|down regulation of type 4 pilus biogenesis|downregulation of type IV fimbria assembly|down regulation of TFP biogenesis|down regulation of type IV fimbrium assembly|negative regulation of type IV pilus biosynthesis|downregulation of type IV fimbriae biogenesis|down regulation of type IV fimbria biogenesis|inhibition of type 4 pilus biogenesis|inhibition of type IV fimbriae assembly|down regulation of type IV fimbria assembly|inhibition of type IV fimbrial biogenesis|downregulation of type IV fimbriae assembly|negative regulation of type 4 pilus biogenesis|negative regulation of type IV fimbrium biogenesis|negative regulation of type IV fimbrial assembly						jl	2014-11-25T12:03:24Z						biological_process											owl:Class	
GO:0001938	biolink:NamedThing	positive regulation of endothelial cell proliferation	Any process that activates or increases the rate or extent of endothelial cell proliferation.	got7fsn_ti	stimulation of endothelial cell proliferation|upregulation of endothelial cell proliferation|up-regulation of endothelial cell proliferation|activation of endothelial cell proliferation|up regulation of endothelial cell proliferation													biological_process											owl:Class	
GO:0004600	biolink:NamedThing	obsolete cyclophilin	OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity.	got7fsn_ti	cyclophilin				This term was made obsolete because it does not represent a molecular function.	GO:0016018|GO:0003755				True				molecular_function											owl:Class	
GO:0035958	biolink:NamedThing	obsolete regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of the glyoxylate cycle by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of glyoxylate bypass by regulation of transcription from Pol II promoter|regulation of glyoxylate cycle by regulation of transcription from Pol II promoter|regulation of glyoxylate bypass by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0019482	biolink:NamedThing	beta-alanine metabolic process	The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.	got7fsn_ti	beta-alanine metabolism											Wikipedia:Beta-alanine		biological_process											owl:Class	
GO:0006592	biolink:NamedThing	ornithine biosynthetic process	The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.	got7fsn_ti	ornithine synthesis|ornithine biosynthesis|ornithine anabolism|ornithine formation													biological_process											owl:Class	
GO:1902879	biolink:NamedThing	obsolete negative regulation of BMP signaling pathway involved in spinal cord association neuron specification	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.	got7fsn_ti	inhibition of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down regulation of BMP signalling pathway involved in spinal cord association neuron specification|inhibition of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|down regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|inhibition of BMP signalling pathway involved in spinal cord association neuron specification|inhibition of BMP signaling pathway involved in spinal cord association neuron specification|down regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|negative regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down-regulation of BMP signalling pathway involved in spinal cord association neuron specification|down regulation of BMP signaling pathway involved in spinal cord association neuron specification|down-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|downregulation of BMP signaling pathway involved in spinal cord association neuron specification|downregulation of BMP signalling pathway involved in spinal cord association neuron specification|negative regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|downregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|negative regulation of BMP signalling pathway involved in spinal cord association neuron specification|down-regulation of BMP signaling pathway involved in spinal cord association neuron specification|downregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification				The reason for obsoletion is that this term represents a GO-CAM model.		mr	2014-04-03T15:25:38Z		True				biological_process											owl:Class	
GO:1902347	biolink:NamedThing	response to strigolactone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.	got7fsn_ti	response to strigolactone analog GR24						dhl	2013-08-08T18:44:57Z						biological_process											owl:Class	
GO:1901865	biolink:NamedThing	capsorubin catabolic process	The chemical reactions and pathways resulting in the breakdown of capsorubin.	got7fsn_ti	capsorubin degradation|capsorubin catabolism|capsorubin breakdown						yaf	2013-02-04T10:50:17Z						biological_process											owl:Class	
GO:1903170	biolink:NamedThing	negative regulation of calcium ion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.	got7fsn_ti	down regulation of calcium ion transmembrane transport|downregulation of calcium ion membrane transport|inhibition of calcium ion membrane transport|downregulation of transmembrane calcium transport|inhibition of calcium ion transmembrane transport|down-regulation of transmembrane calcium transport|down regulation of calcium ion membrane transport|down-regulation of calcium ion membrane transport|inhibition of transmembrane calcium transport|downregulation of calcium ion transmembrane transport|negative regulation of transmembrane calcium transport|down-regulation of calcium ion transmembrane transport|negative regulation of calcium ion membrane transport|down regulation of transmembrane calcium transport				human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol		rl	2014-07-11T17:09:32Z						biological_process											owl:Class	
GO:1902138	biolink:NamedThing	(-)-secoisolariciresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol.	got7fsn_ti	(-)-secoisolariciresinol anabolism|(-)-secoisolariciresinol synthesis|(-)-secoisolariciresinol formation|(-)-secoisolariciresinol biosynthesis						ms	2013-05-21T08:50:29Z						biological_process											owl:Class	
GO:0016353	biolink:NamedThing	obsolete carbamate susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	carbamate susceptibility/resistance			GO:0046681	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:2001185	biolink:NamedThing	regulation of CD8-positive, alpha-beta T cell activation	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.	got7fsn_ti							yaf	2011-11-03T01:16:51Z						biological_process											owl:Class	
GO:1904024	biolink:NamedThing	negative regulation of glucose catabolic process to lactate via pyruvate	Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.	got7fsn_ti	down-regulation of homofermentation|inhibition of glucose catabolic process to lactate via pyruvate|inhibition of homofermentative pathway|downregulation of homolactic fermentation|down regulation of glucose catabolic process to lactate via pyruvate|inhibition of homolactate fermentation|down regulation of homolactate fermentation|inhibition of homofermentative lactate fermentation|downregulation of glucose catabolic process to lactate via pyruvate|inhibition of homofermentation|down regulation of homolactic fermentation|downregulation of glucose fermentation to lactate via pyruvate|down regulation of homofermentation|negative regulation of homofermentative lactate fermentation|down-regulation of glucose fermentation to lactate via pyruvate|downregulation of homofermentative pathway|down-regulation of glucose catabolic process to lactate via pyruvate|downregulation of homofermentation|down regulation of homofermentative pathway|down regulation of homofermentative lactate fermentation|negative regulation of homolactate fermentation|down-regulation of homofermentative pathway|negative regulation of homofermentative pathway|negative regulation of glucose fermentation to lactate via pyruvate|negative regulation of homolactic fermentation|inhibition of homolactic fermentation|downregulation of homolactate fermentation|down regulation of glucose fermentation to lactate via pyruvate|downregulation of homofermentative lactate fermentation|down-regulation of homolactic fermentation|inhibition of glucose fermentation to lactate via pyruvate|down-regulation of homofermentative lactate fermentation|negative regulation of homofermentation|down-regulation of homolactate fermentation						dph	2015-03-11T16:57:38Z						biological_process											owl:Class	
GO:0051404	biolink:NamedThing	obsolete clostripain activity	OBSOLETE. Catalysis of the cleavage of Arg-Xaa bonds.	got7fsn_ti	alpha-clostridipain|Clostridium histolyticum proteinase B|clostripain activity|clostridiopeptidase B activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0051814	biolink:NamedThing	obsolete movement in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism or its progeny spreads from one location to another within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	movement within other organism during symbiotic interaction|movement in other organism during symbiotic interaction				This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:1903614	biolink:NamedThing	negative regulation of protein tyrosine phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity.	got7fsn_ti	downregulation of protein-tyrosine-phosphatase activity|down-regulation of protein-tyrosine-phosphate phosphohydrolase activity|down regulation of phosphotyrosine histone phosphatase activity|downregulation of tyrosylprotein phosphatase activity|inhibition of protein tyrosine phosphatase activity|down regulation of PPT-phosphatase activity|down regulation of PTP-phosphatase activity|inhibition of phosphotyrosine histone phosphatase activity|inhibition of PTP-phosphatase activity|inhibition of protein-tyrosine-phosphate phosphohydrolase activity|inhibition of [phosphotyrosine]protein phosphatase activity|inhibition of phosphotyrosylprotein phosphatase activity|inhibition of phosphotyrosine protein phosphatase activity|down-regulation of tyrosylprotein phosphatase activity|downregulation of PTPase activity|down-regulation of [phosphotyrosine]protein phosphatase activity|down regulation of [phosphotyrosine]protein phosphatase activity|down-regulation of phosphotyrosine histone phosphatase activity|downregulation of PTP-phosphatase activity|negative regulation of phosphotyrosine protein phosphatase activity|down-regulation of protein-tyrosine-phosphatase activity|inhibition of phosphotyrosine phosphatase activity|negative regulation of protein-tyrosine-phosphate phosphohydrolase activity|down-regulation of PTP-phosphatase activity|negative regulation of phosphoprotein phosphatase (phosphotyrosine) activity|negative regulation of phosphotyrosine histone phosphatase activity|down-regulation of PTPase activity|down regulation of phosphotyrosine phosphatase activity|down regulation of protein-tyrosine-phosphatase activity|down-regulation of protein phosphotyrosine phosphatase activity|downregulation of phosphoprotein phosphatase (phosphotyrosine) activity|down regulation of phosphoprotein phosphatase (phosphotyrosine) activity|negative regulation of PTP-phosphatase activity|down-regulation of PPT-phosphatase activity|downregulation of protein tyrosine phosphatase activity|negative regulation of phosphotyrosylprotein phosphatase activity|downregulation of protein phosphotyrosine phosphatase activity|negative regulation of protein-tyrosine-phosphatase activity|inhibition of tyrosine O-phosphate phosphatase activity|negative regulation of [phosphotyrosine]protein phosphatase activity|down-regulation of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of protein-tyrosine-phosphatase activity|negative regulation of phosphotyrosine phosphatase activity|down regulation of PTPase activity|downregulation of phosphotyrosine protein phosphatase activity|downregulation of [phosphotyrosine]protein phosphatase activity|inhibition of tyrosylprotein phosphatase activity|downregulation of tyrosine O-phosphate phosphatase activity|down-regulation of phosphotyrosine phosphatase activity|downregulation of phosphotyrosine phosphatase activity|down-regulation of phosphotyrosylprotein phosphatase activity|downregulation of PPT-phosphatase activity|downregulation of phosphotyrosine histone phosphatase activity|negative regulation of tyrosine O-phosphate phosphatase activity|negative regulation of tyrosylprotein phosphatase activity|down-regulation of tyrosine O-phosphate phosphatase activity|down regulation of phosphotyrosine protein phosphatase activity|downregulation of phosphotyrosylprotein phosphatase activity|down regulation of tyrosylprotein phosphatase activity|down-regulation of protein tyrosine phosphatase activity|inhibition of protein phosphotyrosine phosphatase activity|down regulation of protein-tyrosine-phosphate phosphohydrolase activity|negative regulation of PPT-phosphatase activity|down regulation of protein tyrosine phosphatase activity|down regulation of protein phosphotyrosine phosphatase activity|inhibition of PPT-phosphatase activity|downregulation of protein-tyrosine-phosphate phosphohydrolase activity|negative regulation of PTPase activity|inhibition of PTPase activity|negative regulation of protein phosphotyrosine phosphatase activity|down regulation of tyrosine O-phosphate phosphatase activity|inhibition of phosphoprotein phosphatase (phosphotyrosine) activity|down-regulation of phosphotyrosine protein phosphatase activity|down regulation of phosphotyrosylprotein phosphatase activity						sl	2014-11-18T01:11:46Z						biological_process											owl:Class	
GO:1905197	biolink:NamedThing	endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling	Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid.	got7fsn_ti	endocannabinoid signalling pathway involved in retrograde trans-synaptic signaling by endocannabinoid						dos	2016-05-12T14:29:38Z						biological_process											owl:Class	
GO:0033396	biolink:NamedThing	beta-alanine biosynthetic process via 3-ureidopropionate	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.	got7fsn_ti	beta-alanine formation via 3-ureidopropionate|beta-alanine synthesis via 3-ureidopropionate|beta-alanine anabolism via 3-ureidopropionate											MetaCyc:PWY-3982		biological_process											owl:Class	
GO:1902447	biolink:NamedThing	negative regulation of shade avoidance	Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance.	got7fsn_ti	down regulation of shade avoidance|downregulation of shade avoidance|down-regulation of shade avoidance|inhibition of shade avoidance						dhl	2013-10-15T21:04:51Z						biological_process											owl:Class	
GO:0016218	biolink:NamedThing	obsolete polyketide synthase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	polyketide synthase activity			GO:0030639	This term was made obsolete because the activity it describes does not exist, and the gene product with the name 'polyketide synthase' has multiple functional domains, so using the name to describe a single function would be misleading.	GO:0034081				True				molecular_function											owl:Class	
GO:1901236	biolink:NamedThing	4-(trimethylammonio)butanoate transmembrane transporter activity	Enables the transfer of 4-(trimethylammonio)butanoate from one side of a membrane to the other.	got7fsn_ti							jl	2012-08-07T14:46:52Z				RHEA:32835		molecular_function											owl:Class	
GO:1904808	biolink:NamedThing	positive regulation of protein oxidation	Any process that activates or increases the frequency, rate or extent of protein oxidation.	got7fsn_ti	up regulation of protein amino acid oxidation|positive regulation of protein amino acid oxidation|upregulation of protein amino acid oxidation|up-regulation of protein amino acid oxidation|upregulation of protein oxidation|up-regulation of protein oxidation|up regulation of protein oxidation|activation of protein amino acid oxidation|activation of protein oxidation						mec	2015-11-10T14:06:15Z						biological_process											owl:Class	
GO:1990366	biolink:NamedThing	obsolete response to organic acid	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic acid.	got7fsn_ti	response to organic acid				This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:21:26Z		True				biological_process											owl:Class	
GO:0051792	biolink:NamedThing	medium-chain fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of any fatty acid with a chain length of between C6 and C12.	got7fsn_ti	medium-chain fatty acid synthesis|medium-chain fatty acid anabolism|medium chain fatty acid biosynthetic process|medium-chain fatty acid biosynthesis|medium chain fatty acid biosynthesis|medium-chain fatty acid formation													biological_process											owl:Class	
GO:1904603	biolink:NamedThing	regulation of advanced glycation end-product receptor activity	Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity.	got7fsn_ti	regulation of RAGE activity|regulation of AGE receptor activity						krc	2015-08-26T16:24:49Z						biological_process											owl:Class	
GO:1900129	biolink:NamedThing	positive regulation of G-protein activated inward rectifier potassium channel activity	Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.	got7fsn_ti	up regulation of G protein activated inward rectifier potassium channel activity|up-regulation of G-protein enhanced inward rectifier potassium channel activity|up-regulation of G protein enhanced inward rectifier potassium channel activity|positive regulation of G protein activated inward rectifier potassium channel activity|positive regulation of G-protein enhanced inward rectifier potassium channel activity|upregulation of G-protein-activated inward rectifier potassium channel activity|up regulation of G-protein activated inward rectifier potassium channel activity|activation of G protein enhanced inward rectifier potassium channel activity|activation of G-protein-activated inward rectifier potassium channel activity|upregulation of G protein activated inward rectifier potassium channel activity|up regulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G-protein-enhanced inward rectifier potassium channel activity|activation of G protein activated inward rectifier potassium channel activity|activation of G-protein-enhanced inward rectifier potassium channel activity|activation of G-protein enhanced inward rectifier potassium channel activity|up-regulation of G-protein-enhanced inward rectifier potassium channel activity|up-regulation of G-protein-activated inward rectifier potassium channel activity|up-regulation of G-protein activated inward rectifier potassium channel activity|up regulation of G-protein enhanced inward rectifier potassium channel activity|positive regulation of G protein enhanced inward rectifier potassium channel activity|positive regulation of G-protein-activated inward rectifier potassium channel activity|upregulation of G-protein activated inward rectifier potassium channel activity|upregulation of G-protein enhanced inward rectifier potassium channel activity|up regulation of G-protein-activated inward rectifier potassium channel activity|upregulation of G-protein-enhanced inward rectifier potassium channel activity|activation of G-protein activated inward rectifier potassium channel activity|up-regulation of G protein activated inward rectifier potassium channel activity|positive regulation of G-protein-enhanced inward rectifier potassium channel activity|upregulation of G protein enhanced inward rectifier potassium channel activity						bf	2012-02-23T03:12:58Z						biological_process											owl:Class	
GO:0050760	biolink:NamedThing	negative regulation of thymidylate synthase biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.	got7fsn_ti	negative regulation of thymidylate synthase biosynthesis|negative regulation of thymidylate synthase formation|down-regulation of thymidylate synthase biosynthetic process|negative regulation of thymidylate synthase anabolism|downregulation of thymidylate synthase biosynthetic process|negative regulation of thymidylate synthase synthesis|down regulation of thymidylate synthase biosynthetic process|inhibition of thymidylate synthase biosynthetic process													biological_process											owl:Class	
GO:1904864	biolink:NamedThing	negative regulation of beta-catenin-TCF complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly.	got7fsn_ti	down regulation of beta-catenin-TCF complex formation|down-regulation of beta-catenin-TCF complex formation|down-regulation of beta-catenin/T-cell factor complex assembly|downregulation of beta-catenin/LEF complex formation|down-regulation of beta-catenin/LEF complex assembly|down-regulation of beta-catenin/LEF complex formation|negative regulation of beta-catenin-TCF complex formation|inhibition of beta-catenin/lymphoid enhancer binding factor complex assembly|down regulation of beta-catenin/LEF complex formation|down regulation of beta-catenin/T-cell factor complex formation|negative regulation of beta-catenin/lymphoid enhancer binding factor complex formation|inhibition of beta-catenin-TCF complex formation|down regulation of beta-catenin/T-cell factor complex assembly|down-regulation of beta-catenin/lymphoid enhancer binding factor complex formation|down-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|downregulation of beta-catenin-TCF complex formation|down regulation of beta-catenin-TCF complex assembly|inhibition of beta-catenin/T-cell factor complex formation|down regulation of beta-catenin/lymphoid enhancer binding factor complex formation|negative regulation of beta-catenin/T-cell factor complex assembly|down-regulation of beta-catenin-TCF complex assembly|inhibition of beta-catenin/LEF complex formation|negative regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|down-regulation of beta-catenin/T-cell factor complex formation|inhibition of beta-catenin/LEF complex assembly|downregulation of beta-catenin/T-cell factor complex assembly|downregulation of beta-catenin/lymphoid enhancer binding factor complex formation|negative regulation of beta-catenin/T-cell factor complex formation|down regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|downregulation of beta-catenin/lymphoid enhancer binding factor complex assembly|inhibition of beta-catenin/lymphoid enhancer binding factor complex formation|inhibition of beta-catenin-TCF complex assembly|downregulation of beta-catenin/LEF complex assembly|downregulation of beta-catenin-TCF complex assembly|inhibition of beta-catenin/T-cell factor complex assembly|down regulation of beta-catenin/LEF complex assembly|negative regulation of beta-catenin/LEF complex assembly|downregulation of beta-catenin/T-cell factor complex formation|negative regulation of beta-catenin/LEF complex formation						bf	2015-12-17T13:50:46Z						biological_process											owl:Class	
GO:0051849	biolink:NamedThing	obsolete active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation	OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation pathway|active immune evasion via regulation of symbiont antigen processing or presentation|active immune evasion via modulation of symbiont antigen processing and presentation|active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation|active immune evasion via modulation of symbiont antigen processing/presentation				This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
GO:1902806	biolink:NamedThing	regulation of cell cycle G1/S phase transition	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.	got7fsn_ti							jl	2014-03-26T16:36:14Z						biological_process											owl:Class	
GO:0046072	biolink:NamedThing	dTDP metabolic process	The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate.	got7fsn_ti	dTDP metabolism													biological_process											owl:Class	
GO:0001617	biolink:NamedThing	obsolete growth hormone secretagogue-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	growth hormone secretagogue-like receptor activity				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True				molecular_function											owl:Class	
GO:1904810	biolink:NamedThing	negative regulation of dense core granule transport	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport.	got7fsn_ti	inhibition of dense core vesicle transport|downregulation of dense core granule transport|down-regulation of dense core granule transport|down regulation of dense core granule transport|down regulation of dense core vesicle transport|downregulation of dense core vesicle transport|down-regulation of dense core vesicle transport|inhibition of dense core granule transport|negative regulation of dense core vesicle transport				cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).		es	2015-11-11T10:40:18Z						biological_process											owl:Class	
GO:2000627	biolink:NamedThing	positive regulation of miRNA catabolic process	Any process that activates or increases the frequency, rate or extent of miRNA catabolic process.	got7fsn_ti	positive regulation of microRNA catabolic process						dph	2011-04-18T03:46:42Z						biological_process											owl:Class	
GO:1905957	biolink:NamedThing	regulation of cellular response to alcohol	Any process that modulates the frequency, rate or extent of cellular response to alcohol.	got7fsn_ti							hbye	2017-02-22T12:03:00Z						biological_process											owl:Class	
GO:1905502	biolink:NamedThing	acetyl-CoA binding	Binding to acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component.	got7fsn_ti	acetyl-coenzyme A binding						bc	2016-09-27T16:33:44Z						molecular_function											owl:Class	
GO:0046297	biolink:NamedThing	obsolete 2,4-dichlorobenzoate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).	got7fsn_ti	2,4-dichlorobenzoate formation|2,4-dichlorobenzoate synthesis|2,4-dichlorobenzoate biosynthesis|2,4-dichlorobenzoate anabolism|2,4-dichlorobenzoate biosynthetic process			GO:0018898	This term was made obsolete because 2,4-dichlorobenzoate is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1905425	biolink:NamedThing	negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.	got7fsn_ti	down-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt-mediated midbrain DA neuron differentiation|negative regulation of midbrain dopaminergic neuron differentiation by negative regulation of Wnt signaling|down-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|down-regulation of Wg signalling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|inhibition of Wg signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signalling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signaling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wingless signalling pathway involved in mDA neuron differentiation|down regulation of frizzled signaling pathway involved in mDA neuron differentiation|negative regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signalling pathway involved in mDA neuron differentiation|inhibition of Wnt receptor signalling pathway involved in mDA neuron differentiation|inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt-mediated midbrain DA neuron differentiation|negative regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|downregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in mDA neuron differentiation|down regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of frizzled signalling pathway involved in midbrain DA neurogenesis|down-regulation of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|downregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signaling pathway involved in mDA neuron differentiation|inhibition of frizzled signaling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|negative regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|inhibition of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signaling pathway involved in mDA neuron differentiation|inhibition of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signaling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signaling pathway involved in mDA neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down regulation of frizzled signalling pathway involved in mDA neuron differentiation|inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|inhibition of frizzled signalling pathway involved in mDA neuron differentiation|downregulation of Wg signaling pathway involved in mDA neuron differentiation|negative regulation of frizzled signaling pathway involved in mDA neuron differentiation|down regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signalling pathway involved in midbrain DA neurogenesis|downregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signalling pathway involved in mDA neuron differentiation|negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt signaling pathway involved in midbrain DA neurogenesis|down regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signalling pathway involved in mDA neuron differentiation|down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt signaling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signaling pathway involved in midbrain DA neurogenesis|inhibition of Wg signalling pathway involved in mDA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt-mediated midbrain DA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt signaling pathway involved in mDA neuron differentiation|negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in mDA neuron differentiation|downregulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of frizzled signalling pathway involved in mDA neuron differentiation|negative regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wg signalling pathway involved in midbrain DA neurogenesis|downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signalling pathway involved in mDA neuron differentiation|downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|downregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wg signaling pathway involved in midbrain DA neurogenesis|down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt signaling pathway involved in mDA neuron differentiation|downregulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt-mediated midbrain DA neuron differentiation|down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|downregulation of frizzled signalling pathway involved in mDA neuron differentiation|downregulation of Wnt-mediated midbrain DA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down regulation of Wg signaling pathway involved in mDA neuron differentiation|inhibition of Wingless signaling pathway involved in midbrain DA neurogenesis|down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signalling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of frizzled signalling pathway involved in mDA neuron differentiation|down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|negative regulation of Wg signaling pathway involved in mDA neuron differentiation|inhibition of frizzled signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signaling pathway involved in mDA neuron differentiation|negative regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signaling pathway involved in mDA neuron differentiation|down regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signalling pathway involved in mDA neuron differentiation|negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt-activated signaling pathway involved in mDA neuron differentiation|negative regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wg signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wingless signaling pathway involved in mDA neuron differentiation|negative regulation of Wingless signalling pathway involved in mDA neuron differentiation|down regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wingless signalling pathway involved in mDA neuron differentiation|down-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production						bf	2016-09-07T10:03:44Z						biological_process											owl:Class	
GO:0090371	biolink:NamedThing	regulation of glycerol transport	Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2010-07-12T11:30:22Z						biological_process											owl:Class	
GO:0080180	biolink:NamedThing	2-methylguanosine metabolic process	The chemical reactions and pathways involving 2-methylguanosine.	got7fsn_ti							dhl	2011-04-28T04:41:01Z						biological_process											owl:Class	
GO:1905815	biolink:NamedThing	regulation of dorsal/ventral axon guidance	Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance.	got7fsn_ti	regulation of dorsal/ventral axon pathfinding|regulation of dorsoventral axon guidance|regulation of dorsal-ventral axon guidance						hbye	2017-01-12T13:38:44Z						biological_process											owl:Class	
GO:1905126	biolink:NamedThing	regulation of axo-dendritic protein transport	Any process that modulates the frequency, rate or extent of axo-dendritic protein transport.	got7fsn_ti	regulation of axonal protein transport						sl	2016-04-11T20:38:31Z						biological_process											owl:Class	
GO:0090731	biolink:NamedThing	cellular response to very-low-density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus.	got7fsn_ti	cellular response to VLDL particle stimulus						tb	2017-01-31T17:10:08Z						biological_process											owl:Class	
CHEBI:37606	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000744	biolink:NamedThing	positive regulation of anterior head development	Any process that activates or increases the frequency, rate or extent of anterior head development.	got7fsn_ti							yaf	2011-06-14T09:44:17Z						biological_process											owl:Class	
GO:0015840	biolink:NamedThing	urea transport	The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.	got7fsn_ti														biological_process											owl:Class	
GO:1990480	biolink:NamedThing	obsolete geranyl diphosphate synthase	OBSOLETE. Catalyzes the condensation of dimethylallyl diphosphate and isopentenyl diphosphate to geranyl diphosphate, the key precursor of monoterpene biosynthesis.	got7fsn_ti				GO:0004161	This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-09-10T01:14:17Z		True				molecular_function											owl:Class	
GO:1900687	biolink:NamedThing	negative regulation of gerfelin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process.	got7fsn_ti	down-regulation of gerfelin synthesis|down regulation of gerfelin synthesis|inhibition of gerfelin formation|down-regulation of gerfelin formation|down-regulation of gerfelin biosynthesis|inhibition of gerfelin synthesis|down-regulation of gerfelin biosynthetic process|down regulation of gerfelin anabolism|downregulation of gerfelin biosynthetic process|downregulation of gerfelin synthesis|down regulation of gerfelin biosynthesis|negative regulation of gerfelin biosynthesis|down regulation of gerfelin biosynthetic process|downregulation of gerfelin anabolism|inhibition of gerfelin biosynthetic process|inhibition of gerfelin biosynthesis|down regulation of gerfelin formation|inhibition of gerfelin anabolism|down-regulation of gerfelin anabolism|negative regulation of gerfelin anabolism|downregulation of gerfelin biosynthesis|negative regulation of gerfelin synthesis|downregulation of gerfelin formation|negative regulation of gerfelin formation						di	2012-05-22T04:50:05Z						biological_process											owl:Class	
GO:2000770	biolink:NamedThing	negative regulation of establishment or maintenance of cell polarity regulating cell shape	Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.	got7fsn_ti							mah	2011-06-22T01:56:53Z						biological_process											owl:Class	
GO:2001051	biolink:NamedThing	positive regulation of tendon cell differentiation	Any process that activates or increases the frequency, rate or extent of tendon cell differentiation.	got7fsn_ti	positive regulation of muscle attachment cell differentiation|positive regulation of tenocyte differentiation						yaf	2011-09-01T09:20:42Z						biological_process											owl:Class	
GO:0099509	biolink:NamedThing	regulation of presynaptic cytosolic calcium ion concentration	Any process that regulates the concentration of calcium in the presynaptic cytosol.	got7fsn_ti	regulation of presynaptic cytosolic calcium levels													biological_process											owl:Class	
GO:1900667	biolink:NamedThing	regulation of endocrocin biosynthetic process	Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process.	got7fsn_ti	regulation of endocrocin synthesis|regulation of endocrocin anabolism|regulation of endocrocin biosynthesis|regulation of endocrocin formation						di	2012-05-22T04:16:04Z						biological_process											owl:Class	
GO:0021936	biolink:NamedThing	regulation of cerebellar granule cell precursor proliferation	The process that modulates the frequency, rate or extent of granule cell precursor proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0009050	biolink:NamedThing	glycopeptide catabolic process	The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide.	got7fsn_ti	glycopeptide breakdown|glycopeptide catabolism|glycopeptide degradation													biological_process											owl:Class	
GO:0015527	biolink:NamedThing	glycerol-phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out).	got7fsn_ti														molecular_function											owl:Class	
CHEBI:32395	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900857	biolink:NamedThing	positive regulation of fumitremorgin B biosynthetic process	Any process that activates or increases the frequency, rate or extent of fumitremorgin B biosynthetic process.	got7fsn_ti	up-regulation of fumitremorgin B biosynthetic process|up regulation of fumitremorgin B biosynthetic process|upregulation of fumitremorgin B biosynthetic process						di	2012-06-07T09:51:09Z						biological_process											owl:Class	
GO:0071525	biolink:NamedThing	pyrrolysine metabolic process	The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.	got7fsn_ti	monomethylamine methyltransferase cofactor lysine adduct metabolic process|pyrrolysine metabolism						mah	2010-01-07T02:44:49Z						biological_process											owl:Class	
GO:0046098	biolink:NamedThing	guanine metabolic process	The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.	got7fsn_ti	guanine metabolism													biological_process											owl:Class	
GO:0033804	biolink:NamedThing	obsolete glycine/sarcosine N-methyltransferase activity	OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine, and S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.	got7fsn_ti	S-adenosyl-L-methionine:sarcosine N-methyltransferase activity|glycine-sarcosine methyltransferase activity|GSMT|ApGSMT|glycine/sarcosine N-methyltransferase activity|glycine sarcosine N-methyltransferase activity|GMT				This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052730|GO:0017174				True				molecular_function											owl:Class	
GO:1902289	biolink:NamedThing	negative regulation of defense response to oomycetes	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes.	got7fsn_ti	down regulation of defense response to oomycetes|inhibition of defense response to oomycetes|down-regulation of defense response to oomycetes|downregulation of defense response to oomycetes						ms	2013-07-09T13:45:37Z						biological_process											owl:Class	
GO:0070730	biolink:NamedThing	cAMP transport	The directed movement of cyclic AMP (cAMP), into, out of or within a cell.	got7fsn_ti	cyclic AMP transport						mah	2009-06-17T03:53:45Z						biological_process											owl:Class	
GO:1903634	biolink:NamedThing	negative regulation of leucine-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity.	got7fsn_ti	down-regulation of leucyl-transfer RNA synthetase activity|inhibition of leucine translase activity|down-regulation of L-leucine:tRNALeu ligase (AMP-forming)|negative regulation of leucine-tRNA synthetase activity|negative regulation of leucine translase activity|down regulation of L-leucine:tRNALeu ligase (AMP-forming)|down-regulation of leucine translase activity|down regulation of leucyl-tRNA synthetase activity|inhibition of leucyl-tRNA synthetase activity|inhibition of leucine-tRNA synthetase activity|inhibition of leucyl-transfer RNA synthetase activity|downregulation of leucyl-transfer RNA synthetase activity|down regulation of leucine-tRNA ligase activity|down-regulation of leucyl-transfer ribonucleic acid synthetase activity|negative regulation of leucyl-tRNA synthetase activity|down regulation of leucyl-transfer ribonucleate synthetase activity|down regulation of leucine-tRNA synthetase activity|down-regulation of leucyl-tRNA synthetase activity|negative regulation of leucyl-transfer RNA synthetase activity|down-regulation of leucine-tRNA ligase activity|negative regulation of leucyl-transfer ribonucleic acid synthetase activity|downregulation of leucine-tRNA synthetase activity|inhibition of leucyl-transfer ribonucleic acid synthetase activity|down regulation of leucyl-transfer RNA synthetase activity|negative regulation of leucyl-transfer ribonucleate synthetase activity|downregulation of leucine-tRNA ligase activity|down regulation of leucine translase activity|downregulation of leucine translase activity|downregulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucyl-transfer ribonucleate synthetase activity|inhibition of leucyl-transfer ribonucleate synthetase activity|negative regulation of L-leucine:tRNALeu ligase (AMP-forming)|downregulation of leucyl-tRNA synthetase activity|down-regulation of leucine-tRNA synthetase activity|downregulation of L-leucine:tRNALeu ligase (AMP-forming)|inhibition of leucine-tRNA ligase activity|inhibition of L-leucine:tRNALeu ligase (AMP-forming)|down regulation of leucyl-transfer ribonucleic acid synthetase activity|downregulation of leucyl-transfer ribonucleate synthetase activity						sl	2014-11-20T00:24:56Z						biological_process											owl:Class	
GO:1902521	biolink:NamedThing	response to etoposide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:44:22Z						biological_process											owl:Class	
GO:0016352	biolink:NamedThing	obsolete insecticide susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	insecticide susceptibility/resistance			GO:0017085	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0005837	biolink:NamedThing	obsolete 26S proteasome	OBSOLETE. A large multisubunit protease found in the cytosol that recognizes, unfolds, and digests protein substrates that have been marked for degradation by the attachment of a ubiquitin group. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: the ATP-dependent 19S caps are believed to unfold substrates and feed them to the actual protease, the 20S proteasome.	got7fsn_ti	26S proteasome				This term was made obsolete because its definition was inaccurate.	GO:0000502				True				cellular_component											owl:Class	
GO:0046757	biolink:NamedThing	obsolete lytic virus budding from ER membrane	OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host endoplasmic reticulum membrane system, resulting in envelopment of the virus and cell lysis.	got7fsn_ti	lytic endoplasmic reticulum membrane viral budding|lytic ER membrane viral budding|lytic virus budding from ER membrane|lytic viral budding from ER membrane				This term was made obsolete because it does not appear to correspond to a real biological process.					True				biological_process											owl:Class	
GO:0004700	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030969	biolink:NamedThing	obsolete mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response	OBSOLETE. The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby increasing both the translational efficiency of the processed mRNA and the activity of the protein it encodes.	got7fsn_ti	UFP-specific transcription factor mRNA processing during unfolded protein response|unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor|XBP1 mRNA splicing, via endonucleolytic cleavage and ligation|UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum UPR|unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase|XBP1 mRNA splicing|HAC1 mRNA splicing|unconventional mRNA splicing involved in UPR|non-spliceosomal mRNA splicing in the unfolded protein response pathway|XBP1 mRNA splicing under conditions of endoplasmic reticulum (ER) stress|UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response|unconventional splicing of XBP1 mRNA|spliceosome-independent UFP-specific transcription factor mRNA processing|UFP-specific transcription factor mRNA processing involved in ER UPR|UFP-specific transcription factor mRNA processing involved in ER unfolded protein response|IRE1-mediated XBP-1 mRNA splicing|Ire1p-mediated HAC-1 mRNA splicing				The reason for obsoletion is that this process represent a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498).	GO:0036498				True				biological_process											owl:Class	
GO:1903536	biolink:NamedThing	positive regulation of lactose biosynthetic process	Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process.	got7fsn_ti	upregulation of lactose anabolism|activation of lactose biosynthetic process|activation of lactose anabolism|positive regulation of lactose biosynthesis|up regulation of lactose synthesis|upregulation of lactose synthesis|up regulation of lactose anabolism|upregulation of lactose biosynthetic process|up-regulation of lactose formation|positive regulation of lactose synthesis|up-regulation of lactose anabolism|up-regulation of lactose biosynthetic process|up-regulation of lactose biosynthesis|positive regulation of lactose anabolism|positive regulation of lactose formation|upregulation of lactose biosynthesis|activation of lactose synthesis|up regulation of lactose formation|up regulation of lactose biosynthetic process|up regulation of lactose biosynthesis|up-regulation of lactose synthesis|activation of lactose formation|activation of lactose biosynthesis|upregulation of lactose formation						mr	2014-10-08T16:26:29Z						biological_process											owl:Class	
GO:0051791	biolink:NamedThing	medium-chain fatty acid metabolic process	The chemical reactions and pathways involving medium-chain fatty acids, any fatty acid with a chain length of between C6 and C12.	got7fsn_ti	medium chain fatty acid metabolism|medium chain fatty acid metabolic process|medium-chain fatty acid metabolism													biological_process											owl:Class	
GO:0010252	biolink:NamedThing	auxin homeostasis	A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation.	got7fsn_ti														biological_process											owl:Class	
GO:0097299	biolink:NamedThing	obsolete cysteine-type endopeptidase activity involved in plant-type hypersensitive response	OBSOLETE. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to plant-type hypersensitive response, the rapid, localized death of plant cells in response to invasion by a pathogen.	got7fsn_ti	metacaspase activity involved in plant-type hypersensitive response				This term was obsoleted because it represents a GO-CAM model.		pr	2012-05-04T02:09:55Z		True				molecular_function											owl:Class	
GO:2001252	biolink:NamedThing	positive regulation of chromosome organization	Any process that activates or increases the frequency, rate or extent of chromosome organization.	got7fsn_ti	positive regulation of nuclear genome maintenance|positive regulation of chromosome organisation|positive regulation of maintenance of genome integrity|positive regulation of chromosome organization and biogenesis						yaf	2011-12-02T02:01:26Z						biological_process											owl:Class	
GO:1902770	biolink:NamedThing	negative regulation of choline O-acetyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity.	got7fsn_ti	negative regulation of acetyl-CoA:choline O-acetyltransferase activity|down-regulation of acetyl-CoA:choline O-acetyltransferase activity|downregulation of CHOACTase activity|down regulation of choline acetylase activity|downregulation of choline O-acetyltransferase activity|down-regulation of CHOACTase activity|negative regulation of choline acetylase activity|down regulation of acetyl-CoA:choline O-acetyltransferase activity|downregulation of choline acetyltransferase activity|inhibition of choline acetyltransferase activity|inhibition of CHOACTase activity|downregulation of choline acetylase activity|down-regulation of choline O-acetyltransferase activity|negative regulation of choline acetyltransferase activity|down regulation of choline acetyltransferase activity|inhibition of choline O-acetyltransferase activity|down-regulation of choline acetyltransferase activity|down-regulation of choline acetylase activity|inhibition of choline acetylase activity|down regulation of CHOACTase activity|negative regulation of CHOACTase activity|downregulation of acetyl-CoA:choline O-acetyltransferase activity|inhibition of acetyl-CoA:choline O-acetyltransferase activity|down regulation of choline O-acetyltransferase activity						mr	2014-03-11T18:56:50Z						biological_process											owl:Class	
GO:0031228	biolink:NamedThing	intrinsic component of Golgi membrane	The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to Golgi membrane													cellular_component											owl:Class	
GO:1900778	biolink:NamedThing	fumiquinazoline A biosynthetic process	The chemical reactions and pathways resulting in the formation of fumiquinazoline A.	got7fsn_ti	fumiquinazoline A formation|fumiquinazoline A synthesis|fumiquinazoline A biosynthesis|fumiquinazoline A anabolism						di	2012-06-04T09:30:25Z						biological_process											owl:Class	
GO:1901189	biolink:NamedThing	positive regulation of ephrin receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway.	got7fsn_ti	up regulation of ephrin receptor signaling pathway|activation of Eph receptor signaling pathway|activation of ephrin receptor signaling pathway|activation of Eph receptor signalling pathway|upregulation of Eph receptor signalling pathway|up regulation of Eph receptor signalling pathway|up regulation of Eph receptor signaling pathway|up-regulation of ephrin receptor signaling pathway|up-regulation of Eph receptor signalling pathway|upregulation of ephrin receptor signaling pathway|upregulation of Eph receptor signaling pathway|positive regulation of Eph receptor signalling pathway|positive regulation of Eph receptor signaling pathway|up-regulation of Eph receptor signaling pathway						rl	2012-07-24T07:42:21Z						biological_process											owl:Class	
GO:1905587	biolink:NamedThing	positive regulation of outer hair cell apoptotic process	Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process.	got7fsn_ti	up-regulation of outer hair cell apoptotic process|up regulation of outer hair cell apoptosis|positive regulation of outer hair cell apoptosis|activation of outer hair cell apoptotic process|upregulation of outer hair cell apoptotic process|up-regulation of cochlear outer hair cell apoptotic process|activation of cochlear outer hair cell apoptotic process|up-regulation of cochlear outer hair cell apoptosis|positive regulation of cochlear outer hair cell apoptotic process|positive regulation of cochlear outer hair cell apoptosis|upregulation of cochlear outer hair cell apoptosis|up regulation of cochlear outer hair cell apoptotic process|up-regulation of outer hair cell apoptosis|activation of outer hair cell apoptosis|up regulation of outer hair cell apoptotic process|up regulation of cochlear outer hair cell apoptosis|upregulation of outer hair cell apoptosis|upregulation of cochlear outer hair cell apoptotic process|activation of cochlear outer hair cell apoptosis						sl	2016-10-24T22:35:51Z						biological_process											owl:Class	
GO:1901430	biolink:NamedThing	positive regulation of syringal lignin biosynthetic process	Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process.	got7fsn_ti	up regulation of syringal lignin biosynthesis|up regulation of syringal lignin formation|positive regulation of syringal lignin biosynthesis|up-regulation of syringal lignin biosynthesis|activation of syringal lignin formation|positive regulation of S-lignin biosynthetic process|positive regulation of syringal lignin synthesis|up regulation of S-lignin biosynthetic process|up-regulation of syringal lignin formation|activation of S-lignin biosynthetic process|up regulation of syringal lignin synthesis|activation of syringal lignin synthesis|up-regulation of syringal lignin anabolism|activation of syringal lignin biosynthetic process|up-regulation of syringal lignin synthesis|up-regulation of S-lignin biosynthetic process|upregulation of syringal lignin biosynthesis|upregulation of syringal lignin biosynthetic process|activation of syringal lignin biosynthesis|upregulation of syringal lignin synthesis|upregulation of S-lignin biosynthetic process|up-regulation of syringal lignin biosynthetic process|upregulation of syringal lignin formation|positive regulation of syringal lignin anabolism|up regulation of syringal lignin biosynthetic process|upregulation of syringal lignin anabolism|up regulation of syringal lignin anabolism|positive regulation of syringal lignin formation|activation of syringal lignin anabolism						tb	2012-10-01T20:15:09Z						biological_process											owl:Class	
GO:1900218	biolink:NamedThing	negative regulation of apoptotic process involved in metanephric nephron tubule development	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.	got7fsn_ti	down regulation of apoptotic process of metanephric nephron tubule development|down regulation of type I programmed cell death of metanephric nephron tubule development|negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development|downregulation of apoptotic program of metanephric nephron tubule development|downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development|down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development|down regulation of apoptotic process involved in metanephric nephron tubule development|inhibition of apoptotic process involved in metanephric nephron tubule development|down-regulation of apoptosis of metanephric nephron tubule development|inhibition of apoptotic program of metanephric nephron tubule development|negative regulation of type I programmed cell death of metanephric nephron tubule development|down-regulation of apoptotic cell death of metanephric nephron tubule development|downregulation of apoptotic process of metanephric nephron tubule development|negative regulation of apoptotic process of metanephric nephron tubule development|downregulation of programmed cell death by apoptosis of metanephric nephron tubule development|downregulation of apoptotic programmed cell death of metanephric nephron tubule development|down regulation of apoptotic program of metanephric nephron tubule development|down regulation of programmed cell death by apoptosis of metanephric nephron tubule development|negative regulation of apoptotic program of metanephric nephron tubule development|downregulation of apoptotic process involved in metanephric nephron tubule development|negative regulation of apoptosis of metanephric nephron tubule development|inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development|inhibition of apoptosis of metanephric nephron tubule development|inhibition of apoptotic programmed cell death of metanephric nephron tubule development|down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|down regulation of apoptosis of metanephric nephron tubule development|down-regulation of apoptotic programmed cell death of metanephric nephron tubule development|down-regulation of type I programmed cell death of metanephric nephron tubule development|down-regulation of apoptotic process involved in metanephric nephron tubule development|down regulation of apoptotic programmed cell death of metanephric nephron tubule development|inhibition of apoptotic cell death of metanephric nephron tubule development|inhibition of type I programmed cell death of metanephric nephron tubule development|inhibition of apoptotic process of metanephric nephron tubule development|inhibition of programmed cell death by apoptosis of metanephric nephron tubule development|down regulation of apoptotic cell death of metanephric nephron tubule development|negative regulation of apoptotic cell death of metanephric nephron tubule development|down-regulation of apoptotic process of metanephric nephron tubule development|downregulation of type I programmed cell death of metanephric nephron tubule development|down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|down-regulation of apoptotic program of metanephric nephron tubule development|negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|downregulation of apoptosis of metanephric nephron tubule development|negative regulation of apoptotic programmed cell death of metanephric nephron tubule development|downregulation of apoptotic cell death of metanephric nephron tubule development						yaf	2012-03-22T10:54:01Z						biological_process											owl:Class	
GO:1905809	biolink:NamedThing	negative regulation of synapse organization	Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization.	got7fsn_ti	down-regulation of synapse morphogenesis|down-regulation of synapse development|downregulation of synapse organization|down regulation of synapse organisation|negative regulation of synapse development|down-regulation of synapse organisation|down regulation of synapse organization|negative regulation of synapse organisation|inhibition of synapse organization|inhibition of synapse organisation|downregulation of synapse morphogenesis|down regulation of synapse organization and biogenesis|downregulation of synapse organization and biogenesis|down-regulation of synapse organization and biogenesis|downregulation of synapse development|inhibition of synapse morphogenesis|negative regulation of synapse morphogenesis|inhibition of synapse organization and biogenesis|down-regulation of synapse organization|down regulation of synapse morphogenesis|downregulation of synapse organisation|negative regulation of synapse organization and biogenesis|down regulation of synapse development|inhibition of synapse development						tb	2017-01-11T22:03:41Z						biological_process											owl:Class	
GO:1905866	biolink:NamedThing	positive regulation of Atg1/ULK1 kinase complex assembly	Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.	got7fsn_ti	positive regulation of ATG1-ATG13 complex assembly|up-regulation of ATG1/ULK1 kinase complex formation|upregulation of ATG1 kinase complex formation|positive regulation of ULK1-ATG13-FIP200 complex assembly|up-regulation of ATG1-ATG13 complex assembly|up-regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ULK1 signaling complex formation|up-regulation of ATG1/ULK1 signaling complex formation|upregulation of ATG1-ATG13 complex assembly|up regulation of ULK1 signaling complex formation|up-regulation of ATG1/ULK1 signaling complex assembly|positive regulation of Atg1p signalling complex formation|up-regulation of ULK1 signaling complex assembly|upregulation of ULK1 signaling complex assembly|activation of ATG1 kinase complex formation|up-regulation of Atg1p signalling complex assembly|upregulation of Atg1p signalling complex formation|activation of Atg1p signalling complex assembly|positive regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ATG1 kinase complex assembly|positive regulation of ATG1 kinase complex assembly|up-regulation of ATG1-ATG13 complex formation|upregulation of ATG1/ULK1 kinase complex assembly|up regulation of ULK1-ATG13-FIP200 complex assembly|up regulation of Atg1p signalling complex formation|upregulation of ATG1/ULK1 signaling complex formation|upregulation of ULK1 signaling complex formation|upregulation of ULK1-ATG13-RB1CC1 complex formation|up regulation of ULK1-ATG13-RB1CC1 complex assembly|up regulation of ATG1/ULK1 signaling complex formation|up regulation of ATG1 kinase complex assembly|positive regulation of ATG1/ULK1 signaling complex formation|up regulation of ULK1-ATG13-RB1CC1 complex formation|upregulation of ULK1-ATG13-FIP200 complex assembly|up-regulation of ULK1-ATG13-RB1CC1 complex assembly|up-regulation of ATG1/ULK1 kinase complex assembly|up regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of Atg1p signalling complex formation|up-regulation of ULK1-ATG13-FIP200 complex assembly|upregulation of ULK1-ATG13-FIP200 complex formation|activation of ULK1 signaling complex formation|up regulation of ATG1 kinase complex formation|activation of ATG1-ATG13 complex assembly|activation of ULK1 signaling complex assembly|activation of ULK1-ATG13-RB1CC1 complex formation|activation of ULK1-ATG13-FIP200 complex formation|activation of ULK1-ATG13-FIP200 complex assembly|positive regulation of ULK1-ATG13-RB1CC1 complex formation|up regulation of ATG1/ULK1 signaling complex assembly|up regulation of ATG1/ULK1 kinase complex assembly|upregulation of ATG1 kinase complex assembly|activation of ATG1/ULK1 kinase complex assembly|up-regulation of ATG1 kinase complex formation|upregulation of ATG1-ATG13 complex formation|activation of ATG1 kinase complex assembly|up regulation of ATG1-ATG13 complex formation|up regulation of Atg1p signalling complex assembly|positive regulation of ATG1/ULK1 signaling complex assembly|up regulation of ULK1 signaling complex assembly|activation of ULK1-ATG13-RB1CC1 complex assembly|activation of ATG1/ULK1 signaling complex assembly|positive regulation of ATG1/ULK1 kinase complex formation|up regulation of ATG1/ULK1 kinase complex formation|upregulation of ULK1-ATG13-RB1CC1 complex assembly|positive regulation of ATG1 kinase complex formation|activation of ATG1/ULK1 kinase complex formation|up-regulation of ULK1-ATG13-RB1CC1 complex formation|positive regulation of ULK1 signaling complex assembly|up regulation of ATG1-ATG13 complex assembly|activation of Atg1p signalling complex formation|activation of ATG1-ATG13 complex formation|upregulation of Atg1p signalling complex assembly|positive regulation of Atg1p signalling complex assembly|positive regulation of ATG1-ATG13 complex formation|positive regulation of ULK1-ATG13-RB1CC1 complex assembly|activation of ATG1/ULK1 signaling complex formation|positive regulation of ULK1 signaling complex formation|upregulation of ATG1/ULK1 kinase complex formation|upregulation of ATG1/ULK1 signaling complex assembly						pr	2017-01-26T13:23:44Z						biological_process											owl:Class	
GO:0045762	biolink:NamedThing	positive regulation of adenylate cyclase activity	Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.	got7fsn_ti	up regulation of adenylate cyclase activity|adenylate cyclase activator|positive regulation of adenylyl cyclase activity|up-regulation of adenylate cyclase activity|stimulation of adenylate cyclase activity|upregulation of adenylate cyclase activity													biological_process											owl:Class	
GO:1900521	biolink:NamedThing	regulation of response to amylopectin	Any process that modulates the frequency, rate or extent of response to amylopectin.	got7fsn_ti							tt	2012-05-02T04:13:51Z						biological_process											owl:Class	
GO:0033049	biolink:NamedThing	clavulanic acid metabolic process	The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.	got7fsn_ti	clavulanic acid metabolism													biological_process											owl:Class	
GO:1905695	biolink:NamedThing	positive regulation of phosphatidic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.	got7fsn_ti	up-regulation of phosphatidic acid anabolism|positive regulation of phosphatidic acid biosynthesis|positive regulation of phosphatidic acid anabolism|upregulation of phosphatidic acid anabolism|activation of phosphatidic acid synthesis|up regulation of phosphatidic acid anabolism|activation of phosphatidic acid biosynthetic process|up-regulation of phosphatidic acid biosynthesis|upregulation of phosphatidic acid biosynthesis|upregulation of phosphatidic acid formation|activation of phosphatidic acid anabolism|up-regulation of phosphatidic acid biosynthetic process|activation of phosphatidic acid formation|up regulation of phosphatidic acid biosynthesis|up-regulation of phosphatidic acid formation|up regulation of phosphatidic acid biosynthetic process|positive regulation of phosphatidic acid formation|positive regulation of phosphatidic acid synthesis|activation of phosphatidic acid biosynthesis|up-regulation of phosphatidic acid synthesis|up regulation of phosphatidic acid formation|upregulation of phosphatidic acid synthesis|up regulation of phosphatidic acid synthesis|upregulation of phosphatidic acid biosynthetic process						bc	2016-11-14T14:48:24Z						biological_process											owl:Class	
GO:0032489	biolink:NamedThing	regulation of Cdc42 protein signal transduction	Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:1901708	biolink:NamedThing	(+)-3'-hydroxylarreatricin biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin.	got7fsn_ti	(+)-3'-hydroxylarreatricin formation|(+)-3'-hydroxylarreatricin biosynthesis|(+)-3'-hydroxylarreatricin anabolism|(+)-3'-hydroxylarreatricin synthesis						ms	2012-12-19T14:39:32Z						biological_process											owl:Class	
GO:1903862	biolink:NamedThing	positive regulation of oxidative phosphorylation	Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation.	got7fsn_ti	positive regulation of respiratory-chain phosphorylation|upregulation of respiratory-chain phosphorylation|up-regulation of respiratory-chain phosphorylation|up regulation of respiratory-chain phosphorylation|activation of respiratory-chain phosphorylation|activation of oxidative phosphorylation|up regulation of oxidative phosphorylation|up-regulation of oxidative phosphorylation|upregulation of oxidative phosphorylation						sl	2015-02-02T23:40:22Z						biological_process											owl:Class	
GO:0019633	biolink:NamedThing	shikimate catabolic process	The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.	got7fsn_ti	shikimate breakdown|shikimate catabolism|shikimate degradation											MetaCyc:SHIKIMATEDEG-PWY		biological_process											owl:Class	
GO:0075175	biolink:NamedThing	obsolete positive regulation of cAMP-mediated signaling in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont cAMP-mediated signal transduction in response to host|positive regulation of cAMP-mediated signal transduction in response to host|positive regulation of cAMP-mediated signalling in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0033350	biolink:NamedThing	apiose biosynthetic process	The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.	got7fsn_ti	apiose anabolism|apiose synthesis|apiose formation|apiose biosynthesis													biological_process											owl:Class	
GO:0009695	biolink:NamedThing	jasmonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative.	got7fsn_ti	jasmonic acid anabolism|jasmonic acid formation|jasmonic acid synthesis|jasmonic acid biosynthesis											MetaCyc:PWY-735		biological_process											owl:Class	
GO:2000135	biolink:NamedThing	obsolete positive regulation of regulation of secondary heart field cardioblast proliferation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of secondary heart field cardioblast proliferation.	got7fsn_ti	positive regulation of regulation of secondary heart field cardioblast proliferation|positive regulation of regulation of second heart field cardioblast proliferation				This term was made obsolete because it makes no sense and was added in error.		dph	2010-09-29T12:40:37Z		True				biological_process											owl:Class	
UBERON:0006698	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008245	biolink:NamedThing	obsolete lysosomal membrane hydrogen-transporting ATPase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lysosomal membrane hydrogen-transporting ATPase|V-ATPase				This term was made obsolete because more specific terms were created.	GO:0046611				True				cellular_component											owl:Class	
GO:1903472	biolink:NamedThing	negative regulation of mitotic actomyosin contractile ring contraction	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction.	got7fsn_ti	downregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|negative regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|negative regulation of mitotic actomyosin contractile ring constriction|down-regulation of mitotic actomyosin contractile ring contraction|inhibition of mitotic actomyosin contractile ring contraction|down regulation of mitotic actomyosin contractile ring contraction|down regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of mitotic actomyosin contractile ring contraction|inhibition of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|negative regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/21855					vw	2014-09-23T14:10:38Z						biological_process											owl:Class	
GO:0032463	biolink:NamedThing	negative regulation of protein homooligomerization	Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.	got7fsn_ti	down-regulation of protein homooligomerization|inhibition of protein homooligomerization|down regulation of protein homooligomerization|downregulation of protein homooligomerization													biological_process											owl:Class	
GO:1903175	biolink:NamedThing	fatty alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of fatty alcohol.	got7fsn_ti	fatty alcohol anabolism|fatty alcohol biosynthesis|fatty alcohol synthesis|fatty alcohol formation						tt	2014-07-14T01:51:54Z						biological_process											owl:Class	
GO:0002120	biolink:NamedThing	obsolete predatory behavior	OBSOLETE. Aggressive behavior involving attack on prey by a predator.	got7fsn_ti	predatory aggressive behavior|predatory aggression	https://github.com/geneontology/go-ontology/issues/18568			This term was obsoleted because it is outside the scope of GO.					True				biological_process											owl:Class	
CL:0000806	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905888	biolink:NamedThing	negative regulation of cellular response to very-low-density lipoprotein particle stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.	got7fsn_ti	inhibition of cellular response to VLDL particle stimulus|down-regulation of cellular response to VLDL particle stimulus|negative regulation of cellular response to VLDL particle stimulus|down-regulation of cellular response to very-low-density lipoprotein particle stimulus|downregulation of cellular response to very-low-density lipoprotein particle stimulus|inhibition of cellular response to very-low-density lipoprotein particle stimulus|down regulation of cellular response to VLDL particle stimulus|down regulation of cellular response to very-low-density lipoprotein particle stimulus|downregulation of cellular response to VLDL particle stimulus						bc	2017-02-01T10:09:25Z						biological_process											owl:Class	
GO:1903592	biolink:NamedThing	positive regulation of lysozyme activity	Any process that activates or increases the frequency, rate or extent of lysozyme activity.	got7fsn_ti	up-regulation of PR1-lysozyme|upregulation of mucopeptide N-acetylmuramoylhydrolase activity|upregulation of muramidase activity|positive regulation of 1,4-N-acetylmuramidase activity|activation of lysozyme g|up regulation of lysozyme activity|activation of globulin G1|up regulation of lysozyme g|up regulation of mucopeptide glucohydrolase activity|activation of mucopeptide glucohydrolase activity|up regulation of globulin G1|positive regulation of lysozyme g|up-regulation of lysozyme g|upregulation of lysozyme activity|up regulation of mucopeptide N-acetylmuramoylhydrolase activity|up-regulation of mucopeptide glucohydrolase activity|up regulation of L-7001|up-regulation of L-7001|positive regulation of peptidoglycan N-acetylmuramoylhydrolase activity|activation of mucopeptide N-acetylmuramoylhydrolase activity|up-regulation of globulin G|up-regulation of muramidase activity|up-regulation of mucopeptide N-acetylmuramoylhydrolase activity|activation of globulin G|activation of N,O-diacetylmuramidase activity|upregulation of peptidoglycan N-acetylmuramoylhydrolase activity|positive regulation of PR1-lysozyme|activation of L-7001|upregulation of L-7001|up regulation of muramidase activity|activation of peptidoglycan N-acetylmuramoylhydrolase activity|up-regulation of lysozyme activity|positive regulation of globulin G|upregulation of lysozyme g|upregulation of 1,4-N-acetylmuramidase activity|upregulation of globulin G|upregulation of PR1-lysozyme|positive regulation of muramidase activity|upregulation of N,O-diacetylmuramidase activity|upregulation of mucopeptide glucohydrolase activity|up-regulation of globulin G1|positive regulation of L-7001|positive regulation of mucopeptide glucohydrolase activity|up regulation of 1,4-N-acetylmuramidase activity|activation of lysozyme activity|up regulation of N,O-diacetylmuramidase activity|up regulation of PR1-lysozyme|activation of muramidase activity|positive regulation of N,O-diacetylmuramidase activity|upregulation of globulin G1|up-regulation of peptidoglycan N-acetylmuramoylhydrolase activity|positive regulation of globulin G1|activation of 1,4-N-acetylmuramidase activity|positive regulation of mucopeptide N-acetylmuramoylhydrolase activity|activation of PR1-lysozyme|up regulation of peptidoglycan N-acetylmuramoylhydrolase activity|up-regulation of N,O-diacetylmuramidase activity|up regulation of globulin G|up-regulation of 1,4-N-acetylmuramidase activity						mr	2014-11-05T21:41:39Z						biological_process											owl:Class	
GO:1903869	biolink:NamedThing	negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.	got7fsn_ti	down-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|downregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|inhibition of MetF|downregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|inhibition of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|negative regulation of MetF|inhibition of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|downregulation of N5,N10-methylenetetrahydrofolate reductase activity|negative regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|negative regulation of methylenetetrahydrofolate reductase (NADPH2)|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|negative regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|down regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|down-regulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|downregulation of 5,10-CH(2)-H(4)folate reductase activity|inhibition of methylenetetrahydrofolate reductase (NADPH2)|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|inhibition of 5,10-CH(2)-H(4)folate reductase activity|down-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|inhibition of methylenetetrahydrofolate reductase (NADPH(2)) activity|downregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|downregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|inhibition of 5,10-methylenetetrahydropteroylglutamate reductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|negative regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|downregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|downregulation of N5,10-methylenetetrahydrofolate reductase activity|downregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|down regulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of N5,N10-methylenetetrahydrofolate reductase activity|down regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|inhibition of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|down-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down regulation of N5,N10-methylenetetrahydrofolate reductase activity|down-regulation of 5,10-CH2-H4folate reductase activity|down-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|negative regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of MetF|negative regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|inhibition of 5-methyltetrahydrofolate:NAD oxidoreductase activity|downregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|inhibition of 5,10-CH2-H4folate reductase activity|down regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|negative regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|downregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down-regulation of MetF|negative regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|negative regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|negative regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|downregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|negative regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of methylenetetrahydrofolate reductase [NAD(P)H]|down regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|down regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|inhibition of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of 5,10-CH2-H4folate reductase activity|down-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|inhibition of methylenetetrahydrofolate reductase (NAD(P)H) activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|inhibition of methylenetetrahydrofolate reductase [NAD(P)H]|down-regulation of N5,N10-methylenetetrahydrofolate reductase activity|down regulation of MetF|down-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|downregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|downregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|inhibition of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|downregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|down regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|down regulation of N5,10-methylenetetrahydrofolate reductase activity|negative regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|inhibition of N5,N10-methylenetetrahydrofolate reductase activity|down regulation of methylenetetrahydrofolate reductase (NADPH2)|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|inhibition of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of N5,10-methylenetetrahydrofolate reductase activity|negative regulation of N5,10-methylenetetrahydrofolate reductase activity|negative regulation of 5,10-CH(2)-H(4)folate reductase activity|down-regulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of methylenetetrahydrofolate reductase [NAD(P)H]|downregulation of 5,10-CH2-H4folate reductase activity|down-regulation of 5,10-CH(2)-H(4)folate reductase activity|inhibition of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|negative regulation of 5,10-CH2-H4folate reductase activity|downregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|inhibition of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity						rph	2015-02-05T13:26:25Z						biological_process											owl:Class	
GO:1902628	biolink:NamedThing	positive regulation of assembly of large subunit precursor of preribosome	Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome.	got7fsn_ti	activation of preribosome, large subunit precursor formation|activation of 66S preribosome formation|positive regulation of preribosome, large subunit precursor formation|positive regulation of 66S preribosome assembly|up-regulation of assembly of large subunit precursor of preribosome|upregulation of preribosome, large subunit precursor formation|upregulation of assembly of large subunit precursor of preribosome|up-regulation of 66S preribosome assembly|up regulation of assembly of large subunit precursor of preribosome|up regulation of 66S preribosome assembly|upregulation of 66S preribosome formation|activation of 66S preribosome assembly|up regulation of 66S preribosome formation|activation of assembly of large subunit precursor of preribosome|upregulation of 66S preribosome assembly|up regulation of preribosome, large subunit precursor formation|up-regulation of preribosome, large subunit precursor formation|up-regulation of 66S preribosome formation|positive regulation of 66S preribosome formation						tb	2014-01-16T22:11:55Z						biological_process											owl:Class	
GO:1901705	biolink:NamedThing	L-isoleucine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-isoleucine.	got7fsn_ti	L-isoleucine anabolism|L-isoleucine formation|L-isoleucine biosynthesis|L-isoleucine synthesis						pde	2012-12-13T23:32:56Z						biological_process											owl:Class	
GO:1905549	biolink:NamedThing	obsolete positive regulation of subtelomeric heterochromatin assembly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of subtelomeric heterochromatin assembly.	got7fsn_ti	activation of telomeric heterochromatin assembly|positive regulation of telomeric heterochromatin assembly|upregulation of telomeric heterochromatin formation|up-regulation of telomeric heterochromatin assembly|up regulation of telomeric heterochromatin assembly|up regulation of telomeric heterochromatin formation|up-regulation of telomeric heterochromatin formation|upregulation of telomeric heterochromatin assembly|positive regulation of telomeric heterochromatin formation|activation of telomeric heterochromatin formation	https://github.com/geneontology/go-ontology/issues/19188|https://github.com/geneontology/go-ontology/issues/22027			This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.		nc	2016-10-12T11:18:30Z		True				biological_process											owl:Class	
GO:0006655	biolink:NamedThing	phosphatidylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.	got7fsn_ti	phosphatidylglycerol anabolism|phosphatidylglycerol biosynthesis|phosphatidylglycerol formation|phosphatidylglycerol synthesis													biological_process											owl:Class	
GO:0045194	biolink:NamedThing	obsolete oxidized low-density lipoprotein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of oxidized low-density lipoproteins.	got7fsn_ti	Ox-LDL catabolism|Ox-LDL catabolic process|oxidized low-density lipoprotein catabolism|oxidized low-density lipoprotein breakdown|oxidized low-density lipoprotein catabolic process|oxidized low-density lipoprotein degradation				This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds.					True				biological_process											owl:Class	
GO:0044456	biolink:NamedThing	obsolete synapse part	OBSOLETE. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.	got7fsn_ti	synaptic component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0045202				True		NIF_Subcellular:sao1784069613		cellular_component											owl:Class	
GO:0070434	biolink:NamedThing	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.	got7fsn_ti	positive regulation of NOD2 signaling pathway|positive regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway													biological_process											owl:Class	
GO:1903580	biolink:NamedThing	positive regulation of ATP metabolic process	Any process that activates or increases the frequency, rate or extent of ATP metabolic process.	got7fsn_ti	up-regulation of ATP metabolic process|up regulation of ATP metabolic process|positive regulation of ATP metabolism|upregulation of ATP metabolism|up-regulation of ATP metabolism|upregulation of ATP metabolic process|activation of ATP metabolism|up regulation of ATP metabolism|activation of ATP metabolic process						sl	2014-10-30T19:04:42Z						biological_process											owl:Class	
GO:0016148	biolink:NamedThing	obsolete protein-synthesizing GTPase activity, termination	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	protein-synthesizing GTPase activity, termination				This term was made obsolete because it contains both process and function information.	GO:0006412|GO:0003924|GO:0006415|GO:0008079				True				molecular_function											owl:Class	
GO:1900084	biolink:NamedThing	regulation of peptidyl-tyrosine autophosphorylation	Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.	got7fsn_ti	regulation of receptor tyrosine kinase autophosphorylation|regulation of tyrosine autophosphorylation						bf	2012-02-03T10:17:07Z						biological_process											owl:Class	
GO:0000945	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042806	biolink:NamedThing	fucose binding	Binding to fucose, the pentose 6-deoxygalactose.	got7fsn_ti														molecular_function											owl:Class	
GO:1901094	biolink:NamedThing	negative regulation of protein homotetramerization	Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization.	got7fsn_ti	inhibition of protein homotetramer assembly|inhibition of protein homotetramer biosynthetic process|downregulation of protein homotetramerization|down regulation of protein homotetramer biosynthetic process|down regulation of protein homotetramer formation|down-regulation of protein homotetramer assembly|negative regulation of protein homotetramer formation|downregulation of protein homotetramer formation|down regulation of protein homotetramer assembly|inhibition of protein homotetramer formation|negative regulation of protein homotetramer biosynthetic process|down-regulation of protein homotetramer biosynthesis|down-regulation of protein homotetramerization|inhibition of protein homotetramer biosynthesis|downregulation of protein homotetramer biosynthetic process|negative regulation of protein homotetramer assembly|down-regulation of protein homotetramer biosynthetic process|downregulation of protein homotetramer biosynthesis|down regulation of protein homotetramerization|down regulation of protein homotetramer biosynthesis|inhibition of protein homotetramerization|downregulation of protein homotetramer assembly|negative regulation of protein homotetramer biosynthesis|down-regulation of protein homotetramer formation						pm	2012-07-06T12:57:58Z						biological_process											owl:Class	
GO:1903140	biolink:NamedThing	regulation of establishment of endothelial barrier	Any process that modulates the frequency, rate or extent of establishment of endothelial barrier.	got7fsn_ti							als	2014-07-01T12:12:34Z						biological_process											owl:Class	
GO:0060680	biolink:NamedThing	lateral sprouting involved in ureteric bud morphogenesis	The process in which a branch forms along the side of a ureteric bud.	got7fsn_ti							dph	2009-06-02T02:44:27Z						biological_process											owl:Class	
GO:0046615	biolink:NamedThing	obsolete re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)	OBSOLETE. The resumption of the Saccharomyces mitotic cell division cycle by pheromone-arrested cells that have not mated.	got7fsn_ti	re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)			GO:0000321	This term was made obsolete because there is no evidence that this process is unique to Saccharomyces.					True				biological_process											owl:Class	
GO:1901814	biolink:NamedThing	astaxanthin catabolic process	The chemical reactions and pathways resulting in the breakdown of astaxanthin.	got7fsn_ti	astaxanthin degradation|astaxanthin catabolism|astaxanthin breakdown						yaf	2013-01-22T10:37:03Z						biological_process											owl:Class	
GO:0008498	biolink:NamedThing	obsolete phospholipid scrambling	OBSOLETE. The trans-bilayer migration of phospholipids accelerated by a phospholipid scramblase upon binding calcium ions.	got7fsn_ti	phospholipid scrambling			GO:0017121	This term was made obsolete because it represents a biological process and not a molecular function.					True				molecular_function											owl:Class	
GO:1900304	biolink:NamedThing	negative regulation of laminaritriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport.	got7fsn_ti	down-regulation of laminaritriose transport|inhibition of laminaritriose transport|down regulation of laminaritriose transport|downregulation of laminaritriose transport						tt	2012-04-05T07:57:58Z						biological_process											owl:Class	
GO:1902855	biolink:NamedThing	regulation of non-motile cilium assembly	Any process that modulates the frequency, rate or extent of non-motile cilium assembly.	got7fsn_ti	regulation of nonmotile primary cilia assembly|regulation of nonmotile primary cilium assembly|regulation of immotile primary cilium assembly|regulation of sensory cilium assembly|regulation of sensory cilium biogenesis						kmv	2014-04-02T15:41:57Z						biological_process											owl:Class	
GO:1900717	biolink:NamedThing	negative regulation of violaceol II biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process.	got7fsn_ti	negative regulation of violaceol II synthesis|downregulation of violaceol II biosynthesis|down-regulation of violaceol II synthesis|down-regulation of violaceol II biosynthesis|negative regulation of violaceol II biosynthesis|down regulation of violaceol II formation|negative regulation of violaceol II anabolism|downregulation of violaceol II formation|down-regulation of violaceol II biosynthetic process|downregulation of violaceol II anabolism|inhibition of violaceol II biosynthetic process|down regulation of violaceol II synthesis|down regulation of violaceol II anabolism|inhibition of violaceol II synthesis|inhibition of violaceol II formation|down regulation of violaceol II biosynthetic process|down regulation of violaceol II biosynthesis|inhibition of violaceol II biosynthesis|downregulation of violaceol II biosynthetic process|down-regulation of violaceol II anabolism|down-regulation of violaceol II formation|downregulation of violaceol II synthesis|negative regulation of violaceol II formation|inhibition of violaceol II anabolism						di	2012-05-22T05:05:58Z						biological_process											owl:Class	
GO:0098947	biolink:NamedThing	intrinsic component of postsynaptic endocytic zone membrane	The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to postsynaptic acive zone membrane													cellular_component											owl:Class	
GO:1902164	biolink:NamedThing	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.	got7fsn_ti	upregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|activation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|up regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator						lb	2013-05-22T12:39:29Z						biological_process											owl:Class	
GO:2000089	biolink:NamedThing	positive regulation of mesonephric glomerulus development	Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development.	got7fsn_ti							dph	2010-09-03T06:09:24Z						biological_process											owl:Class	
GO:1902864	biolink:NamedThing	negative regulation of embryonic camera-type eye development	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development.	got7fsn_ti	negative regulation of embryonic eye development|inhibition of embryonic eye development|down-regulation of embryonic camera-type eye development|down-regulation of embryonic eye development|down regulation of embryonic eye development|down regulation of embryonic camera-type eye development|downregulation of embryonic camera-type eye development|inhibition of embryonic camera-type eye development|downregulation of embryonic eye development						mr	2014-04-03T15:24:06Z						biological_process											owl:Class	
GO:0046638	biolink:NamedThing	positive regulation of alpha-beta T cell differentiation	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation.	got7fsn_ti	positive regulation of alpha-beta T lymphocyte differentiation|upregulation of alpha-beta T cell differentiation|up-regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T-lymphocyte differentiation|positive regulation of alpha-beta T cell development|stimulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T-cell differentiation|activation of alpha-beta T cell differentiation|up regulation of alpha-beta T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:2000550	biolink:NamedThing	negative regulation of B cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis.	got7fsn_ti							ebc	2011-04-03T07:25:59Z						biological_process											owl:Class	
GO:1905767	biolink:NamedThing	regulation of double-stranded telomeric DNA binding	Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding.	got7fsn_ti							nc	2016-12-20T15:33:58Z						biological_process											owl:Class	
GO:1902614	biolink:NamedThing	positive regulation of anti-Mullerian hormone signaling pathway	Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway.	got7fsn_ti	up regulation of anti-Mullerian hormone signaling pathway|upregulation of anti-Mullerian hormone signaling pathway|up-regulation of anti-Mullerian hormone signaling pathway|activation of anti-Mullerian hormone signaling pathway						hjd	2014-01-09T15:39:48Z						biological_process											owl:Class	
GO:0071409	biolink:NamedThing	cellular response to cycloheximide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.	got7fsn_ti	cellular response to actidione						mah	2009-12-14T02:57:24Z						biological_process											owl:Class	
GO:1902079	biolink:NamedThing	D-valine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-valine.	got7fsn_ti	D-valine degradation|D-valine catabolism|D-valine breakdown						al	2013-04-23T21:34:29Z						biological_process											owl:Class	
GO:0005568	biolink:NamedThing	obsolete mitochondrial rRNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	mitochondrial rRNA				Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0004584	biolink:NamedThing	obsolete dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity	OBSOLETE. Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide.	got7fsn_ti	oligomannosylsynthase activity|dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase activity|dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase activity	https://github.com/geneontology/go-ontology/issues/16022			The reason for obsoletion is that this activity has been replaced by 4 activities in EC, EC:2.4.1.258, EC:2.4.1.259, EC:2.4.1.260, and EC:2.4.1.261.	GO:0052917|GO:0052925|GO:0052926|GO:0052918				True		MetaCyc:2.4.1.130-RXN|EC:2.4.1.130		molecular_function											owl:Class	
GO:1903655	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter	Any phosphorylation of RNA polymerase II C-terminal domain serine 2 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter.	got7fsn_ti							vw	2014-11-25T11:04:16Z						biological_process											owl:Class	
GO:0045094	biolink:NamedThing	obsolete interleukin-18 beta subunit binding	OBSOLETE. Binding to beta subunit of interleukin-18. IL-18b is a ligand non-binding chain and is required for signaling of IL-18 that binds with IL-18a.	got7fsn_ti	IL-18Rb binding				This term was obsoleted because interleukin-18 is a single polypeptide and has no subunits.					True				molecular_function											owl:Class	
GO:0010929	biolink:NamedThing	positive regulation of auxin mediated signaling pathway	Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.	got7fsn_ti	positive regulation of auxin mediated signalling pathway													biological_process											owl:Class	
GO:0090298	biolink:NamedThing	negative regulation of mitochondrial DNA replication	Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.	got7fsn_ti	negative regulation of mitochondrial DNA synthesis						tb	2010-03-12T03:58:25Z						biological_process											owl:Class	
GO:0033171	biolink:NamedThing	obsolete nucleoprotein filament-forming ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of proteins such as Rad51p onto single-stranded (ss) DNA to form a helical nucleoprotein filament.	got7fsn_ti	nucleoprotein filament-forming ATPase activity				This term was made obsolete because nucleoprotein filament formation does not require ATP hydrolysis, so the term is misleading.					True				molecular_function											owl:Class	
GO:0032086	biolink:NamedThing	regulation of type III site-specific deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity.	got7fsn_ti	regulation of type III restriction endoribonuclease activity|type III restriction endodeoxyribonuclease regulator|type III restriction enzyme regulator													biological_process											owl:Class	
GO:0010141	biolink:NamedThing	obsolete guanine, xanthine and their nucleoside salvage	OBSOLETE. The pathway by which guanine, xanthine and their nucleoside from purine nucleotides breakdown are converted back to purine nucleotides. The pathway is important in cells where there is no de-novo purine nucleotides biosynthesis.	got7fsn_ti	guanine, xanthine and their nucleoside salvage				This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology.	GO:0006190|GO:0006178|GO:0043103|GO:0006179				True				biological_process											owl:Class	
GO:1904218	biolink:NamedThing	negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.	got7fsn_ti	downregulation of phosphatidylserine synthase activity|inhibition of CDP-diglyceride:serine phosphatidyltransferase activity|inhibition of CDP-diglycerine-serine O-phosphatidyltransferase activity|down regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|negative regulation of PS synthase activity|down regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|down-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|down regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|inhibition of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|negative regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|downregulation of phosphatidylserine synthetase activity|inhibition of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|inhibition of CDPdiglyceride-serine O-phosphatidyltransferase activity|down-regulation of phosphatidylserine synthetase activity|down regulation of phosphatidylserine synthase activity|down-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|inhibition of phosphatidylserine synthase activity|down regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|negative regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|negative regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|downregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|down-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|inhibition of phosphatidylserine synthetase activity|downregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|down-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|negative regulation of phosphatidylserine synthetase activity|down regulation of CDP-diglyceride:serine phosphatidyltransferase activity|down regulation of PS synthase activity|inhibition of PS synthase activity|downregulation of PS synthase activity|down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|negative regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|down regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|down-regulation of phosphatidylserine synthase activity|inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|down-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|inhibition of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|negative regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|down-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|inhibition of CDP-diglyceride-L-serine phosphatidyltransferase activity|inhibition of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|down regulation of phosphatidylserine synthetase activity|downregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|negative regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of PS synthase activity|down regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|downregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|down regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|negative regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|negative regulation of phosphatidylserine synthase activity|down regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|downregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|negative regulation of CDP-diglyceride:serine phosphatidyltransferase activity|downregulation of CDP-diglyceride:serine phosphatidyltransferase activity|inhibition of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of CDP-diglyceride:serine phosphatidyltransferase activity				Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate		rl	2015-05-15T08:18:29Z						biological_process											owl:Class	
GO:0071898	biolink:NamedThing	obsolete regulation of estrogen receptor binding	OBSOLETE. Any process that modulates the frequency, rate or extent of estrogen receptor binding, interacting selectively with a an estrogen receptor.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19354			This term was obsoleted because it represents a molecular function.		mah	2010-09-15T02:48:49Z		True				biological_process											owl:Class	
GO:1903117	biolink:NamedThing	regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of actin filament organization involved in cytokinetic actomyosin contractile ring assembly.	got7fsn_ti	regulation of regulation of actin filament localization of contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organization of contractile ring assembly|regulation of regulation of actin filament localization of constriction ring assembly|regulation of actin filament organization of cytokinesis, contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin contractile ring formation|regulation of actin filament organisation of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organisation of constriction ring assembly|regulation of actin filament organization of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organization of cytokinesis, actomyosin contractile ring formation|regulation of actin filament organization of cytokinesis, actomyosin ring formation|regulation of actin filament organisation of contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation|regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin ring formation|regulation of regulation of actin filament localization of cytokinesis, actomyosin ring formation|regulation of actin filament organization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organization of constriction ring assembly|regulation of actin filament organisation of cytokinesis, contractile ring assembly						al	2014-06-12T16:57:17Z						biological_process											owl:Class	
GO:1901050	biolink:NamedThing	atropine catabolic process	The chemical reactions and pathways resulting in the breakdown of atropine.	got7fsn_ti	atropine degradation|atropine breakdown|atropine catabolism						yaf	2012-06-28T04:51:51Z						biological_process											owl:Class	
GO:1900827	biolink:NamedThing	positive regulation of membrane depolarization during cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.	got7fsn_ti	up regulation of membrane depolarization during cardiac muscle cell action potential|upregulation of membrane depolarization during cardiac muscle cell action potential|up-regulation of membrane depolarization during cardiac muscle cell action potential|activation of membrane depolarization during cardiac muscle cell action potential						rl	2012-06-06T04:15:48Z						biological_process											owl:Class	
GO:0044661	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900763	biolink:NamedThing	averantin biosynthetic process	The chemical reactions and pathways resulting in the formation of averantin.	got7fsn_ti	averantin biosynthesis|averantin anabolism|averantin formation|averantin synthesis						di	2012-06-04T09:14:52Z						biological_process											owl:Class	
GO:0046506	biolink:NamedThing	sulfolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.	got7fsn_ti	sulpholipid biosynthesis|sulfolipid formation|sulfolipid anabolism|sulfolipid biosynthesis|sulpholipid biosynthetic process|sulfolipid synthesis													biological_process											owl:Class	
GO:0008357	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901744	biolink:NamedThing	2-deoxystreptamine biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine.	got7fsn_ti	2-deoxystreptamine formation|2-deoxystreptamine synthesis|2-deoxystreptamine anabolism|2-deoxystreptamine biosynthesis						yaf	2013-01-14T10:02:06Z						biological_process											owl:Class	
GO:1901359	biolink:NamedThing	tungstate binding	Binding to tungstate.	got7fsn_ti							crds	2012-09-14T08:33:56Z						molecular_function											owl:Class	
CHEBI:26174	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016585	biolink:NamedThing	obsolete chromatin remodeling complex	OBSOLETE. Any complex that mediates dynamic changes in eukaryotic chromatin.	got7fsn_ti	nucleosome remodeling complex|chromatin remodelling complex|chromatin remodeling complex				This term was made obsolete because its definition no longer reflects and cannot be modified to be consistent with the current state of knowledge.	GO:0006338				True	GO:0005679			cellular_component											owl:Class	
GO:0035816	biolink:NamedThing	renal water absorption involved in negative regulation of urine volume	Any process where water is taken up from the collecting ducts and proximal and distal loops of the nephron, which acts to decrease the amount of urine that is excreted from the body per unit time.	got7fsn_ti							bf	2011-04-20T01:37:34Z						biological_process											owl:Class	
GO:0046142	biolink:NamedThing	obsolete negative regulation of coenzyme and prosthetic group metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups.	got7fsn_ti	negative regulation of coenzyme and prosthetic group metabolic process				This term was made obsolete because it was replaced by more specific terms.	GO:0051201				True				biological_process											owl:Class	
GO:1901717	biolink:NamedThing	positive regulation of gamma-aminobutyric acid catabolic process	Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process.	got7fsn_ti	positive regulation of gamma-aminobutyric acid catabolism|up regulation of GABA catabolism|positive regulation of gamma-aminobutyric acid degradation|upregulation of GABA catabolism|up regulation of 4-aminobutanoate catabolic process|positive regulation of 4-aminobutanoate catabolism|up regulation of GABA catabolic process|upregulation of 4-aminobutanoate catabolism|activation of gamma-aminobutyric acid catabolic process|activation of GABA catabolism|activation of 4-aminobutanoate catabolic process|up regulation of gamma-aminobutyric acid catabolism|upregulation of gamma-aminobutyric acid degradation|activation of 4-aminobutyrate catabolism|upregulation of 4-aminobutyrate catabolic process|positive regulation of 4-aminobutyrate catabolism|up-regulation of gamma-aminobutyric acid catabolism|upregulation of gamma-aminobutyric acid catabolism|activation of gamma-aminobutyric acid catabolism|upregulation of GABA catabolic process|activation of gamma-aminobutyric acid breakdown|up-regulation of gamma-aminobutyric acid catabolic process|up-regulation of GABA catabolism|up-regulation of 4-aminobutanoate catabolic process|positive regulation of GABA catabolic process|upregulation of gamma-aminobutyric acid breakdown|up regulation of 4-aminobutyrate catabolic process|upregulation of gamma-aminobutyric acid catabolic process|up regulation of 4-aminobutanoate catabolism|up-regulation of GABA catabolic process|up-regulation of gamma-aminobutyric acid breakdown|activation of GABA catabolic process|positive regulation of 4-aminobutyrate catabolic process|up regulation of 4-aminobutyrate catabolism|positive regulation of 4-aminobutanoate catabolic process|up regulation of gamma-aminobutyric acid catabolic process|activation of gamma-aminobutyric acid degradation|up regulation of gamma-aminobutyric acid breakdown|upregulation of 4-aminobutyrate catabolism|positive regulation of gamma-aminobutyric acid breakdown|up-regulation of 4-aminobutyrate catabolism|activation of 4-aminobutyrate catabolic process|up-regulation of 4-aminobutyrate catabolic process|activation of 4-aminobutanoate catabolism|up-regulation of 4-aminobutanoate catabolism|up regulation of gamma-aminobutyric acid degradation|up-regulation of gamma-aminobutyric acid degradation|positive regulation of GABA catabolism|upregulation of 4-aminobutanoate catabolic process						mcc	2012-12-19T16:13:36Z						biological_process											owl:Class	
GO:0034436	biolink:NamedThing	glycoprotein transport	The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1900881	biolink:NamedThing	18-methylnonadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene.	got7fsn_ti	18-methylnonadec-1-ene biosynthesis|18-methylnonadec-1-ene formation|18-methylnonadec-1-ene synthesis|18-methylnonadec-1-ene anabolism						tt	2012-06-13T02:26:55Z						biological_process											owl:Class	
GO:0046359	biolink:NamedThing	butyrate catabolic process	The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid.	got7fsn_ti	butyrate catabolism|butanoic acid breakdown|butanoic acid degradation|butyrate breakdown|butanoic acid catabolic process|butanoic acid catabolism|butyrate degradation										GO:0043440			biological_process											owl:Class	
GO:1901704	biolink:NamedThing	L-glutamine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-glutamine.	got7fsn_ti	L-glutamine biosynthesis|L-glutamine formation|L-glutamine anabolism|L-glutamine synthesis						pde	2012-12-13T23:32:52Z						biological_process											owl:Class	
GO:1901851	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process	The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.	got7fsn_ti	coenzyme F0 breakdown|7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolism|coenzyme F0 catabolism|coenzyme F0 degradation|7,8-didemethyl-8-hydroxy-5-deazariboflavin breakdown|coenzyme F0 catabolic process|7,8-didemethyl-8-hydroxy-5-deazariboflavin degradation						yaf	2013-01-28T11:38:36Z						biological_process											owl:Class	
GO:1904739	biolink:NamedThing	regulation of synapse organization by posttranscriptional regulation of gene expression	A posttranscriptional regulation of gene expression that results in regulation of synapse organization.	got7fsn_ti	regulation of synapse development by posttranscriptional regulation of gene expression|regulation of synapse morphogenesis by posttranscriptional regulation of gene expression|regulation of synapse organization and biogenesis by posttranscriptional regulation of gene expression|regulation of synapse organisation by posttranscriptional regulation of gene expression						tb	2015-10-15T21:25:46Z						biological_process											owl:Class	
GO:0030470	biolink:NamedThing	obsolete spore germination (sensu Fungi)	OBSOLETE. Process of breakdown or opening of the spore-containing structure, modification of the spore wall, and resumption of growth of the spore. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).	got7fsn_ti	spore germination (sensu Fungi)|germination (sensu Saccharomyces)			GO:0009847	This term was made obsolete because a sensu term was not needed.					True	GO:0007153			biological_process											owl:Class	
GO:1904546	biolink:NamedThing	obsolete negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway	OBSOLETE. Any negative regulation of cAMP-dependent protein kinase activity that is involved in negative regulation of glucose mediated signaling pathway.	got7fsn_ti	negative regulation of PKA involved in down regulation of glucose mediated signalling|negative regulation of PKA C involved in inhibition of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in downregulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in down regulation of glucose mediated signalling|negative regulation of AMPK involved in inhibition of glucose mediated signaling pathway|negative regulation of STK22 involved in inhibition of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signalling|negative regulation of PKA C involved in down-regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of AMPK involved in negative regulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in downregulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down regulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down-regulation of glucose mediated signalling|negative regulation of STK22 involved in downregulation of glucose mediated signalling|negative regulation of PKA involved in down regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in inhibition of glucose mediated signalling|negative regulation of protein kinase A activity involved in downregulation of glucose mediated signaling pathway|negative regulation of PKA C involved in negative regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signalling|negative regulation of AMPK involved in negative regulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in downregulation of glucose mediated signalling|negative regulation of PKA C involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA involved in negative regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in negative regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of STK22 involved in down-regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of PKA involved in inhibition of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA involved in down-regulation of glucose mediated signalling|negative regulation of STK22 involved in downregulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in down regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of STK22 involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in inhibition of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of STK22 involved in negative regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of PKA C involved in inhibition of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA involved in downregulation of glucose mediated signaling pathway|negative regulation of AMPK involved in downregulation of glucose mediated signalling|negative regulation of PKA C involved in down regulation of glucose mediated signalling|negative regulation of PKA C involved in downregulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signaling pathway|negative regulation of AMPK involved in down-regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in down-regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signalling|negative regulation of AMPK involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of PKA involved in negative regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in inhibition of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in inhibition of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of AMPK involved in down regulation of glucose mediated signalling|negative regulation of PKA involved in downregulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of AMPK involved in inhibition of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-08-12T09:48:46Z		True				biological_process											owl:Class	
UBERON:0001291	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010132	biolink:NamedThing	dhurrin biosynthetic process	The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound.	got7fsn_ti	dhurrin anabolism|dhurrin biosynthesis|dhurrin synthesis|dhurrin formation											MetaCyc:PWY-861		biological_process											owl:Class	
GO:0051405	biolink:NamedThing	obsolete microbial collagenase activity	OBSOLETE. Catalysis of the digestion of native collagen in the triple helical region at Xaa-Gly bonds.	got7fsn_ti	nucleolysin|Clostridium histolyticum collagenase activity|Achromobacter iophagus collagenase|aspergillopeptidase C|kollaza|clostridiopeptidase II|collagenase 1 activity|soycollagestin|azocollase activity|collagen protease activity|matirx metalloproteinase-18|collagenase A activity|collagen peptidase activity|metallocollagenase activity|Clostridium histolyticum proteinase A|matrix metalloproteinase-1|microbial collagenase activity|metalloproteinase-1|clostridiopeptidase A activity|clostridiopeptidase I|collagenase I activity|matrix metalloproteinase-8|collagenase MMP-1			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0046058	biolink:NamedThing	cAMP metabolic process	The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	adenosine 3',5'-cyclophosphate metabolism|cAMP generating peptide activity|3',5' cAMP metabolism|cyclic AMP metabolism|3',5' cAMP metabolic process|cAMP metabolism|3',5'-cAMP metabolic process|cyclic AMP metabolic process|adenosine 3',5'-cyclophosphate metabolic process|3',5'-cAMP metabolism													biological_process											owl:Class	
GO:1901107	biolink:NamedThing	granaticin metabolic process	The chemical reactions and pathways involving granaticin.	got7fsn_ti	granaticin metabolism						yaf	2012-07-11T02:51:08Z						biological_process											owl:Class	
GO:1904938	biolink:NamedThing	planar cell polarity pathway involved in axon guidance	Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance.	got7fsn_ti	Wnt receptor signalling pathway, planar cell polarity pathway involved in axon guidance|non-canonical Wnt signaling pathway involved in axon pathfinding|Wnt-JNK signaling pathway involved in axon pathfinding|Wnt-PCP signaling pathway involved in axon chemotaxis|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon chemotaxis|planar cell polarity pathway involved in axon growth cone guidance|PCP pathway involved in axon pathfinding|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|PCP pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon growth cone guidance|Wnt signaling pathway, planar cell polarity pathway involved in axon pathfinding|PCP pathway involved in axon growth cone guidance|Wnt signaling pathway, planar cell polarity pathway involved in axon chemotaxis|planar cell polarity pathway involved in axon chemotaxis|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon guidance|Wnt-JNK signaling pathway involved in axon guidance|planar cell polarity pathway involved in axon pathfinding|PCP pathway involved in axon guidance|Wnt-PCP signaling pathway involved in axon growth cone guidance|non-canonical Wnt signaling pathway involved in axon guidance|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon guidance|Wnt-JNK signaling pathway involved in axon chemotaxis|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon pathfinding|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon pathfinding|Wnt-PCP signaling pathway involved in axon guidance|Wnt-PCP signaling pathway involved in axon pathfinding|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon pathfinding|non-canonical Wnt signaling pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon guidance|non-canonical Wnt signaling pathway involved in axon growth cone guidance|planar cell polarity pathway involved in axon guidance|Wnt-PCP signaling involved in axon guidance|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon growth cone guidance						bf	2016-02-02T14:46:26Z						biological_process											owl:Class	
GO:1901036	biolink:NamedThing	positive regulation of L-glutamine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell.	got7fsn_ti	up-regulation of L-glutamine import|up regulation of L-glutamine uptake|up regulation of L-glutamine import|upregulation of L-glutamine uptake|activation of L-glutamine import|activation of L-glutamine uptake|positive regulation of L-glutamine import|up-regulation of L-glutamine uptake|positive regulation of L-glutamine uptake|upregulation of L-glutamine import						al	2012-06-21T07:31:56Z						biological_process											owl:Class	
GO:0034635	biolink:NamedThing	glutathione transport	The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0001800	biolink:NamedThing	negative regulation of type IIb hypersensitivity	Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.	got7fsn_ti	inhibition of type IIb hypersensitivity|down-regulation of type IIb hypersensitivity|down regulation of type IIb hypersensitivity|downregulation of type IIb hypersensitivity													biological_process											owl:Class	
GO:1900957	biolink:NamedThing	negative regulation of 17-methylnonadec-1-ene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.	got7fsn_ti	inhibition of 17-methylnonadec-1-ene anabolism|downregulation of 17-methylnonadec-1-ene biosynthesis|down-regulation of 17-methylnonadec-1-ene biosynthesis|inhibition of 17-methylnonadec-1-ene biosynthetic process|down-regulation of 17-methylnonadec-1-ene formation|down-regulation of 17-methylnonadec-1-ene anabolism|down regulation of 17-methylnonadec-1-ene anabolism|downregulation of 17-methylnonadec-1-ene synthesis|downregulation of 17-methylnonadec-1-ene formation|down regulation of 17-methylnonadec-1-ene biosynthesis|down regulation of 17-methylnonadec-1-ene biosynthetic process|inhibition of 17-methylnonadec-1-ene synthesis|inhibition of 17-methylnonadec-1-ene formation|down-regulation of 17-methylnonadec-1-ene biosynthetic process|negative regulation of 17-methylnonadec-1-ene synthesis|downregulation of 17-methylnonadec-1-ene anabolism|negative regulation of 17-methylnonadec-1-ene formation|down regulation of 17-methylnonadec-1-ene formation|down-regulation of 17-methylnonadec-1-ene synthesis|negative regulation of 17-methylnonadec-1-ene biosynthesis|negative regulation of 17-methylnonadec-1-ene anabolism|inhibition of 17-methylnonadec-1-ene biosynthesis|downregulation of 17-methylnonadec-1-ene biosynthetic process|down regulation of 17-methylnonadec-1-ene synthesis						tt	2012-06-14T03:27:39Z						biological_process											owl:Class	
GO:0035982	biolink:NamedThing	obsolete age-dependent behavioral decline	OBSOLETE. A developmental process that arises as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory.	got7fsn_ti	age-related behavioral decline|age-dependent behavioural decline|behavioral aging			GO:0090647	This term was made obsolete because it describes a phenotype.		bf	2011-08-23T01:30:55Z		True				biological_process											owl:Class	
GO:1905959	biolink:NamedThing	positive regulation of cellular response to alcohol	Any process that activates or increases the frequency, rate or extent of cellular response to alcohol.	got7fsn_ti	upregulation of cellular response to alcohol|up regulation of cellular response to alcohol|activation of cellular response to alcohol|up-regulation of cellular response to alcohol						hbye	2017-02-22T12:03:16Z						biological_process											owl:Class	
GO:0089703	biolink:NamedThing	L-aspartate transmembrane export from vacuole	The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
GO:1904180	biolink:NamedThing	negative regulation of membrane depolarization	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization.	got7fsn_ti	down-regulation of membrane depolarization|inhibition of membrane depolarization|downregulation of membrane depolarization|down regulation of membrane depolarization						sl	2015-04-29T22:29:25Z						biological_process											owl:Class	
GO:0061494	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902376	biolink:NamedThing	obsolete protein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process	OBSOLETE. Any protein denaturation that is involved in proteasomal ubiquitin-dependent protein catabolic process.	got7fsn_ti	protein denaturation involved in proteasomal ubiquitin-dependent protein breakdown|protein denaturation involved in proteasomal pathway|protein denaturation involved in proteasomal processing|protein denaturation involved in proteasomal ubiquitin-dependent protein degradation|protein denaturation involved in proteasome pathway|protein denaturation involved in proteasomal ubiquitin-dependent protein catabolism				This term was made obsolete because it was poorly defined and the intended usage was unclear.		al	2013-08-30T09:29:14Z		True				biological_process											owl:Class	
CHEBI:18346	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902515	biolink:NamedThing	thioredoxin-disulfide reductase complex	A protein complex which is capable of thioredoxin-disulfide reductase activity.	got7fsn_ti					An example of this is thioredoxin reductase (TrxB) in E. coli [P0A9P4] in PMID:10947986.		bhm	2013-11-26T11:43:38Z						cellular_component											owl:Class	
GO:0002602	biolink:NamedThing	negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.	got7fsn_ti	down regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|downregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of polysaccharide antigen via MHC class II|down-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|negative regulation of polysaccharide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0009711	biolink:NamedThing	purine alkaloid biosynthetic process	The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.	got7fsn_ti	purine alkaloid biosynthesis|purine alkaloid synthesis|purine alkaloid anabolism|purine alkaloid formation													biological_process											owl:Class	
GO:1903635	biolink:NamedThing	positive regulation of leucine-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of leucine-tRNA ligase activity.	got7fsn_ti	positive regulation of leucine translase activity|up-regulation of leucine-tRNA synthetase activity|up regulation of leucine-tRNA ligase activity|activation of leucyl-tRNA synthetase activity|upregulation of leucyl-transfer RNA synthetase activity|positive regulation of leucyl-transfer ribonucleic acid synthetase activity|up-regulation of leucine-tRNA ligase activity|up-regulation of leucyl-transfer RNA synthetase activity|positive regulation of L-leucine:tRNALeu ligase (AMP-forming)|upregulation of leucyl-transfer ribonucleic acid synthetase activity|upregulation of L-leucine:tRNALeu ligase (AMP-forming)|positive regulation of leucyl-transfer ribonucleate synthetase activity|upregulation of leucine-tRNA ligase activity|activation of leucyl-transfer ribonucleate synthetase activity|up regulation of leucine-tRNA synthetase activity|activation of leucine translase activity|up regulation of leucyl-tRNA synthetase activity|activation of leucyl-transfer ribonucleic acid synthetase activity|up regulation of L-leucine:tRNALeu ligase (AMP-forming)|activation of leucyl-transfer RNA synthetase activity|upregulation of leucine-tRNA synthetase activity|up regulation of leucyl-transfer ribonucleic acid synthetase activity|up regulation of leucyl-transfer RNA synthetase activity|up-regulation of leucyl-transfer ribonucleic acid synthetase activity|up-regulation of leucine translase activity|upregulation of leucyl-tRNA synthetase activity|up-regulation of L-leucine:tRNALeu ligase (AMP-forming)|up regulation of leucyl-transfer ribonucleate synthetase activity|activation of L-leucine:tRNALeu ligase (AMP-forming)|activation of leucine-tRNA ligase activity|positive regulation of leucine-tRNA synthetase activity|up-regulation of leucyl-transfer ribonucleate synthetase activity|positive regulation of leucyl-tRNA synthetase activity|activation of leucine-tRNA synthetase activity|upregulation of leucyl-transfer ribonucleate synthetase activity|upregulation of leucine translase activity|positive regulation of leucyl-transfer RNA synthetase activity|up-regulation of leucyl-tRNA synthetase activity|up regulation of leucine translase activity						sl	2014-11-20T00:25:08Z						biological_process											owl:Class	
GO:1900761	biolink:NamedThing	averantin metabolic process	The chemical reactions and pathways involving averantin.	got7fsn_ti	averantin metabolism						di	2012-06-04T09:14:22Z						biological_process											owl:Class	
GO:1903514	biolink:NamedThing	release of sequestered calcium ion into cytosol by endoplasmic reticulum	The directed movement of calcium ion from endoplasmic reticulum to cytosol.	got7fsn_ti	calcium ion transport from endoplasmic reticulum to cytosol						rl	2014-10-02T11:30:34Z						biological_process											owl:Class	
GO:0046178	biolink:NamedThing	D-gluconate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.	got7fsn_ti	D-gluconate formation|D-gluconate anabolism|D-gluconate synthesis|D-gluconate biosynthesis													biological_process											owl:Class	
GO:0075062	biolink:NamedThing	obsolete regulation of invasive hypha growth	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont invasive hypha formation in host|regulation of symbiont invasive hypha formation within host	https://github.com/geneontology/go-ontology/issues/19013			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0016091	biolink:NamedThing	prenol biosynthetic process	The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.	got7fsn_ti	prenol synthesis|prenol anabolism|prenol biosynthesis|prenol formation													biological_process											owl:Class	
GO:0045665	biolink:NamedThing	negative regulation of neuron differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.	got7fsn_ti	downregulation of neuron differentiation|down-regulation of neuron differentiation|down regulation of neuron differentiation|inhibition of neuron differentiation													biological_process											owl:Class	
GO:1902239	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.	got7fsn_ti	inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator						pr	2013-06-19T14:00:39Z						biological_process											owl:Class	
GO:0075340	biolink:NamedThing	obsolete negative regulation of growth or development of symbiont during interaction with host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	got7fsn_ti	negative regulation of growth or development of symbiont during interaction with host				This term was made obsolete because it contained a conjunction (or).	GO:0044147				True				biological_process											owl:Class	
GO:1905831	biolink:NamedThing	negative regulation of spindle assembly	Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly.	got7fsn_ti	inhibition of spindle biosynthesis|down-regulation of spindle assembly|inhibition of spindle formation|down regulation of bipolar spindle formation|inhibition of bipolar spindle biosynthesis|downregulation of bipolar spindle formation|negative regulation of spindle biosynthesis|down-regulation of spindle formation|downregulation of spindle assembly|inhibition of bipolar spindle formation|down regulation of spindle biosynthesis|down regulation of spindle assembly|downregulation of spindle biosynthesis|negative regulation of spindle formation|downregulation of bipolar spindle biosynthesis|negative regulation of bipolar spindle biosynthesis|negative regulation of bipolar spindle formation|down-regulation of bipolar spindle formation|down regulation of spindle formation|inhibition of spindle assembly|down-regulation of bipolar spindle biosynthesis|down regulation of bipolar spindle biosynthesis|down-regulation of spindle biosynthesis|downregulation of spindle formation						hbye	2017-01-17T10:26:37Z						biological_process											owl:Class	
CL:0000723	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903288	biolink:NamedThing	positive regulation of potassium ion import across plasma membrane	Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane.	got7fsn_ti	upregulation of potassium ion uptake|activation of potassium ion import|up-regulation of potassium ion uptake|positive regulation of potassium ion import|up-regulation of potassium import|positive regulation of potassium import|up regulation of potassium ion uptake|upregulation of potassium import|up regulation of potassium import|activation of potassium ion uptake|up-regulation of potassium ion import|up regulation of potassium ion import|positive regulation of potassium ion uptake|upregulation of potassium ion import|activation of potassium import						rl	2014-08-11T14:26:32Z						biological_process											owl:Class	
GO:0071405	biolink:NamedThing	cellular response to methanol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.	got7fsn_ti							mah	2009-12-14T02:54:44Z						biological_process											owl:Class	
GO:1901174	biolink:NamedThing	phytoene biosynthetic process	The chemical reactions and pathways resulting in the formation of phytoene.	got7fsn_ti	phytoene anabolism|phytoene synthesis|phytoene biosynthesis|phytoene formation						yaf	2012-07-19T09:48:15Z						biological_process											owl:Class	
GO:0015525	biolink:NamedThing	obsolete carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:proton antiporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015547|GO:0015549|GO:0015548				True				molecular_function											owl:Class	
GO:1901634	biolink:NamedThing	positive regulation of synaptic vesicle membrane organization	Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization.	got7fsn_ti	up-regulation of synaptic vesicle membrane organization and biogenesis|upregulation of synaptic vesicle membrane organization|up regulation of synaptic vesicle membrane organization and biogenesis|up-regulation of synaptic vesicle membrane organization|up-regulation of synaptic vesicle membrane organisation|activation of synaptic vesicle membrane organisation|activation of SLMV biogenesis|activation of synaptic vesicle membrane organization and biogenesis|activation of synaptic vesicle membrane organization|up regulation of SLMV biogenesis|positive regulation of SLMV biogenesis|upregulation of SLMV biogenesis|up regulation of synaptic vesicle membrane organisation|upregulation of synaptic vesicle membrane organisation|up-regulation of SLMV biogenesis|up regulation of synaptic vesicle membrane organization|positive regulation of synaptic vesicle membrane organization and biogenesis|upregulation of synaptic vesicle membrane organization and biogenesis|positive regulation of synaptic vesicle membrane organisation						ans	2012-11-15T11:40:59Z						biological_process											owl:Class	
GO:1905688	biolink:NamedThing	negative regulation of diacylglycerol kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity.	got7fsn_ti	negative regulation of diglyceride kinase activity|downregulation of diacylglycerol:ATP kinase activity|down-regulation of diacylglycerol kinase activity|inhibition of arachidonoyl-specific diacylglycerol kinase activity|down regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|down regulation of ATP:diacylglycerol phosphotransferase activity|downregulation of diacylglycerol kinase activity|downregulation of 1,2-diacylglycerol kinase activity|downregulation of ATP:diacylglycerol phosphotransferase activity|downregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|down-regulation of CTP:diacylglycerol kinase activity|negative regulation of DGK activity|negative regulation of 1,2-diacylglycerol kinase (phosphorylating)|down-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|down regulation of diglyceride kinase activity|inhibition of DGK activity|downregulation of arachidonoyl-specific diacylglycerol kinase activity|down-regulation of ATP:diacylglycerol phosphotransferase activity|downregulation of sn-1,2-diacylglycerol kinase activity|negative regulation of CTP:diacylglycerol kinase activity|down regulation of diacylglycerol kinase activity|down-regulation of diacylglycerol:ATP kinase activity|negative regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|downregulation of diglyceride kinase activity|downregulation of 1,2-diacylglycerol kinase (phosphorylating)|inhibition of 1,2-diacylglycerol kinase activity|inhibition of sn-1,2-diacylglycerol kinase activity|negative regulation of arachidonoyl-specific diacylglycerol kinase activity|down regulation of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of CTP:diacylglycerol kinase activity|inhibition of ATP:diacylglycerol phosphotransferase activity|inhibition of diglyceride kinase activity|downregulation of DGK activity|down-regulation of 1,2-diacylglycerol kinase activity|down regulation of CTP:diacylglycerol kinase activity|negative regulation of ATP:diacylglycerol phosphotransferase activity|inhibition of diacylglycerol:ATP kinase activity|inhibition of DG kinase activity|down-regulation of diglyceride kinase activity|down-regulation of DGK activity|down-regulation of sn-1,2-diacylglycerol kinase activity|down regulation of sn-1,2-diacylglycerol kinase activity|downregulation of DG kinase activity|inhibition of 1,2-diacylglycerol kinase (phosphorylating)|down-regulation of 1,2-diacylglycerol kinase (phosphorylating)|down regulation of diacylglycerol:ATP kinase activity|inhibition of CTP:diacylglycerol kinase activity|down-regulation of arachidonoyl-specific diacylglycerol kinase activity|negative regulation of sn-1,2-diacylglycerol kinase activity|down regulation of 1,2-diacylglycerol kinase activity|down regulation of DG kinase activity|negative regulation of 1,2-diacylglycerol kinase activity|inhibition of diacylglycerol kinase activity|down-regulation of DG kinase activity|down regulation of DGK activity|negative regulation of diacylglycerol:ATP kinase activity|negative regulation of DG kinase activity|down regulation of arachidonoyl-specific diacylglycerol kinase activity|inhibition of ATP:1,2-diacylglycerol 3-phosphotransferase activity						bc	2016-11-14T12:26:18Z						biological_process											owl:Class	
GO:0045108	biolink:NamedThing	regulation of intermediate filament polymerization or depolymerization	Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases.	got7fsn_ti														biological_process											owl:Class	
GO:0030508	biolink:NamedThing	obsolete thiol-disulfide exchange intermediate activity	OBSOLETE. Functions as an exchange intermediate in thiol-disulfide exchange reactions.	got7fsn_ti	thiol-disulphide exchange intermediate activity|thiol-disulfide exchange intermediate activity|thioredoxin|glutaredoxin				This term was made obsolete because it represents a combination of gene product features and involvement in a biological process.	GO:0003756|GO:0015036				True				molecular_function											owl:Class	
GO:1901347	biolink:NamedThing	negative regulation of secondary cell wall biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis.	got7fsn_ti	negative regulation of cellulose and pectin-containing secondary cell wall biogenesis|downregulation of secondary cell wall anabolism|down-regulation of secondary cell wall synthesis|inhibition of secondary cell wall formation|down regulation of plant-type secondary cell wall biogenesis|down-regulation of plant-type secondary cell wall biogenesis|down-regulation of secondary cell wall biosynthetic process|downregulation of secondary cell wall synthesis|negative regulation of plant-type secondary cell wall biogenesis|down regulation of cellulose and pectin-containing secondary cell wall biogenesis|down regulation of secondary cell wall synthesis|inhibition of secondary cell wall synthesis|down-regulation of cellulose and pectin-containing secondary cell wall biogenesis|down-regulation of secondary cell wall biogenesis|inhibition of plant-type secondary cell wall biogenesis|down regulation of secondary cell wall biogenesis|down regulation of secondary cell wall formation|downregulation of secondary cell wall biosynthetic process|inhibition of secondary cell wall biogenesis|down regulation of secondary cell wall biosynthetic process|downregulation of plant-type secondary cell wall biogenesis|inhibition of secondary cell wall anabolism|negative regulation of secondary cell wall formation|downregulation of cellulose and pectin-containing secondary cell wall biogenesis|inhibition of cellulose and pectin-containing secondary cell wall biogenesis|negative regulation of secondary cell wall synthesis|down-regulation of secondary cell wall anabolism|down regulation of secondary cell wall anabolism|downregulation of secondary cell wall formation|negative regulation of secondary cell wall anabolism|downregulation of secondary cell wall biogenesis|down-regulation of secondary cell wall formation|negative regulation of secondary cell wall biosynthetic process|inhibition of secondary cell wall biosynthetic process						tb	2012-09-07T17:58:05Z						biological_process											owl:Class	
GO:0031113	biolink:NamedThing	regulation of microtubule polymerization	Any process that modulates the frequency, rate or extent of microtubule polymerization.	got7fsn_ti														biological_process											owl:Class	
GO:0060550	biolink:NamedThing	positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity	Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.	got7fsn_ti							dph	2009-04-13T02:12:33Z						biological_process											owl:Class	
GO:1905486	biolink:NamedThing	regulation of anterior/posterior axon guidance	Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance.	got7fsn_ti	regulation of anterior/posterior axon pathfinding|regulation of anterior-posterior axon guidance						hbye	2016-09-23T13:18:33Z						biological_process											owl:Class	
GO:1904833	biolink:NamedThing	positive regulation of removal of superoxide radicals	Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals.	got7fsn_ti	up-regulation of cellular detoxification of superoxide radicals|upregulation of removal of O2-|up regulation of removal of oxygen free radicals|activation of removal of oxygen free radicals|up regulation of cellular detoxification of superoxide radicals|up regulation of removal of superoxide radicals|activation of cellular detoxification of superoxide radicals|upregulation of removal of oxygen free radicals|up regulation of removal of O2-|upregulation of cellular detoxification of superoxide radicals|positive regulation of cellular detoxification of superoxide radicals|positive regulation of removal of O2-|up-regulation of removal of superoxide radicals|up-regulation of removal of oxygen free radicals|activation of removal of superoxide radicals|positive regulation of removal of oxygen free radicals|activation of removal of O2-|up-regulation of removal of O2-|upregulation of removal of superoxide radicals						rph	2015-11-24T15:30:26Z						biological_process											owl:Class	
GO:1990740	biolink:NamedThing	obsolete non-selective anion channel activity	OBSOLETE. Enables the non-selective, energy-independent passage of anions across a lipid bilayer down a concentration gradient.	got7fsn_ti	nonselective anion channel activity				This term was made obsolete because it was added in error.		pr	2015-05-11T13:25:35Z		True				molecular_function											owl:Class	
GO:0075182	biolink:NamedThing	obsolete negative regulation of symbiont transcription in response to host	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22014			This term was obsoleted because it represents a GO-CAM model.	GO:0045892				True				biological_process											owl:Class	
GO:0023047	biolink:NamedThing	obsolete signal initiation by chemical mediator	OBSOLETE. The process in which a chemical signal causes activation of a receptor.	got7fsn_ti	signal initiation by chemical mediator				This term was made obsolete because the meaning of the term is ambiguous.	GO:0038023|GO:0070887|GO:0007165		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0010964	biolink:NamedThing	regulation of heterochromatin assembly by small RNA	Any process that modulates the frequency, rate or extent of heterochromatin assembly by small RNA.	got7fsn_ti	regulation of chromatin silencing by small RNA|regulation of RNAi-mediated heterochromatin assembly	https://github.com/geneontology/go-ontology/issues/19112					tb	2009-05-20T11:25:42Z						biological_process											owl:Class	
GO:1900426	biolink:NamedThing	positive regulation of defense response to bacterium	Any process that activates or increases the frequency, rate or extent of defense response to bacterium.	got7fsn_ti	upregulation of defense response to bacterium|positive regulation of defence response to bacterium|activation of antibacterial peptide activity|up-regulation of defense response to bacterium|positive regulation of antibacterial peptide activity|upregulation of antibacterial peptide activity|up-regulation of defence response to bacterium|activation of defense response to bacterium|upregulation of defence response to bacterium|up regulation of antibacterial peptide activity|upregulation of defense response to bacteria|activation of resistance response to pathogenic bacterium|positive regulation of defence response to bacteria|activation of defence response to bacterium|up-regulation of antibacterial peptide activity|positive regulation of defense response to bacteria|activation of defense response to bacteria|activation of resistance response to pathogenic bacteria|up-regulation of defense response to bacteria|activation of defence response to bacteria|up regulation of defence response to bacteria|up regulation of defense response to bacteria|up-regulation of defence response to bacteria|up regulation of defence response to bacterium|upregulation of defence response to bacteria|positive regulation of defense response to bacterium, incompatible interaction|up regulation of defense response to bacterium						dhl	2012-04-24T10:13:13Z			GO:1902479			biological_process											owl:Class	
GO:0070055	biolink:NamedThing	obsolete mRNA endonucleolytic cleavage involved in unfolded protein response	OBSOLETE. The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response.	got7fsn_ti	HAC1-type intron splice site recognition and cleavage|XBP1 mRNA cleavage|HAC1 mRNA cleavage|IRE1-mediated XBP-1 mRNA cleavage|ERN1-mediated XBP-1 mRNA cleavage				The reason for obsoletion is that this process represents a single step (molecular function)  of the IRE1-mediated unfolded protein response (GO:0036498).	GO:0036498				True				biological_process											owl:Class	
GO:1904733	biolink:NamedThing	negative regulation of electron transfer activity	Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity.	got7fsn_ti	down regulation of electron transfer flavoprotein|negative regulation of electron carrier, chlorophyll electron transport system|down-regulation of rubredoxin|down-regulation of polyferredoxin|downregulation of electron carrier, chlorophyll electron transport system|inhibition of electron donor activity|down regulation of azurin|downregulation of small blue copper electron carrier|downregulation of electron donor activity|downregulation of electron transfer flavoprotein, group II|down regulation of high-potential iron-sulfur carrier|downregulation of polyferredoxin|inhibition of electron transporter activity|down-regulation of electron transfer flavoprotein|down regulation of 3Fe-4S/4Fe-4S electron transfer carrier|down-regulation of small blue copper electron carrier|down regulation of adrenodoxin-type ferredoxin|down-regulation of electron donor activity|down-regulation of mononuclear iron electron carrier|negative regulation of small blue copper electron carrier|down regulation of copper electron carrier|downregulation of chloroplast-type ferredoxin|down regulation of rubredoxin|down-regulation of azurin|down regulation of chloroplast-type ferredoxin|down-regulation of high-potential iron-sulfur carrier|down-regulation of monocluster bacterial-type ferredoxin|down-regulation of electron carrier activity|down-regulation of redox-active disulfide bond electron carrier|negative regulation of dicluster bacterial-type ferredoxin|down regulation of electron carrier activity|downregulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of electron carrier, chlorophyll electron transport system|down regulation of electron transporter activity|negative regulation of electron transfer flavoprotein|downregulation of azurin|negative regulation of electron transporter activity|inhibition of copper electron carrier|inhibition of dicluster bacterial-type ferredoxin|inhibition of azurin|negative regulation of monocluster bacterial-type ferredoxin|inhibition of 3Fe-4S/4Fe-4S electron transfer carrier|down regulation of iron-sulfur electron transfer carrier|down-regulation of amicyanin|down-regulation of iron-sulfur electron transfer carrier|inhibition of chloroplast-type ferredoxin|inhibition of electron carrier activity|downregulation of electron acceptor activity|inhibition of amicyanin|down regulation of 2Fe-2S electron transfer carrier|negative regulation of high-potential iron-sulfur carrier|down-regulation of dicluster bacterial-type ferredoxin|down-regulation of bacterial-type ferredoxin|inhibition of electron transfer flavoprotein|downregulation of electron carrier activity|down-regulation of chloroplast-type ferredoxin|down regulation of mononuclear iron electron carrier|down-regulation of electron carrier, chlorophyll electron transport system|downregulation of electron transfer flavoprotein|downregulation of 2Fe-2S electron transfer carrier|down-regulation of copper electron carrier|downregulation of bacterial-type ferredoxin|down regulation of amicyanin|negative regulation of 3Fe-4S/4Fe-4S electron transfer carrier|negative regulation of electron transfer flavoprotein, group I|inhibition of electron transfer flavoprotein, group I|downregulation of 3Fe-4S/4Fe-4S electron transfer carrier|negative regulation of bacterial-type ferredoxin|down-regulation of electron acceptor activity|negative regulation of iron-sulfur electron transfer carrier|downregulation of redox-active disulfide bond electron carrier|negative regulation of polyferredoxin|down regulation of electron transfer flavoprotein, group II|inhibition of electron acceptor activity|downregulation of dicluster bacterial-type ferredoxin|inhibition of electron transfer flavoprotein, group II|downregulation of high-potential iron-sulfur carrier|downregulation of amicyanin|down-regulation of 3Fe-4S/4Fe-4S electron transfer carrier|negative regulation of adrenodoxin-type ferredoxin|down-regulation of adrenodoxin-type ferredoxin|down regulation of dicluster bacterial-type ferredoxin|down regulation of electron donor activity|downregulation of electron transporter activity|downregulation of mononuclear iron electron carrier|downregulation of copper electron carrier|inhibition of adrenodoxin-type ferredoxin|inhibition of 2Fe-2S electron transfer carrier|down regulation of electron transfer flavoprotein, group I|inhibition of thioredoxin-like 2Fe-2S ferredoxin|negative regulation of rubredoxin|negative regulation of azurin|inhibition of small blue copper electron carrier|downregulation of rubredoxin|inhibition of bacterial-type ferredoxin|downregulation of iron-sulfur electron transfer carrier|inhibition of high-potential iron-sulfur carrier|inhibition of electron carrier, chlorophyll electron transport system|down regulation of small blue copper electron carrier|inhibition of iron-sulfur electron transfer carrier|downregulation of electron transfer flavoprotein, group I|negative regulation of electron acceptor activity|negative regulation of amicyanin|down regulation of electron acceptor activity|negative regulation of electron transfer flavoprotein, group II|inhibition of monocluster bacterial-type ferredoxin|down regulation of redox-active disulfide bond electron carrier|down-regulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of bacterial-type ferredoxin|negative regulation of redox-active disulfide bond electron carrier|inhibition of redox-active disulfide bond electron carrier|negative regulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of polyferredoxin|down regulation of thioredoxin-like 2Fe-2S ferredoxin|downregulation of monocluster bacterial-type ferredoxin|inhibition of rubredoxin|down-regulation of 2Fe-2S electron transfer carrier|negative regulation of electron donor activity|down-regulation of electron transfer flavoprotein, group I|negative regulation of mononuclear iron electron carrier|negative regulation of copper electron carrier|negative regulation of chloroplast-type ferredoxin|down regulation of monocluster bacterial-type ferredoxin|negative regulation of 2Fe-2S electron transfer carrier|down-regulation of electron transporter activity|inhibition of polyferredoxin|inhibition of mononuclear iron electron carrier|downregulation of adrenodoxin-type ferredoxin|down-regulation of electron transfer flavoprotein, group II						lb	2015-10-15T07:51:26Z						biological_process											owl:Class	
GO:1905254	biolink:NamedThing	obsolete positive regulation of epidermal growth factor receptor signaling pathway involved in heart process	OBSOLETE. Any positive regulation of epidermal growth factor receptor signaling pathway that is involved in heart process.	got7fsn_ti	activation of epidermal growth factor receptor signaling pathway involved in heart process|positive regulation of EGFR signaling pathway involved in heart process|stimulation of epidermal growth factor receptor signaling pathway involved in cardiac process|stimulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in heart process|positive regulation of EGFR signaling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in heart process|positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signaling pathway involved in heart process				This term was obsoleted at the TermGenie Gatekeeper stage.		bc	2016-06-10T09:21:18Z		True				biological_process											owl:Class	
GO:0009766	biolink:NamedThing	obsolete primary charge separation	OBSOLETE. In the photosynthetic reaction centers, primary charge separation is initiated by the excitation of a molecule followed by the transfer of an electron to an electron acceptor molecule following energy transfer from light harvesting complexes.	got7fsn_ti					This term was obsoleted because it represents a mechanism, and is outside the scope of GO.					True				biological_process											owl:Class	
GO:1903658	biolink:NamedThing	positive regulation of type IV pilus biogenesis	Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis.	got7fsn_ti	upregulation of type IV pilus biogenesis|activation of TFP biogenesis|up-regulation of type IV fimbria assembly|up-regulation of type IV pilus biosynthesis|up-regulation of type IV fimbriae biogenesis|up regulation of type IV fimbrial assembly|activation of type IV fimbrium biogenesis|activation of type IV fimbrium assembly|up-regulation of type IV fimbrial assembly|up regulation of type IV fimbriae assembly|up-regulation of type IV fimbria biogenesis|positive regulation of type IV fimbrial biogenesis|up-regulation of type IV fimbrium biogenesis|up regulation of type IV fimbrial biogenesis|upregulation of type IV fimbria assembly|up regulation of type IV fimbria assembly|activation of type IV fimbrial biogenesis|up regulation of type IV fimbria biogenesis|up regulation of TFP biogenesis|up-regulation of type IV fimbrium assembly|activation of type IV fimbria assembly|positive regulation of type IV fimbrial assembly|positive regulation of type IV pilus biosynthesis|positive regulation of type IV fimbriae assembly|upregulation of type 4 pilus biogenesis|up regulation of type IV fimbrium biogenesis|upregulation of type IV fimbria biogenesis|up-regulation of TFP biogenesis|upregulation of type IV fimbrium assembly|upregulation of type IV pilus biosynthesis|positive regulation of type IV fimbria assembly|activation of type IV fimbriae biogenesis|upregulation of type IV fimbriae assembly|positive regulation of type IV fimbriae biogenesis|up regulation of type IV fimbriae biogenesis|up regulation of type IV pilus biosynthesis|up-regulation of type 4 pilus biogenesis|up regulation of type 4 pilus biogenesis|up-regulation of type IV fimbrial biogenesis|upregulation of type IV fimbriae biogenesis|activation of type IV pilus biosynthesis|activation of type IV pilus biogenesis|positive regulation of type IV fimbria biogenesis|upregulation of type IV fimbrium biogenesis|activation of type 4 pilus biogenesis|positive regulation of type IV fimbrium assembly|upregulation of type IV fimbrial biogenesis|activation of type IV fimbria biogenesis|positive regulation of type IV fimbrium biogenesis|activation of type IV fimbriae assembly|upregulation of type IV fimbrial assembly|positive regulation of TFP biogenesis|up regulation of type IV pilus biogenesis|positive regulation of type 4 pilus biogenesis|up-regulation of type IV fimbriae assembly|up-regulation of type IV pilus biogenesis|activation of type IV fimbrial assembly|up regulation of type IV fimbrium assembly|upregulation of TFP biogenesis						jl	2014-11-25T12:03:34Z						biological_process											owl:Class	
GO:0071552	biolink:NamedThing	obsolete RIP homotypic interaction motif-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RIP homotypic interaction motif (RHIM) interaction.	got7fsn_ti	RHIM-mediated complex assembly				This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-13T03:08:30Z		True				biological_process											owl:Class	
GO:1905004	biolink:NamedThing	picolinic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of picolinic acid.	got7fsn_ti	picolinic acid anabolism|picolinate biosynthetic process|picolinate biosynthesis|picolinic acid biosynthesis|picolinic acid formation|picolinic acid synthesis						bf	2016-03-01T14:06:35Z						biological_process											owl:Class	
GO:0046076	biolink:NamedThing	dTTP catabolic process	The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.	got7fsn_ti	dTTP breakdown|dTTP degradation|dTTP catabolism													biological_process											owl:Class	
GO:1905472	biolink:NamedThing	negative regulation of histone H3-K79 dimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 dimethylation.	got7fsn_ti	negative regulation of histone H3 K79 dimethylation|down regulation of histone lysine H3 K79 dimethylation|inhibition of histone lysine H3 K79 dimethylation|negative regulation of histone lysine H3 K79 dimethylation|down-regulation of histone lysine H3 K79 dimethylation|downregulation of histone H3 K79 dimethylation|inhibition of histone H3 K79 dimethylation|down regulation of histone H3 K79 dimethylation|downregulation of histone lysine H3 K79 dimethylation|down regulation of histone H3-K79 dimethylation|down-regulation of histone H3 K79 dimethylation|down-regulation of histone H3-K79 dimethylation|inhibition of histone H3-K79 dimethylation|downregulation of histone H3-K79 dimethylation						hbye	2016-09-21T15:27:10Z						biological_process											owl:Class	
GO:1904940	biolink:NamedThing	negative regulation of DNA nucleotidylexotransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA nucleotidylexotransferase activity.	got7fsn_ti	down-regulation of terminal deoxyribonucleotidyltransferase activity|downregulation of addase activity|down-regulation of deoxynucleotidyl terminal transferase activity|downregulation of terminal addition enzyme activity|downregulation of DNA nucleotidylexotransferase activity|down-regulation of terminal deoxynucleotide transferase activity|downregulation of terminal transferase activity|down-regulation of DNA nucleotidylexotransferase activity|negative regulation of terminal transferase activity|downregulation of terminal deoxyribonucleotidyltransferase activity|inhibition of terminal addition enzyme activity|down regulation of terminal transferase activity|negative regulation of terminal deoxynucleotide transferase activity|down regulation of deoxyribonucleic acid nucleotidyltransferase activity|downregulation of TdT|inhibition of terminal deoxynucleotide transferase activity|down regulation of deoxyribonucleic nucleotidyltransferase activity|downregulation of deoxynucleotidyl terminal transferase activity|downregulation of terminal deoxynucleotidyltransferase activity|inhibition of terminal transferase activity|down regulation of deoxynucleotidyl terminal transferase activity|negative regulation of terminal deoxyribonucleotidyltransferase activity|down-regulation of terminal addition enzyme activity|negative regulation of deoxyribonucleic acid nucleotidyltransferase activity|inhibition of terminal deoxynucleotidyltransferase activity|inhibition of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down regulation of DNA nucleotidylexotransferase activity|inhibition of TdT|down-regulation of addase activity|downregulation of terminal deoxynucleotide transferase activity|down-regulation of deoxyribonucleic acid nucleotidyltransferase activity|inhibition of addase activity|negative regulation of addase activity|inhibition of deoxyribonucleic acid nucleotidyltransferase activity|inhibition of DNA nucleotidylexotransferase activity|negative regulation of deoxyribonucleic nucleotidyltransferase activity|inhibition of terminal deoxyribonucleotidyltransferase activity|negative regulation of deoxynucleotidyl terminal transferase activity|down-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|negative regulation of TdT|down-regulation of terminal deoxynucleotidyltransferase activity|down-regulation of deoxyribonucleic nucleotidyltransferase activity|negative regulation of terminal deoxynucleotidyltransferase activity|inhibition of deoxyribonucleic nucleotidyltransferase activity|inhibition of deoxynucleotidyl terminal transferase activity|down regulation of terminal deoxynucleotide transferase activity|down-regulation of TdT|down regulation of terminal deoxynucleotidyltransferase activity|down-regulation of terminal transferase activity|downregulation of deoxyribonucleic acid nucleotidyltransferase activity|downregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|downregulation of deoxyribonucleic nucleotidyltransferase activity|down regulation of TdT|down regulation of terminal addition enzyme activity|down regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down regulation of addase activity|down regulation of terminal deoxyribonucleotidyltransferase activity|negative regulation of terminal addition enzyme activity|negative regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity						bc	2016-02-02T15:16:05Z						biological_process											owl:Class	
GO:1905552	biolink:NamedThing	positive regulation of protein localization to endoplasmic reticulum	Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum.	got7fsn_ti	activation of protein localisation in endoplasmic reticulum|activation of protein localization in endoplasmic reticulum|positive regulation of protein localisation in endoplasmic reticulum|up regulation of protein localization to endoplasmic reticulum|upregulation of protein localization in endoplasmic reticulum|up-regulation of protein localisation in endoplasmic reticulum|up-regulation of protein localization in endoplasmic reticulum|up regulation of protein localization in ER|positive regulation of protein localization in endoplasmic reticulum|upregulation of protein localization to endoplasmic reticulum|up regulation of protein localisation in endoplasmic reticulum|up-regulation of protein localization to endoplasmic reticulum|activation of protein localization to endoplasmic reticulum|upregulation of protein localization in ER|upregulation of protein localisation in endoplasmic reticulum|up regulation of protein localization in endoplasmic reticulum|activation of protein localization in ER|up-regulation of protein localization in ER|positive regulation of protein localization in ER						rz	2016-10-12T11:37:16Z						biological_process											owl:Class	
GO:1900808	biolink:NamedThing	fumigaclavine C catabolic process	The chemical reactions and pathways resulting in the breakdown of fumigaclavine C.	got7fsn_ti	fumigaclavine C catabolism|fumigaclavine C breakdown|fumigaclavine C degradation						di	2012-06-04T09:59:55Z						biological_process											owl:Class	
GO:2000678	biolink:NamedThing	negative regulation of transcription regulatory region DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.	got7fsn_ti							yaf	2011-05-09T03:28:14Z						biological_process											owl:Class	
GO:1904563	biolink:NamedThing	phosphatidylinositol 5-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate.	got7fsn_ti	phosphatidylinositol 5-phosphate formation|phosphatidylinositol 5-phosphate anabolism|phosphatidylinositol 5-phosphate biosynthesis|phosphatidylinositol 5-phosphate synthesis						dph	2015-08-18T16:21:50Z						biological_process											owl:Class	
GO:1902146	biolink:NamedThing	positive regulation of response to cell cycle checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling.	got7fsn_ti	positive regulation of response to G2/M transition checkpoint signaling|upregulation of G2/M transition checkpoint effector process|upregulation of response to G1/S transition checkpoint signaling|activation of response to G1/S transition checkpoint signaling|up regulation of cell cycle checkpoint effector process|upregulation of response to cell cycle checkpoint signaling|upregulation of cell cycle checkpoint effector process|activation of G2/M transition checkpoint effector process|up regulation of response to signal involved in cell cycle checkpoint|upregulation of response to signal involved in cell cycle checkpoint|activation of cell cycle checkpoint effector process|positive regulation of response to signal involved in G2/M transition checkpoint|up regulation of response to G1/S transition checkpoint signaling|up-regulation of response to signal involved in G2/M transition checkpoint|up regulation of G1/S transition checkpoint effector process|up-regulation of G2/M transition checkpoint effector process|upregulation of response to signal involved in G1/S transition checkpoint|activation of response to signal involved in G2/M transition checkpoint|upregulation of response to G2/M transition checkpoint signaling|up regulation of response to signal involved in G1/S transition checkpoint|up-regulation of response to cell cycle checkpoint signaling|up regulation of response to cell cycle checkpoint signaling|positive regulation of response to G1/S transition checkpoint signaling|up regulation of response to G2/M transition checkpoint signaling|activation of response to signal involved in G1/S transition checkpoint|positive regulation of response to signal involved in cell cycle checkpoint|up-regulation of cell cycle checkpoint effector process|up-regulation of response to G2/M transition checkpoint signaling|positive regulation of response to signal involved in G1/S transition checkpoint|up regulation of G2/M transition checkpoint effector process|up-regulation of G1/S transition checkpoint effector process|positive regulation of G2/M transition checkpoint effector process|upregulation of response to signal involved in G2/M transition checkpoint|activation of G1/S transition checkpoint effector process|activation of response to G2/M transition checkpoint signaling|positive regulation of cell cycle checkpoint effector process|activation of response to signal involved in cell cycle checkpoint|up-regulation of response to signal involved in cell cycle checkpoint|up regulation of response to signal involved in G2/M transition checkpoint|activation of response to cell cycle checkpoint signaling|positive regulation of G1/S transition checkpoint effector process|upregulation of G1/S transition checkpoint effector process|up-regulation of response to signal involved in G1/S transition checkpoint|up-regulation of response to G1/S transition checkpoint signaling						jl	2013-05-21T15:43:45Z						biological_process											owl:Class	
GO:1900469	biolink:NamedThing	negative regulation of phosphatidylserine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process.	got7fsn_ti	downregulation of phosphatidylserine biosynthetic process|down-regulation of phosphatidylserine biosynthetic process|down-regulation of phosphatidylserine synthesis|inhibition of phosphatidylserine biosynthetic process|down regulation of phosphatidylserine formation|down regulation of phosphatidylserine biosynthetic process|negative regulation of phosphatidylserine biosynthesis|downregulation of phosphatidylserine anabolism|down regulation of phosphatidylserine anabolism|down regulation of phosphatidylserine synthesis|down-regulation of phosphatidylserine formation|down-regulation of phosphatidylserine biosynthesis|down-regulation of phosphatidylserine anabolism|negative regulation of phosphatidylserine synthesis|inhibition of phosphatidylserine formation|inhibition of phosphatidylserine anabolism|inhibition of phosphatidylserine biosynthesis|inhibition of phosphatidylserine synthesis|downregulation of phosphatidylserine synthesis|downregulation of phosphatidylserine formation|negative regulation of phosphatidylserine anabolism|down regulation of phosphatidylserine biosynthesis|downregulation of phosphatidylserine biosynthesis|negative regulation of phosphatidylserine formation						dgf	2012-05-01T08:01:11Z						biological_process											owl:Class	
GO:0006214	biolink:NamedThing	thymidine catabolic process	The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.	got7fsn_ti	thymidine catabolism|thymidine degradation|thymidine breakdown|deoxyribosylthymine catabolism|deoxyribosylthymine catabolic process										GO:0006215			biological_process											owl:Class	
GO:0060277	biolink:NamedThing	obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle	OBSOLETE. Any process that stop, prevents or decreases transcription as part of the G1 phase of the mitotic cell cycle.	got7fsn_ti	negative regulation of transcription involved in G1 phase of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter during G1 phase of mitotic cell cycle				This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0071930|GO:0000122				True				biological_process											owl:Class	
GO:1901478	biolink:NamedThing	aminotriazole transmembrane transporter activity	Enables the transfer of amitrole from one side of a membrane to the other.	got7fsn_ti	aminotriazole transporter activity						tb	2012-10-04T23:21:06Z			GO:0015241			molecular_function											owl:Class	
GO:0035331	biolink:NamedThing	negative regulation of hippo signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.	got7fsn_ti	negative regulation of hippo signaling pathway|negative regulation of hippo signalling cascade|negative regulation of hippo signaling cascade						bf	2010-02-26T10:54:19Z						biological_process											owl:Class	
GO:1901405	biolink:NamedThing	negative regulation of tetrapyrrole catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process.	got7fsn_ti	down regulation of tetrapyrrole catabolism|down regulation of tetrapyrrole catabolic process|down-regulation of tetrapyrrole degradation|down regulation of tetrapyrrole degradation|downregulation of tetrapyrrole degradation|down regulation of tetrapyrrole breakdown|down-regulation of tetrapyrrole catabolism|down-regulation of tetrapyrrole catabolic process|downregulation of tetrapyrrole catabolic process|negative regulation of tetrapyrrole breakdown|downregulation of tetrapyrrole breakdown|inhibition of tetrapyrrole degradation|negative regulation of tetrapyrrole degradation|down-regulation of tetrapyrrole breakdown|negative regulation of tetrapyrrole catabolism|inhibition of tetrapyrrole catabolic process|inhibition of tetrapyrrole breakdown|downregulation of tetrapyrrole catabolism|inhibition of tetrapyrrole catabolism						tt	2012-10-01T14:39:22Z						biological_process											owl:Class	
GO:1902168	biolink:NamedThing	response to catechin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.	got7fsn_ti							rjd	2013-05-22T17:35:35Z						biological_process											owl:Class	
GO:0045985	biolink:NamedThing	positive regulation of pyrimidine nucleobase metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.	got7fsn_ti	positive regulation of pyrimidine base metabolism|up-regulation of pyrimidine base metabolic process|positive regulation of pyrimidine base metabolic process|activation of pyrimidine base metabolic process|stimulation of pyrimidine base metabolic process|up regulation of pyrimidine base metabolic process|upregulation of pyrimidine base metabolic process													biological_process											owl:Class	
GO:1903278	biolink:NamedThing	positive regulation of sodium ion export across plasma membrane	Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane.	got7fsn_ti	up regulation of sodium ion export from cell|activation of sodium ion export|upregulation of sodium ion export|up regulation of sodium ion export|positive regulation of sodium ion export|activation of sodium export|up-regulation of sodium ion export from cell|upregulation of sodium export|positive regulation of sodium ion export from cell|up-regulation of sodium export|upregulation of sodium ion export from cell|up-regulation of sodium ion export|up regulation of sodium export|positive regulation of sodium export|activation of sodium ion export from cell						rl	2014-08-08T17:10:30Z			GO:1903275			biological_process											owl:Class	
GO:1901127	biolink:NamedThing	candicidin biosynthetic process	The chemical reactions and pathways resulting in the formation of candicidin.	got7fsn_ti	candicidin formation|candicidin anabolism|candicidin biosynthesis|candicidin synthesis						yaf	2012-07-11T03:17:02Z						biological_process											owl:Class	
GO:0001404	biolink:NamedThing	obsolete invasive growth	OBSOLETE. Growth of a pathogenic organism that results in penetration into cells or tissues of the host organism. This often (but not necessarily) includes a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue.	got7fsn_ti	tissue invasion|invasive growth				This term was made obsolete because more appropriate terms were created.	GO:0044409				True				biological_process											owl:Class	
GO:0014039	biolink:NamedThing	negative regulation of Schwann cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.	got7fsn_ti	down-regulation of Schwann cell differentiation|down regulation of Schwann cell differentiation|downregulation of Schwann cell differentiation|inhibition of Schwann cell differentiation													biological_process											owl:Class	
GO:0106112	biolink:NamedThing	negative regulation of mitotic cohesin ssDNA (lagging strand) loading	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.	got7fsn_ti							hjd	2018-04-18T14:41:50Z						biological_process											owl:Class	
GO:0050943	biolink:NamedThing	negative regulation of iridophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation.	got7fsn_ti	down regulation of iridophore differentiation|down-regulation of iridophore differentiation|inhibition of iridophore differentiation|downregulation of iridophore differentiation													biological_process											owl:Class	
GO:0019574	biolink:NamedThing	sucrose catabolic process via 3'-ketosucrose	The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose.	got7fsn_ti	sucrose breakdown, using glucoside 3-dehydrogenase|sucrose catabolic process to D-glucose|sucrose catabolism, using glucoside 3-dehydrogenase|sucrose catabolic process, using glucoside 3-dehydrogenase|sucrose degradation, using glucoside 3-dehydrogenase											MetaCyc:SUCROSEUTIL2-PWY		biological_process											owl:Class	
GO:0052419	biolink:NamedThing	obsolete metabolism by host of substance in symbiont	OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0010969	biolink:NamedThing	regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.	got7fsn_ti							tb	2009-05-20T11:54:57Z						biological_process											owl:Class	
GO:0090203	biolink:NamedThing	obsolete transcriptional activation by promoter-terminator looping	OBSOLETE. The formation and maintenance of DNA loops that juxtapose the promoter and terminator regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.	got7fsn_ti	transcriptional activation by memory gene loops	https://github.com/geneontology/go-ontology/issues/20204			This term was obsoleted because it was defined like a molecular function.	GO:0045893	tb	2009-12-18T11:58:32Z		True				biological_process											owl:Class	
GO:0110149	biolink:NamedThing	regulation of biomineralization	Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.	got7fsn_ti	regulation of biomineral formation|regulation of mineralisation|regulation of biomineralisation|regulation of mineralization						kmv	2019-06-10T18:06:59Z						biological_process											owl:Class	
GO:1903940	biolink:NamedThing	negative regulation of TORC2 signaling	Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling.	got7fsn_ti	down-regulation of TORC2 signal transduction|negative regulation of TORC2 signal transduction|down-regulation of TORC2 signaling|downregulation of TORC2 signaling|inhibition of TORC2 signaling|down regulation of TORC2 signal transduction|inhibition of TORC2 signal transduction|down regulation of TORC2 signaling|downregulation of TORC2 signal transduction						al	2015-02-16T18:28:50Z						biological_process											owl:Class	
GO:0007149	biolink:NamedThing	obsolete colony morphology	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	colony morphology				This term was made obsolete because it describes a phenotype rather than a biological goal.					True				biological_process											owl:Class	
GO:0045753	biolink:NamedThing	negative regulation of acetate catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.	got7fsn_ti	downregulation of acetate catabolic process|negative regulation of acetate degradation|negative regulation of acetate catabolism|down-regulation of acetate catabolic process|negative regulation of acetate breakdown|down regulation of acetate catabolic process|inhibition of acetate catabolic process													biological_process											owl:Class	
GO:1902220	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.	got7fsn_ti	up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress|activation of intrinsic apoptotic signaling pathway in response to osmotic stress|up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress						rl	2013-06-13T10:19:18Z						biological_process											owl:Class	
GO:1905190	biolink:NamedThing	negative regulation of metaphase/anaphase transition of meiosis II	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II.	got7fsn_ti	negative regulation of meiosis II metaphase/anaphase transition						vw	2016-05-10T16:46:57Z						biological_process											owl:Class	
GO:0005377	biolink:NamedThing	obsolete intracellular copper ion transporter	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	intracellular copper transporter|intracellular copper ion transporter				This term was made obsolete because it contains both component and function information.	GO:0005375|GO:0005622				True				molecular_function											owl:Class	
GO:1900961	biolink:NamedThing	positive regulation of 17-methylnonadec-1-ene metabolic process	Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.	got7fsn_ti	upregulation of 17-methylnonadec-1-ene metabolism|up-regulation of 17-methylnonadec-1-ene metabolism|upregulation of 17-methylnonadec-1-ene metabolic process|up-regulation of 17-methylnonadec-1-ene metabolic process|activation of 17-methylnonadec-1-ene metabolism|up regulation of 17-methylnonadec-1-ene metabolic process|up regulation of 17-methylnonadec-1-ene metabolism|positive regulation of 17-methylnonadec-1-ene metabolism|activation of 17-methylnonadec-1-ene metabolic process						tt	2012-06-14T03:29:59Z						biological_process											owl:Class	
CHEBI:24472	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034079	biolink:NamedThing	butanediol biosynthetic process	The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.	got7fsn_ti	butanediol formation|butanediol anabolism|butanediol biosynthesis|butylene glycol biosynthesis|butylene glycol biosynthetic process|butanediol synthesis											MetaCyc:P125-PWY		biological_process											owl:Class	
GO:0009800	biolink:NamedThing	cinnamic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.	got7fsn_ti	phenylpropenoic acid biosynthetic process|cinnamic acid synthesis|cinnamylic acid biosynthesis|cinnamic acid biosynthesis|phenylacrylic acid biosynthetic process|phenylpropenoic acid biosynthesis|cinnamylic acid biosynthetic process|phenylacrylic acid biosynthesis|cinnamic acid anabolism|cinnamic acid formation													biological_process											owl:Class	
GO:0045677	biolink:NamedThing	negative regulation of R7 cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation.	got7fsn_ti	down regulation of R7 differentiation|down-regulation of R7 differentiation|downregulation of R7 differentiation|negative regulation of R7 differentiation|inhibition of R7 differentiation													biological_process											owl:Class	
GO:1905309	biolink:NamedThing	positive regulation of cohesin loading	Any process that activates or increases the frequency, rate or extent of cohesin loading.	got7fsn_ti	positive regulation of cohesin association with chromatin|positive regulation of cohesin localization to chromatin						vw	2016-07-08T16:12:18Z						biological_process											owl:Class	
GO:1905761	biolink:NamedThing	SCF ubiquitin ligase complex binding	Binding to a SCF ubiquitin ligase complex.	got7fsn_ti	Skp1/Cul1/F-box protein complex binding|SCF complex substrate recognition subunit binding|CRL1 complex binding|cullin-RING ligase 1 binding|Cul1-RING ubiquitin ligase complex binding|CDL1 complex binding|SCF complex binding						dph	2016-12-14T15:08:12Z						molecular_function											owl:Class	
GO:2000884	biolink:NamedThing	glucomannan catabolic process	The chemical reactions and pathways resulting in the breakdown of a glucomannan.	got7fsn_ti	glucomannan catabolism						jl	2011-07-28T09:19:03Z						biological_process											owl:Class	
GO:0007003	biolink:NamedThing	obsolete telomere binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	telomere binding			GO:0042162	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:1904452	biolink:NamedThing	negative regulation of potassium:proton exchanging ATPase activity	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.	got7fsn_ti	inhibition of H,K-ATPase activity|down-regulation of H,K-ATPase activity|downregulation of gastric H(+)/K(+) ATPase activity|down-regulation of gastric H(+)/K(+) ATPase activity|downregulation of gastric H+/K+ ATPase|down-regulation of (K+ + H+)-ATPase activity|down regulation of H+/K+-ATPase activity|negative regulation of H+-K+-ATPase activity|negative regulation of gastric H+/K+ ATPase|negative regulation of hydrogen:potassium exchanging ATPase activity|down-regulation of H+-K+-ATPase activity|down regulation of gastric H+/K+ ATPase|down-regulation of H(+)/K(+)-ATPase activity|negative regulation of H(+)/K(+)-exchanging ATPase activity|down-regulation of hydrogen/potassium-exchanging ATPase activity|negative regulation of gastric H(+)/K(+) ATPase activity|downregulation of H+/K+-ATPase activity|inhibition of hydrogen/potassium-exchanging ATPase activity|down regulation of hydrogen/potassium-exchanging ATPase activity|negative regulation of H,K-ATPase activity|inhibition of gastric H(+)/K(+) ATPase activity|inhibition of H(+)/K(+)-ATPase activity|downregulation of hydrogen:potassium exchanging ATPase activity|negative regulation of H(+)/K(+)-ATPase activity|inhibition of H+-K+-ATPase activity|downregulation of ATP phosphohydrolase (H+/K+-exchanging)|negative regulation of H+/K+-ATPase activity|down regulation of hydrogen:potassium-exchanging ATPase activity|down regulation of H,K-ATPase activity|down-regulation of ATP phosphohydrolase (H+/K+-exchanging)|inhibition of ATP phosphohydrolase (H+/K+-exchanging)|downregulation of (K+ + H+)-ATPase activity|down regulation of gastric H(+)/K(+) ATPase activity|negative regulation of (K+ + H+)-ATPase activity|inhibition of (K+ + H+)-ATPase activity|down regulation of H(+)/K(+)-ATPase activity|down regulation of H+/K+-exchanging ATPase activity|inhibition of hydrogen:potassium exchanging ATPase activity|down-regulation of H(+)/K(+)-exchanging ATPase activity|negative regulation of hydrogen:potassium-exchanging ATPase activity|down-regulation of gastric H+/K+ ATPase|down regulation of (K+ + H+)-ATPase activity|downregulation of H,K-ATPase activity|downregulation of H+/K+-exchanging ATPase activity|inhibition of H+/K+-exchanging ATPase activity|negative regulation of hydrogen/potassium-exchanging ATPase activity|down-regulation of H+/K+-exchanging ATPase activity|down-regulation of hydrogen:potassium-exchanging ATPase activity|downregulation of hydrogen/potassium-exchanging ATPase activity|down regulation of ATP phosphohydrolase (H+/K+-exchanging)|inhibition of gastric H+/K+ ATPase|downregulation of H(+)/K(+)-ATPase activity|inhibition of H+/K+-ATPase activity|down regulation of H(+)/K(+)-exchanging ATPase activity|downregulation of H+-K+-ATPase activity|down regulation of hydrogen:potassium exchanging ATPase activity|down regulation of H+-K+-ATPase activity|downregulation of hydrogen:potassium-exchanging ATPase activity|inhibition of H(+)/K(+)-exchanging ATPase activity|downregulation of H(+)/K(+)-exchanging ATPase activity|down-regulation of hydrogen:potassium exchanging ATPase activity|inhibition of hydrogen:potassium-exchanging ATPase activity|negative regulation of H+/K+-exchanging ATPase activity|down-regulation of H+/K+-ATPase activity|negative regulation of ATP phosphohydrolase (H+/K+-exchanging)						sl	2015-07-08T23:00:09Z						biological_process											owl:Class	
GO:1902248	biolink:NamedThing	5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding	Binding to 5-O-phosphono-alpha-D-ribofuranosyl diphosphate.	got7fsn_ti	5-phosphoribose 1-diphosphate binding|phosphoribosylpyrophosphate binding						mah	2013-06-20T16:20:29Z						molecular_function											owl:Class	
GO:0070453	biolink:NamedThing	regulation of heme biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.	got7fsn_ti	regulation of heme biosynthesis|regulation of heme synthesis|regulation of haem biosynthesis|regulation of heme anabolism|regulation of haem biosynthetic process|regulation of heme formation													biological_process											owl:Class	
GO:1901179	biolink:NamedThing	spheroidene catabolic process	The chemical reactions and pathways resulting in the breakdown of spheroidene.	got7fsn_ti	spheroidene breakdown|spheroidene catabolism|spheroidene degradation						yaf	2012-07-19T09:49:14Z						biological_process											owl:Class	
GO:0051194	biolink:NamedThing	obsolete positive regulation of cofactor metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.	got7fsn_ti	upregulation of cofactor metabolic process|activation of cofactor metabolic process|stimulation of cofactor metabolic process|positive regulation of cofactor metabolism|up-regulation of cofactor metabolic process|up regulation of cofactor metabolic process				1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True				biological_process											owl:Class	
GO:1905884	biolink:NamedThing	negative regulation of triglyceride transport	Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport.	got7fsn_ti	downregulation of triglyceride transport|down-regulation of triacylglycerol transport|downregulation of triacylglycerol transport|down regulation of triacylglycerol transport|down regulation of triglyceride transport|inhibition of triglyceride transport|negative regulation of triacylglycerol transport|down-regulation of triglyceride transport|inhibition of triacylglycerol transport						rz	2017-01-31T11:32:39Z						biological_process											owl:Class	
GO:0014059	biolink:NamedThing	regulation of dopamine secretion	Any process that modulates the frequency, rate or extent of the regulated release of dopamine.	got7fsn_ti														biological_process											owl:Class	
GO:1904489	biolink:NamedThing	regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter	A negative regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process.	got7fsn_ti	regulation of ROS metabolic process by down-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by downregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down-regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down-regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by downregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by inhibition of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by downregulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by downregulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by inhibition of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by inhibition of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by inhibition of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by inhibition of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by negative regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by down regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolism by downregulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by down regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by inhibition of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by downregulation of global transcription from RNA polymerase II promoter						kmv	2015-07-17T18:12:06Z						biological_process											owl:Class	
GO:0052571	biolink:NamedThing	obsolete response to symbiont immune response	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	response to symbiont immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0120006	biolink:NamedThing	regulation of glutamatergic neuron differentiation	Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13107					krc	2017-03-01T16:10:27Z						biological_process											owl:Class	
GO:0003686	biolink:NamedThing	obsolete DNA repair enzyme	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DNA repair enzyme				This term was made obsolete because it includes a process term.	GO:0003684				True				molecular_function											owl:Class	
GO:0035969	biolink:NamedThing	obsolete positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of sterol import by positive regulation of transcription from Pol II promoter|positive regulation of sterol influx by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by activation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by activation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by activation of transcription from RNA polymerase II promoter|positive regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:1900718	biolink:NamedThing	positive regulation of violaceol II biosynthetic process	Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process.	got7fsn_ti	up regulation of violaceol II biosynthetic process|activation of violaceol II biosynthetic process|up-regulation of violaceol II anabolism|upregulation of violaceol II synthesis|positive regulation of violaceol II biosynthesis|activation of violaceol II synthesis|activation of violaceol II biosynthesis|upregulation of violaceol II biosynthesis|up-regulation of violaceol II formation|up-regulation of violaceol II biosynthesis|positive regulation of violaceol II anabolism|upregulation of violaceol II formation|activation of violaceol II anabolism|up regulation of violaceol II synthesis|activation of violaceol II formation|upregulation of violaceol II biosynthetic process|positive regulation of violaceol II formation|up regulation of violaceol II formation|upregulation of violaceol II anabolism|up-regulation of violaceol II synthesis|up regulation of violaceol II biosynthesis|up-regulation of violaceol II biosynthetic process|up regulation of violaceol II anabolism|positive regulation of violaceol II synthesis						di	2012-05-22T05:06:06Z						biological_process											owl:Class	
GO:0016850	biolink:NamedThing	obsolete other lyase activity	OBSOLETE. A grouping term for lyases that cannot be more accurately categorized.	got7fsn_ti	other lyase activity				This term was made obsolete because it was an unnecessary grouping term.	GO:0016829				True				molecular_function											owl:Class	
GO:0006510	biolink:NamedThing	obsolete ATP-dependent proteolysis	OBSOLETE. The hydrolysis of a peptide bond or bonds within a protein using energy from the hydrolysis of ATP.	got7fsn_ti	ATP-dependent peptidolysis|ATP-dependent proteolysis			GO:0004176	This term was made obsolete because it represents a molecular function.	GO:0016485|GO:0006508|GO:0051603				True				biological_process											owl:Class	
GO:0052383	biolink:NamedThing	obsolete induction by organism of symbiont innate immunity	OBSOLETE. The activation by an organism of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of symbiont innate immunity|induction by organism of symbiont innate immune response|activation by organism of symbiont innate immune response|induction by organism of symbiont innate immunity				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0023018	biolink:NamedThing	obsolete T cell activation of signal transmission via diffusible molecule	OBSOLETE. The process in which signal transmission via a diffusible molecule is initiated by a T cell.	got7fsn_ti	T cell activation of signal transmission via diffusible molecule				This term was made obsolete because the meaning of the term is ambiguous.			2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0018951	biolink:NamedThing	p-xylene metabolic process	The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	p-xylene metabolism|para-xylene metabolism|para-xylene metabolic process											UM-BBD_pathwayID:pxy		biological_process											owl:Class	
GO:0009183	biolink:NamedThing	purine deoxyribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside diphosphate anabolism|purine deoxyribonucleoside diphosphate synthesis|purine deoxyribonucleoside diphosphate biosynthesis|purine deoxyribonucleoside diphosphate formation													biological_process											owl:Class	
GO:1904777	biolink:NamedThing	negative regulation of protein localization to cell cortex	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.	got7fsn_ti	inhibition of protein localization to cell cortex|down regulation of protein localisation to cell cortex|down regulation of protein localization to cell cortex|negative regulation of protein localisation to cell cortex|downregulation of protein localization to cell cortex|down-regulation of protein localization to cell cortex|inhibition of protein localisation to cell cortex|downregulation of protein localisation to cell cortex|down-regulation of protein localisation to cell cortex				An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.		es	2015-10-29T16:55:08Z						biological_process											owl:Class	
GO:1905291	biolink:NamedThing	positive regulation of CAMKK-AMPK signaling cascade	Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade.	got7fsn_ti	upregulation of stress-activated AMP-activated protein kinase signaling cascade|upregulation of CAMKK-AMPK signaling cascade|up regulation of stress-activated AMP-activated protein kinase signaling cascade|activation of CAMKK-AMPK signaling cascade|up-regulation of stress-activated AMP-activated protein kinase signaling cascade|positive regulation of stress-activated AMP-activated protein kinase signaling cascade|up regulation of CAMKK-AMPK signaling cascade|up-regulation of CAMKK-AMPK signaling cascade|activation of stress-activated AMP-activated protein kinase signaling cascade						sl	2016-06-23T20:37:10Z						biological_process											owl:Class	
GO:1900618	biolink:NamedThing	regulation of shoot system morphogenesis	Any process that modulates the frequency, rate or extent of shoot morphogenesis.	got7fsn_ti	regulation of shoot morphogenesis						tb	2012-05-15T09:24:37Z						biological_process											owl:Class	
GO:1902097	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium	Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium.	got7fsn_ti	upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacteria|activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity|upregulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacterium|stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|activation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacterium|positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacteria|activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|upregulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacteria|positive regulation of global transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up-regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacteria						kmv	2013-04-30T16:54:30Z						biological_process											owl:Class	
GO:1902126	biolink:NamedThing	(+)-pinoresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-pinoresinol.	got7fsn_ti	(+)-pinoresinol anabolism|(+)-pinoresinol biosynthesis|(+)-pinoresinol formation|(+)-pinoresinol synthesis						ms	2013-05-21T08:49:28Z						biological_process											owl:Class	
GO:0023043	biolink:NamedThing	obsolete signaling via lipid mediator	OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a lipid mediator.	got7fsn_ti	signaling via lipid mediator|signalling via lipid mediator				This term was made obsolete because the meaning of the term is ambiguous.	GO:0014065|GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0046620	biolink:NamedThing	regulation of organ growth	Any process that modulates the frequency, rate or extent of growth of an organ of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0035927	biolink:NamedThing	RNA import into mitochondrion	The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti	cytoplasmic RNA import into mitochondrion|nuclear-encoded RNA import into mitochondrion						bf	2011-07-19T09:39:37Z						biological_process											owl:Class	
GO:1903919	biolink:NamedThing	negative regulation of actin filament severing	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing.	got7fsn_ti	downregulation of barbed-end actin capping/severing activity|down-regulation of F-actin severing|negative regulation of F-actin severing|downregulation of actin filament severing activity|inhibition of F-actin severing|down regulation of F-actin severing|down-regulation of barbed-end actin capping/severing activity|inhibition of barbed-end actin capping/severing activity|negative regulation of barbed-end actin capping/severing activity|downregulation of F-actin severing|down regulation of barbed-end actin capping/severing activity|down regulation of actin filament severing|down regulation of actin filament severing activity|down-regulation of actin filament severing|inhibition of actin filament severing activity|inhibition of actin filament severing|down-regulation of actin filament severing activity|negative regulation of actin filament severing activity|downregulation of actin filament severing						als	2015-02-10T11:01:31Z						biological_process											owl:Class	
GO:1903017	biolink:NamedThing	positive regulation of exo-alpha-sialidase activity	Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity.	got7fsn_ti	up regulation of exo-alpha-sialidase activity|up-regulation of alpha-neuraminidase activity|up-regulation of neuraminidase activity|up regulation of neuraminidase activity|positive regulation of N-acylneuraminate glycohydrolase activity|positive regulation of acetylneuraminidase activity|up-regulation of acetylneuraminidase activity|upregulation of neuraminidase activity|upregulation of sialidase activity|activation of acetylneuraminyl hydrolase activity|up regulation of acetylneuraminyl hydrolase activity|activation of sialidase activity|up-regulation of N-acylneuraminate glycohydrolase activity|positive regulation of neuraminidase activity|upregulation of N-acylneuraminate glycohydrolase activity|up-regulation of sialidase activity|up-regulation of exo-alpha-sialidase activity|positive regulation of alpha-neuraminidase activity|up regulation of alpha-neuraminidase activity|up regulation of N-acylneuraminate glycohydrolase activity|activation of alpha-neuraminidase activity|positive regulation of acetylneuraminyl hydrolase activity|positive regulation of sialidase activity|activation of N-acylneuraminate glycohydrolase activity|upregulation of acetylneuraminyl hydrolase activity|upregulation of acetylneuraminidase activity|up-regulation of acetylneuraminyl hydrolase activity|up regulation of acetylneuraminidase activity|upregulation of alpha-neuraminidase activity|up regulation of sialidase activity|upregulation of exo-alpha-sialidase activity|activation of neuraminidase activity|activation of exo-alpha-sialidase activity|activation of acetylneuraminidase activity				human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA)		rl	2014-05-14T18:15:23Z						biological_process											owl:Class	
GO:0002731	biolink:NamedThing	negative regulation of dendritic cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.	got7fsn_ti	downregulation of dendritic cell cytokine production|down-regulation of dendritic cell cytokine production|inhibition of dendritic cell cytokine production|down regulation of dendritic cell cytokine production													biological_process											owl:Class	
GO:0045428	biolink:NamedThing	regulation of nitric oxide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.	got7fsn_ti	regulation of nitric oxide synthesis|regulation of nitric oxide biosynthesis|regulation of nitric oxide formation|regulation of nitric oxide anabolism													biological_process											owl:Class	
GO:1905505	biolink:NamedThing	positive regulation of motile cilium assembly	Any process that activates or increases the frequency, rate or extent of motile cilium assembly.	got7fsn_ti	up regulation of nodal cilium formation|upregulation of motile primary cilia assembly|up regulation of motile primary cilium assembly|up-regulation of nodal cilium assembly|up-regulation of nodal cilium formation|activation of motile primary cilia formation|activation of motile primary cilia assembly|up-regulation of motile primary cilium formation|up-regulation of motile primary cilia formation|up regulation of nodal cilium assembly|upregulation of nodal cilium formation|activation of nodal cilium formation|positive regulation of motile primary cilia formation|up-regulation of motile primary cilium assembly|positive regulation of nodal cilium formation|up regulation of motile primary cilia assembly|up-regulation of motile primary cilia assembly|activation of nodal cilium assembly|activation of motile primary cilium formation|upregulation of motile primary cilia formation|upregulation of motile primary cilium assembly|upregulation of nodal cilium assembly|activation of motile primary cilium assembly|up regulation of motile primary cilium formation|upregulation of motile primary cilium formation|up regulation of motile primary cilia formation|positive regulation of nodal cilium assembly|positive regulation of motile primary cilium assembly|positive regulation of motile primary cilium formation|positive regulation of motile primary cilia assembly						krc	2016-09-27T18:28:03Z						biological_process											owl:Class	
GO:0100061	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by transcription factor catabolic process	OBSOLETE. Any transcription factor catabolic process process that negatively regulates SREBP signaling pathway.	got7fsn_ti					The reason for obsoletion is that this term should be represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1905272	biolink:NamedThing	negative regulation of proton-transporting ATP synthase activity, rotational mechanism	Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.	got7fsn_ti	down regulation of proton-transporting ATP synthase activity, rotational mechanism|downregulation of hydrogen ion transporting two-sector ATPase activity|inhibition of hydrogen ion translocating F-type ATPase activity|negative regulation of hydrogen ion translocating F-type ATPase activity|down-regulation of proton-transporting ATP synthase activity, rotational mechanism|downregulation of proton-transporting ATP synthase activity, rotational mechanism|inhibition of hydrogen ion transporting two-sector ATPase activity|inhibition of hydrogen ion transporting ATP synthase activity, rotational mechanism|down regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|inhibition of H+-transporting ATP synthase activity|down-regulation of H+-transporting ATP synthase activity|down regulation of hydrogen ion translocating F-type ATPase activity|downregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|down-regulation of hydrogen ion transporting two-sector ATPase activity|downregulation of hydrogen ion translocating F-type ATPase activity|down-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|negative regulation of H+-transporting ATP synthase activity|downregulation of H+-transporting ATP synthase activity|negative regulation of hydrogen ion transporting two-sector ATPase activity|down regulation of hydrogen ion transporting two-sector ATPase activity|down-regulation of hydrogen ion translocating F-type ATPase activity|negative regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|inhibition of proton-transporting ATP synthase activity, rotational mechanism|down regulation of H+-transporting ATP synthase activity						als	2016-06-16T12:09:57Z						biological_process											owl:Class	
GO:1905548	biolink:NamedThing	obsolete negative regulation of subtelomeric heterochromatin assembly	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of subtelomeric heterochromatin assembly.	got7fsn_ti	down regulation of telomeric heterochromatin formation|inhibition of telomeric heterochromatin formation|downregulation of telomeric heterochromatin formation|downregulation of telomeric heterochromatin assembly|inhibition of telomeric heterochromatin assembly|down-regulation of telomeric heterochromatin assembly|down-regulation of telomeric heterochromatin formation|negative regulation of telomeric heterochromatin assembly|negative regulation of telomeric heterochromatin formation|down regulation of telomeric heterochromatin assembly	https://github.com/geneontology/go-ontology/issues/22027|https://github.com/geneontology/go-ontology/issues/19188			This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.		nc	2016-10-12T11:18:23Z		True				biological_process											owl:Class	
GO:0032966	biolink:NamedThing	negative regulation of collagen biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	got7fsn_ti	negative regulation of collagen synthesis|negative regulation of collagen biosynthesis|negative regulation of collagen formation|negative regulation of collagen anabolism													biological_process											owl:Class	
GO:0102132	biolink:NamedThing	obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity	OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21876			This term was obsoleted because it represents a specific substrate, and is beyond the specificity of GO.	GO:0004316				True				molecular_function											owl:Class	
GO:1902849	biolink:NamedThing	positive regulation of neuronal signal transduction	Any process that activates or increases the frequency, rate or extent of neuronal signal transduction.	got7fsn_ti	up-regulation of neuronal signal transduction|up regulation of neuronal signal transduction|upregulation of neuronal signal transduction|activation of neuronal signal transduction						sjp	2014-04-02T10:11:24Z						biological_process											owl:Class	
GO:2000180	biolink:NamedThing	negative regulation of androgen biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process.	got7fsn_ti	negative regulation of androgen formation|negative regulation of androgen anabolism|negative regulation of androgen biosynthesis|negative regulation of androgen synthesis						dph	2010-10-13T12:43:17Z						biological_process											owl:Class	
GO:0003807	biolink:NamedThing	obsolete plasma kallikrein activity	OBSOLETE. Catalysis of the selective cleavage of Arg-Xaa and Lys-Xaa bonds, including Lys-Arg and Arg-Ser bonds in (human) kininogen to release bradykinin.	got7fsn_ti	padreatin|kallikrein I|onokrein P|kallikrein II|urokallikrein|depot-padutin|kininogenase|serum kallikrein activity|urinary kallikrein|callicrein|kallidinogenase|panceatic kallikrein|plasma kallikrein activity|kallikrein|dilminal D|padutin|kininogenin activity|glumorin			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1902203	biolink:NamedThing	negative regulation of hepatocyte growth factor receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.	got7fsn_ti	negative regulation of HGF receptor signalling pathway|down regulation of HGF receptor signalling pathway|down regulation of Met signaling pathway|down-regulation of hepatocyte growth factor receptor signaling pathway|negative regulation of Met signaling pathway|negative regulation of HGF receptor signaling pathway|down-regulation of Met signaling pathway|downregulation of HGF receptor signalling pathway|downregulation of Met signaling pathway|down regulation of hepatocyte growth factor receptor signaling pathway|downregulation of hepatocyte growth factor receptor signaling pathway|inhibition of HGF receptor signalling pathway|down regulation of HGF receptor signaling pathway|downregulation of HGF receptor signaling pathway|inhibition of hepatocyte growth factor receptor signaling pathway|inhibition of HGF receptor signaling pathway|down-regulation of HGF receptor signalling pathway|down-regulation of HGF receptor signaling pathway|inhibition of Met signaling pathway						lb	2013-06-10T13:20:51Z						biological_process											owl:Class	
GO:0030845	biolink:NamedThing	phospholipase C-inhibiting G protein-coupled receptor signaling pathway	A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG).	got7fsn_ti	phospholipase C-inhibiting G-protein coupled receptor signaling pathway|GPCR signaling pathway via inhibition of PLC|G-protein-coupled inhibitory pathway of phospholipase C|PLC-inhibiting GPCR signaling pathway|phospholipase C inhibition|inhibition of phospholipase C activity involved in G-protein coupled receptor signalling pathway|GPCR signaling pathway coupled to inhibition of phospholipase C activity				This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) inhibition.									biological_process											owl:Class	
GO:0035495	biolink:NamedThing	regulation of SNARE complex disassembly	Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	got7fsn_ti							bf	2010-04-26T02:56:53Z						biological_process											owl:Class	
GO:0002829	biolink:NamedThing	negative regulation of type 2 immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.	got7fsn_ti	down regulation of type 2 immune response|negative regulation of T-helper 2 type immune response|inhibition of type 2 immune response|negative regulation of Th2 immune response|downregulation of type 2 immune response|down-regulation of type 2 immune response													biological_process											owl:Class	
GO:2001103	biolink:NamedThing	maltohexaose transport	The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:21:40Z						biological_process											owl:Class	
GO:0072046	biolink:NamedThing	establishment of planar polarity involved in nephron morphogenesis	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.	got7fsn_ti	establishment of planar cell polarity involved in nephron morphogenesis						mah	2010-01-25T03:24:04Z						biological_process											owl:Class	
GO:1900199	biolink:NamedThing	positive regulation of protein export from nucleus during meiotic anaphase II	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II.	got7fsn_ti	positive regulation of protein export from nucleus involved in meiotic anaphase II						pr	2012-03-20T06:35:19Z						biological_process											owl:Class	
GO:0046004	biolink:NamedThing	positive regulation of syncytial blastoderm mitotic cell cycle	Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.	got7fsn_ti	stimulation of progression through syncytial blastoderm mitotic cell cycle|positive regulation of progression through syncytial blastoderm mitotic cell cycle|activation of progression through syncytial blastoderm mitotic cell cycle|upregulation of progression through syncytial blastoderm mitotic cell cycle|up-regulation of progression through syncytial blastoderm mitotic cell cycle|positive regulation of syncytial blastoderm cell cycle progression|up regulation of progression through syncytial blastoderm mitotic cell cycle													biological_process											owl:Class	
GO:0030814	biolink:NamedThing	obsolete regulation of cAMP metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	regulation of cAMP metabolism|regulation of 3',5' cAMP metabolism|regulation of 3',5'-cAMP metabolism|regulation of cyclic AMP metabolism|regulation of cyclic AMP metabolic process|regulation of adenosine 3',5'-cyclophosphate metabolism|regulation of adenosine 3',5'-cyclophosphate metabolic process|regulation of 3',5' cAMP metabolic process|regulation of 3',5'-cAMP metabolic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0046399	biolink:NamedThing	glucuronate biosynthetic process	The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid.	got7fsn_ti	glucuronate biosynthesis|glucuronate anabolism|glucuronate formation|glucuronate synthesis													biological_process											owl:Class	
GO:1904150	biolink:NamedThing	negative regulation of microglial cell mediated cytotoxicity	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity.	got7fsn_ti	inhibition of microglial cell mediated cytotoxicity|downregulation of microglial cell mediated cytotoxicity|down-regulation of microglial cell mediated cytotoxicity|down regulation of microglial cell mediated cytotoxicity						nc	2015-04-15T08:05:35Z						biological_process											owl:Class	
GO:0098946	biolink:NamedThing	intrinsic component of presynaptic endocytic zone membrane	The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to presynaptic acive zone membrane													cellular_component											owl:Class	
GO:0032873	biolink:NamedThing	negative regulation of stress-activated MAPK cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.	got7fsn_ti	downregulation of stress-activated MAPK cascade|negative regulation of p38 MAPK signaling|negative regulation of stress-activated MAPK signalling pathway|negative regulation of stress-activated MAPKKK cascade|negative regulation of stress-activated MAPKKK signaling pathway|inhibition of stress-activated MAPK cascade|down regulation of stress-activated MAPK cascade|negative regulation of p38 MAPK signalling|down-regulation of stress-activated MAPK cascade|negative regulation of stress-activated MAPKKK signalling pathway|negative regulation of stress-activated MAPK signaling pathway													biological_process											owl:Class	
GO:2000467	biolink:NamedThing	positive regulation of glycogen (starch) synthase activity	Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity.	got7fsn_ti	positive regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|positive regulation of UDP-glycogen synthase activity|positive regulation of UDPG-glycogen transglucosylase activity|positive regulation of UDPG-glycogen synthetase activity|positive regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|positive regulation of UDP-glucose-glycogen glucosyltransferase activity|positive regulation of glycogen (starch) synthetase activity|positive regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity						yaf	2011-03-07T04:13:41Z						biological_process											owl:Class	
GO:0002580	biolink:NamedThing	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.	got7fsn_ti	regulation of peptide or polysaccharide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:1905026	biolink:NamedThing	positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.	got7fsn_ti	up-regulation of membrane repolarization during ventricular cardiac muscle cell action potential|up regulation of regulation of ventricular cardiac muscle repolarization|up regulation of membrane repolarization during ventricular cardiac muscle cell action potential|upregulation of ventricular repolarization|upregulation of regulation of ventricular cardiac muscle repolarization|up-regulation of ventricular repolarization|upregulation of electrocardiogram T wave|up regulation of ventricular repolarization|up-regulation of regulation of ventricular cardiac muscle repolarization|positive regulation of regulation of ventricular cardiac muscle repolarization|activation of membrane repolarization during ventricular cardiac muscle cell action potential|positive regulation of electrocardiogram T wave|up-regulation of electrocardiogram T wave|upregulation of membrane repolarization during ventricular cardiac muscle cell action potential|activation of regulation of ventricular cardiac muscle repolarization|positive regulation of ventricular repolarization|activation of electrocardiogram T wave|activation of ventricular repolarization|up regulation of electrocardiogram T wave						rph	2016-03-04T11:19:21Z						biological_process											owl:Class	
GO:0009390	biolink:NamedThing	dimethyl sulfoxide reductase complex	An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide.	got7fsn_ti	dimethyl sulphoxide reductase complex													cellular_component											owl:Class	
GO:0060211	biolink:NamedThing	regulation of nuclear-transcribed mRNA poly(A) tail shortening	Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.	got7fsn_ti	regulation of nuclear mRNA poly(A) tail shortening|regulation of 3' to 5' mRNA deadenylation|regulation of mRNA deadenylation													biological_process											owl:Class	
GO:1905155	biolink:NamedThing	positive regulation of membrane invagination	Any process that activates or increases the frequency, rate or extent of membrane invagination.	got7fsn_ti	up-regulation of membrane invagination|upregulation of membrane invagination|up regulation of membrane invagination|activation of membrane invagination						bf	2016-04-18T15:44:12Z						biological_process											owl:Class	
GO:1902983	biolink:NamedThing	DNA strand elongation involved in mitotic DNA replication	Any DNA strand elongation involved in mitotic cell cycle DNA replication.	got7fsn_ti	DNA strand elongation involved in mitotic cell cycle DNA replication						jl	2014-05-06T20:33:22Z						biological_process											owl:Class	
GO:1904172	biolink:NamedThing	positive regulation of bleb assembly	Any process that activates or increases the frequency, rate or extent of bleb assembly.	got7fsn_ti	upregulation of bleb assembly|activation of bleb assembly|activation of cell blebbing|up regulation of cell blebbing|upregulation of cell blebbing|up-regulation of bleb assembly|up-regulation of cell blebbing|up regulation of bleb assembly|positive regulation of cell blebbing						als	2015-04-23T09:32:31Z						biological_process											owl:Class	
GO:1903498	biolink:NamedThing	bundle sheath cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell.	got7fsn_ti							tb	2014-09-26T01:31:04Z						biological_process											owl:Class	
GO:2001287	biolink:NamedThing	negative regulation of caveolin-mediated endocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis.	got7fsn_ti	negative regulation of caveolae-mediated endocytosis|negative regulation of caveolin-dependent endocytosis|negative regulation of caveolae-dependent endocytosis						yaf	2011-12-15T04:13:27Z						biological_process											owl:Class	
GO:0075036	biolink:NamedThing	regulation of appressorium maturation	Any process that modulates the frequency, rate or extent of symbiont appressorium maturation.	got7fsn_ti	regulation of appressorium maturation on or near host|regulation of maturation of appressorium on or near host													biological_process											owl:Class	
GO:0030067	biolink:NamedThing	obsolete respiratory chain cytochrome b6	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	respiratory chain cytochrome b6				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:1902878	biolink:NamedThing	obsolete regulation of BMP signaling pathway involved in spinal cord association neuron specification	OBSOLETE. Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.	got7fsn_ti	regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|regulation of BMP signalling pathway involved in spinal cord association neuron specification|regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification				The reason for obsoletion is that this term represents a GO-CAM model.		mr	2014-04-03T15:25:32Z		True				biological_process											owl:Class	
GO:1903611	biolink:NamedThing	negative regulation of calcium-dependent ATPase activity	Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity.	got7fsn_ti	downregulation of calcium-dependent ATPase activity|inhibition of calcium-dependent ATPase activity|down-regulation of calcium-dependent ATPase activity|down regulation of calcium-dependent ATPase activity						sl	2014-11-18T00:42:57Z						biological_process											owl:Class	
GO:0006838	biolink:NamedThing	obsolete allantoin/allantoate transport	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	allantoin/allantoate transport				This term was made obsolete because it is a composite term that represents two individual processes.	GO:0015720|GO:0015719				True				biological_process											owl:Class	
GO:0050849	biolink:NamedThing	negative regulation of calcium-mediated signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.	got7fsn_ti	down-regulation of calcium-mediated signaling|negative regulation of calcium-mediated signalling|inhibition of calcium-mediated signaling|downregulation of calcium-mediated signaling|down regulation of calcium-mediated signaling													biological_process											owl:Class	
GO:0039536	biolink:NamedThing	negative regulation of RIG-I signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.	got7fsn_ti	negative regulation of RIG-I signalling pathway|negative regulation of DDX58 signaling pathway|negative regulation of retinoic acid inducible gene I signaling pathway						bf	2012-01-03T11:27:51Z						biological_process											owl:Class	
GO:1905063	biolink:NamedThing	regulation of vascular associated smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation.	got7fsn_ti	regulation of vascular smooth muscle cell differentiation|regulation of VSMC differentiation						rph	2016-03-21T11:14:53Z						biological_process											owl:Class	
GO:0071387	biolink:NamedThing	cellular response to cortisol stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.	got7fsn_ti	cellular response to hydrocortisone stimulus						mah	2009-12-11T03:57:55Z						biological_process											owl:Class	
GO:0090361	biolink:NamedThing	regulation of platelet-derived growth factor production	Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti							tb	2010-07-12T10:32:27Z						biological_process											owl:Class	
GO:0035954	biolink:NamedThing	obsolete positive regulation of dipeptide transport by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of dipeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of dipeptide transport by up regulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by activation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by stimulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by up-regulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by positive regulation of transcription from Pol II promoter|positive regulation of dipeptide transport by upregulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0033390	biolink:NamedThing	putrescine biosynthetic process from arginine via N-carbamoylputrescine	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps.	got7fsn_ti	putrescine biosynthesis from arginine via N-carbamoylputrescine|putrescine formation from arginine via N-carbamoylputrescine|putrescine anabolism from arginine via N-carbamoylputrescine|putrescine synthesis from arginine via N-carbamoylputrescine													biological_process											owl:Class	
GO:0031656	biolink:NamedThing	positive regulation of heat dissipation	Any process that activates or increases the rate or extent of heat dissipation.	got7fsn_ti	up-regulation of heat dissipation|activation of heat dissipation|upregulation of heat dissipation|stimulation of heat dissipation|up regulation of heat dissipation													biological_process											owl:Class	
GO:0097365	biolink:NamedThing	stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell.	got7fsn_ti							pr	2012-07-26T02:39:10Z						molecular_function											owl:Class	
GO:1990445	biolink:NamedThing	obsolete Multiciliate cell differentiation	OBSOLETE. The process in which a relatively unspecialized cell acquires features of a multiciliated cell, a specialized epithelial cell type that extends anywhere from 150 to 200 motile cilia per cell in order to produce a vigorous fluid flow critical to human health in several organ systems.	got7fsn_ti	Multiciliate cell differentiation				This term was obsoleted at the TermGenie Gatekeeper stage.		sp	2014-08-05T14:31:28Z		True				biological_process											owl:Class	
CHEBI:28427	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905322	biolink:NamedThing	positive regulation of mesenchymal stem cell migration	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration.	got7fsn_ti	upregulation of mesenchymal stem cell migration|activation of mesenchymal stem cell migration|up regulation of mesenchymal stem cell migration|up-regulation of mesenchymal stem cell migration						sl	2016-07-15T22:19:29Z						biological_process											owl:Class	
GO:2001128	biolink:NamedThing	methane biosynthetic process from methylamine	The chemical reactions and pathways resulting in the formation of a methane from a methylamine.	got7fsn_ti							jl	2011-10-13T10:23:25Z						biological_process											owl:Class	
GO:1904629	biolink:NamedThing	response to diterpene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.	got7fsn_ti							sl	2015-08-28T13:52:37Z						biological_process											owl:Class	
GO:0050992	biolink:NamedThing	dimethylallyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.	got7fsn_ti	dimethylallyl pyrophosphate biosynthetic process|dimethylallyl diphosphate synthesis|DPP biosynthesis|dimethylallyl diphosphate formation|DPP biosynthetic process|dimethylallyl pyrophosphate biosynthesis|dimethylallyl diphosphate biosynthesis|dimethylallyl diphosphate anabolism													biological_process											owl:Class	
GO:1901208	biolink:NamedThing	negative regulation of heart looping	Any process that stops, prevents or reduces the frequency, rate or extent of heart looping.	got7fsn_ti	negative regulation of cardiac looping|down-regulation of cardiac looping|downregulation of cardiac looping|down regulation of cardiac looping|inhibition of heart looping|down regulation of heart looping|downregulation of heart looping|inhibition of cardiac looping|down-regulation of heart looping						rl	2012-07-31T07:16:10Z						biological_process											owl:Class	
GO:1900885	biolink:NamedThing	negative regulation of tridecane biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process.	got7fsn_ti	down-regulation of tridecane synthesis|down regulation of tridecane formation|down regulation of tridecane anabolism|negative regulation of tridecane formation|negative regulation of tridecane anabolism|downregulation of tridecane formation|down regulation of tridecane biosynthesis|down-regulation of tridecane formation|negative regulation of tridecane synthesis|down-regulation of tridecane biosynthetic process|downregulation of tridecane biosynthetic process|inhibition of tridecane biosynthetic process|down-regulation of tridecane anabolism|down regulation of tridecane biosynthetic process|inhibition of tridecane anabolism|inhibition of tridecane synthesis|downregulation of tridecane synthesis|down regulation of tridecane synthesis|inhibition of tridecane formation|downregulation of tridecane anabolism|negative regulation of tridecane biosynthesis|inhibition of tridecane biosynthesis|downregulation of tridecane biosynthesis|down-regulation of tridecane biosynthesis						tt	2012-06-13T03:00:53Z						biological_process											owl:Class	
GO:1900459	biolink:NamedThing	positive regulation of brassinosteroid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway.	got7fsn_ti	up regulation of brassinosteroid mediated signaling pathway|upregulation of brassinosteroid mediated signalling|activation of brassinosteroid mediated signalling|up regulation of brassinosteroid mediated signalling|up-regulation of brassinosteroid mediated signalling|positive regulation of brassinosteroid mediated signalling|up-regulation of brassinosteroid mediated signaling pathway|activation of brassinosteroid mediated signaling pathway|upregulation of brassinosteroid mediated signaling pathway						dhl	2012-05-01T06:12:23Z						biological_process											owl:Class	
GO:1902378	biolink:NamedThing	VEGF-activated neuropilin signaling pathway involved in axon guidance	Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance.	got7fsn_ti	VEGF-activated neuropilin signaling pathway involved in axon growth cone guidance|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon pathfinding|VEGF-Npn-1 signaling involved in axon pathfinding|VEGF-Npn-1 signaling involved in axon guidance|VEGF-activated neuropilin signaling pathway involved in axon chemotaxis|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon growth cone guidance|VEGF-activated neuropilin signaling pathway involved in axon pathfinding|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon guidance|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon chemotaxis|VEGF-Npn-1 signaling involved in axon growth cone guidance|VEGF-Npn-1 signaling involved in axon chemotaxis						bf	2013-09-02T13:44:13Z						biological_process											owl:Class	
GO:0046705	biolink:NamedThing	CDP biosynthetic process	The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate.	got7fsn_ti	CDP anabolism|CDP biosynthesis|CDP synthesis|CDP formation													biological_process											owl:Class	
GO:0009969	biolink:NamedThing	xyloglucan biosynthetic process	The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.	got7fsn_ti	xyloglucan biosynthesis|xyloglucan formation|xyloglucan synthesis|xyloglucan anabolism													biological_process											owl:Class	
GO:1904205	biolink:NamedThing	negative regulation of skeletal muscle hypertrophy	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy.	got7fsn_ti	down regulation of skeletal muscle hypertrophy|down-regulation of skeletal muscle hypertrophy|downregulation of skeletal muscle hypertrophy|inhibition of skeletal muscle hypertrophy						sl	2015-05-08T17:38:19Z						biological_process											owl:Class	
GO:0072364	biolink:NamedThing	obsolete regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of cellular ketone metabolism by regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolic process by regulation of transcription from an RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:11:39Z		True				biological_process											owl:Class	
GO:0019583	biolink:NamedThing	galactonate metabolic process	The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose.	got7fsn_ti	galactonate metabolism													biological_process											owl:Class	
GO:0140407	biolink:NamedThing	L-alanine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-alanine(in) = H+(in) + L-alanine(out).	got7fsn_ti							pg	2019-12-11T14:17:48Z						molecular_function											owl:Class	
GO:0033697	biolink:NamedThing	obsolete positive regulation of extent of heterochromatin assembly	OBSOLETE. Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin.	got7fsn_ti	positive regulation of heterochromatin spreading|positive regulation of extent of heterochromatin formation	https://github.com/geneontology/go-ontology/issues/22028			This term has been obsoleted because there is no evidence it exists.	GO:0031507				True				biological_process											owl:Class	
GO:0019316	biolink:NamedThing	D-allose catabolic process	The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.	got7fsn_ti	D-allose catabolism|D-allose degradation|D-allose breakdown											MetaCyc:PWY0-44		biological_process											owl:Class	
GO:0033526	biolink:NamedThing	tetrapyrrole biosynthetic process from glutamate	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.	got7fsn_ti	tetrapyrrole biosynthesis from glutamate|tetrapyrrole synthesis from glutamate|tetrapyrrole anabolism from glutamate|tetrapyrrole formation from glutamate											MetaCyc:PWY-5188		biological_process											owl:Class	
GO:0061238	biolink:NamedThing	establishment of planar polarity involved in mesonephric nephron morphogenesis	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros.	got7fsn_ti	establishment of planar cell polarity involved in mesonephric nephron morphogenesis						dph	2010-08-19T03:04:40Z						biological_process											owl:Class	
GO:0023017	biolink:NamedThing	obsolete signal transmission via diffusible molecule	OBSOLETE. The process in which a signal is conveyed via a diffusible molecule.	got7fsn_ti	signaling via diffusible mediator|signal transmission via diffusible molecule				This term was made obsolete because the meaning of the term is ambiguous.	GO:0007267		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1902544	biolink:NamedThing	regulation of DNA N-glycosylase activity	Any process that modulates the frequency, rate or extent of DNA N-glycosylase activity.	got7fsn_ti	regulation of endonuclease VIII activity|regulation of DNA glycosylase activity						rph	2013-12-04T14:17:54Z						biological_process											owl:Class	
GO:1900644	biolink:NamedThing	negative regulation of chanoclavine-I biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I biosynthetic process.	got7fsn_ti	downregulation of chanoclavine-I synthesis|down-regulation of chanoclavine-I anabolism|down regulation of chanoclavine-I synthesis|negative regulation of chanoclavine-I formation|downregulation of chanoclavine-I biosynthetic process|inhibition of chanoclavine-I anabolism|inhibition of chanoclavine-I biosynthetic process|down-regulation of chanoclavine-I biosynthesis|inhibition of chanoclavine-I formation|down-regulation of chanoclavine-I synthesis|negative regulation of chanoclavine-I biosynthesis|inhibition of chanoclavine-I biosynthesis|down regulation of chanoclavine-I biosynthetic process|down regulation of chanoclavine-I biosynthesis|down regulation of chanoclavine-I anabolism|downregulation of chanoclavine-I anabolism|downregulation of chanoclavine-I biosynthesis|down regulation of chanoclavine-I formation|down-regulation of chanoclavine-I formation|negative regulation of chanoclavine-I synthesis|inhibition of chanoclavine-I synthesis|negative regulation of chanoclavine-I anabolism|downregulation of chanoclavine-I formation|down-regulation of chanoclavine-I biosynthetic process						di	2012-05-22T04:03:30Z						biological_process											owl:Class	
GO:0098943	biolink:NamedThing	neurotransmitter receptor transport, postsynaptic endosome to lysosome	The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation.	got7fsn_ti	postsynaptic neurotransmitter receptor endosomal trafficking													biological_process											owl:Class	
GO:1905581	biolink:NamedThing	positive regulation of low-density lipoprotein particle clearance	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance.	got7fsn_ti	upregulation of LDL clearance|up regulation of low-density lipoprotein particle clearance|positive regulation of LDL clearance|activation of low-density lipoprotein particle clearance|upregulation of low-density lipoprotein particle clearance|up-regulation of LDL clearance|up-regulation of low-density lipoprotein particle clearance|up regulation of LDL clearance|activation of LDL clearance						nc	2016-10-19T14:39:15Z						biological_process											owl:Class	
GO:0150105	biolink:NamedThing	protein localization to cell-cell junction	A process in which a protein is transported to, or maintained, in a location within a cell-cell junction.	got7fsn_ti							bc	2019-06-11T11:00:18Z						biological_process											owl:Class	
GO:1902503	biolink:NamedThing	adenylyltransferase complex	A protein complex which is capable of adenylyltransferase activity.	got7fsn_ti	ThiF-ThiS complex						bhm	2013-11-14T10:37:25Z						cellular_component											owl:Class	
GO:0120145	biolink:NamedThing	protein localization to basal ectoplasmic specialization	A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization.	got7fsn_ti	protein localisation in basal ectoplasmic specialization|protein localization in basal ectoplasmic specialization|protein localisation to basal ectoplasmic specialization						krc	2018-03-27T20:16:09Z						biological_process											owl:Class	
GO:1902320	biolink:NamedThing	nuclear DNA replication DNA duplex unwinding	Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication.	got7fsn_ti	duplex DNA melting involved in DNA replication during S phase|DNA unwinding involved in nuclear cell cycle DNA replication|duplex DNA melting involved in DNA replication involved in S phase|DNA duplex unwinding involved in DNA replication during S phase|DNA duplex unwinding involved in DNA replication involved in S-phase|DNA unwinding involved in DNA replication involved in S-phase|DNA duplex unwinding involved in DNA replication involved in S phase|DNA unwinding involved in DNA replication during S phase|DNA unwinding involved in DNA replication involved in S phase|DNA duplex unwinding involved in nuclear cell cycle DNA replication|duplex DNA melting involved in DNA replication involved in S-phase						jl	2013-07-23T14:00:49Z						biological_process											owl:Class	
GO:0034638	biolink:NamedThing	phosphatidylcholine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	got7fsn_ti	phosphatidylcholine degradation|phosphatidylcholine breakdown|phosphatidylcholine catabolism													biological_process											owl:Class	
GO:1905902	biolink:NamedThing	regulation of mesoderm formation	Any process that modulates the frequency, rate or extent of mesoderm formation.	got7fsn_ti							rph	2017-02-03T12:28:20Z						biological_process											owl:Class	
GO:2001196	biolink:NamedThing	positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.	got7fsn_ti	positive regulation of lysine biosynthetic process via aminoadipic acid and saccharopine|positive regulation of lysine biosynthesis via aminoadipic acid and saccharopine						mcc	2011-11-03T07:57:24Z						biological_process											owl:Class	
GO:2000708	biolink:NamedThing	myosin filament organization involved in cytokinetic actomyosin contractile ring assembly	A myosin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis.	got7fsn_ti	myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring formation|myosin filament assembly or disassembly of cytokinesis, contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring formation|myosin polymerization or depolymerization of cytokinesis, contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin ring formation|myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring assembly|myosin filament organization of cytokinesis, actomyosin contractile ring assembly|myosin filament assembly or disassembly of constriction ring assembly|myosin filament organization of cytokinesis, actomyosin ring biosynthesis|myosin filament assembly or disassembly of cytokinesis, actomyosin ring formation|myosin filament organization of cytokinesis, contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin ring biosynthesis|myosin filament organization of constriction ring assembly|myosin filament organization of contractile ring assembly|myosin polymerization or depolymerization of constriction ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin ring biosynthesis|myosin filament organization of cytokinesis, actomyosin contractile ring formation|myosin filament organization of cytokinesis, actomyosin ring formation|myosin polymerization or depolymerization of contractile ring assembly|myosin filament organisation involved in cytokinetic actomyosin contractile ring assembly|myosin filament assembly or disassembly of contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring assembly						mah	2011-06-01T12:33:56Z						biological_process											owl:Class	
GO:0004988	biolink:NamedThing	obsolete mu-opioid receptor activity	OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of mu-opioid receptors, including high affinity for enkephalins and beta-endorphin but low affinity for dynorphins.	got7fsn_ti	mu-opioid receptor activity				This term was made obsolete because the receptor is defined based on its pharmacological properties.	GO:0004979|GO:0038047|GO:0038046				True		Wikipedia:Mu_Opioid_receptor		molecular_function											owl:Class	
GO:1905042	biolink:NamedThing	negative regulation of epithelium regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration.	got7fsn_ti	downregulation of epithelium regeneration|down-regulation of regeneration of epithelium|negative regulation of regeneration of epithelium|down regulation of epithelium regeneration|inhibition of epithelium regeneration|down-regulation of epithelium regeneration|inhibition of regeneration of epithelium|downregulation of regeneration of epithelium|down regulation of regeneration of epithelium						rph	2016-03-11T10:59:03Z						biological_process											owl:Class	
GO:1901818	biolink:NamedThing	beta-zeacarotene biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-zeacarotene.	got7fsn_ti	beta-zeacarotene anabolism|beta-zeacarotene biosynthesis|beta-zeacarotene formation|beta-zeacarotene synthesis						yaf	2013-01-22T10:42:12Z						biological_process											owl:Class	
GO:2000940	biolink:NamedThing	negative regulation of plant-type cell wall cellulose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process.	got7fsn_ti	negative regulation of plant-type cell wall polysaccharide breakdown						tt	2011-08-01T02:07:17Z						biological_process											owl:Class	
GO:1902461	biolink:NamedThing	negative regulation of mesenchymal stem cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation.	got7fsn_ti	downregulation of mesenchymal stem cell proliferation|down-regulation of mesenchymal stem cell proliferation|down-regulation of MSC proliferation|inhibition of mesenchymal stem cell proliferation|down regulation of mesenchymal stem cell proliferation|inhibition of MSC proliferation|negative regulation of MSC proliferation|down regulation of MSC proliferation|downregulation of MSC proliferation						pm	2013-10-22T10:01:08Z						biological_process											owl:Class	
GO:1900019	biolink:NamedThing	regulation of protein kinase C activity	Any process that modulates the frequency, rate or extent of protein kinase C activity.	got7fsn_ti	regulation of PKC activity|regulation of PKC						bf	2012-01-11T03:50:47Z						biological_process											owl:Class	
GO:1905364	biolink:NamedThing	regulation of endosomal vesicle fusion	Any process that modulates the frequency, rate or extent of endosomal vesicle fusion.	got7fsn_ti	regulation of endosome vesicle fusion						bc	2016-08-16T11:40:36Z						biological_process											owl:Class	
GO:1901776	biolink:NamedThing	mitomycin C catabolic process	The chemical reactions and pathways resulting in the breakdown of mitomycin C.	got7fsn_ti	mitomycin C breakdown|mitomycin C degradation|mitomycin C catabolism						yaf	2013-01-15T12:11:52Z						biological_process											owl:Class	
GO:1900362	biolink:NamedThing	positive regulation of pentasaccharide transport	Any process that activates or increases the frequency, rate or extent of pentasaccharide transport.	got7fsn_ti	up regulation of pentasaccharide transport|upregulation of pentasaccharide transport|activation of pentasaccharide transport|up-regulation of pentasaccharide transport						tt	2012-04-06T02:19:44Z						biological_process											owl:Class	
GO:1905385	biolink:NamedThing	negative regulation of protein localization to presynapse	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse.	got7fsn_ti	down-regulation of protein localization in presynapse|down regulation of protein localization in presynapse|down-regulation of protein localisation to presynapse|down regulation of protein localization to presynapse|negative regulation of protein localization in presynapse|downregulation of protein localization to presynapse|down-regulation of protein localisation in presynapse|inhibition of protein localisation in presynapse|down-regulation of protein localization to presynapse|downregulation of protein localization in presynapse|downregulation of protein localisation to presynapse|downregulation of protein localisation in presynapse|down regulation of protein localisation to presynapse|inhibition of recruitment of presynaptic proteins|negative regulation of protein localisation in presynapse|negative regulation of protein localisation to presynapse|down-regulation of recruitment of presynaptic proteins|inhibition of protein localization in presynapse|down regulation of recruitment of presynaptic proteins|down regulation of protein localisation in presynapse|downregulation of recruitment of presynaptic proteins|negative regulation of recruitment of presynaptic proteins|inhibition of protein localization to presynapse|inhibition of protein localisation to presynapse						dos	2016-08-18T14:56:08Z						biological_process											owl:Class	
GO:0003395	biolink:NamedThing	neuron migration involved in dendrite retrograde extension	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite.	got7fsn_ti							dph	2009-12-09T09:44:24Z						biological_process											owl:Class	
GO:1903452	biolink:NamedThing	positive regulation of G1 to G0 transition	Any process that activates or increases the frequency, rate or extent of G1 to G0 transition.	got7fsn_ti	positive regulation of establishment of cell quiescence|activation of G1 to G0 transition|up-regulation of G1 to G0 transition|upregulation of establishment of cell quiescence|upregulation of cell cycle quiescence|activation of G1/G0 transition|positive regulation of G1/G0 transition|up regulation of cell cycle quiescence|activation of stationary phase|up-regulation of stationary phase|up regulation of stationary phase|activation of cell cycle quiescence|upregulation of stationary phase|activation of establishment of cell quiescence|up regulation of establishment of cell quiescence|up regulation of G1 to G0 transition|upregulation of G1 to G0 transition|positive regulation of cell cycle quiescence|upregulation of G1/G0 transition|up regulation of G1/G0 transition|up-regulation of G1/G0 transition|up-regulation of cell cycle quiescence|up-regulation of establishment of cell quiescence|positive regulation of stationary phase						di	2014-09-19T22:23:30Z						biological_process											owl:Class	
GO:1905463	biolink:NamedThing	negative regulation of DNA duplex unwinding	Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding.	got7fsn_ti	downregulation of DNA unwinding|inhibition of duplex DNA melting|down regulation of duplex DNA melting|downregulation of DNA duplex unwinding|down-regulation of DNA unwinding|down-regulation of duplex DNA melting|negative regulation of DNA unwinding|down regulation of DNA unwinding|negative regulation of duplex DNA melting|inhibition of DNA unwinding|down regulation of DNA duplex unwinding|downregulation of duplex DNA melting|inhibition of DNA duplex unwinding|down-regulation of DNA duplex unwinding						ans	2016-09-19T11:58:48Z						biological_process											owl:Class	
GO:0014725	biolink:NamedThing	regulation of extraocular skeletal muscle development	Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	got7fsn_ti														biological_process											owl:Class	
GO:0032323	biolink:NamedThing	lipoate catabolic process	The chemical reactions and pathways resulting in the breakdown of lipoate.	got7fsn_ti	lipoic acid catabolism|lipoic acid degradation|lipoic acid breakdown													biological_process											owl:Class	
GO:0016777	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008550	biolink:NamedThing	obsolete tubulin GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An intrinsic activity of alpha-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others.	got7fsn_ti	tubulin GTPase activity				This term was made obsolete because it represents a gene product.	GO:0003924|GO:0007021				True				molecular_function											owl:Class	
GO:0009176	biolink:NamedThing	pyrimidine deoxyribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0001304	biolink:NamedThing	obsolete progressive alteration of chromatin involved in replicative cell aging	OBSOLETE. A process that results in changes in chromatin structure contributing to replicative cell aging.	got7fsn_ti	progressive alteration of chromatin during replicative cell aging|progressive alteration of chromatin during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:2001292	biolink:NamedThing	codeine catabolic process	The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.	got7fsn_ti	codeine catabolism|codeine breakdown|codeine degradation						pr	2012-02-14T01:10:09Z						biological_process											owl:Class	
GO:1905016	biolink:NamedThing	negative regulation of isoleucine-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of isoleucine-tRNA ligase activity.	got7fsn_ti	inhibition of isoleucyl-transfer RNA synthetase activity|downregulation of isoleucyl-tRNA synthetase activity|down regulation of isoleucine-tRNA ligase activity|inhibition of isoleucine-tRNA synthetase activity|down-regulation of isoleucine-tRNA ligase activity|down-regulation of isoleucine translase activity|down regulation of isoleucine translase activity|down-regulation of isoleucine-tRNA synthetase activity|downregulation of isoleucyl-transfer ribonucleate synthetase activity|inhibition of L-isoleucine:tRNAIle ligase (AMP-forming)|downregulation of isoleucyl-transfer RNA synthetase activity|down-regulation of isoleucyl-transfer ribonucleate synthetase activity|down regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|downregulation of isoleucine-tRNA synthetase activity|down regulation of isoleucyl-tRNA synthetase activity|downregulation of isoleucine translase activity|inhibition of isoleucine translase activity|down regulation of isoleucyl-transfer RNA synthetase activity|down regulation of isoleucine-tRNA synthetase activity|negative regulation of isoleucyl-transfer RNA synthetase activity|inhibition of isoleucine-tRNA ligase activity|downregulation of L-isoleucine:tRNAIle ligase (AMP-forming)|down-regulation of isoleucyl-tRNA synthetase activity|down regulation of isoleucine-transfer RNA ligase activity|negative regulation of isoleucine-tRNA synthetase activity|down-regulation of isoleucyl-transfer RNA synthetase activity|downregulation of isoleucine-transfer RNA ligase activity|down-regulation of isoleucine-transfer RNA ligase activity|inhibition of isoleucyl-tRNA synthetase activity|downregulation of isoleucine-tRNA ligase activity|down regulation of isoleucyl-transfer ribonucleate synthetase activity|negative regulation of isoleucyl-transfer ribonucleate synthetase activity|negative regulation of isoleucine-transfer RNA ligase activity|inhibition of isoleucyl-transfer ribonucleate synthetase activity|negative regulation of isoleucyl-tRNA synthetase activity|negative regulation of isoleucine translase activity|inhibition of isoleucine-transfer RNA ligase activity|down-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|negative regulation of L-isoleucine:tRNAIle ligase (AMP-forming)						sl	2016-03-03T19:00:57Z						biological_process											owl:Class	
GO:0002147	biolink:NamedThing	obsolete glucocorticoid receptor import into nucleus	OBSOLETE. The directed movement of a glucocorticoid receptor into the nucleus.	got7fsn_ti	glucocorticoid receptor nuclear translocation				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0042306	hjd	2009-07-09T02:36:09Z		True				biological_process											owl:Class	
GO:1903027	biolink:NamedThing	regulation of opsonization	Any process that modulates the frequency, rate or extent of opsonization.	got7fsn_ti							rl	2014-05-16T17:34:41Z						biological_process											owl:Class	
GO:0030356	biolink:NamedThing	obsolete small cytoplasmic ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	small cytoplasmic ribonucleoprotein|scRNP			GO:1990904	This term was made obsolete because it describes a cellular component rather than a molecular function.					True				molecular_function											owl:Class	
GO:0015561	biolink:NamedThing	rhamnose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in).	got7fsn_ti	rhamnose:hydrogen symporter activity											TC:2.A.7.6		molecular_function											owl:Class	
GO:0010990	biolink:NamedThing	regulation of SMAD protein complex assembly	Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.	got7fsn_ti							tb	2009-06-03T11:28:05Z						biological_process											owl:Class	
GO:0070216	biolink:NamedThing	obsolete MDM4 binding	OBSOLETE. Binding to an isoform of the MDM4 protein, a negative regulator of p53.	got7fsn_ti	MDM4 binding|MDMX binding			GO:0097371	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:0051142	biolink:NamedThing	positive regulation of NK T cell proliferation	Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.	got7fsn_ti	up regulation of NK T cell proliferation|positive regulation of natural T cell proliferation|positive regulation of NK T-cell proliferation|activation of NK T cell proliferation|positive regulation of natural killer T cell proliferation|stimulation of NK T cell proliferation|positive regulation of NK T-lymphocyte proliferation|positive regulation of NK T lymphocyte proliferation|up-regulation of NK T cell proliferation|positive regulation of NKT cell proliferation|positive regulation of NT cell proliferation|upregulation of NK T cell proliferation													biological_process											owl:Class	
GO:1901009	biolink:NamedThing	(S)-scoulerine biosynthetic process	The chemical reactions and pathways resulting in the formation of (S)-scoulerine.	got7fsn_ti	(S)-scoulerine formation|(S)-scoulerine anabolism|(S)-scoulerine biosynthesis|(S)-scoulerine synthesis						yaf	2012-06-15T10:46:17Z						biological_process											owl:Class	
GO:2000544	biolink:NamedThing	regulation of endothelial cell chemotaxis to fibroblast growth factor	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.	got7fsn_ti							ebc	2011-04-03T07:14:04Z						biological_process											owl:Class	
GO:0044110	biolink:NamedThing	obsolete growth involved in symbiotic interaction	OBSOLETE. The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction.	got7fsn_ti	growth on or near surface of other organism during symbiotic interaction|growth on or near surface of other organism involved in symbiotic interaction|growth during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/20273			This term has been obsoleted because it represents an assay for viability, not a real biological process.		jl	2009-07-30T02:22:33Z		True	GO:0044153			biological_process											owl:Class	
GO:1901119	biolink:NamedThing	tobramycin metabolic process	The chemical reactions and pathways involving tobramycin.	got7fsn_ti	tobramycin metabolism						yaf	2012-07-11T03:15:19Z						biological_process											owl:Class	
GO:1903299	biolink:NamedThing	regulation of hexokinase activity	Any process that modulates the frequency, rate or extent of hexokinase activity.	got7fsn_ti	regulation of hexokinase (phosphorylating)|regulation of hexokinase type IV|regulation of ATP:D-hexose 6-phosphotransferase activity|regulation of hexokinase type I activity|regulation of hexokinase type IV glucokinase activity|regulation of ATP-dependent hexokinase activity|regulation of glucose ATP phosphotransferase activity|regulation of hexokinase D|regulation of hexokinase type III activity|regulation of hexokinase type IV (glucokinase) activity|regulation of hexokinase type II activity						mr	2014-08-15T23:17:53Z						biological_process											owl:Class	
GO:1900675	biolink:NamedThing	regulation of F-9775B biosynthetic process	Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process.	got7fsn_ti	regulation of F-9775B biosynthesis|regulation of F-9775B synthesis|regulation of F-9775B formation|regulation of F-9775B anabolism						di	2012-05-22T04:26:31Z						biological_process											owl:Class	
GO:0140049	biolink:NamedThing	regulation of endocardial cushion to mesenchymal transition	Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition.	got7fsn_ti							pg	2017-06-23T15:57:00Z						biological_process											owl:Class	
GO:0045680	biolink:NamedThing	negative regulation of R8 cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation.	got7fsn_ti	negative regulation of R8 differentiation|down-regulation of R8 differentiation|downregulation of R8 differentiation|down regulation of R8 differentiation|inhibition of R8 differentiation													biological_process											owl:Class	
GO:1900677	biolink:NamedThing	positive regulation of F-9775B biosynthetic process	Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process.	got7fsn_ti	upregulation of F-9775B synthesis|activation of F-9775B biosynthetic process|positive regulation of F-9775B anabolism|up regulation of F-9775B biosynthesis|activation of F-9775B biosynthesis|up-regulation of F-9775B biosynthetic process|upregulation of F-9775B biosynthetic process|positive regulation of F-9775B synthesis|up regulation of F-9775B synthesis|upregulation of F-9775B biosynthesis|activation of F-9775B synthesis|upregulation of F-9775B formation|positive regulation of F-9775B biosynthesis|activation of F-9775B formation|up regulation of F-9775B anabolism|up-regulation of F-9775B formation|up-regulation of F-9775B biosynthesis|up-regulation of F-9775B anabolism|up-regulation of F-9775B synthesis|up regulation of F-9775B formation|up regulation of F-9775B biosynthetic process|upregulation of F-9775B anabolism|positive regulation of F-9775B formation|activation of F-9775B anabolism						di	2012-05-22T04:27:01Z						biological_process											owl:Class	
GO:1903340	biolink:NamedThing	positive regulation of cell wall organization or biogenesis	Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis.	got7fsn_ti	up-regulation of cell wall organization or biogenesis|up-regulation of cell wall organization or biogenesis at cellular level|upregulation of cell wall organization or biogenesis at cellular level|up-regulation of cell wall organisation or biogenesis|activation of cellular cell wall organisation or biogenesis|up regulation of cellular cell wall organization or biogenesis|up-regulation of cellular cell wall organisation or biogenesis|up regulation of cell wall organisation or biogenesis|up regulation of cell wall organization or biogenesis|positive regulation of cellular cell wall organisation or biogenesis|upregulation of cellular cell wall organization or biogenesis|positive regulation of cell wall organisation or biogenesis|upregulation of cellular cell wall organisation or biogenesis|positive regulation of cellular cell wall organization or biogenesis|positive regulation of cell wall organization or biogenesis at cellular level|activation of cell wall organisation or biogenesis|upregulation of cell wall organization or biogenesis|up-regulation of cellular cell wall organization or biogenesis|activation of cell wall organization or biogenesis|activation of cellular cell wall organization or biogenesis|up regulation of cell wall organization or biogenesis at cellular level|activation of cell wall organization or biogenesis at cellular level|upregulation of cell wall organisation or biogenesis|up regulation of cellular cell wall organisation or biogenesis						vw	2014-08-18T13:21:06Z						biological_process											owl:Class	
GO:1903197	biolink:NamedThing	positive regulation of L-dopa biosynthetic process	Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process.	got7fsn_ti	activation of L-dopa biosynthetic process|up regulation of L-dopa biosynthesis|up-regulation of L-dopa formation|up-regulation of L-dopa anabolism|positive regulation of L-dopa anabolism|activation of L-dopa anabolism|up regulation of L-dopa synthesis|positive regulation of L-dopa biosynthesis|upregulation of L-dopa biosynthetic process|up regulation of L-dopa biosynthetic process|upregulation of L-dopa formation|up regulation of L-dopa formation|upregulation of L-dopa synthesis|activation of L-dopa synthesis|activation of L-dopa formation|up-regulation of L-dopa biosynthesis|upregulation of L-dopa anabolism|up regulation of L-dopa anabolism|positive regulation of L-dopa formation|up-regulation of L-dopa biosynthetic process|positive regulation of L-dopa synthesis|activation of L-dopa biosynthesis|up-regulation of L-dopa synthesis|upregulation of L-dopa biosynthesis						bf	2014-07-21T09:12:49Z						biological_process											owl:Class	
GO:1905029	biolink:NamedThing	positive regulation of membrane depolarization during AV node cell action potential	Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential.	got7fsn_ti	activation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|upregulation of membrane depolarization during AV node cardiac muscle cell action potential|up-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up-regulation of membrane depolarization during AV node cardiac muscle cell action potential|activation of membrane depolarization during AV node cardiac muscle cell action potential|up-regulation of membrane depolarization during AV node cell action potential|upregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up regulation of membrane depolarization during AV node cardiac muscle cell action potential|up regulation of membrane depolarization during AV node cell action potential|positive regulation of membrane depolarization during AV node cardiac muscle cell action potential|activation of membrane depolarization during AV node cell action potential|upregulation of membrane depolarization during AV node cell action potential|up regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|positive regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential						rph	2016-03-04T13:46:24Z						biological_process											owl:Class	
GO:0051206	biolink:NamedThing	silicate metabolic process	The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.	got7fsn_ti	silicate metabolism													biological_process											owl:Class	
GO:0031940	biolink:NamedThing	obsolete positive regulation of chromatin silencing at telomere	OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres.	got7fsn_ti	stimulation of chromatin silencing at telomere|activation of chromatin silencing at telomere|up-regulation of chromatin silencing at telomere|positive regulation of heterochromatic silencing at telomere|up regulation of chromatin silencing at telomere|upregulation of chromatin silencing at telomere	https://github.com/geneontology/go-ontology/issues/22027			This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.					True				biological_process											owl:Class	
GO:1904077	biolink:NamedThing	negative regulation of estrogen biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process.	got7fsn_ti	down regulation of estrogen biosynthetic process|inhibition of estrogen biosynthetic process|inhibition of estrogen formation|inhibition of oestrogen biosynthetic process|down-regulation of estrogen anabolism|downregulation of oestrogen biosynthesis|negative regulation of estrogen formation|down-regulation of oestrogen biosynthesis|down regulation of oestrogen biosynthesis|inhibition of estrogen synthesis|inhibition of estrogen anabolism|down-regulation of estrogen biosynthetic process|down-regulation of estrogen synthesis|negative regulation of estrogen anabolism|downregulation of estrogen anabolism|negative regulation of estrogen synthesis|inhibition of oestrogen biosynthesis|downregulation of estrogen biosynthesis|down-regulation of oestrogen biosynthetic process|down regulation of oestrogen biosynthetic process|negative regulation of oestrogen biosynthesis|negative regulation of estrogen biosynthesis|down-regulation of estrogen biosynthesis|down regulation of estrogen formation|down regulation of estrogen anabolism|downregulation of estrogen biosynthetic process|downregulation of estrogen formation|down regulation of estrogen biosynthesis|down-regulation of estrogen formation|negative regulation of oestrogen biosynthetic process|downregulation of oestrogen biosynthetic process|inhibition of estrogen biosynthesis|down regulation of estrogen synthesis|downregulation of estrogen synthesis						tb	2015-03-20T16:56:20Z						biological_process											owl:Class	
GO:0010693	biolink:NamedThing	negative regulation of alkaline phosphatase activity	Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.	got7fsn_ti														biological_process											owl:Class	
GO:0032087	biolink:NamedThing	regulation of type IV site-specific deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity.	got7fsn_ti	regulation of type IV restriction endodeoxyribonuclease activity|type IV restriction endodeoxyribonuclease regulator|type IV restriction enzyme regulator													biological_process											owl:Class	
GO:0015613	biolink:NamedThing	obsolete galactose/glucose (methylgalactoside) porter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	galactose/glucose (methylgalactoside) porter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0005354|GO:0015291|GO:0015592|GO:0005355				True				molecular_function											owl:Class	
GO:1900754	biolink:NamedThing	4-hydroxyphenylacetate transport	The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	2-(4-hydroxyphenyl)ethanoate transport|(p-hydroxyphenyl)acetate transport|(4-hydroxyphenyl)acetate transport|4-hydroxybenzeneacetate transport						jl	2012-05-29T02:59:02Z						biological_process											owl:Class	
GO:0031309	biolink:NamedThing	integral component of nuclear outer membrane	The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to nuclear outer membrane													cellular_component											owl:Class	
GO:0106190	biolink:NamedThing	obsolete translocase activity acting on hydrons linked to a decarboxylation reaction	OBSOLETE. Catalysis of the translocation of hydrons linked to a decarboxylation reaction.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-07T18:17:17Z		True		EC:7.1.4.-		molecular_function											owl:Class	
GO:0070965	biolink:NamedThing	positive regulation of neutrophil mediated killing of fungus	Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.	got7fsn_ti	upregulation of neutrophil mediated killing of fungus|up regulation of neutrophil mediated killing of fungus|activation of neutrophil mediated killing of fungus|stimulation of neutrophil mediated killing of fungus|up-regulation of neutrophil mediated killing of fungus						mah	2009-10-01T02:28:49Z						biological_process											owl:Class	
GO:0042415	biolink:NamedThing	norepinephrine metabolic process	The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.	got7fsn_ti	levarterenol metabolism|noradrenaline metabolic process|levarterenol metabolic process|noradrenaline metabolism|norepinephrine metabolism													biological_process											owl:Class	
GO:0061853	biolink:NamedThing	regulation of neuroblast migration	Any process that modulates the frequency, rate or extent of neuroblast migration.	got7fsn_ti							dph	2017-03-08T18:17:07Z						biological_process											owl:Class	
GO:1903428	biolink:NamedThing	positive regulation of reactive oxygen species biosynthetic process	Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.	got7fsn_ti	up-regulation of reactive oxygen species biosynthesis|upregulation of reactive oxygen species anabolism|up regulation of reactive oxygen species synthesis|activation of reactive oxygen species biosynthesis|up-regulation of reactive oxygen species formation|up-regulation of reactive oxygen species synthesis|up regulation of reactive oxygen species biosynthesis|positive regulation of ROS generation|positive regulation of reactive oxygen species biosynthesis|up-regulation of reactive oxygen species generation|upregulation of reactive oxygen species biosynthesis|activation of reactive oxygen species formation|up-regulation of ROS formation|activation of reactive oxygen species biosynthetic process|up-regulation of reactive oxygen species biosynthetic process|activation of reactive oxygen species synthesis|upregulation of ROS generation|upregulation of reactive oxygen species synthesis|upregulation of ROS formation|positive regulation of reactive oxygen species synthesis|activation of ROS generation|up regulation of reactive oxygen species biosynthetic process|up-regulation of ROS generation|positive regulation of reactive oxygen species generation|up regulation of ROS generation|activation of reactive oxygen species generation|positive regulation of reactive oxygen species formation|up regulation of reactive oxygen species anabolism|upregulation of reactive oxygen species biosynthetic process|upregulation of reactive oxygen species formation|up regulation of ROS formation|activation of reactive oxygen species anabolism|up-regulation of reactive oxygen species anabolism|positive regulation of ROS formation|up regulation of reactive oxygen species formation|up regulation of reactive oxygen species generation|activation of ROS formation|positive regulation of reactive oxygen species anabolism|upregulation of reactive oxygen species generation						bf	2014-09-11T10:02:05Z						biological_process											owl:Class	
GO:1905313	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in heart development	Any transforming growth factor beta receptor signaling pathway that is involved in heart development.	got7fsn_ti	transforming growth factor beta receptor signalling pathway involved in cardiac development|transforming growth factor beta receptor signalling pathway involved in dorsal vessel development|TGF-beta receptor signalling pathway involved in heart development|transforming growth factor beta receptor signaling pathway involved in dorsal vessel development|TGF-beta receptor signalling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in cardiac development|TGF-beta receptor signaling pathway involved in heart development|transforming growth factor beta receptor signalling pathway involved in heart development|TGFbeta receptor signalling pathway involved in heart development|TGFbeta receptor signaling pathway involved in heart development|TGFbeta receptor signalling pathway involved in cardiac development|TGF-beta receptor signalling pathway involved in cardiac development|TGFbeta receptor signalling pathway involved in dorsal vessel development|TGF-beta receptor signaling pathway involved in dorsal vessel development|TGF-beta receptor signaling pathway involved in cardiac development|transforming growth factor beta receptor signaling pathway involved in cardiac development						rl	2016-07-11T17:45:38Z						biological_process											owl:Class	
GO:0046212	biolink:NamedThing	obsolete methyl ethyl ketone biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints.	got7fsn_ti	methyl ethyl ketone biosynthesis|methyl ethyl ketone synthesis|methyl ethyl ketone biosynthetic process|methyl ethyl ketone formation|methyl ethyl ketone anabolism			GO:0018928	This term was made obsolete because methyl ethyl ketone is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0001801	biolink:NamedThing	positive regulation of type IIb hypersensitivity	Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.	got7fsn_ti	up regulation of type IIb hypersensitivity|up-regulation of type IIb hypersensitivity|activation of type IIb hypersensitivity|upregulation of type IIb hypersensitivity|stimulation of type IIb hypersensitivity													biological_process											owl:Class	
GO:1902218	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.	got7fsn_ti							rl	2013-06-13T10:19:07Z						biological_process											owl:Class	
GO:1904843	biolink:NamedThing	cellular response to nitroglycerin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.	got7fsn_ti	cellular response to trinitroglycerol|cellular response to nitroglycerine|cellular response to nitroglycerol|cellular response to trinitroglycerin						sl	2015-12-07T18:30:55Z						biological_process											owl:Class	
GO:1901732	biolink:NamedThing	quercetin metabolic process	The chemical reactions and pathways involving quercetin.	got7fsn_ti	quercetin metabolism						yaf	2013-01-11T10:25:11Z						biological_process											owl:Class	
GO:0070804	biolink:NamedThing	positive regulation of metula development	Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.	got7fsn_ti							mah	2009-07-08T04:38:33Z						biological_process											owl:Class	
GO:0051569	biolink:NamedThing	regulation of histone H3-K4 methylation	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.	got7fsn_ti														biological_process											owl:Class	
GO:0035949	biolink:NamedThing	obsolete positive regulation of gluconeogenesis by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of gluconeogenesis by down regulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by negative regulation of transcription from Pol II promoter|positive regulation of gluconeogenesis by downregulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by negative regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by downregulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by downregulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by negative regulation of transcription from Pol II promoter|positive regulation of gluconeogenesis by down-regulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by inhibition of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by negative regulation of transcription from Pol II promoter|positive regulation of glucose biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by down regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by down regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:1901871	biolink:NamedThing	ecgonone methyl ester catabolic process	The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester.	got7fsn_ti	ecgonone methyl ester catabolism|ecgonone methyl ester degradation|ecgonone methyl ester breakdown						ms	2013-02-04T11:58:34Z						biological_process											owl:Class	
GO:1902252	biolink:NamedThing	positive regulation of erythrocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process.	got7fsn_ti	activation of RBC apoptotic process|activation of red blood cell apoptotic process|upregulation of RBC apoptosis|upregulation of RBC apoptotic process|activation of RBC apoptosis|up regulation of RBC apoptotic process|up regulation of RBC apoptosis|up-regulation of RBC apoptotic process|up regulation of red blood cell apoptosis|up-regulation of erythrocyte apoptosis|positive regulation of RBC apoptotic process|upregulation of erythrocyte apoptosis|up-regulation of red blood cell apoptotic process|activation of red blood cell apoptosis|positive regulation of erythrocyte apoptosis|activation of erythrocyte apoptosis|positive regulation of red blood cell apoptotic process|upregulation of erythrocyte apoptotic process|positive regulation of red blood cell apoptosis|upregulation of red blood cell apoptotic process|upregulation of red blood cell apoptosis|up regulation of erythrocyte apoptotic process|activation of erythrocyte apoptotic process|up regulation of erythrocyte apoptosis|up-regulation of RBC apoptosis|up-regulation of red blood cell apoptosis|positive regulation of RBC apoptosis|up regulation of red blood cell apoptotic process|up-regulation of erythrocyte apoptotic process						rl	2013-06-20T19:31:04Z						biological_process											owl:Class	
GO:1905852	biolink:NamedThing	positive regulation of backward locomotion	Any process that activates or increases the frequency, rate or extent of backward locomotion.	got7fsn_ti	up regulation of backward locomotion|up-regulation of backward locomotion|upregulation of backward locomotion|activation of backward locomotion						rz	2017-01-23T11:04:25Z						biological_process											owl:Class	
GO:2000462	biolink:NamedThing	obsolete positive regulation of eukaryotic cell surface binding	OBSOLETE. Any process that activates or increases the frequency, rate or extent of eukaryotic cell surface binding.	got7fsn_ti	positive regulation of eukaryotic cell surface binding				This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion.	GO:0031347|GO:1900122	yaf	2011-03-04T12:00:49Z		True				biological_process											owl:Class	
GO:1904244	biolink:NamedThing	positive regulation of pancreatic trypsinogen secretion	Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion.	got7fsn_ti	upregulation of pancreatic trypsinogen release|up regulation of pancreatic trypsinogen release|up-regulation of pancreatic trypsinogen secretion|positive regulation of pancreatic trypsinogen release|upregulation of pancreatic trypsinogen secretion|activation of pancreatic trypsinogen release|up-regulation of pancreatic trypsinogen release|up regulation of pancreatic trypsinogen secretion|activation of pancreatic trypsinogen secretion						sl	2015-05-18T19:49:32Z						biological_process											owl:Class	
GO:1904466	biolink:NamedThing	positive regulation of matrix metallopeptidase secretion	Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion.	got7fsn_ti	positive regulation of MMP secretion|activation of matrix metalloproteinase secretion|up-regulation of matrix metalloproteinase secretion|up regulation of MMP secretion|up regulation of matrix metallopeptidase secretion|upregulation of MMP secretion|upregulation of matrix metalloproteinase secretion|activation of MMP secretion|upregulation of matrix metallopeptidase secretion|up-regulation of MMP secretion|positive regulation of matrix metalloproteinase secretion|up-regulation of matrix metallopeptidase secretion|activation of matrix metallopeptidase secretion|up regulation of matrix metalloproteinase secretion						sl	2015-07-09T19:46:30Z						biological_process											owl:Class	
GO:1903255	biolink:NamedThing	hercynylselenocysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of hercynylselenocysteine.	got7fsn_ti	hercynylselenocysteine synthesis|hercynylselenocysteine formation|hercynylselenocysteine anabolism|hercynylselenocysteine biosynthesis						mah	2014-08-06T09:14:16Z						biological_process											owl:Class	
GO:2000404	biolink:NamedThing	regulation of T cell migration	Any process that modulates the frequency, rate or extent of T cell migration.	got7fsn_ti	regulation of T-cell migration|regulation of T-lymphocyte migration|regulation of T lymphocyte migration						mah	2011-02-23T10:48:24Z						biological_process											owl:Class	
GO:0120058	biolink:NamedThing	positive regulation of small intestinal transit	Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.	got7fsn_ti	positive regulation of small intestine transit|positive regulation of small bowel transit						krc	2017-06-13T20:58:23Z						biological_process											owl:Class	
GO:1905427	biolink:NamedThing	intracellular signal transduction involved in positive regulation of cell growth	Any intracellular signal transduction that is involved in positive regulation of cell growth.	got7fsn_ti	signal transmission via intracellular cascade involved in upregulation of cell growth|protein kinase cascade involved in activation of cell growth|signal transmission via intracellular cascade involved in up-regulation of cell growth|intracellular signaling cascade involved in up-regulation of cell growth|intracellular signal transduction pathway involved in upregulation of cell growth|protein kinase cascade involved in stimulation of cell growth|signal transduction via intracellular signaling cascade involved in activation of cell growth|intracellular protein kinase cascade involved in up regulation of cell growth|intracellular signaling chain involved in up regulation of cell growth|intracellular signaling pathway involved in activation of cell growth|signal transduction via intracellular signaling cascade involved in stimulation of cell growth|signal transmission via intracellular cascade involved in positive regulation of cell growth|intracellular protein kinase cascade involved in up-regulation of cell growth|intracellular protein kinase cascade involved in positive regulation of cell growth|intracellular protein kinase cascade involved in stimulation of cell growth|intracellular signal transduction pathway involved in up-regulation of cell growth|intracellular signaling pathway involved in up regulation of cell growth|intracellular protein kinase cascade involved in activation of cell growth|signal transduction via intracellular signaling cascade involved in upregulation of cell growth|intracellular signal transduction involved in up-regulation of cell growth|intracellular signal transduction involved in upregulation of cell growth|intracellular signal transduction pathway involved in activation of cell growth|intracellular signaling chain involved in positive regulation of cell growth|intracellular signal transduction pathway involved in up regulation of cell growth|intracellular signaling chain involved in activation of cell growth|protein kinase cascade involved in up-regulation of cell growth|intracellular signaling cascade involved in positive regulation of cell growth|intracellular signaling pathway involved in positive regulation of cell growth|signal transduction via intracellular signaling cascade involved in up-regulation of cell growth|intracellular signaling chain involved in up-regulation of cell growth|intracellular signaling cascade involved in activation of cell growth|intracellular signaling chain involved in stimulation of cell growth|intracellular signal transduction pathway involved in positive regulation of cell growth|intracellular signaling cascade involved in up regulation of cell growth|signal transmission via intracellular cascade involved in activation of cell growth|intracellular signal transduction involved in stimulation of cell growth|intracellular signal transduction involved in up regulation of cell growth|intracellular signaling cascade involved in stimulation of cell growth|protein kinase cascade involved in upregulation of cell growth|intracellular signal transduction involved in activation of cell growth|signal transmission via intracellular cascade involved in up regulation of cell growth|intracellular signal transduction pathway involved in stimulation of cell growth|intracellular protein kinase cascade involved in upregulation of cell growth|intracellular signaling chain involved in upregulation of cell growth|signal transduction via intracellular signaling cascade involved in up regulation of cell growth|signal transduction via intracellular signaling cascade involved in positive regulation of cell growth|signal transmission via intracellular cascade involved in stimulation of cell growth|intracellular signaling pathway involved in up-regulation of cell growth|protein kinase cascade involved in up regulation of cell growth|intracellular signaling pathway involved in upregulation of cell growth|protein kinase cascade involved in positive regulation of cell growth|intracellular signaling cascade involved in upregulation of cell growth|intracellular signaling pathway involved in stimulation of cell growth						dph	2016-09-07T18:15:01Z						biological_process											owl:Class	
GO:0031447	biolink:NamedThing	negative regulation of fast-twitch skeletal muscle fiber contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction.	got7fsn_ti	down regulation of fast-twitch skeletal muscle contraction|negative regulation of fast-twitch skeletal muscle contraction|down-regulation of fast-twitch skeletal muscle contraction|inhibition of fast-twitch skeletal muscle contraction|downregulation of fast-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:0045768	biolink:NamedThing	obsolete positive regulation of anti-apoptosis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of anti-apoptosis.	got7fsn_ti	up-regulation of anti-apoptosis|positive regulation of anti-apoptosis|activation of anti-apoptosis|stimulation of anti-apoptosis|up regulation of anti-apoptosis|upregulation of anti-apoptosis				This term was made obsolete because it was ill-defined.					True				biological_process											owl:Class	
GO:0010195	biolink:NamedThing	obsolete microRNA biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity.	got7fsn_ti	microRNA synthesis|miRNA biosynthesis|microRNA biosynthesis|microRNA anabolism|microRNA biosynthetic process|miRNA biosynthetic process|microRNA formation			GO:0035196	This term was made obsolete because it represents a process that is not known to occur.					True				biological_process											owl:Class	
GO:0031581	biolink:NamedThing	hemidesmosome assembly	Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.	got7fsn_ti														biological_process											owl:Class	
GO:1901370	biolink:NamedThing	response to glutathione	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.	got7fsn_ti							mah	2012-09-21T13:59:24Z						biological_process											owl:Class	
GO:1904085	biolink:NamedThing	obsolete positive regulation of epiboly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of epiboly.	got7fsn_ti	up-regulation of epiboly|activation of epiboly|upregulation of epiboly|positive regulation of epiboly|up regulation of epiboly				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2015-03-25T10:53:47Z		True				biological_process											owl:Class	
GO:0019683	biolink:NamedThing	glyceraldehyde-3-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.	got7fsn_ti	glyceraldehyde 3-phosphate catabolism|glyceraldehyde-3-phosphate breakdown|glyceraldehyde-3-phosphate degradation|glyceraldehyde-3-phosphate catabolism|glyceraldehyde 3-phosphate catabolic process													biological_process											owl:Class	
GO:1900470	biolink:NamedThing	positive regulation of phosphatidylserine biosynthetic process	Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process.	got7fsn_ti	positive regulation of phosphatidylserine synthesis|up-regulation of phosphatidylserine formation|activation of phosphatidylserine biosynthetic process|upregulation of phosphatidylserine biosynthesis|positive regulation of phosphatidylserine biosynthesis|activation of phosphatidylserine anabolism|positive regulation of phosphatidylserine formation|up-regulation of phosphatidylserine anabolism|up regulation of phosphatidylserine synthesis|positive regulation of phosphatidylserine anabolism|up regulation of phosphatidylserine biosynthesis|upregulation of phosphatidylserine biosynthetic process|up regulation of phosphatidylserine biosynthetic process|upregulation of phosphatidylserine anabolism|activation of phosphatidylserine formation|up regulation of phosphatidylserine anabolism|activation of phosphatidylserine biosynthesis|up-regulation of phosphatidylserine synthesis|upregulation of phosphatidylserine formation|up-regulation of phosphatidylserine biosynthesis|up-regulation of phosphatidylserine biosynthetic process|upregulation of phosphatidylserine synthesis|activation of phosphatidylserine synthesis|up regulation of phosphatidylserine formation						dgf	2012-05-01T08:01:19Z						biological_process											owl:Class	
GO:0061870	biolink:NamedThing	positive regulation of hepatic stellate cell migration	Any process that increases the frequency, rate or extent of hepatic stellate cell migration.	got7fsn_ti							dph	2017-05-01T13:17:23Z						biological_process											owl:Class	
GO:0015654	biolink:NamedThing	tellurite transmembrane transporter activity	Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals.	got7fsn_ti	tellurite-resistance uptake transmembrane transporter activity|tellurite-resistance uptake permease activity|tellurite uptake transmembrane transporter activity										GO:0015118			molecular_function											owl:Class	
GO:0100054	biolink:NamedThing	obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates flocculation via cell wall protein-carbohydrate interaction.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0005012	biolink:NamedThing	obsolete Neu/ErbB-2 receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Neu/ErbB-2 receptor activity				This term was made obsolete because it represents a class of receptor rather than an activity.	GO:0043125				True				molecular_function											owl:Class	
GO:1904333	biolink:NamedThing	positive regulation of error-prone translesion synthesis	Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.	got7fsn_ti	up-regulation of mutagenic PRR|positive regulation of mutagenic PRR|up-regulation of error-prone postreplication DNA repair|positive regulation of error-prone postreplication DNA repair|upregulation of error-prone translesion synthesis|up regulation of mutagenic PRR|activation of error-prone translesion synthesis|activation of mutagenic postreplication DNA repair|up regulation of mutagenic postreplication DNA repair|up regulation of error-prone translesion synthesis|upregulation of mutagenic PRR|upregulation of mutagenic postreplication DNA repair|up-regulation of error-prone translesion synthesis|upregulation of error-prone postreplication DNA repair|activation of mutagenic PRR|up-regulation of mutagenic postreplication DNA repair|up regulation of error-prone postreplication DNA repair|activation of error-prone postreplication DNA repair|positive regulation of mutagenic postreplication DNA repair						kmv	2015-06-11T16:25:10Z						biological_process											owl:Class	
GO:0070630	biolink:NamedThing	(1->4)-alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.	got7fsn_ti	(1->4)-alpha-D-glucan formation|alpha-1,4 glucan synthesis|1,4-alpha-glucan formation|alpha-1,4 glucan formation|(1->4)-alpha-D-glucan synthesis|1,4-alpha-glucan anabolism|1,4-alpha-glucan synthesis|(1->4)-alpha-D-glucan anabolism|1,4-alpha-glucan biosynthesis|alpha-1,4 glucan anabolism|alpha-1,4 glucan biosynthesis|alpha-1,4 glucan biosynthetic process|1,4-alpha-glucan biosynthetic process|(1->4)-alpha-D-glucan biosynthesis						mah	2009-05-01T04:46:34Z						biological_process											owl:Class	
GO:0036112	biolink:NamedThing	medium-chain fatty-acyl-CoA metabolic process	The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.	got7fsn_ti	medium-chain fatty acyl-CoA metabolism|medium-chain fatty acyl CoA metabolic process						bf	2012-02-15T11:12:19Z						biological_process											owl:Class	
GO:1904106	biolink:NamedThing	protein localization to microvillus	A process in which a protein is transported to, or maintained in, a location within a microvillus.	got7fsn_ti	protein localization in microvillus|protein localisation in microvillus|protein localisation to microvillus						kmv	2015-04-01T18:14:41Z						biological_process											owl:Class	
GO:0110004	biolink:NamedThing	positive regulation of tRNA methylation	Any process that activates or increases the frequency, rate or extent of tRNA methylation.	got7fsn_ti							kmv							biological_process											owl:Class	
GO:0001303	biolink:NamedThing	obsolete nucleolar fragmentation involved in replicative aging	OBSOLETE. A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells.	got7fsn_ti	nucleolar fragmentation during replicative aging|nucleolar fragmentation during replicative ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:1902799	biolink:NamedThing	regulation of phosphodiesterase I activity	Any process that modulates the frequency, rate or extent of phosphodiesterase I activity.	got7fsn_ti	regulation of orthophosphoric diester phosphohydrolase activity|regulation of alkaline phosphodiesterase activity|regulation of 5'NPDE activity|regulation of 5'-PDE activity|regulation of 5'-phosphodiesterase activity|regulation of oligonucleate 5'-nucleotidohydrolase activity|regulation of 5'-PDase activity|regulation of exonuclease I activity|regulation of phosphodiesterase activity|regulation of 5'-nucleotide phosphodiesterase activity|regulation of 5'-NPDase activity|regulation of 5'-exonuclease activity|regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|regulation of PDE I activity|regulation of nucleotide pyrophosphatase/phosphodiesterase I activity						al	2014-03-25T08:55:48Z						biological_process											owl:Class	
GO:0098533	biolink:NamedThing	ATPase dependent transmembrane transport complex	A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.	got7fsn_ti					The location of this complex is implicit in its activity, so its location is asserted as a regular relationship rather than as a part of an intersection.		dos	2013-10-22T12:12:52Z						cellular_component											owl:Class	
GO:0098958	biolink:NamedThing	retrograde axonal transport of mitochondrion	The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse.	got7fsn_ti	retrograde axon transport of mitochondria													biological_process											owl:Class	
GO:0008148	biolink:NamedThing	obsolete negative transcription elongation factor activity	OBSOLETE. Any activity that decreases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation.	got7fsn_ti	negative transcription elongation factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0032785				True				molecular_function											owl:Class	
CHEBI:63137	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903407	biolink:NamedThing	negative regulation of P-type sodium:potassium-exchanging transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.	got7fsn_ti	down regulation of (Na+ + K+)-ATPase activity|inhibition of ATP phosphohydrolase (Na+/K+-exchanging)|negative regulation of Na,K-activated ATPase activity|down-regulation of sodium:potassium-exchanging ATPase activity|down regulation of (Na+ + K+)-activated ATPase activity|down regulation of sodium:potassium exchanging ATPase activity|downregulation of sodium:potassium exchanging ATPase activity|down-regulation of ATP phosphohydrolase (Na+/K+-exchanging)|downregulation of Na+,K+-ATPase activity|down regulation of Na,K-activated ATPase activity|negative regulation of (Na+ + K+)-activated ATPase activity|down regulation of Na+/K+-exchanging ATPase activity|downregulation of Na,K-activated ATPase activity|down regulation of sodium:potassium-exchanging ATPase activity|inhibition of (Na+ + K+)-activated ATPase activity|down regulation of Na,K-pump|down-regulation of Na,K-pump|down-regulation of sodium:potassium exchanging ATPase activity|negative regulation of Na,K-pump|downregulation of (Na+ + K+)-ATPase activity|inhibition of sodium/potassium-exchanging ATPase activity|down-regulation of sodium/potassium-transporting ATPase activity|inhibition of Na+,K+-ATPase activity|down-regulation of Na(+)/K(+)-exchanging ATPase activity|downregulation of Na(+)/K(+)-exchanging ATPase activity|downregulation of Na(+)/K(+)-ATPase activity|inhibition of Na(+)/K(+)-exchanging ATPase activity|negative regulation of Na(+)/K(+)-exchanging ATPase activity|inhibition of sodium/potassium-transporting ATPase activity|negative regulation of Na(+)/K(+)-ATPase activity|down regulation of Na(+)/K(+)-exchanging ATPase activity|negative regulation of Na+,K+-ATPase activity|downregulation of Na,K-pump|down regulation of ATP phosphohydrolase (Na+/K+-exchanging)|down-regulation of Na+,K+ pump|inhibition of (Na+ + K+)-ATPase activity|downregulation of sodium:potassium-exchanging ATPase activity|negative regulation of sodium/potassium-exchanging ATPase activity|inhibition of Na+/K+-ATPase activity|downregulation of sodium/potassium-exchanging ATPase activity|inhibition of sodium:potassium exchanging ATPase activity|downregulation of Na+,K+ pump|downregulation of (Na+ + K+)-activated ATPase activity|down regulation of sodium/potassium-transporting ATPase activity|negative regulation of sodium:potassium-exchanging ATPase activity|negative regulation of (Na+ + K+)-ATPase activity|inhibition of Na,K-pump|negative regulation of Na+,K+ pump|inhibition of Na,K-activated ATPase activity|down-regulation of Na+,K+-ATPase activity|down-regulation of Na,K-activated ATPase activity|down-regulation of Na+/K+-ATPase activity|down regulation of Na(+)/K(+)-ATPase activity|inhibition of sodium:potassium-exchanging ATPase activity|down regulation of Na+,K+ pump|downregulation of Na+/K+-ATPase activity|negative regulation of sodium:potassium exchanging ATPase activity|negative regulation of sodium/potassium-transporting ATPase activity|negative regulation of Na+/K+-exchanging ATPase activity|down-regulation of Na(+)/K(+)-ATPase activity|down-regulation of Na+/K+-exchanging ATPase activity|down regulation of Na+/K+-ATPase activity|negative regulation of Na+/K+-ATPase activity|down-regulation of (Na+ + K+)-ATPase activity|down-regulation of sodium/potassium-exchanging ATPase activity|down-regulation of (Na+ + K+)-activated ATPase activity|negative regulation of ATP phosphohydrolase (Na+/K+-exchanging)|down regulation of sodium/potassium-exchanging ATPase activity|inhibition of Na+,K+ pump|inhibition of Na+/K+-exchanging ATPase activity|inhibition of Na(+)/K(+)-ATPase activity|downregulation of Na+/K+-exchanging ATPase activity|down regulation of Na+,K+-ATPase activity|downregulation of sodium/potassium-transporting ATPase activity|downregulation of ATP phosphohydrolase (Na+/K+-exchanging)						mr	2014-09-02T19:45:16Z						biological_process											owl:Class	
GO:2000156	biolink:NamedThing	regulation of retrograde vesicle-mediated transport, Golgi to ER	Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER.	got7fsn_ti	regulation of retrograde (Golgi to ER) transport|regulation of retrograde transport, Golgi to endoplasmic reticulum|regulation of cis-Golgi to rough endoplasmic reticulum transport|regulation of retrograde transport, Golgi to ER|regulation of cis-Golgi to rough ER transport|regulation of retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum|regulation of cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|regulation of cis-Golgi to rough ER vesicle-mediated transport						mah	2010-10-04T12:46:35Z						biological_process											owl:Class	
GO:0075157	biolink:NamedThing	obsolete positive regulation of G protein-coupled receptor signaling pathway in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of G-protein coupled receptor protein signaling pathway in response to host|positive regulation of G-protein coupled receptor protein signalling pathway in response to host|positive regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0042732	biolink:NamedThing	D-xylose metabolic process	The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide.	got7fsn_ti	D-xylose metabolism													biological_process											owl:Class	
GO:0003366	biolink:NamedThing	cell-matrix adhesion involved in ameboidal cell migration	The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell.	got7fsn_ti							dph	2009-12-08T04:54:33Z						biological_process											owl:Class	
GO:1905565	biolink:NamedThing	obsolete regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	OBSOLETE. Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport.	got7fsn_ti	regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|regulation of receptor-mediated endocytosis of LDL				This term was obsoleted at the TermGenie Gatekeeper stage.		nc	2016-10-18T10:58:29Z		True				biological_process											owl:Class	
GO:1903517	biolink:NamedThing	negative regulation of single strand break repair	Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair.	got7fsn_ti	inhibition of single strand break repair|down-regulation of single strand break repair|down regulation of single strand break repair|downregulation of single strand break repair						rl	2014-10-06T10:59:01Z						biological_process											owl:Class	
GO:0045607	biolink:NamedThing	regulation of inner ear auditory receptor cell differentiation	Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.	got7fsn_ti	regulation of auditory receptor cell differentiation|regulation of auditory hair cell differentiation													biological_process											owl:Class	
GO:1903972	biolink:NamedThing	regulation of cellular response to macrophage colony-stimulating factor stimulus	Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.	got7fsn_ti	regulation of cellular response to M-CSF stimulus|regulation of cellular response to macrophage colony-stimulating factor						nc	2015-03-02T14:50:14Z						biological_process											owl:Class	
GO:1900392	biolink:NamedThing	obsolete regulation of transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-18T04:20:25Z		True				biological_process											owl:Class	
GO:1903220	biolink:NamedThing	positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.	got7fsn_ti	upregulation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of malate dehydrogenase (decarboxylating, NADP)|positive regulation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of NADP-malic enzyme activity|activation of L-malate:NADP oxidoreductase activity|up regulation of L-malate:NADP oxidoreductase activity|positive regulation of NADP-specific malate dehydrogenase activity|up regulation of malate dehydrogenase (decarboxylating, NADP)|up-regulation of 'malic' enzyme|up regulation of NADP-specific malate dehydrogenase activity|up regulation of malate dehydrogenase (NADP, decarboxylating)|upregulation of NADP-specific malic enzyme|upregulation of NADP-specific malate dehydrogenase activity|upregulation of 'malic' enzyme|positive regulation of L-malate:NADP oxidoreductase activity|up regulation of NADP-linked decarboxylating malic enzyme|up-regulation of malate dehydrogenase (NADP, decarboxylating)|upregulation of L-malate:NADP oxidoreductase activity|activation of NADP-specific malic enzyme|positive regulation of NADP-malic enzyme activity|up-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|activation of malate dehydrogenase (decarboxylating, NADP)|up-regulation of L-malate:NADP oxidoreductase activity|activation of malate dehydrogenase (NADP, decarboxylating)|positive regulation of NADP-linked decarboxylating malic enzyme|upregulation of NADP-linked decarboxylating malic enzyme|positive regulation of 'malic' enzyme|activation of 'malic' enzyme|up regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|up regulation of 'malic' enzyme|up-regulation of NADP-specific malic enzyme|up-regulation of NADP-specific malate dehydrogenase activity|up regulation of NADP-specific malic enzyme|upregulation of malate dehydrogenase (decarboxylating) (NADP+) activity|up-regulation of NADP-linked decarboxylating malic enzyme|up regulation of NADP-malic enzyme activity|positive regulation of NADP-specific malic enzyme|positive regulation of malate dehydrogenase (decarboxylating, NADP)|activation of NADP-malic enzyme activity|upregulation of malate dehydrogenase (decarboxylating, NADP)|up regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|activation of NADP-linked decarboxylating malic enzyme|up-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|activation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|activation of malate dehydrogenase (decarboxylating) (NADP+) activity|positive regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|upregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|activation of NADP-specific malate dehydrogenase activity|upregulation of NADP-malic enzyme activity						sart	2014-07-24T11:17:34Z						biological_process											owl:Class	
GO:0021866	biolink:NamedThing	obsolete asymmetric radial glial cell division in forebrain	OBSOLETE. The mitotic cell division of a radial glial cell giving rise to a radial glial cell and another cell type.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:2000887	biolink:NamedThing	glucuronoarabinoxylan catabolic process	The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan.	got7fsn_ti	glucuronoarabinoxylan catabolism						jl	2011-07-28T09:39:26Z						biological_process											owl:Class	
GO:1903219	biolink:NamedThing	negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.	got7fsn_ti	downregulation of malate dehydrogenase (NADP, decarboxylating)|negative regulation of NADP-specific malic enzyme|negative regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|negative regulation of L-malate:NADP oxidoreductase activity|down-regulation of NADP-specific malate dehydrogenase activity|down-regulation of L-malate:NADP oxidoreductase activity|down regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|downregulation of malate dehydrogenase (decarboxylating, NADP)|down-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|down regulation of NADP-linked decarboxylating malic enzyme|downregulation of 'malic' enzyme|down-regulation of 'malic' enzyme|inhibition of NADP-linked decarboxylating malic enzyme|negative regulation of NADP-linked decarboxylating malic enzyme|negative regulation of 'malic' enzyme|down-regulation of malate dehydrogenase (NADP, decarboxylating)|down regulation of malate dehydrogenase (decarboxylating, NADP)|down-regulation of malate dehydrogenase (decarboxylating, NADP)|down regulation of 'malic' enzyme|down-regulation of NADP-linked decarboxylating malic enzyme|negative regulation of NADP-malic enzyme activity|down-regulation of NADP-malic enzyme activity|inhibition of malate dehydrogenase (decarboxylating, NADP)|downregulation of NADP-specific malic enzyme|down regulation of L-malate:NADP oxidoreductase activity|down regulation of NADP-specific malic enzyme|inhibition of 'malic' enzyme|inhibition of malate dehydrogenase (NADP, decarboxylating)|downregulation of NADP-malic enzyme activity|downregulation of NADP-specific malate dehydrogenase activity|down-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|inhibition of NADP-specific malate dehydrogenase activity|negative regulation of malate dehydrogenase (NADP, decarboxylating)|downregulation of NADP-linked decarboxylating malic enzyme|downregulation of L-malate:NADP oxidoreductase activity|negative regulation of malate dehydrogenase (decarboxylating, NADP)|down regulation of NADP-malic enzyme activity|downregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down regulation of malate dehydrogenase (NADP, decarboxylating)|inhibition of NADP-specific malic enzyme|inhibition of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|inhibition of L-malate:NADP oxidoreductase activity|downregulation of malate dehydrogenase (decarboxylating) (NADP+) activity|inhibition of NADP-malic enzyme activity|down regulation of NADP-specific malate dehydrogenase activity|negative regulation of NADP-specific malate dehydrogenase activity|down-regulation of NADP-specific malic enzyme|down regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|inhibition of malate dehydrogenase (decarboxylating) (NADP+) activity						sart	2014-07-24T11:17:28Z						biological_process											owl:Class	
GO:0052013	biolink:NamedThing	obsolete catabolism by symbiont of host macromolecule	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of host macromolecule	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
CHEBI:17029	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006341	biolink:NamedThing	obsolete chromatin insulator sequence binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	chromatin insulator sequence binding			GO:0043035	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:0030383	biolink:NamedThing	obsolete host-pathogen interaction	OBSOLETE. Any interaction between a pathogen and its host organism.	got7fsn_ti	host-pathogen interaction				This term was made obsolete because more appropriate terms were created.	GO:0044403				True				biological_process											owl:Class	
GO:0005489	biolink:NamedThing	obsolete electron transporter activity	OBSOLETE. Enables the directed movement of electrons into, out of, within or between cells.	got7fsn_ti	class IV cytochrome c|electron transporter activity|cytochrome d|cytochrome c7 (triheme)|cytochrome b|respiratory chain cytochrome b6|cytochrome b5|class II cytochrome c|nonaheme cytochrome c|cytochrome c554|cytochrome c3 (tetraheme)|flavin-containing electron transporter|high-molecular-weight cytochrome c (hexadecaheme)|class I cytochrome c|class IIa cytochrome c|diheme class I cytochrome c|flavodoxin|class III cytochrome c|electron transfer carrier|monoheme class I cytochrome c|class IIb cytochrome c|Rieske iron-sulfur protein			GO:0009055	This term was made obsolete because the activity described by the definition does not exist.					True				molecular_function											owl:Class	
GO:1900061	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling	OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling.	got7fsn_ti	up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of global transcription from Pol II promoter of calcium-mediated signalling|positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|stimulation of transcription from RNA polymerase II promoter of calcium signaling|activation of global transcription from RNA polymerase II promoter of calcium signaling|positive regulation of global transcription from Pol II promoter of calcium-mediated signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter of calcium signalling|positive regulation of global transcription from Pol II promoter of calcium signalling|stimulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling|stimulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|activation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of transcription from RNA polymerase II promoter of calcium signalling|up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|upregulation of global transcription from RNA polymerase II promoter of calcium signalling|up-regulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling|positive regulation of transcription from Pol II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium signaling|upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|activation of transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of transcription from RNA polymerase II promoter of calcium signalling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling|stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of transcription from RNA polymerase II promoter of calcium signaling|activation of transcription from RNA polymerase II promoter of calcium ion signaling|upregulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of global transcription from RNA polymerase II promoter of calcium signaling|up regulation of global transcription from RNA polymerase II promoter of calcium signalling|up regulation of transcription from RNA polymerase II promoter of calcium ion signaling|activation of transcription from RNA polymerase II promoter of calcium signalling|up-regulation of global transcription from RNA polymerase II promoter of calcium signalling|up regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of transcription from RNA polymerase II promoter of calcium ion signaling|stimulation of global transcription from RNA polymerase II promoter of calcium signaling|positive regulation of transcription from Pol II promoter of calcium signalling|positive regulation of transcription from Pol II promoter of calcium ion signaling|positive regulation of global transcription from Pol II promoter of calcium ion signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|stimulation of transcription from RNA polymerase II promoter of calcium ion signaling|stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|stimulation of global transcription from RNA polymerase II promoter of calcium ion signaling|up regulation of transcription from RNA polymerase II promoter of calcium signaling|activation of transcription from RNA polymerase II promoter of calcium signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling|upregulation of global transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from RNA polymerase II promoter of calcium signaling|up-regulation of transcription from RNA polymerase II promoter of calcium signaling|positive regulation of global transcription from Pol II promoter of calcium signaling|stimulation of transcription from RNA polymerase II promoter of calcium signalling|up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|activation of global transcription from RNA polymerase II promoter of calcium ion signaling|activation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling|upregulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of transcription from Pol II promoter of calcium signaling|activation of global transcription from RNA polymerase II promoter of calcium signalling|stimulation of global transcription from RNA polymerase II promoter of calcium signalling|activation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of transcription from Pol II promoter of calcium-mediated signaling|up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|upregulation of transcription from RNA polymerase II promoter of calcium ion signaling|up regulation of global transcription from RNA polymerase II promoter of calcium ion signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from RNA polymerase II promoter of calcium signalling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling				This term was made obsolete because it represents a GO-CAM model.	GO:0019722|GO:0045944	dph	2012-01-26T01:42:53Z		True				biological_process											owl:Class	
GO:1903470	biolink:NamedThing	obsolete actomyosin contractile ring assembly involved in mitotic cell cycle	OBSOLETE. Any actomyosin contractile ring assembly that is involved in mitotic cell cycle.	got7fsn_ti	constriction ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin contractile ring formation involved in mitotic cell cycle|cytokinesis, contractile ring assembly involved in mitotic cell cycle|contractile ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin contractile ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin ring formation involved in mitotic cell cycle|cytokinesis, actomyosin ring biosynthesis involved in mitotic cell cycle				This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2014-09-23T14:06:50Z		True				biological_process											owl:Class	
GO:0150153	biolink:NamedThing	positive regulation of interleukin-17A production	Any process that activates or increases the frequency, rate or extent of interleukin-17A production.	got7fsn_ti	positive regulation of interleukin-17A biosynthetic process						bc	2019-12-11T07:45:44Z						biological_process											owl:Class	
GO:0050063	biolink:NamedThing	obsolete low-density-lipoprotein particle receptor kinase activity	OBSOLETE. Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine.	got7fsn_ti	low-density-lipoprotein receptor kinase (phosphorylating) activity|low-density-lipoprotein kinase activity|ATP:low-density-lipoprotein-L-serine O-phosphotransferase activity|ATP:low-density-lipoprotein receptor-L-serine O-phosphotransferase activity|low-density lipoprotein receptor kinase activity|STK7|[low-density lipoprotein receptor] kinase activity|low-density-lipoprotein receptor kinase activity|LDL receptor kinase activity				This term was made obsolete because it represents a specific gene product.					True		EC:2.7.11.29|MetaCyc:2.7.11.29-RXN		molecular_function											owl:Class	
GO:0100024	biolink:NamedThing	obsolete regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1901648	biolink:NamedThing	regulation of actomyosin contractile ring localization	Any process that modulates the frequency, rate or extent of actomyosin contractile ring localization.	got7fsn_ti	regulation of contractile ring localisation involved in cell cycle cytokinesis|regulation of contractile ring localization involved in cell cycle cytokinesis						vw	2012-11-19T13:42:45Z						biological_process											owl:Class	
CHEBI:57592	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903920	biolink:NamedThing	positive regulation of actin filament severing	Any process that activates or increases the frequency, rate or extent of actin filament severing.	got7fsn_ti	upregulation of actin filament severing|upregulation of F-actin severing|upregulation of actin filament severing activity|positive regulation of barbed-end actin capping/severing activity|upregulation of barbed-end actin capping/severing activity|activation of F-actin severing|activation of actin filament severing|up-regulation of actin filament severing|up-regulation of F-actin severing|up regulation of actin filament severing|positive regulation of F-actin severing|up regulation of actin filament severing activity|activation of barbed-end actin capping/severing activity|up-regulation of barbed-end actin capping/severing activity|up-regulation of actin filament severing activity|positive regulation of actin filament severing activity|up regulation of F-actin severing|activation of actin filament severing activity|up regulation of barbed-end actin capping/severing activity						als	2015-02-10T11:01:40Z						biological_process											owl:Class	
GO:1904074	biolink:NamedThing	negative regulation of trophectodermal cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation.	got7fsn_ti	down-regulation of trophectodermal cell proliferation|down-regulation of trophectoderm cell proliferation|down regulation of trophectodermal cell proliferation|inhibition of trophectodermal cell proliferation|downregulation of trophectodermal cell proliferation|inhibition of trophectoderm cell proliferation|downregulation of trophectoderm cell proliferation|down regulation of trophectoderm cell proliferation|negative regulation of trophectoderm cell proliferation						tb	2015-03-20T16:56:02Z						biological_process											owl:Class	
GO:0061465	biolink:NamedThing	obsolete plasma membrane part of hemidesmosome	OBSOLETE. The part of the plasma membrane that contributes to the structure of a hemidesmosome.	got7fsn_ti					The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM.		dph	2012-10-19T13:47:25Z		True				cellular_component											owl:Class	
GO:0052865	biolink:NamedThing	1-deoxy-D-xylulose 5-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.	got7fsn_ti	(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthesis|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate synthesis|1-deoxy-D-xylulose 5-phosphate anabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthetic process|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate anabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate formation|1-deoxy-D-xylulose 5-phosphate formation|1-deoxy-D-xylulose 5-phosphate synthesis|1-deoxy-D-xylulose 5-phosphate biosynthesis											UniPathway:UPA00064		biological_process											owl:Class	
GO:2000378	biolink:NamedThing	negative regulation of reactive oxygen species metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.	got7fsn_ti	negative regulation of ROS metabolic process|negative regulation of reactive oxygen species metabolism						mah	2011-02-11T02:06:49Z						biological_process											owl:Class	
GO:1902043	biolink:NamedThing	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.	got7fsn_ti	activation of death receptor-mediated apoptosis|up regulation of death receptor-mediated apoptosis|upregulation of extrinsic apoptotic signaling pathway via death domain receptors|activation of extrinsic apoptotic signaling pathway via death domain receptors|up-regulation of extrinsic apoptotic signaling pathway via death domain receptors|upregulation of death receptor-mediated apoptosis|positive regulation of death receptor-mediated apoptosis|up-regulation of death receptor-mediated apoptosis|up regulation of extrinsic apoptotic signaling pathway via death domain receptors						lb	2013-04-03T07:17:11Z						biological_process											owl:Class	
GO:1901279	biolink:NamedThing	D-ribose 5-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate.	got7fsn_ti	D-ribose 5-phosphate degradation|D-ribose 5-phosphate breakdown|D-ribose 5-phosphate catabolism						yaf	2012-08-17T15:00:19Z						biological_process											owl:Class	
GO:0052480	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont JA-mediated signal transduction pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0061312	biolink:NamedThing	BMP signaling pathway involved in heart development	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time.	got7fsn_ti	BMP signalling pathway involved in heart development						dph	2010-09-23T11:02:14Z						biological_process											owl:Class	
GO:0042269	biolink:NamedThing	regulation of natural killer cell mediated cytotoxicity	Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity.	got7fsn_ti	regulation of NK cell mediated cell killing|regulation of natural killer cell mediated cytolysis|regulation of natural killer-cell mediated cytolysis|regulation of NK cell mediated cytolysis|regulation of NK cell mediated cell death|regulation of NK cell mediated cytotoxicity|regulation of natural killer cell mediated cell death|regulation of natural killer cell mediated cell killing													biological_process											owl:Class	
GO:1903607	biolink:NamedThing	cytochrome c biosynthetic process	The chemical reactions and pathways resulting in the formation of cytochrome c.	got7fsn_ti	cytochrome c formation|cytochrome c synthesis|cytochrome c biosynthesis|cytochrome c anabolism						dph	2014-11-13T20:01:35Z						biological_process											owl:Class	
GO:1904064	biolink:NamedThing	positive regulation of cation transmembrane transport	Any process that activates or increases the frequency, rate or extent of cation transmembrane transport.	got7fsn_ti	up-regulation of cation transmembrane transport|activation of cation transmembrane transport|upregulation of cation transmembrane transport|up regulation of cation transmembrane transport						sl	2015-03-18T21:11:55Z						biological_process											owl:Class	
GO:0090343	biolink:NamedThing	positive regulation of cell aging	Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.	got7fsn_ti							tb	2010-06-02T10:12:37Z						biological_process											owl:Class	
GO:1900703	biolink:NamedThing	positive regulation of orcinol biosynthetic process	Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process.	got7fsn_ti	up regulation of orcinol synthesis|upregulation of orcinol anabolism|upregulation of orcinol biosynthesis|positive regulation of orcinol synthesis|up regulation of orcinol anabolism|upregulation of orcinol biosynthetic process|upregulation of orcinol formation|upregulation of orcinol synthesis|up-regulation of orcinol anabolism|up-regulation of orcinol biosynthesis|positive regulation of orcinol formation|up-regulation of orcinol synthesis|activation of orcinol anabolism|up-regulation of orcinol formation|positive regulation of orcinol anabolism|up regulation of orcinol formation|up-regulation of orcinol biosynthetic process|activation of orcinol formation|activation of orcinol biosynthetic process|positive regulation of orcinol biosynthesis|activation of orcinol biosynthesis|up regulation of orcinol biosynthesis|activation of orcinol synthesis|up regulation of orcinol biosynthetic process						di	2012-05-22T04:58:28Z						biological_process											owl:Class	
GO:0075338	biolink:NamedThing	obsolete modulation of growth or development of symbiont during interaction with host	OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	got7fsn_ti	modulation of growth or development of symbiont during interaction with host				This term was made obsolete because it contained a conjunction (or).	GO:0044145				True				biological_process											owl:Class	
GO:0016873	biolink:NamedThing	obsolete other isomerase activity	OBSOLETE. A grouping term for isomerases that cannot be more accurately categorized.	got7fsn_ti	other isomerase activity				This term was made obsolete because it was an unnecessary grouping term.	GO:0016853				True				molecular_function											owl:Class	
GO:1990980	biolink:NamedThing	obsolete copper ion transport across blood-CSF barrier	OBSOLETE. The directed movement of copper ions passing through the blood-cerebrospinal fluid barrier.	got7fsn_ti	copper ion transport across blood-cerebrospinal fluid barrier|copper ion transport across BCB				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-08-17T21:14:18Z		True				biological_process											owl:Class	
GO:0005989	biolink:NamedThing	lactose biosynthetic process	The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose.	got7fsn_ti	lactose anabolism|lactose synthesis|lactose biosynthesis|lactose formation													biological_process											owl:Class	
GO:1900481	biolink:NamedThing	negative regulation of diacylglycerol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process.	got7fsn_ti	negative regulation of diacylglycerol biosynthesis|inhibition of diacylglycerol biosynthesis|downregulation of diacylglycerol formation|downregulation of diacylglycerol anabolism|down regulation of diacylglycerol anabolism|down regulation of diacylglycerol biosynthesis|down-regulation of diacylglycerol anabolism|negative regulation of diacylglycerol anabolism|down-regulation of diacylglycerol biosynthetic process|downregulation of diacylglycerol synthesis|inhibition of diacylglycerol formation|downregulation of diacylglycerol biosynthetic process|down regulation of diacylglycerol synthesis|down regulation of diacylglycerol biosynthetic process|down-regulation of diacylglycerol biosynthesis|down regulation of diacylglycerol formation|inhibition of diacylglycerol anabolism|inhibition of diacylglycerol biosynthetic process|negative regulation of diacylglycerol formation|down-regulation of diacylglycerol synthesis|inhibition of diacylglycerol synthesis|negative regulation of diacylglycerol synthesis|down-regulation of diacylglycerol formation|downregulation of diacylglycerol biosynthesis						al	2012-05-02T10:09:09Z						biological_process											owl:Class	
GO:0051042	biolink:NamedThing	negative regulation of calcium-independent cell-cell adhesion	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.	got7fsn_ti	down-regulation of calcium-independent cell-cell adhesion|downregulation of calcium-independent cell-cell adhesion|inhibition of calcium-independent cell-cell adhesion|down regulation of calcium-independent cell-cell adhesion													biological_process											owl:Class	
GO:0042759	biolink:NamedThing	long-chain fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain fatty acid formation|long-chain fatty acid biosynthesis|long-chain fatty acid anabolism|long-chain fatty acid synthesis													biological_process											owl:Class	
GO:1900194	biolink:NamedThing	negative regulation of oocyte maturation	Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.	got7fsn_ti	downregulation of oocyte maturation|down regulation of oocyte maturation|down-regulation of oocyte maturation|inhibition of oocyte maturation						kmv	2012-03-19T09:41:27Z						biological_process											owl:Class	
GO:1904211	biolink:NamedThing	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol	Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol.	got7fsn_ti	intramembrane proteolysis involved in ERAD|membrane protein proteolysis involved in protein dislocation from ER|intramembrane cleavage of ERAD substrate|membrane protein proteolysis involved in retrograde protein transport, endoplasmic reticulum to cytosol|membrane protein proteolysis involved in protein retrotranslocation, ER to cytosol						bf	2015-05-14T15:26:44Z						biological_process											owl:Class	
GO:1903364	biolink:NamedThing	positive regulation of cellular protein catabolic process	Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process.	got7fsn_ti	upregulation of cellular protein breakdown|up-regulation of cellular protein catabolic process|activation of cellular protein breakdown|positive regulation of cellular protein degradation|activation of cellular protein degradation|up regulation of cellular protein catabolism|positive regulation of cyclin catabolic process|up-regulation of cellular protein degradation|up regulation of cellular protein degradation|up-regulation of cellular protein catabolism|activation of cellular protein catabolism|upregulation of cellular protein degradation|upregulation of cellular protein catabolism|positive regulation of cyclin catabolism|activation of cellular protein catabolic process|positive regulation of cyclin breakdown|upregulation of cellular protein catabolic process|up regulation of cellular protein breakdown|positive regulation of cellular protein catabolism|up-regulation of cellular protein breakdown|up regulation of cellular protein catabolic process|positive regulation of cellular protein breakdown|positive regulation of cyclin degradation|positive regulation of degradation of cyclin						kmv	2014-08-21T15:06:01Z			GO:2000600			biological_process											owl:Class	
GO:1905280	biolink:NamedThing	negative regulation of retrograde transport, endosome to Golgi	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi.	got7fsn_ti	downregulation of retrograde transport, endosome to Golgi|down regulation of retrograde (endosome to Golgi) transport|inhibition of retrograde transport, endosome to Golgi|down-regulation of retrograde transport, endosome to Golgi|down-regulation of retrograde (endosome to Golgi) transport|negative regulation of retrograde (endosome to Golgi) transport|inhibition of retrograde (endosome to Golgi) transport|downregulation of retrograde (endosome to Golgi) transport|down regulation of retrograde transport, endosome to Golgi						bf	2016-06-20T12:25:37Z						biological_process											owl:Class	
GO:0005054	biolink:NamedThing	obsolete peroxisome integral membrane receptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Pas20p|peroxisome integral membrane receptor				This term was made obsolete because it describes a cellular component.	GO:0038023				True				molecular_function											owl:Class	
GO:0060849	biolink:NamedThing	obsolete regulation of transcription involved in lymphatic endothelial cell fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0060838	dph	2009-08-12T11:19:14Z		True				biological_process											owl:Class	
GO:1904006	biolink:NamedThing	negative regulation of phospholipase D activity	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity.	got7fsn_ti	downregulation of phospholipase D activity|down regulation of phosphatidylcholine phosphatidohydrolase activity|downregulation of lecithinase D activity|negative regulation of lecithinase D activity|down regulation of lecithinase D activity|inhibition of phospholipase D activity|down regulation of lipophosphodiesterase II activity|negative regulation of phosphatidylcholine phosphatidohydrolase activity|down regulation of choline phosphatase activity|inhibition of lipophosphodiesterase II activity|downregulation of lipophosphodiesterase II activity|inhibition of lecithinase D activity|inhibition of choline phosphatase activity|negative regulation of lipophosphodiesterase II activity|downregulation of phosphatidylcholine phosphatidohydrolase activity|negative regulation of choline phosphatase activity|down-regulation of choline phosphatase activity|down regulation of phospholipase D activity|down-regulation of phosphatidylcholine phosphatidohydrolase activity|downregulation of choline phosphatase activity|down-regulation of phospholipase D activity|inhibition of phosphatidylcholine phosphatidohydrolase activity|down-regulation of lecithinase D activity|down-regulation of lipophosphodiesterase II activity						sl	2015-03-06T17:20:11Z						biological_process											owl:Class	
GO:1904657	biolink:NamedThing	negative regulation of sensory perception of sweet taste	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste.	got7fsn_ti	inhibition of sweet taste perception|inhibition of sensory perception of sweet taste|negative regulation of sweet taste perception|downregulation of sensory perception of sweet taste|down regulation of sensory perception of sweet taste|down-regulation of sensory perception of sweet taste|down regulation of sweet taste perception|down-regulation of sweet taste perception|downregulation of sweet taste perception						mr	2015-09-04T16:43:18Z						biological_process											owl:Class	
GO:0090026	biolink:NamedThing	positive regulation of monocyte chemotaxis	Any process that increases the frequency, rate, or extent of monocyte chemotaxis.	got7fsn_ti							tb	2009-08-03T10:18:54Z						biological_process											owl:Class	
GO:0150099	biolink:NamedThing	neuron-glial cell signaling	Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signalling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine.	got7fsn_ti	neurone-glia signalling|neuron-glial cell signalling|neuron-glia signaling|neuron-glia signalling|neurone-glial cell signaling|neurone-glial cell signalling|neurone-glia signaling						bc	2018-12-17T12:30:12Z						biological_process											owl:Class	
GO:1900973	biolink:NamedThing	positive regulation of sarcinapterin biosynthetic process	Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process.	got7fsn_ti	up-regulation of sarcinapterin formation|up regulation of sarcinapterin biosynthesis|up-regulation of sarcinapterin anabolism|upregulation of sarcinapterin synthesis|upregulation of sarcinapterin biosynthesis|positive regulation of sarcinapterin biosynthesis|up regulation of sarcinapterin synthesis|activation of sarcinapterin synthesis|upregulation of sarcinapterin biosynthetic process|positive regulation of sarcinapterin formation|up regulation of sarcinapterin formation|positive regulation of sarcinapterin synthesis|positive regulation of sarcinapterin anabolism|upregulation of sarcinapterin anabolism|upregulation of sarcinapterin formation|activation of sarcinapterin formation|activation of sarcinapterin biosynthesis|up-regulation of sarcinapterin synthesis|up regulation of sarcinapterin biosynthetic process|up regulation of sarcinapterin anabolism|up-regulation of sarcinapterin biosynthetic process|activation of sarcinapterin anabolism|activation of sarcinapterin biosynthetic process|up-regulation of sarcinapterin biosynthesis						tt	2012-06-14T04:00:14Z						biological_process											owl:Class	
GO:1900963	biolink:NamedThing	negative regulation of methanophenazine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process.	got7fsn_ti	down-regulation of methanophenazine biosynthetic process|downregulation of methanophenazine anabolism|downregulation of methanophenazine biosynthesis|down-regulation of methanophenazine anabolism|down-regulation of methanophenazine biosynthesis|inhibition of methanophenazine biosynthetic process|negative regulation of methanophenazine anabolism|down regulation of methanophenazine biosynthetic process|inhibition of methanophenazine anabolism|downregulation of methanophenazine synthesis|negative regulation of methanophenazine formation|down regulation of methanophenazine biosynthesis|inhibition of methanophenazine formation|inhibition of methanophenazine biosynthesis|down regulation of methanophenazine synthesis|negative regulation of methanophenazine synthesis|down-regulation of methanophenazine synthesis|down regulation of methanophenazine anabolism|downregulation of methanophenazine biosynthetic process|downregulation of methanophenazine formation|down-regulation of methanophenazine formation|negative regulation of methanophenazine biosynthesis|down regulation of methanophenazine formation|inhibition of methanophenazine synthesis						tt	2012-06-14T03:53:38Z						biological_process											owl:Class	
GO:0052257	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction	OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	PAMP dependent induction of innate immunity of other organism|general elicitor-dependent induction of innate immunity of other organism|pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism involved in symbiotic interaction|PAMP-dependent induction of innate immunity of other organism|pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism during symbiotic interaction|MAMP dependent induction of innate immunity of other organism|MAMP-dependent induction of innate immunity of other organism|general elicitor dependent induction of innate immunity of other organism				This term was obsoleted because it has been misused.	GO:0052034|GO:0002221|GO:0002752				True				biological_process											owl:Class	
GO:0005155	biolink:NamedThing	obsolete epidermal growth factor receptor activating ligand activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	epidermal growth factor receptor activating ligand activity|EGFR activating ligand activity|EGF receptor activating ligand activity			GO:0005154	This term was made obsolete because it represents both a biological process and a molecular function.	GO:0045741|GO:0030297				True				molecular_function											owl:Class	
GO:0099123	biolink:NamedThing	somato-dendritic dopamine secretion	The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron.	got7fsn_ti	STD DA release|somatodendritic dopamine release|STD dopamine release													biological_process											owl:Class	
GO:0039016	biolink:NamedThing	cell-cell signaling involved in pronephros development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.	got7fsn_ti	cell-cell signaling involved in pronephric kidney development|cell-cell signalling involved in pronephros development						bf	2010-07-02T10:03:16Z						biological_process											owl:Class	
GO:0051420	biolink:NamedThing	obsolete nebulette binding	OBSOLETE. Binding to nebulette, a 107 kDa protein associated with the I-Z-I complex of cardiac myofibrils. It shows a high degree of homology with skeletal muscle nebulin.	got7fsn_ti	nebulette binding			GO:0008092	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:0007011	biolink:NamedThing	obsolete regulation of cytoskeleton	OBSOLETE. Any process that modulates the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton.	got7fsn_ti	regulation of cytoskeleton				This term was made obsolete because cytoskeleton is neither a process nor a trait, so the term made no sense.	GO:0007010				True				biological_process											owl:Class	
GO:0046338	biolink:NamedThing	phosphatidylethanolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.	got7fsn_ti	phosphatidylethanolamine breakdown|phosphatidylethanolamine catabolism|phosphatidylethanolamine degradation													biological_process											owl:Class	
GO:1902204	biolink:NamedThing	positive regulation of hepatocyte growth factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.	got7fsn_ti	activation of Met signaling pathway|up-regulation of HGF receptor signaling pathway|up-regulation of HGF receptor signalling pathway|positive regulation of HGF receptor signalling pathway|upregulation of Met signaling pathway|up regulation of HGF receptor signalling pathway|up-regulation of Met signaling pathway|upregulation of hepatocyte growth factor receptor signaling pathway|activation of HGF receptor signaling pathway|up regulation of hepatocyte growth factor receptor signaling pathway|up regulation of HGF receptor signaling pathway|up regulation of Met signaling pathway|up-regulation of hepatocyte growth factor receptor signaling pathway|upregulation of HGF receptor signalling pathway|activation of hepatocyte growth factor receptor signaling pathway|positive regulation of HGF receptor signaling pathway|positive regulation of Met signaling pathway|activation of HGF receptor signalling pathway|upregulation of HGF receptor signaling pathway						lb	2013-06-10T13:20:56Z						biological_process											owl:Class	
GO:1990848	biolink:NamedThing	obsolete Positive regulation of removal of reactive oxygen species	OBSOLETE. Any process that increases the frequency, rate or extent of removal of reactive oxygen species in a cell.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-09-09T11:59:57Z		True				biological_process											owl:Class	
GO:0004987	biolink:NamedThing	obsolete kappa-opioid receptor activity	OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of kappa-opioid receptors, including high affinity for dynorphins.	got7fsn_ti	kappa-opioid receptor activity				This term was made obsolete because the receptor is defined based on its pharmacological properties.	GO:0038048				True		Wikipedia:Kappa_Opioid_receptor		molecular_function											owl:Class	
GO:1903648	biolink:NamedThing	positive regulation of chlorophyll catabolic process	Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process.	got7fsn_ti	activation of chlorophyll catabolic process|up-regulation of chlorophyll catabolic process|upregulation of chlorophyll breakdown|upregulation of chlorophyll degradation|up regulation of chlorophyll breakdown|up-regulation of chlorophyll catabolism|up-regulation of chlorophyll degradation|up regulation of chlorophyll catabolic process|up-regulation of chlorophyll breakdown|positive regulation of chlorophyll breakdown|activation of chlorophyll catabolism|up regulation of chlorophyll degradation|activation of chlorophyll breakdown|upregulation of chlorophyll catabolic process|positive regulation of chlorophyll degradation|positive regulation of chlorophyll catabolism|upregulation of chlorophyll catabolism|up regulation of chlorophyll catabolism|activation of chlorophyll degradation						tb	2014-11-22T00:18:34Z						biological_process											owl:Class	
GO:0098634	biolink:NamedThing	cell-matrix adhesion mediator activity	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the extracellular matrix.	got7fsn_ti	cell-matrix adhesion molecule|protein binding involved in cell-matrix adhesion													molecular_function											owl:Class	
GO:1904703	biolink:NamedThing	negative regulation of protein localization to adherens junction	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	got7fsn_ti	down-regulation of protein localization in cell-cell adherens junction|inhibition of protein localization in cell-cell adherens junction|down regulation of protein localization to cell-cell adherens junction|down regulation of protein localisation to cell-cell adherens junction|down-regulation of protein localization to cell-cell adherens junction|negative regulation of protein localisation to cell-cell adherens junction|downregulation of protein localization in cell-cell adherens junction|downregulation of protein localisation in cell-cell adherens junction|inhibition of protein localisation to cell-cell adherens junction|down-regulation of protein localisation to cell-cell adherens junction|down-regulation of protein localisation in cell-cell adherens junction|inhibition of protein localization to cell-cell adherens junction|negative regulation of protein localization in cell-cell adherens junction|downregulation of protein localization to cell-cell adherens junction|negative regulation of protein localisation in cell-cell adherens junction|inhibition of protein localisation in cell-cell adherens junction|downregulation of protein localisation to cell-cell adherens junction|down regulation of protein localization in cell-cell adherens junction|down regulation of protein localisation in cell-cell adherens junction						kmv	2015-10-01T15:11:56Z						biological_process											owl:Class	
GO:2000131	biolink:NamedThing	regulation of tyramine signaling pathway	Any process that modulates the frequency, rate or extent of tyramine signaling pathway.	got7fsn_ti	regulation of tyramine signalling pathway						mah	2010-09-29T09:31:56Z						biological_process											owl:Class	
GO:1900105	biolink:NamedThing	negative regulation of hyaluranon cable assembly	Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly.	got7fsn_ti	downregulation of HA cable assembly|inhibition of hyaluranon cable assembly|negative regulation of HA cable assembly|down-regulation of hyaluranon cable assembly|down regulation of hyaluranon cable assembly|down regulation of HA cable assembly|down-regulation of HA cable assembly|downregulation of hyaluranon cable assembly|inhibition of HA cable assembly						yaf	2012-02-16T01:00:50Z						biological_process											owl:Class	
GO:0072421	biolink:NamedThing	obsolete detection of DNA damage stimulus involved in DNA damage checkpoint	OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a DNA damage checkpoint.	got7fsn_ti	DNA damage checkpoint sensor process|sensing involved in DNA damage checkpoint|DNA damage checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:16:04Z		True				biological_process											owl:Class	
GO:0032761	biolink:NamedThing	positive regulation of lymphotoxin A production	Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production.	got7fsn_ti	positive regulation of TNF-beta production|stimulation of lymphotoxin A production|up-regulation of lymphotoxin A production|positive regulation of lymphotoxin-alpha production|activation of lymphotoxin A production|upregulation of lymphotoxin A production|positive regulation of LTA production|positive regulation of lymphotoxin A biosynthetic process|positive regulation of tumor necrosis factor-beta production|up regulation of lymphotoxin A production										GO:0043017			biological_process											owl:Class	
GO:0042619	biolink:NamedThing	poly-hydroxybutyrate biosynthetic process	The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.	got7fsn_ti	poly-hydroxybutyrate synthesis|PHB biosynthetic process|poly-hydroxybutyrate anabolism|poly-hydroxybutyrate formation|PHB biosynthesis|poly-hydroxybutyrate biosynthesis													biological_process											owl:Class	
GO:0004276	biolink:NamedThing	obsolete furin activity	OBSOLETE. Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors.	got7fsn_ti	paired basic amino acid cleaving enzyme|prohormone convertase activity|SPC3|furin activity|PACE|paired basic amino acid converting enzyme|paired basic amino acid residue cleaving enzyme activity|serine proteinase PACE|dibasic processing enzyme activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0098722	biolink:NamedThing	asymmetric stem cell division	Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.	got7fsn_ti														biological_process											owl:Class	
GO:1905395	biolink:NamedThing	response to flavonoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.	got7fsn_ti							sl	2016-08-24T15:00:54Z						biological_process											owl:Class	
GO:0014917	biolink:NamedThing	obsolete positive regulation of diuresis by pressure natriuresis	OBSOLETE. The process in which pressure natriuresis increases the rate of diuresis.	got7fsn_ti	positive regulation of diuresis by pressure natriuresis			GO:0035818	This term was made obsolete because its definition was inaccurate.					True				biological_process											owl:Class	
GO:0090033	biolink:NamedThing	positive regulation of filamentous growth	Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.	got7fsn_ti							tb	2009-08-03T11:04:21Z						biological_process											owl:Class	
GO:1900645	biolink:NamedThing	positive regulation of chanoclavine-I biosynthetic process	Any process that activates or increases the frequency, rate or extent of chanoclavine-I biosynthetic process.	got7fsn_ti	positive regulation of chanoclavine-I anabolism|positive regulation of chanoclavine-I formation|positive regulation of chanoclavine-I synthesis|upregulation of chanoclavine-I formation|activation of chanoclavine-I anabolism|up-regulation of chanoclavine-I synthesis|up-regulation of chanoclavine-I anabolism|activation of chanoclavine-I biosynthetic process|up-regulation of chanoclavine-I biosynthetic process|upregulation of chanoclavine-I biosynthetic process|up regulation of chanoclavine-I formation|upregulation of chanoclavine-I synthesis|upregulation of chanoclavine-I biosynthesis|up regulation of chanoclavine-I synthesis|up regulation of chanoclavine-I biosynthesis|activation of chanoclavine-I formation|up regulation of chanoclavine-I anabolism|up-regulation of chanoclavine-I biosynthesis|upregulation of chanoclavine-I anabolism|up-regulation of chanoclavine-I formation|positive regulation of chanoclavine-I biosynthesis|activation of chanoclavine-I biosynthesis|up regulation of chanoclavine-I biosynthetic process|activation of chanoclavine-I synthesis						di	2012-05-22T04:03:38Z						biological_process											owl:Class	
GO:0018901	biolink:NamedThing	2,4-dichlorophenoxyacetic acid metabolic process	The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.	got7fsn_ti	2,4-dichlorophenoxyacetic acid metabolism|2,4-D metabolic process|2,4-D metabolism											UM-BBD_pathwayID:2,4-d		biological_process											owl:Class	
GO:0052488	biolink:NamedThing	obsolete negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	suppression of MAMP-induced symbiont innate immunity|negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity|suppression of MAMP induced symbiont innate immunity|suppression of general elicitor induced symbiont innate immunity|suppression of PAMP-induced symbiont innate immunity|suppression of PAMP induced symbiont innate immunity|suppression of pathogen-associated molecular pattern-induced symbiont innate immunity|suppression of general elicitor-induced symbiont innate immunity				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0035705	biolink:NamedThing	T-helper 17 cell chemotaxis	The directed movement of a T-helper 17 cell in response to an external stimulus.	got7fsn_ti	Th17 cell chemotaxis						bf	2011-03-02T02:35:16Z						biological_process											owl:Class	
GO:1902575	biolink:NamedThing	protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly	Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly.	got7fsn_ti	protein localization to cell division site involved in cytokinesis, actomyosin ring biosynthesis|protein localization to cell division site involved in constriction ring assembly|protein localisation to cell division site involved in contractile ring assembly|protein localisation to cell division site involved in cytokinesis, actomyosin ring biosynthesis|protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring formation|protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring assembly|protein localization to cell division site involved in cytokinesis, actomyosin ring formation|protein localization to cell division site involved in cytokinesis, contractile ring assembly|protein localization to cell division site involved in cytokinesis, actomyosin contractile ring formation|protein localisation to cell division site involved in cytokinesis, actomyosin ring formation|protein localisation to cell division site involved in cytokinesis, contractile ring assembly|protein localisation to cell division site involved in constriction ring assembly|protein localization to cell division site involved in contractile ring assembly						bf	2013-12-16T10:42:25Z						biological_process											owl:Class	
GO:0046634	biolink:NamedThing	regulation of alpha-beta T cell activation	Any process that modulates the frequency, rate or extent of alpha-beta T cell activation.	got7fsn_ti	regulation of alpha-beta T-cell activation|regulation of alpha-beta T lymphocyte activation|regulation of alpha-beta T-lymphocyte activation													biological_process											owl:Class	
GO:1900302	biolink:NamedThing	positive regulation of laminarabiose transport	Any process that activates or increases the frequency, rate or extent of laminarabiose transport.	got7fsn_ti	up-regulation of laminarabiose transport|up regulation of laminarabiose transport|activation of laminarabiose transport|upregulation of laminarabiose transport						tt	2012-04-05T07:57:37Z						biological_process											owl:Class	
GO:0060905	biolink:NamedThing	regulation of induction of conjugation upon nitrogen starvation	Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.	got7fsn_ti							dph	2009-08-14T01:17:50Z						biological_process											owl:Class	
GO:1902944	biolink:NamedThing	aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process.	got7fsn_ti	aspartic protease activity involved in APP catabolism|aspartic endopeptidase activity involved in amyloid precursor protein catabolism|carboxyl protease activity involved in APP catabolic process|carboxyl protease activity involved in amyloid precursor protein breakdown|aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|aspartate protease activity involved in amyloid precursor protein catabolism|carboxyl protease activity involved in amyloid precursor protein degradation|aspartic endopeptidase activity involved in APP catabolic process|carboxyl protease activity involved in APP catabolism|aspartyl protease activity involved in APP catabolic process|aspartic protease activity involved in APP catabolic process|aspartyl protease activity involved in APP catabolism|aspartic-type endopeptidase activity involved in APP catabolism|aspartic endopeptidase activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in amyloid precursor protein degradation|aspartic endopeptidase activity involved in amyloid precursor protein degradation|aspartyl protease activity involved in amyloid precursor protein catabolic process|aspartic protease activity involved in amyloid precursor protein catabolic process|aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|carboxyl protease activity involved in amyloid precursor protein catabolic process|aspartate protease activity involved in amyloid precursor protein degradation|aspartyl protease activity involved in amyloid precursor protein catabolism|carboxyl protease activity involved in amyloid precursor protein catabolism|aspartic endopeptidase activity involved in APP catabolism|aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|aspartate protease activity involved in amyloid precursor protein catabolic process|aspartic protease activity involved in amyloid precursor protein breakdown|aspartic protease activity involved in amyloid precursor protein catabolism|aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|aspartic-type endopeptidase activity involved in APP catabolic process|aspartate protease activity involved in APP catabolic process|aspartate protease activity involved in amyloid precursor protein breakdown|aspartate protease activity involved in APP catabolism|aspartic protease activity involved in amyloid precursor protein degradation						sjp	2014-05-02T07:59:42Z						molecular_function											owl:Class	
GO:0045784	biolink:NamedThing	obsolete positive regulation of calcium in ER	OBSOLETE. Any process that increases the concentration of calcium in the ER.	got7fsn_ti	positive regulation of calcium in ER				This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport').	GO:0005783|GO:0006874				True				biological_process											owl:Class	
GO:0045593	biolink:NamedThing	negative regulation of cumulus cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation.	got7fsn_ti	inhibition of cumulus cell differentiation|down-regulation of cumulus cell differentiation|downregulation of cumulus cell differentiation|negative regulation of ovarian cumulus cell differentiation|down regulation of cumulus cell differentiation													biological_process											owl:Class	
GO:1901225	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter involved in heart development	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development.	got7fsn_ti	down-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in dorsal vessel development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in heart development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of global transcription regulation from Pol II promoter involved in heart development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|down-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|inhibition of regulation of global transcription from Pol II promoter involved in cardiac development|inhibition of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|inhibition of global transcription regulation from Pol II promoter involved in dorsal vessel development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|negative regulation of global transcription regulation from Pol II promoter involved in cardiac development|down-regulation of global transcription regulation from Pol II promoter involved in heart development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|down regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of regulation of transcription from Pol II promoter involved in heart development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|inhibition of regulation of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in heart development|inhibition of regulation of transcription from Pol II promoter involved in heart development|downregulation of regulation of transcription from Pol II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of regulation of transcription from Pol II promoter involved in dorsal vessel development|down regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|down-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of regulation of global transcription from Pol II promoter involved in heart development|down-regulation of regulation of transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of global transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|negative regulation of regulation of transcription from Pol II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|downregulation of regulation of global transcription from Pol II promoter involved in cardiac development|down regulation of regulation of global transcription from Pol II promoter involved in heart development|downregulation of regulation of global transcription from Pol II promoter involved in heart development|down-regulation of global transcription regulation from Pol II promoter involved in cardiac development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|downregulation of regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from Pol II promoter involved in heart development|down-regulation of regulation of global transcription from Pol II promoter involved in cardiac development|downregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|inhibition of global transcription regulation from Pol II promoter involved in cardiac development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|downregulation of regulation of transcription from Pol II promoter involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of global transcription regulation from Pol II promoter involved in cardiac development|negative regulation of regulation of transcription from Pol II promoter involved in heart development|downregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of regulation of transcription from Pol II promoter involved in cardiac development|downregulation of global transcription regulation from Pol II promoter involved in cardiac development|down regulation of regulation of transcription from Pol II promoter involved in cardiac development|downregulation of global transcription regulation from Pol II promoter involved in heart development|negative regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|downregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|negative regulation of transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of global transcription from Pol II promoter involved in cardiac development|inhibition of global transcription regulation from Pol II promoter involved in heart development|negative regulation of regulation of global transcription from Pol II promoter involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of global transcription regulation from Pol II promoter involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development				This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0007507|GO:0000122	rl	2012-08-07T07:04:07Z		True				biological_process											owl:Class	
GO:0010778	biolink:NamedThing	meiotic DNA repair synthesis involved in reciprocal meiotic recombination	The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti														biological_process											owl:Class	
GO:0033090	biolink:NamedThing	positive regulation of extrathymic T cell differentiation	Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation.	got7fsn_ti	positive regulation of extrathymic T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0036194	biolink:NamedThing	muscle cell projection	A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.	got7fsn_ti	myopodia|myocyte projection|muscle arm						bf	2012-04-20T10:20:47Z						cellular_component											owl:Class	
GO:0004428	biolink:NamedThing	obsolete inositol or phosphatidylinositol kinase activity	OBSOLETE. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.	got7fsn_ti	inositol/phosphatidylinositol kinase activity|inositol or phosphatidylinositol kinase activity				This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.	GO:0016307|GO:0019140|GO:0052742|GO:0052813				True				molecular_function											owl:Class	
GO:0003695	biolink:NamedThing	obsolete random coil DNA binding	OBSOLETE. Binding to DNA in a random coil configuration.	got7fsn_ti	random coil binding	https://github.com/geneontology/go-ontology/issues/18879			This term was obsoleted because the definition was not clear enough as to what is directing specificity of the binding to the DNA.					True	GO:0016017			molecular_function											owl:Class	
GO:0060263	biolink:NamedThing	regulation of respiratory burst	Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	got7fsn_ti														biological_process											owl:Class	
GO:1902913	biolink:NamedThing	positive regulation of neuroepithelial cell differentiation	Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation.	got7fsn_ti	activation of neuroepithelial cell differentiation|upregulation of neuroepithelial cell differentiation|up regulation of neuroepithelial cell differentiation|up-regulation of neuroepithelial cell differentiation						mr	2014-04-18T21:06:42Z						biological_process											owl:Class	
GO:0097053	biolink:NamedThing	L-kynurenine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).	got7fsn_ti	L-kynurenine catabolism|L-kynurenine breakdown|L-kynurenine degradation						pr	2011-05-24T03:30:58Z						biological_process											owl:Class	
GO:0045358	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070485	biolink:NamedThing	dehydro-D-arabinono-1,4-lactone biosynthetic process	The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.	got7fsn_ti	dehydro-D-arabinono-1,4-lactone formation|dehydro-D-arabinono-1,4-lactone synthesis|dehydro-D-arabinono-1,4-lactone biosynthesis|dehydro-D-arabinono-1,4-lactone anabolism													biological_process											owl:Class	
GO:0009692	biolink:NamedThing	ethylene metabolic process	The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.	got7fsn_ti	ethene metabolism|ethene metabolic process|ethylene metabolism													biological_process											owl:Class	
GO:1900188	biolink:NamedThing	negative regulation of cell adhesion involved in single-species biofilm formation	Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.	got7fsn_ti	down-regulation of cell adhesion involved in single-species biofilm formation|downregulation of cell adhesion involved in single-species biofilm formation|down-regulation of cell adhesion during single-species biofilm formation|inhibition of cell adhesion during single-species biofilm formation|negative regulation of cell adhesion during single-species biofilm formation|down regulation of cell adhesion during single-species biofilm formation|inhibition of cell adhesion involved in single-species biofilm formation|down regulation of cell adhesion involved in single-species biofilm formation|downregulation of cell adhesion during single-species biofilm formation						di	2012-03-19T12:38:54Z						biological_process											owl:Class	
GO:0015262	biolink:NamedThing	obsolete taurine channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	taurine channel activity				This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True				molecular_function											owl:Class	
GO:1903297	biolink:NamedThing	regulation of hypoxia-induced intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.	got7fsn_ti	regulation of intrinsic apoptotic signaling pathway in response to hypoxia|regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway|regulation of hypoxia-induced apoptosis						bf	2014-08-14T14:47:48Z						biological_process											owl:Class	
GO:1905545	biolink:NamedThing	obsolete negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron.	got7fsn_ti	negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2016-10-11T16:15:05Z		True				biological_process											owl:Class	
GO:0090285	biolink:NamedThing	negative regulation of protein glycosylation in Golgi	Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.	got7fsn_ti	negative regulation of protein amino acid glycosylation in Golgi						tb	2010-02-18T02:43:55Z						biological_process											owl:Class	
GO:0046301	biolink:NamedThing	obsolete 2-chloro-N-isopropylacetanilide biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.	got7fsn_ti	2-chloro-N-isopropylacetanilide formation|2-chloro-N-isopropylacetanilide anabolism|2-chloro-N-isopropylacetanilide biosynthesis|2-chloro-N-isopropylacetanilide biosynthetic process|2-chloro-N-isopropylacetanilide synthesis			GO:0018889	This term was made obsolete because 2-chloro-N-isopropylacetanilide is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:2000784	biolink:NamedThing	positive regulation of establishment of cell polarity regulating cell shape	Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape.	got7fsn_ti							mah	2011-06-23T12:17:48Z						biological_process											owl:Class	
GO:0021777	biolink:NamedThing	obsolete BMP signaling pathway involved in spinal cord association neuron specification	OBSOLETE. A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to its commitment to an association neuron fate.	got7fsn_ti	BMP signalling pathway involved in spinal cord association neuron specification|bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification				The reason for obsoletion is that this term represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1903176	biolink:NamedThing	regulation of tyrosine 3-monooxygenase activity	Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity.	got7fsn_ti	regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|regulation of tyrosine hydroxylase activity|regulation of tyrosine 3-hydroxylase activity|regulation of L-tyrosine hydroxylase activity						bf	2014-07-14T10:39:09Z						biological_process											owl:Class	
GO:2001265	biolink:NamedThing	positive regulation of C-C chemokine binding	Any process that activates or increases the frequency, rate or extent of C-C chemokine binding.	got7fsn_ti							yaf	2011-12-09T01:14:07Z						biological_process											owl:Class	
GO:0046771	biolink:NamedThing	viral budding from inner nuclear membrane	The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope.	got7fsn_ti	viral budding from inner nuclear membrane during viral capsid envelopment|inner nuclear membrane viral budding during viral capsid envelopment|virus budding from inner nuclear membrane during viral capsid envelopment|viral budding from inner nuclear membrane by viral capsid envelopment|virus budding from inner nuclear membrane by viral capsid envelopment	https://github.com/geneontology/go-ontology/issues/20782												biological_process											owl:Class	
GO:0044336	biolink:NamedThing	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the negative regulation of apoptotic process.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis|canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process|canonical Wnt receptor signalling pathway involved in negative regulation of apoptosis						jl	2010-08-20T03:07:53Z						biological_process											owl:Class	
GO:0052438	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont callose deposition	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont callose deposition				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0010336	biolink:NamedThing	gibberellic acid homeostasis	Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation.	got7fsn_ti	gibberellin homeostasis													biological_process											owl:Class	
GO:1900516	biolink:NamedThing	negative regulation of xylose catabolic process to ethanol	Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol.	got7fsn_ti	inhibition of xylose catabolism to ethanol|down-regulation of xylose catabolic process to ethanol|negative regulation of xylose catabolism to ethanol|inhibition of xylose catabolic process to ethanol|down regulation of xylose catabolic process to ethanol|downregulation of xylose catabolic process to ethanol|downregulation of xylose catabolism to ethanol|down regulation of xylose catabolism to ethanol|down-regulation of xylose catabolism to ethanol						tt	2012-05-02T04:09:17Z						biological_process											owl:Class	
GO:2000588	biolink:NamedThing	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.	got7fsn_ti	positive regulation of betaPDGF receptor signaling pathway|positive regulation of PDGFR-beta signaling pathway|positive regulation of platelet-derived growth factor receptor-beta signalling pathway|positive regulation of PDGF receptor-beta signaling pathway						bf	2011-04-07T03:27:58Z						biological_process											owl:Class	
GO:1900823	biolink:NamedThing	negative regulation of ergot alkaloid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process.	got7fsn_ti	down-regulation of ergot alkaloid biosynthetic process|inhibition of ergot alkaloid synthesis|downregulation of ergot alkaloid formation|downregulation of ergot alkaloid biosynthetic process|downregulation of ergot alkaloid synthesis|down regulation of ergot alkaloid biosynthetic process|inhibition of ergot alkaloid biosynthesis|down-regulation of ergot alkaloid biosynthesis|down-regulation of ergot alkaloid anabolism|negative regulation of ergot alkaloid anabolism|downregulation of ergot alkaloid biosynthesis|down regulation of ergot alkaloid synthesis|downregulation of ergot alkaloid anabolism|inhibition of ergot alkaloid anabolism|negative regulation of ergot alkaloid formation|down regulation of ergot alkaloid formation|inhibition of ergot alkaloid biosynthetic process|down regulation of ergot alkaloid anabolism|inhibition of ergot alkaloid formation|down-regulation of ergot alkaloid synthesis|down regulation of ergot alkaloid biosynthesis|negative regulation of ergot alkaloid biosynthesis|negative regulation of ergot alkaloid synthesis|down-regulation of ergot alkaloid formation						di	2012-06-04T11:12:54Z						biological_process											owl:Class	
GO:1903852	biolink:NamedThing	positive regulation of cristae formation	Any process that activates or increases the frequency, rate or extent of cristae formation.	got7fsn_ti	activation of cristae formation|up-regulation of cristae formation|up regulation of cristae formation|upregulation of cristae formation				AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype		pad	2015-01-27T09:42:42Z						biological_process											owl:Class	
GO:0015910	biolink:NamedThing	long-chain fatty acid import into peroxisome	The directed movement of long-chain fatty acids into a peroxisome. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	peroxisomal long-chain fatty acid import|peroxisomal long-chain fatty acid uptake													biological_process											owl:Class	
GO:1904761	biolink:NamedThing	negative regulation of myofibroblast differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation.	got7fsn_ti	down-regulation of myofibroblast differentiation|down-regulation of myofibroblast cell differentiation|inhibition of myofibroblast cell differentiation|downregulation of myofibroblast differentiation|downregulation of myofibroblast cell differentiation|down regulation of myofibroblast differentiation|down regulation of myofibroblast cell differentiation|inhibition of myofibroblast differentiation|negative regulation of myofibroblast cell differentiation						rph	2015-10-23T12:15:11Z						biological_process											owl:Class	
GO:1901755	biolink:NamedThing	vitamin D3 biosynthetic process	The chemical reactions and pathways resulting in the formation of vitamin D3.	got7fsn_ti	calciol anabolism|cholecalciferol biosynthetic process|cholecalciferol biosynthesis|vitamin D3 synthesis|calciol biosynthesis|calciol biosynthetic process|calciol synthesis|vitamin D3 formation|calciol formation|vitamin D3 anabolism|vitamin D3 biosynthesis						yaf	2013-01-14T11:11:09Z						biological_process											owl:Class	
GO:0045668	biolink:NamedThing	negative regulation of osteoblast differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.	got7fsn_ti	down regulation of osteoblast differentiation|inhibition of osteoblast differentiation|downregulation of osteoblast differentiation|down-regulation of osteoblast differentiation													biological_process											owl:Class	
GO:1901613	biolink:NamedThing	negative regulation of terminal button organization	Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization.	got7fsn_ti	down regulation of bouton organization|downregulation of bouton organization|downregulation of presynaptic bouton organization|downregulation of terminal button organization|negative regulation of terminal button organisation|negative regulation of presynaptic bouton organization|down-regulation of bouton organization|down-regulation of synaptic bouton organization|down regulation of terminal button organisation|down-regulation of terminal button organization|inhibition of presynaptic bouton organization|negative regulation of synaptic bouton organization|downregulation of terminal button organisation|negative regulation of terminal bouton organization|downregulation of terminal bouton organization|inhibition of synaptic bouton organization|inhibition of terminal bouton organization|down regulation of terminal bouton organization|down regulation of presynaptic bouton organization|down-regulation of presynaptic bouton organization|downregulation of synaptic bouton organization|down regulation of terminal button organization|inhibition of bouton organization|inhibition of terminal button organisation|inhibition of terminal button organization|down regulation of synaptic bouton organization|negative regulation of bouton organization|down-regulation of terminal button organisation|down-regulation of terminal bouton organization						lb	2012-11-13T10:40:51Z						biological_process											owl:Class	
GO:1904894	biolink:NamedThing	positive regulation of receptor signaling pathway via STAT	Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.	got7fsn_ti	upregulation of kinase activated-STAT cascade|upregulation of STAT cascade|up-regulation of kinase activated-STAT cascade|positive regulation of kinase activated-STAT cascade|up-regulation of STAT signalling pathway|positive regulation of STAT signalling pathway|up regulation of STAT cascade|up regulation of kinase activated-STAT cascade|activation of STAT cascade|upregulation of kinase-STAT cascade|upregulation of STAT signalling pathway|up regulation of STAT signalling pathway|up-regulation of STAT cascade|activation of STAT signalling pathway|activation of kinase activated-STAT cascade|activation of kinase-STAT cascade|up-regulation of kinase-STAT cascade|up regulation of kinase-STAT cascade|positive regulation of kinase-STAT cascade						pr	2016-01-08T08:14:48Z						biological_process											owl:Class	
GO:0019089	biolink:NamedThing	obsolete transmission of virus	OBSOLETE. The transfer of virions in order to create new infection.	got7fsn_ti	viral transmission				This term was obsoleted because it did not represent a specific process, but represented the life cycle of a virus.					True				biological_process											owl:Class	
GO:0044047	biolink:NamedThing	obsolete interaction with host via protein secreted by type I secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type I secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0060965	biolink:NamedThing	negative regulation of gene silencing by miRNA	Any process that decreases the rate, frequency, or extent of gene silencing by miRNA.	got7fsn_ti	negative regulation of gene silencing by microRNA						dph	2009-10-05T03:14:14Z						biological_process											owl:Class	
GO:1905116	biolink:NamedThing	positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.	got7fsn_ti	up-regulation of lateral attachment of mitotic spindle microtubules to kinetochore|activation of lateral attachment of mitotic spindle microtubules to kinetochore|upregulation of lateral attachment of mitotic spindle microtubules to kinetochore|up regulation of lateral attachment of mitotic spindle microtubules to kinetochore						al	2016-04-07T14:25:34Z						biological_process											owl:Class	
GO:0071411	biolink:NamedThing	cellular response to fluoxetine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-14T03:09:58Z						biological_process											owl:Class	
GO:0034309	biolink:NamedThing	primary alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.	got7fsn_ti	monohydric alcohol biosynthetic process|primary alcohol formation|primary alcohol anabolism|primary alcohol synthesis|primary alcohol biosynthesis													biological_process											owl:Class	
GO:1904041	biolink:NamedThing	regulation of cystathionine beta-synthase activity	Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity.	got7fsn_ti	regulation of serine sulfhydrase activity|regulation of L-serine hydro-lyase (adding homocysteine)|regulation of beta-thionase activity|regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|regulation of methylcysteine synthase activity|regulation of serine sulfhydrylase activity						hal	2015-03-16T15:52:41Z						biological_process											owl:Class	
GO:1904112	biolink:NamedThing	obsolete positive regulation of plus-end directed microfilament motor activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of plus-end directed microfilament motor activity.	got7fsn_ti	upregulation of plus-end directed microfilament motor activity|up regulation of plus-end directed actin filament motor activity|upregulation of plus-end directed actin filament motor activity|positive regulation of plus-end directed actin filament motor activity|upregulation of plus-end directed actin-filament motor activity|activation of plus-end directed microfilament motor activity|upregulation of barbed-end directed actin-filament motor activity|up-regulation of plus-end directed actin filament motor activity|up-regulation of plus-end directed microfilament motor activity|up-regulation of barbed-end directed actin-filament motor activity|activation of barbed-end directed actin-filament motor activity|up regulation of plus-end directed microfilament motor activity|positive regulation of plus-end directed actin-filament motor activity|activation of plus-end directed actin-filament motor activity|activation of plus-end directed actin filament motor activity|positive regulation of barbed-end directed actin-filament motor activity|up-regulation of plus-end directed actin-filament motor activity|up regulation of plus-end directed actin-filament motor activity|up regulation of barbed-end directed actin-filament motor activity	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140659	kmv	2015-04-03T18:28:35Z		True				biological_process											owl:Class	
GO:0046195	biolink:NamedThing	obsolete 4-nitrophenol biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.	got7fsn_ti	4-nitrophenol synthesis|4-nitrophenol biosynthesis|4-nitrophenol anabolism|4-nitrophenol biosynthetic process|4-nitrophenol formation			GO:0018960	This term was made obsolete because 4-nitrophenol is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1901471	biolink:NamedThing	positive regulation of syringal lignin catabolic process	Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process.	got7fsn_ti	up regulation of syringal lignin catabolism|positive regulation of syringal lignin breakdown|up regulation of syringal lignin breakdown|up regulation of syringal lignin catabolic process|activation of syringal lignin catabolism|positive regulation of syringal lignin degradation|activation of syringal lignin breakdown|up regulation of S-lignin catabolic process|upregulation of syringal lignin catabolism|upregulation of syringal lignin catabolic process|up-regulation of syringal lignin catabolic process|activation of syringal lignin catabolic process|positive regulation of S-lignin catabolic process|upregulation of syringal lignin breakdown|activation of syringal lignin degradation|up-regulation of syringal lignin degradation|up-regulation of S-lignin catabolic process|up-regulation of syringal lignin catabolism|up regulation of syringal lignin degradation|upregulation of syringal lignin degradation|up-regulation of syringal lignin breakdown|positive regulation of syringal lignin catabolism|upregulation of S-lignin catabolic process|activation of S-lignin catabolic process						tt	2012-10-02T14:42:39Z						biological_process											owl:Class	
GO:1904192	biolink:NamedThing	regulation of cholangiocyte apoptotic process	Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process.	got7fsn_ti	regulation of cholangiocyte apoptosis|regulation of epithelial cell of bile duct apoptosis|regulation of epithelial cell of bile duct apoptotic process						sl	2015-05-06T15:25:48Z						biological_process											owl:Class	
GO:1905012	biolink:NamedThing	regulation of 'de novo' NAD biosynthetic process from tryptophan	Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.	got7fsn_ti	regulation of de novo NAD biosynthetic process from tryptophan						bf	2016-03-03T10:00:50Z						biological_process											owl:Class	
GO:0008975	biolink:NamedThing	obsolete pitrilysin activity	OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.	got7fsn_ti	Escherichia coli protease III|PTR|protease III activity|pitrilysin activity|proteinase Pi|protease Pi activity|Escherichia coli metalloproteinase Pi			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:2000563	biolink:NamedThing	positive regulation of CD4-positive, alpha-beta T cell proliferation	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.	got7fsn_ti							ebc	2011-04-03T09:01:15Z						biological_process											owl:Class	
GO:1902035	biolink:NamedThing	positive regulation of hematopoietic stem cell proliferation	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.	got7fsn_ti	up regulation of hemopoietic stem cell proliferation|upregulation of hematopoietic stem cell proliferation|positive regulation of hemopoietic stem cell proliferation|activation of hemopoietic stem cell proliferation|upregulation of hemopoietic stem cell proliferation|activation of hematopoietic stem cell proliferation|up regulation of hematopoietic stem cell proliferation|up-regulation of hemopoietic stem cell proliferation|up-regulation of hematopoietic stem cell proliferation						ss	2013-04-02T05:13:31Z						biological_process											owl:Class	
GO:1903615	biolink:NamedThing	positive regulation of protein tyrosine phosphatase activity	Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity.	got7fsn_ti	up-regulation of protein-tyrosine-phosphate phosphohydrolase activity|upregulation of phosphotyrosine phosphatase activity|activation of protein tyrosine phosphatase activity|activation of [phosphotyrosine]protein phosphatase activity|activation of protein phosphotyrosine phosphatase activity|activation of tyrosine O-phosphate phosphatase activity|activation of phosphotyrosylprotein phosphatase activity|positive regulation of phosphotyrosine protein phosphatase activity|upregulation of protein-tyrosine-phosphate phosphohydrolase activity|upregulation of PPT-phosphatase activity|positive regulation of phosphotyrosine histone phosphatase activity|activation of protein-tyrosine-phosphate phosphohydrolase activity|upregulation of phosphotyrosine histone phosphatase activity|up regulation of [phosphotyrosine]protein phosphatase activity|upregulation of protein phosphotyrosine phosphatase activity|positive regulation of PTPase activity|activation of phosphotyrosine phosphatase activity|positive regulation of tyrosine O-phosphate phosphatase activity|upregulation of protein tyrosine phosphatase activity|up regulation of PPT-phosphatase activity|up regulation of tyrosylprotein phosphatase activity|positive regulation of tyrosylprotein phosphatase activity|activation of PPT-phosphatase activity|activation of PTP-phosphatase activity|positive regulation of phosphotyrosine phosphatase activity|up regulation of phosphotyrosylprotein phosphatase activity|upregulation of PTP-phosphatase activity|upregulation of phosphotyrosylprotein phosphatase activity|positive regulation of protein-tyrosine-phosphatase activity|up regulation of phosphotyrosine histone phosphatase activity|up regulation of phosphotyrosine phosphatase activity|up regulation of protein-tyrosine-phosphatase activity|up-regulation of phosphotyrosine protein phosphatase activity|up-regulation of PPT-phosphatase activity|up-regulation of protein phosphotyrosine phosphatase activity|up-regulation of protein tyrosine phosphatase activity|up-regulation of phosphoprotein phosphatase (phosphotyrosine) activity|up regulation of tyrosine O-phosphate phosphatase activity|positive regulation of PPT-phosphatase activity|up-regulation of tyrosine O-phosphate phosphatase activity|up-regulation of PTPase activity|up-regulation of protein-tyrosine-phosphatase activity|positive regulation of protein phosphotyrosine phosphatase activity|activation of phosphoprotein phosphatase (phosphotyrosine) activity|up-regulation of [phosphotyrosine]protein phosphatase activity|up-regulation of phosphotyrosine histone phosphatase activity|upregulation of [phosphotyrosine]protein phosphatase activity|positive regulation of [phosphotyrosine]protein phosphatase activity|activation of tyrosylprotein phosphatase activity|up regulation of protein tyrosine phosphatase activity|positive regulation of protein-tyrosine-phosphate phosphohydrolase activity|positive regulation of phosphotyrosylprotein phosphatase activity|upregulation of PTPase activity|up regulation of PTPase activity|activation of PTPase activity|positive regulation of phosphoprotein phosphatase (phosphotyrosine) activity|upregulation of tyrosylprotein phosphatase activity|up regulation of phosphotyrosine protein phosphatase activity|activation of phosphotyrosine protein phosphatase activity|up regulation of protein-tyrosine-phosphate phosphohydrolase activity|up-regulation of PTP-phosphatase activity|positive regulation of PTP-phosphatase activity|upregulation of phosphotyrosine protein phosphatase activity|up regulation of phosphoprotein phosphatase (phosphotyrosine) activity|activation of protein-tyrosine-phosphatase activity|up-regulation of phosphotyrosine phosphatase activity|up regulation of protein phosphotyrosine phosphatase activity|upregulation of tyrosine O-phosphate phosphatase activity|upregulation of phosphoprotein phosphatase (phosphotyrosine) activity|up-regulation of tyrosylprotein phosphatase activity|upregulation of protein-tyrosine-phosphatase activity|up regulation of PTP-phosphatase activity|activation of phosphotyrosine histone phosphatase activity|up-regulation of phosphotyrosylprotein phosphatase activity						sl	2014-11-18T01:11:55Z						biological_process											owl:Class	
GO:1901937	biolink:NamedThing	beta-caryophyllene biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-caryophyllene.	got7fsn_ti	beta-caryophyllene synthesis|beta-caryophyllene anabolism|beta-caryophyllene biosynthesis|beta-caryophyllene formation						ms	2013-02-18T14:55:18Z						biological_process											owl:Class	
GO:0045350	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904230	biolink:NamedThing	negative regulation of succinate dehydrogenase activity	Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity.	got7fsn_ti	inhibition of succinate:acceptor oxidoreductase activity|down regulation of succinate dehydrogenase activity|negative regulation of succinyl dehydrogenase activity|down-regulation of succinyl dehydrogenase activity|down regulation of succinate:acceptor oxidoreductase activity|inhibition of fumarate reductase activity|down-regulation of succinodehydrogenase activity|inhibition of fumaric hydrogenase activity|down regulation of succinic acid dehydrogenase activity|down-regulation of succinate:(acceptor) oxidoreductase activity|downregulation of succinate:(acceptor) oxidoreductase activity|downregulation of succinic acid dehydrogenase activity|inhibition of succinate dehydrogenase activity|down-regulation of fumarate dehydrogenase activity|down-regulation of succinate:acceptor oxidoreductase activity|inhibition of succinic acid dehydrogenase activity|down regulation of succinyl dehydrogenase activity|negative regulation of fumarate reductase activity|negative regulation of succinodehydrogenase activity|downregulation of succinate oxidoreductase activity|down regulation of succinodehydrogenase activity|down regulation of fumarate dehydrogenase activity|inhibition of succinate:(acceptor) oxidoreductase activity|down regulation of succinate:(acceptor) oxidoreductase activity|negative regulation of succinate oxidoreductase activity|down-regulation of succinate dehydrogenase activity|down regulation of fumarate reductase activity|down-regulation of fumaric hydrogenase activity|negative regulation of succinic acid dehydrogenase activity|down-regulation of fumarate reductase activity|downregulation of succinate:acceptor oxidoreductase activity|negative regulation of succinate:(acceptor) oxidoreductase activity|inhibition of fumarate dehydrogenase activity|downregulation of succinodehydrogenase activity|downregulation of fumaric hydrogenase activity|down-regulation of succinic acid dehydrogenase activity|inhibition of succinate oxidoreductase activity|down-regulation of succinate oxidoreductase activity|downregulation of fumarate reductase activity|negative regulation of succinate:acceptor oxidoreductase activity|inhibition of succinyl dehydrogenase activity|downregulation of succinate dehydrogenase activity|downregulation of fumarate dehydrogenase activity|down regulation of succinate oxidoreductase activity|negative regulation of fumarate dehydrogenase activity|inhibition of succinodehydrogenase activity|negative regulation of fumaric hydrogenase activity|downregulation of succinyl dehydrogenase activity|down regulation of fumaric hydrogenase activity						rl	2015-05-15T09:51:14Z						biological_process											owl:Class	
GO:0032829	biolink:NamedThing	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.	got7fsn_ti	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0061916	biolink:NamedThing	leading edge of axonal growth cone	That part of the axonal growth cone which represents the distal part of the structure.	got7fsn_ti	distal tip of axonal growth cone|axonal growth cone leading edge						dph	2017-07-10T19:17:21Z						cellular_component											owl:Class	
GO:1901880	biolink:NamedThing	negative regulation of protein depolymerization	Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.	got7fsn_ti	inhibition of protein polymer degradation|inhibition of protein polymer catabolism|inhibition of protein depolymerization|down-regulation of protein depolymerization|down regulation of protein polymer degradation|downregulation of protein depolymerization|down regulation of protein polymer catabolic process|negative regulation of protein polymer catabolic process|down regulation of protein polymer breakdown|down regulation of protein depolymerization|downregulation of protein polymer catabolic process|down regulation of protein polymer catabolism|downregulation of protein polymer breakdown|downregulation of protein polymer degradation|down-regulation of protein polymer breakdown|down-regulation of protein polymer catabolism|negative regulation of protein polymer degradation|down-regulation of protein polymer catabolic process|inhibition of protein polymer catabolic process|inhibition of protein polymer breakdown|down-regulation of protein polymer degradation|negative regulation of protein polymer breakdown|downregulation of protein polymer catabolism|negative regulation of protein polymer catabolism						rl	2013-02-06T13:57:28Z						biological_process											owl:Class	
CHEBI:26546	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075072	biolink:NamedThing	obsolete autophagy of symbiont cells involved in interaction with host	OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm during interaction with its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	autophagy of symbiont cells during interaction with host				The reason for obsoletion is that this term did not represent any specific host/symbiont process.					True				biological_process											owl:Class	
GO:0033323	biolink:NamedThing	choline biosynthetic process via CDP-choline	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.	got7fsn_ti	choline formation via CDP-choline|choline biosynthesis via CDP-choline|choline anabolism via CDP-choline|choline synthesis via CDP-choline											MetaCyc:PWY-3561|MetaCyc:PWY-4762		biological_process											owl:Class	
GO:1904852	biolink:NamedThing	trimethylamine-N-oxide reductase (cytochrome c) complex	A protein complex which is capable of trimethylamine-N-oxide reductase (cytochrome c) activity.	got7fsn_ti					An example of this is TorA in E. coli (UniProt ID P33225) in PMID:11056172 (inferred from direct assay).		bhm	2015-12-14T09:11:10Z						cellular_component											owl:Class	
GO:1905202	biolink:NamedThing	methylcrotonoyl-CoA carboxylase complex	A protein complex which is capable of methylcrotonoyl-CoA carboxylase activity.	got7fsn_ti							bf	2016-05-16T11:03:20Z						cellular_component											owl:Class	
GO:1905128	biolink:NamedThing	positive regulation of axo-dendritic protein transport	Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport.	got7fsn_ti	upregulation of axo-dendritic protein transport|positive regulation of axonal protein transport|up regulation of axonal protein transport|up-regulation of axonal protein transport|up-regulation of axo-dendritic protein transport|activation of axo-dendritic protein transport|up regulation of axo-dendritic protein transport|upregulation of axonal protein transport|activation of axonal protein transport						sl	2016-04-11T20:38:48Z						biological_process											owl:Class	
GO:1903609	biolink:NamedThing	negative regulation of inward rectifier potassium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity.	got7fsn_ti	down regulation of inward rectifier potassium channel activity|downregulation of Kir channel activity|inhibition of inward rectifier potassium channel activity|down-regulation of inward rectifier potassium channel activity|inhibition of Kir channel activity|down regulation of Kir channel activity|downregulation of inward rectifier potassium channel activity|down-regulation of Kir channel activity|negative regulation of Kir channel activity						rl	2014-11-14T20:29:14Z						biological_process											owl:Class	
GO:1902063	biolink:NamedThing	betaine aldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of betaine aldehyde.	got7fsn_ti	betaine aldehyde synthesis|betaine aldehyde anabolism|betaine aldehyde biosynthesis|betaine aldehyde formation						di	2013-04-16T12:07:17Z						biological_process											owl:Class	
GO:1904300	biolink:NamedThing	positive regulation of transcytosis	Any process that activates or increases the frequency, rate or extent of transcytosis.	got7fsn_ti	activation of transcytosis|up-regulation of transcytosis|upregulation of transcytosis|up regulation of transcytosis						sl	2015-06-09T22:53:38Z						biological_process											owl:Class	
GO:1901105	biolink:NamedThing	tetracenomycin C catabolic process	The chemical reactions and pathways resulting in the breakdown of tetracenomycin C.	got7fsn_ti	tetracenomycin C catabolism|tetracenomycin C breakdown|tetracenomycin C degradation						yaf	2012-07-11T02:50:54Z						biological_process											owl:Class	
GO:0080037	biolink:NamedThing	negative regulation of cytokinin-activated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.	got7fsn_ti	negative regulation of cytokinin mediated signaling pathway|negative regulation of cytokinin mediated signalling													biological_process											owl:Class	
GO:0044413	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903896	biolink:NamedThing	positive regulation of IRE1-mediated unfolded protein response	Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response.	got7fsn_ti	positive regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|upregulation of IRE1p unfolded protein response|up-regulation of IRE1 branch of UPR|up-regulation of UPR signaling by IRE1 stress sensor|positive regulation of IRE1 signaling in response to endoplasmic reticulum stress|positive regulation of UPR signaling by IRE1 stress sensor|upregulation of IRE1 branch of UPR|up regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|activation of IRE1 signaling in response to endoplasmic reticulum stress|activation of IRE1alpha unfolded protein response|up regulation of IRE1-mediated unfolded protein response|up-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|up-regulation of IRE1p unfolded protein response|up regulation of IRE1 signaling in response to endoplasmic reticulum stress|activation of IRE1-mediated unfolded protein response|upregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up regulation of IRE1alpha unfolded protein response|activation of IRE1p unfolded protein response|up regulation of UPR signaling by IRE1 stress sensor|positive regulation of ERN1-mediated unfolded protein response|up-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|positive regulation of IRE1alpha unfolded protein response|up-regulation of IRE1-mediated unfolded protein response|up regulation of IRE1 branch of UPR|up regulation of IRE1p unfolded protein response|upregulation of IRE1alpha unfolded protein response|upregulation of UPR signaling by IRE1 stress sensor|activation of IRE1 branch of UPR|upregulation of IRE1-mediated unfolded protein response|positive regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|activation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up-regulation of IRE1alpha unfolded protein response|up-regulation of IRE1 signaling in response to endoplasmic reticulum stress|activation of UPR signaling by IRE1 stress sensor|positive regulation of IRE1p unfolded protein response|positive regulation of IRE1 branch of UPR|up regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|activation of endoplasmic reticulum unfolded protein response; IRE1 signaling|upregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|upregulation of IRE1 signaling in response to endoplasmic reticulum stress						bf	2015-02-09T10:18:04Z						biological_process											owl:Class	
GO:2000581	biolink:NamedThing	obsolete negative regulation of microtubule motor activity, plus-end-directed	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.	got7fsn_ti	negative regulation of plus-end-directed kinesin ATPase activity|negative regulation of ATP-dependent microtubule motor activity, plus-end-directed|negative regulation of plus-end-directed microtubule motor activity|negative regulation of kinesin ATP phosphohydrolase (plus-end-directed)|negative regulation of kinesin activity	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140661	bf	2011-04-05T08:39:49Z		True				biological_process											owl:Class	
GO:1901874	biolink:NamedThing	negative regulation of post-translational protein modification	Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification.	got7fsn_ti	negative regulation of post-translational amino acid modification|down regulation of posttranslational protein modification|downregulation of post-translational protein modification|down-regulation of post-translational amino acid modification|downregulation of post-translational modification|negative regulation of posttranslational amino acid modification|down-regulation of post-translational modification|negative regulation of PTM|down-regulation of posttranslational modification|negative regulation of posttranslational protein modification|inhibition of posttranslational protein modification|downregulation of posttranslational modification|down regulation of posttranslational amino acid modification|down regulation of posttranslational modification|down-regulation of posttranslational amino acid modification|down regulation of post-translational protein modification|inhibition of posttranslational modification|inhibition of post-translational protein modification|inhibition of posttranslational amino acid modification|negative regulation of posttranslational modification|inhibition of post-translational modification|downregulation of PTM|down regulation of post-translational modification|down regulation of post-translational amino acid modification|inhibition of post-translational amino acid modification|downregulation of posttranslational amino acid modification|inhibition of PTM|down-regulation of post-translational protein modification|downregulation of post-translational amino acid modification|downregulation of posttranslational protein modification|negative regulation of post-translational modification|down-regulation of PTM|down-regulation of posttranslational protein modification|down regulation of PTM						yaf	2013-02-05T10:02:57Z						biological_process											owl:Class	
GO:0045969	biolink:NamedThing	positive regulation of juvenile hormone biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.	got7fsn_ti	positive regulation of juvenile hormone anabolism|positive regulation of juvenile hormone formation|up regulation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone biosynthesis|upregulation of juvenile hormone biosynthetic process|stimulation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone synthesis|activation of juvenile hormone biosynthetic process|up-regulation of juvenile hormone biosynthetic process													biological_process											owl:Class	
GO:1905698	biolink:NamedThing	positive regulation of polysome binding	Any process that activates or increases the frequency, rate or extent of polysome binding.	got7fsn_ti	activation of polysome binding|upregulation of polyribosome binding|upregulation of polysome binding|up-regulation of polyribosome binding|positive regulation of polyribosome binding|up regulation of polysome binding|up-regulation of polysome binding|up regulation of polyribosome binding|activation of polyribosome binding						bc	2016-11-14T23:26:37Z						biological_process											owl:Class	
UBERON:0000467	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001019	biolink:NamedThing	positive regulation of retrograde axon cargo transport	Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.	got7fsn_ti	positive regulation of retrograde axonal transport						kmv	2011-08-11T09:44:49Z						biological_process											owl:Class	
GO:2000762	biolink:NamedThing	regulation of phenylpropanoid metabolic process	Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process.	got7fsn_ti	regulation of phenylpropanoid metabolism						tb	2011-06-17T06:13:43Z						biological_process											owl:Class	
GO:1900014	biolink:NamedThing	obsolete cellular response to calcium ion involved in chemotaxis to cAMP	OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.	got7fsn_ti	cellular response to calcium ion of chemotaxis to cAMP|cellular response to calcium ion involved in chemotaxis to cAMP|cellular response to Ca2+ ion of chemotaxis to 3',5'-cAMP|cellular response to calcium ion of chemotaxis to cyclic AMP|cellular response to Ca2+ ion of chemotaxis to cyclic AMP|cellular response to calcium ion of chemotaxis to 3',5'-cAMP|cellular response to Ca2+ ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to Ca2+ ion of chemotaxis to 3',5' cAMP|cellular response to calcium ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to calcium ion of chemotaxis to 3',5' cAMP|cellular response to Ca2+ ion of chemotaxis to cAMP						pr	2012-01-11T08:06:58Z		True				biological_process											owl:Class	
GO:0043032	biolink:NamedThing	positive regulation of macrophage activation	Any process that stimulates, induces or increases the rate of macrophage activation.	got7fsn_ti	upregulation of macrophage activation|activation of macrophage activation|positive regulation of macrophage polarization|stimulation of macrophage activation|up regulation of macrophage activation|up-regulation of macrophage activation													biological_process											owl:Class	
GO:0004239	biolink:NamedThing	obsolete methionyl aminopeptidase activity	OBSOLETE. Catalysis of the release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.	got7fsn_ti	methionyl aminopeptidase activity|peptidase M activity|methionine aminopeptidase activity|L-methionine aminopeptidase activity|MAP				This term was made obsolete because it represents a gene product.	GO:0004177|GO:0008235|GO:0070084				True		EC:3.4.11.18|MetaCyc:3.4.11.18-RXN		molecular_function											owl:Class	
GO:0046147	biolink:NamedThing	tetrahydrobiopterin catabolic process	The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.	got7fsn_ti	tetrahydrobiopterin breakdown|5,6,7,8-tetrahydrobiopterin catabolic process|tetrahydrobiopterin catabolism|tetrahydrobiopterin degradation													biological_process											owl:Class	
GO:0052711	biolink:NamedThing	obsolete ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine	OBSOLETE. The pathway resulting in the formation of ergothioneine from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).	got7fsn_ti	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism to ergothioneine|histidine betaine catabolism to ergothioneine|hercynine catabolism to ergothioneine|ergothioneine biosynthesis from hercynine|ergothioneine biosynthesis from histidine betaine	https://github.com/geneontology/go-ontology/issues/11163			The reason for obsoletion is that this term does not provide a useful distinction from its parent, GO:0052704 (because that trimethyl-His yada is present in both pathways)			2011-08-05T04:06:16Z		True		KEGG_REACTION:R04878		biological_process											owl:Class	
GO:1900261	biolink:NamedThing	positive regulation of RNA-directed 5'-3' RNA polymerase activity	Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.	got7fsn_ti	upregulation of transcriptase|up-regulation of RDRP|activation of RNA synthetase activity|up regulation of RNA synthetase activity|upregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|up regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|up-regulation of ribonucleic replicase activity|up regulation of polymerase L|upregulation of PB1 proteins|positive regulation of RNA-directed RNA polymerase activity|upregulation of 3D polymerase activity|positive regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|activation of RNA replicase activity|activation of RNA-dependent RNA replicase activity|up regulation of ribonucleic synthetase activity|positive regulation of ribonucleic acid replicase activity|positive regulation of RNA replicase activity|up regulation of RDRP|upregulation of RNA nucleotidyltransferase (RNA-directed) activity|activation of RDRP|up regulation of PB1 proteins|positive regulation of Q-beta replicase activity|upregulation of RNA replicase activity|up-regulation of RNA-dependent RNA polymerase activity|up-regulation of PB1 proteins|positive regulation of PB1 proteins|up-regulation of ribonucleic synthetase activity|activation of RNA-directed RNA polymerase activity|upregulation of RNA synthetase activity|positive regulation of PB2 proteins|up-regulation of PB2 proteins|activation of 3D polymerase activity|up regulation of transcriptase|positive regulation of polymerase L|up-regulation of Q-beta replicase activity|up-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|positive regulation of RDRP|up regulation of RNA replicase activity|up-regulation of RNA nucleotidyltransferase (RNA-directed) activity|upregulation of RNA-dependent ribonucleate nucleotidyltransferase activity|up regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|upregulation of ribonucleic synthetase activity|activation of Q-beta replicase activity|up-regulation of 3D polymerase activity|activation of ribonucleic synthetase activity|activation of RNA nucleotidyltransferase (RNA-directed) activity|up-regulation of polymerase L|upregulation of RDRP|up-regulation of transcriptase|upregulation of Q-beta replicase activity|upregulation of ribonucleic acid replicase activity|up regulation of Q-beta replicase activity|positive regulation of RNA-dependent RNA polymerase activity|activation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|upregulation of RNA-dependent RNA replicase activity|positive regulation of phage f2 replicase|activation of ribonucleic acid-dependent ribonucleic acid polymerase activity|positive regulation of RNA-dependent RNA replicase activity|positive regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|up regulation of phage f2 replicase|up regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|up regulation of PB2 proteins|activation of polymerase L|up regulation of ribonucleic replicase activity|up regulation of ribonucleic acid replicase activity|up regulation of 3D polymerase activity|positive regulation of ribonucleic synthetase activity|positive regulation of RNA nucleotidyltransferase (RNA-directed) activity|up-regulation of phage f2 replicase|up-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|positive regulation of RNA synthetase activity|activation of RNA-dependent RNA polymerase activity|up-regulation of RNA synthetase activity|upregulation of RNA-dependent RNA polymerase activity|up-regulation of RNA-directed RNA polymerase activity|activation of PB1 proteins|up-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up regulation of RNA-directed RNA polymerase activity|activation of ribonucleic replicase activity|activation of PB2 proteins|up regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|activation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|activation of ribonucleic acid replicase activity|activation of transcriptase|positive regulation of 3D polymerase activity|activation of RNA-dependent ribonucleate nucleotidyltransferase activity|upregulation of ribonucleic replicase activity|positive regulation of transcriptase|positive regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|upregulation of phage f2 replicase|positive regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up-regulation of RNA-dependent RNA replicase activity|upregulation of PB2 proteins|upregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|positive regulation of ribonucleic replicase activity|up-regulation of ribonucleic acid replicase activity|upregulation of polymerase L|up regulation of RNA nucleotidyltransferase (RNA-directed) activity|upregulation of RNA-directed RNA polymerase activity|up regulation of RNA-dependent RNA replicase activity|up-regulation of RNA replicase activity|up-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|upregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|activation of phage f2 replicase|up regulation of RNA-dependent RNA polymerase activity						tb	2012-04-03T11:02:11Z						biological_process											owl:Class	
GO:1903994	biolink:NamedThing	obsolete positive regulation of protein stabilization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of protein stabilization.	got7fsn_ti	upregulation of protein stabilization activity|positive regulation of positive regulation of protein stability|up regulation of protein stabilization activity|positive regulation of protein stabilization activity|positive regulation of lysosomal protein stabilization|up regulation of protein sequestering|activation of positive regulation of protein stability|up regulation of positive regulation of protein stability|upregulation of protein stabilization|up regulation of lysosomal protein stabilization|up regulation of protein stabilization|activation of lysosomal protein stabilization|upregulation of lysosomal protein stabilization|up-regulation of protein stabilization activity|upregulation of protein sequestering|up-regulation of lysosomal protein stabilization|positive regulation of protein sequestering|up-regulation of protein stabilization|activation of protein sequestering|activation of protein stabilization activity|upregulation of positive regulation of protein stability|up-regulation of protein sequestering|positive regulation of protein stabilization|up-regulation of positive regulation of protein stability|activation of protein stabilization				This term was made obsolete because it was created in error.	GO:0050821	pga	2015-03-05T13:33:00Z		True				biological_process											owl:Class	
GO:1990129	biolink:NamedThing	obsolete pre-primosome complex involved in replication restart	OBSOLETE. A protein-DNA complex involved in replication restart after a stalled replication fork has been repaired.	got7fsn_ti	pre-primosome complex involved in replication restart				This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2013-06-24T10:36:30Z		True				cellular_component											owl:Class	
GO:1904535	biolink:NamedThing	positive regulation of telomeric loop disassembly	Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.	got7fsn_ti	up regulation of telomeric loop disassembly|activation of telomeric loop disassembly|activation of T loop disassembly|up regulation of T loop disassembly|upregulation of T loop disassembly|upregulation of telomeric loop disassembly|up-regulation of T loop disassembly|up-regulation of telomeric loop disassembly|positive regulation of T loop disassembly						nc	2015-07-31T17:15:10Z						biological_process											owl:Class	
GO:1990549	biolink:NamedThing	mitochondrial NAD transmembrane transport	The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:09:51Z						biological_process											owl:Class	
GO:1900916	biolink:NamedThing	positive regulation of octadecene biosynthetic process	Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process.	got7fsn_ti	up-regulation of octadecene biosynthesis|upregulation of octadecene synthesis|upregulation of 1-octadecene biosynthetic process|positive regulation of octadecene synthesis|up-regulation of octadecene synthesis|up regulation of octadecene formation|up regulation of octadecene biosynthetic process|activation of octadecene formation|up regulation of octadecene biosynthesis|upregulation of octadecene anabolism|up regulation of octadecene synthesis|up-regulation of 1-octadecene biosynthetic process|up-regulation of octadecene anabolism|activation of octadecene anabolism|positive regulation of octadecene biosynthesis|upregulation of octadecene formation|up regulation of 1-octadecene biosynthetic process|activation of octadecene synthesis|activation of octadecene biosynthesis|up regulation of octadecene anabolism|positive regulation of octadecene anabolism|activation of 1-octadecene biosynthetic process|activation of octadecene biosynthetic process|upregulation of octadecene biosynthesis|up-regulation of octadecene formation|positive regulation of octadecene formation|up-regulation of octadecene biosynthetic process|upregulation of octadecene biosynthetic process|positive regulation of 1-octadecene biosynthetic process						tt	2012-06-13T04:24:55Z						biological_process											owl:Class	
GO:0000363	biolink:NamedThing	obsolete first U12-type spliceosomal transesterification activity	OBSOLETE. Catalysis of the first transesterification reaction of U12-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6atac snRNA and/or U2atac snRNA, and/or associated proteins.	got7fsn_ti	first U12-type spliceosomal transesterification activity|lariat formation, 5'-splice site cleavage			GO:0000384	This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.					True				molecular_function											owl:Class	
GO:0030105	biolink:NamedThing	obsolete anaphylaxis	OBSOLETE. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances.	got7fsn_ti	anaphylaxis				This term was made obsolete because it represents a an abnormal process that is harmful to the organism.	GO:0006955				True				biological_process											owl:Class	
CHEBI:21188	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048783	biolink:NamedThing	positive regulation of cyanophore differentiation	Any process that activates or increases the frequency, rate or extent of cyanophore differentiation.	got7fsn_ti	up-regulation of cyanophore differentiation|upregulation of cyanophore differentiation|stimulation of cyanophore differentiation|up regulation of cyanophore differentiation|activation of cyanophore differentiation													biological_process											owl:Class	
GO:1905163	biolink:NamedThing	negative regulation of phagosome maturation	Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation.	got7fsn_ti	downregulation of phagosome maturation|down regulation of phagosome maturation|inhibition of phagosome maturation|down-regulation of phagosome maturation						bf	2016-04-25T16:28:11Z						biological_process											owl:Class	
GO:0017026	biolink:NamedThing	obsolete procollagen C-endopeptidase activity	OBSOLETE. Catalysis of the cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III.	got7fsn_ti	procollagen C-terminal proteinase activity|procollagen C-endopeptidase activity|procollagen carboxypeptidase activity|carboxyprocollagen peptidase activity|procollagen C-proteinase activity|procollagen peptidase activity|procollagen carboxy-terminal proteinase activity|procollagen C-terminal peptidase activity|BMP1			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1900413	biolink:NamedThing	obsolete positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of phospholipid biosynthetic process.	got7fsn_ti	positive regulation of phospholipid synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phospholipid biosynthesis by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T03:41:58Z		True				biological_process											owl:Class	
CHEBI:33575	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901716	biolink:NamedThing	negative regulation of gamma-aminobutyric acid catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process.	got7fsn_ti	downregulation of gamma-aminobutyric acid catabolic process|inhibition of GABA catabolism|downregulation of gamma-aminobutyric acid degradation|down regulation of gamma-aminobutyric acid breakdown|negative regulation of gamma-aminobutyric acid breakdown|down regulation of gamma-aminobutyric acid catabolic process|inhibition of gamma-aminobutyric acid catabolic process|down regulation of gamma-aminobutyric acid degradation|negative regulation of GABA catabolic process|negative regulation of gamma-aminobutyric acid degradation|negative regulation of 4-aminobutanoate catabolism|downregulation of 4-aminobutyrate catabolic process|inhibition of 4-aminobutanoate catabolic process|down-regulation of GABA catabolism|inhibition of gamma-aminobutyric acid catabolism|downregulation of 4-aminobutanoate catabolic process|negative regulation of GABA catabolism|down regulation of 4-aminobutyrate catabolic process|down regulation of GABA catabolic process|downregulation of gamma-aminobutyric acid breakdown|down-regulation of gamma-aminobutyric acid catabolism|down-regulation of gamma-aminobutyric acid breakdown|inhibition of 4-aminobutyrate catabolism|down regulation of 4-aminobutanoate catabolism|down-regulation of 4-aminobutyrate catabolism|negative regulation of 4-aminobutyrate catabolic process|down-regulation of gamma-aminobutyric acid degradation|inhibition of 4-aminobutyrate catabolic process|down-regulation of 4-aminobutanoate catabolism|downregulation of GABA catabolic process|inhibition of gamma-aminobutyric acid degradation|downregulation of 4-aminobutanoate catabolism|down-regulation of 4-aminobutyrate catabolic process|down regulation of GABA catabolism|inhibition of gamma-aminobutyric acid breakdown|inhibition of GABA catabolic process|negative regulation of gamma-aminobutyric acid catabolism|negative regulation of 4-aminobutanoate catabolic process|down-regulation of 4-aminobutanoate catabolic process|inhibition of 4-aminobutanoate catabolism|downregulation of 4-aminobutyrate catabolism|downregulation of gamma-aminobutyric acid catabolism|down regulation of 4-aminobutanoate catabolic process|down-regulation of gamma-aminobutyric acid catabolic process|negative regulation of 4-aminobutyrate catabolism|down regulation of 4-aminobutyrate catabolism|down regulation of gamma-aminobutyric acid catabolism|down-regulation of GABA catabolic process|downregulation of GABA catabolism						mcc	2012-12-19T16:13:31Z						biological_process											owl:Class	
GO:0002611	biolink:NamedThing	negative regulation of plasmacytoid dendritic cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.	got7fsn_ti	down-regulation of plasmacytoid dendritic cell antigen processing and presentation|down regulation of plasmacytoid dendritic cell antigen processing and presentation|downregulation of plasmacytoid dendritic cell antigen processing and presentation|inhibition of plasmacytoid dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:1900775	biolink:NamedThing	fumiquinazoline biosynthetic process	The chemical reactions and pathways resulting in the formation of fumiquinazoline.	got7fsn_ti	fumiquinazoline formation|fumiquinazolines synthesis|fumiquinazolines anabolism|fumiquinazoline biosynthesis|fumiquinazoline synthesis|fumiquinazolines formation|fumiquinazoline anabolism|fumiquinazolines biosynthetic process|fumiquinazolines biosynthesis						di	2012-06-04T09:29:54Z						biological_process											owl:Class	
GO:0019449	biolink:NamedThing	L-cysteine catabolic process to hypotaurine	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine.	got7fsn_ti	L-cysteine breakdown to hypotaurine|L-cysteine degradation to hypotaurine													biological_process											owl:Class	
GO:1902024	biolink:NamedThing	L-histidine transport	The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							kmv	2013-03-27T16:09:15Z						biological_process											owl:Class	
GO:1903549	biolink:NamedThing	positive regulation of growth hormone activity	Any process that activates or increases the frequency, rate or extent of growth hormone activity.	got7fsn_ti	activation of placental growth hormone activity|up regulation of pituitary growth hormone activity|upregulation of placental growth hormone activity|up regulation of growth hormone activity|up regulation of GH activity|activation of growth hormone activity|positive regulation of GH activity|positive regulation of pituitary growth hormone activity|up-regulation of GH activity|positive regulation of placental growth hormone activity|up-regulation of pituitary growth hormone activity|upregulation of growth hormone activity|activation of pituitary growth hormone activity|upregulation of GH activity|up regulation of placental growth hormone activity|up-regulation of growth hormone activity|activation of GH activity|upregulation of pituitary growth hormone activity|up-regulation of placental growth hormone activity						mr	2014-10-20T15:18:53Z						biological_process											owl:Class	
GO:2001273	biolink:NamedThing	obsolete regulation of glucose import in response to insulin stimulus	OBSOLETE. Any process that modulates the frequency, rate or extent of glucose import in response to insulin stimulus.	got7fsn_ti	regulation of cellular glucose import in response to insulin stimulus	https://github.com/geneontology/go-ontology/issues/15961			This term was obsoleted because it represents a GO-CAM model.		vk	2011-12-13T12:29:31Z		True				biological_process											owl:Class	
GO:0001924	biolink:NamedThing	regulation of B-1 B cell differentiation	Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.	got7fsn_ti	regulation of B-1 B-cell differentiation|regulation of B-1 B lymphocyte differentiation|regulation of B-1 B-lymphocyte differentiation|regulation of B-1 B cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0016113	biolink:NamedThing	polyterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.	got7fsn_ti	polyterpenoid catabolism|polyterpene catabolic process|polyterpene catabolism|polyterpenoid degradation|polyterpenoid breakdown													biological_process											owl:Class	
GO:0120123	biolink:NamedThing	ubiquitin activating enzyme complex	A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.	got7fsn_ti	E1 ubiquitin-activating enzyme|E1 complex						krc	2018-01-29T19:28:56Z						cellular_component											owl:Class	
GO:1904257	biolink:NamedThing	zinc ion import into Golgi apparatus	The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi apparatus.	got7fsn_ti	zinc II ion import across Golgi membrane|zinc(2+) import across Golgi membrane|zinc ion import across Golgi membrane|zinc ion import into Golgi membrane						tb	2015-05-20T19:56:18Z						biological_process											owl:Class	
GO:0039535	biolink:NamedThing	regulation of RIG-I signaling pathway	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.	got7fsn_ti	regulation of RIG-I signalling pathway|regulation of retinoic acid inducible gene I signaling pathway|regulation of DDX58 signaling pathway						bf	2012-01-03T11:24:29Z						biological_process											owl:Class	
GO:0070245	biolink:NamedThing	positive regulation of thymocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.	got7fsn_ti	activation of thymocyte apoptosis|positive regulation of thymocyte apoptosis|up regulation of thymocyte apoptosis|positive regulation of immature T cell apoptosis|stimulation of thymocyte apoptosis|upregulation of thymocyte apoptosis|up-regulation of thymocyte apoptosis				Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).									biological_process											owl:Class	
GO:1900149	biolink:NamedThing	positive regulation of Schwann cell migration	Any process that activates or increases the frequency, rate or extent of Schwann cell migration.	got7fsn_ti	up-regulation of Schwann cell migration|up regulation of Schwann cell migration|upregulation of Schwann cell migration|activation of Schwann cell migration						bf	2012-03-06T04:14:58Z						biological_process											owl:Class	
GO:0035863	biolink:NamedThing	dITP catabolic process	The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.	got7fsn_ti	dITP breakdown|2'-Deoxyinosine-5'-triphosphate catabolic process|dITP degradation|2'-Deoxyinosine 5'-triphosphate catabolic process|dITP catabolism|deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) catabolic process|deoxyinosine 5'-triphosphate catabolic process						bf	2011-05-25T02:55:21Z						biological_process											owl:Class	
GO:1902994	biolink:NamedThing	regulation of phospholipid efflux	Any process that modulates the frequency, rate or extent of phospholipid efflux.	got7fsn_ti	regulation of phospholipid export						sjp	2014-05-08T14:55:16Z						biological_process											owl:Class	
GO:0042344	biolink:NamedThing	indole glucosinolate catabolic process	The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.	got7fsn_ti	indole glucosinolate degradation|indole glucosinolate catabolism|indole glucosinolate breakdown													biological_process											owl:Class	
GO:0032092	biolink:NamedThing	positive regulation of protein binding	Any process that activates or increases the frequency, rate or extent of protein binding.	got7fsn_ti	stimulation of protein binding|up regulation of protein binding|activation of protein binding|upregulation of protein binding|up-regulation of protein binding													biological_process											owl:Class	
GO:0018333	biolink:NamedThing	obsolete enzyme active site formation via O-phospho-L-threonine	OBSOLETE. The transient phosphorylation of peptidyl-threonine to form O-phospho-L-threonine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it was created by error: tyrosine phosphorylation does not generate an active site.					True		RESID:AA0038		biological_process											owl:Class	
GO:0030576	biolink:NamedThing	Cajal body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.	got7fsn_ti	Cajal body organization and biogenesis|Cajal body organisation				See also the cellular component term 'Cajal body ; GO:0015030'.									biological_process											owl:Class	
GO:1902415	biolink:NamedThing	regulation of mRNA binding	Any process that modulates the frequency, rate or extent of mRNA binding.	got7fsn_ti							rb	2013-09-13T18:57:15Z						biological_process											owl:Class	
GO:0005043	biolink:NamedThing	netrin receptor activity involved in chemorepulsion	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.	got7fsn_ti	repulsive netrin receptor activity|netrin receptor activity involved in negative chemotaxis													molecular_function											owl:Class	
GO:0071792	biolink:NamedThing	bacillithiol metabolic process	The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.	got7fsn_ti	bacillithiol metabolism						mah	2010-09-02T11:13:47Z						biological_process											owl:Class	
GO:0070602	biolink:NamedThing	regulation of centromeric sister chromatid cohesion	Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.	got7fsn_ti	regulation of sister chromatid cohesion at centromere						mah	2009-04-28T04:32:53Z						biological_process											owl:Class	
GO:1902900	biolink:NamedThing	gut granule assembly	The aggregation, arrangement and bonding together of a set of components to form a gut granule.	got7fsn_ti	gut granule biogenesis|gut granule formation						kmv	2014-04-14T14:28:17Z						biological_process											owl:Class	
GO:0033686	biolink:NamedThing	positive regulation of luteinizing hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.	got7fsn_ti	stimulation of luteinizing hormone secretion|up-regulation of luteinizing hormone secretion|up regulation of luteinizing hormone secretion|activation of luteinizing hormone secretion|upregulation of luteinizing hormone secretion													biological_process											owl:Class	
GO:0032213	biolink:NamedThing	regulation of telomere maintenance via semi-conservative replication	Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA.	got7fsn_ti														biological_process											owl:Class	
GO:1902717	biolink:NamedThing	obsolete sequestering of iron ion	OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of iron ion.	got7fsn_ti	sequestering of iron ion				This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2014-02-24T16:08:43Z		True				biological_process											owl:Class	
GO:1904239	biolink:NamedThing	regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.	got7fsn_ti	regulation of p97-Ufd1-Npl4 complex formation|regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|regulation of p97-Ufd1-Npl4 complex assembly|regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly						bf	2015-05-18T09:50:21Z						biological_process											owl:Class	
GO:1902669	biolink:NamedThing	positive regulation of axon guidance	Any process that activates or increases the frequency, rate or extent of axon guidance.	got7fsn_ti	up-regulation of axon pathfinding|upregulation of axon pathfinding|upregulation of axon chemotaxis|activation of axon chemotaxis|up regulation of axon chemotaxis|activation of axon growth cone guidance|up regulation of axon pathfinding|up regulation of axon growth cone guidance|upregulation of axon guidance|positive regulation of axon growth cone guidance|positive regulation of axon pathfinding|up-regulation of axon chemotaxis|positive regulation of axon chemotaxis|up-regulation of axon growth cone guidance|up regulation of axon guidance|activation of axon guidance|upregulation of axon growth cone guidance|up-regulation of axon guidance|activation of axon pathfinding						hjd	2014-01-31T18:50:29Z						biological_process											owl:Class	
GO:1904087	biolink:NamedThing	negative regulation of epiboly involved in gastrulation with mouth forming second	Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.	got7fsn_ti	down regulation of epiboly involved in gastrulation with mouth forming second|downregulation of epiboly involved in gastrulation with mouth forming second|down-regulation of epiboly involved in gastrulation with mouth forming second|inhibition of epiboly involved in gastrulation with mouth forming second						dos	2015-03-25T11:17:41Z						biological_process											owl:Class	
GO:1904920	biolink:NamedThing	obsolete regulation of MAPK cascade involved in axon regeneration	OBSOLETE. Any process that modulates the frequency, rate or extent of MAPK cascade involved in axon regeneration.	got7fsn_ti	regulation of ERK/MAPK cascade involved in axon regeneration|regulation of mitogen-activated protein kinase cascade involved in axon regeneration|regulation of MAPKKK cascade during sporulation involved in axon regeneration|regulation of MAP kinase cascade involved in axon regeneration|regulation of MAPK signal transduction involved in axon regeneration|regulation of MAPK signaling involved in axon regeneration|regulation of MAP kinase kinase kinase cascade involved in axon regeneration|regulation of MAPK signalling involved in axon regeneration|regulation of MAPKKK cascade involved in axon regeneration	https://github.com/geneontology/go-ontology/issues/14323			This term was obsoleted because it represents a GO-CAM model.		kmv	2016-01-25T17:03:35Z		True				biological_process											owl:Class	
GO:1904915	biolink:NamedThing	positive regulation of establishment of protein-containing complex localization to telomere	Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.	got7fsn_ti	up-regulation of establishment of macromolecular complex localisation to telomere|activation of establishment of macromolecular complex localisation to telomere|activation of establishment of macromolecular complex localization to telomere|positive regulation of establishment of macromolecular complex localisation to telomere|upregulation of establishment of macromolecular complex localisation to telomere|up regulation of establishment of macromolecular complex localization to telomere|up regulation of establishment of macromolecular complex localisation to telomere|upregulation of establishment of macromolecular complex localization to telomere|up-regulation of establishment of macromolecular complex localization to telomere|positive regulation of establishment of macromolecular complex localization to telomere						rph	2016-01-19T10:38:36Z						biological_process											owl:Class	
GO:1904697	biolink:NamedThing	regulation of acinar cell proliferation	Any process that modulates the frequency, rate or extent of acinar cell proliferation.	got7fsn_ti	regulation of acinic cell proliferation|regulation of acinous cell proliferation						sl	2015-09-30T15:19:50Z						biological_process											owl:Class	
GO:0009335	biolink:NamedThing	obsolete holo-[acyl-carrier protein] synthase complex	OBSOLETE. An enzyme complex that catalyzes the formation of holo-[acyl-carrier protein] from CoA and apo-[acyl-carrier protein].	got7fsn_ti	holo-ACP synthase complex|holo-[acyl-carrier protein] synthase complex				This term was made obsolete because the catalytic activity resides in a single polypeptide rather than a complex, and the complex is represented by a different GO term.	GO:0005835				True				cellular_component											owl:Class	
GO:1905118	biolink:NamedThing	positive regulation of ribonucleoside-diphosphate reductase activity	Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.	got7fsn_ti	up-regulation of class II ribonucleoside-diphosphate reductase activity|up regulation of RNR|upregulation of purine/pyrimidine nucleoside diphosphate reduction|upregulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|upregulation of adenosylcobalamin-dependent ribonucleotide reductase activity|up-regulation of ribonucleotide diphosphate reductase activity|upregulation of class II ribonucleotide reductase activity|up regulation of ribonucleoside-diphosphate reductase activity|up-regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|up-regulation of nucleoside diphosphate reductase activity|activation of class I ribonucleotide reductase activity|upregulation of ribonucleoside-diphosphate reductase activity|up regulation of class I ribonucleotide reductase activity|up-regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|up regulation of class II ribonucleotide reductase activity|positive regulation of purine/pyrimidine nucleoside diphosphate reduction|activation of adenosylcobalamin-dependent ribonucleotide reductase activity|upregulation of ribonucleoside 5'-diphosphate reductase activity|up regulation of class II ribonucleoside-diphosphate reductase activity|up regulation of class III ribonucleotide reductase activity|up-regulation of ribonucleoside-diphosphate reductase activity|activation of ribonucleotide diphosphate reductase activity|up regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|upregulation of ribonucleotide diphosphate reductase activity|up regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|upregulation of class I ribonucleotide reductase activity|activation of ribonucleoside-diphosphate reductase activity|positive regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|up-regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|positive regulation of ribonucleotide diphosphate reductase activity|up-regulation of purine/pyrimidine nucleoside diphosphate reduction|positive regulation of nucleoside diphosphate reductase activity|positive regulation of RNR|activation of class II ribonucleotide reductase activity|positive regulation of class II ribonucleoside-diphosphate reductase activity|activation of class III ribonucleotide reductase activity|upregulation of class III ribonucleotide reductase activity|activation of nucleoside diphosphate reductase activity|upregulation of RNR|up regulation of purine/pyrimidine nucleoside diphosphate reduction|positive regulation of class I ribonucleotide reductase activity|activation of ribonucleoside 5'-diphosphate reductase activity|positive regulation of class III ribonucleotide reductase activity|up regulation of ribonucleotide diphosphate reductase activity|positive regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|up-regulation of RNR|activation of class II ribonucleoside-diphosphate reductase activity|up-regulation of class I ribonucleotide reductase activity|activation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|upregulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|up regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|positive regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|upregulation of nucleoside diphosphate reductase activity|up regulation of ribonucleoside 5'-diphosphate reductase activity|up regulation of nucleoside diphosphate reductase activity|activation of purine/pyrimidine nucleoside diphosphate reduction|up-regulation of class III ribonucleotide reductase activity|activation of RNR|up-regulation of ribonucleoside 5'-diphosphate reductase activity|positive regulation of class II ribonucleotide reductase activity|activation of aerobic non-heme iron-dependent ribonucleotide reductase activity|up-regulation of class II ribonucleotide reductase activity|positive regulation of ribonucleoside 5'-diphosphate reductase activity|upregulation of class II ribonucleoside-diphosphate reductase activity				An example of this is DRE2 in Saccharomyces cerevisiae (UniProt ID P36152) in PMID:24733891 (inferred from mutant phenotype).		bhm	2016-04-08T08:06:35Z						biological_process											owl:Class	
GO:1900275	biolink:NamedThing	negative regulation of phospholipase C activity	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity.	got7fsn_ti	downregulation of phospholipase C activity|down regulation of lipophosphodiesterase C|inhibition of lipophosphodiesterase C|down regulation of phosphatidase C|down-regulation of lecithinase C activity|inhibition of lecithinase C activity|downregulation of lecithinase C activity|down-regulation of phosphatidase C|negative regulation of lipophosphodiesterase C|down-regulation of phospholipase C activity|negative regulation of phosphatidase C|downregulation of phosphatidase C|down-regulation of lipophosphodiesterase C|down regulation of phospholipase C activity|downregulation of lipophosphodiesterase C|inhibition of phospholipase C activity|down regulation of lecithinase C activity|inhibition of phosphatidase C|negative regulation of lecithinase C activity						rl	2012-04-04T01:19:10Z						biological_process											owl:Class	
GO:1904267	biolink:NamedThing	negative regulation of Schwann cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis.	got7fsn_ti	down-regulation of Schwann cell chemotaxis|inhibition of Schwann cell chemotaxis|down regulation of Schwann cell chemotaxis|downregulation of Schwann cell chemotaxis						sl	2015-05-28T17:47:48Z						biological_process											owl:Class	
GO:1900458	biolink:NamedThing	negative regulation of brassinosteroid mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway.	got7fsn_ti	down regulation of brassinosteroid mediated signalling|negative regulation of brassinosteroid mediated signalling|down regulation of brassinosteroid mediated signaling pathway|downregulation of brassinosteroid mediated signalling|down-regulation of brassinosteroid mediated signaling pathway|inhibition of brassinosteroid mediated signaling pathway|down-regulation of brassinosteroid mediated signalling|inhibition of brassinosteroid mediated signalling|downregulation of brassinosteroid mediated signaling pathway						dhl	2012-05-01T06:12:13Z						biological_process											owl:Class	
GO:2000536	biolink:NamedThing	negative regulation of entry of bacterium into host cell	Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell.	got7fsn_ti	negative regulation of bacterial entry into host cell|negative regulation of invasion of bacteria into host cell						ebc	2011-03-28T09:52:23Z						biological_process											owl:Class	
GO:1905252	biolink:NamedThing	obsolete regulation of epidermal growth factor receptor signaling pathway involved in heart process	OBSOLETE. Any regulation of epidermal growth factor receptor signaling pathway that is involved in heart process.	got7fsn_ti	regulation of EGF receptor signalling pathway involved in cardiac process|regulation of EGF receptor signalling pathway involved in heart process|regulation of EGFR signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in heart process|regulation of EGFR signaling pathway involved in heart process|regulation of epidermal growth factor receptor signaling pathway involved in cardiac process				This term was obsoleted at the TermGenie Gatekeeper stage.		bc	2016-06-10T09:21:02Z		True				biological_process											owl:Class	
GO:1900976	biolink:NamedThing	positive regulation of tatiopterin biosynthetic process	Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process.	got7fsn_ti	activation of tatiopterin synthesis|up-regulation of tatiopterin biosynthesis|positive regulation of tatiopterin synthesis|up regulation of tatiopterin anabolism|activation of tatiopterin biosynthetic process|up-regulation of tatiopterin formation|activation of tatiopterin anabolism|up-regulation of tatiopterin anabolism|up-regulation of tatiopterin synthesis|activation of tatiopterin biosynthesis|up-regulation of tatiopterin biosynthetic process|upregulation of tatiopterin biosynthetic process|up regulation of tatiopterin formation|up regulation of tatiopterin synthesis|upregulation of tatiopterin synthesis|upregulation of tatiopterin formation|activation of tatiopterin formation|positive regulation of tatiopterin formation|up regulation of tatiopterin biosynthesis|upregulation of tatiopterin anabolism|positive regulation of tatiopterin biosynthesis|upregulation of tatiopterin biosynthesis|up regulation of tatiopterin biosynthetic process|positive regulation of tatiopterin anabolism						tt	2012-06-14T04:02:14Z						biological_process											owl:Class	
GO:1904488	biolink:NamedThing	regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter	A positive regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process.	got7fsn_ti	regulation of reactive oxygen species metabolism by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by up regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolism by upregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by stimulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up-regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by stimulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by activation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of global transcription from Pol II promoter|regulation of ROS metabolic process by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by positive regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by stimulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by activation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up-regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by upregulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by activation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by upregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by upregulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by activation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of global transcription from Pol II promoter|regulation of ROS metabolic process by stimulation of global transcription from RNA polymerase II promoter						kmv	2015-07-17T18:11:59Z						biological_process											owl:Class	
GO:1902032	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress	OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in response to osmotic stress.	got7fsn_ti	regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic response|global transcription regulation from Pol II promoter involved in osmotic response|regulation of global transcription from Pol II promoter involved in response to osmotic stress|regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress|regulation of transcription from Pol II promoter involved in response to osmotic stress|regulation of transcription from Pol II promoter involved in osmotic stress response|regulation of transcription from Pol II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter involved in osmotic stress response|regulation of transcription from RNA polymerase II promoter, global involved in osmotic stress response|global transcription regulation from Pol II promoter involved in osmotic stress response|regulation of transcription from RNA polymerase II promoter, global involved in response to osmotic stress|regulation of gene-specific transcription from RNA polymerase II promoter involved in response to osmotic stress|global transcription regulation from Pol II promoter involved in response to osmotic stress|regulation of global transcription from Pol II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter, global involved in osmotic response|regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic stress response|regulation of global transcription from Pol II promoter involved in osmotic stress response				This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0006970|GO:0006357	kmv	2013-04-01T17:24:04Z		True				biological_process											owl:Class	
GO:0072328	biolink:NamedThing	alkene binding	Binding to an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.	got7fsn_ti							mah	2010-11-02T12:39:40Z						molecular_function											owl:Class	
GO:1900955	biolink:NamedThing	positive regulation of 18-methylnonadec-1-ene metabolic process	Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.	got7fsn_ti	activation of 18-methylnonadec-1-ene metabolism|up regulation of 18-methylnonadec-1-ene metabolic process|up-regulation of 18-methylnonadec-1-ene metabolic process|positive regulation of 18-methylnonadec-1-ene metabolism|upregulation of 18-methylnonadec-1-ene metabolism|upregulation of 18-methylnonadec-1-ene metabolic process|up-regulation of 18-methylnonadec-1-ene metabolism|up regulation of 18-methylnonadec-1-ene metabolism|activation of 18-methylnonadec-1-ene metabolic process						tt	2012-06-14T03:25:44Z						biological_process											owl:Class	
GO:1900622	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling	Calcium-mediated signaling that results in positive regulation of transcription from an RNA polymerase II promoter.	got7fsn_ti	up regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|activation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|calcineurin-dependent transcription activation|upregulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|up regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|up-regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|up-regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|activation of transcription from RNA polymerase II promoter by calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|positive regulation of transcription from Pol II promoter by calcium-mediated signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling|stimulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|upregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|calcineurin-mediated activation of transcription|positive regulation of global transcription from Pol II promoter by calcium-mediated signaling|positive regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling|calcineurin-dependent transcriptional induction						bf	2012-05-18T01:01:04Z						biological_process											owl:Class	
GO:0005647	biolink:NamedThing	obsolete importin, alpha-subunit	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	importin, alpha-subunit|karyopherin-alpha				This term was made obsolete because it represents a single gene product and not a complex.	GO:0017056|GO:0005634|GO:0005643|GO:0005737				True				cellular_component											owl:Class	
GO:0050949	biolink:NamedThing	negative regulation of late stripe melanocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation.	got7fsn_ti	down-regulation of late stripe melanocyte differentiation|negative regulation of late stripe melanophore differentiation|inhibition of late stripe melanocyte differentiation|downregulation of late stripe melanocyte differentiation|down regulation of late stripe melanocyte differentiation													biological_process											owl:Class	
GO:0071767	biolink:NamedThing	mycolic acid metabolic process	The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.	got7fsn_ti	mycolic acid metabolism|mycolate metabolic process						mah	2010-03-29T04:33:31Z						biological_process											owl:Class	
GO:0005396	biolink:NamedThing	obsolete transmembrane conductance regulator activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transmembrane conductance regulator activity				This term was made obsolete because its meaning was ambiguous, it was undefined and its position in the tree wrong.	GO:0043267				True				molecular_function											owl:Class	
GO:0030382	biolink:NamedThing	sperm mitochondrion organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.	got7fsn_ti	sperm mitochondrion organization and biogenesis|sperm mitochondria organisation|sperm mitochondria organization and biogenesis													biological_process											owl:Class	
GO:0075162	biolink:NamedThing	obsolete regulation of G-protein beta subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0019936	biolink:NamedThing	obsolete inositol phospholipid-mediated signaling	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	inositol phospholipid-mediated signalling|inositol phospholipid-mediated signaling				This term was made obsolete because it did not adequately describe phosphoinositide-mediated signaling.	GO:0048017|GO:0048016				True				biological_process											owl:Class	
GO:1904792	biolink:NamedThing	positive regulation of shelterin complex assembly	Any process that activates or increases the frequency, rate or extent of shelterin complex assembly.	got7fsn_ti	activation of Pot1 complex assembly|up-regulation of Pot1-Tpz1 complex assembly|positive regulation of telosome assembly|upregulation of telosome assembly|up-regulation of Pot1 complex assembly|positive regulation of Pot1-Tpz1 complex assembly|upregulation of shelterin complex formation|activation of telosome assembly|up regulation of shelterin complex formation|up regulation of Pot1-Tpz1 complex assembly|up regulation of Pot1 complex assembly|activation of Pot1-Tpz1 complex assembly|positive regulation of Pot1 complex assembly|activation of shelterin complex formation|positive regulation of shelterin complex formation|upregulation of Pot1-Tpz1 complex assembly|upregulation of Pot1 complex assembly|up regulation of telosome assembly|up-regulation of telosome assembly|up-regulation of shelterin complex formation						nc	2015-11-06T16:13:18Z						biological_process											owl:Class	
GO:0051727	biolink:NamedThing	obsolete cell cycle switching, meiotic to mitotic cell cycle	OBSOLETE. The process in which a cell switches cell cycle mode from meiotic to mitotic division.	got7fsn_ti	mitotic entry|initiation of mitotic cell cycle|initiation of mitosis|entry into mitotic cell cycle|cell cycle switching, meiosis to mitosis|cell cycle switching, meiotic to mitotic cell cycle|entry into mitosis|conversion to mitosis|conversion to mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.					True				biological_process											owl:Class	
GO:0023009	biolink:NamedThing	obsolete initiation of T cell receptor signaling	OBSOLETE. The process in which a signal causes activation of T cell receptor signaling.	got7fsn_ti	initiation of T cell receptor signaling|initiation of T cell receptor signalling				This term was made obsolete because the meaning of the term is ambiguous.	GO:0042101|GO:0048018|GO:0050852|GO:0038023		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0008014	biolink:NamedThing	obsolete calcium-dependent cell adhesion molecule activity	OBSOLETE. A calcium-dependent cell adhesion protein (type I membrane protein) that interacts in a homophilic manner in cell-cell interactions.	got7fsn_ti	calcium-dependent cell adhesion molecule activity|cadherin				This term was made obsolete because it represents a gene product.	GO:0016021|GO:0016339|GO:0005515				True	GO:0001538			molecular_function											owl:Class	
GO:2001064	biolink:NamedThing	cellooligosaccharide binding	Binding to cellooligosaccharide.	got7fsn_ti							jl	2011-09-14T10:32:19Z						molecular_function											owl:Class	
GO:0070795	biolink:NamedThing	positive regulation of conidiophore development	Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.	got7fsn_ti							mah	2009-07-08T03:08:29Z						biological_process											owl:Class	
GO:0032539	biolink:NamedThing	negative regulation of host-seeking behavior	Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism.	got7fsn_ti	down-regulation of host-seeking behavior|down regulation of host-seeking behavior|negative regulation of host-seeking behaviour|inhibition of host-seeking behavior|downregulation of host-seeking behavior													biological_process											owl:Class	
GO:0004186	biolink:NamedThing	obsolete carboxypeptidase C activity	OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity.	got7fsn_ti	carboxypeptidase Y activity|serine carboxypeptidase I activity|deamidase|vacuolar carboxypeptidase Y|carboxypeptidase C activity|lysosomal carboxypeptidase A|lysosomal protective protein activity|cathepsin A activity|serine-type carboxypeptidase I activity			GO:0004185	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
UBERON:0003903	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901144	biolink:NamedThing	obsolete insulin biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of insulin.	got7fsn_ti	insulin biosynthesis|insulin anabolism|insulin synthesis|insulin formation|insulin biosynthetic process						pm	2012-07-13T12:33:10Z		True				biological_process											owl:Class	
GO:2000307	biolink:NamedThing	regulation of tumor necrosis factor (ligand) superfamily member 11 production	Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.	got7fsn_ti	regulation of TNFSF11 production|regulation of RANKL production						mah	2011-01-17T10:44:00Z						biological_process											owl:Class	
GO:0004284	biolink:NamedThing	obsolete acrosin activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa > Lys-Xaa.	got7fsn_ti	psi-acrosin|beta-acrosin|acrosomal protease activity|acrozonase activity|acrosin activity|alpha-acrosin|acrosin amidase activity|acrosomal proteinase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0090180	biolink:NamedThing	positive regulation of thiamine biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.	got7fsn_ti	positive regulation of thiamin biosynthetic process						tb	2009-12-18T10:30:07Z						biological_process											owl:Class	
GO:1905821	biolink:NamedThing	positive regulation of chromosome condensation	Any process that activates or increases the frequency, rate or extent of chromosome condensation.	got7fsn_ti	up regulation of nuclear chromosome condensation|activation of chromosome condensation|up-regulation of chromosome condensation|up regulation of chromosome condensation|positive regulation of nuclear chromosome condensation|positive regulation of eukaryotic chromosome condensation|up-regulation of nuclear chromosome condensation|upregulation of eukaryotic chromosome condensation|activation of nuclear chromosome condensation|upregulation of nuclear chromosome condensation|up-regulation of eukaryotic chromosome condensation|activation of eukaryotic chromosome condensation|up regulation of eukaryotic chromosome condensation|upregulation of chromosome condensation						bhm	2017-01-13T14:13:44Z						biological_process											owl:Class	
GO:1905430	biolink:NamedThing	cellular response to glycine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.	got7fsn_ti	cellular response to aminoethanoic acid|cellular response to glycin|cellular response to Gly|cellular response to aminoacetic acid						sl	2016-09-08T22:09:23Z						biological_process											owl:Class	
GO:0046342	biolink:NamedThing	CDP-diacylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.	got7fsn_ti	CDP-diacylglycerol degradation|CDP-diacylglycerol catabolism|CDP-diacylglycerol breakdown													biological_process											owl:Class	
GO:0016220	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005107	biolink:NamedThing	obsolete GPI-linked ephrin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	GPI-linked ephrin				This term was made obsolete because it refers to a class of gene products.	GO:0046658|GO:0046875				True				molecular_function											owl:Class	
GO:0035306	biolink:NamedThing	positive regulation of dephosphorylation	Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.	got7fsn_ti	upregulation of dephosphorylation|stimulation of dephosphorylation|activation of dephosphorylation|up-regulation of dephosphorylation|up regulation of dephosphorylation													biological_process											owl:Class	
GO:0010516	biolink:NamedThing	negative regulation of cellular response to nitrogen starvation	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.	got7fsn_ti														biological_process											owl:Class	
GO:1990093	biolink:NamedThing	obsolete negative regulation of N-methyl-D-aspartate receptor clustering	OBSOLETE. The negative regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.	got7fsn_ti	negative regulation of NMDA receptor clustering|negative regulation of N-methyl-D-aspartate receptor clustering				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2013-05-06T17:39:44Z		True				biological_process											owl:Class	
GO:1904702	biolink:NamedThing	regulation of protein localization to adherens junction	Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	got7fsn_ti	regulation of protein localisation in cell-cell adherens junction|regulation of protein localization in cell-cell adherens junction|regulation of protein localisation to cell-cell adherens junction						kmv	2015-10-01T15:11:49Z						biological_process											owl:Class	
GO:2001120	biolink:NamedThing	methanofuran biosynthetic process	The chemical reactions and pathways resulting in the formation of a methanofuran.	got7fsn_ti	methanofuran biosynthesis						jl	2011-10-11T12:34:12Z						biological_process											owl:Class	
GO:2000592	biolink:NamedThing	regulation of metanephric DCT cell differentiation	Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation.	got7fsn_ti	regulation of metanephric distal convoluted tubule cell differentiation						yaf	2011-04-11T01:40:33Z						biological_process											owl:Class	
GO:1905160	biolink:NamedThing	obsolete positive regulation of Factor XII activation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of Factor XII activation.	got7fsn_ti	upregulation of Factor XII activation|activation of Hageman factor activation|activation of Factor XII activation|up regulation of Factor XII activation|up regulation of Hageman factor activation|up-regulation of Factor XII activation|up-regulation of Hageman factor activation|upregulation of Hageman factor activation|positive regulation of Hageman factor activation				This term was accidentally approved after TermGenie review.  It should not have been approved.		sl	2016-04-19T23:03:43Z		True				biological_process											owl:Class	
GO:1902045	biolink:NamedThing	negative regulation of Fas signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.	got7fsn_ti	inhibition of Fas signaling pathway|inhibition of FAS ligand-Fas signaling pathway|down-regulation of Fas-FasL signaling pathway|down regulation of FasL signaling pathway|downregulation of FasR signaling pathway|downregulation of Fas receptor signaling pathway|negative regulation of Fas-FasL signaling pathway|negative regulation of FasR signaling pathway|inhibition of CD95 signaling pathway|down-regulation of Apo-1 signaling pathway|down-regulation of CD95 signaling pathway|down-regulation of Fas receptor signaling pathway|downregulation of Apo-1 signaling pathway|down regulation of FAS ligand-Fas signaling pathway|downregulation of Fas signaling pathway|down-regulation of FasL signaling pathway|inhibition of FasL signaling pathway|down-regulation of FasR signaling pathway|down regulation of FasR signaling pathway|down-regulation of Fas signaling pathway|downregulation of CD95 signaling pathway|negative regulation of FasL signaling pathway|downregulation of Fas-FasL signaling pathway|negative regulation of CD95 signaling pathway|inhibition of Apo-1 signaling pathway|negative regulation of FAS ligand-Fas signaling pathway|inhibition of FasR signaling pathway|downregulation of FasL signaling pathway|down regulation of CD95 signaling pathway|down regulation of Fas receptor signaling pathway|down regulation of Apo-1 signaling pathway|negative regulation of Fas receptor signaling pathway|inhibition of Fas-FasL signaling pathway|down regulation of Fas signaling pathway|inhibition of Fas receptor signaling pathway|downregulation of FAS ligand-Fas signaling pathway|down regulation of Fas-FasL signaling pathway|negative regulation of Apo-1 signaling pathway|down-regulation of FAS ligand-Fas signaling pathway						lb	2013-04-03T07:21:28Z						biological_process											owl:Class	
GO:0042372	biolink:NamedThing	phylloquinone biosynthetic process	The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.	got7fsn_ti	phytonadione biosynthesis|phytylmenaquinone biosynthesis|phytomenadione biosynthetic process|phylloquinone anabolism|phylloquinone formation|phylloquinone synthesis|vitamin K1 biosynthetic process|phytylmenaquinone biosynthetic process|vitamin K1 biosynthesis|phytomenadione biosynthesis|phylloquinone biosynthesis|phytonadione biosynthetic process											MetaCyc:PWY-5027		biological_process											owl:Class	
GO:0030214	biolink:NamedThing	hyaluronan catabolic process	The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.	got7fsn_ti	hyaluronan degradation|hyaluronan breakdown|hyaluronan catabolism													biological_process											owl:Class	
GO:0035533	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 6 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).	got7fsn_ti	positive regulation of chemokine (C-C motif) ligand 6 secretion|positive regulation of CCL6 production						bf	2010-05-07T10:24:21Z			GO:0035537			biological_process											owl:Class	
GO:1902552	biolink:NamedThing	negative regulation of catalase activity	Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity.	got7fsn_ti	down-regulation of heme catalase activity|negative regulation of manganese catalase activity|down regulation of manganese catalase activity|down-regulation of catalase activity|inhibition of optidase activity|negative regulation of catalase reaction|downregulation of CAT|down-regulation of equilase activity|downregulation of catalase activity|inhibition of haem catalase activity|down-regulation of optidase activity|downregulation of catalase-peroxidase activity|down regulation of haem catalase activity|down regulation of CAT|inhibition of caperase activity|down regulation of bacterial catalase-peroxidase activity|downregulation of manganese catalase activity|down regulation of optidase activity|down regulation of catalase activity|down regulation of heme catalase activity|downregulation of optidase activity|down regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down-regulation of catalase-peroxidase activity|downregulation of caperase activity|down regulation of caperase activity|down-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|inhibition of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|inhibition of manganese catalase activity|inhibition of catalase reaction|negative regulation of equilase activity|negative regulation of caperase activity|inhibition of heme catalase activity|inhibition of bacterial catalase-peroxidase activity|down-regulation of haem catalase activity|down regulation of equilase activity|down-regulation of caperase activity|down regulation of catalase reaction|negative regulation of CAT|downregulation of equilase activity|downregulation of bacterial catalase-peroxidase activity|down regulation of catalase-peroxidase activity|inhibition of CAT|downregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|downregulation of haem catalase activity|down-regulation of manganese catalase activity|inhibition of equilase activity|inhibition of catalase-peroxidase activity|negative regulation of optidase activity|negative regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|negative regulation of haem catalase activity|inhibition of catalase activity|downregulation of catalase reaction|down-regulation of CAT|negative regulation of bacterial catalase-peroxidase activity|negative regulation of heme catalase activity|down-regulation of catalase reaction|down-regulation of bacterial catalase-peroxidase activity|downregulation of heme catalase activity|negative regulation of catalase-peroxidase activity						tb	2013-12-04T21:55:55Z						biological_process											owl:Class	
GO:1904351	biolink:NamedThing	negative regulation of protein catabolic process in the vacuole	Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole.	got7fsn_ti	downregulation of vacuolar protein catabolic process|downregulation of vacuolar protein degradation|inhibition of vacuolar protein breakdown|negative regulation of vacuolar protein catabolism|down regulation of protein catabolic process in the vacuole|down regulation of vacuolar protein breakdown|negative regulation of vacuolar protein breakdown|inhibition of vacuolar protein catabolism|inhibition of protein catabolic process in the vacuole|downregulation of protein catabolic process in the vacuole|negative regulation of vacuolar protein catabolic process|down regulation of vacuolar protein catabolic process|downregulation of vacuolar protein breakdown|inhibition of vacuolar protein catabolic process|down-regulation of vacuolar protein breakdown|negative regulation of vacuolar protein degradation|down-regulation of vacuolar protein catabolic process|down-regulation of vacuolar protein catabolism|down-regulation of vacuolar protein degradation|down regulation of vacuolar protein catabolism|downregulation of vacuolar protein catabolism|down regulation of vacuolar protein degradation|down-regulation of protein catabolic process in the vacuole|inhibition of vacuolar protein degradation						rl	2015-06-12T09:10:42Z						biological_process											owl:Class	
GO:0001089	biolink:NamedThing	obsolete transcription factor activity, TFIIF-class transcription factor binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIF class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	got7fsn_ti	TFIIF-class binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001096	krc	2010-10-28T02:27:12Z		True				molecular_function											owl:Class	
GO:1901116	biolink:NamedThing	cephamycin C metabolic process	The chemical reactions and pathways involving cephamycin C.	got7fsn_ti	cephamycin C metabolism						yaf	2012-07-11T03:06:51Z						biological_process											owl:Class	
GO:0071520	biolink:NamedThing	actomyosin contractile ring assembly actin filament bundle convergence	A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring.	got7fsn_ti	actin filament bundle convergence involved in actomyosin contractile ring formation|actin filament bundle convergence involved in cytokinetic actomyosin contractile ring assembly						mah	2010-01-06T05:33:16Z						biological_process											owl:Class	
GO:0061432	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to methionine	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a methionine stimulus.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357	dph	2012-02-07T10:33:35Z		True				biological_process											owl:Class	
GO:1900433	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to heat	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.	got7fsn_ti	upregulation of filamentous growth of a population of unicellular organisms in response to heat|activation of filamentous growth of a population of unicellular organisms in response to heat|up regulation of filamentous growth of a population of unicellular organisms in response to heat|up-regulation of filamentous growth of a population of unicellular organisms in response to heat						di	2012-04-25T05:54:23Z						biological_process											owl:Class	
GO:1903656	biolink:NamedThing	regulation of type IV pilus biogenesis	Any process that modulates the frequency, rate or extent of type IV pilus biogenesis.	got7fsn_ti	regulation of type IV pilus biosynthesis|regulation of type IV fimbrial assembly|regulation of type IV fimbrium biogenesis|regulation of TFP biogenesis|regulation of type IV fimbrium assembly|regulation of type IV fimbrial biogenesis|regulation of type IV fimbria biogenesis|regulation of type IV fimbriae assembly|regulation of type IV fimbriae biogenesis|regulation of type IV fimbria assembly|regulation of type 4 pilus biogenesis						jl	2014-11-25T12:03:09Z						biological_process											owl:Class	
GO:0004216	biolink:NamedThing	obsolete cathepsin K activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Has a broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg.	got7fsn_ti	cathepsin K activity|cathepsin O2 activity|cathepsin O activity|cathepsin X activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0042954	biolink:NamedThing	obsolete lipoprotein transporter activity	OBSOLETE. Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17004			The reason for obsoletion is this term has been incorrectly used.					True				molecular_function											owl:Class	
GO:0100046	biolink:NamedThing	obsolete positive regulation of arginine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates arginine biosynthetic process.	got7fsn_ti					GO:0100046		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1905803	biolink:NamedThing	negative regulation of cellular response to manganese ion	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion.	got7fsn_ti	down-regulation of cellular response to manganese|downregulation of cellular response to manganese|down regulation of cellular response to manganese ion|down-regulation of cellular response to manganese ion|down regulation of cellular response to manganese|downregulation of cellular response to manganese ion|inhibition of cellular response to manganese ion|inhibition of cellular response to manganese|negative regulation of cellular response to manganese						pga	2017-01-11T14:59:48Z						biological_process											owl:Class	
GO:0004203	biolink:NamedThing	obsolete caspase-4 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	caspase-4 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0071996	biolink:NamedThing	glutathione transmembrane import into vacuole	The directed movement of glutathione into the vacuole across the vacuolar membrane.	got7fsn_ti	glutathione transport into vacuole						mah	2010-10-25T02:12:01Z						biological_process											owl:Class	
GO:0002058	biolink:NamedThing	uracil binding	Binding to uracil.	got7fsn_ti														molecular_function											owl:Class	
GO:1902631	biolink:NamedThing	negative regulation of membrane hyperpolarization	Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization.	got7fsn_ti	downregulation of membrane hyperpolarization|down-regulation of membrane hyperpolarization|down regulation of membrane hyperpolarization|inhibition of membrane hyperpolarization						krc	2014-01-17T18:28:05Z						biological_process											owl:Class	
GO:0006377	biolink:NamedThing	obsolete MATa1 (A1) pre-mRNA splicing	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	MATa1 (A1) pre-mRNA splicing				This term was made obsolete because it does not represent a process unique to splicing of the MATa1 (A1) pre-mRNA, but a recycling defect exacerbated by the presence of two introns within the same gene.	GO:0000244				True				biological_process											owl:Class	
GO:0002092	biolink:NamedThing	positive regulation of receptor internalization	Any process that activates or increases the frequency, rate or extent of receptor internalization.	got7fsn_ti	stimulation of receptor internalization|up regulation of receptor internalization|up-regulation of receptor internalization|upregulation of receptor internalization|activation of receptor internalization													biological_process											owl:Class	
GO:0015470	biolink:NamedThing	obsolete bacteriocin activity	OBSOLETE. Polypeptide antibiotic secreted by bacteria and able to kill bacteria of susceptible strains after absorption by specific cell surface receptor.	got7fsn_ti	bacteriocin activity				This term was made obsolete because it represents a gene product.	GO:0019835|GO:0005102				True				molecular_function											owl:Class	
GO:0034241	biolink:NamedThing	positive regulation of macrophage fusion	Any process that activates or increases the frequency, rate or extent of macrophage fusion.	got7fsn_ti														biological_process											owl:Class	
GO:1901578	biolink:NamedThing	negative regulation of alkane biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process.	got7fsn_ti	down-regulation of alkane biosynthesis|downregulation of alkane biosynthesis|downregulation of alkane synthesis|negative regulation of alkane anabolism|negative regulation of alkane formation|downregulation of alkane biosynthetic process|downregulation of alkane anabolism|down-regulation of alkane biosynthetic process|down-regulation of alkane formation|down regulation of alkane formation|inhibition of alkane anabolism|inhibition of alkane biosynthetic process|down-regulation of alkane anabolism|downregulation of alkane formation|inhibition of alkane biosynthesis|negative regulation of alkane biosynthesis|down regulation of alkane biosynthetic process|inhibition of alkane formation|inhibition of alkane synthesis|negative regulation of alkane synthesis|down regulation of alkane anabolism|down regulation of alkane biosynthesis|down regulation of alkane synthesis|down-regulation of alkane synthesis						dhl	2012-11-05T21:54:11Z						biological_process											owl:Class	
GO:0004433	biolink:NamedThing	obsolete 1-phosphatidylinositol-4-phosphate kinase, class IB	OBSOLETE. A class I PI3K activated via heterotrimeric G-proteins.	got7fsn_ti	1-phosphatidylinositol-4-phosphate kinase, class IB				This term was made obsolete because it is not a valid molecular function.	GO:0016308				True				molecular_function											owl:Class	
GO:0019525	biolink:NamedThing	keto-D-gluconate metabolic process	The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.	got7fsn_ti	keto-D-gluconate metabolism													biological_process											owl:Class	
GO:1900998	biolink:NamedThing	nitrobenzene catabolic process	The chemical reactions and pathways resulting in the breakdown of nitrobenzene.	got7fsn_ti	nitrobenzene catabolism|nitrobenzene breakdown|nitrobenzene degradation						yaf	2012-06-14T02:54:09Z						biological_process											owl:Class	
GO:0070402	biolink:NamedThing	NADPH binding	Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.	got7fsn_ti	reduced NADP binding|NADP (reduced) binding|reduced nicotinamide adenine dinucleotide phosphate binding													molecular_function											owl:Class	
GO:2000091	biolink:NamedThing	negative regulation of mesonephric glomerular mesangial cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.	got7fsn_ti							dph	2010-09-03T06:10:31Z						biological_process											owl:Class	
GO:1905645	biolink:NamedThing	negative regulation of FACT complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly.	got7fsn_ti	downregulation of FACT complex formation|inhibition of Facilitates chromatin transcription complex formation|inhibition of Facilitates chromatin transcription complex assembly|negative regulation of Facilitates chromatin transcription complex assembly|down regulation of Facilitates chromatin transcription complex formation|down-regulation of FACT complex assembly|negative regulation of FACT complex formation|inhibition of FACT complex formation|inhibition of FACT complex assembly|down regulation of Facilitates chromatin transcription complex assembly|down regulation of FACT complex formation|down-regulation of FACT complex formation|downregulation of Facilitates chromatin transcription complex assembly|down regulation of FACT complex assembly|downregulation of Facilitates chromatin transcription complex formation|down-regulation of Facilitates chromatin transcription complex assembly|down-regulation of Facilitates chromatin transcription complex formation|negative regulation of Facilitates chromatin transcription complex formation|downregulation of FACT complex assembly						pga	2016-11-07T09:14:13Z						biological_process											owl:Class	
GO:0015532	biolink:NamedThing	alpha-ketoglutarate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in).	got7fsn_ti	alpha-ketoglutarate:hydrogen symporter activity|2-oxoglutarate:hydrogen symporter activity|2-oxoglutarate:proton symporter activity													molecular_function											owl:Class	
GO:0075161	biolink:NamedThing	obsolete negative regulation of G-protein alpha subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:2000370	biolink:NamedThing	positive regulation of clathrin-dependent endocytosis	Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.	got7fsn_ti	positive regulation of clathrin-dependent endocytosis|positive regulation of clathrin-mediated endocytosis|positive regulation of clathrin coated pit-dependent endocytosis						mah	2011-02-09T12:36:28Z						biological_process											owl:Class	
GO:1900139	biolink:NamedThing	negative regulation of arachidonic acid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.	got7fsn_ti	downregulation of arachidonic acid secretion|down regulation of arachidonic acid secretion|down-regulation of arachidonic acid secretion|inhibition of arachidonic acid secretion						rph	2012-03-01T09:21:19Z						biological_process											owl:Class	
GO:0043064	biolink:NamedThing	obsolete flagellum organization	OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum, a long thin projection from a cell, used in movement.	got7fsn_ti	flagellum organization and biogenesis|flagellum organisation|flagellum organization				This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:0044782|GO:0044781				True				biological_process											owl:Class	
GO:0045558	biolink:NamedThing	obsolete TRAIL receptor 1 biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of TRAIL-R1 (TNF-related apoptosis inducing ligand receptor 1), which engages a caspase-dependent apoptotic pathway.	got7fsn_ti	tumor necrosis factor receptor superfamily member 10A biosynthetic process|TRAIL receptor 1 biosynthesis|TRAIL receptor 1 synthesis|TRAIL receptor 1 anabolism|TRAIL receptor 1 formation	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0006129	biolink:NamedThing	obsolete protein-disulfide reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	protein-disulphide reduction|protein-disulfide reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0022900|GO:0019153				True				biological_process											owl:Class	
GO:0071264	biolink:NamedThing	positive regulation of translational initiation in response to starvation	Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.	got7fsn_ti	up regulation of translation initiation in response to starvation|activation of translation initiation in response to starvation|upregulation of translation initiation in response to starvation|positive regulation of translational initiation in response to nutrient starvation|up-regulation of translation initiation in response to starvation|stimulation of translation initiation in response to starvation						mah	2009-12-08T05:35:45Z						biological_process											owl:Class	
GO:0008189	biolink:NamedThing	obsolete apoptosis inhibitor activity	OBSOLETE. The function held by products which directly block any step in the process of apoptosis.	got7fsn_ti	apoptosis inhibitor activity			GO:0043066	This term was made obsolete because it represents involvement in a biological process.					True				molecular_function											owl:Class	
GO:0044330	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of wound healing	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in positive regulation of wound healing.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in positive regulation of wound healing|canonical Wnt receptor signaling pathway involved in positive regulation of wound healing|canonical Wnt-activated signaling pathway involved in positive regulation of wound healing						jl	2010-08-18T04:21:21Z						biological_process											owl:Class	
GO:0045723	biolink:NamedThing	positive regulation of fatty acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.	got7fsn_ti	positive regulation of fatty acid biosynthesis|stimulation of fatty acid biosynthetic process|positive regulation of fatty acid formation|activation of fatty acid biosynthetic process|positive regulation of fatty acid anabolism|positive regulation of fatty acid synthesis|up regulation of fatty acid biosynthetic process|upregulation of fatty acid biosynthetic process|up-regulation of fatty acid biosynthetic process													biological_process											owl:Class	
GO:1901856	biolink:NamedThing	negative regulation of cellular respiration	Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.	got7fsn_ti	down-regulation of cellular respiration|down regulation of respiration|negative regulation of oxidative metabolic process|down-regulation of respiration|inhibition of oxidative metabolism|inhibition of oxidative metabolic process|down-regulation of oxidative metabolic process|down-regulation of oxidative metabolism|negative regulation of oxidative metabolism|downregulation of oxidative metabolic process|downregulation of respiration|inhibition of cellular respiration|down regulation of oxidative metabolism|down regulation of cellular respiration|downregulation of oxidative metabolism|inhibition of respiration|downregulation of cellular respiration|down regulation of oxidative metabolic process|negative regulation of respiration						yaf	2013-02-01T09:56:23Z						biological_process											owl:Class	
GO:0051001	biolink:NamedThing	negative regulation of nitric-oxide synthase activity	Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.	got7fsn_ti	down-regulation of nitric-oxide synthase activity|negative regulation of NOS activity|inhibition of nitric-oxide synthase activity|downregulation of nitric-oxide synthase activity|NOS inhibitor|down regulation of nitric-oxide synthase activity|nitric-oxide synthase inhibitor													biological_process											owl:Class	
GO:1904744	biolink:NamedThing	positive regulation of telomeric DNA binding	Any process that activates or increases the frequency, rate or extent of telomeric DNA binding.	got7fsn_ti	upregulation of telomeric repeat binding|up-regulation of telomere binding|up regulation of telomeric DNA binding|activation of telomere binding|activation of telomeric repeat binding|positive regulation of telomere binding|upregulation of telomeric DNA binding|up-regulation of telomeric DNA binding|activation of telomeric DNA binding|up regulation of telomeric repeat binding|up-regulation of telomeric repeat binding|up regulation of telomere binding|upregulation of telomere binding|positive regulation of telomeric repeat binding						nc	2015-10-19T12:19:01Z						biological_process											owl:Class	
GO:0018512	biolink:NamedThing	obsolete 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity	OBSOLETE. Catalysis of the reaction: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH + H+.	got7fsn_ti	1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity|1,2-dihydroxy-3-methylcyclohexa-3,5-diene-carboxylate dehydrogenase activity				This term was made obsolete because, according to the Enzyme Commission, there is no evidence that this enzymatic activity exists.					True		UM-BBD_reactionID:r0216		molecular_function											owl:Class	
GO:0050944	biolink:NamedThing	negative regulation of xanthophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation.	got7fsn_ti	inhibition of xanthophore differentiation|downregulation of xanthophore differentiation|down-regulation of xanthophore differentiation|down regulation of xanthophore differentiation				Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure.									biological_process											owl:Class	
GO:0090074	biolink:NamedThing	negative regulation of protein homodimerization activity	Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.	got7fsn_ti							tb	2009-09-11T11:15:40Z						biological_process											owl:Class	
GO:0070794	biolink:NamedThing	negative regulation of conidiophore development	Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.	got7fsn_ti							mah	2009-07-08T03:06:48Z						biological_process											owl:Class	
GO:2000725	biolink:NamedThing	regulation of cardiac muscle cell differentiation	Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation.	got7fsn_ti	regulation of heart muscle cell differentiation|regulation of cardiomyocyte differentiation						vk	2011-06-08T10:51:06Z						biological_process											owl:Class	
GO:0019765	biolink:NamedThing	obsolete low affinity Fc receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	low affinity Fc receptor activity				This term was made obsolete because it is undefined and is an unnecessary grouping term.	GO:0019772|GO:0019769				True				molecular_function											owl:Class	
GO:1900317	biolink:NamedThing	positive regulation of maltopentaose transport	Any process that activates or increases the frequency, rate or extent of maltopentaose transport.	got7fsn_ti	up regulation of maltopentaose transport|up-regulation of maltopentaose transport|activation of maltopentaose transport|upregulation of maltopentaose transport						tt	2012-04-05T08:00:04Z						biological_process											owl:Class	
GO:0031341	biolink:NamedThing	regulation of cell killing	Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.	got7fsn_ti														biological_process											owl:Class	
GO:0007230	biolink:NamedThing	obsolete calcium-o-sensing receptor pathway	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	calcium-o-sensing receptor pathway				This term was made obsolete because it does not make sense.	GO:0019722				True				biological_process											owl:Class	
GO:1902091	biolink:NamedThing	negative regulation of fumagillin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process.	got7fsn_ti	inhibition of fumagillin synthesis|negative regulation of fumagillin synthesis|inhibition of fumagillin formation|negative regulation of fumagillin anabolism|downregulation of fumagillin anabolism|down regulation of fumagillin formation|down-regulation of fumagillin synthesis|down-regulation of fumagillin formation|down-regulation of fumagillin biosynthesis|down regulation of fumagillin anabolism|down-regulation of fumagillin anabolism|down regulation of fumagillin synthesis|downregulation of fumagillin synthesis|negative regulation of fumagillin biosynthesis|negative regulation of fumagillin formation|inhibition of fumagillin biosynthesis|down regulation of fumagillin biosynthetic process|downregulation of fumagillin biosynthetic process|downregulation of fumagillin formation|inhibition of fumagillin anabolism|down regulation of fumagillin biosynthesis|down-regulation of fumagillin biosynthetic process|inhibition of fumagillin biosynthetic process|downregulation of fumagillin biosynthesis						di	2013-04-27T03:45:04Z						biological_process											owl:Class	
GO:0060705	biolink:NamedThing	neuron differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.	got7fsn_ti							dph	2009-06-09T09:35:52Z						biological_process											owl:Class	
GO:0004240	biolink:NamedThing	obsolete mitochondrial processing peptidase activity	OBSOLETE. Catalysis of the release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.	got7fsn_ti	matrix processing peptidase|mitochondrial processing peptidase activity|mitochondrial protein precursor-processing proteinase activity|alpha-mitochondrial processing peptidase|beta-mitochondrial processing peptidase|MPP|processing enhancing peptidase activity|matrix peptidase|matrix processing proteinase|processing enhancing peptidase (for one of two subunits)			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1903893	biolink:NamedThing	positive regulation of ATF6-mediated unfolded protein response	Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response.	got7fsn_ti	up regulation of ATF6 branch of UPR|up-regulation of activating transcription factor 6 signaling in unfolded protein response|up regulation of UPR signaling by ATF6 stress sensor|up regulation of ATF6-mediated unfolded protein response|upregulation of ATF6 branch of UPR|up-regulation of ATF6-beta UPR branch|up regulation of ATF6 signaling in response to endoplasmic reticulum stress|positive regulation of ATF6-beta UPR branch|up-regulation of ATF6-alpha UPR branch|activation of ATF6-alpha UPR branch|positive regulation of ATF6-alpha UPR branch|up regulation of ATF6-alpha UPR branch|upregulation of UPR signaling by ATF6 stress sensor|positive regulation of ATF6 signaling in response to endoplasmic reticulum stress|positive regulation of ATF6 branch of UPR|upregulation of ATF6-beta UPR branch|up-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|up-regulation of ATF6 branch of UPR|activation of ATF6-mediated unfolded protein response|activation of ATF6 branch of UPR|positive regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|upregulation of ATF6-alpha UPR branch|activation of ATF6-beta UPR branch|up-regulation of UPR signaling by ATF6 stress sensor|up regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|upregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|upregulation of ATF6-mediated unfolded protein response|upregulation of ATF6 signaling in response to endoplasmic reticulum stress|up-regulation of ATF6 signaling in response to endoplasmic reticulum stress|up regulation of activating transcription factor 6 signaling in unfolded protein response|upregulation of activating transcription factor 6 signaling in unfolded protein response|activation of activating transcription factor 6 signaling in unfolded protein response|up regulation of ATF6-beta UPR branch|activation of ATF6 signaling in response to endoplasmic reticulum stress|positive regulation of UPR signaling by ATF6 stress sensor|positive regulation of activating transcription factor 6 signaling in unfolded protein response|activation of endoplasmic reticulum unfolded protein response; ATF6 signaling|activation of UPR signaling by ATF6 stress sensor|up-regulation of ATF6-mediated unfolded protein response						bf	2015-02-09T10:17:36Z						biological_process											owl:Class	
GO:1900088	biolink:NamedThing	regulation of inositol biosynthetic process	Any process that modulates the frequency, rate or extent of inositol biosynthetic process.	got7fsn_ti	regulation of inositol anabolism|regulation of vitamin Bh biosynthetic process|regulation of inositol formation|regulation of vitamin Bh biosynthesis|regulation of inositol synthesis|regulation of myo-inositol biosynthesis|regulation of myo-inositol biosynthetic process|regulation of inositol biosynthesis						dhl	2012-02-08T06:27:11Z						biological_process											owl:Class	
GO:1900004	biolink:NamedThing	negative regulation of serine-type endopeptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity.	got7fsn_ti	down regulation of blood coagulation factor activity|negative regulation of blood coagulation factor activity|down regulation of serine-type endopeptidase activity						kmv	2012-01-09T10:03:20Z						biological_process											owl:Class	
GO:1905474	biolink:NamedThing	canonical Wnt signaling pathway involved in stem cell proliferation	Any canonical Wnt signaling pathway that is involved in stem cell proliferation.	got7fsn_ti	Wnt receptor signaling pathway via beta-catenin involved in stem cell proliferation|frizzled-1 receptor signaling pathway involved in stem cell proliferation|canonical Wnt receptor signaling pathway involved in stem cell proliferation|canonical Wnt-activated signaling pathway involved in stem cell proliferation|Wnt receptor signaling pathway through beta-catenin involved in stem cell proliferation|Wnt receptor signalling pathway through beta-catenin involved in stem cell proliferation						bc	2016-09-21T15:59:53Z						biological_process											owl:Class	
GO:0060475	biolink:NamedThing	positive regulation of actin filament polymerization involved in acrosome reaction	Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction.	got7fsn_ti	positive regulation of actin polymerization involved in acrosome reaction													biological_process											owl:Class	
GO:1903209	biolink:NamedThing	positive regulation of oxidative stress-induced cell death	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced cell death.	got7fsn_ti	positive regulation of cell death in response to oxidative stress|upregulation of cell death in response to oxidative stress|activation of cell death in response to oxidative stress|up regulation of cell death in response to oxidative stress|enhancement of oxidative stress-induced cell death|up-regulation of cell death in response to oxidative stress						bf	2014-07-22T09:32:19Z						biological_process											owl:Class	
GO:0032485	biolink:NamedThing	regulation of Ral protein signal transduction	Any process that modulates the frequency, rate or extent of Ral protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:0008648	biolink:NamedThing	obsolete tachykinin	OBSOLETE. A family of hormones that stimulate secretion of saliva and cause smooth muscle contraction and vasodilation.	got7fsn_ti	tachykinin				This term was made obsolete because it represents a gene product.	GO:0042311|GO:0005102|GO:0045987|GO:0046878				True				molecular_function											owl:Class	
GO:1900388	biolink:NamedThing	obsolete regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of vesicle-mediated transport.	got7fsn_ti	regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter				This term was made obsolete because there is no evidence that vesicle-mediated transport is regulated transcriptionally.		mah	2012-04-18T03:52:29Z		True				biological_process											owl:Class	
GO:0004183	biolink:NamedThing	obsolete carboxypeptidase E activity	OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents.	got7fsn_ti	enkephalin-precursor endopeptidase activity|cobalt-stimulated chromaffin granule carboxypeptidase activity|insulin granule-associated carboxypeptidase activity|enkephalin convertase activity|carboxypeptidase E activity|carboxypeptidase H activity|membrane-bound carboxypeptidase activity|enkephalin precursor carboxypeptidase activity|peptidyl-L-lysine(-L-arginine) hydrolase			GO:0004181	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0046456	biolink:NamedThing	icosanoid biosynthetic process	The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.	got7fsn_ti	eoxin biosynthesis|eicosanoid biosynthetic process|eoxin synthesis|icosanoid formation|icosanoid anabolism|icosanoid biosynthesis|icosanoid synthesis|eicosanoid biosynthesis	https://github.com/geneontology/go-ontology/issues/18848										Wikipedia:Eicosanoid		biological_process											owl:Class	
GO:1900185	biolink:NamedThing	positive regulation of xanthone-containing compound biosynthetic process	Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process.	got7fsn_ti	up-regulation of xanthone-containing compound formation|upregulation of xanthone biosynthesis|activation of xanthone-containing compound anabolism|up-regulation of xanthone biosynthesis|positive regulation of xanthone-containing compound formation|positive regulation of xanthone-containing compound anabolism|up-regulation of xanthone-containing compound biosynthetic process|upregulation of xanthone-containing compound biosynthesis|up-regulation of xanthone-containing compound biosynthesis|up regulation of xanthone-containing compound synthesis|up regulation of xanthone biosynthetic process|up regulation of xanthone biosynthesis|activation of xanthone-containing compound biosynthetic process|up regulation of xanthone-containing compound biosynthesis|activation of xanthone biosynthetic process|positive regulation of xanthone biosynthesis|activation of xanthone-containing compound formation|up regulation of xanthone-containing compound biosynthetic process|up regulation of xanthone-containing compound formation|upregulation of xanthone-containing compound anabolism|up-regulation of xanthone-containing compound anabolism|upregulation of xanthone-containing compound formation|up regulation of xanthone-containing compound anabolism|upregulation of xanthone-containing compound biosynthetic process|activation of xanthone biosynthesis|activation of xanthone-containing compound biosynthesis|upregulation of xanthone-containing compound synthesis|activation of xanthone-containing compound synthesis|positive regulation of xanthone biosynthetic process|up-regulation of xanthone-containing compound synthesis|positive regulation of xanthone-containing compound synthesis|positive regulation of xanthone-containing compound biosynthesis|up-regulation of xanthone biosynthetic process|upregulation of xanthone biosynthetic process						di	2012-03-16T03:30:32Z						biological_process											owl:Class	
GO:0001090	biolink:NamedThing	obsolete transcription factor activity, TFIIH-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIH class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	got7fsn_ti	TFIIH-class binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2010-10-28T02:28:01Z		True				molecular_function											owl:Class	
GO:1905241	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.	got7fsn_ti	up-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|activation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|activation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|activation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|activation of canonical Wnt signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation						rph	2016-06-08T10:26:49Z						biological_process											owl:Class	
GO:1902369	biolink:NamedThing	negative regulation of RNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.	got7fsn_ti	inhibition of RNA catabolic process|down regulation of RNA catabolism|downregulation of RNA degradation|down-regulation of RNA catabolic process|negative regulation of RNA degradation|downregulation of RNA catabolism|down-regulation of RNA degradation|down regulation of RNA degradation|inhibition of RNA breakdown|down-regulation of RNA breakdown|inhibition of RNA degradation|down-regulation of RNA catabolism|negative regulation of RNA catabolism|down regulation of RNA breakdown|negative regulation of RNA breakdown|inhibition of RNA catabolism|downregulation of RNA catabolic process|down regulation of RNA catabolic process|downregulation of RNA breakdown						bf	2013-08-22T14:59:39Z						biological_process											owl:Class	
GO:2000478	biolink:NamedThing	positive regulation of metanephric glomerular visceral epithelial cell development	Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.	got7fsn_ti	positive regulation of metanephric podocyte development						yaf	2011-03-09T05:17:26Z						biological_process											owl:Class	
GO:1903336	biolink:NamedThing	negative regulation of vacuolar transport	Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.	got7fsn_ti	inhibition of vacuolar transport|down regulation of vacuolar transport|down-regulation of vacuolar transport|downregulation of vacuolar transport						vw	2014-08-18T13:16:11Z						biological_process											owl:Class	
GO:1900654	biolink:NamedThing	positive regulation of demethylkotanin biosynthetic process	Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process.	got7fsn_ti	up-regulation of demethylkotanin biosynthesis|up-regulation of demethylkotanin biosynthetic process|up regulation of demethylkotanin anabolism|up regulation of demethylkotanin biosynthetic process|upregulation of demethylkotanin synthesis|activation of demethylkotanin anabolism|activation of demethylkotanin formation|upregulation of demethylkotanin biosynthetic process|up-regulation of demethylkotanin formation|positive regulation of demethylkotanin synthesis|positive regulation of demethylkotanin anabolism|positive regulation of demethylkotanin formation|activation of demethylkotanin biosynthesis|upregulation of demethylkotanin anabolism|up regulation of demethylkotanin formation|upregulation of demethylkotanin formation|up regulation of demethylkotanin synthesis|up-regulation of demethylkotanin synthesis|positive regulation of demethylkotanin biosynthesis|up regulation of demethylkotanin biosynthesis|upregulation of demethylkotanin biosynthesis|up-regulation of demethylkotanin anabolism|activation of demethylkotanin biosynthetic process|activation of demethylkotanin synthesis						di	2012-05-22T04:07:49Z						biological_process											owl:Class	
GO:2000735	biolink:NamedThing	positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.	got7fsn_ti	positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|positive regulation of GDNF receptor signaling pathway of ureteric bud formation|positive regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|positive regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|positive regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation						yaf	2011-06-13T11:14:46Z						biological_process											owl:Class	
GO:1900059	biolink:NamedThing	positive regulation of sulfate assimilation	Any process that activates or increases the frequency, rate or extent of sulfate assimilation.	got7fsn_ti	positive regulation of sulphate assimilation|upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|upregulation of sulfate assimilation|activation of sulfate assimilation|up regulation of sulfate assimilation|up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|up regulation of sulphate assimilation|activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|activation of sulphate assimilation|positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|upregulation of sulphate assimilation|up-regulation of sulfate assimilation|up-regulation of sulphate assimilation						dph	2012-01-25T03:14:47Z						biological_process											owl:Class	
GO:1901062	biolink:NamedThing	guaiacyl lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin.	got7fsn_ti	G-lignin catabolic process|guaiacyl lignin catabolism|guaiacyl lignin degradation|guaiacyl lignin breakdown						tt	2012-06-29T02:47:03Z						biological_process											owl:Class	
GO:0010413	biolink:NamedThing	glucuronoxylan metabolic process	The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units.	got7fsn_ti	glucuronoxylan metabolism													biological_process											owl:Class	
GO:0140131	biolink:NamedThing	positive regulation of lymphocyte chemotaxis	Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis.	got7fsn_ti							pg	2017-11-02T10:26:40Z						biological_process											owl:Class	
GO:0006253	biolink:NamedThing	dCTP catabolic process	The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate.	got7fsn_ti	dCTP degradation|dCTP breakdown|dCTP catabolism													biological_process											owl:Class	
GO:1900327	biolink:NamedThing	regulation of mannotriose transport	Any process that modulates the frequency, rate or extent of mannotriose transport.	got7fsn_ti							tt	2012-04-06T01:50:05Z						biological_process											owl:Class	
GO:1904116	biolink:NamedThing	response to vasopressin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.	got7fsn_ti							sl	2015-04-06T19:39:42Z						biological_process											owl:Class	
GO:1904068	biolink:NamedThing	G protein-coupled receptor signaling pathway involved in social behavior	Any G protein-coupled receptor signaling pathway that is involved in social behavior.	got7fsn_ti	G-protein coupled receptor protein signaling pathway involved in social behaviour|G-protein-coupled receptor protein signalling pathway involved in social behavior|G-protein-coupled receptor protein signaling pathway involved in social behaviour|GPCR signaling pathway involved in social behavior|G-protein coupled receptor protein signaling pathway involved in cooperative behavior|G-protein-coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor protein signal transduction involved in social behavior|G-protein coupled receptor signalling pathway involved in social behavior|G protein coupled receptor protein signalling pathway involved in cooperative behavior|GPCR signaling pathway involved in social behaviour|G-protein-coupled receptor protein signaling pathway involved in cooperative behavior|GPCR signalling pathway involved in social behavior|G-protein coupled receptor signaling pathway involved in social behavior|G-protein coupled receptor signalling pathway involved in cooperative behavior|G-protein coupled receptor protein signal transduction involved in cooperative behavior|GPCR signalling pathway involved in cooperative behavior|G-protein coupled receptor signaling pathway involved in cooperative behavior|G protein coupled receptor protein signalling pathway involved in social behavior|G-protein coupled receptor signalling pathway involved in social behaviour|G-protein coupled receptor protein signaling pathway involved in social behavior|G-protein-coupled receptor protein signalling pathway involved in social behaviour|G protein coupled receptor protein signaling pathway involved in social behaviour|G-protein coupled receptor protein signal transduction involved in social behaviour|GPCR signalling pathway involved in social behaviour|G protein coupled receptor protein signalling pathway involved in social behaviour|G protein coupled receptor protein signaling pathway involved in cooperative behavior|G-protein coupled receptor signaling pathway involved in social behaviour|G-protein-coupled receptor protein signalling pathway involved in cooperative behavior|G protein coupled receptor protein signaling pathway involved in social behavior|GPCR signaling pathway involved in cooperative behavior						kmv	2015-03-20T01:51:10Z						biological_process											owl:Class	
GO:1904860	biolink:NamedThing	DNA synthesis involved in mitotic DNA replication	Any DNA biosynthetic process that is involved in mitotic DNA replication.	got7fsn_ti	DNA synthesis involved in mitotic nuclear cell cycle DNA replication|DNA formation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA formation involved in DNA replication during S phase involved in mitotic cell cycle|DNA formation involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in mitotic cell cycle DNA replication|DNA formation involved in mitotic cell cycle DNA replication|DNA biosynthetic process involved in mitotic DNA replication|DNA biosynthesis involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthetic process involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA synthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in mitotic nuclear cell cycle DNA replication|DNA biosynthesis involved in mitotic cell cycle DNA replication|DNA anabolism involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA synthesis involved in DNA replication during S phase involved in mitotic cell cycle|DNA biosynthetic process involved in mitotic cell cycle DNA replication|DNA anabolism involved in mitotic nuclear cell cycle DNA replication|DNA biosynthetic process involved in DNA replication during S phase involved in mitotic cell cycle|DNA formation involved in mitotic DNA replication|DNA biosynthetic process involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthesis involved in mitotic DNA replication|DNA formation involved in mitotic nuclear cell cycle DNA replication|DNA synthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication during S phase involved in mitotic cell cycle|DNA anabolism involved in mitotic DNA replication|DNA synthesis involved in mitotic cell cycle DNA replication|DNA formation involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA synthesis involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA biosynthesis involved in mitotic nuclear cell cycle DNA replication|DNA biosynthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA anabolism involved in DNA replication during S phase involved in mitotic cell cycle						mah	2015-12-16T12:02:37Z						biological_process											owl:Class	
GO:0071458	biolink:NamedThing	integral component of cytoplasmic side of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.	got7fsn_ti	integral to cytosolic leaflet of endoplasmic reticulum membrane|integral to cytosolic side of endoplasmic reticulum membrane|integral to cytosolic side of ER membrane|integral to ER membrane, cytosolic side						mah	2009-12-17T01:43:33Z						cellular_component											owl:Class	
GO:0015332	biolink:NamedThing	obsolete leucine/valine/isoleucine permease activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	leucine/valine/isoleucine permease activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015190|GO:0015188|GO:0005304|GO:0022857				True				molecular_function											owl:Class	
GO:2000280	biolink:NamedThing	regulation of root development	Any process that modulates the frequency, rate or extent of root development.	got7fsn_ti							dhl	2010-12-08T09:30:21Z						biological_process											owl:Class	
GO:0005999	biolink:NamedThing	xylulose biosynthetic process	The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose.	got7fsn_ti	xylulose anabolism|xylulose biosynthesis|xylulose formation|xylulose synthesis													biological_process											owl:Class	
GO:0015308	biolink:NamedThing	amiloride:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out).	got7fsn_ti	amiloride:hydrogen antiporter activity													molecular_function											owl:Class	
GO:1905741	biolink:NamedThing	calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration	Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration.	got7fsn_ti	calcium ion transmembrane export from mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration|mitochondrial calcium release involved in positive regulation of presynaptic cytosolic calcium concentration						dos	2016-12-06T10:05:01Z						biological_process											owl:Class	
GO:1905634	biolink:NamedThing	regulation of protein localization to chromatin	Any process that modulates the frequency, rate or extent of protein localization to chromatin.	got7fsn_ti	regulation of protein localisation to chromatin						pga	2016-11-01T16:33:52Z						biological_process											owl:Class	
GO:0051968	biolink:NamedThing	positive regulation of synaptic transmission, glutamatergic	Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.	got7fsn_ti	activation of synaptic transmission, glutamatergic|up-regulation of synaptic transmission, glutamatergic|upregulation of synaptic transmission, glutamatergic|stimulation of synaptic transmission, glutamatergic|up regulation of synaptic transmission, glutamatergic													biological_process											owl:Class	
OBO:OBA_0000048	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901712	biolink:NamedThing	positive regulation of homoserine biosynthetic process	Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process.	got7fsn_ti	upregulation of homoserine formation|up-regulation of homoserine formation|activation of homoserine formation|up regulation of homoserine anabolism|activation of homoserine synthesis|up regulation of homoserine synthesis|up-regulation of homoserine synthesis|positive regulation of homoserine anabolism|activation of homoserine biosynthetic process|up regulation of homoserine biosynthesis|positive regulation of homoserine biosynthesis|activation of homoserine biosynthesis|up-regulation of homoserine anabolism|positive regulation of homoserine synthesis|upregulation of homoserine anabolism|up-regulation of homoserine biosynthetic process|activation of homoserine anabolism|positive regulation of homoserine formation|upregulation of homoserine synthesis|up regulation of homoserine biosynthetic process|upregulation of homoserine biosynthetic process|upregulation of homoserine biosynthesis|up regulation of homoserine formation|up-regulation of homoserine biosynthesis						mcc	2012-12-19T16:02:05Z						biological_process											owl:Class	
GO:0052175	biolink:NamedThing	obsolete metabolism by symbiont of host carbohydrate	OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:2000118	biolink:NamedThing	regulation of sodium-dependent phosphate transport	Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport.	got7fsn_ti							jl	2010-09-23T01:34:59Z						biological_process											owl:Class	
CHEBI:17650	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019362	biolink:NamedThing	pyridine nucleotide metabolic process	The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.	got7fsn_ti	pyridine nucleotide metabolism													biological_process											owl:Class	
GO:0019305	biolink:NamedThing	dTDP-rhamnose biosynthetic process	The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.	got7fsn_ti	dTDP-rhamnose formation|dTDP-rhamnose anabolism|dTDP-rhamnose synthesis|dTDP-rhamnose biosynthesis											MetaCyc:PWY-3221|MetaCyc:DTDPRHAMSYN-PWY		biological_process											owl:Class	
GO:1901650	biolink:NamedThing	positive regulation of actomyosin contractile ring localization	Any process that activates or increases the frequency, rate or extent of actomyosin contractile ring localization.	got7fsn_ti	up regulation of contractile ring localisation involved in cell cycle cytokinesis|activation of contractile ring localisation involved in cell cycle cytokinesis|activation of actomyosin contractile ring localization|upregulation of contractile ring localization involved in cell cycle cytokinesis|up-regulation of actomyosin contractile ring localization|activation of contractile ring localization involved in cell cycle cytokinesis|up-regulation of contractile ring localization involved in cell cycle cytokinesis|positive regulation of contractile ring localisation involved in cell cycle cytokinesis|up regulation of actomyosin contractile ring localization|up-regulation of contractile ring localisation involved in cell cycle cytokinesis|upregulation of contractile ring localisation involved in cell cycle cytokinesis|positive regulation of contractile ring localization involved in cell cycle cytokinesis|upregulation of actomyosin contractile ring localization|up regulation of contractile ring localization involved in cell cycle cytokinesis						vw	2012-11-19T13:42:54Z						biological_process											owl:Class	
GO:0086096	biolink:NamedThing	adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	An adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart, where the activated adrenergic receptor transmits the signal by Gi-mediated inhibition of adenylate cyclase activity.	got7fsn_ti	G-inhibitory-coupled Beta2AR signaling pathway involved in heart process|Gi-coupled Beta2-AR signaling pathway involved in heart process|Gi-coupled adrenergic receptor signaling pathway involved in heart process|cardiac adrenergic receptor signaling pathway via inhibition of adenylate cyclase activity				Although Beta1-adrenergic receptors couple exclusively to the Gs protein, Beta2-adrenergic receptors couple to both Gs and Gi proteins. Coupling to Gi proteins may localize the Gs-mediated signaling.		bf							biological_process											owl:Class	
GO:2000249	biolink:NamedThing	regulation of actin cytoskeleton reorganization	Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.	got7fsn_ti	regulation of actin cytoskeleton remodeling|regulation of actin cytoskeleton reorganisation						vk	2010-11-11T01:25:26Z						biological_process											owl:Class	
GO:0044440	biolink:NamedThing	obsolete endosomal part	OBSOLETE. Any constituent part of an endosome, a membrane-bounded organelle to which materials ingested by endocytosis are delivered.	got7fsn_ti	endosomal subcomponent|endosome component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005768				True		NIF_Subcellular:sao1683772610		cellular_component											owl:Class	
GO:1904330	biolink:NamedThing	positive regulation of myofibroblast contraction	Any process that activates or increases the frequency, rate or extent of myofibroblast contraction.	got7fsn_ti	activation of MFB contraction|positive regulation of MF contraction|positive regulation of MFB contraction|up-regulation of MFB contraction|up regulation of MF contraction|up regulation of MFB contraction|up regulation of myofibroblast contraction|upregulation of MFB contraction|activation of MF contraction|up-regulation of myofibroblast contraction|up-regulation of MF contraction|upregulation of myofibroblast contraction|activation of myofibroblast contraction|upregulation of MF contraction						sl	2015-06-11T15:30:41Z						biological_process											owl:Class	
GO:0032768	biolink:NamedThing	regulation of monooxygenase activity	Any process that modulates the activity of a monooxygenase.	got7fsn_ti														biological_process											owl:Class	
GO:0042183	biolink:NamedThing	formate catabolic process	The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.	got7fsn_ti	formic acid catabolic process|formate catabolism|formic acid catabolism|formate degradation|formate breakdown													biological_process											owl:Class	
GO:1905028	biolink:NamedThing	negative regulation of membrane depolarization during AV node cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential.	got7fsn_ti	negative regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during AV node cell action potential|down regulation of membrane depolarization during AV node cell action potential|down regulation of membrane depolarization during AV node cardiac muscle cell action potential|downregulation of membrane depolarization during AV node cardiac muscle cell action potential|inhibition of membrane depolarization during AV node cell action potential|downregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|downregulation of membrane depolarization during AV node cell action potential|down regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|inhibition of membrane depolarization during atrioventricular node cardiac muscle cell action potential|inhibition of membrane depolarization during AV node cardiac muscle cell action potential|down-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|negative regulation of membrane depolarization during AV node cardiac muscle cell action potential|down-regulation of membrane depolarization during AV node cardiac muscle cell action potential						rph	2016-03-04T13:46:15Z						biological_process											owl:Class	
GO:0140348	biolink:NamedThing	lysophosphatidylcholine flippase activity	Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	lysophosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet)						pg	2019-05-16T13:45:17Z						molecular_function											owl:Class	
GO:1905148	biolink:NamedThing	negative regulation of smooth muscle hypertrophy	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy.	got7fsn_ti	inhibition of smooth muscle hypertrophy|down-regulation of smooth muscle hypertrophy|down regulation of smooth muscle hypertrophy|downregulation of smooth muscle hypertrophy						bc	2016-04-15T12:47:16Z						biological_process											owl:Class	
GO:0015479	biolink:NamedThing	obsolete outer membrane exporter porin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	outer membrane exporter porin				This term was made obsolete because it contains both component and function information.	GO:0009279|GO:0015288				True				molecular_function											owl:Class	
GO:1900236	biolink:NamedThing	positive regulation of Kit signaling pathway	Any process that activates or increases the frequency, rate or extent of Kit signaling pathway.	got7fsn_ti	upregulation of Kit signaling pathway|up regulation of stem cell factor receptor signaling pathway|activation of stem cell factor receptor signaling pathway|up regulation of stem cell factor signaling pathway|positive regulation of Kit signalling pathway|upregulation of stem cell factor receptor signaling pathway|activation of stem cell factor signaling pathway|up regulation of Kit signaling pathway|upregulation of stem cell factor signaling pathway|activation of Kit signaling pathway|up-regulation of Kit signaling pathway|up-regulation of stem cell factor receptor signaling pathway|positive regulation of stem cell factor signaling pathway|up-regulation of stem cell factor signaling pathway|positive regulation of stem cell factor receptor signaling pathway						bf	2012-03-23T02:54:32Z						biological_process											owl:Class	
GO:0018367	biolink:NamedThing	obsolete free L-amino acid racemization	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	free L-amino acid racemization				This term was made obsolete because it is not clear that this process occurs.	GO:0006520				True				biological_process											owl:Class	
GO:1901290	biolink:NamedThing	succinyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of succinyl-CoA.	got7fsn_ti	succinyl-CoA formation|succinyl-CoA biosynthesis|succinyl-CoA synthesis|succinyl-CoA anabolism						yaf	2012-08-17T16:13:57Z						biological_process											owl:Class	
GO:1900843	biolink:NamedThing	regulation of monodictyphenone biosynthetic process	Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process.	got7fsn_ti	regulation of monodictyphenone biosynthesis|regulation of monodictyphenone anabolism|regulation of monodictyphenone formation|regulation of monodictyphenone synthesis						di	2012-06-07T09:40:38Z						biological_process											owl:Class	
GO:0003296	biolink:NamedThing	apoptotic process involved in atrial ventricular junction remodeling	Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.	got7fsn_ti	apoptosis involved in atrio-ventricular junction remodeling|apoptosis involved in atrioventricular junction remodeling|apoptosis involved in atrial ventricular junction remodeling						dph	2009-10-22T08:43:11Z						biological_process											owl:Class	
GO:0060369	biolink:NamedThing	positive regulation of Fc receptor mediated stimulatory signaling pathway	Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.	got7fsn_ti	positive regulation of Fc receptor mediated stimulatory signalling pathway													biological_process											owl:Class	
GO:0060385	biolink:NamedThing	axonogenesis involved in innervation	The neurite development process that generates a long process of a neuron, as it invades a target tissue.	got7fsn_ti														biological_process											owl:Class	
GO:1902367	biolink:NamedThing	negative regulation of Notch signaling pathway involved in somitogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.	got7fsn_ti	inhibition of N signaling pathway involved in somitogenesis|down regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|inhibition of Notch signalling pathway involved in somitogenesis|downregulation of Notch signalling pathway involved in somitogenesis|negative regulation of N signalling pathway involved in somitogenesis|down-regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|inhibition of Notch receptor signalling pathway involved in formation of mesodermal clusters|inhibition of N signalling pathway involved in formation of mesodermal clusters|inhibition of Notch-receptor signaling pathway involved in somitogenesis|down-regulation of Notch-receptor signaling pathway involved in somitogenesis|down regulation of N signalling pathway involved in formation of mesodermal clusters|downregulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|inhibition of Notch signaling pathway involved in somitogenesis|down-regulation of Notch signaling pathway involved in somitogenesis|down regulation of Notch signaling pathway involved in somitogenesis|inhibition of Notch receptor signaling pathway involved in somitogenesis|inhibition of Notch-receptor signalling pathway involved in somitogenesis|down-regulation of N signaling pathway involved in somitogenesis|down regulation of Notch receptor signalling pathway involved in somitogenesis|down regulation of N signalling pathway involved in somitogenesis|down regulation of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch signaling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|inhibition of Notch receptor signalling pathway involved in somitogenesis|down-regulation of Notch receptor signalling pathway involved in somitogenesis|down regulation of N signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|downregulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|down regulation of N signaling pathway involved in somitogenesis|down-regulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|downregulation of Notch signaling pathway involved in formation of mesodermal clusters|negative regulation of N signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|downregulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|downregulation of Notch signalling pathway involved in formation of mesodermal clusters|negative regulation of N signalling pathway involved in formation of mesodermal clusters|inhibition of Notch receptor signaling pathway involved in formation of mesodermal clusters|down regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signaling pathway involved in somitogenesis|downregulation of Notch-receptor signalling pathway involved in somitogenesis|inhibition of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch signalling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signaling pathway involved in somitogenesis|downregulation of Notch receptor signaling pathway involved in somitogenesis|inhibition of N signalling pathway involved in somitogenesis|down regulation of Notch signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|down regulation of Notch signalling pathway involved in somitogenesis|downregulation of Notch receptor signalling pathway involved in somitogenesis|downregulation of N signalling pathway involved in formation of mesodermal clusters|down regulation of Notch receptor signaling pathway involved in somitogenesis|down-regulation of Notch receptor signaling pathway involved in somitogenesis|down-regulation of Notch-receptor signalling pathway involved in somitogenesis|downregulation of N signaling pathway involved in somitogenesis|inhibition of N signaling pathway involved in formation of mesodermal clusters|inhibition of Notch-receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signaling pathway involved in somitogenesis|down-regulation of N signalling pathway involved in somitogenesis|negative regulation of N signaling pathway involved in somitogenesis|downregulation of N signalling pathway involved in somitogenesis|inhibition of Notch signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of N signaling pathway involved in formation of mesodermal clusters|downregulation of N signaling pathway involved in formation of mesodermal clusters|downregulation of Notch signaling pathway involved in somitogenesis|down-regulation of N signalling pathway involved in formation of mesodermal clusters|inhibition of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signalling pathway involved in somitogenesis|negative regulation of Notch-receptor signalling pathway involved in somitogenesis|downregulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signalling pathway involved in somitogenesis|negative regulation of Notch signaling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch signalling pathway involved in formation of mesodermal clusters|downregulation of Notch-receptor signaling pathway involved in somitogenesis						dph	2013-08-20T18:27:20Z						biological_process											owl:Class	
GO:0033124	biolink:NamedThing	obsolete regulation of GTP catabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.	got7fsn_ti	regulation of GTP degradation|regulation of GTP catabolism|regulation of GTP breakdown				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0043087				True				biological_process											owl:Class	
GO:0008769	biolink:NamedThing	obsolete X-His dipeptidase activity	OBSOLETE. Catalysis of the hydrolysis of Xaa-His dipeptides.	got7fsn_ti	dipeptidase M|carnosinase activity|aminoacylhistidine dipeptidase activity|X-His dipeptidase activity|aminoacyl-histidine dipeptidase activity|homocarnosinase activity|Xaa-His dipeptidase activity				This term was made obsolete because it represents a gene product.	GO:0016805|GO:0008235				True		EC:3.4.13.3|MetaCyc:3.4.13.3-RXN		molecular_function											owl:Class	
GO:1903356	biolink:NamedThing	positive regulation of distal tip cell migration	Any process that activates or increases the frequency, rate or extent of distal tip cell migration.	got7fsn_ti	activation of distal tip cell migration|up regulation of distal tip cell migration|upregulation of distal tip cell migration|up-regulation of distal tip cell migration						pr	2014-08-21T10:05:26Z						biological_process											owl:Class	
GO:0034192	biolink:NamedThing	D-galactonate metabolic process	The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid.	got7fsn_ti	D-galactonate metabolism													biological_process											owl:Class	
GO:0035438	biolink:NamedThing	cyclic-di-GMP binding	Binding to cyclic-di-GMP, cyclic dimeric guanosine monophosphate.	got7fsn_ti	cyclic dinucleotide di-GMP binding|c-di-GMP binding|3',5'-cyclic di-GMP binding						bf	2010-04-09T02:40:17Z						molecular_function											owl:Class	
GO:0072735	biolink:NamedThing	response to tert-butyl hydroperoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.	got7fsn_ti	response to 2-methyl-prop-2-yl-hydroperoxide|response to t-BOOH						mah	2012-07-17T10:33:00Z						biological_process											owl:Class	
GO:1902709	biolink:NamedThing	cellular response to plumbagin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.	got7fsn_ti							mah	2014-02-20T13:50:04Z						biological_process											owl:Class	
GO:0060565	biolink:NamedThing	obsolete inhibition of APC-Cdc20 complex activity	OBSOLETE. Any process that prevents the activation of APC-Cdc20 complex activity regulating the mitotic cell cycle.	got7fsn_ti	inhibition of APC-Cdc20 complex activity|inhibition of APC/C activity during mitotic cell cycle|inhibition of mitotic anaphase-promoting complex activity|inhibition of cyclosome activity during mitotic cell cycle|inhibition of APC activity during mitotic cell cycle				This term was made obsolete because it was not clearly defined and thus used incorrectly in annotation.	GO:1990948	dph	2009-04-29T02:29:31Z		True				biological_process											owl:Class	
GO:1903455	biolink:NamedThing	negative regulation of androst-4-ene-3,17-dione biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.	got7fsn_ti	downregulation of androst-4-ene-3,17-dione synthesis|inhibition of androst-4-ene-3,17-dione biosynthesis|down regulation of androst-4-ene-3,17-dione synthesis|downregulation of androstenedione biosynthetic process|down-regulation of androst-4-ene-3,17-dione biosynthetic process|downregulation of androst-4-ene-3,17-dione anabolism|negative regulation of androst-4-ene-3,17-dione synthesis|down regulation of androstenedione biosynthetic process|down regulation of androst-4-ene-3,17-dione formation|negative regulation of androst-4-ene-3,17-dione biosynthesis|inhibition of androst-4-ene-3,17-dione anabolism|down-regulation of androst-4-ene-3,17-dione biosynthesis|inhibition of androstenedione|down-regulation of androstenedione biosynthetic process|negative regulation of androst-4-ene-3,17-dione anabolism|down regulation of androst-4-ene-3,17-dione biosynthetic process|inhibition of androst-4-ene-3,17-dione biosynthetic process|down regulation of androst-4-ene-3,17-dione biosynthesis|inhibition of androst-4-ene-3,17-dione formation|negative regulation of androstenedione biosynthetic process|down-regulation of androst-4-ene-3,17-dione synthesis|downregulation of androst-4-ene-3,17-dione formation|down-regulation of androst-4-ene-3,17-dione formation|downregulation of androst-4-ene-3,17-dione biosynthetic process|downregulation of androst-4-ene-3,17-dione biosynthesis|negative regulation of androst-4-ene-3,17-dione formation|down-regulation of androst-4-ene-3,17-dione anabolism|inhibition of androst-4-ene-3,17-dione synthesis|down regulation of androst-4-ene-3,17-dione anabolism						mr	2014-09-22T14:36:59Z						biological_process											owl:Class	
GO:1905220	biolink:NamedThing	negative regulation of platelet formation	Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation.	got7fsn_ti	down-regulation of platelet formation|downregulation of platelet extrusion|down regulation of platelet formation|down regulation of platelet extrusion|down-regulation of platelet extrusion|inhibition of platelet extrusion|downregulation of platelet formation|negative regulation of platelet extrusion|inhibition of platelet formation						sl	2016-06-06T22:15:54Z						biological_process											owl:Class	
GO:0010595	biolink:NamedThing	positive regulation of endothelial cell migration	Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.	got7fsn_ti														biological_process											owl:Class	
GO:1901468	biolink:NamedThing	positive regulation of ferulate catabolic process	Any process that activates or increases the frequency, rate or extent of ferulate catabolic process.	got7fsn_ti	up-regulation of ferulate catabolism|positive regulation of ferulate degradation|up regulation of ferulate degradation|positive regulation of ferulate breakdown|upregulation of ferulate catabolism|activation of ferulate catabolic process|upregulation of ferulate breakdown|activation of ferulate catabolism|up-regulation of ferulate catabolic process|upregulation of ferulate degradation|up-regulation of ferulate degradation|positive regulation of ferulate catabolism|upregulation of ferulate catabolic process|up regulation of ferulate breakdown|up regulation of ferulate catabolism|activation of ferulate breakdown|up regulation of ferulate catabolic process|activation of ferulate degradation|up-regulation of ferulate breakdown						tt	2012-10-02T14:38:56Z						biological_process											owl:Class	
GO:1904712	biolink:NamedThing	positive regulation of Wnt-Frizzled-LRP5/6 complex assembly	Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.	got7fsn_ti	up-regulation of Frizzled-LRP5/6 complex formation|positive regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|up-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|up regulation of WNT-FZD-LRP5 complex assembly|up regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|up regulation of WNT-FZD-LRP5 complex formation|activation of Frizzled-LRP5/6 complex formation|up regulation of Frizzled-LRP5/6 complex assembly|positive regulation of Frizzled-LRP5/6 complex assembly|up regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|upregulation of Frizzled-LRP5/6 complex assembly|positive regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|up regulation of WNT-FZD-LRP6 complex assembly|positive regulation of Wnt-induced Frizzled-LRP5/6 complex formation|activation of WNT-FZD-LRP5 complex assembly|activation of Frizzled-LRP5/6 complex assembly|up regulation of Frizzled-LRP5/6 complex formation|up-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|upregulation of Wnt-FZD-LRP5/6 trimeric complex assembly|activation of Wnt-induced Frizzled-LRP5/6 complex formation|positive regulation of Frizzled-LRP5/6 complex formation|activation of Wnt-FZD-LRP5/6 trimeric complex assembly|upregulation of WNT-FZD-LRP5 complex formation|upregulation of Wnt-induced Frizzled-LRP5/6 complex assembly|upregulation of WNT-FZD-LRP6 complex assembly|up-regulation of WNT-FZD-LRP6 complex formation|up regulation of Wnt-induced Frizzled-LRP5/6 complex formation|up regulation of WNT-FZD-LRP6 complex formation|up regulation of Wnt-FZD-LRP5/6 trimeric complex formation|positive regulation of WNT-FZD-LRP6 complex formation|up-regulation of Wnt-FZD-LRP5/6 trimeric complex formation|activation of Wnt-FZD-LRP5/6 trimeric complex formation|up-regulation of Frizzled-LRP5/6 complex assembly|upregulation of Frizzled-LRP5/6 complex formation|activation of WNT-FZD-LRP5 complex formation|upregulation of Wnt-FZD-LRP5/6 trimeric complex formation|upregulation of WNT-FZD-LRP6 complex formation|positive regulation of WNT-FZD-LRP5 complex formation|upregulation of WNT-FZD-LRP5 complex assembly|up-regulation of Wnt-induced Frizzled-LRP5/6 complex formation|up-regulation of WNT-FZD-LRP5 complex assembly|up-regulation of WNT-FZD-LRP5 complex formation|activation of Wnt-induced Frizzled-LRP5/6 complex assembly|up-regulation of WNT-FZD-LRP6 complex assembly|activation of WNT-FZD-LRP6 complex formation|activation of WNT-FZD-LRP6 complex assembly|upregulation of Wnt-induced Frizzled-LRP5/6 complex formation|positive regulation of Wnt-FZD-LRP5/6 trimeric complex formation|positive regulation of WNT-FZD-LRP6 complex assembly|positive regulation of WNT-FZD-LRP5 complex assembly						bf	2015-10-05T14:02:35Z						biological_process											owl:Class	
GO:0120041	biolink:NamedThing	positive regulation of macrophage proliferation	Any process that activates or increases the frequency, rate or extent of macrophage proliferation.	got7fsn_ti							krc	2017-05-10T20:45:01Z						biological_process											owl:Class	
GO:1903147	biolink:NamedThing	negative regulation of autophagy of mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy.	got7fsn_ti	down-regulation of mitophagy|inhibition of mitophagy|down regulation of mitochondrial degradation|down regulation of mitochondrion degradation|downregulation of mitochondrion degradation|down-regulation of mitochondrion degradation|inhibition of mitochondrion degradation						bf	2014-07-09T08:23:58Z						biological_process											owl:Class	
GO:0072738	biolink:NamedThing	cellular response to diamide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	got7fsn_ti	cellular response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide						mah	2012-07-17T10:33:00Z						biological_process											owl:Class	
GO:0098557	biolink:NamedThing	cytoplasmic side of smooth endoplasmic reticulum membrane	The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the cytoplasm.	got7fsn_ti							dos	2013-12-03T12:17:58Z						cellular_component											owl:Class	
GO:0075074	biolink:NamedThing	obsolete spore autophagy involved in appressorium formation on or near host	OBSOLETE. The process in which a symbiont spore digests parts of its own cytoplasm, occurring when the appressorium forms on or near the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	autophagy of spores during appressorium formation on or near host|spore autophagy during appressorium formation on or near host				The reason for obsoletion is that this term did not represent any specific host/symbiont process.					True				biological_process											owl:Class	
GO:1900045	biolink:NamedThing	negative regulation of protein K63-linked ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination.	got7fsn_ti	inhibition of protein K63-linked ubiquitination|inhibition of protein K63-linked polyubiquitination|negative regulation of protein K63-linked polyubiquitination|downregulation of protein K63-linked polyubiquitination|down regulation of protein K63-linked polyubiquitination|down-regulation of protein K63-linked polyubiquitination|down regulation of protein K63-linked ubiquitination|downregulation of protein K63-linked ubiquitination|down-regulation of protein K63-linked ubiquitination						bf	2012-01-19T11:44:41Z						biological_process											owl:Class	
GO:1904787	biolink:NamedThing	positive regulation of asymmetric protein localization involved in cell fate determination	Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.	got7fsn_ti	up regulation of asymmetric protein localization involved in cell fate commitment|positive regulation of cell fate commitment, asymmetric protein localization|activation of asymmetric protein localization resulting in cell fate commitment|up-regulation of asymmetric protein localisation involved in cell fate determination|up regulation of asymmetric protein localization resulting in cell fate commitment|activation of asymmetric protein localization involved in cell fate determination|positive regulation of asymmetric protein localization involved in cell fate commitment|upregulation of asymmetric protein localization resulting in cell fate commitment|up-regulation of cell fate commitment, asymmetric protein localization|upregulation of asymmetric protein localisation involved in cell fate determination|up-regulation of asymmetric protein localization involved in cell fate commitment|positive regulation of asymmetric protein localization resulting in cell fate commitment|upregulation of asymmetric protein localization involved in cell fate commitment|up regulation of asymmetric protein localisation involved in cell fate determination|up-regulation of asymmetric protein localization involved in cell fate determination|positive regulation of asymmetric protein localisation involved in cell fate determination|up-regulation of asymmetric protein localization resulting in cell fate commitment|up regulation of cell fate commitment, asymmetric protein localization|up regulation of asymmetric protein localization involved in cell fate determination|activation of cell fate commitment, asymmetric protein localization|activation of asymmetric protein localization involved in cell fate commitment|upregulation of cell fate commitment, asymmetric protein localization|upregulation of asymmetric protein localization involved in cell fate determination|activation of asymmetric protein localisation involved in cell fate determination				wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP)		es	2015-11-03T12:11:19Z						biological_process											owl:Class	
GO:1904683	biolink:NamedThing	regulation of metalloendopeptidase activity	Any process that modulates the frequency, rate or extent of metalloendopeptidase activity.	got7fsn_ti	regulation of metalloendoprotease activity|regulation of metalloendoproteinase activity						rph	2015-09-24T11:18:14Z						biological_process											owl:Class	
CHEBI:57894	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904411	biolink:NamedThing	positive regulation of secretory granule organization	Any process that activates or increases the frequency, rate or extent of secretory granule organization.	got7fsn_ti	activation of secretory granule organisation|up regulation of secretory granule organization|up regulation of secretory granule organization and biogenesis|up-regulation of secretory granule organization and biogenesis|positive regulation of secretory granule organisation|up regulation of secretory granule organisation|activation of secretory granule organization|activation of secretory granule organization and biogenesis|up-regulation of secretory granule organisation|upregulation of secretory granule organization|upregulation of secretory granule organization and biogenesis|up-regulation of secretory granule organization|positive regulation of secretory granule organization and biogenesis|upregulation of secretory granule organisation						sl	2015-06-25T19:40:55Z						biological_process											owl:Class	
GO:0018925	biolink:NamedThing	m-cresol metabolic process	The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes.	got7fsn_ti	m-cresol metabolism|meta-cresol metabolic process|3-hydroxytoluene metabolic process|3-hydroxytoluene metabolism|meta-cresol metabolism											UM-BBD_pathwayID:mcr|MetaCyc:M-CRESOL-DEGRADATION-PWY		biological_process											owl:Class	
GO:0030019	biolink:NamedThing	obsolete tryptase activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa, but with more restricted specificity than trypsin.	got7fsn_ti	skin tryptase activity|mast cell neutral proteinase activity|pituitary tryptase activity|mast cell protease II activity|mast cell proteinase II|mast cell serine proteinase tryptase activity|lung tryptase activity|mast cell tryptase activity|rat mast cell protease II|tryptase M|tryptase activity|mast cell serine proteinase II			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0055114	biolink:NamedThing	obsolete oxidation-reduction process	OBSOLETE. A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.	got7fsn_ti	oxidation reduction|oxidoreductase process	https://github.com/geneontology/go-ontology/issues/20250			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1905157	biolink:NamedThing	positive regulation of photosynthesis	Any process that activates or increases the frequency, rate or extent of photosynthesis.	got7fsn_ti	up regulation of photosynthesis|activation of photosynthesis|upregulation of photosynthesis|up-regulation of photosynthesis						tb	2016-04-19T16:12:39Z						biological_process											owl:Class	
GO:1901031	biolink:NamedThing	regulation of response to reactive oxygen species	Any process that modulates the frequency, rate or extent of response to reactive oxygen species.	got7fsn_ti	regulation of response to reactive oxidative species|regulation of response to active oxygen species|regulation of response to AOS|regulation of response to ROS|regulation of response to ROI|regulation of response to reactive oxygen intermediate						kmv	2012-06-20T07:47:06Z						biological_process											owl:Class	
GO:0033610	biolink:NamedThing	oxalate biosynthetic process	The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate.	got7fsn_ti	ethanedioic acid biosynthetic process|oxalic acid biosynthetic process|oxalate formation|oxalate biosynthesis|oxalate anabolism|oxalate synthesis|ethanedioate biosynthetic process													biological_process											owl:Class	
GO:0010822	biolink:NamedThing	positive regulation of mitochondrion organization	Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.	got7fsn_ti	positive regulation of mitochondrion organisation													biological_process											owl:Class	
GO:0032214	biolink:NamedThing	negative regulation of telomere maintenance via semi-conservative replication	Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.	got7fsn_ti	downregulation of telomere maintenance via semi-conservative replication|down-regulation of telomere maintenance via semi-conservative replication|inhibition of telomere maintenance via semi-conservative replication|down regulation of telomere maintenance via semi-conservative replication													biological_process											owl:Class	
GO:1905668	biolink:NamedThing	positive regulation of protein localization to endosome	Any process that activates or increases the frequency, rate or extent of protein localization to endosome.	got7fsn_ti	upregulation of protein localization in endosome|activation of protein localisation in endosome|up-regulation of protein localization to endosome|up-regulation of protein localization in endosome|up regulation of protein localization in endosome|upregulation of protein localisation in endosome|positive regulation of protein localisation in endosome|activation of protein localization in endosome|up regulation of protein localization to endosome|upregulation of protein localization to endosome|up regulation of protein localisation in endosome|up-regulation of protein localisation in endosome|positive regulation of protein localization in endosome|activation of protein localization to endosome						bc	2016-11-11T11:19:17Z						biological_process											owl:Class	
GO:1903573	biolink:NamedThing	negative regulation of response to endoplasmic reticulum stress	Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.	got7fsn_ti	down-regulation of cellular response to endoplasmic reticulum stress|downregulation of cellular response to endoplasmic reticulum stress|negative regulation of cellular response to endoplasmic reticulum stress|down-regulation of ER stress response|down-regulation of response to ER stress|inhibition of ER stress response|down regulation of cellular response to endoplasmic reticulum stress|down regulation of ER stress response|downregulation of response to ER stress|downregulation of ER stress response|negative regulation of response to ER stress|down-regulation of response to endoplasmic reticulum stress|inhibition of response to ER stress|down regulation of response to endoplasmic reticulum stress|negative regulation of ER stress response|inhibition of response to endoplasmic reticulum stress|down regulation of response to ER stress|downregulation of response to endoplasmic reticulum stress|inhibition of cellular response to endoplasmic reticulum stress						bf	2014-10-27T16:15:30Z						biological_process											owl:Class	
GO:0010887	biolink:NamedThing	negative regulation of cholesterol storage	Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti	negative regulation of cholesterol sequestration													biological_process											owl:Class	
GO:0034225	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation	OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter in response to zinc ion limitation|regulation of transcription from RNA polymerase II promoter in response to zinc deficiency				This term was obsoleted because it represents a GO-CAM model.	GO:0034224|GO:0006357				True				biological_process											owl:Class	
GO:0051571	biolink:NamedThing	positive regulation of histone H3-K4 methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.	got7fsn_ti	up regulation of histone H3-K4 methylation|upregulation of histone H3-K4 methylation|up-regulation of histone H3-K4 methylation|stimulation of histone H3-K4 methylation|activation of histone H3-K4 methylation													biological_process											owl:Class	
GO:1903815	biolink:NamedThing	negative regulation of collecting lymphatic vessel constriction	Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction.	got7fsn_ti	inhibition of collecting lymphatic vessel constriction|downregulation of lymphatic vessel myogenic constriction|inhibition of lymphatic vessel myogenic constriction|negative regulation of lymphatic vessel myogenic constriction|down-regulation of lymphatic vessel myogenic constriction|down regulation of collecting lymphatic vessel constriction|down-regulation of collecting lymphatic vessel constriction|downregulation of collecting lymphatic vessel constriction|down regulation of lymphatic vessel myogenic constriction						sl	2015-01-16T17:01:58Z						biological_process											owl:Class	
GO:1905251	biolink:NamedThing	epidermal growth factor receptor signaling pathway involved in heart process	Any epidermal growth factor receptor signaling pathway that is involved in heart process.	got7fsn_ti	epidermal growth factor receptor signalling pathway involved in heart process|EGF receptor signaling pathway involved in heart process|epidermal growth factor receptor signaling pathway involved in cardiac process|receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|EGF receptor signaling pathway involved in cardiac process|EGFR signaling pathway involved in cardiac process|EGF receptor signalling pathway involved in cardiac process|epidermal growth factor receptor signalling pathway involved in cardiac process|EGF receptor signalling pathway involved in heart process|EGFR signaling pathway involved in heart process|receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|ERBB1 signaling pathway involved in heart process|ERBB1 signaling pathway involved in cardiac process						bc	2016-06-10T09:20:54Z						biological_process											owl:Class	
GO:0006218	biolink:NamedThing	uridine catabolic process	The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.	got7fsn_ti	uridine breakdown|uridine catabolism|uridine degradation													biological_process											owl:Class	
GO:0004237	biolink:NamedThing	obsolete membrane dipeptidase activity	OBSOLETE. Catalysis of the hydrolysis of dipeptides.	got7fsn_ti	nonspecific dipeptidase activity|MDP|dehydropeptidase I (DPH I)|membrane dipeptidase activity|renal dipeptidase activity|microsomal dipeptidase activity|dipeptidyl hydrolase activity|dipeptide hydrolase|glycosyl-phosphatidylinositol-anchored renal dipeptidase activity|dehydropeptidase I activity|DPH I activity|aminodipeptidase activity				This term was made obsolete because it represents a gene product.	GO:0008235|GO:0016805				True		EC:3.4.13.19|MetaCyc:3.4.13.19-RXN		molecular_function											owl:Class	
GO:0070022	biolink:NamedThing	obsolete transforming growth factor beta receptor complex	OBSOLETE. A homodimeric receptor complex that consists of two TGF-beta receptor monomers.	got7fsn_ti	TGF-beta receptor complex|transforming growth factor beta receptor complex	https://github.com/geneontology/go-ontology/issues/12676			This term was made obsolete because it does not represent a physiological complex.					True				cellular_component											owl:Class	
GO:2000677	biolink:NamedThing	regulation of transcription regulatory region DNA binding	Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.	got7fsn_ti							yaf	2011-05-09T03:28:11Z						biological_process											owl:Class	
GO:1904310	biolink:NamedThing	cellular response to cordycepin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.	got7fsn_ti	cellular response to 3'-deoxyadenosine						sl	2015-06-10T17:10:35Z						biological_process											owl:Class	
GO:0009130	biolink:NamedThing	pyrimidine nucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside monophosphate anabolism|pyrimidine nucleoside monophosphate biosynthesis|pyrimidine nucleoside monophosphate formation|pyrimidine nucleoside monophosphate synthesis													biological_process											owl:Class	
GO:2000965	biolink:NamedThing	positive regulation of cellooligosaccharide catabolic process	Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process.	got7fsn_ti	positive regulation of cellooligosaccharide catabolism						tt	2011-08-01T02:28:47Z						biological_process											owl:Class	
GO:0043376	biolink:NamedThing	regulation of CD8-positive, alpha-beta T cell differentiation	Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.	got7fsn_ti	regulation of CD8-positive, alpha beta T-cell differentiation|regulation of CD8-positive T lymphocyte differentiation|regulation of CD8-positive T-lymphocyte differentiation|regulation of CD8-positive, alpha beta T lymphocyte differentiation|regulation of CD8-positive, alpha-beta T cell development|regulation of CD8-positive, alpha beta T-lymphocyte differentiation|regulation of CD8-positive T-cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0044329	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of cell to cell adhesion.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt-activated signaling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt receptor signalling pathway involved in positive regulation of cell-cell adhesion						jl	2010-08-18T04:16:50Z						biological_process											owl:Class	
GO:1903249	biolink:NamedThing	negative regulation of citrulline biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process.	got7fsn_ti	downregulation of citrulline anabolism|down-regulation of citrulline biosynthesis|negative regulation of citrulline synthesis|down-regulation of citrulline anabolism|down-regulation of citrulline synthesis|downregulation of citrulline biosynthetic process|down-regulation of citrulline formation|inhibition of citrulline synthesis|negative regulation of citrulline formation|inhibition of citrulline anabolism|inhibition of citrulline formation|down regulation of citrulline anabolism|down regulation of citrulline formation|inhibition of citrulline biosynthesis|negative regulation of citrulline biosynthesis|downregulation of citrulline formation|down-regulation of citrulline biosynthetic process|inhibition of citrulline biosynthetic process|down regulation of citrulline synthesis|down regulation of citrulline biosynthesis|downregulation of citrulline synthesis|down regulation of citrulline biosynthetic process|negative regulation of citrulline anabolism|downregulation of citrulline biosynthesis						rl	2014-08-04T15:24:46Z						biological_process											owl:Class	
GO:1904530	biolink:NamedThing	negative regulation of actin filament binding	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding.	got7fsn_ti	negative regulation of F-actin binding|down-regulation of actin filament binding|down regulation of actin cross-linking activity|down-regulation of actin cross-linking activity|downregulation of actin cross-linking activity|down regulation of actin filament binding|negative regulation of actin cross-linking activity|down regulation of F-actin binding|downregulation of F-actin binding|down-regulation of F-actin binding|inhibition of actin cross-linking activity|inhibition of actin filament binding|downregulation of actin filament binding|inhibition of F-actin binding						als	2015-07-30T10:41:55Z						biological_process											owl:Class	
GO:1904185	biolink:NamedThing	equatorial microtubule organizing center assembly	The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center.	got7fsn_ti	equatorial microtubule organizing center formation|equatorial microtubule organising centre assembly|EMTOC assembly|EMTOC formation|equatorial microtubule organising centre formation						mah	2015-05-05T14:24:30Z						biological_process											owl:Class	
GO:0018443	biolink:NamedThing	obsolete enzyme active site formation via L-aspartic 4-phosphoric anhydride	OBSOLETE. The transient phosphorylation of peptidyl-aspartic acid to form L-aspartic 4-phosphoric anhydride.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:4357737.					True		RESID:AA0033		biological_process											owl:Class	
GO:0018962	biolink:NamedThing	3-phenylpropionate metabolic process	The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins.	got7fsn_ti	3-phenylpropionate metabolism|phenylpropanoate metabolic process|hydrocinnamic acid metabolic process|phenylpropanoate metabolism|hydrocinnamic acid metabolism											UM-BBD_pathwayID:ppa		biological_process											owl:Class	
GO:1901313	biolink:NamedThing	obsolete positive regulation of gene expression involved in extracellular matrix organization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of gene expression involved in extracellular matrix organization.	got7fsn_ti	up regulation of gene expression involved in extracellular matrix organization|upregulation of gene expression involved in extracellular matrix organization|activation of expression of extracellular matrix proteins|positive regulation of expression of extracellular matrix proteins|up regulation of expression of extracellular matrix proteins|activation of extracellular matrix protein production|upregulation of extracellular matrix protein production|activation of gene expression involved in extracellular matrix organization|positive regulation of extracellular matrix protein production|up-regulation of expression of extracellular matrix proteins|up regulation of extracellular matrix protein production|up-regulation of gene expression involved in extracellular matrix organization|up-regulation of extracellular matrix protein production|upregulation of expression of extracellular matrix proteins				This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization.	GO:0010628	vk	2012-08-22T09:18:42Z		True				biological_process											owl:Class	
GO:0018337	biolink:NamedThing	obsolete enzyme active site formation via L-2',4',5'-topaquinone	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	enzyme active site formation via L-2',4',5'-topaquinone				This term was made obsolete because this process does not occur: the modification occurs before it can be an active site.					True				biological_process											owl:Class	
GO:1904803	biolink:NamedThing	regulation of translation involved in cellular response to UV	Any regulation of translation that is involved in cellular response to UV.	got7fsn_ti	regulation of translation involved in cellular response to UV radiation stimulus|regulation of protein formation involved in cellular response to UV|regulation of protein anabolism involved in cellular response to UV|regulation of protein synthesis involved in cellular response to UV|regulation of translation involved in cellular response to ultraviolet radiation stimulus|regulation of protein biosynthesis involved in cellular response to UV|regulation of translation involved in cellular response to UV light stimulus|regulation of translation involved in cellular response to ultraviolet light stimulus						mah	2015-11-10T12:12:41Z						biological_process											owl:Class	
GO:0030402	biolink:NamedThing	obsolete matrilysin-2 activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	MMP-26|matrilysin-2 activity|matrix metalloproteinase 26			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0052475	biolink:NamedThing	obsolete negative regulation by organism of symbiont cell-mediated immune response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of symbiont cell-based immune response|negative regulation by organism of symbiont cell-mediated immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0002664	biolink:NamedThing	regulation of T cell tolerance induction	Any process that modulates the frequency, rate, or extent of T cell tolerance induction.	got7fsn_ti	regulation of T-cell tolerance induction|regulation of T lymphocyte tolerance induction|regulation of T-lymphocyte tolerance induction													biological_process											owl:Class	
GO:0044575	biolink:NamedThing	cellulosome assembly	The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall.	got7fsn_ti							jl	2012-04-19T03:42:36Z						biological_process											owl:Class	
GO:0106012	biolink:NamedThing	positive regulation of protein localization to medial cortex	Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex.	got7fsn_ti							hjd	2017-04-27T17:36:17Z						biological_process											owl:Class	
GO:0033634	biolink:NamedThing	positive regulation of cell-cell adhesion mediated by integrin	Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.	got7fsn_ti	positive regulation of cell-cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0006380	biolink:NamedThing	obsolete poly-A binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	poly-A binding				This term was made obsolete because it represents a molecular function and not a biological process.	GO:0008143				True				biological_process											owl:Class	
GO:1902157	biolink:NamedThing	regulation of response to G2 DNA damage checkpoint signaling	Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.	got7fsn_ti	regulation of response to signal involved in G2/M transition DNA damage checkpoint|regulation of G2/M transition DNA damage checkpoint effector process						jl	2013-05-21T15:45:06Z						biological_process											owl:Class	
GO:1905021	biolink:NamedThing	regulation of threonine-tRNA ligase activity	Any process that modulates the frequency, rate or extent of threonine-tRNA ligase activity.	got7fsn_ti	regulation of threonine-transfer ribonucleate synthetase activity|regulation of threonyl ribonucleic synthetase activity|regulation of threonine translase activity|regulation of TRS|regulation of threonyl-transfer ribonucleate synthetase activity|regulation of threonyl-tRNA synthetase activity|regulation of threonyl-transfer ribonucleic acid synthetase activity|regulation of threonyl-transfer RNA synthetase activity|regulation of L-threonine:tRNAThr ligase (AMP-forming)						sl	2016-03-03T19:12:23Z						biological_process											owl:Class	
GO:1904525	biolink:NamedThing	positive regulation of DNA amplification	Any process that activates or increases the frequency, rate or extent of DNA amplification.	got7fsn_ti	upregulation of DNA amplification|activation of DNA amplification|up regulation of DNA amplification|up-regulation of DNA amplification						mcc	2015-07-29T16:24:25Z						biological_process											owl:Class	
GO:0106182	biolink:NamedThing	obsolete translocase activity acting on amino acids and peptides.	OBSOLETE. Catalysis of the translocation of amino acids and peptides.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:52:34Z		True		EC:7.4.-.-		molecular_function											owl:Class	
GO:1900790	biolink:NamedThing	pseurotin A biosynthetic process	The chemical reactions and pathways resulting in the formation of pseurotin A.	got7fsn_ti	Pseurotin anabolism|Pseurotin biosynthesis|pseurotin A biosynthesis|Pseurotin synthesis|pseurotin A anabolism|Pseurotin formation|pseurotin A formation|Pseurotin biosynthetic process|pseurotin A synthesis						di	2012-06-04T09:37:49Z						biological_process											owl:Class	
GO:0010149	biolink:NamedThing	obsolete senescence	OBSOLETE. A preprogrammed process associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components. An example of this process is found in Arabidopsis thaliana, when older leaves or floral organs are shed.	got7fsn_ti	senescence				This term was made obsolete because its name is ambiguous and it is covered by the two more specific terms: 'organ senescence ; GO:0010260' and 'cell aging ; GO:0007569'.					True		Wikipedia:Senescence		biological_process											owl:Class	
GO:0004210	biolink:NamedThing	obsolete caspase-7 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	caspase-7 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1902037	biolink:NamedThing	negative regulation of hematopoietic stem cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.	got7fsn_ti	down regulation of hemopoietic stem cell differentiation|inhibition of hemopoietic stem cell differentiation|down-regulation of hematopoietic stem cell differentiation|down regulation of hematopoietic stem cell differentiation|down-regulation of hemopoietic stem cell differentiation|inhibition of haemopoietic stem cell differentiation|down-regulation of haematopoietic stem cell differentiation|negative regulation of haemopoietic stem cell differentiation|down regulation of haemopoietic stem cell differentiation|downregulation of haemopoietic stem cell differentiation|inhibition of haematopoietic stem cell differentiation|downregulation of haematopoietic stem cell differentiation|downregulation of hemopoietic stem cell differentiation|down-regulation of haemopoietic stem cell differentiation|negative regulation of hemopoietic stem cell differentiation|down regulation of haematopoietic stem cell differentiation|negative regulation of haematopoietic stem cell differentiation|inhibition of hematopoietic stem cell differentiation|downregulation of hematopoietic stem cell differentiation						ss	2013-04-02T05:19:14Z						biological_process											owl:Class	
GO:1900012	biolink:NamedThing	positive regulation of corticotropin-releasing hormone receptor activity	Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity.	got7fsn_ti	positive regulation of adrenocorticotropin-releasing hormone receptor activity|up regulation of corticotropin-releasing factor receptor activity|up regulation of adrenocorticotropin-releasing hormone receptor activity|positive regulation of CRH receptor activity|up regulation of corticotropin-releasing hormone receptor activity|positive regulation of corticotropin-releasing factor receptor activity|up regulation of CRF receptor activity|positive regulation of CRF receptor activity|up regulation of CRH receptor activity						pr	2012-01-10T02:27:30Z						biological_process											owl:Class	
GO:1901172	biolink:NamedThing	phytoene metabolic process	The chemical reactions and pathways involving phytoene.	got7fsn_ti	phytoene metabolism						yaf	2012-07-19T09:47:46Z						biological_process											owl:Class	
GO:1902852	biolink:NamedThing	regulation of nuclear migration during mitotic telophase	Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase.	got7fsn_ti							vw	2014-04-02T15:35:34Z						biological_process											owl:Class	
GO:1903901	biolink:NamedThing	negative regulation of viral life cycle	Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.	got7fsn_ti	inhibition of viral life cycle|down regulation of viral replication|inhibition of lytic viral life cycle|down regulation of viral infectious cycle|inhibition of viral assembly, maturation, egress, and release|downregulation of viral assembly, maturation, egress, and release|down-regulation of viral life cycle|negative regulation of viral assembly, maturation, egress, and release|downregulation of viral replication|negative regulation of lytic viral life cycle|inhibition of viral replication|down-regulation of viral assembly, maturation, egress, and release|downregulation of lytic viral life cycle|down-regulation of viral infectious cycle|negative regulation of viral replication|down-regulation of lytic viral life cycle|down regulation of lytic viral life cycle|downregulation of viral life cycle|downregulation of viral infectious cycle|down regulation of viral life cycle|down-regulation of viral replication|negative regulation of viral infectious cycle|inhibition of viral infectious cycle|down regulation of viral assembly, maturation, egress, and release						pga	2015-02-09T10:22:16Z						biological_process											owl:Class	
GO:2000864	biolink:NamedThing	regulation of estradiol secretion	Any process that modulates the frequency, rate or extent of estradiol secretion.	got7fsn_ti	regulation of oestradiol secretion						bf	2011-07-26T08:49:13Z						biological_process											owl:Class	
GO:1904677	biolink:NamedThing	positive regulation of somatic stem cell division	Any process that activates or increases the frequency, rate or extent of somatic stem cell division.	got7fsn_ti	activation of somatic stem cell division|up regulation of somatic stem cell renewal|up-regulation of somatic stem cell division|positive regulation of somatic stem cell renewal|upregulation of somatic stem cell division|upregulation of somatic stem cell renewal|up regulation of somatic stem cell division|up-regulation of somatic stem cell renewal|activation of somatic stem cell renewal						rph	2015-09-14T08:47:34Z						biological_process											owl:Class	
GO:0060144	biolink:NamedThing	obsolete host cellular process involved in virus induced gene silencing	OBSOLETE. A cellular process occurring in the host cell that contributes to the process of posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19958			The reason for obsoletion is there there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1904558	biolink:NamedThing	response to dextromethorphan	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.	got7fsn_ti							mr	2015-08-14T16:09:17Z						biological_process											owl:Class	
GO:1905113	biolink:NamedThing	obsolete positive regulation of centromere clustering at the mitotic nuclear envelope	OBSOLETE. Any process that activates or increases the frequency, rate or extent of centromere clustering at the nuclear envelope.	got7fsn_ti	up-regulation of kinetochore clustering at spindle pole body|positive regulation of rabl configuration|activation of centromere-SPB clustering|up-regulation of centromere-SPB clustering|upregulation of centromere clustering at the nuclear envelope|up-regulation of kinetochore clustering at the old mitotic spindle pole body|up-regulation of kinetochore localization at spindle pole body|up regulation of kinetochore localization at spindle pole body|up regulation of kinetochore clustering at spindle pole body|upregulation of kinetochore clustering at the old mitotic spindle pole body|upregulation of kinetochore localization at spindle pole body|up regulation of centromere clustering at the nuclear periphery|activation of centromere clustering at the nuclear periphery|up regulation of centromere clustering at the nuclear envelope|upregulation of kinetochore clustering at SPB|up-regulation of rabl configuration|up regulation of kinetochore clustering at the old mitotic spindle pole body|activation of centromere clustering at the nuclear envelope|upregulation of centromere-SPB clustering|up-regulation of kinetochore clustering at SPB|positive regulation of kinetochore clustering at the old mitotic spindle pole body|positive regulation of kinetochore localization at spindle pole body|up-regulation of centromere clustering at the nuclear envelope|upregulation of kinetochore clustering at spindle pole body|activation of kinetochore clustering at the old mitotic spindle pole body|positive regulation of centromere-SPB clustering|positive regulation of centromere clustering at the nuclear periphery|up regulation of kinetochore clustering at SPB|activation of kinetochore localization at spindle pole body|upregulation of rabl configuration|up regulation of rabl configuration|activation of rabl configuration|up-regulation of centromere clustering at the nuclear periphery|upregulation of centromere clustering at the nuclear periphery|up regulation of centromere-SPB clustering|activation of kinetochore clustering at SPB|positive regulation of kinetochore clustering at SPB|positive regulation of kinetochore clustering at spindle pole body|activation of kinetochore clustering at spindle pole body				This term was obsoleted because it represented a phenotype.		al	2016-04-06T16:25:49Z		True				biological_process											owl:Class	
GO:1903016	biolink:NamedThing	negative regulation of exo-alpha-sialidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity.	got7fsn_ti	down-regulation of exo-alpha-sialidase activity|down-regulation of acetylneuraminidase activity|down regulation of acetylneuraminidase activity|inhibition of sialidase activity|downregulation of neuraminidase activity|down-regulation of neuraminidase activity|negative regulation of alpha-neuraminidase activity|negative regulation of acetylneuraminyl hydrolase activity|inhibition of neuraminidase activity|down regulation of N-acylneuraminate glycohydrolase activity|negative regulation of N-acylneuraminate glycohydrolase activity|down-regulation of acetylneuraminyl hydrolase activity|negative regulation of acetylneuraminidase activity|downregulation of exo-alpha-sialidase activity|inhibition of exo-alpha-sialidase activity|downregulation of acetylneuraminidase activity|inhibition of N-acylneuraminate glycohydrolase activity|down regulation of sialidase activity|down-regulation of N-acylneuraminate glycohydrolase activity|negative regulation of sialidase activity|inhibition of acetylneuraminidase activity|downregulation of N-acylneuraminate glycohydrolase activity|down regulation of acetylneuraminyl hydrolase activity|inhibition of alpha-neuraminidase activity|down-regulation of alpha-neuraminidase activity|down-regulation of sialidase activity|downregulation of acetylneuraminyl hydrolase activity|negative regulation of neuraminidase activity|inhibition of acetylneuraminyl hydrolase activity|down regulation of exo-alpha-sialidase activity|down regulation of alpha-neuraminidase activity|downregulation of sialidase activity|down regulation of neuraminidase activity|downregulation of alpha-neuraminidase activity				human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA)		rl	2014-05-14T18:15:17Z						biological_process											owl:Class	
GO:1902800	biolink:NamedThing	positive regulation of phosphodiesterase I activity	Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity.	got7fsn_ti	up-regulation of 5'-NPDase activity|activation of nucleotide pyrophosphatase/phosphodiesterase I activity|up regulation of 5'-phosphodiesterase activity|upregulation of exonuclease I activity|positive regulation of 5'-PDE activity|up regulation of alkaline phosphodiesterase activity|positive regulation of 5'-nucleotide phosphodiesterase activity|up-regulation of PDE I activity|upregulation of nucleotide pyrophosphatase/phosphodiesterase I activity|upregulation of PDE I activity|up regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|activation of 5'-exonuclease activity|positive regulation of alkaline phosphodiesterase activity|activation of phosphodiesterase I activity|activation of alkaline phosphodiesterase activity|up regulation of oligonucleate 5'-nucleotidohydrolase activity|upregulation of orthophosphoric diester phosphohydrolase activity|upregulation of 5'-phosphodiesterase activity|activation of oligonucleate 5'-nucleotidohydrolase activity|upregulation of 5'-PDE activity|activation of 5'NPDE activity|upregulation of 5'-NPDase activity|upregulation of 5'NPDE activity|up regulation of 5'-exonuclease activity|activation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up-regulation of 5'-PDase activity|up regulation of 5'NPDE activity|up-regulation of 5'-phosphodiesterase activity|up regulation of exonuclease I activity|positive regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|up-regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|upregulation of 5'-exonuclease activity|up-regulation of orthophosphoric diester phosphohydrolase activity|up regulation of phosphodiesterase I activity|positive regulation of 5'-PDase activity|upregulation of alkaline phosphodiesterase activity|activation of 5'-nucleotide phosphodiesterase activity|up-regulation of 5'-nucleotide phosphodiesterase activity|up regulation of 5'-PDE activity|activation of 5'-NPDase activity|up regulation of 5'-NPDase activity|upregulation of phosphodiesterase I activity|activation of 5'-PDE activity|upregulation of 5'-nucleotide phosphodiesterase activity|up-regulation of alkaline phosphodiesterase activity|positive regulation of 5'NPDE activity|upregulation of 5'-PDase activity|up regulation of orthophosphoric diester phosphohydrolase activity|up regulation of 5'-PDase activity|positive regulation of PDE I activity|activation of 5'-PDase activity|upregulation of oligonucleate 5'-nucleotidohydrolase activity|up-regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|activation of PDE I activity|upregulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up-regulation of 5'NPDE activity|up regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|positive regulation of orthophosphoric diester phosphohydrolase activity|up-regulation of 5'-exonuclease activity|up regulation of PDE I activity|positive regulation of oligonucleate 5'-nucleotidohydrolase activity|positive regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up-regulation of exonuclease I activity|positive regulation of 5'-NPDase activity|activation of exonuclease I activity|activation of 5'-phosphodiesterase activity|up-regulation of 5'-PDE activity|positive regulation of exonuclease I activity|activation of orthophosphoric diester phosphohydrolase activity|positive regulation of 5'-phosphodiesterase activity|positive regulation of 5'-exonuclease activity|up-regulation of oligonucleate 5'-nucleotidohydrolase activity|up regulation of 5'-nucleotide phosphodiesterase activity|up-regulation of phosphodiesterase I activity						al	2014-03-25T08:55:54Z						biological_process											owl:Class	
GO:1900005	biolink:NamedThing	positive regulation of serine-type endopeptidase activity	Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity.	got7fsn_ti	up regulation of blood coagulation factor activity|positive regulation of blood coagulation factor activity|up regulation of serine-type endopeptidase activity						kmv	2012-01-09T10:03:29Z						biological_process											owl:Class	
GO:0023068	biolink:NamedThing	obsolete signal transmission via phloem	OBSOLETE. The process in which a signal is conveyed via the phloem.	got7fsn_ti	signal transmission via phloem				This term was made obsolete because the meaning of the term is ambiguous.	GO:0010233|GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1904927	biolink:NamedThing	cellular response to palmitoleic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.	got7fsn_ti							mr	2016-01-27T23:07:31Z						biological_process											owl:Class	
GO:0100025	biolink:NamedThing	obsolete negative regulation of cellular amino acid biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular amino acid biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0006162	biolink:NamedThing	obsolete purine/pyrimidine nucleoside diphosphate reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	purine/pyrimidine nucleoside diphosphate reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0004748				True				biological_process											owl:Class	
GO:0017039	biolink:NamedThing	obsolete dipeptidyl-peptidase III activity	OBSOLETE. Catalysis of the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity; also acts on dipeptidyl 2-naphthylamides.	got7fsn_ti	dipeptidyl aminopeptidase III activity|enkephalinase B activity|dipeptidyl arylamidase III activity|dipeptidyl-peptidase III activity|red cell angiotensinase activity|DPP III activity			GO:0008239	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1902815	biolink:NamedThing	N,N'-diacetylchitobiose import	The directed movement of N,N'-diacetylchitobiose into a cell or organelle.	got7fsn_ti							tb	2014-03-27T20:58:58Z						biological_process											owl:Class	
GO:1905106	biolink:NamedThing	obsolete response to Dizocilpine	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-04-04T20:26:52Z		True				biological_process											owl:Class	
GO:0150145	biolink:NamedThing	positive regulation of CD80 production	Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process.	got7fsn_ti	positive regulation of CD80 biosynthetic process						bc	2019-12-08T10:29:00Z						biological_process											owl:Class	
GO:0071811	biolink:NamedThing	positive regulation of fever generation by positive regulation of prostaglandin biosynthesis	Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	got7fsn_ti							mah	2010-09-03T05:10:05Z						biological_process											owl:Class	
GO:1900446	biolink:NamedThing	obsolete negative regulation of tRNA transcription from RNA polymerase III promoter	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of tRNA transcription from RNA polymerase III promoter.	got7fsn_ti	inhibition of tRNA transcription from RNA polymerase III promoter|down-regulation of tRNA transcription from Pol III promoter|inhibition of tRNA transcription from Pol III promoter|down regulation of tRNA transcription from RNA polymerase III promoter|downregulation of tRNA transcription from Pol III promoter|negative regulation of tRNA transcription from Pol III promoter|downregulation of tRNA transcription from RNA polymerase III promoter|down regulation of tRNA transcription from Pol III promoter|down-regulation of tRNA transcription from RNA polymerase III promoter				The reason for obsoletion is that there is no specific regulator for negatively regulating tRNA transcription which is separable from general negative regulation of transcription from RNA polymerase III.		sart	2012-04-26T05:28:34Z		True				biological_process											owl:Class	
GO:0099176	biolink:NamedThing	regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex.	got7fsn_ti	regulation of trans-synaptic complex mediated retrograde trans-synaptic signaling													biological_process											owl:Class	
GO:0042214	biolink:NamedThing	terpene metabolic process	The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.	got7fsn_ti	terpene metabolism													biological_process											owl:Class	
GO:1901111	biolink:NamedThing	actinorhodin catabolic process	The chemical reactions and pathways resulting in the breakdown of actinorhodin.	got7fsn_ti	actinorhodin degradation|actinorhodin breakdown|actinorhodin catabolism						yaf	2012-07-11T03:06:00Z						biological_process											owl:Class	
GO:0018331	biolink:NamedThing	obsolete enzyme active site formation via O-phospho-L-serine	OBSOLETE. The transient phosphorylation of peptidyl-serine to form O-phospho-L-serine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:8061611 and PMID:12923550.					True		RESID:AA0037		biological_process											owl:Class	
GO:0055129	biolink:NamedThing	L-proline biosynthetic process	The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.	got7fsn_ti	pyrrolidine-2-carboxylic acid biosynthetic process						jid	2009-10-22T01:59:56Z						biological_process											owl:Class	
GO:1901877	biolink:NamedThing	negative regulation of calcium ion binding	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.	got7fsn_ti	down regulation of calcium ion storage activity|inhibition of calcium ion storage activity|inhibition of calcium ion binding|down-regulation of calcium ion binding|down-regulation of calcium ion storage activity|downregulation of calcium ion storage activity|downregulation of calcium ion binding|down regulation of calcium ion binding|negative regulation of calcium ion storage activity						rl	2013-02-06T12:38:22Z						biological_process											owl:Class	
GO:1902280	biolink:NamedThing	regulation of RNA helicase activity	Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.	got7fsn_ti	regulation of ATP-dependent RNA helicase activity						rb	2013-07-03T18:05:19Z						biological_process											owl:Class	
GO:0052534	biolink:NamedThing	obsolete positive regulation by organism of induced systemic resistance in symbiont	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of induced systemic resistance in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0051531	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042070	biolink:NamedThing	maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification	Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster.	got7fsn_ti	maintenance of oocyte nucleus location involved in oocyte dorsoventral axis specification|maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis determination|maintenance of oocyte nucleus location involved in oocyte dorsal-ventral axis specification|oocyte axis determination, oocyte nucleus anchoring|oocyte axis determination, maintenance of oocyte nucleus localization|maintenance of oocyte nucleus localization during oocyte axis determination|maintenance of oocyte nucleus position during oocyte axis determination|oocyte axis determination, maintenance of oocyte nucleus position|oocyte nucleus anchoring during oocyte axis determination										GO:0048127			biological_process											owl:Class	
GO:1904650	biolink:NamedThing	negative regulation of fat cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process.	got7fsn_ti	downregulation of fat cell apoptosis|downregulation of fat cell apoptotic process|negative regulation of adipocyte apoptotic process|down-regulation of fat cell apoptosis|inhibition of adipose cell apoptotic process|down-regulation of adipose cell apoptotic process|down regulation of fat cell apoptosis|down regulation of adipose cell apoptosis|inhibition of fat cell apoptosis|down regulation of adipocyte apoptosis|inhibition of adipocyte apoptotic process|negative regulation of adipose cell apoptosis|negative regulation of adipose cell apoptotic process|downregulation of adipocyte apoptotic process|downregulation of adipose cell apoptosis|inhibition of adipocyte apoptosis|down-regulation of adipocyte apoptotic process|down regulation of fat cell apoptotic process|inhibition of adipose cell apoptosis|negative regulation of adipocyte apoptosis|down regulation of adipocyte apoptotic process|down-regulation of fat cell apoptotic process|down regulation of adipose cell apoptotic process|downregulation of adipose cell apoptotic process|down-regulation of adipocyte apoptosis|negative regulation of fat cell apoptosis|inhibition of fat cell apoptotic process|downregulation of adipocyte apoptosis|down-regulation of adipose cell apoptosis						sl	2015-08-31T20:59:34Z						biological_process											owl:Class	
UBERON:0001675	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046263	biolink:NamedThing	nitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.	got7fsn_ti	nitrotoluene catabolism|nitrotoluene degradation|nitrotoluene breakdown													biological_process											owl:Class	
GO:0090055	biolink:NamedThing	positive regulation of silent mating-type cassette heterochromatin assembly	Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.	got7fsn_ti	positive regulation of chromatin silencing at silent mating-type cassette	https://github.com/geneontology/go-ontology/issues/19112					tb	2009-08-07T10:54:36Z						biological_process											owl:Class	
GO:0008222	biolink:NamedThing	obsolete tumor antigen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	tumor antigen				This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True				molecular_function											owl:Class	
GO:0005817	biolink:NamedThing	obsolete centrosomal mitotic factor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	centrosomal mitotic factor				This term was made obsolete because it was not defined.					True				cellular_component											owl:Class	
GO:0033030	biolink:NamedThing	negative regulation of neutrophil apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.	got7fsn_ti	downregulation of neutrophil apoptosis|down regulation of neutrophil apoptosis|inhibition of neutrophil apoptosis|negative regulation of neutrophil apoptosis|down-regulation of neutrophil apoptosis													biological_process											owl:Class	
GO:1904561	biolink:NamedThing	cellular response to diphenidol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.	got7fsn_ti							mr	2015-08-14T16:09:37Z						biological_process											owl:Class	
GO:0007627	biolink:NamedThing	obsolete larval behavior (sensu Insecta)	OBSOLETE. Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics, as seen in insects.	got7fsn_ti	larval behavior (sensu Insecta)			GO:0030537	This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.					True				biological_process											owl:Class	
GO:1902279	biolink:NamedThing	positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway	A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion.	got7fsn_ti	CCK-stimulated pancreatic amylase release|CCK-mediated pancreatic amylase secretion|activation of pancreatic amylase secretion by cholecystokinin signaling pathway|cholecystokinin-mediated pancreatic amylase secretion|up-regulation of pancreatic amylase secretion by cholecystokinin signaling pathway|up regulation of pancreatic amylase secretion by cholecystokinin signaling pathway|CCK-induced amylase release in pancreatic cell|upregulation of pancreatic amylase secretion by cholecystokinin signaling pathway						bf	2013-07-03T16:02:40Z						biological_process											owl:Class	
GO:0099052	biolink:NamedThing	vesicle scission involved in clathrin-mediated endocytosis	The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane.	got7fsn_ti					Like other vesicle scission events this involves dynamin. At least some of the dynamin recruiting factors are distinct to scission of clathrin-coated vesicles (PMID:21779028).									biological_process											owl:Class	
GO:0035471	biolink:NamedThing	luteinizing hormone signaling pathway involved in ovarian follicle development	The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.	got7fsn_ti	luteinizing hormone signalling pathway involved in ovarian follicle development						bf	2010-04-22T04:43:20Z						biological_process											owl:Class	
GO:0033342	biolink:NamedThing	negative regulation of collagen binding	Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding.	got7fsn_ti	down-regulation of collagen binding|down regulation of collagen binding|inhibition of collagen binding|downregulation of collagen binding													biological_process											owl:Class	
GO:0032887	biolink:NamedThing	regulation of spindle elongation	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.	got7fsn_ti														biological_process											owl:Class	
GO:0051761	biolink:NamedThing	sesquiterpene metabolic process	The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.	got7fsn_ti	sesquiterpene metabolism													biological_process											owl:Class	
GO:1902399	biolink:NamedThing	obsolete detection of stimulus involved in G1 DNA damage checkpoint	OBSOLETE. Any detection of stimulus that is involved in G1 DNA damage checkpoint.	got7fsn_ti	perception of stimulus involved in G1/S DNA damage checkpoint|perception of stimulus involved in G1 DNA damage checkpoint|detection of stimulus involved in G1/S DNA damage checkpoint|stimulus sensing involved in G1 DNA damage checkpoint|stimulus detection involved in G1/S DNA damage checkpoint|stimulus sensing involved in G1/S DNA damage checkpoint|stimulus detection involved in G1 DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		jl	2013-09-12T12:01:49Z		True				biological_process											owl:Class	
GO:1905403	biolink:NamedThing	negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.	got7fsn_ti	down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|downregulation of activated CD8-positive, alpha-beta T-cell apoptosis|down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T cell apoptosis|inhibition of activated CD8-positive, alpha-beta T-cell apoptotic process|negative regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD8-positive, alpha-beta T cell apoptotic process|negative regulation of activated CD8-positive, alpha-beta T cell apoptosis|down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T cell apoptotic process|down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down regulation of activated CD8-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|inhibition of activated CD8-positive, alpha-beta T cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T cell apoptosis|down regulation of activated CD8-positive, alpha-beta T cell apoptosis|downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD8-positive, alpha-beta T-cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD8-positive, alpha-beta T-cell apoptosis|downregulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T cell apoptotic process|inhibition of activated CD8-positive, alpha-beta T cell apoptosis|down-regulation of activated CD8-positive, alpha-beta T-cell apoptosis|inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process						pga	2016-08-25T09:14:03Z						biological_process											owl:Class	
GO:2000513	biolink:NamedThing	positive regulation of granzyme A production	Any process that activates or increases the frequency, rate or extent of granzyme A production.	got7fsn_ti							ebc	2011-03-22T10:31:36Z						biological_process											owl:Class	
GO:1903214	biolink:NamedThing	regulation of protein targeting to mitochondrion	Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.	got7fsn_ti	regulation of protein import into mitochondrion|regulation of protein-mitochondrial targeting|regulation of protein targeting to mitochondria|regulation of mitochondrial protein import|regulation of mitochondrial translocation						bf	2014-07-24T10:17:13Z						biological_process											owl:Class	
GO:1904826	biolink:NamedThing	regulation of hydrogen sulfide biosynthetic process	Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process.	got7fsn_ti	regulation of hydrogen sulphide biosynthesis|regulation of hydrogen sulphide biosynthetic process|regulation of hydrogen sulfide anabolism|regulation of hydrogen sulfide biosynthesis|regulation of hydrogen sulfide formation|regulation of hydrogen sulfide synthesis						rph	2015-11-24T10:15:26Z						biological_process											owl:Class	
GO:0043445	biolink:NamedThing	acetone biosynthetic process	The chemical reactions and pathways resulting in the formation of acetone, propan-2-one.	got7fsn_ti	propan-2-one biosynthesis|2-propanone biosynthesis|propan-2-one biosynthetic process|acetone formation|acetone synthesis|acetone biosynthesis|2-propanone biosynthetic process|dimethyl ketone biosynthetic process|dimethyl ketone biosynthesis|acetone anabolism													biological_process											owl:Class	
UBERON:0003077	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150045	biolink:NamedThing	regulation of synaptic signaling by nitric oxide	Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide.	got7fsn_ti							bc	2018-04-23T09:42:25Z						biological_process											owl:Class	
GO:0099059	biolink:NamedThing	integral component of presynaptic active zone membrane	The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0070108	biolink:NamedThing	negative regulation of interleukin-27-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor.	got7fsn_ti	negative regulation of IL27RA/IL6ST signaling pathway|negative regulation of interleukin-27-mediated signalling pathway|negative regulation of IL-27-mediated signaling pathway													biological_process											owl:Class	
GO:0120180	biolink:NamedThing	cell-substrate junction disassembly	The disaggregation of a cell-substrate junction into its constituent components.	got7fsn_ti							krc	2018-07-12T17:33:35Z						biological_process											owl:Class	
GO:1901186	biolink:NamedThing	positive regulation of ERBB signaling pathway	Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway.	got7fsn_ti	up-regulation of ErbB signaling|activation of ERBB signaling pathway|activation of ErbB signaling|activation of EGFR family signaling pathway|up-regulation of EGF receptor family signaling pathway|up-regulation of ERBB signaling pathway|up regulation of ERBB signaling pathway|upregulation of EGFR family signaling pathway|up-regulation of EGFR family signaling pathway|up regulation of ERBB signalling pathway|positive regulation of ERBB signalling pathway|upregulation of ErbB signaling|activation of ERBB signalling pathway|up-regulation of ERBB signalling pathway|upregulation of ERBB signalling pathway|up regulation of EGFR family signaling pathway|upregulation of EGF receptor family signaling pathway|positive regulation of EGF receptor family signaling pathway|activation of EGF receptor family signaling pathway|upregulation of ERBB signaling pathway|up regulation of ErbB signaling|positive regulation of EGFR family signaling pathway|up regulation of EGF receptor family signaling pathway|positive regulation of ErbB signaling						rl	2012-07-24T07:37:43Z						biological_process											owl:Class	
GO:0060595	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in mammary gland specification	The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.	got7fsn_ti	fibroblast growth factor receptor signalling pathway involved in mammary gland specification						dph	2009-05-13T10:38:18Z						biological_process											owl:Class	
GO:1904750	biolink:NamedThing	negative regulation of protein localization to nucleolus	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.	got7fsn_ti	down-regulation of protein localization in nucleolus|downregulation of protein localization in nucleolus|down-regulation of protein localisation in nucleolus|inhibition of protein localisation in nucleolus|inhibition of protein localization in nucleolus|inhibition of protein localisation to nucleolus|downregulation of protein localisation to nucleolus|down-regulation of protein localization to nucleolus|inhibition of protein localization to nucleolus|down regulation of protein localization in nucleolus|down regulation of protein localization to nucleolus|down regulation of protein localisation in nucleolus|negative regulation of protein localization in nucleolus|negative regulation of protein localisation to nucleolus|down regulation of protein localisation to nucleolus|downregulation of protein localisation in nucleolus|negative regulation of protein localisation in nucleolus|down-regulation of protein localisation to nucleolus|downregulation of protein localization to nucleolus						nc	2015-10-19T15:16:24Z						biological_process											owl:Class	
GO:0008008	biolink:NamedThing	obsolete membrane attack complex protein beta2 chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	membrane attack complex protein beta2 chain			GO:0005579	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:0042201	biolink:NamedThing	N-cyclopropylmelamine metabolic process	The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide.	got7fsn_ti	cyromazine metabolism|N-cyclopropylmelamine metabolism|cyromazine metabolic process													biological_process											owl:Class	
GO:0100014	biolink:NamedThing	obsolete positive regulation of mating type switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates mating type switching.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:2000081	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.	got7fsn_ti	positive regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|positive regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation						tb	2010-08-27T11:23:00Z						biological_process											owl:Class	
GO:1901188	biolink:NamedThing	negative regulation of ephrin receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway.	got7fsn_ti	down-regulation of ephrin receptor signaling pathway|down regulation of ephrin receptor signaling pathway|negative regulation of Eph receptor signalling pathway|downregulation of Eph receptor signaling pathway|downregulation of ephrin receptor signaling pathway|negative regulation of Eph receptor signaling pathway|down-regulation of Eph receptor signaling pathway|inhibition of Eph receptor signaling pathway|inhibition of ephrin receptor signaling pathway|down regulation of Eph receptor signalling pathway|downregulation of Eph receptor signalling pathway|down-regulation of Eph receptor signalling pathway|down regulation of Eph receptor signaling pathway|inhibition of Eph receptor signalling pathway						rl	2012-07-24T07:42:14Z						biological_process											owl:Class	
GO:0035499	biolink:NamedThing	carnosine biosynthetic process	The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).	got7fsn_ti	carnosine biosynthesis|carnosine synthesis|carnosine formation|carnosine anabolism						bf	2010-04-29T01:20:56Z						biological_process											owl:Class	
GO:0031565	biolink:NamedThing	obsolete cytokinesis checkpoint	OBSOLETE. A mitotic cell cycle checkpoint that detects a defect in cytokinesis and negatively regulates G2/M transition.	got7fsn_ti	septin checkpoint|contractile ring checkpoint				The reason this term was made obsolete is that the two terms cytokinesis checkpoint (GO:0031565) and cytokinesis after mitosis (GO:0000078) were conflated in meaning.	GO:0044879|GO:0044878				True	GO:0000135			biological_process											owl:Class	
GO:2000700	biolink:NamedThing	positive regulation of cardiac muscle cell myoblast differentiation	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation.	got7fsn_ti	positive regulation of myocardial precursor cell differentiation|positive regulation of cardiac myoblast differentiation						yaf	2011-05-25T09:08:09Z						biological_process											owl:Class	
GO:1904274	biolink:NamedThing	tricellular tight junction assembly	The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.	got7fsn_ti	tricellular tight junction formation						mr	2015-05-29T16:31:00Z						biological_process											owl:Class	
GO:1905264	biolink:NamedThing	blasticidin S metabolic process	The chemical reactions and pathways involving blasticidin S.	got7fsn_ti	blasticidin S metabolism						pr	2016-06-14T12:47:05Z						biological_process											owl:Class	
CHEBI:62064	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905172	biolink:NamedThing	RISC complex binding	Binding to a RISC complex.	got7fsn_ti	RNA-induced silencing complex binding						bf	2016-05-02T19:27:02Z						molecular_function											owl:Class	
GO:0016186	biolink:NamedThing	obsolete synaptic vesicle fission	OBSOLETE. Separation of a synaptic vesicle from the presynaptic membrane.	got7fsn_ti	synaptic vesicle fission				This term was made obsolete because it was wrongly defined.	GO:0016192				True				biological_process											owl:Class	
GO:0006695	biolink:NamedThing	cholesterol biosynthetic process	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti	cholesterol biosynthesis|cholesterol formation|cholesterol synthesis|cholesterol anabolism													biological_process											owl:Class	
GO:0005991	biolink:NamedThing	trehalose metabolic process	The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	got7fsn_ti	mykose metabolism|mykose metabolic process|mycose metabolic process|trehalose metabolism|mycose metabolism													biological_process											owl:Class	
GO:1900153	biolink:NamedThing	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.	got7fsn_ti	activation of mRNA catabolic process, deadenylylation-dependent|positive regulation of mRNA breakdown, deadenylation-dependent decay|up regulation of mRNA breakdown, deadenylation-dependent decay|positive regulation of mRNA catabolic process, deadenylylation-dependent|up-regulation of mRNA degradation, deadenylation-dependent decay|activation of mRNA degradation, deadenylation-dependent decay|upregulation of mRNA catabolic process, deadenylation-dependent|up-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|upregulation of mRNA degradation, deadenylation-dependent decay|upregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|upregulation of mRNA breakdown, deadenylation-dependent decay|upregulation of mRNA catabolic process, deadenylylation-dependent|activation of deadenylation-dependent mRNA decay|up regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|up-regulation of mRNA breakdown, deadenylation-dependent decay|up-regulation of mRNA catabolism, deadenylation-dependent|positive regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|up-regulation of mRNA catabolic process, deadenylation-dependent|activation of mRNA breakdown, deadenylation-dependent decay|up regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|activation of mRNA catabolism, deadenylation-dependent|up regulation of mRNA degradation, deadenylation-dependent decay|up regulation of mRNA catabolism, deadenylylation-dependent|upregulation of mRNA catabolism, deadenylylation-dependent|activation of nuclear mRNA catabolic process, deadenylation-dependent decay|up-regulation of mRNA catabolism, deadenylylation-dependent|up regulation of mRNA catabolic process, deadenylylation-dependent|up-regulation of mRNA catabolic process, deadenylylation-dependent|up regulation of mRNA catabolism, deadenylation-dependent|positive regulation of mRNA catabolic process, deadenylation-dependent|upregulation of mRNA catabolism, deadenylation-dependent|positive regulation of deadenylation-dependent mRNA decay|activation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|up-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|upregulation of deadenylation-dependent mRNA decay|up regulation of deadenylation-dependent mRNA decay|positive regulation of mRNA catabolism, deadenylylation-dependent|up-regulation of deadenylation-dependent mRNA decay|upregulation of nuclear mRNA catabolic process, deadenylation-dependent decay|activation of mRNA catabolic process, deadenylation-dependent|positive regulation of mRNA degradation, deadenylation-dependent decay|positive regulation of mRNA catabolism, deadenylation-dependent|up regulation of mRNA catabolic process, deadenylation-dependent|activation of mRNA catabolism, deadenylylation-dependent						bf	2012-03-07T09:14:52Z						biological_process											owl:Class	
GO:0046042	biolink:NamedThing	ITP biosynthetic process	The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate.	got7fsn_ti	ITP biosynthesis|ITP synthesis|ITP anabolism|ITP formation													biological_process											owl:Class	
GO:2000800	biolink:NamedThing	regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.	got7fsn_ti	regulation of endocardial cushion to mesenchymal transition involved in valve formation						bf	2011-07-01T12:31:18Z						biological_process											owl:Class	
GO:1903421	biolink:NamedThing	regulation of synaptic vesicle recycling	Any process that modulates the frequency, rate or extent of synaptic vesicle recycling.	got7fsn_ti	regulation of kiss-and-run synaptic vesicle recycling|regulation of kiss-and-stay synaptic vesicle recycling				An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype		pad	2014-09-09T15:27:50Z						biological_process											owl:Class	
GO:1900699	biolink:NamedThing	negative regulation of o-orsellinic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process.	got7fsn_ti	downregulation of o-orsellinic acid biosynthetic process|inhibition of o-orsellinic acid synthesis|inhibition of o-orsellinic acid biosynthetic process|down regulation of o-orsellinic acid anabolism|negative regulation of o-orsellinic acid biosynthesis|inhibition of o-orsellinic acid anabolism|downregulation of o-orsellinic acid formation|down-regulation of o-orsellinic acid biosynthesis|negative regulation of o-orsellinic acid formation|down regulation of o-orsellinic acid synthesis|down regulation of o-orsellinic acid biosynthetic process|down-regulation of o-orsellinic acid anabolism|down regulation of o-orsellinic acid biosynthesis|downregulation of o-orsellinic acid synthesis|down-regulation of o-orsellinic acid biosynthetic process|downregulation of o-orsellinic acid anabolism|downregulation of o-orsellinic acid biosynthesis|inhibition of o-orsellinic acid formation|inhibition of o-orsellinic acid biosynthesis|negative regulation of o-orsellinic acid anabolism|down-regulation of o-orsellinic acid formation|down-regulation of o-orsellinic acid synthesis|down regulation of o-orsellinic acid formation|negative regulation of o-orsellinic acid synthesis						di	2012-05-22T04:57:08Z						biological_process											owl:Class	
GO:0003811	biolink:NamedThing	obsolete complement activity	OBSOLETE. Any of a set of activities involved in the complement cascade.	got7fsn_ti	complement activity				This term was made obsolete because it refers to involvement in a biological process.	GO:0006956				True				molecular_function											owl:Class	
GO:0140652	biolink:NamedThing	pyripyropene A biosynthetic process	The chemical reactions and pathways resulting in the formation of pyripyropene A.	got7fsn_ti	pyripyropene A formation|pyripyropene A biosynthesis|pyripyropene A anabolism|pyripyropene A synthesis	https://github.com/geneontology/go-ontology/issues/21496					pg	2021-05-27T08:33:29Z						biological_process											owl:Class	
GO:1904367	biolink:NamedThing	positive regulation of chemokinesis	Any process that activates or increases the frequency, rate or extent of chemokinesis.	got7fsn_ti	upregulation of chemokinesis|activation of chemokinesis|up-regulation of chemokinesis|up regulation of chemokinesis						sl	2015-06-15T22:44:18Z						biological_process											owl:Class	
GO:0072280	biolink:NamedThing	establishment of planar polarity involved in metanephric nephron morphogenesis	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros.	got7fsn_ti	establishment of planar cell polarity involved in metanephric nephron morphogenesis						mah	2010-04-01T03:17:18Z						biological_process											owl:Class	
GO:0004248	biolink:NamedThing	obsolete stromelysin 1 activity	OBSOLETE. Catalysis of the preferential cleavage where P1', P2' and P3' are hydrophobic residues.	got7fsn_ti	transin activity|procollagenase activator|MMP-3|stromelysin|neutral proteoglycanase activity|matrix metalloproteinase 3 activity|collagen-activating protein|proteoglycanase activity|collagenase activating protein|stromelysin 1 activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905946	biolink:NamedThing	negative regulation of response to calcium ion	Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion.	got7fsn_ti	inhibition of response to Ca2+ ion|down-regulation of response to calcium ion|negative regulation of response to Ca2+ ion|down regulation of response to Ca2+ ion|down-regulation of response to Ca2+ ion|downregulation of response to Ca2+ ion|inhibition of response to calcium ion|downregulation of response to calcium ion|down regulation of response to calcium ion						bc	2017-02-13T10:56:41Z						biological_process											owl:Class	
GO:1905608	biolink:NamedThing	positive regulation of presynapse assembly	Any process that activates or increases the frequency, rate or extent of presynapse assembly.	got7fsn_ti	positive regulation of presynaptic terminal assembly|positive regulation of presynapse biogenesis|up-regulation of presynapse biogenesis|activation of presynapse assembly|up regulation of presynapse assembly|up regulation of presynaptic terminal assembly|upregulation of presynapse biogenesis|activation of presynapse biogenesis|up-regulation of presynaptic terminal assembly|up-regulation of presynapse assembly|up regulation of presynapse biogenesis|activation of presynaptic terminal assembly|upregulation of presynapse assembly|upregulation of presynaptic terminal assembly						bc	2016-10-27T16:08:28Z						biological_process											owl:Class	
GO:1902109	biolink:NamedThing	negative regulation of mitochondrial membrane permeability involved in apoptotic process	Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process.	got7fsn_ti	negative regulation of mitochondrial membrane permeability involved in type I programmed cell death|mitochondrial membrane impermeability involved in apoptotic programmed cell death|mitochondrial membrane impermeabilization involved in apoptotic programmed cell death|negative regulation of transport across mitochondrial membrane involved in apoptosis|negative regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|mitochondrial membrane impermeability involved in apoptotic program|negative regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|mitochondrial membrane impermeabilization involved in apoptotic program|mitochondrial membrane impermeabilization involved in programmed cell death by apoptosis|negative regulation of transport across mitochondrial membrane involved in type I programmed cell death|negative regulation of mitochondrial membrane permeability involved in apoptotic cell death|mitochondrial membrane impermeability involved in apoptotic process|negative regulation of mitochondrial membrane permeability involved in apoptosis|negative regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|mitochondrial membrane impermeability involved in apoptotic cell death|mitochondrial membrane impermeability involved in signaling (initiator) caspase activity|mitochondrial membrane impermeabilization involved in apoptosis|mitochondrial membrane impermeabilization involved in apoptotic process|negative regulation of transport across mitochondrial membrane involved in apoptotic program|mitochondrial membrane impermeabilization involved in apoptotic cell death|negative regulation of mitochondrial membrane permeability involved in apoptotic program|negative regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|negative regulation of transport across mitochondrial membrane involved in apoptotic cell death|mitochondrial membrane impermeabilization involved in signaling (initiator) caspase activity|mitochondrial membrane impermeability involved in programmed cell death by apoptosis|negative regulation of transport across mitochondrial membrane involved in apoptotic process|mitochondrial membrane impermeability involved in type I programmed cell death|negative regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|mitochondrial membrane impermeabilization involved in type I programmed cell death|negative regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|mitochondrial membrane impermeability involved in apoptosis						pr	2013-05-03T12:11:53Z						biological_process											owl:Class	
GO:0050428	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.	got7fsn_ti	phosphoadenosine phosphosulfate biosynthetic process|3'-phosphoadenylyl-sulfate biosynthetic process|3'-phosphoadenosine 5'-phosphosulphate biosynthesis|PAPS biosynthetic process|PAPS biosynthesis|3'-phosphoadenosine 5'-phosphosulfate synthesis|3'-phosphoadenosine 5'-phosphosulfate formation|phosphoadenosine phosphosulfate biosynthesis|adenosine 3'-phosphate 5'-phosphosulfate biosynthesis|3'-phosphoadenylyl-sulfate biosynthesis|adenosine 3'-phosphate 5'-phosphosulfate biosynthetic process|3'-phosphoadenosine 5'-phosphosulfate anabolism|3'-phosphoadenosine 5'-phosphosulphate biosynthetic process|3'-phosphoadenosine 5'-phosphosulfate biosynthesis													biological_process											owl:Class	
GO:1904543	biolink:NamedThing	negative regulation of free ubiquitin chain polymerization	Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization.	got7fsn_ti	down-regulation of free ubiquitin chain polymerization|down regulation of free ubiquitin chain polymerization|inhibition of free ubiquitin chain polymerization|downregulation of free ubiquitin chain polymerization				An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype).		pad	2015-08-11T11:45:00Z						biological_process											owl:Class	
GO:0042544	biolink:NamedThing	melibiose biosynthetic process	The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.	got7fsn_ti	melibiose synthesis|melibiose anabolism|melibiose biosynthesis|melibiose formation													biological_process											owl:Class	
GO:0043736	biolink:NamedThing	obsolete DNA-3-methyladenine glycosylase IV activity	OBSOLETE. Catalysis of the hydrolysis of alkylated DNA; recognizes and removes both N-3- and N-7-methyl purines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.	got7fsn_ti	MpgII|DNA-3-methyladenine glycosylase IV activity|Mpg II				This term was made obsolete because it represents an enzyme with four different activities.	GO:0008725|GO:0043916|GO:0052822|GO:0052821				True				molecular_function											owl:Class	
GO:1903996	biolink:NamedThing	negative regulation of non-membrane spanning protein tyrosine kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.	got7fsn_ti	negative regulation of janus kinase 3 activity|down regulation of janus kinase 3 activity|down-regulation of cytoplasmic protein tyrosine kinase activity|downregulation of janus kinase 1 activity|downregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down regulation of non-specific protein-tyrosine kinase activity|down-regulation of non-specific protein-tyrosine kinase activity|inhibition of janus kinase 3 activity|negative regulation of focal adhesion kinase activity|downregulation of janus kinase 3 activity|downregulation of focal adhesion kinase activity|inhibition of non-specific protein-tyrosine kinase activity|downregulation of non-specific protein-tyrosine kinase activity|down regulation of cytoplasmic protein tyrosine kinase activity|downregulation of janus kinase 2 activity|inhibition of focal adhesion kinase activity|down regulation of janus kinase 1 activity|downregulation of non-membrane spanning protein tyrosine kinase activity|inhibition of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|negative regulation of p60c-src protein tyrosine kinase activity|down-regulation of janus kinase 1 activity|inhibition of janus kinase 1 activity|down regulation of p60c-src protein tyrosine kinase activity|downregulation of cytoplasmic protein tyrosine kinase activity|inhibition of non-membrane spanning protein tyrosine kinase activity|downregulation of Bruton's tyrosine kinase activity|inhibition of Bruton's tyrosine kinase activity|down-regulation of janus kinase 3 activity|down-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|negative regulation of non-specific protein-tyrosine kinase activity|negative regulation of janus kinase 1 activity|down-regulation of focal adhesion kinase activity|down-regulation of Bruton's tyrosine kinase activity|down regulation of focal adhesion kinase activity|downregulation of p60c-src protein tyrosine kinase activity|down regulation of non-membrane spanning protein tyrosine kinase activity|negative regulation of janus kinase 2 activity|inhibition of janus kinase 2 activity|down-regulation of p60c-src protein tyrosine kinase activity|inhibition of p60c-src protein tyrosine kinase activity|negative regulation of Bruton's tyrosine kinase activity|down-regulation of non-membrane spanning protein tyrosine kinase activity|down-regulation of janus kinase 2 activity|down regulation of janus kinase 2 activity|inhibition of cytoplasmic protein tyrosine kinase activity|negative regulation of cytoplasmic protein tyrosine kinase activity|negative regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down regulation of Bruton's tyrosine kinase activity						nc	2015-03-05T16:34:41Z						biological_process											owl:Class	
GO:0062232	biolink:NamedThing	prostanoid catabolic process	The chemical reactions and pathways resulting in the breakdown of prostanoids.	got7fsn_ti							dph	2020-03-23T15:17:02Z						biological_process											owl:Class	
GO:1902229	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.	got7fsn_ti	regulation of DNA damage response, signal transduction resulting in induction of apoptosis						rl	2013-06-14T09:39:52Z						biological_process											owl:Class	
GO:1905381	biolink:NamedThing	negative regulation of snRNA transcription by RNA polymerase II	Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.	got7fsn_ti	down-regulation of snRNA transcription from RNA polymerase II promoter|downregulation of snRNA transcription from Pol II promoter|inhibition of snRNA transcription from Pol II promoter|inhibition of snRNA transcription from RNA polymerase II promoter|down-regulation of snRNA transcription from Pol II promoter|downregulation of snRNA transcription from RNA polymerase II promoter|down regulation of snRNA transcription from RNA polymerase II promoter|negative regulation of snRNA transcription from RNA polymerase II promoter|down regulation of snRNA transcription from Pol II promoter|negative regulation of snRNA transcription from Pol II promoter						bhm	2016-08-18T13:39:27Z						biological_process											owl:Class	
GO:0001305	biolink:NamedThing	obsolete progressive alteration of chromatin involved in chronological cell aging	OBSOLETE. A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells.	got7fsn_ti	progressive alteration of chromatin during chronological cell ageing|progressive alteration of chromatin during chronological cell aging	https://github.com/geneontology/go-ontology/issues/18632			This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398				True				biological_process											owl:Class	
GO:1904450	biolink:NamedThing	positive regulation of aspartate secretion	Any process that activates or increases the frequency, rate or extent of aspartate secretion.	got7fsn_ti	up regulation of aspartate secretion|up-regulation of aspartate secretion|activation of aspartate secretion|upregulation of aspartate secretion						sl	2015-07-07T20:57:10Z						biological_process											owl:Class	
GO:0015029	biolink:NamedThing	obsolete internalization receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	internalization receptor activity				This term was made obsolete because internalization is a process, not a ligand to which a receptor might bind.					True				molecular_function											owl:Class	
GO:0009688	biolink:NamedThing	abscisic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.	got7fsn_ti	abscisic acid synthesis|abscisic acid anabolism|abscisic acid formation|abscisic acid biosynthesis											MetaCyc:PWY-695		biological_process											owl:Class	
GO:0005203	biolink:NamedThing	obsolete proteoglycan	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	proteoglycan				This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function.					True				molecular_function											owl:Class	
GO:0014075	biolink:NamedThing	response to amine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.	got7fsn_ti	response to amine stimulus													biological_process											owl:Class	
GO:0005028	biolink:NamedThing	obsolete CD40 receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	CD40 receptor activity				This term was made obsolete because it describes the receptor type, and not an activity.	GO:0042615				True				molecular_function											owl:Class	
GO:1904710	biolink:NamedThing	positive regulation of granulosa cell apoptotic process	Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process.	got7fsn_ti	positive regulation of granulosa cell apoptosis|upregulation of granulosa cell of ovary apoptosis|upregulation of granulosa cell of ovary apoptotic process|upregulation of granulosa cell apoptotic process|up regulation of granulosa cell apoptotic process|activation of granulosa cell of ovary apoptosis|up-regulation of granulosa cell of ovary apoptosis|positive regulation of granulosa cell of ovary apoptosis|up-regulation of granulosa cell apoptotic process|activation of granulosa cell apoptosis|up-regulation of granulosa cell apoptosis|up regulation of granulosa cell of ovary apoptotic process|up regulation of granulosa cell of ovary apoptosis|activation of granulosa cell of ovary apoptotic process|up-regulation of granulosa cell of ovary apoptotic process|positive regulation of granulosa cell of ovary apoptotic process|activation of granulosa cell apoptotic process|upregulation of granulosa cell apoptosis|up regulation of granulosa cell apoptosis						sl	2015-10-01T16:09:51Z						biological_process											owl:Class	
GO:1904193	biolink:NamedThing	negative regulation of cholangiocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process.	got7fsn_ti	down-regulation of epithelial cell of bile duct apoptotic process|downregulation of cholangiocyte apoptosis|downregulation of epithelial cell of bile duct apoptotic process|negative regulation of epithelial cell of bile duct apoptotic process|down-regulation of epithelial cell of bile duct apoptosis|down regulation of cholangiocyte apoptosis|down-regulation of cholangiocyte apoptosis|downregulation of epithelial cell of bile duct apoptosis|inhibition of cholangiocyte apoptosis|downregulation of cholangiocyte apoptotic process|negative regulation of epithelial cell of bile duct apoptosis|inhibition of cholangiocyte apoptotic process|inhibition of epithelial cell of bile duct apoptotic process|down regulation of epithelial cell of bile duct apoptosis|down regulation of epithelial cell of bile duct apoptotic process|inhibition of epithelial cell of bile duct apoptosis|down-regulation of cholangiocyte apoptotic process|down regulation of cholangiocyte apoptotic process|negative regulation of cholangiocyte apoptosis						sl	2015-05-06T15:25:55Z						biological_process											owl:Class	
GO:0046299	biolink:NamedThing	obsolete 2,4-dichlorophenoxyacetic acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.	got7fsn_ti	2,4-dichlorophenoxyacetic acid biosynthetic process|2,4-dichlorophenoxyacetic acid anabolism|2,4-dichlorophenoxyacetic acid biosynthesis|2,4-dichlorophenoxyacetic acid synthesis|2,4-dichlorophenoxyacetic acid formation			GO:0018901	This term was made obsolete because 2,4-dichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0044681	biolink:NamedThing	sulfopyruvate decarboxylase complex	A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis.	got7fsn_ti							jl	2012-08-09T11:12:47Z						cellular_component											owl:Class	
GO:0010928	biolink:NamedThing	regulation of auxin mediated signaling pathway	Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.	got7fsn_ti	regulation of auxin mediated signalling pathway													biological_process											owl:Class	
GO:2000386	biolink:NamedThing	positive regulation of ovarian follicle development	Any process that activates or increases the frequency, rate or extent of ovarian follicle development.	got7fsn_ti	positive regulation of follicular phase						yaf	2011-02-16T02:21:21Z						biological_process											owl:Class	
GO:0019285	biolink:NamedThing	glycine betaine biosynthetic process from choline	The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.	got7fsn_ti	N-trimethylglycine biosynthesis from choline|glycine betaine synthesis from choline|N-trimethylglycine biosynthetic process from choline|choline oxidation|glycine betaine formation from choline|glycine betaine anabolism from choline											MetaCyc:CHOLINE-BETAINE-ANA-PWY|MetaCyc:P542-PWY|MetaCyc:BETSYN-PWY		biological_process											owl:Class	
GO:1904129	biolink:NamedThing	positive regulation of convergent extension involved in somitogenesis	Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis.	got7fsn_ti	up-regulation of convergent extension involved in somitogenesis|upregulation of convergent extension involved in somitogenesis|up regulation of convergent extension involved in somitogenesis|activation of convergent extension involved in somitogenesis						dph	2015-04-10T21:13:15Z						biological_process											owl:Class	
GO:1905932	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.	got7fsn_ti	upregulation of VSMC differentiation involved in phenotypic dimorphism|activation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|upregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|positive regulation of VSMC differentiation involved in phenotypic dimorphism|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|upregulation of VSMC differentiation involved in phenotypic switching|activation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|positive regulation of VSMC differentiation involved in phenotypic switching|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of VSMC differentiation involved in phenotypic switching|activation of VSMC differentiation involved in phenotypic dimorphism|up-regulation of VSMC differentiation involved in phenotypic dimorphism|up regulation of VSMC differentiation involved in phenotypic dimorphism|activation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up regulation of VSMC differentiation involved in phenotypic switching|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|activation of vascular smooth muscle cell differentiation involved in phenotypic switching|activation of VSMC differentiation involved in phenotypic switching|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|upregulation of vascular smooth muscle cell differentiation involved in phenotypic switching						rph	2017-02-09T09:21:17Z						biological_process											owl:Class	
GO:1904773	biolink:NamedThing	obsolete cellular response to tetrachloromethane	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus.	got7fsn_ti	cellular response to carbon tetrachloride|cellular response to CCL4				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-10-28T20:59:21Z		True				biological_process											owl:Class	
GO:0035109	biolink:NamedThing	obsolete imaginal disc-derived limb morphogenesis	OBSOLETE. The process in which the anatomical structures of limbs that are derived from an imaginal disc are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	imaginal disc-derived limb morphogenesis				This term was made obsolete because the term 'limb' is not widely used in the insect community. In GO, 'limb' is used to describe the vertebrate hindlimbs and forelimbs.	GO:0035114				True				biological_process											owl:Class	
GO:1904953	biolink:NamedThing	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.	got7fsn_ti	frizzled signalling pathway involved in mDA neuron differentiation|Wnt signaling pathway involved in midbrain dopaminergic neuron production|Wingless signaling pathway involved in mDA neuron differentiation|Wnt-activated signaling pathway involved in mDA neuron differentiation|Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|frizzled signalling pathway involved in midbrain dopaminergic neuron production|Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signalling pathway involved in midbrain DA neurogenesis|frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|Wingless signalling pathway involved in midbrain dopaminergic neuron production|Wnt-mediated midbrain DA neuron differentiation|Wnt receptor signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway involved in midbrain DA neurogenesis|Wnt signaling pathway involved in mDA neuron differentiation|Wingless signalling pathway involved in midbrain DA neurogenesis|Wg signaling pathway involved in mDA neuron differentiation|frizzled signaling pathway involved in midbrain DA neurogenesis|Wg signalling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|frizzled signaling pathway involved in mDA neuron differentiation|Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway involved in mDA neuron differentiation|Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|Wingless signaling pathway involved in midbrain DA neurogenesis|Wnt signaling pathway involved in midbrain DA neurogenesis|Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|Wingless signalling pathway involved in mDA neuron differentiation|Wingless signaling pathway involved in midbrain dopaminergic neuron production|frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|Wg signaling pathway involved in midbrain dopaminergic neuron production|Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|Wg signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|Wg signalling pathway involved in mDA neuron differentiation|Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|frizzled signaling pathway involved in midbrain dopaminergic neuron production|Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|Wg signalling pathway involved in midbrain DA neurogenesis						bf	2016-02-08T12:02:07Z						biological_process											owl:Class	
GO:1901044	biolink:NamedThing	protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process	Any protein polyubiquitination that is involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process.	got7fsn_ti							al	2012-06-26T10:59:04Z						biological_process											owl:Class	
GO:0070020	biolink:NamedThing	obsolete transforming growth factor beta1-type II receptor complex	OBSOLETE. A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer.	got7fsn_ti	TGF-beta1-type II receptor complex|TGF-beta receptor II-TGF-beta1 complex	https://github.com/geneontology/go-ontology/issues/12676			This term was made obsolete because it does not represent a physiological complex.					True				cellular_component											owl:Class	
GO:0097055	biolink:NamedThing	agmatine biosynthetic process	The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase.	got7fsn_ti	agmatine formation|agmatine synthesis|agmatine biosynthesis|agmatine anabolism						pr	2011-05-25T03:56:17Z						biological_process											owl:Class	
GO:1904941	biolink:NamedThing	positive regulation of DNA nucleotidylexotransferase activity	Any process that activates or increases the frequency, rate or extent of DNA nucleotidylexotransferase activity.	got7fsn_ti	up regulation of terminal deoxynucleotidyltransferase activity|activation of addase activity|activation of terminal deoxynucleotide transferase activity|activation of DNA nucleotidylexotransferase activity|upregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|up-regulation of deoxyribonucleic nucleotidyltransferase activity|up regulation of addase activity|upregulation of deoxyribonucleic acid nucleotidyltransferase activity|up-regulation of addase activity|up-regulation of terminal deoxynucleotidyltransferase activity|up regulation of TdT|activation of terminal deoxynucleotidyltransferase activity|up-regulation of deoxyribonucleic acid nucleotidyltransferase activity|positive regulation of deoxyribonucleic acid nucleotidyltransferase activity|upregulation of terminal deoxyribonucleotidyltransferase activity|up-regulation of DNA nucleotidylexotransferase activity|positive regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|activation of deoxyribonucleic nucleotidyltransferase activity|upregulation of TdT|up regulation of terminal transferase activity|upregulation of terminal addition enzyme activity|up regulation of deoxyribonucleic acid nucleotidyltransferase activity|positive regulation of terminal deoxynucleotide transferase activity|activation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|up regulation of DNA nucleotidylexotransferase activity|positive regulation of terminal addition enzyme activity|up regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|positive regulation of addase activity|up regulation of deoxyribonucleic nucleotidyltransferase activity|up-regulation of terminal addition enzyme activity|up-regulation of deoxynucleotidyl terminal transferase activity|positive regulation of terminal transferase activity|upregulation of terminal deoxynucleotide transferase activity|up regulation of terminal deoxynucleotide transferase activity|upregulation of DNA nucleotidylexotransferase activity|up-regulation of TdT|up-regulation of terminal transferase activity|positive regulation of terminal deoxyribonucleotidyltransferase activity|activation of terminal deoxyribonucleotidyltransferase activity|upregulation of deoxyribonucleic nucleotidyltransferase activity|activation of TdT|up regulation of deoxynucleotidyl terminal transferase activity|upregulation of terminal deoxynucleotidyltransferase activity|activation of deoxynucleotidyl terminal transferase activity|up regulation of terminal addition enzyme activity|activation of terminal addition enzyme activity|up regulation of terminal deoxyribonucleotidyltransferase activity|up-regulation of terminal deoxyribonucleotidyltransferase activity|upregulation of addase activity|up-regulation of terminal deoxynucleotide transferase activity|activation of deoxyribonucleic acid nucleotidyltransferase activity|positive regulation of deoxyribonucleic nucleotidyltransferase activity|up-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|positive regulation of terminal deoxynucleotidyltransferase activity|positive regulation of deoxynucleotidyl terminal transferase activity|upregulation of terminal transferase activity|positive regulation of TdT|upregulation of deoxynucleotidyl terminal transferase activity|activation of terminal transferase activity						bc	2016-02-02T15:16:12Z						biological_process											owl:Class	
GO:1904271	biolink:NamedThing	L-proline import across plasma membrane	The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-proline import into cell						mah	2015-01-16T14:36:01Z			GO:1903809			biological_process											owl:Class	
GO:1905722	biolink:NamedThing	regulation of trypanothione biosynthetic process	Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process.	got7fsn_ti	regulation of trypanothione formation|regulation of trypanothione anabolism|regulation of trypanothione synthesis|regulation of trypanothione biosynthesis						rz	2016-11-25T14:44:34Z						biological_process											owl:Class	
GO:0008846	biolink:NamedThing	obsolete endopeptidase La activity	OBSOLETE. Catalysis of the hydrolysis of large proteins such as globin, casein and denatured serum albumin, in presence of ATP.	got7fsn_ti	ATP-dependent serine proteinase activity|endopeptidase La activity|ATP-dependent lon proteinase|Escherichia coli serine proteinase La|gene lon protease activity|serine protease La|PIM1 protease activity|lon proteinase|protease La|Escherichia coli proteinase La|PIM1 proteinase activity|gene lon proteins|proteinase La|ATP-dependent protease La activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
PR:000001549	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901530	biolink:NamedThing	response to hypochlorite	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus.	got7fsn_ti							pr	2012-10-24T07:12:21Z						biological_process											owl:Class	
GO:0044454	biolink:NamedThing	obsolete nuclear chromosome part	OBSOLETE. Any constituent part of a nuclear chromosome, a chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0000228				True				cellular_component											owl:Class	
GO:0052427	biolink:NamedThing	obsolete modulation by host of symbiont peptidase activity	OBSOLETE. The process in which an organism effects a change in symbiont peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by host of symbiont protease activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0090022	biolink:NamedThing	regulation of neutrophil chemotaxis	Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	got7fsn_ti							tb	2009-08-03T10:09:34Z						biological_process											owl:Class	
GO:0046791	biolink:NamedThing	obsolete suppression by virus of host complement neutralization	OBSOLETE. Any viral process that results in the inhibition of complement neutralization of the host cell.	got7fsn_ti	suppression by virus of host complement neutralization|negative regulation by virus of host complement neutralization				This term was made obsolete because the meaning of the term is unclear. It most likely refers to inhibiting the process by which a virus particle is neutralized by the host cell in a complement-dependent manner.					True				biological_process											owl:Class	
GO:1902236	biolink:NamedThing	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.	got7fsn_ti	down regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of ER stress-induced apoptosis|down-regulation of endoplasmic reticulum stress-induced apoptosis|down regulation of endoplasmic reticulum stress-induced apoptosis|inhibition of apoptosis triggered by ER stress|negative regulation of apoptosis in response to ER stress|downregulation of ER stress-induced apoptosis|downregulation of endoplasmic reticulum stress-induced apoptosis|down regulation of ER stress-induced apoptosis|inhibition of ER stress-induced apoptosis|down-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|inhibition of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down regulation of apoptosis in response to ER stress|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|downregulation of apoptosis triggered by ER stress|down regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|downregulation of apoptosis in response to ER stress|negative regulation of endoplasmic reticulum stress-induced apoptosis|down-regulation of apoptosis in response to ER stress|downregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|down-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|inhibition of apoptosis in response to ER stress|down regulation of apoptosis triggered by ER stress|down-regulation of apoptosis triggered by ER stress|down-regulation of ER stress-induced apoptosis|negative regulation of apoptosis triggered by ER stress|inhibition of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|inhibition of endoplasmic reticulum stress-induced apoptosis						rl	2013-06-18T15:19:43Z						biological_process											owl:Class	
GO:1904189	biolink:NamedThing	positive regulation of transformation of host cell by virus	Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus.	got7fsn_ti	activation of viral transformation|upregulation of transformation of host cell by virus|up regulation of viral transformation of host cell|upregulation of viral transformation of host cell|positive regulation of viral transformation of host cell|activation of viral transformation of host cell|up-regulation of viral transformation|positive regulation of viral transformation|up-regulation of viral transformation of host cell|up-regulation of transformation of host cell by virus|up regulation of transformation of host cell by virus|upregulation of viral transformation|activation of transformation of host cell by virus|up regulation of viral transformation						pga	2015-05-05T15:30:11Z						biological_process											owl:Class	
GO:1900494	biolink:NamedThing	regulation of butyryl-CoA biosynthetic process from acetyl-CoA	Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.	got7fsn_ti	regulation of butyryl-CoA biosynthesis from acetyl-CoA						tt	2012-05-02T03:51:38Z						biological_process											owl:Class	
GO:0060744	biolink:NamedThing	mammary gland branching involved in thelarche	The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	got7fsn_ti	mammary gland branching involved in puberty						dph	2009-06-22T08:12:17Z						biological_process											owl:Class	
GO:0043948	biolink:NamedThing	obsolete induction by symbiont of host catalytic activity	OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host enzyme activity|up-regulation by symbiont of host enzyme activity|up regulation by symbiont of host enzyme activity|positive regulation by symbiont of host catalytic activity|activation of host enzyme activity|upregulation by symbiont of host enzyme activity|activation by symbiont of host enzyme activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1904234	biolink:NamedThing	positive regulation of aconitate hydratase activity	Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity.	got7fsn_ti	up-regulation of aconitase activity|positive regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|up regulation of cis-aconitase activity|up regulation of citrate(isocitrate) hydro-lyase activity|up regulation of aconitate hydratase activity|upregulation of citrate(isocitrate) hydro-lyase activity|upregulation of aconitate hydratase activity|up-regulation of cis-aconitase activity|activation of aconitate hydratase activity|upregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|upregulation of cis-aconitase activity|positive regulation of cis-aconitase activity|up regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|positive regulation of aconitase activity|up regulation of aconitase activity|activation of aconitase activity|activation of citrate(isocitrate) hydro-lyase activity|positive regulation of citrate(isocitrate) hydro-lyase activity|upregulation of aconitase activity|up-regulation of aconitate hydratase activity|activation of cis-aconitase activity|up-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|up-regulation of citrate(isocitrate) hydro-lyase activity|activation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)						rl	2015-05-15T09:55:29Z						biological_process											owl:Class	
GO:1900485	biolink:NamedThing	positive regulation of protein targeting to vacuolar membrane	Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane.	got7fsn_ti	up regulation of protein targeting to vacuolar membrane|up-regulation of protein targeting to vacuolar membrane|upregulation of protein targeting to vacuolar membrane|activation of protein targeting to vacuolar membrane						al	2012-05-02T10:13:41Z						biological_process											owl:Class	
GO:1900033	biolink:NamedThing	negative regulation of trichome patterning	Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning.	got7fsn_ti	negative regulation of trichome pattern formation|down regulation of trichome distribution|negative regulation of trichome spacing|down-regulation of trichome distribution|inhibition of trichome pattern specification|downregulation of trichome pattern specification|downregulation of trichome distribution|downregulation of trichome pattern formation|down regulation of trichome pattern formation|negative regulation of trichome pattern specification|down-regulation of trichome pattern specification|inhibition of trichome pattern formation|down regulation of trichome spacing|down-regulation of trichome patterning|down regulation of trichome patterning|inhibition of trichome patterning|downregulation of trichome spacing|down regulation of trichome pattern biosynthesis|downregulation of trichome patterning|down-regulation of trichome pattern biosynthesis|negative regulation of trichome pattern biosynthesis|down regulation of trichome pattern specification|inhibition of trichome distribution|downregulation of trichome pattern biosynthesis|inhibition of trichome pattern biosynthesis|down-regulation of trichome pattern formation|down-regulation of trichome spacing|negative regulation of trichome distribution|inhibition of trichome spacing						tb	2012-01-13T11:10:50Z						biological_process											owl:Class	
GO:1905175	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell dedifferentiation	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.	got7fsn_ti	inhibition of vascular smooth muscle cell dedifferentiation|down-regulation of vascular smooth muscle cell dedifferentiation|negative regulation of vascular smooth muscle cell dedifferentiation|down regulation of vascular smooth muscle cell dedifferentiation|downregulation of vascular smooth muscle cell dedifferentiation						rph	2016-05-03T12:32:05Z						biological_process											owl:Class	
GO:0070484	biolink:NamedThing	dehydro-D-arabinono-1,4-lactone metabolic process	The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.	got7fsn_ti	dehydro-D-arabinono-1,4-lactone metabolism													biological_process											owl:Class	
GO:1902517	biolink:NamedThing	glycerol-3-phosphate-transporting ATPase complex	A protein complex which is capable of glycerol-3-phosphate-transporting ATPase activity.	got7fsn_ti					An example of this is UgpB in E. coli in PMID:23013274.		bhm	2013-11-27T16:53:33Z						cellular_component											owl:Class	
GO:1900280	biolink:NamedThing	negative regulation of CD4-positive, alpha-beta T cell costimulation	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.	got7fsn_ti	down-regulation of CD4-positive, alpha beta T cell costimulation|downregulation of CD4-positive, alpha beta T cell costimulation|inhibition of CD4-positive, alpha beta T cell costimulation|negative regulation of CD4-positive, alpha beta T cell costimulation|down regulation of CD4-positive, alpha beta T cell costimulation						rl	2012-04-04T08:56:26Z						biological_process											owl:Class	
GO:0014060	biolink:NamedThing	regulation of epinephrine secretion	Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.	got7fsn_ti	regulation of adrenaline secretion													biological_process											owl:Class	
GO:0061404	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to increased salt	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12739			This term was obsoleted because it represents a GO-CAM model.	GO:0045944|GO:0071472	dph	2012-01-10T03:20:40Z		True				biological_process											owl:Class	
GO:0061261	biolink:NamedThing	mesenchymal to epithelial transition involved in mesonephros morphogenesis	A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.	got7fsn_ti	mesonephric mesenchyme to epithelial transition						dph	2010-08-30T02:35:15Z						biological_process											owl:Class	
GO:0006920	biolink:NamedThing	obsolete commitment to apoptosis	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	commitment to apoptosis				This term was made obsolete because more accurate terms were created.	GO:0006915				True				biological_process											owl:Class	
GO:1900184	biolink:NamedThing	negative regulation of xanthone-containing compound biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process.	got7fsn_ti	down-regulation of xanthone-containing compound formation|inhibition of xanthone-containing compound anabolism|down-regulation of xanthone biosynthetic process|negative regulation of xanthone-containing compound biosynthesis|downregulation of xanthone-containing compound anabolism|down-regulation of xanthone-containing compound synthesis|negative regulation of xanthone biosynthetic process|down-regulation of xanthone biosynthesis|negative regulation of xanthone biosynthesis|inhibition of xanthone-containing compound synthesis|negative regulation of xanthone-containing compound formation|down regulation of xanthone-containing compound anabolism|down-regulation of xanthone-containing compound anabolism|negative regulation of xanthone-containing compound anabolism|inhibition of xanthone-containing compound biosynthetic process|down regulation of xanthone biosynthesis|down regulation of xanthone-containing compound biosynthetic process|inhibition of xanthone biosynthetic process|inhibition of xanthone-containing compound formation|inhibition of xanthone-containing compound biosynthesis|down regulation of xanthone-containing compound synthesis|down-regulation of xanthone-containing compound biosynthetic process|down regulation of xanthone biosynthetic process|down regulation of xanthone-containing compound formation|down regulation of xanthone-containing compound biosynthesis|down-regulation of xanthone-containing compound biosynthesis|negative regulation of xanthone-containing compound synthesis|downregulation of xanthone biosynthesis|inhibition of xanthone biosynthesis|downregulation of xanthone-containing compound biosynthesis|downregulation of xanthone-containing compound formation|downregulation of xanthone biosynthetic process|negative regulation of xanthones anabolism|downregulation of xanthone-containing compound synthesis|downregulation of xanthone-containing compound biosynthetic process						di	2012-03-16T03:30:24Z						biological_process											owl:Class	
GO:0018135	biolink:NamedThing	obsolete peptidyl-cysteine cyclase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peptidyl-cysteine cyclase activity				This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists.					True		EC:4.2.1.-		molecular_function											owl:Class	
GO:2000768	biolink:NamedThing	positive regulation of nephron tubule epithelial cell differentiation	Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.	got7fsn_ti							yaf	2011-06-22T11:55:06Z						biological_process											owl:Class	
GO:0008607	biolink:NamedThing	phosphorylase kinase regulator activity	Modulation of the activity of the enzyme phosphorylase kinase.	got7fsn_ti	phosphorylase kinase, intrinsic regulator activity											EC:2.7.1.-		molecular_function											owl:Class	
GO:0036087	biolink:NamedThing	glutathione synthase complex	A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer.	got7fsn_ti	glutathione synthetase complex						bf	2012-01-05T04:29:20Z						cellular_component											owl:Class	
GO:1903878	biolink:NamedThing	11-deoxycorticosterone binding	Binding to 11-deoxycorticosterone.	got7fsn_ti							mr	2015-02-06T16:03:03Z						molecular_function											owl:Class	
GO:1901230	biolink:NamedThing	negative regulation of non-canonical Wnt signaling pathway via JNK cascade	Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.	got7fsn_ti	down-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|inhibition of non-canonical Wnt receptor signaling pathway via JNK cascade|negative regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|downregulation of non-canonical Wnt receptor signalling pathway via JNK cascade|downregulation of non-canonical Wnt receptor signaling pathway via JNK cascade|down regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|down regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|negative regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|down-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|negative regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|inhibition of non-canonical Wnt receptor signalling pathway via JNK cascade						vk	2012-08-07T14:14:39Z						biological_process											owl:Class	
GO:1904795	biolink:NamedThing	positive regulation of euchromatin binding	Any process that activates or increases the frequency, rate or extent of euchromatin binding.	got7fsn_ti	activation of euchromatin binding|up-regulation of euchromatin binding|up regulation of euchromatin binding|upregulation of euchromatin binding						nc	2015-11-09T11:43:19Z						biological_process											owl:Class	
GO:0042808	biolink:NamedThing	obsolete neuronal Cdc2-like kinase binding	OBSOLETE. Binding to neuronal Cdc2-like kinase, an enzyme involved in the regulation of neuronal differentiation and neuro-cytoskeleton dynamics.	got7fsn_ti	neuronal Cdc2-like kinase binding			GO:0019901	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:1901766	biolink:NamedThing	phosphinothricin biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphinothricin.	got7fsn_ti	phosphinothricin formation|phosphinothricin anabolism|phosphinothricin synthesis|phosphinothricin biosynthesis						yaf	2013-01-15T10:02:46Z						biological_process											owl:Class	
GO:2000284	biolink:NamedThing	positive regulation of cellular amino acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.	got7fsn_ti	positive regulation of cellular amino acid biosynthesis|positive regulation of cellular amino acid synthesis|positive regulation of amino acid biosynthetic process|positive regulation of cellular amino acid anabolism|positive regulation of cellular amino acid formation						vw	2010-12-10T11:54:27Z						biological_process											owl:Class	
GO:1903337	biolink:NamedThing	positive regulation of vacuolar transport	Any process that activates or increases the frequency, rate or extent of vacuolar transport.	got7fsn_ti	upregulation of vacuolar transport|up-regulation of vacuolar transport|activation of vacuolar transport|up regulation of vacuolar transport						vw	2014-08-18T13:16:19Z						biological_process											owl:Class	
GO:1904798	biolink:NamedThing	positive regulation of core promoter binding	Any process that activates or increases the frequency, rate or extent of core promoter binding.	got7fsn_ti	upregulation of core promoter binding|up-regulation of core promoter binding|up regulation of core promoter binding|activation of core promoter binding						nc	2015-11-09T12:32:38Z						biological_process											owl:Class	
GO:0046474	biolink:NamedThing	glycerophospholipid biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.	got7fsn_ti	glycerophospholipid anabolism|phosphoglyceride biosynthesis|glycerophospholipid synthesis|glycerophospholipid biosynthesis|glycerophospholipid formation|phosphoglyceride biosynthetic process													biological_process											owl:Class	
GO:0030842	biolink:NamedThing	regulation of intermediate filament depolymerization	Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament.	got7fsn_ti														biological_process											owl:Class	
GO:1902223	biolink:NamedThing	erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid.	got7fsn_ti	erythrose 4-phosphate/phosphoenolpyruvate family amino acid formation|erythrose 4-phosphate/phosphoenolpyruvate family amino acid synthesis|erythrose 4-phosphate/phosphoenolpyruvate family amino acid anabolism|erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthesis						pr	2013-06-13T10:37:49Z						biological_process											owl:Class	
GO:0047859	biolink:NamedThing	obsolete dihydroxyphenylalanine ammonia-lyase activity	OBSOLETE. Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine = trans-caffeate + NH3.	got7fsn_ti	dihydroxyphenylalanine ammonia-lyase activity|3,4-dihydroxy-L-phenylalanine ammonia-lyase (trans-caffeate-forming)|beta-(3,4-dihydroxyphenyl)-L-alanine (DOPA) ammonia-lyase activity|3,4-dihydroxy-L-phenylalanine ammonia-lyase activity				This term was made obsolete because the corresponding EC reaction (EC:4.3.1.11) has been deleted from the EC.					True		EC:4.3.1.11		molecular_function											owl:Class	
GO:1900489	biolink:NamedThing	positive regulation of [2Fe-2S] cluster assembly	Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly.	got7fsn_ti	up-regulation of [2Fe-2S] cluster assembly|up regulation of [2Fe-2S] cluster assembly|activation of [2Fe-2S] cluster biosynthetic process|positive regulation of 2Fe-2S cluster assembly|upregulation of [2Fe-2S] cluster biosynthetic process|up-regulation of 2Fe-2S cluster assembly|activation of [2Fe-2S] cluster assembly|activation of 2Fe-2S cluster assembly|up regulation of 2Fe-2S cluster assembly|up regulation of [2Fe-2S] cluster biosynthetic process|upregulation of [2Fe-2S] cluster assembly|upregulation of 2Fe-2S cluster assembly|up-regulation of [2Fe-2S] cluster biosynthetic process|positive regulation of [2Fe-2S] cluster biosynthetic process						tt	2012-05-02T01:22:40Z						biological_process											owl:Class	
GO:0010373	biolink:NamedThing	negative regulation of gibberellin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.	got7fsn_ti	negative regulation of gibberellic acid biosynthetic process													biological_process											owl:Class	
GO:1905129	biolink:NamedThing	endocannabinoid signaling pathway involved in trans-synaptic signaling	Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid.	got7fsn_ti	endocannabinoid signalling pathway involved in trans-synaptic signaling by endocannabinoid						dos	2016-04-12T10:45:13Z						biological_process											owl:Class	
GO:1904963	biolink:NamedThing	regulation of phytol biosynthetic process	Any process that modulates the frequency, rate or extent of phytol biosynthetic process.	got7fsn_ti	regulation of phytol formation|regulation of phytol anabolism|regulation of phytol synthesis|regulation of phytol biosynthesis						tb	2016-02-11T00:41:51Z						biological_process											owl:Class	
GO:1905306	biolink:NamedThing	positive regulation of cardiac myofibril assembly	Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly.	got7fsn_ti	positive regulation of heart myofibril assembly|activation of cardiac myofibril development|activation of cardiac myofibril assembly|up-regulation of cardiac myofibril assembly|up regulation of cardiac myofibril assembly|activation of heart myofibril assembly|up regulation of heart myofibril assembly|upregulation of cardiac myofibril morphogenesis|activation of cardiac myofibril morphogenesis|positive regulation of cardiac myofibril morphogenesis|positive regulation of cardiac myofibril development|upregulation of cardiac myofibril development|up regulation of cardiac myofibril development|up-regulation of cardiac myofibril morphogenesis|up regulation of cardiac myofibril morphogenesis|up-regulation of heart myofibril assembly|upregulation of heart myofibril assembly|upregulation of cardiac myofibril assembly|up-regulation of cardiac myofibril development						rl	2016-07-06T10:02:07Z						biological_process											owl:Class	
GO:0140433	biolink:NamedThing	regulation of protein localization to meiotic spindle pole body	Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body.	got7fsn_ti							pg	2020-02-24T13:26:53Z						biological_process											owl:Class	
GO:0002922	biolink:NamedThing	positive regulation of humoral immune response	Any process that activates or increases the frequency, rate, or extent of a humoral immune response.	got7fsn_ti	up-regulation of humoral immune response|up regulation of humoral immune response|upregulation of humoral immune response|activation of humoral immune response|stimulation of humoral immune response													biological_process											owl:Class	
GO:1904907	biolink:NamedThing	regulation of maintenance of mitotic sister chromatid cohesion, telomeric	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.	got7fsn_ti	regulation of maintenance of mitotic sister chromatin cohesion at telomere|regulation of maintenance of telomeric mitotic sister chromatin cohesion|regulation of maintenance of sister chromatin cohesion at telomere at mitosis						rph	2016-01-19T10:30:29Z						biological_process											owl:Class	
GO:0097328	biolink:NamedThing	response to carboplatin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.	got7fsn_ti							pr	2012-06-12T10:50:34Z						biological_process											owl:Class	
GO:0036226	biolink:NamedThing	obsolete mitotic cell cycle arrest in response to glucose starvation	OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of glucose.	got7fsn_ti	cell cycle arrest in response to glucose starvation				This term was made obsolete because it is superfluous, as only the more specific 'mitotic G2 cell cycle arrest in response to glucose starvation' has been observed.		bf	2012-05-09T02:43:22Z		True				biological_process											owl:Class	
GO:1903816	biolink:NamedThing	positive regulation of collecting lymphatic vessel constriction	Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction.	got7fsn_ti	up regulation of collecting lymphatic vessel constriction|upregulation of lymphatic vessel myogenic constriction|up-regulation of collecting lymphatic vessel constriction|activation of lymphatic vessel myogenic constriction|upregulation of collecting lymphatic vessel constriction|up regulation of lymphatic vessel myogenic constriction|activation of collecting lymphatic vessel constriction|positive regulation of lymphatic vessel myogenic constriction|up-regulation of lymphatic vessel myogenic constriction						sl	2015-01-16T17:02:08Z						biological_process											owl:Class	
GO:0044041	biolink:NamedThing	obsolete multi-organism carbohydrate catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, involving more than one organism.	got7fsn_ti	multi-organism carbohydrate catabolism|multi-organism carbohydrate degradation|multi-organism carbohydrate breakdown	https://github.com/geneontology/go-ontology/issues/19769			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0080035	biolink:NamedThing	2-hydroxy-but-3-enyl glucosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables.	got7fsn_ti	progoitrin biosynthesis|2-hydroxy-but-3-enyl glucosinolate anabolism|progoitrin synthesis|2-hydroxy-but-3-enyl glucosinolate synthesis|progoitrin biosynthetic process|2-hydroxy-but-3-enyl glucosinolate formation|2-hydroxy-but-3-enyl glucosinolate biosynthesis													biological_process											owl:Class	
CL:1000618	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902530	biolink:NamedThing	positive regulation of protein linear polyubiquitination	Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination.	got7fsn_ti	up-regulation of protein linear polyubiquitination|upregulation of M1 linkage|up-regulation of M1 linkage|activation of protein linear polyubiquitination|up regulation of M1 linkage|up regulation of protein linear polyubiquitination|upregulation of protein linear polyubiquitination|activation of M1 linkage|positive regulation of M1 linkage				An example is BIRC2 (UniProt ID Q13490) in PMID:21931591.		ppm	2013-12-02T10:03:18Z						biological_process											owl:Class	
GO:0051088	biolink:NamedThing	obsolete PMA-inducible membrane protein ectodomain proteolysis	OBSOLETE. The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs after induction by phorbol-12-myristate-13-acetate (PMA), a protein kinase C agonist.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19855			This term was obsoleted because it represents an assay to induce PKC.					True				biological_process											owl:Class	
GO:1902364	biolink:NamedThing	negative regulation of protein localization to spindle pole body	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body.	got7fsn_ti	down-regulation of protein localisation to spindle pole body|down regulation of protein localisation to spindle pole body|inhibition of protein localisation to spindle pole body|downregulation of protein localisation to spindle pole body|negative regulation of protein localisation to spindle pole body|down regulation of protein localization to spindle pole body|inhibition of protein localization to spindle pole body|downregulation of protein localization to spindle pole body|down-regulation of protein localization to spindle pole body						vw	2013-08-15T16:38:23Z						biological_process											owl:Class	
GO:0017120	biolink:NamedThing	obsolete polyphosphatidylinositol phosphatase activity	OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization.	got7fsn_ti	polyphosphatidylinositol phosphatase activity|polyphosphoinositide phosphatase activity				This term was made obsolete because it represents a gene product.	GO:0004438|GO:0034593|GO:0043812				True				molecular_function											owl:Class	
GO:1902090	biolink:NamedThing	regulation of fumagillin biosynthetic process	Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process.	got7fsn_ti	regulation of fumagillin formation|regulation of fumagillin biosynthesis|regulation of fumagillin synthesis|regulation of fumagillin anabolism						di	2013-04-27T03:44:59Z						biological_process											owl:Class	
GO:1905497	biolink:NamedThing	negative regulation of triplex DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding.	got7fsn_ti	inhibition of triplex DNA binding|down regulation of triplex DNA binding|down-regulation of triplex DNA binding|downregulation of triplex DNA binding						ans	2016-09-26T14:57:17Z						biological_process											owl:Class	
GO:1903433	biolink:NamedThing	regulation of constitutive secretory pathway	Any process that modulates the frequency, rate or extent of constitutive secretory pathway.	got7fsn_ti							als	2014-09-15T15:07:31Z						biological_process											owl:Class	
GO:1901205	biolink:NamedThing	obsolete negative regulation of adrenergic receptor signaling pathway involved in heart process	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.	got7fsn_ti	inhibition of beta-adrenergic receptor signalling pathway involved in heart process|downregulation of adrenergic receptor signaling pathway involved in heart process|down-regulation of adrenergic receptor signalling pathway involved in heart process|down regulation of adrenergic receptor signaling pathway involved in heart process|negative regulation of adrenergic receptor signalling pathway involved in heart process|negative regulation of beta-adrenergic receptor signalling pathway involved in heart process|down-regulation of adrenergic receptor signaling pathway involved in heart process|down regulation of beta-adrenergic receptor signalling pathway involved in heart process|down regulation of adrenergic receptor signalling pathway involved in heart process|inhibition of adrenergic receptor signalling pathway involved in heart process|downregulation of adrenergic receptor signalling pathway involved in heart process|downregulation of beta-adrenergic receptor signalling pathway involved in heart process|down-regulation of beta-adrenergic receptor signalling pathway involved in heart process|inhibition of adrenergic receptor signaling pathway involved in heart process	https://github.com/geneontology/go-ontology/issues/14733			This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		hjd	2012-07-30T18:33:14Z		True				biological_process											owl:Class	
GO:0061001	biolink:NamedThing	regulation of dendritic spine morphogenesis	Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	got7fsn_ti							dph	2010-01-20T09:31:52Z						biological_process											owl:Class	
GO:1903856	biolink:NamedThing	regulation of cytokinin dehydrogenase activity	Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity.	got7fsn_ti	regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|regulation of cytokinin oxidase activity						tb	2015-01-30T00:33:51Z						biological_process											owl:Class	
GO:1901754	biolink:NamedThing	vitamin D3 catabolic process	The chemical reactions and pathways resulting in the breakdown of vitamin D3.	got7fsn_ti	calciol degradation|calciol catabolic process|vitamin D3 catabolism|vitamin D3 breakdown|cholecalciferol catabolism|vitamin D3 degradation|calciol breakdown|cholecalciferol catabolic process|calciol catabolism						yaf	2013-01-14T11:11:04Z						biological_process											owl:Class	
GO:1904964	biolink:NamedThing	positive regulation of phytol biosynthetic process	Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process.	got7fsn_ti	upregulation of phytol synthesis|upregulation of phytol biosynthesis|up regulation of phytol biosynthesis|positive regulation of phytol synthesis|up regulation of phytol anabolism|up-regulation of phytol biosynthetic process|up-regulation of phytol biosynthesis|up-regulation of phytol anabolism|up-regulation of phytol formation|positive regulation of phytol biosynthesis|activation of phytol biosynthetic process|positive regulation of phytol anabolism|up-regulation of phytol synthesis|upregulation of phytol anabolism|activation of phytol formation|activation of phytol anabolism|activation of phytol biosynthesis|up regulation of phytol formation|upregulation of phytol biosynthetic process|up regulation of phytol biosynthetic process|activation of phytol synthesis|up regulation of phytol synthesis|positive regulation of phytol formation|upregulation of phytol formation						tb	2016-02-11T00:42:07Z						biological_process											owl:Class	
GO:1905673	biolink:NamedThing	positive regulation of lysosome organization	Any process that activates or increases the frequency, rate or extent of lysosome organization.	got7fsn_ti	upregulation of lysosome organization|up-regulation of lysosome organisation|up regulation of lysosome organization and biogenesis|up-regulation of lysosome organization|upregulation of lysosome organization and biogenesis|activation of lysosome organization|positive regulation of lysosome organization and biogenesis|upregulation of lysosome organisation|up regulation of lysosome organisation|activation of lysosome organisation|positive regulation of lysosome organisation|up regulation of lysosome organization|activation of lysosome organization and biogenesis|up-regulation of lysosome organization and biogenesis						sl	2016-11-11T22:01:20Z						biological_process											owl:Class	
GO:0022014	biolink:NamedThing	obsolete radial glial cell division in subpallium	OBSOLETE. The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0002814	biolink:NamedThing	negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.	got7fsn_ti	down regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|downregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|down-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria													biological_process											owl:Class	
GO:0045888	biolink:NamedThing	obsolete regulation of transcription of homeotic gene (Polycomb group)	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the Polycomb group.	got7fsn_ti	regulation of transcription of homeotic gene (Polycomb group)				This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0006357				True				biological_process											owl:Class	
GO:0019522	biolink:NamedThing	ketogluconate metabolic process	The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.	got7fsn_ti	ketogluconate metabolism											MetaCyc:KETOGLUCONMET-PWY		biological_process											owl:Class	
GO:2000998	biolink:NamedThing	negative regulation of cellulose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process.	got7fsn_ti	negative regulation of cellulose breakdown|negative regulation of cellulose catabolism|negative regulation of cellulose degradation						tt	2011-08-08T03:21:26Z						biological_process											owl:Class	
GO:1905906	biolink:NamedThing	regulation of amyloid fibril formation	Any process that modulates the frequency, rate or extent of amyloid fibril formation.	got7fsn_ti	regulation of amyloid structure formation|regulation of amyloid structure assembly|regulation of amyloid fibril assembly				Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases  (PMID:22817896).		bc	2017-02-03T15:43:48Z						biological_process											owl:Class	
GO:0098524	biolink:NamedThing	neuromuscular junction of somatic muscle myotube	A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell.	got7fsn_ti							dos	2013-10-14T12:05:43Z						cellular_component											owl:Class	
GO:0075174	biolink:NamedThing	obsolete regulation of cAMP-mediated signaling in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont cAMP-mediated signal transduction in response to host|regulation of cAMP-mediated signal transduction in response to host|regulation of cAMP-mediated signalling in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0051058	biolink:NamedThing	negative regulation of small GTPase mediated signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.	got7fsn_ti	down regulation of small GTPase mediated signal transduction|negative regulation of small GTPase-mediated signal transduction|down-regulation of small GTPase mediated signal transduction|downregulation of small GTPase mediated signal transduction|inhibition of small GTPase mediated signal transduction													biological_process											owl:Class	
GO:0005364	biolink:NamedThing	maltose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in).	got7fsn_ti	maltose:hydrogen symporter activity|hydrogen/maltose transporter activity|maltose permease													molecular_function											owl:Class	
GO:1905371	biolink:NamedThing	ceramide phosphoethanolamine metabolic process	The chemical reactions and pathways involving ceramide phosphoethanolamine.	got7fsn_ti	ceramide phosphoethanolamine metabolism						hjd	2016-08-16T17:10:56Z						biological_process											owl:Class	
GO:0010812	biolink:NamedThing	negative regulation of cell-substrate adhesion	Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0034672	biolink:NamedThing	anterior/posterior pattern specification involved in pronephros development	The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.	got7fsn_ti	anterior/posterior pattern specification involved in pronephric kidney development													biological_process											owl:Class	
GO:0010663	biolink:NamedThing	positive regulation of striated muscle cell apoptotic process	Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.	got7fsn_ti	positive regulation of striated muscle cell apoptosis													biological_process											owl:Class	
GO:0021912	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0021520				True				biological_process											owl:Class	
GO:1900737	biolink:NamedThing	negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.	got7fsn_ti	negative regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of PLC-activating GPCR signaling pathway|negative regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of PLC-activating GPCR signaling pathway|down-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|downregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|inhibition of phospholipase C-activating dopamine receptor signaling pathway|down regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|inhibition of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down regulation of PLC-activating GPCR signaling pathway|down-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|negative regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|down-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|downregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|inhibition of phospholipase C-activating G-protein coupled receptor signaling pathway|downregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of phospholipase C-activating dopamine receptor signaling pathway|negative regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|inhibition of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of PLC-activating GPCR signaling pathway|down-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of PLC-activating GPCR signaling pathway|negative regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down regulation of phospholipase C-activating dopamine receptor signaling pathway|inhibition of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|inhibition of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of phospholipase C-activating dopamine receptor signaling pathway|down-regulation of phospholipase C-activating dopamine receptor signaling pathway|downregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|downregulation of phospholipase C-activating G-protein coupled receptor signaling pathway|negative regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)						rl	2012-05-28T10:07:48Z						biological_process											owl:Class	
CHEBI:17579	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014043	biolink:NamedThing	negative regulation of neuron maturation	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.	got7fsn_ti	down-regulation of neuron maturation|downregulation of neuron maturation|down regulation of neuron maturation|inhibition of neuron maturation													biological_process											owl:Class	
GO:0042326	biolink:NamedThing	negative regulation of phosphorylation	Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.	got7fsn_ti	down regulation of phosphorylation|inhibition of phosphorylation|downregulation of phosphorylation|down-regulation of phosphorylation													biological_process											owl:Class	
GO:0120262	biolink:NamedThing	negative regulation of heterochromatin organization	Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization.	got7fsn_ti	downregulation of heterochromatin organization|down regulation of heterochromatin organization|inhibition of heterochromatin organization|negative regulation of heterochromatin organization|down-regulation of heterochromatin organization	https://github.com/geneontology/go-ontology/issues/20020					krc	2020-09-29T20:12:30Z						biological_process											owl:Class	
GO:1904045	biolink:NamedThing	cellular response to aldosterone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.	got7fsn_ti							sl	2015-03-16T23:07:59Z						biological_process											owl:Class	
GO:1904504	biolink:NamedThing	positive regulation of lipophagy	Any process that activates or increases the frequency, rate or extent of lipophagy.	got7fsn_ti	up regulation of lipophagy|upregulation of lipophagy|activation of lipophagy|up-regulation of lipophagy						dph	2015-07-24T11:37:24Z						biological_process											owl:Class	
GO:1900434	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to starvation	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.	got7fsn_ti							di	2012-04-25T05:54:46Z						biological_process											owl:Class	
GO:0016088	biolink:NamedThing	obsolete insulin	OBSOLETE. A polypeptide hormone that stimulates glucose uptake by muscle and adipose tissue, and promotes glycogenesis, lipogenesis and the synthesis of proteins and nucleic acids.	got7fsn_ti	insulin				This term was made obsolete because it represents a gene product.	GO:0045935|GO:0046326|GO:0005102|GO:0046889|GO:0045722|GO:0045727				True				molecular_function											owl:Class	
GO:0046482	biolink:NamedThing	para-aminobenzoic acid metabolic process	The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.	got7fsn_ti	4-aminobenzoic acid metabolic process|vitamin Bx metabolism|PABA metabolic process|PABA metabolism|4-aminobenzoic acid metabolism|vitamin Bx metabolic process|p-aminobenzoic acid metabolism|para-aminobenzoic acid metabolism|p-aminobenzoic acid metabolic process													biological_process											owl:Class	
GO:0006183	biolink:NamedThing	GTP biosynthetic process	The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate.	got7fsn_ti	GTP anabolism|GTP synthesis|GTP formation|GTP biosynthesis													biological_process											owl:Class	
GO:0035303	biolink:NamedThing	regulation of dephosphorylation	Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.	got7fsn_ti														biological_process											owl:Class	
GO:1905260	biolink:NamedThing	positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.	got7fsn_ti	upregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up regulation of nitrosative stress-induced apoptosis|up-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|activation of intrinsic apoptotic signaling pathway in response to nitrosative stress|activation of nitrosative stress-induced intrinsic apoptotic signaling pathway|upregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|up-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|upregulation of nitrosative stress-induced apoptosis|activation of nitrosative stress-induced apoptosis|positive regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|up regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|positive regulation of nitrosative stress-induced apoptosis|up-regulation of nitrosative stress-induced apoptosis						bf	2016-06-13T17:05:15Z						biological_process											owl:Class	
GO:0051847	biolink:NamedThing	obsolete active evasion of symbiont immune response via regulation of symbiont complement system	OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, symbiont macrophages, which are eventually destroyed. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	active immune evasion via regulation of symbiont complement system|active immune evasion via modulation of symbiont complement system|active evasion of symbiont immune response via regulation of symbiont complement system				This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
GO:1904893	biolink:NamedThing	negative regulation of receptor signaling pathway via STAT	Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT.	got7fsn_ti	negative regulation of STAT signalling pathway|negative regulation of kinase-STAT cascade|down-regulation of STAT cascade|inhibition of STAT cascade|down regulation of kinase activated-STAT cascade|downregulation of kinase-STAT cascade|down-regulation of kinase-STAT cascade|inhibition of kinase-STAT cascade|downregulation of kinase activated-STAT cascade|down regulation of kinase-STAT cascade|down regulation of STAT signalling pathway|negative regulation of kinase activated-STAT cascade|down regulation of STAT cascade|inhibition of STAT signalling pathway|downregulation of STAT cascade|down-regulation of STAT signalling pathway|down-regulation of kinase activated-STAT cascade|inhibition of kinase activated-STAT cascade|downregulation of STAT signalling pathway						pr	2016-01-08T08:14:41Z						biological_process											owl:Class	
GO:0032681	biolink:NamedThing	regulation of lymphotoxin A production	Any process that modulates the frequency, rate, or extent of lymphotoxin A production.	got7fsn_ti	regulation of tumor necrosis factor-beta production|regulation of LTA production|regulation of lymphotoxin-alpha production|regulation of lymphotoxin A biosynthetic process|regulation of TNF-beta production										GO:0043016			biological_process											owl:Class	
GO:1901664	biolink:NamedThing	regulation of NAD+ ADP-ribosyltransferase activity	Any process that modulates the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.	got7fsn_ti	regulation of poly(ADP-ribose) synthetase activity|regulation of NAD ADP-ribosyltransferase activity|regulation of ADP-ribosyltransferase (polymerizing) activity|regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|regulation of poly(ADP-ribose)polymerase activity|regulation of poly(adenosine diphosphate ribose) polymerase activity|regulation of poly(ADP-ribose) synthase activity						vk	2012-11-20T18:50:07Z						biological_process											owl:Class	
GO:1905575	biolink:NamedThing	ganglioside GM3 binding	Binding to ganglioside GM3.	got7fsn_ti							pga	2016-10-19T11:17:10Z						molecular_function											owl:Class	
GO:0090322	biolink:NamedThing	regulation of superoxide metabolic process	Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.	got7fsn_ti	regulation of superoxide metabolism						tb	2010-05-06T02:29:05Z						biological_process											owl:Class	
GO:0036125	biolink:NamedThing	fatty acid beta-oxidation multienzyme complex	A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT).	got7fsn_ti					For fatty acid beta-oxidation multienzyme complexes located in the mitochondrial matrix, consider instead the term 'mitochondrial fatty acid beta-oxidation multienzyme complex ; GO:0016507'.		bf	2012-02-28T02:10:39Z						cellular_component											owl:Class	
GO:0001020	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009138	biolink:NamedThing	pyrimidine nucleoside diphosphate metabolic process	The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0000201	biolink:NamedThing	obsolete MAPK import into nucleus involved in cell wall organization or biogenesis	OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of cell wall organization or biogenesis.	got7fsn_ti	nuclear translocation of MAPK involved in cell wall biogenesis|cell wall biogenesis, MAPK import into nucleus|MAPK import into nucleus involved in cell wall integrity|MAPK import into nucleus involved in cell wall biogenesis|nuclear translocation of MAPK involved in cell wall integrity|cell wall biogenesis, nuclear translocation of MAPK				The reason for obsoletion is that this term represents a GO-CAM model.	GO:0006606				True				biological_process											owl:Class	
GO:0072125	biolink:NamedThing	negative regulation of glomerular mesangial cell proliferation	Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.	got7fsn_ti							mah	2010-02-22T01:48:49Z						biological_process											owl:Class	
GO:0034624	biolink:NamedThing	obsolete DNA recombinase assembly involved in gene conversion at mating-type locus	OBSOLETE. The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19999			This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1902912	biolink:NamedThing	pyruvate kinase complex	A protein complex which is capable of pyruvate kinase activity.	got7fsn_ti					An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).		bhm	2014-04-17T14:11:41Z						cellular_component											owl:Class	
GO:1905536	biolink:NamedThing	negative regulation of eukaryotic translation initiation factor 4F complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.	got7fsn_ti	downregulation of eukaryotic translation initiation factor 4F complex assembly|inhibition of eIF-4F assembly|downregulation of eIF-4F assembly|down-regulation of eIF4F assembly|negative regulation of eIF4F assembly|down-regulation of eukaryotic translation initiation factor 4F complex assembly|down regulation of eIF4F assembly|down-regulation of eIF-4F assembly|down regulation of eukaryotic translation initiation factor 4F complex assembly|down regulation of eIF-4F assembly|downregulation of eIF4F assembly|inhibition of eIF4F assembly|negative regulation of eIF-4F assembly|inhibition of eukaryotic translation initiation factor 4F complex assembly						bc	2016-10-06T14:05:06Z						biological_process											owl:Class	
GO:0004384	biolink:NamedThing	obsolete membrane-associated guanylate kinase	OBSOLETE. Catalysis of the reaction: ATP + GMP = ADP + GDP, associated with the cell membrane.	got7fsn_ti	membrane-associated guanylate kinase|MAGUK				This term was made obsolete because it represents a gene product and not a function.	GO:0005102|GO:0016021|GO:0004385|GO:0050839|GO:0007155				True				molecular_function											owl:Class	
GO:2001275	biolink:NamedThing	obsolete positive regulation of glucose import in response to insulin stimulus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus.	got7fsn_ti	positive regulation of cellular glucose import in response to insulin stimulus	https://github.com/geneontology/go-ontology/issues/15961			This term was obsoleted because it represents a GO-CAM model.		vk	2011-12-13T12:29:43Z		True				biological_process											owl:Class	
GO:1900939	biolink:NamedThing	negative regulation of (Z)-nonadeca-1,14-diene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.	got7fsn_ti	negative regulation of (Z)-nonadeca-1,14-diene metabolism|down regulation of (Z)-nonadeca-1,14-diene metabolism|down-regulation of (Z)-nonadeca-1,14-diene metabolism|downregulation of (Z)-nonadeca-1,14-diene metabolic process|down-regulation of (Z)-nonadeca-1,14-diene metabolic process|inhibition of (Z)-nonadeca-1,14-diene metabolism|downregulation of (Z)-nonadeca-1,14-diene metabolism|inhibition of (Z)-nonadeca-1,14-diene metabolic process|down regulation of (Z)-nonadeca-1,14-diene metabolic process						tt	2012-06-14T03:15:58Z						biological_process											owl:Class	
GO:1900398	biolink:NamedThing	negative regulation of pyrimidine nucleotide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.	got7fsn_ti	negative regulation of pyrimidine nucleotide anabolism|inhibition of pyrimidine nucleotide synthesis|down-regulation of pyrimidine nucleotide synthesis|inhibition of pyrimidine nucleotide anabolism|downregulation of pyrimidine nucleotide formation|down-regulation of pyrimidine nucleotide anabolism|negative regulation of pyrimidine nucleotide synthesis|down regulation of pyrimidine nucleotide biosynthetic process|negative regulation of pyrimidine nucleotide formation|down regulation of pyrimidine nucleotide biosynthesis|down-regulation of pyrimidine nucleotide formation|negative regulation of pyrimidine nucleotide biosynthesis|downregulation of pyrimidine nucleotide anabolism|down regulation of pyrimidine nucleotide formation|down-regulation of pyrimidine nucleotide biosynthesis|downregulation of pyrimidine nucleotide biosynthetic process|inhibition of pyrimidine nucleotide biosynthesis|down regulation of pyrimidine nucleotide anabolism|down regulation of pyrimidine nucleotide synthesis|down-regulation of pyrimidine nucleotide biosynthetic process|downregulation of pyrimidine nucleotide synthesis|inhibition of pyrimidine nucleotide formation|inhibition of pyrimidine nucleotide biosynthetic process|downregulation of pyrimidine nucleotide biosynthesis						jh	2012-04-19T01:05:41Z						biological_process											owl:Class	
GO:1903246	biolink:NamedThing	obsolete negative regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.	got7fsn_ti	inhibition of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of If activation by beta-adrenergic receptor signaling pathway|negative regulation of If activation by beta-adrenergic receptor signaling pathway|down-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|inhibition of activation of funny current by beta-adrenergic receptor signaling pathway|down regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|downregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of If activation by beta-adrenergic receptor signaling pathway|down regulation of If activation by beta-adrenergic receptor signaling pathway|negative regulation of activation of funny current by beta-adrenergic receptor signaling pathway|down-regulation of activation of funny current by beta-adrenergic receptor signaling pathway|inhibition of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|downregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|downregulation of If activation by beta-adrenergic receptor signaling pathway|inhibition of adrenergic receptor signalling pathway involved in positive regulation of heart rate|downregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|down-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of activation of funny current by beta-adrenergic receptor signaling pathway|downregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|negative regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|inhibition of adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of activation of funny current by beta-adrenergic receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/14733			This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		rl	2014-08-04T11:54:00Z		True				biological_process											owl:Class	
GO:0150013	biolink:NamedThing	negative regulation of neuron projection arborization	Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.	got7fsn_ti	negative regulation of neuron projection branching|negative regulation of neurite branching|negative regulation of neurite arborization						bc	2017-12-13T16:50:53Z						biological_process											owl:Class	
GO:0003789	biolink:NamedThing	obsolete actin filament severing activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	actin filament severing activity			GO:0051014	This term was made obsolete because it describes a biological process.					True				molecular_function											owl:Class	
GO:0140531	biolink:NamedThing	regulation of osmosensory signaling MAPK cascade	Any process that modulates the frequency, rate or extent of osmosensory signaling MAPK cascade.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20162					pg	2020-10-20T15:38:10Z						biological_process											owl:Class	
GO:1901579	biolink:NamedThing	positive regulation of alkane biosynthetic process	Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process.	got7fsn_ti	up regulation of alkane biosynthesis|up regulation of alkane formation|up-regulation of alkane formation|positive regulation of alkane biosynthesis|up-regulation of alkane anabolism|activation of alkane synthesis|positive regulation of alkane anabolism|activation of alkane formation|positive regulation of alkane synthesis|up-regulation of alkane synthesis|activation of alkane anabolism|up regulation of alkane anabolism|upregulation of alkane anabolism|upregulation of alkane biosynthesis|up regulation of alkane biosynthetic process|up-regulation of alkane biosynthesis|upregulation of alkane biosynthetic process|positive regulation of alkane formation|activation of alkane biosynthetic process|activation of alkane biosynthesis|upregulation of alkane synthesis|upregulation of alkane formation|up regulation of alkane synthesis|up-regulation of alkane biosynthetic process						dhl	2012-11-05T21:54:19Z						biological_process											owl:Class	
GO:1903922	biolink:NamedThing	negative regulation of protein processing in phagocytic vesicle	Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle.	got7fsn_ti	inhibition of protein maturation by peptide bond cleavage in phagosome|down-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|inhibition of protein maturation by peptide bond cleavage in phagocytic vesicle|inhibition of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down-regulation of protein processing in phagosome|negative regulation of protein processing in phagosome|downregulation of protein processing in phagosome|down regulation of protein maturation by proteolysis in phagocytic vesicle|negative regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|down-regulation of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein processing in phagocytic vesicle|inhibition of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein maturation by peptide bond hydrolysis in phagosome|negative regulation of protein maturation by proteolysis in phagosome|down-regulation of protein maturation by proteolysis in phagosome|downregulation of protein maturation by peptide bond cleavage in phagosome|down regulation of peptidolysis during protein maturation in phagosome|negative regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|down-regulation of protein maturation by peptide bond hydrolysis in phagosome|downregulation of protein processing in phagocytic vesicle|down regulation of protein processing in phagocytic vesicle|downregulation of protein maturation by proteolysis in phagosome|down-regulation of protein maturation by peptide bond cleavage in phagosome|downregulation of protein maturation by proteolysis in phagocytic vesicle|negative regulation of protein maturation by proteolysis in phagocytic vesicle|down-regulation of protein maturation by proteolysis in phagocytic vesicle|down-regulation of peptidolysis during protein maturation in phagosome|down regulation of protein maturation by peptide bond cleavage in phagosome|down-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down regulation of protein processing in phagosome|down regulation of protein maturation by peptide bond hydrolysis in phagosome|downregulation of protein maturation by peptide bond hydrolysis in phagosome|downregulation of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein maturation by proteolysis in phagocytic vesicle|down regulation of protein maturation by proteolysis in phagosome|down regulation of peptidolysis during protein maturation in phagocytic vesicle|negative regulation of peptidolysis during protein maturation in phagosome|negative regulation of protein maturation by peptide bond hydrolysis in phagosome|down regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|negative regulation of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein processing in phagosome|negative regulation of protein maturation by peptide bond cleavage in phagosome|downregulation of protein maturation by peptide bond cleavage in phagocytic vesicle|downregulation of peptidolysis during protein maturation in phagosome|inhibition of protein maturation by proteolysis in phagosome|down-regulation of protein processing in phagocytic vesicle|downregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|inhibition of peptidolysis during protein maturation in phagosome						als	2015-02-10T11:17:05Z						biological_process											owl:Class	
GO:0008511	biolink:NamedThing	sodium:potassium:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in).	got7fsn_ti	sodium/potassium/chloride symporter activity											Reactome:R-HSA-426086|Reactome:R-HSA-5623588		molecular_function											owl:Class	
GO:0051456	biolink:NamedThing	attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.	got7fsn_ti	meiotic bipolar attachment|attachment of spindle microtubules to kinetochore during meiosis II|attachment of spindle microtubules to kinetochore involved in meiosis II													biological_process											owl:Class	
GO:0052560	biolink:NamedThing	obsolete induction by organism of symbiont immune response	OBSOLETE. Any process by which an organism activates the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of symbiont immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1901464	biolink:NamedThing	negative regulation of tetrapyrrole biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process.	got7fsn_ti	down-regulation of tetrapyrrole biosynthetic process|downregulation of tetrapyrrole formation|downregulation of tetrapyrrole biosynthetic process|down regulation of tetrapyrrole formation|downregulation of tetrapyrrole anabolism|negative regulation of tetrapyrrole formation|down-regulation of tetrapyrrole anabolism|down regulation of tetrapyrrole synthesis|down-regulation of tetrapyrrole synthesis|inhibition of tetrapyrrole synthesis|downregulation of tetrapyrrole synthesis|downregulation of tetrapyrrole biosynthesis|inhibition of tetrapyrrole biosynthesis|inhibition of tetrapyrrole anabolism|down-regulation of tetrapyrrole formation|inhibition of tetrapyrrole biosynthetic process|down-regulation of tetrapyrrole biosynthesis|negative regulation of tetrapyrrole anabolism|negative regulation of tetrapyrrole synthesis|negative regulation of tetrapyrrole biosynthesis|down regulation of tetrapyrrole anabolism|inhibition of tetrapyrrole formation|down regulation of tetrapyrrole biosynthetic process|down regulation of tetrapyrrole biosynthesis						tt	2012-10-02T14:35:26Z						biological_process											owl:Class	
GO:2000110	biolink:NamedThing	negative regulation of macrophage apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.	got7fsn_ti	negative regulation of macrophage apoptosis|negative regulation of activation-induced cell death|negative regulation of AICD						mah	2010-09-15T01:44:18Z						biological_process											owl:Class	
GO:0042031	biolink:NamedThing	obsolete angiotensin-converting enzyme inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of angiotensin-converting enzyme, thereby preventing the synthesis of angiotensin II from its precursor, angiotensin I.	got7fsn_ti	ACE inhibitor|angiotensin-converting enzyme inhibitor activity|peptidyl dipeptidase A inhibitor			GO:0060422	This term was made obsolete because it represents a regulator of a non-existent molecular function term.					True				molecular_function											owl:Class	
GO:0051346	biolink:NamedThing	negative regulation of hydrolase activity	Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.	got7fsn_ti	hydrolase inhibitor|down-regulation of hydrolase activity|down regulation of hydrolase activity|inhibition of hydrolase activity|downregulation of hydrolase activity													biological_process											owl:Class	
GO:0001930	biolink:NamedThing	positive regulation of exocyst assembly	Any process that increases the rate or extent of exocyst assembly.	got7fsn_ti	activation of exocyst assembly|up-regulation of exocyst assembly|upregulation of exocyst assembly|stimulation of exocyst assembly|up regulation of exocyst assembly													biological_process											owl:Class	
GO:1901555	biolink:NamedThing	response to paclitaxel	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus.	got7fsn_ti							hp	2012-11-02T09:46:08Z						biological_process											owl:Class	
GO:1900410	biolink:NamedThing	obsolete regulation of histone modification by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone modification.	got7fsn_ti					This term was obsoleted because it describes a process that does not exist.		mah	2012-04-20T03:35:08Z		True				biological_process											owl:Class	
GO:0140279	biolink:NamedThing	regulation of mitotic division septum assembly	Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	got7fsn_ti	regulation of septin assembly and septum formation involved in mitotic cell cycle|regulation of division septum formation involved in mitotic cell cycle|regulation of formation of division septum involved in mitotic cell cycle|regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle						pg	2018-10-08T09:55:51Z						biological_process											owl:Class	
GO:0007194	biolink:NamedThing	negative regulation of adenylate cyclase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.	got7fsn_ti	down-regulation of adenylate cyclase activity|downregulation of adenylate cyclase activity|down regulation of adenylate cyclase activity|inhibition of adenylate cyclase activity|negative regulation of adenylyl cyclase activity|adenylate cyclase inhibitor													biological_process											owl:Class	
GO:1901380	biolink:NamedThing	negative regulation of potassium ion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.	got7fsn_ti	negative regulation of potassium ion membrane transport|down-regulation of potassium ion transmembrane transport|down regulation of potassium ion transmembrane transport|downregulation of potassium ion transmembrane transport|inhibition of potassium ion transmembrane transport						rl	2012-09-28T15:59:08Z						biological_process											owl:Class	
GO:0090528	biolink:NamedThing	smooth septate junction assembly	The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.	got7fsn_ti							tb	2013-02-05T14:47:40Z						biological_process											owl:Class	
GO:1905719	biolink:NamedThing	protein localization to perinuclear region of cytoplasm	A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm.	got7fsn_ti	protein localisation to perinuclear region of cytoplasm|protein localisation in perinuclear region of cytoplasm|protein localization in perinuclear region of cytoplasm|protein localization to perinuclear cytoplasm						mah	2016-11-24T16:51:55Z						biological_process											owl:Class	
GO:0000196	biolink:NamedThing	cell wall integrity MAPK cascade	A MAPK cascade that contributes to cell wall organization or biogenesis.	got7fsn_ti	Pmk1 MAPK cell integrity signaling|PMK1-MAPK signal transduction pathway|cell wall biogenesis, MAPKKK cascade|Slt2 cascade|cell integrity MAPK pathway|MAPK cascade involved in cell wall organization or biogenesis|Mpk1 cascade|MAPKKK cascade involved in cell wall biogenesis|Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|MAPK cascade involved in cell wall biogenesis													biological_process											owl:Class	
GO:0033861	biolink:NamedThing	negative regulation of NAD(P)H oxidase activity	Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.	got7fsn_ti	down-regulation of NAD(P)H oxidase activity|downregulation of NAD(P)H oxidase activity|down regulation of NAD(P)H oxidase activity|inhibition of NAD(P)H oxidase activity													biological_process											owl:Class	
GO:0002055	biolink:NamedThing	adenine binding	Binding to adenine, a purine base.	got7fsn_ti	6-aminopurine binding													molecular_function											owl:Class	
GO:0004624	biolink:NamedThing	obsolete secreted phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	got7fsn_ti	secreted phospholipase A2 activity				This term was made obsolete because it represents component and function information.	GO:0004623|GO:0005576				True				molecular_function											owl:Class	
GO:0009119	biolink:NamedThing	ribonucleoside metabolic process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	ribonucleoside metabolism													biological_process											owl:Class	
GO:1900758	biolink:NamedThing	negative regulation of D-amino-acid oxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity.	got7fsn_ti	inhibition of D-amino-acid oxidase activity|inhibition of L-amino acid:O2 oxidoreductase activity|downregulation of D-amino-acid oxidase activity|negative regulation of new yellow enzyme|down regulation of L-amino acid:O2 oxidoreductase activity|negative regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|down regulation of D-amino-acid oxidase activity|downregulation of new yellow enzyme|downregulation of L-amino acid:O2 oxidoreductase activity|down regulation of new yellow enzyme|down regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|down-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|negative regulation of L-amino acid:O2 oxidoreductase activity|inhibition of D-amino-acid:oxygen oxidoreductase (deaminating)|down-regulation of D-amino-acid oxidase activity|downregulation of D-amino-acid:oxygen oxidoreductase (deaminating)|down-regulation of L-amino acid:O2 oxidoreductase activity|down-regulation of new yellow enzyme|inhibition of new yellow enzyme						pm	2012-05-31T11:24:06Z						biological_process											owl:Class	
GO:0060727	biolink:NamedThing	positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.	got7fsn_ti	positive regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway|positive regulation of Neu/ErbB-2 receptor activity						dph	2009-06-12T01:30:50Z						biological_process											owl:Class	
GO:0019268	biolink:NamedThing	obsolete glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)	OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate dehydrogenase (NADP+).	got7fsn_ti	glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamate anabolism, using glutamate dehydrogenase (NAD(P)+)|glutamate synthesis, using glutamate dehydrogenase (NAD(P)+)|glutamate formation, using glutamate dehydrogenase (NAD(P)+)				This term was made obsolete because it represents a molecular function.	GO:0004353|GO:0006537				True				biological_process											owl:Class	
GO:0009471	biolink:NamedThing	obsolete class III cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	class III cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0071851	biolink:NamedThing	obsolete mitotic G1 cell cycle arrest in response to nitrogen starvation	OBSOLETE. The process in which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.	got7fsn_ti	G1 mitotic cell cycle arrest in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/20989			This term was obsoleted because it does not represent a specific process.		mah	2010-09-10T02:58:09Z		True				biological_process											owl:Class	
GO:1901241	biolink:NamedThing	4-hydroxyphenylacetate transmembrane transporter activity	Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other.	got7fsn_ti							jl	2012-08-07T15:09:49Z				RHEA:33175		molecular_function											owl:Class	
CHEBI:58389	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904501	biolink:NamedThing	obsolete positive regulation of chromatin-mediated maintenance of transcription	OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin-mediated maintenance of transcription.	got7fsn_ti	up-regulation of chromatin-mediated maintenance of transcription|upregulation of chromatin-mediated maintenance of transcription|up regulation of chromatin-mediated maintenance of transcription|activation of chromatin-mediated maintenance of transcription				This term was obsoleted because it represents a readout.		nc	2015-07-24T09:31:20Z		True				biological_process											owl:Class	
GO:0030602	biolink:NamedThing	obsolete chymosin activity	OBSOLETE. Catalysis of the lysis of peptide bonds with broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe-l-Met-Ala bond in kappa-casein.	got7fsn_ti	chymosin activity|rennin (but this should be avoided since it leads to confusion with renin)|rennin			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0034410	biolink:NamedThing	cell wall beta-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.	got7fsn_ti	cell wall beta-glucan anabolism|cell wall beta-glucan synthesis|cell wall beta-glucan biosynthesis|cell wall beta-glucan formation													biological_process											owl:Class	
GO:0052317	biolink:NamedThing	camalexin metabolic process	The chemical reactions and pathways involving camalexin, an indole phytoalexin.	got7fsn_ti	camalexin metabolism													biological_process											owl:Class	
OBO:OBA_0000139	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900085	biolink:NamedThing	negative regulation of peptidyl-tyrosine autophosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.	got7fsn_ti	down regulation of tyrosine autophosphorylation|negative regulation of receptor tyrosine kinase autophosphorylation|inhibition of peptidyl-tyrosine autophosphorylation|down-regulation of peptidyl-tyrosine autophosphorylation|down regulation of peptidyl-tyrosine autophosphorylation|down regulation of receptor tyrosine kinase autophosphorylation|downregulation of peptidyl-tyrosine autophosphorylation|down-regulation of tyrosine autophosphorylation|inhibition of tyrosine autophosphorylation|downregulation of receptor tyrosine kinase autophosphorylation|negative regulation of tyrosine autophosphorylation|down-regulation of receptor tyrosine kinase autophosphorylation|inhibition of receptor tyrosine kinase autophosphorylation|downregulation of tyrosine autophosphorylation						bf	2012-02-03T10:17:12Z						biological_process											owl:Class	
GO:1903325	biolink:NamedThing	positive regulation of snoRNA metabolic process	Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process.	got7fsn_ti	up-regulation of snoRNA metabolic process|up regulation of snoRNA metabolism|activation of snoRNA metabolism|upregulation of snoRNA metabolic process|activation of snoRNA metabolic process|up regulation of snoRNA metabolic process|positive regulation of snoRNA metabolism|upregulation of snoRNA metabolism|up-regulation of snoRNA metabolism						vw	2014-08-18T13:05:33Z						biological_process											owl:Class	
GO:1904661	biolink:NamedThing	negative regulation of sensory perception of bitter taste	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste.	got7fsn_ti	inhibition of sensory perception of bitter taste|inhibition of bitter taste perception|down regulation of bitter taste perception|negative regulation of bitter taste perception|down regulation of sensory perception of bitter taste|down-regulation of bitter taste perception|down-regulation of sensory perception of bitter taste|downregulation of sensory perception of bitter taste|downregulation of bitter taste perception						mr	2015-09-04T17:54:17Z						biological_process											owl:Class	
GO:2000229	biolink:NamedThing	regulation of pancreatic stellate cell proliferation	Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation.	got7fsn_ti							mah	2010-11-09T03:45:18Z						biological_process											owl:Class	
GO:0034776	biolink:NamedThing	response to histamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.	got7fsn_ti	response to histamine stimulus													biological_process											owl:Class	
GO:0000189	biolink:NamedThing	obsolete MAPK import into nucleus	OBSOLETE. The directed movement of a MAP kinase to the nucleus upon activation.	got7fsn_ti	nuclear translocation of MAPK				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606				True				biological_process											owl:Class	
GO:1904387	biolink:NamedThing	cellular response to L-phenylalanine derivative	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.	got7fsn_ti							sl	2015-06-23T17:56:25Z						biological_process											owl:Class	
GO:0031378	biolink:NamedThing	obsolete plastid type II fatty acid synthase complex	OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in a plastid.	got7fsn_ti	plastid type II FAS complex|plastid type II fatty acid synthase complex				Obsoleted because type II fatty acid synthase is not a complex.					True				cellular_component											owl:Class	
GO:0062174	biolink:NamedThing	brexanolone biosynthetic process	The chemical reactions and pathways resulting in the formation of brexanolone.	got7fsn_ti	allotetrahydroprogesterone synthesis|allotetrahydroprogesterone biosynthetic process|allopregnanolone biosynthesis|brexanolone synthesis|allopregnanolone anabolism|allotetrahydroprogesterone anabolism|allopregnanolone biosynthetic process|allotetrahydroprogesterone biosynthesis|brexanolone anabolism|brexanolone biosynthesis|allopregnanolone synthesis						dph	2019-11-18T19:48:14Z						biological_process											owl:Class	
GO:0035787	biolink:NamedThing	cell migration involved in kidney development	The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.	got7fsn_ti							bf	2011-04-06T10:39:52Z						biological_process											owl:Class	
GO:0048191	biolink:NamedThing	obsolete peptide stabilization activity	OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.	got7fsn_ti	peptide stabilization activity			GO:0050822	This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:0032805	biolink:NamedThing	positive regulation of low-density lipoprotein particle receptor catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.	got7fsn_ti	positive regulation of low-density lipoprotein receptor breakdown|positive regulation of low-density lipoprotein receptor degradation|positive regulation of low-density lipoprotein receptor catabolism|up-regulation of low-density lipoprotein receptor catabolic process|up regulation of low-density lipoprotein receptor catabolic process|positive regulation of low-density lipoprotein receptor catabolic process|upregulation of low-density lipoprotein receptor catabolic process|activation of low-density lipoprotein receptor catabolic process|stimulation of low-density lipoprotein receptor catabolic process													biological_process											owl:Class	
GO:1905152	biolink:NamedThing	positive regulation of voltage-gated sodium channel activity	Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity.	got7fsn_ti	positive regulation of voltage-sensitive sodium channel|up-regulation of voltage-gated sodium ion channel activity|up-regulation of voltage gated sodium channel activity|activation of voltage-sensitive sodium channel|upregulation of voltage-sensitive sodium channel|upregulation of voltage gated sodium channel activity|up regulation of voltage-gated sodium ion channel activity|up regulation of voltage-dependent sodium channel activity|up regulation of voltage gated sodium channel activity|activation of voltage-gated sodium channel activity|upregulation of voltage-gated sodium ion channel activity|up regulation of voltage-sensitive sodium channel|positive regulation of voltage-gated sodium ion channel activity|upregulation of voltage-gated sodium channel activity|positive regulation of voltage gated sodium channel activity|activation of voltage gated sodium channel activity|up regulation of voltage-gated sodium channel activity|up-regulation of voltage-dependent sodium channel activity|activation of voltage-gated sodium ion channel activity|up-regulation of voltage-gated sodium channel activity|upregulation of voltage-dependent sodium channel activity|activation of voltage-dependent sodium channel activity|positive regulation of voltage-dependent sodium channel activity|up-regulation of voltage-sensitive sodium channel						sl	2016-04-15T21:47:57Z						biological_process											owl:Class	
GO:0046262	biolink:NamedThing	obsolete nitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.	got7fsn_ti	nitrotoluene biosynthetic process|nitrotoluene synthesis|nitrotoluene formation|nitrotoluene biosynthesis|nitrotoluene anabolism			GO:0019326	This term was made obsolete because nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0010986	biolink:NamedThing	positive regulation of lipoprotein particle clearance	Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							tb	2009-06-01T12:08:19Z						biological_process											owl:Class	
GO:1901587	biolink:NamedThing	positive regulation of acid-sensing ion channel activity	Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity.	got7fsn_ti	up regulation of ASIC activity|upregulation of acid-sensing ion channel activity|up-regulation of acid-sensing ion channel activity|activation of acid-sensing ion channel activity|activation of ASIC activity|up regulation of acid-sensing ion channel activity|upregulation of ASIC activity|up-regulation of ASIC activity|positive regulation of ASIC activity						jl	2012-11-07T13:37:37Z						biological_process											owl:Class	
GO:0010652	biolink:NamedThing	positive regulation of cell communication by chemical coupling	Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti														biological_process											owl:Class	
GO:2000296	biolink:NamedThing	negative regulation of hydrogen peroxide catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process.	got7fsn_ti	negative regulation of hydrogen peroxide catabolism|negative regulation of detoxification of hydrogen peroxide|negative regulation of hydrogen peroxide scavenging|negative regulation of hydrogen peroxide removal|negative regulation of detoxification of H2O2|negative regulation of hydrogen peroxide breakdown|negative regulation of hydrogen peroxide degradation|negative regulation of H2O2 scavenging|negative regulation of H2O2 catabolic process						rl	2010-12-21T03:30:55Z						biological_process											owl:Class	
GO:0046182	biolink:NamedThing	L-idonate biosynthetic process	The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	got7fsn_ti	L-idonate formation|L-idonate synthesis|L-idonate biosynthesis|L-idonate anabolism													biological_process											owl:Class	
GO:1902443	biolink:NamedThing	negative regulation of ripoptosome assembly involved in necroptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.	got7fsn_ti	down-regulation of ripoptosome assembly involved in necroptosis|negative regulation of ripoptosome assembly involved in necroptosis|inhibition of ripoptosome assembly involved in necroptosis|downregulation of ripoptosome assembly involved in necroptosis|down regulation of ripoptosome assembly involved in necroptosis						dph	2013-10-10T17:51:41Z						biological_process											owl:Class	
GO:1903591	biolink:NamedThing	negative regulation of lysozyme activity	Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity.	got7fsn_ti	downregulation of N,O-diacetylmuramidase activity|down-regulation of muramidase activity|downregulation of lysozyme g|down-regulation of lysozyme activity|down-regulation of mucopeptide glucohydrolase activity|inhibition of muramidase activity|inhibition of 1,4-N-acetylmuramidase activity|inhibition of lysozyme activity|down regulation of mucopeptide glucohydrolase activity|downregulation of peptidoglycan N-acetylmuramoylhydrolase activity|inhibition of peptidoglycan N-acetylmuramoylhydrolase activity|inhibition of L-7001|negative regulation of globulin G1|down regulation of L-7001|down-regulation of globulin G1|down-regulation of peptidoglycan N-acetylmuramoylhydrolase activity|negative regulation of lysozyme g|down-regulation of L-7001|downregulation of mucopeptide N-acetylmuramoylhydrolase activity|down regulation of N,O-diacetylmuramidase activity|negative regulation of N,O-diacetylmuramidase activity|downregulation of globulin G|down regulation of peptidoglycan N-acetylmuramoylhydrolase activity|down-regulation of 1,4-N-acetylmuramidase activity|negative regulation of muramidase activity|inhibition of lysozyme g|inhibition of globulin G|downregulation of L-7001|negative regulation of mucopeptide N-acetylmuramoylhydrolase activity|downregulation of 1,4-N-acetylmuramidase activity|down regulation of lysozyme g|down-regulation of PR1-lysozyme|negative regulation of peptidoglycan N-acetylmuramoylhydrolase activity|inhibition of N,O-diacetylmuramidase activity|inhibition of mucopeptide glucohydrolase activity|negative regulation of mucopeptide glucohydrolase activity|down regulation of lysozyme activity|downregulation of muramidase activity|negative regulation of L-7001|down-regulation of N,O-diacetylmuramidase activity|downregulation of lysozyme activity|down regulation of globulin G|down-regulation of lysozyme g|down-regulation of mucopeptide N-acetylmuramoylhydrolase activity|downregulation of PR1-lysozyme|down-regulation of globulin G|down regulation of PR1-lysozyme|downregulation of globulin G1|down regulation of globulin G1|inhibition of globulin G1|down regulation of muramidase activity|inhibition of mucopeptide N-acetylmuramoylhydrolase activity|down regulation of 1,4-N-acetylmuramidase activity|down regulation of mucopeptide N-acetylmuramoylhydrolase activity|negative regulation of globulin G|inhibition of PR1-lysozyme|negative regulation of 1,4-N-acetylmuramidase activity|negative regulation of PR1-lysozyme|downregulation of mucopeptide glucohydrolase activity						mr	2014-11-05T21:41:30Z						biological_process											owl:Class	
GO:1905836	biolink:NamedThing	response to triterpenoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.	got7fsn_ti							sl	2017-01-17T19:37:36Z						biological_process											owl:Class	
GO:2000836	biolink:NamedThing	positive regulation of androgen secretion	Any process that activates or increases the frequency, rate or extent of androgen secretion.	got7fsn_ti							bf	2011-07-26T08:39:51Z						biological_process											owl:Class	
GO:0045562	biolink:NamedThing	obsolete regulation of TRAIL receptor 2 biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.	got7fsn_ti	regulation of TRAIL receptor 2 synthesis|regulation of TRAIL receptor 2 biosynthesis|regulation of TRAIL receptor 2 formation|regulation of TRAIL receptor 2 anabolism	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1901330	biolink:NamedThing	negative regulation of odontoblast differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation.	got7fsn_ti	down-regulation of odontoblast differentiation|downregulation of odontoblast differentiation|down regulation of odontoblast differentiation|inhibition of odontoblast differentiation						hjd	2012-08-31T16:50:27Z						biological_process											owl:Class	
GO:0010591	biolink:NamedThing	regulation of lamellipodium assembly	Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.	got7fsn_ti	regulation of lamellipodium biogenesis													biological_process											owl:Class	
GO:1904446	biolink:NamedThing	positive regulation of establishment of Sertoli cell barrier	Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier.	got7fsn_ti	activation of establishment of Sertoli cell barrier|up regulation of establishment of SCB|up-regulation of establishment of Sertoli cell barrier|up-regulation of establishment of SCB|up-regulation of establishment of blood-testis barrier|upregulation of establishment of Sertoli cell barrier|positive regulation of establishment of blood-testis barrier|positive regulation of establishment of BTB|upregulation of establishment of SCB|activation of establishment of blood-testis barrier|up regulation of establishment of blood-testis barrier|upregulation of establishment of BTB|up regulation of establishment of BTB|upregulation of establishment of blood-testis barrier|up-regulation of establishment of BTB|activation of establishment of SCB|activation of establishment of BTB|positive regulation of establishment of SCB|up regulation of establishment of Sertoli cell barrier						sl	2015-07-06T16:00:54Z						biological_process											owl:Class	
GO:0010550	biolink:NamedThing	regulation of PSII associated light-harvesting complex II catabolic process	Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.	got7fsn_ti	regulation of LHCII catabolism|regulation of LHCII degradation													biological_process											owl:Class	
GO:1905477	biolink:NamedThing	positive regulation of protein localization to membrane	Any process that activates or increases the frequency, rate or extent of protein localization to membrane.	got7fsn_ti	activation of protein localisation in membrane|up regulation of protein localization in membrane|up regulation of protein localisation in membrane|up-regulation of protein localisation in membrane|up regulation of protein localization to membrane|upregulation of protein localization to membrane|positive regulation of protein localization in membrane|up-regulation of protein localization to membrane|up-regulation of protein localization in membrane|upregulation of protein localization in membrane|positive regulation of protein localisation in membrane|upregulation of protein localisation in membrane|activation of protein localization in membrane|activation of protein localization to membrane						bc	2016-09-21T16:20:18Z						biological_process											owl:Class	
GO:1904955	biolink:NamedThing	planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation	Any Wnt signaling pathway, planar cell polarity pathway that is involved in midbrain dopaminergic neuron differentiation.	got7fsn_ti	non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway, planar cell polarity pathway involved in mDA neuron differentiation|Wnt-PCP signaling pathway involved in mDA neuron differentiation|Wnt-activated signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|PCP pathway involved in midbrain dopaminergic neuron production|planar cell polarity pathway involved in midbrain DA neurogenesis|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|PCP pathway involved in mDA neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|planar cell polarity pathway involved in midbrain dopaminergic neuron production|Wnt signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|Wnt-JNK signaling pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron differentiation|PCP pathway involved in midbrain dopaminergic neuron differentiation|PCP pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|PCP pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|Wnt signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt-JNK signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-PCP signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-PCP signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron production|planar cell polarity pathway involved in mDA neuron differentiation|Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt-mediated midbrain DA neuron differentiation|Wnt-JNK signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis|Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt signaling pathway involved in mDA neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production						bf	2016-02-09T11:04:56Z						biological_process											owl:Class	
GO:0006245	biolink:NamedThing	TDP catabolic process	The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate.	got7fsn_ti	TDP breakdown|TDP catabolism|TDP degradation													biological_process											owl:Class	
GO:0031408	biolink:NamedThing	oxylipin biosynthetic process	The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.	got7fsn_ti	oxylipin formation|oxylipin biosynthesis|oxylipin synthesis|oxylipin anabolism													biological_process											owl:Class	
GO:0019260	biolink:NamedThing	1,2-dichloroethane catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.	got7fsn_ti	1,2-dichloroethane breakdown|1,2-dichloroethane degradation|1,2-dichloroethane catabolism											MetaCyc:12DICHLORETHDEG-PWY		biological_process											owl:Class	
GO:1900888	biolink:NamedThing	negative regulation of pentadecane biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process.	got7fsn_ti	negative regulation of pentadecane formation|down regulation of pentadecane biosynthesis|inhibition of pentadecane biosynthesis|down-regulation of pentadecane biosynthesis|downregulation of pentadecane formation|downregulation of pentadecane biosynthetic process|downregulation of pentadecane anabolism|down regulation of pentadecane synthesis|down-regulation of pentadecane synthesis|down-regulation of pentadecane anabolism|inhibition of pentadecane formation|negative regulation of pentadecane anabolism|downregulation of pentadecane biosynthesis|inhibition of pentadecane biosynthetic process|downregulation of pentadecane synthesis|inhibition of pentadecane anabolism|negative regulation of pentadecane synthesis|down regulation of pentadecane formation|down-regulation of pentadecane formation|down-regulation of pentadecane biosynthetic process|down regulation of pentadecane anabolism|inhibition of pentadecane synthesis|down regulation of pentadecane biosynthetic process|negative regulation of pentadecane biosynthesis						tt	2012-06-13T03:03:57Z						biological_process											owl:Class	
GO:1904025	biolink:NamedThing	positive regulation of glucose catabolic process to lactate via pyruvate	Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.	got7fsn_ti	up-regulation of homofermentative pathway|up regulation of homolactic fermentation|activation of glucose catabolic process to lactate via pyruvate|upregulation of homofermentative pathway|upregulation of glucose catabolic process to lactate via pyruvate|up-regulation of glucose catabolic process to lactate via pyruvate|up regulation of homofermentation|up-regulation of homofermentative lactate fermentation|up-regulation of homolactate fermentation|activation of homofermentative lactate fermentation|up regulation of homolactate fermentation|upregulation of glucose fermentation to lactate via pyruvate|up-regulation of homolactic fermentation|up-regulation of glucose fermentation to lactate via pyruvate|up regulation of glucose catabolic process to lactate via pyruvate|positive regulation of homofermentative pathway|activation of homofermentative pathway|up-regulation of homofermentation|upregulation of homolactic fermentation|upregulation of homofermentation|activation of homolactate fermentation|upregulation of homolactate fermentation|positive regulation of glucose fermentation to lactate via pyruvate|activation of homofermentation|up regulation of homofermentative lactate fermentation|activation of homolactic fermentation|positive regulation of homofermentation|positive regulation of homofermentative lactate fermentation|up regulation of glucose fermentation to lactate via pyruvate|positive regulation of homolactate fermentation|positive regulation of homolactic fermentation|activation of glucose fermentation to lactate via pyruvate|upregulation of homofermentative lactate fermentation|up regulation of homofermentative pathway						dph	2015-03-11T16:57:44Z						biological_process											owl:Class	
GO:0033642	biolink:NamedThing	modulation by symbiont of host response to gravitational stimulus	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	response to gravitational stimulus													biological_process											owl:Class	
GO:0043862	biolink:NamedThing	arginine:agmatine antiporter activity	Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out).	got7fsn_ti	arginine-agmatine exchange transporter activity|arginine/agmatine antiporter activity|AdiC|arginine-agmatine antiporter activity													molecular_function											owl:Class	
GO:1900369	biolink:NamedThing	negative regulation of RNA interference	Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference.	got7fsn_ti	down regulation of posttranscriptional gene silencing by siRNA|down regulation of RNAi|down-regulation of RNAi|downregulation of RNA interference|down-regulation of RNA interference|down-regulation of posttranscriptional gene silencing by siRNA|down regulation of RNA interference|downregulation of posttranscriptional gene silencing by siRNA|inhibition of RNA interference|negative regulation of RNAi|downregulation of RNAi|inhibition of posttranscriptional gene silencing by siRNA|negative regulation of posttranscriptional gene silencing by siRNA|inhibition of RNAi						kmv	2012-04-13T08:28:50Z						biological_process											owl:Class	
GO:0035356	biolink:NamedThing	cellular triglyceride homeostasis	Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.	got7fsn_ti							bf	2010-03-05T10:28:11Z						biological_process											owl:Class	
GO:0085024	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by Sec complex	OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Sec complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by symbiont of host morphology or physiology via protein secreted by the Sec secretion system				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:44:31Z		True				biological_process											owl:Class	
GO:1905025	biolink:NamedThing	negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.	got7fsn_ti	inhibition of ventricular repolarization|negative regulation of ventricular repolarization|downregulation of electrocardiogram T wave|inhibition of electrocardiogram T wave|down regulation of regulation of ventricular cardiac muscle repolarization|inhibition of regulation of ventricular cardiac muscle repolarization|down regulation of ventricular repolarization|down-regulation of electrocardiogram T wave|down-regulation of ventricular repolarization|inhibition of membrane repolarization during ventricular cardiac muscle cell action potential|down-regulation of regulation of ventricular cardiac muscle repolarization|downregulation of membrane repolarization during ventricular cardiac muscle cell action potential|down regulation of membrane repolarization during ventricular cardiac muscle cell action potential|downregulation of ventricular repolarization|down regulation of electrocardiogram T wave|downregulation of regulation of ventricular cardiac muscle repolarization|down-regulation of membrane repolarization during ventricular cardiac muscle cell action potential|negative regulation of electrocardiogram T wave|negative regulation of regulation of ventricular cardiac muscle repolarization						rph	2016-03-04T11:19:12Z						biological_process											owl:Class	
GO:1904869	biolink:NamedThing	regulation of protein localization to Cajal body	Any process that modulates the frequency, rate or extent of protein localization to Cajal body.	got7fsn_ti	regulation of protein localization in Cajal body|regulation of protein localisation in Cajal body|regulation of protein localisation to Cajal body						nc	2015-12-18T11:17:31Z						biological_process											owl:Class	
GO:0006441	biolink:NamedThing	obsolete binding to mRNA cap	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	binding to mRNA cap				This term was made obsolete because it represents a function rather than a process.	GO:0000339				True				biological_process											owl:Class	
GO:1903672	biolink:NamedThing	positive regulation of sprouting angiogenesis	Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis.	got7fsn_ti	activation of sprouting angiogenesis|up regulation of sprouting angiogenesis|up-regulation of sprouting angiogenesis|upregulation of sprouting angiogenesis						pga	2014-11-27T10:11:08Z						biological_process											owl:Class	
PR:000005932	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019334	biolink:NamedThing	p-cymene catabolic process	The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.	got7fsn_ti	p-cymene breakdown|p-cymene degradation|p-cymene catabolism											MetaCyc:PWY-741		biological_process											owl:Class	
GO:1902430	biolink:NamedThing	negative regulation of amyloid-beta formation	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation.	got7fsn_ti	down-regulation of beta-amyloid formation|inhibition of beta-amyloid formation|negative regulation of beta-amyloid formation|down regulation of beta-amyloid formation|downregulation of beta-amyloid formation						hjd	2013-09-25T17:41:01Z						biological_process											owl:Class	
GO:0005081	biolink:NamedThing	obsolete receptor signaling protein serine/threonine phosphatase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	receptor signalling protein serine/threonine phosphatase signalling protein activity|receptor signaling protein serine/threonine phosphatase signaling protein activity				This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556				True				molecular_function											owl:Class	
GO:0060692	biolink:NamedThing	mesenchymal cell differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.	got7fsn_ti							dph	2009-06-08T01:08:44Z						biological_process											owl:Class	
OBO:OBA_0000052	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903501	biolink:NamedThing	positive regulation of mitotic actomyosin contractile ring assembly	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly.	got7fsn_ti	upregulation of mitotic actomyosin contractile ring assembly|upregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|up regulation of mitotic actomyosin contractile ring assembly|activation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up-regulation of mitotic actomyosin contractile ring assembly|up-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|activation of mitotic actomyosin contractile ring assembly|upregulation of contractile ring assembly involved in mitotic cytokinesis|upregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up regulation of contractile ring assembly involved in mitotic cytokinesis|up-regulation of contractile ring assembly involved in mitotic cytokinesis|positive regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|positive regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|activation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|up regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|positive regulation of contractile ring assembly involved in mitotic cytokinesis|up-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|activation of contractile ring assembly involved in mitotic cytokinesis|positive regulation of mitotic cytokinesis, actomyosin contractile ring assembly						pr	2014-09-30T10:14:07Z						biological_process											owl:Class	
GO:0010734	biolink:NamedThing	negative regulation of protein glutathionylation	Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.	got7fsn_ti	negative regulation of protein amino acid glutathionylation													biological_process											owl:Class	
GO:2000880	biolink:NamedThing	positive regulation of dipeptide transport	Any process that activates or increases the frequency, rate or extent of dipeptide transport.	got7fsn_ti							bf	2011-07-27T02:55:24Z						biological_process											owl:Class	
GO:1904329	biolink:NamedThing	negative regulation of myofibroblast contraction	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction.	got7fsn_ti	down-regulation of MFB contraction|down regulation of MF contraction|inhibition of myofibroblast contraction|inhibition of MFB contraction|negative regulation of MFB contraction|down regulation of myofibroblast contraction|downregulation of MF contraction|negative regulation of MF contraction|down-regulation of MF contraction|down regulation of MFB contraction|downregulation of myofibroblast contraction|inhibition of MF contraction|downregulation of MFB contraction|down-regulation of myofibroblast contraction						sl	2015-06-11T15:30:35Z						biological_process											owl:Class	
GO:2000923	biolink:NamedThing	positive regulation of arabinoxylan-containing compound catabolic process	Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process.	got7fsn_ti	positive regulation of arabinoxylan catabolism						tt	2011-08-01T12:39:02Z						biological_process											owl:Class	
GO:0030940	biolink:NamedThing	obsolete response to short-day photoperiod	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the dark phase being longer than the light.	got7fsn_ti	response to short-day photoperiod				This term was made obsolete because it was wrongly defined.	GO:0048572				True				biological_process											owl:Class	
GO:0046347	biolink:NamedThing	mannosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.	got7fsn_ti	mannosamine anabolism|mannosamine biosynthesis|mannosamine formation|mannosamine synthesis													biological_process											owl:Class	
GO:1901820	biolink:NamedThing	alpha-zeacarotene catabolic process	The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene.	got7fsn_ti	alpha-zeacarotene degradation|alpha-zeacarotene catabolism|alpha-zeacarotene breakdown						yaf	2013-01-22T10:51:06Z						biological_process											owl:Class	
GO:0061058	biolink:NamedThing	regulation of peptidoglycan recognition protein signaling pathway	Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.	got7fsn_ti	regulation of peptidoglycan recognition protein signalling pathway						dph	2010-03-02T12:35:40Z						biological_process											owl:Class	
GO:0099160	biolink:NamedThing	postsynaptic intermediate filament cytoskeleton	The intermediate filament cytoskeleton that is part of a postsynapse.	got7fsn_ti							dos	2017-08-28T15:26:08Z						cellular_component											owl:Class	
GO:0016086	biolink:NamedThing	obsolete allatostatin	OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone.	got7fsn_ti	allatostatin				This term was made obsolete because it refers to a gene product.	GO:0045968|GO:0005102				True				molecular_function											owl:Class	
GO:0005781	biolink:NamedThing	obsolete peroxisome targeting signal receptor complex	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peroxisome targeting signal receptor complex				This term was made obsolete because it represents a single polypeptide rather than a complex; all known peroxisome targeting signal receptors are monomeric.	GO:0006625|GO:0000268				True				cellular_component											owl:Class	
GO:1901312	biolink:NamedThing	obsolete negative regulation of gene expression involved in extracellular matrix organization	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of gene expression involved in extracellular matrix organization.	got7fsn_ti	downregulation of gene expression involved in extracellular matrix organization|down regulation of expression of extracellular matrix proteins|down-regulation of expression of extracellular matrix proteins|negative regulation of extracellular matrix protein production|downregulation of expression of extracellular matrix proteins|downregulation of extracellular matrix protein production|inhibition of extracellular matrix protein production|down regulation of gene expression involved in extracellular matrix organization|down regulation of extracellular matrix protein production|inhibition of gene expression involved in extracellular matrix organization|inhibition of expression of extracellular matrix proteins|negative regulation of expression of extracellular matrix proteins|down-regulation of extracellular matrix protein production|down-regulation of gene expression involved in extracellular matrix organization				This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization.	GO:0010629	vk	2012-08-22T09:18:35Z		True				biological_process											owl:Class	
GO:1904742	biolink:NamedThing	regulation of telomeric DNA binding	Any process that modulates the frequency, rate or extent of telomeric DNA binding.	got7fsn_ti	regulation of telomere binding|regulation of telomeric repeat binding						nc	2015-10-19T12:18:48Z						biological_process											owl:Class	
GO:0075310	biolink:NamedThing	regulation of sporangium development	Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.	got7fsn_ti														biological_process											owl:Class	
GO:0045338	biolink:NamedThing	farnesyl diphosphate metabolic process	The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.	got7fsn_ti	farnesyl diphosphate metabolism													biological_process											owl:Class	
GO:1903180	biolink:NamedThing	negative regulation of dopamine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process.	got7fsn_ti	down-regulation of dopamine formation|inhibition of dopamine anabolism|inhibition of dopamine formation|down regulation of dopamine biosynthetic process|downregulation of dopamine synthesis|inhibition of dopamine biosynthetic process|down regulation of dopamine biosynthesis|down-regulation of dopamine biosynthesis|negative regulation of dopamine formation|downregulation of dopamine formation|negative regulation of dopamine synthesis|down-regulation of dopamine synthesis|downregulation of dopamine biosynthesis|down regulation of dopamine synthesis|inhibition of dopamine synthesis|down-regulation of dopamine anabolism|down regulation of dopamine formation|negative regulation of dopamine anabolism|downregulation of dopamine biosynthetic process|downregulation of dopamine anabolism|down-regulation of dopamine biosynthetic process|down regulation of dopamine anabolism|inhibition of dopamine biosynthesis|negative regulation of dopamine biosynthesis						bf	2014-07-14T12:17:47Z						biological_process											owl:Class	
GO:0048192	biolink:NamedThing	obsolete peptide antigen stabilization activity	OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell.	got7fsn_ti	peptide antigen stabilization activity			GO:0050823	This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:1900751	biolink:NamedThing	4-(trimethylammonio)butanoate transport	The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	gamma-butyrobetaine transport|4-(N-trimethylamino)butyrate transport|gamma-Butyrobetain transport|C7H15NO2 transport|4-butyrobetaine transport|deoxycarnitine transport|Actinine transport|butyrobetaine transport						jl	2012-05-29T02:32:37Z						biological_process											owl:Class	
GO:0052326	biolink:NamedThing	obsolete interaction with symbiont via protein secreted by type IV secretion system	OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type IV secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with symbiont via protein secreted by type IV secretion system				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0034187	biolink:NamedThing	obsolete apolipoprotein E binding	OBSOLETE. Binding to apolipoprotein E.	got7fsn_ti	apolipoprotein E binding			GO:0034185	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:1901491	biolink:NamedThing	negative regulation of lymphangiogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis.	got7fsn_ti	down-regulation of lymph vessel formation|down regulation of lymphangiogenesis|down-regulation of lymphangiogenesis|downregulation of lymphangiogenesis|inhibition of lymphangiogenesis|negative regulation of lymph vessel formation|down regulation of lymph vessel formation|inhibition of lymph vessel formation|downregulation of lymph vessel formation						dph	2012-10-15T13:08:21Z						biological_process											owl:Class	
GO:1904135	biolink:NamedThing	positive regulation of convergent extension involved in rhombomere morphogenesis	Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.	got7fsn_ti	activation of convergent extension involved in rhombomere morphogenesis|up regulation of convergent extension involved in rhombomere morphogenesis|up-regulation of convergent extension involved in rhombomere morphogenesis|upregulation of convergent extension involved in rhombomere morphogenesis						dph	2015-04-10T21:21:24Z						biological_process											owl:Class	
GO:0090046	biolink:NamedThing	obsolete regulation of transcription regulator activity	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.	got7fsn_ti	regulation of transcription regulator activity				At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term.		tb	2009-08-07T10:19:57Z		True				biological_process											owl:Class	
GO:0097338	biolink:NamedThing	response to clozapine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.	got7fsn_ti							pr	2012-06-12T11:07:01Z						biological_process											owl:Class	
GO:0015662	biolink:NamedThing	P-type ion transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.	got7fsn_ti	ion transmembrane transporter activity, phosphorylative mechanism|P-type ATPase activity|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity	https://github.com/geneontology/go-ontology/issues/17164										Reactome:R-HSA-429157		molecular_function											owl:Class	
GO:0008248	biolink:NamedThing	obsolete pre-mRNA splicing factor activity	OBSOLETE. An activity involved in the removal of an intron from a pre-mRNA.	got7fsn_ti	pre-mRNA splicing factor activity				This term was made obsolete because it describes a biological process.	GO:0008380				True				molecular_function											owl:Class	
GO:1902831	biolink:NamedThing	positive regulation of spinal cord association neuron differentiation	Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation.	got7fsn_ti	upregulation of spinal cord association neuron differentiation|activation of spinal cord dorsal interneuron differentiation|activation of spinal cord association neuron differentiation|up regulation of spinal cord association neuron differentiation|up-regulation of spinal cord dorsal interneuron differentiation|up-regulation of spinal cord association neuron differentiation|positive regulation of spinal cord dorsal interneuron differentiation|up regulation of spinal cord dorsal interneuron differentiation|upregulation of spinal cord dorsal interneuron differentiation						mr	2014-03-31T17:12:38Z						biological_process											owl:Class	
GO:0006760	biolink:NamedThing	folic acid-containing compound metabolic process	The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.	got7fsn_ti	folate and derivative metabolism|vitamin B9 and derivative metabolic process|folate and derivative metabolic process|vitamin B9 and derivative metabolism|folic acid and derivative metabolism|folic acid-containing compound metabolism|folic acid and derivative metabolic process|folate-containing compound metabolism|folate-containing compound metabolic process|vitamin M and derivative metabolic process|vitamin M and derivative metabolism													biological_process											owl:Class	
GO:0047944	biolink:NamedThing	obsolete glutamate 1-kinase activity	OBSOLETE. Catalysis of the reaction: L-glutamate + ATP = alpha-L-glutamyl phosphate + ADP + H(+).	got7fsn_ti	ATP:L-glutamate 1-phosphotransferase activity				This term is slated for obsoletion. RHEA indicates the activity has been shown not to exist.					True				molecular_function											owl:Class	
GO:0043762	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905515	biolink:NamedThing	non-motile cilium assembly	The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.	got7fsn_ti	nonmotile cilium formation|nonmotile cilium assembly|nonmotile primary cilium assembly|sensory cilium assembly|nonmotile primary cilia assembly|immotile primary cilium assembly|non-motile cilium formation|sensory cilium biogenesis						pr	2016-09-30T11:55:15Z			GO:0035058			biological_process											owl:Class	
GO:0002675	biolink:NamedThing	positive regulation of acute inflammatory response	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.	got7fsn_ti	up-regulation of acute inflammatory response|activation of acute inflammatory response|up regulation of acute inflammatory response|upregulation of acute inflammatory response|stimulation of acute inflammatory response													biological_process											owl:Class	
GO:0014839	biolink:NamedThing	myoblast migration involved in skeletal muscle regeneration	The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti	mononucleate cell migration involved in skeletal muscle regeneration													biological_process											owl:Class	
GO:0045600	biolink:NamedThing	positive regulation of fat cell differentiation	Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.	got7fsn_ti	up-regulation of fat cell differentiation|stimulation of fat cell differentiation|activation of fat cell differentiation|positive regulation of adipocyte differentiation|up regulation of fat cell differentiation|positive regulation of adipocyte cell differentiation|upregulation of fat cell differentiation													biological_process											owl:Class	
GO:0039575	biolink:NamedThing	obsolete suppression by virus of host TYK2 activity by negative regulation of TYK2 tyrosine phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity by stopping, preventing or reducing phosphorylation and thereby activation of TYK2.	got7fsn_ti	inhibition by virus of host TYK2 phosphorylation|inhibition by virus of host TYK2 activation				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True				biological_process											owl:Class	
GO:1904801	biolink:NamedThing	positive regulation of neuron remodeling	Any process that activates or increases the frequency, rate or extent of neuron remodeling.	got7fsn_ti	positive regulation of axon pruning|up regulation of axon pruning|activation of neuronal remodeling|up-regulation of axon pruning|upregulation of neuronal remodeling|up-regulation of neuron remodeling|up regulation of neuron remodeling|up-regulation of neuronal remodeling|activation of neuron remodeling|upregulation of axon pruning|positive regulation of neuronal remodeling|activation of axon pruning|upregulation of neuron remodeling|up regulation of neuronal remodeling				cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype)		es	2015-11-09T13:47:07Z						biological_process											owl:Class	
GO:0140207	biolink:NamedThing	tripeptide import across plasma membrane	The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-02-22T15:49:55Z						biological_process											owl:Class	
GO:0002392	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046138	biolink:NamedThing	obsolete coenzyme and prosthetic group biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes and prosthetic groups.	got7fsn_ti	coenzyme and prosthetic group formation|coenzyme and prosthetic group biosynthesis|coenzyme and prosthetic group synthesis|coenzyme and prosthetic group biosynthetic process|coenzyme and prosthetic group anabolism				This term was made obsolete because it was replaced by more specific terms.	GO:0051191				True				biological_process											owl:Class	
GO:1900680	biolink:NamedThing	positive regulation of ferricrocin biosynthetic process	Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process.	got7fsn_ti	up regulation of ferricrocin synthesis|activation of ferricrocin biosynthetic process, peptide modification|up regulation of ferricrocin formation|up-regulation of ferricrocin biosynthetic process, peptide formation|positive regulation of ferricrocin formation|upregulation of ferricrocin synthesis|upregulation of ferricrocin anabolism|positive regulation of ferricrocin biosynthesis|activation of ferricrocin synthesis|up regulation of ferricrocin biosynthetic process, peptide formation|positive regulation of ferricrocin biosynthetic process, peptide modification|positive regulation of ferricrocin synthesis|up-regulation of ferricrocin formation|activation of ferricrocin biosynthetic process|up regulation of ferricrocin biosynthetic process, peptide modification|up-regulation of ferricrocin biosynthetic process, peptide modification|positive regulation of ferricrocin anabolism|positive regulation of ferricrocin biosynthetic process, peptide formation|up regulation of ferricrocin biosynthesis|activation of ferricrocin biosynthesis|up-regulation of ferricrocin anabolism|activation of ferricrocin formation|upregulation of ferricrocin formation|upregulation of ferricrocin biosynthetic process, peptide modification|upregulation of ferricrocin biosynthetic process, peptide formation|up regulation of ferricrocin biosynthetic process|up regulation of ferricrocin anabolism|upregulation of ferricrocin biosynthetic process|up-regulation of ferricrocin biosynthesis|up-regulation of ferricrocin synthesis|up-regulation of ferricrocin biosynthetic process|upregulation of ferricrocin biosynthesis|activation of ferricrocin anabolism|activation of ferricrocin biosynthetic process, peptide formation						di	2012-05-22T04:28:23Z						biological_process											owl:Class	
GO:0071650	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 5 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.	got7fsn_ti	negative regulation of RANTES production|negative regulation of CCL5 production|negative regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:1905878	biolink:NamedThing	obsolete invadopodium disassembly	OBSOLETE. The disaggregation of an invadopodium into its constituent components.	got7fsn_ti					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-01-27T20:44:16Z		True				biological_process											owl:Class	
GO:0042325	biolink:NamedThing	regulation of phosphorylation	Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0043887	biolink:NamedThing	melibiose:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in).	got7fsn_ti	thiomethylgalactoside permease II|melibiose:Na+ symporter activity|melibiose carrier protein|Na+-melibiose symporter activity|MelB|Na+:melibiose symporter activity|sodium:melibiose symporter activity|melibiose-Na+ symporter activity|sodium-melibiose symporter activity|Na+ (Li+)/melibiose symporter activity|melibiose/sodium symporter activity|sodium/melibiose symporter activity|melibiose permease|Na+/melibiose symporter activity|melibiose/Na+ symporter activity|melibiose-sodium symporter activity													molecular_function											owl:Class	
GO:0019276	biolink:NamedThing	UDP-N-acetylgalactosamine metabolic process	The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-N-acetylgalactosamine metabolism													biological_process											owl:Class	
GO:0042212	biolink:NamedThing	cresol metabolic process	The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.	got7fsn_ti	cresol metabolism|hydroxytoluene metabolism|hydroxytoluene metabolic process													biological_process											owl:Class	
GO:1901297	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.	got7fsn_ti	positive regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|activation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|up regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|upregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|up-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|activation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|up regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|upregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|up-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment						vk	2012-08-21T09:06:59Z						biological_process											owl:Class	
GO:1904774	biolink:NamedThing	negative regulation of ubiquinone biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process.	got7fsn_ti	inhibition of ubiquinone anabolism|negative regulation of ubiquinone biosynthesis|inhibition of coenzyme Q8 biosynthetic process|inhibition of ubiquinone formation|down-regulation of ubiquinone formation|negative regulation of coenzyme Q6 biosynthesis|down regulation of coenzyme Q9 biosynthesis|downregulation of ubiquinone biosynthesis|down regulation of coenzyme Q10 biosynthetic process|down-regulation of coenzyme Q biosynthesis|inhibition of ubiquinone synthesis|inhibition of coenzyme Q10 biosynthesis|down-regulation of ubiquinone synthesis|negative regulation of coenzyme Q9 biosynthesis|negative regulation of coenzyme Q6 biosynthetic process|down regulation of coenzyme Q8 biosynthetic process|down regulation of coenzyme Q8 biosynthesis|downregulation of coenzyme Q10 biosynthesis|inhibition of coenzyme Q6 biosynthesis|downregulation of coenzyme Q6 biosynthetic process|down-regulation of coenzyme Q biosynthetic process|negative regulation of coenzyme Q10 biosynthesis|down-regulation of coenzyme Q10 biosynthetic process|inhibition of coenzyme Q9 biosynthesis|down-regulation of ubiquinone biosynthetic process|inhibition of coenzyme Q6 biosynthetic process|downregulation of coenzyme Q biosynthesis|down-regulation of coenzyme Q9 biosynthetic process|downregulation of coenzyme Q biosynthetic process|down regulation of coenzyme Q6 biosynthesis|downregulation of coenzyme Q9 biosynthesis|down-regulation of coenzyme Q6 biosynthesis|downregulation of ubiquinone synthesis|down regulation of ubiquinone biosynthesis|downregulation of ubiquinone formation|negative regulation of coenzyme Q biosynthetic process|down regulation of coenzyme Q10 biosynthesis|negative regulation of ubiquinone anabolism|negative regulation of coenzyme Q10 biosynthetic process|negative regulation of coenzyme Q8 biosynthesis|negative regulation of ubiquinone synthesis|downregulation of coenzyme Q8 biosynthetic process|inhibition of ubiquinone biosynthetic process|down-regulation of ubiquinone biosynthesis|down regulation of coenzyme Q6 biosynthetic process|inhibition of coenzyme Q biosynthesis|inhibition of ubiquinone biosynthesis|down regulation of coenzyme Q biosynthetic process|down-regulation of coenzyme Q8 biosynthesis|negative regulation of coenzyme Q8 biosynthetic process|down-regulation of coenzyme Q10 biosynthesis|inhibition of coenzyme Q10 biosynthetic process|down-regulation of ubiquinone anabolism|negative regulation of ubiquinone formation|down regulation of ubiquinone synthesis|downregulation of coenzyme Q6 biosynthesis|downregulation of ubiquinone anabolism|negative regulation of coenzyme Q9 biosynthetic process|negative regulation of coenzyme Q biosynthesis|downregulation of coenzyme Q9 biosynthetic process|down regulation of ubiquinone formation|downregulation of coenzyme Q10 biosynthetic process|downregulation of ubiquinone biosynthetic process|inhibition of coenzyme Q biosynthetic process|down-regulation of coenzyme Q6 biosynthetic process|inhibition of coenzyme Q8 biosynthesis|down regulation of ubiquinone anabolism|inhibition of coenzyme Q9 biosynthetic process|down regulation of coenzyme Q biosynthesis|down regulation of ubiquinone biosynthetic process|down-regulation of coenzyme Q8 biosynthetic process|down-regulation of coenzyme Q9 biosynthesis|down regulation of coenzyme Q9 biosynthetic process|downregulation of coenzyme Q8 biosynthesis						sl	2015-10-28T21:21:20Z						biological_process											owl:Class	
GO:2000353	biolink:NamedThing	positive regulation of endothelial cell apoptotic process	Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.	got7fsn_ti	positive regulation of programmed cell death, endothelial cells|positive regulation of endothelial cell programmed cell death by apoptosis|positive regulation of killing of endothelial cells|positive regulation of endothelial cell apoptosis|positive regulation of programmed cell death of endothelial cells by apoptosis|positive regulation of apoptosis of endothelial cells						mah	2011-02-03T10:43:23Z						biological_process											owl:Class	
GO:0009492	biolink:NamedThing	obsolete 2Fe-2S electron transfer carrier	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	2Fe-2S electron transfer carrier			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:1903287	biolink:NamedThing	negative regulation of potassium ion import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane.	got7fsn_ti	inhibition of potassium ion import|downregulation of potassium ion uptake|negative regulation of potassium ion import|inhibition of potassium ion uptake|downregulation of potassium ion import|down regulation of potassium import|down-regulation of potassium import|down regulation of potassium ion import|down regulation of potassium ion uptake|down-regulation of potassium ion uptake|negative regulation of potassium import|inhibition of potassium import|down-regulation of potassium ion import|negative regulation of potassium ion uptake|downregulation of potassium import						rl	2014-08-11T14:26:24Z						biological_process											owl:Class	
GO:0019889	biolink:NamedThing	pteridine metabolic process	The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.	got7fsn_ti	pteridine metabolism													biological_process											owl:Class	
GO:0042762	biolink:NamedThing	regulation of sulfur metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.	got7fsn_ti	regulation of sulphur metabolism|regulation of sulfur metabolism|regulation of sulphur metabolic process													biological_process											owl:Class	
GO:0008155	biolink:NamedThing	obsolete larval behavior (sensu Drosophila)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	larval behavior (sensu Drosophila)			GO:0030537	This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term.					True				biological_process											owl:Class	
GO:0004194	biolink:NamedThing	obsolete pepsin A activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-Val2, Gln4-His5, Glu13-Ala14, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Gly23-Phe24, Phe24-Phe25 and Phe25-Tyr26 bonds in the B chain of insulin.	got7fsn_ti	elixir lactate of pepsin|pepsin D|P I|lactated pepsin|pepsin R|pepsin fortior|P II|fundus-pepsin|pepsin A activity|pepsin activity|lactated pepsin elixir			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1903851	biolink:NamedThing	negative regulation of cristae formation	Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation.	got7fsn_ti	downregulation of cristae formation|down regulation of cristae formation|down-regulation of cristae formation|inhibition of cristae formation				AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype		pad	2015-01-27T09:42:33Z						biological_process											owl:Class	
GO:1905919	biolink:NamedThing	negative regulation of CoA-transferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity.	got7fsn_ti	down regulation of CoA-transferase activity|inhibition of CoA-transferase activity|down-regulation of CoA-transferase activity|downregulation of CoA-transferase activity						bc	2017-02-08T13:00:56Z						biological_process											owl:Class	
GO:0071701	biolink:NamedThing	regulation of MAPK export from nucleus	Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm.	got7fsn_ti	regulation of MAPK export from cell nucleus|regulation of MAPK-nucleus export|regulation of MAPK export out of nucleus|regulation of MAPK transport from nucleus to cytoplasm|regulation of cytoplasmic translocation of mitogen-activated protein kinase|regulation of cytoplasmic translocation of MAP kinase						mah	2010-03-02T01:24:12Z						biological_process											owl:Class	
GO:0045907	biolink:NamedThing	positive regulation of vasoconstriction	Any process that activates or increases the frequency, rate or extent of vasoconstriction.	got7fsn_ti	activation of vasoconstriction|up-regulation of vasoconstriction|stimulation of vasoconstriction|upregulation of vasoconstriction|up regulation of vasoconstriction													biological_process											owl:Class	
GO:0002845	biolink:NamedThing	positive regulation of tolerance induction to tumor cell	Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell.	got7fsn_ti	up-regulation of tolerance induction to tumor cell|up regulation of tolerance induction to tumor cell|upregulation of tolerance induction to tumor cell|activation of tolerance induction to tumor cell|positive regulation of tolerance induction to tumour cell|stimulation of tolerance induction to tumor cell													biological_process											owl:Class	
GO:1902500	biolink:NamedThing	vacuolar HOPS complex	Any HOPS complex that is part of a vacuolar membrane.	got7fsn_ti	vacuolar membrane HOPS complex						tb	2013-11-14T00:09:50Z						cellular_component											owl:Class	
GO:1904403	biolink:NamedThing	cellular response to nocodazole	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.	got7fsn_ti							sl	2015-06-23T21:10:52Z						biological_process											owl:Class	
GO:0032678	biolink:NamedThing	regulation of interleukin-9 production	Any process that modulates the frequency, rate, or extent of interleukin-9 production.	got7fsn_ti	regulation of interleukin-9 biosynthetic process|regulation of IL-9 production										GO:0045417			biological_process											owl:Class	
GO:1902133	biolink:NamedThing	(+)-secoisolariciresinol metabolic process	The chemical reactions and pathways involving (+)-secoisolariciresinol.	got7fsn_ti	(+)-secoisolariciresinol metabolism						ms	2013-05-21T08:50:04Z						biological_process											owl:Class	
GO:0098537	biolink:NamedThing	obsolete lobed nucleus	OBSOLETE. Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin.  Examples include the nuclei of mature basophils, eosinophils and neutrophils in mice and humans.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20764			This term was obsoleted because it does not correspond to a specific type of nucleus, it is a morphologically different nucleus present in certain cell types.		dos	2013-10-22T18:31:36Z		True				cellular_component											owl:Class	
GO:0052349	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont reactive oxygen species production	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of defense-related symbiont metabolic burst|positive regulation by organism of defense-related symbiont ROI production|positive regulation by organism of defense-related symbiont AOS production|positive regulation by organism of defense-related symbiont active oxygen species production|positive regulation by organism of defense-related symbiont reactive oxygen species production|positive regulation by organism of defense-related symbiont reactive oxygen intermediate production|positive regulation by organism of defense-related symbiont ROS production|positive regulation by organism of defense-related symbiont oxidative burst|positive regulation by organism of defense-related symbiont reactive oxidative species production|positive regulation by organism of defense-related symbiont respiratory burst				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0031621	biolink:NamedThing	negative regulation of fever generation	Any process that stops, prevents, or reduces the rate or extent of fever generation.	got7fsn_ti	downregulation of fever|down-regulation of fever|down regulation of fever|inhibition of fever|negative regulation of pyrexia													biological_process											owl:Class	
GO:0035305	biolink:NamedThing	negative regulation of dephosphorylation	Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.	got7fsn_ti	downregulation of dephosphorylation|inhibition of dephosphorylation|down-regulation of dephosphorylation|down regulation of dephosphorylation													biological_process											owl:Class	
GO:0043573	biolink:NamedThing	leucoplast fission	The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.	got7fsn_ti														biological_process											owl:Class	
GO:0002759	biolink:NamedThing	regulation of antimicrobial humoral response	Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.	got7fsn_ti														biological_process											owl:Class	
GO:0009667	biolink:NamedThing	plastid inner membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid.	got7fsn_ti	plastid inner membrane organisation|plastid inner membrane organization and biogenesis													biological_process											owl:Class	
GO:0015744	biolink:NamedThing	succinate transport	The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0008636	biolink:NamedThing	obsolete activation of caspase activity by protein phosphorylation	OBSOLETE. Upregulation of the activity of a caspase, a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group.	got7fsn_ti	caspase activation via phosphorylation|activation of caspase activity by protein phosphorylation|activation of caspase activity by protein amino acid phosphorylation				This term was made obsolete because it is ill-defined: phosphorylation regulates the activity of caspases, but it doesn't activate them (caspases are only activated upon cleavage).					True				biological_process											owl:Class	
GO:0035542	biolink:NamedThing	regulation of SNARE complex assembly	Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	got7fsn_ti							bf	2010-05-10T01:49:35Z						biological_process											owl:Class	
GO:0061992	biolink:NamedThing	obsolete ATP-dependent chaperone mediated protein folding	OBSOLETE. The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and dependent on ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21930			This term was obsoleted because it represents a molecular function.	GO:0140662|GO:0006457	dph	2018-02-15T23:34:28Z		True				biological_process											owl:Class	
GO:0034253	biolink:NamedThing	positive regulation of cellular amide catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.	got7fsn_ti	positive regulation of amide catabolism|positive regulation of amide degradation|positive regulation of amide breakdown													biological_process											owl:Class	
GO:1901680	biolink:NamedThing	sulfur-containing amino acid secondary active transmembrane transporter activity	Enables the transfer of sulfur-containing amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti							pr	2012-11-22T16:16:48Z						molecular_function											owl:Class	
GO:1903865	biolink:NamedThing	sigma factor antagonist complex	A protein complex which is capable of sigma factor antagonist activity.	got7fsn_ti							bhm	2015-02-04T15:39:34Z						cellular_component											owl:Class	
GO:2000375	biolink:NamedThing	negative regulation of oxygen metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.	got7fsn_ti	negative regulation of diatomic oxygen metabolic process|negative regulation of oxygen metabolism						mah	2011-02-11T02:03:44Z						biological_process											owl:Class	
GO:1901978	biolink:NamedThing	positive regulation of cell cycle checkpoint	Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint.	got7fsn_ti	activation of cell cycle checkpoint|up regulation of cell cycle checkpoint|positive regulation of G1/S checkpoint|positive regulation of G1/S transition checkpoint|upregulation of cell cycle checkpoint|up-regulation of cell cycle checkpoint						jl	2013-03-06T15:10:34Z			GO:2001052			biological_process											owl:Class	
GO:1901516	biolink:NamedThing	aspyridone A metabolic process	The chemical reactions and pathways involving aspyridone A.	got7fsn_ti	aspyridone A metabolism						di	2012-10-18T18:31:28Z						biological_process											owl:Class	
GO:0062149	biolink:NamedThing	detection of stimulus involved in sensory perception of pain	The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.	got7fsn_ti							dph	2019-09-13T13:48:47Z						biological_process											owl:Class	
GO:1900023	biolink:NamedThing	positive regulation of D-erythro-sphingosine kinase activity	Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity.	got7fsn_ti	up regulation of D-erythro-sphingosine kinase activity|up regulation of sphingosine kinase activity|positive regulation of sphingosine kinase activity						bf	2012-01-11T04:30:33Z						biological_process											owl:Class	
GO:1904841	biolink:NamedThing	TORC2 complex binding	Binding to a TORC2 complex.	got7fsn_ti	TORC 2 complex binding|TORC2 binding|TOR complex 2 binding|rapamycin and nutrient-insensitive TOR complex binding|mTORC2 binding				Binding to a TORC2 complex, a protein complex that mediates the phosphorylation of protein kinase B		pf	2015-12-07T16:59:44Z						molecular_function											owl:Class	
GO:0002676	biolink:NamedThing	regulation of chronic inflammatory response	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.	got7fsn_ti														biological_process											owl:Class	
GO:0070607	biolink:NamedThing	regulation of cell wall (1->3)-alpha-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.	got7fsn_ti	regulation of cell wall alpha-1,3 glucan metabolic process|regulation of cell wall alpha-1,3 glucan metabolism|regulation of cell wall 1,3-alpha-glucan metabolism|regulation of cell wall 1,3-alpha-glucan metabolic process						mah	2009-04-29T01:24:57Z						biological_process											owl:Class	
GO:2001282	biolink:NamedThing	negative regulation of muscle cell chemotaxis toward tendon cell	Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells.	got7fsn_ti	arrest of muscle cell chemotaxis|negative regulation of muscle cell chemotaxis towards tendon cell|negative regulation of muscle cell attraction						bf	2011-12-15T10:39:42Z						biological_process											owl:Class	
GO:0006683	biolink:NamedThing	galactosylceramide catabolic process	The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.	got7fsn_ti	galactosylceramide degradation|galactosylceramide catabolism|galactosylceramide breakdown													biological_process											owl:Class	
GO:0051150	biolink:NamedThing	regulation of smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1900693	biolink:NamedThing	negative regulation of (+)-kotanin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process.	got7fsn_ti	inhibition of (+)-kotanin biosynthetic process|down-regulation of (+)-kotanin synthesis|down regulation of (+)-kotanin anabolism|down-regulation of (+)-kotanin formation|down regulation of (+)-kotanin formation|inhibition of (+)-kotanin formation|down regulation of (+)-kotanin synthesis|down-regulation of (+)-kotanin biosynthesis|down regulation of (+)-kotanin biosynthesis|downregulation of (+)-kotanin anabolism|negative regulation of (+)-kotanin biosynthesis|downregulation of (+)-kotanin biosynthetic process|down regulation of (+)-kotanin biosynthetic process|inhibition of (+)-kotanin anabolism|negative regulation of (+)-kotanin anabolism|negative regulation of (+)-kotanin synthesis|down-regulation of (+)-kotanin biosynthetic process|inhibition of (+)-kotanin biosynthesis|downregulation of (+)-kotanin biosynthesis|down-regulation of (+)-kotanin anabolism|inhibition of (+)-kotanin synthesis|negative regulation of (+)-kotanin formation|downregulation of (+)-kotanin synthesis|downregulation of (+)-kotanin formation						di	2012-05-22T04:53:26Z						biological_process											owl:Class	
GO:1900050	biolink:NamedThing	negative regulation of histone exchange	Any process that stops, prevents or reduces the frequency, rate or extent of histone exchange.	got7fsn_ti	down-regulation of histone chaperone|down regulation of histone chaperone|inhibition of histone replacement|negative regulation of histone chaperone|downregulation of histone exchange|negative regulation of histone replacement|down-regulation of histone exchange|inhibition of histone exchange|down-regulation of histone replacement|downregulation of histone chaperone|down regulation of histone exchange|inhibition of histone chaperone|downregulation of histone replacement|down regulation of histone replacement						se	2012-01-19T10:59:09Z						biological_process											owl:Class	
GO:1901221	biolink:NamedThing	positive regulation of cardiac chamber morphogenesis	Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis.	got7fsn_ti	upregulation of cardiac chamber morphogenesis|activation of cardiac chamber morphogenesis|activation of heart chamber morphogenesis|up regulation of heart chamber morphogenesis|up regulation of cardiac chamber morphogenesis|up-regulation of cardiac chamber morphogenesis|positive regulation of heart chamber morphogenesis|up-regulation of heart chamber morphogenesis|upregulation of heart chamber morphogenesis						rl	2012-08-06T17:59:42Z						biological_process											owl:Class	
GO:0006110	biolink:NamedThing	regulation of glycolytic process	Any process that modulates the frequency, rate or extent of glycolysis.	got7fsn_ti	regulation of glycolysis involved in cellular glucose homeostasis										GO:0090525			biological_process											owl:Class	
GO:1903142	biolink:NamedThing	positive regulation of establishment of endothelial barrier	Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier.	got7fsn_ti	upregulation of establishment of endothelial barrier|activation of establishment of endothelial barrier|up-regulation of establishment of endothelial barrier|up regulation of establishment of endothelial barrier						als	2014-07-01T12:12:52Z						biological_process											owl:Class	
GO:0062032	biolink:NamedThing	cichorine biosynthetic process	The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi.	got7fsn_ti	cichorine synthesis|cichorine formation|cichorine biosynthesis|cichorine anabolism						dph	2018-04-19T16:22:09Z						biological_process											owl:Class	
GO:0009326	biolink:NamedThing	formate dehydrogenase complex	An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2).	got7fsn_ti												EC:1.17.1.9		cellular_component											owl:Class	
GO:1904001	biolink:NamedThing	obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage.	got7fsn_ti	up regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|positive regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|activation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|up regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|activation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|up-regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|up-regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|upregulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|upregulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		pr	2015-03-05T21:25:42Z		True				biological_process											owl:Class	
GO:0002614	biolink:NamedThing	negative regulation of monocyte antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.	got7fsn_ti	downregulation of monocyte antigen processing and presentation|down-regulation of monocyte antigen processing and presentation|down regulation of monocyte antigen processing and presentation|inhibition of monocyte antigen processing and presentation													biological_process											owl:Class	
GO:0110119	biolink:NamedThing	positive regulation of very-low-density lipoprotein particle clearance	Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance.	got7fsn_ti							kmv	2018-07-27T14:13:47Z						biological_process											owl:Class	
GO:0007346	biolink:NamedThing	regulation of mitotic cell cycle	Any process that modulates the rate or extent of progress through the mitotic cell cycle.	got7fsn_ti	regulation of mitotic cell cycle progression|mitotic cell cycle regulator|mitotic cell cycle modulation|regulation of progression through mitotic cell cycle|mitotic cell cycle regulation|modulation of mitotic cell cycle progression													biological_process											owl:Class	
GO:0045751	biolink:NamedThing	negative regulation of Toll signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway.	got7fsn_ti	negative regulation of Tl signaling pathway|downregulation of Toll signaling pathway|down-regulation of Toll signaling pathway|inhibition of Toll signaling pathway|negative regulation of Tl signalling pathway|down regulation of Toll signaling pathway													biological_process											owl:Class	
GO:0008564	biolink:NamedThing	protein-exporting ATPase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.	got7fsn_ti	ATPase-coupled protein transporter activity				Represents ATP- hydrolyzing enzymes of the general secretory pathway (Sec or Type II), of the virulence-related secretory pathway (Type III) and of the conjugal DNA-protein transfer pathway (Type IV). Type II enzymes occur in bacteria, archaea and eukaryotes, whereas type III and type IV enzymes occur in bacteria where they form components of a multi-subunit complex.							MetaCyc:3.6.3.50-RXN|EC:7.4.2.8		molecular_function											owl:Class	
GO:1905639	biolink:NamedThing	positive regulation of mitochondrial mRNA catabolic process	Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process.	got7fsn_ti	up regulation of mitochondrial mRNA catabolic process|upregulation of mitochondrial mRNA catabolic process|activation of mitochondrial mRNA catabolic process|up-regulation of mitochondrial mRNA catabolic process						tb	2016-11-03T20:24:13Z						biological_process											owl:Class	
GO:1901911	biolink:NamedThing	adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).	got7fsn_ti	adenosine 5'-(hexahydrogen pentaphosphate) breakdown|adenosine 5'-(hexahydrogen pentaphosphate) degradation|adenosine 5'-(hexahydrogen pentaphosphate) catabolism						al	2013-02-13T14:18:03Z						biological_process											owl:Class	
GO:1902511	biolink:NamedThing	negative regulation of apoptotic DNA fragmentation	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.	got7fsn_ti	inhibition of apoptotic DNA fragmentation|downregulation of endonucleolytic DNA catabolic process involved in apoptosis|down-regulation of apoptotic DNA fragmentation|down-regulation of endonucleolytic DNA catabolic process involved in apoptosis|down-regulation of DNA catabolism during apoptosis|negative regulation of endonucleolytic DNA catabolic process involved in apoptosis|down regulation of DNA fragmentation involved in apoptotic nuclear change|down regulation of apoptotic DNA fragmentation|inhibition of endonucleolytic DNA catabolic process involved in apoptosis|downregulation of DNA catabolism during apoptosis|inhibition of DNA catabolism during apoptosis|down regulation of DNA catabolism during apoptosis|negative regulation of DNA fragmentation involved in apoptotic nuclear change|down-regulation of DNA fragmentation involved in apoptotic nuclear change|down-regulation of DNA catabolic process during apoptosis|downregulation of apoptotic DNA fragmentation|negative regulation of DNA catabolism during apoptosis|down regulation of endonucleolytic DNA catabolic process involved in apoptosis|negative regulation of DNA catabolic process during apoptosis|inhibition of DNA fragmentation involved in apoptotic nuclear change|down regulation of DNA catabolic process during apoptosis|downregulation of DNA catabolic process during apoptosis|inhibition of DNA catabolic process during apoptosis|downregulation of DNA fragmentation involved in apoptotic nuclear change						hjd	2013-11-15T18:28:41Z						biological_process											owl:Class	
GO:0031684	biolink:NamedThing	obsolete heterotrimeric G-protein complex cycle	OBSOLETE. The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits.	got7fsn_ti					The reason for obsoleting is that it is an arbitrary grouping term that groups the molecular functions required for the G-protein complex cycle, and this is not a bona fide biological process.					True				biological_process											owl:Class	
GO:1901406	biolink:NamedThing	positive regulation of tetrapyrrole catabolic process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process.	got7fsn_ti	positive regulation of tetrapyrrole breakdown|activation of tetrapyrrole degradation|up-regulation of tetrapyrrole degradation|up regulation of tetrapyrrole catabolic process|upregulation of tetrapyrrole breakdown|upregulation of tetrapyrrole catabolic process|upregulation of tetrapyrrole degradation|up regulation of tetrapyrrole catabolism|up-regulation of tetrapyrrole catabolism|activation of tetrapyrrole catabolic process|upregulation of tetrapyrrole catabolism|up regulation of tetrapyrrole breakdown|activation of tetrapyrrole catabolism|up regulation of tetrapyrrole degradation|positive regulation of tetrapyrrole degradation|positive regulation of tetrapyrrole catabolism|up-regulation of tetrapyrrole catabolic process|activation of tetrapyrrole breakdown|up-regulation of tetrapyrrole breakdown						tt	2012-10-01T14:39:40Z						biological_process											owl:Class	
GO:1905914	biolink:NamedThing	positive regulation of calcium ion export across plasma membrane	Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane.	got7fsn_ti	activation of calcium ion export from cell|up-regulation of calcium ion export from cell|up regulation of calcium ion export from cell|positive regulation of calcium ion efflux from cell|upregulation of calcium ion export from cell|activation of calcium ion efflux from cell|upregulation of calcium ion efflux from cell|positive regulation of calcium ion export from cell|up-regulation of calcium ion efflux from cell|up regulation of calcium ion efflux from cell						rph	2017-02-07T13:20:56Z						biological_process											owl:Class	
GO:0006669	biolink:NamedThing	sphinganine-1-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.	got7fsn_ti	sphinganine-1-phosphate anabolism|sphinganine-1-phosphate synthesis|sphinganine-1-phosphate formation|dihydrosphingosine-1-phosphate biosynthetic process|dihydrosphingosine-1-phosphate biosynthesis|sphinganine-1-phosphate biosynthesis													biological_process											owl:Class	
GO:1990507	biolink:NamedThing	obsolete ATP-independent chaperone mediated protein folding	OBSOLETE. The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and independent of ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21930			This term was obsoleted because it represents a molecular function.	GO:0044183|GO:0006457	rb	2014-10-01T23:55:05Z		True				biological_process											owl:Class	
GO:1903185	biolink:NamedThing	L-dopa biosynthetic process	The chemical reactions and pathways resulting in the formation of L-dopa.	got7fsn_ti	L-dopa biosynthesis|L-dopa synthesis|L-dopa anabolism|L-dopa formation						bf	2014-07-14T15:06:06Z						biological_process											owl:Class	
GO:1901936	biolink:NamedThing	beta-caryophyllene catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.	got7fsn_ti	beta-caryophyllene catabolism|beta-caryophyllene breakdown|beta-caryophyllene degradation						ms	2013-02-18T14:55:13Z						biological_process											owl:Class	
GO:0075080	biolink:NamedThing	obsolete negative regulation by host of symbiont receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0055092	biolink:NamedThing	sterol homeostasis	Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0005710	biolink:NamedThing	obsolete metaphase chromosome	OBSOLETE. A chromosome found in the cell during metaphase. Typically, sister chromatids are held together at their centromeres and chromosomes are covered with a large number of molecules, including ribonucleoproteins.	got7fsn_ti	metaphase chromosome				This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000794|GO:0000793				True				cellular_component											owl:Class	
GO:0071297	biolink:NamedThing	cellular response to cobalamin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.	got7fsn_ti	cellular response to vitamin B12						mah	2009-12-10T04:28:45Z						biological_process											owl:Class	
GO:1901849	biolink:NamedThing	nicotinate biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinate.	got7fsn_ti	nicotinate synthesis|nicotinate anabolism|nicotinate formation|nicotinate biosynthesis						yaf	2013-01-28T11:23:57Z						biological_process											owl:Class	
GO:1905766	biolink:NamedThing	positive regulation of protection from non-homologous end joining at telomere	Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere.	got7fsn_ti	activation of protection from NHEJ-mediated telomere fusion|up regulation of protection from NHEJ-mediated telomere fusion|up regulation of protection from non-homologous end joining at telomere|positive regulation of protection from NHEJ-mediated telomere fusion|activation of protection from non-homologous end joining at telomere|up-regulation of protection from non-homologous end joining at telomere|up-regulation of protection from NHEJ-mediated telomere fusion|upregulation of protection from non-homologous end joining at telomere|upregulation of protection from NHEJ-mediated telomere fusion						nc	2016-12-20T11:28:39Z						biological_process											owl:Class	
GO:1900422	biolink:NamedThing	obsolete positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of cellular alcohol catabolic process.	got7fsn_ti	upregulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|activation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-24T05:13:25Z		True				biological_process											owl:Class	
GO:1904049	biolink:NamedThing	negative regulation of spontaneous neurotransmitter secretion	Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion.	got7fsn_ti	inhibition of spontaneous neurotransmitter secretion|down-regulation of stimulus-independent neurotransmitter secretion|down-regulation of spontaneous neurotransmitter secretion|negative regulation of stimulus-independent neurotransmitter secretion|down regulation of stimulus-independent neurotransmitter secretion|down regulation of spontaneous neurotransmitter secretion|downregulation of stimulus-independent neurotransmitter secretion|inhibition of stimulus-independent neurotransmitter secretion|downregulation of spontaneous neurotransmitter secretion				An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).		pad	2015-03-17T10:37:17Z						biological_process											owl:Class	
GO:0090199	biolink:NamedThing	regulation of release of cytochrome c from mitochondria	Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.	got7fsn_ti					The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly regulate this process.		tb	2009-12-18T11:35:20Z						biological_process											owl:Class	
GO:2000756	biolink:NamedThing	regulation of peptidyl-lysine acetylation	Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation.	got7fsn_ti							yaf	2011-06-16T09:51:26Z						biological_process											owl:Class	
GO:0046322	biolink:NamedThing	negative regulation of fatty acid oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.	got7fsn_ti	inhibition of fatty acid oxidation|down-regulation of fatty acid oxidation|down regulation of fatty acid oxidation|downregulation of fatty acid oxidation													biological_process											owl:Class	
GO:1900080	biolink:NamedThing	positive regulation of arginine biosynthetic process	Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process.	got7fsn_ti	up-regulation of arginine formation|up regulation of arginine biosynthesis|upregulation of arginine anabolism|activation of arginine synthesis|up-regulation of arginine biosynthetic process|upregulation of arginine biosynthetic process|activation of arginine biosynthesis|upregulation of arginine formation|activation of arginine anabolism|positive regulation of arginine biosynthesis|activation of arginine formation|up regulation of arginine synthesis|up regulation of arginine formation|up regulation of arginine anabolism|positive regulation of arginine formation|positive regulation of arginine synthesis|up-regulation of arginine biosynthesis|up-regulation of arginine synthesis|upregulation of arginine synthesis|upregulation of arginine biosynthesis|up regulation of arginine biosynthetic process|activation of arginine biosynthetic process|up-regulation of arginine anabolism|positive regulation of arginine anabolism						pr	2012-02-01T03:57:41Z						biological_process											owl:Class	
GO:0110101	biolink:NamedThing	L-valine transmembrane import into vacuole	The directed movement of L-valine into the vacuole across the vacuolar membrane.	got7fsn_ti							kmv	2018-03-14T19:56:06Z						biological_process											owl:Class	
GO:0061016	biolink:NamedThing	snRNA localization to Cajal body	The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body.	got7fsn_ti							dph	2010-01-29T02:40:50Z						biological_process											owl:Class	
GO:1904156	biolink:NamedThing	DN3 thymocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.	got7fsn_ti							dph	2015-04-15T12:53:00Z						biological_process											owl:Class	
GO:0072397	biolink:NamedThing	obsolete detection of stimulus involved in cytokinesis checkpoint	OBSOLETE. The series of events in which information about the formation and integrity of cytokinetic structures, such as the contractile ring, is received and converted into a molecular signal, contributing to a cytokinesis checkpoint.	got7fsn_ti	cytokinesis checkpoint sensor mechanism|septin checkpoint sensor mechanism|cytokinesis checkpoint sensor process|sensing involved in cytokinesis checkpoint|detection of stimulus involved in septin checkpoint|sensing involved in septin checkpoint|septin checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:18:11Z		True	GO:0072418			biological_process											owl:Class	
GO:0015696	biolink:NamedThing	ammonium transport	The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.	got7fsn_ti	ammonia transport													biological_process											owl:Class	
GO:0004245	biolink:NamedThing	obsolete neprilysin activity	OBSOLETE. Catalysis of the preferential cleavage at the amino group of hydrophobic residues in insulin, casein, hemoglobin, and a number of other proteins and polypeptides.	got7fsn_ti	neutral endopeptidase 24.11|endopeptidase-2 activity|neutral metallendopeptidase activity|CD10|CALLA (common acute lymphoblastic leukemia-associated) antigens|CALLA|kidney-brush-border neutral peptidase|kidney-brush-border neutral endopeptidase|enkephalinase activity|CALLA antigen|CALLA glycoprotein|acute lymphoblastic leukemia antigen|endopeptidase 24.11|common acute lymphoblastic leukemia antigen|neutral endopeptidase activity|membrane metalloendopeptidase activity|neprilysin activity|kidney-brush-border neutral proteinase activity|common acute lymphoblastic leukemia-associated antigens|CALLA glycoproteins			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0001575	biolink:NamedThing	globoside metabolic process	The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.	got7fsn_ti	globoside metabolism													biological_process											owl:Class	
GO:1900285	biolink:NamedThing	regulation of cellotriose transport	Any process that modulates the frequency, rate or extent of cellotriose transport.	got7fsn_ti							tt	2012-04-05T05:56:46Z						biological_process											owl:Class	
GO:0008337	biolink:NamedThing	obsolete selectin	OBSOLETE. A class of cell adhesion molecules that bind to carbohydrate via a lectin-like domain; integral membrane glycoproteins.	got7fsn_ti	selectin				This term was made obsolete because it describes a class of gene products.	GO:0005102|GO:0016021|GO:0030246|GO:0050839|GO:0007155				True				molecular_function											owl:Class	
GO:0072389	biolink:NamedThing	flavin adenine dinucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.	got7fsn_ti	FAD or FADH2 catabolic process|flavin adenine dinucleotide breakdown|flavin adenine dinucleotide catabolism|flavin adenine dinucleotide degradation						mah	2010-12-02T04:28:02Z						biological_process											owl:Class	
GO:1902100	biolink:NamedThing	negative regulation of metaphase/anaphase transition of cell cycle	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.	got7fsn_ti	inhibition of metaphase/anaphase transition of cell cycle|down regulation of metaphase/anaphase transition of cell cycle|down-regulation of metaphase/anaphase transition of cell cycle|downregulation of metaphase/anaphase transition of cell cycle						jl	2013-05-02T12:45:20Z						biological_process											owl:Class	
GO:1902626	biolink:NamedThing	assembly of large subunit precursor of preribosome	The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.	got7fsn_ti	66S preribosome formation|66S preribosome assembly|preribosome, large subunit precursor formation						tb	2014-01-16T19:38:05Z						biological_process											owl:Class	
GO:0071296	biolink:NamedThing	cellular response to biotin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.	got7fsn_ti	cellular response to coenzyme R|cellular response to Bios IIB|cellular response to vitamin B7|cellular response to vitamin H						mah	2009-12-10T04:28:22Z						biological_process											owl:Class	
GO:0005707	biolink:NamedThing	obsolete interphase chromosome	OBSOLETE. A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently.	got7fsn_ti	interphase chromosome				This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0005694				True				cellular_component											owl:Class	
GO:0060906	biolink:NamedThing	negative regulation of heterochromatin assembly by small RNA	Any process that decreases the frequency, rate or extent of heterochromatin assembly by small RNA.	got7fsn_ti	negative regulation of RNAi-mediated heterochromatin assembly|negative regulation of chromatin silencing by small RNA	https://github.com/geneontology/go-ontology/issues/19112					dph	2009-08-14T01:22:24Z						biological_process											owl:Class	
GO:1902212	biolink:NamedThing	negative regulation of prolactin signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.	got7fsn_ti	down regulation of prolactin signaling pathway|down-regulation of prolactin-mediated signaling pathway|down-regulation of PRL signaling pathway|inhibition of PRL signaling pathway|down regulation of prolactin-mediated signaling pathway|downregulation of PRL signaling pathway|down regulation of PRL signaling pathway|downregulation of prolactin-mediated signaling pathway|negative regulation of prolactin-mediated signaling pathway|downregulation of prolactin signaling pathway|down-regulation of prolactin signaling pathway|inhibition of prolactin signaling pathway|inhibition of prolactin-mediated signaling pathway|negative regulation of PRL signaling pathway						lb	2013-06-12T10:10:12Z						biological_process											owl:Class	
GO:2000589	biolink:NamedThing	regulation of metanephric mesenchymal cell migration	Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration.	got7fsn_ti	regulation of metanephric mesenchyme chemotaxis						bf	2011-04-07T03:29:43Z						biological_process											owl:Class	
GO:1904612	biolink:NamedThing	response to 2,3,7,8-tetrachlorodibenzodioxine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.	got7fsn_ti	response to dioxin|response to TCDD						sl	2015-08-27T19:01:52Z						biological_process											owl:Class	
GO:2000680	biolink:NamedThing	obsolete regulation of rubidium ion transport	OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transport.	got7fsn_ti	regulation of rubidium cation transport|regulation of Rb+ transport				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-10T10:54:31Z		True				biological_process											owl:Class	
GO:0015521	biolink:NamedThing	obsolete bicyclomycin/sulfathiazole:hydrogen antiporter activity	OBSOLETE. Catalysis of the reaction: (bicyclomycin or sulfathiazole)(in) + H+(out) = (bicyclomycin or sulfathiazole)(out) + H+(in).	got7fsn_ti	bicyclomycin/sulfathiazole:hydrogen antiporter activity|bicyclomycin/sulfathiazole:proton antiporter activity|bicyclomycin/sulphathiazole:hydrogen antiporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0045119|GO:0015545|GO:0015546				True				molecular_function											owl:Class	
GO:0007257	biolink:NamedThing	obsolete activation of JUN kinase activity	OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase (JNK).	got7fsn_ti	activation of SAPK activity	https://github.com/geneontology/go-ontology/issues/21307				GO:0007254|GO:0043539				True				biological_process											owl:Class	
GO:0046260	biolink:NamedThing	trinitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.	got7fsn_ti	trinitrotoluene breakdown|trinitrotoluene degradation|trinitrotoluene catabolism													biological_process											owl:Class	
GO:0075100	biolink:NamedThing	obsolete positive regulation by host of symbiont protein kinase-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0090126	biolink:NamedThing	protein-containing complex assembly involved in synapse maturation	The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation.	got7fsn_ti	protein complex assembly involved in synapse maturation						tb	2009-12-07T02:49:28Z						biological_process											owl:Class	
UBERON:0003915	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006225	biolink:NamedThing	UDP biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate.	got7fsn_ti	UDP formation|UDP biosynthesis|UDP synthesis|UDP anabolism													biological_process											owl:Class	
GO:1900399	biolink:NamedThing	positive regulation of pyrimidine nucleotide biosynthetic process	Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.	got7fsn_ti	positive regulation of pyrimidine nucleotide biosynthesis|up-regulation of pyrimidine nucleotide anabolism|upregulation of pyrimidine nucleotide biosynthesis|upregulation of pyrimidine nucleotide synthesis|up regulation of pyrimidine nucleotide synthesis|activation of pyrimidine nucleotide anabolism|up-regulation of pyrimidine nucleotide formation|positive regulation of pyrimidine nucleotide synthesis|upregulation of pyrimidine nucleotide formation|up regulation of pyrimidine nucleotide formation|activation of pyrimidine nucleotide biosynthetic process|activation of pyrimidine nucleotide biosynthesis|activation of pyrimidine nucleotide formation|up regulation of pyrimidine nucleotide biosynthetic process|upregulation of pyrimidine nucleotide biosynthetic process|up regulation of pyrimidine nucleotide anabolism|activation of pyrimidine nucleotide synthesis|positive regulation of pyrimidine nucleotide anabolism|up regulation of pyrimidine nucleotide biosynthesis|positive regulation of pyrimidine nucleotide formation|up-regulation of pyrimidine nucleotide biosynthetic process|upregulation of pyrimidine nucleotide anabolism|up-regulation of pyrimidine nucleotide synthesis|up-regulation of pyrimidine nucleotide biosynthesis						jh	2012-04-19T01:05:50Z						biological_process											owl:Class	
GO:0010828	biolink:NamedThing	positive regulation of glucose transmembrane transport	Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	positive regulation of glucose transport													biological_process											owl:Class	
GO:1905178	biolink:NamedThing	regulation of cardiac muscle tissue regeneration	Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration.	got7fsn_ti							rph	2016-05-05T11:30:48Z						biological_process											owl:Class	
GO:1904151	biolink:NamedThing	positive regulation of microglial cell mediated cytotoxicity	Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.	got7fsn_ti	up-regulation of microglial cell mediated cytotoxicity|upregulation of microglial cell mediated cytotoxicity|activation of microglial cell mediated cytotoxicity|up regulation of microglial cell mediated cytotoxicity						nc	2015-04-15T08:05:42Z						biological_process											owl:Class	
GO:0048147	biolink:NamedThing	negative regulation of fibroblast proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.	got7fsn_ti	down regulation of fibroblast proliferation|inhibition of fibroblast proliferation|downregulation of fibroblast proliferation|down-regulation of fibroblast proliferation													biological_process											owl:Class	
GO:0042202	biolink:NamedThing	N-cyclopropylmelamine catabolic process	The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide.	got7fsn_ti	cyromazine catabolic process|N-cyclopropylmelamine degradation|cyromazine catabolism|N-cyclopropylmelamine catabolism|N-cyclopropylmelamine breakdown											UM-BBD_pathwayID:cpm		biological_process											owl:Class	
GO:1903306	biolink:NamedThing	negative regulation of regulated secretory pathway	Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway.	got7fsn_ti	inhibition of regulated secretory pathway|down-regulation of regulated secretory pathway|down regulation of regulated secretory pathway|downregulation of regulated secretory pathway				An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.		pad	2014-08-18T10:05:02Z						biological_process											owl:Class	
GO:1902031	biolink:NamedThing	regulation of NADP metabolic process	Any process that modulates the frequency, rate or extent of NADP metabolic process.	got7fsn_ti	regulation of oxidized NADP metabolism|regulation of NADP metabolism|regulation of nicotinamide adenine dinucleotide phosphate metabolic process|regulation of reduced NADP metabolic process|regulation of NADP (oxidized) metabolism|regulation of reduced nicotinamide adenine dinucleotide phosphate metabolic process|regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolism|regulation of NAD phosphorylation and dephosphorylation|regulation of reduced nicotinamide adenine dinucleotide phosphate metabolism|regulation of oxidized NADP metabolic process|regulation of NADP (reduced) metabolism|regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolic process|regulation of NADP (oxidized) metabolic process|regulation of nicotinamide adenine dinucleotide phosphate metabolism|regulation of reduced NADP metabolism|regulation of NADP (reduced) metabolic process|regulation of NADPH metabolic process|regulation of NADPH metabolism						jl	2013-03-28T20:21:48Z						biological_process											owl:Class	
GO:1990981	biolink:NamedThing	obsolete regulation of protein localization to cell division site involved in cell separation after cytokinesis	OBSOLETE. A regulation of protein localization to cell division site involved in cell separation after cytokinesis.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2016-08-21T19:43:21Z		True				biological_process											owl:Class	
GO:0015883	biolink:NamedThing	FAD transport	The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.	got7fsn_ti	flavin-adenine dinucleotide transport|flavin adenine dinucleotide transport													biological_process											owl:Class	
GO:1990557	biolink:NamedThing	mitochondrial sulfate transmembrane transport	The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:49:35Z						biological_process											owl:Class	
GO:0098526	biolink:NamedThing	inhibitory neuromuscular junction of somatic myotube	A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods.	got7fsn_ti							dos	2013-10-14T12:06:43Z						cellular_component											owl:Class	
GO:0070455	biolink:NamedThing	positive regulation of heme biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.	got7fsn_ti	positive regulation of heme biosynthesis|positive regulation of heme anabolism|positive regulation of heme formation|up-regulation of heme biosynthetic process|positive regulation of heme synthesis|activation of heme biosynthetic process|positive regulation of haem biosynthetic process|up regulation of heme biosynthetic process|stimulation of heme biosynthetic process|upregulation of heme biosynthetic process													biological_process											owl:Class	
GO:1903172	biolink:NamedThing	cellular carbon dioxide homeostasis	Any biological process involved in the maintenance of an internal steady state of carbon dioxide at the level of the cell.	got7fsn_ti							mr	2014-07-11T20:58:30Z						biological_process											owl:Class	
GO:0010104	biolink:NamedThing	regulation of ethylene-activated signaling pathway	Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction.	got7fsn_ti	regulation of ethene mediated signaling pathway|regulation of ethylene mediated signaling pathway|regulation of ethene mediated signalling pathway|regulation of ethylene mediated signalling pathway													biological_process											owl:Class	
GO:0015943	biolink:NamedThing	formate biosynthetic process	The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.	got7fsn_ti	formate synthesis|formic acid biosynthesis|formate biosynthesis|formate anabolism|formate formation|formic acid biosynthetic process													biological_process											owl:Class	
GO:0052242	biolink:NamedThing	obsolete chemotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	chemotaxis within other organism during symbiotic interaction|chemotaxis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1901418	biolink:NamedThing	positive regulation of response to ethanol	Any process that activates or increases the frequency, rate or extent of response to ethanol.	got7fsn_ti	up regulation of response to ethanol|upregulation of response to ethanol|activation of response to ethanol|up-regulation of response to ethanol						tt	2012-10-01T16:49:51Z						biological_process											owl:Class	
GO:1904974	biolink:NamedThing	heparanase complex	A protein complex which is capable of heparanase activity.	got7fsn_ti	HEPS complex				An example of this is HPSE in human (Q9Y251) in PMID:12927802 (inferred from direct assay).		bhm	2016-02-18T11:50:39Z						cellular_component											owl:Class	
GO:0075068	biolink:NamedThing	obsolete growth or development of symbiont in host vascular tissue	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's vascular tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of symbiont in host vascular tissue				This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'development of symbiont in host vascular tissue ; GO:0044122' and 'growth of symbiont in host vascular tissue ; GO:0044123'.	GO:0051701|GO:0044114				True				biological_process											owl:Class	
GO:0042416	biolink:NamedThing	dopamine biosynthetic process	The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	got7fsn_ti	dopamine anabolism|dopamine synthesis|dopamine formation|dopamine biosynthesis													biological_process											owl:Class	
GO:1900971	biolink:NamedThing	regulation of sarcinapterin biosynthetic process	Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process.	got7fsn_ti	regulation of sarcinapterin synthesis|regulation of sarcinapterin formation|regulation of sarcinapterin anabolism|regulation of sarcinapterin biosynthesis						tt	2012-06-14T03:59:44Z						biological_process											owl:Class	
GO:0002913	biolink:NamedThing	positive regulation of lymphocyte anergy	Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.	got7fsn_ti	upregulation of lymphocyte anergy|activation of lymphocyte anergy|stimulation of lymphocyte anergy|up-regulation of lymphocyte anergy|up regulation of lymphocyte anergy													biological_process											owl:Class	
GO:0001316	biolink:NamedThing	obsolete age-dependent response to reactive oxygen species involved in replicative cell aging	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring during the process of replicative cell aging as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.	got7fsn_ti	age-dependent response to reactive oxygen species during replicative cell ageing|age-dependent response to active oxygen species during replicative cell aging|age-dependent response to reactive oxygen species during replicative cell aging|age-dependent response to reactive oxidative species during replicative cell aging|age-dependent response to reactive oxygen intermediate during replicative cell aging|age-dependent response to AOS during replicative cell aging|age-dependent response to ROI during replicative cell aging|age-dependent response to ROS during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0000191	biolink:NamedThing	obsolete activation of MAPKKK (pseudohyphal growth)	OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth.	got7fsn_ti	activation of MAPKKK (pseudohyphal growth)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0018286	biolink:NamedThing	obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide	OBSOLETE. The incorporation of iron into a 3Fe-3S iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide. The three-iron three-sulfur cluster probably does not exist except as an intermediate form.	got7fsn_ti	iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide|iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron trisulphide				This term was made obsolete because the three-iron three-sulfur cluster is now thought not to exist except possibly as an intermediate form.	GO:0018198|GO:0018283				True				biological_process											owl:Class	
GO:1903215	biolink:NamedThing	negative regulation of protein targeting to mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion.	got7fsn_ti	down-regulation of protein import into mitochondrion|down-regulation of protein targeting to mitochondria|downregulation of protein targeting to mitochondria|down regulation of mitochondrial translocation|downregulation of protein-mitochondrial targeting|downregulation of mitochondrial protein import|negative regulation of protein-mitochondrial targeting|inhibition of mitochondrial translocation|down-regulation of protein targeting to mitochondrion|downregulation of protein targeting to mitochondrion|negative regulation of mitochondrial protein import|inhibition of protein import into mitochondrion|down regulation of protein-mitochondrial targeting|down regulation of mitochondrial protein import|inhibition of protein targeting to mitochondrion|inhibition of protein targeting to mitochondria|down-regulation of mitochondrial protein import|inhibition of mitochondrial protein import|negative regulation of mitochondrial translocation|downregulation of mitochondrial translocation|downregulation of protein import into mitochondrion|inhibition of protein-mitochondrial targeting|down regulation of protein targeting to mitochondria|down regulation of protein import into mitochondrion|down regulation of protein targeting to mitochondrion|down-regulation of protein-mitochondrial targeting|negative regulation of protein import into mitochondrion|down-regulation of mitochondrial translocation|negative regulation of protein targeting to mitochondria						bf	2014-07-24T10:17:19Z						biological_process											owl:Class	
GO:1901091	biolink:NamedThing	negative regulation of protein tetramerization	Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization.	got7fsn_ti	down-regulation of protein tetramerization|negative regulation of protein tetramer biosynthesis|negative regulation of protein tetramer formation|down regulation of protein tetramer biosynthetic process|negative regulation of protein tetramer assembly|downregulation of protein tetramerization|down-regulation of protein tetramer assembly|downregulation of protein tetramer biosynthetic process|inhibition of protein tetramer biosynthetic process|downregulation of protein tetramer biosynthesis|inhibition of protein tetramer biosynthesis|downregulation of protein tetramer assembly|down regulation of protein tetramer assembly|inhibition of protein tetramer formation|down-regulation of protein tetramer biosynthetic process|down regulation of protein tetramerization|down regulation of protein tetramer formation|inhibition of protein tetramerization|down regulation of protein tetramer biosynthesis|down-regulation of protein tetramer formation|negative regulation of protein tetramer biosynthetic process|inhibition of protein tetramer assembly|down-regulation of protein tetramer biosynthesis|downregulation of protein tetramer formation						pm	2012-07-06T12:51:24Z						biological_process											owl:Class	
GO:1902371	biolink:NamedThing	negative regulation of tRNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.	got7fsn_ti	down-regulation of tRNA degradation|negative regulation of tRNA catabolism|downregulation of tRNA degradation|inhibition of tRNA catabolic process|down regulation of tRNA catabolic process|inhibition of tRNA degradation|negative regulation of tRNA breakdown|down-regulation of tRNA catabolic process|down regulation of tRNA catabolism|down regulation of tRNA breakdown|inhibition of tRNA breakdown|down-regulation of tRNA catabolism|down-regulation of tRNA breakdown|downregulation of tRNA breakdown|down regulation of tRNA degradation|downregulation of tRNA catabolism|inhibition of tRNA catabolism|negative regulation of tRNA degradation|downregulation of tRNA catabolic process						bf	2013-08-22T15:08:20Z						biological_process											owl:Class	
GO:2000414	biolink:NamedThing	negative regulation of fibronectin-dependent thymocyte migration	Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration.	got7fsn_ti	negative regulation of fibronectin-dependent immature T lymphocyte migration|negative regulation of fibronectin-dependent immature T cell migration|negative regulation of fibronectin-dependent immature T-lymphocyte migration|negative regulation of fibronectin-dependent immature T-cell migration|negative regulation of fibronectin-dependent thymic lymphocyte migration						mah	2011-02-23T01:38:37Z						biological_process											owl:Class	
GO:1904979	biolink:NamedThing	negative regulation of endosome organization	Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization.	got7fsn_ti	inhibition of endosome organization|down-regulation of endosome organisation|down-regulation of endosome organization and biogenesis|negative regulation of endosome organisation|downregulation of endosome organization|down regulation of endosome organization and biogenesis|negative regulation of endosome organization and biogenesis|down regulation of endosome organization|down-regulation of endosome organization|inhibition of endosome organization and biogenesis|downregulation of endosome organization and biogenesis|inhibition of endosome organisation|downregulation of endosome organisation|down regulation of endosome organisation						pad	2016-02-22T19:21:08Z						biological_process											owl:Class	
GO:0046238	biolink:NamedThing	obsolete phthalate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of phthalate, any ester or salt of phthalic acid.	got7fsn_ti	phthalate formation|phthalate anabolism|phthalate synthesis|phthalate biosynthesis|phthalate biosynthetic process			GO:0018963	This term was made obsolete because phthalates are not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0006088	biolink:NamedThing	obsolete acetate to acetyl-CoA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	acetate to acetyl-CoA				This term was made obsolete because it represents a function rather than a process.	GO:0003987				True				biological_process											owl:Class	
GO:1905151	biolink:NamedThing	negative regulation of voltage-gated sodium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity.	got7fsn_ti	down regulation of voltage-sensitive sodium channel|downregulation of voltage-sensitive sodium channel|down regulation of voltage-gated sodium channel activity|negative regulation of voltage-dependent sodium channel activity|down regulation of voltage-dependent sodium channel activity|downregulation of voltage-gated sodium channel activity|inhibition of voltage-sensitive sodium channel|downregulation of voltage-gated sodium ion channel activity|inhibition of voltage-gated sodium ion channel activity|inhibition of voltage gated sodium channel activity|negative regulation of voltage gated sodium channel activity|inhibition of voltage-dependent sodium channel activity|down-regulation of voltage-gated sodium channel activity|negative regulation of voltage-gated sodium ion channel activity|down-regulation of voltage-gated sodium ion channel activity|down-regulation of voltage-sensitive sodium channel|down regulation of voltage-gated sodium ion channel activity|down-regulation of voltage-dependent sodium channel activity|downregulation of voltage-dependent sodium channel activity|down regulation of voltage gated sodium channel activity|negative regulation of voltage-sensitive sodium channel|inhibition of voltage-gated sodium channel activity|downregulation of voltage gated sodium channel activity|down-regulation of voltage gated sodium channel activity						sl	2016-04-15T21:47:49Z						biological_process											owl:Class	
GO:0060466	biolink:NamedThing	activation of meiosis involved in egg activation	Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.	got7fsn_ti	reactivation of meiosis after fertilization|resumption of meiosis involved in egg activation													biological_process											owl:Class	
GO:1903529	biolink:NamedThing	negative regulation of dCDP biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process.	got7fsn_ti	inhibition of dCDP formation|downregulation of dCDP formation|down-regulation of dCDP anabolism|down regulation of dCDP biosynthetic process|down-regulation of dCDP formation|inhibition of dCDP biosynthesis|down regulation of dCDP synthesis|inhibition of dCDP anabolism|downregulation of dCDP anabolism|inhibition of dCDP biosynthetic process|down-regulation of dCDP synthesis|down regulation of dCDP biosynthesis|down regulation of dCDP anabolism|downregulation of dCDP biosynthetic process|down-regulation of dCDP biosynthetic process|down regulation of dCDP formation|negative regulation of dCDP formation|negative regulation of dCDP anabolism|downregulation of dCDP biosynthesis|downregulation of dCDP synthesis|negative regulation of dCDP synthesis|down-regulation of dCDP biosynthesis|negative regulation of dCDP biosynthesis|inhibition of dCDP synthesis						al	2014-10-07T15:01:27Z						biological_process											owl:Class	
GO:0046465	biolink:NamedThing	dolichyl diphosphate metabolic process	The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes.	got7fsn_ti	dolichyl diphosphate metabolism													biological_process											owl:Class	
GO:0042431	biolink:NamedThing	indole metabolic process	The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).	got7fsn_ti	indole metabolism													biological_process											owl:Class	
GO:0043290	biolink:NamedThing	apocarotenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.	got7fsn_ti	apo carotenoid catabolic process|apocarotenoid catabolism|apocarotenoid degradation|apocarotenoid breakdown													biological_process											owl:Class	
GO:0002862	biolink:NamedThing	negative regulation of inflammatory response to antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.	got7fsn_ti	inhibition of inflammatory response to antigenic stimulus|downregulation of inflammatory response to antigenic stimulus|down regulation of inflammatory response to antigenic stimulus|down-regulation of inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:1904130	biolink:NamedThing	regulation of convergent extension involved in neural plate elongation	Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation.	got7fsn_ti							dph	2015-04-10T21:13:21Z						biological_process											owl:Class	
GO:2000739	biolink:NamedThing	regulation of mesenchymal stem cell differentiation	Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation.	got7fsn_ti							yaf	2011-06-14T02:31:27Z						biological_process											owl:Class	
GO:0005322	biolink:NamedThing	obsolete low-density lipoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	low-density lipoprotein|LDL			GO:0005319	This term was made obsolete because it does not represent a molecular function.					True				molecular_function											owl:Class	
GO:1900138	biolink:NamedThing	negative regulation of phospholipase A2 activity	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity.	got7fsn_ti	down regulation of secreted phospholipase A2 activity|negative regulation of phosphatidolipase activity|down-regulation of phosphatidolipase activity|negative regulation of secreted phospholipase A2 activity|downregulation of phosphatidylcholine 2-acylhydrolase activity|down-regulation of phosphatidase activity|downregulation of lecithinase A activity|downregulation of phosphatidolipase activity|negative regulation of cytosolic phospholipase A2 activity|inhibition of lecithinase A activity|down regulation of phosphatidase activity|inhibition of phospholipase A2 activity|down regulation of phosphatidolipase activity|negative regulation of phosphatidylcholine 2-acylhydrolase activity|downregulation of phosphatidase activity|down-regulation of lecithinase A activity|inhibition of phosphatidylcholine 2-acylhydrolase activity|down-regulation of phospholipase A|downregulation of cytosolic phospholipase A2 activity|inhibition of cytosolic phospholipase A2 activity|inhibition of phosphatidolipase activity|down-regulation of secreted phospholipase A2 activity|down-regulation of cytosolic phospholipase A2 activity|inhibition of phosphatidase activity|negative regulation of lecithinase A activity|downregulation of phospholipase A|down regulation of lecithinase A activity|negative regulation of phosphatidase activity|down-regulation of phosphatidylcholine 2-acylhydrolase activity|down regulation of phosphatidylcholine 2-acylhydrolase activity|downregulation of secreted phospholipase A2 activity|inhibition of secreted phospholipase A2 activity|down-regulation of phospholipase A2 activity|down regulation of phospholipase A2 activity|inhibition of phospholipase A|negative regulation of phospholipase A|down regulation of phospholipase A|downregulation of phospholipase A2 activity|down regulation of cytosolic phospholipase A2 activity						rph	2012-03-01T09:18:24Z						biological_process											owl:Class	
GO:1902172	biolink:NamedThing	regulation of keratinocyte apoptotic process	Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.	got7fsn_ti	regulation of keratinocyte apoptosis						rl	2013-05-29T14:36:11Z						biological_process											owl:Class	
GO:0016845	biolink:NamedThing	obsolete other carbon-nitrogen lyase activity	OBSOLETE. Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.	got7fsn_ti	other carbon-nitrogen lyase activity				This term was made obsolete because it was an unnecessary grouping term.	GO:0016840				True				molecular_function											owl:Class	
GO:1905832	biolink:NamedThing	positive regulation of spindle assembly	Any process that activates or increases the frequency, rate or extent of spindle assembly.	got7fsn_ti	positive regulation of bipolar spindle formation|upregulation of spindle biosynthesis|up regulation of bipolar spindle biosynthesis|up regulation of spindle formation|activation of bipolar spindle biosynthesis|positive regulation of bipolar spindle biosynthesis|up-regulation of bipolar spindle formation|up regulation of spindle assembly|up regulation of bipolar spindle formation|positive regulation of spindle formation|upregulation of spindle assembly|up-regulation of spindle biosynthesis|up regulation of spindle biosynthesis|up-regulation of bipolar spindle biosynthesis|upregulation of bipolar spindle formation|activation of spindle biosynthesis|upregulation of bipolar spindle biosynthesis|up-regulation of spindle assembly|positive regulation of spindle biosynthesis|activation of spindle assembly|activation of bipolar spindle formation|activation of spindle formation|up-regulation of spindle formation|upregulation of spindle formation						hbye	2017-01-17T10:26:46Z						biological_process											owl:Class	
GO:0032172	biolink:NamedThing	germ tube septin ring	A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:1903490	biolink:NamedThing	positive regulation of mitotic cytokinesis	Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis.	got7fsn_ti	up regulation of mitotic cytokinesis|activation of mitotic cytokinesis|positive regulation of cytokinesis after mitosis|up-regulation of cytokinesis after mitosis|up-regulation of mitotic cytokinesis|up regulation of cytokinesis after mitosis|activation of cytokinesis after mitosis|upregulation of mitotic cytokinesis|upregulation of cytokinesis after mitosis						al	2014-09-25T09:00:35Z						biological_process											owl:Class	
GO:0071416	biolink:NamedThing	cellular response to tropane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.	got7fsn_ti							mah	2009-12-14T03:12:24Z						biological_process											owl:Class	
GO:0015655	biolink:NamedThing	alanine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in).	got7fsn_ti	sodium:alanine symporter activity						jl	2012-08-08T12:57:30Z			GO:0044670	RHEA:29283		molecular_function											owl:Class	
GO:1903301	biolink:NamedThing	positive regulation of hexokinase activity	Any process that activates or increases the frequency, rate or extent of hexokinase activity.	got7fsn_ti	up regulation of ATP:D-hexose 6-phosphotransferase activity|up-regulation of hexokinase type IV (glucokinase) activity|up-regulation of hexokinase activity|upregulation of hexokinase (phosphorylating)|up-regulation of hexokinase type IV|upregulation of glucose ATP phosphotransferase activity|upregulation of ATP:D-hexose 6-phosphotransferase activity|up-regulation of ATP-dependent hexokinase activity|activation of ATP:D-hexose 6-phosphotransferase activity|up-regulation of hexokinase type IV glucokinase activity|positive regulation of hexokinase D|up regulation of ATP-dependent hexokinase activity|upregulation of ATP-dependent hexokinase activity|up regulation of hexokinase type I activity|upregulation of hexokinase activity|up-regulation of glucose ATP phosphotransferase activity|up regulation of hexokinase type IV (glucokinase) activity|positive regulation of hexokinase type IV glucokinase activity|positive regulation of hexokinase type III activity|activation of hexokinase type III activity|upregulation of hexokinase D|up-regulation of ATP:D-hexose 6-phosphotransferase activity|positive regulation of ATP-dependent hexokinase activity|upregulation of hexokinase type I activity|positive regulation of glucose ATP phosphotransferase activity|up regulation of hexokinase type II activity|positive regulation of hexokinase (phosphorylating)|up-regulation of hexokinase D|activation of hexokinase type I activity|positive regulation of ATP:D-hexose 6-phosphotransferase activity|up regulation of hexokinase type III activity|up-regulation of hexokinase (phosphorylating)|upregulation of hexokinase type IV (glucokinase) activity|activation of ATP-dependent hexokinase activity|up-regulation of hexokinase type III activity|up-regulation of hexokinase type II activity|up regulation of glucose ATP phosphotransferase activity|upregulation of hexokinase type IV|activation of hexokinase D|activation of hexokinase (phosphorylating)|activation of hexokinase type II activity|upregulation of hexokinase type III activity|up-regulation of hexokinase type I activity|activation of hexokinase activity|upregulation of hexokinase type II activity|up regulation of hexokinase (phosphorylating)|positive regulation of hexokinase type IV (glucokinase) activity|activation of hexokinase type IV|up regulation of hexokinase type IV|positive regulation of hexokinase type I activity|up regulation of hexokinase activity|activation of glucose ATP phosphotransferase activity|activation of hexokinase type IV glucokinase activity|up regulation of hexokinase type IV glucokinase activity|activation of hexokinase type IV (glucokinase) activity|up regulation of hexokinase D|positive regulation of hexokinase type II activity|upregulation of hexokinase type IV glucokinase activity|positive regulation of hexokinase type IV						mr	2014-08-15T23:18:09Z						biological_process											owl:Class	
GO:0009708	biolink:NamedThing	benzyl isoquinoline alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.	got7fsn_ti	benzyl isoquinoline alkaloid formation|benzyl isoquinoline alkaloid anabolism|benzyl isoquinoline alkaloid synthesis|benzyl isoquinoline alkaloid biosynthesis													biological_process											owl:Class	
GO:0062062	biolink:NamedThing	oligosaccharyltransferase complex binding	Binding to an oligosaccharyltransferase complex.	got7fsn_ti							dph	2018-08-31T13:56:32Z						molecular_function											owl:Class	
GO:0097080	biolink:NamedThing	plasma membrane selenite transport	The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane.	got7fsn_ti	plasma membrane hydrogenselenite transport						pr	2011-06-17T10:03:55Z						biological_process											owl:Class	
GO:1901586	biolink:NamedThing	negative regulation of acid-sensing ion channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity.	got7fsn_ti	inhibition of acid-sensing ion channel activity|down-regulation of ASIC activity|downregulation of acid-sensing ion channel activity|down-regulation of acid-sensing ion channel activity|negative regulation of ASIC activity|downregulation of ASIC activity|inhibition of ASIC activity|down regulation of ASIC activity|down regulation of acid-sensing ion channel activity						jl	2012-11-07T13:37:32Z						biological_process											owl:Class	
GO:0045965	biolink:NamedThing	negative regulation of ecdysteroid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids.	got7fsn_ti	negative regulation of ecdysteroid metabolism|inhibition of ecdysteroid metabolic process|down regulation of ecdysteroid metabolic process|downregulation of ecdysteroid metabolic process|down-regulation of ecdysteroid metabolic process													biological_process											owl:Class	
GO:0051182	biolink:NamedThing	obsolete coenzyme transport	OBSOLETE. The directed movement of a coenzyme into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	got7fsn_ti					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a coenzyme.					True				biological_process											owl:Class	
CHEBI:35194	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900374	biolink:NamedThing	obsolete positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching.	got7fsn_ti	up regulation of mating type switching by regulation of transcription from RNA polymerase II promoter|up-regulation of mating type switching by regulation of transcription from RNA polymerase II promoter|stimulation of mating type switching by regulation of transcription from RNA polymerase II promoter|upregulation of mating type switching by regulation of transcription from RNA polymerase II promoter|activation of mating type switching by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-17T12:39:56Z		True				biological_process											owl:Class	
GO:1904499	biolink:NamedThing	obsolete regulation of chromatin-mediated maintenance of transcription	OBSOLETE. Any process that modulates the frequency, rate or extent of chromatin-mediated maintenance of transcription.	got7fsn_ti					This term was obsoleted because it represents a readout.		nc	2015-07-24T09:31:08Z		True				biological_process											owl:Class	
GO:1905670	biolink:NamedThing	TORC2 complex disassembly	The disaggregation of a TORC2 complex into its constituent components.	got7fsn_ti	TORC2 disassembly|TORC 2 complex disassembly|mTORC2 disassembly|rapamycin and nutrient-insensitive TOR complex disassembly|TOR complex 2 disassembly						kmv	2016-11-11T21:03:37Z						biological_process											owl:Class	
GO:0099614	biolink:NamedThing	protein localization to spore cell wall	A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall.	got7fsn_ti	protein targeting to spore cell wall													biological_process											owl:Class	
GO:0015444	biolink:NamedThing	P-type magnesium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in).	got7fsn_ti	magnesium transmembrane transporter activity, phosphorylative mechanism|Mg(2+)-importing ATPase activity|magnesium importing ATPase activity|magnesium-translocating P-type ATPase activity|Mg2+-importing ATPase activity|ATP phosphohydrolase (Mg2+-importing)											EC:7.2.2.14|RHEA:10260|MetaCyc:3.6.3.2-RXN		molecular_function											owl:Class	
GO:0019302	biolink:NamedThing	D-ribose biosynthetic process	The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).	got7fsn_ti	D-ribose synthesis|D-ribose biosynthesis|D-ribose anabolism|D-ribose formation													biological_process											owl:Class	
GO:1901534	biolink:NamedThing	positive regulation of hematopoietic progenitor cell differentiation	Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.	got7fsn_ti	up regulation of haemopoietic progenitor cell differentiation|activation of hematopoietic progenitor cell differentiation|positive regulation of haematopoietic progenitor cell differentiation|positive regulation of hemopoietic progenitor cell differentiation|up regulation of hematopoietic progenitor cell differentiation|up-regulation of hematopoietic progenitor cell differentiation|activation of haematopoietic progenitor cell differentiation|upregulation of haemopoietic progenitor cell differentiation|up-regulation of haemopoietic progenitor cell differentiation|activation of haemopoietic progenitor cell differentiation|upregulation of hematopoietic progenitor cell differentiation|up regulation of haematopoietic progenitor cell differentiation|up-regulation of haematopoietic progenitor cell differentiation|activation of hemopoietic progenitor cell differentiation|positive regulation of haemopoietic progenitor cell differentiation|up regulation of hemopoietic progenitor cell differentiation|up-regulation of hemopoietic progenitor cell differentiation|upregulation of haematopoietic progenitor cell differentiation|upregulation of hemopoietic progenitor cell differentiation						vk	2012-10-24T11:23:14Z						biological_process											owl:Class	
GO:1904580	biolink:NamedThing	regulation of intracellular mRNA localization	Any process that modulates the frequency, rate or extent of intracellular mRNA localization.	got7fsn_ti	regulation of establishment and maintenance of intracellular RNA localization|regulation of intracellular mRNA positioning|regulation of intracellular mRNA localisation|regulation of mRNA positioning, intracellular|regulation of mRNA localization, intracellular						sl	2015-08-19T23:40:25Z						biological_process											owl:Class	
GO:1903216	biolink:NamedThing	regulation of protein processing involved in protein targeting to mitochondrion	Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion.	got7fsn_ti	regulation of mitochondrial processing|regulation of mitochondrial protein processing during import						bf	2014-07-24T10:20:54Z						biological_process											owl:Class	
GO:0097092	biolink:NamedThing	polyacyltrehalose metabolic process	The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.	got7fsn_ti	polyacyltrehalose metabolism						pr	2011-07-05T01:58:28Z						biological_process											owl:Class	
CHEBI:57984	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031112	biolink:NamedThing	positive regulation of microtubule polymerization or depolymerization	Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.	got7fsn_ti	stimulation of microtubule polymerization or depolymerization|activation of microtubule polymerization or depolymerization|up-regulation of microtubule polymerization or depolymerization|upregulation of microtubule polymerization or depolymerization|up regulation of microtubule polymerization or depolymerization													biological_process											owl:Class	
CL:1000073	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901439	biolink:NamedThing	positive regulation of toluene metabolic process	Any process that activates or increases the frequency, rate or extent of toluene metabolic process.	got7fsn_ti	upregulation of toluene metabolism|activation of methylbenzene metabolic process|up-regulation of toluene metabolism|up-regulation of methylbenzene metabolism|activation of toluene metabolic process|positive regulation of methylbenzene metabolism|up regulation of methylbenzene metabolic process|upregulation of toluene metabolic process|upregulation of methylbenzene metabolism|upregulation of methylbenzene metabolic process|positive regulation of toluene metabolism|activation of toluene metabolism|up regulation of toluene metabolism|up regulation of toluene metabolic process|up regulation of methylbenzene metabolism|up-regulation of toluene metabolic process|activation of methylbenzene metabolism|positive regulation of methylbenzene metabolic process|up-regulation of methylbenzene metabolic process						tt	2012-10-01T21:19:08Z						biological_process											owl:Class	
GO:0007317	biolink:NamedThing	regulation of pole plasm oskar mRNA localization	Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.	got7fsn_ti	regulation of oocyte pole plasm oskar mRNA localization|regulation of pole plasm oskar mRNA localisation													biological_process											owl:Class	
GO:0019586	biolink:NamedThing	galacturonate metabolic process	The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	got7fsn_ti	galacturonate metabolism													biological_process											owl:Class	
GO:0080119	biolink:NamedThing	ER body organization	A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.	got7fsn_ti	endoplasmic reticulum body organization|ER body organisation|ER body organization and biogenesis|endoplasmic reticulum body organization and biogenesis						dhl	2009-04-27T04:01:26Z						biological_process											owl:Class	
GO:1904788	biolink:NamedThing	obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion.	got7fsn_ti	positive regulation of induction of conjugation with cellular fusion by regulation of global transcription from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by regulation of transcription from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter, global|positive regulation of induction of conjugation with cellular fusion by regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of induction of conjugation with cellular fusion by global transcription regulation from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		tb	2015-11-04T21:17:08Z		True				biological_process											owl:Class	
GO:0019441	biolink:NamedThing	tryptophan catabolic process to kynurenine	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.	got7fsn_ti	tryptophan degradation to kynurenine|tryptophan breakdown to kynurenine											MetaCyc:TRPKYNCAT-PWY		biological_process											owl:Class	
GO:1903122	biolink:NamedThing	negative regulation of TRAIL-activated apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.	got7fsn_ti	down-regulation of TRAIL-activated apoptotic signaling pathway|inhibition of TRAIL-activated apoptotic signaling pathway|down regulation of TRAIL-activated extrinsic apoptotic signaling pathway|downregulation of TRAIL-induced apoptotic signaling pathway|downregulation of TRAIL-activated apoptotic signaling pathway|downregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|inhibition of TRAIL-activated extrinsic apoptotic signaling pathway|inhibition of TRAIL-induced apoptotic signaling pathway|negative regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|negative regulation of TRAIL-induced apoptotic signaling pathway|down-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|down-regulation of TRAIL-induced apoptotic signaling pathway|downregulation of TRAIL-activated extrinsic apoptotic signaling pathway|down-regulation of TRAIL-activated extrinsic apoptotic signaling pathway|inhibition of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|down regulation of TRAIL-activated apoptotic signaling pathway|down regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|negative regulation of TRAIL-activated extrinsic apoptotic signaling pathway|down regulation of TRAIL-induced apoptotic signaling pathway						bf	2014-06-17T12:39:21Z						biological_process											owl:Class	
GO:2000578	biolink:NamedThing	obsolete negative regulation of microtubule motor activity, minus-end-directed	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.	got7fsn_ti	negative regulation of ATP-dependent microtubule motor activity, minus-end-directed|negative regulation of minus-end-directed microtubule motor activity|negative regulation of minus-end-directed kinesin ATPase activity|negative regulation of kinesin ATP phosphohydrolase (minus-end-directed)	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140661	bf	2011-04-05T08:37:57Z		True				biological_process											owl:Class	
GO:0071538	biolink:NamedThing	obsolete SH2 domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an SH2 domain interaction.	got7fsn_ti					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T03:46:16Z		True				biological_process											owl:Class	
GO:1904407	biolink:NamedThing	positive regulation of nitric oxide metabolic process	Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process.	got7fsn_ti	upregulation of nitric oxide metabolic process|up-regulation of nitric oxide metabolic process|positive regulation of nitric oxide metabolism|up regulation of nitric oxide metabolism|activation of nitric oxide metabolism|up regulation of nitric oxide metabolic process|up-regulation of nitric oxide metabolism|upregulation of nitric oxide metabolism|activation of nitric oxide metabolic process						sl	2015-06-24T20:56:47Z						biological_process											owl:Class	
GO:0043499	biolink:NamedThing	obsolete eukaryotic cell surface binding	OBSOLETE. Binding to a component on the surface of a eukaryotic cell.	got7fsn_ti	eukaryotic cell surface binding				This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term.	GO:0046812|GO:0006952|GO:0009986|GO:0005102|GO:0003823				True				molecular_function											owl:Class	
GO:0070564	biolink:NamedThing	positive regulation of vitamin D receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.	got7fsn_ti	up-regulation of vitamin D receptor signaling pathway|up regulation of vitamin D receptor signaling pathway|positive regulation of VDR signaling pathway|activation of vitamin D receptor signaling pathway|upregulation of vitamin D receptor signaling pathway|positive regulation of vitamin D receptor signalling pathway|stimulation of vitamin D receptor signaling pathway						mah	2009-04-14T02:02:54Z						biological_process											owl:Class	
GO:1904503	biolink:NamedThing	negative regulation of lipophagy	Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy.	got7fsn_ti	inhibition of lipophagy|down regulation of lipophagy|down-regulation of lipophagy|downregulation of lipophagy						dph	2015-07-24T11:37:18Z						biological_process											owl:Class	
GO:0071401	biolink:NamedThing	cellular response to triglyceride	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.	got7fsn_ti	cellular response to triacylglycerol|cellular response to triacylglyceride						mah	2009-12-11T04:40:56Z						biological_process											owl:Class	
GO:0004262	biolink:NamedThing	obsolete cerevisin activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, and of BZ-Arg-OET > Ac-Tyr-OET. Does not hydrolyze peptide amides.	got7fsn_ti	brewer's yeast proteinase|yeast proteinase B activity|baker's yeast proteinase B|peptidase beta|cerevisin activity|proteinase yscB activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0140009	biolink:NamedThing	L-aspartate import across plasma membrane	The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2017-03-13T10:59:51Z						biological_process											owl:Class	
GO:1902844	biolink:NamedThing	positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway	A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation.	got7fsn_ti	up-regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|positive regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|upregulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|activation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|upregulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|up-regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|up regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|activation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway						mr	2014-04-01T15:28:30Z						biological_process											owl:Class	
GO:0019515	biolink:NamedThing	lactose catabolic process via UDP-galactose	The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose.	got7fsn_ti	lactose breakdown via UDP-galactose|lactose degradation via UDP-galactose													biological_process											owl:Class	
GO:1900201	biolink:NamedThing	obsolete regulation of spread of virus in host, cell to cell	OBSOLETE. Any process that modulates the frequency, rate or extent of spread of virus in host, cell to cell.	got7fsn_ti	regulation of viral spread within host, cell to cell|regulation of spread of virus within host, cell to cell|regulation of cell to cell spread of virus within host|regulation of spread of virus in host, cell to cell				This term was obsoleted at the TermGenie Gatekeeper stage.		pm	2012-03-21T01:15:41Z		True				biological_process											owl:Class	
GO:1902339	biolink:NamedThing	positive regulation of apoptotic process involved in morphogenesis	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.	got7fsn_ti	positive regulation of apoptosis involved in development|up regulation of apoptosis involved in morphogenesis|up regulation of apoptosis involved in development|activation of apoptotic process involved in morphogenesis|positive regulation of morphogenetic apoptosis|up-regulation of morphogenetic apoptosis|upregulation of apoptosis involved in development|up regulation of apoptotic process involved in morphogenesis|up-regulation of apoptosis involved in morphogenesis|upregulation of apoptotic process involved in morphogenesis|upregulation of morphogenetic apoptosis|activation of apoptosis involved in development|up-regulation of apoptosis involved in development|activation of apoptosis involved in morphogenesis|activation of morphogenetic apoptosis|positive regulation of apoptosis involved in morphogenesis|up-regulation of apoptotic process involved in morphogenesis|upregulation of apoptosis involved in morphogenesis|up regulation of morphogenetic apoptosis						sart	2013-07-29T15:03:33Z						biological_process											owl:Class	
GO:1903589	biolink:NamedThing	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.	got7fsn_ti	up-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|up regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|upregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|up regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|activation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|upregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|activation of blood vessel endothelial cell proliferation during sprouting angiogenesis|up-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|positive regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis						pga	2014-11-04T11:39:47Z						biological_process											owl:Class	
GO:0052323	biolink:NamedThing	negative regulation of phytoalexin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.	got7fsn_ti	down regulation of phytoalexin biosynthesis|inhibition of phytoalexin biosynthesis|negative regulation of phytoalexin biosynthesis|down-regulation of phytoalexin biosynthesis|downregulation of phytoalexin biosynthesis													biological_process											owl:Class	
GO:1904692	biolink:NamedThing	positive regulation of type B pancreatic cell proliferation	Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation.	got7fsn_ti	activation of pancreatic beta cell proliferation|activation of type B pancreatic cell proliferation|up regulation of type B pancreatic cell proliferation|upregulation of type B pancreatic cell proliferation|up-regulation of pancreatic B cell proliferation|upregulation of pancreatic beta cell proliferation|up regulation of pancreatic B cell proliferation|positive regulation of pancreatic beta cell proliferation|up-regulation of type B pancreatic cell proliferation|activation of pancreatic B cell proliferation|positive regulation of pancreatic B cell proliferation|up-regulation of pancreatic beta cell proliferation|upregulation of pancreatic B cell proliferation|up regulation of pancreatic beta cell proliferation						sl	2015-09-25T15:23:44Z						biological_process											owl:Class	
GO:0042455	biolink:NamedThing	ribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	ribonucleoside anabolism|ribonucleoside formation|ribonucleoside biosynthesis|ribonucleoside synthesis													biological_process											owl:Class	
GO:1902227	biolink:NamedThing	negative regulation of macrophage colony-stimulating factor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.	got7fsn_ti	down-regulation of macrophage colony-stimulating factor signalling pathway|down regulation of macrophage colony-stimulating factor signalling pathway|inhibition of macrophage colony-stimulating factor signalling pathway|downregulation of macrophage colony-stimulating factor signaling pathway|inhibition of macrophage colony-stimulating factor signaling pathway|negative regulation of M-CSF signaling pathway|down-regulation of macrophage colony-stimulating factor signaling pathway|downregulation of macrophage colony-stimulating factor signalling pathway|downregulation of M-CSF signaling pathway|down-regulation of M-CSF signaling pathway|negative regulation of macrophage colony-stimulating factor signalling pathway|down regulation of M-CSF signaling pathway|inhibition of M-CSF signaling pathway|down regulation of macrophage colony-stimulating factor signaling pathway						lb	2013-06-14T06:28:54Z						biological_process											owl:Class	
GO:1904510	biolink:NamedThing	positive regulation of protein localization to basolateral plasma membrane	Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane.	got7fsn_ti	upregulation of protein localization to basolateral plasma membrane|upregulation of protein localisation to basolateral plasma membrane|up regulation of protein localisation in basolateral plasma membrane|up-regulation of protein localization to basolateral plasma membrane|positive regulation of protein localisation in basolateral plasma membrane|positive regulation of protein localization in basolateral plasma membrane|up regulation of protein localisation to basolateral plasma membrane|up regulation of protein localization in basolateral plasma membrane|up-regulation of protein localisation to basolateral plasma membrane|activation of protein localisation in basolateral plasma membrane|upregulation of protein localisation in basolateral plasma membrane|up regulation of protein localization to basolateral plasma membrane|positive regulation of protein localisation to basolateral plasma membrane|activation of protein localization to basolateral plasma membrane|up-regulation of protein localization in basolateral plasma membrane|activation of protein localisation to basolateral plasma membrane|up-regulation of protein localisation in basolateral plasma membrane|upregulation of protein localization in basolateral plasma membrane|activation of protein localization in basolateral plasma membrane						kmv	2015-07-24T17:56:38Z						biological_process											owl:Class	
GO:1901872	biolink:NamedThing	ecgonone methyl ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ecgonone methyl ester.	got7fsn_ti	ecgonone methyl ester formation|ecgonone methyl ester biosynthesis|ecgonone methyl ester synthesis|ecgonone methyl ester anabolism						ms	2013-02-04T11:58:39Z						biological_process											owl:Class	
GO:0042481	biolink:NamedThing	regulation of odontogenesis	Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.	got7fsn_ti	regulation of odontogenesis of calcareous or chitinous tooth|regulation of tooth development										GO:0042484			biological_process											owl:Class	
GO:2000968	biolink:NamedThing	positive regulation of cell wall polysaccharide catabolic process	Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process.	got7fsn_ti	positive regulation of cell wall polysaccharide breakdown						tt	2011-08-01T02:30:37Z						biological_process											owl:Class	
GO:2000205	biolink:NamedThing	positive regulation of ribosomal large subunit export from nucleus	Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.	got7fsn_ti	positive regulation of ribosomal large subunit export from cell nucleus|positive regulation of ribosomal large subunit transport from nucleus to cytoplasm|positive regulation of 60S ribosomal subunit export from nucleus|positive regulation of 50S ribosomal subunit export from nucleus|positive regulation of ribosomal large subunit-nucleus export|positive regulation of ribosomal large subunit export out of nucleus						mah	2010-10-26T10:52:42Z						biological_process											owl:Class	
GO:1903664	biolink:NamedThing	regulation of asexual reproduction	Any process that modulates the frequency, rate or extent of asexual reproduction.	got7fsn_ti							pf	2014-11-26T21:13:24Z						biological_process											owl:Class	
GO:0110132	biolink:NamedThing	regulation of CRISPR-cas system	Any process that modulates the frequency, rate or extent of a CRISPR-cas system.	got7fsn_ti							kmv	2018-11-14T17:13:16Z						biological_process											owl:Class	
GO:1904022	biolink:NamedThing	positive regulation of G protein-coupled receptor internalization	Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization.	got7fsn_ti	up-regulation of G-protein coupled receptor internalization|activation of G-protein coupled receptor internalization|positive regulation of G-protein coupled receptor internalization|upregulation of G-protein coupled receptor internalization|up regulation of G-protein coupled receptor internalization						pga	2015-03-10T17:10:56Z						biological_process											owl:Class	
GO:2000714	biolink:NamedThing	positive regulation of maintenance of meiotic sister chromatid cohesion, arms	Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.	got7fsn_ti	positive regulation of maintenance of meiotic sister chromatin cohesion along arms|positive regulation of maintenance of sister chromatin cohesion along arms at meiosis I						mah	2011-06-01T12:45:42Z						biological_process											owl:Class	
GO:0016988	biolink:NamedThing	obsolete transcription initiation factor antagonist activity	OBSOLETE. The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity.	got7fsn_ti	transcription initiation factor antagonist activity|transcriptional initiation factor antagonist activity				This term was obsoleted because its definition was vague and apparently broader in scope than the name of the term suggested it was intended to be.					True				molecular_function											owl:Class	
GO:1905192	biolink:NamedThing	regulation of chloroplast fission	Any process that modulates the frequency, rate or extent of chloroplast fission.	got7fsn_ti	regulation of chloroplast division				Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments.		lr	2016-05-10T19:07:34Z						biological_process											owl:Class	
GO:0071930	biolink:NamedThing	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle						mah	2010-09-29T11:12:11Z						biological_process											owl:Class	
GO:1905281	biolink:NamedThing	positive regulation of retrograde transport, endosome to Golgi	Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi.	got7fsn_ti	up-regulation of retrograde (endosome to Golgi) transport|upregulation of retrograde (endosome to Golgi) transport|activation of retrograde (endosome to Golgi) transport|up regulation of retrograde transport, endosome to Golgi|activation of retrograde transport, endosome to Golgi|upregulation of retrograde transport, endosome to Golgi|up-regulation of retrograde transport, endosome to Golgi|positive regulation of retrograde (endosome to Golgi) transport|up regulation of retrograde (endosome to Golgi) transport						bf	2016-06-20T12:25:44Z						biological_process											owl:Class	
GO:1904764	biolink:NamedThing	chaperone-mediated autophagy translocation complex disassembly	The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components.	got7fsn_ti	CMA receptor complex disassembly|CMA translocation complex disassembly|chaperone-mediated autophagy receptor complex disassembly						pad	2015-10-26T16:34:36Z						biological_process											owl:Class	
GO:1905020	biolink:NamedThing	positive regulation of methionine-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity.	got7fsn_ti	positive regulation of L-methionine:tRNAMet ligase (AMP-forming)|positive regulation of methionyl-transfer ribonucleate synthetase activity|up-regulation of methionine-tRNA ligase activity|activation of MetRS activity|positive regulation of methionine translase activity|up-regulation of L-methionine:tRNAMet ligase (AMP-forming)|upregulation of methionine translase activity|up regulation of methionine translase activity|up-regulation of methionyl-transfer ribonucleate synthetase activity|positive regulation of MetRS activity|upregulation of L-methionine:tRNAMet ligase (AMP-forming)|up regulation of methionyl-transfer RNA synthetase activity|upregulation of methionyl-transfer ribonucleate synthetase activity|upregulation of methionine-tRNA ligase activity|up regulation of methionine-tRNA ligase activity|activation of methionyl-tRNA synthetase activity|up regulation of L-methionine:tRNAMet ligase (AMP-forming)|up-regulation of methionyl-tRNA synthetase activity|up-regulation of methionyl-transfer ribonucleic acid synthetase activity|up-regulation of methionine translase activity|up-regulation of MetRS activity|upregulation of methionyl-tRNA synthetase activity|up regulation of methionyl-transfer ribonucleate synthetase activity|positive regulation of methionyl-transfer RNA synthetase activity|up regulation of methionyl-transfer ribonucleic acid synthetase activity|activation of methionyl-transfer ribonucleic acid synthetase activity|activation of methionine-tRNA ligase activity|activation of methionyl-transfer RNA synthetase activity|positive regulation of methionyl-tRNA synthetase activity|up regulation of MetRS activity|up regulation of methionyl-tRNA synthetase activity|activation of methionyl-transfer ribonucleate synthetase activity|upregulation of MetRS activity|activation of L-methionine:tRNAMet ligase (AMP-forming)|positive regulation of methionyl-transfer ribonucleic acid synthetase activity|upregulation of methionyl-transfer ribonucleic acid synthetase activity|activation of methionine translase activity|up-regulation of methionyl-transfer RNA synthetase activity|upregulation of methionyl-transfer RNA synthetase activity						sl	2016-03-03T19:02:57Z						biological_process											owl:Class	
GO:0006171	biolink:NamedThing	cAMP biosynthetic process	The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	3',5' cAMP biosynthetic process|cAMP formation|cAMP synthesis|cyclic AMP biosynthesis|adenosine 3',5'-cyclophosphate biosynthetic process|3',5' cAMP biosynthesis|cAMP anabolism|cyclic AMP biosynthetic process|3',5'-cAMP biosynthetic process|adenosine 3',5'-cyclophosphate biosynthesis|cAMP biosynthesis|3',5'-cAMP biosynthesis													biological_process											owl:Class	
GO:1900679	biolink:NamedThing	negative regulation of ferricrocin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process.	got7fsn_ti	down regulation of ferricrocin formation|down-regulation of ferricrocin synthesis|negative regulation of ferricrocin formation|down-regulation of ferricrocin biosynthetic process|down regulation of ferricrocin anabolism|inhibition of ferricrocin synthesis|down-regulation of ferricrocin biosynthetic process, peptide formation|downregulation of ferricrocin biosynthetic process, peptide modification|negative regulation of ferricrocin synthesis|downregulation of ferricrocin synthesis|down-regulation of ferricrocin anabolism|downregulation of ferricrocin formation|downregulation of ferricrocin biosynthetic process|down regulation of ferricrocin biosynthetic process|down regulation of ferricrocin biosynthetic process, peptide modification|down regulation of ferricrocin biosynthesis|inhibition of ferricrocin biosynthetic process|inhibition of ferricrocin biosynthetic process, peptide formation|downregulation of ferricrocin anabolism|inhibition of ferricrocin biosynthetic process, peptide modification|negative regulation of ferricrocin biosynthetic process, peptide formation|down-regulation of ferricrocin biosynthesis|down-regulation of ferricrocin formation|inhibition of ferricrocin formation|downregulation of ferricrocin biosynthesis|down-regulation of ferricrocin biosynthetic process, peptide modification|negative regulation of ferricrocin biosynthetic process, peptide modification|inhibition of ferricrocin anabolism|negative regulation of ferricrocin biosynthesis|downregulation of ferricrocin biosynthetic process, peptide formation|down regulation of ferricrocin synthesis|inhibition of ferricrocin biosynthesis|negative regulation of ferricrocin anabolism|down regulation of ferricrocin biosynthetic process, peptide formation						di	2012-05-22T04:28:15Z						biological_process											owl:Class	
GO:1901071	biolink:NamedThing	glucosamine-containing compound metabolic process	The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines).	got7fsn_ti	glucosamines metabolism|glucosamines metabolic process|glucosamine-containing compound metabolism						bf	2012-07-02T03:18:04Z						biological_process											owl:Class	
GO:0003900	biolink:NamedThing	obsolete DNA-directed RNA polymerase I activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).	got7fsn_ti	DNA-directed RNA polymerase I activity			GO:0003899	This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase I complex ; GO:0005736'.					True				molecular_function											owl:Class	
GO:0046024	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III that occurs during the mitotic cell cycle.	got7fsn_ti	stimulation of transcription from RNA polymerase III promoter during mitosis|up regulation of transcription from RNA polymerase III promoter during mitosis|positive regulation of transcription from Pol III promoter during mitosis|positive regulation of transcription from RNA polymerase III promoter, mitotic|mitotic activation of transcription from Pol III promoter|activation of transcription from RNA polymerase III promoter during mitosis|up-regulation of transcription from RNA polymerase III promoter during mitosis|upregulation of transcription from RNA polymerase III promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0045945|GO:0044772				True				biological_process											owl:Class	
GO:0110089	biolink:NamedThing	regulation of hippocampal neuron apoptotic process	Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.	got7fsn_ti							kmv	2018-02-13T21:18:29Z						biological_process											owl:Class	
GO:1905407	biolink:NamedThing	regulation of creatine transmembrane transporter activity	Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity.	got7fsn_ti							bc	2016-08-25T15:08:48Z						biological_process											owl:Class	
GO:1902365	biolink:NamedThing	positive regulation of protein localization to spindle pole body	Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body.	got7fsn_ti	positive regulation of protein localisation to spindle pole body|activation of protein localisation to spindle pole body|up-regulation of protein localisation to spindle pole body|up regulation of protein localisation to spindle pole body|upregulation of protein localisation to spindle pole body|up regulation of protein localization to spindle pole body|up-regulation of protein localization to spindle pole body|activation of protein localization to spindle pole body|upregulation of protein localization to spindle pole body						vw	2013-08-15T16:38:31Z						biological_process											owl:Class	
GO:1905387	biolink:NamedThing	response to beta-carotene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.	got7fsn_ti	response to beta,beta-carotene						sl	2016-08-18T16:18:24Z						biological_process											owl:Class	
GO:1903872	biolink:NamedThing	regulation of DNA recombinase mediator complex assembly	Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly.	got7fsn_ti	regulation of DNA recombinase mediator complex formation						rb	2015-02-05T23:36:45Z						biological_process											owl:Class	
GO:0060852	biolink:NamedThing	obsolete regulation of transcription involved in venous endothelial cell fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate and contributes to a cell adopting a venous endothelial cell fate.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0060845|GO:0006357	dph	2009-08-12T11:49:49Z		True				biological_process											owl:Class	
GO:0046059	biolink:NamedThing	dAMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).	got7fsn_ti	dAMP breakdown|dAMP catabolism|dAMP degradation													biological_process											owl:Class	
OBO:OBA_0000011	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902905	biolink:NamedThing	positive regulation of supramolecular fiber organization	Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.	got7fsn_ti	up regulation of fibril organisation|up-regulation of fibril organisation|upregulation of fibril organisation|activation of fibril organisation|positive regulation of fibril organisation|up regulation of fibril organization|upregulation of fibril organization|activation of fibril organization|up-regulation of fibril organization				HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro		rl	2014-04-15T16:46:48Z						biological_process											owl:Class	
GO:0006185	biolink:NamedThing	dGDP biosynthetic process	The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).	got7fsn_ti	dGDP synthesis|dGDP biosynthesis|dGDP anabolism|dGDP formation													biological_process											owl:Class	
GO:1903102	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.	got7fsn_ti	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthesis|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate synthesis|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate anabolism|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate formation						bhm	2014-06-04T14:14:36Z						biological_process											owl:Class	
GO:1902916	biolink:NamedThing	positive regulation of protein polyubiquitination	Any process that activates or increases the frequency, rate or extent of protein polyubiquitination.	got7fsn_ti	upregulation of protein polyubiquitylation|activation of protein polyubiquitination|up regulation of polyubiquitin|upregulation of polyubiquitin|positive regulation of polyubiquitin|up regulation of protein polyubiquitination|upregulation of protein polyubiquitination|positive regulation of protein polyubiquitylation|activation of polyubiquitin|activation of protein polyubiquitinylation|up-regulation of protein polyubiquitination|upregulation of protein polyubiquitinylation|up regulation of protein polyubiquitinylation|up-regulation of protein polyubiquitylation|positive regulation of protein polyubiquitinylation|activation of protein polyubiquitylation|up-regulation of polyubiquitin|up-regulation of protein polyubiquitinylation|up regulation of protein polyubiquitylation						di	2014-04-18T22:10:04Z						biological_process											owl:Class	
GO:0042104	biolink:NamedThing	positive regulation of activated T cell proliferation	Any process that activates or increases the rate or extent of activated T cell proliferation.	got7fsn_ti	positive regulation of activated T-cell proliferation|upregulation of activated T cell proliferation|up-regulation of activated T cell proliferation|positive regulation of activated T lymphocyte proliferation|activation of activated T cell proliferation|stimulation of activated T cell proliferation|positive regulation of activated T-lymphocyte proliferation|up regulation of activated T cell proliferation													biological_process											owl:Class	
GO:1904398	biolink:NamedThing	positive regulation of neuromuscular junction development	Any process that activates or increases the frequency, rate or extent of neuromuscular junction development.	got7fsn_ti	up-regulation of neuromuscular junction development|positive regulation of neuromuscular junction stability|up regulation of neuromuscular junction development|upregulation of neuromuscular junction stability|positive regulation of NMJ stability|up regulation of neuromuscular junction organization|up regulation of neuromuscular junction stability|activation of neuromuscular junction stability|up-regulation of neuromuscular junction organization|activation of neuromuscular junction organization|up regulation of NMJ stability|activation of NMJ stability|upregulation of neuromuscular junction organization|up-regulation of neuromuscular junction stability|up-regulation of NMJ stability|upregulation of neuromuscular junction development|activation of neuromuscular junction development|upregulation of NMJ stability|positive regulation of neuromuscular junction organization						sl	2015-06-23T19:23:54Z						biological_process											owl:Class	
GO:1900927	biolink:NamedThing	negative regulation of L-threonine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell.	got7fsn_ti	down-regulation of L-threonine import|negative regulation of L-threonine uptake|down-regulation of L-threonine uptake|downregulation of L-threonine uptake|inhibition of L-threonine import|inhibition of L-threonine uptake|down regulation of L-threonine import|downregulation of L-threonine import|down regulation of L-threonine uptake						al	2012-06-13T07:41:52Z						biological_process											owl:Class	
GO:1900295	biolink:NamedThing	negative regulation of heptasaccharide transport	Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport.	got7fsn_ti	down-regulation of heptasaccharide transport|inhibition of heptasaccharide transport|downregulation of heptasaccharide transport|down regulation of heptasaccharide transport						tt	2012-04-05T07:40:49Z						biological_process											owl:Class	
GO:1905436	biolink:NamedThing	negative regulation of histone H3-K4 trimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 trimethylation.	got7fsn_ti	down-regulation of histone H3-K4 trimethylation|inhibition of histone H3-K4 trimethylation|down regulation of histone H3-K4 trimethylation|downregulation of histone H3-K4 trimethylation						hbye	2016-09-14T13:09:03Z						biological_process											owl:Class	
GO:1904604	biolink:NamedThing	negative regulation of advanced glycation end-product receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity.	got7fsn_ti	down regulation of advanced glycation end-product receptor activity|down-regulation of AGE receptor activity|inhibition of advanced glycation end-product receptor activity|down regulation of RAGE activity|downregulation of advanced glycation end-product receptor activity|downregulation of AGE receptor activity|down-regulation of RAGE activity|down-regulation of advanced glycation end-product receptor activity|inhibition of AGE receptor activity|downregulation of RAGE activity|down regulation of AGE receptor activity|inhibition of RAGE activity|negative regulation of RAGE activity|negative regulation of AGE receptor activity						krc	2015-08-26T16:24:56Z						biological_process											owl:Class	
GO:1905253	biolink:NamedThing	obsolete negative regulation of epidermal growth factor receptor signaling pathway involved in heart process	OBSOLETE. Any negative regulation of epidermal growth factor receptor signaling pathway that is involved in heart process.	got7fsn_ti	negative regulation of EGFR signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signaling pathway involved in heart process|down-regulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signalling pathway involved in heart process				This term was obsoleted at the TermGenie Gatekeeper stage.		bc	2016-06-10T09:21:10Z		True				biological_process											owl:Class	
GO:2000154	biolink:NamedThing	obsolete negative regulation of flagellar cell motility	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of flagellar cell motility.	got7fsn_ti	negative regulation of flagellar cell motility				This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:1902020|GO:1902201	mah	2010-10-04T12:41:04Z		True				biological_process											owl:Class	
GO:0033884	biolink:NamedThing	obsolete phosphoethanolamine/phosphocholine phosphatase activity	OBSOLETE. Catalysis of the reactions: O-phosphoethanolamine + H2O = ethanolamine + phosphate, and phosphocholine + H2O = choline + phosphate.	got7fsn_ti	phosphoethanolamine phosphohydrolase activity|phosphoethanolamine/phosphocholine phosphatase activity|3X11A|PHOSPHO1				This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052732|GO:0052731				True				molecular_function											owl:Class	
CHEBI:26523	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001915	biolink:NamedThing	negative regulation of T cell mediated cytotoxicity	Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.	got7fsn_ti	negative regulation of T-cell mediated cell death|negative regulation of T-cell mediated cytolysis|negative regulation of T-cell mediated apoptosis|negative regulation of T-lymphocyte mediated cytotoxicity|negative regulation of T cell mediated cytolysis|down-regulation of T cell mediated cytotoxicity|negative regulation of T cell mediated cell killing|negative regulation of T-cell mediated cytotoxicity|negative regulation of T lymphocyte mediated cytotoxicity|negative regulation of T cell mediated apoptosis|downregulation of T cell mediated cytotoxicity|negative regulation of T cell mediated cell death|inhibition of T cell mediated cytotoxicity|negative regulation of T-cell mediated cell killing|down regulation of T cell mediated cytotoxicity													biological_process											owl:Class	
GO:1903385	biolink:NamedThing	regulation of homophilic cell adhesion	Any process that modulates the frequency, rate or extent of homophilic cell adhesion.	got7fsn_ti							als	2014-08-27T09:57:30Z						biological_process											owl:Class	
GO:0048078	biolink:NamedThing	positive regulation of compound eye pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.	got7fsn_ti	up regulation of eye pigmentation|stimulation of eye pigmentation|activation of eye pigmentation|upregulation of eye pigmentation|positive regulation of eye pigmentation|up-regulation of eye pigmentation													biological_process											owl:Class	
GO:0052402	biolink:NamedThing	obsolete induction by organism of symbiont resistance gene-dependent defense response	OBSOLETE. The activation by an organism of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of defense response in symbiont by specific elicitors|activation by organism of symbiont resistance gene-dependent defense response|activation by organism of defense response in symbiont by specific elicitors|induction by organism of symbiont gene-for-gene resistance|activation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|induction by organism of symbiont resistance gene-dependent defense response|activation by organism of symbiont gene-for-gene resistance|induction by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1902260	biolink:NamedThing	negative regulation of delayed rectifier potassium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity.	got7fsn_ti	down-regulation of delayed rectifier potassium channel activity|inhibition of delayed rectifier potassium channel activity|down regulation of delayed rectifier potassium channel activity|downregulation of delayed rectifier potassium channel activity						rl	2013-06-25T12:16:24Z						biological_process											owl:Class	
GO:1903099	biolink:NamedThing	positive regulation of CENP-A containing nucleosome assembly	Any process that activates or increases the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.	got7fsn_ti	upregulation of CENP-A deposition|upregulation of CenH3-containing nucleosome assembly at centromere|up-regulation of CenH3-containing nucleosome assembly at centromere|up-regulation of centromere specific nucleosome exchange|up-regulation of centromere-specific histone exchange|up regulation of CENP-A loading|up regulation of CENP-A containing nucleosome assembly at centromere|positive regulation of centromere specific nucleosome exchange|activation of CENP-A containing nucleosome assembly at centromere|up regulation of centromere specific nucleosome exchange|positive regulation of DNA replication-independent nucleosome assembly at centromere|up-regulation of centromeric DNA replication-independent nucleosome assembly|upregulation of centromere specific nucleosome exchange|up regulation of CenH3-containing nucleosome assembly at centromere|activation of centromere-specific nucleosome assembly|upregulation of centromeric DNA replication-independent nucleosome assembly|activation of CenH3-containing nucleosome assembly at centromere|upregulation of CENP-A loading|upregulation of centromere-specific histone exchange|activation of centromere-specific histone exchange|upregulation of DNA replication-independent nucleosome assembly at centromere|positive regulation of CENP-A deposition|activation of CENP-A deposition|up regulation of DNA replication-independent nucleosome assembly at centromere|up regulation of centromere-specific histone exchange|up regulation of CENP-A deposition|positive regulation of centromere-specific nucleosome assembly|positive regulation of centromeric DNA replication-independent nucleosome assembly|upregulation of CENP-A containing nucleosome assembly at centromere|activation of centromere specific nucleosome exchange|activation of DNA replication-independent nucleosome assembly at centromere|activation of CENP-A loading|up-regulation of CENP-A deposition|upregulation of centromere-specific nucleosome assembly|up regulation of centromeric DNA replication-independent nucleosome assembly|positive regulation of CENP-A loading|up-regulation of centromere-specific nucleosome assembly|positive regulation of centromere-specific histone exchange|positive regulation of CenH3-containing nucleosome assembly at centromere|activation of centromeric DNA replication-independent nucleosome assembly|up-regulation of DNA replication-independent nucleosome assembly at centromere|up regulation of centromere-specific nucleosome assembly|up-regulation of CENP-A containing nucleosome assembly at centromere|up-regulation of CENP-A loading						vw	2014-06-03T16:15:42Z						biological_process											owl:Class	
GO:0002831	biolink:NamedThing	regulation of response to biotic stimulus	Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.									biological_process											owl:Class	
GO:0032573	biolink:NamedThing	response to phylloquinone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.	got7fsn_ti	response to vitamin K1													biological_process											owl:Class	
GO:1901900	biolink:NamedThing	regulation of protein localization to cell division site	Any process that modulates the frequency, rate or extent of protein localization to cell division site.	got7fsn_ti	regulation of protein localisation to cell division site						dph	2013-02-11T12:27:55Z						biological_process											owl:Class	
GO:1903422	biolink:NamedThing	negative regulation of synaptic vesicle recycling	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling.	got7fsn_ti	downregulation of synaptic vesicle recycling|inhibition of kiss-and-run synaptic vesicle recycling|downregulation of kiss-and-stay synaptic vesicle recycling|negative regulation of kiss-and-stay synaptic vesicle recycling|down regulation of kiss-and-stay synaptic vesicle recycling|down-regulation of synaptic vesicle recycling|downregulation of kiss-and-run synaptic vesicle recycling|negative regulation of kiss-and-run synaptic vesicle recycling|inhibition of kiss-and-stay synaptic vesicle recycling|down-regulation of kiss-and-run synaptic vesicle recycling|inhibition of synaptic vesicle recycling|down regulation of synaptic vesicle recycling|down-regulation of kiss-and-stay synaptic vesicle recycling|down regulation of kiss-and-run synaptic vesicle recycling				An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype		pad	2014-09-09T15:27:59Z						biological_process											owl:Class	
GO:0075082	biolink:NamedThing	obsolete positive regulation by host of symbiont transmembrane receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:1902324	biolink:NamedThing	positive regulation of methyl-branched fatty acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.	got7fsn_ti	up-regulation of methyl-branched fatty acid anabolism|positive regulation of methyl-branched fatty acid anabolism|upregulation of methyl-branched fatty acid formation|upregulation of methyl-branched fatty acid anabolism|up-regulation of methyl-branched fatty acid synthesis|activation of methyl-branched fatty acid anabolism|activation of methyl-branched fatty acid formation|upregulation of methyl-branched fatty acid biosynthesis|up-regulation of methyl-branched fatty acid biosynthetic process|positive regulation of methyl-branched fatty acid formation|up-regulation of methyl-branched fatty acid biosynthesis|activation of methyl-branched fatty acid synthesis|activation of methyl-branched fatty acid biosynthesis|up-regulation of methyl-branched fatty acid formation|positive regulation of methyl-branched fatty acid biosynthesis|up regulation of methyl-branched fatty acid anabolism|up regulation of methyl-branched fatty acid formation|upregulation of methyl-branched fatty acid biosynthetic process|up regulation of methyl-branched fatty acid biosynthesis|upregulation of methyl-branched fatty acid synthesis|up regulation of methyl-branched fatty acid biosynthetic process|up regulation of methyl-branched fatty acid synthesis|activation of methyl-branched fatty acid biosynthetic process|positive regulation of methyl-branched fatty acid synthesis						kmv	2013-07-24T20:15:31Z						biological_process											owl:Class	
GO:0042992	biolink:NamedThing	obsolete negative regulation of transcription factor import into nucleus	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.	got7fsn_ti	negative regulation of transcription factor import into cell nucleus|down regulation of transcription factor import into nucleus|negative regulation of transcription factor transport from cytoplasm to nucleus|negative regulation of transcription factor-nucleus import|inhibition of transcription factor import into nucleus|downregulation of transcription factor import into nucleus|down-regulation of transcription factor import into nucleus				The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0042308				True				biological_process											owl:Class	
GO:0016506	biolink:NamedThing	obsolete apoptosis activator activity	OBSOLETE. The function held by products which directly activate any step in the process of apoptosis.	got7fsn_ti	apoptosis activator activity			GO:0006915	This term was made obsolete because it represents involvement in a biological process.					True				molecular_function											owl:Class	
GO:0000423	biolink:NamedThing	mitophagy	The selective autophagy process in which a mitochondrion is degraded by macroautophagy.	got7fsn_ti	macromitophagy				Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes.									biological_process											owl:Class	
GO:0099020	biolink:NamedThing	perinuclear endoplasmic reticulum lumen	The volume enclosed by the membranes of the perinuclear endoplasmic reticulum.	got7fsn_ti														cellular_component											owl:Class	
GO:0140653	biolink:NamedThing	fumitremorgin C biosynthetic process	The chemical reactions and pathways resulting in the formation of fumitremorgin C.	got7fsn_ti	fumitremorgin C synthesis|fumitremorgin C biosynthesis|fumitremorgin C formation|fumitremorgin C anabolism	https://github.com/geneontology/go-ontology/issues/21494					pg	2021-05-27T08:37:11Z						biological_process											owl:Class	
GO:0019337	biolink:NamedThing	tetrachloroethylene catabolic process	The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines.	got7fsn_ti	tetrachloroethene catabolism|tetrachloroethylene catabolism|tetrachloroethylene degradation|tetrachloroethene catabolic process|tetrachloroethylene breakdown											MetaCyc:PCEDEG-PWY		biological_process											owl:Class	
GO:1901863	biolink:NamedThing	positive regulation of muscle tissue development	Any process that activates or increases the frequency, rate or extent of muscle tissue development.	got7fsn_ti	upregulation of muscle tissue development|up regulation of muscle tissue development|activation of muscle tissue development|up-regulation of muscle tissue development						yaf	2013-02-01T10:30:57Z						biological_process											owl:Class	
GO:1900896	biolink:NamedThing	regulation of heptadecane biosynthetic process	Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process.	got7fsn_ti	regulation of heptadecane formation|regulation of heptadecane biosynthesis|regulation of heptadecane anabolism|regulation of heptadecane synthesis						tt	2012-06-13T03:27:38Z						biological_process											owl:Class	
GO:0075071	biolink:NamedThing	modulation by symbiont of host autophagy	Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	autophagy during symbiotic interaction|modulation by symbiont of host autophagic process|autophagy involved in symbiotic interaction													biological_process											owl:Class	
GO:0015981	biolink:NamedThing	obsolete passive proton transport, down the electrochemical gradient	OBSOLETE. The passive movement of protons from areas of high proton concentration and electrical potential to areas where concentration and electrical potential are low.	got7fsn_ti	passive proton transport, down the electrochemical gradient				This term was made obsolete because it represents a passive process which occurs without the aid of gene products.	GO:1902600				True				biological_process											owl:Class	
GO:1900473	biolink:NamedThing	obsolete negative regulation of phosphatidylcholine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of phosphatidylcholine formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine synthesis by negative regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T08:13:51Z		True				biological_process											owl:Class	
GO:1903109	biolink:NamedThing	positive regulation of mitochondrial transcription	Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion.	got7fsn_ti	activation of mitochondrial transcription|up-regulation of mitochondrial transcription|upregulation of mitochondrial transcription|activation of transcription from mitochondrial promoter|up regulation of transcription from mitochondrial promoter|positive regulation of transcription from mitochondrial promoter|upregulation of transcription from mitochondrial promoter|up-regulation of transcription from mitochondrial promoter|positive regulation of mitochondrial transcription|up regulation of mitochondrial transcription						al	2014-06-09T11:53:20Z						biological_process											owl:Class	
GO:1904500	biolink:NamedThing	obsolete negative regulation of chromatin-mediated maintenance of transcription	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin-mediated maintenance of transcription.	got7fsn_ti	downregulation of chromatin-mediated maintenance of transcription|down regulation of chromatin-mediated maintenance of transcription|inhibition of chromatin-mediated maintenance of transcription|down-regulation of chromatin-mediated maintenance of transcription				This term was obsoleted because it represents a readout.		nc	2015-07-24T09:31:14Z		True				biological_process											owl:Class	
UBERON:0001777	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900121	biolink:NamedThing	negative regulation of receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.	got7fsn_ti	down regulation of receptor binding|downregulation of receptor binding|inhibition of receptor binding|down-regulation of receptor binding|down regulation of receptor-associated protein activity|inhibition of receptor ligand						bf	2012-02-22T11:40:57Z						biological_process											owl:Class	
GO:0035706	biolink:NamedThing	T-helper 1 cell chemotaxis	The directed movement of a T-helper 1 cell in response to an external stimulus.	got7fsn_ti	Th1 cell chemotaxis						bf	2011-03-02T02:36:49Z						biological_process											owl:Class	
GO:1903663	biolink:NamedThing	L-altrarate catabolic process	The chemical reactions and pathways resulting in the breakdown of L-altrarate.	got7fsn_ti	L-altrarate(1-) breakdown|L-altrarate(1-) catabolism|L-altrarate(1-) degradation						jl	2014-11-26T14:34:28Z						biological_process											owl:Class	
GO:1905285	biolink:NamedThing	fibrous ring of heart morphogenesis	The developmental process by which a fibrous ring of heart is generated and organized.	got7fsn_ti	atrioventricular ring morphogenesis|aortic annulus morphogenesis|anulus fibrosus cordis morphogenesis|annulus fibrosus cordis morphogenesis|Lower's ring morphogenesis|anulus fibrosus of heart morphogenesis|coronary tendon morphogenesis						rl	2016-06-21T09:46:54Z						biological_process											owl:Class	
GO:1901455	biolink:NamedThing	negative regulation of response to toluene	Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene.	got7fsn_ti	inhibition of response to toluene|down regulation of response to toluene|down-regulation of response to toluene|downregulation of response to toluene						tt	2012-10-02T14:23:28Z						biological_process											owl:Class	
GO:1903365	biolink:NamedThing	regulation of fear response	Any process that modulates the frequency, rate or extent of fear response.	got7fsn_ti	regulation of physiological fear response						mr	2014-08-21T23:21:36Z						biological_process											owl:Class	
GO:1900846	biolink:NamedThing	regulation of naphtho-gamma-pyrone biosynthetic process	Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.	got7fsn_ti	regulation of naphtho-gamma-pyrones biosynthesis|regulation of naphtho-gamma-pyrone biosynthesis|regulation of naphtho-gamma-pyrones formation|regulation of naphtho-gamma-pyrone formation|regulation of naphtho-gamma-pyrone anabolism|regulation of naphtho-gamma-pyrone synthesis|regulation of naphtho-gamma-pyrones synthesis|regulation of naphtho-gamma-pyrones biosynthetic process|regulation of naphtho-gamma-pyrones anabolism						di	2012-06-07T09:42:41Z						biological_process											owl:Class	
GO:0051496	biolink:NamedThing	positive regulation of stress fiber assembly	Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.	got7fsn_ti	up regulation of stress fiber formation|activation of stress fiber formation|positive regulation of stress fibre formation|positive regulation of stress fibre biosynthesis|upregulation of stress fiber formation|stimulation of stress fiber formation|up-regulation of stress fiber formation													biological_process											owl:Class	
GO:1901600	biolink:NamedThing	strigolactone metabolic process	The chemical reactions and pathways involving strigolactone.	got7fsn_ti	strigolactone metabolism						tb	2012-11-08T01:20:09Z						biological_process											owl:Class	
GO:0002303	biolink:NamedThing	gamma-delta T cell differentiation involved in immune response	The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	got7fsn_ti	gamma-delta T cell development involved in immune response|gamma-delta T cell differentiation during immune response|gamma-delta T-cell differentiation during immune response|gamma-delta T-lymphocyte differentiation during immune response|gamma-delta T lymphocyte differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0009472	biolink:NamedThing	obsolete cytochrome c3 (tetraheme)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytochrome c3 (tetraheme)				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0060635	biolink:NamedThing	positive regulation of (1->3)-beta-D-glucan biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.	got7fsn_ti	positive regulation of 1,3-beta-D-glucan biosynthetic process						dph	2009-05-18T03:22:44Z						biological_process											owl:Class	
GO:0030180	biolink:NamedThing	obsolete solute:solute exchange	OBSOLETE. Exchange diffusion of two solutes between the inside and outside of a cell or subcellular compartment, in which movement of one solute down a concentration gradient drives movement of the other solute in the opposite direction.	got7fsn_ti	solute:solute exchange				This term was made obsolete because it represents a molecular function.	GO:0006810|GO:0015297				True				biological_process											owl:Class	
GO:0009077	biolink:NamedThing	obsolete histidine family amino acid catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of amino acids of the histidine family.	got7fsn_ti	histidine family amino acid catabolic process|histidine family amino acid breakdown|histidine family amino acid degradation|histidine family amino acid catabolism			GO:0006548	This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family.					True				biological_process											owl:Class	
GO:1901759	biolink:NamedThing	beta-L-Ara4N-lipid A metabolic process	The chemical reactions and pathways involving beta-L-Ara4N-lipid A.	got7fsn_ti	4-amino-4-deoxy-beta-L-arabinose-lipid A metabolism|beta-L-Ara4N-lipid A metabolism|4-amino-4-deoxy-beta-L-arabinose-lipid A metabolic process						pr	2013-01-14T12:52:57Z						biological_process											owl:Class	
GO:2001215	biolink:NamedThing	regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	Any process that modulates the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.	got7fsn_ti	regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|regulation of HMG-CoA reductase activity						bf	2011-11-16T11:34:11Z						biological_process											owl:Class	
GO:0098887	biolink:NamedThing	neurotransmitter receptor transport, endosome to postsynaptic membrane	The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.	got7fsn_ti	postsynaptic neurotransmitter receptor endosomal trafficking													biological_process											owl:Class	
GO:0048097	biolink:NamedThing	obsolete long-term maintenance of gene activation	OBSOLETE. Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22015			This term has been obsoleted because its definition was not clear, and had no references and no annotations.	GO:0045815				True				biological_process											owl:Class	
GO:1902729	biolink:NamedThing	negative regulation of proteoglycan biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	got7fsn_ti	inhibition of proteoglycan anabolism|down regulation of proteoglycan synthesis|negative regulation of proteoglycan biosynthesis|negative regulation of proteoglycan synthesis|inhibition of proteoglycan biosynthesis|down regulation of proteoglycan formation|down-regulation of proteoglycan synthesis|down-regulation of proteoglycan formation|down regulation of proteoglycan biosynthesis|down-regulation of proteoglycan anabolism|downregulation of proteoglycan synthesis|down-regulation of proteoglycan biosynthesis|inhibition of proteoglycan biosynthetic process|downregulation of proteoglycan anabolism|down-regulation of proteoglycan biosynthetic process|inhibition of proteoglycan formation|down regulation of proteoglycan anabolism|down regulation of proteoglycan biosynthetic process|inhibition of proteoglycan synthesis|downregulation of proteoglycan biosynthetic process|downregulation of proteoglycan formation|negative regulation of proteoglycan anabolism|downregulation of proteoglycan biosynthesis|negative regulation of proteoglycan formation						mr	2014-02-24T16:10:43Z						biological_process											owl:Class	
GO:0017030	biolink:NamedThing	obsolete beta-galactosidase stabilization activity	OBSOLETE. Stabilization of the structure of beta-galactosidase.	got7fsn_ti	beta-galactosidase stabilization activity			GO:0050821	This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:0051057	biolink:NamedThing	positive regulation of small GTPase mediated signal transduction	Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.	got7fsn_ti	upregulation of small GTPase mediated signal transduction|stimulation of small GTPase mediated signal transduction|up-regulation of small GTPase mediated signal transduction|positive regulation of small GTPase-mediated signal transduction|activation of small GTPase mediated signal transduction|up regulation of small GTPase mediated signal transduction													biological_process											owl:Class	
GO:1903951	biolink:NamedThing	positive regulation of AV node cell action potential	Any process that activates or increases the frequency, rate or extent of AV node cell action potential.	got7fsn_ti	up regulation of atrioventricular node cardiac muscle cell action potential|activation of AV node cardiac muscle cell action potential|upregulation of AV node cell action potential|up regulation of AV node cardiac muscle cell action potential|positive regulation of atrioventricular node cardiac muscle cell action potential|positive regulation of AV node cardiac muscle cell action potential|upregulation of atrioventricular node cardiac muscle cell action potential|up-regulation of AV node cardiac muscle cell action potential|activation of AV node cell action potential|activation of atrioventricular node cardiac muscle cell action potential|up-regulation of AV node cell action potential|up-regulation of atrioventricular node cardiac muscle cell action potential|up regulation of AV node cell action potential|upregulation of AV node cardiac muscle cell action potential						nc	2015-02-20T14:59:50Z						biological_process											owl:Class	
GO:0086103	biolink:NamedThing	G protein-coupled receptor signaling pathway involved in heart process	An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart.	got7fsn_ti	GPCR signaling pathway involved in cardiac process|GPCR signaling pathway involved in heart process|G-protein coupled receptor signalling pathway involved in heart process|G-protein coupled receptor signaling pathway involved in heart process						bf	2012-03-19T01:28:23Z						biological_process											owl:Class	
GO:0030861	biolink:NamedThing	negative regulation of polarized epithelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation.	got7fsn_ti	downregulation of polarized epithelial cell differentiation|down-regulation of polarized epithelial cell differentiation|down regulation of polarized epithelial cell differentiation|inhibition of polarized epithelial cell differentiation													biological_process											owl:Class	
GO:0061938	biolink:NamedThing	protein localization to somatodendritic compartment	A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.	got7fsn_ti	somatodendritic protein localization						dph	2017-09-08T13:22:26Z						biological_process											owl:Class	
GO:1903568	biolink:NamedThing	negative regulation of protein localization to ciliary membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane.	got7fsn_ti	down-regulation of protein localisation to ciliary membrane|downregulation of protein localisation to ciliary membrane|downregulation of protein localization in ciliary membrane|inhibition of protein localisation in ciliary membrane|inhibition of protein localization to ciliary membrane|down-regulation of protein localisation in ciliary membrane|downregulation of protein localisation in ciliary membrane|down-regulation of protein localization to ciliary membrane|down regulation of protein localization in ciliary membrane|down-regulation of protein localization in ciliary membrane|downregulation of protein localization to ciliary membrane|down regulation of protein localisation in ciliary membrane|negative regulation of protein localisation to ciliary membrane|negative regulation of protein localisation in ciliary membrane|inhibition of protein localisation to ciliary membrane|inhibition of protein localization in ciliary membrane|down regulation of protein localisation to ciliary membrane|negative regulation of protein localization in ciliary membrane|down regulation of protein localization to ciliary membrane						krc	2014-10-24T21:32:59Z						biological_process											owl:Class	
GO:0051280	biolink:NamedThing	negative regulation of release of sequestered calcium ion into cytosol	Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.	got7fsn_ti	negative regulation of calcium ion (Ca2+) mobilization|inhibition of release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion into cytoplasm|negative regulation of release of stored calcium ion (Ca2+)|negative regulation of cytoplasmic release of stored calcium ion (Ca2+)|down regulation of release of sequestered calcium ion into cytosol|negative regulation of release of stored calcium ion (Ca2+) into cytoplasm|negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|down-regulation of release of sequestered calcium ion into cytosol|negative regulation of cytosolic release of sequestered calcium ion (Ca2+)|negative regulation of release of stored calcium ion (Ca2+) into cytosol|negative regulation of release of sequestered calcium ion (Ca2+)|negative regulation of cytosolic release of stored calcium ion (Ca2+)|negative regulation of calcium mobilization|downregulation of release of sequestered calcium ion into cytosol													biological_process											owl:Class	
GO:0030463	biolink:NamedThing	obsolete cell aging (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cell aging (sensu Fungi)			GO:0007569	This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'.					True				biological_process											owl:Class	
GO:0061866	biolink:NamedThing	negative regulation of histone H3-S10 phosphorylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to histone H3 on a serine residue at position 10.	got7fsn_ti							dph	2017-04-07T18:45:51Z						biological_process											owl:Class	
GO:0015264	biolink:NamedThing	methylammonium channel activity	Enables the facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2.	got7fsn_ti														molecular_function											owl:Class	
GO:1900210	biolink:NamedThing	positive regulation of cardiolipin metabolic process	Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.	got7fsn_ti	positive regulation of diphosphatidylglycerol metabolism|up-regulation of cardiolipin metabolic process|up-regulation of cardiolipin metabolism|positive regulation of diphosphatidylglycerol metabolic process|positive regulation of cardiolipin metabolism|upregulation of diphosphatidylglycerol metabolic process|upregulation of cardiolipin metabolic process|up-regulation of diphosphatidylglycerol metabolic process|up regulation of cardiolipin metabolic process|up regulation of diphosphatidylglycerol metabolism|activation of cardiolipin metabolic process|activation of diphosphatidylglycerol metabolic process|upregulation of diphosphatidylglycerol metabolism|activation of diphosphatidylglycerol metabolism|up regulation of diphosphatidylglycerol metabolic process|up regulation of cardiolipin metabolism|activation of cardiolipin metabolism|upregulation of cardiolipin metabolism|up-regulation of diphosphatidylglycerol metabolism						jl	2012-03-22T10:43:51Z						biological_process											owl:Class	
GO:1902018	biolink:NamedThing	negative regulation of cilium assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.	got7fsn_ti	negative regulation of cilium biogenesis|down-regulation of cilium assembly|down regulation of cilium assembly|down regulation of cilium biogenesis|inhibition of ciliogenesis|downregulation of ciliogenesis|inhibition of cilium biogenesis|downregulation of cilium assembly|down-regulation of cilium biogenesis|inhibition of cilium assembly|down regulation of ciliogenesis|downregulation of cilium biogenesis|down-regulation of ciliogenesis|negative regulation of ciliogenesis						dph	2013-03-26T18:10:56Z						biological_process											owl:Class	
GO:1903883	biolink:NamedThing	positive regulation of interleukin-17-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway.	got7fsn_ti	up-regulation of interleukin-17-mediated signalling pathway|positive regulation of IL-17-mediated signaling pathway|upregulation of interleukin-17-mediated signaling pathway|up regulation of IL-17-mediated signaling pathway|up-regulation of IL-17-mediated signalling pathway|activation of IL-17-mediated signaling pathway|positive regulation of interleukin-17-mediated signalling pathway|upregulation of interleukin-17-mediated signalling pathway|upregulation of IL-17-mediated signaling pathway|up regulation of interleukin-17-mediated signalling pathway|activation of interleukin-17-mediated signalling pathway|upregulation of IL-17-mediated signalling pathway|up regulation of IL-17-mediated signalling pathway|activation of interleukin-17-mediated signaling pathway|up regulation of interleukin-17-mediated signaling pathway|up-regulation of IL-17-mediated signaling pathway|positive regulation of IL-17-mediated signalling pathway|activation of IL-17-mediated signalling pathway|up-regulation of interleukin-17-mediated signaling pathway						krc	2015-02-06T16:26:56Z						biological_process											owl:Class	
GO:0072436	biolink:NamedThing	obsolete detection of stimulus involved in DNA replication checkpoint	OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a DNA replication checkpoint.	got7fsn_ti	sensing involved in DNA replication checkpoint|DNA replication checkpoint sensor process|DNA replication checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:52:09Z		True				biological_process											owl:Class	
GO:1903334	biolink:NamedThing	positive regulation of protein folding	Any process that activates or increases the frequency, rate or extent of protein folding.	got7fsn_ti	up-regulation of protein complex assembly, multichaperone pathway|upregulation of co-chaperone activity|up regulation of beta-tubulin folding|up regulation of chaperonin-mediated tubulin folding|positive regulation of alpha-tubulin folding|up regulation of glycoprotein-specific chaperone activity|upregulation of chaperonin-mediated tubulin folding|upregulation of beta-tubulin folding|up regulation of non-chaperonin molecular chaperone ATPase activity|positive regulation of glycoprotein-specific chaperone activity|upregulation of co-chaperonin activity|up-regulation of beta-tubulin folding|upregulation of glycoprotein-specific chaperone activity|up-regulation of chaperonin-mediated tubulin folding|up-regulation of co-chaperonin activity|up regulation of alpha-tubulin folding|upregulation of chaperone activity|up-regulation of chaperonin ATPase activity|activation of chaperone activity|upregulation of non-chaperonin molecular chaperone ATPase activity|positive regulation of chaperonin ATPase activity|activation of alpha-tubulin folding|positive regulation of co-chaperone activity|activation of chaperonin ATPase activity|up regulation of chaperone activity|up-regulation of chaperone activity|up-regulation of co-chaperone activity|upregulation of alpha-tubulin folding|activation of chaperonin-mediated tubulin folding|up regulation of co-chaperone activity|up-regulation of glycoprotein-specific chaperone activity|upregulation of protein folding|positive regulation of protein complex assembly, multichaperone pathway|positive regulation of chaperonin-mediated tubulin folding|activation of protein folding|upregulation of protein complex assembly, multichaperone pathway|up-regulation of protein folding|up-regulation of non-chaperonin molecular chaperone ATPase activity|up regulation of chaperonin ATPase activity|positive regulation of chaperone activity|positive regulation of non-chaperonin molecular chaperone ATPase activity|activation of non-chaperonin molecular chaperone ATPase activity|upregulation of chaperonin ATPase activity|activation of protein complex assembly, multichaperone pathway|activation of beta-tubulin folding|up regulation of protein folding|up regulation of co-chaperonin activity|activation of glycoprotein-specific chaperone activity|up-regulation of alpha-tubulin folding|activation of co-chaperone activity|up regulation of protein complex assembly, multichaperone pathway|positive regulation of beta-tubulin folding|activation of co-chaperonin activity|positive regulation of co-chaperonin activity						vw	2014-08-18T13:14:50Z						biological_process											owl:Class	
GO:0014724	biolink:NamedThing	regulation of twitch skeletal muscle contraction	Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:1901151	biolink:NamedThing	vistamycin catabolic process	The chemical reactions and pathways resulting in the breakdown of vistamycin.	got7fsn_ti	ribostamycin breakdown|ribostamycin catabolism|vistamycin degradation|vistamycin breakdown|vistamycin catabolism|ribostamycin degradation|ribostamycin catabolic process						yaf	2012-07-17T04:27:07Z						biological_process											owl:Class	
GO:0046751	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903399	biolink:NamedThing	positive regulation of m7G(5')pppN diphosphatase activity	Any process that activates or increases the frequency, rate or extent of m7G(5')pppN diphosphatase activity.	got7fsn_ti	upregulation of m7G(5')pppN diphosphatase activity|positive regulation of m7G(5')pppN pyrophosphatase activity|upregulation of decapase activity|up-regulation of M(7)G(5')pppN pyrophosphatase activity|activation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up-regulation of m7G(5')pppN diphosphatase activity|upregulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|positive regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up-regulation of m7G(5')pppN pyrophosphatase activity|activation of decapase activity|positive regulation of decapase activity|up-regulation of decapase activity|up regulation of M(7)G(5')pppN pyrophosphatase activity|activation of m7G(5')pppN diphosphatase activity|upregulation of M(7)G(5')pppN pyrophosphatase activity|activation of m7G(5')pppN pyrophosphatase activity|up regulation of m7G(5')pppN diphosphatase activity|positive regulation of M(7)G(5')pppN pyrophosphatase activity|up regulation of decapase activity|up-regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|activation of M(7)G(5')pppN pyrophosphatase activity|up regulation of m7G(5')pppN pyrophosphatase activity|upregulation of m7G(5')pppN pyrophosphatase activity						mah	2014-09-01T10:16:49Z						biological_process											owl:Class	
GO:0071616	biolink:NamedThing	acyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.	got7fsn_ti	acyl-CoA anabolism|acyl-CoA synthesis|acyl-CoA biosynthesis|acyl-CoA formation						mah	2010-02-08T04:43:31Z						biological_process											owl:Class	
GO:1905660	biolink:NamedThing	mitotic checkpoint complex assembly	The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex.	got7fsn_ti	mitotic checkpoint complex formation|MCC assembly|MCC formation						mah	2016-11-09T14:17:41Z						biological_process											owl:Class	
GO:0031303	biolink:NamedThing	integral component of endosome membrane	The component of the endosome membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to endosome membrane													cellular_component											owl:Class	
GO:1900638	biolink:NamedThing	negative regulation of asperfuranone biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process.	got7fsn_ti	down-regulation of asperfuranone biosynthesis|inhibition of asperfuranone biosynthetic process|negative regulation of asperfuranone anabolism|down regulation of asperfuranone synthesis|down regulation of asperfuranone biosynthetic process|inhibition of asperfuranone synthesis|downregulation of asperfuranone biosynthetic process|negative regulation of asperfuranone synthesis|downregulation of asperfuranone formation|down-regulation of asperfuranone biosynthetic process|down-regulation of asperfuranone synthesis|inhibition of asperfuranone biosynthesis|downregulation of asperfuranone biosynthesis|inhibition of asperfuranone anabolism|down-regulation of asperfuranone anabolism|downregulation of asperfuranone anabolism|down regulation of asperfuranone anabolism|negative regulation of asperfuranone biosynthesis|inhibition of asperfuranone formation|downregulation of asperfuranone synthesis|down regulation of asperfuranone biosynthesis|negative regulation of asperfuranone formation|down-regulation of asperfuranone formation|down regulation of asperfuranone formation						di	2012-05-22T03:50:16Z						biological_process											owl:Class	
GO:1903895	biolink:NamedThing	negative regulation of IRE1-mediated unfolded protein response	Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.	got7fsn_ti	down regulation of IRE1 signaling in response to endoplasmic reticulum stress|down-regulation of IRE1 signaling in response to endoplasmic reticulum stress|negative regulation of IRE1alpha unfolded protein response|negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|negative regulation of UPR signaling by IRE1 stress sensor|inhibition of IRE1 branch of UPR|down-regulation of IRE1p unfolded protein response|down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction|down-regulation of UPR signaling by IRE1 stress sensor|downregulation of UPR signaling by IRE1 stress sensor|downregulation of IRE1 signaling in response to endoplasmic reticulum stress|down regulation of IRE1p unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|downregulation of IRE1p unfolded protein response|downregulation of IRE1-mediated unfolded protein response|negative regulation of ERN1-mediated unfolded protein response|down-regulation of IRE1 branch of UPR|down-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down-regulation of IRE1alpha unfolded protein response|downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|inhibition of UPR signaling by IRE1 stress sensor|down-regulation of IRE1-mediated unfolded protein response|inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling|inhibition of IRE1alpha unfolded protein response|negative regulation of IRE1 signaling in response to endoplasmic reticulum stress|negative regulation of IRE1p unfolded protein response|down-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|down regulation of UPR signaling by IRE1 stress sensor|down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|negative regulation of IRE1 branch of UPR|inhibition of IRE1 signaling in response to endoplasmic reticulum stress|downregulation of IRE1 branch of UPR|down regulation of IRE1alpha unfolded protein response|down regulation of IRE1 branch of UPR|down regulation of IRE1-mediated unfolded protein response|downregulation of IRE1alpha unfolded protein response|inhibition of IRE1-mediated unfolded protein response|inhibition of IRE1p unfolded protein response						bf	2015-02-09T10:17:55Z						biological_process											owl:Class	
GO:1900043	biolink:NamedThing	obsolete leptin-mediated signaling pathway involved in negative regulation of appetite	OBSOLETE. Any leptin-mediated signaling pathway that is involved in negative regulation of appetite.	got7fsn_ti	leptin-mediated signaling pathway of appetite suppression|leptin-mediated signaling pathway of down-regulation of appetite|adipocytokine signaling pathway of negative regulation of hunger|leptin-mediated signaling pathway of negative regulation of hunger|adipocytokine signaling pathway of down-regulation of appetite|leptin-mediated signaling pathway of down regulation of appetite|leptin-mediated signaling pathway of downregulation of appetite|leptin-mediated signalling pathway of negative regulation of appetite|leptin-mediated signaling pathway involved in negative regulation of appetite|adipocytokine signaling pathway of down regulation of appetite|leptin-mediated signalling pathway of down regulation of appetite|leptin-mediated signalling pathway of negative regulation of hunger|leptin-mediated signaling pathway of negative regulation of appetite|adipocytokine signaling pathway of negative regulation of appetite|adipocytokine signaling pathway of downregulation of appetite|leptin-mediated signalling pathway of down-regulation of appetite|adipocytokine signaling pathway of inhibition of appetite|leptin-mediated signalling pathway of inhibition of appetite|leptin-mediated signalling pathway of downregulation of appetite|leptin-mediated signalling pathway of appetite suppression|leptin-mediated signaling pathway of inhibition of appetite|adipocytokine signaling pathway of appetite suppression				This term was obsoleted at the TermGenie Gatekeeper stage.		vk	2012-01-19T11:10:22Z		True				biological_process											owl:Class	
GO:1905359	biolink:NamedThing	protein localization to meiotic spindle	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle.	got7fsn_ti	protein localisation to meiotic spindle						mah	2016-08-10T14:49:03Z						biological_process											owl:Class	
GO:0002636	biolink:NamedThing	positive regulation of germinal center formation	Any process that activates or increases the frequency, rate, or extent of germinal center formation.	got7fsn_ti	upregulation of germinal center formation|activation of germinal center formation|up-regulation of germinal center formation|up regulation of germinal center formation|stimulation of germinal center formation													biological_process											owl:Class	
GO:1905503	biolink:NamedThing	regulation of motile cilium assembly	Any process that modulates the frequency, rate or extent of motile cilium assembly.	got7fsn_ti	regulation of motile primary cilium assembly|regulation of nodal cilium formation|regulation of motile primary cilia assembly|regulation of nodal cilium assembly|regulation of motile primary cilium formation|regulation of motile primary cilia formation						krc	2016-09-27T18:27:47Z						biological_process											owl:Class	
GO:1900905	biolink:NamedThing	regulation of hexadecanal metabolic process	Any process that modulates the frequency, rate or extent of hexadecanal metabolic process.	got7fsn_ti	regulation of hexadecanal metabolism						tt	2012-06-13T03:35:27Z						biological_process											owl:Class	
GO:1904721	biolink:NamedThing	obsolete negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.	got7fsn_ti	inhibition of HAC1 mRNA cleavage|down regulation of HAC1-type intron splice site recognition and cleavage|down-regulation of HAC1-type intron splice site recognition and cleavage|negative regulation of HAC1 mRNA cleavage|inhibition of IRE1-mediated XBP-1 mRNA cleavage|down-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|inhibition of HAC1-type intron splice site recognition and cleavage|down regulation of XBP1 mRNA cleavage|down regulation of HAC1 mRNA cleavage|negative regulation of IRE1-mediated XBP-1 mRNA cleavage|downregulation of mRNA endonucleolytic cleavage involved in unfolded protein response|negative regulation of XBP1 mRNA cleavage|inhibition of mRNA endonucleolytic cleavage involved in unfolded protein response|downregulation of HAC1 mRNA cleavage|downregulation of IRE1-mediated XBP-1 mRNA cleavage|down-regulation of IRE1-mediated XBP-1 mRNA cleavage|down regulation of IRE1-mediated XBP-1 mRNA cleavage|down regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|negative regulation of HAC1-type intron splice site recognition and cleavage|inhibition of XBP1 mRNA cleavage|down-regulation of XBP1 mRNA cleavage|downregulation of XBP1 mRNA cleavage|down-regulation of HAC1 mRNA cleavage|downregulation of HAC1-type intron splice site recognition and cleavage				The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted.	GO:1903895	bf	2015-10-08T14:52:55Z		True				biological_process											owl:Class	
GO:0032322	biolink:NamedThing	ubiquinone catabolic process	The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme.	got7fsn_ti	ubiquinone breakdown|ubiquinone catabolism|ubiquinone degradation													biological_process											owl:Class	
GO:0045339	biolink:NamedThing	farnesyl diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.	got7fsn_ti	farnesyl diphosphate degradation|farnesyl diphosphate catabolism|farnesyl diphosphate breakdown													biological_process											owl:Class	
GO:0010901	biolink:NamedThing	regulation of very-low-density lipoprotein particle remodeling	Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.	got7fsn_ti	regulation of VLDL remodeling													biological_process											owl:Class	
GO:1902076	biolink:NamedThing	regulation of lateral motor column neuron migration	Any process that modulates the frequency, rate or extent of lateral motor column neuron migration.	got7fsn_ti							pr	2013-04-23T14:42:18Z						biological_process											owl:Class	
GO:0052392	biolink:NamedThing	obsolete induction by organism of defense-related symbiont calcium ion flux	OBSOLETE. The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of symbiont calcium ion flux|activation by organism of symbiont Ca2+ flux|induction by organism of defense-related symbiont calcium ion flux|induction by organism of symbiont Ca2+ flux				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1902170	biolink:NamedThing	cellular response to reactive nitrogen species	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus.	got7fsn_ti							tb	2013-05-23T00:23:59Z			GO:1990106			biological_process											owl:Class	
GO:1904458	biolink:NamedThing	regulation of substance P secretion	Any process that modulates the frequency, rate or extent of substance P secretion.	got7fsn_ti							sl	2015-07-09T19:32:50Z						biological_process											owl:Class	
GO:0044668	biolink:NamedThing	sodium:malonate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).	got7fsn_ti							jl	2012-08-08T11:59:48Z				RHEA:33135		molecular_function											owl:Class	
GO:0018884	biolink:NamedThing	carbazole metabolic process	The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.	got7fsn_ti	CAR metabolism|carbazole metabolism|CAR metabolic process											UM-BBD_pathwayID:car		biological_process											owl:Class	
GO:0042642	biolink:NamedThing	actomyosin, myosin complex part	The myosin part of any complex of actin, myosin, and accessory proteins.	got7fsn_ti														cellular_component											owl:Class	
CL:0012000	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046132	biolink:NamedThing	pyrimidine ribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	pyrimidine ribonucleoside formation|pyrimidine ribonucleoside biosynthesis|pyrimidine ribonucleoside synthesis|pyrimidine ribonucleoside anabolism													biological_process											owl:Class	
GO:0046435	biolink:NamedThing	3-(3-hydroxy)phenylpropionate metabolic process	The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.	got7fsn_ti	3-(3-hydroxy)phenylpropionate metabolism													biological_process											owl:Class	
GO:0000208	biolink:NamedThing	obsolete MAPK import into nucleus involved in osmosensory signaling pathway	OBSOLETE. The directed movement of a MAP kinase to the nucleus during osmolarity sensing.	got7fsn_ti	MAPK import into nucleus during osmolarity sensing|nuclear translocation of MAPK during osmolarity sensing|osmolarity sensing, nuclear translocation of MAPK|nuclear translocation of MAPK involved in osmosensory signalling pathway|MAPK import into nucleus involved in osmosensory signalling pathway|osmolarity sensing, MAPK import into nucleus|nuclear translocation of MAPK involved in osmosensory signaling pathway				The reason for obsoletion is that this term represents a GO-CAM model.	GO:0006606				True				biological_process											owl:Class	
GO:0060545	biolink:NamedThing	positive regulation of necroptotic process	Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.	got7fsn_ti	positive regulation of necroptosis						dph	2009-04-13T01:47:27Z						biological_process											owl:Class	
GO:1900200	biolink:NamedThing	mesenchymal cell apoptotic process involved in metanephros development	Any mesenchymal cell apoptotic process that is involved in metanephros development.	got7fsn_ti	mesenchymal cell apoptosis involved in metanephros development						yaf	2012-03-21T11:58:05Z						biological_process											owl:Class	
GO:2000355	biolink:NamedThing	negative regulation of ovarian follicle development	Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.	got7fsn_ti	negative regulation of follicular phase						yaf	2011-02-03T02:01:32Z						biological_process											owl:Class	
GO:0036040	biolink:NamedThing	curcumin catabolic process	The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin.	got7fsn_ti	(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione degradation|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolism|curcumin breakdown|curcumin degradation|curcumin catabolism|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolic process|turmeric yellow catabolic process|diferuloylmethane catabolic process|diferuloylmethane catabolism|turmeric yellow degradation|diferuloylmethane breakdown|diferuloylmethane degradation|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione breakdown|turmeric yellow catabolism|turmeric yellow breakdown						bf	2011-11-22T02:01:05Z						biological_process											owl:Class	
GO:2000496	biolink:NamedThing	negative regulation of cell proliferation involved in compound eye morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.	got7fsn_ti							bf	2011-03-18T02:19:22Z						biological_process											owl:Class	
GO:1903572	biolink:NamedThing	positive regulation of protein kinase D signaling	Any process that activates or increases the frequency, rate or extent of protein kinase D signaling.	got7fsn_ti	positive regulation of protein kinase D signal transduction|activation of protein kinase D signalling cascade|up-regulation of PKD signal transduction|activation of protein kinase D signaling|activation of PKD signal transduction|up-regulation of PKD signaling cascade|up regulation of protein kinase D signal transduction|activation of protein kinase D signal transduction|positive regulation of PKD signal transduction|upregulation of PKD signal transduction|up-regulation of protein kinase D signaling|up-regulation of protein kinase D signal transduction|upregulation of protein kinase D signalling cascade|activation of protein kinase D signaling cascade|up regulation of PKD signaling cascade|up regulation of protein kinase D signalling cascade|positive regulation of PKD signaling cascade|up regulation of protein kinase D signaling|upregulation of protein kinase D signal transduction|upregulation of protein kinase D signaling cascade|up regulation of protein kinase D signaling cascade|positive regulation of protein kinase D signaling cascade|upregulation of PKD signaling cascade|upregulation of protein kinase D signaling|positive regulation of protein kinase D signalling cascade|up-regulation of protein kinase D signaling cascade|up regulation of PKD signal transduction|activation of PKD signaling cascade|up-regulation of protein kinase D signalling cascade						rl	2014-10-27T15:18:18Z						biological_process											owl:Class	
GO:1905855	biolink:NamedThing	positive regulation of heparan sulfate binding	Any process that activates or increases the frequency, rate or extent of heparan sulfate binding.	got7fsn_ti	up regulation of heparan sulfate binding|activation of heparan sulfate binding|upregulation of heparan sulfate binding|up-regulation of heparan sulfate binding						bc	2017-01-23T13:25:47Z						biological_process											owl:Class	
GO:1905401	biolink:NamedThing	positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process	Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.	got7fsn_ti	up-regulation of activated CD4-positive, alpha-beta T cell apoptotic process|up-regulation of activated CD4-positive, alpha-beta T cell apoptosis|activation of activated CD4-positive, alpha-beta T cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T-cell apoptosis|upregulation of activated CD4-positive, alpha-beta T cell apoptosis|activation of activated CD4-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|positive regulation of activated CD4-positive, alpha-beta T-cell apoptosis|activation of activated CD4-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|up regulation of activated CD4-positive, alpha-beta T cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|upregulation of activated CD4-positive, alpha-beta T-cell apoptosis|upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD4-positive, alpha-beta T cell apoptosis|up regulation of activated CD4-positive, alpha-beta T-cell apoptosis|upregulation of activated CD4-positive, alpha-beta T-cell apoptotic process|activation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T cell apoptotic process|up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process						pga	2016-08-25T09:10:00Z						biological_process											owl:Class	
GO:1905382	biolink:NamedThing	positive regulation of snRNA transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.	got7fsn_ti	upregulation of snRNA transcription from Pol II promoter|up regulation of snRNA transcription from Pol II promoter|activation of snRNA transcription from RNA polymerase II promoter|up regulation of snRNA transcription from RNA polymerase II promoter|positive regulation of snRNA transcription from RNA polymerase II promoter|up-regulation of snRNA transcription from RNA polymerase II promoter|positive regulation of snRNA transcription from Pol II promoter|up-regulation of snRNA transcription from Pol II promoter|upregulation of snRNA transcription from RNA polymerase II promoter|activation of snRNA transcription from Pol II promoter				An example of this is GTF2A1 in human (UniProt symbol P52655) in PMID:10022900 (inferred from direct assay).		bhm	2016-08-18T13:39:34Z						biological_process											owl:Class	
GO:0009678	biolink:NamedThing	pyrophosphate hydrolysis-driven proton transmembrane transporter activity	Enables the transmembrane transport of one proton (H+), driven by the hydrolysis of pyrophosphate, and generating a proton motive force.	got7fsn_ti	proton-translocating pyrophosphatase activity|PP(i) hydrolysis-driven proton transmembrane transporter activity|diphosphate hydrolysis-driven proton transmembrane transporter activity|hydrogen-translocating pyrophosphatase activity|proton-pumping pyrophosphatase|proton-pumping diphosphatase|H(+)-exporting diphosphatase											RHEA:13973|EC:7.1.3.1|TC:3.A.10|MetaCyc:TRANS-RXN-370		molecular_function											owl:Class	
GO:0052506	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|upregulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|induction by organism of defense-related symbiont ethylene-mediated signal transduction pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1900429	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms.	got7fsn_ti	downregulation of filamentous growth of a population of unicellular organisms|down regulation of filamentous growth of a population of unicellular organisms|down-regulation of filamentous growth of a population of unicellular organisms|inhibition of filamentous growth of a population of unicellular organisms						di	2012-04-25T05:53:43Z						biological_process											owl:Class	
GO:0062087	biolink:NamedThing	positive regulation of vein smooth muscle contraction	Any process that increases the frequency, rate or extent of vein smooth muscle contraction.	got7fsn_ti							dph	2018-11-02T15:20:47Z						biological_process											owl:Class	
GO:1905641	biolink:NamedThing	cellular response to acetaldehyde	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.	got7fsn_ti							mah	2016-11-04T15:07:26Z						biological_process											owl:Class	
GO:2000596	biolink:NamedThing	negative regulation of optic nerve formation	Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.	got7fsn_ti	negative regulation of CN II formation|negative regulation of CN II biosynthesis						yaf	2011-04-11T03:41:35Z						biological_process											owl:Class	
GO:0010702	biolink:NamedThing	obsolete regulation of histolysis	OBSOLETE. Any process that modulates the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.	got7fsn_ti					This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0008219|GO:0012501				True				biological_process											owl:Class	
GO:1900403	biolink:NamedThing	obsolete negative regulation of cellular amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cellular amino acid biosynthetic process.	got7fsn_ti	negative regulation of amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid synthesis by negative regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T02:45:42Z		True				biological_process											owl:Class	
GO:0000055	biolink:NamedThing	ribosomal large subunit export from nucleus	The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.	got7fsn_ti	ribosomal large subunit-nucleus export|60S ribosomal subunit export from nucleus|50S ribosomal subunit export from nucleus|ribosomal large subunit transport from nucleus to cytoplasm|ribosomal large subunit export out of nucleus|ribosomal large subunit export from cell nucleus										GO:0000057			biological_process											owl:Class	
GO:1905074	biolink:NamedThing	negative regulation of tight junction disassembly	Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly.	got7fsn_ti	inhibition of occluding cell junction disassembly|downregulation of occluding junction disassembly|down-regulation of tight junction disassembly|negative regulation of tight junction disassembly|inhibition of occluding junction disassembly|inhibition of tight junction disassembly|downregulation of tight junction disassembly|down regulation of tight junction disassembly|negative regulation of occluding cell junction disassembly|down-regulation of occluding cell junction disassembly|down regulation of occluding cell junction disassembly|downregulation of occluding cell junction disassembly						rl	2016-03-23T19:33:01Z						biological_process											owl:Class	
GO:0099616	biolink:NamedThing	extrinsic component of matrix side of mitochondrial inner membrane	The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0150190	biolink:NamedThing	negative regulation of interleukin-32 production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production.	got7fsn_ti	negative regulation of interleukin-32 secretion|negative regulation of interleukin-32 biosynthetic process						bc	2020-02-21T10:31:53Z			GO:0150193			biological_process											owl:Class	
GO:0046277	biolink:NamedThing	methylgallate biosynthetic process	The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.	got7fsn_ti	methylgallate formation|methylgallate synthesis|methylgallate anabolism|methylgallate biosynthesis													biological_process											owl:Class	
GO:0014861	biolink:NamedThing	regulation of skeletal muscle contraction via regulation of action potential	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes.	got7fsn_ti	regulation of skeletal muscle contraction via membrane action potential													biological_process											owl:Class	
GO:1990607	biolink:NamedThing	obsolete detection of stimulus involved in cytokinesis after mitosis checkpoint	OBSOLETE. The series of events in which information about whether cytokinesis has correctly completed, is received and converted into a molecular signal, contributing to a cytokinesis after mitosis checkpoint.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		jl	2015-01-19T14:43:34Z		True				biological_process											owl:Class	
GO:2000915	biolink:NamedThing	regulation of glucuronoxylan catabolic process	Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process.	got7fsn_ti	regulation of glucuronoxylan catabolism						tt	2011-07-29T07:54:35Z						biological_process											owl:Class	
GO:2000095	biolink:NamedThing	regulation of Wnt signaling pathway, planar cell polarity pathway	Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.	got7fsn_ti	regulation of PCP pathway|regulation of Wnt-activated signaling pathway, planar cell polarity pathway|regulation of non-canonical Wnt signaling pathway|regulation of Wnt receptor signaling pathway, planar cell polarity pathway|regulation of Wnt-PCP signaling pathway|regulation of Wnt-JNK signaling pathway|regulation of Wnt receptor signalling pathway, planar cell polarity pathway						jl	2010-09-08T01:07:39Z						biological_process											owl:Class	
GO:2000721	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	Any positive regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.	got7fsn_ti	activation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|activation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter, global of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|upregulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|stimulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|stimulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of transcription from Pol II promoter of smooth muscle cell differentiation|activation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up-regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol II promoter of nonstriated muscle cell differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|stimulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up-regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|activation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of global transcription from Pol II promoter of nonstriated muscle cell differentiation|upregulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter, global of smooth muscle cell differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter of smooth muscle cell differentiation|stimulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of global transcription from Pol II promoter of smooth muscle cell differentiation|up-regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up-regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation						vk	2011-06-08T08:34:55Z						biological_process											owl:Class	
GO:0010520	biolink:NamedThing	regulation of reciprocal meiotic recombination	Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti														biological_process											owl:Class	
GO:0005194	biolink:NamedThing	obsolete cell adhesion molecule activity	OBSOLETE. Mediates the adhesion of the cell to other cells or to the extracellular matrix.	got7fsn_ti	cell adhesion molecule activity				This term was made obsolete because it represents gene products involved in the biological process of cell adhesion.	GO:0016021|GO:0030246|GO:0050839|GO:0098631|GO:0005102|GO:0005515|GO:0007155				True				molecular_function											owl:Class	
GO:0032461	biolink:NamedThing	positive regulation of protein oligomerization	Any process that activates or increases the frequency, rate or extent of protein oligomerization.	got7fsn_ti	stimulation of protein oligomerization|activation of protein oligomerization|upregulation of protein oligomerization|induction of protein oligomerization|up-regulation of protein oligomerization|up regulation of protein oligomerization													biological_process											owl:Class	
GO:1901746	biolink:NamedThing	prephenate(2-) catabolic process	The chemical reactions and pathways resulting in the breakdown of prephenate(2-).	got7fsn_ti	prephenate catabolism|prephenate(2-) breakdown|prephenate(2-) degradation|prephenate breakdown|prephenate degradation|prephenate(2-) catabolism						yaf	2013-01-14T10:13:53Z						biological_process											owl:Class	
GO:1904388	biolink:NamedThing	negative regulation of ncRNA transcription associated with protein coding gene TSS/TES	Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES.	got7fsn_ti	negative regulation of pasRNA transcription|down regulation of ncRNA transcription associated with protein coding gene TSS/TES|down regulation of pasRNA transcription|down-regulation of ncRNA transcription associated with protein coding gene TSS/TES|downregulation of pasRNA transcription|down-regulation of pasRNA transcription|downregulation of ncRNA transcription associated with protein coding gene TSS/TES|inhibition of ncRNA transcription associated with protein coding gene TSS/TES|inhibition of pasRNA transcription						dos	2015-06-23T18:11:39Z						biological_process											owl:Class	
GO:0045853	biolink:NamedThing	negative regulation of bicoid mRNA localization	Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.	got7fsn_ti	down regulation of bicoid mRNA localization|down-regulation of bicoid mRNA localization|inhibition of bicoid mRNA localization|negative regulation of bicoid mRNA localisation|downregulation of bicoid mRNA localization													biological_process											owl:Class	
GO:1903884	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 20 production	Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.	got7fsn_ti	regulation of CCL20 production|regulation of C-C motif chemokine 20 production|regulation of CCL-20 production						krc	2015-02-06T16:31:02Z						biological_process											owl:Class	
GO:1905156	biolink:NamedThing	negative regulation of photosynthesis	Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis.	got7fsn_ti	down-regulation of photosynthesis|inhibition of photosynthesis|down regulation of photosynthesis|downregulation of photosynthesis						tb	2016-04-19T16:12:29Z						biological_process											owl:Class	
GO:0014736	biolink:NamedThing	negative regulation of muscle atrophy	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy.	got7fsn_ti														biological_process											owl:Class	
GO:1905578	biolink:NamedThing	regulation of ERBB3 signaling pathway	Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway.	got7fsn_ti	regulation of ERBB3 signalling pathway|regulation of HER3 signaling pathway|regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway						als	2016-10-19T11:46:55Z						biological_process											owl:Class	
GO:2001262	biolink:NamedThing	positive regulation of semaphorin-plexin signaling pathway	Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway.	got7fsn_ti	positive regulation of semaphorin-plexin signalling pathway						vk	2011-12-08T02:05:53Z						biological_process											owl:Class	
GO:2000336	biolink:NamedThing	negative regulation of endothelial microparticle formation	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation.	got7fsn_ti	negative regulation of endothelial microparticle release|negative regulation of endothelial microparticle generation						mah	2011-01-31T11:20:33Z						biological_process											owl:Class	
GO:2000705	biolink:NamedThing	regulation of dense core granule biogenesis	Any process that modulates the frequency, rate or extent of dense core granule biogenesis.	got7fsn_ti							yaf	2011-05-26T10:29:21Z						biological_process											owl:Class	
GO:1905043	biolink:NamedThing	positive regulation of epithelium regeneration	Any process that activates or increases the frequency, rate or extent of epithelium regeneration.	got7fsn_ti	up regulation of epithelium regeneration|activation of epithelium regeneration|positive regulation of regeneration of epithelium|upregulation of epithelium regeneration|up-regulation of epithelium regeneration|upregulation of regeneration of epithelium|up regulation of regeneration of epithelium|up-regulation of regeneration of epithelium|activation of regeneration of epithelium						rph	2016-03-11T10:59:12Z						biological_process											owl:Class	
GO:0010915	biolink:NamedThing	regulation of very-low-density lipoprotein particle clearance	Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti	regulation of VLDL clearance|regulation of VLDL particle clearance													biological_process											owl:Class	
GO:0030456	biolink:NamedThing	obsolete activation of MAPK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of MAPK (mating sensu Fungi)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:1900009	biolink:NamedThing	obsolete positive regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	OBSOLETE. Any process that activates or increases the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.	got7fsn_ti	up regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|up regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|up regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging|up regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.		se	2012-01-09T10:44:18Z		True				biological_process											owl:Class	
GO:1900949	biolink:NamedThing	positive regulation of isoprene biosynthetic process	Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process.	got7fsn_ti	activation of isoprene biosynthetic process|upregulation of isoprene biosynthetic process|up-regulation of 2-methyl-1,3-butadiene biosynthetic process|up regulation of hemiterpene biosynthetic process|up regulation of isoprene biosynthetic process|up-regulation of hemiterpene biosynthesis|positive regulation of hemiterpene biosynthetic process|upregulation of hemiterpene biosynthetic process|activation of hemiterpene biosynthetic process|up regulation of 2-methyl-1,3-butadiene biosynthetic process|up-regulation of hemiterpene biosynthetic process|upregulation of 2-methyl-1,3-butadiene biosynthesis|up-regulation of 2-methyl-1,3-butadiene biosynthesis|up regulation of 2-methyl-1,3-butadiene biosynthesis|upregulation of 2-methyl-1,3-butadiene biosynthetic process|up-regulation of isoprene biosynthetic process|activation of 2-methyl-1,3-butadiene biosynthetic process|activation of 2-methyl-1,3-butadiene biosynthesis|positive regulation of 2-methyl-1,3-butadiene biosynthetic process|positive regulation of hemiterpene biosynthesis|upregulation of hemiterpene biosynthesis|up regulation of hemiterpene biosynthesis|activation of hemiterpene biosynthesis|positive regulation of 2-methyl-1,3-butadiene biosynthesis						tt	2012-06-14T03:21:54Z						biological_process											owl:Class	
GO:0010398	biolink:NamedThing	xylogalacturonan metabolic process	The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues.	got7fsn_ti	xylogalacturonan metabolism													biological_process											owl:Class	
GO:0031351	biolink:NamedThing	integral component of plastid membrane	The component of the plastid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to plastid membrane													cellular_component											owl:Class	
GO:0052784	biolink:NamedThing	reuteran biosynthetic process	The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.	got7fsn_ti	reuteransucrase-mediated reuteran biosynthesis						ai	2011-10-04T09:20:35Z						biological_process											owl:Class	
GO:1905117	biolink:NamedThing	regulation of ribonucleoside-diphosphate reductase activity	Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.	got7fsn_ti	regulation of RNR|regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|regulation of class III ribonucleotide reductase activity|regulation of class II ribonucleoside-diphosphate reductase activity|regulation of nucleoside diphosphate reductase activity|regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|regulation of class I ribonucleotide reductase activity|regulation of ribonucleotide reductase activity|regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|regulation of class II ribonucleotide reductase activity|regulation of purine/pyrimidine nucleoside diphosphate reduction|regulation of ribonucleoside 5'-diphosphate reductase activity|regulation of ribonucleotide diphosphate reductase activity				An example of this is DRE2 in Saccharomyces cerevisiae (UniProt ID P36152) in PMID:24733891 (inferred from mutant phenotype).		bhm	2016-04-08T08:06:17Z						biological_process											owl:Class	
GO:1902785	biolink:NamedThing	cellular response to undecane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.	got7fsn_ti							tt	2014-03-21T13:39:24Z						biological_process											owl:Class	
GO:0002287	biolink:NamedThing	alpha-beta T cell activation involved in immune response	The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	alpha-beta T-lymphocyte activation during immune response|alpha-beta T lymphocyte activation during immune response|alpha-beta T-cell activation during immune response|alpha-beta T cell activation during immune response													biological_process											owl:Class	
GO:0009811	biolink:NamedThing	stilbene biosynthetic process	The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.	got7fsn_ti	stilbene formation|stilbene anabolism|stilbene biosynthesis|stilbene synthesis													biological_process											owl:Class	
GO:1903123	biolink:NamedThing	regulation of thioredoxin peroxidase activity	Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity.	got7fsn_ti	regulation of TPx activity|regulation of TrxPx activity|regulation of thiol peroxidase activity						bf	2014-06-18T11:03:11Z						biological_process											owl:Class	
GO:1903069	biolink:NamedThing	regulation of ER-associated ubiquitin-dependent protein catabolic process	Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.	got7fsn_ti	regulation of ER-associated protein catabolism|regulation of ER-associated protein breakdown|regulation of ER-associated protein degradation|regulation of ER-associated protein catabolic process|regulation of ERAD|regulation of endoplasmic reticulum-associated protein catabolism|regulation of endoplasmic reticulum-associated protein catabolic process						rph	2014-05-28T17:53:46Z						biological_process											owl:Class	
GO:0016355	biolink:NamedThing	obsolete DDT susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DDT susceptibility/resistance			GO:0046680	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:1903157	biolink:NamedThing	obsolete iron ion transmembrane transporter activity involved in iron ion import into cell	OBSOLETE. Any iron ion transmembrane transporter activity that is involved in iron ion import into cell.	got7fsn_ti	transmembrane iron permease activity involved in iron import into cell|multicopper ferroxidase iron transport mediator activity involved in iron ion import into cell|transmembrane iron ion permease activity involved in iron ion import into cell|transmembrane iron permease activity involved in iron ion import into cell|iron transporter activity involved in iron import into cell|iron transporter activity involved in iron ion import into cell|zinc, iron permease activity involved in iron import into cell|zinc, iron permease activity involved in iron ion import into cell|iron ion transmembrane transporter activity involved in iron import into cell|multicopper ferroxidase iron transport mediator activity involved in iron import into cell|iron ion transmembrane transporter activity involved in iron ion import into cell|transmembrane iron ion permease activity involved in iron import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:16Z		True				molecular_function											owl:Class	
GO:0000337	biolink:NamedThing	regulation of transposition, DNA-mediated	Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule.	got7fsn_ti	regulation of DNA transposition													biological_process											owl:Class	
GO:0006678	biolink:NamedThing	glucosylceramide metabolic process	The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.	got7fsn_ti	glucosylceramide metabolism													biological_process											owl:Class	
GO:1904985	biolink:NamedThing	negative regulation of quinolinate biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process.	got7fsn_ti	inhibition of quinolinate biosynthetic process|down regulation of quinolinate biosynthetic process|inhibition of quinolinate synthesis|down-regulation of quinolinate formation|down regulation of quinolinate anabolism|down-regulation of quinolinate biosynthetic process|negative regulation of quinolinate formation|down regulation of quinolinate formation|negative regulation of quinolinate anabolism|negative regulation of quinolinate synthesis|down-regulation of quinolinate anabolism|downregulation of quinolinate biosynthesis|downregulation of quinolinate anabolism|downregulation of quinolinate biosynthetic process|downregulation of quinolinate synthesis|inhibition of quinolinate biosynthesis|down regulation of quinolinate biosynthesis|down regulation of quinolinate synthesis|inhibition of quinolinate formation|down-regulation of quinolinate synthesis|down-regulation of quinolinate biosynthesis|downregulation of quinolinate formation|inhibition of quinolinate anabolism|negative regulation of quinolinate biosynthesis						bf	2016-02-29T15:54:21Z						biological_process											owl:Class	
UBERON:0001434	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903406	biolink:NamedThing	regulation of P-type sodium:potassium-exchanging transporter activity	Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.	got7fsn_ti	regulation of ATP phosphohydrolase (Na+/K+-exchanging)|regulation of Na+/K+-ATPase activity|regulation of Na,K-activated ATPase activity|regulation of Na(+)/K(+)-ATPase activity|regulation of sodium:potassium exchanging ATPase activity|regulation of (Na+ + K+)-activated ATPase activity|regulation of (Na+ + K+)-ATPase activity|regulation of Na+,K+ pump|regulation of Na,K-pump|regulation of Na+/K+-exchanging ATPase activity|regulation of sodium/potassium-exchanging ATPase activity|regulation of sodium/potassium-transporting ATPase activity|regulation of sodium:potassium-exchanging ATPase activity|regulation of sodium pump|regulation of Na+,K+-ATPase activity|regulation of Na(+)/K(+)-exchanging ATPase activity						mr	2014-09-02T19:45:08Z						biological_process											owl:Class	
GO:1904171	biolink:NamedThing	negative regulation of bleb assembly	Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly.	got7fsn_ti	down regulation of bleb assembly|downregulation of cell blebbing|inhibition of bleb assembly|down-regulation of bleb assembly|inhibition of cell blebbing|down regulation of cell blebbing|negative regulation of cell blebbing|down-regulation of cell blebbing|downregulation of bleb assembly						als	2015-04-23T09:32:25Z						biological_process											owl:Class	
GO:0097549	biolink:NamedThing	obsolete chromatin organization involved in negative regulation of transcription	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription by chromatin organization.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter, global by histone modification|negative regulation of transcription from Pol II promoter by histone modification|negative regulation of global transcription from Pol II promoter by histone modification|negative regulation of transcription by chromatin organization|negative regulation of transcription from RNA polymerase II promoter by histone modification|negative regulation of gene-specific transcription from RNA polymerase II promoter by histone modification	https://github.com/geneontology/go-ontology/issues/22041			This term was obsoleted because these it was redundant with other terms: heterochromatin assembly and negative regulation of gene expression, epigenetic.		pr	2014-01-22T08:20:50Z		True	GO:1903758			biological_process											owl:Class	
GO:1902307	biolink:NamedThing	positive regulation of sodium ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.	got7fsn_ti	activation of sodium ion transmembrane transport|activation of sodium ion membrane transport|up regulation of sodium ion transmembrane transport|positive regulation of sodium ion membrane transport|up regulation of sodium ion membrane transport|up-regulation of sodium ion transmembrane transport|upregulation of sodium ion membrane transport|up-regulation of sodium ion membrane transport|upregulation of sodium ion transmembrane transport						rl	2013-07-18T13:34:18Z						biological_process											owl:Class	
GO:0008153	biolink:NamedThing	para-aminobenzoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.	got7fsn_ti	4-aminobenzoic acid biosynthetic process|vitamin Bx biosynthesis|p-aminobenzoic acid biosynthesis|para-aminobenzoic acid anabolism|vitamin Bx biosynthetic process|p-aminobenzoic acid biosynthetic process|para-aminobenzoic acid biosynthesis|4-aminobenzoic acid biosynthesis|para-aminobenzoic acid formation|para-aminobenzoic acid synthesis|PABA biosynthesis|PABA biosynthetic process													biological_process											owl:Class	
GO:1901824	biolink:NamedThing	delta-carotene biosynthetic process	The chemical reactions and pathways resulting in the formation of delta-carotene.	got7fsn_ti	delta-carotene formation|delta-carotene biosynthesis|delta-carotene synthesis|delta-carotene anabolism						yaf	2013-01-22T11:17:38Z						biological_process											owl:Class	
GO:0034077	biolink:NamedThing	butanediol metabolic process	The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.	got7fsn_ti	butylene glycol metabolism|butylene glycol metabolic process|butanediol metabolism													biological_process											owl:Class	
GO:1990673	biolink:NamedThing	intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The component of the ERGIC membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic component of endoplasmic reticulum-Golgi intermediate compartment membrane						bhm	2015-03-02T11:44:46Z						cellular_component											owl:Class	
GO:0110142	biolink:NamedThing	ubiquinone biosynthesis complex	The cytosolic ubiquinone biosynthesis complex is composed of enzymes and accessory factors of the ubiquinone biosynthesis pathway and enables synthesis of the extremely hydrophobic molecule ubiquinone. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K.	got7fsn_ti	Ubi complex|CoQ metabolon						kmv	2019-04-25T15:48:21Z						cellular_component											owl:Class	
GO:1901348	biolink:NamedThing	positive regulation of secondary cell wall biogenesis	Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis.	got7fsn_ti	positive regulation of secondary cell wall formation|upregulation of secondary cell wall anabolism|activation of secondary cell wall synthesis|positive regulation of plant-type secondary cell wall biogenesis|up-regulation of secondary cell wall biosynthetic process|up-regulation of cellulose and pectin-containing secondary cell wall biogenesis|up-regulation of plant-type secondary cell wall biogenesis|up-regulation of secondary cell wall formation|activation of plant-type secondary cell wall biogenesis|positive regulation of secondary cell wall synthesis|activation of secondary cell wall biogenesis|activation of secondary cell wall anabolism|activation of cellulose and pectin-containing secondary cell wall biogenesis|up regulation of secondary cell wall formation|up-regulation of secondary cell wall anabolism|upregulation of secondary cell wall formation|up-regulation of secondary cell wall synthesis|activation of secondary cell wall formation|up regulation of secondary cell wall synthesis|upregulation of plant-type secondary cell wall biogenesis|up regulation of plant-type secondary cell wall biogenesis|positive regulation of secondary cell wall biosynthetic process|up regulation of secondary cell wall anabolism|upregulation of secondary cell wall biosynthetic process|positive regulation of secondary cell wall anabolism|upregulation of cellulose and pectin-containing secondary cell wall biogenesis|upregulation of secondary cell wall synthesis|up regulation of secondary cell wall biogenesis|up-regulation of secondary cell wall biogenesis|activation of secondary cell wall biosynthetic process|up regulation of cellulose and pectin-containing secondary cell wall biogenesis|upregulation of secondary cell wall biogenesis|up regulation of secondary cell wall biosynthetic process|positive regulation of cellulose and pectin-containing secondary cell wall biogenesis						tb	2012-09-07T17:59:14Z						biological_process											owl:Class	
GO:1905010	biolink:NamedThing	positive regulation of L-lysine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-lysine import into cell.	got7fsn_ti	positive regulation of L-lysine import into cell|up regulation of L-lysine import into cell|up-regulation of L-lysine import into cell|activation of L-lysine import into cell|upregulation of L-lysine import into cell						sl	2016-03-02T00:16:04Z						biological_process											owl:Class	
GO:1904868	biolink:NamedThing	telomerase catalytic core complex assembly	The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex.	got7fsn_ti	TERT-TERC complex assembly|telomerase catalytic core complex formation|TERT-TERC complex formation						rph	2015-12-18T10:02:45Z						biological_process											owl:Class	
GO:1900007	biolink:NamedThing	obsolete regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	OBSOLETE. Any process that modulates the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.	got7fsn_ti	regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|regulation of extrachromosomal rDNA circle accumulation during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.		se	2012-01-09T10:44:07Z		True				biological_process											owl:Class	
GO:0099587	biolink:NamedThing	inorganic ion import across plasma membrane	The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	inorganic ion import into cell													biological_process											owl:Class	
GO:0005193	biolink:NamedThing	obsolete major urinary protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	major urinary protein				This term was made obsolete because it describes presence in body fluids rather than an activity.					True				molecular_function											owl:Class	
GO:1902152	biolink:NamedThing	positive regulation of response to DNA integrity checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling.	got7fsn_ti	activation of response to signal involved in DNA integrity checkpoint|up regulation of DNA integrity checkpoint effector process|up regulation of response to DNA integrity checkpoint signaling|positive regulation of DNA integrity checkpoint effector process|up-regulation of response to DNA integrity checkpoint signaling|upregulation of response to signal involved in DNA integrity checkpoint|up-regulation of DNA integrity checkpoint effector process|positive regulation of response to signal involved in DNA integrity checkpoint|upregulation of response to DNA integrity checkpoint signaling|activation of response to DNA integrity checkpoint signaling|activation of DNA integrity checkpoint effector process|upregulation of DNA integrity checkpoint effector process|up-regulation of response to signal involved in DNA integrity checkpoint|up regulation of response to signal involved in DNA integrity checkpoint						jl	2013-05-21T15:44:31Z						biological_process											owl:Class	
GO:2000576	biolink:NamedThing	obsolete positive regulation of microtubule motor activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of microtubule motor activity.	got7fsn_ti	positive regulation of kinesin motor activity|positive regulation of axonemal motor activity|positive regulation of dynein ATPase activity|positive regulation of kinesin|positive regulation of kinetochore motor activity|positive regulation of dynein	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140660	bf	2011-04-05T08:36:51Z		True				biological_process											owl:Class	
GO:1900063	biolink:NamedThing	regulation of peroxisome organization	Any process that modulates the frequency, rate or extent of peroxisome organization.	got7fsn_ti	regulation of peroxisome organisation|regulation of peroxisome organization and biogenesis|regulation of peroxisome-assembly ATPase activity						dph	2012-01-26T01:49:05Z						biological_process											owl:Class	
GO:0070577	biolink:NamedThing	lysine-acetylated histone binding	Binding to a histone in which a lysine residue has been modified by acetylation.	got7fsn_ti	acetylated histone residue binding						mah	2009-04-21T03:03:35Z						molecular_function											owl:Class	
GO:1904507	biolink:NamedThing	positive regulation of telomere maintenance in response to DNA damage	Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.	got7fsn_ti	up regulation of DNA damage response, telomere maintenance|activation of telomere maintenance in response to DNA damage|up-regulation of telomere maintenance in response to DNA damage|upregulation of telomere maintenance in response to DNA damage|activation of DNA damage response, telomere maintenance|upregulation of DNA damage response, telomere maintenance|up-regulation of DNA damage response, telomere maintenance|up regulation of telomere maintenance in response to DNA damage|positive regulation of DNA damage response, telomere maintenance						nc	2015-07-24T16:06:09Z						biological_process											owl:Class	
GO:0007044	biolink:NamedThing	cell-substrate junction assembly	The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.	got7fsn_ti	cell-substrate adherens junction assembly				The primary label for merged term was 'cell-substrate adherens junction assembly' GO:0007045. The term was merged into the parent 'cell-substrate junction assembly', because, based on the most recent litarature, 'adherens junction' is always a 'cell-cell junction' (PMID:20571587, PMID:17854762, PMID:21422226, PMID:28096264, PMID:28401269, PMID:26923917).						GO:0007045			biological_process											owl:Class	
GO:0036043	biolink:NamedThing	obsolete microspike	OBSOLETE. A dynamic, actin-rich projection extending from the surface of a migrating animal cell.	got7fsn_ti	microspike			GO:0044393	This term was made obsolete because it accidentally reused an exisiting id. See replacement term GO:0044393.		bf	2011-12-06T01:31:16Z		True				cellular_component											owl:Class	
GO:0052247	biolink:NamedThing	obsolete positive energy taxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive energy taxis in other organism during symbiotic interaction|positive energy taxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1905413	biolink:NamedThing	regulation of dense core granule exocytosis	Any process that modulates the frequency, rate or extent of dense core granule exocytosis.	got7fsn_ti	regulation of dense core vesicle exocytosis						bf	2016-08-31T08:02:21Z						biological_process											owl:Class	
GO:1905534	biolink:NamedThing	positive regulation of leucine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane.	got7fsn_ti	up-regulation of L-leucine import into cell|activation of L-leucine import into cell|up-regulation of leucine import into cell|upregulation of leucine import into cell|up regulation of leucine import into cell|positive regulation of leucine import into cell|up regulation of L-leucine import into cell|positive regulation of L-leucine import into cell|activation of leucine import into cell|upregulation of L-leucine import into cell						vw	2014-06-25T13:10:04Z			GO:1903130			biological_process											owl:Class	
GO:0004184	biolink:NamedThing	obsolete lysine carboxypeptidase activity	OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma.	got7fsn_ti	peptidyl-L-lysine(-L-arginine) hydrolase|carboxypeptidase N activity|kininase I activity|hippuryllysine hydrolase activity|CPase N|creatinine kinase convertase activity|lysine carboxypeptidase activity|plasma carboxypeptidase B|kininase Ia|bradykinase activity|anaphylatoxin inactivator activity|lysine(arginine) carboxypeptidase activity|lysine (arginine) carboxypeptidase activity|arginine carboxypeptidase activity|creatine kinase conversion factor|bradykinin-decomposing enzyme			GO:0004181	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0006219	biolink:NamedThing	deoxyuridine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.	got7fsn_ti	deoxyuridine breakdown|deoxyuridine degradation|deoxyuridine catabolism													biological_process											owl:Class	
GO:0002706	biolink:NamedThing	regulation of lymphocyte mediated immunity	Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.	got7fsn_ti														biological_process											owl:Class	
GO:1901561	biolink:NamedThing	response to benomyl	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.	got7fsn_ti							mah	2012-11-02T15:32:33Z						biological_process											owl:Class	
GO:1902283	biolink:NamedThing	negative regulation of primary amine oxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity.	got7fsn_ti	down-regulation of primary amine oxidase activity|downregulation of amine oxidase (copper-containing) activity|down regulation of primary amine oxidase activity|downregulation of primary amine oxidase activity|down-regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|down-regulation of amine oxidase (copper-containing) activity|down regulation of amine oxidase (copper-containing) activity|down regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|inhibition of primary-amine:oxygen oxidoreductase (deaminating) activity|negative regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|downregulation of primary-amine:oxygen oxidoreductase (deaminating) activity|inhibition of amine oxidase (copper-containing) activity|inhibition of primary amine oxidase activity|negative regulation of amine oxidase (copper-containing) activity						ecu	2013-07-08T13:27:59Z						biological_process											owl:Class	
GO:2000501	biolink:NamedThing	regulation of natural killer cell chemotaxis	Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis.	got7fsn_ti							bf	2011-03-21T10:09:23Z						biological_process											owl:Class	
GO:0004007	biolink:NamedThing	obsolete heavy metal-exporting ATPase activity	OBSOLETE. Catalysis of the reaction: heavy metal ion(in) + ATP + H2O = heavy metal ion(out) + ADP + phosphate.	got7fsn_ti	heavy metal-exporting ATPase activity				This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0046873				True				molecular_function											owl:Class	
GO:0002157	biolink:NamedThing	positive regulation of thyroid hormone mediated signaling pathway	Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.	got7fsn_ti	positive regulation of thyroid hormone mediated signalling pathway						hjd	2009-11-19T12:42:57Z						biological_process											owl:Class	
GO:1901063	biolink:NamedThing	guaiacyl lignin biosynthetic process	The chemical reactions and pathways resulting in the formation of guaiacyl lignin.	got7fsn_ti	guaiacyl lignin formation|G-lignin biosynthetic process|guaiacyl lignin biosynthesis|guaiacyl lignin synthesis|guaiacyl lignin anabolism						tt	2012-06-29T03:29:53Z						biological_process											owl:Class	
GO:1905525	biolink:NamedThing	obsolete regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter in response to iron that results in regulation of ferrichrome biosynthetic process.	got7fsn_ti	regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron				This term was made obsolete because it was added in error.		al	2016-10-04T15:46:03Z		True				biological_process											owl:Class	
GO:1903148	biolink:NamedThing	obsolete uracil transmembrane transporter activity involved in uracil import into cell	OBSOLETE. Any uracil transmembrane transporter activity that is involved in uracil import into cell.	got7fsn_ti	uracil transmembrane transporter activity involved in uracil import into cell|uracil/uridine permease activity involved in uracil import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:24Z		True				molecular_function											owl:Class	
GO:0006667	biolink:NamedThing	sphinganine metabolic process	The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.	got7fsn_ti	sphinganine metabolism|dihydrosphingosine metabolism|dihydrosphingosine metabolic process													biological_process											owl:Class	
GO:0090052	biolink:NamedThing	regulation of pericentric heterochromatin assembly	Any process that modulates the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.	got7fsn_ti	regulation of chromatin silencing at centromere	https://github.com/geneontology/go-ontology/issues/19112					tb	2009-08-07T10:47:41Z						biological_process											owl:Class	
GO:0048698	biolink:NamedThing	negative regulation of collateral sprouting in absence of injury	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury.	got7fsn_ti	downregulation of collateral sprouting in the absence of injury|down regulation of collateral sprouting in the absence of injury|inhibition of collateral sprouting in the absence of injury|down-regulation of collateral sprouting in the absence of injury													biological_process											owl:Class	
GO:0046372	biolink:NamedThing	D-arabinose metabolic process	The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides.	got7fsn_ti	D-arabinose metabolism													biological_process											owl:Class	
GO:0055054	biolink:NamedThing	fructose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+.	got7fsn_ti	fructose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0045563	biolink:NamedThing	obsolete negative regulation of TRAIL receptor biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.	got7fsn_ti	downregulation of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor biosynthesis|down-regulation of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor anabolism|down regulation of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor synthesis|negative regulation of TRAIL receptor formation|inhibition of TRAIL receptor biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0097315	biolink:NamedThing	response to N-acetyl-D-glucosamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.	got7fsn_ti							pr	2012-05-30T03:58:54Z						biological_process											owl:Class	
GO:0002890	biolink:NamedThing	negative regulation of immunoglobulin mediated immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.	got7fsn_ti	inhibition of immunoglobulin mediated immune response|down-regulation of immunoglobulin mediated immune response|downregulation of immunoglobulin mediated immune response|down regulation of immunoglobulin mediated immune response													biological_process											owl:Class	
GO:0009685	biolink:NamedThing	gibberellin metabolic process	The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.	got7fsn_ti	gibberellic acid metabolic process|gibberellic acid metabolism|gibberellin metabolism													biological_process											owl:Class	
GO:1900705	biolink:NamedThing	negative regulation of siderophore biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process.	got7fsn_ti	negative regulation of siderochrome biosynthetic process|downregulation of siderophore biosynthesis|downregulation of siderophore formation|down-regulation of siderophore formation|downregulation of siderochrome biosynthesis|down regulation of siderophore synthesis|down-regulation of siderophore biosynthetic process, peptide modification|down-regulation of siderochrome biosynthesis|downregulation of siderophore synthesis|down-regulation of siderophore biosynthesis|negative regulation of siderochrome biosynthesis|down regulation of siderophore anabolism|down-regulation of siderophore anabolism|downregulation of siderophore biosynthetic process|negative regulation of siderophore synthesis|negative regulation of siderophore anabolism|down regulation of siderophore biosynthetic process|down regulation of siderophore biosynthetic process, peptide modification|negative regulation of siderophore biosynthetic process, peptide formation|negative regulation of siderophore formation|down regulation of siderophore biosynthesis|inhibition of siderophore biosynthesis|down-regulation of siderophore synthesis|inhibition of siderophore biosynthetic process, peptide modification|inhibition of siderophore formation|inhibition of siderophore synthesis|downregulation of siderophore anabolism|down regulation of siderophore biosynthetic process, peptide formation|down-regulation of siderophore biosynthetic process, peptide formation|downregulation of siderophore biosynthetic process, peptide modification|down regulation of siderochrome biosynthetic process|inhibition of siderophore biosynthetic process|inhibition of siderochrome biosynthetic process|downregulation of siderophore biosynthetic process, peptide formation|down regulation of siderophore formation|inhibition of siderophore anabolism|down-regulation of siderophore biosynthetic process|downregulation of siderochrome biosynthetic process|down-regulation of siderochrome biosynthetic process|inhibition of siderophore biosynthetic process, peptide formation|inhibition of siderochrome biosynthesis|negative regulation of siderophore biosynthetic process, peptide modification|down regulation of siderochrome biosynthesis|negative regulation of siderophore biosynthesis						di	2012-05-22T04:59:49Z						biological_process											owl:Class	
GO:1901620	biolink:NamedThing	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.	got7fsn_ti	regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning						krc	2012-11-13T20:11:57Z						biological_process											owl:Class	
GO:0006359	biolink:NamedThing	regulation of transcription by RNA polymerase III	Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.	got7fsn_ti	regulation of transcription from RNA polymerase III promoter|regulation of transcription from Pol III promoter													biological_process											owl:Class	
GO:2000981	biolink:NamedThing	negative regulation of inner ear receptor cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.	got7fsn_ti	negative regulation of inner ear hair cell differentiation						yaf	2011-08-03T02:38:47Z						biological_process											owl:Class	
GO:1902924	biolink:NamedThing	poly(hydroxyalkanoate) biosynthetic process from glucose	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose.	got7fsn_ti	poly(hydroxyalkanoate) formation from glucose|poly(hydroxyalkanoate) anabolism from glucose|poly(hydroxyalkanoate) biosynthesis from glucose|poly(hydroxyalkanoate) synthesis from glucose						tt	2014-04-21T22:49:07Z						biological_process											owl:Class	
GO:1901633	biolink:NamedThing	negative regulation of synaptic vesicle membrane organization	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization.	got7fsn_ti	downregulation of synaptic vesicle membrane organization and biogenesis|inhibition of SLMV biogenesis|downregulation of synaptic vesicle membrane organisation|inhibition of synaptic vesicle membrane organization and biogenesis|negative regulation of synaptic vesicle membrane organisation|downregulation of synaptic vesicle membrane organization|inhibition of synaptic vesicle membrane organisation|inhibition of synaptic vesicle membrane organization|negative regulation of synaptic vesicle membrane organization and biogenesis|down regulation of synaptic vesicle membrane organisation|down-regulation of SLMV biogenesis|negative regulation of SLMV biogenesis|downregulation of SLMV biogenesis|down-regulation of synaptic vesicle membrane organization and biogenesis|down regulation of SLMV biogenesis|down-regulation of synaptic vesicle membrane organisation|down-regulation of synaptic vesicle membrane organization|down regulation of synaptic vesicle membrane organization|down regulation of synaptic vesicle membrane organization and biogenesis						ans	2012-11-15T11:40:55Z						biological_process											owl:Class	
GO:0098521	biolink:NamedThing	inhibitory neuromuscular junction	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction.	got7fsn_ti					Inhibitory neuromuscular junctions are found in arthropods but not in vertebrates.		dos	2013-10-14T12:04:08Z						cellular_component											owl:Class	
GO:1990802	biolink:NamedThing	obsolete protein phosphorylation involved in DNA double-strand break processing	OBSOLETE. Any protein phosphorylation that is required for DNA double-strand break processing.	got7fsn_ti	protein amino acid phosphorylation involved in DNA double-strand break processing	https://github.com/geneontology/go-ontology/issues/14137			This term has been obsoleted because it represents a GO-CAM model.		rb	2015-07-16T20:43:39Z		True				biological_process											owl:Class	
GO:1900113	biolink:NamedThing	negative regulation of histone H3-K9 trimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation.	got7fsn_ti	down regulation of histone H3-K9 trimethylation|down-regulation of histone H3-K9 trimethylation|downregulation of histone H3-K9 trimethylation|inhibition of histone H3-K9 trimethylation						bf	2012-02-21T09:09:54Z						biological_process											owl:Class	
GO:0002876	biolink:NamedThing	positive regulation of chronic inflammatory response to antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.	got7fsn_ti	up regulation of chronic inflammatory response to antigenic stimulus|activation of chronic inflammatory response to antigenic stimulus|up-regulation of chronic inflammatory response to antigenic stimulus|stimulation of chronic inflammatory response to antigenic stimulus|upregulation of chronic inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:0052465	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont reactive oxygen species production	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont reactive oxygen intermediate production|modulation by organism of defense-related symbiont ROS production|modulation by organism of defense-related symbiont reactive oxygen species production|modulation by organism of defense-related symbiont AOS production|modulation by organism of defense-related symbiont metabolic burst|modulation by organism of defense-related symbiont respiratory burst|modulation by organism of defense-related symbiont active oxygen species production|modulation by organism of defense-related symbiont reactive oxidative species production|modulation by organism of defense-related symbiont oxidative burst|modulation by organism of defense-related symbiont ROI production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1905638	biolink:NamedThing	negative regulation of mitochondrial mRNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.	got7fsn_ti	downregulation of mitochondrial mRNA catabolic process|down-regulation of mitochondrial mRNA catabolic process|inhibition of mitochondrial mRNA catabolic process|down regulation of mitochondrial mRNA catabolic process						tb	2016-11-03T20:24:05Z						biological_process											owl:Class	
GO:1904672	biolink:NamedThing	regulation of somatic stem cell population maintenance	Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance.	got7fsn_ti							rph	2015-09-14T08:40:19Z						biological_process											owl:Class	
GO:0018914	biolink:NamedThing	chlorobenzene metabolic process	The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone.	got7fsn_ti	chlorobenzene metabolism											UM-BBD_pathwayID:cb		biological_process											owl:Class	
GO:1904474	biolink:NamedThing	cellular response to L-dopa	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.	got7fsn_ti							sl	2015-07-09T20:15:59Z						biological_process											owl:Class	
GO:0100065	biolink:NamedThing	obsolete negative regulation of leucine import by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates leucine import.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
CHEBI:32551	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905492	biolink:NamedThing	positive regulation of branching morphogenesis of a nerve	Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve.	got7fsn_ti	activation of branching morphogenesis of a nerve|up-regulation of branching morphogenesis of a nerve|up regulation of branching morphogenesis of a nerve|upregulation of branching morphogenesis of a nerve						hbye	2016-09-23T14:11:52Z						biological_process											owl:Class	
GO:0004274	biolink:NamedThing	obsolete dipeptidyl-peptidase IV activity	OBSOLETE. Catalysis of the release of an N-terminal dipeptide, by the hydrolysis of the Xbb-Xcc bond in Xaa-Xbb-Xcc, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline.	got7fsn_ti	glycoprotein GP110|dipeptidyl peptidase IV|leukocyte antigen CD26|lymphocyte antigen CD26|Xaa-Pro-dipeptidylaminopeptidase activity|pep X|dipeptidyl-aminopeptidase IV|X-PDAP|Gly-Pro naphthylamidase activity|dipeptidyl aminopeptidase IV activity|post-proline dipeptidyl aminopeptidase IV activity|postproline dipeptidyl aminopeptidase IV|DPP IV activity|glycylprolyl aminopeptidase activity|T cell triggering molecule Tp103|dipeptidyl-peptidase IV activity|glycylprolyl dipeptidylaminopeptidase activity|Xaa-Pro-dipeptidyl-aminopeptidase activity|amino acyl-prolyl dipeptidyl aminopeptidase activity|DPP IV/CD26|glycylproline aminopeptidase activity|dipeptidyl-peptide hydrolase activity				This term was made obsolete because it represents a gene product.	GO:0008236|GO:0008239				True		MetaCyc:3.4.14.5-RXN|EC:3.4.14.5		molecular_function											owl:Class	
GO:2000137	biolink:NamedThing	negative regulation of cell proliferation involved in heart morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.	got7fsn_ti							dph	2010-09-29T12:43:55Z						biological_process											owl:Class	
GO:1900372	biolink:NamedThing	negative regulation of purine nucleotide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.	got7fsn_ti	downregulation of purine nucleotide biosynthetic process|down regulation of purine nucleotide synthesis|down regulation of purine nucleotide biosynthetic process|negative regulation of purine nucleotide synthesis|down regulation of purine nucleotide anabolism|down-regulation of purine nucleotide formation|down regulation of purine nucleotide biosynthesis|downregulation of purine nucleotide anabolism|down regulation of purine nucleotide formation|negative regulation of purine nucleotide formation|downregulation of purine nucleotide synthesis|downregulation of purine nucleotide formation|downregulation of purine nucleotide biosynthesis|negative regulation of purine nucleotide anabolism|inhibition of purine nucleotide formation|negative regulation of purine nucleotide biosynthesis|down-regulation of purine nucleotide anabolism|inhibition of purine nucleotide synthesis|down-regulation of purine nucleotide biosynthesis|inhibition of purine nucleotide anabolism|down-regulation of purine nucleotide synthesis|inhibition of purine nucleotide biosynthetic process|down-regulation of purine nucleotide biosynthetic process|inhibition of purine nucleotide biosynthesis						krc	2012-04-17T12:32:27Z						biological_process											owl:Class	
GO:1902787	biolink:NamedThing	cellular response to dodecane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.	got7fsn_ti							tt	2014-03-21T13:41:52Z						biological_process											owl:Class	
GO:1905669	biolink:NamedThing	TORC1 complex assembly	The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex.	got7fsn_ti	TORC1 assembly|TOR complex 1 formation|TORC1 formation|mTORC1 assembly|TORC1 complex formation|dTOR/dRaptor complex formation|dTORC1 assembly|rapamycin and nutrient-sensitive TOR complex formation|rapamycin and nutrient-sensitive TOR complex assembly|mTORC1 formation|nutrient sensitive complex formation|dTORC1 formation|TOR complex 1 assembly|TORC 1 complex formation|TORC 1 complex assembly|dTOR/dRaptor complex assembly|nutrient sensitive complex assembly						kmv	2016-11-11T21:03:27Z						biological_process											owl:Class	
GO:1905384	biolink:NamedThing	regulation of protein localization to presynapse	Any process that modulates the frequency, rate or extent of protein localization to presynapse.	got7fsn_ti	regulation of recruitment of presynaptic proteins|regulation of protein localisation in presynapse|regulation of protein localization in presynapse|regulation of protein localisation to presynapse						dos	2016-08-18T14:56:00Z						biological_process											owl:Class	
GO:1905339	biolink:NamedThing	positive regulation of cohesin unloading	Any process that activates or increases the frequency, rate or extent of cohesin unloading.	got7fsn_ti	up-regulation of cohesin unloading|activation of cohesin unloading|up regulation of cohesin unloading|upregulation of cohesin unloading						vw	2016-07-26T16:24:06Z						biological_process											owl:Class	
GO:0004196	biolink:NamedThing	obsolete saccharopepsin activity	OBSOLETE. Catalysis of the degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than pepsin A; does not cleave Phe1-Val2, Gln4-His5 or Gly23-Phe24.	got7fsn_ti	Saccharomyces aspartic proteinase activity|saccharopepsin activity|saccharomyces cerevisiae aspartic proteinase A|proteinase yscA|yeast endopeptidase A activity|aspartic proteinase yscA|saccharomyces aspartic proteinase activity|proteinase A|PRA|yeast proteinase A			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0045971	biolink:NamedThing	positive regulation of juvenile hormone catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.	got7fsn_ti	positive regulation of juvenile hormone breakdown|upregulation of juvenile hormone catabolic process|stimulation of juvenile hormone catabolic process|positive regulation of juvenile hormone catabolism|activation of juvenile hormone catabolic process|positive regulation of juvenile hormone degradation|up-regulation of juvenile hormone catabolic process|up regulation of juvenile hormone catabolic process													biological_process											owl:Class	
GO:0071733	biolink:NamedThing	obsolete transcriptional activation by promoter-enhancer looping	OBSOLETE. The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.	got7fsn_ti	long-range enhancer-promoter communication	https://github.com/geneontology/go-ontology/issues/20204			This term was obsoleted because it was defined like a molecular function.	GO:0045893	mah	2010-03-19T02:01:19Z		True				biological_process											owl:Class	
GO:0006609	biolink:NamedThing	obsolete mRNA-binding (hnRNP) protein import into nucleus	OBSOLETE. The directed movement of a heterogeneous nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane.	got7fsn_ti	mRNA-binding (hnRNP) protein-nucleus import|mRNA-binding (hnRNP) protein transport from cytoplasm to nucleus|mRNA-binding (hnRNP) protein import into cell nucleus				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606				True				biological_process											owl:Class	
GO:2000109	biolink:NamedThing	regulation of macrophage apoptotic process	Any process that modulates the frequency, rate or extent of macrophage apoptotic process.	got7fsn_ti	regulation of AICD|regulation of activation-induced cell death|regulation of macrophage apoptosis						mah	2010-09-15T01:44:15Z						biological_process											owl:Class	
GO:0003078	biolink:NamedThing	obsolete regulation of natriuresis	OBSOLETE. Any process that modulates the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.	got7fsn_ti	regulation of natriuresis				This term was made obsolete because its definition was inaccurate.	GO:0035813				True				biological_process											owl:Class	
GO:1901843	biolink:NamedThing	positive regulation of high voltage-gated calcium channel activity	Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.	got7fsn_ti	upregulation of high voltage-gated calcium channel activity|up-regulation of high voltage-dependent calcium channel activity|activation of high voltage-gated calcium channel activity|up-regulation of high voltage gated calcium channel activity|up regulation of high voltage-dependent calcium channel activity|positive regulation of high voltage gated calcium channel activity|up regulation of high voltage-gated calcium channel activity|positive regulation of high voltage-dependent calcium channel activity|upregulation of high voltage-dependent calcium channel activity|activation of high voltage-dependent calcium channel activity|activation of high voltage gated calcium channel activity|up-regulation of high voltage-gated calcium channel activity|upregulation of high voltage gated calcium channel activity|up regulation of high voltage gated calcium channel activity						rl	2013-01-24T19:02:25Z						biological_process											owl:Class	
GO:0075067	biolink:NamedThing	obsolete growth or development of symbiont in host intercellular space	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's intercellular space. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of symbiont in host intercellular space				This term was made obsolete because it contained a conjunction (or).	GO:0051701|GO:0044114				True				biological_process											owl:Class	
GO:1902028	biolink:NamedThing	regulation of histone H3-K18 acetylation	Any process that modulates the frequency, rate or extent of histone H3-K18 acetylation.	got7fsn_ti	regulation of histone H3 acetylation at K18|regulation of histone H3K18 acetylation						jl	2013-03-28T20:17:39Z						biological_process											owl:Class	
GO:1900739	biolink:NamedThing	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.	got7fsn_ti	regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|regulation of protein insertion into mitochondrion membrane during induction of apoptosis|regulation of protein insertion into mitochondrial membrane during induction of apoptosis|regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis						pr	2012-05-28T02:28:18Z						biological_process											owl:Class	
GO:0031939	biolink:NamedThing	obsolete negative regulation of chromatin silencing at telomere	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres.	got7fsn_ti	down-regulation of chromatin silencing at telomere|inhibition of chromatin silencing at telomere|downregulation of chromatin silencing at telomere|down regulation of chromatin silencing at telomere|negative regulation of heterochromatic silencing at telomere	https://github.com/geneontology/go-ontology/issues/22027			This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.					True				biological_process											owl:Class	
GO:0140661	biolink:NamedThing	cytoskeletal motor inhibitor activity	Binds to and stops, prevents, or reduces the activity of a motor protein.	got7fsn_ti	motor activity inhibitor activity	https://github.com/geneontology/go-ontology/issues/21756|https://github.com/geneontology/go-ontology/issues/21627					pg	2021-06-16T11:22:54Z						molecular_function											owl:Class	
GO:0015050	biolink:NamedThing	methane monooxygenase complex	A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.	got7fsn_ti														cellular_component											owl:Class	
GO:1902889	biolink:NamedThing	protein localization to spindle microtubule	A process in which a protein is transported to, or maintained in, a location within a spindle microtubule.	got7fsn_ti	protein localisation in spindle microtubule|protein localization in spindle microtubule|protein localisation to spindle microtubule						kmv	2014-04-05T21:31:39Z						biological_process											owl:Class	
GO:1903026	biolink:NamedThing	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.	got7fsn_ti	down-regulation of RNA polymerase II regulatory region sequence-specific DNA binding|downregulation of RNA polymerase II regulatory region sequence-specific DNA binding|down regulation of RNA polymerase II regulatory region sequence-specific DNA binding|inhibition of RNA polymerase II regulatory region sequence-specific DNA binding						dph	2014-05-15T17:56:00Z						biological_process											owl:Class	
GO:0016101	biolink:NamedThing	diterpenoid metabolic process	The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.	got7fsn_ti	diterpene metabolism|diterpene metabolic process|diterpenoid metabolism													biological_process											owl:Class	
GO:1901195	biolink:NamedThing	positive regulation of formation of translation preinitiation complex	Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex.	got7fsn_ti	activation of formation of translation pre-initiation complex|positive regulation of formation of translation pre-initiation complex|upregulation of formation of translation pre-initiation complex|upregulation of translation preinitiation complex assembly|activation of formation of translation preinitiation complex|activation of translation preinitiation complex assembly|up regulation of translation preinitiation complex assembly|up-regulation of translation preinitiation complex assembly|upregulation of formation of translation preinitiation complex|positive regulation of translation preinitiation complex assembly|up-regulation of formation of translation pre-initiation complex|up regulation of formation of translation pre-initiation complex|up-regulation of formation of translation preinitiation complex|up regulation of formation of translation preinitiation complex						ss	2012-07-25T02:31:50Z						biological_process											owl:Class	
GO:0009233	biolink:NamedThing	menaquinone metabolic process	The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.	got7fsn_ti	menatetrenone metabolic process|vitamin K2 metabolism|menaquinone metabolism|multiprenylmenaquinone metabolism|multiprenylmenaquinone metabolic process|menatetrenone metabolism|vitamin K2 metabolic process													biological_process											owl:Class	
GO:0046348	biolink:NamedThing	amino sugar catabolic process	The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group.	got7fsn_ti	amino sugar breakdown|aminosaccharide catabolism|amino sugar degradation|aminosaccharide catabolic process|amino sugar catabolism													biological_process											owl:Class	
GO:0120270	biolink:NamedThing	regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18757					krc	2020-10-08T20:52:55Z						biological_process											owl:Class	
GO:1902394	biolink:NamedThing	positive regulation of exodeoxyribonuclease activity	Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity.	got7fsn_ti	activation of exodeoxyribonuclease activity|up-regulation of exodeoxyribonuclease activity|upregulation of exodeoxyribonuclease activity|up regulation of exodeoxyribonuclease activity						jl	2013-09-11T14:56:38Z						biological_process											owl:Class	
GO:0032967	biolink:NamedThing	positive regulation of collagen biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	got7fsn_ti	positive regulation of collagen synthesis|positive regulation of collagen anabolism|positive regulation of collagen formation|positive regulation of collagen biosynthesis													biological_process											owl:Class	
GO:1904098	biolink:NamedThing	regulation of protein O-linked glycosylation	Any process that modulates the frequency, rate or extent of protein O-linked glycosylation.	got7fsn_ti	regulation of protein amino acid O-linked glycosylation						krc	2015-03-27T16:09:58Z						biological_process											owl:Class	
GO:1901267	biolink:NamedThing	cephalosporin C catabolic process	The chemical reactions and pathways resulting in the breakdown of cephalosporin C.	got7fsn_ti	cephalosporin C degradation|cephalosporin C catabolism|cephalosporin C breakdown						yaf	2012-08-17T14:26:19Z						biological_process											owl:Class	
GO:1902523	biolink:NamedThing	positive regulation of protein K63-linked ubiquitination	Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination.	got7fsn_ti	upregulation of protein K63-linked ubiquitination|activation of protein K63-linked ubiquitination|activation of protein K63-linked polyubiquitination|positive regulation of protein K63-linked polyubiquitination|up-regulation of protein K63-linked ubiquitination|up-regulation of protein K63-linked polyubiquitination|up regulation of protein K63-linked polyubiquitination|upregulation of protein K63-linked polyubiquitination|up regulation of protein K63-linked ubiquitination				An example is BIRC2 (UniProt ID Q13490) in PMID:21931591.		ppm	2013-12-02T09:52:05Z						biological_process											owl:Class	
GO:0048690	biolink:NamedThing	regulation of axon extension involved in regeneration	Any process that modulates the frequency, rate or extent of axon extension involved in regeneration.	got7fsn_ti														biological_process											owl:Class	
GO:0048330	biolink:NamedThing	positive regulation of axial mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification.	got7fsn_ti	activation of axial mesodermal cell fate specification|stimulation of axial mesodermal cell fate specification|up regulation of axial mesodermal cell fate specification|up-regulation of axial mesodermal cell fate specification|upregulation of axial mesodermal cell fate specification													biological_process											owl:Class	
GO:0150111	biolink:NamedThing	regulation of transepithelial transport	Any process that modulates the frequency, rate or extent of transepithelial transport.	got7fsn_ti							bc	2019-09-15T07:16:49Z						biological_process											owl:Class	
GO:2000185	biolink:NamedThing	regulation of phosphate transmembrane transport	Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.	got7fsn_ti	regulation of phosphate membrane transport						vw	2010-10-15T11:33:04Z						biological_process											owl:Class	
GO:0008546	biolink:NamedThing	obsolete microtubule/chromatin interaction	OBSOLETE. Physical interaction between microtubules and chromatin via DNA binding proteins.	got7fsn_ti	microtubule/chromatin interaction				This term was made obsolete because it represents a molecular function.	GO:0030674|GO:0003682|GO:0008017|GO:0003677				True				biological_process											owl:Class	
GO:1902899	biolink:NamedThing	fatty acid methyl ester biosynthetic process	The chemical reactions and pathways resulting in the formation of fatty acid methyl ester.	got7fsn_ti	FAME biosynthetic process|fatty acid methyl ester synthesis|fatty acid methyl ester biosynthesis|fatty acid methyl ester formation|fatty acid methyl ester anabolism						tt	2014-04-11T03:08:40Z						biological_process											owl:Class	
GO:0031596	biolink:NamedThing	obsolete ER proteasome complex	OBSOLETE. A proteasome found in the endoplasmic reticulum of a cell.	got7fsn_ti					This term was made obsolete because there is no evidence in the literature of its existence.					True				cellular_component											owl:Class	
GO:0052002	biolink:NamedThing	obsolete metabolism by symbiont of substance in host	OBSOLETE. The chemical reactions and pathways performed by an organism in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:2000764	biolink:NamedThing	positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis.	got7fsn_ti	positive regulation of semaphorin-plexin signalling pathway involved in outflow tract morphogenesis						vk	2011-06-18T04:26:00Z						biological_process											owl:Class	
GO:0005708	biolink:NamedThing	obsolete mitotic chromosome	OBSOLETE. A chromosome involved in the process of mitosis.	got7fsn_ti	mitotic chromosome				This term was made obsolete because it is based on a process.	GO:0000794|GO:0000793				True				cellular_component											owl:Class	
GO:0010539	biolink:NamedThing	obsolete Hsp27 protein inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the Hsp27 molecular chaperone.	got7fsn_ti	Hsp27 protein inhibitor activity			GO:0051008	This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp27 protein activity'.	GO:0006457|GO:0051082|GO:0051787				True				molecular_function											owl:Class	
GO:1900323	biolink:NamedThing	positive regulation of maltotetraose transport	Any process that activates or increases the frequency, rate or extent of maltotetraose transport.	got7fsn_ti	upregulation of maltotetraose transport|up-regulation of maltotetraose transport|activation of maltotetraose transport|up regulation of maltotetraose transport						tt	2012-04-06T01:45:54Z						biological_process											owl:Class	
GO:0060782	biolink:NamedThing	regulation of mesenchymal cell proliferation involved in prostate gland development	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	got7fsn_ti							dph	2009-07-28T11:54:20Z						biological_process											owl:Class	
GO:0042280	biolink:NamedThing	obsolete cell surface antigen activity, host-interacting	OBSOLETE. Functions as an immunogenic target for the host immune system that masks other invariant surface molecules from immune recognition.	got7fsn_ti	cell surface antigen activity, host-interacting				This term was made obsolete because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.	GO:0046789|GO:0044403				True				molecular_function											owl:Class	
GO:0002624	biolink:NamedThing	positive regulation of B cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.	got7fsn_ti	upregulation of B cell antigen processing and presentation|stimulation of B cell antigen processing and presentation|positive regulation of B-lymphocyte antigen processing and presentation|positive regulation of B-cell antigen processing and presentation|positive regulation of B lymphocyte antigen processing and presentation|up-regulation of B cell antigen processing and presentation|activation of B cell antigen processing and presentation|up regulation of B cell antigen processing and presentation													biological_process											owl:Class	
GO:1903828	biolink:NamedThing	negative regulation of cellular protein localization	Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.	got7fsn_ti	down regulation of cellular protein localisation|down-regulation of channel localizer activity|inhibition of cellular protein localisation|inhibition of cellular protein localization|inhibition of channel localizer activity|downregulation of channel localizer activity|down regulation of cellular protein localization|down-regulation of cellular protein localisation|down regulation of channel localizer activity|downregulation of cellular protein localisation|negative regulation of cellular protein localisation|down-regulation of cellular protein localization|downregulation of cellular protein localization|negative regulation of channel localizer activity						jl	2015-01-20T14:32:24Z						biological_process											owl:Class	
GO:0120059	biolink:NamedThing	negative regulation of small intestinal transit	Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.	got7fsn_ti	negative regulation of small intestine transit|negative regulation of small bowel transit						krc	2017-06-13T20:58:23Z						biological_process											owl:Class	
GO:1901842	biolink:NamedThing	negative regulation of high voltage-gated calcium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity.	got7fsn_ti	down regulation of high voltage gated calcium channel activity|downregulation of high voltage gated calcium channel activity|negative regulation of high voltage-dependent calcium channel activity|down-regulation of high voltage-gated calcium channel activity|downregulation of high voltage-dependent calcium channel activity|down-regulation of high voltage gated calcium channel activity|negative regulation of high voltage gated calcium channel activity|down regulation of high voltage-dependent calcium channel activity|inhibition of high voltage gated calcium channel activity|down-regulation of high voltage-dependent calcium channel activity|inhibition of high voltage-gated calcium channel activity|inhibition of high voltage-dependent calcium channel activity|downregulation of high voltage-gated calcium channel activity|down regulation of high voltage-gated calcium channel activity						rl	2013-01-24T19:02:20Z						biological_process											owl:Class	
GO:0018903	biolink:NamedThing	1,3-dichloropropene metabolic process	The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes.	got7fsn_ti	1,3-dichloropropylene metabolism|gamma-chloroallylchloride metabolic process|1,3-dichloropropene metabolism|gamma-chloroallylchloride metabolism|1,3-dichloropropylene metabolic process											UM-BBD_pathwayID:cpr		biological_process											owl:Class	
GO:0090260	biolink:NamedThing	negative regulation of retinal ganglion cell axon guidance	Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.	got7fsn_ti	axon growth cone collapse				Note that growth cone collapse has been observed only in assays performed in vitro.		tb	2010-02-03T04:13:59Z						biological_process											owl:Class	
GO:1902274	biolink:NamedThing	positive regulation of (R)-carnitine transmembrane transport	Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport.	got7fsn_ti	up-regulation of (R)-carnitine transmembrane transport|upregulation of (R)-carnitine transmembrane transport|activation of (R)-carnitine transmembrane transport|up regulation of (R)-carnitine transmembrane transport						mcc	2013-07-01T13:13:22Z						biological_process											owl:Class	
GO:1903056	biolink:NamedThing	regulation of melanosome organization	Any process that modulates the frequency, rate or extent of melanosome organization.	got7fsn_ti	regulation of melanosome organisation|regulation of melanosome organization and biogenesis				Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles		rl	2014-05-27T13:27:49Z						biological_process											owl:Class	
GO:2000372	biolink:NamedThing	negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.	got7fsn_ti	negative regulation of type II DNA topoisomerase activity|negative regulation of DNA topoisomerase (ATP-hydrolysing)|negative regulation of topoisomerase|negative regulation of DNA topoisomerase IV activity|negative regulation of deoxyribonucleate topoisomerase|negative regulation of DNA topoisomerase type II activity|negative regulation of DNA topoisomerase II|negative regulation of deoxyribonucleic topoisomerase activity|negative regulation of topoisomerase II						mah	2011-02-09T02:35:36Z						biological_process											owl:Class	
GO:1903643	biolink:NamedThing	positive regulation of recombination hotspot binding	Any process that activates or increases the frequency, rate or extent of recombination hotspot binding.	got7fsn_ti	activation of DNA binding, recombination hotspot|up regulation of DNA binding, recombination hotspot|upregulation of recombination hotspot binding|upregulation of DNA binding, recombination hotspot|positive regulation of DNA binding, recombination hotspot|activation of recombination hotspot binding|up regulation of recombination hotspot binding|up-regulation of recombination hotspot binding|up-regulation of DNA binding, recombination hotspot						al	2014-11-21T12:02:31Z						biological_process											owl:Class	
GO:1901957	biolink:NamedThing	regulation of cutin biosynthetic process	Any process that modulates the frequency, rate or extent of cutin biosynthetic process.	got7fsn_ti	regulation of cutin biosynthesis|regulation of cutin synthesis|regulation of cutin formation|regulation of cutin anabolism						tb	2013-02-19T19:06:06Z						biological_process											owl:Class	
GO:1903578	biolink:NamedThing	regulation of ATP metabolic process	Any process that modulates the frequency, rate or extent of ATP metabolic process.	got7fsn_ti	regulation of ATP metabolism						sl	2014-10-30T19:04:24Z						biological_process											owl:Class	
GO:1901763	biolink:NamedThing	oxytetracycline biosynthetic process	The chemical reactions and pathways resulting in the formation of oxytetracycline.	got7fsn_ti	oxytetracycline formation|oxytetracycline biosynthesis|oxytetracycline anabolism|oxytetracycline synthesis						yaf	2013-01-15T09:52:59Z						biological_process											owl:Class	
GO:0060599	biolink:NamedThing	lateral sprouting involved in mammary gland duct morphogenesis	The process in which a branch forms along the side of a mammary duct.	got7fsn_ti	mammary gland duct secondary branching						dph	2009-05-13T12:38:06Z						biological_process											owl:Class	
GO:1900131	biolink:NamedThing	negative regulation of lipid binding	Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.	got7fsn_ti	downregulation of lipid binding|inhibition of lipid binding|down regulation of lipid binding|down-regulation of lipid binding						pm	2012-02-23T04:05:07Z						biological_process											owl:Class	
GO:1905760	biolink:NamedThing	post-anaphase array microtubule end	Any microtubule end that is part of a post-anaphase array microtubule.	got7fsn_ti	microtubule end of microtubulus of post-anaphase microtubule array|microtubule end of microtubuli of post-anaphase array|microtubule end of microtubuli of post-anaphase microtubule array|microtubule end of microtubulus of post-anaphase array|microtubule end of microtubuli of PAA|microtubule end of post-anaphase array microtubule|microtubule end of microtubule of post-anaphase array|microtubule end of microtubulus of PAA|microtubule end of neurotubule of post-anaphase array|microtubule end of neurotubule of post-anaphase microtubule array|microtubule end of microtubule of post-anaphase microtubule array|microtubule end of microtubule of PAA|microtubule end of neurotubule of PAA						dos	2016-12-12T19:38:32Z						cellular_component											owl:Class	
GO:0042836	biolink:NamedThing	D-glucarate metabolic process	The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose.	got7fsn_ti	saccharate metabolic process|D-glucarate metabolism|saccharate metabolism													biological_process											owl:Class	
GO:0070232	biolink:NamedThing	regulation of T cell apoptotic process	Any process that modulates the occurrence or rate of T cell death by apoptotic process.	got7fsn_ti	regulation of T lymphocyte apoptosis|regulation of programmed cell death of T cells by apoptosis|regulation of T cell apoptosis|regulation of T-cell apoptosis|regulation of T-lymphocyte apoptosis													biological_process											owl:Class	
GO:0009149	biolink:NamedThing	pyrimidine nucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside triphosphate breakdown|pyrimidine nucleoside triphosphate catabolism|pyrimidine nucleoside triphosphate degradation													biological_process											owl:Class	
GO:1900289	biolink:NamedThing	negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.	got7fsn_ti	negative regulation of coenzyme F420-dependent nitroimidazole reduction|inhibition of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent nitroimidazole breakdown|negative regulation of coenzyme F420-dependent nitroimidazole catabolism|downregulation of coenzyme F420-dependent nitroimidazole catabolism|down regulation of coenzyme F420-dependent nitroreductase activity|inhibition of coenzyme F420-dependent nitroimidazole reduction|inhibition of coenzyme F420-dependent nitroreductase activity|down regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|inhibition of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|downregulation of coenzyme F420-dependent nitroimidazole reduction|negative regulation of coenzyme F420-dependent nitroreductase activity|down-regulation of coenzyme F420-dependent nitroimidazole reduction|downregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|down regulation of coenzyme F420-dependent nitroimidazole reduction|downregulation of coenzyme F420-dependent nitroreductase activity|down-regulation of coenzyme F420-dependent nitroimidazole catabolism|inhibition of coenzyme F420-dependent nitroimidazole catabolism|down-regulation of coenzyme F420-dependent nitroreductase activity|negative regulation of coenzyme F420-dependent nitroimidazole breakdown|downregulation of coenzyme F420-dependent nitroimidazole breakdown|down-regulation of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent nitroimidazole catabolism|down-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process						tt	2012-04-05T06:02:51Z						biological_process											owl:Class	
GO:0098694	biolink:NamedThing	regulation of synaptic vesicle budding from presynaptic endocytic zone membrane	Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane.	got7fsn_ti							dos	2017-04-04T17:03:29Z						biological_process											owl:Class	
GO:1900209	biolink:NamedThing	negative regulation of cardiolipin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process.	got7fsn_ti	down regulation of diphosphatidylglycerol metabolic process|down regulation of diphosphatidylglycerol metabolism|down-regulation of diphosphatidylglycerol metabolism|down regulation of cardiolipin metabolic process|downregulation of diphosphatidylglycerol metabolism|inhibition of diphosphatidylglycerol metabolism|down-regulation of cardiolipin metabolism|negative regulation of cardiolipin metabolism|downregulation of diphosphatidylglycerol metabolic process|down regulation of cardiolipin metabolism|inhibition of diphosphatidylglycerol metabolic process|down-regulation of diphosphatidylglycerol metabolic process|inhibition of cardiolipin metabolic process|negative regulation of diphosphatidylglycerol metabolic process|down-regulation of cardiolipin metabolic process|downregulation of cardiolipin metabolism|downregulation of cardiolipin metabolic process|negative regulation of diphosphatidylglycerol metabolism|inhibition of cardiolipin metabolism						jl	2012-03-22T10:43:43Z						biological_process											owl:Class	
GO:0018192	biolink:NamedThing	obsolete enzyme active site formation via cysteine modification to L-cysteine persulfide	OBSOLETE. The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide.	got7fsn_ti	enzyme active site formation via L-cysteine persulphide	https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:11592406.	GO:0004792				True				biological_process											owl:Class	
GO:0045966	biolink:NamedThing	positive regulation of ecdysteroid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids.	got7fsn_ti	activation of ecdysteroid metabolic process|up-regulation of ecdysteroid metabolic process|positive regulation of ecdysteroid metabolism|up regulation of ecdysteroid metabolic process|upregulation of ecdysteroid metabolic process|stimulation of ecdysteroid metabolic process													biological_process											owl:Class	
GO:1902802	biolink:NamedThing	regulation of heterochromatin domain assembly	Any process that modulates the frequency, rate or extent of heterochromatin domain assembly.	got7fsn_ti	regulation of HOOD formation|regulation of HOOD assembly|regulation of heterochromatin domain formation						mah	2014-03-25T14:44:54Z						biological_process											owl:Class	
GO:0052649	biolink:NamedThing	coenzyme gamma-F420-2 metabolic process	The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid.	got7fsn_ti	F420-2 metabolism|coenzyme gamma-F420-2 metabolism|coenzyme F420 metabolism|F420-2 metabolic process|coenzyme F420 metabolic process						ai	2010-09-22T04:32:35Z						biological_process											owl:Class	
GO:0042558	biolink:NamedThing	pteridine-containing compound metabolic process	The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.	got7fsn_ti	pteridine and derivative metabolic process|pterin metabolic process|pteridine-containing compound metabolism|pterin metabolism|pteridine and derivative metabolism										GO:0019721			biological_process											owl:Class	
GO:1903556	biolink:NamedThing	negative regulation of tumor necrosis factor superfamily cytokine production	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.	got7fsn_ti	downregulation of tumor necrosis factor superfamily cytokine production|down-regulation of tumor necrosis factor superfamily cytokine production|down-regulation of TNFSF cytokine production|down regulation of tumor necrosis factor superfamily cytokine production|inhibition of TNF superfamily production|downregulation of TNF superfamily production|downregulation of TNFSF cytokine production|down regulation of TNFSF cytokine production|negative regulation of TNF superfamily production|down regulation of TNF superfamily production|inhibition of tumor necrosis factor superfamily cytokine production|inhibition of TNFSF cytokine production|negative regulation of TNFSF cytokine production|down-regulation of TNF superfamily production						pga	2014-10-21T10:26:14Z						biological_process											owl:Class	
GO:2001279	biolink:NamedThing	regulation of unsaturated fatty acid biosynthetic process	Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process.	got7fsn_ti	regulation of unsaturated fatty acid formation|regulation of polyunsaturated fatty acid biosynthesis|regulation of unsaturated fatty acid anabolism|regulation of unsaturated fatty acid synthesis|regulation of fatty acid desaturation|regulation of unsaturated fatty acid biosynthesis						dgf	2011-12-14T07:48:26Z						biological_process											owl:Class	
GO:1905524	biolink:NamedThing	negative regulation of protein autoubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination.	got7fsn_ti	downregulation of protein autoubiquitination|downregulation of protein auto-ubiquitinylation|inhibition of protein auto-ubiquitination|inhibition of protein self-ubiquitinylation|down regulation of protein autoubiquitination|downregulation of protein auto-ubiquitination|inhibition of protein auto-ubiquitinylation|down-regulation of protein auto-ubiquitinylation|down-regulation of protein autoubiquitinylation|down regulation of protein self-ubiquitination|negative regulation of protein self-ubiquitination|down-regulation of protein self-ubiquitination|down-regulation of protein auto-ubiquitination|inhibition of protein autoubiquitinylation|downregulation of protein self-ubiquitinylation|down regulation of protein self-ubiquitinylation|negative regulation of protein auto-ubiquitination|down regulation of protein auto-ubiquitinylation|negative regulation of protein autoubiquitinylation|downregulation of protein self-ubiquitination|negative regulation of protein self-ubiquitinylation|down-regulation of protein autoubiquitination|inhibition of protein autoubiquitination|down regulation of protein autoubiquitinylation|inhibition of protein self-ubiquitination|downregulation of protein autoubiquitinylation|down regulation of protein auto-ubiquitination|negative regulation of protein auto-ubiquitinylation|down-regulation of protein self-ubiquitinylation						bc	2016-10-04T10:53:25Z						biological_process											owl:Class	
GO:0097172	biolink:NamedThing	N-acetylmuramic acid metabolic process	The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.	got7fsn_ti	N-acetylmuramate metabolic process|N-acetylmuramate metabolism|N-acetylmuramic acid metabolism						pr	2011-10-07T12:45:24Z						biological_process											owl:Class	
GO:0043216	biolink:NamedThing	obsolete ATPase-coupled daunorubicin transmembrane transporter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out).	got7fsn_ti	daunorubicin-transporting ATPase activity|ATP-dependent daunorubicin transmembrane transporter activity|daunorubicin ABC transporter				This term was obsoleted because it represents a substrate-specific version of the general term GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity.	GO:0008559				True		RHEA:33147		molecular_function											owl:Class	
GO:0005566	biolink:NamedThing	obsolete ribosomal RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ribosomal RNA				This term was made obsolete because it represents a gene product.	GO:0005840|GO:0003735				True				molecular_function											owl:Class	
GO:1901839	biolink:NamedThing	regulation of RNA polymerase I regulatory region sequence-specific DNA binding	Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.	got7fsn_ti							sart	2013-01-23T10:24:33Z						biological_process											owl:Class	
GO:0052521	biolink:NamedThing	obsolete positive regulation by host of symbiont phagocytosis	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	stimulation by host of symbiont phagocytosis|up regulation by host of symbiont phagocytosis|activation by host of symbiont phagocytosis|up-regulation by host of symbiont phagocytosis|upregulation by host of symbiont phagocytosis	https://github.com/geneontology/go-ontology/issues/18562			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1905863	biolink:NamedThing	obsolete invadopodium organization	OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an invadopodium.	got7fsn_ti					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-01-25T22:54:14Z		True				biological_process											owl:Class	
GO:0097170	biolink:NamedThing	ADP-L-glycero-beta-D-manno-heptose metabolic process	The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.	got7fsn_ti	ADP-L-glycero-beta-D-manno-heptose metabolism						pr	2011-10-03T09:12:58Z						biological_process											owl:Class	
GO:1904486	biolink:NamedThing	response to 17alpha-ethynylestradiol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus.	got7fsn_ti							mr	2015-07-15T22:31:36Z						biological_process											owl:Class	
GO:1904562	biolink:NamedThing	phosphatidylinositol 5-phosphate metabolic process	The chemical reactions and pathways involving phosphatidylinositol 5-phosphate.	got7fsn_ti	phosphatidylinositol 5-phosphate metabolism						dph	2015-08-18T16:21:44Z						biological_process											owl:Class	
GO:0106041	biolink:NamedThing	positive regulation of GABA-A receptor activity	Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity.	got7fsn_ti							hjd	2017-07-27T18:51:30Z						biological_process											owl:Class	
GO:0006201	biolink:NamedThing	GMP catabolic process to IMP	The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate.	got7fsn_ti	GMP breakdown to IMP|GMP degradation to IMP													biological_process											owl:Class	
GO:1904149	biolink:NamedThing	regulation of microglial cell mediated cytotoxicity	Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity.	got7fsn_ti							nc	2015-04-15T08:05:29Z						biological_process											owl:Class	
GO:0070956	biolink:NamedThing	negative regulation of neutrophil mediated killing of bacterium	Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.	got7fsn_ti	down regulation of neutrophil mediated killing of bacterium|inhibition of neutrophil mediated killing of bacterium|down-regulation of neutrophil mediated killing of bacterium|downregulation of neutrophil mediated killing of bacterium						mah	2009-10-01T02:20:17Z						biological_process											owl:Class	
GO:0019330	biolink:NamedThing	aldoxime metabolic process	The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH.	got7fsn_ti	aldoxime metabolism											MetaCyc:P345-PWY		biological_process											owl:Class	
GO:2000712	biolink:NamedThing	regulation of maintenance of meiotic sister chromatid cohesion, arms	Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.	got7fsn_ti	regulation of maintenance of sister chromatin cohesion along arms at meiosis I|regulation of maintenance of meiotic sister chromatin cohesion along arms						mah	2011-06-01T12:45:35Z						biological_process											owl:Class	
GO:1900789	biolink:NamedThing	pseurotin A catabolic process	The chemical reactions and pathways resulting in the breakdown of pseurotin A.	got7fsn_ti	Pseurotin catabolic process|Pseurotin catabolism|Pseurotin degradation|pseurotin A catabolism|pseurotin A degradation|Pseurotin breakdown|pseurotin A breakdown						di	2012-06-04T09:37:41Z						biological_process											owl:Class	
GO:0071673	biolink:NamedThing	positive regulation of smooth muscle cell chemotaxis	Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.	got7fsn_ti	up-regulation of smooth muscle cell chemotaxis|stimulation of smooth muscle cell chemotaxis|up regulation of smooth muscle cell chemotaxis|upregulation of smooth muscle cell chemotaxis|activation of smooth muscle cell chemotaxis						mah	2010-02-16T01:48:14Z						biological_process											owl:Class	
GO:0061886	biolink:NamedThing	negative regulation of mini excitatory postsynaptic potential	Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.	got7fsn_ti							dph	2017-05-30T15:50:08Z						biological_process											owl:Class	
GO:0046046	biolink:NamedThing	TTP metabolic process	The chemical reactions and pathways involving TTP, ribosylthymine triphosphate.	got7fsn_ti	TTP metabolism													biological_process											owl:Class	
GO:0032800	biolink:NamedThing	obsolete receptor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti	receptor synthesis|receptor formation|receptor biosynthesis|receptor anabolism	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1903067	biolink:NamedThing	negative regulation of protein localization to cell tip	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip.	got7fsn_ti	down-regulation of protein localization to cell tip|down regulation of protein localization to cell tip|down regulation of protein localisation to cell tip|negative regulation of protein localisation to cell tip|down-regulation of protein localisation to cell tip|inhibition of protein localisation to cell tip|downregulation of protein localisation to cell tip|downregulation of protein localization to cell tip|inhibition of protein localization to cell tip						vw	2014-05-28T15:48:48Z						biological_process											owl:Class	
GO:1900182	biolink:NamedThing	positive regulation of protein localization to nucleus	Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.	got7fsn_ti	activation of protein localisation to nucleus|activation of protein localization in nucleus|up regulation of protein localization to nucleus|up-regulation of protein localization to nucleus|upregulation of protein localization in cell nucleus|activation of protein localization to nucleus|positive regulation of protein localization in nucleus|up-regulation of protein localization in nucleus|activation of protein localization in cell nucleus|up regulation of protein localisation to nucleus|up regulation of protein localization in nucleus|positive regulation of protein localisation to nucleus|positive regulation of protein localization in cell nucleus|up regulation of protein localization in cell nucleus|upregulation of protein localisation to nucleus|up-regulation of protein localization in cell nucleus|upregulation of protein localization to nucleus|up-regulation of protein localisation to nucleus|upregulation of protein localization in nucleus						bf	2012-03-12T01:23:52Z						biological_process											owl:Class	
GO:0036097	biolink:NamedThing	obsolete pre-miRNA 3'-end processing	OBSOLETE. Any process involved in forming the mature 3' end of a miRNA from a pre-miRNA.	got7fsn_ti	pre-miRNA 3'-end processing|microRNA 3'-end processing|miRNA 3'-end processing				This term was made obsolete because it is not real a process, and was created accidentally.		bf	2012-01-24T02:31:37Z		True				biological_process											owl:Class	
GO:0006404	biolink:NamedThing	RNA import into nucleus	The import of RNA from the cytoplasm to the nucleus.	got7fsn_ti	RNA import into cell nucleus|RNA transport from cytoplasm to nucleus|RNA-nucleus import													biological_process											owl:Class	
GO:1900447	biolink:NamedThing	regulation of cell morphogenesis involved in phenotypic switching	Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	got7fsn_ti	regulation of cell morphogenesis of phenotypic switching|regulation of cell morphogenesis of phenotypic dimorphism|positive regulation of cell shape and cell size of phenotypic switching|positive regulation of cell shape and cell size of phenotypic dimorphism|regulation of cell shape and cell size of phenotypic switching|negative regulation of cell shape and cell size of phenotypic dimorphism|negative regulation of cell shape and cell size of phenotypic switching|regulation of cell shape and cell size of phenotypic dimorphism						di	2012-04-27T02:43:32Z						biological_process											owl:Class	
GO:0006371	biolink:NamedThing	obsolete mRNA splicing	OBSOLETE. The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, so that mRNA consisting only of the joined exons is produced.	got7fsn_ti	mRNA splicing				This term was made obsolete because it represents several different processes.	GO:0000398|GO:0000372|GO:0000374|GO:0000373|GO:0000394				True				biological_process											owl:Class	
GO:0075098	biolink:NamedThing	obsolete negative regulation by host of symbiont signal transduction mediated by G-protein gamma subunit	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0005298	biolink:NamedThing	proline:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in).	got7fsn_ti	sodium/proline symporter activity											RHEA:28967|Reactome:R-HSA-444100		molecular_function											owl:Class	
GO:1900903	biolink:NamedThing	negative regulation of hexadecanal biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process.	got7fsn_ti	negative regulation of hexadecanal synthesis|downregulation of palmitaldehyde biosynthesis|negative regulation of hexadecanal anabolism|down-regulation of hexadecanal anabolism|inhibition of palmitaldehyde biosynthesis|negative regulation of palmitaldehyde biosynthesis|down-regulation of palmitaldehyde biosynthesis|down regulation of hexadecanal anabolism|down-regulation of hexadecanal synthesis|inhibition of hexadecanal anabolism|down regulation of hexadecanal biosynthetic process|inhibition of hexadecanal biosynthetic process|inhibition of hexadecanal biosynthesis|down regulation of hexadecanal synthesis|downregulation of hexadecanal biosynthetic process|inhibition of hexadecanal synthesis|downregulation of hexadecanal anabolism|down-regulation of palmitaldehyde biosynthetic process|downregulation of hexadecanal synthesis|down regulation of palmitaldehyde biosynthetic process|down-regulation of hexadecanal biosynthesis|down regulation of palmitaldehyde biosynthesis|downregulation of hexadecanal formation|down-regulation of hexadecanal formation|downregulation of hexadecanal biosynthesis|inhibition of hexadecanal formation|negative regulation of palmitaldehyde biosynthetic process|inhibition of palmitaldehyde biosynthetic process|negative regulation of hexadecanal formation|negative regulation of hexadecanal biosynthesis|down regulation of hexadecanal biosynthesis|downregulation of palmitaldehyde biosynthetic process|down-regulation of hexadecanal biosynthetic process|down regulation of hexadecanal formation						tt	2012-06-13T03:33:34Z						biological_process											owl:Class	
GO:0051710	biolink:NamedThing	regulation of cytolysis in other organism	Any process that modulates the frequency, rate or extent of the cytolysis by an organism of cells in another organism.	got7fsn_ti	regulation of cytolysis of cells of another, non-host, organism|regulation of cytolysis of cells of another organism										GO:0001902			biological_process											owl:Class	
GO:1900906	biolink:NamedThing	negative regulation of hexadecanal metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process.	got7fsn_ti	down-regulation of hexadecanal metabolism|down regulation of hexadecanal metabolic process|down-regulation of hexadecanal metabolic process|down regulation of hexadecanal metabolism|inhibition of hexadecanal metabolic process|downregulation of hexadecanal metabolism|inhibition of hexadecanal metabolism|downregulation of hexadecanal metabolic process|negative regulation of hexadecanal metabolism						tt	2012-06-13T03:35:54Z						biological_process											owl:Class	
GO:0015494	biolink:NamedThing	aromatic amino acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in).	got7fsn_ti	aromatic amino acid:hydrogen symporter activity													molecular_function											owl:Class	
GO:1903749	biolink:NamedThing	positive regulation of establishment of protein localization to mitochondrion	Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion.	got7fsn_ti	up-regulation of establishment of protein localisation to mitochondrion|upregulation of establishment of protein localization to mitochondrion|activation of establishment of protein localization in mitochondrion|activation of establishment of protein localization to mitochondrion|up regulation of establishment of protein localization in mitochondrion|up-regulation of establishment of protein localization in mitochondrion|upregulation of establishment of protein localisation to mitochondrion|up regulation of establishment of protein localisation to mitochondrion|upregulation of establishment of protein localization in mitochondrion|activation of establishment of protein localisation to mitochondrion|up regulation of establishment of protein localization to mitochondrion|positive regulation of establishment of protein localization in mitochondrion|up-regulation of establishment of protein localization to mitochondrion|positive regulation of establishment of protein localisation to mitochondrion						krc	2014-12-12T22:18:26Z						biological_process											owl:Class	
GO:0110088	biolink:NamedThing	hippocampal neuron apoptotic process	Any apoptotic process that occurs in a hippocampal neuron.	got7fsn_ti							kmv	2018-02-13T21:06:23Z						biological_process											owl:Class	
GO:0009659	biolink:NamedThing	leucoplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.	got7fsn_ti	leucoplast organisation|leucoplast organization and biogenesis													biological_process											owl:Class	
GO:0097160	biolink:NamedThing	polychlorinated biphenyl binding	Binding to a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings.	got7fsn_ti	polychlorobiphenyl binding|PCB binding						pr	2011-09-23T02:33:22Z						molecular_function											owl:Class	
GO:1905386	biolink:NamedThing	positive regulation of protein localization to presynapse	Any process that activates or increases the frequency, rate or extent of protein localization to presynapse.	got7fsn_ti	up-regulation of protein localization to presynapse|up regulation of recruitment of presynaptic proteins|up regulation of protein localisation in presynapse|positive regulation of protein localisation in presynapse|upregulation of protein localisation in presynapse|activation of protein localization to presynapse|activation of recruitment of presynaptic proteins|up-regulation of protein localisation in presynapse|positive regulation of protein localisation to presynapse|up-regulation of protein localisation to presynapse|upregulation of recruitment of presynaptic proteins|activation of protein localisation in presynapse|upregulation of protein localization to presynapse|upregulation of protein localization in presynapse|up-regulation of protein localization in presynapse|positive regulation of protein localization in presynapse|up regulation of protein localization to presynapse|up regulation of protein localization in presynapse|activation of protein localization in presynapse|upregulation of protein localisation to presynapse|activation of protein localisation to presynapse|positive regulation of recruitment of presynaptic proteins|up regulation of protein localisation to presynapse|up-regulation of recruitment of presynaptic proteins						dos	2016-08-18T14:56:21Z						biological_process											owl:Class	
GO:0015969	biolink:NamedThing	guanosine tetraphosphate metabolic process	The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.	got7fsn_ti	guanosine tetraphosphate (5'-ppGpp-3') metabolism|guanosine tetraphosphate (5'-ppGpp-3') metabolic process|guanosine tetraphosphate metabolism											MetaCyc:PPGPPMET-PWY		biological_process											owl:Class	
GO:0051041	biolink:NamedThing	positive regulation of calcium-independent cell-cell adhesion	Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion.	got7fsn_ti	up-regulation of calcium-independent cell-cell adhesion|stimulation of calcium-independent cell-cell adhesion|upregulation of calcium-independent cell-cell adhesion|activation of calcium-independent cell-cell adhesion|up regulation of calcium-independent cell-cell adhesion													biological_process											owl:Class	
GO:1903456	biolink:NamedThing	positive regulation of androst-4-ene-3,17-dione biosynthetic process	Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.	got7fsn_ti	positive regulation of androst-4-ene-3,17-dione synthesis|up-regulation of androst-4-ene-3,17-dione anabolism|activation of androst-4-ene-3,17-dione biosynthetic process|up regulation of androst-4-ene-3,17-dione biosynthetic process|up-regulation of androstenedione biosynthetic process|positive regulation of androst-4-ene-3,17-dione formation|activation of androst-4-ene-3,17-dione synthesis|up regulation of androstenedione biosynthetic process|activation of androst-4-ene-3,17-dione anabolism|upregulation of androst-4-ene-3,17-dione anabolism|up-regulation of androst-4-ene-3,17-dione biosynthetic process|activation of androst-4-ene-3,17-dione formation|up regulation of androst-4-ene-3,17-dione synthesis|up-regulation of androst-4-ene-3,17-dione biosynthesis|positive regulation of androstenedione biosynthetic process|upregulation of androst-4-ene-3,17-dione biosynthesis|up-regulation of androst-4-ene-3,17-dione formation|upregulation of androst-4-ene-3,17-dione synthesis|up regulation of androst-4-ene-3,17-dione anabolism|upregulation of androst-4-ene-3,17-dione biosynthetic process|up regulation of androst-4-ene-3,17-dione formation|up-regulation of androst-4-ene-3,17-dione synthesis|upregulation of androst-4-ene-3,17-dione formation|positive regulation of androst-4-ene-3,17-dione anabolism|positive regulation of androst-4-ene-3,17-dione biosynthesis|activation of androstenedione|activation of androst-4-ene-3,17-dione biosynthesis|up regulation of androst-4-ene-3,17-dione biosynthesis|upregulation of androstenedione biosynthetic process						mr	2014-09-22T14:37:07Z						biological_process											owl:Class	
GO:1902077	biolink:NamedThing	negative regulation of lateral motor column neuron migration	Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration.	got7fsn_ti	downregulation of lateral motor column neuron migration|down-regulation of lateral motor column neuron migration|down regulation of lateral motor column neuron migration|inhibition of lateral motor column neuron migration						pr	2013-04-23T14:42:23Z						biological_process											owl:Class	
GO:1903021	biolink:NamedThing	regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.	got7fsn_ti							tb	2014-05-14T23:44:35Z						biological_process											owl:Class	
GO:0051442	biolink:NamedThing	obsolete negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle.	got7fsn_ti	downregulation of ubiquitin ligase activity during meiotic cell cycle|meiotic anaphase promoting complex inhibition|meiotic APC inhibitor|inhibition of ubiquitin ligase activity during meiotic cell cycle|negative regulation of ubiquitin ligase activity during meiotic cell cycle|down-regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic SCF complex inhibitor|meiotic anaphase-promoting complex inhibition|meiotic anaphase-promoting complex inhibitor|meiotic APC inhibition|meiotic anaphase promoting complex inhibitor|down regulation of ubiquitin ligase activity during meiotic cell cycle|anaphase-promoting complex inhibition during meiotic cell cycle|anaphase promoting complex inhibition during meiotic cell cycle|meiotic ubiquitin ligase inhibitor|APC inhibition during meiotic cell cycle	https://github.com/geneontology/go-ontology/issues/15196			This term was obsoleted because it should be captured as a GO-CAM model.					True				biological_process											owl:Class	
GO:0052243	biolink:NamedThing	obsolete chemotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	chemotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1900880	biolink:NamedThing	18-methylnonadec-1-ene metabolic process	The chemical reactions and pathways involving 18-methylnonadec-1-ene.	got7fsn_ti	18-methylnonadec-1-ene metabolism						tt	2012-06-13T02:26:28Z						biological_process											owl:Class	
GO:2001266	biolink:NamedThing	Roundabout signaling pathway involved in axon guidance	Any Roundabout signaling pathway that is involved in axon guidance.	got7fsn_ti	Roundabout signalling pathway involved in axon pathfinding|ROBO signaling pathway involved in axon chemotaxis|ROBO/SLIT signaling pathway involved in axon chemotaxis|Roundabout signaling pathway involved in axon pathfinding|Roundabout signaling pathway involved in axon chemotaxis|Roundabout signaling pathway involved in axon growth cone guidance|ROBO signaling pathway involved in axon growth cone guidance|ROBO/SLIT signaling pathway involved in axon guidance|Roundabout signalling pathway involved in axon chemotaxis|ROBO/SLIT signaling pathway involved in axon growth cone guidance|Roundabout signalling pathway involved in axon growth cone guidance|ROBO signaling pathway involved in axon pathfinding|ROBO/SLIT signaling pathway involved in axon pathfinding|ROBO signaling pathway involved in axon guidance|Roundabout signalling pathway involved in axon guidance						bf	2011-12-12T03:40:20Z						biological_process											owl:Class	
GO:0042818	biolink:NamedThing	pyridoxamine metabolic process	The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti	pyridoxamine metabolism													biological_process											owl:Class	
GO:0086006	biolink:NamedThing	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti							tb	2011-11-10T08:34:49Z						molecular_function											owl:Class	
GO:0044034	biolink:NamedThing	obsolete multi-organism biosynthetic process	OBSOLETE. A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - which involves more than one organism.	got7fsn_ti	multi-organismal biosynthetic process|multi-organism biosynthesis|multi-organismal biosynthesis	https://github.com/geneontology/go-ontology/issues/18787			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1904036	biolink:NamedThing	negative regulation of epithelial cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process.	got7fsn_ti	downregulation of epithelial cell apoptosis|down-regulation of epithelial cell apoptotic process|negative regulation of epitheliocyte apoptotic process|down-regulation of epithelial cell apoptosis|down-regulation of epitheliocyte apoptotic process|down regulation of epithelial cell apoptosis|downregulation of epitheliocyte apoptosis|down regulation of epithelial cell apoptotic process|negative regulation of epitheliocyte apoptosis|negative regulation of epithelial cell apoptosis|downregulation of epitheliocyte apoptotic process|down-regulation of epitheliocyte apoptosis|down regulation of epitheliocyte apoptosis|downregulation of epithelial cell apoptotic process|down regulation of epitheliocyte apoptotic process|inhibition of epitheliocyte apoptosis|inhibition of epithelial cell apoptosis|inhibition of epithelial cell apoptotic process|inhibition of epitheliocyte apoptotic process						sl	2015-03-13T22:05:47Z						biological_process											owl:Class	
GO:1990908	biolink:NamedThing	obsolete Lys63-specific zinc metallopeptidase deubiquitinase activity	OBSOLETE. Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein by a mechanism where zinc acts as the nucleophile.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-12-03T14:25:04Z		True				molecular_function											owl:Class	
GO:0070323	biolink:NamedThing	obsolete positive regulation of translation in response to nitrogen starvation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen.	got7fsn_ti	up regulation of translation in response to nitrogen starvation|activation of translation in response to nitrogen starvation|upregulation of translation in response to nitrogen starvation|up-regulation of translation in response to nitrogen starvation|stimulation of translation in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/19092			This term was obsoleted because it was redundant with GO:1903833 ; positive regulation of cellular response to amino acid starvation.	GO:1903833				True				biological_process											owl:Class	
GO:0070135	biolink:NamedThing	beta-1,2-oligomannoside metabolic process	The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.	got7fsn_ti	beta-1,2-oligomannoside metabolism													biological_process											owl:Class	
GO:0015602	biolink:NamedThing	obsolete leucine/isoleucine/valine porter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).	got7fsn_ti	leucine/isoleucine/valine porter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015190|GO:0005304|GO:0015425|GO:0015188				True				molecular_function											owl:Class	
GO:0060093	biolink:NamedThing	negative regulation of synaptic transmission, glycinergic	Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.	got7fsn_ti	negative regulation of glycinergic synaptic transmission													biological_process											owl:Class	
GO:0032818	biolink:NamedThing	negative regulation of natural killer cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation.	got7fsn_ti	downregulation of natural killer cell proliferation|down regulation of natural killer cell proliferation|inhibition of natural killer cell proliferation|negative regulation of NK cell proliferation|down-regulation of natural killer cell proliferation													biological_process											owl:Class	
GO:1900508	biolink:NamedThing	positive regulation of iron-sulfur-molybdenum cofactor assembly	Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.	got7fsn_ti	upregulation of iron molybdenum cofactor biosynthesis|up-regulation of FeMoco biosynthetic process|up regulation of iron-sulfur-molybdenum cofactor assembly|activation of iron molybdenum cofactor assembly|activation of FeMoco assembly|up regulation of FeMoco assembly|positive regulation of FeMoco biosynthetic process|activation of iron molybdenum cofactor biosynthesis|up regulation of FeMoco biosynthetic process|up-regulation of iron molybdenum cofactor biosynthetic process|upregulation of iron molybdenum cofactor biosynthetic process|positive regulation of iron molybdenum cofactor biosynthesis|up-regulation of iron-sulfur-molybdenum cofactor assembly|positive regulation of iron molybdenum cofactor biosynthetic process|up-regulation of iron molybdenum cofactor assembly|upregulation of iron-sulfur-molybdenum cofactor assembly|upregulation of iron molybdenum cofactor assembly|up regulation of iron molybdenum cofactor biosynthetic process|positive regulation of iron molybdenum cofactor assembly|up-regulation of iron molybdenum cofactor biosynthesis|positive regulation of FeMoco assembly|activation of FeMoco biosynthetic process|up regulation of iron molybdenum cofactor biosynthesis|upregulation of FeMoco biosynthetic process|up regulation of iron molybdenum cofactor assembly|upregulation of FeMoco assembly|activation of iron-sulfur-molybdenum cofactor assembly|up-regulation of FeMoco assembly|activation of iron molybdenum cofactor biosynthetic process						tt	2012-05-02T04:02:37Z						biological_process											owl:Class	
GO:1900774	biolink:NamedThing	fumiquinazoline catabolic process	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline.	got7fsn_ti	fumiquinazoline degradation|fumiquinazoline catabolism|fumiquinazolines breakdown|fumiquinazolines degradation|fumiquinazolines catabolism|fumiquinazoline breakdown|fumiquinazolines catabolic process						di	2012-06-04T09:29:46Z						biological_process											owl:Class	
GO:0090420	biolink:NamedThing	obsolete naphthalene-containing compound metabolic process	OBSOLETE. The chemical reactions and pathways involving naphthalene-containing compounds.	got7fsn_ti					This term was obsoleted because it is a unnecessary grouping class.		tb	2011-12-12T11:32:34Z		True				biological_process											owl:Class	
GO:1900964	biolink:NamedThing	positive regulation of methanophenazine biosynthetic process	Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process.	got7fsn_ti	up regulation of methanophenazine anabolism|positive regulation of methanophenazine formation|upregulation of methanophenazine biosynthesis|upregulation of methanophenazine synthesis|activation of methanophenazine biosynthesis|activation of methanophenazine anabolism|up-regulation of methanophenazine biosynthetic process|up regulation of methanophenazine biosynthesis|activation of methanophenazine synthesis|activation of methanophenazine biosynthetic process|upregulation of methanophenazine biosynthetic process|up regulation of methanophenazine formation|activation of methanophenazine formation|up-regulation of methanophenazine synthesis|up-regulation of methanophenazine biosynthesis|up regulation of methanophenazine synthesis|up-regulation of methanophenazine formation|up-regulation of methanophenazine anabolism|up regulation of methanophenazine biosynthetic process|upregulation of methanophenazine anabolism|positive regulation of methanophenazine biosynthesis|upregulation of methanophenazine formation|positive regulation of methanophenazine anabolism|positive regulation of methanophenazine synthesis						tt	2012-06-14T03:53:46Z						biological_process											owl:Class	
GO:0106246	biolink:NamedThing	regulation of poly(A)-specific ribonuclease activity	Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.	got7fsn_ti							hjd	2020-02-03T18:56:03Z						biological_process											owl:Class	
GO:1905057	biolink:NamedThing	voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels	Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	got7fsn_ti	dihydropyridine-sensitive calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-dependent calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage-gated calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-sensitive calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels|voltage-gated calcium ion channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration						dos	2016-03-18T12:31:48Z						molecular_function											owl:Class	
GO:0019025	biolink:NamedThing	obsolete positive sense viral genome	OBSOLETE. A single stranded RNA genome with the same nucleotide polarity as mRNA.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:1905227	biolink:NamedThing	negative regulation of adhesion of symbiont to host epithelial cell	Any process that stops, prevents or reduces the frequency, rate or extent of adhesion of symbiont to host epithelial cell.	got7fsn_ti	downregulation of adhesion of symbiont to host epithelial cell|inhibition of adhesion of symbiont to host epithelial cell|down regulation of adhesion of symbiont to host epithelial cell|down-regulation of adhesion of symbiont to host epithelial cell						pga	2016-06-07T13:15:16Z						biological_process											owl:Class	
GO:0100021	biolink:NamedThing	obsolete regulation of iron ion transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates iron ion transport.	got7fsn_ti	regulation of iron ion import by transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True	GO:0100022			biological_process											owl:Class	
GO:0033389	biolink:NamedThing	putrescine biosynthetic process from arginine, using agmatinase	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.	got7fsn_ti	putrescine anabolism from arginine, using agmatinase|putrescine formation from arginine, using agmatinase|putrescine biosynthesis from arginine, using agmatinase|putrescine synthesis from arginine, using agmatinase													biological_process											owl:Class	
GO:2000279	biolink:NamedThing	negative regulation of DNA biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.	got7fsn_ti	negative regulation of DNA biosynthesis|negative regulation of DNA synthesis|negative regulation of DNA formation|negative regulation of DNA anabolism						yaf	2010-12-08T04:48:20Z						biological_process											owl:Class	
GO:0014872	biolink:NamedThing	myoblast division	The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:2000316	biolink:NamedThing	regulation of T-helper 17 type immune response	Any process that modulates the frequency, rate or extent of T-helper 17 type immune response.	got7fsn_ti	regulation of Th17 immune response						mah	2011-01-18T01:32:26Z						biological_process											owl:Class	
GO:1900669	biolink:NamedThing	positive regulation of endocrocin biosynthetic process	Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process.	got7fsn_ti	up regulation of endocrocin synthesis|up regulation of endocrocin anabolism|activation of endocrocin formation|up regulation of endocrocin biosynthetic process|activation of endocrocin biosynthesis|activation of endocrocin anabolism|positive regulation of endocrocin formation|positive regulation of endocrocin synthesis|activation of endocrocin biosynthetic process|activation of endocrocin synthesis|upregulation of endocrocin synthesis|positive regulation of endocrocin biosynthesis|upregulation of endocrocin anabolism|up regulation of endocrocin biosynthesis|up-regulation of endocrocin anabolism|up-regulation of endocrocin synthesis|up regulation of endocrocin formation|upregulation of endocrocin biosynthetic process|up-regulation of endocrocin biosynthetic process|upregulation of endocrocin biosynthesis|up-regulation of endocrocin formation|upregulation of endocrocin formation|up-regulation of endocrocin biosynthesis|positive regulation of endocrocin anabolism						di	2012-05-22T04:16:35Z						biological_process											owl:Class	
GO:0085040	biolink:NamedThing	obsolete extra-invasive hyphal space	OBSOLETE. The space between the symbiont plasma membrane and the extra-invasive hyphal membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19013			This term was obsoleted because the cellular component represented is not different from 'host cytoplasm'.		jl	2010-07-27T04:21:26Z		True				cellular_component											owl:Class	
GO:1902895	biolink:NamedThing	positive regulation of pri-miRNA transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.	got7fsn_ti	up regulation of pri-miRNA transcription from RNA polymerase II promoter|upregulation of pri-miRNA transcription from RNA polymerase II promoter|positive regulation of pri-miRNA transcription from RNA polymerase II promoter|activation of pri-miRNA transcription from RNA polymerase II promoter|up-regulation of pri-miRNA transcription from RNA polymerase II promoter						dph	2014-04-08T13:22:20Z						biological_process											owl:Class	
GO:1901525	biolink:NamedThing	negative regulation of mitophagy	Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy.	got7fsn_ti	negative regulation of macromitophagy|down-regulation of macromitophagy|down regulation of macromitophagy|downregulation of macromitophagy|inhibition of macromitophagy						krc	2012-10-22T16:56:49Z						biological_process											owl:Class	
GO:1903280	biolink:NamedThing	negative regulation of calcium:sodium antiporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity.	got7fsn_ti	downregulation of sodium/calcium exchanger|inhibition of sodium/calcium exchanger|negative regulation of sodium:calcium exchange|down regulation of calcium:sodium antiporter activity|inhibition of calcium:sodium antiporter activity|down regulation of sodium/calcium exchanger|inhibition of sodium:calcium exchange|inhibition of mitochondrial sodium/calcium ion exchange|downregulation of sodium:calcium exchange|negative regulation of sodium/calcium exchanger|down-regulation of sodium:calcium exchange|downregulation of mitochondrial sodium/calcium ion exchange|down regulation of mitochondrial sodium/calcium ion exchange|down-regulation of sodium/calcium exchanger|negative regulation of mitochondrial sodium/calcium ion exchange|down-regulation of mitochondrial sodium/calcium ion exchange|downregulation of calcium:sodium antiporter activity|down-regulation of calcium:sodium antiporter activity|down regulation of sodium:calcium exchange						rl	2014-08-11T12:53:38Z						biological_process											owl:Class	
GO:0010131	biolink:NamedThing	obsolete sucrose catabolic process, using invertase or sucrose synthase	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose by the enzymatic action of either invertase or sucrose synthase.	got7fsn_ti	sucrose breakdown, using invertase or sucrose synthase|sucrose degradation, using invertase or sucrose synthase|sucrose catabolic process, using invertase or sucrose synthase|sucrose catabolism, using invertase or sucrose synthase				This term was made obsolete because it describes two different routes of sucrose catabolism, both of which are represented by molecular functions.	GO:0016157|GO:0004564|GO:0005987				True		MetaCyc:PWY-621|MetaCyc:PWY-3801		biological_process											owl:Class	
GO:0019542	biolink:NamedThing	propionate biosynthetic process	The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid.	got7fsn_ti	propionate biosynthesis|propionate synthesis|propionate formation|propionate anabolism													biological_process											owl:Class	
GO:0019837	biolink:NamedThing	obsolete herbicide susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	herbicide susceptibility/resistance			GO:0009635	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0018957	biolink:NamedThing	phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite.	got7fsn_ti	phenanthrene degradation via trans-9(S),10(S)-dihydrodiolphenanthrene|phenanthrene breakdown via trans-9(S),10(S)-dihydrodiolphenanthrene											UM-BBD_pathwayID:pha2		biological_process											owl:Class	
GO:0030885	biolink:NamedThing	regulation of myeloid dendritic cell activation	Any process that modulates the frequency or rate of myeloid dendritic cell activation.	got7fsn_ti														biological_process											owl:Class	
GO:0071392	biolink:NamedThing	cellular response to estradiol stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	got7fsn_ti	cellular response to E2 stimulus						mah	2009-12-11T04:10:31Z						biological_process											owl:Class	
GO:1901955	biolink:NamedThing	negative regulation of retrograde dense core granule transport	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.	got7fsn_ti	downregulation of retrograde dense core granule transport|down regulation of retrograde dense core granule transport|inhibition of retrograde dense core granule transport|down-regulation of retrograde dense core granule transport						pr	2013-02-19T13:36:47Z						biological_process											owl:Class	
GO:1903837	biolink:NamedThing	regulation of mRNA 3'-UTR binding	Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding.	got7fsn_ti	regulation of mRNA 3' UTR binding						als	2015-01-22T11:53:59Z						biological_process											owl:Class	
GO:1905146	biolink:NamedThing	lysosomal protein catabolic process	Any cellular protein catabolic process that takes place in a lysosome.	got7fsn_ti	proteolysis within lysosome|lysosomal protein catabolism|cellular protein catabolism in lysosome|cellular protein catabolic process in lysosome|cellular protein breakdown in lysosome|lysosomal proteolysis|cellular protein degradation in lysosome|lysosomal protein degradation				Also consider annotating to the term 'autophagy ; GO:0006914' or one of its descendants.		bf	2016-04-14T12:50:34Z						biological_process											owl:Class	
GO:0031551	biolink:NamedThing	regulation of brain-derived neurotrophic factor-activated receptor activity	Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.	got7fsn_ti	regulation of brain-derived neurotrophic factor receptor activity|regulation of BDNF receptor activity													biological_process											owl:Class	
GO:0009458	biolink:NamedThing	obsolete cytochrome	OBSOLETE. A hemeprotein whose characteristic mode of action involves transfer of reducing equivalents associated with a reversible change in oxidation state of the prosthetic group. This redox change involves a single electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom.	got7fsn_ti	cytochrome				This term was made obsolete because it represents a gene product.	GO:0004129				True				molecular_function											owl:Class	
GO:0015472	biolink:NamedThing	obsolete fimbrium-specific chaperone activity	OBSOLETE. Assists in the correct assembly of fimbria, extracellular organelles that are used to attach a bacterial cell to a surface, but is not a component of the fimbrium when performing its normal biological function.	got7fsn_ti	fimbrium-specific chaperone activity				This term was made obsolete because it refers to a class of proteins and a biological process rather than a molecular function.	GO:0044183|GO:0051082|GO:0009297|GO:0030674				True				molecular_function											owl:Class	
GO:0072308	biolink:NamedThing	negative regulation of metanephric nephron tubule epithelial cell differentiation	Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.	got7fsn_ti							mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:1902060	biolink:NamedThing	positive regulation of sporocarp development involved in sexual reproduction	Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction.	got7fsn_ti	upregulation of fruiting body formation involved in sexual reproduction|upregulation of perfect stage fruiting body development|up regulation of perfect stage fruiting body development|up-regulation of ascus development|up-regulation of fruiting body formation involved in sexual reproduction|up-regulation of perfect stage fruiting body development|up-regulation of sporocarp development involved in sexual reproduction|upregulation of fruiting body development involved in sexual reproduction|activation of ascus development|positive regulation of fruiting body formation involved in sexual reproduction|activation of fruiting body formation involved in sexual reproduction|upregulation of sporocarp development involved in sexual reproduction|up regulation of sporocarp development involved in sexual reproduction|activation of sporocarp development involved in sexual reproduction|up regulation of ascus development|activation of fruiting body development involved in sexual reproduction|up-regulation of fruiting body development involved in sexual reproduction|positive regulation of fruiting body development involved in sexual reproduction|up regulation of fruiting body formation involved in sexual reproduction|upregulation of ascus development|positive regulation of perfect stage fruiting body development|up regulation of fruiting body development involved in sexual reproduction|activation of perfect stage fruiting body development|positive regulation of ascus development						di	2013-04-16T04:08:47Z						biological_process											owl:Class	
GO:1902151	biolink:NamedThing	regulation of response to DNA integrity checkpoint signaling	Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling.	got7fsn_ti	regulation of response to signal involved in DNA integrity checkpoint|regulation of DNA integrity checkpoint effector process						jl	2013-05-21T15:44:26Z						biological_process											owl:Class	
GO:0032570	biolink:NamedThing	response to progesterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.	got7fsn_ti	response to progesterone stimulus													biological_process											owl:Class	
GO:0072733	biolink:NamedThing	response to staurosporine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.	got7fsn_ti							mah	2012-07-17T10:32:28Z						biological_process											owl:Class	
GO:0060469	biolink:NamedThing	positive regulation of transcription involved in egg activation	Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation.	got7fsn_ti	activation of the egg genome|activation of the maternal genome													biological_process											owl:Class	
GO:2000090	biolink:NamedThing	regulation of mesonephric glomerular mesangial cell proliferation	Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.	got7fsn_ti							dph	2010-09-03T06:10:28Z						biological_process											owl:Class	
GO:0030444	biolink:NamedThing	obsolete microtubule depolymerization during nuclear congression	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	microtubule depolymerization during nuclear congression			GO:0007019	This term was made obsolete because the entire branch of the ontology was changed.					True				biological_process											owl:Class	
GO:0097050	biolink:NamedThing	type B pancreatic cell apoptotic process	Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.	got7fsn_ti	pancreatic beta cell apoptosis|pancreatic B cell apoptosis|type B pancreatic cell apoptosis						pr	2011-05-04T02:24:38Z						biological_process											owl:Class	
GO:1903253	biolink:NamedThing	hercynylcysteine sulfoxide biosynthetic process	The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide.	got7fsn_ti	hercynylcysteine sulfoxide formation|hercynylcysteine sulfoxide biosynthesis|hercynylcysteine sulfoxide synthesis|hercynylcysteine sulfoxide anabolism						mah	2014-08-06T09:14:00Z						biological_process											owl:Class	
GO:0045021	biolink:NamedThing	obsolete error-free DNA repair	OBSOLETE. DNA repair pathways that do not increase the mutation rate above spontaneous background levels, e.g. excision and recombination pathways.	got7fsn_ti	error-free DNA repair				This term was made obsolete because 'error-free' does not correspond to a repair mechanism, and the term has been superseded by more specific terms.	GO:0042275|GO:0070987				True				biological_process											owl:Class	
GO:0020028	biolink:NamedThing	endocytic hemoglobin import into cell	The directed movement of hemoglobin into a cell by receptor-mediated endocytosis.	got7fsn_ti	hemoglobin uptake|haemoglobin uptake|endocytic hemoglobin import													biological_process											owl:Class	
GO:0004865	biolink:NamedThing	protein serine/threonine phosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0050773	biolink:NamedThing	regulation of dendrite development	Any process that modulates the frequency, rate or extent of dendrite development.	got7fsn_ti														biological_process											owl:Class	
GO:1900651	biolink:NamedThing	positive regulation of dehydroaustinol biosynthetic process	Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process.	got7fsn_ti	activation of dehydroaustinol formation|positive regulation of dehydroaustinol synthesis|upregulation of dehydroaustinol biosynthesis|positive regulation of dehydroaustinol anabolism|activation of dehydroaustinol anabolism|positive regulation of dehydroaustinol biosynthesis|upregulation of dehydroaustinol biosynthetic process|up regulation of dehydroaustinol biosynthetic process|activation of dehydroaustinol synthesis|activation of dehydroaustinol biosynthesis|upregulation of dehydroaustinol synthesis|up-regulation of dehydroaustinol formation|up-regulation of dehydroaustinol anabolism|positive regulation of dehydroaustinol formation|up-regulation of dehydroaustinol synthesis|up-regulation of dehydroaustinol biosynthesis|upregulation of dehydroaustinol formation|up regulation of dehydroaustinol formation|up-regulation of dehydroaustinol biosynthetic process|upregulation of dehydroaustinol anabolism|activation of dehydroaustinol biosynthetic process|up regulation of dehydroaustinol synthesis|up regulation of dehydroaustinol anabolism|up regulation of dehydroaustinol biosynthesis						di	2012-05-22T04:06:30Z						biological_process											owl:Class	
GO:1990365	biolink:NamedThing	obsolete response to phenol	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phenols.	got7fsn_ti	response to phenol				This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:20:00Z		True				biological_process											owl:Class	
GO:1904954	biolink:NamedThing	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	Any canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway through beta-catenin involved in midbrain DA neurogenesis|Wnt receptor signaling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway via beta-catenin involved in midbrain DA neurogenesis|canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway through beta-catenin involved in mDA neuron differentiation|Wnt receptor signaling pathway through beta-catenin involved in midbrain DA neurogenesis|Wnt receptor signalling pathway through beta-catenin involved in mDA neuron differentiation|canonical Wnt-mediated midbrain DA neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in DA neurogenesis from midbrain floor plate|canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis|canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|canonical Wnt signaling pathway involved in midbrain DA neurogenesis|canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron production|canonical Wnt signaling pathway involved in mDA neuron differentiation|canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis|canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron production|canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|frizzled-1 receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron differentiation|frizzled-1 receptor signaling pathway involved in midbrain DA neurogenesis|canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron production|canonical Wnt-activated signaling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in mDA neuron differentiation|Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron production|frizzled-1 receptor signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate|canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate						bf	2016-02-09T11:04:46Z						biological_process											owl:Class	
GO:1903226	biolink:NamedThing	positive regulation of endodermal cell differentiation	Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.	got7fsn_ti	positive regulation of endoderm cell differentiation|up regulation of endodermal cell differentiation|up-regulation of endoderm cell differentiation|upregulation of endoderm cell differentiation|up regulation of endoderm cell differentiation|activation of endoderm cell differentiation|upregulation of endodermal cell differentiation|up-regulation of endodermal cell differentiation|activation of endodermal cell differentiation						als	2014-07-29T13:22:47Z						biological_process											owl:Class	
GO:2001245	biolink:NamedThing	regulation of phosphatidylcholine biosynthetic process	Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process.	got7fsn_ti	regulation of phosphatidylcholine anabolism|regulation of phosphatidylcholine synthesis|regulation of phosphatidylcholine formation|regulation of phosphatidylcholine biosynthesis						tb	2011-11-28T09:47:32Z						biological_process											owl:Class	
GO:0032460	biolink:NamedThing	negative regulation of protein oligomerization	Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.	got7fsn_ti	down-regulation of protein oligomerization|down regulation of protein oligomerization|inhibition of protein oligomerization|downregulation of protein oligomerization													biological_process											owl:Class	
GO:1902629	biolink:NamedThing	regulation of mRNA stability involved in cellular response to UV	Any regulation of mRNA stability that is involved in cellular response to UV.	got7fsn_ti	regulation of mRNA stability involved in cellular response to ultraviolet radiation stimulus|regulation of mRNA stability involved in cellular response to ultraviolet light stimulus|regulation of mRNA stability involved in cellular response to UV light stimulus|regulation of mRNA stability involved in cellular response to UV radiation stimulus						mah	2014-01-17T12:23:38Z						biological_process											owl:Class	
GO:1902550	biolink:NamedThing	lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis	Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis.	got7fsn_ti	lymphoid lineage restricted progenitor cell migration into thymus involved in thymic epithelium morphogenesis|lymphoid lineage restricted progenitor cell migration into thymus involved in thymus epithelium morphogenesis|lymphoid lineage cell migration into thymus involved in thymic epithelium morphogenesis						pr	2013-12-04T21:13:33Z						biological_process											owl:Class	
GO:1905334	biolink:NamedThing	Swi5-Sfr1 complex binding	Binding to a Swi5-Sfr1 complex.	got7fsn_ti	Sae3-Mei5 complex binding						al	2016-07-25T16:18:58Z						molecular_function											owl:Class	
GO:1901626	biolink:NamedThing	regulation of postsynaptic membrane organization	Any process that modulates the frequency, rate or extent of postsynaptic membrane organization.	got7fsn_ti	regulation of post-synaptic membrane organization|regulation of postsynaptic membrane organisation						ans	2012-11-15T11:40:15Z						biological_process											owl:Class	
CHEBI:17252	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905105	biolink:NamedThing	obsolete cellular response to ouabain	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-04-04T19:08:16Z		True				biological_process											owl:Class	
GO:0070666	biolink:NamedThing	regulation of mast cell proliferation	Any process that modulates the frequency, rate or extent of mast cell proliferation.	got7fsn_ti							mah	2009-05-28T05:40:43Z						biological_process											owl:Class	
GO:0046044	biolink:NamedThing	TMP metabolic process	The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.	got7fsn_ti	TMP metabolism													biological_process											owl:Class	
GO:0031622	biolink:NamedThing	positive regulation of fever generation	Any process that activates or increases the frequency, rate, or extent of fever generation.	got7fsn_ti	up regulation of fever|positive regulation of pyrexia|activation of fever|stimulation of fever|up-regulation of fever|upregulation of fever													biological_process											owl:Class	
GO:0019016	biolink:NamedThing	obsolete non-segmented viral genome	OBSOLETE. A viral genome that consists of one continuous nucleic acid molecule.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:1901262	biolink:NamedThing	negative regulation of sorocarp spore cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.	got7fsn_ti	downregulation of sorocarp spore cell differentiation|inhibition of sorocarp spore cell differentiation|down regulation of sorocarp spore cell differentiation|down-regulation of sorocarp spore cell differentiation						jl	2012-08-15T09:44:50Z						biological_process											owl:Class	
GO:1903507	biolink:NamedThing	negative regulation of nucleic acid-templated transcription	Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.	got7fsn_ti	downregulation of nucleic acid-templated transcription|down regulation of nucleic acid-templated transcription|inhibition of nucleic acid-templated transcription|down-regulation of nucleic acid-templated transcription						pr	2014-10-01T14:44:56Z						biological_process											owl:Class	
GO:0015563	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015854	biolink:NamedThing	guanine transport	The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0005318	biolink:NamedThing	obsolete phosphate:hydrogen symporter	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	phosphate:hydrogen symporter|phosphate:proton symporter activity					GO:0015317				True				molecular_function											owl:Class	
GO:2000605	biolink:NamedThing	positive regulation of secondary growth	Any process that activates or increases the frequency, rate or extent of secondary growth.	got7fsn_ti							tb	2011-04-15T10:30:49Z						biological_process											owl:Class	
GO:0048405	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905614	biolink:NamedThing	negative regulation of developmental vegetative growth	Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth.	got7fsn_ti	downregulation of developmental vegetative growth|down-regulation of developmental vegetative growth|down regulation of developmental vegetative growth|inhibition of developmental vegetative growth						pga	2016-10-28T11:45:20Z						biological_process											owl:Class	
GO:0090319	biolink:NamedThing	positive regulation of chylomicron remodeling	Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.	got7fsn_ti							tb	2010-04-30T10:09:08Z						biological_process											owl:Class	
GO:0030064	biolink:NamedThing	obsolete cell wall inner membrane	OBSOLETE. The peptidoglycan layer of the cell wall of Gram-negative bacteria.	got7fsn_ti	cell wall inner membrane				This term was made obsolete because it was defined inaccurately.	GO:0009276				True				cellular_component											owl:Class	
GO:1905750	biolink:NamedThing	negative regulation of endosome to plasma membrane protein transport	Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport.	got7fsn_ti	downregulation of endosome to plasma membrane protein transport|inhibition of endosome to plasma membrane protein transport|down-regulation of endosome to plasma membrane protein transport|down regulation of endosome to plasma membrane protein transport						pga	2016-12-09T13:46:21Z						biological_process											owl:Class	
GO:0002038	biolink:NamedThing	positive regulation of L-glutamate import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell.	got7fsn_ti	upregulation of L-glutamate uptake|up-regulation of L-glutamate import|up regulation of L-glutamate import|stimulation of L-glutamate transport|up-regulation of L-glutamate uptake|activation of L-glutamate import|up regulation of L-glutamate uptake|activation of L-glutamate transport|upregulation of L-glutamate import|activation of L-glutamate uptake|positive regulation of L-glutamate uptake|positive regulation of L-glutamate transport|upregulation of L-glutamate transport|up-regulation of L-glutamate transport|positive regulation of L-glutamate import|up regulation of L-glutamate transport						al	2012-06-13T07:34:38Z			GO:1900922			biological_process											owl:Class	
GO:2000435	biolink:NamedThing	negative regulation of protein neddylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation.	got7fsn_ti	negative regulation of RUB1-protein conjugation						vw	2011-03-03T02:05:56Z						biological_process											owl:Class	
GO:2001085	biolink:NamedThing	arabinogalactan binding	Binding to arabinogalactan.	got7fsn_ti							jl	2011-09-15T01:35:51Z						molecular_function											owl:Class	
GO:0015743	biolink:NamedThing	malate transport	The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	mitochondrial alpha-ketoglutarate/malate transport													biological_process											owl:Class	
GO:0052524	biolink:NamedThing	obsolete positive regulation by organism of symbiont salicylic acid-mediated defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of symbiont SA-mediated defense response|positive regulation by organism of symbiont salicylic acid-mediated defense response|induction by organism of symbiont salicylic acid-mediated defense response|positive regulation by organism of symbiont SA-mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0072391	biolink:NamedThing	phenol biosynthetic process	The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.	got7fsn_ti							mah	2010-12-06T04:08:04Z						biological_process											owl:Class	
GO:0051411	biolink:NamedThing	obsolete ALP binding	OBSOLETE. Interacting selectively and non-covalently wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band.	got7fsn_ti	actinin-associated LIM protein binding|ALP binding			GO:0008092	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:0075021	biolink:NamedThing	obsolete cAMP-mediated activation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cAMP mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	cyclic AMP mediated activation of appressorium formation				This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1904934	biolink:NamedThing	negative regulation of cell proliferation in midbrain	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain.	got7fsn_ti	down-regulation of cell proliferation in midbrain|downregulation of cell proliferation in midbrain|inhibition of cell proliferation in mesencephalon|down-regulation of mesencepahalic cell proliferation|negative regulation of cell proliferation in mesencephalon|inhibition of cell proliferation in midbrain|inhibition of mesencepahalic cell proliferation|down regulation of cell proliferation in midbrain|down-regulation of cell proliferation in mesencephalon|down regulation of mesencepahalic cell proliferation|downregulation of mesencepahalic cell proliferation|negative regulation of mesencepahalic cell proliferation|downregulation of cell proliferation in mesencephalon|down regulation of cell proliferation in mesencephalon						bf	2016-02-01T13:16:19Z						biological_process											owl:Class	
GO:0008041	biolink:NamedThing	obsolete storage protein of fat body (sensu Insecta)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	storage protein of fat body (sensu Insecta)			GO:0045735	This term was made obsolete because it describes a cellular location rather than a function.					True				molecular_function											owl:Class	
GO:0032964	biolink:NamedThing	collagen biosynthetic process	The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).	got7fsn_ti	collagen formation|collagen biosynthesis|collagen anabolism|collagen synthesis													biological_process											owl:Class	
GO:0039551	biolink:NamedThing	obsolete suppression by virus of host IRF3 activity by positive regulation of IRF3 catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3) by promoting the ubiquitin-dependent degradation of IRF3, mediated by the proteasome.	got7fsn_ti	promotion by virus of proteosome-dependent IRF3 degradation				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-20T11:35:33Z		True				biological_process											owl:Class	
GO:1902184	biolink:NamedThing	negative regulation of shoot apical meristem development	Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development.	got7fsn_ti	inhibition of primary shoot meristem development|down-regulation of primary shoot meristem development|negative regulation of primary shoot meristem development|negative regulation of promeristem development|down-regulation of SAM development|downregulation of SAM development|inhibition of promeristem development|down-regulation of shoot apical meristem development|down regulation of primary shoot meristem development|downregulation of promeristem development|down-regulation of promeristem development|inhibition of SAM development|downregulation of primary shoot meristem development|down regulation of SAM development|down regulation of shoot apical meristem development|down regulation of promeristem development|negative regulation of SAM development|downregulation of shoot apical meristem development|inhibition of shoot apical meristem development						tb	2013-05-31T16:34:00Z						biological_process											owl:Class	
GO:1901666	biolink:NamedThing	positive regulation of NAD+ ADP-ribosyltransferase activity	Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.	got7fsn_ti	activation of poly(ADP-ribose)polymerase activity|positive regulation of NAD ADP-ribosyltransferase activity|activation of NAD ADP-ribosyltransferase activity|up-regulation of ADP-ribosyltransferase (polymerizing) activity|up-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up-regulation of poly(ADP-ribose)polymerase activity|up regulation of poly(adenosine diphosphate ribose) polymerase activity|activation of poly(ADP-ribose) synthetase activity|up regulation of poly(ADP-ribose) synthase activity|upregulation of poly(ADP-ribose) synthetase activity|upregulation of poly(ADP-ribose) synthase activity|activation of ADP-ribosyltransferase (polymerizing) activity|activation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up regulation of poly(ADP-ribose)polymerase activity|up regulation of ADP-ribosyltransferase (polymerizing) activity|up regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up-regulation of poly(adenosine diphosphate ribose) polymerase activity|activation of poly(ADP-ribose) synthase activity|up-regulation of NAD+ ADP-ribosyltransferase activity|upregulation of NAD ADP-ribosyltransferase activity|positive regulation of poly(ADP-ribose) synthase activity|upregulation of poly(adenosine diphosphate ribose) polymerase activity|positive regulation of ADP-ribosyltransferase (polymerizing) activity|activation of NAD+ ADP-ribosyltransferase activity|upregulation of poly(ADP-ribose)polymerase activity|positive regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up regulation of poly(ADP-ribose) synthetase activity|positive regulation of poly(ADP-ribose) synthetase activity|up regulation of NAD+ ADP-ribosyltransferase activity|up-regulation of NAD ADP-ribosyltransferase activity|up regulation of NAD ADP-ribosyltransferase activity|upregulation of ADP-ribosyltransferase (polymerizing) activity|upregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|positive regulation of poly(adenosine diphosphate ribose) polymerase activity|up-regulation of poly(ADP-ribose) synthase activity|positive regulation of poly(ADP-ribose)polymerase activity|activation of poly(adenosine diphosphate ribose) polymerase activity|upregulation of NAD+ ADP-ribosyltransferase activity|up-regulation of poly(ADP-ribose) synthetase activity						vk	2012-11-20T18:50:20Z						biological_process											owl:Class	
GO:1900026	biolink:NamedThing	positive regulation of substrate adhesion-dependent cell spreading	Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.	got7fsn_ti	positive regulation of cell spreading during cell substrate adhesion|up regulation of cell spreading during cell substrate adhesion|up regulation of substrate adhesion dependent cell spreading|up regulation of substrate adhesion-dependent cell spreading|positive regulation of substrate adhesion dependent cell spreading						yaf	2012-01-12T05:00:46Z						biological_process											owl:Class	
GO:0003731	biolink:NamedThing	obsolete mRNA cap binding	OBSOLETE. Interacting selectively with the 7-methylguanosine cap at the 5' end of a nascent messenger RNA transcript.	got7fsn_ti	mRNA cap binding				This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to.	GO:0000339				True				molecular_function											owl:Class	
GO:1904772	biolink:NamedThing	response to tetrachloromethane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus.	got7fsn_ti	response to CCL4|response to carbon tetrachloride						sl	2015-10-28T20:59:15Z						biological_process											owl:Class	
GO:1904582	biolink:NamedThing	positive regulation of intracellular mRNA localization	Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.	got7fsn_ti	up-regulation of establishment and maintenance of intracellular RNA localization|upregulation of mRNA localization, intracellular|up-regulation of mRNA positioning, intracellular|positive regulation of intracellular mRNA localisation|up-regulation of intracellular mRNA localization|upregulation of mRNA positioning, intracellular|up regulation of mRNA localization, intracellular|upregulation of intracellular mRNA localization|activation of intracellular mRNA localisation|up-regulation of mRNA localization, intracellular|upregulation of intracellular mRNA positioning|up-regulation of intracellular mRNA positioning|up regulation of establishment and maintenance of intracellular RNA localization|positive regulation of mRNA positioning, intracellular|activation of mRNA localization, intracellular|positive regulation of establishment and maintenance of intracellular RNA localization|activation of establishment and maintenance of intracellular RNA localization|up regulation of intracellular mRNA positioning|up regulation of mRNA positioning, intracellular|activation of intracellular mRNA localization|upregulation of establishment and maintenance of intracellular RNA localization|activation of intracellular mRNA positioning|activation of mRNA positioning, intracellular|upregulation of intracellular mRNA localisation|up regulation of intracellular mRNA localisation|up regulation of intracellular mRNA localization|positive regulation of mRNA localization, intracellular|up-regulation of intracellular mRNA localisation|positive regulation of intracellular mRNA positioning						sl	2015-08-19T23:40:38Z						biological_process											owl:Class	
GO:0030616	biolink:NamedThing	obsolete transforming growth factor beta receptor, common-partner cytoplasmic mediator activity	OBSOLETE. A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription.	got7fsn_ti	TGF-beta receptor, common-partner cytoplasmic mediator activity|co-SMAD protein|TGFbeta receptor, common-partner cytoplasmic mediator activity|common-mediator SMAD protein|common mediator SMAD protein|common partner SMAD protein|common-partner SMAD protein	https://github.com/geneontology/go-ontology/issues/16202			This term was obsoleted because it is redundant with other terms.	GO:0003712|GO:0000981				True				molecular_function											owl:Class	
GO:1900258	biolink:NamedThing	positive regulation of beta1-adrenergic receptor activity	Any process that activates or increases the frequency, rate or extent of beta1-adrenergic receptor activity.	got7fsn_ti	upregulation of beta1-adrenergic receptor activity|up-regulation of beta1 adrenoceptor|up regulation of beta1-adrenergic receptor activity|activation of beta1-adrenergic receptor activity|positive regulation of beta1 adrenoceptor|activation of beta1 adrenoceptor|up regulation of beta1 adrenoceptor|up-regulation of beta1-adrenergic receptor activity|upregulation of beta1 adrenoceptor						tb	2012-04-03T10:59:49Z						biological_process											owl:Class	
GO:0004254	biolink:NamedThing	obsolete acylaminoacyl-peptidase activity	OBSOLETE. Catalysis of the reaction: acylaminoacyl-peptide + H2O = acylamino acid + peptide.	got7fsn_ti	N-acylpeptide hydrolase activity|N-formylmethionine (fMet) aminopeptidase activity|acylamino-acid-releasing enzyme activity|acylaminoacyl-peptidase activity|alpha-N-acylpeptide hydrolase activity			GO:0004252						True				molecular_function											owl:Class	
GO:0042452	biolink:NamedThing	deoxyguanosine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.	got7fsn_ti	deoxyguanosine anabolism|deoxyguanosine biosynthesis|deoxyguanosine synthesis|deoxyguanosine formation													biological_process											owl:Class	
GO:0051770	biolink:NamedThing	positive regulation of nitric-oxide synthase biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.	got7fsn_ti	activation of nitric-oxide synthase biosynthetic process|positive regulation of NOS biosynthetic process|stimulation of nitric-oxide synthase 2 biosynthetic process|stimulation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase (type 2) biosynthetic process|activation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NOS2 synthase biosynthesis|up regulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of nitric-oxide synthase (type II) biosynthetic process|positive regulation of nitric-oxide synthase (type 2) biosynthesis|positive regulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NOS biosynthesis|up-regulation of nitric-oxide synthase biosynthetic process|positive regulation of NOS2 synthase biosynthetic process|positive regulation of NO synthase biosynthetic process|upregulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NO synthase biosynthesis|positive regulation of nitric-oxide synthase (type II) biosynthesis|up regulation of nitric-oxide synthase biosynthetic process|upregulation of nitric-oxide synthase biosynthetic process|up-regulation of nitric-oxide synthase 2 biosynthetic process										GO:0051773			biological_process											owl:Class	
GO:1904000	biolink:NamedThing	positive regulation of eating behavior	Any process that activates or increases the frequency, rate or extent of eating behavior.	got7fsn_ti	up regulation of eating behavior|up-regulation of eating behavior|up-regulation of eating behaviour|upregulation of eating behaviour|positive regulation of eating behaviour|activation of eating behavior|activation of eating behaviour|upregulation of eating behavior|up regulation of eating behaviour						sl	2015-03-05T20:40:35Z						biological_process											owl:Class	
GO:0019348	biolink:NamedThing	dolichol metabolic process	The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.	got7fsn_ti	dolichol metabolism													biological_process											owl:Class	
GO:1904684	biolink:NamedThing	negative regulation of metalloendopeptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity.	got7fsn_ti	negative regulation of metalloendoprotease activity|downregulation of metalloendoprotease activity|down-regulation of metalloendoprotease activity|down regulation of metalloendoprotease activity|down-regulation of metalloendoproteinase activity|down regulation of metalloendoproteinase activity|inhibition of metalloendopeptidase activity|inhibition of metalloendoproteinase activity|inhibition of metalloendoprotease activity|down-regulation of metalloendopeptidase activity|down regulation of metalloendopeptidase activity|negative regulation of metalloendoproteinase activity|downregulation of metalloendopeptidase activity|downregulation of metalloendoproteinase activity						rph	2015-09-24T11:18:21Z						biological_process											owl:Class	
GO:1904709	biolink:NamedThing	negative regulation of granulosa cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process.	got7fsn_ti	down-regulation of granulosa cell apoptosis|down-regulation of granulosa cell apoptotic process|downregulation of granulosa cell of ovary apoptotic process|down-regulation of granulosa cell of ovary apoptotic process|negative regulation of granulosa cell of ovary apoptotic process|downregulation of granulosa cell apoptotic process|inhibition of granulosa cell of ovary apoptosis|downregulation of granulosa cell apoptosis|inhibition of granulosa cell apoptosis|inhibition of granulosa cell of ovary apoptotic process|down regulation of granulosa cell of ovary apoptotic process|downregulation of granulosa cell of ovary apoptosis|down regulation of granulosa cell apoptosis|down-regulation of granulosa cell of ovary apoptosis|negative regulation of granulosa cell of ovary apoptosis|inhibition of granulosa cell apoptotic process|down regulation of granulosa cell of ovary apoptosis|negative regulation of granulosa cell apoptosis|down regulation of granulosa cell apoptotic process						sl	2015-10-01T16:09:45Z						biological_process											owl:Class	
GO:1905747	biolink:NamedThing	negative regulation of saliva secretion	Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion.	got7fsn_ti	down-regulation of salivation|down regulation of salivation|negative regulation of salivation|inhibition of saliva secretion|downregulation of salivation|downregulation of saliva secretion|down-regulation of saliva secretion|down regulation of saliva secretion|inhibition of salivation						pga	2016-12-09T10:24:00Z						biological_process											owl:Class	
GO:0052191	biolink:NamedThing	obsolete positive regulation by symbiont of host phagocytosis	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	up regulation by symbiont of host phagocytosis|stimulation by symbiont of host phagocytosis|upregulation by symbiont of host phagocytosis|activation by symbiont of host phagocytosis|up-regulation by symbiont of host phagocytosis	https://github.com/geneontology/go-ontology/issues/18562			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0051623	biolink:NamedThing	positive regulation of norepinephrine uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.	got7fsn_ti	positive regulation of levarterenol uptake|stimulation of norepinephrine uptake|up regulation of norepinephrine uptake|activation of norepinephrine uptake|up-regulation of norepinephrine uptake|positive regulation of noradrenaline uptake|upregulation of norepinephrine uptake|positive regulation of norepinephrine import													biological_process											owl:Class	
GO:1904084	biolink:NamedThing	obsolete negative regulation of epiboly	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of epiboly.	got7fsn_ti	negative regulation of epiboly|down regulation of epiboly|down-regulation of epiboly|inhibition of epiboly|downregulation of epiboly				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2015-03-25T10:53:40Z		True				biological_process											owl:Class	
GO:0023037	biolink:NamedThing	obsolete signal initiation by light	OBSOLETE. The process in which a light signal causes activation of a receptor.	got7fsn_ti	signal initiation by light				This term was made obsolete because the meaning of the term is ambiguous.	GO:0010018|GO:0009881|GO:0010161|GO:0009785|GO:0010017		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1902978	biolink:NamedThing	premeiotic DNA replication termination	Any DNA replication termination involved in meiotic cell cycle DNA replication.	got7fsn_ti	DNA replication termination involved in meiotic DNA replication|DNA replication termination involved in meiotic cell cycle DNA replication						jl	2014-05-06T19:19:43Z						biological_process											owl:Class	
GO:0075315	biolink:NamedThing	positive regulation of basidium development	Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.	got7fsn_ti														biological_process											owl:Class	
GO:1903900	biolink:NamedThing	regulation of viral life cycle	Any process that modulates the frequency, rate or extent of viral life cycle.	got7fsn_ti	regulation of viral replication|regulation of viral assembly, maturation, egress, and release|regulation of viral infectious cycle|regulation of lytic viral life cycle						pga	2015-02-09T10:22:07Z						biological_process											owl:Class	
GO:0018979	biolink:NamedThing	trichloroethylene metabolic process	The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.	got7fsn_ti	TCE metabolic process|trichloroethene metabolic process|TCE metabolism|trichloroethylene metabolism|trichloroethene metabolism											UM-BBD_pathwayID:tce		biological_process											owl:Class	
GO:0072713	biolink:NamedThing	cellular response to thiabendazole	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.	got7fsn_ti	cellular response to TBZ						mah	2012-04-11T04:24:19Z						biological_process											owl:Class	
GO:1902914	biolink:NamedThing	regulation of protein polyubiquitination	Any process that modulates the frequency, rate or extent of protein polyubiquitination.	got7fsn_ti	regulation of protein polyubiquitylation|regulation of protein polyubiquitinylation|regulation of polyubiquitin						di	2014-04-18T22:09:52Z						biological_process											owl:Class	
GO:0090145	biolink:NamedThing	obsolete mitochondrial nucleoid organization involved in mitochondrial fission	OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid that contributes to mitochondrial division.	got7fsn_ti	mitochondrial nucleoid organisation involved in mitochondrial fission	https://github.com/geneontology/go-ontology/issues/18417			This term was obsoleted because it represented a phenotype.	GO:0000002|GO:0000266	tb	2009-12-08T02:39:34Z		True				biological_process											owl:Class	
GO:1900491	biolink:NamedThing	regulation of [4Fe-4S] cluster assembly	Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly.	got7fsn_ti	regulation of [4Fe-4S] cluster biosynthetic process|regulation of 4Fe-4S cluster assembly						tt	2012-05-02T03:48:49Z						biological_process											owl:Class	
GO:1903838	biolink:NamedThing	negative regulation of mRNA 3'-UTR binding	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding.	got7fsn_ti	down regulation of mRNA 3'-UTR binding|inhibition of mRNA 3'-UTR binding|inhibition of mRNA 3' UTR binding|down-regulation of mRNA 3'-UTR binding|down-regulation of mRNA 3' UTR binding|downregulation of mRNA 3' UTR binding|negative regulation of mRNA 3' UTR binding|downregulation of mRNA 3'-UTR binding|down regulation of mRNA 3' UTR binding						als	2015-01-22T11:54:08Z						biological_process											owl:Class	
GO:0051822	biolink:NamedThing	obsolete dissemination or transmission of organism from other organism by vector involved in symbiotic interaction	OBSOLETE. The movement of an organism from a second organism to another place in the environment by means of a vector, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism, and the vector organism is often an insect or an animal.	got7fsn_ti	dissemination or transmission of organism from other organism by vector during symbiotic interaction				This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.					True				biological_process											owl:Class	
GO:1902993	biolink:NamedThing	positive regulation of amyloid precursor protein catabolic process	Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process.	got7fsn_ti	upregulation of amyloid precursor protein catabolic process|up-regulation of APP catabolic process|positive regulation of amyloid precursor protein degradation|activation of amyloid precursor protein catabolic process|positive regulation of APP catabolic process|activation of APP catabolism|up-regulation of APP catabolism|up regulation of amyloid precursor protein breakdown|upregulation of APP catabolic process|up-regulation of amyloid precursor protein degradation|activation of amyloid precursor protein catabolism|upregulation of amyloid precursor protein catabolism|positive regulation of amyloid precursor protein catabolism|activation of amyloid precursor protein breakdown|upregulation of APP catabolism|up regulation of amyloid precursor protein catabolic process|positive regulation of APP catabolism|up-regulation of amyloid precursor protein catabolism|up regulation of amyloid precursor protein catabolism|upregulation of amyloid precursor protein degradation|up-regulation of amyloid precursor protein catabolic process|up regulation of APP catabolic process|up regulation of APP catabolism|positive regulation of amyloid precursor protein breakdown|upregulation of amyloid precursor protein breakdown|activation of amyloid precursor protein degradation|activation of APP catabolic process|up regulation of amyloid precursor protein degradation|up-regulation of amyloid precursor protein breakdown						rl	2014-05-08T14:21:16Z						biological_process											owl:Class	
GO:0019342	biolink:NamedThing	trypanothione biosynthetic process	The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.	got7fsn_ti	trypanothione synthesis|trypanothione anabolism|trypanothione biosynthesis|trypanothione formation											MetaCyc:TRYPANOSYN-PWY		biological_process											owl:Class	
GO:1903239	biolink:NamedThing	obsolete regulation of positive regulation of the force of heart contraction by chemical signal	OBSOLETE. Any process that modulates the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal.	got7fsn_ti	regulation of positive regulation of the force of heart contraction by chemical signal|regulation of positive regulation of the force of heart muscle contraction by chemical signal				This term was obsoleted at the TermGenie Gatekeeper stage.		rl	2014-07-31T17:00:17Z		True				biological_process											owl:Class	
GO:0004238	biolink:NamedThing	obsolete meprin A activity	OBSOLETE. Catalysis of the hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues.	got7fsn_ti	PABA-peptide hydrolase activity|meprin|N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase activity|endopeptidase-2 activity|PPH|meprin A activity|meprin-a			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905920	biolink:NamedThing	positive regulation of CoA-transferase activity	Any process that activates or increases the frequency, rate or extent of CoA-transferase activity.	got7fsn_ti	activation of CoA-transferase activity|up regulation of CoA-transferase activity|upregulation of CoA-transferase activity|up-regulation of CoA-transferase activity						bc	2017-02-08T13:01:04Z						biological_process											owl:Class	
GO:1903198	biolink:NamedThing	regulation of L-dopa decarboxylase activity	Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity.	got7fsn_ti	regulation of DDC activity|regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|regulation of DOPA decarboxylase activity						bf	2014-07-21T09:32:31Z						biological_process											owl:Class	
GO:0051201	biolink:NamedThing	negative regulation of prosthetic group metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.	got7fsn_ti	down-regulation of prosthetic group metabolic process|negative regulation of coenzyme and prosthetic group metabolic process|inhibition of prosthetic group metabolic process|down regulation of prosthetic group metabolic process|negative regulation of prosthetic group metabolism|negative regulation of coenzyme and prosthetic group metabolism|downregulation of prosthetic group metabolic process													biological_process											owl:Class	
GO:0072126	biolink:NamedThing	positive regulation of glomerular mesangial cell proliferation	Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.	got7fsn_ti							mah	2010-02-22T01:49:31Z						biological_process											owl:Class	
GO:1902833	biolink:NamedThing	positive regulation of cell proliferation in dorsal spinal cord	Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord.	got7fsn_ti	upregulation of cell proliferation in dorsal spinal cord|activation of cell proliferation in dorsal spinal cord|up-regulation of cell proliferation in dorsal spinal cord|up regulation of cell proliferation in dorsal spinal cord						mr	2014-03-31T17:43:33Z						biological_process											owl:Class	
GO:0060810	biolink:NamedThing	intracellular mRNA localization involved in pattern specification process	Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.	got7fsn_ti	intracellular mRNA localisation involved in pattern specification process						dph	2009-08-07T09:19:58Z						biological_process											owl:Class	
GO:1900320	biolink:NamedThing	positive regulation of methane biosynthetic process from dimethylamine	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine.	got7fsn_ti	up-regulation of methane biosynthetic process from dimethylamine|upregulation of methane biosynthetic process from dimethylamine|up regulation of methane biosynthetic process from dimethylamine|activation of methane biosynthetic process from dimethylamine						tt	2012-04-06T01:43:40Z						biological_process											owl:Class	
GO:0014875	biolink:NamedThing	detection of muscle activity involved in regulation of muscle adaptation	The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.	got7fsn_ti	detection of fatigue													biological_process											owl:Class	
GO:0031406	biolink:NamedThing	carboxylic acid binding	Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-).	got7fsn_ti														molecular_function											owl:Class	
GO:0062084	biolink:NamedThing	regulation of capsule polysaccharide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.	got7fsn_ti							dph	2018-10-31T15:58:08Z						biological_process											owl:Class	
GO:0010263	biolink:NamedThing	tricyclic triterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings.	got7fsn_ti	tricyclic triterpenoid formation|tricyclic triterpenoid anabolism|tricyclic triterpenoid synthesis|tricyclic triterpenoid biosynthesis													biological_process											owl:Class	
GO:0006792	biolink:NamedThing	regulation of sulfur utilization	Any process that modulates the frequency, rate or extent of sulfur utilization.	got7fsn_ti	regulation of sulphur utilization													biological_process											owl:Class	
GO:0019741	biolink:NamedThing	pentacyclic triterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.	got7fsn_ti	pentacyclic triterpenoid catabolism|pentacyclic triterpenoid breakdown|pentacyclic triterpenoid degradation													biological_process											owl:Class	
GO:0033091	biolink:NamedThing	positive regulation of immature T cell proliferation	Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:1900414	biolink:NamedThing	obsolete regulation of cytokinesis by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cytokinesis.	got7fsn_ti							mah	2012-04-20T03:42:13Z		True				biological_process											owl:Class	
GO:0100069	biolink:NamedThing	obsolete negative regulation of neuron apoptotic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates neuron apoptotic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1904206	biolink:NamedThing	positive regulation of skeletal muscle hypertrophy	Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy.	got7fsn_ti	activation of skeletal muscle hypertrophy|upregulation of skeletal muscle hypertrophy|up-regulation of skeletal muscle hypertrophy|up regulation of skeletal muscle hypertrophy						sl	2015-05-08T17:38:25Z						biological_process											owl:Class	
GO:1901831	biolink:NamedThing	all-trans-neoxanthin metabolic process	The chemical reactions and pathways involving all-trans-neoxanthin.	got7fsn_ti	neoxanthin metabolic process|all-trans-neoxanthin metabolism|neoxanthin metabolism						yaf	2013-01-22T12:43:46Z						biological_process											owl:Class	
GO:0031137	biolink:NamedThing	regulation of conjugation with cellular fusion	Any process that modulates the rate or frequency of conjugation with cellular fusion.	got7fsn_ti														biological_process											owl:Class	
GO:1904120	biolink:NamedThing	positive regulation of otic vesicle morphogenesis	Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis.	got7fsn_ti	up regulation of otic vesicle morphogenesis|activation of otic vesicle morphogenesis|upregulation of otic vesicle morphogenesis|up-regulation of otic vesicle morphogenesis						pga	2015-04-07T14:01:08Z						biological_process											owl:Class	
GO:0072408	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000335	biolink:NamedThing	negative regulation of transposition, DNA-mediated	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA transposition.	got7fsn_ti	down regulation of DNA transposition|negative regulation of DNA transposition|downregulation of DNA transposition|inhibition of DNA transposition|down-regulation of DNA transposition													biological_process											owl:Class	
GO:1901311	biolink:NamedThing	obsolete regulation of gene expression involved in extracellular matrix organization	OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression involved in extracellular matrix organization.	got7fsn_ti	regulation of expression of extracellular matrix proteins|regulation of extracellular matrix protein production				This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization.	GO:0010468	vk	2012-08-22T09:18:13Z		True				biological_process											owl:Class	
GO:1904725	biolink:NamedThing	obsolete TFIIB-class transcription factor binding involved in negative regulation of transcription	OBSOLETE. Any TFIIB-class transcription factor binding that is involved in negative regulation of DNA-templated transcription.	got7fsn_ti	TFIIB-class transcription factor binding involved in down-regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in inhibition of gene-specific transcription|TFIIB-class transcription factor binding involved in down regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in downregulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-templated|TFIIB-class transcription factor binding involved in downregulation of gene-specific transcription|TFIIB-class transcription factor binding involved in down regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in transcription repressor activity|TFIIB-class transcription factor binding involved in inhibition of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of cellular transcription, DNA-dependent|TFIIB-class transcription factor binding involved in down-regulation of gene-specific transcription				The reason for obsoletion is that this term represents a GO-CAM model.		tb	2015-10-13T19:49:39Z		True				molecular_function											owl:Class	
GO:1902743	biolink:NamedThing	regulation of lamellipodium organization	Any process that modulates the frequency, rate or extent of lamellipodium organization.	got7fsn_ti							als	2014-02-28T16:27:30Z						biological_process											owl:Class	
GO:0010416	biolink:NamedThing	arabinoxylan-containing compound metabolic process	The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units.	got7fsn_ti	arabinoxylan metabolic process|arabinoxylan metabolism													biological_process											owl:Class	
GO:0005205	biolink:NamedThing	obsolete chondroitin sulfate/dermatan sulfate proteoglycan	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	chondroitin sulphate/dermatan sulphate proteoglycan|chondroitin sulfate/dermatan sulfate proteoglycan				This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function.					True				molecular_function											owl:Class	
GO:0019720	biolink:NamedThing	Mo-molybdopterin cofactor metabolic process	The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.	got7fsn_ti	Mo-molybdopterin cofactor metabolism|Moco metabolic process|Moco metabolism													biological_process											owl:Class	
GO:1904634	biolink:NamedThing	negative regulation of glomerular visceral epithelial cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.	got7fsn_ti	negative regulation of podocyte apoptotic process|down-regulation of glomerular podocyte apoptotic process|down regulation of glomerular podocyte apoptosis|downregulation of glomerular podocyte apoptotic process|inhibition of glomerular podocyte apoptotic process|negative regulation of glomerular podocyte apoptosis|down regulation of glomerular visceral epithelial cell apoptotic process|negative regulation of podocyte apoptosis|downregulation of glomerular visceral epithelial cell apoptosis|inhibition of glomerular visceral epithelial cell apoptosis|down regulation of glomerular visceral epithelial cell apoptosis|inhibition of podocyte apoptotic process|inhibition of glomerular podocyte apoptosis|inhibition of glomerular visceral epithelial cell apoptotic process|downregulation of glomerular podocyte apoptosis|down regulation of glomerular podocyte apoptotic process|down regulation of podocyte apoptotic process|downregulation of glomerular visceral epithelial cell apoptotic process|down-regulation of glomerular visceral epithelial cell apoptosis|down-regulation of glomerular visceral epithelial cell apoptotic process|down-regulation of podocyte apoptotic process|inhibition of podocyte apoptosis|negative regulation of glomerular visceral epithelial cell apoptosis|negative regulation of glomerular podocyte apoptotic process|downregulation of podocyte apoptotic process|down-regulation of glomerular podocyte apoptosis|down regulation of podocyte apoptosis|down-regulation of podocyte apoptosis|downregulation of podocyte apoptosis						sl	2015-08-28T14:14:50Z						biological_process											owl:Class	
GO:1902856	biolink:NamedThing	negative regulation of non-motile cilium assembly	Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly.	got7fsn_ti	down-regulation of sensory cilium biogenesis|down-regulation of sensory cilium assembly|inhibition of sensory cilium biogenesis|down-regulation of nonmotile primary cilia assembly|negative regulation of sensory cilium assembly|down regulation of nonmotile primary cilium assembly|down regulation of nonmotile primary cilia assembly|down-regulation of nonmotile primary cilium assembly|negative regulation of nonmotile primary cilium assembly|inhibition of sensory cilium assembly|downregulation of sensory cilium biogenesis|inhibition of immotile primary cilium assembly|downregulation of nonmotile primary cilia assembly|down regulation of sensory cilium assembly|down regulation of immotile primary cilium assembly|downregulation of sensory cilium assembly|down-regulation of immotile primary cilium assembly|inhibition of nonmotile primary cilium assembly|downregulation of nonmotile primary cilium assembly|down regulation of sensory cilium biogenesis|negative regulation of immotile primary cilium assembly|downregulation of immotile primary cilium assembly|negative regulation of nonmotile primary cilia assembly|negative regulation of sensory cilium biogenesis|inhibition of nonmotile primary cilia assembly						kmv	2014-04-02T15:42:17Z						biological_process											owl:Class	
GO:1990449	biolink:NamedThing	obsolete amylin receptor	OBSOLETE. A G protein-coupled signalling receptor complex consisting of the calcitonin receptor and a receptor activity-modifying protein (RAMP). Amylin is produced in beta-islet cells of the pancreas. It is implicated in selective inhibition of insulin-stimulated glucose utilization and glycogen deposition in muscle, gastric emptying, gastric acid secretion, postprandial glucagon secretion and food intake and aids weight loss.	got7fsn_ti	CALCR-RAMP3 receptor|amylin receptor|CALCR-RAMP2 receptor|AMY1 receptor|AMY2 receptor|AMY3 receptor|CALCR-RAMP1 receptor				An example of this is CALCR in human (P30988) in PMID:10871269.		bhm	2014-08-06T10:21:37Z		True				cellular_component											owl:Class	
GO:0030710	biolink:NamedThing	regulation of border follicle cell delamination	Any process that regulates the frequency, rate or extent of border cell delamination.	got7fsn_ti	regulation of border cell delamination													biological_process											owl:Class	
GO:0031560	biolink:NamedThing	cellular bud neck polarisome	Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.	got7fsn_ti														cellular_component											owl:Class	
GO:0071225	biolink:NamedThing	cellular response to muramyl dipeptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.	got7fsn_ti							mah	2009-12-03T01:41:23Z						biological_process											owl:Class	
GO:0002677	biolink:NamedThing	negative regulation of chronic inflammatory response	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response.	got7fsn_ti	downregulation of chronic inflammatory response|down-regulation of chronic inflammatory response|inhibition of chronic inflammatory response|down regulation of chronic inflammatory response													biological_process											owl:Class	
GO:1904765	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to maltose	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a maltose stimulus.	got7fsn_ti	activation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of global transcription from Pol II promoter involved in cellular response to maltose stimulus|stimulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up-regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|activation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from Pol II promoter involved in cellular response to maltose stimulus|upregulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|upregulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from RNA polymerase II promoter, global involved in cellular response to maltose stimulus|up regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|stimulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus						mah	2015-10-26T16:42:15Z						biological_process											owl:Class	
GO:0062038	biolink:NamedThing	positive regulation of pheromone response MAPK cascade	Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.	got7fsn_ti							dph	2018-05-01T13:00:56Z						biological_process											owl:Class	
GO:0009049	biolink:NamedThing	obsolete aspartic-type signal peptidase activity	OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by an aspartic endopeptidase mechanism.	got7fsn_ti	aspartic-type signal peptidase activity			GO:0004190	This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products.					True				molecular_function											owl:Class	
GO:1903926	biolink:NamedThing	cellular response to bisphenol A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.	got7fsn_ti							sl	2015-02-11T00:17:04Z						biological_process											owl:Class	
GO:0018927	biolink:NamedThing	obsolete methionine and threonine metabolic process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	methionine and threonine metabolic process				This term was made obsolete because its use of 'and' was causing violations to the true-path rule.	GO:0006566|GO:0006555				True				biological_process											owl:Class	
GO:0005281	biolink:NamedThing	obsolete general amino acid permease activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	general amino acid transporter|general amino acid permease activity			GO:0015171	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0033599	biolink:NamedThing	regulation of mammary gland epithelial cell proliferation	Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0001969	biolink:NamedThing	regulation of activation of membrane attack complex	Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.	got7fsn_ti	regulation of MAC assembly|regulation of MAC formation|regulation of membrane attack complex formation|regulation of activation of terminal complement complex|regulation of membrane attack complex assembly|regulation of activation of the terminal complement cascade|regulation of activation of MAC|regulation of activation of TCC													biological_process											owl:Class	
GO:1903207	biolink:NamedThing	regulation of hydrogen peroxide-induced neuron death	Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced neuron death.	got7fsn_ti	regulation of neuronal cell death in response to hydrogen peroxide|regulation of neuron death in response to hydrogen peroxide|regulation of neuron death in response to H2O2						bf	2014-07-21T16:27:05Z						biological_process											owl:Class	
GO:0075212	biolink:NamedThing	obsolete positive regulation of transmembrane receptor-mediated cAMP signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0060862	biolink:NamedThing	negative regulation of floral organ abscission	Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.	got7fsn_ti							dph	2009-08-12T04:05:23Z						biological_process											owl:Class	
GO:0009140	biolink:NamedThing	pyrimidine nucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside diphosphate breakdown|pyrimidine nucleoside diphosphate degradation|pyrimidine nucleoside diphosphate catabolism													biological_process											owl:Class	
GO:0016542	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010545	biolink:NamedThing	obsolete Hsp90 protein regulator activity	OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsp90.	got7fsn_ti	Hsp90 protein regulator activity			GO:0051879	This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp90 protein activity'.	GO:0006457|GO:0051082|GO:0051787				True				molecular_function											owl:Class	
GO:1904470	biolink:NamedThing	regulation of endothelin production	Any process that modulates the frequency, rate or extent of endothelin production.	got7fsn_ti	regulation of endothelin secretion|regulation of EDN3 secretion|regulation of endothelin-1 secretion|regulation of EDN1 secretion|regulation of EDN2 secretion|regulation of endothelin-2 secretion|regulation of endothelin-3 secretion						sl	2015-07-09T19:57:57Z						biological_process											owl:Class	
GO:0070272	biolink:NamedThing	obsolete proton-transporting ATP synthase complex biogenesis	OBSOLETE. The biogenesis of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	got7fsn_ti	F-type ATPase complex biogenesis	https://github.com/geneontology/go-ontology/issues/15173			The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.					True				biological_process											owl:Class	
GO:1900889	biolink:NamedThing	positive regulation of pentadecane biosynthetic process	Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process.	got7fsn_ti	activation of pentadecane anabolism|upregulation of pentadecane anabolism|upregulation of pentadecane biosynthesis|positive regulation of pentadecane biosynthesis|up regulation of pentadecane synthesis|activation of pentadecane synthesis|up regulation of pentadecane formation|positive regulation of pentadecane synthesis|up-regulation of pentadecane biosynthesis|up-regulation of pentadecane biosynthetic process|positive regulation of pentadecane anabolism|activation of pentadecane formation|up regulation of pentadecane biosynthesis|upregulation of pentadecane biosynthetic process|up regulation of pentadecane anabolism|upregulation of pentadecane formation|activation of pentadecane biosynthetic process|up regulation of pentadecane biosynthetic process|positive regulation of pentadecane formation|upregulation of pentadecane synthesis|up-regulation of pentadecane formation|up-regulation of pentadecane synthesis|activation of pentadecane biosynthesis|up-regulation of pentadecane anabolism						tt	2012-06-13T03:04:04Z						biological_process											owl:Class	
GO:0070103	biolink:NamedThing	regulation of interleukin-6-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6-mediated binding to a cell surface receptor.	got7fsn_ti	regulation of interleukin-6-mediated signalling pathway|regulation of IL-6-mediated signaling pathway													biological_process											owl:Class	
GO:1902987	biolink:NamedThing	negative regulation of lysine biosynthetic process via aminoadipic acid	Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.	got7fsn_ti	inhibition of lysine biosynthesis, aminoadipic pathway|down-regulation of lysine anabolism via aminoadipic acid|negative regulation of lysine anabolism via aminoadipic acid|negative regulation of lysine biosynthetic process, aminoadipic pathway|downregulation of lysine biosynthetic process via aminoadipic acid|down regulation of lysine formation via aminoadipic acid|inhibition of lysine biosynthetic process via aminoadipic acid|negative regulation of lysine biosynthetic process, aminoadipic acid pathway|down-regulation of lysine biosynthetic process, aminoadipic pathway|down regulation of lysine biosynthesis, aminoadipic acid pathway|down regulation of lysine anabolism via aminoadipic acid|inhibition of lysine synthesis via aminoadipic acid|inhibition of lysine formation via aminoadipic acid|down regulation of lysine biosynthetic process, aminoadipic pathway|downregulation of lysine biosynthetic process, aminoadipic pathway|down-regulation of lysine biosynthesis, aminoadipic pathway|downregulation of lysine anabolism via aminoadipic acid|down regulation of lysine biosynthesis, aminoadipic pathway|negative regulation of lysine synthesis via aminoadipic acid|downregulation of lysine synthesis via aminoadipic acid|down-regulation of lysine formation via aminoadipic acid|negative regulation of lysine biosynthesis, aminoadipic acid pathway|down-regulation of lysine biosynthetic process, aminoadipic acid pathway|downregulation of lysine biosynthesis, aminoadipic pathway|down regulation of lysine biosynthetic process, aminoadipic acid pathway|down regulation of lysine synthesis via aminoadipic acid|inhibition of lysine biosynthetic process, aminoadipic acid pathway|negative regulation of lysine biosynthesis, aminoadipic pathway|inhibition of lysine anabolism via aminoadipic acid|down-regulation of lysine biosynthetic process via aminoadipic acid|downregulation of lysine formation via aminoadipic acid|downregulation of lysine biosynthetic process, aminoadipic acid pathway|downregulation of lysine biosynthesis, aminoadipic acid pathway|inhibition of lysine biosynthesis, aminoadipic acid pathway|negative regulation of lysine formation via aminoadipic acid|inhibition of lysine biosynthetic process, aminoadipic pathway|down regulation of lysine biosynthetic process via aminoadipic acid|down-regulation of lysine biosynthesis, aminoadipic acid pathway|down-regulation of lysine synthesis via aminoadipic acid						al	2014-05-07T08:07:15Z						biological_process											owl:Class	
GO:1900883	biolink:NamedThing	17-methylnonadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene.	got7fsn_ti	17-methylnonadec-1-ene formation|17-methylnonadec-1-ene biosynthesis|17-methylnonadec-1-ene anabolism|17-methylnonadec-1-ene synthesis						tt	2012-06-13T02:35:59Z						biological_process											owl:Class	
GO:0097305	biolink:NamedThing	response to alcohol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.	got7fsn_ti	process resulting in tolerance to alcohol						pr	2012-05-15T03:48:45Z			GO:1990335			biological_process											owl:Class	
GO:1905373	biolink:NamedThing	ceramide phosphoethanolamine biosynthetic process	The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine.	got7fsn_ti	ceramide phosphoethanolamine biosynthesis|ceramide phosphoethanolamine synthesis|ceramide phosphoethanolamine formation|ceramide phosphoethanolamine anabolism						hjd	2016-08-16T17:11:12Z						biological_process											owl:Class	
GO:2000127	biolink:NamedThing	positive regulation of octopamine or tyramine signaling pathway	Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway.	got7fsn_ti	positive regulation of octopamine or tyramine signalling pathway|positive regulation of octopamine/tyramine signaling pathway						mah	2010-09-29T09:27:19Z						biological_process											owl:Class	
GO:0019572	biolink:NamedThing	L-arabinose catabolic process	The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose.	got7fsn_ti	L-arabinose breakdown|L-arabinose catabolism|L-arabinose degradation													biological_process											owl:Class	
GO:0009194	biolink:NamedThing	pyrimidine ribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside diphosphate anabolism|pyrimidine ribonucleoside diphosphate formation|pyrimidine ribonucleoside diphosphate biosynthesis|pyrimidine ribonucleoside diphosphate synthesis													biological_process											owl:Class	
GO:0010703	biolink:NamedThing	obsolete negative regulation of histolysis	OBSOLETE. Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.	got7fsn_ti	down regulation of histolysis|down-regulation of histolysis|downregulation of histolysis|inhibition of histolysis				This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0012501|GO:0008219				True				biological_process											owl:Class	
GO:0009134	biolink:NamedThing	nucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	nucleoside diphosphate degradation|nucleoside diphosphate catabolism|nucleoside diphosphate breakdown													biological_process											owl:Class	
GO:0075153	biolink:NamedThing	obsolete regulation of transmembrane receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont transmembrane receptor-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0072737	biolink:NamedThing	response to diamide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	got7fsn_ti	response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide						mah	2012-07-17T10:33:00Z						biological_process											owl:Class	
GO:1904781	biolink:NamedThing	positive regulation of protein localization to centrosome	Any process that activates or increases the frequency, rate or extent of protein localization to centrosome.	got7fsn_ti	activation of protein localisation to centrosome|positive regulation of protein localisation to centrosome|up regulation of protein localization to centrosome|up-regulation of protein localization to centrosome|upregulation of protein localisation to centrosome|activation of protein localization to centrosome|up regulation of protein localisation to centrosome|upregulation of protein localization to centrosome|up-regulation of protein localisation to centrosome				An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype).		es	2015-10-30T11:54:53Z						biological_process											owl:Class	
GO:1901735	biolink:NamedThing	(R)-mevalonic acid metabolic process	The chemical reactions and pathways involving (R)-mevalonic acid.	got7fsn_ti	(R) mevalonate metabolism|(R)-mevalonic acid metabolism						yaf	2013-01-11T11:25:50Z						biological_process											owl:Class	
GO:1902927	biolink:NamedThing	inulin catabolic process	The chemical reactions and pathways resulting in the breakdown of inulin.	got7fsn_ti	inulin degradation|inulin breakdown|inulin catabolism				SUC2 in S. cerevisiae strain JZ1C in PMID:23104410.		se	2014-04-21T23:54:45Z						biological_process											owl:Class	
GO:1990958	biolink:NamedThing	obsolete response to thyrotropin-releasing hormone	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.	got7fsn_ti	response to TRH				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-06-06T21:07:34Z		True				biological_process											owl:Class	
GO:0006072	biolink:NamedThing	glycerol-3-phosphate metabolic process	The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.	got7fsn_ti	glycerol-3-phosphate metabolism													biological_process											owl:Class	
GO:0045586	biolink:NamedThing	regulation of gamma-delta T cell differentiation	Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation.	got7fsn_ti	regulation of gamma-delta T lymphocyte differentiation|regulation of gamma-delta T-cell differentiation|regulation of gamma-delta T cell development|regulation of gamma-delta T-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0120080	biolink:NamedThing	obsolete negative regulation of microfilament motor activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of microfilament motor activity.	got7fsn_ti	inhibition of actin-dependent ATPase activity|negative regulation of actin filament motor activity|negative regulation of actin-activated ATPase activity|down regulation of actin-activated ATPase activity|down regulation of actin-dependent ATPase activity|negative regulation of actin-dependent ATPase activity|negative regulation of muscle motor activity|inhibition of actin-activated ATPase activity|negative regulation of actin-filament motor activity|negative regulation of myosin ATPase activity	https://github.com/geneontology/go-ontology/issues/21626|https://github.com/geneontology/go-ontology/issues/20877			This term was obsoleted because it represents a molecular function.	GO:0140661	krc	2017-07-05T21:36:47Z		True	GO:1904622			biological_process											owl:Class	
GO:0006146	biolink:NamedThing	adenine catabolic process	The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.	got7fsn_ti	adenine catabolism|adenine breakdown|adenine degradation													biological_process											owl:Class	
GO:1901631	biolink:NamedThing	positive regulation of presynaptic membrane organization	Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization.	got7fsn_ti	up-regulation of presynaptic membrane organisation|up regulation of presynaptic membrane organization|positive regulation of presynaptic membrane organisation|activation of presynaptic membrane organization|positive regulation of pre-synaptic membrane organization|up-regulation of presynaptic membrane organization|activation of presynaptic membrane organisation|up regulation of presynaptic membrane organisation|upregulation of presynaptic membrane organisation|upregulation of presynaptic membrane organization						ans	2012-11-15T11:40:40Z						biological_process											owl:Class	
GO:0110090	biolink:NamedThing	positive regulation of hippocampal neuron apoptotic process	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.	got7fsn_ti							kmv	2018-02-13T21:22:18Z						biological_process											owl:Class	
GO:0033494	biolink:NamedThing	ferulate metabolic process	The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.	got7fsn_ti	ferulate metabolism													biological_process											owl:Class	
GO:0051097	biolink:NamedThing	negative regulation of helicase activity	Any process that stops or reduces the activity of a helicase.	got7fsn_ti	downregulation of helicase activity|down regulation of helicase activity|inhibition of helicase activity|down-regulation of helicase activity													biological_process											owl:Class	
GO:1903632	biolink:NamedThing	positive regulation of aminoacyl-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of aminoacyl-tRNA ligase activity.	got7fsn_ti	activation of aminoacyl-tRNA synthetase auxiliary protein activity|activation of aminoacyl-tRNA synthetase activity|up-regulation of aminoacyl-tRNA synthetase activity|upregulation of aminoacyl-tRNA synthetase auxiliary protein activity|activation of aminoacyl-tRNA ligase activity|upregulation of aminoacyl-tRNA ligase activity|up-regulation of aminoacyl-tRNA ligase activity|up regulation of aminoacyl-tRNA synthetase auxiliary protein activity|up regulation of aminoacyl-tRNA synthetase activity|up regulation of aminoacyl-tRNA ligase activity|positive regulation of aminoacyl-tRNA synthetase auxiliary protein activity|upregulation of aminoacyl-tRNA synthetase activity|up-regulation of aminoacyl-tRNA synthetase auxiliary protein activity|positive regulation of aminoacyl-tRNA synthetase activity						sl	2014-11-20T00:22:20Z						biological_process											owl:Class	
GO:0034119	biolink:NamedThing	negative regulation of erythrocyte aggregation	Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.	got7fsn_ti	negative regulation of red blood cell aggregation|negative regulation of RBC aggregation													biological_process											owl:Class	
GO:0006742	biolink:NamedThing	NADP catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.	got7fsn_ti	reduced nicotinamide adenine dinucleotide phosphate catabolic process|reduced NADP catabolic process|nicotinamide adenine dinucleotide phosphate catabolism|NADP (reduced) catabolism|oxidized NADP catabolic process|reduced NADP catabolism|oxidized nicotinamide adenine dinucleotide phosphate catabolism|NADP (oxidized) catabolism|NADP breakdown|NADP (oxidized) catabolic process|NADP catabolism|NADPH catabolism|NADP (reduced) catabolic process|oxidized nicotinamide adenine dinucleotide phosphate catabolic process|reduced nicotinamide adenine dinucleotide phosphate catabolism|NADP degradation|nicotinamide adenine dinucleotide phosphate catabolic process|NADPH catabolic process|oxidized NADP catabolism													biological_process											owl:Class	
GO:0140471	biolink:NamedThing	positive regulation of transepithelial migration of symbiont in host	Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host.	got7fsn_ti	positive regulation of transmigration of symbiont in host	https://github.com/geneontology/go-ontology/issues/19601					pg	2020-06-11T15:32:38Z						biological_process											owl:Class	
GO:0033488	biolink:NamedThing	cholesterol biosynthetic process via 24,25-dihydrolanosterol	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.	got7fsn_ti	cholesterol biosynthesis via 24,25-dihydrolanosterol|cholesterol formation via 24,25-dihydrolanosterol|cholesterol anabolism via 24,25-dihydrolanosterol|cholesterol synthesis via 24,25-dihydrolanosterol											MetaCyc:PWY66-3		biological_process											owl:Class	
GO:0030817	biolink:NamedThing	obsolete regulation of cAMP biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	regulation of cAMP synthesis|regulation of cAMP formation|regulation of cyclic AMP biosynthetic process|regulation of adenosine 3',5'-cyclophosphate biosynthesis|regulation of adenosine 3',5'-cyclophosphate biosynthetic process|regulation of 3',5'-cAMP biosynthetic process|regulation of 3',5'-cAMP biosynthesis|regulation of 3',5' cAMP biosynthesis|regulation of 3',5' cAMP biosynthetic process|regulation of cAMP biosynthesis|regulation of cyclic AMP biosynthesis|regulation of cAMP anabolism	https://github.com/geneontology/go-ontology/issues/14718			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0031562	biolink:NamedThing	hyphal tip polarisome	Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.	got7fsn_ti														cellular_component											owl:Class	
GO:1901655	biolink:NamedThing	cellular response to ketone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.	got7fsn_ti							pr	2012-11-20T10:55:51Z						biological_process											owl:Class	
GO:0005528	biolink:NamedThing	FK506 binding	Binding to a 23-membered macrolide lactone FK506.	got7fsn_ti	FK506-sensitive peptidyl-prolyl cis-trans isomerase													molecular_function											owl:Class	
GO:0002651	biolink:NamedThing	positive regulation of tolerance induction to self antigen	Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.	got7fsn_ti	up-regulation of tolerance induction to self antigen|activation of tolerance induction to self antigen|stimulation of tolerance induction to self antigen|upregulation of tolerance induction to self antigen|up regulation of tolerance induction to self antigen													biological_process											owl:Class	
GO:1901624	biolink:NamedThing	negative regulation of lymphocyte chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.	got7fsn_ti	down-regulation of lymphocyte chemotaxis|downregulation of lymphocyte chemotaxis|inhibition of lymphocyte chemotaxis|down regulation of lymphocyte chemotaxis						tb	2012-11-13T23:03:28Z						biological_process											owl:Class	
GO:1901340	biolink:NamedThing	negative regulation of store-operated calcium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity.	got7fsn_ti	inhibition of store-operated calcium channel activity|down-regulation of store-operated calcium channel activity|down regulation of store-operated calcium channel activity|downregulation of store-operated calcium channel activity						pr	2012-09-03T14:24:21Z						biological_process											owl:Class	
GO:1903250	biolink:NamedThing	positive regulation of citrulline biosynthetic process	Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process.	got7fsn_ti	up regulation of citrulline biosynthetic process|activation of citrulline biosynthesis|activation of citrulline anabolism|up-regulation of citrulline biosynthetic process|up regulation of citrulline anabolism|upregulation of citrulline biosynthesis|up-regulation of citrulline anabolism|upregulation of citrulline biosynthetic process|up-regulation of citrulline biosynthesis|up regulation of citrulline formation|activation of citrulline synthesis|up-regulation of citrulline formation|up-regulation of citrulline synthesis|activation of citrulline formation|up regulation of citrulline biosynthesis|upregulation of citrulline anabolism|activation of citrulline biosynthetic process|positive regulation of citrulline anabolism|up regulation of citrulline synthesis|positive regulation of citrulline synthesis|upregulation of citrulline synthesis|positive regulation of citrulline formation|positive regulation of citrulline biosynthesis|upregulation of citrulline formation						rl	2014-08-04T15:24:52Z						biological_process											owl:Class	
GO:0019881	biolink:NamedThing	obsolete streptomycin susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	streptomycin susceptibility/resistance			GO:0046679	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:1902215	biolink:NamedThing	negative regulation of interleukin-4-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway.	got7fsn_ti	downregulation of IL-4-mediated signaling pathway|down-regulation of interleukin-4-mediated signaling pathway|downregulation of interleukin-4-mediated signaling pathway|down regulation of interleukin-4-mediated signaling pathway|down regulation of interleukin-4-mediated signalling pathway|down-regulation of IL-4-mediated signaling pathway|inhibition of interleukin-4-mediated signaling pathway|down-regulation of interleukin-4-mediated signalling pathway|downregulation of interleukin-4-mediated signalling pathway|inhibition of IL-4-mediated signaling pathway|negative regulation of interleukin-4-mediated signalling pathway|negative regulation of IL-4-mediated signaling pathway|down regulation of IL-4-mediated signaling pathway|inhibition of interleukin-4-mediated signalling pathway						lb	2013-06-12T12:53:14Z						biological_process											owl:Class	
GO:0038075	biolink:NamedThing	obsolete MAP kinase activity involved in innate immune response	OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to an innate immune response.	got7fsn_ti	MAPK activity involved in innate immune response	https://github.com/geneontology/go-ontology/issues/18000			This term was obsoleted because it should be represented as a GO-CAM model.		bf	2012-01-26T02:35:52Z		True				molecular_function											owl:Class	
GO:1904674	biolink:NamedThing	positive regulation of somatic stem cell population maintenance	Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance.	got7fsn_ti	up regulation of somatic stem cell population maintenance|activation of somatic stem cell population maintenance|upregulation of somatic stem cell population maintenance|up-regulation of somatic stem cell population maintenance						rph	2015-09-14T08:40:32Z						biological_process											owl:Class	
GO:0120186	biolink:NamedThing	negative regulation of protein localization to chromatin	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin.	got7fsn_ti	negative regulation of protein localisation to chromatin						krc	2018-07-14T00:19:32Z						biological_process											owl:Class	
GO:1901377	biolink:NamedThing	organic heteropentacyclic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound.	got7fsn_ti	organic heteropentacyclic compound catabolism|organic heteropentacyclic compound breakdown|organic heteropentacyclic compound degradation						bf	2012-09-28T12:51:51Z						biological_process											owl:Class	
GO:0062158	biolink:NamedThing	chloride:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out).	got7fsn_ti							dph	2019-09-24T19:26:32Z						molecular_function											owl:Class	
GO:0075075	biolink:NamedThing	obsolete modulation by host of symbiont adenylate cyclase activity	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0120213	biolink:NamedThing	regulation of histidine biosynthetic process	Any process that modulates the frequency, rate or extent of histidine biosynthetic process.	got7fsn_ti	regulation of histidine biosynthesis|regulation of histidine formation|regulation of histidine synthesis|regulation of histidine anabolism						krc	2019-06-27T20:55:42Z						biological_process											owl:Class	
GO:1901928	biolink:NamedThing	cadinene biosynthetic process	The chemical reactions and pathways resulting in the formation of cadinene.	got7fsn_ti	cadinene formation|cadinene synthesis|cadinene anabolism|cadinene biosynthesis						ms	2013-02-18T14:54:34Z						biological_process											owl:Class	
GO:0032388	biolink:NamedThing	positive regulation of intracellular transport	Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.	got7fsn_ti	stimulation of intracellular transport|activation of intracellular transport|up-regulation of intracellular transport|upregulation of intracellular transport|up regulation of intracellular transport													biological_process											owl:Class	
GO:2000197	biolink:NamedThing	regulation of ribonucleoprotein complex localization	Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization.	got7fsn_ti	regulation of cellular ribonucleoprotein complex localization|regulation of ribonucleoprotein complex localisation|regulation of establishment and maintenance of ribonucleoprotein complex localization|regulation of RNP localization						mah	2010-10-26T10:35:48Z						biological_process											owl:Class	
GO:1900982	biolink:NamedThing	positive regulation of phenazine biosynthetic process	Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process.	got7fsn_ti	positive regulation of dibenzopyrazine biosynthetic process|up-regulation of azophenylene biosynthetic process|upregulation of acridizine biosynthetic process|activation of acridizine biosynthesis|positive regulation of acridizine biosynthesis|up regulation of azophenylene biosynthetic process|up regulation of acridizine biosynthesis|positive regulation of dibenzo-p-diazine biosynthesis|up-regulation of acridizine biosynthesis|positive regulation of azophenylene biosynthesis|up regulation of acridizine biosynthetic process|upregulation of dibenzo-p-diazine biosynthetic process|activation of azophenylene biosynthetic process|positive regulation of dibenzo-p-diazine biosynthetic process|upregulation of azophenylene biosynthetic process|activation of acridizine biosynthetic process|up regulation of azophenylene biosynthesis|upregulation of dibenzopyrazine biosynthetic process|up regulation of dibenzopyrazine biosynthesis|up regulation of dibenzo-p-diazine biosynthesis|up-regulation of phenazine biosynthetic process|upregulation of phenazine biosynthetic process|up-regulation of azophenylene biosynthesis|up-regulation of dibenzopyrazine biosynthesis|up regulation of dibenzopyrazine biosynthetic process|up-regulation of dibenzo-p-diazine biosynthetic process|positive regulation of azophenylene biosynthetic process|positive regulation of acridizine biosynthetic process|activation of azophenylene biosynthesis|up-regulation of dibenzopyrazine biosynthetic process|activation of dibenzo-p-diazine biosynthesis|upregulation of dibenzo-p-diazine biosynthesis|activation of dibenzopyrazine biosynthesis|upregulation of azophenylene biosynthesis|up-regulation of dibenzo-p-diazine biosynthesis|upregulation of dibenzopyrazine biosynthesis|up-regulation of acridizine biosynthetic process|activation of dibenzopyrazine biosynthetic process|upregulation of acridizine biosynthesis|activation of dibenzo-p-diazine biosynthetic process|up regulation of dibenzo-p-diazine biosynthetic process|activation of phenazine biosynthetic process|positive regulation of dibenzopyrazine biosynthesis|up regulation of phenazine biosynthetic process						tt	2012-06-14T04:05:10Z						biological_process											owl:Class	
GO:0033501	biolink:NamedThing	galactose homeostasis	A homeostatic process involved in the maintenance of an internal steady state of galactose within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:1900641	biolink:NamedThing	negative regulation of austinol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process.	got7fsn_ti	downregulation of austinol anabolism|negative regulation of austinol biosynthesis|inhibition of austinol biosynthetic process|negative regulation of austinol formation|downregulation of austinol biosynthesis|down regulation of austinol synthesis|down regulation of austinol anabolism|down-regulation of austinol formation|downregulation of austinol biosynthetic process|inhibition of austinol formation|down-regulation of austinol anabolism|downregulation of austinol synthesis|down-regulation of austinol synthesis|down-regulation of austinol biosynthesis|down-regulation of austinol biosynthetic process|inhibition of austinol synthesis|down regulation of austinol biosynthesis|inhibition of austinol biosynthesis|negative regulation of austinol anabolism|down regulation of austinol biosynthetic process|downregulation of austinol formation|negative regulation of austinol synthesis|down regulation of austinol formation|inhibition of austinol anabolism						di	2012-05-22T03:57:59Z						biological_process											owl:Class	
GO:0045887	biolink:NamedThing	positive regulation of synaptic assembly at neuromuscular junction	Any process that activates or increases the frequency, rate or extent of synaptic assembly at neuromuscular junction.	got7fsn_ti	up-regulation of synaptic growth at neuromuscular junction|activation of synaptic growth at neuromuscular junction|stimulation of synaptic growth at neuromuscular junction|upregulation of synaptic growth at neuromuscular junction|up regulation of synaptic growth at neuromuscular junction|positive regulation of synaptic growth at neuromuscular junction													biological_process											owl:Class	
GO:1905944	biolink:NamedThing	positive regulation of formation of growth cone in injured axon	Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon.	got7fsn_ti	activation of formation of growth cone in injured axon|upregulation of formation of growth cone in injured axon|up regulation of formation of growth cone in injured axon|up-regulation of formation of growth cone in injured axon						rz	2017-02-13T09:09:21Z						biological_process											owl:Class	
GO:0045649	biolink:NamedThing	regulation of macrophage differentiation	Any process that modulates the frequency, rate or extent of macrophage differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1903745	biolink:NamedThing	negative regulation of pharyngeal pumping	Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping.	got7fsn_ti	down-regulation of pumping behavior|downregulation of pumping behavior|inhibition of pharyngeal pumping|downregulation of pharyngeal pumping|down regulation of pharyngeal pumping|down-regulation of pharyngeal pumping|down regulation of pumping behavior|inhibition of pumping behavior|negative regulation of pumping behavior						kmv	2014-12-12T17:10:59Z						biological_process											owl:Class	
GO:0001169	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase I CORE element sequence-specific binding	OBSOLETE. Binding to CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I.	got7fsn_ti	RNA polymerase I core promoter sequence-specific DNA binding transcription factor|RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/15787			This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2011-02-03T04:10:42Z		True				molecular_function											owl:Class	
GO:0002581	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.	got7fsn_ti	inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II													biological_process											owl:Class	
GO:2000723	biolink:NamedThing	negative regulation of cardiac vascular smooth muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.	got7fsn_ti	negative regulation of heart vascular smooth muscle cell differentiation						vk	2011-06-08T08:48:01Z						biological_process											owl:Class	
GO:0034648	biolink:NamedThing	obsolete histone demethylase activity (H3-dimethyl-K4 specific)	OBSOLETE. Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein.	got7fsn_ti	histone demethylase activity (H3-K4-me2 specific)	https://github.com/geneontology/go-ontology/issues/21089			This term was obsoleted to align with RHEA and EC: this is a sub-reaction both in RHEA:60208 and EC:1.14.11.67.	GO:0140682|GO:0034647				True				molecular_function											owl:Class	
GO:0045613	biolink:NamedThing	regulation of plasmatocyte differentiation	Any process that modulates the frequency, rate or extent of plasmatocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1900912	biolink:NamedThing	negative regulation of olefin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process.	got7fsn_ti	inhibition of olefin biosynthesis|down regulation of olefin biosynthetic process|downregulation of olefin biosynthesis|inhibition of olefin biosynthetic process|down regulation of olefin anabolism|downregulation of olefin biosynthetic process|down-regulation of olefin anabolism|inhibition of olefin synthesis|downregulation of olefin formation|down-regulation of olefin formation|down-regulation of olefin biosynthetic process|down-regulation of olefin synthesis|inhibition of olefin formation|negative regulation of olefin formation|down regulation of olefin biosynthesis|downregulation of olefin synthesis|down-regulation of olefin biosynthesis|down regulation of olefin formation|negative regulation of olefin biosynthesis|negative regulation of olefin synthesis|inhibition of olefin anabolism|downregulation of olefin anabolism|negative regulation of olefin anabolism|down regulation of olefin synthesis						tt	2012-06-13T04:20:30Z						biological_process											owl:Class	
GO:1904585	biolink:NamedThing	response to putrescine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.	got7fsn_ti	response to tetramethylenediamine|response to 1,4-Diaminobutane|response to 1,4-Butanediamine						sl	2015-08-20T14:35:39Z						biological_process											owl:Class	
GO:0045370	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905399	biolink:NamedThing	regulation of activated CD4-positive, alpha-beta T cell apoptotic process	Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.	got7fsn_ti	regulation of activated CD4-positive, alpha-beta T cell apoptosis|regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|regulation of activated CD4-positive, alpha-beta T-cell apoptosis|regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process						pga	2016-08-25T09:09:46Z						biological_process											owl:Class	
GO:1905171	biolink:NamedThing	positive regulation of protein localization to phagocytic vesicle	Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle.	got7fsn_ti	activation of protein localization in phagocytic vesicle|upregulation of protein recruitment to phagosome|up-regulation of protein localization in phagocytic vesicle|activation of protein localization to phagocytic vesicle|up regulation of protein localization in phagocytic vesicle|up regulation of protein localisation in phagocytic vesicle|activation of protein localisation to phagocytic vesicle|up regulation of protein localization to phagocytic vesicle|positive regulation of protein localisation to phagosome|upregulation of protein localization in phagocytic vesicle|up-regulation of protein localization to phagocytic vesicle|positive regulation of protein localisation to phagocytic vesicle|upregulation of protein localisation to phagosome|up regulation of protein localisation to phagocytic vesicle|upregulation of protein localisation to phagocytic vesicle|up-regulation of protein localisation to phagosome|positive regulation of protein localization in phagocytic vesicle|activation of protein recruitment to phagosome|up-regulation of protein recruitment to phagosome|up regulation of protein recruitment to phagosome|activation of protein localisation to phagosome|up-regulation of protein localisation in phagocytic vesicle|positive regulation of protein recruitment to phagosome|up regulation of protein localisation to phagosome|upregulation of protein localisation in phagocytic vesicle|activation of protein localisation in phagocytic vesicle|upregulation of protein localization to phagocytic vesicle|up-regulation of protein localisation to phagocytic vesicle|positive regulation of protein localisation in phagocytic vesicle						bf	2016-05-02T18:38:30Z						biological_process											owl:Class	
GO:0003815	biolink:NamedThing	obsolete complement component C1r activity	OBSOLETE. Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42).	got7fsn_ti	complement subcomponent C1r|C1r esterase activity|activated complement C1r|complement component C1r activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1900781	biolink:NamedThing	fumiquinazoline C biosynthetic process	The chemical reactions and pathways resulting in the formation of fumiquinazoline C.	got7fsn_ti	fumiquinazoline C anabolism|fumiquinazoline C formation|fumiquinazoline C biosynthesis|fumiquinazoline C synthesis						di	2012-06-04T09:30:58Z						biological_process											owl:Class	
GO:1900688	biolink:NamedThing	positive regulation of gerfelin biosynthetic process	Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process.	got7fsn_ti	activation of gerfelin formation|positive regulation of gerfelin formation|up-regulation of gerfelin formation|up regulation of gerfelin formation|activation of gerfelin biosynthesis|positive regulation of gerfelin anabolism|upregulation of gerfelin formation|up regulation of gerfelin biosynthetic process|up regulation of gerfelin anabolism|up-regulation of gerfelin biosynthesis|positive regulation of gerfelin biosynthesis|activation of gerfelin biosynthetic process|activation of gerfelin synthesis|activation of gerfelin anabolism|up-regulation of gerfelin synthesis|upregulation of gerfelin biosynthetic process|upregulation of gerfelin biosynthesis|up regulation of gerfelin biosynthesis|upregulation of gerfelin synthesis|positive regulation of gerfelin synthesis|up-regulation of gerfelin biosynthetic process|upregulation of gerfelin anabolism|up regulation of gerfelin synthesis|up-regulation of gerfelin anabolism						di	2012-05-22T04:50:12Z						biological_process											owl:Class	
GO:1900684	biolink:NamedThing	negative regulation of fumonisin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process.	got7fsn_ti	negative regulation of fumonisin formation|down-regulation of fumonisin formation|inhibition of fumonisin biosynthesis|negative regulation of fumonisin synthesis|downregulation of fumonisin synthesis|inhibition of fumonisin formation|down regulation of fumonisin biosynthesis|downregulation of fumonisin biosynthesis|down regulation of fumonisin synthesis|inhibition of fumonisin biosynthetic process|downregulation of fumonisin formation|down regulation of fumonisin anabolism|inhibition of fumonisin anabolism|down regulation of fumonisin formation|down-regulation of fumonisin synthesis|negative regulation of fumonisin biosynthesis|negative regulation of fumonisin anabolism|inhibition of fumonisin synthesis|down-regulation of fumonisin biosynthesis|downregulation of fumonisin anabolism|downregulation of fumonisin biosynthetic process|down regulation of fumonisin biosynthetic process|down-regulation of fumonisin biosynthetic process|down-regulation of fumonisin anabolism						di	2012-05-22T04:29:59Z						biological_process											owl:Class	
GO:1900179	biolink:NamedThing	positive regulation of aflatoxin biosynthetic process	Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process.	got7fsn_ti	up regulation of aflatoxin anabolism|up regulation of aflatoxin synthesis|up regulation of aflatoxin biosynthetic process|upregulation of aflatoxin anabolism|activation of aflatoxin biosynthesis|up-regulation of aflatoxin anabolism|upregulation of aflatoxin synthesis|upregulation of aflatoxin biosynthesis|positive regulation of aflatoxin synthesis|activation of aflatoxin biosynthetic process|activation of aflatoxin formation|up-regulation of aflatoxin formation|up-regulation of aflatoxin synthesis|positive regulation of aflatoxin anabolism|upregulation of aflatoxin biosynthetic process|activation of aflatoxin synthesis|up regulation of aflatoxin biosynthesis|positive regulation of aflatoxin formation|positive regulation of aflatoxin biosynthesis|up regulation of aflatoxin formation|upregulation of aflatoxin formation|up-regulation of aflatoxin biosynthetic process|activation of aflatoxin anabolism|up-regulation of aflatoxin biosynthesis						di	2012-03-09T11:23:46Z						biological_process											owl:Class	
GO:1902548	biolink:NamedThing	negative regulation of cellular response to vascular endothelial growth factor stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.	got7fsn_ti	downregulation of cellular response to VEGFA|downregulation of cellular response to vascular endothelial growth factor stimulus|negative regulation of cellular response to VEGF|negative regulation of cellular response to VEGFA|down-regulation of cellular response to VEGF|inhibition of cellular response to VEGFB|inhibition of cellular response to VEGF|down-regulation of cellular response to VEGFA|down regulation of cellular response to VEGFB|inhibition of cellular response to vascular endothelial growth factor|down-regulation of cellular response to vascular endothelial growth factor|down-regulation of cellular response to VEGFB|downregulation of cellular response to VEGF|down regulation of cellular response to VEGF|negative regulation of cellular response to vascular endothelial growth factor|down regulation of cellular response to vascular endothelial growth factor stimulus|inhibition of cellular response to vascular endothelial growth factor stimulus|down-regulation of cellular response to vascular endothelial growth factor stimulus|down regulation of cellular response to vascular endothelial growth factor|inhibition of cellular response to VEGFA|negative regulation of cellular response to VEGFB|downregulation of cellular response to vascular endothelial growth factor|down regulation of cellular response to VEGFA|downregulation of cellular response to VEGFB				ADAMTS12 (UniProt ID P58397) in human in PMID:17895370 inhibits the formation of VEGF-induced tubular structures in BAE-1 cells (endothelial cell line).		rl	2013-12-04T15:15:03Z						biological_process											owl:Class	
GO:0017019	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050855	biolink:NamedThing	regulation of B cell receptor signaling pathway	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.	got7fsn_ti	regulation of B-cell receptor signaling pathway|regulation of B lymphocyte receptor signaling pathway|regulation of B-lymphocyte receptor signalling pathway|regulation of B-lymphocyte receptor signaling pathway|regulation of B cell receptor signalling pathway|regulation of B-cell receptor signalling pathway|regulation of B lymphocyte receptor signalling pathway													biological_process											owl:Class	
UBERON:0000947	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070509	biolink:NamedThing	calcium ion import	The directed movement of calcium ions into a cell or organelle.	got7fsn_ti	transmembrane calcium influx|calcium ion uptake													biological_process											owl:Class	
GO:0050543	biolink:NamedThing	icosatetraenoic acid binding	Binding to icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule.	got7fsn_ti	eicosatetraenoic acid binding													molecular_function											owl:Class	
GO:1900873	biolink:NamedThing	pentadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of pentadec-1-ene.	got7fsn_ti	pentadec-1-ene synthesis|pentadec-1-ene biosynthesis|pentadec-1-ene anabolism|pentadec-1-ene formation						tt	2012-06-13T01:45:45Z						biological_process											owl:Class	
GO:0002594	biolink:NamedThing	positive regulation of antigen processing and presentation via MHC class Ib	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.	got7fsn_ti	up-regulation of antigen processing and presentation via MHC class Ib|upregulation of antigen processing and presentation via MHC class Ib|up regulation of antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation via MHC class Ib|activation of antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:1905362	biolink:NamedThing	negative regulation of endosomal vesicle fusion	Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion.	got7fsn_ti	down-regulation of endosomal vesicle fusion|negative regulation of endosome vesicle fusion|downregulation of endosomal vesicle fusion|inhibition of endosome vesicle fusion|down regulation of endosomal vesicle fusion|downregulation of endosome vesicle fusion|down-regulation of endosome vesicle fusion|down regulation of endosome vesicle fusion|inhibition of endosomal vesicle fusion						bc	2016-08-16T11:40:44Z						biological_process											owl:Class	
GO:0030489	biolink:NamedThing	obsolete processing of 27S pre-rRNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	processing of 27S pre-rRNA				This term was made obsolete because it was not defined and did not correspond to the production of a single specific mature rRNA product.					True				biological_process											owl:Class	
GO:0097153	biolink:NamedThing	cysteine-type endopeptidase activity involved in apoptotic process	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.	got7fsn_ti	caspase activity|metacaspase activity						pr	2011-09-09T10:21:56Z				Reactome:R-HSA-6800797		molecular_function											owl:Class	
GO:1904814	biolink:NamedThing	regulation of protein localization to chromosome, telomeric region	Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region.	got7fsn_ti	regulation of protein localization to telomere|regulation of protein localisation to chromosome, telomeric region						nc	2015-11-16T12:18:43Z						biological_process											owl:Class	
GO:0061869	biolink:NamedThing	regulation of hepatic stellate cell migration	Any process that modulates the frequency, rate or extent of hepatic stellate cell migration.	got7fsn_ti							dph	2017-05-01T13:04:20Z						biological_process											owl:Class	
GO:1900911	biolink:NamedThing	regulation of olefin biosynthetic process	Any process that modulates the frequency, rate or extent of olefin biosynthetic process.	got7fsn_ti	regulation of olefin biosynthesis|regulation of olefin synthesis|regulation of olefin formation|regulation of olefin anabolism						tt	2012-06-13T04:20:08Z						biological_process											owl:Class	
GO:1905165	biolink:NamedThing	regulation of lysosomal protein catabolic process	Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process.	got7fsn_ti	regulation of cellular protein catabolism in lysosome|regulation of cellular protein catabolic process in lysosome|regulation of lysosomal proteolysis|regulation of proteolysis within lysosome|regulation of lysosomal protein degradation|regulation of cellular protein degradation in lysosome|regulation of cellular protein breakdown in lysosome|regulation of lysosomal protein catabolism						bf	2016-04-26T12:10:01Z						biological_process											owl:Class	
GO:0034252	biolink:NamedThing	negative regulation of cellular amide catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.	got7fsn_ti	negative regulation of amide catabolism|negative regulation of amide degradation|negative regulation of amide breakdown													biological_process											owl:Class	
GO:0048517	biolink:NamedThing	obsolete positive regulation of trichome initiation (sensu Magnoliophyta)	OBSOLETE. Any process that activates or increases the frequency, rate or extent of trichome initiation; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398).	got7fsn_ti	positive regulation of trichome initiation (sensu Magnoliophyta)				This term was made obsolete because more appropriate terms were created.	GO:0048629				True				biological_process											owl:Class	
GO:1900035	biolink:NamedThing	negative regulation of cellular response to heat	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat.	got7fsn_ti	downregulation of cellular response to heat|down-regulation of cellular response to heat stress|inhibition of cellular response to heat stress|down-regulation of cellular response to heat|negative regulation of cellular response to heat stress|down regulation of cellular response to heat|down regulation of cellular response to heat stress|downregulation of cellular response to heat stress|inhibition of cellular response to heat						yaf	2012-01-17T09:27:44Z						biological_process											owl:Class	
GO:0006045	biolink:NamedThing	N-acetylglucosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.	got7fsn_ti	N-acetylglucosamine synthesis|N-acetylglucosamine biosynthesis|N-acetylglucosamine anabolism|N-acetylglucosamine formation													biological_process											owl:Class	
GO:1904200	biolink:NamedThing	iodide transmembrane transport	The process in which iodide is transported across a membrane.	got7fsn_ti							sl	2015-05-08T15:17:19Z						biological_process											owl:Class	
GO:0070779	biolink:NamedThing	D-aspartate import across plasma membrane	The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.	got7fsn_ti	D-aspartate import|D-aspartate import into cell|D-aspartate uptake						mah	2009-07-02T01:57:00Z			GO:0140016			biological_process											owl:Class	
GO:0032914	biolink:NamedThing	positive regulation of transforming growth factor beta1 production	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.	got7fsn_ti	upregulation of transforming growth factor-beta1 production|activation of transforming growth factor-beta1 production|stimulation of transforming growth factor-beta1 production|up-regulation of transforming growth factor-beta1 production|up regulation of transforming growth factor-beta1 production|positive regulation of TGFB1 production|positive regulation of TGF-B1 production													biological_process											owl:Class	
GO:1904141	biolink:NamedThing	positive regulation of microglial cell migration	Any process that activates or increases the frequency, rate or extent of microglial cell migration.	got7fsn_ti	upregulation of microglial cell migration|up-regulation of microglial cell migration|activation of microglial cell migration|up regulation of microglial cell migration						nc	2015-04-13T09:07:11Z						biological_process											owl:Class	
GO:0046833	biolink:NamedThing	positive regulation of RNA export from nucleus	Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm.	got7fsn_ti	stimulation of RNA export from nucleus|positive regulation of RNA transport from nucleus to cytoplasm|up regulation of RNA export from nucleus|positive regulation of RNA export from cell nucleus|up-regulation of RNA export from nucleus|activation of RNA export from nucleus|positive regulation of RNA export out of nucleus|upregulation of RNA export from nucleus|positive regulation of RNA-nucleus export													biological_process											owl:Class	
GO:0051917	biolink:NamedThing	regulation of fibrinolysis	Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.	got7fsn_ti														biological_process											owl:Class	
GO:0009350	biolink:NamedThing	ethanolamine ammonia-lyase complex	An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia.	got7fsn_ti														cellular_component											owl:Class	
GO:0048214	biolink:NamedThing	regulation of Golgi vesicle fusion to target membrane	Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane.	got7fsn_ti					Note that GTP-binding Rab proteins serve as regulators of vesicle targeting and fusion.									biological_process											owl:Class	
GO:0046400	biolink:NamedThing	keto-3-deoxy-D-manno-octulosonic acid metabolic process	The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.	got7fsn_ti	KDO metabolic process|keto-3-deoxy-D-manno-octulosonic acid metabolism|KDO metabolism|ketodeoxyoctanoate metabolic process													biological_process											owl:Class	
GO:0051354	biolink:NamedThing	negative regulation of oxidoreductase activity	Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.	got7fsn_ti	oxidoreductase inhibitor|downregulation of oxidoreductase activity|down regulation of oxidoreductase activity|inhibition of oxidoreductase activity|down-regulation of oxidoreductase activity													biological_process											owl:Class	
GO:1905704	biolink:NamedThing	positive regulation of inhibitory synapse assembly	Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly.	got7fsn_ti	up regulation of inhibitory synapse formation|upregulation of inhibitory synapse formation|up regulation of inhibitory synapse assembly|activation of inhibitory synapse assembly|up-regulation of inhibitory synapse formation|positive regulation of inhibitory synapse formation|upregulation of inhibitory synapse assembly|up-regulation of inhibitory synapse assembly|activation of inhibitory synapse formation						tb	2016-11-16T18:55:49Z						biological_process											owl:Class	
GO:0051549	biolink:NamedThing	positive regulation of keratinocyte migration	Any process that activates or increases the frequency, rate or extent of keratinocyte migration.	got7fsn_ti	stimulation of keratinocyte migration|up-regulation of keratinocyte migration|up regulation of keratinocyte migration|activation of keratinocyte migration|upregulation of keratinocyte migration													biological_process											owl:Class	
GO:0007363	biolink:NamedThing	obsolete positive regulation of terminal gap gene transcription	OBSOLETE. The activation of genes encoding transcription factors at the anterior and posterior ends of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila tailless and huckebein genes.	got7fsn_ti	upregulation of terminal gap gene transcription|activation of terminal gap gene|activation of terminal gap gene transcription|stimulation of terminal gap gene transcription|up-regulation of terminal gap gene transcription|up regulation of terminal gap gene transcription				This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0042837	biolink:NamedThing	D-glucarate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate.	got7fsn_ti	D-glucarate synthesis|D-glucarate anabolism|saccharate biosynthesis|saccharate biosynthetic process|D-glucarate formation|D-glucarate biosynthesis													biological_process											owl:Class	
GO:0043415	biolink:NamedThing	positive regulation of skeletal muscle tissue regeneration	Any process that activates or increase the rate of skeletal muscle regeneration.	got7fsn_ti	up-regulation of skeletal muscle regeneration|up regulation of skeletal muscle regeneration|activation of skeletal muscle regeneration|stimulation of skeletal muscle regeneration|upregulation of skeletal muscle regeneration													biological_process											owl:Class	
GO:0001900	biolink:NamedThing	positive regulation of cytolysis by symbiont of host cells	Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by symbiont of cytolysis of host cells|stimulation by symbiont of cytolysis of host cells|up regulation by symbiont of cytolysis of host cells|upregulation by symbiont of cytolysis of host cells|up-regulation by symbiont of cytolysis of host cells|positive regulation by symbiont of cytolysis of host cells													biological_process											owl:Class	
GO:0051927	biolink:NamedThing	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel.	got7fsn_ti	down-regulation of calcium ion transport via voltage gated calcium channel|downregulation of calcium ion transport via voltage gated calcium channel|down regulation of calcium ion transport via voltage gated calcium channel|negative regulation of calcium transport via voltage gated calcium channel|negative regulation of calcium ion transport via voltage-gated calcium channel activity|inhibition of calcium ion transport via voltage gated calcium channel				This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0005245				True				biological_process											owl:Class	
GO:0032236	biolink:NamedThing	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.	got7fsn_ti	positive regulation of calcium transport via store-operated calcium channel|positive regulation of calcium ion transport via store-operated calcium channel activity|stimulation of calcium ion transport via store-operated calcium channel|positive regulation of store-operated calcium channel activity|up regulation of calcium ion transport via store-operated calcium channel|activation of calcium ion transport via store-operated calcium channel|upregulation of calcium ion transport via store-operated calcium channel|up-regulation of calcium ion transport via store-operated calcium channel				This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0015279				True				biological_process											owl:Class	
GO:1905188	biolink:NamedThing	positive regulation of metaphase/anaphase transition of meiosis I	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I.	got7fsn_ti	positive regulation of meiosis I metaphase/anaphase transition						vw	2016-05-10T16:32:19Z						biological_process											owl:Class	
GO:1905230	biolink:NamedThing	response to borneol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.	got7fsn_ti							sl	2016-06-07T17:18:36Z						biological_process											owl:Class	
GO:1900051	biolink:NamedThing	positive regulation of histone exchange	Any process that activates or increases the frequency, rate or extent of histone exchange.	got7fsn_ti	activation of histone exchange|upregulation of histone replacement|activation of histone replacement|upregulation of histone exchange|positive regulation of histone chaperone|up regulation of histone chaperone|up-regulation of histone chaperone|up regulation of histone exchange|up-regulation of histone exchange|activation of histone chaperone|upregulation of histone chaperone|up-regulation of histone replacement|up regulation of histone replacement|positive regulation of histone replacement						se	2012-01-19T10:59:12Z						biological_process											owl:Class	
GO:0019245	biolink:NamedThing	D(-)-lactate biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate.	got7fsn_ti	D(-)-lactate synthesis from pyruvate|D(-)-lactate anabolism from pyruvate|D(-)-lactate formation from pyruvate													biological_process											owl:Class	
GO:1903338	biolink:NamedThing	regulation of cell wall organization or biogenesis	Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis.	got7fsn_ti	regulation of cell wall organization or biogenesis at cellular level|regulation of cellular cell wall organization or biogenesis|regulation of cell wall organisation or biogenesis|regulation of cellular cell wall organisation or biogenesis						vw	2014-08-18T13:20:50Z						biological_process											owl:Class	
GO:1901830	biolink:NamedThing	zeaxanthin bis(beta-D-glucoside) biosynthetic process	The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside).	got7fsn_ti	zeaxanthin diglucoside synthesis|zeaxanthin diglucoside biosynthesis|zeaxanthin diglucoside anabolism|zeaxanthin bis(beta-D-glucoside) synthesis|zeaxanthin bis(beta-D-glucoside) anabolism|zeaxanthin bis(beta-D-glucoside) biosynthesis|zeaxanthin bis(beta-D-glucoside) formation|zeaxanthin diglucoside formation						yaf	2013-01-22T12:32:10Z						biological_process											owl:Class	
GO:1900002	biolink:NamedThing	positive regulation of anthocyanin catabolic process	Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process.	got7fsn_ti	up regulation of anthocyanin degradation|positive regulation of anthocyanin degradation|up regulation of anthocyanin catabolism|positive regulation of anthocyanin breakdown|up regulation of anthocyanin breakdown|positive regulation of anthocyanin catabolism|up regulation of anthocyanin catabolic process						tb	2011-12-20T07:12:15Z						biological_process											owl:Class	
GO:0033187	biolink:NamedThing	obsolete inositol hexakisphosphate 4-kinase or 6-kinase activity	OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.	got7fsn_ti	inositol hexakisphosphate 4-kinase or 6-kinase activity				This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0000830|GO:0000831				True				molecular_function											owl:Class	
GO:0071301	biolink:NamedThing	cellular response to vitamin B1	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.	got7fsn_ti	cellular response to thiamin|cellular response to thiamine						mah	2009-12-10T04:32:09Z						biological_process											owl:Class	
GO:1901367	biolink:NamedThing	response to L-cysteine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus.	got7fsn_ti							bf	2012-09-18T13:49:42Z						biological_process											owl:Class	
GO:0045816	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009388	biolink:NamedThing	obsolete antisense RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	antisense RNA				This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0010543	biolink:NamedThing	regulation of platelet activation	Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.	got7fsn_ti														biological_process											owl:Class	
GO:0045796	biolink:NamedThing	negative regulation of intestinal cholesterol absorption	Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.	got7fsn_ti	inhibition of cholesterol absorption|down-regulation of cholesterol absorption|down regulation of cholesterol absorption|downregulation of cholesterol absorption													biological_process											owl:Class	
GO:1905462	biolink:NamedThing	regulation of DNA duplex unwinding	Any process that modulates the frequency, rate or extent of DNA duplex unwinding.	got7fsn_ti	regulation of DNA unwinding|regulation of duplex DNA melting						ans	2016-09-19T11:58:41Z						biological_process											owl:Class	
GO:1901140	biolink:NamedThing	p-coumaryl alcohol transport	The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	4-hydroxycinnamyl alcohol transport						tb	2012-07-12T09:46:16Z						biological_process											owl:Class	
GO:1990704	biolink:NamedThing	integral component of Golgi trans cisterna membrane	The component of the Golgi trans membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral component of trans-Golgi cisterna membrane						bhm	2015-03-16T16:08:07Z						cellular_component											owl:Class	
GO:0035463	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to determination of organismal asymmetry with respect to the left and right halves.	got7fsn_ti	transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry|TGFbeta receptor signalling pathway involved in determination of left/right asymmetry|TGF-beta receptor signalling pathway involved in determination of left/right asymmetry|TGF-beta receptor signaling pathway involved in determination of left/right asymmetry|TGFbeta receptor signaling pathway involved in determination of left/right asymmetry						bf	2010-04-19T01:19:20Z						biological_process											owl:Class	
GO:1900293	biolink:NamedThing	positive regulation of galactotriose transport	Any process that activates or increases the frequency, rate or extent of galactotriose transport.	got7fsn_ti	upregulation of galactotriose transport|up-regulation of galactotriose transport|up regulation of galactotriose transport|activation of galactotriose transport						tt	2012-04-05T07:26:28Z						biological_process											owl:Class	
GO:1900753	biolink:NamedThing	doxorubicin transport	The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	(8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione transport|Adriamycin transport|doxorubicinum transport|14-hydroxydaunomycin transport|14-hydroxydaunorubicine transport|(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport|doxorubicine transport|(1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport						jl	2012-05-29T02:50:43Z						biological_process											owl:Class	
GO:1904040	biolink:NamedThing	positive regulation of iron export across plasma membrane	Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	activation of iron(2+) export|positive regulation of ferrous iron export|up regulation of iron(2+) export|up regulation of ferrous iron export|positive regulation of iron(2+) export|upregulation of iron(2+) export|up-regulation of ferrous iron export|activation of ferrous iron export|upregulation of ferrous iron export|up-regulation of iron(2+) export						kom	2015-03-16T15:36:49Z						biological_process											owl:Class	
GO:0008567	biolink:NamedThing	obsolete dynein ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by dynein that provides the energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome.	got7fsn_ti	dynein ATPase activity				This term was made obsolete because it represents a class of gene products, and its definition incorporates process information.	GO:0003777|GO:0007018				True				molecular_function											owl:Class	
GO:0015617	biolink:NamedThing	obsolete pilin/fimbrilin exporter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	pilin/fimbrilin exporter activity				This term was made obsolete because it represents a gene product.	GO:0015462				True				molecular_function											owl:Class	
GO:1902488	biolink:NamedThing	cholangiocyte apoptotic process	Any apoptotic process in a cholangiocyte.	got7fsn_ti	epithelial cell of bile duct apoptosis|cholangiocyte apoptosis|epithelial cell of bile duct apoptotic process						cls	2013-11-12T15:30:08Z						biological_process											owl:Class	
GO:0036010	biolink:NamedThing	protein localization to endosome	A process in which a protein is transported to, or maintained in, a location within an endosome.	got7fsn_ti	protein localisation in endosome|protein localization in endosome						bf	2011-10-06T02:42:18Z						biological_process											owl:Class	
GO:2000616	biolink:NamedThing	negative regulation of histone H3-K9 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation.	got7fsn_ti	negative regulation of histone H3K9 acetylation|negative regulation of histone H3 acetylation at K9						vk	2011-04-18T03:16:04Z						biological_process											owl:Class	
GO:0046311	biolink:NamedThing	prenylcysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.	got7fsn_ti	prenylcysteine anabolism|prenylcysteine formation|prenylcysteine synthesis|prenylcysteine biosynthesis													biological_process											owl:Class	
GO:1903601	biolink:NamedThing	thermospermine metabolic process	The chemical reactions and pathways involving thermospermine.	got7fsn_ti	thermospermine metabolism						tb	2014-11-12T18:47:55Z						biological_process											owl:Class	
GO:1900142	biolink:NamedThing	negative regulation of oligodendrocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process.	got7fsn_ti	down-regulation of oligodendrocyte apoptosis|down regulation of oligodendrocyte apoptosis|inhibition of oligodendrocyte apoptosis|inhibition of oligodendrocyte apoptotic process|down-regulation of oligodendrocyte apoptotic process|downregulation of oligodendrocyte apoptosis|downregulation of oligodendrocyte apoptotic process|negative regulation of oligodendrocyte apoptosis|down regulation of oligodendrocyte apoptotic process						yaf	2012-03-06T10:22:50Z						biological_process											owl:Class	
GO:1904042	biolink:NamedThing	negative regulation of cystathionine beta-synthase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity.	got7fsn_ti	down regulation of serine sulfhydrylase activity|negative regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|negative regulation of L-serine hydro-lyase (adding homocysteine)|inhibition of beta-thionase activity|negative regulation of methylcysteine synthase activity|downregulation of beta-thionase activity|down-regulation of cystathionine beta-synthase activity|down regulation of L-serine hydro-lyase (adding homocysteine)|downregulation of methylcysteine synthase activity|inhibition of cystathionine beta-synthase activity|down-regulation of serine sulfhydrase activity|down regulation of serine sulfhydrase activity|negative regulation of beta-thionase activity|downregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down regulation of methylcysteine synthase activity|downregulation of cystathionine beta-synthase activity|inhibition of methylcysteine synthase activity|down regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|inhibition of serine sulfhydrase activity|down-regulation of L-serine hydro-lyase (adding homocysteine)|inhibition of L-serine hydro-lyase (adding homocysteine)|negative regulation of serine sulfhydrylase activity|down regulation of beta-thionase activity|inhibition of serine sulfhydrylase activity|down regulation of cystathionine beta-synthase activity|inhibition of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|downregulation of L-serine hydro-lyase (adding homocysteine)|down-regulation of beta-thionase activity|negative regulation of serine sulfhydrase activity|down-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down-regulation of serine sulfhydrylase activity|downregulation of serine sulfhydrase activity|down-regulation of methylcysteine synthase activity|downregulation of serine sulfhydrylase activity						hal	2015-03-16T15:52:47Z						biological_process											owl:Class	
GO:0140042	biolink:NamedThing	lipid droplet formation	A process that results in the assembly, arrangement of constituent parts of a lipid droplet.	got7fsn_ti	lipid body formation|adiposome formation|lipid particle formation						pg	2017-06-19T09:18:43Z						biological_process											owl:Class	
GO:0003809	biolink:NamedThing	obsolete thrombin activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Gly; activates fibrinogen to fibrin and releases fibrinopeptide A and B.	got7fsn_ti	thrombase activity|beta-thrombin|gamma-thrombin|fibrinogenase activity|activated blood-coagulation factor II|E thrombin|blood-coagulation factor IIa|thrombofort|factor IIa|tropostasin|thrombin activity|topical|thrombin-C			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1902167	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.	got7fsn_ti	upregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|activation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|activation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator						lb	2013-05-22T12:45:20Z						biological_process											owl:Class	
GO:1902768	biolink:NamedThing	isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate	The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate.	got7fsn_ti	isoprenoid synthesis via 1-deoxy-D-xylulose 5-phosphate|isoprenoid formation via 1-deoxy-D-xylulose 5-phosphate|isoprenoid anabolism via 1-deoxy-D-xylulose 5-phosphate|isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate						tt	2014-03-11T00:09:55Z						biological_process											owl:Class	
GO:1902870	biolink:NamedThing	negative regulation of amacrine cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation.	got7fsn_ti	negative regulation of amacrine neuron differentiation|inhibition of amacrine neuron differentiation|downregulation of amacrine cell differentiation|downregulation of amacrine neuron differentiation|down regulation of amacrine neuron differentiation|inhibition of amacrine cell differentiation|down-regulation of amacrine cell differentiation|down regulation of amacrine cell differentiation|down-regulation of amacrine neuron differentiation						mr	2014-04-03T15:24:40Z						biological_process											owl:Class	
GO:0072124	biolink:NamedThing	regulation of glomerular mesangial cell proliferation	Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation.	got7fsn_ti							mah	2010-02-22T01:46:12Z						biological_process											owl:Class	
PR:000001397	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045827	biolink:NamedThing	negative regulation of isoprenoid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.	got7fsn_ti	negative regulation of isoprenoid metabolism|downregulation of isoprenoid metabolic process|down-regulation of isoprenoid metabolic process|inhibition of isoprenoid metabolic process|down regulation of isoprenoid metabolic process													biological_process											owl:Class	
GO:0023038	biolink:NamedThing	obsolete signal initiation by diffusible mediator	OBSOLETE. The process in which a diffusible signal causes activation of a receptor.	got7fsn_ti	signal initiation by diffusible mediator				This term was made obsolete because the meaning of the term is ambiguous.	GO:0048018|GO:0038001|GO:0007165|GO:0038023		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:2000582	biolink:NamedThing	obsolete positive regulation of microtubule motor activity, plus-end-directed	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.	got7fsn_ti	positive regulation of plus-end-directed kinesin ATPase activity|positive regulation of ATP-dependent microtubule motor activity, plus-end-directed|positive regulation of kinesin activity|positive regulation of kinesin ATP phosphohydrolase (plus-end-directed)|positive regulation of plus-end-directed microtubule motor activity	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140660	bf	2011-04-05T08:39:52Z		True				biological_process											owl:Class	
GO:1900270	biolink:NamedThing	positive regulation of reverse transcription	Any process that activates or increases the frequency, rate or extent of reverse transcription.	got7fsn_ti	up regulation of reverse transcription|up-regulation of reverse transcription|activation of reverse transcription|upregulation of reverse transcription						tb	2012-04-03T11:13:43Z						biological_process											owl:Class	
GO:1904142	biolink:NamedThing	negative regulation of carotenoid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process.	got7fsn_ti	negative regulation of carotenoid biosynthesis|downregulation of carotenoid synthesis|down-regulation of carotenoid biosynthetic process|downregulation of carotenoid biosynthesis|down-regulation of carotenoid formation|inhibition of carotenoid biosynthesis|down regulation of carotenoid biosynthetic process|down regulation of carotenoid biosynthesis|inhibition of carotenoid formation|negative regulation of carotenoid anabolism|downregulation of carotenoid anabolism|down-regulation of carotenoid synthesis|down regulation of carotenoid anabolism|downregulation of carotenoid biosynthetic process|down regulation of carotenoid synthesis|inhibition of carotenoid synthesis|down-regulation of carotenoid anabolism|downregulation of carotenoid formation|down regulation of carotenoid formation|inhibition of carotenoid biosynthetic process|negative regulation of carotenoid formation|inhibition of carotenoid anabolism|negative regulation of carotenoid synthesis|down-regulation of carotenoid biosynthesis						tb	2015-04-13T19:39:13Z						biological_process											owl:Class	
GO:1904059	biolink:NamedThing	regulation of locomotor rhythm	Any process that modulates the frequency, rate or extent of locomotor rhythm.	got7fsn_ti	regulation of circadian locomotor activity rhythm						sl	2015-03-18T20:38:52Z						biological_process											owl:Class	
GO:1903139	biolink:NamedThing	positive regulation of cell wall integrity MAPK cascade	Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.	got7fsn_ti	activation of Mpk1 cascade|up regulation of MAPKKK cascade involved in cell wall biogenesis|up-regulation of cell integrity MAPK pathway|up regulation of Slt2 cascade|positive regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|positive regulation of Pmk1 MAPK cell integrity signaling|activation of cell integrity MAPK pathway|positive regulation of MAPK cascade involved in cell wall organization or biogenesis|up-regulation of MAPK cascade involved in cell wall organization or biogenesis|up-regulation of MAPK cascade involved in cell wall biogenesis|positive regulation of MAPK cascade involved in cell wall biogenesis|positive regulation of Slt2 cascade|up-regulation of cell wall biogenesis, MAPKKK cascade|positive regulation of cell wall biogenesis, MAPKKK cascade|upregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|activation of MAPK cascade involved in cell wall biogenesis|activation of PMK1-MAPK signal transduction pathway|upregulation of Mpk1 cascade|upregulation of MAPK cascade involved in cell wall organization or biogenesis|activation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|activation of Slt2 cascade|positive regulation of Mpk1 cascade|up regulation of cell wall biogenesis, MAPKKK cascade|up regulation of Mpk1 cascade|activation of Pmk1 MAPK cell integrity signaling|positive regulation of MAPKKK cascade involved in cell wall biogenesis|up regulation of MAPK cascade involved in cell wall organization or biogenesis|upregulation of cell wall biogenesis, MAPKKK cascade|up-regulation of Mpk1 cascade|up-regulation of PMK1-MAPK signal transduction pathway|upregulation of MAPKKK cascade involved in cell wall biogenesis|upregulation of Pmk1 MAPK cell integrity signaling|upregulation of PMK1-MAPK signal transduction pathway|activation of cell wall biogenesis, MAPKKK cascade|up-regulation of Pmk1 MAPK cell integrity signaling|activation of MAPKKK cascade involved in cell wall biogenesis|positive regulation of cell integrity MAPK pathway|up-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|upregulation of Slt2 cascade|positive regulation of PMK1-MAPK signal transduction pathway|up-regulation of Slt2 cascade|up regulation of Pmk1 MAPK cell integrity signaling|up-regulation of MAPKKK cascade involved in cell wall biogenesis|up regulation of PMK1-MAPK signal transduction pathway|activation of MAPK cascade involved in cell wall organization or biogenesis|up regulation of cell integrity MAPK pathway|upregulation of cell integrity MAPK pathway|up regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|upregulation of MAPK cascade involved in cell wall biogenesis|up regulation of MAPK cascade involved in cell wall biogenesis	https://github.com/geneontology/go-ontology/issues/20131					mah	2014-07-01T10:22:05Z						biological_process											owl:Class	
GO:0052017	biolink:NamedThing	obsolete catabolism by symbiont of host xylan	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of host xylan	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1990754	biolink:NamedThing	obsolete GABAergic neuronal action potential	OBSOLETE. An action potential that occurs in a GABAergic neuron.	got7fsn_ti	GABAergic neuronal action potential				This term was obsoleted at the TermGenie Gatekeeper stage.		pg	2015-05-28T08:58:42Z		True				biological_process											owl:Class	
GO:0018963	biolink:NamedThing	phthalate metabolic process	The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses.	got7fsn_ti	phthalic acid metabolic process|phthalate metabolism|phthalic acid metabolism											UM-BBD_pathwayID:pth		biological_process											owl:Class	
GO:1905194	biolink:NamedThing	positive regulation of chloroplast fission	Any process that activates or increases the frequency, rate or extent of chloroplast fission.	got7fsn_ti	activation of chloroplast fission|up-regulation of chloroplast division|upregulation of chloroplast fission|activation of chloroplast division|up regulation of chloroplast fission|up-regulation of chloroplast fission|up regulation of chloroplast division|positive regulation of chloroplast division|upregulation of chloroplast division				Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments.		lr	2016-05-10T19:07:51Z						biological_process											owl:Class	
GO:0043950	biolink:NamedThing	positive regulation of cAMP-mediated signaling	Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.	got7fsn_ti	positive regulation of cAMP-mediated signalling													biological_process											owl:Class	
GO:0030392	biolink:NamedThing	fructosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.	got7fsn_ti	fructosamine degradation|fructosamine breakdown|fructosamine catabolism													biological_process											owl:Class	
GO:0140212	biolink:NamedThing	regulation of long-chain fatty acid import into cell	Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell.	got7fsn_ti							pg	2018-04-10T15:10:41Z						biological_process											owl:Class	
GO:0009400	biolink:NamedThing	obsolete signal transducer, downstream of receptor, with serine/threonine phosphatase activity	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.	got7fsn_ti	receptor signalling protein serine/threonine phosphatase activity|receptor signaling protein serine/threonine phosphatase activity	https://github.com/geneontology/go-ontology/issues/14232			This term was obsoleted because it was not clearly defined.					True				molecular_function											owl:Class	
GO:0075299	biolink:NamedThing	positive regulation of zygospore formation	Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0014708	biolink:NamedThing	regulation of somitomeric trunk muscle development	Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.	got7fsn_ti														biological_process											owl:Class	
GO:0019375	biolink:NamedThing	galactolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.	got7fsn_ti	galactolipid biosynthesis|galactolipid anabolism|galactolipid formation|galactolipid synthesis													biological_process											owl:Class	
GO:0008600	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903839	biolink:NamedThing	positive regulation of mRNA 3'-UTR binding	Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding.	got7fsn_ti	positive regulation of mRNA 3' UTR binding|activation of mRNA 3'-UTR binding|up-regulation of mRNA 3' UTR binding|activation of mRNA 3' UTR binding|up regulation of mRNA 3'-UTR binding|up-regulation of mRNA 3'-UTR binding|upregulation of mRNA 3'-UTR binding|up regulation of mRNA 3' UTR binding|upregulation of mRNA 3' UTR binding						als	2015-01-22T11:54:17Z						biological_process											owl:Class	
GO:0002617	biolink:NamedThing	negative regulation of macrophage antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.	got7fsn_ti	down-regulation of macrophage antigen processing and presentation|downregulation of macrophage antigen processing and presentation|inhibition of macrophage antigen processing and presentation|down regulation of macrophage antigen processing and presentation													biological_process											owl:Class	
GO:0071269	biolink:NamedThing	L-homocysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid.	got7fsn_ti	L-homocysteine formation|L-homocysteine synthesis|L-homocysteine anabolism|L-homocysteine biosynthesis						mah	2009-12-09T05:36:37Z						biological_process											owl:Class	
GO:0050950	biolink:NamedThing	positive regulation of late stripe melanocyte differentiation	Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation.	got7fsn_ti	up-regulation of late stripe melanocyte differentiation|stimulation of late stripe melanocyte differentiation|positive regulation of late stripe melanophore differentiation|activation of late stripe melanocyte differentiation|upregulation of late stripe melanocyte differentiation|up regulation of late stripe melanocyte differentiation													biological_process											owl:Class	
GO:0045408	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902016	biolink:NamedThing	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.	got7fsn_ti	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid synthesis|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid formation|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid anabolism|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis						tb	2013-03-22T15:43:59Z						biological_process											owl:Class	
GO:0046268	biolink:NamedThing	obsolete toluene-4-sulfonate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule.	got7fsn_ti	toluene-4-sulfonate synthesis|4-toluenesulfonate biosynthetic process|toluene-4-sulphonate biosynthetic process|toluene-4-sulfonate biosynthesis|4-toluenesulfonate biosynthesis|toluene-4-sulfonate formation|toluene-4-sulfonate anabolism|toluene-4-sulphonate biosynthesis|toluene-4-sulfonate biosynthetic process			GO:0018972	This term was made obsolete because toluene-4-sulfonate is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1905949	biolink:NamedThing	negative regulation of calcium ion import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane.	got7fsn_ti	down-regulation of calcium ion import across plasma membrane|down regulation of calcium ion import across plasma membrane|inhibition of calcium ion import across plasma membrane|downregulation of calcium ion import across plasma membrane				An example of this is PPP3CA in human (Q08209) in PMID:17640527 (inferred from direct assay).		bhm	2017-02-17T09:42:30Z						biological_process											owl:Class	
GO:0006679	biolink:NamedThing	glucosylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.	got7fsn_ti	glucosylceramide anabolism|glucosylceramide synthesis|glucosylceramide biosynthesis|glucosylceramide formation													biological_process											owl:Class	
GO:1905216	biolink:NamedThing	positive regulation of RNA binding	Any process that activates or increases the frequency, rate or extent of RNA binding.	got7fsn_ti	activation of RNA binding|up regulation of RNA binding|up-regulation of RNA binding|upregulation of RNA binding						bf	2016-06-06T10:21:12Z						biological_process											owl:Class	
GO:1900952	biolink:NamedThing	positive regulation of 18-methylnonadec-1-ene biosynthetic process	Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.	got7fsn_ti	up-regulation of 18-methylnonadec-1-ene synthesis|positive regulation of 18-methylnonadec-1-ene synthesis|upregulation of 18-methylnonadec-1-ene formation|up-regulation of 18-methylnonadec-1-ene biosynthesis|upregulation of 18-methylnonadec-1-ene biosynthetic process|up-regulation of 18-methylnonadec-1-ene anabolism|positive regulation of 18-methylnonadec-1-ene formation|activation of 18-methylnonadec-1-ene biosynthesis|up regulation of 18-methylnonadec-1-ene biosynthesis|activation of 18-methylnonadec-1-ene synthesis|up-regulation of 18-methylnonadec-1-ene formation|up regulation of 18-methylnonadec-1-ene synthesis|up regulation of 18-methylnonadec-1-ene formation|up-regulation of 18-methylnonadec-1-ene biosynthetic process|upregulation of 18-methylnonadec-1-ene biosynthesis|up regulation of 18-methylnonadec-1-ene anabolism|activation of 18-methylnonadec-1-ene formation|activation of 18-methylnonadec-1-ene biosynthetic process|up regulation of 18-methylnonadec-1-ene biosynthetic process|positive regulation of 18-methylnonadec-1-ene anabolism|upregulation of 18-methylnonadec-1-ene synthesis|upregulation of 18-methylnonadec-1-ene anabolism|positive regulation of 18-methylnonadec-1-ene biosynthesis|activation of 18-methylnonadec-1-ene anabolism						tt	2012-06-14T03:24:02Z						biological_process											owl:Class	
GO:0046067	biolink:NamedThing	dGDP catabolic process	The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).	got7fsn_ti	dGDP degradation|dGDP breakdown|dGDP catabolism													biological_process											owl:Class	
GO:1900377	biolink:NamedThing	negative regulation of secondary metabolite biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process.	got7fsn_ti	downregulation of secondary metabolite biosynthetic process|inhibition of secondary metabolite biosynthetic process|down-regulation of secondary metabolite biosynthetic process|inhibition of secondary metabolite biosynthesis|down regulation of secondary metabolite biosynthesis|down-regulation of secondary metabolite biosynthesis|negative regulation of secondary metabolite biosynthesis|down regulation of secondary metabolite biosynthetic process|downregulation of secondary metabolite biosynthesis						di	2012-04-17T01:55:32Z						biological_process											owl:Class	
GO:0048549	biolink:NamedThing	positive regulation of pinocytosis	Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.	got7fsn_ti	up regulation of pinocytosis|activation of pinocytosis|stimulation of pinocytosis|up-regulation of pinocytosis|upregulation of pinocytosis													biological_process											owl:Class	
GO:0045310	biolink:NamedThing	obsolete phosphoserine/phosphothreonine binding	OBSOLETE. Interacting selectively with a phosphorylated serine or threonine residue within a protein.	got7fsn_ti	phosphoserine/phosphothreonine binding				This term was made obsolete because it represents two functions.	GO:0050815|GO:0050816				True				molecular_function											owl:Class	
GO:0038074	biolink:NamedThing	obsolete MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion	OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.	got7fsn_ti	MAPK phosphatase activity involved in regulation of conjugation with cellular fusion				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:31:57Z		True				molecular_function											owl:Class	
GO:0005972	biolink:NamedThing	obsolete fibrinogen alpha chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	fibrinogen alpha chain				This term was made obsolete because it represents a single gene product and not a complex.	GO:0005577				True	GO:0008005			cellular_component											owl:Class	
GO:0045963	biolink:NamedThing	negative regulation of dopamine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.	got7fsn_ti	inhibition of dopamine metabolic process|down regulation of dopamine metabolic process|downregulation of dopamine metabolic process|negative regulation of dopamine metabolism|down-regulation of dopamine metabolic process													biological_process											owl:Class	
GO:0045872	biolink:NamedThing	obsolete positive regulation of rhodopsin gene expression	OBSOLETE. Any process that activates or increases the frequency, rate or extent of rhodopsin gene expression.	got7fsn_ti	upregulation of rhodopsin gene activity|stimulation of rhodopsin gene activity|activation of rhodopsin gene activity|up regulation of rhodopsin gene activity|up-regulation of rhodopsin gene activity|positive regulation of rhodopsin gene activity				This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0045944				True				biological_process											owl:Class	
GO:0006130	biolink:NamedThing	obsolete 6-phosphofructokinase reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	6-phosphofructokinase reduction				This term was made obsolete because the term string was ambiguous and the term may represent a molecular function.	GO:0022900|GO:0003872				True				biological_process											owl:Class	
GO:0046236	biolink:NamedThing	mandelate biosynthetic process	The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.	got7fsn_ti	mandelate biosynthesis|mandelate synthesis|mandelate formation|mandelate anabolism													biological_process											owl:Class	
GO:0019433	biolink:NamedThing	triglyceride catabolic process	The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.	got7fsn_ti	triacylglycerol catabolism|triacylglycerol catabolic process|triglyceride breakdown|triglyceride degradation|triglyceride catabolism											MetaCyc:LIPAS-PWY		biological_process											owl:Class	
GO:0002864	biolink:NamedThing	regulation of acute inflammatory response to antigenic stimulus	Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0042453	biolink:NamedThing	deoxyguanosine metabolic process	The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.	got7fsn_ti	deoxyguanosine metabolism													biological_process											owl:Class	
GO:1901286	biolink:NamedThing	iron-sulfur-molybdenum cofactor metabolic process	The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.	got7fsn_ti	iron-molybdenum cofactor metabolism|FeMo-co metabolic process|FeMo-co metabolism|iron-sulfur-molybdenum cofactor metabolism|iron-molybdenum cofactor metabolic process						yaf	2012-08-17T15:39:14Z						biological_process											owl:Class	
GO:1904882	biolink:NamedThing	regulation of telomerase catalytic core complex assembly	Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly.	got7fsn_ti	regulation of TERT-TERC complex assembly|regulation of telomerase catalytic core complex formation|regulation of TERT-TERC complex formation						rph	2016-01-05T10:36:01Z						biological_process											owl:Class	
GO:0055026	biolink:NamedThing	negative regulation of cardiac muscle tissue development	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development.	got7fsn_ti	down regulation of cardiac muscle development|inhibition of cardiac muscle development|downregulation of cardiac muscle development|down-regulation of cardiac muscle development|negative regulation of heart muscle development													biological_process											owl:Class	
PO:0006085	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901291	biolink:NamedThing	negative regulation of double-strand break repair via single-strand annealing	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing.	got7fsn_ti	downregulation of double-strand break repair via single-strand annealing|inhibition of double-strand break repair via single-strand annealing|down regulation of double-strand break repair via single-strand annealing|down-regulation of double-strand break repair via single-strand annealing						sart	2012-08-20T09:03:03Z						biological_process											owl:Class	
GO:0015307	biolink:NamedThing	obsolete drug:proton antiporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out).	got7fsn_ti	carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|drug:hydrogen antiporter activity				This term was obsoleted because it is not possible to state that every case of transmembrane transport for a specific chemical constitutes a drug transport.					True				molecular_function											owl:Class	
GO:0045739	biolink:NamedThing	positive regulation of DNA repair	Any process that activates or increases the frequency, rate or extent of DNA repair.	got7fsn_ti	stimulation of DNA repair|activation of DNA repair|up-regulation of DNA repair|up regulation of DNA repair|upregulation of DNA repair													biological_process											owl:Class	
GO:0030328	biolink:NamedThing	prenylcysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.	got7fsn_ti	prenylcysteine degradation|prenylcysteine breakdown|prenylcysteine catabolism													biological_process											owl:Class	
GO:1902059	biolink:NamedThing	negative regulation of sporocarp development involved in sexual reproduction	Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction.	got7fsn_ti	inhibition of perfect stage fruiting body development|down regulation of fruiting body development involved in sexual reproduction|down regulation of fruiting body formation involved in sexual reproduction|down regulation of sporocarp development involved in sexual reproduction|downregulation of fruiting body development involved in sexual reproduction|down-regulation of perfect stage fruiting body development|downregulation of perfect stage fruiting body development|down regulation of perfect stage fruiting body development|inhibition of fruiting body formation involved in sexual reproduction|negative regulation of perfect stage fruiting body development|downregulation of fruiting body formation involved in sexual reproduction|down-regulation of ascus development|inhibition of sporocarp development involved in sexual reproduction|downregulation of ascus development|down-regulation of fruiting body formation involved in sexual reproduction|negative regulation of fruiting body development involved in sexual reproduction|inhibition of ascus development|downregulation of sporocarp development involved in sexual reproduction|down-regulation of sporocarp development involved in sexual reproduction|negative regulation of ascus development|negative regulation of fruiting body formation involved in sexual reproduction|inhibition of fruiting body development involved in sexual reproduction|down-regulation of fruiting body development involved in sexual reproduction|down regulation of ascus development						di	2013-04-16T04:08:42Z						biological_process											owl:Class	
GO:0075180	biolink:NamedThing	obsolete regulation of transcription in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22014			This term was obsoleted because it represents a GO-CAM model.	GO:0006355				True				biological_process											owl:Class	
GO:0046013	biolink:NamedThing	regulation of T cell homeostatic proliferation	Any process that modulates the frequency, rate or extent of resting T cell proliferation.	got7fsn_ti	regulation of T-cell homeostatic proliferation|regulation of resting T cell proliferation|regulation of T lymphocyte homeostatic proliferation|regulation of T-lymphocyte homeostatic proliferation													biological_process											owl:Class	
GO:2000412	biolink:NamedThing	positive regulation of thymocyte migration	Any process that activates or increases the frequency, rate or extent of thymocyte migration.	got7fsn_ti	positive regulation of immature T cell migration|positive regulation of thymic lymphocyte migration|positive regulation of immature T lymphocyte migration|positive regulation of immature T-lymphocyte migration|positive regulation of immature T-cell migration						mah	2011-02-23T01:34:23Z						biological_process											owl:Class	
GO:1901079	biolink:NamedThing	positive regulation of relaxation of muscle	Any process that activates or increases the frequency, rate or extent of relaxation of muscle.	got7fsn_ti	up regulation of relaxation of muscle|upregulation of relaxation of muscle|activation of relaxation of muscle|up-regulation of relaxation of muscle						jl	2012-07-04T10:45:02Z						biological_process											owl:Class	
GO:1902499	biolink:NamedThing	positive regulation of protein autoubiquitination	Any process that activates or increases the frequency, rate or extent of protein autoubiquitination.	got7fsn_ti	up regulation of protein autoubiquitinylation|positive regulation of protein auto-ubiquitination|positive regulation of protein autoubiquitinylation|activation of protein auto-ubiquitination|up-regulation of protein auto-ubiquitination|upregulation of protein auto-ubiquitinylation|activation of protein autoubiquitination|up regulation of protein self-ubiquitinylation|positive regulation of protein self-ubiquitination|activation of protein self-ubiquitinylation|activation of protein autoubiquitinylation|up-regulation of protein self-ubiquitinylation|up regulation of protein auto-ubiquitinylation|activation of protein self-ubiquitination|activation of protein auto-ubiquitinylation|up-regulation of protein autoubiquitinylation|up-regulation of protein auto-ubiquitinylation|upregulation of protein self-ubiquitinylation|up regulation of protein self-ubiquitination|up-regulation of protein self-ubiquitination|up-regulation of protein autoubiquitination|upregulation of protein autoubiquitinylation|positive regulation of protein self-ubiquitinylation|upregulation of protein self-ubiquitination|up regulation of protein auto-ubiquitination|upregulation of protein autoubiquitination|upregulation of protein auto-ubiquitination|positive regulation of protein auto-ubiquitinylation|up regulation of protein autoubiquitination						rb	2013-11-13T21:03:37Z						biological_process											owl:Class	
GO:2000224	biolink:NamedThing	regulation of testosterone biosynthetic process	Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.	got7fsn_ti							yaf	2010-11-09T10:38:33Z						biological_process											owl:Class	
GO:1900358	biolink:NamedThing	negative regulation of nigerotriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport.	got7fsn_ti	down regulation of nigerotriose transport|down-regulation of nigerotriose transport|downregulation of nigerotriose transport|inhibition of nigerotriose transport						tt	2012-04-06T02:18:21Z						biological_process											owl:Class	
GO:0033672	biolink:NamedThing	positive regulation of NAD+ kinase activity	Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.	got7fsn_ti	up-regulation of NAD+ kinase activity|up regulation of NAD+ kinase activity|stimulation of NAD+ kinase activity|NAD+ kinase activator|upregulation of NAD+ kinase activity													biological_process											owl:Class	
GO:0070597	biolink:NamedThing	cell wall (1->3)-alpha-glucan metabolic process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.	got7fsn_ti	cell wall alpha-1,3 glucan metabolism|cell wall alpha-1,3 glucan metabolic process|cell wall 1,3-alpha-glucan metabolism|cell wall 1,3-alpha-glucan metabolic process						mah	2009-04-28T04:03:00Z						biological_process											owl:Class	
GO:1903494	biolink:NamedThing	response to dehydroepiandrosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.	got7fsn_ti							mr	2014-09-25T17:01:18Z						biological_process											owl:Class	
GO:0032229	biolink:NamedThing	negative regulation of synaptic transmission, GABAergic	Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).	got7fsn_ti	downregulation of synaptic transmission, GABAergic|down regulation of synaptic transmission, GABAergic|inhibition of synaptic transmission, GABAergic|down-regulation of synaptic transmission, GABAergic													biological_process											owl:Class	
GO:0150147	biolink:NamedThing	cell-cell junction disassembly	The disaggregation of a cell-cell junction into its constituent components.	got7fsn_ti							bc	2019-12-08T11:16:14Z						biological_process											owl:Class	
GO:1903476	biolink:NamedThing	protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti	protein localization to cell division site involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis|protein localisation to cell division site involved in mitotic actomyosin contractile ring assembly|protein localization to cell division site involved in contractile ring assembly involved in mitotic cytokinesis						vw	2014-09-23T14:52:37Z						biological_process											owl:Class	
GO:1900974	biolink:NamedThing	regulation of tatiopterin biosynthetic process	Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process.	got7fsn_ti	regulation of tatiopterin formation|regulation of tatiopterin biosynthesis|regulation of tatiopterin anabolism|regulation of tatiopterin synthesis						tt	2012-06-14T04:01:42Z						biological_process											owl:Class	
GO:1904366	biolink:NamedThing	negative regulation of chemokinesis	Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis.	got7fsn_ti	down-regulation of chemokinesis|downregulation of chemokinesis|down regulation of chemokinesis|inhibition of chemokinesis						sl	2015-06-15T22:44:12Z						biological_process											owl:Class	
GO:0003107	biolink:NamedThing	obsolete positive regulation of natriuresis by angiotensin	OBSOLETE. The process in which angiotensin increases the rate of natriuresis indirectly via diuresis. Natriuresis is the process of renal sodium excretion.	got7fsn_ti	positive regulation of natriuresis by angiotensin|angiotensin-mediated positive regulation of natriuresis				This term was made obsolete because the term is misleading.					True				biological_process											owl:Class	
GO:0051854	biolink:NamedThing	obsolete induction in symbiont of tumor, nodule, or growth containing transformed cells	OBSOLETE. The process by which an organism causes the formation in its symbiont organism of an abnormal growth whose cells have been transformed and continue to exist in the absence of the first organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction in symbiont of tumor, nodule, or growth containing transformed cells				This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
GO:0071680	biolink:NamedThing	response to indole-3-methanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.	got7fsn_ti	response to indole-3-carbinol						mah	2010-02-18T04:05:09Z						biological_process											owl:Class	
GO:0045570	biolink:NamedThing	regulation of imaginal disc growth	Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.	got7fsn_ti														biological_process											owl:Class	
GO:1900278	biolink:NamedThing	positive regulation of proteinase activated receptor activity	Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity.	got7fsn_ti	upregulation of proteinase activated receptor activity|up regulation of proteinase activated receptor activity|up-regulation of proteinase activated receptor activity|activation of proteinase activated receptor activity						rl	2012-04-04T01:31:37Z						biological_process											owl:Class	
GO:1901200	biolink:NamedThing	negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress	Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.	got7fsn_ti	negative regulation of calcium ion transport into cytosol involved in cellular salinity response|negative regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress						al	2012-07-27T11:11:09Z						biological_process											owl:Class	
GO:1990855	biolink:NamedThing	obsolete myo-inositol import across plasma membrane	OBSOLETE. The directed movement of myo-inositol from outside of a cell into the intracellular region of a cell across the plasma membrane.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-09-17T16:52:32Z		True				biological_process											owl:Class	
GO:0032409	biolink:NamedThing	regulation of transporter activity	Any process that modulates the activity of a transporter.	got7fsn_ti														biological_process											owl:Class	
GO:0140050	biolink:NamedThing	negative regulation of endocardial cushion to mesenchymal transition	Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition.	got7fsn_ti							pg	2017-06-26T09:02:27Z						biological_process											owl:Class	
GO:0042598	biolink:NamedThing	obsolete vesicular fraction	OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles that are formed when some cells are homogenized.	got7fsn_ti	vesicular fraction				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0031982				True				cellular_component											owl:Class	
GO:0006628	biolink:NamedThing	obsolete mitochondrial translocation	OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import machinery (MOM complex) and the inner membrane import machinery (MIM complex) form translocation contact sites as a part of the membrane preprotein import machinery.	got7fsn_ti	mitochondrial translocation				This term was made obsolete because its definition was equivalent to that of the biological process term 'mitochondrial matrix protein import ; GO:0030150' while the mitochondrial translocation has a broader meaning; this led to mis-annotation.	GO:0006626				True				biological_process											owl:Class	
GO:1904527	biolink:NamedThing	negative regulation of microtubule binding	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding.	got7fsn_ti	down regulation of microtubule/chromatin interaction|down-regulation of microtubule severing activity|down-regulation of microtubule binding|downregulation of microtubule severing activity|inhibition of microtubule/chromatin interaction|down regulation of microtubule binding|negative regulation of microtubule severing activity|downregulation of microtubule/chromatin interaction|downregulation of microtubule binding|inhibition of microtubule severing activity|down regulation of microtubule severing activity|inhibition of microtubule binding|down-regulation of microtubule/chromatin interaction|negative regulation of microtubule/chromatin interaction						als	2015-07-30T10:32:29Z						biological_process											owl:Class	
GO:0060630	biolink:NamedThing	obsolete regulation of M/G1 transition of mitotic cell cycle	OBSOLETE. Any process that modulates the rate, frequency, or extent of M/G1 transition of the mitotic cell cycle, the progression from M phase to G1 phase of the mitotic cell cycle.	got7fsn_ti	regulation of M/G1 transition of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.		dph	2009-05-18T02:48:58Z		True				biological_process											owl:Class	
GO:1904340	biolink:NamedThing	positive regulation of dopaminergic neuron differentiation	Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.	got7fsn_ti	activation of dopaminergic neuron differentiation|upregulation of dopaminergic neuron differentiation|up-regulation of dopaminergic neuron differentiation|up regulation of dopaminergic neuron differentiation						sl	2015-06-11T18:06:32Z						biological_process											owl:Class	
GO:1900273	biolink:NamedThing	positive regulation of long-term synaptic potentiation	Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation.	got7fsn_ti	positive regulation of LTP|up-regulation of long-term potentiation|up regulation of LTP|positive regulation of long-term potentiation|up regulation of long-term potentiation|up-regulation of LTP|activation of long-term potentiation|upregulation of LTP|up regulation of long-term synaptic potentiation|upregulation of long-term synaptic potentiation|activation of LTP|up-regulation of long-term synaptic potentiation|upregulation of long-term potentiation|activation of long-term synaptic potentiation						rl	2012-04-04T07:17:30Z						biological_process											owl:Class	
GO:0000315	biolink:NamedThing	organellar large ribosomal subunit	The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).	got7fsn_ti														cellular_component											owl:Class	
GO:0019039	biolink:NamedThing	obsolete viral-cell fusion molecule activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	viral-cell fusion molecule activity				This term was made obsolete because it represents a gene product.	GO:0050839|GO:0019064				True				molecular_function											owl:Class	
GO:1900213	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process involved in metanephros development	Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.	got7fsn_ti	up regulation of mesenchymal cell apoptosis involved in metanephros development|up-regulation of mesenchymal cell apoptosis involved in metanephros development|positive regulation of mesenchymal cell apoptosis involved in metanephros development|activation of mesenchymal cell apoptosis involved in metanephros development|upregulation of mesenchymal cell apoptosis involved in metanephros development						yaf	2012-03-22T10:53:09Z						biological_process											owl:Class	
GO:1904420	biolink:NamedThing	positive regulation of telomeric loop formation	Any process that activates or increases the frequency, rate or extent of telomeric loop formation.	got7fsn_ti	up regulation of t-loop biosynthesis|up-regulation of telomeric loop formation|positive regulation of t-loop formation|upregulation of t-loop formation|activation of telomeric loop formation|positive regulation of t-loop biosynthesis|upregulation of telomeric loop formation|activation of t-loop biosynthesis|up-regulation of t-loop biosynthesis|up regulation of t-loop formation|upregulation of t-loop biosynthesis|up-regulation of t-loop formation|up regulation of telomeric loop formation|activation of t-loop formation						nc	2015-07-01T10:40:35Z						biological_process											owl:Class	
GO:0052097	biolink:NamedThing	obsolete interspecies quorum sensing	OBSOLETE. The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules.	got7fsn_ti					The reason for obsoletion is that this term was an unnecessary grouping term.					True				biological_process											owl:Class	
GO:1905250	biolink:NamedThing	obsolete positive regulation of memory	OBSOLETE. Any process that activates or increases the frequency, rate or extent of memory.	got7fsn_ti	enhancement of memory				This term was obsoleted at the TermGenie Gatekeeper stage.		ha	2016-06-09T13:54:53Z		True				biological_process											owl:Class	
GO:0021836	biolink:NamedThing	chemorepulsion involved in postnatal olfactory bulb interneuron migration	The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.	got7fsn_ti	negative chemotaxis involved in postnatal olfactory bulb interneuron migration													biological_process											owl:Class	
GO:0090154	biolink:NamedThing	positive regulation of sphingolipid biosynthetic process	Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	got7fsn_ti							tb	2009-12-08T03:27:33Z						biological_process											owl:Class	
GO:1902745	biolink:NamedThing	positive regulation of lamellipodium organization	Any process that activates or increases the frequency, rate or extent of lamellipodium organization.	got7fsn_ti	upregulation of lamellipodium organization|activation of lamellipodium organization|up regulation of lamellipodium organization|up-regulation of lamellipodium organization						als	2014-02-28T16:27:49Z						biological_process											owl:Class	
GO:0019984	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071581	biolink:NamedThing	regulation of zinc ion transmembrane import	Any process that modulates the frequency, rate or extent of zinc ion import.	got7fsn_ti							mah	2010-01-28T03:09:19Z						biological_process											owl:Class	
GO:0140669	biolink:NamedThing	negative regulation of oxytocin production	Any process that stops, prevents, or reduces the rate of production of oxytocin.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21535					pg	2021-06-24T11:31:45Z						biological_process											owl:Class	
GO:1901507	biolink:NamedThing	negative regulation of acylglycerol transport	Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport.	got7fsn_ti	inhibition of acylglycerol transport|down regulation of glyceride transport|downregulation of acylglycerol transport|down-regulation of acylglycerol transport|down-regulation of glyceride transport|negative regulation of glyceride transport|inhibition of glyceride transport|down regulation of acylglycerol transport|downregulation of glyceride transport						sart	2012-10-17T11:06:18Z						biological_process											owl:Class	
GO:1905065	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation.	got7fsn_ti	positive regulation of VSMC differentiation|up regulation of vascular smooth muscle cell differentiation|up-regulation of vascular smooth muscle cell differentiation|up-regulation of VSMC differentiation|up-regulation of vascular associated smooth muscle cell differentiation|upregulation of vascular associated smooth muscle cell differentiation|upregulation of vascular smooth muscle cell differentiation|activation of vascular associated smooth muscle cell differentiation|positive regulation of vascular smooth muscle cell differentiation|up regulation of VSMC differentiation|activation of vascular smooth muscle cell differentiation|upregulation of VSMC differentiation|activation of VSMC differentiation|up regulation of vascular associated smooth muscle cell differentiation						rph	2016-03-21T11:15:13Z						biological_process											owl:Class	
GO:0042758	biolink:NamedThing	long-chain fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of long-chain fatty acids, a fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain fatty acid degradation|long-chain fatty acid catabolism|long-chain fatty acid breakdown													biological_process											owl:Class	
GO:1905445	biolink:NamedThing	positive regulation of clathrin coat assembly	Any process that activates or increases the frequency, rate or extent of clathrin coat assembly.	got7fsn_ti	up regulation of clathrin cage assembly|positive regulation of clathrin cage assembly|upregulation of clathrin cage assembly|up-regulation of clathrin cage assembly|activation of clathrin coat assembly|activation of clathrin cage assembly|upregulation of clathrin coat assembly|up regulation of clathrin coat assembly|up-regulation of clathrin coat assembly						bf	2016-09-15T14:38:38Z						biological_process											owl:Class	
GO:1900443	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.	got7fsn_ti							di	2012-04-25T05:56:18Z						biological_process											owl:Class	
GO:0005045	biolink:NamedThing	obsolete endoplasmic reticulum receptor activity	OBSOLETE. A receptor in the endoplasmic reticulum.	got7fsn_ti	endoplasmic reticulum receptor activity				This term was made obsolete because it represents cellular component and molecular function information.	GO:0038024				True				molecular_function											owl:Class	
GO:0030852	biolink:NamedThing	regulation of granulocyte differentiation	Any process that modulates the frequency, rate or extent of granulocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1902434	biolink:NamedThing	sulfate import across plasma membrane	The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	sulphate import into cell|sulfate import into cell						mah	2013-10-07T14:12:38Z						biological_process											owl:Class	
GO:0080010	biolink:NamedThing	obsolete regulation of oxygen and reactive oxygen species metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).	got7fsn_ti	regulation of oxygen and reactive oxygen species metabolic process				This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together.	GO:2000374|GO:2000377				True				biological_process											owl:Class	
GO:1990492	biolink:NamedThing	obsolete mitotic cell cycle checkpoint inhibiting CAR assembly	OBSOLETE. A Mad2-dependent mitotic cell cycle checkpoint which delays cytokinetic actinomycin ring assembly if there is a delay in early M-phase.	got7fsn_ti	Mad2-dependent mitotic cell cycle checkpoint|mitotic cell cycle checkpoint inhibiting cytokinetic actomyosin ring assembly				This term was obsoleted because it does not represent a specific process.		vw	2014-09-23T12:43:22Z		True				biological_process											owl:Class	
GO:1900760	biolink:NamedThing	negative regulation of sterigmatocystin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process.	got7fsn_ti	downregulation of sterigmatocystin biosynthetic process|down-regulation of sterigmatocystin formation|down regulation of sterigmatocystin biosynthetic process|down regulation of sterigmatocystin formation|down-regulation of sterigmatocystin synthesis|down regulation of sterigmatocystin anabolism|down-regulation of sterigmatocystin biosynthetic process|negative regulation of sterigmatocystin synthesis|negative regulation of sterigmatocystin biosynthesis|downregulation of sterigmatocystin synthesis|down regulation of sterigmatocystin biosynthesis|inhibition of sterigmatocystin biosynthesis|inhibition of sterigmatocystin anabolism|inhibition of sterigmatocystin formation|down regulation of sterigmatocystin synthesis|downregulation of sterigmatocystin formation|inhibition of sterigmatocystin synthesis|negative regulation of sterigmatocystin formation|downregulation of sterigmatocystin biosynthesis|down-regulation of sterigmatocystin biosynthesis|inhibition of sterigmatocystin biosynthetic process|negative regulation of sterigmatocystin anabolism|downregulation of sterigmatocystin anabolism|down-regulation of sterigmatocystin anabolism						di	2012-06-04T08:38:30Z						biological_process											owl:Class	
GO:1904221	biolink:NamedThing	negative regulation of serine C-palmitoyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity.	got7fsn_ti	negative regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|negative regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|down-regulation of SPT|down regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|downregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|down-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|downregulation of SPT|downregulation of serine C-palmitoyltransferase activity|inhibition of SPT|downregulation of 3-oxosphinganine synthetase activity|down-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|down-regulation of 3-oxosphinganine synthetase activity|down regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|inhibition of 3-oxosphinganine synthetase activity|negative regulation of 3-oxosphinganine synthetase activity|inhibition of acyl-CoA:serine C-2 acyltransferase decarboxylating|down regulation of SPT|negative regulation of SPT|inhibition of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|down regulation of 3-oxosphinganine synthetase activity|downregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|down regulation of serine C-palmitoyltransferase activity|down-regulation of serine C-palmitoyltransferase activity|inhibition of serine C-palmitoyltransferase activity				Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability		rl	2015-05-15T08:27:39Z						biological_process											owl:Class	
GO:0019599	biolink:NamedThing	(R)-4-hydroxymandelate catabolic process	The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.	got7fsn_ti	(R)-4-hydroxymandelate catabolism|(R)-4-hydroxymandelate degradation|(R)-4-hydroxymandelate breakdown											MetaCyc:4-HYDROXYMANDELATE-DEGRADATION-PWY		biological_process											owl:Class	
GO:0006558	biolink:NamedThing	L-phenylalanine metabolic process	The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.	got7fsn_ti	L-phenylalanine metabolism|phenylalanine metabolism|phenylalanine metabolic process													biological_process											owl:Class	
GO:0006852	biolink:NamedThing	obsolete mitochondrial sodium/calcium ion exchange	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	mitochondrial sodium/calcium ion exchange|mitochondrial sodium/calcium exchange				This term was made obsolete because it represents function rather than a process.	GO:0006839|GO:0006816|GO:0006814|GO:0005432				True				biological_process											owl:Class	
GO:0060057	biolink:NamedThing	apoptotic process involved in mammary gland involution	Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death.	got7fsn_ti	apoptosis involved in mammary gland involution													biological_process											owl:Class	
GO:0120038	biolink:NamedThing	obsolete plasma membrane bounded cell projection part	OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13298				GO:0120025	krc	2017-04-28T17:20:43Z		True				cellular_component											owl:Class	
GO:1902209	biolink:NamedThing	negative regulation of bacterial-type flagellum assembly	Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly.	got7fsn_ti	down regulation of bacterial flagellum assembly|inhibition of bacterial-type flagellum assembly|down-regulation of bacterial flagellum assembly|inhibition of bacterial flagellum assembly|down-regulation of bacterial-type flagellum assembly|downregulation of bacterial flagellum assembly|down regulation of bacterial-type flagellum assembly|downregulation of bacterial-type flagellum assembly|negative regulation of bacterial flagellum assembly						jl	2013-06-11T14:20:24Z						biological_process											owl:Class	
GO:1902286	biolink:NamedThing	semaphorin-plexin signaling pathway involved in dendrite guidance	Any semaphorin-plexin signaling pathway that is involved in dendrite guidance.	got7fsn_ti	semaphorin-plexin signalling pathway involved in dendrite guidance|semaphorin-plexin signaling pathway involved in dendritic guidance|semaphorin-plexin signalling pathway involved in dendritic guidance						pr	2013-07-08T16:06:55Z						biological_process											owl:Class	
GO:1900552	biolink:NamedThing	asperfuranone metabolic process	The chemical reactions and pathways involving asperfuranone.	got7fsn_ti	asperfuranone metabolism						di	2012-05-15T01:30:48Z						biological_process											owl:Class	
GO:1905898	biolink:NamedThing	positive regulation of response to endoplasmic reticulum stress	Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.	got7fsn_ti	up regulation of ER stress response|activation of cellular response to endoplasmic reticulum stress|positive regulation of ER stress response|up regulation of response to endoplasmic reticulum stress|up regulation of cellular response to endoplasmic reticulum stress|activation of response to endoplasmic reticulum stress|upregulation of ER stress response|up regulation of response to ER stress|up-regulation of response to ER stress|positive regulation of response to ER stress|positive regulation of cellular response to endoplasmic reticulum stress|up-regulation of ER stress response|up-regulation of cellular response to endoplasmic reticulum stress|upregulation of response to ER stress|upregulation of response to endoplasmic reticulum stress|activation of response to ER stress|up-regulation of response to endoplasmic reticulum stress|activation of ER stress response|upregulation of cellular response to endoplasmic reticulum stress						bc	2017-02-01T11:43:03Z						biological_process											owl:Class	
GO:0006823	biolink:NamedThing	obsolete heavy metal ion transport	OBSOLETE. The directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	got7fsn_ti	heavy metal ion transport				This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0030001				True				biological_process											owl:Class	
GO:0061280	biolink:NamedThing	epithelial cell migration involved in mesonephric proximal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.	got7fsn_ti							dph	2010-09-02T01:23:43Z						biological_process											owl:Class	
GO:1900178	biolink:NamedThing	negative regulation of aflatoxin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process.	got7fsn_ti	down-regulation of aflatoxin formation|negative regulation of aflatoxin formation|down regulation of aflatoxin anabolism|down regulation of aflatoxin synthesis|downregulation of aflatoxin anabolism|inhibition of aflatoxin formation|downregulation of aflatoxin biosynthetic process|inhibition of aflatoxin anabolism|down-regulation of aflatoxin biosynthesis|downregulation of aflatoxin synthesis|down-regulation of aflatoxin biosynthetic process|down regulation of aflatoxin biosynthetic process|down regulation of aflatoxin biosynthesis|negative regulation of aflatoxin biosynthesis|downregulation of aflatoxin formation|down regulation of aflatoxin formation|negative regulation of aflatoxin anabolism|downregulation of aflatoxin biosynthesis|down-regulation of aflatoxin anabolism|inhibition of aflatoxin biosynthesis|down-regulation of aflatoxin synthesis|negative regulation of aflatoxin synthesis|inhibition of aflatoxin biosynthetic process|inhibition of aflatoxin synthesis						di	2012-03-09T11:23:42Z						biological_process											owl:Class	
GO:0090213	biolink:NamedThing	regulation of radial pattern formation	Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.	got7fsn_ti	regulation of radial pattern specification						tb	2010-01-05T10:59:10Z						biological_process											owl:Class	
GO:0019356	biolink:NamedThing	nicotinate nucleotide biosynthetic process from tryptophan	The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan.	got7fsn_ti	nicotinate nucleotide formation from tryptophan|nicotinate nucleotide synthesis from tryptophan|nicotinate nucleotide anabolism from tryptophan													biological_process											owl:Class	
GO:1901303	biolink:NamedThing	negative regulation of cargo loading into COPII-coated vesicle	Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle.	got7fsn_ti	inhibition of cargo loading into COPII-coated vesicle|negative regulation of cargo loading into COPII vesicle|inhibition of cargo selection into COPII-coated vesicle|down-regulation of cargo loading into COPII-coated vesicle|down regulation of COPII coat-cargo complex assembly|downregulation of cargo loading into COPII-coated vesicle|inhibition of cargo loading into COPII vesicle|negative regulation of COPII coat-cargo complex assembly|inhibition of COPII vesicle protein binding|down-regulation of COPII coat-cargo complex assembly|negative regulation of cargo selection into COPII-coated vesicle|down regulation of cargo loading into COPII vesicle|down-regulation of cargo selection into COPII-coated vesicle|down regulation of cargo selection into COPII-coated vesicle|down-regulation of cargo loading into COPII vesicle|downregulation of cargo selection into COPII-coated vesicle|inhibition of protein sorting into COPII-coated vesicles|down regulation of cargo loading into COPII-coated vesicle|downregulation of cargo loading into COPII vesicle|downregulation of COPII coat-cargo complex assembly|inhibition of COPII coat-cargo complex assembly						bf	2012-08-21T13:05:46Z						biological_process											owl:Class	
GO:0052125	biolink:NamedThing	obsolete energy taxis on or near host	OBSOLETE. The directed movement of a motile cell or organism on or near its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0060663	biolink:NamedThing	apoptotic process involved in salivary gland cavitation	Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.	got7fsn_ti	apoptosis involved in salivary gland cavitation						dph	2009-06-01T08:27:16Z						biological_process											owl:Class	
GO:1905123	biolink:NamedThing	regulation of glucosylceramidase activity	Any process that modulates the frequency, rate or extent of glucosylceramidase activity.	got7fsn_ti	regulation of ceramide glucosidase activity|regulation of GlcCer-beta-glucosidase activity|regulation of glucosylsphingosine beta-glucosidase activity|regulation of beta-glucosylceramidase activity|regulation of beta-D-glucocerebrosidase activity|regulation of beta-glucocerebrosidase activity|regulation of glucosphingosine glucosylhydrolase activity|regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|regulation of psychosine hydrolase activity|regulation of glucosylcerebrosidase activity|regulation of glucosylsphingosine beta-D-glucosidase activity|regulation of acid beta-glucosidase activity|regulation of GCase activity|regulation of glucocerebrosidase activity						bf	2016-04-11T15:44:26Z						biological_process											owl:Class	
GO:1901204	biolink:NamedThing	obsolete regulation of adrenergic receptor signaling pathway involved in heart process	OBSOLETE. Any process that modulates the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.	got7fsn_ti	regulation of beta-adrenergic receptor signalling pathway involved in heart process|regulation of adrenergic receptor signalling pathway involved in heart process	https://github.com/geneontology/go-ontology/issues/14733			This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		hjd	2012-07-30T18:32:51Z		True				biological_process											owl:Class	
GO:0097037	biolink:NamedThing	heme export	The directed movement of heme out of a cell or organelle.	got7fsn_ti							pr	2011-04-11T10:39:22Z						biological_process											owl:Class	
GO:0019680	biolink:NamedThing	L-methylmalonyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA.	got7fsn_ti	L-methylmalonyl-CoA synthesis|L-methylmalonyl-CoA anabolism|L-methylmalonyl-CoA formation|L-methylmalonyl-CoA biosynthesis											MetaCyc:PWY0-43		biological_process											owl:Class	
GO:0009870	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000345	biolink:NamedThing	regulation of hepatocyte proliferation	Any process that modulates the frequency, rate or extent of hepatocyte proliferation.	got7fsn_ti							mah	2011-02-03T10:27:15Z						biological_process											owl:Class	
GO:1905417	biolink:NamedThing	negative regulation of amoeboid sperm motility	Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility.	got7fsn_ti	negative regulation of ameboid sperm motility|inhibition of amoeboid sperm movement|inhibition of ameboid sperm movement|down-regulation of ameboid sperm movement|down-regulation of ameboid sperm motility|inhibition of amoeboid sperm motility|downregulation of amoeboid sperm motility|down regulation of amoeboid sperm motility|inhibition of ameboid sperm motility|negative regulation of amoeboid sperm movement|down-regulation of amoeboid sperm movement|down regulation of ameboid sperm movement|down regulation of ameboid sperm motility|downregulation of ameboid sperm motility|down regulation of amoeboid sperm movement|downregulation of amoeboid sperm movement|negative regulation of ameboid sperm movement|down-regulation of amoeboid sperm motility|downregulation of ameboid sperm movement						pr	2016-09-01T11:28:55Z						biological_process											owl:Class	
GO:1902166	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.	got7fsn_ti	down regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|inhibition of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|down regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis						lb	2013-05-22T12:45:15Z						biological_process											owl:Class	
GO:0090159	biolink:NamedThing	sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization	The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization.	got7fsn_ti	sphingolipid biosynthesis involved in endoplasmic reticulum membrane organisation						tb	2009-12-08T08:31:13Z						biological_process											owl:Class	
GO:1902026	biolink:NamedThing	regulation of cartilage condensation	Any process that modulates the frequency, rate or extent of cartilage condensation.	got7fsn_ti							jl	2013-03-28T17:02:42Z						biological_process											owl:Class	
GO:0006181	biolink:NamedThing	dGMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).	got7fsn_ti	dGMP formation|dGMP biosynthesis|dGMP anabolism|dGMP synthesis													biological_process											owl:Class	
GO:0009436	biolink:NamedThing	glyoxylate catabolic process	The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.	got7fsn_ti	glyoxylate degradation|glyoxylate catabolism|glyoxylate breakdown											MetaCyc:GLYOXDEG-PWY		biological_process											owl:Class	
GO:1903264	biolink:NamedThing	nitrate reductase activity involved in anaerobic electron transport chain	Any nitrate reductase activity that is involved in anaerobic electron transport chain.	got7fsn_ti	nitrite:(acceptor) oxidoreductase involved in anaerobic electron transport chain|nitrate reductase (acceptor) involved in anaerobic electron transport chain|nitrite:acceptor oxidoreductase involved in anaerobic electron transport chain|respiratory nitrate reductase activity involved in anaerobic electron transport chain						dos	2014-08-07T10:07:07Z						molecular_function											owl:Class	
GO:0055056	biolink:NamedThing	D-glucose transmembrane transporter activity	Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other.	got7fsn_ti												Reactome:R-HSA-5632871|Reactome:R-HSA-8981570|Reactome:R-HSA-5339524|Reactome:R-HSA-8981553|Reactome:R-HSA-450095|Reactome:R-HSA-8981574|Reactome:R-HSA-8981564|Reactome:R-HSA-5632804|Reactome:R-HSA-429094		molecular_function											owl:Class	
UBERON:0000021	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045714	biolink:NamedThing	obsolete regulation of low-density lipoprotein particle receptor biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.	got7fsn_ti	regulation of low-density lipoprotein receptor biosynthesis|regulation of LDLr biosynthetic process|regulation of low-density lipoprotein receptor synthesis|regulation of LDLr biosynthesis|regulation of low-density lipoprotein receptor biosynthetic process|regulation of low-density lipoprotein receptor anabolism|regulation of low-density lipoprotein receptor formation	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1905124	biolink:NamedThing	negative regulation of glucosylceramidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity.	got7fsn_ti	down-regulation of beta-glucosylceramidase activity|down-regulation of ceramide glucosidase activity|negative regulation of glucosylcerebrosidase activity|downregulation of glucosylceramidase activity|down regulation of psychosine hydrolase activity|inhibition of beta-glucocerebrosidase activity|downregulation of glucosylcerebrosidase activity|inhibition of glucosylsphingosine beta-glucosidase activity|down regulation of GlcCer-beta-glucosidase activity|downregulation of beta-glucosylceramidase activity|down regulation of glucosylsphingosine beta-D-glucosidase activity|downregulation of glucosylsphingosine beta-glucosidase activity|down regulation of ceramide glucosidase activity|inhibition of glucosylceramidase activity|down-regulation of beta-glucocerebrosidase activity|negative regulation of beta-glucocerebrosidase activity|down regulation of glucocerebrosidase activity|down-regulation of glucosylcerebrosidase activity|inhibition of glucosylcerebrosidase activity|inhibition of GlcCer-beta-glucosidase activity|down-regulation of GlcCer-beta-glucosidase activity|negative regulation of beta-glucosylceramidase activity|down-regulation of psychosine hydrolase activity|down regulation of glucosylcerebrosidase activity|negative regulation of glucocerebrosidase activity|down-regulation of glucosylsphingosine beta-glucosidase activity|negative regulation of psychosine hydrolase activity|down-regulation of acid beta-glucosidase activity|down-regulation of glucocerebrosidase activity|down regulation of acid beta-glucosidase activity|negative regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of glucosylsphingosine beta-D-glucosidase activity|down-regulation of glucosphingosine glucosylhydrolase activity|negative regulation of ceramide glucosidase activity|negative regulation of GlcCer-beta-glucosidase activity|negative regulation of glucosylsphingosine beta-D-glucosidase activity|inhibition of beta-D-glucocerebrosidase activity|inhibition of glucocerebrosidase activity|inhibition of ceramide glucosidase activity|inhibition of acid beta-glucosidase activity|downregulation of beta-glucocerebrosidase activity|down regulation of glucosylceramidase activity|negative regulation of GCase activity|negative regulation of beta-D-glucocerebrosidase activity|down regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|down-regulation of glucosylsphingosine beta-D-glucosidase activity|down regulation of glucosylsphingosine beta-glucosidase activity|downregulation of beta-D-glucocerebrosidase activity|negative regulation of glucosphingosine glucosylhydrolase activity|downregulation of glucosylsphingosine beta-D-glucosidase activity|inhibition of psychosine hydrolase activity|downregulation of psychosine hydrolase activity|downregulation of ceramide glucosidase activity|down regulation of glucosphingosine glucosylhydrolase activity|downregulation of glucosphingosine glucosylhydrolase activity|downregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|down-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|downregulation of GlcCer-beta-glucosidase activity|negative regulation of acid beta-glucosidase activity|down regulation of beta-D-glucocerebrosidase activity|down-regulation of glucosylceramidase activity|downregulation of glucocerebrosidase activity|down regulation of beta-glucosylceramidase activity|down regulation of beta-glucocerebrosidase activity|negative regulation of glucosylsphingosine beta-glucosidase activity|inhibition of glucosphingosine glucosylhydrolase activity|downregulation of acid beta-glucosidase activity|down-regulation of beta-D-glucocerebrosidase activity|inhibition of beta-glucosylceramidase activity						bf	2016-04-11T15:44:35Z						biological_process											owl:Class	
GO:0032438	biolink:NamedThing	melanosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.	got7fsn_ti	melanosome organisation|melanosome organization and biogenesis													biological_process											owl:Class	
GO:2000719	biolink:NamedThing	negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.	got7fsn_ti	negative regulation of maintenance of sister chromatin cohesion at centromere at mitosis|negative regulation of maintenance of centromeric mitotic sister chromatin cohesion|negative regulation of maintenance of mitotic sister chromatin cohesion at centromere						mah	2011-06-03T10:41:14Z						biological_process											owl:Class	
GO:1902690	biolink:NamedThing	positive regulation of NAD metabolic process	Any process that activates or increases the frequency, rate or extent of NAD metabolic process.	got7fsn_ti	up regulation of oxidized nicotinamide adenine dinucleotide metabolism|up-regulation of NAD (oxidized) metabolism|positive regulation of oxidized nicotinamide adenine dinucleotide metabolism|up-regulation of oxidized nicotinamide adenine dinucleotide metabolic process|up regulation of NAD (oxidized) metabolism|upregulation of nicotinamide adenine dinucleotide metabolic process|up regulation of oxidized NAD metabolic process|activation of NAD metabolism|activation of oxidized nicotinamide adenine dinucleotide metabolism|up regulation of oxidized nicotinamide adenine dinucleotide metabolic process|activation of NAD (oxidized) metabolic process|up regulation of NAD (oxidized) metabolic process|up regulation of nicotinamide adenine dinucleotide metabolic process|positive regulation of oxidized nicotinamide adenine dinucleotide metabolic process|upregulation of oxidized NAD metabolic process|activation of NAD phosphorylation and dephosphorylation|up-regulation of nicotinamide adenine dinucleotide metabolism|upregulation of oxidized NAD metabolism|activation of NAD (oxidized) metabolism|up-regulation of nicotinamide adenine dinucleotide metabolic process|upregulation of NAD metabolism|upregulation of oxidized nicotinamide adenine dinucleotide metabolism|up-regulation of NAD metabolism|up-regulation of NAD (oxidized) metabolic process|upregulation of NAD metabolic process|up regulation of nicotinamide adenine dinucleotide metabolism|positive regulation of nicotinamide adenine dinucleotide metabolism|upregulation of NAD (oxidized) metabolism|positive regulation of NAD (oxidized) metabolic process|activation of oxidized NAD metabolic process|up-regulation of oxidized nicotinamide adenine dinucleotide metabolism|activation of nicotinamide adenine dinucleotide metabolic process|positive regulation of NAD phosphorylation and dephosphorylation|activation of oxidized nicotinamide adenine dinucleotide metabolic process|upregulation of NAD (oxidized) metabolic process|positive regulation of NAD (oxidized) metabolism|upregulation of nicotinamide adenine dinucleotide metabolism|up regulation of oxidized NAD metabolism|up-regulation of oxidized NAD metabolic process|positive regulation of oxidized NAD metabolic process|activation of nicotinamide adenine dinucleotide metabolism|activation of oxidized NAD metabolism|upregulation of NAD phosphorylation and dephosphorylation|positive regulation of oxidized NAD metabolism|up-regulation of oxidized NAD metabolism|up-regulation of NAD phosphorylation and dephosphorylation|up regulation of NAD metabolism|positive regulation of nicotinamide adenine dinucleotide metabolic process|up-regulation of NAD metabolic process|positive regulation of NAD metabolism|up regulation of NAD metabolic process|activation of NAD metabolic process|up regulation of NAD phosphorylation and dephosphorylation|upregulation of oxidized nicotinamide adenine dinucleotide metabolic process						di	2014-02-12T18:59:09Z						biological_process											owl:Class	
GO:0060188	biolink:NamedThing	regulation of protein desumoylation	Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.	got7fsn_ti														biological_process											owl:Class	
GO:0007109	biolink:NamedThing	obsolete cytokinesis, completion of separation	OBSOLETE. The process of finishing cell separation, which results in two physically separated cells.	got7fsn_ti	completion of separation involved in cytokinesis|cytokinesis, completion of separation				This term was obsoleted because it was vaguely defined and had very likely been used in error. Consider the child terms of cytokinesis related to ring positioning, assembly, ring constriction etc. which would be more appropriate.					True				biological_process											owl:Class	
GO:1903723	biolink:NamedThing	negative regulation of centriole elongation	Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation.	got7fsn_ti	down-regulation of centriole elongation|downregulation of centriole elongation|down regulation of centriole elongation|inhibition of centriole elongation						als	2014-12-09T16:36:12Z						biological_process											owl:Class	
GO:0075334	biolink:NamedThing	obsolete modulation of symbiont adenylate cyclase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0034019	biolink:NamedThing	obsolete capsanthin/capsorubin synthase activity	OBSOLETE. Catalysis of the reactions: violaxanthin = capsorubin, and antheraxanthin = capsanthin.	got7fsn_ti	ketoxanthophyll synthase activity|violaxanthin-capsorubin isomerase (ketone-forming) activity|capsanthin/capsorubin synthase activity|capsanthin-capsorubin synthase activity|CCS				This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052728|GO:0052727				True				molecular_function											owl:Class	
GO:0044690	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061741	biolink:NamedThing	obsolete chaperone-mediated protein transport involved in chaperone-mediated autophagy	OBSOLETE. The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20850			This term was obsoleted because it represents a function within a process.		dph	2015-10-21T08:56:33Z		True				biological_process											owl:Class	
GO:0019204	biolink:NamedThing	obsolete nucleotide phosphatase activity	OBSOLETE. Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate.	got7fsn_ti	nucleotide phosphatase activity				This term was defined to cover phosphatase activity against polynucleotides, but had subclasses and annotations for phosphatase activity against free nucleotides.  It has therefore been split. Use GO:0098519 (nucleotide phosphatase activity, acting against free nucleotides) or GO:0098518 (polynucleotide phosphatase activity).	GO:0098519|GO:0098518				True				molecular_function											owl:Class	
GO:1901037	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle	OBSOLETE. Any process that regulates transcription such that the target genes are transcribed during the M/G1 transition of the mitotic cell cycle.	got7fsn_ti	regulation of gene-specific transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription during M/G1 transition of mitotic cell cycle|global transcription regulation from Pol II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter involved in M/G1 transition of mitotic cell cycle|regulation of global transcription from Pol II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription from Pol II promoter during M/G1 transition of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.	GO:0006357	pr	2012-06-21T10:09:51Z		True				biological_process											owl:Class	
GO:0032199	biolink:NamedThing	reverse transcription involved in RNA-mediated transposition	The synthesis of DNA from an RNA transposon intermediate.	got7fsn_ti	reverse transcription during retrotransposition													biological_process											owl:Class	
GO:1901981	biolink:NamedThing	phosphatidylinositol phosphate binding	Binding to phosphatidylinositol phosphate.	got7fsn_ti							tb	2013-03-12T18:21:22Z						molecular_function											owl:Class	
GO:2000818	biolink:NamedThing	negative regulation of myoblast proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.	got7fsn_ti							pr	2011-07-12T03:06:04Z						biological_process											owl:Class	
GO:1901948	biolink:NamedThing	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.	got7fsn_ti	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate breakdown|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate degradation|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolism						ms	2013-02-18T15:50:45Z						biological_process											owl:Class	
GO:0097089	biolink:NamedThing	methyl-branched fatty acid metabolic process	The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.	got7fsn_ti	methyl-branched fatty acid metabolism						pr	2011-07-01T01:06:15Z						biological_process											owl:Class	
GO:1900646	biolink:NamedThing	regulation of chanoclavine-I aldehyde biosynthetic process	Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.	got7fsn_ti	regulation of chanoclavine-I aldehyde biosynthesis|regulation of chanoclavine-I aldehyde formation|regulation of chanoclavine-I aldehyde anabolism|regulation of chanoclavine-I aldehyde synthesis						di	2012-05-22T04:04:38Z						biological_process											owl:Class	
GO:1900232	biolink:NamedThing	negative regulation of single-species biofilm formation on inanimate substrate	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.	got7fsn_ti	downregulation of single-species biofilm formation on inanimate substrate|down regulation of single-species biofilm formation on inanimate substrate|inhibition of single-species biofilm formation on inanimate substrate|down-regulation of single-species biofilm formation on inanimate substrate						di	2012-03-23T04:40:45Z						biological_process											owl:Class	
GO:1904111	biolink:NamedThing	obsolete negative regulation of plus-end directed microfilament motor activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of plus-end directed microfilament motor activity.	got7fsn_ti	downregulation of barbed-end directed actin-filament motor activity|downregulation of plus-end directed actin filament motor activity|negative regulation of barbed-end directed actin-filament motor activity|downregulation of plus-end directed microfilament motor activity|down regulation of plus-end directed microfilament motor activity|down regulation of plus-end directed actin-filament motor activity|down-regulation of barbed-end directed actin-filament motor activity|inhibition of plus-end directed actin-filament motor activity|inhibition of plus-end directed actin filament motor activity|down-regulation of plus-end directed actin filament motor activity|negative regulation of plus-end directed actin filament motor activity|inhibition of plus-end directed microfilament motor activity|down regulation of plus-end directed actin filament motor activity|downregulation of plus-end directed actin-filament motor activity|down-regulation of plus-end directed actin-filament motor activity|inhibition of barbed-end directed actin-filament motor activity|negative regulation of plus-end directed actin-filament motor activity|down-regulation of plus-end directed microfilament motor activity|down regulation of barbed-end directed actin-filament motor activity	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140661	kmv	2015-04-03T18:28:30Z		True				biological_process											owl:Class	
GO:0006042	biolink:NamedThing	glucosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.	got7fsn_ti	glucosamine biosynthesis|glucosamine anabolism|chitosamine biosynthetic process|glucosamine formation|glucosamine synthesis|chitosamine biosynthesis													biological_process											owl:Class	
GO:0090359	biolink:NamedThing	negative regulation of abscisic acid biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.	got7fsn_ti	negative regulation of abscisic acid biosynthesis						tb	2010-06-29T02:47:12Z						biological_process											owl:Class	
GO:1903505	biolink:NamedThing	regulation of establishment of actomyosin contractile ring localization involved in mitotic cell cycle	Any process that modulates the frequency, rate or extent of establishment of actomyosin contractile ring localization involved in mitotic cell cycle.	got7fsn_ti							al	2014-10-01T13:59:19Z						biological_process											owl:Class	
GO:2001025	biolink:NamedThing	positive regulation of response to drug	Any process that activates or increases the frequency, rate or extent of response to drug.	got7fsn_ti	positive regulation of drug resistance|positive regulation of drug susceptibility/resistance						yaf	2011-08-19T01:47:27Z						biological_process											owl:Class	
GO:0045885	biolink:NamedThing	obsolete positive regulation of survival gene product expression	OBSOLETE. Any process that activates or increases the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.	got7fsn_ti	positive regulation of survival gene product activity|positive regulation of survival gene product expression|up regulation of survival gene product activity|stimulation of survival gene product activity|upregulation of survival gene product activity|activation of survival gene product activity|positive regulation of survival gene products|up-regulation of survival gene product activity				This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc.					True				biological_process											owl:Class	
GO:0060686	biolink:NamedThing	negative regulation of prostatic bud formation	Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.	got7fsn_ti							dph	2009-06-05T12:35:25Z						biological_process											owl:Class	
GO:2000046	biolink:NamedThing	obsolete regulation of G2 phase of mitotic cell cycle	OBSOLETE. Any process that modulates the frequency, rate or extent of G2 phase of mitotic cell cycle.	got7fsn_ti	regulation of G2 phase of mitotic cell cycle				This term was made obsolete because we felt that phases themselves are not being regulated, it's rather the transitions between phases. If you are trying to make an annotation to x phase, it is likely that the correct process is 'regulation of x/y phase transiition.	GO:0010389	tb	2010-08-19T09:19:18Z		True				biological_process											owl:Class	
GO:0033249	biolink:NamedThing	positive regulation of penicillin catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti	positive regulation of penicillin degradation|positive regulation of penicillin catabolism|positive regulation of penicillin breakdown													biological_process											owl:Class	
GO:0070171	biolink:NamedThing	negative regulation of tooth mineralization	Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.	got7fsn_ti														biological_process											owl:Class	
GO:1990985	biolink:NamedThing	obsolete apoptosis in response to oxidative stress	OBSOLETE. Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to oxidative stress.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		pg	2016-11-17T14:12:17Z		True				biological_process											owl:Class	
GO:0140333	biolink:NamedThing	glycerophospholipid flippase activity	Catalysis of the movement of a glycerophospholipid from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	glycerophospholipid flippase activity (exoplasmic to cytosolic leaftlet)						pg	2019-05-13T11:14:56Z						molecular_function											owl:Class	
GO:0051421	biolink:NamedThing	regulation of endo-1,4-beta-xylanase activity	Any process that modulates the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.	got7fsn_ti	endo-1,4-beta-xylanase regulator|xylanase regulator													biological_process											owl:Class	
GO:1901199	biolink:NamedThing	positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress	Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.	got7fsn_ti	positive regulation of calcium ion transport into cytosol involved in cellular salinity response|positive regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress						al	2012-07-27T11:09:37Z						biological_process											owl:Class	
GO:1903870	biolink:NamedThing	positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.	got7fsn_ti	upregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|activation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|positive regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|upregulation of methylenetetrahydrofolate reductase (NADPH2)|positive regulation of methylenetetrahydrofolate reductase (NADPH2)|positive regulation of N5,N10-methylenetetrahydrofolate reductase activity|up-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|positive regulation of N5,10-methylenetetrahydrofolate reductase activity|activation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|positive regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|upregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|positive regulation of 5,10-CH2-H4folate reductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|upregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|positive regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up regulation of methylenetetrahydrofolate reductase (NADPH2)|positive regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|up-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|activation of 5,10-methylenetetrahydropteroylglutamate reductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|positive regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|up regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|upregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of N5,N10-methylenetetrahydrofolate reductase activity|up-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up-regulation of N5,N10-methylenetetrahydrofolate reductase activity|upregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|upregulation of 5,10-CH(2)-H(4)folate reductase activity|upregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|positive regulation of 5,10-CH(2)-H(4)folate reductase activity|up regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up regulation of 5,10-CH(2)-H(4)folate reductase activity|up regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|activation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|up regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|up-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|upregulation of methylenetetrahydrofolate reductase [NAD(P)H]|upregulation of 5,10-CH2-H4folate reductase activity|activation of methylenetetrahydrofolate reductase (NAD(P)H) activity|up regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|positive regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up-regulation of methylenetetrahydrofolate reductase [NAD(P)H]|activation of methylenetetrahydrofolate reductase [NAD(P)H]|up regulation of N5,10-methylenetetrahydrofolate reductase activity|activation of 5,10-CH2-H4folate reductase activity|up-regulation of 5,10-CH(2)-H(4)folate reductase activity|activation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up-regulation of 5,10-CH2-H4folate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|upregulation of N5,10-methylenetetrahydrofolate reductase activity|up-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|positive regulation of MetF|positive regulation of methylenetetrahydrofolate reductase [NAD(P)H]|activation of 5,10-CH(2)-H(4)folate reductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|up-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up regulation of N5,N10-methylenetetrahydrofolate reductase activity|up-regulation of methylenetetrahydrofolate reductase (NADPH2)|upregulation of MetF|activation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|up-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|activation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|up regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|activation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up-regulation of N5,10-methylenetetrahydrofolate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|positive regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|activation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|up regulation of MetF|up-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|activation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|upregulation of N5,N10-methylenetetrahydrofolate reductase activity|positive regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up regulation of 5,10-CH2-H4folate reductase activity|upregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|upregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|up-regulation of MetF|positive regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|upregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|activation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|upregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of MetF|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|upregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|activation of N5,10-methylenetetrahydrofolate reductase activity|up regulation of methylenetetrahydrofolate reductase [NAD(P)H]|up-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity						rph	2015-02-05T13:26:33Z						biological_process											owl:Class	
GO:1903247	biolink:NamedThing	obsolete positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	OBSOLETE. Any process that activates or increases the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.	got7fsn_ti	up regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|positive regulation of If activation by beta-adrenergic receptor signaling pathway|upregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|activation of activation of funny current by beta-adrenergic receptor signaling pathway|upregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|positive regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|upregulation of If activation by beta-adrenergic receptor signaling pathway|positive regulation of activation of funny current by beta-adrenergic receptor signaling pathway|positive regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of If activation by beta-adrenergic receptor signaling pathway|up-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|activation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up regulation of activation of funny current by beta-adrenergic receptor signaling pathway|activation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|up-regulation of activation of funny current by beta-adrenergic receptor signaling pathway|up-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|up-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|up-regulation of If activation by beta-adrenergic receptor signaling pathway|up regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of activation of funny current by beta-adrenergic receptor signaling pathway|upregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|up-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|positive regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|positive regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up regulation of If activation by beta-adrenergic receptor signaling pathway|activation of adrenergic receptor signalling pathway involved in positive regulation of heart rate	https://github.com/geneontology/go-ontology/issues/14733			This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		rl	2014-08-04T11:54:06Z		True				biological_process											owl:Class	
GO:1904056	biolink:NamedThing	positive regulation of cholangiocyte proliferation	Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation.	got7fsn_ti	upregulation of hepatoblast proliferation|up-regulation of cholangiocyte proliferation|activation of cholangiocyte proliferation|positive regulation of hepatoblast proliferation|up regulation of hepatoblast proliferation|upregulation of cholangiocyte proliferation|up-regulation of hepatoblast proliferation|up regulation of cholangiocyte proliferation|activation of hepatoblast proliferation						sl	2015-03-18T17:56:26Z						biological_process											owl:Class	
GO:0016566	biolink:NamedThing	obsolete specific transcriptional repressor activity	OBSOLETE. Any activity that stops or downregulates transcription of specific genes or sets of genes.	got7fsn_ti	specific transcriptional repressor activity				This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001227|GO:0001217|GO:0045892				True				molecular_function											owl:Class	
GO:1900134	biolink:NamedThing	negative regulation of renin secretion into blood stream	Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream.	got7fsn_ti	downregulation of renin release into blood stream|inhibition of renin secretion into blood stream|negative regulation of renin release into blood stream|downregulation of renin secretion into blood stream|down regulation of renin secretion into blood stream|inhibition of renin release into blood stream|down-regulation of renin secretion into blood stream|down-regulation of renin release into blood stream|down regulation of renin release into blood stream						rph	2012-02-27T10:32:05Z						biological_process											owl:Class	
GO:0010883	biolink:NamedThing	regulation of lipid storage	Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.	got7fsn_ti	regulation of lipid sequestration													biological_process											owl:Class	
GO:1900694	biolink:NamedThing	positive regulation of (+)-kotanin biosynthetic process	Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process.	got7fsn_ti	positive regulation of (+)-kotanin formation|activation of (+)-kotanin synthesis|up-regulation of (+)-kotanin biosynthesis|up regulation of (+)-kotanin synthesis|up regulation of (+)-kotanin formation|upregulation of (+)-kotanin formation|up-regulation of (+)-kotanin synthesis|upregulation of (+)-kotanin biosynthetic process|up regulation of (+)-kotanin anabolism|up regulation of (+)-kotanin biosynthesis|positive regulation of (+)-kotanin synthesis|up regulation of (+)-kotanin biosynthetic process|upregulation of (+)-kotanin anabolism|positive regulation of (+)-kotanin biosynthesis|positive regulation of (+)-kotanin anabolism|up-regulation of (+)-kotanin anabolism|activation of (+)-kotanin biosynthesis|upregulation of (+)-kotanin synthesis|activation of (+)-kotanin biosynthetic process|up-regulation of (+)-kotanin formation|activation of (+)-kotanin formation|up-regulation of (+)-kotanin biosynthetic process|activation of (+)-kotanin anabolism|upregulation of (+)-kotanin biosynthesis						di	2012-05-22T04:53:33Z						biological_process											owl:Class	
GO:1900532	biolink:NamedThing	obsolete negative regulation of cell proliferation involved in cellular hyperosmotic response	OBSOLETE. Negative regulation of cell proliferation during cellular hyperosmotic response.	got7fsn_ti	negative regulation of cell proliferation of cellular hyperosmotic response|inhibition of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular hyperosmotic response|down regulation of cell proliferation of cellular hyperosmotic response|negative regulation of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular hypertonic response|downregulation of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular response to hypertonicity|negative regulation of cell proliferation of cellular response to hypertonicity|down-regulation of cell proliferation of cellular response to hypertonicity|negative regulation of cell proliferation of cellular hypertonic response|down-regulation of cell proliferation of cellular HOG response|down-regulation of cell proliferation of cellular hypertonic response|down regulation of cell proliferation of cellular HOG response|down regulation of cell proliferation of cellular response to hypertonicity|down regulation of cell proliferation of cellular hypertonic response|negative regulation of cell proliferation involved in cellular hyperosmotic response|inhibition of cell proliferation of cellular hypertonic response|down-regulation of cell proliferation of cellular hyperosmotic response|inhibition of cell proliferation of cellular response to hypertonicity|inhibition of cell proliferation of cellular hyperosmotic response				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2012-05-08T02:42:52Z		True				biological_process											owl:Class	
GO:0106188	biolink:NamedThing	obsolete translocase activity acting on hydrons linked the hydrolysis of a nucleoside triphosphate	OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a nucleoside triphosphate.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-07T18:09:07Z		True		EC:7.1.2.-		molecular_function											owl:Class	
GO:0110117	biolink:NamedThing	positive regulation of compound eye photoreceptor cell differentiation	Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.	got7fsn_ti							kmv	2018-07-16T18:13:28Z						biological_process											owl:Class	
GO:1903379	biolink:NamedThing	regulation of mitotic chromosome condensation	Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.	got7fsn_ti							al	2014-08-26T13:57:13Z						biological_process											owl:Class	
GO:0034157	biolink:NamedThing	positive regulation of toll-like receptor 7 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.	got7fsn_ti	positive regulation of TLR7 signaling pathway|positive regulation of toll-like receptor 7 signalling pathway													biological_process											owl:Class	
GO:1904395	biolink:NamedThing	positive regulation of skeletal muscle acetylcholine-gated channel clustering	Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.	got7fsn_ti	upregulation of skeletal muscle nicotinic acetylcholine receptor clustering|up-regulation of skeletal muscle nicotinic acetylcholine receptor clustering|activation of skeletal muscle acetylcholine-gated channel clustering|activation of skeletal muscle AChR clustering|up regulation of skeletal muscle nicotinic acetylcholine receptor clustering|positive regulation of skeletal muscle AChR clustering|up regulation of skeletal muscle acetylcholine-gated channel clustering|up-regulation of skeletal muscle acetylcholine-gated channel clustering|upregulation of skeletal muscle acetylcholine-gated channel clustering|up-regulation of skeletal muscle AChR clustering|positive regulation of skeletal muscle nicotinic acetylcholine receptor clustering|activation of skeletal muscle nicotinic acetylcholine receptor clustering|up regulation of skeletal muscle AChR clustering|upregulation of skeletal muscle AChR clustering						sl	2015-06-23T19:23:37Z						biological_process											owl:Class	
GO:0043581	biolink:NamedThing	obsolete mycelium development	OBSOLETE. The process whose specific outcome is the progression of the mycelium over time, from its formation to the mature structure. A mycelium consists of a mass of branching, thread-like hyphae.	got7fsn_ti					The reason for obsoletion is that the term is ambiguous. Three more clearly defined terms have been created that should be considered in its place.	GO:0097736|GO:0097738|GO:0097737				True				biological_process											owl:Class	
GO:0050939	biolink:NamedThing	regulation of early stripe melanocyte differentiation	Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation.	got7fsn_ti	regulation of early stripe melanophore differentiation													biological_process											owl:Class	
GO:0006209	biolink:NamedThing	cytosine catabolic process	The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.	got7fsn_ti	cytosine breakdown|cytosine catabolism|cytosine degradation													biological_process											owl:Class	
GO:0097171	biolink:NamedThing	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.	got7fsn_ti	ADP-L-glycero-beta-D-manno-heptose formation|ADP-L-glycero-beta-D-manno-heptose synthesis|ADP-L-glycero-beta-D-manno-heptose anabolism|ADP-L-glycero-beta-D-manno-heptose biosynthesis						pr	2011-10-03T09:15:03Z						biological_process											owl:Class	
GO:1903939	biolink:NamedThing	regulation of TORC2 signaling	Any process that modulates the frequency, rate or extent of TORC2 signaling.	got7fsn_ti	regulation of TORC2 signal transduction						al	2015-02-16T18:28:39Z						biological_process											owl:Class	
GO:1901054	biolink:NamedThing	sarcosine biosynthetic process	The chemical reactions and pathways resulting in the formation of sarcosine.	got7fsn_ti	sarcosine anabolism|sarcosine biosynthesis|sarcosine formation|sarcosine synthesis						yaf	2012-06-28T04:52:37Z						biological_process											owl:Class	
GO:1901131	biolink:NamedThing	kanamycin metabolic process	The chemical reactions and pathways involving kanamycin.	got7fsn_ti	kanamycin metabolism						yaf	2012-07-11T03:27:04Z						biological_process											owl:Class	
GO:0062029	biolink:NamedThing	positive regulation of stress granule assembly	Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.	got7fsn_ti							dph	2018-04-16T19:17:10Z						biological_process											owl:Class	
GO:1905357	biolink:NamedThing	negative regulation of snRNA pseudouridine synthesis	Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis.	got7fsn_ti	down-regulation of snRNA pseudouridine synthesis|downregulation of snRNA pseudouridine synthesis|inhibition of snRNA pseudouridine synthesis|down regulation of snRNA pseudouridine synthesis						se	2016-08-09T19:12:35Z						biological_process											owl:Class	
GO:1904462	biolink:NamedThing	ergosteryl 3-beta-D-glucoside catabolic process	The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside.	got7fsn_ti	ergosteryl 3-beta-D-glucoside breakdown|ergosteryl 3-beta-D-glucoside degradation|ergosteryl 3-beta-D-glucoside catabolism						mcc	2015-07-09T19:36:25Z						biological_process											owl:Class	
GO:0051388	biolink:NamedThing	positive regulation of neurotrophin TRK receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.	got7fsn_ti	upregulation of nerve growth factor receptor signaling pathway|positive regulation of NGF receptor signalling pathway|up-regulation of nerve growth factor receptor signaling pathway|positive regulation of nerve growth factor receptor signalling pathway|stimulation of nerve growth factor receptor signaling pathway|positive regulation of nerve growth factor receptor signaling pathway|up regulation of nerve growth factor receptor signaling pathway|activation of nerve growth factor receptor signaling pathway|positive regulation of NGF receptor signaling pathway													biological_process											owl:Class	
GO:0051170	biolink:NamedThing	import into nucleus	The directed movement of substances into the nucleus.	got7fsn_ti	substance nuclear import|single-organism nuclear import|single organism nuclear import|nuclear import						jl	2013-12-19T15:26:34Z			GO:1902593			biological_process											owl:Class	
GO:0015993	biolink:NamedThing	obsolete molecular hydrogen transport	OBSOLETE. The directed movement of molecular hydrogen (H2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti					The reason for obsoletion is that there molecular hydrogen (H2) diffuses passively through membranes (see https://www.researchgate.net/post/How_molecular_hydrogen_is_transported_through_the_cytoplasmic_membrane_of_Escherichia_coli).					True				biological_process											owl:Class	
GO:0002146	biolink:NamedThing	obsolete steroid hormone receptor import into nucleus	OBSOLETE. The directed movement of a steroid hormone receptor into the nucleus.	got7fsn_ti	steroid hormone receptor nuclear translocation				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0042306|GO:0006606	hjd	2009-07-09T02:34:42Z		True				biological_process											owl:Class	
dc:title	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
GO:0032306	biolink:NamedThing	regulation of prostaglandin secretion	Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	got7fsn_ti	regulation of prostacyclin secretion													biological_process											owl:Class	
GO:0045345	biolink:NamedThing	positive regulation of MHC class I biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.	got7fsn_ti	upregulation of MHC class I biosynthetic process|activation of MHC class I biosynthetic process|positive regulation of major histocompatibility complex class I biosynthetic process|positive regulation of MHC class I formation|stimulation of MHC class I biosynthetic process|positive regulation of MHC class I synthesis|positive regulation of MHC class I biosynthesis|positive regulation of major histocompatibility complex class I biosynthesis|positive regulation of MHC class I anabolism|up-regulation of MHC class I biosynthetic process|up regulation of MHC class I biosynthetic process													biological_process											owl:Class	
GO:0006670	biolink:NamedThing	sphingosine metabolic process	The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.	got7fsn_ti	(4E)-sphing-4-enine metabolic process|sphing-4-enine metabolism|sphing-4-enine metabolic process|sphingosine metabolism|(4E)-sphing-4-enine metabolism													biological_process											owl:Class	
GO:0071886	biolink:NamedThing	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding	Binding to the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug.	got7fsn_ti	1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane binding|(+/-)2-(4-iodo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine binding|4-iodo-2,5-dimethoxyphenylisopropylamine binding						mah	2010-09-14T12:29:36Z						molecular_function											owl:Class	
CHEBI:29669	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052116	biolink:NamedThing	obsolete chemotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	chemotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0004229	biolink:NamedThing	obsolete gelatinase B activity	OBSOLETE. Catalysis of the cleavage of gelatin types I and V and collagen types IV and V.	got7fsn_ti	collagenase IV|MMP 9|95 kDa type IV collagenase/gelatinase activity|macrophage gelatinase activity|matrix metalloproteinase 9 activity|gelatinase MMP 9|collagenase type IV|gelatinase B activity|92-kDa gelatinase activity|type IV collagen metalloproteinase|type V collagenase activity|MMP-9|92-kDa type IV collagenase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0005603	biolink:NamedThing	obsolete complement component C2 complex	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	complement component C2 complex				This term was made obsolete because prior to cleavage, complement component C2 is a single polypeptide rather than a complex, and after cleavage the products do not remain physically associated; there is thus no known biological entity corresponding to "complement C2 complex".					True				cellular_component											owl:Class	
GO:0098641	biolink:NamedThing	cadherin binding involved in cell-cell adhesion	Any cadherin binding that occurs as part of the process of cell-cell adhesion.	got7fsn_ti														molecular_function											owl:Class	
GO:1904047	biolink:NamedThing	S-adenosyl-L-methionine binding	Binding to S-adenosyl-L-methionine.	got7fsn_ti	radical SAM enzyme activity						hal	2015-03-17T10:32:16Z			GO:0070283	Reactome:R-HSA-947535		molecular_function											owl:Class	
GO:0045922	biolink:NamedThing	negative regulation of fatty acid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.	got7fsn_ti	downregulation of fatty acid metabolic process|down-regulation of fatty acid metabolic process|down regulation of fatty acid metabolic process|inhibition of fatty acid metabolic process|negative regulation of fatty acid metabolism													biological_process											owl:Class	
GO:0001317	biolink:NamedThing	obsolete accumulation of oxidatively modified proteins involved in replicative cell aging	OBSOLETE. Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.	got7fsn_ti	accumulation of oxidatively modified proteins during replicative cell aging|accumulation of oxidatively modified proteins during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0075193	biolink:NamedThing	regulation of haustorium mother cell formation	Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of haustorium mother cell formation on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0051245	biolink:NamedThing	negative regulation of cellular defense response	Any process that stops, prevents, or reduces the rate of the cellular defense response.	got7fsn_ti	down-regulation of cellular defense response|negative regulation of cellular defence response|inhibition of cellular defense response|down regulation of cellular defense response|downregulation of cellular defense response													biological_process											owl:Class	
GO:0009375	biolink:NamedThing	ferredoxin hydrogenase complex	An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances.	got7fsn_ti	hydrogenase complex													cellular_component											owl:Class	
GO:1903358	biolink:NamedThing	regulation of Golgi organization	Any process that modulates the frequency, rate or extent of Golgi organization.	got7fsn_ti	regulation of Golgi organization and biogenesis|regulation of Golgi organisation						als	2014-08-21T10:22:22Z						biological_process											owl:Class	
GO:1903849	biolink:NamedThing	positive regulation of aorta morphogenesis	Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.	got7fsn_ti	up regulation of aorta morphogenesis|up-regulation of aorta morphogenesis|activation of aorta morphogenesis|upregulation of aorta morphogenesis						rph	2015-01-23T14:01:09Z						biological_process											owl:Class	
GO:0051988	biolink:NamedThing	regulation of attachment of spindle microtubules to kinetochore	Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.	got7fsn_ti	regulation of kinetochore-microtubule attachment													biological_process											owl:Class	
GO:0071844	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005206	biolink:NamedThing	obsolete heparin sulfate proteoglycan	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	heparin sulphate proteoglycan|heparin sulfate proteoglycan				This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0000991	biolink:NamedThing	obsolete transcription factor activity, core RNA polymerase II binding	OBSOLETE. Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	core RNA polymerase II binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0140110|GO:0000993	krc	2010-08-10T05:03:45Z		True				molecular_function											owl:Class	
GO:0006215	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902545	biolink:NamedThing	negative regulation of DNA N-glycosylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA N-glycosylase activity.	got7fsn_ti	down-regulation of DNA N-glycosylase activity|inhibition of DNA N-glycosylase activity|down regulation of DNA glycosylase activity|negative regulation of endonuclease VIII activity|downregulation of endonuclease VIII activity|downregulation of DNA glycosylase activity|inhibition of endonuclease VIII activity|inhibition of DNA glycosylase activity|down-regulation of endonuclease VIII activity|down regulation of endonuclease VIII activity|down regulation of DNA N-glycosylase activity|downregulation of DNA N-glycosylase activity|negative regulation of DNA glycosylase activity|down-regulation of DNA glycosylase activity						rph	2013-12-04T14:18:03Z						biological_process											owl:Class	
GO:0016103	biolink:NamedThing	diterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.	got7fsn_ti	diterpenoid catabolism|diterpene catabolism|diterpene catabolic process|diterpenoid breakdown|diterpenoid degradation													biological_process											owl:Class	
GO:0034489	biolink:NamedThing	neutral amino acid transmembrane export from vacuole	The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
GO:1904280	biolink:NamedThing	negative regulation of transcription by RNA polymerase V	Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V.	got7fsn_ti	negative regulation of transcription from RNA polymerase V promoter|downregulation of transcription from RNA polymerase V promoter|downregulation of transcription from RNA pol V promoter|inhibition of transcription from RNA pol V promoter|negative regulation of transcription from RNA pol V promoter|down regulation of transcription from RNA pol V promoter|down-regulation of transcription from RNA pol V promoter|down regulation of transcription from RNA polymerase V promoter|down-regulation of transcription from RNA polymerase V promoter|inhibition of transcription from RNA polymerase V promoter						tb	2015-06-03T22:01:54Z						biological_process											owl:Class	
GO:2001240	biolink:NamedThing	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.	got7fsn_ti	negative regulation of dependence receptor signaling pathway|negative regulation of extrinsic apoptotic signalling pathway in absence of ligand|negative regulation of extrinsic apoptosis in absence of ligand						pr	2011-11-24T01:33:25Z						biological_process											owl:Class	
GO:0032205	biolink:NamedThing	negative regulation of telomere maintenance	Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.	got7fsn_ti	down regulation of telomere maintenance|down-regulation of telomere maintenance|inhibition of telomere maintenance|downregulation of telomere maintenance													biological_process											owl:Class	
GO:1905301	biolink:NamedThing	regulation of macropinocytosis	Any process that modulates the frequency, rate or extent of macropinocytosis.	got7fsn_ti	regulation of clathrin-independent pinocytosis						pad	2016-07-04T14:16:32Z						biological_process											owl:Class	
GO:0052395	biolink:NamedThing	obsolete induction by organism of defense-related symbiont nitric oxide production	OBSOLETE. The activation by an organism of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of defense-related symbiont nitric oxide production|activation by organism of defense-related symbiont NO production|induction by organism of defense-related symbiont NO production|activation by organism of defense-related symbiont nitric acid production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0032962	biolink:NamedThing	positive regulation of inositol trisphosphate biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.	got7fsn_ti	positive regulation of inositol trisphosphate formation|positive regulation of myo-inositol trisphosphate biosynthesis|positive regulation of IP3 biosynthesis|positive regulation of inositol trisphosphate biosynthesis|positive regulation of IP3 biosynthetic process|positive regulation of inositol trisphosphate anabolism|positive regulation of inositol trisphosphate synthesis|positive regulation of myo-inositol trisphosphate biosynthetic process													biological_process											owl:Class	
GO:0060704	biolink:NamedThing	acinar cell differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.	got7fsn_ti							dph	2009-06-09T09:32:46Z						biological_process											owl:Class	
GO:0035980	biolink:NamedThing	obsolete invasive growth in response to nitrogen limitation	OBSOLETE. The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen.	got7fsn_ti	invasive growth in response to nitrogen limitation				This term was made obsolete because the GO term 'pseudohyphal growth ; GO:0007124' describes growth under nitrogen-limiting conditions.	GO:0007124	bf	2011-08-22T01:20:39Z		True				biological_process											owl:Class	
GO:1905483	biolink:NamedThing	regulation of motor neuron migration	Any process that modulates the frequency, rate or extent of motor neuron migration.	got7fsn_ti							hbye	2016-09-23T12:49:54Z						biological_process											owl:Class	
GO:1900902	biolink:NamedThing	regulation of hexadecanal biosynthetic process	Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process.	got7fsn_ti	regulation of palmitaldehyde biosynthesis|regulation of hexadecanal formation|regulation of hexadecanal anabolism|regulation of hexadecanal biosynthesis|regulation of hexadecanal synthesis|regulation of palmitaldehyde biosynthetic process						tt	2012-06-13T03:33:10Z						biological_process											owl:Class	
GO:1902498	biolink:NamedThing	regulation of protein autoubiquitination	Any process that modulates the frequency, rate or extent of protein autoubiquitination.	got7fsn_ti	regulation of protein self-ubiquitinylation|regulation of protein auto-ubiquitinylation|regulation of protein autoubiquitinylation|regulation of protein self-ubiquitination|regulation of protein auto-ubiquitination						rb	2013-11-13T21:03:28Z						biological_process											owl:Class	
GO:1903541	biolink:NamedThing	regulation of exosomal secretion	Any process that modulates the frequency, rate or extent of exosomal secretion.	got7fsn_ti	regulation of exosomal protein secretion|regulation of extracellular vesicular exosome secretion|regulation of exosomal secretory pathway|regulation of secretion of exosome						pga	2014-10-14T11:38:52Z						biological_process											owl:Class	
GO:0002603	biolink:NamedThing	positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.	got7fsn_ti	positive regulation of polysaccharide antigen processing and presentation via MHC class II|stimulation of antigen processing and presentation of polysaccharide antigen via MHC class II|up regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|activation of antigen processing and presentation of polysaccharide antigen via MHC class II|up-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|upregulation of antigen processing and presentation of polysaccharide antigen via MHC class II													biological_process											owl:Class	
GO:0045976	biolink:NamedThing	negative regulation of mitotic cell cycle, embryonic	Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle.	got7fsn_ti	negative regulation of embryonic mitotic cell cycle|down regulation of progression through embryonic mitotic cell cycle|inhibition of progression through embryonic mitotic cell cycle|negative regulation of embryonic mitotic cell cycle progression|down-regulation of progression through embryonic mitotic cell cycle|negative regulation of progression through embryonic mitotic cell cycle|downregulation of progression through embryonic mitotic cell cycle													biological_process											owl:Class	
GO:1904519	biolink:NamedThing	protein localization to microtubule minus-end	A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end.	got7fsn_ti	protein localisation in microtubule minus-end|protein localization in microtubule minus-end|protein localisation to microtubule minus-end						mah	2015-07-29T14:46:11Z						biological_process											owl:Class	
GO:2001076	biolink:NamedThing	positive regulation of metanephric ureteric bud development	Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development.	got7fsn_ti							yaf	2011-09-14T01:11:15Z						biological_process											owl:Class	
GO:2000584	biolink:NamedThing	negative regulation of platelet-derived growth factor receptor-alpha signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.	got7fsn_ti	negative regulation of alphaPDGF receptor signaling pathway|negative regulation of platelet-derived growth factor receptor-alpha signalling pathway|negative regulation of PDGFR-alpha signaling pathway|negative regulation of PDGF receptor-alpha signaling pathway						bf	2011-04-07T03:26:31Z						biological_process											owl:Class	
GO:0060236	biolink:NamedThing	regulation of mitotic spindle organization	Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.	got7fsn_ti	regulation of mitotic spindle organization and biogenesis|regulation of mitotic spindle organisation													biological_process											owl:Class	
GO:0046457	biolink:NamedThing	prostanoid biosynthetic process	The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure.	got7fsn_ti	prostanoid anabolism|prostanoid biosynthesis|prostanoid formation|prostanoid synthesis											Wikipedia:Prostanoid#Biosynthesis		biological_process											owl:Class	
GO:1904983	biolink:NamedThing	glycine import into mitochondrion	The process in which glycine is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti	transmembrane glycine transport from cytosol to mitochondrion						vw	2016-02-28T21:53:44Z						biological_process											owl:Class	
GO:0032220	biolink:NamedThing	plasma membrane fusion involved in cytogamy	The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy.	got7fsn_ti	plasma membrane organization involved in conjugation with cellular fusion|plasma membrane fusion during cytogamy	https://github.com/geneontology/go-ontology/issues/16258					mah	2009-08-20T02:24:56Z			GO:0070872			biological_process											owl:Class	
GO:2001037	biolink:NamedThing	positive regulation of tongue muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.	got7fsn_ti							yaf	2011-08-24T11:10:22Z						biological_process											owl:Class	
GO:0004327	biolink:NamedThing	obsolete formaldehyde dehydrogenase (glutathione) activity	OBSOLETE. Catalysis of the reaction: formaldehyde + glutathione + NAD+ = S-formylglutathione + NADH + H+.	got7fsn_ti	formaldehyde dehydrogenase (glutathione) activity				This term was made obsolete because it was derived from an EC entry (1.2.1.1) that has since been split into two entries.	GO:0051907|GO:0051903				True				molecular_function											owl:Class	
GO:0003715	biolink:NamedThing	obsolete transcription termination factor activity	OBSOLETE. Any activity that brings about termination of transcription.	got7fsn_ti	transcriptional termination factor activity|transcription termination factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006353				True				molecular_function											owl:Class	
GO:1990982	biolink:NamedThing	obsolete Immune memory response	OBSOLETE. The immune response against a previously encountered antigen being quicker and quantitatively better compared with the primary response.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sp	2016-09-01T10:57:56Z		True				biological_process											owl:Class	
GO:0045672	biolink:NamedThing	positive regulation of osteoclast differentiation	Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.	got7fsn_ti	activation of osteoclast differentiation|stimulation of osteoclast differentiation|upregulation of osteoclast differentiation|up-regulation of osteoclast differentiation|up regulation of osteoclast differentiation													biological_process											owl:Class	
GO:1905082	biolink:NamedThing	regulation of mitochondrial translational elongation	Any process that modulates the frequency, rate or extent of mitochondrial translational elongation.	got7fsn_ti	regulation of mitochondrial translation elongation						hjd	2016-03-25T17:37:03Z						biological_process											owl:Class	
GO:1903542	biolink:NamedThing	negative regulation of exosomal secretion	Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion.	got7fsn_ti	downregulation of exosomal protein secretion|down regulation of exosomal protein secretion|down-regulation of extracellular vesicular exosome secretion|negative regulation of exosomal secretory pathway|down-regulation of secretion of exosome|inhibition of extracellular vesicular exosome secretion|down regulation of secretion of exosome|negative regulation of exosomal protein secretion|inhibition of exosomal protein secretion|down-regulation of exosomal secretory pathway|inhibition of exosomal secretory pathway|inhibition of secretion of exosome|downregulation of exosomal secretion|down-regulation of exosomal protein secretion|downregulation of secretion of exosome|down regulation of exosomal secretion|negative regulation of secretion of exosome|downregulation of extracellular vesicular exosome secretion|downregulation of exosomal secretory pathway|down regulation of extracellular vesicular exosome secretion|negative regulation of extracellular vesicular exosome secretion|inhibition of exosomal secretion|down-regulation of exosomal secretion|down regulation of exosomal secretory pathway						pga	2014-10-14T11:39:02Z						biological_process											owl:Class	
GO:0070406	biolink:NamedThing	glutamine binding	Binding to glutamine, 2,5-diamino-5-oxopentanoic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0009396	biolink:NamedThing	folic acid-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.	got7fsn_ti	vitamin B9 and derivative biosynthesis|folate and derivative biosynthetic process|folic acid-containing compound synthesis|folic acid and derivative biosynthesis|folate-containing compound biosynthesis|folic acid and derivative biosynthetic process|folic acid-containing compound anabolism|folic acid-containing compound biosynthesis|vitamin M and derivative biosynthesis|vitamin B9 and derivative biosynthetic process|folate and derivative biosynthesis|folic acid-containing compound formation|vitamin M and derivative biosynthetic process|folate-containing compound biosynthetic process													biological_process											owl:Class	
GO:1902839	biolink:NamedThing	negative regulation of nuclear migration along microtubule	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.	got7fsn_ti	inhibition of transport of nucleus by microtubules|negative regulation of transport of nucleus, microtubule-mediated|inhibition of microtubule cytoskeleton-dependent nucleus positioning|negative regulation of microtubule-dependent nuclear positioning|down-regulation of microtubule-mediated nuclear migration|downregulation of microtubule cytoskeleton-dependent nuclear positioning|inhibition of nuclear migration, microtubule-mediated|down regulation of nuclear migration, microtubule-mediated|downregulation of microtubule-dependent nucleus positioning|down regulation of microtubule cytoskeleton-dependent nuclear positioning|downregulation of nuclear migration, microtubule-mediated|down-regulation of microtubule-dependent nucleus positioning|inhibition of nuclear migration along microtubule|down-regulation of transport of nucleus by microtubules|downregulation of microtubule cytoskeleton-dependent nucleus positioning|down-regulation of microtubule-dependent nuclear positioning|down regulation of microtubule-dependent nuclear positioning|down-regulation of nuclear migration along microtubule|inhibition of microtubule-dependent nucleus positioning|down regulation of transport of nucleus, microtubule-mediated|down-regulation of transport of nucleus, microtubule-mediated|down-regulation of microtubule cytoskeleton-dependent nuclear positioning|down-regulation of microtubule cytoskeleton-dependent nucleus positioning|downregulation of transport of nucleus by microtubules|downregulation of transport of nucleus, microtubule-mediated|inhibition of transport of nucleus, microtubule-mediated|down regulation of microtubule cytoskeleton-dependent nucleus positioning|inhibition of microtubule-dependent nuclear positioning|negative regulation of microtubule-dependent nucleus positioning|negative regulation of microtubule-mediated nuclear migration|inhibition of microtubule cytoskeleton-dependent nuclear positioning|negative regulation of microtubule cytoskeleton-dependent nuclear positioning|downregulation of microtubule-dependent nuclear positioning|down-regulation of nuclear migration, microtubule-mediated|negative regulation of nuclear migration, microtubule-mediated|down regulation of microtubule-mediated nuclear migration|downregulation of nuclear migration along microtubule|inhibition of microtubule-mediated nuclear migration|down regulation of nuclear migration along microtubule|down regulation of microtubule-dependent nucleus positioning|downregulation of microtubule-mediated nuclear migration|negative regulation of microtubule cytoskeleton-dependent nucleus positioning|down regulation of transport of nucleus by microtubules|negative regulation of transport of nucleus by microtubules						vw	2014-04-01T13:50:29Z						biological_process											owl:Class	
GO:1904796	biolink:NamedThing	regulation of core promoter binding	Any process that modulates the frequency, rate or extent of core promoter binding.	got7fsn_ti							nc	2015-11-09T12:32:23Z						biological_process											owl:Class	
GO:0001310	biolink:NamedThing	obsolete extrachromosomal rDNA circle accumulation involved in replicative cell aging	OBSOLETE. Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.	got7fsn_ti	extrachromosomal rDNA circle accumulation during replicative cell aging|extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|extrachromosomal rDNA circle accumulation during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0046580	biolink:NamedThing	negative regulation of Ras protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.	got7fsn_ti	inhibition of Ras protein signal transduction|down-regulation of Ras protein signal transduction|down regulation of Ras protein signal transduction|downregulation of Ras protein signal transduction													biological_process											owl:Class	
GO:0048146	biolink:NamedThing	positive regulation of fibroblast proliferation	Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.	got7fsn_ti	activation of fibroblast proliferation|up regulation of fibroblast proliferation|upregulation of fibroblast proliferation|stimulation of fibroblast proliferation|up-regulation of fibroblast proliferation													biological_process											owl:Class	
GO:1902064	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in spermatogenesis	Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis.	got7fsn_ti	regulation of gene-specific transcription from RNA polymerase II promoter involved in spermatogenesis|regulation of transcription from RNA polymerase II promoter, global involved in spermatogenesis|regulation of transcription from RNA polymerase II promoter, global involved in generation of spermatozoa|regulation of transcription from Pol II promoter involved in spermatogenesis|global transcription regulation from Pol II promoter involved in generation of spermatozoa|regulation of global transcription from Pol II promoter involved in generation of spermatozoa|regulation of gene-specific transcription from RNA polymerase II promoter involved in generation of spermatozoa|regulation of transcription from RNA polymerase II promoter involved in generation of spermatozoa|regulation of global transcription from Pol II promoter involved in spermatogenesis|global transcription regulation from Pol II promoter involved in spermatogenesis|regulation of transcription from Pol II promoter involved in generation of spermatozoa						kmv	2013-04-16T20:27:18Z						biological_process											owl:Class	
GO:0042290	biolink:NamedThing	obsolete URM1 hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	URM1 hydrolase activity				This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True				molecular_function											owl:Class	
GO:1901366	biolink:NamedThing	funalenone biosynthetic process	The chemical reactions and pathways resulting in the formation of funalenone.	got7fsn_ti	funalenone synthesis|funalenone formation|funalenone anabolism|funalenone biosynthesis						di	2012-09-17T18:25:47Z						biological_process											owl:Class	
GO:0061066	biolink:NamedThing	positive regulation of dauer larval development	Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.	got7fsn_ti							dph	2010-03-11T01:09:11Z						biological_process											owl:Class	
GO:0090073	biolink:NamedThing	positive regulation of protein homodimerization activity	Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.	got7fsn_ti							tb	2009-09-11T11:15:40Z						biological_process											owl:Class	
GO:0010751	biolink:NamedThing	negative regulation of nitric oxide mediated signal transduction	Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).	got7fsn_ti	negative regulation of nitric oxide-mediated signal transduction													biological_process											owl:Class	
GO:1990652	biolink:NamedThing	obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage.	got7fsn_ti	positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-02-23T11:25:51Z		True				biological_process											owl:Class	
GO:1902398	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008246	biolink:NamedThing	obsolete electron transfer flavoprotein	OBSOLETE. Works in conjunction with acyl-CoA dehydrogenase to catalyze the oxidation of CoA and reduce ubiquinone. Part of the mitochondrial electron transport system.	got7fsn_ti	ETF|electron transfer flavoprotein			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:0098660	biolink:NamedThing	inorganic ion transmembrane transport	The process in which an inorganic ion is transported across a membrane.	got7fsn_ti	inorganic ion membrane transport|transmembrane inorganic ion transport				Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:2000198	biolink:NamedThing	negative regulation of ribonucleoprotein complex localization	Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization.	got7fsn_ti	negative regulation of RNP localization|negative regulation of cellular ribonucleoprotein complex localization|negative regulation of establishment and maintenance of ribonucleoprotein complex localization|negative regulation of ribonucleoprotein complex localisation						mah	2010-10-26T10:35:52Z						biological_process											owl:Class	
GO:1900847	biolink:NamedThing	negative regulation of naphtho-gamma-pyrone biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.	got7fsn_ti	down regulation of naphtho-gamma-pyrone biosynthetic process|downregulation of naphtho-gamma-pyrone biosynthetic process|down-regulation of naphtho-gamma-pyrone biosynthetic process|inhibition of naphtho-gamma-pyrone biosynthetic process						di	2012-06-07T09:43:03Z						biological_process											owl:Class	
GO:0046272	biolink:NamedThing	stilbene catabolic process	The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.	got7fsn_ti	stilbene degradation|stilbene breakdown|stilbene catabolism													biological_process											owl:Class	
GO:0031655	biolink:NamedThing	negative regulation of heat dissipation	Any process that stops, prevents, or reduces the rate or extent of heat dissipation.	got7fsn_ti	down-regulation of heat dissipation|inhibition of heat dissipation|down regulation of heat dissipation|downregulation of heat dissipation													biological_process											owl:Class	
GO:1902840	biolink:NamedThing	positive regulation of nuclear migration along microtubule	Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.	got7fsn_ti	up-regulation of nuclear migration along microtubule|positive regulation of microtubule cytoskeleton-dependent nuclear positioning|up-regulation of microtubule-dependent nuclear positioning|activation of microtubule cytoskeleton-dependent nucleus positioning|activation of microtubule-dependent nucleus positioning|positive regulation of nuclear migration, microtubule-mediated|positive regulation of microtubule cytoskeleton-dependent nucleus positioning|up-regulation of microtubule cytoskeleton-dependent nuclear positioning|positive regulation of microtubule-dependent nucleus positioning|activation of microtubule cytoskeleton-dependent nuclear positioning|upregulation of microtubule cytoskeleton-dependent nuclear positioning|up regulation of transport of nucleus by microtubules|up regulation of transport of nucleus, microtubule-mediated|upregulation of nuclear migration, microtubule-mediated|upregulation of microtubule cytoskeleton-dependent nucleus positioning|positive regulation of microtubule-mediated nuclear migration|up regulation of microtubule cytoskeleton-dependent nuclear positioning|up-regulation of microtubule-dependent nucleus positioning|activation of nuclear migration, microtubule-mediated|up regulation of nuclear migration along microtubule|upregulation of transport of nucleus by microtubules|up regulation of microtubule-dependent nuclear positioning|positive regulation of microtubule-dependent nuclear positioning|upregulation of microtubule-dependent nuclear positioning|up-regulation of microtubule cytoskeleton-dependent nucleus positioning|up regulation of microtubule-dependent nucleus positioning|activation of transport of nucleus, microtubule-mediated|positive regulation of transport of nucleus, microtubule-mediated|upregulation of transport of nucleus, microtubule-mediated|up regulation of microtubule cytoskeleton-dependent nucleus positioning|up-regulation of transport of nucleus by microtubules|up-regulation of transport of nucleus, microtubule-mediated|up regulation of microtubule-mediated nuclear migration|upregulation of nuclear migration along microtubule|up regulation of nuclear migration, microtubule-mediated|activation of nuclear migration along microtubule|upregulation of microtubule-mediated nuclear migration|activation of microtubule-dependent nuclear positioning|upregulation of microtubule-dependent nucleus positioning|activation of microtubule-mediated nuclear migration|activation of transport of nucleus by microtubules|up-regulation of microtubule-mediated nuclear migration|positive regulation of transport of nucleus by microtubules|up-regulation of nuclear migration, microtubule-mediated						vw	2014-04-01T13:50:35Z						biological_process											owl:Class	
GO:0052054	biolink:NamedThing	obsolete negative regulation by symbiont of host peptidase activity	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition by symbiont of host protease activity|inhibition of host protease activity|downregulation by symbiont of host protease activity|down regulation by symbiont of host protease activity|down-regulation by symbiont of host protease activity|negative regulation by symbiont of host protease activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0052530	biolink:NamedThing	obsolete positive regulation by organism of symbiont resistance gene-dependent defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of symbiont gene-for-gene resistance|positive regulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|positive regulation by organism of symbiont resistance gene-dependent defense response|positive regulation by organism of defense response in symbiont by specific elicitors				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1900831	biolink:NamedThing	D-leucine metabolic process	The chemical reactions and pathways involving D-leucine.	got7fsn_ti	D-leucine metabolism						se	2012-06-06T09:37:17Z						biological_process											owl:Class	
GO:0009397	biolink:NamedThing	folic acid-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives.	got7fsn_ti	vitamin B9 and derivative catabolism|folate and derivative catabolic process|vitamin M and derivative catabolism|folic acid-containing compound degradation|folate-containing compound catabolism|vitamin M and derivative catabolic process|folate and derivative catabolism|folic acid-containing compound breakdown|folate-containing compound catabolic process|folic acid-containing compound catabolism|folic acid and derivative catabolism|folic acid and derivative catabolic process|vitamin B9 and derivative catabolic process													biological_process											owl:Class	
GO:0046242	biolink:NamedThing	obsolete o-xylene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	o-xylene formation|o-xylene synthesis|o-xylene anabolism|ortho-xylene biosynthetic process|o-xylene biosynthesis|o-xylene biosynthetic process|ortho-xylene biosynthesis			GO:0018950	This term was made obsolete because o-xylene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1903898	biolink:NamedThing	negative regulation of PERK-mediated unfolded protein response	Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.	got7fsn_ti	inhibition of UPR signaling by PERK stress sensor|down regulation of PERK branch of UPR|down-regulation of PERK-mediated unfolded protein response|negative regulation of PERK branch of UPR|down regulation of PERK-mediated unfolded protein response|negative regulation of EIF2AK3-mediated unfolded protein response|downregulation of UPR signaling by PERK stress sensor|downregulation of PERK-mediated unfolded protein response|inhibition of PERK branch of UPR|down-regulation of PERK signaling in response to endoplasmic reticulum stress|down-regulation of PKR-like ER kinase signal transduction|down-regulation of PERK branch of UPR|down-regulation of endoplasmic reticulum unfolded protein response; PERK signaling|down-regulation of UPR signaling by PERK stress sensor|downregulation of PERK branch of UPR|downregulation of PERK signaling in response to endoplasmic reticulum stress|down regulation of PERK signaling in response to endoplasmic reticulum stress|downregulation of PKR-like ER kinase signal transduction|negative regulation of UPR signaling by PERK stress sensor|negative regulation of PKR-like ER kinase signal transduction|down regulation of UPR signaling by PERK stress sensor|down regulation of PKR-like ER kinase signal transduction|downregulation of endoplasmic reticulum unfolded protein response; PERK signaling|down regulation of endoplasmic reticulum unfolded protein response; PERK signaling|inhibition of endoplasmic reticulum unfolded protein response; PERK signaling|negative regulation of PERK signaling in response to endoplasmic reticulum stress|inhibition of PERK signaling in response to endoplasmic reticulum stress|inhibition of PKR-like ER kinase signal transduction|negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling|inhibition of PERK-mediated unfolded protein response						bf	2015-02-09T10:18:23Z						biological_process											owl:Class	
GO:1902230	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.	got7fsn_ti	down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage|down regulation of DNA damage response, signal transduction resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to DNA damage|downregulation of DNA damage response, signal transduction resulting in induction of apoptosis|inhibition of DNA damage response, signal transduction resulting in induction of apoptosis|negative regulation of DNA damage response, signal transduction resulting in induction of apoptosis|down-regulation of DNA damage response, signal transduction resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway in response to DNA damage|down regulation of intrinsic apoptotic signaling pathway in response to DNA damage						rl	2013-06-14T09:39:58Z						biological_process											owl:Class	
GO:1905455	biolink:NamedThing	positive regulation of myeloid progenitor cell differentiation	Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation.	got7fsn_ti	up regulation of myeloid progenitor cell differentiation|activation of myeloid progenitor cell differentiation|upregulation of myeloid progenitor cell differentiation|up-regulation of myeloid progenitor cell differentiation						rz	2016-09-16T12:32:33Z						biological_process											owl:Class	
GO:0021920	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of neuronal precursors to association neurons in the dorsal spinal cord.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0021519				True				biological_process											owl:Class	
GO:1900180	biolink:NamedThing	regulation of protein localization to nucleus	Any process that modulates the frequency, rate or extent of protein localization to nucleus.	got7fsn_ti	regulation of protein localisation to nucleus|regulation of protein localization in cell nucleus|regulation of protein localization in nucleus						bf	2012-03-12T01:23:44Z						biological_process											owl:Class	
GO:0098663	biolink:NamedThing	obsolete transmembrane transporter activity involved in import into cell	OBSOLETE. Any transmembrane transporter activity that is involved in importing some substance into a cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14322			The reason for obsoletion is that this terms partly represents the process "import into cell".					True				molecular_function											owl:Class	
GO:1901838	biolink:NamedThing	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.	got7fsn_ti	activation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|up regulation of transcription of nuclear rRNA large Pol I transcript|up-regulation of transcription of nuclear rRNA large Pol I transcript|up regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|up-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|activation of transcription of nuclear rRNA large Pol I transcript|positive regulation of transcription of nuclear rRNA large Pol I transcript|upregulation of transcription of nuclear rRNA large Pol I transcript|positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|upregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter						sart	2013-01-23T10:16:36Z						biological_process											owl:Class	
GO:0015007	biolink:NamedThing	obsolete electron carrier, chlorophyll electron transport system	OBSOLETE. A molecular entity that serves as an electron acceptor and electron donor in a chlorophyll electron transport system.	got7fsn_ti	chlorophyll electron carrier|electron carrier, chlorophyll electron transport system				This term was made obsolete because it contains both process and function information.	GO:0009055|GO:0009767				True				molecular_function											owl:Class	
GO:0110124	biolink:NamedThing	positive regulation of myotube cell migration	Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.	got7fsn_ti							kmv	2018-08-22T21:09:38Z						biological_process											owl:Class	
GO:2000572	biolink:NamedThing	positive regulation of interleukin-4-dependent isotype switching to IgE isotypes	Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.	got7fsn_ti	positive regulation of IL-4-dependent isotype switching to IgE isotypes						ebc	2011-04-03T09:20:18Z						biological_process											owl:Class	
GO:0045192	biolink:NamedThing	obsolete low-density lipoprotein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of low-density lipoproteins, also known as beta lipoproteins, one of the classes of lipoproteins found in the bloodstream of animals, acting as a carrier for cholesterol and fats.	got7fsn_ti	LDL catabolism|low-density lipoprotein breakdown|low-density lipoprotein catabolism|low-density lipoprotein degradation|low-density lipoprotein catabolic process|LDL catabolic process				This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds.					True				biological_process											owl:Class	
GO:0004193	biolink:NamedThing	obsolete cathepsin E activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin D, but slightly broader specificity.	got7fsn_ti	cathepsin D-like acid proteinase activity|cathepsin E activity|cathepsin E-like acid proteinase activity|erythrocyte membrane aspartic proteinase activity|SMP|slow-moving proteinase activity|cathepsin D-type proteinase activity|EMAP|non-pepsin proteinase activity			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0009075	biolink:NamedThing	obsolete histidine family amino acid metabolic process	OBSOLETE. The chemical reactions and pathways involving amino acids of the histidine family.	got7fsn_ti	histidine family amino acid metabolic process|histidine family amino acid metabolism			GO:0006547	This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family.					True				biological_process											owl:Class	
GO:0006654	biolink:NamedThing	phosphatidic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.	got7fsn_ti	phosphatidic acid biosynthesis|phosphatidic acid formation|phosphatidic acid synthesis|phosphatidic acid anabolism													biological_process											owl:Class	
GO:0061278	biolink:NamedThing	epithelial cell migration involved in mesonephric nephron tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.	got7fsn_ti							dph	2010-09-02T01:18:53Z						biological_process											owl:Class	
GO:1900496	biolink:NamedThing	positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA	Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.	got7fsn_ti	up regulation of butyryl-CoA biosynthetic process from acetyl-CoA|up regulation of butyryl-CoA biosynthesis from acetyl-CoA|upregulation of butyryl-CoA biosynthetic process from acetyl-CoA|upregulation of butyryl-CoA biosynthesis from acetyl-CoA|activation of butyryl-CoA biosynthesis from acetyl-CoA|up-regulation of butyryl-CoA biosynthesis from acetyl-CoA|activation of butyryl-CoA biosynthetic process from acetyl-CoA|positive regulation of butyryl-CoA biosynthesis from acetyl-CoA|up-regulation of butyryl-CoA biosynthetic process from acetyl-CoA						tt	2012-05-02T03:51:58Z						biological_process											owl:Class	
GO:0008617	biolink:NamedThing	guanosine metabolic process	The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.	got7fsn_ti	guanosine metabolism													biological_process											owl:Class	
GO:1903876	biolink:NamedThing	11-deoxycortisol binding	Binding to 11-deoxycortisol.	got7fsn_ti							mr	2015-02-06T16:02:44Z						molecular_function											owl:Class	
GO:0040028	biolink:NamedThing	regulation of vulval development	Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.	got7fsn_ti														biological_process											owl:Class	
GO:0000053	biolink:NamedThing	argininosuccinate metabolic process	The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate.	got7fsn_ti	argininosuccinate metabolism													biological_process											owl:Class	
GO:0046398	biolink:NamedThing	UDP-glucuronate metabolic process	The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-glucuronate metabolism													biological_process											owl:Class	
GO:1902820	biolink:NamedThing	1-undecene metabolic process	The chemical reactions and pathways involving 1-undecene.	got7fsn_ti	1-undecene metabolism						tt	2014-03-31T02:50:48Z						biological_process											owl:Class	
GO:0030009	biolink:NamedThing	obsolete complement factor H activity	OBSOLETE. A cofactor for the serine protease complement factor I.	got7fsn_ti	complement factor H activity				This term was made obsolete because it represents a gene product.	GO:0006956				True				molecular_function											owl:Class	
GO:1901245	biolink:NamedThing	positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization	The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling.	got7fsn_ti	positive regulation of TLR9 signaling pathway by B cell receptor internalization|positive regulation of toll-like receptor 9 signalling pathway by BCR endocytosis|positive regulation of TLR9 signaling pathway by BCR receptor internalization|positive regulation of TLR9 signaling pathway by BCR endocytosis|positive regulation of toll-like receptor 9 signalling pathway by B cell receptor internalization|BCR-induced TLR9 recruitment|positive regulation of toll-like receptor 9 signaling pathway by BCR receptor internalization|positive regulation of toll-like receptor 9 signalling pathway by BCR receptor internalization|positive regulation of toll-like receptor 9 signaling pathway by BCR endocytosis						bf	2012-08-08T08:12:44Z						biological_process											owl:Class	
GO:0032185	biolink:NamedThing	septin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins.	got7fsn_ti	septin cytoskeleton organisation|septin cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:1905282	biolink:NamedThing	regulation of epidermal growth factor receptor signaling pathway involved in heart process	Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.	got7fsn_ti	regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|regulation of EGF receptor signalling pathway involved in heart process|regulation of ERBB1 signaling pathway involved in heart process|regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|regulation of EGF receptor signalling pathway involved in cardiac process|regulation of epidermal growth factor receptor signalling pathway involved in heart process|regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in heart process|regulation of ERBB1 signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in heart process						bc	2016-06-20T14:40:41Z						biological_process											owl:Class	
GO:0046128	biolink:NamedThing	purine ribonucleoside metabolic process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	purine ribonucleoside metabolism													biological_process											owl:Class	
GO:0015933	biolink:NamedThing	obsolete flavin-containing electron transporter	OBSOLETE. An oxidoreductase which contains either flavin-adenine dinucleotide or flavin mononucleotide as a prosthetic group, utilizes either NADH or NADPH and transfers electrons to other electron transfer proteins.	got7fsn_ti	flavin-containing electron transporter			GO:0009055	This term was made obsolete because it does not describe a molecular function.					True				molecular_function											owl:Class	
GO:0150173	biolink:NamedThing	positive regulation of phosphatidylcholine metabolic process	Any process that activates or increases the frequency, rate or extent of phosphatidylcholine metabolic process.	got7fsn_ti							bc	2020-01-21T14:03:28Z						biological_process											owl:Class	
GO:1900493	biolink:NamedThing	positive regulation of [4Fe-4S] cluster assembly	Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly.	got7fsn_ti	positive regulation of 4Fe-4S cluster assembly|up regulation of 4Fe-4S cluster assembly|positive regulation of [4Fe-4S] cluster biosynthetic process|upregulation of 4Fe-4S cluster assembly|up-regulation of [4Fe-4S] cluster biosynthetic process|upregulation of [4Fe-4S] cluster assembly|activation of [4Fe-4S] cluster biosynthetic process|up regulation of [4Fe-4S] cluster assembly|upregulation of [4Fe-4S] cluster biosynthetic process|up regulation of [4Fe-4S] cluster biosynthetic process|up-regulation of 4Fe-4S cluster assembly|activation of 4Fe-4S cluster assembly|activation of [4Fe-4S] cluster assembly|up-regulation of [4Fe-4S] cluster assembly						tt	2012-05-02T03:49:10Z						biological_process											owl:Class	
GO:0006329	biolink:NamedThing	obsolete satellite DNA binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	satellite DNA binding			GO:0003696	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:1904394	biolink:NamedThing	negative regulation of skeletal muscle acetylcholine-gated channel clustering	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.	got7fsn_ti	downregulation of skeletal muscle nicotinic acetylcholine receptor clustering|down regulation of skeletal muscle nicotinic acetylcholine receptor clustering|down regulation of skeletal muscle AChR clustering|down-regulation of skeletal muscle AChR clustering|down-regulation of skeletal muscle nicotinic acetylcholine receptor clustering|inhibition of skeletal muscle nicotinic acetylcholine receptor clustering|inhibition of skeletal muscle acetylcholine-gated channel clustering|down regulation of skeletal muscle acetylcholine-gated channel clustering|inhibition of skeletal muscle AChR clustering|negative regulation of skeletal muscle nicotinic acetylcholine receptor clustering|downregulation of skeletal muscle AChR clustering|down-regulation of skeletal muscle acetylcholine-gated channel clustering|negative regulation of skeletal muscle AChR clustering|downregulation of skeletal muscle acetylcholine-gated channel clustering						sl	2015-06-23T19:23:31Z						biological_process											owl:Class	
GO:0075251	biolink:NamedThing	uredospore formation	The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus.	got7fsn_ti	urediniospore formation|ureidospore formation													biological_process											owl:Class	
GO:1905566	biolink:NamedThing	obsolete negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport.	got7fsn_ti	down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of LDL|negative regulation of receptor-mediated endocytosis of LDL|downregulation of receptor-mediated endocytosis of LDL|down regulation of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|inhibition of receptor-mediated endocytosis of LDL				This term was obsoleted at the TermGenie Gatekeeper stage.		nc	2016-10-18T10:58:46Z		True				biological_process											owl:Class	
GO:0045743	biolink:NamedThing	positive regulation of fibroblast growth factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.	got7fsn_ti	activation of fibroblast growth factor receptor signaling pathway|up regulation of fibroblast growth factor receptor signaling pathway|positive regulation of FGFR signaling pathway|up-regulation of fibroblast growth factor receptor signaling pathway|upregulation of fibroblast growth factor receptor signaling pathway|stimulation of fibroblast growth factor receptor signaling pathway|positive regulation of FGF receptor signalling pathway|positive regulation of FGF receptor signaling pathway													biological_process											owl:Class	
GO:1903795	biolink:NamedThing	regulation of inorganic anion transmembrane transport	Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport.	got7fsn_ti	regulation of transmembrane inorganic anion transport|regulation of inorganic anion membrane transport						sl	2015-01-14T21:44:49Z						biological_process											owl:Class	
GO:0033685	biolink:NamedThing	negative regulation of luteinizing hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.	got7fsn_ti	down-regulation of luteinizing hormone secretion|down regulation of luteinizing hormone secretion|inhibition of luteinizing hormone secretion|downregulation of luteinizing hormone secretion													biological_process											owl:Class	
GO:1990540	biolink:NamedThing	mitochondrial manganese ion transmembrane transport	The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T11:03:09Z						biological_process											owl:Class	
GO:1901774	biolink:NamedThing	lincomycin biosynthetic process	The chemical reactions and pathways resulting in the formation of lincomycin.	got7fsn_ti	lincomycin anabolism|lincomycin synthesis|lincomycin formation|lincomycin biosynthesis						yaf	2013-01-15T11:54:01Z						biological_process											owl:Class	
GO:1905238	biolink:NamedThing	cellular response to cyclosporin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.	got7fsn_ti	cellular response to cyclophilin						sl	2016-06-07T21:32:14Z						biological_process											owl:Class	
GO:1900089	biolink:NamedThing	negative regulation of inositol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process.	got7fsn_ti	downregulation of myo-inositol biosynthesis|negative regulation of inositol synthesis|negative regulation of myo-inositol biosynthetic process|inhibition of myo-inositol biosynthetic process|down-regulation of vitamin Bh biosynthetic process|down-regulation of inositol synthesis|downregulation of vitamin Bh biosynthetic process|negative regulation of vitamin Bh biosynthetic process|down-regulation of myo-inositol biosynthesis|downregulation of inositol formation|down-regulation of vitamin Bh biosynthesis|down regulation of myo-inositol biosynthesis|inhibition of vitamin Bh biosynthesis|negative regulation of inositol anabolism|downregulation of inositol anabolism|downregulation of vitamin Bh biosynthesis|down regulation of inositol anabolism|inhibition of myo-inositol biosynthesis|inhibition of inositol biosynthetic process|inhibition of inositol formation|negative regulation of inositol biosynthesis|downregulation of inositol synthesis|down regulation of inositol formation|down-regulation of inositol formation|down-regulation of myo-inositol biosynthetic process|inhibition of vitamin Bh biosynthetic process|downregulation of inositol biosynthesis|downregulation of inositol biosynthetic process|down regulation of inositol biosynthesis|down regulation of vitamin Bh biosynthesis|down regulation of myo-inositol biosynthetic process|down-regulation of inositol biosynthesis|down regulation of vitamin Bh biosynthetic process|inhibition of inositol synthesis|inhibition of inositol anabolism|negative regulation of myo-inositol biosynthesis|down regulation of inositol biosynthetic process|negative regulation of vitamin Bh biosynthesis|inhibition of inositol biosynthesis|down-regulation of inositol biosynthetic process|down regulation of inositol synthesis|downregulation of myo-inositol biosynthetic process|down-regulation of inositol anabolism|negative regulation of inositol formation						dhl	2012-02-08T06:27:28Z						biological_process											owl:Class	
GO:0045542	biolink:NamedThing	positive regulation of cholesterol biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.	got7fsn_ti	up regulation of cholesterol biosynthetic process|positive regulation of cholesterol anabolism|positive regulation of cholesterol formation|activation of cholesterol biosynthetic process|up-regulation of cholesterol biosynthetic process|positive regulation of cholesterol biosynthesis|positive regulation of cholesterol synthesis|stimulation of cholesterol biosynthetic process|upregulation of cholesterol biosynthetic process													biological_process											owl:Class	
GO:0045110	biolink:NamedThing	intermediate filament bundle assembly	The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.	got7fsn_ti	tonofilament assembly													biological_process											owl:Class	
GO:1904227	biolink:NamedThing	negative regulation of glycogen synthase activity, transferring glucose-1-phosphate	Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.	got7fsn_ti	down regulation of glycogen synthase activity, transferring glucose-1-phosphate|down-regulation of glycogen synthase activity, transferring glucose-1-phosphate|inhibition of glycogen synthase activity, transferring glucose-1-phosphate|downregulation of glycogen synthase activity, transferring glucose-1-phosphate						rl	2015-05-15T09:23:14Z						biological_process											owl:Class	
GO:1905433	biolink:NamedThing	negative regulation of retrograde trans-synaptic signaling by neuropeptide	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.	got7fsn_ti	down-regulation of retrograde trans-synaptic signaling by neuropeptide|inhibition of retrograde trans-synaptic signaling by neuropeptide|downregulation of retrograde trans-synaptic signaling by neuropeptide|down regulation of retrograde trans-synaptic signaling by neuropeptide|inhibition of neuropeptide-mediated retrograde trans-synaptic signaling|negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling						bf	2016-09-14T10:56:55Z						biological_process											owl:Class	
GO:1901167	biolink:NamedThing	3-chlorocatechol metabolic process	The chemical reactions and pathways involving 3-chlorocatechol.	got7fsn_ti	3-chlorocatechol metabolism						yaf	2012-07-19T09:33:16Z						biological_process											owl:Class	
GO:1904243	biolink:NamedThing	negative regulation of pancreatic trypsinogen secretion	Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion.	got7fsn_ti	down regulation of pancreatic trypsinogen release|negative regulation of pancreatic trypsinogen release|down regulation of pancreatic trypsinogen secretion|downregulation of pancreatic trypsinogen secretion|down-regulation of pancreatic trypsinogen secretion|inhibition of pancreatic trypsinogen release|downregulation of pancreatic trypsinogen release|inhibition of pancreatic trypsinogen secretion|down-regulation of pancreatic trypsinogen release						sl	2015-05-18T19:49:27Z						biological_process											owl:Class	
GO:0002728	biolink:NamedThing	negative regulation of natural killer cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.	got7fsn_ti	down-regulation of natural killer cell cytokine production|downregulation of natural killer cell cytokine production|negative regulation of NK cell cytokine production|down regulation of natural killer cell cytokine production|inhibition of natural killer cell cytokine production													biological_process											owl:Class	
GO:2001054	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process.	got7fsn_ti	negative regulation of mesenchymal cell apoptosis						yaf	2011-09-08T02:50:05Z						biological_process											owl:Class	
CHEBI:17972	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016659	biolink:NamedThing	obsolete oxidoreductase activity, acting on NADH or NADPH, other acceptor	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, a heme protein, NAD, NADP, a nitrogenous group, a quinone or similar compound or oxygen.	got7fsn_ti	oxidoreductase activity, acting on NADH or NADPH, other acceptor				This term was made obsolete because it was an unnecessary grouping term.	GO:0016651				True				molecular_function											owl:Class	
GO:1903020	biolink:NamedThing	positive regulation of glycoprotein metabolic process	Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.	got7fsn_ti	up-regulation of glycoprotein metabolic process|upregulation of glycoprotein metabolic process|activation of glycoprotein metabolic process|activation of glycoprotein metabolism|up regulation of glycoprotein metabolism|positive regulation of glycoprotein metabolism|upregulation of glycoprotein metabolism|up regulation of glycoprotein metabolic process|up-regulation of glycoprotein metabolism				human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein		rl	2014-05-14T18:44:31Z						biological_process											owl:Class	
OIO:hasOBOFormatVersion	biolink:NamedThing	has_obo_format_version		got7fsn_ti																									owl:AnnotationProperty	
GO:1900724	biolink:NamedThing	positive regulation of protein adenylylation	Any process that activates or increases the frequency, rate or extent of protein adenylylation.	got7fsn_ti	up regulation of protein adenylylation|positive regulation of protein adenylation|activation of protein adenylylation|activation of protein AMPylation|up-regulation of protein amino acid adenylylation|upregulation of protein amino acid adenylylation|positive regulation of protein AMPylation|upregulation of protein AMPylation|up regulation of protein amino acid adenylylation|up-regulation of protein adenylation|activation of protein amino acid adenylylation|positive regulation of protein amino acid adenylylation|up regulation of protein AMPylation|up-regulation of protein adenylylation|up regulation of protein adenylation|upregulation of protein adenylylation|upregulation of protein adenylation|activation of protein adenylation|up-regulation of protein AMPylation						jl	2012-05-24T03:16:13Z						biological_process											owl:Class	
GO:0006229	biolink:NamedThing	dUTP biosynthetic process	The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate.	got7fsn_ti	dUTP formation|dUTP biosynthesis|dUTP synthesis|dUTP anabolism													biological_process											owl:Class	
GO:0006152	biolink:NamedThing	purine nucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	got7fsn_ti	purine nucleoside catabolism|purine nucleoside degradation|purine nucleoside breakdown													biological_process											owl:Class	
GO:1901986	biolink:NamedThing	response to ketamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus.	got7fsn_ti							dph	2013-03-15T19:16:35Z						biological_process											owl:Class	
GO:0051924	biolink:NamedThing	regulation of calcium ion transport	Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of calcium transport													biological_process											owl:Class	
GO:0010650	biolink:NamedThing	positive regulation of cell communication by electrical coupling	Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti														biological_process											owl:Class	
GO:0001027	biolink:NamedThing	obsolete RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	got7fsn_ti	RNA polymerase III type 1 promoter polymerase recruiting transcription factor activity				The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter.		krc	2010-08-23T12:50:20Z		True				molecular_function											owl:Class	
GO:1904873	biolink:NamedThing	negative regulation of telomerase RNA localization to Cajal body	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body.	got7fsn_ti	down-regulation of telomerase RNA localization to Cajal body|down regulation of telomerase RNA localization to Cajal body|downregulation of telomerase RNA localization to Cajal body|inhibition of telomerase RNA localization to Cajal body						nc	2015-12-18T11:28:27Z						biological_process											owl:Class	
GO:1902193	biolink:NamedThing	2-methylbut-2-enoyl-CoA(4-) catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-).	got7fsn_ti	2-methylbut-2-enoyl-CoA(4-) catabolism|2-methylbut-2-enoyl-CoA(4-) degradation|2-methylbut-2-enoyl-CoA(4-) breakdown						ms	2013-06-06T09:40:41Z						biological_process											owl:Class	
GO:1900044	biolink:NamedThing	regulation of protein K63-linked ubiquitination	Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination.	got7fsn_ti	regulation of protein K63-linked polyubiquitination						bf	2012-01-19T11:44:37Z						biological_process											owl:Class	
GO:1905557	biolink:NamedThing	regulation of mitotic nuclear envelope disassembly	Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.	got7fsn_ti	regulation of mitotic nuclear envelope breakdown|regulation of mitotic nuclear envelope degradation|regulation of mitotic nuclear envelope catabolism						hbye	2016-10-14T13:14:57Z						biological_process											owl:Class	
GO:0034760	biolink:NamedThing	negative regulation of iron ion transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	negative regulation of transmembrane iron ion transport|down regulation of transmembrane iron ion transport|negative regulation of iron ion membrane transport|inhibition of transmembrane iron ion transport|down-regulation of transmembrane iron ion transport|negative regulation of transmembrane iron transport|downregulation of transmembrane iron ion transport													biological_process											owl:Class	
GO:1903328	biolink:NamedThing	positive regulation of tRNA metabolic process	Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.	got7fsn_ti	upregulation of tRNA metabolism|up regulation of tRNA metabolism|up-regulation of tRNA metabolic process|upregulation of tRNA metabolic process|positive regulation of tRNA metabolism|activation of tRNA metabolic process|up regulation of tRNA metabolic process|activation of tRNA metabolism|up-regulation of tRNA metabolism						vw	2014-08-18T13:09:06Z						biological_process											owl:Class	
GO:0033252	biolink:NamedThing	regulation of beta-lactamase activity	Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid.	got7fsn_ti														biological_process											owl:Class	
GO:1903590	biolink:NamedThing	regulation of lysozyme activity	Any process that modulates the frequency, rate or extent of lysozyme activity.	got7fsn_ti	regulation of mucopeptide glucohydrolase activity|regulation of globulin G1|regulation of N,O-diacetylmuramidase activity|regulation of peptidoglycan N-acetylmuramoylhydrolase activity|regulation of L-7001|regulation of mucopeptide N-acetylmuramoylhydrolase activity|regulation of globulin G|regulation of muramidase activity|regulation of PR1-lysozyme|regulation of 1,4-N-acetylmuramidase activity|regulation of lysozyme g						mr	2014-11-05T21:41:22Z						biological_process											owl:Class	
GO:1903281	biolink:NamedThing	positive regulation of calcium:sodium antiporter activity	Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity.	got7fsn_ti	up regulation of sodium/calcium exchanger|positive regulation of sodium/calcium exchanger|positive regulation of mitochondrial sodium/calcium ion exchange|upregulation of sodium/calcium exchanger|up-regulation of sodium:calcium exchange|up-regulation of sodium/calcium exchanger|upregulation of calcium:sodium antiporter activity|activation of sodium:calcium exchange|positive regulation of sodium:calcium exchange|up-regulation of mitochondrial sodium/calcium ion exchange|activation of calcium:sodium antiporter activity|upregulation of sodium:calcium exchange|up regulation of mitochondrial sodium/calcium ion exchange|up regulation of sodium:calcium exchange|up regulation of calcium:sodium antiporter activity|upregulation of mitochondrial sodium/calcium ion exchange|up-regulation of calcium:sodium antiporter activity|activation of mitochondrial sodium/calcium ion exchange|activation of sodium/calcium exchanger						rl	2014-08-11T12:53:47Z						biological_process											owl:Class	
GO:0015899	biolink:NamedThing	aminotriazole transport	The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.	got7fsn_ti														biological_process											owl:Class	
GO:1900978	biolink:NamedThing	negative regulation of tatiopterin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process.	got7fsn_ti	inhibition of tatiopterin metabolism|down regulation of tatiopterin metabolism|downregulation of tatiopterin metabolism|down-regulation of tatiopterin metabolism|negative regulation of tatiopterin metabolism|inhibition of tatiopterin metabolic process|downregulation of tatiopterin metabolic process|down regulation of tatiopterin metabolic process|down-regulation of tatiopterin metabolic process						tt	2012-06-14T04:03:29Z						biological_process											owl:Class	
GO:0009450	biolink:NamedThing	gamma-aminobutyric acid catabolic process	The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.	got7fsn_ti	4-aminobutyrate catabolism|4-aminobutanoate catabolic process|gamma-aminobutyric acid catabolism|4-aminobutyrate catabolic process|GABA catabolism|gamma-aminobutyric acid degradation|gamma-aminobutyric acid breakdown|GABA catabolic process|4-aminobutanoate catabolism				See also the biological process term 'neurotransmitter catabolic process ; GO:0042135'.							MetaCyc:4AMINOBUTMETAB-PWY		biological_process											owl:Class	
GO:0062212	biolink:NamedThing	regulation of mitotic DNA replication initiation from early origin	Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication.	got7fsn_ti	regulation of early replication origin firing						dph	2020-02-21T19:21:44Z						biological_process											owl:Class	
CHEBI:30848	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006800	biolink:NamedThing	obsolete oxygen and reactive oxygen species metabolic process	OBSOLETE. The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).	got7fsn_ti	oxygen and AOS metabolism|oxygen and active oxygen species metabolism|oxygen and ROS metabolic process|oxygen and reactive oxygen species metabolic process|oxygen and reactive oxygen intermediate metabolism|oxygen and reactive oxygen species metabolism|oxygen and reactive oxidative species metabolism|oxygen and ROS metabolism|oxygen and ROI metabolism				This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together.	GO:0072592|GO:0072593				True				biological_process											owl:Class	
GO:0023006	biolink:NamedThing	obsolete signal initiation by amino acid	OBSOLETE. The process in which an amino acid signal causes activation of a receptor.	got7fsn_ti	signal initiation by amino acid				This term was made obsolete because the meaning of the term is ambiguous.	GO:0008066|GO:0071230|GO:0007215		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0032959	biolink:NamedThing	inositol trisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.	got7fsn_ti	inositol trisphosphate biosynthesis|inositol trisphosphate formation|IP3 biosynthetic process|myo-inositol trisphosphate biosynthetic process|inositol trisphosphate synthesis|inositol trisphosphate anabolism|IP3 biosynthesis													biological_process											owl:Class	
GO:2001216	biolink:NamedThing	negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	Any process that stops, prevents or reduces the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.	got7fsn_ti	negative regulation of HMG-CoA reductase activity|negative regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity						bf	2011-11-16T11:34:17Z						biological_process											owl:Class	
GO:0106183	biolink:NamedThing	obsolete translocase activity acting on carbohydrates and their derivatives.	OBSOLETE. Catalysis of the translocation of carbohydrates and their derivatives.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:54:25Z		True		EC:7.5.-.-		molecular_function											owl:Class	
GO:0046647	biolink:NamedThing	negative regulation of gamma-delta T cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation.	got7fsn_ti	down-regulation of gamma-delta T cell proliferation|negative regulation of gamma-delta T-lymphocyte proliferation|negative regulation of gamma-delta T lymphocyte proliferation|negative regulation of gamma-delta T-cell proliferation|down regulation of gamma-delta T cell proliferation|downregulation of gamma-delta T cell proliferation|inhibition of gamma-delta T cell proliferation													biological_process											owl:Class	
GO:0070896	biolink:NamedThing	positive regulation of transposon integration	Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.	got7fsn_ti	up regulation of transposon integration|upregulation of transposon integration|up-regulation of transposon integration|activation of transposon integration|stimulation of transposon integration						mah	2009-09-01T04:25:06Z						biological_process											owl:Class	
GO:0060998	biolink:NamedThing	regulation of dendritic spine development	Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.	got7fsn_ti							dph	2010-01-20T09:17:06Z						biological_process											owl:Class	
GO:1902526	biolink:NamedThing	negative regulation of protein monoubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination.	got7fsn_ti	down-regulation of protein monoubiquitylation|downregulation of protein monoubiquitinylation|inhibition of protein monoubiquitination|downregulation of protein monoubiquitylation|negative regulation of protein monoubiquitinylation|down regulation of protein monoubiquitination|down-regulation of protein monoubiquitinylation|inhibition of protein monoubiquitinylation|inhibition of protein monoubiquitylation|down regulation of protein monoubiquitinylation|down-regulation of protein monoubiquitination|down regulation of protein monoubiquitylation|downregulation of protein monoubiquitination|negative regulation of protein monoubiquitylation						ppm	2013-12-02T09:59:05Z						biological_process											owl:Class	
GO:1902955	biolink:NamedThing	positive regulation of early endosome to recycling endosome transport	Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport.	got7fsn_ti	up-regulation of early endosome to recycling endosome transport|activation of early endosome to recycling endosome transport|up regulation of early endosome to recycling endosome transport|upregulation of early endosome to recycling endosome transport						sjp	2014-05-02T09:06:29Z						biological_process											owl:Class	
GO:0019502	biolink:NamedThing	stachydrine metabolic process	The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants.	got7fsn_ti	stachydrine metabolism													biological_process											owl:Class	
GO:1900202	biolink:NamedThing	obsolete negative regulation of spread of virus in host, cell to cell	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of spread of virus in host, cell to cell.	got7fsn_ti	negative regulation of cell to cell spread of virus within host|negative regulation of spread of virus in host, cell to cell|downregulation of cell to cell spread of virus within host|downregulation of spread of virus within host, cell to cell|down regulation of viral spread within host, cell to cell|negative regulation of spread of virus within host, cell to cell|downregulation of viral spread within host, cell to cell|inhibition of spread of virus in host, cell to cell|down-regulation of spread of virus within host, cell to cell|downregulation of spread of virus in host, cell to cell|inhibition of cell to cell spread of virus within host|inhibition of spread of virus within host, cell to cell|inhibition of viral spread within host, cell to cell|down regulation of cell to cell spread of virus within host|down-regulation of spread of virus in host, cell to cell|down-regulation of cell to cell spread of virus within host|negative regulation of viral spread within host, cell to cell|down regulation of spread of virus within host, cell to cell|down regulation of spread of virus in host, cell to cell|down-regulation of viral spread within host, cell to cell				This term was obsoleted at the TermGenie Gatekeeper stage.		pm	2012-03-21T01:15:51Z		True				biological_process											owl:Class	
GO:0031015	biolink:NamedThing	obsolete karyopherin docking complex	OBSOLETE. A subcomplex of the nuclear pore complex that interacts with karyopherin-cargo complexes; a well-characterized example in Saccharomyces contains Asm4p, Nup53p, and Nup170p.	got7fsn_ti	Asm4p-containing complex|karyopherin docking complex|nuclear pore subcomplex					GO:0017056|GO:0044613				True				cellular_component											owl:Class	
GO:0090241	biolink:NamedThing	negative regulation of histone H4 acetylation	Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.	got7fsn_ti							tb	2010-01-20T03:48:09Z						biological_process											owl:Class	
GO:0150151	biolink:NamedThing	regulation of interleukin-17A production	Any process that modulates the frequency, rate or extent of interleukin-17A production.	got7fsn_ti	regulation of interleukin-17A biosynthetic process						bc	2019-12-11T07:44:52Z						biological_process											owl:Class	
GO:0071865	biolink:NamedThing	regulation of apoptotic process in bone marrow cell	Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow.	got7fsn_ti	regulation of apoptosis in bone marrow|regulation of apoptotic process in bone marrow						mah	2010-09-13T02:16:43Z						biological_process											owl:Class	
GO:0046179	biolink:NamedThing	keto-D-gluconate biosynthetic process	The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.	got7fsn_ti	keto-D-gluconate synthesis|keto-D-gluconate formation|keto-D-gluconate anabolism|keto-D-gluconate biosynthesis													biological_process											owl:Class	
GO:0045978	biolink:NamedThing	negative regulation of nucleoside metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.	got7fsn_ti	negative regulation of nucleoside metabolism|down-regulation of nucleoside metabolic process|down regulation of nucleoside metabolic process|inhibition of nucleoside metabolic process|downregulation of nucleoside metabolic process													biological_process											owl:Class	
GO:1901152	biolink:NamedThing	vistamycin biosynthetic process	The chemical reactions and pathways resulting in the formation of vistamycin.	got7fsn_ti	vistamycin anabolism|ribostamycin formation|ribostamycin anabolism|ribostamycin biosynthetic process|vistamycin formation|vistamycin biosynthesis|ribostamycin synthesis|ribostamycin biosynthesis|vistamycin synthesis						yaf	2012-07-17T04:27:15Z						biological_process											owl:Class	
GO:0042617	biolink:NamedThing	paclitaxel biosynthetic process	The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.	got7fsn_ti	paclitaxel synthesis|paclitaxel anabolism|taxol biosynthetic process|paclitaxel formation|taxol biosynthesis|paclitaxel biosynthesis													biological_process											owl:Class	
GO:0001912	biolink:NamedThing	positive regulation of leukocyte mediated cytotoxicity	Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity.	got7fsn_ti	activation of leukocyte mediated cytotoxicity|upregulation of leukocyte mediated cytotoxicity|positive regulation of leucocyte mediated cytotoxicity|up regulation of leukocyte mediated cytotoxicity|stimulation of leukocyte mediated cytotoxicity|positive regulation of immune cell mediated cytotoxicity|up-regulation of leukocyte mediated cytotoxicity													biological_process											owl:Class	
GO:1904191	biolink:NamedThing	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division	Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division.	got7fsn_ti	stimulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|positive regulation of CDK activity involved in meiotic nuclear division|positive regulation of cyclin-dependent protein kinase activity involved in meiosis|activation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|upregulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|up-regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|up regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division						al	2015-05-06T14:48:52Z						biological_process											owl:Class	
GO:1904670	biolink:NamedThing	actin filament polymerization involved in mitotic actomyosin contractile ring assembly	Any actin filament polymerization that is involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti							vw	2015-09-09T20:05:56Z						biological_process											owl:Class	
GO:0009869	biolink:NamedThing	obsolete incompatible pollen-pistil interaction	OBSOLETE. An interaction between a pollen grain and pistil that results in inhibition of pollen germination/growth.	got7fsn_ti	incompatible pollen-pistil interaction				This term was made obsolete because it represents a phenotype.					True				biological_process											owl:Class	
GO:1902680	biolink:NamedThing	positive regulation of RNA biosynthetic process	Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.	got7fsn_ti	upregulation of RNA biosynthetic process|positive regulation of RNA biosynthesis|up regulation of RNA anabolism|activation of RNA synthesis|up-regulation of RNA biosynthesis|activation of RNA biosynthesis|up-regulation of RNA biosynthetic process|positive regulation of RNA anabolism|up regulation of RNA biosynthesis|upregulation of RNA synthesis|positive regulation of RNA synthesis|activation of RNA biosynthetic process|upregulation of RNA anabolism|upregulation of RNA biosynthesis|positive regulation of RNA formation|up regulation of RNA synthesis|up-regulation of RNA formation|up-regulation of RNA synthesis|up-regulation of RNA anabolism|upregulation of RNA formation|activation of RNA formation|up regulation of RNA formation|up regulation of RNA biosynthetic process|activation of RNA anabolism						jl	2014-02-05T16:32:10Z						biological_process											owl:Class	
GO:1903098	biolink:NamedThing	negative regulation of CENP-A containing nucleosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.	got7fsn_ti	negative regulation of CenH3-containing nucleosome assembly at centromere|downregulation of centromere specific nucleosome exchange|inhibition of DNA replication-independent nucleosome assembly at centromere|negative regulation of CENP-A deposition|negative regulation of centromeric DNA replication-independent nucleosome assembly|inhibition of centromeric DNA replication-independent nucleosome assembly|downregulation of CENP-A deposition|down-regulation of centromere-specific nucleosome assembly|negative regulation of CENP-A loading|down-regulation of centromeric DNA replication-independent nucleosome assembly|down-regulation of CENP-A containing nucleosome assembly at centromere|down regulation of CENP-A deposition|down regulation of CenH3-containing nucleosome assembly at centromere|downregulation of CENP-A loading|downregulation of centromere-specific nucleosome assembly|down-regulation of CENP-A loading|down regulation of DNA replication-independent nucleosome assembly at centromere|downregulation of CenH3-containing nucleosome assembly at centromere|negative regulation of centromere-specific nucleosome assembly|down regulation of centromere specific nucleosome exchange|negative regulation of centromere-specific histone exchange|inhibition of CENP-A containing nucleosome assembly at centromere|down regulation of centromere-specific histone exchange|inhibition of centromere-specific nucleosome assembly|down regulation of centromere-specific nucleosome assembly|downregulation of DNA replication-independent nucleosome assembly at centromere|down-regulation of centromere-specific histone exchange|downregulation of CENP-A containing nucleosome assembly at centromere|downregulation of centromere-specific histone exchange|inhibition of centromere specific nucleosome exchange|inhibition of CENP-A deposition|down-regulation of CENP-A deposition|inhibition of CenH3-containing nucleosome assembly at centromere|downregulation of centromeric DNA replication-independent nucleosome assembly|down-regulation of CenH3-containing nucleosome assembly at centromere|inhibition of CENP-A loading|down regulation of CENP-A loading|negative regulation of DNA replication-independent nucleosome assembly at centromere|down regulation of CENP-A containing nucleosome assembly at centromere|down regulation of centromeric DNA replication-independent nucleosome assembly|inhibition of centromere-specific histone exchange|down-regulation of centromere specific nucleosome exchange|down-regulation of DNA replication-independent nucleosome assembly at centromere|negative regulation of centromere specific nucleosome exchange						vw	2014-06-03T16:15:36Z						biological_process											owl:Class	
PR:000001475	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904491	biolink:NamedThing	protein localization to ciliary transition zone	A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.	got7fsn_ti	protein localisation to ciliary transition zone|protein localization in ciliary transition zone|protein localisation in ciliary transition zone						kmv	2015-07-17T20:43:21Z						biological_process											owl:Class	
GO:1905931	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.	got7fsn_ti	down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|downregulation of VSMC differentiation involved in phenotypic switching|down regulation of VSMC differentiation involved in phenotypic switching|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|inhibition of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of VSMC differentiation involved in phenotypic switching|down regulation of VSMC differentiation involved in phenotypic dimorphism|inhibition of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of VSMC differentiation involved in phenotypic dimorphism|down regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|down regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of VSMC differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of VSMC differentiation involved in phenotypic switching|negative regulation of VSMC differentiation involved in phenotypic switching|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of VSMC differentiation involved in phenotypic dimorphism|inhibition of VSMC differentiation involved in phenotypic dimorphism|negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism						rph	2017-02-09T09:21:08Z						biological_process											owl:Class	
GO:0005908	biolink:NamedThing	obsolete HA2 clathrin adaptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	HA2 clathrin adaptor|AP2				This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous.	GO:0030122				True				cellular_component											owl:Class	
GO:0003818	biolink:NamedThing	obsolete complement factor I activity	OBSOLETE. Catalysis of the inactivation of complement subcomponents C3b, iC3b and C4b by proteolytic cleavage.	got7fsn_ti	complement component C3b inactivator activity|C3b inactivator activity|C3b/C4b inactivator activity|C3bINA|conglutinogen-activating factor C|complement factor I activity|complement C4bi|factor I|complement C3b inactivator|complement C3b/C4b inactivator|complement C4b inactivator			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905409	biolink:NamedThing	positive regulation of creatine transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity.	got7fsn_ti	up-regulation of creatine transmembrane transporter activity|up regulation of creatine transmembrane transporter activity|upregulation of creatine transmembrane transporter activity|activation of creatine transmembrane transporter activity						bc	2016-08-25T15:09:04Z						biological_process											owl:Class	
GO:1905022	biolink:NamedThing	negative regulation of threonine-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of threonine-tRNA ligase activity.	got7fsn_ti	downregulation of TRS|down regulation of threonine-tRNA ligase activity|negative regulation of L-threonine:tRNAThr ligase (AMP-forming)|negative regulation of threonyl-tRNA synthetase activity|down-regulation of L-threonine:tRNAThr ligase (AMP-forming)|inhibition of TRS|inhibition of threonine-tRNA ligase activity|down regulation of threonine translase activity|downregulation of L-threonine:tRNAThr ligase (AMP-forming)|inhibition of threonyl-transfer ribonucleic acid synthetase activity|inhibition of threonyl ribonucleic synthetase activity|negative regulation of threonyl-transfer ribonucleic acid synthetase activity|down regulation of threonyl-transfer ribonucleic acid synthetase activity|down-regulation of threonyl ribonucleic synthetase activity|down-regulation of threonine-transfer ribonucleate synthetase activity|downregulation of threonine translase activity|inhibition of threonyl-transfer RNA synthetase activity|inhibition of threonyl-transfer ribonucleate synthetase activity|down-regulation of threonyl-transfer RNA synthetase activity|down regulation of threonine-transfer ribonucleate synthetase activity|down regulation of threonyl ribonucleic synthetase activity|downregulation of threonine-transfer ribonucleate synthetase activity|down-regulation of threonyl-transfer ribonucleic acid synthetase activity|negative regulation of threonyl-transfer ribonucleate synthetase activity|downregulation of threonyl-transfer ribonucleic acid synthetase activity|negative regulation of threonyl-transfer RNA synthetase activity|down regulation of threonyl-transfer RNA synthetase activity|negative regulation of TRS|downregulation of threonyl-tRNA synthetase activity|downregulation of threonyl-transfer RNA synthetase activity|inhibition of threonyl-tRNA synthetase activity|down regulation of threonyl-transfer ribonucleate synthetase activity|downregulation of threonyl-transfer ribonucleate synthetase activity|down-regulation of threonine translase activity|negative regulation of threonine translase activity|inhibition of L-threonine:tRNAThr ligase (AMP-forming)|down regulation of L-threonine:tRNAThr ligase (AMP-forming)|down-regulation of threonine-tRNA ligase activity|inhibition of threonine translase activity|negative regulation of threonyl ribonucleic synthetase activity|down-regulation of TRS|negative regulation of threonine-transfer ribonucleate synthetase activity|downregulation of threonine-tRNA ligase activity|down regulation of TRS|down-regulation of threonyl-tRNA synthetase activity|downregulation of threonyl ribonucleic synthetase activity|down-regulation of threonyl-transfer ribonucleate synthetase activity|inhibition of threonine-transfer ribonucleate synthetase activity|down regulation of threonyl-tRNA synthetase activity						sl	2016-03-03T19:12:32Z						biological_process											owl:Class	
GO:1903779	biolink:NamedThing	regulation of cardiac conduction	Any process that modulates the frequency, rate or extent of cardiac conduction.	got7fsn_ti							rph	2015-01-07T13:20:11Z						biological_process											owl:Class	
GO:1901885	biolink:NamedThing	2-hydroxybenzoyl-CoA metabolic process	The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA.	got7fsn_ti	2-hydroxybenzoyl-CoA metabolism						ms	2013-02-06T14:06:03Z						biological_process											owl:Class	
GO:1905501	biolink:NamedThing	obsolete heteroreceptor complex disassembly	OBSOLETE. The disaggregation of a heteroreceptor complex into its constituent components.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		pad	2016-09-27T10:50:04Z		True				biological_process											owl:Class	
CHEBI:60836	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070809	biolink:NamedThing	negative regulation of Hulle cell development	Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.	got7fsn_ti							mah	2009-07-08T04:53:11Z						biological_process											owl:Class	
GO:0044664	biolink:NamedThing	obsolete reversion of cell type to default state involved in phenotypic switching	OBSOLETE. The cellular process of the reversion of cells to their original cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.	got7fsn_ti					This term was made obsolete because it is ambiguous.		jl	2012-08-07T14:35:48Z		True				biological_process											owl:Class	
GO:0001739	biolink:NamedThing	sex chromatin	Chromatin that is part of a sex chromosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0006051	biolink:NamedThing	N-acetylmannosamine metabolic process	The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.	got7fsn_ti	N-acetylmannosamine metabolism													biological_process											owl:Class	
GO:0090053	biolink:NamedThing	positive regulation of pericentric heterochromatin assembly	Any process that increases the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.	got7fsn_ti	positive regulation of chromatin silencing at centromere	https://github.com/geneontology/go-ontology/issues/19112					tb	2009-08-07T10:49:40Z						biological_process											owl:Class	
GO:2000711	biolink:NamedThing	positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric	Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.	got7fsn_ti	positive regulation of maintenance of centromeric meiotic sister chromatin cohesion|positive regulation of maintenance of meiotic sister chromatin cohesion at centromere|positive regulation of maintenance of sister chromatin cohesion at centromere at meiosis I						mah	2011-06-01T12:41:18Z						biological_process											owl:Class	
GO:1905864	biolink:NamedThing	regulation of Atg1/ULK1 kinase complex assembly	Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.	got7fsn_ti	regulation of ULK1-ATG13-RB1CC1 complex formation|regulation of ATG1/ULK1 kinase complex formation|regulation of ULK1 signaling complex assembly|regulation of ATG1 kinase complex assembly|regulation of Atg1p signalling complex formation|regulation of ATG1-ATG13 complex assembly|regulation of ULK1 signaling complex formation|regulation of ULK1-ATG13-FIP200 complex assembly|regulation of ULK1-ATG13-FIP200 complex formation|regulation of Atg1p signalling complex assembly|regulation of ATG1/ULK1 signaling complex formation|regulation of ATG1-ATG13 complex formation|regulation of ULK1-ATG13-RB1CC1 complex assembly|regulation of ATG1/ULK1 signaling complex assembly|regulation of ATG1 kinase complex formation						pr	2017-01-26T13:23:26Z						biological_process											owl:Class	
GO:1905067	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in heart development	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.	got7fsn_ti	downregulation of canonical Wnt receptor signaling pathway involved in heart development|down-regulation of canonical Wnt signaling pathway involved in heart development|down regulation of canonical Wnt receptor signaling pathway involved in heart development|downregulation of canonical Wnt signaling pathway involved in heart development|inhibition of canonical Wnt receptor signalling pathway involved in heart development|down regulation of canonical Wnt signaling pathway involved in heart development|inhibition of canonical Wnt signaling pathway involved in heart development|down-regulation of canonical Wnt receptor signaling pathway involved in heart development|downregulation of canonical Wnt receptor signalling pathway involved in heart development|inhibition of canonical Wnt-activated signaling pathway involved in heart development|negative regulation of canonical Wnt-activated signaling pathway involved in heart development|down-regulation of canonical Wnt-activated signaling pathway involved in heart development|downregulation of canonical Wnt-activated signaling pathway involved in heart development|down regulation of canonical Wnt receptor signalling pathway involved in heart development|down regulation of canonical Wnt-activated signaling pathway involved in heart development|down-regulation of canonical Wnt receptor signalling pathway involved in heart development|inhibition of canonical Wnt receptor signaling pathway involved in heart development|negative regulation of canonical Wnt receptor signalling pathway involved in heart development|negative regulation of canonical Wnt receptor signaling pathway involved in heart development						bc	2016-03-21T12:47:06Z						biological_process											owl:Class	
GO:0008471	biolink:NamedThing	obsolete laccase activity	OBSOLETE. Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.	got7fsn_ti	urushiol oxidase activity|laccase activity|urishiol oxidase activity|p-diphenol oxidase activity|benzenediol:oxygen oxidoreductase activity			GO:0016682						True				molecular_function											owl:Class	
GO:1902284	biolink:NamedThing	neuron projection extension involved in neuron projection guidance	Any neuron projection extension that is involved in neuron projection guidance.	got7fsn_ti	neuronal cell projection extension involved in neurite guidance|neuron projection extension involved in neuron protrusion guidance|neuronal cell projection extension involved in neuron process guidance|neurite extension involved in neuron projection guidance|neuron projection extension involved in neuronal cell projection guidance|neuron projection extension involved in neurite guidance|neuron protrusion extension involved in neuron protrusion guidance|neuron process extension involved in neuronal cell projection guidance|neuron process extension involved in neurite guidance|neurite extension involved in neurite guidance|neurite extension involved in neuron process guidance|neuron process extension involved in neuron protrusion guidance|neurite extension involved in neuron protrusion guidance|neuronal cell projection extension involved in neuron projection guidance|neuron process extension involved in neuron process guidance|neuron protrusion extension involved in neurite guidance|neuron projection extension involved in neuron process guidance|neuron protrusion extension involved in neuron process guidance|neuron process extension involved in neuron projection guidance|neurite extension involved in neuronal cell projection guidance|neuronal cell projection extension involved in neuronal cell projection guidance|neuron protrusion extension involved in neuronal cell projection guidance|neuron protrusion extension involved in neuron projection guidance|neuronal cell projection extension involved in neuron protrusion guidance						pr	2013-07-08T15:55:17Z						biological_process											owl:Class	
GO:1904435	biolink:NamedThing	regulation of transferrin receptor binding	Any process that modulates the frequency, rate or extent of transferrin receptor binding.	got7fsn_ti							kom	2015-07-06T13:49:01Z						biological_process											owl:Class	
GO:0046319	biolink:NamedThing	positive regulation of glucosylceramide biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.	got7fsn_ti	upregulation of glucosylceramide biosynthetic process|activation of glucosylceramide biosynthetic process|stimulation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide synthesis|positive regulation of glucosylceramide formation|up regulation of glucosylceramide biosynthetic process|up-regulation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide biosynthesis|positive regulation of glucosylceramide anabolism													biological_process											owl:Class	
GO:2001261	biolink:NamedThing	negative regulation of semaphorin-plexin signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway.	got7fsn_ti	negative regulation of semaphorin-plexin signalling pathway						vk	2011-12-08T02:05:48Z						biological_process											owl:Class	
GO:0015263	biolink:NamedThing	obsolete amine/amide/polyamine channel activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	amine/amide/polyamine channel activity				This term was made obsolete because it represents three molecular functions.	GO:0005275|GO:0015203|GO:0042887				True				molecular_function											owl:Class	
GO:0015661	biolink:NamedThing	L-lysine efflux transmembrane transporter activity	Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	L-lysine, 2,6-diaminohexanoic acid efflux transmembrane transporter activity|L-lysine exporter activity													molecular_function											owl:Class	
GO:0010320	biolink:NamedThing	obsolete arginine/lysine endopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a reaction mechanism in which arginine or lysine residues act as nucleophiles.	got7fsn_ti	arginine/lysine endopeptidase activity				This term was made obsolete because it was defined incorrectly: there are no known peptidases using a catalytic mechanism involving arginine and lysine, and the Arabidopsis metacaspases that prompted addition of this term are in fact cysteine-type endopeptidases.	GO:0004197|GO:0004175				True				molecular_function											owl:Class	
GO:1905279	biolink:NamedThing	regulation of retrograde transport, endosome to Golgi	Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi.	got7fsn_ti	regulation of retrograde (endosome to Golgi) transport						bf	2016-06-20T12:25:29Z						biological_process											owl:Class	
GO:1902099	biolink:NamedThing	regulation of metaphase/anaphase transition of cell cycle	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle.	got7fsn_ti							jl	2013-05-02T12:45:15Z						biological_process											owl:Class	
GO:1905014	biolink:NamedThing	positive regulation of 'de novo' NAD biosynthetic process from tryptophan	Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.	got7fsn_ti	up-regulation of de novo NAD biosynthetic process from tryptophan|up regulation of 'de novo' NAD biosynthetic process from tryptophan|upregulation of de novo NAD biosynthetic process from tryptophan|positive regulation of de novo NAD biosynthetic process from tryptophan|up regulation of de novo NAD biosynthetic process from tryptophan|activation of 'de novo' NAD biosynthetic process from tryptophan|activation of de novo NAD biosynthetic process from tryptophan|up-regulation of 'de novo' NAD biosynthetic process from tryptophan|upregulation of 'de novo' NAD biosynthetic process from tryptophan						bf	2016-03-03T10:01:10Z						biological_process											owl:Class	
GO:0002379	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000115	biolink:NamedThing	obsolete regulation of transcription involved in S phase of mitotic cell cycle	OBSOLETE. A cell cycle process that regulates transcription such that the target genes are transcribed as part of the S phase of the mitotic cell cycle.	got7fsn_ti	S-phase-specific transcription in mitotic cell cycle|regulation of transcription involved in S phase of mitotic cell cycle|S-specific transcription in mitotic cell cycle|regulation of transcription involved in S-phase of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during S-phase of mitotic cell cycle				This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0000083|GO:0006357				True				biological_process											owl:Class	
GO:1901450	biolink:NamedThing	positive regulation of response to butan-1-ol	Any process that activates or increases the frequency, rate or extent of response to butan-1-ol.	got7fsn_ti	upregulation of response to butan-1-ol|up regulation of response to butan-1-ol|activation of response to butan-1-ol|up-regulation of response to butan-1-ol						tt	2012-10-02T14:17:17Z						biological_process											owl:Class	
GO:1902576	biolink:NamedThing	negative regulation of nuclear cell cycle DNA replication	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication.	got7fsn_ti	downregulation of nuclear cell cycle DNA replication|inhibition of DNA replication involved in S-phase|negative regulation of DNA replication involved in S phase|down regulation of nuclear cell cycle DNA replication|down-regulation of nuclear cell cycle DNA replication|negative regulation of DNA replication during S phase|downregulation of DNA replication involved in S-phase|down-regulation of DNA replication involved in S-phase|inhibition of DNA replication during S phase|negative regulation of DNA replication involved in S-phase|inhibition of DNA replication involved in S phase|down-regulation of DNA replication involved in S phase|inhibition of nuclear cell cycle DNA replication|down regulation of DNA replication involved in S-phase|downregulation of DNA replication during S phase|downregulation of DNA replication involved in S phase|down regulation of DNA replication involved in S phase|down regulation of DNA replication during S phase|down-regulation of DNA replication during S phase						mah	2013-12-17T14:03:02Z						biological_process											owl:Class	
GO:0033487	biolink:NamedThing	pelargonidin 3-O-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.	got7fsn_ti	pelargonidin 3-O-glucoside biosynthesis|pelargonidin 3-O-glucoside synthesis|pelargonidin 3-O-glucoside formation|pelargonidin 3-O-glucoside anabolism											MetaCyc:PWY-5125		biological_process											owl:Class	
GO:1905694	biolink:NamedThing	negative regulation of phosphatidic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process.	got7fsn_ti	down-regulation of phosphatidic acid anabolism|inhibition of phosphatidic acid biosynthetic process|negative regulation of phosphatidic acid formation|downregulation of phosphatidic acid biosynthetic process|downregulation of phosphatidic acid anabolism|inhibition of phosphatidic acid anabolism|down regulation of phosphatidic acid synthesis|negative regulation of phosphatidic acid biosynthesis|down-regulation of phosphatidic acid synthesis|inhibition of phosphatidic acid synthesis|down regulation of phosphatidic acid biosynthesis|inhibition of phosphatidic acid biosynthesis|down regulation of phosphatidic acid biosynthetic process|down-regulation of phosphatidic acid formation|down-regulation of phosphatidic acid biosynthesis|down regulation of phosphatidic acid anabolism|negative regulation of phosphatidic acid anabolism|negative regulation of phosphatidic acid synthesis|downregulation of phosphatidic acid synthesis|down-regulation of phosphatidic acid biosynthetic process|down regulation of phosphatidic acid formation|downregulation of phosphatidic acid formation|inhibition of phosphatidic acid formation|downregulation of phosphatidic acid biosynthesis						bc	2016-11-14T14:48:16Z						biological_process											owl:Class	
GO:0023054	biolink:NamedThing	obsolete signal initiation by stretch effect	OBSOLETE. The process in which a stretch signal causes activation of a receptor.	got7fsn_ti	signal initiation by stretch effect				This term was made obsolete because the meaning of the term is ambiguous.	GO:0007165|GO:0038023		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0031442	biolink:NamedThing	positive regulation of mRNA 3'-end processing	Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.	got7fsn_ti	up-regulation of mRNA 3'-end processing|up regulation of mRNA 3'-end processing|activation of mRNA 3'-end processing|stimulation of mRNA 3'-end processing|upregulation of mRNA 3'-end processing													biological_process											owl:Class	
GO:0070595	biolink:NamedThing	(1->3)-alpha-glucan metabolic process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.	got7fsn_ti	1,3-alpha-glucan metabolism|alpha-1,3 glucan metabolism|alpha-1,3 glucan metabolic process|1,3-alpha-glucan metabolic process						mah	2009-04-28T03:35:03Z						biological_process											owl:Class	
GO:0021835	biolink:NamedThing	chemoattraction involved in embryonic olfactory bulb interneuron precursor migration	The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb.	got7fsn_ti	positive chemotaxis involved in embryonic olfactory bulb interneuron precursor migration													biological_process											owl:Class	
GO:0046112	biolink:NamedThing	nucleobase biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.	got7fsn_ti	nucleobase anabolism|nucleobase formation|nucleobase biosynthesis|nucleobase synthesis													biological_process											owl:Class	
GO:1900230	biolink:NamedThing	positive regulation of single-species biofilm formation in or on host organism	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism.	got7fsn_ti	up regulation of single-species biofilm formation in or on host organism|activation of single-species biofilm formation in or on host organism|up-regulation of single-species biofilm formation in or on host organism|upregulation of single-species biofilm formation in or on host organism						di	2012-03-23T04:37:14Z						biological_process											owl:Class	
GO:1903373	biolink:NamedThing	positive regulation of endoplasmic reticulum tubular network organization	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization.	got7fsn_ti	up-regulation of ER tubular network organisation|activation of endoplasmic reticulum tubular network organisation|upregulation of ER tubular network organization|up regulation of ER tubular network organisation|activation of ER tubular network organisation|upregulation of endoplasmic reticulum tubular network organisation|up-regulation of ER tubular network organization|upregulation of ER tubular network organisation|activation of endoplasmic reticulum tubular network organization|positive regulation of endoplasmic reticulum tubular network organisation|up regulation of endoplasmic reticulum tubular network organization|up-regulation of endoplasmic reticulum tubular network organisation|positive regulation of ER tubular network organisation|activation of ER tubular network organization|up regulation of ER tubular network organization|positive regulation of ER tubular network organization|upregulation of endoplasmic reticulum tubular network organization|up regulation of endoplasmic reticulum tubular network organisation|up-regulation of endoplasmic reticulum tubular network organization						als	2014-08-22T11:01:31Z						biological_process											owl:Class	
GO:1902087	biolink:NamedThing	dimethylsulfoniopropionate catabolic process	The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin.	got7fsn_ti	S,S-dimethyl-beta-propiothetin catabolic process|S,S-dimethyl-beta-propiothetin catabolism|S,S-dimethyl-beta-propiothetin degradation|S,S-dimethyl-beta-propiothetin breakdown						tb	2013-04-26T17:29:13Z						biological_process											owl:Class	
GO:1904758	biolink:NamedThing	protein localization to new growing cell tip	A process in which a protein is transported to, or maintained in, a location within a new growing cell tip.	got7fsn_ti	protein localization to post-NETO new cell end|protein localization to post-new end take-off new cell tip|protein localization to new growing cell end|protein localisation to new growing cell tip|protein localisation in new growing cell tip|protein localization in new growing cell tip|protein localization to new cell tip after activation of bipolar cell growth|protein localization to post-NETO new cell tip						mah	2015-10-21T12:37:48Z						biological_process											owl:Class	
GO:0030285	biolink:NamedThing	integral component of synaptic vesicle membrane	The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to synaptic vesicle membrane													cellular_component											owl:Class	
GO:1900672	biolink:NamedThing	positive regulation of F-9775A biosynthetic process	Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process.	got7fsn_ti	up-regulation of F-9775A anabolism|upregulation of F-9775A biosynthetic process|up-regulation of F-9775A formation|positive regulation of F-9775A biosynthesis|up-regulation of F-9775A biosynthetic process|upregulation of F-9775A anabolism|up regulation of F-9775A formation|positive regulation of F-9775A formation|up-regulation of F-9775A synthesis|upregulation of F-9775A formation|activation of F-9775A anabolism|activation of F-9775A biosynthesis|up regulation of F-9775A anabolism|upregulation of F-9775A biosynthesis|upregulation of F-9775A synthesis|up regulation of F-9775A synthesis|activation of F-9775A biosynthetic process|positive regulation of F-9775A anabolism|up-regulation of F-9775A biosynthesis|up regulation of F-9775A biosynthetic process|activation of F-9775A synthesis|up regulation of F-9775A biosynthesis|activation of F-9775A formation|positive regulation of F-9775A synthesis						di	2012-05-22T04:24:37Z						biological_process											owl:Class	
GO:1901283	biolink:NamedThing	5,6,7,8-tetrahydromethanopterin metabolic process	The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin.	got7fsn_ti	5,6,7,8-tetrahydromethanopterin metabolism						yaf	2012-08-17T15:32:33Z						biological_process											owl:Class	
GO:0032008	biolink:NamedThing	positive regulation of TOR signaling	Any process that activates or increases the frequency, rate or extent of TOR signaling.	got7fsn_ti	stimulation of TOR signaling pathway|positive regulation of TOR signaling cascade|activation of TOR signaling pathway|up regulation of TOR signaling pathway|positive regulation of target of rapamycin signalling pathway|positive regulation of TOR signalling pathway|up-regulation of TOR signaling pathway|positive regulation of target of rapamycin signaling pathway|positive regulation of TOR signaling pathway|upregulation of TOR signaling pathway													biological_process											owl:Class	
GO:2000704	biolink:NamedThing	positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.	got7fsn_ti	positive regulation of FGF receptor signaling pathway of ureteric bud formation|positive regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|positive regulation of FGFR signaling pathway of ureteric bud formation|positive regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|positive regulation of FGF receptor signalling pathway of ureteric bud formation						yaf	2011-05-25T09:48:27Z						biological_process											owl:Class	
GO:0017080	biolink:NamedThing	sodium channel regulator activity	Binds to and modulates the activity of a sodium channel.	got7fsn_ti														molecular_function											owl:Class	
GO:0031448	biolink:NamedThing	positive regulation of fast-twitch skeletal muscle fiber contraction	Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction.	got7fsn_ti	positive regulation of fast-twitch skeletal muscle contraction|up regulation of fast-twitch skeletal muscle contraction|up-regulation of fast-twitch skeletal muscle contraction|activation of fast-twitch skeletal muscle contraction|stimulation of fast-twitch skeletal muscle contraction|upregulation of fast-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:1905724	biolink:NamedThing	positive regulation of trypanothione biosynthetic process	Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process.	got7fsn_ti	up regulation of trypanothione biosynthetic process|activation of trypanothione anabolism|up-regulation of trypanothione biosynthetic process|up-regulation of trypanothione anabolism|positive regulation of trypanothione biosynthesis|upregulation of trypanothione biosynthesis|activation of trypanothione biosynthesis|activation of trypanothione formation|up regulation of trypanothione anabolism|up regulation of trypanothione biosynthesis|up regulation of trypanothione synthesis|up-regulation of trypanothione synthesis|positive regulation of trypanothione anabolism|activation of trypanothione synthesis|up-regulation of trypanothione formation|activation of trypanothione biosynthetic process|up regulation of trypanothione formation|up-regulation of trypanothione biosynthesis|upregulation of trypanothione anabolism|positive regulation of trypanothione formation|upregulation of trypanothione synthesis|upregulation of trypanothione formation|positive regulation of trypanothione synthesis|upregulation of trypanothione biosynthetic process						rz	2016-11-25T14:44:50Z						biological_process											owl:Class	
GO:0042200	biolink:NamedThing	cyanuric acid catabolic process	The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides.	got7fsn_ti	cyanuric acid breakdown|cyanuric acid catabolism|cyanuric acid degradation											UM-BBD_pathwayID:cya		biological_process											owl:Class	
GO:0004283	biolink:NamedThing	obsolete plasmin activity	OBSOLETE. Catalysis of the preferential cleavage of Lys-Xaa > Arg-Xaa; higher selectivity than trypsin. Converts fibrin into soluble products.	got7fsn_ti	thrombolysin|fibrinolysin activity|actase activity|serum tryptase activity|plasmin activity|fibrinase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0072705	biolink:NamedThing	cellular response to mercaptoethanol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.	got7fsn_ti	cellular response to 2-sulfanylethanol						mah	2012-04-11T03:27:40Z						biological_process											owl:Class	
GO:1901959	biolink:NamedThing	positive regulation of cutin biosynthetic process	Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process.	got7fsn_ti	positive regulation of cutin formation|up regulation of cutin biosynthesis|up-regulation of cutin synthesis|upregulation of cutin biosynthetic process|positive regulation of cutin anabolism|up regulation of cutin synthesis|activation of cutin synthesis|positive regulation of cutin synthesis|up-regulation of cutin biosynthetic process|positive regulation of cutin biosynthesis|upregulation of cutin anabolism|up-regulation of cutin anabolism|up regulation of cutin biosynthetic process|activation of cutin biosynthesis|up regulation of cutin anabolism|activation of cutin biosynthetic process|upregulation of cutin formation|upregulation of cutin biosynthesis|up regulation of cutin formation|activation of cutin anabolism|activation of cutin formation|up-regulation of cutin formation|up-regulation of cutin biosynthesis|upregulation of cutin synthesis						tb	2013-02-19T19:06:19Z						biological_process											owl:Class	
GO:1903626	biolink:NamedThing	positive regulation of DNA catabolic process	Any process that activates or increases the frequency, rate or extent of DNA catabolic process.	got7fsn_ti	upregulation of DNA breakdown|activation of DNA catabolism|positive regulation of DNA catabolism|activation of DNA breakdown|upregulation of DNA catabolic process|up regulation of DNA catabolism|positive regulation of DNA breakdown|upregulation of DNA catabolism|up regulation of DNA breakdown|up-regulation of DNA catabolism|up-regulation of DNA degradation|up-regulation of DNA catabolic process|activation of DNA catabolic process|up regulation of DNA degradation|up regulation of DNA catabolic process|up-regulation of DNA breakdown|positive regulation of DNA degradation|upregulation of DNA degradation|activation of DNA degradation						sl	2014-11-19T22:36:51Z						biological_process											owl:Class	
GO:0000067	biolink:NamedThing	obsolete DNA replication and chromosome cycle	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DNA replication and chromosome cycle				This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful entity.	GO:0006260|GO:0007059|GO:0051276				True				biological_process											owl:Class	
GO:1990924	biolink:NamedThing	obsolete amphisome membrane	OBSOLETE. The lipid bilayer surrounding the amphisome and separating its contents from the cell cytoplasm.	got7fsn_ti	amphisomal membrane				This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2016-01-27T13:58:16Z		True				cellular_component											owl:Class	
GO:0060859	biolink:NamedThing	obsolete regulation of vesicle-mediated transport involved in floral organ abscission	OBSOLETE. Any process that modulates the rate, frequency, or extent of the directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.		dph	2009-08-12T03:56:21Z		True				biological_process											owl:Class	
GO:1905813	biolink:NamedThing	negative regulation of motor neuron axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance.	got7fsn_ti	downregulation of motor neuron axon guidance|inhibition of motor neuron axon guidance|down regulation of motoneuron axon guidance|down regulation of motor axon guidance|inhibition of motor axon pathfinding|down-regulation of motor neuron axon guidance|down-regulation of motoneuron axon guidance|negative regulation of motor axon guidance|downregulation of motoneuron axon guidance|down-regulation of motor axon guidance|down-regulation of motor axon pathfinding|inhibition of motor axon guidance|down regulation of motor axon pathfinding|downregulation of motor axon pathfinding|negative regulation of motor axon pathfinding|down regulation of motor neuron axon guidance|downregulation of motor axon guidance|negative regulation of motoneuron axon guidance|inhibition of motoneuron axon guidance						hbye	2017-01-12T13:25:21Z						biological_process											owl:Class	
GO:2000564	biolink:NamedThing	regulation of CD8-positive, alpha-beta T cell proliferation	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.	got7fsn_ti							ebc	2011-04-03T09:03:13Z						biological_process											owl:Class	
GO:0140543	biolink:NamedThing	positive regulation of piRNA transcription	Any process that increases the frequency, rate or extent of the synthesis of piRNA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19530					pg	2020-11-09T19:26:02Z						biological_process											owl:Class	
GO:0003750	biolink:NamedThing	obsolete cell cycle regulator	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cell cycle regulator			GO:0051726	This term was made obsolete because it does not represent a single molecular function.					True				molecular_function											owl:Class	
GO:1905579	biolink:NamedThing	negative regulation of ERBB3 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway.	got7fsn_ti	down-regulation of HER3 signaling pathway|downregulation of ERBB3 signalling pathway|negative regulation of HER3 signaling pathway|negative regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|down-regulation of ERBB3 signalling pathway|downregulation of ERBB3 signaling pathway|negative regulation of ERBB3 signalling pathway|inhibition of ERBB3 signaling pathway|down regulation of ERBB3 signaling pathway|down regulation of ERBB3 signalling pathway|inhibition of HER3 signaling pathway|down regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|downregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|downregulation of HER3 signaling pathway|down-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|inhibition of ERBB3 signalling pathway|down regulation of HER3 signaling pathway|inhibition of receptor tyrosine-protein kinase erbB-3 signaling pathway|down-regulation of ERBB3 signaling pathway						als	2016-10-19T11:47:03Z						biological_process											owl:Class	
GO:1990148	biolink:NamedThing	glutamate dehydrogenase complex	A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies.	got7fsn_ti	L-glutamate:NADP+ oxidoreductase (deaminating) complex|glutamate dehydrogenase (NADP+) complex|L-glutamate dehydrogenase complex|L-glutamic acid dehydrogenase complex|NAD(P)-glutamate dehydrogenase complex|dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) complex|glutamic acid dehydrogenase complex|glutamic dehydrogenase complex|NAD(P)H-dependent glutamate dehydrogenase complex						pr	2013-07-26T10:14:15Z						cellular_component											owl:Class	
GO:0002591	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.	got7fsn_ti	positive regulation of peptide antigen processing and presentation via MHC class I|up regulation of antigen processing and presentation of peptide antigen via MHC class I|upregulation of antigen processing and presentation of peptide antigen via MHC class I|up-regulation of antigen processing and presentation of peptide antigen via MHC class I|stimulation of antigen processing and presentation of peptide antigen via MHC class I|activation of antigen processing and presentation of peptide antigen via MHC class I													biological_process											owl:Class	
GO:0016910	biolink:NamedThing	obsolete SAP kinase 3 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	SAPK3|SAP kinase 3 activity				This term was made obsolete because it describes a gene product.	GO:0007254|GO:0004674				True				molecular_function											owl:Class	
GO:1900495	biolink:NamedThing	negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.	got7fsn_ti	down regulation of butyryl-CoA biosynthetic process from acetyl-CoA|downregulation of butyryl-CoA biosynthesis from acetyl-CoA|down-regulation of butyryl-CoA biosynthesis from acetyl-CoA|inhibition of butyryl-CoA biosynthetic process from acetyl-CoA|negative regulation of butyryl-CoA biosynthesis from acetyl-CoA|down-regulation of butyryl-CoA biosynthetic process from acetyl-CoA|downregulation of butyryl-CoA biosynthetic process from acetyl-CoA|inhibition of butyryl-CoA biosynthesis from acetyl-CoA|down regulation of butyryl-CoA biosynthesis from acetyl-CoA						tt	2012-05-02T03:51:49Z						biological_process											owl:Class	
GO:0033482	biolink:NamedThing	D-galacturonate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.	got7fsn_ti	D-galacturonate synthesis|D-galacturonate formation|D-galacturonate anabolism|D-galacturonate biosynthesis													biological_process											owl:Class	
GO:0030052	biolink:NamedThing	obsolete parvulin	OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin.	got7fsn_ti	parvulin			GO:0003755	This term was made obsolete because it describes a gene product.					True				molecular_function											owl:Class	
GO:0016143	biolink:NamedThing	S-glycoside metabolic process	The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.	got7fsn_ti	thioglycoside metabolism|thioglycoside metabolic process|S-glycoside metabolism													biological_process											owl:Class	
GO:0030329	biolink:NamedThing	prenylcysteine metabolic process	The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.	got7fsn_ti	prenylcysteine metabolism													biological_process											owl:Class	
GO:0055125	biolink:NamedThing	obsolete Nic96 complex	OBSOLETE. A protein complex that forms part of the nuclear pore complex, and is required for its correct assembly. In Saccharomyces cerevisiae Nic96 contains Nsp1p, Nup57p, Nup49p, and Nic96p.	got7fsn_ti	Nic96 complex					GO:0044612	jid	2009-10-12T08:35:18Z		True				cellular_component											owl:Class	
GO:0050027	biolink:NamedThing	obsolete L-idonate 2-dehydrogenase activity	OBSOLETE. Catalysis of the reaction: L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH.	got7fsn_ti	5-ketoglucono-idono-reductase activity|5-keto-D-gluconate 2-reductase activity|5KGR|L-idonate:NADP+ 2-oxidoreductase activity|L-idonate 2-dehydrogenase activity|5-ketogluconate 2-reductase activity|L-idonate dehydrogenase activity|reductase, 5-ketogluconate 5- (L-idonate-forming)				This term was made obsolete because EC:1.1.1.128 was deleted: the reaction described is covered by EC:1.1.1.264.	GO:0050572				True		MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN|RHEA:21176|EC:1.1.1.128		molecular_function											owl:Class	
GO:0005649	biolink:NamedThing	obsolete transportin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transportin|karyopherin-beta2				This term was made obsolete because it represents a single gene product and not a complex.	GO:0005634|GO:0005643|GO:0005737				True				cellular_component											owl:Class	
GO:0046473	biolink:NamedThing	phosphatidic acid metabolic process	The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.	got7fsn_ti	phosphatidic acid metabolism													biological_process											owl:Class	
GO:0034444	biolink:NamedThing	regulation of plasma lipoprotein oxidation	Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma.	got7fsn_ti	regulation of plasma lipoprotein particle oxidation													biological_process											owl:Class	
GO:0008163	biolink:NamedThing	obsolete DDT resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DDT resistance			GO:0046680	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0085009	biolink:NamedThing	obsolete interaction with host mediated by symbiont secreted substance released from Maurer's cleft	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via Maurer's cleft. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with host mediated by symbiont secreted substance released from Maurers cleft				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:08:39Z		True				biological_process											owl:Class	
GO:1904961	biolink:NamedThing	quiescent center organization	The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure.	got7fsn_ti	quiescent center structural organization						tb	2016-02-10T00:11:00Z						biological_process											owl:Class	
GO:0019514	biolink:NamedThing	obsolete lactose hydrolysis	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lactose hydrolysis				This term was made obsolete because hydrolysis is a reaction.	GO:0004565				True				biological_process											owl:Class	
PO:0000075	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015373	biolink:NamedThing	anion:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in).	got7fsn_ti	monovalent anion:sodium symporter activity													molecular_function											owl:Class	
GO:0009488	biolink:NamedThing	obsolete amicyanin	OBSOLETE. A copper-containing protein that acts as an electron carrier between methylamine dehydrogenase and cytochrome c.	got7fsn_ti	amicyanin			GO:0009055	This term was made obsolete because it does not represent a molecular function.					True				molecular_function											owl:Class	
GO:0070348	biolink:NamedThing	negative regulation of brown fat cell proliferation	Any process that stops or decreases the rate or extent of brown fat cell proliferation.	got7fsn_ti	down regulation of brown fat cell proliferation|downregulation of brown fat cell proliferation|down-regulation of brown fat cell proliferation|negative regulation of brown adipocyte proliferation|inhibition of brown fat cell proliferation|negative regulation of brown adipose cell proliferation													biological_process											owl:Class	
GO:0001191	biolink:NamedThing	obsolete transcriptional repressor activity, RNA polymerase II transcription factor binding	OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription factor binding transcription repressor activity|RNA polymerase II transcription repressor activity	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0061629|GO:0001227	krc	2011-08-25T02:12:30Z		True				molecular_function											owl:Class	
GO:0032429	biolink:NamedThing	regulation of phospholipase A2 activity	Any process that modulates the activity of the enzyme phospholipase A2.	got7fsn_ti														biological_process											owl:Class	
GO:0052442	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of defense-related symbiont JA-mediated signal transduction pathway by organism|modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0000114	biolink:NamedThing	obsolete regulation of transcription involved in G1 phase of mitotic cell cycle	OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G1 phase of the mitotic cell cycle.	got7fsn_ti	regulation of transcription involved in G1 phase of mitotic cell cycle|G1-specific transcription in mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during G1 phase of cell cycle				This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0000083|GO:0006357				True				biological_process											owl:Class	
GO:0046014	biolink:NamedThing	negative regulation of T cell homeostatic proliferation	Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.	got7fsn_ti	inhibition of T cell homeostatic proliferation|negative regulation of T-cell homeostatic proliferation|downregulation of T cell homeostatic proliferation|negative regulation of T lymphocyte homeostatic proliferation|down regulation of T cell homeostatic proliferation|down-regulation of T cell homeostatic proliferation|negative regulation of T-lymphocyte homeostatic proliferation|negative regulation of resting T cell proliferation													biological_process											owl:Class	
GO:0016650	biolink:NamedThing	obsolete oxidoreductase activity, acting on the CH-NH group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or similar compound, disulfide, NAD, NADP, oxygen or a flavin.	got7fsn_ti	oxidoreductase activity, acting on the CH-NH group of donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016645				True				molecular_function											owl:Class	
GO:1901896	biolink:NamedThing	positive regulation of ATPase-coupled calcium transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.	got7fsn_ti	positive regulation of calcium-translocating P-type ATPase activity|activation of calcium pump|up-regulation of sarcoplasmic reticulum ATPase|positive regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up-regulation of calcium transporting ATPase activity|up regulation of calcium ABC transporter|up-regulation of ATP phosphohydrolase (Ca2+-transporting)|upregulation of calcium transporting ATPase activity|positive regulation of calcium-transporting ATPase activity|positive regulation of Ca2+-pumping ATPase activity|upregulation of Ca2+-pumping ATPase activity|up regulation of calcium-translocating P-type ATPase activity|positive regulation of ATP phosphohydrolase (Ca2+-transporting)|up regulation of Ca(2+)-transporting ATPase activity|activation of Ca(2+)-transporting ATPase activity|up regulation of calcium pump|up regulation of calcium efflux ATPase|up-regulation of calcium-translocating P-type ATPase activity|upregulation of Ca(2+)-transporting ATPase activity|activation of calcium-translocating P-type ATPase activity|activation of sarcoplasmic reticulum ATPase|upregulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up regulation of calcium-transporting ATPase activity|positive regulation of calcium pump|up regulation of calcium transporting ATPase activity|positive regulation of plasma membrane Ca-ATPase|upregulation of calcium-transporting ATPase activity|upregulation of calcium efflux ATPase|up-regulation of Ca2+-pumping ATPase activity|activation of calcium ABC transporter|activation of calcium-transporting ATPase activity|activation of Ca2+-transporting ATPase activity|activation of ATP phosphohydrolase (Ca2+-transporting)|up regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|positive regulation of calcium transporting ATPase activity|up-regulation of Ca(2+)-transporting ATPase activity|up-regulation of calcium ABC transporter|up regulation of Ca2+-transporting ATPase activity|upregulation of Ca2+-transporting ATPase activity|up regulation of plasma membrane Ca-ATPase|upregulation of calcium pump|positive regulation of Ca(2+)-transporting ATPase activity|upregulation of calcium-translocating P-type ATPase activity|activation of Ca2+-pumping ATPase activity|up-regulation of calcium pump|positive regulation of calcium ABC transporter|activation of sarco(endo)plasmic reticulum Ca2+-ATPase|upregulation of sarcoplasmic reticulum ATPase|positive regulation of Ca2+-transporting ATPase activity|up-regulation of plasma membrane Ca-ATPase|upregulation of calcium ABC transporter|up-regulation of calcium-transporting ATPase activity|up-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up regulation of sarcoplasmic reticulum ATPase|activation of calcium efflux ATPase|up regulation of ATP phosphohydrolase (Ca2+-transporting)|activation of plasma membrane Ca-ATPase|up-regulation of calcium efflux ATPase|positive regulation of calcium efflux ATPase|activation of calcium transporting ATPase activity|upregulation of ATP phosphohydrolase (Ca2+-transporting)|up-regulation of Ca2+-transporting ATPase activity|up regulation of Ca2+-pumping ATPase activity|upregulation of plasma membrane Ca-ATPase|positive regulation of sarcoplasmic reticulum ATPase						rl	2013-02-06T21:18:29Z						biological_process											owl:Class	
GO:0033491	biolink:NamedThing	coniferin metabolic process	The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.	got7fsn_ti	coniferin metabolism											MetaCyc:PWY-116		biological_process											owl:Class	
GO:0048049	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070229	biolink:NamedThing	negative regulation of lymphocyte apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.	got7fsn_ti	down regulation of lymphocyte apoptosis|down-regulation of lymphocyte apoptosis|downregulation of lymphocyte apoptosis|negative regulation of lymphocyte apoptosis|inhibition of lymphocyte apoptosis				Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).									biological_process											owl:Class	
GO:1901073	biolink:NamedThing	glucosamine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines).	got7fsn_ti	glucosamines synthesis|glucosamine-containing compound synthesis|glucosamine-containing compound formation|glucosamine-containing compound biosynthesis|glucosamines anabolism|glucosamines biosynthetic process|glucosamine-containing compound anabolism|glucosamines formation|glucosamines biosynthesis						bf	2012-07-02T03:18:33Z						biological_process											owl:Class	
GO:0072702	biolink:NamedThing	response to methyl methanesulfonate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.	got7fsn_ti	response to MMS						mah	2012-04-11T03:04:12Z						biological_process											owl:Class	
GO:0061370	biolink:NamedThing	testosterone biosynthetic process	The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.	got7fsn_ti							dph	2010-10-27T02:50:48Z						biological_process											owl:Class	
GO:0006803	biolink:NamedThing	obsolete glutathione conjugation reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	glutathione conjugation reaction			GO:0004364	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:0072335	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	got7fsn_ti	regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation|regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation						mah	2010-11-03T03:12:38Z						biological_process											owl:Class	
GO:2000736	biolink:NamedThing	regulation of stem cell differentiation	Any process that modulates the frequency, rate or extent of stem cell differentiation.	got7fsn_ti							yaf	2011-06-14T02:05:16Z						biological_process											owl:Class	
GO:0023016	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000812	biolink:NamedThing	regulation of barbed-end actin filament capping	Any process that modulates the frequency, rate or extent of barbed-end actin filament capping.	got7fsn_ti	regulation of barbed-end F-actin capping activity|regulation of barbed-end actin capping activity|regulation of plus-end F-actin capping activity|regulation of plus-end actin filament capping activity						rl	2011-07-07T04:08:13Z						biological_process											owl:Class	
GO:0075050	biolink:NamedThing	obsolete positive regulation of symbiont cell wall strengthening involved in entry into host	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont cell wall strengthening during entry into host				The reason for the obsoletion is that there is no evidence that those processes exist.					True				biological_process											owl:Class	
GO:0060583	biolink:NamedThing	regulation of actin cortical patch localization	Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.	got7fsn_ti	regulation of actin cortical patch localisation						dph	2009-05-08T01:58:42Z						biological_process											owl:Class	
GO:0052709	biolink:NamedThing	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process	The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.	got7fsn_ti	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine synthesis|histidine betaine biosynthetic process|hercynine anabolism|histidine betaine formation|histidine betaine anabolism|hercynine formation|hercynine biosynthesis|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis|histidine betaine synthesis|hercynine biosynthetic process|hercynine synthesis|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine formation|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine anabolism|histidine betaine biosynthesis						ai	2011-08-05T02:22:05Z						biological_process											owl:Class	
GO:1902683	biolink:NamedThing	regulation of receptor localization to synapse	Any process that modulates the frequency, rate or extent of receptor localization to synapse.	got7fsn_ti	regulation of receptor localisation to synapse						kmv	2014-02-07T17:38:31Z						biological_process											owl:Class	
GO:1900711	biolink:NamedThing	negative regulation of tensidol B biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process.	got7fsn_ti	down-regulation of tensidol B anabolism|inhibition of tensidol B biosynthetic process|negative regulation of tensidol B anabolism|down regulation of tensidol B formation|down regulation of tensidol B anabolism|downregulation of tensidol B synthesis|negative regulation of tensidol B biosynthesis|down regulation of tensidol B biosynthetic process|inhibition of tensidol B synthesis|down regulation of tensidol B biosynthesis|downregulation of tensidol B biosynthesis|inhibition of tensidol B anabolism|downregulation of tensidol B biosynthetic process|down-regulation of tensidol B formation|downregulation of tensidol B anabolism|inhibition of tensidol B biosynthesis|down-regulation of tensidol B biosynthesis|inhibition of tensidol B formation|down-regulation of tensidol B synthesis|down-regulation of tensidol B biosynthetic process|negative regulation of tensidol B formation|down regulation of tensidol B synthesis|negative regulation of tensidol B synthesis|downregulation of tensidol B formation						di	2012-05-22T05:03:16Z						biological_process											owl:Class	
GO:1903818	biolink:NamedThing	positive regulation of voltage-gated potassium channel activity	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity.	got7fsn_ti	activation of voltage-sensitive potassium channel|up regulation of voltage gated potassium channel activity|up-regulation of voltage-gated potassium ion channel activity|up-regulation of voltage gated potassium channel activity|up regulation of voltage-gated potassium ion channel activity|upregulation of voltage gated potassium channel activity|positive regulation of voltage-gated potassium ion channel activity|up regulation of voltage-gated potassium channel activity|up regulation of voltage-sensitive potassium channel|upregulation of voltage-dependent potassium channel activity|up-regulation of voltage-gated potassium channel activity|positive regulation of voltage-sensitive potassium channel|activation of voltage-gated potassium ion channel activity|activation of voltage-dependent potassium channel activity|upregulation of voltage-gated potassium channel activity|activation of voltage gated potassium channel activity|upregulation of voltage-gated potassium ion channel activity|positive regulation of voltage gated potassium channel activity|up regulation of voltage-dependent potassium channel activity|up-regulation of voltage-sensitive potassium channel|activation of voltage-gated potassium channel activity|up-regulation of voltage-dependent potassium channel activity|positive regulation of voltage-dependent potassium channel activity|upregulation of voltage-sensitive potassium channel						sl	2015-01-16T17:22:18Z						biological_process											owl:Class	
GO:1902623	biolink:NamedThing	negative regulation of neutrophil migration	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration.	got7fsn_ti	inhibition of neutrophil migration|downregulation of neutrophil migration|down-regulation of neutrophil migration|down regulation of neutrophil migration						sl	2014-01-15T18:58:49Z						biological_process											owl:Class	
GO:0030391	biolink:NamedThing	fructosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.	got7fsn_ti	fructosamine biosynthesis|fructosamine anabolism|fructosamine synthesis|fructosamine formation													biological_process											owl:Class	
GO:1900527	biolink:NamedThing	obsolete regulation of nucleus size involved in G1 to G0 transition	OBSOLETE. Any regulation of nucleus size that is involved in G1 to G0 transition.	got7fsn_ti	regulation of nuclear volume involved in establishment of cell quiescence|regulation of nucleus size involved in cell cycle quiescence|regulation of nuclear size involved in G1 to G0 transition|regulation of nuclear volume involved in G1 to G0 transition|regulation of nuclear volume involved in stationary phase|regulation of nucleus size involved in establishment of cell quiescence|regulation of nucleus size involved in G1/G0 transition|regulation of nucleus size involved in G1 to G0 transition|regulation of nuclear size involved in G1/G0 transition|regulation of nuclear volume involved in cell cycle quiescence|regulation of nuclear size involved in cell cycle quiescence|regulation of nuclear volume involved in G1/G0 transition|regulation of nucleus size involved in stationary phase|regulation of nuclear size involved in stationary phase|regulation of nuclear size involved in establishment of cell quiescence				This term was made obsolete because it represents a phenotype.		al	2012-05-08T10:39:01Z		True				biological_process											owl:Class	
GO:0000020	biolink:NamedThing	obsolete negative regulation of recombination within rDNA repeats	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.	got7fsn_ti	negative regulation of recombination within rDNA repeats				This term was made obsolete because it describes a substrate-specific process.	GO:0045950				True				biological_process											owl:Class	
GO:0034112	biolink:NamedThing	positive regulation of homotypic cell-cell adhesion	Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.	got7fsn_ti														biological_process											owl:Class	
GO:1905495	biolink:NamedThing	positive regulation of G-quadruplex DNA binding	Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding.	got7fsn_ti	positive regulation of quadruplex DNA binding|upregulation of G quartet DNA binding|positive regulation of G quartet DNA binding|upregulation of quadruplex DNA binding|upregulation of G-DNA binding|activation of tetraplex DNA binding|upregulation of G quadruplex DNA binding|up-regulation of G-quartet DNA binding|up regulation of G quartet DNA binding|up-regulation of G quartet DNA binding|up-regulation of G-quadruplex DNA binding|activation of G quartet DNA binding|up regulation of G quadruplex DNA binding|up regulation of G-quartet DNA binding|positive regulation of G-quartet DNA binding|up-regulation of quadruplex DNA binding|up-regulation of G quadruplex DNA binding|positive regulation of G-DNA binding|up regulation of quadruplex DNA binding|activation of quadruplex DNA binding|positive regulation of G quadruplex DNA binding|up regulation of G-quadruplex DNA binding|up regulation of tetraplex DNA binding|upregulation of tetraplex DNA binding|up-regulation of G-DNA binding|activation of G-quartet DNA binding|up regulation of G-DNA binding|upregulation of G-quadruplex DNA binding|activation of G-quadruplex DNA binding|up-regulation of tetraplex DNA binding|positive regulation of tetraplex DNA binding|activation of G-DNA binding|activation of G quadruplex DNA binding|upregulation of G-quartet DNA binding						ans	2016-09-26T14:53:37Z						biological_process											owl:Class	
GO:0090279	biolink:NamedThing	regulation of calcium ion import	Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.	got7fsn_ti	regulation of transmembrane calcium influx						tb	2010-02-08T05:11:20Z						biological_process											owl:Class	
GO:0035826	biolink:NamedThing	obsolete rubidium ion transport	OBSOLETE. The directed movement of rubidium ions (Rb+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	Rb+ transport|rubidium cation transport				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-04T02:53:27Z		True				biological_process											owl:Class	
GO:1900826	biolink:NamedThing	negative regulation of membrane depolarization during cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.	got7fsn_ti	downregulation of membrane depolarization during cardiac muscle cell action potential|down regulation of membrane depolarization during cardiac muscle cell action potential|down-regulation of membrane depolarization during of cardiac muscle cell action potential|inhibition of membrane depolarization during cardiac muscle cell action potential						rl	2012-06-06T04:15:40Z						biological_process											owl:Class	
GO:0004205	biolink:NamedThing	obsolete caspase-8 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	caspase-8 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0060907	biolink:NamedThing	positive regulation of macrophage cytokine production	Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti							dph	2009-09-04T02:32:18Z						biological_process											owl:Class	
GO:0002310	biolink:NamedThing	alpha-beta T cell proliferation involved in immune response	The expansion of an alpha-beta T cell population by cell division as part of an immune response.	got7fsn_ti	alpha-beta T-lymphocyte proliferation during immune response|alpha-beta T cell proliferation during immune response|alpha-beta T-cell proliferation during immune response|alpha-beta T lymphocyte proliferation during immune response													biological_process											owl:Class	
GO:1900709	biolink:NamedThing	positive regulation of tensidol A biosynthetic process	Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process.	got7fsn_ti	up-regulation of tensidol A biosynthesis|upregulation of tensidol A anabolism|up-regulation of tensidol A synthesis|upregulation of tensidol A formation|up regulation of tensidol A biosynthesis|activation of tensidol A biosynthetic process|activation of tensidol A formation|upregulation of tensidol A biosynthetic process|up-regulation of tensidol A formation|upregulation of tensidol A synthesis|up regulation of tensidol A synthesis|activation of tensidol A synthesis|up regulation of tensidol A anabolism|up-regulation of tensidol A biosynthetic process|up regulation of tensidol A biosynthetic process|positive regulation of tensidol A formation|activation of tensidol A anabolism|positive regulation of tensidol A biosynthesis|activation of tensidol A biosynthesis|up regulation of tensidol A formation|up-regulation of tensidol A anabolism|positive regulation of tensidol A anabolism|upregulation of tensidol A biosynthesis|positive regulation of tensidol A synthesis						di	2012-05-22T05:02:12Z						biological_process											owl:Class	
GO:0006748	biolink:NamedThing	lipoamide metabolic process	The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.	got7fsn_ti	lipoamide metabolism													biological_process											owl:Class	
GO:0052142	biolink:NamedThing	obsolete chemotaxis within host	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0030147	biolink:NamedThing	obsolete natriuresis	OBSOLETE. The process of renal sodium excretion.	got7fsn_ti	natriuresis				This term was made obsolete because its definition was inaccurate.	GO:0035815				True		Wikipedia:Natriuresis		biological_process											owl:Class	
GO:0008944	biolink:NamedThing	obsolete oligopeptidase A activity	OBSOLETE. Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5.	got7fsn_ti	68000-M signalpeptide hydrolase activity|oligopeptidase A activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1901458	biolink:NamedThing	negative regulation of response to acetate	Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate.	got7fsn_ti	down regulation of response to acetate|inhibition of response to acetate|down-regulation of response to acetate|downregulation of response to acetate						tt	2012-10-02T14:26:15Z						biological_process											owl:Class	
GO:0044402	biolink:NamedThing	obsolete competition with other organism	OBSOLETE. Any process in which an organism within a multispecies community gains an advantage in growth or survival over another organism of a different species in that community.	got7fsn_ti	competition with another organism|interspecies competition	https://github.com/geneontology/go-ontology/issues/18568			This term was obsoleted because it is outside the scope of GO.					True				biological_process											owl:Class	
CHEBI:38184	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015809	biolink:NamedThing	arginine transport	The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-arginine transport													biological_process											owl:Class	
GO:1900176	biolink:NamedThing	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.	got7fsn_ti	down-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|downregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry						bf	2012-03-09T10:39:14Z						biological_process											owl:Class	
GO:2001045	biolink:NamedThing	negative regulation of integrin-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway.	got7fsn_ti	negative regulation of integrin-mediated signalling pathway						bf	2011-08-31T03:49:16Z						biological_process											owl:Class	
GO:1904427	biolink:NamedThing	positive regulation of calcium ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport.	got7fsn_ti	positive regulation of calcium ion membrane transport|up regulation of calcium ion transmembrane transport|up-regulation of calcium ion membrane transport|up-regulation of transmembrane calcium transport|activation of calcium ion membrane transport|activation of calcium ion transmembrane transport|upregulation of transmembrane calcium transport|upregulation of calcium ion transmembrane transport|up-regulation of calcium ion transmembrane transport|up regulation of transmembrane calcium transport|upregulation of calcium ion membrane transport|activation of transmembrane calcium transport|positive regulation of transmembrane calcium transport|up regulation of calcium ion membrane transport						sl	2015-07-02T20:44:25Z						biological_process											owl:Class	
GO:0002138	biolink:NamedThing	retinoic acid biosynthetic process	The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.	got7fsn_ti	retinoic acid anabolic process						hjd	2009-05-01T10:53:24Z						biological_process											owl:Class	
GO:0140542	biolink:NamedThing	regulation of piRNA transcription	Any process that modulates the frequency, rate or extent of the synthesis of a piRNA.	got7fsn_ti							pg	2020-11-09T19:08:15Z						biological_process											owl:Class	
GO:1904673	biolink:NamedThing	negative regulation of somatic stem cell population maintenance	Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance.	got7fsn_ti	inhibition of somatic stem cell population maintenance|downregulation of somatic stem cell population maintenance|down regulation of somatic stem cell population maintenance|down-regulation of somatic stem cell population maintenance						rph	2015-09-14T08:40:25Z						biological_process											owl:Class	
GO:1903248	biolink:NamedThing	regulation of citrulline biosynthetic process	Any process that modulates the frequency, rate or extent of citrulline biosynthetic process.	got7fsn_ti	regulation of citrulline anabolism|regulation of citrulline formation|regulation of citrulline synthesis|regulation of citrulline biosynthesis						rl	2014-08-04T15:24:34Z						biological_process											owl:Class	
GO:0120071	biolink:NamedThing	regulation of pyloric antrum smooth muscle contraction	Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction.	got7fsn_ti							krc	2017-06-13T23:32:39Z						biological_process											owl:Class	
GO:1902373	biolink:NamedThing	negative regulation of mRNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.	got7fsn_ti	negative regulation of mRNA decay|down-regulation of mRNA breakdown|downregulation of mRNA breakdown|inhibition of mRNA decay|downregulation of mRNA decay|downregulation of mRNA degradation|down-regulation of mRNA degradation|negative regulation of mRNA breakdown|negative regulation of mRNA catabolism|downregulation of mRNA catabolic process|downregulation of mRNA catabolism|inhibition of mRNA catabolism|down-regulation of mRNA catabolism|down-regulation of mRNA decay|inhibition of mRNA degradation|inhibition of mRNA breakdown|down regulation of mRNA catabolic process|down regulation of mRNA catabolism|down-regulation of mRNA catabolic process|inhibition of mRNA catabolic process|negative regulation of mRNA degradation|down regulation of mRNA decay|down regulation of mRNA breakdown|down regulation of mRNA degradation						bf	2013-08-22T15:16:19Z						biological_process											owl:Class	
UBERON:0001961	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900990	biolink:NamedThing	scopolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of scopolamine.	got7fsn_ti	scopolamine degradation|scopolamine catabolism|scopolamine breakdown						yaf	2012-06-14T09:48:00Z						biological_process											owl:Class	
GO:0016111	biolink:NamedThing	polyterpenoid metabolic process	The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units.	got7fsn_ti	polyterpene metabolism|polyterpenoid metabolism|polyterpene metabolic process													biological_process											owl:Class	
GO:0043937	biolink:NamedThing	regulation of sporulation	Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:1901513	biolink:NamedThing	lipo-chitin oligosaccharide transmembrane transporter activity	Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other.	got7fsn_ti							jl	2012-10-18T11:52:51Z						molecular_function											owl:Class	
GO:0060808	biolink:NamedThing	positive regulation of mesodermal to mesenchymal transition involved in gastrulation	Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.	got7fsn_ti							dph	2009-08-06T02:32:53Z						biological_process											owl:Class	
GO:0009669	biolink:NamedThing	sucrose:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in).	got7fsn_ti	sucrose:monovalent cation symporter activity|sucrose permease activity													molecular_function											owl:Class	
GO:1901411	biolink:NamedThing	negative regulation of tetrapyrrole biosynthetic process from glutamate	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.	got7fsn_ti	down-regulation of tetrapyrrole anabolism from glutamate|downregulation of tetrapyrrole biosynthetic process from glutamate|inhibition of tetrapyrrole biosynthetic process from glutamate|down-regulation of tetrapyrrole biosynthetic process from glutamate|negative regulation of tetrapyrrole formation from glutamate|downregulation of tetrapyrrole formation from glutamate|inhibition of tetrapyrrole anabolism from glutamate|negative regulation of tetrapyrrole biosynthesis from glutamate|down regulation of tetrapyrrole anabolism from glutamate|downregulation of tetrapyrrole biosynthesis from glutamate|down regulation of tetrapyrrole biosynthesis from glutamate|downregulation of tetrapyrrole anabolism from glutamate|down regulation of tetrapyrrole biosynthetic process from glutamate|down-regulation of tetrapyrrole biosynthesis from glutamate|inhibition of tetrapyrrole biosynthesis from glutamate|negative regulation of tetrapyrrole anabolism from glutamate|inhibition of tetrapyrrole formation from glutamate|negative regulation of tetrapyrrole synthesis from glutamate|inhibition of tetrapyrrole synthesis from glutamate|down regulation of tetrapyrrole formation from glutamate|down-regulation of tetrapyrrole synthesis from glutamate|down regulation of tetrapyrrole synthesis from glutamate|downregulation of tetrapyrrole synthesis from glutamate|down-regulation of tetrapyrrole formation from glutamate						tt	2012-10-01T16:22:03Z						biological_process											owl:Class	
GO:0120227	biolink:NamedThing	acyl-CoA binding	Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.	got7fsn_ti	acyl binding|acyl-coenzyme A binding	https://github.com/geneontology/go-ontology/issues/19243					krc	2020-05-19T16:06:24Z						molecular_function											owl:Class	
GO:0060123	biolink:NamedThing	regulation of growth hormone secretion	Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0009686	biolink:NamedThing	gibberellin biosynthetic process	The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.	got7fsn_ti	gibberellic acid anabolism|gibberellic acid biosynthesis|gibberellin biosynthesis|gibberellic acid biosynthetic process|gibberellic acid formation|gibberellic acid synthesis											MetaCyc:PWY-5036|MetaCyc:PWY-5035|MetaCyc:PWY-5070|MetaCyc:PWY-5052		biological_process											owl:Class	
GO:1901180	biolink:NamedThing	spheroidene biosynthetic process	The chemical reactions and pathways resulting in the formation of spheroidene.	got7fsn_ti	spheroidene biosynthesis|spheroidene formation|spheroidene anabolism|spheroidene synthesis						yaf	2012-07-19T09:49:22Z						biological_process											owl:Class	
GO:1903645	biolink:NamedThing	negative regulation of chaperone-mediated protein folding	Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding.	got7fsn_ti	down regulation of chaperone-mediated protein folding|inhibition of chaperone-mediated protein folding|downregulation of chaperone-mediated protein folding|down-regulation of chaperone-mediated protein folding						pga	2014-11-21T15:25:35Z						biological_process											owl:Class	
GO:1900690	biolink:NamedThing	negative regulation of gliotoxin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process.	got7fsn_ti	down regulation of gliotoxin anabolism|negative regulation of gliotoxin anabolism|down-regulation of gliotoxin anabolism|inhibition of gliotoxin synthesis|down-regulation of gliotoxin synthesis|down regulation of gliotoxin biosynthetic process|down-regulation of gliotoxin biosynthetic process|inhibition of gliotoxin biosynthetic process|inhibition of gliotoxin anabolism|negative regulation of gliotoxin formation|downregulation of gliotoxin formation|downregulation of gliotoxin anabolism|negative regulation of gliotoxin synthesis|downregulation of gliotoxin biosynthesis|inhibition of gliotoxin formation|inhibition of gliotoxin biosynthesis|down-regulation of gliotoxin biosynthesis|negative regulation of gliotoxin biosynthesis|down regulation of gliotoxin formation|down regulation of gliotoxin biosynthesis|downregulation of gliotoxin biosynthetic process|down-regulation of gliotoxin formation|down regulation of gliotoxin synthesis|downregulation of gliotoxin synthesis						di	2012-05-22T04:52:00Z						biological_process											owl:Class	
GO:0023036	biolink:NamedThing	obsolete initiation of signal transduction	OBSOLETE. The process in which a signal causes activation of a receptor, for example, via a conformation change.	got7fsn_ti	initiation of signal transduction|signal reception				This term was made obsolete because the meaning of the term is ambiguous. Note that this term was intended for the annotation of both ligands and receptors.	GO:0038023|GO:0048018|GO:0007165		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1900071	biolink:NamedThing	regulation of sulfite transport	Any process that modulates the frequency, rate or extent of sulfite transport.	got7fsn_ti	regulation of sulphite transport						dph	2012-01-26T08:41:10Z						biological_process											owl:Class	
GO:1901150	biolink:NamedThing	vistamycin metabolic process	The chemical reactions and pathways involving vistamycin.	got7fsn_ti	vistamycin metabolism|ribostamycin metabolism|ribostamycin metabolic process						yaf	2012-07-17T04:26:45Z						biological_process											owl:Class	
GO:0008552	biolink:NamedThing	obsolete zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity	OBSOLETE. Catalysis of the reaction: Me2+(in) + ATP = Me2+(out) + ADP + phosphate, where Me is Zn2+, Cd2+, Co2+, Ni2+ or Pb2+.	got7fsn_ti	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity				This term was made obsolete because it represents more than one molecular function.	GO:0005385|GO:0015662|GO:0015086|GO:0015087|GO:0015094|GO:0015099				True				molecular_function											owl:Class	
GO:0106115	biolink:NamedThing	negative regulation of mitotic cohesin dsDNA (leading strand) loading	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.	got7fsn_ti							hjd	2018-04-18T14:50:12Z						biological_process											owl:Class	
GO:0006128	biolink:NamedThing	obsolete oxidized glutathione reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	oxidized glutathione reduction				This term was made obsolete because the term string represents a molecular function and not a biological pathway.	GO:0006749|GO:0022900|GO:0004362				True				biological_process											owl:Class	
GO:0033470	biolink:NamedThing	gibberellin 12 biosynthetic process	The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.	got7fsn_ti	gibberellin A12 biosynthetic process|gibberellin 12 synthesis|gibberellin 12 formation|gibberellin 12 biosynthesis|gibberellin 12 anabolism|GA12 biosynthetic process											MetaCyc:PWY-5034		biological_process											owl:Class	
GO:0051926	biolink:NamedThing	negative regulation of calcium ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	inhibition of calcium ion transport|down-regulation of calcium ion transport|negative regulation of calcium transport|downregulation of calcium ion transport|down regulation of calcium ion transport													biological_process											owl:Class	
GO:0030401	biolink:NamedThing	obsolete transcription antiterminator activity	OBSOLETE. Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed.	got7fsn_ti	transcription antiterminator activity|transcriptional antiterminator activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001073|GO:0001072|GO:0006353				True				molecular_function											owl:Class	
GO:1901500	biolink:NamedThing	response to p-xylene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus.	got7fsn_ti							tt	2012-10-16T15:23:54Z						biological_process											owl:Class	
GO:0051148	biolink:NamedThing	negative regulation of muscle cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.	got7fsn_ti	downregulation of muscle cell differentiation|down regulation of muscle cell differentiation|down-regulation of muscle cell differentiation|inhibition of muscle cell differentiation													biological_process											owl:Class	
GO:2000561	biolink:NamedThing	regulation of CD4-positive, alpha-beta T cell proliferation	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.	got7fsn_ti							ebc	2011-04-03T09:01:04Z						biological_process											owl:Class	
GO:0006741	biolink:NamedThing	NADP biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH.	got7fsn_ti	nicotinamide adenine dinucleotide phosphate biosynthesis|NADP anabolism|oxidized NADP biosynthesis|oxidized NADP biosynthetic process|NADP (reduced) biosynthesis|oxidized nicotinamide adenine dinucleotide phosphate biosynthetic process|reduced NADP biosynthetic process|oxidized nicotinamide adenine dinucleotide phosphate biosynthesis|nicotinamide adenine dinucleotide phosphate biosynthetic process|reduced NADP biosynthesis|NADP (reduced) biosynthetic process|NADP formation|reduced nicotinamide adenine dinucleotide phosphate biosynthesis|NADP biosynthesis|NADP synthesis|NADPH biosynthesis|reduced nicotinamide adenine dinucleotide phosphate biosynthetic process|NADP (oxidized) biosynthetic process|NADP (oxidized) biosynthesis|NADPH biosynthetic process													biological_process											owl:Class	
GO:0140039	biolink:NamedThing	cell-cell adhesion in response to extracellular stimulus	The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus.	got7fsn_ti							pg	2017-05-24T11:37:30Z						biological_process											owl:Class	
GO:1902788	biolink:NamedThing	response to isooctane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.	got7fsn_ti							tt	2014-03-21T20:52:51Z						biological_process											owl:Class	
GO:1904704	biolink:NamedThing	positive regulation of protein localization to adherens junction	Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	got7fsn_ti	up-regulation of protein localisation in cell-cell adherens junction|up regulation of protein localisation in cell-cell adherens junction|activation of protein localisation in cell-cell adherens junction|up-regulation of protein localization to cell-cell adherens junction|activation of protein localization in cell-cell adherens junction|positive regulation of protein localisation to cell-cell adherens junction|up-regulation of protein localisation to cell-cell adherens junction|up regulation of protein localization to cell-cell adherens junction|up regulation of protein localization in cell-cell adherens junction|upregulation of protein localization to cell-cell adherens junction|upregulation of protein localisation in cell-cell adherens junction|activation of protein localization to cell-cell adherens junction|upregulation of protein localisation to cell-cell adherens junction|positive regulation of protein localisation in cell-cell adherens junction|positive regulation of protein localization in cell-cell adherens junction|activation of protein localisation to cell-cell adherens junction|up-regulation of protein localization in cell-cell adherens junction|up regulation of protein localisation to cell-cell adherens junction|upregulation of protein localization in cell-cell adherens junction						kmv	2015-10-01T15:12:02Z						biological_process											owl:Class	
GO:0009633	biolink:NamedThing	obsolete drought tolerance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	drought tolerance				This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process.	GO:0009819|GO:0009414				True				biological_process											owl:Class	
GO:1905516	biolink:NamedThing	positive regulation of fertilization	Any process that activates or increases the frequency, rate or extent of fertilization.	got7fsn_ti	upregulation of fertilization|positive regulation of syngamy|activation of fertilization|activation of syngamy|up regulation of syngamy|up regulation of fertilization|upregulation of syngamy|up-regulation of syngamy|up-regulation of fertilization						pr	2016-09-30T14:32:32Z						biological_process											owl:Class	
GO:1904140	biolink:NamedThing	negative regulation of microglial cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.	got7fsn_ti	down-regulation of microglial cell migration|inhibition of microglial cell migration|down regulation of microglial cell migration|downregulation of microglial cell migration						nc	2015-04-13T09:07:03Z						biological_process											owl:Class	
GO:1903910	biolink:NamedThing	negative regulation of receptor clustering	Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering.	got7fsn_ti	inhibition of receptor clustering|downregulation of receptor clustering|down-regulation of receptor clustering|down regulation of receptor clustering						als	2015-02-09T10:56:42Z						biological_process											owl:Class	
GO:2000910	biolink:NamedThing	negative regulation of sterol import	Any process that stops, prevents or reduces the frequency, rate or extent of sterol import.	got7fsn_ti	negative regulation of sterol uptake|negative regulation of sterol influx						bf	2011-07-29T01:25:14Z						biological_process											owl:Class	
GO:1905323	biolink:NamedThing	telomerase holoenzyme complex assembly	The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex.	got7fsn_ti	telomerase holoenzyme complex formation						mah	2016-07-18T10:38:14Z						biological_process											owl:Class	
GO:1903721	biolink:NamedThing	positive regulation of I-kappaB phosphorylation	Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation.	got7fsn_ti	up regulation of inhibitor of NF-kappaB phosphorylation|upregulation of I-kappaB phosphorylation|up regulation of IkappaB phosphorylation|up-regulation of IkappaB phosphorylation|activation of IkappaB phosphorylation|positive regulation of inhibitor of kappaB phosphorylation|activation of I-kappaB phosphorylation|activation of inhibitor of NF-kappaB phosphorylation|positive regulation of IKB phosphorylation|up regulation of inhibitor of kappaB phosphorylation|up-regulation of inhibitor of kappaB phosphorylation|activation of inhibitor of kappaB phosphorylation|upregulation of inhibitor of kappaB phosphorylation|up-regulation of inhibitor of NF-kappaB phosphorylation|positive regulation of IkappaB phosphorylation|upregulation of IkappaB phosphorylation|upregulation of inhibitor of NF-kappaB phosphorylation|up-regulation of I-kappaB phosphorylation|up regulation of IKB phosphorylation|upregulation of IKB phosphorylation|up regulation of I-kappaB phosphorylation|activation of IKB phosphorylation|positive regulation of inhibitor of NF-kappaB phosphorylation|up-regulation of IKB phosphorylation						lb	2014-12-08T15:45:25Z						biological_process											owl:Class	
GO:1900773	biolink:NamedThing	fumiquinazoline metabolic process	The chemical reactions and pathways involving fumiquinazoline.	got7fsn_ti	fumiquinazoline metabolism|fumiquinazolines metabolism|fumiquinazolines metabolic process						di	2012-06-04T09:29:22Z						biological_process											owl:Class	
GO:0003967	biolink:NamedThing	obsolete RNA-directed DNA polymerase, group II intron encoded	OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo.	got7fsn_ti	RNA-directed DNA polymerase, group II intron encoded			GO:0003964	This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'.					True				molecular_function											owl:Class	
GO:0098859	biolink:NamedThing	actin filament bundle of actin-based cell projection	A bundle of cross-linked actin filaments that is part of an actin-based cell protrusion, in which filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which stabilizes the filaments.	got7fsn_ti														cellular_component											owl:Class	
GO:0031116	biolink:NamedThing	positive regulation of microtubule polymerization	Any process that activates or increases the frequency, rate or extent of microtubule polymerization.	got7fsn_ti	up-regulation of microtubule polymerization|upregulation of microtubule polymerization|activation of microtubule polymerization|stimulation of microtubule polymerization|up regulation of microtubule polymerization													biological_process											owl:Class	
GO:0046116	biolink:NamedThing	queuosine metabolic process	The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.	got7fsn_ti	queuosine metabolism													biological_process											owl:Class	
GO:0035951	biolink:NamedThing	obsolete positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of oligopeptide transport by up regulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by upregulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by stimulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by up-regulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by activation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by positive regulation of transcription from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
CHEBI:27922	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019635	biolink:NamedThing	2-aminoethylphosphonate catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine.	got7fsn_ti	2-aminoethylphosphonate degradation|2-aminoethylphosphonate catabolism|ciliatine catabolic process|2-phosphonoethylamine catabolism|ciliatine catabolism|2-aminoethylphosphonate breakdown|2-phosphonoethylamine catabolic process											MetaCyc:PHOSPHONOTASE-PWY		biological_process											owl:Class	
GO:0140339	biolink:NamedThing	phosphatidylglycerol transfer activity	Directly binding to phosphatidylglycerol and delivering it either to an acceptor molecule or to a specific location.	got7fsn_ti	phosphatidylglycerol carrier activity						pg	2019-05-16T11:34:45Z						molecular_function											owl:Class	
GO:0070563	biolink:NamedThing	negative regulation of vitamin D receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.	got7fsn_ti	inhibition of vitamin D receptor signaling pathway|downregulation of vitamin D receptor signaling pathway|down regulation of vitamin D receptor signaling pathway|down-regulation of vitamin D receptor signaling pathway|negative regulation vitamin D receptor signalling pathway|negative regulation of VDR signalling pathway|negative regulation of VDR signaling pathway						mah	2009-04-14T01:59:21Z						biological_process											owl:Class	
GO:1901671	biolink:NamedThing	positive regulation of superoxide dismutase activity	Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.	got7fsn_ti	positive regulation of SOD-4|positive regulation of erythrocuprein|up regulation of superoxide:superoxide oxidoreductase activity|upregulation of superoxide:superoxide oxidoreductase activity|up regulation of erythrocuprein|positive regulation of Mn-SOD|up regulation of nickel superoxide oxidoreductase|positive regulation of Cu,Zn-SOD|positive regulation of nickel superoxide dismutase activity|positive regulation of hemocuprein|up-regulation of SODF|positive regulation of manganese superoxide dismutase activity|positive regulation of Mn, Fe superoxide dismutase|upregulation of SOD|up-regulation of hemocuprein|activation of manganese superoxide oxidoreductase|positive regulation of iron superoxide oxidoreductase|up-regulation of superoxide dismutase II|positive regulation of cytocuprein|up-regulation of erythrocuprein|activation of manganese superoxide dismutase activity|upregulation of SOD-2|positive regulation of Cu-Zn superoxide dismutase activity|activation of Cu,Zn-SOD|upregulation of Cu-Zn superoxide dismutase activity|positive regulation of cuprein|activation of ferrisuperoxide dismutase activity|activation of Fe-SOD|up-regulation of SOD-3|up regulation of zinc superoxide oxidoreductase|upregulation of hepatocuprein|upregulation of iron superoxide oxidoreductase|up-regulation of Fe-SOD|up-regulation of Mn-SOD|up regulation of cytocuprein|up regulation of ferrisuperoxide dismutase activity|upregulation of SODS|activation of SOD-4|up regulation of iron superoxide oxidoreductase|up-regulation of cytocuprein|upregulation of iron superoxide dismutase activity|positive regulation of superoxide:superoxide oxidoreductase activity|activation of cuprein|up regulation of superoxide dismutase II|up regulation of hepatocuprein|upregulation of Fe-SOD|up regulation of SOD-4|activation of copper, zinc superoxide dismutase activity|positive regulation of SOD-3|up-regulation of iron superoxide oxidoreductase|up-regulation of zinc superoxide oxidoreductase|positive regulation of SOD|up-regulation of SOD-2|up regulation of SODS|up-regulation of superoxide:superoxide oxidoreductase activity|up-regulation of manganese superoxide dismutase activity|activation of zinc superoxide oxidoreductase|activation of superoxide dismutase I|up-regulation of superoxide dismutase activity|activation of superoxide dismutase activity|up regulation of SOD-1|upregulation of Mn, Fe superoxide dismutase|positive regulation of superoxide dismutase I|up-regulation of Cu-Zn superoxide dismutase activity|positive regulation of SOD-1|up regulation of iron superoxide dismutase activity|upregulation of cytocuprein|activation of hepatocuprein|up regulation of nickel superoxide dismutase activity|activation of hemocuprein|positive regulation of copper, zinc superoxide dismutase activity|activation of SOD|activation of nickel superoxide oxidoreductase|up regulation of manganese superoxide dismutase activity|positive regulation of Fe-SOD|positive regulation of SODS|upregulation of SOD-3|positive regulation of SOD-2|up regulation of Mn-SOD|up-regulation of SOD|upregulation of Cu,Zn-SOD|up regulation of superoxide dismutase activity|upregulation of superoxide dismutase I|upregulation of nickel superoxide dismutase activity|activation of SOD-2|up regulation of hemocuprein|upregulation of cuprein|upregulation of zinc superoxide oxidoreductase|upregulation of nickel superoxide oxidoreductase|up-regulation of Mn, Fe superoxide dismutase|activation of superoxide:superoxide oxidoreductase activity|up-regulation of nickel superoxide oxidoreductase|activation of nickel superoxide dismutase activity|activation of SOD-3|activation of superoxide dismutase II|upregulation of manganese superoxide oxidoreductase|up-regulation of SODS|up-regulation of nickel superoxide dismutase activity|activation of SODF|activation of Mn, Fe superoxide dismutase|positive regulation of nickel superoxide oxidoreductase|upregulation of manganese superoxide dismutase activity|up regulation of Cu-Zn superoxide dismutase activity|activation of Cu-Zn superoxide dismutase activity|positive regulation of hepatocuprein|upregulation of SOD-1|up regulation of superoxide dismutase I|activation of iron superoxide oxidoreductase|up-regulation of SOD-1|up-regulation of hepatocuprein|up regulation of Cu,Zn-SOD|positive regulation of iron superoxide dismutase activity|positive regulation of zinc superoxide oxidoreductase|up regulation of Mn, Fe superoxide dismutase|positive regulation of superoxide dismutase II|upregulation of SODF|upregulation of erythrocuprein|up regulation of SOD-3|upregulation of copper, zinc superoxide dismutase activity|up-regulation of ferrisuperoxide dismutase activity|up-regulation of SOD-4|up regulation of Fe-SOD|activation of Mn-SOD|activation of erythrocuprein|up regulation of SOD|up regulation of manganese superoxide oxidoreductase|positive regulation of manganese superoxide oxidoreductase|upregulation of superoxide dismutase II|up regulation of SODF|positive regulation of SODF|activation of SODS|upregulation of superoxide dismutase activity|positive regulation of ferrisuperoxide dismutase activity|upregulation of SOD-4|upregulation of hemocuprein|activation of SOD-1|up-regulation of Cu,Zn-SOD|up regulation of copper, zinc superoxide dismutase activity|activation of iron superoxide dismutase activity|up-regulation of iron superoxide dismutase activity|up-regulation of cuprein|up regulation of SOD-2|up-regulation of superoxide dismutase I|up-regulation of manganese superoxide oxidoreductase|upregulation of Mn-SOD|activation of cytocuprein|upregulation of ferrisuperoxide dismutase activity|up-regulation of copper, zinc superoxide dismutase activity|up regulation of cuprein						tb	2012-11-21T21:36:11Z						biological_process											owl:Class	
GO:0030815	biolink:NamedThing	obsolete negative regulation of cAMP metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	negative regulation of 3',5'-cAMP metabolic process|negative regulation of 3',5' cAMP metabolism|down-regulation of cAMP metabolic process|downregulation of cAMP metabolic process|negative regulation of cyclic AMP metabolism|negative regulation of 3',5' cAMP metabolic process|negative regulation of 3',5'-cAMP metabolism|inhibition of cAMP metabolic process|negative regulation of cAMP metabolism|negative regulation of adenosine 3',5'-cyclophosphate metabolism|down regulation of cAMP metabolic process|negative regulation of adenosine 3',5'-cyclophosphate metabolic process|negative regulation of cyclic AMP metabolic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0098555	biolink:NamedThing	lumenal side of rough endoplasmic reticulum membrane	The side (leaflet) of the rough endoplasmic reticulum membrane that faces the lumen.	got7fsn_ti							dos	2013-12-03T12:13:24Z						cellular_component											owl:Class	
GO:1901782	biolink:NamedThing	p-cumate catabolic process	The chemical reactions and pathways resulting in the breakdown of p-cumate.	got7fsn_ti	p-cumate degradation|p-cumate catabolism|p-cumate breakdown						yaf	2013-01-16T10:40:32Z						biological_process											owl:Class	
GO:0010789	biolink:NamedThing	meiotic sister chromatid cohesion involved in meiosis I	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.	got7fsn_ti														biological_process											owl:Class	
CHEBI:45725	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901589	biolink:NamedThing	axon microtubule bundle	An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment.	got7fsn_ti	microtubule bundle of axon|axon microtubule fascicle|microtubule fascicle of axon						pr	2012-11-07T15:37:12Z				NIF_Subcellular:sao707332678		cellular_component											owl:Class	
CHEBI:25899	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904441	biolink:NamedThing	regulation of thyroid gland epithelial cell proliferation	Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation.	got7fsn_ti	regulation of thyroid follicular cell proliferation|regulation of Hurthle cell proliferation						sl	2015-07-06T15:41:09Z						biological_process											owl:Class	
GO:0007170	biolink:NamedThing	obsolete transmembrane receptor protein tyrosine kinase ligand binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transmembrane receptor protein tyrosine kinase ligand binding				This term was made obsolete because it represents a function rather than a process.	GO:0030971				True				biological_process											owl:Class	
GO:0021874	biolink:NamedThing	Wnt signaling pathway involved in forebrain neuroblast division	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.	got7fsn_ti	Wnt receptor signalling pathway in forebrain neuroblast division|Wnt-activated signaling pathway involved in forebrain neuroblast division|Wnt receptor signaling pathway involved in forebrain neuroblast division													biological_process											owl:Class	
GO:2000716	biolink:NamedThing	negative regulation of maintenance of mitotic sister chromatid cohesion, arms	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.	got7fsn_ti	negative regulation of maintenance of mitotic sister chromatin cohesion along arms|negative regulation of maintenance of sister chromatin cohesion along arms at mitosis						mah	2011-06-03T10:38:32Z						biological_process											owl:Class	
GO:1903001	biolink:NamedThing	negative regulation of lipid transport across blood-brain barrier	Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier.	got7fsn_ti	down-regulation of lipid transport across blood brain barrier|inhibition of lipid transport across blood brain barrier|down regulation of lipid transport across blood brain barrier|downregulation of lipid transport across blood brain barrier|negative regulation of lipid transport across blood brain barrier						sjp	2014-05-09T09:30:10Z						biological_process											owl:Class	
GO:0072095	biolink:NamedThing	regulation of branch elongation involved in ureteric bud branching	Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.	got7fsn_ti							mah	2010-02-10T01:41:18Z						biological_process											owl:Class	
GO:1903202	biolink:NamedThing	negative regulation of oxidative stress-induced cell death	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death.	got7fsn_ti	protection against oxidative stress-induced cell death|negative regulation of cell death in response to oxidative stress|down-regulation of cell death in response to oxidative stress|inhibition of cell death in response to oxidative stress|down regulation of cell death in response to oxidative stress|downregulation of cell death in response to oxidative stress						bf	2014-07-21T16:10:36Z						biological_process											owl:Class	
GO:1901294	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by negative regulation of DNA binding	OBSOLETE. Negative regulation of DNA binding that results in negative regulation of a SREBP signaling pathway.	got7fsn_ti	negative regulation of SREBP-mediated signalling pathway by negative regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by downregulation of DNA binding|negative regulation of SREBP signaling pathway by downregulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by inhibition of DNA binding|negative regulation of SREBP-mediated signaling pathway by negative regulation of DNA binding|negative regulation of SREBP signaling pathway by inhibition of DNA binding|inhibition of SREBP-dependent transcription by blocking DNA binding|negative regulation of SREBP-mediated signalling pathway by down-regulation of DNA binding|negative regulation of SREBP signaling pathway by down regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by inhibition of DNA binding|negative regulation of SREBP-mediated signaling pathway by down-regulation of DNA binding|negative regulation of SREBP signaling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by down regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by down regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by downregulation of DNA binding				The reason for obsoletion is that this term should be represented by a GO-CAM model.		bf	2012-08-20T14:11:03Z		True				biological_process											owl:Class	
GO:1901296	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.	got7fsn_ti	downregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|downregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|inhibition of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|inhibition of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment						vk	2012-08-21T09:06:52Z						biological_process											owl:Class	
GO:1904878	biolink:NamedThing	negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.	got7fsn_ti	negative regulation of generation of L-type calcium current|downregulation of generation of L-type calcium current|down regulation of generation of L-type calcium current|down-regulation of generation of L-type calcium current|inhibition of generation of L-type calcium current						sl	2015-12-18T22:30:37Z						biological_process											owl:Class	
GO:1902648	biolink:NamedThing	positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.	got7fsn_ti	activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis						di	2014-01-21T17:58:15Z						biological_process											owl:Class	
GO:0052452	biolink:NamedThing	obsolete modulation by organism of symbiont innate immunity	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of symbiont innate immune response|modulation by organism of symbiont innate immunity				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0003717	biolink:NamedThing	obsolete RNA polymerase II transcription termination factor activity	OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase II.	got7fsn_ti	RNA polymerase II transcription termination factor activity|Pol II transcription termination factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006369				True				molecular_function											owl:Class	
GO:0005357	biolink:NamedThing	obsolete constitutive glucose:proton symporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	got7fsn_ti	constitutive hydrogen:glucose transporter activity|constitutive hydrogen:glucose symporter activity|constitutive hydrogen/glucose transporter activity				The reason for obsoletion is that the constitutive aspect of the transporter is unlikely to be an aspect of the activity, but instead it probably relates to the expression level of the transporter.					True				molecular_function											owl:Class	
GO:1901447	biolink:NamedThing	positive regulation of response to propan-1-ol	Any process that activates or increases the frequency, rate or extent of response to propan-1-ol.	got7fsn_ti	activation of response to propan-1-ol|up regulation of response to propan-1-ol|upregulation of response to propan-1-ol|up-regulation of response to propan-1-ol						tt	2012-10-02T14:14:10Z						biological_process											owl:Class	
GO:0043460	biolink:NamedThing	obsolete response to long exposure to lithium ion	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a long or persistent exposure to a lithium ion stimulus.	got7fsn_ti	response to long exposure to lithium ion				This term was made obsolete because 'long' is not a quantitative or meaningful measurement of time.					True				biological_process											owl:Class	
GO:0033325	biolink:NamedThing	choline biosynthetic process via phosphoryl-ethanolamine	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine.	got7fsn_ti	choline anabolism via phosphoryl-ethanolamine|choline biosynthesis via phosphoryl-ethanolamine|choline synthesis via phosphoryl-ethanolamine|choline formation via phosphoryl-ethanolamine											MetaCyc:PWY-4762|MetaCyc:PWY-3385		biological_process											owl:Class	
GO:1904522	biolink:NamedThing	positive regulation of myofibroblast cell apoptotic process	Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process.	got7fsn_ti	upregulation of MFB apoptosis|positive regulation of myofibroblast cell apoptosis|up-regulation of myofibroblast cell apoptotic process|up regulation of myofibroblast cell apoptotic process|up-regulation of myofibroblast cell apoptosis|up regulation of myofibroblast cell apoptosis|upregulation of myofibroblast cell apoptotic process|activation of MFB apoptosis|positive regulation of MFB apoptosis|up regulation of MFB apoptotic process|up-regulation of MFB apoptosis|up regulation of MFB apoptosis|upregulation of MFB apoptotic process|activation of MFB apoptotic process|upregulation of myofibroblast cell apoptosis|activation of myofibroblast cell apoptosis|up-regulation of MFB apoptotic process|activation of myofibroblast cell apoptotic process|positive regulation of MFB apoptotic process						sl	2015-07-29T15:52:26Z						biological_process											owl:Class	
GO:0005810	biolink:NamedThing	obsolete endocytotic transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	endocytotic transport vesicle			GO:0030139	This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.					True				cellular_component											owl:Class	
GO:0060835	biolink:NamedThing	transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis.	got7fsn_ti	transforming growth factor receptor beta signalling pathway involved in oral/aboral axis specification						dph	2009-08-11T03:30:40Z						biological_process											owl:Class	
GO:0009230	biolink:NamedThing	thiamine catabolic process	The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.	got7fsn_ti	thiamin catabolic process|vitamin B1 catabolism|thiamine catabolism|vitamin B1 catabolic process|thiamine breakdown|thiamine degradation													biological_process											owl:Class	
GO:1905438	biolink:NamedThing	non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	Any non-canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.	got7fsn_ti	non-canonical Wnt receptor signalling pathway involved in mDA neuron differentiation|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|beta-catenin-independent Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt signaling pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt receptor signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|beta-catenin-independent Wnt receptor signaling pathway involved in mDA neuron differentiation|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt receptor signalling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt-activated signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation						bc	2016-09-14T15:52:22Z						biological_process											owl:Class	
GO:0072724	biolink:NamedThing	response to 4-nitroquinoline N-oxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.	got7fsn_ti							mah	2012-05-31T11:00:37Z						biological_process											owl:Class	
GO:0046006	biolink:NamedThing	regulation of activated T cell proliferation	Any process that modulates the frequency, rate or extent of activated T cell proliferation.	got7fsn_ti	regulation of activated T-lymphocyte proliferation|regulation of activated T lymphocyte proliferation|regulation of activated T-cell proliferation													biological_process											owl:Class	
GO:0001322	biolink:NamedThing	obsolete age-dependent response to oxidative stress involved in replicative cell aging	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.	got7fsn_ti	age-dependent response to oxidative stress during replicative cell ageing|age-dependent response to oxidative stress during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0002844	biolink:NamedThing	negative regulation of tolerance induction to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell.	got7fsn_ti	down regulation of tolerance induction to tumor cell|down-regulation of tolerance induction to tumor cell|downregulation of tolerance induction to tumor cell|negative regulation of tolerance induction to tumour cell|inhibition of tolerance induction to tumor cell													biological_process											owl:Class	
GO:0071509	biolink:NamedThing	obsolete activation of MAPKK activity involved in conjugation with cellular fusion	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of conjugation with cellular fusion.	got7fsn_ti	conjugation with cellular fusion, activation of MAP kinase kinase activity|activation of MAPKK activity involved in mating response|activation of MAP kinase kinase activity during conjugation with cellular fusion|conjugation with cellular fusion, activation of MAPKK activity	https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.		mah	2010-01-05T02:09:58Z		True				biological_process											owl:Class	
GO:0019415	biolink:NamedThing	acetate biosynthetic process from carbon monoxide	The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide.	got7fsn_ti	acetate formation from carbon monoxide|acetate anabolism from carbon monoxide|acetate synthesis from carbon monoxide|carbon monoxide dehydrogenase pathway													biological_process											owl:Class	
GO:0034411	biolink:NamedThing	cell wall (1->3)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.	got7fsn_ti	cell wall 1,3-beta-glucan biosynthetic process|cell wall beta-1,3-glucan anabolism|cell wall beta-1,3-glucan biosynthesis|cell wall beta-1,3-glucan synthesis|cell wall beta-1,3-glucan biosynthetic process|cell wall 1,3-beta-D-glucan biosynthetic process|cell wall 1,3-beta-glucan formation|cell wall 1,3-beta-glucan biosynthesis|cell wall 1,3-beta-glucan synthesis|cell wall beta-1,3-glucan formation|cell wall 1,3-beta-glucan anabolism													biological_process											owl:Class	
GO:0010686	biolink:NamedThing	tetracyclic triterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.	got7fsn_ti	tetracyclic triterpenoid biosynthesis													biological_process											owl:Class	
GO:1900215	biolink:NamedThing	negative regulation of apoptotic process involved in metanephric collecting duct development	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.	got7fsn_ti	inhibition of apoptosis of metanephric collecting duct development|down-regulation of apoptotic process involved in metanephric collecting duct development|down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development|downregulation of programmed cell death by apoptosis of metanephric collecting duct development|down-regulation of type I programmed cell death of metanephric collecting duct development|negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development|negative regulation of type I programmed cell death of metanephric collecting duct development|downregulation of apoptotic process involved in metanephric collecting duct development|down regulation of apoptotic cell death of metanephric collecting duct development|down-regulation of programmed cell death by apoptosis of metanephric collecting duct development|inhibition of programmed cell death by apoptosis of metanephric collecting duct development|inhibition of type I programmed cell death of metanephric collecting duct development|negative regulation of apoptotic program of metanephric collecting duct development|down regulation of apoptotic programmed cell death of metanephric collecting duct development|down-regulation of apoptotic process of metanephric collecting duct development|down-regulation of apoptotic cell death of metanephric collecting duct development|downregulation of apoptosis of metanephric collecting duct development|inhibition of apoptotic program of metanephric collecting duct development|down regulation of apoptotic program of metanephric collecting duct development|down regulation of apoptotic process of metanephric collecting duct development|down regulation of apoptotic process involved in metanephric collecting duct development|downregulation of type I programmed cell death of metanephric collecting duct development|negative regulation of apoptotic programmed cell death of metanephric collecting duct development|negative regulation of apoptotic cell death of metanephric collecting duct development|down regulation of signaling (initiator) caspase activity of metanephric collecting duct development|downregulation of signaling (initiator) caspase activity of metanephric collecting duct development|down-regulation of apoptotic programmed cell death of metanephric collecting duct development|downregulation of apoptotic program of metanephric collecting duct development|inhibition of apoptotic process of metanephric collecting duct development|inhibition of apoptotic cell death of metanephric collecting duct development|downregulation of apoptotic programmed cell death of metanephric collecting duct development|down regulation of type I programmed cell death of metanephric collecting duct development|down regulation of programmed cell death by apoptosis of metanephric collecting duct development|negative regulation of programmed cell death by apoptosis of metanephric collecting duct development|downregulation of apoptotic process of metanephric collecting duct development|inhibition of signaling (initiator) caspase activity of metanephric collecting duct development|down regulation of apoptosis of metanephric collecting duct development|inhibition of apoptotic process involved in metanephric collecting duct development|negative regulation of apoptosis of metanephric collecting duct development|inhibition of apoptotic programmed cell death of metanephric collecting duct development|down-regulation of apoptosis of metanephric collecting duct development|down-regulation of apoptotic program of metanephric collecting duct development|negative regulation of apoptotic process of metanephric collecting duct development|downregulation of apoptotic cell death of metanephric collecting duct development						yaf	2012-03-22T10:53:31Z						biological_process											owl:Class	
GO:0042099	biolink:NamedThing	obsolete gamma-delta T cell receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	gamma-delta T cell receptor activity				This term was made obsolete because it describes a receptor type, and not an activity.	GO:0032395|GO:0032394|GO:0042605				True				molecular_function											owl:Class	
GO:0035229	biolink:NamedThing	positive regulation of glutamate-cysteine ligase activity	Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate.	got7fsn_ti	up regulation of glutamate-cysteine ligase activity|up-regulation of glutamate-cysteine ligase activity|stimulation of glutamate-cysteine ligase activity|upregulation of glutamate-cysteine ligase activity|activation of glutamate-cysteine ligase activity													biological_process											owl:Class	
GO:0099180	biolink:NamedThing	zinc ion import into synaptic vesicle	The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle.	got7fsn_ti	zinc import into synaptic vesicle|Zn2+ import into synaptic vesicle													biological_process											owl:Class	
GO:0046062	biolink:NamedThing	dCDP metabolic process	The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate.	got7fsn_ti	dCDP metabolism													biological_process											owl:Class	
GO:1902192	biolink:NamedThing	2-methylbut-2-enoyl-CoA(4-) metabolic process	The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-).	got7fsn_ti	2-methylbut-2-enoyl-CoA(4-) metabolism						ms	2013-06-06T09:40:30Z						biological_process											owl:Class	
GO:2000001	biolink:NamedThing	regulation of DNA damage checkpoint	Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.	got7fsn_ti	regulation of DNA damage response, signal transduction resulting in cell cycle arrest						jl	2010-07-15T03:25:00Z						biological_process											owl:Class	
GO:1903526	biolink:NamedThing	negative regulation of membrane tubulation	Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation.	got7fsn_ti	down regulation of plasma membrane tubulation|down-regulation of plasma membrane tubulation|down regulation of membrane tubulation|inhibition of membrane tubulation|negative regulation of plasma membrane tubulation|downregulation of membrane tubulation|inhibition of plasma membrane tubulation|down-regulation of membrane tubulation|downregulation of plasma membrane tubulation						pm	2014-10-07T12:52:45Z						biological_process											owl:Class	
GO:1903423	biolink:NamedThing	positive regulation of synaptic vesicle recycling	Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling.	got7fsn_ti	up regulation of kiss-and-run synaptic vesicle recycling|upregulation of synaptic vesicle recycling|positive regulation of kiss-and-run synaptic vesicle recycling|up-regulation of kiss-and-stay synaptic vesicle recycling|positive regulation of kiss-and-stay synaptic vesicle recycling|upregulation of kiss-and-stay synaptic vesicle recycling|upregulation of kiss-and-run synaptic vesicle recycling|up regulation of synaptic vesicle recycling|up regulation of kiss-and-stay synaptic vesicle recycling|activation of synaptic vesicle recycling|activation of kiss-and-run synaptic vesicle recycling|up-regulation of kiss-and-run synaptic vesicle recycling|up-regulation of synaptic vesicle recycling|activation of kiss-and-stay synaptic vesicle recycling				An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype		pad	2014-09-09T15:28:07Z						biological_process											owl:Class	
GO:0019869	biolink:NamedThing	chloride channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a chloride channel.	got7fsn_ti														molecular_function											owl:Class	
GO:0030088	biolink:NamedThing	obsolete PSII associated light-harvesting complex II, core complex, LHCIId subcomplex	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	PSII associated light-harvesting complex II, core complex, LHCIId subcomplex			GO:0009655	This term was made obsolete because the 'complex' it refers to contains only one gene product.					True				cellular_component											owl:Class	
GO:0046163	biolink:NamedThing	heme C catabolic process	The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f.	got7fsn_ti	heme C degradation|heme C breakdown|haem C catabolic process|haem C catabolism|heme C catabolism													biological_process											owl:Class	
GO:0061085	biolink:NamedThing	regulation of histone H3-K27 methylation	Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.	got7fsn_ti							dph	2010-04-26T01:23:52Z						biological_process											owl:Class	
GO:0061476	biolink:NamedThing	response to anticoagulant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.	got7fsn_ti							dph	2012-11-07T09:07:00Z						biological_process											owl:Class	
GO:0100049	biolink:NamedThing	obsolete negative regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylcholine biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0006908	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900945	biolink:NamedThing	negative regulation of isoprene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process.	got7fsn_ti	negative regulation of hemiterpene metabolic process|down regulation of isoprene metabolic process|downregulation of isoprene metabolism|down regulation of hemiterpene metabolic process|inhibition of 2-methyl-1,3-butadiene metabolism|negative regulation of isoprene metabolism|negative regulation of hemiterpene metabolism|inhibition of hemiterpene metabolism|inhibition of 2-methyl-1,3-butadiene metabolic process|down-regulation of isoprene metabolism|down-regulation of isoprene metabolic process|downregulation of 2-methyl-1,3-butadiene metabolic process|down regulation of hemiterpene metabolism|down regulation of 2-methyl-1,3-butadiene metabolism|down regulation of isoprene metabolism|inhibition of hemiterpene metabolic process|down-regulation of hemiterpene metabolic process|inhibition of isoprene metabolism|down-regulation of hemiterpene metabolism|downregulation of 2-methyl-1,3-butadiene metabolism|downregulation of hemiterpene metabolic process|down-regulation of 2-methyl-1,3-butadiene metabolic process|downregulation of hemiterpene metabolism|inhibition of isoprene metabolic process|down-regulation of 2-methyl-1,3-butadiene metabolism|negative regulation of 2-methyl-1,3-butadiene metabolic process|downregulation of isoprene metabolic process|negative regulation of 2-methyl-1,3-butadiene metabolism|down regulation of 2-methyl-1,3-butadiene metabolic process						tt	2012-06-14T03:19:33Z						biological_process											owl:Class	
GO:0098547	biolink:NamedThing	lumenal side of Golgi membrane	The side of the Golgi membrane that faces the lumen.	got7fsn_ti							dos	2013-12-03T10:44:23Z						cellular_component											owl:Class	
GO:0042342	biolink:NamedThing	cyanogenic glycoside catabolic process	The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.	got7fsn_ti	cyanogenic glycoside catabolism|cyanogenic glycoside degradation|cyanogenic glycoside breakdown													biological_process											owl:Class	
GO:1901384	biolink:NamedThing	positive regulation of chorionic trophoblast cell proliferation	Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation.	got7fsn_ti	upregulation of chorionic trophoblast cell proliferation|up-regulation of chorionic trophoblast cell proliferation|up regulation of chorionic trophoblast cell proliferation|activation of chorionic trophoblast cell proliferation						vk	2012-10-01T10:04:41Z						biological_process											owl:Class	
GO:0001216	biolink:NamedThing	DNA-binding transcription activator activity	A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.	got7fsn_ti	transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription|bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding	https://github.com/geneontology/go-ontology/issues/16534|https://github.com/geneontology/go-ontology/issues/16736			For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2011-01-26T03:09:27Z			GO:0001140|GO:0001215			molecular_function											owl:Class	
GO:0009831	biolink:NamedThing	plant-type cell wall modification involved in multidimensional cell growth	The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana.	got7fsn_ti	cell wall modification during cell expansion|cellulose and pectin-containing cell wall modification during multidimensional cell growth													biological_process											owl:Class	
GO:0017175	biolink:NamedThing	obsolete IMP-GMP specific 5'-nucleotidase activity	OBSOLETE. Catalysis of the conversion of 5'-ribonucleotides to ribonucleosides and phosphate, with specificity for IMP or GMP 5'-ribonucleotides and H2O as a nucleophile.	got7fsn_ti	IMP-GMP specific 5'-nucleotidase activity				This term was made obsolete because it represents a gene product with two different activities.	GO:0050484				True				molecular_function											owl:Class	
GO:0016112	biolink:NamedThing	polyterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units.	got7fsn_ti	polyterpenoid synthesis|polyterpene biosynthetic process|polyterpenoid anabolism|polyterpene biosynthesis|polyterpenoid biosynthesis|polyterpenoid formation													biological_process											owl:Class	
GO:0071511	biolink:NamedThing	obsolete inactivation of MAPK activity involved in conjugation with cellular fusion	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of conjugation with cellular fusion.	got7fsn_ti	conjugation with cellular fusion, inactivation of MAPK activity|termination of MAPK activity during conjugation with cellular fusion|inactivation of MAPK activity involved in mating response|conjugation with cellular fusion, termination of MAPK activity	https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.		mah	2010-01-05T02:10:47Z		True				biological_process											owl:Class	
GO:1901862	biolink:NamedThing	negative regulation of muscle tissue development	Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.	got7fsn_ti	inhibition of muscle tissue development|down regulation of muscle tissue development|down-regulation of muscle tissue development|downregulation of muscle tissue development						yaf	2013-02-01T10:30:52Z						biological_process											owl:Class	
GO:1900203	biolink:NamedThing	obsolete positive regulation of spread of virus in host, cell to cell	OBSOLETE. Any process that activates or increases the frequency, rate or extent of spread of virus in host, cell to cell.	got7fsn_ti	upregulation of spread of virus in host, cell to cell|up-regulation of cell to cell spread of virus within host|up regulation of spread of virus within host, cell to cell|upregulation of spread of virus within host, cell to cell|positive regulation of spread of virus within host, cell to cell|positive regulation of viral spread within host, cell to cell|up regulation of cell to cell spread of virus within host|positive regulation of cell to cell spread of virus within host|activation of cell to cell spread of virus within host|up-regulation of spread of virus in host, cell to cell|up-regulation of spread of virus within host, cell to cell|activation of spread of virus within host, cell to cell|up-regulation of viral spread within host, cell to cell|activation of spread of virus in host, cell to cell|upregulation of cell to cell spread of virus within host|up regulation of viral spread within host, cell to cell|upregulation of viral spread within host, cell to cell|activation of viral spread within host, cell to cell|positive regulation of spread of virus in host, cell to cell|up regulation of spread of virus in host, cell to cell				This term was obsoleted at the TermGenie Gatekeeper stage.		pm	2012-03-21T01:16:00Z		True				biological_process											owl:Class	
GO:0008563	biolink:NamedThing	obsolete alpha-factor sex pheromone exporter	OBSOLETE. Catalysis of the reaction: ATP + H2O + alpha-factor(in) = ADP + phosphate + alpha-factor(out). The export of the alpha-factor sex pheromone by an ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that does not undergo phosphorylation during the transport process.	got7fsn_ti	alpha-factor-transporting ATPase|alpha-factor sex pheromone exporter				This term was made obsolete because this function does not exist; alpha-factor is secreted by the classical secretion pathway and not exported.					True				molecular_function											owl:Class	
GO:0005503	biolink:NamedThing	all-trans retinal binding	Binding to all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.	got7fsn_ti	visual yellow binding|xanthopsin|trans retinal binding|all-trans retinaldehyde binding|vitamin A binding													molecular_function											owl:Class	
GO:0046221	biolink:NamedThing	pyridine catabolic process	The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.	got7fsn_ti	pyridine catabolism|pyridine breakdown|pyridine degradation													biological_process											owl:Class	
GO:0009186	biolink:NamedThing	deoxyribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	deoxyribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:1905415	biolink:NamedThing	positive regulation of dense core granule exocytosis	Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis.	got7fsn_ti	up regulation of dense core granule exocytosis|up-regulation of dense core vesicle exocytosis|activation of dense core vesicle exocytosis|upregulation of dense core granule exocytosis|upregulation of dense core vesicle exocytosis|positive regulation of dense core vesicle exocytosis|activation of dense core granule exocytosis|up regulation of dense core vesicle exocytosis|up-regulation of dense core granule exocytosis						bf	2016-08-31T08:02:36Z						biological_process											owl:Class	
GO:0042574	biolink:NamedThing	retinal metabolic process	The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.	got7fsn_ti	retinal metabolism|retinaldehyde metabolism|retinaldehyde metabolic process													biological_process											owl:Class	
GO:1990872	biolink:NamedThing	obsolete negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that decreases the frequency, rate or extent of sterol import, by down regulation of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by negative regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by activation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by activation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by negative regulation of transcription from Pol II promoter|negative regulation of sterol import by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by negative regulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by activation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		rb	2015-09-28T21:22:23Z		True				biological_process											owl:Class	
GO:0043677	biolink:NamedThing	obsolete germination pore	OBSOLETE. A small pore in the outer wall of a mycelial spore through which the germ tube exits upon germination. It can be apical or eccentric in its location.	got7fsn_ti	germ pore				This term was made obsolete because it was poorly named and poorly defined.					True		Wikipedia:Germ_pore		cellular_component											owl:Class	
GO:2000684	biolink:NamedThing	negative regulation of cellular response to X-ray	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray.	got7fsn_ti	negative regulation of cellular response to X-ray radiation stimulus						yaf	2011-05-10T01:40:45Z						biological_process											owl:Class	
GO:1902966	biolink:NamedThing	positive regulation of protein localization to early endosome	Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.	got7fsn_ti	activation of protein localisation in early endosome|positive regulation of protein localisation to early endosome|upregulation of protein localization in early endosome|upregulation of protein localisation in early endosome|up regulation of protein localization in early endosome|activation of protein localisation to early endosome|up-regulation of protein localisation to early endosome|up regulation of protein localisation in early endosome|positive regulation of protein localisation in early endosome|up-regulation of protein localization in early endosome|up regulation of protein localisation to early endosome|up-regulation of protein localisation in early endosome|upregulation of protein localisation to early endosome|upregulation of protein localization to early endosome|activation of protein localization in early endosome|up regulation of protein localization to early endosome|positive regulation of protein localization in early endosome|activation of protein localization to early endosome|up-regulation of protein localization to early endosome						sjp	2014-05-06T09:28:30Z						biological_process											owl:Class	
GO:0034196	biolink:NamedThing	acylglycerol transport	The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids.	got7fsn_ti	glyceride transport													biological_process											owl:Class	
GO:1900745	biolink:NamedThing	positive regulation of p38MAPK cascade	Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.	got7fsn_ti	positive regulation of p38 cascade|up-regulation of p38 cascade|up regulation of p38MAPK cascade|up-regulation of p38MAPK cascade|up-regulation of p38 MAPK cascade|activation of p38 MAPK cascade|upregulation of p38 MAPK cascade|activation of p38MAPK cascade|up regulation of p38 MAPK cascade|positive regulation of p38 MAPK cascade|activation of p38 cascade|up regulation of p38 cascade|upregulation of p38MAPK cascade|upregulation of p38 cascade						pm	2012-05-28T02:40:48Z						biological_process											owl:Class	
GO:1903848	biolink:NamedThing	negative regulation of aorta morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis.	got7fsn_ti	down regulation of aorta morphogenesis|down-regulation of aorta morphogenesis|downregulation of aorta morphogenesis|inhibition of aorta morphogenesis						rph	2015-01-23T14:01:01Z						biological_process											owl:Class	
GO:1902684	biolink:NamedThing	negative regulation of receptor localization to synapse	Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse.	got7fsn_ti	downregulation of receptor localization to synapse|down-regulation of receptor localization to synapse|down-regulation of receptor localisation to synapse|inhibition of receptor localisation to synapse|inhibition of receptor localization to synapse|down regulation of receptor localization to synapse|negative regulation of receptor localisation to synapse|down regulation of receptor localisation to synapse|downregulation of receptor localisation to synapse						kmv	2014-02-07T17:38:41Z						biological_process											owl:Class	
GO:1901639	biolink:NamedThing	obsolete XDP catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of XDP.	got7fsn_ti	XDP degradation|XDP catabolism|XDP breakdown	https://github.com/geneontology/go-ontology/issues/20954			This term was obsoleted because there is no evidence that this reaction exist in vivo.		tb	2012-11-15T22:56:26Z		True				biological_process											owl:Class	
GO:1900288	biolink:NamedThing	regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.	got7fsn_ti	regulation of coenzyme F420-dependent nitroimidazole reduction|regulation of coenzyme F420-dependent nitroimidazole breakdown|regulation of coenzyme F420-dependent nitroreductase activity|regulation of coenzyme F420-dependent nitroimidazole catabolism						tt	2012-04-05T06:02:41Z						biological_process											owl:Class	
GO:0010692	biolink:NamedThing	regulation of alkaline phosphatase activity	Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.	got7fsn_ti														biological_process											owl:Class	
GO:0046362	biolink:NamedThing	ribitol biosynthetic process	The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.	got7fsn_ti	ribitol synthesis|ribitol anabolism|ribitol biosynthesis|ribitol formation													biological_process											owl:Class	
GO:0010503	biolink:NamedThing	obsolete negative regulation of cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that stops, prevents or reduces the frequency or rate of cell cycle arrest in response to nitrogen starvation.	got7fsn_ti					This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.					True				biological_process											owl:Class	
GO:0006572	biolink:NamedThing	tyrosine catabolic process	The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.	got7fsn_ti	tyrosine degradation|tyrosine breakdown|tyrosine catabolism													biological_process											owl:Class	
GO:1905526	biolink:NamedThing	regulation of Golgi lumen acidification	Any process that modulates the frequency, rate or extent of Golgi lumen acidification.	got7fsn_ti							dph	2016-10-05T13:16:25Z						biological_process											owl:Class	
GO:0033468	biolink:NamedThing	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.	got7fsn_ti	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthesis|CMP-KDO biosynthesis|CMP-keto-3-deoxy-D-manno-octulosonic acid synthesis|CMP-keto-3-deoxy-D-manno-octulosonic acid anabolism|CMP-ketodeoxyoctanoate biosynthetic process|CMP-keto-3-deoxy-D-manno-octulosonic acid formation|CMP-KDO biosynthetic process											MetaCyc:PWY-1269|MetaCyc:KDOSYN-PWY|MetaCyc:PWY-5111		biological_process											owl:Class	
GO:1900648	biolink:NamedThing	positive regulation of chanoclavine-I aldehyde biosynthetic process	Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.	got7fsn_ti	upregulation of chanoclavine-I aldehyde biosynthetic process|up regulation of chanoclavine-I aldehyde biosynthesis|up regulation of chanoclavine-I aldehyde synthesis|up-regulation of chanoclavine-I aldehyde formation|upregulation of chanoclavine-I aldehyde biosynthesis|up-regulation of chanoclavine-I aldehyde synthesis|up regulation of chanoclavine-I aldehyde anabolism|up regulation of chanoclavine-I aldehyde biosynthetic process|activation of chanoclavine-I aldehyde biosynthetic process|positive regulation of chanoclavine-I aldehyde synthesis|upregulation of chanoclavine-I aldehyde formation|upregulation of chanoclavine-I aldehyde synthesis|up-regulation of chanoclavine-I aldehyde biosynthesis|positive regulation of chanoclavine-I aldehyde biosynthesis|up regulation of chanoclavine-I aldehyde formation|upregulation of chanoclavine-I aldehyde anabolism|activation of chanoclavine-I aldehyde formation|up-regulation of chanoclavine-I aldehyde biosynthetic process|positive regulation of chanoclavine-I aldehyde anabolism|activation of chanoclavine-I aldehyde synthesis|up-regulation of chanoclavine-I aldehyde anabolism|positive regulation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde anabolism|activation of chanoclavine-I aldehyde biosynthesis						di	2012-05-22T04:05:06Z						biological_process											owl:Class	
GO:0072475	biolink:NamedThing	obsolete detection of stimulus involved in mitotic spindle checkpoint	OBSOLETE. The series of events in which information about whether the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle checkpoint.	got7fsn_ti	detection of stimulus involved in mitotic cell cycle spindle checkpoint|mitotic cell cycle spindle checkpoint sensor process|mitotic cell cycle spindle checkpoint sensor mechanism|sensing involved in mitotic cell cycle spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:49:55Z		True				biological_process											owl:Class	
UBERON:0002286	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000444	biolink:NamedThing	negative regulation of toll-like receptor 21 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 21 signalling pathway|negative regulation of TLR21 signaling pathway						bf	2011-03-04T10:32:29Z						biological_process											owl:Class	
GO:1905479	biolink:NamedThing	negative regulation of glutamate-ammonia ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate-ammonia ligase activity.	got7fsn_ti	inhibition of L-glutamate:ammonia ligase (ADP-forming)|inhibition of glutamate-ammonia ligase activity|inhibition of L-glutamine synthetase activity|down-regulation of L-glutamate:ammonia ligase (ADP-forming)|down-regulation of L-glutamine synthetase activity|downregulation of glutamylhydroxamic synthetase activity|downregulation of L-glutamate:ammonia ligase (ADP-forming)|inhibition of glutamylhydroxamic synthetase activity|down regulation of L-glutamine synthetase activity|negative regulation of glutamine synthetase activity|down-regulation of glutamine synthetase activity|negative regulation of glutamylhydroxamic synthetase activity|negative regulation of L-glutamate:ammonia ligase (ADP-forming)|down-regulation of glutamylhydroxamic synthetase activity|down regulation of glutamine synthetase activity|down regulation of glutamylhydroxamic synthetase activity|inhibition of glutamine synthetase activity|downregulation of glutamine synthetase activity|negative regulation of L-glutamine synthetase activity|downregulation of L-glutamine synthetase activity|downregulation of glutamate-ammonia ligase activity|down regulation of L-glutamate:ammonia ligase (ADP-forming)|down regulation of glutamate-ammonia ligase activity|down-regulation of glutamate-ammonia ligase activity						pga	2016-09-22T09:58:42Z						biological_process											owl:Class	
GO:0032095	biolink:NamedThing	regulation of response to food	Any process that modulates the frequency, rate or extent of a response to a food stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0032104	biolink:NamedThing	regulation of response to extracellular stimulus	Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:1904266	biolink:NamedThing	regulation of Schwann cell chemotaxis	Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis.	got7fsn_ti							sl	2015-05-28T17:47:41Z						biological_process											owl:Class	
GO:0080020	biolink:NamedThing	regulation of coenzyme A biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A.	got7fsn_ti														biological_process											owl:Class	
GO:0043457	biolink:NamedThing	regulation of cellular respiration	Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.	got7fsn_ti														biological_process											owl:Class	
GO:0098530	biolink:NamedThing	positive regulation of strand invasion	Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.	got7fsn_ti	positive regulation of D-loop biosynthesis|positive regulation of Rad51-mediated strand invasion|positive regulation of D-loop formation						dos	2013-10-16T12:15:59Z						biological_process											owl:Class	
GO:0033384	biolink:NamedThing	geranyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of geranyl diphosphate.	got7fsn_ti	geranyl diphosphate biosynthesis|geranyl diphosphate synthesis|geranyl diphosphate formation|geranyl diphosphate anabolism|geranyldiphosphate biosynthetic process											MetaCyc:PWY-5122		biological_process											owl:Class	
GO:0044033	biolink:NamedThing	obsolete multi-organism metabolic process	OBSOLETE. A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism.	got7fsn_ti	multi-organismal metabolism|multi-organism metabolism|multi-organismal metabolic process	https://github.com/geneontology/go-ontology/issues/19769			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1904743	biolink:NamedThing	negative regulation of telomeric DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding.	got7fsn_ti	downregulation of telomeric repeat binding|inhibition of telomere binding|down-regulation of telomere binding|inhibition of telomeric DNA binding|negative regulation of telomere binding|downregulation of telomere binding|inhibition of telomeric repeat binding|down regulation of telomeric repeat binding|down-regulation of telomeric repeat binding|down regulation of telomere binding|downregulation of telomeric DNA binding|down-regulation of telomeric DNA binding|down regulation of telomeric DNA binding|negative regulation of telomeric repeat binding						nc	2015-10-19T12:18:55Z						biological_process											owl:Class	
GO:0046291	biolink:NamedThing	obsolete 6-hydroxycineole biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.	got7fsn_ti	6-hydroxycineole anabolism|hydroxycineol biosynthetic process|hydroxycineol biosynthesis|6-endo-hydroxycineole biosynthesis|6-hydroxycineole formation|6-hydroxycineole biosynthesis|6-hydroxycineole biosynthetic process|6-hydroxycineole synthesis|6-endo-hydroxycineole biosynthetic process			GO:0019638	This term was made obsolete because 6-hydroxycineole is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0046143	biolink:NamedThing	obsolete positive regulation of coenzyme and prosthetic group metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups.	got7fsn_ti	positive regulation of coenzyme and prosthetic group metabolic process				This term was made obsolete because it was replaced by more specific terms.	GO:0051200				True				biological_process											owl:Class	
GO:1901517	biolink:NamedThing	aspyridone A catabolic process	The chemical reactions and pathways resulting in the breakdown of aspyridone A.	got7fsn_ti	aspyridone A breakdown|aspyridone A catabolism|aspyridone A degradation						di	2012-10-18T18:31:32Z						biological_process											owl:Class	
GO:0055124	biolink:NamedThing	obsolete premature neural plate formation	OBSOLETE. The formation of the neural plate before the appropriate time.	got7fsn_ti	premature neural plate formation									True				biological_process											owl:Class	
GO:0005373	biolink:NamedThing	obsolete heavy metal ion porter activity	OBSOLETE. A transporter of heavy metal ions that utilizes a carrier-mediated process to catalyze uniport, symport or antiport between aqueous phases on either side of a lipid membrane.	got7fsn_ti	heavy metal ion porter activity|metal ion transporter				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0015291|GO:0046873				True				molecular_function											owl:Class	
GO:2000234	biolink:NamedThing	positive regulation of rRNA processing	Any process that activates or increases the frequency, rate or extent of rRNA processing.	got7fsn_ti	positive regulation of 35S primary transcript processing						mah	2010-11-10T12:11:36Z						biological_process											owl:Class	
GO:1902201	biolink:NamedThing	negative regulation of bacterial-type flagellum-dependent cell motility	Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.	got7fsn_ti	down regulation of flagellin-based flagellar cell motility|inhibition of flagellin-based flagellar cell motility|negative regulation of flagellin-based flagellar cell motility|negative regulation of bacterial-type flagellar cell motility|down-regulation of bacterial-type flagellar cell motility|inhibition of bacterial-type flagellar cell motility|downregulation of bacterial-type flagellar cell motility|down regulation of bacterial-type flagellar cell motility|downregulation of flagellin-based flagellar cell motility|down-regulation of flagellin-based flagellar cell motility						jl	2013-06-06T14:58:41Z						biological_process											owl:Class	
GO:1901125	biolink:NamedThing	candicidin metabolic process	The chemical reactions and pathways involving candicidin.	got7fsn_ti	candicidin metabolism						yaf	2012-07-11T03:16:32Z						biological_process											owl:Class	
GO:0003901	biolink:NamedThing	obsolete DNA-directed RNA polymerase II activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).	got7fsn_ti	DNA-directed RNA polymerase II activity			GO:0003899	This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase II, core complex ; GO:0005665'.					True				molecular_function											owl:Class	
GO:0019295	biolink:NamedThing	coenzyme M biosynthetic process	The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.	got7fsn_ti	coenzyme M formation|coenzyme M synthesis|coenzyme M anabolism|coenzyme M biosynthesis											MetaCyc:P261-PWY		biological_process											owl:Class	
GO:0035330	biolink:NamedThing	regulation of hippo signaling	Any process that modulates the frequency, rate or extent of hippo signaling.	got7fsn_ti	regulation of hippo signalling cascade|regulation of hippo signaling cascade|regulation of hippo signaling pathway						bf	2010-02-26T10:53:05Z						biological_process											owl:Class	
GO:1904885	biolink:NamedThing	beta-catenin destruction complex assembly	The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex.	got7fsn_ti	Axin-APC-beta-catenin-GSK3B complex assembly|destruction complex formation|BDC formation|BDC assembly|beta-catenin degradation complex assembly|APC-Axin-1-beta-catenin complex formation|beta-catenin destruction complex formation|23S APC complex assembly|23S APC complex formation|beta-catenin degradation complex formation|Axin-APC-beta-catenin-GSK3B complex formation|APC-Axin-1-beta-catenin complex assembly						bf	2016-01-05T11:40:55Z						biological_process											owl:Class	
GO:1905886	biolink:NamedThing	obsolete chromatin remodeling involved in meiosis I	OBSOLETE. Any chromatin remodeling that is involved in meiosis I.	got7fsn_ti	meiosis-specific chromatin remodeling|chromatin modelling involved in meiosis I|chromatin remodelling involved in meiosis I|chromatin modeling involved in meiosis I	https://github.com/geneontology/go-ontology/issues/22036			This term was obsoleted because it represents a GO-CAM model.		mah	2017-01-31T14:29:00Z		True				biological_process											owl:Class	
GO:1900421	biolink:NamedThing	positive regulation of cellular alcohol catabolic process	Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process.	got7fsn_ti	up-regulation of cellular alcohol catabolic process|activation of cellular alcohol catabolic process|up regulation of cellular alcohol catabolic process|upregulation of cellular alcohol catabolic process						krc	2012-04-20T10:21:46Z						biological_process											owl:Class	
GO:1902653	biolink:NamedThing	secondary alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of secondary alcohol.	got7fsn_ti	secondary alcohol formation|secondary alcohol anabolism|secondary alcohol biosynthesis|secondary alcohol synthesis						tt	2014-01-22T10:15:02Z						biological_process											owl:Class	
GO:0019880	biolink:NamedThing	obsolete bacteriocin susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	bacteriocin susceptibility/resistance			GO:0046678	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0021918	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0021917				True				biological_process											owl:Class	
GO:1904827	biolink:NamedThing	negative regulation of hydrogen sulfide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process.	got7fsn_ti	down-regulation of hydrogen sulfide biosynthetic process|down-regulation of hydrogen sulfide biosynthesis|inhibition of hydrogen sulfide anabolism|downregulation of hydrogen sulfide formation|down regulation of hydrogen sulfide anabolism|downregulation of hydrogen sulfide synthesis|downregulation of hydrogen sulfide biosynthesis|down-regulation of hydrogen sulfide synthesis|negative regulation of hydrogen sulfide synthesis|down regulation of hydrogen sulfide biosynthesis|down regulation of hydrogen sulfide biosynthetic process|downregulation of hydrogen sulfide anabolism|inhibition of hydrogen sulphide biosynthetic process|down-regulation of hydrogen sulphide biosynthesis|negative regulation of hydrogen sulphide biosynthesis|inhibition of hydrogen sulfide biosynthetic process|inhibition of hydrogen sulfide synthesis|down-regulation of hydrogen sulfide anabolism|negative regulation of hydrogen sulfide anabolism|negative regulation of hydrogen sulphide biosynthetic process|down regulation of hydrogen sulphide biosynthesis|inhibition of hydrogen sulphide biosynthesis|down regulation of hydrogen sulphide biosynthetic process|down regulation of hydrogen sulfide formation|down regulation of hydrogen sulfide synthesis|down-regulation of hydrogen sulphide biosynthetic process|downregulation of hydrogen sulfide biosynthetic process|negative regulation of hydrogen sulfide formation|negative regulation of hydrogen sulfide biosynthesis|downregulation of hydrogen sulphide biosynthesis|downregulation of hydrogen sulphide biosynthetic process|down-regulation of hydrogen sulfide formation|inhibition of hydrogen sulfide formation|inhibition of hydrogen sulfide biosynthesis						rph	2015-11-24T10:15:34Z						biological_process											owl:Class	
GO:1900001	biolink:NamedThing	negative regulation of anthocyanin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process.	got7fsn_ti	negative regulation of anthocyanin breakdown|down regulation of anthocyanin degradation|negative regulation of anthocyanin catabolism|down regulation of anthocyanin catabolic process|negative regulation of anthocyanin degradation|down regulation of anthocyanin catabolism|down regulation of anthocyanin breakdown						tb	2011-12-20T07:12:11Z						biological_process											owl:Class	
GO:1901866	biolink:NamedThing	capsorubin biosynthetic process	The chemical reactions and pathways resulting in the formation of capsorubin.	got7fsn_ti	capsorubin anabolism|capsorubin biosynthesis|capsorubin formation|capsorubin synthesis						yaf	2013-02-04T10:50:26Z						biological_process											owl:Class	
GO:1901570	biolink:NamedThing	fatty acid derivative biosynthetic process	The chemical reactions and pathways resulting in the formation of fatty acid derivative.	got7fsn_ti	fatty acid derivative anabolism|fatty acid derivative synthesis|fatty acid derivative formation|fatty acid derivative biosynthesis						pr	2012-11-04T17:13:44Z						biological_process											owl:Class	
GO:0042454	biolink:NamedThing	ribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	ribonucleoside catabolism|ribonucleoside degradation|ribonucleoside breakdown													biological_process											owl:Class	
GO:0010100	biolink:NamedThing	negative regulation of photomorphogenesis	Any process that stops, reduces or prevents photomorphogenesis.	got7fsn_ti	down-regulation of photomorphogenesis|inhibition of photomorphogenesis|down regulation of photomorphogenesis|downregulation of photomorphogenesis													biological_process											owl:Class	
GO:0030818	biolink:NamedThing	obsolete negative regulation of cAMP biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	negative regulation of 3',5'-cAMP biosynthetic process|negative regulation of 3',5' cAMP biosynthetic process|negative regulation of adenosine 3',5'-cyclophosphate biosynthetic process|negative regulation of cAMP synthesis|negative regulation of cyclic AMP biosynthetic process|down regulation of cAMP biosynthetic process|negative regulation of adenosine 3',5'-cyclophosphate biosynthesis|downregulation of cAMP biosynthetic process|inhibition of cAMP biosynthetic process|negative regulation of cAMP biosynthesis|down-regulation of cAMP biosynthetic process|negative regulation of cAMP anabolism|negative regulation of 3',5' cAMP biosynthesis|negative regulation of cAMP formation|negative regulation of 3',5'-cAMP biosynthesis|negative regulation of cyclic AMP biosynthesis	https://github.com/geneontology/go-ontology/issues/14718			The reason for obsoletion is that the term represents a molecular function.					True				biological_process											owl:Class	
GO:0003435	biolink:NamedThing	smoothened signaling pathway involved in growth plate cartilage chondrocyte development	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that contributes to the progression of a growth plate cartilage chondrocyte over time.	got7fsn_ti	hedgehog signaling pathway involved in growth plate cartilage chondrocyte development|hh signaling pathway involved in growth plate cartilage chondrocyte development|smoothened signalling pathway involved in growth plate cartilage chondrocyte development						dph	2009-12-22T01:02:42Z						biological_process											owl:Class	
UBERON:0005079	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904408	biolink:NamedThing	melatonin binding	Binding to melatonin.	got7fsn_ti							mr	2015-06-25T19:19:53Z						molecular_function											owl:Class	
GO:2000937	biolink:NamedThing	negative regulation of cellotriose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process.	got7fsn_ti	negative regulation of cellotriose catabolism						tt	2011-08-01T12:45:31Z						biological_process											owl:Class	
GO:0019383	biolink:NamedThing	(+)-camphor catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone.	got7fsn_ti	(+)-camphor breakdown|(+)-camphor degradation|(+)-camphor catabolism											MetaCyc:P601-PWY		biological_process											owl:Class	
GO:0046156	biolink:NamedThing	siroheme metabolic process	The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.	got7fsn_ti	sirohaem metabolic process|sirohaem metabolism|siroheme metabolism													biological_process											owl:Class	
GO:1900435	biolink:NamedThing	obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.	got7fsn_ti	down regulation of filamentous growth of a population of unicellular organisms in response to starvation|inhibition of filamentous growth of a population of unicellular organisms in response to starvation|downregulation of filamentous growth of a population of unicellular organisms in response to starvation|down-regulation of filamentous growth of a population of unicellular organisms in response to starvation				This term was obsoleted because it represents a GO-CAM model.		di	2012-04-25T05:54:56Z		True				biological_process											owl:Class	
GO:2000992	biolink:NamedThing	negative regulation of galactomannan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process.	got7fsn_ti							tt	2011-08-08T03:16:00Z						biological_process											owl:Class	
GO:1902771	biolink:NamedThing	positive regulation of choline O-acetyltransferase activity	Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity.	got7fsn_ti	up regulation of acetyl-CoA:choline O-acetyltransferase activity|activation of acetyl-CoA:choline O-acetyltransferase activity|up regulation of choline acetyltransferase activity|up regulation of choline O-acetyltransferase activity|positive regulation of CHOACTase activity|up-regulation of choline acetylase activity|upregulation of choline O-acetyltransferase activity|activation of choline acetylase activity|up-regulation of choline O-acetyltransferase activity|positive regulation of choline acetyltransferase activity|upregulation of choline acetylase activity|up regulation of CHOACTase activity|upregulation of acetyl-CoA:choline O-acetyltransferase activity|up regulation of choline acetylase activity|activation of choline O-acetyltransferase activity|upregulation of CHOACTase activity|upregulation of choline acetyltransferase activity|activation of CHOACTase activity|activation of choline acetyltransferase activity|up-regulation of acetyl-CoA:choline O-acetyltransferase activity|up-regulation of choline acetyltransferase activity|up-regulation of CHOACTase activity|positive regulation of choline acetylase activity|positive regulation of acetyl-CoA:choline O-acetyltransferase activity						mr	2014-03-11T18:58:39Z						biological_process											owl:Class	
GO:0075234	biolink:NamedThing	obsolete zoospore movement on or near host	OBSOLETE. Any process involved in the directed movement of a zoospore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	zoospore motility on or near host				This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:1904958	biolink:NamedThing	positive regulation of midbrain dopaminergic neuron differentiation	Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation.	got7fsn_ti	upregulation of midbrain DA neurogenesis|up-regulation of midbrain dopaminergic neuron production|up regulation of DA neurogenesis from midbrain floor plate|upregulation of midbrain dopaminergic neuron differentiation|activation of mDA neuron differentiation|up-regulation of mDA neuron differentiation|up regulation of mDA neuron differentiation|positive regulation of midbrain DA neurogenesis|upregulation of midbrain dopaminergic neuron production|positive regulation of DA neurogenesis from midbrain floor plate|up-regulation of midbrain DA neurogenesis|up regulation of midbrain DA neurogenesis|activation of midbrain dopaminergic neuron production|upregulation of mDA neuron differentiation|positive regulation of mDA neuron differentiation|upregulation of DA neurogenesis from midbrain floor plate|activation of DA neurogenesis from midbrain floor plate|up-regulation of midbrain dopaminergic neuron differentiation|up regulation of midbrain dopaminergic neuron differentiation|activation of midbrain DA neurogenesis|up-regulation of DA neurogenesis from midbrain floor plate|positive regulation of midbrain dopaminergic neuron production|up regulation of midbrain dopaminergic neuron production|activation of midbrain dopaminergic neuron differentiation						bf	2016-02-09T12:00:36Z						biological_process											owl:Class	
GO:0010684	biolink:NamedThing	tricyclic triterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.	got7fsn_ti	tricyclic triterpenoid catabolism													biological_process											owl:Class	
GO:0042394	biolink:NamedThing	obsolete ecdysis, protein-based cuticle	OBSOLETE. The shedding of the old protein-based cuticular fragments during the molting cycle. Examples of this process are found in invertebrates.	got7fsn_ti	ecdysis, protein-based cuticle				This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0018990|GO:0042395				True				biological_process											owl:Class	
GO:0043268	biolink:NamedThing	positive regulation of potassium ion transport	Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	activation of potassium ion transport|upregulation of potassium ion transport|up regulation of potassium ion transport|positive regulation of potassium conductance|stimulation of potassium ion transport|positive regulation of potassium ion conductance|positive regulation of K+ conductance|up-regulation of potassium ion transport|positive regulation of K+ transport|positive regulation of potassium transport													biological_process											owl:Class	
GO:2000408	biolink:NamedThing	negative regulation of T cell extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation.	got7fsn_ti	negative regulation of T-lymphocyte extravasation|negative regulation of T-cell extravasation|negative regulation of T lymphocyte extravasation						mah	2011-02-23T10:52:28Z						biological_process											owl:Class	
GO:0033267	biolink:NamedThing	obsolete axon part	OBSOLETE. A part of an axon, a cell projection of a neuron.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0030424				True		NIF_Subcellular:sao280355188		cellular_component											owl:Class	
GO:1905542	biolink:NamedThing	negative regulation of L-arginine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane.	got7fsn_ti	negative regulation of L-arginine import into cell|down regulation of L-arginine import into cell|downregulation of L-arginine import into cell|inhibition of L-arginine import into cell						mah	2014-03-31T14:30:46Z			GO:1902827			biological_process											owl:Class	
GO:0035986	biolink:NamedThing	obsolete senescence-associated heterochromatin focus assembly	OBSOLETE. The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes.	got7fsn_ti	SAHF formation|senescence-associated heterochromatin foci formation|senescence-associated heterochromatin focus formation	https://github.com/geneontology/go-ontology/issues/22024			This term was obsoleted because there is no evidence that this is a distinct process; this should be captured as an extension	GO:0031507	bf	2011-08-25T04:43:56Z		True				biological_process											owl:Class	
GO:1905807	biolink:NamedThing	negative regulation of synapse pruning	Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning.	got7fsn_ti	regulation of synapse removal|regulation of synapse elimination|down regulation of synapse disassembly|regulation of synapse disassembly|downregulation of synapse disassembly|inhibition of synapse disassembly|regulation of synapse clearance|down-regulation of synapse disassembly						tb	2017-01-11T22:03:24Z						biological_process											owl:Class	
GO:0044376	biolink:NamedThing	obsolete RNA polymerase II complex import to nucleus	OBSOLETE. The directed movement of the DNA-directed RNA polymerase II core complex from the cytoplasm into the nucleus.	got7fsn_ti	DNA-directed RNA polymerase II core complex import into nucleus|DNA-directed RNA polymerase II core complex localization to nucleus|RNA polymerase II complex import into nucleus|RNA polymerase II complex localisation to nucleus				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606	jl	2011-12-01T04:43:03Z		True	GO:0098738			biological_process											owl:Class	
GO:1903665	biolink:NamedThing	negative regulation of asexual reproduction	Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.	got7fsn_ti	downregulation of asexual reproduction|down regulation of asexual reproduction|down-regulation of asexual reproduction|inhibition of asexual reproduction						pf	2014-11-26T21:13:32Z						biological_process											owl:Class	
GO:0018325	biolink:NamedThing	obsolete enzyme active site formation via S-phospho-L-cysteine	OBSOLETE. The transient phosphorylation of peptidyl-cysteine to form S-phospho-L-cysteine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:3142516 and PMID:22927394.					True		RESID:AA0034		biological_process											owl:Class	
GO:1900696	biolink:NamedThing	negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.	got7fsn_ti	negative regulation of N',N'',N'''-triacetylfusarinine C anabolism|negative regulation of N',N'',N'''-triacetylfusarinine C synthesis|down regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|down-regulation of N',N'',N'''-triacetylfusarinine C synthesis|down-regulation of N',N'',N'''-triacetylfusarinine C anabolism|down-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C biosynthetic process|downregulation of N',N'',N'''-triacetylfusarinine C formation|downregulation of N',N'',N'''-triacetylfusarinine C anabolism|inhibition of N',N'',N'''-triacetylfusarinine C formation|downregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|down regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|down regulation of N',N'',N'''-triacetylfusarinine C synthesis|down regulation of N',N'',N'''-triacetylfusarinine C anabolism|inhibition of N',N'',N'''-triacetylfusarinine C synthesis|down-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|negative regulation of N',N'',N'''-triacetylfusarinine C formation|negative regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C anabolism|down regulation of N',N'',N'''-triacetylfusarinine C formation|inhibition of N',N'',N'''-triacetylfusarinine C biosynthesis|downregulation of N',N'',N'''-triacetylfusarinine C biosynthesis|down-regulation of N',N'',N'''-triacetylfusarinine C formation|downregulation of N',N'',N'''-triacetylfusarinine C synthesis						di	2012-05-22T04:54:45Z						biological_process											owl:Class	
GO:1904007	biolink:NamedThing	positive regulation of phospholipase D activity	Any process that activates or increases the frequency, rate or extent of phospholipase D activity.	got7fsn_ti	upregulation of phosphatidylcholine phosphatidohydrolase activity|up regulation of phosphatidylcholine phosphatidohydrolase activity|activation of phosphatidylcholine phosphatidohydrolase activity|up-regulation of phospholipase D activity|activation of lipophosphodiesterase II activity|up-regulation of phosphatidylcholine phosphatidohydrolase activity|upregulation of lecithinase D activity|positive regulation of lecithinase D activity|activation of phospholipase D activity|up-regulation of choline phosphatase activity|up regulation of lecithinase D activity|activation of lecithinase D activity|up regulation of phospholipase D activity|upregulation of phospholipase D activity|positive regulation of choline phosphatase activity|up-regulation of lipophosphodiesterase II activity|positive regulation of phosphatidylcholine phosphatidohydrolase activity|activation of choline phosphatase activity|up regulation of lipophosphodiesterase II activity|upregulation of lipophosphodiesterase II activity|positive regulation of lipophosphodiesterase II activity|upregulation of choline phosphatase activity|up regulation of choline phosphatase activity|up-regulation of lecithinase D activity						sl	2015-03-06T17:20:17Z						biological_process											owl:Class	
GO:0006604	biolink:NamedThing	phosphoarginine metabolic process	The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates.	got7fsn_ti	phosphoarginine metabolism													biological_process											owl:Class	
GO:0046996	biolink:NamedThing	obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and the latter donor is dehydrogenated.	got7fsn_ti	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated	https://github.com/geneontology/go-ontology/issues/21133			This term was obsoleted because it represented an unnecessary grouping class.					True		EC:1.14.21.-		molecular_function											owl:Class	
GO:1905352	biolink:NamedThing	ciliary necklace assembly	The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace.	got7fsn_ti	cilial necklace assembly|cilium necklace assembly|cilial necklace formation|ciliary necklace formation|cilium necklace formation						pr	2016-08-05T14:01:23Z						biological_process											owl:Class	
GO:2000500	biolink:NamedThing	obsolete positive regulation of induction of apoptosis in response to chemical stimulus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of induction of apoptosis in response to chemical stimulus.	got7fsn_ti	positive regulation of induction of apoptosis in response to chemical stimulus|positive regulation of induction of apoptosis in response to chemical substance				This term was made obsolete because it is ill-defined.		yaf	2011-03-18T02:36:22Z		True				biological_process											owl:Class	
GO:1904679	biolink:NamedThing	myo-inositol import across plasma membrane	The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	myo-inositol import into cell						al	2012-07-03T06:22:05Z			GO:0097357			biological_process											owl:Class	
GO:0015484	biolink:NamedThing	obsolete hemolysin activity	OBSOLETE. Any substance that causes the lysis of red blood cells.	got7fsn_ti	hemolysin activity				This term was made obsolete because it represents a gene product.	GO:0019836				True				molecular_function											owl:Class	
GO:0038053	biolink:NamedThing	obsolete transcription factor activity, estrogen-activated RNA polymerase II transcription factor binding	OBSOLETE. Combining with estrogen and transmitting the signal to the transcriptional machinery by binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements.	got7fsn_ti	estrogen-activated RNA polymerase II transcription factor binding transcription factor activity|estrogen nuclear receptor activity				This term was obsoleted because it represents a GO-CAM model.		bf	2011-11-29T02:42:22Z		True				molecular_function											owl:Class	
GO:0048030	biolink:NamedThing	disaccharide binding	Binding to a disaccharide. Disaccharides are sugars composed of two monosaccharide units.	got7fsn_ti														molecular_function											owl:Class	
GO:0016128	biolink:NamedThing	phytosteroid metabolic process	The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.	got7fsn_ti	phytosteroid metabolism													biological_process											owl:Class	
GO:0120079	biolink:NamedThing	obsolete regulation of microfilament motor activity	OBSOLETE. Any process that modulates the frequency, rate or extent of microfilament motor activity.	got7fsn_ti	regulation of muscle motor activity|regulation of actin-filament motor activity|regulation of myosin ATPase activity|regulation of actin-activated ATPase activity|regulation of actin-dependent ATPase activity|regulation of actin filament motor activity	https://github.com/geneontology/go-ontology/issues/20877			This term was obsoleted because it represents a molecular function.	GO:0140659	krc	2017-07-05T20:53:49Z		True	GO:1904621			biological_process											owl:Class	
GO:0019631	biolink:NamedThing	quinate catabolic process	The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.	got7fsn_ti	quinate catabolism|quinate breakdown|quinic acid catabolism|quinic acid catabolic process|quinate degradation											MetaCyc:QUINATEDEG-PWY		biological_process											owl:Class	
GO:0006204	biolink:NamedThing	IMP catabolic process	The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate.	got7fsn_ti	IMP catabolism|IMP degradation|IMP breakdown													biological_process											owl:Class	
GO:0052117	biolink:NamedThing	obsolete aerotaxis in host environment	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	aerotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0071901	biolink:NamedThing	negative regulation of protein serine/threonine kinase activity	Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity.	got7fsn_ti							mah	2010-09-15T03:09:43Z						biological_process											owl:Class	
GO:0140615	biolink:NamedThing	ATP-dependent citrate lyase complex	A protein complex that catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA.	got7fsn_ti	citrate synthase complex|citrate lyase complex	https://github.com/geneontology/go-ontology/issues/21028					pg	2021-03-08T14:15:18Z						cellular_component											owl:Class	
CHEBI:64551	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016764	biolink:NamedThing	obsolete transferase activity, transferring other glycosyl groups	OBSOLETE. Catalysis of the transfer of a glycosyl group, other than hexosyl or pentosyl, from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring other glycosyl groups				This term was made obsolete because it was an unnecessary grouping term.	GO:0016757				True				molecular_function											owl:Class	
GO:0045897	biolink:NamedThing	obsolete positive regulation of transcription during mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.	got7fsn_ti	up regulation of transcription during mitosis|upregulation of transcription during mitosis|mitotic activation of transcription|up-regulation of transcription during mitosis|activation of transcription during mitosis|stimulation of transcription during mitosis|positive regulation of transcription, mitotic	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0045944				True				biological_process											owl:Class	
GO:0003813	biolink:NamedThing	obsolete classical-complement-pathway C3/C5 convertase activity	OBSOLETE. Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b.	got7fsn_ti	C5 convertase activity|C3 convertase activity|C42|classical-complement-pathway C3/C5 convertase activity|C4b,2a|complement C42|C423|C4b,2a,3b|complement C3 convertase activity|complement C2 activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1903192	biolink:NamedThing	sesquarterpene metabolic process	The chemical reactions and pathways involving sesquarterpene.	got7fsn_ti	sesquarterpene metabolism						tt	2014-07-16T17:04:47Z						biological_process											owl:Class	
GO:1902915	biolink:NamedThing	negative regulation of protein polyubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination.	got7fsn_ti	negative regulation of polyubiquitin|downregulation of protein polyubiquitination|downregulation of protein polyubiquitylation|down regulation of protein polyubiquitination|down-regulation of protein polyubiquitination|downregulation of polyubiquitin|inhibition of protein polyubiquitylation|down regulation of polyubiquitin|negative regulation of protein polyubiquitylation|down-regulation of polyubiquitin|negative regulation of protein polyubiquitinylation|down regulation of protein polyubiquitylation|inhibition of protein polyubiquitinylation|inhibition of protein polyubiquitination|down-regulation of protein polyubiquitylation|down regulation of protein polyubiquitinylation|inhibition of polyubiquitin|downregulation of protein polyubiquitinylation|down-regulation of protein polyubiquitinylation						di	2014-04-18T22:09:58Z						biological_process											owl:Class	
GO:1900663	biolink:NamedThing	positive regulation of emericellamide A biosynthetic process	Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process.	got7fsn_ti	up regulation of emericellamide A biosynthetic process|upregulation of emericellamide A synthesis|positive regulation of emericellamide A biosynthesis|up regulation of emericellamide A formation|positive regulation of emericellamide A synthesis|upregulation of emericellamide A formation|up regulation of emericellamide A anabolism|upregulation of emericellamide A anabolism|up-regulation of emericellamide A formation|activation of emericellamide A biosynthesis|upregulation of emericellamide A biosynthesis|activation of emericellamide A formation|up-regulation of emericellamide A biosynthetic process|up regulation of emericellamide A biosynthesis|up-regulation of emericellamide A synthesis|activation of emericellamide A anabolism|activation of emericellamide A synthesis|up regulation of emericellamide A synthesis|positive regulation of emericellamide A anabolism|positive regulation of emericellamide A formation|up-regulation of emericellamide A biosynthesis|activation of emericellamide A biosynthetic process|upregulation of emericellamide A biosynthetic process|up-regulation of emericellamide A anabolism						di	2012-05-22T04:13:36Z						biological_process											owl:Class	
GO:1905343	biolink:NamedThing	regulation of cohesin unloading	Any process that modulates the frequency, rate or extent of cohesin unloading.	got7fsn_ti							vw	2016-07-29T10:17:50Z						biological_process											owl:Class	
GO:1903518	biolink:NamedThing	positive regulation of single strand break repair	Any process that activates or increases the frequency, rate or extent of single strand break repair.	got7fsn_ti	up-regulation of single strand break repair|upregulation of single strand break repair|activation of single strand break repair|up regulation of single strand break repair						rl	2014-10-06T10:59:10Z						biological_process											owl:Class	
GO:1901993	biolink:NamedThing	regulation of meiotic cell cycle phase transition	Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition.	got7fsn_ti	meiotic cell cycle control|regulation of cell cycle transition						jl	2013-03-19T16:14:58Z						biological_process											owl:Class	
GO:1901356	biolink:NamedThing	beta-D-galactofuranose metabolic process	The chemical reactions and pathways involving beta-D-galactofuranose.	got7fsn_ti	beta-D-galactofuranose metabolism						di	2012-09-13T22:18:20Z						biological_process											owl:Class	
GO:0015480	biolink:NamedThing	obsolete secretin (sensu Bacteria)	OBSOLETE. Secretins are Gram-negative bacterial outer membrane proteins that form multimeric pores through which macromolecules, usually proteins, can pass. Form homomultimeric ring structures, 10-20 subunits per complex, with large central pores (inner diameters of 5-10 nm).	got7fsn_ti	secretin (sensu Bacteria)				This term was made obsolete because it represents a class of gene products.	GO:0045203|GO:0008320				True				molecular_function											owl:Class	
GO:1902189	biolink:NamedThing	2-methylbutanoyl-CoA(4-) metabolic process	The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-).	got7fsn_ti	2-methylbutanoyl-CoA(4-) metabolism						ms	2013-06-06T09:40:14Z						biological_process											owl:Class	
GO:1905717	biolink:NamedThing	positive regulation of cornification	Any process that activates or increases the frequency, rate or extent of cornification.	got7fsn_ti	activation of cornification|up-regulation of cornification|upregulation of cornification|up regulation of cornification						pga	2016-11-24T13:53:21Z						biological_process											owl:Class	
GO:1900233	biolink:NamedThing	positive regulation of single-species biofilm formation on inanimate substrate	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate.	got7fsn_ti	activation of single-species biofilm formation on inanimate substrate|up-regulation of single-species biofilm formation on inanimate substrate|up regulation of single-species biofilm formation on inanimate substrate|upregulation of single-species biofilm formation on inanimate substrate						di	2012-03-23T04:40:53Z						biological_process											owl:Class	
GO:1902958	biolink:NamedThing	positive regulation of mitochondrial electron transport, NADH to ubiquinone	Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.	got7fsn_ti	up-regulation of mitochondrial electron transport, NADH to ubiquinone|up regulation of mitochondrial electron transport, NADH to ubiquinone|up regulation of oxidative phosphorylation, NADH to ubiquinone|positive regulation of complex I (NADH to ubiquinone)|positive regulation of oxidative phosphorylation, NADH to ubiquinone|upregulation of oxidative phosphorylation, NADH to ubiquinone|activation of oxidative phosphorylation, NADH to ubiquinone|up-regulation of oxidative phosphorylation, NADH to ubiquinone|upregulation of mitochondrial electron transport, NADH to ubiquinone|activation of mitochondrial electron transport, NADH to ubiquinone|up regulation of complex I (NADH to ubiquinone)|upregulation of complex I (NADH to ubiquinone)|up-regulation of complex I (NADH to ubiquinone)|activation of complex I (NADH to ubiquinone)						dph	2014-05-02T15:30:24Z						biological_process											owl:Class	
GO:0006786	biolink:NamedThing	heme C biosynthetic process	The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f.	got7fsn_ti	haem C biosynthesis|heme C biosynthesis|heme C synthesis|haem C biosynthetic process|heme C anabolism|heme C formation													biological_process											owl:Class	
GO:1904597	biolink:NamedThing	negative regulation of connective tissue replacement involved in inflammatory response wound healing	Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.	got7fsn_ti	negative regulation of fibrosis during inflammatory response|inhibition of fibrosis during inflammatory response|downregulation of connective tissue replacement involved in inflammatory response wound healing|negative regulation of connective tissue replacement during inflammatory response|down-regulation of fibrosis during inflammatory response|downregulation of connective tissue replacement during inflammatory response|inhibition of connective tissue replacement involved in inflammatory response wound healing|down regulation of fibrosis during inflammatory response|down regulation of connective tissue replacement involved in inflammatory response wound healing|down-regulation of connective tissue replacement involved in inflammatory response wound healing|down-regulation of connective tissue replacement during inflammatory response|inhibition of connective tissue replacement during inflammatory response|downregulation of fibrosis during inflammatory response|down regulation of connective tissue replacement during inflammatory response						krc	2015-08-25T20:52:30Z						biological_process											owl:Class	
GO:0018911	biolink:NamedThing	1,2,4-trichlorobenzene metabolic process	The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.	got7fsn_ti	1,2,4-trichlorobenzene metabolism											UM-BBD_pathwayID:tbz		biological_process											owl:Class	
GO:0005986	biolink:NamedThing	sucrose biosynthetic process	The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside.	got7fsn_ti	sucrose biosynthesis|sucrose formation|sucrose synthesis|sucrose anabolism											MetaCyc:SUCSYN-PWY		biological_process											owl:Class	
GO:1900056	biolink:NamedThing	negative regulation of leaf senescence	Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence.	got7fsn_ti	inhibition of leaf senescence|down-regulation of leaf senescence|down regulation of leaf senescence|downregulation of leaf senescence						tb	2012-01-24T11:51:32Z						biological_process											owl:Class	
GO:0046082	biolink:NamedThing	5-methylcytosine biosynthetic process	The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA.	got7fsn_ti	5-methylcytosine formation|5-methylcytosine synthesis|5-methylcytosine biosynthesis|5-methylcytosine anabolism													biological_process											owl:Class	
GO:0010885	biolink:NamedThing	regulation of cholesterol storage	Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti														biological_process											owl:Class	
GO:0051482	biolink:NamedThing	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G protein-coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol.	got7fsn_ti	elevation of cytoplasmic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytoplasmic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|elevation of calcium ion concentration in cytoplasm during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of calcium ion concentration in cytosol during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytosolic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway													biological_process											owl:Class	
GO:1902986	biolink:NamedThing	regulation of lysine biosynthetic process via aminoadipic acid	Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.	got7fsn_ti	regulation of lysine biosynthetic process, aminoadipic pathway|regulation of lysine biosynthesis, aminoadipic pathway|regulation of lysine formation via aminoadipic acid|regulation of lysine anabolism via aminoadipic acid|regulation of lysine synthesis via aminoadipic acid|regulation of lysine biosynthetic process, aminoadipic acid pathway|regulation of lysine biosynthesis, aminoadipic acid pathway						al	2014-05-07T08:07:08Z						biological_process											owl:Class	
GO:1902948	biolink:NamedThing	negative regulation of tau-protein kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity.	got7fsn_ti	down-regulation of GSK|inhibition of tau protein kinase activity|negative regulation of tau protein kinase activity|inhibition of tau kinase activity|negative regulation of cdk5/p20|negative regulation of protein tau kinase activity|down regulation of TPK I|negative regulation of TPK II|negative regulation of tau-protein kinase II activity|down regulation of glycogen synthase kinase-3beta activity|down-regulation of glycogen synthase kinase-3beta activity|down regulation of tau-protein kinase II activity|downregulation of cdk5/p20|down-regulation of tau-protein kinase II activity|down-regulation of TPK|negative regulation of GSK|inhibition of tau-tubulin kinase activity|downregulation of TPK|negative regulation of tau kinase activity|negative regulation of STK31|down-regulation of TPK I|inhibition of brain protein kinase PK40erk activity|down-regulation of TPK II|inhibition of protein tau kinase activity|downregulation of tau protein kinase activity|downregulation of protein tau kinase activity|down regulation of protein tau kinase activity|inhibition of TPK|downregulation of glycogen synthase kinase-3beta activity|downregulation of tau-tubulin kinase activity|downregulation of TPK II|negative regulation of tau-tubulin kinase activity|down regulation of tau kinase activity|negative regulation of TPK|downregulation of TPK I|inhibition of GSK|down regulation of TTK|negative regulation of CDK5/p23|downregulation of [Tau protein] kinase activity|down regulation of tau-protein kinase activity|down-regulation of tau-protein kinase I activity|down regulation of CDK5/p23|down-regulation of STK31|negative regulation of glycogen synthase kinase-3beta activity|inhibition of tau-protein kinase II activity|inhibition of glycogen synthase kinase-3beta activity|down regulation of [Tau protein] kinase activity|down-regulation of cdk5/p20|down-regulation of TTK|downregulation of GSK|down regulation of cdk5/p20|downregulation of STK31|negative regulation of TPK I|down regulation of GSK|inhibition of cdk5/p20|down-regulation of brain protein kinase PK40erk activity|negative regulation of TTK|inhibition of tau-protein kinase activity|down regulation of STK31|inhibition of CDK5/p23|inhibition of STK31|down-regulation of tau-tubulin kinase activity|down-regulation of tau kinase activity|downregulation of brain protein kinase PK40erk activity|down-regulation of tau-protein kinase activity|down regulation of TPK II|down-regulation of tau protein kinase activity|inhibition of tau-protein kinase I activity|downregulation of tau-protein kinase II activity|down regulation of TPK|negative regulation of tau-protein kinase I activity|inhibition of TTK|down regulation of tau-protein kinase I activity|inhibition of TPK I|down-regulation of protein tau kinase activity|down-regulation of [Tau protein] kinase activity|negative regulation of brain protein kinase PK40erk activity|inhibition of [Tau protein] kinase activity|negative regulation of [Tau protein] kinase activity|down regulation of tau protein kinase activity|downregulation of CDK5/p23|downregulation of tau-protein kinase activity|down regulation of tau-tubulin kinase activity|down-regulation of CDK5/p23|downregulation of tau kinase activity|inhibition of TPK II|down regulation of brain protein kinase PK40erk activity|downregulation of TTK|downregulation of tau-protein kinase I activity						sjp	2014-05-02T08:43:32Z						biological_process											owl:Class	
GO:0090169	biolink:NamedThing	regulation of spindle assembly	Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.	got7fsn_ti	regulation of spindle formation						tb	2009-12-11T10:17:51Z						biological_process											owl:Class	
GO:1905459	biolink:NamedThing	regulation of vascular associated smooth muscle cell apoptotic process	Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.	got7fsn_ti	regulation of vascular smooth muscle cell apoptosis|regulation of vascular associated smooth muscle cell apoptosis|regulation of VSMC apoptotic process|regulation of VSMC apoptosis|regulation of vascular smooth muscle cell apoptotic process						rph	2016-09-19T11:33:54Z						biological_process											owl:Class	
GO:1904371	biolink:NamedThing	negative regulation of protein localization to actin cortical patch	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch.	got7fsn_ti	inhibition of protein localisation to actin cortical patch|down regulation of protein localization to actin cortical patch|downregulation of protein localisation to actin cortical patch|down-regulation of protein localisation to actin cortical patch|downregulation of protein localization to actin cortical patch|inhibition of protein localization to actin cortical patch|down regulation of protein localisation to actin cortical patch|negative regulation of protein localisation to actin cortical patch|down-regulation of protein localization to actin cortical patch						sl	2015-06-18T22:23:37Z						biological_process											owl:Class	
GO:1902560	biolink:NamedThing	GMP reductase complex	An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H(+) + NADPH => IMP + NADP(+) + NH(4)(+).	got7fsn_ti	GMP reductase|GMPR1 complex|GMPR2 complex|guanosine monophosphate reductase				An example of this is GMPR2 in human (UniProt Symbol Q9P2T1) in PMID:12009299 (inferred from direct assay).		bhm	2013-12-10T11:54:30Z						cellular_component											owl:Class	
GO:1904986	biolink:NamedThing	positive regulation of quinolinate biosynthetic process	Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process.	got7fsn_ti	positive regulation of quinolinate anabolism|activation of quinolinate formation|activation of quinolinate biosynthetic process|up regulation of quinolinate biosynthetic process|activation of quinolinate synthesis|up-regulation of quinolinate biosynthetic process|up regulation of quinolinate formation|up-regulation of quinolinate anabolism|activation of quinolinate biosynthesis|up-regulation of quinolinate formation|positive regulation of quinolinate synthesis|upregulation of quinolinate synthesis|activation of quinolinate anabolism|positive regulation of quinolinate formation|up-regulation of quinolinate synthesis|up regulation of quinolinate biosynthesis|upregulation of quinolinate formation|upregulation of quinolinate biosynthetic process|up-regulation of quinolinate biosynthesis|up regulation of quinolinate anabolism|upregulation of quinolinate biosynthesis|upregulation of quinolinate anabolism|up regulation of quinolinate synthesis|positive regulation of quinolinate biosynthesis						bf	2016-02-29T15:54:29Z						biological_process											owl:Class	
GO:0034671	biolink:NamedThing	retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros.	got7fsn_ti	retinoic acid receptor signalling pathway involved in pronephros anterior-posterior patterning|retinoic acid receptor signaling pathway involved in pronephric kidney anterior/posterior pattern specification													biological_process											owl:Class	
UBERON:0009571	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0017164	biolink:NamedThing	obsolete nicotinic acetylcholine receptor-associated protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nicotinic acetylcholine receptor-associated protein activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005102|GO:0005515				True				molecular_function											owl:Class	
GO:0039572	biolink:NamedThing	obsolete suppression by virus of host STAT2 activity by negative regulation of STAT2 tyrosine phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT2 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT2, thereby preventing STAT2 activation.	got7fsn_ti	inhibition by virus of tyrosine phosphorylation of STAT2				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:53:50Z		True				biological_process											owl:Class	
GO:0052194	biolink:NamedThing	obsolete movement on or near symbiont	OBSOLETE. The directed movement of an organism or motile cell on or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti										True				biological_process											owl:Class	
GO:0039549	biolink:NamedThing	obsolete suppression by virus of host IRF3 activity by inhibition of IRF3 phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of the phosphorylation of IRF3 (interferon regulatory factor-3), thereby inhibiting IRF3 activation. In response to signaling from RIG-1/MDA-5 receptors, IRF3 is phosphorylated on multiple serine and threonine residues; phosphorylation results in the cytoplasm-to-nucleus translocation of IRF3, DNA binding, and increased transcriptional activation of interferon-encoding genes.	got7fsn_ti	inhibition of virus-induced IRF-3 phosphorylation|inhibition of phosphorylation-induced activation of host IRF3				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-19T04:27:06Z		True				biological_process											owl:Class	
GO:1905408	biolink:NamedThing	negative regulation of creatine transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity.	got7fsn_ti	down-regulation of creatine transmembrane transporter activity|inhibition of creatine transmembrane transporter activity|downregulation of creatine transmembrane transporter activity|down regulation of creatine transmembrane transporter activity						bc	2016-08-25T15:08:56Z						biological_process											owl:Class	
GO:0019548	biolink:NamedThing	arginine catabolic process to spermine	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine.	got7fsn_ti	arginine degradation to spermine|arginine breakdown to spermine											MetaCyc:ARGSPECAT-PWY		biological_process											owl:Class	
GO:0044367	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060589	biolink:NamedThing	nucleoside-triphosphatase regulator activity	Binds to and modulates the activity of an NTPase.	got7fsn_ti	NTPase regulator activity						dph	2009-05-08T02:49:24Z						molecular_function											owl:Class	
GO:2001161	biolink:NamedThing	negative regulation of histone H3-K79 methylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 methylation.	got7fsn_ti	negative regulation of histone H3 K79 methylation|negative regulation of histone lysine H3 K79 methylation|negative regulation of histone H3K79me						se	2011-10-25T10:27:05Z						biological_process											owl:Class	
GO:0031281	biolink:NamedThing	positive regulation of cyclase activity	Any process that activates or increases the activity of a cyclase.	got7fsn_ti	stimulation of cyclase activity|up regulation of cyclase activity|up-regulation of cyclase activity|activation of cyclase activity|upregulation of cyclase activity													biological_process											owl:Class	
GO:1905262	biolink:NamedThing	negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.	got7fsn_ti	inhibition of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|down-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|down regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|downregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination						se	2016-06-13T20:45:10Z						biological_process											owl:Class	
GO:0044150	biolink:NamedThing	obsolete development of host on or near symbiont surface	OBSOLETE. The progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	development of organism on or near symbiont surface				The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-06T03:15:52Z		True				biological_process											owl:Class	
GO:2001038	biolink:NamedThing	regulation of cellular response to drug	Any process that modulates the frequency, rate or extent of cellular response to drug.	got7fsn_ti							yaf	2011-08-27T04:12:19Z						biological_process											owl:Class	
GO:0046876	biolink:NamedThing	3,4-didehydroretinal binding	Binding to 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod).	got7fsn_ti	red-sensitive opsin|violet-sensitive opsin|blue-sensitive opsin|opsin|long-wave-sensitive opsin|short-wave-sensitive opsin|UV-sensitive opsin|green-sensitive opsin													molecular_function											owl:Class	
GO:0032382	biolink:NamedThing	positive regulation of intracellular sterol transport	Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.	got7fsn_ti	up-regulation of intracellular sterol transport|up regulation of intracellular sterol transport|stimulation of intracellular sterol transport|activation of intracellular sterol transport|upregulation of intracellular sterol transport													biological_process											owl:Class	
GO:1903398	biolink:NamedThing	regulation of m7G(5')pppN diphosphatase activity	Any process that modulates the frequency, rate or extent of m7G(5')pppN diphosphatase activity.	got7fsn_ti	regulation of m7G(5')pppN pyrophosphatase activity|regulation of M(7)G(5')pppN pyrophosphatase activity|regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|regulation of decapase activity						mah	2014-09-01T10:16:40Z						biological_process											owl:Class	
GO:0032112	biolink:NamedThing	negative regulation of protein histidine kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity.	got7fsn_ti	downregulation of protein histidine kinase activity|down regulation of protein histidine kinase activity|inhibition of protein histidine kinase activity|protein histidine kinase inhibitor|down-regulation of protein histidine kinase activity													biological_process											owl:Class	
GO:1903971	biolink:NamedThing	positive regulation of response to macrophage colony-stimulating factor	Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor.	got7fsn_ti	upregulation of response to macrophage colony-stimulating factor stimulus|up-regulation of response to M-CSF|up-regulation of response to macrophage colony-stimulating factor|activation of response to M-CSF|positive regulation of response to macrophage colony-stimulating factor|up-regulation of response to macrophage colony-stimulating factor stimulus|upregulation of response to macrophage colony-stimulating factor|positive regulation of response to M-CSF|activation of response to macrophage colony-stimulating factor stimulus|positive regulation of response to macrophage colony-stimulating factor stimulus|up regulation of response to M-CSF|upregulation of response to M-CSF|up regulation of response to macrophage colony-stimulating factor|up regulation of response to macrophage colony-stimulating factor stimulus|activation of response to macrophage colony-stimulating factor						nc	2015-03-02T14:41:14Z						biological_process											owl:Class	
GO:2001096	biolink:NamedThing	cellotriose transport	The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:06:27Z						biological_process											owl:Class	
GO:0008551	biolink:NamedThing	P-type cadmium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out).	got7fsn_ti	Cd2+-exporting ATPase activity|cadmium exporting ATPase activity|cadmium-exporting ATPase activity|cadmium transmembrane transporter activity, phosphorylative mechanism|cadmium-translocating P-type ATPase activity|Cd(2+)-exporting ATPase activity										GO:0008561	EC:7.2.2.21|RHEA:12132|MetaCyc:3.6.3.3-RXN		molecular_function											owl:Class	
GO:1901346	biolink:NamedThing	negative regulation of vasculature development involved in avascular cornea development in camera-type eye	Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye.	got7fsn_ti	down-regulation of vascular system development involved in avascular cornea development in camera-type eye|down-regulation of vasculature development involved in avascular cornea development in camera-type eye|downregulation of vascular system development involved in avascular cornea development|downregulation of vasculature development involved in avascular cornea development in camera-type eye|downregulation of vascular system development involved in avascular cornea development in camera-type eye|down regulation of vascular system development involved in avascular cornea development|down regulation of vasculature development involved in avascular cornea development in camera-type eye|inhibition of vasculature development involved in avascular cornea development|downregulation of vasculature development involved in avascular cornea development|negative regulation of vascular system development involved in avascular cornea development in camera-type eye|inhibition of vascular system development involved in avascular cornea development in camera-type eye|inhibition of vascular system development involved in avascular cornea development|down regulation of vascular system development involved in avascular cornea development in camera-type eye|inhibition of vasculature development involved in avascular cornea development in camera-type eye|down regulation of vasculature development involved in avascular cornea development|down-regulation of vasculature development involved in avascular cornea development|negative regulation of vascular system development involved in avascular cornea development|down-regulation of vascular system development involved in avascular cornea development|negative regulation of vasculature development involved in avascular cornea development						bf	2012-09-07T15:53:40Z						biological_process											owl:Class	
GO:0023062	biolink:NamedThing	obsolete signal transmission via transcytosis	OBSOLETE. The process in which a signal is conveyed via transcytosis. Transcytosis is the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.	got7fsn_ti	signal transmission via transcytosis				This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052|GO:0045056		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0009179	biolink:NamedThing	purine ribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine ribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0010651	biolink:NamedThing	negative regulation of cell communication by electrical coupling	Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti														biological_process											owl:Class	
GO:0120076	biolink:NamedThing	negative regulation of endocardial cushion cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation.	got7fsn_ti							krc	2017-06-26T23:37:23Z						biological_process											owl:Class	
GO:2000641	biolink:NamedThing	regulation of early endosome to late endosome transport	Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.	got7fsn_ti							vk	2011-04-21T11:20:02Z						biological_process											owl:Class	
GO:0005189	biolink:NamedThing	obsolete milk protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	milk protein				This term was made obsolete because it describes presence in body fluids rather than an activity.					True				molecular_function											owl:Class	
GO:1905629	biolink:NamedThing	positive regulation of serotonin biosynthetic process	Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process.	got7fsn_ti	activation of serotonin anabolism|up regulation of serotonin biosynthetic process|up regulation of serotonin biosynthesis|upregulation of serotonin synthesis|up-regulation of serotonin formation|positive regulation of serotonin synthesis|upregulation of serotonin anabolism|positive regulation of serotonin anabolism|up-regulation of serotonin biosynthetic process|activation of serotonin biosynthesis|upregulation of serotonin biosynthetic process|positive regulation of serotonin formation|activation of serotonin formation|upregulation of serotonin biosynthesis|up-regulation of serotonin anabolism|up regulation of serotonin anabolism|up regulation of serotonin synthesis|up regulation of serotonin formation|up-regulation of serotonin biosynthesis|activation of serotonin synthesis|positive regulation of serotonin biosynthesis|activation of serotonin biosynthetic process|upregulation of serotonin formation|up-regulation of serotonin synthesis						pad	2016-10-31T14:26:36Z						biological_process											owl:Class	
GO:0060903	biolink:NamedThing	positive regulation of meiosis I	Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.	got7fsn_ti							dph	2009-08-14T01:06:57Z						biological_process											owl:Class	
GO:2000960	biolink:NamedThing	regulation of cellooligosaccharide metabolic process	Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process.	got7fsn_ti	regulation of cellooligosaccharide metabolism						tt	2011-08-01T02:25:54Z						biological_process											owl:Class	
GO:1904957	biolink:NamedThing	negative regulation of midbrain dopaminergic neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation.	got7fsn_ti	down regulation of mDA neuron differentiation|downregulation of midbrain dopaminergic neuron production|downregulation of DA neurogenesis from midbrain floor plate|downregulation of midbrain DA neurogenesis|downregulation of midbrain dopaminergic neuron differentiation|down regulation of midbrain dopaminergic neuron production|inhibition of mDA neuron differentiation|negative regulation of midbrain DA neurogenesis|down-regulation of midbrain dopaminergic neuron production|downregulation of mDA neuron differentiation|inhibition of midbrain dopaminergic neuron differentiation|negative regulation of DA neurogenesis from midbrain floor plate|down regulation of midbrain DA neurogenesis|down regulation of midbrain dopaminergic neuron differentiation|inhibition of midbrain DA neurogenesis|down-regulation of mDA neuron differentiation|negative regulation of midbrain dopaminergic neuron production|down-regulation of midbrain DA neurogenesis|inhibition of midbrain dopaminergic neuron production|negative regulation of mDA neuron differentiation|inhibition of DA neurogenesis from midbrain floor plate|down-regulation of DA neurogenesis from midbrain floor plate|down-regulation of midbrain dopaminergic neuron differentiation|down regulation of DA neurogenesis from midbrain floor plate						bf	2016-02-09T12:00:29Z						biological_process											owl:Class	
GO:1903272	biolink:NamedThing	positive regulation of cytoplasmic translational elongation through polyproline stretches	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.	got7fsn_ti	upregulation of cytoplasmic translational elongation through polyproline stretches|up regulation of cytoplasmic translational elongation through polyproline stretches|up-regulation of cytoplasmic translational elongation through polyproline stretches|activation of cytoplasmic translational elongation through polyproline stretches						mcc	2014-08-08T14:54:16Z						biological_process											owl:Class	
GO:0075206	biolink:NamedThing	obsolete positive regulation by host of symbiont cAMP-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by host of symbiont cAMP-mediated signaling				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:1905713	biolink:NamedThing	obsolete mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium ion concentration	OBSOLETE. Any mitochondrial calcium uptake that is involved in regulation of presynaptic cytosolic calcium ion concentration.	got7fsn_ti	calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration|mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium levels				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2016-11-23T15:55:53Z		True				biological_process											owl:Class	
GO:0043302	biolink:NamedThing	positive regulation of leukocyte degranulation	Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.	got7fsn_ti	up regulation of leukocyte degranulation|positive regulation of leucocyte degranulation|upregulation of leukocyte degranulation|up-regulation of leukocyte degranulation|positive regulation of immune cell degranulation|activation of leukocyte degranulation|stimulation of leukocyte degranulation													biological_process											owl:Class	
GO:1902880	biolink:NamedThing	obsolete positive regulation of BMP signaling pathway involved in spinal cord association neuron specification	OBSOLETE. Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.	got7fsn_ti	up regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|activation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|activation of BMP signaling pathway involved in spinal cord association neuron specification|upregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|positive regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|activation of BMP signalling pathway involved in spinal cord association neuron specification|up regulation of BMP signaling pathway involved in spinal cord association neuron specification|activation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|up regulation of BMP signalling pathway involved in spinal cord association neuron specification|up regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|positive regulation of BMP signalling pathway involved in spinal cord association neuron specification|upregulation of BMP signalling pathway involved in spinal cord association neuron specification|upregulation of BMP signaling pathway involved in spinal cord association neuron specification|upregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|up-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up-regulation of BMP signalling pathway involved in spinal cord association neuron specification|positive regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up-regulation of BMP signaling pathway involved in spinal cord association neuron specification				The reason for obsoletion is that this term represents a GO-CAM model.		mr	2014-04-03T15:25:43Z		True				biological_process											owl:Class	
UBERON:0002421	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901052	biolink:NamedThing	sarcosine metabolic process	The chemical reactions and pathways involving sarcosine.	got7fsn_ti	sarcosine metabolism						yaf	2012-06-28T04:52:04Z						biological_process											owl:Class	
GO:0016484	biolink:NamedThing	obsolete proprotein convertase 2 activator activity	OBSOLETE. Required for the maturation and activation of proprotein convertase 2.	got7fsn_ti	proprotein convertase 2 activator activity				This term was made obsolete because it represents a regulator of an obsolete molecular function.	GO:0016504				True				molecular_function											owl:Class	
GO:0036058	biolink:NamedThing	filtration diaphragm assembly	The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.	got7fsn_ti							bf	2011-12-12T04:38:40Z						biological_process											owl:Class	
GO:1905795	biolink:NamedThing	cellular response to puromycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.	got7fsn_ti	cellular response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine						sl	2017-01-10T21:13:28Z						biological_process											owl:Class	
GO:0046043	biolink:NamedThing	TDP metabolic process	The chemical reactions and pathways involving TDP, ribosylthymine diphosphate.	got7fsn_ti	TDP metabolism													biological_process											owl:Class	
GO:1902537	biolink:NamedThing	obsolete multi-organism pinocytosis	OBSOLETE. A pinocytosis which involves another organism.	got7fsn_ti					This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-02T14:14:46Z		True				biological_process											owl:Class	
GO:0000230	biolink:NamedThing	obsolete nuclear mitotic chromosome	OBSOLETE. A chromosome found in the nucleus during mitosis.	got7fsn_ti	nuclear mitotic chromosome				This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000794				True				cellular_component											owl:Class	
GO:0046385	biolink:NamedThing	deoxyribose phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.	got7fsn_ti	deoxyribose phosphate formation|deoxyribose phosphate anabolism|deoxyribose phosphate synthesis|deoxyribose phosphate biosynthesis													biological_process											owl:Class	
GO:1903126	biolink:NamedThing	negative regulation of centriole-centriole cohesion	Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion.	got7fsn_ti	downregulation of centriole-centriole cohesion|down regulation of centriole-centriole cohesion|inhibition of centriole-centriole cohesion|down-regulation of centriole-centriole cohesion						als	2014-06-24T09:31:45Z						biological_process											owl:Class	
GO:0015858	biolink:NamedThing	nucleoside transport	The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1902268	biolink:NamedThing	negative regulation of polyamine transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport.	got7fsn_ti	downregulation of polyamine transmembrane transport|down regulation of polyamine transmembrane transport|down-regulation of polyamine transmembrane transport|inhibition of polyamine transmembrane transport						mcc	2013-06-28T21:34:42Z						biological_process											owl:Class	
GO:1900525	biolink:NamedThing	obsolete positive regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-03T05:13:55Z		True				biological_process											owl:Class	
CHEBI:18385	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046226	biolink:NamedThing	coumarin catabolic process	The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.	got7fsn_ti	coumarin breakdown|coumarin degradation|coumarin catabolism													biological_process											owl:Class	
GO:1905593	biolink:NamedThing	positive regulation of optical nerve axon regeneration	Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration.	got7fsn_ti	activation of optical nerve axon regeneration|up regulation of optical nerve axon regeneration|upregulation of optical nerve axon regeneration|up-regulation of optical nerve axon regeneration						pga	2016-10-25T12:58:58Z						biological_process											owl:Class	
GO:0005803	biolink:NamedThing	obsolete secretory vesicle	OBSOLETE. A small subcellular vesicle, or granule, surrounded by a single-layered membrane; formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.	got7fsn_ti	transition vesicle|secretory vesicle				This term was made obsolete because it was being used to describe two different components.	GO:0030133|GO:0030141				True				cellular_component											owl:Class	
GO:0015642	biolink:NamedThing	obsolete bacteriolytic toxin activity	OBSOLETE. Acts as to cause lysis of bacterial cells.	got7fsn_ti	bacteriolytic toxin activity				This term was made obsolete because it represents a class of gene products and not a molecular function.	GO:0019835				True				molecular_function											owl:Class	
GO:1904567	biolink:NamedThing	response to wortmannin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.	got7fsn_ti	response to wartmannin						sl	2015-08-19T16:22:28Z						biological_process											owl:Class	
GO:1990086	biolink:NamedThing	lens fiber cell apoptotic process	Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.	got7fsn_ti							hjd	2013-05-01T19:09:28Z						biological_process											owl:Class	
GO:2000012	biolink:NamedThing	regulation of auxin polar transport	Any process that modulates the frequency, rate or extent of auxin polar transport.	got7fsn_ti							tb	2010-08-05T11:21:09Z						biological_process											owl:Class	
GO:0034164	biolink:NamedThing	negative regulation of toll-like receptor 9 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway.	got7fsn_ti	negative regulation of TLR9 signaling pathway|negative regulation of toll-like receptor 9 signalling pathway													biological_process											owl:Class	
GO:0006108	biolink:NamedThing	malate metabolic process	The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.	got7fsn_ti	malate metabolism													biological_process											owl:Class	
GO:1903763	biolink:NamedThing	gap junction channel activity involved in cell communication by electrical coupling	Any gap junction channel activity that is involved in cell communication by electrical coupling.	got7fsn_ti	innexin channel activity involved in cell communication by electrical coupling|connexin involved in cell communication by electrical coupling|innexin involved in cell communication by electrical coupling						rl	2014-12-19T15:43:16Z						molecular_function											owl:Class	
GO:0140280	biolink:NamedThing	negative regulation of mitotic division septum assembly	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	got7fsn_ti	down regulation of division septum formation involved in mitotic cell cycle|inhibition of septin assembly and septum biosynthesis involved in mitotic cell cycle|negative regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|down-regulation of septin assembly and septum formation involved in mitotic cell cycle|inhibition of division septum formation involved in mitotic cell cycle|negative regulation of septin assembly and septum formation involved in mitotic cell cycle|down-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|downregulation of formation of division septum involved in mitotic cell cycle|negative regulation of division septum formation involved in mitotic cell cycle|downregulation of division septum formation involved in mitotic cell cycle|down-regulation of division septum formation involved in mitotic cell cycle|inhibition of septin assembly and septum formation involved in mitotic cell cycle|inhibition of mitotic division septum assembly|down regulation of formation of division septum involved in mitotic cell cycle|down-regulation of mitotic division septum assembly|downregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|down regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|downregulation of mitotic division septum assembly|down regulation of septin assembly and septum formation involved in mitotic cell cycle|downregulation of septin assembly and septum formation involved in mitotic cell cycle|down regulation of mitotic division septum assembly|down-regulation of formation of division septum involved in mitotic cell cycle|inhibition of formation of division septum involved in mitotic cell cycle|negative regulation of formation of division septum involved in mitotic cell cycle						pg	2018-10-08T10:03:22Z						biological_process											owl:Class	
GO:1901745	biolink:NamedThing	prephenate(2-) metabolic process	The chemical reactions and pathways involving prephenate(2-).	got7fsn_ti	prephenate metabolism|prephenate(2-) metabolism						yaf	2013-01-14T10:13:49Z						biological_process											owl:Class	
GO:0120158	biolink:NamedThing	positive regulation of collagen catabolic process	Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.	got7fsn_ti	positive regulation of collagen degradation|positive regulation of collagen breakdown|up regulation of collagen catabolic process|positive regulation of collagen catabolism|activation of collagen catabolic process|up-regulation of collagen catabolic process|upregulation of collagen catabolic process						krc	2018-05-11T16:31:42Z						biological_process											owl:Class	
GO:1903855	biolink:NamedThing	positive regulation of stress response to copper ion	Any process that activates or increases the frequency, rate or extent of stress response to copper ion.	got7fsn_ti	upregulation of stress response to copper ion|positive regulation of response to copper toxicity|activation of stress response to copper ion|upregulation of response to copper ion stress|up regulation of response to copper toxicity|up regulation of stress response to copper ion|positive regulation of response to copper ion stress|activation of response to copper toxicity|up regulation of response to copper ion stress|up-regulation of response to copper toxicity|up-regulation of stress response to copper ion|upregulation of response to copper toxicity|up-regulation of response to copper ion stress|activation of response to copper ion stress						kmv	2015-01-29T20:15:42Z						biological_process											owl:Class	
GO:0036487	biolink:NamedThing	nitric-oxide synthase inhibitor activity	Binds to and stops, prevents or reduces the activity of nitric oxide synthase.	got7fsn_ti	NOS inhibitor activity|nitric oxide synthase inhibitor activity						bf	2014-09-09T15:07:20Z						molecular_function											owl:Class	
GO:0019339	biolink:NamedThing	parathion catabolic process	The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.	got7fsn_ti	parathion degradation|parathion breakdown|parathion catabolism											MetaCyc:PARATHION-DEGRADATION-PWY		biological_process											owl:Class	
GO:0047484	biolink:NamedThing	regulation of response to osmotic stress	Any process that modulates the rate or extent of the response to osmotic stress.	got7fsn_ti														biological_process											owl:Class	
GO:0051005	biolink:NamedThing	negative regulation of lipoprotein lipase activity	Any process that stops or reduces the activity of the enzyme lipoprotein lipase.	got7fsn_ti	downregulation of lipoprotein lipase activity|down-regulation of lipoprotein lipase activity|inhibition of lipoprotein lipase activity|down regulation of lipoprotein lipase activity													biological_process											owl:Class	
GO:0003393	biolink:NamedThing	neuron migration involved in retrograde extension	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension.	got7fsn_ti							dph	2009-12-09T09:36:03Z						biological_process											owl:Class	
GO:1903533	biolink:NamedThing	regulation of protein targeting	Any process that modulates the frequency, rate or extent of protein targeting.	got7fsn_ti	regulation of protein sorting along secretory pathway|regulation of nascent polypeptide association						al	2014-10-08T14:49:03Z						biological_process											owl:Class	
GO:1902821	biolink:NamedThing	1-undecene biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-undecene.	got7fsn_ti	1-undecene formation|1-undecene biosynthesis|1-undecene synthesis|1-undecene anabolism						tt	2014-03-31T02:51:19Z						biological_process											owl:Class	
GO:0098917	biolink:NamedThing	retrograde trans-synaptic signaling	Cell-cell signaling from post to pre-synapse, across the synaptic cleft.	got7fsn_ti														biological_process											owl:Class	
GO:0047477	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001166	biolink:NamedThing	regulation of histone H2B ubiquitination	Any process that modulates the frequency, rate or extent of histone H2B ubiquitination.	got7fsn_ti							se	2011-10-25T10:49:51Z						biological_process											owl:Class	
GO:1905003	biolink:NamedThing	picolinic acid metabolic process	The chemical reactions and pathways involving picolinic acid.	got7fsn_ti	picolinate metabolism|picolinic acid metabolism						bf	2016-03-01T14:06:28Z						biological_process											owl:Class	
GO:1905048	biolink:NamedThing	regulation of metallopeptidase activity	Any process that modulates the frequency, rate or extent of metallopeptidase activity.	got7fsn_ti	regulation of metalloproteinase activity|regulation of metalloprotease activity						mm2	2016-03-15T16:44:27Z						biological_process											owl:Class	
GO:1902273	biolink:NamedThing	negative regulation of (R)-carnitine transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport.	got7fsn_ti	downregulation of (R)-carnitine transmembrane transport|down regulation of (R)-carnitine transmembrane transport|down-regulation of (R)-carnitine transmembrane transport|inhibition of (R)-carnitine transmembrane transport						mcc	2013-07-01T13:13:17Z						biological_process											owl:Class	
GO:1901964	biolink:NamedThing	positive regulation of cell proliferation involved in outflow tract morphogenesis	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.	got7fsn_ti	upregulation of cell proliferation involved in outflow tract morphogenesis|up-regulation of cell proliferation involved in outflow tract morphogenesis|activation of cell proliferation involved in outflow tract morphogenesis|up regulation of cell proliferation involved in outflow tract morphogenesis						dph	2013-02-20T20:30:31Z						biological_process											owl:Class	
GO:0010481	biolink:NamedThing	epidermal cell division	Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.	got7fsn_ti	hypodermal cell division													biological_process											owl:Class	
GO:0002590	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide antigen via MHC class I	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.	got7fsn_ti	down-regulation of antigen processing and presentation of peptide antigen via MHC class I|negative regulation of peptide antigen processing and presentation via MHC class I|inhibition of antigen processing and presentation of peptide antigen via MHC class I|downregulation of antigen processing and presentation of peptide antigen via MHC class I|down regulation of antigen processing and presentation of peptide antigen via MHC class I													biological_process											owl:Class	
GO:0048299	biolink:NamedThing	regulation of isotype switching to IgD isotypes	Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.	got7fsn_ti	regulation of class switching to IgD isotypes|regulation of isotype switch recombination to IgD isotypes|regulation of class switch recombination to IgD isotypes													biological_process											owl:Class	
GO:1903603	biolink:NamedThing	thermospermine biosynthetic process	The chemical reactions and pathways resulting in the formation of thermospermine.	got7fsn_ti	thermospermine anabolism|thermospermine biosynthesis|thermospermine formation|thermospermine synthesis						tb	2014-11-12T18:48:12Z						biological_process											owl:Class	
GO:1902805	biolink:NamedThing	positive regulation of synaptic vesicle transport	Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport.	got7fsn_ti	up regulation of synaptic vesicle fusion|upregulation of synaptic vesicle fusion|up-regulation of synaptic vesicle transport|activation of synaptic vesicle transport|activation of synaptic vesicle fission|positive regulation of synaptic vesicle fission|upregulation of synaptic vesicle transport|positive regulation of synaptic vesicle fusion|up regulation of synaptic vesicle fission|up-regulation of synaptic vesicle fusion|up regulation of synaptic vesicle transport|upregulation of synaptic vesicle fission|activation of synaptic vesicle fusion|up-regulation of synaptic vesicle fission						kmv	2014-03-25T14:56:46Z						biological_process											owl:Class	
GO:0051350	biolink:NamedThing	negative regulation of lyase activity	Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.	got7fsn_ti	downregulation of lyase activity|down regulation of lyase activity|down-regulation of lyase activity|lyase inhibitor|inhibition of lyase activity													biological_process											owl:Class	
GO:0008243	biolink:NamedThing	obsolete plasminogen activator activity	OBSOLETE. Catalysis of the specific cleavage of an Arg-Val bond in plasminogen to form plasmin.	got7fsn_ti	u-plasminogen activator activity|plasminogen activator, tissue-type|plasminogen activator activity|two-chain urokinase-type plasminogen activator|uPA|u-PA|urinary plasminogen activator activity|tissue-type plasminogen activator activity|tissue plasminogen activator activity|double-chain urokinase-type plasminogen activator|t-plasminogen activator activity|t-PA|urokinase plasminogen activator|urokinase activity|cellular plasminogen activator activity|urokinase-type plasminogen activator|abbokinase activity|tPA activity|urinary esterase A			GO:0004252	This term was made obsolete because it represents a gene product.					True	GO:0004297|GO:0004296			molecular_function											owl:Class	
GO:0046001	biolink:NamedThing	negative regulation of preblastoderm mitotic cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle.	got7fsn_ti	negative regulation of preblastoderm mitotic cell cycle progression|downregulation of progression through preblastoderm mitotic cell cycle|negative regulation of progression through preblastoderm mitotic cell cycle|down regulation of progression through preblastoderm mitotic cell cycle|inhibition of progression through preblastoderm mitotic cell cycle|down-regulation of progression through preblastoderm mitotic cell cycle													biological_process											owl:Class	
GO:0052479	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|suppression by organism of defense-related symbiont ethylene-mediated signal transduction pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0042307	biolink:NamedThing	positive regulation of protein import into nucleus	Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.	got7fsn_ti	positive regulation of protein transport from cytoplasm to nucleus|activation of protein import into nucleus|positive regulation of protein import into cell nucleus|positive regulation of protein-nucleus import|stimulation of protein import into nucleus|upregulation of protein import into nucleus|up-regulation of protein import into nucleus|up regulation of protein import into nucleus													biological_process											owl:Class	
GO:0015391	biolink:NamedThing	nucleobase:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in).	got7fsn_ti														molecular_function											owl:Class	
GO:1903796	biolink:NamedThing	negative regulation of inorganic anion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport.	got7fsn_ti	negative regulation of inorganic anion membrane transport|negative regulation of transmembrane inorganic anion transport|downregulation of inorganic anion transmembrane transport|down regulation of inorganic anion membrane transport|down regulation of transmembrane inorganic anion transport|inhibition of inorganic anion membrane transport|down regulation of inorganic anion transmembrane transport|down-regulation of transmembrane inorganic anion transport|inhibition of inorganic anion transmembrane transport|inhibition of transmembrane inorganic anion transport|down-regulation of inorganic anion membrane transport|downregulation of transmembrane inorganic anion transport|downregulation of inorganic anion membrane transport|down-regulation of inorganic anion transmembrane transport						sl	2015-01-14T21:44:59Z						biological_process											owl:Class	
GO:0034136	biolink:NamedThing	negative regulation of toll-like receptor 2 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.	got7fsn_ti	negative regulation of TLR2 signaling pathway|negative regulation of toll-like receptor 2 signalling pathway													biological_process											owl:Class	
GO:0100039	biolink:NamedThing	obsolete regulation of pyrimidine nucleotide biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates pyrimidine nucleotide biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0034131	biolink:NamedThing	regulation of toll-like receptor 1 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 1 signalling pathway|regulation of TLR1 signaling pathway													biological_process											owl:Class	
GO:1990076	biolink:NamedThing	cell wall polysaccharide catabolic process involved in abscission	Any cell wall polysaccharide catabolic process that is involved in abscission.	got7fsn_ti							dhl	2013-04-25T16:29:43Z						biological_process											owl:Class	
GO:1904573	biolink:NamedThing	regulation of selenocysteine insertion sequence binding	Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding.	got7fsn_ti	regulation of SECIS binding						sl	2015-08-19T17:51:09Z						biological_process											owl:Class	
GO:1904766	biolink:NamedThing	negative regulation of macroautophagy by TORC1 signaling	A TORC1 signaling that results in negative regulation of macroautophagy.	got7fsn_ti	negative regulation of non-specific autophagy by TORC1 signaling|negative regulation of non-specific autophagy by TORC1 signal transduction|negative regulation of autophagy in response to cellular starvation by TORC1 signaling|negative regulation of starvation-induced autophagy by TORC1 signaling|negative regulation of starvation-induced autophagy by TORC1 signal transduction|negative regulation of macroautophagy by TORC1 signal transduction|negative regulation of autophagy in response to cellular starvation by TORC1 signal transduction						dph	2015-10-26T18:34:47Z						biological_process											owl:Class	
GO:0038013	biolink:NamedThing	positive regulation of Wnt signaling pathway by Wnt receptor internalization	Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway.	got7fsn_ti	positive regulation of Wnt receptor signaling pathway by Wnt receptor internalization|positive regulation of Wnt-activated signaling pathway by Wnt receptor internalization|positive regulation of Wnt receptor signaling pathway by Frizzled internalization|positive regulation of Wnt receptor signaling pathway by LRP6 internalization|positive regulation of Wnt receptor signalling pathway by Wnt receptor endocytosis						bf	2011-06-23T04:02:21Z						biological_process											owl:Class	
GO:1903181	biolink:NamedThing	positive regulation of dopamine biosynthetic process	Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process.	got7fsn_ti	up-regulation of dopamine biosynthetic process|activation of dopamine formation|upregulation of dopamine formation|positive regulation of dopamine formation|up-regulation of dopamine formation|activation of dopamine biosynthesis|up-regulation of dopamine anabolism|activation of dopamine synthesis|up regulation of dopamine biosynthetic process|upregulation of dopamine biosynthesis|up regulation of dopamine synthesis|positive regulation of dopamine anabolism|up-regulation of dopamine synthesis|activation of dopamine anabolism|upregulation of dopamine biosynthetic process|positive regulation of dopamine synthesis|upregulation of dopamine synthesis|up regulation of dopamine biosynthesis|up regulation of dopamine formation|up-regulation of dopamine biosynthesis|positive regulation of dopamine biosynthesis|activation of dopamine biosynthetic process|upregulation of dopamine anabolism|up regulation of dopamine anabolism						bf	2014-07-14T12:17:53Z						biological_process											owl:Class	
GO:0001723	biolink:NamedThing	obsolete type II intermediate filament associated protein	OBSOLETE. High molecular weight (100-300 kDa) proteins that associate with intermediate filaments to cross-link them into loose networks.	got7fsn_ti	type II intermediate filament associated protein			GO:0005882	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:1903571	biolink:NamedThing	negative regulation of protein kinase D signaling	Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling.	got7fsn_ti	negative regulation of protein kinase D signalling cascade|negative regulation of protein kinase D signaling cascade|down regulation of protein kinase D signalling cascade|downregulation of protein kinase D signaling|inhibition of protein kinase D signalling cascade|negative regulation of PKD signal transduction|inhibition of PKD signaling cascade|negative regulation of protein kinase D signal transduction|down-regulation of PKD signal transduction|down regulation of PKD signal transduction|down regulation of protein kinase D signal transduction|inhibition of protein kinase D signaling cascade|inhibition of PKD signal transduction|downregulation of protein kinase D signal transduction|downregulation of PKD signaling cascade|down regulation of protein kinase D signaling cascade|downregulation of PKD signal transduction|inhibition of protein kinase D signal transduction|down-regulation of protein kinase D signalling cascade|inhibition of protein kinase D signaling|down-regulation of PKD signaling cascade|downregulation of protein kinase D signalling cascade|downregulation of protein kinase D signaling cascade|down-regulation of protein kinase D signal transduction|down regulation of protein kinase D signaling|down-regulation of protein kinase D signaling cascade|down-regulation of protein kinase D signaling|negative regulation of PKD signaling cascade|down regulation of PKD signaling cascade						rl	2014-10-27T15:18:10Z						biological_process											owl:Class	
GO:1903360	biolink:NamedThing	protein localization to lateral cortical node	A process in which a protein is transported to, or maintained in, a location within a lateral cortical node.	got7fsn_ti	protein localization in lateral cortical node|protein localisation to lateral cortical node|protein localisation in lateral cortical node						mah	2014-08-21T10:23:00Z						biological_process											owl:Class	
GO:1904965	biolink:NamedThing	regulation of vitamin E biosynthetic process	Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process.	got7fsn_ti	regulation of vitamin E formation|regulation of tocopherol biosynthesis|regulation of alpha-tocopherol biosynthesis|regulation of vitamin E synthesis|regulation of vitamin E biosynthesis|regulation of alpha-tocopherol biosynthetic process|regulation of vitamin E anabolism|regulation of tocopherol biosynthetic process						tb	2016-02-12T17:56:55Z						biological_process											owl:Class	
GO:0140260	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex binding	Binding to a mitochondrial proton-transporting ATP synthase complex.	got7fsn_ti							pg	2018-09-10T19:38:26Z						molecular_function											owl:Class	
GO:0042842	biolink:NamedThing	D-xylose biosynthetic process	The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.	got7fsn_ti	D-xylose synthesis|D-xylose anabolism|D-xylose formation|D-xylose biosynthesis													biological_process											owl:Class	
GO:0090238	biolink:NamedThing	positive regulation of arachidonic acid secretion	Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.	got7fsn_ti							tb	2010-01-20T03:32:22Z						biological_process											owl:Class	
GO:0030457	biolink:NamedThing	obsolete activation of MAPKK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of MAPKK (mating sensu Fungi)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0004207	biolink:NamedThing	obsolete effector caspase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	effector caspase activity			GO:0004197	This term was made obsolete because it includes biological process information.	GO:0006915				True				molecular_function											owl:Class	
GO:0101007	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to salt stress	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12739			This term was obsoleted because it represents a GO-CAM model.	GO:0071472|GO:0000122	mec			True				biological_process											owl:Class	
GO:0032000	biolink:NamedThing	positive regulation of fatty acid beta-oxidation	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.	got7fsn_ti	upregulation of fatty acid beta-oxidation|activation of fatty acid beta-oxidation|up-regulation of fatty acid beta-oxidation|stimulation of fatty acid beta-oxidation|up regulation of fatty acid beta-oxidation													biological_process											owl:Class	
GO:0001320	biolink:NamedThing	obsolete age-dependent response to reactive oxygen species involved in chronological cell aging	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.	got7fsn_ti	age-dependent response to reactive oxidative species during chronological cell aging|age-dependent response to reactive oxygen species during chronological cell ageing|age-dependent response to reactive oxygen intermediate during chronological cell aging|age-dependent response to AOS during chronological cell aging|age-dependent response to reactive oxygen species during chronological cell aging|age-dependent response to active oxygen species during chronological cell aging|age-dependent response to ROS during chronological cell aging|age-dependent response to ROI during chronological cell aging	https://github.com/geneontology/go-ontology/issues/18632			This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398				True				biological_process											owl:Class	
GO:2001248	biolink:NamedThing	regulation of ammonia assimilation cycle	Any process that modulates the frequency, rate or extent of ammonia assimilation cycle.	got7fsn_ti	regulation of glutamate metabolism via glutamine and ammonia|regulation of glutamate metabolic process via glutamine and ammonia						rl	2011-12-01T10:08:21Z						biological_process											owl:Class	
GO:1902640	biolink:NamedThing	propan-2-ol biosynthetic process	The chemical reactions and pathways resulting in the formation of propan-2-ol.	got7fsn_ti	Isopropyl alcohol biosynthetic process|propan-2-ol synthesis|propan-2-ol formation|propan-2-ol biosynthesis|propan-2-ol anabolism|Isopropanol biosynthetic process						tt	2014-01-21T13:57:22Z						biological_process											owl:Class	
GO:1901552	biolink:NamedThing	positive regulation of endothelial cell development	Any process that activates or increases the frequency, rate or extent of endothelial cell development.	got7fsn_ti	up regulation of endothelial cell development|activation of endothelial cell development|up-regulation of endothelial cell development|upregulation of endothelial cell development						pr	2012-10-30T12:59:58Z						biological_process											owl:Class	
GO:0050861	biolink:NamedThing	positive regulation of B cell receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.	got7fsn_ti	positive regulation of B lymphocyte receptor signaling pathway|up regulation of B cell receptor signaling pathway|positive regulation of B lymphocyte receptor signalling pathway|up-regulation of B cell receptor signaling pathway|positive regulation of B-lymphocyte receptor signaling pathway|positive regulation of B-lymphocyte receptor signalling pathway|stimulation of B cell receptor signaling pathway|positive regulation of B cell receptor signalling pathway|upregulation of B cell receptor signaling pathway|positive regulation of B-cell receptor signalling pathway|positive regulation of B-cell receptor signaling pathway|activation of B cell receptor signaling pathway													biological_process											owl:Class	
GO:2001083	biolink:NamedThing	alpha-D-glucan binding	Binding to alpha-D-glucan.	got7fsn_ti							jl	2011-09-15T01:26:14Z						molecular_function											owl:Class	
GO:1901293	biolink:NamedThing	nucleoside phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.	got7fsn_ti	nucleoside phosphate biosynthesis|nucleoside phosphate synthesis|nucleoside phosphate formation|nucleoside phosphate anabolism						bf	2012-08-20T12:33:45Z						biological_process											owl:Class	
GO:1902137	biolink:NamedThing	(-)-secoisolariciresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol.	got7fsn_ti	(-)-secoisolariciresinol catabolism|(-)-secoisolariciresinol degradation|(-)-secoisolariciresinol breakdown						ms	2013-05-21T08:50:24Z						biological_process											owl:Class	
GO:1904731	biolink:NamedThing	positive regulation of intestinal lipid absorption	Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption.	got7fsn_ti	up-regulation of intestinal lipid absorption|up regulation of intestinal lipid absorption|activation of intestinal lipid absorption|upregulation of intestinal lipid absorption						sl	2015-10-14T15:25:10Z						biological_process											owl:Class	
GO:0030363	biolink:NamedThing	obsolete pre-mRNA cleavage factor activity	OBSOLETE. Any activity required for the process of mRNA cleavage.	got7fsn_ti	pre-mRNA cleavage factor activity				This term was made obsolete because it describes a biological process.	GO:0006379				True				molecular_function											owl:Class	
GO:0016911	biolink:NamedThing	obsolete SAP kinase 4 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	SAP kinase 4 activity|SAPK4				This term was made obsolete because it describes a gene product.	GO:0007254|GO:0004674				True				molecular_function											owl:Class	
GO:1903504	biolink:NamedThing	regulation of mitotic spindle checkpoint	Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.	got7fsn_ti	regulation of mitotic cell cycle spindle checkpoint				Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation or Dma1-dependent).		al	2014-10-01T13:52:57Z						biological_process											owl:Class	
GO:0045713	biolink:NamedThing	obsolete low-density lipoprotein particle receptor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells.	got7fsn_ti	low-density lipoprotein receptor anabolism|low-density lipoprotein receptor formation|LDLr biosynthetic process|LDLr biosynthesis|low-density lipoprotein receptor biosynthesis|low-density lipoprotein receptor synthesis|low-density lipoprotein receptor biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0071995	biolink:NamedThing	phytochelatin import into vacuole	The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.	got7fsn_ti	cadystin import into vacuole|phytochelatin transport into vacuole						mah	2010-10-25T02:01:59Z						biological_process											owl:Class	
GO:0009569	biolink:NamedThing	chloroplast starch grain	Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.	got7fsn_ti	chloroplast starch granule													cellular_component											owl:Class	
GO:2000628	biolink:NamedThing	regulation of miRNA metabolic process	Any process that modulates the frequency, rate or extent of miRNA metabolic process.	got7fsn_ti	regulation of microRNA metabolic process						dph	2011-04-18T03:47:54Z						biological_process											owl:Class	
GO:1901533	biolink:NamedThing	negative regulation of hematopoietic progenitor cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation.	got7fsn_ti	downregulation of haemopoietic progenitor cell differentiation|downregulation of hematopoietic progenitor cell differentiation|inhibition of hematopoietic progenitor cell differentiation|down-regulation of haematopoietic progenitor cell differentiation|down-regulation of hemopoietic progenitor cell differentiation|inhibition of haematopoietic progenitor cell differentiation|negative regulation of hemopoietic progenitor cell differentiation|down-regulation of haemopoietic progenitor cell differentiation|down regulation of haematopoietic progenitor cell differentiation|inhibition of hemopoietic progenitor cell differentiation|negative regulation of haemopoietic progenitor cell differentiation|down regulation of hematopoietic progenitor cell differentiation|down-regulation of hematopoietic progenitor cell differentiation|down regulation of haemopoietic progenitor cell differentiation|inhibition of haemopoietic progenitor cell differentiation|downregulation of hemopoietic progenitor cell differentiation|down regulation of hemopoietic progenitor cell differentiation|negative regulation of haematopoietic progenitor cell differentiation|downregulation of haematopoietic progenitor cell differentiation						vk	2012-10-24T11:23:06Z						biological_process											owl:Class	
GO:0046759	biolink:NamedThing	obsolete lytic virus budding from plasma membrane	OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host nuclear membrane system, resulting in envelopment of the virus and cell lysis.	got7fsn_ti	lytic viral budding from plasma membrane|lytic virus budding from plasma membrane|lytic plasma membrane viral budding				This term was made obsolete because it does not appear to correspond to a real biological process.					True				biological_process											owl:Class	
GO:1904038	biolink:NamedThing	regulation of iron export across plasma membrane	Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	regulation of iron(2+) export|regulation of ferrous iron export						kom	2015-03-16T15:36:37Z						biological_process											owl:Class	
GO:1903699	biolink:NamedThing	tarsal gland development	The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure.	got7fsn_ti	Meibomian gland development|glandula tarsales development|tarsoconjunctival gland development|gland of Meibom development						cls	2014-12-03T11:47:07Z						biological_process											owl:Class	
GO:2000612	biolink:NamedThing	regulation of thyroid-stimulating hormone secretion	Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion.	got7fsn_ti	regulation of TSH secretion|regulation of thyroid stimulating hormone secretion						yaf	2011-04-18T12:56:16Z						biological_process											owl:Class	
GO:1900416	biolink:NamedThing	obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of 4,6-pyruvylated galactose residue biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T03:42:41Z		True				biological_process											owl:Class	
GO:1904080	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in neuron fate specification	OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron fate specification.	got7fsn_ti	activation of global transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of transcription from RNA polymerase II promoter, global involved in neuron fate specification|activation of transcription from RNA polymerase II promoter involved in neuron fate specification|upregulation of transcription from RNA polymerase II promoter involved in neuron fate specification|up regulation of transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron fate specification|up-regulation of transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of global transcription from Pol II promoter involved in neuron fate specification|stimulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|stimulation of transcription from RNA polymerase II promoter involved in neuron fate specification|up-regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|upregulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of transcription from Pol II promoter involved in neuron fate specification|up regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification				This term was obsoleted because it represents a GO-CAM model.	GO:0048665|GO:0045944	kmv	2015-03-24T18:56:50Z		True				biological_process											owl:Class	
GO:1903642	biolink:NamedThing	regulation of recombination hotspot binding	Any process that modulates the frequency, rate or extent of recombination hotspot binding.	got7fsn_ti	regulation of DNA binding, recombination hotspot						al	2014-11-21T12:02:22Z						biological_process											owl:Class	
GO:0042154	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061487	biolink:NamedThing	obsolete DNA replication initiation from late origin	OBSOLETE. The process in which DNA-dependent DNA replication is started at a late origin of replication. A late origin of replication refers to an origin that is activated late in S phase.	got7fsn_ti	late replication origin firing				The reason for obsoletion is that there is no evidence that this is a different process from its parent term (DNA replication initiation, GO:0006270), but only that regulation of initiation at late origins differs from regulation of initiation at early origins.	GO:0101017	dph	2012-12-06T11:21:48Z		True				biological_process											owl:Class	
GO:0010626	biolink:NamedThing	negative regulation of Schwann cell proliferation	Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:1901786	biolink:NamedThing	p-cresol biosynthetic process	The chemical reactions and pathways resulting in the formation of p-cresol.	got7fsn_ti	p-cresol formation|p-cresol anabolism|p-cresol biosynthesis|p-cresol synthesis						yaf	2013-01-16T11:04:08Z						biological_process											owl:Class	
GO:0001040	biolink:NamedThing	obsolete RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	got7fsn_ti					The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter.		krc	2010-08-23T06:28:23Z		True				molecular_function											owl:Class	
GO:0009380	biolink:NamedThing	excinuclease repair complex	Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.	got7fsn_ti	UvrABC excinuclease complex|excinuclease ABC complex													cellular_component											owl:Class	
GO:0150180	biolink:NamedThing	negative regulation of phosphatidylserine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process.	got7fsn_ti							bc	2020-01-21T14:06:06Z						biological_process											owl:Class	
GO:0002597	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.	got7fsn_ti	up regulation of antigen processing and presentation of peptide antigen via MHC class Ib|positive regulation of peptide antigen processing and presentation via MHC class Ib|activation of antigen processing and presentation of peptide antigen via MHC class Ib|up-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|upregulation of antigen processing and presentation of peptide antigen via MHC class Ib|stimulation of antigen processing and presentation of peptide antigen via MHC class Ib													biological_process											owl:Class	
GO:1903413	biolink:NamedThing	cellular response to bile acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.	got7fsn_ti							rl	2014-09-03T12:45:51Z						biological_process											owl:Class	
GO:1905228	biolink:NamedThing	positive regulation of adhesion of symbiont to host epithelial cell	Any process that activates or increases the frequency, rate or extent of adhesion of symbiont to host epithelial cell.	got7fsn_ti	upregulation of adhesion of symbiont to host epithelial cell|activation of adhesion of symbiont to host epithelial cell|up regulation of adhesion of symbiont to host epithelial cell|up-regulation of adhesion of symbiont to host epithelial cell						pga	2016-06-07T13:15:24Z						biological_process											owl:Class	
GO:0090092	biolink:NamedThing	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.	got7fsn_ti	regulation of transmembrane receptor protein serine/threonine kinase signalling pathway						tb	2009-11-04T11:46:40Z						biological_process											owl:Class	
GO:0043518	biolink:NamedThing	negative regulation of DNA damage response, signal transduction by p53 class mediator	Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.	got7fsn_ti	downregulation of DNA damage response, signal transduction by p53 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator|negative regulation of p53 induced by DNA damage response|down regulation of DNA damage response, signal transduction by p53 class mediator|down-regulation of DNA damage response, signal transduction by p53 class mediator													biological_process											owl:Class	
GO:0018980	biolink:NamedThing	2,4,5-trichlorophenoxyacetic acid metabolic process	The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns.	got7fsn_ti	2,4,5-trichlorophenoxyacetic acid metabolism|2,4,5-T metabolic process|2,4,5-T metabolism											UM-BBD_pathwayID:2,4,5-t		biological_process											owl:Class	
GO:1901703	biolink:NamedThing	protein localization involved in auxin polar transport	Any protein localization that is involved in auxin polar transport.	got7fsn_ti	establishment and maintenance of protein localization involved in auxin polar transport|protein localisation involved in auxin polar transport						tb	2012-12-13T19:06:13Z						biological_process											owl:Class	
GO:0015983	biolink:NamedThing	obsolete symport	OBSOLETE. The process of solute translocation in which two solutes equilibrate across an osmotic barrier, and the translocation of one solute is coupled to the translocation of the other in the same direction.	got7fsn_ti	symport			GO:0015293	This term was made obsolete because it represents a molecular function rather than a biological process.					True				biological_process											owl:Class	
GO:0048075	biolink:NamedThing	positive regulation of eye pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.	got7fsn_ti	upregulation of eye pigmentation|up-regulation of eye pigmentation|stimulation of eye pigmentation|activation of eye pigmentation|up regulation of eye pigmentation													biological_process											owl:Class	
GO:1904830	biolink:NamedThing	negative regulation of aortic smooth muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation.	got7fsn_ti	down-regulation of aortic smooth muscle cell differentiation|inhibition of aortic smooth muscle cell differentiation|down regulation of aortic smooth muscle cell differentiation|downregulation of aortic smooth muscle cell differentiation						rph	2015-11-24T10:20:47Z						biological_process											owl:Class	
GO:0001206	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900924	biolink:NamedThing	negative regulation of glycine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell.	got7fsn_ti	inhibition of glycine import|down regulation of glycine import|downregulation of glycine import|down-regulation of glycine import|negative regulation of glycine import						al	2012-06-13T07:40:32Z						biological_process											owl:Class	
GO:0019463	biolink:NamedThing	glycine catabolic process to creatine	The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine.	got7fsn_ti	glycine degradation to creatine|glycine breakdown to creatine											MetaCyc:GLYCGREAT-PWY		biological_process											owl:Class	
GO:1904016	biolink:NamedThing	response to Thyroglobulin triiodothyronine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.	got7fsn_ti							sl	2015-03-06T19:34:07Z						biological_process											owl:Class	
GO:2000163	biolink:NamedThing	regulation of planar cell polarity pathway involved in outflow tract morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.	got7fsn_ti							dph	2010-10-05T01:06:13Z						biological_process											owl:Class	
GO:1901825	biolink:NamedThing	zeaxanthin metabolic process	The chemical reactions and pathways involving zeaxanthin.	got7fsn_ti	zeaxanthin metabolism						yaf	2013-01-22T11:36:55Z						biological_process											owl:Class	
GO:0075207	biolink:NamedThing	obsolete negative regulation by host of symbiont cAMP-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by host of symbiont cAMP-mediated signaling				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0032572	biolink:NamedThing	response to menaquinone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.	got7fsn_ti	response to vitamin K2|response to menatetrenone													biological_process											owl:Class	
GO:1905784	biolink:NamedThing	regulation of anaphase-promoting complex-dependent catabolic process	Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.	got7fsn_ti							vw	2017-01-09T10:16:14Z						biological_process											owl:Class	
GO:0035636	biolink:NamedThing	obsolete multi-organism signaling	OBSOLETE. The transfer of information between living organisms.	got7fsn_ti	signaling between organisms|signaling with other organism|multi-organism signalling|pheromone signaling				This term was obsoleted because it was a grouping term but had no subclasses.		bf	2011-01-14T10:11:25Z		True				biological_process											owl:Class	
GO:0009125	biolink:NamedThing	nucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	nucleoside monophosphate breakdown|nucleoside monophosphate degradation|nucleoside monophosphate catabolism													biological_process											owl:Class	
GO:0070641	biolink:NamedThing	vitamin D4 metabolic process	The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.	got7fsn_ti	vitamin D4 metabolism						mah	2009-05-08T02:33:01Z						biological_process											owl:Class	
GO:0019023	biolink:NamedThing	obsolete dsRNA viral genome	OBSOLETE. A viral genome composed of double stranded RNA.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
CHEBI:17933	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007471	biolink:NamedThing	obsolete prothoracic morphogenesis	OBSOLETE. The process by which the anatomical structures of the first or anterior segment of the insect thorax are generated and organized.	got7fsn_ti	prothoracic morphogenesis				This term was made obsolete because it does not stipulate which anatomical part is involved in the process.	GO:0007470				True				biological_process											owl:Class	
GO:0009939	biolink:NamedThing	positive regulation of gibberellic acid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity.	got7fsn_ti	positive regulation of gibberellic acid mediated signalling|activation of gibberellic acid mediated signaling|upregulation of gibberellic acid mediated signaling|up-regulation of gibberellic acid mediated signaling|stimulation of gibberellic acid mediated signaling|up regulation of gibberellic acid mediated signaling													biological_process											owl:Class	
GO:1904196	biolink:NamedThing	negative regulation of granulosa cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation.	got7fsn_ti	down regulation of granulosa cell proliferation|downregulation of granulosa cell proliferation|down-regulation of granulosa cell proliferation|inhibition of granulosa cell proliferation						sl	2015-05-07T17:02:34Z						biological_process											owl:Class	
GO:1903555	biolink:NamedThing	regulation of tumor necrosis factor superfamily cytokine production	Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.	got7fsn_ti	regulation of TNF superfamily production|regulation of TNFSF cytokine production						pga	2014-10-21T10:26:05Z						biological_process											owl:Class	
GO:0033611	biolink:NamedThing	oxalate catabolic process	The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.	got7fsn_ti	oxalate breakdown|oxalic acid catabolic process|ethanedioate catabolic process|oxalate degradation|oxalate catabolism|ethanedioic acid catabolic process													biological_process											owl:Class	
GO:0004247	biolink:NamedThing	obsolete saccharolysin activity	OBSOLETE. Catalysis of the cleavage of Pro-Phe and Ala-Ala bonds.	got7fsn_ti	proteinase yscD activity|saccharolysin activity|saccharomyces cerevisiae proteinase yscD|yeast cysteine proteinase D activity|oligopeptidase yscD activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1990495	biolink:NamedThing	obsolete actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly	OBSOLETE. An actin filament organization process that contributes to actomyosin contractile ring assembly during mitotic cytokinesis.	got7fsn_ti	actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-09-25T09:19:27Z		True				biological_process											owl:Class	
GO:0032149	biolink:NamedThing	response to rhamnose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.	got7fsn_ti	response to L-rhamnose stimulus|response to rhamnose stimulus													biological_process											owl:Class	
GO:0005995	biolink:NamedThing	melibiose catabolic process	The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.	got7fsn_ti	melibiose degradation|melibiose catabolism|melibiose breakdown													biological_process											owl:Class	
GO:1902136	biolink:NamedThing	(-)-secoisolariciresinol metabolic process	The chemical reactions and pathways involving (-)-secoisolariciresinol.	got7fsn_ti	(-)-secoisolariciresinol metabolism						ms	2013-05-21T08:50:19Z						biological_process											owl:Class	
GO:0000292	biolink:NamedThing	RNA fragment catabolic process	The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.	got7fsn_ti	RNA fragment catabolism|RNA fragment degradation|group I intron catabolic process|RNA fragment breakdown										GO:0030452			biological_process											owl:Class	
GO:0035392	biolink:NamedThing	obsolete maintenance of chromatin silencing at telomere	OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19301			This term was obsoleted because it represented a phenotype.		bf	2010-03-22T10:25:57Z		True				biological_process											owl:Class	
GO:0004290	biolink:NamedThing	obsolete kexin activity	OBSOLETE. Catalysis of the cleavage of the Arg-Xaa bond in Lys-Arg-Xaa and Arg-Arg-Xaa to process Yeast alpha-factor pheromone and killer toxin precursors.	got7fsn_ti	prohormone-processing endoprotease activity|yeast cysteine proteinase F|protease KEX2|Kex2 endoproteinase|endoproteinase Kex2p|proteinase Kex2p|Kex2 protease|Kex2-like precursor protein processing endoprotease|andrenorphin-Gly-generating enzyme|Kex2 endopeptidase|kexin activity|Kex2 endoprotease|Kex 2p proteinase|prohormone-processing proteinase activity|gene KEX2 dibasic proteinase|Kex2 proteinase|proteinase yscF activity|paired-basic endopeptidase activity|prohormone-processing KEX2 proteinase|yeast KEX2 protease activity|Kex2-like endoproteinase			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0032712	biolink:NamedThing	negative regulation of interleukin-3 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production.	got7fsn_ti	negative regulation of interleukin-3 biosynthetic process|downregulation of interleukin-3 production|inhibition of interleukin-3 production|down-regulation of interleukin-3 production|down regulation of interleukin-3 production|negative regulation of IL-3 production										GO:0045400			biological_process											owl:Class	
GO:1903693	biolink:NamedThing	obsolete regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation.	got7fsn_ti	regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/20989			This term was obsoleted because it does not represent a specific process.		al	2014-12-02T18:16:03Z		True				biological_process											owl:Class	
GO:0009697	biolink:NamedThing	salicylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.	got7fsn_ti	salicylic acid anabolism|salicylate biosynthetic process|salicylic acid synthesis|salicylic acid biosynthesis|salicylic acid formation											MetaCyc:PWY-981		biological_process											owl:Class	
GO:0072734	biolink:NamedThing	cellular response to staurosporine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.	got7fsn_ti							mah	2012-07-17T10:33:00Z						biological_process											owl:Class	
GO:1901757	biolink:NamedThing	butirosin catabolic process	The chemical reactions and pathways resulting in the breakdown of butirosin.	got7fsn_ti	butirosin catabolism|butirosin degradation|butirosin breakdown						yaf	2013-01-14T11:36:22Z						biological_process											owl:Class	
GO:0046109	biolink:NamedThing	uridine biosynthetic process	The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.	got7fsn_ti	uridine formation|uridine anabolism|uridine biosynthesis|uridine synthesis													biological_process											owl:Class	
GO:0071590	biolink:NamedThing	nicotinamide riboside biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.	got7fsn_ti	nicotinamide riboside biosynthesis|nicotinamide riboside formation|nicotinamide riboside anabolism|nicotinamide riboside synthesis|N-ribosylnicotinamide biosynthetic process						mah	2010-01-29T11:39:27Z						biological_process											owl:Class	
GO:2000491	biolink:NamedThing	positive regulation of hepatic stellate cell activation	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.	got7fsn_ti							bf	2011-03-14T03:49:48Z						biological_process											owl:Class	
GO:1904037	biolink:NamedThing	positive regulation of epithelial cell apoptotic process	Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process.	got7fsn_ti	up-regulation of epitheliocyte apoptotic process|positive regulation of epithelial cell apoptosis|upregulation of epithelial cell apoptotic process|up-regulation of epithelial cell apoptosis|up regulation of epithelial cell apoptotic process|activation of epithelial cell apoptosis|up-regulation of epitheliocyte apoptosis|activation of epitheliocyte apoptotic process|up-regulation of epithelial cell apoptotic process|up regulation of epithelial cell apoptosis|activation of epithelial cell apoptotic process|positive regulation of epitheliocyte apoptotic process|upregulation of epithelial cell apoptosis|upregulation of epitheliocyte apoptosis|up regulation of epitheliocyte apoptosis|upregulation of epitheliocyte apoptotic process|positive regulation of epitheliocyte apoptosis|activation of epitheliocyte apoptosis|up regulation of epitheliocyte apoptotic process						sl	2015-03-13T22:05:53Z						biological_process											owl:Class	
UBERON:0004804	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034096	biolink:NamedThing	positive regulation of maintenance of meiotic sister chromatid cohesion	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
CHEBI:12931	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048026	biolink:NamedThing	positive regulation of mRNA splicing, via spliceosome	Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.	got7fsn_ti	up regulation of nuclear mRNA splicing, via spliceosome|positive regulation of pre-mRNA splicing|activation of nuclear mRNA splicing via U2-type spliceosome|positive regulation of nuclear mRNA splicing via U2-type spliceosome|stimulation of nuclear mRNA splicing, via spliceosome|stimulation of nuclear mRNA splicing via U2-type spliceosome|upregulation of nuclear mRNA splicing, via spliceosome|activation of nuclear mRNA splicing, via spliceosome|up-regulation of nuclear mRNA splicing via U2-type spliceosome|up-regulation of nuclear mRNA splicing, via spliceosome|upregulation of nuclear mRNA splicing via U2-type spliceosome|positive regulation of nuclear mRNA splicing, via spliceosome|up regulation of nuclear mRNA splicing via U2-type spliceosome										GO:0035057			biological_process											owl:Class	
GO:0003275	biolink:NamedThing	apoptotic process involved in outflow tract morphogenesis	Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.	got7fsn_ti	apoptosis involved in outflow tract morphogenesis						dph	2009-10-20T09:30:01Z						biological_process											owl:Class	
GO:2000585	biolink:NamedThing	positive regulation of platelet-derived growth factor receptor-alpha signaling pathway	Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.	got7fsn_ti	positive regulation of PDGFR-alpha signaling pathway|positive regulation of alphaPDGF receptor signaling pathway|positive regulation of PDGF receptor-alpha signaling pathway|positive regulation of platelet-derived growth factor receptor-alpha signalling pathway						bf	2011-04-07T03:26:35Z						biological_process											owl:Class	
GO:0035957	biolink:NamedThing	obsolete positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the breakdown of starch, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of starch catabolic process by regulation of transcription from Pol II promoter|positive regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter|positive regulation of starch catabolism by regulation of transcription from Pol II promoter|positive regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter|positive regulation of starch degradation by regulation of transcription from RNA polymerase II promoter|positive regulation of starch degradation by regulation of transcription from Pol II promoter|positive regulation of starch breakdown by regulation of transcription from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0032557	biolink:NamedThing	pyrimidine ribonucleotide binding	Binding to a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	got7fsn_ti														molecular_function											owl:Class	
GO:1901483	biolink:NamedThing	regulation of transcription factor catabolic process	Any process that modulates the frequency, rate or extent of transcription factor catabolic process.	got7fsn_ti	regulation of transcription factor catabolism|regulation of transcription factor breakdown|regulation of proteasome-mediated transcription factor catabolism|regulation of transcription factor degradation|regulation of sequence-specific DNA binding transcription factor catabolic process						bf	2012-10-08T09:03:18Z						biological_process											owl:Class	
GO:1990347	biolink:NamedThing	obsolete G*/A mismatch-specific adenine-DNA glycosylase activity	OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite 8-oxoG in the template by adenine DNA glycosylase activity. The reaction leaves an apyrimidinic (AP) site.	got7fsn_ti	G*/A mismatch-specific adenine-DNA glycosylase activity				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-03-25T10:14:37Z		True				molecular_function											owl:Class	
GO:0015315	biolink:NamedThing	organophosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out).	got7fsn_ti														molecular_function											owl:Class	
GO:1904482	biolink:NamedThing	cellular response to tetrahydrofolate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.	got7fsn_ti							hal	2015-07-14T14:49:23Z						biological_process											owl:Class	
GO:1901488	biolink:NamedThing	obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process	OBSOLETE. Negative regulation of transcription factor catabolism that results in positive regulation of the SREBP signaling pathway.	got7fsn_ti	positive regulation of SREBP-mediated signalling pathway by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolism|positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation|positive regulation of SREBP signaling pathway by inhibition of SREBP degradation|positive regulation of SREBP-mediated signaling pathway by negative regulation of transcription factor catabolic process				The reason for obsoletion is that this term should be represented by a GO-CAM model.		bf	2012-10-09T08:23:43Z		True				biological_process											owl:Class	
GO:1904369	biolink:NamedThing	positive regulation of sclerenchyma cell differentiation	Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation.	got7fsn_ti	upregulation of sclerenchyma cell differentiation|up regulation of sclerenchyma cell differentiation|up-regulation of sclerenchyma cell differentiation						tb	2015-06-17T19:53:06Z						biological_process											owl:Class	
GO:0071450	biolink:NamedThing	cellular response to oxygen radical	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.	got7fsn_ti							mah	2009-12-16T04:38:52Z						biological_process											owl:Class	
GO:1905628	biolink:NamedThing	negative regulation of serotonin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.	got7fsn_ti	inhibition of serotonin biosynthetic process|down-regulation of serotonin anabolism|negative regulation of serotonin biosynthesis|negative regulation of serotonin formation|downregulation of serotonin anabolism|down regulation of serotonin formation|downregulation of serotonin formation|downregulation of serotonin synthesis|inhibition of serotonin biosynthesis|downregulation of serotonin biosynthetic process|down-regulation of serotonin biosynthetic process|down regulation of serotonin biosynthetic process|negative regulation of serotonin anabolism|inhibition of serotonin formation|down regulation of serotonin anabolism|downregulation of serotonin biosynthesis|inhibition of serotonin synthesis|down regulation of serotonin synthesis|down regulation of serotonin biosynthesis|down-regulation of serotonin synthesis|inhibition of serotonin anabolism|down-regulation of serotonin biosynthesis|down-regulation of serotonin formation|negative regulation of serotonin synthesis						pad	2016-10-31T14:26:28Z						biological_process											owl:Class	
GO:0015466	biolink:NamedThing	obsolete autolysin activity	OBSOLETE. An agent that can lyse the cell in which it is synthesized.	got7fsn_ti	autolysin activity				This term was made obsolete because it represents a class of gene products.	GO:0019835				True				molecular_function											owl:Class	
GO:0052417	biolink:NamedThing	obsolete metabolism by host of symbiont protein	OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1900838	biolink:NamedThing	negative regulation of fumigaclavine C biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process.	got7fsn_ti	inhibition of fumigaclavine C biosynthetic process						di	2012-06-07T09:36:45Z						biological_process											owl:Class	
CHEBI:60974	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903969	biolink:NamedThing	regulation of response to macrophage colony-stimulating factor	Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor.	got7fsn_ti	regulation of response to M-CSF|regulation of response to macrophage colony-stimulating factor|regulation of response to macrophage colony-stimulating factor stimulus						nc	2015-03-02T14:41:02Z						biological_process											owl:Class	
GO:0046227	biolink:NamedThing	obsolete 2,4,5-trichlorophenoxyacetic acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.	got7fsn_ti	2,4,5-trichlorophenoxyacetic acid biosynthetic process|2,4,5-trichlorophenoxyacetic acid biosynthesis|2,4,5-trichlorophenoxyacetic acid anabolism|2,4,5-trichlorophenoxyacetic acid formation|2,4,5-trichlorophenoxyacetic acid synthesis			GO:0018980	This term was made obsolete because 2,4,5-trichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0071631	biolink:NamedThing	mating pheromone secretion involved in positive regulation of conjugation with cellular fusion	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types.	got7fsn_ti	mating-type pheromone secretion involved in conjugation with cellular fusion						mah	2010-02-11T03:36:57Z						biological_process											owl:Class	
GO:1903742	biolink:NamedThing	regulation of anterograde synaptic vesicle transport	Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.	got7fsn_ti							kmv	2014-12-12T16:28:27Z						biological_process											owl:Class	
GO:1900419	biolink:NamedThing	regulation of cellular alcohol catabolic process	Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process.	got7fsn_ti							krc	2012-04-20T10:21:18Z						biological_process											owl:Class	
GO:1900783	biolink:NamedThing	fumiquinazoline F catabolic process	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline F.	got7fsn_ti	fumiquinazoline F breakdown|fumiquinazoline F degradation|fumiquinazoline F catabolism						di	2012-06-04T09:31:27Z						biological_process											owl:Class	
GO:1900368	biolink:NamedThing	regulation of RNA interference	Any process that modulates the frequency, rate or extent of RNA interference.	got7fsn_ti	regulation of RNAi|regulation of posttranscriptional gene silencing by siRNA						kmv	2012-04-13T08:28:39Z						biological_process											owl:Class	
GO:1903161	biolink:NamedThing	obsolete pantothenate transmembrane transporter activity involved in pantothenate import into cell	OBSOLETE. Any pantothenate transmembrane transporter activity that is involved in pantothenate import into cell.	got7fsn_ti	pantothenate transmembrane transporter activity involved in pantothenate import into cell|vitamin B5 transmembrane transporter activity involved in pantothenate import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:38Z		True				molecular_function											owl:Class	
GO:1904651	biolink:NamedThing	positive regulation of fat cell apoptotic process	Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process.	got7fsn_ti	activation of adipose cell apoptosis|up-regulation of adipose cell apoptosis|positive regulation of adipocyte apoptotic process|up-regulation of adipocyte apoptotic process|up regulation of adipose cell apoptosis|upregulation of adipocyte apoptotic process|upregulation of adipocyte apoptosis|positive regulation of adipose cell apoptotic process|up-regulation of fat cell apoptosis|positive regulation of fat cell apoptosis|positive regulation of adipocyte apoptosis|up regulation of fat cell apoptosis|up regulation of adipose cell apoptotic process|up regulation of adipocyte apoptosis|positive regulation of adipose cell apoptosis|up-regulation of adipose cell apoptotic process|upregulation of fat cell apoptotic process|upregulation of adipose cell apoptosis|activation of fat cell apoptotic process|activation of adipose cell apoptotic process|up-regulation of adipocyte apoptosis|upregulation of adipose cell apoptotic process|activation of fat cell apoptosis|upregulation of fat cell apoptosis|activation of adipocyte apoptosis|up-regulation of fat cell apoptotic process|activation of adipocyte apoptotic process|up regulation of fat cell apoptotic process|up regulation of adipocyte apoptotic process						sl	2015-08-31T20:59:40Z						biological_process											owl:Class	
GO:1900652	biolink:NamedThing	regulation of demethylkotanin biosynthetic process	Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process.	got7fsn_ti	regulation of demethylkotanin formation|regulation of demethylkotanin anabolism|regulation of demethylkotanin biosynthesis|regulation of demethylkotanin synthesis						di	2012-05-22T04:07:18Z						biological_process											owl:Class	
GO:0016252	biolink:NamedThing	obsolete nonspecific RNA polymerase II transcription factor activity	OBSOLETE. Any function that supports transcription of genes by RNA polymerase II, and is not specific to a particular gene or gene set.	got7fsn_ti	nonspecific RNA polymerase II transcription factor activity				This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0016251|GO:0006366				True				molecular_function											owl:Class	
GO:0001799	biolink:NamedThing	regulation of type IIb hypersensitivity	Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response.	got7fsn_ti														biological_process											owl:Class	
GO:1904790	biolink:NamedThing	regulation of shelterin complex assembly	Any process that modulates the frequency, rate or extent of shelterin complex assembly.	got7fsn_ti	regulation of telosome assembly|regulation of Pot1-Tpz1 complex assembly|regulation of Pot1 complex assembly|regulation of shelterin complex formation						nc	2015-11-06T16:13:03Z						biological_process											owl:Class	
GO:0070474	biolink:NamedThing	positive regulation of uterine smooth muscle contraction	Any process that increases the frequency, rate or extent of uterine smooth muscle contraction.	got7fsn_ti	positive regulation of myometrium contraction|positive regulation of myometrial contraction|up regulation of uterine smooth muscle contraction|stimulation of uterine smooth muscle contraction|up-regulation of uterine smooth muscle contraction|upregulation of uterine smooth muscle contraction|activation of uterine smooth muscle contraction|positive regulation of myometrial smooth muscle contraction													biological_process											owl:Class	
GO:1901799	biolink:NamedThing	negative regulation of proteasomal protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.	got7fsn_ti	down-regulation of proteasome-mediated protein catabolism|down-regulation of proteasome-mediated protein catabolic process|negative regulation of proteasome-mediated protein catabolism|inhibition of proteasome-mediated protein catabolism|down regulation of proteasomal protein catabolic process|downregulation of proteasomal protein catabolic process|down-regulation of proteasomal protein catabolic process|downregulation of proteasome-mediated protein catabolism|inhibition of proteasome-mediated protein catabolic process|down regulation of proteasome-mediated protein catabolic process|negative regulation of proteasome-mediated protein catabolic process|downregulation of proteasome-mediated protein catabolic process|down regulation of proteasome-mediated protein catabolism|inhibition of proteasomal protein catabolic process						rl	2013-01-21T20:10:54Z						biological_process											owl:Class	
GO:0048516	biolink:NamedThing	obsolete trichome initiation (sensu Magnoliophyta)	OBSOLETE. Processes causing the differentiation of an epidermal cell into a trichome cell; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398).	got7fsn_ti	trichome initiation (sensu Magnoliophyta)				This term was made obsolete because more appropriate terms were created.	GO:0048629				True				biological_process											owl:Class	
GO:0002599	biolink:NamedThing	negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.	got7fsn_ti	inhibition of antigen processing and presentation of lipid antigen via MHC class Ib|down regulation of antigen processing and presentation of lipid antigen via MHC class Ib|down-regulation of antigen processing and presentation of lipid antigen via MHC class Ib|downregulation of antigen processing and presentation of lipid antigen via MHC class Ib|negative regulation of lipid antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:1900886	biolink:NamedThing	positive regulation of tridecane biosynthetic process	Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process.	got7fsn_ti	activation of tridecane synthesis|up regulation of tridecane synthesis|activation of tridecane biosynthesis|upregulation of tridecane anabolism|up regulation of tridecane biosynthetic process|up regulation of tridecane biosynthesis|activation of tridecane formation|activation of tridecane biosynthetic process|activation of tridecane anabolism|up-regulation of tridecane anabolism|upregulation of tridecane biosynthetic process|up-regulation of tridecane biosynthesis|positive regulation of tridecane synthesis|up regulation of tridecane formation|upregulation of tridecane synthesis|up regulation of tridecane anabolism|positive regulation of tridecane biosynthesis|up-regulation of tridecane biosynthetic process|upregulation of tridecane biosynthesis|up-regulation of tridecane synthesis|positive regulation of tridecane anabolism|upregulation of tridecane formation|positive regulation of tridecane formation|up-regulation of tridecane formation						tt	2012-06-13T03:01:01Z						biological_process											owl:Class	
GO:1903251	biolink:NamedThing	multi-ciliated epithelial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell.	got7fsn_ti	multiciliate cell differentiation						tb	2014-08-05T19:21:21Z						biological_process											owl:Class	
GO:1902998	biolink:NamedThing	positive regulation of neurofibrillary tangle assembly	Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly.	got7fsn_ti	upregulation of star-shaped neurofibrillary tangle formation|up-regulation of flame-shaped neurofibrillary tangle formation|positive regulation of flame-shaped neurofibrillary tangle assembly|up-regulation of star-shaped neurofibrillary tangle assembly|activation of neurofibrillary tangle formation|positive regulation of flame-shaped neurofibrillary tangle formation|up regulation of neurofibrillary tangle assembly|up-regulation of flame-shaped neurofibrillary tangle assembly|up-regulation of neurofibrillary tangle formation|positive regulation of star-shaped neurofibrillary tangle assembly|positive regulation of star-shaped neurofibrillary tangle formation|up-regulation of neurofibrillary tangle assembly|up-regulation of star-shaped neurofibrillary tangle formation|upregulation of neurofibrillary tangle assembly|activation of star-shaped neurofibrillary tangle formation|up regulation of star-shaped neurofibrillary tangle formation|upregulation of flame-shaped neurofibrillary tangle formation|activation of star-shaped neurofibrillary tangle assembly|up regulation of neurofibrillary tangle formation|positive regulation of neurofibrillary tangle formation|up regulation of flame-shaped neurofibrillary tangle formation|up regulation of flame-shaped neurofibrillary tangle assembly|activation of neurofibrillary tangle assembly|activation of flame-shaped neurofibrillary tangle formation|up regulation of star-shaped neurofibrillary tangle assembly|upregulation of neurofibrillary tangle formation|upregulation of star-shaped neurofibrillary tangle assembly|upregulation of flame-shaped neurofibrillary tangle assembly|activation of flame-shaped neurofibrillary tangle assembly						sjp	2014-05-08T15:44:45Z						biological_process											owl:Class	
GO:0045973	biolink:NamedThing	positive regulation of juvenile hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone.	got7fsn_ti	activation of juvenile hormone secretion|up regulation of juvenile hormone secretion|stimulation of juvenile hormone secretion|upregulation of juvenile hormone secretion|up-regulation of juvenile hormone secretion													biological_process											owl:Class	
GO:0090310	biolink:NamedThing	negative regulation of DNA methylation-dependent heterochromatin assembly	Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.	got7fsn_ti	negative regulation of methylation-dependent chromatin silencing						tb	2010-04-09T02:12:53Z						biological_process											owl:Class	
GO:0006247	biolink:NamedThing	obsolete TTP reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	TTP reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051064				True				biological_process											owl:Class	
GO:2000036	biolink:NamedThing	regulation of stem cell population maintenance	Any process that modulates the frequency, rate or extent of stem cell population maintenance.	got7fsn_ti	regulation of maintenance of pluripotency						tb	2010-08-05T11:35:25Z						biological_process											owl:Class	
GO:0038067	biolink:NamedThing	obsolete MAP kinase activity involved in cell wall organization or biogenesis	OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.	got7fsn_ti	MAPK activity involved in cell wall biogenesis|MAP kinase activity involved in cell wall integrity|MAP kinase activity involved in cell wall biogenesis				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-25T03:29:04Z		True				molecular_function											owl:Class	
GO:1901099	biolink:NamedThing	negative regulation of signal transduction in absence of ligand	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand.	got7fsn_ti	inhibition of signal transduction in absence of ligand|down regulation of signal transduction in absence of agonist|down-regulation of basal signaling|downregulation of basal signaling|downregulation of signal transduction in absence of agonist|down regulation of non-classical signal transduction|downregulation of non-classical signal transduction|negative regulation of non-classical signal transduction|downregulation of signal transduction in absence of ligand|down-regulation of signal transduction in absence of agonist|down regulation of signal transduction in absence of ligand|down regulation of basal signaling|negative regulation of signal transduction in absence of agonist|down-regulation of signal transduction in absence of ligand|down-regulation of non-classical signal transduction						al	2012-07-10T10:31:08Z						biological_process											owl:Class	
GO:1905930	biolink:NamedThing	regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.	got7fsn_ti	regulation of VSMC differentiation involved in phenotypic switching|regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|regulation of VSMC differentiation involved in phenotypic dimorphism|regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism						rph	2017-02-09T09:20:59Z						biological_process											owl:Class	
GO:1901668	biolink:NamedThing	regulation of superoxide dismutase activity	Any process that modulates the frequency, rate or extent of superoxide dismutase activity.	got7fsn_ti	regulation of nickel superoxide oxidoreductase|regulation of Mn, Fe superoxide dismutase|regulation of SOD|regulation of nickel superoxide dismutase activity|regulation of SOD-4|regulation of Fe-SOD|regulation of manganese superoxide oxidoreductase|regulation of hepatocuprein|regulation of Mn-SOD|regulation of zinc superoxide oxidoreductase|regulation of copper, zinc superoxide dismutase activity|regulation of superoxide:superoxide oxidoreductase activity|regulation of SOD-2|regulation of Cu-Zn superoxide dismutase activity|regulation of SOD-1|regulation of superoxide dismutase I|regulation of SODS|regulation of cytocuprein|regulation of ferrisuperoxide dismutase activity|regulation of iron superoxide oxidoreductase|regulation of SODF|regulation of SOD-3|regulation of iron superoxide dismutase activity|regulation of cuprein|regulation of Cu,Zn-SOD|regulation of hemocuprein|regulation of manganese superoxide dismutase activity|regulation of erythrocuprein|regulation of superoxide dismutase II						tb	2012-11-21T20:46:42Z						biological_process											owl:Class	
GO:1904899	biolink:NamedThing	positive regulation of hepatic stellate cell proliferation	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.	got7fsn_ti	up-regulation of hepatic stellate cell proliferation|up regulation of Ito cell proliferation|up-regulation of hepatic perisinusoidal cell proliferation|positive regulation of hepatic perisinusoidal cell proliferation|upregulation of Ito cell proliferation|up-regulation of perisinusoidal cell proliferation|upregulation of hepatic perisinusoidal cell proliferation|upregulation of perisinusoidal cell proliferation|activation of perisinusoidal cell proliferation|up regulation of hepatic stellate cell proliferation|activation of hepatic stellate cell proliferation|upregulation of hepatic stellate cell proliferation|up-regulation of Ito cell proliferation|up regulation of perisinusoidal cell proliferation|activation of hepatic perisinusoidal cell proliferation|activation of Ito cell proliferation|up regulation of hepatic perisinusoidal cell proliferation|positive regulation of Ito cell proliferation|positive regulation of perisinusoidal cell proliferation						sl	2016-01-14T15:57:13Z						biological_process											owl:Class	
GO:0075024	biolink:NamedThing	obsolete phospholipase C-mediated activation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont phospholipase C-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1900483	biolink:NamedThing	regulation of protein targeting to vacuolar membrane	Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane.	got7fsn_ti							al	2012-05-02T10:13:23Z						biological_process											owl:Class	
GO:1904139	biolink:NamedThing	regulation of microglial cell migration	Any process that modulates the frequency, rate or extent of microglial cell migration.	got7fsn_ti							nc	2015-04-13T09:06:57Z						biological_process											owl:Class	
GO:0003378	biolink:NamedThing	obsolete regulation of inflammatory response by sphingosine-1-phosphate signaling pathway	OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response.	got7fsn_ti	regulation of inflammatory response by sphingolipid signalling pathway|regulation of inflammatory response by sphingolipid signaling pathway				The reason for obsoletion is that this term represents a GO-CAM model.		dph	2009-12-09T06:38:06Z		True				biological_process											owl:Class	
GO:0003704	biolink:NamedThing	obsolete specific RNA polymerase II transcription factor activity	OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II.	got7fsn_ti	specific RNA polymerase II transcription factor activity				This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006366|GO:0000981				True				molecular_function											owl:Class	
GO:2001317	biolink:NamedThing	kojic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of kojic acid.	got7fsn_ti	kojic acid biosynthesis|kojic acid formation|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|kojic acid synthesis|C6H6O4 synthesis|C6H6O4 anabolism|C6H6O4 formation|C6H6O4 biosynthetic process|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|C6H6O4 biosynthesis|kojic acid anabolism|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis						bf	2012-04-18T09:22:46Z						biological_process											owl:Class	
GO:1900128	biolink:NamedThing	regulation of G-protein activated inward rectifier potassium channel activity	Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.	got7fsn_ti	regulation of G protein enhanced inward rectifier potassium channel activity|regulation of G-protein enhanced inward rectifier potassium channel activity|regulation of G protein activated inward rectifier potassium channel activity|regulation of G-protein-activated inward rectifier potassium channel activity|regulation of G-protein-enhanced inward rectifier potassium channel activity						bf	2012-02-23T03:12:53Z						biological_process											owl:Class	
GO:0072268	biolink:NamedThing	pattern specification involved in metanephros development	Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.	got7fsn_ti	metanephros pattern formation|metanephros pattern specification|pattern formation involved in metanephros development						mah	2010-03-30T03:06:30Z						biological_process											owl:Class	
GO:0030702	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036495	biolink:NamedThing	negative regulation of translation initiation in response to endoplasmic reticulum stress	Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.	got7fsn_ti	negative regulation of translation initiation in response to ER stress						bf	2015-02-05T10:13:38Z						biological_process											owl:Class	
GO:1900657	biolink:NamedThing	positive regulation of diorcinol biosynthetic process	Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process.	got7fsn_ti	positive regulation of diorcinol biosynthesis|upregulation of diorcinol formation|up-regulation of diorcinol anabolism|up regulation of diorcinol formation|upregulation of diorcinol anabolism|up-regulation of diorcinol formation|up regulation of diorcinol biosynthesis|activation of diorcinol biosynthetic process|activation of diorcinol biosynthesis|activation of diorcinol formation|upregulation of diorcinol synthesis|up regulation of diorcinol biosynthetic process|up regulation of diorcinol anabolism|activation of diorcinol synthesis|positive regulation of diorcinol synthesis|activation of diorcinol anabolism|upregulation of diorcinol biosynthetic process|up-regulation of diorcinol synthesis|up regulation of diorcinol synthesis|positive regulation of diorcinol anabolism|upregulation of diorcinol biosynthesis|positive regulation of diorcinol formation|up-regulation of diorcinol biosynthetic process|up-regulation of diorcinol biosynthesis						di	2012-05-22T04:09:08Z						biological_process											owl:Class	
GO:0045101	biolink:NamedThing	obsolete glial fibrillary acidic protein	OBSOLETE. Glial fibrillary acidic protein forms filaments in the glial cells that surround neurons and in astrocytes.	got7fsn_ti	glial fibrillary acidic protein|GFAP				This term was made obsolete because it represents a gene product.	GO:0045098				True				cellular_component											owl:Class	
GO:0052708	biolink:NamedThing	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process	The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.	got7fsn_ti	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolism|hercynine metabolism|histidine betaine metabolism|hercynine metabolic process|histidine betaine metabolic process						ai	2011-08-05T02:13:31Z						biological_process											owl:Class	
GO:0072748	biolink:NamedThing	cellular response to tacrolimus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus.	got7fsn_ti	cellular response to FK506|cellular response to tacrolimus hydrate						mah	2012-08-31T12:34:32Z						biological_process											owl:Class	
GO:0002643	biolink:NamedThing	regulation of tolerance induction	Any process that modulates the frequency, rate, or extent of tolerance induction.	got7fsn_ti														biological_process											owl:Class	
GO:1903748	biolink:NamedThing	negative regulation of establishment of protein localization to mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion.	got7fsn_ti	downregulation of establishment of protein localization in mitochondrion|down-regulation of establishment of protein localization in mitochondrion|negative regulation of establishment of protein localisation to mitochondrion|down-regulation of establishment of protein localization to mitochondrion|down regulation of establishment of protein localization in mitochondrion|inhibition of establishment of protein localisation to mitochondrion|downregulation of establishment of protein localisation to mitochondrion|negative regulation of establishment of protein localization in mitochondrion|inhibition of establishment of protein localization in mitochondrion|downregulation of establishment of protein localization to mitochondrion|down regulation of establishment of protein localisation to mitochondrion|down regulation of establishment of protein localization to mitochondrion|inhibition of establishment of protein localization to mitochondrion|down-regulation of establishment of protein localisation to mitochondrion						krc	2014-12-12T22:18:18Z						biological_process											owl:Class	
GO:0006079	biolink:NamedThing	(1->6)-beta-D-glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans.	got7fsn_ti	1,6-beta-D-glucan catabolism|beta-1,6 glucan catabolic process|beta-1,6 glucan breakdown|1,6-beta-D-glucan breakdown|1,6-beta-D-glucan degradation|beta-1,6 glucan degradation|1,6-beta-D-glucan catabolic process|beta-1,6 glucan catabolism													biological_process											owl:Class	
GO:1904557	biolink:NamedThing	L-alanine transmembrane transport	The directed movement of L-alanine across a membrane.	got7fsn_ti							pr	2015-08-14T14:21:29Z						biological_process											owl:Class	
CHEBI:77135	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018330	biolink:NamedThing	obsolete enzyme active site formation via N6-(phospho-5'-guanosine)-L-lysine	OBSOLETE. The transient guanylylation of lysine to form N6-(phospho-5'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:6092377.	GO:0070568				True		RESID:AA0228		biological_process											owl:Class	
GO:1901792	biolink:NamedThing	3-(2,3-dihydroxyphenyl)propanoate biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate.	got7fsn_ti	3-(2,3-dihydroxyphenyl)propanoate formation|3-(2,3-dihydroxyphenyl)propanoate biosynthesis|3-(2,3-dihydroxyphenyl)propanoate anabolism|3-(2,3-dihydroxyphenyl)propanoate synthesis						yaf	2013-01-16T11:41:06Z						biological_process											owl:Class	
GO:0019309	biolink:NamedThing	mannose catabolic process	The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.	got7fsn_ti	mannose catabolism|mannose breakdown|mannose degradation											MetaCyc:MANNCAT-PWY		biological_process											owl:Class	
GO:0019387	biolink:NamedThing	methanogenesis, from methanol	The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol.	got7fsn_ti	methane biosynthesis from methanol|methane biosynthetic process from methanol											MetaCyc:METHFORM-PWY		biological_process											owl:Class	
GO:1900382	biolink:NamedThing	obsolete regulation of thiamine biosynthetic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of thiamine biosynthetic process.	got7fsn_ti	regulation of thiamine synthesis by regulation of transcription from RNA polymerase II promoter|regulation of thiamine anabolism by regulation of transcription from RNA polymerase II promoter|regulation of thiamine formation by regulation of transcription from RNA polymerase II promoter|regulation of thiamine biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of thiamin biosynthetic process by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-17T04:05:24Z		True				biological_process											owl:Class	
GO:0140500	biolink:NamedThing	regulation of reticulophagy	Any process that modulates the frequency, rate or extent of reticulophagy.	got7fsn_ti	regulation of autophagy of the endoplasmic reticulum|regulation of autophagy of the ER|regulation of endoplasmic reticulum autophagy|regulation of ER-phagy|regulation of ER autophagy|regulation of endoplasmic reticulum degradation|regulation of ER degradation	https://github.com/geneontology/go-ontology/issues/19860					pg	2020-08-10T12:01:22Z						biological_process											owl:Class	
GO:1904128	biolink:NamedThing	negative regulation of convergent extension involved in somitogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis.	got7fsn_ti	downregulation of convergent extension involved in somitogenesis|down regulation of convergent extension involved in somitogenesis|down-regulation of convergent extension involved in somitogenesis|inhibition of convergent extension involved in somitogenesis						dph	2015-04-10T21:13:10Z						biological_process											owl:Class	
GO:0050749	biolink:NamedThing	obsolete apolipoprotein E receptor binding	OBSOLETE. Interacting selectively with an apolipoprotein E receptor.	got7fsn_ti	apolipoprotein E receptor binding			GO:0070326	This term was made obsolete because no known receptor binds apolipoprotein E; instead, receptors bind holo-lipoprotein E (apolipoprotein E + bound lipid).					True				molecular_function											owl:Class	
GO:1904154	biolink:NamedThing	positive regulation of retrograde protein transport, ER to cytosol	Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.	got7fsn_ti	up-regulation of retrograde protein transport, endoplasmic reticulum to cytosol|positive regulation of protein retrotranslocation from ER|upregulation of retrograde protein transport, endoplasmic reticulum to cytosol|up regulation of retrograde protein transport, endoplasmic reticulum to cytosol|activation of retrograde protein transport, endoplasmic reticulum to cytosol|positive regulation of retrograde protein transport, endoplasmic reticulum to cytosol|activation of protein dislocation from ER|up-regulation of protein dislocation from ER|upregulation of protein dislocation from ER|up regulation of protein dislocation from ER|up-regulation of protein retrotranslocation from ER|up-regulation of retrograde protein transport, ER to cytosol|activation of retrograde protein transport, ER to cytosol|upregulation of retrograde protein transport, ER to cytosol|positive regulation of protein dislocation from ER|up regulation of retrograde protein transport, ER to cytosol						bf	2015-04-15T09:23:19Z						biological_process											owl:Class	
GO:0097223	biolink:NamedThing	obsolete sperm part	OBSOLETE. Any constituent part of a sperm, a mature male germ cell that develops from a spermatid.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	CL:0000019	pr	2012-01-25T01:19:35Z		True				cellular_component											owl:Class	
GO:0030192	biolink:NamedThing	obsolete Hsp70/Hsc70 protein regulator activity	OBSOLETE. Modulates the activity of chaperones of the Hsp70/Hsc70 class.	got7fsn_ti	Hsp70/Hsc70 protein regulator activity				This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70/Hsc70 protein activity'.	GO:0006457|GO:0051082|GO:0051787				True				molecular_function											owl:Class	
CHEBI:16064	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046068	biolink:NamedThing	cGMP metabolic process	The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.	got7fsn_ti	cGMP metabolism													biological_process											owl:Class	
GO:0007190	biolink:NamedThing	activation of adenylate cyclase activity	Any process that initiates the activity of the inactive enzyme adenylate cyclase.	got7fsn_ti	adenylate cyclase activator|adenylate cyclase activation|adenylyl cyclase activation													biological_process											owl:Class	
GO:0002500	biolink:NamedThing	proteolysis within lysosome associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.	got7fsn_ti	lysosomal proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0071849	biolink:NamedThing	obsolete G1 cell cycle arrest in response to nitrogen starvation	OBSOLETE. The process in which the cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20989			This term was obsoleted because it does not represent a specific process.		mah	2010-09-10T02:46:11Z		True				biological_process											owl:Class	
GO:0006199	biolink:NamedThing	obsolete ADP reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ADP reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051061				True				biological_process											owl:Class	
GO:1905680	biolink:NamedThing	regulation of innate immunity memory response	Any process that modulates the frequency, rate or extent of innate immunity memory response.	got7fsn_ti							tb	2016-11-11T22:25:21Z						biological_process											owl:Class	
GO:0070424	biolink:NamedThing	regulation of nucleotide-binding oligomerization domain containing signaling pathway	Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway.	got7fsn_ti	regulation of NOD signaling pathway|regulation of nucleotide-binding oligomerization domain containing signalling pathway													biological_process											owl:Class	
GO:2001277	biolink:NamedThing	negative regulation of leucine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process.	got7fsn_ti	negative regulation of leucine formation|negative regulation of leucine biosynthesis|negative regulation of leucine synthesis|negative regulation of leucine anabolism						mcc	2011-12-13T03:13:36Z						biological_process											owl:Class	
GO:1904590	biolink:NamedThing	negative regulation of protein import	Any process that stops, prevents or reduces the frequency, rate or extent of protein import.	got7fsn_ti	inhibition of protein import|down-regulation of protein uptake|negative regulation of protein uptake|inhibition of protein uptake|down-regulation of protein import|downregulation of protein import|down regulation of protein import|downregulation of protein uptake|down regulation of protein uptake						sl	2015-08-20T21:26:36Z						biological_process											owl:Class	
GO:0009398	biolink:NamedThing	FMN biosynthetic process	The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.	got7fsn_ti	FMN synthesis|FMN anabolism|FMN formation|FMN biosynthesis													biological_process											owl:Class	
GO:0016016	biolink:NamedThing	obsolete short-wave-sensitive opsin	OBSOLETE. An opsin with maximal absorption between 400 and 500 nm.	got7fsn_ti	short-wave-sensitive opsin				This term was made obsolete because it refers to a class of proteins.	GO:0009881|GO:0046876|GO:0007603|GO:0009588|GO:0016021|GO:0016918				True				molecular_function											owl:Class	
GO:1902933	biolink:NamedThing	isopentenol metabolic process	The chemical reactions and pathways involving isopentenol.	got7fsn_ti	isopentenol metabolism						tt	2014-04-24T16:51:35Z						biological_process											owl:Class	
GO:1990555	biolink:NamedThing	mitochondrial oxaloacetate transmembrane transport	The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:45:37Z						biological_process											owl:Class	
GO:0001943	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901559	biolink:NamedThing	response to ribavirin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus.	got7fsn_ti							hp	2012-11-02T09:46:28Z						biological_process											owl:Class	
GO:1903345	biolink:NamedThing	negative regulation of protein polyglycylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation.	got7fsn_ti	downregulation of protein polyglycylation|down regulation of protein polyglycylation|inhibition of protein polyglycylation|down-regulation of protein polyglycylation						sart	2014-08-19T09:32:16Z						biological_process											owl:Class	
GO:1900628	biolink:NamedThing	positive regulation of arugosin biosynthetic process	Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process.	got7fsn_ti	up-regulation of arugosin biosynthetic process|up-regulation of arugosin anabolism|upregulation of arugosin biosynthetic process|up-regulation of arugosin synthesis|up regulation of arugosin formation|up regulation of arugosin synthesis|up regulation of arugosin biosynthesis|positive regulation of arugosin biosynthesis|positive regulation of arugosin synthesis|upregulation of arugosin formation|upregulation of arugosin anabolism|activation of arugosin formation|activation of arugosin anabolism|up regulation of arugosin biosynthetic process|activation of arugosin synthesis|activation of arugosin biosynthesis|activation of arugosin biosynthetic process|upregulation of arugosin biosynthesis|up-regulation of arugosin biosynthesis|positive regulation of arugosin formation|up regulation of arugosin anabolism|up-regulation of arugosin formation|upregulation of arugosin synthesis|positive regulation of arugosin anabolism						di	2012-05-21T05:48:11Z						biological_process											owl:Class	
GO:0016065	biolink:NamedThing	obsolete humoral defense mechanism (sensu Protostomia)	OBSOLETE. The specific immune response mediated by antibodies. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).	got7fsn_ti	humoral defence mechanism (sensu Protostomia)|humoral defense mechanism (sensu Protostomia)				This term was made obsolete because antibodies are not found in the taxon Protostomia.					True				biological_process											owl:Class	
GO:0090035	biolink:NamedThing	positive regulation of chaperone-mediated protein complex assembly	Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.	got7fsn_ti							tb	2009-08-03T11:15:25Z						biological_process											owl:Class	
GO:0016104	biolink:NamedThing	triterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.	got7fsn_ti	triterpenoid formation|triterpene biosynthesis|triterpenoid anabolism|triterpenoid biosynthesis|triterpene biosynthetic process|triterpenoid synthesis													biological_process											owl:Class	
GO:0006653	biolink:NamedThing	1,2-diacyl-sn-glycero-3-phosphocholine metabolic process	The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin.	got7fsn_ti	lecithin metabolic process|1,2-diacyl-sn-glycero-3-phosphocholine metabolism													biological_process											owl:Class	
GO:0046341	biolink:NamedThing	CDP-diacylglycerol metabolic process	The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis.	got7fsn_ti	CDP-diacylglycerol metabolism													biological_process											owl:Class	
GO:0072463	biolink:NamedThing	obsolete detection of stimulus involved in meiotic spindle assembly checkpoint	OBSOLETE. The series of events in which information about whether spindle is correctly assembled and chromosomes are attached to the spindle is received and converted into a molecular signal, contributing to a meiotic spindle assembly checkpoint.	got7fsn_ti	meiotic spindle assembly checkpoint sensor process|sensing involved in meiotic spindle assembly checkpoint|meiotic spindle assembly checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:37:41Z		True				biological_process											owl:Class	
GO:0009662	biolink:NamedThing	etioplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.	got7fsn_ti	etioplast organisation|etioplast organization and biogenesis													biological_process											owl:Class	
GO:1902863	biolink:NamedThing	regulation of embryonic camera-type eye development	Any process that modulates the frequency, rate or extent of embryonic camera-type eye development.	got7fsn_ti	regulation of embryonic eye development						mr	2014-04-03T15:24:00Z						biological_process											owl:Class	
GO:0002596	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.	got7fsn_ti	downregulation of antigen processing and presentation of peptide antigen via MHC class Ib|down regulation of antigen processing and presentation of peptide antigen via MHC class Ib|down-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|inhibition of antigen processing and presentation of peptide antigen via MHC class Ib|negative regulation of peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:1902759	biolink:NamedThing	Mo(VI)-molybdopterin cytosine dinucleotide metabolic process	The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide.	got7fsn_ti	Mo(VI)-molybdopterin cytosine dinucleotide metabolism						dph	2014-03-06T14:00:31Z						biological_process											owl:Class	
GO:0110139	biolink:NamedThing	negative regulation of imaginal disc-derived leg joint morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.	got7fsn_ti							kmv	2019-02-12T15:40:09Z						biological_process											owl:Class	
GO:0090212	biolink:NamedThing	negative regulation of establishment of blood-brain barrier	Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.	got7fsn_ti	negative regulation of establishment of BBB						tb	2009-12-23T12:15:53Z						biological_process											owl:Class	
GO:0015487	biolink:NamedThing	melibiose:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in).	got7fsn_ti	melibiose permease activity|melibiose:monovalent cation symporter activity													molecular_function											owl:Class	
GO:1904275	biolink:NamedThing	tricellular tight junction disassembly	The disaggregation of a tricellular tight junction into its constituent components.	got7fsn_ti							mr	2015-05-29T16:31:06Z						biological_process											owl:Class	
GO:1905161	biolink:NamedThing	protein localization to phagocytic vesicle	A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle.	got7fsn_ti	protein localisation in phagocytic vesicle|protein localisation to phagocytic vesicle|protein localisation to phagosome|protein recruitment to phagosome|protein localization in phagocytic vesicle						bf	2016-04-25T15:05:13Z						biological_process											owl:Class	
GO:0052710	biolink:NamedThing	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process	The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.	got7fsn_ti	hercynine catabolism|histidine betaine catabolic process|hercynine catabolic process|hercynine breakdown|hercynine degradation|histidine betaine catabolism|histidine betaine degradation|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine degradation|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism|histidine betaine breakdown|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine breakdown						ai	2011-08-05T02:22:54Z						biological_process											owl:Class	
GO:1901032	biolink:NamedThing	negative regulation of response to reactive oxygen species	Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species.	got7fsn_ti	downregulation of response to AOS|downregulation of response to ROI|downregulation of response to active oxygen species|inhibition of response to active oxygen species|down regulation of response to AOS|inhibition of response to reactive oxygen species|down-regulation of response to reactive oxygen species|down regulation of response to reactive oxygen species|down-regulation of response to ROI|down-regulation of response to ROS|inhibition of response to AOS|negative regulation of response to ROI|negative regulation of response to reactive oxidative species|down regulation of response to active oxygen species|inhibition of response to reactive oxygen intermediate|inhibition of response to reactive oxidative species|down-regulation of response to active oxygen species|down-regulation of response to reactive oxidative species|downregulation of response to reactive oxidative species|negative regulation of response to AOS|down-regulation of response to reactive oxygen intermediate|negative regulation of response to ROS|inhibition of response to ROI|downregulation of response to ROS|negative regulation of response to reactive oxygen intermediate|down regulation of response to ROI|down regulation of response to reactive oxygen intermediate|downregulation of response to reactive oxygen intermediate|inhibition of response to ROS|down-regulation of response to AOS|negative regulation of response to active oxygen species|down regulation of response to reactive oxidative species|downregulation of response to reactive oxygen species|down regulation of response to ROS						kmv	2012-06-20T07:47:28Z						biological_process											owl:Class	
GO:0001988	biolink:NamedThing	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.	got7fsn_ti	positive regulation of heart contraction rate in baroreceptor response to decreased blood pressure|upregulation of heart contraction rate in baroreceptor response to decreased blood pressure|up regulation of heart contraction rate in baroreceptor response to decreased blood pressure|up-regulation of heart contraction rate in baroreceptor response to decreased blood pressure|stimulation of heart contraction rate in baroreceptor response to decreased blood pressure|activation of heart contraction rate in baroreceptor response to decreased blood pressure|positive regulation of cardiac contraction rate in baroreceptor response to decreased blood pressure|positive control of heart contraction rate in baroreceptor response to decreased blood pressure													biological_process											owl:Class	
GO:2001018	biolink:NamedThing	negative regulation of retrograde axon cargo transport	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.	got7fsn_ti	negative regulation of retrograde axonal transport						kmv	2011-08-11T09:44:46Z						biological_process											owl:Class	
GO:2000487	biolink:NamedThing	positive regulation of glutamine transport	Any process that activates or increases the frequency, rate or extent of glutamine transport.	got7fsn_ti	positive regulation of L-glutamine transport						bf	2011-03-11T09:33:39Z						biological_process											owl:Class	
GO:0048602	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048819	biolink:NamedThing	regulation of hair follicle maturation	Any process that modulates the frequency, rate or extent of hair follicle maturation.	got7fsn_ti														biological_process											owl:Class	
GO:1901554	biolink:NamedThing	response to paracetamol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.	got7fsn_ti	response to acetaminophen						hp	2012-11-02T09:43:23Z						biological_process											owl:Class	
GO:1900356	biolink:NamedThing	positive regulation of methanofuran metabolic process	Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process.	got7fsn_ti	up-regulation of methanofuran metabolic process|up-regulation of methanofuran metabolism|activation of methanofuran metabolic process|upregulation of methanofuran metabolism|upregulation of methanofuran metabolic process|up regulation of methanofuran metabolic process|up regulation of methanofuran metabolism|activation of methanofuran metabolism|positive regulation of methanofuran metabolism						tt	2012-04-06T02:16:01Z						biological_process											owl:Class	
GO:2000283	biolink:NamedThing	negative regulation of cellular amino acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process.	got7fsn_ti	negative regulation of cellular amino acid biosynthesis|negative regulation of cellular amino acid synthesis|negative regulation of amino acid biosynthetic process|negative regulation of cellular amino acid anabolism|negative regulation of cellular amino acid formation						vw	2010-12-10T11:54:23Z						biological_process											owl:Class	
GO:1900436	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.	got7fsn_ti	upregulation of filamentous growth of a population of unicellular organisms in response to starvation|up-regulation of filamentous growth of a population of unicellular organisms in response to starvation|up regulation of filamentous growth of a population of unicellular organisms in response to starvation|activation of filamentous growth of a population of unicellular organisms in response to starvation						di	2012-04-25T05:55:05Z						biological_process											owl:Class	
GO:1903070	biolink:NamedThing	negative regulation of ER-associated ubiquitin-dependent protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.	got7fsn_ti	down-regulation of endoplasmic reticulum-associated protein catabolic process|down-regulation of ERAD|down regulation of ER-associated protein catabolic process|down-regulation of ER-associated ubiquitin-dependent protein catabolic process|downregulation of ERAD|downregulation of endoplasmic reticulum-associated protein catabolic process|inhibition of endoplasmic reticulum-associated protein catabolism|inhibition of ER-associated protein catabolic process|down-regulation of ER-associated protein catabolism|downregulation of ER-associated protein breakdown|down regulation of ER-associated protein degradation|down regulation of ER-associated ubiquitin-dependent protein catabolic process|negative regulation of endoplasmic reticulum-associated protein catabolic process|negative regulation of ERAD|inhibition of ER-associated protein degradation|downregulation of ER-associated protein degradation|inhibition of ERAD|downregulation of ER-associated protein catabolism|downregulation of ER-associated ubiquitin-dependent protein catabolic process|down-regulation of ER-associated protein catabolic process|down regulation of ERAD|down-regulation of endoplasmic reticulum-associated protein catabolism|negative regulation of ER-associated protein catabolic process|down regulation of endoplasmic reticulum-associated protein catabolism|down regulation of endoplasmic reticulum-associated protein catabolic process|negative regulation of ER-associated protein degradation|negative regulation of ER-associated protein breakdown|down regulation of ER-associated protein catabolism|down regulation of ER-associated protein breakdown|down-regulation of ER-associated protein breakdown|downregulation of ER-associated protein catabolic process|downregulation of endoplasmic reticulum-associated protein catabolism|negative regulation of endoplasmic reticulum-associated protein catabolism|inhibition of ER-associated protein breakdown|negative regulation of ER-associated protein catabolism|inhibition of ER-associated protein catabolism|inhibition of ER-associated ubiquitin-dependent protein catabolic process|inhibition of endoplasmic reticulum-associated protein catabolic process|down-regulation of ER-associated protein degradation						rph	2014-05-28T17:53:53Z						biological_process											owl:Class	
GO:0052206	biolink:NamedThing	obsolete modification of morphology or physiology of other organism via protein secreted by type II secretion system involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type II secretion system in the first organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modification of morphology or physiology of other organism via protein secreted by type II secretion system during symbiotic interaction				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0072753	biolink:NamedThing	cellular response to glutathione	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.	got7fsn_ti							mah	2012-09-25T12:27:39Z						biological_process											owl:Class	
GO:0070351	biolink:NamedThing	negative regulation of white fat cell proliferation	Any process that stops or decreases the rate or extent of white fat cell proliferation.	got7fsn_ti	down regulation of white fat cell proliferation|down-regulation of white fat cell proliferation|inhibition of white fat cell proliferation|downregulation of white fat cell proliferation|negative regulation of white adipose cell proliferation|negative regulation of white adipocyte proliferation													biological_process											owl:Class	
GO:1900499	biolink:NamedThing	positive regulation of butyryl-CoA catabolic process to butanol	Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol.	got7fsn_ti	activation of butyryl-CoA catabolic process to butanol|upregulation of butyryl-CoA catabolism to butanol|up regulation of butyryl-CoA catabolic process to butanol|up-regulation of butyryl-CoA catabolic process to butanol|up regulation of butyryl-CoA catabolism to butanol|activation of butyryl-CoA catabolism to butanol|up-regulation of butyryl-CoA catabolism to butanol|positive regulation of butyryl-CoA catabolism to butanol|upregulation of butyryl-CoA catabolic process to butanol						tt	2012-05-02T03:53:40Z						biological_process											owl:Class	
GO:0009980	biolink:NamedThing	obsolete glutamate carboxypeptidase activity	OBSOLETE. Catalysis of the release of C-terminal glutamate residues from a wide range of N-acylating groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups.	got7fsn_ti	glutamyl carboxypeptidase activity|carboxypeptidase G activity|N-pteroyl-L-glutamate hydrolase activity|carboxypeptidase G1 activity|carboxypeptidase G2 activity|glutamate carboxypeptidase activity			GO:0004180	This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.					True				molecular_function											owl:Class	
GO:0033311	biolink:NamedThing	chlorophyll a biosynthetic process via phytyl diphosphate	The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate.	got7fsn_ti	chlorophyll a anabolism via phytyl diphosphate|chlorophyll a biosynthetic process via phytyl-PP|chlorophyll a formation via phytyl chlorophyll a formation via phytyl-PP|chlorophyll a synthesis via phytyl diphosphate|chlorophyll a biosynthesis via phytyl diphosphate											MetaCyc:PWY-5086		biological_process											owl:Class	
GO:0075296	biolink:NamedThing	positive regulation of ascospore formation	Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.	got7fsn_ti														biological_process											owl:Class	
GO:1904928	biolink:NamedThing	coreceptor activity involved in canonical Wnt signaling pathway	Any coreceptor activity that is involved in a canonical Wnt signaling pathway.	got7fsn_ti	coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor activity involved in canonical Wnt-activated signaling pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor activity involved in frizzled-1 receptor signaling pathway|coreceptor activity involved in Wnt receptor signaling pathway via beta-catenin|Wnt co-receptor, canonical pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt-activated signaling pathway|coreceptor activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor, soluble ligand activity involved in frizzled-1 receptor signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt-activated signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt receptor signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor, insoluble ligand activity involved in frizzled-1 receptor signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt receptor signaling pathway|coreceptor, soluble ligand activity involved in canonical Wnt signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt signaling pathway|coreceptor activity involved in canonical Wnt receptor signaling pathway|Wnt co-receptor activity, canonical signaling						bf	2016-01-28T15:14:46Z						molecular_function											owl:Class	
GO:0061871	biolink:NamedThing	negative regulation of hepatic stellate cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.	got7fsn_ti							dph	2017-05-01T13:20:51Z						biological_process											owl:Class	
GO:0002265	biolink:NamedThing	astrocyte activation involved in immune response	A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	astrocyte activation during immune response													biological_process											owl:Class	
GO:0090095	biolink:NamedThing	regulation of metanephric cap mesenchymal cell proliferation	Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.	got7fsn_ti							tb	2009-11-13T10:40:32Z						biological_process											owl:Class	
GO:0008149	biolink:NamedThing	obsolete para-aminobenzoic acid (PABA) synthase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	para-aminobenzoic acid (PABA) synthase				This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered.	GO:0046820|GO:0008696				True				molecular_function											owl:Class	
GO:0098952	biolink:NamedThing	intrinsic component of spine apparatus membrane	The component of the spine apparatus membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to spine apparatus membrane													cellular_component											owl:Class	
GO:2001065	biolink:NamedThing	mannan binding	Binding to mannan.	got7fsn_ti	mannoglycan binding						jl	2011-09-14T10:49:45Z						molecular_function											owl:Class	
GO:2000304	biolink:NamedThing	positive regulation of ceramide biosynthetic process	Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process.	got7fsn_ti	positive regulation of ceramide synthesis|positive regulation of ceramide biosynthesis|positive regulation of ceramide anabolism|positive regulation of ceramide formation						dph	2011-01-04T02:37:32Z						biological_process											owl:Class	
GO:2000839	biolink:NamedThing	positive regulation of androstenedione secretion	Any process that activates or increases the frequency, rate or extent of androstenedione secretion.	got7fsn_ti	positive regulation of androst-4-ene-3,17-dione secretion						bf	2011-07-26T08:40:42Z						biological_process											owl:Class	
GO:0002135	biolink:NamedThing	CTP binding	Binding to CTP, cytidine 5'-triphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0002733	biolink:NamedThing	regulation of myeloid dendritic cell cytokine production	Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.	got7fsn_ti														biological_process											owl:Class	
GO:0016124	biolink:NamedThing	xanthophyll catabolic process	The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.	got7fsn_ti	xanthophyll breakdown|xanthophyll degradation|xanthophyll catabolism													biological_process											owl:Class	
GO:0045155	biolink:NamedThing	obsolete electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity	OBSOLETE. Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex.	got7fsn_ti	cytochrome|cytochrome c				This term was obsoleted because it was not clearly defined, it has no corresponding EC or RHEA.					True				molecular_function											owl:Class	
GO:0030972	biolink:NamedThing	obsolete cleavage of cytosolic proteins involved in execution phase of apoptosis	OBSOLETE. The proteolytic degradation of proteins in the cytosol that contributes to apoptosis.	got7fsn_ti	cleavage of cytosolic proteins involved in apoptosis|apoptotic cleavage of cytosolic proteins|cleavage of cytosolic proteins involved in execution phase of apoptosis				This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'.	GO:0097200				True				biological_process											owl:Class	
GO:1901557	biolink:NamedThing	response to fenofibrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.	got7fsn_ti							hp	2012-11-02T09:46:20Z						biological_process											owl:Class	
GO:0061960	biolink:NamedThing	regulation of heme oxygenase activity	Any process that modulates the frequency, or rate of heme oxygenase activity.	got7fsn_ti							dph	2018-01-22T20:24:06Z						biological_process											owl:Class	
GO:0036444	biolink:NamedThing	calcium import into the mitochondrion	A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti	calcium ion transmembrane import into mitochondrion|mitochondrial calcium uptake|mitochondrial calcium ion import|calcium ion import into mitochondrion						bf	2013-10-28T09:32:39Z						biological_process											owl:Class	
GO:2000608	biolink:NamedThing	positive regulation of cell proliferation involved in mesonephros development	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development.	got7fsn_ti							yaf	2011-04-18T08:42:25Z						biological_process											owl:Class	
GO:1904148	biolink:NamedThing	cellular response to nonylphenol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.	got7fsn_ti							sl	2015-04-14T17:01:50Z						biological_process											owl:Class	
GO:1900315	biolink:NamedThing	regulation of maltopentaose transport	Any process that modulates the frequency, rate or extent of maltopentaose transport.	got7fsn_ti							tt	2012-04-05T07:59:47Z						biological_process											owl:Class	
GO:1902803	biolink:NamedThing	regulation of synaptic vesicle transport	Any process that modulates the frequency, rate or extent of synaptic vesicle transport.	got7fsn_ti	regulation of synaptic vesicle fusion|regulation of synaptic vesicle fission						kmv	2014-03-25T14:56:34Z						biological_process											owl:Class	
GO:0032124	biolink:NamedThing	macronucleus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus.	got7fsn_ti	macronuclear organization and biogenesis|macronucleus organisation|macronuclear organization													biological_process											owl:Class	
GO:0060588	biolink:NamedThing	negative regulation of lipoprotein lipid oxidation	Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.	got7fsn_ti							dph	2009-05-08T02:30:49Z						biological_process											owl:Class	
GO:0052327	biolink:NamedThing	obsolete interaction with symbiont via protein secreted by type II secretion system	OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type II secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with symbiont via protein secreted by type II secretion system				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0018128	biolink:NamedThing	obsolete peptidyl-serine cyclase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peptidyl-serine cyclase activity				This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists.					True		EC:4.2.1.-		molecular_function											owl:Class	
GO:0006601	biolink:NamedThing	creatine biosynthetic process	The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.	got7fsn_ti	creatine synthesis|creatine biosynthesis|creatine formation|creatine anabolism													biological_process											owl:Class	
GO:0009205	biolink:NamedThing	purine ribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine ribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0097295	biolink:NamedThing	morphine biosynthetic process	The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.	got7fsn_ti	morphine biosynthesis|morphine synthesis|morphine formation|morphine anabolism						pr	2012-05-02T09:51:19Z						biological_process											owl:Class	
GO:0016637	biolink:NamedThing	obsolete oxidoreductase activity, acting on the CH-CH group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or related compound, a cytochrome, an iron-sulfur protein, NAD, NADP or oxygen.	got7fsn_ti	oxidoreductase activity, acting on the CH-CH group of donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016627				True				molecular_function											owl:Class	
GO:0045347	biolink:NamedThing	negative regulation of MHC class II biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.	got7fsn_ti	negative regulation of MHC class II synthesis|inhibition of MHC class II biosynthetic process|downregulation of MHC class II biosynthetic process|down regulation of MHC class II biosynthetic process|negative regulation of MHC class II anabolism|negative regulation of major histocompatibility complex class II biosynthetic process|down-regulation of MHC class II biosynthetic process|negative regulation of major histocompatibility complex class II biosynthesis|negative regulation of MHC class II formation|negative regulation of MHC class II biosynthesis													biological_process											owl:Class	
CHEBI:77805	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000016	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032073	biolink:NamedThing	negative regulation of restriction endodeoxyribonuclease activity	Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.	got7fsn_ti	restriction enzyme inhibitor|downregulation of restriction endodeoxyribonuclease activity|restriction endodeoxyribonuclease inhibitor|restriction alleviation|down-regulation of restriction endodeoxyribonuclease activity|inhibition of restriction endodeoxyribonuclease activity|down regulation of restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0051000	biolink:NamedThing	positive regulation of nitric-oxide synthase activity	Any process that activates or increases the activity of the enzyme nitric-oxide synthase.	got7fsn_ti	upregulation of nitric-oxide synthase activity|up-regulation of nitric-oxide synthase activity|stimulation of nitric-oxide synthase activity|nitric-oxide synthase activator|up regulation of nitric-oxide synthase activity|activation of nitric-oxide synthase activity|positive regulation of NOS activity|NOS activator													biological_process											owl:Class	
GO:1904160	biolink:NamedThing	protein localization to chloroplast starch grain	A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain.	got7fsn_ti	protein localisation in chloroplast starch grain|protein localisation to chloroplast starch grain|protein localization in chloroplast starch grain						lr	2015-04-20T18:06:17Z						biological_process											owl:Class	
GO:1901357	biolink:NamedThing	beta-D-galactofuranose catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose.	got7fsn_ti	beta-D-galactofuranose catabolism|beta-D-galactofuranose breakdown|beta-D-galactofuranose degradation						di	2012-09-13T22:19:30Z						biological_process											owl:Class	
GO:1901090	biolink:NamedThing	regulation of protein tetramerization	Any process that modulates the frequency, rate or extent of protein tetramerization.	got7fsn_ti	regulation of protein tetramer assembly|regulation of protein tetramer formation|regulation of protein tetramer biosynthesis|regulation of protein tetramer biosynthetic process						pm	2012-07-06T12:51:00Z						biological_process											owl:Class	
GO:0045782	biolink:NamedThing	positive regulation of cell budding	Any process that activates or increases the frequency, rate or extent of cell budding.	got7fsn_ti	up regulation of cell budding|positive regulation of budding|activation of cell budding|upregulation of cell budding|stimulation of cell budding|up-regulation of cell budding													biological_process											owl:Class	
GO:0008077	biolink:NamedThing	obsolete Hsp70/Hsp90 organizing protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Hsp70/Hsp90 organising protein activity|Hsp70/Hsp90 organizing protein activity				This term was made obsolete because it represents a specific gene product rather than a molecular function.	GO:0030674				True				molecular_function											owl:Class	
UBERON:0001876	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016915	biolink:NamedThing	obsolete activin	OBSOLETE. A nonsteroidal regulator, composed of two covalently linked beta subunits, that is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.	got7fsn_ti	activin				This term was made obsolete because it represents a gene product.	GO:0005160|GO:0046881				True				molecular_function											owl:Class	
GO:0038078	biolink:NamedThing	obsolete MAP kinase phosphatase activity involved in regulation of innate immune response	OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to an innate immune response.	got7fsn_ti	MAPK phosphatase activity involved in regulation of innate immune response	https://github.com/geneontology/go-ontology/issues/21552			This term was obsoleted because it represents a biological process within the molecular function branch.		bf	2012-01-26T02:35:52Z		True				molecular_function											owl:Class	
GO:0043882	biolink:NamedThing	malate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).	got7fsn_ti	malate-sodium symporter activity|malate Na(+) symporter activity|malate:Na+ symporter activity|Na+:malate symporter activity|malate/sodium symporter activity|Na(+)-malate symporter activity|sodium:malate symporter activity|sodium-dependent malate transporter|malate/sodium cotransporter activity|malate:sodium cotransporter activity|sodium/malate symporter activity													molecular_function											owl:Class	
GO:0043189	biolink:NamedThing	H4/H2A histone acetyltransferase complex	A multisubunit complex that catalyzes the acetylation of histones H4 and H2A.	got7fsn_ti	H4/H2A HAT complex													cellular_component											owl:Class	
GO:1904576	biolink:NamedThing	response to tunicamycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus.	got7fsn_ti							sl	2015-08-19T18:01:52Z						biological_process											owl:Class	
GO:0090455	biolink:NamedThing	ornithine transmembrane import into vacuole	The directed movement of ornithine into the vacuole across the vacuolar membrane.	got7fsn_ti	vacuolar ornithine import						tb	2012-09-24T14:12:46Z						biological_process											owl:Class	
GO:0014008	biolink:NamedThing	positive regulation of microglia differentiation	Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.	got7fsn_ti	upregulation of microglia differentiation|up regulation of microglia differentiation|activation of microglia differentiation|stimulation of microglia differentiation|positive regulation of microglial cell differentiation|up-regulation of microglia differentiation													biological_process											owl:Class	
GO:1904901	biolink:NamedThing	positive regulation of myosin II filament organization	Any process that activates or increases the frequency, rate or extent of myosin II filament organization.	got7fsn_ti	up-regulation of myosin II filament assembly or disassembly|up regulation of myosin II polymerization or depolymerization|up regulation of myosin II filament assembly or disassembly|positive regulation of myosin II polymerization or depolymerization|activation of myosin II filament assembly or disassembly|positive regulation of myosin II filament organisation|upregulation of myosin II polymerization or depolymerization|up-regulation of myosin II filament organization|up regulation of myosin II filament organisation|upregulation of myosin II filament organization|up-regulation of myosin II filament organisation|activation of myosin II filament organization|up regulation of myosin II filament organization|activation of myosin II filament organisation|activation of myosin II polymerization or depolymerization|upregulation of myosin II filament organisation|upregulation of myosin II filament assembly or disassembly|positive regulation of myosin II filament assembly or disassembly|up-regulation of myosin II polymerization or depolymerization						mec	2016-01-15T09:05:02Z						biological_process											owl:Class	
GO:0070884	biolink:NamedThing	regulation of calcineurin-NFAT signaling cascade	Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.	got7fsn_ti	regulation of calcineurin-NFAT signaling pathway|regulation of NFAT protein import into nucleus|NFAT protein import into nucleus|regulation of calcineurin-NFAT signalling cascade						mah	2009-08-26T03:25:30Z			GO:0051531|GO:0051532			biological_process											owl:Class	
GO:0071272	biolink:NamedThing	morphine metabolic process	The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.	got7fsn_ti	morphine metabolism						mah	2009-12-10T11:11:51Z				Wikipedia:Morphine		biological_process											owl:Class	
GO:1902481	biolink:NamedThing	gamma-tubulin complex assembly	The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex.	got7fsn_ti	gamma-tubulin complex formation						mah	2013-11-04T13:21:12Z						biological_process											owl:Class	
GO:0033332	biolink:NamedThing	ent-kaurene biosynthetic process	The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.	got7fsn_ti	ent-kaurene formation|ent-kaurene synthesis|ent-kaurene anabolism|ent-kaurene biosynthesis											MetaCyc:PWY-5032|MetaCyc:PWY-5035		biological_process											owl:Class	
GO:1905848	biolink:NamedThing	positive regulation of cellular response to oxidopamine	Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine.	got7fsn_ti	up regulation of cellular response to oxidopamine|up-regulation of cellular response to oxidopamine|upregulation of cellular response to oxidopamine|activation of cellular response to oxidopamine						rz	2017-01-19T10:47:04Z						biological_process											owl:Class	
GO:1904288	biolink:NamedThing	BAT3 complex binding	Binding to a BAT3 complex.	got7fsn_ti	BAG6-UBL4A-TRC35 complex binding|BAT3-TRC35-UBL4A complex binding|Bag6 complex binding						bf	2015-06-07T19:48:55Z						molecular_function											owl:Class	
GO:0045587	biolink:NamedThing	negative regulation of gamma-delta T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation.	got7fsn_ti	negative regulation of gamma-delta T lymphocyte differentiation|negative regulation of gamma-delta T cell development|downregulation of gamma-delta T cell differentiation|inhibition of gamma-delta T cell differentiation|negative regulation of gamma-delta T-cell differentiation|down-regulation of gamma-delta T cell differentiation|negative regulation of gamma-delta T-lymphocyte differentiation|down regulation of gamma-delta T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0061649	biolink:NamedThing	ubiquitin modification-dependent histone binding	Binding to a histone protein in which a residue has been modified by ubiquitination. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.	got7fsn_ti	ubiquitinated histone binding						dph	2014-11-04T10:21:04Z						molecular_function											owl:Class	
GO:0075305	biolink:NamedThing	obsolete modulation of growth or development of symbiont on or near host	OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	got7fsn_ti	modulation of growth or development of symbiont on or near host|modulation of growth or development of symbiont on or near host surface				This term was made obsolete because it contained a conjunction (or).					True				biological_process											owl:Class	
GO:1900135	biolink:NamedThing	positive regulation of renin secretion into blood stream	Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream.	got7fsn_ti	up regulation of renin release into blood stream|up-regulation of renin release into blood stream|upregulation of renin release into blood stream|positive regulation of renin release into blood stream|up-regulation of renin secretion into blood stream|activation of renin secretion into blood stream|upregulation of renin secretion into blood stream|up regulation of renin secretion into blood stream|activation of renin release into blood stream						rph	2012-02-27T10:32:08Z						biological_process											owl:Class	
GO:0008439	biolink:NamedThing	obsolete monophenol monooxygenase activator activity	OBSOLETE. Increases the activity of the enzyme monophenol monooxygenase.	got7fsn_ti	monophenol monooxygenase activator activity|prophenol oxidase activator			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0072182	biolink:NamedThing	regulation of nephron tubule epithelial cell differentiation	Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation.	got7fsn_ti							mah	2010-02-26T02:45:09Z						biological_process											owl:Class	
GO:0046673	biolink:NamedThing	negative regulation of compound eye retinal cell programmed cell death	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.	got7fsn_ti	negative regulation of retina cell programmed cell death|down-regulation of retinal cell programmed cell death|downregulation of retinal cell programmed cell death|inhibition of retinal cell programmed cell death|down regulation of retinal cell programmed cell death|negative regulation of retinal cell programmed cell death													biological_process											owl:Class	
GO:0032871	biolink:NamedThing	regulation of karyogamy	Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.	got7fsn_ti														biological_process											owl:Class	
CHEBI:143079	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900836	biolink:NamedThing	positive regulation of emericellin biosynthetic process	Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process.	got7fsn_ti							di	2012-06-07T09:32:31Z						biological_process											owl:Class	
GO:1905506	biolink:NamedThing	gerontoplast stroma	Any plastid stroma that is part of a gerontoplast.	got7fsn_ti							tb	2016-09-27T20:01:34Z						cellular_component											owl:Class	
GO:0032877	biolink:NamedThing	positive regulation of DNA endoreduplication	Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.	got7fsn_ti	positive regulation of DNA endoreplication|activation of DNA endoreduplication|up regulation of DNA endoreduplication|stimulation of DNA endoreduplication|positive regulation of DNA re-duplication|up-regulation of DNA endoreduplication|upregulation of DNA endoreduplication													biological_process											owl:Class	
GO:2001172	biolink:NamedThing	positive regulation of glycolytic fermentation to ethanol	Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol.	got7fsn_ti	positive regulation of glucose fermentation to ethanol|positive regulation of ethanol fermentation						mcc	2011-10-27T02:39:09Z						biological_process											owl:Class	
GO:0009476	biolink:NamedThing	obsolete class IV cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	class IV cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:1900710	biolink:NamedThing	regulation of tensidol B biosynthetic process	Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process.	got7fsn_ti	regulation of tensidol B biosynthesis|regulation of tensidol B anabolism|regulation of tensidol B synthesis|regulation of tensidol B formation						di	2012-05-22T05:02:55Z						biological_process											owl:Class	
GO:0101017	biolink:NamedThing	regulation of mitotic DNA replication initiation from late origin	Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.	got7fsn_ti	regulation of late replication origin firing						mec							biological_process											owl:Class	
GO:0035835	biolink:NamedThing	indole alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.	got7fsn_ti	indole alkaloid biosynthesis|indole alkaloid synthesis|indole alkaloid anabolism|indole alkaloid formation						bf	2011-05-04T03:18:31Z						biological_process											owl:Class	
GO:1903191	biolink:NamedThing	glyoxal biosynthetic process	The chemical reactions and pathways resulting in the formation of glyoxal.	got7fsn_ti	glyoxal formation|glyoxal synthesis|glyoxal biosynthesis|glyoxal anabolism						bf	2014-07-15T10:11:57Z						biological_process											owl:Class	
GO:0140276	biolink:NamedThing	obsolete pericentric heterochromatin maintenance	OBSOLETE. Any heterochromatin maintenance that is involved in chromatin silencing at or near a centromere.	got7fsn_ti	heterochromatin maintenance involved in chromatin silencing at centromeric outer repeats|heterochromatin maintenance involved in chromatin silencing at pericentric region|heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region	https://github.com/geneontology/go-ontology/issues/19301			This term was obsoleted because it represents a phenotype.		bf	2013-08-21T10:13:39Z		True	GO:1902368			biological_process											owl:Class	
GO:0005804	biolink:NamedThing	obsolete secretory vesicle membrane	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	secretory vesicle membrane				This term was made obsolete because its parent was made obsolete.	GO:0030658|GO:0030667				True				cellular_component											owl:Class	
GO:0032913	biolink:NamedThing	negative regulation of transforming growth factor beta3 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.	got7fsn_ti	inhibition of transforming growth factor-beta3 production|down-regulation of transforming growth factor-beta3 production|negative regulation of TGFB3 production|downregulation of transforming growth factor-beta3 production|negative regulation of TGF-B3 production|down regulation of transforming growth factor-beta3 production|negative regulation of transforming growth factor-beta3 production													biological_process											owl:Class	
GO:0016681	biolink:NamedThing	obsolete oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome.	got7fsn_ti					This term was obsoleted because the EC it represented was obsoleted.					True		EC:1.10.2.-		molecular_function											owl:Class	
GO:1900186	biolink:NamedThing	negative regulation of clathrin-dependent endocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis.	got7fsn_ti	inhibition of clathrin-mediated endocytosis|negative regulation of clathrin-mediated endocytosis|down regulation of clathrin-dependent endocytosis|down regulation of clathrin-mediated endocytosis|down regulation of clathrin coated pit-dependent endocytosis|down-regulation of clathrin coated pit-dependent endocytosis|downregulation of clathrin-mediated endocytosis|down-regulation of clathrin-dependent endocytosis|negative regulation of clathrin-dependent endocytosis|downregulation of clathrin coated pit-dependent endocytosis|down-regulation of clathrin-mediated endocytosis|inhibition of clathrin-dependent endocytosis|negative regulation of clathrin coated pit-dependent endocytosis|downregulation of clathrin-dependent endocytosis|inhibition of clathrin coated pit-dependent endocytosis						hjd	2012-03-16T05:25:02Z						biological_process											owl:Class	
GO:1901465	biolink:NamedThing	positive regulation of tetrapyrrole biosynthetic process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process.	got7fsn_ti	up-regulation of tetrapyrrole biosynthetic process|activation of tetrapyrrole biosynthetic process|upregulation of tetrapyrrole biosynthetic process|positive regulation of tetrapyrrole synthesis|positive regulation of tetrapyrrole anabolism|upregulation of tetrapyrrole synthesis|positive regulation of tetrapyrrole biosynthesis|up-regulation of tetrapyrrole formation|positive regulation of tetrapyrrole formation|activation of tetrapyrrole biosynthesis|upregulation of tetrapyrrole formation|upregulation of tetrapyrrole anabolism|activation of tetrapyrrole anabolism|up regulation of tetrapyrrole biosynthetic process|upregulation of tetrapyrrole biosynthesis|up regulation of tetrapyrrole biosynthesis|up regulation of tetrapyrrole anabolism|activation of tetrapyrrole synthesis|up regulation of tetrapyrrole synthesis|up-regulation of tetrapyrrole anabolism|up-regulation of tetrapyrrole synthesis|activation of tetrapyrrole formation|up regulation of tetrapyrrole formation|up-regulation of tetrapyrrole biosynthesis						tt	2012-10-02T14:35:43Z						biological_process											owl:Class	
GO:0002842	biolink:NamedThing	positive regulation of T cell mediated immune response to tumor cell	Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell.	got7fsn_ti	positive regulation of T cell mediated immune response to tumour cell|positive regulation of T-lymphocyte mediated immune response to tumor cell|activation of T cell mediated immune response to tumor cell|up-regulation of T cell mediated immune response to tumor cell|stimulation of T cell mediated immune response to tumor cell|up regulation of T cell mediated immune response to tumor cell|positive regulation of T lymphocyte mediated immune response to tumor cell|upregulation of T cell mediated immune response to tumor cell|positive regulation of T-cell mediated immune response to tumor cell													biological_process											owl:Class	
GO:0052410	biolink:NamedThing	obsolete metabolism by host of symbiont cell wall chitin	OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1905018	biolink:NamedThing	regulation of methionine-tRNA ligase activity	Any process that modulates the frequency, rate or extent of methionine-tRNA ligase activity.	got7fsn_ti	regulation of methionyl-transfer RNA synthetase activity|regulation of methionyl-transfer ribonucleate synthetase activity|regulation of methionyl-transfer ribonucleic acid synthetase activity|regulation of L-methionine:tRNAMet ligase (AMP-forming)|regulation of methionine translase activity|regulation of methionyl-tRNA synthetase activity|regulation of MetRS activity						sl	2016-03-03T19:02:39Z						biological_process											owl:Class	
GO:1905302	biolink:NamedThing	negative regulation of macropinocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis.	got7fsn_ti	inhibition of macropinocytosis|down-regulation of macropinocytosis|downregulation of macropinocytosis|down regulation of macropinocytosis						pad	2016-07-04T14:16:41Z						biological_process											owl:Class	
GO:0006252	biolink:NamedThing	obsolete CTP reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	CTP reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051065				True				biological_process											owl:Class	
GO:0085007	biolink:NamedThing	obsolete interaction with host via secreted substance released from rhoptry	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the rhoptry, a large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was deprecated because it conflated the process in which a gene product is involved with the secreaton system by which it reaches its target.		jl	2010-02-10T03:02:08Z		True				biological_process											owl:Class	
GO:0120314	biolink:NamedThing	negative regulation of oocyte karyosome formation	Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21298					krc	2021-04-19T21:39:47Z						biological_process											owl:Class	
GO:0045890	biolink:NamedThing	obsolete regulation of transcription of homeotic gene (trithorax group)	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the trithorax group.	got7fsn_ti	regulation of transcription of homeotic gene (trithorax group)				This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0006357				True				biological_process											owl:Class	
GO:1901894	biolink:NamedThing	regulation of ATPase-coupled calcium transmembrane transporter activity	Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.	got7fsn_ti	regulation of calcium ABC transporter|regulation of calcium transporting ATPase activity|regulation of calcium-translocating P-type ATPase activity|regulation of plasma membrane Ca-ATPase|regulation of calcium-transporting ATPase activity|regulation of calcium pump|regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|regulation of calcium efflux ATPase|regulation of ATP phosphohydrolase (Ca2+-transporting)|regulation of Ca2+-pumping ATPase activity|regulation of Ca(2+)-transporting ATPase activity|regulation of sarcoplasmic reticulum ATPase|regulation of Ca2+-transporting ATPase activity						rl	2013-02-06T21:18:16Z						biological_process											owl:Class	
GO:1901943	biolink:NamedThing	(+)-epi-alpha-bisabolol biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.	got7fsn_ti	(+)-epi-alpha-bisabolol biosynthesis|(+)-epi-alpha-bisabolol anabolism|(+)-epi-alpha-bisabolol synthesis|(+)-epi-alpha-bisabolol formation						ms	2013-02-18T14:55:46Z						biological_process											owl:Class	
GO:0048476	biolink:NamedThing	Holliday junction resolvase complex	An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated.	got7fsn_ti	Mus81-Eme1 holliday resolvase complex|Mus81-Eme1 complex|resolvasome|Mus81-Eme2 complex|Mus81-Eme2 holliday resolvase complex													cellular_component											owl:Class	
GO:0043095	biolink:NamedThing	regulation of GTP cyclohydrolase I activity	Any process that modulates the activity of the enzyme GTP cyclohydrolase I.	got7fsn_ti														biological_process											owl:Class	
GO:1904783	biolink:NamedThing	positive regulation of NMDA glutamate receptor activity	Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity.	got7fsn_ti	activation of N-methyl-D-aspartate selective glutamate receptor activity|upregulation of NMDA receptor|upregulation of N-methyl-D-aspartate selective glutamate receptor activity|up regulation of NMDA receptor|positive regulation of N-methyl-D-aspartate selective glutamate receptor activity|up regulation of NMDA glutamate receptor activity|upregulation of NMDA glutamate receptor activity|activation of NMDA receptor|up-regulation of N-methyl-D-aspartate selective glutamate receptor activity|positive regulation of NMDA receptor|up-regulation of NMDA glutamate receptor activity|activation of NMDA glutamate receptor activity|up regulation of N-methyl-D-aspartate selective glutamate receptor activity|up-regulation of NMDA receptor						mr	2015-10-30T19:39:37Z						biological_process											owl:Class	
PR:000001546	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004275	biolink:NamedThing	obsolete enteropeptidase activity	OBSOLETE. Catalysis of the selective cleavage of Lys6-Ile7 bond in trypsinogen.	got7fsn_ti	enterokinase activity|enteropeptidase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905847	biolink:NamedThing	negative regulation of cellular response to oxidopamine	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine.	got7fsn_ti	down-regulation of cellular response to oxidopamine|downregulation of cellular response to oxidopamine|inhibition of cellular response to oxidopamine|down regulation of cellular response to oxidopamine						rz	2017-01-19T10:46:55Z						biological_process											owl:Class	
GO:1901676	biolink:NamedThing	positive regulation of histone H3-K27 acetylation	Any process that activates or increases the frequency, rate or extent of histone H3-K27 acetylation.	got7fsn_ti	up regulation of histone H3K27 acetylation|up-regulation of histone H3-K27 acetylation|upregulation of histone H3-K27 acetylation|up regulation of histone H3 acetylation at K27|up-regulation of histone H3 acetylation at K27|positive regulation of histone H3 acetylation at K27|up-regulation of histone H3K27 acetylation|upregulation of histone H3K27 acetylation|positive regulation of histone H3K27 acetylation|activation of histone H3-K27 acetylation|activation of histone H3K27 acetylation|upregulation of histone H3 acetylation at K27|activation of histone H3 acetylation at K27|up regulation of histone H3-K27 acetylation						vk	2012-11-22T12:06:45Z						biological_process											owl:Class	
GO:0051784	biolink:NamedThing	negative regulation of nuclear division	Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.	got7fsn_ti	down regulation of nuclear division|downregulation of nuclear division|inhibition of nuclear division|down-regulation of nuclear division													biological_process											owl:Class	
GO:0051637	biolink:NamedThing	obsolete Gram-positive bacterial cell surface binding	OBSOLETE. Binding to a component on the surface of a Gram-positive bacterium.	got7fsn_ti	Gram-positive bacterium cell surface binding|Gram-positive bacterium binding|Gram-positive bacterial cell surface binding|Gram-positive bacterial binding|binding to Gram-positive bacterium				This term was made obsolete because it is an unnecessary grouping term and was causing confusion.	GO:0050830|GO:0003823				True	GO:0051076			molecular_function											owl:Class	
GO:1903548	biolink:NamedThing	negative regulation of growth hormone activity	Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity.	got7fsn_ti	inhibition of pituitary growth hormone activity|negative regulation of pituitary growth hormone activity|down-regulation of placental growth hormone activity|down-regulation of growth hormone activity|negative regulation of GH activity|negative regulation of placental growth hormone activity|inhibition of placental growth hormone activity|down regulation of GH activity|down regulation of placental growth hormone activity|downregulation of GH activity|down-regulation of GH activity|inhibition of GH activity|downregulation of placental growth hormone activity|down regulation of pituitary growth hormone activity|downregulation of pituitary growth hormone activity|down regulation of growth hormone activity|down-regulation of pituitary growth hormone activity|inhibition of growth hormone activity|downregulation of growth hormone activity						mr	2014-10-20T15:18:45Z						biological_process											owl:Class	
GO:0032238	biolink:NamedThing	adenosine transport	The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0009878	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072621	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905494	biolink:NamedThing	negative regulation of G-quadruplex DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding.	got7fsn_ti	downregulation of G quadruplex DNA binding|downregulation of tetraplex DNA binding|down regulation of G quartet DNA binding|down-regulation of quadruplex DNA binding|inhibition of G quartet DNA binding|negative regulation of G-DNA binding|down regulation of quadruplex DNA binding|negative regulation of G-quartet DNA binding|down-regulation of tetraplex DNA binding|down-regulation of G quartet DNA binding|down-regulation of G-DNA binding|down regulation of G quadruplex DNA binding|inhibition of G-DNA binding|down regulation of tetraplex DNA binding|down-regulation of G quadruplex DNA binding|inhibition of G-quadruplex DNA binding|negative regulation of quadruplex DNA binding|inhibition of G quadruplex DNA binding|negative regulation of G quartet DNA binding|negative regulation of tetraplex DNA binding|downregulation of G-DNA binding|down regulation of G-DNA binding|downregulation of G-quadruplex DNA binding|down-regulation of G-quartet DNA binding|downregulation of quadruplex DNA binding|inhibition of G-quartet DNA binding|inhibition of tetraplex DNA binding|down-regulation of G-quadruplex DNA binding|negative regulation of G quadruplex DNA binding|inhibition of quadruplex DNA binding|downregulation of G-quartet DNA binding|downregulation of G quartet DNA binding|down regulation of G-quartet DNA binding|down regulation of G-quadruplex DNA binding						ans	2016-09-26T14:53:29Z						biological_process											owl:Class	
GO:0032759	biolink:NamedThing	positive regulation of TRAIL production	Any process that activates or increases the frequency, rate, or extent of TRAIL production.	got7fsn_ti	up-regulation of TRAIL production|positive regulation of TRAIL biosynthetic process|up regulation of TRAIL production|stimulation of TRAIL production|upregulation of TRAIL production|activation of TRAIL production										GO:0045556			biological_process											owl:Class	
GO:1900039	biolink:NamedThing	positive regulation of cellular response to hypoxia	Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia.	got7fsn_ti	up-regulation of cellular response to lowered oxygen tension|activation of cellular response to hypoxic stress|activation of cellular response to hypoxia|upregulation of cellular response to hypoxic stress|up regulation of cellular response to hypoxia|upregulation of cellular response to lowered oxygen tension|activation of cellular response to lowered oxygen tension|up-regulation of cellular response to hypoxia|up regulation of cellular response to hypoxic stress|positive regulation of cellular response to lowered oxygen tension|upregulation of cellular response to hypoxia|up-regulation of cellular response to hypoxic stress|up regulation of cellular response to lowered oxygen tension|positive regulation of cellular response to hypoxic stress						yaf	2012-01-17T09:29:19Z						biological_process											owl:Class	
GO:0019743	biolink:NamedThing	hopanoid catabolic process	The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.	got7fsn_ti	hopanoid catabolism|hopanoid breakdown|hopanoid degradation													biological_process											owl:Class	
GO:0034168	biolink:NamedThing	negative regulation of toll-like receptor 10 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway.	got7fsn_ti	negative regulation of TLR10 signaling pathway|negative regulation of toll-like receptor 10 signalling pathway													biological_process											owl:Class	
GO:2000220	biolink:NamedThing	regulation of pseudohyphal growth	Any process that modulates the frequency, rate or extent of pseudohyphal growth.	got7fsn_ti							mah	2010-11-03T04:36:56Z						biological_process											owl:Class	
GO:2000071	biolink:NamedThing	regulation of defense response by callose deposition	Any process that modulates the frequency, rate or extent of defense response by callose deposition.	got7fsn_ti	regulation of callose deposition during defense response|regulation of callose localization during defense response						tb	2010-08-23T11:34:01Z						biological_process											owl:Class	
GO:0032180	biolink:NamedThing	ubiquinone biosynthetic process from tyrosine	The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate.	got7fsn_ti														biological_process											owl:Class	
GO:1904741	biolink:NamedThing	obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation.	got7fsn_ti	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter, global|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of global transcription from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		tb	2015-10-15T21:40:43Z		True				biological_process											owl:Class	
GO:1901292	biolink:NamedThing	nucleoside phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.	got7fsn_ti	nucleoside phosphate catabolism|nucleoside phosphate breakdown|nucleoside phosphate degradation						bf	2012-08-20T12:33:25Z						biological_process											owl:Class	
GO:0032928	biolink:NamedThing	regulation of superoxide anion generation	Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.	got7fsn_ti	regulation of superoxide release													biological_process											owl:Class	
GO:0075168	biolink:NamedThing	obsolete regulation of protein kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont protein kinase-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0016227	biolink:NamedThing	obsolete tRNA sulfurtransferase activity	OBSOLETE. Catalysis of the reaction: L-cysteine + 'activated' tRNA = L-serine + tRNA containing a thionucleotide.	got7fsn_ti	transfer ribonucleate sulfurtransferase activity|RNA sulfurtransferase activity|transfer RNA thiolase activity|tRNA sulphurtransferase activity|ribonucleate sulfurtransferase activity|tRNA sulfurtransferase activity|L-cysteine:tRNA sulfurtransferase activity|transfer RNA sulfurtransferase activity			GO:0034227	This term was made obsolete because tRNA thionucleotide formation is a multistep process; there is no single reaction in which cysteine reacts with an activated tRNA directly	GO:0016783				True				molecular_function											owl:Class	
GO:0004432	biolink:NamedThing	obsolete 1-phosphatidylinositol-4-phosphate kinase, class IA	OBSOLETE. A class I PI3K activated by tyrosine phosphorylation events.	got7fsn_ti	1-phosphatidylinositol-4-phosphate kinase, class IA				This term was made obsolete because it is not a valid molecular function.	GO:0016308				True				molecular_function											owl:Class	
GO:0033013	biolink:NamedThing	tetrapyrrole metabolic process	The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.	got7fsn_ti	tetrapyrrole metabolism													biological_process											owl:Class	
CHEBI:58937	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902382	biolink:NamedThing	11-oxo-beta-amyrin catabolic process	The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin.	got7fsn_ti	11-oxo-beta-amyrin breakdown|11-oxo-beta-amyrin degradation|11-oxo-beta-amyrin catabolism						ms	2013-09-03T12:55:38Z						biological_process											owl:Class	
GO:0019026	biolink:NamedThing	obsolete negative sense viral genome	OBSOLETE. A single stranded RNA genome with the opposite nucleotide polarity as mRNA.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:1905872	biolink:NamedThing	negative regulation of protein localization to cell leading edge	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge.	got7fsn_ti	downregulation of protein localisation in cell leading edge|negative regulation of protein localisation to cell leading edge|downregulation of protein localization to cell leading edge|downregulation of protein localization in cell leading edge|down regulation of protein localization to cell leading edge|down-regulation of protein localisation in cell leading edge|down regulation of protein localisation to cell leading edge|down-regulation of protein localization to cell leading edge|down regulation of protein localisation in cell leading edge|inhibition of protein localisation to cell leading edge|down regulation of protein localization in cell leading edge|downregulation of protein localisation to cell leading edge|down-regulation of protein localization in cell leading edge|negative regulation of protein localization in cell leading edge|inhibition of protein localization to cell leading edge|down-regulation of protein localisation to cell leading edge|inhibition of protein localization in cell leading edge|negative regulation of protein localisation in cell leading edge|inhibition of protein localisation in cell leading edge						sl	2017-01-27T19:35:04Z						biological_process											owl:Class	
GO:0009910	biolink:NamedThing	negative regulation of flower development	Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.	got7fsn_ti	downregulation of flower development|inhibition of flower development|down-regulation of flower development|down regulation of flower development													biological_process											owl:Class	
GO:0051582	biolink:NamedThing	positive regulation of neurotransmitter uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.	got7fsn_ti	stimulation of neurotransmitter uptake|up regulation of neurotransmitter uptake|up-regulation of neurotransmitter uptake|activation of neurotransmitter uptake|positive regulation of neurotransmitter import|upregulation of neurotransmitter uptake													biological_process											owl:Class	
GO:0075076	biolink:NamedThing	obsolete positive regulation by host of symbiont adenylate cyclase activity	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		This term was obsoleted because it represents a molecular function.			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1905044	biolink:NamedThing	regulation of Schwann cell proliferation involved in axon regeneration	Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.	got7fsn_ti							rph	2016-03-11T14:47:35Z						biological_process											owl:Class	
GO:1900700	biolink:NamedThing	positive regulation of o-orsellinic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process.	got7fsn_ti	up-regulation of o-orsellinic acid biosynthesis|activation of o-orsellinic acid biosynthesis|upregulation of o-orsellinic acid biosynthetic process|positive regulation of o-orsellinic acid synthesis|up regulation of o-orsellinic acid biosynthesis|activation of o-orsellinic acid biosynthetic process|activation of o-orsellinic acid anabolism|activation of o-orsellinic acid synthesis|up regulation of o-orsellinic acid biosynthetic process|activation of o-orsellinic acid formation|up regulation of o-orsellinic acid anabolism|positive regulation of o-orsellinic acid formation|up-regulation of o-orsellinic acid anabolism|upregulation of o-orsellinic acid anabolism|positive regulation of o-orsellinic acid anabolism|up regulation of o-orsellinic acid formation|up-regulation of o-orsellinic acid formation|up-regulation of o-orsellinic acid biosynthetic process|positive regulation of o-orsellinic acid biosynthesis|upregulation of o-orsellinic acid formation|upregulation of o-orsellinic acid biosynthesis|upregulation of o-orsellinic acid synthesis|up-regulation of o-orsellinic acid synthesis|up regulation of o-orsellinic acid synthesis						di	2012-05-22T04:57:16Z						biological_process											owl:Class	
GO:1905017	biolink:NamedThing	positive regulation of isoleucine-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity.	got7fsn_ti	activation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of isoleucyl-transfer ribonucleate synthetase activity|positive regulation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of isoleucyl-tRNA synthetase activity|upregulation of isoleucine-tRNA ligase activity|upregulation of isoleucyl-tRNA synthetase activity|activation of isoleucine-tRNA synthetase activity|up regulation of isoleucine-tRNA synthetase activity|positive regulation of isoleucine translase activity|up regulation of isoleucyl-tRNA synthetase activity|up-regulation of isoleucine-tRNA ligase activity|up-regulation of isoleucine-tRNA synthetase activity|up-regulation of isoleucine-transfer RNA ligase activity|positive regulation of isoleucyl-transfer RNA synthetase activity|positive regulation of isoleucine-transfer RNA ligase activity|upregulation of L-isoleucine:tRNAIle ligase (AMP-forming)|positive regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up regulation of isoleucine-tRNA ligase activity|up-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|upregulation of isoleucine translase activity|up regulation of isoleucyl-transfer RNA synthetase activity|up-regulation of isoleucine translase activity|activation of isoleucyl-transfer RNA synthetase activity|up regulation of isoleucine-transfer RNA ligase activity|upregulation of isoleucine-transfer RNA ligase activity|up regulation of isoleucine translase activity|positive regulation of isoleucyl-tRNA synthetase activity|up-regulation of isoleucyl-transfer RNA synthetase activity|activation of L-isoleucine:tRNAIle ligase (AMP-forming)|activation of isoleucine-tRNA ligase activity|upregulation of isoleucine-tRNA synthetase activity|upregulation of isoleucyl-transfer ribonucleate synthetase activity|positive regulation of isoleucine-tRNA synthetase activity|up regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up regulation of isoleucyl-transfer ribonucleate synthetase activity|activation of isoleucine-transfer RNA ligase activity|activation of isoleucyl-tRNA synthetase activity|upregulation of isoleucyl-transfer RNA synthetase activity|activation of isoleucine translase activity						sl	2016-03-03T19:01:06Z						biological_process											owl:Class	
GO:0099699	biolink:NamedThing	integral component of synaptic membrane	The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti							dos	2017-05-25T17:22:18Z						cellular_component											owl:Class	
GO:0090297	biolink:NamedThing	positive regulation of mitochondrial DNA replication	Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.	got7fsn_ti	positive regulation of mitochondrial DNA synthesis						tb	2010-03-12T03:58:25Z						biological_process											owl:Class	
GO:0004681	biolink:NamedThing	obsolete casein kinase I activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	casein kinase I activity			GO:0004674	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0030106	biolink:NamedThing	obsolete MHC class I receptor activity	OBSOLETE. A major histocompatibility complex class I receptor. These display processed antigens from the endocytosed bacteria. MHC class I proteins can form complexes with processed antigen peptides only if the antigen is synthesized in the same cell. As a consequence, T lymphocytes can only bind to class-I-positive cells that are synthesizing the antigen (e.g. virus-infected cells).	got7fsn_ti	MHC class I receptor activity|class I major histocompatibility complex antigen|major histocompatibility complex class I receptor				This term was made obsolete because the definition is ambiguous and contains incorrect information. To update annotations of gene products that act as receptors for MHC class I protein complexes, use the molecular function term 'MHC class I receptor activity ; GO:0032393'; to update annotations of gene products which are components of MHC class I protein complexes, use the cellular component term 'MHC class I protein complex ; GO:0042612'.	GO:0032393|GO:0042612				True				molecular_function											owl:Class	
GO:1901408	biolink:NamedThing	negative regulation of phosphorylation of RNA polymerase II C-terminal domain	Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.	got7fsn_ti	inhibition of CTD domain phosphorylation of RNA polymerase II|negative regulation of generation of II(0) form of RNA polymerase II|inhibition of generation of II(0) form of RNA polymerase II|down-regulation of CTD domain phosphorylation of RNA polymerase II|downregulation of generation of hyperphosphorylated CTD of RNA polymerase II|down regulation of CTD domain phosphorylation of RNA polymerase II|downregulation of generation of II(0) form of RNA polymerase II|down-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|inhibition of hyperphosphorylation of RNA polymerase II C-terminal domain|inhibition of generation of hyperphosphorylated CTD of RNA polymerase II|downregulation of phosphorylation of RNA polymerase II C-terminal domain|down regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|negative regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|down-regulation of phosphorylation of RNA polymerase II C-terminal domain|down regulation of generation of hyperphosphorylated CTD of RNA polymerase II|downregulation of hyperphosphorylation of RNA polymerase II C-terminal domain|downregulation of CTD domain phosphorylation of RNA polymerase II|down regulation of generation of II(0) form of RNA polymerase II|negative regulation of CTD domain phosphorylation of RNA polymerase II|down-regulation of generation of II(0) form of RNA polymerase II|down-regulation of generation of hyperphosphorylated CTD of RNA polymerase II|down regulation of phosphorylation of RNA polymerase II C-terminal domain|negative regulation of generation of hyperphosphorylated CTD of RNA polymerase II|inhibition of phosphorylation of RNA polymerase II C-terminal domain						vw	2012-10-01T14:40:58Z						biological_process											owl:Class	
GO:2001264	biolink:NamedThing	negative regulation of C-C chemokine binding	Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding.	got7fsn_ti							yaf	2011-12-09T01:14:01Z						biological_process											owl:Class	
GO:0120248	biolink:NamedThing	acetylenic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).	got7fsn_ti	alkyne substituted compound catabolic process|alkyne substituted compound breakdown|alkyne substituted compound degradation|alkyne substituted compound catabolism	https://github.com/geneontology/go-ontology/issues/19842					krc	2020-08-18T01:02:52Z						biological_process											owl:Class	
GO:0140281	biolink:NamedThing	positive regulation of mitotic division septum assembly	Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	got7fsn_ti	activation of mitotic division septum assembly|upregulation of division septum formation involved in mitotic cell cycle|activation of septin assembly and septum formation involved in mitotic cell cycle|positive regulation of mitotic division septum assembly|positive regulation of formation of division septum involved in mitotic cell cycle|activation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up regulation of mitotic division septum assembly|up-regulation of mitotic division septum assembly|up-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up-regulation of division septum formation involved in mitotic cell cycle|up regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|upregulation of septin assembly and septum formation involved in mitotic cell cycle|positive regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up-regulation of formation of division septum involved in mitotic cell cycle|activation of formation of division septum involved in mitotic cell cycle|up regulation of division septum formation involved in mitotic cell cycle|up regulation of formation of division septum involved in mitotic cell cycle|positive regulation of septin assembly and septum formation involved in mitotic cell cycle|upregulation of formation of division septum involved in mitotic cell cycle|activation of division septum formation involved in mitotic cell cycle|up-regulation of septin assembly and septum formation involved in mitotic cell cycle|upregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up regulation of septin assembly and septum formation involved in mitotic cell cycle|positive regulation of division septum formation involved in mitotic cell cycle						pg	2018-10-08T10:03:30Z						biological_process											owl:Class	
GO:1905439	biolink:NamedThing	response to chondroitin 6'-sulfate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.	got7fsn_ti							cvs	2016-09-14T18:56:12Z						biological_process											owl:Class	
GO:0045632	biolink:NamedThing	negative regulation of mechanoreceptor differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation.	got7fsn_ti	downregulation of mechanoreceptor differentiation|down regulation of mechanoreceptor differentiation|inhibition of mechanoreceptor differentiation|down-regulation of mechanoreceptor differentiation													biological_process											owl:Class	
GO:0062028	biolink:NamedThing	regulation of stress granule assembly	Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.	got7fsn_ti							dph	2018-04-16T19:12:41Z						biological_process											owl:Class	
GO:0140216	biolink:NamedThing	negative regulation of D-aspartate import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15041					pg	2018-04-11T15:43:25Z						biological_process											owl:Class	
GO:0038071	biolink:NamedThing	obsolete MAP kinase activity involved in conjugation with cellular fusion	OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.	got7fsn_ti	MAPK activity involved in conjugation with cellular fusion				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:31:57Z		True				molecular_function											owl:Class	
GO:0035421	biolink:NamedThing	obsolete activation of MAPKK activity involved in innate immune response	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18000					bf	2010-03-29T01:26:44Z		True				biological_process											owl:Class	
GO:1904892	biolink:NamedThing	regulation of receptor signaling pathway via STAT	Any process that modulates the frequency, rate or extent of receptor signaling via STAT.	got7fsn_ti	regulation of STAT signalling pathway|regulation of kinase activated-STAT cascade|regulation of kinase-STAT cascade						pr	2016-01-08T08:14:33Z						biological_process											owl:Class	
GO:0015583	biolink:NamedThing	obsolete beta-glucoside [arbutin-salicin-cellobiose] permease activity	OBSOLETE. Catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). The beta-glucoside may be arbutin, salicin or cellobiose.	got7fsn_ti	beta-glucoside [arbutin-salicin-cellobiose] permease activity				This term was made obsolete because it arbitrarily groups three substrates.					True				molecular_function											owl:Class	
GO:1902783	biolink:NamedThing	cellular response to decane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.	got7fsn_ti							tt	2014-03-21T12:50:14Z						biological_process											owl:Class	
GO:0019470	biolink:NamedThing	4-hydroxyproline catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.	got7fsn_ti	4-hydroxyproline breakdown|4-hydroxyproline degradation|4-hydroxyproline catabolism											MetaCyc:HYDROXYPRODEG-PWY		biological_process											owl:Class	
GO:1900107	biolink:NamedThing	regulation of nodal signaling pathway	Any process that modulates the frequency, rate or extent of nodal signaling pathway.	got7fsn_ti	regulation of nodal signalling pathway|regulation of nodal signaling						bf	2012-02-16T03:34:19Z						biological_process											owl:Class	
GO:2000601	biolink:NamedThing	positive regulation of Arp2/3 complex-mediated actin nucleation	Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.	got7fsn_ti	positive regulation of branched actin filament nucleation|positive regulation of actin filament branch nucleation						bf	2011-04-14T12:35:44Z						biological_process											owl:Class	
GO:1900941	biolink:NamedThing	regulation of (Z)-nonadeca-1,14-diene biosynthetic process	Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.	got7fsn_ti	regulation of (Z)-nonadeca-1,14-diene anabolism|regulation of (Z)-nonadeca-1,14-diene synthesis|regulation of (Z)-nonadeca-1,14-diene biosynthesis|regulation of (Z)-nonadeca-1,14-diene formation						tt	2012-06-14T03:17:32Z						biological_process											owl:Class	
GO:0019861	biolink:NamedThing	obsolete flagellum	OBSOLETE. Long whiplike or feathery structures borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium.	got7fsn_ti	flagellum				This term was made obsolete because it was an unnecessary grouping term. Eukaryotic flagella were deemed to be equivalent to cilia and merged, so the only remaining child to this term was 'bacterial-type flagellum ; GO:0009288'.	GO:0005929|GO:0009288				True	GO:0008223	Wikipedia:Flagellum		cellular_component											owl:Class	
GO:0019428	biolink:NamedThing	allantoin biosynthetic process	The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.	got7fsn_ti	allantoin anabolism|allantoin formation|allantoin biosynthesis|allantoin synthesis											MetaCyc:URSIN-PWY		biological_process											owl:Class	
GO:1904923	biolink:NamedThing	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization.	got7fsn_ti							pad	2016-01-26T11:23:50Z						biological_process											owl:Class	
GO:0031115	biolink:NamedThing	negative regulation of microtubule polymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.	got7fsn_ti	down-regulation of microtubule polymerization|downregulation of microtubule polymerization|inhibition of microtubule polymerization|down regulation of microtubule polymerization													biological_process											owl:Class	
GO:0090125	biolink:NamedThing	cell-cell adhesion involved in synapse maturation	The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.	got7fsn_ti	trans-synaptic adhesion						tb	2009-12-07T02:43:24Z						biological_process											owl:Class	
GO:1900923	biolink:NamedThing	regulation of glycine import across plasma membrane	Any process that modulates the frequency, rate or extent of glycine import into a cell.	got7fsn_ti	regulation of glycine import						al	2012-06-13T07:40:11Z						biological_process											owl:Class	
GO:0004277	biolink:NamedThing	obsolete granzyme A activity	OBSOLETE. Catalysis of the hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: Arg-Xaa > Lys-Xaa > Phe-Xaa in small molecule substrates.	got7fsn_ti	granzyme A activity|TSP-1|T-cell derived serine proteinase|cytotoxic T lymphocyte serine protease|T-cell associated protease 1|HuTPS|CTLA3|cytotoxic T-lymphocyte proteinase 1 activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0051161	biolink:NamedThing	arabitol metabolic process	The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.	got7fsn_ti	arabitol metabolism													biological_process											owl:Class	
GO:0009750	biolink:NamedThing	response to fructose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.	got7fsn_ti	response to fructose stimulus													biological_process											owl:Class	
GO:0019612	biolink:NamedThing	4-toluenecarboxylate catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.	got7fsn_ti	4-toluenecarboxylate catabolism|4-toluenecarboxylate breakdown|4-toluenecarboxylate degradation|p-toluate catabolic process|p-toluate catabolism											MetaCyc:4TOLCARBDEG-PWY		biological_process											owl:Class	
CL:0002633	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010724	biolink:NamedThing	regulation of definitive erythrocyte differentiation	Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.	got7fsn_ti	regulation of definitive RBC differentiation|regulation of definitive red blood cell differentiation|regulation of definitive erythropoiesis													biological_process											owl:Class	
GO:0039711	biolink:NamedThing	cytoplasmic helical capsid assembly	The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome.	got7fsn_ti							bf	2013-11-28T15:23:39Z						biological_process											owl:Class	
GO:2000531	biolink:NamedThing	obsolete regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of the biosynthesis of fatty acids, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		dph	2011-03-24T12:18:33Z		True				biological_process											owl:Class	
GO:0031937	biolink:NamedThing	obsolete positive regulation of chromatin silencing	OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin silencing.	got7fsn_ti	positive regulation of heterochromatic silencing|upregulation of chromatin silencing|stimulation of chromatin silencing|up regulation of chromatin silencing|up-regulation of chromatin silencing|activation of chromatin silencing	https://github.com/geneontology/go-ontology/issues/22060			This term was obsoleted because it was too vague: regulation of chromatin (gene) silencing takes place via upstream signaling pathways.					True				biological_process											owl:Class	
GO:0036108	biolink:NamedThing	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).	got7fsn_ti	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate anabolism|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate synthesis|undecaprenyl phosphate alpha-L-Ara4N biosynthesis|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate formation|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthesis						bf	2012-02-06T02:58:03Z						biological_process											owl:Class	
GO:0036494	biolink:NamedThing	positive regulation of translation initiation in response to endoplasmic reticulum stress	Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.	got7fsn_ti	positive regulation of translation initiation in response to ER stress						bf	2015-02-05T10:11:32Z						biological_process											owl:Class	
CHEBI:24591	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045970	biolink:NamedThing	negative regulation of juvenile hormone catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.	got7fsn_ti	negative regulation of juvenile hormone breakdown|downregulation of juvenile hormone catabolic process|negative regulation of juvenile hormone catabolism|down-regulation of juvenile hormone catabolic process|negative regulation of juvenile hormone degradation|down regulation of juvenile hormone catabolic process|inhibition of juvenile hormone catabolic process													biological_process											owl:Class	
GO:1905095	biolink:NamedThing	negative regulation of apolipoprotein A-I-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.	got7fsn_ti	down regulation of apolipoprotein A-I-mediated signalling pathway|negative regulation of apolipoprotein A-I-mediated signalling pathway|inhibition of apolipoprotein A-I-mediated signaling pathway|downregulation of apolipoprotein A-I-mediated signaling pathway|down regulation of apolipoprotein A-I-mediated signaling pathway|down-regulation of apolipoprotein A-I-mediated signalling pathway|inhibition of apolipoprotein A-I-mediated signalling pathway|down-regulation of apolipoprotein A-I-mediated signaling pathway|downregulation of apolipoprotein A-I-mediated signalling pathway						bc	2016-03-31T11:33:58Z						biological_process											owl:Class	
GO:0150075	biolink:NamedThing	negative regulation of protein-glutamine gamma-glutamyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.	got7fsn_ti							bc	2018-07-25T10:10:24Z						biological_process											owl:Class	
GO:1902791	biolink:NamedThing	undecan-2-one biosynthetic process	The chemical reactions and pathways resulting in the formation of undecan-2-one.	got7fsn_ti	undecan-2-one synthesis|undecan-2-one formation|undecan-2-one biosynthesis|undecan-2-one anabolism						tt	2014-03-22T02:13:07Z						biological_process											owl:Class	
GO:0044118	biolink:NamedThing	obsolete development of symbiont in host cell	OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20305			This term was obsoleted because it represents both a process and a location.		jl	2009-07-30T03:52:00Z		True				biological_process											owl:Class	
GO:0006373	biolink:NamedThing	obsolete 3'-splice site cleavage, exon ligation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	3'-splice site cleavage, exon ligation				This term was made obsolete because it represents a molecular function.	GO:0000388|GO:0000386|GO:0000393				True				biological_process											owl:Class	
GO:0052220	biolink:NamedThing	obsolete positive aerotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive aerotaxis in response to environment of other organism|positive aerotaxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1902010	biolink:NamedThing	negative regulation of translation in response to endoplasmic reticulum stress	Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.	got7fsn_ti	negative regulation of protein biosynthetic process involved in ER stress response|down regulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein synthesis involved in ER stress response|down-regulation of protein biosynthetic process involved in ER stress response|negative regulation of protein synthesis involved in response to ER stress|protein biosynthetic process inhibitor activity involved in response to endoplasmic reticulum stress|downregulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein anabolism involved in response to endoplasmic reticulum stress|negative regulation of protein biosynthetic process involved in response to ER stress|protein biosynthesis inhibitor activity involved in response to endoplasmic reticulum stress|negative regulation of translation involved in ER stress response|negative regulation of protein anabolism involved in ER stress response|protein biosynthetic process inhibitor activity involved in response to ER stress|negative regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|down-regulation of protein biosynthetic process involved in response to ER stress|down regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein formation involved in response to ER stress|negative regulation of protein formation involved in response to endoplasmic reticulum stress|down-regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein anabolism involved in response to ER stress|downregulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein formation involved in ER stress response|inhibition of protein biosynthetic process involved in ER stress response|inhibition of protein biosynthetic process involved in response to ER stress|protein biosynthetic process inhibitor activity involved in ER stress response|down regulation of protein biosynthetic process involved in ER stress response|inhibition of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein biosynthesis involved in response to endoplasmic reticulum stress|protein biosynthesis inhibitor activity involved in ER stress response|negative regulation of protein synthesis involved in response to endoplasmic reticulum stress|negative regulation of translation involved in response to ER stress|protein biosynthesis inhibitor activity involved in response to ER stress|negative regulation of protein biosynthesis involved in response to ER stress|downregulation of protein biosynthetic process involved in ER stress response|negative regulation of protein biosynthesis involved in ER stress response						dph	2013-03-22T13:43:26Z						biological_process											owl:Class	
GO:0090280	biolink:NamedThing	positive regulation of calcium ion import	Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.	got7fsn_ti	positive regulation of transmembrane calcium influx						tb	2010-02-08T05:11:20Z						biological_process											owl:Class	
GO:1902414	biolink:NamedThing	protein localization to cell junction	A process in which a protein is transported to, or maintained in, a location within a cell junction.	got7fsn_ti	protein localisation to cell junction|protein localization in cell junction|protein localisation in cell junction						tb	2013-09-13T16:55:57Z						biological_process											owl:Class	
GO:1900350	biolink:NamedThing	positive regulation of methane biosynthetic process from methylamine	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine.	got7fsn_ti	up regulation of methane biosynthetic process from methylamine|up-regulation of methane biosynthetic process from methylamine|activation of methane biosynthetic process from methylamine|upregulation of methane biosynthetic process from methylamine						tt	2012-04-06T02:12:12Z						biological_process											owl:Class	
GO:0035348	biolink:NamedThing	acetyl-CoA transmembrane transport	The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.	got7fsn_ti	acetyl-CoA membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:42:23Z						biological_process											owl:Class	
GO:0034235	biolink:NamedThing	GPI anchor binding	Binding to a glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.	got7fsn_ti	glycosylphosphatidylinositol binding				Note that this term should be used to annotate gene products that interact non-covalently with GPI anchors, and not proteins that have GPI anchors covalently attached.									molecular_function											owl:Class	
GO:0090123	biolink:NamedThing	lysosomal glycocalyx	The polysaccharide-based coating on the inner side of a lysosomal membrane. It may be involved in protecting the membrane from digestion by lysosomal enzymes.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19782					tb	2009-12-07T01:16:20Z						cellular_component											owl:Class	
GO:0019257	biolink:NamedThing	4-nitrotoluene metabolic process	The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor.	got7fsn_ti	4NT metabolism|4-nitrotoluene metabolism|4NT metabolic process													biological_process											owl:Class	
CL:0000365	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035344	biolink:NamedThing	hypoxanthine transport	The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	hypoxanthine transmembrane transport|6-hydroxypurine transport						bf	2010-03-04T10:39:55Z						biological_process											owl:Class	
GO:1904026	biolink:NamedThing	regulation of collagen fibril organization	Any process that modulates the frequency, rate or extent of collagen fibril organization.	got7fsn_ti	regulation of fibrillar collagen organization|regulation of collagen fibril organisation|regulation of collagen fibrillogenesis						ae	2015-03-12T12:36:52Z						biological_process											owl:Class	
GO:0018308	biolink:NamedThing	obsolete enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine	OBSOLETE. The transient modification of lysine by pyruvate to form N6-pyruvic acid 2-iminyl-L-lysine, found in the active site of dihydrodipicolinate synthase.	got7fsn_ti	enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine				This term was made obsolete because this process does not occur: the modification occurs before it can be an active site.					True				biological_process											owl:Class	
GO:0090316	biolink:NamedThing	positive regulation of intracellular protein transport	Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.	got7fsn_ti							tb	2010-04-16T03:45:07Z						biological_process											owl:Class	
GO:0099183	biolink:NamedThing	trans-synaptic signaling by BDNF, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		dos	2017-12-01T18:25:24Z						biological_process											owl:Class	
GO:0043858	biolink:NamedThing	arginine:ornithine antiporter activity	Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out).	got7fsn_ti	arginine-ornithine antiporter activity|ArcD|arginine/ornithine antiporter activity													molecular_function											owl:Class	
GO:1904121	biolink:NamedThing	phosphatidylethanolamine transfer activity	Removes phosphatidylethanolamine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	got7fsn_ti	phosphatidylethanolamine carrier activity|phosphatidylethanolamine transporter activity|intermembrane phosphatidylethanolamine transfer activity						sl	2015-04-07T22:51:34Z						molecular_function											owl:Class	
GO:0051545	biolink:NamedThing	negative regulation of elastin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.	got7fsn_ti	down regulation of elastin biosynthetic process|downregulation of elastin biosynthetic process|down-regulation of elastin biosynthetic process|inhibition of elastin biosynthetic process													biological_process											owl:Class	
GO:1903844	biolink:NamedThing	regulation of cellular response to transforming growth factor beta stimulus	Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.	got7fsn_ti	regulation of cellular response to TGF-beta stimulus|regulation of cellular response to TGFbeta stimulus						rph	2015-01-23T11:25:11Z						biological_process											owl:Class	
GO:0030455	biolink:NamedThing	obsolete MAPKKK cascade (mating sensu Fungi)	OBSOLETE. MAPKKK cascade involved in transducing mating pheromone signal in a fungus.	got7fsn_ti	MAPKKK cascade (mating sensu Fungi)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:1905233	biolink:NamedThing	response to codeine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.	got7fsn_ti							sl	2016-06-07T21:26:45Z						biological_process											owl:Class	
GO:1900967	biolink:NamedThing	positive regulation of methanophenazine metabolic process	Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process.	got7fsn_ti	upregulation of methanophenazine metabolism|activation of methanophenazine metabolism|up-regulation of methanophenazine metabolic process|up regulation of methanophenazine metabolic process|activation of methanophenazine metabolic process|positive regulation of methanophenazine metabolism|up regulation of methanophenazine metabolism|upregulation of methanophenazine metabolic process|up-regulation of methanophenazine metabolism						tt	2012-06-14T03:55:56Z						biological_process											owl:Class	
GO:0004403	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905656	biolink:NamedThing	positive regulation of artery smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction.	got7fsn_ti	activation of artery smooth muscle contraction|up regulation of artery smooth muscle contraction|up-regulation of artery smooth muscle contraction|upregulation of artery smooth muscle contraction						rph	2016-11-09T12:35:01Z						biological_process											owl:Class	
GO:1905922	biolink:NamedThing	negative regulation of acetylcholine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process.	got7fsn_ti	down-regulation of acetylcholine anabolism|down regulation of acetylcholine formation|down regulation of acetylcholine biosynthesis|inhibition of acetylcholine biosynthetic process|negative regulation of acetylcholine synthesis|downregulation of acetylcholine anabolism|negative regulation of acetylcholine anabolism|down-regulation of acetylcholine synthesis|downregulation of acetylcholine formation|negative regulation of acetylcholine formation|down-regulation of acetylcholine biosynthesis|downregulation of acetylcholine biosynthesis|down regulation of acetylcholine biosynthetic process|negative regulation of acetylcholine biosynthesis|inhibition of acetylcholine synthesis|inhibition of acetylcholine anabolism|down-regulation of acetylcholine formation|inhibition of acetylcholine biosynthesis|down regulation of acetylcholine anabolism|down regulation of acetylcholine synthesis|down-regulation of acetylcholine biosynthetic process|inhibition of acetylcholine formation|downregulation of acetylcholine biosynthetic process|downregulation of acetylcholine synthesis						bc	2017-02-08T13:08:39Z						biological_process											owl:Class	
UBERON:0005366	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046057	biolink:NamedThing	dADP catabolic process	The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).	got7fsn_ti	dADP catabolism|dADP breakdown|dADP degradation													biological_process											owl:Class	
GO:0046255	biolink:NamedThing	obsolete 2,4,6-trinitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene.	got7fsn_ti	2,4,6-trinitrotoluene anabolism|2,4,6-trinitrotoluene synthesis|2,4,6-trinitrotoluene formation|2,4,6-trinitrotoluene biosynthetic process|2,4,6-trinitrotoluene biosynthesis			GO:0018974	This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:2000580	biolink:NamedThing	obsolete regulation of microtubule motor activity, plus-end-directed	OBSOLETE. Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.	got7fsn_ti	regulation of plus-end-directed microtubule motor activity|regulation of ATP-dependent microtubule motor activity, plus-end-directed|regulation of kinesin activity|regulation of kinesin ATP phosphohydrolase (plus-end-directed)|regulation of plus-end-directed kinesin ATPase activity	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140659	bf	2011-04-05T08:39:43Z		True				biological_process											owl:Class	
GO:1904216	biolink:NamedThing	positive regulation of protein import into chloroplast stroma	Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma.	got7fsn_ti	upregulation of protein transport into chloroplast stroma|up regulation of protein import into chloroplast stroma|up regulation of chloroplast stroma protein import|positive regulation of protein transport into chloroplast stroma|up-regulation of chloroplast stroma protein import|upregulation of protein import into chloroplast stroma|positive regulation of chloroplast stroma protein import|activation of protein import into chloroplast stroma|activation of protein transport into chloroplast stroma|up-regulation of protein transport into chloroplast stroma|up regulation of protein transport into chloroplast stroma|up-regulation of protein import into chloroplast stroma|upregulation of chloroplast stroma protein import|activation of chloroplast stroma protein import						tb	2015-05-15T00:47:55Z						biological_process											owl:Class	
GO:0009256	biolink:NamedThing	10-formyltetrahydrofolate metabolic process	The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.	got7fsn_ti	10-formyltetrahydrofolate metabolism|10-formyl-THF metabolic process|10-formyl-THF metabolism													biological_process											owl:Class	
GO:0052377	biolink:NamedThing	obsolete evasion or tolerance by organism of symbiont-produced phytoalexins	OBSOLETE. The process by which an organism avoids the effects of phytoalexins produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	symbiont phytoalexin detoxification|evasion or tolerance by organism of symbiont phytoalexins|evasion or tolerance by organism of symbiont-produced phytoalexins|evasion or tolerance of phytoalexins produced by symbiont in response to organism				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0008615	biolink:NamedThing	pyridoxine biosynthetic process	The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.	got7fsn_ti	pyridoxine biosynthesis|pyridoxine formation|pyridoxine synthesis|pyridoxine anabolism													biological_process											owl:Class	
GO:1905317	biolink:NamedThing	inferior endocardial cushion morphogenesis	The developmental process by which an inferior endocardial cushion is generated and organized.	got7fsn_ti	ventral endocardial cushion morphogenesis						rl	2016-07-12T14:14:56Z						biological_process											owl:Class	
GO:0051104	biolink:NamedThing	DNA-dependent DNA replication DNA ligation	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication.	got7fsn_ti	DNA ligation during DNA-dependent DNA replication|DNA ligation involved in DNA-dependent DNA replication													biological_process											owl:Class	
GO:0036228	biolink:NamedThing	protein localization to nuclear inner membrane	A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane.	got7fsn_ti	protein targeting to INM|protein targeting to nuclear inner membrane						bf	2012-05-11T10:42:34Z						biological_process											owl:Class	
GO:0061338	biolink:NamedThing	obsolete atrioventricular node impulse conduction delay	OBSOLETE. A heart process that modulates the propagation of the signal that causes the heart muscle to contract.	got7fsn_ti	atrioventricular node impulse conduction delay				This term was made obsolete because it was created before the cardiac conduction overhaul, and represents a measurement rather than a process.	GO:0086016	dph	2010-09-29T08:55:53Z		True				biological_process											owl:Class	
GO:1900757	biolink:NamedThing	regulation of D-amino-acid oxidase activity	Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity.	got7fsn_ti	regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|regulation of L-amino acid:O2 oxidoreductase activity|regulation of new yellow enzyme						pm	2012-05-31T11:23:45Z						biological_process											owl:Class	
GO:1902627	biolink:NamedThing	regulation of assembly of large subunit precursor of preribosome	Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome.	got7fsn_ti	regulation of 66S preribosome assembly|regulation of preribosome, large subunit precursor formation|regulation of 66S preribosome formation						tb	2014-01-16T22:11:45Z						biological_process											owl:Class	
GO:0031400	biolink:NamedThing	negative regulation of protein modification process	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.	got7fsn_ti	down-regulation of protein modification|inhibition of protein modification|down regulation of protein modification|downregulation of protein modification													biological_process											owl:Class	
GO:0071803	biolink:NamedThing	positive regulation of podosome assembly	Any process that activates or increases the rate or extent of podosome assembly.	got7fsn_ti	upregulation of podosome assembly|activation of podosome assembly|up regulation of podosome assembly|stimulation of podosome assembly|up-regulation of podosome assembly						mah	2010-09-03T01:50:50Z						biological_process											owl:Class	
GO:1900620	biolink:NamedThing	acetate ester biosynthetic process	The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.	got7fsn_ti	acetate ester formation|acetate ester synthesis|acetyl ester biosynthetic process|acetyl ester biosynthesis|acetate ester biosynthesis|acetate ester anabolism						bf	2012-05-16T12:30:12Z						biological_process											owl:Class	
GO:0046671	biolink:NamedThing	negative regulation of retinal cell programmed cell death	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.	got7fsn_ti	down regulation of retinal programmed cell death|downregulation of retinal programmed cell death|down-regulation of retinal programmed cell death|negative regulation of retinal programmed cell death|inhibition of retinal programmed cell death													biological_process											owl:Class	
GO:1904131	biolink:NamedThing	negative regulation of convergent extension involved in neural plate elongation	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation.	got7fsn_ti	inhibition of convergent extension involved in neural plate elongation|downregulation of convergent extension involved in neural plate elongation|down regulation of convergent extension involved in neural plate elongation|down-regulation of convergent extension involved in neural plate elongation						dph	2015-04-10T21:13:27Z						biological_process											owl:Class	
GO:0046177	biolink:NamedThing	D-gluconate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.	got7fsn_ti	D-gluconate breakdown|D-gluconate catabolism|D-gluconate degradation											MetaCyc:GLUCONSUPER-PWY		biological_process											owl:Class	
GO:0061083	biolink:NamedThing	regulation of protein refolding	Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.	got7fsn_ti							dph	2010-04-26T01:07:54Z						biological_process											owl:Class	
GO:1900531	biolink:NamedThing	obsolete regulation of cell shape involved in cellular response to heat	OBSOLETE. Any regulation of cell shape that is involved in cellular response to heat.	got7fsn_ti	regulation of cell shape of cellular response to heat|regulation of cell shape of cellular response to heat stress|regulation of cell shape involved in cellular response to heat				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2012-05-08T01:51:00Z		True				biological_process											owl:Class	
GO:1905090	biolink:NamedThing	negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.	got7fsn_ti	negative regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|down-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|inhibition of parkin-mediated mitophagy in response to mitochondrial depolarization|negative regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|downregulation of parkin-mediated mitophagy in response to mitochondrial depolarization|down regulation of parkin-mediated mitophagy in response to mitochondrial depolarization						pad	2016-03-30T15:34:38Z						biological_process											owl:Class	
GO:1905712	biolink:NamedThing	cellular response to phosphatidylethanolamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.	got7fsn_ti	cellular response to PtdEtn|cellular response to PE|cellular response to phosphatidylethanolamines|cellular response to phosphatidyl(amino)ethanols						sl	2016-11-21T19:55:40Z						biological_process											owl:Class	
GO:1904397	biolink:NamedThing	negative regulation of neuromuscular junction development	Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development.	got7fsn_ti	negative regulation of neuromuscular junction organization|negative regulation of neuromuscular junction stability|down-regulation of neuromuscular junction organization|inhibition of neuromuscular junction organization|inhibition of neuromuscular junction stability|down regulation of NMJ stability|downregulation of neuromuscular junction stability|downregulation of NMJ stability|down-regulation of NMJ stability|downregulation of neuromuscular junction organization|down-regulation of neuromuscular junction development|down regulation of neuromuscular junction development|down regulation of neuromuscular junction stability|downregulation of neuromuscular junction development|down-regulation of neuromuscular junction stability|negative regulation of NMJ stability|inhibition of NMJ stability|inhibition of neuromuscular junction development|down regulation of neuromuscular junction organization						sl	2015-06-23T19:23:48Z						biological_process											owl:Class	
GO:0009128	biolink:NamedThing	purine nucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine nucleoside monophosphate breakdown|purine nucleoside monophosphate degradation|purine nucleoside monophosphate catabolism													biological_process											owl:Class	
GO:0039598	biolink:NamedThing	obsolete induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process	OBSOLETE. The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA) initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.	got7fsn_ti	induction by virus of host nuclear poly(A)-dependent mRNA catabolic process|induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process|virus-mediated host mRNA decay by hyperadenylation				This term was made obsolete because it is unclear what role the viral protein is playing in this process. and there is insufficient evidence to use this term for annotation.		bf	2012-07-04T04:44:16Z		True				biological_process											owl:Class	
GO:0052361	biolink:NamedThing	obsolete catabolism by organism of macromolecule in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism by organism of macromolecule in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0033247	biolink:NamedThing	regulation of penicillin catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti	regulation of penicillin degradation|regulation of penicillin breakdown|regulation of penicillin catabolism													biological_process											owl:Class	
GO:0043199	biolink:NamedThing	sulfate binding	Binding to sulfate, SO4(2-), a negatively charged small molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:1903845	biolink:NamedThing	negative regulation of cellular response to transforming growth factor beta stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.	got7fsn_ti	down regulation of cellular response to TGF-beta stimulus|downregulation of cellular response to transforming growth factor beta stimulus|downregulation of cellular response to TGFbeta stimulus|negative regulation of cellular response to TGF-beta stimulus|down-regulation of cellular response to transforming growth factor beta stimulus|inhibition of cellular response to TGF-beta stimulus|down regulation of cellular response to transforming growth factor beta stimulus|down-regulation of cellular response to TGF-beta stimulus|negative regulation of cellular response to TGFbeta stimulus|inhibition of cellular response to TGFbeta stimulus|inhibition of cellular response to transforming growth factor beta stimulus|down-regulation of cellular response to TGFbeta stimulus|down regulation of cellular response to TGFbeta stimulus|downregulation of cellular response to TGF-beta stimulus						rph	2015-01-23T11:25:21Z						biological_process											owl:Class	
GO:1904002	biolink:NamedThing	regulation of sebum secreting cell proliferation	Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation.	got7fsn_ti	regulation of sebocyte proliferation						hjd	2015-03-06T16:19:44Z						biological_process											owl:Class	
GO:0061964	biolink:NamedThing	negative regulation of entry into reproductive diapause	Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	got7fsn_ti							dph	2018-02-05T15:04:33Z						biological_process											owl:Class	
GO:2001274	biolink:NamedThing	obsolete negative regulation of glucose import in response to insulin stimulus	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose import in response to insulin stimulus.	got7fsn_ti	negative regulation of cellular glucose import in response to insulin stimulus	https://github.com/geneontology/go-ontology/issues/15961					vk	2011-12-13T12:29:38Z		True				biological_process											owl:Class	
GO:1901850	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process	The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin.	got7fsn_ti	coenzyme F0 metabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolism						yaf	2013-01-28T11:38:32Z						biological_process											owl:Class	
GO:1990128	biolink:NamedThing	obsolete pre-primosome complex involved in replication initiation	OBSOLETE. A protein-DNA complex involved in replication initiation at the origin of replication.	got7fsn_ti	pre-primosome complex involved in replication initiation				This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2013-06-24T10:29:39Z		True				cellular_component											owl:Class	
GO:1902360	biolink:NamedThing	conversion of ds siRNA to ss siRNA involved in gene silencing by small RNA	Any conversion of ds siRNA to ss siRNA that is involved in gene silencing by small RNA.	got7fsn_ti	conversion of ds siRNA to ss siRNA involved in RNAi-directed chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA interference-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in small RNA-mediated heterochromatic silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated transcriptional silencing|conversion of ds siRNA to ss siRNA involved in RNAi-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in chromatin silencing by small RNA|conversion of ds siRNA to ss siRNA involved in RNA interference-like chromatin silencing|conversion of ds siRNA to ss siRNA involved in RNA-mediated transcriptional silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-directed chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-like chromatin silencing|conversion of ds siRNA to ss siRNA involved in chromatin silencing by small RNA|conversion of ds siRNA to ss siRNA involved in RNA-mediated chromatin silencing|conversion of ds siRNA to ss siRNA involved in small RNA-mediated heterochromatic silencing	https://github.com/geneontology/go-ontology/issues/22058					bf	2013-08-15T10:06:18Z						biological_process											owl:Class	
GO:0140300	biolink:NamedThing	serine import into mitochondrion	The process in which serine is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti							pg	2018-12-13T15:17:50Z						biological_process											owl:Class	
GO:1905546	biolink:NamedThing	cellular response to phenylpropanoid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus.	got7fsn_ti							sl	2016-10-11T19:54:58Z						biological_process											owl:Class	
GO:2000703	biolink:NamedThing	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.	got7fsn_ti	negative regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|negative regulation of FGF receptor signalling pathway of ureteric bud formation|negative regulation of FGF receptor signaling pathway of ureteric bud formation|negative regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|negative regulation of FGFR signaling pathway of ureteric bud formation						yaf	2011-05-25T09:48:22Z						biological_process											owl:Class	
GO:0016916	biolink:NamedThing	obsolete inhibin	OBSOLETE. Either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.	got7fsn_ti	inhibin				This term was made obsolete because it represents a gene product.	GO:0046882|GO:0005160				True				molecular_function											owl:Class	
CL:0000501	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008575	biolink:NamedThing	obsolete proteasome ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP for channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome.	got7fsn_ti	proteasome ATPase activity				This term was made obsolete because it mentions a component term in the term text string.	GO:0016887				True				molecular_function											owl:Class	
GO:0015051	biolink:NamedThing	obsolete X-opioid receptor activity	OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors.	got7fsn_ti	X-opioid receptor activity				This term was made obsolete because the receptor is defined based on its pharmacological properties.	GO:0001626				True				molecular_function											owl:Class	
GO:0009108	biolink:NamedThing	obsolete coenzyme biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	got7fsn_ti	coenzyme biosynthesis|coenzyme formation|coenzyme and prosthetic group biosynthesis|coenzyme synthesis|coenzyme and prosthetic group biosynthetic process|coenzyme anabolism				1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group biosynthetic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True				biological_process											owl:Class	
GO:1900017	biolink:NamedThing	positive regulation of cytokine production involved in inflammatory response	Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.	got7fsn_ti	positive regulation of cytokine production involved in acute inflammatory response|up regulation of cytokine production involved in acute inflammatory response|up regulation of cytokine production involved in inflammatory response						rph	2012-01-11T09:34:35Z						biological_process											owl:Class	
GO:1904613	biolink:NamedThing	cellular response to 2,3,7,8-tetrachlorodibenzodioxine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.	got7fsn_ti	cellular response to dioxin|cellular response to TCDD						sl	2015-08-27T19:01:58Z						biological_process											owl:Class	
GO:1903355	biolink:NamedThing	negative regulation of distal tip cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration.	got7fsn_ti	down regulation of distal tip cell migration|downregulation of distal tip cell migration|down-regulation of distal tip cell migration|inhibition of distal tip cell migration						pr	2014-08-21T10:05:17Z						biological_process											owl:Class	
GO:0120215	biolink:NamedThing	positive regulation of histidine biosynthetic process	Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process.	got7fsn_ti	positive regulation of histidine synthesis|activation of histidine formation|positive regulation of histidine anabolism|up-regulation of histidine formation|up-regulation of histidine biosynthesis|up regulation of histidine formation|upregulation of histidine synthesis|up regulation of histidine anabolism|positive regulation of histidine biosynthesis|up regulation of histidine synthesis|activation of histidine biosynthesis|up-regulation of histidine biosynthetic process|upregulation of histidine formation|up regulation of histidine biosynthetic process|up regulation of histidine biosynthesis|activation of histidine anabolism|activation of histidine synthesis|upregulation of histidine anabolism|positive regulation of histidine formation|upregulation of histidine biosynthesis|up-regulation of histidine anabolism|up-regulation of histidine synthesis|upregulation of histidine biosynthetic process|activation of histidine biosynthetic process						krc	2019-06-27T20:57:28Z						biological_process											owl:Class	
GO:0019833	biolink:NamedThing	obsolete ice nucleation activity	OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation.	got7fsn_ti	ice nucleation activity				This term was made obsolete because it represents a biological process.	GO:0042309|GO:0050825				True				molecular_function											owl:Class	
GO:0052485	biolink:NamedThing	obsolete negative regulation by organism of symbiont inflammatory response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of symbiont inflammatory response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1903728	biolink:NamedThing	luteal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells.	got7fsn_ti	lutein cell differentiation						cjm	2014-12-10T01:36:43Z						biological_process											owl:Class	
GO:0000059	biolink:NamedThing	obsolete protein import into nucleus, docking	OBSOLETE. A protein complex assembly process that contributes to protein import into the nucleus, and that results in the association of a cargo protein, a carrier protein such as an importin alpha/beta heterodimer, and a nucleoporin located at the periphery of the nuclear pore complex.	got7fsn_ti	protein transport from cytoplasm to nucleus, docking|protein docking during protein-nucleus import|protein-nucleus import, docking|protein docking during protein import into nucleus|protein docking during protein transport from cytoplasm to nucleus				This term was made obsolete because the transient assembly is better captured as a protein-protein association, if at all.					True				biological_process											owl:Class	
GO:1904751	biolink:NamedThing	positive regulation of protein localization to nucleolus	Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus.	got7fsn_ti	up regulation of protein localisation in nucleolus|up-regulation of protein localization to nucleolus|upregulation of protein localisation in nucleolus|positive regulation of protein localisation to nucleolus|upregulation of protein localization in nucleolus|up regulation of protein localisation to nucleolus|positive regulation of protein localisation in nucleolus|activation of protein localisation in nucleolus|up regulation of protein localization in nucleolus|up-regulation of protein localisation in nucleolus|activation of protein localization to nucleolus|positive regulation of protein localization in nucleolus|upregulation of protein localisation to nucleolus|up regulation of protein localization to nucleolus|up-regulation of protein localization in nucleolus|up-regulation of protein localisation to nucleolus|activation of protein localisation to nucleolus|activation of protein localization in nucleolus|upregulation of protein localization to nucleolus						nc	2015-10-19T15:16:30Z						biological_process											owl:Class	
GO:0010125	biolink:NamedThing	mycothiol biosynthetic process	The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.	got7fsn_ti	mycothiol formation|mycothiol anabolism|mycothiol biosynthesis|mycothiol synthesis											MetaCyc:PWY1G-0		biological_process											owl:Class	
GO:0090452	biolink:NamedThing	lithium ion transmembrane transport	The directed movement of lithium ions across a membrane.	got7fsn_ti	lithium ion import|lithium ion uptake						tb	2012-09-24T14:04:41Z						biological_process											owl:Class	
GO:0045666	biolink:NamedThing	positive regulation of neuron differentiation	Any process that activates or increases the frequency, rate or extent of neuron differentiation.	got7fsn_ti	up-regulation of neuron differentiation|activation of neuron differentiation|stimulation of neuron differentiation|upregulation of neuron differentiation|up regulation of neuron differentiation													biological_process											owl:Class	
GO:0031285	biolink:NamedThing	regulation of sorocarp stalk cell differentiation	Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	regulation of stalk cell differentiation													biological_process											owl:Class	
GO:1902571	biolink:NamedThing	regulation of serine-type peptidase activity	Any process that modulates the frequency, rate or extent of serine-type peptidase activity.	got7fsn_ti	regulation of serine protease activity						krc	2013-12-10T18:16:58Z						biological_process											owl:Class	
GO:0031657	biolink:NamedThing	obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	OBSOLETE. Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.	got7fsn_ti	G1/S-specific regulation of cyclin-dependent protein kinase activity|regulation of cyclin-dependent protein kinase activity involved in G1/S|regulation of cyclin-dependent protein kinase activity during G1/S				The term has been obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:2000896	biolink:NamedThing	amylopectin metabolic process	The chemical reactions and pathways involving an amylopectin.	got7fsn_ti	Amylopectin metabolism						jl	2011-07-28T02:47:25Z						biological_process											owl:Class	
GO:0060609	biolink:NamedThing	apoptotic process involved in tube lumen cavitation	Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.	got7fsn_ti	apoptosis involved in tube lumen cavitation						dph	2009-05-15T10:05:39Z						biological_process											owl:Class	
GO:2001312	biolink:NamedThing	lysobisphosphatidic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.	got7fsn_ti	bis(monoacylglycerol) hydrogen phosphate biosynthetic process|LBPA synthesis|lysobisphosphatidic acid synthesis|bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthesis|LBPA biosynthesis|LBPA formation|bis(monoacylglycerol) hydrogen phosphate anabolism|bis(monoacylglycerol) hydrogen phosphate formation|bis(monoacylglycerol) hydrogen phosphate (BMP) synthesis|LBPA anabolism|lysobisphosphatidic acid formation|lysobisphosphatidic acid anabolism|bis(monoacylglycerol) hydrogen phosphate synthesis|bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthetic process|LBPA biosynthetic process|bis(monoacylglycerol) hydrogen phosphate (BMP) anabolism|bis(monoacylglycerol) hydrogen phosphate biosynthesis|lysobisphosphatidic acid biosynthesis|bis(monoacylglycerol) hydrogen phosphate (BMP) formation						bf	2012-03-16T09:31:31Z						biological_process											owl:Class	
GO:0009234	biolink:NamedThing	menaquinone biosynthetic process	The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.	got7fsn_ti	menaquinone biosynthesis|multiprenylmenaquinone biosynthetic process|menatetrenone biosynthetic process|multiprenylmenaquinone biosynthesis|vitamin K2 biosynthesis|menaquinone anabolism|menatetrenone biosynthesis|vitamin K2 biosynthetic process|menaquinone formation|menaquinone synthesis											MetaCyc:MENAQUINONESYN-PWY		biological_process											owl:Class	
GO:0015004	biolink:NamedThing	obsolete small blue copper electron carrier	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	small blue copper electron carrier			GO:0009055	This term was made obsolete because it does not represent a molecular function.					True				molecular_function											owl:Class	
GO:0039565	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by positive regulation of STAT1 catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT1 (signal transducer and activator of transcription-1) by promoting the ubiquitin-dependent degradation of STAT1, mediated by the proteasome.	got7fsn_ti	suppression by virus of host STAT1 activity by positive promotion of STAT1 proteasome-mediated degradation|targeting STAT1 for proteasome-mediated degradation|promotion by virus of proteosome-dependent STAT1 degradation				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T02:57:36Z		True				biological_process											owl:Class	
GO:0048277	biolink:NamedThing	obsolete nonexocytotic vesicle docking	OBSOLETE. The initial attachment of a transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, during a non-exocytotic process.	got7fsn_ti	nonexocytotic vesicle docking|non-exocytotic vesicle docking			GO:0048278	This term was made obsolete because it violates the principle of positivity.					True				biological_process											owl:Class	
GO:0071236	biolink:NamedThing	cellular response to antibiotic	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.	got7fsn_ti							mah	2009-12-03T02:23:49Z						biological_process											owl:Class	
GO:1904865	biolink:NamedThing	positive regulation of beta-catenin-TCF complex assembly	Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly.	got7fsn_ti	activation of beta-catenin/T-cell factor complex assembly|positive regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|activation of beta-catenin-TCF complex formation|upregulation of beta-catenin/lymphoid enhancer binding factor complex assembly|up regulation of beta-catenin/T-cell factor complex formation|upregulation of beta-catenin-TCF complex assembly|activation of beta-catenin/lymphoid enhancer binding factor complex assembly|up regulation of beta-catenin-TCF complex formation|up-regulation of beta-catenin/LEF complex formation|up regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|activation of beta-catenin/LEF complex formation|activation of beta-catenin/LEF complex assembly|up-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|up-regulation of beta-catenin/LEF complex assembly|upregulation of beta-catenin/T-cell factor complex formation|upregulation of beta-catenin/LEF complex formation|activation of beta-catenin/lymphoid enhancer binding factor complex formation|upregulation of beta-catenin/T-cell factor complex assembly|up regulation of beta-catenin/LEF complex assembly|up regulation of beta-catenin/T-cell factor complex assembly|activation of beta-catenin/T-cell factor complex formation|positive regulation of beta-catenin-TCF complex formation|positive regulation of beta-catenin/T-cell factor complex formation|up regulation of beta-catenin-TCF complex assembly|upregulation of beta-catenin/LEF complex assembly|positive regulation of beta-catenin/LEF complex formation|positive regulation of beta-catenin/lymphoid enhancer binding factor complex formation|upregulation of beta-catenin/lymphoid enhancer binding factor complex formation|up-regulation of beta-catenin-TCF complex assembly|up-regulation of beta-catenin/lymphoid enhancer binding factor complex formation|up regulation of beta-catenin/lymphoid enhancer binding factor complex formation|up-regulation of beta-catenin-TCF complex formation|positive regulation of beta-catenin/T-cell factor complex assembly|up regulation of beta-catenin/LEF complex formation|activation of beta-catenin-TCF complex assembly|positive regulation of beta-catenin/LEF complex assembly|upregulation of beta-catenin-TCF complex formation|up-regulation of beta-catenin/T-cell factor complex formation|up-regulation of beta-catenin/T-cell factor complex assembly						bf	2015-12-17T13:50:53Z						biological_process											owl:Class	
GO:1903525	biolink:NamedThing	regulation of membrane tubulation	Any process that modulates the frequency, rate or extent of membrane tubulation.	got7fsn_ti	regulation of vesicle scission|regulation of plasma membrane tubulation						pm	2014-10-07T12:52:36Z						biological_process											owl:Class	
GO:0032812	biolink:NamedThing	positive regulation of epinephrine secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine.	got7fsn_ti	up-regulation of epinephrine secretion|up regulation of epinephrine secretion|stimulation of epinephrine secretion|activation of epinephrine secretion|upregulation of epinephrine secretion|positive regulation of adrenaline secretion													biological_process											owl:Class	
GO:0001313	biolink:NamedThing	obsolete formation of extrachromosomal circular DNA involved in replicative cell aging	OBSOLETE. Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age.	got7fsn_ti	formation of extrachromosomal circular DNA during replicative cell ageing|assembly of extrachromosomal circular DNA involved in replicative cell aging|formation of extrachromosomal circular DNA during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0090137	biolink:NamedThing	epithelial cell-cell adhesion involved in epithelium migration	The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration.	got7fsn_ti							tb	2009-12-08T01:58:19Z						biological_process											owl:Class	
GO:0043223	biolink:NamedThing	cytoplasmic SCF ubiquitin ligase complex	A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).	got7fsn_ti	cytoplasmic Skp1/Cul1/F-box protein complex|cytoplasmic SCF complex|cytoplasmic cullin complex													cellular_component											owl:Class	
GO:0001814	biolink:NamedThing	negative regulation of antibody-dependent cellular cytotoxicity	Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.	got7fsn_ti	inhibition of antibody-dependent cellular cytotoxicity|down regulation of antibody-dependent cellular cytotoxicity|negative regulation of antibody dependent cell death|downregulation of antibody-dependent cellular cytotoxicity|negative regulation of antibody-dependent cell killing|negative regulation of antibody dependent cell killing|down-regulation of antibody-dependent cellular cytotoxicity|negative regulation of antibody-dependent cell death													biological_process											owl:Class	
GO:0140648	biolink:NamedThing	positive regulation of cell cycle switching, mitotic to meiotic cell cycle	Any process that activates or increases the frequency, rate or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21506					pg	2021-05-25T06:18:49Z						biological_process											owl:Class	
GO:0098575	biolink:NamedThing	lumenal side of lysosomal membrane	The side (leaflet) of the lysosomal membrane that faces the lumen.	got7fsn_ti	internal leaflet of lysosomal membrane|internal side of lysosomal membrane													cellular_component											owl:Class	
GO:1900324	biolink:NamedThing	regulation of maltotriulose transport	Any process that modulates the frequency, rate or extent of maltotriulose transport.	got7fsn_ti							tt	2012-04-06T01:48:06Z						biological_process											owl:Class	
GO:1900402	biolink:NamedThing	obsolete regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process.	got7fsn_ti	regulation of carbohydrate metabolism by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T02:45:27Z		True				biological_process											owl:Class	
GO:0140214	biolink:NamedThing	positive regulation of long-chain fatty acid import into cell	Any process that activates or increases the frequency, rate or extent of long-chain fatty acid import into a cell.	got7fsn_ti							pg	2018-04-10T15:15:03Z						biological_process											owl:Class	
GO:0045662	biolink:NamedThing	negative regulation of myoblast differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti	downregulation of myoblast differentiation|inhibition of myoblast differentiation|down-regulation of myoblast differentiation|down regulation of myoblast differentiation													biological_process											owl:Class	
GO:0016093	biolink:NamedThing	polyprenol metabolic process	The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.	got7fsn_ti	polyprenol metabolism													biological_process											owl:Class	
GO:1990843	biolink:NamedThing	obsolete subsarcolemmal mitochondrion	OBSOLETE. A mitochondrion that occurs adjacent to the sarcolemma in striated muscle cells and responds in distinct ways to physiological triggers.	got7fsn_ti	SS mitochondrion|SSM				This term was obsoleted because it corresponds to mitochondria of specific cell types and this information should be captured as an extension.	GO:0005739	sl	2015-08-31T16:05:14Z		True				cellular_component											owl:Class	
GO:0015832	biolink:NamedThing	obsolete holin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	holin				This term was made obsolete because it represents a class of gene products.	GO:0019835				True				biological_process											owl:Class	
GO:1904640	biolink:NamedThing	response to methionine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.	got7fsn_ti							sl	2015-08-31T17:23:56Z						biological_process											owl:Class	
GO:0070188	biolink:NamedThing	obsolete Stn1-Ten1 complex	OBSOLETE. A nuclear telomere cap complex that is formed by the association of the Stn1 and Ten1 proteins with telomeric DNA; in some species a third protein is present.	got7fsn_ti				GO:1990879	This term was made obsolete because it was inaccurate.					True				cellular_component											owl:Class	
GO:1901852	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process	The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.	got7fsn_ti	coenzyme F0 biosynthetic process|coenzyme F0 anabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin synthesis|coenzyme F0 biosynthesis|7,8-didemethyl-8-hydroxy-5-deazariboflavin formation|coenzyme F0 formation|coenzyme F0 synthesis|7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis|7,8-didemethyl-8-hydroxy-5-deazariboflavin anabolism						yaf	2013-01-28T11:38:41Z						biological_process											owl:Class	
GO:2000683	biolink:NamedThing	regulation of cellular response to X-ray	Any process that modulates the frequency, rate or extent of cellular response to X-ray.	got7fsn_ti	regulation of cellular response to X-ray radiation stimulus						yaf	2011-05-10T01:40:41Z						biological_process											owl:Class	
GO:1901255	biolink:NamedThing	nucleotide-excision repair involved in interstrand cross-link repair	Any nucleotide-excision repair that is involved in interstrand cross-link repair.	got7fsn_ti	NER involved in interstrand cross-link repair|NER involved in ICL repair|nucleotide-excision repair involved in ICL repair						vw	2012-08-09T06:09:50Z						biological_process											owl:Class	
GO:2000511	biolink:NamedThing	regulation of granzyme A production	Any process that modulates the frequency, rate or extent of granzyme A production.	got7fsn_ti							ebc	2011-03-22T10:31:27Z						biological_process											owl:Class	
GO:1990582	biolink:NamedThing	obsolete intracellular membrane-bounded organelle binding	OBSOLETE. The temporary binding of a protein or protein complex to the membrane of an intracellular membrane-bounded organelle.	got7fsn_ti	intracellular membrane-enclosed organelle binding|intracellular membrane-bounded organelle binding				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-12-10T19:37:09Z		True				molecular_function											owl:Class	
GO:0018973	biolink:NamedThing	trinitrotoluene metabolic process	The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.	got7fsn_ti	trinitrotoluene metabolism											UM-BBD_pathwayID:tnt		biological_process											owl:Class	
GO:0009182	biolink:NamedThing	purine deoxyribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:1902997	biolink:NamedThing	negative regulation of neurofibrillary tangle assembly	Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly.	got7fsn_ti	negative regulation of star-shaped neurofibrillary tangle assembly|inhibition of star-shaped neurofibrillary tangle assembly|down regulation of star-shaped neurofibrillary tangle assembly|downregulation of neurofibrillary tangle formation|down regulation of neurofibrillary tangle formation|down-regulation of neurofibrillary tangle formation|down regulation of neurofibrillary tangle assembly|down-regulation of flame-shaped neurofibrillary tangle assembly|downregulation of flame-shaped neurofibrillary tangle assembly|down-regulation of star-shaped neurofibrillary tangle assembly|negative regulation of flame-shaped neurofibrillary tangle formation|inhibition of flame-shaped neurofibrillary tangle formation|downregulation of star-shaped neurofibrillary tangle assembly|negative regulation of flame-shaped neurofibrillary tangle assembly|negative regulation of star-shaped neurofibrillary tangle formation|inhibition of neurofibrillary tangle formation|down-regulation of neurofibrillary tangle assembly|down-regulation of flame-shaped neurofibrillary tangle formation|inhibition of star-shaped neurofibrillary tangle formation|down-regulation of star-shaped neurofibrillary tangle formation|downregulation of star-shaped neurofibrillary tangle formation|down regulation of flame-shaped neurofibrillary tangle formation|inhibition of flame-shaped neurofibrillary tangle assembly|downregulation of neurofibrillary tangle assembly|downregulation of flame-shaped neurofibrillary tangle formation|down regulation of flame-shaped neurofibrillary tangle assembly|negative regulation of neurofibrillary tangle formation|down regulation of star-shaped neurofibrillary tangle formation|inhibition of neurofibrillary tangle assembly						sjp	2014-05-08T15:44:33Z						biological_process											owl:Class	
GO:0098934	biolink:NamedThing	retrograde dendritic transport	The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.	got7fsn_ti														biological_process											owl:Class	
GO:1904223	biolink:NamedThing	regulation of glucuronosyltransferase activity	Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity.	got7fsn_ti	regulation of UDP glucuronic acid transferase activity|regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|regulation of 3-OH androgenic UDPGT activity|regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|regulation of UDP glucuronate-estriol glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|regulation of phenyl-UDP-glucuronosyltransferase activity|regulation of 1-naphthol-UDP-glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|regulation of pnp-UDPGT activity|regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|regulation of 4-nitrophenol UDP-glucuronyltransferase activity|regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|regulation of estriol UDPglucuronosyltransferase activity|regulation of bilirubin glucuronyltransferase activity|regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDPGA transferase activity|regulation of bilirubin monoglucuronide glucuronyltransferase activity|regulation of uridine 5'-diphosphoglucuronyltransferase activity|regulation of p-nitrophenylglucuronosyltransferase activity|regulation of UDPGT activity|regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|regulation of 17-OH steroid UDPGT activity|regulation of p-phenylphenol glucuronyltransferase activity|regulation of PNP-UDPGT|regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|regulation of uridine diphosphate glucuronyltransferase activity|regulation of p-nitrophenol UDP-glucuronyltransferase activity|regulation of p-nitrophenol UDP-glucuronosyltransferase activity|regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|regulation of bilirubin UDP-glucuronosyltransferase activity|regulation of UDP-glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|regulation of uridine diphosphoglucuronosyltransferase activity|regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of uridine diphosphoglucuronyltransferase activity|regulation of GT activity|regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|regulation of UDP glucuronosyltransferase activity|regulation of UDPGA-glucuronyltransferase activity|regulation of bilirubin uridine diphosphoglucuronyltransferase activity|regulation of 1-naphthol glucuronyltransferase activity|regulation of ciramadol UDP-glucuronyltransferase activity|regulation of bilirubin UDPGT activity|regulation of UDP glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|regulation of 4-nitrophenol UDPGT activity|regulation of UDP-glucuronosyltransferase activity|regulation of estrone UDPglucuronosyltransferase activity|regulation of morphine glucuronyltransferase activity|regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity				i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species		rl	2015-05-15T08:44:20Z						biological_process											owl:Class	
GO:0019630	biolink:NamedThing	quinate metabolic process	The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine.	got7fsn_ti	quinic acid metabolism|quinic acid metabolic process|quinate metabolism													biological_process											owl:Class	
GO:0110074	biolink:NamedThing	positive regulation of apical constriction involved in ventral furrow formation	Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation.	got7fsn_ti							kmv	2017-12-06T17:39:00Z						biological_process											owl:Class	
GO:1901602	biolink:NamedThing	dethiobiotin binding	Binding to dethiobiotin.	got7fsn_ti							al	2012-11-08T14:09:14Z						molecular_function											owl:Class	
GO:1900344	biolink:NamedThing	positive regulation of methane biosynthetic process from dimethyl sulfide	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.	got7fsn_ti	up regulation of methane biosynthetic process from dimethyl sulfide|activation of methane biosynthetic process from dimethyl sulfide|upregulation of methane biosynthetic process from dimethyl sulfide|up-regulation of methane biosynthetic process from dimethyl sulfide						tt	2012-04-06T02:06:56Z						biological_process											owl:Class	
GO:0010482	biolink:NamedThing	regulation of epidermal cell division	Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.	got7fsn_ti	regulation of hypodermal cell division													biological_process											owl:Class	
GO:1901376	biolink:NamedThing	organic heteropentacyclic compound metabolic process	The chemical reactions and pathways involving organic heteropentacyclic compound.	got7fsn_ti	organic heteropentacyclic compound metabolism						bf	2012-09-28T12:50:41Z						biological_process											owl:Class	
GO:2000362	biolink:NamedThing	negative regulation of prostaglandin-E synthase activity	Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity.	got7fsn_ti	negative regulation of prostaglandin R-prostaglandin E isomerase activity|negative regulation of endoperoxide isomerase activity|negative regulation of prostaglandin H-E isomerase activity|negative regulation of prostaglandin endoperoxide E isomerase activity|negative regulation of prostaglandin endoperoxide E2 isomerase activity|negative regulation of Prostaglandin-H(2) E-isomerase activity|negative regulation of PGE isomerase activity|negative regulation of prostaglandin-H2 E-isomerase activity|negative regulation of PGH-PGE isomerase activity|negative regulation of PGE2 isomerase activity|negative regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity						bf	2011-02-03T04:05:39Z						biological_process											owl:Class	
GO:0060610	biolink:NamedThing	mesenchymal cell differentiation involved in mammary gland development	The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.	got7fsn_ti	mammary gland mesenchymal cell differentiation						dph	2009-05-15T12:17:06Z						biological_process											owl:Class	
GO:1905610	biolink:NamedThing	regulation of mRNA cap binding	Any process that modulates the frequency, rate or extent of mRNA cap binding.	got7fsn_ti							bc	2016-10-28T11:27:28Z						biological_process											owl:Class	
GO:1904088	biolink:NamedThing	positive regulation of epiboly involved in gastrulation with mouth forming second	Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.	got7fsn_ti	activation of epiboly involved in gastrulation with mouth forming second|upregulation of epiboly involved in gastrulation with mouth forming second|up regulation of epiboly involved in gastrulation with mouth forming second|up-regulation of epiboly involved in gastrulation with mouth forming second						dos	2015-03-25T11:17:47Z						biological_process											owl:Class	
GO:0006118	biolink:NamedThing	obsolete electron transport	OBSOLETE. The transport of electrons from an electron donor to an electron acceptor.	got7fsn_ti	dihydrobiopterin reduction|protein-disulfide reduction|dihydrolipoamide reduction|oxidized glutathione reduction|dihydropteridine reduction|electron transfer|dihydrolipoylprotein reduction|6-phosphofructokinase reduction|other pathways of electron transport|electron transport				This term was made obsolete because it describes a molecular function.	GO:0016491|GO:0022904				True				biological_process											owl:Class	
GO:1990034	biolink:NamedThing	calcium ion export across plasma membrane	The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	calcium ion efflux from cell|calcium ion export from cell						mah	2013-02-07T13:01:29Z						biological_process											owl:Class	
GO:1904281	biolink:NamedThing	positive regulation of transcription by RNA polymerase V	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V.	got7fsn_ti	positive regulation of transcription from RNA pol V promoter|positive regulation of transcription from RNA polymerase V promoter|up-regulation of transcription from RNA polymerase V promoter|up regulation of transcription from RNA pol V promoter|up-regulation of transcription from RNA pol V promoter|up regulation of transcription from RNA polymerase V promoter|upregulation of transcription from RNA pol V promoter|activation of transcription from RNA pol V promoter|upregulation of transcription from RNA polymerase V promoter|activation of transcription from RNA polymerase V promoter						tb	2015-06-03T22:02:00Z						biological_process											owl:Class	
GO:1900498	biolink:NamedThing	negative regulation of butyryl-CoA catabolic process to butanol	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol.	got7fsn_ti	downregulation of butyryl-CoA catabolic process to butanol|inhibition of butyryl-CoA catabolic process to butanol|down-regulation of butyryl-CoA catabolic process to butanol|down regulation of butyryl-CoA catabolism to butanol|down-regulation of butyryl-CoA catabolism to butanol|negative regulation of butyryl-CoA catabolism to butanol|downregulation of butyryl-CoA catabolism to butanol|down regulation of butyryl-CoA catabolic process to butanol|inhibition of butyryl-CoA catabolism to butanol						tt	2012-05-02T03:53:31Z						biological_process											owl:Class	
OIO:http://purl.obolibrary.org/obo/IAO_0000233	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
GO:0106107	biolink:NamedThing	regulation of (R)-mevalonic acid biosynthetic process	Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.	got7fsn_ti							hjd	2018-03-27T14:08:59Z						biological_process											owl:Class	
GO:0038072	biolink:NamedThing	obsolete MAP kinase kinase activity involved in conjugation with cellular fusion	OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.	got7fsn_ti	MAPKK activity involved in conjugation with cellular fusion|MAP2K activity involved in conjugation with cellular fusion				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:31:57Z		True				molecular_function											owl:Class	
GO:1900726	biolink:NamedThing	osmoregulated periplasmic glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan.	got7fsn_ti	osmoregulated periplasmic glucan breakdown|osmoregulated periplasmic glucan degradation|osmoregulated periplasmic glucan catabolism						jl	2012-05-24T03:18:54Z						biological_process											owl:Class	
GO:1902255	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.	got7fsn_ti	positive regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up-regulation of intrinsic apoptotic signaling pathway by p53 class mediator|up-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|activation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|activation of signal transduction by p53 class mediator resulting in induction of apoptosis|upregulation of signal transduction by p53 class mediator resulting in induction of apoptosis|activation of intrinsic apoptotic signaling pathway by p53 class mediator|upregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway by p53 class mediator|positive regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway by p53 class mediator						rl	2013-06-20T19:41:54Z						biological_process											owl:Class	
GO:1904714	biolink:NamedThing	regulation of chaperone-mediated autophagy	Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy.	got7fsn_ti	regulation of CMA						pad	2015-10-06T08:49:02Z						biological_process											owl:Class	
GO:0062113	biolink:NamedThing	early phagosome lumen	The volume enclosed by the membrane of an eary phagosome.	got7fsn_ti	early phagocytic vesicle lumen						dph	2019-02-22T12:58:47Z						cellular_component											owl:Class	
GO:1900284	biolink:NamedThing	positive regulation of cellobiose catabolic process	Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process.	got7fsn_ti	up regulation of cellobiose catabolic process|upregulation of cellobiose catabolic process|up regulation of cellobiose catabolism|activation of cellobiose catabolic process|up-regulation of cellobiose catabolism|upregulation of cellobiose catabolism|positive regulation of cellobiose catabolism|activation of cellobiose catabolism|up-regulation of cellobiose catabolic process						tt	2012-04-05T12:29:09Z						biological_process											owl:Class	
GO:0035948	biolink:NamedThing	obsolete positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of glucose biosynthesis by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by up-regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by up regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by upregulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by up-regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by up regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by activation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by up regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by up-regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by upregulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by positive regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by stimulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by upregulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0070543	biolink:NamedThing	response to linoleic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.	got7fsn_ti	response to linoleate													biological_process											owl:Class	
GO:0005400	biolink:NamedThing	obsolete peroxisomal membrane transporter	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peroxisomal membrane transporter				This term was made obsolete because it contains both component and function information.	GO:0005777|GO:0005215				True				molecular_function											owl:Class	
GO:0000988	biolink:NamedThing	obsolete transcription factor activity, protein binding	OBSOLETE. Binding to a protein or protein complex, to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	transcription factor activity|protein binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0005515|GO:0140110	krc	2010-08-10T04:03:22Z		True				molecular_function											owl:Class	
GO:0007345	biolink:NamedThing	obsolete embryogenesis and morphogenesis	OBSOLETE. Formation and development of an embryo and its organized structures.	got7fsn_ti	embryogenesis and morphogenesis				This term was made obsolete because more appropriate terms were created. Morphogenesis in plants also occurs outside of embryogenesis.	GO:0009653|GO:0009790				True				biological_process											owl:Class	
GO:1902931	biolink:NamedThing	negative regulation of alcohol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.	got7fsn_ti	downregulation of alcohol anabolism|inhibition of alcohol biosynthetic process|negative regulation of alcohol biosynthesis|down regulation of alcohol biosynthetic process|inhibition of alcohol formation|down-regulation of alcohol anabolism|downregulation of alcohol biosynthesis|down-regulation of alcohol biosynthesis|negative regulation of alcohol anabolism|negative regulation of solventogenesis|down regulation of alcohol formation|negative regulation of alcohol synthesis|inhibition of alcohol biosynthesis|down regulation of alcohol biosynthesis|down regulation of alcohol anabolism|inhibition of alcohol anabolism|down regulation of alcohol synthesis|down-regulation of alcohol formation|downregulation of alcohol synthesis|downregulation of alcohol formation|down-regulation of alcohol biosynthetic process|downregulation of alcohol biosynthetic process|down-regulation of alcohol synthesis|negative regulation of alcohol formation|inhibition of alcohol synthesis						tt	2014-04-22T21:55:13Z						biological_process											owl:Class	
GO:0075254	biolink:NamedThing	negative regulation of uredospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.	got7fsn_ti	negative regulation of ureidospore formation													biological_process											owl:Class	
GO:1903227	biolink:NamedThing	xanthosine metabolic process	The chemical reactions and pathways involving xanthosine.	got7fsn_ti	xanthosine metabolism						jl	2014-07-31T09:21:46Z						biological_process											owl:Class	
GO:1900639	biolink:NamedThing	positive regulation of asperfuranone biosynthetic process	Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process.	got7fsn_ti	up-regulation of asperfuranone anabolism|up regulation of asperfuranone anabolism|activation of asperfuranone biosynthesis|positive regulation of asperfuranone formation|upregulation of asperfuranone formation|positive regulation of asperfuranone synthesis|upregulation of asperfuranone anabolism|up regulation of asperfuranone biosynthetic process|up-regulation of asperfuranone formation|up regulation of asperfuranone formation|upregulation of asperfuranone biosynthesis|up-regulation of asperfuranone synthesis|up regulation of asperfuranone biosynthesis|upregulation of asperfuranone biosynthetic process|activation of asperfuranone anabolism|up regulation of asperfuranone synthesis|positive regulation of asperfuranone anabolism|activation of asperfuranone formation|upregulation of asperfuranone synthesis|activation of asperfuranone synthesis|positive regulation of asperfuranone biosynthesis|up-regulation of asperfuranone biosynthesis|activation of asperfuranone biosynthetic process|up-regulation of asperfuranone biosynthetic process						di	2012-05-22T03:50:24Z						biological_process											owl:Class	
GO:0008985	biolink:NamedThing	obsolete pyruvate dehydrogenase (cytochrome) activity	OBSOLETE. Catalysis of the reaction: pyruvate + ferricytochrome b1 + H2O = CO2 + acetate + ferrocytochrome b1.	got7fsn_ti	pyruvate dehydrogenase (cytochrome) activity|pyruvate:ferricytochrome-b1 oxidoreductase activity|pyruvic (cytochrome b1) dehydrogenase activity|pyruvate:ubiquinone-8-oxidoreductase activity			GO:0052737	This term was made obsolete because the EC activity it represents, EC:1.2.2.2, has been deleted.					True				molecular_function											owl:Class	
CHEBI:23824	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052453	biolink:NamedThing	obsolete modulation by organism of symbiont intracellular transport	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont intracellular transport|modulation of symbiont intracellular trafficking				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1905091	biolink:NamedThing	positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.	got7fsn_ti	positive regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|activation of parkin-mediated mitophagy in response to mitochondrial depolarization|upregulation of parkin-mediated mitophagy in response to mitochondrial depolarization|positive regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|up regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|up-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization						pad	2016-03-30T15:34:47Z						biological_process											owl:Class	
GO:1990279	biolink:NamedThing	obsolete negative regulation of MBF transcription factor activity	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor MBF.	got7fsn_ti	negative regulation of MBF transcription factor activity				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-01-29T14:46:52Z		True				biological_process											owl:Class	
GO:0043507	biolink:NamedThing	positive regulation of JUN kinase activity	Any process that activates or increases the frequency, rate or extent of JUN kinase activity.	got7fsn_ti	stimulation of JNK activity|up-regulation of JNK activity|positive regulation of JUNK activity|up regulation of JNK activity|upregulation of JNK activity													biological_process											owl:Class	
GO:0052354	biolink:NamedThing	obsolete catabolism by organism of carbohydrate in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism by organism of carbohydrate in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1902074	biolink:NamedThing	response to salt	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.	got7fsn_ti	response to salinity						mls	2013-04-22T15:41:57Z						biological_process											owl:Class	
GO:1903974	biolink:NamedThing	positive regulation of cellular response to macrophage colony-stimulating factor stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.	got7fsn_ti	activation of cellular response to macrophage colony-stimulating factor|up regulation of cellular response to macrophage colony-stimulating factor stimulus|activation of cellular response to macrophage colony-stimulating factor stimulus|upregulation of cellular response to macrophage colony-stimulating factor|positive regulation of cellular response to macrophage colony-stimulating factor|up-regulation of cellular response to M-CSF stimulus|upregulation of cellular response to macrophage colony-stimulating factor stimulus|upregulation of cellular response to M-CSF stimulus|up-regulation of cellular response to macrophage colony-stimulating factor|up regulation of cellular response to M-CSF stimulus|positive regulation of cellular response to M-CSF stimulus|activation of cellular response to M-CSF stimulus|up-regulation of cellular response to macrophage colony-stimulating factor stimulus|up regulation of cellular response to macrophage colony-stimulating factor						nc	2015-03-02T14:50:25Z						biological_process											owl:Class	
GO:0042856	biolink:NamedThing	eugenol catabolic process	The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.	got7fsn_ti	eugenol degradation|eugenic acid catabolic process|eugenic acid catabolism|4-allyl-2-methoxyphenol catabolism|eugenol catabolism|4-allyl-2-methoxyphenol catabolic process|eugenol breakdown													biological_process											owl:Class	
GO:0032144	biolink:NamedThing	4-aminobutyrate transaminase complex	A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity.	got7fsn_ti	GABA-T complex|GABA transaminase complex|ABAT complex													cellular_component											owl:Class	
GO:0052409	biolink:NamedThing	obsolete metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism by organism of cell wall cellulose in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:1903821	biolink:NamedThing	obsolete detection of stimulus involved in morphogenesis checkpoint	OBSOLETE. Any detection of stimulus that is involved in morphogenesis checkpoint.	got7fsn_ti	perception of stimulus involved in morphogenesis checkpoint|stimulus sensing involved in morphogenesis checkpoint|stimulus sensing involved in septin checkpoint|detection of stimulus involved in septin checkpoint|stimulus detection involved in septin checkpoint|perception of stimulus involved in septin checkpoint|stimulus detection involved in morphogenesis checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		jl	2015-01-19T15:03:59Z		True				biological_process											owl:Class	
GO:0046073	biolink:NamedThing	dTMP metabolic process	The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).	got7fsn_ti	dTMP metabolism													biological_process											owl:Class	
GO:2000376	biolink:NamedThing	positive regulation of oxygen metabolic process	Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.	got7fsn_ti	positive regulation of oxygen metabolism|positive regulation of diatomic oxygen metabolic process						mah	2011-02-11T02:03:52Z						biological_process											owl:Class	
GO:1905911	biolink:NamedThing	positive regulation of dauer entry	Any process that activates or increases the frequency, rate or extent of dauer entry.	got7fsn_ti	up-regulation of dauer entry|up regulation of dauer entry|up regulation of nematode entry into dormancy|upregulation of nematode entry into dormancy|up-regulation of nematode entry into dormancy|activation of nematode entry into dormancy|upregulation of dauer entry|positive regulation of nematode entry into dormancy|activation of dauer entry						hbye	2017-02-06T15:34:20Z						biological_process											owl:Class	
GO:0003732	biolink:NamedThing	obsolete snRNA cap binding	OBSOLETE. Interacting selectively with the cap structure at the 5' end of a small nuclear RNA molecule.	got7fsn_ti	snRNA cap binding				This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to.	GO:0000339				True				molecular_function											owl:Class	
GO:0009687	biolink:NamedThing	abscisic acid metabolic process	The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.	got7fsn_ti	abscisic acid metabolism													biological_process											owl:Class	
GO:0106200	biolink:NamedThing	obsolete translocase activity acting on amio acids and peptides linked to the hydrolysis of a nucleoside triphosphate	OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a nucleoside triphosphate.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:25:56Z		True		EC:7.4.2.-		molecular_function											owl:Class	
GO:1904228	biolink:NamedThing	positive regulation of glycogen synthase activity, transferring glucose-1-phosphate	Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.	got7fsn_ti	up regulation of glycogen synthase activity, transferring glucose-1-phosphate|upregulation of glycogen synthase activity, transferring glucose-1-phosphate|up-regulation of glycogen synthase activity, transferring glucose-1-phosphate|activation of glycogen synthase activity, transferring glucose-1-phosphate						rl	2015-05-15T09:23:20Z						biological_process											owl:Class	
GO:0071591	biolink:NamedThing	nicotinic acid riboside metabolic process	The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.	got7fsn_ti	D-ribosylnicotinic acid metabolic process|nicotinic acid riboside metabolism						mah	2010-01-29T11:50:42Z						biological_process											owl:Class	
GO:0003305	biolink:NamedThing	cell migration involved in heart jogging	The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging.	got7fsn_ti							dph	2009-10-22T11:05:46Z						biological_process											owl:Class	
GO:1901649	biolink:NamedThing	negative regulation of actomyosin contractile ring localization	Any process that stops, prevents or reduces the frequency, rate or extent of actomyosin contractile ring localization.	got7fsn_ti	down-regulation of contractile ring localization involved in cell cycle cytokinesis|negative regulation of contractile ring localization involved in cell cycle cytokinesis|down-regulation of actomyosin contractile ring localization|down regulation of contractile ring localization involved in cell cycle cytokinesis|negative regulation of contractile ring localisation involved in cell cycle cytokinesis|down regulation of actomyosin contractile ring localization|inhibition of contractile ring localization involved in cell cycle cytokinesis|downregulation of contractile ring localization involved in cell cycle cytokinesis|inhibition of contractile ring localisation involved in cell cycle cytokinesis|downregulation of contractile ring localisation involved in cell cycle cytokinesis|down regulation of contractile ring localisation involved in cell cycle cytokinesis|downregulation of actomyosin contractile ring localization|inhibition of actomyosin contractile ring localization|down-regulation of contractile ring localisation involved in cell cycle cytokinesis						vw	2012-11-19T13:42:49Z						biological_process											owl:Class	
GO:0070018	biolink:NamedThing	obsolete transforming growth factor beta type I receptor homodimeric complex	OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers.	got7fsn_ti	TGF-beta type I receptor complex|transforming growth factor beta type I receptor complex|TGF-beta type I receptor dimer|TGFBR1 homodimer	https://github.com/geneontology/go-ontology/issues/12676			This term was made obsolete because it does not represent a physiological complex.					True				cellular_component											owl:Class	
GO:1900069	biolink:NamedThing	regulation of cellular hyperosmotic salinity response	Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.	got7fsn_ti	regulation of cellular response to hyperosmotic salt stress						pr	2012-01-26T02:45:39Z						biological_process											owl:Class	
GO:1901859	biolink:NamedThing	negative regulation of mitochondrial DNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.	got7fsn_ti	inhibition of mtDNA metabolism|down-regulation of mitochondrial DNA metabolism|down regulation of mtDNA metabolic process|down-regulation of mtDNA metabolism|downregulation of mitochondrial DNA metabolism|downregulation of mitochondrial DNA metabolic process|down-regulation of mtDNA metabolic process|negative regulation of mitochondrial DNA metabolism|downregulation of mtDNA metabolism|inhibition of mitochondrial DNA metabolism|downregulation of mtDNA metabolic process|negative regulation of mtDNA metabolic process|inhibition of mtDNA metabolic process|negative regulation of mtDNA metabolism|down-regulation of mitochondrial DNA metabolic process|inhibition of mitochondrial DNA metabolic process|down regulation of mtDNA metabolism|down regulation of mitochondrial DNA metabolism|down regulation of mitochondrial DNA metabolic process						yaf	2013-02-01T10:05:09Z						biological_process											owl:Class	
GO:1900381	biolink:NamedThing	positive regulation of asperthecin biosynthetic process	Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process.	got7fsn_ti	activation of asperthecin biosynthetic process|upregulation of asperthecin synthesis|up-regulation of asperthecin biosynthetic process|up-regulation of asperthecin formation|upregulation of asperthecin formation|positive regulation of asperthecin biosynthesis|upregulation of asperthecin biosynthetic process|up regulation of asperthecin synthesis|upregulation of asperthecin biosynthesis|activation of asperthecin formation|positive regulation of asperthecin synthesis|up regulation of asperthecin formation|activation of asperthecin biosynthesis|positive regulation of asperthecin formation|activation of asperthecin synthesis|up-regulation of asperthecin synthesis|up regulation of asperthecin biosynthesis|up-regulation of asperthecin biosynthesis|up regulation of asperthecin biosynthetic process						di	2012-04-17T01:58:45Z						biological_process											owl:Class	
GO:0004973	biolink:NamedThing	obsolete N-methyl-D-aspartate receptor-associated protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	N-methyl-D-aspartate receptor-associated protein activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005515|GO:0005102				True				molecular_function											owl:Class	
GO:1902484	biolink:NamedThing	Sertoli cell apoptotic process	Any apoptotic process in a Sertoli cell.	got7fsn_ti	Sertoli cell apoptosis						pr	2013-11-06T11:27:34Z						biological_process											owl:Class	
GO:0042129	biolink:NamedThing	regulation of T cell proliferation	Any process that modulates the frequency, rate or extent of T cell proliferation.	got7fsn_ti	regulation of T-cell proliferation|regulation of T-lymphocyte proliferation|regulation of T lymphocyte proliferation													biological_process											owl:Class	
GO:1902383	biolink:NamedThing	11-oxo-beta-amyrin biosynthetic process	The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin.	got7fsn_ti	11-oxo-beta-amyrin synthesis|11-oxo-beta-amyrin anabolism|11-oxo-beta-amyrin biosynthesis|11-oxo-beta-amyrin formation						ms	2013-09-03T12:55:46Z						biological_process											owl:Class	
GO:0120253	biolink:NamedThing	hydrocarbon catabolic process	The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.	got7fsn_ti	hydrocarbon breakdown|hydrocarbon catabolism|hydrocarbon degradation	https://github.com/geneontology/go-ontology/issues/19842					krc	2020-09-02T20:58:57Z						biological_process											owl:Class	
GO:0061880	biolink:NamedThing	regulation of anterograde axonal transport of mitochondrion	Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.	got7fsn_ti	regulation of anterograde axon transport of mitochondria						dph	2017-05-30T14:15:46Z						biological_process											owl:Class	
GO:2000096	biolink:NamedThing	positive regulation of Wnt signaling pathway, planar cell polarity pathway	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.	got7fsn_ti	positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway|positive regulation of non-canonical Wnt signaling pathway|positive regulation of PCP pathway|positive regulation of Wnt-JNK signaling pathway|positive regulation of Wnt receptor signalling pathway, planar cell polarity pathway|positive regulation of Wnt-PCP signaling pathway|positive regulation of Wnt-activated signaling pathway, planar cell polarity pathway						jl	2010-09-08T01:07:42Z						biological_process											owl:Class	
GO:1900383	biolink:NamedThing	regulation of synaptic plasticity by receptor localization to synapse	Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse.	got7fsn_ti	regulation of synaptic plasticity by receptor localisation to synapse						kmv	2012-04-17T04:44:37Z						biological_process											owl:Class	
GO:1901714	biolink:NamedThing	positive regulation of urea catabolic process	Any process that activates or increases the frequency, rate or extent of urea catabolic process.	got7fsn_ti	upregulation of urea degradation|up-regulation of urea catabolism|activation of urea decomposition|up regulation of urea catabolic process|upregulation of urea breakdown|up regulation of urea decomposition|positive regulation of urea decomposition|up regulation of urea breakdown|up-regulation of urea breakdown|positive regulation of urea degradation|up-regulation of urea decomposition|up regulation of urea catabolism|upregulation of urea catabolic process|positive regulation of urea catabolism|activation of urea degradation|activation of urea catabolism|up regulation of urea degradation|activation of urea catabolic process|upregulation of urea catabolism|positive regulation of urea breakdown|up-regulation of urea degradation|activation of urea breakdown|up-regulation of urea catabolic process|upregulation of urea decomposition						mcc	2012-12-19T16:12:18Z						biological_process											owl:Class	
GO:1900909	biolink:NamedThing	negative regulation of olefin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process.	got7fsn_ti	inhibition of olefin metabolism|downregulation of olefin metabolic process|down regulation of olefin metabolic process|inhibition of olefin metabolic process|downregulation of olefin metabolism|down regulation of olefin metabolism|negative regulation of olefin metabolism|down-regulation of olefin metabolic process|down-regulation of olefin metabolism						tt	2012-06-13T04:18:50Z						biological_process											owl:Class	
GO:0018941	biolink:NamedThing	organomercury metabolic process	The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom.	got7fsn_ti	organomercury metabolism											UM-BBD_pathwayID:ogm		biological_process											owl:Class	
GO:0003778	biolink:NamedThing	obsolete dynactin motor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dynactin motor				This term was made obsolete because the dynactin complex is not a motor as such, but does regulate the dynein motor complex.					True				molecular_function											owl:Class	
GO:1902019	biolink:NamedThing	regulation of cilium-dependent cell motility	Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.	got7fsn_ti	regulation of ciliary cell motility|regulation of cilium cell motility						jl	2013-03-27T14:42:38Z						biological_process											owl:Class	
GO:0040018	biolink:NamedThing	positive regulation of multicellular organism growth	Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.	got7fsn_ti	positive regulation of body size|positive regulation of body growth													biological_process											owl:Class	
GO:0001910	biolink:NamedThing	regulation of leukocyte mediated cytotoxicity	Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity.	got7fsn_ti	regulation of leucocyte mediated cytotoxicity|regulation of immune cell mediated cell death|regulation of immune cell mediated cell killing|regulation of immune cell mediated cytotoxicity													biological_process											owl:Class	
GO:1904368	biolink:NamedThing	regulation of sclerenchyma cell differentiation	Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation.	got7fsn_ti							tb	2015-06-17T19:53:00Z						biological_process											owl:Class	
GO:1901130	biolink:NamedThing	gentamycin biosynthetic process	The chemical reactions and pathways resulting in the formation of gentamycin.	got7fsn_ti	gentamycin anabolism|gentamycin formation|gentamycin synthesis|gentamycin biosynthesis						yaf	2012-07-11T03:26:59Z						biological_process											owl:Class	
GO:1904509	biolink:NamedThing	negative regulation of protein localization to basolateral plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane.	got7fsn_ti	downregulation of protein localisation in basolateral plasma membrane|down regulation of protein localization to basolateral plasma membrane|down-regulation of protein localisation in basolateral plasma membrane|down regulation of protein localisation to basolateral plasma membrane|downregulation of protein localization in basolateral plasma membrane|down regulation of protein localisation in basolateral plasma membrane|inhibition of protein localisation to basolateral plasma membrane|negative regulation of protein localization in basolateral plasma membrane|down-regulation of protein localization in basolateral plasma membrane|inhibition of protein localisation in basolateral plasma membrane|inhibition of protein localization to basolateral plasma membrane|downregulation of protein localisation to basolateral plasma membrane|down-regulation of protein localization to basolateral plasma membrane|down regulation of protein localization in basolateral plasma membrane|negative regulation of protein localisation to basolateral plasma membrane|inhibition of protein localization in basolateral plasma membrane|negative regulation of protein localisation in basolateral plasma membrane|down-regulation of protein localisation to basolateral plasma membrane|downregulation of protein localization to basolateral plasma membrane						kmv	2015-07-24T17:56:32Z						biological_process											owl:Class	
GO:1904054	biolink:NamedThing	regulation of cholangiocyte proliferation	Any process that modulates the frequency, rate or extent of cholangiocyte proliferation.	got7fsn_ti	regulation of hepatoblast proliferation						sl	2015-03-18T17:56:14Z						biological_process											owl:Class	
GO:1900332	biolink:NamedThing	positive regulation of methane biosynthetic process from trimethylamine	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine.	got7fsn_ti	up regulation of methane biosynthetic process from trimethylamine|up-regulation of methane biosynthetic process from trimethylamine|upregulation of methane biosynthetic process from trimethylamine|activation of methane biosynthetic process from trimethylamine						tt	2012-04-06T01:53:20Z						biological_process											owl:Class	
GO:0071592	biolink:NamedThing	nicotinic acid riboside biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.	got7fsn_ti	D-ribosylnicotinic acid biosynthetic process|nicotinic acid riboside formation|nicotinic acid riboside biosynthesis|nicotinic acid riboside synthesis|nicotinic acid riboside anabolism						mah	2010-01-29T12:01:25Z						biological_process											owl:Class	
GO:1905237	biolink:NamedThing	response to cyclosporin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.	got7fsn_ti	response to cyclophilin						sl	2016-06-07T21:32:06Z						biological_process											owl:Class	
GO:2000499	biolink:NamedThing	obsolete negative regulation of induction of apoptosis in response to chemical stimulus	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of induction of apoptosis in response to chemical stimulus.	got7fsn_ti	negative regulation of induction of apoptosis in response to chemical stimulus|negative regulation of induction of apoptosis in response to chemical substance				This term was made obsolete because it is ill-defined.		yaf	2011-03-18T02:35:44Z		True				biological_process											owl:Class	
GO:1904164	biolink:NamedThing	obsolete negative regulation of triglyceride homeostasis	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride homeostasis.	got7fsn_ti	down-regulation of triglyceride homeostasis|inhibition of triacylglycerol homeostasis|down-regulation of triacylglycerol homeostasis|negative regulation of triacylglycerol homeostasis|down regulation of triacylglycerol homeostasis|downregulation of triglyceride homeostasis|down regulation of triglyceride homeostasis|inhibition of triglyceride homeostasis|downregulation of triacylglycerol homeostasis				This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2015-04-22T11:04:49Z		True				biological_process											owl:Class	
GO:0033158	biolink:NamedThing	obsolete regulation of protein import into nucleus, translocation	OBSOLETE. Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.	got7fsn_ti	regulation of protein import into cell nucleus, translocation				This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True				biological_process											owl:Class	
GO:0009586	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071635	biolink:NamedThing	negative regulation of transforming growth factor beta production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.	got7fsn_ti	negative regulation of transforming growth factor-beta secretion|negative regulation of transforming growth factor-beta production|negative regulation of TGFbeta production|negative regulation of TGF-B production|negative regulation of TGFB production|negative regulation of TGF-beta production						mah	2010-02-12T10:39:51Z			GO:2001202			biological_process											owl:Class	
GO:1901996	biolink:NamedThing	regulation of indoleacetic acid biosynthetic process via tryptophan	Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.	got7fsn_ti	regulation of IAA biosynthetic process via tryptophan|regulation of indoleacetic acid anabolism via tryptophan|regulation of indoleacetic acid formation via tryptophan|regulation of indoleacetic acid synthesis via tryptophan						tb	2013-03-19T19:14:09Z						biological_process											owl:Class	
GO:1904570	biolink:NamedThing	negative regulation of selenocysteine incorporation	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation.	got7fsn_ti	downregulation of selenocysteine incorporation|inhibition of selenocysteine incorporation|down regulation of selenocysteine incorporation|down-regulation of selenocysteine incorporation						sl	2015-08-19T17:26:44Z						biological_process											owl:Class	
GO:1902002	biolink:NamedThing	obsolete protein phosphorylation involved in cellular protein catabolic process	OBSOLETE. Any protein phosphorylation that is involved in cellular protein catabolic process.	got7fsn_ti	protein amino acid phosphorylation involved in cellular protein catabolism|protein amino acid phosphorylation involved in cellular protein degradation|protein amino acid phosphorylation involved in cellular protein catabolic process|protein phosphorylation involved in cellular protein degradation|protein amino acid phosphorylation involved in cellular protein breakdown|protein phosphorylation involved in cellular protein catabolism|protein phosphorylation involved in cellular protein breakdown	https://github.com/geneontology/go-ontology/issues/14137			This term has been obsoleted because it represents a GO-CAM model.		pr	2013-03-21T10:08:19Z		True				biological_process											owl:Class	
GO:1902982	biolink:NamedThing	DNA strand elongation involved in premeiotic DNA replication	Any DNA strand elongation involved in meiotic cell cycle DNA replication.	got7fsn_ti	DNA strand elongation involved in meiotic cell cycle DNA replication						jl	2014-05-06T20:33:15Z						biological_process											owl:Class	
GO:0051281	biolink:NamedThing	positive regulation of release of sequestered calcium ion into cytosol	Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.	got7fsn_ti	positive regulation of cytosolic release of sequestered calcium ion (Ca2+)|positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|activation of release of sequestered calcium ion into cytosol|positive regulation of cytosolic release of stored calcium ion (Ca2+)|up regulation of release of sequestered calcium ion into cytosol|upregulation of release of sequestered calcium ion into cytosol|up-regulation of release of sequestered calcium ion into cytosol|positive regulation of calcium mobilization|positive regulation of release of stored calcium ion (Ca2+) into cytoplasm|stimulation of release of sequestered calcium ion into cytosol|positive regulation of cytoplasmic release of stored calcium ion (Ca2+)|positive regulation of release of stored calcium ion (Ca2+)|positive regulation of release of sequestered calcium ion into cytoplasm|positive regulation of release of sequestered calcium ion (Ca2+)|positive regulation of calcium ion (Ca2+) mobilization|positive regulation of release of stored calcium ion (Ca2+) into cytosol													biological_process											owl:Class	
GO:1905036	biolink:NamedThing	positive regulation of antifungal innate immune response	Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response.	got7fsn_ti	activation of antifungal innate immune response|upregulation of antifungal innate immune response|up-regulation of antifungal innate immune response|up regulation of antifungal innate immune response						dph	2016-03-07T20:08:26Z						biological_process											owl:Class	
GO:1900361	biolink:NamedThing	negative regulation of pentasaccharide transport	Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport.	got7fsn_ti	down-regulation of pentasaccharide transport|downregulation of pentasaccharide transport|inhibition of pentasaccharide transport|down regulation of pentasaccharide transport						tt	2012-04-06T02:19:36Z						biological_process											owl:Class	
GO:2001147	biolink:NamedThing	camalexin binding	Binding to camalexin.	got7fsn_ti	3-(1,3-thiazol-2-yl)-1H-indole binding						tb	2011-10-19T10:54:19Z						molecular_function											owl:Class	
GO:0098649	biolink:NamedThing	obsolete response to peptidyl-dipeptidase A inhibitor	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidyl-dipeptidase A inhibitor stimulus.	got7fsn_ti	response to ACE inhibitor|response to angiotensin-converting enzyme inhibitor	https://github.com/geneontology/go-ontology/issues/19725			This term was obsoleted because it does not represent a physiological process.					True				biological_process											owl:Class	
GO:0150031	biolink:NamedThing	regulation of protein localization to lysosome	Any process that modulates the frequency, rate or extent of protein localization to lysosome.	got7fsn_ti							bc	2018-02-06T17:07:03Z						biological_process											owl:Class	
GO:0052132	biolink:NamedThing	obsolete positive aerotaxis on or near host	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1904911	biolink:NamedThing	negative regulation of establishment of RNA localization to telomere	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere.	got7fsn_ti	negative regulation of establishment of RNA localisation to telomere|downregulation of establishment of RNA localisation to telomere|inhibition of establishment of RNA localization to telomere|down-regulation of establishment of RNA localization to telomere|down regulation of establishment of RNA localization to telomere|down-regulation of establishment of RNA localisation to telomere|down regulation of establishment of RNA localisation to telomere|inhibition of establishment of RNA localisation to telomere|downregulation of establishment of RNA localization to telomere						rph	2016-01-19T10:34:28Z						biological_process											owl:Class	
GO:2000525	biolink:NamedThing	positive regulation of T cell costimulation	Any process that activates or increases the frequency, rate or extent of T cell costimulation.	got7fsn_ti	positive regulation of T-lymphocyte costimulation|positive regulation of T lymphocyte costimulation|positive regulation of T-cell costimulation|positive regulation of T-cell co-stimulation|positive regulation of T cell co-stimulation						ebc	2011-03-23T10:23:36Z						biological_process											owl:Class	
GO:0052057	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type III secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type III secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0120176	biolink:NamedThing	positive regulation of torso signaling pathway	Any process that activates or increases the frequency, rate or extent of the torso signaling pathway.	got7fsn_ti							krc	2018-06-07T16:52:52Z						biological_process											owl:Class	
GO:0001557	biolink:NamedThing	obsolete metabolic process resulting in cell growth	OBSOLETE. The chemical reactions that occur in living organisms that result in an increase in the mass (size) of a cell.	got7fsn_ti	metabolic process resulting in cell growth				This term was made obsolete as part of the metabolism rearrangements, because it is redundant with other terms.	GO:0016049|GO:0008152				True				biological_process											owl:Class	
GO:1903121	biolink:NamedThing	regulation of TRAIL-activated apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.	got7fsn_ti	regulation of TRAIL-activated extrinsic apoptotic signaling pathway|regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|regulation of TRAIL-induced apoptotic signaling pathway						bf	2014-06-17T12:39:15Z						biological_process											owl:Class	
GO:0075189	biolink:NamedThing	positive regulation of hyphopodium formation	Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of hyphopodium formation on or near host													biological_process											owl:Class	
GO:1900759	biolink:NamedThing	positive regulation of D-amino-acid oxidase activity	Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity.	got7fsn_ti	up regulation of new yellow enzyme|positive regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|upregulation of D-amino-acid oxidase activity|up regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|up regulation of D-amino-acid oxidase activity|positive regulation of new yellow enzyme|positive regulation of L-amino acid:O2 oxidoreductase activity|up regulation of L-amino acid:O2 oxidoreductase activity|activation of D-amino-acid oxidase activity|up-regulation of D-amino-acid oxidase activity|upregulation of L-amino acid:O2 oxidoreductase activity|up-regulation of new yellow enzyme|upregulation of new yellow enzyme|up-regulation of L-amino acid:O2 oxidoreductase activity|up-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|activation of L-amino acid:O2 oxidoreductase activity|upregulation of D-amino-acid:oxygen oxidoreductase (deaminating)|activation of D-amino-acid:oxygen oxidoreductase (deaminating)|activation of new yellow enzyme						pm	2012-05-31T11:24:14Z						biological_process											owl:Class	
GO:0106049	biolink:NamedThing	regulation of cellular response to osmotic stress	Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress.	got7fsn_ti							hjd	2017-08-04T14:53:47Z						biological_process											owl:Class	
GO:0060629	biolink:NamedThing	regulation of homologous chromosome segregation	Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.	got7fsn_ti							dph	2009-05-18T02:41:02Z						biological_process											owl:Class	
GO:0052140	biolink:NamedThing	obsolete positive chemotaxis in host	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive chemotaxis within host	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0019719	biolink:NamedThing	obsolete smooth microsome	OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum and plasma membranes without any adhering ribosomes.	got7fsn_ti	smooth microsome				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005790				True				cellular_component											owl:Class	
GO:0071649	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 5 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.	got7fsn_ti	regulation of RANTES production|regulation of CCL5 production|regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:0051625	biolink:NamedThing	epinephrine uptake	The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	got7fsn_ti	adrenaline reuptake|adrenaline uptake|epinephrine reuptake|epinephrine import													biological_process											owl:Class	
GO:1904608	biolink:NamedThing	response to monosodium L-glutamate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus.	got7fsn_ti							sl	2015-08-27T18:43:08Z						biological_process											owl:Class	
GO:2000409	biolink:NamedThing	positive regulation of T cell extravasation	Any process that activates or increases the frequency, rate or extent of T cell extravasation.	got7fsn_ti	positive regulation of T-cell extravasation|positive regulation of T lymphocyte extravasation|positive regulation of T-lymphocyte extravasation						mah	2011-02-23T10:52:50Z						biological_process											owl:Class	
GO:0001914	biolink:NamedThing	regulation of T cell mediated cytotoxicity	Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity.	got7fsn_ti	regulation of T lymphocyte mediated cytotoxicity|regulation of T-cell mediated cytolysis|regulation of T-cell mediated cell killing|regulation of T-lymphocyte mediated cytotoxicity|regulation of T-cell mediated apoptosis|regulation of T cell mediated cell death|regulation of T cell mediated apoptosis|regulation of T-cell mediated cell death|regulation of T cell mediated cytolysis|regulation of T-cell mediated cytotoxicity|regulation of T cell mediated cell killing													biological_process											owl:Class	
GO:0097469	biolink:NamedThing	obsolete cyclin-dependent protein tyrosine kinase activity	OBSOLETE. Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. This reaction requires the binding of a regulatory cyclin subunit.	got7fsn_ti	cyclin-dependent protein tyrosine kinase activity				This term was made obsolete because it was added in error; the specific activity it refers to has never been observed.		pr	2013-02-19T12:42:11Z		True				molecular_function											owl:Class	
GO:1904695	biolink:NamedThing	positive regulation of vascular associated smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction.	got7fsn_ti	up regulation of vascular smooth muscle contraction|positive regulation of vascular smooth muscle contraction|up-regulation of vascular smooth muscle contraction|upregulation of vascular smooth muscle contraction|activation of vascular smooth muscle contraction						rph	2015-09-29T13:39:14Z						biological_process											owl:Class	
GO:1902242	biolink:NamedThing	copal-8-ol diphosphate(3-) catabolic process	The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-).	got7fsn_ti	copal-8-ol diphosphate(3-) breakdown|copal-8-ol diphosphate(3-) catabolism|copal-8-ol diphosphate(3-) degradation						ms	2013-06-20T09:09:33Z						biological_process											owl:Class	
GO:0045710	biolink:NamedThing	negative regulation of larval salivary gland boundary specification	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism.	got7fsn_ti	downregulation of larval salivary gland determination|down-regulation of larval salivary gland determination|down regulation of larval salivary gland determination|negative regulation of larval salivary gland determination|inhibition of larval salivary gland determination													biological_process											owl:Class	
GO:0090243	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in somitogenesis	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis.	got7fsn_ti	fibroblast growth factor receptor signalling pathway involved in somitogenesis						tb	2010-01-22T10:46:15Z						biological_process											owl:Class	
GO:1905599	biolink:NamedThing	positive regulation of low-density lipoprotein receptor activity	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity.	got7fsn_ti	up-regulation of LDL receptor|activation of LDLR activity|positive regulation of LDL receptor|upregulation of LDLR activity|activation of LDL receptor|up regulation of low-density lipoprotein receptor activity|activation of low-density lipoprotein receptor activity|up-regulation of low-density lipoprotein receptor activity|upregulation of LDL receptor|positive regulation of LDLR activity|upregulation of low-density lipoprotein receptor activity|up regulation of LDLR activity|up regulation of LDL receptor|up-regulation of LDLR activity						nc	2016-10-26T11:53:41Z						biological_process											owl:Class	
GO:1904685	biolink:NamedThing	positive regulation of metalloendopeptidase activity	Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity.	got7fsn_ti	upregulation of metalloendoprotease activity|up regulation of metalloendoproteinase activity|up regulation of metalloendopeptidase activity|positive regulation of metalloendoprotease activity|upregulation of metalloendoproteinase activity|up-regulation of metalloendoprotease activity|upregulation of metalloendopeptidase activity|up-regulation of metalloendopeptidase activity|activation of metalloendopeptidase activity|up-regulation of metalloendoproteinase activity|positive regulation of metalloendoproteinase activity|activation of metalloendoprotease activity|up regulation of metalloendoprotease activity|activation of metalloendoproteinase activity						rph	2015-09-24T11:18:28Z						biological_process											owl:Class	
GO:0070624	biolink:NamedThing	negative regulation of thiamine biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.	got7fsn_ti	downregulation of thiamine biosynthetic process|negative regulation of thiamin biosynthetic process|down regulation of thiamine biosynthetic process|inhibition of thiamine biosynthetic process|down-regulation of thiamine biosynthetic process|negative regulation of thiamine anabolism|negative regulation of thiamine synthesis|negative regulation of thiamine biosynthesis|negative regulation of thiamine formation						mah	2009-05-01T03:20:41Z						biological_process											owl:Class	
GO:0015241	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015040	biolink:NamedThing	obsolete electron transfer flavoprotein, group I	OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway.	got7fsn_ti	electron transfer flavoprotein, group I			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:2000920	biolink:NamedThing	positive regulation of glucuronoarabinoxylan catabolic process	Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process.	got7fsn_ti	positive regulation of glucuronoarabinoxylan catabolism						tt	2011-08-01T12:36:58Z						biological_process											owl:Class	
GO:1900198	biolink:NamedThing	positive regulation of penicillin biosynthetic process	Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process.	got7fsn_ti	up regulation of penicillin synthesis|activation of penicillin synthesis|up-regulation of penicillin biosynthesis|up regulation of penicillin biosynthetic process|upregulation of penicillin synthesis|up regulation of penicillin biosynthesis|upregulation of penicillin biosynthetic process|up-regulation of penicillin anabolism|positive regulation of penicillin synthesis|positive regulation of penicillin anabolism|up-regulation of penicillin biosynthetic process|up regulation of penicillin formation|upregulation of penicillin formation|activation of penicillin biosynthetic process|up-regulation of penicillin synthesis|activation of penicillin biosynthesis|activation of penicillin formation|up-regulation of penicillin formation|up regulation of penicillin anabolism|upregulation of penicillin biosynthesis|positive regulation of penicillin biosynthesis|activation of penicillin anabolism|upregulation of penicillin anabolism|positive regulation of penicillin formation						di	2012-03-20T03:56:52Z						biological_process											owl:Class	
GO:1901622	biolink:NamedThing	positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.	got7fsn_ti	activation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|up regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|up-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|activation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|positive regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|positive regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|activation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|positive regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|up-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|upregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|activation of hh signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning						krc	2012-11-13T20:12:06Z						biological_process											owl:Class	
GO:1900501	biolink:NamedThing	negative regulation of butyryl-CoA catabolic process to butyrate	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.	got7fsn_ti	down-regulation of butyryl-CoA catabolism to butyrate|inhibition of butyryl-CoA catabolism to butyrate|negative regulation of butyryl-CoA catabolism to butyrate|down-regulation of butyryl-CoA catabolic process to butyrate|downregulation of butyryl-CoA catabolism to butyrate|down regulation of butyryl-CoA catabolism to butyrate|inhibition of butyryl-CoA catabolic process to butyrate|down regulation of butyryl-CoA catabolic process to butyrate|downregulation of butyryl-CoA catabolic process to butyrate						tt	2012-05-02T03:56:30Z						biological_process											owl:Class	
GO:0048347	biolink:NamedThing	negative regulation of paraxial mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.	got7fsn_ti	downregulation of paraxial mesodermal cell fate determination|inhibition of paraxial mesodermal cell fate determination|down-regulation of paraxial mesodermal cell fate determination|down regulation of paraxial mesodermal cell fate determination													biological_process											owl:Class	
GO:1902704	biolink:NamedThing	hexose catabolic process to acetone	The chemical reactions and pathways resulting in the breakdown of hexose to acetone.	got7fsn_ti	hexose degradation to acetone|hexose catabolism to acetone|hexose catabolic process to 2-propanone|hexose breakdown to acetone|solventogenesis						tb	2014-02-19T18:43:13Z			GO:1990285			biological_process											owl:Class	
GO:1904078	biolink:NamedThing	positive regulation of estrogen biosynthetic process	Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process.	got7fsn_ti	activation of estrogen synthesis|up regulation of estrogen formation|up regulation of estrogen synthesis|positive regulation of oestrogen biosynthetic process|up-regulation of estrogen formation|up regulation of oestrogen biosynthesis|up-regulation of estrogen synthesis|up-regulation of estrogen biosynthesis|positive regulation of estrogen synthesis|up regulation of estrogen biosynthesis|positive regulation of oestrogen biosynthesis|activation of estrogen biosynthetic process|upregulation of oestrogen biosynthesis|positive regulation of estrogen anabolism|upregulation of estrogen biosynthetic process|upregulation of estrogen synthesis|positive regulation of estrogen biosynthesis|up regulation of estrogen anabolism|up-regulation of estrogen anabolism|up-regulation of estrogen biosynthetic process|upregulation of estrogen anabolism|up-regulation of oestrogen biosynthesis|up regulation of estrogen biosynthetic process|positive regulation of estrogen formation|up regulation of oestrogen biosynthetic process|activation of oestrogen biosynthesis|upregulation of oestrogen biosynthetic process|upregulation of estrogen formation|activation of estrogen anabolism|activation of estrogen formation|activation of estrogen biosynthesis|up-regulation of oestrogen biosynthetic process|activation of oestrogen biosynthetic process|upregulation of estrogen biosynthesis						tb	2015-03-20T16:56:26Z						biological_process											owl:Class	
GO:0061924	biolink:NamedThing	regulation of formation of radial glial scaffolds	Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.	got7fsn_ti	regulation of Bergmann fiber biosynthesis|regulation of radial glial scaffold formation|regulation of Bergmann fiber formation						dph	2017-08-02T16:17:31Z						biological_process											owl:Class	
GO:0050856	biolink:NamedThing	regulation of T cell receptor signaling pathway	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.	got7fsn_ti	regulation of TCR signaling pathway|regulation of T-lymphocyte receptor signaling pathway|regulation of T lymphocyte receptor signalling pathway|regulation of T-lymphocyte receptor signalling pathway|regulation of T lymphocyte receptor signaling pathway|regulation of T-cell receptor signalling pathway|regulation of T-cell receptor signaling pathway													biological_process											owl:Class	
GO:0052227	biolink:NamedThing	obsolete catabolism of substance in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism resulting in the breakdown of substances, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism of substance in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0033602	biolink:NamedThing	negative regulation of dopamine secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.	got7fsn_ti	downregulation of dopamine secretion|down regulation of dopamine secretion|down-regulation of dopamine secretion|inhibition of dopamine secretion													biological_process											owl:Class	
GO:1903079	biolink:NamedThing	obsolete negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape	OBSOLETE. Any negative regulation of protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape.	got7fsn_ti	inhibition of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|downregulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down-regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|downregulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down-regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|negative regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|inhibition of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape				This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2014-05-29T17:42:24Z		True				biological_process											owl:Class	
GO:0140619	biolink:NamedThing	DNA strand exchange activator activity	Binds to and increases a DNA strand exchange activity.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20964					pg	2021-02-26T17:56:46Z						molecular_function											owl:Class	
GO:0052888	biolink:NamedThing	obsolete dihydroorotate oxidase (fumarate) activity	OBSOLETE. Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.	got7fsn_ti	dihydroorotate dehydrogenase activity|dihydroorotate oxidase (fumarate) activity|DHodehase activity|DHOD activity|dihydoorotic acid dehydrogenase activity|DHOdase activity|dihydroorotate oxidase activity				EC has determined that this reaction in fact does not exist and have withdrawn EC:1.3.3.1. Note: If fumarate is not shown to be involved, you may want to consider GO:0004152, dihydroorotate dehydrogenase activity (parent term); if the reaction involves fumarate, then use GO:0052888 dihydroorotate oxidase (fumarate) activity. Details at http://sourceforge.net/p/geneontology/ontology-requests/10770/, RHEA:30059 and EC:1.3.98 removed so as not to conflict with remapping					True		MetaCyc:RXN-9929|KEGG_REACTION:R01867|EC:1.3.98.1		molecular_function											owl:Class	
GO:0002866	biolink:NamedThing	positive regulation of acute inflammatory response to antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.	got7fsn_ti	up-regulation of acute inflammatory response to antigenic stimulus|stimulation of acute inflammatory response to antigenic stimulus|upregulation of acute inflammatory response to antigenic stimulus|activation of acute inflammatory response to antigenic stimulus|up regulation of acute inflammatory response to antigenic stimulus													biological_process											owl:Class	
PR:000007928	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000184	biolink:NamedThing	positive regulation of progesterone biosynthetic process	Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.	got7fsn_ti	positive regulation of progesterone biosynthesis|positive regulation of progesterone anabolism|positive regulation of progesterone synthesis|positive regulation of progesterone formation						dph	2010-10-14T07:36:14Z						biological_process											owl:Class	
GO:0075011	biolink:NamedThing	positive regulation of germ tube formation	Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of germ tube formation on or near host													biological_process											owl:Class	
GO:1902645	biolink:NamedThing	tertiary alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of tertiary alcohol.	got7fsn_ti	tertiary alcohol anabolism|tertiary alcohol biosynthesis|tertiary alcohol formation|tertiary alcohol synthesis						tt	2014-01-21T17:54:02Z						biological_process											owl:Class	
GO:0075064	biolink:NamedThing	obsolete negative regulation invasive hypha growth	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont invasive hypha formation within host|negative regulation of symbiont invasive hypha formation in host	https://github.com/geneontology/go-ontology/issues/19013			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1901979	biolink:NamedThing	regulation of inward rectifier potassium channel activity	Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity.	got7fsn_ti	regulation of Kir channel activity						tb	2013-03-12T18:21:12Z						biological_process											owl:Class	
GO:0000035	biolink:NamedThing	acyl binding	Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.	got7fsn_ti	acyl-CoA or acyl binding													molecular_function											owl:Class	
GO:0009217	biolink:NamedThing	purine deoxyribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside triphosphate degradation|purine deoxyribonucleoside triphosphate breakdown|purine deoxyribonucleoside triphosphate catabolism													biological_process											owl:Class	
GO:1902247	biolink:NamedThing	geranylgeranyl diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate.	got7fsn_ti	geranylgeranyl diphosphate catabolism|geranylgeranyl diphosphate degradation|geranylgeranyl diphosphate breakdown						ms	2013-06-20T09:10:09Z						biological_process											owl:Class	
GO:0006198	biolink:NamedThing	cAMP catabolic process	The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	cyclic AMP catabolism|3',5' cAMP catabolic process|cyclic AMP catabolic process|3',5'-cAMP catabolism|3',5' cAMP catabolism|adenosine 3',5'-cyclophosphate catabolic process|cAMP degradation|cAMP breakdown|cAMP catabolism|3',5'-cAMP catabolic process|adenosine 3',5'-cyclophosphate catabolism													biological_process											owl:Class	
GO:1903155	biolink:NamedThing	obsolete glutathione transmembrane transporter activity involved in glutathione import into cell	OBSOLETE. Any glutathione transmembrane transporter activity that is involved in glutathione import into cell.	got7fsn_ti	glutathione transmembrane transporter activity involved in glutathione uptake|glutathione transmembrane transporter activity involved in glutathione import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:05Z		True				molecular_function											owl:Class	
GO:0045656	biolink:NamedThing	negative regulation of monocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.	got7fsn_ti	downregulation of monocyte differentiation|down-regulation of monocyte differentiation|down regulation of monocyte differentiation|inhibition of monocyte differentiation													biological_process											owl:Class	
GO:1900357	biolink:NamedThing	regulation of nigerotriose transport	Any process that modulates the frequency, rate or extent of nigerotriose transport.	got7fsn_ti							tt	2012-04-06T02:18:06Z						biological_process											owl:Class	
GO:1905867	biolink:NamedThing	epididymis development	The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure.	got7fsn_ti	epididymus development						sl	2017-01-27T00:00:33Z						biological_process											owl:Class	
GO:0003794	biolink:NamedThing	obsolete acute-phase response protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	acute-phase response protein activity				This term was made obsolete because it refers to involvement in a biological process.	GO:0006953				True				molecular_function											owl:Class	
GO:0019461	biolink:NamedThing	glutamine catabolic process to fumarate, using glutamate synthase (NADPH)	The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13).	got7fsn_ti	glutamine degradation to fumarate, using glutamate synthase (NADPH)|glutamine breakdown to fumarate, using glutamate synthase (NADPH)|glutamate catabolic process to fumarate, using glutamate synthase (NADPH)											MetaCyc:GLUTAMINEFUM-PWY		biological_process											owl:Class	
GO:1904465	biolink:NamedThing	negative regulation of matrix metallopeptidase secretion	Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion.	got7fsn_ti	inhibition of matrix metalloproteinase secretion|down regulation of MMP secretion|inhibition of MMP secretion|negative regulation of matrix metalloproteinase secretion|downregulation of matrix metalloproteinase secretion|down-regulation of MMP secretion|down regulation of matrix metallopeptidase secretion|negative regulation of MMP secretion|inhibition of matrix metallopeptidase secretion|down-regulation of matrix metalloproteinase secretion|down-regulation of matrix metallopeptidase secretion|down regulation of matrix metalloproteinase secretion|downregulation of MMP secretion|downregulation of matrix metallopeptidase secretion						sl	2015-07-09T19:46:24Z						biological_process											owl:Class	
GO:0046708	biolink:NamedThing	IDP biosynthetic process	The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate.	got7fsn_ti	IDP formation|IDP anabolism|IDP synthesis|IDP biosynthesis													biological_process											owl:Class	
GO:0070429	biolink:NamedThing	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.	got7fsn_ti	negative regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway|negative regulation of NOD1 signaling pathway													biological_process											owl:Class	
GO:0030820	biolink:NamedThing	obsolete regulation of cAMP catabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	regulation of cyclic AMP catabolism|regulation of 3',5'-cAMP catabolism|regulation of cyclic AMP catabolic process|regulation of 3',5' cAMP catabolic process|regulation of cAMP catabolism|regulation of 3',5' cAMP catabolism|regulation of cAMP degradation|regulation of 3',5'-cAMP catabolic process|regulation of adenosine 3',5'-cyclophosphate catabolic process|regulation of cAMP breakdown|regulation of adenosine 3',5'-cyclophosphate catabolism				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
PR:000001186	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901106	biolink:NamedThing	tetracenomycin C biosynthetic process	The chemical reactions and pathways resulting in the formation of tetracenomycin C.	got7fsn_ti	tetracenomycin C anabolism|tetracenomycin C formation|tetracenomycin C biosynthesis|tetracenomycin C synthesis						yaf	2012-07-11T02:51:03Z						biological_process											owl:Class	
GO:0008845	biolink:NamedThing	obsolete endonuclease VIII activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	endonuclease VIII activity				This term was made obsolete because it represents a gene product.	GO:0004519|GO:0008081|GO:0000703|GO:0019104|GO:0003684|GO:0003906				True				molecular_function											owl:Class	
GO:1904724	biolink:NamedThing	tertiary granule lumen	Any membrane-enclosed lumen that is part of a tertiary granule.	got7fsn_ti	membrane-enclosed lumen of gelatinase granule|tertiary granule membrane-enclosed lumen|gelatinase granule membrane-enclosed lumen|membrane-enclosed lumen of tertiary granule						mec	2015-10-12T12:53:10Z						cellular_component											owl:Class	
GO:2001160	biolink:NamedThing	regulation of histone H3-K79 methylation	Any process that modulates the frequency, rate or extent of histone H3-K79 methylation.	got7fsn_ti	regulation of histone lysine H3 K79 methylation|regulation of histone H3 K79 methylation|regulation of histone H3K79me						se	2011-10-25T10:27:00Z						biological_process											owl:Class	
GO:1902446	biolink:NamedThing	regulation of shade avoidance	Any process that modulates the frequency, rate or extent of shade avoidance.	got7fsn_ti							dhl	2013-10-15T21:04:36Z						biological_process											owl:Class	
GO:0031161	biolink:NamedThing	phosphatidylinositol catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.	got7fsn_ti	PtdIns catabolism|phosphatidylinositol catabolism|phosphatidylinositol degradation|PtdIns catabolic process|phosphatidylinositol breakdown													biological_process											owl:Class	
GO:0097634	biolink:NamedThing	integral component of phagophore assembly site membrane	The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to phagophore assembly site membrane|phagophore assembly site integral membrane protein													cellular_component											owl:Class	
GO:1903746	biolink:NamedThing	positive regulation of pharyngeal pumping	Any process that activates or increases the frequency, rate or extent of pharyngeal pumping.	got7fsn_ti	up-regulation of pharyngeal pumping|up regulation of pumping behavior|positive regulation of pumping behavior|activation of pharyngeal pumping|upregulation of pumping behavior|activation of pumping behavior|up-regulation of pumping behavior|upregulation of pharyngeal pumping|up regulation of pharyngeal pumping						kmv	2014-12-12T17:11:09Z						biological_process											owl:Class	
GO:1902639	biolink:NamedThing	propan-2-ol metabolic process	The chemical reactions and pathways involving propan-2-ol.	got7fsn_ti	Isopropanol metabolic process|Isopropyl alcohol metabolic process|propan-2-ol metabolism						tt	2014-01-21T13:57:13Z						biological_process											owl:Class	
GO:2000285	biolink:NamedThing	obsolete negative regulation of regulation of excitatory postsynaptic membrane potential	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of excitatory postsynaptic membrane potential.	got7fsn_ti	negative regulation of regulation of excitatory postsynaptic membrane potential|negative regulation of EPSP			GO:0090394	This term was made obsolete because it makes no sense and was added in error.		vk	2010-12-12T03:27:21Z		True				biological_process											owl:Class	
GO:0100044	biolink:NamedThing	obsolete negative regulation of cellular hyperosmotic salinity response by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular hyperosmotic salinity response.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0045746	biolink:NamedThing	negative regulation of Notch signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.	got7fsn_ti	inhibition of Notch signaling pathway|negative regulation of N signalling pathway|downregulation of Notch signaling pathway|negative regulation of Notch signalling pathway|down-regulation of Notch signaling pathway|negative regulation of N signaling pathway|down regulation of Notch signaling pathway													biological_process											owl:Class	
GO:1904605	biolink:NamedThing	positive regulation of advanced glycation end-product receptor activity	Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity.	got7fsn_ti	up-regulation of AGE receptor activity|up regulation of RAGE activity|up regulation of AGE receptor activity|up-regulation of advanced glycation end-product receptor activity|upregulation of RAGE activity|positive regulation of RAGE activity|upregulation of AGE receptor activity|positive regulation of AGE receptor activity|activation of RAGE activity|activation of AGE receptor activity|upregulation of advanced glycation end-product receptor activity|up regulation of advanced glycation end-product receptor activity|activation of advanced glycation end-product receptor activity|up-regulation of RAGE activity						krc	2015-08-26T16:25:02Z						biological_process											owl:Class	
GO:1902790	biolink:NamedThing	undecan-2-one metabolic process	The chemical reactions and pathways involving undecan-2-one.	got7fsn_ti	undecan-2-one metabolism						tt	2014-03-22T02:13:01Z						biological_process											owl:Class	
GO:0031456	biolink:NamedThing	glycine betaine biosynthetic process	The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine.	got7fsn_ti	glycine betaine formation|glycine betaine biosynthesis|N-trimethylglycine biosynthetic process|N-trimethylglycine biosynthesis|glycine betaine anabolism|glycine betaine synthesis													biological_process											owl:Class	
GO:0052463	biolink:NamedThing	obsolete modulation by organism of symbiont phytoalexin production	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont phytoalexin production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:2001174	biolink:NamedThing	negative regulation of histone H2B conserved C-terminal lysine ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.	got7fsn_ti	negative regulation of fission yeast H2B K119 ubiquitination|negative regulation of mammalian H2B K120 ubiquitination|negative regulation of budding yeast H2B K123 ubiquitination						se	2011-10-29T06:28:53Z						biological_process											owl:Class	
GO:1904786	biolink:NamedThing	negative regulation of asymmetric protein localization involved in cell fate determination	Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.	got7fsn_ti	down-regulation of asymmetric protein localization involved in cell fate commitment|inhibition of asymmetric protein localisation involved in cell fate determination|downregulation of asymmetric protein localization involved in cell fate commitment|downregulation of asymmetric protein localization resulting in cell fate commitment|negative regulation of asymmetric protein localization resulting in cell fate commitment|inhibition of asymmetric protein localization involved in cell fate determination|downregulation of asymmetric protein localization involved in cell fate determination|down-regulation of asymmetric protein localisation involved in cell fate determination|downregulation of asymmetric protein localisation involved in cell fate determination|down-regulation of asymmetric protein localization resulting in cell fate commitment|downregulation of cell fate commitment, asymmetric protein localization|negative regulation of asymmetric protein localization involved in cell fate commitment|negative regulation of asymmetric protein localisation involved in cell fate determination|inhibition of asymmetric protein localization involved in cell fate commitment|down regulation of asymmetric protein localization involved in cell fate determination|down regulation of asymmetric protein localization resulting in cell fate commitment|down regulation of asymmetric protein localisation involved in cell fate determination|inhibition of cell fate commitment, asymmetric protein localization|down-regulation of cell fate commitment, asymmetric protein localization|negative regulation of cell fate commitment, asymmetric protein localization|inhibition of asymmetric protein localization resulting in cell fate commitment|down-regulation of asymmetric protein localization involved in cell fate determination|down regulation of cell fate commitment, asymmetric protein localization|down regulation of asymmetric protein localization involved in cell fate commitment				wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP)		es	2015-11-03T12:11:13Z						biological_process											owl:Class	
GO:2000074	biolink:NamedThing	regulation of type B pancreatic cell development	Any process that modulates the frequency, rate or extent of pancreatic B cell development.	got7fsn_ti	regulation of pancreatic B cell development|regulation of pancreatic beta cell development						tb	2010-08-27T11:19:37Z						biological_process											owl:Class	
GO:0052214	biolink:NamedThing	obsolete metabolism of substance in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism of substance in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:2000660	biolink:NamedThing	negative regulation of interleukin-1-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway.	got7fsn_ti	negative regulation of IL-1 alpha-mediated signaling pathway|negative regulation of interleukin-1-mediated signalling pathway|negative regulation of interleukin-1 alpha-mediated signaling pathway|negative regulation of interleukin-1 beta-mediated signaling pathway|negative regulation of IL-1-mediated signaling pathway|negative regulation of IL-1 beta-mediated signaling pathway						dph	2011-05-03T07:13:37Z						biological_process											owl:Class	
GO:1900513	biolink:NamedThing	negative regulation of starch utilization system complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly.	got7fsn_ti	down-regulation of SUS complex assembly|negative regulation of assembly of starch utilization system complex|negative regulation of SUS complex assembly|downregulation of SUS complex assembly|down regulation of assembly of starch utilization system complex|inhibition of starch utilization system complex assembly|downregulation of starch utilization system complex assembly|inhibition of assembly of starch utilization system complex|down regulation of SUS complex assembly|down-regulation of starch utilization system complex assembly|inhibition of SUS complex assembly|down-regulation of assembly of starch utilization system complex|downregulation of assembly of starch utilization system complex|down regulation of starch utilization system complex assembly						tt	2012-05-02T04:06:54Z						biological_process											owl:Class	
GO:1902764	biolink:NamedThing	positive regulation of embryonic skeletal joint development	Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development.	got7fsn_ti	up regulation of embryonic skeletal joint development|activation of embryonic skeletal joint development|up-regulation of embryonic skeletal joint development|upregulation of embryonic skeletal joint development						mr	2014-03-07T17:46:13Z						biological_process											owl:Class	
GO:1905961	biolink:NamedThing	protein-cysteine S-palmitoyltransferase complex	A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity.	got7fsn_ti	Palmitoyltransferase ERF2/SHR5 complex|Palmitoyltransferase ERF2-SHR5 complex				An example of this is ERF2 in Saccharomyces cerevisiae (Q06551) in PMID:20851885 (inferred from direct assay)		bhm	2017-02-23T13:33:15Z						cellular_component											owl:Class	
GO:1905478	biolink:NamedThing	regulation of glutamate-ammonia ligase activity	Any process that modulates the frequency, rate or extent of glutamate-ammonia ligase activity.	got7fsn_ti	regulation of L-glutamine synthetase activity|regulation of L-glutamate:ammonia ligase (ADP-forming)|regulation of glutamine synthetase activity|regulation of glutamylhydroxamic synthetase activity						pga	2016-09-22T09:58:34Z						biological_process											owl:Class	
GO:0110150	biolink:NamedThing	negative regulation of biomineralization	Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.	got7fsn_ti	negative regulation of mineralisation|negative regulation of biomineralisation|negative regulation of mineralization|negative regulation of biomineral formation						kmv	2019-06-10T18:12:24Z						biological_process											owl:Class	
GO:1902649	biolink:NamedThing	regulation of histone H2A-H2B dimer displacement	Any process that modulates the frequency, rate or extent of histone H2A-H2B dimer displacement.	got7fsn_ti							di	2014-01-21T18:19:04Z						biological_process											owl:Class	
GO:0032424	biolink:NamedThing	negative regulation of mismatch repair	Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.	got7fsn_ti	inhibition of mismatch repair|down-regulation of mismatch repair|downregulation of mismatch repair|down regulation of mismatch repair													biological_process											owl:Class	
GO:1901881	biolink:NamedThing	positive regulation of protein depolymerization	Any process that activates or increases the frequency, rate or extent of protein depolymerization.	got7fsn_ti	positive regulation of protein polymer catabolism|activation of protein polymer degradation|up-regulation of protein depolymerization|upregulation of protein polymer breakdown|activation of protein polymer catabolic process|upregulation of protein polymer degradation|up-regulation of protein polymer degradation|up regulation of protein depolymerization|up regulation of protein polymer degradation|positive regulation of protein polymer catabolic process|up regulation of protein polymer catabolism|upregulation of protein depolymerization|activation of protein polymer breakdown|up regulation of protein polymer breakdown|activation of protein depolymerization|up-regulation of protein polymer breakdown|up-regulation of protein polymer catabolic process|up-regulation of protein polymer catabolism|up regulation of protein polymer catabolic process|upregulation of protein polymer catabolic process|upregulation of protein polymer catabolism|positive regulation of protein polymer degradation|activation of protein polymer catabolism|positive regulation of protein polymer breakdown						rl	2013-02-06T13:57:32Z						biological_process											owl:Class	
GO:1903943	biolink:NamedThing	regulation of hepatocyte apoptotic process	Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process.	got7fsn_ti	regulation of hepatocyte apoptosis						sl	2015-02-19T12:54:40Z						biological_process											owl:Class	
GO:0070243	biolink:NamedThing	regulation of thymocyte apoptotic process	Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.	got7fsn_ti	regulation of thymocyte apoptosis|regulation of immature T cell apoptosis				Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).									biological_process											owl:Class	
GO:0006806	biolink:NamedThing	obsolete insecticide resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	insecticide resistance			GO:0017085	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:1903935	biolink:NamedThing	response to sodium arsenite	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	got7fsn_ti							sl	2015-02-12T20:54:33Z						biological_process											owl:Class	
GO:2000481	biolink:NamedThing	positive regulation of cAMP-dependent protein kinase activity	Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity.	got7fsn_ti	positive regulation of protein kinase A activity|positive regulation of 3',5' cAMP-dependent protein kinase activity|positive regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|positive regulation of STK22|positive regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|positive regulation of AMPK|positive regulation of PKA C|positive regulation of 3',5'-cAMP-dependent protein kinase activity|positive regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|positive regulation of PKA|positive regulation of cyclic AMP-dependent protein kinase activity						yaf	2011-03-10T11:14:17Z						biological_process											owl:Class	
GO:0075152	biolink:NamedThing	obsolete negative regulation of receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont receptor-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1905054	biolink:NamedThing	calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration	Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.	got7fsn_ti	calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium levels						dos	2016-03-17T12:12:53Z						molecular_function											owl:Class	
GO:0031632	biolink:NamedThing	positive regulation of synaptic vesicle fusion to presynaptic active zone membrane	Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.	got7fsn_ti	up-regulation of synaptic vesicle fusion to presynaptic membrane|up regulation of synaptic vesicle fusion to presynaptic active zone membrane|upregulation of synaptic vesicle fusion to presynaptic membrane|up-regulation of synaptic vesicle fusion to presynaptic active zone membrane|activation of synaptic vesicle fusion to presynaptic membrane|positive regulation of synaptic vesicle fusion to pre-synaptic membrane|negative regulation of synaptic vesicle fusion to presynaptic membrane|stimulation of synaptic vesicle fusion to presynaptic membrane|up regulation of synaptic vesicle fusion to presynaptic membrane													biological_process											owl:Class	
GO:0030189	biolink:NamedThing	obsolete chaperone activator activity	OBSOLETE. Increases the activity of a molecular chaperone.	got7fsn_ti	chaperone activator activity				This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'.	GO:0006457|GO:0051082|GO:0051787				True				molecular_function											owl:Class	
GO:0000227	biolink:NamedThing	oxaloacetate secondary active transmembrane transporter activity	Enables the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	oxaloacetate carrier activity													molecular_function											owl:Class	
GO:0001925	biolink:NamedThing	negative regulation of B-1 B cell differentiation	Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.	got7fsn_ti	negative regulation of B-1 B-cell differentiation|negative regulation of B-1 B cell development|down-regulation of B-1 B cell differentiation|negative regulation of B-1 B lymphocyte differentiation|negative regulation of B-1 B-lymphocyte differentiation|inhibition of B-1 B cell differentiation|downregulation of B-1 B cell differentiation|down regulation of B-1 B cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0032872	biolink:NamedThing	regulation of stress-activated MAPK cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.	got7fsn_ti	regulation of p38 MAPK signaling|regulation of stress-activated MAPK signalling pathway|regulation of stress-activated MAPKKK signalling pathway|regulation of stress-activated MAPKKK signaling pathway|regulation of p38 MAPK signalling|regulation of stress-activated MAPKKK cascade|regulation of stress-activated MAPK signaling pathway													biological_process											owl:Class	
GO:0071658	biolink:NamedThing	regulation of IP-10 production	Any process that modulates the frequency, rate, or extent of production of IP-10.	got7fsn_ti	regulation of CXCL10 production|regulation of chemokine (C-C motif) ligand 10 production						mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:1900008	biolink:NamedThing	obsolete negative regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.	got7fsn_ti	down regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|negative regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|down regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|down regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging|down regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|negative regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|negative regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.		se	2012-01-09T10:44:10Z		True				biological_process											owl:Class	
GO:1990049	biolink:NamedThing	retrograde neuronal dense core vesicle transport	The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.	got7fsn_ti	retrograde dense core granule transport|retrograde dense core granule trafficking						pr	2013-02-19T13:31:44Z						biological_process											owl:Class	
GO:0100015	biolink:NamedThing	obsolete positive regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates inositol biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0032327	biolink:NamedThing	W-molybdopterin cofactor catabolic process	The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.	got7fsn_ti	W-molybdopterin cofactor degradation|W-molybdopterin cofactor breakdown|Moco catabolic process|Moco catabolism|W-molybdopterin cofactor catabolism													biological_process											owl:Class	
GO:1900994	biolink:NamedThing	(-)-secologanin biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-secologanin.	got7fsn_ti	(-)-secologanin anabolism|(-)-secologanin synthesis|(-)-secologanin formation|(-)-secologanin biosynthesis						yaf	2012-06-14T09:51:46Z						biological_process											owl:Class	
GO:0003269	biolink:NamedThing	BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	BMP signalling pathway involved in regulation of secondary heart field cardioblast proliferation|BMP signaling pathway involved in regulation of second heart field cardioblast proliferation						dph	2009-10-15T02:45:28Z						biological_process											owl:Class	
GO:1902183	biolink:NamedThing	regulation of shoot apical meristem development	Any process that modulates the frequency, rate or extent of shoot apical meristem development.	got7fsn_ti	regulation of SAM development|regulation of primary shoot meristem development|regulation of promeristem development						tb	2013-05-31T16:33:55Z						biological_process											owl:Class	
GO:0075147	biolink:NamedThing	obsolete regulation of signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1901244	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter to protect the cell or organism in response to the presence of a fungus.	got7fsn_ti	up regulation of transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of global transcription from Pol II promoter involved in defence response to fungi|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungi|stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|activation of transcription from RNA polymerase II promoter involved in defence response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of global transcription from Pol II promoter involved in defense response to fungus|activation of transcription from RNA polymerase II promoter involved in defense response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|activation of global transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of transcription from Pol II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defence response to fungus|activation of global transcription from RNA polymerase II promoter involved in defense response to fungi|stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from Pol II promoter involved in defense response to fungus|positive regulation of global transcription from Pol II promoter involved in defence response to fungus|up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of transcription from Pol II promoter involved in defense response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|stimulation of transcription from RNA polymerase II promoter involved in defence response to fungi|activation of transcription from RNA polymerase II promoter involved in defence response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|activation of global transcription from RNA polymerase II promoter involved in defence response to fungus|up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungus|activation of transcription from RNA polymerase II promoter involved in defense response to fungi|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of transcription from Pol II promoter involved in defence response to fungi|activation of global transcription from RNA polymerase II promoter involved in defence response to fungi|upregulation of transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of global transcription from Pol II promoter involved in defense response to fungi|stimulation of transcription from RNA polymerase II promoter involved in defense response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungi				This term was obsoleted because it represents a GO-CAM model.	GO:0050832|GO:0045944	kmv	2012-08-07T18:40:02Z		True				biological_process											owl:Class	
GO:0002729	biolink:NamedThing	positive regulation of natural killer cell cytokine production	Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.	got7fsn_ti	up-regulation of natural killer cell cytokine production|upregulation of natural killer cell cytokine production|stimulation of natural killer cell cytokine production|up regulation of natural killer cell cytokine production|positive regulation of NK cell cytokine production|activation of natural killer cell cytokine production													biological_process											owl:Class	
GO:0140334	biolink:NamedThing	lipopolysaccharide localization to cell outer membrane	A process in which a lipopolysaccharide is transported to the cell outer membrane.	got7fsn_ti	LPS localization to cell outer membrane						pg	2019-05-13T12:23:36Z						biological_process											owl:Class	
GO:0062223	biolink:NamedThing	regulation of somatic muscle development	Any process that regulates the rate, frequency or extent of somatic muscle development.	got7fsn_ti							dph	2020-03-13T18:58:37Z						biological_process											owl:Class	
GO:0001615	biolink:NamedThing	obsolete thyrotropin releasing hormone and secretagogue-like receptors activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	thyrotropin releasing hormone and secretagogue-like receptors activity				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True				molecular_function											owl:Class	
GO:2001150	biolink:NamedThing	positive regulation of dipeptide transmembrane transport	Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.	got7fsn_ti	positive regulation of dipeptide membrane transport						kmv	2011-10-21T06:10:03Z						biological_process											owl:Class	
GO:1904706	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.	got7fsn_ti	down-regulation of vascular smooth muscle cell proliferation|downregulation of vascular smooth muscle cell proliferation|negative regulation of vascular smooth muscle cell proliferation|down regulation of vascular smooth muscle cell proliferation|inhibition of VSMC proliferation|down-regulation of VSMC proliferation|negative regulation of VSMC proliferation|down regulation of VSMC proliferation|downregulation of VSMC proliferation|inhibition of vascular smooth muscle cell proliferation						sl	2015-10-01T16:05:26Z						biological_process											owl:Class	
GO:0005066	biolink:NamedThing	obsolete transmembrane receptor protein tyrosine kinase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transmembrane receptor protein tyrosine kinase signalling protein activity|transmembrane receptor protein tyrosine kinase signaling protein activity				This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556|GO:0007169				True				molecular_function											owl:Class	
GO:0034031	biolink:NamedThing	ribonucleoside bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	ribonucleoside bisphosphate catabolism|ribonucleoside bisphosphate breakdown|ribonucleoside bisphosphate degradation													biological_process											owl:Class	
GO:0007557	biolink:NamedThing	regulation of juvenile hormone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.	got7fsn_ti	regulation of juvenile hormone anabolism|regulation of juvenile hormone formation|regulation of juvenile hormone biosynthesis|regulation of juvenile hormone synthesis													biological_process											owl:Class	
GO:0046442	biolink:NamedThing	aerobactin metabolic process	The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.	got7fsn_ti	aerobactin metabolism													biological_process											owl:Class	
CHEBI:32627	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120272	biolink:NamedThing	positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18757					krc	2020-10-08T21:09:03Z						biological_process											owl:Class	
GO:1905561	biolink:NamedThing	positive regulation of kinetochore assembly	Any process that activates or increases the frequency, rate or extent of kinetochore assembly.	got7fsn_ti	activation of centromere and kinetochore complex maturation|positive regulation of kinetochore formation|up-regulation of kinetochore formation|upregulation of kinetochore formation|up-regulation of chromosome-kinetochore attachment|up regulation of centromere and kinetochore complex maturation|up regulation of kinetochore formation|activation of centromere/kinetochore complex maturation|up-regulation of kinetochore assembly|upregulation of centromere and kinetochore complex maturation|upregulation of chromosome-kinetochore attachment|up regulation of kinetochore assembly|activation of kinetochore assembly|up regulation of chromosome-kinetochore attachment|activation of kinetochore formation|positive regulation of chromosome-kinetochore attachment|up-regulation of centromere and kinetochore complex maturation|upregulation of kinetochore assembly|upregulation of centromere/kinetochore complex maturation|activation of chromosome-kinetochore attachment|positive regulation of centromere and kinetochore complex maturation|up regulation of centromere/kinetochore complex maturation|positive regulation of centromere/kinetochore complex maturation|up-regulation of centromere/kinetochore complex maturation						hbye	2016-10-14T13:47:45Z						biological_process											owl:Class	
GO:0010848	biolink:NamedThing	regulation of chromatin disassembly	Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins.	got7fsn_ti														biological_process											owl:Class	
GO:0061974	biolink:NamedThing	perichondral bone morphogenesis	The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone.	got7fsn_ti							dph	2018-02-12T18:26:10Z						biological_process											owl:Class	
GO:1903545	biolink:NamedThing	cellular response to butyrate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.	got7fsn_ti							mr	2014-10-17T13:57:35Z						biological_process											owl:Class	
GO:0036272	biolink:NamedThing	response to gemcitabine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.	got7fsn_ti	response to 2'-deoxy-2',2'-difluorocytidine|response to 2',2'-difluorodeoxycytidine				Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T01:36:03Z						biological_process											owl:Class	
GO:2000959	biolink:NamedThing	positive regulation of cyclodextrin catabolic process	Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process.	got7fsn_ti	positive regulation of cyclodextrin catabolism						tt	2011-08-01T02:24:06Z						biological_process											owl:Class	
GO:1901618	biolink:NamedThing	organic hydroxy compound transmembrane transporter activity	Enables the transfer of organic hydroxy compound from one side of a membrane to the other.	got7fsn_ti							pr	2012-11-13T12:59:01Z						molecular_function											owl:Class	
GO:0002229	biolink:NamedThing	defense response to oomycetes	Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.	got7fsn_ti														biological_process											owl:Class	
GO:1900371	biolink:NamedThing	regulation of purine nucleotide biosynthetic process	Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.	got7fsn_ti	regulation of purine nucleotide biosynthesis|regulation of purine nucleotide synthesis|regulation of purine nucleotide anabolism|regulation of purine nucleotide formation						krc	2012-04-17T12:32:07Z						biological_process											owl:Class	
GO:0006155	biolink:NamedThing	obsolete adenosine deaminase reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	adenosine deaminase reaction			GO:0004000	This term was made obsolete because it represents a molecular function.					True				biological_process											owl:Class	
GO:0032651	biolink:NamedThing	regulation of interleukin-1 beta production	Any process that modulates the frequency, rate, or extent of interleukin-1 beta production.	got7fsn_ti	regulation of IL-1 beta production|regulation of interleukin-1 beta secretion|regulation of interleukin-1 beta biosynthetic process										GO:0050706|GO:0050722			biological_process											owl:Class	
GO:0060967	biolink:NamedThing	negative regulation of gene silencing by RNA	Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.	got7fsn_ti							dph	2009-10-05T03:21:05Z						biological_process											owl:Class	
GO:0032711	biolink:NamedThing	negative regulation of interleukin-27 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production.	got7fsn_ti	inhibition of interleukin-27 production|down regulation of interleukin-27 production|downregulation of interleukin-27 production|negative regulation of interleukin-27 biosynthetic process|negative regulation of IL-27 production|down-regulation of interleukin-27 production										GO:0045535			biological_process											owl:Class	
GO:1903134	biolink:NamedThing	obsolete trehalose catabolic process involved in cellular response to stress	OBSOLETE. Any trehalose catabolic process that is involved in cellular response to stress.	got7fsn_ti	trehalose degradation involved in cellular response to stress|mykose catabolism involved in cellular response to stress|trehalose breakdown involved in cellular response to stress|trehalose catabolism involved in cellular response to stress|mycose catabolic process involved in cellular response to stress|mykose catabolic process involved in cellular response to stress|mycose catabolism involved in cellular response to stress	https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.		al	2014-06-25T22:28:34Z		True				biological_process											owl:Class	
GO:0097235	biolink:NamedThing	obsolete positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		pr	2012-02-01T05:07:12Z		True				biological_process											owl:Class	
PR:000008534	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097335	biolink:NamedThing	response to quetiapine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.	got7fsn_ti							pr	2012-06-12T11:03:22Z						biological_process											owl:Class	
CHEBI:17368	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018307	biolink:NamedThing	obsolete enzyme active site formation	OBSOLETE. The modification of part of an enzyme to form the active site.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see https://en.wikipedia.org/wiki/Active_site#Mechanisms_involved_in_Catalytic_process.					True				biological_process											owl:Class	
GO:0000187	biolink:NamedThing	obsolete activation of MAPK activity	OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase (MAPK).	got7fsn_ti	activation of MAP kinase|MAPK activation|activation of MAPK activity during sporulation	https://github.com/geneontology/go-ontology/issues/21307			This term was obsoleted because it represents a molecular function.	GO:0043539|GO:0000165				True				biological_process											owl:Class	
GO:0014727	biolink:NamedThing	positive regulation of extraocular skeletal muscle development	Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	got7fsn_ti														biological_process											owl:Class	
GO:1902240	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.	got7fsn_ti	up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|activation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator						pr	2013-06-19T14:00:44Z						biological_process											owl:Class	
GO:1902051	biolink:NamedThing	(25S)-Delta(4)-dafachronate binding	Binding to (25S)-Delta(4)-dafachronate.	got7fsn_ti							ab	2013-04-11T08:33:41Z						molecular_function											owl:Class	
GO:0042376	biolink:NamedThing	phylloquinone catabolic process	The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.	got7fsn_ti	phytonadione catabolism|phytonadione catabolic process|vitamin K1 catabolic process|phylloquinone catabolism|phytomenadione catabolism|phylloquinone breakdown|phytomenadione catabolic process|phytylmenaquinone catabolic process|vitamin K1 catabolism|phytylmenaquinone catabolism|phylloquinone degradation													biological_process											owl:Class	
GO:1903841	biolink:NamedThing	cellular response to arsenite(3-)	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.	got7fsn_ti							mr	2015-01-22T19:49:35Z						biological_process											owl:Class	
GO:0046104	biolink:NamedThing	thymidine metabolic process	The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.	got7fsn_ti	deoxyribosylthymine metabolism|deoxyribosylthymine metabolic process|thymidine metabolism													biological_process											owl:Class	
GO:0072096	biolink:NamedThing	negative regulation of branch elongation involved in ureteric bud branching	Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.	got7fsn_ti							mah	2010-02-10T01:52:09Z						biological_process											owl:Class	
GO:0045949	biolink:NamedThing	positive regulation of phosphorus utilization	Any process that activates or increases the frequency, rate or extent of phosphorus utilization.	got7fsn_ti	up-regulation of phosphorus utilization|activation of phosphorus utilization|upregulation of phosphorus utilization|stimulation of phosphorus utilization|up regulation of phosphorus utilization													biological_process											owl:Class	
GO:0061427	biolink:NamedThing	obsolete negative regulation of ceramide biosynthetic process by negative regulation of transcription from RNA Polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter and stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		dph	2012-02-02T01:30:41Z		True				biological_process											owl:Class	
GO:0048746	biolink:NamedThing	obsolete smooth muscle fiber development	OBSOLETE. The process whose specific outcome is the progression of smooth muscle fiber over time, from its formation to the mature structure.	got7fsn_ti	smooth muscle fiber development|smooth muscle fibre development				This term was made obsolete because smooth muscle does not have fibers.					True				biological_process											owl:Class	
GO:0098916	biolink:NamedThing	anterograde trans-synaptic signaling	Cell-cell signaling from pre to post-synapse, across the synaptic cleft.	got7fsn_ti														biological_process											owl:Class	
GO:1900650	biolink:NamedThing	negative regulation of dehydroaustinol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process.	got7fsn_ti	down-regulation of dehydroaustinol biosynthetic process|inhibition of dehydroaustinol formation|downregulation of dehydroaustinol biosynthetic process|down-regulation of dehydroaustinol synthesis|down-regulation of dehydroaustinol formation|negative regulation of dehydroaustinol synthesis|negative regulation of dehydroaustinol biosynthesis|downregulation of dehydroaustinol anabolism|downregulation of dehydroaustinol formation|downregulation of dehydroaustinol biosynthesis|negative regulation of dehydroaustinol anabolism|inhibition of dehydroaustinol synthesis|down regulation of dehydroaustinol synthesis|inhibition of dehydroaustinol biosynthesis|down-regulation of dehydroaustinol biosynthesis|inhibition of dehydroaustinol anabolism|down regulation of dehydroaustinol biosynthesis|negative regulation of dehydroaustinol formation|down regulation of dehydroaustinol biosynthetic process|inhibition of dehydroaustinol biosynthetic process|down-regulation of dehydroaustinol anabolism|down regulation of dehydroaustinol anabolism|downregulation of dehydroaustinol synthesis|down regulation of dehydroaustinol formation						di	2012-05-22T04:06:22Z						biological_process											owl:Class	
GO:0008144	biolink:NamedThing	obsolete drug binding	OBSOLETE. Binding to a drug, a naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism;typically used in the diagnosis, prevention, or treatment of disease.	got7fsn_ti					It is not meaningful to describe a molecular function by what role a compound may be used for at some times.					True				molecular_function											owl:Class	
GO:1901489	biolink:NamedThing	obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process in response to decreased oxygen levels	OBSOLETE. Negative regulation of transcription factor catabolism in response to decreased oxygen levels, which results in positive regulation of the SREBP signaling pathway.	got7fsn_ti	positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation, in response to decreased oxygen|positive regulation of SREBP signaling by negative regulation of transcription factor catabolism at low oxygen levels|positive regulation of SREBP-mediated signaling pathway in absence of oxygen by negative regulation of transcription factor catabolic process|positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling by inhibition of SREBP degradation in response to decreased oxygen levels				The reason for obsoletion is that this term should be represented by a GO-CAM model.		bf	2012-10-09T08:23:50Z		True				biological_process											owl:Class	
GO:0015176	biolink:NamedThing	obsolete holin	OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases.	got7fsn_ti	holin				This term was made obsolete because it represents a class of gene products.	GO:0019835				True				molecular_function											owl:Class	
GO:2000549	biolink:NamedThing	positive regulation of dendritic cell dendrite assembly	Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly.	got7fsn_ti	positive regulation of dendritic extension						ebc	2011-04-03T07:22:06Z						biological_process											owl:Class	
GO:1902784	biolink:NamedThing	response to undecane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.	got7fsn_ti							tt	2014-03-21T13:39:06Z						biological_process											owl:Class	
GO:1902992	biolink:NamedThing	negative regulation of amyloid precursor protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process.	got7fsn_ti	downregulation of amyloid precursor protein degradation|downregulation of amyloid precursor protein catabolic process|down regulation of APP catabolic process|downregulation of APP catabolic process|negative regulation of amyloid precursor protein breakdown|inhibition of amyloid precursor protein degradation|down regulation of APP catabolism|down-regulation of amyloid precursor protein degradation|inhibition of amyloid precursor protein catabolic process|down regulation of amyloid precursor protein degradation|down-regulation of APP catabolic process|downregulation of amyloid precursor protein catabolism|down regulation of amyloid precursor protein catabolic process|downregulation of amyloid precursor protein breakdown|downregulation of APP catabolism|inhibition of APP catabolic process|down regulation of amyloid precursor protein breakdown|down-regulation of amyloid precursor protein breakdown|down-regulation of amyloid precursor protein catabolic process|negative regulation of amyloid precursor protein degradation|inhibition of APP catabolism|down regulation of amyloid precursor protein catabolism|down-regulation of APP catabolism|negative regulation of amyloid precursor protein catabolism|inhibition of amyloid precursor protein catabolism|inhibition of amyloid precursor protein breakdown|down-regulation of amyloid precursor protein catabolism|negative regulation of APP catabolic process|negative regulation of APP catabolism						rl	2014-05-08T14:21:10Z						biological_process											owl:Class	
GO:0070405	biolink:NamedThing	ammonium ion binding	Binding to ammonium ions (NH4+).	got7fsn_ti	ammonium binding													molecular_function											owl:Class	
GO:0045568	biolink:NamedThing	obsolete positive regulation of TRAIL receptor 2 biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.	got7fsn_ti	positive regulation of TRAIL receptor 2 biosynthesis|upregulation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 synthesis|positive regulation of TRAIL receptor 2 formation|up-regulation of TRAIL receptor 2 biosynthetic process|stimulation of TRAIL receptor 2 biosynthetic process|activation of TRAIL receptor 2 biosynthetic process|up regulation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 anabolism	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1904921	biolink:NamedThing	obsolete negative regulation of MAPK cascade involved in axon regeneration	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in axon regeneration.	got7fsn_ti	down regulation of MAPKKK cascade involved in axon regeneration|inhibition of MAPK cascade involved in axon regeneration|down-regulation of MAPKKK cascade involved in axon regeneration|down-regulation of MAPK signal transduction involved in axon regeneration|down regulation of MAP kinase kinase kinase cascade involved in axon regeneration|negative regulation of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of MAPK signalling involved in axon regeneration|down regulation of MAPK signalling involved in axon regeneration|inhibition of MAPK signaling involved in axon regeneration|downregulation of mitogen-activated protein kinase cascade involved in axon regeneration|down regulation of mitogen-activated protein kinase cascade involved in axon regeneration|inhibition of MAPKKK cascade involved in axon regeneration|down-regulation of MAPK cascade involved in axon regeneration|down-regulation of MAP kinase kinase kinase cascade involved in axon regeneration|negative regulation of mitogen-activated protein kinase cascade involved in axon regeneration|inhibition of MAP kinase cascade involved in axon regeneration|down-regulation of mitogen-activated protein kinase cascade involved in axon regeneration|downregulation of MAPK signalling involved in axon regeneration|down regulation of MAP kinase cascade involved in axon regeneration|downregulation of MAPK signaling involved in axon regeneration|negative regulation of MAPKKK cascade involved in axon regeneration|inhibition of mitogen-activated protein kinase cascade involved in axon regeneration|down-regulation of ERK/MAPK cascade involved in axon regeneration|down-regulation of MAPK signalling involved in axon regeneration|down regulation of MAPKKK cascade during sporulation involved in axon regeneration|inhibition of MAPK signal transduction involved in axon regeneration|down-regulation of MAPKKK cascade during sporulation involved in axon regeneration|downregulation of MAPKKK cascade involved in axon regeneration|down regulation of ERK/MAPK cascade involved in axon regeneration|inhibition of MAPK signalling involved in axon regeneration|down-regulation of MAPK signaling involved in axon regeneration|negative regulation of MAP kinase cascade involved in axon regeneration|downregulation of MAPK cascade involved in axon regeneration|downregulation of MAP kinase kinase kinase cascade involved in axon regeneration|down regulation of MAPK signaling involved in axon regeneration|negative regulation of MAP kinase kinase kinase cascade involved in axon regeneration|inhibition of ERK/MAPK cascade involved in axon regeneration|negative regulation of ERK/MAPK cascade involved in axon regeneration|downregulation of MAP kinase cascade involved in axon regeneration|downregulation of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of MAPK signal transduction involved in axon regeneration|down regulation of MAPK cascade involved in axon regeneration|inhibition of MAPKKK cascade during sporulation involved in axon regeneration|negative regulation of MAPK signaling involved in axon regeneration|downregulation of MAPK signal transduction involved in axon regeneration|down-regulation of MAP kinase cascade involved in axon regeneration|downregulation of ERK/MAPK cascade involved in axon regeneration|down regulation of MAPK signal transduction involved in axon regeneration|inhibition of MAP kinase kinase kinase cascade involved in axon regeneration	https://github.com/geneontology/go-ontology/issues/14323			This term was obsoleted because it represents a GO-CAM model.		kmv	2016-01-25T17:03:42Z		True				biological_process											owl:Class	
GO:0019370	biolink:NamedThing	leukotriene biosynthetic process	The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.	got7fsn_ti	leukotriene anabolism|leukotriene biosynthesis|leukotriene formation|leukotriene synthesis											Wikipedia:Leukotriene#Leukotriene_synthesis		biological_process											owl:Class	
GO:1905107	biolink:NamedThing	obsolete cellular response to Dizocilpine	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-04-04T20:27:01Z		True				biological_process											owl:Class	
GO:0003805	biolink:NamedThing	obsolete coagulation factor XIa activity	OBSOLETE. Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa.	got7fsn_ti	activated blood-coagulation factor XI|blood-coagulation factor XIa|plasma thromboplastin antecedent activity|coagulation factor XIa activity|activated plasma thromboplastin antecedent|blood coagulation factor XI activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:2000171	biolink:NamedThing	negative regulation of dendrite development	Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.	got7fsn_ti							rl	2010-10-07T10:53:15Z						biological_process											owl:Class	
GO:0098679	biolink:NamedThing	obsolete regulation of carbohydrate catabolic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate catabloism.	got7fsn_ti	regulation of carbohydrate catabolism by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dos	2017-01-31T14:46:21Z		True				biological_process											owl:Class	
GO:1904316	biolink:NamedThing	response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.	got7fsn_ti	response to PAF|response to platelet-activating factor						sl	2015-06-10T18:10:17Z						biological_process											owl:Class	
GO:0016944	biolink:NamedThing	obsolete RNA polymerase II transcription elongation factor activity	OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase II following transcription initiation.	got7fsn_ti	Pol II transcription elongation factor activity|RNA polymerase II transcription elongation factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006368				True				molecular_function											owl:Class	
GO:0061509	biolink:NamedThing	asymmetric protein localization to old mitotic spindle pole body	Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically.	got7fsn_ti							dph	2013-02-21T13:49:26Z						biological_process											owl:Class	
GO:0061489	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017139	biolink:NamedThing	obsolete arsenate sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	arsenate sensitivity/resistance			GO:0046685	This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0016463	biolink:NamedThing	P-type zinc transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out).	got7fsn_ti	Zn(2+)-exporting ATPase activity|zinc transmembrane transporter activity, phosphorylative mechanism|ATP phosphohydrolase (Zn2+-exporting)|zinc exporting ATPase activity|zinc-translocating P-type ATPase activity|Zn2+-exporting ATPase activity|P(1B)-type ATPase activity|P1B-type ATPase activity|zinc-exporting ATPase activity											RHEA:20621|MetaCyc:3.6.3.5-RXN|EC:7.2.2.12		molecular_function											owl:Class	
GO:1904315	biolink:NamedThing	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.	got7fsn_ti	ionotropic neurotransmitter receptor activity involved in regulation of post-synaptic membrane potential|ionotropic neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential						dos	2015-06-10T18:02:07Z						molecular_function											owl:Class	
GO:1905814	biolink:NamedThing	positive regulation of motor neuron axon guidance	Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance.	got7fsn_ti	up regulation of motor axon guidance|upregulation of motoneuron axon guidance|activation of motoneuron axon guidance|up regulation of motor neuron axon guidance|up regulation of motoneuron axon guidance|activation of motor axon guidance|activation of motor axon pathfinding|positive regulation of motoneuron axon guidance|up regulation of motor axon pathfinding|up-regulation of motor axon pathfinding|upregulation of motor axon pathfinding|positive regulation of motor axon guidance|upregulation of motor neuron axon guidance|up-regulation of motoneuron axon guidance|activation of motor neuron axon guidance|positive regulation of motor axon pathfinding|up-regulation of motor axon guidance|upregulation of motor axon guidance|up-regulation of motor neuron axon guidance						hbye	2017-01-12T13:25:31Z						biological_process											owl:Class	
GO:2001061	biolink:NamedThing	D-glycero-D-manno-heptose 7-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate.	got7fsn_ti	D-glycero-D-manno-heptose 7-phosphate biosynthesis						jl	2011-09-09T03:29:08Z				UniPathway:UPA00041		biological_process											owl:Class	
GO:1904453	biolink:NamedThing	positive regulation of potassium:proton exchanging ATPase activity	Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.	got7fsn_ti	positive regulation of (K+ + H+)-ATPase activity|activation of H,K-ATPase activity|activation of H+-K+-ATPase activity|up regulation of (K+ + H+)-ATPase activity|activation of gastric H(+)/K(+) ATPase activity|up regulation of H+/K+-exchanging ATPase activity|upregulation of H+/K+-exchanging ATPase activity|up regulation of H(+)/K(+)-exchanging ATPase activity|upregulation of hydrogen:potassium-exchanging ATPase activity|positive regulation of H,K-ATPase activity|upregulation of H+-K+-ATPase activity|positive regulation of gastric H(+)/K(+) ATPase activity|up-regulation of hydrogen:potassium exchanging ATPase activity|positive regulation of hydrogen/potassium-exchanging ATPase activity|activation of (K+ + H+)-ATPase activity|upregulation of H(+)/K(+)-exchanging ATPase activity|up-regulation of gastric H(+)/K(+) ATPase activity|activation of H+/K+-ATPase activity|positive regulation of hydrogen:potassium-exchanging ATPase activity|up regulation of H+/K+-ATPase activity|activation of hydrogen:potassium exchanging ATPase activity|activation of ATP phosphohydrolase (H+/K+-exchanging)|up regulation of hydrogen/potassium-exchanging ATPase activity|up regulation of H,K-ATPase activity|up regulation of H(+)/K(+)-ATPase activity|upregulation of hydrogen/potassium-exchanging ATPase activity|up-regulation of H(+)/K(+)-exchanging ATPase activity|up-regulation of H+-K+-ATPase activity|up-regulation of H(+)/K(+)-ATPase activity|up regulation of ATP phosphohydrolase (H+/K+-exchanging)|up regulation of gastric H+/K+ ATPase|upregulation of H(+)/K(+)-ATPase activity|activation of H(+)/K(+)-exchanging ATPase activity|up-regulation of gastric H+/K+ ATPase|up regulation of hydrogen:potassium exchanging ATPase activity|up-regulation of ATP phosphohydrolase (H+/K+-exchanging)|upregulation of (K+ + H+)-ATPase activity|up-regulation of H+/K+-ATPase activity|up regulation of gastric H(+)/K(+) ATPase activity|activation of gastric H+/K+ ATPase|up-regulation of hydrogen/potassium-exchanging ATPase activity|activation of H(+)/K(+)-ATPase activity|positive regulation of hydrogen:potassium exchanging ATPase activity|up regulation of H+-K+-ATPase activity|up-regulation of H+/K+-exchanging ATPase activity|upregulation of gastric H+/K+ ATPase|positive regulation of gastric H+/K+ ATPase|positive regulation of H(+)/K(+)-exchanging ATPase activity|positive regulation of H+/K+-ATPase activity|upregulation of ATP phosphohydrolase (H+/K+-exchanging)|positive regulation of H+-K+-ATPase activity|activation of hydrogen:potassium-exchanging ATPase activity|activation of hydrogen/potassium-exchanging ATPase activity|positive regulation of ATP phosphohydrolase (H+/K+-exchanging)|up-regulation of hydrogen:potassium-exchanging ATPase activity|up regulation of hydrogen:potassium-exchanging ATPase activity|upregulation of hydrogen:potassium exchanging ATPase activity|upregulation of gastric H(+)/K(+) ATPase activity|upregulation of H,K-ATPase activity|upregulation of H+/K+-ATPase activity|up-regulation of H,K-ATPase activity|positive regulation of H+/K+-exchanging ATPase activity|positive regulation of H(+)/K(+)-ATPase activity|up-regulation of (K+ + H+)-ATPase activity|activation of H+/K+-exchanging ATPase activity						sl	2015-07-08T23:00:15Z						biological_process											owl:Class	
GO:0032336	biolink:NamedThing	negative regulation of activin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.	got7fsn_ti	down-regulation of activin secretion|downregulation of activin secretion|down regulation of activin secretion|inhibition of activin secretion													biological_process											owl:Class	
GO:0051186	biolink:NamedThing	obsolete cofactor metabolic process	OBSOLETE. The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.	got7fsn_ti	cofactor metabolism				1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True				biological_process											owl:Class	
GO:0071234	biolink:NamedThing	cellular response to phenylalanine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.	got7fsn_ti							mah	2009-12-03T02:09:36Z						biological_process											owl:Class	
GO:0097511	biolink:NamedThing	dendritic cell dendrite	A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.	got7fsn_ti							pr	2013-10-16T13:02:25Z						cellular_component											owl:Class	
GO:1901403	biolink:NamedThing	positive regulation of tetrapyrrole metabolic process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.	got7fsn_ti	up regulation of tetrapyrrole metabolism|upregulation of tetrapyrrole metabolic process|positive regulation of tetrapyrrole metabolism|up regulation of tetrapyrrole metabolic process|up-regulation of tetrapyrrole metabolism|up-regulation of tetrapyrrole metabolic process|upregulation of tetrapyrrole metabolism|activation of tetrapyrrole metabolic process|activation of tetrapyrrole metabolism						tt	2012-10-01T14:35:29Z						biological_process											owl:Class	
GO:1990382	biolink:NamedThing	obsolete melanosome assembly	OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.	got7fsn_ti	melanosome biogenesis				This term was obsoleted at the TermGenie Gatekeeper stage.		bf	2014-05-20T16:06:04Z		True				biological_process											owl:Class	
GO:1901920	biolink:NamedThing	peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity	Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity.	got7fsn_ti	peptidyl-tyrosine dephosphorylation involved in protein kinase activation						al	2013-02-15T18:54:53Z						biological_process											owl:Class	
GO:1900229	biolink:NamedThing	negative regulation of single-species biofilm formation in or on host organism	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism.	got7fsn_ti	downregulation of single-species biofilm formation in or on host organism|down regulation of single-species biofilm formation in or on host organism|inhibition of single-species biofilm formation in or on host organism|down-regulation of single-species biofilm formation in or on host organism						di	2012-03-23T04:37:05Z						biological_process											owl:Class	
GO:0001809	biolink:NamedThing	positive regulation of type IV hypersensitivity	Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.	got7fsn_ti	up regulation of type IV hypersensitivity|up-regulation of type IV hypersensitivity|upregulation of type IV hypersensitivity|stimulation of type IV hypersensitivity|activation of type IV hypersensitivity													biological_process											owl:Class	
GO:1905379	biolink:NamedThing	beta-N-acetylhexosaminidase complex	A protein complex which is capable of beta-N-acetylhexosaminidase activity.	got7fsn_ti	HEX S complex|HEX B complex|HEX A complex				An example of this is HEXB in human (UniProt symbol P07686) in PMID:6458607 (inferred from direct assay).		bhm	2016-08-18T08:26:15Z						cellular_component											owl:Class	
GO:1990370	biolink:NamedThing	obsolete process resulting in tolerance to aldehyde	OBSOLETE. A response that results in a state of tolerance to aldehyde.	got7fsn_ti					This term was obsoleted because it does not represent a clear process.		tt	2014-04-23T22:30:50Z		True				biological_process											owl:Class	
GO:0015533	biolink:NamedThing	shikimate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in).	got7fsn_ti	shikimate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0062162	biolink:NamedThing	positive regulation of pyocyanine biosynthetic process	Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process.	got7fsn_ti	positive regulation of pyocyanin biosynthetic process						dph	2019-11-06T14:40:35Z						biological_process											owl:Class	
GO:0008547	biolink:NamedThing	obsolete protein-synthesizing GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. A GTPase involved in protein synthesis. In the initiation factor complex, it is IF-2b (98 kDa) that binds GTP and subsequently hydrolyzes it in prokaryotes. In eukaryotes, it is eIF-2 (150 kDa) that binds GTP. In the elongation phase, the GTP-hydrolyzing proteins are the EF-Tu polypeptide of the prokaryotic transfer factor (43 kDa), the eukaryotic elongation factor EF-1a (53 kDa), the prokaryotic EF-G (77 kDa), the eukaryotic EF-2 (70-110 kDa) and the signal recognition particle that play a role in endoplasmic reticulum protein synthesis (325 kDa). EF-Tu and EF1a catalyze binding of aminoacyl-tRNA to the ribosomal A-site, while EF-G and EF-2 catalyze the translocation of peptidyl-tRNA from the A-site to the P-site. GTPase activity is also involved in polypeptide release from the ribosome with the aid of the pRFs and eRFs.	got7fsn_ti	protein-synthesizing GTPase activity				This term was made obsolete because it represents a gene product.	GO:0008135|GO:0006412|GO:0003924				True				molecular_function											owl:Class	
GO:0007238	biolink:NamedThing	obsolete activation of Pbs2	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of Pbs2				This term was made obsolete because it contains gene product and species specific information.					True				biological_process											owl:Class	
UBERON:0001044	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000005	biolink:NamedThing	obsolete ribosomal chaperone activity	OBSOLETE. Assists in the correct assembly of ribosomes or ribosomal subunits in vivo, but is not a component of the assembled ribosome when performing its normal biological function.	got7fsn_ti	ribosomal chaperone activity				This term was made obsolete because it refers to a class of gene products and a biological process rather than a molecular function.	GO:0044183|GO:0042254|GO:0051082				True				molecular_function											owl:Class	
GO:2000622	biolink:NamedThing	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.	got7fsn_ti	regulation of mRNA catabolic process, nonsense-mediated|regulation of mRNA breakdown, nonsense-mediated decay|regulation of nonsense-mediated mRNA decay|regulation of nuclear mRNA catabolic process, nonsense-mediated decay|regulation of mRNA catabolism, nonsense-mediated|regulation of mRNA degradation, nonsense-mediated decay						pr	2011-04-18T03:32:42Z						biological_process											owl:Class	
GO:0002691	biolink:NamedThing	regulation of cellular extravasation	Any process that modulates the frequency, rate, or extent of cellular extravasation.	got7fsn_ti														biological_process											owl:Class	
GO:0017027	biolink:NamedThing	obsolete transmembrane receptor protein serine/threonine kinase receptor-associated protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transmembrane receptor protein serine/threonine kinase receptor-associated protein activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005102|GO:0005515				True				molecular_function											owl:Class	
GO:1990539	biolink:NamedThing	fructose import across plasma membrane	The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							vw	2014-11-19T10:57:17Z						biological_process											owl:Class	
GO:0140245	biolink:NamedThing	regulation of translation at postsynapse	Any process that regulates translation occurring at the postsynapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/210			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:38:54Z						biological_process											owl:Class	
GO:0001753	biolink:NamedThing	obsolete adult eye photoreceptor development (sensu Drosophila)	OBSOLETE. Development of a photoreceptor, a receptor that responds to light, in the adult Drosophila eye.	got7fsn_ti	adult eye photoreceptor development (sensu Drosophila)				This term was made obsolete because eye photoreceptors have completed their development by the time the adult phase begins.	GO:0042051				True				biological_process											owl:Class	
GO:1904346	biolink:NamedThing	positive regulation of gastric mucosal blood circulation	Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation.	got7fsn_ti	activation of stomach mucosal blood circulation|up regulation of gastric mucosal blood circulation|upregulation of stomach mucosal blood circulation|up regulation of stomach mucosal blood circulation|activation of gastric mucosal blood circulation|upregulation of gastric mucosal blood circulation|up-regulation of gastric mucosal blood circulation|up-regulation of stomach mucosal blood circulation|positive regulation of stomach mucosal blood circulation						sl	2015-06-11T21:20:50Z						biological_process											owl:Class	
GO:0045638	biolink:NamedThing	negative regulation of myeloid cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.	got7fsn_ti	inhibition of myeloid cell differentiation|down regulation of myeloid cell differentiation|downregulation of myeloid cell differentiation|down-regulation of myeloid cell differentiation													biological_process											owl:Class	
GO:0045599	biolink:NamedThing	negative regulation of fat cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.	got7fsn_ti	downregulation of fat cell differentiation|down-regulation of fat cell differentiation|negative regulation of adipocyte cell differentiation|down regulation of fat cell differentiation|inhibition of fat cell differentiation|negative regulation of adipocyte differentiation													biological_process											owl:Class	
GO:0032814	biolink:NamedThing	regulation of natural killer cell activation	Any process that modulates the frequency, rate or extent of natural killer cell activation.	got7fsn_ti	regulation of NK cell activation													biological_process											owl:Class	
GO:0071524	biolink:NamedThing	pyrrolysine biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.	got7fsn_ti	monomethylamine methyltransferase cofactor lysine adduct biosynthetic process|pyrrolysine formation|pyrrolysine anabolism|pyrrolysine biosynthesis|pyrrolysine synthesis						mah	2010-01-07T02:40:24Z						biological_process											owl:Class	
GO:1902154	biolink:NamedThing	positive regulation of response to DNA damage checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling.	got7fsn_ti	activation of response to DNA damage checkpoint signaling|positive regulation of response to signal involved in DNA damage checkpoint|up regulation of response to DNA damage checkpoint signaling|activation of DNA damage checkpoint effector process|up-regulation of response to DNA damage checkpoint signaling|upregulation of response to DNA damage checkpoint signaling|up-regulation of DNA damage checkpoint effector process|up regulation of DNA damage checkpoint effector process|upregulation of response to signal involved in DNA damage checkpoint|up regulation of response to signal involved in DNA damage checkpoint|upregulation of DNA damage checkpoint effector process|positive regulation of DNA damage checkpoint effector process|up-regulation of response to signal involved in DNA damage checkpoint|activation of response to signal involved in DNA damage checkpoint						jl	2013-05-21T15:44:44Z						biological_process											owl:Class	
GO:1902953	biolink:NamedThing	positive regulation of ER to Golgi vesicle-mediated transport	Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.	got7fsn_ti	up-regulation of rough ER to cis-Golgi transport|positive regulation of ER to Golgi transport|up-regulation of rough endoplasmic reticulum to cis-Golgi transport|up regulation of rough ER to cis-Golgi vesicle-mediated transport|up regulation of ER to Golgi transport|activation of rough endoplasmic reticulum to cis-Golgi transport|up-regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|activation of rough ER to cis-Golgi transport|upregulation of ER to Golgi transport|upregulation of rough ER to cis-Golgi vesicle-mediated transport|up regulation of rough ER to cis-Golgi transport|positive regulation of rough endoplasmic reticulum to cis-Golgi transport|activation of endoplasmic reticulum to Golgi transport|positive regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|positive regulation of rough ER to cis-Golgi vesicle-mediated transport|up regulation of endoplasmic reticulum to Golgi transport|up regulation of rough endoplasmic reticulum to cis-Golgi transport|up regulation of ER to Golgi vesicle-mediated transport|positive regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|up-regulation of ER to Golgi vesicle-mediated transport|up-regulation of rough ER to cis-Golgi vesicle-mediated transport|up-regulation of endoplasmic reticulum to Golgi transport|upregulation of endoplasmic reticulum to Golgi vesicle-mediated transport|positive regulation of rough ER to cis-Golgi transport|up-regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|activation of endoplasmic reticulum to Golgi vesicle-mediated transport|up regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|up-regulation of ER to Golgi transport|upregulation of ER to Golgi vesicle-mediated transport|activation of ER to Golgi vesicle-mediated transport|activation of ER to Golgi transport|activation of rough ER to cis-Golgi vesicle-mediated transport|activation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|upregulation of rough ER to cis-Golgi transport|positive regulation of endoplasmic reticulum to Golgi transport|upregulation of rough endoplasmic reticulum to cis-Golgi transport|up regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|upregulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|upregulation of endoplasmic reticulum to Golgi transport						sjp	2014-05-02T08:59:18Z						biological_process											owl:Class	
GO:1905380	biolink:NamedThing	regulation of snRNA transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.	got7fsn_ti	regulation of snRNA transcription from RNA polymerase II promoter|regulation of snRNA transcription from Pol II promoter						bhm	2016-08-18T13:39:20Z						biological_process											owl:Class	
GO:0006280	biolink:NamedThing	obsolete mutagenesis	OBSOLETE. The process by which genetic material undergoes a detectable and heritable structural change. There are three categories of mutation: genome mutations, involving addition or subtraction of one or more whole chromosomes; chromosome mutations, which alter the structure of chromosomes; and gene mutations, where the structure of a gene is altered at the molecular level.	got7fsn_ti	mutagenesis				This term was made obsolete because mutagenesis is not a valid biological process in which gene products would normally participate. Rather, mutations arise from DNA replication errors or damage by an extrinsic agent.	GO:0051276|GO:0006281				True				biological_process											owl:Class	
GO:0045929	biolink:NamedThing	positive regulation of juvenile hormone metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.	got7fsn_ti	up regulation of juvenile hormone metabolic process|upregulation of juvenile hormone metabolic process|activation of juvenile hormone metabolic process|up-regulation of juvenile hormone metabolic process|positive regulation of juvenile hormone metabolism|stimulation of juvenile hormone metabolic process													biological_process											owl:Class	
GO:1903348	biolink:NamedThing	positive regulation of bicellular tight junction assembly	Any process that activates or increases the frequency, rate or extent of tight junction assembly.	got7fsn_ti	activation of tight junction formation|activation of tight junction assembly|up regulation of tight junction assembly|up regulation of tight junction formation|up-regulation of tight junction formation|upregulation of tight junction assembly|upregulation of tight junction formation|positive regulation of tight junction formation|up-regulation of tight junction assembly						pr	2014-08-19T11:05:06Z						biological_process											owl:Class	
GO:1903766	biolink:NamedThing	positive regulation of potassium ion export across plasma membrane	Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane.	got7fsn_ti	activation of potassium ion export across plasma membrane|up regulation of potassium ion export|up regulation of potassium ion export across plasma membrane|positive regulation of potassium ion export|up-regulation of potassium ion export across plasma membrane|upregulation of potassium export|activation of potassium export|upregulation of potassium ion export across plasma membrane|up-regulation of potassium export|up regulation of potassium export|positive regulation of potassium export|activation of potassium ion export|up-regulation of potassium ion export|upregulation of potassium ion export						rl	2013-07-17T16:40:10Z			GO:1902304			biological_process											owl:Class	
GO:0016512	biolink:NamedThing	obsolete endothelin-converting enzyme 1 activity	OBSOLETE. Catalysis of the formation of endothelin 1 by cleavage of the Trp21-Val22 bond in the precursor.	got7fsn_ti	ECE-1 activity|endothelin-converting enzyme 1 activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0002693	biolink:NamedThing	positive regulation of cellular extravasation	Any process that activates or increases the frequency, rate, or extent of cellular extravasation.	got7fsn_ti	upregulation of cellular extravasation|activation of cellular extravasation|up regulation of cellular extravasation|up-regulation of cellular extravasation|stimulation of cellular extravasation													biological_process											owl:Class	
GO:0052157	biolink:NamedThing	obsolete modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response	OBSOLETE. Any process that involves recognition of a microbe-associated molecular pattern, and by which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of microbe-associated molecular pattern-induced innate immune response in other organism involved in symbiotic interaction|modulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|modulation by symbiont of microbe-associated molecular pattern-induced host innate immunity	https://github.com/geneontology/go-ontology/issues/18808			The reason for obsoletion is that this term has been misused.					True	GO:0052296			biological_process											owl:Class	
GO:0042421	biolink:NamedThing	norepinephrine biosynthetic process	The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.	got7fsn_ti	levarterenol biosynthesis|levarterenol biosynthetic process|norepinephrine synthesis|norepinephrine formation|norepinephrine biosynthesis|norepinephrine anabolism|noradrenaline biosynthesis|noradrenaline biosynthetic process													biological_process											owl:Class	
GO:0042885	biolink:NamedThing	microcin B17 transport	The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0033489	biolink:NamedThing	cholesterol biosynthetic process via desmosterol	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.	got7fsn_ti	cholesterol synthesis via desmosterol|cholesterol formation via desmosterol|cholesterol biosynthesis via desmosterol|cholesterol anabolism via desmosterol											MetaCyc:PWY66-4		biological_process											owl:Class	
GO:2000938	biolink:NamedThing	positive regulation of cellotriose catabolic process	Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process.	got7fsn_ti	positive regulation of cellotriose catabolism						tt	2011-08-01T12:45:35Z						biological_process											owl:Class	
GO:1900779	biolink:NamedThing	fumiquinazoline C metabolic process	The chemical reactions and pathways involving fumiquinazoline C.	got7fsn_ti	fumiquinazoline C metabolism						di	2012-06-04T09:30:30Z						biological_process											owl:Class	
GO:0046077	biolink:NamedThing	dUDP metabolic process	The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate.	got7fsn_ti	dUDP metabolism													biological_process											owl:Class	
GO:1901803	biolink:NamedThing	1,5-anhydro-D-fructose biosynthetic process	The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose.	got7fsn_ti	1,5-anhydro-D-fructose formation|1,5-anhydro-D-fructose biosynthesis|1,5-anhydro-D-fructose anabolism|1,5-anhydro-D-fructose synthesis						yaf	2013-01-22T09:56:34Z						biological_process											owl:Class	
GO:2001251	biolink:NamedThing	negative regulation of chromosome organization	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.	got7fsn_ti	negative regulation of maintenance of genome integrity|negative regulation of chromosome organisation|negative regulation of chromosome organization and biogenesis|negative regulation of nuclear genome maintenance						yaf	2011-12-02T02:01:20Z						biological_process											owl:Class	
GO:1902424	biolink:NamedThing	negative regulation of attachment of mitotic spindle microtubules to kinetochore	Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.	got7fsn_ti	inhibition of attachment of spindle microtubules to kinetochore during mitosis|inhibition of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|inhibition of attachment of spindle microtubules to kinetochore involved in mitosis|down-regulation of attachment of spindle microtubules to kinetochore during mitosis|down regulation of attachment of spindle microtubules to mitotic chromosome|negative regulation of attachment of spindle microtubules to mitotic chromosome|down regulation of attachment of spindle microtubules to kinetochore during mitosis|negative regulation of mitotic attachment of spindle microtubules to kinetochore|negative regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|negative regulation of mitotic bipolar attachment|downregulation of attachment of spindle microtubules to mitotic chromosome|down-regulation of attachment of spindle microtubules to kinetochore involved in mitosis|downregulation of mitotic bipolar attachment|down-regulation of mitotic bipolar attachment|inhibition of mitotic bipolar attachment|down-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|downregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|down regulation of mitotic bipolar attachment|downregulation of attachment of spindle microtubules to kinetochore involved in mitosis|down regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|down-regulation of attachment of spindle microtubules to mitotic chromosome|negative regulation of attachment of spindle microtubules to kinetochore involved in mitosis|downregulation of attachment of spindle microtubules to kinetochore during mitosis|inhibition of attachment of spindle microtubules to mitotic chromosome|down regulation of attachment of spindle microtubules to kinetochore involved in mitosis|negative regulation of attachment of spindle microtubules to kinetochore during mitosis						vw	2013-09-19T10:33:46Z						biological_process											owl:Class	
GO:1901117	biolink:NamedThing	cephamycin C catabolic process	The chemical reactions and pathways resulting in the breakdown of cephamycin C.	got7fsn_ti	cephamycin C breakdown|cephamycin C catabolism|cephamycin C degradation						yaf	2012-07-11T03:07:13Z						biological_process											owl:Class	
GO:2000982	biolink:NamedThing	positive regulation of inner ear receptor cell differentiation	Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.	got7fsn_ti	positive regulation of inner ear hair cell differentiation						yaf	2011-08-03T02:38:51Z						biological_process											owl:Class	
GO:2001288	biolink:NamedThing	positive regulation of caveolin-mediated endocytosis	Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis.	got7fsn_ti	positive regulation of caveolae-dependent endocytosis|positive regulation of caveolae-mediated endocytosis|positive regulation of caveolin-dependent endocytosis						yaf	2011-12-15T04:13:32Z						biological_process											owl:Class	
GO:0032206	biolink:NamedThing	positive regulation of telomere maintenance	Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.	got7fsn_ti	stimulation of telomere maintenance|up regulation of telomere maintenance|upregulation of telomere maintenance|up-regulation of telomere maintenance|activation of telomere maintenance													biological_process											owl:Class	
GO:0097049	biolink:NamedThing	motor neuron apoptotic process	Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.	got7fsn_ti	motoneuron apoptosis|motor neuron apoptosis						pr	2011-05-04T02:21:43Z						biological_process											owl:Class	
GO:0051149	biolink:NamedThing	positive regulation of muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.	got7fsn_ti	activation of muscle cell differentiation|up regulation of muscle cell differentiation|up-regulation of muscle cell differentiation|upregulation of muscle cell differentiation|stimulation of muscle cell differentiation													biological_process											owl:Class	
GO:0110046	biolink:NamedThing	signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle	A signal transduction process that contributes to cell cycle switching, mitotic to meiotic cell cycle.	got7fsn_ti							kmv	2017-08-09T12:28:08Z						biological_process											owl:Class	
GO:0000207	biolink:NamedThing	obsolete nuclear translocation of MAPK during sporulation (sensu Saccharomyces)	OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	got7fsn_ti	nuclear translocation of MAPK during sporulation (sensu Saccharomyces)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
CL:0000625	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030280	biolink:NamedThing	structural constituent of skin epidermis	The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure.	got7fsn_ti	structural constituent of epidermis													molecular_function											owl:Class	
GO:0017149	biolink:NamedThing	obsolete protein biosynthetic process inhibitor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	protein biosynthetic process inhibitor activity|protein synthesis inhibitor activity|protein formation inhibitor activity|protein anabolism inhibitor activity			GO:0017148	This term was made obsolete because it represents involvement in a biological process.					True				molecular_function											owl:Class	
UBERON:0005068	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905816	biolink:NamedThing	negative regulation of dorsal/ventral axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance.	got7fsn_ti	negative regulation of dorsal-ventral axon guidance|down regulation of dorsal-ventral axon guidance|down-regulation of dorsal-ventral axon guidance|inhibition of dorsal-ventral axon guidance|down regulation of dorsal/ventral axon pathfinding|down regulation of dorsal/ventral axon guidance|inhibition of dorsal/ventral axon guidance|negative regulation of dorsoventral axon guidance|down regulation of dorsoventral axon guidance|downregulation of dorsal-ventral axon guidance|down-regulation of dorsoventral axon guidance|downregulation of dorsal/ventral axon pathfinding|downregulation of dorsal/ventral axon guidance|inhibition of dorsal/ventral axon pathfinding|downregulation of dorsoventral axon guidance|negative regulation of dorsal/ventral axon pathfinding|down-regulation of dorsal/ventral axon pathfinding|down-regulation of dorsal/ventral axon guidance|inhibition of dorsoventral axon guidance						hbye	2017-01-12T13:38:53Z						biological_process											owl:Class	
GO:0061469	biolink:NamedThing	regulation of type B pancreatic cell proliferation	Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.	got7fsn_ti							dph	2012-11-01T13:16:23Z						biological_process											owl:Class	
GO:1904768	biolink:NamedThing	all-trans-retinol binding	Binding to all-trans-retinol.	got7fsn_ti							kmv	2015-10-27T21:14:47Z						molecular_function											owl:Class	
GO:1900214	biolink:NamedThing	regulation of apoptotic process involved in metanephric collecting duct development	Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.	got7fsn_ti	regulation of apoptotic programmed cell death of metanephric collecting duct development|regulation of programmed cell death by apoptosis of metanephric collecting duct development|regulation of apoptotic program of metanephric collecting duct development|regulation of apoptotic process of metanephric collecting duct development|regulation of apoptosis of metanephric collecting duct development|regulation of type I programmed cell death of metanephric collecting duct development|regulation of apoptotic cell death of metanephric collecting duct development|regulation of signaling (initiator) caspase activity of metanephric collecting duct development						yaf	2012-03-22T10:53:21Z						biological_process											owl:Class	
GO:1903386	biolink:NamedThing	negative regulation of homophilic cell adhesion	Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion.	got7fsn_ti	inhibition of homophilic cell adhesion|down regulation of homophilic cell adhesion|down-regulation of homophilic cell adhesion|downregulation of homophilic cell adhesion						als	2014-08-27T09:57:38Z						biological_process											owl:Class	
GO:2000538	biolink:NamedThing	positive regulation of B cell chemotaxis	Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.	got7fsn_ti							ebc	2011-03-29T09:49:33Z						biological_process											owl:Class	
GO:0034094	biolink:NamedThing	regulation of maintenance of meiotic sister chromatid cohesion	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:2000128	biolink:NamedThing	regulation of octopamine signaling pathway	Any process that modulates the frequency, rate or extent of octopamine signaling pathway.	got7fsn_ti	regulation of octopamine signalling pathway						mah	2010-09-29T09:29:41Z						biological_process											owl:Class	
GO:0140609	biolink:NamedThing	phycocyanobilin biosynthetic process	The chemical reactions or pathway resulting in the formation of phycocyanobilin, which involves the oxidative cleavage of heme by a heme oxygenase (HO) to form biliverdin IX alpha. Biliverdin IX alpha is subsequently converted to phycocyanobilin by a ferredoxin-dependent oxidoreductase (PCYA).	got7fsn_ti	phycocyanobilin biosynthesis	https://github.com/geneontology/go-ontology/issues/20941					pg	2021-02-24T10:02:19Z						biological_process											owl:Class	
GO:0046039	biolink:NamedThing	GTP metabolic process	The chemical reactions and pathways involving GTP, guanosine triphosphate.	got7fsn_ti	GTP metabolism													biological_process											owl:Class	
GO:1902285	biolink:NamedThing	semaphorin-plexin signaling pathway involved in neuron projection guidance	Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.	got7fsn_ti	semaphorin-plexin signalling pathway involved in neuron protrusion guidance|semaphorin-plexin signaling pathway involved in neuronal cell projection guidance|semaphorin-plexin signaling pathway involved in neuron protrusion guidance|semaphorin-plexin signalling pathway involved in neuron projection guidance|semaphorin-plexin signalling pathway involved in neuronal cell projection guidance|semaphorin-plexin signalling pathway involved in neuron process guidance|semaphorin-plexin signaling pathway involved in neurite guidance|semaphorin-plexin signaling pathway involved in neuron process guidance|semaphorin-plexin signalling pathway involved in neurite guidance						pr	2013-07-08T16:06:46Z						biological_process											owl:Class	
GO:0015963	biolink:NamedThing	diadenosine triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.	got7fsn_ti	diadenosine triphosphate synthesis|diadenosine triphosphate formation|diadenosine triphosphate anabolism|diadenosine triphosphate biosynthesis													biological_process											owl:Class	
GO:1904176	biolink:NamedThing	carbon phosphorus lyase complex	A protein complex which is capable of carbon phosphorus lyase activity.	got7fsn_ti					An example of this is PhnJ in E. coli (P16688) in PMID:22089136 (inferred from direct assay).		bhm	2015-04-29T08:17:13Z						cellular_component											owl:Class	
GO:1903694	biolink:NamedThing	obsolete positive regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation.	got7fsn_ti	up regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|positive regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|upregulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|upregulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|up-regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|activation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up-regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|activation of mitotic G1 cell cycle arrest in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/20989			This term was obsoleted because it does not represent a specific process.		al	2014-12-02T18:16:16Z		True				biological_process											owl:Class	
GO:0002891	biolink:NamedThing	positive regulation of immunoglobulin mediated immune response	Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.	got7fsn_ti	upregulation of immunoglobulin mediated immune response|up regulation of immunoglobulin mediated immune response|stimulation of immunoglobulin mediated immune response|activation of immunoglobulin mediated immune response|up-regulation of immunoglobulin mediated immune response													biological_process											owl:Class	
GO:1905464	biolink:NamedThing	positive regulation of DNA duplex unwinding	Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding.	got7fsn_ti	up-regulation of duplex DNA melting|positive regulation of duplex DNA melting|upregulation of duplex DNA melting|up-regulation of DNA unwinding|upregulation of DNA unwinding|activation of DNA duplex unwinding|upregulation of DNA duplex unwinding|up regulation of DNA unwinding|activation of duplex DNA melting|up regulation of DNA duplex unwinding|up regulation of duplex DNA melting|positive regulation of DNA unwinding|activation of DNA unwinding|up-regulation of DNA duplex unwinding						ans	2016-09-19T11:58:55Z						biological_process											owl:Class	
GO:0006905	biolink:NamedThing	obsolete vesicle transport	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	vesicle transport				This term was made obsolete because the meaning of the term is ambiguous.	GO:0016192				True				biological_process											owl:Class	
GO:0030151	biolink:NamedThing	molybdenum ion binding	Binding to a molybdenum ion (Mo).	got7fsn_ti	molybdenum binding|Mo ion binding													molecular_function											owl:Class	
GO:1901988	biolink:NamedThing	negative regulation of cell cycle phase transition	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition.	got7fsn_ti	down-regulation of cell cycle phase transition|negative regulation of cell cycle transition|down regulation of cell cycle transition|downregulation of cell cycle phase transition|down-regulation of cell cycle transition|downregulation of cell cycle transition|down regulation of cell cycle phase transition|inhibition of cell cycle phase transition|inhibition of cell cycle transition						jl	2013-03-19T16:11:32Z						biological_process											owl:Class	
PR:000001439	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018867	biolink:NamedThing	alpha-pinene metabolic process	The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.	got7fsn_ti	alpha-pinene metabolism											UM-BBD_pathwayID:apn		biological_process											owl:Class	
UBERON:0005153	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990642	biolink:NamedThing	obsolete response to castration	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a castration stimulus, deprivation of gonads.	got7fsn_ti	response to castration				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-02-11T18:53:04Z		True				biological_process											owl:Class	
GO:0046642	biolink:NamedThing	negative regulation of alpha-beta T cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation.	got7fsn_ti	downregulation of alpha-beta T cell proliferation|negative regulation of alpha-beta T-lymphocyte proliferation|negative regulation of alpha-beta T-cell proliferation|negative regulation of alpha-beta T lymphocyte proliferation|down regulation of alpha-beta T cell proliferation|inhibition of alpha-beta T cell proliferation|down-regulation of alpha-beta T cell proliferation													biological_process											owl:Class	
GO:0045919	biolink:NamedThing	positive regulation of cytolysis	Any process that activates or increases the frequency, rate or extent of cytolysis.	got7fsn_ti	up-regulation of cytolysis|stimulation of cytolysis|upregulation of cytolysis|up regulation of cytolysis|activation of cytolysis													biological_process											owl:Class	
GO:0001033	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061317	biolink:NamedThing	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment						dph	2010-09-24T09:29:21Z						biological_process											owl:Class	
GO:0032523	biolink:NamedThing	silicon efflux transmembrane transporter activity	Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane.	got7fsn_ti	silicon efflux transporter activity													molecular_function											owl:Class	
GO:1904508	biolink:NamedThing	regulation of protein localization to basolateral plasma membrane	Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane.	got7fsn_ti	regulation of protein localization in basolateral plasma membrane|regulation of protein localisation to basolateral plasma membrane|regulation of protein localisation in basolateral plasma membrane						kmv	2015-07-24T17:56:26Z						biological_process											owl:Class	
GO:1900625	biolink:NamedThing	positive regulation of monocyte aggregation	Any process that activates or increases the frequency, rate or extent of monocyte aggregation.	got7fsn_ti	up regulation of mononuclear phagocyte aggregation|upregulation of mononuclear phagocyte aggregation|up-regulation of mononuclear phagocyte aggregation|activation of mononuclear phagocyte aggregation|activation of monocyte aggregation|upregulation of monocyte aggregation|positive regulation of mononuclear phagocyte aggregation|up regulation of monocyte aggregation|up-regulation of monocyte aggregation						vk	2012-05-21T01:07:44Z						biological_process											owl:Class	
GO:1902843	biolink:NamedThing	positive regulation of netrin-activated signaling pathway	Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway.	got7fsn_ti	upregulation of netrin-activated signal transduction pathway|up-regulation of netrin signaling pathway|up regulation of netrin-activated signaling pathway|upregulation of netrin-activated signaling pathway|up regulation of netrin signaling pathway|upregulation of netrin signaling pathway|positive regulation of netrin-activated signal transduction pathway|up-regulation of netrin-activated signaling pathway|activation of netrin-activated signaling pathway|up-regulation of netrin-activated signalling pathway|upregulation of netrin-mediated signaling pathway|up-regulation of netrin-mediated signaling pathway|positive regulation of netrin signaling pathway|activation of netrin signaling pathway|up regulation of netrin-mediated signaling pathway|activation of netrin-activated signalling pathway|upregulation of netrin-activated signalling pathway|activation of netrin-activated signal transduction pathway|up-regulation of netrin-activated signal transduction pathway|positive regulation of netrin-activated signalling pathway|positive regulation of netrin-mediated signaling pathway|up regulation of netrin-activated signal transduction pathway|activation of netrin-mediated signaling pathway|up regulation of netrin-activated signalling pathway						kmv	2014-04-01T15:25:53Z						biological_process											owl:Class	
GO:0006134	biolink:NamedThing	obsolete dihydrobiopterin reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dihydrobiopterin reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0047040|GO:0051066|GO:0022900				True				biological_process											owl:Class	
GO:0045935	biolink:NamedThing	positive regulation of nucleobase-containing compound metabolic process	Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.	got7fsn_ti	activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process													biological_process											owl:Class	
GO:0021834	biolink:NamedThing	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration	The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb.	got7fsn_ti	negative chemotaxis involved in embryonic olfactory bulb interneuron precursor migration													biological_process											owl:Class	
UBERON:0005155	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901958	biolink:NamedThing	negative regulation of cutin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process.	got7fsn_ti	inhibition of cutin anabolism|inhibition of cutin biosynthesis|negative regulation of cutin biosynthesis|inhibition of cutin biosynthetic process|down-regulation of cutin synthesis|down-regulation of cutin biosynthesis|downregulation of cutin synthesis|downregulation of cutin biosynthesis|inhibition of cutin formation|negative regulation of cutin anabolism|down regulation of cutin anabolism|downregulation of cutin biosynthetic process|down-regulation of cutin formation|negative regulation of cutin formation|downregulation of cutin formation|down-regulation of cutin biosynthetic process|inhibition of cutin synthesis|down regulation of cutin biosynthetic process|down regulation of cutin formation|down regulation of cutin biosynthesis|downregulation of cutin anabolism|negative regulation of cutin synthesis|down regulation of cutin synthesis|down-regulation of cutin anabolism						tb	2013-02-19T19:06:10Z						biological_process											owl:Class	
GO:1900216	biolink:NamedThing	positive regulation of apoptotic process involved in metanephric collecting duct development	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.	got7fsn_ti	up regulation of apoptotic cell death of metanephric collecting duct development|positive regulation of apoptotic cell death of metanephric collecting duct development|up regulation of type I programmed cell death of metanephric collecting duct development|up regulation of signaling (initiator) caspase activity of metanephric collecting duct development|activation of apoptotic process of metanephric collecting duct development|upregulation of apoptosis of metanephric collecting duct development|upregulation of signaling (initiator) caspase activity of metanephric collecting duct development|up-regulation of apoptotic process involved in metanephric collecting duct development|positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development|up-regulation of apoptosis of metanephric collecting duct development|positive regulation of apoptosis of metanephric collecting duct development|up regulation of apoptosis of metanephric collecting duct development|up-regulation of apoptotic programmed cell death of metanephric collecting duct development|up-regulation of apoptotic program of metanephric collecting duct development|activation of apoptotic programmed cell death of metanephric collecting duct development|activation of apoptotic process involved in metanephric collecting duct development|positive regulation of type I programmed cell death of metanephric collecting duct development|up-regulation of programmed cell death by apoptosis of metanephric collecting duct development|up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development|up regulation of apoptotic process of metanephric collecting duct development|activation of signaling (initiator) caspase activity of metanephric collecting duct development|up regulation of programmed cell death by apoptosis of metanephric collecting duct development|activation of type I programmed cell death of metanephric collecting duct development|positive regulation of apoptotic process of metanephric collecting duct development|activation of apoptotic program of metanephric collecting duct development|up-regulation of apoptotic process of metanephric collecting duct development|positive regulation of apoptotic program of metanephric collecting duct development|upregulation of apoptotic process of metanephric collecting duct development|activation of programmed cell death by apoptosis of metanephric collecting duct development|up regulation of apoptotic programmed cell death of metanephric collecting duct development|up regulation of apoptotic program of metanephric collecting duct development|upregulation of type I programmed cell death of metanephric collecting duct development|upregulation of apoptotic cell death of metanephric collecting duct development|activation of apoptosis of metanephric collecting duct development|up-regulation of type I programmed cell death of metanephric collecting duct development|positive regulation of apoptotic programmed cell death of metanephric collecting duct development|upregulation of apoptotic program of metanephric collecting duct development|positive regulation of programmed cell death by apoptosis of metanephric collecting duct development|upregulation of apoptotic programmed cell death of metanephric collecting duct development|activation of apoptotic cell death of metanephric collecting duct development|upregulation of apoptotic process involved in metanephric collecting duct development|up regulation of apoptotic process involved in metanephric collecting duct development|upregulation of programmed cell death by apoptosis of metanephric collecting duct development|up-regulation of apoptotic cell death of metanephric collecting duct development						yaf	2012-03-22T10:53:39Z						biological_process											owl:Class	
GO:0010417	biolink:NamedThing	glucuronoxylan biosynthetic process	The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues.	got7fsn_ti	glucuronoxylan anabolism|glucuronoxylan biosynthesis|glucuronoxylan synthesis|glucuronoxylan formation													biological_process											owl:Class	
GO:0071643	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 4 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.	got7fsn_ti	regulation of MIP-1b production|regulation of macrophage inflammatory protein production|regulation of CCL4 production						mah	2010-02-12T10:39:51Z						biological_process											owl:Class	
GO:0062042	biolink:NamedThing	regulation of cardiac epithelial to mesenchymal transition	Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti							dph	2018-05-10T18:09:31Z						biological_process											owl:Class	
GO:1904481	biolink:NamedThing	response to tetrahydrofolate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.	got7fsn_ti							hal	2015-07-14T14:49:17Z						biological_process											owl:Class	
GO:1905454	biolink:NamedThing	negative regulation of myeloid progenitor cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation.	got7fsn_ti	down regulation of myeloid progenitor cell differentiation|inhibition of myeloid progenitor cell differentiation|downregulation of myeloid progenitor cell differentiation|down-regulation of myeloid progenitor cell differentiation						rz	2016-09-16T12:32:26Z						biological_process											owl:Class	
GO:0061813	biolink:NamedThing	obsolete ARID domain binding	OBSOLETE. Binding to a ARID domain. The AT-rich interaction domain (ARID) is an ~100-amino acid DNA-binding module found in a large number of eukaryotic transcription factors.	got7fsn_ti							dph	2016-11-11T13:57:55Z		True				molecular_function											owl:Class	
GO:1900999	biolink:NamedThing	nitrobenzene biosynthetic process	The chemical reactions and pathways resulting in the formation of nitrobenzene.	got7fsn_ti	nitrobenzene biosynthesis|nitrobenzene anabolism|nitrobenzene synthesis|nitrobenzene formation						yaf	2012-06-14T02:54:32Z						biological_process											owl:Class	
GO:1901919	biolink:NamedThing	positive regulation of exoribonuclease activity	Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.	got7fsn_ti	upregulation of exoribonuclease activity|activation of exoribonuclease activity|up regulation of exoribonuclease activity|up-regulation of exoribonuclease activity						rb	2013-02-15T00:58:07Z						biological_process											owl:Class	
GO:0140435	biolink:NamedThing	negative regulation of protein localization to meiotic spindle pole body	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body.	got7fsn_ti							pg	2020-02-24T13:27:15Z						biological_process											owl:Class	
GO:0032379	biolink:NamedThing	positive regulation of intracellular lipid transport	Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.	got7fsn_ti	up-regulation of intracellular lipid transport|stimulation of intracellular lipid transport|activation of intracellular lipid transport|up regulation of intracellular lipid transport|upregulation of intracellular lipid transport													biological_process											owl:Class	
GO:0003781	biolink:NamedThing	obsolete actin bundling activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	actin bundling activity			GO:0051017	This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:1903019	biolink:NamedThing	negative regulation of glycoprotein metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.	got7fsn_ti	down-regulation of glycoprotein metabolism|down regulation of glycoprotein metabolism|downregulation of glycoprotein metabolism|down regulation of glycoprotein metabolic process|inhibition of glycoprotein metabolic process|downregulation of glycoprotein metabolic process|negative regulation of glycoprotein metabolism|down-regulation of glycoprotein metabolic process|inhibition of glycoprotein metabolism				human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein		rl	2014-05-14T18:44:25Z						biological_process											owl:Class	
GO:1990894	biolink:NamedThing	obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion.	got7fsn_ti					This term was obsoleted during the TG review process.  It should have been created using a template.		al	2015-11-04T20:25:21Z		True				biological_process											owl:Class	
GO:0035273	biolink:NamedThing	phthalate binding	Binding to a phthalate, any ester or salt of phthalic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0080038	biolink:NamedThing	positive regulation of cytokinin-activated signaling pathway	Any process that activates or increases the frequency, rate or extent of cytokinin signaling.	got7fsn_ti	positive regulation of cytokinin mediated signaling pathway|positive regulation of cytokinin mediated signalling													biological_process											owl:Class	
GO:1902058	biolink:NamedThing	regulation of sporocarp development involved in sexual reproduction	Any process that modulates the frequency, rate or extent of sporocarp development involved in sexual reproduction.	got7fsn_ti	regulation of perfect stage fruiting body development|regulation of fruiting body development involved in sexual reproduction|regulation of fruiting body formation involved in sexual reproduction|regulation of ascus development						di	2013-04-16T04:08:38Z						biological_process											owl:Class	
GO:1904914	biolink:NamedThing	negative regulation of establishment of protein-containing complex localization to telomere	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.	got7fsn_ti	negative regulation of establishment of macromolecular complex localisation to telomere|downregulation of establishment of macromolecular complex localization to telomere|down regulation of establishment of macromolecular complex localisation to telomere|downregulation of establishment of macromolecular complex localisation to telomere|inhibition of establishment of macromolecular complex localization to telomere|down-regulation of establishment of macromolecular complex localisation to telomere|negative regulation of establishment of macromolecular complex localization to telomere|down-regulation of establishment of macromolecular complex localization to telomere|down regulation of establishment of macromolecular complex localization to telomere|inhibition of establishment of macromolecular complex localisation to telomere						rph	2016-01-19T10:38:29Z						biological_process											owl:Class	
GO:0070605	biolink:NamedThing	regulation of (1->3)-alpha-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.	got7fsn_ti	regulation of alpha-1,3 glucan metabolism|regulation of alpha-1,3 glucan metabolic process|regulation of 1,3-alpha-glucan metabolic process|regulation of 1,3-alpha-glucan metabolism						mah	2009-04-29T01:20:12Z						biological_process											owl:Class	
GO:0061941	biolink:NamedThing	positive regulation of c-di-GMP signaling	Any process that increases the rate, frequency or extent of c-di-GMP signaling.	got7fsn_ti							dph	2017-09-14T19:11:15Z						biological_process											owl:Class	
GO:0043266	biolink:NamedThing	regulation of potassium ion transport	Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of potassium conductance|regulation of potassium transport|regulation of potassium ion conductance|regulation of K+ transport|regulation of K+ conductance													biological_process											owl:Class	
GO:0072400	biolink:NamedThing	obsolete detection of stimulus involved in mitotic DNA integrity checkpoint	OBSOLETE. The series of events in which information about DNA integrity is received and converted into a molecular signal, contributing to a mitotic DNA integrity checkpoint.	got7fsn_ti	sensing involved in DNA integrity checkpoint|mitotic G2/M transition decatenation checkpoint sensor process|mitotic G2/M transition decatenation checkpoint sensor mechanism|detection of stimulus involved in mitotic G2/M transition decatenation checkpoint|DNA integrity checkpoint sensor process|DNA integrity checkpoint sensor mechanism|sensing involved in mitotic G2/M transition decatenation checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:29:11Z		True	GO:0072457			biological_process											owl:Class	
GO:1903743	biolink:NamedThing	negative regulation of anterograde synaptic vesicle transport	Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport.	got7fsn_ti	downregulation of anterograde synaptic vesicle transport|down-regulation of anterograde synaptic vesicle transport|inhibition of anterograde synaptic vesicle transport|down regulation of anterograde synaptic vesicle transport						kmv	2014-12-12T16:28:37Z						biological_process											owl:Class	
GO:0052235	biolink:NamedThing	obsolete negative aerotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative aerotaxis in other organism during symbiotic interaction|negative aerotaxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0031276	biolink:NamedThing	obsolete negative regulation of lateral pseudopodium assembly	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.	got7fsn_ti	inhibition of lateral pseudopodium formation|down regulation of lateral pseudopodium formation|down-regulation of lateral pseudopodium formation|negative regulation of lateral pseudopodium formation|downregulation of lateral pseudopodium formation	https://github.com/geneontology/go-ontology/issues/21738		GO:0120320	The regulation of lateral pseudopodium assembly terms were not used consistently. The negative regulation term has been replaced by GO:0120320 lateral pseudopodium retraction.					True				biological_process											owl:Class	
GO:0015984	biolink:NamedThing	obsolete uniport	OBSOLETE. The process of noncoupled solute translocation or facilitated diffusion.	got7fsn_ti	uniport			GO:0015292	This term was made obsolete because it represents a molecular function rather than a biological process.					True				biological_process											owl:Class	
GO:0043105	biolink:NamedThing	negative regulation of GTP cyclohydrolase I activity	Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I.	got7fsn_ti	down-regulation of GTP cyclohydrolase I activity|downregulation of GTP cyclohydrolase I activity|down regulation of GTP cyclohydrolase I activity|inhibition of GTP cyclohydrolase I activity													biological_process											owl:Class	
GO:0002896	biolink:NamedThing	negative regulation of central B cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.	got7fsn_ti	down regulation of central B cell tolerance induction|inhibition of central B cell tolerance induction|downregulation of central B cell tolerance induction|down-regulation of central B cell tolerance induction													biological_process											owl:Class	
GO:0051295	biolink:NamedThing	establishment of meiotic spindle localization	The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.	got7fsn_ti	establishment of meiotic spindle localisation|spindle positioning involved in meiotic cell cycle|meiotic spindle positioning|spindle positioning during meiosis													biological_process											owl:Class	
GO:1904617	biolink:NamedThing	negative regulation of actin binding	Any process that stops, prevents or reduces the frequency, rate or extent of actin binding.	got7fsn_ti	down regulation of actin binding|downregulation of membrane associated actin binding|negative regulation of membrane associated actin binding|inhibition of actin binding|down-regulation of membrane associated actin binding|inhibition of membrane associated actin binding|downregulation of actin binding|down regulation of membrane associated actin binding|down-regulation of actin binding						mr	2015-08-27T19:09:02Z						biological_process											owl:Class	
GO:0052108	biolink:NamedThing	obsolete growth or development of symbiont during interaction with host	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of organism in response to host|growth or development of organism during interaction with host|growth or development of symbiont during interaction with host				This term was made obsolete because it contained a conjunction (or).	GO:0051701|GO:0044111				True				biological_process											owl:Class	
GO:2000347	biolink:NamedThing	positive regulation of hepatocyte proliferation	Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.	got7fsn_ti							mah	2011-02-03T10:27:24Z						biological_process											owl:Class	
GO:0075085	biolink:NamedThing	obsolete positive regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|stimulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|upregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|positive regulation by host of symbiont transmembrane receptor-mediated cAMP signaling|promotion by host of symbiont transmembrane receptor protein activity involved in cAMP-mediated signal transduction				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:2001070	biolink:NamedThing	starch binding	Binding to starch.	got7fsn_ti	amylum binding|amidon binding						jl	2011-09-14T12:02:50Z						molecular_function											owl:Class	
GO:0009661	biolink:NamedThing	chromoplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.	got7fsn_ti	chromoplast organization and biogenesis|chromoplast organisation													biological_process											owl:Class	
GO:1900895	biolink:NamedThing	positive regulation of tridecane metabolic process	Any process that activates or increases the frequency, rate or extent of tridecane metabolic process.	got7fsn_ti	upregulation of tridecane metabolism|up regulation of tridecane metabolic process|activation of tridecane metabolic process|up-regulation of tridecane metabolic process|upregulation of tridecane metabolic process|positive regulation of tridecane metabolism|up-regulation of tridecane metabolism|up regulation of tridecane metabolism|activation of tridecane metabolism						tt	2012-06-13T03:15:11Z						biological_process											owl:Class	
GO:0052484	biolink:NamedThing	obsolete negative regulation by organism of symbiont ethylene-mediated defense response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	suppression by organism of symbiont ethylene-mediated defense response|negative regulation by organism of symbiont ethylene-mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1902832	biolink:NamedThing	negative regulation of cell proliferation in dorsal spinal cord	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.	got7fsn_ti	down regulation of cell proliferation in dorsal spinal cord|inhibition of cell proliferation in dorsal spinal cord|downregulation of cell proliferation in dorsal spinal cord|down-regulation of cell proliferation in dorsal spinal cord						mr	2014-03-31T17:42:50Z						biological_process											owl:Class	
GO:0009469	biolink:NamedThing	obsolete class II cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	class II cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0061313	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in heart development	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.	got7fsn_ti	fibroblast growth factor receptor signalling pathway involved in heart development						dph	2010-09-24T08:15:08Z						biological_process											owl:Class	
GO:0007101	biolink:NamedThing	obsolete male meiosis centrosome cycle	OBSOLETE. Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism.	got7fsn_ti	centrosome cycle involved in male meiotic cell cycle				false					True				biological_process											owl:Class	
GO:0060994	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in kidney development	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state.	got7fsn_ti							dph	2010-01-19T08:24:46Z						biological_process											owl:Class	
GO:0009794	biolink:NamedThing	regulation of mitotic cell cycle, embryonic	Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.	got7fsn_ti	embryonic mitotic cell cycle regulator|regulation of progression through embryonic mitotic cell cycle|regulation of embryonic mitotic cell cycle progression|modulation of embryonic mitotic cell cycle progression|embryonic mitotic cell cycle regulation|embryonic mitotic cell cycle modulation|regulation of embryonic mitotic cell cycle													biological_process											owl:Class	
GO:1905797	biolink:NamedThing	negative regulation of intraciliary anterograde transport	Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport.	got7fsn_ti	down-regulation of intraciliary anterograde transport|inhibition of intraflagellar anterograde transport|negative regulation of intraflagellar anterograde transport|downregulation of intraflagellar anterograde transport|inhibition of intraciliary anterograde transport|down-regulation of intraflagellar anterograde transport|downregulation of intraciliary anterograde transport|down regulation of intraciliary anterograde transport|down regulation of intraflagellar anterograde transport						hbye	2017-01-11T12:55:53Z						biological_process											owl:Class	
GO:1902216	biolink:NamedThing	positive regulation of interleukin-4-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway.	got7fsn_ti	up-regulation of IL-4-mediated signaling pathway|activation of interleukin-4-mediated signaling pathway|activation of IL-4-mediated signaling pathway|up regulation of interleukin-4-mediated signalling pathway|up-regulation of interleukin-4-mediated signalling pathway|positive regulation of IL-4-mediated signaling pathway|activation of interleukin-4-mediated signalling pathway|up-regulation of interleukin-4-mediated signaling pathway|up regulation of IL-4-mediated signaling pathway|up regulation of interleukin-4-mediated signaling pathway|positive regulation of interleukin-4-mediated signalling pathway|upregulation of interleukin-4-mediated signalling pathway|upregulation of interleukin-4-mediated signaling pathway|upregulation of IL-4-mediated signaling pathway						lb	2013-06-12T12:53:20Z						biological_process											owl:Class	
GO:2000111	biolink:NamedThing	positive regulation of macrophage apoptotic process	Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.	got7fsn_ti	positive regulation of AICD|positive regulation of activation-induced cell death|positive regulation of macrophage apoptosis						mah	2010-09-15T01:44:21Z						biological_process											owl:Class	
GO:0016816	biolink:NamedThing	obsolete hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds	OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles.	got7fsn_ti	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds				This term was made obsolete because it was an unnecessary grouping term.	GO:0016810				True				molecular_function											owl:Class	
GO:2000644	biolink:NamedThing	regulation of receptor catabolic process	Any process that modulates the frequency, rate or extent of receptor catabolic process.	got7fsn_ti	regulation of receptor breakdown|regulation of receptor catabolism|regulation of receptor degradation						vk	2011-04-21T11:20:18Z						biological_process											owl:Class	
GO:0046235	biolink:NamedThing	obsolete gallate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).	got7fsn_ti	gallate synthesis|gallic acid biosynthetic process|gallate biosynthesis|gallate anabolism|gallate formation|gallic acid biosynthesis				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1901183	biolink:NamedThing	positive regulation of camalexin biosynthetic process	Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process.	got7fsn_ti	activation of camalexin biosynthesis|upregulation of camalexin anabolism|up regulation of camalexin biosynthesis|upregulation of camalexin biosynthetic process|upregulation of camalexin biosynthesis|activation of camalexin anabolism|activation of camalexin synthesis|upregulation of camalexin synthesis|activation of camalexin formation|positive regulation of camalexin formation|activation of camalexin biosynthetic process|up-regulation of camalexin synthesis|positive regulation of camalexin biosynthesis|up regulation of camalexin synthesis|up-regulation of camalexin anabolism|upregulation of camalexin formation|positive regulation of camalexin synthesis|up regulation of camalexin anabolism|positive regulation of camalexin anabolism|up regulation of camalexin formation|up-regulation of camalexin formation|up-regulation of camalexin biosynthesis|up-regulation of camalexin biosynthetic process|up regulation of camalexin biosynthetic process						tb	2012-07-23T02:17:21Z						biological_process											owl:Class	
GO:0019510	biolink:NamedThing	S-adenosylhomocysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.	got7fsn_ti	S-adenosylhomocysteine degradation|S-adenosylhomocysteine breakdown|S-adenosylhomocysteine catabolism											MetaCyc:ADENOSYLHOMOCYSCAT-PWY		biological_process											owl:Class	
GO:1904117	biolink:NamedThing	cellular response to vasopressin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.	got7fsn_ti							sl	2015-04-06T19:39:48Z						biological_process											owl:Class	
GO:0060544	biolink:NamedThing	regulation of necroptotic process	Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.	got7fsn_ti	regulation of necroptosis						dph	2009-04-13T01:43:22Z						biological_process											owl:Class	
GO:0030567	biolink:NamedThing	obsolete thrombin activator activity	OBSOLETE. Increases the rate of proteolysis catalyzed by thrombin.	got7fsn_ti	thrombin activator activity|prothrombin activator activity			GO:0016504	This term was made obsolete because it represents a regulator of an obsolete molecular function.					True				molecular_function											owl:Class	
GO:0110140	biolink:NamedThing	flagellum attachment zone organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.	got7fsn_ti	FAZ organization|flagellum attachment zone organisation						kmv	2019-03-04T19:55:50Z						biological_process											owl:Class	
GO:0019242	biolink:NamedThing	methylglyoxal biosynthetic process	The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.	got7fsn_ti	methylglyoxal biosynthesis|methylglyoxal anabolism|methylglyoxal synthesis|methylglyoxal formation													biological_process											owl:Class	
GO:0008322	biolink:NamedThing	obsolete Pro-X carboxypeptidase activity	OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond to release a C-terminal amino acid.	got7fsn_ti	Pro-X carboxypeptidase activity			GO:0030536	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0005371	biolink:NamedThing	tricarboxylate secondary active transmembrane transporter activity	Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	tricarboxylate carrier activity										GO:0005370			molecular_function											owl:Class	
GO:0036254	biolink:NamedThing	cellular response to amiloride	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus.	got7fsn_ti							bf	2012-06-15T01:06:16Z						biological_process											owl:Class	
GO:0140667	biolink:NamedThing	regulation of oxytocin production	Any process that modulates the frequency, rate, or extent of production of oxytocin.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21535					pg	2021-06-24T11:28:07Z						biological_process											owl:Class	
GO:0140255	biolink:NamedThing	regulation of cellular response to phosphate starvation	Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation.	got7fsn_ti							pg	2018-09-07T17:11:42Z						biological_process											owl:Class	
GO:0006132	biolink:NamedThing	obsolete dihydrolipoylprotein reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dihydrolipoylprotein reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0004148|GO:0022900				True				biological_process											owl:Class	
GO:1903127	biolink:NamedThing	positive regulation of centriole-centriole cohesion	Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion.	got7fsn_ti	activation of centriole-centriole cohesion|upregulation of centriole-centriole cohesion|up regulation of centriole-centriole cohesion|up-regulation of centriole-centriole cohesion						als	2014-06-24T09:31:51Z						biological_process											owl:Class	
GO:0075230	biolink:NamedThing	obsolete spore movement on or near host	OBSOLETE. Any process involved in the directed movement of a motile spore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:2000494	biolink:NamedThing	positive regulation of interleukin-18-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway.	got7fsn_ti	positive regulation of interleukin-18-mediated signalling pathway						pr	2011-03-16T02:00:50Z						biological_process											owl:Class	
GO:0045635	biolink:NamedThing	negative regulation of melanocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.	got7fsn_ti	inhibition of melanocyte differentiation|negative regulation of melanophore differentiation|down regulation of melanocyte differentiation|down-regulation of melanocyte differentiation|downregulation of melanocyte differentiation													biological_process											owl:Class	
GO:1903955	biolink:NamedThing	positive regulation of protein targeting to mitochondrion	Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.	got7fsn_ti	up regulation of mitochondrial translocation|positive regulation of protein-mitochondrial targeting|up-regulation of protein-mitochondrial targeting|up-regulation of protein import into mitochondrion|up regulation of protein-mitochondrial targeting|positive regulation of protein targeting to mitochondria|up regulation of protein targeting to mitochondrion|upregulation of protein import into mitochondrion|upregulation of protein-mitochondrial targeting|up regulation of mitochondrial protein import|up regulation of protein targeting to mitochondria|upregulation of protein targeting to mitochondria|activation of mitochondrial protein import|activation of protein import into mitochondrion|upregulation of protein targeting to mitochondrion|positive regulation of mitochondrial protein import|upregulation of mitochondrial translocation|up-regulation of protein targeting to mitochondrion|up-regulation of mitochondrial translocation|positive regulation of protein import into mitochondrion|activation of protein targeting to mitochondria|activation of protein-mitochondrial targeting|activation of protein targeting to mitochondrion|up regulation of protein import into mitochondrion|up-regulation of mitochondrial protein import|activation of mitochondrial translocation|positive regulation of mitochondrial translocation|up-regulation of protein targeting to mitochondria|upregulation of mitochondrial protein import				An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype.		pad	2015-02-24T16:58:21Z						biological_process											owl:Class	
GO:0015408	biolink:NamedThing	ABC-type ferric iron transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in).	got7fsn_ti	ferric ABC transporter|ferric transporting ATPase activity|Fe3+-transporting ATPase activity|ferric-transporting ATPase activity|ATPase-coupled ferric iron transmembrane transporter activity|ABC-type Fe3+ transporter											EC:7.2.2.7|MetaCyc:3.6.3.30-RXN|RHEA:12332		molecular_function											owl:Class	
GO:0100037	biolink:NamedThing	obsolete positive regulation of cellular alcohol catabolic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates cellular alcohol catabolic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1900018	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex	Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex.	got7fsn_ti							bf	2012-01-11T11:40:41Z						biological_process											owl:Class	
GO:0035395	biolink:NamedThing	negative regulation of chemokine (C-X-C motif) ligand 9 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.	got7fsn_ti	negative regulation of CXCL9 production|negative regulation of MIG production						bf	2010-03-23T10:06:44Z						biological_process											owl:Class	
GO:0007551	biolink:NamedThing	obsolete maintenance of dosage compensation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	maintenance of dosage compensation				This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms.	GO:0007549				True				biological_process											owl:Class	
GO:0006647	biolink:NamedThing	phosphatidyl-N-monomethylethanolamine biosynthetic process	The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group.	got7fsn_ti	phosphatidyl-N-monomethylethanolamine synthesis|phosphatidyl-N-monomethylethanolamine anabolism|PMME biosynthesis|phosphatidyl-N-monomethylethanolamine formation|phosphatidyl-N-monomethylethanolamine biosynthesis|PMME biosynthetic process													biological_process											owl:Class	
GO:1900937	biolink:NamedThing	positive regulation of nonadec-1-ene biosynthetic process	Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process.	got7fsn_ti	positive regulation of nonadec-1-ene biosynthesis|upregulation of nonadec-1-ene formation|activation of nonadec-1-ene anabolism|up regulation of nonadec-1-ene anabolism|up regulation of nonadec-1-ene biosynthetic process|up-regulation of nonadec-1-ene biosynthesis|up-regulation of nonadec-1-ene synthesis|upregulation of nonadec-1-ene synthesis|up regulation of nonadec-1-ene formation|upregulation of nonadec-1-ene biosynthetic process|activation of nonadec-1-ene formation|positive regulation of nonadec-1-ene synthesis|upregulation of nonadec-1-ene anabolism|up regulation of nonadec-1-ene biosynthesis|up regulation of nonadec-1-ene synthesis|upregulation of nonadec-1-ene biosynthesis|up-regulation of nonadec-1-ene anabolism|up-regulation of nonadec-1-ene formation|activation of nonadec-1-ene biosynthesis|positive regulation of nonadec-1-ene anabolism|activation of nonadec-1-ene biosynthetic process|positive regulation of nonadec-1-ene formation|activation of nonadec-1-ene synthesis|up-regulation of nonadec-1-ene biosynthetic process						tt	2012-06-14T03:14:04Z						biological_process											owl:Class	
GO:0090364	biolink:NamedThing	regulation of proteasome assembly	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.	got7fsn_ti							tb	2010-07-12T10:55:21Z						biological_process											owl:Class	
GO:1900936	biolink:NamedThing	negative regulation of nonadec-1-ene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process.	got7fsn_ti	negative regulation of nonadec-1-ene biosynthesis|inhibition of nonadec-1-ene synthesis|downregulation of nonadec-1-ene biosynthesis|down-regulation of nonadec-1-ene anabolism|inhibition of nonadec-1-ene formation|down regulation of nonadec-1-ene anabolism|down regulation of nonadec-1-ene biosynthetic process|inhibition of nonadec-1-ene biosynthesis|down regulation of nonadec-1-ene formation|negative regulation of nonadec-1-ene synthesis|inhibition of nonadec-1-ene anabolism|down-regulation of nonadec-1-ene synthesis|negative regulation of nonadec-1-ene anabolism|down-regulation of nonadec-1-ene biosynthesis|down regulation of nonadec-1-ene biosynthesis|downregulation of nonadec-1-ene anabolism|inhibition of nonadec-1-ene biosynthetic process|downregulation of nonadec-1-ene synthesis|down-regulation of nonadec-1-ene biosynthetic process|down-regulation of nonadec-1-ene formation|downregulation of nonadec-1-ene formation|negative regulation of nonadec-1-ene formation|down regulation of nonadec-1-ene synthesis|downregulation of nonadec-1-ene biosynthetic process						tt	2012-06-14T03:13:56Z						biological_process											owl:Class	
GO:1900013	biolink:NamedThing	obsolete cellular response to potassium ion involved in chemotaxis to cAMP	OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.	got7fsn_ti	cellular response to K+ ion of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to cyclic AMP|cellular response to potassium of chemotaxis to cyclic AMP|cellular response to potassium ion of chemotaxis to cAMP|cellular response to potassium ion involved in chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to potassium of chemotaxis to cAMP|cellular response to K+ ion of chemotaxis to cyclic AMP|cellular response to K+ ion of chemotaxis to 3',5'-cAMP|cellular response to K+ ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to potassium of chemotaxis to 3',5'-cAMP|cellular response to K+ ion of chemotaxis to 3',5' cAMP|cellular response to potassium ion of chemotaxis to 3',5'-cAMP|cellular response to potassium of chemotaxis to 3',5' cAMP|cellular response to potassium of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to potassium ion of chemotaxis to 3',5' cAMP				This term was made obsolete because it was added by mistake.		pr	2012-01-11T07:59:57Z		True				biological_process											owl:Class	
GO:0033122	biolink:NamedThing	negative regulation of purine nucleotide catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.	got7fsn_ti	negative regulation of purine nucleotide degradation|negative regulation of purine nucleotide breakdown|negative regulation of purine nucleotide catabolism													biological_process											owl:Class	
GO:0035558	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling	OBSOLETE. The process in which a signal is passed from the insulin receptor to components of the phosphatidylinositol 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	got7fsn_ti	phosphoinositide 3-kinase cascade involved in insulin receptor signalling|phosphoinositide 3-kinase cascade involved in insulin receptor signaling|PI3K cascade involved in signaling from the insulin receptor|phosphatidylinositol 3-kinase cascade involved in insulin receptor signalling|phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling				This term was made obsolete because the syntax of the term is incorrect.	GO:0038028	bf	2010-05-14T01:34:38Z		True				biological_process											owl:Class	
GO:0072490	biolink:NamedThing	toluene-containing compound metabolic process	The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives.	got7fsn_ti	toluene and derivative metabolic process|toluene-containing compound metabolism						mah	2010-12-14T03:46:52Z						biological_process											owl:Class	
GO:1904922	biolink:NamedThing	obsolete positive regulation of MAPK cascade involved in axon regeneration	OBSOLETE. Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in axon regeneration.	got7fsn_ti	upregulation of MAPKKK cascade during sporulation involved in axon regeneration|positive regulation of MAPK signaling involved in axon regeneration|up regulation of MAP kinase cascade involved in axon regeneration|upregulation of MAPKKK cascade involved in axon regeneration|upregulation of ERK/MAPK cascade involved in axon regeneration|activation of MAPK signal transduction involved in axon regeneration|activation of MAPK signaling involved in axon regeneration|activation of MAPKKK cascade during sporulation involved in axon regeneration|positive regulation of mitogen-activated protein kinase cascade involved in axon regeneration|activation of MAPK signalling involved in axon regeneration|upregulation of MAPK signalling involved in axon regeneration|activation of MAP kinase cascade involved in axon regeneration|up-regulation of MAP kinase cascade involved in axon regeneration|up regulation of MAP kinase kinase kinase cascade involved in axon regeneration|positive regulation of MAPK signalling involved in axon regeneration|positive regulation of MAPKKK cascade during sporulation involved in axon regeneration|up-regulation of MAPKKK cascade during sporulation involved in axon regeneration|up-regulation of ERK/MAPK cascade involved in axon regeneration|positive regulation of MAPKKK cascade involved in axon regeneration|positive regulation of MAP kinase kinase kinase cascade involved in axon regeneration|up regulation of ERK/MAPK cascade involved in axon regeneration|up-regulation of MAPK signalling involved in axon regeneration|activation of MAPKKK cascade involved in axon regeneration|upregulation of MAP kinase cascade involved in axon regeneration|up-regulation of MAPKKK cascade involved in axon regeneration|up regulation of MAPK cascade involved in axon regeneration|upregulation of MAP kinase kinase kinase cascade involved in axon regeneration|up-regulation of MAPK signal transduction involved in axon regeneration|upregulation of MAPK cascade involved in axon regeneration|upregulation of MAPK signal transduction involved in axon regeneration|up-regulation of MAP kinase kinase kinase cascade involved in axon regeneration|positive regulation of MAPK signal transduction involved in axon regeneration|up-regulation of mitogen-activated protein kinase cascade involved in axon regeneration|up-regulation of MAPK signaling involved in axon regeneration|up regulation of MAPK signal transduction involved in axon regeneration|up regulation of MAPK signaling involved in axon regeneration|activation of ERK/MAPK cascade involved in axon regeneration|up-regulation of MAPK cascade involved in axon regeneration|up regulation of MAPK signalling involved in axon regeneration|up regulation of MAPKKK cascade during sporulation involved in axon regeneration|positive regulation of MAP kinase cascade involved in axon regeneration|upregulation of mitogen-activated protein kinase cascade involved in axon regeneration|up regulation of mitogen-activated protein kinase cascade involved in axon regeneration|activation of mitogen-activated protein kinase cascade involved in axon regeneration|activation of MAP kinase kinase kinase cascade involved in axon regeneration|upregulation of MAPK signaling involved in axon regeneration|activation of MAPK cascade involved in axon regeneration|positive regulation of ERK/MAPK cascade involved in axon regeneration|up regulation of MAPKKK cascade involved in axon regeneration	https://github.com/geneontology/go-ontology/issues/14323			This term was obsoleted because it represents a GO-CAM model.		kmv	2016-01-25T17:03:49Z		True				biological_process											owl:Class	
GO:0032803	biolink:NamedThing	regulation of low-density lipoprotein particle receptor catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.	got7fsn_ti	regulation of low-density lipoprotein receptor catabolism|regulation of low-density lipoprotein receptor breakdown|regulation of low-density lipoprotein receptor degradation|regulation of LDLr catabolism|regulation of low-density lipoprotein receptor catabolic process|regulation of LDLr catabolic process													biological_process											owl:Class	
GO:1990436	biolink:NamedThing	obsolete MAPK cascade involved in oxidative stress signaling pathway	OBSOLETE. A series of molecular signals in which a MAP kinase cascade activated by oxidative stress relays one or more of the signals, MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. Just FYI in pombe the osmotic stress and oxidative stress MAPK cascade involve many of the same proteins, but the pathways are slightly different, therefore Im req this term.	got7fsn_ti	MAPK cascade involved in oxidative stress signaling pathway				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-07-31T10:10:38Z		True				biological_process											owl:Class	
GO:0018853	biolink:NamedThing	obsolete perillyl-CoA synthetase activity	OBSOLETE. Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + perillyl-CoA.	got7fsn_ti	perillyl-CoA synthetase activity				This term was made obsolete because it represents two reactions.	GO:0052685|GO:0052686				True		EC:6.2.1.-|UM-BBD_reactionID:r0731		molecular_function											owl:Class	
GO:1904982	biolink:NamedThing	sucrose transmembrane transport	The process in which sucrose is transported across a membrane.	got7fsn_ti							vw	2016-02-28T21:16:51Z						biological_process											owl:Class	
GO:0018960	biolink:NamedThing	4-nitrophenol metabolic process	The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.	got7fsn_ti	4-nitrophenol metabolism|p-nitrophenol metabolism|p-nitrophenol metabolic process											UM-BBD_pathwayID:nphe		biological_process											owl:Class	
GO:1902042	biolink:NamedThing	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.	got7fsn_ti	down regulation of death receptor-mediated apoptosis|downregulation of extrinsic apoptotic signaling pathway via death domain receptors|down-regulation of death receptor-mediated apoptosis|inhibition of extrinsic apoptotic signaling pathway via death domain receptors|down regulation of extrinsic apoptotic signaling pathway via death domain receptors|down-regulation of extrinsic apoptotic signaling pathway via death domain receptors|inhibition of death receptor-mediated apoptosis|negative regulation of death receptor-mediated apoptosis|downregulation of death receptor-mediated apoptosis						lb	2013-04-03T07:17:04Z						biological_process											owl:Class	
GO:1904400	biolink:NamedThing	response to Thyroid stimulating hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.	got7fsn_ti							sl	2015-06-23T20:57:53Z						biological_process											owl:Class	
GO:2001170	biolink:NamedThing	negative regulation of ATP biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.	got7fsn_ti	negative regulation of ATP anabolism|negative regulation of ATP synthesis|negative regulation of ATP formation|negative regulation of ATP biosynthesis|negative regulation of ATP regeneration						kmv	2011-10-26T03:18:13Z						biological_process											owl:Class	
GO:1903210	biolink:NamedThing	glomerular visceral epithelial cell apoptotic process	Any apoptotic process in a glomerular visceral epithelial cell.	got7fsn_ti	glomerular visceral epithelial cell apoptosis|glomerular podocyte apoptotic process|podocyte apoptotic process|glomerular podocyte apoptosis|podocyte apoptosis						sl	2014-07-23T17:07:55Z						biological_process											owl:Class	
GO:0060678	biolink:NamedThing	dichotomous subdivision of terminal units involved in ureteric bud branching	The process in which a ureteric bud bifurcates at its end.	got7fsn_ti	bifid subdivision of terminal units involved in ureteric bud branching						dph	2009-06-02T02:18:17Z						biological_process											owl:Class	
GO:1905619	biolink:NamedThing	regulation of alpha-(1->3)-fucosyltransferase activity	Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.	got7fsn_ti	regulation of alpha-(1,3)-fucosyltransferase activity|regulation of alpha-1,3-fucosyltransferase activity|regulation of alpha(1,3)-fucosyltransferase activity						rz	2016-10-28T14:39:37Z						biological_process											owl:Class	
GO:0046279	biolink:NamedThing	3,4-dihydroxybenzoate biosynthetic process	The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate.	got7fsn_ti	protocatechuate synthesis|protocatechuate biosynthetic process|protocatechuate formation|protocatechuate anabolism|protocatechuate biosynthesis													biological_process											owl:Class	
GO:0031605	biolink:NamedThing	obsolete ER proteasome core complex, alpha-subunit complex	OBSOLETE. The subunits forming the outer ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell.	got7fsn_ti					This term was made obsolete because there is no evidence in the literature of its existence.					True				cellular_component											owl:Class	
GO:0010711	biolink:NamedThing	negative regulation of collagen catabolic process	Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.	got7fsn_ti	downregulation of collagen catabolic process|inhibition of collagen catabolic process|negative regulation of collagen degradation|down regulation of collagen catabolic process|down-regulation of collagen catabolic process|negative regulation of collagen breakdown|negative regulation of collagen catabolism													biological_process											owl:Class	
GO:0071400	biolink:NamedThing	cellular response to oleic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.	got7fsn_ti	cellular response to oleate						mah	2009-12-11T04:40:38Z						biological_process											owl:Class	
GO:0006326	biolink:NamedThing	obsolete bent DNA binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	bent DNA binding			GO:0003681	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:0039561	biolink:NamedThing	obsolete suppression by virus of host IRF9 activity by positive regulation of IRF9 localization to nucleus	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9) by promoting the nuclear accumulation of IRF9. For example, the reovirus mu2 protein promotes nuclear accumulation of host IRF9 by an as yet unconfirmed-mechanism.	got7fsn_ti	suppression by virus of host IRF9 activity by nuclear localization of IRF9|suppression of interferon signaling by nuclear accumulation of IRF9				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-09T04:53:44Z		True				biological_process											owl:Class	
GO:1902682	biolink:NamedThing	protein localization to pericentric heterochromatin	A process in which a protein is transported to, or maintained in the pericentric heterochromatin.	got7fsn_ti	protein localization to pericentric heterochromatin|protein localisation in centromeric heterochromatin						mah	2014-02-05T16:59:30Z						biological_process											owl:Class	
GO:1901336	biolink:NamedThing	lactone biosynthetic process	The chemical reactions and pathways resulting in the formation of lactone.	got7fsn_ti	lactone anabolism|lactone biosynthesis|lactone formation|lactone synthesis						bf	2012-09-03T10:27:29Z						biological_process											owl:Class	
GO:0045813	biolink:NamedThing	positive regulation of Wnt signaling pathway, calcium modulating pathway	Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).	got7fsn_ti	up regulation of frizzled-2 signaling pathway|positive regulation of Wnt-activated signaling pathway, calcium modulating pathway|stimulation of frizzled-2 signaling pathway|up-regulation of frizzled-2 signaling pathway|positive regulation of frizzled-2 signalling pathway|upregulation of frizzled-2 signaling pathway|positive regulation of frizzled-2 signaling pathway|positive regulation of Wnt receptor signaling pathway, calcium modulating pathway|activation of frizzled-2 signaling pathway													biological_process											owl:Class	
GO:0032235	biolink:NamedThing	obsolete negative regulation of calcium ion transport via store-operated calcium channel activity	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.	got7fsn_ti	negative regulation of calcium ion transport via store-operated calcium channel activity|inhibition of calcium ion transport via store-operated calcium channel|negative regulation of store-operated calcium channel activity|down regulation of calcium ion transport via store-operated calcium channel|negative regulation of calcium transport via store-operated calcium channel|downregulation of calcium ion transport via store-operated calcium channel|down-regulation of calcium ion transport via store-operated calcium channel				This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0015279				True				biological_process											owl:Class	
GO:0033050	biolink:NamedThing	clavulanic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.	got7fsn_ti	clavulanic acid formation|clavulanic acid synthesis|clavulanic acid biosynthesis|clavulanic acid anabolism											Wikipedia:Clavulanic_acid		biological_process											owl:Class	
GO:0099100	biolink:NamedThing	G-protein gated cation channel activity	A cation channel activity that is gated by binding of a G-protein beta-gamma dimer.	got7fsn_ti														molecular_function											owl:Class	
GO:0006387	biolink:NamedThing	obsolete snRNA capping	OBSOLETE. The sequence of enzymatic reactions resulting in the addition of a cap to the 5' end of a nascent snRNA transcript.	got7fsn_ti	snRNA capping				This term was made obsolete because it has been replaced with a more specific term to describe cap hypermethylation. All RNA polymerase II transcripts receive a 7-methyl-G cap. Then for (at least) small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs), the 7-methyl-G cap is hypermethylated to become a 2,2,7-trimethylguanosine (TMG) cap.	GO:0036261				True				biological_process											owl:Class	
GO:1902331	biolink:NamedThing	obsolete DNA strand elongation involved in bacterial-type DNA replication	OBSOLETE. Any DNA strand elongation that is involved in bacterial-type DNA replication.	got7fsn_ti					This term was obsoleted because it does not represent a distinct function from its parent, DNA strand elongation involved in DNA replication.		jl	2013-07-25T10:48:26Z		True				biological_process											owl:Class	
GO:0052233	biolink:NamedThing	obsolete positive aerotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive aerotaxis within other organism during symbiotic interaction|positive aerotaxis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:2000168	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in neural tube closure	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.	got7fsn_ti							dph	2010-10-05T01:08:56Z						biological_process											owl:Class	
CHEBI:326268	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900397	biolink:NamedThing	regulation of pyrimidine nucleotide biosynthetic process	Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.	got7fsn_ti	regulation of pyrimidine nucleotide anabolism|regulation of pyrimidine nucleotide biosynthesis|regulation of pyrimidine nucleotide synthesis|regulation of pyrimidine nucleotide formation						jh	2012-04-19T01:05:31Z						biological_process											owl:Class	
GO:1990214	biolink:NamedThing	obsolete negative regulation by symbiont of host protein levels	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it is a readout, and annotations should be made to more informative terms.		ml	2013-10-10T15:39:45Z		True				biological_process											owl:Class	
GO:0048550	biolink:NamedThing	negative regulation of pinocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.	got7fsn_ti	down regulation of pinocytosis|down-regulation of pinocytosis|downregulation of pinocytosis|inhibition of pinocytosis													biological_process											owl:Class	
GO:0043462	biolink:NamedThing	regulation of ATPase activity	Any process that modulates the rate of ATP hydrolysis by an ATPase.	got7fsn_ti	regulation of adenosinetriphosphatase activity													biological_process											owl:Class	
GO:2000794	biolink:NamedThing	regulation of epithelial cell proliferation involved in lung morphogenesis	Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.	got7fsn_ti							pr	2011-06-25T07:22:38Z						biological_process											owl:Class	
GO:1900064	biolink:NamedThing	positive regulation of peroxisome organization	Any process that activates or increases the frequency, rate or extent of peroxisome organization.	got7fsn_ti	activation of peroxisome organization|up regulation of peroxisome organization|up regulation of peroxisome organisation|up-regulation of peroxisome organisation|positive regulation of peroxisome organization and biogenesis|activation of peroxisome organization and biogenesis|upregulation of peroxisome organization and biogenesis|up-regulation of peroxisome organization|upregulation of peroxisome organisation|up-regulation of peroxisome-assembly ATPase activity|upregulation of peroxisome-assembly ATPase activity|up regulation of peroxisome organization and biogenesis|up-regulation of peroxisome organization and biogenesis|positive regulation of peroxisome organisation|activation of peroxisome organisation|positive regulation of peroxisome-assembly ATPase activity|up regulation of peroxisome-assembly ATPase activity|upregulation of peroxisome organization|activation of peroxisome-assembly ATPase activity						dph	2012-01-26T01:49:09Z						biological_process											owl:Class	
GO:0070760	biolink:NamedThing	positive regulation of interleukin-35-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.	got7fsn_ti	positive regulation of interleukin-35-mediated signalling pathway|positive regulation of IL-35-mediated signaling pathway						mah	2009-06-23T02:06:16Z						biological_process											owl:Class	
GO:0070634	biolink:NamedThing	transepithelial ammonium transport	The directed movement of ammonium ions from one side of an epithelium to the other.	got7fsn_ti							mah	2009-05-06T03:34:43Z						biological_process											owl:Class	
GO:1904240	biolink:NamedThing	negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.	got7fsn_ti	downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|inhibition of VCP-NPL4-UFD1 AAA ATPase complex assembly|inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|down regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|down regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|down regulation of p97-Ufd1-Npl4 complex assembly|negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|downregulation of p97-Ufd1-Npl4 complex assembly|down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|inhibition of p97-Ufd1-Npl4 complex formation|negative regulation of p97-Ufd1-Npl4 complex assembly|downregulation of VCP-NPL4-UFD1 AAA ATPase complex formation|down-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|down-regulation of p97-Ufd1-Npl4 complex assembly|inhibition of p97-Ufd1-Npl4 complex assembly|down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|negative regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|inhibition of VCP-NPL4-UFD1 AAA ATPase complex formation|inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down regulation of p97-Ufd1-Npl4 complex formation|down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down-regulation of p97-Ufd1-Npl4 complex formation|downregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|downregulation of p97-Ufd1-Npl4 complex formation|negative regulation of p97-Ufd1-Npl4 complex formation						bf	2015-05-18T09:50:27Z						biological_process											owl:Class	
GO:0042236	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000368	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903104	biolink:NamedThing	regulation of insulin receptor signaling pathway involved in determination of adult lifespan	Any process that modulates the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.	got7fsn_ti	regulation of insulin receptor signalling pathway of determination of adult lifespan|regulation of daf-2 receptor signaling pathway of determination of adult lifespan|regulation of insulin receptor signaling pathway of determination of adult lifespan						kmv	2014-06-05T20:56:06Z						biological_process											owl:Class	
GO:0018997	biolink:NamedThing	obsolete electron transfer carrier	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	electron transfer carrier				This term was made obsolete because the parent terms cover its function.	GO:0009055				True				molecular_function											owl:Class	
GO:0006680	biolink:NamedThing	glucosylceramide catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.	got7fsn_ti	glucosylceramide catabolism|glucosylceramide breakdown|glucosylceramide degradation													biological_process											owl:Class	
GO:0071871	biolink:NamedThing	response to epinephrine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.	got7fsn_ti	response to adrenaline stimulus|response to epinephrine stimulus				Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.		mah	2010-09-13T03:27:48Z						biological_process											owl:Class	
GO:0030802	biolink:NamedThing	obsolete regulation of cyclic nucleotide biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.	got7fsn_ti	regulation of cyclic nucleotide anabolism|regulation of cyclic nucleotide synthesis|regulation of cyclic nucleotide formation|regulation of cyclic nucleotide biosynthesis				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0010678	biolink:NamedThing	negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated	Any cellular process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates carried out by repression of transcription.	got7fsn_ti	negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-dependent|negative regulation of cellular carbohydrate metabolic process by transcriptional repression|negative regulation of cellular carbohydrate metabolic process by repression of transcription													biological_process											owl:Class	
GO:0043854	biolink:NamedThing	cyclic nucleotide-gated mechanosensitive ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.	got7fsn_ti	cyclic nucleotide regulated mechanosensitive ion channel|cyclic nucleotide-regulated small mechanosensitive ion channel|cyclic nucleotide-regulated mechanosensitive ion channel|cyclic nucleotide gated mechanosensitive ion channel activity|MscS|small conductance mechanosensitive ion channel													molecular_function											owl:Class	
GO:1905444	biolink:NamedThing	negative regulation of clathrin coat assembly	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly.	got7fsn_ti	down regulation of clathrin cage assembly|negative regulation of clathrin cage assembly|down regulation of clathrin coat assembly|downregulation of clathrin cage assembly|inhibition of clathrin coat assembly|downregulation of clathrin coat assembly|inhibition of clathrin cage assembly|down-regulation of clathrin coat assembly|down-regulation of clathrin cage assembly						bf	2016-09-15T14:38:30Z						biological_process											owl:Class	
GO:0100003	biolink:NamedThing	obsolete positive regulation of sodium ion transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sodium ion transport.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0014712	biolink:NamedThing	positive regulation of branchiomeric skeletal muscle development	Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:1903393	biolink:NamedThing	positive regulation of adherens junction organization	Any process that activates or increases the frequency, rate or extent of adherens junction organization.	got7fsn_ti	up regulation of adherens junction organisation|upregulation of adherens junction assembly and maintenance|up-regulation of adherens junction assembly and maintenance|positive regulation of adherens junction organisation|up regulation of adherens junction organization|up-regulation of adherens junction organization|activation of adherens junction organization|upregulation of adherens junction organization|activation of adherens junction assembly and maintenance|upregulation of adherens junction organisation|up-regulation of adherens junction organisation|up regulation of adherens junction assembly and maintenance|positive regulation of adherens junction assembly and maintenance|activation of adherens junction organisation						als	2014-08-27T10:08:55Z						biological_process											owl:Class	
GO:0048252	biolink:NamedThing	lauric acid metabolic process	The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.	got7fsn_ti	n-dodecanoic acid metabolism|n-dodecanoic acid metabolic process|lauric acid metabolism													biological_process											owl:Class	
GO:1904817	biolink:NamedThing	serous membrane development	The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure.	got7fsn_ti	wall of serous sac development|tunica serosa development|serosa development						dph	2015-11-17T19:00:01Z						biological_process											owl:Class	
GO:0045689	biolink:NamedThing	negative regulation of antipodal cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation.	got7fsn_ti	downregulation of antipodal cell differentiation|down regulation of antipodal cell differentiation|down-regulation of antipodal cell differentiation|inhibition of antipodal cell differentiation													biological_process											owl:Class	
GO:0033495	biolink:NamedThing	ferulate biosynthetic process	The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.	got7fsn_ti	ferulate synthesis|ferulate formation|ferulate anabolism|ferulate biosynthesis											MetaCyc:PWY-5168		biological_process											owl:Class	
GO:1902384	biolink:NamedThing	glycyrrhetinate metabolic process	The chemical reactions and pathways involving glycyrrhetinate.	got7fsn_ti	glycyrrhetinate metabolism						ms	2013-09-03T12:55:55Z						biological_process											owl:Class	
GO:1902573	biolink:NamedThing	positive regulation of serine-type peptidase activity	Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity.	got7fsn_ti	positive regulation of serine protease activity|activation of serine-type peptidase activity|up-regulation of serine protease activity|up regulation of serine protease activity|upregulation of serine protease activity|upregulation of serine-type peptidase activity|up regulation of serine-type peptidase activity|up-regulation of serine-type peptidase activity|activation of serine protease activity						krc	2013-12-10T18:17:16Z						biological_process											owl:Class	
GO:1905168	biolink:NamedThing	positive regulation of double-strand break repair via homologous recombination	Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.	got7fsn_ti	positive regulation of Rhp51-dependent recombinational repair|up regulation of homologous recombinational repair|up regulation of HDR|upregulation of homology-directed repair|positive regulation of HDR|upregulation of double-strand break repair via homologous recombination|upregulation of Rhp51-dependent recombinational repair|up-regulation of HDR|up-regulation of homologous recombinational repair|up-regulation of HRR|activation of homologous recombinational repair|positive regulation of Rad51-dependent recombinational repair|up regulation of homology-directed repair|positive regulation of homologous recombinational repair|activation of HRR|positive regulation of HRR|upregulation of Rad51-dependent recombinational repair|up-regulation of double-strand break repair via homologous recombination|positive regulation of homology-directed repair|activation of Rhp51-dependent recombinational repair|upregulation of HRR|upregulation of HDR|up-regulation of Rhp51-dependent recombinational repair|up regulation of double-strand break repair via homologous recombination|activation of Rad51-dependent recombinational repair|up-regulation of Rad51-dependent recombinational repair|up regulation of HRR|upregulation of homologous recombinational repair|activation of double-strand break repair via homologous recombination|activation of HDR|up-regulation of homology-directed repair|up regulation of Rhp51-dependent recombinational repair|activation of homology-directed repair|up regulation of Rad51-dependent recombinational repair						mah	2016-04-27T12:48:47Z						biological_process											owl:Class	
GO:2001175	biolink:NamedThing	positive regulation of histone H2B conserved C-terminal lysine ubiquitination	Any process that activates or increases the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.	got7fsn_ti	positive regulation of mammalian H2B K120 ubiquitination|positive regulation of budding yeast H2B K123 ubiquitination|positive regulation of fission yeast H2B K119 ubiquitination						se	2011-10-29T06:28:59Z						biological_process											owl:Class	
GO:1901163	biolink:NamedThing	regulation of trophoblast cell migration	Any process that modulates the frequency, rate or extent of trophoblast cell migration.	got7fsn_ti							vk	2012-07-19T07:53:06Z						biological_process											owl:Class	
UBERON:0001987	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000508	biolink:NamedThing	regulation of dendritic cell chemotaxis	Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.	got7fsn_ti							ebc	2011-03-22T10:21:38Z						biological_process											owl:Class	
UBERON:0002352	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900979	biolink:NamedThing	positive regulation of tatiopterin metabolic process	Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process.	got7fsn_ti	up-regulation of tatiopterin metabolic process|activation of tatiopterin metabolic process|up regulation of tatiopterin metabolic process|up regulation of tatiopterin metabolism|up-regulation of tatiopterin metabolism|upregulation of tatiopterin metabolic process|positive regulation of tatiopterin metabolism|activation of tatiopterin metabolism|upregulation of tatiopterin metabolism						tt	2012-06-14T04:03:37Z						biological_process											owl:Class	
GO:0045307	biolink:NamedThing	obsolete activator of the establishment of competence for transformation activity	OBSOLETE. Activates the establishment of competence for transformation.	got7fsn_ti	activator of the establishment of competence for transformation activity			GO:0045809	This term was made obsolete because it does not represent a true function.					True				molecular_function											owl:Class	
GO:2001021	biolink:NamedThing	negative regulation of response to DNA damage stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage stimulus.	got7fsn_ti	negative regulation of cellular DNA damage response|negative regulation of cellular response to DNA damage stimulus|negative regulation of response to genotoxic stress|negative regulation of DNA damage response						yaf	2011-08-19T10:20:29Z						biological_process											owl:Class	
GO:1903086	biolink:NamedThing	negative regulation of sinapate ester biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis.	got7fsn_ti	down-regulation of sinapate ester synthesis|negative regulation of sinapate ester formation|negative regulation of sinapate ester synthesis|inhibition of sinapate ester biosynthesis|inhibition of sinapate ester formation|down-regulation of sinapate ester biosynthetic process|downregulation of sinapate ester anabolism|down regulation of sinapate ester anabolism|down-regulation of sinapate ester biosynthesis|down-regulation of sinapate ester anabolism|down regulation of sinapate ester formation|downregulation of sinapate ester synthesis|inhibition of sinapate ester anabolism|negative regulation of sinapate ester anabolism|downregulation of sinapate ester biosynthetic process|negative regulation of sinapate ester biosynthesis|down regulation of sinapate ester synthesis|downregulation of sinapate ester formation|down regulation of sinapate ester biosynthesis|inhibition of sinapate ester synthesis|downregulation of sinapate ester biosynthesis|down-regulation of sinapate ester formation|down regulation of sinapate ester biosynthetic process|inhibition of sinapate ester biosynthetic process						tb	2014-05-30T22:00:18Z						biological_process											owl:Class	
GO:0120244	biolink:NamedThing	terminal acetylenic compound metabolic process	The chemical reactions and pathways involving a terminal acetylenic compound, involving a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.	got7fsn_ti	terminal alkyne substituted compound metabolic process|terminal alkyne substituted compound metabolism	https://github.com/geneontology/go-ontology/issues/19842					krc	2020-08-17T22:41:12Z						biological_process											owl:Class	
GO:0008931	biolink:NamedThing	obsolete murein DD-endopeptidase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	murein DD-endopeptidase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0033034	biolink:NamedThing	positive regulation of myeloid cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.	got7fsn_ti	upregulation of myeloid cell apoptosis|activation of myeloid cell apoptosis|up-regulation of myeloid cell apoptosis|up regulation of myeloid cell apoptosis|stimulation of myeloid cell apoptosis|positive regulation of myeloid cell apoptosis													biological_process											owl:Class	
GO:1905850	biolink:NamedThing	positive regulation of forward locomotion	Any process that activates or increases the frequency, rate or extent of forward locomotion.	got7fsn_ti	up regulation of forward locomotion|activation of forward locomotion|upregulation of forward locomotion|up-regulation of forward locomotion						rz	2017-01-23T11:04:05Z						biological_process											owl:Class	
GO:0010747	biolink:NamedThing	positive regulation of long-chain fatty acid import across plasma membrane	Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	positive regulation of plasma membrane long-chain fatty acid transport													biological_process											owl:Class	
GO:0046170	biolink:NamedThing	methanol catabolic process	The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.	got7fsn_ti	methanol catabolism|methanol breakdown|methanol degradation													biological_process											owl:Class	
GO:1904095	biolink:NamedThing	negative regulation of endosperm development	Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development.	got7fsn_ti	down-regulation of endosperm development|downregulation of endosperm development|down regulation of endosperm development|inhibition of endosperm development						tb	2015-03-26T22:07:25Z						biological_process											owl:Class	
GO:0016129	biolink:NamedThing	phytosteroid biosynthetic process	The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.	got7fsn_ti	phytosteroid synthesis|phytosteroid biosynthesis|phytosteroid anabolism|phytosteroid formation													biological_process											owl:Class	
GO:1900787	biolink:NamedThing	naphtho-gamma-pyrone biosynthetic process	The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.	got7fsn_ti	naphtho-gamma-pyrone formation|naphtho-gamma-pyrone synthesis|naphtho-gamma-pyrones biosynthesis|naphtho-gamma-pyrones synthesis|naphtho-gamma-pyrones anabolism|naphtho-gamma-pyrones formation|naphtho-gamma-pyrone anabolism|naphtho-gamma-pyrone biosynthesis|naphtho-gamma-pyrones biosynthetic process						di	2012-06-04T09:36:02Z						biological_process											owl:Class	
GO:1903812	biolink:NamedThing	L-serine import across plasma membrane	The directed movement of L-serine into a cell.	got7fsn_ti	L-serine import into cell						mah	2015-01-16T14:36:29Z						biological_process											owl:Class	
GO:1902323	biolink:NamedThing	negative regulation of methyl-branched fatty acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.	got7fsn_ti	inhibition of methyl-branched fatty acid formation|negative regulation of methyl-branched fatty acid formation|down regulation of methyl-branched fatty acid synthesis|down-regulation of methyl-branched fatty acid biosynthesis|downregulation of methyl-branched fatty acid formation|down regulation of methyl-branched fatty acid biosynthetic process|down regulation of methyl-branched fatty acid anabolism|down-regulation of methyl-branched fatty acid biosynthetic process|negative regulation of methyl-branched fatty acid biosynthesis|inhibition of methyl-branched fatty acid biosynthesis|downregulation of methyl-branched fatty acid biosynthesis|inhibition of methyl-branched fatty acid biosynthetic process|downregulation of methyl-branched fatty acid anabolism|down-regulation of methyl-branched fatty acid anabolism|down-regulation of methyl-branched fatty acid synthesis|down regulation of methyl-branched fatty acid formation|negative regulation of methyl-branched fatty acid anabolism|down regulation of methyl-branched fatty acid biosynthesis|inhibition of methyl-branched fatty acid anabolism|negative regulation of methyl-branched fatty acid synthesis|down-regulation of methyl-branched fatty acid formation|downregulation of methyl-branched fatty acid biosynthetic process|inhibition of methyl-branched fatty acid synthesis|downregulation of methyl-branched fatty acid synthesis						kmv	2013-07-24T20:15:23Z						biological_process											owl:Class	
GO:2000318	biolink:NamedThing	positive regulation of T-helper 17 type immune response	Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.	got7fsn_ti	positive regulation of Th17 immune response						mah	2011-01-18T01:33:24Z						biological_process											owl:Class	
GO:0007553	biolink:NamedThing	regulation of ecdysteroid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.	got7fsn_ti	regulation of ecdysteroid metabolism													biological_process											owl:Class	
GO:2000120	biolink:NamedThing	positive regulation of sodium-dependent phosphate transport	Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport.	got7fsn_ti							jl	2010-09-23T01:35:06Z						biological_process											owl:Class	
GO:0051999	biolink:NamedThing	mannosyl-inositol phosphorylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.	got7fsn_ti	mannosyl-inositol phosphorylceramide synthesis|MIPC biosynthetic process|mannose-inositol-P-ceramide (MIPC) biosynthetic process|mannose inositol phosphoceramide biosynthetic process|mannosyl-inositol phosphorylceramide biosynthesis|mannosyl-inositol phosphorylceramide anabolism|mannosyl-inositol phosphorylceramide formation						ai	2010-07-20T10:16:26Z						biological_process											owl:Class	
GO:0110031	biolink:NamedThing	negative regulation of G2/MI transition of meiotic cell cycle	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.	got7fsn_ti							kmv	2017-07-12T20:36:35Z						biological_process											owl:Class	
GO:0061478	biolink:NamedThing	response to platelet aggregation inhibitor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.	got7fsn_ti							dph	2012-11-07T09:09:37Z						biological_process											owl:Class	
GO:1900635	biolink:NamedThing	heptadecane metabolic process	The chemical reactions and pathways involving heptadecane.	got7fsn_ti	heptadecane metabolism						tt	2012-05-21T07:05:01Z						biological_process											owl:Class	
GO:1904372	biolink:NamedThing	positive regulation of protein localization to actin cortical patch	Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch.	got7fsn_ti	upregulation of protein localization to actin cortical patch|up regulation of protein localisation to actin cortical patch|activation of protein localisation to actin cortical patch|positive regulation of protein localisation to actin cortical patch|up-regulation of protein localisation to actin cortical patch|activation of protein localization to actin cortical patch|up-regulation of protein localization to actin cortical patch|up regulation of protein localization to actin cortical patch|upregulation of protein localisation to actin cortical patch						sl	2015-06-18T22:23:43Z						biological_process											owl:Class	
GO:0045477	biolink:NamedThing	regulation of nurse cell apoptotic process	Any process that modulates the frequency, rate or extent of nurse cell apoptotic process.	got7fsn_ti	regulation of nurse cell apoptosis													biological_process											owl:Class	
GO:0005679	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045847	biolink:NamedThing	negative regulation of nitrogen utilization	Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization.	got7fsn_ti	inhibition of nitrogen utilization|downregulation of nitrogen utilization|down-regulation of nitrogen utilization|down regulation of nitrogen utilization													biological_process											owl:Class	
GO:0046641	biolink:NamedThing	positive regulation of alpha-beta T cell proliferation	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation.	got7fsn_ti	up-regulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T-lymphocyte proliferation|stimulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T-cell proliferation|positive regulation of alpha-beta T lymphocyte proliferation|up regulation of alpha-beta T cell proliferation|activation of alpha-beta T cell proliferation|upregulation of alpha-beta T cell proliferation													biological_process											owl:Class	
GO:0039533	biolink:NamedThing	regulation of MDA-5 signaling pathway	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.	got7fsn_ti	regulation of MDA-5 signalling pathway|regulation of IFIH1 signaling pathway|regulation of melanoma differentiation-associated gene 5 signaling pathway|regulation of MDA5 signaling pathway						bf	2012-01-03T11:17:31Z						biological_process											owl:Class	
GO:0008548	biolink:NamedThing	obsolete signal-recognition-particle GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Activity is associated with the signal-recognition particle, a protein and RNA-containing structure involved in endoplasmic reticulum-associated protein synthesis.	got7fsn_ti	signal-recognition-particle GTPase activity				This term was made obsolete because it represents a gene product.	GO:0005786|GO:0003924				True				molecular_function											owl:Class	
CHEBI:24043	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900036	biolink:NamedThing	positive regulation of cellular response to heat	Any process that activates or increases the frequency, rate or extent of cellular response to heat.	got7fsn_ti	activation of cellular response to heat|up regulation of cellular response to heat|positive regulation of cellular response to heat stress|activation of cellular response to heat stress|up regulation of cellular response to heat stress|up-regulation of cellular response to heat|upregulation of cellular response to heat|up-regulation of cellular response to heat stress|upregulation of cellular response to heat stress						yaf	2012-01-17T09:27:47Z						biological_process											owl:Class	
GO:1904687	biolink:NamedThing	positive regulation of mitotic spindle disassembly	Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly.	got7fsn_ti	up-regulation of spindle disassembly during mitosis|activation of spindle degradation during mitosis|positive regulation of mitotic spindle breakdown|positive regulation of mitotic spindle catabolism|activation of mitotic spindle disassembly|activation of spindle disassembly during mitosis|up-regulation of spindle degradation during mitosis|up-regulation of mitotic spindle degradation|up-regulation of spindle breakdown during mitosis|upregulation of spindle breakdown during mitosis|up-regulation of mitotic spindle disassembly|up regulation of spindle disassembly during mitosis|up regulation of spindle degradation during mitosis|upregulation of mitotic spindle degradation|up-regulation of mitotic spindle breakdown|upregulation of mitotic spindle catabolism|positive regulation of spindle degradation during mitosis|positive regulation of spindle breakdown during mitosis|up regulation of mitotic spindle degradation|positive regulation of spindle disassembly during mitosis|activation of spindle breakdown during mitosis|upregulation of mitotic spindle breakdown|activation of mitotic spindle breakdown|up regulation of spindle breakdown during mitosis|activation of mitotic spindle catabolism|upregulation of spindle degradation during mitosis|upregulation of spindle disassembly during mitosis|up regulation of mitotic spindle catabolism|up regulation of mitotic spindle breakdown|up-regulation of mitotic spindle catabolism|activation of mitotic spindle degradation|up regulation of mitotic spindle disassembly|upregulation of mitotic spindle disassembly|positive regulation of mitotic spindle degradation						al	2015-09-24T14:20:13Z						biological_process											owl:Class	
GO:1900000	biolink:NamedThing	regulation of anthocyanin catabolic process	Any process that modulates the frequency, rate or extent of anthocyanin catabolic process.	got7fsn_ti	regulation of anthocyanin breakdown|regulation of anthocyanin degradation|regulation of anthocyanin catabolism						tb	2011-12-20T07:12:07Z						biological_process											owl:Class	
GO:0045557	biolink:NamedThing	obsolete TRAIL receptor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.	got7fsn_ti	TRAIL receptor formation|TRAIL receptor synthesis|TRAIL receptor anabolism|TRAIL receptor biosynthesis	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1901924	biolink:NamedThing	positive regulation of sclerotium development	Any process that activates or increases the frequency, rate or extent of sclerotium development.	got7fsn_ti	upregulation of sclerotium development|up regulation of sclerotium development|activation of sclerotium development|up-regulation of sclerotium development						di	2013-02-15T20:00:28Z						biological_process											owl:Class	
GO:1903687	biolink:NamedThing	negative regulation of border follicle cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration.	got7fsn_ti	inhibition of border follicle cell migration						als	2014-12-01T13:41:05Z						biological_process											owl:Class	
GO:0004874	biolink:NamedThing	obsolete aryl hydrocarbon receptor activity	OBSOLETE. Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16732			This term was obsoleted because it represents a gene product.					True				molecular_function											owl:Class	
GO:0007106	biolink:NamedThing	obsolete cytokinesis, protein recruitment	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytokinesis, protein recruitment				This term was made obsolete because it was not defined.					True				biological_process											owl:Class	
GO:0030545	biolink:NamedThing	signaling receptor regulator activity	Binds to and modulates the activity of a receptor.	got7fsn_ti	receptor regulator activity													molecular_function											owl:Class	
GO:1905491	biolink:NamedThing	positive regulation of sensory neuron axon guidance	Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance.	got7fsn_ti	up-regulation of sensory neuron axon guidance|upregulation of sensory neuron axon guidance|up regulation of sensory neuron axon guidance|activation of sensory neuron axon guidance						hbye	2016-09-23T13:19:12Z						biological_process											owl:Class	
GO:0051314	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0009470	biolink:NamedThing	obsolete class IIa cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	class IIa cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0060642	biolink:NamedThing	white fat cell differentiation involved in mammary gland fat development	The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.	got7fsn_ti							dph	2009-05-27T05:50:56Z						biological_process											owl:Class	
CL:0000487	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000007	biolink:NamedThing	negative regulation of metanephric comma-shaped body morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.	got7fsn_ti							jl	2010-07-30T02:17:17Z						biological_process											owl:Class	
GO:0002382	biolink:NamedThing	regulation of tissue kallikrein-kinin cascade	Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade.	got7fsn_ti	regulation of glandular kallikrein-kinin cascade													biological_process											owl:Class	
GO:1900918	biolink:NamedThing	negative regulation of octadecene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process.	got7fsn_ti	inhibition of octadecene metabolic process|inhibition of octadecene metabolism|downregulation of octadecene metabolism|downregulation of octadecene metabolic process|down regulation of octadecene metabolic process|down-regulation of octadecene metabolism|down regulation of octadecene metabolism|down-regulation of octadecene metabolic process|negative regulation of octadecene metabolism						tt	2012-06-13T04:26:34Z						biological_process											owl:Class	
CHEBI:29967	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016550	biolink:NamedThing	obsolete insertion or deletion editing	OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during or after transcription.	got7fsn_ti	insertion/deletion editing|insertion or deletion editing				This term was made obsolete because it represents two separate processes (insertion and deletion).	GO:0070705|GO:0070706				True				biological_process											owl:Class	
GO:2000976	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in detection of glucose	OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in detection of glucose.	got7fsn_ti	regulation of global transcription from Pol II promoter involved in glucose sensing|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose detection|regulation of transcription from RNA polymerase II promoter, global involved in detection of glucose|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose sensing|regulation of transcription from RNA polymerase II promoter, global involved in glucose detection|global transcription regulation from Pol II promoter involved in glucose perception|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose perception|regulation of gene-specific transcription from RNA polymerase II promoter involved in detection of glucose|regulation of transcription from RNA polymerase II promoter involved in glucose sensing|global transcription regulation from Pol II promoter involved in detection of glucose|regulation of transcription from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter, global involved in glucose sensing|regulation of transcription from RNA polymerase II promoter involved in glucose perception|global transcription regulation from Pol II promoter involved in glucose detection|regulation of global transcription from Pol II promoter involved in detection of glucose|global transcription regulation from Pol II promoter involved in glucose sensing|regulation of global transcription from Pol II promoter involved in glucose detection|regulation of transcription from Pol II promoter involved in glucose detection|regulation of transcription from Pol II promoter involved in glucose sensing|regulation of transcription from RNA polymerase II promoter involved in glucose detection|regulation of transcription from RNA polymerase II promoter, global involved in glucose perception|regulation of global transcription from Pol II promoter involved in glucose perception|regulation of transcription from Pol II promoter involved in detection of glucose				This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization.	GO:0006357|GO:0051594	vk	2011-08-02T05:06:52Z		True				biological_process											owl:Class	
GO:1902308	biolink:NamedThing	regulation of peptidyl-serine dephosphorylation	Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation.	got7fsn_ti							rl	2013-07-19T10:34:59Z						biological_process											owl:Class	
GO:0046432	biolink:NamedThing	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process	The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.	got7fsn_ti	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolism													biological_process											owl:Class	
GO:0097175	biolink:NamedThing	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.	got7fsn_ti	1,6-anhydro-N-acetylmuramic acid breakdown|1,6-anhydro-N-acetylmuramic acid catabolic process|1,6-anhydro-N-acetylmuramate breakdown|1,6-anhydro-N-acetyl-beta-muramic acid breakdown|1,6-anhydro-N-acetyl-beta-muramate catabolic process|1,6-anhydro-N-acetylmuramate catabolism|1,6-anhydro-N-acetyl-beta-muramate breakdown|1,6-anhydro-N-acetylmuramate catabolic process|1,6-anhydro-N-acetylmuramic acid degradation|1,6-anhydro-N-acetyl-beta-muramic acid catabolism|1,6-anhydro-N-acetyl-beta-muramic acid degradation|1,6-anhydro-N-acetylmuramate degradation|1,6-anhydro-N-acetylmuramic acid catabolism|1,6-anhydro-N-acetyl-beta-muramate catabolism|1,6-anhydro-N-acetyl-beta-muramate degradation						pr	2011-10-07T12:58:32Z						biological_process											owl:Class	
GO:0090521	biolink:NamedThing	glomerular visceral epithelial cell migration	The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.	got7fsn_ti	podocyte cell migration						tb	2013-01-08T11:08:57Z						biological_process											owl:Class	
GO:0000061	biolink:NamedThing	obsolete protein import into nucleus, substrate release	OBSOLETE. A protein complex disassembly process that contributes to protein import into the nucleus, and that results in the dissociation of the cargo protein and the carrier (such as an importin alpha/beta heterodimer) from each other and from the nuclear pore complex.	got7fsn_ti	protein transport from cytoplasm to nucleus, substrate release|protein substrate release during protein transport from cytoplasm to nucleus|protein import into cell nucleus, substrate release|protein-nucleus import, substrate release|protein substrate release during protein-nucleus import|protein substrate release during protein import into nucleus				This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True				biological_process											owl:Class	
GO:0042427	biolink:NamedThing	serotonin biosynthetic process	The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	got7fsn_ti	serotonin anabolism|serotonin biosynthesis|serotonin synthesis|serotonin formation											Wikipedia:Serotonin		biological_process											owl:Class	
GO:1990645	biolink:NamedThing	obsolete phosphorylase dephosphorylation	OBSOLETE. The modification of phosphorylases by removal of phosphate groups.	got7fsn_ti	phosphorylase dephosphorylation				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-02-18T16:39:50Z		True				biological_process											owl:Class	
GO:0002615	biolink:NamedThing	positive regulation of monocyte antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.	got7fsn_ti	upregulation of monocyte antigen processing and presentation|activation of monocyte antigen processing and presentation|stimulation of monocyte antigen processing and presentation|up regulation of monocyte antigen processing and presentation|up-regulation of monocyte antigen processing and presentation													biological_process											owl:Class	
GO:0046808	biolink:NamedThing	obsolete assemblon	OBSOLETE. Antigenically dense structures located at the periphery of nuclei, close to but not abutting nuclear membranes. Assemblons contain the proteins for immature-capsid assembly; they are located at the periphery of a diffuse structure composed of proteins involved in DNA synthesis, which overlaps only minimally with the assemblons. More than one site can be present simultaneously.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20746			This term was obsoleted because it does not correspond to a real cellular component, but to a site of immunoreactivity.					True				cellular_component											owl:Class	
GO:0016187	biolink:NamedThing	obsolete synaptic vesicle internalization	OBSOLETE. Internalization of the contents of a synaptic vesicle into the postsynaptic membrane following endocytosis.	got7fsn_ti	synaptic vesicle internalization				This term was made obsolete because it was wrongly defined.	GO:0016192				True				biological_process											owl:Class	
GO:1901383	biolink:NamedThing	negative regulation of chorionic trophoblast cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation.	got7fsn_ti	downregulation of chorionic trophoblast cell proliferation|down regulation of chorionic trophoblast cell proliferation|down-regulation of chorionic trophoblast cell proliferation|inhibition of chorionic trophoblast cell proliferation						vk	2012-10-01T10:04:23Z						biological_process											owl:Class	
GO:1902887	biolink:NamedThing	obsolete positive regulation of proteasome-activating ATPase activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity.	got7fsn_ti	upregulation of ATPase involved in positive regulation of proteasomal protein catabolic process|up regulation of proteasomal ATPase activity|positive regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|upregulation of proteasome-activating ATPase activity|activation of proteasomal ATPase activity|positive regulation of proteasomal ATPase activity|up-regulation of proteasomal ATPase activity|activation of proteasome channel gating activity|upregulation of proteasome channel gating activity|upregulation of proteasomal ATPase activity|activation of proteasome-activating ATPase activity|up-regulation of proteasome channel gating activity|up regulation of proteasome-activating ATPase activity|positive regulation of proteasome channel gating activity|upregulation of proteasome channel opening activity|up regulation of proteasome channel opening activity|activation of ATPase involved in positive regulation of proteasomal protein catabolic process|up regulation of proteasome channel gating activity|up-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|up-regulation of proteasome-activating ATPase activity|positive regulation of proteasome channel opening activity|up-regulation of proteasome channel opening activity|up regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|activation of proteasome channel opening activity	https://github.com/geneontology/go-ontology/issues/20879			This term was obsoleted because it represents a molecular function.		di	2014-04-04T17:35:36Z		True				biological_process											owl:Class	
GO:0071449	biolink:NamedThing	cellular response to lipid hydroperoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.	got7fsn_ti	cellular response to LHPO						mah	2009-12-16T04:17:57Z						biological_process											owl:Class	
GO:0052503	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the symbiont calcium-dependent protein kinase pathway during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway|positive regulation of defense-related symbiont CDPK pathway by organism				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:2000150	biolink:NamedThing	regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.	got7fsn_ti							dph	2010-10-01T07:11:11Z						biological_process											owl:Class	
GO:0001954	biolink:NamedThing	positive regulation of cell-matrix adhesion	Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.	got7fsn_ti	stimulation of cell-matrix adhesion|up-regulation of cell-matrix adhesion|upregulation of cell-matrix adhesion|up regulation of cell-matrix adhesion|activation of cell-matrix adhesion													biological_process											owl:Class	
GO:0110045	biolink:NamedThing	negative regulation of cell cycle switching, mitotic to meiotic cell cycle	Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.	got7fsn_ti							kmv	2017-08-08T21:33:28Z						biological_process											owl:Class	
GO:0075186	biolink:NamedThing	negative regulation of infection cushion formation	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of infection cushion formation on or near host													biological_process											owl:Class	
GO:0001084	biolink:NamedThing	obsolete transcription factor activity, TFIID-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIID class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	got7fsn_ti	TFIID-class binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001094	krc	2010-10-27T04:15:22Z		True				molecular_function											owl:Class	
GO:0039541	biolink:NamedThing	obsolete suppression by virus of host RIG-I via RIG-I binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of RIG-I (also known as DDX58) by binding to RIG-I itself.	got7fsn_ti	inhibition by virus of host DDX58:MAVS binding				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-19T02:14:20Z		True				biological_process											owl:Class	
GO:0007100	biolink:NamedThing	mitotic centrosome separation	Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.	got7fsn_ti														biological_process											owl:Class	
GO:0060103	biolink:NamedThing	obsolete collagen and cuticulin-based cuticle extracellular matrix part	OBSOLETE. Any constituent part of the collagen and cuticulin-based cuticle extracellular matrix, a collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0060102				True				cellular_component											owl:Class	
GO:0052106	biolink:NamedThing	obsolete quorum sensing involved in interaction with host	OBSOLETE. The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	quorum sensing during interaction with host				The reason for obsoletion is that this term was not clearly defined and usage was inconsistent.					True				biological_process											owl:Class	
GO:0070658	biolink:NamedThing	neuromast hair cell differentiation involved in neuromast regeneration	Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury.	got7fsn_ti							mah	2009-05-28T04:16:27Z						biological_process											owl:Class	
GO:1905496	biolink:NamedThing	regulation of triplex DNA binding	Any process that modulates the frequency, rate or extent of triplex DNA binding.	got7fsn_ti							ans	2016-09-26T14:57:09Z						biological_process											owl:Class	
GO:0009983	biolink:NamedThing	obsolete tyrosine aminopeptidase activity	OBSOLETE. Catalysis of the release of N-terminal tyrosine from a peptide.	got7fsn_ti	tyrosine aminopeptidase activity			GO:0004177	This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.					True				molecular_function											owl:Class	
GO:1900917	biolink:NamedThing	regulation of octadecene metabolic process	Any process that modulates the frequency, rate or extent of octadecene metabolic process.	got7fsn_ti	regulation of octadecene metabolism						tt	2012-06-13T04:26:11Z						biological_process											owl:Class	
GO:1904720	biolink:NamedThing	obsolete regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	OBSOLETE. Any process that modulates the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.	got7fsn_ti	regulation of HAC1-type intron splice site recognition and cleavage|regulation of HAC1 mRNA cleavage|regulation of XBP1 mRNA cleavage|regulation of IRE1-mediated XBP-1 mRNA cleavage				The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted.	GO:1903895	bf	2015-10-08T14:52:49Z		True				biological_process											owl:Class	
GO:1904118	biolink:NamedThing	regulation of otic vesicle morphogenesis	Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis.	got7fsn_ti							pga	2015-04-07T14:00:56Z						biological_process											owl:Class	
GO:1905329	biolink:NamedThing	sphingoid long-chain base transport	The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast.	got7fsn_ti	long-chain base transport|sphingoid base(1+) transport|sphingoid transport|dihydrosphingosine transport|phytosphingosine transport|sphingosine transport						tb	2016-07-22T01:40:59Z						biological_process											owl:Class	
GO:1901358	biolink:NamedThing	beta-D-galactofuranose biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose.	got7fsn_ti	beta-D-galactofuranose formation|beta-D-galactofuranose anabolism|beta-D-galactofuranose synthesis|beta-D-galactofuranose biosynthesis						di	2012-09-13T22:19:47Z						biological_process											owl:Class	
GO:1900308	biolink:NamedThing	positive regulation of maltoheptaose transport	Any process that activates or increases the frequency, rate or extent of maltoheptaose transport.	got7fsn_ti	upregulation of maltoheptaose transport|activation of maltoheptaose transport|up-regulation of maltoheptaose transport|up regulation of maltoheptaose transport						tt	2012-04-05T07:58:35Z						biological_process											owl:Class	
GO:0002850	biolink:NamedThing	negative regulation of peripheral T cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction.	got7fsn_ti	down regulation of peripheral T cell tolerance induction|inhibition of peripheral T cell tolerance induction|down-regulation of peripheral T cell tolerance induction|downregulation of peripheral T cell tolerance induction													biological_process											owl:Class	
GO:0046419	biolink:NamedThing	octopine metabolic process	The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.	got7fsn_ti	octopine metabolism													biological_process											owl:Class	
GO:0071290	biolink:NamedThing	cellular response to platinum ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.	got7fsn_ti	cellular response to platinum						mah	2009-12-10T04:08:06Z						biological_process											owl:Class	
GO:1900314	biolink:NamedThing	positive regulation of maltohexaose transport	Any process that activates or increases the frequency, rate or extent of maltohexaose transport.	got7fsn_ti	upregulation of maltohexaose transport|activation of maltohexaose transport|up-regulation of maltohexaose transport|up regulation of maltohexaose transport						tt	2012-04-05T07:59:35Z						biological_process											owl:Class	
GO:0004374	biolink:NamedThing	obsolete glycine cleavage system	OBSOLETE. Catalysis of the reactions: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + carbon dioxide (CO2), followed by S-aminomethyldihydrolipoylprotein + (6S)-tetrahydrofolate = dihydrolipoylprotein + (6R)-5,10-methylenetetrahydrofolate + ammonia. Made up of two components, aminomethyltransferase and glycine dehydrogenase (decarboxylating).	got7fsn_ti	glycine synthase|glycine cleavage system			GO:0019464	This term was made obsolete because it represents a process rather than a function.					True				molecular_function											owl:Class	
GO:0019351	biolink:NamedThing	dethiobiotin biosynthetic process	The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms.	got7fsn_ti	dethiobiotin formation|dethiobiotin biosynthesis|desthiobiotin biosynthetic process|desthiobiotin biosynthesis|dethiobiotin anabolism|dethiobiotin synthesis													biological_process											owl:Class	
GO:0110141	biolink:NamedThing	L-glutamate import into mitochondrion	The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti							kmv	2019-04-24T19:13:46Z						biological_process											owl:Class	
GO:0003103	biolink:NamedThing	obsolete positive regulation of diuresis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of diuresis. Diuresis is the process of renal water excretion.	got7fsn_ti	positive regulation of diuresis				This term was made obsolete because its definition was inaccurate.	GO:0035810				True				biological_process											owl:Class	
GO:0052145	biolink:NamedThing	obsolete negative energy taxis on or near host	OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0016626	biolink:NamedThing	obsolete oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an acceptor other than NAD, NADP, oxygen, an iron-sulfur protein, disulphide or a cytochrome.	got7fsn_ti	oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016903				True				molecular_function											owl:Class	
GO:0120277	biolink:NamedThing	positive regulation of cerebral blood circulation	Any process that activates or increases the frequency, rate or extent of cerebral blood circulation.	got7fsn_ti	up regulation of cerebral blood circulation|activation of cerebral blood circulation|positive regulation of cerebrum blood circulation|upregulation of cerebral blood circulation|positive regulation of telencephalon blood circulation|up-regulation of cerebral blood circulation	https://github.com/geneontology/go-ontology/issues/20107					krc	2020-10-21T06:55:42Z						biological_process											owl:Class	
GO:0034619	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903369	biolink:NamedThing	negative regulation of foraging behavior	Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior.	got7fsn_ti	down regulation of foraging behavior|inhibition of foraging behavior|downregulation of foraging behavior|down-regulation of foraging behavior						mr	2014-08-22T03:03:12Z						biological_process											owl:Class	
GO:1903285	biolink:NamedThing	positive regulation of hydrogen peroxide catabolic process	Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process.	got7fsn_ti	activation of hydrogen peroxide removal|upregulation of hydrogen peroxide catabolism|up regulation of hydrogen peroxide catabolic process|positive regulation of hydrogen peroxide breakdown|upregulation of H2O2 scavenging|activation of H2O2 catabolic process|activation of hydrogen peroxide scavenging|upregulation of detoxification of hydrogen peroxide|up-regulation of hydrogen peroxide catabolic process|up-regulation of hydrogen peroxide catabolism|up regulation of hydrogen peroxide degradation|positive regulation of detoxification of hydrogen peroxide|positive regulation of hydrogen peroxide scavenging|up-regulation of hydrogen peroxide removal|up regulation of detoxification of hydrogen peroxide|positive regulation of hydrogen peroxide degradation|activation of hydrogen peroxide catabolism|up-regulation of H2O2 scavenging|upregulation of hydrogen peroxide degradation|upregulation of hydrogen peroxide catabolic process|upregulation of hydrogen peroxide removal|up-regulation of hydrogen peroxide scavenging|up-regulation of hydrogen peroxide breakdown|activation of hydrogen peroxide degradation|positive regulation of hydrogen peroxide removal|up regulation of H2O2 catabolic process|up regulation of hydrogen peroxide removal|up regulation of hydrogen peroxide catabolism|up regulation of detoxification of H2O2|positive regulation of hydrogen peroxide catabolism|activation of hydrogen peroxide catabolic process|upregulation of hydrogen peroxide scavenging|positive regulation of H2O2 scavenging|upregulation of hydrogen peroxide breakdown|upregulation of H2O2 catabolic process|up-regulation of detoxification of hydrogen peroxide|up-regulation of H2O2 catabolic process|up regulation of hydrogen peroxide breakdown|up regulation of hydrogen peroxide scavenging|positive regulation of H2O2 catabolic process|positive regulation of detoxification of H2O2|upregulation of detoxification of H2O2|activation of hydrogen peroxide breakdown|activation of detoxification of hydrogen peroxide|up-regulation of hydrogen peroxide degradation|up regulation of H2O2 scavenging|activation of detoxification of H2O2|up-regulation of detoxification of H2O2|activation of H2O2 scavenging						bf	2014-08-11T13:28:40Z						biological_process											owl:Class	
GO:0031540	biolink:NamedThing	regulation of anthocyanin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.	got7fsn_ti	regulation of anthocyanin synthesis|regulation of anthocyanin anabolism|regulation of anthocyanin biosynthesis|regulation of anthocyanin formation													biological_process											owl:Class	
GO:0100068	biolink:NamedThing	obsolete positive regulation of pyrimidine-containing compound salvage by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pyrimidine-containing compound salvage.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0120069	biolink:NamedThing	positive regulation of stomach fundus smooth muscle contraction	Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction.	got7fsn_ti							krc	2017-06-13T23:27:25Z						biological_process											owl:Class	
GO:0005805	biolink:NamedThing	obsolete ER-Golgi transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ER-Golgi transport vesicle				This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.	GO:0030134				True				cellular_component											owl:Class	
GO:0031108	biolink:NamedThing	holo-[acyl-carrier-protein] biosynthetic process	The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein].	got7fsn_ti	holo-[acyl-carrier-protein] synthesis|holo-[acyl-carrier-protein] formation|holo-[acyl-carrier-protein] anabolism|holo-[acyl-carrier-protein] biosynthesis|holo-[acyl-carrier protein] biosynthesis													biological_process											owl:Class	
GO:0070228	biolink:NamedThing	regulation of lymphocyte apoptotic process	Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.	got7fsn_ti	regulation of lymphocyte apoptosis				Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).									biological_process											owl:Class	
GO:0075268	biolink:NamedThing	regulation of aecium development	Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.	got7fsn_ti														biological_process											owl:Class	
GO:0070909	biolink:NamedThing	glutamate:gamma-aminobutyric acid antiporter activity	Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out).	got7fsn_ti	glutamate-gamma-aminobutyric acid antiporter activity|glutamate/gamma-aminobutyric acid antiporter activity|glutamate: GABA antiporter activity						mah	2009-09-04T03:51:32Z						molecular_function											owl:Class	
GO:1901438	biolink:NamedThing	negative regulation of toluene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process.	got7fsn_ti	inhibition of methylbenzene metabolism|inhibition of toluene metabolism|down regulation of toluene metabolism|negative regulation of methylbenzene metabolism|down-regulation of toluene metabolism|inhibition of methylbenzene metabolic process|down-regulation of methylbenzene metabolic process|down-regulation of methylbenzene metabolism|downregulation of methylbenzene metabolism|negative regulation of methylbenzene metabolic process|down regulation of toluene metabolic process|down-regulation of toluene metabolic process|negative regulation of toluene metabolism|downregulation of methylbenzene metabolic process|down regulation of methylbenzene metabolic process|downregulation of toluene metabolic process|inhibition of toluene metabolic process|down regulation of methylbenzene metabolism|downregulation of toluene metabolism						tt	2012-10-01T21:18:50Z						biological_process											owl:Class	
GO:0002823	biolink:NamedThing	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.	got7fsn_ti														biological_process											owl:Class	
GO:0042563	biolink:NamedThing	obsolete importin alpha-subunit nuclear export complex	OBSOLETE. A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha-subunit/CAS/Ran, and which functions to transport the importin alpha-subunit out of the nucleus through the nuclear pore.	got7fsn_ti					The reason for obsoletion is that these terms include the substrate of the reaction.					True				cellular_component											owl:Class	
GO:0090070	biolink:NamedThing	positive regulation of ribosome biogenesis	Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.	got7fsn_ti							tb	2009-09-11T10:32:17Z						biological_process											owl:Class	
GO:0030827	biolink:NamedThing	obsolete negative regulation of cGMP biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.	got7fsn_ti	inhibition of cGMP biosynthetic process|negative regulation of cGMP formation|down-regulation of cGMP biosynthetic process|negative regulation of cGMP biosynthesis|downregulation of cGMP biosynthetic process|down regulation of cGMP biosynthetic process|negative regulation of cGMP synthesis|negative regulation of cGMP anabolism				The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism.	GO:0030251				True				biological_process											owl:Class	
GO:1901228	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in heart development	Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development.	got7fsn_ti	up-regulation of global transcription from RNA polymerase II promoter involved in heart development|up-regulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of global transcription from Pol II promoter involved in cardiac development|up regulation of transcription from RNA polymerase II promoter involved in heart development|activation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of transcription from Pol II promoter involved in dorsal vessel development|upregulation of global transcription from RNA polymerase II promoter involved in heart development|stimulation of transcription from RNA polymerase II promoter involved in heart development|activation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of transcription from Pol II promoter involved in cardiac development|up regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|up-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of global transcription from Pol II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in heart development|upregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of global transcription from RNA polymerase II promoter involved in cardiac development|up regulation of global transcription from RNA polymerase II promoter involved in heart development|stimulation of global transcription from RNA polymerase II promoter involved in heart development|up regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of global transcription from RNA polymerase II promoter involved in heart development|positive regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of transcription from RNA polymerase II promoter involved in cardiac development|activation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of transcription from Pol II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription from RNA polymerase II promoter involved in cardiac development|stimulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of transcription from RNA polymerase II promoter involved in cardiac development						pr	2012-08-07T12:53:01Z						biological_process											owl:Class	
GO:0005906	biolink:NamedThing	obsolete clathrin adaptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	adaptin|clathrin adaptor			GO:0030119	This term was made obsolete because it was positioned incorrectly, so the replacement term has a definition different from what this term appeared to mean.					True				cellular_component											owl:Class	
GO:1900519	biolink:NamedThing	negative regulation of response to pullulan	Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan.	got7fsn_ti	down regulation of response to pullulan|down-regulation of response to pullulan|inhibition of response to pullulan|downregulation of response to pullulan						tt	2012-05-02T04:12:09Z						biological_process											owl:Class	
PR:000011407	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904759	biolink:NamedThing	protein localization to equatorial microtubule organizing center	A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center.	got7fsn_ti	protein localization to eMTOC|protein localisation to equatorial microtubule organizing center|protein localisation in equatorial microtubule organizing center|protein localization in equatorial microtubule organizing center						mah	2015-10-21T12:37:55Z						biological_process											owl:Class	
GO:2000429	biolink:NamedThing	negative regulation of neutrophil aggregation	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation.	got7fsn_ti	negative regulation of neutrocyte aggregation|negative regulation of neutrophilic leukocyte aggregation|negative regulation of neutrophil leucocyte aggregation						ebc	2011-02-28T05:19:28Z						biological_process											owl:Class	
GO:0008571	biolink:NamedThing	obsolete non-chaperonin molecular chaperone ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin.	got7fsn_ti	non-chaperonin molecular chaperone ATPase activity			GO:0016887	This term was made obsolete because it represents a class of gene products.	GO:0006457				True				molecular_function											owl:Class	
GO:1905929	biolink:NamedThing	obsolete positive regulation of invadopodium disassembly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium disassembly.	got7fsn_ti	up-regulation of invadopodium disassembly|up regulation of invadopodium disassembly|upregulation of invadopodium disassembly|activation of invadopodium disassembly				This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:39:14Z		True				biological_process											owl:Class	
GO:0015384	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902462	biolink:NamedThing	positive regulation of mesenchymal stem cell proliferation	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation.	got7fsn_ti	activation of MSC proliferation|activation of mesenchymal stem cell proliferation|up regulation of mesenchymal stem cell proliferation|positive regulation of MSC proliferation|upregulation of MSC proliferation|up-regulation of mesenchymal stem cell proliferation|upregulation of mesenchymal stem cell proliferation|up-regulation of MSC proliferation|up regulation of MSC proliferation						pm	2013-10-22T10:01:17Z						biological_process											owl:Class	
GO:0071639	biolink:NamedThing	positive regulation of monocyte chemotactic protein-1 production	Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1.	got7fsn_ti	positive regulation of CCL2 production|positive regulation of MCP-1 production						mah	2010-02-12T10:39:51Z						biological_process											owl:Class	
GO:2001299	biolink:NamedThing	N(omega),N(omega)-dimethyl-L-arginine catabolic process	The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.	got7fsn_ti	N(omega),N(omega)-dimethyl-L-arginine degradation|N(omega),N(omega)-dimethyl-L-arginine breakdown|N(omega),N(omega)-dimethyl-L-arginine catabolism						pr	2012-02-14T03:40:03Z						biological_process											owl:Class	
GO:0045955	biolink:NamedThing	negative regulation of calcium ion-dependent exocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis.	got7fsn_ti	downregulation of calcium ion-dependent exocytosis|down-regulation of calcium ion-dependent exocytosis|inhibition of calcium ion-dependent exocytosis|down regulation of calcium ion-dependent exocytosis													biological_process											owl:Class	
GO:0006697	biolink:NamedThing	ecdysone biosynthetic process	The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.	got7fsn_ti	ecdysone anabolism|ecdysone formation|ecdysone synthesis|ecdysone biosynthesis													biological_process											owl:Class	
GO:0016095	biolink:NamedThing	polyprenol catabolic process	The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.	got7fsn_ti	polyprenol breakdown|polyprenol catabolism|polyprenol degradation													biological_process											owl:Class	
GO:0051950	biolink:NamedThing	positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.	got7fsn_ti	upregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of GABA uptake during transmission of nerve impulse|positive regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|stimulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of 4-aminobutyrate reuptake|up-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of gamma-aminobutyric acid reuptake|positive regulation of 4-aminobutyrate uptake during transmission of nerve impulse|positive regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|activation of gamma-aminobutyric acid uptake during transmission of nerve impulse|up regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of GABA reuptake													biological_process											owl:Class	
GO:0051422	biolink:NamedThing	negative regulation of endo-1,4-beta-xylanase activity	Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.	got7fsn_ti	down-regulation of endo-1,4-beta-xylanase activity|downregulation of endo-1,4-beta-xylanase activity|endo-1,4-beta-xylanase inhibitor|down regulation of endo-1,4-beta-xylanase activity|xylanase inhibitor|inhibition of endo-1,4-beta-xylanase activity													biological_process											owl:Class	
GO:0071533	biolink:NamedThing	obsolete ankyrin repeat-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an ankyrin repeat interaction.	got7fsn_ti	ANK repeat-mediated complex assembly				This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T02:27:56Z		True				biological_process											owl:Class	
GO:2000445	biolink:NamedThing	positive regulation of toll-like receptor 21 signaling pathway	Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway.	got7fsn_ti	positive regulation of TLR21 signaling pathway|positive regulation of toll-like receptor 21 signalling pathway						bf	2011-03-04T10:33:00Z						biological_process											owl:Class	
GO:0018332	biolink:NamedThing	obsolete enzyme active site formation via O-(phospho-5'-adenosine)-L-threonine	OBSOLETE. The transient adenylylation of threonine to form N6-(phospho-5'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:19039103 and PMID:19503829.					True		RESID:AA0267		biological_process											owl:Class	
GO:0007261	biolink:NamedThing	obsolete JAK-induced STAT protein dimerization	OBSOLETE. The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases.	got7fsn_ti	JAK-induced STAT protein dimerization				This term was made obsolete because it is ambiguous, and protein dimerization is represented by molecular function terms.	GO:0046983|GO:0007260				True				biological_process											owl:Class	
GO:1902877	biolink:NamedThing	positive regulation of embryonic pattern specification	Any process that activates or increases the frequency, rate or extent of embryonic pattern specification.	got7fsn_ti	upregulation of ventral/lateral system|upregulation of embryonic pattern specification|up regulation of ventral/lateral system|up-regulation of ventral/lateral system|positive regulation of ventral/lateral system|activation of ventral/lateral system|up-regulation of embryonic pattern specification|up regulation of embryonic pattern specification|activation of embryonic pattern specification						mr	2014-04-03T15:25:26Z						biological_process											owl:Class	
GO:1905745	biolink:NamedThing	negative regulation of mRNA cis splicing, via spliceosome	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome.	got7fsn_ti							vw	2016-12-07T14:01:42Z						biological_process											owl:Class	
SO:0000624	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019580	biolink:NamedThing	galactarate metabolic process	The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose.	got7fsn_ti	mucic acid metabolic process|D-galactarate metabolic process|D-galactarate metabolism|mucic acid metabolism|galactarate metabolism										GO:0046393			biological_process											owl:Class	
GO:1900785	biolink:NamedThing	naphtho-gamma-pyrone metabolic process	The chemical reactions and pathways involving naphtho-gamma-pyrone.	got7fsn_ti	naphtho-gamma-pyrone metabolism|naphtho-gamma-pyrones metabolism|naphtho-gamma-pyrones metabolic process						di	2012-06-04T09:35:32Z						biological_process											owl:Class	
GO:0032056	biolink:NamedThing	positive regulation of translation in response to stress	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress.	got7fsn_ti	up regulation of translation in response to stress|upregulation of translation in response to stress|stimulation of translation in response to stress|activation of translation in response to stress|up-regulation of translation in response to stress													biological_process											owl:Class	
GO:1905093	biolink:NamedThing	cellular response to diosgenin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.	got7fsn_ti							bc	2016-03-31T11:04:38Z						biological_process											owl:Class	
GO:2001178	biolink:NamedThing	positive regulation of mediator complex assembly	Any process that activates or increases the frequency, rate or extent of mediator complex assembly.	got7fsn_ti							yaf	2011-11-02T11:22:27Z						biological_process											owl:Class	
GO:1902701	biolink:NamedThing	pentose catabolic process to propan-2-ol	The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol.	got7fsn_ti	pentose breakdown to propan-2-ol|pentose catabolism to propan-2-ol|solventogenesis|pentose catabolic process to isopropyl alcohol|pentose catabolic process to isopropanol|pentose degradation to propan-2-ol						tb	2014-02-19T18:28:57Z			GO:1990291			biological_process											owl:Class	
GO:0045224	biolink:NamedThing	positive regulation of CD4 production	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.	got7fsn_ti	stimulation of CD4 biosynthetic process|up-regulation of CD4 biosynthetic process|positive regulation of CD4 biosynthetic process|positive regulation of CD4 formation|positive regulation of CD4 biosynthesis|upregulation of CD4 biosynthetic process|activation of CD4 biosynthetic process|positive regulation of CD4 synthesis|up regulation of CD4 biosynthetic process|positive regulation of CD4 anabolism													biological_process											owl:Class	
GO:0050466	biolink:NamedThing	obsolete oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is not disulfide or oxygen.	got7fsn_ti	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0046992				True				molecular_function											owl:Class	
CHEBI:49747	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900010	biolink:NamedThing	regulation of corticotropin-releasing hormone receptor activity	Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity.	got7fsn_ti	regulation of corticotropin-releasing factor receptor activity|regulation of CRF receptor activity|regulation of adrenocorticotropin-releasing hormone receptor activity|regulation of CRH receptor activity						pr	2012-01-10T02:27:23Z						biological_process											owl:Class	
GO:1905897	biolink:NamedThing	regulation of response to endoplasmic reticulum stress	Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress.	got7fsn_ti	regulation of cellular response to endoplasmic reticulum stress|regulation of response to ER stress|regulation of ER stress response						bc	2017-02-01T11:42:55Z						biological_process											owl:Class	
GO:0000099	biolink:NamedThing	sulfur amino acid transmembrane transporter activity	Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.	got7fsn_ti	sulfur amino acid transporter activity|sulphur amino acid transmembrane transporter activity|sulphur amino acid transporter activity													molecular_function											owl:Class	
GO:0001884	biolink:NamedThing	pyrimidine nucleoside binding	Binding to a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose.	got7fsn_ti														molecular_function											owl:Class	
GO:0106197	biolink:NamedThing	obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a diphosphate	OBSOLETE. Catalysis of the translocation of inorganic anions llinked to the hydrolysis of a diphosphate.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:17:37Z		True		EC:7.3.3.-		molecular_function											owl:Class	
GO:1905891	biolink:NamedThing	regulation of cellular response to thapsigargin	Any process that modulates the frequency, rate or extent of cellular response to thapsigargin.	got7fsn_ti							bc	2017-02-01T11:36:07Z						biological_process											owl:Class	
GO:1904936	biolink:NamedThing	interneuron migration	The orderly movement of an interneuron from one site to another.	got7fsn_ti	inter neuron migration|inter-neuron migration						ah	2016-02-01T14:04:32Z						biological_process											owl:Class	
GO:0032904	biolink:NamedThing	negative regulation of nerve growth factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).	got7fsn_ti	negative regulation of NGF production|down-regulation of nerve growth factor production|inhibition of nerve growth factor production|downregulation of nerve growth factor production|down regulation of nerve growth factor production													biological_process											owl:Class	
GO:0043059	biolink:NamedThing	regulation of forward locomotion	Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0006100	biolink:NamedThing	obsolete tricarboxylic acid cycle intermediate metabolic process	OBSOLETE. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle.	got7fsn_ti	tricarboxylic acid cycle intermediate metabolism|Krebs cycle intermediate metabolism|TCA intermediate metabolic process|citric acid cycle intermediate metabolism|TCA intermediate metabolism|Krebs cycle intermediate metabolic process|tricarboxylic acid cycle intermediate metabolic process|citric acid cycle intermediate metabolic process				This term was made obsolete because it is a grouping term that is not useful, but has caused true path violations.	GO:0006106|GO:0006104|GO:0006108|GO:0006099|GO:0006103|GO:0006105|GO:0006101|GO:0006107				True				biological_process											owl:Class	
GO:0002853	biolink:NamedThing	negative regulation of T cell mediated cytotoxicity directed against tumor cell target	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.	got7fsn_ti	inhibition of T cell mediated cytotoxicity directed against tumor cell target|down regulation of T cell mediated cytotoxicity directed against tumor cell target|downregulation of T cell mediated cytotoxicity directed against tumor cell target|down-regulation of T cell mediated cytotoxicity directed against tumor cell target													biological_process											owl:Class	
GO:2000951	biolink:NamedThing	regulation of xyloglucan catabolic process	Any process that modulates the frequency, rate or extent of xyloglucan catabolic process.	got7fsn_ti	regulation of xyloglucan catabolism						tt	2011-08-01T02:20:16Z						biological_process											owl:Class	
GO:0051966	biolink:NamedThing	regulation of synaptic transmission, glutamatergic	Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.	got7fsn_ti														biological_process											owl:Class	
GO:0001724	biolink:NamedThing	obsolete type III intermediate filament associated protein	OBSOLETE. Proteins that associate with the ends of intermediate filaments and couple the intermediate filaments to the plasma membrane.	got7fsn_ti	type III intermediate filament associated protein			GO:0045098	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:1902341	biolink:NamedThing	xylitol transport	The directed movement of a xylitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose.	got7fsn_ti							se	2013-07-30T16:04:38Z						biological_process											owl:Class	
GO:0008492	biolink:NamedThing	obsolete cAMP generating peptide activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cAMP generating peptide activity|cyclic AMP generating peptide activity				This term was made obsolete because it describes a gene product.	GO:0004016|GO:0046058|GO:0005179				True				molecular_function											owl:Class	
GO:0052197	biolink:NamedThing	obsolete positive regulation by host of symbiont defense response	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	stimulation by host of symbiont defense response|up-regulation by host of symbiont defense response|up regulation by host of symbiont defense response|upregulation by host of symbiont defense response|activation by host of symbiont defense response				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response.					True				biological_process											owl:Class	
GO:0097637	biolink:NamedThing	integral component of autophagosome membrane	The component of the autophagosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	autophagic vacuole integral membrane protein|integral to autophagic vacuole membrane|integral component of autophagic vacuole membrane													cellular_component											owl:Class	
GO:0051166	biolink:NamedThing	2,5-dihydroxypyridine catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.	got7fsn_ti	2,5-dihydroxypyridine degradation|2,5-dihydroxypyridine catabolism|pyridine-2,5-diol catabolic process|2,5-dihydroxypyridine breakdown													biological_process											owl:Class	
GO:2001046	biolink:NamedThing	positive regulation of integrin-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.	got7fsn_ti	positive regulation of integrin-mediated signalling pathway						bf	2011-08-31T03:49:19Z						biological_process											owl:Class	
GO:1990559	biolink:NamedThing	mitochondrial coenzyme A transmembrane transport	The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:58:26Z						biological_process											owl:Class	
GO:1900946	biolink:NamedThing	positive regulation of isoprene metabolic process	Any process that activates or increases the frequency, rate or extent of isoprene metabolic process.	got7fsn_ti	up regulation of 2-methyl-1,3-butadiene metabolism|upregulation of hemiterpene metabolism|upregulation of hemiterpene metabolic process|positive regulation of hemiterpene metabolism|up-regulation of 2-methyl-1,3-butadiene metabolic process|up-regulation of hemiterpene metabolic process|up-regulation of 2-methyl-1,3-butadiene metabolism|activation of hemiterpene metabolic process|up-regulation of isoprene metabolism|upregulation of isoprene metabolism|up regulation of hemiterpene metabolic process|up regulation of 2-methyl-1,3-butadiene metabolic process|activation of 2-methyl-1,3-butadiene metabolic process|upregulation of isoprene metabolic process|up-regulation of hemiterpene metabolism|positive regulation of 2-methyl-1,3-butadiene metabolic process|positive regulation of isoprene metabolism|up regulation of hemiterpene metabolism|activation of isoprene metabolism|up-regulation of isoprene metabolic process|positive regulation of hemiterpene metabolic process|upregulation of 2-methyl-1,3-butadiene metabolic process|activation of hemiterpene metabolism|upregulation of 2-methyl-1,3-butadiene metabolism|up regulation of isoprene metabolic process|up regulation of isoprene metabolism|activation of isoprene metabolic process|activation of 2-methyl-1,3-butadiene metabolism|positive regulation of 2-methyl-1,3-butadiene metabolism						tt	2012-06-14T03:19:41Z						biological_process											owl:Class	
GO:0002838	biolink:NamedThing	negative regulation of immune response to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.	got7fsn_ti	inhibition of immune response to tumor cell|down-regulation of immune response to tumor cell|down regulation of immune response to tumor cell|negative regulation of immune response to tumour cell|downregulation of immune response to tumor cell													biological_process											owl:Class	
GO:1902228	biolink:NamedThing	positive regulation of macrophage colony-stimulating factor signaling pathway	Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.	got7fsn_ti	up-regulation of macrophage colony-stimulating factor signaling pathway|up regulation of macrophage colony-stimulating factor signalling pathway|up-regulation of macrophage colony-stimulating factor signalling pathway|activation of macrophage colony-stimulating factor signaling pathway|positive regulation of M-CSF signaling pathway|activation of macrophage colony-stimulating factor signalling pathway|positive regulation of macrophage colony-stimulating factor signalling pathway|activation of M-CSF signaling pathway|up-regulation of M-CSF signaling pathway|upregulation of macrophage colony-stimulating factor signaling pathway|upregulation of M-CSF signaling pathway|upregulation of macrophage colony-stimulating factor signalling pathway|up regulation of M-CSF signaling pathway|up regulation of macrophage colony-stimulating factor signaling pathway						lb	2013-06-14T06:29:00Z						biological_process											owl:Class	
GO:1900441	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.	got7fsn_ti	down regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|downregulation of filamentous growth of a population of unicellular organisms in response to neutral pH|down-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|inhibition of filamentous growth of a population of unicellular organisms in response to neutral pH						di	2012-04-25T05:55:57Z						biological_process											owl:Class	
GO:0044420	biolink:NamedThing	obsolete extracellular matrix component	OBSOLETE. Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).	got7fsn_ti	extracellular matrix part				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0031012				True				cellular_component											owl:Class	
GO:0036083	biolink:NamedThing	obsolete positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		bf	2011-12-20T04:52:36Z		True				biological_process											owl:Class	
GO:0002897	biolink:NamedThing	positive regulation of central B cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.	got7fsn_ti	stimulation of central B cell tolerance induction|up regulation of central B cell tolerance induction|activation of central B cell tolerance induction|up-regulation of central B cell tolerance induction|upregulation of central B cell tolerance induction													biological_process											owl:Class	
GO:0032150	biolink:NamedThing	ubiquinone biosynthetic process from chorismate	The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.	got7fsn_ti														biological_process											owl:Class	
GO:0001811	biolink:NamedThing	negative regulation of type I hypersensitivity	Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.	got7fsn_ti	downregulation of type I hypersensitivity|down-regulation of type I hypersensitivity|inhibition of type I hypersensitivity|down regulation of type I hypersensitivity													biological_process											owl:Class	
GO:0044050	biolink:NamedThing	obsolete interaction with host via substance released by sporangium lysis	OBSOLETE. An interaction with the host organism mediated by a substance released via rupture of symbiont sporangia, structures producing and containing spores. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with host via substance released by lysis of symbiont sporangium|interaction with host via substance released by sporangia lysis				This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True				biological_process											owl:Class	
GO:0008129	biolink:NamedThing	obsolete actinidain activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'.	got7fsn_ti	actinidia anionic protease activity|actinidain activity|actinidin activity|proteinase A2 of actinidia chinensis			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
OBO:OBA_0000160	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901319	biolink:NamedThing	positive regulation of trehalose catabolic process	Any process that activates or increases the frequency, rate or extent of trehalose catabolic process.	got7fsn_ti	activation of trehalose degradation|activation of mycose catabolism|positive regulation of mycose catabolic process|upregulation of trehalose degradation|positive regulation of mykose catabolism|upregulation of trehalose breakdown|up regulation of trehalose catabolism|up-regulation of mykose catabolism|up regulation of mykose catabolism|up regulation of mykose catabolic process|up regulation of trehalose catabolic process|positive regulation of trehalose catabolism|positive regulation of mykose catabolic process|upregulation of mykose catabolism|up-regulation of trehalose catabolic process|up-regulation of mycose catabolic process|up-regulation of mykose catabolic process|upregulation of mycose catabolic process|positive regulation of trehalose degradation|up-regulation of trehalose degradation|up regulation of mycose catabolic process|positive regulation of trehalose breakdown|upregulation of mykose catabolic process|activation of mycose catabolic process|up regulation of trehalose breakdown|upregulation of trehalose catabolism|upregulation of mycose catabolism|activation of mykose catabolic process|activation of trehalose catabolic process|up regulation of mycose catabolism|activation of trehalose breakdown|up regulation of trehalose degradation|up-regulation of trehalose catabolism|activation of trehalose catabolism|activation of mykose catabolism|up-regulation of trehalose breakdown|upregulation of trehalose catabolic process|positive regulation of mycose catabolism|up-regulation of mycose catabolism						al	2012-08-24T12:57:52Z						biological_process											owl:Class	
GO:1902513	biolink:NamedThing	regulation of organelle transport along microtubule	Any process that modulates the frequency, rate or extent of organelle transport along microtubule.	got7fsn_ti	regulation of microtubule-based organelle localization						dph	2013-11-15T20:15:17Z						biological_process											owl:Class	
GO:0097283	biolink:NamedThing	keratinocyte apoptotic process	Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.	got7fsn_ti	keratinocyte apoptosis						pr	2012-03-29T10:20:51Z						biological_process											owl:Class	
GO:0075266	biolink:NamedThing	negative regulation of oogonium development	Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.	got7fsn_ti														biological_process											owl:Class	
GO:1905289	biolink:NamedThing	regulation of CAMKK-AMPK signaling cascade	Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade.	got7fsn_ti	regulation of stress-activated AMP-activated protein kinase signaling cascade						sl	2016-06-23T20:36:55Z						biological_process											owl:Class	
CHEBI:61310	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052563	biolink:NamedThing	obsolete negative regulation by organism of symbiont immune response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of symbiont immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1901810	biolink:NamedThing	beta-carotene metabolic process	The chemical reactions and pathways involving beta-carotene.	got7fsn_ti	beta-carotene metabolism						yaf	2013-01-22T10:30:23Z						biological_process											owl:Class	
GO:1905735	biolink:NamedThing	regulation of L-proline import across plasma membrane	Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane.	got7fsn_ti							vw	2016-12-04T20:42:16Z						biological_process											owl:Class	
GO:1900222	biolink:NamedThing	negative regulation of amyloid-beta clearance	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance.	got7fsn_ti	negative regulation of beta-amyloid clearance|inhibition of beta-amyloid clearance|downregulation of beta-amyloid clearance|down regulation of beta-amyloid clearance|down-regulation of beta-amyloid clearance						vk	2012-03-22T01:29:41Z						biological_process											owl:Class	
GO:1903652	biolink:NamedThing	modulation by virus of host cytoplasmic transport	Modulation by an infecting virus of host cytoplasmic transport.	got7fsn_ti	regulation by virus of host cytoplasmic streaming|viral modulation of host cytoplasmic trafficking|regulation by virus of host cytoplasmic transport						jl	2014-11-24T17:22:04Z						biological_process											owl:Class	
GO:1903628	biolink:NamedThing	negative regulation of dUTP diphosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of dUTP diphosphatase activity.	got7fsn_ti	down-regulation of dUTPase activity|downregulation of dUTP nucleotidohydrolase activity|down-regulation of dUTP nucleotidohydrolase activity|down regulation of dUTP diphosphatase activity|inhibition of dUTP nucleotidohydrolase activity|negative regulation of dUTP pyrophosphatase activity|down regulation of dUTPase activity|downregulation of dUTPase activity|inhibition of desoxyuridine 5'-triphosphatase activity|negative regulation of dUTP nucleotidohydrolase activity|down regulation of dUTP pyrophosphatase activity|down regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|inhibition of dUTPase activity|down regulation of dUTP nucleotidohydrolase activity|inhibition of deoxyuridine-triphosphatase activity|down-regulation of dUTP diphosphatase activity|negative regulation of deoxyuridine-triphosphatase activity|negative regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|downregulation of dUTP diphosphatase activity|inhibition of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|negative regulation of dUTPase activity|down-regulation of deoxyuridine-triphosphatase activity|downregulation of deoxyuridine-triphosphatase activity|down-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|negative regulation of desoxyuridine 5'-triphosphatase activity|downregulation of dUTP pyrophosphatase activity|down-regulation of desoxyuridine 5'-triphosphatase activity|down regulation of desoxyuridine 5'-triphosphatase activity|inhibition of dUTP pyrophosphatase activity|downregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|downregulation of desoxyuridine 5'-triphosphatase activity|down-regulation of dUTP pyrophosphatase activity|down regulation of deoxyuridine-triphosphatase activity|inhibition of dUTP diphosphatase activity						sl	2014-11-20T00:00:44Z						biological_process											owl:Class	
GO:0097064	biolink:NamedThing	ncRNA export from nucleus	The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm.	got7fsn_ti	non-coding RNA export from nucleus						pr	2011-06-08T12:34:34Z						biological_process											owl:Class	
GO:1900418	biolink:NamedThing	obsolete positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process.	got7fsn_ti	up-regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-20T10:13:58Z		True				biological_process											owl:Class	
GO:0006682	biolink:NamedThing	galactosylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.	got7fsn_ti	galactosylceramide synthesis|galactosylceramide biosynthesis|galactosylceramide anabolism|galactosylceramide formation													biological_process											owl:Class	
GO:0006733	biolink:NamedThing	obsolete oxidoreduction coenzyme metabolic process	OBSOLETE. The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed.	got7fsn_ti	oxidoreduction coenzyme metabolism				1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True				biological_process											owl:Class	
GO:1902971	biolink:NamedThing	mitotic DNA replication DNA duplex unwinding	Any DNA duplex unwinding involved in mitotic cell cycle DNA replication.	got7fsn_ti	DNA duplex unwinding involved in mitotic DNA replication|DNA duplex unwinding involved in mitotic cell cycle DNA replication						jl	2014-05-06T15:20:47Z						biological_process											owl:Class	
GO:0045950	biolink:NamedThing	negative regulation of mitotic recombination	Any process that inhibits or decreases the rate of DNA recombination during mitosis.	got7fsn_ti	down-regulation of mitotic recombination|down regulation of mitotic recombination|inhibition of mitotic recombination|downregulation of mitotic recombination|negative regulation of recombination within rDNA repeats													biological_process											owl:Class	
GO:1990797	biolink:NamedThing	obsolete cholecystokinin secretion	OBSOLETE. The controlled release of cholecystokinin from a cell. Cholecystokinin is a peptide hormone that participates in pancreatic enzyme release in the gut and is also found in the brain.	got7fsn_ti	CCK secretion				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-07-09T23:14:23Z		True				biological_process											owl:Class	
GO:0061423	biolink:NamedThing	positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter resulting in the increased frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							dph	2012-01-26T12:52:05Z						biological_process											owl:Class	
CHEBI:58515	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032387	biolink:NamedThing	negative regulation of intracellular transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.	got7fsn_ti	down-regulation of intracellular transport|down regulation of intracellular transport|inhibition of intracellular transport|downregulation of intracellular transport													biological_process											owl:Class	
GO:1905453	biolink:NamedThing	regulation of myeloid progenitor cell differentiation	Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation.	got7fsn_ti							rz	2016-09-16T12:32:18Z						biological_process											owl:Class	
GO:0019567	biolink:NamedThing	arabinose biosynthetic process	The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose.	got7fsn_ti	arabinose biosynthesis|arabinose anabolism|arabinose formation|arabinose synthesis													biological_process											owl:Class	
GO:0030400	biolink:NamedThing	obsolete protease substrate recruitment factor activity	OBSOLETE. A recruiting factor or adaptor molecule associated with the proteasome that activates degradation of specific proteasomal substrates and links them to the degradation machinery; it is not involved in ubiquitination; does not possess proteolytic activity.	got7fsn_ti	protease substrate recruitment factor activity				This term was made obsolete because it represents a gene product.	GO:0030674				True				molecular_function											owl:Class	
GO:0031355	biolink:NamedThing	integral component of plastid outer membrane	The component of the plastid outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to plastid outer membrane													cellular_component											owl:Class	
GO:0006862	biolink:NamedThing	nucleotide transport	The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell.	got7fsn_ti														biological_process											owl:Class	
GO:2001256	biolink:NamedThing	regulation of store-operated calcium entry	Any process that modulates the frequency, rate or extent of store-operated calcium entry.	got7fsn_ti	regulation of calcium ion import|regulation of SOCE|regulation of store-operated calcium import|regulation of capacitative calcium entry						vk	2011-12-07T07:08:38Z						biological_process											owl:Class	
GO:0070401	biolink:NamedThing	NADP+ binding	Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.	got7fsn_ti	oxidized nicotinamide adenine dinucleotide phosphate binding|NADP binding|NADP (oxidized) binding|oxidized NADP binding													molecular_function											owl:Class	
GO:0002887	biolink:NamedThing	negative regulation of myeloid leukocyte mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.	got7fsn_ti	down regulation of myeloid leukocyte mediated immunity|inhibition of myeloid leukocyte mediated immunity|down-regulation of myeloid leukocyte mediated immunity|downregulation of myeloid leukocyte mediated immunity													biological_process											owl:Class	
GO:0001308	biolink:NamedThing	obsolete negative regulation of chromatin silencing involved in replicative cell aging	OBSOLETE. The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins.	got7fsn_ti	loss of chromatin silencing during replicative cell ageing|loss of chromatin silencing involved in replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:1903315	biolink:NamedThing	negative regulation of nitrogen cycle metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process.	got7fsn_ti	down-regulation of nitrogen cycle metabolic process|downregulation of nitrogen cycle metabolic process|down regulation of nitrogen cycle metabolic process|inhibition of nitrogen cycle metabolic process						vw	2014-08-18T12:57:42Z						biological_process											owl:Class	
GO:0019675	biolink:NamedThing	obsolete NAD phosphorylation and dephosphorylation	OBSOLETE. The addition or removal of a phosphate group from nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.	got7fsn_ti	nicotinamide adenine dinucleotide phosphorylation and dephosphorylation|NAD phosphorylation and dephosphorylation				This term was made obsolete because it represents a process, NAD dephosphorylation, that does not exist.	GO:0019674|GO:0006739				True				biological_process											owl:Class	
GO:0005240	biolink:NamedThing	obsolete glycine receptor-associated protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	glycine receptor-associated protein				This term was made obsolete because it does not describe a molecular function.	GO:0005515				True				molecular_function											owl:Class	
GO:1900983	biolink:NamedThing	vindoline metabolic process	The chemical reactions and pathways involving vindoline.	got7fsn_ti	vindoline metabolism						yaf	2012-06-14T09:16:29Z						biological_process											owl:Class	
GO:1900444	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.	got7fsn_ti	inhibition of filamentous growth of a population of unicellular organisms in response to biotic stimulus|downregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|down-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|down regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus						di	2012-04-25T05:56:27Z						biological_process											owl:Class	
GO:0030711	biolink:NamedThing	positive regulation of border follicle cell delamination	Any process that increases the frequency, rate or extent of border cell delamination.	got7fsn_ti	stimulation of border follicle cell delamination|positive regulation of border cell delamination|upregulation of border follicle cell delamination|up regulation of border follicle cell delamination|up-regulation of border follicle cell delamination|activation of border follicle cell delamination													biological_process											owl:Class	
GO:1902876	biolink:NamedThing	negative regulation of embryonic pattern specification	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification.	got7fsn_ti	down-regulation of ventral/lateral system|downregulation of embryonic pattern specification|down regulation of embryonic pattern specification|inhibition of ventral/lateral system|inhibition of embryonic pattern specification|down-regulation of embryonic pattern specification|negative regulation of ventral/lateral system|down regulation of ventral/lateral system|downregulation of ventral/lateral system						mr	2014-04-03T15:25:20Z						biological_process											owl:Class	
GO:0045660	biolink:NamedThing	positive regulation of neutrophil differentiation	Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.	got7fsn_ti	up regulation of neutrophil differentiation|stimulation of neutrophil differentiation|upregulation of neutrophil differentiation|activation of neutrophil differentiation|up-regulation of neutrophil differentiation													biological_process											owl:Class	
GO:0019322	biolink:NamedThing	pentose biosynthetic process	The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.	got7fsn_ti	pentose biosynthesis|pentose anabolism|pentose synthesis|pentose formation													biological_process											owl:Class	
GO:0009148	biolink:NamedThing	pyrimidine nucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside triphosphate anabolism|pyrimidine nucleoside triphosphate synthesis|pyrimidine nucleoside triphosphate formation|pyrimidine nucleoside triphosphate biosynthesis													biological_process											owl:Class	
GO:1905547	biolink:NamedThing	obsolete regulation of subtelomeric heterochromatin assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of subtelomeric heterochromatin assembly.	got7fsn_ti	regulation of telomeric heterochromatin formation|regulation of telomeric heterochromatin assembly	https://github.com/geneontology/go-ontology/issues/22027|https://github.com/geneontology/go-ontology/issues/19188			This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.		nc	2016-10-12T11:14:00Z		True				biological_process											owl:Class	
GO:0018966	biolink:NamedThing	styrene metabolic process	The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen.	got7fsn_ti	styrene metabolism											UM-BBD_pathwayID:sty		biological_process											owl:Class	
GO:0046206	biolink:NamedThing	trypanothione metabolic process	The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.	got7fsn_ti	trypanothione metabolism													biological_process											owl:Class	
GO:0002894	biolink:NamedThing	positive regulation of type II hypersensitivity	Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.	got7fsn_ti	up-regulation of type II hypersensitivity|stimulation of type II hypersensitivity|up regulation of type II hypersensitivity|activation of type II hypersensitivity|upregulation of type II hypersensitivity													biological_process											owl:Class	
GO:1903866	biolink:NamedThing	palisade mesophyll development	The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure.	got7fsn_ti	palisade parenchyma development						tb	2015-02-04T21:51:44Z						biological_process											owl:Class	
GO:1902952	biolink:NamedThing	positive regulation of dendritic spine maintenance	Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.	got7fsn_ti	upregulation of dendritic spine maintenance|activation of dendritic spine maintenance|up-regulation of dendritic spine maintenance|up regulation of dendritic spine maintenance						sjp	2014-05-02T08:48:59Z						biological_process											owl:Class	
GO:0042801	biolink:NamedThing	obsolete polo kinase kinase activity	OBSOLETE. Catalysis of the addition of a phosphate group onto a serine or threonine residue in any member of the polo kinase class of proteins.	got7fsn_ti					This term was made obsolete because it represents a gene product and also refers to a non-existent activity (polo kinase).					True				molecular_function											owl:Class	
GO:0006339	biolink:NamedThing	obsolete positive regulation of transcription of homeotic gene (trithorax group)	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the trithorax group.	got7fsn_ti	positive regulation of transcription of homeotic gene (trithorax group)				This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0031507|GO:0048096|GO:0045944				True				biological_process											owl:Class	
GO:0072388	biolink:NamedThing	flavin adenine dinucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.	got7fsn_ti	flavin adenine dinucleotide anabolism|FAD or FADH2 biosynthetic process|flavin adenine dinucleotide biosynthesis|flavin adenine dinucleotide synthesis|flavin adenine dinucleotide formation						mah	2010-12-02T04:26:34Z						biological_process											owl:Class	
GO:0043030	biolink:NamedThing	regulation of macrophage activation	Any process that modulates the frequency or rate of macrophage activation.	got7fsn_ti	regulation of macrophage polarization													biological_process											owl:Class	
GO:0090366	biolink:NamedThing	positive regulation of mRNA modification	Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti							tb	2010-07-12T11:04:45Z						biological_process											owl:Class	
GO:1902421	biolink:NamedThing	hydrogen metabolic process	The chemical reactions and pathways involving H2 (dihydrogen).	got7fsn_ti	H2 metabolism|dihydrogen metabolism|molecular hydrogen metabolism						jl	2013-09-18T14:34:23Z						biological_process											owl:Class	
GO:0099149	biolink:NamedThing	regulation of postsynaptic neurotransmitter receptor internalization	Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse.	got7fsn_ti	regulation of postsynaptic neurotransmitter receptor endocytosis						dos	2017-07-05T13:13:49Z						biological_process											owl:Class	
GO:0150143	biolink:NamedThing	regulation of CD80 production	Any process that modulates the frequency, rate or extent of CD80 biosynthetic process.	got7fsn_ti	regulation of CD80 biosynthetic process						bc	2019-12-08T10:23:43Z						biological_process											owl:Class	
GO:0050783	biolink:NamedThing	cocaine metabolic process	The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.	got7fsn_ti	cocaine metabolism													biological_process											owl:Class	
GO:0006778	biolink:NamedThing	porphyrin-containing compound metabolic process	The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.	got7fsn_ti	porphyrin metabolic process|porphyrin metabolism													biological_process											owl:Class	
GO:0003784	biolink:NamedThing	obsolete barbed-end actin capping/severing activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	barbed-end actin capping/severing activity				This term was made obsolete because it describes two biological processes.	GO:0051016|GO:0051014				True				molecular_function											owl:Class	
GO:1903769	biolink:NamedThing	negative regulation of cell proliferation in bone marrow	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow.	got7fsn_ti	down-regulation of cell proliferation in bone marrow|down-regulation of bone marrow cell proliferation|downregulation of bone marrow cell proliferation|down regulation of bone marrow cell proliferation|inhibition of bone marrow cell proliferation|inhibition of cell proliferation in bone marrow|downregulation of cell proliferation in bone marrow|down regulation of cell proliferation in bone marrow|negative regulation of bone marrow cell proliferation						sl	2014-12-29T19:46:26Z						biological_process											owl:Class	
GO:0016700	biolink:NamedThing	obsolete oxidoreductase activity, acting on hydrogen as donor, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen is the electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP or a quinone or similar compound.	got7fsn_ti	oxidoreductase activity, acting on hydrogen as donor, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016695				True				molecular_function											owl:Class	
GO:0023040	biolink:NamedThing	obsolete signaling via ionic flux	OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via ionic flux.	got7fsn_ti	signaling via ionic flux|signalling via ionic flux				This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:2000785	biolink:NamedThing	regulation of autophagosome assembly	Any process that modulates the frequency, rate or extent of autophagosome assembly.	got7fsn_ti	regulation of autophagosome formation|regulation of autophagic vacuole formation|regulation of PAS formation|regulation of autophagic vacuole assembly|regulation of autophagosome biosynthesis						rl	2011-06-24T11:19:08Z						biological_process											owl:Class	
GO:0010517	biolink:NamedThing	regulation of phospholipase activity	Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.	got7fsn_ti														biological_process											owl:Class	
GO:0006496	biolink:NamedThing	obsolete protein amino acid terminal N-glycosylation	OBSOLETE. The glycosylation of a nitrogen atom of a free alpha amino terminal of a peptide.	got7fsn_ti	protein amino acid terminal N-glycosylation				This term was made obsolete because the term name is ambiguous.	GO:0006487|GO:0035629				True				biological_process											owl:Class	
GO:0045348	biolink:NamedThing	positive regulation of MHC class II biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.	got7fsn_ti	up-regulation of MHC class II biosynthetic process|positive regulation of MHC class II synthesis|positive regulation of MHC class II anabolism|positive regulation of major histocompatibility complex class II biosynthesis|stimulation of MHC class II biosynthetic process|positive regulation of major histocompatibility complex class II biosynthetic process|positive regulation of MHC class II formation|upregulation of MHC class II biosynthetic process|up regulation of MHC class II biosynthetic process|positive regulation of MHC class II biosynthesis|activation of MHC class II biosynthetic process													biological_process											owl:Class	
GO:2000187	biolink:NamedThing	positive regulation of phosphate transmembrane transport	Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport.	got7fsn_ti	positive regulation of phosphate membrane transport						vw	2010-10-15T11:33:10Z						biological_process											owl:Class	
GO:0072363	biolink:NamedThing	obsolete regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of glycolysis by positive regulation of transcription from an RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:08:25Z		True				biological_process											owl:Class	
GO:1902459	biolink:NamedThing	positive regulation of stem cell population maintenance	Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.	got7fsn_ti	positive regulation of maintenance of pluripotency|upregulation of maintenance of pluripotency|up-regulation of stem cell maintenance|up regulation of maintenance of pluripotency|up-regulation of maintenance of pluripotency|activation of maintenance of pluripotency|upregulation of stem cell maintenance|up regulation of stem cell maintenance|activation of stem cell maintenance						cjm	2013-10-16T22:27:47Z						biological_process											owl:Class	
GO:1904425	biolink:NamedThing	negative regulation of GTP binding	Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding.	got7fsn_ti	down-regulation of GTP binding|down regulation of GTP binding|inhibition of GTP binding|downregulation of GTP binding						sl	2015-07-02T20:35:01Z						biological_process											owl:Class	
GO:0045977	biolink:NamedThing	positive regulation of mitotic cell cycle, embryonic	Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle.	got7fsn_ti	positive regulation of embryonic mitotic cell cycle progression|stimulation of mitotic cell cycle, embryonic|up-regulation of mitotic cell cycle, embryonic|activation of mitotic cell cycle, embryonic|upregulation of mitotic cell cycle, embryonic|positive regulation of embryonic mitotic cell cycle|up regulation of mitotic cell cycle, embryonic|positive regulation of progression through embryonic mitotic cell cycle													biological_process											owl:Class	
GO:0016594	biolink:NamedThing	glycine binding	Binding to glycine, aminoethanoic acid.	got7fsn_ti	Gly binding|aminoacetic acid binding|aminoethanoic acid binding													molecular_function											owl:Class	
GO:0007150	biolink:NamedThing	obsolete growth pattern	OBSOLETE. A process whereby cells develop a specific morphology under a specific set of circumstances.	got7fsn_ti	growth pattern				This term was made obsolete because the original meaning of the term is unclear, the current definition is incorrect, and it does not describe a biological process.	GO:0040007				True				biological_process											owl:Class	
GO:1902485	biolink:NamedThing	L-cysteine binding	Binding to L-cysteine.	got7fsn_ti							bhm	2013-11-12T09:06:28Z						molecular_function											owl:Class	
GO:0039567	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by retaining STAT1 in the cytoplasm, so STAT1 is unable to translocate to the nucleus to activate transcription of its target genes.	got7fsn_ti	suppression by virus of host STAT1 activity by cytoplasmic sequestering of STAT1|cytoplasmic sequestration of STAT1				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:24:36Z		True				biological_process											owl:Class	
GO:2000476	biolink:NamedThing	positive regulation of opioid receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway.	got7fsn_ti	positive regulation of opioid receptor signalling pathway						bf	2011-03-09T09:41:35Z						biological_process											owl:Class	
GO:0045589	biolink:NamedThing	regulation of regulatory T cell differentiation	Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells.	got7fsn_ti	regulation of suppressor T lymphocyte differentiation|regulation of regulatory T cell development|regulation of regulatory T-cell differentiation|regulation of regulatory T lymphocyte differentiation|regulation of suppressor T-lymphocyte differentiation|regulation of suppressor T-cell differentiation|regulation of regulatory T-lymphocyte differentiation|regulation of suppressor T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1990967	biolink:NamedThing	obsolete multi-organism toxin transport	OBSOLETE. The directed movement of a toxin into, out of or within a cell, or between cells where two or more organisms of the same or different species are involved.	got7fsn_ti	typhoid toxin transport				This term was obsoleted because there is no evidence that this process exists.		bf	2016-06-21T09:01:39Z		True				biological_process											owl:Class	
GO:1904700	biolink:NamedThing	granulosa cell apoptotic process	Any apoptotic process in a granulosa cell.	got7fsn_ti	granulosa cell of ovary apoptosis|granulosa cell apoptosis|granulosa cell of ovary apoptotic process						sl	2015-09-30T21:29:54Z						biological_process											owl:Class	
GO:0006676	biolink:NamedThing	mannosyl diphosphorylinositol ceramide metabolic process	The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative.	got7fsn_ti	M(IP)2C metabolic process|M(IP)2C metabolism|mannosyl diphosphorylinositol ceramide metabolism													biological_process											owl:Class	
GO:1990755	biolink:NamedThing	mitotic spindle microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle.	got7fsn_ti	mitotic spindle microtubule depolymerisation						mah	2015-05-28T15:42:06Z						biological_process											owl:Class	
GO:1903408	biolink:NamedThing	positive regulation of P-type sodium:potassium-exchanging transporter activity	Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.	got7fsn_ti	positive regulation of Na(+)/K(+)-ATPase activity|positive regulation of sodium/potassium-exchanging ATPase activity|activation of Na+/K+-exchanging ATPase activity|positive regulation of ATP phosphohydrolase (Na+/K+-exchanging)|upregulation of Na+/K+-ATPase activity|up regulation of (Na+ + K+)-ATPase activity|up regulation of (Na+ + K+)-activated ATPase activity|activation of sodium/potassium-exchanging ATPase activity|upregulation of sodium/potassium-exchanging ATPase activity|positive regulation of Na,K-pump|up regulation of Na(+)/K(+)-exchanging ATPase activity|up regulation of ATP phosphohydrolase (Na+/K+-exchanging)|upregulation of sodium:potassium exchanging ATPase activity|up-regulation of sodium:potassium exchanging ATPase activity|up regulation of Na+/K+-exchanging ATPase activity|upregulation of (Na+ + K+)-ATPase activity|up-regulation of (Na+ + K+)-ATPase activity|activation of sodium/potassium-transporting ATPase activity|up regulation of Na+/K+-ATPase activity|positive regulation of Na+/K+-ATPase activity|positive regulation of sodium:potassium-exchanging ATPase activity|upregulation of Na+,K+-ATPase activity|upregulation of Na+/K+-exchanging ATPase activity|activation of Na,K-activated ATPase activity|positive regulation of Na+/K+-exchanging ATPase activity|activation of Na(+)/K(+)-ATPase activity|up-regulation of Na+/K+-exchanging ATPase activity|up-regulation of Na+,K+ pump|up-regulation of Na+,K+-ATPase activity|up-regulation of Na(+)/K(+)-exchanging ATPase activity|upregulation of sodium:potassium-exchanging ATPase activity|upregulation of Na+,K+ pump|up-regulation of ATP phosphohydrolase (Na+/K+-exchanging)|up regulation of Na,K-activated ATPase activity|activation of (Na+ + K+)-activated ATPase activity|upregulation of Na,K-pump|up-regulation of Na,K-activated ATPase activity|upregulation of sodium/potassium-transporting ATPase activity|upregulation of Na,K-activated ATPase activity|up regulation of sodium/potassium-exchanging ATPase activity|positive regulation of Na+,K+-ATPase activity|activation of Na(+)/K(+)-exchanging ATPase activity|up regulation of Na,K-pump|upregulation of (Na+ + K+)-activated ATPase activity|up-regulation of (Na+ + K+)-activated ATPase activity|up-regulation of sodium/potassium-transporting ATPase activity|positive regulation of Na+,K+ pump|activation of sodium:potassium exchanging ATPase activity|activation of (Na+ + K+)-ATPase activity|up regulation of Na+,K+ pump|positive regulation of sodium:potassium exchanging ATPase activity|positive regulation of Na(+)/K(+)-exchanging ATPase activity|positive regulation of Na,K-activated ATPase activity|positive regulation of sodium/potassium-transporting ATPase activity|up-regulation of Na(+)/K(+)-ATPase activity|activation of ATP phosphohydrolase (Na+/K+-exchanging)|up-regulation of Na,K-pump|positive regulation of (Na+ + K+)-ATPase activity|activation of sodium:potassium-exchanging ATPase activity|up-regulation of sodium:potassium-exchanging ATPase activity|up regulation of sodium/potassium-transporting ATPase activity|activation of Na+/K+-ATPase activity|activation of Na,K-pump|up-regulation of sodium/potassium-exchanging ATPase activity|upregulation of ATP phosphohydrolase (Na+/K+-exchanging)|up-regulation of Na+/K+-ATPase activity|up regulation of sodium:potassium-exchanging ATPase activity|up regulation of Na(+)/K(+)-ATPase activity|activation of Na+,K+ pump|up regulation of Na+,K+-ATPase activity|upregulation of Na(+)/K(+)-ATPase activity|up regulation of sodium:potassium exchanging ATPase activity|positive regulation of (Na+ + K+)-activated ATPase activity|upregulation of Na(+)/K(+)-exchanging ATPase activity|activation of Na+,K+-ATPase activity						mr	2014-09-02T19:45:24Z						biological_process											owl:Class	
GO:0030304	biolink:NamedThing	obsolete trypsin inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase trypsin.	got7fsn_ti	trypsin inhibitor activity			GO:0004867	This term was made obsolete because it represents a regulator of an obsolete molecular function.					True				molecular_function											owl:Class	
GO:1902297	biolink:NamedThing	cell cycle DNA replication DNA unwinding	Any DNA unwinding that is involved in cell cycle DNA replication.	got7fsn_ti	DNA unwinding factor involved in cell cycle DNA replication|DNA unwinding during replication involved in cell cycle DNA replication|DNA unwinding involved in cell cycle DNA replication						jl	2013-07-10T11:47:10Z						biological_process											owl:Class	
GO:0034160	biolink:NamedThing	negative regulation of toll-like receptor 8 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 8 signalling pathway|negative regulation of TLR8 signaling pathway													biological_process											owl:Class	
GO:1903045	biolink:NamedThing	neural crest cell migration involved in sympathetic nervous system development	Any neural crest cell migration that is involved in sympathetic nervous system development.	got7fsn_ti					Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development		rl	2014-05-22T07:06:02Z						biological_process											owl:Class	
PR:000011387	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900695	biolink:NamedThing	regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.	got7fsn_ti	regulation of N',N'',N'''-triacetylfusarinine C formation|regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|regulation of N',N'',N'''-triacetylfusarinine C anabolism|regulation of N',N'',N'''-triacetylfusarinine C synthesis						di	2012-05-22T04:54:24Z						biological_process											owl:Class	
GO:1901495	biolink:NamedThing	negative regulation of cysteine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process.	got7fsn_ti	down regulation of cysteine metabolism|inhibition of cysteine metabolism|inhibition of cysteine metabolic process|down-regulation of cysteine metabolic process|negative regulation of cysteine metabolism|down regulation of cysteine metabolic process|downregulation of cysteine metabolism|down-regulation of cysteine metabolism|downregulation of cysteine metabolic process						vw	2012-10-16T14:28:47Z						biological_process											owl:Class	
GO:0086038	biolink:NamedThing	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell.	got7fsn_ti							tb	2011-11-11T03:33:44Z						molecular_function											owl:Class	
GO:0007579	biolink:NamedThing	obsolete senescence factor accumulation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	senescence factor accumulation				This term was made obsolete because it does not represent a process.					True				biological_process											owl:Class	
GO:0140654	biolink:NamedThing	tryprostatin A biosynthetic process	The chemical reactions and pathways resulting in the formation of tryprostatin A.	got7fsn_ti	tryprostatin A synthesis|tryprostatin A anabolism|tryprostatin A biosynthesis|tryprostatin A formation	https://github.com/geneontology/go-ontology/issues/21495					pg	2021-05-27T08:39:56Z						biological_process											owl:Class	
GO:1904760	biolink:NamedThing	regulation of myofibroblast differentiation	Any process that modulates the frequency, rate or extent of myofibroblast differentiation.	got7fsn_ti	regulation of myofibroblast cell differentiation						rph	2015-10-23T12:15:05Z						biological_process											owl:Class	
GO:1903444	biolink:NamedThing	negative regulation of brown fat cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.	got7fsn_ti	down-regulation of brown adipocyte cell differentiation|inhibition of brown adipocyte differentiation|negative regulation of brown adipocyte differentiation|down regulation of brown adipocyte differentiation|negative regulation of brown adipocyte cell differentiation|down regulation of brown adipocyte cell differentiation|down regulation of brown fat cell differentiation|downregulation of brown adipocyte differentiation|downregulation of brown fat cell differentiation|downregulation of brown adipocyte cell differentiation|inhibition of brown adipocyte cell differentiation|down-regulation of brown adipocyte differentiation|inhibition of brown fat cell differentiation|down-regulation of brown fat cell differentiation						hjd	2014-09-17T19:15:00Z						biological_process											owl:Class	
GO:0010695	biolink:NamedThing	regulation of mitotic spindle pole body separation	Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.	got7fsn_ti	regulation of SPB separation													biological_process											owl:Class	
UBERON:0002872	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902894	biolink:NamedThing	negative regulation of pri-miRNA transcription by RNA polymerase II	Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.	got7fsn_ti	down-regulation of pri-miRNA transcription from RNA polymerase II promoter|inhibition of pri-miRNA transcription from RNA polymerase II promoter|down regulation of pri-miRNA transcription from RNA polymerase II promoter|negative regulation of pri-miRNA transcription from RNA polymerase II promoter|downregulation of pri-miRNA transcription from RNA polymerase II promoter						dph	2014-04-08T13:22:14Z						biological_process											owl:Class	
GO:0038012	biolink:NamedThing	negative regulation of Wnt signaling pathway by Wnt receptor internalization	Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction.	got7fsn_ti	negative regulation of Wnt receptor signalling pathway by Wnt receptor internalization|negative regulation of Wnt receptor signaling pathway by Wnt receptor endocytosis|ligand-dependent internalization of Frizzled|negative regulation of Wnt-activated signaling pathway by Wnt receptor internalization|negative regulation of Wnt receptor signaling pathway by Wnt receptor internalization						bf	2011-06-23T03:57:59Z						biological_process											owl:Class	
GO:0016110	biolink:NamedThing	tetraterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.	got7fsn_ti	tetraterpenoid degradation|tetraterpene catabolic process|tetraterpenoid breakdown|tetraterpenoid catabolism|tetraterpene catabolism													biological_process											owl:Class	
GO:0090334	biolink:NamedThing	regulation of cell wall (1->3)-beta-D-glucan biosynthetic process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.	got7fsn_ti	regulation of cell wall 1,3-beta-D-glucan biosynthetic process|regulation of cell wall 1,3-beta-glucan biosynthetic process						tb	2010-06-01T03:11:34Z						biological_process											owl:Class	
GO:1904980	biolink:NamedThing	positive regulation of endosome organization	Any process that activates or increases the frequency, rate or extent of endosome organization.	got7fsn_ti	upregulation of endosome organisation|activation of endosome organisation|up-regulation of endosome organization and biogenesis|up-regulation of endosome organisation|up-regulation of endosome organization|positive regulation of endosome organisation|positive regulation of endosome organization and biogenesis|activation of endosome organization|up regulation of endosome organization and biogenesis|activation of endosome organization and biogenesis|upregulation of endosome organization and biogenesis|up regulation of endosome organization|up regulation of endosome organisation|upregulation of endosome organization						pad	2016-02-22T19:21:16Z						biological_process											owl:Class	
GO:0071899	biolink:NamedThing	obsolete negative regulation of estrogen receptor binding	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19354			This term was obsoleted because it represents a molecular function.		mah	2010-09-15T02:51:10Z		True				biological_process											owl:Class	
GO:0018324	biolink:NamedThing	obsolete enzyme active site formation via L-cysteine sulfenic acid	OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase.	got7fsn_ti	enzyme active site formation via L-cysteine sulphenic acid	https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:10964927 and PMID:9587003.					True		RESID:AA0205		biological_process											owl:Class	
GO:0044134	biolink:NamedThing	obsolete development of symbiont on or near host phyllosphere	OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-04T04:10:58Z		True				biological_process											owl:Class	
GO:1901081	biolink:NamedThing	negative regulation of relaxation of smooth muscle	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle.	got7fsn_ti	inhibition of smooth muscle relaxation|inhibition of relaxation of smooth muscle|down-regulation of smooth muscle relaxation|negative regulation of smooth muscle relaxation|down regulation of smooth muscle relaxation|downregulation of smooth muscle relaxation|down-regulation of relaxation of smooth muscle|down regulation of relaxation of smooth muscle|downregulation of relaxation of smooth muscle						jl	2012-07-04T10:45:31Z						biological_process											owl:Class	
GO:1901352	biolink:NamedThing	negative regulation of phosphatidylglycerol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process.	got7fsn_ti	downregulation of phosphatidylglycerol biosynthetic process|inhibition of phosphatidylglycerol formation|down-regulation of phosphatidylglycerol synthesis|down regulation of phosphatidylglycerol synthesis|down-regulation of phosphatidylglycerol biosynthetic process|down-regulation of phosphatidylglycerol formation|inhibition of phosphatidylglycerol synthesis|down-regulation of phosphatidylglycerol anabolism|down regulation of phosphatidylglycerol biosynthesis|downregulation of phosphatidylglycerol synthesis|negative regulation of phosphatidylglycerol biosynthesis|inhibition of phosphatidylglycerol biosynthetic process|inhibition of phosphatidylglycerol anabolism|down-regulation of phosphatidylglycerol biosynthesis|inhibition of phosphatidylglycerol biosynthesis|downregulation of phosphatidylglycerol anabolism|downregulation of phosphatidylglycerol biosynthesis|negative regulation of phosphatidylglycerol formation|down regulation of phosphatidylglycerol biosynthetic process|negative regulation of phosphatidylglycerol synthesis|down regulation of phosphatidylglycerol formation|downregulation of phosphatidylglycerol formation|negative regulation of phosphatidylglycerol anabolism|down regulation of phosphatidylglycerol anabolism						dgf	2012-09-12T20:47:53Z						biological_process											owl:Class	
GO:2000843	biolink:NamedThing	regulation of testosterone secretion	Any process that modulates the frequency, rate or extent of testosterone secretion.	got7fsn_ti							bf	2011-07-26T08:42:29Z						biological_process											owl:Class	
GO:1903164	biolink:NamedThing	obsolete succinate transmembrane transporter activity involved in succinate import into cell	OBSOLETE. Any succinate transmembrane transporter activity that is involved in succinate import into cell.	got7fsn_ti	dicarboxylate (succinate/fumarate/malate) antiporter activity involved in succinate import into cell|succinate transmembrane transporter activity involved in succinate import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:55Z		True				molecular_function											owl:Class	
GO:0052499	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0043931	biolink:NamedThing	ossification involved in bone maturation	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.	got7fsn_ti	ossification involved in bone modeling|ossification involved in skeletal development													biological_process											owl:Class	
GO:0009402	biolink:NamedThing	obsolete toxin resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	toxin resistance			GO:0009636	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0016943	biolink:NamedThing	obsolete RNA polymerase I transcription elongation factor activity	OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase I following transcription initiation.	got7fsn_ti	Pol I transcription elongation factor activity|RNA polymerase I transcription elongation factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006362				True				molecular_function											owl:Class	
GO:1902563	biolink:NamedThing	regulation of neutrophil activation	Any process that modulates the frequency, rate or extent of neutrophil activation.	got7fsn_ti							ecu	2013-12-10T15:33:08Z						biological_process											owl:Class	
GO:0051138	biolink:NamedThing	positive regulation of NK T cell differentiation	Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation.	got7fsn_ti	positive regulation of NK T-cell differentiation|stimulation of NK T cell differentiation|up-regulation of NK T cell differentiation|positive regulation of NKT cell differentiation|activation of NK T cell differentiation|positive regulation of NK T lymphocyte differentiation|positive regulation of natural killer T cell differentiation|upregulation of NK T cell differentiation|positive regulation of NK T cell development|positive regulation of NK T-lymphocyte differentiation|positive regulation of natural T cell differentiation|up regulation of NK T cell differentiation|positive regulation of NT cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0051074	biolink:NamedThing	obsolete protein tetramerization activity	OBSOLETE. The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.	got7fsn_ti	protein tetramerization activity			GO:0051262	This term was made obsolete because it represents a process.					True				molecular_function											owl:Class	
GO:1900548	biolink:NamedThing	heme B catabolic process	The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.	got7fsn_ti	heme B catabolism|heme B breakdown|heme B degradation|protoheme catabolic process|protoheme degradation						pr	2012-05-14T12:35:18Z				MetaCyc:PWY-5874		biological_process											owl:Class	
GO:2000901	biolink:NamedThing	cyclodextrin catabolic process	The chemical reactions and pathways resulting in the breakdown of a cyclodextrin.	got7fsn_ti	cyclodextrin catabolism						jl	2011-07-28T03:19:13Z						biological_process											owl:Class	
GO:0072751	biolink:NamedThing	cellular response to L-thialysine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.	got7fsn_ti	cellular response to thialysine						mah	2012-09-10T14:12:21Z						biological_process											owl:Class	
GO:0034393	biolink:NamedThing	positive regulation of smooth muscle cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.	got7fsn_ti	up-regulation of smooth muscle cell apoptosis|stimulation of smooth muscle cell apoptosis|positive regulation of smooth muscle cell apoptosis|up regulation of smooth muscle cell apoptosis|positive regulation of SMC apoptosis|upregulation of smooth muscle cell apoptosis|activation of smooth muscle cell apoptosis													biological_process											owl:Class	
GO:0101029	biolink:NamedThing	negative regulation of liquid surface tension	Any process that prevents or reduces the surface tension of a liquid.	got7fsn_ti	negative regulation of surface tension of a liquid													biological_process											owl:Class	
GO:1905351	biolink:NamedThing	pericyte cell migration	The orderly movement of a pericyte cell from one site to another.	got7fsn_ti							rph	2016-08-05T12:01:48Z						biological_process											owl:Class	
GO:1900855	biolink:NamedThing	regulation of fumitremorgin B biosynthetic process	Any process that modulates the frequency, rate or extent of fumitremorgin B biosynthetic process.	got7fsn_ti	regulation of Lanosulin biosynthetic process|regulation of Lanosulin formation|regulation of fumitremorgin B biosynthesis|regulation of Lanosulin anabolism|regulation of fumitremorgin B anabolism|regulation of fumitremorgin B formation|regulation of Lanosulin biosynthesis|regulation of fumitremorgin B synthesis|regulation of Lanosulin synthesis						di	2012-06-07T09:50:37Z						biological_process											owl:Class	
GO:1905418	biolink:NamedThing	positive regulation of amoeboid sperm motility	Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility.	got7fsn_ti	positive regulation of ameboid sperm motility|up-regulation of amoeboid sperm motility|upregulation of ameboid sperm movement|activation of amoeboid sperm motility|positive regulation of amoeboid sperm movement|upregulation of ameboid sperm motility|up regulation of ameboid sperm motility|up regulation of amoeboid sperm motility|up regulation of ameboid sperm movement|positive regulation of ameboid sperm movement|up regulation of amoeboid sperm movement|up-regulation of ameboid sperm movement|activation of ameboid sperm motility|activation of ameboid sperm movement|activation of amoeboid sperm movement|upregulation of amoeboid sperm motility|up-regulation of ameboid sperm motility|up-regulation of amoeboid sperm movement|upregulation of amoeboid sperm movement						pr	2016-09-01T11:29:03Z						biological_process											owl:Class	
GO:0042901	biolink:NamedThing	arabinan transmembrane transporter activity	Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0002854	biolink:NamedThing	positive regulation of T cell mediated cytotoxicity directed against tumor cell target	Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.	got7fsn_ti	upregulation of T cell mediated cytotoxicity directed against tumor cell target|up regulation of T cell mediated cytotoxicity directed against tumor cell target|up-regulation of T cell mediated cytotoxicity directed against tumor cell target|activation of T cell mediated cytotoxicity directed against tumor cell target|stimulation of T cell mediated cytotoxicity directed against tumor cell target													biological_process											owl:Class	
GO:0033022	biolink:NamedThing	cyclopentanol catabolic process	The chemical reactions and pathways resulting in the breakdown of cyclopentanol.	got7fsn_ti	cyclopentanol degradation|cyclopentanol breakdown|cyclopentanol catabolism													biological_process											owl:Class	
GO:0016683	biolink:NamedThing	obsolete oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, NAD, NADP or oxygen.	got7fsn_ti	oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016679				True				molecular_function											owl:Class	
GO:0103113	biolink:NamedThing	obsolete glucosyl-oleandomycin-exporting ATPase activity	OBSOLETE. Catalysis of the reaction: glucosyl-oleandomycin + ATP + H2O <=> glucosyl-oleandomycin + ADP + hydrogenphosphate + H+.	got7fsn_ti					This term was obsoleted because it represents a substrate-specific version of the general term GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity.					True		MetaCyc:TRANS-RXN-220		molecular_function											owl:Class	
GO:0060821	biolink:NamedThing	obsolete inactivation of X chromosome by DNA methylation	OBSOLETE. Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22023			This term was obsoleted because it represents a molecular function.	GO:0035514|GO:0009048	dph	2009-08-11T11:02:19Z		True				biological_process											owl:Class	
GO:0042855	biolink:NamedThing	eugenol biosynthetic process	The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.	got7fsn_ti	eugenol biosynthesis|4-allyl-2-methoxyphenol biosynthetic process|eugenol synthesis|eugenol anabolism|4-allyl-2-methoxyphenol biosynthesis|eugenic acid biosynthesis|eugenic acid biosynthetic process|eugenol formation													biological_process											owl:Class	
GO:1903892	biolink:NamedThing	negative regulation of ATF6-mediated unfolded protein response	Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response.	got7fsn_ti	down-regulation of UPR signaling by ATF6 stress sensor|inhibition of ATF6-alpha UPR branch|downregulation of ATF6-alpha UPR branch|inhibition of UPR signaling by ATF6 stress sensor|down-regulation of ATF6-alpha UPR branch|inhibition of ATF6-beta UPR branch|inhibition of ATF6 branch of UPR|inhibition of ATF6 signaling in response to endoplasmic reticulum stress|down regulation of ATF6-beta UPR branch|downregulation of UPR signaling by ATF6 stress sensor|down-regulation of ATF6 signaling in response to endoplasmic reticulum stress|downregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down regulation of ATF6-mediated unfolded protein response|down regulation of ATF6-alpha UPR branch|downregulation of ATF6 signaling in response to endoplasmic reticulum stress|downregulation of ATF6 branch of UPR|negative regulation of ATF6-alpha UPR branch|downregulation of ATF6-beta UPR branch|negative regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down regulation of UPR signaling by ATF6 stress sensor|negative regulation of UPR signaling by ATF6 stress sensor|down regulation of ATF6 branch of UPR|down regulation of ATF6 signaling in response to endoplasmic reticulum stress|negative regulation of ATF6 signaling in response to endoplasmic reticulum stress|inhibition of endoplasmic reticulum unfolded protein response; ATF6 signaling|downregulation of activating transcription factor 6 signaling in unfolded protein response|down regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down regulation of activating transcription factor 6 signaling in unfolded protein response|negative regulation of ATF6 branch of UPR|downregulation of ATF6-mediated unfolded protein response|down-regulation of activating transcription factor 6 signaling in unfolded protein response|down-regulation of ATF6-mediated unfolded protein response|negative regulation of activating transcription factor 6 signaling in unfolded protein response|down-regulation of ATF6 branch of UPR|inhibition of ATF6-mediated unfolded protein response|inhibition of activating transcription factor 6 signaling in unfolded protein response|down-regulation of ATF6-beta UPR branch|negative regulation of ATF6-beta UPR branch|down-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling						bf	2015-02-09T10:17:26Z						biological_process											owl:Class	
GO:0039597	biolink:NamedThing	obsolete induction by virus of host endoribonuclease activity	OBSOLETE. Any viral process that activates or increases the frequency, rate or extent of host endoribonuclease activity.	got7fsn_ti	viral induction of host RNAse activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.		bf	2012-07-04T04:36:49Z		True				biological_process											owl:Class	
GO:0034373	biolink:NamedThing	intermediate-density lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.	got7fsn_ti	IDL remodeling|low-density lipoprotein particle formation|LDL formation													biological_process											owl:Class	
GO:1900461	biolink:NamedThing	positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti							dgf	2012-05-01T07:01:40Z						biological_process											owl:Class	
CHEBI:27732	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048021	biolink:NamedThing	regulation of melanin biosynthetic process	Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.	got7fsn_ti	regulation of melanin anabolism|regulation of melanin synthesis|regulation of melanin formation|regulation of melanin biosynthesis													biological_process											owl:Class	
GO:0032849	biolink:NamedThing	positive regulation of cellular pH reduction	Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.	got7fsn_ti	stimulation of cellular pH reduction|positive regulation of intracellular pH reduction|up-regulation of cellular pH reduction|positive regulation of cellular acidification|up regulation of cellular pH reduction|positive regulation of intracellular acidification|upregulation of cellular pH reduction|activation of cellular pH reduction|positive regulation of reduction of cellular pH|positive regulation of reduction of pH in cell|positive regulation of cell pH reduction													biological_process											owl:Class	
GO:0005108	biolink:NamedThing	obsolete transmembrane ephrin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transmembrane ephrin				This term was made obsolete because it refers to a class of gene products.	GO:0005887|GO:0046875				True				molecular_function											owl:Class	
GO:0006016	biolink:NamedThing	2-deoxyribose 1-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.	got7fsn_ti	2-deoxyribose 1-phosphate formation|2-deoxyribose 1-phosphate biosynthesis|2-deoxyribose 1-phosphate anabolism|2-deoxyribose 1-phosphate synthesis													biological_process											owl:Class	
GO:1904807	biolink:NamedThing	negative regulation of protein oxidation	Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation.	got7fsn_ti	down regulation of protein oxidation|downregulation of protein oxidation|negative regulation of protein amino acid oxidation|down-regulation of protein amino acid oxidation|downregulation of protein amino acid oxidation|inhibition of protein amino acid oxidation|down regulation of protein amino acid oxidation|down-regulation of protein oxidation|inhibition of protein oxidation						mec	2015-11-10T14:06:08Z						biological_process											owl:Class	
UBERON:0001178	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046079	biolink:NamedThing	dUMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate.	got7fsn_ti	dUMP degradation|dUMP breakdown|dUMP catabolism													biological_process											owl:Class	
GO:1902565	biolink:NamedThing	positive regulation of neutrophil activation	Any process that activates or increases the frequency, rate or extent of neutrophil activation.	got7fsn_ti	activation of neutrophil activation|upregulation of neutrophil activation|up-regulation of neutrophil activation|up regulation of neutrophil activation						ecu	2013-12-10T15:33:26Z						biological_process											owl:Class	
GO:0070895	biolink:NamedThing	negative regulation of transposon integration	Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.	got7fsn_ti	downregulation of transposon integration|inhibition of transposon integration|down regulation of transposon integration|down-regulation of transposon integration						mah	2009-09-01T04:20:36Z						biological_process											owl:Class	
GO:1901420	biolink:NamedThing	negative regulation of response to alcohol	Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.	got7fsn_ti	downregulation of response to alcohol|down-regulation of response to alcohol|down regulation of response to alcohol|inhibition of response to alcohol						tt	2012-10-01T16:53:25Z						biological_process											owl:Class	
GO:2000013	biolink:NamedThing	regulation of arginine biosynthetic process via ornithine	Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine.	got7fsn_ti	regulation of arginine formation via ornithine|regulation of arginine anabolism via ornithine|regulation of arginine synthesis via ornithine						tb	2010-08-05T11:21:51Z						biological_process											owl:Class	
GO:1901082	biolink:NamedThing	positive regulation of relaxation of smooth muscle	Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle.	got7fsn_ti	upregulation of relaxation of smooth muscle|up regulation of relaxation of smooth muscle|upregulation of smooth muscle relaxation|up-regulation of relaxation of smooth muscle|positive regulation of smooth muscle relaxation|activation of relaxation of smooth muscle|activation of smooth muscle relaxation|up-regulation of smooth muscle relaxation|up regulation of smooth muscle relaxation						jl	2012-07-04T10:45:39Z						biological_process											owl:Class	
GO:0085005	biolink:NamedThing	obsolete interaction with host via secreted substance released from invasive hyphae	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via invasive hyphae. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T02:59:51Z		True				biological_process											owl:Class	
GO:0008156	biolink:NamedThing	negative regulation of DNA replication	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.	got7fsn_ti	down regulation of DNA replication|downregulation of DNA replication|DNA replication inhibitor|down-regulation of DNA replication|inhibition of DNA replication													biological_process											owl:Class	
GO:1905183	biolink:NamedThing	negative regulation of protein serine/threonine phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity.	got7fsn_ti	down regulation of serine/threonine specific protein phosphatase activity|down-regulation of protein serine/threonine phosphatase activity|downregulation of protein serine/threonine phosphatase activity|inhibition of protein serine/threonine phosphatase activity|negative regulation of serine/threonine specific protein phosphatase activity|down-regulation of serine/threonine specific protein phosphatase activity|inhibition of serine/threonine specific protein phosphatase activity|downregulation of serine/threonine specific protein phosphatase activity|down regulation of protein serine/threonine phosphatase activity						mah	2016-05-10T15:28:04Z						biological_process											owl:Class	
GO:1901372	biolink:NamedThing	obsolete trehalose biosynthetic process involved in ascospore formation	OBSOLETE. Any trehalose biosynthetic process that is involved in ascospore formation.	got7fsn_ti	mykose biosynthetic process involved in ascospore formation|trehalose synthesis involved in ascospore formation|trehalose biosynthesis involved in ascospore formation|mycose biosynthetic process involved in ascospore biosynthesis|mykose biosynthesis involved in ascospore formation|trehalose synthesis involved in ascospore biosynthesis|trehalose biosynthesis involved in ascospore biosynthesis|mycose biosynthesis involved in ascospore formation|trehalose anabolism involved in ascospore formation|mykose biosynthetic process involved in ascospore biosynthesis|mycose biosynthesis involved in ascospore biosynthesis|trehalose formation involved in ascospore biosynthesis|trehalose anabolism involved in ascospore biosynthesis|mykose biosynthesis involved in ascospore biosynthesis|trehalose formation involved in ascospore formation|mycose biosynthetic process involved in ascospore formation|trehalose biosynthetic process involved in ascospore biosynthesis	https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.		al	2012-09-25T11:06:48Z		True				biological_process											owl:Class	
GO:0045805	biolink:NamedThing	positive regulation of eclosion	Any process that activates or increases the frequency, rate or extent of eclosion.	got7fsn_ti	activation of eclosion|up-regulation of eclosion|upregulation of eclosion|up regulation of eclosion|stimulation of eclosion													biological_process											owl:Class	
GO:0006176	biolink:NamedThing	dATP biosynthetic process from ADP	The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate.	got7fsn_ti	dATP synthesis from ADP|dATP formation from ADP|dATP anabolism from ADP													biological_process											owl:Class	
GO:0008369	biolink:NamedThing	obsolete molecular function	OBSOLETE. These are terms that have been removed from the active function ontology.	got7fsn_ti					This term was made obsolete because it is unnecessary in the OBO flat file format.					True				molecular_function											owl:Class	
GO:1900423	biolink:NamedThing	obsolete positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching.	got7fsn_ti	stimulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|up regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|activation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|up-regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|upregulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-24T05:50:51Z		True				biological_process											owl:Class	
GO:0061424	biolink:NamedThing	obsolete positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of peroxisome organization.	got7fsn_ti	positive regulation of peroxisome organisation by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dph	2012-02-02T12:50:36Z		True				biological_process											owl:Class	
GO:0075165	biolink:NamedThing	obsolete regulation of G-protein gamma subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0035009	biolink:NamedThing	negative regulation of melanization defense response	Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.	got7fsn_ti	down-regulation of melanization defense response|negative regulation of melanization defence response|downregulation of melanization defense response|down regulation of melanization defense response|inhibition of melanization defense response													biological_process											owl:Class	
GO:0006255	biolink:NamedThing	obsolete UDP reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	UDP reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051062				True				biological_process											owl:Class	
GO:1900844	biolink:NamedThing	negative regulation of monodictyphenone biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process.	got7fsn_ti	down regulation of monodictyphenone biosynthetic process|down-regulation of monodictyphenone biosynthetic process|downregulation of monodictyphenone biosynthetic process						di	2012-06-07T09:41:00Z						biological_process											owl:Class	
GO:1900467	biolink:NamedThing	obsolete regulation of cellular potassium ion homeostasis	OBSOLETE. Any process that modulates the frequency, rate or extent of cellular potassium ion homeostasis.	got7fsn_ti	regulation of cellular potassium ion homeostasis				This term was obsoleted at the TermGenie Gatekeeper stage.		dgf	2012-05-01T07:48:07Z		True				biological_process											owl:Class	
GO:1902822	biolink:NamedThing	regulation of late endosome to lysosome transport	Any process that modulates the frequency, rate or extent of late endosome to lysosome transport.	got7fsn_ti	regulation of prevacuolar compartment to lysosome transport						pad	2014-03-31T10:08:38Z						biological_process											owl:Class	
GO:2000512	biolink:NamedThing	negative regulation of granzyme A production	Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production.	got7fsn_ti							ebc	2011-03-22T10:31:32Z						biological_process											owl:Class	
GO:0010268	biolink:NamedThing	brassinosteroid homeostasis	Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:1904635	biolink:NamedThing	positive regulation of glomerular visceral epithelial cell apoptotic process	Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.	got7fsn_ti	up regulation of glomerular visceral epithelial cell apoptosis|up-regulation of glomerular visceral epithelial cell apoptotic process|up-regulation of podocyte apoptosis|up-regulation of glomerular visceral epithelial cell apoptosis|upregulation of glomerular visceral epithelial cell apoptosis|activation of glomerular podocyte apoptosis|activation of glomerular podocyte apoptotic process|up regulation of podocyte apoptosis|positive regulation of glomerular visceral epithelial cell apoptosis|upregulation of podocyte apoptotic process|up-regulation of glomerular podocyte apoptosis|up regulation of glomerular podocyte apoptotic process|upregulation of glomerular podocyte apoptosis|positive regulation of glomerular podocyte apoptotic process|upregulation of podocyte apoptosis|up-regulation of glomerular podocyte apoptotic process|up regulation of podocyte apoptotic process|activation of podocyte apoptotic process|upregulation of glomerular visceral epithelial cell apoptotic process|positive regulation of glomerular podocyte apoptosis|up-regulation of podocyte apoptotic process|activation of glomerular visceral epithelial cell apoptosis|activation of podocyte apoptosis|up regulation of glomerular podocyte apoptosis|positive regulation of podocyte apoptosis|positive regulation of podocyte apoptotic process|up regulation of glomerular visceral epithelial cell apoptotic process|activation of glomerular visceral epithelial cell apoptotic process|upregulation of glomerular podocyte apoptotic process						sl	2015-08-28T14:14:56Z						biological_process											owl:Class	
GO:1905708	biolink:NamedThing	regulation of cell morphogenesis involved in conjugation with cellular fusion	Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion.	got7fsn_ti	regulation of shmoo orientation|regulation of shmooing						mah	2016-11-18T11:33:54Z						biological_process											owl:Class	
GO:1901706	biolink:NamedThing	mesenchymal cell differentiation involved in bone development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state.	got7fsn_ti							hjd	2012-12-14T16:04:16Z						biological_process											owl:Class	
GO:1901444	biolink:NamedThing	positive regulation of response to furfural	Any process that activates or increases the frequency, rate or extent of response to furfural.	got7fsn_ti	activation of response to furfural|up regulation of response to furfural|upregulation of response to furfural|up-regulation of response to furfural						tt	2012-10-02T14:10:51Z						biological_process											owl:Class	
PR:000001498	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0106038	biolink:NamedThing	obsolete vesicle assembly	OBSOLETE. A process carried out at the cellular level, which results in the arrangement of constituent parts of a vesicle. Vesicle assembly begins with membrane bending (GO:0097753) and ends with fusion of the vesicle after vesicle scission (GO:0099050).	got7fsn_ti	vesicle biosynthesis|vesicle formation				This term was made obsolete because it is an exact synonym of 'membrane budding'.		hjd	2017-07-17T13:52:28Z		True				biological_process											owl:Class	
GO:1905582	biolink:NamedThing	response to mannose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.	got7fsn_ti							pga	2016-10-21T11:40:40Z						biological_process											owl:Class	
GO:0001026	biolink:NamedThing	obsolete TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	got7fsn_ti	RNA polymerase III recruiting transcription factor activity				This term was obsoleted because it represents a gene product.		krc	2010-08-23T12:24:31Z		True				molecular_function											owl:Class	
GO:1902145	biolink:NamedThing	regulation of response to cell cycle checkpoint signaling	Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling.	got7fsn_ti	regulation of G1/S transition checkpoint effector process|regulation of response to signal involved in G1/S transition checkpoint|regulation of response to G2/M transition checkpoint signaling|regulation of G2/M transition checkpoint effector process|regulation of cell cycle checkpoint effector process|regulation of response to signal involved in G2/M transition checkpoint|regulation of response to G1/S transition checkpoint signaling|regulation of response to signal involved in cell cycle checkpoint						jl	2013-05-21T15:43:40Z						biological_process											owl:Class	
GO:1902817	biolink:NamedThing	negative regulation of protein localization to microtubule	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.	got7fsn_ti	downregulation of protein localisation to microtubule|inhibition of protein localization to microtubule|downregulation of protein localization to microtubule|down-regulation of protein localization to microtubule|down regulation of protein localization to microtubule|negative regulation of protein localisation to microtubule|inhibition of protein localisation to microtubule|down-regulation of protein localisation to microtubule|down regulation of protein localisation to microtubule						tb	2014-03-27T22:07:18Z						biological_process											owl:Class	
GO:0100013	biolink:NamedThing	obsolete positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates fatty acid beta-oxidation.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1901492	biolink:NamedThing	positive regulation of lymphangiogenesis	Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.	got7fsn_ti	activation of lymphangiogenesis|activation of lymph vessel formation|up-regulation of lymphangiogenesis|upregulation of lymph vessel formation|up regulation of lymphangiogenesis|positive regulation of lymph vessel formation|up regulation of lymph vessel formation|upregulation of lymphangiogenesis|up-regulation of lymph vessel formation						dph	2012-10-15T13:08:25Z						biological_process											owl:Class	
UBERON:0003214	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901910	biolink:NamedThing	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process	The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate).	got7fsn_ti	adenosine 5'-(hexahydrogen pentaphosphate) metabolism						al	2013-02-13T14:17:59Z						biological_process											owl:Class	
GO:0008956	biolink:NamedThing	obsolete peptidyl-dipeptidase Dcp activity	OBSOLETE. Catalysis of the hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly.	got7fsn_ti	dipeptidyl carboxypeptidase activity|peptidyl-dipeptidase Dcp activity|dipeptidyl carboxypeptidase (Dcp)				This term was made obsolete because it represents a gene product.	GO:0008235|GO:0008241				True		EC:3.4.15.5|MetaCyc:3.4.15.5-RXN		molecular_function											owl:Class	
GO:0019269	biolink:NamedThing	obsolete glutamate biosynthetic process, using glutamate synthase (NADPH)	OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate synthase (NADPH).	got7fsn_ti	glutamate anabolism, using glutamate synthase (NADPH)|glutamate formation, using glutamate synthase (NADPH)|glutamate biosynthetic process, using glutamate synthase (NADPH)|glutamate synthesis, using glutamate synthase (NADPH)				This term was made obsolete because it refers to a molecular function.	GO:0006537|GO:0004355				True				biological_process											owl:Class	
GO:1904575	biolink:NamedThing	positive regulation of selenocysteine insertion sequence binding	Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding.	got7fsn_ti	upregulation of selenocysteine insertion sequence binding|upregulation of SECIS binding|positive regulation of SECIS binding|up-regulation of selenocysteine insertion sequence binding|up regulation of selenocysteine insertion sequence binding|activation of SECIS binding|up regulation of SECIS binding|up-regulation of SECIS binding|activation of selenocysteine insertion sequence binding						sl	2015-08-19T17:51:21Z						biological_process											owl:Class	
GO:0099601	biolink:NamedThing	regulation of neurotransmitter receptor activity	Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.	got7fsn_ti														biological_process											owl:Class	
GO:2001131	biolink:NamedThing	methane biosynthetic process from dimethyl sulfide	The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide.	got7fsn_ti							jl	2011-10-13T10:44:31Z						biological_process											owl:Class	
GO:0042850	biolink:NamedThing	L-sorbose catabolic process	The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose.	got7fsn_ti	L-sorbose breakdown|L-sorbose degradation|L-sorbose catabolism													biological_process											owl:Class	
GO:0090723	biolink:NamedThing	obsolete growth cone part	OBSOLETE. Any constituent part of a growth cone, the migrating motile tip of a growing nerve cell axon or dendrite.	got7fsn_ti						GO:0030426	tb	2016-11-18T09:36:19Z		True				cellular_component											owl:Class	
GO:0031936	biolink:NamedThing	obsolete negative regulation of chromatin silencing	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.	got7fsn_ti	downregulation of chromatin silencing|inhibition of chromatin silencing|loss of chromatin silencing|down regulation of chromatin silencing|down-regulation of chromatin silencing|negative regulation of heterochromatic silencing	https://github.com/geneontology/go-ontology/issues/22060			This term was obsoleted because it was too vague: regulation of chromatin (gene) silencing takes place via upstream signaling pathways.					True	GO:0006345			biological_process											owl:Class	
GO:0015305	biolink:NamedThing	obsolete lactose, galactose:proton symporter activity	OBSOLETE. Catalysis of the reaction: (lactose or galactose)(out) + H+(out) = (lactose or galactose)(in) + H+(in).	got7fsn_ti	lactose,galactose:proton symporter activity|lactose, galactose:proton symporter activity|lactose, galactose:hydrogen symporter activity				This term was made obsolete because it represents two molecular functions.	GO:0015528|GO:0015517				True				molecular_function											owl:Class	
GO:1902317	biolink:NamedThing	nuclear DNA replication termination	Any DNA replication termination that is involved in nuclear cell cycle DNA replication.	got7fsn_ti	DNA replication termination involved in DNA replication involved in S-phase|DNA replication termination involved in nuclear cell cycle DNA replication|DNA replication termination involved in DNA replication during S phase|DNA replication termination involved in DNA replication involved in S phase						jl	2013-07-23T14:00:17Z						biological_process											owl:Class	
GO:0070373	biolink:NamedThing	negative regulation of ERK1 and ERK2 cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.	got7fsn_ti	inhibition of ERK1 and ERK2 cascade|down regulation of ERK1 and ERK2 cascade|negative regulation of MAPK3 cascade|downregulation of ERK1 and ERK2 cascade|negative regulation of ERK2 cascade|negative regulation of ERK1 and ERK2 signalling pathway|negative regulation of ERK1/2 cascade|negative regulation of ERK cascade|down-regulation of ERK1 and ERK2 cascade|negative regulation of ERK1 cascade|negative regulation of ERK1 and ERK2 signaling pathway|negative regulation of MAPK1 cascade													biological_process											owl:Class	
GO:0071686	biolink:NamedThing	obsolete horsetail nucleus	OBSOLETE. The elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.	got7fsn_ti					This term was made obsolete at the request of PomBase as the concept can be expressed by annotating to a less granular term and using annotation extensions.		mah	2010-02-22T04:52:01Z		True				cellular_component											owl:Class	
GO:0036255	biolink:NamedThing	response to methylamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.	got7fsn_ti							bf	2012-06-15T01:07:27Z						biological_process											owl:Class	
GO:0031620	biolink:NamedThing	regulation of fever generation	Any process that modulates the rate or extent of fever generation.	got7fsn_ti	regulation of pyrexia													biological_process											owl:Class	
GO:1905173	biolink:NamedThing	eukaryotic translation initiation factor 2B complex assembly	The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex.	got7fsn_ti	eIF-2B assembly|eIF-2B formation|eukaryotic translation initiation factor 2B complex formation|eif2B formation|eif2B assembly						mah	2016-05-03T11:00:21Z						biological_process											owl:Class	
GO:0071866	biolink:NamedThing	negative regulation of apoptotic process in bone marrow cell	Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.	got7fsn_ti	negative regulation of programmed cell death, bone marrow cells|negative regulation of bone marrow cell programmed cell death by apoptosis|negative regulation of bone marrow cell apoptosis|downregulation of apoptosis in bone marrow|down-regulation of apoptosis in bone marrow|inhibition of apoptosis in bone marrow|negative regulation of apoptosis in bone marrow|negative regulation of apoptotic process in bone marrow|negative regulation of killing of bone marrow cells|down regulation of apoptosis in bone marrow|negative regulation of programmed cell death of bone marrow cells by apoptosis						mah	2010-09-13T02:17:38Z						biological_process											owl:Class	
GO:0034195	biolink:NamedThing	L-galactonate catabolic process	The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid.	got7fsn_ti	L-galactonate breakdown|L-galactonate degradation|L-galactonate catabolism											MetaCyc:GALACTCAT-PWY		biological_process											owl:Class	
GO:0086083	biolink:NamedThing	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	Binding to a protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells.	got7fsn_ti							dph	2011-11-22T11:11:03Z						molecular_function											owl:Class	
GO:0010157	biolink:NamedThing	response to chlorate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:1901506	biolink:NamedThing	regulation of acylglycerol transport	Any process that modulates the frequency, rate or extent of acylglycerol transport.	got7fsn_ti	regulation of glyceride transport						sart	2012-10-17T11:06:10Z						biological_process											owl:Class	
GO:0002037	biolink:NamedThing	negative regulation of L-glutamate import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell.	got7fsn_ti	down regulation of L-glutamate transport|down regulation of L-glutamate import|down regulation of L-glutamate uptake|inhibition of L-glutamate uptake|negative regulation of L-glutamate uptake|inhibition of L-glutamate transport|down-regulation of L-glutamate transport|negative regulation of L-glutamate transport|downregulation of L-glutamate uptake|downregulation of L-glutamate transport|down-regulation of L-glutamate uptake|inhibition of L-glutamate import|regulation of L-glutamate import|downregulation of L-glutamate import|negative regulation of L-glutamate import|down-regulation of L-glutamate import						al	2012-06-13T07:34:30Z			GO:1900921			biological_process											owl:Class	
GO:0030293	biolink:NamedThing	transmembrane receptor protein tyrosine kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase.	got7fsn_ti														molecular_function											owl:Class	
GO:1903292	biolink:NamedThing	protein localization to Golgi membrane	A process in which a protein is transported to, or maintained in, a location within a Golgi membrane.	got7fsn_ti	protein localisation in Golgi membrane|protein localisation to Golgi membrane|protein localization in Golgi membrane						mah	2014-08-12T14:22:31Z						biological_process											owl:Class	
GO:0009502	biolink:NamedThing	obsolete photosynthetic electron transport chain	OBSOLETE. A series of membrane-linked oxidation-reduction reactions in which electrons are transferred from an initial electron donor through a series of intermediates to a final electron acceptor (usually oxygen).	got7fsn_ti	photosynthetic electron transport chain				This term was made obsolete because it represents a process.	GO:0009767				True				cellular_component											owl:Class	
GO:1902128	biolink:NamedThing	(-)-lariciresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol.	got7fsn_ti	(-)-lariciresinol degradation|(-)-lariciresinol catabolism|(-)-lariciresinol breakdown						ms	2013-05-21T08:49:38Z						biological_process											owl:Class	
GO:1902932	biolink:NamedThing	positive regulation of alcohol biosynthetic process	Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process.	got7fsn_ti	activation of alcohol biosynthetic process|positive regulation of alcohol anabolism|up regulation of alcohol formation|up-regulation of alcohol synthesis|up-regulation of alcohol biosynthesis|up regulation of alcohol synthesis|up-regulation of alcohol anabolism|upregulation of alcohol synthesis|up-regulation of alcohol biosynthetic process|positive regulation of alcohol biosynthesis|positive regulation of solventogenesis|up regulation of alcohol biosynthetic process|positive regulation of alcohol synthesis|up-regulation of alcohol formation|activation of alcohol formation|upregulation of alcohol formation|activation of alcohol biosynthesis|upregulation of alcohol biosynthetic process|activation of alcohol synthesis|positive regulation of alcohol formation|activation of alcohol anabolism|up regulation of alcohol biosynthesis|upregulation of alcohol biosynthesis|up regulation of alcohol anabolism|upregulation of alcohol anabolism						tt	2014-04-22T21:55:19Z						biological_process											owl:Class	
GO:0050444	biolink:NamedThing	obsolete aquacobalamin reductase (NADPH) activity	OBSOLETE. Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+.	got7fsn_ti	NADPH2:aquacob(III)alamin oxidoreductase activity|cob(II)alamin:NADP+ oxidoreductase activity|NADPH-linked aquacobalamin reductase activity|aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) activity|NADPH:aquacob(III)alamin oxidoreductase activity|aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase activity	https://github.com/geneontology/go-ontology/issues/20679			The term was obsoleted because it is not known to be catalyzed by any gene product.					True		RHEA:20752|EC:1.16.1.5|MetaCyc:AQUACOBALAMIN-REDUCTASE-NADPH-RXN		molecular_function											owl:Class	
GO:0019698	biolink:NamedThing	D-galacturonate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.	got7fsn_ti	D-galacturonate breakdown|D-galacturonate catabolism|D-galacturonate degradation											MetaCyc:GALACTUROCAT-PWY		biological_process											owl:Class	
GO:0075303	biolink:NamedThing	positive regulation of basidiospore formation	Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.	got7fsn_ti														biological_process											owl:Class	
GO:1901747	biolink:NamedThing	prephenate(2-) biosynthetic process	The chemical reactions and pathways resulting in the formation of prephenate(2-).	got7fsn_ti	prephenate(2-) biosynthesis|prephenate anabolism|prephenate(2-) formation|prephenate(2-) anabolism|prephenate(2-) synthesis|prephenate synthesis|prephenate biosynthesis|prephenate formation						yaf	2013-01-14T10:13:57Z						biological_process											owl:Class	
GO:0019264	biolink:NamedThing	glycine biosynthetic process from serine	The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine.	got7fsn_ti	glycine anabolism from serine|glycine synthesis from serine|glycine formation from serine											MetaCyc:GLYSYN-PWY		biological_process											owl:Class	
GO:0004228	biolink:NamedThing	obsolete gelatinase A activity	OBSOLETE. Catalysis of the cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-Ile-Ala-Gly-Gln at the Gly-Ile bond.	got7fsn_ti	matrix metalloproteinase 2 activity|72-kDa gelatinase activity|type IV collagenase activity|type IV collagen metalloproteinase|72 kDa gelatinase type A|collagenase type IV|MMP 2|collagenase IV|3/4 collagenase activity|MMP-2|matrix metalloproteinase 5|gelatinase A activity|type IV collagenase/gelatinase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0000757	biolink:NamedThing	obsolete signal transduction involved in regulation of conjugation with mutual genetic exchange	OBSOLETE. A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion.	got7fsn_ti	signal transduction involved in conjugation without cellular fusion	https://github.com/geneontology/go-ontology/issues/15815			This term was obsoleted because its label and definitions were not clear. It had never been used for annotation.					True				biological_process											owl:Class	
CHEBI:28097	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075056	biolink:NamedThing	obsolete negative regulation of penetration peg formation	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont penetration peg initiation|negative regulation of symbiont penetration peg formation for entry into host	https://github.com/geneontology/go-ontology/issues/18779			This term was obsoleted because there is no evidence that this process exists.					True	GO:0075060			biological_process											owl:Class	
GO:1902325	biolink:NamedThing	negative regulation of chlorophyll biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process.	got7fsn_ti	down regulation of chlorophyll synthesis|down-regulation of chlorophyll biosynthesis|down regulation of chlorophyll anabolism|downregulation of chlorophyll biosynthetic process|down regulation of chlorophyll biosynthetic process|downregulation of chlorophyll synthesis|inhibition of chlorophyll biosynthesis|negative regulation of chlorophyll anabolism|down regulation of chlorophyll biosynthesis|downregulation of chlorophyll formation|inhibition of chlorophyll synthesis|down regulation of chlorophyll formation|negative regulation of chlorophyll synthesis|downregulation of chlorophyll biosynthesis|negative regulation of chlorophyll biosynthesis|down-regulation of chlorophyll synthesis|down-regulation of chlorophyll biosynthetic process|inhibition of chlorophyll formation|inhibition of chlorophyll biosynthetic process|down-regulation of chlorophyll formation|negative regulation of chlorophyll formation|downregulation of chlorophyll anabolism|inhibition of chlorophyll anabolism|down-regulation of chlorophyll anabolism						tb	2013-07-24T22:47:29Z						biological_process											owl:Class	
GO:2000749	biolink:NamedThing	positive regulation of rDNA heterochromatin assembly	Any process that activates or increases the frequency, rate or extent of assembly of rDNA heterochromatin.	got7fsn_ti	positive regulation of chromatin silencing at rDNA|positive regulation of heterochromatic silencing at rDNA|positive regulation of ribosomal DNA heterochromatin assembly|positive regulation of rDNA chromatin silencing|positive regulation of chromatin silencing at ribosomal DNA	https://github.com/geneontology/go-ontology/issues/19238					pr	2011-06-16T09:43:55Z						biological_process											owl:Class	
GO:1903451	biolink:NamedThing	negative regulation of G1 to G0 transition	Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition.	got7fsn_ti	inhibition of G1/G0 transition|down regulation of G1/G0 transition|downregulation of cell cycle quiescence|downregulation of G1/G0 transition|downregulation of G1 to G0 transition|inhibition of stationary phase|down-regulation of establishment of cell quiescence|downregulation of stationary phase|down-regulation of G1 to G0 transition|downregulation of establishment of cell quiescence|negative regulation of G1/G0 transition|down regulation of G1 to G0 transition|inhibition of establishment of cell quiescence|inhibition of G1 to G0 transition|down regulation of establishment of cell quiescence|negative regulation of stationary phase|down-regulation of G1/G0 transition|down regulation of cell cycle quiescence|negative regulation of cell cycle quiescence|inhibition of cell cycle quiescence|down regulation of stationary phase|negative regulation of establishment of cell quiescence|down-regulation of stationary phase|down-regulation of cell cycle quiescence						di	2014-09-19T22:23:22Z						biological_process											owl:Class	
CHEBI:57756	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042049	biolink:NamedThing	cellular acyl-CoA homeostasis	Any process involved in the maintenance of an internal steady state of acyl-CoA within a cell or between a cell and its external environment.	got7fsn_ti	cell acyl-CoA homeostasis													biological_process											owl:Class	
GO:0052477	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont callose deposition	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of callose deposition performed by the symbiont as part of its defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	suppression by organism of defense-related symbiont callose deposition|negative regulation by organism of defense-related symbiont callose deposition				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0000198	biolink:NamedThing	obsolete activation of MAPKK activity involved in cell wall organization or biogenesis	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of cell wall organization or biogenesis.	got7fsn_ti	activation of MAPKK activity involved in cell wall biogenesis|cell wall biogenesis, activation of MAP kinase kinase activity|activation of MAPKK activity involved in cell wall integrity|cell wall biogenesis, activation of MAPKK activity|activation of MAP kinase kinase activity during cell wall biogenesis	https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0008247	biolink:NamedThing	1-alkyl-2-acetylglycerophosphocholine esterase complex	An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF).	got7fsn_ti	2-acetyl-1-alkylglycerophosphocholine esterase complex|platelet-activating factor acetylhydrolase complex				See also the molecular function term '1-alkyl-2-acetylglycerophosphocholine esterase activity ; GO:0003847'.									cellular_component											owl:Class	
GO:0006774	biolink:NamedThing	obsolete vitamin B12 reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	vitamin B12 reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0050453|GO:0009235				True				biological_process											owl:Class	
GO:1905835	biolink:NamedThing	cellular response to pyrimidine ribonucleotide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.	got7fsn_ti							sl	2017-01-17T19:24:09Z						biological_process											owl:Class	
GO:0150032	biolink:NamedThing	positive regulation of protein localization to lysosome	Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.	got7fsn_ti							bc	2018-02-06T17:11:02Z						biological_process											owl:Class	
GO:0106134	biolink:NamedThing	positive regulation of cardiac muscle cell contraction	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction.	got7fsn_ti							hjd	2018-07-26T16:05:16Z						biological_process											owl:Class	
GO:0051462	biolink:NamedThing	regulation of cortisol secretion	Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0090049	biolink:NamedThing	regulation of cell migration involved in sprouting angiogenesis	Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.	got7fsn_ti							tb	2009-08-07T10:37:16Z						biological_process											owl:Class	
GO:1900992	biolink:NamedThing	(-)-secologanin metabolic process	The chemical reactions and pathways involving (-)-secologanin.	got7fsn_ti	(-)-secologanin metabolism						yaf	2012-06-14T09:51:17Z						biological_process											owl:Class	
GO:0042798	biolink:NamedThing	obsolete protein neddylation during NEDD8 class-dependent protein catabolic process	OBSOLETE. Covalent attachment of the ubiquitin-like protein NEDD8 (or equivalent protein) to another protein, as a part of NEDD8-dependant protein catabolism.	got7fsn_ti	protein neddylation during NEDD8 class-dependent protein catabolism|protein neddylation during NEDD8 class-dependent protein breakdown|protein neddylation during RUB1-dependent protein catabolism|protein neddylation during NEDD8 class-dependent protein catabolic process|protein neddylation during NEDD8 class-dependent protein degradation|protein neddylation during RUB1-dependent protein catabolic process				This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction.	GO:0045116				True				biological_process											owl:Class	
GO:1905759	biolink:NamedThing	post-anaphase array microtubule	Any microtubule that is part of a post-anaphase microtubule array.	got7fsn_ti	microtubuli of post-anaphase microtubule array|microtubuli of PAA|microtubule of PAA|microtubule of post-anaphase microtubule array|neurotubule of post-anaphase array|microtubule of post-anaphase array|microtubulus of post-anaphase array|microtubulus of PAA|microtubulus of post-anaphase microtubule array|neurotubule of post-anaphase microtubule array|microtubuli of post-anaphase array|neurotubule of PAA						dos	2016-12-12T18:36:53Z						cellular_component											owl:Class	
GO:1900343	biolink:NamedThing	negative regulation of methane biosynthetic process from dimethyl sulfide	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.	got7fsn_ti	down regulation of methane biosynthetic process from dimethyl sulfide|inhibition of methane biosynthetic process from dimethyl sulfide|downregulation of methane biosynthetic process from dimethyl sulfide|down-regulation of methane biosynthetic process from dimethyl sulfide						tt	2012-04-06T02:06:47Z						biological_process											owl:Class	
GO:0002736	biolink:NamedThing	regulation of plasmacytoid dendritic cell cytokine production	Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.	got7fsn_ti														biological_process											owl:Class	
GO:0006248	biolink:NamedThing	CMP catabolic process	The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate.	got7fsn_ti	CMP degradation|CMP catabolism|CMP breakdown													biological_process											owl:Class	
GO:0030809	biolink:NamedThing	negative regulation of nucleotide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.	got7fsn_ti	negative regulation of nucleotide synthesis|negative regulation of nucleotide anabolism|inhibition of nucleotide biosynthetic process|negative regulation of nucleotide formation|negative regulation of nucleotide biosynthesis|downregulation of nucleotide biosynthetic process|down-regulation of nucleotide biosynthetic process|down regulation of nucleotide biosynthetic process													biological_process											owl:Class	
GO:0048775	biolink:NamedThing	regulation of leucophore differentiation	Any process that modulates the frequency, rate or extent of leucophore differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0051345	biolink:NamedThing	positive regulation of hydrolase activity	Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.	got7fsn_ti	stimulation of hydrolase activity|hydrolase activator|up-regulation of hydrolase activity|activation of hydrolase activity|up regulation of hydrolase activity|upregulation of hydrolase activity													biological_process											owl:Class	
GO:0033349	biolink:NamedThing	apiose metabolic process	The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.	got7fsn_ti	apiose metabolism													biological_process											owl:Class	
CHEBI:50723	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902907	biolink:NamedThing	proteasome storage granule disassembly	The disaggregation of a proteasome storage granule into its constituent components.	got7fsn_ti	PSG disassembly						di	2014-04-16T01:59:47Z						biological_process											owl:Class	
GO:0031449	biolink:NamedThing	regulation of slow-twitch skeletal muscle fiber contraction	Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction.	got7fsn_ti	regulation of slow-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:0033625	biolink:NamedThing	positive regulation of integrin activation	Any process that activates or increases the frequency, rate, or extent of integrin activation.	got7fsn_ti	positive regulation of integrin complex activation													biological_process											owl:Class	
GO:0022815	biolink:NamedThing	obsolete large uncharged polar molecule transmembrane transporter activity	OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of a membrane to the other.	got7fsn_ti	large uncharged polar molecule transmembrane transporter activity			GO:0022857	This term was made obsolete because 'large uncharged polar molecule' is not a useful chemical grouping term.					True				molecular_function											owl:Class	
GO:1900685	biolink:NamedThing	positive regulation of fumonisin biosynthetic process	Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process.	got7fsn_ti	up regulation of fumonisin anabolism|up-regulation of fumonisin anabolism|activation of fumonisin anabolism|up regulation of fumonisin formation|upregulation of fumonisin formation|up-regulation of fumonisin biosynthesis|up-regulation of fumonisin synthesis|positive regulation of fumonisin anabolism|positive regulation of fumonisin synthesis|activation of fumonisin biosynthesis|activation of fumonisin synthesis|positive regulation of fumonisin biosynthesis|up regulation of fumonisin biosynthesis|up-regulation of fumonisin biosynthetic process|activation of fumonisin biosynthetic process|up regulation of fumonisin biosynthetic process|upregulation of fumonisin biosynthesis|upregulation of fumonisin biosynthetic process|up regulation of fumonisin synthesis|up-regulation of fumonisin formation|upregulation of fumonisin synthesis|positive regulation of fumonisin formation|upregulation of fumonisin anabolism|activation of fumonisin formation						di	2012-05-22T04:30:06Z						biological_process											owl:Class	
GO:0120225	biolink:NamedThing	coenzyme A binding	Binding to coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	got7fsn_ti	CoA binding						krc	2020-05-06T18:22:56Z						molecular_function											owl:Class	
GO:1902718	biolink:NamedThing	obsolete sequestering of copper ion	OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of copper ion.	got7fsn_ti	sequestering of copper ion				This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2014-02-24T16:08:53Z		True				biological_process											owl:Class	
GO:1903346	biolink:NamedThing	positive regulation of protein polyglycylation	Any process that activates or increases the frequency, rate or extent of protein polyglycylation.	got7fsn_ti	activation of protein polyglycylation|up regulation of protein polyglycylation|upregulation of protein polyglycylation|up-regulation of protein polyglycylation						sart	2014-08-19T09:32:24Z						biological_process											owl:Class	
GO:0002721	biolink:NamedThing	regulation of B cell cytokine production	Any process that modulates the frequency, rate, or extent of B cell cytokine production.	got7fsn_ti	regulation of B lymphocyte cytokine production|regulation of B-cell cytokine production|regulation of B-lymphocyte cytokine production													biological_process											owl:Class	
GO:0080184	biolink:NamedThing	response to phenylpropanoid	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin.	got7fsn_ti							dhl	2011-08-10T04:28:21Z						biological_process											owl:Class	
GO:0099032	biolink:NamedThing	anchored component of postsynaptic early endosome membrane	The component of the postsynaptic early endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0004189	biolink:NamedThing	obsolete tubulinyl-Tyr carboxypeptidase activity	OBSOLETE. Catalysis of the cleavage of the Glu-Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr.	got7fsn_ti	tyrosinotubulin carboxypeptidase activity|tubulinyltyrosine carboxypeptidase activity|carboxypeptidase-tubulin activity|tubulin-tyrosine carboxypeptidase activity|tubulin carboxypeptidase activity|tyrosyltubulin carboxypeptidase activity|tubulinyl-tyrosine carboxypeptidase activity|TTCPase activity|soluble carboxypeptidase activity|brain I carboxypeptidase activity|tubulinyl-Tyr carboxypeptidase activity			GO:0004181	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0033235	biolink:NamedThing	positive regulation of protein sumoylation	Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.	got7fsn_ti	positive regulation of sumoylation													biological_process											owl:Class	
GO:0061931	biolink:NamedThing	positive regulation of erythrocyte enucleation	Any process that increases the frequency, rate or extent of erythrocyte enucleation.	got7fsn_ti							dph	2017-09-05T12:57:33Z						biological_process											owl:Class	
GO:1904032	biolink:NamedThing	regulation of t-SNARE clustering	Any process that modulates the frequency, rate or extent of t-SNARE clustering.	got7fsn_ti							sl	2015-03-13T21:21:38Z						biological_process											owl:Class	
GO:0031403	biolink:NamedThing	lithium ion binding	Binding to a lithium ion (Li+).	got7fsn_ti	Li+ ion binding													molecular_function											owl:Class	
GO:0006484	biolink:NamedThing	obsolete protein cysteine-thiol oxidation	OBSOLETE. Oxidation of two cysteine sulfhydryl groups (thiols) in one protein by a disulfide bond in a second protein to form a disulfide bond in the first protein and two reduced sulfhydryls in the second. The oxidized cysteines linked by a disulfide bond is known as cystine.	got7fsn_ti	protein cysteine-thiol oxidation				This term was made obsolete because it represents a single activity.	GO:0003756				True				biological_process											owl:Class	
OBO:OBA_0000105	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045870	biolink:NamedThing	positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	Any process that activates or increases the frequency, rate or extent of retroviral genome replication.	got7fsn_ti	up regulation of retroviral genome replication|stimulation of retroviral genome replication|up-regulation of retroviral genome replication|activation of retroviral genome replication|positive regulation of retroviral genome replication|upregulation of retroviral genome replication													biological_process											owl:Class	
GO:0031458	biolink:NamedThing	ABC-type betaine transporter activity	Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in).	got7fsn_ti	ABC-type betaine transmembrane transporter activity|betaine ABC transporter|ATPase-coupled betaine transporter activity|betaine-transporting ATPase activity|ATP-dependent betaine transporter activity													molecular_function											owl:Class	
GO:0046440	biolink:NamedThing	L-lysine metabolic process	The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid.	got7fsn_ti	L-lysine metabolism													biological_process											owl:Class	
GO:1904426	biolink:NamedThing	positive regulation of GTP binding	Any process that activates or increases the frequency, rate or extent of GTP binding.	got7fsn_ti	activation of GTP binding|up regulation of GTP binding|up-regulation of GTP binding|upregulation of GTP binding						sl	2015-07-02T20:35:07Z						biological_process											owl:Class	
GO:1905954	biolink:NamedThing	positive regulation of lipid localization	Any process that activates or increases the frequency, rate or extent of lipid localization.	got7fsn_ti	up-regulation of lipid localization|upregulation of lipid localisation|up regulation of lipid localization|up-regulation of lipid localisation|activation of lipid localization|up regulation of lipid localisation|upregulation of lipid localization|positive regulation of lipid localisation|activation of lipid localisation						rz	2017-02-21T12:12:49Z						biological_process											owl:Class	
GO:0023011	biolink:NamedThing	obsolete positive regulation of initiation of T cell receptor signaling	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of the initiation of T cell receptor signaling.	got7fsn_ti	positive regulation of initiation of T cell receptor signalling|positive regulation of initiation of T cell receptor signaling				This term was made obsolete because the meaning of the term is ambiguous.	GO:0050862		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0097067	biolink:NamedThing	cellular response to thyroid hormone stimulus	A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.	got7fsn_ti							pr	2011-06-14T05:02:47Z						biological_process											owl:Class	
GO:1904199	biolink:NamedThing	positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization	Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.	got7fsn_ti	activation of regulation of vascular smooth muscle cell membrane depolarization|up-regulation of regulation of vascular smooth muscle cell membrane depolarization|positive regulation of regulation of vascular smooth muscle cell membrane depolarization|up regulation of regulation of vascular smooth muscle cell membrane depolarization|upregulation of regulation of vascular smooth muscle cell membrane depolarization						sl	2015-05-07T17:16:50Z						biological_process											owl:Class	
GO:0033700	biolink:NamedThing	phospholipid efflux	The directed movement of a phospholipid out of a cell or organelle.	got7fsn_ti	phospholipid export													biological_process											owl:Class	
GO:1901585	biolink:NamedThing	regulation of acid-sensing ion channel activity	Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity.	got7fsn_ti	regulation of ASIC activity						jl	2012-11-07T13:37:24Z						biological_process											owl:Class	
GO:1903798	biolink:NamedThing	regulation of production of miRNAs involved in gene silencing by miRNA	Any process that modulates the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.	got7fsn_ti	regulation of microRNA biosynthesis|regulation of miRNA biogenesis|regulation of gene silencing by miRNA, production of miRNAs|regulation of miRNA-mediated gene silencing, production of miRNAs|regulation of production of microRNAs involved in gene silencing by microRNA|regulation of microRNA-mediated gene silencing, production of microRNAs|regulation of microRNA metabolism|regulation of microRNA processing|regulation of microRNA biogenesis|regulation of miRNA processing|regulation of microRNA biosynthetic process|regulation of microRNA metabolic process						rph	2015-01-15T13:58:12Z						biological_process											owl:Class	
GO:1902338	biolink:NamedThing	negative regulation of apoptotic process involved in morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.	got7fsn_ti	inhibition of morphogenetic apoptosis|inhibition of apoptosis involved in morphogenesis|down regulation of apoptosis involved in development|down regulation of apoptotic process involved in morphogenesis|down regulation of morphogenetic apoptosis|down regulation of apoptosis involved in morphogenesis|downregulation of apoptosis involved in morphogenesis|negative regulation of morphogenetic apoptosis|downregulation of apoptotic process involved in morphogenesis|down-regulation of apoptosis involved in development|down-regulation of apoptotic process involved in morphogenesis|down-regulation of morphogenetic apoptosis|negative regulation of apoptosis involved in development|inhibition of apoptosis involved in development|downregulation of apoptosis involved in development|inhibition of apoptotic process involved in morphogenesis|down-regulation of apoptosis involved in morphogenesis|downregulation of morphogenetic apoptosis|negative regulation of apoptosis involved in morphogenesis						sart	2013-07-29T15:03:25Z						biological_process											owl:Class	
GO:1905652	biolink:NamedThing	negative regulation of artery morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis.	got7fsn_ti	downregulation of artery morphogenesis|down regulation of arteriogenesis|down-regulation of arterial morphogenesis|down-regulation of artery morphogenesis|negative regulation of arteriogenesis|downregulation of arterial morphogenesis|inhibition of arteriogenesis|down-regulation of arteriogenesis|negative regulation of arterial morphogenesis|downregulation of arteriogenesis|inhibition of artery morphogenesis|inhibition of arterial morphogenesis|down regulation of arterial morphogenesis|down regulation of artery morphogenesis						rph	2016-11-09T12:19:53Z						biological_process											owl:Class	
GO:0003776	biolink:NamedThing	obsolete muscle motor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	muscle motor activity			GO:0000146	This term was made obsolete because it includes anatomy information.	GO:0043292|GO:0006936				True				molecular_function											owl:Class	
GO:1903814	biolink:NamedThing	regulation of collecting lymphatic vessel constriction	Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction.	got7fsn_ti	regulation of lymphatic vessel myogenic constriction						sl	2015-01-16T17:01:49Z						biological_process											owl:Class	
GO:1902935	biolink:NamedThing	protein localization to septin ring	A process in which a protein is transported to, or maintained in, a location within a septin ring.	got7fsn_ti	protein localisation in septin ring|protein localisation to septin ring|protein localization in septin ring						mah	2014-04-25T13:08:17Z						biological_process											owl:Class	
GO:0032662	biolink:NamedThing	regulation of interleukin-19 production	Any process that modulates the frequency, rate, or extent of interleukin-19 production.	got7fsn_ti	regulation of IL-19 production|regulation of interleukin-19 biosynthetic process										GO:0045384			biological_process											owl:Class	
GO:1901604	biolink:NamedThing	dethiobiotin transmembrane transporter activity	Enables the transfer of dethiobiotin from one side of a membrane to the other.	got7fsn_ti							al	2012-11-08T14:42:53Z						molecular_function											owl:Class	
GO:2000715	biolink:NamedThing	regulation of maintenance of mitotic sister chromatid cohesion, arms	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.	got7fsn_ti	regulation of maintenance of mitotic sister chromatin cohesion along arms|regulation of maintenance of sister chromatin cohesion along arms at mitosis						mah	2011-06-03T10:38:29Z						biological_process											owl:Class	
GO:1905050	biolink:NamedThing	positive regulation of metallopeptidase activity	Any process that activates or increases the frequency, rate or extent of metallopeptidase activity.	got7fsn_ti	up-regulation of metalloproteinase activity|up-regulation of metallopeptidase activity|positive regulation of metalloproteinase activity|up regulation of metallopeptidase activity|up regulation of metalloprotease activity|activation of metalloproteinase activity|activation of metallopeptidase activity|activation of metalloprotease activity|upregulation of metalloprotease activity|positive regulation of metalloprotease activity|up regulation of metalloproteinase activity|up-regulation of metalloprotease activity|upregulation of metalloproteinase activity|upregulation of metallopeptidase activity						mm2	2016-03-15T16:44:46Z						biological_process											owl:Class	
CHEBI:60377	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902766	biolink:NamedThing	skeletal muscle satellite cell migration	The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells.	got7fsn_ti							mr	2014-03-10T15:20:28Z						biological_process											owl:Class	
GO:1901783	biolink:NamedThing	p-cumate biosynthetic process	The chemical reactions and pathways resulting in the formation of p-cumate.	got7fsn_ti	p-cumate biosynthesis|p-cumate anabolism|p-cumate synthesis|p-cumate formation						yaf	2013-01-16T10:40:36Z						biological_process											owl:Class	
GO:0140227	biolink:NamedThing	serotonin-gated cation-selective signaling pathway	A series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti	serotonin-gated cation-selective signalling pathway|5-hydroxytryptamine-gated cation-selective signaling pathway|5-HT-gated cation-selective signalling pathway|5-hydroxytryptamine-gated cation-selective signalling pathway|5-HT-gated cation-selective signaling pathway						pg	2018-06-02T13:34:51Z						biological_process											owl:Class	
GO:0110138	biolink:NamedThing	positive regulation of imaginal disc-derived leg joint morphogenesis	Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.	got7fsn_ti							kmv	2019-02-12T15:37:05Z						biological_process											owl:Class	
GO:0009587	biolink:NamedThing	obsolete phototrophin mediated phototransduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	phototrophin mediated phototransduction			GO:0007602						True				biological_process											owl:Class	
GO:0071867	biolink:NamedThing	response to monoamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.	got7fsn_ti	response to monoamine stimulus						mah	2010-09-13T02:36:37Z						biological_process											owl:Class	
GO:0000284	biolink:NamedThing	obsolete shmoo orientation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	shmoo orientation			GO:0000753	This term was made obsolete because it is an organism specific term. The entire branch of the ontology was reorganized to be more generally applicable.					True				biological_process											owl:Class	
GO:1902954	biolink:NamedThing	regulation of early endosome to recycling endosome transport	Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport.	got7fsn_ti							sjp	2014-05-02T09:06:23Z						biological_process											owl:Class	
GO:0002925	biolink:NamedThing	positive regulation of humoral immune response mediated by circulating immunoglobulin	Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.	got7fsn_ti	stimulation of humoral immune response mediated by circulating immunoglobulin|up regulation of humoral immune response mediated by circulating immunoglobulin|up-regulation of humoral immune response mediated by circulating immunoglobulin|upregulation of humoral immune response mediated by circulating immunoglobulin|activation of humoral immune response mediated by circulating immunoglobulin													biological_process											owl:Class	
PR:000008875	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000607	biolink:NamedThing	negative regulation of cell proliferation involved in mesonephros development	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development.	got7fsn_ti							yaf	2011-04-18T08:42:23Z						biological_process											owl:Class	
GO:1903469	biolink:NamedThing	removal of RNA primer involved in mitotic DNA replication	Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication.	got7fsn_ti	Okazaki initiator RNA removal involved in mitotic cell cycle DNA replication|Okazaki initiator RNA removal involved in mitotic nuclear cell cycle DNA replication|Okazaki initiator RNA removal involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication involved in S phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in DNA replication during S phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in mitotic nuclear cell cycle DNA replication|DNA replication, removal of RNA primer involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication during S phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in DNA replication involved in S-phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in nuclear cell cycle DNA replication involved in mitotic cell cycle						vw	2014-09-23T13:42:24Z						biological_process											owl:Class	
GO:1905925	biolink:NamedThing	obsolete negative regulation of invadopodium assembly	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium assembly.	got7fsn_ti	down-regulation of invadopodium formation|negative regulation of invadopodium formation|down-regulation of invadopodium assembly|down regulation of invadopodium formation|downregulation of invadopodium assembly|down regulation of invadopodium assembly|downregulation of invadopodium formation|inhibition of invadopodium formation|inhibition of invadopodium assembly				This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:38:39Z		True				biological_process											owl:Class	
GO:0070862	biolink:NamedThing	negative regulation of protein exit from endoplasmic reticulum	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.	got7fsn_ti	down regulation of protein exit from endoplasmic reticulum|negative regulation of protein export from endoplasmic reticulum|negative regulation of protein export from ER|inhibition of protein exit from endoplasmic reticulum|downregulation of protein exit from endoplasmic reticulum|down-regulation of protein exit from endoplasmic reticulum|negative regulation of protein exit from ER						mah	2009-08-17T03:45:56Z						biological_process											owl:Class	
GO:1904589	biolink:NamedThing	regulation of protein import	Any process that modulates the frequency, rate or extent of protein import.	got7fsn_ti	regulation of protein uptake						sl	2015-08-20T21:26:30Z						biological_process											owl:Class	
GO:0010592	biolink:NamedThing	positive regulation of lamellipodium assembly	Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.	got7fsn_ti	positive regulation of lamellipodium biogenesis													biological_process											owl:Class	
GO:0075040	biolink:NamedThing	regulation of establishment of turgor in appressorium	Any process modulates the frequency, rate or extent of turgor formation in the symbiont appressorium.	got7fsn_ti	regulation of turgor formation in appressorium													biological_process											owl:Class	
GO:1901729	biolink:NamedThing	monensin A catabolic process	The chemical reactions and pathways resulting in the breakdown of monensin A.	got7fsn_ti	monensin A catabolism|monensin degradation|monensin catabolism|monensin A degradation|monensin A breakdown|monensin breakdown						yaf	2013-01-09T11:55:49Z						biological_process											owl:Class	
GO:0009264	biolink:NamedThing	deoxyribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	deoxyribonucleotide breakdown|deoxyribonucleotide degradation|deoxyribonucleotide catabolism													biological_process											owl:Class	
GO:0035391	biolink:NamedThing	obsolete maintenance of chromatin silencing at silent mating-type cassette	OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19301			This term was obsoleted because it represents a phenotype.		bf	2010-03-22T10:25:14Z		True				biological_process											owl:Class	
GO:0030816	biolink:NamedThing	obsolete positive regulation of cAMP metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	positive regulation of 3',5'-cAMP metabolism|positive regulation of cyclic AMP metabolic process|positive regulation of cyclic AMP metabolism|positive regulation of adenosine 3',5'-cyclophosphate metabolism|stimulation of cAMP metabolic process|positive regulation of 3',5' cAMP metabolism|up regulation of cAMP metabolic process|positive regulation of adenosine 3',5'-cyclophosphate metabolic process|positive regulation of cAMP metabolism|upregulation of cAMP metabolic process|positive regulation of 3',5' cAMP metabolic process|positive regulation of 3',5'-cAMP metabolic process|up-regulation of cAMP metabolic process|activation of cAMP metabolic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0006734	biolink:NamedThing	NADH metabolic process	The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.	got7fsn_ti	reduced NAD metabolism|reduced NAD metabolic process|NAD (reduced) metabolic process|reduced nicotinamide adenine dinucleotide metabolism|reduced nicotinamide adenine dinucleotide metabolic process|NAD (reduced) metabolism|NADH metabolism													biological_process											owl:Class	
GO:0032929	biolink:NamedThing	negative regulation of superoxide anion generation	Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.	got7fsn_ti	inhibition of superoxide release|downregulation of superoxide release|negative regulation of superoxide release|down-regulation of superoxide release|down regulation of superoxide release													biological_process											owl:Class	
GO:0005187	biolink:NamedThing	obsolete storage protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	storage protein			GO:0045735	This term was made obsolete because it describes a cellular location rather than a function.					True				molecular_function											owl:Class	
GO:0090211	biolink:NamedThing	positive regulation of establishment of blood-brain barrier	Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.	got7fsn_ti	positive regulation of establishment of BBB						tb	2009-12-23T12:15:53Z						biological_process											owl:Class	
GO:0005016	biolink:NamedThing	obsolete neurotrophin TRKC receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	neurotrophin TRKC receptor activity				This term was made obsolete because it represents a gene product.	GO:0007165|GO:0004714|GO:0043121				True				molecular_function											owl:Class	
GO:0100056	biolink:NamedThing	obsolete negative regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylserine biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1904578	biolink:NamedThing	response to thapsigargin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus.	got7fsn_ti							sl	2015-08-19T18:06:22Z						biological_process											owl:Class	
GO:0043745	biolink:NamedThing	obsolete N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity	OBSOLETE. Catalysis of the reaction: N2-acetyl-L-aminoadipyl-delta-phosphate + NADPH + H+ = N2-acetyl-L-aminoadipate semialdehyde + NADP+ + orthophosphate.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18908			This term was obsoleted because there is no evidence that it exists.					True				molecular_function											owl:Class	
GO:0043378	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta T cell differentiation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation.	got7fsn_ti	upregulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha beta T-lymphocyte differentiation|up regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive T-lymphocyte differentiation|positive regulation of CD8-positive T lymphocyte differentiation|positive regulation of CD8-positive, alpha beta T-cell differentiation|positive regulation of CD8-positive T-cell differentiation|activation of CD8-positive, alpha-beta T cell differentiation|stimulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha beta T lymphocyte differentiation|up-regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha-beta T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0009258	biolink:NamedThing	10-formyltetrahydrofolate catabolic process	The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.	got7fsn_ti	10-formyl-THF catabolic process|10-formyl-THF catabolism|10-formyltetrahydrofolate breakdown|10-formyltetrahydrofolate catabolism|10-formyltetrahydrofolate degradation													biological_process											owl:Class	
GO:0034617	biolink:NamedThing	tetrahydrobiopterin binding	Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.	got7fsn_ti	BH4 binding|H4biopterin binding|sapropterin binding													molecular_function											owl:Class	
GO:1901265	biolink:NamedThing	nucleoside phosphate binding	Binding to nucleoside phosphate.	got7fsn_ti							bf	2012-08-17T12:59:58Z						molecular_function											owl:Class	
GO:1901048	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription, that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.	got7fsn_ti	TGFbeta receptor signaling pathway of regulation of body growth|TGFbeta receptor signalling pathway of regulation of body growth|TGFbeta receptor signalling pathway of regulation of body size|TGFbeta receptor signaling pathway of regulation of body size|transforming growth factor beta receptor signalling pathway of regulation of body growth|TGFbeta receptor signaling pathway of regulation of multicellular organism growth|TGF-beta receptor signalling pathway of regulation of body size|transforming growth factor beta receptor signalling pathway of regulation of body size|transforming growth factor beta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of body growth|transforming growth factor beta receptor signaling pathway of regulation of body growth|TGF-beta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of body size|TGFbeta receptor signalling pathway of regulation of multicellular organism growth|TGF-beta receptor signalling pathway of regulation of body growth|transforming growth factor beta receptor signaling pathway of regulation of multicellular organism growth|TGF-beta receptor signaling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signaling pathway of regulation of body size						kmv	2012-06-27T07:37:22Z						biological_process											owl:Class	
CHEBI:35236	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034184	biolink:NamedThing	positive regulation of maintenance of mitotic sister chromatid cohesion	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0005928	biolink:NamedThing	obsolete apical hemi-adherens junction	OBSOLETE. A cell-substrate adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle.	got7fsn_ti	apical cell-substrate adherens junction|apical dense plaque				The reason for obsoletion is that this term has not been used for GO annotation at all since 2001 when it was created, it has no children, it is not a part of any subset/slim.					True				cellular_component											owl:Class	
GO:1900474	biolink:NamedThing	obsolete negative regulation of mating type switching by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T08:33:18Z		True				biological_process											owl:Class	
GO:1903753	biolink:NamedThing	negative regulation of p38MAPK cascade	Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.	got7fsn_ti	downregulation of p38 cascade|inhibition of p38MAPK cascade|down regulation of p38 MAPK cascade|down regulation of p38 cascade|inhibition of p38 MAPK cascade|down-regulation of p38 MAPK cascade|down-regulation of p38 cascade|downregulation of p38 MAPK cascade|down regulation of p38MAPK cascade|negative regulation of p38 cascade|down-regulation of p38MAPK cascade|downregulation of p38MAPK cascade|negative regulation of p38 MAPK cascade|inhibition of p38 cascade						krc	2014-12-12T23:09:26Z						biological_process											owl:Class	
GO:0060774	biolink:NamedThing	auxin mediated signaling pathway involved in phyllotactic patterning	The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.	got7fsn_ti	auxin mediated signalling pathway involved in phyllotactic patterning						dph	2009-07-25T06:31:13Z						biological_process											owl:Class	
GO:0090356	biolink:NamedThing	negative regulation of auxin metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.	got7fsn_ti	negative regulation of auxin metabolism						tb	2010-06-29T01:51:18Z						biological_process											owl:Class	
GO:1900841	biolink:NamedThing	negative regulation of helvolic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process.	got7fsn_ti	down regulation of helvolic acid biosynthetic process|down-regulation of helvolic acid biosynthetic process|downregulation of helvolic acid biosynthetic process						di	2012-06-07T09:38:57Z						biological_process											owl:Class	
GO:0150098	biolink:NamedThing	glial cell-neuron signaling	Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signalling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum.	got7fsn_ti	glia-neurone signalling|glia-neurone signaling|glial cell-neurone singaling|glial cell-neurone signalling|glia-neuron signaling|glial cell- neuron signalling|glia-neuron signalling						bc	2018-12-17T12:28:09Z						biological_process											owl:Class	
GO:1900223	biolink:NamedThing	positive regulation of amyloid-beta clearance	Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance.	got7fsn_ti	positive regulation of beta-amyloid clearance|activation of beta-amyloid clearance|up-regulation of beta-amyloid clearance|upregulation of beta-amyloid clearance|up regulation of beta-amyloid clearance						vk	2012-03-22T01:29:50Z						biological_process											owl:Class	
GO:0080088	biolink:NamedThing	spermidine hydroxycinnamate conjugate biosynthetic process	The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates.	got7fsn_ti							dhl	2009-04-22T03:24:03Z						biological_process											owl:Class	
GO:1901728	biolink:NamedThing	monensin A metabolic process	The chemical reactions and pathways involving monensin A.	got7fsn_ti	monensin metabolism|monensin A metabolism						yaf	2013-01-09T11:55:45Z						biological_process											owl:Class	
GO:0097247	biolink:NamedThing	epigallocatechin 3-gallate binding	Binding to epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin.	got7fsn_ti	catechin gallate binding|EGCG binding						pr	2012-02-17T03:55:05Z						molecular_function											owl:Class	
GO:0033312	biolink:NamedThing	chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a	The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a.	got7fsn_ti	chlorophyll a synthesis via geranylgeranyl-chlorophyll a|chlorophyll a anabolism via geranylgeranyl-chlorophyll a|chlorophyll a biosynthesis via geranylgeranyl-chlorophyll a|chlorophyll a formation via geranylgeranyl-chlorophyll a											MetaCyc:PWY-5064		biological_process											owl:Class	
GO:0045724	biolink:NamedThing	positive regulation of cilium assembly	Any process that activates or increases the frequency, rate or extent of the formation of a cilium.	got7fsn_ti	stimulation of cilium assembly|positive regulation of flagellum assembly|upregulation of cilium assembly|up-regulation of cilium assembly|positive regulation of flagellum biogenesis|activation of cilium assembly|up regulation of cilium assembly													biological_process											owl:Class	
GO:1902049	biolink:NamedThing	neosartoricin catabolic process	The chemical reactions and pathways resulting in the breakdown of neosartoricin.	got7fsn_ti	neosartoricin breakdown|neosartoricin catabolism|neosartoricin degradation						di	2013-04-08T20:31:06Z						biological_process											owl:Class	
GO:0046448	biolink:NamedThing	tropane alkaloid metabolic process	The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.	got7fsn_ti	tropane alkaloid metabolism													biological_process											owl:Class	
GO:1900307	biolink:NamedThing	negative regulation of maltoheptaose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport.	got7fsn_ti	down-regulation of maltoheptaose transport|downregulation of maltoheptaose transport|down regulation of maltoheptaose transport|inhibition of maltoheptaose transport						tt	2012-04-05T07:58:27Z						biological_process											owl:Class	
GO:0060766	biolink:NamedThing	negative regulation of androgen receptor signaling pathway	Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.	got7fsn_ti	negative regulation of androgen receptor signalling pathway						dph	2009-07-06T11:09:36Z						biological_process											owl:Class	
GO:1902355	biolink:NamedThing	endothelial tube lumen extension involved in blood vessel lumen ensheathment	Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment.	got7fsn_ti							pr	2013-08-14T10:22:09Z						biological_process											owl:Class	
GO:1900197	biolink:NamedThing	negative regulation of penicillin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process.	got7fsn_ti	inhibition of penicillin biosynthesis|downregulation of penicillin biosynthesis|down regulation of penicillin formation|negative regulation of penicillin formation|negative regulation of penicillin biosynthesis|down regulation of penicillin biosynthetic process|down-regulation of penicillin anabolism|down-regulation of penicillin biosynthesis|inhibition of penicillin anabolism|down-regulation of penicillin biosynthetic process|downregulation of penicillin biosynthetic process|inhibition of penicillin synthesis|down regulation of penicillin biosynthesis|negative regulation of penicillin synthesis|negative regulation of penicillin anabolism|downregulation of penicillin synthesis|down-regulation of penicillin synthesis|down regulation of penicillin synthesis|downregulation of penicillin formation|inhibition of penicillin biosynthetic process|downregulation of penicillin anabolism|down regulation of penicillin anabolism|inhibition of penicillin formation|down-regulation of penicillin formation						di	2012-03-20T03:56:43Z						biological_process											owl:Class	
GO:2000646	biolink:NamedThing	positive regulation of receptor catabolic process	Any process that activates or increases the frequency, rate or extent of receptor catabolic process.	got7fsn_ti	positive regulation of receptor degradation|positive regulation of receptor breakdown|positive regulation of receptor catabolism						vk	2011-04-21T11:20:25Z						biological_process											owl:Class	
GO:0031921	biolink:NamedThing	pyridoxal phosphate transport	The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.	got7fsn_ti														biological_process											owl:Class	
GO:0051436	biolink:NamedThing	obsolete negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.	got7fsn_ti	down-regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic anaphase promoting complex inhibitor|downregulation of ubiquitin ligase activity during mitotic cell cycle|anaphase promoting complex inhibition during mitotic cell cycle|APC inhibition during mitotic cell cycle|mitotic APC inhibitor|mitotic APC inhibition|anaphase-promoting complex inhibition during mitotic cell cycle|mitotic anaphase promoting complex inhibition|mitotic anaphase-promoting complex inhibition|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle|negative regulation of ubiquitin ligase activity during mitotic cell cycle|down regulation of ubiquitin ligase activity during mitotic cell cycle|inhibition of ubiquitin ligase activity during mitotic cell cycle|mitotic ubiquitin ligase inhibitor|mitotic SCF complex inhibitor|mitotic anaphase-promoting complex inhibitor	https://github.com/geneontology/go-ontology/issues/15196			This term was obsoleted because it should be captured as a GO-CAM model.					True				biological_process											owl:Class	
GO:1901867	biolink:NamedThing	ecgonine methyl ester metabolic process	The chemical reactions and pathways involving ecgonine methyl ester.	got7fsn_ti	ecgonine methyl ester metabolism						ms	2013-02-04T11:58:14Z						biological_process											owl:Class	
GO:1904184	biolink:NamedThing	positive regulation of pyruvate dehydrogenase activity	Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity.	got7fsn_ti	positive regulation of pyruvic acid dehydrogenase activity|up-regulation of pyruvate dehydrogenase activity|up-regulation of pyruvic dehydrogenase activity|up-regulation of pyruvic acid dehydrogenase activity|up regulation of pyruvate dehydrogenase activity|up regulation of pyruvic acid dehydrogenase activity|upregulation of pyruvic acid dehydrogenase activity|upregulation of pyruvic dehydrogenase activity|positive regulation of pyruvic dehydrogenase activity|activation of pyruvate dehydrogenase activity|activation of pyruvic dehydrogenase activity|activation of pyruvic acid dehydrogenase activity|up regulation of pyruvic dehydrogenase activity|upregulation of pyruvate dehydrogenase activity						dph	2015-05-05T14:17:39Z						biological_process											owl:Class	
GO:2000009	biolink:NamedThing	negative regulation of protein localization to cell surface	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface.	got7fsn_ti	negative regulation of protein localization at cell surface|negative regulation of protein localisation at cell surface						jl	2010-08-04T01:43:52Z						biological_process											owl:Class	
GO:0005037	biolink:NamedThing	obsolete death receptor adaptor protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	death receptor adaptor protein activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005515|GO:0005123				True				molecular_function											owl:Class	
GO:0007577	biolink:NamedThing	obsolete autophagic death (sensu Saccharomyces)	OBSOLETE. This process is a type of programmed cell death pathway similar to apoptosis and necrosis observed in multicellular organisms. It is characterized by cellular enlargement (necrosis) and presence of many autophagic bodies along with degradation of cellular components (nucleus, Golgi, ER), protein, DNA and RNA.	got7fsn_ti	autophagic death (sensu Saccharomyces)				This term was made obsolete because a more correct term has been created.	GO:0048102				True				biological_process											owl:Class	
GO:1902472	biolink:NamedThing	regulation of mitotic cytokinesis, site selection	Any process that modulates the frequency, rate or extent of mitotic cytokinesis, site selection.	got7fsn_ti							mah	2013-10-24T14:20:12Z						biological_process											owl:Class	
GO:1905051	biolink:NamedThing	regulation of base-excision repair	Any process that modulates the frequency, rate or extent of base-excision repair.	got7fsn_ti	regulation of BER						ah	2016-03-16T10:52:00Z						biological_process											owl:Class	
GO:0006117	biolink:NamedThing	acetaldehyde metabolic process	The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.	got7fsn_ti	ethanal metabolism|ethanal metabolic process|acetaldehyde metabolism													biological_process											owl:Class	
GO:0086102	biolink:NamedThing	adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	A G protein-coupled acetylcholine receptor signaling pathway that contributes to an decrease in frequency or rate of heart contraction through inhibition of adenylate cyclase (AC) activity. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gi/o protein. Gi/o inhibits adenylate cyclase to decrease cyclic-AMP (cAMP) levels. Since cAMP binds directly to F-channels to allow an inward flow of sodium (funny current, If current), a reduction in cAMP reduces the funny current to bring about membrane hyperpolarization and a decrease in heart rate.	got7fsn_ti	AC-inhibiting muscarinic receptor signaling pathway involved in negative regulation of heart rate|adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of funny current|G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate via inhibition of adenylate cyclase activity|Gi-coupled G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of If channel						bf							biological_process											owl:Class	
GO:0001813	biolink:NamedThing	regulation of antibody-dependent cellular cytotoxicity	Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity.	got7fsn_ti	regulation of antibody-dependent cell death|regulation of antibody-dependent cell killing|regulation of antibody dependent cell killing|regulation of antibody dependent cell death													biological_process											owl:Class	
GO:0046048	biolink:NamedThing	UDP metabolic process	The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate.	got7fsn_ti	UDP metabolism													biological_process											owl:Class	
GO:0070487	biolink:NamedThing	monocyte aggregation	The adhesion of one monocyte to one or more other monocytes via adhesion molecules.	got7fsn_ti	mononuclear phagocyte aggregation													biological_process											owl:Class	
GO:0051196	biolink:NamedThing	obsolete regulation of coenzyme metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.	got7fsn_ti	regulation of coenzyme metabolism|regulation of coenzyme and prosthetic group metabolism|regulation of coenzyme and prosthetic group metabolic process				1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True				biological_process											owl:Class	
GO:1900292	biolink:NamedThing	negative regulation of galactotriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport.	got7fsn_ti	downregulation of galactotriose transport|down regulation of galactotriose transport|inhibition of galactotriose transport|down-regulation of galactotriose transport						tt	2012-04-05T07:26:08Z						biological_process											owl:Class	
GO:1900102	biolink:NamedThing	negative regulation of endoplasmic reticulum unfolded protein response	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response.	got7fsn_ti	inhibition of endoplasmic reticulum unfolded protein response|inhibition of SREBP-mediated signalling pathway|downregulation of ER unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response|downregulation of SREBP-mediated signalling pathway|down regulation of erUPR|down regulation of SREBP-mediated signalling pathway|down-regulation of ER unfolded protein response|negative regulation of SREBP-mediated signalling pathway|negative regulation of erUPR|downregulation of erUPR|down regulation of endoplasmic reticulum unfolded protein response|down regulation of ER unfolded protein response|down-regulation of endoplasmic reticulum unfolded protein response|inhibition of ER unfolded protein response|down-regulation of erUPR|inhibition of erUPR|negative regulation of ER unfolded protein response|down-regulation of SREBP-mediated signalling pathway						ppm	2012-02-15T11:15:31Z						biological_process											owl:Class	
GO:1902357	biolink:NamedThing	2-isopropylmalate(2-) transmembrane transport	The process in which 2-isopropylmalate(2-) is transported across a membrane.	got7fsn_ti							dph	2013-08-14T14:43:49Z						biological_process											owl:Class	
GO:0051902	biolink:NamedThing	negative regulation of mitochondrial depolarization	Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.	got7fsn_ti	inhibition of mitochondrial depolarization|downregulation of mitochondrial depolarization|down regulation of mitochondrial depolarization|down-regulation of mitochondrial depolarization													biological_process											owl:Class	
GO:0000206	biolink:NamedThing	obsolete inactivation of MAPK during sporulation (sensu Saccharomyces)	OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	got7fsn_ti	inactivation of MAPK during sporulation (sensu Saccharomyces)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:2000805	biolink:NamedThing	negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.	got7fsn_ti	negative regulation of transcription termination from Pol II promoter, poly(A) coupled|negative regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|negative regulation of termination of RNA polymerase II transcription, polyadenylation-coupled						pr	2011-07-04T08:41:34Z						biological_process											owl:Class	
GO:0006755	biolink:NamedThing	obsolete carbamoyl phosphate-ADP transphosphorylation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	carbamoyl phosphate-ADP transphosphorylation				This term was made obsolete because, according to PUMA2, this "pathway" is a single reaction, corresponding to 'carbamate kinase activity ; GO:0008804' (EC:2.7.2.2).					True				biological_process											owl:Class	
GO:0005645	biolink:NamedThing	obsolete RAN-binding protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	RAN-binding protein			GO:0031267	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:1900015	biolink:NamedThing	regulation of cytokine production involved in inflammatory response	Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.	got7fsn_ti	regulation of cytokine production involved in acute inflammatory response						rph	2012-01-11T09:34:27Z						biological_process											owl:Class	
PR:000008476	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032763	biolink:NamedThing	regulation of mast cell cytokine production	Any process that modulates the frequency, rate, or extent of mast cell cytokine production.	got7fsn_ti														biological_process											owl:Class	
GO:0019495	biolink:NamedThing	proline catabolic process to 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate.	got7fsn_ti	proline degradation to 2-oxoglutarate|proline catabolic process to alpha-oxoglutarate|proline catabolism to alpha-ketoglutarate|proline catabolic process to alpha-ketoglutarate|proline breakdown to 2-oxoglutarate|proline catabolism to 2-ketoglutarate|proline catabolism to alpha-oxoglutarate|proline catabolic process to 2-ketoglutarate													biological_process											owl:Class	
GO:0075223	biolink:NamedThing	regulation of sporangium germination	Any process that modulates the frequency, rate or extent of sporangium germination.	got7fsn_ti	modulation of sporangium germination on or near host|modulation of sporangium germination													biological_process											owl:Class	
GO:1901693	biolink:NamedThing	negative regulation of compound eye retinal cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.	got7fsn_ti	down regulation of compound eye retinal cell apoptotic process|inhibition of compound eye retinal cell apoptotic process|downregulation of compound eye retinal cell apoptotic process|down-regulation of compound eye retinal cell apoptotic process						pr	2012-12-12T10:28:40Z						biological_process											owl:Class	
GO:1904749	biolink:NamedThing	regulation of protein localization to nucleolus	Any process that modulates the frequency, rate or extent of protein localization to nucleolus.	got7fsn_ti	regulation of protein localization in nucleolus|regulation of protein localisation to nucleolus|regulation of protein localisation in nucleolus						nc	2015-10-19T15:16:17Z						biological_process											owl:Class	
GO:2000259	biolink:NamedThing	positive regulation of protein activation cascade	Any process that activates or increases the frequency, rate or extent of protein activation cascade.	got7fsn_ti	positive regulation of protein activation pathway|positive regulation of protein activitory cascade						mah	2010-11-23T11:33:55Z						biological_process											owl:Class	
GO:1903881	biolink:NamedThing	regulation of interleukin-17-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.	got7fsn_ti	regulation of IL-17-mediated signalling pathway|regulation of IL-17-mediated signaling pathway|regulation of interleukin-17-mediated signalling pathway						krc	2015-02-06T16:26:38Z						biological_process											owl:Class	
GO:0033496	biolink:NamedThing	sinapate metabolic process	The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.	got7fsn_ti	sinapate metabolism													biological_process											owl:Class	
GO:0061013	biolink:NamedThing	regulation of mRNA catabolic process	Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.	got7fsn_ti	regulation of mRNA decay						dph	2010-01-29T01:48:10Z						biological_process											owl:Class	
GO:1900238	biolink:NamedThing	regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway.	got7fsn_ti	regulation of metanephric mesenchyme chemotaxis by platelet-derived growth factor receptor-beta signaling pathway|regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway						yaf	2012-03-27T03:33:56Z						biological_process											owl:Class	
GO:1902663	biolink:NamedThing	negative regulation of peptidyl-L-cysteine S-palmitoylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.	got7fsn_ti	downregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|downregulation of peptidyl-cysteine S-palmitoylation|inhibition of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down-regulation of peptidyl-cysteine S-palmitoylation|inhibition of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down regulation of peptidyl-cysteine S-palmitoylation|inhibition of peptidyl-L-cysteine S-palmitoylation|down-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|inhibition of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|inhibition of peptidyl-cysteine S-palmitoylation|negative regulation of peptidyl-cysteine S-palmitoylation|downregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down-regulation of peptidyl-L-cysteine S-palmitoylation|downregulation of peptidyl-L-cysteine S-palmitoylation|negative regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down regulation of peptidyl-L-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|inhibition of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine						mm2	2014-01-29T11:33:19Z						biological_process											owl:Class	
GO:1902180	biolink:NamedThing	verruculogen catabolic process	The chemical reactions and pathways resulting in the breakdown of verruculogen.	got7fsn_ti	verruculogen degradation|verruculogen catabolism|verruculogen breakdown						di	2013-05-30T17:44:30Z						biological_process											owl:Class	
GO:0102222	biolink:NamedThing	obsolete 6-phosophogluco-3-phosphogluco-starch phosphatase activity	OBSOLETE. Catalysis of the reaction: m+q H2O + a 6-phosphogluco-3-phosphogluco-amylopectin <=> m+q hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15220			This term was obsoleted because it was created by error.					True		MetaCyc:RXN-12218		molecular_function											owl:Class	
GO:0042993	biolink:NamedThing	obsolete positive regulation of transcription factor import into nucleus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.	got7fsn_ti	upregulation of transcription factor import into nucleus|positive regulation of transcription factor transport from cytoplasm to nucleus|up-regulation of transcription factor import into nucleus|positive regulation of transcription factor-nucleus import|stimulation of transcription factor import into nucleus|up regulation of transcription factor import into nucleus|positive regulation of transcription factor import into cell nucleus|activation of transcription factor import into nucleus				The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0042307				True				biological_process											owl:Class	
GO:1905207	biolink:NamedThing	regulation of cardiocyte differentiation	Any process that modulates the frequency, rate or extent of cardiocyte differentiation.	got7fsn_ti	regulation of cardiac cell differentiation|regulation of heart cell differentiation						bc	2016-06-02T07:20:01Z						biological_process											owl:Class	
GO:0010760	biolink:NamedThing	negative regulation of macrophage chemotaxis	Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0072091	biolink:NamedThing	regulation of stem cell proliferation	Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.	got7fsn_ti							mah	2010-02-08T02:09:03Z						biological_process											owl:Class	
GO:0045704	biolink:NamedThing	regulation of salivary gland boundary specification	Any process that modulates the frequency, rate or extent of salivary gland determination.	got7fsn_ti	regulation of salivary gland determination													biological_process											owl:Class	
GO:0033492	biolink:NamedThing	esculetin metabolic process	The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin.	got7fsn_ti	esculetin metabolism													biological_process											owl:Class	
GO:1905275	biolink:NamedThing	Rohon-Beard neuron differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron.	got7fsn_ti							cjm	2016-06-16T23:17:04Z						biological_process											owl:Class	
CHEBI:64413	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031451	biolink:NamedThing	positive regulation of slow-twitch skeletal muscle fiber contraction	Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction.	got7fsn_ti	positive regulation of slow-twitch skeletal muscle contraction|activation of slow-twitch skeletal muscle contraction|up-regulation of slow-twitch skeletal muscle contraction|up regulation of slow-twitch skeletal muscle contraction|stimulation of slow-twitch skeletal muscle contraction|upregulation of slow-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:1990824	biolink:NamedThing	obsolete magnesium-dependent protein complex	OBSOLETE. A protein complex that depends on magnesium in order for one or more of its components to remain a part of the complex.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-08-19T17:11:43Z		True				cellular_component											owl:Class	
GO:1900660	biolink:NamedThing	positive regulation of emericellamide biosynthetic process	Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process.	got7fsn_ti	upregulation of emericellamide anabolism|up-regulation of emericellamide biosynthesis|up regulation of emericellamide biosynthesis|activation of emericellamide anabolism|up-regulation of emericellamide synthesis|activation of emericellamide biosynthesis|positive regulation of emericellamide formation|upregulation of emericellamide biosynthetic process|up regulation of emericellamide formation|upregulation of emericellamide formation|activation of emericellamide biosynthetic process|activation of emericellamide synthesis|upregulation of emericellamide synthesis|up-regulation of emericellamide formation|positive regulation of emericellamide synthesis|positive regulation of emericellamide anabolism|up-regulation of emericellamide anabolism|up regulation of emericellamide synthesis|up regulation of emericellamide anabolism|positive regulation of emericellamide biosynthesis|up-regulation of emericellamide biosynthetic process|up regulation of emericellamide biosynthetic process|activation of emericellamide formation|upregulation of emericellamide biosynthesis						di	2012-05-22T04:10:51Z						biological_process											owl:Class	
CHEBI:15075	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003772	biolink:NamedThing	obsolete co-chaperonin activity	OBSOLETE. Co-chaperonins are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperonins by themselves do not possess chaperone activity.	got7fsn_ti	co-chaperonin activity				This term was made obsolete because it represents a class of gene products rather than a molecular function.	GO:0051087|GO:0006457|GO:0044183				True				molecular_function											owl:Class	
GO:0000233	biolink:NamedThing	obsolete cytoplasmic interphase chromosome	OBSOLETE. A chromosome found in the cytoplasm during interphase.	got7fsn_ti	cytoplasmic interphase chromosome				This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000229				True				cellular_component											owl:Class	
GO:2001267	biolink:NamedThing	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.	got7fsn_ti	regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|regulation of initiator caspase activity						pr	2011-12-13T07:56:13Z						biological_process											owl:Class	
GO:1903199	biolink:NamedThing	negative regulation of L-dopa decarboxylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity.	got7fsn_ti	downregulation of DDC activity|negative regulation of DOPA decarboxylase activity|negative regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|down-regulation of DDC activity|down regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|inhibition of L-dopa decarboxylase activity|downregulation of DOPA decarboxylase activity|downregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|down-regulation of DOPA decarboxylase activity|down regulation of L-dopa decarboxylase activity|negative regulation of DDC activity|inhibition of DOPA decarboxylase activity|inhibition of DDC activity|down regulation of DDC activity|down-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|down-regulation of L-dopa decarboxylase activity|down regulation of DOPA decarboxylase activity|downregulation of L-dopa decarboxylase activity|inhibition of 4-dihydroxyl-L-phenylalanine decarboxylase activity						bf	2014-07-21T09:32:37Z						biological_process											owl:Class	
GO:0097290	biolink:NamedThing	alpha-ribazole biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).	got7fsn_ti	alpha-ribazole anabolism|alpha-ribazole biosynthesis|alpha-ribazole synthesis|alpha-ribazole formation						pr	2012-04-25T11:51:07Z						biological_process											owl:Class	
GO:1905594	biolink:NamedThing	resveratrol binding	Binding to resveratrol.	got7fsn_ti					(5-(aziridin-1-yl)-2,4-dinitrobenzamide		pga	2016-10-25T15:23:37Z						molecular_function											owl:Class	
GO:0006184	biolink:NamedThing	obsolete GTP catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.	got7fsn_ti	GTP degradation|GTP breakdown|GTP catabolism|GTP hydrolysis				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0003924				True				biological_process											owl:Class	
GO:1905800	biolink:NamedThing	negative regulation of intraciliary retrograde transport	Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport.	got7fsn_ti	down regulation of intraflagellar retrograde transport|downregulation of intraciliary retrograde transport|negative regulation of intraflagellar retrograde transport|inhibition of intraciliary retrograde transport|down-regulation of intraciliary retrograde transport|down-regulation of intraflagellar retrograde transport|down regulation of intraciliary retrograde transport|downregulation of intraflagellar retrograde transport|inhibition of intraflagellar retrograde transport						hbye	2017-01-11T12:58:26Z						biological_process											owl:Class	
GO:2000041	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in axis elongation	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.	got7fsn_ti							dph	2010-08-18T02:47:54Z						biological_process											owl:Class	
GO:0006148	biolink:NamedThing	inosine catabolic process	The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.	got7fsn_ti	inosine breakdown|inosine degradation|inosine catabolism													biological_process											owl:Class	
GO:1902693	biolink:NamedThing	superoxide dismutase complex	A protein complex which is capable of superoxide dismutase activity.	got7fsn_ti					An example of this is SOD1 in Saccharomyces cerevisiae S288c (UniProt symbol P00445) in PMID:10026301.		bhm	2014-02-18T11:10:11Z						cellular_component											owl:Class	
GO:0038076	biolink:NamedThing	obsolete MAP kinase kinase activity involved in innate immune response	OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to an innate immune response.	got7fsn_ti	MAPKK activity involved in innate immune response|MAP2K activity involved in innate immune response				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:35:52Z		True				molecular_function											owl:Class	
GO:1904528	biolink:NamedThing	positive regulation of microtubule binding	Any process that activates or increases the frequency, rate or extent of microtubule binding.	got7fsn_ti	up-regulation of microtubule/chromatin interaction|upregulation of microtubule binding|positive regulation of microtubule/chromatin interaction|activation of microtubule binding|positive regulation of microtubule severing activity|up-regulation of microtubule severing activity|activation of microtubule/chromatin interaction|up-regulation of microtubule binding|upregulation of microtubule/chromatin interaction|up regulation of microtubule binding|upregulation of microtubule severing activity|activation of microtubule severing activity|up regulation of microtubule severing activity|up regulation of microtubule/chromatin interaction						als	2015-07-30T10:32:36Z						biological_process											owl:Class	
GO:0016293	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900504	biolink:NamedThing	negative regulation of cellulosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly.	got7fsn_ti	down-regulation of cellulosome assembly|inhibition of cellulosome assembly|down regulation of cellulosome assembly|downregulation of cellulosome assembly						tt	2012-05-02T03:58:26Z						biological_process											owl:Class	
GO:0015376	biolink:NamedThing	obsolete betaine/GABA:sodium symporter activity	OBSOLETE. Catalysis of the reaction: (betaine or gamma-aminobutyric acid)(out) + Na+(out) = (betaine or gamma-aminobutyric acid)(in) + Na+(in).	got7fsn_ti	betaine/GABA:sodium symporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015185|GO:0015199|GO:0005332|GO:0015370				True				molecular_function											owl:Class	
GO:0086101	biolink:NamedThing	endothelin receptor signaling pathway involved in heart process	An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.	got7fsn_ti	endothelin receptor signalling pathway involved in heart process						bf							biological_process											owl:Class	
GO:2001194	biolink:NamedThing	regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.	got7fsn_ti	regulation of lysine biosynthesis via aminoadipic acid and saccharopine|regulation of lysine biosynthetic process via aminoadipic acid and saccharopine						mcc	2011-11-03T07:57:11Z						biological_process											owl:Class	
GO:0045102	biolink:NamedThing	obsolete peripherin	OBSOLETE. Peripherin is a type III intermediate filament protein found in neurons of the peripheral nervous system.	got7fsn_ti	peripherin				This term was made obsolete because it represents a gene product.	GO:0045098				True				cellular_component											owl:Class	
GO:0032481	biolink:NamedThing	positive regulation of type I interferon production	Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	positive regulation of type I IFN production|upregulation of type I interferon production|activation of type I interferon production|up regulation of type I interferon production|stimulation of type I interferon production|up-regulation of type I interferon production													biological_process											owl:Class	
GO:1902930	biolink:NamedThing	regulation of alcohol biosynthetic process	Any process that modulates the frequency, rate or extent of alcohol biosynthetic process.	got7fsn_ti	regulation of alcohol biosynthesis|regulation of solventogenesis|regulation of alcohol synthesis|regulation of alcohol formation|regulation of alcohol anabolism						tt	2014-04-22T21:55:03Z						biological_process											owl:Class	
GO:1901301	biolink:NamedThing	regulation of cargo loading into COPII-coated vesicle	Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle.	got7fsn_ti	regulation of COPII coat-cargo complex assembly|regulation of cargo selection into COPII-coated vesicle|regulation of cargo loading into COPII vesicle						bf	2012-08-21T13:03:00Z						biological_process											owl:Class	
GO:1900472	biolink:NamedThing	obsolete positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of phosphatidylcholine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine formation by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T08:13:36Z		True				biological_process											owl:Class	
GO:0002647	biolink:NamedThing	negative regulation of central tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction.	got7fsn_ti	downregulation of central tolerance induction|down-regulation of central tolerance induction|down regulation of central tolerance induction|inhibition of central tolerance induction													biological_process											owl:Class	
GO:0072198	biolink:NamedThing	mesenchymal cell proliferation involved in ureter development	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.	got7fsn_ti	ureter mesenchymal cell proliferation|ureteral mesenchymal cell proliferation						mah	2010-03-01T03:24:41Z						biological_process											owl:Class	
GO:0009477	biolink:NamedThing	obsolete cytochrome c1	OBSOLETE. A cytochrome c that is an integral component of the mitochondrial respiratory complex III. Functions as an electron donor to cytochrome c.	got7fsn_ti	cytochrome c1			GO:0004129	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0075272	biolink:NamedThing	regulation of zygosporangium development	Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.	got7fsn_ti														biological_process											owl:Class	
GO:0075205	biolink:NamedThing	obsolete modulation by host of symbiont cAMP-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The cAMP-mediated signal transduction is defined as a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by host of symbiont cAMP-mediated signalling|regulation by host of symbiont cAMP-mediated signaling|modulation by host of symbiont cAMP-mediated signaling				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:1904537	biolink:NamedThing	negative regulation of mitotic telomere tethering at nuclear periphery	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.	got7fsn_ti	inhibition of mitotic telomere tethering at nuclear periphery|downregulation of mitotic telomere tethering at nuclear periphery|down-regulation of mitotic telomere tethering at nuclear periphery|down regulation of mitotic telomere tethering at nuclear periphery						al	2015-08-04T14:24:32Z						biological_process											owl:Class	
GO:0120161	biolink:NamedThing	regulation of cold-induced thermogenesis	Any process that modulates the frequency, rate or extent of cold-induced thermogenesis.	got7fsn_ti	regulation of CIT						krc	2018-05-14T17:03:19Z						biological_process											owl:Class	
GO:0099177	biolink:NamedThing	regulation of trans-synaptic signaling	Any process that modulates the frequency, rate or extent of trans-synaptic signaling.	got7fsn_ti														biological_process											owl:Class	
GO:0050923	biolink:NamedThing	regulation of negative chemotaxis	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.	got7fsn_ti														biological_process											owl:Class	
GO:0009871	biolink:NamedThing	jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway	The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance.	got7fsn_ti	jasmonic acid and ethene-dependent systemic resistance, ethene mediated signaling pathway|jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signaling pathway|jasmonic acid/ethene-dependent systemic resistance, ethene mediated signaling pathway|ethylene mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)|jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signalling pathway|jasmonic acid/ethene-dependent systemic resistance, ethene mediated signalling pathway|ethene mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)													biological_process											owl:Class	
GO:1904778	biolink:NamedThing	positive regulation of protein localization to cell cortex	Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.	got7fsn_ti	positive regulation of protein localisation to cell cortex|activation of protein localisation to cell cortex|up-regulation of protein localisation to cell cortex|upregulation of protein localization to cell cortex|up regulation of protein localization to cell cortex|activation of protein localization to cell cortex|upregulation of protein localisation to cell cortex|up-regulation of protein localization to cell cortex|up regulation of protein localisation to cell cortex				An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.		es	2015-10-29T16:55:15Z						biological_process											owl:Class	
GO:0070758	biolink:NamedThing	regulation of interleukin-35-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor.	got7fsn_ti	regulation of interleukin-35-mediated signalling pathway|regulation of IL-35-mediated signaling pathway						mah	2009-06-23T01:58:43Z						biological_process											owl:Class	
GO:0046003	biolink:NamedThing	negative regulation of syncytial blastoderm mitotic cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.	got7fsn_ti	downregulation of progression through syncytial blastoderm mitotic cell cycle|down-regulation of progression through syncytial blastoderm mitotic cell cycle|negative regulation of progression through syncytial blastoderm mitotic cell cycle|down regulation of progression through syncytial blastoderm mitotic cell cycle|inhibition of progression through syncytial blastoderm mitotic cell cycle|negative regulation of syncytial blastoderm cell cycle progression													biological_process											owl:Class	
GO:0042189	biolink:NamedThing	vanillin biosynthetic process	The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.	got7fsn_ti	vanillic aldehyde biosynthetic process|vanillin anabolism|vanillin biosynthesis|vanillin formation|vanillin synthesis|vanillic aldehyde biosynthesis													biological_process											owl:Class	
GO:0019468	biolink:NamedThing	nopaline catabolic process	The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.	got7fsn_ti	nopaline catabolism|nopaline degradation|nopaline breakdown											MetaCyc:NOPALINEDEG-PWY		biological_process											owl:Class	
GO:0048298	biolink:NamedThing	positive regulation of isotype switching to IgA isotypes	Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.	got7fsn_ti	stimulation of isotype switching to IgA isotypes|up-regulation of isotype switching to IgA isotypes|positive regulation of class switching to IgA isotypes|positive regulation of class switch recombination to IgA isotypes|activation of isotype switching to IgA isotypes|upregulation of isotype switching to IgA isotypes|positive regulation of isotype switch recombination to IgA isotypes|up regulation of isotype switching to IgA isotypes													biological_process											owl:Class	
GO:1903754	biolink:NamedThing	cortical microtubule plus-end	The plus-end of a cortical microtubule.	got7fsn_ti	cortical microtubule plus end						jl	2014-12-16T15:41:38Z						cellular_component											owl:Class	
GO:0034350	biolink:NamedThing	regulation of glial cell apoptotic process	Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.	got7fsn_ti	regulation of glial cell apoptosis													biological_process											owl:Class	
GO:1905166	biolink:NamedThing	negative regulation of lysosomal protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process.	got7fsn_ti	down regulation of cellular protein breakdown in lysosome|inhibition of cellular protein catabolic process in lysosome|downregulation of cellular protein breakdown in lysosome|down-regulation of lysosomal protein catabolism|down regulation of cellular protein catabolism in lysosome|inhibition of lysosomal proteolysis|downregulation of cellular protein catabolism in lysosome|inhibition of proteolysis within lysosome|inhibition of cellular protein breakdown in lysosome|inhibition of lysosomal protein degradation|down regulation of lysosomal proteolysis|negative regulation of cellular protein breakdown in lysosome|negative regulation of lysosomal protein degradation|negative regulation of cellular protein catabolic process in lysosome|negative regulation of lysosomal protein catabolism|down-regulation of lysosomal protein catabolic process|downregulation of lysosomal proteolysis|negative regulation of cellular protein catabolism in lysosome|down regulation of cellular protein catabolic process in lysosome|inhibition of lysosomal protein catabolic process|down-regulation of lysosomal proteolysis|negative regulation of lysosomal proteolysis|downregulation of lysosomal protein degradation|down-regulation of proteolysis within lysosome|downregulation of lysosomal protein catabolic process|down-regulation of cellular protein degradation in lysosome|down-regulation of cellular protein catabolic process in lysosome|downregulation of cellular protein degradation in lysosome|negative regulation of proteolysis within lysosome|downregulation of cellular protein catabolic process in lysosome|down-regulation of cellular protein breakdown in lysosome|down regulation of lysosomal protein degradation|down regulation of lysosomal protein catabolism|down regulation of proteolysis within lysosome|down regulation of cellular protein degradation in lysosome|down-regulation of cellular protein catabolism in lysosome|inhibition of cellular protein catabolism in lysosome|inhibition of cellular protein degradation in lysosome|down-regulation of lysosomal protein degradation|inhibition of lysosomal protein catabolism|downregulation of lysosomal protein catabolism|negative regulation of cellular protein degradation in lysosome|downregulation of proteolysis within lysosome|down regulation of lysosomal protein catabolic process						bf	2016-04-26T12:10:10Z						biological_process											owl:Class	
GO:1990278	biolink:NamedThing	obsolete positive regulation of MBF transcription factor activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor MBF.	got7fsn_ti	positive regulation of MBF transcription factor activity				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-01-29T14:43:44Z		True				biological_process											owl:Class	
GO:1905887	biolink:NamedThing	autoinducer AI-2 transmembrane transport	The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing.	got7fsn_ti	AI-2 transmembrane transport|autoinducer 2 transmembrane transport|(2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol transmembrane transport						dos	2017-01-31T14:34:50Z						biological_process											owl:Class	
GO:1902543	biolink:NamedThing	negative regulation of protein localization to mitotic spindle pole body	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body.	got7fsn_ti	down regulation of protein localisation to mitotic spindle pole body|inhibition of protein localisation to mitotic spindle pole body|inhibition of protein localization to mitotic spindle pole body|downregulation of protein localization to mitotic spindle pole body|down-regulation of protein localisation in mitotic spindle pole body|negative regulation of protein localisation to mitotic spindle pole body|down regulation of protein localization to mitotic spindle pole body|downregulation of protein localisation to mitotic spindle pole body|down-regulation of protein localization to mitotic spindle pole body|down-regulation of protein localisation to mitotic spindle pole body						al	2013-12-04T13:47:18Z						biological_process											owl:Class	
GO:0016466	biolink:NamedThing	obsolete hydrogen-translocating A-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in archae.	got7fsn_ti	hydrogen-translocating A-type ATPase activity|proton-translocating A-type ATPase activity			GO:0046961	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0007016	biolink:NamedThing	obsolete cytoskeletal anchoring at plasma membrane	OBSOLETE. A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.	got7fsn_ti	cytoskeletal anchoring activity	https://github.com/geneontology/go-ontology/issues/19119			This term was obsoleted because it represents a molecular function.	GO:0106006|GO:0007010				True				biological_process											owl:Class	
GO:1901133	biolink:NamedThing	kanamycin biosynthetic process	The chemical reactions and pathways resulting in the formation of kanamycin.	got7fsn_ti	kanamycin biosynthesis|kanamycin anabolism|kanamycin synthesis|kanamycin formation						yaf	2012-07-11T03:27:32Z						biological_process											owl:Class	
GO:0004986	biolink:NamedThing	obsolete delta-opioid receptor activity	OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands.	got7fsn_ti	delta-opioid receptor activity				This term was made obsolete because the receptor is defined based on its pharmacological properties.	GO:0038046				True		Wikipedia:Delta_Opioid_receptor		molecular_function											owl:Class	
GO:0009839	biolink:NamedThing	obsolete SCF complex substrate recognition subunit	OBSOLETE. The portion of the SCF ubiquitin ligase complex that contains sites required for recognition (and recruitment) of the substrate to the complex.	got7fsn_ti	SCF complex substrate recognition subunit			GO:0019005	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:0033084	biolink:NamedThing	regulation of immature T cell proliferation in thymus	Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus.	got7fsn_ti	regulation of thymic T cell proliferation|regulation of thymocyte proliferation|regulation of thymocyte cell proliferation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0140501	biolink:NamedThing	positive regulation of reticulophagy	Any process that increases the frequency, rate or extent of reticulophagy.	got7fsn_ti	positive regulation of endoplasmic reticulum degradation|positive regulation of ER autophagy|positive regulation of ER degradation|positive regulation of autophagy of the ER|positive regulation of endoplasmic reticulum autophagy|positive regulation of ER-phagy|positive regulation of autophagy of the endoplasmic reticulum	https://github.com/geneontology/go-ontology/issues/19860					pg	2020-08-10T12:01:35Z						biological_process											owl:Class	
GO:0052522	biolink:NamedThing	obsolete positive regulation by organism of phagocytosis in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	activation by organism of phagocytosis in other organism during symbiotic interaction|positive regulation by organism of phagocytosis in other organism during symbiotic interaction|up regulation by organism of phagocytosis in other organism during symbiotic interaction|up-regulation by organism of phagocytosis in other organism during symbiotic interaction|stimulation by organism of phagocytosis in other organism during symbiotic interaction|upregulation by organism of phagocytosis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18562			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0039534	biolink:NamedThing	negative regulation of MDA-5 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.	got7fsn_ti	negative regulation of MDA5 signaling pathway|negative regulation of melanoma differentiation-associated gene 5 signaling pathway|negative regulation of IFIH1 signaling pathway|negative regulation of MDA-5 signalling pathway						bf	2012-01-03T11:21:20Z						biological_process											owl:Class	
GO:1905482	biolink:NamedThing	obsolete cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint	OBSOLETE. Any cytoplasmic sequestering of protein that is involved in G2 DNA damage checkpoint.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		vw	2016-09-22T18:23:55Z		True				biological_process											owl:Class	
GO:0045091	biolink:NamedThing	regulation of single stranded viral RNA replication via double stranded DNA intermediate	Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.	got7fsn_ti	regulation of retroviral genome replication													biological_process											owl:Class	
GO:0019469	biolink:NamedThing	octopine catabolic process	The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.	got7fsn_ti	octopine degradation|octopine catabolism|octopine breakdown											MetaCyc:OCTOPINEDEG-PWY		biological_process											owl:Class	
GO:0060551	biolink:NamedThing	regulation of fructose 1,6-bisphosphate metabolic process	Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.	got7fsn_ti							dph	2009-04-13T02:20:04Z						biological_process											owl:Class	
GO:0015352	biolink:NamedThing	obsolete secondary active sterol transmembrane transporter activity	OBSOLETE. Enables the transfer of sterol from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.	got7fsn_ti	sterol porter activity				This term was obsoleted because there is no evidence that this function exists.					True				molecular_function											owl:Class	
GO:0050983	biolink:NamedThing	obsolete deoxyhypusine biosynthetic process from spermidine	OBSOLETE. The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+.	got7fsn_ti	spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase|spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase|deoxyhypusine formation from spermidine, using deoxyhypusine synthase|deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase|deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase|[eIF-5A]-deoxyhypusine synthase activity|deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase|(4-aminobutyl)lysine synthase activity|spermidine degradation to deoxyhypusine, using deoxyhypusine synthase				The reason for obsoletion is that although GO:0050983 is described as a multistep process, the entire reaction is carried out by a single enzyme, therefore we would define it as the molecular function GO:0034038 deoxyhypusine synthase activity.	GO:0034038				True		MetaCyc:2.5.1.46-RXN|EC:2.5.1.46		biological_process											owl:Class	
GO:1903447	biolink:NamedThing	geraniol catabolic process	The chemical reactions and pathways resulting in the breakdown of geraniol.	got7fsn_ti	geraniol breakdown|geraniol degradation|geraniol catabolism						di	2014-09-19T08:18:44Z						biological_process											owl:Class	
GO:0004786	biolink:NamedThing	obsolete Mn, Fe superoxide dismutase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Mn, Fe superoxide dismutase				This term was made obsolete because the function is covered by an existing term.	GO:0004784				True				molecular_function											owl:Class	
GO:1903416	biolink:NamedThing	response to glycoside	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.	got7fsn_ti	cellular response to ouabain						rl	2014-09-05T12:41:01Z						biological_process											owl:Class	
GO:0046069	biolink:NamedThing	cGMP catabolic process	The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate.	got7fsn_ti	cGMP catabolism|cGMP breakdown|cGMP degradation													biological_process											owl:Class	
GO:1901215	biolink:NamedThing	negative regulation of neuron death	Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.	got7fsn_ti	down regulation of neuronal cell death|downregulation of neuronal cell death|inhibition of neuronal cell death|down-regulation of neuron cell death|downregulation of neuron cell death|negative regulation of neuronal cell death|down regulation of neuron death|negative regulation of neuron cell death|down-regulation of neuron death|down-regulation of neuronal cell death|down regulation of neuron cell death|downregulation of neuron death|inhibition of neuron death|inhibition of neuron cell death						rph	2012-08-02T09:58:07Z						biological_process											owl:Class	
GO:1901675	biolink:NamedThing	negative regulation of histone H3-K27 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 acetylation.	got7fsn_ti	down-regulation of histone H3K27 acetylation|inhibition of histone H3-K27 acetylation|inhibition of histone H3K27 acetylation|down regulation of histone H3K27 acetylation|downregulation of histone H3-K27 acetylation|negative regulation of histone H3K27 acetylation|down regulation of histone H3 acetylation at K27|downregulation of histone H3K27 acetylation|negative regulation of histone H3 acetylation at K27|down-regulation of histone H3 acetylation at K27|down regulation of histone H3-K27 acetylation|inhibition of histone H3 acetylation at K27|downregulation of histone H3 acetylation at K27|down-regulation of histone H3-K27 acetylation						vk	2012-11-22T12:06:40Z						biological_process											owl:Class	
GO:1900876	biolink:NamedThing	nonadec-1-ene metabolic process	The chemical reactions and pathways involving nonadec-1-ene.	got7fsn_ti	nonadec-1-ene metabolism						tt	2012-06-13T01:52:09Z						biological_process											owl:Class	
GO:0050425	biolink:NamedThing	obsolete carboxypeptidase B activity	OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid.	got7fsn_ti	protaminase activity|pancreatic carboxypeptidase B|carboxypeptidase B activity|peptidyl-L-lysine [L-arginine]hydrolase activity|tissue carboxypeptidase B			GO:0004181	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0034345	biolink:NamedThing	negative regulation of type III interferon production	Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	inhibition of type III interferon production|negative regulation of type III IFN production|downregulation of type III interferon production|down-regulation of type III interferon production|down regulation of type III interferon production				Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.									biological_process											owl:Class	
GO:1901058	biolink:NamedThing	p-hydroxyphenyl lignin metabolic process	The chemical reactions and pathways involving p-hydroxyphenyl lignin.	got7fsn_ti	H-lignin metabolic process|p-hydroxyphenyl lignin metabolism						tt	2012-06-29T12:31:57Z						biological_process											owl:Class	
GO:1900168	biolink:NamedThing	positive regulation of glial cell-derived neurotrophic factor production	Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor production.	got7fsn_ti	positive regulation of glial cell-derived neurotrophic factor secretion|activation of glial cell line-derived neurotrophic factor secretion|positive regulation of glial cell line-derived neurotrophic factor secretion|positive regulation of GDNF production						yaf	2012-03-08T03:44:47Z						biological_process											owl:Class	
GO:2000130	biolink:NamedThing	positive regulation of octopamine signaling pathway	Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway.	got7fsn_ti	positive regulation of octopamine signalling pathway						mah	2010-09-29T09:29:47Z						biological_process											owl:Class	
GO:0090240	biolink:NamedThing	positive regulation of histone H4 acetylation	Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.	got7fsn_ti							tb	2010-01-20T03:48:09Z						biological_process											owl:Class	
GO:1900975	biolink:NamedThing	negative regulation of tatiopterin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process.	got7fsn_ti	down regulation of tatiopterin anabolism|negative regulation of tatiopterin synthesis|down-regulation of tatiopterin biosynthesis|downregulation of tatiopterin synthesis|negative regulation of tatiopterin anabolism|down-regulation of tatiopterin biosynthetic process|downregulation of tatiopterin anabolism|down regulation of tatiopterin biosynthetic process|negative regulation of tatiopterin formation|downregulation of tatiopterin formation|inhibition of tatiopterin anabolism|downregulation of tatiopterin biosynthetic process|down-regulation of tatiopterin anabolism|down regulation of tatiopterin synthesis|inhibition of tatiopterin biosynthesis|downregulation of tatiopterin biosynthesis|down-regulation of tatiopterin synthesis|negative regulation of tatiopterin biosynthesis|inhibition of tatiopterin biosynthetic process|inhibition of tatiopterin synthesis|down regulation of tatiopterin biosynthesis|down-regulation of tatiopterin formation|inhibition of tatiopterin formation|down regulation of tatiopterin formation						tt	2012-06-14T04:02:06Z						biological_process											owl:Class	
GO:1900697	biolink:NamedThing	positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.	got7fsn_ti	up regulation of N',N'',N'''-triacetylfusarinine C synthesis|activation of N',N'',N'''-triacetylfusarinine C formation|up-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|activation of N',N'',N'''-triacetylfusarinine C biosynthetic process|upregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|upregulation of N',N'',N'''-triacetylfusarinine C formation|upregulation of N',N'',N'''-triacetylfusarinine C biosynthesis|up-regulation of N',N'',N'''-triacetylfusarinine C anabolism|up regulation of N',N'',N'''-triacetylfusarinine C anabolism|up regulation of N',N'',N'''-triacetylfusarinine C formation|up-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|positive regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|positive regulation of N',N'',N'''-triacetylfusarinine C anabolism|up regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|upregulation of N',N'',N'''-triacetylfusarinine C synthesis|activation of N',N'',N'''-triacetylfusarinine C synthesis|up regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|activation of N',N'',N'''-triacetylfusarinine C anabolism|upregulation of N',N'',N'''-triacetylfusarinine C anabolism|positive regulation of N',N'',N'''-triacetylfusarinine C formation|up-regulation of N',N'',N'''-triacetylfusarinine C formation|activation of N',N'',N'''-triacetylfusarinine C biosynthesis|up-regulation of N',N'',N'''-triacetylfusarinine C synthesis|positive regulation of N',N'',N'''-triacetylfusarinine C synthesis						di	2012-05-22T04:54:56Z						biological_process											owl:Class	
GO:0038103	biolink:NamedThing	activin receptor antagonist activity involved in negative regulation of nodal signaling pathway	Interacting with an activin receptor to reduce the action of the agonist nodal. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.	got7fsn_ti	activin receptor antagonist activity involved in negative regulation of nodal signalling pathway|nodal antagonist activity						bf	2012-02-17T11:30:21Z						molecular_function											owl:Class	
GO:0090208	biolink:NamedThing	positive regulation of triglyceride metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.	got7fsn_ti							tb	2009-12-23T10:35:06Z						biological_process											owl:Class	
GO:0036314	biolink:NamedThing	response to sterol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.	got7fsn_ti							bf	2012-08-21T14:50:14Z						biological_process											owl:Class	
GO:1900378	biolink:NamedThing	positive regulation of secondary metabolite biosynthetic process	Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.	got7fsn_ti	up regulation of secondary metabolite biosynthesis|upregulation of secondary metabolite biosynthetic process|upregulation of secondary metabolite biosynthesis|up-regulation of secondary metabolite biosynthesis|up regulation of secondary metabolite biosynthetic process|positive regulation of secondary metabolite biosynthesis|up-regulation of secondary metabolite biosynthetic process|activation of secondary metabolite biosynthetic process|activation of secondary metabolite biosynthesis						di	2012-04-17T01:55:41Z						biological_process											owl:Class	
GO:0004444	biolink:NamedThing	obsolete inositol-1,4,5-trisphosphate 1-phosphatase	OBSOLETE. The removal of a phosphate group from the carbon-1 position of D-myo-inositol 1,4,5-trisphosphate.	got7fsn_ti	inositol-1,4,5-trisphosphate 1-phosphatase				This term was made obsolete because the existence of this function has not been established.	GO:0046030				True				molecular_function											owl:Class	
GO:1901857	biolink:NamedThing	positive regulation of cellular respiration	Any process that activates or increases the frequency, rate or extent of cellular respiration.	got7fsn_ti	up-regulation of cellular respiration|up regulation of cellular respiration|upregulation of oxidative metabolic process|upregulation of respiration|up regulation of respiration|positive regulation of oxidative metabolic process|up-regulation of oxidative metabolism|activation of cellular respiration|up-regulation of oxidative metabolic process|upregulation of cellular respiration|upregulation of oxidative metabolism|up regulation of oxidative metabolism|activation of oxidative metabolic process|activation of oxidative metabolism|positive regulation of oxidative metabolism|up regulation of oxidative metabolic process|activation of respiration|up-regulation of respiration|positive regulation of respiration						yaf	2013-02-01T09:56:28Z						biological_process											owl:Class	
GO:0099113	biolink:NamedThing	negative regulation of presynaptic cytosolic calcium concentration	Any process that decreases the concentration of calcium ions in the presynaptic cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:0019857	biolink:NamedThing	5-methylcytosine metabolic process	The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA.	got7fsn_ti	5-methylcytosine metabolism													biological_process											owl:Class	
GO:1901496	biolink:NamedThing	positive regulation of cysteine metabolic process	Any process that activates or increases the frequency, rate or extent of cysteine metabolic process.	got7fsn_ti	activation of cysteine metabolism|up-regulation of cysteine metabolic process|positive regulation of cysteine metabolism|up-regulation of cysteine metabolism|upregulation of cysteine metabolic process|up regulation of cysteine metabolic process|upregulation of cysteine metabolism|up regulation of cysteine metabolism|activation of cysteine metabolic process						vw	2012-10-16T14:28:51Z						biological_process											owl:Class	
GO:1903204	biolink:NamedThing	negative regulation of oxidative stress-induced neuron death	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death.	got7fsn_ti	inhibition of neuronal cell death in response to oxidative stress|down-regulation of oxidative stress-induced neuron death|down-regulation of neuronal cell death in response to oxidative stress|inhibition of oxidative stress-induced neuron death|down regulation of oxidative stress-induced neuron death|downregulation of oxidative stress-induced neuron death|downregulation of neuronal cell death in response to oxidative stress|inhibition of neuron death in response to oxidative stress|neuroprotection against oxidative stress|down regulation of neuron death in response to oxidative stress|negative regulation of neuronal cell death in response to oxidative stress|down regulation of neuronal cell death in response to oxidative stress|down-regulation of neuron death in response to oxidative stress|downregulation of neuron death in response to oxidative stress|neuronal protection under oxidative stress						bf	2014-07-21T16:17:36Z						biological_process											owl:Class	
GO:0016061	biolink:NamedThing	regulation of light-activated channel activity	Any process that modulates the frequency, rate or extent of light-activated channel activity.	got7fsn_ti														biological_process											owl:Class	
GO:1902262	biolink:NamedThing	apoptotic process involved in blood vessel morphogenesis	Any apoptotic process that is involved in blood vessel morphogenesis.	got7fsn_ti	signaling (initiator) caspase activity involved in patterning of blood vessels|apoptotic programmed cell death involved in patterning of blood vessels|type I programmed cell death involved in patterning of blood vessels|apoptosis involved in patterning of blood vessels|apoptotic program involved in patterning of blood vessels|apoptotic cell death involved in patterning of blood vessels|programmed cell death by apoptosis involved in patterning of blood vessels						dph	2013-06-25T16:16:00Z						biological_process											owl:Class	
GO:2000795	biolink:NamedThing	negative regulation of epithelial cell proliferation involved in lung morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.	got7fsn_ti							pr	2011-06-25T07:22:42Z						biological_process											owl:Class	
GO:0038070	biolink:NamedThing	obsolete MAP kinase kinase kinase activity involved in cell wall organization or biogenesis	OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.	got7fsn_ti	MAP kinase kinase kinase activity involved in cell wall biogenesis|MAPKKK activity involved in cell wall integrity|MAP3K activity involved in cell wall integrity				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-25T03:43:46Z		True				molecular_function											owl:Class	
GO:1905783	biolink:NamedThing	CENP-A containing nucleosome disassembly	The disaggregation of a CENP-A containing nucleosome into its constituent components.	got7fsn_ti	centromeric nucleosome disassembly|centromere specific nucleosome disassembly|centromere-specific nucleosome disassembly						vw	2017-01-05T09:19:07Z						biological_process											owl:Class	
GO:0035576	biolink:NamedThing	retinoic acid receptor signaling pathway involved in pronephric field specification	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop.	got7fsn_ti	retinoic acid receptor signalling pathway involved in pronephric field specification						bf	2010-10-05T01:19:35Z						biological_process											owl:Class	
GO:0051510	biolink:NamedThing	regulation of unidimensional cell growth	Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.	got7fsn_ti	regulation of cell elongation													biological_process											owl:Class	
GO:1904097	biolink:NamedThing	acid phosphatase complex	A protein complex which is capable of acid phosphatase activity.	got7fsn_ti					An example of this is ACPP in human (UniProt symbol P15309) in PMID:22389722 (inferred from physical interaction).		bhm	2015-03-27T14:36:36Z						cellular_component											owl:Class	
GO:2001015	biolink:NamedThing	negative regulation of skeletal muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.	got7fsn_ti							yaf	2011-08-11T08:54:41Z						biological_process											owl:Class	
CHEBI:26438	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052223	biolink:NamedThing	obsolete negative chemotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative chemotaxis in environment of other organism during symbiotic interaction|negative chemotaxis in response to environment of other organism	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:2000530	biolink:NamedThing	obsolete positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of insulin secretion involved in cellular response to glucose stimulus.	got7fsn_ti	positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of regulation of insulin secretion in response to glucose						yaf	2011-03-24T09:27:37Z		True				biological_process											owl:Class	
GO:1900743	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to pH	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.	got7fsn_ti	upregulation of filamentous growth of a population of unicellular organisms in response to pH|up regulation of filamentous growth of a population of unicellular organisms in response to pH|activation of filamentous growth of a population of unicellular organisms in response to pH|up-regulation of filamentous growth of a population of unicellular organisms in response to pH						di	2012-05-28T02:35:11Z						biological_process											owl:Class	
GO:1905877	biolink:NamedThing	obsolete invadopodium assembly	OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form an invadopodium.	got7fsn_ti	invadopodium formation				This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-01-27T20:44:07Z		True				biological_process											owl:Class	
GO:1900674	biolink:NamedThing	olefin biosynthetic process	The chemical reactions and pathways resulting in the formation of olefin.	got7fsn_ti	olefin biosynthesis|olefin synthesis|olefin formation|olefin anabolism						tt	2012-05-22T04:25:03Z						biological_process											owl:Class	
GO:1900849	biolink:NamedThing	regulation of pseurotin A biosynthetic process	Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process.	got7fsn_ti	regulation of Pseurotin formation|regulation of Pseurotin anabolism|regulation of pseurotin A anabolism|regulation of Pseurotin biosynthetic process|regulation of pseurotin A synthesis|regulation of pseurotin A biosynthesis|regulation of Pseurotin synthesis|regulation of Pseurotin biosynthesis|regulation of pseurotin A formation						di	2012-06-07T09:45:27Z						biological_process											owl:Class	
GO:0006926	biolink:NamedThing	obsolete virus-infected cell apoptotic process	OBSOLETE. Any apoptotic process in a cell infected with a virus.	got7fsn_ti	virus-infected cell programmed cell death by apoptosis|programmed cell death of virus-infected cells by apoptosis|virus-infected cell apoptotic process|virus-infected cell apoptosis|killing virus-infected cells|programmed cell death, virus-infected cells|apoptosis of virus-infected cells				This term was made obsolete because the meaning of the term is ambiguous, as it's possibly conflating at least two scenarios: 1) the organism apoptoses its own cell because it detects it is infected with a virus; 2) the virus induces apoptosis so the cell is lysed and the virus disseminated. Please consider using viral process terms to annotate viral proteins. As for the cellular apoptotic process, this likely occurs via the same mechanisms described by existing apoptotic process terms, so please consider using those to annotate cellular proteins.					True				biological_process											owl:Class	
GO:0004291	biolink:NamedThing	obsolete subtilisin activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.	got7fsn_ti	alcalase activity|maxatase activity|subtilisin S41|SP 266|genenase I|esperase activity|savinase activity|protease VIII|subtilisin DY|subtilisin activity|subtilisin BL|subtilopeptidase activity|savinase 8.0L|thermoase|subtilisin J|superase activity|bacillus subtilis alkaline proteinase activity|savinase 4.0T|bacillopeptidase B|alcalase 0.6L|savinase 32.0 L EX|protease XXVII|ALK-enzyme|bioprase APL 30|kazusase activity|bioprase AL 15|subtilisin sendai|protin A 3L|bacillus subtilis alkaline proteinase bioprase activity|bacillopeptidase A|savinase 16.0L|orientase 10B|subtilisin GX|opticlean|protease S|colistinase activity|thermoase PC 10|subtilisin E|alcalase 2.5L			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0120032	biolink:NamedThing	regulation of plasma membrane bounded cell projection assembly	Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13298					krc	2017-04-26T04:27:04Z						biological_process											owl:Class	
GO:0019059	biolink:NamedThing	obsolete initiation of viral infection	OBSOLETE. The set of processes involved in the start of virus infection of cells.	got7fsn_ti	initiation of viral infection				This term was made obsolete because it is ambiguous, and more specific terms have been created.	GO:0046718				True				biological_process											owl:Class	
GO:0061336	biolink:NamedThing	cell morphogenesis involved in Malpighian tubule morphogenesis	The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.	got7fsn_ti							dph	2010-09-28T02:11:47Z						biological_process											owl:Class	
GO:1901067	biolink:NamedThing	ferulate catabolic process	The chemical reactions and pathways resulting in the breakdown of ferulate.	got7fsn_ti	ferulate catabolism|ferulate degradation|ferulate breakdown						tt	2012-06-29T08:06:37Z						biological_process											owl:Class	
GO:0070688	biolink:NamedThing	obsolete MLL5-L complex	OBSOLETE. A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N-terminal subunit, beta-actin, and O-GlcNAc transferase; the human genes encoding the subunits are MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT, respectively.	got7fsn_ti					This term was made obsolete because there is no evidence for the existence of this complex.		mah	2009-06-03T11:50:18Z		True				cellular_component											owl:Class	
GO:1901335	biolink:NamedThing	lactone catabolic process	The chemical reactions and pathways resulting in the breakdown of lactone.	got7fsn_ti	lactone catabolism|lactone breakdown|lactone degradation						bf	2012-09-03T10:27:11Z						biological_process											owl:Class	
GO:1904373	biolink:NamedThing	response to kainic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.	got7fsn_ti							sl	2015-06-18T22:42:52Z						biological_process											owl:Class	
GO:1905894	biolink:NamedThing	regulation of cellular response to tunicamycin	Any process that modulates the frequency, rate or extent of cellular response to tunicamycin.	got7fsn_ti							bc	2017-02-01T11:36:34Z						biological_process											owl:Class	
GO:1905625	biolink:NamedThing	negative regulation of L-methionine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane.	got7fsn_ti							vw	2016-10-29T16:27:38Z						biological_process											owl:Class	
GO:0035419	biolink:NamedThing	obsolete activation of MAPK activity involved in innate immune response	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18000			This term was obsoleted because it should be represented as a GO-CAM model.		bf	2010-03-29T01:25:24Z		True				biological_process											owl:Class	
GO:2000962	biolink:NamedThing	positive regulation of cellooligosaccharide metabolic process	Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process.	got7fsn_ti	positive regulation of cellooligosaccharide metabolism						tt	2011-08-01T02:26:02Z						biological_process											owl:Class	
GO:1902569	biolink:NamedThing	negative regulation of activation of Janus kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity.	got7fsn_ti	down regulation of tyrosine phosphorylation of JAK2 protein|down-regulation of activation of JAK2 kinase activity|down regulation of activation of JAK2 kinase activity|inhibition of activation of JAK2 kinase activity|down regulation of activation of JAK2 protein|down regulation of activation of JAK1 protein|down regulation of tyrosine phosphorylation of JAK1 protein|downregulation of activation of JAK1 protein|inhibition of tyrosine phosphorylation of JAK2 protein|down-regulation of tyrosine phosphorylation of JAK1 protein|negative regulation of activation of JAK2 kinase activity|downregulation of tyrosine phosphorylation of JAK2 protein|downregulation of activation of JAK2 kinase activity|negative regulation of activation of JAK1 protein|down-regulation of activation of JAK2 protein|negative regulation of activation of JAK2 protein|negative regulation of tyrosine phosphorylation of JAK2 protein|down-regulation of activation of JAK1 kinase activity|down-regulation of activation of JAK1 protein|down regulation of activation of JAK1 kinase activity|downregulation of activation of JAK1 kinase activity|inhibition of activation of JAK1 kinase activity|inhibition of activation of JAK2 protein|down-regulation of tyrosine phosphorylation of JAK2 protein|negative regulation of tyrosine phosphorylation of JAK1 protein|inhibition of activation of JAK1 protein|downregulation of tyrosine phosphorylation of JAK1 protein|inhibition of tyrosine phosphorylation of JAK1 protein						ecu	2013-12-10T16:13:20Z						biological_process											owl:Class	
GO:1903569	biolink:NamedThing	positive regulation of protein localization to ciliary membrane	Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.	got7fsn_ti	upregulation of protein localisation in ciliary membrane|up-regulation of protein localization in ciliary membrane|up regulation of protein localisation to ciliary membrane|activation of protein localization in ciliary membrane|up-regulation of protein localization to ciliary membrane|upregulation of protein localization in ciliary membrane|positive regulation of protein localization in ciliary membrane|positive regulation of protein localisation in ciliary membrane|up regulation of protein localization in ciliary membrane|positive regulation of protein localisation to ciliary membrane|upregulation of protein localization to ciliary membrane|up regulation of protein localisation in ciliary membrane|activation of protein localization to ciliary membrane|up regulation of protein localization to ciliary membrane|activation of protein localisation to ciliary membrane|up-regulation of protein localisation in ciliary membrane|activation of protein localisation in ciliary membrane|up-regulation of protein localisation to ciliary membrane|upregulation of protein localisation to ciliary membrane						krc	2014-10-24T21:33:08Z						biological_process											owl:Class	
GO:0150116	biolink:NamedThing	regulation of cell-substrate junction organization	Any process that modulates the frequency, rate or extent of cell-substrate junction organization.	got7fsn_ti							bc	2019-11-14T12:12:27Z						biological_process											owl:Class	
GO:0051947	biolink:NamedThing	regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.	got7fsn_ti	regulation of GABA uptake during transmission of nerve impulse|regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|regulation of gamma-aminobutyric acid reuptake|regulation of 4-aminobutyrate uptake during transmission of nerve impulse|regulation of 4-aminobutyrate reuptake|regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|regulation of GABA reuptake													biological_process											owl:Class	
GO:0052213	biolink:NamedThing	obsolete interaction with symbiont via secreted substance	OBSOLETE. An interaction with a symbiont organism mediated by a substance secreted by a host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with symbiont via secreted substance involved in symbiotic interaction|interaction with symbiont via secreted substance during symbiotic interaction				The reason for obsoletion is that this process was not clearly defined, and propably represented some immune response. .					True				biological_process											owl:Class	
GO:0140247	biolink:NamedThing	protein catabolic process at presynapse	The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/204			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:23:49Z						biological_process											owl:Class	
GO:0034313	biolink:NamedThing	diol catabolic process	The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.	got7fsn_ti	dihydric alcohol catabolic process|diol degradation|diol breakdown|diol catabolism													biological_process											owl:Class	
GO:0033344	biolink:NamedThing	cholesterol efflux	The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.	got7fsn_ti	cholesterol export													biological_process											owl:Class	
GO:1904277	biolink:NamedThing	negative regulation of wax biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process.	got7fsn_ti	downregulation of wax formation|down regulation of wax anabolism|down regulation of wax formation|down regulation of wax synthesis|inhibition of wax biosynthetic process|down-regulation of wax biosynthesis|down-regulation of wax synthesis|downregulation of wax biosynthesis|inhibition of wax biosynthesis|down-regulation of wax anabolism|down-regulation of wax formation|downregulation of wax synthesis|inhibition of wax synthesis|inhibition of wax formation|negative regulation of wax anabolism|down regulation of wax biosynthesis|downregulation of wax anabolism|negative regulation of wax biosynthesis|inhibition of wax anabolism|negative regulation of wax synthesis|down regulation of wax biosynthetic process|negative regulation of wax formation|downregulation of wax biosynthetic process|down-regulation of wax biosynthetic process						tb	2015-06-03T17:20:13Z						biological_process											owl:Class	
GO:1903418	biolink:NamedThing	protein localization to plasma membrane of cell tip	A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip.	got7fsn_ti	protein localisation to plasma membrane of cell tip|protein localisation in plasma membrane of cell tip|protein localization in plasma membrane of cell tip						mah	2014-09-08T15:08:51Z						biological_process											owl:Class	
GO:0006785	biolink:NamedThing	heme B biosynthetic process	The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.	got7fsn_ti	heme B formation|heme B biosynthesis|protoheme biosynthesis|heme B synthesis|haem B biosynthetic process|heme B anabolism|protoheme biosynthetic process|haem B biosynthesis													biological_process											owl:Class	
GO:0002666	biolink:NamedThing	positive regulation of T cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction.	got7fsn_ti	stimulation of T cell tolerance induction|positive regulation of T-cell tolerance induction|up-regulation of T cell tolerance induction|upregulation of T cell tolerance induction|positive regulation of T lymphocyte tolerance induction|up regulation of T cell tolerance induction|activation of T cell tolerance induction|positive regulation of T-lymphocyte tolerance induction													biological_process											owl:Class	
GO:0032362	biolink:NamedThing	obsolete FAD catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of FAD, the oxidized form of flavin-adenine dinucleotide.	got7fsn_ti	FAD breakdown|FAD catabolism|oxidized flavin adenine dinucleotide catabolic process|FAD degradation				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.					True				biological_process											owl:Class	
GO:0005077	biolink:NamedThing	obsolete MAP-kinase anchoring activity	OBSOLETE. Binds to MAP kinase and anchors it to a particular subcellular location.	got7fsn_ti	MAP-kinase anchoring activity|MAP-kinase anchor protein activity				This term was made obsolete because it represents a combination of process and function information.	GO:0008104|GO:0051019				True				molecular_function											owl:Class	
GO:1990581	biolink:NamedThing	obsolete lysosome lysis	OBSOLETE. The rupture of the lysosomal membrane and loss of contents as a result of osmotic change, G-protein-driven disintegration, or unspecified cause.	got7fsn_ti	lysosome lysis|lysosomal lysis				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-12-10T18:54:00Z		True				biological_process											owl:Class	
GO:0002893	biolink:NamedThing	negative regulation of type II hypersensitivity	Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.	got7fsn_ti	inhibition of type II hypersensitivity|down regulation of type II hypersensitivity|downregulation of type II hypersensitivity|down-regulation of type II hypersensitivity													biological_process											owl:Class	
GO:0051464	biolink:NamedThing	positive regulation of cortisol secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell.	got7fsn_ti	up regulation of cortisol secretion|stimulation of cortisol secretion|upregulation of cortisol secretion|up-regulation of cortisol secretion|activation of cortisol secretion													biological_process											owl:Class	
CL:0000060	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904162	biolink:NamedThing	obsolete 5'-3' exodeoxyribonuclease activity involved in UV-damage excision repair	OBSOLETE. Any 5'-3' exodeoxyribonuclease activity that is involved in UV-damage excision repair.	got7fsn_ti	5'-3' exodeoxyribonuclease activity involved in alternative excision repair|5'-3' exodeoxyribonuclease activity involved in AER|5'-3' exodeoxyribonuclease activity involved in UVDE-dependent excision repair|5'-3' exodeoxyribonuclease activity involved in UVER|5'-3' exodeoxyribonuclease activity involved in UV-damaged DNA endonuclease-dependent excision repair				The reason for obsoletion is that this term represents a biological process within a molecular function.	GO:0070914	mah	2015-04-21T14:53:19Z		True				molecular_function											owl:Class	
GO:1901713	biolink:NamedThing	negative regulation of urea catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process.	got7fsn_ti	negative regulation of urea degradation|down regulation of urea degradation|inhibition of urea catabolic process|inhibition of urea decomposition|down-regulation of urea catabolic process|down-regulation of urea catabolism|inhibition of urea breakdown|down-regulation of urea degradation|down regulation of urea decomposition|downregulation of urea decomposition|down regulation of urea breakdown|inhibition of urea catabolism|downregulation of urea catabolism|down-regulation of urea breakdown|down-regulation of urea decomposition|down regulation of urea catabolic process|downregulation of urea breakdown|negative regulation of urea breakdown|inhibition of urea degradation|down regulation of urea catabolism|downregulation of urea catabolic process|negative regulation of urea decomposition|downregulation of urea degradation|negative regulation of urea catabolism						mcc	2012-12-19T16:12:13Z						biological_process											owl:Class	
GO:0046639	biolink:NamedThing	negative regulation of alpha-beta T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.	got7fsn_ti	negative regulation of alpha-beta T-cell differentiation|down-regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T cell development|negative regulation of alpha-beta T-lymphocyte differentiation|inhibition of alpha-beta T cell differentiation|downregulation of alpha-beta T cell differentiation|down regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0032057	biolink:NamedThing	negative regulation of translational initiation in response to stress	Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.	got7fsn_ti	downregulation of translation initiation in response to stress|inhibition of translation initiation in response to stress|down-regulation of translation initiation in response to stress|down regulation of translation initiation in response to stress													biological_process											owl:Class	
GO:2000170	biolink:NamedThing	positive regulation of peptidyl-cysteine S-nitrosylation	Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.	got7fsn_ti							rl	2010-10-07T10:49:35Z						biological_process											owl:Class	
GO:1905182	biolink:NamedThing	positive regulation of urease activity	Any process that activates or increases the frequency, rate or extent of urease activity.	got7fsn_ti	upregulation of urease activity|activation of urease activity|up regulation of urea amidohydrolase activity|upregulation of urea amidohydrolase activity|activation of urea amidohydrolase activity|positive regulation of urea amidohydrolase activity|up-regulation of urea amidohydrolase activity|up regulation of urease activity|up-regulation of urease activity						tb	2016-05-09T23:16:03Z						biological_process											owl:Class	
GO:0015594	biolink:NamedThing	ABC-type putrescine transporter activity	Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in).	got7fsn_ti	putrescine porter activity|putrescine-importing ATPase activity|ATPase-coupled putrescine transmembrane transporter activity											EC:7.6.2.16|RHEA:29995		molecular_function											owl:Class	
GO:0071571	biolink:NamedThing	obsolete LRR domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an LRR (leucine-rich repeat) domain interaction.	got7fsn_ti	leucine-rich repeat domain-mediated complex assembly				This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-20T04:33:49Z		True				biological_process											owl:Class	
GO:1905958	biolink:NamedThing	negative regulation of cellular response to alcohol	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol.	got7fsn_ti	inhibition of cellular response to alcohol|downregulation of cellular response to alcohol|down regulation of cellular response to alcohol|down-regulation of cellular response to alcohol						hbye	2017-02-22T12:03:08Z						biological_process											owl:Class	
GO:0048215	biolink:NamedThing	positive regulation of Golgi vesicle fusion to target membrane	Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane.	got7fsn_ti	stimulation of Golgi vesicle fusion to target membrane|up regulation of Golgi vesicle fusion to target membrane|up-regulation of Golgi vesicle fusion to target membrane|upregulation of Golgi vesicle fusion to target membrane|activation of Golgi vesicle fusion to target membrane													biological_process											owl:Class	
GO:1904913	biolink:NamedThing	regulation of establishment of protein-containing complex localization to telomere	Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.	got7fsn_ti	regulation of establishment of macromolecular complex localisation to telomere|regulation of establishment of macromolecular complex localization to telomere						rph	2016-01-19T10:38:22Z						biological_process											owl:Class	
GO:0080160	biolink:NamedThing	selenate transport	The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							dhl	2010-09-01T04:17:38Z						biological_process											owl:Class	
GO:1903324	biolink:NamedThing	negative regulation of snoRNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process.	got7fsn_ti	down-regulation of snoRNA metabolic process|down-regulation of snoRNA metabolism|negative regulation of snoRNA metabolism|inhibition of snoRNA metabolic process|down regulation of snoRNA metabolism|downregulation of snoRNA metabolism|down regulation of snoRNA metabolic process|inhibition of snoRNA metabolism|downregulation of snoRNA metabolic process						vw	2014-08-18T13:05:25Z						biological_process											owl:Class	
GO:0090272	biolink:NamedThing	negative regulation of fibroblast growth factor production	Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti							tb	2010-02-05T02:33:33Z						biological_process											owl:Class	
GO:0009200	biolink:NamedThing	deoxyribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	deoxyribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0003733	biolink:NamedThing	obsolete ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ribonucleoprotein			GO:1990904	This term was made obsolete because it describes a cellular component rather than a molecular function.					True				molecular_function											owl:Class	
GO:1901528	biolink:NamedThing	hydrogen peroxide mediated signaling pathway involved in stomatal movement	Any hydrogen peroxide mediated signaling pathway that is involved in stomatal movement.	got7fsn_ti	hydrogen peroxide mediated signalling pathway involved in stomatal movement|H2O2 mediated signaling pathway involved in stomatal movement						tb	2012-10-23T23:15:25Z						biological_process											owl:Class	
GO:1901930	biolink:NamedThing	alpha-copaene catabolic process	The chemical reactions and pathways resulting in the breakdown of alpha-copaene.	got7fsn_ti	alpha-copaene catabolism|alpha-copaene degradation|alpha-copaene breakdown						ms	2013-02-18T14:54:43Z						biological_process											owl:Class	
GO:0032462	biolink:NamedThing	regulation of protein homooligomerization	Any process that modulates the frequency, rate or extent of protein homooligomerization.	got7fsn_ti														biological_process											owl:Class	
GO:0019000	biolink:NamedThing	obsolete endonuclease G activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	endonuclease G activity				This term was made obsolete because it represents a gene product.	GO:0004520|GO:0004521				True				molecular_function											owl:Class	
GO:1904897	biolink:NamedThing	regulation of hepatic stellate cell proliferation	Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.	got7fsn_ti	regulation of Ito cell proliferation|regulation of hepatic perisinusoidal cell proliferation|regulation of perisinusoidal cell proliferation						sl	2016-01-14T15:56:59Z						biological_process											owl:Class	
GO:1900156	biolink:NamedThing	positive regulation of bone trabecula formation	Any process that activates or increases the frequency, rate or extent of bone trabecula formation.	got7fsn_ti	up-regulation of skeletal trabeculation|activation of skeletal trabeculation|activation of skeletal trabecula biogenesis|positive regulation of skeletal trabecula biogenesis|positive regulation of bone trabeculation|upregulation of skeletal trabecula formation|positive regulation of skeletal trabecula formation|positive regulation of skeletal trabeculation|up regulation of skeletal trabecula formation|upregulation of bone trabecula biogenesis|up regulation of bone trabecula formation|activation of skeletal trabecula formation|upregulation of skeletal trabeculation|upregulation of bone trabecula formation|activation of bone trabecula biogenesis|up regulation of bone trabecula biogenesis|activation of bone trabeculation|up-regulation of bone trabecula formation|up-regulation of bone trabeculation|up regulation of skeletal trabecula biogenesis|up-regulation of skeletal trabecula biogenesis|activation of bone trabecula formation|upregulation of skeletal trabecula biogenesis|up regulation of skeletal trabeculation|positive regulation of bone trabecula biogenesis|up regulation of bone trabeculation|upregulation of bone trabeculation|up-regulation of skeletal trabecula formation|up-regulation of bone trabecula biogenesis						vk	2012-03-07T01:47:10Z						biological_process											owl:Class	
GO:0031066	biolink:NamedThing	regulation of histone deacetylation at centromere	Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0010153	biolink:NamedThing	obsolete polar cell elongation	OBSOLETE. Cell expansion that results in an increase in cell size along the axis of an organ in a polarized fashion.	got7fsn_ti	polarity-dependent cell elongation|polar cell elongation				This term was made obsolete because it did not represent a process discrete from its sibling terms.	GO:0042815|GO:0042814				True				biological_process											owl:Class	
GO:2000441	biolink:NamedThing	negative regulation of toll-like receptor 15 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 15 signalling pathway|negative regulation of TLR15 signaling pathway						bf	2011-03-04T10:29:04Z						biological_process											owl:Class	
GO:1903832	biolink:NamedThing	regulation of cellular response to amino acid starvation	Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation.	got7fsn_ti							rn	2015-01-21T18:44:28Z						biological_process											owl:Class	
GO:1900318	biolink:NamedThing	regulation of methane biosynthetic process from dimethylamine	Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine.	got7fsn_ti							tt	2012-04-06T01:43:21Z						biological_process											owl:Class	
GO:0051946	biolink:NamedThing	regulation of glutamate uptake involved in transmission of nerve impulse	Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.	got7fsn_ti	regulation of glutamate reuptake|regulation of glutamate uptake during transmission of nerve impulse|regulation of L-glutamate reuptake|regulation of glutamate uptake involved in conduction of nerve impulse|regulation of L-glutamate uptake during transmission of nerve impulse													biological_process											owl:Class	
PR:000001472	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902465	biolink:NamedThing	negative regulation of histone H3-K27 trimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation.	got7fsn_ti	inhibition of histone H3-K27 trimethylation|down regulation of histone H3-K27 trimethylation|down-regulation of histone H3-K27 trimethylation|downregulation of histone H3-K27 trimethylation						krc	2013-10-22T14:59:04Z						biological_process											owl:Class	
GO:1905007	biolink:NamedThing	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.	got7fsn_ti	activation of epithelial to mesenchymal transition involved in endocardial cushion formation|up-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|up regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|upregulation of epithelial to mesenchymal transition involved in endocardial cushion formation						rl	2016-03-01T15:38:54Z						biological_process											owl:Class	
GO:2001099	biolink:NamedThing	maltotetraose transport	The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:15:03Z						biological_process											owl:Class	
GO:0080053	biolink:NamedThing	response to phenylalanine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:1903552	biolink:NamedThing	negative regulation of extracellular exosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly.	got7fsn_ti	inhibition of extracellular vesicular exosome assembly|down-regulation of extracellular vesicular exosome assembly|negative regulation of extracellular vesicular exosome assembly|downregulation of extracellular vesicular exosome assembly|down regulation of extracellular vesicular exosome assembly						pga	2014-10-20T15:37:33Z						biological_process											owl:Class	
GO:1901614	biolink:NamedThing	positive regulation of terminal button organization	Any process that activates or increases the frequency, rate or extent of terminal button organization.	got7fsn_ti	up regulation of synaptic bouton organization|positive regulation of terminal bouton organization|positive regulation of presynaptic bouton organization|activation of terminal bouton organization|up-regulation of terminal bouton organization|positive regulation of terminal button organisation|activation of presynaptic bouton organization|up regulation of terminal button organization|activation of synaptic bouton organization|up-regulation of synaptic bouton organization|up-regulation of terminal button organisation|up regulation of bouton organization|activation of bouton organization|activation of terminal button organization|up-regulation of presynaptic bouton organization|upregulation of presynaptic bouton organization|positive regulation of bouton organization|upregulation of terminal bouton organization|upregulation of terminal button organization|upregulation of bouton organization|up regulation of terminal bouton organization|up regulation of terminal button organisation|positive regulation of synaptic bouton organization|upregulation of terminal button organisation|up-regulation of bouton organization|activation of terminal button organisation|up-regulation of terminal button organization|upregulation of synaptic bouton organization|up regulation of presynaptic bouton organization						lb	2012-11-13T10:40:58Z						biological_process											owl:Class	
GO:0042064	biolink:NamedThing	obsolete cell adhesion receptor regulator activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cell adhesion receptor regulator activity				This term was made obsolete because it represents a gene product.	GO:0005102|GO:0030155				True				molecular_function											owl:Class	
GO:1901902	biolink:NamedThing	tyrocidine metabolic process	The chemical reactions and pathways involving tyrocidine.	got7fsn_ti	tyrocidine metabolism						yaf	2013-02-12T23:40:29Z						biological_process											owl:Class	
GO:1901162	biolink:NamedThing	primary amino compound biosynthetic process	The chemical reactions and pathways resulting in the formation of primary amino compound.	got7fsn_ti	primary amino compound anabolism|primary amino compound formation|primary amino compound synthesis|primary amino compound biosynthesis						bf	2012-07-18T04:45:14Z						biological_process											owl:Class	
GO:0052434	biolink:NamedThing	obsolete modulation by organism of symbiont cell-mediated immune response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of any form of cell-based immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont cell-mediated immune response|modulation by organism of symbiont cell-based immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0031923	biolink:NamedThing	pyridoxine transport	The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:1902040	biolink:NamedThing	positive regulation of seed dormancy process	Any process that activates or increases the frequency, rate or extent of seed dormancy process.	got7fsn_ti	positive regulation of seed dormancy|upregulation of seed dormancy|activation of seed dormancy process|up regulation of seed dormancy|upregulation of seed dormancy process|up-regulation of seed dormancy|up regulation of seed dormancy process|up-regulation of seed dormancy process|activation of seed dormancy						tb	2013-04-02T22:13:20Z						biological_process											owl:Class	
CHEBI:23453	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008978	biolink:NamedThing	obsolete prepilin peptidase activity	OBSOLETE. Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.	got7fsn_ti	prepilin peptidase activity			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0090010	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in primitive streak formation	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the primitive streak.	got7fsn_ti	TGFbeta signaling pathway involved in primitive streak formation|transforming growth factor beta receptor signalling pathway involved in primitive streak formation						tb	2009-07-29T10:38:40Z						biological_process											owl:Class	
GO:0005698	biolink:NamedThing	obsolete centromere	OBSOLETE. The region of a eukaryotic chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromosome consists of two sister chromatids with a constriction at a point which forms the centromere. During late prophase two kinetochores assemble on each centromere, one kinetochore on each sister chromatid.	got7fsn_ti	centromere				This term was made obsolete because it is a genetically defined region and not a specific subcellular localization.	GO:0000775				True				cellular_component											owl:Class	
GO:1900868	biolink:NamedThing	sarcinapterin biosynthetic process	The chemical reactions and pathways resulting in the formation of sarcinapterin.	got7fsn_ti	sarcinapterin biosynthesis|sarcinapterin anabolism|sarcinapterin formation|sarcinapterin synthesis						tt	2012-06-12T04:34:33Z						biological_process											owl:Class	
GO:0019848	biolink:NamedThing	obsolete conotoxin activity	OBSOLETE. Acts to inhibit neural function in another organism by inhibiting voltage-gated calcium ion channels and neurotransmitter release. This function is thought to be specific to the venom of two marine snail species.	got7fsn_ti	conotoxin activity				This term was made obsolete because it represents a gene product.	GO:0019855|GO:0046929				True				molecular_function											owl:Class	
GO:0016945	biolink:NamedThing	obsolete RNA polymerase III transcription elongation factor activity	OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase III following transcription initiation.	got7fsn_ti	RNA polymerase III transcription elongation factor activity|Pol III transcription elongation factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006385				True				molecular_function											owl:Class	
CHEBI:58596	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031019	biolink:NamedThing	mitochondrial mRNA editing complex	An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.	got7fsn_ti	mitochondrial editosome													cellular_component											owl:Class	
GO:0008549	biolink:NamedThing	obsolete dynamin GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An enzyme that is involved in endocytosis and is instrumental in pinching off membrane vesicles.	got7fsn_ti	dynamin GTPase activity|dynamine GTPase activity			GO:0003924	This term was made obsolete because it represents a gene product.	GO:0006897				True				molecular_function											owl:Class	
GO:1901999	biolink:NamedThing	homogentisate metabolic process	The chemical reactions and pathways involving homogentisate.	got7fsn_ti	homogentisate metabolism						tb	2013-03-21T00:01:02Z						biological_process											owl:Class	
GO:0106198	biolink:NamedThing	obsolete translocase activity acting on inorganic anions linked to a decarboxylation reaction	OBSOLETE. Catalysis of the translocation of an inorganic anion linked to a decarboxylation reaction.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:20:14Z		True		EC:7.3.4.-		molecular_function											owl:Class	
GO:0050426	biolink:NamedThing	obsolete peptidyl-glycinamidase activity	OBSOLETE. Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide.	got7fsn_ti	peptidyl-glycinamidase activity|peptidyl carboxy-amidase activity|peptidyl amino acid amide hydrolase activity|peptidyl carboxyamidase activity|carboxyamidase activity|carboxamidopeptidase activity			GO:0008242	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0005106	biolink:NamedThing	obsolete ephrin	OBSOLETE. A class of proteins that interact with the ephrin receptors.	got7fsn_ti	ephrin				This term was made obsolete because it refers to a class of gene products.	GO:0046875				True				molecular_function											owl:Class	
GO:0009004	biolink:NamedThing	obsolete signal peptidase I activity	OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor.	got7fsn_ti	HOSP|Escherichia coli leader peptidase|prokaryotic signal proteinase|signalase activity|pilin leader peptidase|signal proteinase activity|PuIO prepilin peptidase|leader proteinase activity|prokaryotic signal peptidase|signal peptidase I activity|eukaryotic signal proteinase|phage-procoat-leader peptidase activity|eukaryotic signal peptidase|propeptidase activity|leader peptidase I|bacterial leader peptidase 1|signal peptide hydrolase activity|leader peptidase activity|bacterial leader peptidase I activity|SPase I activity|prokaryotic leader peptidase|leader peptide hydrolase activity|SPC			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1902413	biolink:NamedThing	negative regulation of mitotic cytokinesis	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis.	got7fsn_ti	down-regulation of mitotic cytokinesis|down regulation of mitotic cytokinesis|down-regulation of cytokinesis after mitosis|inhibition of mitotic cytokinesis|downregulation of cytokinesis after mitosis|inhibition of cytokinesis after mitosis|downregulation of mitotic cytokinesis|down regulation of cytokinesis after mitosis|negative regulation of cytokinesis after mitosis						jl	2013-09-12T14:11:59Z						biological_process											owl:Class	
GO:0052698	biolink:NamedThing	ergothioneine metabolic process	The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.	got7fsn_ti	ergothioneine metabolism|2-mercaptoergothioneine trimethylbetaine metabolic process|2-mercaptoergothioneine trimethylbetaine metabolism|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate metabolic process						ai	2011-08-01T03:52:11Z						biological_process											owl:Class	
GO:0009136	biolink:NamedThing	purine nucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine nucleoside diphosphate biosynthesis|purine nucleoside diphosphate formation|purine nucleoside diphosphate synthesis|purine nucleoside diphosphate anabolism													biological_process											owl:Class	
GO:1905092	biolink:NamedThing	response to diosgenin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.	got7fsn_ti							bc	2016-03-31T11:04:28Z						biological_process											owl:Class	
GO:0008167	biolink:NamedThing	obsolete sigma virus replication	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	sigma virus replication			GO:0019079						True				biological_process											owl:Class	
GO:0032764	biolink:NamedThing	negative regulation of mast cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.	got7fsn_ti	inhibition of mast cell cytokine production|down-regulation of mast cell cytokine production|downregulation of mast cell cytokine production|down regulation of mast cell cytokine production													biological_process											owl:Class	
GO:2000250	biolink:NamedThing	negative regulation of actin cytoskeleton reorganization	Any process that stops, prevents, or reduces the frequency, rate or extent of actin cytoskeleton reorganization.	got7fsn_ti	negative regulation of actin cytoskeleton reorganisation|negative regulation of actin cytoskeleton remodeling						vk	2010-11-11T01:25:29Z						biological_process											owl:Class	
GO:1900298	biolink:NamedThing	negative regulation of hexasaccharide transport	Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport.	got7fsn_ti	downregulation of hexasaccharide transport|down regulation of hexasaccharide transport|inhibition of hexasaccharide transport|down-regulation of hexasaccharide transport						tt	2012-04-05T07:44:40Z						biological_process											owl:Class	
GO:1903233	biolink:NamedThing	regulation of calcium ion-dependent exocytosis of neurotransmitter	Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.	got7fsn_ti					An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP)		pad	2014-07-31T11:54:33Z						biological_process											owl:Class	
CHEBI:57692	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902842	biolink:NamedThing	negative regulation of netrin-activated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway.	got7fsn_ti	downregulation of netrin-activated signalling pathway|inhibition of netrin-mediated signaling pathway|negative regulation of netrin-mediated signaling pathway|down-regulation of netrin signaling pathway|downregulation of netrin signaling pathway|inhibition of netrin-activated signal transduction pathway|inhibition of netrin-activated signaling pathway|negative regulation of netrin-activated signalling pathway|down regulation of netrin-activated signalling pathway|down regulation of netrin-activated signaling pathway|negative regulation of netrin-activated signal transduction pathway|downregulation of netrin-activated signaling pathway|down-regulation of netrin-mediated signaling pathway|down regulation of netrin-activated signal transduction pathway|down regulation of netrin signaling pathway|down-regulation of netrin-activated signal transduction pathway|down regulation of netrin-mediated signaling pathway|down-regulation of netrin-activated signaling pathway|downregulation of netrin-activated signal transduction pathway|inhibition of netrin-activated signalling pathway|down-regulation of netrin-activated signalling pathway|downregulation of netrin-mediated signaling pathway|negative regulation of netrin signaling pathway|inhibition of netrin signaling pathway						kmv	2014-04-01T15:25:33Z						biological_process											owl:Class	
GO:0051672	biolink:NamedThing	obsolete catabolism by organism of cell wall peptidoglycan in other organism	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of the cell wall peptidoglycans of another organism.	got7fsn_ti	cell wall peptidoglycan catabolic process in another organism|catabolic process of cell wall peptidoglycans of other organism|catabolism of cell wall peptidoglycans of other organism|cell wall catabolic process in other organism|cell wall catabolism in other organism	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:2000065	biolink:NamedThing	negative regulation of cortisol biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process.	got7fsn_ti	negative regulation of cortisol formation|negative regulation of cortisol anabolism|negative regulation of cortisol biosynthesis|negative regulation of cortisol synthesis						jl	2010-08-20T01:51:23Z						biological_process											owl:Class	
GO:1901426	biolink:NamedThing	response to furfural	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus.	got7fsn_ti							tt	2012-10-01T18:45:43Z						biological_process											owl:Class	
GO:0000255	biolink:NamedThing	allantoin metabolic process	The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism.	got7fsn_ti	allantoin metabolism													biological_process											owl:Class	
IAO:0100001	biolink:NamedThing	term replaced by		got7fsn_ti																									owl:AnnotationProperty	
GO:0015543	biolink:NamedThing	obsolete lactose/glucose efflux transporter activity	OBSOLETE. Catalysis of the reaction: glucose or lactose(in) = glucose or lactose(out).	got7fsn_ti	lactose/glucose efflux transporter activity				This term was made obsolete because it represents two molecular functions.	GO:0015155				True				molecular_function											owl:Class	
GO:0090554	biolink:NamedThing	phosphatidylcholine floppase activity	Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	phosphatidylcholine-translocating ATPase activity|ATPase-coupled phosphatidylcholine transporter activity|phosphatidylcholine floppase activity (cytosolic to exoplasmic leaftlet)|ATP-dependent phosphatidylcholine transporter activity						tb	2013-10-24T16:07:20Z				RHEA:38583		molecular_function											owl:Class	
GO:0075270	biolink:NamedThing	negative regulation of aecium development	Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.	got7fsn_ti														biological_process											owl:Class	
GO:1904143	biolink:NamedThing	positive regulation of carotenoid biosynthetic process	Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process.	got7fsn_ti	activation of carotenoid biosynthetic process|activation of carotenoid biosynthesis|up regulation of carotenoid anabolism|activation of carotenoid anabolism|activation of carotenoid synthesis|upregulation of carotenoid formation|positive regulation of carotenoid biosynthesis|up-regulation of carotenoid formation|positive regulation of carotenoid formation|up-regulation of carotenoid synthesis|activation of carotenoid formation|up-regulation of carotenoid biosynthetic process|positive regulation of carotenoid anabolism|upregulation of carotenoid biosynthetic process|upregulation of carotenoid anabolism|up regulation of carotenoid formation|up regulation of carotenoid synthesis|up regulation of carotenoid biosynthesis|upregulation of carotenoid synthesis|upregulation of carotenoid biosynthesis|positive regulation of carotenoid synthesis|up-regulation of carotenoid anabolism|up regulation of carotenoid biosynthetic process|up-regulation of carotenoid biosynthesis						tb	2015-04-13T19:39:19Z						biological_process											owl:Class	
GO:1905073	biolink:NamedThing	regulation of tight junction disassembly	Any process that modulates the frequency, rate or extent of tight junction disassembly.	got7fsn_ti	regulation of occluding cell junction disassembly|regulation of occluding junction disassembly						rl	2016-03-23T19:32:51Z						biological_process											owl:Class	
GO:0071323	biolink:NamedThing	cellular response to chitin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.	got7fsn_ti							mah	2009-12-10T05:25:54Z						biological_process											owl:Class	
GO:0090109	biolink:NamedThing	regulation of cell-substrate junction assembly	Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.	got7fsn_ti							tb	2009-11-25T11:00:58Z						biological_process											owl:Class	
GO:0000905	biolink:NamedThing	sporocarp development involved in asexual reproduction	The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction.	got7fsn_ti	fruiting body formation involved in asexual reproduction|monokaryotic fruiting|conidium development|homokaryotic fruiting|haploid fruiting|imperfect stage fruiting body development													biological_process											owl:Class	
GO:2001301	biolink:NamedThing	lipoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.	got7fsn_ti	lipoxin formation|lipoxin biosynthesis|lipoxin synthesis|lipoxin anabolism						bf	2012-03-07T11:11:13Z						biological_process											owl:Class	
GO:0140679	biolink:NamedThing	ABC-type sodium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na(in) -> ADP + phosphate + Na(out).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21796					pg	2021-07-08T11:22:56Z				EC:7.2.2.4|TC:3.A.1.115.1|RHEA:14633		molecular_function											owl:Class	
GO:0090051	biolink:NamedThing	negative regulation of cell migration involved in sprouting angiogenesis	Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.	got7fsn_ti							tb	2009-08-07T10:42:00Z						biological_process											owl:Class	
GO:0072723	biolink:NamedThing	cellular response to amitrole	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.	got7fsn_ti	cellular response to 3-amino-1,2,4-triazole						mah	2012-05-31T10:51:52Z						biological_process											owl:Class	
GO:2001177	biolink:NamedThing	negative regulation of mediator complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly.	got7fsn_ti							yaf	2011-11-02T11:22:23Z						biological_process											owl:Class	
GO:1900110	biolink:NamedThing	negative regulation of histone H3-K9 dimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation.	got7fsn_ti	down-regulation of histone H3-K9 dimethylation|downregulation of histone H3-K9 dimethylation|down regulation of histone lysine H3 K9 dimethylation|negative regulation of histone H3 K9 dimethylation|inhibition of histone H3-K9 dimethylation|down-regulation of histone H3 K9 dimethylation|inhibition of histone H3 K9 dimethylation|downregulation of histone H3 K9 dimethylation|negative regulation of histone lysine H3 K9 dimethylation|down regulation of histone H3 K9 dimethylation|down-regulation of histone lysine H3 K9 dimethylation|down regulation of histone H3-K9 dimethylation|downregulation of histone lysine H3 K9 dimethylation|inhibition of histone lysine H3 K9 dimethylation						bf	2012-02-21T09:06:22Z						biological_process											owl:Class	
GO:0019893	biolink:NamedThing	obsolete DNA replication inhibitor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DNA replication inhibitor			GO:0008156	This term was made obsolete because it does not represent a true molecular function.					True				molecular_function											owl:Class	
GO:0008605	biolink:NamedThing	obsolete protein kinase CK2 regulator activity	OBSOLETE. Modulation of the activity of the enzyme protein kinase CK2.	got7fsn_ti	protein kinase CK2 regulator activity|casein kinase II, regulator|protein kinase CK2, intrinsic regulator activity			GO:0019887	This term was made obsolete because it represents a regulator of an obsolete molecular function.					True				molecular_function											owl:Class	
GO:2000717	biolink:NamedThing	positive regulation of maintenance of mitotic sister chromatid cohesion, arms	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.	got7fsn_ti	positive regulation of maintenance of mitotic sister chromatin cohesion along arms|positive regulation of maintenance of sister chromatin cohesion along arms at mitosis						mah	2011-06-03T10:38:35Z						biological_process											owl:Class	
GO:0016092	biolink:NamedThing	prenol catabolic process	The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.	got7fsn_ti	prenol breakdown|prenol degradation|prenol catabolism													biological_process											owl:Class	
GO:0060243	biolink:NamedThing	negative regulation of cell growth involved in contact inhibition	The negative regulation of cell growth in response to increased cell density.	got7fsn_ti														biological_process											owl:Class	
GO:0044135	biolink:NamedThing	obsolete growth of symbiont on or near host phyllosphere	OBSOLETE. The increase in size or mass of symbiont occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18786					jl	2009-08-04T04:11:23Z		True				biological_process											owl:Class	
GO:0048269	biolink:NamedThing	methionine adenosyltransferase complex	A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.	got7fsn_ti	MAT complex													cellular_component											owl:Class	
GO:1900181	biolink:NamedThing	negative regulation of protein localization to nucleus	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.	got7fsn_ti	down regulation of protein localization in nucleus|down regulation of protein localisation to nucleus|negative regulation of protein localization in nucleus|down regulation of protein localization in cell nucleus|downregulation of protein localization in cell nucleus|down-regulation of protein localization in cell nucleus|downregulation of protein localisation to nucleus|negative regulation of protein localization in cell nucleus|down-regulation of protein localization to nucleus|inhibition of protein localization to nucleus|down-regulation of protein localization in nucleus|inhibition of protein localization in nucleus|down-regulation of protein localisation to nucleus|down regulation of protein localization to nucleus|downregulation of protein localization to nucleus|negative regulation of protein localisation to nucleus|downregulation of protein localization in nucleus|inhibition of protein localisation to nucleus|inhibition of protein localization in cell nucleus						bf	2012-03-12T01:23:48Z						biological_process											owl:Class	
GO:0097690	biolink:NamedThing	iron ion transmembrane transporter inhibitor activity	Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter.	got7fsn_ti	iron channel inhibitor activity				An example of this is human hepcidin (UniProt symbol P81172), which regulates iron transport out of cells (see PMID:15514116).									molecular_function											owl:Class	
GO:1901387	biolink:NamedThing	positive regulation of voltage-gated calcium channel activity	Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.	got7fsn_ti	up-regulation of voltage gated calcium channel activity|up-regulation of voltage-gated calcium ion channel activity|upregulation of voltage gated calcium channel activity|up-regulation of voltage-dependent calcium channel activity|up-regulation of voltage-gated calcium channel activity|up regulation of voltage gated calcium channel activity|up regulation of depolarization-activated voltage-gated calcium channel activity|positive regulation of voltage gated calcium channel activity|upregulation of voltage-gated calcium ion channel activity|positive regulation of dihydropyridine-sensitive calcium channel activity|activation of dihydropyridine-sensitive calcium channel activity|positive regulation of voltage-gated calcium ion channel activity|positive regulation of depolarization-activated voltage-gated calcium channel|upregulation of depolarization-activated voltage-gated calcium channel activity|up regulation of depolarization-activated voltage gated calcium channel activity|up-regulation of depolarization-activated voltage-gated calcium channel activity|upregulation of depolarization-activated calcium channel|activation of depolarization-activated voltage gated calcium channel activity|upregulation of dihydropyridine-sensitive calcium channel activity|activation of voltage-sensitive calcium channel|up-regulation of dihydropyridine-sensitive calcium channel activity|activation of voltage-gated calcium channel activity|activation of voltage-dependent calcium channel activity|positive regulation of depolarization-activated voltage gated calcium channel activity|up regulation of depolarization-activated voltage-gated calcium channel|up regulation of voltage-gated calcium ion channel activity|upregulation of depolarization-activated voltage-gated calcium channel|up regulation of voltage-dependent calcium channel activity|up-regulation of depolarization-activated calcium channel|up-regulation of voltage-sensitive calcium channel|upregulation of voltage-dependent calcium channel activity|positive regulation of depolarization-activated calcium channel|activation of depolarization-activated voltage-gated calcium channel|up-regulation of depolarization-activated voltage gated calcium channel activity|upregulation of depolarization-activated voltage gated calcium channel activity|positive regulation of depolarization-activated voltage-gated calcium channel activity|up-regulation of depolarization-activated voltage-gated calcium channel|activation of depolarization-activated calcium channel|up regulation of dihydropyridine-sensitive calcium channel activity|positive regulation of voltage-sensitive calcium channel|upregulation of voltage-gated calcium channel activity|activation of voltage gated calcium channel activity|up regulation of voltage-sensitive calcium channel|positive regulation of voltage-dependent calcium channel activity|up regulation of voltage-gated calcium channel activity|activation of depolarization-activated voltage-gated calcium channel activity|upregulation of voltage-sensitive calcium channel|up regulation of depolarization-activated calcium channel|activation of voltage-gated calcium ion channel activity						vk	2012-10-01T10:35:32Z						biological_process											owl:Class	
GO:0051942	biolink:NamedThing	negative regulation of amino acid uptake involved in synaptic transmission	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.	got7fsn_ti	negative regulation of amino acid neurotransmitter uptake|downregulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid uptake during transmission of nerve impulse|down regulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid neurotransmitter reuptake|down-regulation of amino acid uptake during transmission of nerve impulse|inhibition of amino acid uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0090024	biolink:NamedThing	negative regulation of neutrophil chemotaxis	Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	got7fsn_ti							tb	2009-08-03T10:13:09Z						biological_process											owl:Class	
GO:1903483	biolink:NamedThing	obsolete regulation of maintenance of mitotic actomyosin contractile ring localization	OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.	got7fsn_ti	regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinetic ring anchoring involved in mitotic cell cycle|regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle				The reason for obsoletion is that this term represents a GO-CAM model.		vw	2014-09-23T16:12:19Z		True				biological_process											owl:Class	
GO:0098019	biolink:NamedThing	obsolete virus tail, major subunit	OBSOLETE. The part of the viral tail that comprises the most common subunit type.	got7fsn_ti	major tail protein				The reason for obsoletion is that these are not precise structures: major (most abundant) and minor subunits of viral tails vary in different viruses/phages.		bm	2012-07-19T11:32:55Z		True				cellular_component											owl:Class	
CHEBI:15740	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015387	biolink:NamedThing	potassium:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).	got7fsn_ti	potassium:hydrogen symporter activity											RHEA:28490		molecular_function											owl:Class	
GO:0000264	biolink:NamedThing	obsolete heterotrimeric G-protein GTPase, beta-subunit	OBSOLETE. Subunit of a heterotrimeric G-protein GTPase; associates tightly with the gamma subunit.	got7fsn_ti	heterotrimeric G-protein GTPase, beta-subunit				This term was made obsolete because it does not represent a molecular function.	GO:0003924|GO:0005834				True				molecular_function											owl:Class	
GO:0090365	biolink:NamedThing	regulation of mRNA modification	Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti	regulation of mRNA editing						tb	2010-07-12T11:04:45Z						biological_process											owl:Class	
GO:0046162	biolink:NamedThing	heme C metabolic process	The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f.	got7fsn_ti	heme C metabolism|haem C metabolic process|haem C metabolism													biological_process											owl:Class	
GO:1904935	biolink:NamedThing	positive regulation of cell proliferation in midbrain	Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain.	got7fsn_ti	positive regulation of mesencepahalic cell proliferation|up-regulation of cell proliferation in midbrain|activation of mesencepahalic cell proliferation|up regulation of cell proliferation in mesencephalon|up-regulation of cell proliferation in mesencephalon|activation of cell proliferation in mesencephalon|upregulation of mesencepahalic cell proliferation|positive regulation of cell proliferation in mesencephalon|upregulation of cell proliferation in midbrain|up regulation of mesencepahalic cell proliferation|up-regulation of mesencepahalic cell proliferation|up regulation of cell proliferation in midbrain|upregulation of cell proliferation in mesencephalon|activation of cell proliferation in midbrain						bf	2016-02-01T13:16:27Z						biological_process											owl:Class	
GO:0019674	biolink:NamedThing	NAD metabolic process	The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.	got7fsn_ti	NAD (oxidized) metabolic process|nicotinamide adenine dinucleotide metabolism|oxidized nicotinamide adenine dinucleotide metabolic process|NAD phosphorylation and dephosphorylation|oxidized NAD metabolism|oxidized nicotinamide adenine dinucleotide metabolism|oxidized NAD metabolic process|nicotinamide adenine dinucleotide metabolic process|NAD metabolism|NAD (oxidized) metabolism													biological_process											owl:Class	
GO:1905176	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell dedifferentiation	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.	got7fsn_ti	activation of vascular smooth muscle cell dedifferentiation|positive regulation of vascular smooth muscle cell dedifferentiation|up regulation of vascular smooth muscle cell dedifferentiation|up-regulation of vascular smooth muscle cell dedifferentiation|upregulation of vascular smooth muscle cell dedifferentiation						rph	2016-05-03T12:32:13Z						biological_process											owl:Class	
GO:1902608	biolink:NamedThing	positive regulation of large conductance calcium-activated potassium channel activity	Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity.	got7fsn_ti	up-regulation of BK calcium-activated potassium channel activity|activation of BK channel activity|positive regulation of BK channel activity|upregulation of large conductance KCa channels|up-regulation of BK channel activity|positive regulation of large conductance KCa channels|up regulation of BK KCa channels|up regulation of BK calcium-activated potassium channel activity|up regulation of large conductance KCa channels|up regulation of BK channel activity|up-regulation of BK KCa channels|up-regulation of large conductance calcium-activated potassium channel activity|positive regulation of BK calcium-activated potassium channel activity|activation of BK calcium-activated potassium channel activity|positive regulation of BK KCa channels|up regulation of large conductance calcium-activated potassium channel activity|upregulation of large conductance calcium-activated potassium channel activity|upregulation of BK channel activity|up-regulation of large conductance KCa channels|upregulation of BK KCa channels|upregulation of BK calcium-activated potassium channel activity|activation of large conductance KCa channels|activation of BK KCa channels|activation of large conductance calcium-activated potassium channel activity						sl	2014-01-02T18:51:21Z						biological_process											owl:Class	
GO:0006232	biolink:NamedThing	TDP biosynthetic process	The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate.	got7fsn_ti	TDP anabolism|TDP biosynthesis|TDP synthesis|TDP formation													biological_process											owl:Class	
GO:0052030	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000210	biolink:NamedThing	positive regulation of anoikis	Any process that activates or increases the frequency, rate or extent of anoikis.	got7fsn_ti	positive regulation of detachment induced cell death|positive regulation of suspension induced apoptosis						mah	2010-11-03T02:00:36Z						biological_process											owl:Class	
GO:0008529	biolink:NamedThing	obsolete endogenous peptide receptor activity	OBSOLETE. Combining with an intracellular peptide to initiate a change in cell activity.	got7fsn_ti	endogenous peptide receptor activity				This term was made obsolete because it contains both component and function information.	GO:0005622|GO:0001653				True				molecular_function											owl:Class	
GO:1902250	biolink:NamedThing	regulation of erythrocyte apoptotic process	Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.	got7fsn_ti	regulation of RBC apoptosis|regulation of RBC apoptotic process|regulation of erythrocyte apoptosis|regulation of red blood cell apoptotic process|regulation of red blood cell apoptosis						rl	2013-06-20T19:30:53Z						biological_process											owl:Class	
GO:1900219	biolink:NamedThing	positive regulation of apoptotic process involved in metanephric nephron tubule development	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.	got7fsn_ti	up regulation of apoptotic programmed cell death of metanephric nephron tubule development|positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|up-regulation of apoptosis of metanephric nephron tubule development|up regulation of type I programmed cell death of metanephric nephron tubule development|upregulation of apoptotic cell death of metanephric nephron tubule development|upregulation of apoptotic program of metanephric nephron tubule development|up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development|activation of type I programmed cell death of metanephric nephron tubule development|activation of apoptotic cell death of metanephric nephron tubule development|up regulation of apoptotic cell death of metanephric nephron tubule development|upregulation of apoptotic process involved in metanephric nephron tubule development|up-regulation of type I programmed cell death of metanephric nephron tubule development|upregulation of apoptotic process of metanephric nephron tubule development|activation of apoptotic program of metanephric nephron tubule development|up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development|up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|positive regulation of apoptosis of metanephric nephron tubule development|activation of signaling (initiator) caspase activity of metanephric nephron tubule development|upregulation of type I programmed cell death of metanephric nephron tubule development|activation of programmed cell death by apoptosis of metanephric nephron tubule development|activation of apoptotic process involved in metanephric nephron tubule development|up-regulation of apoptotic programmed cell death of metanephric nephron tubule development|up regulation of apoptotic process of metanephric nephron tubule development|up-regulation of apoptotic cell death of metanephric nephron tubule development|upregulation of apoptotic programmed cell death of metanephric nephron tubule development|up regulation of programmed cell death by apoptosis of metanephric nephron tubule development|up-regulation of apoptotic process involved in metanephric nephron tubule development|positive regulation of apoptotic programmed cell death of metanephric nephron tubule development|positive regulation of apoptotic program of metanephric nephron tubule development|positive regulation of type I programmed cell death of metanephric nephron tubule development|activation of apoptotic process of metanephric nephron tubule development|activation of apoptosis of metanephric nephron tubule development|positive regulation of apoptotic process of metanephric nephron tubule development|upregulation of programmed cell death by apoptosis of metanephric nephron tubule development|up regulation of apoptotic process involved in metanephric nephron tubule development|up regulation of apoptotic program of metanephric nephron tubule development|up-regulation of apoptotic program of metanephric nephron tubule development|upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development|activation of apoptotic programmed cell death of metanephric nephron tubule development|upregulation of apoptosis of metanephric nephron tubule development|up-regulation of apoptotic process of metanephric nephron tubule development|positive regulation of apoptotic cell death of metanephric nephron tubule development|up regulation of apoptosis of metanephric nephron tubule development						yaf	2012-03-22T10:54:09Z						biological_process											owl:Class	
GO:1903509	biolink:NamedThing	liposaccharide metabolic process	The chemical reactions and pathways involving liposaccharide.	got7fsn_ti	liposaccharide metabolism						dph	2014-10-01T21:52:52Z						biological_process											owl:Class	
GO:0030618	biolink:NamedThing	obsolete transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	OBSOLETE. A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription.	got7fsn_ti	pathway-specific SMAD protein|pathway-restricted SMAD protein|TGFbeta receptor, pathway-specific cytoplasmic mediator activity|receptor-regulated SMAD protein|TGF-beta receptor, pathway-specific cytoplasmic mediator activity|pathway restricted SMAD protein|receptor regulated SMAD protein	https://github.com/geneontology/go-ontology/issues/16202			This term was obsoleted because it is redundant with other terms.	GO:0003712|GO:0000981				True				molecular_function											owl:Class	
GO:1900748	biolink:NamedThing	positive regulation of vascular endothelial growth factor signaling pathway	Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway.	got7fsn_ti	activation of VEGF-activated signaling pathway|up regulation of vascular endothelial growth factor signalling pathway|positive regulation of vascular endothelial growth factor signalling pathway|activation of VEGF signaling|up-regulation of VEGF signaling|up regulation of VEGF-activated signaling pathway|positive regulation of VEGF signaling|up-regulation of VEGF-activated signaling pathway|up-regulation of vascular endothelial growth factor signalling pathway|positive regulation of VEGF-activated signaling pathway|upregulation of VEGF signaling|up regulation of VEGF signaling|activation of vascular endothelial growth factor signaling pathway|upregulation of vascular endothelial growth factor signalling pathway|upregulation of vascular endothelial growth factor signaling pathway|activation of vascular endothelial growth factor signalling pathway|up-regulation of vascular endothelial growth factor signaling pathway|up regulation of vascular endothelial growth factor signaling pathway|upregulation of VEGF-activated signaling pathway						pm	2012-05-29T08:28:36Z						biological_process											owl:Class	
GO:0043537	biolink:NamedThing	negative regulation of blood vessel endothelial cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.	got7fsn_ti	downregulation of blood vessel endothelial cell migration|inhibition of blood vessel endothelial cell migration|down-regulation of blood vessel endothelial cell migration|down regulation of blood vessel endothelial cell migration													biological_process											owl:Class	
GO:0062194	biolink:NamedThing	cytoplasmic microtubule minus-end	A microtubule minus end that is part of a cytoplasmic microtubule.	got7fsn_ti							dph	2019-12-09T19:06:36Z						cellular_component											owl:Class	
GO:1900852	biolink:NamedThing	regulation of terrequinone A biosynthetic process	Any process that modulates the frequency, rate or extent of terrequinone A biosynthetic process.	got7fsn_ti	regulation of terrequinone A formation|regulation of terrequinone A synthesis|regulation of terrequinone A anabolism|regulation of terrequinone A biosynthesis						di	2012-06-07T09:47:09Z						biological_process											owl:Class	
GO:0019570	biolink:NamedThing	L-arabinose catabolic process to 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate.	got7fsn_ti	L-arabinose catabolic process to alpha-ketoglutarate|L-arabinose catabolic process to 2-ketoglutarate|L-arabinose catabolism to alpha-ketoglutarate|L-arabinose catabolism to 2-ketoglutarate|L-arabinose breakdown to 2-oxoglutarate|L-arabinose catabolism to alpha-oxoglutarate|L-arabinose catabolic process to alpha-oxoglutarate|L-arabinose degradation to 2-oxoglutarate													biological_process											owl:Class	
GO:1904104	biolink:NamedThing	negative regulation of convergent extension involved in gastrulation	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation.	got7fsn_ti	downregulation of convergent extension involved in gastrulation|inhibition of convergent extension involved in gastrulation|down-regulation of convergent extension involved in gastrulation|down regulation of convergent extension involved in gastrulation						dph	2015-04-01T11:17:12Z						biological_process											owl:Class	
GO:0009211	biolink:NamedThing	pyrimidine deoxyribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:1901187	biolink:NamedThing	regulation of ephrin receptor signaling pathway	Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway.	got7fsn_ti	regulation of Eph receptor signalling pathway|regulation of Eph receptor signaling pathway						rl	2012-07-24T07:41:49Z						biological_process											owl:Class	
GO:0062195	biolink:NamedThing	microtubule bundle maintenance	The organization process that preserves a microtubule bundle in a stable functional or structural state.	got7fsn_ti							dph	2019-12-09T19:10:30Z						biological_process											owl:Class	
GO:1905096	biolink:NamedThing	positive regulation of apolipoprotein A-I-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.	got7fsn_ti	activation of apolipoprotein A-I-mediated signaling pathway|up-regulation of apolipoprotein A-I-mediated signaling pathway|positive regulation of apolipoprotein A-I-mediated signalling pathway|upregulation of apolipoprotein A-I-mediated signalling pathway|activation of apolipoprotein A-I-mediated signalling pathway|upregulation of apolipoprotein A-I-mediated signaling pathway|up-regulation of apolipoprotein A-I-mediated signalling pathway|up regulation of apolipoprotein A-I-mediated signalling pathway|up regulation of apolipoprotein A-I-mediated signaling pathway						bc	2016-03-31T11:34:07Z						biological_process											owl:Class	
GO:0052415	biolink:NamedThing	obsolete metabolism by organism of glucan in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism by organism of glucan in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0046052	biolink:NamedThing	UTP catabolic process	The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate.	got7fsn_ti	UTP breakdown|UTP degradation|UTP catabolism|UTP hydrolysis													biological_process											owl:Class	
GO:0019345	biolink:NamedThing	cysteine biosynthetic process via S-sulfo-L-cysteine	The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.	got7fsn_ti	cysteine biosynthetic process via S-sulpho-L-cysteine|cysteine synthesis via S-sulfo-L-cysteine|cysteine biosynthesis via S-sulpho-L-cysteine|cysteine formation via S-sulfo-L-cysteine|cysteine anabolism via S-sulfo-L-cysteine													biological_process											owl:Class	
GO:0048776	biolink:NamedThing	negative regulation of leucophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation.	got7fsn_ti	downregulation of leucophore differentiation|down-regulation of leucophore differentiation|inhibition of leucophore differentiation|down regulation of leucophore differentiation													biological_process											owl:Class	
GO:0120292	biolink:NamedThing	positive regulation of mitotic recombination-dependent replication fork processing	Any process that activates or increases the frequency, rate or extent of replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.	got7fsn_ti	positive regulation of recombination-dependent DNA replication|positive regulation of homologous recombination-dependent replication fork processing|positive regulation of homologous recombination dependent replication fork recovery						krc	2021-01-06T19:09:21Z						biological_process											owl:Class	
GO:0052446	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont cell wall thickening	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont cell wall thickening|modulation by organism of symbiont defensive cell wall thickening				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1902622	biolink:NamedThing	regulation of neutrophil migration	Any process that modulates the frequency, rate or extent of neutrophil migration.	got7fsn_ti							sl	2014-01-15T18:58:39Z						biological_process											owl:Class	
CHEBI:33384	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000771	biolink:NamedThing	positive regulation of establishment or maintenance of cell polarity regulating cell shape	Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.	got7fsn_ti							mah	2011-06-22T01:56:55Z						biological_process											owl:Class	
GO:0070378	biolink:NamedThing	positive regulation of ERK5 cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.	got7fsn_ti	activation of BMK cascade|positive regulation of ERK5 signaling pathway|positive regulation of MAPK7 cascade|upregulation of BMK cascade|up regulation of BMK cascade|up-regulation of BMK cascade|positive regulation of BMK cascade|positive regulation of BMK1 cascade|positive regulation of BMK signalling pathway|stimulation of BMK cascade|positive regulation of BMK signaling pathway													biological_process											owl:Class	
GO:2000086	biolink:NamedThing	positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.	got7fsn_ti	positive regulation of mesonephric mesenchyme to epithelial transition						dph	2010-09-03T06:08:24Z						biological_process											owl:Class	
GO:1900507	biolink:NamedThing	negative regulation of iron-sulfur-molybdenum cofactor assembly	Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.	got7fsn_ti	downregulation of iron molybdenum cofactor assembly|downregulation of FeMoco assembly|down-regulation of iron molybdenum cofactor assembly|down-regulation of iron-sulfur-molybdenum cofactor assembly|down-regulation of iron molybdenum cofactor biosynthesis|negative regulation of iron molybdenum cofactor biosynthesis|downregulation of FeMoco biosynthetic process|down regulation of iron molybdenum cofactor assembly|negative regulation of FeMoco biosynthetic process|down-regulation of iron molybdenum cofactor biosynthetic process|negative regulation of iron molybdenum cofactor assembly|inhibition of FeMoco biosynthetic process|inhibition of iron molybdenum cofactor biosynthesis|downregulation of iron molybdenum cofactor biosynthetic process|down regulation of FeMoco assembly|down regulation of FeMoco biosynthetic process|inhibition of iron-sulfur-molybdenum cofactor assembly|negative regulation of FeMoco assembly|downregulation of iron molybdenum cofactor biosynthesis|down-regulation of FeMoco assembly|down regulation of iron-sulfur-molybdenum cofactor assembly|down-regulation of FeMoco biosynthetic process|down regulation of iron molybdenum cofactor biosynthetic process|negative regulation of iron molybdenum cofactor biosynthetic process|inhibition of iron molybdenum cofactor assembly|inhibition of FeMoco assembly|inhibition of iron molybdenum cofactor biosynthetic process|down regulation of iron molybdenum cofactor biosynthesis|downregulation of iron-sulfur-molybdenum cofactor assembly						tt	2012-05-02T04:02:27Z						biological_process											owl:Class	
CHEBI:58641	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000333	biolink:NamedThing	negative regulation of blood microparticle formation	Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation.	got7fsn_ti	negative regulation of microparticle generation|negative regulation of microparticle release						mah	2011-01-31T11:18:18Z						biological_process											owl:Class	
GO:1902923	biolink:NamedThing	poly(3-hydroxyvalerate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate).	got7fsn_ti	poly(3-hydroxyvalerate) biosynthesis|poly(3-hydroxyvalerate) formation|poly(3-hydroxyvalerate) synthesis|poly(3-hydroxyvalerate) anabolism						tt	2014-04-21T19:14:02Z						biological_process											owl:Class	
GO:2000398	biolink:NamedThing	regulation of thymocyte aggregation	Any process that modulates the frequency, rate or extent of thymocyte aggregation.	got7fsn_ti	regulation of T cell precursor aggregation|regulation of immature T-lymphocyte aggregation|regulation of immature T cell aggregation|regulation of thymic lymphocyte aggregation|regulation of immature T-cell aggregation						mah	2011-02-22T02:49:19Z						biological_process											owl:Class	
GO:0008592	biolink:NamedThing	regulation of Toll signaling pathway	Any process that modulates the frequency, rate or extent of the Tl signaling pathway.	got7fsn_ti	regulation of Tl signaling pathway|regulation of Tl signalling pathway|regulation of Toll signalling pathway													biological_process											owl:Class	
CHEBI:26561	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015960	biolink:NamedThing	diadenosine polyphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.	got7fsn_ti	diadenosine polyphosphate formation|diadenosine polyphosphate anabolism|diadenosine polyphosphate synthesis|diadenosine polyphosphate biosynthesis													biological_process											owl:Class	
GO:0060311	biolink:NamedThing	negative regulation of elastin catabolic process	Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.	got7fsn_ti	negative regulation of elastin degradation|negative regulation of elastin catabolism|negative regulation of elastin breakdown|down-regulation of elastin catabolic process													biological_process											owl:Class	
GO:1905522	biolink:NamedThing	negative regulation of macrophage migration	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration.	got7fsn_ti	inhibition of macrophage migration|down-regulation of macrophage migration|down regulation of macrophage migration|downregulation of macrophage migration						sl	2016-10-03T15:29:14Z						biological_process											owl:Class	
GO:0046133	biolink:NamedThing	pyrimidine ribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	pyrimidine ribonucleoside breakdown|pyrimidine ribonucleoside catabolism|pyrimidine ribonucleoside degradation													biological_process											owl:Class	
GO:0051198	biolink:NamedThing	obsolete negative regulation of coenzyme metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.	got7fsn_ti	inhibition of coenzyme metabolic process|negative regulation of coenzyme metabolism|downregulation of coenzyme metabolic process|negative regulation of coenzyme and prosthetic group metabolism|down regulation of coenzyme metabolic process|down-regulation of coenzyme metabolic process|negative regulation of coenzyme and prosthetic group metabolic process				1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True				biological_process											owl:Class	
GO:0016306	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase activity, class III	OBSOLETE. A phosphoinositide 3-kinase which can only phosphorylate phosphatidylinositol.	got7fsn_ti	phosphatidylinositol 3-kinase activity, class III			GO:0016303	This term was made obsolete because it represents a class of gene products.					True				molecular_function											owl:Class	
GO:1902081	biolink:NamedThing	negative regulation of calcium ion import into sarcoplasmic reticulum	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.	got7fsn_ti	inhibition of calcium ion import into sarcoplasmic reticulum|downregulation of calcium ion import into sarcoplasmic reticulum|down regulation of calcium ion import into sarcoplasmic reticulum|down-regulation of calcium ion import into sarcoplasmic reticulum						rl	2013-04-24T16:07:59Z						biological_process											owl:Class	
GO:1905062	biolink:NamedThing	positive regulation of cardioblast proliferation	Any process that activates or increases the frequency, rate or extent of cardioblast proliferation.	got7fsn_ti	up-regulation of cardioblast proliferation|upregulation of cardioblast proliferation|up regulation of cardioblast proliferation|activation of cardioblast proliferation						bc	2016-03-21T11:00:23Z						biological_process											owl:Class	
GO:1902141	biolink:NamedThing	cellular response to inositol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.	got7fsn_ti							al	2013-05-21T13:42:15Z						biological_process											owl:Class	
GO:1905109	biolink:NamedThing	regulation of pulmonary blood vessel remodeling	Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling.	got7fsn_ti							bc	2016-04-06T13:07:24Z						biological_process											owl:Class	
GO:0015060	biolink:NamedThing	obsolete green-sensitive opsin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	green-sensitive opsin				This term was made obsolete because it refers to a class of proteins.	GO:0009881|GO:0046876|GO:0007603|GO:0016021|GO:0016918				True				molecular_function											owl:Class	
GO:0070271	biolink:NamedThing	obsolete protein complex biogenesis	OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex.	got7fsn_ti	protein complex biogenesis and assembly									True				biological_process											owl:Class	
GO:1903082	biolink:NamedThing	positive regulation of C-C chemokine receptor CCR7 signaling pathway	Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.	got7fsn_ti	upregulation of C-C chemokine receptor CCR7 signaling pathway|up regulation of C-C chemokine receptor CCR7 signaling pathway|up-regulation of C-C chemokine receptor CCR7 signalling pathway|up-regulation of C-C chemokine receptor CCR7 signaling pathway|positive regulation of CCR7 signaling pathway|up regulation of C-C chemokine receptor CCR7 signalling pathway|activation of C-C chemokine receptor CCR7 signalling pathway|up-regulation of CCR7 signaling pathway|activation of C-C chemokine receptor CCR7 signaling pathway|activation of CCR7 signaling pathway|upregulation of CCR7 signaling pathway|up regulation of CCR7 signaling pathway|positive regulation of C-C chemokine receptor CCR7 signalling pathway|upregulation of C-C chemokine receptor CCR7 signalling pathway						rl	2014-05-29T18:33:01Z						biological_process											owl:Class	
GO:1905754	biolink:NamedThing	ascospore-type prospore nucleus	Any nucleus that is part of a ascospore-type prospore.	got7fsn_ti	cell nucleus of ascospore-type prospore|nucleus of ascospore-type prospore						al	2016-12-12T13:25:00Z						cellular_component											owl:Class	
GO:0140076	biolink:NamedThing	negative regulation of lipoprotein transport	Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport.	got7fsn_ti							pg	2017-07-21T15:39:50Z						biological_process											owl:Class	
GO:2000223	biolink:NamedThing	regulation of BMP signaling pathway involved in heart jogging	Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in heart jogging.	got7fsn_ti	regulation of BMP signalling pathway involved in heart jogging pathway involved in somitogenesis						vk	2010-11-04T02:44:01Z						biological_process											owl:Class	
GO:0072291	biolink:NamedThing	epithelial cell migration involved in metanephric distal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.	got7fsn_ti							mah	2010-04-09T03:53:37Z						biological_process											owl:Class	
GO:0030181	biolink:NamedThing	obsolete sodium:calcium exchange	OBSOLETE. Exchange diffusion sodium and calcium ions in which influx of sodium ions to the cytosol drives the efflux of calcium ions from the cell.	got7fsn_ti	sodium:calcium exchange				This term was made obsolete because it represents a function rather than a process.	GO:0006814|GO:0005432|GO:0006816				True				biological_process											owl:Class	
GO:1900364	biolink:NamedThing	negative regulation of mRNA polyadenylation	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation.	got7fsn_ti	down-regulation of mRNA polyadenylylation|inhibition of cleavage and polyadenylylation specificity factor activity|inhibition of mRNA polyadenylation|down regulation of mRNA polyadenylylation|down-regulation of cleavage and polyadenylylation specificity factor activity|down-regulation of mRNA polyadenylation|downregulation of mRNA polyadenylylation|negative regulation of mRNA polyadenylylation|downregulation of mRNA polyadenylation|downregulation of cleavage and polyadenylylation specificity factor activity|negative regulation of cleavage and polyadenylylation specificity factor activity|down regulation of cleavage and polyadenylylation specificity factor activity|down regulation of mRNA polyadenylation|inhibition of mRNA polyadenylylation						pr	2012-04-12T04:36:31Z						biological_process											owl:Class	
GO:0046249	biolink:NamedThing	alpha-pinene catabolic process	The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.	got7fsn_ti	alpha-pinene degradation|alpha-pinene catabolism|alpha-pinene breakdown													biological_process											owl:Class	
GO:0110108	biolink:NamedThing	positive regulation of imaginal disc-derived wing vein specification	Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification.	got7fsn_ti							kmv	2018-07-05T13:52:31Z						biological_process											owl:Class	
GO:0005188	biolink:NamedThing	obsolete larval serum protein (sensu Insecta)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	arylphorin|larval serum protein (sensu Insecta)				This term was made obsolete because it describes presence in body fluids rather than an activity.					True				molecular_function											owl:Class	
GO:0072336	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	got7fsn_ti	negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|negative regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|negative regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation|negative regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation						mah	2010-11-03T03:16:10Z						biological_process											owl:Class	
GO:1901404	biolink:NamedThing	regulation of tetrapyrrole catabolic process	Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process.	got7fsn_ti	regulation of tetrapyrrole degradation|regulation of tetrapyrrole catabolism|regulation of tetrapyrrole breakdown						tt	2012-10-01T14:38:12Z						biological_process											owl:Class	
GO:1900901	biolink:NamedThing	positive regulation of heptadecane metabolic process	Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process.	got7fsn_ti	activation of heptadecane metabolism|activation of heptadecane metabolic process|positive regulation of heptadecane metabolism|upregulation of heptadecane metabolism|upregulation of heptadecane metabolic process|up regulation of heptadecane metabolic process|up-regulation of heptadecane metabolism|up-regulation of heptadecane metabolic process|up regulation of heptadecane metabolism						tt	2012-06-13T03:30:33Z						biological_process											owl:Class	
GO:0019312	biolink:NamedThing	L-sorbose metabolic process	The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.	got7fsn_ti	L-sorbose metabolism											MetaCyc:P302-PWY		biological_process											owl:Class	
GO:0050424	biolink:NamedThing	obsolete alanine carboxypeptidase activity	OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups.	got7fsn_ti	alanine carboxypeptidase activity|N-benzoyl-L-alanine-amidohydrolase activity			GO:0004181	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0046120	biolink:NamedThing	deoxyribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	deoxyribonucleoside anabolism|deoxyribonucleoside formation|deoxyribonucleoside synthesis|deoxyribonucleoside biosynthesis													biological_process											owl:Class	
GO:0010667	biolink:NamedThing	negative regulation of cardiac muscle cell apoptotic process	Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	got7fsn_ti	negative regulation of cardiac muscle cell apoptosis|inhibition of cardiac muscle cell apoptosis|down regulation of cardiac muscle cell apoptosis|down-regulation of cardiac muscle cell apoptosis|downregulation of cardiac muscle cell apoptosis													biological_process											owl:Class	
GO:0046498	biolink:NamedThing	S-adenosylhomocysteine metabolic process	The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.	got7fsn_ti	S-adenosylhomocysteine metabolism													biological_process											owl:Class	
GO:0051705	biolink:NamedThing	obsolete multi-organism behavior	OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species.	got7fsn_ti	behavioral signaling|behavioural interaction with other organism|behavioral signalling|behavioral interaction with other organism|behavioural interaction between organisms|behavioral interaction between organisms	https://github.com/geneontology/go-ontology/issues/18810			This term was obsoleted because it was an unnecessary grouping term.					True				biological_process											owl:Class	
GO:0016031	biolink:NamedThing	tRNA import into mitochondrion	The process in which a tRNA is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti	mitochondrial import of cytoplasmic tRNA|cytoplasmic tRNA import into mitochondrion|cytoplasmic tRNA, mitochondrial import|nuclear-encoded tRNA import into mitochondrion|cytoplasmic tRNA transport into mitochondrion|cytoplasmic tRNA import into mitochondria													biological_process											owl:Class	
GO:0043393	biolink:NamedThing	regulation of protein binding	Any process that modulates the frequency, rate or extent of protein binding.	got7fsn_ti														biological_process											owl:Class	
GO:0140347	biolink:NamedThing	N-retinylidene-phosphatidylethanolamine flippase activity	Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	N-retinylidene-phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet)						pg	2019-05-16T13:44:51Z						molecular_function											owl:Class	
GO:1990977	biolink:NamedThing	obsolete negative regulation of mitotic DNA replication initiation from late origin	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2016-07-11T14:56:38Z		True				biological_process											owl:Class	
GO:1901638	biolink:NamedThing	obsolete copper ion import into ascospore-type prospore	OBSOLETE. Any copper ion import that takes place in ascospore-type prospore.	got7fsn_ti	copper ion uptake in ascospore-type prospore|copper ion import into ascospore-type prospore				https://sourceforge.net/tracker/index.php?func=detail&aid=3510080&group_id=36855&atid=440764		al	2012-11-15T15:44:04Z		True				biological_process											owl:Class	
UBERON:0002422	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904698	biolink:NamedThing	negative regulation of acinar cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation.	got7fsn_ti	downregulation of acinic cell proliferation|down regulation of acinic cell proliferation|down regulation of acinous cell proliferation|inhibition of acinar cell proliferation|negative regulation of acinous cell proliferation|inhibition of acinic cell proliferation|down-regulation of acinous cell proliferation|down-regulation of acinic cell proliferation|down regulation of acinar cell proliferation|inhibition of acinous cell proliferation|negative regulation of acinic cell proliferation|downregulation of acinar cell proliferation|down-regulation of acinar cell proliferation|downregulation of acinous cell proliferation						sl	2015-09-30T15:19:57Z						biological_process											owl:Class	
GO:0051642	biolink:NamedThing	centrosome localization	Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti	centrosome localisation|establishment and maintenance of centrosome localization													biological_process											owl:Class	
GO:1904754	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell migration	Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.	got7fsn_ti	up regulation of vascular smooth muscle cell migration|up regulation of vascular associated smooth muscle cell migration|activation of vascular smooth muscle cell migration|upregulation of vascular smooth muscle cell migration|up-regulation of vascular smooth muscle cell migration|up-regulation of vascular associated smooth muscle cell migration|positive regulation of vascular smooth muscle cell migration|activation of vascular associated smooth muscle cell migration|upregulation of vascular associated smooth muscle cell migration						rph	2015-10-19T15:50:05Z						biological_process											owl:Class	
GO:1990293	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005514	biolink:NamedThing	obsolete calcium ion storage activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	calcium ion storage activity				This term was made obsolete because it represents a biological process.	GO:0005509|GO:0051208				True				molecular_function											owl:Class	
GO:0051351	biolink:NamedThing	positive regulation of ligase activity	Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.	got7fsn_ti	up-regulation of ligase activity|activation of ligase activity|stimulation of ligase activity|up regulation of ligase activity|upregulation of ligase activity|ligase activator													biological_process											owl:Class	
GO:0140598	biolink:NamedThing	lipoprotein carrier activity	Binding to and carrying a lipoprotein between two different cellular locations by moving along with the target lipoprotein.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15917					pg	2021-02-10T06:16:26Z						molecular_function											owl:Class	
GO:1900386	biolink:NamedThing	positive regulation of flavonol biosynthetic process	Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process.	got7fsn_ti	upregulation of flavonol biosynthetic process|activation of flavonol biosynthetic process|up regulation of flavonol biosynthetic process|up-regulation of flavonol biosynthetic process						tb	2012-04-17T10:23:09Z						biological_process											owl:Class	
GO:1905009	biolink:NamedThing	negative regulation of L-lysine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell.	got7fsn_ti	down regulation of L-lysine import into cell|downregulation of L-lysine import into cell|negative regulation of lysine uptake|inhibition of L-lysine import into cell|negative regulation of lysine import|negative regulation of L-lysine import into cell|down-regulation of L-lysine import into cell						sl	2016-03-02T00:15:57Z			GO:0010806			biological_process											owl:Class	
CHEBI:18917	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010292	biolink:NamedThing	GTP:GDP antiporter activity	Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out).	got7fsn_ti														molecular_function											owl:Class	
GO:0045981	biolink:NamedThing	positive regulation of nucleotide metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.	got7fsn_ti	upregulation of nucleotide metabolic process|up regulation of nucleotide metabolic process|activation of nucleotide metabolic process|stimulation of nucleotide metabolic process|positive regulation of nucleotide metabolism|up-regulation of nucleotide metabolic process													biological_process											owl:Class	
GO:1904924	biolink:NamedThing	negative regulation of mitophagy in response to mitochondrial depolarization	Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.	got7fsn_ti	downregulation of mitophagy in response to mitochondrial depolarization|inhibition of mitophagy in response to mitochondrial depolarization|down-regulation of mitophagy in response to mitochondrial depolarization|down regulation of mitophagy in response to mitochondrial depolarization						pad	2016-01-26T11:23:58Z						biological_process											owl:Class	
GO:0032371	biolink:NamedThing	regulation of sterol transport	Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0062027	biolink:NamedThing	positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process	Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.	got7fsn_ti							dph	2018-04-16T14:05:19Z						biological_process											owl:Class	
GO:1990105	biolink:NamedThing	obsolete regulation of voltage-gated potassium channel activity	OBSOLETE. Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity.	got7fsn_ti	regulation of voltage-gated potassium channel activity				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2013-05-21T15:12:06Z		True				biological_process											owl:Class	
GO:0032876	biolink:NamedThing	negative regulation of DNA endoreduplication	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.	got7fsn_ti	downregulation of DNA endoreduplication|negative regulation of DNA re-duplication|down regulation of DNA endoreduplication|negative regulation of DNA endoreplication|inhibition of DNA endoreduplication|down-regulation of DNA endoreduplication													biological_process											owl:Class	
GO:0062236	biolink:NamedThing	ionocyte differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.	got7fsn_ti							dph	2020-04-20T12:30:35Z						biological_process											owl:Class	
GO:1903361	biolink:NamedThing	protein localization to basolateral plasma membrane	Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane.	got7fsn_ti	protein localisation in basolateral plasma membrane|protein localization in basolateral plasma membrane|protein localisation to basolateral plasma membrane|basolateral protein localization						dph	2012-10-19T13:58:04Z			GO:0061467			biological_process											owl:Class	
GO:1905404	biolink:NamedThing	positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process	Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.	got7fsn_ti	up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|upregulation of activated CD8-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T-cell apoptosis|activation of activated CD8-positive, alpha-beta T-cell apoptosis|up regulation of activated CD8-positive, alpha-beta T cell apoptosis|up-regulation of activated CD8-positive, alpha-beta T cell apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|positive regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|upregulation of activated CD8-positive, alpha-beta T cell apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T cell apoptosis|up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T-cell apoptosis|activation of activated CD8-positive, alpha-beta T cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|activation of activated CD8-positive, alpha-beta T-cell apoptotic process|activation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T cell apoptosis|upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T cell apoptosis|activation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T-cell apoptosis|up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-cell apoptosis|up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T cell apoptosis|up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process						pga	2016-08-25T09:14:10Z						biological_process											owl:Class	
GO:0075159	biolink:NamedThing	obsolete regulation of G-protein alpha subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1900629	biolink:NamedThing	methanophenazine metabolic process	The chemical reactions and pathways involving methanophenazine.	got7fsn_ti	methanophenazine metabolism						tt	2012-05-21T06:12:07Z						biological_process											owl:Class	
GO:0048301	biolink:NamedThing	positive regulation of isotype switching to IgD isotypes	Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes.	got7fsn_ti	positive regulation of class switch recombination to IgD isotypes|positive regulation of class switching to IgD isotypes|positive regulation of isotype switch recombination to IgD isotypes|upregulation of isotype switching to IgD isotypes|up-regulation of isotype switching to IgD isotypes|up regulation of isotype switching to IgD isotypes|activation of isotype switching to IgD isotypes|stimulation of isotype switching to IgD isotypes													biological_process											owl:Class	
GO:0006175	biolink:NamedThing	dATP biosynthetic process	The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).	got7fsn_ti	dATP synthesis|dATP anabolism|dATP biosynthesis|dATP formation													biological_process											owl:Class	
GO:0010596	biolink:NamedThing	negative regulation of endothelial cell migration	Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.	got7fsn_ti														biological_process											owl:Class	
GO:0015600	biolink:NamedThing	obsolete glutamate/aspartate porter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).	got7fsn_ti	glutamate/aspartate porter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015426|GO:0005313|GO:0015183				True				molecular_function											owl:Class	
GO:0046183	biolink:NamedThing	L-idonate catabolic process	The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	got7fsn_ti	L-idonate degradation|L-idonate breakdown|L-idonate catabolism													biological_process											owl:Class	
GO:1905321	biolink:NamedThing	negative regulation of mesenchymal stem cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration.	got7fsn_ti	down regulation of mesenchymal stem cell migration|inhibition of mesenchymal stem cell migration|downregulation of mesenchymal stem cell migration|down-regulation of mesenchymal stem cell migration						sl	2016-07-15T22:19:22Z						biological_process											owl:Class	
GO:1904081	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation	Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation.	got7fsn_ti	positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of transcription from RNA polymerase II promoter, global involved in neuron differentiation|up regulation of transcription from RNA polymerase II promoter involved in neuron differentiation|upregulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of global transcription from Pol II promoter involved in neuron differentiation|up regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|up-regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|stimulation of transcription from RNA polymerase II promoter involved in neuron differentiation|activation of transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of transcription from Pol II promoter involved in neuron differentiation|activation of global transcription from RNA polymerase II promoter involved in neuron differentiation|stimulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|up-regulation of transcription from RNA polymerase II promoter involved in neuron differentiation|upregulation of transcription from RNA polymerase II promoter involved in neuron differentiation						kmv	2015-03-24T20:15:59Z						biological_process											owl:Class	
GO:0035625	biolink:NamedThing	obsolete epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	OBSOLETE. The process in which an epidermal growth factor-activated receptor is activated via signaling events from a consequence of a G protein-coupled . This is an example of cross-talk between the EGF and GPCR signaling pathways.	got7fsn_ti	EGFR transactivation by GPCR|epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway|EGFR transactivation upon GPCR stimulation|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signalling pathway	https://github.com/geneontology/go-ontology/issues/15823			This term was obsoleted because it should be captured as a GO-CAM model.		bf	2010-12-08T04:19:12Z		True				biological_process											owl:Class	
GO:0003902	biolink:NamedThing	obsolete DNA-directed RNA polymerase III activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).	got7fsn_ti	DNA-directed RNA polymerase III activity			GO:0003899	This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase III complex ; GO:0005666'.					True				molecular_function											owl:Class	
GO:1905725	biolink:NamedThing	protein localization to microtubule end	A process in which a protein is transported to, or maintained in, a location at a microtubule end.	got7fsn_ti	protein localisation to microtubule end						mah	2016-11-28T15:01:43Z						biological_process											owl:Class	
GO:0072433	biolink:NamedThing	obsolete detection of DNA damage stimulus involved in mitotic G2 DNA damage checkpoint	OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic G2/M transition DNA damage checkpoint.	got7fsn_ti	sensing involved in mitotic G2/M transition DNA damage checkpoint|mitotic G2/M transition DNA damage checkpoint sensor process|detection of DNA damage stimulus involved in G2/M transition DNA damage checkpoint|G2/M transition DNA damage checkpoint sensor mechanism|detection of DNA damage stimulus involved in G2 DNA damage checkpoint|detection of DNA damage stimulus involved in mitotic G2/M transition DNA damage checkpoint|mitotic G2/M transition DNA damage checkpoint sensor mechanism|sensing involved in G2/M transition DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:43:14Z		True	GO:0072424			biological_process											owl:Class	
GO:0046497	biolink:NamedThing	nicotinate nucleotide metabolic process	The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin).	got7fsn_ti	nicotinate nucleotide metabolism													biological_process											owl:Class	
GO:0046045	biolink:NamedThing	TMP catabolic process	The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate.	got7fsn_ti	TMP degradation|TMP breakdown|TMP catabolism													biological_process											owl:Class	
GO:0042821	biolink:NamedThing	pyridoxal biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds.	got7fsn_ti	pyridoxal synthesis|pyridoxal formation|pyridoxal biosynthesis|pyridoxal anabolism													biological_process											owl:Class	
GO:1902155	biolink:NamedThing	regulation of response to G1 DNA damage checkpoint signaling	Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.	got7fsn_ti	regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling						jl	2013-05-21T15:44:53Z						biological_process											owl:Class	
GO:0001690	biolink:NamedThing	obsolete cytoplasmic dynein light chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytoplasmic dynein light chain			GO:0005868	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:1903788	biolink:NamedThing	positive regulation of glutathione biosynthetic process	Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process.	got7fsn_ti	up regulation of glutathione anabolism|activation of glutathione biosynthesis|up regulation of glutathione biosynthesis|upregulation of glutathione synthesis|up-regulation of glutathione synthesis|activation of glutathione anabolism|up-regulation of glutathione biosynthetic process|up-regulation of glutathione biosynthesis|positive regulation of glutathione anabolism|up-regulation of glutathione formation|activation of glutathione synthesis|upregulation of glutathione biosynthetic process|up-regulation of glutathione anabolism|positive regulation of glutathione biosynthesis|activation of glutathione biosynthetic process|positive regulation of glutathione formation|upregulation of glutathione anabolism|activation of glutathione formation|upregulation of glutathione formation|up regulation of glutathione synthesis|up regulation of glutathione formation|positive regulation of glutathione synthesis|upregulation of glutathione biosynthesis|up regulation of glutathione biosynthetic process						bf	2015-01-08T17:15:07Z						biological_process											owl:Class	
GO:0004192	biolink:NamedThing	obsolete cathepsin D activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His5 bond in the B chain of insulin.	got7fsn_ti	cathepsin D activity			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905518	biolink:NamedThing	regulation of presynaptic active zone assembly	Any process that modulates the frequency, rate or extent of presynaptic active zone assembly.	got7fsn_ti	regulation of pre-synaptic active zone assembly|regulation of pre-synaptic active zone component assembly|regulation of presynaptic active zone formation|regulation of pre-synaptic active zone formation|regulation of pre-synaptic active zone component formation						rl	2016-10-01T09:37:51Z						biological_process											owl:Class	
GO:1900249	biolink:NamedThing	positive regulation of cytoplasmic translational elongation	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.	got7fsn_ti	up-regulation of cytoplasmic translational elongation|activation of cytoplasmic translational elongation|up regulation of cytoplasmic translational elongation|upregulation of cytoplasmic translational elongation						vw	2012-04-03T05:07:24Z						biological_process											owl:Class	
CHEBI:58115	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000010	biolink:NamedThing	positive regulation of protein localization to cell surface	Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface.	got7fsn_ti	positive regulation of protein localization at cell surface|positive regulation of protein localisation at cell surface						jl	2010-08-04T01:43:56Z						biological_process											owl:Class	
GO:0050685	biolink:NamedThing	positive regulation of mRNA processing	Any process that activates or increases the frequency, rate or extent of mRNA processing.	got7fsn_ti	activation of mRNA processing|stimulation of mRNA processing|up-regulation of mRNA processing|up regulation of mRNA processing|upregulation of mRNA processing													biological_process											owl:Class	
GO:0045487	biolink:NamedThing	gibberellin catabolic process	The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.	got7fsn_ti	gibberellic acid breakdown|gibberellic acid degradation|gibberellic acid catabolism|gibberellic acid catabolic process|gibberellin catabolism													biological_process											owl:Class	
GO:1900730	biolink:NamedThing	negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.	got7fsn_ti	downregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|down regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|inhibition of adenylate cyclase-inhibiting opioid receptor signaling pathway|negative regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway|inhibition of opioid receptor-mediated adenylate cyclase inhibition|down-regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|negative regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway						bf	2012-05-25T03:21:12Z						biological_process											owl:Class	
GO:0071812	biolink:NamedThing	positive regulation of fever generation by positive regulation of prostaglandin secretion	Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	got7fsn_ti							mah	2010-09-03T05:10:36Z						biological_process											owl:Class	
GO:2000591	biolink:NamedThing	positive regulation of metanephric mesenchymal cell migration	Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.	got7fsn_ti	positive regulation of metanephric mesenchyme chemotaxis						bf	2011-04-07T03:29:53Z						biological_process											owl:Class	
GO:0071537	biolink:NamedThing	obsolete C3HC4-type RING finger domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a C3HC4-type RING finger domain interaction.	got7fsn_ti	zinc finger C3HC4 type domain-mediated complex assembly				This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T03:42:46Z		True				biological_process											owl:Class	
GO:0140123	biolink:NamedThing	negative regulation of Lewy body formation	Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14160					pg	2017-10-25T07:08:56Z						biological_process											owl:Class	
GO:0006549	biolink:NamedThing	isoleucine metabolic process	The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.	got7fsn_ti	isoleucine metabolism													biological_process											owl:Class	
GO:0043516	biolink:NamedThing	regulation of DNA damage response, signal transduction by p53 class mediator	Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.	got7fsn_ti	regulation of p53 induced by DNA damage response													biological_process											owl:Class	
GO:1901070	biolink:NamedThing	guanosine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines).	got7fsn_ti	guanosines synthesis|guanosines anabolism|guanosine-containing compound synthesis|guanosine-containing compound anabolism|guanosines biosynthetic process|guanosines formation|guanosine-containing compound formation|guanosine-containing compound biosynthesis|guanosines biosynthesis						bf	2012-07-02T01:52:09Z						biological_process											owl:Class	
GO:0009632	biolink:NamedThing	obsolete freezing tolerance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	freezing tolerance				This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process.	GO:0009409				True				biological_process											owl:Class	
GO:1902116	biolink:NamedThing	negative regulation of organelle assembly	Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.	got7fsn_ti	downregulation of organelle assembly|inhibition of organelle assembly|down-regulation of organelle assembly|down regulation of organelle assembly						pr	2013-05-14T09:43:31Z						biological_process											owl:Class	
GO:0046830	biolink:NamedThing	positive regulation of RNA import into nucleus	Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus.	got7fsn_ti	positive regulation of RNA-nucleus import|upregulation of RNA import into nucleus|up regulation of RNA import into nucleus|positive regulation of RNA transport from cytoplasm to nucleus|stimulation of RNA import into nucleus|positive regulation of RNA import into cell nucleus|up-regulation of RNA import into nucleus|activation of RNA import into nucleus													biological_process											owl:Class	
GO:0018179	biolink:NamedThing	obsolete peptidyl-cysteine desulfurization	OBSOLETE. The desulfurization of peptidyl-L-cysteine to yield L-alanine and elemental sulfur; peptidyl-L-cysteine persulfide is an intermediate.	got7fsn_ti	peptidyl-cysteine desulphurization|peptidyl-cysteine desulfurization				This term was made obsolete because to does not correspond to a real process.					True		RESID:AA0269		biological_process											owl:Class	
GO:2000773	biolink:NamedThing	negative regulation of cellular senescence	Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.	got7fsn_ti							bf	2011-06-22T01:57:08Z						biological_process											owl:Class	
GO:1903195	biolink:NamedThing	regulation of L-dopa biosynthetic process	Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process.	got7fsn_ti	regulation of L-dopa anabolism|regulation of L-dopa synthesis|regulation of L-dopa formation|regulation of L-dopa biosynthesis						bf	2014-07-21T09:12:37Z						biological_process											owl:Class	
GO:0071868	biolink:NamedThing	cellular response to monoamine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.	got7fsn_ti							mah	2010-09-13T02:38:52Z						biological_process											owl:Class	
GO:1903313	biolink:NamedThing	positive regulation of mRNA metabolic process	Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.	got7fsn_ti	up-regulation of mRNA metabolism|up regulation of mRNA metabolism|upregulation of mRNA metabolic process|up-regulation of mRNA metabolic process|positive regulation of mRNA metabolism|activation of mRNA metabolism|up regulation of mRNA metabolic process|upregulation of mRNA metabolism|activation of mRNA metabolic process						vw	2014-08-18T11:52:42Z						biological_process											owl:Class	
GO:0050675	biolink:NamedThing	regulation of urothelial cell proliferation	Any process that modulates the frequency, rate or extent of urothelial cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:1902112	biolink:NamedThing	cellular response to diethyl maleate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.	got7fsn_ti							mah	2013-05-08T16:00:40Z						biological_process											owl:Class	
GO:0048694	biolink:NamedThing	positive regulation of collateral sprouting of injured axon	Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon.	got7fsn_ti	stimulation of collateral sprouting of injured axon|up regulation of collateral sprouting of injured axon|up-regulation of collateral sprouting of injured axon|upregulation of collateral sprouting of injured axon|activation of collateral sprouting of injured axon													biological_process											owl:Class	
GO:0015534	biolink:NamedThing	obsolete proline/glycine/betaine:hydrogen/sodium symporter activity	OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in).	got7fsn_ti	proline/glycine/betaine:hydrogen/sodium symporter activity|proline/glycine/betaine:proton/sodium symporter				This term was made obsolete because it represents a multifunctional gene product.	GO:0015295|GO:0015370|GO:0015187|GO:0015294|GO:0015199|GO:0015193				True				molecular_function											owl:Class	
GO:1903459	biolink:NamedThing	mitotic DNA replication lagging strand elongation	Any lagging strand elongation that is involved in mitotic cell cycle DNA replication.	got7fsn_ti	lagging strand elongation involved in mitotic nuclear cell cycle DNA replication|lagging strand elongation involved in mitotic DNA replication|lagging strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle|lagging strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|lagging strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle|lagging strand elongation involved in DNA replication during S phase involved in mitotic cell cycle						vw	2014-09-23T13:32:54Z						biological_process											owl:Class	
GO:0045676	biolink:NamedThing	regulation of R7 cell differentiation	Any process that modulates the frequency, rate or extent of R7 differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0044328	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of endothelial cell migration.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in positive regulation of endothelial cell migration|canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration						jl	2010-08-18T04:01:05Z						biological_process											owl:Class	
GO:1905649	biolink:NamedThing	negative regulation of shell calcification	Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification.	got7fsn_ti	inhibition of shell calcification|down regulation of shell calcification|down-regulation of shell calcification|downregulation of shell calcification						pga	2016-11-08T16:24:43Z						biological_process											owl:Class	
GO:0075156	biolink:NamedThing	obsolete regulation of G protein-coupled receptor signaling pathway in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of G-protein coupled receptor protein signaling pathway in response to host|regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|regulation of G-protein coupled receptor protein signalling pathway in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:2001008	biolink:NamedThing	positive regulation of cellulose biosynthetic process	Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process.	got7fsn_ti	positive regulation of cellulose biosynthesis|positive regulation of cellulose synthesis|positive regulation of cellulose anabolism|positive regulation of cellulose formation						tt	2011-08-08T08:42:29Z						biological_process											owl:Class	
GO:2000030	biolink:NamedThing	regulation of response to red or far red light	Any process that modulates the frequency, rate or extent of response to red or far red light.	got7fsn_ti							tb	2010-08-05T11:30:10Z						biological_process											owl:Class	
GO:0060368	biolink:NamedThing	regulation of Fc receptor mediated stimulatory signaling pathway	Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.	got7fsn_ti	regulation of Fc receptor mediated stimulatory signalling pathway													biological_process											owl:Class	
GO:0035377	biolink:NamedThing	transepithelial water transport	The directed movement of water (H2O) from one side of an epithelium to the other.	got7fsn_ti							bf	2010-03-18T10:55:38Z						biological_process											owl:Class	
GO:2000911	biolink:NamedThing	positive regulation of sterol import	Any process that activates or increases the frequency, rate or extent of sterol import.	got7fsn_ti	positive regulation of sterol uptake|positive regulation of sterol influx						bf	2011-07-29T01:25:17Z						biological_process											owl:Class	
GO:1900956	biolink:NamedThing	regulation of 17-methylnonadec-1-ene biosynthetic process	Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.	got7fsn_ti	regulation of 17-methylnonadec-1-ene biosynthesis|regulation of 17-methylnonadec-1-ene anabolism|regulation of 17-methylnonadec-1-ene synthesis|regulation of 17-methylnonadec-1-ene formation						tt	2012-06-14T03:27:18Z						biological_process											owl:Class	
GO:1900534	biolink:NamedThing	palmitic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of palmitic acid.	got7fsn_ti							tb	2012-05-09T07:04:56Z						biological_process											owl:Class	
GO:0042847	biolink:NamedThing	sorbose biosynthetic process	The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.	got7fsn_ti	sorbose anabolism|sorbose biosynthesis|sorbose synthesis|sorbose formation													biological_process											owl:Class	
GO:0061846	biolink:NamedThing	dendritic spine cytoplasm	The region of the neuronal cytoplasm located in dendritic spines.	got7fsn_ti														cellular_component											owl:Class	
GO:0005809	biolink:NamedThing	obsolete Golgi-vacuole transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Golgi-vacuole transport vesicle				This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.	GO:0030133				True				cellular_component											owl:Class	
GO:0100053	biolink:NamedThing	obsolete positive regulation of sulfate assimilation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfate assimilation.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0034141	biolink:NamedThing	positive regulation of toll-like receptor 3 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.	got7fsn_ti	positive regulation of toll-like receptor 3 signalling pathway|positive regulation of TLR3 signaling pathway													biological_process											owl:Class	
GO:0052149	biolink:NamedThing	obsolete modulation by symbiont of host peptidase activity	OBSOLETE. The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host protease activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0060254	biolink:NamedThing	regulation of N-terminal protein palmitoylation	Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.	got7fsn_ti														biological_process											owl:Class	
GO:0019946	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090418	biolink:NamedThing	obsolete positive regulation of transcription involved in S-phase of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the S phase of the mitotic cell cycle.	got7fsn_ti	up-regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|positive regulation of transcription involved in S-phase of mitotic cell cycle|positive regulation of S phase specific transcription in the mitotic cell cycle|up-regulation of S phase specific transcription in the mitotic cell cycle|activation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|up-regulation of transcription involved in S phase of mitotic cell cycle|activation of S phase specific transcription in the mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|activation of transcription involved in S phase of mitotic cell cycle				This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0045944|GO:0000083	tb	2011-10-26T03:54:00Z		True				biological_process											owl:Class	
GO:0061093	biolink:NamedThing	negative regulation of phospholipid translocation	Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	got7fsn_ti							dph	2010-04-26T01:54:22Z						biological_process											owl:Class	
GO:0100007	biolink:NamedThing	obsolete negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates ceramide biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0033004	biolink:NamedThing	negative regulation of mast cell activation	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.	got7fsn_ti														biological_process											owl:Class	
GO:0010321	biolink:NamedThing	regulation of vegetative phase change	Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.	got7fsn_ti														biological_process											owl:Class	
GO:0034145	biolink:NamedThing	positive regulation of toll-like receptor 4 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.	got7fsn_ti	positive regulation of TLR4 signaling pathway|positive regulation of toll-like receptor 4 signalling pathway													biological_process											owl:Class	
GO:2000850	biolink:NamedThing	negative regulation of glucocorticoid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.	got7fsn_ti							bf	2011-07-26T08:44:48Z						biological_process											owl:Class	
GO:0071636	biolink:NamedThing	positive regulation of transforming growth factor beta production	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.	got7fsn_ti	positive regulation of TGF-B production|positive regulation of transforming growth factor-beta secretion|positive regulation of TGFB production|positive regulation of TGFbeta production|positive regulation of transforming growth factor-beta production|positive regulation of TGF-beta production						mah	2010-02-12T10:39:51Z			GO:2001203			biological_process											owl:Class	
GO:0001524	biolink:NamedThing	obsolete globin	OBSOLETE. The colorless and basic protein moiety of hemoglobin and myoglobins.	got7fsn_ti	globin			GO:0005344	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0051248	biolink:NamedThing	negative regulation of protein metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.	got7fsn_ti	down-regulation of protein metabolic process|negative regulation of protein metabolism|downregulation of protein metabolic process|inhibition of protein metabolic process|down regulation of protein metabolic process													biological_process											owl:Class	
GO:0045561	biolink:NamedThing	obsolete regulation of TRAIL receptor 1 biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.	got7fsn_ti	regulation of TRAIL receptor 1 biosynthesis|regulation of TRAIL receptor 1 synthesis|regulation of TRAIL receptor 1 anabolism|regulation of TRAIL receptor 1 formation	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:2000769	biolink:NamedThing	regulation of establishment or maintenance of cell polarity regulating cell shape	Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.	got7fsn_ti							mah	2011-06-22T01:56:49Z						biological_process											owl:Class	
GO:1902874	biolink:NamedThing	positive regulation of horizontal cell localization	Any process that activates or increases the frequency, rate or extent of horizontal cell localization.	got7fsn_ti	up regulation of horizontal cell localization|up regulation of horizontal cell localisation|positive regulation of laminar positioning of retinal horizontal cell|up-regulation of horizontal cell positioning|up-regulation of horizontal cell localization|activation of horizontal cell localization|positive regulation of retinal horizontal cell positioning|upregulation of retinal horizontal cell positioning|activation of retinal horizontal cell positioning|positive regulation of horizontal cell positioning|up-regulation of horizontal cell localisation|up regulation of horizontal cell positioning|positive regulation of horizontal cell localisation|activation of horizontal cell positioning|upregulation of horizontal cell localization|up regulation of laminar positioning of retinal horizontal cell|up regulation of retinal horizontal cell positioning|upregulation of laminar positioning of retinal horizontal cell|up-regulation of retinal horizontal cell positioning|activation of horizontal cell localisation|up-regulation of laminar positioning of retinal horizontal cell|upregulation of horizontal cell positioning|upregulation of horizontal cell localisation|activation of laminar positioning of retinal horizontal cell						mr	2014-04-03T15:25:09Z						biological_process											owl:Class	
GO:0051151	biolink:NamedThing	negative regulation of smooth muscle cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.	got7fsn_ti	down regulation of smooth muscle cell differentiation|down-regulation of smooth muscle cell differentiation|inhibition of smooth muscle cell differentiation|downregulation of smooth muscle cell differentiation													biological_process											owl:Class	
GO:0006040	biolink:NamedThing	amino sugar metabolic process	The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group.	got7fsn_ti	aminosaccharide metabolic process|amino sugar metabolism|aminosaccharide metabolism													biological_process											owl:Class	
GO:0001630	biolink:NamedThing	obsolete GP40-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	GP40-like receptor activity				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True				molecular_function											owl:Class	
GO:0009174	biolink:NamedThing	pyrimidine ribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside monophosphate biosynthesis|pyrimidine ribonucleoside monophosphate synthesis|pyrimidine ribonucleoside monophosphate anabolism|pyrimidine ribonucleoside monophosphate formation													biological_process											owl:Class	
GO:0002588	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.	got7fsn_ti	positive regulation of peptide antigen processing and presentation via MHC class II|up-regulation of antigen processing and presentation of peptide antigen via MHC class II|stimulation of antigen processing and presentation of peptide antigen via MHC class II|activation of antigen processing and presentation of peptide antigen via MHC class II|up regulation of antigen processing and presentation of peptide antigen via MHC class II|upregulation of antigen processing and presentation of peptide antigen via MHC class II													biological_process											owl:Class	
GO:0140116	biolink:NamedThing	fluoride export across plasma membrane	The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti							pg	2017-10-24T14:51:01Z						biological_process											owl:Class	
GO:1902692	biolink:NamedThing	regulation of neuroblast proliferation	Any process that modulates the frequency, rate or extent of neuroblast proliferation.	got7fsn_ti							rl	2014-02-18T10:03:31Z						biological_process											owl:Class	
GO:0005806	biolink:NamedThing	obsolete Golgi-ER transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Golgi-ER transport vesicle				This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.	GO:0030142				True				cellular_component											owl:Class	
GO:0017029	biolink:NamedThing	obsolete lysosomal protein stabilization	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lysosomal protein stabilization				This term was made obsolete because it contains both component and function information.	GO:0005764|GO:0050821				True				molecular_function											owl:Class	
GO:1900375	biolink:NamedThing	obsolete positive regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of inositol biosynthetic process.	got7fsn_ti	up-regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|activation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-17T12:45:48Z		True				biological_process											owl:Class	
GO:0110021	biolink:NamedThing	cardiac muscle myoblast proliferation	The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population.  A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.	got7fsn_ti							kmv	2017-06-29T14:35:24Z						biological_process											owl:Class	
GO:1902214	biolink:NamedThing	regulation of interleukin-4-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway.	got7fsn_ti	regulation of interleukin-4-mediated signalling pathway|regulation of IL-4-mediated signaling pathway						lb	2013-06-12T12:53:09Z						biological_process											owl:Class	
UBERON:0004188	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905458	biolink:NamedThing	positive regulation of lymphoid progenitor cell differentiation	Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation.	got7fsn_ti	up-regulation of lymphoid progenitor cell differentiation|activation of lymphoid progenitor cell differentiation|up regulation of lymphoid progenitor cell differentiation|upregulation of lymphoid progenitor cell differentiation						rz	2016-09-16T12:32:55Z						biological_process											owl:Class	
GO:1900723	biolink:NamedThing	negative regulation of protein adenylylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation.	got7fsn_ti	down-regulation of protein AMPylation|negative regulation of protein adenylation|downregulation of protein AMPylation|inhibition of protein amino acid adenylylation|down regulation of protein adenylylation|inhibition of protein AMPylation|downregulation of protein adenylylation|down regulation of protein amino acid adenylylation|inhibition of protein adenylylation|negative regulation of protein amino acid adenylylation|down-regulation of protein adenylylation|downregulation of protein amino acid adenylylation|downregulation of protein adenylation|negative regulation of protein AMPylation|inhibition of protein adenylation|down-regulation of protein adenylation|down regulation of protein AMPylation|down-regulation of protein amino acid adenylylation|down regulation of protein adenylation						jl	2012-05-24T03:16:06Z						biological_process											owl:Class	
CHEBI:16988	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015041	biolink:NamedThing	obsolete electron transfer flavoprotein, group II	OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that is synthesized only under certain specific growth conditions and receives electrons from the oxidation of specific substrates, e.g. trimethylamine, carnitine and in nitrogen fixation.	got7fsn_ti	electron transfer flavoprotein, group II			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:0005202	biolink:NamedThing	obsolete collagen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	collagen				This term was made obsolete because it does not represent a molecular function.	GO:0005581				True				molecular_function											owl:Class	
GO:0009600	biolink:NamedThing	detection of nematode	The series of events in which a stimulus from a nematode is received and converted into a molecular signal.	got7fsn_ti	perception of nematode													biological_process											owl:Class	
GO:0009480	biolink:NamedThing	obsolete class IIb cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	class IIb cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0090047	biolink:NamedThing	obsolete positive regulation of transcription regulator activity	OBSOLETE. Any process that increases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.	got7fsn_ti	positive regulation of transcription regulator activity				At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term.		tb	2009-08-07T10:24:24Z		True				biological_process											owl:Class	
GO:2000479	biolink:NamedThing	regulation of cAMP-dependent protein kinase activity	Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity.	got7fsn_ti	regulation of PKA|regulation of STK22|regulation of PKA C|regulation of 3',5'-cAMP-dependent protein kinase activity|regulation of protein kinase A activity|regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|regulation of 3',5' cAMP-dependent protein kinase activity|regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|regulation of cyclic AMP-dependent protein kinase activity|regulation of AMPK						yaf	2011-03-10T11:13:01Z						biological_process											owl:Class	
GO:1905388	biolink:NamedThing	cellular response to beta-carotene	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.	got7fsn_ti	cellular response to beta,beta-carotene						sl	2016-08-18T16:18:31Z						biological_process											owl:Class	
GO:0032686	biolink:NamedThing	negative regulation of hepatocyte growth factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production.	got7fsn_ti	down-regulation of hepatocyte growth factor production|downregulation of hepatocyte growth factor production|down regulation of hepatocyte growth factor production|inhibition of hepatocyte growth factor production|negative regulation of HGF production|negative regulation of scatter factor production|negative regulation of hepatocyte growth factor biosynthetic process										GO:0048178			biological_process											owl:Class	
GO:0051212	biolink:NamedThing	vanadium ion binding	Binding to a vanadium ion (V).	got7fsn_ti	V ion binding													molecular_function											owl:Class	
GO:0052523	biolink:NamedThing	obsolete positive regulation by organism of symbiont programmed cell death	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	enhancement or induction of symbiont programmed cell death|positive regulation by organism of symbiont programmed cell death				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0002298	biolink:NamedThing	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.	got7fsn_ti	CD4-positive, CD25-positive, alpha-beta T cell development involved in immune response|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0045716	biolink:NamedThing	obsolete positive regulation of low-density lipoprotein particle receptor biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors.	got7fsn_ti	up regulation of low-density lipoprotein receptor biosynthetic process|activation of low-density lipoprotein receptor biosynthetic process|up-regulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor biosynthesis|upregulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor biosynthetic process|stimulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor synthesis|positive regulation of low-density lipoprotein receptor formation|positive regulation of low-density lipoprotein receptor anabolism	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0048152	biolink:NamedThing	obsolete S100 beta biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.	got7fsn_ti	S100 beta formation|S100 beta anabolism|S100 beta biosynthesis|S100 beta synthesis	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0090485	biolink:NamedThing	obsolete chromosome number maintenance	OBSOLETE. The maintenance of the standard number of chromosomes in a cell.	got7fsn_ti	diploidization|haploidization				The reason for obsoletion is that this term represents a phenotype, and could be captured by other terms such as GO:0007059 chromosome segregation or GO:1903467 negative regulation of mitotic DNA replication initiation.	GO:0007059|GO:1903467	tb	2012-10-05T11:21:45Z		True				biological_process											owl:Class	
GO:0019677	biolink:NamedThing	NAD catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH.	got7fsn_ti	oxidized nicotinamide adenine dinucleotide catabolism|NAD catabolism|NAD breakdown|NAD (oxidized) catabolism|oxidized NAD catabolic process|NAD (reduced) catabolic process|oxidized nicotinamide adenine dinucleotide catabolic process|nicotinamide adenine dinucleotide catabolic process|NADH catabolic process|NAD (reduced) catabolism|NAD degradation|oxidized NAD catabolism|nicotinamide adenine dinucleotide catabolism|reduced NAD catabolism|reduced nicotinamide adenine dinucleotide catabolism|NAD (oxidized) catabolic process|NADH catabolism|reduced nicotinamide adenine dinucleotide catabolic process|reduced NAD catabolic process										GO:0006737			biological_process											owl:Class	
GO:0100055	biolink:NamedThing	obsolete positive regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylserine biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1902038	biolink:NamedThing	positive regulation of hematopoietic stem cell differentiation	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.	got7fsn_ti	up regulation of hemopoietic stem cell differentiation|up regulation of haematopoietic stem cell differentiation|activation of hematopoietic stem cell differentiation|up-regulation of hemopoietic stem cell differentiation|up regulation of haemopoietic stem cell differentiation|activation of hemopoietic stem cell differentiation|positive regulation of haemopoietic stem cell differentiation|up-regulation of hematopoietic stem cell differentiation|up-regulation of haemopoietic stem cell differentiation|upregulation of haemopoietic stem cell differentiation|upregulation of hematopoietic stem cell differentiation|up regulation of hematopoietic stem cell differentiation|upregulation of haematopoietic stem cell differentiation|positive regulation of hemopoietic stem cell differentiation|positive regulation of haematopoietic stem cell differentiation|upregulation of hemopoietic stem cell differentiation|activation of haematopoietic stem cell differentiation|up-regulation of haematopoietic stem cell differentiation|activation of haemopoietic stem cell differentiation						ss	2013-04-02T05:19:19Z						biological_process											owl:Class	
GO:1904093	biolink:NamedThing	negative regulation of autophagic cell death	Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death.	got7fsn_ti	downregulation of programmed cell death by macroautophagy|inhibition of type II programmed cell death|down-regulation of type II programmed cell death|down regulation of autophagic cell death|inhibition of autophagic cell death|down regulation of programmed cell death by macroautophagy|downregulation of autophagic cell death|negative regulation of type II programmed cell death|negative regulation of programmed cell death by macroautophagy|down-regulation of programmed cell death by macroautophagy|downregulation of type II programmed cell death|down regulation of type II programmed cell death|inhibition of programmed cell death by macroautophagy|down-regulation of autophagic cell death						bhm	2015-03-26T16:41:39Z						biological_process											owl:Class	
GO:0004998	biolink:NamedThing	transferrin receptor activity	Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.	got7fsn_ti														molecular_function											owl:Class	
GO:2000969	biolink:NamedThing	positive regulation of AMPA receptor activity	Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity.	got7fsn_ti	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity						pr	2011-08-03T10:27:08Z						biological_process											owl:Class	
GO:0045189	biolink:NamedThing	obsolete connective tissue growth factor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of CTGF, produced by human umbilical vein endothelial cells and by skin fibroblasts after activation with TGF-beta.	got7fsn_ti	connective tissue growth factor anabolism|CTGF biosynthesis|connective tissue growth factor biosynthesis|connective tissue growth factor formation|connective tissue growth factor synthesis				This term was obsoleted because it represent translation of a gene product, not a specific process.					True				biological_process											owl:Class	
GO:1904232	biolink:NamedThing	regulation of aconitate hydratase activity	Any process that modulates the frequency, rate or extent of aconitate hydratase activity.	got7fsn_ti	regulation of cis-aconitase activity|regulation of aconitase activity|regulation of citrate hydro-lyase activity|regulation of citrate(isocitrate) hydro-lyase activity|regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)						rl	2015-05-15T09:55:17Z						biological_process											owl:Class	
GO:0052515	biolink:NamedThing	obsolete positive regulation by organism of symbiont innate immunity	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont innate immune response|positive regulation by organism of symbiont innate immunity				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0015947	biolink:NamedThing	methane metabolic process	The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.	got7fsn_ti	methane metabolism													biological_process											owl:Class	
GO:0044151	biolink:NamedThing	obsolete growth of host on or near symbiont surface	OBSOLETE. The increase in size or mass of an organism occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth of organism on or near symbiont surface	https://github.com/geneontology/go-ontology/issues/18786			This term was obsoleted because it represents both a process and a location.		jl	2009-08-06T03:16:19Z		True				biological_process											owl:Class	
GO:0042213	biolink:NamedThing	m-cresol catabolic process	The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol.	got7fsn_ti	m-cresol degradation|3-hydroxytoluene catabolic process|m-cresol breakdown|meta-cresol catabolic process|m-cresol catabolism|3-hydroxytoluene catabolism|meta-cresol catabolism											UM-BBD_pathwayID:mcr|MetaCyc:M-CRESOL-DEGRADATION-PWY		biological_process											owl:Class	
GO:0061637	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007402	biolink:NamedThing	ganglion mother cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed.	got7fsn_ti														biological_process											owl:Class	
GO:0042217	biolink:NamedThing	1-aminocyclopropane-1-carboxylate catabolic process	The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.	got7fsn_ti	1-aminocyclopropane-1-carboxylate breakdown|1-aminocyclopropane-1-carboxylate catabolism|1-aminocyclopropane-1-carboxylate degradation													biological_process											owl:Class	
GO:2000757	biolink:NamedThing	negative regulation of peptidyl-lysine acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation.	got7fsn_ti							yaf	2011-06-16T09:51:31Z						biological_process											owl:Class	
GO:0044748	biolink:NamedThing	3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.	got7fsn_ti	exonucleolytic trimming to generate 3' end of miRNA						jl	2012-11-20T13:48:29Z						molecular_function											owl:Class	
GO:1901148	biolink:NamedThing	gene expression involved in extracellular matrix organization	Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.	got7fsn_ti	extracellular matrix protein production|expression of extracellular matrix proteins						bf	2012-07-16T03:29:30Z						biological_process											owl:Class	
GO:0006070	biolink:NamedThing	octanol metabolic process	The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH.	got7fsn_ti	octanol metabolism													biological_process											owl:Class	
GO:0007203	biolink:NamedThing	obsolete phosphatidylinositol-4,5-bisphosphate hydrolysis	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	phosphatidylinositol-4,5-bisphosphate hydrolysis				This term was made obsolete because hydrolysis is a reaction, not a process.	GO:0004435				True				biological_process											owl:Class	
GO:1905613	biolink:NamedThing	regulation of developmental vegetative growth	Any process that modulates the frequency, rate or extent of developmental vegetative growth.	got7fsn_ti							pga	2016-10-28T11:45:13Z						biological_process											owl:Class	
GO:1900412	biolink:NamedThing	obsolete regulation of histone methylation by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone methylation.	got7fsn_ti					This term was obsoleted because it describes a process that does not exist.		mah	2012-04-20T03:35:36Z		True				biological_process											owl:Class	
GO:1902710	biolink:NamedThing	GABA receptor complex	A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor.	got7fsn_ti	gamma-aminobutyric acid receptor complex						bhm	2014-02-20T16:07:48Z						cellular_component											owl:Class	
GO:0003718	biolink:NamedThing	obsolete RNA polymerase III transcription termination factor activity	OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase III.	got7fsn_ti	Pol III transcription termination factor activity|RNA polymerase III transcription termination factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006386				True				molecular_function											owl:Class	
GO:0003804	biolink:NamedThing	obsolete coagulation factor Xa activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin, and on factor VII, which it converts to a two-chain form (factor VIIa).	got7fsn_ti	Stuart factor activity|thrombokinase activity|thromboplastin|activated factor X|activated blood-coagulation factor X|blood coagulation factor X activity|factor Xa|Stuart factor|plasma thromboplastin|prothrombase activity|autoprothrombin C|coagulation factor Xa activity|activated Stuart-Prower factor|prothrombinase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0072478	biolink:NamedThing	obsolete detection of stimulus involved in mitotic spindle assembly checkpoint	OBSOLETE. The series of events in which information about whether the spindle is correctly assembled, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle assembly checkpoint.	got7fsn_ti	stimulus sensing involved in SAC-independent checkpoint|stimulus detection involved in SAC-independent checkpoint|detection of stimulus involved in mitotic cell cycle spindle assembly checkpoint|detection of stimulus involved in SAC-independent checkpoint|mitotic cell cycle spindle assembly checkpoint sensor process|mitotic cell cycle spindle assembly checkpoint sensor mechanism|sensing involved in mitotic cell cycle spindle assembly checkpoint|stimulus detection involved in DMA1-dependent checkpoint|detection of stimulus involved in Dma1-dependent checkpoint|stimulus sensing involved in DMA1-dependent checkpoint|perception of stimulus involved in DMA1-dependent checkpoint|perception of stimulus involved in SAC-independent checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T12:11:18Z		True	GO:1902419			biological_process											owl:Class	
GO:1904194	biolink:NamedThing	positive regulation of cholangiocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process.	got7fsn_ti	up regulation of cholangiocyte apoptotic process|upregulation of epithelial cell of bile duct apoptotic process|up regulation of epithelial cell of bile duct apoptosis|positive regulation of epithelial cell of bile duct apoptotic process|activation of cholangiocyte apoptosis|up-regulation of epithelial cell of bile duct apoptotic process|up-regulation of cholangiocyte apoptosis|activation of epithelial cell of bile duct apoptotic process|upregulation of cholangiocyte apoptosis|up-regulation of cholangiocyte apoptotic process|up-regulation of epithelial cell of bile duct apoptosis|upregulation of epithelial cell of bile duct apoptosis|activation of epithelial cell of bile duct apoptosis|positive regulation of epithelial cell of bile duct apoptosis|positive regulation of cholangiocyte apoptosis|upregulation of cholangiocyte apoptotic process|activation of cholangiocyte apoptotic process|up regulation of epithelial cell of bile duct apoptotic process|up regulation of cholangiocyte apoptosis						sl	2015-05-06T15:26:00Z						biological_process											owl:Class	
GO:0046617	biolink:NamedThing	obsolete nucleolar size increase (sensu Saccharomyces)	OBSOLETE. The process of nucleolar expansion, as seen in Saccharomyces.	got7fsn_ti	nucleolar size increase (sensu Saccharomyces)				This term was made obsolete because it does not describe a biological process.	GO:0007576|GO:0007571				True				biological_process											owl:Class	
GO:0120276	biolink:NamedThing	regulation of cerebral blood circulation	Any process that modulates the frequency, rate or extent of cerebral blood circulation.	got7fsn_ti	regulation of telencephalon blood circulation|regulation of cerebrum blood circulation	https://github.com/geneontology/go-ontology/issues/20107					krc	2020-10-21T06:52:22Z						biological_process											owl:Class	
GO:0045220	biolink:NamedThing	positive regulation of FasL production	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.	got7fsn_ti	up regulation of FasL biosynthetic process|up-regulation of FasL biosynthetic process|positive regulation of FasL formation|upregulation of FasL biosynthetic process|positive regulation of FasL anabolism|positive regulation of FasL biosynthesis|positive regulation of FasL biosynthetic process|stimulation of FasL biosynthetic process|positive regulation of FasL synthesis|activation of FasL biosynthetic process													biological_process											owl:Class	
GO:1903888	biolink:NamedThing	regulation of plant epidermal cell differentiation	Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation.	got7fsn_ti							tb	2015-02-06T22:29:38Z						biological_process											owl:Class	
GO:0099066	biolink:NamedThing	integral component of neuronal dense core vesicle membrane	The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0015254	biolink:NamedThing	glycerol channel activity	Enables the facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti												Reactome:R-HSA-432049|Reactome:R-HSA-432074|RHEA:29675|Reactome:R-HSA-507869|Reactome:R-HSA-507871		molecular_function											owl:Class	
GO:0043104	biolink:NamedThing	positive regulation of GTP cyclohydrolase I activity	Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I.	got7fsn_ti	upregulation of GTP cyclohydrolase I activity|up regulation of GTP cyclohydrolase I activity|up-regulation of GTP cyclohydrolase I activity|activation of GTP cyclohydrolase I activity|stimulation of GTP cyclohydrolase I activity													biological_process											owl:Class	
GO:2000567	biolink:NamedThing	regulation of memory T cell activation	Any process that modulates the frequency, rate or extent of memory T cell activation.	got7fsn_ti							ebc	2011-04-03T09:10:06Z						biological_process											owl:Class	
GO:0031922	biolink:NamedThing	pyridoxamine transport	The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:1902122	biolink:NamedThing	chenodeoxycholic acid binding	Binding to chenodeoxycholic acid.	got7fsn_ti	CDCA binding						bf	2013-05-16T09:17:19Z						molecular_function											owl:Class	
GO:1902860	biolink:NamedThing	propionyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of propionyl-CoA.	got7fsn_ti	propionyl-CoA synthesis|propionyl-CoA anabolism|propionyl-CoA biosynthesis|propionyl-CoA formation						tt	2014-04-03T03:10:29Z						biological_process											owl:Class	
GO:0075281	biolink:NamedThing	positive regulation of uredinium development	Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.	got7fsn_ti														biological_process											owl:Class	
GO:1904931	biolink:NamedThing	MCM complex binding	Binding to an MCM complex.	got7fsn_ti	mini-chromosome maintenance complex binding						mah	2016-01-29T11:48:10Z						molecular_function											owl:Class	
GO:0033139	biolink:NamedThing	regulation of peptidyl-serine phosphorylation of STAT protein	Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	got7fsn_ti	regulation of serine phosphorylation of STAT3 protein						mr	2014-08-06T21:22:57Z			GO:1903261			biological_process											owl:Class	
GO:1901381	biolink:NamedThing	positive regulation of potassium ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.	got7fsn_ti	up regulation of potassium ion transmembrane transport|positive regulation of potassium ion membrane transport|up-regulation of potassium ion transmembrane transport|upregulation of potassium ion transmembrane transport|activation of potassium ion transmembrane transport						rl	2012-09-28T15:59:25Z						biological_process											owl:Class	
UBERON:0004127	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901412	biolink:NamedThing	positive regulation of tetrapyrrole biosynthetic process from glutamate	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.	got7fsn_ti	up-regulation of tetrapyrrole formation from glutamate|activation of tetrapyrrole synthesis from glutamate|positive regulation of tetrapyrrole formation from glutamate|up-regulation of tetrapyrrole anabolism from glutamate|upregulation of tetrapyrrole biosynthesis from glutamate|up-regulation of tetrapyrrole biosynthetic process from glutamate|up-regulation of tetrapyrrole synthesis from glutamate|upregulation of tetrapyrrole anabolism from glutamate|activation of tetrapyrrole biosynthetic process from glutamate|upregulation of tetrapyrrole biosynthetic process from glutamate|positive regulation of tetrapyrrole biosynthesis from glutamate|up regulation of tetrapyrrole biosynthesis from glutamate|positive regulation of tetrapyrrole synthesis from glutamate|activation of tetrapyrrole formation from glutamate|activation of tetrapyrrole anabolism from glutamate|activation of tetrapyrrole biosynthesis from glutamate|up-regulation of tetrapyrrole biosynthesis from glutamate|up regulation of tetrapyrrole synthesis from glutamate|up regulation of tetrapyrrole anabolism from glutamate|positive regulation of tetrapyrrole anabolism from glutamate|up regulation of tetrapyrrole formation from glutamate|upregulation of tetrapyrrole synthesis from glutamate|up regulation of tetrapyrrole biosynthetic process from glutamate|upregulation of tetrapyrrole formation from glutamate						tt	2012-10-01T16:22:21Z						biological_process											owl:Class	
GO:1901875	biolink:NamedThing	positive regulation of post-translational protein modification	Any process that activates or increases the frequency, rate or extent of post-translational protein modification.	got7fsn_ti	positive regulation of post-translational amino acid modification|upregulation of PTM|up regulation of post-translational amino acid modification|activation of post-translational amino acid modification|upregulation of post-translational protein modification|up-regulation of post-translational modification|up-regulation of post-translational amino acid modification|up regulation of posttranslational protein modification|activation of PTM|positive regulation of post-translational modification|positive regulation of posttranslational modification|up-regulation of post-translational protein modification|up regulation of post-translational protein modification|up regulation of posttranslational modification|positive regulation of posttranslational amino acid modification|positive regulation of PTM|up regulation of posttranslational amino acid modification|activation of posttranslational protein modification|up-regulation of posttranslational modification|upregulation of posttranslational protein modification|activation of post-translational modification|upregulation of post-translational modification|activation of post-translational protein modification|upregulation of posttranslational amino acid modification|upregulation of posttranslational modification|positive regulation of posttranslational protein modification|up-regulation of posttranslational amino acid modification|up-regulation of PTM|up regulation of PTM|up regulation of post-translational modification|activation of posttranslational modification|activation of posttranslational amino acid modification|up-regulation of posttranslational protein modification|upregulation of post-translational amino acid modification						yaf	2013-02-05T10:03:02Z						biological_process											owl:Class	
GO:1904879	biolink:NamedThing	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.	got7fsn_ti	upregulation of generation of L-type calcium current|positive regulation of generation of L-type calcium current|up regulation of generation of L-type calcium current|activation of generation of L-type calcium current|up-regulation of generation of L-type calcium current						sl	2015-12-18T22:30:44Z						biological_process											owl:Class	
GO:1904328	biolink:NamedThing	regulation of myofibroblast contraction	Any process that modulates the frequency, rate or extent of myofibroblast contraction.	got7fsn_ti	regulation of MF contraction|regulation of MFB contraction						sl	2015-06-11T15:30:29Z						biological_process											owl:Class	
GO:1902730	biolink:NamedThing	positive regulation of proteoglycan biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	got7fsn_ti	upregulation of proteoglycan biosynthetic process|up regulation of proteoglycan biosynthetic process|upregulation of proteoglycan biosynthesis|up-regulation of proteoglycan synthesis|up regulation of proteoglycan formation|up regulation of proteoglycan biosynthesis|positive regulation of proteoglycan anabolism|up regulation of proteoglycan synthesis|up-regulation of proteoglycan anabolism|activation of proteoglycan synthesis|up regulation of proteoglycan anabolism|positive regulation of proteoglycan formation|up-regulation of proteoglycan biosynthesis|upregulation of proteoglycan synthesis|positive regulation of proteoglycan biosynthesis|activation of proteoglycan biosynthetic process|up-regulation of proteoglycan biosynthetic process|upregulation of proteoglycan anabolism|activation of proteoglycan anabolism|activation of proteoglycan formation|positive regulation of proteoglycan synthesis|upregulation of proteoglycan formation|up-regulation of proteoglycan formation|activation of proteoglycan biosynthesis						mr	2014-02-24T16:10:52Z						biological_process											owl:Class	
GO:0030471	biolink:NamedThing	obsolete spindle pole body and microtubule cycle (sensu Fungi)	OBSOLETE. The dynamics of the spindle pole body and microtubule cytoskeleton during the cell cycle. Includes spindle pole body duplication and separation and formation and elongation of the mitotic spindle. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).	got7fsn_ti	spindle pole body and microtubule cycle (sensu Fungi)|spindle pole body and microtubule cycle (sensu Saccharomyces)				This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful entity.	GO:0051300|GO:0007051				True	GO:0007102			biological_process											owl:Class	
PR:000001374	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004717	biolink:NamedThing	obsolete focal adhesion kinase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	FAK|focal adhesion kinase activity			GO:0004713	This term was made obsolete because it represents a gene product, and because the gene was named after its location of action rather than after its molecular function.					True				molecular_function											owl:Class	
GO:0097308	biolink:NamedThing	cellular response to farnesol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.	got7fsn_ti							pr	2012-05-15T03:54:01Z						biological_process											owl:Class	
GO:0045627	biolink:NamedThing	positive regulation of T-helper 1 cell differentiation	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.	got7fsn_ti	up regulation of T-helper 1 cell differentiation|activation of T-helper 1 cell differentiation|upregulation of T-helper 1 cell differentiation|up-regulation of T-helper 1 cell differentiation|stimulation of T-helper 1 cell differentiation|positive regulation of T-helper 1 cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0010181	biolink:NamedThing	FMN binding	Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.	got7fsn_ti	flavin mononucleotide binding													molecular_function											owl:Class	
GO:1901115	biolink:NamedThing	erythromycin biosynthetic process	The chemical reactions and pathways resulting in the formation of erythromycin.	got7fsn_ti	erythromycin synthesis|erythromycin anabolism|erythromycin biosynthesis|erythromycin formation						yaf	2012-07-11T03:06:46Z						biological_process											owl:Class	
GO:1904828	biolink:NamedThing	positive regulation of hydrogen sulfide biosynthetic process	Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process.	got7fsn_ti	positive regulation of hydrogen sulfide synthesis|activation of hydrogen sulphide biosynthesis|up regulation of hydrogen sulfide biosynthetic process|positive regulation of hydrogen sulfide formation|up-regulation of hydrogen sulfide anabolism|positive regulation of hydrogen sulfide anabolism|positive regulation of hydrogen sulphide biosynthetic process|upregulation of hydrogen sulphide biosynthesis|up-regulation of hydrogen sulfide biosynthesis|up-regulation of hydrogen sulfide formation|up regulation of hydrogen sulphide biosynthesis|activation of hydrogen sulfide biosynthesis|up regulation of hydrogen sulfide synthesis|up regulation of hydrogen sulfide biosynthesis|activation of hydrogen sulfide anabolism|up-regulation of hydrogen sulphide biosynthesis|up-regulation of hydrogen sulphide biosynthetic process|up regulation of hydrogen sulfide anabolism|upregulation of hydrogen sulfide biosynthesis|upregulation of hydrogen sulfide synthesis|up regulation of hydrogen sulphide biosynthetic process|activation of hydrogen sulfide synthesis|up-regulation of hydrogen sulfide synthesis|positive regulation of hydrogen sulfide biosynthesis|up-regulation of hydrogen sulfide biosynthetic process|activation of hydrogen sulfide formation|upregulation of hydrogen sulfide biosynthetic process|up regulation of hydrogen sulfide formation|activation of hydrogen sulphide biosynthetic process|upregulation of hydrogen sulfide anabolism|activation of hydrogen sulfide biosynthetic process|upregulation of hydrogen sulfide formation|upregulation of hydrogen sulphide biosynthetic process|positive regulation of hydrogen sulphide biosynthesis						rph	2015-11-24T10:15:41Z						biological_process											owl:Class	
GO:0050478	biolink:NamedThing	obsolete anthranilate 3-monooxygenase activity	OBSOLETE. Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + anthranilate + O(2) = 3-hydroxyanthranilate + 7,8-dihydrobiopterin + H(2)O.	got7fsn_ti	anthranilate,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|anthranilic acid hydroxylase activity|anthranilate 3-hydroxylase activity				This term is slated for obsoletion;  According to RHEA the activity does not exist.					True				molecular_function											owl:Class	
GO:0030404	biolink:NamedThing	obsolete collagenase 3 activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	matrix metalloproteinase 13|MMP-13|collagenase 3 activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0043388	biolink:NamedThing	positive regulation of DNA binding	Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).	got7fsn_ti	upregulation of DNA binding|up regulation of DNA binding|up-regulation of DNA binding|activation of DNA binding|stimulation of DNA binding													biological_process											owl:Class	
GO:1904376	biolink:NamedThing	negative regulation of protein localization to cell periphery	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery.	got7fsn_ti	inhibition of protein localization to cell periphery|down regulation of protein localization to cell periphery|down-regulation of protein localization to cell periphery|downregulation of protein localization to cell periphery						sl	2015-06-22T22:09:32Z						biological_process											owl:Class	
GO:0090249	biolink:NamedThing	regulation of cell migration involved in somitogenic axis elongation	Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.	got7fsn_ti	regulation of cell motility involved in somitogenic axis elongation	https://github.com/geneontology/go-annotation/issues/2040					tb	2010-01-22T11:20:05Z						biological_process											owl:Class	
GO:0014067	biolink:NamedThing	negative regulation of phosphatidylinositol 3-kinase signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.	got7fsn_ti	negative regulation of phosphoinositide 3-kinase cascade|inhibition of phosphatidylinositol 3-kinase cascade|negative regulation of PI 3-kinase cascade|downregulation of phosphatidylinositol 3-kinase cascade|negative regulation of PI3K cascade|down-regulation of phosphatidylinositol 3-kinase cascade|down regulation of phosphatidylinositol 3-kinase cascade|negative regulation of phosphatidylinositol 3-kinase cascade													biological_process											owl:Class	
GO:0046823	biolink:NamedThing	negative regulation of nucleocytoplasmic transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.	got7fsn_ti	inhibition of nucleocytoplasmic transport|down-regulation of nucleocytoplasmic transport|downregulation of nucleocytoplasmic transport|down regulation of nucleocytoplasmic transport													biological_process											owl:Class	
GO:2000523	biolink:NamedThing	regulation of T cell costimulation	Any process that modulates the frequency, rate or extent of T cell costimulation.	got7fsn_ti	regulation of T cell co-stimulation|regulation of T-lymphocyte costimulation|regulation of T-cell costimulation|regulation of T-cell co-stimulation|regulation of T lymphocyte costimulation						ebc	2011-03-23T10:23:24Z						biological_process											owl:Class	
GO:1901278	biolink:NamedThing	D-ribose 5-phosphate metabolic process	The chemical reactions and pathways involving D-ribose 5-phosphate.	got7fsn_ti	D-ribose 5-phosphate metabolism						yaf	2012-08-17T14:59:58Z						biological_process											owl:Class	
GO:1902395	biolink:NamedThing	regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity	Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity.	got7fsn_ti	regulation of DXP-synthase activity|regulation of 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity|regulation of DOXP synthase activity|regulation of 1-deoxyxylulose-5-phosphate synthase activity|regulation of pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)						tb	2013-09-11T21:12:25Z						biological_process											owl:Class	
GO:1901470	biolink:NamedThing	negative regulation of syringal lignin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.	got7fsn_ti	down regulation of syringal lignin catabolic process|down regulation of syringal lignin degradation|negative regulation of syringal lignin breakdown|inhibition of syringal lignin breakdown|down regulation of syringal lignin catabolism|downregulation of syringal lignin catabolic process|negative regulation of syringal lignin degradation|down regulation of syringal lignin breakdown|down-regulation of syringal lignin catabolic process|inhibition of S-lignin catabolic process|downregulation of syringal lignin breakdown|downregulation of syringal lignin degradation|down-regulation of S-lignin catabolic process|negative regulation of S-lignin catabolic process|downregulation of S-lignin catabolic process|down-regulation of syringal lignin degradation|down-regulation of syringal lignin breakdown|down-regulation of syringal lignin catabolism|inhibition of syringal lignin degradation|inhibition of syringal lignin catabolic process|down regulation of S-lignin catabolic process|negative regulation of syringal lignin catabolism|downregulation of syringal lignin catabolism|inhibition of syringal lignin catabolism						tt	2012-10-02T14:42:21Z						biological_process											owl:Class	
GO:1905402	biolink:NamedThing	regulation of activated CD8-positive, alpha-beta T cell apoptotic process	Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.	got7fsn_ti	regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|regulation of activated CD8-positive, alpha-beta T cell apoptosis|regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|regulation of activated CD8-positive, alpha-beta T-cell apoptosis|regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process						pga	2016-08-25T09:13:56Z						biological_process											owl:Class	
GO:1901493	biolink:NamedThing	response to decalin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus.	got7fsn_ti							tt	2012-10-16T13:41:09Z						biological_process											owl:Class	
GO:0008500	biolink:NamedThing	obsolete glycine-, glutamate-, thienylcyclohexylpiperidine binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	glycine-, glutamate-, thienylcyclohexylpiperidine binding				This term was made obsolete because it is a conglomeration of three terms.	GO:0016594|GO:0016596|GO:0016595				True				molecular_function											owl:Class	
GO:0046604	biolink:NamedThing	positive regulation of mitotic centrosome separation	Any process that activates or increases the frequency, rate or extent of centrosome separation.	got7fsn_ti	up-regulation of mitotic centrosome separation|stimulation of mitotic centrosome separation|activation of mitotic centrosome separation|upregulation of mitotic centrosome separation|up regulation of mitotic centrosome separation													biological_process											owl:Class	
GO:0044539	biolink:NamedThing	long-chain fatty acid import into cell	The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain fatty acid uptake|long-chain fatty acid import						jl	2012-03-21T03:34:04Z						biological_process											owl:Class	
GO:1904030	biolink:NamedThing	negative regulation of cyclin-dependent protein kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity.	got7fsn_ti	downregulation of cyclin-dependent protein kinase activity|inhibition of cyclin-dependent protein kinase activity|down-regulation of cyclin-dependent protein kinase activity|down regulation of cyclin-dependent protein kinase activity						als	2015-03-13T15:43:44Z						biological_process											owl:Class	
GO:2000209	biolink:NamedThing	regulation of anoikis	Any process that modulates the frequency, rate or extent of anoikis.	got7fsn_ti	regulation of suspension induced apoptosis|regulation of detachment induced cell death						mah	2010-11-03T02:00:33Z						biological_process											owl:Class	
GO:0106201	biolink:NamedThing	obsolete translocase activity acting on amino acids and peptides linked to the hydrolysis of a diphosphate	OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a diphosphate.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:28:18Z		True		EC:7.4.3.-		molecular_function											owl:Class	
GO:0070428	biolink:NamedThing	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.	got7fsn_ti	regulation of NOD1 signaling pathway|regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway													biological_process											owl:Class	
GO:1905917	biolink:NamedThing	positive regulation of cell differentiation involved in phenotypic switching	Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching.	got7fsn_ti	upregulation of cell differentiation involved in phenotypic switching|up regulation of cell differentiation involved in phenotypic switching|activation of cell differentiation involved in phenotypic switching|up-regulation of cell differentiation involved in phenotypic switching						rph	2017-02-08T12:23:31Z						biological_process											owl:Class	
GO:0045706	biolink:NamedThing	positive regulation of salivary gland boundary specification	Any process that activates or increases the frequency, rate or extent of salivary gland determination.	got7fsn_ti	up-regulation of salivary gland determination|up regulation of salivary gland determination|stimulation of salivary gland determination|activation of salivary gland determination|upregulation of salivary gland determination|positive regulation of salivary gland determination													biological_process											owl:Class	
GO:1901940	biolink:NamedThing	(-)-exo-alpha-bergamotene biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene.	got7fsn_ti	(-)-exo-alpha-bergamotene anabolism|(-)-exo-alpha-bergamotene biosynthesis|(-)-exo-alpha-bergamotene formation|(-)-exo-alpha-bergamotene synthesis						ms	2013-02-18T14:55:32Z						biological_process											owl:Class	
UBERON:0004135	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001061	biolink:NamedThing	obsolete bacterial-type RNA polymerase activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a bacterial-type specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16738		GO:0003899	This term was obsoleted because the activity is the same as its parent.		krc	2010-10-19T03:36:01Z		True				molecular_function											owl:Class	
GO:0031496	biolink:NamedThing	positive regulation of mating type switching	Any process that activates or increases the frequency, rate or extent of mating type switching.	got7fsn_ti	upregulation of mating type switching|activation of mating type switching|stimulation of mating type switching|up regulation of mating type switching|up-regulation of mating type switching													biological_process											owl:Class	
GO:0010352	biolink:NamedThing	lithium ion export across the plasma membrane	The directed movement of lithium ion out of a cell or organelle.	got7fsn_ti	lithium ion export|lithium ion efflux|lithium export													biological_process											owl:Class	
GO:0090414	biolink:NamedThing	molybdate ion export from vacuole	The directed movement of molybdate ions out of the vacuole.	got7fsn_ti							tb	2011-09-15T02:08:43Z						biological_process											owl:Class	
CHEBI:28887	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045572	biolink:NamedThing	positive regulation of imaginal disc growth	Any process that activates or increases the frequency, rate or extent of imaginal disc growth.	got7fsn_ti	up-regulation of imaginal disc growth|up regulation of imaginal disc growth|upregulation of imaginal disc growth|activation of imaginal disc growth|stimulation of imaginal disc growth													biological_process											owl:Class	
GO:1901734	biolink:NamedThing	quercetin biosynthetic process	The chemical reactions and pathways resulting in the formation of quercetin.	got7fsn_ti	quercetin formation|quercetin biosynthesis|quercetin synthesis|quercetin anabolism						yaf	2013-01-11T10:25:20Z						biological_process											owl:Class	
GO:0001953	biolink:NamedThing	negative regulation of cell-matrix adhesion	Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.	got7fsn_ti	inhibition of cell-matrix adhesion|downregulation of cell-matrix adhesion|down regulation of cell-matrix adhesion|down-regulation of cell-matrix adhesion													biological_process											owl:Class	
GO:1903173	biolink:NamedThing	fatty alcohol metabolic process	The chemical reactions and pathways involving fatty alcohol.	got7fsn_ti	fatty alcohol metabolism						tt	2014-07-14T01:51:41Z						biological_process											owl:Class	
GO:1905229	biolink:NamedThing	cellular response to thyrotropin-releasing hormone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.	got7fsn_ti	cellular response to protirelin|cellular response to TRH						sl	2016-06-07T16:14:10Z						biological_process											owl:Class	
GO:1904165	biolink:NamedThing	obsolete positive regulation of triglyceride homeostasis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of triglyceride homeostasis.	got7fsn_ti	upregulation of triglyceride homeostasis|positive regulation of triacylglycerol homeostasis|up regulation of triglyceride homeostasis|activation of triacylglycerol homeostasis|up-regulation of triacylglycerol homeostasis|up regulation of triacylglycerol homeostasis|up-regulation of triglyceride homeostasis|upregulation of triacylglycerol homeostasis|activation of triglyceride homeostasis				This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2015-04-22T11:04:55Z		True				biological_process											owl:Class	
GO:1901543	biolink:NamedThing	negative regulation of ent-pimara-8(14),15-diene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.	got7fsn_ti	down regulation of ent-pimara-8(14),15-diene biosynthesis|negative regulation of ent-pimara-8(14),15-diene synthesis|down regulation of ent-pimara-8(14),15-diene biosynthetic process|negative regulation of ent-pimara-8(14),15-diene anabolism|inhibition of ent-pimara-8(14),15-diene biosynthesis|negative regulation of ent-pimara-8(14),15-diene formation|downregulation of ent-pimara-8(14),15-diene anabolism|downregulation of ent-pimara-8(14),15-diene synthesis|down regulation of ent-pimara-8(14),15-diene formation|downregulation of ent-pimara-8(14),15-diene biosynthesis|down-regulation of ent-pimara-8(14),15-diene biosynthetic process|inhibition of ent-pimara-8(14),15-diene synthesis|down regulation of ent-pimara-8(14),15-diene synthesis|inhibition of ent-pimara-8(14),15-diene anabolism|inhibition of ent-pimara-8(14),15-diene formation|down-regulation of ent-pimara-8(14),15-diene synthesis|inhibition of ent-pimara-8(14),15-diene biosynthetic process|down regulation of ent-pimara-8(14),15-diene anabolism|downregulation of ent-pimara-8(14),15-diene biosynthetic process|down-regulation of ent-pimara-8(14),15-diene formation|negative regulation of ent-pimara-8(14),15-diene biosynthesis|down-regulation of ent-pimara-8(14),15-diene anabolism|down-regulation of ent-pimara-8(14),15-diene biosynthesis|downregulation of ent-pimara-8(14),15-diene formation						di	2012-10-26T11:37:58Z						biological_process											owl:Class	
GO:1904824	biolink:NamedThing	anaphase-promoting complex assembly	The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex.	got7fsn_ti	anaphase promoting complex formation|APC assembly|cyclosome formation|anaphase promoting complex assembly|anaphase-promoting complex formation|cyclosome assembly						mah	2015-11-23T12:28:59Z						biological_process											owl:Class	
GO:0004219	biolink:NamedThing	obsolete pyroglutamyl-peptidase I activity	OBSOLETE. Catalysis of the reaction: pyroglutamyl-peptide + H2O = pyroglutamate + peptide.	got7fsn_ti	pyrrolidonyl peptidase activity|L-pyroglutamyl peptide hydrolase activity|L-pyrrolidonecarboxylate peptidase activity|pyrrolidone-carboxyl peptidase activity|5-oxoprolyl-peptidase activity|pyroglutamidase activity|pyroglutamate aminopeptidase activity|PYRase activity|pyrrolidone carboxyl peptidase activity|pyroglutamyl aminopeptidase activity|pyrrolidone-carboxylate peptidase activity|pyrrolidonecarboxylyl peptidase activity|pyroglutamyl-peptidase I activity				This term was made obsolete because it represents a gene product.	GO:0016920|GO:0008234				True		EC:3.4.19.3|MetaCyc:PYROGLUTAMYL-PEPTIDASE-I-RXN		molecular_function											owl:Class	
GO:1902305	biolink:NamedThing	regulation of sodium ion transmembrane transport	Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.	got7fsn_ti	regulation of sodium ion membrane transport						rl	2013-07-18T13:33:53Z						biological_process											owl:Class	
GO:0007180	biolink:NamedThing	obsolete transforming growth factor beta ligand binding to type II receptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	TGF-beta ligand binding to type II receptor|transforming growth factor beta ligand binding to type II receptor|TGFbeta ligand binding to type II receptor				This term was made obsolete because it represents a function.	GO:0005160|GO:0050431|GO:0005026				True				biological_process											owl:Class	
GO:0051538	biolink:NamedThing	3 iron, 4 sulfur cluster binding	Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.	got7fsn_ti	triiron tetrasulfide cluster binding|iron-sulphur cluster 3Fe-4S binding|triiron tetrasulphide cluster binding|3 Fe 4 S cluster binding|3Fe-4S cluster binding|iron-sulfur cluster 3Fe-4S binding|3 iron, 4 sulphur cluster binding													molecular_function											owl:Class	
GO:2001221	biolink:NamedThing	obsolete positive regulation of G2 phase of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of G2 phase of mitotic cell cycle.	got7fsn_ti	positive regulation of G2 phase of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.		yaf	2011-11-17T03:28:48Z		True				biological_process											owl:Class	
GO:1902989	biolink:NamedThing	meiotic telomere maintenance via semi-conservative replication	Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle.	got7fsn_ti	telomeric fork progression involved in meiotic cell cycle|equal telomere replication involved in meiotic cell cycle|telomeric replication fork progression involved in meiotic cell cycle						jl	2014-05-08T11:13:43Z						biological_process											owl:Class	
GO:1902057	biolink:NamedThing	(25S)-Delta(4)-dafachronate metabolic process	The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate.	got7fsn_ti	(25S)-Delta(4)-dafachronate metabolism						ab	2013-04-13T09:22:54Z						biological_process											owl:Class	
GO:2001303	biolink:NamedThing	lipoxin A4 biosynthetic process	The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.	got7fsn_ti	lipoxin A4 biosynthesis|LXA4 anabolism|LXA4 biosynthesis|LXA4 formation|lipoxin A4 formation|LXA4 biosynthetic process|lipoxin A4 synthesis|LXA4 synthesis|lipoxin A4 anabolism						bf	2012-03-07T11:13:18Z						biological_process											owl:Class	
GO:0050730	biolink:NamedThing	regulation of peptidyl-tyrosine phosphorylation	Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.	got7fsn_ti														biological_process											owl:Class	
GO:0010509	biolink:NamedThing	polyamine homeostasis	Any biological process involved in the maintenance of an internal steady state of a polyamine.	got7fsn_ti														biological_process											owl:Class	
GO:0045657	biolink:NamedThing	positive regulation of monocyte differentiation	Any process that activates or increases the frequency, rate or extent of monocyte differentiation.	got7fsn_ti	up-regulation of monocyte differentiation|up regulation of monocyte differentiation|activation of monocyte differentiation|stimulation of monocyte differentiation|upregulation of monocyte differentiation													biological_process											owl:Class	
GO:0046002	biolink:NamedThing	positive regulation of preblastoderm mitotic cell cycle	Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle.	got7fsn_ti	stimulation of progression through preblastoderm mitotic cell cycle|upregulation of progression through preblastoderm mitotic cell cycle|positive regulation of preblastoderm mitotic cell cycle progression|positive regulation of progression through preblastoderm mitotic cell cycle|activation of progression through preblastoderm mitotic cell cycle|up regulation of progression through preblastoderm mitotic cell cycle|up-regulation of progression through preblastoderm mitotic cell cycle													biological_process											owl:Class	
GO:0008159	biolink:NamedThing	obsolete positive transcription elongation factor activity	OBSOLETE. Any activity that increases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation.	got7fsn_ti	positive transcription elongation factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0032786				True				molecular_function											owl:Class	
GO:2000430	biolink:NamedThing	positive regulation of neutrophil aggregation	Any process that activates or increases the frequency, rate or extent of neutrophil aggregation.	got7fsn_ti	positive regulation of neutrophil leucocyte aggregation|positive regulation of neutrocyte aggregation|positive regulation of neutrophilic leukocyte aggregation						ebc	2011-02-28T05:19:51Z						biological_process											owl:Class	
GO:2000953	biolink:NamedThing	positive regulation of xyloglucan catabolic process	Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process.	got7fsn_ti	positive regulation of xyloglucan catabolism						tt	2011-08-01T02:20:26Z						biological_process											owl:Class	
PR:000001255	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901462	biolink:NamedThing	positive regulation of response to formic acid	Any process that activates or increases the frequency, rate or extent of response to formic acid.	got7fsn_ti	up regulation of response to formic acid|up-regulation of response to formic acid|activation of response to formic acid|upregulation of response to formic acid						tt	2012-10-02T14:29:20Z						biological_process											owl:Class	
GO:1900062	biolink:NamedThing	obsolete regulation of replicative cell aging	OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging.	got7fsn_ti	regulation of replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.		dph	2012-01-26T01:46:47Z		True				biological_process											owl:Class	
GO:0019307	biolink:NamedThing	mannose biosynthetic process	The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.	got7fsn_ti	mannose synthesis|mannose formation|mannose anabolism|mannose biosynthesis													biological_process											owl:Class	
GO:0043536	biolink:NamedThing	positive regulation of blood vessel endothelial cell migration	Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.	got7fsn_ti	up-regulation of blood vessel endothelial cell migration|upregulation of blood vessel endothelial cell migration|stimulation of blood vessel endothelial cell migration|activation of blood vessel endothelial cell migration|up regulation of blood vessel endothelial cell migration													biological_process											owl:Class	
GO:0003790	biolink:NamedThing	obsolete actin modulating activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	actin modulating activity				This term was made obsolete because it does not make sense.	GO:0030036				True				molecular_function											owl:Class	
GO:0042096	biolink:NamedThing	obsolete alpha-beta T cell receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	alpha-beta T cell receptor activity				This term was made obsolete because it describes a receptor type, and not an activity.	GO:0032394|GO:0032395|GO:0042605				True				molecular_function											owl:Class	
GO:0071833	biolink:NamedThing	peptide pheromone export involved in positive regulation of conjugation with cellular fusion	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.	got7fsn_ti							mah	2010-09-09T11:09:43Z						biological_process											owl:Class	
GO:1990560	biolink:NamedThing	obsolete DNA methyltransferase binding	OBSOLETE. Binding to a DNA methyltransferase.	got7fsn_ti	DNA methyltransferase binding				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-11-19T16:30:28Z		True				molecular_function											owl:Class	
GO:1905513	biolink:NamedThing	negative regulation of short-term synaptic potentiation	Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation.	got7fsn_ti	down regulation of synaptic facilitation|negative regulation of synaptic facilitation|down-regulation of short-term synaptic potentiation|downregulation of synaptic facilitation|down-regulation of synaptic facilitation|downregulation of short-term synaptic potentiation|inhibition of synaptic facilitation|inhibition of short-term synaptic potentiation|down regulation of short-term synaptic potentiation						hjd	2016-09-28T17:40:23Z						biological_process											owl:Class	
CHEBI:57895	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0036008	biolink:NamedThing	sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate.	got7fsn_ti							bf	2011-09-23T10:34:08Z				MetaCyc:SUCUTIL-PWY		biological_process											owl:Class	
GO:0009461	biolink:NamedThing	obsolete cytochrome c	OBSOLETE. A cytochrome containing heme bound to the protein by one or, more (commonly two) thioether bonds involving sulfhydryl groups of cysteine residues.	got7fsn_ti				GO:0008121	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1901213	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in heart development	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the development of the heart over time.	got7fsn_ti	regulation of global transcription from Pol II promoter involved in heart development|global transcription regulation from Pol II promoter involved in heart development|regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|regulation of transcription from Pol II promoter involved in dorsal vessel development|regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|regulation of global transcription from Pol II promoter involved in cardiac development|regulation of transcription from RNA polymerase II promoter involved in cardiac development|regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|regulation of transcription from Pol II promoter involved in heart development|regulation of global transcription from Pol II promoter involved in dorsal vessel development|global transcription regulation from Pol II promoter involved in dorsal vessel development|regulation of transcription from RNA polymerase II promoter, global involved in heart development|regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|regulation of transcription from Pol II promoter involved in cardiac development|global transcription regulation from Pol II promoter involved in cardiac development|regulation of transcription from RNA polymerase II promoter, global involved in cardiac development						rl	2012-07-31T07:26:45Z						biological_process											owl:Class	
GO:0007583	biolink:NamedThing	obsolete killer activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	killer activity				This term was made obsolete because it is ambiguous; 'killer activity' could refer to several different processes.	GO:0042267				True				biological_process											owl:Class	
GO:1903992	biolink:NamedThing	obsolete regulation of protein stabilization	OBSOLETE. Any process that modulates the frequency, rate or extent of protein stabilization.	got7fsn_ti	regulation of protein stabilization|regulation of lysosomal protein stabilization|regulation of protein stabilization activity|regulation of positive regulation of protein stability|regulation of protein sequestering				This term was made obsolete because it was created in error.	GO:0031647	pga	2015-03-05T13:32:49Z		True				biological_process											owl:Class	
GO:0051586	biolink:NamedThing	positive regulation of dopamine uptake involved in synaptic transmission	Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell.	got7fsn_ti	activation of dopamine uptake involved in synaptic transmission|positive regulation of dopamine import involved in synaptic transmission|up-regulation of dopamine uptake involved in synaptic transmission|upregulation of dopamine uptake involved in synaptic transmission|up regulation of dopamine uptake involved in synaptic transmission|stimulation of dopamine uptake involved in synaptic transmission													biological_process											owl:Class	
GO:0019947	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901227	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter involved in heart development	Any negative regulation of transcription from RNA polymerase II promoter that is involved in heart development.	got7fsn_ti	down regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of transcription from Pol II promoter involved in cardiac development|inhibition of global transcription from RNA polymerase II promoter involved in cardiac development|inhibition of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of global transcription from Pol II promoter involved in heart development|down regulation of global transcription from RNA polymerase II promoter involved in heart development|down regulation of global transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of global transcription from RNA polymerase II promoter involved in heart development|down-regulation of transcription from RNA polymerase II promoter involved in heart development|downregulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of transcription from Pol II promoter involved in heart development|inhibition of global transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of global transcription from RNA polymerase II promoter involved in heart development|negative regulation of global transcription from Pol II promoter involved in dorsal vessel development|negative regulation of transcription from Pol II promoter involved in dorsal vessel development|downregulation of global transcription from RNA polymerase II promoter involved in cardiac development|downregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of transcription from RNA polymerase II promoter involved in heart development|negative regulation of transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of transcription from RNA polymerase II promoter involved in cardiac development|downregulation of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|inhibition of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in heart development|negative regulation of global transcription from Pol II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in cardiac development						pr	2012-08-07T12:50:30Z						biological_process											owl:Class	
GO:0008100	biolink:NamedThing	obsolete lipophorin	OBSOLETE. Any member of the major class of lipid-transporting proteins found in the hemolymph of insects.	got7fsn_ti	lipophorin			GO:0005319	This term was made obsolete because it represents a class of gene products.					True				molecular_function											owl:Class	
GO:0010834	biolink:NamedThing	obsolete telomere maintenance via telomere shortening	OBSOLETE. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and shortening the telomeric DNA.	got7fsn_ti	telomere maintenance via telomere shortening				This term was made obsolete because it represents a phenotype.	GO:1903824				True				biological_process											owl:Class	
GO:1901001	biolink:NamedThing	negative regulation of response to salt stress	Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.	got7fsn_ti	inhibition of salinity response|down-regulation of response to ionic osmotic stress|down-regulation of salinity response|downregulation of response to ionic osmotic stress|inhibition of response to salt stress|down regulation of response to ionic osmotic stress|down-regulation of response to salt stress|negative regulation of response to ionic osmotic stress|downregulation of salinity response|inhibition of response to ionic osmotic stress|down regulation of salinity response|negative regulation of salinity response|downregulation of response to salt stress|down regulation of response to salt stress						dhl	2012-06-14T05:41:43Z						biological_process											owl:Class	
GO:1901436	biolink:NamedThing	positive regulation of toluene catabolic process	Any process that activates or increases the frequency, rate or extent of toluene catabolic process.	got7fsn_ti	activation of toluene breakdown|up-regulation of toluene breakdown|up-regulation of toluene degradation|upregulation of toluene degradation|up regulation of toluene catabolism|positive regulation of toluene degradation|activation of toluene degradation|up-regulation of toluene catabolic process|up regulation of toluene breakdown|positive regulation of toluene breakdown|up regulation of toluene degradation|positive regulation of toluene catabolism|upregulation of toluene catabolism|upregulation of toluene catabolic process|up regulation of toluene catabolic process|upregulation of toluene breakdown|up-regulation of toluene catabolism|activation of toluene catabolic process|activation of toluene catabolism						tt	2012-10-01T21:13:57Z						biological_process											owl:Class	
GO:0090054	biolink:NamedThing	regulation of silent mating-type cassette heterochromatin assembly	Any process that modulates the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.	got7fsn_ti	regulation of chromatin silencing at silent mating-type cassette	https://github.com/geneontology/go-ontology/issues/19112					tb	2009-08-07T10:52:59Z						biological_process											owl:Class	
GO:0008034	biolink:NamedThing	obsolete lipoprotein binding	OBSOLETE. Binding to a conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	got7fsn_ti	lipoprotein binding				This term was made obsolete because its text definition and implicit ontology-structure definition disagreed, and as a result the term had been used in annotations with more than one meaning.	GO:0071723|GO:0071813				True				molecular_function											owl:Class	
GO:2001022	biolink:NamedThing	positive regulation of response to DNA damage stimulus	Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.	got7fsn_ti	positive regulation of DNA damage response|positive regulation of cellular DNA damage response|positive regulation of cellular response to DNA damage stimulus|positive regulation of response to genotoxic stress						yaf	2011-08-19T10:20:33Z						biological_process											owl:Class	
GO:1900310	biolink:NamedThing	negative regulation of maltoheptaose metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process.	got7fsn_ti	negative regulation of maltoheptaose metabolism|down regulation of maltoheptaose metabolic process|down regulation of maltoheptaose metabolism|downregulation of maltoheptaose metabolism|inhibition of maltoheptaose metabolic process|down-regulation of maltoheptaose metabolic process|downregulation of maltoheptaose metabolic process|down-regulation of maltoheptaose metabolism|inhibition of maltoheptaose metabolism						tt	2012-04-05T07:58:58Z						biological_process											owl:Class	
GO:1904231	biolink:NamedThing	positive regulation of succinate dehydrogenase activity	Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity.	got7fsn_ti	up regulation of succinate:(acceptor) oxidoreductase activity|positive regulation of succinate:(acceptor) oxidoreductase activity|up-regulation of succinate:(acceptor) oxidoreductase activity|upregulation of fumaric hydrogenase activity|positive regulation of succinate oxidoreductase activity|up-regulation of succinate dehydrogenase activity|upregulation of fumarate dehydrogenase activity|activation of fumaric hydrogenase activity|up-regulation of fumarate reductase activity|activation of succinyl dehydrogenase activity|activation of fumarate dehydrogenase activity|activation of succinate oxidoreductase activity|activation of succinate dehydrogenase activity|upregulation of succinate:(acceptor) oxidoreductase activity|activation of succinate:acceptor oxidoreductase activity|up regulation of succinodehydrogenase activity|upregulation of succinic acid dehydrogenase activity|up-regulation of succinic acid dehydrogenase activity|activation of succinate:(acceptor) oxidoreductase activity|up regulation of succinyl dehydrogenase activity|upregulation of succinyl dehydrogenase activity|up regulation of fumarate dehydrogenase activity|positive regulation of fumarate reductase activity|upregulation of fumarate reductase activity|up regulation of succinate oxidoreductase activity|activation of fumarate reductase activity|positive regulation of succinate:acceptor oxidoreductase activity|upregulation of succinodehydrogenase activity|up regulation of fumaric hydrogenase activity|activation of succinic acid dehydrogenase activity|up regulation of fumarate reductase activity|up-regulation of succinate:acceptor oxidoreductase activity|up regulation of succinic acid dehydrogenase activity|up-regulation of succinodehydrogenase activity|up-regulation of succinate oxidoreductase activity|up regulation of succinate dehydrogenase activity|positive regulation of succinyl dehydrogenase activity|positive regulation of succinodehydrogenase activity|up-regulation of fumaric hydrogenase activity|upregulation of succinate oxidoreductase activity|up regulation of succinate:acceptor oxidoreductase activity|upregulation of succinate:acceptor oxidoreductase activity|up-regulation of fumarate dehydrogenase activity|up-regulation of succinyl dehydrogenase activity|upregulation of succinate dehydrogenase activity|activation of succinodehydrogenase activity|positive regulation of fumaric hydrogenase activity|positive regulation of succinic acid dehydrogenase activity|positive regulation of fumarate dehydrogenase activity						rl	2015-05-15T09:51:20Z						biological_process											owl:Class	
GO:0046106	biolink:NamedThing	thymine biosynthetic process	The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.	got7fsn_ti	thymine synthesis|thymine formation|thymine anabolism|thymine biosynthesis													biological_process											owl:Class	
GO:0033688	biolink:NamedThing	regulation of osteoblast proliferation	Any process that modulates the frequency, rate or extent of osteoblast proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0034173	biolink:NamedThing	positive regulation of toll-like receptor 11 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.	got7fsn_ti	positive regulation of toll-like receptor 11 signalling pathway|positive regulation of TLR11 signaling pathway													biological_process											owl:Class	
GO:1904469	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902605	biolink:NamedThing	heterotrimeric G-protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex.	got7fsn_ti	heterotrimeric G-protein complex formation|heterotrimeric G-protein GTPase activity assembly|heterotrimeric G-protein GTPase, beta-subunit formation|heterotrimeric G-protein GTPase, gamma-subunit formation|heterotrimeric G-protein GTPase activity formation|heterotrimeric G-protein GTPase, gamma-subunit assembly|heterotrimeric G-protein GTPase, alpha-subunit formation|heterotrimeric G-protein GTPase, beta-subunit assembly|heterotrimeric G-protein GTPase, alpha-subunit assembly						dph	2013-12-30T16:31:28Z						biological_process											owl:Class	
GO:1905070	biolink:NamedThing	anterior visceral endoderm cell migration	The orderly movement of an anterior visceral endoderm cell from one site to another.	got7fsn_ti							cls	2016-03-21T15:18:32Z						biological_process											owl:Class	
GO:0009789	biolink:NamedThing	positive regulation of abscisic acid-activated signaling pathway	Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.	got7fsn_ti	activation of abscisic acid mediated signaling|up-regulation of abscisic acid mediated signaling|up regulation of abscisic acid mediated signaling|upregulation of abscisic acid mediated signaling|positive regulation of abscisic acid mediated signaling pathway|stimulation of abscisic acid mediated signaling|positive regulation of abscisic acid mediated signalling													biological_process											owl:Class	
GO:0002856	biolink:NamedThing	negative regulation of natural killer cell mediated immune response to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.	got7fsn_ti	down regulation of natural killer cell mediated immune response to tumor cell|inhibition of natural killer cell mediated immune response to tumor cell|downregulation of natural killer cell mediated immune response to tumor cell|down-regulation of natural killer cell mediated immune response to tumor cell													biological_process											owl:Class	
GO:0090080	biolink:NamedThing	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.	got7fsn_ti	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signalling pathway						tb	2009-10-19T11:30:22Z						biological_process											owl:Class	
GO:2000573	biolink:NamedThing	positive regulation of DNA biosynthetic process	Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.	got7fsn_ti	positive regulation of DNA formation|positive regulation of DNA anabolism|positive regulation of DNA biosynthesis|positive regulation of DNA synthesis						yaf	2011-04-04T10:01:20Z						biological_process											owl:Class	
GO:0070868	biolink:NamedThing	obsolete heterochromatin organization involved in chromatin silencing	OBSOLETE. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing.	got7fsn_ti	heterochromatin organisation involved in chromatin silencing	https://github.com/geneontology/go-ontology/issues/22046			This term was obsoleted because it was not clearly defined, and used incorrectly.		mah	2009-08-20T12:45:52Z		True				biological_process											owl:Class	
GO:1905952	biolink:NamedThing	regulation of lipid localization	Any process that modulates the frequency, rate or extent of lipid localization.	got7fsn_ti	regulation of lipid localisation						rz	2017-02-21T12:12:22Z						biological_process											owl:Class	
GO:0006116	biolink:NamedThing	NADH oxidation	A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.	got7fsn_ti	reduced nicotinamide adenine dinucleotide dehydrogenation|NADH dehydrogenation|reduced nicotinamide adenine dinucleotide oxidation|reduced NAD oxidation|reduced NAD dehydrogenation|NAD (reduced) dehydrogenation|NAD (reduced) oxidation													biological_process											owl:Class	
GO:0044437	biolink:NamedThing	obsolete vacuolar part	OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.	got7fsn_ti	vacuole component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005773				True				cellular_component											owl:Class	
GO:1900506	biolink:NamedThing	regulation of iron-sulfur-molybdenum cofactor assembly	Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.	got7fsn_ti	regulation of FeMoco assembly|regulation of iron molybdenum cofactor assembly|regulation of iron molybdenum cofactor biosynthesis|regulation of iron molybdenum cofactor biosynthetic process|regulation of FeMoco biosynthetic process						tt	2012-05-02T04:02:16Z						biological_process											owl:Class	
GO:0008954	biolink:NamedThing	obsolete peptidoglycan synthetase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peptidoglycan synthetase activity				This term was made obsolete because it was not defined, is ambiguous, and has been used to annotate gene products with very different activities.	GO:0071972|GO:0008955				True				molecular_function											owl:Class	
GO:1902662	biolink:NamedThing	regulation of peptidyl-L-cysteine S-palmitoylation	Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.	got7fsn_ti	regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|regulation of peptidyl-cysteine S-palmitoylation|regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine						mm2	2014-01-29T11:33:09Z						biological_process											owl:Class	
GO:0003808	biolink:NamedThing	obsolete protein C (activated) activity	OBSOLETE. Catalysis of the degradation of blood coagulation factors Va and VIIIa.	got7fsn_ti	protein Ca|blood-coagulation factor XIVa|protein C (activated) activity|autoprothrombin IIA activity|autoprothrombin II-A|activated protein C|GSAPC|activated blood coagulation factor XIV activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0033706	biolink:NamedThing	obsolete quinate/shikimate dehydrogenase activity	OBSOLETE. Catalysis of the reactions: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+, and shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+.	got7fsn_ti	quinate/shikimate dehydrogenase activity|L-quinate:NAD(P)+ 3-oxidoreductase activity|YdiB				This term was made obsolete because it represents four reactions, and should be four separate terms.	GO:0052734|GO:0030266|GO:0004764|GO:0052733				True				molecular_function											owl:Class	
GO:0019530	biolink:NamedThing	taurine metabolic process	The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.	got7fsn_ti	taurine metabolism													biological_process											owl:Class	
GO:0031420	biolink:NamedThing	alkali metal ion binding	Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen.	got7fsn_ti														molecular_function											owl:Class	
GO:1903930	biolink:NamedThing	regulation of pyrimidine-containing compound salvage	Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage.	got7fsn_ti	regulation of pyrimidine salvage						al	2015-02-12T14:09:05Z						biological_process											owl:Class	
GO:0032479	biolink:NamedThing	regulation of type I interferon production	Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	got7fsn_ti	regulation of type I IFN production													biological_process											owl:Class	
GO:0002082	biolink:NamedThing	regulation of oxidative phosphorylation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.	got7fsn_ti	OXPHOS													biological_process											owl:Class	
GO:0033359	biolink:NamedThing	lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate	The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.	got7fsn_ti	lysine formation via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine synthesis via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine biosynthetic process via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate|lysine anabolism via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine biosynthesis via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate											MetaCyc:DAPLYSINESYN-PWY		biological_process											owl:Class	
GO:0052137	biolink:NamedThing	obsolete aerotaxis in host	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	aerotaxis within host	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1905873	biolink:NamedThing	positive regulation of protein localization to cell leading edge	Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge.	got7fsn_ti	upregulation of protein localisation to cell leading edge|positive regulation of protein localization in cell leading edge|up-regulation of protein localisation to cell leading edge|activation of protein localisation to cell leading edge|up regulation of protein localization to cell leading edge|positive regulation of protein localisation to cell leading edge|activation of protein localisation in cell leading edge|up regulation of protein localisation to cell leading edge|up-regulation of protein localization to cell leading edge|activation of protein localization to cell leading edge|up regulation of protein localization in cell leading edge|up-regulation of protein localisation in cell leading edge|positive regulation of protein localisation in cell leading edge|upregulation of protein localization to cell leading edge|activation of protein localization in cell leading edge|upregulation of protein localisation in cell leading edge|up-regulation of protein localization in cell leading edge|upregulation of protein localization in cell leading edge|up regulation of protein localisation in cell leading edge						sl	2017-01-27T19:35:13Z						biological_process											owl:Class	
GO:1900227	biolink:NamedThing	positive regulation of NLRP3 inflammasome complex assembly	Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly.	got7fsn_ti	activation of NLRP3 inflammasome activation|up-regulation of NLRP3 inflammasome complex assembly|upregulation of NALP3 inflammasome complex assembly|activation of NLRP3 inflammasome complex assembly|up-regulation of NALP3 inflammasome complex assembly|up regulation of NLRP3 inflammasome complex assembly|upregulation of NLRP3 inflammasome complex assembly|activation of NALP3 inflammasome complex assembly|up-regulation of NLRP3 inflammasome activation|positive regulation of NLRP3 inflammasome activation|up regulation of NLRP3 inflammasome activation|up regulation of NALP3 inflammasome complex assembly|positive regulation of NALP3 inflammasome complex assembly|upregulation of NLRP3 inflammasome activation						jl	2012-03-22T04:18:32Z						biological_process											owl:Class	
GO:1901014	biolink:NamedThing	3alpha(S)-strictosidine catabolic process	The chemical reactions and pathways resulting in the breakdown of 3alpha(S)-strictosidine.	got7fsn_ti	3alpha(S)-strictosidine degradation|3alpha(S)-strictosidine catabolism|3alpha(S)-strictosidine breakdown						yaf	2012-06-15T10:47:19Z						biological_process											owl:Class	
GO:0019940	biolink:NamedThing	obsolete SUMO-dependent protein catabolic process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	SUMO-dependent protein catabolism|SUMO-dependent protein breakdown|SUMO-dependent protein degradation|SUMO-dependent protein catabolic process				This term was made obsolete because it does not reflect an accurate biological process, as sumoylation of a protein does not lead to catabolism of that protein.	GO:0016925|GO:0016926				True				biological_process											owl:Class	
GO:0015957	biolink:NamedThing	bis(5'-nucleosidyl) oligophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.	got7fsn_ti	bis(5'-nucleosidyl) oligophosphate biosynthesis|bis(5'-nucleosidyl) oligophosphate anabolism|bis(5'-nucleosidyl) oligophosphate synthesis|bis(5'-nucleosidyl) oligophosphate formation													biological_process											owl:Class	
GO:1905485	biolink:NamedThing	positive regulation of motor neuron migration	Any process that activates or increases the frequency, rate or extent of motor neuron migration.	got7fsn_ti	upregulation of motor neuron migration|up regulation of motor neuron migration|up-regulation of motor neuron migration|activation of motor neuron migration						hbye	2016-09-23T12:50:19Z						biological_process											owl:Class	
GO:0070963	biolink:NamedThing	positive regulation of neutrophil mediated killing of gram-negative bacterium	Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.	got7fsn_ti	up regulation of neutrophil mediated killing of gram-negative bacterium|activation of neutrophil mediated killing of gram-negative bacterium|stimulation of neutrophil mediated killing of gram-negative bacterium|up-regulation of neutrophil mediated killing of gram-negative bacterium|upregulation of neutrophil mediated killing of gram-negative bacterium						mah	2009-10-01T02:28:49Z						biological_process											owl:Class	
PO:0009088	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905890	biolink:NamedThing	regulation of cellular response to very-low-density lipoprotein particle stimulus	Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.	got7fsn_ti	regulation of cellular response to VLDL particle stimulus						bc	2017-02-01T10:09:16Z						biological_process											owl:Class	
GO:0071505	biolink:NamedThing	response to mycophenolic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.	got7fsn_ti	response to mycophenolate						mah	2009-12-18T03:46:00Z						biological_process											owl:Class	
GO:0051543	biolink:NamedThing	regulation of elastin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.	got7fsn_ti														biological_process											owl:Class	
GO:1901033	biolink:NamedThing	positive regulation of response to reactive oxygen species	Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species.	got7fsn_ti	up regulation of response to ROS|up regulation of response to reactive oxidative species|up-regulation of response to AOS|up regulation of response to AOS|up regulation of response to reactive oxygen intermediate|activation of response to reactive oxygen species|positive regulation of response to AOS|activation of response to ROI|positive regulation of response to ROS|upregulation of response to active oxygen species|activation of response to reactive oxidative species|positive regulation of response to reactive oxidative species|up regulation of response to ROI|positive regulation of response to reactive oxygen intermediate|up-regulation of response to ROI|upregulation of response to AOS|positive regulation of response to ROI|upregulation of response to reactive oxidative species|up-regulation of response to active oxygen species|activation of response to reactive oxygen intermediate|positive regulation of response to active oxygen species|up regulation of response to active oxygen species|upregulation of response to reactive oxygen species|up-regulation of response to ROS|activation of response to AOS|activation of response to ROS|upregulation of response to reactive oxygen intermediate|upregulation of response to ROI|activation of response to active oxygen species|up regulation of response to reactive oxygen species|up-regulation of response to reactive oxidative species|up-regulation of response to reactive oxygen species|up-regulation of response to reactive oxygen intermediate|upregulation of response to ROS						kmv	2012-06-20T07:47:35Z						biological_process											owl:Class	
GO:1901697	biolink:NamedThing	olivetolic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of olivetolic acid.	got7fsn_ti	olivetolic acid synthesis|olivetolic acid biosynthesis|olivetolic acid formation|olivetolic acid anabolism						ms	2012-12-13T08:07:51Z						biological_process											owl:Class	
GO:0048295	biolink:NamedThing	positive regulation of isotype switching to IgE isotypes	Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.	got7fsn_ti	positive regulation of class switch recombination to IgE isotypes|positive regulation of class switching to IgE isotypes|stimulation of isotype switching to IgE isotypes|up-regulation of isotype switching to IgE isotypes|upregulation of isotype switching to IgE isotypes|activation of isotype switching to IgE isotypes|positive regulation of isotype switch recombination to IgE isotypes|up regulation of isotype switching to IgE isotypes													biological_process											owl:Class	
GO:1904990	biolink:NamedThing	regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.	got7fsn_ti	regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|regulation of dopamine receptor, adenylate cyclase inhibiting pathway|regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway						kmv	2016-02-29T22:42:16Z						biological_process											owl:Class	
GO:0002830	biolink:NamedThing	positive regulation of type 2 immune response	Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.	got7fsn_ti	positive regulation of T-helper 2 type immune response|stimulation of type 2 immune response|up regulation of type 2 immune response|upregulation of type 2 immune response|activation of type 2 immune response|up-regulation of type 2 immune response|positive regulation of Th2 immune response													biological_process											owl:Class	
GO:1903332	biolink:NamedThing	regulation of protein folding	Any process that modulates the frequency, rate or extent of protein folding.	got7fsn_ti	regulation of chaperone activity|regulation of glycoprotein-specific chaperone activity|regulation of co-chaperonin activity|regulation of chaperonin ATPase activity|regulation of protein complex assembly, multichaperone pathway|regulation of chaperonin-mediated tubulin folding|regulation of beta-tubulin folding|regulation of co-chaperone activity|regulation of alpha-tubulin folding|regulation of non-chaperonin molecular chaperone ATPase activity						vw	2014-08-18T13:14:34Z						biological_process											owl:Class	
GO:0042666	biolink:NamedThing	negative regulation of ectodermal cell fate specification	Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell.	got7fsn_ti	suppression of ectoderm cell fate|downregulation of ectodermal cell fate specification|down-regulation of ectodermal cell fate specification|down regulation of ectodermal cell fate specification|negative regulation of ectoderm cell fate specification|inhibition of ectodermal cell fate specification|suppression of ectodermal cell fate													biological_process											owl:Class	
GO:0061972	biolink:NamedThing	dermal bone morphogenesis	The process in which bone which forms superficially in the organism are generated and organized.	got7fsn_ti							dph	2018-02-12T18:16:21Z						biological_process											owl:Class	
GO:0034766	biolink:NamedThing	negative regulation of ion transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.	got7fsn_ti	inhibition of transmembrane ion transport|down regulation of transmembrane ion transport|negative regulation of transmembrane ion transport|downregulation of transmembrane ion transport|down-regulation of transmembrane ion transport|negative regulation of ion membrane transport													biological_process											owl:Class	
GO:0014918	biolink:NamedThing	obsolete positive regulation of natriuresis by pressure natriuresis	OBSOLETE. The process in which pressure natriuresis increases rate of natriuresis.	got7fsn_ti	positive regulation of natriuresis by pressure natriuresis			GO:0035819	This term was made obsolete because its definition was inaccurate.					True				biological_process											owl:Class	
GO:1900407	biolink:NamedThing	regulation of cellular response to oxidative stress	Any process that modulates the frequency, rate or extent of cellular response to oxidative stress.	got7fsn_ti	regulation of adaptive response to oxidative stress						mah	2012-04-20T03:30:52Z						biological_process											owl:Class	
GO:0051853	biolink:NamedThing	obsolete induction in symbiont of tumor, nodule, or growth	OBSOLETE. The process by which an associated organism causes the formation of an abnormal mass of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction in symbiont of tumor, nodule, or growth	https://github.com/geneontology/go-ontology/issues/18605			This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
GO:0061216	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in mesonephros development	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state.	got7fsn_ti							dph	2010-08-17T03:32:27Z						biological_process											owl:Class	
GO:1905353	biolink:NamedThing	ciliary transition fiber assembly	The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber.	got7fsn_ti	cilium transition fibre assembly|ciliary transition fibre assembly|ciliary transition fiber formation|cilium transition fiber assembly|cilium transition fibre formation|distal appendage of mother centriole formation|ciliary transition fibre formation|distal appendage of basal body formation|distal appendage of centriole assembly|cilium transition fiber formation|cilial transition fiber formation|distal appendage of centriole formation|centriolar distal appendage assembly|cilial transition fiber assembly|cilial transition fibre formation|cilial transition fibre assembly|distal appendage of basal body assembly|distal appendage of mother centriole assembly|centriolar distal appendage formation						pr	2016-08-05T14:01:32Z						biological_process											owl:Class	
GO:0005779	biolink:NamedThing	integral component of peroxisomal membrane	The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to peroxisomal membrane													cellular_component											owl:Class	
GO:0005307	biolink:NamedThing	choline:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in).	got7fsn_ti	sodium/choline symporter activity													molecular_function											owl:Class	
GO:1902401	biolink:NamedThing	obsolete detection of stimulus involved in mitotic DNA damage checkpoint	OBSOLETE. Any detection of stimulus that is involved in mitotic DNA damage checkpoint.	got7fsn_ti	stimulus sensing involved in mitotic DNA damage checkpoint|stimulus detection involved in mitotic DNA damage checkpoint|perception of stimulus involved in mitotic DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		jl	2013-09-12T12:07:12Z		True				biological_process											owl:Class	
GO:0051941	biolink:NamedThing	regulation of amino acid uptake involved in synaptic transmission	Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.	got7fsn_ti	regulation of amino acid neurotransmitter uptake|regulation of amino acid neurotransmitter reuptake|regulation of amino acid uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0071627	biolink:NamedThing	integral component of fungal-type vacuolar membrane	The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to fungal-type vacuolar membrane						mah	2010-02-10T03:45:23Z						cellular_component											owl:Class	
GO:1905075	biolink:NamedThing	positive regulation of tight junction disassembly	Any process that activates or increases the frequency, rate or extent of tight junction disassembly.	got7fsn_ti	upregulation of tight junction disassembly|up-regulation of occluding cell junction disassembly|activation of occluding cell junction disassembly|up regulation of tight junction disassembly|positive regulation of occluding junction disassembly|up-regulation of tight junction disassembly|upregulation of occluding cell junction disassembly|activation of occluding junction disassembly|positive regulation of occluding cell junction disassembly|up regulation of occluding cell junction disassembly|activation of tight junction disassembly						rl	2016-03-23T19:33:10Z						biological_process											owl:Class	
GO:1903485	biolink:NamedThing	obsolete positive regulation of maintenance of mitotic actomyosin contractile ring localization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.	got7fsn_ti	activation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|up regulation of maintenance of mitotic actomyosin contractile ring localization|activation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of maintenance of mitotic actomyosin contractile ring localization|up regulation of cytokinetic ring anchoring involved in mitotic cell cycle|activation of cytokinetic ring anchoring involved in mitotic cell cycle|upregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|up regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of mitotic actomyosin contractile ring localization|up-regulation of cytokinetic ring anchoring involved in mitotic cell cycle|activation of maintenance of mitotic actomyosin contractile ring localization|activation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|positive regulation of cytokinetic ring anchoring involved in mitotic cell cycle|up regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of cytokinetic ring anchoring involved in mitotic cell cycle				The reason for obsoletion is that this term represents a GO-CAM model.		vw	2014-09-23T16:12:37Z		True				biological_process											owl:Class	
GO:1990721	biolink:NamedThing	obsolete prostatic acid phosphatase complex	OBSOLETE. A protein complex that is capable of dephosphorylation of alky, aryl and acyl orthophosphate monoesters and phosphorylated proteins. Optimal activity in acidic environment (pH 4-6). In mammals it consists of a homodimer of ACPP.	got7fsn_ti	PAP complex|prostatic acid phosphatase complex|ACPP homodimer complex				This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2015-04-01T09:43:14Z		True				cellular_component											owl:Class	
GO:0039525	biolink:NamedThing	modulation by virus of host chromatin organization	Any process in which a virus effects a change in the organization of chromatin in the host.	got7fsn_ti	regulation by virus of host chromatin organization|modulation by virus of host chromatin organisation|modulation of host chromatin by virus|modulation of host chromatin structure by virus						bf	2011-06-22T05:11:13Z						biological_process											owl:Class	
GO:0048216	biolink:NamedThing	negative regulation of Golgi vesicle fusion to target membrane	Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane.	got7fsn_ti	downregulation of Golgi vesicle fusion to target membrane|down regulation of Golgi vesicle fusion to target membrane|inhibition of Golgi vesicle fusion to target membrane|down-regulation of Golgi vesicle fusion to target membrane													biological_process											owl:Class	
GO:0035021	biolink:NamedThing	negative regulation of Rac protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.	got7fsn_ti	downregulation of Rac protein signal transduction|down regulation of Rac protein signal transduction|inhibition of Rac protein signal transduction|down-regulation of Rac protein signal transduction													biological_process											owl:Class	
GO:0042174	biolink:NamedThing	negative regulation of sporulation resulting in formation of a cellular spore	Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation.	got7fsn_ti	inhibition of sporulation|down-regulation of sporulation|down regulation of sporulation|downregulation of sporulation													biological_process											owl:Class	
GO:1905177	biolink:NamedThing	tracheary element differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element.	got7fsn_ti							tb	2016-05-04T22:14:33Z						biological_process											owl:Class	
GO:2001063	biolink:NamedThing	glucomannan binding	Binding to glucomannan.	got7fsn_ti							jl	2011-09-14T10:29:45Z						molecular_function											owl:Class	
GO:1902054	biolink:NamedThing	negative regulation of neosartoricin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process.	got7fsn_ti	negative regulation of neosartoricin synthesis|down regulation of neosartoricin biosynthetic process|inhibition of neosartoricin biosynthesis|negative regulation of neosartoricin biosynthesis|down-regulation of neosartoricin biosynthesis|down-regulation of neosartoricin formation|inhibition of neosartoricin anabolism|downregulation of neosartoricin biosynthesis|inhibition of neosartoricin formation|down-regulation of neosartoricin anabolism|down regulation of neosartoricin biosynthesis|down regulation of neosartoricin synthesis|downregulation of neosartoricin formation|inhibition of neosartoricin biosynthetic process|down-regulation of neosartoricin synthesis|negative regulation of neosartoricin anabolism|inhibition of neosartoricin synthesis|down-regulation of neosartoricin biosynthetic process|downregulation of neosartoricin synthesis|negative regulation of neosartoricin formation|downregulation of neosartoricin biosynthetic process|down regulation of neosartoricin formation|downregulation of neosartoricin anabolism|down regulation of neosartoricin anabolism						di	2013-04-11T15:46:15Z						biological_process											owl:Class	
GO:0006046	biolink:NamedThing	N-acetylglucosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.	got7fsn_ti	N-acetylglucosamine breakdown|N-acetylglucosamine degradation|N-acetylglucosamine catabolism													biological_process											owl:Class	
GO:0019593	biolink:NamedThing	mannitol biosynthetic process	The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.	got7fsn_ti	mannitol synthesis|mannitol formation|mannitol biosynthesis|mannitol anabolism											MetaCyc:PWY-3881		biological_process											owl:Class	
GO:1904969	biolink:NamedThing	slow muscle cell migration	The orderly movement of a slow muscle cell from one site to another.	got7fsn_ti	slow-twitch muscle cell migration				The directional migration of a slow muscle cell from one site to another within the embryo.		ymb	2016-02-16T21:20:11Z						biological_process											owl:Class	
GO:0035950	biolink:NamedThing	obsolete regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of oligopeptide transport, by regulation of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of oligopeptide transport by regulation of transcription from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
CL:0000150	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900720	biolink:NamedThing	negative regulation of uterine smooth muscle relaxation	Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation.	got7fsn_ti	negative regulation of smooth muscle relaxation of the uterus|down regulation of uterine smooth muscle relaxation|down-regulation of smooth muscle relaxation of the uterus|downregulation of uterine smooth muscle relaxation|downregulation of smooth muscle relaxation of the uterus|inhibition of uterine smooth muscle relaxation|down regulation of smooth muscle relaxation of the uterus|inhibition of smooth muscle relaxation of the uterus|down-regulation of uterine smooth muscle relaxation						jl	2012-05-24T03:12:49Z						biological_process											owl:Class	
GO:0045212	biolink:NamedThing	obsolete neurotransmitter receptor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitter receptors.	got7fsn_ti	neurotransmitter receptor synthesis|neurotransmitter receptor formation|neurotransmitter receptor biosynthesis|neurotransmitter receptor anabolism	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1905908	biolink:NamedThing	positive regulation of amyloid fibril formation	Any process that activates or increases the frequency, rate or extent of amyloid fibril formation.	got7fsn_ti	positive regulation of amyloid structure formation|activation of amyloid structure formation|up regulation of amyloid structure assembly|activation of amyloid fibril assembly|up-regulation of amyloid fibril formation|activation of amyloid fibril formation|up-regulation of amyloid structure formation|activation of amyloid structure assembly|upregulation of amyloid fibril formation|upregulation of amyloid fibril assembly|upregulation of amyloid structure assembly|positive regulation of amyloid structure assembly|upregulation of amyloid structure formation|up regulation of amyloid structure formation|up regulation of amyloid fibril assembly|positive regulation of amyloid fibril assembly|up regulation of amyloid fibril formation|up-regulation of amyloid fibril assembly|up-regulation of amyloid structure assembly				Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases  (PMID:22817896).		bc	2017-02-03T15:44:05Z						biological_process											owl:Class	
GO:0009490	biolink:NamedThing	obsolete mononuclear iron electron carrier	OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system.	got7fsn_ti	mononuclear iron electron carrier			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:0046390	biolink:NamedThing	ribose phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.	got7fsn_ti	ribose phosphate biosynthesis|ribose phosphate anabolism|ribose phosphate formation|ribose phosphate synthesis													biological_process											owl:Class	
GO:1903289	biolink:NamedThing	obsolete regulation of ATP catabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of ATP catabolic process.	got7fsn_ti	regulation of ATP catabolism|regulation of ATP degradation|regulation of ATP breakdown|regulation of ATP hydrolysis				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0043462	rl	2014-08-11T14:36:39Z		True				biological_process											owl:Class	
GO:0002670	biolink:NamedThing	regulation of B cell anergy	Any process that modulates the frequency, rate, or extent of B cell anergy.	got7fsn_ti	regulation of B lymphocyte anergy|regulation of B-lymphocyte anergy|regulation of B-cell anergy													biological_process											owl:Class	
GO:1903584	biolink:NamedThing	regulation of histone deubiquitination	Any process that modulates the frequency, rate or extent of histone deubiquitination.	got7fsn_ti	regulation of histone deubiquitylation|regulation of histone deubiquitinylation						lb	2014-11-03T13:47:26Z						biological_process											owl:Class	
GO:0031376	biolink:NamedThing	obsolete cytosolic type II fatty acid synthase complex	OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the cytosol.	got7fsn_ti	cytosolic type II FAS complex|cytosolic type II fatty acid synthase complex									True				cellular_component											owl:Class	
GO:0060917	biolink:NamedThing	regulation of (1->6)-beta-D-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.	got7fsn_ti	regulation of 1,6-beta-glucan biosynthetic process						dph	2009-09-18T02:15:01Z						biological_process											owl:Class	
GO:1905827	biolink:NamedThing	positive regulation of selenocysteine metabolic process	Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process.	got7fsn_ti	upregulation of selenocysteine metabolism|activation of selenocysteine metabolism|up regulation of selenocysteine metabolic process|positive regulation of selenocysteine metabolism|up regulation of selenocysteine metabolism|activation of selenocysteine metabolic process|up-regulation of selenocysteine metabolic process|upregulation of selenocysteine metabolic process|up-regulation of selenocysteine metabolism						sl	2017-01-16T19:01:50Z						biological_process											owl:Class	
GO:0016173	biolink:NamedThing	obsolete ice nucleation inhibitor activity	OBSOLETE. Inhibits the formation of ice crystals.	got7fsn_ti	ice nucleation inhibitor activity				This term was made obsolete because it refers to a biological process.	GO:0050826|GO:0042309|GO:0050825				True				molecular_function											owl:Class	
GO:0036206	biolink:NamedThing	obsolete regulation of histone gene expression	OBSOLETE. Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.	got7fsn_ti	regulation of expression of histone-encoding gene				This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0006357	bf	2012-04-24T05:01:28Z		True				biological_process											owl:Class	
GO:0000739	biolink:NamedThing	obsolete DNA strand annealing activity	OBSOLETE. Facilitates the base-pairing of complementary single-stranded DNA.	got7fsn_ti	DNA strand annealing activity				This term was made obsolete because it describes a process and not an activity.	GO:0036292|GO:0036310				True				molecular_function											owl:Class	
GO:0023007	biolink:NamedThing	obsolete ligand binding to T cell receptor	OBSOLETE. Binding of a diffusible ligand to a T cell receptor as part of a signaling process.	got7fsn_ti	ligand binding to T cell receptor				This term was made obsolete because it is describing a binding molecular function.	GO:0042101|GO:0050852|GO:0042608		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1902345	biolink:NamedThing	positive regulation of maltose transport	Any process that activates or increases the frequency, rate or extent of maltose transport.	got7fsn_ti	up-regulation of maltose transport|activation of maltose transport|up regulation of maltose transport|upregulation of maltose transport						dph	2013-08-01T17:16:34Z						biological_process											owl:Class	
GO:0016467	biolink:NamedThing	obsolete hydrogen-translocating F-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria.	got7fsn_ti	proton-translocating F-type ATPase activity|F1-ATPase activity|ATP synthase|hydrogen-translocating F-type ATPase activity				This term was made obsolete because it represents a gene product.	GO:0046961|GO:0046933				True				molecular_function											owl:Class	
GO:1900835	biolink:NamedThing	negative regulation of emericellin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process.	got7fsn_ti	downregulation of emericellin biosynthetic process|down regulation of emericellin biosynthetic process|down-regulation of emericellin biosynthetic process						di	2012-06-07T09:32:24Z						biological_process											owl:Class	
GO:0036114	biolink:NamedThing	medium-chain fatty-acyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.	got7fsn_ti	medium-chain fatty-acyl-CoA catabolism|medium-chain fatty-acyl-CoA degradation|medium-chain fatty-acyl-CoA breakdown						bf	2012-02-15T11:23:16Z						biological_process											owl:Class	
GO:1902306	biolink:NamedThing	negative regulation of sodium ion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.	got7fsn_ti	down-regulation of sodium ion membrane transport|down regulation of sodium ion transmembrane transport|down regulation of sodium ion membrane transport|downregulation of sodium ion membrane transport|downregulation of sodium ion transmembrane transport|inhibition of sodium ion transmembrane transport|down-regulation of sodium ion transmembrane transport|negative regulation of sodium ion membrane transport|inhibition of sodium ion membrane transport						rl	2013-07-18T13:34:01Z						biological_process											owl:Class	
GO:0070403	biolink:NamedThing	NAD+ binding	Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.	got7fsn_ti	oxidized nicotinamide adenine dinucleotide binding|NAD binding|oxidized NAD binding|NAD (oxidized) binding													molecular_function											owl:Class	
GO:0061816	biolink:NamedThing	proteaphagy	The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles.	got7fsn_ti							dph	2016-12-01T20:21:28Z						biological_process											owl:Class	
GO:1904506	biolink:NamedThing	negative regulation of telomere maintenance in response to DNA damage	Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.	got7fsn_ti	inhibition of telomere maintenance in response to DNA damage|down regulation of DNA damage response, telomere maintenance|negative regulation of DNA damage response, telomere maintenance|downregulation of DNA damage response, telomere maintenance|down regulation of telomere maintenance in response to DNA damage|down-regulation of DNA damage response, telomere maintenance|down-regulation of telomere maintenance in response to DNA damage|inhibition of DNA damage response, telomere maintenance|downregulation of telomere maintenance in response to DNA damage						nc	2015-07-24T16:06:02Z						biological_process											owl:Class	
GO:1903985	biolink:NamedThing	regulation of intestinal D-glucose absorption	Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption.	got7fsn_ti							als	2015-03-04T10:07:55Z						biological_process											owl:Class	
GO:0097755	biolink:NamedThing	obsolete positive regulation of blood vessel diameter	OBSOLETE. Any process that increases the diameter of blood vessels.	got7fsn_ti	positive regulation of vasodilation				This term was obsoleted because it corresponded to an existing term, GO:0042311 ; vasodilation.		pr	2017-02-08T15:33:21Z		True				biological_process											owl:Class	
GO:0008553	biolink:NamedThing	P-type proton-exporting transporter activity	Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.	got7fsn_ti	proton transport ATPase activity|hydrogen-/sodium-translocating ATPase activity|H+-exporting ATPase activity|H+-transporting ATPase|proton-translocating ATPase activity|proton-exporting ATPase activity, phosphorylative mechanism|P-type H(+)-exporting ATPase activity|hydrogen-exporting ATPase activity, phosphorylative mechanism|proton-transporting ATPase activity|hydrogen-exporting ATPase activity|hydrogen exporting ATPase activity, phosphorylative mechanism|proton-exporting ATPase activity|H(+)-transporting ATPase activity						bf	2013-09-30T16:56:16Z			GO:0036442	RHEA:20852|EC:7.1.2.1|MetaCyc:3.6.3.6-RXN		molecular_function											owl:Class	
GO:0016658	biolink:NamedThing	obsolete oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor				This term was made obsolete because it was a grouping term taken from EC that no longer has any functions associated with it.	GO:0008752|GO:0042602				True				molecular_function											owl:Class	
GO:0051512	biolink:NamedThing	positive regulation of unidimensional cell growth	Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.	got7fsn_ti	upregulation of unidimensional cell growth|up regulation of unidimensional cell growth|positive regulation of cell elongation|activation of unidimensional cell growth|up-regulation of unidimensional cell growth|stimulation of unidimensional cell growth													biological_process											owl:Class	
GO:1904716	biolink:NamedThing	positive regulation of chaperone-mediated autophagy	Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy.	got7fsn_ti	up regulation of chaperone-mediated autophagy|up-regulation of chaperone-mediated autophagy|activation of chaperone-mediated autophagy|positive regulation of CMA|upregulation of chaperone-mediated autophagy|upregulation of CMA|up regulation of CMA|up-regulation of CMA|activation of CMA						pad	2015-10-06T08:49:15Z						biological_process											owl:Class	
GO:0010750	biolink:NamedThing	positive regulation of nitric oxide mediated signal transduction	Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).	got7fsn_ti	positive regulation of nitric oxide-mediated signal transduction													biological_process											owl:Class	
GO:0046023	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle.	got7fsn_ti	regulation of transcription from RNA polymerase III promoter during mitosis|mitotic regulation of transcription from Pol III promoter|regulation of transcription from Pol III promoter, mitotic	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0006359|GO:0044772				True				biological_process											owl:Class	
GO:0004289	biolink:NamedThing	obsolete subtilase activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	subtilase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0020013	biolink:NamedThing	modulation by symbiont of host erythrocyte aggregation	Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.	got7fsn_ti	rosetting				Please note that this term does not refer to the in vitro assay called erythrocyte rosetting.							Wikipedia:Rosetting		biological_process											owl:Class	
GO:0004286	biolink:NamedThing	obsolete proprotein convertase 2 activity	OBSOLETE. Catalysis of the release of protein hormones and neuropeptides from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond.	got7fsn_ti	NEC 2 activity|prohormone convertase II activity|proprotein convertase 2 activity|PC2 activity|neuroendocrine convertase 2 activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:2000781	biolink:NamedThing	positive regulation of double-strand break repair	Any process that activates or increases the frequency, rate or extent of double-strand break repair.	got7fsn_ti							bf	2011-06-23T09:28:13Z						biological_process											owl:Class	
GO:0070600	biolink:NamedThing	fungal-type cell wall (1->3)-alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.	got7fsn_ti	fungal-type cell wall alpha-1,3-glucan biosynthesis|fungal-type cell wall 1,3-alpha-glucan formation|fungal-type cell wall 1,3-alpha-glucan biosynthesis|fungal-type cell wall 1,3-alpha-glucan anabolism|fungal-type cell wall alpha-1,3-glucan anabolism|fungal-type cell wall 1,3-alpha-glucan biosynthetic process|fungal-type cell wall alpha-1,3-glucan synthesis|fungal-type cell wall 1,3-alpha-glucan synthesis|fungal-type cell wall alpha-1,3-glucan biosynthetic process|fungal-type cell wall alpha-1,3-glucan formation						mah	2009-04-28T04:09:48Z						biological_process											owl:Class	
GO:1903427	biolink:NamedThing	negative regulation of reactive oxygen species biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process.	got7fsn_ti	negative regulation of reactive oxygen species generation|negative regulation of reactive oxygen species biosynthesis|negative regulation of ROS formation|downregulation of reactive oxygen species anabolism|downregulation of reactive oxygen species biosynthetic process|down regulation of reactive oxygen species formation|downregulation of ROS formation|inhibition of ROS generation|inhibition of ROS formation|down regulation of reactive oxygen species synthesis|inhibition of reactive oxygen species biosynthetic process|inhibition of reactive oxygen species anabolism|downregulation of reactive oxygen species synthesis|down-regulation of reactive oxygen species formation|down-regulation of reactive oxygen species anabolism|inhibition of reactive oxygen species formation|down-regulation of ROS formation|downregulation of reactive oxygen species formation|inhibition of reactive oxygen species generation|down-regulation of ROS generation|downregulation of reactive oxygen species biosynthesis|prevention of ROS generation|negative regulation of reactive oxygen species anabolism|down-regulation of reactive oxygen species generation|downregulation of reactive oxygen species generation|down regulation of ROS formation|inhibition of reactive oxygen species biosynthesis|downregulation of ROS generation|down regulation of reactive oxygen species biosynthesis|negative regulation of reactive oxygen species formation|down regulation of reactive oxygen species generation|down-regulation of reactive oxygen species biosynthetic process|down regulation of reactive oxygen species biosynthetic process|negative regulation of reactive oxygen species synthesis|inhibition of reactive oxygen species synthesis|down regulation of ROS generation|down regulation of reactive oxygen species anabolism|down-regulation of reactive oxygen species biosynthesis|negative regulation of ROS generation|down-regulation of reactive oxygen species synthesis						bf	2014-09-11T10:01:56Z						biological_process											owl:Class	
GO:0098559	biolink:NamedThing	cytoplasmic side of early endosome membrane	The side (leaflet) of the early endosome membrane that faces the cytoplasm.	got7fsn_ti	external leaflet of early endosome membrane|external side of early endosome membrane				In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane.									cellular_component											owl:Class	
GO:0010989	biolink:NamedThing	negative regulation of low-density lipoprotein particle clearance	Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							tb	2009-06-01T12:15:07Z						biological_process											owl:Class	
GO:0039510	biolink:NamedThing	obsolete suppression by virus of host ATP-dependent RNA helicase activity	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ATP-dependent RNA helicase activity.	got7fsn_ti	inhibition by virus of host ATP-dependent RNA helicase activity|downregulation by virus of host ATP-dependent RNA helicase activity|negative regulation by virus of host ATP-dependent RNA helicase activity|down-regulation by virus of host ATP-dependent RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.		bf	2011-06-16T02:11:00Z		True				biological_process											owl:Class	
GO:1901056	biolink:NamedThing	trimethylenediamine catabolic process	The chemical reactions and pathways resulting in the breakdown of trimethylenediamine.	got7fsn_ti	trimethylenediamine degradation|trimethylenediamine breakdown|trimethylenediamine catabolism						yaf	2012-06-28T04:53:06Z						biological_process											owl:Class	
GO:0140285	biolink:NamedThing	endosome fission	The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.	got7fsn_ti							pg	2018-10-30T10:36:33Z						biological_process											owl:Class	
GO:0005301	biolink:NamedThing	obsolete valine/tyrosine/tryptophan permease activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	hydrogen/valine-tyrosine-tryptophan transporter|valine/tyrosine/tryptophan permease activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0005302|GO:0005304|GO:0015196|GO:0022857				True				molecular_function											owl:Class	
GO:0062198	biolink:NamedThing	obsolete rDNA replication pause site heterochromatin	OBSOLETE. A region of heterochromatin associated with sites in rDNA repeats where replication forks pause.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19178			This term was obsoleted because it does not represent a specific cellular component.		dph	2019-12-11T20:32:24Z		True				cellular_component											owl:Class	
GO:1905242	biolink:NamedThing	response to 3,3',5-triiodo-L-thyronine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.	got7fsn_ti	response to Liothyronine|response to Liothyronin|response to Liothyroninum						sl	2016-06-08T17:42:04Z						biological_process											owl:Class	
GO:0019319	biolink:NamedThing	hexose biosynthetic process	The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.	got7fsn_ti	hexose synthesis|hexose anabolism|hexose formation|hexose biosynthesis													biological_process											owl:Class	
GO:0006981	biolink:NamedThing	obsolete activation of SoxR protein	OBSOLETE. The conversion of the SoxR transcription factor to its active (oxidized) form.	got7fsn_ti					This term was made obsolete because it was too specific with respect to a single gene product.					True				biological_process											owl:Class	
GO:0051589	biolink:NamedThing	negative regulation of neurotransmitter transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	down regulation of neurotransmitter transport|down-regulation of neurotransmitter transport|inhibition of neurotransmitter transport|downregulation of neurotransmitter transport													biological_process											owl:Class	
GO:0071549	biolink:NamedThing	cellular response to dexamethasone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.	got7fsn_ti							mah	2010-01-13T01:24:49Z						biological_process											owl:Class	
GO:1904023	biolink:NamedThing	regulation of glucose catabolic process to lactate via pyruvate	Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.	got7fsn_ti	regulation of homolactic fermentation|regulation of homolactate fermentation|regulation of glucose fermentation to lactate via pyruvate|regulation of homofermentation|regulation of homofermentative lactate fermentation|regulation of homofermentative pathway						dph	2015-03-11T16:57:32Z						biological_process											owl:Class	
GO:1900380	biolink:NamedThing	negative regulation of asperthecin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process.	got7fsn_ti	negative regulation of asperthecin synthesis|down-regulation of asperthecin formation|negative regulation of asperthecin biosynthesis|down regulation of asperthecin formation|downregulation of asperthecin biosynthetic process|down regulation of asperthecin synthesis|downregulation of asperthecin synthesis|downregulation of asperthecin formation|down-regulation of asperthecin synthesis|down regulation of asperthecin biosynthesis|down regulation of asperthecin biosynthetic process|inhibition of asperthecin synthesis|negative regulation of asperthecin formation|inhibition of asperthecin biosynthesis|downregulation of asperthecin biosynthesis|inhibition of asperthecin formation|inhibition of asperthecin biosynthetic process|down-regulation of asperthecin biosynthesis|down-regulation of asperthecin biosynthetic process						di	2012-04-17T01:58:37Z						biological_process											owl:Class	
GO:0030637	biolink:NamedThing	obsolete acetate derivative catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of derivatives of acetic acid.	got7fsn_ti	acetate derivative catabolic process|acetate derivative catabolism|acetate derivative degradation|acetate derivative breakdown				This term was made obsolete because it is an unnecessary grouping term and has been replaced by terms to describe metabolism of specific compounds.					True				biological_process											owl:Class	
UBERON:0012175	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902066	biolink:NamedThing	regulation of cell wall pectin metabolic process	Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process.	got7fsn_ti	regulation of cell wall pectin metabolism|regulation of plant-type cell wall pectin metabolic process|regulation of cellulose and pectin-containing cell wall pectin metabolic process|regulation of pectin metabolism during cell wall biogenesis						tb	2013-04-17T20:05:56Z						biological_process											owl:Class	
GO:0038091	biolink:NamedThing	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation.	got7fsn_ti	VEGF-A-induced cell proliferation|positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signalling pathway|positive regulation of cell proliferation by VEGF/PDGFR signaling pathway						bf	2012-02-02T03:45:49Z						biological_process											owl:Class	
GO:0005949	biolink:NamedThing	obsolete aminoadipate-semialdehyde dehydrogenase complex	OBSOLETE. A heterodimeric enzyme composed of an alpha and beta subunit. Catalyzes the formation of L-2-aminoadipate from L-2-aminoadipate 6-semialdehyde.	got7fsn_ti	aminoadipate-semialdehyde dehydrogenase complex				This term was made obsolete because the catalytic activity resides in a single polypeptide that is not part of a complex with other gene products.					True				cellular_component											owl:Class	
GO:1901935	biolink:NamedThing	beta-caryophyllene metabolic process	The chemical reactions and pathways involving beta-caryophyllene.	got7fsn_ti	beta-caryophyllene metabolism						ms	2013-02-18T14:55:06Z						biological_process											owl:Class	
GO:0071326	biolink:NamedThing	cellular response to monosaccharide stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.	got7fsn_ti							mah	2009-12-10T05:27:18Z						biological_process											owl:Class	
GO:0072725	biolink:NamedThing	cellular response to 4-nitroquinoline N-oxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.	got7fsn_ti							mah	2012-05-31T11:00:42Z						biological_process											owl:Class	
GO:0035604	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.	got7fsn_ti	FGFR signaling pathway involved in positive regulation of cell proliferation in bone marrow|fibroblast growth factor receptor signalling pathway involved in positive regulation of cell proliferation in bone marrow|FGF receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow						bf	2010-11-15T11:10:14Z						biological_process											owl:Class	
GO:1901285	biolink:NamedThing	5,6,7,8-tetrahydromethanopterin biosynthetic process	The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin.	got7fsn_ti	5,6,7,8-tetrahydromethanopterin anabolism|5,6,7,8-tetrahydromethanopterin synthesis|5,6,7,8-tetrahydromethanopterin formation|5,6,7,8-tetrahydromethanopterin biosynthesis						yaf	2012-08-17T15:33:02Z						biological_process											owl:Class	
GO:2000246	biolink:NamedThing	positive regulation of FtsZ-dependent cytokinesis	Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis.	got7fsn_ti	positive regulation of prokaryote-type cytokinesis|positive regulation of prokaryotic fission						mah	2010-11-10T02:46:41Z						biological_process											owl:Class	
GO:0042497	biolink:NamedThing	triacyl lipopeptide binding	Binding to a lipopeptide containing a nonprotein moiety consisting of three acyl groups.	got7fsn_ti	triacylated lipopeptide binding|bacterial triacyl lipopeptide binding|bacterial triacyl lipoprotein binding				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.									molecular_function											owl:Class	
GO:0043377	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta T cell differentiation	Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.	got7fsn_ti	negative regulation of CD8-positive T-lymphocyte differentiation|downregulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha beta T lymphocyte differentiation|negative regulation of CD8-positive, alpha beta T-cell differentiation|down regulation of CD8-positive, alpha-beta T cell differentiation|down-regulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha-beta T cell development|inhibition of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha beta T-lymphocyte differentiation|negative regulation of CD8-positive T lymphocyte differentiation|negative regulation of CD8-positive T-cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0097337	biolink:NamedThing	response to ziprasidone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.	got7fsn_ti							pr	2012-06-12T11:05:31Z						biological_process											owl:Class	
UBERON:0002046	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097173	biolink:NamedThing	N-acetylmuramic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.	got7fsn_ti	N-acetylmuramate breakdown|N-acetylmuramic acid breakdown|N-acetylmuramic acid catabolism|N-acetylmuramic acid degradation|N-acetylmuramate catabolism|N-acetylmuramate degradation|N-acetylmuramate catabolic process						pr	2011-10-07T12:48:47Z						biological_process											owl:Class	
GO:1990376	biolink:NamedThing	obsolete negative regulation of G1/S transition of mitotic cell cycle by positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation that results in negative regulation of mitotic G1/S transition.	got7fsn_ti					This term was made obsolete because it would not be used for annotation.		al	2014-05-07T08:51:19Z		True				biological_process											owl:Class	
GO:1901984	biolink:NamedThing	negative regulation of protein acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation.	got7fsn_ti	down-regulation of protein amino acid acetylation|negative regulation of protein amino acid acetylation|down-regulation of protein acetylation|inhibition of protein amino acid acetylation|downregulation of protein acetylation|downregulation of protein amino acid acetylation|down regulation of protein acetylation|inhibition of protein acetylation|down regulation of protein amino acid acetylation						ss	2013-03-14T00:40:11Z						biological_process											owl:Class	
GO:0051185	biolink:NamedThing	obsolete coenzyme transmembrane transporter activity	OBSOLETE. Enables the transfer of a coenzyme from one side of a membrane to the other. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	got7fsn_ti	coenzyme transporter activity				1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a coenzyme.					True				molecular_function											owl:Class	
GO:0019299	biolink:NamedThing	rhamnose metabolic process	The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.	got7fsn_ti	rhamnose metabolism													biological_process											owl:Class	
GO:0007572	biolink:NamedThing	obsolete age dependent decreased translational activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	age dependent decreased translational activity				This term was made obsolete because it does not describe a biological process.	GO:0007571				True				biological_process											owl:Class	
GO:0015286	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905179	biolink:NamedThing	negative regulation of cardiac muscle tissue regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration.	got7fsn_ti	down-regulation of cardiac muscle tissue regeneration|downregulation of cardiac muscle tissue regeneration|down regulation of cardiac muscle tissue regeneration|inhibition of cardiac muscle tissue regeneration						rph	2016-05-05T11:30:57Z						biological_process											owl:Class	
GO:1904132	biolink:NamedThing	positive regulation of convergent extension involved in neural plate elongation	Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation.	got7fsn_ti	up-regulation of convergent extension involved in neural plate elongation|up regulation of convergent extension involved in neural plate elongation|activation of convergent extension involved in neural plate elongation|upregulation of convergent extension involved in neural plate elongation						dph	2015-04-10T21:13:33Z						biological_process											owl:Class	
GO:0075172	biolink:NamedThing	obsolete positive regulation of MAP kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont MAP kinase-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1901521	biolink:NamedThing	aspyridone B biosynthetic process	The chemical reactions and pathways resulting in the formation of aspyridone B.	got7fsn_ti	aspyridone B biosynthesis|aspyridone B formation|aspyridone B synthesis|aspyridone B anabolism						di	2012-10-18T18:31:52Z						biological_process											owl:Class	
GO:1902838	biolink:NamedThing	regulation of nuclear migration along microtubule	Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.	got7fsn_ti	regulation of microtubule cytoskeleton-dependent nucleus positioning|regulation of transport of nucleus, microtubule-mediated|regulation of nuclear migration, microtubule-mediated|regulation of microtubule-mediated nuclear migration|regulation of transport of nucleus by microtubules|regulation of nuclear movement, microtubule-mediated|regulation of microtubule-dependent nuclear positioning|regulation of nucleus migration|regulation of microtubule cytoskeleton-dependent nuclear positioning|regulation of microtubule-dependent nucleus positioning						vw	2014-04-01T13:50:23Z						biological_process											owl:Class	
GO:0075149	biolink:NamedThing	obsolete negative regulation of signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0098782	biolink:NamedThing	mechanosensitived potassium channel activity	Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress.	got7fsn_ti	mechanically-gated potassium channel activity													molecular_function											owl:Class	
GO:0010671	biolink:NamedThing	obsolete negative regulation of oxygen and reactive oxygen species metabolic process	OBSOLETE. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).	got7fsn_ti	negative regulation of oxygen and reactive oxygen species metabolic process				This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together.	GO:2000375|GO:2000378				True				biological_process											owl:Class	
GO:0150071	biolink:NamedThing	negative regulation of arginase activity	Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity.	got7fsn_ti							bc	2018-07-25T09:22:32Z						biological_process											owl:Class	
GO:1900514	biolink:NamedThing	positive regulation of starch utilization system complex assembly	Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly.	got7fsn_ti	up regulation of SUS complex assembly|upregulation of starch utilization system complex assembly|up regulation of assembly of starch utilization system complex|positive regulation of assembly of starch utilization system complex|up-regulation of starch utilization system complex assembly|activation of assembly of starch utilization system complex|upregulation of assembly of starch utilization system complex|positive regulation of SUS complex assembly|up-regulation of SUS complex assembly|upregulation of SUS complex assembly|up-regulation of assembly of starch utilization system complex|up regulation of starch utilization system complex assembly|activation of SUS complex assembly|activation of starch utilization system complex assembly						tt	2012-05-02T04:07:04Z						biological_process											owl:Class	
GO:0045891	biolink:NamedThing	obsolete negative regulation of transcription of homeotic gene (trithorax group)	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the trithorax group.	got7fsn_ti	negative regulation of transcription of homeotic gene (trithorax group)				This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0000122				True				biological_process											owl:Class	
GO:0015356	biolink:NamedThing	obsolete monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0050833|GO:0015129|GO:0015130|GO:0015562				True				molecular_function											owl:Class	
GO:2000446	biolink:NamedThing	regulation of macrophage migration inhibitory factor signaling pathway	Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.	got7fsn_ti	regulation of MIF signaling pathway|regulation of macrophage migration inhibitory factor signalling pathway						bf	2011-03-04T10:37:39Z						biological_process											owl:Class	
GO:0002835	biolink:NamedThing	negative regulation of response to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.	got7fsn_ti	negative regulation of response to tumour cell|down-regulation of response to tumor cell|downregulation of response to tumor cell|down regulation of response to tumor cell|inhibition of response to tumor cell													biological_process											owl:Class	
GO:1902030	biolink:NamedThing	negative regulation of histone H3-K18 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K18 acetylation.	got7fsn_ti	downregulation of histone H3 acetylation at K18|inhibition of histone H3K18 acetylation|down-regulation of histone H3K18 acetylation|downregulation of histone H3K18 acetylation|down-regulation of histone H3 acetylation at K18|inhibition of histone H3-K18 acetylation|downregulation of histone H3-K18 acetylation|negative regulation of histone H3K18 acetylation|down regulation of histone H3 acetylation at K18|inhibition of histone H3 acetylation at K18|down regulation of histone H3-K18 acetylation|negative regulation of histone H3 acetylation at K18|down-regulation of histone H3-K18 acetylation|down regulation of histone H3K18 acetylation						jl	2013-03-28T20:19:39Z						biological_process											owl:Class	
GO:1904699	biolink:NamedThing	positive regulation of acinar cell proliferation	Any process that activates or increases the frequency, rate or extent of acinar cell proliferation.	got7fsn_ti	activation of acinous cell proliferation|up-regulation of acinic cell proliferation|up-regulation of acinous cell proliferation|up-regulation of acinar cell proliferation|up regulation of acinous cell proliferation|upregulation of acinous cell proliferation|upregulation of acinar cell proliferation|up regulation of acinic cell proliferation|positive regulation of acinic cell proliferation|upregulation of acinic cell proliferation|positive regulation of acinous cell proliferation|activation of acinic cell proliferation|activation of acinar cell proliferation|up regulation of acinar cell proliferation						sl	2015-09-30T15:20:03Z						biological_process											owl:Class	
GO:0042205	biolink:NamedThing	chlorinated hydrocarbon catabolic process	The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.	got7fsn_ti	chlorinated hydrocarbon catabolism|chlorinated hydrocarbon degradation|chlorinated hydrocarbon breakdown													biological_process											owl:Class	
GO:1902487	biolink:NamedThing	protein localization to non-growing cell tip	A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip.	got7fsn_ti	protein localization in non-growing cell tip|protein localisation to non-growing cell tip|protein localisation in non-growing cell tip						mah	2013-11-12T16:38:22Z						biological_process											owl:Class	
GO:0019359	biolink:NamedThing	nicotinamide nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.	got7fsn_ti	nicotinamide nucleotide synthesis|nicotinamide nucleotide formation|nicotinamide nucleotide biosynthesis|nicotinamide nucleotide anabolism													biological_process											owl:Class	
OIO:hasAlternativeId	biolink:NamedThing	has_alternative_id		got7fsn_ti																									owl:AnnotationProperty	
GO:0052408	biolink:NamedThing	obsolete metabolism by host of symbiont cell wall cellulose	OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1905643	biolink:NamedThing	positive regulation of DNA methylation	Any process that activates or increases the frequency, rate or extent of DNA methylation.	got7fsn_ti	upregulation of DNA methylation|up regulation of DNA methylation|activation of DNA methylation|up-regulation of DNA methylation						bc	2016-11-04T16:43:22Z						biological_process											owl:Class	
GO:2000374	biolink:NamedThing	regulation of oxygen metabolic process	Any process that modulates the frequency, rate or extent of oxygen metabolic process.	got7fsn_ti	regulation of oxygen metabolism|regulation of diatomic oxygen metabolic process						mah	2011-02-11T02:03:32Z						biological_process											owl:Class	
GO:0044435	biolink:NamedThing	obsolete plastid part	OBSOLETE. Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009536				True				cellular_component											owl:Class	
GO:1904187	biolink:NamedThing	regulation of transformation of host cell by virus	Any process that modulates the frequency, rate or extent of transformation of host cell by virus.	got7fsn_ti	regulation of viral transformation of host cell|regulation of viral transformation						pga	2015-05-05T15:29:58Z						biological_process											owl:Class	
GO:0035956	biolink:NamedThing	obsolete regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of the breakdown of starch, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of starch catabolism by regulation of transcription from Pol II promoter|regulation of starch catabolic process by regulation of transcription from Pol II promoter|regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter|regulation of starch degradation by regulation of transcription from Pol II promoter|regulation of starch degradation by regulation of transcription from RNA polymerase II promoter|regulation of starch breakdown by regulation of transcription from Pol II promoter|regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0085022	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:32:02Z		True				biological_process											owl:Class	
GO:1903184	biolink:NamedThing	L-dopa metabolic process	The chemical reactions and pathways involving L-dopa.	got7fsn_ti	L-dopa metabolism						bf	2014-07-14T15:06:00Z						biological_process											owl:Class	
GO:0019002	biolink:NamedThing	GMP binding	Binding to GMP, guanosine monophosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0006552	biolink:NamedThing	leucine catabolic process	The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid.	got7fsn_ti	leucine catabolism|leucine degradation|leucine breakdown											MetaCyc:LEU-DEG2-PWY		biological_process											owl:Class	
GO:0019443	biolink:NamedThing	obsolete tryptophan catabolic process, using tryptophanase	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tryptophan, catalyzed by the enzyme tryptophanase (EC:4.1.99.1).	got7fsn_ti	tryptophan catabolic process, using tryptophanase|tryptophan breakdown, using tryptophanase|tryptophan degradation, using tryptophanase				This term was made obsolete because it refers to a one-step pathway.	GO:0009034|GO:0006569				True				biological_process											owl:Class	
GO:1905023	biolink:NamedThing	positive regulation of threonine-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity.	got7fsn_ti	up-regulation of threonyl-transfer RNA synthetase activity|upregulation of TRS|up regulation of TRS|up regulation of threonine-tRNA ligase activity|activation of threonyl ribonucleic synthetase activity|upregulation of threonyl ribonucleic synthetase activity|activation of threonyl-transfer ribonucleate synthetase activity|upregulation of L-threonine:tRNAThr ligase (AMP-forming)|up regulation of threonyl-transfer ribonucleate synthetase activity|up-regulation of threonine-tRNA ligase activity|positive regulation of threonyl ribonucleic synthetase activity|activation of TRS|activation of threonine-transfer ribonucleate synthetase activity|upregulation of threonyl-transfer ribonucleic acid synthetase activity|activation of threonyl-tRNA synthetase activity|positive regulation of L-threonine:tRNAThr ligase (AMP-forming)|positive regulation of threonyl-transfer RNA synthetase activity|activation of threonyl-transfer RNA synthetase activity|upregulation of threonine-transfer ribonucleate synthetase activity|up-regulation of threonyl-transfer ribonucleic acid synthetase activity|up regulation of threonyl-tRNA synthetase activity|upregulation of threonyl-transfer RNA synthetase activity|positive regulation of TRS|positive regulation of threonyl-tRNA synthetase activity|positive regulation of threonine-transfer ribonucleate synthetase activity|activation of threonine-tRNA ligase activity|up regulation of L-threonine:tRNAThr ligase (AMP-forming)|positive regulation of threonine translase activity|positive regulation of threonyl-transfer ribonucleic acid synthetase activity|up-regulation of threonyl-transfer ribonucleate synthetase activity|upregulation of threonine-tRNA ligase activity|upregulation of threonyl-transfer ribonucleate synthetase activity|up-regulation of threonine translase activity|activation of threonine translase activity|up regulation of threonine translase activity|up-regulation of threonyl-tRNA synthetase activity|up regulation of threonyl-transfer ribonucleic acid synthetase activity|up-regulation of TRS|up-regulation of threonyl ribonucleic synthetase activity|up-regulation of threonine-transfer ribonucleate synthetase activity|upregulation of threonyl-tRNA synthetase activity|up regulation of threonyl-transfer RNA synthetase activity|positive regulation of threonyl-transfer ribonucleate synthetase activity|up-regulation of L-threonine:tRNAThr ligase (AMP-forming)|activation of L-threonine:tRNAThr ligase (AMP-forming)|activation of threonyl-transfer ribonucleic acid synthetase activity|upregulation of threonine translase activity|up regulation of threonyl ribonucleic synthetase activity|up regulation of threonine-transfer ribonucleate synthetase activity						sl	2016-03-03T19:12:41Z						biological_process											owl:Class	
GO:1903528	biolink:NamedThing	regulation of dCDP biosynthetic process	Any process that modulates the frequency, rate or extent of dCDP biosynthetic process.	got7fsn_ti	regulation of dCDP biosynthesis|regulation of dCDP anabolism|regulation of dCDP synthesis|regulation of dCDP formation						al	2014-10-07T15:01:18Z						biological_process											owl:Class	
GO:1901752	biolink:NamedThing	leukotriene A4 catabolic process	The chemical reactions and pathways resulting in the breakdown of leukotriene A4.	got7fsn_ti	leukotriene A4 degradation|leukotriene A4 breakdown|leukotriene A4 catabolism						yaf	2013-01-14T11:05:04Z						biological_process											owl:Class	
GO:1901129	biolink:NamedThing	gentamycin catabolic process	The chemical reactions and pathways resulting in the breakdown of gentamycin.	got7fsn_ti	gentamycin degradation|gentamycin breakdown|gentamycin catabolism						yaf	2012-07-11T03:26:51Z						biological_process											owl:Class	
GO:0009261	biolink:NamedThing	ribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	ribonucleotide breakdown|ribonucleotide degradation|ribonucleotide catabolism													biological_process											owl:Class	
GO:0006217	biolink:NamedThing	deoxycytidine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.	got7fsn_ti	deoxycytidine degradation|deoxycytidine breakdown|deoxycytidine catabolism													biological_process											owl:Class	
GO:0098729	biolink:NamedThing	germline stem cell symmetric division	Division of a germline stem cell to produce two germline stem cells of the same type as the parent.	got7fsn_ti														biological_process											owl:Class	
GO:0030438	biolink:NamedThing	obsolete MAPKKK cascade during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	MAPKKK cascade during sporulation (sensu Fungi)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:1905041	biolink:NamedThing	regulation of epithelium regeneration	Any process that modulates the frequency, rate or extent of epithelium regeneration.	got7fsn_ti	regulation of regeneration of epithelium						rph	2016-03-11T10:58:53Z						biological_process											owl:Class	
GO:0043289	biolink:NamedThing	apocarotenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.	got7fsn_ti	apo carotenoid biosynthetic process|apocarotenoid biosynthesis|apocarotenoid anabolism|apocarotenoid synthesis|apocarotenoid formation													biological_process											owl:Class	
GO:0075173	biolink:NamedThing	obsolete negative regulation of MAP kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont MAP kinase-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0019847	biolink:NamedThing	obsolete neurotoxin activity	OBSOLETE. Acts to inhibit neural function in another living organism.	got7fsn_ti	neurotoxin activity				This term was made obsolete because it represents a class of gene products.	GO:0090729				True				molecular_function											owl:Class	
GO:1900642	biolink:NamedThing	positive regulation of austinol biosynthetic process	Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process.	got7fsn_ti	activation of austinol anabolism|positive regulation of austinol anabolism|up regulation of austinol synthesis|positive regulation of austinol synthesis|upregulation of austinol biosynthesis|up-regulation of austinol anabolism|up regulation of austinol biosynthetic process|upregulation of austinol biosynthetic process|activation of austinol formation|upregulation of austinol formation|up regulation of austinol anabolism|activation of austinol biosynthetic process|activation of austinol biosynthesis|activation of austinol synthesis|up regulation of austinol formation|positive regulation of austinol formation|upregulation of austinol synthesis|up-regulation of austinol biosynthesis|positive regulation of austinol biosynthesis|up-regulation of austinol biosynthetic process|upregulation of austinol anabolism|up regulation of austinol biosynthesis|up-regulation of austinol synthesis|up-regulation of austinol formation						di	2012-05-22T03:58:07Z						biological_process											owl:Class	
GO:1900731	biolink:NamedThing	positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.	got7fsn_ti	up regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|activation of opioid receptor-mediated adenylate cyclase inhibition|upregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|activation of adenylate cyclase-inhibiting opioid receptor signaling pathway						bf	2012-05-25T03:21:19Z						biological_process											owl:Class	
GO:0043945	biolink:NamedThing	positive regulation of asexual sporulation resulting in formation of a cellular spore	Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.	got7fsn_ti														biological_process											owl:Class	
GO:0016665	biolink:NamedThing	obsolete oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, oxygen, NAD or NADP.	got7fsn_ti	oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016661				True				molecular_function											owl:Class	
GO:0071810	biolink:NamedThing	regulation of fever generation by regulation of prostaglandin secretion	Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	got7fsn_ti							mah	2010-09-03T05:09:27Z						biological_process											owl:Class	
GO:0042142	biolink:NamedThing	obsolete heavy metal chelation	OBSOLETE. The strong but reversible binding of a heavy metal ion by a larger molecule such as protein.	got7fsn_ti	heavy metal chelation			GO:0046911	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:0033662	biolink:NamedThing	obsolete modulation by symbiont of host defense-related protein level	OBSOLETE. The alternation by a symbiont of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it is a readout, and annotations should be made to more informative terms.					True				biological_process											owl:Class	
GO:0006299	biolink:NamedThing	obsolete short patch mismatch repair system	OBSOLETE. The repair of mismatched DNA where the gap to be repaired is only one nucleotide. DNA polymerase is the preferred polymerase in short patch repair, performing gap filling DNA synthesis and removal of the 5'-deoxyribose phosphate of the abasic site.	got7fsn_ti	short patch mismatch repair system				This term was made obsolete because 'short patch' is a relative statement, often used ambiguously, and does not necessarily represent a process; the processes it can stand for are base excision repair, nucleotide excision repair, transcription-coupled nucleotide excision repair, and mismatch repair.	GO:0006284|GO:0006289				True				biological_process											owl:Class	
GO:1902310	biolink:NamedThing	positive regulation of peptidyl-serine dephosphorylation	Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation.	got7fsn_ti	up-regulation of peptidyl-serine dephosphorylation|activation of peptidyl-serine dephosphorylation|up regulation of peptidyl-serine dephosphorylation|upregulation of peptidyl-serine dephosphorylation						rl	2013-07-19T10:35:15Z						biological_process											owl:Class	
GO:0034765	biolink:NamedThing	regulation of ion transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.	got7fsn_ti	regulation of ion membrane transport|regulation of transmembrane ion transport													biological_process											owl:Class	
GO:0045429	biolink:NamedThing	positive regulation of nitric oxide biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.	got7fsn_ti	stimulation of nitric oxide biosynthetic process|up-regulation of nitric oxide biosynthetic process|up regulation of nitric oxide biosynthetic process|positive regulation of nitric oxide biosynthesis|positive regulation of nitric oxide synthesis|positive regulation of nitric oxide anabolism|activation of nitric oxide biosynthetic process|upregulation of nitric oxide biosynthetic process|positive regulation of nitric oxide formation													biological_process											owl:Class	
GO:1904715	biolink:NamedThing	negative regulation of chaperone-mediated autophagy	Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy.	got7fsn_ti	inhibition of chaperone-mediated autophagy|down-regulation of chaperone-mediated autophagy|downregulation of CMA|down regulation of chaperone-mediated autophagy|negative regulation of CMA|downregulation of chaperone-mediated autophagy|down regulation of CMA|inhibition of CMA|down-regulation of CMA						pad	2015-10-06T08:49:09Z						biological_process											owl:Class	
GO:0030528	biolink:NamedThing	obsolete transcription regulator activity	OBSOLETE. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.	got7fsn_ti	transcription regulator activity|transcriptional regulator activity			GO:0140110	This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.					True				molecular_function											owl:Class	
GO:0052176	biolink:NamedThing	obsolete metabolism by symbiont of host glucan	OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0035121	biolink:NamedThing	obsolete tail morphogenesis	OBSOLETE. The process in which the anatomical structures of the tail are generated and organized. The tail is the hindmost part of some animals.	got7fsn_ti	tail morphogenesis				This term was made obsolete because 'tail' has different meanings in different organisms, and is therefore not a useful grouping term.	GO:0048809|GO:0003002|GO:0036342				True				biological_process											owl:Class	
GO:1902359	biolink:NamedThing	Notch signaling pathway involved in somitogenesis	Any Notch signaling pathway that is involved in somitogenesis.	got7fsn_ti	Notch receptor signaling pathway involved in formation of mesodermal clusters|N signalling pathway involved in somitogenesis|Notch signalling pathway involved in somitogenesis|Notch signaling pathway involved in formation of mesodermal clusters|Notch-receptor signalling pathway involved in formation of mesodermal clusters|Notch receptor signalling pathway involved in somitogenesis|N signaling pathway involved in formation of mesodermal clusters|Notch signalling pathway involved in formation of mesodermal clusters|Notch receptor signalling pathway involved in formation of mesodermal clusters|Notch receptor signaling pathway involved in somitogenesis|Notch-receptor signaling pathway involved in somitogenesis|Notch-receptor signalling pathway involved in somitogenesis|N signalling pathway involved in formation of mesodermal clusters|N signaling pathway involved in somitogenesis|Notch-receptor signaling pathway involved in formation of mesodermal clusters						dph	2013-08-14T17:31:43Z						biological_process											owl:Class	
GO:2000312	biolink:NamedThing	regulation of kainate selective glutamate receptor activity	Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity.	got7fsn_ti							bf	2011-01-18T10:14:16Z						biological_process											owl:Class	
GO:1903967	biolink:NamedThing	response to micafungin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.	got7fsn_ti							al	2015-02-27T09:57:38Z						biological_process											owl:Class	
GO:0032773	biolink:NamedThing	positive regulation of tyrosinase activity	Any process that activates or increases the activity of a tyrosinase enzyme monophenol oxygenase.	got7fsn_ti	up regulation of monophenol oxygenase activity|positive regulation of monophenol oxygenase activity|stimulation of monophenol oxygenase activity|positive regulation of monophenol monooxygenase activity|upregulation of monophenol oxygenase activity|activation of monophenol oxygenase activity|up-regulation of monophenol oxygenase activity	https://github.com/geneontology/go-ontology/issues/21024												biological_process											owl:Class	
GO:1904577	biolink:NamedThing	cellular response to tunicamycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus.	got7fsn_ti							sl	2015-08-19T18:01:58Z						biological_process											owl:Class	
GO:1905327	biolink:NamedThing	tracheoesophageal septum formation	The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts.	got7fsn_ti	esophagotracheal septum formation|tracheoesophageal ridges formation						tb	2016-07-21T18:18:57Z						biological_process											owl:Class	
GO:0090289	biolink:NamedThing	regulation of osteoclast proliferation	Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.	got7fsn_ti							tb	2010-02-18T03:11:03Z						biological_process											owl:Class	
GO:0052455	biolink:NamedThing	obsolete modulation by organism of jasmonic acid levels in symbiont	OBSOLETE. The alteration by an organism of the levels of jasmonic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of jasmonic acid levels in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0033584	biolink:NamedThing	tyrosine biosynthetic process from chorismate via L-arogenate	The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate.	got7fsn_ti	tyrosine anabolism from chorismate via L-arogenate|tyrosine formation from chorismate via L-arogenate|tyrosine synthesis from chorismate via L-arogenate											MetaCyc:PWY-3461		biological_process											owl:Class	
GO:0034339	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to modulate the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor				This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand.	GO:0004879|GO:0030522|GO:0030374|GO:0006357				True				biological_process											owl:Class	
CHEBI:32678	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035422	biolink:NamedThing	obsolete activation of MAPKKK activity involved in innate immune response	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18000			This term was obsoleted because it should be represented as a GO-CAM model.		bf	2010-03-29T01:27:38Z		True				biological_process											owl:Class	
GO:1904197	biolink:NamedThing	positive regulation of granulosa cell proliferation	Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation.	got7fsn_ti	up regulation of granulosa cell proliferation|up-regulation of granulosa cell proliferation|upregulation of granulosa cell proliferation|activation of granulosa cell proliferation						sl	2015-05-07T17:02:40Z						biological_process											owl:Class	
GO:2000107	biolink:NamedThing	negative regulation of leukocyte apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.	got7fsn_ti	negative regulation of leukocyte apoptosis						mah	2010-09-15T01:42:09Z						biological_process											owl:Class	
GO:1901760	biolink:NamedThing	beta-L-Ara4N-lipid A biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.	got7fsn_ti	beta-L-Ara4N-lipid A biosynthesis|4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthetic process|beta-L-Ara4N-lipid A anabolism|beta-L-Ara4N-lipid A formation|beta-L-Ara4N-lipid A synthesis|4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis						pr	2013-01-14T12:53:01Z						biological_process											owl:Class	
GO:0071237	biolink:NamedThing	cellular response to bacteriocin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.	got7fsn_ti							mah	2009-12-03T02:25:43Z						biological_process											owl:Class	
GO:0006851	biolink:NamedThing	mitochondrial calcium ion transmembrane transport	The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti	mitochondrial calcium transport													biological_process											owl:Class	
GO:1902654	biolink:NamedThing	aromatic primary alcohol metabolic process	The chemical reactions and pathways involving aromatic primary alcohol.	got7fsn_ti	aromatic primary alcohol metabolism						tt	2014-01-22T10:47:21Z						biological_process											owl:Class	
GO:1902246	biolink:NamedThing	cis-abienol biosynthetic process	The chemical reactions and pathways resulting in the formation of cis-abienol.	got7fsn_ti	cis-abienol synthesis|cis-abienol formation|cis-abienol anabolism|cis-abienol biosynthesis						ms	2013-06-20T09:10:02Z						biological_process											owl:Class	
GO:0043947	biolink:NamedThing	obsolete positive regulation by host of symbiont catalytic activity	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by host of symbiont enzyme activity|activation by host of symbiont enzyme activity|up-regulation by host of symbiont enzyme activity|activation of symbiont enzyme activity|up regulation by host of symbiont enzyme activity|upregulation by host of symbiont enzyme activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0034301	biolink:NamedThing	endospore formation	The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions.	got7fsn_ti														biological_process											owl:Class	
GO:0046796	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904475	biolink:NamedThing	regulation of small GTPase binding	Any process that modulates the frequency, rate or extent of small GTPase binding.	got7fsn_ti	regulation of Ras GTPase binding	https://github.com/geneontology/go-ontology/issues/18750					sl	2015-07-10T22:47:31Z						biological_process											owl:Class	
GO:0075063	biolink:NamedThing	obsolete positive regulation of invasive hypha growth	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont invasive hypha formation within host|positive regulation of symbiont invasive hypha formation in host	https://github.com/geneontology/go-ontology/issues/19013			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1900389	biolink:NamedThing	obsolete regulation of glucose import by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of glucose import.	got7fsn_ti	regulation of glucose uptake by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-18T03:52:43Z		True				biological_process											owl:Class	
CHEBI:58117	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034618	biolink:NamedThing	arginine binding	Binding to 2-amino-5-(carbamimidamido)pentanoic acid.	got7fsn_ti	aminopentanoic acid binding|Arg binding													molecular_function											owl:Class	
GO:0052458	biolink:NamedThing	obsolete modulation by organism of symbiont non-apoptotic programmed cell death	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont non-apoptotic programmed cell death				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0140532	biolink:NamedThing	negative regulation of osmosensory signaling MAPK cascade	Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling MAPK cascade.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20162					pg	2020-10-20T15:39:24Z						biological_process											owl:Class	
GO:1901914	biolink:NamedThing	negative regulation of capsule organization	Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization.	got7fsn_ti	down-regulation of capsule organization|down-regulation of capsule organisation|inhibition of capsule organisation|negative regulation of capsule organization and biogenesis|down-regulation of capsule organization and biogenesis|inhibition of capsule organization and biogenesis|inhibition of capsule organization|downregulation of capsule organization|downregulation of capsule organisation|negative regulation of capsule organisation|down regulation of capsule organisation|down regulation of capsule organization and biogenesis|downregulation of capsule organization and biogenesis|down regulation of capsule organization						di	2013-02-14T06:19:07Z						biological_process											owl:Class	
GO:0002855	biolink:NamedThing	regulation of natural killer cell mediated immune response to tumor cell	Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.	got7fsn_ti														biological_process											owl:Class	
GO:0098975	biolink:NamedThing	postsynapse of neuromuscular junction	The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma.	got7fsn_ti														cellular_component											owl:Class	
GO:1900962	biolink:NamedThing	regulation of methanophenazine biosynthetic process	Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process.	got7fsn_ti	regulation of methanophenazine biosynthesis|regulation of methanophenazine synthesis|regulation of methanophenazine formation|regulation of methanophenazine anabolism						tt	2012-06-14T03:53:15Z						biological_process											owl:Class	
GO:1902455	biolink:NamedThing	negative regulation of stem cell population maintenance	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.	got7fsn_ti	down-regulation of maintenance of pluripotency|down-regulation of stem cell maintenance|downregulation of maintenance of pluripotency|downregulation of stem cell maintenance|inhibition of stem cell maintenance|inhibition of maintenance of pluripotency|down regulation of stem cell maintenance|negative regulation of maintenance of pluripotency|down regulation of maintenance of pluripotency						cjm	2013-10-16T22:19:17Z						biological_process											owl:Class	
GO:1900520	biolink:NamedThing	positive regulation of response to pullulan	Any process that activates or increases the frequency, rate or extent of response to pullulan.	got7fsn_ti	upregulation of response to pullulan|up-regulation of response to pullulan|up regulation of response to pullulan|activation of response to pullulan						tt	2012-05-02T04:12:19Z						biological_process											owl:Class	
GO:0019832	biolink:NamedThing	obsolete mercuric sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	mercuric sensitivity/resistance			GO:0046689	This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0045936	biolink:NamedThing	negative regulation of phosphate metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.	got7fsn_ti	inhibition of phosphate metabolic process|down-regulation of phosphate metabolic process|down regulation of phosphate metabolic process|negative regulation of phosphate metabolism|downregulation of phosphate metabolic process													biological_process											owl:Class	
GO:2000442	biolink:NamedThing	positive regulation of toll-like receptor 15 signaling pathway	Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway.	got7fsn_ti	positive regulation of TLR15 signaling pathway|positive regulation of toll-like receptor 15 signalling pathway						bf	2011-03-04T10:29:36Z						biological_process											owl:Class	
GO:0007068	biolink:NamedThing	obsolete negative regulation of transcription during mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.	got7fsn_ti	negative regulation of transcription, mitotic|mitotic repression of transcription|downregulation of transcription during mitosis|down-regulation of transcription during mitosis|down regulation of transcription during mitosis|inhibition of transcription during mitosis	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0000122				True				biological_process											owl:Class	
GO:0014741	biolink:NamedThing	negative regulation of muscle hypertrophy	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.	got7fsn_ti														biological_process											owl:Class	
GO:0003736	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002134	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097288	biolink:NamedThing	7-cyano-7-deazaguanine biosynthetic process	The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.	got7fsn_ti	7-cyano-7-deazaguanine synthesis|7-cyano-7-deazaguanine biosynthesis|7-cyano-7-deazaguanine formation|7-cyano-7-deazaguanine anabolism						pr	2012-04-25T10:53:47Z						biological_process											owl:Class	
GO:0043465	biolink:NamedThing	regulation of fermentation	Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP).	got7fsn_ti														biological_process											owl:Class	
GO:0005735	biolink:NamedThing	obsolete box H + ACA snoRNP protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	box H + ACA snoRNP protein				This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
GO:1902351	biolink:NamedThing	response to imidacloprid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus.	got7fsn_ti							kmv	2013-08-13T19:33:15Z						biological_process											owl:Class	
GO:2000088	biolink:NamedThing	negative regulation of mesonephric glomerulus development	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development.	got7fsn_ti							dph	2010-09-03T06:09:22Z						biological_process											owl:Class	
GO:1905923	biolink:NamedThing	positive regulation of acetylcholine biosynthetic process	Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process.	got7fsn_ti	upregulation of acetylcholine anabolism|up regulation of acetylcholine biosynthetic process|up-regulation of acetylcholine formation|upregulation of acetylcholine formation|positive regulation of acetylcholine anabolism|up-regulation of acetylcholine biosynthesis|upregulation of acetylcholine biosynthetic process|positive regulation of acetylcholine biosynthesis|upregulation of acetylcholine synthesis|activation of acetylcholine biosynthetic process|up regulation of acetylcholine synthesis|up-regulation of acetylcholine anabolism|up regulation of acetylcholine anabolism|positive regulation of acetylcholine formation|activation of acetylcholine anabolism|activation of acetylcholine synthesis|up-regulation of acetylcholine biosynthetic process|upregulation of acetylcholine biosynthesis|positive regulation of acetylcholine synthesis|up-regulation of acetylcholine synthesis|up regulation of acetylcholine formation|activation of acetylcholine formation|activation of acetylcholine biosynthesis|up regulation of acetylcholine biosynthesis						bc	2017-02-08T13:08:48Z						biological_process											owl:Class	
GO:0031185	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905567	biolink:NamedThing	obsolete positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	OBSOLETE. Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport.	got7fsn_ti	up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|activation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis of LDL|activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport				This term was obsoleted at the TermGenie Gatekeeper stage.		nc	2016-10-18T10:58:54Z		True				biological_process											owl:Class	
GO:1901953	biolink:NamedThing	positive regulation of anterograde dense core granule transport	Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport.	got7fsn_ti	up regulation of anterograde dense core granule transport|upregulation of anterograde dense core granule transport|up-regulation of anterograde dense core granule transport|activation of anterograde dense core granule transport						pr	2013-02-19T13:36:35Z						biological_process											owl:Class	
GO:1902282	biolink:NamedThing	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential						rl	2013-07-05T20:12:22Z						molecular_function											owl:Class	
CHEBI:35404	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900290	biolink:NamedThing	positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.	got7fsn_ti	up regulation of coenzyme F420-dependent nitroreductase activity|up-regulation of coenzyme F420-dependent nitroimidazole breakdown|up regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|up-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|up-regulation of coenzyme F420-dependent nitroimidazole catabolism|upregulation of coenzyme F420-dependent nitroimidazole reduction|upregulation of coenzyme F420-dependent nitroimidazole breakdown|up regulation of coenzyme F420-dependent nitroimidazole catabolism|activation of coenzyme F420-dependent nitroimidazole reduction|positive regulation of coenzyme F420-dependent nitroimidazole reduction|up-regulation of coenzyme F420-dependent nitroimidazole reduction|activation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|positive regulation of coenzyme F420-dependent nitroimidazole catabolism|positive regulation of coenzyme F420-dependent nitroreductase activity|activation of coenzyme F420-dependent nitroimidazole breakdown|activation of coenzyme F420-dependent nitroimidazole catabolism|upregulation of coenzyme F420-dependent nitroimidazole catabolism|up regulation of coenzyme F420-dependent nitroimidazole breakdown|up-regulation of coenzyme F420-dependent nitroreductase activity|upregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|upregulation of coenzyme F420-dependent nitroreductase activity|up regulation of coenzyme F420-dependent nitroimidazole reduction|activation of coenzyme F420-dependent nitroreductase activity|positive regulation of coenzyme F420-dependent nitroimidazole breakdown						tt	2012-04-05T06:02:59Z						biological_process											owl:Class	
GO:0045669	biolink:NamedThing	positive regulation of osteoblast differentiation	Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.	got7fsn_ti	upregulation of osteoblast differentiation|up regulation of osteoblast differentiation|stimulation of osteoblast differentiation|activation of osteoblast differentiation|up-regulation of osteoblast differentiation													biological_process											owl:Class	
CHEBI:27705	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008225	biolink:NamedThing	obsolete Gram-negative antibacterial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, Gram-negative bacterial cells.	got7fsn_ti	Gram-negative antibacterial peptide activity				This term was made obsolete because it describes involvement in a process and not a function.	GO:0050829				True				molecular_function											owl:Class	
GO:0120047	biolink:NamedThing	positive regulation of protein localization to medial cortical node	Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node.	got7fsn_ti							krc	2017-06-02T17:30:38Z						biological_process											owl:Class	
GO:0002672	biolink:NamedThing	positive regulation of B cell anergy	Any process that activates or increases the frequency, rate, or extent of B cell anergy.	got7fsn_ti	positive regulation of B-lymphocyte anergy|up-regulation of B cell anergy|positive regulation of B lymphocyte anergy|activation of B cell anergy|up regulation of B cell anergy|stimulation of B cell anergy|upregulation of B cell anergy|positive regulation of B-cell anergy													biological_process											owl:Class	
GO:0090242	biolink:NamedThing	retinoic acid receptor signaling pathway involved in somitogenesis	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis.	got7fsn_ti	retinoic acid receptor signalling pathway involved in somitogenesis						tb	2010-01-22T10:42:54Z						biological_process											owl:Class	
GO:0099074	biolink:NamedThing	mitochondrion to lysosome transport	Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:0140244	biolink:NamedThing	regulation of translation at presynapse	Any process that regulates translation occurring at the presynapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/210			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:38:33Z						biological_process											owl:Class	
GO:0052467	biolink:NamedThing	obsolete modulation by organism of symbiont salicylic acid-mediated defense response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont SA-mediated defense response|modulation by organism of symbiont salicylic acid-mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1904933	biolink:NamedThing	regulation of cell proliferation in midbrain	Any process that modulates the frequency, rate or extent of cell proliferation in midbrain.	got7fsn_ti	regulation of mesencepahalic cell proliferation|regulation of cell proliferation in mesencephalon						bf	2016-02-01T13:16:11Z						biological_process											owl:Class	
GO:1902253	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.	got7fsn_ti	regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|regulation of signal transduction by p53 class mediator resulting in induction of apoptosis						rl	2013-06-20T19:41:38Z						biological_process											owl:Class	
GO:0045882	biolink:NamedThing	negative regulation of sulfur utilization	Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization.	got7fsn_ti	down regulation of sulfur utilization|inhibition of sulfur utilization|down-regulation of sulfur utilization|downregulation of sulfur utilization|negative regulation of sulphur utilization													biological_process											owl:Class	
GO:0035563	biolink:NamedThing	positive regulation of chromatin binding	Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	got7fsn_ti							bf	2010-05-19T10:29:41Z						biological_process											owl:Class	
CHEBI:7896	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0017093	biolink:NamedThing	obsolete sterol regulatory element-binding protein protease activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds within a sterol regulatory element binding protein (SREBP). SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.	got7fsn_ti	sterol regulatory element-binding protein protease activity|SREBP protease activity			GO:0008233	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0140639	biolink:NamedThing	positive regulation of pyroptosis	Any process that increases the frequency, rate or extent of pyroptosis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21399					pg	2021-05-11T05:19:17Z						biological_process											owl:Class	
GO:0097330	biolink:NamedThing	response to 5-fluoro-2'-deoxyuridine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.	got7fsn_ti							pr	2012-06-12T10:53:35Z						biological_process											owl:Class	
GO:0140316	biolink:NamedThing	obsolete vesicular transport adaptor activity	OBSOLETE. Binding directly to sorting signals in the cytosolic tails of transmembrane cargos (or transmembrane cargo receptors serving as recognition interfaces for lumenal cargos), to concentrate them into vesicles or tubules for transport via intracellular vesicular transport or the secretory pathway.	got7fsn_ti					Thi sterm was obsoleted because it represented an unnecessary grouping class.		pg	2019-03-28T12:03:57Z		True				molecular_function											owl:Class	
GO:1902995	biolink:NamedThing	positive regulation of phospholipid efflux	Any process that activates or increases the frequency, rate or extent of phospholipid efflux.	got7fsn_ti	up regulation of phospholipid export|activation of phospholipid export|positive regulation of phospholipid export|up-regulation of phospholipid efflux|up regulation of phospholipid efflux|upregulation of phospholipid export|activation of phospholipid efflux|upregulation of phospholipid efflux|up-regulation of phospholipid export						sjp	2014-05-08T14:55:22Z						biological_process											owl:Class	
GO:2000178	biolink:NamedThing	negative regulation of neural precursor cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.	got7fsn_ti							dph	2010-10-13T12:40:43Z						biological_process											owl:Class	
GO:0055103	biolink:NamedThing	ligase regulator activity	Binds to and modulates the activity of a ligase.	got7fsn_ti														molecular_function											owl:Class	
GO:0060377	biolink:NamedThing	negative regulation of mast cell differentiation	Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	got7fsn_ti														biological_process											owl:Class	
GO:1902335	biolink:NamedThing	obsolete positive chemotaxis involved in neuron migration	OBSOLETE. Any positive chemotaxis that is involved in neuron migration.	got7fsn_ti	chemoattraction involved in neuron chemotaxis|chemoattraction involved in neuron guidance|positive chemotaxis involved in neuron guidance|positive chemotaxis involved in neuron chemotaxis|chemoattraction involved in neuron migration|positive chemotaxis involved in neuronal migration|positive chemotaxis involved in neuron migration|chemoattraction involved in neuronal migration				This term was obsoleted at the TermGenie Gatekeeper stage.		rl	2013-07-29T12:52:01Z		True				biological_process											owl:Class	
GO:1903610	biolink:NamedThing	regulation of calcium-dependent ATPase activity	Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity.	got7fsn_ti							sl	2014-11-18T00:42:49Z						biological_process											owl:Class	
GO:0006860	biolink:NamedThing	extracellular amino acid transport	The directed extracellular movement of amino acids.	got7fsn_ti														biological_process											owl:Class	
GO:0046590	biolink:NamedThing	obsolete embryonic leg morphogenesis	OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands.	got7fsn_ti	embryonic leg morphogenesis				This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0030326|GO:0035116				True				biological_process											owl:Class	
GO:0050987	biolink:NamedThing	obsolete enzyme active site formation via O-sulfo-L-serine	OBSOLETE. The transient sulfation of peptidyl-serine to form O-sulfo-L-serine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it was created by error: O-sulfo-L-serine is a post-translational modification, see PMID:14752058.					True		RESID:AA0361		biological_process											owl:Class	
GO:1902161	biolink:NamedThing	positive regulation of cyclic nucleotide-gated ion channel activity	Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.	got7fsn_ti	upregulation of cyclic nucleotide activated ion channel activity|up-regulation of cyclic nucleotide activated ion channel activity|up-regulation of cyclic nucleotide gated ion channel activity|activation of cyclic nucleotide-activated ion channel activity|upregulation of cyclic nucleotide-gated ion channel activity|activation of cyclic nucleotide-gated ion channel activity|up-regulation of cyclic nucleotide-gated ion channel activity|activation of cyclic nucleotide activated ion channel activity|up regulation of cyclic nucleotide gated ion channel activity|up regulation of cyclic nucleotide-gated ion channel activity|up regulation of cyclic nucleotide-activated ion channel activity|up regulation of cyclic nucleotide activated ion channel activity|positive regulation of cyclic nucleotide gated ion channel activity|up-regulation of cyclic nucleotide-activated ion channel activity|activation of cyclic nucleotide gated ion channel activity|upregulation of cyclic nucleotide-activated ion channel activity|positive regulation of cyclic nucleotide activated ion channel activity|upregulation of cyclic nucleotide gated ion channel activity|positive regulation of cyclic nucleotide-activated ion channel activity						sl	2013-05-21T19:24:48Z						biological_process											owl:Class	
GO:0046244	biolink:NamedThing	salicylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.	got7fsn_ti	salicylic acid catabolism|salicylic acid degradation|salicylic acid breakdown													biological_process											owl:Class	
GO:1904039	biolink:NamedThing	negative regulation of iron export across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	negative regulation of ferrous iron export|inhibition of iron(2+) export|downregulation of iron(2+) export|downregulation of ferrous iron export|down regulation of iron(2+) export|down regulation of ferrous iron export|down-regulation of iron(2+) export|inhibition of ferrous iron export|negative regulation of iron(2+) export|down-regulation of ferrous iron export						kom	2015-03-16T15:36:43Z						biological_process											owl:Class	
UBERON:0001555	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002045	biolink:NamedThing	regulation of cell adhesion involved in intussusceptive angiogenesis	The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis.	got7fsn_ti														biological_process											owl:Class	
GO:1902642	biolink:NamedThing	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.	got7fsn_ti	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process						di	2014-01-21T17:54:23Z						biological_process											owl:Class	
GO:1905243	biolink:NamedThing	cellular response to 3,3',5-triiodo-L-thyronine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.	got7fsn_ti	cellular response to Liothyronine|cellular response to Liothyroninum|cellular response to Liothyronin						sl	2016-06-08T17:42:12Z						biological_process											owl:Class	
GO:0036044	biolink:NamedThing	obsolete protein malonylation	OBSOLETE. The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.	got7fsn_ti	protein malonylation			GO:0044394	This term was made obsolete because it accidentally shared the same ID as negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway by negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity. New id is GO:0044394.					True				biological_process											owl:Class	
GO:1901598	biolink:NamedThing	(-)-pinoresinol metabolic process	The chemical reactions and pathways involving (-)-pinoresinol.	got7fsn_ti	(-)-pinoresinol metabolism						tb	2012-11-08T01:15:57Z						biological_process											owl:Class	
GO:1900714	biolink:NamedThing	negative regulation of violaceol I biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process.	got7fsn_ti	negative regulation of violaceol I biosynthesis|down-regulation of violaceol I synthesis|down-regulation of violaceol I biosynthetic process|down-regulation of violaceol I anabolism|downregulation of violaceol I biosynthesis|inhibition of violaceol I biosynthesis|downregulation of violaceol I synthesis|down regulation of violaceol I formation|downregulation of violaceol I formation|down regulation of violaceol I synthesis|inhibition of violaceol I biosynthetic process|down regulation of violaceol I biosynthesis|down-regulation of violaceol I formation|down regulation of violaceol I biosynthetic process|negative regulation of violaceol I formation|down-regulation of violaceol I biosynthesis|inhibition of violaceol I anabolism|down regulation of violaceol I anabolism|negative regulation of violaceol I synthesis|downregulation of violaceol I anabolism|negative regulation of violaceol I anabolism|downregulation of violaceol I biosynthetic process|inhibition of violaceol I formation|inhibition of violaceol I synthesis						di	2012-05-22T05:04:33Z						biological_process											owl:Class	
GO:0051815	biolink:NamedThing	obsolete migration in other organism involved in symbiotic interaction	OBSOLETE. The directional movement of an organism from one place to another within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	migration in other organism during symbiotic interaction|migration within other organism during symbiotic interaction				This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:0035414	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032948	biolink:NamedThing	regulation of alpha-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans.	got7fsn_ti	regulation of alpha-glucan metabolism													biological_process											owl:Class	
GO:0090354	biolink:NamedThing	regulation of auxin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.	got7fsn_ti	regulation of auxin metabolism						tb	2010-06-29T01:51:18Z						biological_process											owl:Class	
GO:1903203	biolink:NamedThing	regulation of oxidative stress-induced neuron death	Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron death.	got7fsn_ti	regulation of neuronal cell death in response to oxidative stress|regulation of neuron death in response to oxidative stress						bf	2014-07-21T16:17:30Z						biological_process											owl:Class	
GO:0005211	biolink:NamedThing	obsolete plasma glycoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	plasma glycoprotein				This term was made obsolete because it describes modification and presence in body fluids rather than an activity.					True				molecular_function											owl:Class	
GO:1900661	biolink:NamedThing	regulation of emericellamide A biosynthetic process	Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process.	got7fsn_ti	regulation of emericellamide A formation|regulation of emericellamide A biosynthesis|regulation of emericellamide A anabolism|regulation of emericellamide A synthesis						di	2012-05-22T04:13:07Z						biological_process											owl:Class	
GO:0003082	biolink:NamedThing	obsolete positive regulation of renal output by angiotensin	OBSOLETE. Any process in which angiotensin directly increases the rate of natriuresis and diuresis in the kidney.	got7fsn_ti	angiotensin mediated positive regulation of renal output|positive regulation of renal output by angiotensin|angiotensin-mediated positive regulation of renal output				This term was made obsolete because the term is misleading.					True				biological_process											owl:Class	
GO:0086020	biolink:NamedThing	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	got7fsn_ti	gap junction channel activity involved in sinus node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in SA node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in sinoatrial node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in SAN cell-atrial cardiomyocyte electrical coupling						tb	2011-11-11T02:08:19Z						molecular_function											owl:Class	
GO:1905644	biolink:NamedThing	regulation of FACT complex assembly	Any process that modulates the frequency, rate or extent of FACT complex assembly.	got7fsn_ti	regulation of FACT complex formation|regulation of Facilitates chromatin transcription complex assembly|regulation of Facilitates chromatin transcription complex formation						pga	2016-11-07T09:14:06Z						biological_process											owl:Class	
GO:0046140	biolink:NamedThing	corrin biosynthetic process	The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.	got7fsn_ti	corrin formation|corrin synthesis|corrin anabolism|corrin biosynthesis													biological_process											owl:Class	
GO:1901522	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus.	got7fsn_ti	stimulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|activation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|stimulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of global transcription from Pol II promoter involved in cellular response to chemical stimulus|upregulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|activation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up-regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|upregulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of transcription from Pol II promoter involved in cellular response to chemical stimulus|up regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus						al	2012-10-19T08:25:05Z						biological_process											owl:Class	
PO:0009006	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090347	biolink:NamedThing	regulation of cellular organohalogen metabolic process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.	got7fsn_ti							tb	2010-06-02T10:36:42Z						biological_process											owl:Class	
GO:1901791	biolink:NamedThing	3-(2,3-dihydroxyphenyl)propanoate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate.	got7fsn_ti	3-(2,3-dihydroxyphenyl)propanoate breakdown|3-(2,3-dihydroxyphenyl)propanoate degradation|3-(2,3-dihydroxyphenyl)propanoate catabolism						yaf	2013-01-16T11:41:02Z						biological_process											owl:Class	
GO:1901064	biolink:NamedThing	syringal lignin metabolic process	The chemical reactions and pathways involving syringal lignin.	got7fsn_ti	syringal lignin metabolism|S-lignin metabolic process						tt	2012-06-29T03:48:11Z						biological_process											owl:Class	
GO:0055090	biolink:NamedThing	acylglycerol homeostasis	Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell.	got7fsn_ti	glyceride homeostasis													biological_process											owl:Class	
GO:0002712	biolink:NamedThing	regulation of B cell mediated immunity	Any process that modulates the frequency, rate, or extent of B cell mediated immunity.	got7fsn_ti	regulation of B lymphocyte mediated immunity|regulation of B-lymphocyte mediated immunity|regulation of B-cell mediated immunity													biological_process											owl:Class	
GO:1903846	biolink:NamedThing	positive regulation of cellular response to transforming growth factor beta stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.	got7fsn_ti	up-regulation of cellular response to TGFbeta stimulus|up regulation of cellular response to TGFbeta stimulus|up-regulation of cellular response to TGF-beta stimulus|activation of cellular response to TGFbeta stimulus|up regulation of cellular response to TGF-beta stimulus|activation of cellular response to TGF-beta stimulus|up regulation of cellular response to transforming growth factor beta stimulus|up-regulation of cellular response to transforming growth factor beta stimulus|upregulation of cellular response to TGF-beta stimulus|upregulation of cellular response to transforming growth factor beta stimulus|upregulation of cellular response to TGFbeta stimulus|positive regulation of cellular response to TGFbeta stimulus|activation of cellular response to transforming growth factor beta stimulus|positive regulation of cellular response to TGF-beta stimulus						rph	2015-01-23T11:25:30Z						biological_process											owl:Class	
GO:0045645	biolink:NamedThing	positive regulation of eosinophil differentiation	Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.	got7fsn_ti	up regulation of eosinophil differentiation|stimulation of eosinophil differentiation|up-regulation of eosinophil differentiation|activation of eosinophil differentiation|upregulation of eosinophil differentiation													biological_process											owl:Class	
GO:0010683	biolink:NamedThing	tricyclic triterpenoid metabolic process	The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.	got7fsn_ti	tricyclic triterpenoid metabolism													biological_process											owl:Class	
GO:0010733	biolink:NamedThing	positive regulation of protein glutathionylation	Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.	got7fsn_ti	positive regulation of protein amino acid glutathionylation													biological_process											owl:Class	
GO:0003436	biolink:NamedThing	regulation of cell adhesion involved in growth plate cartilage morphogenesis	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone.	got7fsn_ti							dph	2009-12-22T01:28:15Z						biological_process											owl:Class	
GO:0038073	biolink:NamedThing	obsolete MAP kinase kinase kinase activity involved in conjugation with cellular fusion	OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall biogenesis.	got7fsn_ti	MAPKKK activity involved in conjugation with cellular fusion|MAP3K activity involved in conjugation with cellular fusion				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:31:57Z		True				molecular_function											owl:Class	
GO:0060966	biolink:NamedThing	regulation of gene silencing by RNA	Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.	got7fsn_ti							dph	2009-10-05T03:17:02Z						biological_process											owl:Class	
GO:0006751	biolink:NamedThing	glutathione catabolic process	The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.	got7fsn_ti	glutathione catabolism|glutathione degradation|glutathione breakdown													biological_process											owl:Class	
GO:2000914	biolink:NamedThing	positive regulation of galactoglucomannan catabolic process	Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process.	got7fsn_ti	positive regulation of galactoglucomannan catabolism						tt	2011-07-29T07:51:50Z						biological_process											owl:Class	
GO:1901229	biolink:NamedThing	regulation of non-canonical Wnt signaling pathway via JNK cascade	Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.	got7fsn_ti	regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|regulation of non-canonical Wnt-activated signaling pathway via JNK cascade						vk	2012-08-07T14:14:16Z						biological_process											owl:Class	
GO:1902830	biolink:NamedThing	negative regulation of spinal cord association neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation.	got7fsn_ti	down-regulation of spinal cord association neuron differentiation|downregulation of spinal cord association neuron differentiation|inhibition of spinal cord dorsal interneuron differentiation|negative regulation of spinal cord dorsal interneuron differentiation|downregulation of spinal cord dorsal interneuron differentiation|down regulation of spinal cord association neuron differentiation|inhibition of spinal cord association neuron differentiation|down regulation of spinal cord dorsal interneuron differentiation|down-regulation of spinal cord dorsal interneuron differentiation						mr	2014-03-31T17:11:55Z						biological_process											owl:Class	
GO:1900068	biolink:NamedThing	negative regulation of cellular response to alkaline pH	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity.	got7fsn_ti	negative regulation of cellular response to basic pH|downregulation of cellular response to basic pH|down-regulation of cellular response to alkalinity|down-regulation of cellular response to basic pH|down regulation of cellular response to alkalinity|inhibition of cellular response to alkaline pH|downregulation of cellular response to alkalinity|inhibition of cellular response to basic pH|down regulation of cellular response to alkaline pH|down regulation of cellular response to basic pH|down-regulation of cellular response to alkaline pH|downregulation of cellular response to alkaline pH|inhibition of cellular response to alkalinity|negative regulation of cellular response to alkalinity						pr	2012-01-26T02:35:03Z						biological_process											owl:Class	
GO:2001295	biolink:NamedThing	malonyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.	got7fsn_ti	malonyl-CoA biosynthesis|malonyl-CoA formation|malonyl-CoA anabolism|malonyl-CoA synthesis						pr	2012-02-14T02:23:21Z						biological_process											owl:Class	
GO:0045980	biolink:NamedThing	negative regulation of nucleotide metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.	got7fsn_ti	inhibition of nucleotide metabolic process|downregulation of nucleotide metabolic process|negative regulation of nucleotide metabolism|down-regulation of nucleotide metabolic process|down regulation of nucleotide metabolic process													biological_process											owl:Class	
GO:0019507	biolink:NamedThing	pyridine metabolic process	The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.	got7fsn_ti	pyridine metabolism													biological_process											owl:Class	
GO:0044136	biolink:NamedThing	obsolete development of symbiont on or near host rhizosphere	OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that this term represents both a process and a component		jl	2009-08-04T04:18:35Z		True				biological_process											owl:Class	
GO:1905533	biolink:NamedThing	negative regulation of leucine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane.	got7fsn_ti	negative regulation of leucine import into cell|down-regulation of L-leucine import into cell|downregulation of leucine import into cell|down-regulation of leucine import into cell|inhibition of L-leucine import into cell|inhibition of leucine import into cell|down regulation of L-leucine import into cell|downregulation of L-leucine import into cell|down regulation of leucine import into cell|negative regulation of L-leucine import into cell						vw	2016-10-05T21:08:01Z			GO:1903129			biological_process											owl:Class	
GO:1903993	biolink:NamedThing	obsolete negative regulation of protein stabilization	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein stabilization.	got7fsn_ti	down regulation of lysosomal protein stabilization|down-regulation of protein stabilization|inhibition of positive regulation of protein stability|negative regulation of lysosomal protein stabilization|downregulation of lysosomal protein stabilization|downregulation of protein sequestering|down-regulation of protein stabilization activity|negative regulation of protein stabilization activity|down regulation of protein stabilization|negative regulation of protein stabilization|downregulation of protein stabilization|down regulation of protein sequestering|down-regulation of protein sequestering|inhibition of protein stabilization|downregulation of positive regulation of protein stability|negative regulation of protein sequestering|negative regulation of positive regulation of protein stability|down-regulation of lysosomal protein stabilization|inhibition of lysosomal protein stabilization|down regulation of protein stabilization activity|down-regulation of positive regulation of protein stability|inhibition of protein stabilization activity|inhibition of protein sequestering|downregulation of protein stabilization activity|down regulation of positive regulation of protein stability				This term was made obsolete because it was created in error.	GO:0031648	pga	2015-03-05T13:32:55Z		True				biological_process											owl:Class	
GO:0048787	biolink:NamedThing	presynaptic active zone membrane	The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.	got7fsn_ti	pre-synaptic active zone membrane|active zone pre-synaptic plasma membrane|active zone presynaptic plasma membrane|active zone plasma membrane											NIF_Subcellular:sao2038461087		cellular_component											owl:Class	
GO:1905180	biolink:NamedThing	positive regulation of cardiac muscle tissue regeneration	Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration.	got7fsn_ti	up-regulation of cardiac muscle tissue regeneration|activation of cardiac muscle tissue regeneration|up regulation of cardiac muscle tissue regeneration|upregulation of cardiac muscle tissue regeneration						rph	2016-05-05T11:31:06Z						biological_process											owl:Class	
GO:0052355	biolink:NamedThing	obsolete catabolism by host of symbiont cell wall cellulose	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1902965	biolink:NamedThing	regulation of protein localization to early endosome	Any process that modulates the frequency, rate or extent of protein localization to early endosome.	got7fsn_ti	regulation of protein localisation in early endosome|regulation of protein localisation to early endosome|regulation of protein localization in early endosome						sjp	2014-05-06T09:28:24Z						biological_process											owl:Class	
GO:1903165	biolink:NamedThing	response to polycyclic arene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.	got7fsn_ti							mr	2014-07-09T18:32:59Z						biological_process											owl:Class	
GO:2000424	biolink:NamedThing	positive regulation of eosinophil chemotaxis	Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis.	got7fsn_ti							bf	2011-02-24T01:17:35Z						biological_process											owl:Class	
GO:0005180	biolink:NamedThing	obsolete peptide hormone	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peptide hormone				This term was made obsolete because it describes a type of hormone rather than a molecular function.	GO:0005179				True				molecular_function											owl:Class	
GO:2000023	biolink:NamedThing	regulation of lateral root development	Any process that modulates the frequency, rate or extent of lateral root development.	got7fsn_ti							tb	2010-08-05T11:24:50Z						biological_process											owl:Class	
GO:0032343	biolink:NamedThing	aldosterone catabolic process	The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.	got7fsn_ti														biological_process											owl:Class	
GO:0048153	biolink:NamedThing	obsolete S100 alpha biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.	got7fsn_ti	S100 alpha biosynthesis|S100 alpha anabolism|S100 alpha formation|S100 alpha synthesis	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0001975	biolink:NamedThing	response to amphetamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.	got7fsn_ti														biological_process											owl:Class	
GO:0071438	biolink:NamedThing	obsolete invadopodium membrane	OBSOLETE. The portion of the plasma membrane surrounding an invadopodium.	got7fsn_ti					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		mah	2009-12-16T03:00:30Z		True				cellular_component											owl:Class	
GO:1900471	biolink:NamedThing	obsolete negative regulation of inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of inositol biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of vitamin Bh biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of myo-inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of vitamin Bh biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of myo-inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T08:13:23Z		True				biological_process											owl:Class	
CL:1000042	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042072	biolink:NamedThing	obsolete cell adhesion receptor inhibitor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cell adhesion receptor inhibitor activity				This term was made obsolete because it represents a gene product.	GO:0007162|GO:0005102				True				molecular_function											owl:Class	
GO:1904821	biolink:NamedThing	chloroplast disassembly	The disaggregation of a chloroplast into its constituent components.	got7fsn_ti	chloroplast degradation				The disaggregation of a chloroplast into its constituent components.		lr	2015-11-19T00:41:18Z						biological_process											owl:Class	
GO:0110063	biolink:NamedThing	positive regulation of angiotensin-activated signaling pathway	Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway.	got7fsn_ti							kmv	2017-10-26T17:47:37Z						biological_process											owl:Class	
GO:1905144	biolink:NamedThing	response to acetylcholine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.	got7fsn_ti							dos	2016-04-14T08:54:49Z						biological_process											owl:Class	
OBO:GOCHE_35610	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044590	biolink:NamedThing	iron-sulfur-molybdenum cofactor binding	Binding to iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.	got7fsn_ti	FeMo co binding|FeMoco binding						jl	2012-04-26T02:27:39Z						molecular_function											owl:Class	
GO:0010607	biolink:NamedThing	negative regulation of cytoplasmic mRNA processing body assembly	Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.	got7fsn_ti														biological_process											owl:Class	
GO:0046318	biolink:NamedThing	negative regulation of glucosylceramide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.	got7fsn_ti	negative regulation of glucosylceramide biosynthesis|negative regulation of glucosylceramide anabolism|negative regulation of glucosylceramide synthesis|inhibition of glucosylceramide biosynthetic process|downregulation of glucosylceramide biosynthetic process|negative regulation of glucosylceramide formation|down-regulation of glucosylceramide biosynthetic process|down regulation of glucosylceramide biosynthetic process													biological_process											owl:Class	
GO:1902048	biolink:NamedThing	neosartoricin metabolic process	The chemical reactions and pathways involving neosartoricin.	got7fsn_ti	neosartoricin metabolism						di	2013-04-08T20:31:02Z						biological_process											owl:Class	
GO:1904021	biolink:NamedThing	negative regulation of G protein-coupled receptor internalization	Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.	got7fsn_ti	down regulation of G-protein coupled receptor internalization|inhibition of G-protein coupled receptor internalization|down-regulation of G-protein coupled receptor internalization|downregulation of G-protein coupled receptor internalization|negative regulation of G-protein coupled receptor internalization						pga	2015-03-10T17:10:50Z						biological_process											owl:Class	
GO:1903353	biolink:NamedThing	regulation of nucleus organization	Any process that modulates the frequency, rate or extent of nucleus organization.	got7fsn_ti	regulation of nuclear organisation|regulation of nuclear organization and biogenesis|regulation of nuclear organization|regulation of nucleus organization and biogenesis|regulation of nuclear morphology						hjd	2014-08-20T19:36:16Z						biological_process											owl:Class	
GO:1900928	biolink:NamedThing	positive regulation of L-threonine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-threonine import into cell.	got7fsn_ti	positive regulation of L-threonine uptake|up-regulation of L-threonine import|activation of L-threonine import|up-regulation of L-threonine uptake|upregulation of L-threonine uptake|activation of L-threonine uptake|up regulation of L-threonine import|positive regulation of L-threonine import|upregulation of L-threonine import|up regulation of L-threonine uptake						al	2012-06-13T07:42:00Z						biological_process											owl:Class	
GO:0015383	biolink:NamedThing	sulfate:bicarbonate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out).	got7fsn_ti	sulphate:bicarbonate antiporter activity													molecular_function											owl:Class	
GO:0120150	biolink:NamedThing	regulation of mitotic actomyosin contractile ring disassembly	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.	got7fsn_ti	regulation of mitotic CAR disassembly|regulation of mitotic constriction ring disassembly|regulation of mitotic contractile actomyosin ring disassembly|regulation of mitotic actomyosin ring disassembly|regulation of mitotic cytokinetic ring disassembly						krc	2018-04-24T15:06:28Z						biological_process											owl:Class	
GO:0071891	biolink:NamedThing	N-terminal peptidyl-proline dimethylation involved in translation	An N-terminal peptidyl-proline dimethylation process that contributes to translation.	got7fsn_ti							mah	2010-09-14T02:19:40Z						biological_process											owl:Class	
GO:0017078	biolink:NamedThing	obsolete Hsc70 protein regulator activity	OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsc70.	got7fsn_ti	Hsc70 interacting protein|Hsc70 protein regulator activity			GO:0031072	This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70 protein activity'.	GO:0051082|GO:0051787|GO:0006457				True				molecular_function											owl:Class	
GO:2000702	biolink:NamedThing	regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.	got7fsn_ti	regulation of FGFR signaling pathway of ureteric bud formation|regulation of FGF receptor signaling pathway of ureteric bud formation|regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|regulation of FGF receptor signalling pathway of ureteric bud formation						yaf	2011-05-25T09:48:15Z						biological_process											owl:Class	
GO:0106288	biolink:NamedThing	regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA	Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.	got7fsn_ti							hjd	2020-08-13T17:06:31Z						biological_process											owl:Class	
CHEBI:29805	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000160	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in heart morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.	got7fsn_ti							dph	2010-10-05T01:03:25Z						biological_process											owl:Class	
GO:2000983	biolink:NamedThing	regulation of ATP citrate synthase activity	Any process that modulates the frequency, rate or extent of ATP citrate synthase activity.	got7fsn_ti	regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|regulation of citric cleavage enzyme activity|regulation of ATP citrate (pro-S)-lyase activity|regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|regulation of ATP-citric lyase activity|regulation of citrate-ATP lyase activity|regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|regulation of ATP-citrate (pro-S)-lyase activity|regulation of citrate cleavage enzyme activity|regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|regulation of adenosine triphosphate citrate lyase activity|regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|regulation of ATP-citrate (pro-S-)-lyase activity						vk	2011-08-04T03:15:24Z						biological_process											owl:Class	
GO:1904467	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004323	biolink:NamedThing	obsolete multicopper ferroxidase iron transport mediator activity	OBSOLETE. Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.	got7fsn_ti	multicopper ferroxidase iron transport mediator activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0004322|GO:0005381				True				molecular_function											owl:Class	
GO:0075108	biolink:NamedThing	obsolete negative regulation by symbiont of host adenylate cyclase activity	OBSOLETE. Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	Negative regulation by symbiont of host adenylylcyclase activity|Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity|Negative regulation by symbiont of host adenyl cyclase activity|Negative regulation by symbiont of host ATP pyrophosphate-lyase activity|Negative regulation by symbiont of host cAMP generating peptide activity|Negative regulation by symbiont of host 3',5'-cyclic AMP synthetase activity|Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity|Negative regulation by symbiont of host adenylyl cyclase activity				This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1901767	biolink:NamedThing	carbapenem metabolic process	The chemical reactions and pathways involving carbapenem.	got7fsn_ti	carbapenem metabolism						yaf	2013-01-15T10:08:57Z						biological_process											owl:Class	
GO:1905663	biolink:NamedThing	positive regulation of telomerase RNA reverse transcriptase activity	Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity.	got7fsn_ti	activation of telomerase RNA reverse transcriptase activity|up-regulation of telomerase, catalyst|up-regulation of telomerase RNA reverse transcriptase activity|up regulation of telomerase RNA reverse transcriptase activity|upregulation of telomerase RNA reverse transcriptase activity|upregulation of telomerase, catalyst|positive regulation of telomerase, catalyst|activation of telomerase, catalyst|up regulation of telomerase, catalyst						nc	2016-11-09T16:55:35Z						biological_process											owl:Class	
GO:1905085	biolink:NamedThing	regulation of bioluminescence	Any process that modulates the frequency, rate or extent of bioluminescence.	got7fsn_ti							rph	2016-03-29T07:51:07Z						biological_process											owl:Class	
GO:0006211	biolink:NamedThing	5-methylcytosine catabolic process	The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA.	got7fsn_ti	5-methylcytosine breakdown|5-methylcytosine degradation|5-methylcytosine catabolism													biological_process											owl:Class	
GO:0031243	biolink:NamedThing	intrinsic component of external side of cell outer membrane	The component of the cell outer membrane consisting of the gene products and protein complexes that penetrate the external side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor.	got7fsn_ti	intrinsic to external leaflet of cell outer membrane|intrinsic to external side of outer membrane|intrinsic to external side of cell outer membrane													cellular_component											owl:Class	
GO:0097553	biolink:NamedThing	calcium ion transmembrane import into cytosol	A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.	got7fsn_ti	calcium transmembrane import into cytosol						pr	2014-01-23T11:05:13Z						biological_process											owl:Class	
GO:1901304	biolink:NamedThing	regulation of spermidine biosynthetic process	Any process that modulates the frequency, rate or extent of spermidine biosynthetic process.	got7fsn_ti	regulation of spermidine biosynthesis|regulation of spermidine formation|regulation of spermidine synthesis|regulation of spermidine anabolism						pm	2012-08-21T13:58:23Z						biological_process											owl:Class	
GO:0098523	biolink:NamedThing	neuromuscular junction of myotube	A neuromuscular junction in which the target muscle cell is a myotube.	got7fsn_ti					In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes.		dos	2013-10-14T12:05:12Z						cellular_component											owl:Class	
GO:1901272	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconic acid metabolic process	The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid.	got7fsn_ti	2-dehydro-3-deoxy-D-gluconic acid metabolism						yaf	2012-08-17T14:46:15Z						biological_process											owl:Class	
GO:1900542	biolink:NamedThing	regulation of purine nucleotide metabolic process	Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.	got7fsn_ti	regulation of purine metabolism|regulation of purine nucleotide metabolism|regulation of purine metabolic process						krc	2012-05-11T05:43:15Z						biological_process											owl:Class	
GO:0046257	biolink:NamedThing	obsolete anaerobic 2,4,6-trinitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen.	got7fsn_ti	anaerobic 2,4,6-trinitrotoluene synthesis|anaerobic 2,4,6-trinitrotoluene anabolism|anaerobic 2,4,6-trinitrotoluene formation|anaerobic 2,4,6-trinitrotoluene biosynthetic process|anaerobic 2,4,6-trinitrotoluene biosynthesis			GO:0018975	This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1902854	biolink:NamedThing	positive regulation of nuclear migration during mitotic telophase	Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase.	got7fsn_ti	up regulation of nuclear migration during mitotic telophase|upregulation of nuclear migration during mitotic telophase|activation of nuclear migration during mitotic telophase|up-regulation of nuclear migration during mitotic telophase						vw	2014-04-02T15:36:06Z						biological_process											owl:Class	
GO:0150074	biolink:NamedThing	positive regulation of protein-glutamine gamma-glutamyltransferase activity	Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.	got7fsn_ti							bc	2018-07-25T10:08:19Z						biological_process											owl:Class	
GO:0000116	biolink:NamedThing	obsolete regulation of transcription involved in G2-phase of mitotic cell cycle	OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G2 phase of the mitotic cell cycle.	got7fsn_ti	regulation of transcription involved in G2-phase of mitotic cell cycle|G2-specific transcription in mitotic cell cycle|regulation of transcription from RNA polymerase II during G2-phase of mitotic cell cycle				This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0000117|GO:0006357				True				biological_process											owl:Class	
GO:0006227	biolink:NamedThing	dUDP biosynthetic process	The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).	got7fsn_ti	dUDP biosynthesis|dUDP anabolism|dUDP formation|dUDP synthesis													biological_process											owl:Class	
GO:0052450	biolink:NamedThing	obsolete modulation by organism of induced systemic resistance in symbiont	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of induced systemic resistance in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1901274	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid.	got7fsn_ti	2-dehydro-3-deoxy-D-gluconic acid anabolism|2-dehydro-3-deoxy-D-gluconic acid biosynthesis|2-dehydro-3-deoxy-D-gluconic acid synthesis|2-dehydro-3-deoxy-D-gluconic acid formation						yaf	2012-08-17T14:46:44Z						biological_process											owl:Class	
GO:0019261	biolink:NamedThing	1,4-dichlorobenzene catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring.	got7fsn_ti	1,4-dichlorobenzene degradation|1,4-dichlorobenzene breakdown|1,4-dichlorobenzene catabolism											MetaCyc:14DICHLORBENZDEG-PWY		biological_process											owl:Class	
GO:0045831	biolink:NamedThing	negative regulation of light-activated channel activity	Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity.	got7fsn_ti	downregulation of light-activated channel activity|down-regulation of light-activated channel activity|down regulation of light-activated channel activity|inhibition of light-activated channel activity													biological_process											owl:Class	
GO:1905811	biolink:NamedThing	negative regulation of excitatory synapse pruning	Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning.	got7fsn_ti	regulation of synapse disassembly|down regulation of excitatory synapse disassembly|regulation of synapse clearance|regulation of synapse elimination|inhibition of excitatory synapse disassembly|regulation of synapse removal|down-regulation of excitatory synapse disassembly|downregulation of excitatory synapse disassembly						tb	2017-01-12T02:38:36Z						biological_process											owl:Class	
GO:0075099	biolink:NamedThing	obsolete modulation by host of symbiont protein kinase-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0042046	biolink:NamedThing	W-molybdopterin cofactor metabolic process	The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.	got7fsn_ti	W-molybdopterin cofactor metabolism|Moco metabolism|Moco metabolic process													biological_process											owl:Class	
GO:2000119	biolink:NamedThing	negative regulation of sodium-dependent phosphate transport	Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport.	got7fsn_ti							jl	2010-09-23T01:35:03Z						biological_process											owl:Class	
GO:0032272	biolink:NamedThing	negative regulation of protein polymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.	got7fsn_ti	down-regulation of protein polymerization|down regulation of protein polymerization|downregulation of protein polymerization|inhibition of protein polymerization													biological_process											owl:Class	
GO:2000620	biolink:NamedThing	positive regulation of histone H4-K16 acetylation	Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation.	got7fsn_ti	positive regulation of histone H4 acetylation at K16						vk	2011-04-18T03:19:30Z						biological_process											owl:Class	
GO:1900891	biolink:NamedThing	negative regulation of pentadecane metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process.	got7fsn_ti	downregulation of pentadecane metabolism|down regulation of pentadecane metabolism|down regulation of pentadecane metabolic process|down-regulation of pentadecane metabolism|down-regulation of pentadecane metabolic process|downregulation of pentadecane metabolic process|negative regulation of pentadecane metabolism|inhibition of pentadecane metabolism|inhibition of pentadecane metabolic process						tt	2012-06-13T03:06:11Z						biological_process											owl:Class	
GO:1901463	biolink:NamedThing	regulation of tetrapyrrole biosynthetic process	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process.	got7fsn_ti	regulation of tetrapyrrole anabolism|regulation of tetrapyrrole formation|regulation of tetrapyrrole biosynthesis|regulation of tetrapyrrole synthesis						tt	2012-10-02T14:34:14Z						biological_process											owl:Class	
GO:0009771	biolink:NamedThing	obsolete primary charge separation in photosystem II	OBSOLETE. Energized reaction-center P680 chlorophylls on photosystem II donate an electron to a loosely bound acceptor molecule, the quinone Q, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.	got7fsn_ti					This term was obsoleted because it represents a mechanism, and is outside the scope of GO.					True				biological_process											owl:Class	
GO:0090388	biolink:NamedThing	phagosome-lysosome docking involved in apoptotic cell clearance	The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere.	got7fsn_ti							tb	2010-10-27T10:57:39Z						biological_process											owl:Class	
GO:0016923	biolink:NamedThing	obsolete ligand-dependent thyroid hormone receptor interactor activity	OBSOLETE. Ligand dependent interaction with the thyroid hormone receptor.	got7fsn_ti	TRIP4|ligand-dependent thyroid hormone receptor interactor activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0046966				True				molecular_function											owl:Class	
GO:0052207	biolink:NamedThing	obsolete modification of morphology or physiology of other organism via protein secreted by type III secretion system involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type III secretion system in the first organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modification of morphology or physiology of other organism via protein secreted by type III secretion system during symbiotic interaction				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
UBERON:0000057	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052245	biolink:NamedThing	obsolete negative energy taxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative energy taxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0097253	biolink:NamedThing	beta-hydroxybutyrate transmembrane transporter activity	Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.	got7fsn_ti	(R)-3-hydroxybutyrate transmembrane transporter activity|3-hydroxybutanoic acid transmembrane transporter activity						pr	2012-03-05T01:22:37Z						molecular_function											owl:Class	
GO:0009213	biolink:NamedThing	pyrimidine deoxyribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside triphosphate breakdown|pyrimidine deoxyribonucleoside triphosphate catabolism|pyrimidine deoxyribonucleoside triphosphate degradation													biological_process											owl:Class	
GO:1904305	biolink:NamedThing	negative regulation of gastro-intestinal system smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.	got7fsn_ti	downregulation of gastro-intestinal system smooth muscle contraction|down regulation of gastro-intestinal system smooth muscle contraction|inhibition of gastro-intestinal system smooth muscle contraction|down-regulation of gastro-intestinal system smooth muscle contraction						sl	2015-06-09T23:18:48Z						biological_process											owl:Class	
GO:0014038	biolink:NamedThing	regulation of Schwann cell differentiation	Any process that modulates the frequency, rate or extent of Schwann cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:2000687	biolink:NamedThing	obsolete negative regulation of rubidium ion transmembrane transporter activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transmembrane transporter activity.	got7fsn_ti	negative regulation of Rb+ transmembrane transporter activity|negative regulation of rubidium cation transmembrane transporter activity|negative regulation of rubidium transmembrane transporter activity				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-11T09:27:32Z		True				biological_process											owl:Class	
GO:0089704	biolink:NamedThing	L-glutamate transmembrane export from vacuole	The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
GO:1905621	biolink:NamedThing	positive regulation of alpha-(1->3)-fucosyltransferase activity	Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.	got7fsn_ti	activation of alpha(1,3)-fucosyltransferase activity|up-regulation of alpha(1,3)-fucosyltransferase activity|up regulation of alpha(1,3)-fucosyltransferase activity|upregulation of alpha-1,3-fucosyltransferase activity|activation of alpha-1,3-fucosyltransferase activity|activation of alpha-(1->3)-fucosyltransferase activity|upregulation of alpha(1,3)-fucosyltransferase activity|up-regulation of alpha-(1->3)-fucosyltransferase activity|up-regulation of alpha-(1,3)-fucosyltransferase activity|up regulation of alpha-(1,3)-fucosyltransferase activity|up regulation of alpha-(1->3)-fucosyltransferase activity|upregulation of alpha-(1,3)-fucosyltransferase activity|positive regulation of alpha-(1,3)-fucosyltransferase activity|activation of alpha-(1,3)-fucosyltransferase activity|up-regulation of alpha-1,3-fucosyltransferase activity|up regulation of alpha-1,3-fucosyltransferase activity|positive regulation of alpha-1,3-fucosyltransferase activity|upregulation of alpha-(1->3)-fucosyltransferase activity|positive regulation of alpha(1,3)-fucosyltransferase activity						rz	2016-10-28T14:39:52Z						biological_process											owl:Class	
GO:1903420	biolink:NamedThing	protein localization to endoplasmic reticulum tubular network	A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network.	got7fsn_ti	protein localization to tubular ER|protein localisation in endoplasmic reticulum tubular network|protein localization in endoplasmic reticulum tubular network|protein localisation to endoplasmic reticulum tubular network						mah	2014-09-08T16:03:37Z						biological_process											owl:Class	
GO:0000185	biolink:NamedThing	obsolete activation of MAPKKK activity	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).	got7fsn_ti	activation of MAP3K activity|positive regulation of MAPKKK activity|positive regulation of MAP kinase kinase kinase activity|activation of MAP kinase kinase kinase|activation of MAPKKK activity during sporulation	https://github.com/geneontology/go-ontology/issues/21307			This term was obsoleted because it represents a molecular function.	GO:0043539|GO:0000165				True				biological_process											owl:Class	
GO:1903778	biolink:NamedThing	protein localization to vacuolar membrane	A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.	got7fsn_ti	protein localisation in vacuolar membrane|protein localization in vacuolar membrane|protein localisation to vacuolar membrane						mah	2015-01-07T13:15:54Z						biological_process											owl:Class	
GO:0017074	biolink:NamedThing	obsolete procollagen N-endopeptidase activity	OBSOLETE. Catalysis of the cleavage of the N-propeptide of collagen chain alpha-1(I) at Pro-Gln and of alpha-1(II) and alpha-2(I) chains at Ala-Gln.	got7fsn_ti	aminoterminal procollagen peptidase activity|procollagen N-terminal peptidase activity|procollagen N-terminal proteinase activity|aminoprocollagen peptidase activity|type I/II procollagen N-proteinase activity|procollagen aminoterminal protease activity|procollagen N-proteinase activity|procollagen N-endopeptidase activity|procollagen aminopeptidase activity|type III procollagen			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1903241	biolink:NamedThing	U2-type prespliceosome assembly	The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome.	got7fsn_ti	major prespliceosome formation|yeast U2-type spliceosomal complex B assembly|yeast U2-type spliceosomal complex B formation|major prespliceosome assembly|mammalian U2-type spliceosomal complex A formation|GT-AG prespliceosome assembly|GT-AG prespliceosome formation|U2-type prespliceosome formation|mammalian U2-type spliceosomal complex A assembly						mah	2014-08-01T14:33:45Z						biological_process											owl:Class	
GO:1990912	biolink:NamedThing	obsolete response to microwave radiation	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microwave radiation stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-12-07T21:25:08Z		True				biological_process											owl:Class	
GO:0044239	biolink:NamedThing	obsolete salivary polysaccharide catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth.	got7fsn_ti	salivary polysaccharide degradation|salivary polysaccharide catabolism|salivary polysaccharide breakdown				The reason for obsoletion is that this term represents the location of a process, which should be captured by the relation 'occurs in'.	GO:0000272				True				biological_process											owl:Class	
GO:1903613	biolink:NamedThing	regulation of protein tyrosine phosphatase activity	Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity.	got7fsn_ti	regulation of protein-tyrosine-phosphate phosphohydrolase activity|regulation of tyrosylprotein phosphatase activity|regulation of phosphotyrosine histone phosphatase activity|regulation of phosphoprotein phosphatase (phosphotyrosine) activity|regulation of PTPase activity|regulation of [phosphotyrosine]protein phosphatase activity|regulation of PTP-phosphatase activity|regulation of phosphotyrosine protein phosphatase activity|regulation of protein phosphotyrosine phosphatase activity|regulation of phosphotyrosine phosphatase activity|regulation of tyrosine O-phosphate phosphatase activity|regulation of phosphotyrosylprotein phosphatase activity|regulation of protein-tyrosine-phosphatase activity|regulation of PPT-phosphatase activity						sl	2014-11-18T01:11:38Z						biological_process											owl:Class	
GO:0002155	biolink:NamedThing	regulation of thyroid hormone mediated signaling pathway	Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway.	got7fsn_ti	regulation of thyroid hormone mediated signalling pathway						hjd	2009-11-19T12:37:46Z						biological_process											owl:Class	
GO:0008633	biolink:NamedThing	obsolete activation of pro-apoptotic gene products	OBSOLETE. The conversion of proteins that induce or sustain apoptosis to an active form.	got7fsn_ti	induction of pro-apoptotic gene products|activation of pro-apoptotic gene products				This term was made obsolete because more specific terms were created. Additionally, the meaning of the term is ambiguous (some gene products may be involved in apoptosis, or not, depending on cell type, tissue, condition).					True				biological_process											owl:Class	
GO:1901153	biolink:NamedThing	paromomycin metabolic process	The chemical reactions and pathways involving paromomycin.	got7fsn_ti	paromomycin metabolism						yaf	2012-07-17T04:27:20Z						biological_process											owl:Class	
GO:0002579	biolink:NamedThing	positive regulation of antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.	got7fsn_ti	upregulation of antigen processing and presentation|up-regulation of antigen processing and presentation|stimulation of antigen processing and presentation|activation of antigen processing and presentation|up regulation of antigen processing and presentation													biological_process											owl:Class	
GO:1904643	biolink:NamedThing	response to curcumin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.	got7fsn_ti							sl	2015-08-31T20:38:11Z						biological_process											owl:Class	
GO:0015003	biolink:NamedThing	obsolete copper electron carrier	OBSOLETE. A copper-containing entity that serves as an electron acceptor and electron donor in an electron transport system.	got7fsn_ti	copper electron carrier			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:0005076	biolink:NamedThing	obsolete receptor signaling protein serine/threonine kinase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	receptor signalling protein serine/threonine kinase signalling protein activity|receptor signaling protein serine/threonine kinase signaling protein activity				This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556				True				molecular_function											owl:Class	
GO:0052222	biolink:NamedThing	obsolete negative aerotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative aerotaxis in response to environment of other organism|negative aerotaxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0051595	biolink:NamedThing	response to methylglyoxal	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.	got7fsn_ti	response to pyruvaldehyde													biological_process											owl:Class	
GO:1903163	biolink:NamedThing	obsolete sodium ion transmembrane transporter activity involved in sodium ion import into cell	OBSOLETE. Any sodium ion transmembrane transporter activity that is involved in sodium ion import into cell.	got7fsn_ti	sodium transporter activity involved in sodium ion import into cell|sodium ion transmembrane transporter activity involved in sodium ion import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:49Z		True				molecular_function											owl:Class	
GO:0043458	biolink:NamedThing	ethanol biosynthetic process involved in glucose fermentation to ethanol	The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, as part of the process of glucose catabolism to ethanol, CO2 and ATP.	got7fsn_ti	ethanol formation during fermentation|ethanol anabolism during fermentation|ethanol synthesis during fermentation													biological_process											owl:Class	
GO:0010953	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905687	biolink:NamedThing	regulation of diacylglycerol kinase activity	Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity.	got7fsn_ti	regulation of 1,2-diacylglycerol kinase activity|regulation of DGK activity|regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|regulation of DG kinase activity|regulation of ATP:diacylglycerol phosphotransferase activity|regulation of sn-1,2-diacylglycerol kinase activity|regulation of CTP:diacylglycerol kinase activity|regulation of arachidonoyl-specific diacylglycerol kinase activity|regulation of diacylglycerol:ATP kinase activity|regulation of diglyceride kinase activity|regulation of 1,2-diacylglycerol kinase (phosphorylating)						bc	2016-11-14T12:26:11Z						biological_process											owl:Class	
UBERON:0000011	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905885	biolink:NamedThing	positive regulation of triglyceride transport	Any process that activates or increases the frequency, rate or extent of triglyceride transport.	got7fsn_ti	positive regulation of triacylglycerol transport|activation of triglyceride transport|activation of triacylglycerol transport|up regulation of triacylglycerol transport|up-regulation of triglyceride transport|up regulation of triglyceride transport|up-regulation of triacylglycerol transport|upregulation of triglyceride transport|upregulation of triacylglycerol transport						rz	2017-01-31T11:32:47Z						biological_process											owl:Class	
GO:0048740	biolink:NamedThing	obsolete striated muscle fiber development	OBSOLETE. The process whose specific outcome is the amplification and progression of myoblasts (muscle precursor cells) into terminally differentiated multinucleated muscle fibers.	got7fsn_ti	striated muscle fiber development|striated muscle fibre development|myogenesis				This term was made obsolete because it was an unnecessary grouping term. Striated muscle comprises skeletal and cardiac muscle, but GO has opted not to group the muscle fiber development terms.					True				biological_process											owl:Class	
GO:1905768	biolink:NamedThing	negative regulation of double-stranded telomeric DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding.	got7fsn_ti	down-regulation of double-stranded telomeric DNA binding|down regulation of double-stranded telomeric DNA binding|downregulation of double-stranded telomeric DNA binding|inhibition of double-stranded telomeric DNA binding						nc	2016-12-20T15:34:07Z						biological_process											owl:Class	
GO:0071442	biolink:NamedThing	positive regulation of histone H3-K14 acetylation	Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.	got7fsn_ti	up regulation of histone H3-K14 acetylation|positive regulation of histone H3K14 acetylation|positive regulation of histone H3 acetylation at K14|stimulation of histone H3-K14 acetylation|activation of histone H3-K14 acetylation|up-regulation of histone H3-K14 acetylation|upregulation of histone H3-K14 acetylation						mah	2009-12-16T03:29:49Z						biological_process											owl:Class	
GO:1903627	biolink:NamedThing	regulation of dUTP diphosphatase activity	Any process that modulates the frequency, rate or extent of dUTP diphosphatase activity.	got7fsn_ti	regulation of desoxyuridine 5'-triphosphatase activity|regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|regulation of dUTP pyrophosphatase activity|regulation of dUTP nucleotidohydrolase activity|regulation of dUTPase activity|regulation of deoxyuridine-triphosphatase activity						sl	2014-11-20T00:00:36Z						biological_process											owl:Class	
GO:0120075	biolink:NamedThing	positive regulation of endocardial cushion cell differentiation	Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation.	got7fsn_ti							krc	2017-06-26T23:36:59Z						biological_process											owl:Class	
GO:1904432	biolink:NamedThing	regulation of ferrous iron binding	Any process that modulates the frequency, rate or extent of ferrous iron binding.	got7fsn_ti							kom	2015-07-06T13:46:30Z						biological_process											owl:Class	
GO:0120132	biolink:NamedThing	positive regulation of apoptotic process in bone marrow cell	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow.	got7fsn_ti	positive regulation of bone marrow cell apoptosis|positive regulation of programmed cell death, bone marrow cells|positive regulation of programmed cell death of bone marrow cells by apoptosis|up regulation of apoptosis in bone marrow|upregulation of apoptosis in bone marrow|up-regulation of apoptosis in bone marrow|positive regulation of bone marrow cell programmed cell death by apoptosis|positive regulation of killing of bone marrow cells|positive regulation of apoptotic process in bone marrow|positive regulation of apoptosis in bone marrow|activation of apoptosis in bone marrow						krc	2018-02-19T16:51:46Z						biological_process											owl:Class	
GO:0006573	biolink:NamedThing	valine metabolic process	The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid.	got7fsn_ti	valine metabolism													biological_process											owl:Class	
GO:0051099	biolink:NamedThing	positive regulation of binding	Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.	got7fsn_ti	up-regulation of binding|stimulation of binding|activation of binding|up regulation of binding|upregulation of binding													biological_process											owl:Class	
GO:0016562	biolink:NamedThing	protein import into peroxisome matrix, receptor recycling	The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol.	got7fsn_ti	receptor recycling during protein transport into peroxisome matrix|receptor recycling during peroxisome matrix protein import|protein transport into peroxisome matrix, receptor recycling|peroxisome matrix protein import, receptor recycling|receptor recycling during protein import into peroxisome matrix|peroxisome receptor recycling|PTS receptor recycling													biological_process											owl:Class	
GO:0062010	biolink:NamedThing	primitive palate development	The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure.	got7fsn_ti							dph	2018-02-26T23:00:48Z						biological_process											owl:Class	
GO:0015282	biolink:NamedThing	obsolete NADPH oxidase-associated cytochrome b558 hydrogen channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	NADPH oxidase-associated cytochrome b558 proton channel|NADPH oxidase-associated cytochrome b558 hydrogen channel activity				This term was made obsolete because it describes a gene product rather than a function.					True				molecular_function											owl:Class	
GO:0004880	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900457	biolink:NamedThing	regulation of brassinosteroid mediated signaling pathway	Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway.	got7fsn_ti	regulation of brassinosteroid mediated signalling						dhl	2012-05-01T06:12:04Z						biological_process											owl:Class	
GO:0070512	biolink:NamedThing	positive regulation of histone H4-K20 methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.	got7fsn_ti	up-regulation of histone H4-K20 methylation|stimulation of histone H4-K20 methylation|upregulation of histone H4-K20 methylation|up regulation of histone H4-K20 methylation|activation of histone H4-K20 methylation													biological_process											owl:Class	
GO:0017032	biolink:NamedThing	amino acid:potassium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).	got7fsn_ti	potassium:amino acid symporter activity													molecular_function											owl:Class	
GO:1901197	biolink:NamedThing	positive regulation of calcium-mediated signaling involved in cellular response to calcium ion	Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion.	got7fsn_ti	up-regulation of calcium-mediated signaling involved in response to calcium ion|up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signalling involved in cellular response to calcium ion|activation of calcium-mediated signaling involved in cellular response to Ca2+ ion|activation of calcium-mediated signaling involved in cellular response to calcium ion|stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|stimulation of calcium-mediated signaling involved in cellular response to calcium ion|up regulation of calcium-mediated signaling involved in cellular response to calcium ion|positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion|upregulation of calcium-mediated signaling involved in cellular response to calcium ion						al	2012-07-27T10:57:56Z						biological_process											owl:Class	
GO:1902278	biolink:NamedThing	positive regulation of pancreatic amylase secretion	Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion.	got7fsn_ti	upregulation of pancreatic amylase secretion|up regulation of pancreatic amylase secretion|activation of pancreatic amylase secretion|up-regulation of pancreatic amylase secretion						bf	2013-07-03T12:15:31Z						biological_process											owl:Class	
GO:0140410	biolink:NamedThing	solute:bicarbonate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + HCO3-(out) = solute(in) + HCO3-(in).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18345					pg	2020-01-07T16:58:49Z						molecular_function											owl:Class	
GO:0001926	biolink:NamedThing	positive regulation of B-1 B cell differentiation	Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.	got7fsn_ti	positive regulation of B-1 B lymphocyte differentiation|stimulation of B-1 B cell differentiation|upregulation of B-1 B cell differentiation|positive regulation of B-1 B cell development|activation of B-1 B cell differentiation|up-regulation of B-1 B cell differentiation|up regulation of B-1 B cell differentiation|positive regulation of B-1 B-lymphocyte differentiation|positive regulation of B-1 B-cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0010773	biolink:NamedThing	meiotic DNA recombinase assembly involved in meiotic gene conversion	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.	got7fsn_ti														biological_process											owl:Class	
GO:0032819	biolink:NamedThing	positive regulation of natural killer cell proliferation	Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.	got7fsn_ti	upregulation of natural killer cell proliferation|up regulation of natural killer cell proliferation|up-regulation of natural killer cell proliferation|activation of natural killer cell proliferation|stimulation of natural killer cell proliferation|positive regulation of NK cell proliferation													biological_process											owl:Class	
GO:0007245	biolink:NamedThing	obsolete activation of MAPKKK (mating sensu Saccharomyces)	OBSOLETE. Upregulation of MAPKKK activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.	got7fsn_ti	activation of MAPKKK (mating sensu Saccharomyces)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0005469	biolink:NamedThing	succinate:fumarate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out).	got7fsn_ti														molecular_function											owl:Class	
GO:1905432	biolink:NamedThing	regulation of retrograde trans-synaptic signaling by neuropeptide	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.	got7fsn_ti	regulation of neuropeptide-mediated retrograde trans-synaptic signaling						bf	2016-09-14T10:56:47Z						biological_process											owl:Class	
GO:0044448	biolink:NamedThing	obsolete cell cortex part	OBSOLETE. Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005938				True				cellular_component											owl:Class	
CHEBI:26628	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000734	biolink:NamedThing	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.	got7fsn_ti	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|negative regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|negative regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|negative regulation of GDNF receptor signaling pathway of ureteric bud formation|negative regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation						yaf	2011-06-13T11:14:44Z						biological_process											owl:Class	
GO:2000139	biolink:NamedThing	regulation of octopamine signaling pathway involved in response to food	Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food.	got7fsn_ti	regulation of octopamine signalling pathway involved in response to food						mah	2010-09-30T02:48:07Z						biological_process											owl:Class	
GO:0046635	biolink:NamedThing	positive regulation of alpha-beta T cell activation	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation.	got7fsn_ti	positive regulation of alpha-beta T lymphocyte activation|activation of alpha-beta T cell activation|up-regulation of alpha-beta T cell activation|positive regulation of alpha-beta T-cell activation|up regulation of alpha-beta T cell activation|stimulation of alpha-beta T cell activation|upregulation of alpha-beta T cell activation|positive regulation of alpha-beta T-lymphocyte activation													biological_process											owl:Class	
GO:2000059	biolink:NamedThing	negative regulation of ubiquitin-dependent protein catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process.	got7fsn_ti	negative regulation of protein ubiquitination during ubiquitin-dependent protein degradation|negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of protein degradation tagging activity|negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitination during ubiquitin-dependent protein breakdown						jl	2010-08-20T01:23:56Z						biological_process											owl:Class	
GO:2000570	biolink:NamedThing	positive regulation of T-helper 2 cell activation	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation.	got7fsn_ti	positive regulation of Th2 cell activation						ebc	2011-04-03T09:14:59Z						biological_process											owl:Class	
GO:0016771	biolink:NamedThing	obsolete transferase activity, transferring other nitrogenous groups	OBSOLETE. Catalysis of the transfer of a nitrogenous group, other than amino, amidino or oxime, from one compound (donor) to another (acceptor).	got7fsn_ti	transferase activity, transferring other nitrogenous groups				This term was made obsolete because it was an unnecessary grouping term.	GO:0016769				True				molecular_function											owl:Class	
GO:1900898	biolink:NamedThing	positive regulation of heptadecane biosynthetic process	Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process.	got7fsn_ti	up regulation of heptadecane synthesis|activation of heptadecane formation|up-regulation of heptadecane formation|up-regulation of heptadecane biosynthesis|upregulation of heptadecane synthesis|up-regulation of heptadecane biosynthetic process|positive regulation of heptadecane biosynthesis|upregulation of heptadecane formation|positive regulation of heptadecane synthesis|upregulation of heptadecane biosynthesis|up regulation of heptadecane formation|up-regulation of heptadecane synthesis|up-regulation of heptadecane anabolism|activation of heptadecane biosynthesis|activation of heptadecane anabolism|upregulation of heptadecane anabolism|upregulation of heptadecane biosynthetic process|up regulation of heptadecane biosynthesis|up regulation of heptadecane anabolism|up regulation of heptadecane biosynthetic process|activation of heptadecane biosynthetic process|activation of heptadecane synthesis|positive regulation of heptadecane formation|positive regulation of heptadecane anabolism						tt	2012-06-13T03:28:10Z						biological_process											owl:Class	
GO:0110029	biolink:NamedThing	negative regulation of meiosis I	Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.	got7fsn_ti							kmv	2017-07-12T18:47:33Z						biological_process											owl:Class	
GO:0097331	biolink:NamedThing	response to cytarabine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.	got7fsn_ti							pr	2012-06-12T10:55:29Z						biological_process											owl:Class	
GO:1905770	biolink:NamedThing	regulation of mesodermal cell differentiation	Any process that modulates the frequency, rate or extent of mesodermal cell differentiation.	got7fsn_ti	regulation of mesoderm cell differentiation						rph	2016-12-21T12:44:13Z						biological_process											owl:Class	
GO:1905653	biolink:NamedThing	positive regulation of artery morphogenesis	Any process that activates or increases the frequency, rate or extent of artery morphogenesis.	got7fsn_ti	up regulation of artery morphogenesis|upregulation of arterial morphogenesis|activation of arterial morphogenesis|up-regulation of arteriogenesis|up regulation of arterial morphogenesis|upregulation of arteriogenesis|upregulation of artery morphogenesis|up-regulation of artery morphogenesis|up-regulation of arterial morphogenesis|positive regulation of arterial morphogenesis|activation of artery morphogenesis|up regulation of arteriogenesis|activation of arteriogenesis|positive regulation of arteriogenesis						rph	2016-11-09T12:20:01Z						biological_process											owl:Class	
GO:1904428	biolink:NamedThing	negative regulation of tubulin deacetylation	Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation.	got7fsn_ti	down-regulation of tubulin deacetylation|inhibition of tubulin deacetylation|down regulation of tubulin deacetylation|downregulation of tubulin deacetylation						sart	2015-07-03T14:42:58Z						biological_process											owl:Class	
GO:0104005	biolink:NamedThing	obsolete hijacked molecular function	OBSOLETE. A function that was not selected for in the evolution of an organism, but arises from co-option by another organism, e.g. a human protein used as a virus receptor.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16741			This term was obsoleted because it was an unnecessary grouping class.		dos	2017-08-04T02:12:09Z		True				molecular_function											owl:Class	
GO:0002903	biolink:NamedThing	negative regulation of B cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.	got7fsn_ti	inhibition of B cell apoptosis|down regulation of B cell apoptosis|negative regulation of B cell apoptosis|down-regulation of B cell apoptosis|downregulation of B cell apoptosis													biological_process											owl:Class	
GO:0072468	biolink:NamedThing	obsolete signal transduction involved in cell shape checkpoint	OBSOLETE. A signal transduction process that contributes to a cell shape checkpoint.	got7fsn_ti					This term was made obsolete because it was ambiguous.		mah	2010-12-09T11:45:12Z		True				biological_process											owl:Class	
GO:0044427	biolink:NamedThing	obsolete chromosomal part	OBSOLETE. Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.	got7fsn_ti	chromosomal component|chromosome part|chromosome component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005694				True				cellular_component											owl:Class	
GO:2000964	biolink:NamedThing	negative regulation of cellooligosaccharide catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process.	got7fsn_ti	negative regulation of cellooligosaccharide catabolism						tt	2011-08-01T02:28:42Z						biological_process											owl:Class	
GO:0098971	biolink:NamedThing	anterograde dendritic transport of neurotransmitter receptor complex	The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.	got7fsn_ti														biological_process											owl:Class	
GO:0046519	biolink:NamedThing	sphingoid metabolic process	The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.	got7fsn_ti	sphingoid base metabolic process|sphingoid base metabolism|sphingoid metabolism													biological_process											owl:Class	
GO:1903938	biolink:NamedThing	cellular response to acrylamide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.	got7fsn_ti							sl	2015-02-12T22:00:34Z						biological_process											owl:Class	
GO:0019860	biolink:NamedThing	uracil metabolic process	The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.	got7fsn_ti	uracil metabolism													biological_process											owl:Class	
GO:0120183	biolink:NamedThing	positive regulation of focal adhesion disassembly	Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.	got7fsn_ti							krc	2018-07-12T18:27:19Z						biological_process											owl:Class	
GO:1900722	biolink:NamedThing	regulation of protein adenylylation	Any process that modulates the frequency, rate or extent of protein adenylylation.	got7fsn_ti	regulation of protein amino acid adenylylation|regulation of protein adenylation|regulation of protein AMPylation						jl	2012-05-24T03:15:44Z						biological_process											owl:Class	
GO:1904464	biolink:NamedThing	regulation of matrix metallopeptidase secretion	Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion.	got7fsn_ti	regulation of matrix metalloproteinase secretion|regulation of MMP secretion						sl	2015-07-09T19:46:17Z						biological_process											owl:Class	
PO:0000229	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032724	biolink:NamedThing	positive regulation of fractalkine production	Any process that activates or increases the frequency, rate, or extent of fractalkine production.	got7fsn_ti	up regulation of fractalkine production|activation of fractalkine production|stimulation of fractalkine production|up-regulation of fractalkine production|upregulation of fractalkine production													biological_process											owl:Class	
GO:0036493	biolink:NamedThing	positive regulation of translation in response to endoplasmic reticulum stress	Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.	got7fsn_ti	positive regulation of translation in response to ER stress						bf	2015-02-05T10:09:51Z						biological_process											owl:Class	
GO:0045608	biolink:NamedThing	negative regulation of inner ear auditory receptor cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.	got7fsn_ti	negative regulation of auditory hair cell differentiation|downregulation of auditory receptor cell differentiation|negative regulation of auditory receptor cell differentiation|inhibition of auditory receptor cell differentiation|down regulation of auditory receptor cell differentiation|down-regulation of auditory receptor cell differentiation													biological_process											owl:Class	
GO:0034239	biolink:NamedThing	regulation of macrophage fusion	Any process that modulates the frequency, rate or extent of macrophage fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0001309	biolink:NamedThing	obsolete age-dependent telomere shortening	OBSOLETE. Progressive reduction in length of the telomeres, the termini of eukaryotic chromosomes, that occurs as part of the cellular aging process.	got7fsn_ti	age-dependent telomere shortening				This term was made obsolete because it represents a phenotype.	GO:1903824				True				biological_process											owl:Class	
GO:1904123	biolink:NamedThing	positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway	A serotonin receptor signaling pathway that results in positive regulation of fatty acid beta-oxidation.	got7fsn_ti	up-regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|stimulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|upregulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|up regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|activation of fatty acid beta-oxidation by serotonin receptor signaling pathway						kmv	2015-04-08T21:03:20Z						biological_process											owl:Class	
GO:1904854	biolink:NamedThing	proteasome core complex binding	Binding to a proteasome core complex.	got7fsn_ti	20S core complex binding|macropain binding|PA28gamma-20S proteasome binding|20S proteasome binding						mah	2015-12-15T11:54:19Z						molecular_function											owl:Class	
GO:0003803	biolink:NamedThing	obsolete coagulation factor IXa activity	OBSOLETE. Catalysis of the selective cleavage of the Arg-Ile bond in factor X to form factor Xa.	got7fsn_ti	coagulation factor IXa activity|Christmas factor activity|blood platelet cofactor II|blood coagulation factor IX activity|activated christmas factor|blood-coagulation factor IXa|activated blood coagulation factor XI|autoprothrombin II|activated blood-coagulation factor IX			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0005070	biolink:NamedThing	obsolete SH3/SH2 adaptor activity	OBSOLETE. Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).	got7fsn_ti	SH3/SH2 adaptor protein activity				This term was obsoleted because molecular adaptors should be represented by the type of molecules they serve to adapt, and not by their domains.					True				molecular_function											owl:Class	
GO:0044128	biolink:NamedThing	obsolete positive regulation of growth of symbiont in host	OBSOLETE. Any process in which the symbiont activates, maintains or increases its size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T02:20:57Z		True				biological_process											owl:Class	
GO:1905875	biolink:NamedThing	negative regulation of postsynaptic density organization	Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization.	got7fsn_ti	down-regulation of postsynaptic density organisation|down-regulation of post synaptic density organization|down regulation of post synaptic density organization|negative regulation of postsynaptic density organisation|down-regulation of postsynaptic density organization|down-regulation of post-synaptic density organization|downregulation of post synaptic density organization|down regulation of PSD organization|inhibition of postsynaptic density organisation|downregulation of PSD organization|negative regulation of post synaptic density organization|inhibition of postsynaptic density organization|negative regulation of PSD organization|negative regulation of post-synaptic density organization|inhibition of post-synaptic density organization|down regulation of postsynaptic density organization|downregulation of post-synaptic density organization|down-regulation of PSD organization|inhibition of post synaptic density organization|downregulation of postsynaptic density organization|down regulation of post-synaptic density organization|inhibition of PSD organization|downregulation of postsynaptic density organisation|down regulation of postsynaptic density organisation						sl	2017-01-27T19:53:41Z						biological_process											owl:Class	
GO:2001069	biolink:NamedThing	glycogen binding	Binding to glycogen.	got7fsn_ti	animal starch binding|liver starch binding						jl	2011-09-14T12:01:06Z						molecular_function											owl:Class	
GO:1904493	biolink:NamedThing	tetrahydrofolyl-poly(glutamate) polymer binding	Binding to tetrahydrofolyl-poly(glutamate) polymer.	got7fsn_ti							hal	2015-07-20T10:34:28Z						molecular_function											owl:Class	
GO:1903650	biolink:NamedThing	negative regulation of cytoplasmic transport	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.	got7fsn_ti	down-regulation of cytoplasmic streaming|inhibition of cytoplasmic streaming|down regulation of cytoplasmic streaming|negative regulation of cytoplasmic streaming|down regulation of cytoplasmic transport|downregulation of cytoplasmic transport|down-regulation of cytoplasmic transport|inhibition of cytoplasmic transport|downregulation of cytoplasmic streaming						jl	2014-11-24T13:38:26Z						biological_process											owl:Class	
GO:0009693	biolink:NamedThing	ethylene biosynthetic process	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.	got7fsn_ti	ethylene biosynthesis|ethene biosynthetic process|ethylene formation|ethylene synthesis|ethene biosynthesis from L-methionine|ethylene anabolism|ethylene biosynthesis from L-methionine|ethene biosynthesis|ethylene biosynthetic process from L-methionine|ethene biosynthetic process from L-methionine										GO:0042456	MetaCyc:ETHYL-PWY		biological_process											owl:Class	
GO:0005709	biolink:NamedThing	obsolete prophase chromosome	OBSOLETE. A chromosome found in the cell during prophase.	got7fsn_ti	prophase chromosome				This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0005694				True				cellular_component											owl:Class	
GO:0052394	biolink:NamedThing	obsolete induction by organism of defense-related symbiont cell wall thickening	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of symbiont defensive cell wall thickening|induction by organism of defense-related symbiont cell wall thickening|activation by organism of symbiont defense-related cell wall thickening|activation by organism of symbiont defensive cell wall thickening				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0030635	biolink:NamedThing	obsolete acetate derivative metabolic process	OBSOLETE. The chemical reactions and pathways involving derivatives of acetic acid.	got7fsn_ti	acetate derivative metabolic process|acetate derivative metabolism				This term was made obsolete because it is an unnecessary grouping term, and has been replaced by terms to describe metabolism of specific compounds.	GO:1900619				True				biological_process											owl:Class	
GO:1904524	biolink:NamedThing	negative regulation of DNA amplification	Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification.	got7fsn_ti	inhibition of DNA amplification|downregulation of DNA amplification|down regulation of DNA amplification|down-regulation of DNA amplification						mcc	2015-07-29T16:24:19Z						biological_process											owl:Class	
GO:1905531	biolink:NamedThing	positive regulation of uracil import across plasma membrane	Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane.	got7fsn_ti							vw	2016-10-05T21:03:56Z						biological_process											owl:Class	
GO:1905154	biolink:NamedThing	negative regulation of membrane invagination	Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination.	got7fsn_ti	down-regulation of membrane invagination|down regulation of membrane invagination|downregulation of membrane invagination|inhibition of membrane invagination						bf	2016-04-18T15:44:04Z						biological_process											owl:Class	
GO:0046579	biolink:NamedThing	positive regulation of Ras protein signal transduction	Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.	got7fsn_ti	up-regulation of Ras protein signal transduction|stimulation of Ras protein signal transduction|up regulation of Ras protein signal transduction|upregulation of Ras protein signal transduction|activation of Ras protein signal transduction													biological_process											owl:Class	
GO:0010504	biolink:NamedThing	obsolete regulation of cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that modulates the frequency, rate or extent of cell cycle arrest in response to nitrogen starvation.	got7fsn_ti					This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.					True				biological_process											owl:Class	
GO:1900930	biolink:NamedThing	negative regulation of L-tyrosine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell.	got7fsn_ti	downregulation of L-tyrosine uptake|down-regulation of L-tyrosine uptake|inhibition of L-tyrosine uptake|inhibition of L-tyrosine import|down regulation of L-tyrosine uptake|negative regulation of L-tyrosine import|negative regulation of L-tyrosine uptake|down regulation of L-tyrosine import|downregulation of L-tyrosine import|down-regulation of L-tyrosine import						al	2012-06-13T07:43:14Z						biological_process											owl:Class	
UBERON:0003889	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003377	biolink:NamedThing	obsolete regulation of apoptosis by sphingosine-1-phosphate signaling pathway	OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of apoptosis.	got7fsn_ti	regulation of apoptosis by sphingolipid signalling pathway|regulation of apoptosis by sphingolipid signaling pathway				The reason for obsoletion is that this term represents a GO-CAM model.		dph	2009-12-09T06:32:22Z		True				biological_process											owl:Class	
GO:0046894	biolink:NamedThing	obsolete enzyme active site formation via S-amidino-L-cysteine	OBSOLETE. Active site formation via the transient amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:9148748.	GO:0015068				True				biological_process											owl:Class	
GO:0070906	biolink:NamedThing	aspartate:alanine antiporter activity	Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out).	got7fsn_ti	aspartate/alanine antiporter activity|aspartate-alanine antiporter activity						mah	2009-09-04T03:44:15Z				RHEA:33139		molecular_function											owl:Class	
GO:1900451	biolink:NamedThing	positive regulation of glutamate receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway.	got7fsn_ti	up regulation of glutamate signaling pathway|upregulation of glutamate receptor signaling pathway|up-regulation of glutamate signaling pathway|activation of glutamate signaling pathway|positive regulation of glutamate signaling pathway|positive regulation of glutamate signalling pathway|upregulation of glutamate signalling pathway|upregulation of glutamate signaling pathway|activation of glutamate signalling pathway|up-regulation of glutamate receptor signaling pathway|up regulation of glutamate signalling pathway|up-regulation of glutamate signalling pathway|up regulation of glutamate receptor signaling pathway|activation of glutamate receptor signaling pathway						rl	2012-04-27T03:46:03Z						biological_process											owl:Class	
GO:0055025	biolink:NamedThing	positive regulation of cardiac muscle tissue development	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development.	got7fsn_ti	upregulation of cardiac muscle development|stimulation of cardiac muscle development|up-regulation of cardiac muscle development|activation of cardiac muscle development|positive regulation of heart muscle development|up regulation of cardiac muscle development													biological_process											owl:Class	
GO:0045783	biolink:NamedThing	obsolete negative regulation of calcium in ER	OBSOLETE. Any process that reduces the concentration of calcium in the ER.	got7fsn_ti	negative regulation of calcium in ER				This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport').	GO:0006874|GO:0005783				True				biological_process											owl:Class	
GO:0098812	biolink:NamedThing	nuclear rRNA polyadenylation involved in polyadenylation-dependent rRNA catabolic process	The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a rRNA, occurring as part of the process of polyadenylation-dependent rRNA catabolism in the nucleus.	got7fsn_ti	nuclear rRNA polyadenylation involved in poly(A)-dependent rRNA catabolic process|nuclear rRNA polyadenylation during polyadenylation-dependent rRNA catabolic process													biological_process											owl:Class	
GO:0052033	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response	OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	PAMP dependent activation of host innate immunity|MAMP dependent induction of host innate immunity|general elicitor-dependent induction of host innate immunity|pathogen-associated molecular pattern dependent activation by organism of host innate immunity|PTI|general elicitor-dependent activation of host innate immunity|MAMP dependent activation of host innate immunity|pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity|pattern-triggered immunity|PAMP dependent induction of host innate immunity				This term was obsoleted because it has been misused.	GO:0002752|GO:0052034|GO:0002221				True				biological_process											owl:Class	
GO:0005376	biolink:NamedThing	obsolete plasma membrane copper transporter	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	plasma membrane copper transporter				This term was made obsolete because it contains both component and function information.	GO:0005886|GO:0005375				True				molecular_function											owl:Class	
GO:0071386	biolink:NamedThing	cellular response to corticosterone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.	got7fsn_ti							mah	2009-12-11T03:57:44Z						biological_process											owl:Class	
GO:0010714	biolink:NamedThing	positive regulation of collagen metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	got7fsn_ti	positive regulation of collagen metabolism													biological_process											owl:Class	
GO:0044674	biolink:NamedThing	methyl coenzyme M reductase complex	A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis.	got7fsn_ti							jl	2012-08-09T10:52:33Z						cellular_component											owl:Class	
GO:0055089	biolink:NamedThing	fatty acid homeostasis	Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0019562	biolink:NamedThing	obsolete L-phenylalanine catabolic process to phosphoenolpyruvate	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-phenylalanine into other compounds, including phosphoenolpyruvate.	got7fsn_ti	phenylalanine breakdown to phosphoenolpyruvate|phenylalanine degradation to phosphoenolpyruvate				The reason for obsoletion is that there is no evidence that this is a real process.					True		MetaCyc:PHENYLALANINE-DEG1-PWY		biological_process											owl:Class	
GO:0042547	biolink:NamedThing	cell wall modification involved in multidimensional cell growth	The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth.	got7fsn_ti	cell wall modification during multidimensional cell growth|cell wall modification during cell expansion													biological_process											owl:Class	
OBO:OBA_0000046	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005297	biolink:NamedThing	proline:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in).	got7fsn_ti	hydrogen/proline transporter													molecular_function											owl:Class	
GO:0075277	biolink:NamedThing	positive regulation of telium development	Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0018300	biolink:NamedThing	obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide	OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide.	got7fsn_ti	iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide|iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl hexairon hexasulphide				This term was made obsolete because the prismane 6Fe-6S cluster is now thought not to exist.	GO:0018198|GO:0018283				True				biological_process											owl:Class	
GO:1903925	biolink:NamedThing	response to bisphenol A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.	got7fsn_ti							sl	2015-02-11T00:16:46Z						biological_process											owl:Class	
GO:0046250	biolink:NamedThing	limonene biosynthetic process	The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.	got7fsn_ti	limonene biosynthesis|limonene synthesis|limonene formation|limonene anabolism													biological_process											owl:Class	
GO:0075020	biolink:NamedThing	obsolete calcium or calmodulin-mediated activation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont calcium or calmodulin-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	Ca++ or calmodulin-mediated activation of appressorium formation|Ca2+ or calmodulin-mediated activation of appressorium formation				This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1902921	biolink:NamedThing	poly(hydroxyvalerate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate).	got7fsn_ti	poly(hydroxyvalerate) formation|poly(hydroxyvalerate) synthesis|poly(hydroxyvalerate) anabolism|poly(hydroxyvalerate) biosynthesis						tt	2014-04-21T19:12:38Z						biological_process											owl:Class	
GO:0005678	biolink:NamedThing	obsolete chromatin assembly complex	OBSOLETE. Any protein complex that acts in the formation of nucleosomes or higher order chromatin structure.	got7fsn_ti	nucleosome assembly complex|chromatin assembly complex				This term was made obsolete because its definition no longer reflects and cannot be modified to be consistent with the current state of knowledge.	GO:0031497				True				cellular_component											owl:Class	
GO:0045802	biolink:NamedThing	obsolete negative regulation of cytoskeleton	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton.	got7fsn_ti	negative regulation of cytoskeleton				This term was made obsolete because cytoskeleton is not a process, so the term made no sense.	GO:0007010				True				biological_process											owl:Class	
GO:0015363	biolink:NamedThing	obsolete dicarboxylate (succinate/fumarate/malate) antiporter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dicarboxylate (succinate/fumarate/malate) antiporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0005310|GO:0015138|GO:0015297|GO:0015141|GO:0015140				True				molecular_function											owl:Class	
GO:0008729	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:8707	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030005	biolink:NamedThing	obsolete cellular di-, tri-valent inorganic cation homeostasis	OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations at the level of a cell.	got7fsn_ti	cellular di-, tri-valent inorganic cation homeostasis					GO:0072504|GO:0072503				True				biological_process											owl:Class	
CL:1000488	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051423	biolink:NamedThing	positive regulation of endo-1,4-beta-xylanase activity	Any process that activates or increases the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.	got7fsn_ti	activation of endo-1,4-beta-xylanase activity|stimulation of endo-1,4-beta-xylanase activity|up-regulation of endo-1,4-beta-xylanase activity|xylanase activator|up regulation of endo-1,4-beta-xylanase activity|upregulation of endo-1,4-beta-xylanase activity|endo-1,4-beta-xylanase activator													biological_process											owl:Class	
GO:0090412	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process	OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process.	got7fsn_ti	positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process					GO:0045944	tb	2011-09-01T03:10:41Z		True				biological_process											owl:Class	
GO:1902752	biolink:NamedThing	regulation of renal amino acid absorption	Any process that modulates the frequency, rate or extent of renal amino acid absorption.	got7fsn_ti							hjd	2014-03-05T15:43:55Z						biological_process											owl:Class	
GO:0008651	biolink:NamedThing	obsolete actin polymerizing activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	actin polymerizing activity				This term was made obsolete because it represents a biological process.	GO:0030041|GO:0042802				True				molecular_function											owl:Class	
GO:0046587	biolink:NamedThing	positive regulation of calcium-dependent cell-cell adhesion	Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion.	got7fsn_ti	stimulation of calcium-dependent cell-cell adhesion|up-regulation of calcium-dependent cell-cell adhesion|up regulation of calcium-dependent cell-cell adhesion|activation of calcium-dependent cell-cell adhesion|upregulation of calcium-dependent cell-cell adhesion													biological_process											owl:Class	
GO:0051407	biolink:NamedThing	glycerone phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out).	got7fsn_ti	dihydroxyacetone-phosphate:inorganic phosphate antiporter activity													molecular_function											owl:Class	
GO:0010932	biolink:NamedThing	regulation of macrophage tolerance induction	Any process that modulates the frequency, rate, or extent of macrophage tolerance induction.	got7fsn_ti														biological_process											owl:Class	
GO:1902732	biolink:NamedThing	positive regulation of chondrocyte proliferation	Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti	up-regulation of chondrocyte cell proliferation|activation of cartilage cell proliferation|upregulation of chondrocyte cell proliferation|positive regulation of cartilage cell proliferation|upregulation of chondrocyte proliferation|activation of chondrocyte cell proliferation|up regulation of cartilage cell proliferation|upregulation of cartilage cell proliferation|up-regulation of chondrocyte proliferation|up regulation of chondrocyte proliferation|up-regulation of cartilage cell proliferation|positive regulation of chondrocyte cell proliferation|up regulation of chondrocyte cell proliferation|activation of chondrocyte proliferation						mr	2014-02-24T16:11:18Z						biological_process											owl:Class	
GO:0031404	biolink:NamedThing	chloride ion binding	Binding to a chloride ion (Cl-).	got7fsn_ti	Cl- ion binding|chloride binding													molecular_function											owl:Class	
GO:0033147	biolink:NamedThing	negative regulation of intracellular estrogen receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.	got7fsn_ti	negative regulation of estrogen receptor signaling pathway|negative regulation of estrogen receptor signalling pathway													biological_process											owl:Class	
GO:0072706	biolink:NamedThing	response to sodium dodecyl sulfate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.	got7fsn_ti	response to SDS						mah	2012-04-11T03:35:07Z						biological_process											owl:Class	
GO:1902754	biolink:NamedThing	positive regulation of renal amino acid absorption	Any process that activates or increases the frequency, rate or extent of renal amino acid absorption.	got7fsn_ti	up-regulation of renal amino acid absorption|up regulation of renal amino acid absorption|activation of renal amino acid absorption|upregulation of renal amino acid absorption						hjd	2014-03-05T15:44:07Z						biological_process											owl:Class	
GO:0106194	biolink:NamedThing	obsolete translocase activity acting on inorganic cations and their chelates linked to a decarboxylation reaction	OBSOLETE. Catalysis of the transocation of inorganic cations and their chelates linked to a decarboxylation reaction.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T16:58:50Z		True		EC:7.2.4.-		molecular_function											owl:Class	
CHEBI:16347	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001311	biolink:NamedThing	lysobisphosphatidic acid metabolic process	The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.	got7fsn_ti	bis(monoacylglycerol) hydrogen phosphate metabolic process|lysobisphosphatidic acid metabolism|LBPA metabolism|bis(monoacylglycerol) hydrogen phosphate (BMP) metabolism|bis(monoacylglycerol) hydrogen phosphate metabolism|LBPA metabolic process|bis(monoacylglycerol) hydrogen phosphate (BMP) metabolic process						bf	2012-03-16T09:31:27Z						biological_process											owl:Class	
GO:0019292	biolink:NamedThing	tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate	The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate.	got7fsn_ti	tyrosine biosynthetic process from chorismate via p-hydroxyphenylpyruvate|tyrosine anabolism from chorismate via 4-hydroxyphenylpyruvate|tyrosine formation from chorismate via 4-hydroxyphenylpyruvate|tyrosine synthesis from chorismate via 4-hydroxyphenylpyruvate											MetaCyc:TYRSYN		biological_process											owl:Class	
GO:0019609	biolink:NamedThing	3-hydroxyphenylacetate metabolic process	The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.	got7fsn_ti	3HPA metabolic process|3-hydroxyphenylacetate metabolism|3HPA metabolism													biological_process											owl:Class	
GO:0048303	biolink:NamedThing	negative regulation of isotype switching to IgG isotypes	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes.	got7fsn_ti	negative regulation of isotype switch recombination to IgG isotypes|down regulation of isotype switching to IgG isotypes|down-regulation of isotype switching to IgG isotypes|negative regulation of class switching to IgG isotypes|negative regulation of class switch recombination to IgG isotypes|inhibition of isotype switching to IgG isotypes|downregulation of isotype switching to IgG isotypes													biological_process											owl:Class	
GO:1903705	biolink:NamedThing	positive regulation of production of siRNA involved in RNA interference	Any process that activates or increases the frequency, rate or extent of production of siRNA involved in RNA interference.	got7fsn_ti	activation of RNA interference, production of guide RNAs|up regulation of RNA interference, production of guide RNAs|upregulation of production of siRNA involved in RNA interference|activation of production of siRNA involved in RNA interference|upregulation of production of guide RNAs involved in RNA interference|up-regulation of RNA interference, production of siRNA|activation of RNA interference, production of siRNA|upregulation of RNA interference, production of guide RNAs|up regulation of production of guide RNAs involved in RNA interference|upregulation of RNA interference, production of siRNA|up-regulation of production of guide RNAs involved in RNA interference|up-regulation of production of siRNA involved in RNA interference|activation of production of guide RNAs involved in RNA interference|up regulation of production of siRNA involved in RNA interference|positive regulation of production of guide RNAs involved in RNA interference|up regulation of RNA interference, production of siRNA|positive regulation of RNA interference, production of siRNA|positive regulation of RNA interference, production of guide RNAs|up-regulation of RNA interference, production of guide RNAs						nc	2014-12-03T15:13:30Z						biological_process											owl:Class	
GO:0046645	biolink:NamedThing	positive regulation of gamma-delta T cell activation	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation.	got7fsn_ti	activation of gamma-delta T cell activation|up regulation of gamma-delta T cell activation|up-regulation of gamma-delta T cell activation|positive regulation of gamma-delta T lymphocyte activation|positive regulation of gamma-delta T-cell activation|upregulation of gamma-delta T cell activation|positive regulation of gamma-delta T-lymphocyte activation|stimulation of gamma-delta T cell activation													biological_process											owl:Class	
GO:0008350	biolink:NamedThing	obsolete kinetochore motor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	kinetochore motor activity				This term was made obsolete because it includes cellular component information.	GO:0003777|GO:0000776				True				molecular_function											owl:Class	
GO:1990371	biolink:NamedThing	obsolete process resulting in tolerance to phenol	OBSOLETE. A response that results in a state of tolerance to phenol.	got7fsn_ti					This term was obsoleted because it does not represent a clear process.		tt	2014-04-23T22:32:48Z		True				biological_process											owl:Class	
GO:1901025	biolink:NamedThing	ripoptosome assembly involved in extrinsic apoptotic signaling pathway	The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway.	got7fsn_ti							pr	2012-06-19T08:49:33Z						biological_process											owl:Class	
GO:0046439	biolink:NamedThing	L-cysteine metabolic process	The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.	got7fsn_ti	L-cysteine metabolism													biological_process											owl:Class	
GO:0000044	biolink:NamedThing	obsolete ascorbate stabilization	OBSOLETE. The reduction of the ascorbate free radical to a stable form.	got7fsn_ti	vitamin C stabilization|ascorbate stabilization				This term was made obsolete because it is defined as a function term and is in the process ontology.					True				biological_process											owl:Class	
GO:1903372	biolink:NamedThing	negative regulation of endoplasmic reticulum tubular network organization	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization.	got7fsn_ti	inhibition of endoplasmic reticulum tubular network organisation|down-regulation of ER tubular network organisation|down regulation of ER tubular network organisation|down regulation of endoplasmic reticulum tubular network organization|downregulation of endoplasmic reticulum tubular network organization|downregulation of endoplasmic reticulum tubular network organisation|inhibition of ER tubular network organisation|down regulation of endoplasmic reticulum tubular network organisation|negative regulation of ER tubular network organization|down-regulation of ER tubular network organization|downregulation of ER tubular network organisation|down regulation of ER tubular network organization|inhibition of ER tubular network organization|downregulation of ER tubular network organization|down-regulation of endoplasmic reticulum tubular network organization|inhibition of endoplasmic reticulum tubular network organization|negative regulation of endoplasmic reticulum tubular network organisation|negative regulation of ER tubular network organisation|down-regulation of endoplasmic reticulum tubular network organisation						als	2014-08-22T11:01:23Z						biological_process											owl:Class	
GO:0031457	biolink:NamedThing	glycine betaine catabolic process	The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.	got7fsn_ti	N-trimethylglycine catabolic process|glycine betaine breakdown|glycine betaine degradation|N-trimethylglycine catabolism|glycine betaine catabolism													biological_process											owl:Class	
GO:0044408	biolink:NamedThing	obsolete growth or development of symbiont on or near host	OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism.	got7fsn_ti	growth or development of organism on or near host surface|growth or development of symbiont on or near host									True				biological_process											owl:Class	
GO:1901373	biolink:NamedThing	lipid hydroperoxide transport	The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2012-09-28T00:24:39Z						biological_process											owl:Class	
GO:0033630	biolink:NamedThing	positive regulation of cell adhesion mediated by integrin	Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.	got7fsn_ti	positive regulation of cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0098639	biolink:NamedThing	collagen binding involved in cell-matrix adhesion	Any collagen binding that occurs as part of cell-matrix adhesion.	got7fsn_ti														molecular_function											owl:Class	
GO:0032016	biolink:NamedThing	negative regulation of Ran protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction.	got7fsn_ti	down regulation of Ran protein signal transduction|inhibition of Ran protein signal transduction|down-regulation of Ran protein signal transduction|downregulation of Ran protein signal transduction													biological_process											owl:Class	
GO:0032847	biolink:NamedThing	regulation of cellular pH reduction	Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell.	got7fsn_ti	regulation of intracellular pH reduction|regulation of intracellular acidification|regulation of reduction of pH in cell|regulation of cellular acidification|regulation of cell pH reduction|regulation of reduction of cellular pH													biological_process											owl:Class	
GO:0046118	biolink:NamedThing	7-methylguanosine biosynthetic process	The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.	got7fsn_ti	7-methylguanosine synthesis|7-methylguanosine biosynthesis|7-methylguanosine formation|7-methylguanosine anabolism													biological_process											owl:Class	
GO:0045636	biolink:NamedThing	positive regulation of melanocyte differentiation	Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.	got7fsn_ti	up regulation of melanocyte differentiation|up-regulation of melanocyte differentiation|stimulation of melanocyte differentiation|activation of melanocyte differentiation|positive regulation of melanophore differentiation|upregulation of melanocyte differentiation													biological_process											owl:Class	
GO:0004231	biolink:NamedThing	obsolete insulysin activity	OBSOLETE. Catalysis of the degradation of insulin, glucagon and other polypeptides. No action on proteins.	got7fsn_ti	insulin-degrading neutral proteinase activity|insulinase activity|insulysin activity|insulin proteinase activity|insulin-degrading enzyme activity|insulin-specific protease activity|insulin-glucagon protease activity|insulin protease activity|IDE|metalloinsulinase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1903136	biolink:NamedThing	cuprous ion binding	Binding to a cuprous ion, copper(1+).	got7fsn_ti	copper(1+) binding|Cu(I) binding|Cu(+) binding						bf	2014-06-26T14:38:23Z						molecular_function											owl:Class	
GO:0001629	biolink:NamedThing	obsolete G-protein receptor 45-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	G protein receptor 45-like receptor activity|GPR45-like receptor|G-protein receptor 45-like receptor activity				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True				molecular_function											owl:Class	
GO:0034127	biolink:NamedThing	regulation of MyD88-independent toll-like receptor signaling pathway	Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.	got7fsn_ti	regulation ofMyD88-independent toll-like receptor signalling pathway|regulation ofMyD88-independent TLR signaling pathway													biological_process											owl:Class	
GO:1900093	biolink:NamedThing	positive regulation of raffinose biosynthetic process	Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process.	got7fsn_ti	up regulation of raffinose anabolism|up regulation of raffinose formation|up-regulation of raffinose biosynthetic process|upregulation of raffinose biosynthetic process|activation of raffinose formation|up-regulation of raffinose formation|activation of raffinose biosynthetic process|upregulation of raffinose synthesis|positive regulation of raffinose biosynthesis|activation of raffinose anabolism|upregulation of raffinose formation|activation of raffinose synthesis|positive regulation of raffinose synthesis|positive regulation of raffinose anabolism|up-regulation of raffinose synthesis|activation of raffinose biosynthesis|up-regulation of raffinose biosynthesis|upregulation of raffinose anabolism|up regulation of raffinose biosynthetic process|positive regulation of raffinose formation|up-regulation of raffinose anabolism|upregulation of raffinose biosynthesis|up regulation of raffinose biosynthesis|up regulation of raffinose synthesis						dhl	2012-02-08T06:32:01Z						biological_process											owl:Class	
GO:0039550	biolink:NamedThing	obsolete suppression by virus of host IRF3 activity by inhibition of DNA binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF3-dependent gene transcription, by preventing or reducing IRF3 binding to promoter sites.	got7fsn_ti	inhibition by virus of host IRF3-DNA binding				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-19T04:27:25Z		True				biological_process											owl:Class	
GO:0018323	biolink:NamedThing	obsolete enzyme active site formation via L-cysteine sulfinic acid	OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfinic acid.	got7fsn_ti	enzyme active site formation via L-cysteine sulphinic acid	https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:9586994.	GO:0018822				True		RESID:AA0262		biological_process											owl:Class	
GO:0039603	biolink:NamedThing	obsolete TBP-class protein binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter	OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the class of TATA-binding proteins (TBP) in the host, including any of the TBP-related factors (TRFs), which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14640			The reason for obsoletion is that the term is too specific, and the paper referenced in the term should instead be annotated to GO:0039602 ; suppression by virus of host transcription initiation from RNA polymerase II promoter.		bf	2012-07-05T04:00:15Z		True				molecular_function											owl:Class	
GO:0006015	biolink:NamedThing	5-phosphoribose 1-diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.	got7fsn_ti	5-phosphoribosyl-1-pyrophosphate biosynthetic process|PRPP biosynthetic process|5-phosphoribose 1-diphosphate biosynthesis|5-phosphoribose 1-diphosphate formation|5-phosphoribosyl-1-pyrophosphate biosynthesis|5-phosphoribose 1-diphosphate anabolism|5-phosphoribose 1-diphosphate synthesis											MetaCyc:PWY0-661		biological_process											owl:Class	
GO:0031563	biolink:NamedThing	mating projection tip polarisome	Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.	got7fsn_ti														cellular_component											owl:Class	
GO:1904769	biolink:NamedThing	isopentadecanoic acid binding	Binding to isopentadecanoic acid.	got7fsn_ti	13-methylmyristic acid binding						kmv	2015-10-27T21:33:38Z						molecular_function											owl:Class	
GO:1900940	biolink:NamedThing	positive regulation of (Z)-nonadeca-1,14-diene metabolic process	Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.	got7fsn_ti	upregulation of (Z)-nonadeca-1,14-diene metabolic process|positive regulation of (Z)-nonadeca-1,14-diene metabolism|up regulation of (Z)-nonadeca-1,14-diene metabolism|upregulation of (Z)-nonadeca-1,14-diene metabolism|activation of (Z)-nonadeca-1,14-diene metabolism|up regulation of (Z)-nonadeca-1,14-diene metabolic process|activation of (Z)-nonadeca-1,14-diene metabolic process|up-regulation of (Z)-nonadeca-1,14-diene metabolism|up-regulation of (Z)-nonadeca-1,14-diene metabolic process						tt	2012-06-14T03:16:05Z						biological_process											owl:Class	
GO:0006210	biolink:NamedThing	thymine catabolic process	The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.	got7fsn_ti	thymine breakdown|thymine degradation|thymine catabolism													biological_process											owl:Class	
GO:0005557	biolink:NamedThing	obsolete lymphocyte antigen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lymphocyte antigen				This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True				molecular_function											owl:Class	
GO:1903625	biolink:NamedThing	negative regulation of DNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.	got7fsn_ti	downregulation of DNA catabolic process|down-regulation of DNA breakdown|inhibition of DNA degradation|down-regulation of DNA catabolism|inhibition of DNA breakdown|negative regulation of DNA catabolism|down-regulation of DNA catabolic process|downregulation of DNA breakdown|inhibition of DNA catabolic process|down regulation of DNA catabolism|negative regulation of DNA degradation|down regulation of DNA catabolic process|down regulation of DNA breakdown|downregulation of DNA degradation|downregulation of DNA catabolism|down regulation of DNA degradation|negative regulation of DNA breakdown|inhibition of DNA catabolism|down-regulation of DNA degradation						sl	2014-11-19T22:36:43Z						biological_process											owl:Class	
GO:0001074	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly	OBSOLETE. Binding to a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter.	got7fsn_ti	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly	https://github.com/geneontology/go-ontology/issues/16554			This term has been obsoleted because it represents a GO-CAM model.		krc	2010-10-22T02:30:43Z		True				molecular_function											owl:Class	
GO:0048359	biolink:NamedThing	mucilage metabolic process involved in seed coat development	The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.	got7fsn_ti	mucilage metabolism during seed coat development|mucilage metabolic process during seed coat development													biological_process											owl:Class	
GO:0085010	biolink:NamedThing	obsolete interaction with host mediated by secreted substance entering host via endocytosis	OBSOLETE. An interaction with the host organism mediated by a secreted substance from the symbiont entering host cells via endocytosis of the substance. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:12:31Z		True				biological_process											owl:Class	
GO:0004221	biolink:NamedThing	obsolete ubiquitin thiolesterase activity	OBSOLETE. Catalysis of the reaction: ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol.	got7fsn_ti	ubiquitin thiolesterase activity|ubiquitin carboxy-terminal esterase activity|ubiquitin thioesterase activity|ubiquitin C-terminal hydrolase activity|ubiquitinyl hydrolase 1 activity|ubiquitin-C-terminal-thioester hydrolase activity|ubiquitin carboxy-terminal hydrolase activity				This term was made obsolete because this molecular function does not exist.	GO:0004843				True	GO:0008577	KEGG_REACTION:R02418|MetaCyc:UBIQUITIN-THIOLESTERASE-RXN		molecular_function											owl:Class	
GO:1990815	biolink:NamedThing	obsolete regulation of protein localization to cell division site after cytokinesis	OBSOLETE. Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in cell separation after cytokinesis.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2015-07-29T14:03:34Z		True				biological_process											owl:Class	
CHEBI:9937	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000993	biolink:NamedThing	positive regulation of galactomannan catabolic process	Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process.	got7fsn_ti							tt	2011-08-08T03:16:07Z						biological_process											owl:Class	
GO:1904916	biolink:NamedThing	transmembrane L-lysine transport from lysosomal lumen to cytosol	The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol.	got7fsn_ti							kmv	2016-01-21T16:27:41Z						biological_process											owl:Class	
GO:0034757	biolink:NamedThing	negative regulation of iron ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	downregulation of iron ion transport|down-regulation of iron ion transport|down regulation of iron ion transport|inhibition of iron ion transport|negative regulation of iron transport													biological_process											owl:Class	
GO:0007357	biolink:NamedThing	obsolete positive regulation of central gap gene transcription	OBSOLETE. The activation of genes encoding transcription factors in the central region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila Kruppel gene by the hunchback and bicoid gene products.	got7fsn_ti	activation of central gap gene transcription|up-regulation of central gap gene transcription|up regulation of central gap gene transcription|activation of central gap gene|upregulation of central gap gene transcription|stimulation of central gap gene transcription				This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1900987	biolink:NamedThing	ajmaline catabolic process	The chemical reactions and pathways resulting in the breakdown of ajmaline.	got7fsn_ti	ajmaline breakdown|ajmaline degradation|ajmaline catabolism						yaf	2012-06-14T09:47:26Z						biological_process											owl:Class	
GO:0006254	biolink:NamedThing	CTP catabolic process	The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate.	got7fsn_ti	CTP hydrolysis|CTP catabolism|CTP breakdown|CTP degradation													biological_process											owl:Class	
GO:0106011	biolink:NamedThing	regulation of protein localization to medial cortex	Any process that regulates the localization of a protein to the medial cortex.	got7fsn_ti							hjd	2017-04-27T17:29:56Z						biological_process											owl:Class	
GO:0043946	biolink:NamedThing	obsolete positive regulation of catalytic activity in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	activation of enzyme activity in other organism during symbiotic interaction|positive regulation of catalytic activity in other organism during symbiotic interaction|activation of enzyme activity in other organism|upregulation of enzyme activity in other organism during symbiotic interaction|up-regulation of enzyme activity in other organism during symbiotic interaction|up regulation of enzyme activity in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.	GO:0140677				True				biological_process											owl:Class	
GO:1990978	biolink:NamedThing	obsolete response to viscosity	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-08-17T20:10:36Z		True				biological_process											owl:Class	
GO:1904872	biolink:NamedThing	regulation of telomerase RNA localization to Cajal body	Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body.	got7fsn_ti							nc	2015-12-18T11:28:20Z						biological_process											owl:Class	
GO:0046636	biolink:NamedThing	negative regulation of alpha-beta T cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation.	got7fsn_ti	downregulation of alpha-beta T cell activation|down-regulation of alpha-beta T cell activation|negative regulation of alpha-beta T lymphocyte activation|inhibition of alpha-beta T cell activation|negative regulation of alpha-beta T-lymphocyte activation|negative regulation of alpha-beta T-cell activation|down regulation of alpha-beta T cell activation													biological_process											owl:Class	
PR:000016156	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900678	biolink:NamedThing	regulation of ferricrocin biosynthetic process	Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process.	got7fsn_ti	regulation of ferricrocin biosynthetic process, peptide formation|regulation of ferricrocin anabolism|regulation of ferricrocin synthesis|regulation of ferricrocin formation|regulation of ferricrocin biosynthesis|regulation of ferricrocin biosynthetic process, peptide modification						di	2012-05-22T04:27:53Z						biological_process											owl:Class	
GO:0100040	biolink:NamedThing	obsolete negative regulation of invasive growth in response to glucose limitation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates invasive growth in response to glucose limitation.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0001063	biolink:NamedThing	obsolete plastid PEP-B RNA polymerase activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-B RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16738		GO:0003899	This term was obsoleted because the activity is the same as its parent.		krc	2010-10-19T03:46:46Z		True				molecular_function											owl:Class	
GO:1905514	biolink:NamedThing	positive regulation of short-term synaptic potentiation	Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation.	got7fsn_ti	upregulation of synaptic facilitation|up regulation of synaptic facilitation|upregulation of short-term synaptic potentiation|up regulation of short-term synaptic potentiation|positive regulation of synaptic facilitation|up-regulation of short-term synaptic potentiation|up-regulation of synaptic facilitation|activation of synaptic facilitation|activation of short-term synaptic potentiation						hjd	2016-09-28T17:40:30Z						biological_process											owl:Class	
GO:0060796	biolink:NamedThing	obsolete regulation of transcription involved in primary germ layer cell fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0060795	dph	2009-08-04T03:40:21Z		True				biological_process											owl:Class	
GO:0002843	biolink:NamedThing	regulation of tolerance induction to tumor cell	Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell.	got7fsn_ti	regulation of tolerance induction to tumour cell													biological_process											owl:Class	
GO:0001902	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0110020	biolink:NamedThing	regulation of actomyosin structure organization	Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.	got7fsn_ti							kmv	2017-06-20T19:28:58Z						biological_process											owl:Class	
GO:0032473	biolink:NamedThing	cytoplasmic side of mitochondrial outer membrane	The external (cytoplasmic) face of the mitochondrial outer membrane.	got7fsn_ti	external side of mitochondrial envelope|external leaflet of mitochondrial outer membrane|cytosolic side of mitochondrial outer membrane|external side of mitochondrial outer membrane				In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane.									cellular_component											owl:Class	
GO:1990348	biolink:NamedThing	obsolete G/A mismatch specific adenine DNA glycosylase activity	OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite guanine in the template by adenine DNA glycosylase activity. The reaction leaves an apurinic AP site. I also requested same term but for Go/A mismatch. If you think it is better to make one term for mismatched adenine that is fine by me.	got7fsn_ti	G/A mismatch specific adenine DNA glycosylase activity				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-03-25T10:55:45Z		True				molecular_function											owl:Class	
GO:0046270	biolink:NamedThing	obsolete 4-toluenecarboxylate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.	got7fsn_ti	4-toluenecarboxylate anabolism|4-toluenecarboxylate synthesis|4-toluenecarboxylate biosynthesis|4-toluenecarboxylate biosynthetic process|4-toluenecarboxylate formation			GO:0019611	This term was made obsolete because 4-toluenecarboxylate is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0051437	biolink:NamedThing	obsolete positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the regulation of the mitotic cell cycle phase transition.	got7fsn_ti	up regulation of ubiquitin ligase activity during mitotic cell cycle|up-regulation of ubiquitin ligase activity during mitotic cell cycle|positive regulation of ubiquitin ligase activity during mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle|mitotic SCF complex activator|mitotic ubiquitin ligase activator|upregulation of ubiquitin ligase activity during mitotic cell cycle|activation of ubiquitin ligase activity during mitotic cell cycle|stimulation of ubiquitin ligase activity during mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/15196			This term was obsoleted because it should be captured as a GO-CAM model.					True				biological_process											owl:Class	
GO:1901722	biolink:NamedThing	regulation of cell proliferation involved in kidney development	Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development.	got7fsn_ti							krc	2012-12-27T19:30:31Z						biological_process											owl:Class	
GO:1903305	biolink:NamedThing	regulation of regulated secretory pathway	Any process that modulates the frequency, rate or extent of regulated secretory pathway.	got7fsn_ti					An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.		pad	2014-08-18T10:04:53Z						biological_process											owl:Class	
GO:2001241	biolink:NamedThing	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.	got7fsn_ti	positive regulation of dependence receptor signaling pathway|positive regulation of extrinsic apoptotic signalling pathway in absence of ligand|positive regulation of extrinsic apoptosis in absence of ligand						pr	2011-11-24T01:33:31Z						biological_process											owl:Class	
GO:0030549	biolink:NamedThing	acetylcholine receptor activator activity	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:57853	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043924	biolink:NamedThing	suramin binding	Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms.	got7fsn_ti	Germanin binding													molecular_function											owl:Class	
GO:1901457	biolink:NamedThing	regulation of response to acetate	Any process that modulates the frequency, rate or extent of response to acetate.	got7fsn_ti							tt	2012-10-02T14:25:06Z						biological_process											owl:Class	
GO:1904159	biolink:NamedThing	megasporocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte.	got7fsn_ti	megaspore mother cell differentiation				The process aimed at the progression of a megasporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A megasporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) megaspores; also called megaspore mother cell.		lr	2015-04-17T20:25:14Z						biological_process											owl:Class	
GO:0031402	biolink:NamedThing	sodium ion binding	Binding to a sodium ion (Na+).	got7fsn_ti	Na+ ion binding													molecular_function											owl:Class	
GO:1901060	biolink:NamedThing	p-hydroxyphenyl lignin biosynthetic process	The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin.	got7fsn_ti	p-hydroxyphenyl lignin synthesis|H-lignin biosynthetic process|p-hydroxyphenyl lignin formation|p-hydroxyphenyl lignin anabolism|p-hydroxyphenyl lignin biosynthesis						tt	2012-06-29T02:42:36Z						biological_process											owl:Class	
UBERON:0000948	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009619	biolink:NamedThing	obsolete resistance to pathogenic bacteria	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	resistance to pathogenic bacteria			GO:0009617	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0097200	biolink:NamedThing	cysteine-type endopeptidase activity involved in execution phase of apoptosis	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.	got7fsn_ti	executioner caspase activity|effector caspase activity				Examples of gene products that may be annotated to this term include CASP3, CASP6 and CASP7, also called effector (or executioner) caspases.		pr	2011-12-12T01:46:06Z						molecular_function											owl:Class	
GO:0033352	biolink:NamedThing	UDP-D-apiose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-D-apiose anabolism|UDP-D-apiose synthesis|UDP-D-apiose formation|UDP-D-apiose biosynthesis											MetaCyc:PWY-4821|MetaCyc:PWY-5113		biological_process											owl:Class	
GO:0004928	biolink:NamedThing	obsolete frizzled receptor activity	OBSOLETE. Combining with a member of the Wnt-family of signaling molecules to initiate a change in cell activity.	got7fsn_ti	frizzled receptor activity			GO:0042813	This term was made obsolete because it represents a gene product rather than an activity.	GO:0016055				True				molecular_function											owl:Class	
GO:0002311	biolink:NamedThing	gamma-delta T cell proliferation involved in immune response	The expansion of a gamma-delta T cell population by cell division as part of an immune response.	got7fsn_ti	gamma-delta T cell proliferation during immune response|gamma-delta T-lymphocyte proliferation during immune response|gamma-delta T-cell proliferation during immune response|gamma-delta T lymphocyte proliferation during immune response													biological_process											owl:Class	
GO:1901523	biolink:NamedThing	icosanoid catabolic process	The chemical reactions and pathways resulting in the breakdown of icosanoid.	got7fsn_ti	icosanoid catabolism|icosanoid degradation|icosanoid breakdown						pr	2012-10-22T10:50:09Z						biological_process											owl:Class	
GO:1900931	biolink:NamedThing	positive regulation of L-tyrosine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell.	got7fsn_ti	positive regulation of L-tyrosine uptake|upregulation of L-tyrosine import|upregulation of L-tyrosine uptake|up regulation of L-tyrosine import|up regulation of L-tyrosine uptake|positive regulation of L-tyrosine import|up-regulation of L-tyrosine uptake|up-regulation of L-tyrosine import|activation of L-tyrosine import|activation of L-tyrosine uptake						al	2012-06-13T07:43:21Z						biological_process											owl:Class	
GO:1905181	biolink:NamedThing	regulation of urease activity	Any process that modulates the frequency, rate or extent of urease activity.	got7fsn_ti	regulation of urea amidohydrolase activity						tb	2016-05-09T23:15:54Z						biological_process											owl:Class	
GO:0140581	biolink:NamedThing	P-type monovalent copper transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) -> ADP + phosphate + Cu+(out).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20699			Note that this enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC:7.2.2.9, which mainly transports the divalent copper ion (source: EC:7.2.2.8).		pg	2021-01-18T11:15:13Z				EC:7.2.2.8|RHEA:25792		molecular_function											owl:Class	
GO:1904671	biolink:NamedThing	negative regulation of cell differentiation involved in stem cell population maintenance	Any negative regulation of cell differentiation that is involved in stem cell population maintenance.	got7fsn_ti	negative regulation of cell differentiation involved in maintenance of pluripotency|inhibition of cell differentiation involved in maintenance of pluripotency|down-regulation of cell differentiation involved in stem cell population maintenance|inhibition of cell differentiation involved in stem cell population maintenance|downregulation of cell differentiation involved in stem cell population maintenance|downregulation of cell differentiation involved in maintenance of pluripotency|down-regulation of cell differentiation involved in maintenance of pluripotency|down regulation of cell differentiation involved in stem cell population maintenance|down regulation of cell differentiation involved in maintenance of pluripotency						tb	2015-09-12T00:46:08Z						biological_process											owl:Class	
GO:0052121	biolink:NamedThing	obsolete positive chemotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive chemotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0030092	biolink:NamedThing	obsolete regulation of flagellum assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of the formation of a flagellum.	got7fsn_ti	regulation of flagella biogenesis|regulation of flagella assembly|regulation of flagellum assembly|regulation of flagellum biogenesis				This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:1902208|GO:1902017				True				biological_process											owl:Class	
GO:1904409	biolink:NamedThing	regulation of secretory granule organization	Any process that modulates the frequency, rate or extent of secretory granule organization.	got7fsn_ti	regulation of secretory granule organization and biogenesis|regulation of secretory granule organisation						sl	2015-06-25T19:40:42Z						biological_process											owl:Class	
CHEBI:64497	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075102	biolink:NamedThing	obsolete negative regulation by host of symbiont MAP kinase-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont MAP kinase-mediated signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:1902708	biolink:NamedThing	response to plumbagin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.	got7fsn_ti							mah	2014-02-20T13:49:54Z						biological_process											owl:Class	
GO:2001077	biolink:NamedThing	(1->3),(1->4)-beta-glucan binding	Binding to (1->3),(1->4)-beta-glucan.	got7fsn_ti	(1,3),(1,4)-beta-glucan binding|beta-1->3,1->4-glucan binding|1->3,1->4-beta-glucan binding|beta-(1,3),(1,4)-glucan binding|beta-1,3-1,4-glucan binding|beta-(1->3),(1->4)-glucan binding						jl	2011-09-15T09:07:33Z						molecular_function											owl:Class	
GO:0140115	biolink:NamedThing	export across plasma membrane	The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	efflux						pg	2017-10-24T14:38:16Z						biological_process											owl:Class	
GO:1905504	biolink:NamedThing	negative regulation of motile cilium assembly	Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly.	got7fsn_ti	down regulation of nodal cilium formation|downregulation of motile primary cilia formation|down-regulation of nodal cilium assembly|down regulation of motile primary cilium assembly|down regulation of motile primary cilia assembly|negative regulation of motile primary cilium formation|down regulation of nodal cilium assembly|downregulation of nodal cilium assembly|inhibition of motile primary cilia formation|negative regulation of nodal cilium assembly|downregulation of motile primary cilia assembly|down-regulation of motile primary cilium formation|down regulation of motile primary cilium formation|down-regulation of nodal cilium formation|inhibition of motile primary cilium formation|downregulation of motile primary cilium assembly|inhibition of motile primary cilia assembly|down-regulation of motile primary cilia formation|negative regulation of motile primary cilia formation|down regulation of motile primary cilia formation|down-regulation of motile primary cilia assembly|inhibition of nodal cilium assembly|inhibition of nodal cilium formation|negative regulation of nodal cilium formation|negative regulation of motile primary cilium assembly|downregulation of nodal cilium formation|negative regulation of motile primary cilia assembly|downregulation of motile primary cilium formation|inhibition of motile primary cilium assembly|down-regulation of motile primary cilium assembly						krc	2016-09-27T18:27:55Z						biological_process											owl:Class	
GO:1902703	biolink:NamedThing	hexose catabolic process to butan-1-ol	The chemical reactions and pathways resulting in the breakdown of hexose to butan-1-ol.	got7fsn_ti	hexose catabolic process to 1-butanol|solventogenesis|hexose breakdown to butan-1-ol|hexose degradation to butan-1-ol|hexose catabolism to butan-1-ol|hexose catabolic process to butanol						tb	2014-02-19T18:43:04Z			GO:1990284			biological_process											owl:Class	
GO:1902483	biolink:NamedThing	cytotoxic T cell pyroptotic process	Any pyroptotic process in a cytotoxic T cell.	got7fsn_ti	cytotoxic T cell apoptotic process|cytotoxic T cell apoptosis|cytotoxic T-cell apoptotic process|cytotoxic T-cell apoptosis|cytotoxic T-lymphocyte apoptotic process|cytotoxic T lymphocyte apoptotic process|cytotoxic T-lymphocyte apoptosis|cytotoxic T lymphocyte apoptosis						nhn	2013-11-04T17:23:48Z						biological_process											owl:Class	
GO:0009187	biolink:NamedThing	cyclic nucleotide metabolic process	The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.	got7fsn_ti	cyclic nucleotide metabolism													biological_process											owl:Class	
GO:0060869	biolink:NamedThing	transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission.	got7fsn_ti	transmembrane receptor protein serine/threonine kinase signalling pathway involved in floral organ abscission						dph	2009-08-12T07:02:07Z						biological_process											owl:Class	
GO:0140122	biolink:NamedThing	regulation of Lewy body formation	Any process that modulates the frequency, rate or extent of Lewy body formation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14160					pg	2017-10-25T07:03:29Z						biological_process											owl:Class	
GO:1900450	biolink:NamedThing	negative regulation of glutamate receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway.	got7fsn_ti	down-regulation of glutamate receptor signaling pathway|down regulation of glutamate receptor signaling pathway|down-regulation of glutamate signalling pathway|negative regulation of glutamate signaling pathway|inhibition of glutamate signaling pathway|negative regulation of glutamate signalling pathway|downregulation of glutamate signaling pathway|inhibition of glutamate receptor signaling pathway|inhibition of glutamate signalling pathway|down regulation of glutamate signalling pathway|downregulation of glutamate receptor signaling pathway|down regulation of glutamate signaling pathway|down-regulation of glutamate signaling pathway|downregulation of glutamate signalling pathway						rl	2012-04-27T03:45:53Z						biological_process											owl:Class	
GO:1904421	biolink:NamedThing	response to D-galactosamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.	got7fsn_ti							sl	2015-07-02T15:38:20Z						biological_process											owl:Class	
GO:0004208	biolink:NamedThing	obsolete caspase-3 activity	OBSOLETE. Catalysis of the cleavage at the terminal bond of the motif: Asp-Xaa-Xaa-Asp-Xaa. Enzymes with this function are members of the peptidase family C14 and they appear to function in the inactivation of proteins involved in cellular repair and homeostasis during the effector stage of apoptosis.	got7fsn_ti	caspase-3 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0015612	biolink:NamedThing	ABC-type L-arabinose transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in).	got7fsn_ti	L-arabinose-importing ATPase activity|L-arabinose porter activity											RHEA:30007|EC:7.5.2.12|EC:7.5.2.13|MetaCyc:ABC-2-RXN		molecular_function											owl:Class	
GO:0090341	biolink:NamedThing	negative regulation of secretion of lysosomal enzymes	Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.	got7fsn_ti							tb	2010-06-01T03:35:57Z						biological_process											owl:Class	
GO:0034123	biolink:NamedThing	positive regulation of toll-like receptor signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.	got7fsn_ti	positive regulation of toll-like receptor signalling pathway|positive regulation of TLR signaling pathway													biological_process											owl:Class	
GO:0052192	biolink:NamedThing	obsolete movement in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of an organism or motile cell on, within or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	locomotion in environment of other organism during symbiotic interaction|movement in environment of other organism during symbiotic interaction				This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:2000958	biolink:NamedThing	negative regulation of cyclodextrin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process.	got7fsn_ti	negative regulation of cyclodextrin catabolism						tt	2011-08-01T02:24:02Z						biological_process											owl:Class	
GO:0006005	biolink:NamedThing	L-fucose biosynthetic process	The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose).	got7fsn_ti	L-fucose synthesis|L-fucose anabolism|L-fucose biosynthesis|L-fucose formation													biological_process											owl:Class	
GO:0060505	biolink:NamedThing	epithelial cell proliferation involved in lung bud dilation	The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud.	got7fsn_ti														biological_process											owl:Class	
GO:0036095	biolink:NamedThing	obsolete positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	transcriptional activation of genes involved in invasive growth				This term was obsoleted because it represents a GO-CAM model.		bf	2012-01-24T10:53:28Z		True				biological_process											owl:Class	
UBERON:0004490	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140694	biolink:NamedThing	non-membrane-bounded organelle assembly	The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle.	got7fsn_ti	non-membrane-bounded organelle formation|non-membrane-enclosed organelle assembly|non-membrane-bounded organelle assembly|non-membrane-enclosed organelle formation	https://github.com/geneontology/go-ontology/issues/21939					pg	2021-08-09T15:30:06Z						biological_process											owl:Class	
GO:0140645	biolink:NamedThing	neutrophic extracellular trap formation	The aggregation, arrangement and bonding together of a set of components to form a neutrophil extracellular trap, a network of extracellular fibers primarily composed of DNA from neutrophils, which bind and neutralizes pathogens.	got7fsn_ti	NET formation	https://github.com/geneontology/go-ontology/issues/21416					pg	2021-05-12T07:08:07Z				http://purl.obolibrary.org/obo/TXPO_0002149		biological_process											owl:Class	
GO:1901480	biolink:NamedThing	oleate transmembrane transporter activity	Enables the transfer of oleate from one side of a membrane to the other.	got7fsn_ti	oleate transporter activity						ab	2012-10-07T17:11:56Z				RHEA:33655		molecular_function											owl:Class	
GO:1900929	biolink:NamedThing	regulation of L-tyrosine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell.	got7fsn_ti	regulation of L-tyrosine import|regulation of L-tyrosine uptake						al	2012-06-13T07:42:52Z						biological_process											owl:Class	
GO:0042186	biolink:NamedThing	o-xylene catabolic process	The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	o-xylene catabolism|o-xylene degradation|ortho-xylene catabolic process|o-xylene breakdown|ortho-xylene catabolism													biological_process											owl:Class	
GO:1904495	biolink:NamedThing	negative regulation of substance P secretion, neurotransmission	Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission.	got7fsn_ti	down-regulation of substance P secretion, neurotransmission|downregulation of substance P secretion, neurotransmission|down regulation of substance P secretion, neurotransmission|inhibition of substance P secretion, neurotransmission						sl	2015-07-21T19:09:10Z						biological_process											owl:Class	
GO:1905226	biolink:NamedThing	regulation of adhesion of symbiont to host epithelial cell	Any process that modulates the frequency, rate or extent of adhesion of symbiont to host epithelial cell.	got7fsn_ti							pga	2016-06-07T13:15:08Z						biological_process											owl:Class	
GO:1904220	biolink:NamedThing	regulation of serine C-palmitoyltransferase activity	Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity.	got7fsn_ti	regulation of SPT|regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|regulation of serine palmitoyltransferase|regulation of 3-oxosphinganine synthetase activity				Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability		rl	2015-05-15T08:27:33Z						biological_process											owl:Class	
GO:1902722	biolink:NamedThing	positive regulation of prolactin secretion	Any process that activates or increases the frequency, rate or extent of prolactin secretion.	got7fsn_ti	up-regulation of prolactin secretion|up regulation of prolactin secretion|upregulation of prolactin secretion|activation of prolactin secretion						mr	2014-02-24T16:09:37Z						biological_process											owl:Class	
GO:1903135	biolink:NamedThing	cupric ion binding	Binding to a cupric ion, copper(2+).	got7fsn_ti	copper(2+)binding|Cu(II) binding|Cu(2+) binding						bf	2014-06-26T14:38:16Z						molecular_function											owl:Class	
GO:0005517	biolink:NamedThing	obsolete calmodulin inhibitor activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	calmodulin inhibitor activity				This term was made obsolete because it refers to a non-existent molecular function term, 'calmodulin activity'.	GO:0005516				True				molecular_function											owl:Class	
GO:0002881	biolink:NamedThing	negative regulation of chronic inflammatory response to non-antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.	got7fsn_ti	down-regulation of chronic inflammatory response to non-antigenic stimulus|downregulation of chronic inflammatory response to non-antigenic stimulus|inhibition of chronic inflammatory response to non-antigenic stimulus|down regulation of chronic inflammatory response to non-antigenic stimulus													biological_process											owl:Class	
GO:0110076	biolink:NamedThing	negative regulation of ferroptosis	Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis.	got7fsn_ti							kmv	2018-01-11T18:00:05Z						biological_process											owl:Class	
GO:0070244	biolink:NamedThing	negative regulation of thymocyte apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.	got7fsn_ti	down regulation of thymocyte apoptosis|negative regulation of thymocyte apoptosis|negative regulation of immature T cell apoptosis|downregulation of thymocyte apoptosis|down-regulation of thymocyte apoptosis|inhibition of thymocyte apoptosis				Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).									biological_process											owl:Class	
GO:2001270	biolink:NamedThing	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.	got7fsn_ti	regulation of effector caspase activity						pr	2011-12-13T07:59:36Z						biological_process											owl:Class	
GO:0008162	biolink:NamedThing	obsolete cyclodiene resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cyclodiene resistance			GO:0046682	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0035934	biolink:NamedThing	corticosterone secretion	The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.	got7fsn_ti							bf	2011-07-20T01:09:31Z						biological_process											owl:Class	
GO:1903314	biolink:NamedThing	regulation of nitrogen cycle metabolic process	Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process.	got7fsn_ti							vw	2014-08-18T12:57:34Z						biological_process											owl:Class	
GO:1900391	biolink:NamedThing	obsolete regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cAMP-mediated signaling.	got7fsn_ti	regulation of cAMP-mediated signalling by regulation of transcription from RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14279			The reason for obsoletion is that cAMP-mediated signaling is not mediated by transcription from RNA polII promoter.		mah	2012-04-18T04:19:39Z		True				biological_process											owl:Class	
GO:0001804	biolink:NamedThing	negative regulation of type III hypersensitivity	Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.	got7fsn_ti	down regulation of type III hypersensitivity|down-regulation of type III hypersensitivity|inhibition of type III hypersensitivity|downregulation of type III hypersensitivity													biological_process											owl:Class	
GO:0050762	biolink:NamedThing	depsipeptide catabolic process	The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.	got7fsn_ti	depsipeptide degradation|depsipeptide breakdown|depsipeptide catabolism													biological_process											owl:Class	
GO:0021883	biolink:NamedThing	obsolete cell cycle arrest of committed forebrain neuronal progenitor cell	OBSOLETE. The process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20988			This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0001087	biolink:NamedThing	obsolete transcription factor activity, TFIIB-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIB class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	got7fsn_ti	TFIIB-class binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001093	krc	2010-10-28T02:18:00Z		True				molecular_function											owl:Class	
GO:1903891	biolink:NamedThing	regulation of ATF6-mediated unfolded protein response	Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response.	got7fsn_ti	regulation of ATF6-alpha UPR branch|regulation of UPR signaling by ATF6 stress sensor|regulation of ATF6 signal transduction pathway|regulation of ATF6 signaling in response to endoplasmic reticulum stress|regulation of ATF6-beta UPR branch|regulation of ATF6 branch of UPR|regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|regulation of activating transcription factor 6 signaling in unfolded protein response						bf	2015-02-09T10:17:15Z						biological_process											owl:Class	
GO:0090362	biolink:NamedThing	positive regulation of platelet-derived growth factor production	Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti							tb	2010-07-12T10:32:27Z						biological_process											owl:Class	
GO:1900984	biolink:NamedThing	vindoline catabolic process	The chemical reactions and pathways resulting in the breakdown of vindoline.	got7fsn_ti	vindoline breakdown|vindoline catabolism|vindoline degradation						yaf	2012-06-14T09:16:56Z						biological_process											owl:Class	
GO:2000906	biolink:NamedThing	positive regulation of starch metabolic process	Any process that activates or increases the frequency, rate or extent of starch metabolic process.	got7fsn_ti	positive regulation of starch metabolism						tb	2011-07-28T11:33:19Z						biological_process											owl:Class	
GO:0051068	biolink:NamedThing	dihydrolipoamide metabolic process	The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor.	got7fsn_ti	dihydrothioctamide metabolism|dihydrolipoamide metabolism|dihydrolipoamide reduction|dihydrothioctamide metabolic process													biological_process											owl:Class	
GO:0030248	biolink:NamedThing	cellulose binding	Binding to cellulose.	got7fsn_ti														molecular_function											owl:Class	
GO:0052486	biolink:NamedThing	obsolete negative regulation by organism of symbiont innate immunity	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the symbiont organism, the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of symbiont innate immunity|negative regulation of symbiont innate immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1904511	biolink:NamedThing	cytoplasmic microtubule plus-end	Any microtubule plus-end that is part of a cytoplasmic microtubule.	got7fsn_ti	growing microtubule plus end of cytoplasmic microtubule|microtubule plus end of non-spindle-associated astral microtubule|growing microtubule plus end of non-spindle-associated astral microtubule|microtubule plus-end of cytoplasmic microtubule|microtubule plus end of cytoplasmic microtubule|microtubule plus-end of non-spindle-associated astral microtubule						mah	2015-07-27T13:05:11Z						cellular_component											owl:Class	
GO:1990496	biolink:NamedThing	obsolete regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly	OBSOLETE. An actin filament organization process that contributes to regulation of actomyosin contractile ring assembly during mitotic cytokinesis.	got7fsn_ti	regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-09-25T09:21:57Z		True				biological_process											owl:Class	
GO:1902725	biolink:NamedThing	negative regulation of satellite cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation.	got7fsn_ti	downregulation of satellite cell differentiation|down-regulation of satellite cell differentiation|down regulation of satellite cell differentiation|inhibition of satellite cell differentiation						mr	2014-02-24T16:10:05Z						biological_process											owl:Class	
GO:0009781	biolink:NamedThing	obsolete photosynthetic water oxidation	OBSOLETE. Processes by which a molecule of water is oxidized during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.	got7fsn_ti	photosynthetic water oxidation			GO:0010242	This term was made obsolete because it represents a molecular function.					True				biological_process											owl:Class	
GO:0042841	biolink:NamedThing	D-glucuronate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate.	got7fsn_ti	D-glucuronate anabolism|D-glucuronate biosynthesis|D-glucuronate synthesis|D-glucuronate formation													biological_process											owl:Class	
GO:1900523	biolink:NamedThing	positive regulation of response to amylopectin	Any process that activates or increases the frequency, rate or extent of response to amylopectin.	got7fsn_ti	up regulation of response to amylopectin|up-regulation of response to amylopectin|activation of response to amylopectin|upregulation of response to amylopectin						tt	2012-05-02T04:14:11Z						biological_process											owl:Class	
GO:0010916	biolink:NamedThing	negative regulation of very-low-density lipoprotein particle clearance	Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti	negative regulation of VLDL particle clearance|negative regulation of VLDL clearance													biological_process											owl:Class	
GO:0003971	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901798	biolink:NamedThing	positive regulation of signal transduction by p53 class mediator	Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.	got7fsn_ti	upregulation of signal transduction by p53 class mediator|up-regulation of signal transduction by p53 class mediator|activation of signal transduction by p53 class mediator|up regulation of signal transduction by p53 class mediator						hjd	2013-01-18T21:51:48Z						biological_process											owl:Class	
GO:0070656	biolink:NamedThing	mechanoreceptor differentiation involved in mechanosensory epithelium regeneration	Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.	got7fsn_ti							mah	2009-05-28T04:08:13Z						biological_process											owl:Class	
GO:0106039	biolink:NamedThing	obsolete vesicle fusion involved in vesicle assembly	OBSOLETE. A process carried out at the cellular level, which is the final step in vesicle assembly. Vesicle fusion occurs when a newly assembled vesicle closes up, following vesicle vesicle scission (GO:0099050).	got7fsn_ti					This term was made obsolete becausethat 'fusion' should only be used for two membranes getting joined together, whereas in this case it would be one membrane 'closing/sealing up'.		hjd	2017-07-17T13:56:31Z		True				biological_process											owl:Class	
GO:0007573	biolink:NamedThing	obsolete age dependent increased protein content	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	age dependent increased protein content				This term was made obsolete because it does not describe a biological process.	GO:0007571				True				biological_process											owl:Class	
GO:0051079	biolink:NamedThing	meiosis I nuclear membrane disassembly	The controlled breakdown of the nuclear membranes during the first division of meiosis.	got7fsn_ti	meiosis I nuclear envelope breakdown|meiosis I nuclear envelope catabolism|meiosis I nuclear envelope degradation|meiosis I nuclear envelope disassembly													biological_process											owl:Class	
GO:1901806	biolink:NamedThing	beta-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucoside.	got7fsn_ti	beta-glucoside synthesis|beta-glucoside biosynthesis|beta-glucoside formation|beta-glucoside anabolism						yaf	2013-01-22T10:10:30Z						biological_process											owl:Class	
GO:1900854	biolink:NamedThing	positive regulation of terrequinone A biosynthetic process	Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process.	got7fsn_ti	up-regulation of terrequinone A biosynthetic process|upregulation of terrequinone A biosynthetic process|up regulation of terrequinone A biosynthetic process						di	2012-06-07T09:47:38Z						biological_process											owl:Class	
CHEBI:61006	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000349	biolink:NamedThing	negative regulation of CD40 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.	got7fsn_ti	negative regulation of CD40 signalling pathway						mah	2011-02-03T10:29:44Z						biological_process											owl:Class	
GO:2001134	biolink:NamedThing	methane biosynthetic process from carbon monoxide	The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide.	got7fsn_ti							jl	2011-10-13T12:36:20Z						biological_process											owl:Class	
GO:1903284	biolink:NamedThing	positive regulation of glutathione peroxidase activity	Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity.	got7fsn_ti	upregulation of glutathione peroxidase activity|up regulation of non-selenium glutathione peroxidase activity|up regulation of GSH peroxidase activity|activation of reduced glutathione peroxidase activity|up-regulation of glutathione:hydrogen-peroxide oxidoreductase activity|up-regulation of glutathione peroxidase activity|activation of non-selenium glutathione peroxidase activity|positive regulation of non-selenium glutathione peroxidase activity|up regulation of reduced glutathione peroxidase activity|activation of selenium-glutathione peroxidase activity|upregulation of non-selenium glutathione peroxidase activity|positive regulation of GSH peroxidase activity|up-regulation of reduced glutathione peroxidase activity|up-regulation of non-selenium glutathione peroxidase activity|upregulation of reduced glutathione peroxidase activity|activation of GSH peroxidase activity|activation of glutathione peroxidase activity|positive regulation of selenium-glutathione peroxidase activity|up regulation of glutathione:hydrogen-peroxide oxidoreductase activity|positive regulation of glutathione:hydrogen-peroxide oxidoreductase activity|positive regulation of reduced glutathione peroxidase activity|up regulation of glutathione peroxidase activity|up-regulation of GSH peroxidase activity|upregulation of selenium-glutathione peroxidase activity|upregulation of GSH peroxidase activity|upregulation of glutathione:hydrogen-peroxide oxidoreductase activity|enhancement of GPX activity|activation of glutathione:hydrogen-peroxide oxidoreductase activity|up-regulation of selenium-glutathione peroxidase activity|up regulation of selenium-glutathione peroxidase activity						bf	2014-08-11T13:14:30Z						biological_process											owl:Class	
GO:1901640	biolink:NamedThing	XTP binding	Binding to XTP.	got7fsn_ti							tb	2012-11-15T22:56:35Z						molecular_function											owl:Class	
GO:0097605	biolink:NamedThing	obsolete regulation of nuclear envelope permeability	OBSOLETE. Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.	got7fsn_ti	regulation of nuclear membrane permeability				The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it.		pr	2014-05-14T15:41:44Z		True				biological_process											owl:Class	
GO:1903370	biolink:NamedThing	positive regulation of foraging behavior	Any process that activates or increases the frequency, rate or extent of foraging behavior.	got7fsn_ti	up-regulation of foraging behavior|upregulation of foraging behavior|activation of foraging behavior|up regulation of foraging behavior						mr	2014-08-22T03:03:20Z						biological_process											owl:Class	
GO:0086099	biolink:NamedThing	phospholipase C-activating angiotensin-activated signaling pathway involved in heart process	An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores.	got7fsn_ti	phospholipase C-activating angiotensin-mediated signaling pathway involved in heart process|cardiac angiotensin receptor signaling pathway via activation of PLC|PLC-activating angiotensin receptor signaling pathway involved in heart process|Gq-coupled angiotensin receptor signaling pathway involved in heart process|angiotensin receptor signaling pathway via activation of phospholipase C involved in heart process						bf							biological_process											owl:Class	
GO:1903018	biolink:NamedThing	regulation of glycoprotein metabolic process	Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.	got7fsn_ti	regulation of glycoprotein metabolism				human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein		rl	2014-05-14T18:44:19Z						biological_process											owl:Class	
GO:0043651	biolink:NamedThing	linoleic acid metabolic process	The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.	got7fsn_ti	linoleic acid metabolism											Wikipedia:Linoleic_acid		biological_process											owl:Class	
GO:2000630	biolink:NamedThing	positive regulation of miRNA metabolic process	Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.	got7fsn_ti	positive regulation of microRNA metabolic process						dph	2011-04-18T03:48:01Z						biological_process											owl:Class	
GO:0033467	biolink:NamedThing	CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process	The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.	got7fsn_ti	CMP-keto-3-deoxy-D-manno-octulosonic acid metabolism|CMP-KDO metabolic process|CMP-ketodeoxyoctanoate metabolic process													biological_process											owl:Class	
GO:1901332	biolink:NamedThing	negative regulation of lateral root development	Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development.	got7fsn_ti	downregulation of lateral root development|inhibition of lateral root development|down regulation of lateral root development|down-regulation of lateral root development						tb	2012-09-01T00:58:37Z						biological_process											owl:Class	
GO:0075116	biolink:NamedThing	obsolete induction by symbiont of host transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|positive regulation by symbiont of host transmembrane receptor-mediated cAMP signaling|positive regulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|upregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|promotion by symbiont of host transmembrane receptor-mediated cAMP signal transduction|stimulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction				The reason for obsoletion is that there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:2000617	biolink:NamedThing	positive regulation of histone H3-K9 acetylation	Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation.	got7fsn_ti	positive regulation of histone H3 acetylation at K9|positive regulation of histone H3K9 acetylation						vk	2011-04-18T03:16:07Z						biological_process											owl:Class	
GO:1900926	biolink:NamedThing	regulation of L-threonine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-threonine import into cell.	got7fsn_ti	regulation of L-threonine uptake|regulation of L-threonine import						al	2012-06-13T07:41:32Z						biological_process											owl:Class	
GO:1905469	biolink:NamedThing	negative regulation of clathrin-coated pit assembly	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-coated pit assembly.	got7fsn_ti	down regulation of coated pit formation|down-regulation of clathrin-coated pit assembly|negative regulation of clathrin-coated pit formation|inhibition of clathrin-coated pit assembly|downregulation of coated pit formation|negative regulation of coated pit formation|negative regulation of coated pit assembly|down regulation of clathrin-coated pit assembly|down-regulation of coated pit formation|inhibition of clathrin-coated pit formation|inhibition of coated pit formation|downregulation of coated pit assembly|downregulation of clathrin-coated pit formation|down-regulation of clathrin-coated pit formation|down-regulation of coated pit assembly|inhibition of coated pit assembly|downregulation of clathrin-coated pit assembly|down regulation of coated pit assembly|down regulation of clathrin-coated pit formation						bf	2016-09-20T10:04:45Z						biological_process											owl:Class	
GO:1902340	biolink:NamedThing	negative regulation of chromosome condensation	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.	got7fsn_ti	downregulation of chromosome condensation|inhibition of nuclear chromosome condensation|down-regulation of nuclear chromosome condensation|down regulation of nuclear chromosome condensation|negative regulation of eukaryotic chromosome condensation|negative regulation of nuclear chromosome condensation|down regulation of eukaryotic chromosome condensation|downregulation of nuclear chromosome condensation|inhibition of chromosome condensation|down-regulation of eukaryotic chromosome condensation|downregulation of eukaryotic chromosome condensation|down regulation of chromosome condensation|inhibition of eukaryotic chromosome condensation|down-regulation of chromosome condensation						dgf	2013-07-29T20:54:14Z						biological_process											owl:Class	
GO:0089705	biolink:NamedThing	protein localization to outer membrane	A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0021913	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the commitment of a cell to become an interneuron in the ventral spinal cord.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0021521				True				biological_process											owl:Class	
GO:0048031	biolink:NamedThing	trisaccharide binding	Binding to a trisaccharide. Trisaccharides are sugars composed of three monosaccharide units.	got7fsn_ti														molecular_function											owl:Class	
GO:0046492	biolink:NamedThing	heme B metabolic process	The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.	got7fsn_ti	haem B metabolism|haem B metabolic process|heme B metabolism|protoheme metabolism|protoheme metabolic process													biological_process											owl:Class	
GO:0075194	biolink:NamedThing	positive regulation of haustorium mother cell formation	Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of haustorium mother cell formation on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0032006	biolink:NamedThing	regulation of TOR signaling	Any process that modulates the frequency, rate or extent of TOR signaling.	got7fsn_ti	regulation of TOR signalling pathway|regulation of TOR signaling cascade|regulation of target of rapamycin signaling pathway|regulation of target of rapamycin signalling pathway|regulation of TOR signaling pathway													biological_process											owl:Class	
GO:0100059	biolink:NamedThing	obsolete negative regulation of phenotypic switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phenotypic switching.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0006662	biolink:NamedThing	glycerol ether metabolic process	The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.	got7fsn_ti	glycerol ether metabolism													biological_process											owl:Class	
GO:1901504	biolink:NamedThing	triazole transport	The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							pr	2012-10-17T09:47:46Z						biological_process											owl:Class	
GO:0052359	biolink:NamedThing	obsolete catabolism by organism of glucan in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism by organism of glucan in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0034078	biolink:NamedThing	butanediol catabolic process	The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.	got7fsn_ti	butylene glycol catabolic process|butanediol breakdown|butanediol utilization|butylene glycol catabolism|butanediol catabolism|butanediol degradation													biological_process											owl:Class	
GO:0050898	biolink:NamedThing	nitrile metabolic process	The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.	got7fsn_ti	nitrile metabolism													biological_process											owl:Class	
GO:0050759	biolink:NamedThing	positive regulation of thymidylate synthase biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.	got7fsn_ti	positive regulation of thymidylate synthase formation|stimulation of thymidylate synthase biosynthetic process|up regulation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase anabolism|positive regulation of thymidylate synthase biosynthesis|positive regulation of thymidylate synthase synthesis|activation of thymidylate synthase biosynthetic process|upregulation of thymidylate synthase biosynthetic process|up-regulation of thymidylate synthase biosynthetic process													biological_process											owl:Class	
GO:0004894	biolink:NamedThing	obsolete T cell receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	T cell receptor activity				This term was made obsolete because it describes a receptor type, and not an activity.	GO:0032394|GO:0032395|GO:0042605				True				molecular_function											owl:Class	
GO:0006729	biolink:NamedThing	tetrahydrobiopterin biosynthetic process	The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.	got7fsn_ti	tetrahydrobiopterin synthesis|tetrahydrobiopterin formation|5,6,7,8-tetrahydrobiopterin biosynthetic process|tetrahydrobiopterin biosynthesis|tetrahydrobiopterin anabolism													biological_process											owl:Class	
GO:0033570	biolink:NamedThing	obsolete transferrin transmembrane transporter activity	OBSOLETE. Enables the transfer of transferrin from one side of a membrane to the other.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17157			This term was obsoleted because there is no evidence that this function exists.					True				molecular_function											owl:Class	
GO:2000918	biolink:NamedThing	regulation of glucuronoarabinoxylan catabolic process	Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process.	got7fsn_ti	regulation of glucuronoarabinoxylan catabolism						tt	2011-08-01T12:36:47Z						biological_process											owl:Class	
GO:1905240	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.	got7fsn_ti	downregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt signaling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation						rph	2016-06-08T10:26:41Z						biological_process											owl:Class	
GO:0008464	biolink:NamedThing	obsolete gamma-glutamyl hydrolase activity	OBSOLETE. Catalysis of the cleavage of a gamma-glutamyl bond to release an unsubstituted C-terminal amino acid.	got7fsn_ti	poly(gamma-glutamic acid) endohydrolase activity|folic acid conjugase activity|carboxypeptidase G activity|gamma-Glu-X carboxypeptidase activity|lysosomal gamma-glutamyl carboxypeptidase activity|folate conjugase activity|polyglutamate hydrolase activity|gamma-glutamyl hydrolase activity|poly(glutamic acid) hydrolase II|pteroylpoly-gamma-glutamyl hydrolase activity|pteroyl-poly-gamma-glutamate hydrolase activity|conjugase activity|pteroyl-poly-alpha-glutamate hydrolase activity			GO:0008242	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1902988	biolink:NamedThing	neurofibrillary tangle assembly	The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle.	got7fsn_ti	flame-shaped neurofibrillary tangle formation|flame-shaped neurofibrillary tangle assembly|star-shaped neurofibrillary tangle formation|star-shaped neurofibrillary tangle assembly|neurofibrillary tangle formation				Neurofibrillary tangles have been found in aging population; their formation is increased in Alzheimer's disease patients (and in other neurological diseases) compared to normal controls (see PMID:848276 and PMID:8584267).		sjp	2014-05-08T09:19:51Z						biological_process											owl:Class	
GO:0031375	biolink:NamedThing	obsolete type II fatty acid synthase complex	OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity.	got7fsn_ti	type II FAS complex|type II FAS|type II fatty acid synthase|type II fatty acid synthase complex				Type II refers to the type of fatty acid synthase. Type I is in a complex, type II is not.					True				cellular_component											owl:Class	
GO:0051901	biolink:NamedThing	positive regulation of mitochondrial depolarization	Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.	got7fsn_ti	upregulation of mitochondrial depolarization|activation of mitochondrial depolarization|up-regulation of mitochondrial depolarization|up regulation of mitochondrial depolarization|stimulation of mitochondrial depolarization													biological_process											owl:Class	
GO:1901467	biolink:NamedThing	negative regulation of ferulate catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process.	got7fsn_ti	negative regulation of ferulate catabolism|inhibition of ferulate catabolism|downregulation of ferulate degradation|inhibition of ferulate catabolic process|down regulation of ferulate breakdown|down regulation of ferulate catabolism|down-regulation of ferulate breakdown|downregulation of ferulate catabolic process|inhibition of ferulate breakdown|down-regulation of ferulate catabolism|down-regulation of ferulate catabolic process|down regulation of ferulate degradation|down-regulation of ferulate degradation|negative regulation of ferulate degradation|inhibition of ferulate degradation|down regulation of ferulate catabolic process|negative regulation of ferulate breakdown|downregulation of ferulate catabolism|downregulation of ferulate breakdown						tt	2012-10-02T14:38:38Z						biological_process											owl:Class	
GO:0031114	biolink:NamedThing	regulation of microtubule depolymerization	Any process that modulates the frequency, rate or extent of microtubule depolymerization.	got7fsn_ti	regulation of microtubule disassembly													biological_process											owl:Class	
GO:2000058	biolink:NamedThing	regulation of ubiquitin-dependent protein catabolic process	Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process.	got7fsn_ti	regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown|regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation|regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|regulation of protein degradation tagging activity|regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitination during ubiquitin-dependent protein degradation|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process						jl	2010-08-20T01:23:46Z						biological_process											owl:Class	
GO:0009977	biolink:NamedThing	proton motive force dependent protein transmembrane transporter activity	Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane.	got7fsn_ti	twin-arginine targeting transmembrane transporter activity|arginine targeting transmembrane transporter activity|delta-pH-dependent protein transporter activity|pH-dependent protein transporter activity										GO:0015557			molecular_function											owl:Class	
GO:0045218	biolink:NamedThing	zonula adherens maintenance	Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells.	got7fsn_ti														biological_process											owl:Class	
GO:0015522	biolink:NamedThing	obsolete hydrophobic uncoupler:proton antiporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS.	got7fsn_ti	hydrophobic uncoupler:hydrogen antiporter activity				The reason for obsoletion is that this term represented a specific protein in TCDB, 2.A.1.2.9, which actually is a sugar transporter that seems to also function as a multidrug efflux protein.					True				molecular_function											owl:Class	
GO:1901809	biolink:NamedThing	capsanthin biosynthetic process	The chemical reactions and pathways resulting in the formation of capsanthin.	got7fsn_ti	capsanthin formation|capsanthin anabolism|capsanthin synthesis|capsanthin biosynthesis						yaf	2013-01-22T10:21:50Z						biological_process											owl:Class	
GO:1902397	biolink:NamedThing	obsolete detection of stimulus involved in meiotic spindle checkpoint	OBSOLETE. Any detection of stimulus that is involved in meiotic spindle checkpoint.	got7fsn_ti	stimulus detection involved in meiotic spindle checkpoint|stimulus sensing involved in meiotic spindle checkpoint|perception of stimulus involved in meiotic spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		jl	2013-09-12T12:01:32Z		True				biological_process											owl:Class	
GO:0070346	biolink:NamedThing	positive regulation of fat cell proliferation	Any process that activates or increases the rate or extent of fat cell proliferation.	got7fsn_ti	up-regulation of fat cell proliferation|stimulation of fat cell proliferation|positive regulation of adipose cell proliferation|up regulation of fat cell proliferation|positive regulation of adipocyte proliferation|activation of fat cell proliferation|upregulation of fat cell proliferation													biological_process											owl:Class	
GO:0010143	biolink:NamedThing	cutin biosynthetic process	The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants.	got7fsn_ti	cutin biosynthesis|cutin formation|cutin anabolism|cutin synthesis											MetaCyc:PWY-321		biological_process											owl:Class	
GO:1904161	biolink:NamedThing	DNA synthesis involved in UV-damage excision repair	Any DNA synthesis that is involved in UV-damage excision repair.	got7fsn_ti	mitotic DNA repair synthesis involved in UVDE-dependent excision repair|DNA synthesis during UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis involved in AER|DNA synthesis involved in UVER|DNA synthesis involved in UVDE-dependent excision repair|DNA synthesis during UVER|mitotic DNA repair synthesis involved in UVER|DNA synthesis involved in UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis during UV-damage excision repair|mitotic DNA repair synthesis involved in UV-damage excision repair|DNA synthesis involved in alternative excision repair|mitotic DNA repair synthesis involved in UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis during UVDE-dependent excision repair						mah	2015-04-21T14:53:12Z						biological_process											owl:Class	
GO:1901581	biolink:NamedThing	negative regulation of telomeric RNA transcription from RNA pol II promoter	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.	got7fsn_ti	down regulation of telomeric RNA transcription from RNA pol II promoter|inhibition of telomeric RNA transcription from Pol II promoter|down regulation of telomeric RNA transcription from Pol II promoter|down-regulation of telomeric RNA transcription from RNA pol II promoter|down-regulation of telomeric RNA transcription from Pol II promoter|downregulation of telomeric RNA transcription from RNA pol II promoter|negative regulation of telomeric RNA transcription from Pol II promoter|inhibition of telomeric RNA transcription from RNA pol II promoter|downregulation of telomeric RNA transcription from Pol II promoter						al	2012-11-06T11:07:21Z						biological_process											owl:Class	
GO:0031441	biolink:NamedThing	negative regulation of mRNA 3'-end processing	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.	got7fsn_ti	downregulation of mRNA 3'-end processing|down-regulation of mRNA 3'-end processing|down regulation of mRNA 3'-end processing|inhibition of mRNA 3'-end processing													biological_process											owl:Class	
GO:0071832	biolink:NamedThing	peptide pheromone export involved in regulation of conjugation	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.	got7fsn_ti							mah	2010-09-09T11:06:46Z						biological_process											owl:Class	
CHEBI:4638	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060781	biolink:NamedThing	mesenchymal cell proliferation involved in prostate gland development	The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.	got7fsn_ti							dph	2009-07-28T11:50:56Z						biological_process											owl:Class	
GO:0071662	biolink:NamedThing	negative regulation of granzyme B production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B.	got7fsn_ti							mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:1905246	biolink:NamedThing	negative regulation of aspartic-type peptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity.	got7fsn_ti	down regulation of aspartic-type peptidase activity|downregulation of aspartic-type peptidase activity|pepsin inhibitor|inhibition of aspartic-type peptidase activity|down-regulation of aspartic-type peptidase activity						jl	2016-06-09T11:55:47Z						biological_process											owl:Class	
GO:0060904	biolink:NamedThing	regulation of protein folding in endoplasmic reticulum	Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).	got7fsn_ti							dph	2009-08-14T01:12:00Z						biological_process											owl:Class	
GO:0106061	biolink:NamedThing	negative regulation of exit from meiosis	Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis.	got7fsn_ti							hjd	2017-10-18T16:51:15Z						biological_process											owl:Class	
GO:2001067	biolink:NamedThing	pullulan binding	Binding to pullulan.	got7fsn_ti							jl	2011-09-14T11:50:06Z						molecular_function											owl:Class	
GO:0048346	biolink:NamedThing	positive regulation of paraxial mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination.	got7fsn_ti	up-regulation of paraxial mesodermal cell fate determination|stimulation of paraxial mesodermal cell fate determination|activation of paraxial mesodermal cell fate determination|up regulation of paraxial mesodermal cell fate determination|upregulation of paraxial mesodermal cell fate determination													biological_process											owl:Class	
GO:0002875	biolink:NamedThing	negative regulation of chronic inflammatory response to antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.	got7fsn_ti	down-regulation of chronic inflammatory response to antigenic stimulus|down regulation of chronic inflammatory response to antigenic stimulus|inhibition of chronic inflammatory response to antigenic stimulus|downregulation of chronic inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:0080179	biolink:NamedThing	1-methylguanosine metabolic process	The chemical reactions and pathways involving 1-methylguanosine.	got7fsn_ti							dhl	2011-04-28T04:38:13Z						biological_process											owl:Class	
GO:2000979	biolink:NamedThing	positive regulation of forebrain neuron differentiation	Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation.	got7fsn_ti							yaf	2011-08-03T12:09:19Z						biological_process											owl:Class	
GO:0046094	biolink:NamedThing	deoxyinosine metabolic process	The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside.	got7fsn_ti	deoxyinosine metabolism													biological_process											owl:Class	
GO:0043051	biolink:NamedThing	regulation of pharyngeal pumping	Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.	got7fsn_ti														biological_process											owl:Class	
GO:0000051	biolink:NamedThing	obsolete urea cycle intermediate metabolic process	OBSOLETE. The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea.	got7fsn_ti	urea cycle intermediate metabolism|urea cycle intermediate metabolic process				This term was made obsolete because it is a grouping term that is not useful, but has caused true path violations.					True				biological_process											owl:Class	
GO:1902211	biolink:NamedThing	regulation of prolactin signaling pathway	Any process that modulates the frequency, rate or extent of prolactin signaling pathway.	got7fsn_ti	regulation of prolactin-mediated signaling pathway|regulation of PRL signaling pathway						lb	2013-06-12T10:10:07Z						biological_process											owl:Class	
GO:0140330	biolink:NamedThing	xenobiotic detoxification by transmembrane export across the cell outer membrane	A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane.	got7fsn_ti							pg	2019-05-03T10:35:57Z						biological_process											owl:Class	
GO:1901621	biolink:NamedThing	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.	got7fsn_ti	negative regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|negative regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|down-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|inhibition of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|inhibition of hh signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of smoothened signalling pathway involved in dorsal/ventral neural tube patterning						krc	2012-11-13T20:12:01Z						biological_process											owl:Class	
CHEBI:64553	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007115	biolink:NamedThing	obsolete bud site selection/establishment of cell polarity (sensu Saccharomyces)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	bud site selection/establishment of cell polarity (sensu Saccharomyces)				This term was made obsolete because it represents two processes.	GO:0030010|GO:0000282				True				biological_process											owl:Class	
GO:0032540	biolink:NamedThing	positive regulation of host-seeking behavior	Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism.	got7fsn_ti	up-regulation of host-seeking behavior|stimulation of host-seeking behavior|up regulation of host-seeking behavior|activation of host-seeking behavior|upregulation of host-seeking behavior|positive regulation of host-seeking behaviour													biological_process											owl:Class	
CL:0002131	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032014	biolink:NamedThing	positive regulation of ARF protein signal transduction	Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.	got7fsn_ti	upregulation of ARF protein signal transduction|stimulation of ARF protein signal transduction|activation of ARF protein signal transduction|up regulation of ARF protein signal transduction|up-regulation of ARF protein signal transduction													biological_process											owl:Class	
GO:0009487	biolink:NamedThing	obsolete glutaredoxin	OBSOLETE. A small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase.	got7fsn_ti	glutaredoxin				This term was made obsolete because it represents a gene product.	GO:0015038|GO:0015036|GO:0003756				True				molecular_function											owl:Class	
GO:0016094	biolink:NamedThing	polyprenol biosynthetic process	The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.	got7fsn_ti	polyprenol anabolism|polyprenol synthesis|polyprenol formation|polyprenol biosynthesis													biological_process											owl:Class	
GO:1904393	biolink:NamedThing	regulation of skeletal muscle acetylcholine-gated channel clustering	Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.	got7fsn_ti	regulation of skeletal muscle AChR clustering|regulation of skeletal muscle nicotinic acetylcholine receptor clustering						sl	2015-06-23T19:23:25Z						biological_process											owl:Class	
GO:0006078	biolink:NamedThing	(1->6)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.	got7fsn_ti	1,6-beta-glucan synthesis|1,6-beta-glucan biosynthesis|beta-1,6 glucan formation|1,6-beta-glucan formation|beta-1,6 glucan biosynthesis|1,6-beta-glucan biosynthetic process|beta-1,6 glucan anabolism|1,6-beta-glucan anabolism|beta-1,6 glucan biosynthetic process|beta-1,6 glucan synthesis													biological_process											owl:Class	
GO:0120008	biolink:NamedThing	positive regulation of glutamatergic neuron differentiation	Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13107					krc	2017-03-01T16:35:45Z						biological_process											owl:Class	
GO:1905825	biolink:NamedThing	regulation of selenocysteine metabolic process	Any process that modulates the frequency, rate or extent of selenocysteine metabolic process.	got7fsn_ti	regulation of selenocysteine metabolism						sl	2017-01-16T19:01:34Z						biological_process											owl:Class	
UBERON:0003216	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905538	biolink:NamedThing	polysome binding	Binding to a polysome.	got7fsn_ti	polyribosome binding						bc	2016-10-07T14:02:53Z						molecular_function											owl:Class	
GO:0004625	biolink:NamedThing	obsolete calcium-dependent secreted phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	got7fsn_ti	calcium-dependent secreted phospholipase A2 activity				This term was made obsolete because it represents component and function information.	GO:0047498|GO:0005576				True				molecular_function											owl:Class	
GO:0005527	biolink:NamedThing	macrolide binding	Binding to a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.	got7fsn_ti														molecular_function											owl:Class	
GO:2000421	biolink:NamedThing	positive regulation of eosinophil extravasation	Any process that activates or increases the frequency, rate or extent of eosinophil extravasation.	got7fsn_ti							mah	2011-02-23T01:47:42Z						biological_process											owl:Class	
GO:1905473	biolink:NamedThing	positive regulation of histone H3-K79 dimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K79 dimethylation.	got7fsn_ti	activation of histone H3 K79 dimethylation|up regulation of histone lysine H3 K79 dimethylation|positive regulation of histone H3 K79 dimethylation|positive regulation of histone lysine H3 K79 dimethylation|upregulation of histone H3-K79 dimethylation|up-regulation of histone lysine H3 K79 dimethylation|up-regulation of histone H3-K79 dimethylation|up regulation of histone H3 K79 dimethylation|activation of histone lysine H3 K79 dimethylation|up-regulation of histone H3 K79 dimethylation|activation of histone H3-K79 dimethylation|upregulation of histone H3 K79 dimethylation|up regulation of histone H3-K79 dimethylation|upregulation of histone lysine H3 K79 dimethylation						hbye	2016-09-21T15:27:17Z						biological_process											owl:Class	
GO:1902776	biolink:NamedThing	6-sulfoquinovose(1-) metabolic process	The chemical reactions and pathways involving 6-sulfoquinovose(1-).	got7fsn_ti	6-sulfoquinovose(1-) metabolism						dph	2014-03-18T17:45:56Z						biological_process											owl:Class	
GO:0150129	biolink:NamedThing	positive regulation of interleukin-33 production	Any process that activates or increases the frequency, rate or extent of interleukin-33 production.	got7fsn_ti	positive regulation of interleukin-33 secretion|positive regulation of interleukin-33 biosynthetic process						bc	2019-12-03T05:54:37Z			GO:0150132|GO:0150125			biological_process											owl:Class	
GO:1904399	biolink:NamedThing	heparan sulfate binding	Binding to heparan sulfate.	got7fsn_ti							sl	2015-06-23T19:56:54Z						molecular_function											owl:Class	
GO:1901155	biolink:NamedThing	paromomycin biosynthetic process	The chemical reactions and pathways resulting in the formation of paromomycin.	got7fsn_ti	paromomycin anabolism|paromomycin synthesis|paromomycin formation|paromomycin biosynthesis						yaf	2012-07-17T04:27:51Z						biological_process											owl:Class	
GO:1902696	biolink:NamedThing	glycine catabolic process to isobutanol	The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol.	got7fsn_ti	glycine breakdown to isobutanol|glycine degradation to isobutanol|glycine catabolism to isobutanol						tb	2014-02-19T18:00:12Z			GO:1990293			biological_process											owl:Class	
GO:0044443	biolink:NamedThing	obsolete pilus part	OBSOLETE. Any constituent part of a pilus, a proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.	got7fsn_ti	fimbrial part|pilus component|fimbrium component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009289				True				cellular_component											owl:Class	
GO:0046124	biolink:NamedThing	purine deoxyribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	purine deoxyribonucleoside degradation|purine deoxyribonucleoside catabolism|purine deoxyribonucleoside breakdown													biological_process											owl:Class	
GO:0006723	biolink:NamedThing	cuticle hydrocarbon biosynthetic process	The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.	got7fsn_ti	cuticle hydrocarbon synthesis|cuticle hydrocarbon biosynthesis|cuticle hydrocarbon formation|cuticle hydrocarbon anabolism													biological_process											owl:Class	
GO:0045566	biolink:NamedThing	obsolete positive regulation of TRAIL receptor 1 biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.	got7fsn_ti	stimulation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 anabolism|up regulation of TRAIL receptor 1 biosynthetic process|activation of TRAIL receptor 1 biosynthetic process|up-regulation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 formation|positive regulation of TRAIL receptor 1 biosynthesis|positive regulation of TRAIL receptor 1 synthesis|upregulation of TRAIL receptor 1 biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0042458	biolink:NamedThing	nopaline catabolic process to proline	The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline.	got7fsn_ti	nopaline degradation to proline|nopaline breakdown to proline											MetaCyc:NOPALINEDEG-PWY		biological_process											owl:Class	
UBERON:0001054	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001597	biolink:NamedThing	obsolete apelin-like receptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	apelin-like receptor|APJ-like receptor				This term was made obsolete because the function it represents does not exist.	GO:0031704				True				molecular_function											owl:Class	
GO:0045979	biolink:NamedThing	positive regulation of nucleoside metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.	got7fsn_ti	up-regulation of nucleoside metabolic process|upregulation of nucleoside metabolic process|up regulation of nucleoside metabolic process|positive regulation of nucleoside metabolism|stimulation of nucleoside metabolic process|activation of nucleoside metabolic process													biological_process											owl:Class	
GO:1902295	biolink:NamedThing	synthesis of RNA primer involved in cell cycle DNA replication	Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication.	got7fsn_ti	replication priming involved in cell cycle DNA replication|DNA replication, synthesis of RNA primer involved in cell cycle DNA replication						jl	2013-07-09T16:06:26Z						biological_process											owl:Class	
GO:0019622	biolink:NamedThing	3-(3-hydroxy)phenylpropionate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.	got7fsn_ti	3-(3-hydroxy)phenylpropionate catabolism|3-(3-hydroxy)phenylpropionate breakdown|3-(3-hydroxy)phenylpropionate degradation											MetaCyc:HCAMHPDEG-PWY		biological_process											owl:Class	
GO:0002059	biolink:NamedThing	thymine binding	Binding to thymine.	got7fsn_ti														molecular_function											owl:Class	
GO:0052864	biolink:NamedThing	1-deoxy-D-xylulose 5-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.	got7fsn_ti	(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate breakdown|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolic process|1-deoxy-D-xylulose 5-phosphate breakdown|1-deoxy-D-xylulose 5-phosphate degradation|1-deoxy-D-xylulose 5-phosphate catabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate degradation													biological_process											owl:Class	
GO:0046337	biolink:NamedThing	phosphatidylethanolamine metabolic process	The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes.	got7fsn_ti	phosphatidylethanolamine metabolism													biological_process											owl:Class	
GO:0098767	biolink:NamedThing	obsolete meiosis II M phase	OBSOLETE. M phase during meiosis II.	got7fsn_ti					Obsoleted because added in error.	GO:0098762				True				biological_process											owl:Class	
GO:0090088	biolink:NamedThing	regulation of oligopeptide transport	Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	got7fsn_ti							tb	2009-10-23T11:23:18Z						biological_process											owl:Class	
GO:1901428	biolink:NamedThing	regulation of syringal lignin biosynthetic process	Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process.	got7fsn_ti	regulation of S-lignin biosynthetic process|regulation of syringal lignin synthesis|regulation of syringal lignin formation|regulation of syringal lignin biosynthesis|regulation of syringal lignin anabolism						tb	2012-10-01T20:13:41Z						biological_process											owl:Class	
GO:1904217	biolink:NamedThing	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	Any process that modulates the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.	got7fsn_ti	regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|regulation of phosphatidylserine synthetase activity|regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|regulation of CDP-diglyceride:serine phosphatidyltransferase activity|regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|regulation of phosphatidylserine synthase activity|regulation of PS synthase activity|regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|regulation of serine exchange enzyme				Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate		rl	2015-05-15T08:18:23Z						biological_process											owl:Class	
GO:1900966	biolink:NamedThing	negative regulation of methanophenazine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process.	got7fsn_ti	negative regulation of methanophenazine metabolism|down regulation of methanophenazine metabolism|inhibition of methanophenazine metabolic process|down-regulation of methanophenazine metabolic process|down regulation of methanophenazine metabolic process|downregulation of methanophenazine metabolism|downregulation of methanophenazine metabolic process|inhibition of methanophenazine metabolism|down-regulation of methanophenazine metabolism						tt	2012-06-14T03:55:49Z						biological_process											owl:Class	
GO:1905528	biolink:NamedThing	positive regulation of Golgi lumen acidification	Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification.	got7fsn_ti	up regulation of Golgi lumen acidification|up-regulation of Golgi lumen acidification|activation of Golgi lumen acidification|upregulation of Golgi lumen acidification						dph	2016-10-05T13:16:41Z						biological_process											owl:Class	
GO:2000022	biolink:NamedThing	regulation of jasmonic acid mediated signaling pathway	Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway.	got7fsn_ti	regulation of jasmonic acid mediated signalling pathway						tb	2010-08-05T11:24:11Z						biological_process											owl:Class	
GO:0060169	biolink:NamedThing	negative regulation of adenosine receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.	got7fsn_ti	negative regulation of adenosine receptor signalling pathway													biological_process											owl:Class	
GO:0075155	biolink:NamedThing	obsolete negative regulation of transmembrane receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont transmembrane receptor-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:2000510	biolink:NamedThing	positive regulation of dendritic cell chemotaxis	Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.	got7fsn_ti							ebc	2011-03-22T10:21:49Z						biological_process											owl:Class	
GO:0004285	biolink:NamedThing	obsolete proprotein convertase 1 activity	OBSOLETE. Catalysis of the release of protein hormones, neuropeptides and renin from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond.	got7fsn_ti	neuroendocrine convertase 1 activity|proprotein convertase 1 activity|prohormone convertase 3|prohormone convertase I activity|PC1 activity|NEC 1 activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0046075	biolink:NamedThing	dTTP metabolic process	The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate.	got7fsn_ti	dTTP metabolism													biological_process											owl:Class	
GO:0046518	biolink:NamedThing	octamethylcyclotetrasiloxane metabolic process	The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.	got7fsn_ti	octamethylcyclotetrasiloxane metabolism													biological_process											owl:Class	
GO:1901414	biolink:NamedThing	negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.	got7fsn_ti	down regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|down regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|negative regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|down regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|downregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|down regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|downregulation of tetrapyrrole formation from glycine and succinyl-CoA|inhibition of tetrapyrrole formation from glycine and succinyl-CoA|negative regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|down regulation of tetrapyrrole formation from glycine and succinyl-CoA|down-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole synthesis from glycine and succinyl-CoA|inhibition of tetrapyrrole biosynthesis from glycine and succinyl-CoA|negative regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|down-regulation of tetrapyrrole formation from glycine and succinyl-CoA|negative regulation of tetrapyrrole formation from glycine and succinyl-CoA|down-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|down-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|inhibition of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|inhibition of tetrapyrrole anabolism from glycine and succinyl-CoA|down-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|inhibition of tetrapyrrole synthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole anabolism from glycine and succinyl-CoA						tt	2012-10-01T16:28:54Z						biological_process											owl:Class	
GO:0035420	biolink:NamedThing	obsolete MAPK cascade involved in innate immune response	OBSOLETE. A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti	MAPKKK cascade involved in innate immune response	https://github.com/geneontology/go-ontology/issues/14323			This term was obsoleted because it represents a GO-CAM model.		bf	2010-03-29T01:25:59Z		True				biological_process											owl:Class	
GO:1904925	biolink:NamedThing	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization.	got7fsn_ti	up-regulation of mitophagy in response to mitochondrial depolarization|upregulation of mitophagy in response to mitochondrial depolarization|up regulation of mitophagy in response to mitochondrial depolarization|activation of mitophagy in response to mitochondrial depolarization						pad	2016-01-26T11:24:05Z						biological_process											owl:Class	
GO:0035022	biolink:NamedThing	positive regulation of Rac protein signal transduction	Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.	got7fsn_ti	activation of Rac protein signal transduction|up-regulation of Rac protein signal transduction|up regulation of Rac protein signal transduction|stimulation of Rac protein signal transduction|upregulation of Rac protein signal transduction													biological_process											owl:Class	
GO:1900702	biolink:NamedThing	negative regulation of orcinol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process.	got7fsn_ti	negative regulation of orcinol anabolism|down regulation of orcinol synthesis|inhibition of orcinol anabolism|down regulation of orcinol biosynthesis|down-regulation of orcinol formation|downregulation of orcinol synthesis|negative regulation of orcinol formation|down regulation of orcinol formation|down-regulation of orcinol biosynthesis|downregulation of orcinol formation|down regulation of orcinol biosynthetic process|down-regulation of orcinol biosynthetic process|inhibition of orcinol synthesis|inhibition of orcinol biosynthesis|downregulation of orcinol biosynthesis|negative regulation of orcinol biosynthesis|down regulation of orcinol anabolism|downregulation of orcinol anabolism|downregulation of orcinol biosynthetic process|down-regulation of orcinol synthesis|negative regulation of orcinol synthesis|inhibition of orcinol biosynthetic process|inhibition of orcinol formation|down-regulation of orcinol anabolism						di	2012-05-22T04:58:20Z						biological_process											owl:Class	
GO:0015868	biolink:NamedThing	purine ribonucleotide transport	The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0048396	biolink:NamedThing	negative regulation of intermediate mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination.	got7fsn_ti	downregulation of intermediate mesodermal cell fate determination|down-regulation of intermediate mesodermal cell fate determination|down regulation of intermediate mesodermal cell fate determination|inhibition of intermediate mesodermal cell fate determination													biological_process											owl:Class	
GO:1904222	biolink:NamedThing	positive regulation of serine C-palmitoyltransferase activity	Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity.	got7fsn_ti	positive regulation of SPT|up regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up regulation of 3-oxosphinganine synthetase activity|activation of 3-oxosphinganine synthetase activity|up-regulation of 3-oxosphinganine synthetase activity|upregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up-regulation of SPT|upregulation of SPT|positive regulation of 3-oxosphinganine synthetase activity|activation of acyl-CoA:serine C-2 acyltransferase decarboxylating|activation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up regulation of serine C-palmitoyltransferase activity|up regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|upregulation of serine C-palmitoyltransferase activity|positive regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up regulation of SPT|activation of SPT|up-regulation of serine C-palmitoyltransferase activity|activation of serine C-palmitoyltransferase activity|upregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|upregulation of 3-oxosphinganine synthetase activity|positive regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity				Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability		rl	2015-05-15T08:27:45Z						biological_process											owl:Class	
GO:0005192	biolink:NamedThing	obsolete urinary protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	urinary protein				This term was made obsolete because it describes presence in body fluids rather than an activity.					True				molecular_function											owl:Class	
GO:0035832	biolink:NamedThing	berbamunine metabolic process	The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid.	got7fsn_ti	berbamunine metabolism						bf	2011-05-04T03:11:18Z						biological_process											owl:Class	
GO:0000726	biolink:NamedThing	obsolete non-recombinational repair	OBSOLETE. A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous DNA region.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18901			This term was obsoleted because it was defined negatively, and it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0060300	biolink:NamedThing	regulation of cytokine activity	Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.	got7fsn_ti														biological_process											owl:Class	
GO:1901459	biolink:NamedThing	positive regulation of response to acetate	Any process that activates or increases the frequency, rate or extent of response to acetate.	got7fsn_ti	upregulation of response to acetate|up-regulation of response to acetate|activation of response to acetate|up regulation of response to acetate						tt	2012-10-02T14:26:34Z						biological_process											owl:Class	
CL:1000426	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001075	biolink:NamedThing	negative regulation of metanephric ureteric bud development	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development.	got7fsn_ti							yaf	2011-09-14T01:11:12Z						biological_process											owl:Class	
GO:0110099	biolink:NamedThing	negative regulation of calcium import into the mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.	got7fsn_ti							kmv	2018-02-28T00:42:06Z						biological_process											owl:Class	
GO:1905030	biolink:NamedThing	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential	Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.	got7fsn_ti	voltage gated ion channel activity involved in regulation of post-synaptic membrane potential|voltage-dependent ion channel activity involved in regulation of postsynaptic membrane potential|voltage-gated ion channel activity involved in regulation of post-synaptic membrane potential|voltage-dependent ion channel activity involved in regulation of post-synaptic membrane potential|voltage gated ion channel activity involved in regulation of postsynaptic membrane potential						dos	2016-03-04T15:51:54Z						molecular_function											owl:Class	
GO:0019440	biolink:NamedThing	tryptophan catabolic process to indole-3-acetate	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate.	got7fsn_ti	tryptophan degradation to indole-3-acetate|tryptophan catabolic process to indoleacetic acid|tryptophan breakdown to indole-3-acetate|tryptophan catabolism to indoleacetic acid|tryptophan catabolic process to IAA											MetaCyc:TRPIAACAT-PWY		biological_process											owl:Class	
GO:0003251	biolink:NamedThing	positive regulation of cell proliferation involved in heart valve morphogenesis	Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.	got7fsn_ti							dph	2009-10-13T02:07:20Z						biological_process											owl:Class	
GO:0048378	biolink:NamedThing	regulation of lateral mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification.	got7fsn_ti	regulation of lateral plate mesodermal cell fate specification													biological_process											owl:Class	
GO:1903229	biolink:NamedThing	xanthosine biosynthetic process	The chemical reactions and pathways resulting in the formation of xanthosine.	got7fsn_ti	xanthosine anabolism|xanthosine formation|xanthosine synthesis|xanthosine biosynthesis						jl	2014-07-31T09:21:58Z						biological_process											owl:Class	
GO:0046233	biolink:NamedThing	obsolete 3-hydroxyphenylacetate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.	got7fsn_ti	3-hydroxyphenylacetate anabolism|3-hydroxyphenylacetate synthesis|3-hydroxyphenylacetate formation|3-hydroxyphenylacetate biosynthesis|3-hydroxyphenylacetate biosynthetic process			GO:0019609	This term was made obsolete because 3-hydroxyphenylacetate is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1905342	biolink:NamedThing	positive regulation of protein localization to kinetochore	Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore.	got7fsn_ti	up-regulation of protein localisation to kinetochore|upregulation of protein localization to kinetochore|activation of protein localization to kinetochore|positive regulation of protein localisation to kinetochore|up regulation of condensin localization to kinetochore|upregulation of condensin localization to kinetochore|activation of protein localisation to kinetochore|positive regulation of condensin localization to kinetochore|up regulation of protein localisation to kinetochore|activation of condensin localization to kinetochore|up-regulation of protein localization to kinetochore|up-regulation of condensin localization to kinetochore|upregulation of protein localisation to kinetochore|up regulation of protein localization to kinetochore				Q9H211 in Human in PMID:22581055		es	2016-07-27T15:26:51Z						biological_process											owl:Class	
GO:1900942	biolink:NamedThing	negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.	got7fsn_ti	down-regulation of (Z)-nonadeca-1,14-diene biosynthesis|inhibition of (Z)-nonadeca-1,14-diene formation|downregulation of (Z)-nonadeca-1,14-diene formation|inhibition of (Z)-nonadeca-1,14-diene anabolism|down regulation of (Z)-nonadeca-1,14-diene anabolism|down-regulation of (Z)-nonadeca-1,14-diene anabolism|down regulation of (Z)-nonadeca-1,14-diene synthesis|down-regulation of (Z)-nonadeca-1,14-diene synthesis|downregulation of (Z)-nonadeca-1,14-diene biosynthesis|negative regulation of (Z)-nonadeca-1,14-diene synthesis|down regulation of (Z)-nonadeca-1,14-diene biosynthetic process|inhibition of (Z)-nonadeca-1,14-diene synthesis|downregulation of (Z)-nonadeca-1,14-diene anabolism|inhibition of (Z)-nonadeca-1,14-diene biosynthetic process|downregulation of (Z)-nonadeca-1,14-diene synthesis|negative regulation of (Z)-nonadeca-1,14-diene biosynthesis|down regulation of (Z)-nonadeca-1,14-diene biosynthesis|down regulation of (Z)-nonadeca-1,14-diene formation|down-regulation of (Z)-nonadeca-1,14-diene formation|downregulation of (Z)-nonadeca-1,14-diene biosynthetic process|down-regulation of (Z)-nonadeca-1,14-diene biosynthetic process|negative regulation of (Z)-nonadeca-1,14-diene formation|inhibition of (Z)-nonadeca-1,14-diene biosynthesis|negative regulation of (Z)-nonadeca-1,14-diene anabolism						tt	2012-06-14T03:17:54Z						biological_process											owl:Class	
GO:0003759	biolink:NamedThing	obsolete glycoprotein-specific chaperone activity	OBSOLETE. Assists in the correct, non-covalent assembly of glycoproteins in vivo, but is not a component of the assembled structures when performing its normal biological function. Utilizes a lectin site as a means to associate with the unfolded glycoproteins.	got7fsn_ti	glycoprotein-specific chaperone activity				This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function.	GO:0006457|GO:0044183|GO:0051082				True				molecular_function											owl:Class	
GO:0004627	biolink:NamedThing	obsolete calcium-dependent cytosolic phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	got7fsn_ti	calcium-dependent cytosolic phospholipase A2 activity				This term was made obsolete because it represents component and function information.	GO:0005829|GO:0047498				True				molecular_function											owl:Class	
GO:1903307	biolink:NamedThing	positive regulation of regulated secretory pathway	Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.	got7fsn_ti	up regulation of regulated secretory pathway|upregulation of regulated secretory pathway|up-regulation of regulated secretory pathway|activation of regulated secretory pathway				An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.		pad	2014-08-18T10:05:10Z						biological_process											owl:Class	
GO:0036115	biolink:NamedThing	fatty-acyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.	got7fsn_ti	fatty-acyl-CoA catabolism|fatty-acyl-CoA breakdown|fatty-acyl-CoA degradation						bf	2012-02-15T11:26:25Z						biological_process											owl:Class	
GO:0061106	biolink:NamedThing	negative regulation of stomach neuroendocrine cell differentiation	Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.	got7fsn_ti							dph	2010-04-29T12:23:05Z						biological_process											owl:Class	
GO:0046108	biolink:NamedThing	uridine metabolic process	The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.	got7fsn_ti	uridine metabolism													biological_process											owl:Class	
GO:0098560	biolink:NamedThing	cytoplasmic side of late endosome membrane	The side (leaflet) of the late endosome membrane that faces the cytoplasm.	got7fsn_ti	external leaflet of late endosome membrane|external side of late endosome membrane				In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane.									cellular_component											owl:Class	
GO:0015323	biolink:NamedThing	obsolete type V protein secretor activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	type V protein secretor activity				This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True				molecular_function											owl:Class	
GO:1900972	biolink:NamedThing	negative regulation of sarcinapterin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process.	got7fsn_ti	down regulation of sarcinapterin formation|inhibition of sarcinapterin anabolism|down-regulation of sarcinapterin anabolism|inhibition of sarcinapterin biosynthetic process|inhibition of sarcinapterin synthesis|negative regulation of sarcinapterin anabolism|down regulation of sarcinapterin biosynthesis|downregulation of sarcinapterin anabolism|down-regulation of sarcinapterin synthesis|negative regulation of sarcinapterin biosynthesis|negative regulation of sarcinapterin formation|downregulation of sarcinapterin biosynthesis|down regulation of sarcinapterin synthesis|downregulation of sarcinapterin biosynthetic process|down regulation of sarcinapterin anabolism|down-regulation of sarcinapterin biosynthetic process|negative regulation of sarcinapterin synthesis|downregulation of sarcinapterin synthesis|downregulation of sarcinapterin formation|inhibition of sarcinapterin formation|down regulation of sarcinapterin biosynthetic process|down-regulation of sarcinapterin biosynthesis|inhibition of sarcinapterin biosynthesis|down-regulation of sarcinapterin formation						tt	2012-06-14T04:00:06Z						biological_process											owl:Class	
GO:1900500	biolink:NamedThing	regulation of butyryl-CoA catabolic process to butyrate	Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.	got7fsn_ti	regulation of butyryl-CoA catabolism to butyrate						tt	2012-05-02T03:56:19Z						biological_process											owl:Class	
GO:1900319	biolink:NamedThing	negative regulation of methane biosynthetic process from dimethylamine	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine.	got7fsn_ti	inhibition of methane biosynthetic process from dimethylamine|downregulation of methane biosynthetic process from dimethylamine|down-regulation of methane biosynthetic process from dimethylamine|down regulation of methane biosynthetic process from dimethylamine						tt	2012-04-06T01:43:31Z						biological_process											owl:Class	
GO:0005531	biolink:NamedThing	obsolete galactose binding lectin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	galactose binding lectin				This term was made obsolete because it refers to a class of gene products.	GO:0007157|GO:0005534				True				molecular_function											owl:Class	
GO:0002646	biolink:NamedThing	regulation of central tolerance induction	Any process that modulates the frequency, rate, or extent of central tolerance induction.	got7fsn_ti														biological_process											owl:Class	
GO:1903146	biolink:NamedThing	regulation of autophagy of mitochondrion	Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.	got7fsn_ti	regulation of mitochondrion degradation						bf	2014-07-09T08:23:51Z						biological_process											owl:Class	
GO:1990364	biolink:NamedThing	obsolete response to aldehyde	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde.	got7fsn_ti	response to aldehyde				This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:18:04Z		True				biological_process											owl:Class	
GO:1900006	biolink:NamedThing	positive regulation of dendrite development	Any process that activates or increases the frequency, rate or extent of dendrite development.	got7fsn_ti	up regulation of dendrite development						hjd	2012-01-09T10:41:31Z						biological_process											owl:Class	
GO:0062044	biolink:NamedThing	negative regulation of cardiac epithelial to mesenchymal transition	Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti							dph	2018-05-10T18:21:00Z						biological_process											owl:Class	
GO:0018841	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050996	biolink:NamedThing	positive regulation of lipid catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.	got7fsn_ti	up-regulation of lipid catabolic process|positive regulation of lipid degradation|up regulation of lipid catabolic process|stimulation of lipid catabolic process|positive regulation of lipid catabolism|activation of lipid catabolic process|upregulation of lipid catabolic process|positive regulation of lipid breakdown													biological_process											owl:Class	
GO:0033762	biolink:NamedThing	response to glucagon	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.	got7fsn_ti	response to glucagon stimulus													biological_process											owl:Class	
GO:0150115	biolink:NamedThing	cell-substrate junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix.	got7fsn_ti							bc	2019-11-14T11:06:29Z						biological_process											owl:Class	
GO:1901514	biolink:NamedThing	ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out).	got7fsn_ti	lipo-chitin oligosaccharide transmembrane-transporting ATPase activity						jl	2012-10-18T11:52:55Z						molecular_function											owl:Class	
GO:0051103	biolink:NamedThing	DNA ligation involved in DNA repair	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair.	got7fsn_ti	DNA ligation during DNA repair													biological_process											owl:Class	
GO:1901897	biolink:NamedThing	regulation of relaxation of cardiac muscle	Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.	got7fsn_ti							rl	2013-02-06T21:26:58Z						biological_process											owl:Class	
GO:0045871	biolink:NamedThing	obsolete negative regulation of rhodopsin gene expression	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of rhodopsin gene expression.	got7fsn_ti	inhibition of rhodopsin gene activity|down regulation of rhodopsin gene activity|downregulation of rhodopsin gene activity|down-regulation of rhodopsin gene activity|negative regulation of rhodopsin gene activity				This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0000122				True				biological_process											owl:Class	
GO:1901149	biolink:NamedThing	salicylic acid binding	Binding to salicylic acid.	got7fsn_ti	salicylic acid receptor						dhl	2012-07-16T05:26:38Z						molecular_function											owl:Class	
GO:0006671	biolink:NamedThing	phytosphingosine metabolic process	The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids.	got7fsn_ti	phytosphingosine metabolism													biological_process											owl:Class	
PR:000013429	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17447	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051613	biolink:NamedThing	positive regulation of serotonin uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell.	got7fsn_ti	activation of serotonin uptake|upregulation of serotonin uptake|positive regulation of 5-HT uptake|positive regulation of 5-hydroxytryptamine uptake|positive regulation of serotonin import|up regulation of serotonin uptake|stimulation of serotonin uptake|positive regulation of 5HT uptake|up-regulation of serotonin uptake													biological_process											owl:Class	
GO:0031654	biolink:NamedThing	regulation of heat dissipation	Any process that modulates the rate or extent of heat dissipation.	got7fsn_ti														biological_process											owl:Class	
GO:1905391	biolink:NamedThing	regulation of protein localization to cell division site involved in cell separation after cytokinesis	Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis.	got7fsn_ti	regulation of protein localisation to cell division site involved in cytokinetic cell separation|regulation of protein localisation to cell division site involved in cell separation following cytokinesis|regulation of protein localisation to cell division site involved in mitotic cytokinetic cell separation|regulation of protein localisation to cell division site involved in cell separation after cytokinesis						vw	2016-08-22T09:40:47Z						biological_process											owl:Class	
GO:0016468	biolink:NamedThing	obsolete sodium-translocating F-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria.	got7fsn_ti	sodium-translocating F-type ATPase activity|ATP synthase				This term was made obsolete because it represents a gene product.	GO:0046962|GO:0046932				True				molecular_function											owl:Class	
CHEBI:50211	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048079	biolink:NamedThing	regulation of cuticle pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0015758	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005119	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901855	biolink:NamedThing	5,6,7,8-tetrahydrosarcinapterin biosynthetic process	The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin.	got7fsn_ti	5,6,7,8-tetrahydrosarcinapterin formation|5,6,7,8-tetrahydrosarcinapterin biosynthesis|5,6,7,8-tetrahydrosarcinapterin anabolism|5,6,7,8-tetrahydrosarcinapterin synthesis						yaf	2013-01-28T11:48:05Z						biological_process											owl:Class	
GO:0090111	biolink:NamedThing	regulation of COPII vesicle uncoating	Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released.	got7fsn_ti							tb	2009-12-06T08:34:01Z						biological_process											owl:Class	
GO:1902620	biolink:NamedThing	positive regulation of microtubule minus-end binding	Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding.	got7fsn_ti	up regulation of microtubule minus-end binding|activation of microtubule minus-end binding|up-regulation of microtubule minus-end binding|upregulation of microtubule minus-end binding						tb	2014-01-14T22:17:25Z						biological_process											owl:Class	
GO:2000652	biolink:NamedThing	regulation of secondary cell wall biogenesis	Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.	got7fsn_ti	regulation of cellulose and pectin-containing secondary cell wall biogenesis|regulation of secondary cell wall anabolism|regulation of secondary cell wall synthesis|regulation of secondary cell wall biosynthetic process|regulation of plant-type secondary cell wall biogenesis|regulation of secondary cell wall formation						dhl	2011-04-29T08:50:02Z						biological_process											owl:Class	
GO:2000459	biolink:NamedThing	negative regulation of astrocyte chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.	got7fsn_ti							bf	2011-03-04T10:54:28Z						biological_process											owl:Class	
GO:0045080	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052439	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont cell wall callose deposition	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont cell wall callose deposition				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1905111	biolink:NamedThing	positive regulation of pulmonary blood vessel remodeling	Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling.	got7fsn_ti	activation of pulmonary blood vessel remodeling|upregulation of pulmonary blood vessel remodeling|up regulation of pulmonary blood vessel remodeling|up-regulation of pulmonary blood vessel remodeling						bc	2016-04-06T13:07:42Z						biological_process											owl:Class	
GO:1904929	biolink:NamedThing	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	Any coreceptor activity that is involved in Wnt signaling pathway, planar cell polarity pathway.	got7fsn_ti	coreceptor activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt-PCP signaling pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in planar cell polarity pathway|coreceptor, soluble ligand activity involved in Wnt-JNK signaling pathway|coreceptor activity involved in non-canonical Wnt signaling pathway|coreceptor, soluble ligand activity involved in Wnt-PCP signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|Wnt/PCP co-receptor activity|coreceptor, soluble ligand activity involved in non-canonical Wnt signaling pathway|coreceptor, soluble ligand activity involved in PCP pathway|coreceptor, insoluble ligand activity involved in non-canonical Wnt signaling pathway|Wnt co-receptor activity, non-canonical signaling|coreceptor, insoluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt-JNK signaling pathway|coreceptor, insoluble ligand activity involved in PCP pathway|coreceptor activity involved in Wnt-PCP signaling pathway|coreceptor, soluble ligand activity involved in planar cell polarity pathway|coreceptor activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor activity involved in Wnt-JNK signaling pathway|coreceptor activity involved in planar cell polarity pathway|coreceptor, soluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|Wnt co-receptor, non-canonical pathway|coreceptor activity involved in PCP pathway						bf	2016-01-28T15:15:01Z						molecular_function											owl:Class	
GO:1990551	biolink:NamedThing	mitochondrial 2-oxoadipate transmembrane transport	The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:25:48Z						biological_process											owl:Class	
GO:0010083	biolink:NamedThing	regulation of vegetative meristem growth	Any process involved in maintaining the size and shape of a vegetative meristem.	got7fsn_ti	regulation of vegetative meristem size													biological_process											owl:Class	
GO:0050427	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate metabolic process	The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.	got7fsn_ti	phosphoadenosine phosphosulfate metabolism|3'-phosphoadenosine 5'-phosphosulfate metabolism|phosphoadenosine phosphosulfate metabolic process|PAPS metabolism|adenosine 3'-phosphate 5'-phosphosulfate metabolism|3'-phosphoadenosine 5'-phosphosulphate metabolic process|3'-phosphoadenylyl-sulfate metabolic process|PAPS metabolic process|adenosine 3'-phosphate 5'-phosphosulfate metabolic process|3'-phosphoadenosine 5'-phosphosulphate metabolism|3'-phosphoadenylyl-sulfate metabolism											MetaCyc:PWY-5340		biological_process											owl:Class	
CHEBI:16199	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061343	biolink:NamedThing	cell adhesion involved in heart morphogenesis	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.	got7fsn_ti							dph	2010-09-29T11:34:06Z						biological_process											owl:Class	
GO:1903854	biolink:NamedThing	negative regulation of stress response to copper ion	Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion.	got7fsn_ti	downregulation of response to copper toxicity|inhibition of stress response to copper ion|inhibition of response to copper toxicity|negative regulation of response to copper toxicity|down regulation of response to copper ion stress|downregulation of response to copper ion stress|down-regulation of response to copper ion stress|down regulation of stress response to copper ion|down-regulation of stress response to copper ion|inhibition of response to copper ion stress|down-regulation of response to copper toxicity|negative regulation of response to copper ion stress|downregulation of stress response to copper ion|down regulation of response to copper toxicity						kmv	2015-01-29T20:15:33Z						biological_process											owl:Class	
GO:0150012	biolink:NamedThing	positive regulation of neuron projection arborization	Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.	got7fsn_ti	positive regulation of neurite branching|positive regulation of neurite arborization|positive regulation of neuron projection branching						bc	2017-12-13T16:46:57Z						biological_process											owl:Class	
GO:0052718	biolink:NamedThing	tRNA-specific adenosine-34 deaminase complex	A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human.	got7fsn_ti	tRNA-A34 deaminase complex						ai	2011-08-12T11:53:26Z						cellular_component											owl:Class	
GO:1902636	biolink:NamedThing	kinociliary basal body	A ciliary basal body that is part of a kinocilium.	got7fsn_ti	microtubule basal body of kinocilium|kinocilium ciliary basal body|kinocilial basal body|cilium basal body of kinocilium|cilial basal body of kinocilium|kinocilium basal body|ciliary basal body of kinocilium						pr	2014-01-20T13:48:45Z						cellular_component											owl:Class	
GO:0062171	biolink:NamedThing	lutein biosynthetic process	The chemical reactions and pathways resulting in the formation of lutein.	got7fsn_ti	lutein biosynthesis|lutein anabolism|lutein formation						dph	2019-11-18T16:01:00Z						biological_process											owl:Class	
GO:1902853	biolink:NamedThing	negative regulation of nuclear migration during mitotic telophase	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase.	got7fsn_ti	down-regulation of nuclear migration during mitotic telophase|downregulation of nuclear migration during mitotic telophase|down regulation of nuclear migration during mitotic telophase|inhibition of nuclear migration during mitotic telophase						vw	2014-04-02T15:35:56Z						biological_process											owl:Class	
GO:1903068	biolink:NamedThing	positive regulation of protein localization to cell tip	Any process that activates or increases the frequency, rate or extent of protein localization to cell tip.	got7fsn_ti	up regulation of protein localization to cell tip|activation of protein localisation to cell tip|upregulation of protein localization to cell tip|upregulation of protein localisation to cell tip|up-regulation of protein localization to cell tip|positive regulation of protein localisation to cell tip|activation of protein localization to cell tip|up regulation of protein localisation to cell tip|up-regulation of protein localisation to cell tip						vw	2014-05-28T15:48:54Z						biological_process											owl:Class	
GO:1903167	biolink:NamedThing	regulation of pyrroline-5-carboxylate reductase activity	Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.	got7fsn_ti	regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|regulation of P5CR activity|regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|regulation of 1-pyrroline-5-carboxylate reductase activity|regulation of L-proline oxidase activity						bf	2014-07-09T19:51:19Z						biological_process											owl:Class	
GO:0097630	biolink:NamedThing	intrinsic component of omegasome membrane	The component of the omegasome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to omegasome membrane													cellular_component											owl:Class	
GO:0051948	biolink:NamedThing	negative regulation of glutamate uptake involved in transmission of nerve impulse	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.	got7fsn_ti	negative regulation of glutamate reuptake|negative regulation of glutamate uptake involved in conduction of nerve impulse|inhibition of glutamate uptake during transmission of nerve impulse|down-regulation of glutamate uptake during transmission of nerve impulse|down regulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate uptake during transmission of nerve impulse|downregulation of glutamate uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0015650	biolink:NamedThing	lactate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in).	got7fsn_ti	lactate permease|lactate:proton porter activity|lactate:hydrogen symporter activity|lactate:hydrogen porter activity													molecular_function											owl:Class	
GO:0032707	biolink:NamedThing	negative regulation of interleukin-23 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production.	got7fsn_ti	negative regulation of interleukin-23 biosynthetic process|down regulation of interleukin-23 production|inhibition of interleukin-23 production|down-regulation of interleukin-23 production|downregulation of interleukin-23 production|negative regulation of IL-23 production										GO:0045397			biological_process											owl:Class	
GO:1900286	biolink:NamedThing	negative regulation of cellotriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport.	got7fsn_ti	inhibition of cellotriose transport|down-regulation of cellotriose transport|downregulation of cellotriose transport|down regulation of cellotriose transport						tt	2012-04-05T05:56:56Z						biological_process											owl:Class	
GO:1905912	biolink:NamedThing	regulation of calcium ion export across plasma membrane	Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.	got7fsn_ti	regulation of calcium ion efflux from cell|regulation of calcium ion export from cell						rph	2017-02-07T13:20:39Z						biological_process											owl:Class	
GO:1904203	biolink:NamedThing	positive regulation of iodide transport	Any process that activates or increases the frequency, rate or extent of iodide transport.	got7fsn_ti	up-regulation of iodide transport|upregulation of iodide transport|up regulation of iodide transport|activation of iodide transport						sl	2015-05-08T15:20:09Z						biological_process											owl:Class	
GO:1904532	biolink:NamedThing	obsolete ATP-dependent microtubule motor activity, minus-end-directed involved in microtubule-based movement	OBSOLETE. Any ATP-dependent microtubule motor activity, minus-end-directed that is involved in microtubule-based movement.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2015-07-31T06:45:48Z		True				molecular_function											owl:Class	
GO:0042635	biolink:NamedThing	positive regulation of hair cycle	Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.	got7fsn_ti	upregulation of hair cycle|activation of hair cycle|up-regulation of hair cycle|stimulation of hair cycle|up regulation of hair cycle													biological_process											owl:Class	
GO:1905006	biolink:NamedThing	negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.	got7fsn_ti	downregulation of epithelial to mesenchymal transition involved in endocardial cushion formation|down regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|inhibition of epithelial to mesenchymal transition involved in endocardial cushion formation|down-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation						rl	2016-03-01T15:38:47Z						biological_process											owl:Class	
GO:1905361	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061875	biolink:NamedThing	negative regulation of hepatic stellate cell contraction	Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction.	got7fsn_ti							dph	2017-05-01T13:31:42Z						biological_process											owl:Class	
GO:0033868	biolink:NamedThing	obsolete Goodpasture-antigen-binding protein kinase activity	OBSOLETE. Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein.	got7fsn_ti	GPBPK|STK11|GPBP kinase activity|ATP:Goodpasture antigen-binding protein phosphotransferase activity|Goodpasture antigen-binding protein kinase activity				This term was made obsolete because it represents a specific gene product.					True		EC:2.7.11.9|MetaCyc:2.7.11.9-RXN		molecular_function											owl:Class	
GO:0032745	biolink:NamedThing	positive regulation of interleukin-21 production	Any process that activates or increases the frequency, rate, or extent of interleukin-21 production.	got7fsn_ti	positive regulation of IL-21 production|positive regulation of interleukin-21 biosynthetic process|stimulation of interleukin-21 production|activation of interleukin-21 production|up-regulation of interleukin-21 production|up regulation of interleukin-21 production|upregulation of interleukin-21 production										GO:0045392			biological_process											owl:Class	
GO:0033145	biolink:NamedThing	positive regulation of intracellular steroid hormone receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.	got7fsn_ti	positive regulation of steroid hormone receptor signaling pathway|positive regulation of steroid hormone receptor signalling pathway													biological_process											owl:Class	
GO:1903759	biolink:NamedThing	obsolete signal transduction involved in regulation of aerobic respiration	OBSOLETE. Any signal transduction that is involved in regulation of aerobic respiration.	got7fsn_ti	signalling pathway involved in regulation of aerobic respiration|signaling cascade involved in regulation of aerobic respiration|signaling pathway involved in regulation of aerobic respiration|signalling cascade involved in regulation of aerobic respiration				The reason for obsoletion is that this represents a GO-CAM model.		al	2014-12-18T16:37:50Z		True				biological_process											owl:Class	
GO:0044680	biolink:NamedThing	methylthiol:coenzyme M methyltransferase complex	A protein complex of two polypeptides which catalyzes the transfer of methyl group from methylthiol to coenzyme M during methanogenesis.	got7fsn_ti	methylthiol:CoM methyltransferase complex|methylthiol coenzyme M methyl transferase complex|methylthiol:coenzyme M methyl transferase complex						jl	2012-08-09T11:08:22Z						cellular_component											owl:Class	
GO:1904736	biolink:NamedThing	negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.	got7fsn_ti	downregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|inhibition of fatty acid beta-oxidation using acyl-CoA dehydrogenase|down regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|down-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase						lb	2015-10-15T08:14:57Z						biological_process											owl:Class	
GO:1905642	biolink:NamedThing	negative regulation of DNA methylation	Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.	got7fsn_ti	down-regulation of DNA methylation|downregulation of DNA methylation|inhibition of DNA methylation|down regulation of DNA methylation						bc	2016-11-04T16:43:13Z						biological_process											owl:Class	
GO:0061882	biolink:NamedThing	negative regulation of anterograde axonal transport of mitochondrion	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.	got7fsn_ti	negative regulation of anterograde axon transport of mitochondria						dph	2017-05-30T14:25:16Z						biological_process											owl:Class	
GO:0010236	biolink:NamedThing	plastoquinone biosynthetic process	The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast.	got7fsn_ti	plastoquinone synthesis|plastoquinone anabolism|plastoquinone biosynthesis|plastoquinone formation											MetaCyc:PWY-1581		biological_process											owl:Class	
GO:1902033	biolink:NamedThing	regulation of hematopoietic stem cell proliferation	Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.	got7fsn_ti	regulation of hemopoietic stem cell proliferation						ss	2013-04-02T05:13:19Z						biological_process											owl:Class	
GO:0001559	biolink:NamedThing	obsolete regulation of cell growth by detection of nuclear:cytoplasmic ratio	OBSOLETE. Any process in which the size of the nucleus with respect to the cytoplasm modulates the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.	got7fsn_ti	interpretation of nuclear:cytoplasmic ratio to regulate cell growth|detection of nuclear:cytoplasmic ratio to regulate cell growth|regulation of cell growth by sensing of nuclear:cytoplasmic ratio|regulation of cell growth by nuclear:cytoplasmic ratio				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0032878	biolink:NamedThing	regulation of establishment or maintenance of cell polarity	Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.	got7fsn_ti														biological_process											owl:Class	
GO:0060477	biolink:NamedThing	obsolete peptidyl-serine phosphorylation involved in acrosome reaction	OBSOLETE. The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14281			The reason for obsoletion is that this term does not represent a specific process.					True				biological_process											owl:Class	
GO:0030440	biolink:NamedThing	obsolete activation of MAPKK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of MAPKK during sporulation (sensu Fungi)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0052645	biolink:NamedThing	F420-0 metabolic process	The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues.	got7fsn_ti	F(420)-0 metabolic process|F420-0 metabolism|coenzyme F420-0 metabolism|coenzyme F420-0 metabolic process						ai	2010-09-22T04:11:38Z						biological_process											owl:Class	
GO:1905084	biolink:NamedThing	positive regulation of mitochondrial translational elongation	Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation.	got7fsn_ti	positive regulation of mitochondrial translation elongation|up regulation of mitochondrial translation elongation|activation of mitochondrial translational elongation|activation of mitochondrial translation elongation|up-regulation of mitochondrial translation elongation|upregulation of mitochondrial translation elongation|up regulation of mitochondrial translational elongation|up-regulation of mitochondrial translational elongation|upregulation of mitochondrial translational elongation						hjd	2016-03-25T17:37:22Z						biological_process											owl:Class	
GO:1900297	biolink:NamedThing	regulation of hexasaccharide transport	Any process that modulates the frequency, rate or extent of hexasaccharide transport.	got7fsn_ti							tt	2012-04-05T07:44:31Z						biological_process											owl:Class	
GO:0052498	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	PAMP dependent induction of symbiont innate immunity|PAMP dependent activation of symbiont innate immunity|general elicitor-dependent induction of symbiont innate immunity|pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity|MAMP dependent induction of symbiont innate immunity|general elicitor-dependent activation of symbiont innate immunity|MAMP dependent activation of symbiont innate immunity|pathogen-associated molecular pattern dependent activation by organism of symbiont innate immunity				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0100058	biolink:NamedThing	obsolete positive regulation of phenotypic switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phenotypic switching.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0050677	biolink:NamedThing	positive regulation of urothelial cell proliferation	Any process that activates or increases the rate or extent of urothelial cell proliferation.	got7fsn_ti	stimulation of urothelial cell proliferation|up-regulation of urothelial cell proliferation|up regulation of urothelial cell proliferation|activation of urothelial cell proliferation|upregulation of urothelial cell proliferation													biological_process											owl:Class	
GO:0023020	biolink:NamedThing	obsolete regulation of gene expression as a consequence of T cell signal transmission	OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a T cell signal is released and/or conveyed from one location to another.	got7fsn_ti	regulation of gene expression as a consequence of T cell signal transmission				This term was made obsolete because the meaning of the term is ambiguous.	GO:0023019		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0030824	biolink:NamedThing	obsolete negative regulation of cGMP metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cGMP.	got7fsn_ti	negative regulation of cGMP metabolism|down-regulation of cGMP metabolic process|inhibition of cGMP metabolic process|down regulation of cGMP metabolic process|downregulation of cGMP metabolic process				The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism.					True				biological_process											owl:Class	
GO:0010253	biolink:NamedThing	UDP-rhamnose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-rhamnose formation|UDP-rhamnose anabolism|UDP-rhamnose synthesis|UDP-rhamnose biosynthesis											MetaCyc:PWY-3261		biological_process											owl:Class	
GO:0097631	biolink:NamedThing	integral component of omegasome membrane	The component of the omegasome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to omegasome membrane|omegasome integral membrane protein													cellular_component											owl:Class	
GO:0030721	biolink:NamedThing	spectrosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome.	got7fsn_ti	spectrosome organisation|spectrosome organization and biogenesis													biological_process											owl:Class	
GO:2001040	biolink:NamedThing	positive regulation of cellular response to drug	Any process that activates or increases the frequency, rate or extent of cellular response to drug.	got7fsn_ti							yaf	2011-08-27T04:12:25Z						biological_process											owl:Class	
GO:0070729	biolink:NamedThing	cyclic nucleotide transport	The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.	got7fsn_ti							mah	2009-06-17T03:49:56Z						biological_process											owl:Class	
GO:1904327	biolink:NamedThing	protein localization to cytosolic proteasome complex	A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.	got7fsn_ti	protein localisation in cytosolic proteasome complex|protein localisation to cytosolic proteasome complex|protein localization in cytosolic proteasome complex						bf	2015-06-11T09:29:53Z						biological_process											owl:Class	
GO:0016583	biolink:NamedThing	obsolete nucleosome modeling	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nucleosome modeling				This term was made obsolete because it has been replaced by more specific terms.	GO:0006334				True				biological_process											owl:Class	
CHEBI:58318	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903931	biolink:NamedThing	positive regulation of pyrimidine-containing compound salvage	Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage.	got7fsn_ti	upregulation of pyrimidine-containing compound salvage|up-regulation of pyrimidine salvage|activation of pyrimidine-containing compound salvage|activation of pyrimidine salvage|up-regulation of pyrimidine-containing compound salvage|up regulation of pyrimidine salvage|up regulation of pyrimidine-containing compound salvage|positive regulation of pyrimidine salvage|upregulation of pyrimidine salvage						al	2015-02-12T14:09:15Z						biological_process											owl:Class	
GO:0006640	biolink:NamedThing	monoacylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.	got7fsn_ti	monoglyceride biosynthesis|monoacylglycerol synthesis|monoacylglycerol biosynthesis|monoglyceride biosynthetic process|monoacylglycerol anabolism|monoacylglycerol formation													biological_process											owl:Class	
GO:0043607	biolink:NamedThing	formamide biosynthetic process	The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid.	got7fsn_ti														biological_process											owl:Class	
GO:0016551	biolink:NamedThing	obsolete posttranscriptional insertion or deletion editing	OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place after transcription.	got7fsn_ti	posttranscriptional insertion/deletion editing|posttranscriptional insertion or deletion editing				This term was made obsolete because it represents two separate processes (insertion and deletion).	GO:0070705|GO:0070706				True				biological_process											owl:Class	
GO:0031058	biolink:NamedThing	positive regulation of histone modification	Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone.	got7fsn_ti	up-regulation of histone modification|stimulation of histone modification|upregulation of histone modification|activation of histone modification|up regulation of histone modification													biological_process											owl:Class	
GO:1903579	biolink:NamedThing	negative regulation of ATP metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.	got7fsn_ti	down-regulation of ATP metabolism|down-regulation of ATP metabolic process|inhibition of ATP metabolism|inhibition of ATP metabolic process|downregulation of ATP metabolic process|down regulation of ATP metabolism|negative regulation of ATP metabolism|down regulation of ATP metabolic process|downregulation of ATP metabolism						sl	2014-10-30T19:04:33Z						biological_process											owl:Class	
GO:0031117	biolink:NamedThing	positive regulation of microtubule depolymerization	Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.	got7fsn_ti	activation of microtubule depolymerization|up-regulation of microtubule depolymerization|positive regulation of microtubule disassembly|up regulation of microtubule depolymerization|positive regulation of microtubule catastrophe|microtubule destabilization|upregulation of microtubule depolymerization|stimulation of microtubule depolymerization													biological_process											owl:Class	
GO:0051398	biolink:NamedThing	obsolete N-terminal lysine aminopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of a lysine residue from the N-terminal of an oligopeptide or polypeptide chain.	got7fsn_ti	lysine aminopeptidase activity|N-terminal lysine aminopeptidase activity|lysyl aminopeptidase activity			GO:0004177	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0061067	biolink:NamedThing	negative regulation of dauer larval development	Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.	got7fsn_ti							dph	2010-03-11T01:10:23Z						biological_process											owl:Class	
GO:0030854	biolink:NamedThing	positive regulation of granulocyte differentiation	Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.	got7fsn_ti	up-regulation of granulocyte differentiation|up regulation of granulocyte differentiation|stimulation of granulocyte differentiation|upregulation of granulocyte differentiation|activation of granulocyte differentiation													biological_process											owl:Class	
GO:1902561	biolink:NamedThing	origin recognition complex assembly	The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex.	got7fsn_ti	ORC assembly|origin of replication recognition complex assembly|origin of replication recognition complex formation|ORC formation|origin recognition complex formation						mah	2013-12-10T12:11:50Z						biological_process											owl:Class	
GO:0140659	biolink:NamedThing	cytoskeletal motor regulator activity	Binds to and modulates the activity of a motor protein.	got7fsn_ti	motor activity regulator activity	https://github.com/geneontology/go-ontology/issues/21756|https://github.com/geneontology/go-ontology/issues/21627					pg	2021-06-16T11:16:00Z						molecular_function											owl:Class	
GO:1902386	biolink:NamedThing	glycyrrhetinate biosynthetic process	The chemical reactions and pathways resulting in the formation of glycyrrhetinate.	got7fsn_ti	glycyrrhetinate synthesis|glycyrrhetinate biosynthesis|glycyrrhetinate formation|glycyrrhetinate anabolism						ms	2013-09-03T12:56:19Z						biological_process											owl:Class	
GO:0009143	biolink:NamedThing	nucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	nucleoside triphosphate degradation|nucleoside triphosphate breakdown|nucleoside triphosphate catabolism													biological_process											owl:Class	
GO:1902321	biolink:NamedThing	methyl-branched fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid.	got7fsn_ti	methyl-branched fatty acid anabolism|methyl-branched fatty acid biosynthesis|methyl-branched fatty acid formation|methyl-branched fatty acid synthesis						kmv	2013-07-23T20:40:46Z						biological_process											owl:Class	
GO:0009147	biolink:NamedThing	pyrimidine nucleoside triphosphate metabolic process	The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0002056	biolink:NamedThing	cytosine binding	Binding to cytosine.	got7fsn_ti														molecular_function											owl:Class	
GO:1905204	biolink:NamedThing	negative regulation of connective tissue replacement	Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement.	got7fsn_ti	down regulation of connective tissue replacement|downregulation of connective tissue replacement|inhibition of connective tissue replacement|down-regulation of connective tissue replacement						bc	2016-05-17T09:54:27Z						biological_process											owl:Class	
GO:0090358	biolink:NamedThing	positive regulation of tryptophan metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.	got7fsn_ti	positive regulation of tryptophan metabolism						tb	2010-06-29T02:38:48Z						biological_process											owl:Class	
GO:0034255	biolink:NamedThing	regulation of urea metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.	got7fsn_ti	regulation of urea metabolism													biological_process											owl:Class	
GO:0033559	biolink:NamedThing	unsaturated fatty acid metabolic process	The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.	got7fsn_ti	unsaturated fatty acid metabolism											MetaCyc:PWY-782|MetaCyc:PWY-762		biological_process											owl:Class	
GO:1904791	biolink:NamedThing	negative regulation of shelterin complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly.	got7fsn_ti	down-regulation of Pot1-Tpz1 complex assembly|inhibition of shelterin complex formation|negative regulation of telosome assembly|downregulation of Pot1 complex assembly|inhibition of telosome assembly|negative regulation of shelterin complex formation|negative regulation of Pot1-Tpz1 complex assembly|down regulation of shelterin complex formation|down regulation of Pot1 complex assembly|downregulation of telosome assembly|down-regulation of Pot1 complex assembly|negative regulation of Pot1 complex assembly|inhibition of Pot1-Tpz1 complex assembly|inhibition of Pot1 complex assembly|down regulation of telosome assembly|down regulation of Pot1-Tpz1 complex assembly|down-regulation of telosome assembly|downregulation of Pot1-Tpz1 complex assembly|downregulation of shelterin complex formation|down-regulation of shelterin complex formation						nc	2015-11-06T16:13:11Z						biological_process											owl:Class	
GO:0031020	biolink:NamedThing	plastid mRNA editing complex	An mRNA editing complex found in a plastid.	got7fsn_ti	plastid editosome													cellular_component											owl:Class	
GO:1904282	biolink:NamedThing	regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.	got7fsn_ti	regulation of antigen processing, endogenous antigen via major histocompatibility complex class I|regulation of antigen processing, endogenous antigen via MHC class I|regulation of antigen presentation, endogenous peptide antigen|regulation of endogenous peptide antigen processing and presentation via MHC class I						rl	2015-06-04T12:05:28Z						biological_process											owl:Class	
GO:0044412	biolink:NamedThing	obsolete growth or development of symbiont in host	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of symbiont within host|growth or development of organism within host|growth or development of symbiont in host|invasive growth				This term was made obsolete because it contained a conjunction (or).	GO:0044114|GO:0051701				True				biological_process											owl:Class	
GO:2000052	biolink:NamedThing	positive regulation of non-canonical Wnt signaling pathway	Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway.	got7fsn_ti	positive regulation of non-canonical Wnt receptor signaling pathway|positive regulation of beta-catenin-independent Wnt receptor signaling pathway|positive regulation of non-canonical Wnt-activated signaling pathway|positive regulation of non-canonical Wnt receptor signalling pathway						jl	2010-08-20T01:04:25Z						biological_process											owl:Class	
GO:0120247	biolink:NamedThing	acetylenic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).	got7fsn_ti	alkyne substituted compound anabolic process|alkyne substituted compound anabolism|alkyne substituted compound synthesis|alkyne substituted compound biosynthetic process|alkyne substituted compound biosynthesis	https://github.com/geneontology/go-ontology/issues/19842					krc	2020-08-18T01:02:36Z						biological_process											owl:Class	
GO:0015372	biolink:NamedThing	obsolete glutamate/aspartate:sodium symporter activity	OBSOLETE. Catalysis of the reaction: (glutamate or aspartate)(out) + Na+(out) = (glutamate or aspartate)(in) + Na+(in).	got7fsn_ti	glutamate/aspartate:sodium symporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015183|GO:0005283|GO:0005313				True				molecular_function											owl:Class	
GO:1990870	biolink:NamedThing	obsolete protein fibril	OBSOLETE. A polymer of proteins that form a fine fiber.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-09-25T17:05:32Z		True				cellular_component											owl:Class	
GO:0018967	biolink:NamedThing	tetrachloroethylene metabolic process	The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent.	got7fsn_ti	tetrachloroethene metabolic process|tetrachloroethene metabolism|tetrachloroethylene metabolism											UM-BBD_pathwayID:tce2		biological_process											owl:Class	
GO:0002708	biolink:NamedThing	positive regulation of lymphocyte mediated immunity	Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.	got7fsn_ti	up regulation of lymphocyte mediated immunity|up-regulation of lymphocyte mediated immunity|activation of lymphocyte mediated immunity|upregulation of lymphocyte mediated immunity|stimulation of lymphocyte mediated immunity													biological_process											owl:Class	
GO:0036129	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0000122	bf	2012-03-02T10:36:39Z		True				biological_process											owl:Class	
GO:1903602	biolink:NamedThing	thermospermine catabolic process	The chemical reactions and pathways resulting in the breakdown of thermospermine.	got7fsn_ti	thermospermine degradation|thermospermine breakdown|thermospermine catabolism						tb	2014-11-12T18:48:04Z						biological_process											owl:Class	
GO:1905627	biolink:NamedThing	regulation of serotonin biosynthetic process	Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.	got7fsn_ti	regulation of serotonin anabolism|regulation of serotonin formation|regulation of serotonin biosynthesis|regulation of serotonin synthesis						pad	2016-10-31T14:26:20Z						biological_process											owl:Class	
GO:2000741	biolink:NamedThing	positive regulation of mesenchymal stem cell differentiation	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation.	got7fsn_ti							yaf	2011-06-14T02:31:34Z						biological_process											owl:Class	
GO:0062060	biolink:NamedThing	NuA4 histone acetyltransferase complex binding	Binding to a NuA4 histone acetyltransferase complex.	got7fsn_ti							dph	2018-08-31T13:51:45Z						molecular_function											owl:Class	
GO:1901089	biolink:NamedThing	acetate ester metabolic process involved in fermentation	Any acetate ester metabolic process that is involved in fermentation.	got7fsn_ti	acetate ester metabolic process during fermentation						rb	2012-07-05T11:47:17Z						biological_process											owl:Class	
GO:1905186	biolink:NamedThing	regulation of metaphase/anaphase transition of meiosis I	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I.	got7fsn_ti	regulation of meiosis I metaphase/anaphase transition|regulation of first meiotic metaphase/anaphase transition						vw	2016-05-10T16:32:03Z						biological_process											owl:Class	
GO:0051133	biolink:NamedThing	regulation of NK T cell activation	Any process that modulates the frequency, rate or extent of natural killer T cell activation.	got7fsn_ti	regulation of NK T lymphocyte activation|regulation of NKT cell activation|regulation of NK T-cell activation|regulation of natural T cell activation|regulation of NK T-lymphocyte activation|regulation of NT cell activation|regulation of natural killer T cell activation													biological_process											owl:Class	
GO:0035490	biolink:NamedThing	regulation of leukotriene production involved in inflammatory response	Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.	got7fsn_ti							bf	2010-04-26T10:49:22Z						biological_process											owl:Class	
GO:1902643	biolink:NamedThing	positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.	got7fsn_ti	up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism						di	2014-01-21T17:54:32Z						biological_process											owl:Class	
GO:0002839	biolink:NamedThing	positive regulation of immune response to tumor cell	Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.	got7fsn_ti	up regulation of immune response to tumor cell|up-regulation of immune response to tumor cell|positive regulation of immune response to tumour cell|stimulation of immune response to tumor cell|upregulation of immune response to tumor cell|activation of immune response to tumor cell													biological_process											owl:Class	
GO:0070968	biolink:NamedThing	pyrroloquinoline quinone binding	Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.	got7fsn_ti	PQQ binding						mah	2009-10-02T11:39:13Z						molecular_function											owl:Class	
GO:2001229	biolink:NamedThing	negative regulation of response to gamma radiation	Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation.	got7fsn_ti	negative regulation of response to gamma-ray photon|negative regulation of response to gamma ray						yaf	2011-11-20T04:51:14Z						biological_process											owl:Class	
GO:2000477	biolink:NamedThing	regulation of metanephric glomerular visceral epithelial cell development	Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.	got7fsn_ti	regulation of metanephric podocyte development						yaf	2011-03-09T05:16:40Z						biological_process											owl:Class	
GO:0005792	biolink:NamedThing	obsolete microsome	OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g.	got7fsn_ti	microsomal membrane|microsome				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0043231				True		Wikipedia:Microsome		cellular_component											owl:Class	
GO:0010624	biolink:NamedThing	regulation of Schwann cell proliferation	Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:0002667	biolink:NamedThing	regulation of T cell anergy	Any process that modulates the frequency, rate, or extent of T cell anergy.	got7fsn_ti	regulation of T-lymphocyte anergy|regulation of T-cell anergy|regulation of T lymphocyte anergy													biological_process											owl:Class	
GO:0008133	biolink:NamedThing	obsolete collagenase activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	collagenase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1900666	biolink:NamedThing	positive regulation of emodin biosynthetic process	Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process.	got7fsn_ti	upregulation of emodin anabolism|activation of emodin biosynthetic process|up regulation of emodin biosynthesis|upregulation of emodin synthesis|up-regulation of emodin formation|up regulation of emodin biosynthetic process|activation of emodin formation|upregulation of emodin biosynthetic process|activation of emodin anabolism|up-regulation of emodin biosynthesis|positive regulation of emodin anabolism|upregulation of emodin biosynthesis|activation of emodin biosynthesis|upregulation of emodin formation|up regulation of emodin anabolism|up regulation of emodin formation|positive regulation of emodin formation|up-regulation of emodin biosynthetic process|positive regulation of emodin biosynthesis|up-regulation of emodin anabolism|up-regulation of emodin synthesis|positive regulation of emodin synthesis|up regulation of emodin synthesis|activation of emodin synthesis						di	2012-05-22T04:15:06Z						biological_process											owl:Class	
GO:0100030	biolink:NamedThing	obsolete regulation of histone acetylation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone acetylation.	got7fsn_ti					This term was obsoleted because it describes a process that does not exist.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0020037	biolink:NamedThing	heme binding	Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.	got7fsn_ti	haem binding													molecular_function											owl:Class	
GO:2000853	biolink:NamedThing	negative regulation of corticosterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion.	got7fsn_ti							bf	2011-07-26T08:45:43Z						biological_process											owl:Class	
GO:0072484	biolink:NamedThing	obsolete detection of stimulus involved in spindle assembly checkpoint	OBSOLETE. The series of events in which information about spindle assembly is received and converted into a molecular signal, contributing to a spindle assembly checkpoint.	got7fsn_ti	sensing involved in spindle assembly checkpoint|spindle assembly checkpoint sensor process|spindle assembly checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T12:19:16Z		True				biological_process											owl:Class	
GO:0036109	biolink:NamedThing	alpha-linolenic acid metabolic process	The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.	got7fsn_ti	alpha-linolenic acid metabolism|ALA metabolism						bf	2012-02-15T10:16:42Z				Wikipedia:Linoleic_acid		biological_process											owl:Class	
GO:2000461	biolink:NamedThing	obsolete negative regulation of eukaryotic cell surface binding	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic cell surface binding.	got7fsn_ti	negative regulation of eukaryotic cell surface binding				This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion.	GO:1900121|GO:0031347	yaf	2011-03-04T12:00:26Z		True				biological_process											owl:Class	
GO:0036248	biolink:NamedThing	phytochelatin 4 import into vacuole	The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.	got7fsn_ti	PC4 import into vacuole						bf	2012-05-31T11:12:08Z						biological_process											owl:Class	
GO:0140660	biolink:NamedThing	cytoskeletal motor activator activity	Binds to and increases the activity of a motor protein.	got7fsn_ti	motor activity activator activity	https://github.com/geneontology/go-ontology/issues/21756|https://github.com/geneontology/go-ontology/issues/21627					pg	2021-06-16T11:18:55Z						molecular_function											owl:Class	
GO:1900950	biolink:NamedThing	regulation of 18-methylnonadec-1-ene biosynthetic process	Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.	got7fsn_ti	regulation of 18-methylnonadec-1-ene anabolism|regulation of 18-methylnonadec-1-ene formation|regulation of 18-methylnonadec-1-ene synthesis|regulation of 18-methylnonadec-1-ene biosynthesis						tt	2012-06-14T03:23:34Z						biological_process											owl:Class	
GO:0051159	biolink:NamedThing	D-arabitol catabolic process	The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.	got7fsn_ti	D-arabitol degradation|D-arabitol breakdown|D-arabitol catabolism													biological_process											owl:Class	
GO:1904976	biolink:NamedThing	cellular response to bleomycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.	got7fsn_ti							mah	2016-02-18T15:21:31Z						biological_process											owl:Class	
UBERON:0005333	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903065	biolink:NamedThing	obsolete protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape	OBSOLETE. Any protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape.	got7fsn_ti	protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape				This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2014-05-28T15:29:27Z		True				biological_process											owl:Class	
GO:0010815	biolink:NamedThing	bradykinin catabolic process	The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.	got7fsn_ti														biological_process											owl:Class	
GO:0030300	biolink:NamedThing	regulation of intestinal cholesterol absorption	Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption.	got7fsn_ti														biological_process											owl:Class	
GO:1904797	biolink:NamedThing	negative regulation of core promoter binding	Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding.	got7fsn_ti	down-regulation of core promoter binding|downregulation of core promoter binding|down regulation of core promoter binding|inhibition of core promoter binding						nc	2015-11-09T12:32:31Z						biological_process											owl:Class	
GO:0010666	biolink:NamedThing	positive regulation of cardiac muscle cell apoptotic process	Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	got7fsn_ti	positive regulation of cardiac muscle cell apoptosis													biological_process											owl:Class	
GO:0150079	biolink:NamedThing	negative regulation of neuroinflammatory response	Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.	got7fsn_ti							bc	2018-07-26T12:38:08Z						biological_process											owl:Class	
GO:1905841	biolink:NamedThing	response to oxidopamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.	got7fsn_ti							pr	2017-01-19T09:49:03Z						biological_process											owl:Class	
GO:1900776	biolink:NamedThing	fumiquinazoline A metabolic process	The chemical reactions and pathways involving fumiquinazoline A.	got7fsn_ti	fumiquinazoline A metabolism						di	2012-06-04T09:29:58Z						biological_process											owl:Class	
SO:0000587	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003155	biolink:NamedThing	BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to the determination of lateral mesoderm left/right asymmetry.	got7fsn_ti	BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry						tb	2009-09-24T05:42:17Z						biological_process											owl:Class	
GO:0001511	biolink:NamedThing	obsolete fibrillin	OBSOLETE. Large glycoprotein that is a calcium binding component of connective tissue microfibrils containing 34 six-cysteine (EGF-like) repeats and five eight-cysteine (TGFbeta-1 binding protein-like) repeats. Defects associated with Marfan syndrome.	got7fsn_ti	fibrillin				This term was made obsolete because it represents a gene product.	GO:0001527|GO:0005509				True				molecular_function											owl:Class	
GO:0046417	biolink:NamedThing	chorismate metabolic process	The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid.	got7fsn_ti	chorismate metabolism													biological_process											owl:Class	
GO:1904799	biolink:NamedThing	regulation of neuron remodeling	Any process that modulates the frequency, rate or extent of neuron remodeling.	got7fsn_ti	regulation of neuronal remodeling|regulation of axon pruning				cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype)		es	2015-11-09T13:46:52Z						biological_process											owl:Class	
GO:1905849	biolink:NamedThing	negative regulation of forward locomotion	Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion.	got7fsn_ti	downregulation of forward locomotion|inhibition of forward locomotion|down-regulation of forward locomotion|down regulation of forward locomotion						rz	2017-01-23T11:03:55Z						biological_process											owl:Class	
GO:1903624	biolink:NamedThing	regulation of DNA catabolic process	Any process that modulates the frequency, rate or extent of DNA catabolic process.	got7fsn_ti	regulation of DNA catabolism|regulation of DNA degradation|regulation of DNA breakdown						sl	2014-11-19T22:36:35Z						biological_process											owl:Class	
GO:1904326	biolink:NamedThing	negative regulation of circadian sleep/wake cycle, wakefulness	Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness.	got7fsn_ti	downregulation of circadian sleep/wake cycle, wakefulness|down-regulation of circadian sleep/wake cycle, wakefulness|inhibition of circadian sleep/wake cycle, wakefulness|down regulation of circadian sleep/wake cycle, wakefulness						sl	2015-06-10T20:18:45Z						biological_process											owl:Class	
GO:0043483	biolink:NamedThing	anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light	The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus.	got7fsn_ti	anthocyanin biosynthetic process during anthocyanin accumulation in response to UV light|anthocyanin biosynthesis during anthocyanin accumulation in tissues in response to UV light stimulus|anthocyanin biosynthetic process during anthocyanin accumulation in tissues in response to UV light stimulus													biological_process											owl:Class	
GO:1905793	biolink:NamedThing	protein localization to pericentriolar material	A process in which a protein is transported to, or maintained in, a location within a pericentriolar material.	got7fsn_ti	protein localization in pericentriolar material|protein localisation to pericentriolar material|protein localisation in pericentriolar material						ha	2017-01-10T11:10:37Z						biological_process											owl:Class	
GO:2000838	biolink:NamedThing	negative regulation of androstenedione secretion	Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion.	got7fsn_ti	negative regulation of androst-4-ene-3,17-dione secretion						bf	2011-07-26T08:40:40Z						biological_process											owl:Class	
GO:0070958	biolink:NamedThing	negative regulation of neutrophil mediated killing of gram-positive bacterium	Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.	got7fsn_ti	downregulation of neutrophil mediated killing of gram-positive bacterium|inhibition of neutrophil mediated killing of gram-positive bacterium|down regulation of neutrophil mediated killing of gram-positive bacterium|down-regulation of neutrophil mediated killing of gram-positive bacterium						mah	2009-10-01T02:20:17Z						biological_process											owl:Class	
CHEBI:36141	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904859	biolink:NamedThing	positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.	got7fsn_ti	upregulation of endothelial cell chemotaxis to vascular endothelial growth factor|up regulation of endothelial cell chemotaxis to vascular endothelial growth factor|up-regulation of endothelial cell chemotaxis to vascular endothelial growth factor|activation of endothelial cell chemotaxis to vascular endothelial growth factor						rph	2015-12-16T11:48:00Z						biological_process											owl:Class	
CHEBI:8005	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042353	biolink:NamedThing	fucose biosynthetic process	The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose).	got7fsn_ti	fucose anabolism|fucose synthesis|fucose formation|fucose biosynthesis													biological_process											owl:Class	
GO:0106113	biolink:NamedThing	positive regulation of mitotic cohesin ssDNA (lagging strand) loading	Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.	got7fsn_ti							hjd	2018-04-18T14:46:03Z						biological_process											owl:Class	
GO:0001687	biolink:NamedThing	obsolete cytoplasmic dynein heavy chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytoplasmic dynein heavy chain			GO:0005868	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:1903535	biolink:NamedThing	negative regulation of lactose biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process.	got7fsn_ti	down-regulation of lactose synthesis|down-regulation of lactose biosynthesis|inhibition of lactose biosynthetic process|down regulation of lactose synthesis|downregulation of lactose synthesis|down-regulation of lactose formation|down regulation of lactose biosynthetic process|inhibition of lactose anabolism|downregulation of lactose formation|inhibition of lactose formation|negative regulation of lactose formation|negative regulation of lactose anabolism|down-regulation of lactose anabolism|down regulation of lactose biosynthesis|down regulation of lactose anabolism|downregulation of lactose anabolism|downregulation of lactose biosynthesis|negative regulation of lactose biosynthesis|inhibition of lactose biosynthesis|downregulation of lactose biosynthetic process|negative regulation of lactose synthesis|down-regulation of lactose biosynthetic process|inhibition of lactose synthesis|down regulation of lactose formation						mr	2014-10-08T16:26:14Z						biological_process											owl:Class	
GO:1903787	biolink:NamedThing	negative regulation of glutathione biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process.	got7fsn_ti	down-regulation of glutathione biosynthesis|downregulation of glutathione synthesis|down-regulation of glutathione anabolism|downregulation of glutathione biosynthesis|down regulation of glutathione formation|inhibition of glutathione anabolism|down regulation of glutathione biosynthetic process|negative regulation of glutathione formation|downregulation of glutathione anabolism|down-regulation of glutathione synthesis|down regulation of glutathione anabolism|downregulation of glutathione biosynthetic process|down-regulation of glutathione biosynthetic process|inhibition of glutathione formation|down-regulation of glutathione formation|downregulation of glutathione formation|negative regulation of glutathione anabolism|inhibition of glutathione biosynthetic process|inhibition of glutathione biosynthesis|negative regulation of glutathione synthesis|inhibition of glutathione synthesis|down regulation of glutathione biosynthesis|negative regulation of glutathione biosynthesis|down regulation of glutathione synthesis						bf	2015-01-08T17:14:59Z						biological_process											owl:Class	
GO:1904291	biolink:NamedThing	positive regulation of mitotic DNA damage checkpoint	Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint.	got7fsn_ti	up-regulation of mitotic DNA damage checkpoint|upregulation of mitotic DNA damage checkpoint|activation of mitotic DNA damage checkpoint|up regulation of mitotic DNA damage checkpoint						kmv	2015-06-09T13:03:23Z						biological_process											owl:Class	
GO:0046022	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.	got7fsn_ti	up-regulation of transcription from RNA polymerase II promoter during mitosis|positive regulation of transcription from Pol II promoter during mitosis|stimulation of transcription from RNA polymerase II promoter during mitosis|activation of transcription from RNA polymerase II promoter during mitosis|up regulation of transcription from RNA polymerase II promoter during mitosis|positive regulation of transcription from RNA polymerase II promoter, mitotic|mitotic activation of transcription from Pol II promoter|upregulation of transcription from RNA polymerase II promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0045944				True				biological_process											owl:Class	
GO:1901490	biolink:NamedThing	regulation of lymphangiogenesis	Any process that modulates the frequency, rate or extent of lymphangiogenesis.	got7fsn_ti	regulation of lymph vessel formation						dph	2012-10-15T13:08:17Z						biological_process											owl:Class	
GO:0070835	biolink:NamedThing	chromium ion transmembrane transporter activity	Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.	got7fsn_ti							mah	2009-07-30T03:04:09Z						molecular_function											owl:Class	
GO:1901322	biolink:NamedThing	response to chloramphenicol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.	got7fsn_ti							tb	2012-08-30T00:01:07Z						biological_process											owl:Class	
GO:0002028	biolink:NamedThing	regulation of sodium ion transport	Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of Na+ transport|regulation of sodium transport													biological_process											owl:Class	
GO:1903797	biolink:NamedThing	positive regulation of inorganic anion transmembrane transport	Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport.	got7fsn_ti	up regulation of inorganic anion membrane transport|positive regulation of inorganic anion membrane transport|up-regulation of inorganic anion transmembrane transport|activation of transmembrane inorganic anion transport|upregulation of inorganic anion transmembrane transport|positive regulation of transmembrane inorganic anion transport|activation of inorganic anion membrane transport|up-regulation of transmembrane inorganic anion transport|upregulation of inorganic anion membrane transport|activation of inorganic anion transmembrane transport|up regulation of inorganic anion transmembrane transport|up-regulation of inorganic anion membrane transport|upregulation of transmembrane inorganic anion transport|up regulation of transmembrane inorganic anion transport						sl	2015-01-14T21:45:08Z						biological_process											owl:Class	
GO:0009483	biolink:NamedThing	obsolete caa3-type cytochrome c oxidase	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.	got7fsn_ti	caa3-type cytochrome c oxidase			GO:0004129	This term was made obsolete because it describes a class of gene products rather than a molecular function.					True				molecular_function											owl:Class	
GO:0035204	biolink:NamedThing	negative regulation of lamellocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.	got7fsn_ti	down-regulation of lamellocyte differentiation|downregulation of lamellocyte differentiation|inhibition of lamellocyte differentiation|down regulation of lamellocyte differentiation													biological_process											owl:Class	
GO:2000615	biolink:NamedThing	regulation of histone H3-K9 acetylation	Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation.	got7fsn_ti	regulation of histone H3 acetylation at K9|regulation of histone H3K9 acetylation						vk	2011-04-18T03:15:59Z						biological_process											owl:Class	
GO:0061151	biolink:NamedThing	BMP signaling pathway involved in renal system segmentation	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system.	got7fsn_ti	BMP signalling pathway involved in renal system segmentation						dph	2010-06-02T09:29:43Z						biological_process											owl:Class	
GO:0035569	biolink:NamedThing	obsolete N-terminal peptidyl-proline trimethylation	OBSOLETE. The trimethylation of the N-terminal proline of proteins to form the derivative N,N,N-trimethylproline.	got7fsn_ti	N-terminal peptidyl-proline trimethylation				This term was made obsolete because N-terminal proline residues cannot be trimethylated.		bf	2010-08-06T01:55:19Z		True				biological_process											owl:Class	
GO:0001011	biolink:NamedThing	obsolete transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting	OBSOLETE. Binding to a specific DNA sequence and recruiting RNA polymerase to the DNA in order to form the preinitiation complex (PIC).	got7fsn_ti	sequence-specific DNA binding RNA polymerase recruiting transcription factor activity				This term was obsoleted because it was not clearly defined and usage has been inconsistent.	GO:0140223	krc	2010-08-18T06:49:16Z		True				molecular_function											owl:Class	
GO:0060556	biolink:NamedThing	regulation of vitamin D biosynthetic process	Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	got7fsn_ti							dph	2009-04-13T02:42:15Z						biological_process											owl:Class	
GO:0150189	biolink:NamedThing	regulation of interleukin-32 production	Any process that modulates the frequency, rate or extent of interleukin-32 production.	got7fsn_ti	regulation of interleukin-32 secretion|regulation of interleukin-32 biosynthetic process						bc	2020-02-21T10:28:36Z			GO:0150192			biological_process											owl:Class	
GO:1900744	biolink:NamedThing	regulation of p38MAPK cascade	Any process that modulates the frequency, rate or extent of p38MAPK cascade.	got7fsn_ti	regulation of p38 MAPK cascade|regulation of p38 cascade						pm	2012-05-28T02:40:14Z						biological_process											owl:Class	
GO:1904908	biolink:NamedThing	negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.	got7fsn_ti	down-regulation of maintenance of sister chromatin cohesion at telomere at mitosis|inhibition of maintenance of mitotic sister chromatin cohesion at telomere|down-regulation of maintenance of telomeric mitotic sister chromatin cohesion|inhibition of maintenance of telomeric mitotic sister chromatin cohesion|down-regulation of maintenance of mitotic sister chromatin cohesion at telomere|down regulation of maintenance of mitotic sister chromatid cohesion, telomeric|down-regulation of maintenance of mitotic sister chromatid cohesion, telomeric|inhibition of maintenance of mitotic sister chromatid cohesion, telomeric|downregulation of maintenance of mitotic sister chromatid cohesion, telomeric|inhibition of maintenance of sister chromatin cohesion at telomere at mitosis|negative regulation of maintenance of telomeric mitotic sister chromatin cohesion|negative regulation of maintenance of sister chromatin cohesion at telomere at mitosis|down regulation of maintenance of mitotic sister chromatin cohesion at telomere|negative regulation of maintenance of mitotic sister chromatin cohesion at telomere|downregulation of maintenance of sister chromatin cohesion at telomere at mitosis|downregulation of maintenance of mitotic sister chromatin cohesion at telomere|downregulation of maintenance of telomeric mitotic sister chromatin cohesion|down regulation of maintenance of sister chromatin cohesion at telomere at mitosis|down regulation of maintenance of telomeric mitotic sister chromatin cohesion						rph	2016-01-19T10:30:36Z						biological_process											owl:Class	
GO:0016470	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006003	biolink:NamedThing	fructose 2,6-bisphosphate metabolic process	The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.	got7fsn_ti	fructose 2,6-bisphosphate metabolism													biological_process											owl:Class	
GO:0070813	biolink:NamedThing	hydrogen sulfide metabolic process	The chemical reactions and pathways involving hydrogen sulfide, H2S.	got7fsn_ti	hydrogen sulphide metabolic process|hydrogen sulphide metabolism|hydrogen sulfide metabolism						mah	2009-07-09T10:37:32Z						biological_process											owl:Class	
GO:0014007	biolink:NamedThing	negative regulation of microglia differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.	got7fsn_ti	downregulation of microglia differentiation|inhibition of microglia differentiation|down regulation of microglia differentiation|negative regulation of microglial cell differentiation|down-regulation of microglia differentiation													biological_process											owl:Class	
GO:2000020	biolink:NamedThing	positive regulation of male gonad development	Any process that activates or increases the frequency, rate or extent of male gonad development.	got7fsn_ti	positive regulation of testicular development|positive regulation of testis development						jl	2010-07-15T03:29:13Z						biological_process											owl:Class	
GO:1905540	biolink:NamedThing	interleukin-7 receptor complex	A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors.	got7fsn_ti	IL-7 receptor complex|IL7-receptor complex|IL-7-receptor complex|IL7 receptor complex				An example of this is IL7R in human (P16871) in PMID:19141282 (inferred from direct assay).		bhm	2016-10-10T07:44:05Z						cellular_component											owl:Class	
GO:0062057	biolink:NamedThing	L-aspartate:fumarate antiporter activity	Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out).	got7fsn_ti							dph	2018-08-09T14:25:45Z						molecular_function											owl:Class	
GO:1900839	biolink:NamedThing	positive regulation of fumigaclavine C biosynthetic process	Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process.	got7fsn_ti	up regulation of fumigaclavine C biosynthetic process|upregulation of fumigaclavine C biosynthetic process|up-regulation of fumigaclavine C biosynthetic process						di	2012-06-07T09:36:52Z						biological_process											owl:Class	
GO:1903244	biolink:NamedThing	positive regulation of cardiac muscle hypertrophy in response to stress	Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.	got7fsn_ti	upregulation of cardiac muscle hypertrophy in response to stress|up regulation of cardiac muscle hypertrophy in response to stress|up-regulation of cardiac muscle hypertrophy in response to stress|activation of cardiac muscle hypertrophy in response to stress						rl	2014-08-01T16:31:48Z						biological_process											owl:Class	
GO:1901413	biolink:NamedThing	regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.	got7fsn_ti	regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|regulation of tetrapyrrole formation from glycine and succinyl-CoA						tt	2012-10-01T16:27:43Z						biological_process											owl:Class	
GO:0002613	biolink:NamedThing	regulation of monocyte antigen processing and presentation	Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:0044008	biolink:NamedThing	obsolete dissemination or transmission of symbiont from host by vector	OBSOLETE. The movement of an organism from one host to another (or another place in the environment) by means of a third organism (often an insect or other animal). The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	dissemination or transmission of organism from host by vector				This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.					True				biological_process											owl:Class	
GO:1903479	biolink:NamedThing	mitotic actomyosin contractile ring assembly actin filament organization	Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti	actin filament organisation involved in mitotic actomyosin contractile ring assembly|actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|actin filament organization involved in mitotic actomyosin contractile ring assembly						vw	2014-09-23T15:03:19Z						biological_process											owl:Class	
GO:2000503	biolink:NamedThing	positive regulation of natural killer cell chemotaxis	Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis.	got7fsn_ti							bf	2011-03-21T10:09:38Z						biological_process											owl:Class	
GO:0009462	biolink:NamedThing	obsolete cytochrome d	OBSOLETE. A cytochrome in which the prosthetic group is a tetrapyrrolic chelate of iron in which the degree of conjugation of double bonds is less than in porphyrin. This definition would appear to include siroheme proteins (e.g. nitrite and sulfite reductases), but these are not cytochromes.	got7fsn_ti	cytochrome d				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0030191	biolink:NamedThing	obsolete Hsp70/Hsc70 protein inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of chaperones of the Hsp70/Hsc70 class.	got7fsn_ti	Hsp70/Hsc70 protein inhibitor activity				This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70/Hsc70 protein activity'.	GO:0051082|GO:0051787|GO:0006457				True				molecular_function											owl:Class	
GO:0000312	biolink:NamedThing	plastid small ribosomal subunit	The smaller of the two subunits of a plastid ribosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0034883	biolink:NamedThing	obsolete isonicotinate reductase activity	OBSOLETE. Catalysis of the reaction: isonicotinate + 2 H+ + 2 e- = 1,4-dihydroisonicotinate.	got7fsn_ti	isonicotinate reductase activity				This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.	GO:0016627				True				molecular_function											owl:Class	
GO:1905672	biolink:NamedThing	negative regulation of lysosome organization	Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.	got7fsn_ti	downregulation of lysosome organization and biogenesis|down regulation of lysosome organization and biogenesis|inhibition of lysosome organization|down regulation of lysosome organisation|down-regulation of lysosome organisation|negative regulation of lysosome organization and biogenesis|downregulation of lysosome organisation|downregulation of lysosome organization|down regulation of lysosome organization|down-regulation of lysosome organization and biogenesis|inhibition of lysosome organization and biogenesis|down-regulation of lysosome organization|negative regulation of lysosome organisation|inhibition of lysosome organisation						sl	2016-11-11T22:01:12Z						biological_process											owl:Class	
GO:0014709	biolink:NamedThing	positive regulation of somitomeric trunk muscle development	Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	got7fsn_ti														biological_process											owl:Class	
GO:1904268	biolink:NamedThing	positive regulation of Schwann cell chemotaxis	Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis.	got7fsn_ti	activation of Schwann cell chemotaxis|up regulation of Schwann cell chemotaxis|upregulation of Schwann cell chemotaxis|up-regulation of Schwann cell chemotaxis						sl	2015-05-28T17:47:55Z						biological_process											owl:Class	
GO:1900914	biolink:NamedThing	regulation of octadecene biosynthetic process	Any process that modulates the frequency, rate or extent of octadecene biosynthetic process.	got7fsn_ti	regulation of 1-octadecene biosynthetic process|regulation of octadecene formation|regulation of octadecene synthesis|regulation of octadecene biosynthesis|regulation of octadecene anabolism						tt	2012-06-13T04:24:24Z						biological_process											owl:Class	
GO:2000207	biolink:NamedThing	negative regulation of ribosomal small subunit export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus.	got7fsn_ti	negative regulation of 40S ribosomal subunit export from nucleus|negative regulation of 30S ribosomal subunit export from nucleus|negative regulation of ribosomal small subunit transport from nucleus to cytoplasm|negative regulation of ribosomal small subunit export from cell nucleus|negative regulation of ribosomal small subunit-nucleus export|negative regulation of ribosomal small subunit export out of nucleus						mah	2010-10-26T10:54:14Z						biological_process											owl:Class	
GO:0002620	biolink:NamedThing	negative regulation of non-professional antigen presenting cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.	got7fsn_ti	down-regulation of non-professional antigen presenting cell antigen processing and presentation|down regulation of non-professional antigen presenting cell antigen processing and presentation|inhibition of non-professional antigen presenting cell antigen processing and presentation|downregulation of non-professional antigen presenting cell antigen processing and presentation													biological_process											owl:Class	
GO:0052432	biolink:NamedThing	obsolete modulation by organism of symbiont apoptosis	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont apoptosis|modulation by organism of symbiont apoptotic programmed cell death				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0004230	biolink:NamedThing	obsolete glutamyl aminopeptidase activity	OBSOLETE. Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide.	got7fsn_ti	glutamyl peptidase activity|membrane aminopeptidase II|angiotensinase A2|glutamyl aminopeptidase activity|L-aspartate aminopeptidase activity|antigen BP-1/6C3 of mouse B lymphocytes|aminopeptidase A|Ca2+-activated glutamate aminopeptidase activity|angiotensinase A|aspartate aminopeptidase activity				This term was made obsolete because it represents a gene product.	GO:0008235|GO:0004177				True		EC:3.4.11.7|MetaCyc:3.4.11.7-RXN		molecular_function											owl:Class	
GO:1904579	biolink:NamedThing	cellular response to thapsigargin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus.	got7fsn_ti							sl	2015-08-19T18:06:28Z						biological_process											owl:Class	
GO:2000987	biolink:NamedThing	positive regulation of behavioral fear response	Any process that activates or increases the frequency, rate or extent of behavioral fear response.	got7fsn_ti	positive regulation of behavioural fear response						yaf	2011-08-08T09:16:39Z						biological_process											owl:Class	
GO:0052393	biolink:NamedThing	obsolete induction by host of symbiont defense response	OBSOLETE. The activation by an organism of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation of symbiont defense response				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response.					True				biological_process											owl:Class	
GO:1902857	biolink:NamedThing	positive regulation of non-motile cilium assembly	Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.	got7fsn_ti	activation of sensory cilium assembly|up regulation of nonmotile primary cilia assembly|positive regulation of sensory cilium biogenesis|upregulation of immotile primary cilium assembly|upregulation of sensory cilium biogenesis|upregulation of sensory cilium assembly|up-regulation of immotile primary cilium assembly|activation of sensory cilium biogenesis|upregulation of nonmotile primary cilia assembly|up regulation of sensory cilium assembly|up-regulation of sensory cilium biogenesis|up regulation of immotile primary cilium assembly|upregulation of nonmotile primary cilium assembly|positive regulation of nonmotile primary cilium assembly|activation of nonmotile primary cilia assembly|up regulation of sensory cilium biogenesis|up-regulation of nonmotile primary cilia assembly|up-regulation of nonmotile primary cilium assembly|up-regulation of sensory cilium assembly|positive regulation of sensory cilium assembly|positive regulation of nonmotile primary cilia assembly|activation of nonmotile primary cilium assembly|positive regulation of immotile primary cilium assembly|up regulation of nonmotile primary cilium assembly|activation of immotile primary cilium assembly						kmv	2014-04-02T15:42:31Z						biological_process											owl:Class	
GO:0003123	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030573	biolink:NamedThing	bile acid catabolic process	The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.	got7fsn_ti	bile acid 7alpha-dehydroxylation pathway|bile acid degradation|cholate catabolic process|bile acid catabolism|bile acid breakdown										GO:0019613	MetaCyc:7ALPHADEHYDROX-PWY		biological_process											owl:Class	
GO:0098563	biolink:NamedThing	intrinsic component of synaptic vesicle membrane	The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:1903419	biolink:NamedThing	protein localization to cortical endoplasmic reticulum	A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum.	got7fsn_ti	protein localization to cortical ER|protein localisation in cortical endoplasmic reticulum|protein localization in cortical endoplasmic reticulum|protein localisation to cortical endoplasmic reticulum						mah	2014-09-08T16:03:28Z						biological_process											owl:Class	
GO:0015147	biolink:NamedThing	L-arabinose transmembrane transporter activity	Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.	got7fsn_ti	L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity													molecular_function											owl:Class	
GO:1904665	biolink:NamedThing	positive regulation of N-terminal peptidyl-methionine acetylation	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.	got7fsn_ti							vw	2015-09-07T19:19:02Z						biological_process											owl:Class	
GO:1905871	biolink:NamedThing	regulation of protein localization to cell leading edge	Any process that modulates the frequency, rate or extent of protein localization to cell leading edge.	got7fsn_ti	regulation of protein localisation in cell leading edge|regulation of protein localisation to cell leading edge|regulation of protein localization in cell leading edge						sl	2017-01-27T19:34:55Z						biological_process											owl:Class	
GO:0015449	biolink:NamedThing	obsolete type IV protein (DNA-protein) secretor activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	type IV protein (DNA-protein) secretor activity				This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True				molecular_function											owl:Class	
GO:1905895	biolink:NamedThing	negative regulation of cellular response to tunicamycin	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to tunicamycin.	got7fsn_ti	downregulation of cellular response to tunicamycin|down regulation of cellular response to tunicamycin|down-regulation of cellular response to tunicamycin|inhibition of cellular response to tunicamycin						bc	2017-02-01T11:36:42Z						biological_process											owl:Class	
GO:1901092	biolink:NamedThing	positive regulation of protein tetramerization	Any process that activates or increases the frequency, rate or extent of protein tetramerization.	got7fsn_ti	activation of protein tetramer biosynthesis|activation of protein tetramerization|up-regulation of protein tetramer formation|positive regulation of protein tetramer biosynthesis|up-regulation of protein tetramerization|activation of protein tetramer formation|up regulation of protein tetramer formation|up regulation of protein tetramer biosynthetic process|upregulation of protein tetramer formation|up regulation of protein tetramer assembly|upregulation of protein tetramer biosynthesis|positive regulation of protein tetramer biosynthetic process|activation of protein tetramer assembly|up regulation of protein tetramer biosynthesis|activation of protein tetramer biosynthetic process|up regulation of protein tetramerization|upregulation of protein tetramer assembly|positive regulation of protein tetramer formation|up-regulation of protein tetramer biosynthesis|upregulation of protein tetramerization|positive regulation of protein tetramer assembly|up-regulation of protein tetramer assembly|upregulation of protein tetramer biosynthetic process|up-regulation of protein tetramer biosynthetic process						pm	2012-07-06T12:51:32Z						biological_process											owl:Class	
GO:0075089	biolink:NamedThing	obsolete negative regulation by host of symbiont G protein-coupled receptor signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by host of symbiont G-protein coupled receptor protein signal transduction				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0052177	biolink:NamedThing	obsolete metabolism by symbiont of host xylan	OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:1901417	biolink:NamedThing	negative regulation of response to ethanol	Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol.	got7fsn_ti	down-regulation of response to ethanol|inhibition of response to ethanol|down regulation of response to ethanol|downregulation of response to ethanol						tt	2012-10-01T16:49:33Z						biological_process											owl:Class	
GO:0032273	biolink:NamedThing	positive regulation of protein polymerization	Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.	got7fsn_ti	upregulation of protein polymerization|stimulation of protein polymerization|up regulation of protein polymerization|up-regulation of protein polymerization|activation of protein polymerization													biological_process											owl:Class	
GO:0048401	biolink:NamedThing	negative regulation of intermediate mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.	got7fsn_ti	down-regulation of intermediate mesodermal cell fate specification|inhibition of intermediate mesodermal cell fate specification|downregulation of intermediate mesodermal cell fate specification|down regulation of intermediate mesodermal cell fate specification													biological_process											owl:Class	
GO:0060124	biolink:NamedThing	positive regulation of growth hormone secretion	Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0052474	biolink:NamedThing	obsolete negative regulation by organism of symbiont T-cell mediated immune response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of symbiont T-cell mediated immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:2000339	biolink:NamedThing	negative regulation of chemokine (C-X-C motif) ligand 1 production	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.	got7fsn_ti	negative regulation of keratinocyte derived chemokine production|negative regulation of KC production|negative regulation of CXCL1 production|negative regulation of SCYB1 production						mah	2011-02-01T10:46:31Z						biological_process											owl:Class	
GO:2001126	biolink:NamedThing	positive regulation of translational frameshifting	Any process that activates or increases the frequency, rate or extent of translational frameshifting.	got7fsn_ti							dph	2011-10-12T05:52:30Z						biological_process											owl:Class	
GO:0045641	biolink:NamedThing	negative regulation of basophil differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation.	got7fsn_ti	down regulation of basophil differentiation|down-regulation of basophil differentiation|downregulation of basophil differentiation|inhibition of basophil differentiation													biological_process											owl:Class	
GO:0019413	biolink:NamedThing	acetate biosynthetic process	The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.	got7fsn_ti	acetate synthesis|acetate biosynthesis|acetate anabolism|acetate formation													biological_process											owl:Class	
GO:0005574	biolink:NamedThing	obsolete DNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DNA				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0140202	biolink:NamedThing	polyamine import across plasma membrane	The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-02-20T10:24:54Z						biological_process											owl:Class	
GO:1905612	biolink:NamedThing	positive regulation of mRNA cap binding	Any process that activates or increases the frequency, rate or extent of mRNA cap binding.	got7fsn_ti	activation of mRNA cap binding|up-regulation of mRNA cap binding|up regulation of mRNA cap binding|upregulation of mRNA cap binding						bc	2016-10-28T11:27:43Z						biological_process											owl:Class	
GO:2001223	biolink:NamedThing	negative regulation of neuron migration	Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.	got7fsn_ti	negative regulation of neuronal migration|negative regulation of neuron chemotaxis|negative regulation of neuron guidance						kmv	2011-11-17T10:01:45Z						biological_process											owl:Class	
GO:1905104	biolink:NamedThing	obsolete response to ouabain	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-04-04T19:08:07Z		True				biological_process											owl:Class	
GO:1900072	biolink:NamedThing	positive regulation of sulfite transport	Any process that activates or increases the frequency, rate or extent of sulfite transport.	got7fsn_ti	activation of sulfite transport|activation of sulphite transport|up regulation of sulfite transport|positive regulation of sulphite transport|up regulation of sulphite transport|up-regulation of sulphite transport|upregulation of sulfite transport|up-regulation of sulfite transport|upregulation of sulphite transport						dph	2012-01-26T08:41:16Z						biological_process											owl:Class	
GO:1901710	biolink:NamedThing	regulation of homoserine biosynthetic process	Any process that modulates the frequency, rate or extent of homoserine biosynthetic process.	got7fsn_ti	regulation of homoserine synthesis|regulation of homoserine biosynthesis|regulation of homoserine anabolism|regulation of homoserine formation						mcc	2012-12-19T16:01:56Z						biological_process											owl:Class	
GO:0010185	biolink:NamedThing	regulation of cellular defense response	Any process that modulates the frequency, rate or extent of cellular defense response.	got7fsn_ti	regulation of cellular defence response													biological_process											owl:Class	
GO:1901811	biolink:NamedThing	beta-carotene catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-carotene.	got7fsn_ti	beta-carotene catabolism|beta-carotene degradation|beta-carotene breakdown						yaf	2013-01-22T10:30:28Z						biological_process											owl:Class	
GO:0062126	biolink:NamedThing	fatty acid primary amide metabolic process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides.	got7fsn_ti	primary fatty amide metabolic process						dph	2019-05-30T18:23:02Z						biological_process											owl:Class	
GO:1903961	biolink:NamedThing	positive regulation of anion transmembrane transport	Any process that activates or increases the frequency, rate or extent of anion transmembrane transport.	got7fsn_ti	activation of anion transmembrane transport|upregulation of anion transmembrane transport|up regulation of anion transmembrane transport|up-regulation of anion transmembrane transport						pr	2015-02-25T13:52:44Z						biological_process											owl:Class	
GO:1904536	biolink:NamedThing	regulation of mitotic telomere tethering at nuclear periphery	Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.	got7fsn_ti							al	2015-08-04T14:24:26Z						biological_process											owl:Class	
GO:0008508	biolink:NamedThing	bile acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in).	got7fsn_ti	sodium/bile acid symporter activity											Reactome:R-HSA-433089|Reactome:R-HSA-194121|Reactome:R-HSA-194187		molecular_function											owl:Class	
GO:0005079	biolink:NamedThing	obsolete protein kinase A anchoring activity	OBSOLETE. Binds to protein kinase A and anchors it to a particular subcellular location.	got7fsn_ti	AKAP activity|protein kinase A anchoring activity|A-kinase anchor protein activity				This term was made obsolete because it represents a combination of process and function information.	GO:0051018|GO:0008104				True				molecular_function											owl:Class	
GO:0075249	biolink:NamedThing	positive regulation of aeciospore formation	Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.	got7fsn_ti														biological_process											owl:Class	
GO:1903847	biolink:NamedThing	regulation of aorta morphogenesis	Any process that modulates the frequency, rate or extent of aorta morphogenesis.	got7fsn_ti							rph	2015-01-23T14:00:51Z						biological_process											owl:Class	
GO:0005082	biolink:NamedThing	obsolete receptor signaling protein tyrosine phosphatase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	receptor signaling protein tyrosine phosphatase signaling protein activity|receptor signalling protein tyrosine phosphatase signalling protein activity				This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556				True				molecular_function											owl:Class	
GO:1902353	biolink:NamedThing	obsolete positive regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter by pheromones that results in positive regulation of induction of conjugation with cellular fusion.	got7fsn_ti	upregulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones|up regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones|up-regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones				This term was obsoleted because it represents a GO-CAM model.		bf	2013-08-14T09:45:21Z		True				biological_process											owl:Class	
CHEBI:15415	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:166829	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090188	biolink:NamedThing	negative regulation of pancreatic juice secretion	Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.	got7fsn_ti							tb	2009-12-18T11:03:24Z						biological_process											owl:Class	
GO:1903193	biolink:NamedThing	sesquarterpene biosynthetic process	The chemical reactions and pathways resulting in the formation of sesquarterpene.	got7fsn_ti	sesquarterpene anabolism|sesquarterpene biosynthesis|sesquarterpene synthesis|sesquarterpene formation						tt	2014-07-16T17:04:53Z						biological_process											owl:Class	
GO:0015966	biolink:NamedThing	diadenosine tetraphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.	got7fsn_ti	diadenosine tetraphosphate anabolism|diadenosine tetraphosphate synthesis|diadenosine tetraphosphate formation|diadenosine tetraphosphate biosynthesis													biological_process											owl:Class	
GO:1905490	biolink:NamedThing	negative regulation of sensory neuron axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance.	got7fsn_ti	down regulation of sensory neuron axon guidance|down-regulation of sensory neuron axon guidance|downregulation of sensory neuron axon guidance|inhibition of sensory neuron axon guidance						hbye	2016-09-23T13:19:04Z						biological_process											owl:Class	
GO:0052648	biolink:NamedThing	ribitol phosphate metabolic process	The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.	got7fsn_ti	ribitol phosphate metabolism						ai	2010-09-22T04:28:37Z						biological_process											owl:Class	
GO:0032823	biolink:NamedThing	regulation of natural killer cell differentiation	Any process that modulates the frequency, rate or extent of natural killer cell differentiation.	got7fsn_ti	regulation of natural killer cell development|regulation of NK cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1903268	biolink:NamedThing	positive regulation of ornithine catabolic process	Any process that activates or increases the frequency, rate or extent of ornithine catabolic process.	got7fsn_ti	activation of ornithine breakdown|upregulation of ornithine catabolism|up-regulation of ornithine breakdown|up-regulation of ornithine degradation|positive regulation of ornithine catabolism|upregulation of ornithine catabolic process|activation of ornithine catabolic process|up-regulation of ornithine catabolism|upregulation of ornithine degradation|positive regulation of ornithine degradation|up regulation of ornithine degradation|activation of ornithine degradation|up regulation of ornithine catabolic process|up regulation of ornithine breakdown|positive regulation of ornithine breakdown|activation of ornithine catabolism|up-regulation of ornithine catabolic process|up regulation of ornithine catabolism|upregulation of ornithine breakdown						bhm	2014-08-08T08:29:50Z						biological_process											owl:Class	
GO:0070508	biolink:NamedThing	cholesterol import	The directed movement of cholesterol into a cell or organelle.	got7fsn_ti	cholesterol uptake													biological_process											owl:Class	
GO:0009622	biolink:NamedThing	obsolete resistance to pathogenic fungi	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	resistance to pathogenic fungi			GO:0009620	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0009468	biolink:NamedThing	obsolete diheme class I cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	diheme class I cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0061310	biolink:NamedThing	canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt-activated signaling pathway involved in cardiac neural crest cell differentiation involved in heart development						dph	2010-09-23T09:12:36Z						biological_process											owl:Class	
GO:1903984	biolink:NamedThing	positive regulation of TRAIL-activated apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.	got7fsn_ti	activation of TRAIL-activated apoptotic signaling pathway|up-regulation of TRAIL-activated extrinsic apoptotic signaling pathway|positive regulation of TRAIL-induced apoptotic signaling pathway|activation of TRAIL-induced apoptotic signaling pathway|activation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up-regulation of TRAIL-induced apoptotic signaling pathway|positive regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up regulation of TRAIL-activated extrinsic apoptotic signaling pathway|up-regulation of TRAIL-activated apoptotic signaling pathway|up-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|upregulation of TRAIL-induced apoptotic signaling pathway|positive regulation of TRAIL-activated extrinsic apoptotic signaling pathway|upregulation of TRAIL-activated apoptotic signaling pathway|upregulation of TRAIL-activated extrinsic apoptotic signaling pathway|activation of TRAIL-activated extrinsic apoptotic signaling pathway|up regulation of TRAIL-induced apoptotic signaling pathway|up regulation of TRAIL-activated apoptotic signaling pathway|upregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway						bf	2015-03-03T15:04:21Z						biological_process											owl:Class	
GO:0055126	biolink:NamedThing	obsolete Nup82 complex	OBSOLETE. A protein complex that forms part of the nuclear pore complex. It forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p, and is required for proper localization of Nup116p. In Saccharomyces cerevisiae this complex contains Nup82p, Nsp1p, Nup159p, Nup116p, and Gle2p.	got7fsn_ti	Nup82 complex					GO:0044612	jid	2009-10-12T08:35:34Z		True				cellular_component											owl:Class	
GO:0034193	biolink:NamedThing	L-galactonate metabolic process	The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid.	got7fsn_ti	L-galactonate metabolism													biological_process											owl:Class	
GO:0008943	biolink:NamedThing	obsolete glyceraldehyde-3-phosphate dehydrogenase activity	OBSOLETE. Catalysis of the reactions: glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl-phosphate + NAD(P)H + H+, and glyceraldehyde 3-phosphate + H2O + NAD(P)+ = 3-phospho-D-glycerate + NAD(P)H + H+.	got7fsn_ti	glyceraldehyde-3-phosphate dehydrogenase activity				This term was made obsolete because it is a grouping term based on similar names.	GO:0004365|GO:0047100|GO:0043878|GO:0008886				True				molecular_function											owl:Class	
GO:1901003	biolink:NamedThing	negative regulation of fermentation	Any process that stops, prevents or reduces the frequency, rate or extent of fermentation.	got7fsn_ti	downregulation of fermentation|down-regulation of fermentation|down regulation of fermentation|inhibition of fermentation						al	2012-06-15T08:21:31Z						biological_process											owl:Class	
GO:0070372	biolink:NamedThing	regulation of ERK1 and ERK2 cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.	got7fsn_ti	regulation of ERK cascade|regulation of ERK1 and ERK2 signaling pathway|regulation of MAPK1 cascade|regulation of ERK2 cascade|regulation of ERK1 and ERK2 signalling pathway|regulation of ERK1 cascade|regulation of MAPK3 cascade|regulation of ERK1/2 cascade													biological_process											owl:Class	
GO:0046763	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:64436	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901665	biolink:NamedThing	negative regulation of NAD+ ADP-ribosyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.	got7fsn_ti	negative regulation of NAD ADP-ribosyltransferase activity|inhibition of NAD ADP-ribosyltransferase activity|downregulation of ADP-ribosyltransferase (polymerizing) activity|downregulation of NAD ADP-ribosyltransferase activity|negative regulation of poly(ADP-ribose) synthase activity|down-regulation of NAD ADP-ribosyltransferase activity|inhibition of poly(ADP-ribose) synthetase activity|down regulation of poly(adenosine diphosphate ribose) polymerase activity|down regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|down regulation of NAD ADP-ribosyltransferase activity|negative regulation of poly(adenosine diphosphate ribose) polymerase activity|downregulation of poly(ADP-ribose) synthase activity|inhibition of NAD+ ADP-ribosyltransferase activity|negative regulation of poly(ADP-ribose) synthetase activity|downregulation of poly(adenosine diphosphate ribose) polymerase activity|down-regulation of poly(ADP-ribose)polymerase activity|downregulation of poly(ADP-ribose)polymerase activity|down regulation of poly(ADP-ribose) synthetase activity|downregulation of poly(ADP-ribose) synthetase activity|negative regulation of ADP-ribosyltransferase (polymerizing) activity|negative regulation of poly(ADP-ribose)polymerase activity|downregulation of NAD+ ADP-ribosyltransferase activity|down regulation of poly(ADP-ribose) synthase activity|inhibition of poly(ADP-ribose) synthase activity|down-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|down-regulation of ADP-ribosyltransferase (polymerizing) activity|inhibition of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|down-regulation of poly(adenosine diphosphate ribose) polymerase activity|down-regulation of poly(ADP-ribose) synthase activity|down regulation of NAD+ ADP-ribosyltransferase activity|inhibition of poly(adenosine diphosphate ribose) polymerase activity|down-regulation of NAD+ ADP-ribosyltransferase activity|down-regulation of poly(ADP-ribose) synthetase activity|down regulation of ADP-ribosyltransferase (polymerizing) activity|down regulation of poly(ADP-ribose)polymerase activity|downregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|inhibition of ADP-ribosyltransferase (polymerizing) activity|negative regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|inhibition of poly(ADP-ribose)polymerase activity						vk	2012-11-20T18:50:15Z						biological_process											owl:Class	
GO:0034767	biolink:NamedThing	positive regulation of ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.	got7fsn_ti	positive regulation of ion membrane transport|activation of transmembrane ion transport|up-regulation of transmembrane ion transport|positive regulation of transmembrane ion transport|upregulation of transmembrane ion transport|up regulation of transmembrane ion transport|stimulation of transmembrane ion transport													biological_process											owl:Class	
GO:0016804	biolink:NamedThing	obsolete prolyl aminopeptidase activity	OBSOLETE. Catalysis of the release of a N-terminal proline from a peptide.	got7fsn_ti	prolyl aminopeptidase activity|proline aminopeptidase|proline iminopeptidase activity|Pro-X aminopeptidase activity|cytosol aminopeptidase V			GO:0004177	This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.					True				molecular_function											owl:Class	
GO:0043343	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032058	biolink:NamedThing	positive regulation of translational initiation in response to stress	Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.	got7fsn_ti	up regulation of translation initiation in response to stress|stimulation of translation initiation in response to stress|upregulation of translation initiation in response to stress|activation of translation initiation in response to stress|up-regulation of translation initiation in response to stress													biological_process											owl:Class	
GO:0052646	biolink:NamedThing	alditol phosphate metabolic process	The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.	got7fsn_ti	alditol phosphate metabolism						ai	2010-09-22T04:24:21Z						biological_process											owl:Class	
GO:0015005	biolink:NamedThing	obsolete azurin	OBSOLETE. Brilliant blue copper-containing protein of low molecular weight found in some bacteria; thought to transfer electrons to cytochrome oxidase. This definition includes pseudoazurin.	got7fsn_ti	azurin				This term was made obsolete because it does not represent a molecular function.	GO:0009055				True				molecular_function											owl:Class	
GO:0008075	biolink:NamedThing	obsolete receptor guanylate cyclase activity	OBSOLETE. Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.	got7fsn_ti	receptor guanylate cyclase activity				This term was made obsolete because it represents a class of gene products.	GO:0038023|GO:0004383				True				molecular_function											owl:Class	
GO:0030530	biolink:NamedThing	obsolete heterogeneous nuclear ribonucleoprotein complex	OBSOLETE. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA.	got7fsn_ti	heterogeneous nuclear ribonucleoprotein complex|hnRNP|heterogeneous nuclear ribonucleoprotein				This term was made because heterogeneous nuclear ribonucleoprotein is an experimental construct and does not correspond cleanly to a functional cellular entity.	GO:0005681|GO:1990904				True		Wikipedia:Heterogeneous_ribonucleoprotein_particle		cellular_component											owl:Class	
GO:1900394	biolink:NamedThing	regulation of kojic acid biosynthetic process	Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process.	got7fsn_ti	regulation of kojic acid anabolism|regulation of C6H6O4 anabolism|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|regulation of C6H6O4 formation|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|regulation of kojic acid formation|regulation of C6H6O4 synthesis|regulation of kojic acid synthesis|regulation of C6H6O4 biosynthetic process|regulation of kojic acid biosynthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|regulation of C6H6O4 biosynthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis						di	2012-04-18T04:19:53Z						biological_process											owl:Class	
GO:1905119	biolink:NamedThing	response to haloperidol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2016-04-08T12:36:39Z						biological_process											owl:Class	
GO:2000637	biolink:NamedThing	positive regulation of gene silencing by miRNA	Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA.	got7fsn_ti	positive regulation of miRNA-mediated gene silencing|positive regulation of microRNA-mediated gene silencing|positive regulation of gene silencing by microRNA						dph	2011-04-18T03:51:24Z						biological_process											owl:Class	
GO:2000218	biolink:NamedThing	negative regulation of invasive growth in response to glucose limitation	Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation.	got7fsn_ti	negative regulation of colony morphology						mah	2010-11-03T04:36:00Z						biological_process											owl:Class	
GO:1904137	biolink:NamedThing	negative regulation of convergent extension involved in notochord morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis.	got7fsn_ti	down regulation of convergent extension involved in notochord morphogenesis|inhibition of convergent extension involved in notochord morphogenesis|down-regulation of convergent extension involved in notochord morphogenesis|downregulation of convergent extension involved in notochord morphogenesis						dph	2015-04-10T21:21:36Z						biological_process											owl:Class	
GO:0033358	biolink:NamedThing	UDP-L-arabinose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-L-arabinose formation|UDP-L-arabinose synthesis|UDP-L-arabinose anabolism|UDP-L-arabinose biosynthesis											MetaCyc:PWY-82|MetaCyc:PWY-63		biological_process											owl:Class	
GO:0010978	biolink:NamedThing	obsolete gene silencing involved in chronological cell aging	OBSOLETE. Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18632			This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398	tb	2009-06-01T11:39:42Z		True				biological_process											owl:Class	
GO:0051891	biolink:NamedThing	positive regulation of cardioblast differentiation	Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	up regulation of cardioblast differentiation|stimulation of cardioblast differentiation|activation of cardioblast differentiation|up-regulation of cardioblast differentiation|upregulation of cardioblast differentiation													biological_process											owl:Class	
GO:1903547	biolink:NamedThing	regulation of growth hormone activity	Any process that modulates the frequency, rate or extent of growth hormone activity.	got7fsn_ti	regulation of GH activity|regulation of placental growth hormone activity|regulation of pituitary growth hormone activity						mr	2014-10-20T15:18:36Z						biological_process											owl:Class	
GO:0071304	biolink:NamedThing	cellular response to vitamin B6	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	got7fsn_ti							mah	2009-12-10T04:35:23Z						biological_process											owl:Class	
GO:0047063	biolink:NamedThing	obsolete L-ascorbate-cytochrome-b5 reductase activity	OBSOLETE. Catalysis of the reaction: ferricytochrome B5 + ascorbate = ferrocytochrome B5 + monodehydroascorbate.	got7fsn_ti	ascorbate-cytochrome b5 reductase activity|L-ascorbate:ferricytochrome-b5 oxidoreductase activity				This term was obsoleted because the EC and RHEA it represented was obsoleted.					True		EC:1.10.2.1|RHEA:18677|MetaCyc:1.10.2.1-RXN		molecular_function											owl:Class	
GO:0090186	biolink:NamedThing	regulation of pancreatic juice secretion	Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.	got7fsn_ti							tb	2009-12-18T11:03:24Z						biological_process											owl:Class	
GO:1904891	biolink:NamedThing	positive regulation of excitatory synapse assembly	Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly.	got7fsn_ti	up-regulation of excitatory synapse assembly|up regulation of excitatory synapse assembly|positive regulation of excitatory synapse formation|up-regulation of excitatory synapse formation|activation of excitatory synapse assembly|upregulation of excitatory synapse assembly|up regulation of excitatory synapse formation|activation of excitatory synapse formation|upregulation of excitatory synapse formation						bf	2016-01-07T14:36:07Z						biological_process											owl:Class	
GO:0051339	biolink:NamedThing	regulation of lyase activity	Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.	got7fsn_ti	lyase regulator													biological_process											owl:Class	
GO:0000903	biolink:NamedThing	obsolete regulation of cell shape during vegetative growth phase	OBSOLETE. Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods.	got7fsn_ti	cell morphogenesis during vegetative growth phase|cellular morphogenesis during vegetative growth|regulation of cell morphogenesis during vegetative growth phase				The reason for obsoletion is that biological phases should be captured as extensions.					True	GO:0090061			biological_process											owl:Class	
GO:1903141	biolink:NamedThing	negative regulation of establishment of endothelial barrier	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier.	got7fsn_ti	inhibition of establishment of endothelial barrier|down regulation of establishment of endothelial barrier|down-regulation of establishment of endothelial barrier|downregulation of establishment of endothelial barrier						als	2014-07-01T12:12:40Z						biological_process											owl:Class	
GO:0052119	biolink:NamedThing	obsolete negative energy taxis in host environment	OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative energy taxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0061094	biolink:NamedThing	regulation of turning behavior involved in mating	Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.	got7fsn_ti							dph	2010-04-26T02:12:24Z						biological_process											owl:Class	
GO:0034615	biolink:NamedThing	GCH1 complex	A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive.	got7fsn_ti	GTP cyclohydrolase I complex													cellular_component											owl:Class	
GO:0019374	biolink:NamedThing	galactolipid metabolic process	The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.	got7fsn_ti	galactolipid metabolism													biological_process											owl:Class	
GO:1901915	biolink:NamedThing	positive regulation of capsule organization	Any process that activates or increases the frequency, rate or extent of capsule organization.	got7fsn_ti	activation of capsule organization and biogenesis|upregulation of capsule organization and biogenesis|positive regulation of capsule organisation|upregulation of capsule organization|up regulation of capsule organization and biogenesis|up regulation of capsule organization|up regulation of capsule organisation|activation of capsule organisation|upregulation of capsule organisation|up-regulation of capsule organization|activation of capsule organization|up-regulation of capsule organisation|up-regulation of capsule organization and biogenesis|positive regulation of capsule organization and biogenesis						di	2013-02-14T06:19:16Z						biological_process											owl:Class	
GO:0004172	biolink:NamedThing	obsolete ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity				This term was made obsolete because it represents two molecular functions.	GO:0050488				True				molecular_function											owl:Class	
GO:0070105	biolink:NamedThing	positive regulation of interleukin-6-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.	got7fsn_ti	positive regulation of interleukin-6-mediated signalling pathway|positive regulation of IL-6-mediated signaling pathway													biological_process											owl:Class	
GO:0033690	biolink:NamedThing	positive regulation of osteoblast proliferation	Any process that activates or increases the rate or extent of osteoblast proliferation.	got7fsn_ti	up regulation of osteoblast proliferation|up-regulation of osteoblast proliferation|stimulation of osteoblast proliferation|activation of osteoblast proliferation|upregulation of osteoblast proliferation													biological_process											owl:Class	
GO:0071876	biolink:NamedThing	obsolete initiation of adrenergic receptor signal transduction	OBSOLETE. A process of signal initiation in which epinephrine or norepinephrine causes activation of an adrenergic receptor.	got7fsn_ti	initiation of adrenergic receptor signal transduction				This term was made obsolete because the meaning of the term is ambiguous.	GO:0071874|GO:0071872|GO:0071875|GO:0005179|GO:0004935	mah	2010-09-13T04:05:38Z		True				biological_process											owl:Class	
GO:0046881	biolink:NamedThing	positive regulation of follicle-stimulating hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.	got7fsn_ti	positive regulation of follicle stimulating hormone secretion|up-regulation of follicle-stimulating hormone secretion|stimulation of follicle-stimulating hormone secretion|upregulation of follicle-stimulating hormone secretion|activation of follicle-stimulating hormone secretion|up regulation of follicle-stimulating hormone secretion													biological_process											owl:Class	
GO:0033135	biolink:NamedThing	regulation of peptidyl-serine phosphorylation	Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.	got7fsn_ti														biological_process											owl:Class	
GO:1901931	biolink:NamedThing	alpha-copaene biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-copaene.	got7fsn_ti	alpha-copaene anabolism|alpha-copaene synthesis|alpha-copaene formation|alpha-copaene biosynthesis						ms	2013-02-18T14:54:48Z						biological_process											owl:Class	
GO:1905570	biolink:NamedThing	positive regulation of ferrichrome biosynthetic process	Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process.	got7fsn_ti	upregulation of ferrichrome anabolism|up regulation of ferrichrome formation|positive regulation of ferrichrome anabolism|positive regulation of ferrichrome biosynthesis|up regulation of ferrichrome biosynthetic process|up-regulation of ferrichrome biosynthesis|positive regulation of ferrichrome formation|activation of ferrichrome biosynthetic process|up regulation of ferrichrome synthesis|upregulation of ferrichrome biosynthetic process, peptide formation|up regulation of ferrichrome biosynthetic process, peptide modification|up-regulation of ferrichrome biosynthetic process, peptide formation|positive regulation of ferrichrome biosynthetic process, peptide modification|upregulation of ferrichrome formation|up-regulation of ferrichrome biosynthetic process|up-regulation of ferrichrome anabolism|up-regulation of ferrichrome synthesis|up-regulation of ferrichrome biosynthetic process, peptide modification|upregulation of ferrichrome synthesis|positive regulation of ferrichrome biosynthetic process, peptide formation|activation of ferrichrome synthesis|up-regulation of ferrichrome formation|positive regulation of ferrichrome synthesis|activation of ferrichrome biosynthesis|upregulation of ferrichrome biosynthesis|activation of ferrichrome biosynthetic process, peptide modification|activation of ferrichrome formation|upregulation of ferrichrome biosynthetic process, peptide modification|up regulation of ferrichrome biosynthesis|upregulation of ferrichrome biosynthetic process|up regulation of ferrichrome biosynthetic process, peptide formation|activation of ferrichrome biosynthetic process, peptide formation|up regulation of ferrichrome anabolism|activation of ferrichrome anabolism						pr	2016-10-18T14:49:16Z						biological_process											owl:Class	
CHEBI:58069	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051511	biolink:NamedThing	negative regulation of unidimensional cell growth	Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.	got7fsn_ti	downregulation of unidimensional cell growth|down-regulation of unidimensional cell growth|down regulation of unidimensional cell growth|inhibition of unidimensional cell growth|negative regulation of cell elongation													biological_process											owl:Class	
GO:1903965	biolink:NamedThing	monounsaturated fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid.	got7fsn_ti	monounsaturated fatty acid catabolism|monounsaturated fatty acid degradation|monounsaturated fatty acid breakdown						pr	2015-02-25T20:35:58Z						biological_process											owl:Class	
GO:2000214	biolink:NamedThing	regulation of proline metabolic process	Any process that modulates the frequency, rate or extent of proline metabolic process.	got7fsn_ti	regulation of proline metabolism						mah	2010-11-03T02:45:20Z						biological_process											owl:Class	
GO:1900505	biolink:NamedThing	positive regulation of cellulosome assembly	Any process that activates or increases the frequency, rate or extent of cellulosome assembly.	got7fsn_ti	up-regulation of cellulosome assembly|up regulation of cellulosome assembly|upregulation of cellulosome assembly|activation of cellulosome assembly						tt	2012-05-02T03:58:35Z						biological_process											owl:Class	
GO:0090195	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030800	biolink:NamedThing	obsolete negative regulation of cyclic nucleotide metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.	got7fsn_ti	inhibition of cyclic nucleotide metabolic process|down regulation of cyclic nucleotide metabolic process|negative regulation of cyclic nucleotide metabolism|downregulation of cyclic nucleotide metabolic process|down-regulation of cyclic nucleotide metabolic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:1902482	biolink:NamedThing	regulatory T cell apoptotic process	Any apoptotic process in a regulatory T cell.	got7fsn_ti	regulatory T-lymphocyte apoptosis|regulatory T-cell apoptotic process|regulatory T-cell apoptosis|regulatory T lymphocyte apoptosis|regulatory T-lymphocyte apoptotic process|regulatory T lymphocyte apoptotic process|regulatory T cell apoptosis						nhn	2013-11-04T17:18:09Z						biological_process											owl:Class	
GO:0033303	biolink:NamedThing	quercetin O-glucoside biosynthetic process	The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.	got7fsn_ti	quercetin O-glucoside anabolism|quercetin O-glucoside formation|quercetin O-glucoside synthesit|quercetin O-glucoside biosynthesis											MetaCyc:PWY-5321		biological_process											owl:Class	
GO:0062002	biolink:NamedThing	regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.	got7fsn_ti							dph	2018-02-26T13:16:39Z						biological_process											owl:Class	
GO:0003719	biolink:NamedThing	obsolete transcription factor binding, cytoplasmic sequestering	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transcription factor binding, cytoplasmic sequestering			GO:0042994	This term was made obsolete because sequestering is a process rather than a function.					True				molecular_function											owl:Class	
GO:1900370	biolink:NamedThing	positive regulation of RNA interference	Any process that activates or increases the frequency, rate or extent of RNA interference.	got7fsn_ti	activation of posttranscriptional gene silencing by siRNA|positive regulation of posttranscriptional gene silencing by siRNA|activation of RNAi|up regulation of posttranscriptional gene silencing by siRNA|upregulation of RNA interference|upregulation of posttranscriptional gene silencing by siRNA|activation of RNA interference|up-regulation of RNA interference|upregulation of RNAi|positive regulation of RNAi|up regulation of RNA interference|up-regulation of RNAi|up-regulation of posttranscriptional gene silencing by siRNA|up regulation of RNAi						kmv	2012-04-13T08:29:00Z						biological_process											owl:Class	
GO:1990750	biolink:NamedThing	obsolete axon shaft	OBSOLETE. Main portion of an axon, excluding terminal, spines, or dendrites.	got7fsn_ti	axonal shaft				This term was made obsolete because it was added in error.	GO:0044304	sl	2015-05-21T17:46:18Z		True				cellular_component											owl:Class	
GO:0072743	biolink:NamedThing	cellular response to erythromycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.	got7fsn_ti							mah	2012-08-31T12:24:52Z						biological_process											owl:Class	
GO:1900671	biolink:NamedThing	negative regulation of F-9775A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process.	got7fsn_ti	downregulation of F-9775A synthesis|negative regulation of F-9775A anabolism|down regulation of F-9775A biosynthesis|down regulation of F-9775A formation|inhibition of F-9775A synthesis|down-regulation of F-9775A anabolism|inhibition of F-9775A anabolism|down regulation of F-9775A anabolism|downregulation of F-9775A biosynthesis|negative regulation of F-9775A formation|down regulation of F-9775A synthesis|negative regulation of F-9775A biosynthesis|negative regulation of F-9775A synthesis|inhibition of F-9775A biosynthetic process|inhibition of F-9775A formation|downregulation of F-9775A formation|downregulation of F-9775A biosynthetic process|down-regulation of F-9775A synthesis|down-regulation of F-9775A formation|down-regulation of F-9775A biosynthesis|inhibition of F-9775A biosynthesis|down-regulation of F-9775A biosynthetic process|down regulation of F-9775A biosynthetic process|downregulation of F-9775A anabolism						di	2012-05-22T04:24:30Z						biological_process											owl:Class	
GO:1904905	biolink:NamedThing	negative regulation of endothelial cell-matrix adhesion via fibronectin	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.	got7fsn_ti	inhibition of endothelial cell-matrix adhesion via fibronectin|down-regulation of endothelial cell-matrix adhesion via fibronectin|downregulation of endothelial cell-matrix adhesion via fibronectin|down regulation of endothelial cell-matrix adhesion via fibronectin						bc	2016-01-19T10:23:09Z						biological_process											owl:Class	
GO:1903857	biolink:NamedThing	negative regulation of cytokinin dehydrogenase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity.	got7fsn_ti	inhibition of N6-dimethylallyladenine:acceptor oxidoreductase activity|downregulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|inhibition of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down-regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of cytokinin dehydrogenase activity|negative regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|negative regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|negative regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of cytokinin oxidase activity|downregulation of cytokinin dehydrogenase activity|down-regulation of cytokinin oxidase activity|inhibition of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of cytokinin oxidase activity|negative regulation of cytokinin oxidase activity|down-regulation of cytokinin dehydrogenase activity|down regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of cytokinin oxidase activity|down regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|downregulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of cytokinin dehydrogenase activity						tb	2015-01-30T00:34:01Z						biological_process											owl:Class	
GO:1905899	biolink:NamedThing	regulation of smooth muscle tissue development	Any process that modulates the frequency, rate or extent of smooth muscle tissue development.	got7fsn_ti							bhm	2017-02-01T14:31:16Z						biological_process											owl:Class	
GO:0051181	biolink:NamedThing	obsolete cofactor transport	OBSOLETE. The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein.	got7fsn_ti	vitamin or cofactor transport				1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a cofactor.					True				biological_process											owl:Class	
GO:1990976	biolink:NamedThing	protein transport along microtubule to mitotic spindle pole body	The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins.	got7fsn_ti							vw	2016-06-30T13:09:08Z						biological_process											owl:Class	
GO:0003819	biolink:NamedThing	obsolete major histocompatibility complex antigen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	major histocompatibility complex antigen|MHC protein				This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True				molecular_function											owl:Class	
GO:0009465	biolink:NamedThing	obsolete soluble cytochrome b562	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	soluble cytochrome b562			GO:0004129	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:2000231	biolink:NamedThing	positive regulation of pancreatic stellate cell proliferation	Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation.	got7fsn_ti							mah	2010-11-09T03:45:23Z						biological_process											owl:Class	
GO:0017043	biolink:NamedThing	obsolete adrenocorticotropin	OBSOLETE. A polypeptide hormone which stimulates the adrenal cortex to synthesize and secrete glucocorticoid hormones.	got7fsn_ti	adrenocorticotropin|corticotropin				This term was made obsolete because it represents a gene product.	GO:0046887|GO:0046886|GO:0005102				True				molecular_function											owl:Class	
UBERON:0002353	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044240	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016734	biolink:NamedThing	obsolete molybdenum-iron nitrogenase activity	OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.	got7fsn_ti	molybdenum-iron nitrogenase activity				This term was made obsolete because it represents a cellular component.	GO:0016163|GO:0016612				True				molecular_function											owl:Class	
GO:2000565	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta T cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.	got7fsn_ti							ebc	2011-04-03T09:03:19Z						biological_process											owl:Class	
GO:0052570	biolink:NamedThing	obsolete response to defense-related symbiont reactive oxygen species production	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	response to defense-related symbiont reactive oxygen species production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0035388	biolink:NamedThing	positive regulation of Roundabout signaling pathway	Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway.	got7fsn_ti	positive regulation of Roundabout signalling pathway						bf	2010-03-18T02:41:16Z						biological_process											owl:Class	
GO:1901942	biolink:NamedThing	(+)-epi-alpha-bisabolol catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.	got7fsn_ti	(+)-epi-alpha-bisabolol degradation|(+)-epi-alpha-bisabolol breakdown|(+)-epi-alpha-bisabolol catabolism						ms	2013-02-18T14:55:41Z						biological_process											owl:Class	
GO:0044338	biolink:NamedThing	canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in mesenchymal stem cell differentiation|canonical Wnt-activated signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation						jl	2010-08-20T03:43:36Z						biological_process											owl:Class	
GO:0033222	biolink:NamedThing	xylose binding	Binding to the D- or L-enantiomer of xylose.	got7fsn_ti														molecular_function											owl:Class	
GO:1903864	biolink:NamedThing	P granule disassembly	The disaggregation of a P granule into its constituent components.	got7fsn_ti	germline granule disassembly|polar granule disassembly						kmv	2015-02-04T15:27:12Z						biological_process											owl:Class	
GO:0045874	biolink:NamedThing	positive regulation of sevenless signaling pathway	Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway.	got7fsn_ti	positive regulation of sevenless signalling pathway|positive regulation of sev signaling pathway|up-regulation of sevenless signaling pathway|up regulation of sevenless signaling pathway|stimulation of sevenless signaling pathway|activation of sevenless signaling pathway|upregulation of sevenless signaling pathway													biological_process											owl:Class	
GO:1901909	biolink:NamedThing	diadenosine hexaphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate.	got7fsn_ti	diadenosine hexaphosphate catabolism|diadenosyl hexaphosphate catabolic process|diadenosyl hexaphosphate breakdown|diadenosyl hexaphosphate degradation|diadenosyl hexaphosphate catabolism						al	2013-02-13T13:50:44Z						biological_process											owl:Class	
GO:0009807	biolink:NamedThing	lignan biosynthetic process	The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.	got7fsn_ti	lignan synthesis|lignan formation|lignan biosynthesis|lignan anabolism													biological_process											owl:Class	
GO:0072381	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	got7fsn_ti	positive regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|positive regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|positive regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|positive regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation						mah	2010-11-24T03:10:15Z						biological_process											owl:Class	
GO:0039710	biolink:NamedThing	cytoplasmic icosahedral capsid assembly	The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome.	got7fsn_ti							bf	2013-11-28T15:20:50Z						biological_process											owl:Class	
GO:2000282	biolink:NamedThing	regulation of cellular amino acid biosynthetic process	Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.	got7fsn_ti	regulation of cellular amino acid formation|regulation of cellular amino acid anabolism|regulation of cellular amino acid synthesis|regulation of amino acid biosynthetic process|regulation of cellular amino acid biosynthesis						vw	2010-12-10T11:54:19Z						biological_process											owl:Class	
GO:0100002	biolink:NamedThing	negative regulation of protein kinase activity by protein phosphorylation	Any protein phosphorylation process that negatively regulates protein kinase activity.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
GO:2000972	biolink:NamedThing	positive regulation of detection of glucose	Any process that activates or increases the frequency, rate or extent of detection of glucose.	got7fsn_ti	positive regulation of glucose perception|positive regulation of glucose detection|positive regulation of glucose sensing						vk	2011-08-02T10:18:56Z						biological_process											owl:Class	
GO:0006731	biolink:NamedThing	obsolete coenzyme and prosthetic group metabolic process	OBSOLETE. The chemical reactions and pathways involving coenzymes and prosthetic groups.	got7fsn_ti	coenzyme and prosthetic group metabolic process				This term was made obsolete because it was replaced by more specific terms.	GO:0051189				True				biological_process											owl:Class	
GO:0003795	biolink:NamedThing	obsolete antimicrobial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, microbial cells.	got7fsn_ti	antimicrobial peptide activity				This term was made obsolete because it describes involvement in a process and not a function.	GO:0019730				True				molecular_function											owl:Class	
GO:0010835	biolink:NamedThing	regulation of protein ADP-ribosylation	Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.	got7fsn_ti	regulation of protein amino acid ADP-ribosylation													biological_process											owl:Class	
GO:0046866	biolink:NamedThing	tetraterpenoid transport	The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units.	got7fsn_ti														biological_process											owl:Class	
GO:1901750	biolink:NamedThing	leukotriene D4 biosynthetic process	The chemical reactions and pathways resulting in the formation of leukotriene D4.	got7fsn_ti	leukotriene D4 formation|leukotriene D4 biosynthesis|leukotriene D4 anabolism|leukotriene D4 synthesis						yaf	2013-01-14T10:56:21Z						biological_process											owl:Class	
GO:0009463	biolink:NamedThing	obsolete cytochrome b/b6	OBSOLETE. Diheme cytochrome b; cytochrome b has the hemes b(562) and b(566) and is a component of the mitochondrial respiratory chain complex III. Cytochrome b6 is a component of bc complex acting between photosystems II and I of photosynthesis.	got7fsn_ti	cytochrome b/b6			GO:0045158	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0016313	biolink:NamedThing	obsolete inositol-1,4,5-trisphosphate phosphatase	OBSOLETE. The removal of one of the phosphate groups from an inositol triphosphate to produce an inositol bisphosphate.	got7fsn_ti	inositol-1,4,5-trisphosphate phosphatase				This term was made obsolete because it is a redundant grouping term with only one child.	GO:0046030				True				molecular_function											owl:Class	
GO:1905377	biolink:NamedThing	response to D-galactose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.	got7fsn_ti	response to D-galacto-hexose|response to D-Gal						sl	2016-08-17T22:17:25Z						biological_process											owl:Class	
GO:1902769	biolink:NamedThing	regulation of choline O-acetyltransferase activity	Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity.	got7fsn_ti	regulation of acetyl-CoA:choline O-acetyltransferase activity|regulation of choline acetyltransferase activity|regulation of CHOACTase activity|regulation of choline acetylase activity						mr	2014-03-11T18:54:26Z						biological_process											owl:Class	
GO:2000472	biolink:NamedThing	negative regulation of hematopoietic stem cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration.	got7fsn_ti	negative regulation of hemopoietic stem cell migration						bf	2011-03-09T09:34:54Z						biological_process											owl:Class	
GO:0010740	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900367	biolink:NamedThing	positive regulation of defense response to insect	Any process that activates or increases the frequency, rate or extent of defense response to insect.	got7fsn_ti	upregulation of defense response to insect|activation of physiological defense response to insect|positive regulation of physiological defense response to insect|up-regulation of defense response to insect|up-regulation of physiological defense response to insect|up regulation of physiological defense response to insect|activation of defense response to insect|upregulation of physiological defense response to insect|up regulation of defense response to insect						dhl	2012-04-12T04:44:10Z						biological_process											owl:Class	
GO:0002734	biolink:NamedThing	negative regulation of myeloid dendritic cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.	got7fsn_ti	downregulation of myeloid dendritic cell cytokine production|down regulation of myeloid dendritic cell cytokine production|inhibition of myeloid dendritic cell cytokine production|down-regulation of myeloid dendritic cell cytokine production													biological_process											owl:Class	
GO:0060726	biolink:NamedThing	regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.	got7fsn_ti	regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway|regulation of Neu/ErbB-2 receptor activity						dph	2009-06-12T01:25:20Z						biological_process											owl:Class	
GO:1900988	biolink:NamedThing	ajmaline biosynthetic process	The chemical reactions and pathways resulting in the formation of ajmaline.	got7fsn_ti	ajmaline synthesis|ajmaline anabolism|ajmaline formation|ajmaline biosynthesis						yaf	2012-06-14T09:47:33Z						biological_process											owl:Class	
GO:1903003	biolink:NamedThing	positive regulation of protein deubiquitination	Any process that activates or increases the frequency, rate or extent of protein deubiquitination.	got7fsn_ti	activation of protein deubiquitination|up regulation of protein deubiquitinylation|activation of protein deubiquitylation|positive regulation of protein deubiquitinylation|activation of protein deubiquitinylation|up-regulation of protein deubiquitylation|upregulation of deubiquitination|up regulation of protein deubiquitination|activation of deubiquitination|positive regulation of deubiquitination|up regulation of deubiquitination|up-regulation of protein deubiquitination|up-regulation of protein deubiquitinylation|upregulation of protein deubiquitinylation|up regulation of protein deubiquitylation|upregulation of protein deubiquitination|positive regulation of protein deubiquitylation|up-regulation of deubiquitination|upregulation of protein deubiquitylation						bf	2014-05-12T15:39:10Z						biological_process											owl:Class	
GO:1904202	biolink:NamedThing	negative regulation of iodide transport	Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport.	got7fsn_ti	downregulation of iodide transport|down-regulation of iodide transport|down regulation of iodide transport|inhibition of iodide transport						sl	2015-05-08T15:20:03Z						biological_process											owl:Class	
GO:0019011	biolink:NamedThing	obsolete DNA replication accessory factor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DNA replication accessory factor				This term was made obsolete because it does not represent a true molecular function.	GO:0006260				True				molecular_function											owl:Class	
GO:1905024	biolink:NamedThing	regulation of membrane repolarization during ventricular cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.	got7fsn_ti	regulation of electrocardiogram T wave|regulation of ventricular repolarization|regulation of regulation of ventricular cardiac muscle repolarization						rph	2016-03-04T11:19:02Z						biological_process											owl:Class	
CHEBI:58360	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000497	biolink:NamedThing	positive regulation of cell proliferation involved in compound eye morphogenesis	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.	got7fsn_ti							bf	2011-03-18T02:19:54Z						biological_process											owl:Class	
GO:1902257	biolink:NamedThing	negative regulation of apoptotic process involved in outflow tract morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.	got7fsn_ti	downregulation of apoptosis involved in outflow tract morphogenesis|down regulation of apoptotic process involved in outflow tract morphogenesis|down-regulation of apoptotic process involved in outflow tract morphogenesis|inhibition of apoptotic process involved in outflow tract morphogenesis|down-regulation of apoptosis involved in outflow tract morphogenesis|downregulation of apoptotic process involved in outflow tract morphogenesis|inhibition of apoptosis involved in outflow tract morphogenesis|negative regulation of apoptosis involved in outflow tract morphogenesis|down regulation of apoptosis involved in outflow tract morphogenesis						dph	2013-06-24T19:12:30Z						biological_process											owl:Class	
GO:0038079	biolink:NamedThing	obsolete MAP kinase activity involved in osmosensory signaling pathway	OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.	got7fsn_ti	MAP kinase activity involved in osmosensory signalling pathway|MAPK activity involved in osmosensory signaling pathway				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:41:31Z		True				molecular_function											owl:Class	
GO:1905201	biolink:NamedThing	gibberellin transmembrane transporter activity	Enables the transfer of gibberellin from one side of a membrane to the other.	got7fsn_ti							lr	2016-05-12T18:20:13Z						molecular_function											owl:Class	
GO:0070376	biolink:NamedThing	regulation of ERK5 cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.	got7fsn_ti	regulation of BMK cascade|regulation of BMK signalling pathway|regulation of ERK5 signaling pathway|regulation of BMK signaling pathway|regulation of BMK1 cascade|regulation of MAPK7 cascade													biological_process											owl:Class	
UBERON:0001769	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902999	biolink:NamedThing	negative regulation of phospholipid efflux	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux.	got7fsn_ti	down regulation of phospholipid export|down-regulation of phospholipid efflux|downregulation of phospholipid export|negative regulation of phospholipid export|inhibition of phospholipid efflux|downregulation of phospholipid efflux|inhibition of phospholipid export|down-regulation of phospholipid export|down regulation of phospholipid efflux						sjp	2014-05-09T08:09:59Z						biological_process											owl:Class	
GO:0030578	biolink:NamedThing	PML body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).	got7fsn_ti	PML body organisation|PML body organization and biogenesis				See also the cellular component term 'PML body ; GO:0016605'.									biological_process											owl:Class	
GO:1905942	biolink:NamedThing	regulation of formation of growth cone in injured axon	Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon.	got7fsn_ti							rz	2017-02-13T09:09:05Z						biological_process											owl:Class	
GO:0008570	biolink:NamedThing	obsolete myosin ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by myosin that provides the energy for actomyosin contraction.	got7fsn_ti	myosin ATPase activity			GO:0000146	This term was made obsolete because it represents a class of gene products, and its definition incorporates process information.	GO:0030048				True				molecular_function											owl:Class	
GO:0018779	biolink:NamedThing	obsolete 2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity				This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.					True				molecular_function											owl:Class	
GO:1901402	biolink:NamedThing	negative regulation of tetrapyrrole metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.	got7fsn_ti	downregulation of tetrapyrrole metabolism|negative regulation of tetrapyrrole metabolism|down regulation of tetrapyrrole metabolism|down regulation of tetrapyrrole metabolic process|inhibition of tetrapyrrole metabolic process|inhibition of tetrapyrrole metabolism|downregulation of tetrapyrrole metabolic process|down-regulation of tetrapyrrole metabolism|down-regulation of tetrapyrrole metabolic process						tt	2012-10-01T14:35:11Z						biological_process											owl:Class	
CHEBI:17020	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052401	biolink:NamedThing	obsolete induction by organism of defense-related symbiont reactive oxygen species production	OBSOLETE. The activation by an organism of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of defense-related symbiont metabolic burst|activation by organism of defense-related symbiont active oxygen species production|induction by organism of defense-related symbiont ROI production|activation by organism of defense-related symbiont reactive oxygen intermediate production|activation by organism of defense-related symbiont oxidative burst|induction by organism of defense-related symbiont oxidative burst|induction by organism of defense-related symbiont reactive oxygen intermediate production|activation by organism of defense-related symbiont reactive oxidative species production|induction by organism of defense-related symbiont AOS production|induction by organism of defense-related symbiont reactive oxygen species production|activation by organism of defense-related symbiont AOS production|induction by organism of defense-related symbiont ROS production|induction by organism of defense-related symbiont metabolic burst|activation by organism of defense-related symbiont reactive oxygen species production|induction by organism of defense-related symbiont active oxygen species production|induction by organism of defense-related symbiont respiratory burst|activation by organism of defense-related symbiont ROI production|activation by organism of defense-related symbiont ROS production|activation by organism of defense-related symbiont respiratory burst				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1904939	biolink:NamedThing	regulation of DNA nucleotidylexotransferase activity	Any process that modulates the frequency, rate or extent of DNA nucleotidylexotransferase activity.	got7fsn_ti	regulation of deoxyribonucleic acid nucleotidyltransferase activity|regulation of terminal deoxyribonucleotidyltransferase activity|regulation of TdT|regulation of terminal transferase activity|regulation of deoxyribonucleic nucleotidyltransferase activity|regulation of terminal addition enzyme activity|regulation of terminal deoxynucleotidyltransferase activity|regulation of terminal deoxynucleotide transferase activity|regulation of deoxynucleotidyl terminal transferase activity|regulation of addase activity|regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity						bc	2016-02-02T15:15:57Z						biological_process											owl:Class	
GO:0005072	biolink:NamedThing	obsolete transforming growth factor beta receptor, cytoplasmic mediator activity	OBSOLETE. Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytoplasm to the nucleus.	got7fsn_ti	TGFbeta receptor, cytoplasmic mediator activity|TGF-beta receptor, cytoplasmic mediator activity	https://github.com/geneontology/go-ontology/issues/16202			This term was obsoleted because it is redundant with other terms.	GO:0000981				True				molecular_function											owl:Class	
GO:2000822	biolink:NamedThing	regulation of behavioral fear response	Any process that modulates the frequency, rate or extent of behavioral fear response.	got7fsn_ti	regulation of behavioural fear response						rl	2011-07-14T04:50:47Z						biological_process											owl:Class	
GO:0050646	biolink:NamedThing	5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Binding to 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.	got7fsn_ti	5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid binding													molecular_function											owl:Class	
GO:1901599	biolink:NamedThing	(-)-pinoresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-pinoresinol.	got7fsn_ti	(-)-pinoresinol anabolism|(-)-pinoresinol synthesis|(-)-pinoresinol formation|(-)-pinoresinol biosynthesis						tb	2012-11-08T01:16:05Z						biological_process											owl:Class	
CHEBI:27445	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043893	biolink:NamedThing	acetate:cation symporter activity	Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).	got7fsn_ti	cation/acetate symporter activity|acetate/cation symporter activity|cation-acetate symporter activity|cation:acetate symporter activity|acetate-cation symporter activity|ActP|acetate permease													molecular_function											owl:Class	
GO:1902819	biolink:NamedThing	ethyl acetate biosynthetic process	The chemical reactions and pathways resulting in the formation of ethyl acetate.	got7fsn_ti	ethyl ethanoate biosynthetic process|ethyl acetate synthesis|ethyl acetate formation|ethyl acetate anabolism|ethyl acetate biosynthesis						tt	2014-03-30T20:26:53Z						biological_process											owl:Class	
GO:1904540	biolink:NamedThing	positive regulation of glycolytic process through fructose-6-phosphate	Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.	got7fsn_ti	up-regulation of glycolytic process through fructose-6-phosphate|upregulation of glycolytic process through fructose-6-phosphate|activation of glycolysis through fructose-6-phosphate|up regulation of glycolytic process through fructose-6-phosphate|upregulation of glycolysis through fructose-6-phosphate|activation of glycolytic process through fructose-6-phosphate|up-regulation of glycolysis through fructose-6-phosphate|up regulation of glycolysis through fructose-6-phosphate|positive regulation of glycolysis through fructose-6-phosphate						dph	2015-08-07T11:35:22Z						biological_process											owl:Class	
GO:0046302	biolink:NamedThing	2-chloro-N-isopropylacetanilide catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.	got7fsn_ti	2-chloro-N-isopropylacetanilide breakdown|2-chloro-N-isopropylacetanilide catabolism|2-chloro-N-isopropylacetanilide degradation													biological_process											owl:Class	
GO:0036102	biolink:NamedThing	leukotriene B4 metabolic process	The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.	got7fsn_ti	LTB4 metabolism						bf	2012-01-27T01:39:43Z						biological_process											owl:Class	
GO:0032015	biolink:NamedThing	regulation of Ran protein signal transduction	Any process that modulates the frequency, rate or extent of Ran protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:0015064	biolink:NamedThing	obsolete UV-sensitive opsin	OBSOLETE. An opsin with maximal absorption below 400 nm.	got7fsn_ti	UV-sensitive opsin				This term was made obsolete because it refers to a class of proteins.	GO:0016918|GO:0009881|GO:0046876|GO:0007604|GO:0016021				True				molecular_function											owl:Class	
GO:0051193	biolink:NamedThing	obsolete regulation of cofactor metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.	got7fsn_ti	regulation of cofactor metabolism				1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True				biological_process											owl:Class	
GO:0086040	biolink:NamedThing	sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential	Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential.	got7fsn_ti	sodium:hydrogen antiporter activity involved in regulation of cardiac muscle cell membrane potential						tb	2011-11-11T03:33:44Z						molecular_function											owl:Class	
GO:1904572	biolink:NamedThing	negative regulation of mRNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding.	got7fsn_ti	downregulation of mRNA binding|down regulation of mRNA binding|inhibition of mRNA binding|down-regulation of mRNA binding						sl	2015-08-19T17:51:03Z						biological_process											owl:Class	
GO:0048039	biolink:NamedThing	ubiquinone binding	Binding to ubiquinone, a quinone derivative with a tail of isoprene units.	got7fsn_ti	coenzyme Q6 binding|coenzyme Q binding													molecular_function											owl:Class	
GO:0100036	biolink:NamedThing	obsolete positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates purine nucleotide biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0048841	biolink:NamedThing	regulation of axon extension involved in axon guidance	Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.	got7fsn_ti														biological_process											owl:Class	
GO:1904311	biolink:NamedThing	response to gold(3+)	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.	got7fsn_ti							sl	2015-06-10T17:41:07Z						biological_process											owl:Class	
GO:0015260	biolink:NamedThing	obsolete isethionate channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	isethionate channel activity				This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True				molecular_function											owl:Class	
CHEBI:30854	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006675	biolink:NamedThing	mannosyl-inositol phosphorylceramide metabolic process	The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.	got7fsn_ti	MIPC metabolism|mannose-inositol-P-ceramide (MIPC) metabolism|mannose-inositol-P-ceramide (MIPC) metabolic process|mannosyl-inositol-phosphorylceramide metabolism|MIPC metabolic process|mannose inositol phosphoceramide metabolic process|mannose inositol phosphoceramide metabolism													biological_process											owl:Class	
GO:0038056	biolink:NamedThing	negative regulation of BMP signaling pathway by negative regulation of BMP secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell.	got7fsn_ti	negative regulation of BMP signalling pathway by negative regulation of BMP secretion|negative regulation of BMP signaling pathway by negative regulation of bone morphogenetic protein secretion						bf	2011-12-19T10:55:47Z						biological_process											owl:Class	
GO:1901623	biolink:NamedThing	regulation of lymphocyte chemotaxis	Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.	got7fsn_ti							tb	2012-11-13T23:03:23Z						biological_process											owl:Class	
GO:0072352	biolink:NamedThing	tricarboxylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.	got7fsn_ti	tricarboxylic acid degradation|tricarboxylate catabolic process|tricarboxylic acid breakdown|tricarboxylate catabolism|tricarboxylic acid catabolism						mah	2010-11-11T05:11:24Z						biological_process											owl:Class	
GO:0008042	biolink:NamedThing	obsolete iron-sulfur electron transfer carrier	OBSOLETE. An iron-sulfur protein that serves as an electron acceptor and electron donor in an electron transport system.	got7fsn_ti	iron-sulphur electron transfer carrier|iron-sulfur electron transfer carrier|ferredoxin			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:0040006	biolink:NamedThing	obsolete protein-based cuticle attachment to epithelium	OBSOLETE. Attaching of a protein-based cuticle to the epithelium underlying it.	got7fsn_ti	cuticular attachment to epithelium|protein-based cuticle attachment to epithelium				This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0040004|GO:0040005				True				biological_process											owl:Class	
GO:2000340	biolink:NamedThing	positive regulation of chemokine (C-X-C motif) ligand 1 production	Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.	got7fsn_ti	positive regulation of keratinocyte derived chemokine production|positive regulation of SCYB1 production|positive regulation of CXCL1 production|positive regulation of KC production						mah	2011-02-01T10:46:33Z						biological_process											owl:Class	
GO:1901658	biolink:NamedThing	glycosyl compound catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosyl compound.	got7fsn_ti	glycosyl compound degradation|glycosyl compound catabolism|glycosyl compound breakdown						pr	2012-11-20T14:24:11Z						biological_process											owl:Class	
GO:0090228	biolink:NamedThing	positive regulation of red or far-red light signaling pathway	Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.	got7fsn_ti	positive regulation of red or far-red light signalling pathway|positive regulation of phytochrome signaling pathway						tb	2010-01-19T04:03:29Z						biological_process											owl:Class	
GO:0080036	biolink:NamedThing	regulation of cytokinin-activated signaling pathway	Any process that modulates the frequency, rate or extent of cytokinin signaling.	got7fsn_ti	regulation of cytokinin mediated signaling pathway|regulation of cytokinin mediated signalling													biological_process											owl:Class	
GO:1905943	biolink:NamedThing	negative regulation of formation of growth cone in injured axon	Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon.	got7fsn_ti	down-regulation of formation of growth cone in injured axon|downregulation of formation of growth cone in injured axon|down regulation of formation of growth cone in injured axon|inhibition of formation of growth cone in injured axon						rz	2017-02-13T09:09:13Z						biological_process											owl:Class	
GO:0075103	biolink:NamedThing	obsolete modulation by host of symbiont calcium or calmodulin-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by host of symbiont Ca++ or calmodulin-mediated signal transduction				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:1903973	biolink:NamedThing	negative regulation of cellular response to macrophage colony-stimulating factor stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.	got7fsn_ti	down-regulation of cellular response to M-CSF stimulus|down regulation of cellular response to M-CSF stimulus|inhibition of cellular response to macrophage colony-stimulating factor stimulus|down-regulation of cellular response to macrophage colony-stimulating factor|inhibition of cellular response to M-CSF stimulus|negative regulation of cellular response to M-CSF stimulus|inhibition of cellular response to macrophage colony-stimulating factor|downregulation of cellular response to macrophage colony-stimulating factor|down regulation of cellular response to macrophage colony-stimulating factor|downregulation of cellular response to macrophage colony-stimulating factor stimulus|negative regulation of cellular response to macrophage colony-stimulating factor|down regulation of cellular response to macrophage colony-stimulating factor stimulus|down-regulation of cellular response to macrophage colony-stimulating factor stimulus|downregulation of cellular response to M-CSF stimulus						nc	2015-03-02T14:50:20Z						biological_process											owl:Class	
GO:1901743	biolink:NamedThing	2-deoxystreptamine catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine.	got7fsn_ti	2-deoxystreptamine breakdown|2-deoxystreptamine catabolism|2-deoxystreptamine degradation						yaf	2013-01-14T10:02:01Z						biological_process											owl:Class	
GO:0042643	biolink:NamedThing	obsolete actomyosin, actin portion	OBSOLETE. The actin part of any complex of actin, myosin, and accessory proteins.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19570			This term was obsoleted because it corresponds to a gene product, actin.					True				cellular_component											owl:Class	
GO:1903484	biolink:NamedThing	obsolete negative regulation of maintenance of mitotic actomyosin contractile ring localization	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.	got7fsn_ti	down-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|downregulation of cytokinetic ring anchoring involved in mitotic cell cycle|down regulation of cytokinetic ring anchoring involved in mitotic cell cycle|inhibition of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of maintenance of mitotic actomyosin contractile ring localization|downregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of maintenance of mitotic actomyosin contractile ring localization|down-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|down regulation of maintenance of mitotic actomyosin contractile ring localization|down regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|negative regulation of cytokinetic ring anchoring involved in mitotic cell cycle|inhibition of maintenance of mitotic actomyosin contractile ring localization|down-regulation of cytokinetic ring anchoring involved in mitotic cell cycle|inhibition of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of cytokinetic ring anchoring involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle				The reason for obsoletion is that this term represents a GO-CAM model.		vw	2014-09-23T16:12:28Z		True				biological_process											owl:Class	
GO:0015053	biolink:NamedThing	obsolete opsin	OBSOLETE. Hydrophobic glycoprotein to which 11-cis-retinal binds as a Schiff base (in rhodopsin) or 3,4-didehydro-11-cis-retinal binds as a Schiff base in cyanopsin and porphyropsin.	got7fsn_ti	opsin				This term was made obsolete because it refers to a class of proteins.	GO:0016021|GO:0016918|GO:0009881|GO:0007602|GO:0046876				True				molecular_function											owl:Class	
GO:0032965	biolink:NamedThing	regulation of collagen biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	got7fsn_ti	regulation of collagen biosynthesis|regulation of collagen formation|regulation of collagen anabolism|regulation of collagen synthesis													biological_process											owl:Class	
GO:1903877	biolink:NamedThing	21-deoxycortisol binding	Binding to 21-deoxycortisol.	got7fsn_ti							mr	2015-02-06T16:02:54Z						molecular_function											owl:Class	
GO:0070300	biolink:NamedThing	phosphatidic acid binding	Binding to phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.	got7fsn_ti	phosphatidate binding													molecular_function											owl:Class	
GO:0015281	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043788	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032816	biolink:NamedThing	positive regulation of natural killer cell activation	Any process that activates or increases the frequency, rate or extent of natural killer cell activation.	got7fsn_ti	upregulation of natural killer cell activation|positive regulation of NK cell activation|up regulation of natural killer cell activation|up-regulation of natural killer cell activation|stimulation of natural killer cell activation|activation of natural killer cell activation													biological_process											owl:Class	
GO:0045221	biolink:NamedThing	negative regulation of FasL production	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.	got7fsn_ti	downregulation of FasL biosynthetic process|down-regulation of FasL biosynthetic process|negative regulation of FasL formation|negative regulation of FasL biosynthesis|down regulation of FasL biosynthetic process|inhibition of FasL biosynthetic process|negative regulation of FasL anabolism|negative regulation of FasL synthesis|negative regulation of FasL biosynthetic process													biological_process											owl:Class	
GO:0019584	biolink:NamedThing	galactonate catabolic process	The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid.	got7fsn_ti	galactonate breakdown|galactonate degradation|galactonate catabolism											MetaCyc:GALACTCAT-PWY		biological_process											owl:Class	
GO:0010804	biolink:NamedThing	negative regulation of tumor necrosis factor-mediated signaling pathway	Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.	got7fsn_ti	negative regulation of TNF signaling|negative regulation of TNF-mediated signaling pathway|negative regulation of tumor necrosis factor-mediated signalling pathway													biological_process											owl:Class	
GO:1902101	biolink:NamedThing	positive regulation of metaphase/anaphase transition of cell cycle	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle.	got7fsn_ti	up regulation of metaphase/anaphase transition of cell cycle|up-regulation of metaphase/anaphase transition of cell cycle|activation of metaphase/anaphase transition of cell cycle|upregulation of metaphase/anaphase transition of cell cycle						jl	2013-05-02T12:45:30Z						biological_process											owl:Class	
GO:0075216	biolink:NamedThing	positive regulation of spore encystment on host	Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0072317	biolink:NamedThing	obsolete glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus	OBSOLETE. Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans that contributes to the release of ascospores from the ascus.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15204			This term was obsoleted because it should be captured as a GO-CAM model.		mah	2010-10-25T05:46:13Z		True				molecular_function											owl:Class	
GO:0061095	biolink:NamedThing	positive regulation of turning behavior involved in mating	Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.	got7fsn_ti							dph	2010-04-26T02:12:24Z						biological_process											owl:Class	
GO:0045780	biolink:NamedThing	positive regulation of bone resorption	Any process that activates or increases the frequency, rate or extent of bone resorption.	got7fsn_ti	up regulation of bone resorption|activation of bone resorption|up-regulation of bone resorption|upregulation of bone resorption|stimulation of bone resorption													biological_process											owl:Class	
GO:0070507	biolink:NamedThing	regulation of microtubule cytoskeleton organization	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.	got7fsn_ti	regulation of microtubule dynamics|regulation of microtubule cytoskeleton organisation													biological_process											owl:Class	
GO:1900430	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms.	got7fsn_ti	up regulation of filamentous growth of a population of unicellular organisms|upregulation of filamentous growth of a population of unicellular organisms|activation of filamentous growth of a population of unicellular organisms|up-regulation of filamentous growth of a population of unicellular organisms						di	2012-04-25T05:53:52Z						biological_process											owl:Class	
GO:1903291	biolink:NamedThing	obsolete positive regulation of ATP catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP catabolic process.	got7fsn_ti	upregulation of ATP catabolism|up-regulation of ATP hydrolysis|activation of ATP catabolism|positive regulation of ATP breakdown|up regulation of ATP hydrolysis|activation of ATP breakdown|up regulation of ATP catabolism|up-regulation of ATP catabolic process|upregulation of ATP degradation|positive regulation of ATP degradation|up-regulation of ATP breakdown|up-regulation of ATP catabolism|up regulation of ATP degradation|activation of ATP catabolic process|positive regulation of ATP hydrolysis|upregulation of ATP hydrolysis|activation of ATP hydrolysis|up regulation of ATP catabolic process|up-regulation of ATP degradation|positive regulation of ATP catabolism|upregulation of ATP catabolic process|up regulation of ATP breakdown|upregulation of ATP breakdown|activation of ATP degradation				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0032781	rl	2014-08-11T14:36:55Z		True				biological_process											owl:Class	
GO:0062161	biolink:NamedThing	regulation of pyocyanine biosynthetic process	Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process.	got7fsn_ti	regulation of pyocyanin biosynthetic process						dph	2019-11-06T14:36:27Z						biological_process											owl:Class	
GO:0044126	biolink:NamedThing	obsolete regulation of growth of symbiont in host	OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T02:10:08Z		True				biological_process											owl:Class	
GO:0010581	biolink:NamedThing	regulation of starch biosynthetic process	An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch.	got7fsn_ti														biological_process											owl:Class	
GO:0098740	biolink:NamedThing	obsolete multi organism cell adhesion	OBSOLETE. Cell adhesion that involves cells from multiple organisms or that is mediated by gene products from multiple organisms.	got7fsn_ti					This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0006077	biolink:NamedThing	(1->6)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds.	got7fsn_ti	beta-1,6 glucan metabolic process|1,6-beta-glucan metabolism|1,6-beta-glucan metabolic process|beta-1,6 glucan metabolism													biological_process											owl:Class	
GO:1905484	biolink:NamedThing	negative regulation of motor neuron migration	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration.	got7fsn_ti	down regulation of motor neuron migration|downregulation of motor neuron migration|down-regulation of motor neuron migration|inhibition of motor neuron migration						hbye	2016-09-23T12:50:11Z						biological_process											owl:Class	
GO:0050980	biolink:NamedThing	detection of light stimulus involved in magnetoreception	The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field.	got7fsn_ti	magnetoreception, sensory transduction of light stimulus|magnetoreception, detection of light stimulus|sensory transduction of light stimulus during magnetoreception|sensory detection of light stimulus during magnetoreception|magnetoreception, sensory detection of light stimulus													biological_process											owl:Class	
CL:1000143	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150036	biolink:NamedThing	regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission	Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		bc	2018-04-18T09:54:49Z						biological_process											owl:Class	
GO:0051144	biolink:NamedThing	propanediol catabolic process	The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.	got7fsn_ti	1,2-dihydroxypropane catabolism|propylene glycol catabolism|1,2-dihydroxypropane catabolic process|propanediol degradation|propanediol breakdown|propanediol catabolism|propylene glycol catabolic process													biological_process											owl:Class	
GO:0009156	biolink:NamedThing	ribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	ribonucleoside monophosphate formation|ribonucleoside monophosphate anabolism|ribonucleoside monophosphate synthesis|ribonucleoside monophosphate biosynthesis													biological_process											owl:Class	
GO:0043567	biolink:NamedThing	regulation of insulin-like growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling.	got7fsn_ti	regulation of insulin-like growth factor receptor signalling pathway|regulation of IGF receptor signaling pathway|regulation of IGF receptor signalling pathway													biological_process											owl:Class	
GO:0005482	biolink:NamedThing	obsolete vesicle targeting	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	vesicle targeting				This term was made obsolete because it represents a biological process and not a molecular function.	GO:0006903|GO:0016080				True				molecular_function											owl:Class	
GO:1901442	biolink:NamedThing	regulation of response to furfural	Any process that modulates the frequency, rate or extent of response to furfural.	got7fsn_ti							tt	2012-10-02T14:09:26Z						biological_process											owl:Class	
GO:0062103	biolink:NamedThing	double-stranded RNA biosynthetic process	The chemical reactions and pathways resulting in the formation of double-stranded RNA.	got7fsn_ti	dsRNA biosynthesis|double-stranded RNA biosynthesis|dsRNA biosynthetic process						dph	2019-01-07T13:29:47Z						biological_process											owl:Class	
GO:1905443	biolink:NamedThing	regulation of clathrin coat assembly	Any process that modulates the frequency, rate or extent of clathrin coat assembly.	got7fsn_ti	regulation of clathrin cage assembly						bf	2016-09-15T14:38:22Z						biological_process											owl:Class	
GO:0090190	biolink:NamedThing	positive regulation of branching involved in ureteric bud morphogenesis	Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	got7fsn_ti							tb	2009-12-18T11:11:17Z						biological_process											owl:Class	
GO:0062108	biolink:NamedThing	negative regulation of protein localization to non-growing cell tip	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip.	got7fsn_ti							dph	2019-02-05T13:03:52Z						biological_process											owl:Class	
GO:0030202	biolink:NamedThing	heparin metabolic process	The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.	got7fsn_ti	heparin metabolism|heparan sulfate metabolic process													biological_process											owl:Class	
GO:1902235	biolink:NamedThing	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.	got7fsn_ti	regulation of apoptosis triggered by ER stress|regulation of endoplasmic reticulum stress-induced apoptosis|regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of apoptosis in response to ER stress|regulation of apoptosis in response to endoplasmic reticulum stress|regulation of ER stress-induced apoptosis						rl	2013-06-18T15:19:37Z						biological_process											owl:Class	
GO:1990951	biolink:NamedThing	obsolete manchette assembly	OBSOLETE. The assembly and organization of the manchette, a tubular array of microtubules, possibly also containing actin filaments, that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		krc	2016-05-11T00:05:35Z		True				biological_process											owl:Class	
GO:0051152	biolink:NamedThing	positive regulation of smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.	got7fsn_ti	up-regulation of smooth muscle cell differentiation|activation of smooth muscle cell differentiation|stimulation of smooth muscle cell differentiation|upregulation of smooth muscle cell differentiation|up regulation of smooth muscle cell differentiation													biological_process											owl:Class	
GO:0008638	biolink:NamedThing	obsolete protein tagging activity	OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e.g. degradation.	got7fsn_ti	protein tagging activity				This term was made obsolete because it represents a biological process and a molecular function.	GO:0006464|GO:0031386|GO:0005515				True				molecular_function											owl:Class	
GO:0038077	biolink:NamedThing	obsolete MAP kinase kinase kinase activity involved in innate immune response	OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to an innate immune response.	got7fsn_ti	MAPKKK activity involved in innate immune response|MAP3K activity involved in innate immune response				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:35:52Z		True				molecular_function											owl:Class	
GO:1903521	biolink:NamedThing	positive regulation of mammary gland involution	Any process that activates or increases the frequency, rate or extent of mammary gland involution.	got7fsn_ti	activation of mammary gland involution|upregulation of mammary gland involution|up-regulation of mammary gland involution|up regulation of mammary gland involution						dph	2014-10-06T12:01:39Z						biological_process											owl:Class	
GO:0001798	biolink:NamedThing	positive regulation of type IIa hypersensitivity	Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response.	got7fsn_ti	upregulation of type IIa hypersensitivity|up regulation of type IIa hypersensitivity|up-regulation of type IIa hypersensitivity|activation of type IIa hypersensitivity|stimulation of type IIa hypersensitivity													biological_process											owl:Class	
GO:0034095	biolink:NamedThing	negative regulation of maintenance of meiotic sister chromatid cohesion	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
CHEBI:58759	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045297	biolink:NamedThing	obsolete post-mating behavior	OBSOLETE. The specific behavior of an organism following mating.	got7fsn_ti	post-mating behaviour				This term was obsoleted because it was not precisely defined.					True				biological_process											owl:Class	
GO:1905390	biolink:NamedThing	cellular response to leukotriene B4	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.	got7fsn_ti	cellular response to LTB4						sl	2016-08-18T16:37:31Z						biological_process											owl:Class	
GO:1901833	biolink:NamedThing	all-trans-neoxanthin biosynthetic process	The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin.	got7fsn_ti	all-trans-neoxanthin synthesis|neoxanthin formation|all-trans-neoxanthin formation|neoxanthin synthesis|neoxanthin biosynthesis|all-trans-neoxanthin biosynthesis|neoxanthin anabolism|neoxanthin biosynthetic process|all-trans-neoxanthin anabolism						yaf	2013-01-22T12:43:56Z						biological_process											owl:Class	
GO:2000447	biolink:NamedThing	negative regulation of macrophage migration inhibitory factor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.	got7fsn_ti	negative regulation of MIF signaling pathway|negative regulation of macrophage migration inhibitory factor signalling pathway						bf	2011-03-04T10:38:15Z						biological_process											owl:Class	
GO:1902647	biolink:NamedThing	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.	got7fsn_ti	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism						di	2014-01-21T17:58:06Z						biological_process											owl:Class	
GO:1904449	biolink:NamedThing	negative regulation of aspartate secretion	Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion.	got7fsn_ti	down-regulation of aspartate secretion|inhibition of aspartate secretion|down regulation of aspartate secretion|downregulation of aspartate secretion						sl	2015-07-07T20:57:04Z						biological_process											owl:Class	
GO:2000974	biolink:NamedThing	negative regulation of pro-B cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.	got7fsn_ti	negative regulation of pro-B lymphocyte differentiation|negative regulation of pro-B cell development						yaf	2011-08-02T03:05:50Z						biological_process											owl:Class	
GO:1903111	biolink:NamedThing	negative regulation of single-strand break repair via homologous recombination	Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination.	got7fsn_ti	down-regulation of single-strand break repair via homologous recombination|down regulation of single-strand break repair via homologous recombination|downregulation of single-strand break repair via homologous recombination|inhibition of single-strand break repair via homologous recombination						pr	2014-06-09T12:11:32Z						biological_process											owl:Class	
GO:0032831	biolink:NamedThing	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.	got7fsn_ti	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1903460	biolink:NamedThing	mitotic DNA replication leading strand elongation	Any leading strand elongation that is involved in mitotic cell cycle DNA replication.	got7fsn_ti	leading strand elongation involved in mitotic DNA replication|leading strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|leading strand elongation involved in mitotic nuclear cell cycle DNA replication|leading strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle|leading strand elongation involved in DNA replication during S phase involved in mitotic cell cycle|leading strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle						vw	2014-09-23T13:33:03Z						biological_process											owl:Class	
GO:0072451	biolink:NamedThing	obsolete detection of stimulus involved in G2 cell size control checkpoint	OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a G2/M transition size control checkpoint.	got7fsn_ti	detection of stimulus involved in mitotic cell cycle G2/M transition size control checkpoint|G2/M transition size control checkpoint sensor process|detection of stimulus involved in G2/M transition size control checkpoint|G2/M transition size control checkpoint sensor mechanism|sensing involved in G2/M transition size control checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:14:00Z		True				biological_process											owl:Class	
GO:1902200	biolink:NamedThing	3-methylbut-2-enoyl-CoA(4-) biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-).	got7fsn_ti	3-methylbut-2-enoyl-CoA(4-) anabolism|3-methylbut-2-enoyl-CoA(4-) synthesis|3-methylbut-2-enoyl-CoA(4-) formation|3-methylbut-2-enoyl-CoA(4-) biosynthesis						ms	2013-06-06T09:56:21Z						biological_process											owl:Class	
GO:0030406	biolink:NamedThing	obsolete matrix metalloproteinase 25 activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	MMP-25|MT6-MMP|matrix metalloproteinase 25 activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0032826	biolink:NamedThing	regulation of natural killer cell differentiation involved in immune response	Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response.	got7fsn_ti	regulation of natural killer cell development involved in immune response|regulation of NK cell differentiation during immune response|regulation of natural killer cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1900111	biolink:NamedThing	positive regulation of histone H3-K9 dimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation.	got7fsn_ti	activation of histone H3-K9 dimethylation|upregulation of histone lysine H3 K9 dimethylation|up-regulation of histone H3 K9 dimethylation|up regulation of histone H3 K9 dimethylation|upregulation of histone H3 K9 dimethylation|positive regulation of histone lysine H3 K9 dimethylation|up regulation of histone lysine H3 K9 dimethylation|activation of histone lysine H3 K9 dimethylation|upregulation of histone H3-K9 dimethylation|positive regulation of histone H3 K9 dimethylation|up-regulation of histone H3-K9 dimethylation|up-regulation of histone lysine H3 K9 dimethylation|activation of histone H3 K9 dimethylation|up regulation of histone H3-K9 dimethylation						bf	2012-02-21T09:06:26Z						biological_process											owl:Class	
GO:0035829	biolink:NamedThing	obsolete renal rubidium ion absorption	OBSOLETE. A renal system process in which rubidium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	got7fsn_ti	renal Rb+ absorption|renal rubidium cation absorption				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-04T03:01:05Z		True				biological_process											owl:Class	
GO:0009412	biolink:NamedThing	obsolete response to heavy metal	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heavy metal stimulus. Heavy metals are those metals that can form a coordination bond with a protein; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	got7fsn_ti	response to heavy metal				This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0010038				True				biological_process											owl:Class	
GO:0072366	biolink:NamedThing	obsolete regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of cellular ketone metabolism by positive regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolic process by positive regulation of transcription from an RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:12:47Z		True				biological_process											owl:Class	
GO:1901328	biolink:NamedThing	response to cytochalasin B	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.	got7fsn_ti							mah	2012-08-30T16:36:35Z						biological_process											owl:Class	
GO:1903144	biolink:NamedThing	actomyosin contractile ring actin filament	Any actin filament that is part of a actomyosin contractile ring.	got7fsn_ti	actin filament of CAR|actin filament of actomyosin contractile ring|actin filament of actomyosin ring|actin filament of contractile actomyosin ring|actin filament of cytokinetic ring						vw	2014-07-06T16:20:05Z						cellular_component											owl:Class	
GO:0005623	biolink:NamedThing	obsolete cell	OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19036	cell and encapsulating structures		This term was obsoleted because it was redundant with the root class of the cell ontology, CL:0000000.					True		NIF_Subcellular:sao1813327414|Wikipedia:Cell_(biology)		cellular_component											owl:Class	
GO:1902793	biolink:NamedThing	glutamate decarboxylase complex	A protein complex which is capable of glutamate decarboxylase activity.	got7fsn_ti					An example of this is GAD1 in human (Q99259) in PMID:17384644 (inferred from direct assay).		bhm	2014-03-24T10:59:45Z						cellular_component											owl:Class	
GO:1901821	biolink:NamedThing	alpha-zeacarotene biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-zeacarotene.	got7fsn_ti	alpha-zeacarotene synthesis|alpha-zeacarotene anabolism|alpha-zeacarotene formation|alpha-zeacarotene biosynthesis						yaf	2013-01-22T10:51:14Z						biological_process											owl:Class	
OBO:GOCHE_33229	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000919	biolink:NamedThing	negative regulation of glucuronoarabinoxylan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process.	got7fsn_ti	negative regulation of glucuronoarabinoxylan catabolism						tt	2011-08-01T12:36:53Z						biological_process											owl:Class	
GO:1904900	biolink:NamedThing	negative regulation of myosin II filament organization	Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization.	got7fsn_ti	downregulation of myosin II filament organization|down regulation of myosin II polymerization or depolymerization|negative regulation of myosin II filament assembly or disassembly|inhibition of myosin II filament organization|inhibition of myosin II filament assembly or disassembly|down-regulation of myosin II filament assembly or disassembly|down-regulation of myosin II polymerization or depolymerization|down regulation of myosin II filament organization|downregulation of myosin II polymerization or depolymerization|down regulation of myosin II filament organisation|inhibition of myosin II filament organisation|negative regulation of myosin II filament organisation|downregulation of myosin II filament assembly or disassembly|downregulation of myosin II filament organisation|down-regulation of myosin II filament organization|inhibition of myosin II polymerization or depolymerization|down-regulation of myosin II filament organisation|negative regulation of myosin II polymerization or depolymerization|down regulation of myosin II filament assembly or disassembly						mec	2016-01-15T09:04:54Z						biological_process											owl:Class	
GO:0019745	biolink:NamedThing	pentacyclic triterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.	got7fsn_ti	pentacyclic triterpenoid formation|pentacyclic triterpenoid synthesis|pentacyclic triterpenoid anabolism|pentacyclic triterpenoid biosynthesis													biological_process											owl:Class	
GO:1901132	biolink:NamedThing	kanamycin catabolic process	The chemical reactions and pathways resulting in the breakdown of kanamycin.	got7fsn_ti	kanamycin degradation|kanamycin catabolism|kanamycin breakdown						yaf	2012-07-11T03:27:24Z						biological_process											owl:Class	
GO:0009417	biolink:NamedThing	obsolete fimbrin	OBSOLETE. A class of proteins that are the subunit components of fimbria.	got7fsn_ti	fimbrin			GO:0009289	This term was made obsolete because it represents a class of gene products.					True				cellular_component											owl:Class	
GO:1903387	biolink:NamedThing	positive regulation of homophilic cell adhesion	Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion.	got7fsn_ti	up-regulation of homophilic cell adhesion|activation of homophilic cell adhesion|up regulation of homophilic cell adhesion|upregulation of homophilic cell adhesion						als	2014-08-27T09:57:46Z						biological_process											owl:Class	
GO:0048181	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904479	biolink:NamedThing	negative regulation of intestinal absorption	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption.	got7fsn_ti	down-regulation of intestinal absorption|inhibition of intestinal absorption|down regulation of intestinal absorption|downregulation of intestinal absorption						rl	2015-07-13T15:58:54Z						biological_process											owl:Class	
GO:0071391	biolink:NamedThing	cellular response to estrogen stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.	got7fsn_ti	cellular response to oestrogen stimulus						mah	2009-12-11T04:09:56Z						biological_process											owl:Class	
GO:1905681	biolink:NamedThing	negative regulation of innate immunity memory response	Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response.	got7fsn_ti	down regulation of innate immunity memory response|downregulation of innate immunity memory response|inhibition of innate immunity memory response|down-regulation of innate immunity memory response						tb	2016-11-11T22:25:29Z						biological_process											owl:Class	
GO:0140161	biolink:NamedThing	monocarboxylate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in).	got7fsn_ti							pg	2018-02-05T10:33:55Z						molecular_function											owl:Class	
GO:0030819	biolink:NamedThing	obsolete positive regulation of cAMP biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	positive regulation of cyclic AMP biosynthesis|positive regulation of adenosine 3',5'-cyclophosphate biosynthetic process|positive regulation of cyclic AMP biosynthetic process|up regulation of cAMP biosynthetic process|positive regulation of cAMP anabolism|upregulation of cAMP biosynthetic process|positive regulation of cAMP synthesis|stimulation of cAMP biosynthetic process|positive regulation of 3',5' cAMP biosynthesis|positive regulation of 3',5'-cAMP biosynthesis|positive regulation of cAMP formation|positive regulation of 3',5'-cAMP biosynthetic process|activation of cAMP biosynthetic process|up-regulation of cAMP biosynthetic process|positive regulation of 3',5' cAMP biosynthetic process|positive regulation of cAMP biosynthesis|positive regulation of adenosine 3',5'-cyclophosphate biosynthesis	https://github.com/geneontology/go-ontology/issues/14718								True				biological_process											owl:Class	
GO:0050862	biolink:NamedThing	positive regulation of T cell receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.	got7fsn_ti	activation of T cell receptor signaling pathway|positive regulation of T lymphocyte receptor signalling pathway|positive regulation of T lymphocyte receptor signaling pathway|upregulation of T cell receptor signaling pathway|positive regulation of T-lymphocyte receptor signalling pathway|stimulation of T cell receptor signaling pathway|positive regulation of T-cell receptor signaling pathway|positive regulation of TCR signaling pathway|up-regulation of T cell receptor signaling pathway|up regulation of T cell receptor signaling pathway|positive regulation of T cell receptor signalling pathway|positive regulation of T-lymphocyte receptor signaling pathway													biological_process											owl:Class	
GO:1903882	biolink:NamedThing	negative regulation of interleukin-17-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway.	got7fsn_ti	negative regulation of interleukin-17-mediated signalling pathway|downregulation of interleukin-17-mediated signaling pathway|down-regulation of IL-17-mediated signalling pathway|downregulation of IL-17-mediated signaling pathway|inhibition of IL-17-mediated signalling pathway|down regulation of interleukin-17-mediated signaling pathway|inhibition of IL-17-mediated signaling pathway|down regulation of interleukin-17-mediated signalling pathway|negative regulation of IL-17-mediated signalling pathway|down-regulation of interleukin-17-mediated signalling pathway|down-regulation of IL-17-mediated signaling pathway|down-regulation of interleukin-17-mediated signaling pathway|negative regulation of IL-17-mediated signaling pathway|inhibition of interleukin-17-mediated signalling pathway|down regulation of IL-17-mediated signalling pathway|down regulation of IL-17-mediated signaling pathway|inhibition of interleukin-17-mediated signaling pathway|downregulation of IL-17-mediated signalling pathway|downregulation of interleukin-17-mediated signalling pathway						krc	2015-02-06T16:26:47Z						biological_process											owl:Class	
GO:1904994	biolink:NamedThing	regulation of leukocyte adhesion to vascular endothelial cell	Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.	got7fsn_ti							bc	2016-03-01T10:59:00Z						biological_process											owl:Class	
GO:0070247	biolink:NamedThing	regulation of natural killer cell apoptotic process	Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process.	got7fsn_ti	regulation of NK cell apoptosis|regulation of natural killer cell apoptosis													biological_process											owl:Class	
GO:1902458	biolink:NamedThing	positive regulation of stomatal opening	Any process that activates or increases the frequency, rate or extent of stomatal opening.	got7fsn_ti	up regulation of stomatal opening|up-regulation of stomatal opening|upregulation of stomatal opening|activation of stomatal opening						tb	2013-10-16T22:25:33Z						biological_process											owl:Class	
GO:1903115	biolink:NamedThing	regulation of actin filament-based movement	Any process that modulates the frequency, rate or extent of actin filament-based movement.	got7fsn_ti							al	2014-06-12T16:55:57Z						biological_process											owl:Class	
GO:0052050	biolink:NamedThing	obsolete interaction with host via substance secreted by type IV secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type IV secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0006918	biolink:NamedThing	obsolete induction of apoptosis by p53	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	induction of apoptosis by p53				This term was made obsolete because more accurate terms were created.	GO:0006915				True				biological_process											owl:Class	
GO:0005366	biolink:NamedThing	myo-inositol:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in).	got7fsn_ti	hydrogen/myo-inositol transporter activity|myo-inositol:hydrogen symporter activity											Reactome:R-HSA-429101|RHEA:60364		molecular_function											owl:Class	
GO:0046100	biolink:NamedThing	hypoxanthine metabolic process	The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.	got7fsn_ti	hypoxanthine metabolism													biological_process											owl:Class	
GO:1902294	biolink:NamedThing	cell cycle DNA replication termination	Any DNA replication termination that is involved in cell cycle DNA replication.	got7fsn_ti	DNA replication termination involved in cell cycle DNA replication						jl	2013-07-09T16:06:11Z						biological_process											owl:Class	
GO:1902370	biolink:NamedThing	regulation of tRNA catabolic process	Any process that modulates the frequency, rate or extent of tRNA catabolic process.	got7fsn_ti	regulation of tRNA breakdown|regulation of tRNA catabolism|regulation of tRNA degradation						bf	2013-08-22T15:08:12Z						biological_process											owl:Class	
GO:0071873	biolink:NamedThing	response to norepinephrine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.	got7fsn_ti	response to noradrenaline stimulus|response to norepinephrine stimulus				Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.		mah	2010-09-13T03:31:53Z						biological_process											owl:Class	
GO:0006744	biolink:NamedThing	ubiquinone biosynthetic process	The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.	got7fsn_ti	coenzyme Q9 biosynthetic process|coenzyme Q8 biosynthetic process|ubiquinone formation|ubiquinone synthesis|ubiquinone biosynthesis|coenzyme Q10 biosynthesis|coenzyme Q10 biosynthetic process|coenzyme Q biosynthesis|coenzyme Q biosynthetic process|ubiquinone anabolism|coenzyme Q9 biosynthesis|coenzyme Q6 biosynthetic process|coenzyme Q6 biosynthesis|coenzyme Q8 biosynthesis											MetaCyc:UBISYN-PWY		biological_process											owl:Class	
GO:0075049	biolink:NamedThing	obsolete modulation of symbiont cell wall strengthening involved in entry into host	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of symbiont cell wall strengthening during entry into host				The reason for the obsoletion is that there is no evidence that those processes exist.					True				biological_process											owl:Class	
GO:0015665	biolink:NamedThing	alcohol transmembrane transporter activity	Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.	got7fsn_ti														molecular_function											owl:Class	
GO:2000257	biolink:NamedThing	regulation of protein activation cascade	Any process that modulates the frequency, rate or extent of protein activation cascade.	got7fsn_ti	regulation of protein activation pathway|regulation of protein activitory cascade						mah	2010-11-23T11:33:46Z						biological_process											owl:Class	
GO:0015427	biolink:NamedThing	obsolete ABC-type efflux porter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ABC-type efflux porter activity				This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.	GO:0042626|GO:0043190				True				molecular_function											owl:Class	
GO:0099095	biolink:NamedThing	ligand-gated anion channel activity	Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0017142	biolink:NamedThing	obsolete toxin susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	toxin susceptibility/resistance			GO:0009636	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0052146	biolink:NamedThing	obsolete positive energy taxis on or near host	OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0052471	biolink:NamedThing	obsolete modulation by organism of systemic acquired resistance in symbiont	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of systemic acquired resistance in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
CHEBI:65321	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903124	biolink:NamedThing	negative regulation of thioredoxin peroxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity.	got7fsn_ti	down-regulation of TPx activity|inhibition of thioredoxin peroxidase activity|downregulation of thioredoxin peroxidase activity|down regulation of thiol peroxidase activity|negative regulation of TPx activity|downregulation of thiol peroxidase activity|down-regulation of thiol peroxidase activity|negative regulation of thiol peroxidase activity|downregulation of TPx activity|inhibition of TPx activity|down-regulation of thioredoxin peroxidase activity|down regulation of thioredoxin peroxidase activity|inhibition of thiol peroxidase activity|down regulation of TPx activity|down regulation of TrxPx activity|negative regulation of TrxPx activity|inhibition of TrxPx activity|down-regulation of TrxPx activity|downregulation of TrxPx activity						bf	2014-06-18T11:03:26Z						biological_process											owl:Class	
GO:1902480	biolink:NamedThing	protein localization to mitotic spindle	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.	got7fsn_ti	protein localization in mitotic spindle|protein localisation to mitotic spindle|protein localisation in mitotic spindle						mah	2013-11-04T13:16:47Z						biological_process											owl:Class	
GO:0140077	biolink:NamedThing	positive regulation of lipoprotein transport	Any process that activates or increases the rate or extent of lipoprotein transport.	got7fsn_ti							pg	2017-07-21T15:41:54Z						biological_process											owl:Class	
GO:0045329	biolink:NamedThing	carnitine biosynthetic process	The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	got7fsn_ti	carnitine anabolism|vitamin Bt biosynthesis|carnitine synthesis|carnitine formation|carnitine biosynthesis|vitamin Bt biosynthetic process													biological_process											owl:Class	
GO:0044585	biolink:NamedThing	cellobiose binding	Binding to cellobiose, a disaccharide that represents the basic repeating unit of cellulose.	got7fsn_ti							jl	2012-04-24T04:55:10Z						molecular_function											owl:Class	
GO:1905286	biolink:NamedThing	serine-type peptidase complex	A protein complex which is capable of serine-type peptidase activity.	got7fsn_ti	Factor VII - TF complex				An example of this is F7 in human (P08709) in PMID:18640965 (inferred from direct assay).		bhm	2016-06-21T14:20:20Z						cellular_component											owl:Class	
GO:1905535	biolink:NamedThing	regulation of eukaryotic translation initiation factor 4F complex assembly	Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.	got7fsn_ti	regulation of eIF4F assembly|regulation of eIF-4F assembly						bc	2016-10-06T14:04:58Z						biological_process											owl:Class	
GO:0055066	biolink:NamedThing	obsolete di-, tri-valent inorganic cation homeostasis	OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations within an organism or cell.	got7fsn_ti	di-, tri-valent inorganic cation homeostasis				This term was made obsolete because it has been split.	GO:0072507|GO:0072508				True				biological_process											owl:Class	
GO:1901206	biolink:NamedThing	obsolete positive regulation of adrenergic receptor signaling pathway involved in heart process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.	got7fsn_ti	upregulation of beta-adrenergic receptor signalling pathway involved in heart process|positive regulation of adrenergic receptor signalling pathway involved in heart process|up regulation of adrenergic receptor signalling pathway involved in heart process|up regulation of beta-adrenergic receptor signalling pathway involved in heart process|up-regulation of beta-adrenergic receptor signalling pathway involved in heart process|up regulation of adrenergic receptor signaling pathway involved in heart process|activation of beta-adrenergic receptor signalling pathway involved in heart process|up-regulation of adrenergic receptor signalling pathway involved in heart process|activation of adrenergic receptor signalling pathway involved in heart process|positive regulation of beta-adrenergic receptor signalling pathway involved in heart process|activation of adrenergic receptor signaling pathway involved in heart process|upregulation of adrenergic receptor signalling pathway involved in heart process|upregulation of adrenergic receptor signaling pathway involved in heart process|up-regulation of adrenergic receptor signaling pathway involved in heart process	https://github.com/geneontology/go-ontology/issues/14733			This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		hjd	2012-07-30T18:33:22Z		True				biological_process											owl:Class	
GO:0042340	biolink:NamedThing	keratan sulfate catabolic process	The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.	got7fsn_ti	keratan sulphate catabolism|keratan sulphate catabolic process|keratan sulfate catabolism|keratan sulfate degradation|keratan sulfate breakdown													biological_process											owl:Class	
GO:1902425	biolink:NamedThing	positive regulation of attachment of mitotic spindle microtubules to kinetochore	Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.	got7fsn_ti	positive regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|positive regulation of attachment of spindle microtubules to mitotic chromosome|up-regulation of mitotic bipolar attachment|up-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|upregulation of attachment of spindle microtubules to kinetochore involved in mitosis|positive regulation of attachment of spindle microtubules to kinetochore during mitosis|up-regulation of attachment of spindle microtubules to kinetochore involved in mitosis|activation of attachment of spindle microtubules to kinetochore involved in mitosis|positive regulation of mitotic bipolar attachment|activation of attachment of spindle microtubules to mitotic chromosome|activation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|up regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|upregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|up-regulation of attachment of spindle microtubules to mitotic chromosome|activation of attachment of spindle microtubules to kinetochore during mitosis|up-regulation of attachment of spindle microtubules to kinetochore during mitosis|upregulation of attachment of spindle microtubules to kinetochore during mitosis|up regulation of attachment of spindle microtubules to mitotic chromosome|up regulation of attachment of spindle microtubules to kinetochore during mitosis|upregulation of mitotic bipolar attachment|positive regulation of attachment of spindle microtubules to kinetochore involved in mitosis|activation of mitotic bipolar attachment|up regulation of mitotic bipolar attachment|upregulation of attachment of spindle microtubules to mitotic chromosome|up regulation of attachment of spindle microtubules to kinetochore involved in mitosis						vw	2013-09-19T10:33:55Z						biological_process											owl:Class	
GO:1902191	biolink:NamedThing	2-methylbutanoyl-CoA(4-) biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-).	got7fsn_ti	2-methylbutanoyl-CoA(4-) biosynthesis|2-methylbutanoyl-CoA(4-) synthesis|2-methylbutanoyl-CoA(4-) anabolism|2-methylbutanoyl-CoA(4-) formation						ms	2013-06-06T09:40:25Z						biological_process											owl:Class	
GO:0007248	biolink:NamedThing	obsolete nuclear translocation of MAPK (mating sensu Saccharomyces)	OBSOLETE. Movement of a MAP kinase to the nucleus in the context of transduction of mating pheromone signal, as described for Saccharomyces.	got7fsn_ti	nuclear translocation of MAPK (mating sensu Saccharomyces)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:1904242	biolink:NamedThing	regulation of pancreatic trypsinogen secretion	Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion.	got7fsn_ti	regulation of pancreatic trypsinogen release						sl	2015-05-18T19:49:20Z						biological_process											owl:Class	
GO:0003931	biolink:NamedThing	obsolete Rho small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Any member of the Rho subfamily of the RAS superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.	got7fsn_ti	Rho small monomeric GTPase activity			GO:0003924	This term was made obsolete because it represents a gene product.	GO:0007010				True				molecular_function											owl:Class	
GO:0046360	biolink:NamedThing	2-oxobutyrate biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.	got7fsn_ti	alpha-ketobutyrate biosynthetic process|2-oxobutyrate synthesis|2-oxobutyrate formation|2-oxobutyrate anabolism|alpha-ketobutyrate biosynthesis|2-oxobutyrate biosynthesis													biological_process											owl:Class	
GO:1901353	biolink:NamedThing	positive regulation of phosphatidylglycerol biosynthetic process	Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process.	got7fsn_ti	positive regulation of phosphatidylglycerol synthesis|activation of phosphatidylglycerol anabolism|upregulation of phosphatidylglycerol formation|positive regulation of phosphatidylglycerol anabolism|activation of phosphatidylglycerol synthesis|upregulation of phosphatidylglycerol biosynthetic process|up-regulation of phosphatidylglycerol formation|up-regulation of phosphatidylglycerol biosynthetic process|positive regulation of phosphatidylglycerol formation|up regulation of phosphatidylglycerol formation|activation of phosphatidylglycerol biosynthetic process|up-regulation of phosphatidylglycerol anabolism|up regulation of phosphatidylglycerol biosynthesis|up regulation of phosphatidylglycerol anabolism|upregulation of phosphatidylglycerol anabolism|upregulation of phosphatidylglycerol biosynthesis|positive regulation of phosphatidylglycerol biosynthesis|activation of phosphatidylglycerol biosynthesis|up regulation of phosphatidylglycerol biosynthetic process|upregulation of phosphatidylglycerol synthesis|up-regulation of phosphatidylglycerol biosynthesis|up-regulation of phosphatidylglycerol synthesis|up regulation of phosphatidylglycerol synthesis|activation of phosphatidylglycerol formation						dgf	2012-09-12T20:48:11Z						biological_process											owl:Class	
GO:0072500	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor				This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand.	GO:0030522|GO:0030374|GO:0004879|GO:0000122	mah	2010-12-16T11:47:39Z		True				biological_process											owl:Class	
GO:1903390	biolink:NamedThing	positive regulation of synaptic vesicle uncoating	Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating.	got7fsn_ti	activation of synaptic vesicle coat protein depolymerization|positive regulation of synaptic vesicle coat depolymerization|positive regulation of synaptic vesicle coat protein depolymerization|activation of synaptic vesicle uncoating|upregulation of synaptic vesicle uncoating|up regulation of synaptic vesicle coat protein depolymerization|upregulation of synaptic vesicle coat protein depolymerization|upregulation of synaptic vesicle coat depolymerization|activation of synaptic vesicle coat depolymerization|up-regulation of synaptic vesicle uncoating|up-regulation of synaptic vesicle coat depolymerization|up regulation of synaptic vesicle coat depolymerization|up-regulation of synaptic vesicle coat protein depolymerization|up regulation of synaptic vesicle uncoating						pad	2014-08-27T10:03:10Z						biological_process											owl:Class	
GO:1903666	biolink:NamedThing	positive regulation of asexual reproduction	Any process that activates or increases the frequency, rate or extent of asexual reproduction.	got7fsn_ti	activation of asexual reproduction|up-regulation of asexual reproduction|upregulation of asexual reproduction|up regulation of asexual reproduction						pf	2014-11-26T21:13:40Z						biological_process											owl:Class	
GO:0046131	biolink:NamedThing	pyrimidine ribonucleoside metabolic process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	pyrimidine ribonucleoside metabolism													biological_process											owl:Class	
GO:0044444	biolink:NamedThing	obsolete cytoplasmic part	OBSOLETE. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	got7fsn_ti	cytoplasm component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005737				True				cellular_component											owl:Class	
GO:0045614	biolink:NamedThing	negative regulation of plasmatocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation.	got7fsn_ti	down regulation of plasmatocyte differentiation|downregulation of plasmatocyte differentiation|down-regulation of plasmatocyte differentiation|inhibition of plasmatocyte differentiation													biological_process											owl:Class	
GO:1900266	biolink:NamedThing	negative regulation of substance P receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding.	got7fsn_ti	down regulation of neurokinin-1 receptor binding|down regulation of substance P receptor ligand|downregulation of neurokinin-1 receptor binding|downregulation of substance P receptor ligand|down-regulation of neurokinin-1 receptor binding|down regulation of substance P receptor binding|inhibition of substance P receptor binding|negative regulation of substance P receptor ligand|down-regulation of substance P receptor binding|downregulation of substance P receptor binding|inhibition of neurokinin-1 receptor binding|down-regulation of substance P receptor ligand|inhibition of substance P receptor ligand|negative regulation of neurokinin-1 receptor binding						tb	2012-04-03T11:11:36Z						biological_process											owl:Class	
GO:0052320	biolink:NamedThing	positive regulation of phytoalexin metabolic process	Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.	got7fsn_ti	up-regulation of phytoalexin metabolism|activation of phytoalexin metabolism|positive regulation of phytoalexin metabolism|upregulation of phytoalexin metabolism|stimulation of phytoalexin metabolism|up regulation of phytoalexin metabolism													biological_process											owl:Class	
GO:1905059	biolink:NamedThing	P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	A calcium-transporting P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration.	got7fsn_ti	Ca2+-pumping ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of postsynaptic cytosolic calcium levels|plasma membrane Ca-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-translocating P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca(2+)-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium ABC transporter involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca2+-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium levels|calcium efflux ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|ATP phosphohydrolase (Ca2+-transporting) involved in regulation of postsynaptic cytosolic calcium ion concentration|sarco(endo)plasmic reticulum Ca2+-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|sarcoplasmic reticulum ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration						dos	2016-03-18T12:32:08Z						molecular_function											owl:Class	
GO:0005988	biolink:NamedThing	lactose metabolic process	The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose.	got7fsn_ti	lactose metabolism													biological_process											owl:Class	
GO:1901023	biolink:NamedThing	4-hydroxyphenylacetate catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate.	got7fsn_ti	4-hydroxyphenylacetate catabolism|4-hydroxyphenylacetate breakdown|4-hydroxyphenylacetate degradation						yaf	2012-06-18T02:31:58Z						biological_process											owl:Class	
GO:0106214	biolink:NamedThing	regulation of vesicle fusion with Golgi apparatus	Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.	got7fsn_ti							hjd	2019-06-27T15:12:22Z						biological_process											owl:Class	
GO:0016285	biolink:NamedThing	obsolete cytosol alanyl aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.	got7fsn_ti	cytosol aminopeptidase III activity|human liver aminopeptidase|arylamidase activity|aminopolypeptidase activity|liver aminopeptidase activity|puromycin-sensitive aminopeptidase activity|thiol-activated aminopeptidase activity|cytosol alanyl aminopeptidase activity|soluble alanyl aminopeptidase activity				This term was made obsolete because it represents a gene product and refers to cellular component information.	GO:0004177|GO:0008235				True		MetaCyc:3.4.11.14-RXN|EC:3.4.11.14		molecular_function											owl:Class	
GO:0046306	biolink:NamedThing	alkanesulfonate catabolic process	The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.	got7fsn_ti	alkanesulphonate catabolic process|alkanesulphonate catabolism|alkanesulfonate breakdown|alkanesulfonate catabolism|alkanesulfonate degradation													biological_process											owl:Class	
GO:0045889	biolink:NamedThing	obsolete positive regulation of transcription of homeotic gene (Polycomb group)	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the Polycomb group.	got7fsn_ti	positive regulation of transcription of homeotic gene (Polycomb group)				This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0045944				True				biological_process											owl:Class	
GO:0005733	biolink:NamedThing	obsolete small nucleolar RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	small nucleolar RNA|snoRNA				This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
GO:0018146	biolink:NamedThing	keratan sulfate biosynthetic process	The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.	got7fsn_ti	keratan sulfate formation|keratan sulfate synthesis|keratan sulfate biosynthesis|keratan sulfate anabolism|keratan sulphate biosynthetic process|keratan sulphate biosynthesis											RESID:AA0247		biological_process											owl:Class	
GO:0032204	biolink:NamedThing	regulation of telomere maintenance	Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0061470	biolink:NamedThing	T follicular helper cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.	got7fsn_ti	T-helper follicular cell differentiation						dph	2012-11-02T09:01:48Z						biological_process											owl:Class	
GO:0007273	biolink:NamedThing	obsolete regulation of synapse	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	regulation of synapse				This term was made obsolete because the term string made no sense.	GO:0007268				True				biological_process											owl:Class	
GO:1904262	biolink:NamedThing	negative regulation of TORC1 signaling	Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.	got7fsn_ti	down-regulation of TORC1 signaling|inhibition of TORC1 signaling|inhibition of TORC1 signal transduction|downregulation of TORC1 signaling|down regulation of TORC1 signaling|down-regulation of TORC1 signal transduction|down regulation of TORC1 signal transduction|negative regulation of TORC1 signal transduction|downregulation of TORC1 signal transduction						lb	2015-05-27T13:13:04Z						biological_process											owl:Class	
GO:1900713	biolink:NamedThing	regulation of violaceol I biosynthetic process	Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process.	got7fsn_ti	regulation of violaceol I anabolism|regulation of violaceol I biosynthesis|regulation of violaceol I formation|regulation of violaceol I synthesis						di	2012-05-22T05:04:12Z						biological_process											owl:Class	
GO:0016147	biolink:NamedThing	obsolete protein-synthesizing GTPase activity, elongation	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	protein-synthesizing GTPase activity, elongation				This term was made obsolete because it contains both process and function information.	GO:0003924|GO:0006414|GO:0003746|GO:0006412				True				molecular_function											owl:Class	
GO:1902823	biolink:NamedThing	negative regulation of late endosome to lysosome transport	Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport.	got7fsn_ti	down regulation of late endosome to lysosome transport|down-regulation of late endosome to lysosome transport|downregulation of late endosome to lysosome transport|inhibition of late endosome to lysosome transport						pad	2014-03-31T10:08:51Z						biological_process											owl:Class	
GO:0036418	biolink:NamedThing	intrinsic component of mycolate outer membrane	The component of the mycolate outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to MOM|intrinsic to mycolate outer membrane|intrinsic to mycomembrane						bf	2013-09-05T20:19:04Z						cellular_component											owl:Class	
GO:1902392	biolink:NamedThing	regulation of exodeoxyribonuclease activity	Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity.	got7fsn_ti							jl	2013-09-11T14:56:14Z						biological_process											owl:Class	
GO:0019157	biolink:NamedThing	obsolete malate oxidase activity	OBSOLETE. Catalysis of the reaction: (S)-malate + O(2) = H(2)O(2) + oxaloacetate.	got7fsn_ti	(S)-malate:oxygen oxidoreductase activity|malic oxidase activity|malic dehydrogenase II|FAD-dependent malate oxidase activity				This term is slated for obsoletion because RHEA indicates there is not enough experimental evidence.					True				molecular_function											owl:Class	
GO:1902984	biolink:NamedThing	pre-replicative complex assembly involved in premeiotic DNA replication	Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication.	got7fsn_ti	nuclear pre-replicative complex assembly involved in meiotic cell cycle|pre-replicative complex assembly involved in meiotic cell cycle DNA replication|pre-RC complex assembly involved in meiosis|pre-replicative complex formation involved in meiosis|pre-replicative complex assembly involved in meiosis						jl	2014-05-06T20:33:28Z						biological_process											owl:Class	
GO:0060167	biolink:NamedThing	regulation of adenosine receptor signaling pathway	Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.	got7fsn_ti	regulation of adenosine receptor signalling pathway													biological_process											owl:Class	
GO:0004253	biolink:NamedThing	obsolete gamma-renin activity	OBSOLETE. Catalysis of the cleavage of the Leu-Leu bond in synthetic tetradecapeptide renin substrate, producing angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes BZ-Arg-para-nitroanilide.	got7fsn_ti	gamma-renin activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
UBERON:0000101	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016305	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase activity, class II	OBSOLETE. A phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate; the human form can phosphorylate phosphatidylinositol-4,5-bisphosphate in the presence of phosphatidylserine.	got7fsn_ti	PI3KC2|phosphatidylinositol 3-kinase activity, class II				This term was made obsolete because it represents a class of gene products.	GO:0035005|GO:0016303|GO:0046934				True				molecular_function											owl:Class	
GO:2000397	biolink:NamedThing	positive regulation of ubiquitin-dependent endocytosis	Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis.	got7fsn_ti	positive regulation of ubiquitin-mediated endocytosis						mah	2011-02-22T11:25:42Z						biological_process											owl:Class	
GO:0000232	biolink:NamedThing	obsolete nuclear interphase chromosome	OBSOLETE. A chromosome found in the nucleus during interphase.	got7fsn_ti	nuclear interphase chromosome				This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000228				True				cellular_component											owl:Class	
GO:0000194	biolink:NamedThing	obsolete inactivation of MAPK (pseudohyphal growth)	OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.	got7fsn_ti	inactivation of MAPK (pseudohyphal growth)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0046479	biolink:NamedThing	glycosphingolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.	got7fsn_ti	glycosphingolipid catabolism|glycosphingolipid breakdown|glycosphingolipid degradation													biological_process											owl:Class	
GO:0019621	biolink:NamedThing	creatinine catabolic process to formate	The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.	got7fsn_ti	creatinine degradation to formate|creatinine breakdown to formate											MetaCyc:CRNFORCAT-PWY		biological_process											owl:Class	
GO:0043932	biolink:NamedThing	ossification involved in bone remodeling	The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.	got7fsn_ti	ossification involved in bone remodelling													biological_process											owl:Class	
GO:0085023	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VII secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:35:02Z		True				biological_process											owl:Class	
GO:0030394	biolink:NamedThing	fructoseglycine metabolic process	The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group.	got7fsn_ti	fructoseglycine metabolism													biological_process											owl:Class	
GO:0015447	biolink:NamedThing	obsolete type II protein secretor activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	type II protein secretor activity				This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True				molecular_function											owl:Class	
GO:1901982	biolink:NamedThing	maltose binding	Binding to maltose.	got7fsn_ti							tb	2013-03-13T18:17:19Z						molecular_function											owl:Class	
GO:1902009	biolink:NamedThing	positive regulation of toxin transport	Any process that activates or increases the frequency, rate or extent of toxin transport.	got7fsn_ti	upregulation of toxin transport|up-regulation of toxin transport|up regulation of toxin transport|activation of toxin transport						dph	2013-03-22T12:54:09Z						biological_process											owl:Class	
GO:0052346	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont nitric oxide production	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of defense-related symbiont NO production|positive regulation by organism of defense-related symbiont nitric oxide production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1900834	biolink:NamedThing	regulation of emericellin biosynthetic process	Any process that modulates the frequency, rate or extent of emericellin biosynthetic process.	got7fsn_ti	regulation of Variecoxanthone B formation|regulation of emericellin synthesis|regulation of emericellin formation|regulation of Variecoxanthone B anabolism|regulation of emericellin biosynthesis|regulation of Variecoxanthone B biosynthetic process|regulation of Variecoxanthone B biosynthesis|regulation of Variecoxanthone B synthesis|regulation of emericellin anabolism						di	2012-06-07T09:32:02Z						biological_process											owl:Class	
GO:0031525	biolink:NamedThing	menthol biosynthetic process	The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.	got7fsn_ti	menthol synthesis|menthol anabolism|menthol biosynthesis|menthol formation													biological_process											owl:Class	
GO:0042185	biolink:NamedThing	m-xylene catabolic process	The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	m-xylene catabolism|meta-xylene catabolism|m-xylene breakdown|m-xylene degradation|meta-xylene catabolic process											MetaCyc:PWY-142		biological_process											owl:Class	
GO:0046985	biolink:NamedThing	positive regulation of hemoglobin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	got7fsn_ti	activation of hemoglobin biosynthetic process|stimulation of hemoglobin biosynthetic process|positive regulation of hemoglobin formation|positive regulation of hemoglobin anabolism|up-regulation of hemoglobin biosynthetic process|positive regulation of haemoglobin biosynthetic process|positive regulation of haemoglobin biosynthesis|upregulation of hemoglobin biosynthetic process|positive regulation of hemoglobin biosynthesis|positive regulation of hemoglobin synthesis|up regulation of hemoglobin biosynthetic process													biological_process											owl:Class	
GO:0000414	biolink:NamedThing	regulation of histone H3-K36 methylation	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.	got7fsn_ti														biological_process											owl:Class	
GO:1903976	biolink:NamedThing	negative regulation of glial cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration.	got7fsn_ti	inhibition of glial cell migration|downregulation of glia cell migration|down-regulation of glial cell migration|down-regulation of glia cell migration|down regulation of glia cell migration|inhibition of glia cell migration|downregulation of glial cell migration|down regulation of glial cell migration|negative regulation of glia cell migration						nc	2015-03-02T15:13:38Z						biological_process											owl:Class	
GO:1902612	biolink:NamedThing	regulation of anti-Mullerian hormone signaling pathway	Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway.	got7fsn_ti							hjd	2014-01-09T15:39:30Z						biological_process											owl:Class	
GO:0032825	biolink:NamedThing	positive regulation of natural killer cell differentiation	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.	got7fsn_ti	up regulation of natural killer cell differentiation|activation of natural killer cell differentiation|stimulation of natural killer cell differentiation|positive regulation of natural killer cell development|upregulation of natural killer cell differentiation|up-regulation of natural killer cell differentiation|positive regulation of NK cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0015998	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006291	biolink:NamedThing	obsolete pyrimidine-dimer repair, DNA damage excision	OBSOLETE. The excision of damaged DNA during pyrimidine-dimer repair. A large multienzyme complex scans the DNA for a distortion in the double helix rather than for a specific base change. Once a bulky lesion is found, the phosphodiester backbone of the abnormal strand is cleaved on both sides of the distortion, and the portion of the strand containing the lesion (an oligonucleotide) is peeled away from the DNA double helix by a DNA helicase enzyme.	got7fsn_ti	pyrimidine-dimer repair, DNA damage excision				This term was made obsolete because this process can be subdivided into multiple processes.	GO:0006289				True				biological_process											owl:Class	
GO:0000047	biolink:NamedThing	obsolete Rieske iron-sulfur protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Rieske iron-sulphur protein|Rieske iron-sulfur protein				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0003302	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in heart jogging	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the process of heart jogging.	got7fsn_ti	transforming growth factor beta receptor signalling pathway involved in heart jogging						dph	2009-10-22T10:51:58Z						biological_process											owl:Class	
GO:1900867	biolink:NamedThing	sarcinapterin metabolic process	The chemical reactions and pathways involving sarcinapterin.	got7fsn_ti	sarcinapterin metabolism						tt	2012-06-12T04:34:10Z						biological_process											owl:Class	
UBERON:0003714	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018328	biolink:NamedThing	obsolete enzyme active site formation via 3'-phospho-L-histidine	OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:11168390.	GO:0008256				True		RESID:AA0036		biological_process											owl:Class	
GO:0008085	biolink:NamedThing	obsolete phototransduction, visible light, light adaptation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	phototransduction, visible light, light adaptation				This term was made obsolete because the term name is ambiguous.	GO:0007602				True				biological_process											owl:Class	
GO:0071877	biolink:NamedThing	regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway	Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.	got7fsn_ti	regulation of adrenergic receptor signalling pathway|regulation of adrenergic receptor signaling pathway						mah	2010-09-13T04:12:10Z						biological_process											owl:Class	
GO:0015814	biolink:NamedThing	p-aminobenzoyl-glutamate transport	The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0048122	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900537	biolink:NamedThing	obsolete negative regulation of glucose homeostasis	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose homeostasis.	got7fsn_ti	inhibition of glucose homeostasis|downregulation of glucose homeostasis|down regulation of glucose homeostasis|negative regulation of glucose homeostasis|down-regulation of glucose homeostasis				This term was obsoleted at the TermGenie Gatekeeper stage.		hjd	2012-05-10T06:53:14Z		True				biological_process											owl:Class	
GO:0033306	biolink:NamedThing	phytol metabolic process	The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.	got7fsn_ti	phytol metabolism													biological_process											owl:Class	
GO:2000997	biolink:NamedThing	regulation of cellulose catabolic process	Any process that modulates the frequency, rate or extent of cellulose catabolic process.	got7fsn_ti	regulation of cellulose degradation|regulation of cellulose breakdown|regulation of cellulose catabolism						tt	2011-08-08T03:21:20Z						biological_process											owl:Class	
GO:0035465	biolink:NamedThing	obsolete regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry	OBSOLETE. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of the lateral plate mesoderm with respect to its left and right halves.	got7fsn_ti	regulation of TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry			GO:1900175	This term was made obsolete because it describes regulation of the nodal signaling pathway. Nodal proteins are members of the TGF-beta superfamily, but are distinct from TGF-beta proteins themselves. TGF-beta proteins are not currently known to regulate left/right asymmetry in the lateral mesoderm.		bf	2010-04-19T01:36:23Z		True				biological_process											owl:Class	
GO:0003074	biolink:NamedThing	obsolete regulation of diuresis	OBSOLETE. Any process that modulates the rate of diuresis. Diuresis is the process of renal water excretion.	got7fsn_ti	regulation of diuresis				This term was made obsolete because its definition was inaccurate.	GO:0035809				True				biological_process											owl:Class	
GO:1905870	biolink:NamedThing	positive regulation of 3'-UTR-mediated mRNA stabilization	Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.	got7fsn_ti	up-regulation of 3'-untranslated region-mediated mRNA stabilization|up-regulation of 3'-UTR-mediated mRNA stabilization|activation of 3'-untranslated region-mediated mRNA stabilization|up regulation of 3'-UTR-mediated mRNA stabilization|up regulation of 3'-untranslated region-mediated mRNA stabilization|upregulation of 3'-untranslated region-mediated mRNA stabilization|upregulation of 3'-UTR-mediated mRNA stabilization|activation of 3'-UTR-mediated mRNA stabilization|positive regulation of 3'-untranslated region-mediated mRNA stabilization						rz	2017-01-27T11:51:55Z						biological_process											owl:Class	
GO:1900848	biolink:NamedThing	positive regulation of naphtho-gamma-pyrone biosynthetic process	Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.	got7fsn_ti	upregulation of naphtho-gamma-pyrone biosynthetic process|activation of naphtho-gamma-pyrone biosynthetic process|up regulation of naphtho-gamma-pyrone biosynthetic process|up-regulation of naphtho-gamma-pyrone biosynthetic process						di	2012-06-07T09:43:11Z						biological_process											owl:Class	
GO:1903918	biolink:NamedThing	regulation of actin filament severing	Any process that modulates the frequency, rate or extent of actin filament severing.	got7fsn_ti	regulation of actin filament severing activity|regulation of barbed-end actin capping/severing activity|regulation of F-actin severing						als	2015-02-10T11:01:21Z						biological_process											owl:Class	
GO:0060052	biolink:NamedThing	neurofilament cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.	got7fsn_ti	neurofilament cytoskeleton organisation|neurofilament cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:1903339	biolink:NamedThing	negative regulation of cell wall organization or biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.	got7fsn_ti	inhibition of cell wall organisation or biogenesis|downregulation of cell wall organization or biogenesis at cellular level|down-regulation of cell wall organization or biogenesis at cellular level|negative regulation of cell wall organization or biogenesis at cellular level|negative regulation of cellular cell wall organisation or biogenesis|down-regulation of cellular cell wall organization or biogenesis|negative regulation of cellular cell wall organization or biogenesis|down regulation of cell wall organisation or biogenesis|down-regulation of cellular cell wall organisation or biogenesis|downregulation of cell wall organisation or biogenesis|down-regulation of cell wall organization or biogenesis|inhibition of cell wall organization or biogenesis at cellular level|downregulation of cellular cell wall organisation or biogenesis|down regulation of cellular cell wall organisation or biogenesis|inhibition of cell wall organization or biogenesis|inhibition of cellular cell wall organization or biogenesis|inhibition of cellular cell wall organisation or biogenesis|negative regulation of cell wall organisation or biogenesis|down regulation of cell wall organization or biogenesis at cellular level|down regulation of cell wall organization or biogenesis|down regulation of cellular cell wall organization or biogenesis|downregulation of cell wall organization or biogenesis|downregulation of cellular cell wall organization or biogenesis|down-regulation of cell wall organisation or biogenesis						vw	2014-08-18T13:20:58Z						biological_process											owl:Class	
GO:1902083	biolink:NamedThing	negative regulation of peptidyl-cysteine S-nitrosylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.	got7fsn_ti	down-regulation of protein S-nitrosylation|downregulation of peptidyl-cysteine S-nitrosylation|downregulation of protein S-nitrosylation|downregulation of S-nitrosylation|negative regulation of protein S-nitrosylation|negative regulation of S-nitrosylation|inhibition of S-nitrosylation|down regulation of peptidyl-cysteine S-nitrosylation|down-regulation of S-nitrosylation|inhibition of protein S-nitrosylation|down regulation of protein S-nitrosylation|down-regulation of peptidyl-cysteine S-nitrosylation|down regulation of S-nitrosylation|inhibition of peptidyl-cysteine S-nitrosylation						rl	2013-04-24T16:49:34Z						biological_process											owl:Class	
GO:1903075	biolink:NamedThing	pyridoxine import across plasma membrane	The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	pyridoxine import into cell						mah	2014-05-29T15:04:14Z						biological_process											owl:Class	
GO:0000193	biolink:NamedThing	obsolete activation of MAPK (pseudohyphal growth)	OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.	got7fsn_ti	activation of MAPK (pseudohyphal growth)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
PR:000007556	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009180	biolink:NamedThing	purine ribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine ribonucleoside diphosphate anabolism|purine ribonucleoside diphosphate synthesis|purine ribonucleoside diphosphate biosynthesis|purine ribonucleoside diphosphate formation													biological_process											owl:Class	
GO:0045615	biolink:NamedThing	positive regulation of plasmatocyte differentiation	Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation.	got7fsn_ti	up-regulation of plasmatocyte differentiation|stimulation of plasmatocyte differentiation|upregulation of plasmatocyte differentiation|activation of plasmatocyte differentiation|up regulation of plasmatocyte differentiation													biological_process											owl:Class	
GO:0030574	biolink:NamedThing	collagen catabolic process	The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.	got7fsn_ti	collagen degradation|collagen catabolism|collagen breakdown													biological_process											owl:Class	
GO:0050947	biolink:NamedThing	negative regulation of early stripe melanocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation.	got7fsn_ti	down regulation of early stripe melanocyte differentiation|inhibition of early stripe melanocyte differentiation|down-regulation of early stripe melanocyte differentiation|negative regulation of early stripe melanophore differentiation|downregulation of early stripe melanocyte differentiation													biological_process											owl:Class	
GO:2000902	biolink:NamedThing	cellooligosaccharide metabolic process	The chemical reactions and pathways involving a cellooligosaccharide.	got7fsn_ti	cellooligosaccharide metabolism						jl	2011-07-28T03:21:46Z						biological_process											owl:Class	
GO:0046687	biolink:NamedThing	response to chromate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.	got7fsn_ti	chromate sensitivity/resistance													biological_process											owl:Class	
GO:1903781	biolink:NamedThing	positive regulation of cardiac conduction	Any process that activates or increases the frequency, rate or extent of cardiac conduction.	got7fsn_ti	upregulation of cardiac conduction|activation of cardiac conduction|up regulation of cardiac conduction|up-regulation of cardiac conduction						rph	2015-01-07T13:20:28Z						biological_process											owl:Class	
GO:0046055	biolink:NamedThing	dGMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).	got7fsn_ti	dGMP degradation|dGMP breakdown|dGMP catabolism													biological_process											owl:Class	
GO:1902291	biolink:NamedThing	cell cycle DNA replication DNA ligation	Any DNA ligation that is involved in cell cycle DNA replication.	got7fsn_ti	DNA ligation involved in cell cycle DNA replication						jl	2013-07-09T16:05:45Z						biological_process											owl:Class	
GO:1904544	biolink:NamedThing	positive regulation of free ubiquitin chain polymerization	Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization.	got7fsn_ti	up-regulation of free ubiquitin chain polymerization|activation of free ubiquitin chain polymerization|upregulation of free ubiquitin chain polymerization|up regulation of free ubiquitin chain polymerization				An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype).		pad	2015-08-11T11:45:06Z						biological_process											owl:Class	
GO:0048034	biolink:NamedThing	heme O biosynthetic process	The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.	got7fsn_ti	haem O biosynthetic process|heme O biosynthesis|heme O anabolism|heme O synthesis|haem O biosynthesis|heme O formation													biological_process											owl:Class	
GO:2000522	biolink:NamedThing	positive regulation of immunological synapse formation	Any process that activates or increases the frequency, rate or extent of immunological synapse formation.	got7fsn_ti	positive regulation of formation of immunological synapse						ebc	2011-03-23T10:18:23Z						biological_process											owl:Class	
GO:1901636	biolink:NamedThing	obsolete negative regulation of maintenance of presynaptic active zone structure	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of presynaptic active zone structure.	got7fsn_ti	down regulation of maintenance of presynaptic active zone structure|inhibition of maintenance of presynaptic active zone structure|down-regulation of maintenance of presynaptic active zone structure|negative regulation of maintenance of presynaptic active zone structure|downregulation of maintenance of presynaptic active zone structure				This term was obsoleted at the TermGenie Gatekeeper stage.		ans	2012-11-15T14:17:07Z		True				biological_process											owl:Class	
GO:0098703	biolink:NamedThing	calcium ion import across plasma membrane	The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	calcium ion import into cell|calcium ion uptake into cell						mah	2013-02-07T13:07:59Z			GO:1990035			biological_process											owl:Class	
GO:0010941	biolink:NamedThing	regulation of cell death	Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.	got7fsn_ti														biological_process											owl:Class	
GO:0072427	biolink:NamedThing	obsolete detection of DNA damage stimulus involved in intra-S DNA damage checkpoint	OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to an intra-S DNA damage checkpoint.	got7fsn_ti	intra-S DNA damage checkpoint sensor mechanism|intra-S DNA damage checkpoint sensor process|sensing involved in intra-S DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:30:27Z		True				biological_process											owl:Class	
GO:1901216	biolink:NamedThing	positive regulation of neuron death	Any process that activates or increases the frequency, rate or extent of neuron death.	got7fsn_ti	upregulation of neuron death|up-regulation of neuron death|positive regulation of neuronal cell death|up regulation of neuron death|upregulation of neuronal cell death|up-regulation of neuronal cell death|positive regulation of neuron cell death|upregulation of neuron cell death|up-regulation of neuron cell death|up regulation of neuronal cell death|activation of neuronal cell death|activation of neuron death|up regulation of neuron cell death|activation of neuron cell death						rph	2012-08-02T09:58:15Z						biological_process											owl:Class	
GO:1904332	biolink:NamedThing	negative regulation of error-prone translesion synthesis	Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis.	got7fsn_ti	inhibition of mutagenic postreplication DNA repair|inhibition of error-prone translesion synthesis|negative regulation of mutagenic postreplication DNA repair|inhibition of mutagenic PRR|down-regulation of mutagenic postreplication DNA repair|down regulation of mutagenic PRR|downregulation of mutagenic postreplication DNA repair|down-regulation of error-prone translesion synthesis|downregulation of mutagenic PRR|downregulation of error-prone postreplication DNA repair|negative regulation of mutagenic PRR|negative regulation of error-prone postreplication DNA repair|inhibition of error-prone postreplication DNA repair|down regulation of error-prone translesion synthesis|down-regulation of error-prone postreplication DNA repair|down regulation of mutagenic postreplication DNA repair|downregulation of error-prone translesion synthesis|down-regulation of mutagenic PRR|down regulation of error-prone postreplication DNA repair						kmv	2015-06-11T16:24:53Z						biological_process											owl:Class	
GO:0005627	biolink:NamedThing	obsolete ascus	OBSOLETE. A sac-like fruiting body (ascomycete Fungi); contains ascospores (typically eight in number).	got7fsn_ti	ascus				This term was made obsolete because it is a structure that contains cell (ascospores) rather than a cellular component. To update annotations, consider the external ontology term 'ascus ; FAO:0000014'.					True				cellular_component											owl:Class	
GO:0070349	biolink:NamedThing	positive regulation of brown fat cell proliferation	Any process that activates or increases the rate or extent of brown fat cell proliferation.	got7fsn_ti	up-regulation of brown fat cell proliferation|up regulation of brown fat cell proliferation|positive regulation of brown adipocyte proliferation|activation of brown fat cell proliferation|stimulation of brown fat cell proliferation|positive regulation of brown adipose cell proliferation|upregulation of brown fat cell proliferation													biological_process											owl:Class	
GO:0035830	biolink:NamedThing	palmatine metabolic process	The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants.	got7fsn_ti	palmatine metabolism						bf	2011-05-04T03:04:38Z						biological_process											owl:Class	
GO:1902749	biolink:NamedThing	regulation of cell cycle G2/M phase transition	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.	got7fsn_ti							jl	2014-03-05T15:38:15Z						biological_process											owl:Class	
CHEBI:24174	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000293	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903654	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter	Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter.	got7fsn_ti							vw	2014-11-25T11:00:43Z						biological_process											owl:Class	
GO:1902882	biolink:NamedThing	regulation of response to oxidative stress	Any process that modulates the frequency, rate or extent of response to oxidative stress.	got7fsn_ti							kmv	2014-04-03T20:29:52Z						biological_process											owl:Class	
GO:1903557	biolink:NamedThing	positive regulation of tumor necrosis factor superfamily cytokine production	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.	got7fsn_ti	up-regulation of tumor necrosis factor superfamily cytokine production|upregulation of TNFSF cytokine production|up regulation of TNFSF cytokine production|positive regulation of TNF superfamily production|activation of tumor necrosis factor superfamily cytokine production|up regulation of TNF superfamily production|activation of TNFSF cytokine production|upregulation of TNF superfamily production|up-regulation of TNF superfamily production|activation of TNF superfamily production|positive regulation of TNFSF cytokine production|upregulation of tumor necrosis factor superfamily cytokine production|up-regulation of TNFSF cytokine production|up regulation of tumor necrosis factor superfamily cytokine production						pga	2014-10-21T10:26:23Z						biological_process											owl:Class	
GO:2001034	biolink:NamedThing	positive regulation of double-strand break repair via nonhomologous end joining	Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	got7fsn_ti	positive regulation of NHEJ						yaf	2011-08-24T09:25:51Z						biological_process											owl:Class	
GO:1903409	biolink:NamedThing	reactive oxygen species biosynthetic process	The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen.	got7fsn_ti	ROS generation|ROS formation|reactive oxygen species anabolism|reactive oxygen species formation|reactive oxygen species generation|reactive oxygen species biosynthesis|reactive oxygen species synthesis						bf	2014-09-03T09:19:13Z						biological_process											owl:Class	
GO:0043859	biolink:NamedThing	obsolete cyanophycinase activity	OBSOLETE. Catalysis of the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.	got7fsn_ti	cyanophycinase activity			GO:0008236	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0015032	biolink:NamedThing	obsolete storage protein import into fat body	OBSOLETE. The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life.	got7fsn_ti	import of storage protein into fat body|storage protein import into fat body cells|storage protein uptake into fat body cells|storage protein transport into fat body cells|storage protein import by fat body cells|fat body metabolism|fat body storage protein uptake|fat body metabolic process	https://github.com/geneontology/go-ontology/issues/12935			The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using 'receptor-mediated endocytosis'.					True				biological_process											owl:Class	
GO:2000577	biolink:NamedThing	obsolete regulation of microtubule motor activity, minus-end-directed	OBSOLETE. Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.	got7fsn_ti	regulation of ATP-dependent microtubule motor activity, minus-end-directed|regulation of minus-end-directed kinesin ATPase activity|regulation of kinesin ATP phosphohydrolase (minus-end-directed)|regulation of minus-end-directed microtubule motor activity	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140659	bf	2011-04-05T08:37:52Z		True				biological_process											owl:Class	
GO:0090740	biolink:NamedThing	integral component of pigment granule membrane	The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti							tb	2017-05-16T17:48:35Z						cellular_component											owl:Class	
GO:1904647	biolink:NamedThing	response to rotenone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.	got7fsn_ti							sl	2015-08-31T20:55:32Z						biological_process											owl:Class	
GO:1900078	biolink:NamedThing	positive regulation of cellular response to insulin stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.	got7fsn_ti	upregulation of cellular response to insulin stimulus|up regulation of cellular response to insulin stimulus|activation of cellular response to insulin stimulus|up-regulation of cellular response to insulin stimulus						yaf	2012-01-31T11:24:30Z						biological_process											owl:Class	
GO:0010297	biolink:NamedThing	heteropolysaccharide binding	Binding to a heteropolysaccharide, a glycan composed of more than one type of monosaccharide residue.	got7fsn_ti	heteroglycan binding													molecular_function											owl:Class	
GO:0051821	biolink:NamedThing	obsolete dissemination or transmission of organism from other organism involved in symbiotic interaction	OBSOLETE. The movement of an organism from a second organism to another place in the environment, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism.	got7fsn_ti	dissemination or transmission of organism from other organism during symbiotic interaction				This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.					True				biological_process											owl:Class	
GO:0030807	biolink:NamedThing	obsolete positive regulation of cyclic nucleotide catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.	got7fsn_ti	upregulation of cyclic nucleotide catabolic process|up-regulation of cyclic nucleotide catabolic process|positive regulation of cyclic nucleotide breakdown|activation of cyclic nucleotide catabolic process|positive regulation of cyclic nucleotide degradation|stimulation of cyclic nucleotide catabolic process|up regulation of cyclic nucleotide catabolic process|positive regulation of cyclic nucleotide catabolism				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0003775	biolink:NamedThing	obsolete axonemal motor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	axonemal motor activity				This term was made obsolete because it includes cellular component information.	GO:0005930|GO:0003777				True				molecular_function											owl:Class	
GO:1900716	biolink:NamedThing	regulation of violaceol II biosynthetic process	Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process.	got7fsn_ti	regulation of violaceol II synthesis|regulation of violaceol II anabolism|regulation of violaceol II biosynthesis|regulation of violaceol II formation						di	2012-05-22T05:05:37Z						biological_process											owl:Class	
GO:1905031	biolink:NamedThing	regulation of membrane repolarization during cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.	got7fsn_ti							rph	2016-03-07T10:24:34Z						biological_process											owl:Class	
GO:0033228	biolink:NamedThing	cysteine export across plasma membrane	The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	cysteine export													biological_process											owl:Class	
GO:1901562	biolink:NamedThing	response to paraquat	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.	got7fsn_ti							mah	2012-11-02T15:32:41Z						biological_process											owl:Class	
GO:0004206	biolink:NamedThing	obsolete caspase-10 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	caspase-10 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1901580	biolink:NamedThing	regulation of telomeric RNA transcription from RNA pol II promoter	Any process that modulates the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.	got7fsn_ti	regulation of telomeric RNA transcription from Pol II promoter						al	2012-11-06T11:07:16Z						biological_process											owl:Class	
GO:0062137	biolink:NamedThing	cargo receptor complex	Any protein complex that is part of a membrane and which functions as a cargo receptor.	got7fsn_ti							dph	2019-07-08T18:09:01Z						cellular_component											owl:Class	
GO:1900155	biolink:NamedThing	negative regulation of bone trabecula formation	Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation.	got7fsn_ti	down-regulation of bone trabeculation|negative regulation of bone trabecula biogenesis|down-regulation of bone trabecula biogenesis|inhibition of bone trabeculation|negative regulation of skeletal trabecula biogenesis|down regulation of bone trabecula biogenesis|downregulation of skeletal trabecula formation|negative regulation of skeletal trabecula formation|down regulation of bone trabeculation|down-regulation of skeletal trabecula biogenesis|downregulation of skeletal trabecula biogenesis|down-regulation of skeletal trabeculation|inhibition of bone trabecula biogenesis|downregulation of bone trabecula biogenesis|down-regulation of skeletal trabecula formation|down regulation of skeletal trabecula formation|negative regulation of skeletal trabeculation|inhibition of skeletal trabecula formation|inhibition of skeletal trabecula biogenesis|down regulation of bone trabecula formation|negative regulation of bone trabeculation|down-regulation of bone trabecula formation|down regulation of skeletal trabecula biogenesis|downregulation of bone trabeculation|down regulation of skeletal trabeculation|downregulation of bone trabecula formation|downregulation of skeletal trabeculation|inhibition of skeletal trabeculation|inhibition of bone trabecula formation						vk	2012-03-07T01:47:07Z						biological_process											owl:Class	
GO:0070107	biolink:NamedThing	regulation of interleukin-27-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27-mediated binding to a cell surface receptor.	got7fsn_ti	regulation of interleukin-27-mediated signalling pathway|regulation of IL27RA/IL6ST signaling pathway|regulation of IL-27-mediated signaling pathway													biological_process											owl:Class	
GO:0000733	biolink:NamedThing	obsolete DNA strand renaturation	OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14671			This term was obsoleted because it represents a molecular function.	GO:0036310				True				biological_process											owl:Class	
GO:0048037	biolink:NamedThing	obsolete cofactor binding	OBSOLETE. Binding to a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.	got7fsn_ti					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group binding interactions that are not all chemically related by the fact that they may be used as a cofactor.					True				molecular_function											owl:Class	
GO:0034143	biolink:NamedThing	regulation of toll-like receptor 4 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.	got7fsn_ti	regulation of TLR4 signaling pathway|regulation of toll-like receptor 4 signalling pathway													biological_process											owl:Class	
GO:0043517	biolink:NamedThing	positive regulation of DNA damage response, signal transduction by p53 class mediator	Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.	got7fsn_ti	activation of DNA damage response, signal transduction by p53 class mediator|upregulation of DNA damage response, signal transduction by p53 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator|up regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of p53 induced by DNA damage response|stimulation of DNA damage response, signal transduction by p53 class mediator													biological_process											owl:Class	
GO:0016921	biolink:NamedThing	obsolete pyroglutamyl-peptidase II activity	OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.	got7fsn_ti	TRH-specific aminopeptidase activity|pyroglutamyl aminopeptidase II activity|thyrotropin-releasing hormone degrading ectoenzyme activity|thyroliberinase activity|thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity|pyroglutamyl-peptidase II activity|thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity|PAP-II activity|thyrotropin-releasing hormone-degrading peptidase activity|TRH-degrading ectoenzyme activity|pyroglutamyl peptidase II|thyrotropin-releasing factor pyroglutamate aminopeptidase activity|pyroglutamate aminopeptidase II|TRH-DE activity				This term was made obsolete because it represents a gene product.	GO:0008237|GO:0016920				True		MetaCyc:3.4.19.6-RXN|EC:3.4.19.6		molecular_function											owl:Class	
GO:0052058	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via substance secreted by type IV secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type IV secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0046445	biolink:NamedThing	benzyl isoquinoline alkaloid metabolic process	The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.	got7fsn_ti	benzyl isoquinoline alkaloid metabolism													biological_process											owl:Class	
GO:0033472	biolink:NamedThing	GDP-L-galactose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-L-galactose formation|GDP-L-galactose biosynthesis|GDP-L-galactose anabolism|GDP-L-galactose synthesis											MetaCyc:PWY-5115		biological_process											owl:Class	
GO:0052138	biolink:NamedThing	obsolete aerotaxis on or near host	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0019019	biolink:NamedThing	obsolete tripartite viral genome	OBSOLETE. A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:0046904	biolink:NamedThing	calcium oxalate binding	Binding to calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi.	got7fsn_ti														molecular_function											owl:Class	
UBERON:2000425	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045648	biolink:NamedThing	positive regulation of erythrocyte differentiation	Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.	got7fsn_ti	positive regulation of red blood cell differentiation|activation of erythrocyte differentiation|upregulation of erythrocyte differentiation|up-regulation of erythrocyte differentiation|positive regulation of RBC differentiation|stimulation of erythrocyte differentiation|up regulation of erythrocyte differentiation													biological_process											owl:Class	
GO:0045679	biolink:NamedThing	regulation of R8 cell differentiation	Any process that modulates the frequency, rate or extent of R8 differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0000990	biolink:NamedThing	obsolete transcription factor activity, core RNA polymerase binding	OBSOLETE. Binding to an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	core RNA polymerase binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0043175|GO:0140110	krc	2010-08-10T05:01:03Z		True				molecular_function											owl:Class	
GO:0046081	biolink:NamedThing	dUTP catabolic process	The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.	got7fsn_ti	dUTP breakdown|dUTP degradation|dUTP catabolism													biological_process											owl:Class	
GO:0031652	biolink:NamedThing	positive regulation of heat generation	Any process that activates or increases the rate or extent of heat generation.	got7fsn_ti	up regulation of heat generation|activation of heat generation|stimulation of heat generation|up-regulation of heat generation|upregulation of heat generation													biological_process											owl:Class	
GO:0052100	biolink:NamedThing	obsolete intraspecies quorum sensing	OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules.	got7fsn_ti					The reason for obsoletion is that this term was an unnecessary grouping term.					True				biological_process											owl:Class	
GO:1901616	biolink:NamedThing	organic hydroxy compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound.	got7fsn_ti	organic hydroxy compound breakdown|organic hydroxy compound catabolism|organic hydroxy compound degradation						pr	2012-11-13T12:54:31Z						biological_process											owl:Class	
GO:1905631	biolink:NamedThing	cellular response to glyceraldehyde	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.	got7fsn_ti							sl	2016-10-31T16:32:27Z						biological_process											owl:Class	
GO:1901847	biolink:NamedThing	nicotinate metabolic process	The chemical reactions and pathways involving nicotinate.	got7fsn_ti	nicotinate metabolism						yaf	2013-01-28T11:23:48Z						biological_process											owl:Class	
GO:0032228	biolink:NamedThing	regulation of synaptic transmission, GABAergic	Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).	got7fsn_ti														biological_process											owl:Class	
GO:0017088	biolink:NamedThing	obsolete X-Pro dipeptidyl-peptidase activity	OBSOLETE. Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile.	got7fsn_ti	X-Pro dipeptidyl-peptidase activity|X-prolyl dipeptidyl peptidase activity|Xaa-Pro dipeptidyl-peptidase activity|PepX|X-prolyl dipeptidyl aminopeptidase activity			GO:0008239	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
UBERON:0004141	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904490	biolink:NamedThing	negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of mitochondrial unfolded protein response.	got7fsn_ti	negative regulation of mtUPR by down regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by down-regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by downregulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by downregulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by inhibition of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by down regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from Pol II promoter|negative regulation of mitochondrial unfolded protein response by down-regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of mtUPR by inhibition of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by inhibition of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by downregulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down-regulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter, global|negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of global transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of global transcription from Pol II promoter|negative regulation of mtUPR by down-regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by inhibition of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by downregulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter, global|negative regulation of mtUPR by negative regulation of transcription from Pol II promoter						kmv	2015-07-17T18:15:13Z						biological_process											owl:Class	
GO:1905517	biolink:NamedThing	macrophage migration	The orderly movement of a macrophage from one site to another.	got7fsn_ti							sl	2016-09-30T22:17:45Z						biological_process											owl:Class	
GO:1905779	biolink:NamedThing	positive regulation of exonuclease activity	Any process that activates or increases the frequency, rate or extent of exonuclease activity.	got7fsn_ti	positive regulation of exonuclease IX activity|upregulation of exonuclease IX activity|up-regulation of exonuclease IX activity|up-regulation of exonuclease activity|activation of exonuclease IX activity|activation of exonuclease activity|up regulation of exonuclease activity|upregulation of exonuclease activity|up regulation of exonuclease IX activity						nc	2016-12-21T21:32:24Z						biological_process											owl:Class	
CHEBI:15705	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902711	biolink:NamedThing	GABA-A receptor complex	A protein complex which is capable of GABA-A receptor activity. In human, it is usually composed of either two alpha, two beta and one gamma chain of the GABA-A receptor subunits or 5 chains of the GABA-A receptor subunits rho1-3 (formally known as GABA-C receptor).	got7fsn_ti					An example of this is GBRA1 in human (UniProt symbol P14867) in PMID:18790874.		bhm	2014-02-21T09:19:58Z						cellular_component											owl:Class	
GO:0002703	biolink:NamedThing	regulation of leukocyte mediated immunity	Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.	got7fsn_ti	regulation of leucocyte mediated immunity|regulation of immune cell mediated immunity													biological_process											owl:Class	
GO:0042632	biolink:NamedThing	cholesterol homeostasis	Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.	got7fsn_ti	positive regulation of cholesterol homeostasis|regulation of cholesterol homeostasis										GO:2000189|GO:2000188			biological_process											owl:Class	
GO:0099103	biolink:NamedThing	channel activator activity	Direct interaction with a channel (binding or modification), resulting in its opening. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.	got7fsn_ti	channel gating activity													molecular_function											owl:Class	
CHEBI:203600	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0086007	biolink:NamedThing	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti							tb	2011-11-10T08:04:42Z						molecular_function											owl:Class	
GO:1900633	biolink:NamedThing	pentadecane metabolic process	The chemical reactions and pathways involving pentadecane.	got7fsn_ti	pentadecane metabolism						tt	2012-05-21T06:51:34Z						biological_process											owl:Class	
GO:0061926	biolink:NamedThing	positive regulation of formation of radial glial scaffolds	Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds.	got7fsn_ti	positive regulation of Bergmann fiber formation|positive regulation of radial glial scaffold formation|positive regulation of Bergmann fiber biosynthesis						dph	2017-08-02T16:29:37Z						biological_process											owl:Class	
GO:0046110	biolink:NamedThing	xanthine metabolic process	The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.	got7fsn_ti	xanthine metabolism													biological_process											owl:Class	
UBERON:0005083	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070905	biolink:NamedThing	serine binding	Binding to 2-amino-3-hydroxypropanoic acid.	got7fsn_ti	Ser binding						mah	2009-09-04T03:28:29Z						molecular_function											owl:Class	
GO:0002884	biolink:NamedThing	negative regulation of hypersensitivity	Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.	got7fsn_ti	downregulation of hypersensitivity|down-regulation of hypersensitivity|down regulation of hypersensitivity|inhibition of hypersensitivity													biological_process											owl:Class	
GO:1902140	biolink:NamedThing	response to inositol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.	got7fsn_ti							al	2013-05-21T13:42:10Z						biological_process											owl:Class	
GO:0046000	biolink:NamedThing	positive regulation of ecdysteroid secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.	got7fsn_ti	stimulation of ecdysteroid secretion|activation of ecdysteroid secretion|upregulation of ecdysteroid secretion|up regulation of ecdysteroid secretion|up-regulation of ecdysteroid secretion													biological_process											owl:Class	
GO:1902650	biolink:NamedThing	negative regulation of histone H2A-H2B dimer displacement	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A-H2B dimer displacement.	got7fsn_ti	inhibition of histone H2A-H2B dimer displacement|down-regulation of histone H2A-H2B dimer displacement|downregulation of histone H2A-H2B dimer displacement|down regulation of histone H2A-H2B dimer displacement						di	2014-01-21T18:19:14Z						biological_process											owl:Class	
GO:0009245	biolink:NamedThing	lipid A biosynthetic process	The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.	got7fsn_ti	lipid A biosynthesis|lipid A anabolism|lipid A synthesis|lipid A formation											MetaCyc:NAGLIPASYN-PWY		biological_process											owl:Class	
GO:0045923	biolink:NamedThing	positive regulation of fatty acid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.	got7fsn_ti	positive regulation of fatty acid metabolism|upregulation of fatty acid metabolic process|up-regulation of fatty acid metabolic process|up regulation of fatty acid metabolic process|activation of fatty acid metabolic process|stimulation of fatty acid metabolic process													biological_process											owl:Class	
GO:0090236	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in somitogenesis	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0001756|GO:0006357	tb	2010-01-20T11:12:29Z		True				biological_process											owl:Class	
GO:0052389	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052047	biolink:NamedThing	obsolete symbiotic process mediated by secreted substance	OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	interaction with other organism via secreted substance during symbiotic interaction|interaction with other organism via secreted substance involved in symbiotic interaction				This term was obsoleted because it has been misused to annotate host proteins.					True				biological_process											owl:Class	
GO:0090431	biolink:NamedThing	alkyl caffeate ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate.	got7fsn_ti	alkyl caffeate ester biosynthesis|alkyl caffeate ester formation|alkyl caffeate ester synthesis|alkyl caffeate ester anabolism						tb	2012-07-25T11:12:09Z						biological_process											owl:Class	
GO:1900664	biolink:NamedThing	regulation of emodin biosynthetic process	Any process that modulates the frequency, rate or extent of emodin biosynthetic process.	got7fsn_ti	regulation of emodin synthesis|regulation of emodin formation|regulation of emodin anabolism|regulation of emodin biosynthesis						di	2012-05-22T04:14:36Z						biological_process											owl:Class	
GO:1903327	biolink:NamedThing	negative regulation of tRNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.	got7fsn_ti	down regulation of tRNA metabolic process|downregulation of tRNA metabolism|down regulation of tRNA metabolism|negative regulation of tRNA metabolism|inhibition of tRNA metabolic process|down-regulation of tRNA metabolism|downregulation of tRNA metabolic process|inhibition of tRNA metabolism|down-regulation of tRNA metabolic process						vw	2014-08-18T13:08:58Z						biological_process											owl:Class	
GO:1901154	biolink:NamedThing	paromomycin catabolic process	The chemical reactions and pathways resulting in the breakdown of paromomycin.	got7fsn_ti	paromomycin breakdown|paromomycin degradation|paromomycin catabolism						yaf	2012-07-17T04:27:44Z						biological_process											owl:Class	
GO:0099014	biolink:NamedThing	neuronal dense core vesicle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.	got7fsn_ti														biological_process											owl:Class	
GO:1903629	biolink:NamedThing	positive regulation of dUTP diphosphatase activity	Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity.	got7fsn_ti	up regulation of dUTP pyrophosphatase activity|upregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|up regulation of deoxyuridine-triphosphatase activity|up regulation of dUTPase activity|up-regulation of desoxyuridine 5'-triphosphatase activity|activation of dUTP nucleotidohydrolase activity|upregulation of dUTP nucleotidohydrolase activity|up-regulation of dUTP diphosphatase activity|positive regulation of dUTP pyrophosphatase activity|up-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|activation of desoxyuridine 5'-triphosphatase activity|up-regulation of dUTP nucleotidohydrolase activity|up-regulation of dUTP pyrophosphatase activity|up regulation of dUTP nucleotidohydrolase activity|activation of dUTP diphosphatase activity|upregulation of dUTP pyrophosphatase activity|activation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|positive regulation of dUTP nucleotidohydrolase activity|upregulation of dUTP diphosphatase activity|activation of dUTPase activity|up regulation of desoxyuridine 5'-triphosphatase activity|activation of dUTP pyrophosphatase activity|upregulation of deoxyuridine-triphosphatase activity|positive regulation of dUTPase activity|up regulation of dUTP diphosphatase activity|up regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|positive regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|upregulation of desoxyuridine 5'-triphosphatase activity|activation of deoxyuridine-triphosphatase activity|upregulation of dUTPase activity|up-regulation of deoxyuridine-triphosphatase activity|up-regulation of dUTPase activity|positive regulation of desoxyuridine 5'-triphosphatase activity|positive regulation of deoxyuridine-triphosphatase activity						sl	2014-11-20T00:00:56Z						biological_process											owl:Class	
GO:0032960	biolink:NamedThing	regulation of inositol trisphosphate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.	got7fsn_ti	regulation of inositol trisphosphate formation|regulation of IP3 biosynthetic process|regulation of inositol trisphosphate biosynthesis|regulation of inositol trisphosphate anabolism|regulation of inositol trisphosphate synthesis|regulation of IP3 biosynthesis|regulation of myo-inositol trisphosphate biosynthetic process|regulation of myo-inositol trisphosphate biosynthesis													biological_process											owl:Class	
GO:0015687	biolink:NamedThing	ferric-hydroxamate import into cell	A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors.	got7fsn_ti	ferric-hydroxamate transport													biological_process											owl:Class	
GO:0062059	biolink:NamedThing	FACT complex binding	Binding to a FACT complex.	got7fsn_ti							dph	2018-08-31T13:49:30Z						molecular_function											owl:Class	
GO:0051516	biolink:NamedThing	regulation of bipolar cell growth	Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0032995	biolink:NamedThing	regulation of fungal-type cell wall biogenesis	Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin.	got7fsn_ti	regulation of chitin- and beta-glucan-containing cell wall biogenesis													biological_process											owl:Class	
GO:0046090	biolink:NamedThing	deoxyadenosine metabolic process	The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.	got7fsn_ti	deoxyadenosine metabolism													biological_process											owl:Class	
GO:2000957	biolink:NamedThing	regulation of cyclodextrin catabolic process	Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process.	got7fsn_ti	regulation of cyclodextrin catabolism						tt	2011-08-01T02:23:55Z						biological_process											owl:Class	
GO:0099075	biolink:NamedThing	mitochondrion-derived vesicle mediated transport	Transport from the mitochondrion, mediated by mitochondrion derived vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:2000179	biolink:NamedThing	positive regulation of neural precursor cell proliferation	Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.	got7fsn_ti							dph	2010-10-13T12:40:45Z						biological_process											owl:Class	
GO:0046074	biolink:NamedThing	dTMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate.	got7fsn_ti	dTMP catabolism|dTMP degradation|dTMP breakdown													biological_process											owl:Class	
GO:0110030	biolink:NamedThing	regulation of G2/MI transition of meiotic cell cycle	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.	got7fsn_ti							kmv	2017-07-12T19:02:19Z						biological_process											owl:Class	
GO:1903435	biolink:NamedThing	positive regulation of constitutive secretory pathway	Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway.	got7fsn_ti	activation of constitutive secretory pathway|up-regulation of constitutive secretory pathway|upregulation of constitutive secretory pathway|up regulation of constitutive secretory pathway						als	2014-09-15T15:07:48Z						biological_process											owl:Class	
GO:0030810	biolink:NamedThing	positive regulation of nucleotide biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.	got7fsn_ti	activation of nucleotide biosynthetic process|up regulation of nucleotide biosynthetic process|positive regulation of nucleotide formation|upregulation of nucleotide biosynthetic process|positive regulation of nucleotide biosynthesis|positive regulation of nucleotide synthesis|up-regulation of nucleotide biosynthetic process|stimulation of nucleotide biosynthetic process|positive regulation of nucleotide anabolism													biological_process											owl:Class	
GO:1902611	biolink:NamedThing	cellular response to N-phenylthiourea	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.	got7fsn_ti							rjd	2014-01-08T01:57:58Z						biological_process											owl:Class	
GO:0015468	biolink:NamedThing	obsolete colicin	OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it.	got7fsn_ti	colicin				This term was made obsolete because it represents a class of gene products.	GO:0019835|GO:0090729|GO:0005198|GO:0046930|GO:0046931|GO:0005102				True				molecular_function											owl:Class	
GO:1904063	biolink:NamedThing	negative regulation of cation transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport.	got7fsn_ti	inhibition of cation transmembrane transport|down regulation of cation transmembrane transport|down-regulation of cation transmembrane transport|downregulation of cation transmembrane transport						sl	2015-03-18T21:11:50Z						biological_process											owl:Class	
GO:0048294	biolink:NamedThing	negative regulation of isotype switching to IgE isotypes	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.	got7fsn_ti	negative regulation of isotype switch recombination to IgE isotypes|downregulation of isotype switching to IgE isotypes|down regulation of isotype switching to IgE isotypes|down-regulation of isotype switching to IgE isotypes|negative regulation of class switch recombination to IgE isotypes|negative regulation of class switching to IgE isotypes|inhibition of isotype switching to IgE isotypes													biological_process											owl:Class	
GO:2000806	biolink:NamedThing	positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.	got7fsn_ti	positive regulation of transcription termination from Pol II promoter, poly(A) coupled|positive regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|positive regulation of termination of RNA polymerase II transcription, polyadenylation-coupled						pr	2011-07-04T08:41:39Z						biological_process											owl:Class	
GO:1905666	biolink:NamedThing	regulation of protein localization to endosome	Any process that modulates the frequency, rate or extent of protein localization to endosome.	got7fsn_ti	regulation of protein localization in endosome|regulation of protein localisation in endosome						bc	2016-11-11T11:19:01Z						biological_process											owl:Class	
GO:0075088	biolink:NamedThing	obsolete positive regulation by host of symbiont G protein-coupled receptor signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by host of symbiont G-protein coupled receptor protein signal transduction				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0071512	biolink:NamedThing	obsolete MAPK import into nucleus involved in conjugation with cellular fusion	OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of conjugation with cellular fusion.	got7fsn_ti	nuclear translocation of MAPK involved in mating response|conjugation with cellular fusion, nuclear translocation of MAPK|conjugation with cellular fusion, MAPK import into nucleus|MAPK import into nucleus involved in mating response|nuclear translocation of MAPK involved in conjugation with cellular fusion				The reason for obsoletion is that this term represents a GO-CAM model.	GO:0006606	mah	2010-01-05T02:11:08Z		True				biological_process											owl:Class	
GO:0052122	biolink:NamedThing	obsolete negative aerotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative aerotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1905782	biolink:NamedThing	positive regulation of phosphatidylserine exposure on apoptotic cell surface	Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.	got7fsn_ti	activation of externalization of phosphatidylserine|up regulation of phosphatidylserine exposure on apoptotic cell surface|activation of phosphatidylserine exposure on apoptotic cell surface|up regulation of externalization of phosphatidylserine|positive regulation of externalization of phosphatidylserine|upregulation of phosphatidylserine exposure on apoptotic cell surface|up-regulation of phosphatidylserine exposure on apoptotic cell surface|up-regulation of externalization of phosphatidylserine|upregulation of externalization of phosphatidylserine						kmv	2017-01-04T15:19:22Z						biological_process											owl:Class	
GO:0070629	biolink:NamedThing	(1->4)-alpha-glucan metabolic process	The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.	got7fsn_ti	1,4-alpha-glucan metabolism|alpha-1,4 glucan metabolic process|1,4-alpha-D-glucan metabolism|(1->4)-alpha-D-glucan metabolism|alpha-1,4 glucan metabolism						mah	2009-05-01T04:45:42Z						biological_process											owl:Class	
GO:0002272	biolink:NamedThing	plasmacytoid dendritic cell differentiation involved in immune response	The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response.	got7fsn_ti	plasmacytoid dendritic cell differentiation during immune response													biological_process											owl:Class	
GO:1904065	biolink:NamedThing	G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission	Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission.	got7fsn_ti	acetylcholine receptor signalling, muscarinic pathway involved in upregulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission|G-protein coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission|muscarinic acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in stimulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in up regulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in positive regulation of acetylcholine secretion, neurotransmission|G-protein coupled acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in activation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in up-regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion						kmv	2015-03-19T15:28:47Z						biological_process											owl:Class	
GO:0070172	biolink:NamedThing	positive regulation of tooth mineralization	Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.	got7fsn_ti														biological_process											owl:Class	
GO:0045712	biolink:NamedThing	positive regulation of larval salivary gland boundary specification	Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism.	got7fsn_ti	stimulation of larval salivary gland determination|up regulation of larval salivary gland determination|activation of larval salivary gland determination|positive regulation of larval salivary gland determination|up-regulation of larval salivary gland determination|upregulation of larval salivary gland determination													biological_process											owl:Class	
GO:0015537	biolink:NamedThing	xanthosine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in).	got7fsn_ti	xanthosine permease activity|xanthosine:hydrogen ion symporter activity													molecular_function											owl:Class	
CHEBI:28053	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033262	biolink:NamedThing	regulation of nuclear cell cycle DNA replication	Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.	got7fsn_ti	regulation of DNA replication during S phase|regulation of DNA replication involved in S phase|regulation of DNA replication involved in S-phase													biological_process											owl:Class	
GO:0070667	biolink:NamedThing	negative regulation of mast cell proliferation	Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.	got7fsn_ti	down-regulation of mast cell proliferation|inhibition of mast cell proliferation|down regulation of mast cell proliferation|downregulation of mast cell proliferation						mah	2009-05-28T05:45:11Z						biological_process											owl:Class	
GO:0060251	biolink:NamedThing	regulation of glial cell proliferation	Any process that modulates the frequency, rate or extent of glial cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0016026	biolink:NamedThing	obsolete proteasome endopeptidase core	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	proteasome endopeptidase core				This term was made obsolete because it does not represent a molecular function.	GO:0004175				True				molecular_function											owl:Class	
GO:1900860	biolink:NamedThing	positive regulation of brevianamide F biosynthetic process	Any process that activates or increases the frequency, rate or extent of brevianamide F biosynthetic process.	got7fsn_ti	upregulation of brevianamide F biosynthetic process|up regulation of brevianamide F biosynthetic process|up-regulation of brevianamide F biosynthetic process						di	2012-06-07T09:53:25Z						biological_process											owl:Class	
GO:0006772	biolink:NamedThing	thiamine metabolic process	The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.	got7fsn_ti	thiamin metabolism|vitamin B1 metabolism|thiamine metabolism|thiamin metabolic process|vitamin B1 metabolic process											Wikipedia:Thiamine		biological_process											owl:Class	
GO:1901592	biolink:NamedThing	negative regulation of double-strand break repair via break-induced replication	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication.	got7fsn_ti	down-regulation of double-strand break repair via break-induced replication|inhibition of double-strand break repair via break-induced replication|down regulation of double-strand break repair via break-induced replication|downregulation of double-strand break repair via break-induced replication						al	2012-11-07T16:37:39Z						biological_process											owl:Class	
GO:0007244	biolink:NamedThing	obsolete MAPKKK cascade (mating sensu Saccharomyces)	OBSOLETE. MAPKKK cascade involved in transduction of mating pheromone signal, as described in Saccharomyces.	got7fsn_ti	MAPKKK cascade (mating sensu Saccharomyces)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:1905529	biolink:NamedThing	regulation of uracil import across plasma membrane	Any process that modulates the frequency, rate or extent of uracil import across plasma membrane.	got7fsn_ti							vw	2016-10-05T21:03:40Z						biological_process											owl:Class	
GO:0010754	biolink:NamedThing	negative regulation of cGMP-mediated signaling	Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.	got7fsn_ti	negative regulation of cGMP-mediated signalling													biological_process											owl:Class	
GO:0000188	biolink:NamedThing	obsolete inactivation of MAPK activity	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase.	got7fsn_ti	inactivation of MAPK during sporulation|termination of MAPK activity	https://github.com/geneontology/go-ontology/issues/21308			This term was obsoleted because it represents a molecular function.	GO:0000165|GO:0043539				True				biological_process											owl:Class	
GO:1902660	biolink:NamedThing	negative regulation of glucose mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway.	got7fsn_ti	downregulation of glucose mediated signalling|down regulation of glucose mediated signalling|down-regulation of glucose mediated signalling|negative regulation of glucose mediated signalling|down-regulation of glucose mediated signaling pathway|inhibition of glucose mediated signaling pathway|inhibition of glucose mediated signalling|downregulation of glucose mediated signaling pathway|down regulation of glucose mediated signaling pathway						di	2014-01-28T17:54:31Z						biological_process											owl:Class	
GO:0010958	biolink:NamedThing	regulation of amino acid import across plasma membrane	Any process that modulates the frequency, rate or extent of amino acid import into a cell.	got7fsn_ti	regulation of amino acid import						tb	2009-05-06T11:33:12Z						biological_process											owl:Class	
GO:0052178	biolink:NamedThing	obsolete metabolism by symbiont of host cell wall chitin	OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0100043	biolink:NamedThing	obsolete negative regulation of cellular response to alkaline pH by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular response to alkaline pH.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1901723	biolink:NamedThing	negative regulation of cell proliferation involved in kidney development	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development.	got7fsn_ti	inhibition of cell proliferation involved in kidney development|down regulation of cell proliferation involved in kidney development|downregulation of cell proliferation involved in kidney development|down-regulation of cell proliferation involved in kidney development						krc	2012-12-27T19:30:35Z						biological_process											owl:Class	
GO:1900756	biolink:NamedThing	protein processing in phagocytic vesicle	Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation.	got7fsn_ti	protein maturation by proteolysis in phagocytic vesicle|protein processing in phagosome|protein maturation by peptide bond cleavage in phagocytic vesicle|protein maturation by peptide bond cleavage in phagosome|peptidolysis during protein maturation in phagosome|protein maturation by peptide bond hydrolysis in phagocytic vesicle|peptidolysis during protein maturation in phagocytic vesicle|protein maturation by proteolysis in phagosome|protein maturation by peptide bond hydrolysis in phagosome						rjd	2012-05-29T09:55:14Z						biological_process											owl:Class	
GO:0006802	biolink:NamedThing	obsolete catalase reaction	OBSOLETE. The processes involved in the induction or activation of catalase, an enzyme that catalyzes the conversion of H2O2 into H2O.	got7fsn_ti	hydroperoxidase reaction|catalase reaction				This term was made obsolete because it represents a molecular function.	GO:0004096				True				biological_process											owl:Class	
GO:1903057	biolink:NamedThing	negative regulation of melanosome organization	Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization.	got7fsn_ti	inhibition of melanosome organization and biogenesis|downregulation of melanosome organisation|downregulation of melanosome organization and biogenesis|inhibition of melanosome organization|down regulation of melanosome organization and biogenesis|down regulation of melanosome organisation|downregulation of melanosome organization|down regulation of melanosome organization|inhibition of melanosome organisation|negative regulation of melanosome organisation|down-regulation of melanosome organization|down-regulation of melanosome organization and biogenesis|down-regulation of melanosome organisation|negative regulation of melanosome organization and biogenesis				Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles.		rl	2014-05-27T13:27:55Z						biological_process											owl:Class	
GO:1905907	biolink:NamedThing	negative regulation of amyloid fibril formation	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation.	got7fsn_ti	inhibition of amyloid fibril assembly|down-regulation of amyloid structure formation|downregulation of amyloid fibril formation|down regulation of amyloid fibril formation|inhibition of amyloid structure formation|inhibition of amyloid fibril formation|downregulation of amyloid structure formation|down regulation of amyloid structure assembly|down regulation of amyloid fibril assembly|down-regulation of amyloid structure assembly|downregulation of amyloid fibril assembly|down regulation of amyloid structure formation|down-regulation of amyloid fibril formation|downregulation of amyloid structure assembly|inhibition of amyloid structure assembly|negative regulation of amyloid structure formation|down-regulation of amyloid fibril assembly|negative regulation of amyloid structure assembly|negative regulation of amyloid fibril assembly				Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases  (PMID:22817896).		bc	2017-02-03T15:43:56Z						biological_process											owl:Class	
GO:0042483	biolink:NamedThing	negative regulation of odontogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.	got7fsn_ti	negative regulation of tooth development|down regulation of odontogenesis|inhibition of odontogenesis|downregulation of odontogenesis|down-regulation of odontogenesis|negative regulation of odontogenesis of calcareous or chitinous tooth										GO:0042486			biological_process											owl:Class	
GO:0006677	biolink:NamedThing	glycosylceramide metabolic process	The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.	got7fsn_ti	glycosylceramide metabolism													biological_process											owl:Class	
GO:1900621	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling	OBSOLETE. Calcium-mediated signaling that results in regulation of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling|regulation of global transcription from Pol II promoter by calcium-mediated signaling|regulation of transcription from Pol II promoter by calcium-mediated signaling				This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0019722	bf	2012-05-18T01:00:39Z		True				biological_process											owl:Class	
GO:0097041	biolink:NamedThing	phenolic phthiocerol biosynthetic process	The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.	got7fsn_ti	phenolic phthiocerol synthesis|phenolphthiocerol biosynthesis|phenolic phthiocerol anabolism|phenolic phthiocerol biosynthesis|phenolic phthiocerol formation						pr	2011-04-15T01:25:59Z						biological_process											owl:Class	
GO:0030053	biolink:NamedThing	obsolete immunophilin	OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin.	got7fsn_ti	immunophilin				This term was made obsolete because it does not represent a molecular function.	GO:0003755				True				molecular_function											owl:Class	
GO:1900445	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.	got7fsn_ti	up regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|up-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|upregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|activation of filamentous growth of a population of unicellular organisms in response to biotic stimulus						di	2012-04-25T05:56:35Z						biological_process											owl:Class	
GO:0014066	biolink:NamedThing	regulation of phosphatidylinositol 3-kinase signaling	Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.	got7fsn_ti	regulation of phosphatidylinositol 3-kinase cascade|regulation of PI 3-kinase cascade|regulation of phosphoinositide 3-kinase cascade|regulation of PI3K cascade													biological_process											owl:Class	
GO:0062093	biolink:NamedThing	lysophagy	The selective autophagy process in which a damaged lysosome is degraded by macroautophagy.	got7fsn_ti							dph	2018-11-20T16:47:11Z						biological_process											owl:Class	
GO:0120199	biolink:NamedThing	cone photoreceptor outer segment	The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins.	got7fsn_ti							krc	2019-05-07T22:23:28Z						cellular_component											owl:Class	
GO:1902098	biolink:NamedThing	calcitriol binding	Binding to calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.	got7fsn_ti	1alpha,25-dihydroxycholecalciferol binding|hormonally active vitamin D3 binding|1alpha,25-dihydroxyvitamin D3 binding|1alpha,25(OH)2 vitamin D3 binding|1,25-dihydroxyvitamin D3 binding|1,25-dihydroxycholecalciferol binding|1alpha,25(OH)2D3 binding						bf	2013-05-02T09:41:15Z						molecular_function											owl:Class	
GO:0004889	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035337	biolink:NamedThing	fatty-acyl-CoA metabolic process	The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.	got7fsn_ti	fatty-acyl-CoA metabolism|fatty acyl CoA metabolic process						bf	2010-03-02T11:05:48Z						biological_process											owl:Class	
GO:0052239	biolink:NamedThing	obsolete negative chemotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative chemotaxis in other organism during symbiotic interaction|negative chemotaxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:2000114	biolink:NamedThing	regulation of establishment of cell polarity	Any process that modulates the frequency, rate or extent of establishment of cell polarity.	got7fsn_ti	regulation of bud site selection/establishment of cell polarity|regulation of cell polarization						dph	2010-09-16T01:22:36Z						biological_process											owl:Class	
GO:0043572	biolink:NamedThing	plastid fission	The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA.	got7fsn_ti														biological_process											owl:Class	
GO:1904932	biolink:NamedThing	negative regulation of cartilage condensation	Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation.	got7fsn_ti	inhibition of cartilage condensation|down-regulation of cartilage condensation|downregulation of cartilage condensation|down regulation of cartilage condensation						mr	2016-01-29T18:13:39Z						biological_process											owl:Class	
GO:0097607	biolink:NamedThing	obsolete negative regulation of nuclear envelope permeability	OBSOLETE. Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.	got7fsn_ti	negative regulation of nuclear membrane permeability				The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it.		pr	2014-05-14T15:43:47Z		True				biological_process											owl:Class	
GO:1901345	biolink:NamedThing	response to L-thialysine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.	got7fsn_ti	response to thialysine						mah	2012-09-07T13:22:49Z						biological_process											owl:Class	
GO:1905158	biolink:NamedThing	obsolete regulation of Factor XII activation	OBSOLETE. Any process that modulates the frequency, rate or extent of Factor XII activation.	got7fsn_ti	regulation of Hageman factor activation				This term was accidentally approved after TermGenie review.  It should not have been approved.		sl	2016-04-19T23:03:25Z		True				biological_process											owl:Class	
GO:1905551	biolink:NamedThing	negative regulation of protein localization to endoplasmic reticulum	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.	got7fsn_ti	downregulation of protein localization in ER|down-regulation of protein localization in endoplasmic reticulum|downregulation of protein localisation in endoplasmic reticulum|downregulation of protein localization in endoplasmic reticulum|negative regulation of protein localization in endoplasmic reticulum|down regulation of protein localisation in endoplasmic reticulum|downregulation of protein localization to endoplasmic reticulum|negative regulation of protein localization in ER|down regulation of protein localization in ER|down-regulation of protein localisation in endoplasmic reticulum|down regulation of protein localization in endoplasmic reticulum|negative regulation of protein localisation in endoplasmic reticulum|down-regulation of protein localization to endoplasmic reticulum|inhibition of protein localization to endoplasmic reticulum|down-regulation of protein localization in ER|inhibition of protein localization in ER|down regulation of protein localization to endoplasmic reticulum|inhibition of protein localisation in endoplasmic reticulum|inhibition of protein localization in endoplasmic reticulum						rz	2016-10-12T11:37:08Z						biological_process											owl:Class	
GO:0000759	biolink:NamedThing	obsolete cell morphogenesis involved in conjugation with mutual genetic exchange	OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation without cellular fusion.	got7fsn_ti	cellular morphogenesis involved in conjugation without cellular fusion				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0010776	biolink:NamedThing	meiotic mismatch repair involved in meiotic gene conversion	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.	got7fsn_ti														biological_process											owl:Class	
GO:0018899	biolink:NamedThing	1,2-dichloroethane metabolic process	The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.	got7fsn_ti	1,2-dichloroethane metabolism											UM-BBD_pathwayID:dce		biological_process											owl:Class	
GO:1902518	biolink:NamedThing	response to cyclophosphamide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:34:08Z						biological_process											owl:Class	
GO:0005479	biolink:NamedThing	obsolete vacuolar assembly	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	vacuolar assembly			GO:0007033	This term was made obsolete because it represents a biological process and not a molecular function.					True				molecular_function											owl:Class	
GO:1901548	biolink:NamedThing	positive regulation of synaptic vesicle lumen acidification	Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification.	got7fsn_ti	positive regulation of synaptic vesicle lumen pH reduction|up-regulation of synaptic vesicle lumen acidification|up regulation of synaptic vesicle lumen acidification|up-regulation of synaptic vesicle lumen pH reduction|upregulation of synaptic vesicle lumen pH reduction|activation of synaptic vesicle lumen pH reduction|activation of synaptic vesicle lumen acidification|positive regulation of proton loading|up regulation of synaptic vesicle lumen pH reduction|upregulation of synaptic vesicle lumen acidification						dsf	2012-10-26T16:09:32Z						biological_process											owl:Class	
GO:0001311	biolink:NamedThing	obsolete formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging	OBSOLETE. Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age.	got7fsn_ti	formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging|assembly of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging|formation of extrachromosomal circular ribosomal DNA by homologous recombination during replicative cell aging|formation of extrachromosomal circular rDNA by homologous recombination during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0035110	biolink:NamedThing	obsolete leg morphogenesis	OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands.	got7fsn_ti	leg morphogenesis				This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0007480|GO:0035108|GO:0035137				True				biological_process											owl:Class	
GO:1905184	biolink:NamedThing	positive regulation of protein serine/threonine phosphatase activity	Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity.	got7fsn_ti	activation of serine/threonine specific protein phosphatase activity|up regulation of serine/threonine specific protein phosphatase activity|up-regulation of serine/threonine specific protein phosphatase activity|upregulation of serine/threonine specific protein phosphatase activity|positive regulation of serine/threonine specific protein phosphatase activity|up-regulation of protein serine/threonine phosphatase activity|upregulation of protein serine/threonine phosphatase activity|up regulation of protein serine/threonine phosphatase activity|activation of protein serine/threonine phosphatase activity						mah	2016-05-10T15:28:13Z						biological_process											owl:Class	
CHEBI:24838	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904304	biolink:NamedThing	regulation of gastro-intestinal system smooth muscle contraction	Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.	got7fsn_ti							sl	2015-06-09T23:18:42Z						biological_process											owl:Class	
GO:0075106	biolink:NamedThing	obsolete modulation by symbiont of host adenylate cyclase activity	OBSOLETE. Any process in which the symbiont modulates the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	Modulation by symbiont of host adenylyl cyclase activity|Modulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity|Modulation by symbiont of host adenylylcyclase activity|Modulation by symbiont of host ATP pyrophosphate-lyase activity|Modulation by symbiont of host 3',5'-cyclic AMP synthetase activity|Modulation by symbiont of host adenyl cyclase activity|Modulation by symbiont of host cAMP generating peptide activity|Modulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0032561	biolink:NamedThing	guanyl ribonucleotide binding	Binding to a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	got7fsn_ti														molecular_function											owl:Class	
GO:0032642	biolink:NamedThing	regulation of chemokine production	Any process that modulates the frequency, rate, or extent of chemokine production.	got7fsn_ti	regulation of chemokine secretion|regulation of chemokine biosynthetic process							2009-12-18T11:28:00Z			GO:0045073|GO:0090196			biological_process											owl:Class	
GO:1901057	biolink:NamedThing	trimethylenediamine biosynthetic process	The chemical reactions and pathways resulting in the formation of trimethylenediamine.	got7fsn_ti	trimethylenediamine biosynthesis|trimethylenediamine anabolism|trimethylenediamine formation|trimethylenediamine synthesis						yaf	2012-06-28T04:53:14Z						biological_process											owl:Class	
GO:0042788	biolink:NamedThing	polysomal ribosome	A ribosome bound to mRNA that forms part of a polysome.	got7fsn_ti	active ribosome													cellular_component											owl:Class	
GO:0010221	biolink:NamedThing	negative regulation of vernalization response	Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.	got7fsn_ti	down regulation of vernalization response|down-regulation of vernalization response|downregulation of vernalization response|inhibition of vernalization response													biological_process											owl:Class	
GO:1901432	biolink:NamedThing	negative regulation of response to cycloalkane	Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane.	got7fsn_ti	down-regulation of response to cycloalkane|inhibition of response to cycloalkane|down regulation of response to cycloalkane|downregulation of response to cycloalkane						tt	2012-10-01T21:03:08Z						biological_process											owl:Class	
GO:1900415	biolink:NamedThing	obsolete regulation of fungal-type cell wall biogenesis by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of fungal-type cell wall biogenesis.	got7fsn_ti	regulation of chitin- and beta-glucan-containing cell wall biogenesis by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T03:42:27Z		True				biological_process											owl:Class	
GO:0140461	biolink:NamedThing	obsolete subtelomeric heterochromatin organization	OBSOLETE. The organization of chromatin into heterochromatin at the subtelomeric region of a chromosome.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22043|https://github.com/geneontology/go-ontology/issues/19396			This term has been obsoleted because it represents a different process, GO:0097240 attachment of telomeric heterochromatin to nuclear envelope.		pg	2020-05-06T07:46:53Z		True				biological_process											owl:Class	
CHEBI:64600	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071687	biolink:NamedThing	obsolete horsetail nucleus leading edge	OBSOLETE. The part of the horsetail nucleus where telomeres cluster under the SPB and that leads horsetail movement. The horsetail nucleus is the elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.	got7fsn_ti					This term was made obsolete at the request of PomBase as the concept can be expressed by annotating to a less granular term and using annotation extensions.		mah	2010-02-22T05:04:40Z		True				cellular_component											owl:Class	
GO:0061385	biolink:NamedThing	fibroblast proliferation involved in heart morphogenesis	The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.	got7fsn_ti							dph	2011-02-10T01:41:59Z						biological_process											owl:Class	
GO:1903482	biolink:NamedThing	positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	Any process that activates or increases the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti	upregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|up-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|activation of actin filament organization involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|positive regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|upregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|activation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|positive regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|upregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|up-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|activation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis						vw	2014-09-23T16:03:59Z						biological_process											owl:Class	
GO:1901112	biolink:NamedThing	actinorhodin biosynthetic process	The chemical reactions and pathways resulting in the formation of actinorhodin.	got7fsn_ti	actinorhodin anabolism|actinorhodin synthesis|actinorhodin formation|actinorhodin biosynthesis						yaf	2012-07-11T03:06:08Z						biological_process											owl:Class	
GO:0032690	biolink:NamedThing	negative regulation of interleukin-1 alpha production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production.	got7fsn_ti	down regulation of interleukin-1 alpha production|negative regulation of interleukin-1 alpha secretion|down-regulation of interleukin-1 alpha production|inhibition of interleukin-1 alpha production|negative regulation of interleukin-1 alpha biosynthetic process|downregulation of interleukin-1 alpha production|negative regulation of IL-1 alpha production										GO:0050712|GO:0050723			biological_process											owl:Class	
GO:1902664	biolink:NamedThing	positive regulation of peptidyl-L-cysteine S-palmitoylation	Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.	got7fsn_ti	activation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|upregulation of peptidyl-cysteine S-palmitoylation|upregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|up-regulation of peptidyl-L-cysteine S-palmitoylation|activation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|upregulation of peptidyl-L-cysteine S-palmitoylation|up regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|activation of peptidyl-L-cysteine S-palmitoylation|up-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up regulation of peptidyl-L-cysteine S-palmitoylation|up regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up-regulation of peptidyl-cysteine S-palmitoylation|activation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|up regulation of peptidyl-cysteine S-palmitoylation|positive regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|activation of peptidyl-cysteine S-palmitoylation|up-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|positive regulation of peptidyl-cysteine S-palmitoylation						mm2	2014-01-29T11:33:28Z						biological_process											owl:Class	
GO:1900980	biolink:NamedThing	regulation of phenazine biosynthetic process	Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.	got7fsn_ti	regulation of dibenzopyrazine biosynthesis|regulation of azophenylene biosynthesis|regulation of dibenzo-p-diazine biosynthetic process|regulation of dibenzopyrazine biosynthetic process|regulation of dibenzo-p-diazine biosynthesis|regulation of azophenylene biosynthetic process|regulation of acridizine biosynthesis|regulation of acridizine biosynthetic process						tt	2012-06-14T04:04:39Z						biological_process											owl:Class	
GO:0072757	biolink:NamedThing	cellular response to camptothecin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.	got7fsn_ti	cellular response to CPT						mah	2012-11-07T12:12:35Z						biological_process											owl:Class	
GO:0001321	biolink:NamedThing	obsolete age-dependent general metabolic decline involved in replicative cell aging	OBSOLETE. A process of general metabolic decline that arises in dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.	got7fsn_ti	age-dependent general metabolic decline involved in replicative cell aging|age-dependent general metabolic decline during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0009145	biolink:NamedThing	purine nucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine nucleoside triphosphate anabolism|purine nucleoside triphosphate synthesis|purine nucleoside triphosphate biosynthesis|purine nucleoside triphosphate formation													biological_process											owl:Class	
GO:0015459	biolink:NamedThing	potassium channel regulator activity	Binds to and modulates the activity of a potassium channel.	got7fsn_ti	potassium channel gating activity													molecular_function											owl:Class	
GO:1902299	biolink:NamedThing	pre-replicative complex assembly involved in cell cycle DNA replication	Any pre-replicative complex assembly that is involved in cell cycle DNA replication.	got7fsn_ti	pre-replication complex assembly involved in cell cycle DNA replication|pre-RC assembly involved in cell cycle DNA replication						jl	2013-07-10T11:47:28Z						biological_process											owl:Class	
GO:0023005	biolink:NamedThing	obsolete signal initiation by neurotransmitter	OBSOLETE. The process in which a neurotransmitter signal causes activation of a receptor.	got7fsn_ti	signal initiation by neurotransmitter				This term was made obsolete because the meaning of the term is ambiguous.	GO:0030594|GO:0007165		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0033631	biolink:NamedThing	cell-cell adhesion mediated by integrin	The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.	got7fsn_ti	cell-cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0099082	biolink:NamedThing	retrograde trans-synaptic signaling by neuropeptide	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide.	got7fsn_ti														biological_process											owl:Class	
GO:1990187	biolink:NamedThing	obsolete protein localization to mRNA	OBSOLETE. A process in which a protein is transported to, or maintained at mRNA.	got7fsn_ti	protein localization to mRNA				This term was obsoleted at the TermGenie Gatekeeper stage.		rb	2013-09-11T18:19:20Z		True				biological_process											owl:Class	
GO:0009189	biolink:NamedThing	deoxyribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	deoxyribonucleoside diphosphate synthesis|deoxyribonucleoside diphosphate anabolism|deoxyribonucleoside diphosphate biosynthesis|deoxyribonucleoside diphosphate formation													biological_process											owl:Class	
GO:0006153	biolink:NamedThing	obsolete purine nucleosidase reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	purine nucleosidase reaction			GO:0008477	This term was made obsolete because it represents a molecular function.					True				biological_process											owl:Class	
GO:0140159	biolink:NamedThing	borate export across plasma membrane	The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti							pg	2018-02-02T10:21:37Z						biological_process											owl:Class	
GO:2000309	biolink:NamedThing	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.	got7fsn_ti	positive regulation of RANKL production|positive regulation of TNFSF11 production						mah	2011-01-17T10:44:54Z						biological_process											owl:Class	
GO:0010744	biolink:NamedThing	positive regulation of macrophage derived foam cell differentiation	Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	got7fsn_ti														biological_process											owl:Class	
GO:2001244	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.	got7fsn_ti	positive regulation of intrinsic apoptosis|positive regulation of intrinsic apoptotic signalling pathway|positive regulation of intrinsic apoptotic pathway|positive regulation of mitochondrial-mediated apoptotic pathway						pr	2011-11-24T01:36:07Z						biological_process											owl:Class	
CHEBI:27093	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061401	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12739			This term was obsoleted because it represents a GO-CAM model.	GO:0071476|GO:0045944	dph	2012-01-10T09:43:08Z		True				biological_process											owl:Class	
GO:0046266	biolink:NamedThing	obsolete triethanolamine biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.	got7fsn_ti	triethanolamine synthesis|triethanolamine biosynthetic process|triethanolamine biosynthesis|triethanolamine anabolism|triethanolamine formation			GO:0018981	This term was made obsolete because triethanolamine is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0019021	biolink:NamedThing	obsolete DNA viral genome	OBSOLETE. A viral genome composed of deoxyribonucleic acid.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:0002528	biolink:NamedThing	regulation of vascular permeability involved in acute inflammatory response	Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.	got7fsn_ti	regulation of vascular permeability during acute inflammatory response													biological_process											owl:Class	
GO:1990803	biolink:NamedThing	obsolete protein phosphorylation involved in protein localization to spindle microtubule	OBSOLETE. Any protein phosphorylation process involved in localizing a protein to the spindle microtubule.	got7fsn_ti	protein amino acid phosphorylation involved in protein localization to spindle microtubule|protein phosphorylation involved in protein localisation to spindle microtubule|protein amino acid phosphorylation involved in protein localization in spindle microtubule|protein phosphorylation involved in protein localization in spindle microtubule|protein amino acid phosphorylation involved in protein localisation to spindle microtubule|protein amino acid phosphorylation involved in protein localisation in spindle microtubule|protein phosphorylation involved in protein localisation in spindle microtubule	https://github.com/geneontology/go-ontology/issues/14137			This term has been obsoleted because it represents a GO-CAM model.		rb	2015-07-16T21:09:07Z		True				biological_process											owl:Class	
GO:0070321	biolink:NamedThing	obsolete regulation of translation in response to nitrogen starvation	OBSOLETE. Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19092			This term was obsoleted because it was redundant with GO:1903832 ; regulation of cellular response to amino acid starvation.	GO:1903832				True				biological_process											owl:Class	
GO:2000930	biolink:NamedThing	regulation of cellobiose metabolic process	Any process that modulates the frequency, rate or extent of cellobiose metabolic process.	got7fsn_ti	regulation of cellobiose metabolism						tt	2011-08-01T12:42:53Z						biological_process											owl:Class	
GO:0051857	biolink:NamedThing	obsolete growth or development of organism on or near symbiont surface	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of organism during interaction with symbiont|growth or development of organism on or near symbiont surface					GO:0032502				True				biological_process											owl:Class	
GO:1903600	biolink:NamedThing	glutaminase complex	A protein complex which is capable of glutaminase activity.	got7fsn_ti	Sno1p-Snz1p						ew	2014-11-11T18:41:42Z						cellular_component											owl:Class	
GO:0071263	biolink:NamedThing	negative regulation of translational initiation in response to starvation	Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment.	got7fsn_ti	downregulation of translation initiation in response to starvation|down-regulation of translation initiation in response to starvation|inhibition of translation initiation in response to starvation|negative regulation of translational initiation in response to nutrient starvation|down regulation of translation initiation in response to starvation						mah	2009-12-08T05:33:12Z						biological_process											owl:Class	
GO:0046053	biolink:NamedThing	dAMP metabolic process	The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).	got7fsn_ti	dAMP metabolism													biological_process											owl:Class	
GO:0019873	biolink:NamedThing	obsolete tellurium sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	tellurium sensitivity/resistance			GO:0046690	This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0140626	biolink:NamedThing	opioid growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of an opioid growth factor receptor binding to its physiological ligand, opioid growth factor (OGF, met-enkephalin). The OGF-OGFr complex leads to the increase in the synthesis of the selective cyclin-dependent kinase (CDK) inhibitor proteins, p12 (POLD4) and p16 (CDKN2A).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21110			Note that this term represents the activation of the zeta-opioid receptor. Do not confuse with GO:0038003 ; G protein-coupled opioid receptor signaling pathway, activated by the delta, kappa, mu, and nociceptin opioid receptors.		pg	2021-03-18T08:30:43Z				Wikipedia:OGFr|Wikipedia:Opioid_receptor		biological_process											owl:Class	
GO:0045225	biolink:NamedThing	negative regulation of CD4 production	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.	got7fsn_ti	negative regulation of CD4 formation|down-regulation of CD4 biosynthetic process|downregulation of CD4 biosynthetic process|down regulation of CD4 biosynthetic process|inhibition of CD4 biosynthetic process|negative regulation of CD4 anabolism|negative regulation of CD4 biosynthesis|negative regulation of CD4 synthesis|negative regulation of CD4 biosynthetic process													biological_process											owl:Class	
GO:0002609	biolink:NamedThing	positive regulation of myeloid dendritic cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.	got7fsn_ti	activation of myeloid dendritic cell antigen processing and presentation|up-regulation of myeloid dendritic cell antigen processing and presentation|upregulation of myeloid dendritic cell antigen processing and presentation|stimulation of myeloid dendritic cell antigen processing and presentation|up regulation of myeloid dendritic cell antigen processing and presentation													biological_process											owl:Class	
CHEBI:35391	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900662	biolink:NamedThing	negative regulation of emericellamide A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process.	got7fsn_ti	inhibition of emericellamide A formation|down regulation of emericellamide A biosynthetic process|down regulation of emericellamide A biosynthesis|down-regulation of emericellamide A biosynthesis|down regulation of emericellamide A anabolism|inhibition of emericellamide A anabolism|downregulation of emericellamide A biosynthetic process|negative regulation of emericellamide A biosynthesis|down regulation of emericellamide A formation|negative regulation of emericellamide A synthesis|inhibition of emericellamide A synthesis|inhibition of emericellamide A biosynthetic process|downregulation of emericellamide A anabolism|inhibition of emericellamide A biosynthesis|down-regulation of emericellamide A formation|negative regulation of emericellamide A formation|down-regulation of emericellamide A biosynthetic process|down regulation of emericellamide A synthesis|down-regulation of emericellamide A synthesis|downregulation of emericellamide A synthesis|negative regulation of emericellamide A anabolism|down-regulation of emericellamide A anabolism|downregulation of emericellamide A biosynthesis|downregulation of emericellamide A formation						di	2012-05-22T04:13:28Z						biological_process											owl:Class	
GO:0009115	biolink:NamedThing	xanthine catabolic process	The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.	got7fsn_ti	xanthine catabolism|xanthine oxidation|xanthine breakdown|xanthine degradation										GO:0006151			biological_process											owl:Class	
GO:1900977	biolink:NamedThing	regulation of tatiopterin metabolic process	Any process that modulates the frequency, rate or extent of tatiopterin metabolic process.	got7fsn_ti	regulation of tatiopterin metabolism						tt	2012-06-14T04:03:06Z						biological_process											owl:Class	
GO:1905684	biolink:NamedThing	regulation of plasma membrane repair	Any process that modulates the frequency, rate or extent of plasma membrane repair.	got7fsn_ti							bhm	2016-11-14T10:30:31Z						biological_process											owl:Class	
GO:1901801	biolink:NamedThing	1,5-anhydro-D-fructose metabolic process	The chemical reactions and pathways involving 1,5-anhydro-D-fructose.	got7fsn_ti	1,5-anhydro-D-fructose metabolism						yaf	2013-01-22T09:56:20Z						biological_process											owl:Class	
GO:1900512	biolink:NamedThing	regulation of starch utilization system complex assembly	Any process that modulates the frequency, rate or extent of starch utilization system complex assembly.	got7fsn_ti	regulation of SUS complex assembly|regulation of assembly of starch utilization system complex						tt	2012-05-02T04:06:44Z						biological_process											owl:Class	
GO:0060721	biolink:NamedThing	regulation of spongiotrophoblast cell proliferation	Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation.	got7fsn_ti							dph	2009-06-11T09:57:27Z						biological_process											owl:Class	
GO:0045709	biolink:NamedThing	negative regulation of adult salivary gland boundary specification	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism.	got7fsn_ti	negative regulation of adult salivary gland determination|downregulation of adult salivary gland determination|inhibition of adult salivary gland determination|down-regulation of adult salivary gland determination|down regulation of adult salivary gland determination													biological_process											owl:Class	
GO:0086011	biolink:NamedThing	membrane repolarization during action potential	The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	got7fsn_ti							tb	2011-11-10T08:15:05Z						biological_process											owl:Class	
GO:0046259	biolink:NamedThing	obsolete trinitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it.	got7fsn_ti	trinitrotoluene biosynthesis|trinitrotoluene anabolism|trinitrotoluene synthesis|trinitrotoluene formation|trinitrotoluene biosynthetic process			GO:0018973	This term was made obsolete because trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1990857	biolink:NamedThing	obsolete APC-Fzr1/Mfr1 complex	OBSOLETE. An anaphase promoting complex bound to an activator in the Fzr1 (human)/Mfr1 (pombe) family.	got7fsn_ti					This term was made obsolete because it is too fine-grained for GO.	GO:0005680	al	2015-09-22T13:29:11Z		True				cellular_component											owl:Class	
GO:1902130	biolink:NamedThing	(+)-lariciresinol metabolic process	The chemical reactions and pathways involving (+)-lariciresinol.	got7fsn_ti	(+)-lariciresinol metabolism						ms	2013-05-21T08:49:49Z						biological_process											owl:Class	
UBERON:0000016	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045964	biolink:NamedThing	positive regulation of dopamine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.	got7fsn_ti	up-regulation of dopamine metabolic process|stimulation of dopamine metabolic process|activation of dopamine metabolic process|positive regulation of dopamine metabolism|upregulation of dopamine metabolic process|up regulation of dopamine metabolic process													biological_process											owl:Class	
GO:0009175	biolink:NamedThing	pyrimidine ribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside monophosphate catabolism|pyrimidine ribonucleoside monophosphate degradation|pyrimidine ribonucleoside monophosphate breakdown													biological_process											owl:Class	
GO:0052507	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont SA-mediated signal transduction pathway|upregulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|induction by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|induction by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1903094	biolink:NamedThing	negative regulation of protein K48-linked deubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination.	got7fsn_ti	downregulation of protein K48-linked deubiquitination|inhibition of protein K48-linked deubiquitination|down regulation of protein K48-linked deubiquitination|down-regulation of protein K48-linked deubiquitination						bf	2014-06-03T12:27:54Z						biological_process											owl:Class	
GO:1990300	biolink:NamedThing	cellulosome binding	Binding to a cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides.	got7fsn_ti	scaffoldin complex binding							2014-02-26T22:41:22Z			GO:1990301			molecular_function											owl:Class	
GO:1905344	biolink:NamedThing	prostaglandin catabolic process	The chemical reactions and pathways resulting in the breakdown of prostaglandin.	got7fsn_ti	prostaglandin degradation|prostaglandin catabolism|prostaglandin breakdown						rl	2016-07-31T08:20:02Z						biological_process											owl:Class	
GO:0055088	biolink:NamedThing	lipid homeostasis	Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0036425	biolink:NamedThing	obsolete D-phosphoserine phosphatase activity	OBSOLETE. Catalysis of the reaction: O-phospho-D-serine + H2O = L-serine + phosphate, on a free amino acid.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21638			This term was obsoleted because there is no evidence that this function exisis. This reaction corresponds to RHEA:24873 and KEGG_REACTION:R02853.	GO:0036424	bf	2013-09-16T13:02:43Z		True				molecular_function											owl:Class	
GO:1900301	biolink:NamedThing	negative regulation of laminarabiose transport	Any process that stops, prevents or reduces the frequency, rate or extent of laminarabiose transport.	got7fsn_ti	down regulation of laminarabiose transport|down-regulation of laminarabiose transport|inhibition of laminarabiose transport|downregulation of laminarabiose transport						tt	2012-04-05T07:57:28Z						biological_process											owl:Class	
GO:1904531	biolink:NamedThing	positive regulation of actin filament binding	Any process that activates or increases the frequency, rate or extent of actin filament binding.	got7fsn_ti	up-regulation of actin filament binding|up regulation of F-actin binding|up-regulation of actin cross-linking activity|up regulation of actin cross-linking activity|upregulation of actin cross-linking activity|positive regulation of F-actin binding|up-regulation of F-actin binding|upregulation of F-actin binding|positive regulation of actin cross-linking activity|activation of F-actin binding|upregulation of actin filament binding|up regulation of actin filament binding|activation of actin filament binding|activation of actin cross-linking activity						als	2015-07-30T10:42:01Z						biological_process											owl:Class	
GO:1902524	biolink:NamedThing	positive regulation of protein K48-linked ubiquitination	Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination.	got7fsn_ti	up regulation of protein K48-linked polyubiquitination|upregulation of protein K48-linked polyubiquitination|activation of protein K48-linked ubiquitination|positive regulation of protein K48-linked polyubiquitination|up-regulation of protein K48-linked polyubiquitination|up regulation of protein K48-linked ubiquitination|activation of protein K48-linked polyubiquitination|up-regulation of protein K48-linked ubiquitination|upregulation of protein K48-linked ubiquitination				An example is BIRC2 (UniProt ID Q13490) in PMID:21931591.		ppm	2013-12-02T09:56:40Z						biological_process											owl:Class	
CHEBI:13390	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905679	biolink:NamedThing	positive regulation of adaptive immune effector response	Any process that activates or increases the frequency, rate or extent of adaptive immune effector response.	got7fsn_ti	up-regulation of adaptive immune effector response|upregulation of adaptive immune effector response|up regulation of adaptive immune effector response|activation of adaptive immune effector response						tb	2016-11-11T22:25:13Z						biological_process											owl:Class	
GO:1904676	biolink:NamedThing	negative regulation of somatic stem cell division	Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division.	got7fsn_ti	negative regulation of somatic stem cell renewal|down regulation of somatic stem cell renewal|downregulation of somatic stem cell renewal|down regulation of somatic stem cell division|inhibition of somatic stem cell renewal|inhibition of somatic stem cell division|downregulation of somatic stem cell division|down-regulation of somatic stem cell division|down-regulation of somatic stem cell renewal						rph	2015-09-14T08:47:28Z						biological_process											owl:Class	
GO:0100006	biolink:NamedThing	obsolete positive regulation of sulfite transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfite transport.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1905592	biolink:NamedThing	negative regulation of optical nerve axon regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration.	got7fsn_ti	down regulation of optical nerve axon regeneration|inhibition of optical nerve axon regeneration|down-regulation of optical nerve axon regeneration|downregulation of optical nerve axon regeneration						pga	2016-10-25T12:58:50Z						biological_process											owl:Class	
GO:2000126	biolink:NamedThing	negative regulation of octopamine or tyramine signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway.	got7fsn_ti	negative regulation of octopamine or tyramine signalling pathway|negative regulation of octopamine/tyramine signaling pathway						mah	2010-09-29T09:27:16Z						biological_process											owl:Class	
GO:1905778	biolink:NamedThing	negative regulation of exonuclease activity	Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity.	got7fsn_ti	down-regulation of exonuclease activity|down regulation of exonuclease IX activity|down regulation of exonuclease activity|down-regulation of exonuclease IX activity|inhibition of exonuclease IX activity|downregulation of exonuclease activity|negative regulation of exonuclease IX activity|inhibition of exonuclease activity|downregulation of exonuclease IX activity						nc	2016-12-21T21:32:16Z						biological_process											owl:Class	
GO:1990547	biolink:NamedThing	mitochondrial phosphate ion transmembrane transport	The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T11:50:19Z						biological_process											owl:Class	
GO:0035968	biolink:NamedThing	obsolete regulation of sterol import by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of sterol import, by regulation of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of sterol uptake by regulation of transcription from Pol II promoter|regulation of sterol import by regulation of transcription from Pol II promoter|regulation of sterol influx by regulation of transcription from RNA polymerase II promoter|regulation of sterol uptake by regulation of transcription from RNA polymerase II promoter|regulation of sterol influx by regulation of transcription from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:1905615	biolink:NamedThing	positive regulation of developmental vegetative growth	Any process that activates or increases the frequency, rate or extent of developmental vegetative growth.	got7fsn_ti	upregulation of developmental vegetative growth|up regulation of developmental vegetative growth|up-regulation of developmental vegetative growth|activation of developmental vegetative growth						pga	2016-10-28T11:45:28Z						biological_process											owl:Class	
GO:0015673	biolink:NamedThing	silver ion transport	The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	silver transport													biological_process											owl:Class	
GO:1903944	biolink:NamedThing	negative regulation of hepatocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process.	got7fsn_ti	down-regulation of hepatocyte apoptosis|inhibition of hepatocyte apoptotic process|downregulation of hepatocyte apoptotic process|down-regulation of hepatocyte apoptotic process|downregulation of hepatocyte apoptosis|down regulation of hepatocyte apoptotic process|negative regulation of hepatocyte apoptosis|down regulation of hepatocyte apoptosis|inhibition of hepatocyte apoptosis						sl	2015-02-19T12:54:50Z						biological_process											owl:Class	
GO:0045886	biolink:NamedThing	negative regulation of synaptic assembly at neuromuscular junction	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction.	got7fsn_ti	negative regulation of synaptic growth at neuromuscular junction|down-regulation of synaptic growth at neuromuscular junction|inhibition of synaptic growth at neuromuscular junction|downregulation of synaptic growth at neuromuscular junction|down regulation of synaptic growth at neuromuscular junction													biological_process											owl:Class	
GO:0010987	biolink:NamedThing	negative regulation of high-density lipoprotein particle clearance	Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							tb	2009-06-01T12:09:36Z						biological_process											owl:Class	
GO:1990611	biolink:NamedThing	regulation of cytoplasmic translational initiation in response to stress	Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti							vw	2015-01-20T13:04:14Z						biological_process											owl:Class	
GO:0002653	biolink:NamedThing	negative regulation of tolerance induction dependent upon immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response.	got7fsn_ti	inhibition of tolerance induction dependent upon immune response|down-regulation of tolerance induction dependent upon immune response|downregulation of tolerance induction dependent upon immune response|down regulation of tolerance induction dependent upon immune response|negative regulation of immune response-dependent tolerance induction													biological_process											owl:Class	
GO:1901086	biolink:NamedThing	benzylpenicillin metabolic process	The chemical reactions and pathways involving benzylpenicillin.	got7fsn_ti	penicillin G metabolism|benzylpenicillin metabolism						yaf	2012-07-05T10:28:33Z						biological_process											owl:Class	
GO:1902276	biolink:NamedThing	regulation of pancreatic amylase secretion	Any process that modulates the frequency, rate or extent of pancreatic amylase secretion.	got7fsn_ti							bf	2013-07-03T12:15:20Z						biological_process											owl:Class	
GO:0046410	biolink:NamedThing	obsolete 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity	OBSOLETE. Catalysis of the reaction: 2-oxoglutarate + isochorismate = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate + CO2.	got7fsn_ti	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity				This term was made obsolete because it was derived from an EC entry (EC:2.5.1.64) that has since been split into two entries.	GO:0070205|GO:0070204				True				molecular_function											owl:Class	
GO:1900649	biolink:NamedThing	regulation of dehydroaustinol biosynthetic process	Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process.	got7fsn_ti	regulation of dehydroaustinol anabolism|regulation of dehydroaustinol biosynthesis|regulation of dehydroaustinol formation|regulation of dehydroaustinol synthesis						di	2012-05-22T04:06:03Z						biological_process											owl:Class	
GO:1900647	biolink:NamedThing	negative regulation of chanoclavine-I aldehyde biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.	got7fsn_ti	down regulation of chanoclavine-I aldehyde biosynthesis|negative regulation of chanoclavine-I aldehyde formation|inhibition of chanoclavine-I aldehyde formation|downregulation of chanoclavine-I aldehyde biosynthetic process|downregulation of chanoclavine-I aldehyde synthesis|negative regulation of chanoclavine-I aldehyde biosynthesis|inhibition of chanoclavine-I aldehyde biosynthesis|down regulation of chanoclavine-I aldehyde biosynthetic process|downregulation of chanoclavine-I aldehyde biosynthesis|down regulation of chanoclavine-I aldehyde formation|down-regulation of chanoclavine-I aldehyde anabolism|negative regulation of chanoclavine-I aldehyde synthesis|down regulation of chanoclavine-I aldehyde anabolism|down-regulation of chanoclavine-I aldehyde synthesis|downregulation of chanoclavine-I aldehyde formation|inhibition of chanoclavine-I aldehyde synthesis|down-regulation of chanoclavine-I aldehyde biosynthesis|inhibition of chanoclavine-I aldehyde anabolism|down-regulation of chanoclavine-I aldehyde formation|negative regulation of chanoclavine-I aldehyde anabolism|down regulation of chanoclavine-I aldehyde synthesis|downregulation of chanoclavine-I aldehyde anabolism|inhibition of chanoclavine-I aldehyde biosynthetic process|down-regulation of chanoclavine-I aldehyde biosynthetic process						di	2012-05-22T04:04:59Z						biological_process											owl:Class	
GO:1905655	biolink:NamedThing	negative regulation of artery smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction.	got7fsn_ti	down regulation of artery smooth muscle contraction|down-regulation of artery smooth muscle contraction|downregulation of artery smooth muscle contraction|inhibition of artery smooth muscle contraction						rph	2016-11-09T12:34:53Z						biological_process											owl:Class	
GO:0015419	biolink:NamedThing	ABC-type sulfate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in).	got7fsn_ti	sulphate transporting ATPase activity|sulfate ABC transporter|sulfate transmembrane-transporting ATPase activity|ATPase-coupled sulfate transmembrane transporter activity|sulfate-transporting ATPase activity|sulfate/thiosulfate porter activity											MetaCyc:3.6.3.25-RXN|EC:7.3.2.3|RHEA:10192		molecular_function											owl:Class	
CHEBI:59924	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061950	biolink:NamedThing	negative regulation of premature acrosome loss	Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.	got7fsn_ti	negative regulation of spontaneous acrosome loss						dph	2017-10-25T17:56:47Z						biological_process											owl:Class	
GO:0045024	biolink:NamedThing	obsolete peptidyl-glutamyl peptide hydrolyzing enzyme activity	OBSOLETE. Catalysis of the cleavage of bonds after acidic amino acids and after branched chain amino acids.	got7fsn_ti	peptidyl-glutamyl peptide hydrolyzing enzyme activity			GO:0008233	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0008229	biolink:NamedThing	obsolete opsonin activity	OBSOLETE. Binds to microorganisms or other particulate material (for example, foreign erythrocytes) to increase the susceptibility of the latter to phagocytosis.	got7fsn_ti	opsonin activity				This term was made obsolete because it represents a class of gene products.	GO:0003823				True				molecular_function											owl:Class	
GO:0015377	biolink:NamedThing	cation:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).	got7fsn_ti	cation:chloride cotransporter activity													molecular_function											owl:Class	
GO:0033574	biolink:NamedThing	response to testosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.	got7fsn_ti	response to testosterone stimulus													biological_process											owl:Class	
GO:0009126	biolink:NamedThing	purine nucleoside monophosphate metabolic process	The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine nucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0019606	biolink:NamedThing	2-oxobutyrate catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.	got7fsn_ti	alpha-ketobutyrate catabolism|2-oxobutyrate breakdown|alpha-ketobutyrate catabolic process|2-oxobutyrate catabolism|2-oxobutyrate degradation											MetaCyc:2OXOBUTYRATECAT-PWY		biological_process											owl:Class	
GO:1903058	biolink:NamedThing	positive regulation of melanosome organization	Any process that activates or increases the frequency, rate or extent of melanosome organization.	got7fsn_ti	activation of melanosome organisation|up-regulation of melanosome organization and biogenesis|activation of melanosome organization and biogenesis|up-regulation of melanosome organization|positive regulation of melanosome organisation|up regulation of melanosome organisation|upregulation of melanosome organisation|up regulation of melanosome organization and biogenesis|activation of melanosome organization|upregulation of melanosome organization|positive regulation of melanosome organization and biogenesis|up regulation of melanosome organization|up-regulation of melanosome organisation|upregulation of melanosome organization and biogenesis				Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles.		rl	2014-05-27T13:28:01Z						biological_process											owl:Class	
GO:0090013	biolink:NamedThing	regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation	Any process that modulates the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak.	got7fsn_ti	regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation						tb	2009-07-29T10:54:44Z						biological_process											owl:Class	
UBERON:0000964	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034040	biolink:NamedThing	ATPase-coupled lipid transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).	got7fsn_ti	lipid-transporting ATPase activity|ATP-dependent lipid transmembrane transporter activity													molecular_function											owl:Class	
GO:1904250	biolink:NamedThing	positive regulation of age-related resistance	Any process that activates or increases the extent of age-related resistance.	got7fsn_ti	positive regulation of senescence-induced resistance|up-regulation of age-related resistance|up regulation of age-related resistance|up-regulation of adult seedling resistance|activation of ARR|up regulation of ARR|upregulation of flowering-induced resistance|up regulation of adult seedling resistance|positive regulation of ARR|upregulation of senescence-induced resistance|activation of age-related resistance|up-regulation of ARR|up regulation of senescence-induced resistance|upregulation of age-related resistance|upregulation of adult seedling resistance|upregulation of mature seedling resistance|up-regulation of flowering-induced resistance|positive regulation of flowering-induced resistance|up-regulation of senescence-induced resistance|activation of mature seedling resistance|up regulation of mature seedling resistance|upregulation of ARR|positive regulation of adult seedling resistance|activation of flowering-induced resistance|up-regulation of mature seedling resistance|activation of adult seedling resistance|positive regulation of mature seedling resistance|activation of senescence-induced resistance|up regulation of flowering-induced resistance						tb	2015-05-19T20:20:11Z						biological_process											owl:Class	
GO:1902564	biolink:NamedThing	negative regulation of neutrophil activation	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation.	got7fsn_ti	down-regulation of neutrophil activation|inhibition of neutrophil activation|downregulation of neutrophil activation|down regulation of neutrophil activation						ecu	2013-12-10T15:33:16Z						biological_process											owl:Class	
GO:0046591	biolink:NamedThing	obsolete embryonic leg joint morphogenesis	OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner.	got7fsn_ti	embryonic leg joint morphogenesis				This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0036023				True				biological_process											owl:Class	
GO:0051539	biolink:NamedThing	4 iron, 4 sulfur cluster binding	Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.	got7fsn_ti	iron-sulphur cluster 4Fe-4S binding|4 Fe 4 S cluster binding|tetrairon tetrasulphide cluster binding|4Fe-4S cluster binding|iron-sulfur cluster 4Fe-4S binding|4 iron, 4 sulphur cluster binding|tetrairon tetrasulfide cluster binding													molecular_function											owl:Class	
GO:0048685	biolink:NamedThing	negative regulation of collateral sprouting of intact axon in response to injury	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.	got7fsn_ti	down regulation of collateral sprouting of intact axon in response to injury|downregulation of collateral sprouting of intact axon in response to injury|down-regulation of collateral sprouting of intact axon in response to injury|inhibition of collateral sprouting of intact axon in response to injury													biological_process											owl:Class	
GO:0052340	biolink:NamedThing	obsolete catabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism by organism of cell wall cellulose in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0120246	biolink:NamedThing	acetylenic compound metabolic process	The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).	got7fsn_ti	alkyne substituted compound metabolism|alkyne substituted compound metabolic process	https://github.com/geneontology/go-ontology/issues/19842					krc	2020-08-18T00:54:23Z						biological_process											owl:Class	
GO:0061873	biolink:NamedThing	regulation of hepatic stellate cell contraction	Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction.	got7fsn_ti							dph	2017-05-01T13:26:49Z						biological_process											owl:Class	
GO:0100045	biolink:NamedThing	negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter	Any transcription from RNA polymerase II promoter process that negatively regulates arginine catabolic process.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
GO:0015006	biolink:NamedThing	obsolete plastocyanin	OBSOLETE. A copper-containing electron carrier acting between cytochrome b(6)-f and P700 of photosystem I.	got7fsn_ti	plastocyanin			GO:0046028	This term was made obsolete because it does not represent a molecular function.					True				molecular_function											owl:Class	
GO:1901445	biolink:NamedThing	regulation of response to propan-1-ol	Any process that modulates the frequency, rate or extent of response to propan-1-ol.	got7fsn_ti							tt	2012-10-02T14:12:46Z						biological_process											owl:Class	
GO:1904538	biolink:NamedThing	regulation of glycolytic process through fructose-6-phosphate	Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate.	got7fsn_ti	regulation of glycolysis through fructose-6-phosphate						dph	2015-08-07T11:35:10Z						biological_process											owl:Class	
GO:0061105	biolink:NamedThing	regulation of stomach neuroendocrine cell differentiation	Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.	got7fsn_ti							dph	2010-04-29T12:19:37Z						biological_process											owl:Class	
GO:1900850	biolink:NamedThing	negative regulation of pseurotin A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process.	got7fsn_ti	down regulation of pseurotin A biosynthetic process|downregulation of pseurotin A biosynthetic process|down-regulation of pseurotin A biosynthetic process						di	2012-06-07T09:45:49Z						biological_process											owl:Class	
GO:2000356	biolink:NamedThing	regulation of kidney smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation.	got7fsn_ti							yaf	2011-02-03T02:14:24Z						biological_process											owl:Class	
GO:0051397	biolink:NamedThing	obsolete N-terminal basic amino acid aminopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of basic amino acid residues at the N-terminal of an oligopeptide or polypeptide chain.	got7fsn_ti	N-terminal basic amino acid aminopeptidase activity			GO:0004177	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1901903	biolink:NamedThing	tyrocidine catabolic process	The chemical reactions and pathways resulting in the breakdown of tyrocidine.	got7fsn_ti	tyrocidine catabolism|tyrocidine degradation|tyrocidine breakdown						yaf	2013-02-12T23:40:34Z						biological_process											owl:Class	
GO:0061159	biolink:NamedThing	establishment of bipolar cell polarity involved in cell morphogenesis	The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.	got7fsn_ti							dph	2010-06-23T09:14:39Z						biological_process											owl:Class	
GO:1903005	biolink:NamedThing	negative regulation of protein K63-linked deubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination.	got7fsn_ti	downregulation of protein K63-linked deubiquitination|down regulation of protein K63-linked deubiquitination|down-regulation of protein K63-linked deubiquitination|inhibition of protein K63-linked deubiquitination						bf	2014-05-12T15:40:49Z						biological_process											owl:Class	
GO:0035961	biolink:NamedThing	obsolete positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of ergosterol anabolism by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by stimulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthetic process by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol synthesis by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthetic process by activation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol synthesis by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthetic process by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by up-regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0042965	biolink:NamedThing	obsolete glutaredoxin biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of a small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase.	got7fsn_ti	glutaredoxin formation|glutaredoxin anabolism|glutaredoxin biosynthesis|glutaredoxin synthesis				This term was made obsolete because it refers to the biosynthesis of a protein.					True				biological_process											owl:Class	
GO:2000879	biolink:NamedThing	negative regulation of dipeptide transport	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport.	got7fsn_ti							bf	2011-07-27T02:55:21Z						biological_process											owl:Class	
GO:1900658	biolink:NamedThing	regulation of emericellamide biosynthetic process	Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process.	got7fsn_ti	regulation of emericellamide anabolism|regulation of emericellamide biosynthesis|regulation of emericellamide formation|regulation of emericellamide synthesis						di	2012-05-22T04:10:19Z						biological_process											owl:Class	
GO:0150146	biolink:NamedThing	cell junction disassembly	The disaggregation of a cell junction into its constituent components.	got7fsn_ti							bc	2019-12-08T11:12:13Z						biological_process											owl:Class	
GO:1901879	biolink:NamedThing	regulation of protein depolymerization	Any process that modulates the frequency, rate or extent of protein depolymerization.	got7fsn_ti	regulation of protein polymer catabolic process|regulation of protein polymer breakdown|regulation of protein polymer catabolism|regulation of protein polymer degradation						rl	2013-02-06T13:57:23Z						biological_process											owl:Class	
GO:1900408	biolink:NamedThing	negative regulation of cellular response to oxidative stress	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress.	got7fsn_ti	down-regulation of adaptive response to oxidative stress|negative regulation of adaptive response to oxidative stress|down regulation of adaptive response to oxidative stress|downregulation of cellular response to oxidative stress|inhibition of adaptive response to oxidative stress|down-regulation of cellular response to oxidative stress|downregulation of adaptive response to oxidative stress|inhibition of cellular response to oxidative stress|down regulation of cellular response to oxidative stress						mah	2012-04-20T03:31:05Z						biological_process											owl:Class	
GO:0046007	biolink:NamedThing	negative regulation of activated T cell proliferation	Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.	got7fsn_ti	negative regulation of activated T lymphocyte proliferation|down regulation of activated T cell proliferation|negative regulation of activated T-lymphocyte proliferation|down-regulation of activated T cell proliferation|inhibition of activated T cell proliferation|downregulation of activated T cell proliferation|negative regulation of activated T-cell proliferation													biological_process											owl:Class	
GO:0075073	biolink:NamedThing	obsolete autophagy of symbiont cells on or near host surface	OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm, occurring when the symbiont is on or near its host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that this term did not represent any specific host/symbiont process.					True				biological_process											owl:Class	
CHEBI:17568	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905530	biolink:NamedThing	negative regulation of uracil import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane.	got7fsn_ti							vw	2016-10-05T21:03:48Z						biological_process											owl:Class	
GO:0008751	biolink:NamedThing	obsolete NAD(P)H dehydrogenase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	NAD(P)H dehydrogenase				This term was made obsolete because it is a redundant grouping term with only one child.	GO:0016651				True				molecular_function											owl:Class	
GO:2000093	biolink:NamedThing	regulation of mesonephric nephron tubule epithelial cell differentiation	Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.	got7fsn_ti							dph	2010-09-03T06:12:25Z						biological_process											owl:Class	
GO:0062086	biolink:NamedThing	regulation of vein smooth muscle contraction	Any process that modulates the frequency, rate or extent of vein smooth muscle contraction.	got7fsn_ti							dph	2018-11-02T15:17:26Z						biological_process											owl:Class	
GO:0006049	biolink:NamedThing	UDP-N-acetylglucosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-N-acetylglucosamine breakdown|UDP-N-acetylglucosamine degradation|UDP-N-acetylglucosamine catabolism													biological_process											owl:Class	
GO:0048297	biolink:NamedThing	negative regulation of isotype switching to IgA isotypes	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.	got7fsn_ti	negative regulation of class switch recombination to IgA isotypes|down-regulation of isotype switching to IgA isotypes|down regulation of isotype switching to IgA isotypes|negative regulation of class switching to IgA isotypes|downregulation of isotype switching to IgA isotypes|inhibition of isotype switching to IgA isotypes|negative regulation of isotype switch recombination to IgA isotypes													biological_process											owl:Class	
GO:2001253	biolink:NamedThing	regulation of histone H3-K36 trimethylation	Any process that modulates the frequency, rate or extent of histone H3-K36 trimethylation.	got7fsn_ti							pr	2011-12-06T07:38:09Z						biological_process											owl:Class	
GO:0016883	biolink:NamedThing	obsolete other carbon-nitrogen ligase activity	OBSOLETE. A grouping term for carbon-nitrogen ligases that cannot be more accurately categorized.	got7fsn_ti	other carbon-nitrogen ligase activity				This term was made obsolete because it was an unnecessary grouping term.	GO:0016879				True				molecular_function											owl:Class	
GO:0019032	biolink:NamedThing	obsolete viral glycoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	viral glycoprotein				This term was made obsolete because it represents a type of gene product and not a location or complex.	GO:0019031				True				cellular_component											owl:Class	
GO:0046146	biolink:NamedThing	tetrahydrobiopterin metabolic process	The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.	got7fsn_ti	tetrahydrobiopterin metabolism|5,6,7,8-tetrahydrobiopterin metabolic process													biological_process											owl:Class	
GO:1900405	biolink:NamedThing	obsolete regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of  cell separation after cytokinesis.	got7fsn_ti	regulation of cytokinetic cell separation by regulation of transcription from RNA polymerase II promoter						mah	2012-04-20T02:46:10Z		True				biological_process											owl:Class	
GO:1903647	biolink:NamedThing	negative regulation of chlorophyll catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process.	got7fsn_ti	inhibition of chlorophyll degradation|down-regulation of chlorophyll catabolism|down regulation of chlorophyll catabolism|inhibition of chlorophyll catabolism|down-regulation of chlorophyll breakdown|inhibition of chlorophyll catabolic process|negative regulation of chlorophyll breakdown|down regulation of chlorophyll degradation|downregulation of chlorophyll catabolic process|downregulation of chlorophyll breakdown|down regulation of chlorophyll breakdown|inhibition of chlorophyll breakdown|negative regulation of chlorophyll degradation|downregulation of chlorophyll degradation|downregulation of chlorophyll catabolism|down-regulation of chlorophyll catabolic process|down regulation of chlorophyll catabolic process|negative regulation of chlorophyll catabolism|down-regulation of chlorophyll degradation						tb	2014-11-22T00:18:25Z						biological_process											owl:Class	
GO:2001280	biolink:NamedThing	positive regulation of unsaturated fatty acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process.	got7fsn_ti	positive regulation of polyunsaturated fatty acid biosynthesis|positive regulation of unsaturated fatty acid anabolism|positive regulation of unsaturated fatty acid biosynthesis|positive regulation of unsaturated fatty acid synthesis|positive regulation of fatty acid desaturation|positive regulation of unsaturated fatty acid formation						dgf	2011-12-14T07:48:33Z						biological_process											owl:Class	
GO:1990628	biolink:NamedThing	obsolete Sigma-E factor negative regulation complex	OBSOLETE. A protein complex consisting of RseA, RseB and RpoE. It form the inactive form of the sigma-E transcription factor. In response to stress, outer membrane proteins accumulate in the periplasm and activate cleavage of RseA periplasmic domain by DegS, triggering a proteolytic cascade that frees sigma-E to activate gene expression. RseB binding to RseA prevents activated DegS from cleaving RseA. Sigma-E-mediated envelope stress response is the major pathway to ensure homeostasis in the envelope compartment of the cell.	got7fsn_ti	RseA-RseB-RpoE complex|Sigma-E factor negative regulation complex				This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2015-02-04T15:38:37Z		True				cellular_component											owl:Class	
GO:0075170	biolink:NamedThing	obsolete negative regulation of protein kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont protein kinase-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0002813	biolink:NamedThing	regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.	got7fsn_ti														biological_process											owl:Class	
GO:0032558	biolink:NamedThing	adenyl deoxyribonucleotide binding	Binding to an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	got7fsn_ti														molecular_function											owl:Class	
GO:1901967	biolink:NamedThing	negative regulation of cellular response to iron ion starvation	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation.	got7fsn_ti	inhibition of cellular response to iron ion starvation|downregulation of cellular response to iron ion starvation|down-regulation of cellular response to iron ion starvation|down regulation of cellular response to iron ion starvation						al	2013-02-21T11:36:02Z						biological_process											owl:Class	
GO:1901385	biolink:NamedThing	regulation of voltage-gated calcium channel activity	Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity.	got7fsn_ti	regulation of depolarization-activated voltage-gated calcium channel activity|regulation of voltage-gated calcium ion channel activity|regulation of depolarization-activated voltage gated calcium channel activity|regulation of voltage-dependent calcium channel activity|regulation of depolarization-activated calcium channel|regulation of depolarization-activated voltage-gated calcium channel|regulation of voltage-sensitive calcium channel|regulation of voltage gated calcium channel activity|regulation of dihydropyridine-sensitive calcium channel activity						vk	2012-10-01T10:34:08Z						biological_process											owl:Class	
GO:0097360	biolink:NamedThing	chorionic trophoblast cell proliferation	The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.	got7fsn_ti							pr	2012-07-19T10:17:37Z						biological_process											owl:Class	
GO:1901484	biolink:NamedThing	negative regulation of transcription factor catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of transcription factor catabolic process.	got7fsn_ti	downregulation of sequence-specific DNA binding transcription factor catabolic process|down-regulation of transcription factor catabolism|negative regulation of proteasome-mediated transcription factor catabolism|negative regulation of transcription factor breakdown|negative regulation of transcription factor degradation|inhibition of transcription factor degradation|down-regulation of proteasome-mediated transcription factor catabolism|down regulation of transcription factor breakdown|negative regulation of transcription factor catabolism|down regulation of proteasome-mediated transcription factor catabolism|down regulation of transcription factor catabolism|downregulation of transcription factor breakdown|downregulation of proteasome-mediated transcription factor catabolism|down regulation of transcription factor degradation|down-regulation of sequence-specific DNA binding transcription factor catabolic process|inhibition of transcription factor catabolic process|down regulation of sequence-specific DNA binding transcription factor catabolic process|downregulation of transcription factor degradation|down regulation of transcription factor catabolic process|down-regulation of transcription factor degradation|negative regulation of sequence-specific DNA binding transcription factor catabolic process|down-regulation of transcription factor breakdown|downregulation of transcription factor catabolism|inhibition of transcription factor breakdown|downregulation of transcription factor catabolic process|inhibition of proteasome-mediated transcription factor catabolism|inhibition of transcription factor catabolism|inhibition of sequence-specific DNA binding transcription factor catabolic process|down-regulation of transcription factor catabolic process						bf	2012-10-08T09:03:22Z						biological_process											owl:Class	
GO:0009173	biolink:NamedThing	pyrimidine ribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0061353	biolink:NamedThing	BMP signaling pathway involved in Malpighian tubule cell chemotaxis	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule.	got7fsn_ti	bone morphogenic protein receptor signalling pathway involved in Malpighian tubule cell chemotaxis						dph	2010-10-01T12:01:00Z						biological_process											owl:Class	
GO:1903137	biolink:NamedThing	regulation of cell wall integrity MAPK cascade	Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.	got7fsn_ti	regulation of Pmk1 MAPK cell integrity signaling|regulation of MAPKKK cascade involved in cell wall biogenesis|regulation of Mpk1 cascade|regulation of cell wall biogenesis, MAPKKK cascade|regulation of Slt2 cascade|regulation of MAPK cascade involved in cell wall organization or biogenesis|regulation of MAPK cascade involved in cell wall biogenesis|regulation of cell integrity MAPK pathway|regulation of PMK1-MAPK signal transduction pathway|regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway	https://github.com/geneontology/go-ontology/issues/20131					mah	2014-07-01T10:21:53Z						biological_process											owl:Class	
GO:0043287	biolink:NamedThing	poly(3-hydroxyalkanoate) binding	Binding to a poly(3-hydroxyalkanoate), a polyester of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.	got7fsn_ti	PHA binding													molecular_function											owl:Class	
GO:0009146	biolink:NamedThing	purine nucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine nucleoside triphosphate degradation|purine nucleoside triphosphate breakdown|purine nucleoside triphosphate catabolism													biological_process											owl:Class	
GO:1900925	biolink:NamedThing	positive regulation of glycine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of glycine import.	got7fsn_ti	upregulation of glycine import|up-regulation of glycine import|activation of glycine import|positive regulation of glycine import|up regulation of glycine import						al	2012-06-13T07:40:40Z						biological_process											owl:Class	
GO:1904999	biolink:NamedThing	positive regulation of leukocyte adhesion to arterial endothelial cell	Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.	got7fsn_ti	up-regulation of leukocyte adhesion to arterial endothelial cell|up regulation of leukocyte adhesion to arterial endothelial cell|upregulation of leukocyte adhesion to arterial endothelial cell|activation of leukocyte adhesion to arterial endothelial cell						bc	2016-03-01T11:05:05Z						biological_process											owl:Class	
GO:0062207	biolink:NamedThing	regulation of pattern recognition receptor signaling pathway	Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.	got7fsn_ti							dph	2020-02-03T14:38:53Z						biological_process											owl:Class	
CHEBI:25806	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0062102	biolink:NamedThing	female germline stem cell symmetric division	Division of a female germline stem cell to produce two germline stem cells of the same type as the parent.	got7fsn_ti							dph	2018-12-18T14:17:54Z						biological_process											owl:Class	
GO:0046285	biolink:NamedThing	flavonoid phytoalexin metabolic process	The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.	got7fsn_ti	flavonoid phytoalexin metabolism													biological_process											owl:Class	
GO:1905234	biolink:NamedThing	cellular response to codeine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.	got7fsn_ti							sl	2016-06-07T21:26:53Z						biological_process											owl:Class	
GO:0052387	biolink:NamedThing	obsolete induction by organism of symbiont apoptosis	OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of symbiont apoptosis|induction by organism of symbiont apoptotic programmed cell death|induction by organism of symbiont apoptosis|activation by organism of symbiont apoptotic programmed cell death				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1904384	biolink:NamedThing	cellular response to sodium phosphate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.	got7fsn_ti							sl	2015-06-23T16:55:13Z						biological_process											owl:Class	
GO:1904806	biolink:NamedThing	regulation of protein oxidation	Any process that modulates the frequency, rate or extent of protein oxidation.	got7fsn_ti	regulation of protein amino acid oxidation						mec	2015-11-10T14:06:00Z						biological_process											owl:Class	
GO:2000754	biolink:NamedThing	regulation of sphingomyelin catabolic process	Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process.	got7fsn_ti	regulation of sphingomyelin breakdown|regulation of sphingomyelin catabolism|regulation of sphingomyelin degradation						rl	2011-06-16T03:17:30Z						biological_process											owl:Class	
GO:1904993	biolink:NamedThing	obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle	OBSOLETE. Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in positive regulation of G2/M transition of mitotic cell cycle.	got7fsn_ti	up regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|upregulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|up regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|positive regulation of CDK activity involved in positive regulation of G2/M transition of mitotic cell cycle|activation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|stimulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|stimulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|upregulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|activation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|positive regulation of CDK activity involved in positive regulation of mitotic entry|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of mitotic entry				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2016-03-01T00:59:41Z		True				biological_process											owl:Class	
UBERON:0001752	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035736	biolink:NamedThing	cell proliferation involved in compound eye morphogenesis	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.	got7fsn_ti							bf	2011-03-17T10:57:03Z						biological_process											owl:Class	
GO:0071807	biolink:NamedThing	replication fork arrest involved in DNA replication termination	A replication fork arrest process that contributes to the termination of DNA replication.	got7fsn_ti							mah	2010-09-03T03:26:38Z						biological_process											owl:Class	
GO:0019566	biolink:NamedThing	arabinose metabolic process	The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.	got7fsn_ti	arabinose metabolism													biological_process											owl:Class	
GO:0034392	biolink:NamedThing	negative regulation of smooth muscle cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.	got7fsn_ti	inhibition of smooth muscle cell apoptosis|negative regulation of SMC apoptosis|downregulation of smooth muscle cell apoptosis|down regulation of smooth muscle cell apoptosis|negative regulation of smooth muscle cell apoptosis|down-regulation of smooth muscle cell apoptosis													biological_process											owl:Class	
GO:0001774	biolink:NamedThing	microglial cell activation	The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti														biological_process											owl:Class	
PR:000007557	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009489	biolink:NamedThing	obsolete rubredoxin	OBSOLETE. A low molecular weight mononuclear iron protein involved in electron transfer, with an iron tetrahedrally coordinated by the sulfurs of four conserved cysteine residues.	got7fsn_ti	rubredoxin			GO:0009055	This term was made obsolete because it does not represent a molecular function.					True				molecular_function											owl:Class	
GO:0071167	biolink:NamedThing	obsolete ribonucleoprotein complex import into nucleus	OBSOLETE. The directed movement of a ribonucleoprotein complex from the cytoplasm to the nucleus.	got7fsn_ti	ribonucleoprotein import into nucleus|ribonucleoprotein complex transport from cytoplasm to nucleus|ribonucleoprotein complex nucleus import|ribonucleoprotein complex import into cell nucleus|ribonucleoprotein complex targeting to nucleus|RNP import into nucleus				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606	mah	2009-11-19T04:48:42Z		True				biological_process											owl:Class	
GO:2000436	biolink:NamedThing	positive regulation of protein neddylation	Any process that activates or increases the frequency, rate or extent of protein neddylation.	got7fsn_ti	positive regulation of RUB1-protein conjugation						vw	2011-03-03T02:06:19Z						biological_process											owl:Class	
GO:0110066	biolink:NamedThing	negative regulation of interphase mitotic telomere clustering	Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase.	got7fsn_ti	negative regulation of mitotic telomere clustering during interphase|telomere dispersion during interphase						kmv	2017-11-17T22:11:59Z						biological_process											owl:Class	
GO:0019859	biolink:NamedThing	thymine metabolic process	The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.	got7fsn_ti	thymine metabolism													biological_process											owl:Class	
GO:1901429	biolink:NamedThing	negative regulation of syringal lignin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process.	got7fsn_ti	negative regulation of syringal lignin anabolism|downregulation of syringal lignin biosynthetic process|downregulation of syringal lignin formation|downregulation of syringal lignin biosynthesis|down regulation of syringal lignin formation|inhibition of syringal lignin biosynthetic process|down regulation of syringal lignin biosynthesis|negative regulation of syringal lignin synthesis|negative regulation of syringal lignin formation|down-regulation of S-lignin biosynthetic process|down-regulation of syringal lignin synthesis|negative regulation of S-lignin biosynthetic process|down regulation of syringal lignin biosynthetic process|downregulation of syringal lignin anabolism|down-regulation of syringal lignin anabolism|down regulation of syringal lignin anabolism|down regulation of S-lignin biosynthetic process|negative regulation of syringal lignin biosynthesis|downregulation of syringal lignin synthesis|downregulation of S-lignin biosynthetic process|down-regulation of syringal lignin biosynthetic process|inhibition of syringal lignin formation|inhibition of syringal lignin anabolism|down-regulation of syringal lignin formation|down-regulation of syringal lignin biosynthesis|down regulation of syringal lignin synthesis|inhibition of syringal lignin synthesis|inhibition of S-lignin biosynthetic process|inhibition of syringal lignin biosynthesis						tb	2012-10-01T20:14:51Z						biological_process											owl:Class	
GO:0052105	biolink:NamedThing	obsolete induction by symbiont of defense-related host cell wall thickening	OBSOLETE. The activation by an organism of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of host defensive cell wall thickening|induction by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|activation by symbiont of defense-related host cell wall thickening|upregulation by symbiont of defense-related host cell wall thickening|activation by organism of defense-related host cell wall thickening|positive regulation by symbiont of defense-related host cell wall thickening|up-regulation by symbiont of defense-related host cell wall thickening|positive regulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|positive regulation by organism of host defensive cell wall thickening|up regulation by symbiont of defense-related host cell wall thickening|induction by organism of host defensive cell wall thickening|stimulation by symbiont of defense-related host cell wall thickening				This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052538|GO:0052539|GO:0052290			biological_process											owl:Class	
GO:2000738	biolink:NamedThing	positive regulation of stem cell differentiation	Any process that activates or increases the frequency, rate or extent of stem cell differentiation.	got7fsn_ti							yaf	2011-06-14T02:05:23Z						biological_process											owl:Class	
GO:1905471	biolink:NamedThing	regulation of histone H3-K79 dimethylation	Any process that modulates the frequency, rate or extent of histone H3-K79 dimethylation.	got7fsn_ti	regulation of histone lysine H3 K79 dimethylation|regulation of histone H3 K79 dimethylation						hbye	2016-09-21T15:27:02Z						biological_process											owl:Class	
CHEBI:17700	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120072	biolink:NamedThing	positive regulation of pyloric antrum smooth muscle contraction	Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.	got7fsn_ti							krc	2017-06-13T23:32:56Z						biological_process											owl:Class	
GO:1905817	biolink:NamedThing	positive regulation of dorsal/ventral axon guidance	Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance.	got7fsn_ti	activation of dorsal/ventral axon guidance|up regulation of dorsal-ventral axon guidance|upregulation of dorsoventral axon guidance|activation of dorsoventral axon guidance|positive regulation of dorsal-ventral axon guidance|activation of dorsal-ventral axon guidance|up regulation of dorsal/ventral axon pathfinding|activation of dorsal/ventral axon pathfinding|up regulation of dorsal/ventral axon guidance|upregulation of dorsal/ventral axon pathfinding|up-regulation of dorsal/ventral axon pathfinding|up-regulation of dorsal-ventral axon guidance|upregulation of dorsal-ventral axon guidance|up regulation of dorsoventral axon guidance|positive regulation of dorsal/ventral axon pathfinding|up-regulation of dorsoventral axon guidance|up-regulation of dorsal/ventral axon guidance|upregulation of dorsal/ventral axon guidance|positive regulation of dorsoventral axon guidance						hbye	2017-01-12T13:39:01Z						biological_process											owl:Class	
GO:0015256	biolink:NamedThing	obsolete monocarboxylate channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	monocarboxylate channel activity				This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True				molecular_function											owl:Class	
GO:1901170	biolink:NamedThing	naphthalene catabolic process	The chemical reactions and pathways resulting in the breakdown of naphthalene.	got7fsn_ti	naphthalene breakdown|naphthalene degradation|naphthalene catabolism|naphthalene metabolism|naphthalene metabolic process	https://github.com/geneontology/go-ontology/issues/20974					yaf	2012-07-19T09:33:50Z			GO:0018931	UM-BBD_pathwayID:naph		biological_process											owl:Class	
GO:1905928	biolink:NamedThing	obsolete negative regulation of invadopodium disassembly	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium disassembly.	got7fsn_ti	down-regulation of invadopodium disassembly|inhibition of invadopodium disassembly|downregulation of invadopodium disassembly|down regulation of invadopodium disassembly				This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:39:05Z		True				biological_process											owl:Class	
GO:0060864	biolink:NamedThing	obsolete positive regulation of floral organ abscission by small GTPase mediated signal transduction	OBSOLETE. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that increases the rate or extent of floral organ abscission.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.		dph	2009-08-12T04:34:56Z		True				biological_process											owl:Class	
GO:2000410	biolink:NamedThing	regulation of thymocyte migration	Any process that modulates the frequency, rate or extent of thymocyte migration.	got7fsn_ti	regulation of immature T cell migration|regulation of immature T-lymphocyte migration|regulation of immature T lymphocyte migration|regulation of thymic lymphocyte migration|regulation of immature T-cell migration						mah	2011-02-23T01:33:32Z						biological_process											owl:Class	
GO:0075258	biolink:NamedThing	negative regulation of teliospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.	got7fsn_ti														biological_process											owl:Class	
GO:1901351	biolink:NamedThing	regulation of phosphatidylglycerol biosynthetic process	Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process.	got7fsn_ti	regulation of phosphatidylglycerol anabolism|regulation of phosphatidylglycerol biosynthesis|regulation of phosphatidylglycerol synthesis|regulation of phosphatidylglycerol formation						dgf	2012-09-12T20:46:37Z						biological_process											owl:Class	
GO:0034152	biolink:NamedThing	negative regulation of toll-like receptor 6 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway.	got7fsn_ti	negative regulation of TLR6 signaling pathway|negative regulation of toll-like receptor 6 signalling pathway													biological_process											owl:Class	
GO:0036402	biolink:NamedThing	proteasome-activating activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.	got7fsn_ti	proteasome channel opening activity|ATPase involved in positive regulation of proteasomal protein catabolic process|proteasome channel gating activity|proteasome-activating ATPase activity|proteasomal ATPase activity	https://github.com/geneontology/go-ontology/issues/20879					bf	2013-08-12T11:38:20Z				EC:5.6.1.5		molecular_function											owl:Class	
GO:2000623	biolink:NamedThing	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.	got7fsn_ti	negative regulation of nuclear mRNA catabolic process, nonsense-mediated decay|negative regulation of nonsense-mediated mRNA decay|negative regulation of mRNA catabolism, nonsense-mediated|negative regulation of mRNA breakdown, nonsense-mediated decay|negative regulation of mRNA degradation, nonsense-mediated decay|negative regulation of mRNA catabolic process, nonsense-mediated						pr	2011-04-18T03:32:46Z						biological_process											owl:Class	
GO:2000852	biolink:NamedThing	regulation of corticosterone secretion	Any process that modulates the frequency, rate or extent of corticosterone secretion.	got7fsn_ti							bf	2011-07-26T08:45:40Z						biological_process											owl:Class	
GO:1903040	biolink:NamedThing	exon-exon junction complex assembly	The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex.	got7fsn_ti	exon-exon junction complex formation|EJC formation|EJC assembly						sart	2014-05-20T14:52:07Z						biological_process											owl:Class	
GO:1905861	biolink:NamedThing	intranuclear rod assembly	The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod.	got7fsn_ti	intranuclear rod formation|intranuclear actin rod formation|intranuclear actin rod assembly						dph	2017-01-23T17:59:27Z						biological_process											owl:Class	
GO:2000540	biolink:NamedThing	negative regulation of protein geranylgeranylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation.	got7fsn_ti	negative regulation of C-terminal protein geranylgeranylation|negative regulation of protein amino acid geranylgeranylation						tb	2011-03-29T06:23:11Z						biological_process											owl:Class	
GO:2000215	biolink:NamedThing	negative regulation of proline metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process.	got7fsn_ti	negative regulation of proline metabolism						mah	2010-11-03T02:45:24Z						biological_process											owl:Class	
GO:1900749	biolink:NamedThing	(R)-carnitine transport	The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	Levocarnitine transport|Carnitene transport|(-)-Carnitine transport|(3R)-3-hydroxy-4-(trimethylammonio)butanoate transport|Carnitor transport|Carnicor transport|C7H15NO3 transport|Carnitine transport|(-)-L-Carnitine transport|Vitamin BT transport|L-Carnitine transport|(R)-Carnitine transport						jl	2012-05-29T02:01:17Z						biological_process											owl:Class	
GO:0009985	biolink:NamedThing	obsolete dihydroflavonol(thiole) lyase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dihydroflavonol(thiole) lyase activity				This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists.					True				molecular_function											owl:Class	
GO:2000737	biolink:NamedThing	negative regulation of stem cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.	got7fsn_ti							yaf	2011-06-14T02:05:20Z						biological_process											owl:Class	
GO:0051228	biolink:NamedThing	mitotic spindle disassembly	The controlled breakdown of the spindle during a mitotic cell cycle.	got7fsn_ti	spindle breakdown during mitosis|mitotic spindle degradation|spindle disassembly during mitosis|mitotic spindle catabolism|mitotic spindle breakdown|spindle degradation during mitosis													biological_process											owl:Class	
GO:0046234	biolink:NamedThing	obsolete fluorene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.	got7fsn_ti	fluorene anabolism|fluorene synthesis|fluorene biosynthetic process|fluorene biosynthesis|fluorene formation				This term was made obsolete because fluorene is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1903703	biolink:NamedThing	enterocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte.	got7fsn_ti							cls	2014-12-03T15:08:51Z						biological_process											owl:Class	
GO:0022629	biolink:NamedThing	chloroplast small ribosomal subunit	The small subunit of a ribosome contained within a chloroplast.	got7fsn_ti	chloroplast ribosomal SSU complex|chloroplast ribosomal small subunit complex													cellular_component											owl:Class	
GO:1902427	biolink:NamedThing	regulation of water channel activity	Any process that modulates the frequency, rate or extent of water channel activity.	got7fsn_ti	regulation of aquaporin|regulation of aquaporin permeability						bf	2013-09-23T12:56:31Z						biological_process											owl:Class	
GO:0001951	biolink:NamedThing	intestinal D-glucose absorption	Uptake of D-glucose into the blood by absorption from the small intestine.	got7fsn_ti														biological_process											owl:Class	
GO:1901899	biolink:NamedThing	positive regulation of relaxation of cardiac muscle	Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle.	got7fsn_ti	activation of relaxation of cardiac muscle|upregulation of relaxation of cardiac muscle|up regulation of relaxation of cardiac muscle|up-regulation of relaxation of cardiac muscle						rl	2013-02-06T21:27:07Z						biological_process											owl:Class	
GO:1990050	biolink:NamedThing	phosphatidic acid transfer activity	Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3.	got7fsn_ti	phosphatidic acid transporter activity|phosphatidic acid carrier activity|intermembrane PA transfer activity|intermembrane phosphatidic acid transfer activity						rb	2013-02-21T00:45:28Z						molecular_function											owl:Class	
GO:0099034	biolink:NamedThing	anchored component of postsynaptic endosome membrane	The component of the postsynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0099036	biolink:NamedThing	anchored component of neuronal dense core vesicle membrane	The component of the neuronal dense core vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:1904862	biolink:NamedThing	inhibitory synapse assembly	The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse.	got7fsn_ti	inhibitory synapse formation						bf	2015-12-17T10:31:34Z						biological_process											owl:Class	
CHEBI:47600	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990844	biolink:NamedThing	obsolete interfibrillar mitochondrion	OBSOLETE. A mitochondrion that occurs in between fibrils of striated muscle cells and responds in distinct ways to physiological triggers.	got7fsn_ti	IMF mitochondrion|intermyofibrillar mitochondrion|IFM				This term was obsoleted because it corresponds to mitochondria of specific cell types and this information should be captured as an extension.		sl	2015-08-31T16:26:44Z		True				cellular_component											owl:Class	
GO:1904730	biolink:NamedThing	negative regulation of intestinal lipid absorption	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption.	got7fsn_ti	down regulation of intestinal lipid absorption|down-regulation of intestinal lipid absorption|inhibition of intestinal lipid absorption|downregulation of intestinal lipid absorption						sl	2015-10-14T15:25:03Z						biological_process											owl:Class	
GO:0033805	biolink:NamedThing	obsolete sarcosine/dimethylglycine N-methyltransferase activity	OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine, and S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.	got7fsn_ti	S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity|sarcosine dimethylglycine N-methyltransferase activity|sarcosine/dimethylglycine N-methyltransferase activity|SDMT|sarcosine dimethylglycine methyltransferase activity|ApDMT				This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052729|GO:0052730				True				molecular_function											owl:Class	
GO:0010569	biolink:NamedThing	regulation of double-strand break repair via homologous recombination	Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.	got7fsn_ti														biological_process											owl:Class	
GO:1903977	biolink:NamedThing	positive regulation of glial cell migration	Any process that activates or increases the frequency, rate or extent of glial cell migration.	got7fsn_ti	activation of glial cell migration|up-regulation of glia cell migration|up regulation of glial cell migration|up regulation of glia cell migration|positive regulation of glia cell migration|activation of glia cell migration|upregulation of glia cell migration|up-regulation of glial cell migration|upregulation of glial cell migration						nc	2015-03-02T15:13:43Z						biological_process											owl:Class	
GO:1905290	biolink:NamedThing	negative regulation of CAMKK-AMPK signaling cascade	Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade.	got7fsn_ti	down-regulation of stress-activated AMP-activated protein kinase signaling cascade|down-regulation of CAMKK-AMPK signaling cascade|down regulation of CAMKK-AMPK signaling cascade|inhibition of stress-activated AMP-activated protein kinase signaling cascade|inhibition of CAMKK-AMPK signaling cascade|downregulation of stress-activated AMP-activated protein kinase signaling cascade|down regulation of stress-activated AMP-activated protein kinase signaling cascade|downregulation of CAMKK-AMPK signaling cascade|negative regulation of stress-activated AMP-activated protein kinase signaling cascade						sl	2016-06-23T20:37:03Z						biological_process											owl:Class	
GO:0031165	biolink:NamedThing	integral component of contractile vacuolar membrane	The component of the contractile vacuolar membrane consisting of gene products that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.	got7fsn_ti	integral to contractile vacuolar membrane													cellular_component											owl:Class	
GO:0039605	biolink:NamedThing	obsolete TFIIB-class transcription factor binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter	OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the TFIIB-class of host transcription factors, which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.	got7fsn_ti					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-07-05T04:16:45Z		True				molecular_function											owl:Class	
GO:0000311	biolink:NamedThing	plastid large ribosomal subunit	The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).	got7fsn_ti														cellular_component											owl:Class	
GO:0140284	biolink:NamedThing	endoplasmic reticulum-endosome membrane contact site	A contact site between the endoplasmic reticulum membrane and the endosome membrane.	got7fsn_ti	ER-endosome membrane contact site						pg	2018-10-30T10:29:28Z						cellular_component											owl:Class	
GO:0031407	biolink:NamedThing	oxylipin metabolic process	The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.	got7fsn_ti	oxylipin metabolism													biological_process											owl:Class	
GO:0032080	biolink:NamedThing	negative regulation of type I site-specific deoxyribonuclease activity	Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity.	got7fsn_ti	down-regulation of type I restriction endodeoxyribonuclease activity|type I restriction enzyme inhibitor|inhibition of type I restriction endodeoxyribonuclease activity|negative regulation of type I restriction endodeoxyribonuclease activity|type I restriction endodeoxyribonuclease inhibitor|downregulation of type I restriction endodeoxyribonuclease activity|down regulation of type I restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:1900944	biolink:NamedThing	regulation of isoprene metabolic process	Any process that modulates the frequency, rate or extent of isoprene metabolic process.	got7fsn_ti	regulation of hemiterpene metabolism|regulation of 2-methyl-1,3-butadiene metabolism|regulation of 2-methyl-1,3-butadiene metabolic process|regulation of hemiterpene metabolic process|regulation of isoprene metabolism						tt	2012-06-14T03:19:13Z						biological_process											owl:Class	
GO:0061925	biolink:NamedThing	negative regulation of formation of radial glial scaffolds	Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.	got7fsn_ti	negative regulation of Bergmann fiber biosynthesis|negative regulation of Bergmann fiber formation|negative regulation of radial glial scaffold formation						dph	2017-08-02T16:24:27Z						biological_process											owl:Class	
GO:0000195	biolink:NamedThing	obsolete nuclear translocation of MAPK (pseudohyphal growth)	OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth.	got7fsn_ti	nuclear translocation of MAPK (pseudohyphal growth)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:1900466	biolink:NamedThing	obsolete positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T07:38:14Z		True				biological_process											owl:Class	
UBERON:0005107	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150158	biolink:NamedThing	positive regulation of interleukin-34 production	Any process that activates or increases the frequency, rate or extent of interleukin-34 production.	got7fsn_ti	positive regulation of interleukin-34 biosynthetic process						bc	2020-01-06T16:31:00Z			GO:0150161			biological_process											owl:Class	
GO:0075705	biolink:NamedThing	obsolete viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane	OBSOLETE. The uptake of a virus into a host cell that begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicles containing the virus. The vesicle then delivers its viral content to early endosomes, and the process ends when the viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane.	got7fsn_ti	viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane|viral penetration via endocytosis followed by genetic injection through the endosome membrane				This term was made obsolete because it doesn't represent a genuine process. The term injection is mostly used for prokaryotic viruses where there is no endocytosis.		jl	2009-04-23T02:08:06Z		True				biological_process											owl:Class	
GO:0072708	biolink:NamedThing	response to sorbitol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.	got7fsn_ti	response to glucitol						mah	2012-04-11T03:40:57Z						biological_process											owl:Class	
GO:1901002	biolink:NamedThing	positive regulation of response to salt stress	Any process that activates or increases the frequency, rate or extent of response to salt stress.	got7fsn_ti	up regulation of response to salt stress|upregulation of response to salt stress|upregulation of salinity response|up regulation of response to ionic osmotic stress|upregulation of response to ionic osmotic stress|activation of salinity response|up regulation of salinity response|positive regulation of response to ionic osmotic stress|activation of response to ionic osmotic stress|positive regulation of salinity response|up-regulation of response to salt stress|up-regulation of salinity response|up-regulation of response to ionic osmotic stress|activation of response to salt stress						dhl	2012-06-14T05:41:50Z						biological_process											owl:Class	
GO:0017114	biolink:NamedThing	obsolete wide-spectrum protease inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of a protease by a wide-spectrum protease inhibitor. A wide-spectrum protease inhibitor is a protein having a peptide stretch which contains specific cleavage sites for different proteinases enabling inhibition of all four classes of proteinases by formation of a covalent bond between the inhibitor and the protease.	got7fsn_ti	wide-spectrum protease inhibitor activity|wide-spectrum proteinase inhibitor			GO:0030414	This term was made obsolete because it represents a regulator of non-existent molecular function.					True				molecular_function											owl:Class	
GO:0062085	biolink:NamedThing	positive regulation of capsule polysaccharide biosynthetic process	Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.	got7fsn_ti							dph	2018-10-31T16:02:00Z						biological_process											owl:Class	
GO:0046194	biolink:NamedThing	obsolete pentachlorophenol biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.	got7fsn_ti	pentachlorophenol synthesis|pentachlorophenol anabolism|pentachlorophenol formation|pentachlorophenol biosynthetic process|pentachlorophenol biosynthesis			GO:0018961	This term was made obsolete because pentachlorophenol is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1905689	biolink:NamedThing	positive regulation of diacylglycerol kinase activity	Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity.	got7fsn_ti	activation of DG kinase activity|up regulation of DG kinase activity|positive regulation of ATP:diacylglycerol phosphotransferase activity|positive regulation of DGK activity|positive regulation of DG kinase activity|upregulation of CTP:diacylglycerol kinase activity|upregulation of diglyceride kinase activity|upregulation of diacylglycerol:ATP kinase activity|activation of arachidonoyl-specific diacylglycerol kinase activity|activation of diacylglycerol kinase activity|up regulation of ATP:diacylglycerol phosphotransferase activity|activation of sn-1,2-diacylglycerol kinase activity|up regulation of diglyceride kinase activity|positive regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|activation of 1,2-diacylglycerol kinase (phosphorylating)|upregulation of sn-1,2-diacylglycerol kinase activity|positive regulation of 1,2-diacylglycerol kinase activity|up-regulation of diglyceride kinase activity|positive regulation of CTP:diacylglycerol kinase activity|up regulation of 1,2-diacylglycerol kinase (phosphorylating)|activation of 1,2-diacylglycerol kinase activity|up regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|positive regulation of diglyceride kinase activity|upregulation of DGK activity|positive regulation of diacylglycerol:ATP kinase activity|up-regulation of DG kinase activity|activation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|activation of CTP:diacylglycerol kinase activity|upregulation of diacylglycerol kinase activity|up-regulation of diacylglycerol:ATP kinase activity|up regulation of arachidonoyl-specific diacylglycerol kinase activity|up regulation of 1,2-diacylglycerol kinase activity|upregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|positive regulation of 1,2-diacylglycerol kinase (phosphorylating)|up-regulation of CTP:diacylglycerol kinase activity|up-regulation of arachidonoyl-specific diacylglycerol kinase activity|activation of diglyceride kinase activity|positive regulation of arachidonoyl-specific diacylglycerol kinase activity|activation of diacylglycerol:ATP kinase activity|up-regulation of 1,2-diacylglycerol kinase activity|up-regulation of ATP:diacylglycerol phosphotransferase activity|up regulation of sn-1,2-diacylglycerol kinase activity|up-regulation of diacylglycerol kinase activity|upregulation of 1,2-diacylglycerol kinase activity|activation of ATP:diacylglycerol phosphotransferase activity|up regulation of DGK activity|up regulation of diacylglycerol kinase activity|up-regulation of DGK activity|activation of DGK activity|upregulation of arachidonoyl-specific diacylglycerol kinase activity|up-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up-regulation of sn-1,2-diacylglycerol kinase activity|upregulation of 1,2-diacylglycerol kinase (phosphorylating)|upregulation of DG kinase activity|up regulation of CTP:diacylglycerol kinase activity|upregulation of ATP:diacylglycerol phosphotransferase activity|up regulation of diacylglycerol:ATP kinase activity|up-regulation of 1,2-diacylglycerol kinase (phosphorylating)|positive regulation of sn-1,2-diacylglycerol kinase activity						bc	2016-11-14T12:26:26Z						biological_process											owl:Class	
GO:0090085	biolink:NamedThing	regulation of protein deubiquitination	Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.	got7fsn_ti							tb	2009-10-23T11:16:32Z						biological_process											owl:Class	
GO:0060382	biolink:NamedThing	regulation of DNA strand elongation	Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.	got7fsn_ti														biological_process											owl:Class	
GO:1904816	biolink:NamedThing	positive regulation of protein localization to chromosome, telomeric region	Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region.	got7fsn_ti	activation of protein localization to telomere|activation of protein localisation to chromosome, telomeric region|positive regulation of protein localization to telomere|up regulation of protein localisation to chromosome, telomeric region|activation of protein localization to chromosome, telomeric region|up regulation of protein localization to telomere|upregulation of protein localisation to chromosome, telomeric region|up-regulation of protein localization to chromosome, telomeric region|up-regulation of protein localization to telomere|positive regulation of protein localisation to chromosome, telomeric region|up regulation of protein localization to chromosome, telomeric region|upregulation of protein localization to chromosome, telomeric region|upregulation of protein localization to telomere|up-regulation of protein localisation to chromosome, telomeric region						nc	2015-11-16T12:18:58Z						biological_process											owl:Class	
GO:1905868	biolink:NamedThing	regulation of 3'-UTR-mediated mRNA stabilization	Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.	got7fsn_ti	regulation of 3'-untranslated region-mediated mRNA stabilization						rz	2017-01-27T11:51:37Z						biological_process											owl:Class	
GO:0003820	biolink:NamedThing	obsolete class I major histocompatibility complex antigen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	class I major histocompatibility complex antigen				This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.	GO:0042612				True				molecular_function											owl:Class	
GO:0002091	biolink:NamedThing	negative regulation of receptor internalization	Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.	got7fsn_ti	downregulation of receptor internalization|down regulation of receptor internalization|down-regulation of receptor internalization|inhibition of receptor internalization													biological_process											owl:Class	
GO:0008430	biolink:NamedThing	selenium binding	Binding to a selenium (Se) ion.	got7fsn_ti														molecular_function											owl:Class	
GO:1902604	biolink:NamedThing	p-aminobenzoyl-glutamate transmembrane transport	The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane.	got7fsn_ti	N-(4-aminobenzoyl)-L-glutamate transmembrane transport						pr	2013-12-20T11:09:20Z						biological_process											owl:Class	
GO:0051929	biolink:NamedThing	obsolete positive regulation of calcium ion transport via voltage-gated calcium channel activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via the activity of voltage-gated calcium channels.	got7fsn_ti	positive regulation of calcium ion transport via voltage-gated calcium channel activity|stimulation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium transport via voltage gated calcium channel|activation of calcium ion transport via voltage gated calcium channel|up-regulation of calcium ion transport via voltage gated calcium channel|up regulation of calcium ion transport via voltage gated calcium channel|upregulation of calcium ion transport via voltage gated calcium channel				This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0005245				True				biological_process											owl:Class	
GO:1900034	biolink:NamedThing	regulation of cellular response to heat	Any process that modulates the frequency, rate or extent of cellular response to heat.	got7fsn_ti	regulation of cellular response to heat stress						yaf	2012-01-17T09:27:40Z						biological_process											owl:Class	
GO:0120093	biolink:NamedThing	regulation of peptidyl-lysine crotonylation	Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein.	got7fsn_ti							krc	2017-08-22T20:25:51Z						biological_process											owl:Class	
GO:0032756	biolink:NamedThing	positive regulation of interleukin-7 production	Any process that activates or increases the frequency, rate, or extent of interleukin-7 production.	got7fsn_ti	stimulation of interleukin-7 production|positive regulation of IL-7 production|activation of interleukin-7 production|up-regulation of interleukin-7 production|upregulation of interleukin-7 production|positive regulation of interleukin-7 secretion|up regulation of interleukin-7 production|positive regulation of interleukin-7 biosynthetic process										GO:0150114|GO:0045413			biological_process											owl:Class	
UBERON:0002405	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051465	biolink:NamedThing	negative regulation of corticotropin-releasing hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.	got7fsn_ti	negative regulation of CRH secretion|downregulation of corticotropin-releasing hormone secretion|negative regulation of CRF secretion|down regulation of corticotropin-releasing hormone secretion|down-regulation of corticotropin-releasing hormone secretion|negative regulation of corticotropin-releasing factor secretion|inhibition of corticotropin-releasing hormone secretion													biological_process											owl:Class	
GO:0046361	biolink:NamedThing	2-oxobutyrate metabolic process	The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.	got7fsn_ti	alpha-ketobutyrate metabolic process|alpha-ketobutyrate metabolism|2-oxobutyrate metabolism													biological_process											owl:Class	
GO:1900385	biolink:NamedThing	negative regulation of flavonol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process.	got7fsn_ti	inhibition of flavonol biosynthetic process|down-regulation of flavonol biosynthetic process|downregulation of flavonol biosynthetic process|down regulation of flavonol biosynthetic process						tb	2012-04-17T10:22:59Z						biological_process											owl:Class	
GO:0032693	biolink:NamedThing	negative regulation of interleukin-10 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.	got7fsn_ti	downregulation of interleukin-10 production|inhibition of interleukin-10 production|negative regulation of interleukin-10 biosynthetic process|negative regulation of interleukin-10 secretion|down-regulation of interleukin-10 production|down regulation of interleukin-10 production|negative regulation of IL-10 production										GO:0045081|GO:2001180			biological_process											owl:Class	
CHEBI:59908	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052440	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:2000303	biolink:NamedThing	regulation of ceramide biosynthetic process	Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.	got7fsn_ti	regulation of ceramide formation|regulation of ceramide anabolism|regulation of ceramide synthesis|regulation of ceramide biosynthesis						dph	2011-01-04T02:37:12Z						biological_process											owl:Class	
GO:0032017	biolink:NamedThing	positive regulation of Ran protein signal transduction	Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction.	got7fsn_ti	stimulation of Ran protein signal transduction|up regulation of Ran protein signal transduction|activation of Ran protein signal transduction|up-regulation of Ran protein signal transduction|upregulation of Ran protein signal transduction													biological_process											owl:Class	
GO:0002231	biolink:NamedThing	detection of oomycetes	The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal.	got7fsn_ti														biological_process											owl:Class	
GO:0010831	biolink:NamedThing	positive regulation of myotube differentiation	Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	got7fsn_ti														biological_process											owl:Class	
GO:1900066	biolink:NamedThing	positive regulation of ethanol catabolic process	Any process that activates or increases the frequency, rate or extent of ethanol catabolic process.	got7fsn_ti	activation of ethanol degradation|upregulation of ethanol catabolism|activation of ethanol breakdown|positive regulation of ethanol degradation|positive regulation of ethanol catabolism|up-regulation of ethanol catabolism|up-regulation of ethanol breakdown|up regulation of ethanol catabolism|up-regulation of ethanol catabolic process|upregulation of ethanol degradation|upregulation of ethanol breakdown|up regulation of ethanol degradation|up-regulation of ethanol degradation|activation of ethanol catabolism|upregulation of ethanol catabolic process|activation of ethanol catabolic process|up regulation of ethanol breakdown|up regulation of ethanol catabolic process|positive regulation of ethanol breakdown						dph	2012-01-26T01:51:44Z						biological_process											owl:Class	
GO:1900954	biolink:NamedThing	negative regulation of 18-methylnonadec-1-ene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.	got7fsn_ti	down regulation of 18-methylnonadec-1-ene metabolism|down-regulation of 18-methylnonadec-1-ene metabolism|inhibition of 18-methylnonadec-1-ene metabolism|down regulation of 18-methylnonadec-1-ene metabolic process|downregulation of 18-methylnonadec-1-ene metabolism|inhibition of 18-methylnonadec-1-ene metabolic process|downregulation of 18-methylnonadec-1-ene metabolic process|down-regulation of 18-methylnonadec-1-ene metabolic process|negative regulation of 18-methylnonadec-1-ene metabolism						tt	2012-06-14T03:25:37Z						biological_process											owl:Class	
GO:1903538	biolink:NamedThing	regulation of meiotic cell cycle process involved in oocyte maturation	Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.	got7fsn_ti	regulation of meiosis involved in oocyte maturation						pr	2014-10-09T10:52:38Z						biological_process											owl:Class	
GO:0071270	biolink:NamedThing	1-butanol metabolic process	The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O.	got7fsn_ti	butan-1-ol metabolic process|butanol metabolic process|1-butanol metabolism						mah	2009-12-10T10:23:11Z						biological_process											owl:Class	
GO:0052321	biolink:NamedThing	negative regulation of phytoalexin metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.	got7fsn_ti	down regulation of phytoalexin metabolism|negative regulation of phytoalexin metabolism|inhibition of phytoalexin metabolism|downregulation of phytoalexin metabolism|down-regulation of phytoalexin metabolism													biological_process											owl:Class	
GO:0060979	biolink:NamedThing	vasculogenesis involved in coronary vascular morphogenesis	The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.	got7fsn_ti	vasculogenesis involved in coronary blood vessel morphogenesis|coronary vasculogenesis						dph	2009-10-06T02:19:42Z						biological_process											owl:Class	
GO:1900543	biolink:NamedThing	negative regulation of purine nucleotide metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.	got7fsn_ti	inhibition of purine metabolic process|down-regulation of purine metabolism|downregulation of purine nucleotide metabolism|inhibition of purine metabolism|inhibition of purine nucleotide metabolism|downregulation of purine metabolism|downregulation of purine metabolic process|down regulation of purine nucleotide metabolism|down regulation of purine nucleotide metabolic process|negative regulation of purine metabolic process|downregulation of purine nucleotide metabolic process|negative regulation of purine metabolism|down regulation of purine metabolic process|inhibition of purine nucleotide metabolic process|negative regulation of purine nucleotide metabolism|down regulation of purine metabolism|down-regulation of purine nucleotide metabolic process|down-regulation of purine metabolic process|down-regulation of purine nucleotide metabolism						krc	2012-05-11T05:44:21Z						biological_process											owl:Class	
GO:0070623	biolink:NamedThing	regulation of thiamine biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.	got7fsn_ti	regulation of thiamine anabolism|regulation of thiamin biosynthetic process|regulation of thiamine synthesis|regulation of thiamine biosynthesis|regulation of thiamine formation						mah	2009-05-01T03:15:49Z						biological_process											owl:Class	
GO:0071230	biolink:NamedThing	cellular response to amino acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.	got7fsn_ti	cellular response to amino acid						mah	2009-12-03T02:08:11Z						biological_process											owl:Class	
GO:1903608	biolink:NamedThing	protein localization to cytoplasmic stress granule	A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule.	got7fsn_ti	protein localization in cytoplasmic stress granule|protein localization to stress granule|protein localisation in cytoplasmic stress granule|protein localisation to cytoplasmic stress granule						mah	2014-11-14T16:20:32Z						biological_process											owl:Class	
GO:0009806	biolink:NamedThing	lignan metabolic process	The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.	got7fsn_ti	lignan metabolism													biological_process											owl:Class	
GO:0070810	biolink:NamedThing	positive regulation of Hulle cell development	Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.	got7fsn_ti							mah	2009-07-08T04:54:12Z						biological_process											owl:Class	
GO:0045642	biolink:NamedThing	positive regulation of basophil differentiation	Any process that activates or increases the frequency, rate or extent of basophil differentiation.	got7fsn_ti	up-regulation of basophil differentiation|activation of basophil differentiation|up regulation of basophil differentiation|upregulation of basophil differentiation|stimulation of basophil differentiation													biological_process											owl:Class	
GO:1903890	biolink:NamedThing	positive regulation of plant epidermal cell differentiation	Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation.	got7fsn_ti	upregulation of plant epidermal cell differentiation|up-regulation of plant epidermal cell differentiation|activation of plant epidermal cell differentiation|up regulation of plant epidermal cell differentiation						tb	2015-02-06T22:30:02Z						biological_process											owl:Class	
GO:0010870	biolink:NamedThing	obsolete positive regulation of receptor biosynthetic process	OBSOLETE. Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1904978	biolink:NamedThing	regulation of endosome organization	Any process that modulates the frequency, rate or extent of endosome organization.	got7fsn_ti	regulation of endosome organization and biogenesis|regulation of endosome organisation						pad	2016-02-22T19:21:01Z						biological_process											owl:Class	
GO:0090286	biolink:NamedThing	obsolete cytoskeletal anchoring at nuclear membrane	OBSOLETE. The process in which cytoskeletal filaments are directly or indirectly linked to the nuclear membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18283			This term was obsoleted because it represented a molecular function.	GO:0140444	tb	2010-02-18T02:56:26Z		True				biological_process											owl:Class	
GO:0045678	biolink:NamedThing	positive regulation of R7 cell differentiation	Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.	got7fsn_ti	up-regulation of R7 differentiation|activation of R7 differentiation|positive regulation of R7 differentiation|stimulation of R7 differentiation|upregulation of R7 differentiation|up regulation of R7 differentiation													biological_process											owl:Class	
GO:2000502	biolink:NamedThing	negative regulation of natural killer cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis.	got7fsn_ti							bf	2011-03-21T10:09:32Z						biological_process											owl:Class	
GO:0150110	biolink:NamedThing	negative regulation of cholesterol esterification	Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol esterification.	got7fsn_ti							bc	2019-07-23T15:34:42Z						biological_process											owl:Class	
GO:1900858	biolink:NamedThing	regulation of brevianamide F biosynthetic process	Any process that modulates the frequency, rate or extent of brevianamide F biosynthetic process.	got7fsn_ti	regulation of brevianamide F biosynthesis|regulation of brevianamide F synthesis|regulation of brevianamide F formation|regulation of brevianamide F anabolism						di	2012-06-07T09:52:56Z						biological_process											owl:Class	
GO:2000895	biolink:NamedThing	hemicellulose catabolic process	The chemical reactions and pathways resulting in the breakdown of a hemicellulose.	got7fsn_ti	hemicellulose catabolism						jl	2011-07-28T02:08:11Z						biological_process											owl:Class	
GO:0010634	biolink:NamedThing	positive regulation of epithelial cell migration	Any process that activates or increases the frequency, rate or extent of epithelial cell migration.	got7fsn_ti														biological_process											owl:Class	
GO:1903212	biolink:NamedThing	protein localization to mating-type region heterochromatin	A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin.	got7fsn_ti	protein localisation to mating-type region heterochromatin|protein localisation in mating-type region heterochromatin|protein localization in mating-type region heterochromatin						mah	2014-07-24T09:38:12Z						biological_process											owl:Class	
GO:0042080	biolink:NamedThing	obsolete GPI/GSI anchor biosynthetic process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	GPI/GSI anchor biosynthesis|GPI/GSI anchor biosynthetic process|GPI/GSI anchor synthesis|GPI/GSI anchor anabolism|GPI/GSI anchor formation				This term was made obsolete because it is a composite term that represents two individual processes.	GO:0006506|GO:0042082				True				biological_process											owl:Class	
GO:1902433	biolink:NamedThing	positive regulation of water channel activity involved in maintenance of lens transparency	Any positive regulation of water channel activity that is involved in maintenance of lens transparency.	got7fsn_ti	aquaporin activation involved in maintenance of ocular lens transparency|activation of aquaporin involved in maintenance of ocular lens transparency|up regulation of water channel activity involved in preservation of lens transparency|up regulation of aquaporin involved in maintenance of lens transparency|positive regulation of aquaporin involved in preservation of lens transparency|aquaporin activation involved in maintenance of lens transparency|up-regulation of aquaporin involved in maintenance of lens transparency|positive regulation of water channel activity involved in maintenance of ocular lens transparency|activation of water channel activity involved in preservation of lens transparency|up-regulation of water channel activity involved in preservation of lens transparency|positive regulation of aquaporin involved in maintenance of ocular lens transparency|upregulation of water channel activity involved in maintenance of ocular lens transparency|up regulation of aquaporin involved in preservation of lens transparency|activation of aquaporin involved in preservation of lens transparency|up-regulation of water channel activity involved in maintenance of lens transparency|activation of aquaporin involved in maintenance of lens transparency|activation of water channel activity involved in maintenance of ocular lens transparency|upregulation of aquaporin involved in maintenance of ocular lens transparency|up-regulation of aquaporin involved in maintenance of ocular lens transparency|upregulation of aquaporin involved in preservation of lens transparency|upregulation of water channel activity involved in preservation of lens transparency|positive regulation of aquaporin involved in maintenance of lens transparency|aquaporin activation involved in preservation of lens transparency|upregulation of aquaporin involved in maintenance of lens transparency|up regulation of water channel activity involved in maintenance of ocular lens transparency|activation of water channel activity involved in maintenance of lens transparency|upregulation of water channel activity involved in maintenance of lens transparency|positive regulation of water channel activity involved in preservation of lens transparency|up regulation of aquaporin involved in maintenance of ocular lens transparency|up-regulation of aquaporin involved in preservation of lens transparency|up-regulation of water channel activity involved in maintenance of ocular lens transparency|up regulation of water channel activity involved in maintenance of lens transparency						bf	2013-10-02T12:58:00Z						biological_process											owl:Class	
GO:1905882	biolink:NamedThing	obsolete other organism cell wall	OBSOLETE. Any cell wall that is part of a other organism.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		pga	2017-01-31T10:57:28Z		True				cellular_component											owl:Class	
GO:0031450	biolink:NamedThing	negative regulation of slow-twitch skeletal muscle fiber contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction.	got7fsn_ti	downregulation of slow-twitch skeletal muscle contraction|down regulation of slow-twitch skeletal muscle contraction|down-regulation of slow-twitch skeletal muscle contraction|negative regulation of slow-twitch skeletal muscle contraction|inhibition of slow-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:0048033	biolink:NamedThing	heme o metabolic process	The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.	got7fsn_ti	haem o metabolism|haem o metabolic process|heme o metabolism													biological_process											owl:Class	
GO:0008220	biolink:NamedThing	obsolete necrosis	OBSOLETE. The processes that cause necrosis, the death of tissues, in another organism.	got7fsn_ti	necrosis				This term was made obsolete because the term has been used in the literature by groups in different areas of biology with a number of varying explicit and implicit definitions, and more appropriate terms were created.	GO:0070265|GO:0008219|GO:0012501|GO:0019835|GO:0001906				True				biological_process											owl:Class	
GO:0004263	biolink:NamedThing	obsolete chymotrypsin activity	OBSOLETE. Catalysis of the preferential cleavage of Tyr-Xaa > Trp-Xaa > Phe-Xaa > Leu-Xaa.	got7fsn_ti	alpha-chymar|quimotrase activity|alpha-chymotrypsin activity|alpha-chymar ophth|chymotrypsin A activity|chymar|chymotrypsin activity|alpha-chymotrypsin A|enzeon|avazyme|chymotest|chymotrypsin B activity|chymotrypsins A and B|quimar			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0070863	biolink:NamedThing	positive regulation of protein exit from endoplasmic reticulum	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.	got7fsn_ti	upregulation of protein exit from endoplasmic reticulum|up-regulation of protein exit from endoplasmic reticulum|stimulation of protein exit from endoplasmic reticulum|positive regulation of protein exit from ER|positive regulation of protein export from ER|activation of protein exit from endoplasmic reticulum|positive regulation of protein export from endoplasmic reticulum|up regulation of protein exit from endoplasmic reticulum						mah	2009-08-17T03:50:04Z						biological_process											owl:Class	
GO:0140351	biolink:NamedThing	glycosylceramide flippase activity	Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar.	got7fsn_ti	glycosylceramide flippase activity (exoplasmic to cytosolic leaftlet)|galactosylceramide flippase activity|galactocerebroside flippase activity|glucosylceramide flippase activity|glycoceramide flippase activity						pg	2019-05-20T13:29:48Z						molecular_function											owl:Class	
GO:1905270	biolink:NamedThing	Meynert cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell.	got7fsn_ti							cjm	2016-06-15T23:44:17Z						biological_process											owl:Class	
GO:0150175	biolink:NamedThing	regulation of phosphatidylethanolamine metabolic process	Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process.	got7fsn_ti							bc	2020-01-21T14:04:12Z						biological_process											owl:Class	
CHEBI:25197	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044679	biolink:NamedThing	methanophenazine reducing hydrogenase complex	A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides.	got7fsn_ti							jl	2012-08-09T11:07:20Z						cellular_component											owl:Class	
GO:0099613	biolink:NamedThing	protein localization to cell wall	The process of directing proteins towards the cell-wall.	got7fsn_ti														biological_process											owl:Class	
GO:0035415	biolink:NamedThing	obsolete regulation of mitotic prometaphase	OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.	got7fsn_ti	regulation of mitotic prometaphase				This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		bf	2010-03-29T10:52:08Z		True				biological_process											owl:Class	
GO:1904419	biolink:NamedThing	negative regulation of telomeric loop formation	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation.	got7fsn_ti	downregulation of t-loop biosynthesis|down-regulation of t-loop biosynthesis|down regulation of t-loop formation|inhibition of t-loop biosynthesis|negative regulation of t-loop biosynthesis|negative regulation of t-loop formation|down regulation of telomeric loop formation|downregulation of t-loop formation|downregulation of telomeric loop formation|down regulation of t-loop biosynthesis|down-regulation of telomeric loop formation|inhibition of t-loop formation|inhibition of telomeric loop formation|down-regulation of t-loop formation						nc	2015-07-01T10:40:29Z						biological_process											owl:Class	
GO:0060768	biolink:NamedThing	regulation of epithelial cell proliferation involved in prostate gland development	Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.	got7fsn_ti							dph	2009-07-08T07:34:56Z						biological_process											owl:Class	
UBERON:0001013	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901661	biolink:NamedThing	quinone metabolic process	The chemical reactions and pathways involving quinone.	got7fsn_ti	quinone cofactor metabolic process|quinone metabolism|quinone cofactor metabolism						pr	2012-11-20T14:44:39Z			GO:0042375			biological_process											owl:Class	
GO:1901837	biolink:NamedThing	negative regulation of transcription of nucleolar large rRNA by RNA polymerase I	Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I.	got7fsn_ti	downregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|down-regulation of transcription of nuclear rRNA large Pol I transcript|negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|down regulation of transcription of nuclear rRNA large Pol I transcript|down-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|downregulation of transcription of nuclear rRNA large Pol I transcript|inhibition of transcription of nuclear rRNA large Pol I transcript|negative regulation of transcription of nuclear rRNA large Pol I transcript|inhibition of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|down regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter						sart	2013-01-23T10:16:31Z						biological_process											owl:Class	
GO:2000427	biolink:NamedThing	positive regulation of apoptotic cell clearance	Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance.	got7fsn_ti	positive regulation of apoptotic cell removal|positive regulation of programmed cell clearance|positive regulation of efferocytosis						bf	2011-02-25T11:50:59Z						biological_process											owl:Class	
GO:2000751	biolink:NamedThing	histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore	Any histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore.	got7fsn_ti	histone H3-T3 phosphorylation of CPC localization to kinetochore|histone H3-T3 phosphorylation of CPC complex localization to kinetochore|histone H3-T3 phosphorylation of chromosome passenger complex localisation to kinetochore|histone H3-T3 phosphorylation of chromosome passenger complex localization to kinetochore|histone H3-T3 phosphorylation of chromosomal passenger complex localization to kinetochore						vw	2011-06-16T12:56:29Z						biological_process											owl:Class	
GO:0042027	biolink:NamedThing	obsolete cyclophilin-type peptidyl-prolyl cis-trans isomerase activity	OBSOLETE. Catalysis of the reaction: peptidylproline (omega=180) = peptidylproline (omega=0).	got7fsn_ti	cyclophilin-type peptidyl-prolyl cis-trans isomerase activity				This term was made obsolete because it is contains gene product specific characteristics.	GO:0003755				True				molecular_function											owl:Class	
GO:1904212	biolink:NamedThing	regulation of iodide transmembrane transport	Any process that modulates the frequency, rate or extent of iodide transmembrane transport.	got7fsn_ti							sl	2015-05-14T19:00:02Z						biological_process											owl:Class	
CHEBI:24148	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034316	biolink:NamedThing	negative regulation of Arp2/3 complex-mediated actin nucleation	Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.	got7fsn_ti														biological_process											owl:Class	
CHEBI:27899	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905633	biolink:NamedThing	establishment of protein localization to euchromatin	The directed movement of a protein to a specific location in an euchromatin.	got7fsn_ti	establishment of protein localisation to euchromatin|establishment of protein localization in euchromatin|establishment of protein localisation in euchromatin						pga	2016-11-01T16:16:22Z						biological_process											owl:Class	
UBERON:0001293	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905411	biolink:NamedThing	positive regulation of mitotic cohesin unloading	Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading.	got7fsn_ti							vw	2016-08-25T15:45:30Z						biological_process											owl:Class	
GO:0021909	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord anterior-posterior patterning	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0021512				True				biological_process											owl:Class	
GO:1902617	biolink:NamedThing	response to fluoride	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.	got7fsn_ti							kmv	2014-01-10T19:41:49Z						biological_process											owl:Class	
GO:1905310	biolink:NamedThing	regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.	got7fsn_ti							rl	2016-07-11T17:34:26Z						biological_process											owl:Class	
GO:0045800	biolink:NamedThing	negative regulation of chitin-based cuticle tanning	Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning.	got7fsn_ti	downregulation of cuticle tanning|down regulation of cuticle tanning|negative regulation of cuticle hardening|negative regulation of cuticle tanning|down-regulation of cuticle tanning|inhibition of cuticle tanning													biological_process											owl:Class	
GO:0006512	biolink:NamedThing	obsolete ubiquitin cycle	OBSOLETE. The cyclical process by which one or more ubiquitin groups are added to (ubiquitination) and removed from (deubiquitination) a protein.	got7fsn_ti	ubiquitin cycle				This term was made obsolete because it implies that every protein that is ubiquitinated is also subsequently deubiquinitated, which is not true. Also, the process ontology does not include analogous terms for other small modifiers.					True				biological_process											owl:Class	
GO:0023048	biolink:NamedThing	obsolete signal initiation by lipid mediator	OBSOLETE. The process in which a lipid signal causes activation of a receptor.	got7fsn_ti	signal initiation by lipid mediator				This term was made obsolete because the meaning of the term is ambiguous.	GO:0045125|GO:0007165		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0001408	biolink:NamedThing	guanine nucleotide transport	The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1903014	biolink:NamedThing	cellular response to differentiation-inducing factor 1	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.	got7fsn_ti	DIF-1|cellular response to DIF-1|cellular response to DIF1|cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one						rjd	2014-05-14T16:18:18Z						biological_process											owl:Class	
GO:1900309	biolink:NamedThing	regulation of maltoheptaose metabolic process	Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process.	got7fsn_ti	regulation of maltoheptaose metabolism						tt	2012-04-05T07:58:48Z						biological_process											owl:Class	
GO:0014040	biolink:NamedThing	positive regulation of Schwann cell differentiation	Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.	got7fsn_ti	upregulation of Schwann cell differentiation|activation of Schwann cell differentiation|up-regulation of Schwann cell differentiation|stimulation of Schwann cell differentiation|up regulation of Schwann cell differentiation													biological_process											owl:Class	
GO:0050656	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate binding	Binding to 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.	got7fsn_ti	phosphoadenosine phosphosulfate binding|3'-phosphoadenosine 5'-phosphosulphate binding|3'-phosphoadenylyl-sulfate binding|PAPS binding|adenosine 3'-phosphate 5'-phosphosulfate binding													molecular_function											owl:Class	
CL:2000038	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099517	biolink:NamedThing	synaptic vesicle transport along microtubule	The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors.	got7fsn_ti														biological_process											owl:Class	
GO:0015061	biolink:NamedThing	obsolete red-sensitive opsin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	red-sensitive opsin				This term was made obsolete because it refers to a class of proteins.	GO:0046876|GO:0007603|GO:0016918|GO:0016021|GO:0009585|GO:0009881				True				molecular_function											owl:Class	
GO:0015817	biolink:NamedThing	histidine transport	The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-histidine transport													biological_process											owl:Class	
GO:0016733	biolink:NamedThing	obsolete iron-iron nitrogenase activity	OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.	got7fsn_ti	iron-iron nitrogenase activity				This term was made obsolete because it represents a cellular component.	GO:0016611|GO:0016163				True				molecular_function											owl:Class	
GO:1902638	biolink:NamedThing	neural crest cell differentiation involved in parathyroid gland development	Any neural crest cell differentiation that is involved in parathyroid gland development.	got7fsn_ti							pr	2014-01-21T10:03:29Z						biological_process											owl:Class	
GO:0071240	biolink:NamedThing	cellular response to food	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.	got7fsn_ti							mah	2009-12-03T02:28:35Z						biological_process											owl:Class	
CHEBI:28057	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905267	biolink:NamedThing	endonucleolytic cleavage involved in tRNA processing	Any endonucleolytic RNA phosphodiester bond hydrolysis that is involved in tRNA processing.	got7fsn_ti	RNA phosphodiester bond hydrolysis, endonucleolytic involved in tRNA maturation						al	2016-06-14T14:54:54Z						biological_process											owl:Class	
GO:0008351	biolink:NamedThing	obsolete microtubule severing activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	microtubule severing activity				This term was made obsolete because it describes a biological process.	GO:0051013|GO:0008017				True				molecular_function											owl:Class	
GO:1905537	biolink:NamedThing	positive regulation of eukaryotic translation initiation factor 4F complex assembly	Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.	got7fsn_ti	activation of eIF-4F assembly|upregulation of eIF-4F assembly|upregulation of eukaryotic translation initiation factor 4F complex assembly|activation of eIF4F assembly|upregulation of eIF4F assembly|up regulation of eIF4F assembly|up regulation of eIF-4F assembly|up-regulation of eIF-4F assembly|up-regulation of eukaryotic translation initiation factor 4F complex assembly|up-regulation of eIF4F assembly|activation of eukaryotic translation initiation factor 4F complex assembly|positive regulation of eIF4F assembly|positive regulation of eIF-4F assembly|up regulation of eukaryotic translation initiation factor 4F complex assembly						bc	2016-10-06T14:05:13Z						biological_process											owl:Class	
GO:1901316	biolink:NamedThing	positive regulation of histone H2A K63-linked ubiquitination	Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination.	got7fsn_ti	up regulation of histone H2A K63-linked ubiquitination|upregulation of histone H2A K63-linked ubiquitination|activation of histone H2A K63-linked ubiquitination|up-regulation of histone H2A K63-linked ubiquitination						tb	2012-08-22T20:29:32Z						biological_process											owl:Class	
GO:0045767	biolink:NamedThing	obsolete regulation of anti-apoptosis	OBSOLETE. Any process that modulates the frequency, rate or extent of anti-apoptosis.	got7fsn_ti	regulation of anti-apoptosis				This term was made obsolete because it was ill-defined.					True				biological_process											owl:Class	
GO:2000182	biolink:NamedThing	regulation of progesterone biosynthetic process	Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.	got7fsn_ti	regulation of progesterone synthesis|regulation of progesterone formation|regulation of progesterone biosynthesis|regulation of progesterone anabolism						dph	2010-10-14T07:36:06Z						biological_process											owl:Class	
GO:0032953	biolink:NamedThing	regulation of (1->3)-beta-D-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.	got7fsn_ti	regulation of 1,3-beta-glucan biosynthetic process|regulation of 1,3-beta-glucan anabolism|regulation of 1,3-beta-glucan synthesis|regulation of 1,3-beta-glucan formation|regulation of 1,3-beta-glucan biosynthesis													biological_process											owl:Class	
GO:0033603	biolink:NamedThing	positive regulation of dopamine secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.	got7fsn_ti	activation of dopamine secretion|upregulation of dopamine secretion|up-regulation of dopamine secretion|stimulation of dopamine secretion|up regulation of dopamine secretion													biological_process											owl:Class	
GO:1901047	biolink:NamedThing	insulin receptor signaling pathway involved in determination of adult lifespan	The series of molecular signals generated as a consequence of the insulin receptor binding to insulin that controls viability and duration in the adult phase of the life-cycle.	got7fsn_ti	insulin receptor signalling pathway of determination of adult lifespan|insulin receptor signaling pathway of determination of adult lifespan|daf-2 receptor signaling pathway of determination of adult lifespan						kmv	2012-06-27T06:55:18Z						biological_process											owl:Class	
SO:0001798	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905225	biolink:NamedThing	response to thyrotropin-releasing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.	got7fsn_ti	response to TRH|response to protirelin						pr	2016-06-07T12:11:28Z						biological_process											owl:Class	
GO:0010269	biolink:NamedThing	response to selenium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.	got7fsn_ti														biological_process											owl:Class	
GO:2001098	biolink:NamedThing	tetrasaccharide transport	The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:12:53Z						biological_process											owl:Class	
GO:0075101	biolink:NamedThing	obsolete negative regulation by host of symbiont protein kinase-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
CL:1001611	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140125	biolink:NamedThing	thiamine import across plasma membrane	The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2017-10-25T11:09:23Z						biological_process											owl:Class	
GO:0061352	biolink:NamedThing	cell chemotaxis involved in Malpighian tubule morphogenesis	The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.	got7fsn_ti							dph	2010-10-01T11:57:28Z						biological_process											owl:Class	
GO:1900668	biolink:NamedThing	negative regulation of endocrocin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process.	got7fsn_ti	negative regulation of endocrocin anabolism|down regulation of endocrocin synthesis|negative regulation of endocrocin formation|down regulation of endocrocin formation|downregulation of endocrocin synthesis|down-regulation of endocrocin formation|inhibition of endocrocin biosynthesis|down-regulation of endocrocin biosynthetic process|negative regulation of endocrocin synthesis|down-regulation of endocrocin biosynthesis|down-regulation of endocrocin anabolism|inhibition of endocrocin biosynthetic process|downregulation of endocrocin formation|downregulation of endocrocin anabolism|downregulation of endocrocin biosynthesis|down regulation of endocrocin anabolism|down regulation of endocrocin biosynthesis|down-regulation of endocrocin synthesis|inhibition of endocrocin anabolism|down regulation of endocrocin biosynthetic process|negative regulation of endocrocin biosynthesis|inhibition of endocrocin synthesis|downregulation of endocrocin biosynthetic process|inhibition of endocrocin formation						di	2012-05-22T04:16:25Z						biological_process											owl:Class	
UBERON:0006696	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901257	biolink:NamedThing	negative regulation of macrophage colony-stimulating factor production	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production.	got7fsn_ti	downregulation of macrophage colony-stimulating factor production|down regulation of macrophage colony-stimulating factor production|downregulation of M-CSF production|negative regulation of M-CSF production|inhibition of M-CSF production|down-regulation of macrophage colony-stimulating factor production|down-regulation of M-CSF production|inhibition of macrophage colony-stimulating factor production|down regulation of M-CSF production						vk	2012-08-10T08:28:28Z						biological_process											owl:Class	
GO:1903937	biolink:NamedThing	response to acrylamide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.	got7fsn_ti							sl	2015-02-12T22:00:24Z						biological_process											owl:Class	
GO:0051466	biolink:NamedThing	positive regulation of corticotropin-releasing hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.	got7fsn_ti	positive regulation of CRH secretion|positive regulation of CRF secretion|upregulation of corticotropin-releasing hormone secretion|up regulation of corticotropin-releasing hormone secretion|positive regulation of corticotropin-releasing factor secretion|activation of corticotropin-releasing hormone secretion|stimulation of corticotropin-releasing hormone secretion|up-regulation of corticotropin-releasing hormone secretion													biological_process											owl:Class	
GO:0009153	biolink:NamedThing	purine deoxyribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine deoxyribonucleotide synthesis|purine deoxyribonucleotide biosynthesis|purine deoxyribonucleotide anabolism|purine deoxyribonucleotide formation													biological_process											owl:Class	
GO:1904850	biolink:NamedThing	negative regulation of establishment of protein localization to telomere	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere.	got7fsn_ti	down-regulation of establishment of protein localization to chromosome, telomeric region|inhibition of establishment of protein localization to telomere|negative regulation of establishment of protein localisation to telomere|down regulation of establishment of protein localisation to telomere|downregulation of establishment of protein localization to telomere|downregulation of establishment of protein localization to chromosome, telomeric region|down-regulation of establishment of protein localisation to telomere|downregulation of establishment of protein localisation to telomere|down regulation of establishment of protein localization to telomere|negative regulation of establishment of protein localization to chromosome, telomeric region|inhibition of establishment of protein localization to chromosome, telomeric region|down regulation of establishment of protein localization to chromosome, telomeric region|down-regulation of establishment of protein localization to telomere|inhibition of establishment of protein localisation to telomere						nc	2015-12-10T15:37:51Z						biological_process											owl:Class	
GO:0003783	biolink:NamedThing	obsolete barbed-end actin capping activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	barbed-end actin capping activity			GO:0051016	This term was made obsolete because it describes a biological process.					True				molecular_function											owl:Class	
GO:1901652	biolink:NamedThing	response to peptide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.	got7fsn_ti							pr	2012-11-20T09:45:15Z						biological_process											owl:Class	
GO:1901954	biolink:NamedThing	regulation of retrograde dense core granule transport	Any process that modulates the frequency, rate or extent of retrograde dense core granule transport.	got7fsn_ti							pr	2013-02-19T13:36:43Z						biological_process											owl:Class	
GO:1900404	biolink:NamedThing	positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of DNA repair.	got7fsn_ti	stimulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|up regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|up-regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|upregulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|activation of DNA repair by positive regulation of transcription from RNA polymerase II promoter						mah	2012-04-20T02:45:56Z						biological_process											owl:Class	
GO:2000028	biolink:NamedThing	regulation of photoperiodism, flowering	Any process that modulates the frequency, rate or extent of photoperiodism, flowering.	got7fsn_ti	regulation of photoperiodic control of flowering time|regulation of response to photoperiod, flowering|regulation of response to day length, flowering|regulation of response to night length, flowering|regulation of photoperiodic control of inflorescence development						tb	2010-08-05T11:27:18Z						biological_process											owl:Class	
GO:0031057	biolink:NamedThing	negative regulation of histone modification	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of a histone.	got7fsn_ti	downregulation of histone modification|down-regulation of histone modification|inhibition of histone modification|down regulation of histone modification													biological_process											owl:Class	
GO:0052502	biolink:NamedThing	obsolete positive regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	up regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway|upregulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|up-regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|induction by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|activation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|stimulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway|upregulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|activation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0035639	biolink:NamedThing	purine ribonucleoside triphosphate binding	Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine NTP binding						bf	2011-01-14T02:46:42Z						molecular_function											owl:Class	
GO:1904076	biolink:NamedThing	regulation of estrogen biosynthetic process	Any process that modulates the frequency, rate or extent of estrogen biosynthetic process.	got7fsn_ti	regulation of estrogen formation|regulation of oestrogen biosynthesis|regulation of estrogen anabolism|regulation of oestrogen biosynthetic process|regulation of estrogen biosynthesis|regulation of estrogen synthesis						tb	2015-03-20T16:56:14Z						biological_process											owl:Class	
GO:1904560	biolink:NamedThing	response to diphenidol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.	got7fsn_ti							mr	2015-08-14T16:09:31Z						biological_process											owl:Class	
GO:0045139	biolink:NamedThing	obsolete copper sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	copper sensitivity/resistance			GO:0046688	This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:1901338	biolink:NamedThing	catecholamine binding	Binding to catecholamine.	got7fsn_ti							bf	2012-09-03T14:08:44Z						molecular_function											owl:Class	
GO:1905019	biolink:NamedThing	negative regulation of methionine-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of methionine-tRNA ligase activity.	got7fsn_ti	downregulation of methionyl-tRNA synthetase activity|down regulation of MetRS activity|negative regulation of methionyl-transfer ribonucleate synthetase activity|down regulation of methionyl-transfer ribonucleate synthetase activity|down regulation of methionyl-transfer ribonucleic acid synthetase activity|downregulation of methionyl-transfer ribonucleate synthetase activity|inhibition of methionyl-tRNA synthetase activity|down-regulation of methionyl-transfer ribonucleic acid synthetase activity|negative regulation of methionyl-transfer RNA synthetase activity|inhibition of MetRS activity|downregulation of MetRS activity|downregulation of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of methionine translase activity|downregulation of methionine translase activity|negative regulation of methionyl-tRNA synthetase activity|negative regulation of methionine translase activity|negative regulation of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of methionine-tRNA ligase activity|down-regulation of MetRS activity|down-regulation of methionyl-tRNA synthetase activity|downregulation of methionine-tRNA ligase activity|inhibition of methionyl-transfer ribonucleate synthetase activity|inhibition of methionyl-transfer RNA synthetase activity|down-regulation of methionyl-transfer RNA synthetase activity|negative regulation of MetRS activity|down regulation of methionine-tRNA ligase activity|down regulation of methionyl-transfer RNA synthetase activity|negative regulation of methionyl-transfer ribonucleic acid synthetase activity|inhibition of methionine translase activity|inhibition of methionyl-transfer ribonucleic acid synthetase activity|down regulation of methionyl-tRNA synthetase activity|inhibition of L-methionine:tRNAMet ligase (AMP-forming)|down regulation of L-methionine:tRNAMet ligase (AMP-forming)|downregulation of methionyl-transfer RNA synthetase activity|inhibition of methionine-tRNA ligase activity|down-regulation of methionyl-transfer ribonucleate synthetase activity|downregulation of methionyl-transfer ribonucleic acid synthetase activity|down regulation of methionine translase activity						sl	2016-03-03T19:02:48Z						biological_process											owl:Class	
GO:0035793	biolink:NamedThing	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands.	got7fsn_ti	positive regulation of metanephric mesenchymal cell migration by PDGF receptor-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by betaPDGF receptor signaling pathway|positive regulation of metanephric mesenchymal cell migration by PDGFR-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway						bf	2011-04-11T01:30:03Z						biological_process											owl:Class	
GO:2000673	biolink:NamedThing	positive regulation of motor neuron apoptotic process	Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.	got7fsn_ti	positive regulation of motor neuron apoptosis|positive regulation of motoneuron apoptosis						pr	2011-05-09T10:56:24Z						biological_process											owl:Class	
GO:1901741	biolink:NamedThing	positive regulation of myoblast fusion	Any process that activates or increases the frequency, rate or extent of myoblast fusion.	got7fsn_ti	activation of myoblast fusion|up regulation of myoblast fusion|upregulation of myoblast fusion|up-regulation of myoblast fusion						rl	2013-01-11T20:24:03Z						biological_process											owl:Class	
GO:0051439	biolink:NamedThing	obsolete regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.	got7fsn_ti	mitotic ubiquitin-protein ligase regulator|mitotic anaphase-promoting complex regulator|mitotic ubiquitin ligase regulator|regulation of ubiquitin-protein ligase activity during mitotic cell cycle|mitotic APC regulator|mitotic SCF complex regulator|regulation of ubiquitin ligase activity during mitotic cell cycle				false					True				biological_process											owl:Class	
GO:0015469	biolink:NamedThing	obsolete channel-forming toxin activity	OBSOLETE. A toxin that exerts its effects by forming a channel in a membrane that allows the unregulated passage of substances into and out of the cell.	got7fsn_ti	channel-forming toxin activity				This term was made obsolete because it represents a class of gene products.	GO:0015267|GO:0035915|GO:0090729|GO:0046930				True				molecular_function											owl:Class	
GO:0099186	biolink:NamedThing	structural constituent of postsynapse	The action of a molecule that contributes to the structural integrity of a postsynapse.	got7fsn_ti							dos	2017-12-20T14:54:33Z						molecular_function											owl:Class	
GO:0006196	biolink:NamedThing	AMP catabolic process	The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate.	got7fsn_ti	AMP degradation|AMP breakdown|AMP catabolism													biological_process											owl:Class	
GO:0033092	biolink:NamedThing	positive regulation of immature T cell proliferation in thymus	Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.	got7fsn_ti	positive regulation of thymocyte proliferation|positive regulation of thymocyte cell proliferation|positive regulation of thymic T cell proliferation													biological_process											owl:Class	
GO:0010219	biolink:NamedThing	regulation of vernalization response	Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.	got7fsn_ti														biological_process											owl:Class	
GO:0080125	biolink:NamedThing	obsolete multicellular structure septum development	OBSOLETE. The process whose specific outcome is the progression of the multicellular structure septum over time, from its formation to the mature structure. The multicellular structure septum is the thin partition or membrane that divides a cavity or a mass of tissue.	got7fsn_ti					This term was made obsolete because it is not a useful grouping term.		dhl	2009-04-28T04:31:14Z		True				biological_process											owl:Class	
GO:0100042	biolink:NamedThing	obsolete negative regulation of pseudohyphal growth by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates pseudohyphal growth.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0010653	biolink:NamedThing	negative regulation of cell communication by chemical coupling	Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti														biological_process											owl:Class	
GO:0046247	biolink:NamedThing	terpene catabolic process	The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.	got7fsn_ti	terpene breakdown|terpene catabolism|terpene degradation													biological_process											owl:Class	
GO:0002688	biolink:NamedThing	regulation of leukocyte chemotaxis	Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.	got7fsn_ti	regulation of leucocyte chemotaxis|regulation of immune cell chemotaxis													biological_process											owl:Class	
GO:2000774	biolink:NamedThing	positive regulation of cellular senescence	Any process that activates or increases the frequency, rate or extent of cellular senescence.	got7fsn_ti							bf	2011-06-22T01:57:12Z						biological_process											owl:Class	
GO:0004086	biolink:NamedThing	obsolete carbamoyl-phosphate synthase activity	OBSOLETE. Catalysis of a reaction that results in the formation of carbamoyl phosphate.	got7fsn_ti	carbamoyl-phosphate synthase activity|carbamoyl phosphate synthase activity				This term was made obsolete because it is a grouping term based on name, rather than on function.	GO:0004088|GO:0004087				True				molecular_function											owl:Class	
GO:2001087	biolink:NamedThing	sophorose transport	The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T12:58:08Z						biological_process											owl:Class	
GO:0051102	biolink:NamedThing	DNA ligation involved in DNA recombination	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination.	got7fsn_ti	DNA ligation during DNA recombination													biological_process											owl:Class	
GO:0007108	biolink:NamedThing	obsolete cytokinesis, initiation of separation	OBSOLETE. The process involved in starting cell separation.	got7fsn_ti	initiation of separation involved in cytokinesis|cytokinesis, initiation of separation				This term was obsoleted because it was vaguely defined and had very likely been used in error. Consider the child terms of cytokinesis related to ring positioning, assembly, ring constriction etc. which would be more appropriate.					True				biological_process											owl:Class	
GO:0006257	biolink:NamedThing	dUDP catabolic process	The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate.	got7fsn_ti	dUDP degradation|dUDP catabolism|dUDP breakdown													biological_process											owl:Class	
GO:0015482	biolink:NamedThing	obsolete voltage-gated anion channel porin activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	voltage-gated anion channel porin activity|voltage-dependent anion channel porin activity				This term was made obsolete because it wrongly combines voltage-gated anion channel activity and porin activity.					True				molecular_function											owl:Class	
GO:1904096	biolink:NamedThing	protein tyrosine phosphatase complex	A protein complex which is capable of protein tyrosine phosphatase activity.	got7fsn_ti					An example of this is ACPP in human (UniProt symbol P15309) in PMID:22389722 (inferred from physical interaction).		bhm	2015-03-27T14:34:59Z						cellular_component											owl:Class	
GO:1900991	biolink:NamedThing	scopolamine biosynthetic process	The chemical reactions and pathways resulting in the formation of scopolamine.	got7fsn_ti	scopolamine formation|scopolamine biosynthesis|scopolamine synthesis|scopolamine anabolism						yaf	2012-06-14T09:48:07Z						biological_process											owl:Class	
GO:1904245	biolink:NamedThing	regulation of polynucleotide adenylyltransferase activity	Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity.	got7fsn_ti	regulation of polyadenylate nucleotidyltransferase activity|regulation of NTP polymerase activity|regulation of poly(A) polymerase activity|regulation of poly(A) hydrolase activity|regulation of poly-A polymerase activity|regulation of polyadenylic acid polymerase activity|regulation of polyadenylate synthetase activity|regulation of terminal riboadenylate transferase activity|regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|regulation of poly(A) synthetase activity|regulation of ATP:polynucleotidylexotransferase activity|regulation of polyadenylic polymerase activity|regulation of ATP:polynucleotide adenylyltransferase activity|regulation of ATP-polynucleotide adenylyltransferase activity|regulation of RNA adenylating enzyme activity|regulation of polyadenylate polymerase activity|regulation of AMP polynucleotidylexotransferase activity|regulation of RNA formation factors, PF1						kmv	2015-05-19T14:47:20Z						biological_process											owl:Class	
GO:1904653	biolink:NamedThing	regulation of lung alveolus development	Any process that modulates the frequency, rate or extent of lung alveolus development.	got7fsn_ti	regulation of alveologenesis|regulation of alveolarization						sl	2015-09-03T22:44:44Z						biological_process											owl:Class	
GO:0031651	biolink:NamedThing	negative regulation of heat generation	Any process that stops, prevents, or reduces the rate or extent of heat generation.	got7fsn_ti	down regulation of heat generation|downregulation of heat generation|inhibition of heat generation|down-regulation of heat generation													biological_process											owl:Class	
GO:0032436	biolink:NamedThing	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	got7fsn_ti	up regulation of proteasomal ubiquitin-dependent protein catabolic process|up-regulation of proteasomal ubiquitin-dependent protein catabolic process|activation of proteasomal ubiquitin-dependent protein catabolic process|stimulation of proteasomal ubiquitin-dependent protein catabolic process|upregulation of proteasomal ubiquitin-dependent protein catabolic process													biological_process											owl:Class	
GO:0005660	biolink:NamedThing	obsolete delta-DNA polymerase cofactor complex	OBSOLETE. A complex of proteins that interacts with delta-DNA polymerase, promoting elongation. In humans it is a heteropentamer of subunits of 140/145, 40, 38, 37 and 36.5 kDa, which form a complex with the proliferating cell nuclear antigen (PCNA) in the presence of ATP.	got7fsn_ti	delta-DNA polymerase cofactor complex|delta DNA polymerase cofactor complex				This term was made obsolete because it refers to two distinct complexes, PCNA and Replication factor C (RFC), the latter of which is already represented as a separate, unrelated GO term (DNA replication factor C complex ; GO:0005663). In addition, the phrase 'delta-DNA polymerase cofactor' to represent both PCNA and RFC is not used in current literature.	GO:0043626|GO:0005663				True				cellular_component											owl:Class	
GO:1904729	biolink:NamedThing	regulation of intestinal lipid absorption	Any process that modulates the frequency, rate or extent of intestinal lipid absorption.	got7fsn_ti							sl	2015-10-14T15:24:56Z						biological_process											owl:Class	
GO:0001086	biolink:NamedThing	obsolete transcription factor activity, TFIIA-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIA class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	got7fsn_ti	TFIIA-class binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001092	krc	2010-10-28T02:14:59Z		True				molecular_function											owl:Class	
GO:1903565	biolink:NamedThing	negative regulation of protein localization to cilium	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.	got7fsn_ti	downregulation of protein localization to cilium|down regulation of protein localization to cilium|down-regulation of protein localization to cilium|inhibition of protein localization to cilium						krc	2014-10-24T20:58:20Z						biological_process											owl:Class	
CHEBI:61197	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034116	biolink:NamedThing	positive regulation of heterotypic cell-cell adhesion	Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.	got7fsn_ti														biological_process											owl:Class	
CHEBI:27082	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090262	biolink:NamedThing	regulation of transcription-coupled nucleotide-excision repair	Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.	got7fsn_ti							tb	2010-02-03T04:27:42Z						biological_process											owl:Class	
GO:0045644	biolink:NamedThing	negative regulation of eosinophil differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation.	got7fsn_ti	inhibition of eosinophil differentiation|down regulation of eosinophil differentiation|down-regulation of eosinophil differentiation|downregulation of eosinophil differentiation													biological_process											owl:Class	
GO:0061618	biolink:NamedThing	obsolete sublamina densa	OBSOLETE. The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers.	got7fsn_ti					This term was made obsolete because it is thought to be an experimental artefact.		dph	2014-04-14T08:43:13Z		True				cellular_component											owl:Class	
GO:0071651	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 5 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.	got7fsn_ti	positive regulation of CCL5 production|positive regulation of RANTES production|positive regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:0051682	biolink:NamedThing	galactomannan catabolic process	The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.	got7fsn_ti														biological_process											owl:Class	
GO:2000488	biolink:NamedThing	positive regulation of brassinosteroid biosynthetic process	Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process.	got7fsn_ti	positive regulation of brassinosteroid synthesis|positive regulation of brassinosteroid anabolism|positive regulation of brassinosteroid formation|positive regulation of brassinosteroid biosynthesis						dhl	2011-03-11T06:48:45Z						biological_process											owl:Class	
GO:0010979	biolink:NamedThing	regulation of vitamin D 24-hydroxylase activity	Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.	got7fsn_ti							tb	2009-06-01T11:44:54Z						biological_process											owl:Class	
GO:1904598	biolink:NamedThing	positive regulation of connective tissue replacement involved in inflammatory response wound healing	Any process that activates or increases the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.	got7fsn_ti	positive regulation of fibrosis during inflammatory response|up-regulation of fibrosis during inflammatory response|upregulation of connective tissue replacement involved in inflammatory response wound healing|upregulation of fibrosis during inflammatory response|activation of connective tissue replacement involved in inflammatory response wound healing|up regulation of fibrosis during inflammatory response|up regulation of connective tissue replacement involved in inflammatory response wound healing|up-regulation of connective tissue replacement involved in inflammatory response wound healing|up regulation of connective tissue replacement during inflammatory response|positive regulation of connective tissue replacement during inflammatory response|activation of fibrosis during inflammatory response|activation of connective tissue replacement during inflammatory response|up-regulation of connective tissue replacement during inflammatory response|upregulation of connective tissue replacement during inflammatory response						krc	2015-08-25T20:52:36Z						biological_process											owl:Class	
GO:2000369	biolink:NamedThing	regulation of clathrin-dependent endocytosis	Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.	got7fsn_ti	regulation of clathrin-dependent endocytosis|regulation of clathrin-mediated endocytosis|regulation of clathrin coated pit-dependent endocytosis						mah	2011-02-09T12:36:18Z						biological_process											owl:Class	
GO:0019278	biolink:NamedThing	UDP-N-acetylgalactosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-N-acetylgalactosamine catabolism|UDP-N-acetylgalactosamine breakdown|UDP-N-acetylgalactosamine degradation													biological_process											owl:Class	
GO:0048778	biolink:NamedThing	regulation of erythrophore differentiation	Any process that modulates the frequency, rate or extent of erythrophore differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1901315	biolink:NamedThing	negative regulation of histone H2A K63-linked ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination.	got7fsn_ti	downregulation of histone H2A K63-linked ubiquitination|down regulation of histone H2A K63-linked ubiquitination|down-regulation of histone H2A K63-linked ubiquitination|inhibition of histone H2A K63-linked ubiquitination						tb	2012-08-22T20:29:24Z						biological_process											owl:Class	
GO:0044335	biolink:NamedThing	canonical Wnt signaling pathway involved in neural crest cell differentiation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in neural crest cell differentiation.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|canonical Wnt-activated signaling pathway involved in neural crest cell differentiation|canonical Wnt receptor signalling pathway involved in neural crest cell differentiation						jl	2010-08-20T03:02:34Z						biological_process											owl:Class	
GO:0071949	biolink:NamedThing	FAD binding	Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.	got7fsn_ti	oxidized flavin adenine dinucleotide binding|oxidized flavine-adenine dinucleotide binding						mah	2010-10-07T12:30:28Z						molecular_function											owl:Class	
GO:0046542	biolink:NamedThing	obsolete alpha-factor export	OBSOLETE. The directed movement of alpha-factor, one of the two yeast mating factors, out of a cell.	got7fsn_ti	alpha-factor export				This term was made obsolete because it is a gene product based term and it does not involve a unique process.	GO:0015833				True				biological_process											owl:Class	
GO:1905893	biolink:NamedThing	positive regulation of cellular response to thapsigargin	Any process that activates or increases the frequency, rate or extent of cellular response to thapsigargin.	got7fsn_ti	up-regulation of cellular response to thapsigargin|activation of cellular response to thapsigargin|upregulation of cellular response to thapsigargin|up regulation of cellular response to thapsigargin						bc	2017-02-01T11:36:24Z						biological_process											owl:Class	
GO:0072045	biolink:NamedThing	convergent extension involved in nephron morphogenesis	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.	got7fsn_ti							mah	2010-01-25T03:22:47Z						biological_process											owl:Class	
GO:1902936	biolink:NamedThing	phosphatidylinositol bisphosphate binding	Binding to phosphatidylinositol bisphosphate.	got7fsn_ti					An example of this is KCNJ2 in human (P63252) in PMID:18690034 (inferred from direct assay)		bhm	2014-04-25T15:14:12Z						molecular_function											owl:Class	
GO:1990368	biolink:NamedThing	obsolete process resulting in tolerance to hydrolysate	OBSOLETE. A response that results in a state of tolerance to hydrolysate (product of hydrolysis).	got7fsn_ti	process resulting in tolerance to hydrolysate				This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:27:51Z		True				biological_process											owl:Class	
GO:1904550	biolink:NamedThing	response to arachidonic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.	got7fsn_ti							sl	2015-08-13T20:53:24Z						biological_process											owl:Class	
GO:0031938	biolink:NamedThing	obsolete regulation of chromatin silencing at telomere	OBSOLETE. Any process that affects the rate, extent or location of chromatin silencing at telomeres.	got7fsn_ti	regulation of heterochromatic silencing at telomere	https://github.com/geneontology/go-ontology/issues/22027			This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.	GO:0031509				True				biological_process											owl:Class	
GO:0060861	biolink:NamedThing	positive regulation of floral organ abscission	Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.	got7fsn_ti							dph	2009-08-12T04:03:09Z						biological_process											owl:Class	
GO:0090321	biolink:NamedThing	positive regulation of chylomicron remnant clearance	Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.	got7fsn_ti							tb	2010-04-30T10:20:26Z						biological_process											owl:Class	
GO:1904870	biolink:NamedThing	negative regulation of protein localization to Cajal body	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body.	got7fsn_ti	down regulation of protein localization in Cajal body|downregulation of protein localisation to Cajal body|downregulation of protein localisation in Cajal body|down regulation of protein localization to Cajal body|negative regulation of protein localization in Cajal body|inhibition of protein localisation to Cajal body|inhibition of protein localization to Cajal body|down-regulation of protein localisation to Cajal body|down-regulation of protein localization in Cajal body|downregulation of protein localization to Cajal body|down regulation of protein localisation to Cajal body|down-regulation of protein localisation in Cajal body|down regulation of protein localisation in Cajal body|inhibition of protein localization in Cajal body|negative regulation of protein localisation in Cajal body|downregulation of protein localization in Cajal body|inhibition of protein localisation in Cajal body|negative regulation of protein localisation to Cajal body|down-regulation of protein localization to Cajal body						nc	2015-12-18T11:17:38Z						biological_process											owl:Class	
GO:0002530	biolink:NamedThing	regulation of systemic arterial blood pressure involved in acute-phase response	Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.	got7fsn_ti	regulation of systemic arterial blood pressure during acute phase response|blood pressure regulation during acute phase response													biological_process											owl:Class	
GO:2000777	biolink:NamedThing	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia	Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.	got7fsn_ti	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to lowered oxygen tension|positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxic stress						mah	2011-06-22T04:07:20Z						biological_process											owl:Class	
GO:0045856	biolink:NamedThing	positive regulation of pole plasm oskar mRNA localization	Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.	got7fsn_ti	up-regulation of pole plasm oskar mRNA localization|up regulation of pole plasm oskar mRNA localization|positive regulation of oocyte pole plasm oskar mRNA localization|activation of pole plasm oskar mRNA localization|upregulation of pole plasm oskar mRNA localization|stimulation of pole plasm oskar mRNA localization|positive regulation of pole plasm oskar mRNA localisation													biological_process											owl:Class	
GO:1904321	biolink:NamedThing	response to forskolin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.	got7fsn_ti							sl	2015-06-10T19:01:27Z						biological_process											owl:Class	
GO:0052863	biolink:NamedThing	1-deoxy-D-xylulose 5-phosphate metabolic process	The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.	got7fsn_ti	1-deoxy-D-xylulose 5-phosphate metabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolic process													biological_process											owl:Class	
GO:0060631	biolink:NamedThing	regulation of meiosis I	Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.	got7fsn_ti							dph	2009-05-18T02:55:19Z						biological_process											owl:Class	
GO:2000399	biolink:NamedThing	negative regulation of thymocyte aggregation	Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation.	got7fsn_ti	negative regulation of immature T-cell aggregation|negative regulation of immature T-lymphocyte aggregation|negative regulation of immature T cell aggregation|negative regulation of T cell precursor aggregation|negative regulation of thymic lymphocyte aggregation						mah	2011-02-22T02:49:44Z						biological_process											owl:Class	
CHEBI:83821	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006439	biolink:NamedThing	obsolete aminoacyl-tRNA hydrolase reaction	OBSOLETE. Hydrolysis of the peptidyl-tRNA by aminoacyl-tRNA hydrolase upon termination of translation. Analogous to usual peptidyl transfer during elongation, except that the acceptor is H2O instead of an aminoacyl-tRNA.	got7fsn_ti	aminoacyl-tRNA hydrolase reaction			GO:0004045	This term was made obsolete because it represents a molecular function.					True				biological_process											owl:Class	
GO:0034035	biolink:NamedThing	purine ribonucleoside bisphosphate metabolic process	The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	purine ribonucleoside bisphosphate metabolism													biological_process											owl:Class	
GO:2001124	biolink:NamedThing	regulation of translational frameshifting	Any process that modulates the frequency, rate or extent of translational frameshifting.	got7fsn_ti							dph	2011-10-12T05:52:22Z						biological_process											owl:Class	
GO:0098949	biolink:NamedThing	intrinsic component of postsynaptic endosome membrane	The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to postsynaptic endosome membrane													cellular_component											owl:Class	
GO:1903860	biolink:NamedThing	negative regulation of dendrite extension	Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension.	got7fsn_ti	up-regulation of dendrite retraction|down-regulation of dendrite extension|up regulation of dendrite retraction|down regulation of dendrite extension|downregulation of dendrite extension|inhibition of dendrite extension				An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype.		pad	2015-02-02T15:34:00Z						biological_process											owl:Class	
GO:0039568	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by inhibition of DNA binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces STAT1-dependent gene transcription, by preventing STAT1 from binding to promoter sites in the nucleus.	got7fsn_ti	suppression by virus of host STAT1 activity by negative regulation of DNA binding|inhibition of DNA binding of STAT1				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:31:58Z		True				biological_process											owl:Class	
UBERON:0001184	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035417	biolink:NamedThing	obsolete negative regulation of mitotic prometaphase	OBSOLETE. Any process that stops, prevents or reduces the rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.	got7fsn_ti	negative regulation of mitotic prometaphase				This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		bf	2010-03-29T10:53:42Z		True				biological_process											owl:Class	
GO:0090235	biolink:NamedThing	regulation of metaphase plate congression	Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.	got7fsn_ti	regulation of chromosome congression						tb	2010-01-20T11:05:55Z						biological_process											owl:Class	
GO:1904770	biolink:NamedThing	intramembranous bone morphogenesis	The developmental process by which an intramembranous bone is generated and organized.	got7fsn_ti	intramembranous bones morphogenesis|membrane bone morphogenesis						dos	2015-10-28T11:46:04Z						biological_process											owl:Class	
GO:0035307	biolink:NamedThing	positive regulation of protein dephosphorylation	Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.	got7fsn_ti	activation of protein amino acid dephosphorylation|up-regulation of protein amino acid dephosphorylation|upregulation of protein amino acid dephosphorylation|stimulation of protein amino acid dephosphorylation|positive regulation of protein amino acid dephosphorylation|up regulation of protein amino acid dephosphorylation													biological_process											owl:Class	
GO:0030513	biolink:NamedThing	positive regulation of BMP signaling pathway	Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.	got7fsn_ti	up regulation of BMP signaling pathway|positive regulation of decapentaplegic receptor signaling pathway|positive regulation of bone morphogenetic protein signaling pathway|stimulation of BMP signaling pathway|positive regulation of BMP signalling pathway|up-regulation of BMP signaling pathway|activation of BMP signaling pathway|positive regulation of bone morphogenetic protein signalling pathway|positive regulation of decapentaplegic signaling pathway|positive regulation of decapentaplegic receptor signalling pathway|positive regulation of BMP receptor signaling pathway|upregulation of BMP signaling pathway						tb	2009-11-13T10:50:41Z			GO:0090098			biological_process											owl:Class	
GO:1903644	biolink:NamedThing	regulation of chaperone-mediated protein folding	Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding.	got7fsn_ti							pga	2014-11-21T15:25:27Z						biological_process											owl:Class	
GO:0071298	biolink:NamedThing	cellular response to L-ascorbic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.	got7fsn_ti	cellular response to ascorbic acid|cellular response to vitamin C|cellular response to L-ascorbate						mah	2009-12-10T04:29:19Z						biological_process											owl:Class	
GO:0000200	biolink:NamedThing	obsolete inactivation of MAPK activity involved in cell wall organization or biogenesis	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of cell wall organization or biogenesis.	got7fsn_ti	inactivation of MAPK activity involved in cell wall integrity|termination of MAPK activity during cell wall biogenesis|cell wall biogenesis, termination of MAPK activity|cell wall biogenesis, inactivation of MAPK activity|inactivation of MAPK activity involved in cell wall organization or biogenesis	https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0010642	biolink:NamedThing	negative regulation of platelet-derived growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.	got7fsn_ti	negative regulation of platelet-derived growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0110107	biolink:NamedThing	regulation of imaginal disc-derived wing vein specification	Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification.	got7fsn_ti							kmv	2018-07-05T13:44:08Z						biological_process											owl:Class	
GO:0002256	biolink:NamedThing	regulation of kinin cascade	Any process that modulates the frequency, rate, or extent of the kinin cascade.	got7fsn_ti														biological_process											owl:Class	
GO:0015062	biolink:NamedThing	obsolete violet-sensitive opsin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	violet-sensitive opsin				This term was made obsolete because it refers to a class of proteins.	GO:0016918|GO:0009881|GO:0046876|GO:0016021|GO:0007603|GO:0009588				True				molecular_function											owl:Class	
GO:0048302	biolink:NamedThing	regulation of isotype switching to IgG isotypes	Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.	got7fsn_ti	regulation of class switching to IgG isotypes|regulation of class switch recombination to IgG isotypes|regulation of isotype switch recombination to IgG isotypes													biological_process											owl:Class	
GO:1905609	biolink:NamedThing	positive regulation of smooth muscle cell-matrix adhesion	Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion.	got7fsn_ti	up regulation of smooth muscle cell-matrix adhesion|upregulation of smooth muscle cell-matrix adhesion|up-regulation of smooth muscle cell-matrix adhesion|activation of smooth muscle cell-matrix adhesion						sl	2016-10-27T21:58:11Z						biological_process											owl:Class	
GO:0016596	biolink:NamedThing	thienylcyclohexylpiperidine binding	Binding to thienylcyclohexylpiperidine.	got7fsn_ti	TCP binding													molecular_function											owl:Class	
CHEBI:156132	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904539	biolink:NamedThing	negative regulation of glycolytic process through fructose-6-phosphate	Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.	got7fsn_ti	inhibition of glycolytic process through fructose-6-phosphate|down-regulation of glycolytic process through fructose-6-phosphate|downregulation of glycolysis through fructose-6-phosphate|down regulation of glycolytic process through fructose-6-phosphate|down-regulation of glycolysis through fructose-6-phosphate|down regulation of glycolysis through fructose-6-phosphate|negative regulation of glycolysis through fructose-6-phosphate|inhibition of glycolysis through fructose-6-phosphate|downregulation of glycolytic process through fructose-6-phosphate						dph	2015-08-07T11:35:16Z						biological_process											owl:Class	
UBERON:0000965	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900091	biolink:NamedThing	regulation of raffinose biosynthetic process	Any process that modulates the frequency, rate or extent of raffinose biosynthetic process.	got7fsn_ti	regulation of raffinose anabolism|regulation of raffinose biosynthesis|regulation of raffinose synthesis|regulation of raffinose formation						dhl	2012-02-08T06:31:54Z						biological_process											owl:Class	
GO:0052505	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont cell wall callose deposition	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of defense-related symbiont cell wall callose deposition|positive regulation by organism of defense-related symbiont cell wall callose deposition				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0042739	biolink:NamedThing	obsolete endogenous drug catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a drug that has originated internally within the cell or organism.	got7fsn_ti	endogenous drug breakdown|endogenous drug degradation|endogenous drug catabolism	https://github.com/geneontology/go-ontology/issues/21819			The reason for obsoletion is that there is no evidence that this process exists as a drug is by definition exogenous.					True				biological_process											owl:Class	
GO:1901486	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process	OBSOLETE. Positive regulation of transcription factor catabolism that results in negative regulation of the SREBP signaling pathway.	got7fsn_ti	negative regulation of SREBP-mediated signaling pathway by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation|negative regulation of SREBP-mediated signalling pathway by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolism				The reason for obsoletion is that this term should be represented by a GO-CAM model.		bf	2012-10-09T08:23:26Z		True				biological_process											owl:Class	
GO:0043090	biolink:NamedThing	amino acid import	The directed movement of amino acids into a cell or organelle.	got7fsn_ti	amino acid uptake													biological_process											owl:Class	
GO:1901527	biolink:NamedThing	abscisic acid-activated signaling pathway involved in stomatal movement	Any abscisic acid mediated signaling pathway that is involved in stomatal movement.	got7fsn_ti	abscisic acid mediated signalling involved in stomatal movement|abscisic acid mediated signaling pathway involved in stomatal movement						tb	2012-10-23T23:09:34Z						biological_process											owl:Class	
GO:0048781	biolink:NamedThing	regulation of cyanophore differentiation	Any process that modulates the frequency, rate or extent of cyanophore differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1902594	biolink:NamedThing	multi-organism nuclear import	A nuclear import which involves another organism.	got7fsn_ti	multi organism nuclear import						jl	2013-12-19T15:26:43Z						biological_process											owl:Class	
GO:0035440	biolink:NamedThing	tuberculosinol biosynthetic process	The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.	got7fsn_ti	tuberculosinol biosynthesis|halima-5,6,dien-15-ol biosynthetic process|halima-5,6,dien-15-ol biosynthesis						bf	2010-04-09T03:36:19Z				MetaCyc:PWY-5935		biological_process											owl:Class	
CHEBI:246422	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006173	biolink:NamedThing	dADP biosynthetic process	The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).	got7fsn_ti	dADP formation|dADP biosynthesis|dADP anabolism|dADP synthesis													biological_process											owl:Class	
GO:1904046	biolink:NamedThing	negative regulation of vascular endothelial growth factor production	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production.	got7fsn_ti	down regulation of vascular endothelial growth factor production|down-regulation of vascular endothelial growth factor production|downregulation of VEGF production|down-regulation of VEGF production|downregulation of vascular endothelial growth factor production|negative regulation of VEGF production|inhibition of VEGF production|inhibition of vascular endothelial growth factor production|down regulation of VEGF production						sl	2015-03-16T23:27:06Z						biological_process											owl:Class	
GO:0140346	biolink:NamedThing	phosphatidylserine flippase activity	Catalysis of the movement of phosphatidylserine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	phosphatidylserine flippase activity (exoplasmic to cytosolic leaftlet)						pg	2019-05-16T13:44:23Z						molecular_function											owl:Class	
GO:1904705	biolink:NamedThing	regulation of vascular associated smooth muscle cell proliferation	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation.	got7fsn_ti	regulation of vascular smooth muscle cell proliferation|regulation of VSMC proliferation						sl	2015-10-01T16:05:20Z						biological_process											owl:Class	
GO:0050925	biolink:NamedThing	negative regulation of negative chemotaxis	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.	got7fsn_ti	downregulation of negative chemotaxis|down regulation of negative chemotaxis|down-regulation of negative chemotaxis|inhibition of negative chemotaxis													biological_process											owl:Class	
GO:0004278	biolink:NamedThing	obsolete granzyme B activity	OBSOLETE. Catalysis of the preferential cleavage of Asp-Xaa > Asn-Xaa > Met-Xaa, Ser-Xaa.	got7fsn_ti	CCP1 proteinase|granzyme H|cytotoxic cell proteinase-1|granzyme G|cytotoxic t-lymphocyte proteinase 2 activity|CTLA1|CCPII|granzyme B activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905640	biolink:NamedThing	response to acetaldehyde	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.	got7fsn_ti							mah	2016-11-04T15:07:18Z						biological_process											owl:Class	
GO:0042845	biolink:NamedThing	glycol biosynthetic process	The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.	got7fsn_ti	glycol anabolism|glycol synthesis|dihydric alcohol biosynthesis|glycol formation|dihydric alcohol biosynthetic process|glycol biosynthesis													biological_process											owl:Class	
GO:0075295	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902444	biolink:NamedThing	riboflavin binding	Binding to riboflavin.	got7fsn_ti							al	2013-10-11T08:44:52Z						molecular_function											owl:Class	
GO:0100012	biolink:NamedThing	regulation of heart induction by canonical Wnt signaling pathway	Any canonical Wnt signaling pathway process that regulates heart induction.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
GO:0048088	biolink:NamedThing	regulation of male pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.	got7fsn_ti														biological_process											owl:Class	
GO:0009467	biolink:NamedThing	obsolete monoheme class I cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	monoheme class I cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:1901923	biolink:NamedThing	negative regulation of sclerotium development	Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development.	got7fsn_ti	down regulation of sclerotium development|down-regulation of sclerotium development|inhibition of sclerotium development|downregulation of sclerotium development						di	2013-02-15T20:00:23Z						biological_process											owl:Class	
GO:0008130	biolink:NamedThing	obsolete neutrophil collagenase activity	OBSOLETE. Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.	got7fsn_ti	matrix metalloproteinase 8 activity|neutrophil collagenase activity|MMP-8|PMNL collagenase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0048697	biolink:NamedThing	positive regulation of collateral sprouting in absence of injury	Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury.	got7fsn_ti	stimulation of collateral sprouting in the absence of injury|activation of collateral sprouting in the absence of injury|upregulation of collateral sprouting in the absence of injury|up-regulation of collateral sprouting in the absence of injury|up regulation of collateral sprouting in the absence of injury													biological_process											owl:Class	
GO:0009406	biolink:NamedThing	obsolete virulence	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	virulence				This term was made obsolete because it represents a phenotype rather than a biological process.	GO:0090729|GO:0016032				True				biological_process											owl:Class	
GO:1903323	biolink:NamedThing	regulation of snoRNA metabolic process	Any process that modulates the frequency, rate or extent of snoRNA metabolic process.	got7fsn_ti	regulation of snoRNA metabolism						vw	2014-08-18T13:05:17Z						biological_process											owl:Class	
GO:0052451	biolink:NamedThing	obsolete modulation by organism of symbiont inflammatory response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont inflammatory response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0051390	biolink:NamedThing	obsolete inactivation of MAPKKK activity	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase kinase kinase (MAPKKK).	got7fsn_ti	termination of MAP kinase kinase kinase activity|inactivation of MAP kinase kinase kinase activity|termination of MAPKKK activity	https://github.com/geneontology/go-ontology/issues/21308			This term was obsoleted because it represents a molecular function.	GO:0030291|GO:0043409				True				biological_process											owl:Class	
GO:0010765	biolink:NamedThing	positive regulation of sodium ion transport	Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1905860	biolink:NamedThing	positive regulation of heparan sulfate proteoglycan binding	Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding.	got7fsn_ti	up-regulation of heparin proteoglycan binding|positive regulation of heparin proteoglycan binding|up regulation of heparin proteoglycan binding|activation of heparin proteoglycan binding|upregulation of heparin proteoglycan binding|up regulation of heparan sulfate proteoglycan binding|up-regulation of heparan sulfate proteoglycan binding|upregulation of heparan sulfate proteoglycan binding|activation of heparan sulfate proteoglycan binding						bc	2017-01-23T14:25:27Z						biological_process											owl:Class	
GO:1900340	biolink:NamedThing	negative regulation of methane biosynthetic process from formic acid	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from formic acid.	got7fsn_ti	down-regulation of methane biosynthetic process from formic acid|inhibition of methane biosynthetic process from formic acid|downregulation of methane biosynthetic process from formic acid|down regulation of methane biosynthetic process from formic acid						tt	2012-04-06T02:05:03Z						biological_process											owl:Class	
GO:0016527	biolink:NamedThing	obsolete brain-specific angiogenesis inhibitor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	brain-specific angiogenesis inhibitor activity				This term was made obsolete because it is based on anatomical information, and describes at least one gene product. It has also never been defined.	GO:0004930				True				molecular_function											owl:Class	
GO:0006410	biolink:NamedThing	obsolete transcription, RNA-dependent	OBSOLETE. The cellular synthesis of DNA on a template of RNA.	got7fsn_ti	transcription, RNA-dependent				This term was obsoleted because the name and the definition mean two completely different things: 1) "transcription, RNA-dependent", i.e. RNA-dependent production of an RNA transcript and 2) "reverse transcription", i.e. RNA-dependent DNA synthesis.					True				biological_process											owl:Class	
CHEBI:22603	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903474	biolink:NamedThing	obsolete anchoring of the mitotic actomyosin contractile ring to the plasma membrane	OBSOLETE. A process that maintains the mitotic actinomyosin contractile ring at the plasma membrane.	got7fsn_ti	cytokinetic ring anchoring involved in mitotic cell cycle|maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle				The reason for obsoletion is that this term represents a GO-CAM model.		vw	2014-09-23T14:12:48Z		True				biological_process											owl:Class	
GO:0051859	biolink:NamedThing	obsolete suppression of symbiont defenses	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont defense(s) by active mechanisms that normally result in the shutting down of a symbiont pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14862			This term was made obsolete because it is not relevant for the host in a host-symbiont interaction.					True				biological_process											owl:Class	
GO:1901537	biolink:NamedThing	positive regulation of DNA demethylation	Any process that activates or increases the frequency, rate or extent of DNA demethylation.	got7fsn_ti	activation of DNA demethylation|up regulation of DNA demethylation|up-regulation of DNA demethylation|upregulation of DNA demethylation						jl	2012-10-24T13:52:59Z						biological_process											owl:Class	
GO:0046349	biolink:NamedThing	amino sugar biosynthetic process	The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group.	got7fsn_ti	amino sugar biosynthesis|amino sugar anabolism|aminosaccharide biosynthesis|amino sugar synthesis|amino sugar formation|aminosaccharide biosynthetic process													biological_process											owl:Class	
GO:1903917	biolink:NamedThing	positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.	got7fsn_ti	up-regulation of eIF2alpha dephosphorylation in response to ER stress|activation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|activation of eIF2alpha dephosphorylation in response to ER stress|positive regulation of ER stress-induced eIF2 alpha dephosphorylation|up-regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up-regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of eIF2alpha dephosphorylation in response to ER stress|activation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up regulation of eIF2alpha dephosphorylation in response to ER stress|positive regulation of eIF2alpha dephosphorylation in response to ER stress|up regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress						bf	2015-02-09T11:18:24Z						biological_process											owl:Class	
GO:0005648	biolink:NamedThing	obsolete importin, beta-subunit	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	karyopherin-beta1|importin, beta-subunit				This term was made obsolete because it represents a single gene product and not a complex.	GO:0017056|GO:0005634|GO:0005643|GO:0005737				True				cellular_component											owl:Class	
GO:0051296	biolink:NamedThing	establishment of meiotic spindle orientation	Any process that set the alignment of meiotic spindle relative to other cellular structures.	got7fsn_ti	establishment of spindle orientation involved in meiotic cell cycle|orienting of meiotic spindle|meiotic spindle orientation|establishment of spindle orientation during meiosis													biological_process											owl:Class	
GO:0001805	biolink:NamedThing	positive regulation of type III hypersensitivity	Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.	got7fsn_ti	up regulation of type III hypersensitivity|stimulation of type III hypersensitivity|upregulation of type III hypersensitivity|up-regulation of type III hypersensitivity|activation of type III hypersensitivity													biological_process											owl:Class	
GO:0042655	biolink:NamedThing	obsolete activation of JNKKK activity	OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase kinase kinase (JNKKK) activity.	got7fsn_ti	activation of JUN kinase kinase kinase activity|positive regulation of JUNKKK activity	https://github.com/geneontology/go-ontology/issues/21307			This term was obsoleted because it represents a molecular function.	GO:0043539|GO:0007254				True				biological_process											owl:Class	
GO:0005029	biolink:NamedThing	obsolete CD27 receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	CD27 receptor activity				This term was made obsolete because it describes the receptor type, and not an activity.	GO:0042614				True				molecular_function											owl:Class	
GO:0120328	biolink:NamedThing	ATP-dependent DNA (cytosine-5-)-methyltransferase activity	Catalytic activity that acts to transfer a methyl group to a DNA molecule, driven by ATP hydrolysis.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21872					krc	2021-08-16T21:00:16Z						molecular_function											owl:Class	
GO:0046499	biolink:NamedThing	S-adenosylmethioninamine metabolic process	The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.	got7fsn_ti	S-adenosylmethioninamine metabolism													biological_process											owl:Class	
GO:0032524	biolink:NamedThing	obsolete nutrient export	OBSOLETE. The directed movement of nutrients out of a cell or organelle.	got7fsn_ti	nutrient export				This term was made obsolete because "nutrient" is not defined, and does not have a consistent meaning.	GO:0006810				True				biological_process											owl:Class	
GO:1903096	biolink:NamedThing	protein localization to meiotic spindle midzone	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone.	got7fsn_ti	protein localisation in meiotic spindle midzone|protein localization in meiotic spindle midzone|protein localisation to meiotic spindle midzone						kmv	2014-06-03T16:06:22Z						biological_process											owl:Class	
CHEBI:26401	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905247	biolink:NamedThing	positive regulation of aspartic-type peptidase activity	Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity.	got7fsn_ti	up regulation of aspartic-type peptidase activity|up-regulation of aspartic-type peptidase activity|upregulation of aspartic-type peptidase activity|activation of aspartic-type peptidase activity						jl	2016-06-09T11:55:55Z						biological_process											owl:Class	
GO:0002923	biolink:NamedThing	regulation of humoral immune response mediated by circulating immunoglobulin	Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.	got7fsn_ti														biological_process											owl:Class	
GO:0046172	biolink:NamedThing	octanol catabolic process	The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH.	got7fsn_ti	octanol breakdown|octanol degradation|octanol catabolism													biological_process											owl:Class	
GO:0019406	biolink:NamedThing	hexitol biosynthetic process	The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule.	got7fsn_ti	hexitol synthesis|hexitol biosynthesis|hexitol formation|hexitol anabolism													biological_process											owl:Class	
GO:0062033	biolink:NamedThing	positive regulation of mitotic sister chromatid segregation	Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.	got7fsn_ti							dph	2018-04-23T14:32:23Z						biological_process											owl:Class	
GO:0003800	biolink:NamedThing	obsolete antiviral response protein activity	OBSOLETE. A protein involved in an antiviral response.	got7fsn_ti	antiviral response protein activity				This term was made obsolete because it refers to involvement in a biological process.	GO:0009615				True				molecular_function											owl:Class	
GO:1905883	biolink:NamedThing	regulation of triglyceride transport	Any process that modulates the frequency, rate or extent of triglyceride transport.	got7fsn_ti	regulation of triacylglycerol transport						rz	2017-01-31T11:32:29Z						biological_process											owl:Class	
GO:1903539	biolink:NamedThing	protein localization to postsynaptic membrane	A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane.	got7fsn_ti	protein localization in postsynaptic membrane|protein localisation to postsynaptic membrane|protein localisation in postsynaptic membrane						kmv	2014-10-10T11:23:53Z						biological_process											owl:Class	
GO:0004191	biolink:NamedThing	obsolete barrierpepsin activity	OBSOLETE. Catalysis of the selected cleavage of the Leu6-Lys7 bond in the pheromone alpha-mating factor.	got7fsn_ti	extracellular 'barrier' protein activity|barrierpepsin activity|barrier proteinase activity|Bar proteinase activity			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0010523	biolink:NamedThing	negative regulation of calcium ion transport into cytosol	Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.	got7fsn_ti														biological_process											owl:Class	
GO:1990546	biolink:NamedThing	mitochondrial tricarboxylic acid transmembrane transport	The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:00:14Z						biological_process											owl:Class	
GO:1905045	biolink:NamedThing	negative regulation of Schwann cell proliferation involved in axon regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.	got7fsn_ti	downregulation of Schwann cell proliferation involved in axon regeneration|down-regulation of Schwann cell proliferation involved in axon regeneration|inhibition of Schwann cell proliferation involved in axon regeneration|down regulation of Schwann cell proliferation involved in axon regeneration						rph	2016-03-11T14:47:45Z						biological_process											owl:Class	
GO:0045670	biolink:NamedThing	regulation of osteoclast differentiation	Any process that modulates the frequency, rate or extent of osteoclast differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0140620	biolink:NamedThing	DNA strand exchange inhibitor activity	Binds to and stops, prevents or reduces a DNA strand exchange activity.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20964					pg	2021-02-26T17:57:00Z						molecular_function											owl:Class	
GO:1900535	biolink:NamedThing	palmitic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of palmitic acid.	got7fsn_ti							tb	2012-05-09T07:05:17Z						biological_process											owl:Class	
GO:1902003	biolink:NamedThing	regulation of amyloid-beta formation	Any process that modulates the frequency, rate or extent of amyloid-beta formation.	got7fsn_ti	regulation of beta-amyloid formation						dph	2013-03-21T19:59:26Z						biological_process											owl:Class	
GO:0042854	biolink:NamedThing	eugenol metabolic process	The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.	got7fsn_ti	eugenic acid metabolic process|eugenol metabolism|4-allyl-2-methoxyphenol metabolism|4-allyl-2-methoxyphenol metabolic process|eugenic acid metabolism													biological_process											owl:Class	
GO:0033343	biolink:NamedThing	positive regulation of collagen binding	Any process that activates or increases the frequency, rate or extent of collagen binding.	got7fsn_ti	activation of collagen binding|up-regulation of collagen binding|upregulation of collagen binding|stimulation of collagen binding|up regulation of collagen binding													biological_process											owl:Class	
GO:0052308	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction	OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism during symbiotic interaction|pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism involved in symbiotic interaction				This term was obsoleted because it has been misused.	GO:0052034|GO:0002221|GO:0002752				True				biological_process											owl:Class	
GO:1903316	biolink:NamedThing	positive regulation of nitrogen cycle metabolic process	Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process.	got7fsn_ti	upregulation of nitrogen cycle metabolic process|activation of nitrogen cycle metabolic process|up-regulation of nitrogen cycle metabolic process|up regulation of nitrogen cycle metabolic process						vw	2014-08-18T12:57:50Z						biological_process											owl:Class	
GO:1900656	biolink:NamedThing	negative regulation of diorcinol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process.	got7fsn_ti	down regulation of diorcinol synthesis|inhibition of diorcinol anabolism|inhibition of diorcinol biosynthesis|down-regulation of diorcinol biosynthesis|negative regulation of diorcinol synthesis|inhibition of diorcinol formation|inhibition of diorcinol biosynthetic process|negative regulation of diorcinol formation|downregulation of diorcinol biosynthetic process|negative regulation of diorcinol anabolism|down regulation of diorcinol biosynthesis|downregulation of diorcinol formation|down-regulation of diorcinol synthesis|down regulation of diorcinol anabolism|down-regulation of diorcinol anabolism|down-regulation of diorcinol biosynthetic process|down-regulation of diorcinol formation|down regulation of diorcinol biosynthetic process|down regulation of diorcinol formation|downregulation of diorcinol anabolism|downregulation of diorcinol synthesis|negative regulation of diorcinol biosynthesis|inhibition of diorcinol synthesis|downregulation of diorcinol biosynthesis						di	2012-05-22T04:09:01Z						biological_process											owl:Class	
GO:0006988	biolink:NamedThing	obsolete unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor				This term was made obsolete because it represents a function rather than a process.	GO:0004521				True				biological_process											owl:Class	
GO:0001808	biolink:NamedThing	negative regulation of type IV hypersensitivity	Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response.	got7fsn_ti	down-regulation of type IV hypersensitivity|downregulation of type IV hypersensitivity|down regulation of type IV hypersensitivity|inhibition of type IV hypersensitivity													biological_process											owl:Class	
GO:1903899	biolink:NamedThing	positive regulation of PERK-mediated unfolded protein response	Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response.	got7fsn_ti	positive regulation of PKR-like ER kinase signal transduction|positive regulation of PERK signaling in response to endoplasmic reticulum stress|activation of UPR signaling by PERK stress sensor|upregulation of PERK signaling in response to endoplasmic reticulum stress|up-regulation of PERK branch of UPR|activation of PERK branch of UPR|up regulation of PKR-like ER kinase signal transduction|up regulation of PERK signaling in response to endoplasmic reticulum stress|up-regulation of endoplasmic reticulum unfolded protein response; PERK signaling|up regulation of PERK branch of UPR|upregulation of PKR-like ER kinase signal transduction|positive regulation of endoplasmic reticulum unfolded protein response; PERK signaling|positive regulation of EIF2AK3-mediated unfolded protein response|activation of endoplasmic reticulum unfolded protein response; PERK signaling|activation of PERK-mediated unfolded protein response|upregulation of PERK branch of UPR|upregulation of PERK-mediated unfolded protein response|up-regulation of UPR signaling by PERK stress sensor|activation of PKR-like ER kinase signal transduction|up-regulation of PERK-mediated unfolded protein response|upregulation of endoplasmic reticulum unfolded protein response; PERK signaling|up-regulation of PERK signaling in response to endoplasmic reticulum stress|up regulation of UPR signaling by PERK stress sensor|positive regulation of UPR signaling by PERK stress sensor|upregulation of UPR signaling by PERK stress sensor|activation of PERK signaling in response to endoplasmic reticulum stress|up regulation of endoplasmic reticulum unfolded protein response; PERK signaling|up-regulation of PKR-like ER kinase signal transduction|positive regulation of PERK branch of UPR|up regulation of PERK-mediated unfolded protein response						bf	2015-02-09T10:18:32Z						biological_process											owl:Class	
GO:0015507	biolink:NamedThing	obsolete hydroxy/aromatic amino acid permease activity	OBSOLETE. Permease for hydroxy and aromatic amino acids.	got7fsn_ti	hydroxy/aromatic amino acid permease activity				This term was made obsolete because it is a redundant grouping term.	GO:0015173|GO:0015171				True				molecular_function											owl:Class	
GO:0031029	biolink:NamedThing	regulation of septation initiation signaling	Any process that modulates the frequency, rate or extent of septation initiation signaling.	got7fsn_ti	regulation of septation initiation signaling cascade|regulation of septation initiation signalling|regulation of septation initiation network													biological_process											owl:Class	
GO:1904215	biolink:NamedThing	regulation of protein import into chloroplast stroma	Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma.	got7fsn_ti	regulation of chloroplast stroma protein import|regulation of protein transport into chloroplast stroma						tb	2015-05-15T00:47:48Z						biological_process											owl:Class	
GO:1901326	biolink:NamedThing	response to tetracycline	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.	got7fsn_ti							mah	2012-08-30T10:13:26Z						biological_process											owl:Class	
GO:0140135	biolink:NamedThing	mechanosensitive cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens in response to a mechanical stress.	got7fsn_ti	mechanically-gated cation channel activity	https://github.com/geneontology/go-ontology/issues/14588					pg	2017-11-17T12:40:37Z						molecular_function											owl:Class	
GO:0038040	biolink:NamedThing	obsolete cross-receptor activation within G-protein coupled receptor heterodimer	OBSOLETE. Activation of one protomer of a consequence of a G protein-coupled (GPCR) heterodimer by the associated subunit. For example, agonist occupancy in one protomer of a GPCR dimer may activate the associated promoter.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15823			This term was obsoleted because it should be captured as a GO-CAM model.		bf	2011-11-02T04:50:22Z		True				biological_process											owl:Class	
GO:1900897	biolink:NamedThing	negative regulation of heptadecane biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process.	got7fsn_ti	inhibition of heptadecane biosynthetic process|down-regulation of heptadecane synthesis|down regulation of heptadecane anabolism|inhibition of heptadecane formation|downregulation of heptadecane biosynthetic process|downregulation of heptadecane biosynthesis|down-regulation of heptadecane formation|downregulation of heptadecane anabolism|down regulation of heptadecane biosynthesis|negative regulation of heptadecane biosynthesis|down-regulation of heptadecane biosynthetic process|inhibition of heptadecane synthesis|negative regulation of heptadecane formation|downregulation of heptadecane formation|down regulation of heptadecane synthesis|negative regulation of heptadecane anabolism|negative regulation of heptadecane synthesis|down regulation of heptadecane biosynthetic process|inhibition of heptadecane anabolism|inhibition of heptadecane biosynthesis|down-regulation of heptadecane biosynthesis|downregulation of heptadecane synthesis|down-regulation of heptadecane anabolism|down regulation of heptadecane formation						tt	2012-06-13T03:28:02Z						biological_process											owl:Class	
GO:0008539	biolink:NamedThing	obsolete proteasome inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.	got7fsn_ti	PI-31|proteasome inhibitor activity				The term was made obsolete because 'proteasome' is not a valid molecular function term.	GO:0061136|GO:0004866				True				molecular_function											owl:Class	
GO:0006000	biolink:NamedThing	fructose metabolic process	The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.	got7fsn_ti	fructose metabolism											Wikipedia:Fructose		biological_process											owl:Class	
GO:1903493	biolink:NamedThing	response to clopidogrel	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.	got7fsn_ti							hp	2014-09-25T11:36:42Z						biological_process											owl:Class	
GO:0140157	biolink:NamedThing	ammonium import across plasma membrane	The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-01-26T12:39:56Z						biological_process											owl:Class	
GO:1904930	biolink:NamedThing	amphisome membrane	Any membrane that is part of an amphisome.	got7fsn_ti							pr	2016-01-29T11:40:13Z						cellular_component											owl:Class	
GO:0045769	biolink:NamedThing	negative regulation of asymmetric cell division	Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.	got7fsn_ti	inhibition of asymmetric cell division|down-regulation of asymmetric cell division|down regulation of asymmetric cell division|downregulation of asymmetric cell division													biological_process											owl:Class	
GO:2000916	biolink:NamedThing	negative regulation of glucuronoxylan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process.	got7fsn_ti	negative regulation of glucuronoxylan catabolism						tt	2011-07-29T07:54:44Z						biological_process											owl:Class	
GO:0060860	biolink:NamedThing	regulation of floral organ abscission	Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.	got7fsn_ti							dph	2009-08-12T03:59:45Z						biological_process											owl:Class	
GO:0071644	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 4 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.	got7fsn_ti	negative regulation of MIP-1b production|negative regulation of macrophage inflammatory protein production|negative regulation of CCL4 production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:0036039	biolink:NamedThing	curcumin metabolic process	The chemical reactions and pathways involving the polyphenol, curcumin.	got7fsn_ti	turmeric yellow metabolism|diferuloylmethane metabolic process|curcumin metabolism|diferuloylmethane metabolism|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism|turmeric yellow metabolic process						bf	2011-11-22T01:58:57Z						biological_process											owl:Class	
GO:1903234	biolink:NamedThing	negative regulation of calcium ion-dependent exocytosis of neurotransmitter	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.	got7fsn_ti	down-regulation of calcium ion-dependent exocytosis of neurotransmitter|down regulation of calcium ion-dependent exocytosis of neurotransmitter|downregulation of calcium ion-dependent exocytosis of neurotransmitter|inhibition of calcium ion-dependent exocytosis of neurotransmitter				An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP)		pad	2014-07-31T11:54:40Z						biological_process											owl:Class	
GO:0042691	biolink:NamedThing	positive regulation of crystal cell differentiation	Any process that activates or increases the frequency, rate or extent of crystal cell differentiation.	got7fsn_ti	stimulation of crystal cell differentiation|activation of crystal cell differentiation|up-regulation of crystal cell differentiation|up regulation of crystal cell differentiation|upregulation of crystal cell differentiation													biological_process											owl:Class	
GO:0046168	biolink:NamedThing	glycerol-3-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.	got7fsn_ti	glycerol-3-phosphate degradation|glycerol-3-phosphate breakdown|glycerol-3-phosphate catabolism													biological_process											owl:Class	
GO:0034213	biolink:NamedThing	quinolinate catabolic process	The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.	got7fsn_ti	quinolinate catabolism|quinolinate degradation|quinolinate breakdown													biological_process											owl:Class	
GO:0019483	biolink:NamedThing	beta-alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.	got7fsn_ti	beta-alanine synthesis|beta-alanine anabolism|beta-alanine formation|beta-alanine biosynthesis													biological_process											owl:Class	
GO:0006535	biolink:NamedThing	cysteine biosynthetic process from serine	The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.	got7fsn_ti	cysteine anabolism from serine|cysteine synthesis from serine|cysteine formation from serine											MetaCyc:CYSTSYN-PWY		biological_process											owl:Class	
GO:0002886	biolink:NamedThing	regulation of myeloid leukocyte mediated immunity	Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.	got7fsn_ti														biological_process											owl:Class	
GO:0093001	biolink:NamedThing	glycolysis from storage polysaccharide through glucose-1-phosphate	The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.	got7fsn_ti														biological_process											owl:Class	
GO:0046514	biolink:NamedThing	ceramide catabolic process	The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.	got7fsn_ti	ceramide degradation|ceramide breakdown|ceramide catabolism													biological_process											owl:Class	
GO:1901762	biolink:NamedThing	oxytetracycline catabolic process	The chemical reactions and pathways resulting in the breakdown of oxytetracycline.	got7fsn_ti	oxytetracycline degradation|oxytetracycline catabolism|oxytetracycline breakdown						yaf	2013-01-15T09:52:55Z						biological_process											owl:Class	
GO:1903453	biolink:NamedThing	obsolete RNA interference involved in olfactory learning	OBSOLETE. Any RNA interference that is involved in olfactory learning.	got7fsn_ti	RNAi involved in olfactory learning|posttranscriptional gene silencing by siRNA involved in olfactory learning	https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.		kmv	2014-09-22T13:50:09Z		True				biological_process											owl:Class	
GO:0016130	biolink:NamedThing	phytosteroid catabolic process	The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.	got7fsn_ti	phytosteroid degradation|phytosteroid breakdown|phytosteroid catabolism													biological_process											owl:Class	
GO:1905945	biolink:NamedThing	regulation of response to calcium ion	Any process that modulates the frequency, rate or extent of response to calcium ion.	got7fsn_ti	regulation of response to Ca2+ ion						bc	2017-02-13T10:56:34Z						biological_process											owl:Class	
GO:0009614	biolink:NamedThing	obsolete disease resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	disease resistance			GO:0051707	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0051413	biolink:NamedThing	response to cortisone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.	got7fsn_ti	response to cortisone stimulus													biological_process											owl:Class	
GO:2000814	biolink:NamedThing	positive regulation of barbed-end actin filament capping	Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.	got7fsn_ti	positive regulation of barbed-end actin capping activity|positive regulation of plus-end F-actin capping activity|positive regulation of plus-end actin filament capping activity|positive regulation of barbed-end F-actin capping activity						rl	2011-07-07T04:08:23Z						biological_process											owl:Class	
GO:0002841	biolink:NamedThing	negative regulation of T cell mediated immune response to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell.	got7fsn_ti	inhibition of T cell mediated immune response to tumor cell|negative regulation of T cell mediated immune response to tumour cell|negative regulation of T-cell mediated immune response to tumor cell|downregulation of T cell mediated immune response to tumor cell|negative regulation of T lymphocyte mediated immune response to tumor cell|negative regulation of T-lymphocyte mediated immune response to tumor cell|down regulation of T cell mediated immune response to tumor cell|down-regulation of T cell mediated immune response to tumor cell													biological_process											owl:Class	
GO:0048070	biolink:NamedThing	regulation of developmental pigmentation	Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.	got7fsn_ti	regulation of pigmentation during development													biological_process											owl:Class	
GO:0044258	biolink:NamedThing	intestinal lipid catabolic process	The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.	got7fsn_ti	intestinal lipid breakdown|intestinal lipid catabolism|intestinal lipid degradation													biological_process											owl:Class	
GO:0046105	biolink:NamedThing	thymidine biosynthetic process	The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.	got7fsn_ti	thymidine synthesis|deoxyribosylthymine biosynthesis|thymidine biosynthesis|deoxyribosylthymine biosynthetic process|thymidine anabolism|thymidine formation													biological_process											owl:Class	
GO:1903786	biolink:NamedThing	regulation of glutathione biosynthetic process	Any process that modulates the frequency, rate or extent of glutathione biosynthetic process.	got7fsn_ti	regulation of glutathione biosynthesis|regulation of glutathione formation|regulation of glutathione anabolism|regulation of glutathione synthesis						bf	2015-01-08T17:14:49Z						biological_process											owl:Class	
GO:0034374	biolink:NamedThing	low-density lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.	got7fsn_ti	small dense LDL formation|small dense low-density lipoprotein particle formation|LDL remodeling													biological_process											owl:Class	
GO:0000989	biolink:NamedThing	obsolete transcription factor activity, transcription factor binding	OBSOLETE. Binding to a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	transcription factor binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0008134|GO:0140110	krc	2010-08-10T04:57:43Z		True				molecular_function											owl:Class	
GO:0009195	biolink:NamedThing	pyrimidine ribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside diphosphate breakdown|pyrimidine ribonucleoside diphosphate catabolism|pyrimidine ribonucleoside diphosphate degradation													biological_process											owl:Class	
GO:0002849	biolink:NamedThing	regulation of peripheral T cell tolerance induction	Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.	got7fsn_ti														biological_process											owl:Class	
GO:1900267	biolink:NamedThing	positive regulation of substance P receptor binding	Any process that activates or increases the frequency, rate or extent of substance P receptor binding.	got7fsn_ti	upregulation of substance P receptor ligand|upregulation of substance P receptor binding|activation of substance P receptor binding|positive regulation of neurokinin-1 receptor binding|upregulation of neurokinin-1 receptor binding|positive regulation of substance P receptor ligand|activation of substance P receptor ligand|up regulation of substance P receptor ligand|up-regulation of substance P receptor ligand|up regulation of neurokinin-1 receptor binding|up regulation of substance P receptor binding|activation of neurokinin-1 receptor binding|up-regulation of neurokinin-1 receptor binding|up-regulation of substance P receptor binding						tb	2012-04-03T11:11:45Z						biological_process											owl:Class	
GO:0046609	biolink:NamedThing	obsolete voltage-gated sulfate antiporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + solute(in) = solute(in) + sulfate(out), by a channel in a cell membrane whose opening is governed by the membrane potential.	got7fsn_ti	voltage-sensitive sulfate antiporter activity|voltage-dependent sulfate antiporter activity|voltage gated sulfate antiporter activity|voltage-sensitive sulphate antiporter activity|prestin				This term was obsoleted because there is no evidence that this function exists.					True				molecular_function											owl:Class	
GO:1900829	biolink:NamedThing	D-tyrosine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-tyrosine.	got7fsn_ti	D-tyrosine breakdown|D-tyrosine catabolism|D-tyrosine degradation						se	2012-06-06T09:27:24Z						biological_process											owl:Class	
GO:0048238	biolink:NamedThing	smooth endoplasmic reticulum lumen	The volume enclosed by the membranes of the smooth endoplasmic reticulum.	got7fsn_ti	smooth ER lumen|SER lumen											NIF_Subcellular:sao927884761		cellular_component											owl:Class	
GO:0048022	biolink:NamedThing	negative regulation of melanin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.	got7fsn_ti	inhibition of melanin biosynthetic process|negative regulation of melanin anabolism|down regulation of melanin biosynthetic process|negative regulation of melanin synthesis|negative regulation of melanin formation|downregulation of melanin biosynthetic process|down-regulation of melanin biosynthetic process|negative regulation of melanin biosynthesis													biological_process											owl:Class	
GO:0009109	biolink:NamedThing	obsolete coenzyme catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	got7fsn_ti	coenzyme breakdown|coenzyme and prosthetic group catabolism|coenzyme catabolism|coenzyme degradation|coenzyme and prosthetic group catabolic process				1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group catabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True				biological_process											owl:Class	
GO:0052114	biolink:NamedThing	obsolete adaptation to host pH environment	OBSOLETE. The responsive adjustment of an organism to the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	adaptation to host pH environment|pH tolerance to host environment				This term was made obsolete because adaptation was not deemed to be a valid biological process.					True				biological_process											owl:Class	
GO:0061993	biolink:NamedThing	calcium:proton antiporter complex	A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).	got7fsn_ti	CAX1 homodimer|CAX3 homodimer|CAX1-CAX3 complex						dph	2018-02-16T02:17:10Z						cellular_component											owl:Class	
GO:0090283	biolink:NamedThing	regulation of protein glycosylation in Golgi	Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.	got7fsn_ti	regulation of protein amino acid glycosylation in Golgi						tb	2010-02-18T02:43:55Z						biological_process											owl:Class	
GO:0072730	biolink:NamedThing	response to papulacandin B	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.	got7fsn_ti							mah	2012-05-31T11:30:32Z						biological_process											owl:Class	
GO:1905541	biolink:NamedThing	regulation of L-arginine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane.	got7fsn_ti	regulation of L-arginine import into cell							2014-03-31T14:30:40Z			GO:1902826			biological_process											owl:Class	
GO:0033347	biolink:NamedThing	tetrose metabolic process	The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.	got7fsn_ti	tetrose metabolism													biological_process											owl:Class	
GO:0072460	biolink:NamedThing	obsolete detection of stimulus involved in meiotic recombination checkpoint	OBSOLETE. The series of events in which information about whether recombination is complete is received and converted into a molecular signal, contributing to a meiotic recombination checkpoint.	got7fsn_ti	meiotic recombination checkpoint sensor mechanism|meiotic recombination checkpoint sensor process|sensing involved in meiotic recombination checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:36:42Z		True				biological_process											owl:Class	
GO:0039558	biolink:NamedThing	obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 sumoylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF7-dependent gene transcription, by promoting the sumoylation of IRF7, thereby disabling its activity.	got7fsn_ti	promotion of IRF-7 SUMOylation|suppression by virus of host interferon regulatory factor-7 activity by positive regulation of IRF7 sumoylation				The reason for obsoleting is that the term is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-09T04:27:57Z		True				biological_process											owl:Class	
GO:0015034	biolink:NamedThing	obsolete cytochrome P450 activity	OBSOLETE. A cytochrome b-like protein that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes: typically monooxygenases acting on, typically, lipophilic substrates. The characteristic mode of action of these enzymes is not electron transfer (some P450 enzymes probably do not even involve the reversible Fe(II)/Fe(III) equilibrium), but rather oxygen atom transfer.	got7fsn_ti	cytochrome P450 activity				This term was made obsolete because it is a grouping term representing a set of gene products.	GO:0019825				True				molecular_function											owl:Class	
GO:1902266	biolink:NamedThing	cellular abscisic acid homeostasis	Any biological process involved in the maintenance of an internal steady state of abscisic acid at the level of the cell.	got7fsn_ti	cellular ABA homeostasis|cellular 2-cis-abscisate homeostasis						tb	2013-06-27T21:05:36Z						biological_process											owl:Class	
GO:1900544	biolink:NamedThing	positive regulation of purine nucleotide metabolic process	Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.	got7fsn_ti	up-regulation of purine metabolic process|positive regulation of purine metabolism|activation of purine nucleotide metabolism|upregulation of purine metabolism|up-regulation of purine nucleotide metabolic process|activation of purine metabolism|up regulation of purine metabolism|up-regulation of purine nucleotide metabolism|upregulation of purine metabolic process|activation of purine metabolic process|up-regulation of purine metabolism|up regulation of purine metabolic process|positive regulation of purine nucleotide metabolism|up regulation of purine nucleotide metabolism|activation of purine nucleotide metabolic process|upregulation of purine nucleotide metabolic process|positive regulation of purine metabolic process|up regulation of purine nucleotide metabolic process|upregulation of purine nucleotide metabolism						krc	2012-05-11T05:44:43Z						biological_process											owl:Class	
GO:0046300	biolink:NamedThing	2,4-dichlorophenoxyacetic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.	got7fsn_ti	2,4-dichlorophenoxyacetic acid breakdown|2,4-dichlorophenoxyacetic acid catabolism|2,4-dichlorophenoxyacetic acid degradation													biological_process											owl:Class	
GO:0014804	biolink:NamedThing	terminal cisterna lumen	The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin.	got7fsn_ti														cellular_component											owl:Class	
GO:1900311	biolink:NamedThing	positive regulation of maltoheptaose metabolic process	Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process.	got7fsn_ti	upregulation of maltoheptaose metabolism|activation of maltoheptaose metabolic process|up-regulation of maltoheptaose metabolic process|activation of maltoheptaose metabolism|up regulation of maltoheptaose metabolic process|positive regulation of maltoheptaose metabolism|upregulation of maltoheptaose metabolic process|up regulation of maltoheptaose metabolism|up-regulation of maltoheptaose metabolism						tt	2012-04-05T07:59:06Z						biological_process											owl:Class	
GO:1905223	biolink:NamedThing	epicardium morphogenesis	The developmental process by which an epicardium is generated and organized.	got7fsn_ti	pericardium visceral mesothelium morphogenesis|visceral serous pericardium proper morphogenesis|heart epicardium morphogenesis|visceral serous pericardium of heart morphogenesis						rl	2016-06-07T10:02:32Z						biological_process											owl:Class	
GO:0005617	biolink:NamedThing	obsolete larval serum protein-1	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	larval serum protein-1|LSP1				This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
GO:0006125	biolink:NamedThing	obsolete thioredoxin pathway	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	thioredoxin pathway|thioredoxin reduction				This term was made obsolete because it is not clear what it is intended to represent.	GO:0045454				True		MetaCyc:THIOREDOX-PWY		biological_process											owl:Class	
GO:1901300	biolink:NamedThing	positive regulation of hydrogen peroxide-mediated programmed cell death	Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.	got7fsn_ti	up regulation of hydrogen peroxide-mediated programmed cell death|upregulation of hydrogen peroxide-mediated programmed cell death|up-regulation of hydrogen peroxide-mediated programmed cell death|activation of hydrogen peroxide-mediated programmed cell death						vk	2012-08-21T09:45:29Z						biological_process											owl:Class	
UBERON:0002384	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000840	biolink:NamedThing	regulation of dehydroepiandrosterone secretion	Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion.	got7fsn_ti	regulation of dehydroisoandrosterone secretion|regulation of 3beta-hydroxyandrost-5-en-17-one secretion|regulation of DHEA secretion						bf	2011-07-26T08:41:29Z						biological_process											owl:Class	
GO:1900528	biolink:NamedThing	obsolete regulation of cell shape involved in G1 to G0 transition	OBSOLETE. Any regulation of cell shape that is involved in G1 to G0 transition.	got7fsn_ti	regulation of cell shape involved in stationary phase|regulation of cell shape involved in cell cycle quiescence|regulation of cell shape involved in G1 to G0 transition|regulation of cell shape involved in establishment of cell quiescence|regulation of cell shape involved in G1/G0 transition				This term was made obsolete because it represents a phenotype.		al	2012-05-08T10:42:45Z		True				biological_process											owl:Class	
CHEBI:17540	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0006001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043498	biolink:NamedThing	obsolete cell surface binding	OBSOLETE. Binding to a component on the surface of a cell.	got7fsn_ti	cell surface binding				This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term.	GO:0009986|GO:0005102|GO:0046812|GO:0003823|GO:0007155				True				molecular_function											owl:Class	
GO:0045906	biolink:NamedThing	negative regulation of vasoconstriction	Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.	got7fsn_ti	down regulation of vasoconstriction|down-regulation of vasoconstriction|downregulation of vasoconstriction|inhibition of vasoconstriction													biological_process											owl:Class	
GO:2000274	biolink:NamedThing	regulation of epithelial cell migration, open tracheal system	Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system.	got7fsn_ti	regulation of tracheal epithelial cell migration|regulation of tracheal cell migration						sart	2010-12-03T02:08:43Z						biological_process											owl:Class	
GO:1905772	biolink:NamedThing	positive regulation of mesodermal cell differentiation	Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation.	got7fsn_ti	up regulation of mesoderm cell differentiation|up regulation of mesodermal cell differentiation|activation of mesoderm cell differentiation|activation of mesodermal cell differentiation|positive regulation of mesoderm cell differentiation|up-regulation of mesoderm cell differentiation|upregulation of mesodermal cell differentiation|up-regulation of mesodermal cell differentiation|upregulation of mesoderm cell differentiation						rph	2016-12-21T12:44:32Z						biological_process											owl:Class	
GO:0002608	biolink:NamedThing	negative regulation of myeloid dendritic cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.	got7fsn_ti	down-regulation of myeloid dendritic cell antigen processing and presentation|down regulation of myeloid dendritic cell antigen processing and presentation|downregulation of myeloid dendritic cell antigen processing and presentation|inhibition of myeloid dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0071307	biolink:NamedThing	cellular response to vitamin K	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.	got7fsn_ti							mah	2009-12-10T04:36:09Z						biological_process											owl:Class	
GO:0050814	biolink:NamedThing	epothilone biosynthetic process	The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.	got7fsn_ti	epothilone biosynthesis|epothilone anabolism|epothilone formation|epothilone synthesis													biological_process											owl:Class	
GO:1902123	biolink:NamedThing	(-)-pinoresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol.	got7fsn_ti	(-)-pinoresinol breakdown|(-)-pinoresinol degradation|(-)-pinoresinol catabolism						ms	2013-05-21T08:49:05Z						biological_process											owl:Class	
GO:0050859	biolink:NamedThing	negative regulation of B cell receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.	got7fsn_ti	negative regulation of B-cell receptor signalling pathway|negative regulation of B cell receptor signalling pathway|inhibition of B cell receptor signaling pathway|down-regulation of B cell receptor signaling pathway|negative regulation of B-cell receptor signaling pathway|negative regulation of B-lymphocyte receptor signalling pathway|negative regulation of B lymphocyte receptor signaling pathway|negative regulation of B lymphocyte receptor signalling pathway|down regulation of B cell receptor signaling pathway|downregulation of B cell receptor signaling pathway|negative regulation of B-lymphocyte receptor signaling pathway													biological_process											owl:Class	
GO:0010936	biolink:NamedThing	negative regulation of macrophage cytokine production	Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti														biological_process											owl:Class	
GO:1900623	biolink:NamedThing	regulation of monocyte aggregation	Any process that modulates the frequency, rate or extent of monocyte aggregation.	got7fsn_ti	regulation of mononuclear phagocyte aggregation						vk	2012-05-21T01:07:17Z						biological_process											owl:Class	
GO:0043301	biolink:NamedThing	negative regulation of leukocyte degranulation	Any process that stops, prevents, or reduces the rate of leukocyte degranulation.	got7fsn_ti	negative regulation of immune cell degranulation|negative regulation of leucocyte degranulation|down-regulation of leukocyte degranulation|downregulation of leukocyte degranulation|inhibition of leukocyte degranulation|down regulation of leukocyte degranulation													biological_process											owl:Class	
GO:1902292	biolink:NamedThing	cell cycle DNA replication initiation	Any DNA replication initiation that is involved in cell cycle DNA replication.	got7fsn_ti	DNA replication initiation involved in cell cycle DNA replication|DNA-dependent DNA replication initiation involved in cell cycle DNA replication|DNA endoreduplication initiation involved in cell cycle DNA replication|DNA re-replication initiation involved in cell cycle DNA replication						jl	2013-07-09T16:05:54Z						biological_process											owl:Class	
GO:1904013	biolink:NamedThing	obsolete xenon atom binding	OBSOLETE. Binding to xenon atom.	got7fsn_ti					The reason for obsoletion is that binding to xenon does not have physiological relevance.		sl	2015-03-06T19:07:43Z		True				molecular_function											owl:Class	
GO:1901868	biolink:NamedThing	ecgonine methyl ester catabolic process	The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester.	got7fsn_ti	ecgonine methyl ester degradation|ecgonine methyl ester breakdown|ecgonine methyl ester catabolism						ms	2013-02-04T11:58:18Z						biological_process											owl:Class	
GO:1904430	biolink:NamedThing	negative regulation of t-circle formation	Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.	got7fsn_ti	down regulation of t-circle formation|inhibition of t-circle formation|negative regulation of telomeric circle formation|downregulation of telomeric circle formation|downregulation of t-circle formation|down-regulation of telomeric circle formation|down-regulation of t-circle formation|down regulation of telomeric circle formation|inhibition of telomeric circle formation						nc	2015-07-03T15:15:52Z						biological_process											owl:Class	
GO:1902572	biolink:NamedThing	negative regulation of serine-type peptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity.	got7fsn_ti	down regulation of serine protease activity|down regulation of serine-type peptidase activity|downregulation of serine-type peptidase activity|inhibition of serine protease activity|downregulation of serine protease activity|down-regulation of serine protease activity|inhibition of serine-type peptidase activity|negative regulation of serine protease activity|down-regulation of serine-type peptidase activity						krc	2013-12-10T18:17:07Z						biological_process											owl:Class	
GO:0097026	biolink:NamedThing	dendritic cell dendrite assembly	Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.	got7fsn_ti	dendritic extension				Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals.		pr	2011-03-31T04:52:53Z						biological_process											owl:Class	
GO:1904004	biolink:NamedThing	positive regulation of sebum secreting cell proliferation	Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation.	got7fsn_ti	up regulation of sebum secreting cell proliferation|upregulation of sebocyte proliferation|up regulation of sebocyte proliferation|activation of sebum secreting cell proliferation|activation of sebocyte proliferation|up-regulation of sebocyte proliferation|positive regulation of sebocyte proliferation|up-regulation of sebum secreting cell proliferation|upregulation of sebum secreting cell proliferation						hjd	2015-03-06T16:19:56Z						biological_process											owl:Class	
GO:0039712	biolink:NamedThing	obsolete induction by virus of host catalytic activity	OBSOLETE. Any viral process that activates or increases the frequency, rate or extent of host catalytic activity.	got7fsn_ti	induction by virus of host enzyme activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.		bf	2013-12-19T13:21:45Z		True				biological_process											owl:Class	
CL:1000001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900786	biolink:NamedThing	naphtho-gamma-pyrone catabolic process	The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone.	got7fsn_ti	naphtho-gamma-pyrone catabolism|naphtho-gamma-pyrones catabolism|naphtho-gamma-pyrones breakdown|naphtho-gamma-pyrone degradation|naphtho-gamma-pyrones degradation|naphtho-gamma-pyrones catabolic process|naphtho-gamma-pyrone breakdown						di	2012-06-04T09:35:54Z						biological_process											owl:Class	
GO:0036111	biolink:NamedThing	very long-chain fatty-acyl-CoA metabolic process	The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	got7fsn_ti	very long-chain fatty acyl-CoA metabolism|very long-chain fatty acyl CoA metabolic process						bf	2012-02-15T11:09:22Z						biological_process											owl:Class	
GO:1904646	biolink:NamedThing	cellular response to amyloid-beta	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.	got7fsn_ti	cellular response to beta-amyloids|cellular response to beta-amyloid						sl	2015-08-31T20:44:49Z						biological_process											owl:Class	
GO:1904616	biolink:NamedThing	regulation of actin binding	Any process that modulates the frequency, rate or extent of actin binding.	got7fsn_ti	regulation of membrane associated actin binding						mr	2015-08-27T19:08:56Z						biological_process											owl:Class	
GO:1901087	biolink:NamedThing	benzylpenicillin catabolic process	The chemical reactions and pathways resulting in the breakdown of benzylpenicillin.	got7fsn_ti	penicillin G degradation|penicillin G catabolic process|benzylpenicillin degradation|penicillin G breakdown|penicillin G catabolism|benzylpenicillin catabolism|benzylpenicillin breakdown						yaf	2012-07-05T10:28:59Z						biological_process											owl:Class	
GO:0000060	biolink:NamedThing	obsolete protein import into nucleus, translocation	OBSOLETE. A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.	got7fsn_ti	protein translocation during protein transport from cytoplasm to nucleus|protein translocation during protein import into nucleus|protein-nucleus import, translocation|protein transport from cytoplasm to nucleus, translocation|protein import into cell nucleus, translocation|protein translocation during protein-nucleus import				This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True				biological_process											owl:Class	
GO:0007337	biolink:NamedThing	obsolete unilateral process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	unilateral process				This term was made obsolete because it gives no indication of what it refers to.					True				biological_process											owl:Class	
GO:1900196	biolink:NamedThing	regulation of penicillin biosynthetic process	Any process that modulates the frequency, rate or extent of penicillin biosynthetic process.	got7fsn_ti	regulation of penicillin synthesis|regulation of penicillin anabolism|regulation of penicillin biosynthesis|regulation of penicillin formation						di	2012-03-20T03:56:33Z						biological_process											owl:Class	
GO:0010645	biolink:NamedThing	regulation of cell communication by chemical coupling	Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti														biological_process											owl:Class	
GO:1901785	biolink:NamedThing	p-cresol catabolic process	The chemical reactions and pathways resulting in the breakdown of p-cresol.	got7fsn_ti	p-cresol catabolism|p-cresol breakdown|p-cresol degradation						yaf	2013-01-16T11:04:04Z						biological_process											owl:Class	
GO:0090419	biolink:NamedThing	negative regulation of transcription involved in G2/M transition of mitotic cell cycle	Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.	got7fsn_ti	down-regulation of transcription from RNA polymerase II promoter during the G2/M transition of the mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle						tb	2011-10-26T03:59:41Z						biological_process											owl:Class	
GO:2000337	biolink:NamedThing	positive regulation of endothelial microparticle formation	Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation.	got7fsn_ti	positive regulation of endothelial microparticle release|positive regulation of endothelial microparticle generation						mah	2011-01-31T11:20:38Z						biological_process											owl:Class	
GO:0042374	biolink:NamedThing	phylloquinone metabolic process	The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1.	got7fsn_ti	phylloquinone metabolism|phytomenadione metabolic process|vitamin K1 metabolic process|phytylmenaquinone metabolism|phytomenadione metabolism|vitamin K1 metabolism|phytonadione metabolic process|phytylmenaquinone metabolic process|phytonadione metabolism													biological_process											owl:Class	
GO:0002690	biolink:NamedThing	positive regulation of leukocyte chemotaxis	Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.	got7fsn_ti	upregulation of leukocyte chemotaxis|up-regulation of leukocyte chemotaxis|positive regulation of leucocyte chemotaxis|up regulation of leukocyte chemotaxis|positive regulation of immune cell chemotaxis|activation of leukocyte chemotaxis|stimulation of leukocyte chemotaxis													biological_process											owl:Class	
GO:0051556	biolink:NamedThing	leucoanthocyanidin metabolic process	The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.	got7fsn_ti	leucoanthocyanidin metabolism											MetaCyc:PWY1F-823		biological_process											owl:Class	
GO:0120175	biolink:NamedThing	regulation of torso signaling pathway	Any process that modulates the frequency, rate or extent of the torso signaling pathway.	got7fsn_ti							krc	2018-06-07T16:47:42Z						biological_process											owl:Class	
GO:1903116	biolink:NamedThing	positive regulation of actin filament-based movement	Any process that activates or increases the frequency, rate or extent of actin filament-based movement.	got7fsn_ti	activation of actin filament-based movement|up-regulation of actin filament-based movement|upregulation of actin filament-based movement|up regulation of actin filament-based movement						al	2014-06-12T16:56:04Z						biological_process											owl:Class	
GO:0060189	biolink:NamedThing	positive regulation of protein desumoylation	Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.	got7fsn_ti														biological_process											owl:Class	
GO:0071723	biolink:NamedThing	lipopeptide binding	Binding to a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids.	got7fsn_ti	bacterial lipoprotein binding|bacterial lipopeptide binding				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:13:21Z						molecular_function											owl:Class	
GO:1901249	biolink:NamedThing	regulation of lung goblet cell differentiation	Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.	got7fsn_ti	regulation of pulmonary goblet cell differentiation						vk	2012-08-08T08:59:12Z						biological_process											owl:Class	
GO:0033490	biolink:NamedThing	cholesterol biosynthetic process via lathosterol	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.	got7fsn_ti	cholesterol biosynthesis via lathosterol|cholesterol synthesis via lathosterol|cholesterol anabolism via lathosterol|cholesterol formation via lathosterol											MetaCyc:PWY66-341		biological_process											owl:Class	
GO:0051187	biolink:NamedThing	obsolete cofactor catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein.	got7fsn_ti	cofactor catabolism|cofactor degradation|cofactor breakdown				1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True				biological_process											owl:Class	
GO:1905857	biolink:NamedThing	positive regulation of pentose-phosphate shunt	Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt.	got7fsn_ti							vw	2017-01-23T14:00:26Z						biological_process											owl:Class	
GO:0019435	biolink:NamedThing	sophorosyloxydocosanoate biosynthetic process	The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.	got7fsn_ti	sophorosyloxydocosanoate anabolism|sophorosyloxydocosanoate synthesis|sophorosyloxydocosanoate biosynthesis|sophorosyloxydocosanoate formation											MetaCyc:SOPHOROSYLOXYDOCOSANOATE-SYN-PWY		biological_process											owl:Class	
GO:1901858	biolink:NamedThing	regulation of mitochondrial DNA metabolic process	Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.	got7fsn_ti	regulation of mtDNA metabolism|regulation of mitochondrial DNA metabolism|regulation of mtDNA metabolic process						yaf	2013-02-01T10:05:04Z						biological_process											owl:Class	
GO:1902934	biolink:NamedThing	isopentenol biosynthetic process	The chemical reactions and pathways resulting in the formation of isopentenol.	got7fsn_ti	isopentenol synthesis|isopentenol biosynthesis|isopentenol formation|isopentenol anabolism						tt	2014-04-24T16:51:42Z						biological_process											owl:Class	
GO:1902207	biolink:NamedThing	positive regulation of interleukin-2-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway.	got7fsn_ti	up regulation of interleukin-2-mediated signaling pathway|up-regulation of IL-2-mediated signaling pathway|up-regulation of interleukin-2-mediated signaling pathway|activation of interleukin-2-mediated signalling pathway|positive regulation of interleukin-2-mediated signalling pathway|upregulation of interleukin-2-mediated signalling pathway|upregulation of IL-2-mediated signaling pathway|activation of interleukin-2-mediated signaling pathway|upregulation of interleukin-2-mediated signaling pathway|up regulation of IL-2-mediated signaling pathway|positive regulation of IL-2-mediated signaling pathway|activation of IL-2-mediated signaling pathway|up-regulation of interleukin-2-mediated signalling pathway|up regulation of interleukin-2-mediated signalling pathway						lb	2013-06-11T07:34:50Z						biological_process											owl:Class	
GO:0070395	biolink:NamedThing	lipoteichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	got7fsn_ti	lipoteichoic acid formation|LTA biosynthetic process|lipoteichoic acid biosynthesis|lipoteichoic acid anabolism|lipoteichoic acid synthesis													biological_process											owl:Class	
GO:0010121	biolink:NamedThing	arginine catabolic process to proline via ornithine	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine.	got7fsn_ti	arginine degradation to proline via ornithine|arginine breakdown to proline via ornithine											MetaCyc:ARGORNPROST-PWY		biological_process											owl:Class	
GO:0060826	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern.	got7fsn_ti	transforming growth factor beta receptor signalling pathway involved in neural plate anterior/posterior pattern formation						dph	2009-08-11T01:43:29Z						biological_process											owl:Class	
GO:0044434	biolink:NamedThing	obsolete chloroplast part	OBSOLETE. Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009507				True				cellular_component											owl:Class	
GO:1990800	biolink:NamedThing	obsolete meiotic APC-fizzy-related complex	OBSOLETE. An anaphase promoting complex bound to a fizzy-related family APC activator that regulates meiotic exit by activating the APC/C to target meiotic cyclins for destruction during meiosis.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-07-16T10:37:05Z		True				cellular_component											owl:Class	
GO:0071835	biolink:NamedThing	mating pheromone secretion involved in regulation of conjugation	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.	got7fsn_ti	mating-type pheromone secretion involved in conjugation						mah	2010-09-09T11:23:19Z						biological_process											owl:Class	
GO:0000192	biolink:NamedThing	obsolete activation of MAPKK (pseudohyphal growth)	OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth.	got7fsn_ti	activation of MAPKK (pseudohyphal growth)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:1905488	biolink:NamedThing	positive regulation of anterior/posterior axon guidance	Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance.	got7fsn_ti	activation of anterior/posterior axon pathfinding|positive regulation of anterior/posterior axon pathfinding|up regulation of anterior/posterior axon pathfinding|up-regulation of anterior/posterior axon guidance|up regulation of anterior-posterior axon guidance|up regulation of anterior/posterior axon guidance|activation of anterior-posterior axon guidance|activation of anterior/posterior axon guidance|up-regulation of anterior/posterior axon pathfinding|up-regulation of anterior-posterior axon guidance|upregulation of anterior/posterior axon pathfinding|upregulation of anterior/posterior axon guidance|positive regulation of anterior-posterior axon guidance|upregulation of anterior-posterior axon guidance						hbye	2016-09-23T13:18:48Z						biological_process											owl:Class	
GO:0071615	biolink:NamedThing	obsolete oxidative deethylation	OBSOLETE. The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20250			This term was obsoleted because it represents a molecular function.		mah	2010-02-05T06:11:41Z		True				biological_process											owl:Class	
GO:0021805	biolink:NamedThing	cell movement involved in somal translocation	The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface.	got7fsn_ti	cell motility involved in somal translocation													biological_process											owl:Class	
GO:2000775	biolink:NamedThing	histone H3-S10 phosphorylation involved in chromosome condensation	Any histone H3-S10 phosphorylation that is involved in chromosome condensation.	got7fsn_ti	histone H3-S10 phosphorylation of chromosome condensation|histone H3S10 phosphorylation of chromosome condensation|histone H3 phosphorylation at S10 of chromosome condensation						mah	2011-06-22T03:58:00Z						biological_process											owl:Class	
GO:1900409	biolink:NamedThing	positive regulation of cellular response to oxidative stress	Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress.	got7fsn_ti	up-regulation of adaptive response to oxidative stress|upregulation of cellular response to oxidative stress|upregulation of adaptive response to oxidative stress|positive regulation of adaptive response to oxidative stress|up-regulation of cellular response to oxidative stress|activation of cellular response to oxidative stress|up regulation of cellular response to oxidative stress|up regulation of adaptive response to oxidative stress|activation of adaptive response to oxidative stress						mah	2012-04-20T03:31:16Z						biological_process											owl:Class	
GO:1903678	biolink:NamedThing	negative regulation of cap-independent translational initiation	Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation.	got7fsn_ti	inhibition of cap-independent translational initiation|down regulation of cap-independent translational initiation|down-regulation of cap-independent translational initiation|downregulation of cap-independent translational initiation						bf	2014-11-27T19:52:28Z						biological_process											owl:Class	
GO:0007401	biolink:NamedThing	obsolete pan-neural process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	pan-neural process				This term was made obsolete because its meaning is ambiguous.	GO:0007399|GO:0050877				True				biological_process											owl:Class	
GO:0002169	biolink:NamedThing	3-methylcrotonyl-CoA carboxylase complex, mitochondrial	A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.	got7fsn_ti	mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme|mitochondrial MCCC complex|mitochondrial methylcrotonoyl-CoA carboxylase complex						hjd	2010-03-15T04:58:08Z						cellular_component											owl:Class	
GO:0000300	biolink:NamedThing	obsolete peripheral to membrane of membrane fraction	OBSOLETE. Peripheral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; can be extracted from membrane fraction with high concentrations of salt or high pH.	got7fsn_ti	peripheral to membrane of membrane fraction				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0019898				True				cellular_component											owl:Class	
GO:1901156	biolink:NamedThing	neomycin metabolic process	The chemical reactions and pathways involving neomycin.	got7fsn_ti	neomycin metabolism						yaf	2012-07-17T04:27:57Z						biological_process											owl:Class	
GO:0032657	biolink:NamedThing	regulation of interleukin-14 production	Any process that modulates the frequency, rate, or extent of interleukin-14 production.	got7fsn_ti	regulation of interleukin-14 biosynthetic process|regulation of IL-14 production										GO:0045369			biological_process											owl:Class	
GO:0010513	biolink:NamedThing	positive regulation of phosphatidylinositol biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.	got7fsn_ti														biological_process											owl:Class	
GO:0045591	biolink:NamedThing	positive regulation of regulatory T cell differentiation	Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.	got7fsn_ti	positive regulation of regulatory T lymphocyte differentiation|positive regulation of regulatory T cell development|stimulation of regulatory T cell differentiation|positive regulation of suppressor T cell differentiation|positive regulation of suppressor T-cell differentiation|positive regulation of regulatory T-cell differentiation|up regulation of regulatory T cell differentiation|up-regulation of regulatory T cell differentiation|activation of regulatory T cell differentiation|upregulation of regulatory T cell differentiation|positive regulation of regulatory T-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0044144	biolink:NamedThing	obsolete modulation of growth of symbiont involved in interaction with host	OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.	got7fsn_ti	modulation of growth of symbiont during interaction with host				This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-06T01:56:48Z		True				biological_process											owl:Class	
GO:0003198	biolink:NamedThing	epithelial to mesenchymal transition involved in endocardial cushion formation	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.	got7fsn_ti							dph	2009-10-08T01:27:42Z						biological_process											owl:Class	
GO:1900424	biolink:NamedThing	regulation of defense response to bacterium	Any process that modulates the frequency, rate or extent of defense response to bacterium.	got7fsn_ti	regulation of defence response to bacteria|regulation of resistance response to pathogenic bacterium|regulation of defence response to pathogenic bacterium, incompatible interaction|regulation of defense response to bacteria|regulation of defence response to bacterium, incompatible interaction|regulation of defence response to pathogenic bacteria, incompatible interaction|regulation of antibacterial peptide activity|regulation of defence response to bacterium|regulation of defense response to bacterium, incompatible interaction|regulation of resistance response to pathogenic bacteria						dhl	2012-04-24T10:12:43Z			GO:1902477			biological_process											owl:Class	
GO:1900313	biolink:NamedThing	negative regulation of maltohexaose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport.	got7fsn_ti	inhibition of maltohexaose transport|downregulation of maltohexaose transport|down-regulation of maltohexaose transport|down regulation of maltohexaose transport						tt	2012-04-05T07:59:26Z						biological_process											owl:Class	
GO:0005565	biolink:NamedThing	obsolete mitochondrial tRNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	mitochondrial tRNA				Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0016480	biolink:NamedThing	negative regulation of transcription by RNA polymerase III	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.	got7fsn_ti	down-regulation of transcription from RNA polymerase III promoter|negative regulation of transcription from RNA polymerase III promoter|down regulation of transcription from RNA polymerase III promoter|inhibition of transcription from RNA polymerase III promoter|negative regulation of transcription from Pol III promoter|downregulation of transcription from RNA polymerase III promoter													biological_process											owl:Class	
GO:0090357	biolink:NamedThing	regulation of tryptophan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.	got7fsn_ti	regulation of tryptophan metabolism						tb	2010-06-29T02:38:48Z						biological_process											owl:Class	
GO:0071536	biolink:NamedThing	obsolete RING-like zinc finger domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RING-like zinc finger domain interaction.	got7fsn_ti	RING-like domain-mediated complex assembly				This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T03:19:47Z		True				biological_process											owl:Class	
GO:1900708	biolink:NamedThing	negative regulation of tensidol A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process.	got7fsn_ti	inhibition of tensidol A anabolism|down-regulation of tensidol A biosynthesis|negative regulation of tensidol A formation|down-regulation of tensidol A synthesis|down-regulation of tensidol A biosynthetic process|negative regulation of tensidol A anabolism|downregulation of tensidol A anabolism|down regulation of tensidol A synthesis|inhibition of tensidol A biosynthetic process|down regulation of tensidol A biosynthetic process|negative regulation of tensidol A biosynthesis|down regulation of tensidol A formation|inhibition of tensidol A formation|downregulation of tensidol A biosynthetic process|negative regulation of tensidol A synthesis|inhibition of tensidol A synthesis|inhibition of tensidol A biosynthesis|downregulation of tensidol A synthesis|down regulation of tensidol A biosynthesis|downregulation of tensidol A formation|down-regulation of tensidol A formation|down-regulation of tensidol A anabolism|downregulation of tensidol A biosynthesis|down regulation of tensidol A anabolism						di	2012-05-22T05:02:04Z						biological_process											owl:Class	
GO:0019018	biolink:NamedThing	obsolete bipartite viral genome	OBSOLETE. A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:1901968	biolink:NamedThing	regulation of polynucleotide 3'-phosphatase activity	Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity.	got7fsn_ti	regulation of DNA 3'-phosphatase activity|regulation of polynucleotide 3'-phosphohydrolase activity|regulation of deoxyribonucleate 3'-phosphatase activity|regulation of 2'(3')-polynucleotidase activity|regulation of 5'-polynucleotidekinase 3'-phosphatase activity						tb	2013-02-22T00:58:17Z						biological_process											owl:Class	
GO:2001283	biolink:NamedThing	Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell	Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus.	got7fsn_ti	Roundabout signalling pathway involved in muscle cell chemotaxis towards tendon cell|Roundabout signalling pathway involved in muscle cell chemotaxis toward tendon cell|ROBO signaling pathway involved in muscle cell chemotaxis toward tendon cell|ROBO signaling pathway involved in muscle cell chemotaxis towards tendon cell|Roundabout signalling pathway involved in muscle cell attraction|Roundabout signaling pathway involved in muscle cell attraction|ROBO/SLIT signaling pathway involved in muscle cell chemotaxis towards tendon cell|ROBO signaling pathway involved in muscle cell attraction|ROBO/SLIT signaling pathway involved in muscle cell chemotaxis toward tendon cell|Roundabout signaling pathway involved in muscle cell chemotaxis towards tendon cell|ROBO/SLIT signaling pathway involved in muscle cell attraction						bf	2011-12-15T10:42:03Z						biological_process											owl:Class	
GO:0003816	biolink:NamedThing	obsolete complement component C1s activity	OBSOLETE. Catalysis of the cleavage of component C4 to C4a and C4b (Arg-Ala bond), and component C2 to C2a and C2b (Lys-Lys or Arg-Lys bond).	got7fsn_ti	complement C1s|C1s esterase activity|complement subcomponent C1s|activated complement C1s|C1 esterase activity|complement component C1s activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0000094	biolink:NamedThing	obsolete septin assembly and septum formation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	septin assembly and septum formation				This term was made obsolete because it was not defined and the string name implied two separate processes.	GO:0000921|GO:0000917|GO:0000918				True				biological_process											owl:Class	
GO:1900342	biolink:NamedThing	regulation of methane biosynthetic process from dimethyl sulfide	Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.	got7fsn_ti							tt	2012-04-06T02:06:38Z						biological_process											owl:Class	
GO:1904713	biolink:NamedThing	beta-catenin destruction complex binding	Binding to a beta-catenin destruction complex.	got7fsn_ti	APC-Axin-1-beta-catenin complex binding|Axin-APC-beta-catenin-GSK3B complex binding|beta-catenin degradation complex binding|23S APC complex binding|BDC binding						bf	2015-10-05T14:34:14Z						molecular_function											owl:Class	
GO:0060822	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate.	got7fsn_ti	transforming growth factor beta receptor signalling pathway involved in axial mesodermal cell fate specification						dph	2009-08-11T12:55:33Z						biological_process											owl:Class	
GO:2001286	biolink:NamedThing	regulation of caveolin-mediated endocytosis	Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis.	got7fsn_ti	regulation of caveolae-dependent endocytosis|regulation of caveolin-dependent endocytosis|regulation of caveolae-mediated endocytosis						yaf	2011-12-15T04:13:19Z						biological_process											owl:Class	
GO:1901544	biolink:NamedThing	positive regulation of ent-pimara-8(14),15-diene biosynthetic process	Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.	got7fsn_ti	up regulation of ent-pimara-8(14),15-diene biosynthetic process|upregulation of ent-pimara-8(14),15-diene biosynthesis|activation of ent-pimara-8(14),15-diene synthesis|up-regulation of ent-pimara-8(14),15-diene anabolism|upregulation of ent-pimara-8(14),15-diene anabolism|up-regulation of ent-pimara-8(14),15-diene formation|upregulation of ent-pimara-8(14),15-diene biosynthetic process|activation of ent-pimara-8(14),15-diene biosynthesis|up-regulation of ent-pimara-8(14),15-diene biosynthetic process|activation of ent-pimara-8(14),15-diene anabolism|up-regulation of ent-pimara-8(14),15-diene biosynthesis|activation of ent-pimara-8(14),15-diene biosynthetic process|positive regulation of ent-pimara-8(14),15-diene synthesis|activation of ent-pimara-8(14),15-diene formation|upregulation of ent-pimara-8(14),15-diene synthesis|up-regulation of ent-pimara-8(14),15-diene synthesis|positive regulation of ent-pimara-8(14),15-diene formation|up regulation of ent-pimara-8(14),15-diene biosynthesis|upregulation of ent-pimara-8(14),15-diene formation|positive regulation of ent-pimara-8(14),15-diene biosynthesis|up regulation of ent-pimara-8(14),15-diene synthesis|up regulation of ent-pimara-8(14),15-diene anabolism|up regulation of ent-pimara-8(14),15-diene formation|positive regulation of ent-pimara-8(14),15-diene anabolism						di	2012-10-26T11:38:07Z						biological_process											owl:Class	
GO:1990493	biolink:NamedThing	obsolete cyclin H-CDK7 complex	OBSOLETE. A protein complex consisting of cyclin H and cyclin-dependent kinase 7 (CDK7). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	got7fsn_ti	cyclin H-CDK7 complex				This term was made obsolete because it was added in error.		al	2014-09-24T10:08:44Z		True				cellular_component											owl:Class	
GO:0009937	biolink:NamedThing	regulation of gibberellic acid mediated signaling pathway	Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling.	got7fsn_ti	regulation of gibberellic acid mediated signalling													biological_process											owl:Class	
GO:0075337	biolink:NamedThing	obsolete positive regulation of growth or development of symbiont on or near host surface	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	got7fsn_ti	positive regulation of growth or development of symbiont on or near host surface				This term was made obsolete because it contained a conjunction (or).					True				biological_process											owl:Class	
GO:0061454	biolink:NamedThing	release of sequestered calcium ion into cytosol by Golgi	The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.	got7fsn_ti	Golgi calcium ion export						dph	2012-07-27T02:29:43Z						biological_process											owl:Class	
GO:0106058	biolink:NamedThing	positive regulation of calcineurin-mediated signaling	Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling.	got7fsn_ti							hjd	2017-09-18T16:57:06Z						biological_process											owl:Class	
GO:1904534	biolink:NamedThing	negative regulation of telomeric loop disassembly	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly.	got7fsn_ti	inhibition of T loop disassembly|downregulation of T loop disassembly|inhibition of telomeric loop disassembly|down-regulation of telomeric loop disassembly|downregulation of telomeric loop disassembly|down-regulation of T loop disassembly|negative regulation of T loop disassembly|down regulation of T loop disassembly|down regulation of telomeric loop disassembly						nc	2015-07-31T17:15:04Z						biological_process											owl:Class	
GO:0075115	biolink:NamedThing	obsolete modulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the symbiont modulates the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by symbiont of host transmembrane receptor-mediated cAMP signaling				The reason for obsoletion is that there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0016479	biolink:NamedThing	negative regulation of transcription by RNA polymerase I	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.	got7fsn_ti	down regulation of transcription from RNA polymerase I promoter|downregulation of transcription from RNA polymerase I promoter|inhibition of transcription from RNA polymerase I promoter|down-regulation of transcription from RNA polymerase I promoter|negative regulation of transcription from Pol I promoter|negative regulation of transcription from RNA polymerase I promoter													biological_process											owl:Class	
GO:1902082	biolink:NamedThing	positive regulation of calcium ion import into sarcoplasmic reticulum	Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.	got7fsn_ti	upregulation of calcium ion import into sarcoplasmic reticulum|up regulation of calcium ion import into sarcoplasmic reticulum|activation of calcium ion import into sarcoplasmic reticulum|up-regulation of calcium ion import into sarcoplasmic reticulum						rl	2013-04-24T16:08:03Z						biological_process											owl:Class	
GO:0001088	biolink:NamedThing	obsolete transcription factor activity, TFIIE-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	got7fsn_ti	TFIIE-class binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001095	krc	2010-10-28T02:25:22Z		True				molecular_function											owl:Class	
GO:1903674	biolink:NamedThing	regulation of cap-dependent translational initiation	Any process that modulates the frequency, rate or extent of cap-dependent translational initiation.	got7fsn_ti							bf	2014-11-27T19:50:23Z						biological_process											owl:Class	
GO:0060451	biolink:NamedThing	negative regulation of hindgut contraction	Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0005563	biolink:NamedThing	obsolete transfer RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transfer RNA			GO:0030533	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0008462	biolink:NamedThing	obsolete endopeptidase Clp activity	OBSOLETE. Catalysis of the hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are cleaved, for example, succinyl-Leu-Tyr-NHMec which is cleaved at the Tyr-NHMec bond, and Leu-Tyr-Leu-Tyr-Trp which is cleaved at the second Leu-Typ bond (cleavage of the Tyr-Leu and Tyr-Trp bonds also occurs).	got7fsn_ti	ATP-dependent Clp protease|endopeptidase Ti activity|ClpP|caseinolytic protease activity|protease Ti activity|endopeptidase Clp activity|Clp protease			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0019544	biolink:NamedThing	arginine catabolic process to glutamate	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.	got7fsn_ti	arginine degradation to glutamate|arginine breakdown to glutamate											MetaCyc:ARGASEDEG-PWY|MetaCyc:ARG-GLU-PWY		biological_process											owl:Class	
GO:0002665	biolink:NamedThing	negative regulation of T cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction.	got7fsn_ti	down-regulation of T cell tolerance induction|negative regulation of T-cell tolerance induction|down regulation of T cell tolerance induction|negative regulation of T lymphocyte tolerance induction|inhibition of T cell tolerance induction|negative regulation of T-lymphocyte tolerance induction|downregulation of T cell tolerance induction													biological_process											owl:Class	
GO:0019556	biolink:NamedThing	histidine catabolic process to glutamate and formamide	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide.	got7fsn_ti	histidine degradation to glutamate and formamide|histidine breakdown to glutamate and formamide											MetaCyc:HISDEG-PWY		biological_process											owl:Class	
GO:0015010	biolink:NamedThing	tetrahydrocorphin metabolic process	The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.	got7fsn_ti	tetrahydrocorphin metabolism													biological_process											owl:Class	
GO:0035286	biolink:NamedThing	obsolete leg segmentation	OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint.	got7fsn_ti	leg segmentation				This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0035285|GO:0036011				True				biological_process											owl:Class	
GO:1902148	biolink:NamedThing	positive regulation of response to cytokinesis checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling.	got7fsn_ti	upregulation of response to cytokinesis checkpoint signaling|upregulation of response to signal involved in cytokinesis checkpoint|positive regulation of cytokinesis checkpoint effector process|up-regulation of cytokinesis checkpoint effector process|up-regulation of response to signal involved in cytokinesis checkpoint|positive regulation of response to signal involved in cytokinesis checkpoint|up regulation of response to signal involved in cytokinesis checkpoint|up regulation of cytokinesis checkpoint effector process|activation of response to cytokinesis checkpoint signaling|upregulation of cytokinesis checkpoint effector process|activation of response to signal involved in cytokinesis checkpoint|activation of cytokinesis checkpoint effector process|up regulation of response to cytokinesis checkpoint signaling|up-regulation of response to cytokinesis checkpoint signaling						jl	2013-05-21T15:43:58Z			GO:1902150			biological_process											owl:Class	
GO:1902973	biolink:NamedThing	mitotic DNA replication DNA ligation	Any DNA ligation involved in mitotic cell cycle DNA replication.	got7fsn_ti	DNA ligation involved in mitotic cell cycle DNA replication|DNA ligation involved in mitotic DNA replication						jl	2014-05-06T15:20:59Z						biological_process											owl:Class	
GO:0061868	biolink:NamedThing	hepatic stellate cell migration	The orderly movement of a hepatic stellate cell from one site to another.	got7fsn_ti							dph	2017-05-01T13:01:40Z						biological_process											owl:Class	
GO:0062096	biolink:NamedThing	kinetochore disassembly	The disaggregation of a kinetochore into its constituent components.	got7fsn_ti							dph	2018-11-26T16:34:55Z						biological_process											owl:Class	
GO:0099017	biolink:NamedThing	maintenance of protein localization at cell tip	Any process in which localization of a protein is maintained at the cell tip.	got7fsn_ti	maintenance of protein location at cell tip						dos	2016-06-30T15:17:41Z						biological_process											owl:Class	
GO:0032927	biolink:NamedThing	positive regulation of activin receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.	got7fsn_ti	upregulation of activin receptor signaling pathway|positive regulation of activin signaling pathway|positive regulation of activin receptor signalling pathway|up-regulation of activin receptor signaling pathway|up regulation of activin receptor signaling pathway|stimulation of activin receptor signaling pathway|activation of activin receptor signaling pathway|positive regulation of activin signalling pathway													biological_process											owl:Class	
GO:1901103	biolink:NamedThing	gramicidin S biosynthetic process	The chemical reactions and pathways resulting in the formation of gramicidin S.	got7fsn_ti	gramicidin S biosynthesis|gramicidin S synthesis|gramicidin S formation|gramicidin S anabolism						yaf	2012-07-11T02:31:00Z						biological_process											owl:Class	
GO:0043278	biolink:NamedThing	response to morphine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.	got7fsn_ti														biological_process											owl:Class	
GO:1904338	biolink:NamedThing	regulation of dopaminergic neuron differentiation	Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation.	got7fsn_ti							sl	2015-06-11T18:06:19Z						biological_process											owl:Class	
GO:0035561	biolink:NamedThing	regulation of chromatin binding	Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	got7fsn_ti							bf	2010-05-19T10:28:36Z						biological_process											owl:Class	
GO:2000286	biolink:NamedThing	receptor internalization involved in canonical Wnt signaling pathway	A receptor internalization process that contributes to canonical Wnt signaling pathway.	got7fsn_ti	receptor internalization involved in canonical Wnt-activated signaling pathway|receptor internalization involved in Wnt receptor signaling pathway through beta-catenin|receptor internalization involved in frizzled-1 receptor signaling pathway|receptor internalization involved in Wnt receptor signaling pathway via beta-catenin|receptor internalization involved in Wnt receptor signalling pathway through beta-catenin|receptor internalization involved in canonical Wnt receptor signalling pathway|receptor internalization involved in canonical Wnt receptor signaling pathway						mah	2010-12-15T12:25:40Z						biological_process											owl:Class	
GO:2000878	biolink:NamedThing	positive regulation of oligopeptide transport	Any process that activates or increases the frequency, rate or extent of oligopeptide transport.	got7fsn_ti							bf	2011-07-27T01:54:11Z						biological_process											owl:Class	
GO:0002523	biolink:NamedThing	leukocyte migration involved in inflammatory response	The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.	got7fsn_ti	leukocyte migration during inflammatory response|immune cell migration during inflammatory response|leucocyte trafficking during inflammatory response|immune cell trafficking during inflammatory response|leucocyte migration during inflammatory response|leukocyte trafficking during inflammatory response													biological_process											owl:Class	
GO:0070598	biolink:NamedThing	cell wall (1->3)-alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.	got7fsn_ti	cell wall alpha-1,3-glucan synthesis|cell wall alpha-1,3-glucan formation|cell wall alpha-1,3-glucan biosynthetic process|cell wall 1,3-alpha-glucan formation|cell wall 1,3-alpha-glucan biosynthetic process|cell wall alpha-1,3-glucan biosynthesis|cell wall alpha-1,3-glucan anabolism|cell wall 1,3-alpha-glucan synthesis|cell wall 1,3-alpha-glucan anabolism|cell wall 1,3-alpha-glucan biosynthesis						mah	2009-04-28T04:04:59Z						biological_process											owl:Class	
GO:0052491	biolink:NamedThing	obsolete negative regulation by organism of symbiont salicylic acid-mediated defense response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	suppression by organism of symbiont salicylic acid-mediated defense response|negative regulation of symbiont SA-mediated defense response|negative regulation by organism of symbiont salicylic acid-mediated defense response|suppression of symbiont SA mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0071394	biolink:NamedThing	cellular response to testosterone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.	got7fsn_ti							mah	2009-12-11T04:11:29Z						biological_process											owl:Class	
GO:1904972	biolink:NamedThing	negative regulation of viral translation	Any process that stops, prevents or reduces the frequency, rate or extent of viral translation.	got7fsn_ti	down regulation of viral protein formation|down-regulation of viral protein biosynthesis|negative regulation of viral protein formation|down regulation of viral translation|downregulation of viral translation|downregulation of viral protein formation|negative regulation of viral protein synthesis|inhibition of viral protein biosynthetic process|downregulation of viral protein anabolism|down regulation of viral protein anabolism|down-regulation of viral protein formation|negative regulation of viral protein biosynthetic process|inhibition of viral translation|negative regulation of viral protein anabolism|downregulation of viral protein biosynthesis|inhibition of viral protein synthesis|down-regulation of viral protein anabolism|downregulation of viral protein biosynthetic process|down regulation of viral protein synthesis|inhibition of viral protein biosynthesis|down regulation of viral protein biosynthetic process|downregulation of viral protein synthesis|negative regulation of viral protein biosynthesis|inhibition of viral protein formation|down-regulation of viral protein biosynthetic process|inhibition of viral protein anabolism|down-regulation of viral translation|down regulation of viral protein biosynthesis|down-regulation of viral protein synthesis						bhm	2016-02-17T15:53:08Z						biological_process											owl:Class	
GO:1904628	biolink:NamedThing	cellular response to phorbol 13-acetate 12-myristate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.	got7fsn_ti	cellular response to phorbol 12-tetradecanoate 13-acetate|cellular response to response to PMA|cellular response to TPA|cellular response to tetradecanoylphorbol acetate						sl	2015-08-28T13:44:10Z						biological_process											owl:Class	
GO:0036256	biolink:NamedThing	cellular response to methylamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.	got7fsn_ti							bf	2012-06-15T01:08:00Z						biological_process											owl:Class	
GO:0003141	biolink:NamedThing	obsolete transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry	OBSOLETE. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to lateral mesoderm left/right asymmetry determination.	got7fsn_ti	transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signaling pathway involved in lateral mesoderm left/right asymmetry determination|TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry			GO:1900164	This term was made obsolete because it describes involvement of the nodal signaling pathway in lateral mesoderm left/right asymmetry. Nodal proteins are members of the TGF-beta superfamily, but are distinct from TGF-beta proteins themselves. TGF-beta proteins are not currently known to regulate left/right asymmetry in the lateral mesoderm.		tb	2009-09-22T04:03:22Z		True				biological_process											owl:Class	
GO:1900303	biolink:NamedThing	regulation of laminaritriose transport	Any process that modulates the frequency, rate or extent of laminaritriose transport.	got7fsn_ti							tt	2012-04-05T07:57:49Z						biological_process											owl:Class	
GO:1903537	biolink:NamedThing	meiotic cell cycle process involved in oocyte maturation	Any meiotic cell cycle process that is involved in oocyte maturation.	got7fsn_ti	meiosis involved in oocyte maturation						pr	2014-10-09T10:46:14Z						biological_process											owl:Class	
GO:2000726	biolink:NamedThing	negative regulation of cardiac muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.	got7fsn_ti	negative regulation of heart muscle cell differentiation|negative regulation of cardiomyocyte differentiation						vk	2011-06-08T10:51:11Z						biological_process											owl:Class	
GO:0075244	biolink:NamedThing	regulation of oospore formation	Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.	got7fsn_ti														biological_process											owl:Class	
GO:1900057	biolink:NamedThing	positive regulation of leaf senescence	Any process that activates or increases the frequency, rate or extent of leaf senescence.	got7fsn_ti	upregulation of leaf senescence|up-regulation of leaf senescence|activation of leaf senescence|up regulation of leaf senescence						tb	2012-01-24T11:51:36Z						biological_process											owl:Class	
GO:0031392	biolink:NamedThing	regulation of prostaglandin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	got7fsn_ti	regulation of prostaglandin anabolism|regulation of prostaglandin biosynthesis|regulation of prostaglandin formation|regulation of prostaglandin synthesis													biological_process											owl:Class	
GO:0080164	biolink:NamedThing	regulation of nitric oxide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	got7fsn_ti							dhl	2010-09-23T04:02:50Z						biological_process											owl:Class	
GO:0002529	biolink:NamedThing	regulation of plasma kallikrein-kinin cascade	Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade.	got7fsn_ti														biological_process											owl:Class	
GO:0044143	biolink:NamedThing	obsolete positive regulation of development of symbiont on or near host surface	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	got7fsn_ti					The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-06T01:35:48Z		True				biological_process											owl:Class	
GO:1904066	biolink:NamedThing	G protein-coupled receptor signaling pathway involved in dauer larval development	Any G protein-coupled receptor signaling pathway that is involved in dauer larval development.	got7fsn_ti	G-protein coupled receptor protein signaling pathway involved in dauer larval development|G protein coupled receptor protein signalling pathway involved in dauer larval development|G protein coupled receptor protein signaling pathway involved in dauer larval development|G-protein coupled receptor signalling pathway involved in dauer larval development|GPCR signalling pathway involved in dauer larval development|G-protein-coupled receptor protein signalling pathway involved in dauer larval development|G-protein coupled receptor protein signal transduction involved in dauer larval development|GPCR signaling pathway involved in dauer larval development						kmv	2015-03-20T00:51:06Z						biological_process											owl:Class	
GO:0016839	biolink:NamedThing	obsolete other carbon-oxygen lyase activity	OBSOLETE. Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.	got7fsn_ti	other carbon-oxygen lyase activity				This term was made obsolete because it was an unnecessary grouping term.	GO:0016835				True				molecular_function											owl:Class	
GO:0140210	biolink:NamedThing	protein transport along microtubule to kinetochore	Any process in which a protein is transported to the kinetochore along a microtubule.	got7fsn_ti							pg	2018-03-22T07:05:21Z						biological_process											owl:Class	
GO:0052135	biolink:NamedThing	obsolete negative aerotaxis in host	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative aerotaxis within host	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1901185	biolink:NamedThing	negative regulation of ERBB signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway.	got7fsn_ti	negative regulation of EGFR family signaling pathway|down regulation of ErbB signaling|down regulation of ERBB signaling pathway|down-regulation of EGF receptor family signaling pathway|down regulation of EGF receptor family signaling pathway|down-regulation of ERBB signaling pathway|inhibition of ErbB signaling|down regulation of EGFR family signaling pathway|down-regulation of ErbB signaling|negative regulation of EGF receptor family signaling pathway|inhibition of EGF receptor family signaling pathway|negative regulation of ERBB signalling pathway|negative regulation of ErbB signaling|inhibition of ERBB signaling pathway|downregulation of ERBB signaling pathway|downregulation of EGFR family signaling pathway|down regulation of ERBB signalling pathway|downregulation of EGF receptor family signaling pathway|downregulation of ErbB signaling|down-regulation of EGFR family signaling pathway|down-regulation of ERBB signalling pathway|inhibition of EGFR family signaling pathway|downregulation of ERBB signalling pathway|inhibition of ERBB signalling pathway						rl	2012-07-24T07:37:35Z						biological_process											owl:Class	
GO:1904581	biolink:NamedThing	negative regulation of intracellular mRNA localization	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization.	got7fsn_ti	down-regulation of mRNA positioning, intracellular|inhibition of establishment and maintenance of intracellular RNA localization|downregulation of mRNA localization, intracellular|inhibition of mRNA localization, intracellular|down regulation of establishment and maintenance of intracellular RNA localization|negative regulation of intracellular mRNA localisation|down-regulation of mRNA localization, intracellular|negative regulation of mRNA positioning, intracellular|down regulation of intracellular mRNA localisation|down-regulation of intracellular mRNA positioning|downregulation of intracellular mRNA positioning|downregulation of intracellular mRNA localisation|down regulation of mRNA positioning, intracellular|down-regulation of intracellular mRNA localization|negative regulation of establishment and maintenance of intracellular RNA localization|negative regulation of mRNA localization, intracellular|inhibition of intracellular mRNA positioning|negative regulation of intracellular mRNA positioning|inhibition of intracellular mRNA localization|down-regulation of intracellular mRNA localisation|inhibition of intracellular mRNA localisation|down regulation of intracellular mRNA positioning|down regulation of intracellular mRNA localization|downregulation of establishment and maintenance of intracellular RNA localization|downregulation of mRNA positioning, intracellular|inhibition of mRNA positioning, intracellular|down-regulation of establishment and maintenance of intracellular RNA localization|down regulation of mRNA localization, intracellular|downregulation of intracellular mRNA localization						sl	2015-08-19T23:40:32Z						biological_process											owl:Class	
GO:0060178	biolink:NamedThing	regulation of exocyst localization	Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.	got7fsn_ti	regulation of exocyst localisation													biological_process											owl:Class	
GO:1904780	biolink:NamedThing	negative regulation of protein localization to centrosome	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome.	got7fsn_ti	downregulation of protein localization to centrosome|downregulation of protein localisation to centrosome|down-regulation of protein localization to centrosome|negative regulation of protein localisation to centrosome|inhibition of protein localization to centrosome|down regulation of protein localization to centrosome|down regulation of protein localisation to centrosome|down-regulation of protein localisation to centrosome|inhibition of protein localisation to centrosome				An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype).		es	2015-10-30T11:54:47Z						biological_process											owl:Class	
GO:0019313	biolink:NamedThing	allose metabolic process	The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	got7fsn_ti	allose metabolism													biological_process											owl:Class	
GO:0031060	biolink:NamedThing	regulation of histone methylation	Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones.	got7fsn_ti														biological_process											owl:Class	
GO:1901827	biolink:NamedThing	zeaxanthin biosynthetic process	The chemical reactions and pathways resulting in the formation of zeaxanthin.	got7fsn_ti	zeaxanthin anabolism|zeaxanthin biosynthesis|zeaxanthin synthesis|zeaxanthin formation						yaf	2013-01-22T11:37:07Z						biological_process											owl:Class	
GO:1900279	biolink:NamedThing	regulation of CD4-positive, alpha-beta T cell costimulation	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.	got7fsn_ti	regulation of CD4-positive, alpha beta T cell costimulation						rl	2012-04-04T08:56:15Z						biological_process											owl:Class	
GO:0075345	biolink:NamedThing	obsolete modification by symbiont of host protein	OBSOLETE. The covalent alteration by an organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0004235	biolink:NamedThing	obsolete matrilysin activity	OBSOLETE. Catalysis of the cleavage of Ala14-Leu15 and Tyr16-Leu17 in B chain of insulin. No action on collagen types I, II, IV and V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).	got7fsn_ti	putative (or punctuated) metalloproteinase-1 activity|PUMP|matrix metalloproteinase 7 activity|PUMP-1 activity|matrin activity|MMP|PUMP-1 proteinase activity|matrilysin activity|MMP-7|putative metalloproteinase activity|uterine metalloendopeptidase activity|metalloproteinase pump-1|matrix metalloproteinase pump 1|MMP 7			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
PR:000001464	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903238	biolink:NamedThing	positive regulation of leukocyte tethering or rolling	Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling.	got7fsn_ti	up regulation of leukocyte tethering or rolling|activation of leukocyte tethering or rolling|upregulation of leukocyte tethering or rolling|up-regulation of leukocyte tethering or rolling						als	2014-07-31T13:08:01Z						biological_process											owl:Class	
GO:0072577	biolink:NamedThing	endothelial cell apoptotic process	Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.	got7fsn_ti	apoptosis of endothelial cells|programmed cell death, endothelial cells|programmed cell death of endothelial cells by apoptosis|endothelial cell apoptosis|endothelial cell programmed cell death by apoptosis|killing of endothelial cells						mah	2011-02-02T03:56:24Z						biological_process											owl:Class	
GO:0021951	biolink:NamedThing	chemoattraction involved in precerebellar neuron migration	The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration.	got7fsn_ti	positive chemotaxis involved in precerebellar neuron migration													biological_process											owl:Class	
GO:1902670	biolink:NamedThing	carbon dioxide binding	Binding to carbon dioxide.	got7fsn_ti	CO2 binding						bhm	2014-02-04T10:38:41Z						molecular_function											owl:Class	
GO:1902171	biolink:NamedThing	regulation of tocopherol cyclase activity	Any process that modulates the frequency, rate or extent of tocopherol cyclase activity.	got7fsn_ti							tb	2013-05-25T00:41:14Z						biological_process											owl:Class	
GO:1900630	biolink:NamedThing	methanophenazine biosynthetic process	The chemical reactions and pathways resulting in the formation of methanophenazine.	got7fsn_ti	methanophenazine anabolism|methanophenazine synthesis|methanophenazine formation|methanophenazine biosynthesis						tt	2012-05-21T06:12:30Z						biological_process											owl:Class	
GO:0016704	biolink:NamedThing	obsolete oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous	OBSOLETE. A grouping term for oxidoreductases acting on single donors with incorporation of molecular oxygen that cannot be more accurated categorized.	got7fsn_ti	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous				This term was made obsolete because it was an unnecessary grouping term.	GO:0016701				True				molecular_function											owl:Class	
GO:0030209	biolink:NamedThing	dermatan sulfate catabolic process	The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.	got7fsn_ti	chondroitin sulfate B catabolic process|dermatan sulfate catabolism|dermatan sulfate degradation|dermatan sulphate catabolic process|dermatan sulphate catabolism|chondroitin sulfate B catabolism|dermatan sulfate breakdown													biological_process											owl:Class	
GO:1902271	biolink:NamedThing	D3 vitamins binding	Binding to D3 vitamins.	got7fsn_ti							bf	2013-07-01T12:54:37Z						molecular_function											owl:Class	
GO:1904762	biolink:NamedThing	positive regulation of myofibroblast differentiation	Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation.	got7fsn_ti	upregulation of myofibroblast differentiation|activation of myofibroblast cell differentiation|positive regulation of myofibroblast cell differentiation|up-regulation of myofibroblast differentiation|up regulation of myofibroblast differentiation|upregulation of myofibroblast cell differentiation|up regulation of myofibroblast cell differentiation|up-regulation of myofibroblast cell differentiation|activation of myofibroblast differentiation						rph	2015-10-23T12:15:17Z						biological_process											owl:Class	
GO:0032564	biolink:NamedThing	dATP binding	Binding to dATP, deoxyadenosine triphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0019872	biolink:NamedThing	streptomycin biosynthetic process	The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.	got7fsn_ti	streptomycin formation|streptomycin synthesis|streptomycin biosynthesis|streptomycin anabolism													biological_process											owl:Class	
GO:2001012	biolink:NamedThing	mesenchymal cell differentiation involved in renal system development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state.	got7fsn_ti	mesenchymal cell differentiation involved in urinary tract development|mesenchymal cell differentiation involved in urinary system development						yaf	2011-08-09T04:05:14Z						biological_process											owl:Class	
GO:1905069	biolink:NamedThing	allantois development	The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure.	got7fsn_ti	allantoic bud development						cls	2016-03-21T15:18:21Z						biological_process											owl:Class	
GO:0043046	biolink:NamedThing	DNA methylation involved in gamete generation	The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.	got7fsn_ti	de novo DNA methylation													biological_process											owl:Class	
GO:0090187	biolink:NamedThing	positive regulation of pancreatic juice secretion	Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.	got7fsn_ti							tb	2009-12-18T11:03:24Z						biological_process											owl:Class	
GO:1904153	biolink:NamedThing	negative regulation of retrograde protein transport, ER to cytosol	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.	got7fsn_ti	down-regulation of retrograde protein transport, endoplasmic reticulum to cytosol|negative regulation of retrograde protein transport, endoplasmic reticulum to cytosol|downregulation of retrograde protein transport, endoplasmic reticulum to cytosol|inhibition of retrograde protein transport, ER to cytosol|negative regulation of protein dislocation from ER|downregulation of protein dislocation from ER|negative regulation of protein retrotranslocation from ER|inhibition of protein dislocation from ER|down regulation of protein dislocation from ER|inhibition of retrograde protein transport, endoplasmic reticulum to cytosol|down regulation of retrograde protein transport, endoplasmic reticulum to cytosol|downregulation of retrograde protein transport, ER to cytosol|down-regulation of protein dislocation from ER|down regulation of retrograde protein transport, ER to cytosol|down-regulation of retrograde protein transport, ER to cytosol						bf	2015-04-15T09:23:13Z						biological_process											owl:Class	
GO:0070834	biolink:NamedThing	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine	The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.	got7fsn_ti							mah	2009-07-29T03:54:47Z				MetaCyc:PWY4FS-4		biological_process											owl:Class	
GO:0035382	biolink:NamedThing	sterol transmembrane transport	The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti	sterol membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-18T01:24:39Z						biological_process											owl:Class	
GO:0018898	biolink:NamedThing	2,4-dichlorobenzoate metabolic process	The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).	got7fsn_ti	2,4-dichlorobenzoate metabolism											UM-BBD_pathwayID:dcb		biological_process											owl:Class	
GO:0032061	biolink:NamedThing	negative regulation of translation in response to osmotic stress	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti	down regulation of translation in response to osmotic stress|down-regulation of translation in response to osmotic stress|inhibition of translation in response to osmotic stress|downregulation of translation in response to osmotic stress													biological_process											owl:Class	
GO:0033246	biolink:NamedThing	positive regulation of penicillin metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti	positive regulation of penicillin metabolism													biological_process											owl:Class	
GO:0002713	biolink:NamedThing	negative regulation of B cell mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.	got7fsn_ti	negative regulation of B lymphocyte mediated immunity|down regulation of B cell mediated immunity|inhibition of B cell mediated immunity|negative regulation of B-cell mediated immunity|negative regulation of B-lymphocyte mediated immunity|down-regulation of B cell mediated immunity|downregulation of B cell mediated immunity													biological_process											owl:Class	
GO:1901873	biolink:NamedThing	regulation of post-translational protein modification	Any process that modulates the frequency, rate or extent of post-translational protein modification.	got7fsn_ti	regulation of posttranslational modification|regulation of posttranslational amino acid modification|regulation of post-translational modification|regulation of PTM|regulation of post-translational amino acid modification|regulation of posttranslational protein modification						yaf	2013-02-05T10:02:52Z						biological_process											owl:Class	
GO:0032889	biolink:NamedThing	regulation of vacuole fusion, non-autophagic	Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.	got7fsn_ti														biological_process											owl:Class	
GO:0005570	biolink:NamedThing	obsolete small nuclear RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	small nuclear RNA				This term was made obsolete because it represents gene products.	GO:0017069|GO:0000375				True				molecular_function											owl:Class	
GO:0072362	biolink:NamedThing	obsolete regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of glycolysis by negative regulation of transcription from an RNA polymerase II promoter				The reason for obsoletion is that this term represented a GO-CAM model.		mah	2010-11-16T02:59:32Z		True				biological_process											owl:Class	
GO:0070432	biolink:NamedThing	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.	got7fsn_ti	regulation of NOD2 signaling pathway|regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway													biological_process											owl:Class	
GO:1905577	biolink:NamedThing	ganglioside GP1c binding	Binding to ganglioside GP1c.	got7fsn_ti							pga	2016-10-19T11:17:25Z						molecular_function											owl:Class	
GO:1904566	biolink:NamedThing	cellular response to 1-oleoyl-sn-glycerol 3-phosphate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.	got7fsn_ti	cellular response to LPA|cellular response to lysophosphatidic acid|cellular response to oleoyl-L-alpha-lysophosphatidic acid|cellular response to oleoyl lysophosphatidic acid|cellular response to 1-oleoyl lysophosphatidic acid						sl	2015-08-19T15:37:05Z						biological_process											owl:Class	
GO:0019592	biolink:NamedThing	mannitol catabolic process	The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.	got7fsn_ti	mannitol degradation|mannitol breakdown|mannitol catabolism											MetaCyc:MANNIDEG-PWY|MetaCyc:PWY-3861		biological_process											owl:Class	
GO:0019297	biolink:NamedThing	coenzyme B metabolic process	The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.	got7fsn_ti	coenzyme B metabolism													biological_process											owl:Class	
GO:0090048	biolink:NamedThing	obsolete negative regulation of transcription regulator activity	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.	got7fsn_ti	negative regulation of transcription regulator activity				At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term.		tb	2009-08-07T10:25:04Z		True				biological_process											owl:Class	
GO:1904533	biolink:NamedThing	regulation of telomeric loop disassembly	Any process that modulates the frequency, rate or extent of telomeric loop disassembly.	got7fsn_ti	regulation of T loop disassembly						nc	2015-07-31T17:14:58Z						biological_process											owl:Class	
GO:0045650	biolink:NamedThing	negative regulation of macrophage differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.	got7fsn_ti	down-regulation of macrophage differentiation|down regulation of macrophage differentiation|downregulation of macrophage differentiation|inhibition of macrophage differentiation													biological_process											owl:Class	
GO:0006076	biolink:NamedThing	(1->3)-beta-D-glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans.	got7fsn_ti	1,3-beta-D-glucan catabolic process|beta-1,3 glucan degradation|1,3-beta-glucan degradation|1,3-beta-glucan catabolism|1,3-beta-glucan breakdown|beta-1,3 glucan breakdown|beta-1,3 glucan catabolism|beta-1,3 glucan catabolic process													biological_process											owl:Class	
GO:0052124	biolink:NamedThing	obsolete energy taxis within host	OBSOLETE. The directed movement of a motile cell or organism within its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0090425	biolink:NamedThing	acinar cell differentiation	The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.	got7fsn_ti							tb	2012-05-04T09:24:48Z						biological_process											owl:Class	
GO:0023049	biolink:NamedThing	obsolete signal initiation by protein/peptide mediator	OBSOLETE. The process in which a protein/peptide signal causes activation of a receptor.	got7fsn_ti	signal initiation by protein/peptide mediator				This term was made obsolete because the meaning of the term is ambiguous.	GO:0038023|GO:0048018|GO:0007165		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1902013	biolink:NamedThing	poly(glycerol phosphate) teichoic acid metabolic process	The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid.	got7fsn_ti	poly(glycerol phosphate) teichoic acid metabolism						tb	2013-03-22T15:43:45Z						biological_process											owl:Class	
GO:0034263	biolink:NamedThing	positive regulation of autophagy in response to ER overload	The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy.	got7fsn_ti	autophagy in response to ER stress|autophagy in response to endoplasmic reticulum overload													biological_process											owl:Class	
GO:1902501	biolink:NamedThing	lysosomal HOPS complex	Any HOPS complex that is part of a lysosomal membrane.	got7fsn_ti	lysosomal membrane HOPS complex						tb	2013-11-14T00:09:59Z						cellular_component											owl:Class	
GO:0015219	biolink:NamedThing	obsolete protein-DNA complex transmembrane transporter activity	OBSOLETE. Enables the transfer of protein-DNA complexes from one side of a membrane to the other.	got7fsn_ti	DNA-protein complex transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/17005			This term was obsoleted because there is no experimental evidence that this function exists.					True				molecular_function											owl:Class	
GO:0004234	biolink:NamedThing	obsolete macrophage elastase activity	OBSOLETE. Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin.	got7fsn_ti	metalloesterase activity|human macrophage metalloelastase (HME)|macrophage elastase activity|MMP-12|metalloelastase activity|matrix metalloproteinase 12 activity				This term was made obsolete because it represents a gene product.	GO:0004175|GO:0004222				True		EC:3.4.24.65|MetaCyc:3.4.24.65-RXN		molecular_function											owl:Class	
GO:1901569	biolink:NamedThing	fatty acid derivative catabolic process	The chemical reactions and pathways resulting in the breakdown of fatty acid derivative.	got7fsn_ti	fatty acid derivative breakdown|fatty acid derivative degradation|fatty acid derivative catabolism						pr	2012-11-04T17:13:40Z						biological_process											owl:Class	
GO:1990094	biolink:NamedThing	obsolete positive regulation of N-methyl-D-aspartate receptor clustering	OBSOLETE. The positive regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.	got7fsn_ti	positive regulation of N-methyl-D-aspartate receptor clustering|positive regulation of NMDA receptor clustering				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2013-05-06T17:44:00Z		True				biological_process											owl:Class	
CHEBI:35341	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902127	biolink:NamedThing	(-)-lariciresinol metabolic process	The chemical reactions and pathways involving (-)-lariciresinol.	got7fsn_ti	(-)-lariciresinol metabolism						ms	2013-05-21T08:49:33Z						biological_process											owl:Class	
GO:0090342	biolink:NamedThing	regulation of cell aging	Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.	got7fsn_ti							tb	2010-06-02T10:12:37Z						biological_process											owl:Class	
GO:0033531	biolink:NamedThing	stachyose metabolic process	The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	stachyose metabolism													biological_process											owl:Class	
GO:0140209	biolink:NamedThing	zinc ion import into endoplasmic reticulum	The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum.	got7fsn_ti	zinc(2+) import into endoplasmic reticulum|zinc ion import across endoplasmic reticulum|zinc(2+) import across endoplasmic reticulum|zinc ion import into ER				This term covers zinc(2+) import *across* the endoplasmic reticulum membrane through a channel or pore. It does not cover import via vesicle fusion with endoplasmic reticulum membrane, as in this case transport does not involve crossing the membrane.		pg	2018-03-19T10:40:01Z						biological_process											owl:Class	
GO:0060851	biolink:NamedThing	vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment	The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.	got7fsn_ti	vascular endothelial growth factor receptor signalling pathway involved in lymphatic endothelial cell fate commitment						dph	2009-08-12T11:45:19Z						biological_process											owl:Class	
GO:0098850	biolink:NamedThing	extrinsic component of synaptic vesicle membrane	The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0010895	biolink:NamedThing	negative regulation of ergosterol biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.	got7fsn_ti														biological_process											owl:Class	
GO:0009257	biolink:NamedThing	10-formyltetrahydrofolate biosynthetic process	The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.	got7fsn_ti	10-formyl-THF biosynthetic process|10-formyltetrahydrofolate biosynthesis|10-formyl-THF biosynthesis|10-formyltetrahydrofolate anabolism|10-formyltetrahydrofolate formation|10-formyltetrahydrofolate synthesis											MetaCyc:PWY-3841|MetaCyc:1CMET2-PWY		biological_process											owl:Class	
CHEBI:25372	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0106119	biolink:NamedThing	negative regulation of sterol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process.	got7fsn_ti							hjd	2018-04-19T17:44:46Z						biological_process											owl:Class	
GO:1902562	biolink:NamedThing	H4 histone acetyltransferase complex	A protein complex which is capable of H4 histone acetyltransferase activity.	got7fsn_ti	Hpa3 (homo-)dimer|Hpa3 complex				An example of this is Hpa2 in yeast [Q06592] in PMID:23775086 [IDA].		bhm	2013-12-10T14:43:51Z						cellular_component											owl:Class	
GO:0014748	biolink:NamedThing	negative regulation of tonic skeletal muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:1901808	biolink:NamedThing	capsanthin catabolic process	The chemical reactions and pathways resulting in the breakdown of capsanthin.	got7fsn_ti	capsanthin breakdown|capsanthin catabolism|capsanthin degradation						yaf	2013-01-22T10:21:46Z						biological_process											owl:Class	
GO:1905345	biolink:NamedThing	protein localization to cleavage furrow	A process in which a protein is transported to, or maintained in, a location within a cleavage furrow.	got7fsn_ti	protein localisation to cleavage furrow|protein localization in cleavage furrow|protein localisation in cleavage furrow						mah	2016-08-01T13:20:05Z						biological_process											owl:Class	
GO:2000603	biolink:NamedThing	regulation of secondary growth	Any process that modulates the frequency, rate or extent of secondary growth.	got7fsn_ti							tb	2011-04-15T10:30:44Z						biological_process											owl:Class	
GO:0003716	biolink:NamedThing	obsolete RNA polymerase I transcription termination factor activity	OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase I.	got7fsn_ti	Pol I transcription termination factor activity|RNA polymerase I transcription termination factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006363				True				molecular_function											owl:Class	
GO:2000670	biolink:NamedThing	positive regulation of dendritic cell apoptotic process	Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.	got7fsn_ti	positive regulation of dendritic cell apoptosis						pr	2011-05-09T07:34:26Z						biological_process											owl:Class	
GO:0045832	biolink:NamedThing	positive regulation of light-activated channel activity	Any process that activates or increases the frequency, rate or extent of light-activated channel activity.	got7fsn_ti	up regulation of light-activated channel activity|upregulation of light-activated channel activity|activation of light-activated channel activity|stimulation of light-activated channel activity|up-regulation of light-activated channel activity													biological_process											owl:Class	
GO:0006619	biolink:NamedThing	obsolete SRP-independent cotranslational protein-membrane targeting	OBSOLETE. The targeting of proteins to a membrane that occurs during translation and is independent of SRP and signal recognition.	got7fsn_ti	ER translocation|SRP-independent cotranslational protein-membrane targeting|SRP-independent cotranslational membrane targeting				This term was made obsolete because there is no evidence for the existence of this process.					True				biological_process											owl:Class	
GO:1904157	biolink:NamedThing	DN4 thymocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-.	got7fsn_ti							dph	2015-04-15T12:53:07Z						biological_process											owl:Class	
GO:1903755	biolink:NamedThing	positive regulation of SUMO transferase activity	Any process that activates or increases the frequency, rate or extent of SUMO transferase activity.	got7fsn_ti	activation of SUMO transferase activity|up regulation of SMT3 conjugating enzyme|up-regulation of SMT3 conjugating enzyme|activation of SUMO conjugating enzyme activity|upregulation of SMT3 conjugating enzyme|positive regulation of SUMO conjugating enzyme activity|activation of SMT3 conjugating enzyme|upregulation of SUMO conjugating enzyme activity|upregulation of SUMO transferase activity|positive regulation of SMT3 conjugating enzyme|up-regulation of SUMO transferase activity|up regulation of SUMO transferase activity|up-regulation of SUMO conjugating enzyme activity|up regulation of SUMO conjugating enzyme activity						rl	2014-12-18T13:05:59Z						biological_process											owl:Class	
CHEBI:36208	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000183	biolink:NamedThing	negative regulation of progesterone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process.	got7fsn_ti	negative regulation of progesterone formation|negative regulation of progesterone synthesis|negative regulation of progesterone anabolism|negative regulation of progesterone biosynthesis						dph	2010-10-14T07:36:10Z						biological_process											owl:Class	
GO:1900627	biolink:NamedThing	negative regulation of arugosin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process.	got7fsn_ti	negative regulation of arugosin formation|down-regulation of arugosin formation|down-regulation of arugosin anabolism|down regulation of arugosin biosynthesis|negative regulation of arugosin biosynthesis|down regulation of arugosin formation|downregulation of arugosin biosynthetic process|inhibition of arugosin synthesis|negative regulation of arugosin synthesis|inhibition of arugosin formation|inhibition of arugosin biosynthesis|downregulation of arugosin formation|down-regulation of arugosin biosynthetic process|inhibition of arugosin biosynthetic process|down regulation of arugosin synthesis|down regulation of arugosin anabolism|downregulation of arugosin synthesis|negative regulation of arugosin anabolism|down-regulation of arugosin biosynthesis|down-regulation of arugosin synthesis|downregulation of arugosin biosynthesis|inhibition of arugosin anabolism|downregulation of arugosin anabolism|down regulation of arugosin biosynthetic process						di	2012-05-21T05:48:03Z						biological_process											owl:Class	
GO:0046392	biolink:NamedThing	galactarate catabolic process	The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid.	got7fsn_ti	galactarate breakdown|galactarate catabolism|D-galactarate degradation|D-galactarate catabolic process|D-galactarate catabolism|galactarate degradation|D-galactarate breakdown										GO:0019582	MetaCyc:GALACTARDEG-PWY		biological_process											owl:Class	
GO:0033869	biolink:NamedThing	nucleoside bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	nucleoside bisphosphate degradation|nucleoside bisphosphate breakdown|nucleoside bisphosphate catabolism													biological_process											owl:Class	
GO:0019364	biolink:NamedThing	pyridine nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.	got7fsn_ti	pyridine nucleotide catabolism|pyridine nucleotide degradation|pyridine nucleotide breakdown													biological_process											owl:Class	
GO:1902129	biolink:NamedThing	(-)-lariciresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-lariciresinol.	got7fsn_ti	(-)-lariciresinol synthesis|(-)-lariciresinol formation|(-)-lariciresinol biosynthesis|(-)-lariciresinol anabolism						ms	2013-05-21T08:49:44Z						biological_process											owl:Class	
GO:1904871	biolink:NamedThing	positive regulation of protein localization to Cajal body	Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body.	got7fsn_ti	upregulation of protein localisation to Cajal body|up-regulation of protein localization in Cajal body|upregulation of protein localisation in Cajal body|upregulation of protein localization to Cajal body|up-regulation of protein localization to Cajal body|upregulation of protein localization in Cajal body|up-regulation of protein localisation in Cajal body|up regulation of protein localisation in Cajal body|up regulation of protein localization in Cajal body|positive regulation of protein localisation to Cajal body|activation of protein localization in Cajal body|activation of protein localization to Cajal body|activation of protein localisation in Cajal body|up-regulation of protein localisation to Cajal body|activation of protein localisation to Cajal body|positive regulation of protein localization in Cajal body|positive regulation of protein localisation in Cajal body|up regulation of protein localisation to Cajal body|up regulation of protein localization to Cajal body						nc	2015-12-18T11:17:45Z						biological_process											owl:Class	
GO:0032225	biolink:NamedThing	regulation of synaptic transmission, dopaminergic	Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.	got7fsn_ti														biological_process											owl:Class	
GO:0043682	biolink:NamedThing	P-type divalent copper transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out).	got7fsn_ti	copper transmembrane transporter activity, phosphorylative mechanism|Cu2+-exporting ATPase activity|copper-translocating P-type ATPase activity|copper exporting ATPase activity|Cu(2+)-exporting ATPase activity|copper-exporting ATPase activity|copper-transporting ATPase activity										GO:0004008	EC:7.2.2.9|Reactome:R-HSA-6803545|Reactome:R-HSA-936895|RHEA:10376|Reactome:R-HSA-3697838|MetaCyc:3.6.3.4-RXN|Reactome:R-HSA-936802		molecular_function											owl:Class	
GO:0032780	biolink:NamedThing	negative regulation of ATPase activity	Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.	got7fsn_ti	inhibition of ATPase activity|downregulation of ATPase activity|down-regulation of ATPase activity|down regulation of ATPase activity|negative regulation of adenosinetriphosphatase activity													biological_process											owl:Class	
GO:0015805	biolink:NamedThing	S-adenosyl-L-methionine transport	The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	SAM transport|S-adenosylmethionine transport|S-adenosyl methionine transport													biological_process											owl:Class	
GO:1900432	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to heat	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.	got7fsn_ti	downregulation of filamentous growth of a population of unicellular organisms in response to heat|down-regulation of filamentous growth of a population of unicellular organisms in response to heat|inhibition of filamentous growth of a population of unicellular organisms in response to heat|down regulation of filamentous growth of a population of unicellular organisms in response to heat						di	2012-04-25T05:54:15Z						biological_process											owl:Class	
GO:0016969	biolink:NamedThing	obsolete hemerythrin	OBSOLETE. An oxygen carrier found in a few groups of invertebrates, e.g. sipunculid worms, certain molluscs, and crustaceans.	got7fsn_ti	hemerythrin			GO:0005344	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0003306	biolink:NamedThing	Wnt signaling pathway involved in heart development	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.	got7fsn_ti	Wnt receptor signaling pathway involved in heart development|Wnt-activated signaling pathway involved in heart development|Wnt receptor signalling pathway involved in heart development						dph	2009-10-22T12:26:07Z						biological_process											owl:Class	
GO:2000351	biolink:NamedThing	regulation of endothelial cell apoptotic process	Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.	got7fsn_ti	regulation of programmed cell death, endothelial cells|regulation of endothelial cell apoptosis|regulation of endothelial cell programmed cell death by apoptosis|regulation of killing of endothelial cells|regulation of apoptosis of endothelial cells|regulation of programmed cell death of endothelial cells by apoptosis						mah	2011-02-03T10:43:16Z						biological_process											owl:Class	
GO:2000614	biolink:NamedThing	positive regulation of thyroid-stimulating hormone secretion	Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion.	got7fsn_ti	positive regulation of TSH secretion|positive regulation of thyroid stimulating hormone secretion						yaf	2011-04-18T12:56:22Z						biological_process											owl:Class	
GO:0008371	biolink:NamedThing	obsolete biological process	OBSOLETE. These are terms that have been removed from the active process ontology.	got7fsn_ti					This term was made obsolete because it is unnecessary in the OBO flat file format.					True				biological_process											owl:Class	
OBO:OBA_0000121	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904406	biolink:NamedThing	negative regulation of nitric oxide metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process.	got7fsn_ti	inhibition of nitric oxide metabolic process|down-regulation of nitric oxide metabolic process|negative regulation of nitric oxide metabolism|down-regulation of nitric oxide metabolism|down regulation of nitric oxide metabolism|inhibition of nitric oxide metabolism|down regulation of nitric oxide metabolic process|downregulation of nitric oxide metabolic process|downregulation of nitric oxide metabolism						sl	2015-06-24T20:56:41Z						biological_process											owl:Class	
GO:0002878	biolink:NamedThing	negative regulation of acute inflammatory response to non-antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.	got7fsn_ti	down regulation of acute inflammatory response to non-antigenic stimulus|inhibition of acute inflammatory response to non-antigenic stimulus|down-regulation of acute inflammatory response to non-antigenic stimulus|downregulation of acute inflammatory response to non-antigenic stimulus													biological_process											owl:Class	
GO:0005808	biolink:NamedThing	obsolete Golgi-plasma membrane transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Golgi-plasma membrane transport vesicle				This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; a personal communication from John Armstrong indicated that a replacement term was not required, as TGN-Golgi transport is likely to be mediated by tubules rather than vesicles.	GO:0030133				True				cellular_component											owl:Class	
GO:0050516	biolink:NamedThing	obsolete inositol polyphosphate multikinase activity	OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate, and ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.	got7fsn_ti	ArgRIII|IpK2 activity|inositol-polyphosphate multikinase activity|inositol polyphosphate multikinase activity|AtIpk2-beta activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity|IpmK|inositol polyphosphate 6-/3-/5-kinase activity|AtIpk2-alpha activity|AtIpk2beta|AtIpk2alpha|IP3/IP4 dual-specificity 6-/3-kinase activity|IP3/IP4 6-/3-kinase activity				This term was made obsolete because this activity is currently defined as catalyzing two sequential reactions based on a gene product. However, "inositol polyphosphate multikinase activity" in some organisms can catalyze additional reactions. In addition, the reactions listed in the definition can be catalyzed independently by other gene products.					True		EC:2.7.1.151|MetaCyc:2.7.1.151-RXN		molecular_function											owl:Class	
GO:0110145	biolink:NamedThing	magnetosome lumen	The volume enclosed by the membrane of a magnetosome.	got7fsn_ti							kmv	2019-05-30T17:42:14Z						cellular_component											owl:Class	
GO:1900228	biolink:NamedThing	regulation of single-species biofilm formation in or on host organism	Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism.	got7fsn_ti							di	2012-03-23T04:36:54Z						biological_process											owl:Class	
GO:1903702	biolink:NamedThing	esophagus development	The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure.	got7fsn_ti	oesophagus development|esophageal development|gullet development						cls	2014-12-03T14:41:30Z						biological_process											owl:Class	
GO:0030853	biolink:NamedThing	negative regulation of granulocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.	got7fsn_ti	down regulation of granulocyte differentiation|inhibition of granulocyte differentiation|downregulation of granulocyte differentiation|down-regulation of granulocyte differentiation													biological_process											owl:Class	
GO:1903903	biolink:NamedThing	regulation of establishment of T cell polarity	Any process that modulates the frequency, rate or extent of establishment of T cell polarity.	got7fsn_ti	regulation of establishment of T-lymphocyte polarity|regulation of T lymphocyte polarization|regulation of T cell polarization|regulation of establishment of T-cell polarity|regulation of T-cell polarization|regulation of establishment of T lymphocyte polarity						als	2015-02-09T10:50:21Z						biological_process											owl:Class	
GO:1990372	biolink:NamedThing	obsolete process resulting in tolerance to organic acid	OBSOLETE. A response that results in a state of tolerance to organic acid.	got7fsn_ti					This term was obsoleted because it does not represent a clear process.		tt	2014-04-23T22:34:12Z		True				biological_process											owl:Class	
GO:0017081	biolink:NamedThing	chloride channel regulator activity	Binds to and modulates the activity of a chloride channel.	got7fsn_ti												Reactome:R-HSA-383190		molecular_function											owl:Class	
GO:2000698	biolink:NamedThing	positive regulation of epithelial cell differentiation involved in kidney development	Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development.	got7fsn_ti							bf	2011-05-16T04:23:57Z						biological_process											owl:Class	
GO:0032483	biolink:NamedThing	regulation of Rab protein signal transduction	Any process that modulates the frequency, rate or extent of Rab protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:0043150	biolink:NamedThing	DNA synthesis involved in double-strand break repair via homologous recombination	The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.	got7fsn_ti	DNA synthesis during double-strand break repair via homologous recombination													biological_process											owl:Class	
CHEBI:139072	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900536	biolink:NamedThing	obsolete regulation of glucose homeostasis	OBSOLETE. Any process that modulates the frequency, rate or extent of glucose homeostasis.	got7fsn_ti	regulation of glucose homeostasis				This term was obsoleted at the TermGenie Gatekeeper stage.		hjd	2012-05-10T06:52:21Z		True				biological_process											owl:Class	
GO:1990865	biolink:NamedThing	obsolete response to intermittent hypoxia	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an episodic stimulus indicating lowered oxygen tension.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-09-25T15:07:32Z		True				biological_process											owl:Class	
GO:0090338	biolink:NamedThing	positive regulation of formin-nucleated actin cable assembly	Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.	got7fsn_ti							tb	2010-06-01T03:26:31Z						biological_process											owl:Class	
GO:1904727	biolink:NamedThing	negative regulation of replicative senescence	Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence.	got7fsn_ti	downregulation of replicative senescence|down-regulation of replicative senescence|down regulation of replicative senescence|inhibition of replicative senescence						rph	2015-10-14T13:11:31Z						biological_process											owl:Class	
GO:1901305	biolink:NamedThing	negative regulation of spermidine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process.	got7fsn_ti	down-regulation of spermidine anabolism|downregulation of spermidine biosynthetic process|inhibition of spermidine formation|down-regulation of spermidine synthesis|down regulation of spermidine biosynthesis|downregulation of spermidine synthesis|inhibition of spermidine biosynthesis|down-regulation of spermidine biosynthetic process|negative regulation of spermidine synthesis|inhibition of spermidine anabolism|down regulation of spermidine formation|downregulation of spermidine anabolism|down regulation of spermidine biosynthetic process|negative regulation of spermidine biosynthesis|downregulation of spermidine biosynthesis|negative regulation of spermidine anabolism|down regulation of spermidine synthesis|negative regulation of spermidine formation|inhibition of spermidine synthesis|down-regulation of spermidine biosynthesis|downregulation of spermidine formation|inhibition of spermidine biosynthetic process|down regulation of spermidine anabolism|down-regulation of spermidine formation						pm	2012-08-21T13:58:45Z						biological_process											owl:Class	
GO:1904284	biolink:NamedThing	positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.	got7fsn_ti	activation of endogenous peptide antigen processing and presentation via MHC class I|up-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|positive regulation of endogenous peptide antigen processing and presentation via MHC class I|activation of antigen processing and presentation of endogenous peptide antigen via MHC class I|upregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|up-regulation of endogenous peptide antigen processing and presentation via MHC class I|up regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|upregulation of endogenous peptide antigen processing and presentation via MHC class I|up regulation of endogenous peptide antigen processing and presentation via MHC class I						rl	2015-06-04T12:05:49Z						biological_process											owl:Class	
GO:1903911	biolink:NamedThing	positive regulation of receptor clustering	Any process that activates or increases the frequency, rate or extent of receptor clustering.	got7fsn_ti	up regulation of receptor clustering|upregulation of receptor clustering|up-regulation of receptor clustering|activation of receptor clustering						als	2015-02-09T10:56:51Z						biological_process											owl:Class	
GO:0000263	biolink:NamedThing	obsolete heterotrimeric G-protein GTPase, alpha-subunit	OBSOLETE. Subunit of a heterotrimeric G-protein GTPase that contains the guanine nucleotide binding site and possesses GTPase activity.	got7fsn_ti	heterotrimeric G-protein GTPase, alpha-subunit				This term was made obsolete because it does not represent a molecular function.	GO:0005834|GO:0003924				True				molecular_function											owl:Class	
GO:0018943	biolink:NamedThing	organotin metabolic process	The chemical reactions and pathways involving organotin, an organic compound containing a tin atom.	got7fsn_ti	organotin metabolism													biological_process											owl:Class	
GO:1904352	biolink:NamedThing	positive regulation of protein catabolic process in the vacuole	Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.	got7fsn_ti	activation of vacuolar protein catabolic process|up-regulation of vacuolar protein catabolism|positive regulation of vacuolar protein degradation|up-regulation of vacuolar protein breakdown|up-regulation of vacuolar protein catabolic process|positive regulation of vacuolar protein catabolic process|up-regulation of protein catabolic process in the vacuole|activation of protein catabolic process in the vacuole|up regulation of vacuolar protein degradation|up regulation of vacuolar protein catabolism|upregulation of vacuolar protein catabolic process|up regulation of vacuolar protein catabolic process|upregulation of vacuolar protein degradation|activation of vacuolar protein breakdown|activation of vacuolar protein degradation|upregulation of vacuolar protein breakdown|positive regulation of vacuolar protein breakdown|upregulation of vacuolar protein catabolism|up-regulation of vacuolar protein degradation|up regulation of vacuolar protein breakdown|up regulation of protein catabolic process in the vacuole|upregulation of protein catabolic process in the vacuole|activation of vacuolar protein catabolism|positive regulation of vacuolar protein catabolism						rl	2015-06-12T09:10:49Z						biological_process											owl:Class	
GO:1904069	biolink:NamedThing	ascaroside metabolic process	The chemical reactions and pathways involving ascaroside.	got7fsn_ti	ascaroside metabolism						kmv	2015-03-20T02:40:14Z						biological_process											owl:Class	
GO:0100031	biolink:NamedThing	obsolete regulation of histone methylation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone methylation.	got7fsn_ti					This term was obsoleted because it describes a process that does not exist.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0061884	biolink:NamedThing	regulation of mini excitatory postsynaptic potential	Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.	got7fsn_ti							dph	2017-05-30T15:35:46Z						biological_process											owl:Class	
GO:0046900	biolink:NamedThing	tetrahydrofolylpolyglutamate metabolic process	The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.	got7fsn_ti	tetrahydrofolyl-[Glu](n) metabolic process|tetrahydrofolyl-[Glu](n) metabolism|tetrahydrofolylpolyglutamate metabolism													biological_process											owl:Class	
GO:1904487	biolink:NamedThing	cellular response to 17alpha-ethynylestradiol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus.	got7fsn_ti							mr	2015-07-15T22:31:42Z						biological_process											owl:Class	
GO:0030577	biolink:NamedThing	Lands organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies.	got7fsn_ti	Lands organization and biogenesis|LYSP100-associated nuclear domain organization|Lands organisation				See also the cellular component term 'Lands ; GO:0016606'.									biological_process											owl:Class	
GO:0010766	biolink:NamedThing	negative regulation of sodium ion transport	Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0008573	biolink:NamedThing	obsolete peroxisome-assembly ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. ATP hydrolysis to import and assemble peroxisome components into the organelle.	got7fsn_ti	peroxisome-assembly ATPase activity			GO:0016887	This term was made obsolete because it incorporates process information.	GO:0007031				True				molecular_function											owl:Class	
GO:1904314	biolink:NamedThing	cellular response to methamphetamine hydrochloride	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.	got7fsn_ti	cellular response to methamphetamine HCL						sl	2015-06-10T17:47:15Z						biological_process											owl:Class	
GO:0120214	biolink:NamedThing	negative regulation of histidine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process.	got7fsn_ti	down regulation of histidine anabolism|down regulation of histidine biosynthesis|negative regulation of histidine synthesis|downregulation of histidine anabolism|downregulation of histidine formation|down regulation of histidine synthesis|down-regulation of histidine biosynthesis|downregulation of histidine synthesis|down-regulation of histidine anabolism|inhibition of histidine formation|down-regulation of histidine synthesis|negative regulation of histidine formation|down regulation of histidine formation|inhibition of histidine synthesis|negative regulation of histidine anabolism|down-regulation of histidine biosynthetic process|inhibition of histidine anabolism|negative regulation of histidine biosynthesis|downregulation of histidine biosynthesis|downregulation of histidine biosynthetic process|inhibition of histidine biosynthetic process|down-regulation of histidine formation|inhibition of histidine biosynthesis|down regulation of histidine biosynthetic process						krc	2019-06-27T20:56:35Z						biological_process											owl:Class	
GO:0031660	biolink:NamedThing	obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle	OBSOLETE. Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.	got7fsn_ti	regulation of cyclin-dependent protein kinase activity involved in G2/M|G2/M-specific regulation of cyclin-dependent protein kinase activity|regulation of cyclin-dependent protein kinase activity during G2/M				This term was obsoleted because it is a MF represented as a BP.	GO:0010389				True				biological_process											owl:Class	
GO:0043922	biolink:NamedThing	negative regulation by host of viral transcription	Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription.	got7fsn_ti	negative regulation of viral transcription by host													biological_process											owl:Class	
GO:0005311	biolink:NamedThing	obsolete sodium:dicarboxylate/tricarboxylate symporter activity	OBSOLETE. Catalysis of the reaction: (dicarboxylate or tricarboxylate)(out) + Na+(out) = (dicarboxylate or tricarboxylate)(in) + Na+(in).	got7fsn_ti	sodium:dicarboxylate/tricarboxylate cotransporter activity|sodium:dicarboxylate/tricarboxylate symporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0005310|GO:0005343|GO:0015142				True				molecular_function											owl:Class	
GO:0032716	biolink:NamedThing	negative regulation of interleukin-7 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production.	got7fsn_ti	negative regulation of interleukin-7 biosynthetic process|down regulation of interleukin-7 production|negative regulation of IL-7 production|inhibition of interleukin-7 production|negative regulation of interleukin-7 secretion|downregulation of interleukin-7 production|down-regulation of interleukin-7 production										GO:0045412|GO:0150113			biological_process											owl:Class	
GO:0120011	biolink:NamedThing	intermembrane sterol transfer	The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-16T22:15:40Z						biological_process											owl:Class	
GO:0044867	biolink:NamedThing	modulation by host of viral catalytic activity	The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected.	got7fsn_ti							jl	2014-09-18T11:29:25Z						biological_process											owl:Class	
GO:0031136	biolink:NamedThing	positive regulation of conjugation	Any process that increases the rate or frequency of conjugation.	got7fsn_ti	up regulation of conjugation|activation of conjugation|up-regulation of conjugation|stimulation of conjugation|upregulation of conjugation													biological_process											owl:Class	
PR:000001392	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904323	biolink:NamedThing	regulation of inhibitory G protein-coupled receptor phosphorylation	Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.	got7fsn_ti	regulation of inhibitory G-protein coupled receptor phosphorylation						sl	2015-06-10T19:46:37Z						biological_process											owl:Class	
GO:1901711	biolink:NamedThing	negative regulation of homoserine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process.	got7fsn_ti	down regulation of homoserine biosynthesis|down regulation of homoserine formation|downregulation of homoserine biosynthetic process|downregulation of homoserine biosynthesis|downregulation of homoserine synthesis|down-regulation of homoserine anabolism|down regulation of homoserine synthesis|inhibition of homoserine synthesis|down regulation of homoserine biosynthetic process|inhibition of homoserine formation|downregulation of homoserine formation|down regulation of homoserine anabolism|down-regulation of homoserine formation|inhibition of homoserine biosynthesis|down-regulation of homoserine synthesis|down-regulation of homoserine biosynthesis|downregulation of homoserine anabolism|down-regulation of homoserine biosynthetic process|negative regulation of homoserine synthesis|inhibition of homoserine biosynthetic process|inhibition of homoserine anabolism|negative regulation of homoserine biosynthesis|negative regulation of homoserine formation|negative regulation of homoserine anabolism						mcc	2012-12-19T16:02:00Z						biological_process											owl:Class	
GO:0009809	biolink:NamedThing	lignin biosynthetic process	The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.	got7fsn_ti	lignin anabolism|lignin synthesis|lignin formation|lignin biosynthesis											MetaCyc:PWY-361		biological_process											owl:Class	
GO:0042417	biolink:NamedThing	dopamine metabolic process	The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	got7fsn_ti	dopamine metabolism													biological_process											owl:Class	
GO:0008161	biolink:NamedThing	obsolete carbamate resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	carbamate resistance			GO:0046681	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0015025	biolink:NamedThing	obsolete GPI-anchored membrane-bound receptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	GPI-anchored membrane-bound receptor			GO:0031225	This term was made obsolete because it contains both component and function information.					True				molecular_function											owl:Class	
GO:1903132	biolink:NamedThing	regulation of tube lumen cavitation	Any process that modulates the frequency, rate or extent of tube lumen cavitation.	got7fsn_ti							dph	2014-06-25T20:18:58Z						biological_process											owl:Class	
GO:0009159	biolink:NamedThing	deoxyribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	deoxyribonucleoside monophosphate degradation|deoxyribonucleoside monophosphate breakdown|deoxyribonucleoside monophosphate catabolism													biological_process											owl:Class	
GO:0061335	biolink:NamedThing	cell growth involved in Malpighian tubule morphogenesis	The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.	got7fsn_ti							dph	2010-09-28T02:08:25Z						biological_process											owl:Class	
GO:0120264	biolink:NamedThing	regulation of chromosome attachment to the nuclear envelope	Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20020					krc	2020-09-29T20:26:49Z						biological_process											owl:Class	
GO:1905939	biolink:NamedThing	regulation of gonad development	Any process that modulates the frequency, rate or extent of gonad development.	got7fsn_ti	regulation of gonadogenesis						hbye	2017-02-09T17:01:50Z						biological_process											owl:Class	
GO:0071026	biolink:NamedThing	cytoplasmic RNA surveillance	The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.	got7fsn_ti	cytoplasmic aberrant RNA catabolic process|cytoplasmic RNA quality control						krc	2009-07-28T03:14:03Z						biological_process											owl:Class	
PR:000007495	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048374	biolink:NamedThing	regulation of lateral mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination.	got7fsn_ti	regulation of lateral plate mesodermal cell fate determination|regulation of lateral plate mesoderm cell fate determination|regulation of lateral mesoderm cell fate determination													biological_process											owl:Class	
PO:0025025	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002583	biolink:NamedThing	regulation of antigen processing and presentation of peptide antigen	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.	got7fsn_ti	regulation of peptide antigen processing and presentation													biological_process											owl:Class	
GO:1901628	biolink:NamedThing	positive regulation of postsynaptic membrane organization	Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization.	got7fsn_ti	activation of postsynaptic membrane organisation|activation of postsynaptic membrane organization|upregulation of postsynaptic membrane organisation|positive regulation of post-synaptic membrane organization|up regulation of postsynaptic membrane organization|positive regulation of postsynaptic membrane organisation|upregulation of postsynaptic membrane organization|up-regulation of postsynaptic membrane organisation|up-regulation of postsynaptic membrane organization|up regulation of postsynaptic membrane organisation						ans	2012-11-15T11:40:24Z						biological_process											owl:Class	
GO:1905383	biolink:NamedThing	protein localization to presynapse	A process in which a protein is transported to, or maintained in, a location within a presynapse.	got7fsn_ti	recruitment of presynaptic proteins|protein localization in presynapse|protein localisation to presynapse|protein localisation in presynapse						dos	2016-08-18T14:42:59Z						biological_process											owl:Class	
PR:000007563	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904370	biolink:NamedThing	regulation of protein localization to actin cortical patch	Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch.	got7fsn_ti	regulation of protein localisation to actin cortical patch						sl	2015-06-18T22:23:31Z						biological_process											owl:Class	
GO:1900143	biolink:NamedThing	positive regulation of oligodendrocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process.	got7fsn_ti	upregulation of oligodendrocyte apoptosis|up-regulation of oligodendrocyte apoptotic process|up-regulation of oligodendrocyte apoptosis|positive regulation of oligodendrocyte apoptosis|upregulation of oligodendrocyte apoptotic process|activation of oligodendrocyte apoptotic process|up regulation of oligodendrocyte apoptotic process|activation of oligodendrocyte apoptosis|up regulation of oligodendrocyte apoptosis						yaf	2012-03-06T10:22:54Z						biological_process											owl:Class	
GO:0002061	biolink:NamedThing	pyrimidine nucleobase binding	Binding to a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton.	got7fsn_ti	1,3-diazine binding|pyrimidine base binding|pyrimidine binding													molecular_function											owl:Class	
GO:0070959	biolink:NamedThing	negative regulation of neutrophil mediated killing of fungus	Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.	got7fsn_ti	down-regulation of neutrophil mediated killing of fungus|down regulation of neutrophil mediated killing of fungus|inhibition of neutrophil mediated killing of fungus|downregulation of neutrophil mediated killing of fungus						mah	2009-10-01T02:20:17Z						biological_process											owl:Class	
GO:1902073	biolink:NamedThing	positive regulation of hypoxia-inducible factor-1alpha signaling pathway	Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.	got7fsn_ti	upregulation of HIF1alpha pathway|activation of hypoxia-inducible factor-1alpha signaling pathway|positive regulation of HIF1alpha pathway|up regulation of HIF1alpha pathway|upregulation of hypoxia-inducible factor-1alpha signaling pathway|up-regulation of HIF1alpha pathway|positive regulation of hypoxia-inducible factor-1alpha signalling pathway|upregulation of hypoxia-inducible factor-1alpha signalling pathway|up regulation of hypoxia-inducible factor-1alpha signaling pathway|activation of HIF1alpha pathway|up-regulation of hypoxia-inducible factor-1alpha signalling pathway|activation of hypoxia-inducible factor-1alpha signalling pathway|hypoxic stabilization of HIF1A|up regulation of hypoxia-inducible factor-1alpha signalling pathway|up-regulation of hypoxia-inducible factor-1alpha signaling pathway						bf	2013-04-18T13:28:30Z						biological_process											owl:Class	
UBERON:0001648	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042690	biolink:NamedThing	negative regulation of crystal cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation.	got7fsn_ti	down regulation of crystal cell differentiation|inhibition of crystal cell differentiation|downregulation of crystal cell differentiation|down-regulation of crystal cell differentiation													biological_process											owl:Class	
GO:1901198	biolink:NamedThing	positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion	Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion.	got7fsn_ti	positive regulation of calcium ion transport into cytosol involved in cellular response to Ca2+ ion						al	2012-07-27T11:07:43Z						biological_process											owl:Class	
GO:0046381	biolink:NamedThing	CMP-N-acetylneuraminate metabolic process	The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.	got7fsn_ti	CMP-N-acetylneuraminate metabolism													biological_process											owl:Class	
GO:0002621	biolink:NamedThing	positive regulation of non-professional antigen presenting cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.	got7fsn_ti	up-regulation of non-professional antigen presenting cell antigen processing and presentation|activation of non-professional antigen presenting cell antigen processing and presentation|stimulation of non-professional antigen presenting cell antigen processing and presentation|upregulation of non-professional antigen presenting cell antigen processing and presentation|up regulation of non-professional antigen presenting cell antigen processing and presentation													biological_process											owl:Class	
GO:0018869	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031263	biolink:NamedThing	obsolete ATPase-coupled amine transporter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in).	got7fsn_ti	amine ABC transporter|amine-transporting ATPase activity|ATP-dependent amine transporter activity	https://github.com/geneontology/go-ontology/issues/17164			This term was obsoleted because it corresponds to a wide range of substrates not necessarily transported by the same transporter. See https://en.wikipedia.org/wiki/Amine.					True				molecular_function											owl:Class	
GO:0000181	biolink:NamedThing	obsolete cytosolic small ribosomal subunit	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytosolic small ribosomal subunit				This term was made obsolete because more specific children exist.	GO:0022627				True				cellular_component											owl:Class	
GO:0006684	biolink:NamedThing	sphingomyelin metabolic process	The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.	got7fsn_ti	sphingomyelin metabolism													biological_process											owl:Class	
GO:2000008	biolink:NamedThing	regulation of protein localization to cell surface	Any process that modulates the frequency, rate or extent of protein localization to the cell surface.	got7fsn_ti	regulation of protein localisation at cell surface|regulation of protein localization at cell surface						jl	2010-08-04T01:43:48Z						biological_process											owl:Class	
GO:0039555	biolink:NamedThing	obsolete suppression by virus of host MDA-5 activity via MDA-5 binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by binding to MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector.	got7fsn_ti	suppression by virus of host MDA5 activity by MDA-5 binding				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-09T04:06:46Z		True				biological_process											owl:Class	
GO:0031602	biolink:NamedThing	obsolete ER proteasome core complex	OBSOLETE. The core complex of a proteasome located in the endoplasmic reticulum of a cell.	got7fsn_ti					This term was made obsolete because there is no evidence in the literature of its existence.					True				cellular_component											owl:Class	
GO:0050676	biolink:NamedThing	negative regulation of urothelial cell proliferation	Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.	got7fsn_ti	downregulation of urothelial cell proliferation|inhibition of urothelial cell proliferation|down-regulation of urothelial cell proliferation|down regulation of urothelial cell proliferation													biological_process											owl:Class	
GO:0099069	biolink:NamedThing	synaptic vesicle tethering involved in synaptic vesicle exocytosis	The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0090337	biolink:NamedThing	regulation of formin-nucleated actin cable assembly	Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.	got7fsn_ti							tb	2010-06-01T03:26:31Z						biological_process											owl:Class	
GO:2000094	biolink:NamedThing	negative regulation of mesonephric nephron tubule epithelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.	got7fsn_ti							dph	2010-09-03T06:12:28Z						biological_process											owl:Class	
GO:0010372	biolink:NamedThing	positive regulation of gibberellin biosynthetic process	Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.	got7fsn_ti	positive regulation of gibberellic acid biosynthetic process													biological_process											owl:Class	
GO:0032464	biolink:NamedThing	positive regulation of protein homooligomerization	Any process that activates or increases the frequency, rate or extent of protein homooligomerization.	got7fsn_ti	activation of protein homooligomerization|stimulation of protein homooligomerization|up-regulation of protein homooligomerization|induction of protein homooligomerization|upregulation of protein homooligomerization|up regulation of protein homooligomerization													biological_process											owl:Class	
GO:1903245	biolink:NamedThing	obsolete regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	OBSOLETE. Any process that modulates the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.	got7fsn_ti	regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|regulation of If activation by beta-adrenergic receptor signaling pathway|regulation of activation of funny current by beta-adrenergic receptor signaling pathway|regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/14733			This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		rl	2014-08-04T11:53:54Z		True				biological_process											owl:Class	
GO:0101028	biolink:NamedThing	positive regulation of liquid surface tension	Any process that activates or increases the surface tension of a liquid.	got7fsn_ti	positive regulation of surface tension of a liquid													biological_process											owl:Class	
GO:0048715	biolink:NamedThing	negative regulation of oligodendrocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.	got7fsn_ti	downregulation of oligodendrocyte differentiation|inhibition of oligodendrocyte differentiation|down regulation of oligodendrocyte differentiation|down-regulation of oligodendrocyte differentiation													biological_process											owl:Class	
GO:1900097	biolink:NamedThing	positive regulation of dosage compensation by inactivation of X chromosome	Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.	got7fsn_ti	activation of chromosome inactivation|up-regulation of X chromosome inactivation|activation of dosage compensation, by inactivation of X chromosome|upregulation of chromosome inactivation|up-regulation of dosage compensation, by inactivation of X chromosome|up regulation of Barr body formation|positive regulation of X chromosome inactivation|up regulation of X chromosome inactivation|up-regulation of chromosome inactivation|positive regulation of chromosome inactivation|upregulation of Barr body formation|upregulation of dosage compensation, by inactivation of X chromosome|activation of X chromosome inactivation|up-regulation of Barr body formation|up regulation of dosage compensation, by inactivation of X chromosome|upregulation of X chromosome inactivation|activation of Barr body formation|up regulation of chromosome inactivation|positive regulation of Barr body formation						hjd	2012-02-14T07:29:52Z						biological_process											owl:Class	
GO:1901508	biolink:NamedThing	positive regulation of acylglycerol transport	Any process that activates or increases the frequency, rate or extent of acylglycerol transport.	got7fsn_ti	activation of acylglycerol transport|positive regulation of glyceride transport|up-regulation of glyceride transport|up regulation of acylglycerol transport|upregulation of acylglycerol transport|upregulation of glyceride transport|up regulation of glyceride transport|activation of glyceride transport|up-regulation of acylglycerol transport						sart	2012-10-17T11:06:23Z						biological_process											owl:Class	
GO:1904812	biolink:NamedThing	rRNA acetylation involved in maturation of SSU-rRNA	Any rRNA acetylation that is involved in maturation of SSU-rRNA.	got7fsn_ti	rRNA acetylation involved in processing of 20S pre-rRNA|rRNA acetylation involved in SSU-rRNA maturation						al	2015-11-11T15:38:41Z						biological_process											owl:Class	
GO:0099545	biolink:NamedThing	trans-synaptic signaling by trans-synaptic complex	Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.	got7fsn_ti														biological_process											owl:Class	
GO:0010345	biolink:NamedThing	suberin biosynthetic process	The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols.	got7fsn_ti												MetaCyc:PWY-1121		biological_process											owl:Class	
GO:0018929	biolink:NamedThing	methyl fluoride metabolic process	The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils.	got7fsn_ti	methyl fluoride metabolism											UM-BBD_pathwayID:mf		biological_process											owl:Class	
GO:0071641	biolink:NamedThing	negative regulation of macrophage inflammatory protein 1 alpha production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.	got7fsn_ti	negative regulation of CCL3 production|negative regulation of macrophage inflammatory protein production|negative regulation of chemokine (C-C motif) ligand 3 production|negative regulation of MIP-1a production						mah	2010-02-12T10:39:51Z						biological_process											owl:Class	
GO:0034167	biolink:NamedThing	regulation of toll-like receptor 10 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 10 signalling pathway|regulation of TLR10 signaling pathway													biological_process											owl:Class	
GO:0009473	biolink:NamedThing	obsolete cytochrome c7 (triheme)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytochrome c7 (triheme)				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:2000689	biolink:NamedThing	actomyosin contractile ring assembly actin filament organization	An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis.	got7fsn_ti	regulation of actin filament localization of cytokinesis, contractile ring assembly|regulation of actin filament localization of cytokinesis, actomyosin ring formation|actin filament organization of constriction ring assembly|regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation|actin filament organization involved in cytokinetic actomyosin contractile ring assembly|actin filament organisation of cytokinesis, actomyosin ring biosynthesis|actin filament organization of cytokinesis, actomyosin ring formation|regulation of actin filament localization of contractile ring assembly|regulation of actin filament localization of constriction ring assembly|actin filament organization of cytokinesis, contractile ring assembly|actin filament organization of cytokinesis, actomyosin ring biosynthesis|actin filament organisation of cytokinesis, actomyosin contractile ring formation|actin filament organisation of cytokinesis, actomyosin ring formation|regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis|actin filament organization of contractile ring assembly|actin filament organisation of cytokinesis, actomyosin contractile ring assembly|actin filament organisation of constriction ring assembly|actin filament organisation of contractile ring assembly|actin filament organisation of cytokinesis, contractile ring assembly|regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly|actin filament organization of cytokinesis, actomyosin contractile ring assembly|actin filament organization of cytokinesis, actomyosin contractile ring formation						mah	2011-05-17T11:48:12Z						biological_process											owl:Class	
GO:1905378	biolink:NamedThing	cellular response to D-galactose	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.	got7fsn_ti	cellular response to D-galacto-hexose|cellular response to D-Gal						sl	2016-08-17T22:17:32Z						biological_process											owl:Class	
GO:0046317	biolink:NamedThing	regulation of glucosylceramide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.	got7fsn_ti	regulation of glucosylceramide formation|regulation of glucosylceramide synthesis|regulation of glucosylceramide anabolism|regulation of glucosylceramide biosynthesis													biological_process											owl:Class	
GO:1905448	biolink:NamedThing	positive regulation of mitochondrial ATP synthesis coupled electron transport	Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.	got7fsn_ti	up regulation of mitochondrial ATP synthesis coupled electron transport|up-regulation of mitochondrial ATP synthesis coupled electron transport|activation of mitochondrial ATP synthesis coupled electron transport|upregulation of mitochondrial ATP synthesis coupled electron transport						dph	2016-09-15T18:58:14Z						biological_process											owl:Class	
GO:2001101	biolink:NamedThing	maltopentaose transport	The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:18:36Z						biological_process											owl:Class	
GO:1901795	biolink:NamedThing	3-(3-hydroxyphenyl)propanoate biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate.	got7fsn_ti	3-(3-hydroxyphenyl)propanoate synthesis|3-(3-hydroxyphenyl)propanoate biosynthesis|3-(3-hydroxyphenyl)propanoate anabolism|3-(3-hydroxyphenyl)propanoate formation						yaf	2013-01-16T11:47:21Z						biological_process											owl:Class	
GO:1900488	biolink:NamedThing	negative regulation of [2Fe-2S] cluster assembly	Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly.	got7fsn_ti	inhibition of [2Fe-2S] cluster biosynthetic process|inhibition of 2Fe-2S cluster assembly|down regulation of [2Fe-2S] cluster biosynthetic process|down-regulation of [2Fe-2S] cluster biosynthetic process|downregulation of 2Fe-2S cluster assembly|downregulation of [2Fe-2S] cluster biosynthetic process|down-regulation of [2Fe-2S] cluster assembly|downregulation of [2Fe-2S] cluster assembly|down regulation of 2Fe-2S cluster assembly|inhibition of [2Fe-2S] cluster assembly|negative regulation of [2Fe-2S] cluster biosynthetic process|negative regulation of 2Fe-2S cluster assembly|down regulation of [2Fe-2S] cluster assembly|down-regulation of 2Fe-2S cluster assembly						tt	2012-05-02T01:22:32Z						biological_process											owl:Class	
GO:0048712	biolink:NamedThing	negative regulation of astrocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.	got7fsn_ti	down regulation of astrocyte differentiation|down-regulation of astrocyte differentiation|inhibition of astrocyte differentiation|downregulation of astrocyte differentiation													biological_process											owl:Class	
GO:0098936	biolink:NamedThing	intrinsic component of postsynaptic membrane	The component of the postsynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to postsynaptic membrane													cellular_component											owl:Class	
GO:0015505	biolink:NamedThing	uracil:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).	got7fsn_ti	uracil permease activity													molecular_function											owl:Class	
GO:0000742	biolink:NamedThing	karyogamy involved in conjugation with cellular fusion	During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy.	got7fsn_ti	karyogamy during conjugation with cellular fusion													biological_process											owl:Class	
GO:1901542	biolink:NamedThing	regulation of ent-pimara-8(14),15-diene biosynthetic process	Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.	got7fsn_ti	regulation of ent-pimara-8(14),15-diene synthesis|regulation of ent-pimara-8(14),15-diene formation|regulation of ent-pimara-8(14),15-diene biosynthesis|regulation of ent-pimara-8(14),15-diene anabolism						di	2012-10-26T11:37:54Z						biological_process											owl:Class	
GO:0019434	biolink:NamedThing	sophorosyloxydocosanoate metabolic process	The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon.	got7fsn_ti	sophorosyloxydocosanoate metabolism													biological_process											owl:Class	
GO:2000116	biolink:NamedThing	regulation of cysteine-type endopeptidase activity	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity.	got7fsn_ti	regulation of lysosomal cysteine-type endopeptidase|regulation of thiol endopeptidase activity						jl	2010-09-23T10:24:33Z						biological_process											owl:Class	
GO:0032114	biolink:NamedThing	regulation of glucose-6-phosphatase activity	Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0004258	biolink:NamedThing	obsolete vacuolar carboxypeptidase Y	OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity.	got7fsn_ti	vacuolar carboxypeptidase Y				This term was made obsolete because it contains both component and function information.	GO:0004185|GO:0005773				True				molecular_function											owl:Class	
GO:0071681	biolink:NamedThing	cellular response to indole-3-methanol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.	got7fsn_ti	cellular response to indole-3-carbinol						mah	2010-02-18T04:05:29Z						biological_process											owl:Class	
GO:0052319	biolink:NamedThing	regulation of phytoalexin biosynthetic process	Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.	got7fsn_ti	regulation of phytoalexin biosynthesis													biological_process											owl:Class	
GO:1902918	biolink:NamedThing	poly(5-hydroxyvalerate) metabolic process	The chemical reactions and pathways involving poly(5-hydroxyvalerate).	got7fsn_ti	poly(5-hydroxyvalerate) metabolism						tt	2014-04-21T18:47:06Z						biological_process											owl:Class	
GO:1903508	biolink:NamedThing	positive regulation of nucleic acid-templated transcription	Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription.	got7fsn_ti	activation of nucleic acid-templated transcription|up-regulation of nucleic acid-templated transcription|upregulation of nucleic acid-templated transcription|up regulation of nucleic acid-templated transcription						pr	2014-10-01T14:45:04Z						biological_process											owl:Class	
GO:0070638	biolink:NamedThing	pyridine nucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.	got7fsn_ti	pyridine nucleoside catabolism|pyridine nucleoside degradation|pyridine nucleoside breakdown						mah	2009-05-07T02:27:14Z						biological_process											owl:Class	
GO:1903612	biolink:NamedThing	positive regulation of calcium-dependent ATPase activity	Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity.	got7fsn_ti	up regulation of calcium-dependent ATPase activity|up-regulation of calcium-dependent ATPase activity|activation of calcium-dependent ATPase activity|upregulation of calcium-dependent ATPase activity						sl	2014-11-18T00:43:06Z						biological_process											owl:Class	
GO:1903714	biolink:NamedThing	isoleucine transmembrane transport	The directed movement of isoleucine across a membrane.	got7fsn_ti							vw	2014-12-06T08:19:05Z						biological_process											owl:Class	
GO:0004898	biolink:NamedThing	obsolete gp130	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	gp130				This term was made obsolete because it represents a gene product.	GO:0004897|GO:0004915|GO:0004921				True				molecular_function											owl:Class	
GO:0071232	biolink:NamedThing	cellular response to histidine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.	got7fsn_ti							mah	2009-12-03T02:09:15Z						biological_process											owl:Class	
GO:0006131	biolink:NamedThing	obsolete dihydrolipoamide reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dihydrolipoamide reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051068|GO:0022900|GO:0004148				True				biological_process											owl:Class	
GO:1900274	biolink:NamedThing	regulation of phospholipase C activity	Any process that modulates the frequency, rate or extent of phospholipase C activity.	got7fsn_ti	regulation of phosphatidase C|regulation of lipophosphodiesterase C|regulation of lecithinase C activity						rl	2012-04-04T01:19:00Z						biological_process											owl:Class	
GO:1900777	biolink:NamedThing	fumiquinazoline A catabolic process	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline A.	got7fsn_ti	fumiquinazoline A degradation|fumiquinazoline A breakdown|fumiquinazoline A catabolism						di	2012-06-04T09:30:18Z						biological_process											owl:Class	
GO:0044146	biolink:NamedThing	obsolete negative regulation of growth of symbiont involved in interaction with host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.	got7fsn_ti	negative regulation of growth of symbiont during interaction with host				This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-06T02:04:24Z		True				biological_process											owl:Class	
CHEBI:63166	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071338	biolink:NamedThing	positive regulation of hair follicle cell proliferation	Any process that activates or increases the rate or extent of hair follicle cell proliferation.	got7fsn_ti	up regulation of hair follicle cell proliferation|up-regulation of hair follicle cell proliferation|upregulation of hair follicle cell proliferation|activation of hair follicle cell proliferation|stimulation of hair follicle cell proliferation						mah	2009-12-11T11:00:57Z						biological_process											owl:Class	
GO:0140211	biolink:NamedThing	folic acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folic acid(out) + H+(out) = folic acid(in) + H+(in). The main folic acid symporter is the Proton-Coupled Folate Transporter (PCFT/SLC46A1), which has similar affinity for transport of reduced folates (5-methyl THF, 5-formyl THF) and folic acid.	got7fsn_ti							pg	2018-03-30T08:00:09Z				TC:2.A.1.50.1		molecular_function											owl:Class	
GO:2001243	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.	got7fsn_ti	negative regulation of mitochondrial-mediated apoptotic pathway|negative regulation of intrinsic apoptosis|negative regulation of intrinsic apoptotic pathway|negative regulation of intrinsic apoptotic signalling pathway						pr	2011-11-24T01:36:03Z						biological_process											owl:Class	
GO:1901601	biolink:NamedThing	strigolactone biosynthetic process	The chemical reactions and pathways resulting in the formation of strigolactone.	got7fsn_ti	strigolactone synthesis|strigolactone biosynthesis|strigolactone formation|strigolactone anabolism						tb	2012-11-08T01:20:13Z						biological_process											owl:Class	
GO:0043300	biolink:NamedThing	regulation of leukocyte degranulation	Any process that modulates the frequency, rate, or extent of leukocyte degranulation.	got7fsn_ti	regulation of leukocyte granule exocytosis|regulation of immune cell granule exocytosis|regulation of immune cell degranulation|regulation of leucocyte degranulation													biological_process											owl:Class	
GO:1901434	biolink:NamedThing	regulation of toluene catabolic process	Any process that modulates the frequency, rate or extent of toluene catabolic process.	got7fsn_ti	regulation of toluene degradation|regulation of toluene breakdown|regulation of toluene catabolism						tt	2012-10-01T21:12:31Z						biological_process											owl:Class	
GO:0046115	biolink:NamedThing	guanosine catabolic process	The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution.	got7fsn_ti	guanosine degradation|guanosine catabolism|guanosine phosphorolysis|guanosine breakdown										GO:0006160			biological_process											owl:Class	
GO:0007360	biolink:NamedThing	obsolete positive regulation of posterior gap gene transcription	OBSOLETE. The activation of genes encoding transcription factors in the posterior region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila knirps gene.	got7fsn_ti	up-regulation of posterior gap gene transcription|activation of posterior gap gene|stimulation of posterior gap gene transcription|up regulation of posterior gap gene transcription|upregulation of posterior gap gene transcription|activation of posterior gap gene transcription|knirps activation				This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
CHEBI:17522	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071544	biolink:NamedThing	diphosphoinositol polyphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.	got7fsn_ti	diphosphoinositol polyphosphate catabolism|diphosphoinositol polyphosphate degradation|diphosphoinositol polyphosphate breakdown						mah	2010-01-12T05:07:10Z						biological_process											owl:Class	
GO:0002882	biolink:NamedThing	positive regulation of chronic inflammatory response to non-antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.	got7fsn_ti	up-regulation of chronic inflammatory response to non-antigenic stimulus|up regulation of chronic inflammatory response to non-antigenic stimulus|upregulation of chronic inflammatory response to non-antigenic stimulus|activation of chronic inflammatory response to non-antigenic stimulus|stimulation of chronic inflammatory response to non-antigenic stimulus													biological_process											owl:Class	
GO:0000501	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990653	biolink:NamedThing	obsolete monounsaturated fatty acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of a monounsaturated fatty acid. A monounsaturated fatty acid has one double bond in the fatty acid chain with all of the remainder carbon atoms being single-bonded, as opposed to polyunsaturated fatty acids.	got7fsn_ti					For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast.		hjd	2015-02-23T18:59:15Z		True				biological_process											owl:Class	
GO:0019794	biolink:NamedThing	obsolete nonprotein amino acid metabolic process	OBSOLETE. The chemical reactions and pathways involving any amino acid not found, or rarely found, in peptide linkage in proteins.	got7fsn_ti	nonprotein amino acid metabolism|nonprotein amino acid metabolic process			GO:0006520	This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity.					True				biological_process											owl:Class	
GO:0036113	biolink:NamedThing	very long-chain fatty-acyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	got7fsn_ti	very long-chain fatty-acyl-CoA breakdown|very long-chain fatty-acyl-CoA catabolism|very long-chain fatty-acyl-CoA degradation						bf	2012-02-15T11:16:11Z						biological_process											owl:Class	
GO:0046207	biolink:NamedThing	trypanothione catabolic process	The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.	got7fsn_ti	trypanothione catabolism|trypanothione degradation|trypanothione breakdown													biological_process											owl:Class	
CHEBI:26443	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061723	biolink:NamedThing	glycophagy	The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions.	got7fsn_ti							dph	2015-07-08T13:36:51Z						biological_process											owl:Class	
GO:0015319	biolink:NamedThing	sodium:inorganic phosphate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0110133	biolink:NamedThing	negative regulation of CRISPR-cas system	Any process that stops, prevents, or reduces the frequency, rate or extent of a CRISPR-cas system.	got7fsn_ti							kmv	2018-11-14T17:23:07Z						biological_process											owl:Class	
GO:0009135	biolink:NamedThing	purine nucleoside diphosphate metabolic process	The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine nucleoside diphosphate metabolism													biological_process											owl:Class	
GO:1901453	biolink:NamedThing	positive regulation of response to benzene	Any process that activates or increases the frequency, rate or extent of response to benzene.	got7fsn_ti	activation of response to benzene|up regulation of response to benzene|upregulation of response to benzene|up-regulation of response to benzene						tt	2012-10-02T14:20:41Z						biological_process											owl:Class	
GO:1905913	biolink:NamedThing	negative regulation of calcium ion export across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane.	got7fsn_ti	down-regulation of calcium ion efflux from cell|inhibition of calcium ion export from cell|negative regulation of calcium ion efflux from cell|downregulation of calcium ion efflux from cell|down regulation of calcium ion export from cell|down regulation of calcium ion efflux from cell|inhibition of calcium ion efflux from cell|down-regulation of calcium ion export from cell|downregulation of calcium ion export from cell|negative regulation of calcium ion export from cell						rph	2017-02-07T13:20:48Z						biological_process											owl:Class	
GO:0010756	biolink:NamedThing	positive regulation of plasminogen activation	Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.	got7fsn_ti														biological_process											owl:Class	
GO:0052461	biolink:NamedThing	obsolete modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:2000986	biolink:NamedThing	negative regulation of behavioral fear response	Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response.	got7fsn_ti	negative regulation of behavioural fear response						yaf	2011-08-08T09:16:34Z						biological_process											owl:Class	
GO:1905808	biolink:NamedThing	positive regulation of synapse pruning	Any process that activates or increases the frequency, rate or extent of synapse pruning.	got7fsn_ti	regulation of synapse removal|up-regulation of synapse disassembly|upregulation of synapse disassembly|regulation of synapse elimination|activation of synapse disassembly|regulation of synapse disassembly|regulation of synapse clearance|up regulation of synapse disassembly						tb	2017-01-11T22:03:33Z						biological_process											owl:Class	
GO:0110123	biolink:NamedThing	regulation of myotube cell migration	Any process that modulates the frequency, rate or extent of myotube cell migration.	got7fsn_ti							kmv	2018-08-22T21:06:53Z						biological_process											owl:Class	
GO:1902197	biolink:NamedThing	isovaleryl-CoA(4-) biosynthetic process	The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-).	got7fsn_ti	isovaleryl-CoA(4-) formation|isovaleryl-CoA(4-) anabolism|isovaleryl-CoA(4-) synthesis|isovaleryl-CoA(4-) biosynthesis						ms	2013-06-06T09:56:05Z						biological_process											owl:Class	
GO:0050706	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140539	biolink:NamedThing	regulation of melanotic encapsulation of foreign target	Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16749					pg	2020-11-07T08:16:00Z						biological_process											owl:Class	
GO:0033261	biolink:NamedThing	obsolete regulation of S phase	OBSOLETE. A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle.	got7fsn_ti	regulation of S-phase|regulation of S phase|regulation of progression through S phase				This term was made obsolete because cell cycle phases are intervals and so cannot be regulated as such, rather it is the transitions between the phases that are regulated. This term was often also used to annotate genes which should have been annotated to 'regulation of DNA replication', or one of its children.	GO:0044770				True		MetaCyc:SALVADEHYPOX-PWY|MetaCyc:PWY-5043|MetaCyc:SALVPURINE2-PWY		biological_process											owl:Class	
GO:1900910	biolink:NamedThing	positive regulation of olefin metabolic process	Any process that activates or increases the frequency, rate or extent of olefin metabolic process.	got7fsn_ti	activation of olefin metabolism|up-regulation of olefin metabolism|activation of olefin metabolic process|upregulation of olefin metabolism|up regulation of olefin metabolism|positive regulation of olefin metabolism|up regulation of olefin metabolic process|upregulation of olefin metabolic process|up-regulation of olefin metabolic process						tt	2012-06-13T04:18:58Z						biological_process											owl:Class	
GO:0098891	biolink:NamedThing	extrinsic component of presynaptic active zone membrane	The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0062125	biolink:NamedThing	regulation of mitochondrial gene expression	Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA).	got7fsn_ti							dph	2019-05-30T16:45:04Z						biological_process											owl:Class	
GO:0004217	biolink:NamedThing	obsolete cathepsin L activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity towards protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.	got7fsn_ti	Aldrichina grahami cysteine proteinase|cathepsin L activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0052584	biolink:NamedThing	obsolete oxidoreductase activity, acting on halogen in donors, with NAD or NADP as acceptor	OBSOLETE. Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces NAD or NADP.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20613			This term was obsoleted because EC obsoleted it, and there was no other evidence that this function exists.		ai	2010-08-13T10:17:56Z		True		EC:1.22.1.-		molecular_function											owl:Class	
GO:0010823	biolink:NamedThing	negative regulation of mitochondrion organization	Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.	got7fsn_ti	negative regulation of mitochondrion organisation													biological_process											owl:Class	
GO:0051408	biolink:NamedThing	glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out).	got7fsn_ti														molecular_function											owl:Class	
GO:1900151	biolink:NamedThing	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.	got7fsn_ti	regulation of mRNA catabolism, deadenylylation-dependent|regulation of mRNA breakdown, deadenylation-dependent decay|regulation of mRNA catabolic process, deadenylylation-dependent|regulation of mRNA degradation, deadenylation-dependent decay|regulation of deadenylation-dependent mRNA decay|regulation of mRNA catabolism, deadenylation-dependent|regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|regulation of mRNA catabolic process, deadenylation-dependent						bf	2012-03-07T09:14:43Z						biological_process											owl:Class	
GO:1900373	biolink:NamedThing	positive regulation of purine nucleotide biosynthetic process	Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.	got7fsn_ti	up regulation of purine nucleotide biosynthetic process|positive regulation of purine nucleotide anabolism|up-regulation of purine nucleotide biosynthetic process|up-regulation of purine nucleotide anabolism|up-regulation of purine nucleotide formation|positive regulation of purine nucleotide formation|upregulation of purine nucleotide biosynthetic process|positive regulation of purine nucleotide biosynthesis|up regulation of purine nucleotide formation|up-regulation of purine nucleotide synthesis|activation of purine nucleotide formation|up regulation of purine nucleotide anabolism|up regulation of purine nucleotide biosynthesis|activation of purine nucleotide biosynthetic process|upregulation of purine nucleotide biosynthesis|activation of purine nucleotide biosynthesis|up regulation of purine nucleotide synthesis|up-regulation of purine nucleotide biosynthesis|activation of purine nucleotide synthesis|activation of purine nucleotide anabolism|upregulation of purine nucleotide anabolism|upregulation of purine nucleotide synthesis|positive regulation of purine nucleotide synthesis|upregulation of purine nucleotide formation						krc	2012-04-17T12:32:37Z						biological_process											owl:Class	
GO:1900246	biolink:NamedThing	positive regulation of RIG-I signaling pathway	Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway.	got7fsn_ti	upregulation of retinoic acid inducible gene I signaling pathway|up-regulation of DDX58 signaling pathway|activation of retinoic acid inducible gene I signaling pathway|up-regulation of retinoic acid inducible gene I signaling pathway|activation of RIG-I signaling pathway|up regulation of retinoic acid inducible gene I signaling pathway|up regulation of DDX58 signaling pathway|activation of DDX58 signaling pathway|upregulation of DDX58 signaling pathway|up regulation of RIG-I signaling pathway|up-regulation of RIG-I signaling pathway|positive regulation of retinoic acid inducible gene I signaling pathway|positive regulation of DDX58 signaling pathway|positive regulation of RIG-I signalling pathway|upregulation of RIG-I signaling pathway						ss	2012-04-02T11:00:28Z						biological_process											owl:Class	
GO:0051257	biolink:NamedThing	meiotic spindle midzone assembly	The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.	got7fsn_ti	spindle midzone biosynthesis involved in meiosis|spindle midzone biogenesis involved in meiosis|meiotic spindle midzone formation|meiotic spindle midzone biogenesis|meiotic spindle midzone biosynthesis|spindle midzone assembly involved in meiosis|spindle midzone formation involved in meiosis													biological_process											owl:Class	
CHEBI:58228	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075079	biolink:NamedThing	obsolete positive regulation by host of symbiont receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0036041	biolink:NamedThing	long-chain fatty acid binding	Binding to a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	long chain fatty acid binding						bf	2011-11-24T02:54:39Z						molecular_function											owl:Class	
GO:0007574	biolink:NamedThing	obsolete cell aging (sensu Saccharomyces)	OBSOLETE. Process associated with continued cell division (budding) by the mother cell. Age is often measured by counting the number of bud scars on the cell.	got7fsn_ti	cell aging (sensu Saccharomyces)			GO:0007569	This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'.					True				biological_process											owl:Class	
GO:2000978	biolink:NamedThing	negative regulation of forebrain neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.	got7fsn_ti							yaf	2011-08-03T12:09:16Z						biological_process											owl:Class	
GO:0016284	biolink:NamedThing	obsolete alanine aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from an oligopeptide or polypeptide.	got7fsn_ti	alanine aminopeptidase activity				This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.	GO:0004177|GO:0008235				True		EC:3.4.11.-		molecular_function											owl:Class	
GO:0045590	biolink:NamedThing	negative regulation of regulatory T cell differentiation	Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.	got7fsn_ti	down-regulation of regulatory T cell differentiation|negative regulation of regulatory T-lymphocyte differentiation|downregulation of regulatory T cell differentiation|down regulation of regulatory T cell differentiation|negative regulation of suppressor T cell differentiation|inhibition of regulatory T cell differentiation|negative regulation of suppressor T-cell differentiation|negative regulation of regulatory T-cell differentiation|negative regulation of regulatory T lymphocyte differentiation|negative regulation of regulatory T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0044251	biolink:NamedThing	obsolete protein catabolic process by pepsin	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid).	got7fsn_ti	protein degradation by pepsin|protein breakdown by pepsin				The reason for obsoletion is that this term represents a specific gene product.	GO:0030163				True				biological_process											owl:Class	
GO:2000288	biolink:NamedThing	positive regulation of myoblast proliferation	Any process that activates or increases the frequency, rate or extent of myoblast proliferation.	got7fsn_ti							rl	2010-12-16T05:20:52Z						biological_process											owl:Class	
CHEBI:63738	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001172	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034332	biolink:NamedThing	adherens junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	got7fsn_ti	adherens junction organisation													biological_process											owl:Class	
GO:0110077	biolink:NamedThing	vesicle-mediated intercellular transport	A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.	got7fsn_ti							kmv	2018-01-29T14:46:52Z						biological_process											owl:Class	
GO:0035376	biolink:NamedThing	sterol import	The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti	sterol influx|sterol uptake						bf	2010-03-18T10:53:01Z						biological_process											owl:Class	
GO:2000537	biolink:NamedThing	regulation of B cell chemotaxis	Any process that modulates the frequency, rate or extent of B cell chemotaxis.	got7fsn_ti							ebc	2011-03-29T09:49:25Z						biological_process											owl:Class	
GO:0061597	biolink:NamedThing	obsolete cyclic pyranopterin monophosphate synthase activity	OBSOLETE. Catalysis of the reaction GTP = cyclic pyranopterin phosphate + diphosphate.	got7fsn_ti					This term was made obsolete because it represents two distinct molecular functions.		dph	2014-02-10T13:54:19Z		True				molecular_function											owl:Class	
GO:0001047	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010758	biolink:NamedThing	regulation of macrophage chemotaxis	Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
UBERON:0000993	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903970	biolink:NamedThing	negative regulation of response to macrophage colony-stimulating factor	Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor.	got7fsn_ti	negative regulation of response to M-CSF|down-regulation of response to macrophage colony-stimulating factor|inhibition of response to M-CSF|downregulation of response to M-CSF|down-regulation of response to M-CSF|down regulation of response to M-CSF|down-regulation of response to macrophage colony-stimulating factor stimulus|downregulation of response to macrophage colony-stimulating factor stimulus|downregulation of response to macrophage colony-stimulating factor|down regulation of response to macrophage colony-stimulating factor|negative regulation of response to macrophage colony-stimulating factor|down regulation of response to macrophage colony-stimulating factor stimulus|inhibition of response to macrophage colony-stimulating factor stimulus|negative regulation of response to macrophage colony-stimulating factor stimulus|inhibition of response to macrophage colony-stimulating factor						nc	2015-03-02T14:41:08Z						biological_process											owl:Class	
GO:1905962	biolink:NamedThing	glutamatergic neuron differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron.	got7fsn_ti							sl	2017-02-23T17:40:43Z						biological_process											owl:Class	
GO:0048351	biolink:NamedThing	negative regulation of paraxial mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification.	got7fsn_ti	inhibition of paraxial mesodermal cell fate specification|downregulation of paraxial mesodermal cell fate specification|down-regulation of paraxial mesodermal cell fate specification|down regulation of paraxial mesodermal cell fate specification													biological_process											owl:Class	
GO:0033346	biolink:NamedThing	asparagine catabolic process via 2-oxosuccinamate	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate.	got7fsn_ti												MetaCyc:PWY-4002		biological_process											owl:Class	
GO:1904701	biolink:NamedThing	Wnt-Frizzled-LRP5/6 complex assembly	The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex.	got7fsn_ti	Wnt receptor complex assembly|WNT-FZD-LRP5 complex formation|Wnt-induced Frizzled-LRP5/6 complex assembly|Wnt-induced Frizzled-LRP5/6 complex formation|WNT-FZD-LRP6 complex formation|WNT-FZD-LRP6 complex assembly|Frizzled-LRP5/6 complex formation|WNT-FZD-LRP5 complex assembly|Wnt-FZD-LRP5/6 trimeric complex assembly|Frizzled-LRP5/6 complex assembly|Wnt-FZD-LRP5/6 trimeric complex formation						bf	2015-10-01T09:37:57Z						biological_process											owl:Class	
GO:0044673	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex	A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420.	got7fsn_ti	FO-synthase complex						jl	2012-08-09T10:49:05Z						cellular_component											owl:Class	
GO:1901145	biolink:NamedThing	mesenchymal cell apoptotic process involved in nephron morphogenesis	Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis.	got7fsn_ti							pr	2012-07-13T01:43:51Z						biological_process											owl:Class	
CHEBI:58130	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006292	biolink:NamedThing	obsolete pyrimidine-dimer repair, DNA damage recognition	OBSOLETE. The location of pyrimidine dimers by a large multienzyme complex that scans the DNA for distortions in the double helix caused by pyrimidine dimers.	got7fsn_ti	pyrimidine-dimer repair, DNA damage recognition				This term was made obsolete because it is a substrate specific DNA repair process.	GO:0000715|GO:0000716				True				biological_process											owl:Class	
GO:0070352	biolink:NamedThing	positive regulation of white fat cell proliferation	Any process that activates or increases the rate or extent of white fat cell proliferation.	got7fsn_ti	up regulation of white fat cell proliferation|positive regulation of white adipocyte proliferation|upregulation of white fat cell proliferation|up-regulation of white fat cell proliferation|positive regulation of white adipose cell proliferation|activation of white fat cell proliferation|stimulation of white fat cell proliferation													biological_process											owl:Class	
GO:1902011	biolink:NamedThing	poly(ribitol phosphate) teichoic acid metabolic process	The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid.	got7fsn_ti	poly(ribitol phosphate) teichoic acid metabolism						tb	2013-03-22T15:43:36Z						biological_process											owl:Class	
GO:1900346	biolink:NamedThing	negative regulation of methane biosynthetic process from methanethiol	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol.	got7fsn_ti	inhibition of methane biosynthetic process from methanethiol|downregulation of methane biosynthetic process from methanethiol|down-regulation of methane biosynthetic process from methanethiol|down regulation of methane biosynthetic process from methanethiol						tt	2012-04-06T02:09:58Z						biological_process											owl:Class	
GO:0034651	biolink:NamedThing	cortisol biosynthetic process	The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.	got7fsn_ti	cortisol biosynthesis|cortisol synthesis|cortisol anabolism|cortisol formation													biological_process											owl:Class	
GO:0060341	biolink:NamedThing	regulation of cellular localization	Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.	got7fsn_ti	regulation of cellular localisation													biological_process											owl:Class	
GO:0019352	biolink:NamedThing	protoporphyrinogen IX biosynthetic process from glycine	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine.	got7fsn_ti	protoporphyrinogen IX synthesis from glycine|protoporphyrinogen IX formation from glycine|protoporphyrinogen IX anabolism from glycine													biological_process											owl:Class	
GO:0006161	biolink:NamedThing	deoxyguanosine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.	got7fsn_ti	deoxyguanosine degradation|deoxyguanosine breakdown|deoxyguanosine catabolism													biological_process											owl:Class	
GO:1905191	biolink:NamedThing	positive regulation of metaphase/anaphase transition of meiosis II	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II.	got7fsn_ti	positive regulation of meiosis II metaphase/anaphase transition						vw	2016-05-10T16:47:05Z						biological_process											owl:Class	
GO:1903677	biolink:NamedThing	regulation of cap-independent translational initiation	Any process that modulates the frequency, rate or extent of cap-independent translational initiation.	got7fsn_ti							bf	2014-11-27T19:52:20Z						biological_process											owl:Class	
GO:0006054	biolink:NamedThing	N-acetylneuraminate metabolic process	The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.	got7fsn_ti	N-acetylneuraminate metabolism|sialic acid metabolism|sialic acid metabolic process													biological_process											owl:Class	
GO:2001220	biolink:NamedThing	obsolete negative regulation of G2 phase of mitotic cell cycle	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of G2 phase of mitotic cell cycle.	got7fsn_ti	negative regulation of G2 phase of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.		yaf	2011-11-17T03:28:44Z		True				biological_process											owl:Class	
GO:1902205	biolink:NamedThing	regulation of interleukin-2-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway.	got7fsn_ti	regulation of interleukin-2-mediated signalling pathway|regulation of IL-2-mediated signaling pathway						lb	2013-06-11T07:34:39Z						biological_process											owl:Class	
GO:0018949	biolink:NamedThing	m-xylene metabolic process	The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	meta-xylene metabolism|meta-xylene metabolic process|m-xylene metabolism											UM-BBD_pathwayID:mxy		biological_process											owl:Class	
GO:1990558	biolink:NamedThing	mitochondrial malonate(1-) transmembrane transport	The process in which malonate(1-) is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:52:43Z						biological_process											owl:Class	
GO:0035817	biolink:NamedThing	renal sodium ion absorption involved in negative regulation of renal sodium excretion	Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time.	got7fsn_ti							bf	2011-04-20T01:40:11Z						biological_process											owl:Class	
GO:0005430	biolink:NamedThing	obsolete synaptic vesicle amine transmembrane transporter activity	OBSOLETE. Enables the transfer of amines across synaptic vesicle membranes.	got7fsn_ti					The class was obsoleted because the cellular location of a function should not be part of the class label.	GO:0005275				True				molecular_function											owl:Class	
GO:2001167	biolink:NamedThing	negative regulation of histone H2B ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B ubiquitination.	got7fsn_ti							se	2011-10-25T10:49:56Z						biological_process											owl:Class	
GO:0019066	biolink:NamedThing	obsolete translocation of virus into host cell	OBSOLETE. The translocation of an entire virus particle across the host cell plasma membrane.	got7fsn_ti	translocation of virus into host cell|viral translocation			GO:0046718	This term was made obsolete because it is ambiguous, and more specific terms have been created.					True				biological_process											owl:Class	
GO:1901043	biolink:NamedThing	obsolete protein polyubiquitination involved in cellular response to misfolded protein	OBSOLETE. Any protein polyubiquitination that is involved in cellular response to misfolded protein.	got7fsn_ti	protein polyubiquitination involved in cellular response to misfolded protein|protein polyubiquitylation of cellular response to misfolded protein|polyubiquitin of cellular response to misfolded protein|protein polyubiquitination of cellular response to misfolded protein|protein polyubiquitinylation of cellular response to misfolded protein				This term was made obsolete because it was added in error and a more specific term was created.	GO:1901044	al	2012-06-26T09:40:45Z		True				biological_process											owl:Class	
GO:0140345	biolink:NamedThing	phosphatidylcholine flippase activity	Catalysis of the movement of phosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	phosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet)						pg	2019-05-16T13:43:47Z						molecular_function											owl:Class	
GO:0033140	biolink:NamedThing	negative regulation of peptidyl-serine phosphorylation of STAT protein	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	got7fsn_ti	down regulation of serine phosphorylation of STAT3 protein|negative regulation of serine phosphorylation of STAT3 protein|down-regulation of serine phosphorylation of STAT3 protein|inhibition of serine phosphorylation of STAT3 protein|downregulation of serine phosphorylation of STAT3 protein										GO:1903262			biological_process											owl:Class	
GO:1902334	biolink:NamedThing	fructose export from vacuole to cytoplasm	The directed movement of fructose from vacuole to cytoplasm.	got7fsn_ti	fructose transport from vacuole to cytoplasm						tb	2013-07-26T22:18:12Z						biological_process											owl:Class	
GO:0008051	biolink:NamedThing	obsolete farnesyl-diphosphate farnesyl transferase complex	OBSOLETE. A complex that possesses farnesyl-diphosphate farnesyl transferase activity.	got7fsn_ti	farnesyl-diphosphate farnesyl transferase complex				This term was made obsolete because there is no evidence that this enzyme ever exists as anything other than a monomer.	GO:0004310				True				cellular_component											owl:Class	
GO:1904285	biolink:NamedThing	regulation of protein-pyridoxal-5-phosphate linkage	Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.	got7fsn_ti							mcc	2015-06-05T17:21:14Z						biological_process											owl:Class	
GO:1902824	biolink:NamedThing	positive regulation of late endosome to lysosome transport	Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport.	got7fsn_ti	up regulation of late endosome to lysosome transport|activation of late endosome to lysosome transport|up-regulation of late endosome to lysosome transport|upregulation of late endosome to lysosome transport						pad	2014-03-31T10:08:57Z						biological_process											owl:Class	
GO:0002656	biolink:NamedThing	negative regulation of tolerance induction to nonself antigen	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen.	got7fsn_ti	down regulation of tolerance induction to nonself antigen|inhibition of tolerance induction to nonself antigen|downregulation of tolerance induction to nonself antigen|down-regulation of tolerance induction to nonself antigen													biological_process											owl:Class	
GO:0042429	biolink:NamedThing	serotonin catabolic process	The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	got7fsn_ti	serotonin degradation|serotonin catabolism|serotonin breakdown													biological_process											owl:Class	
GO:1900643	biolink:NamedThing	regulation of chanoclavine-I biosynthetic process	Any process that modulates the frequency, rate or extent of chanoclavine-I biosynthetic process.	got7fsn_ti	regulation of chanoclavine-I formation|regulation of chanoclavine-I anabolism|regulation of chanoclavine-I synthesis|regulation of chanoclavine-I biosynthesis						di	2012-05-22T04:03:08Z						biological_process											owl:Class	
GO:0010524	biolink:NamedThing	positive regulation of calcium ion transport into cytosol	Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.	got7fsn_ti														biological_process											owl:Class	
GO:2000136	biolink:NamedThing	regulation of cell proliferation involved in heart morphogenesis	Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.	got7fsn_ti							dph	2010-09-29T12:43:53Z						biological_process											owl:Class	
GO:0032122	biolink:NamedThing	oral apparatus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans.	got7fsn_ti	oral apparatus morphogenesis|stomatogenesis|oral apparatus organization and biogenesis|oral apparatus organisation													biological_process											owl:Class	
GO:1901582	biolink:NamedThing	positive regulation of telomeric RNA transcription from RNA pol II promoter	Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.	got7fsn_ti	upregulation of telomeric RNA transcription from Pol II promoter|up regulation of telomeric RNA transcription from RNA pol II promoter|up regulation of telomeric RNA transcription from Pol II promoter|upregulation of telomeric RNA transcription from RNA pol II promoter|positive regulation of telomeric RNA transcription from Pol II promoter|activation of telomeric RNA transcription from Pol II promoter|up-regulation of telomeric RNA transcription from RNA pol II promoter|activation of telomeric RNA transcription from RNA pol II promoter|up-regulation of telomeric RNA transcription from Pol II promoter						al	2012-11-06T11:07:25Z						biological_process											owl:Class	
GO:1900932	biolink:NamedThing	regulation of nonadec-1-ene metabolic process	Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process.	got7fsn_ti	regulation of nonadec-1-ene metabolism						tt	2012-06-14T03:11:28Z						biological_process											owl:Class	
GO:0002883	biolink:NamedThing	regulation of hypersensitivity	Any process that modulates the frequency, rate, or extent of hypersensitivity.	got7fsn_ti														biological_process											owl:Class	
GO:1905089	biolink:NamedThing	regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization.	got7fsn_ti	regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization						pad	2016-03-30T15:34:29Z						biological_process											owl:Class	
GO:0019277	biolink:NamedThing	UDP-N-acetylgalactosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-N-acetylgalactosamine biosynthesis|UDP-N-acetylgalactosamine formation|UDP-N-acetylgalactosamine anabolism|UDP-N-acetylgalactosamine synthesis											MetaCyc:UDPNACETYLGALSYN-PWY		biological_process											owl:Class	
GO:0106120	biolink:NamedThing	positive regulation of sterol biosynthetic process	Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process.	got7fsn_ti							hjd	2018-04-19T17:48:21Z						biological_process											owl:Class	
GO:1901828	biolink:NamedThing	zeaxanthin bis(beta-D-glucoside) metabolic process	The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).	got7fsn_ti	zeaxanthin diglucoside metabolism|zeaxanthin bis(beta-D-glucoside) metabolism						yaf	2013-01-22T12:31:56Z						biological_process											owl:Class	
GO:0052364	biolink:NamedThing	obsolete catabolism by host of substance in symbiont	OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont resulting in the breakdown of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1901805	biolink:NamedThing	beta-glucoside catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-glucoside.	got7fsn_ti	beta-glucoside degradation|beta-glucoside catabolism|beta-glucoside breakdown						yaf	2013-01-22T10:10:26Z						biological_process											owl:Class	
GO:0045711	biolink:NamedThing	positive regulation of adult salivary gland boundary specification	Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism.	got7fsn_ti	up regulation of adult salivary gland determination|positive regulation of adult salivary gland determination|stimulation of adult salivary gland determination|upregulation of adult salivary gland determination|activation of adult salivary gland determination|up-regulation of adult salivary gland determination													biological_process											owl:Class	
GO:0061306	biolink:NamedThing	obsolete DNA strand renaturation involved in double-strand break repair	OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14671			This term was obsoleted because it represents a molecular function.	GO:0006302|GO:0036310	dph	2010-09-21T09:36:47Z		True				biological_process											owl:Class	
GO:0002189	biolink:NamedThing	ribose phosphate diphosphokinase complex	A protein complex having ribose phosphate diphosphokinase activity.	got7fsn_ti	phosphoribosylpyrophosphate synthetase complex|PRPP synthetase complex				In mammals, the complex consists of two non-identical catalytic subunits and two non-identical regulatory subunits.		hjd	2011-06-27T02:49:33Z						cellular_component											owl:Class	
GO:0090149	biolink:NamedThing	mitochondrial membrane fission	A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission.	got7fsn_ti	membrane fission involved in mitochondrial fission|mitochondrial membrane scission						tb	2009-12-08T03:08:57Z						biological_process											owl:Class	
GO:2000817	biolink:NamedThing	regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore	Any regulation of histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore.	got7fsn_ti	regulation of histone H3-T3 phosphorylation involved in CPC complex localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in CPC localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in chromosomal passenger complex localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localisation to kinetochore						mah	2011-07-12T11:37:40Z						biological_process											owl:Class	
GO:0071582	biolink:NamedThing	negative regulation of zinc ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							mah	2010-01-28T03:14:25Z						biological_process											owl:Class	
GO:0075178	biolink:NamedThing	obsolete positive regulation of calcium or calmodulin-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|positive regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1905678	biolink:NamedThing	negative regulation of adaptive immune effector response	Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response.	got7fsn_ti	downregulation of adaptive immune effector response|down-regulation of adaptive immune effector response|inhibition of adaptive immune effector response|down regulation of adaptive immune effector response						tb	2016-11-11T22:25:05Z						biological_process											owl:Class	
GO:0044007	biolink:NamedThing	obsolete dissemination or transmission of symbiont from host	OBSOLETE. The movement of an organism from a host to another host or from a host to another place in the environment. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	dissemination or transmission of organism from host				This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.					True				biological_process											owl:Class	
GO:0030831	biolink:NamedThing	obsolete positive regulation of cGMP catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.	got7fsn_ti	positive regulation of cGMP catabolism|stimulation of cGMP catabolic process|up regulation of cGMP catabolic process|positive regulation of cGMP breakdown|positive regulation of cGMP degradation|upregulation of cGMP catabolic process|up-regulation of cGMP catabolic process|activation of cGMP catabolic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:1900158	biolink:NamedThing	negative regulation of bone mineralization involved in bone maturation	Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation.	got7fsn_ti	downregulation of bone mineralization involved in bone maturation|down regulation of bone mineralization involved in bone maturation|inhibition of bone mineralization involved in bone maturation|down-regulation of bone mineralization involved in bone maturation						vk	2012-03-07T08:55:12Z						biological_process											owl:Class	
GO:0009475	biolink:NamedThing	obsolete high-molecular-weight cytochrome c (hexadecaheme)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	high-molecular-weight cytochrome c (hexadecaheme)				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:1901751	biolink:NamedThing	leukotriene A4 metabolic process	The chemical reactions and pathways involving leukotriene A4.	got7fsn_ti	leukotriene A4 metabolism						yaf	2013-01-14T11:04:56Z						biological_process											owl:Class	
GO:0140340	biolink:NamedThing	cerebroside transfer activity	Directly binding to a cerebroside and delivering it either to an acceptor molecule or to a specific location.	got7fsn_ti	cerebroside carrier activity						pg	2019-05-16T11:37:31Z						molecular_function											owl:Class	
GO:0060980	biolink:NamedThing	cell migration involved in coronary vasculogenesis	The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.	got7fsn_ti							dph	2009-10-06T02:33:06Z						biological_process											owl:Class	
GO:0046281	biolink:NamedThing	cinnamic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid.	got7fsn_ti	phenylacrylic acid catabolic process|cinnamylic acid catabolism|cinnamic acid degradation|cinnamic acid breakdown|cinnamic acid catabolism|cinnamylic acid catabolic process|phenylacrylic acid catabolism													biological_process											owl:Class	
GO:0052404	biolink:NamedThing	obsolete negative regulation by host of symbiont peptidase activity	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition of symbiont protease activity|down-regulation by host of symbiont protease activity|down regulation by host of symbiont protease activity|inhibition by host of symbiont protease activity|negative regulation by host of symbiont protease activity|downregulation by host of symbiont protease activity	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0015461	biolink:NamedThing	obsolete endosomal oligosaccharide transporter	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	endosomal oligosaccharide transporter				This term was made obsolete because it contains both component and function information.	GO:0005768|GO:0015157				True				molecular_function											owl:Class	
GO:0004682	biolink:NamedThing	obsolete protein kinase CK2 activity	OBSOLETE. Catalysis of the reaction: casein + ATP = phosphocasein + ADP.	got7fsn_ti	casein kinase II, catalytic activity|casein kinase II activity|protein kinase CK2, intrinsic catalyst activity|protein kinase CK2 activity			GO:0004674	This term was made obsolete because it represents a gene product.					True	GO:0008604			molecular_function											owl:Class	
GO:0031611	biolink:NamedThing	obsolete ER proteasome regulatory particle, base subcomplex	OBSOLETE. The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the endoplasmic reticulum of a cell.	got7fsn_ti					This term was made obsolete because there is no evidence in the literature of its existence.					True				cellular_component											owl:Class	
GO:2000361	biolink:NamedThing	regulation of prostaglandin-E synthase activity	Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity.	got7fsn_ti	regulation of prostaglandin H-E isomerase activity|regulation of endoperoxide isomerase activity|regulation of prostaglandin endoperoxide E2 isomerase activity|regulation of PGE isomerase activity|regulation of prostaglandin R-prostaglandin E isomerase activity|regulation of prostaglandin endoperoxide E isomerase activity|regulation of PGH-PGE isomerase activity|regulation of prostaglandin-H2 E-isomerase activity|regulation of PGE2 isomerase activity|regulation of Prostaglandin-H(2) E-isomerase activity|regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity						bf	2011-02-03T04:05:35Z						biological_process											owl:Class	
GO:1902656	biolink:NamedThing	calcium ion import into cytosol	The directed movement of calcium ion into a cytosol.	got7fsn_ti	calcium import into cytosol						pr	2014-01-22T13:41:11Z						biological_process											owl:Class	
PR:000022358	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902348	biolink:NamedThing	cellular response to strigolactone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.	got7fsn_ti	cellular response to strigolactone analog GR24						dhl	2013-08-08T18:45:05Z						biological_process											owl:Class	
GO:1903566	biolink:NamedThing	positive regulation of protein localization to cilium	Any process that activates or increases the frequency, rate or extent of protein localization to cilium.	got7fsn_ti	upregulation of protein localization to cilium|up regulation of protein localization to cilium|up-regulation of protein localization to cilium|activation of protein localization to cilium						krc	2014-10-24T20:58:28Z						biological_process											owl:Class	
GO:1905193	biolink:NamedThing	negative regulation of chloroplast fission	Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission.	got7fsn_ti	down-regulation of chloroplast fission|down-regulation of chloroplast division|negative regulation of chloroplast division|down regulation of chloroplast division|down regulation of chloroplast fission|inhibition of chloroplast division|inhibition of chloroplast fission|downregulation of chloroplast division|downregulation of chloroplast fission				Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments.		lr	2016-05-10T19:07:43Z						biological_process											owl:Class	
GO:0010670	biolink:NamedThing	obsolete positive regulation of oxygen and reactive oxygen species metabolic process	OBSOLETE. Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).	got7fsn_ti	positive regulation of oxygen and reactive oxygen species metabolic process				This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together.	GO:2000376|GO:2000379				True				biological_process											owl:Class	
GO:0030887	biolink:NamedThing	positive regulation of myeloid dendritic cell activation	Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation.	got7fsn_ti	activation of myeloid dendritic cell activation|up-regulation of myeloid dendritic cell activation|up regulation of myeloid dendritic cell activation|stimulation of myeloid dendritic cell activation|upregulation of myeloid dendritic cell activation													biological_process											owl:Class	
GO:0007235	biolink:NamedThing	obsolete activation of Ypd1 protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of Ypd1 protein				This term was made obsolete because it contains gene product and species specific information.					True				biological_process											owl:Class	
GO:0016970	biolink:NamedThing	obsolete hemocyanin	OBSOLETE. A blue, copper-containing oxygen carrier present in many molluscs and arthropods.	got7fsn_ti	hemocyanin			GO:0005344	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1904989	biolink:NamedThing	positive regulation of endothelial cell activation	Any process that activates or increases the frequency, rate or extent of endothelial cell activation.	got7fsn_ti	up regulation of endothelial cell activation|upregulation of endothelial cell activation|up-regulation of endothelial cell activation|activation of endothelial cell activation						bc	2016-02-29T16:16:25Z						biological_process											owl:Class	
GO:1904177	biolink:NamedThing	regulation of adipose tissue development	Any process that modulates the frequency, rate or extent of adipose tissue development.	got7fsn_ti	regulation of adipogenesis						sl	2015-04-29T20:01:01Z						biological_process											owl:Class	
GO:0052190	biolink:NamedThing	obsolete modulation by symbiont of host phagocytosis	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18562			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1900065	biolink:NamedThing	regulation of ethanol catabolic process	Any process that modulates the frequency, rate or extent of ethanol catabolic process.	got7fsn_ti	regulation of ethanol catabolism|regulation of ethanol breakdown|regulation of ethanol degradation						dph	2012-01-26T01:51:40Z						biological_process											owl:Class	
GO:0032335	biolink:NamedThing	regulation of activin secretion	Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0039559	biolink:NamedThing	obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7) by promoting the ubiquitin-dependent degradation of IRF7, mediated by the proteasome.	got7fsn_ti	promotion by virus of proteosome-dependent IRF7 degradation				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-09T04:38:58Z		True				biological_process											owl:Class	
GO:0050696	biolink:NamedThing	trichloroethylene catabolic process	The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.	got7fsn_ti	trichloroethylene catabolism|trichloroethylene degradation|trichloroethene catabolic process|trichloroethylene breakdown|trichloroethene catabolism													biological_process											owl:Class	
GO:2000311	biolink:NamedThing	regulation of AMPA receptor activity	Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.	got7fsn_ti	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity						bf	2011-01-18T10:10:28Z						biological_process											owl:Class	
GO:0002601	biolink:NamedThing	regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.	got7fsn_ti	regulation of polysaccharide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:1901333	biolink:NamedThing	positive regulation of lateral root development	Any process that activates or increases the frequency, rate or extent of lateral root development.	got7fsn_ti	up regulation of lateral root development|up-regulation of lateral root development|activation of lateral root development|upregulation of lateral root development						tb	2012-09-01T00:59:46Z						biological_process											owl:Class	
GO:0032361	biolink:NamedThing	pyridoxal phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.	got7fsn_ti														biological_process											owl:Class	
GO:0019830	biolink:NamedThing	obsolete cadmium sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cadmium sensitivity/resistance			GO:0046686	This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0018183	biolink:NamedThing	obsolete enzyme active site formation via S-selenyl-L-cysteine	OBSOLETE. The transient selenylation of peptidyl-cysteine to form S-selenyl-L-cysteine.	got7fsn_ti	enzyme active site formation via S-selenyl-L-cysteine				This term was made obsolete because this structure does not exist.					True				biological_process											owl:Class	
GO:1901789	biolink:NamedThing	benzoyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of benzoyl-CoA.	got7fsn_ti	benzoyl-CoA biosynthesis|benzoyl-CoA anabolism|benzoyl-CoA formation|benzoyl-CoA synthesis						yaf	2013-01-16T11:14:03Z						biological_process											owl:Class	
GO:0070832	biolink:NamedThing	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline	The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.	got7fsn_ti							mah	2009-07-29T03:49:14Z				MetaCyc:PWY4FS-2		biological_process											owl:Class	
GO:2000955	biolink:NamedThing	negative regulation of cyclodextrin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin metabolic process.	got7fsn_ti	negative regulation of cyclodextrin metabolism						tt	2011-08-01T02:22:05Z						biological_process											owl:Class	
GO:2001226	biolink:NamedThing	negative regulation of chloride transport	Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport.	got7fsn_ti							dph	2011-11-18T05:46:03Z						biological_process											owl:Class	
GO:2000440	biolink:NamedThing	regulation of toll-like receptor 15 signaling pathway	Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway.	got7fsn_ti	regulation of TLR15 signaling pathway|regulation of toll-like receptor 15 signalling pathway						bf	2011-03-04T10:28:24Z						biological_process											owl:Class	
GO:2000358	biolink:NamedThing	positive regulation of kidney smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation.	got7fsn_ti							yaf	2011-02-03T02:14:31Z						biological_process											owl:Class	
GO:0048300	biolink:NamedThing	negative regulation of isotype switching to IgD isotypes	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes.	got7fsn_ti	inhibition of isotype switching to IgD isotypes|negative regulation of class switching to IgD isotypes|downregulation of isotype switching to IgD isotypes|down-regulation of isotype switching to IgD isotypes|negative regulation of class switch recombination to IgD isotypes|down regulation of isotype switching to IgD isotypes|negative regulation of isotype switch recombination to IgD isotypes													biological_process											owl:Class	
GO:0009204	biolink:NamedThing	deoxyribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	deoxyribonucleoside triphosphate catabolism|deoxyribonucleoside triphosphate breakdown|deoxyribonucleoside triphosphate degradation													biological_process											owl:Class	
GO:0052511	biolink:NamedThing	obsolete positive regulation by organism of symbiont ethylene-mediated defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of symbiont ethylene-mediated defense response|positive regulation by organism of symbiont ethylene-mediated defense response|induction by organism of symbiont ethylene-mediated defense response|upregulation by organism of symbiont ethylene-mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0023070	biolink:NamedThing	obsolete signal transmission via air	OBSOLETE. The process in which a signal is conveyed via the air.	got7fsn_ti	signal transmission via air				This term was made obsolete because the meaning of the term is ambiguous.			2010-02-16T09:30:50Z		True				biological_process											owl:Class	
CHEBI:15035	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048074	biolink:NamedThing	negative regulation of eye pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.	got7fsn_ti	inhibition of eye pigmentation|downregulation of eye pigmentation|down regulation of eye pigmentation|down-regulation of eye pigmentation													biological_process											owl:Class	
GO:1901314	biolink:NamedThing	regulation of histone H2A K63-linked ubiquitination	Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination.	got7fsn_ti							tb	2012-08-22T20:29:04Z						biological_process											owl:Class	
GO:0004250	biolink:NamedThing	obsolete aminopeptidase I activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates.	got7fsn_ti	leucine aminopeptidase IV activity|yeast aminopeptidase I|aminopeptidase yscI activity|vacuolar aminopeptidase I activity|aminopeptidase III activity|aminopeptidase I activity				This term was made obsolete because it represents a gene product.	GO:0008235|GO:0004177				True		MetaCyc:3.4.11.22-RXN|EC:3.4.11.22		molecular_function											owl:Class	
CL:0000158	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120254	biolink:NamedThing	olefinic compound metabolic process	The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).	got7fsn_ti	alkene substituted compound metabolic process|alkene substituted compound metabolism	https://github.com/geneontology/go-ontology/issues/19936					krc	2020-09-02T23:13:44Z						biological_process											owl:Class	
GO:0052193	biolink:NamedThing	obsolete movement in symbiont environment	OBSOLETE. The directed movement of an organism or motile cell on, within or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti										True				biological_process											owl:Class	
GO:0086098	biolink:NamedThing	angiotensin-activated signaling pathway involved in heart process	An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.	got7fsn_ti	angiotensin receptor signalling pathway involved in heart process|angiotensin-mediated signaling pathway involved in heart process|angiotensin receptor signaling pathway involved in heart process						bf							biological_process											owl:Class	
GO:0019851	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018329	biolink:NamedThing	obsolete enzyme active site formation via N6-(phospho-5'-adenosine)-L-lysine	OBSOLETE. The transient adenylylation of lysine to form N6-(phospho-5'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:4944632 and and PMID:3882425.	GO:0003910				True		RESID:AA0227		biological_process											owl:Class	
GO:0051831	biolink:NamedThing	obsolete growth or development in other organism during symbiotic interaction	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism.	got7fsn_ti	invasive growth|growth or development within other organism during symbiotic interaction|growth or development in other organism during symbiotic interaction				This term was made obsolete because it contained a conjunction (or).					True				biological_process											owl:Class	
GO:1905845	biolink:NamedThing	positive regulation of cellular response to gamma radiation	Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation.	got7fsn_ti	upregulation of cellular response to gamma radiation|activation of cellular response to gamma ray|positive regulation of cellular response to gamma ray|activation of cellular response to gamma-ray photon|up regulation of cellular response to gamma ray|upregulation of cellular response to gamma ray|up-regulation of cellular response to gamma radiation|up regulation of cellular response to gamma-ray photon|up regulation of cellular response to gamma radiation|activation of cellular response to gamma radiation|up-regulation of cellular response to gamma-ray photon|positive regulation of cellular response to gamma-ray photon|upregulation of cellular response to gamma-ray photon|up-regulation of cellular response to gamma ray						rz	2017-01-19T10:24:57Z						biological_process											owl:Class	
GO:0042967	biolink:NamedThing	obsolete acyl-carrier-protein biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of acyl-carrier protein.	got7fsn_ti	acyl carrier protein biosynthesis|ACP biosynthesis|acyl carrier protein biosynthetic process|ACP biosynthetic process|acyl-carrier-protein synthesis|acyl-carrier-protein biosynthesis|acyl-carrier-protein formation|acyl-carrier-protein anabolism|acyl-carrier protein biosynthesis				The reason for obsoletion is that acyl-carrier-protein is synthesized by the ribosome like any other protein.					True				biological_process											owl:Class	
GO:0019871	biolink:NamedThing	sodium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a sodium channel.	got7fsn_ti											GO:0019868			molecular_function											owl:Class	
GO:1905086	biolink:NamedThing	negative regulation of bioluminescence	Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence.	got7fsn_ti	down regulation of bioluminescence|inhibition of bioluminescence|downregulation of bioluminescence|down-regulation of bioluminescence						rph	2016-03-29T07:51:17Z						biological_process											owl:Class	
GO:1905338	biolink:NamedThing	negative regulation of cohesin unloading	Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading.	got7fsn_ti	down regulation of cohesin unloading|downregulation of cohesin unloading|inhibition of cohesin unloading|down-regulation of cohesin unloading						vw	2016-07-26T16:23:58Z						biological_process											owl:Class	
GO:1901435	biolink:NamedThing	negative regulation of toluene catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process.	got7fsn_ti	down regulation of toluene catabolic process|down regulation of toluene catabolism|negative regulation of toluene degradation|negative regulation of toluene breakdown|downregulation of toluene catabolism|down regulation of toluene breakdown|down-regulation of toluene catabolism|inhibition of toluene degradation|inhibition of toluene catabolic process|down-regulation of toluene breakdown|down-regulation of toluene degradation|inhibition of toluene catabolism|downregulation of toluene catabolic process|down-regulation of toluene catabolic process|downregulation of toluene breakdown|down regulation of toluene degradation|inhibition of toluene breakdown|negative regulation of toluene catabolism|downregulation of toluene degradation						tt	2012-10-01T21:13:41Z						biological_process											owl:Class	
GO:0022884	biolink:NamedThing	macromolecule transmembrane transporter activity	Enables the transfer of a macromolecule from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:0070072	biolink:NamedThing	vacuolar proton-transporting V-type ATPase complex assembly	The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.	got7fsn_ti	V-ATPase complex assembly|V-ATPase assembly													biological_process											owl:Class	
GO:0031661	biolink:NamedThing	obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.	got7fsn_ti	G2/M-specific downregulation of cyclin-dependent protein kinase activity|G2/M-specific inhibition of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity involved in G2/M|G2/M-specific negative regulation of cyclin-dependent protein kinase activity|G2/M-specific down regulation of cyclin-dependent protein kinase activity|G2/M-specific down-regulation of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity during G2/M				This term was obsoleted because it is a MF represented as a BP.	GO:0010389				True				biological_process											owl:Class	
GO:0046092	biolink:NamedThing	deoxycytidine metabolic process	The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.	got7fsn_ti	deoxycytidine metabolism													biological_process											owl:Class	
GO:0016487	biolink:NamedThing	farnesol metabolic process	The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.	got7fsn_ti	farnesol metabolism													biological_process											owl:Class	
GO:0060568	biolink:NamedThing	regulation of peptide hormone processing	Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.	got7fsn_ti							dph	2009-04-29T03:16:05Z						biological_process											owl:Class	
GO:0009568	biolink:NamedThing	amyloplast starch grain	Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.	got7fsn_ti	amyloplast starch granule													cellular_component											owl:Class	
GO:1904028	biolink:NamedThing	positive regulation of collagen fibril organization	Any process that activates or increases the frequency, rate or extent of collagen fibril organization.	got7fsn_ti	up-regulation of fibrillar collagen organization|up regulation of collagen fibril organisation|upregulation of collagen fibril organisation|up-regulation of collagen fibril organization|up regulation of collagen fibril organization|positive regulation of fibrillar collagen organization|up-regulation of collagen fibril organisation|upregulation of collagen fibril organization|upregulation of fibrillar collagen organization|up regulation of fibrillar collagen organization|activation of collagen fibril organization|activation of fibrillar collagen organization|positive regulation of collagen fibril organisation|activation of collagen fibril organisation						ae	2015-03-12T12:37:06Z						biological_process											owl:Class	
GO:0016946	biolink:NamedThing	obsolete cathepsin F activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Cleavage of substrates with Phe and Leu in P2.	got7fsn_ti	cathepsin F activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
UBERON:0006182	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902841	biolink:NamedThing	regulation of netrin-activated signaling pathway	Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway.	got7fsn_ti	regulation of netrin-activated signalling pathway|regulation of netrin-mediated signaling pathway|regulation of netrin-activated signal transduction pathway|regulation of netrin signaling pathway						kmv	2014-04-01T15:24:46Z						biological_process											owl:Class	
GO:0100027	biolink:NamedThing	obsolete regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cell separation after cytokinesis.	got7fsn_ti							cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0060807	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0001714	dph	2009-08-06T02:14:09Z		True				biological_process											owl:Class	
GO:0005095	biolink:NamedThing	GTPase inhibitor activity	Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.	got7fsn_ti	GIP													molecular_function											owl:Class	
GO:0045663	biolink:NamedThing	positive regulation of myoblast differentiation	Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti	activation of myoblast differentiation|up regulation of myoblast differentiation|up-regulation of myoblast differentiation|stimulation of myoblast differentiation|upregulation of myoblast differentiation													biological_process											owl:Class	
GO:0032752	biolink:NamedThing	positive regulation of interleukin-3 production	Any process that activates or increases the frequency, rate, or extent of interleukin-3 production.	got7fsn_ti	positive regulation of interleukin-3 biosynthetic process|stimulation of interleukin-3 production|positive regulation of IL-3 production|activation of interleukin-3 production|upregulation of interleukin-3 production|up-regulation of interleukin-3 production|up regulation of interleukin-3 production										GO:0045401			biological_process											owl:Class	
GO:0033629	biolink:NamedThing	negative regulation of cell adhesion mediated by integrin	Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.	got7fsn_ti	negative regulation of cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:1903823	biolink:NamedThing	telomere single strand break repair	Single strand break repair that takes place in a telomere.	got7fsn_ti	telomere SSBR|telomeric single strand break repair|single strand break repair in telomere|telomere single-strand break repair						jl	2015-01-19T16:12:29Z						biological_process											owl:Class	
GO:1905476	biolink:NamedThing	negative regulation of protein localization to membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.	got7fsn_ti	inhibition of protein localisation in membrane|down regulation of protein localisation in membrane|down regulation of protein localization in membrane|down-regulation of protein localization in membrane|down-regulation of protein localisation in membrane|negative regulation of protein localization in membrane|downregulation of protein localization in membrane|inhibition of protein localization to membrane|downregulation of protein localisation in membrane|inhibition of protein localization in membrane|downregulation of protein localization to membrane|down-regulation of protein localization to membrane|negative regulation of protein localisation in membrane|down regulation of protein localization to membrane						bc	2016-09-21T16:20:10Z						biological_process											owl:Class	
GO:0036116	biolink:NamedThing	long-chain fatty-acyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	long-chain fatty-acyl-CoA degradation|long-chain fatty-acyl-CoA breakdown|long-chain fatty-acyl-CoA catabolism						bf	2012-02-15T11:30:24Z						biological_process											owl:Class	
GO:1901487	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels	OBSOLETE. Positive regulation of transcription factor catabolism in response to increased oxygen levels, which results in negative regulation of the SREBP signaling pathway.	got7fsn_ti	negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation, in response to elevated oxygen|negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling by positive regulation of transcription factor catabolism in response to increased oxygen levels|negative regulation of SREBP signaling by acceleration of SREBP degradation, in response to increased oxygen levels|negative regulation of SREBP-mediated signaling pathway in presence of oxygen by positive regulation of transcription factor catabolic process	https://github.com/geneontology/go-ontology/issues/14544			The reason for obsoletion is that this is better captured in a GO-CAM model.		bf	2012-10-09T08:23:33Z		True				biological_process											owl:Class	
GO:1902222	biolink:NamedThing	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid.	got7fsn_ti	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolism|erythrose 4-phosphate/phosphoenolpyruvate family amino acid degradation|erythrose 4-phosphate/phosphoenolpyruvate family amino acid breakdown						pr	2013-06-13T10:37:43Z						biological_process											owl:Class	
GO:1903279	biolink:NamedThing	regulation of calcium:sodium antiporter activity	Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity.	got7fsn_ti	regulation of sodium/calcium exchanger|regulation of mitochondrial sodium/calcium ion exchange|regulation of sodium:calcium exchange						rl	2014-08-11T12:53:30Z						biological_process											owl:Class	
GO:0005181	biolink:NamedThing	obsolete glycopeptide hormone	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	glycopeptide hormone				This term was made obsolete because it describes a type of hormone rather than a molecular function.	GO:0005179				True				molecular_function											owl:Class	
GO:0005998	biolink:NamedThing	xylulose catabolic process	The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose.	got7fsn_ti	xylulose catabolism|xylulose degradation|xylulose breakdown											MetaCyc:XYLCAT-PWY		biological_process											owl:Class	
GO:1900221	biolink:NamedThing	regulation of amyloid-beta clearance	Any process that modulates the frequency, rate or extent of amyloid-beta clearance.	got7fsn_ti	regulation of beta-amyloid clearance						vk	2012-03-22T01:29:32Z						biological_process											owl:Class	
GO:0006889	biolink:NamedThing	obsolete regulation of calcium in ER	OBSOLETE. Any process that modulates the concentration of calcium in the endoplasmic reticulum.	got7fsn_ti	regulation of calcium in ER				This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport').	GO:0006874|GO:0005783				True				biological_process											owl:Class	
GO:0008472	biolink:NamedThing	obsolete metallocarboxypeptidase D activity	OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid.	got7fsn_ti	gp180 (duck)|carboxypeptidase D (cattle, human, mouse, rat)|metallocarboxypeptidase D activity			GO:0004181	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0030364	biolink:NamedThing	obsolete cleavage and polyadenylylation specificity factor activity	OBSOLETE. A factor required in mRNA 3' end processing for both the cleavage and poly(A) addition reactions and, consistent with this function, recognizes AAUAAA, a signal also essential for both reactions.	got7fsn_ti	cleavage and polyadenylation specificity factor activity|CPSF|cleavage/polyadenylation specificity factor activity|cleavage and polyadenylylation specificity factor activity			GO:0005847	This term was made obsolete because it describes a cellular component.	GO:0006378|GO:0006379				True				molecular_function											owl:Class	
GO:2000834	biolink:NamedThing	regulation of androgen secretion	Any process that modulates the frequency, rate or extent of androgen secretion.	got7fsn_ti							bf	2011-07-26T08:39:45Z						biological_process											owl:Class	
GO:0106253	biolink:NamedThing	positive regulation of DNA strand resection involved in replication fork processing	Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing.	got7fsn_ti							hjd	2020-02-24T15:31:30Z						biological_process											owl:Class	
GO:0002612	biolink:NamedThing	positive regulation of plasmacytoid dendritic cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.	got7fsn_ti	stimulation of plasmacytoid dendritic cell antigen processing and presentation|upregulation of plasmacytoid dendritic cell antigen processing and presentation|activation of plasmacytoid dendritic cell antigen processing and presentation|up regulation of plasmacytoid dendritic cell antigen processing and presentation|up-regulation of plasmacytoid dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0061091	biolink:NamedThing	regulation of phospholipid translocation	Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	got7fsn_ti							dph	2010-04-26T01:54:22Z						biological_process											owl:Class	
GO:0070104	biolink:NamedThing	negative regulation of interleukin-6-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.	got7fsn_ti	negative regulation of IL-6-mediated signaling pathway|negative regulation of interleukin-6-mediated signalling pathway													biological_process											owl:Class	
GO:0070952	biolink:NamedThing	regulation of neutrophil mediated killing of gram-positive bacterium	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.	got7fsn_ti							mah	2009-10-01T02:14:36Z						biological_process											owl:Class	
UBERON:0004133	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009005	biolink:NamedThing	obsolete signal peptidase II activity	OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from membrane prolipoproteins. Hydrolyzes the terminal bond of Xaa-Xbb-Xbb-Cys, in which Xaa is hydrophobic (preferably Leu), Xbb is often Ser or Ala, Xcc is often Gly or Ala, and the Cys is alkylated on sulfur with a diacylglyceryl group.	got7fsn_ti	signal peptidase II activity|premurein-leader peptidase activity|premurein leader proteinase activity|SPase II activity|prolipoprotein-signal peptidase activity|prolipoprotein signal peptidase activity|lipoprotein signal peptidase activity|leader peptidase II			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0051843	biolink:NamedThing	obsolete evasion or tolerance of symbiont defense response	OBSOLETE. Any process, either active or passive, by which an organism avoids or tolerates the effects of a symbiont organism's defense response. The symbiont defense response is mounted by the symbiont in response to the presence of the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	evasion or tolerance of symbiont defense response|evasion of symbiont defence response				This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
GO:1900169	biolink:NamedThing	regulation of glucocorticoid mediated signaling pathway	Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway.	got7fsn_ti	regulation of glucocorticoid mediated signalling						hjd	2012-03-08T08:33:16Z						biological_process											owl:Class	
GO:0060666	biolink:NamedThing	dichotomous subdivision of terminal units involved in salivary gland branching	The process in which a salivary epithelial cord bifurcates at its end.	got7fsn_ti							dph	2009-06-01T09:38:40Z						biological_process											owl:Class	
GO:0090012	biolink:NamedThing	negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation	Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak.	got7fsn_ti	negative regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation						tb	2009-07-29T10:51:57Z						biological_process											owl:Class	
GO:0001972	biolink:NamedThing	retinoic acid binding	Binding to retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0030161	biolink:NamedThing	obsolete calpain inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue.	got7fsn_ti	calpain inhibitor activity			GO:0010859	This term was made obsolete because it represents a regulator of a non-existent molecular function.					True				molecular_function											owl:Class	
CHEBI:18250	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900468	biolink:NamedThing	regulation of phosphatidylserine biosynthetic process	Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process.	got7fsn_ti	regulation of phosphatidylserine formation|regulation of phosphatidylserine synthesis|regulation of phosphatidylserine biosynthesis|regulation of phosphatidylserine anabolism						dgf	2012-05-01T08:01:01Z						biological_process											owl:Class	
GO:0072415	biolink:NamedThing	obsolete detection of stimulus involved in spindle checkpoint	OBSOLETE. The series of events in which information about the assembly, orientation or integrity of the spindle is received and converted into a molecular signal, contributing to a spindle checkpoint.	got7fsn_ti	spindle checkpoint sensor process|sensing involved in spindle checkpoint|spindle checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:54:50Z		True				biological_process											owl:Class	
GO:1990694	biolink:NamedThing	intrinsic component of Golgi medial cisterna membrane	The component of the Golgi medial cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic component of medial-Golgi cisterna membrane						bhm	2015-03-12T10:29:12Z						cellular_component											owl:Class	
GO:1900996	biolink:NamedThing	benzene catabolic process	The chemical reactions and pathways resulting in the breakdown of benzene.	got7fsn_ti	benzene degradation|benzene breakdown|benzene catabolism						yaf	2012-06-14T02:53:38Z						biological_process											owl:Class	
GO:2000922	biolink:NamedThing	negative regulation of arabinoxylan-containing compound catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process.	got7fsn_ti	negative regulation of arabinoxylan catabolism						tt	2011-08-01T12:39:00Z						biological_process											owl:Class	
GO:0090370	biolink:NamedThing	negative regulation of cholesterol efflux	Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.	got7fsn_ti							tb	2010-07-12T11:26:04Z						biological_process											owl:Class	
GO:0060549	biolink:NamedThing	regulation of fructose 1,6-bisphosphate 1-phosphatase activity	Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.	got7fsn_ti							dph	2009-04-13T02:07:32Z						biological_process											owl:Class	
GO:2000400	biolink:NamedThing	positive regulation of thymocyte aggregation	Any process that activates or increases the frequency, rate or extent of thymocyte aggregation.	got7fsn_ti	positive regulation of immature T-lymphocyte aggregation|positive regulation of immature T cell aggregation|positive regulation of immature T-cell aggregation|positive regulation of T cell precursor aggregation|positive regulation of thymic lymphocyte aggregation						mah	2011-02-22T02:50:01Z						biological_process											owl:Class	
CHEBI:25166	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042336	biolink:NamedThing	obsolete cuticle development involved in protein-based cuticle molting cycle	OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. Examples of this process are found in invertebrate species.	got7fsn_ti	cuticle anabolism during molting|cuticle biosynthetic process during molting|cuticle formation during molting|cuticle synthesis during molting|cuticle development involved in protein-based cuticle molting cycle				This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0042337|GO:0042338				True				biological_process											owl:Class	
GO:0033626	biolink:NamedThing	positive regulation of integrin activation by cell surface receptor linked signal transduction	Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands.	got7fsn_ti	cell surface receptor linked signal transduction leading to integrin complex activation|cell surface receptor linked signal transduction leading to integrin activation													biological_process											owl:Class	
GO:1903908	biolink:NamedThing	positive regulation of plasma membrane raft polarization	Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization.	got7fsn_ti	upregulation of plasma membrane raft polarization|activation of plasma membrane raft polarization|up-regulation of plasma membrane raft polarization|up regulation of plasma membrane raft polarization						als	2015-02-09T10:54:15Z						biological_process											owl:Class	
GO:0016356	biolink:NamedThing	obsolete organophosphorus susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	organophosphorus susceptibility/resistance			GO:0046683	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0035603	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in hemopoiesis	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.	got7fsn_ti	FGFR signaling pathway involved in hematopoiesis|fibroblast growth factor receptor signaling pathway involved in hematopoiesis|FGF receptor signaling pathway involved in hematopoiesis|fibroblast growth factor receptor signalling pathway involved in hemopoiesis						bf	2010-11-15T11:09:46Z						biological_process											owl:Class	
GO:1902972	biolink:NamedThing	premeiotic DNA replication DNA ligation	Any DNA ligation involved in meiotic cell cycle DNA replication.	got7fsn_ti	DNA ligation involved in meiotic DNA replication|DNA ligation involved in meiotic cell cycle DNA replication						jl	2014-05-06T15:20:53Z						biological_process											owl:Class	
GO:0019700	biolink:NamedThing	organic phosphonate catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.	got7fsn_ti	phosphonate degradation|organophosphonate catabolic process|phosphonate catabolism|phosphonate breakdown													biological_process											owl:Class	
GO:1990842	biolink:NamedThing	obsolete response to prenatal stress	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis in the embryo or fetus during pregnancy.	got7fsn_ti	response to PNS				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-08-31T15:15:29Z		True				biological_process											owl:Class	
GO:1902634	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	got7fsn_ti	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation				Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name.		di	2014-01-18T00:34:36Z						biological_process											owl:Class	
GO:1904353	biolink:NamedThing	regulation of telomere capping	Any process that modulates the frequency, rate or extent of telomere capping.	got7fsn_ti	regulation of telomere end protection						nc	2015-06-12T16:51:08Z						biological_process											owl:Class	
GO:1902374	biolink:NamedThing	regulation of rRNA catabolic process	Any process that modulates the frequency, rate or extent of rRNA catabolic process.	got7fsn_ti	regulation of rRNA catabolism|regulation of rRNA breakdown|regulation of rRNA degradation						bf	2013-08-22T15:20:59Z						biological_process											owl:Class	
GO:1905434	biolink:NamedThing	positive regulation of retrograde trans-synaptic signaling by neuropeptide	Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.	got7fsn_ti	positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling|activation of retrograde trans-synaptic signaling by neuropeptide|up-regulation of retrograde trans-synaptic signaling by neuropeptide|upregulation of retrograde trans-synaptic signaling by neuropeptide|up regulation of retrograde trans-synaptic signaling by neuropeptide						bf	2016-09-14T10:57:02Z						biological_process											owl:Class	
GO:0008423	biolink:NamedThing	obsolete bleomycin hydrolase activity	OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.	got7fsn_ti	aminopeptidase C (Lactococcus lactis)|bleomycin hydrolase activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0007570	biolink:NamedThing	obsolete age dependent accumulation of genetic damage	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	age dependent accumulation of genetic damage				This term was made obsolete because it does not describe a biological process.	GO:0001301				True				biological_process											owl:Class	
GO:1904163	biolink:NamedThing	obsolete regulation of triglyceride homeostasis	OBSOLETE. Any process that modulates the frequency, rate or extent of triglyceride homeostasis.	got7fsn_ti	regulation of triacylglycerol homeostasis				This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2015-04-22T11:04:43Z		True				biological_process											owl:Class	
GO:1905405	biolink:NamedThing	regulation of mitotic cohesin loading	Any process that modulates the frequency, rate or extent of mitotic cohesin loading.	got7fsn_ti							vw	2016-08-25T14:48:46Z						biological_process											owl:Class	
GO:2000668	biolink:NamedThing	regulation of dendritic cell apoptotic process	Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process.	got7fsn_ti	regulation of dendritic cell apoptosis						pr	2011-05-09T07:34:16Z						biological_process											owl:Class	
GO:0033392	biolink:NamedThing	obsolete actin homodimerization activity	OBSOLETE. Binding to an identical actin monomer to form a homodimer.	got7fsn_ti	actin polymerizing activity|actin homodimerization activity|actin dimerization activity				This term was made obsolete because it was added in error; formation of an actin dimer is simply a transient step in the polymerization of actin. Also, this term may not represent a real molecular function in GO, but rather that a gene product (actin itself) is part of an actin homodimer transient protein complex.					True				molecular_function											owl:Class	
GO:2001304	biolink:NamedThing	lipoxin B4 metabolic process	The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.	got7fsn_ti	lipoxin B4 metabolism|LXB4 metabolism|LXB4 metabolic process						bf	2012-03-07T11:14:58Z						biological_process											owl:Class	
GO:1902985	biolink:NamedThing	mitotic pre-replicative complex assembly	Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication.	got7fsn_ti	nuclear pre-replicative complex assembly involved in mitotic cell cycle|pre-replicative complex assembly involved in mitotic cell cycle DNA replication						jl	2014-05-06T20:33:34Z						biological_process											owl:Class	
GO:2000854	biolink:NamedThing	positive regulation of corticosterone secretion	Any process that activates or increases the frequency, rate or extent of corticosterone secretion.	got7fsn_ti							bf	2011-07-26T08:45:45Z						biological_process											owl:Class	
GO:0035227	biolink:NamedThing	regulation of glutamate-cysteine ligase activity	Any process that modulates the activity of glutamate-cysteine ligase.	got7fsn_ti														biological_process											owl:Class	
GO:1903404	biolink:NamedThing	positive regulation of renal phosphate excretion	Any process that activates or increases the frequency, rate or extent of renal phosphate excretion.	got7fsn_ti	positive regulation of renal phosphate ion excretion|activation of renal phosphate ion excretion|activation of renal phosphate excretion|up regulation of renal phosphate ion excretion|up regulation of renal phosphate excretion|upregulation of renal phosphate ion excretion|up-regulation of renal phosphate ion excretion|up-regulation of renal phosphate excretion|upregulation of renal phosphate excretion						pm	2014-09-01T13:47:18Z						biological_process											owl:Class	
GO:0100070	biolink:NamedThing	obsolete obsolete regulation of fatty acid biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fatty acid biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0046443	biolink:NamedThing	FAD metabolic process	The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide.	got7fsn_ti	oxidized flavin adenine dinucleotide metabolism|oxidized flavin adenine dinucleotide metabolic process|FAD metabolism|oxidized flavin-adenine dinucleotide metabolic process|oxidized flavin-adenine dinucleotide metabolism													biological_process											owl:Class	
GO:0009203	biolink:NamedThing	ribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	ribonucleoside triphosphate breakdown|ribonucleoside triphosphate degradation|ribonucleoside triphosphate catabolism													biological_process											owl:Class	
GO:0008581	biolink:NamedThing	obsolete ubiquitin-specific protease 5 activity	OBSOLETE. Catalysis of the hydrolysis of the Gly76-Lys48 isopeptide bond of polyubiquitin.	got7fsn_ti	ubiquitin isopeptidase T activity|ubiquitin-specific protease 5 activity			GO:0004843	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0030657	biolink:NamedThing	obsolete regulation of coenzyme and prosthetic group metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups.	got7fsn_ti	regulation of coenzyme and prosthetic group metabolic process				This term was made obsolete because it was replaced by more specific terms.	GO:0051199				True				biological_process											owl:Class	
GO:0046282	biolink:NamedThing	cinnamic acid ester catabolic process	The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid.	got7fsn_ti	cinnamic acid ester catabolism|cinnamic acid ester breakdown|cinnamic acid ester degradation													biological_process											owl:Class	
GO:1902607	biolink:NamedThing	negative regulation of large conductance calcium-activated potassium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity.	got7fsn_ti	downregulation of large conductance calcium-activated potassium channel activity|down-regulation of large conductance KCa channels|inhibition of BK calcium-activated potassium channel activity|negative regulation of BK KCa channels|inhibition of large conductance KCa channels|negative regulation of large conductance KCa channels|inhibition of BK KCa channels|down-regulation of BK channel activity|down-regulation of large conductance calcium-activated potassium channel activity|down regulation of BK KCa channels|downregulation of BK channel activity|down regulation of BK calcium-activated potassium channel activity|downregulation of large conductance KCa channels|inhibition of BK channel activity|negative regulation of BK calcium-activated potassium channel activity|down-regulation of BK KCa channels|inhibition of large conductance calcium-activated potassium channel activity|downregulation of BK calcium-activated potassium channel activity|down regulation of large conductance calcium-activated potassium channel activity|down regulation of large conductance KCa channels|down regulation of BK channel activity|downregulation of BK KCa channels|negative regulation of BK channel activity|down-regulation of BK calcium-activated potassium channel activity						sl	2014-01-02T18:51:12Z						biological_process											owl:Class	
GO:0060815	biolink:NamedThing	regulation of translation involved in anterior/posterior axis specification	Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis.	got7fsn_ti							dph	2009-08-07T10:02:31Z						biological_process											owl:Class	
GO:0042990	biolink:NamedThing	obsolete regulation of transcription factor import into nucleus	OBSOLETE. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.	got7fsn_ti	regulation of transcription factor transport from cytoplasm to nucleus|regulation of transcription factor import into cell nucleus|regulation of transcription factor-nucleus import				The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0042306				True				biological_process											owl:Class	
GO:0014049	biolink:NamedThing	positive regulation of glutamate secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.	got7fsn_ti	activation of glutamate secretion|upregulation of glutamate secretion|up-regulation of glutamate secretion|up regulation of glutamate secretion|stimulation of glutamate secretion													biological_process											owl:Class	
GO:0061672	biolink:NamedThing	glutathione hydrolase complex	Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly.	got7fsn_ti	glutamine amidotransferase II complex|glutathionase complex|gamma-glutamyltranspeptidase complex						dph	2014-11-24T14:38:08Z						cellular_component											owl:Class	
GO:0106129	biolink:NamedThing	positive regulation of store-operated calcium entry	Any process that activates or increases the frequency, rate or extent of store-operated calcium entry.	got7fsn_ti							hjd	2018-05-10T19:02:40Z						biological_process											owl:Class	
CHEBI:64405	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015524	biolink:NamedThing	obsolete L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity	OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out).	got7fsn_ti	L-arabinose/beta-D-thiogalactopyranoside:proton antiporter activity|L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity				This term was made obsolete because it represents a gene product rather than a single discrete molecular function.	GO:0051119|GO:0015147|GO:0015299				True				molecular_function											owl:Class	
GO:2001058	biolink:NamedThing	D-tagatose 6-phosphate metabolic process	The chemical reactions and pathways involving a D-tagatose 6-phosphate.	got7fsn_ti	D-tagatose 6-phosphate metabolism						jl	2011-09-09T03:21:28Z						biological_process											owl:Class	
GO:0015810	biolink:NamedThing	aspartate transmembrane transport	The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	mitochondrial aspartate/glutamate transport|aspartate transport													biological_process											owl:Class	
GO:0051095	biolink:NamedThing	regulation of helicase activity	Any process that modulates the frequency, rate or extent of helicase activity.	got7fsn_ti														biological_process											owl:Class	
GO:0010924	biolink:NamedThing	regulation of inositol-polyphosphate 5-phosphatase activity	Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:1905013	biolink:NamedThing	negative regulation of 'de novo' NAD biosynthetic process from tryptophan	Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.	got7fsn_ti	downregulation of de novo NAD biosynthetic process from tryptophan|down-regulation of 'de novo' NAD biosynthetic process from tryptophan|downregulation of 'de novo' NAD biosynthetic process from tryptophan|negative regulation of de novo NAD biosynthetic process from tryptophan|inhibition of de novo NAD biosynthetic process from tryptophan|down regulation of de novo NAD biosynthetic process from tryptophan|inhibition of 'de novo' NAD biosynthetic process from tryptophan|down regulation of 'de novo' NAD biosynthetic process from tryptophan|down-regulation of de novo NAD biosynthetic process from tryptophan						bf	2016-03-03T10:01:00Z						biological_process											owl:Class	
GO:0005367	biolink:NamedThing	myo-inositol:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in).	got7fsn_ti	myo-inositol-sodium cotransporter activity											Reactome:R-HSA-429663		molecular_function											owl:Class	
GO:1905341	biolink:NamedThing	negative regulation of protein localization to kinetochore	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore.	got7fsn_ti	downregulation of condensin localization to kinetochore|down regulation of protein localization to kinetochore|inhibition of condensin localization to kinetochore|inhibition of protein localization to kinetochore|down-regulation of condensin localization to kinetochore|inhibition of protein localisation to kinetochore|negative regulation of condensin localization to kinetochore|downregulation of protein localization to kinetochore|downregulation of protein localisation to kinetochore|negative regulation of protein localisation to kinetochore|down-regulation of protein localisation to kinetochore|down-regulation of protein localization to kinetochore|down regulation of protein localisation to kinetochore|down regulation of condensin localization to kinetochore				Q9H211 in Human in PMID:22581055		es	2016-07-27T15:26:44Z						biological_process											owl:Class	
GO:0106187	biolink:NamedThing	obsolete translocase activity acting on hydrons linked to oxidoreductase reactions	OBSOLETE. Catalysis of the translocation of hydrons linked to an oxidoreduction reaction.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-07T18:04:40Z		True		EC:7.1.1.-		molecular_function											owl:Class	
GO:2001169	biolink:NamedThing	regulation of ATP biosynthetic process	Any process that modulates the frequency, rate or extent of ATP biosynthetic process.	got7fsn_ti	regulation of ATP regeneration|regulation of ATP anabolism|regulation of ATP biosynthesis|regulation of ATP synthesis|regulation of ATP formation						kmv	2011-10-26T03:18:03Z						biological_process											owl:Class	
GO:2000929	biolink:NamedThing	positive regulation of cellodextrin catabolic process	Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process.	got7fsn_ti	positive regulation of cellodextrin catabolism						tt	2011-08-01T12:41:36Z						biological_process											owl:Class	
GO:0150073	biolink:NamedThing	regulation of protein-glutamine gamma-glutamyltransferase activity	Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.	got7fsn_ti							bc	2018-07-25T10:03:10Z						biological_process											owl:Class	
GO:0009919	biolink:NamedThing	obsolete cytokinesis (sensu Viridiplantae)	OBSOLETE. The division of a cell into two daughter cells with cell walls.	got7fsn_ti	cytokinesis (sensu Viridiplantae)				This term was made obsolete because its meaning was changed significantly.	GO:0000911				True				biological_process											owl:Class	
GO:1903660	biolink:NamedThing	negative regulation of complement-dependent cytotoxicity	Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.	got7fsn_ti	downregulation of complement-dependent cytotoxicity|down regulation of complement-dependent cytotoxicity|down-regulation of complement-dependent cytotoxicity|inhibition of complement-dependent cytotoxicity						jl	2014-11-25T15:04:02Z						biological_process											owl:Class	
GO:0003822	biolink:NamedThing	obsolete MHC-interacting protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	MHC-interacting protein				This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0044451	biolink:NamedThing	obsolete nucleoplasm part	OBSOLETE. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005654				True				cellular_component											owl:Class	
GO:1900845	biolink:NamedThing	positive regulation of monodictyphenone biosynthetic process	Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process.	got7fsn_ti	upregulation of monodictyphenone biosynthetic process						di	2012-06-07T09:41:08Z						biological_process											owl:Class	
GO:0061426	biolink:NamedThing	positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of sulfite transport.	got7fsn_ti							dph	2012-02-02T01:21:46Z						biological_process											owl:Class	
GO:0046468	biolink:NamedThing	phosphatidyl-N-monomethylethanolamine metabolic process	The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria.	got7fsn_ti	phosphatidyl-N-monomethylethanolamine metabolism|PMME metabolism|PMME metabolic process													biological_process											owl:Class	
GO:0002616	biolink:NamedThing	regulation of macrophage antigen processing and presentation	Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:0085021	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type I secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type I secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:20:44Z		True				biological_process											owl:Class	
GO:0039583	biolink:NamedThing	obsolete suppression by virus of host PKR activity by positive regulation of PKR catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the degradation of PKR via the proteosome. For example, the Rift Valley fever virus (RVFV) NSs protein induces the down-regulation of PKR by degradation through proteasomes.	got7fsn_ti	promotion by virus of proteosome-dependent PKR degradation|downregulation of PKR by degradation through proteosome				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-05-02T02:49:30Z		True				biological_process											owl:Class	
GO:0002584	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide antigen	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.	got7fsn_ti	inhibition of antigen processing and presentation of peptide antigen|down regulation of antigen processing and presentation of peptide antigen|negative regulation of peptide antigen processing and presentation|down-regulation of antigen processing and presentation of peptide antigen|downregulation of antigen processing and presentation of peptide antigen													biological_process											owl:Class	
GO:1990940	biolink:NamedThing	obsolete microtubule sliding involved in mitotic spindle elongation	OBSOLETE. The movement of one microtubule along another microtubule involved in mitotic spindle elongation.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2016-04-04T11:06:41Z		True				biological_process											owl:Class	
GO:1902241	biolink:NamedThing	copal-8-ol diphosphate(3-) metabolic process	The chemical reactions and pathways involving copal-8-ol diphosphate(3-).	got7fsn_ti	copal-8-ol diphosphate(3-) metabolism						ms	2013-06-20T09:09:27Z						biological_process											owl:Class	
GO:0120271	biolink:NamedThing	negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18757					krc	2020-10-08T21:01:06Z						biological_process											owl:Class	
GO:0033568	biolink:NamedThing	lactoferrin receptor activity	Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.	got7fsn_ti														molecular_function											owl:Class	
GO:0010957	biolink:NamedThing	negative regulation of vitamin D biosynthetic process	Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	got7fsn_ti							tb	2009-05-06T11:25:12Z						biological_process											owl:Class	
GO:0039531	biolink:NamedThing	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm.	got7fsn_ti	regulation of MAV signaling|regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway						bf	2012-01-03T11:06:56Z						biological_process											owl:Class	
GO:1901846	biolink:NamedThing	positive regulation of cell communication by electrical coupling involved in cardiac conduction	Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.	got7fsn_ti	upregulation of cell communication by electrical coupling involved in cardiac conduction|up-regulation of cell communication by electrical coupling involved in cardiac conduction|activation of cell communication by electrical coupling involved in cardiac conduction|up regulation of cell communication by electrical coupling involved in cardiac conduction						rl	2013-01-24T19:15:49Z						biological_process											owl:Class	
GO:0043397	biolink:NamedThing	regulation of corticotropin-releasing hormone secretion	Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion.	got7fsn_ti	regulation of CRH secretion|regulation of corticotropin-releasing factor secretion|regulation of CRF secretion													biological_process											owl:Class	
GO:0140420	biolink:NamedThing	heme import into cell	The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.	got7fsn_ti	heme assimilation	https://github.com/geneontology/go-ontology/issues/18671					pg	2020-01-30T13:10:07Z						biological_process											owl:Class	
GO:1901800	biolink:NamedThing	positive regulation of proteasomal protein catabolic process	Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.	got7fsn_ti	upregulation of proteasome-mediated protein catabolic process|up-regulation of proteasome-mediated protein catabolism|upregulation of proteasomal protein catabolic process|up regulation of proteasome-mediated protein catabolism|activation of proteasomal protein catabolic process|up-regulation of proteasome-mediated protein catabolic process|upregulation of proteasome-mediated protein catabolism|up regulation of proteasome-mediated protein catabolic process|activation of proteasome-mediated protein catabolism|positive regulation of proteasome-mediated protein catabolism|up-regulation of proteasomal protein catabolic process|positive regulation of proteasome-mediated protein catabolic process|up regulation of proteasomal protein catabolic process|activation of proteasome-mediated protein catabolic process						rl	2013-01-21T20:10:58Z						biological_process											owl:Class	
UBERON:0005136	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031342	biolink:NamedThing	negative regulation of cell killing	Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.	got7fsn_ti	down-regulation of cell killing|inhibition of cell killing|downregulation of cell killing|down regulation of cell killing													biological_process											owl:Class	
GO:0001633	biolink:NamedThing	obsolete secretin-like receptor activity	OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the secretin receptor.	got7fsn_ti	secretin-like receptor activity|class B G-protein coupled receptor|class B orphan receptor activity|class B GPCR|class B G protein coupled receptor				This term was made obsolete because it represents a gene product and is named based on protein features.					True	GO:0001638			molecular_function											owl:Class	
GO:0007336	biolink:NamedThing	obsolete bilateral process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	bilateral process				This term was made obsolete because it gives no indication of what it refers to.					True				biological_process											owl:Class	
GO:0044129	biolink:NamedThing	positive regulation of development of symbiont in host	Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti					This term partially replaces the obsolete term 'positive regulation of growth or development of symbiont in host ; GO:0033666'. See also 'positive regulation of growth of symbiont in host ; GO:0044128'.		jl	2009-08-04T02:25:41Z						biological_process											owl:Class	
GO:1904070	biolink:NamedThing	ascaroside biosynthetic process	The chemical reactions and pathways resulting in the formation of ascaroside.	got7fsn_ti	ascaroside synthesis|ascaroside anabolism|ascaroside formation|ascaroside biosynthesis						kmv	2015-03-20T02:40:20Z						biological_process											owl:Class	
GO:0110042	biolink:NamedThing	negative regulation of pharynx morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis.	got7fsn_ti							kmv	2017-07-24T21:05:08Z						biological_process											owl:Class	
GO:0003080	biolink:NamedThing	obsolete negative regulation of natriuresis	OBSOLETE. Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.	got7fsn_ti	negative regulation of natriuresis				This term was made obsolete because its definition was inaccurate.	GO:0035814				True				biological_process											owl:Class	
GO:0075232	biolink:NamedThing	obsolete positive regulation of spore movement on or near host	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:0031308	biolink:NamedThing	intrinsic component of nuclear outer membrane	The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to nuclear outer membrane													cellular_component											owl:Class	
GO:0006026	biolink:NamedThing	aminoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.	got7fsn_ti	aminoglycan degradation|aminoglycan catabolism|aminoglycan breakdown													biological_process											owl:Class	
GO:2000317	biolink:NamedThing	negative regulation of T-helper 17 type immune response	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response.	got7fsn_ti	negative regulation of Th17 immune response						mah	2011-01-18T01:33:00Z						biological_process											owl:Class	
GO:0001573	biolink:NamedThing	ganglioside metabolic process	The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.	got7fsn_ti	ganglioside metabolism													biological_process											owl:Class	
GO:0052211	biolink:NamedThing	obsolete interaction with other organism via protein secreted by type II secretion system involved in symbiotic interaction	OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type II secretion system, where the two organisms are in a symbiotic interaction.	got7fsn_ti	interaction with other organism via protein secreted by type II secretion system during symbiotic interaction				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0009191	biolink:NamedThing	ribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	ribonucleoside diphosphate degradation|ribonucleoside diphosphate catabolism|ribonucleoside diphosphate breakdown													biological_process											owl:Class	
GO:0004212	biolink:NamedThing	obsolete lysosomal cysteine-type endopeptidase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lysosomal cysteine-type endopeptidase				This term was made obsolete because it contains both component and function information.	GO:0005764|GO:0004197				True				molecular_function											owl:Class	
CHEBI:26124	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000322	biolink:NamedThing	regulation of glucocorticoid receptor signaling pathway	Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway.	got7fsn_ti	regulation of glucocorticoid receptor signalling pathway						vk	2011-01-18T04:38:10Z						biological_process											owl:Class	
GO:0010250	biolink:NamedThing	S-methylmethionine biosynthetic process	The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.	got7fsn_ti	S-methylmethionine formation|S-methylmethionine synthesis|S-methylmethionine biosynthesis|S-methylmethionine anabolism													biological_process											owl:Class	
GO:1901907	biolink:NamedThing	diadenosine pentaphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate.	got7fsn_ti	diadenosine pentaphosphate catabolism|diadenosyl pentaphosphate catabolic process|diadenosyl pentaphosphate breakdown|diadenosyl pentaphosphate degradation|diadenosyl pentaphosphate catabolism						al	2013-02-13T13:48:21Z						biological_process											owl:Class	
GO:1902529	biolink:NamedThing	negative regulation of protein linear polyubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination.	got7fsn_ti	downregulation of protein linear polyubiquitination|down-regulation of M1 linkage|downregulation of M1 linkage|inhibition of M1 linkage|down-regulation of protein linear polyubiquitination|down regulation of M1 linkage|negative regulation of M1 linkage|down regulation of protein linear polyubiquitination|inhibition of protein linear polyubiquitination						ppm	2013-12-02T10:03:09Z						biological_process											owl:Class	
GO:0045749	biolink:NamedThing	obsolete negative regulation of S phase of mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of S phase of mitotic cell cycle activity.	got7fsn_ti	inhibition of S phase of mitotic cell cycle|down regulation of S phase of mitotic cell cycle|negative regulation of S-phase of mitotic cell cycle|downregulation of S phase of mitotic cell cycle|negative regulation of S phase of mitotic cell cycle|down-regulation of S phase of mitotic cell cycle				This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.					True				biological_process											owl:Class	
GO:0010606	biolink:NamedThing	positive regulation of cytoplasmic mRNA processing body assembly	Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.	got7fsn_ti														biological_process											owl:Class	
GO:0071419	biolink:NamedThing	cellular response to amphetamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.	got7fsn_ti							mah	2009-12-14T04:09:02Z						biological_process											owl:Class	
GO:1902753	biolink:NamedThing	negative regulation of renal amino acid absorption	Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption.	got7fsn_ti	downregulation of renal amino acid absorption|inhibition of renal amino acid absorption|down regulation of renal amino acid absorption|down-regulation of renal amino acid absorption						hjd	2014-03-05T15:44:01Z						biological_process											owl:Class	
GO:1905467	biolink:NamedThing	positive regulation of G-quadruplex DNA unwinding	Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding.	got7fsn_ti	activation of G-quadruplex DNA unwinding|up regulation of G-quadruplex DNA unwinding|up-regulation of G-quadruplex DNA unwinding|upregulation of G-quadruplex DNA unwinding						ans	2016-09-19T12:16:01Z						biological_process											owl:Class	
GO:0033480	biolink:NamedThing	UDP-D-galacturonate biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-D-galacturonate anabolism|UDP-D-galacturonate formation|UDP-D-galacturonate biosynthesis|UDP-D-galacturonate synthesis											MetaCyc:PWY-4		biological_process											owl:Class	
GO:2000064	biolink:NamedThing	regulation of cortisol biosynthetic process	Any process that modulates the frequency, rate or extent of cortisol biosynthetic process.	got7fsn_ti	regulation of cortisol anabolism|regulation of cortisol synthesis|regulation of cortisol biosynthesis|regulation of cortisol formation						jl	2010-08-20T01:51:15Z						biological_process											owl:Class	
GO:0046200	biolink:NamedThing	obsolete m-cresol biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of m-cresol (3-hydroxytoluene), the meta-isoform of cresol.	got7fsn_ti	m-cresol synthesis|m-cresol biosynthetic process|m-cresol anabolism|m-cresol formation|m-cresol biosynthesis			GO:0018925	This term was made obsolete because m-cresol is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1901908	biolink:NamedThing	diadenosine hexaphosphate metabolic process	The chemical reactions and pathways involving diadenosine hexaphosphate.	got7fsn_ti	diadenosyl hexaphosphate metabolic process|diadenosyl hexaphosphate metabolism|diadenosine hexaphosphate metabolism						al	2013-02-13T13:50:40Z						biological_process											owl:Class	
GO:2001078	biolink:NamedThing	(1->6)-beta-D-glucan binding	Binding to (1->6)-beta-D-glucan.	got7fsn_ti	beta-1->6-D-glucan binding|1,6-beta-D-glucan binding|beta-(1->6)-D-glucan binding|(1,6)-beta-D-glucan binding|1->6-beta-D-glucan binding|beta-1,6-D-glucan binding|beta-(1,6)-D-glucan binding						jl	2011-09-15T01:12:50Z						molecular_function											owl:Class	
GO:0016870	biolink:NamedThing	obsolete intramolecular transferase activity, transferring other groups	OBSOLETE. A grouping term for intramolecular transferases that cannot be more accurately categorized.	got7fsn_ti	intramolecular transferase activity, transferring other groups				This term was made obsolete because it was an unnecessary grouping term.	GO:0016866				True				molecular_function											owl:Class	
GO:0003257	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.	got7fsn_ti							dph	2009-10-15T01:07:25Z						biological_process											owl:Class	
GO:0043929	biolink:NamedThing	primary ovarian follicle growth involved in double layer follicle stage	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis.	got7fsn_ti	primary ovarian follicle growth during double layer follicle stage													biological_process											owl:Class	
GO:0008002	biolink:NamedThing	obsolete lamina lucida	OBSOLETE. The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina.	got7fsn_ti					This term was made obsolete because it is thought to be an experimental artefact.					True		Wikipedia:Lamina_lucida		cellular_component											owl:Class	
GO:1904863	biolink:NamedThing	regulation of beta-catenin-TCF complex assembly	Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly.	got7fsn_ti	regulation of beta-catenin/T-cell factor complex formation|regulation of beta-catenin-TCF complex formation|regulation of beta-catenin/LEF complex formation|regulation of beta-catenin/lymphoid enhancer binding factor complex formation|regulation of beta-catenin/LEF complex assembly|regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|regulation of beta-catenin/T-cell factor complex assembly						bf	2015-12-17T13:50:39Z						biological_process											owl:Class	
GO:0042433	biolink:NamedThing	indole catabolic process	The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).	got7fsn_ti	indole breakdown|indole catabolism|indole degradation													biological_process											owl:Class	
GO:1903403	biolink:NamedThing	negative regulation of renal phosphate excretion	Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion.	got7fsn_ti	down regulation of renal phosphate ion excretion|downregulation of renal phosphate excretion|down regulation of renal phosphate excretion|inhibition of renal phosphate excretion|down-regulation of renal phosphate ion excretion|negative regulation of renal phosphate ion excretion|downregulation of renal phosphate ion excretion|down-regulation of renal phosphate excretion|inhibition of renal phosphate ion excretion						pm	2014-09-01T13:47:10Z						biological_process											owl:Class	
GO:0008001	biolink:NamedThing	obsolete fibrinogen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	fibrinogen			GO:0005577	This term was made obsolete because it does not describe an activity.					True				molecular_function											owl:Class	
GO:0044142	biolink:NamedThing	obsolete positive regulation of growth of symbiont on or near host surface	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass on or near the cells or tissues of the host organism.	got7fsn_ti					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-06T01:35:18Z		True				biological_process											owl:Class	
GO:0010042	biolink:NamedThing	response to manganese ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.	got7fsn_ti	response to manganese													biological_process											owl:Class	
GO:0031401	biolink:NamedThing	positive regulation of protein modification process	Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.	got7fsn_ti	activation of protein modification|up regulation of protein modification|up-regulation of protein modification|upregulation of protein modification|stimulation of protein modification													biological_process											owl:Class	
GO:0110024	biolink:NamedThing	positive regulation of cardiac muscle myoblast proliferation	Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.	got7fsn_ti							kmv	2017-06-29T15:24:16Z						biological_process											owl:Class	
GO:1901051	biolink:NamedThing	atropine biosynthetic process	The chemical reactions and pathways resulting in the formation of atropine.	got7fsn_ti	atropine anabolism|atropine formation|atropine synthesis|atropine biosynthesis						yaf	2012-06-28T04:51:59Z						biological_process											owl:Class	
GO:0006195	biolink:NamedThing	purine nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine nucleotide catabolism|purine nucleotide breakdown|purine nucleotide degradation													biological_process											owl:Class	
GO:0035528	biolink:NamedThing	obsolete UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis	OBSOLETE. The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin.	got7fsn_ti	UDP-N-acetylglucosamine synthesis involved in chitin biosynthesis|UDP-N-acetylglucosamine anabolism involved in chitin biosynthesis|UDP-GlcNAc biosynthetic process involved in chitin biosynthetic process|UDP-GlcNAc biosynthetic process involved in chitin biosynthesis|UDP-GlcNAc biosynthesis involved in chitin biosynthesis|UDP-N-acetylglucosamine formation involved in chitin biosynthesis|UDP-N-acetylglucosamine biosynthetic process involved in chitin biosynthetic process	https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.		bf	2010-05-05T04:49:49Z		True				biological_process											owl:Class	
GO:0006206	biolink:NamedThing	pyrimidine nucleobase metabolic process	The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.	got7fsn_ti	pyrimidine metabolism|pyrimidine metabolic process|pyrimidine base metabolism|pyrimidine base metabolic process													biological_process											owl:Class	
GO:0045655	biolink:NamedThing	regulation of monocyte differentiation	Any process that modulates the frequency, rate or extent of monocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0009679	biolink:NamedThing	hexose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in).	got7fsn_ti	hexose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0071809	biolink:NamedThing	regulation of fever generation by regulation of prostaglandin biosynthesis	Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	got7fsn_ti							mah	2010-09-03T05:07:17Z						biological_process											owl:Class	
GO:0006735	biolink:NamedThing	NADH regeneration	A metabolic process that generates a pool of NADH by the reduction of NAD+.	got7fsn_ti	reduced NAD regeneration|NAD (reduced) regeneration|reduced nicotinamide adenine dinucleotide regeneration													biological_process											owl:Class	
GO:1900335	biolink:NamedThing	positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.	got7fsn_ti	activation of methane biosynthetic process from 3-(methylthio)propionic acid|up regulation of methane biosynthetic process from 3-(methylthio)propionic acid|upregulation of methane biosynthetic process from 3-(methylthio)propionic acid|up-regulation of methane biosynthetic process from 3-(methylthio)propionic acid						tt	2012-04-06T01:56:31Z						biological_process											owl:Class	
GO:0031061	biolink:NamedThing	negative regulation of histone methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.	got7fsn_ti	down-regulation of histone methylation|down regulation of histone methylation|downregulation of histone methylation|inhibition of histone methylation													biological_process											owl:Class	
GO:1903260	biolink:NamedThing	protein localization to mating projection tip	A process in which a protein is transported to, or maintained in, a location within a mating projection tip.	got7fsn_ti	protein localization in mating projection tip|protein localization to conjugation tube tip|protein localisation to mating projection tip|protein localisation in mating projection tip|protein localization to shmoo tip						mah	2014-08-06T13:26:14Z						biological_process											owl:Class	
GO:1900884	biolink:NamedThing	regulation of tridecane biosynthetic process	Any process that modulates the frequency, rate or extent of tridecane biosynthetic process.	got7fsn_ti	regulation of tridecane biosynthesis|regulation of tridecane anabolism|regulation of tridecane synthesis|regulation of tridecane formation						tt	2012-06-13T03:00:31Z						biological_process											owl:Class	
GO:1905586	biolink:NamedThing	negative regulation of outer hair cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process.	got7fsn_ti	downregulation of outer hair cell apoptosis|down regulation of outer hair cell apoptosis|inhibition of outer hair cell apoptosis|down-regulation of outer hair cell apoptotic process|down regulation of cochlear outer hair cell apoptotic process|negative regulation of cochlear outer hair cell apoptotic process|inhibition of outer hair cell apoptotic process|down regulation of outer hair cell apoptotic process|down regulation of cochlear outer hair cell apoptosis|down-regulation of outer hair cell apoptosis|downregulation of outer hair cell apoptotic process|downregulation of cochlear outer hair cell apoptotic process|down-regulation of cochlear outer hair cell apoptosis|inhibition of cochlear outer hair cell apoptotic process|negative regulation of cochlear outer hair cell apoptosis|down-regulation of cochlear outer hair cell apoptotic process|inhibition of cochlear outer hair cell apoptosis|negative regulation of outer hair cell apoptosis|downregulation of cochlear outer hair cell apoptosis						sl	2016-10-24T22:35:43Z						biological_process											owl:Class	
GO:1905335	biolink:NamedThing	regulation of aggrephagy	Any process that modulates the frequency, rate or extent of aggrephagy.	got7fsn_ti							pad	2016-07-26T13:41:46Z						biological_process											owl:Class	
GO:0031658	biolink:NamedThing	obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.	got7fsn_ti	G1/S-specific negative regulation of cyclin-dependent protein kinase activity|G1/S-specific down-regulation of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity involved in G1/S|G1/S-specific inhibition of cyclin-dependent protein kinase activity|G1/S-specific down regulation of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity during G1/S|G1/S-specific downregulation of cyclin-dependent protein kinase activity				The term has been obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:2000379	biolink:NamedThing	positive regulation of reactive oxygen species metabolic process	Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.	got7fsn_ti	positive regulation of reactive oxygen species metabolism|positive regulation of ROS metabolic process						mah	2011-02-11T02:06:57Z						biological_process											owl:Class	
GO:0050937	biolink:NamedThing	regulation of iridophore differentiation	Any process that modulates the frequency, rate or extent of iridophore differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1904335	biolink:NamedThing	regulation of ductus arteriosus closure	Any process that modulates the frequency, rate or extent of ductus arteriosus closure.	got7fsn_ti							sl	2015-06-11T17:45:15Z						biological_process											owl:Class	
GO:2000575	biolink:NamedThing	obsolete negative regulation of microtubule motor activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule motor activity.	got7fsn_ti	negative regulation of kinesin|negative regulation of dynein ATPase activity|negative regulation of kinetochore motor activity|negative regulation of axonemal motor activity|negative regulation of kinesin motor activity|negative regulation of dynein	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140661	bf	2011-04-05T08:36:48Z		True				biological_process											owl:Class	
GO:1990242	biolink:NamedThing	obsolete innate immune response complex	OBSOLETE. A protein complex involved in the innate immune response.	got7fsn_ti	innate immune response complex				This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2013-11-26T13:36:52Z		True				cellular_component											owl:Class	
GO:1905650	biolink:NamedThing	positive regulation of shell calcification	Any process that activates or increases the frequency, rate or extent of shell calcification.	got7fsn_ti	upregulation of shell calcification|up regulation of shell calcification|activation of shell calcification|up-regulation of shell calcification						pga	2016-11-08T16:24:51Z						biological_process											owl:Class	
CHEBI:60119	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001246	biolink:NamedThing	negative regulation of phosphatidylcholine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process.	got7fsn_ti	negative regulation of phosphatidylcholine biosynthesis|negative regulation of phosphatidylcholine synthesis|negative regulation of phosphatidylcholine anabolism|negative regulation of phosphatidylcholine formation						tb	2011-11-28T09:47:47Z						biological_process											owl:Class	
UBERON:0005805	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045474	biolink:NamedThing	obsolete response to ether (sensu Insecta)	OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ether stimulus.	got7fsn_ti	response to ether (sensu Insecta)				This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.	GO:0048150				True				biological_process											owl:Class	
GO:0070608	biolink:NamedThing	regulation of cell wall (1->3)-alpha-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.	got7fsn_ti	regulation of cell wall 1,3-alpha-glucan biosynthesis|regulation of cell wall 1,3-alpha-glucan anabolism|regulation of cell wall alpha-1,3-glucan biosynthesis|regulation of cell wall 1,3-alpha-glucan formation|regulation of cell wall alpha-1,3-glucan anabolism|regulation of cell wall alpha-1,3-glucan biosynthetic process|regulation of cell wall alpha-1,3-glucan synthesis|regulation of cell wall alpha-1,3-glucan formation|regulation of cell wall 1,3-alpha-glucan biosynthetic process|regulation of cell wall 1,3-alpha-glucan synthesis						mah	2009-04-29T01:27:15Z						biological_process											owl:Class	
GO:1901416	biolink:NamedThing	regulation of response to ethanol	Any process that modulates the frequency, rate or extent of response to ethanol.	got7fsn_ti							tt	2012-10-01T16:48:24Z						biological_process											owl:Class	
GO:1904283	biolink:NamedThing	negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.	got7fsn_ti	down-regulation of endogenous peptide antigen processing and presentation via MHC class I|negative regulation of endogenous peptide antigen processing and presentation via MHC class I|down-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|down regulation of endogenous peptide antigen processing and presentation via MHC class I|downregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|downregulation of endogenous peptide antigen processing and presentation via MHC class I|inhibition of endogenous peptide antigen processing and presentation via MHC class I|down regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|inhibition of antigen processing and presentation of endogenous peptide antigen via MHC class I						rl	2015-06-04T12:05:34Z						biological_process											owl:Class	
GO:0086082	biolink:NamedThing	cell adhesive protein binding involved in AV node cell-bundle of His cell communication	Binding to a protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells.	got7fsn_ti	cell adhesive protein binding involved in atrioventricular node cell-bundle of His cell communication						dph	2011-11-22T11:09:37Z						molecular_function											owl:Class	
GO:0033962	biolink:NamedThing	P-body assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.	got7fsn_ti	P body assembly|cytoplasmic mRNA processing body assembly|P body biogenesis	https://github.com/geneontology/go-ontology/issues/19857												biological_process											owl:Class	
CHEBI:34317	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:134269	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900919	biolink:NamedThing	positive regulation of octadecene metabolic process	Any process that activates or increases the frequency, rate or extent of octadecene metabolic process.	got7fsn_ti	up-regulation of octadecene metabolic process|up-regulation of octadecene metabolism|activation of octadecene metabolism|up regulation of octadecene metabolic process|upregulation of octadecene metabolism|activation of octadecene metabolic process|upregulation of octadecene metabolic process|up regulation of octadecene metabolism|positive regulation of octadecene metabolism						tt	2012-06-13T04:26:42Z						biological_process											owl:Class	
GO:0071384	biolink:NamedThing	cellular response to corticosteroid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.	got7fsn_ti							mah	2009-12-11T03:52:07Z						biological_process											owl:Class	
GO:2000991	biolink:NamedThing	regulation of galactomannan catabolic process	Any process that modulates the frequency, rate or extent of galactomannan catabolic process.	got7fsn_ti							tt	2011-08-08T03:15:53Z						biological_process											owl:Class	
GO:0015962	biolink:NamedThing	diadenosine triphosphate metabolic process	The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.	got7fsn_ti	diadenosine triphosphate metabolism													biological_process											owl:Class	
GO:0016146	biolink:NamedThing	obsolete protein-synthesizing GTPase activity, initiation	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	protein-synthesizing GTPase activity, initiation				This term was made obsolete because it contains both process and function information.	GO:0003924|GO:0006413|GO:0003743|GO:0006412				True				molecular_function											owl:Class	
GO:0042187	biolink:NamedThing	p-xylene catabolic process	The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	p-xylene catabolism|para-xylene catabolism|p-xylene breakdown|para-xylene catabolic process|p-xylene degradation													biological_process											owl:Class	
GO:0051147	biolink:NamedThing	regulation of muscle cell differentiation	Any process that modulates the frequency, rate or extent of muscle cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1904331	biolink:NamedThing	regulation of error-prone translesion synthesis	Any process that modulates the frequency, rate or extent of error-prone translesion synthesis.	got7fsn_ti	regulation of error-prone postreplication DNA repair|regulation of mutagenic PRR|regulation of mutagenic postreplication DNA repair						kmv	2015-06-11T16:24:47Z						biological_process											owl:Class	
GO:0010926	biolink:NamedThing	obsolete anatomical structure formation	OBSOLETE. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structure is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	got7fsn_ti	anatomical structure formation				The reason for obsoletion is that the term is confusing - it sounds developmental and has a developmental sounding def, but it is not a child of developmental process and its children included 'cellular component assembly'. The term was created to group together 'cellular component assembly' and 'anatomical structure formation involved in morphogenesis', but we no longer feel that this grouping is useful.	GO:0048646|GO:0022607				True				biological_process											owl:Class	
GO:1901853	biolink:NamedThing	5,6,7,8-tetrahydrosarcinapterin metabolic process	The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin.	got7fsn_ti	5,6,7,8-tetrahydrosarcinapterin metabolism						yaf	2013-01-28T11:47:52Z						biological_process											owl:Class	
GO:0044189	biolink:NamedThing	obsolete host cell microsome	OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic host cells are homogenized and that sediment on centrifugation at 100000 g.	got7fsn_ti	host cell microsome|host cell microsomal membrane				This term was obsoleted because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0033648	jl	2009-10-15T04:04:24Z		True				cellular_component											owl:Class	
GO:0090308	biolink:NamedThing	regulation of DNA methylation-dependent heterochromatin assembly	Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.	got7fsn_ti	regulation of methylation-dependent chromatin silencing						tb	2010-04-09T02:12:53Z						biological_process											owl:Class	
GO:2000999	biolink:NamedThing	positive regulation of cellulose catabolic process	Any process that activates or increases the frequency, rate or extent of cellulose catabolic process.	got7fsn_ti	positive regulation of cellulose degradation|positive regulation of cellulose breakdown|positive regulation of cellulose catabolism						tt	2011-08-08T03:21:30Z						biological_process											owl:Class	
GO:2000152	biolink:NamedThing	regulation of ubiquitin-specific protease activity	Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity.	got7fsn_ti	regulation of UCH2|regulation of deubiquitinase activity|regulation of UBP						tb	2010-10-01T10:09:28Z						biological_process											owl:Class	
GO:1990618	biolink:NamedThing	obsolete ANPR-A:ANP complex	OBSOLETE. The ANPR-A:ANP complex is composed of the hormone AMP bound to the extracellular domain of ANPR-A domain. It is formed in the atrium in response to atrial distension (high blood volume) and leads to guanylate cyclase activity of the ANPR-A receptor, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure. Therefore, ANPR-A:ANP complex plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis.	got7fsn_ti	ANPR-A:ANP complex				An example of this is [ANPR-A:ANP] in [rat] (P18910:P01161-PRO_0000391785) in PMID:15117952 (inferred from direct assay).		ame	2015-01-23T15:17:47Z		True				cellular_component											owl:Class	
GO:0060899	biolink:NamedThing	obsolete regulation of transcription involved in eye field cell fate commitment of camera-type eye	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0060898|GO:0006357	dph	2009-08-13T02:11:48Z		True				biological_process											owl:Class	
GO:0051098	biolink:NamedThing	regulation of binding	Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.	got7fsn_ti														biological_process											owl:Class	
GO:0097287	biolink:NamedThing	7-cyano-7-deazaguanine metabolic process	The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.	got7fsn_ti	7-cyano-7-deazaguanine metabolism						pr	2012-04-25T10:50:50Z						biological_process											owl:Class	
GO:0046478	biolink:NamedThing	lactosylceramide metabolic process	The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.	got7fsn_ti	lactosylceramide metabolism													biological_process											owl:Class	
GO:1900171	biolink:NamedThing	positive regulation of glucocorticoid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway.	got7fsn_ti	up-regulation of glucocorticoid mediated signaling pathway|up regulation of glucocorticoid mediated signaling pathway|upregulation of glucocorticoid mediated signalling|activation of glucocorticoid mediated signaling pathway|activation of glucocorticoid mediated signalling|positive regulation of glucocorticoid mediated signalling|up-regulation of glucocorticoid mediated signalling|upregulation of glucocorticoid mediated signaling pathway|up regulation of glucocorticoid mediated signalling						hjd	2012-03-08T08:33:23Z						biological_process											owl:Class	
GO:1903653	biolink:NamedThing	modulation by symbiont of host cell motility	Modulation of host cell motility by a symbiont of that host.	got7fsn_ti	modulation by symbiont of host cell movement|modulation by symbiont of host cell locomotion|regulation by symbiont of host cell motility						jl	2014-11-24T17:37:56Z						biological_process											owl:Class	
GO:1904591	biolink:NamedThing	positive regulation of protein import	Any process that activates or increases the frequency, rate or extent of protein import.	got7fsn_ti	up regulation of protein import|activation of protein import|up regulation of protein uptake|positive regulation of protein uptake|activation of protein uptake|upregulation of protein import|upregulation of protein uptake|up-regulation of protein uptake|up-regulation of protein import						sl	2015-08-20T21:26:42Z						biological_process											owl:Class	
GO:0021868	biolink:NamedThing	obsolete ventricular zone cell-producing asymmetric radial glial cell division in forebrain	OBSOLETE. The unequal mitotic division of a forebrain radial glial cell that gives rise to a radial glial cell and a ventricular zone cell.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0106189	biolink:NamedThing	obsolete translocase activity acting on hydrons linked to the hydrolysis of a diphosphate	OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a diphosphate.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-07T18:12:33Z		True		EC:7.1.3.-		molecular_function											owl:Class	
CHEBI:61081	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902873	biolink:NamedThing	negative regulation of horizontal cell localization	Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization.	got7fsn_ti	down regulation of horizontal cell localization|downregulation of horizontal cell positioning|down-regulation of horizontal cell positioning|down-regulation of retinal horizontal cell positioning|downregulation of retinal horizontal cell positioning|down regulation of laminar positioning of retinal horizontal cell|inhibition of horizontal cell localisation|downregulation of laminar positioning of retinal horizontal cell|negative regulation of horizontal cell positioning|down regulation of horizontal cell positioning|down regulation of horizontal cell localisation|negative regulation of retinal horizontal cell positioning|negative regulation of horizontal cell localisation|inhibition of horizontal cell positioning|inhibition of horizontal cell localization|negative regulation of laminar positioning of retinal horizontal cell|downregulation of horizontal cell localisation|down-regulation of horizontal cell localisation|down regulation of retinal horizontal cell positioning|inhibition of retinal horizontal cell positioning|down-regulation of laminar positioning of retinal horizontal cell|inhibition of laminar positioning of retinal horizontal cell|downregulation of horizontal cell localization|down-regulation of horizontal cell localization						mr	2014-04-03T15:25:03Z						biological_process											owl:Class	
GO:0005014	biolink:NamedThing	obsolete neurotrophin TRKA receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	neurotrophin TRKA receptor activity				This term was made obsolete because it represents a gene product.	GO:0004714|GO:0048406|GO:0043121|GO:0007165				True				molecular_function											owl:Class	
GO:1904518	biolink:NamedThing	protein localization to cytoplasmic microtubule plus-end	A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end.	got7fsn_ti	protein localisation in cytoplasmic microtubule plus-end|protein localization in cytoplasmic microtubule plus-end|protein localisation to cytoplasmic microtubule plus-end						mah	2015-07-29T14:46:05Z						biological_process											owl:Class	
GO:1903225	biolink:NamedThing	negative regulation of endodermal cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.	got7fsn_ti	down regulation of endodermal cell differentiation|down regulation of endoderm cell differentiation|inhibition of endodermal cell differentiation|downregulation of endodermal cell differentiation|downregulation of endoderm cell differentiation|down-regulation of endodermal cell differentiation|inhibition of endoderm cell differentiation|down-regulation of endoderm cell differentiation|negative regulation of endoderm cell differentiation						als	2014-07-29T13:22:41Z						biological_process											owl:Class	
GO:0060362	biolink:NamedThing	flight involved in flight behavior	Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight.	got7fsn_ti														biological_process											owl:Class	
GO:1903616	biolink:NamedThing	obsolete MAPK cascade involved in axon regeneration	OBSOLETE. Any MAPK cascade that is involved in axon regeneration.	got7fsn_ti	ERK/MAPK cascade involved in axon regeneration|MAPK signal transduction involved in axon regeneration|MAPKKK cascade during sporulation involved in axon regeneration|mitogen-activated protein kinase cascade involved in axon regeneration|MAP kinase cascade involved in axon regeneration|MAPKKK cascade involved in axon regeneration|MAP kinase kinase kinase cascade involved in axon regeneration|MAPK signalling involved in axon regeneration|MAPK signaling involved in axon regeneration	https://github.com/geneontology/go-ontology/issues/14323			This term was obsoleted because it represents a GO-CAM model.		kmv	2014-11-18T19:11:59Z		True				biological_process											owl:Class	
GO:0061186	biolink:NamedThing	negative regulation of silent mating-type cassette heterochromatin assembly	Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.	got7fsn_ti	negative regulation of chromatin silencing at silent mating-type cassette	https://github.com/geneontology/go-ontology/issues/19112					dph	2010-07-14T08:59:11Z						biological_process											owl:Class	
GO:2000363	biolink:NamedThing	positive regulation of prostaglandin-E synthase activity	Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity.	got7fsn_ti	positive regulation of PGH-PGE isomerase activity|positive regulation of PGE isomerase activity|positive regulation of prostaglandin-H2 E-isomerase activity|positive regulation of Prostaglandin-H(2) E-isomerase activity|positive regulation of prostaglandin H-E isomerase activity|positive regulation of prostaglandin endoperoxide E2 isomerase activity|positive regulation of prostaglandin endoperoxide E isomerase activity|positive regulation of endoperoxide isomerase activity|positive regulation of prostaglandin R-prostaglandin E isomerase activity|positive regulation of PGE2 isomerase activity|positive regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity						bf	2011-02-03T04:05:42Z						biological_process											owl:Class	
GO:0010803	biolink:NamedThing	regulation of tumor necrosis factor-mediated signaling pathway	Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.	got7fsn_ti	regulation of TNF signaling|regulation of TNF-mediated signaling pathway|regulation of tumor necrosis factor-mediated signalling pathway													biological_process											owl:Class	
GO:0034139	biolink:NamedThing	regulation of toll-like receptor 3 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway.	got7fsn_ti	regulation of TLR3 signaling pathway|regulation of toll-like receptor 3 signalling pathway													biological_process											owl:Class	
GO:2000779	biolink:NamedThing	regulation of double-strand break repair	Any process that modulates the frequency, rate or extent of double-strand break repair.	got7fsn_ti							bf	2011-06-23T09:28:02Z						biological_process											owl:Class	
GO:1904336	biolink:NamedThing	negative regulation of ductus arteriosus closure	Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure.	got7fsn_ti	down regulation of ductus arteriosus closure|inhibition of ductus arteriosus closure|downregulation of ductus arteriosus closure|down-regulation of ductus arteriosus closure						sl	2015-06-11T17:45:21Z						biological_process											owl:Class	
GO:1902075	biolink:NamedThing	cellular response to salt	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.	got7fsn_ti	cellular response to salinity						mls	2013-04-22T15:42:02Z						biological_process											owl:Class	
GO:0090115	biolink:NamedThing	obsolete C-5 methylation on cytosine involved in chromatin silencing	OBSOLETE. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule that contributes to chromatin silencing.	got7fsn_ti					This term was obsoleted because it represents a molecular function.		tb	2009-12-07T11:55:16Z		True				biological_process											owl:Class	
GO:0045781	biolink:NamedThing	negative regulation of cell budding	Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding.	got7fsn_ti	downregulation of cell budding|negative regulation of budding|down regulation of cell budding|down-regulation of cell budding|inhibition of cell budding													biological_process											owl:Class	
GO:0071306	biolink:NamedThing	cellular response to vitamin E	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.	got7fsn_ti	cellular response to O-Acetyl-alpha-tocopherol|cellular response to DL-alpha-tocopherol acetate|cellular response to DL-alpha-tocopheryl acetate						mah	2009-12-10T04:35:58Z						biological_process											owl:Class	
GO:0015415	biolink:NamedThing	ATPase-coupled phosphate ion transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in).	got7fsn_ti	phosphate transporting ATPase activity|phosphate ion transmembrane-transporting ATPase activity|ATP phosphohydrolase (phosphate-importing)|phosphate-transporting ATPase activity|phosphate ABC transporter|phosphate porter activity|ABC phosphate transporter activity											RHEA:24440|EC:7.3.2.1		molecular_function											owl:Class	
GO:0051473	biolink:NamedThing	glucosylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.	got7fsn_ti	glucosylglycerol formation|glucosylglycerol synthesis|glucosylglycerol anabolism|glucosylglycerol biosynthesis													biological_process											owl:Class	
GO:0007247	biolink:NamedThing	obsolete activation of MAPK (mating sensu Saccharomyces)	OBSOLETE. Upregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.	got7fsn_ti	activation of MAPK (mating sensu Saccharomyces)				This term was made obsolete because it is a gene product specific term.	GO:0000750				True				biological_process											owl:Class	
GO:1902510	biolink:NamedThing	regulation of apoptotic DNA fragmentation	Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.	got7fsn_ti	regulation of DNA catabolic process during apoptosis|regulation of DNA catabolism during apoptosis|regulation of chromatinolysis|regulation of endonucleolytic DNA catabolic process involved in apoptosis|regulation of DNA fragmentation|regulation of DNA fragmentation involved in apoptotic nuclear change				DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).		hjd	2013-11-15T18:28:32Z						biological_process											owl:Class	
GO:0046169	biolink:NamedThing	methanol biosynthetic process	The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.	got7fsn_ti	methanol biosynthesis|methanol anabolism|methanol formation|methanol synthesis													biological_process											owl:Class	
GO:0030808	biolink:NamedThing	regulation of nucleotide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.	got7fsn_ti	regulation of nucleotide anabolism|regulation of nucleotide biosynthesis|regulation of nucleotide synthesis|regulation of nucleotide formation													biological_process											owl:Class	
GO:0044131	biolink:NamedThing	negative regulation of development of symbiont in host	Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti					This term partially replaces the obsolete term 'negative regulation of growth or development of symbiont in host ; GO:0033667'. See also 'negative regulation of growth of symbiont in host ; GO:0044130'.		jl	2009-08-04T02:42:56Z						biological_process											owl:Class	
GO:0034234	biolink:NamedThing	regulation of ascospore wall chitin catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin.	got7fsn_ti	regulation of ascospore wall chitin degradation|regulation of ascospore wall chitin catabolism|regulation of ascospore wall chitin breakdown													biological_process											owl:Class	
GO:1990801	biolink:NamedThing	obsolete protein phosphorylation involved in mitotic spindle assembly	OBSOLETE. Any protein phosphorylation that is involved in mitotic spindle assembly.	got7fsn_ti	protein phosphorylation involved in spindle assembly involved in mitosis|protein amino acid phosphorylation involved in mitotic spindle assembly|protein amino acid phosphorylation involved in spindle assembly involved in mitosis	https://github.com/geneontology/go-ontology/issues/14137			This term has been obsoleted because it represents a GO-CAM model.		rb	2015-07-16T18:36:05Z		True				biological_process											owl:Class	
GO:1901526	biolink:NamedThing	positive regulation of mitophagy	Any process that activates or increases the frequency, rate or extent of mitophagy.	got7fsn_ti	upregulation of macromitophagy|up regulation of macromitophagy|activation of macromitophagy|positive regulation of macromitophagy|up-regulation of macromitophagy						krc	2012-10-22T16:56:57Z						biological_process											owl:Class	
GO:0090050	biolink:NamedThing	positive regulation of cell migration involved in sprouting angiogenesis	Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.	got7fsn_ti							tb	2009-08-07T10:41:09Z						biological_process											owl:Class	
GO:2001305	biolink:NamedThing	xanthone-containing compound metabolic process	The chemical reactions and pathways involving a xanthone-containing compound.	got7fsn_ti	xanthone metabolism|xanthones metabolic process|xanthone-containing compound metabolism|xanthones metabolism						bf	2012-03-14T10:35:38Z						biological_process											owl:Class	
GO:1905856	biolink:NamedThing	negative regulation of pentose-phosphate shunt	Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt.	got7fsn_ti							vw	2017-01-23T14:00:18Z						biological_process											owl:Class	
GO:0031343	biolink:NamedThing	positive regulation of cell killing	Any process that activates or increases the frequency, rate or extent of cell killing.	got7fsn_ti	up regulation of cell killing|stimulation of cell killing|up-regulation of cell killing|activation of cell killing|upregulation of cell killing													biological_process											owl:Class	
GO:0010959	biolink:NamedThing	regulation of metal ion transport	Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2009-05-06T11:40:55Z						biological_process											owl:Class	
GO:0008303	biolink:NamedThing	caspase complex	A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes.	got7fsn_ti	cysteine-type endopeptidase complex				Note that this term was reinstated from obsolete.									cellular_component											owl:Class	
GO:1903863	biolink:NamedThing	P granule assembly	The aggregation, arrangement and bonding together of a set of components to form a P granule.	got7fsn_ti	germline granule formation|polar granule assembly|germline granule assembly|polar granule formation|P granule formation						kmv	2015-02-04T15:27:02Z						biological_process											owl:Class	
GO:0002828	biolink:NamedThing	regulation of type 2 immune response	Any process that modulates the frequency, rate, or extent of a type 2 immune response.	got7fsn_ti	regulation of T-helper 2 type immune response|regulation of Th2 immune response													biological_process											owl:Class	
GO:1905255	biolink:NamedThing	regulation of RNA binding transcription factor activity	Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity.	got7fsn_ti	regulation of transcription factor activity						bf	2016-06-13T11:29:11Z						biological_process											owl:Class	
GO:2001111	biolink:NamedThing	positive regulation of lens epithelial cell proliferation	Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation.	got7fsn_ti							yaf	2011-09-30T02:04:59Z						biological_process											owl:Class	
GO:0140357	biolink:NamedThing	heme export from vacuole to cytoplasm	The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17407					pg	2019-05-28T07:40:48Z						biological_process											owl:Class	
GO:0035630	biolink:NamedThing	bone mineralization involved in bone maturation	The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.	got7fsn_ti					Bone mineralization can also occur after a fracture and as a response to stress; in these cases, consider using the term 'bone mineralization ; GO:0030282'.		bf	2010-12-20T01:57:31Z						biological_process											owl:Class	
CHEBI:46502	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905544	biolink:NamedThing	L-methionine import across plasma membrane	The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-methionine import into cell						mah	2015-01-16T15:03:17Z			GO:1903813			biological_process											owl:Class	
GO:0006044	biolink:NamedThing	N-acetylglucosamine metabolic process	The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.	got7fsn_ti	N-acetylglucosamine metabolism													biological_process											owl:Class	
GO:0045884	biolink:NamedThing	obsolete regulation of survival gene product expression	OBSOLETE. Any process that modulates the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.	got7fsn_ti	regulation of survival gene product activity|regulation of survival gene product expression|regulation of survival gene products				This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc.					True				biological_process											owl:Class	
GO:0043579	biolink:NamedThing	elaioplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored.	got7fsn_ti	elaioplast organization and biogenesis|elaioplast organisation													biological_process											owl:Class	
GO:1902185	biolink:NamedThing	positive regulation of shoot apical meristem development	Any process that activates or increases the frequency, rate or extent of shoot apical meristem development.	got7fsn_ti	up regulation of shoot apical meristem development|up-regulation of promeristem development|activation of primary shoot meristem development|upregulation of shoot apical meristem development|activation of shoot apical meristem development|up-regulation of primary shoot meristem development|up-regulation of shoot apical meristem development|up-regulation of SAM development|up regulation of SAM development|positive regulation of promeristem development|upregulation of primary shoot meristem development|upregulation of promeristem development|activation of SAM development|upregulation of SAM development|up regulation of primary shoot meristem development|positive regulation of SAM development|positive regulation of primary shoot meristem development|activation of promeristem development|up regulation of promeristem development						tb	2013-05-31T16:34:05Z						biological_process											owl:Class	
GO:0043169	biolink:NamedThing	cation binding	Binding to a cation, a charged atom or group of atoms with a net positive charge.	got7fsn_ti														molecular_function											owl:Class	
GO:0062165	biolink:NamedThing	positive regulation of pseudohyphal septin ring assembly	Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation.	got7fsn_ti							dph	2019-11-07T15:55:38Z						biological_process											owl:Class	
GO:0004178	biolink:NamedThing	obsolete leucyl aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Xbb may be Pro.	got7fsn_ti	cathepsin III|aminopeptidase II|proteinates FTBL|peptidase S activity|leucyl aminopeptidase activity|cytosol aminopeptidase activity|leucinaminopeptidase activity|L-leucine aminopeptidase activity|FTBL proteins|leucine aminopeptidase activity|leucyl peptidase activity|leucinamide aminopeptidase activity				This term was made obsolete because it represents a gene product.	GO:0004177|GO:0008235				True		EC:3.4.11.1|MetaCyc:3.4.11.1-RXN		molecular_function											owl:Class	
GO:1901758	biolink:NamedThing	butirosin biosynthetic process	The chemical reactions and pathways resulting in the formation of butirosin.	got7fsn_ti	butirosin synthesis|butirosin anabolism|butirosin formation|butirosin biosynthesis						yaf	2013-01-14T11:36:27Z						biological_process											owl:Class	
GO:2001059	biolink:NamedThing	D-tagatose 6-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate.	got7fsn_ti	D-tagatose 6-phosphate catabolism						jl	2011-09-09T03:21:33Z				UniPathway:UPA00704		biological_process											owl:Class	
GO:0030801	biolink:NamedThing	obsolete positive regulation of cyclic nucleotide metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.	got7fsn_ti	positive regulation of cyclic nucleotide metabolism|up-regulation of cyclic nucleotide metabolic process|upregulation of cyclic nucleotide metabolic process|activation of cyclic nucleotide metabolic process|stimulation of cyclic nucleotide metabolic process|up regulation of cyclic nucleotide metabolic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0009215	biolink:NamedThing	purine deoxyribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:1903936	biolink:NamedThing	cellular response to sodium arsenite	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	got7fsn_ti							sl	2015-02-12T20:54:53Z						biological_process											owl:Class	
GO:0090690	biolink:NamedThing	obsolete heteroreceptor complex	OBSOLETE. A receptor complex that consists of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger. The formation of the higher level complex initiates a change in cell function.	got7fsn_ti					This term was obsoleted as it was created in error.		tb	2016-08-24T09:47:15Z		True				cellular_component											owl:Class	
GO:0034129	biolink:NamedThing	positive regulation of MyD88-independent toll-like receptor signaling pathway	Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.	got7fsn_ti	positive regulation of MyD88-independent toll-like receptor|positive regulation of MyD88-independent toll-like receptor signalling pathway|positive regulation of MyD88-independent TLR signaling pathway													biological_process											owl:Class	
GO:0075309	biolink:NamedThing	obsolete negative regulation of growth or development of symbiont on or near host surface	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	got7fsn_ti	negative regulation of growth or development of symbiont on or near host surface				This term was made obsolete because it contained a conjunction (or).					True				biological_process											owl:Class	
GO:0051028	biolink:NamedThing	mRNA transport	The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:2001255	biolink:NamedThing	positive regulation of histone H3-K36 trimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation.	got7fsn_ti							pr	2011-12-06T07:38:24Z						biological_process											owl:Class	
GO:0019795	biolink:NamedThing	obsolete nonprotein amino acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of any amino acid that does not normally occur as a constituent residue of proteins.	got7fsn_ti	nonprotein amino acid formation|nonprotein amino acid biosynthesis|nonprotein amino acid biosynthetic process|nonprotein amino acid anabolism|nonprotein amino acid synthesis			GO:0008652	This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity.					True				biological_process											owl:Class	
GO:0075228	biolink:NamedThing	positive regulation of encysted zoospore germination	Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination.	got7fsn_ti	positive regulation of encysted zoospore germination on or near host													biological_process											owl:Class	
GO:1902078	biolink:NamedThing	positive regulation of lateral motor column neuron migration	Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration.	got7fsn_ti	up regulation of lateral motor column neuron migration|activation of lateral motor column neuron migration|upregulation of lateral motor column neuron migration|up-regulation of lateral motor column neuron migration						pr	2013-04-23T14:42:28Z						biological_process											owl:Class	
GO:1902312	biolink:NamedThing	negative regulation of copper ion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport.	got7fsn_ti	negative regulation of copper ion membrane transport|negative regulation of copper cation transmembrane transport|down-regulation of copper ion membrane transport|downregulation of copper ion transmembrane transport|down regulation of copper ion membrane transport|downregulation of copper ion membrane transport|inhibition of copper cation transmembrane transport|inhibition of copper ion transmembrane transport|downregulation of copper cation transmembrane transport|down-regulation of copper ion transmembrane transport|down regulation of copper ion transmembrane transport|inhibition of copper ion membrane transport|down regulation of copper cation transmembrane transport|down-regulation of copper cation transmembrane transport						di	2013-07-19T20:59:37Z						biological_process											owl:Class	
GO:0097199	biolink:NamedThing	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.	got7fsn_ti	cysteine-type endopeptidase activity involved in apoptotic signalling pathway|apical caspase activity|activator caspase activity|initiator caspase activity				Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases.		pr	2011-12-12T01:43:00Z						molecular_function											owl:Class	
PR:000001457	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000401	biolink:NamedThing	regulation of lymphocyte migration	Any process that modulates the frequency, rate or extent of lymphocyte migration.	got7fsn_ti							mah	2011-02-23T10:45:19Z						biological_process											owl:Class	
GO:1905205	biolink:NamedThing	positive regulation of connective tissue replacement	Any process that activates or increases the frequency, rate or extent of connective tissue replacement.	got7fsn_ti	activation of connective tissue replacement|up regulation of connective tissue replacement|up-regulation of connective tissue replacement|upregulation of connective tissue replacement						bc	2016-05-17T09:54:35Z						biological_process											owl:Class	
GO:1903013	biolink:NamedThing	response to differentiation-inducing factor 1	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.	got7fsn_ti	response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one|response to DIF-1|response to DIF1|DIF-1						rjd	2014-05-14T16:18:11Z						biological_process											owl:Class	
GO:1903675	biolink:NamedThing	negative regulation of cap-dependent translational initiation	Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation.	got7fsn_ti	down regulation of cap-dependent translational initiation|inhibition of cap-dependent translational initiation|down-regulation of cap-dependent translational initiation|downregulation of cap-dependent translational initiation						bf	2014-11-27T19:50:31Z						biological_process											owl:Class	
GO:0046973	biolink:NamedThing	obsolete histone lysine N-methyltransferase activity (H3-K24 specific)	OBSOLETE. Catalysis of the addition of a methyl group onto lysine at position 24 of the histone H3 protein.	got7fsn_ti	histone lysine N-methyltransferase activity (H3-K24 specific)				This term was made obsolete because there is no lysine at position 24 of histone H3.	GO:0042800				True				molecular_function											owl:Class	
GO:0033689	biolink:NamedThing	negative regulation of osteoblast proliferation	Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.	got7fsn_ti	inhibition of osteoblast proliferation|down-regulation of osteoblast proliferation|downregulation of osteoblast proliferation|down regulation of osteoblast proliferation													biological_process											owl:Class	
GO:0006043	biolink:NamedThing	glucosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.	got7fsn_ti	glucosamine degradation|chitosamine catabolism|glucosamine breakdown|chitosamine catabolic process|glucosamine catabolism											MetaCyc:GLUAMCAT-PWY		biological_process											owl:Class	
GO:0019849	biolink:NamedThing	obsolete cytotoxin activity	OBSOLETE. Acts as to cause injury to other living cells.	got7fsn_ti	cytotoxin activity				This term was made obsolete because it represents a class of gene products.	GO:0090729				True				molecular_function											owl:Class	
GO:0098659	biolink:NamedThing	inorganic cation import across plasma membrane	The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	inorganic cation import into cell													biological_process											owl:Class	
GO:0023060	biolink:NamedThing	obsolete signal transmission	OBSOLETE. The process in which a signal is released and/or conveyed from one location to another.	got7fsn_ti	signal transmission				This term was made obsolete because it was an unnecessary grouping term.	GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0097289	biolink:NamedThing	alpha-ribazole metabolic process	The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).	got7fsn_ti	alpha-ribazole metabolism						pr	2012-04-25T11:49:24Z						biological_process											owl:Class	
GO:1904738	biolink:NamedThing	vascular associated smooth muscle cell migration	The orderly movement of a vascular associated smooth muscle cell from one site to another.	got7fsn_ti	vascular smooth muscle cell migration						rph	2015-10-15T09:56:00Z						biological_process											owl:Class	
GO:1905532	biolink:NamedThing	regulation of leucine import across plasma membrane	Any process that modulates the frequency, rate or extent of leucine import across plasma membrane.	got7fsn_ti	regulation of L-leucine import into cell|regulation of leucine import into cell						vw	2014-06-25T13:09:51Z			GO:1903128			biological_process											owl:Class	
GO:0048237	biolink:NamedThing	rough endoplasmic reticulum lumen	The volume enclosed by the membranes of the rough endoplasmic reticulum.	got7fsn_ti	RER lumen|rough ER lumen											NIF_Subcellular:sao1819509473		cellular_component											owl:Class	
GO:0100034	biolink:NamedThing	obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates 4,6-pyruvylated galactose residue biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0032215	biolink:NamedThing	positive regulation of telomere maintenance via semi-conservative replication	Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.	got7fsn_ti	upregulation of telomere maintenance via semi-conservative replication|stimulation of telomere maintenance via semi-conservative replication|up regulation of telomere maintenance via semi-conservative replication|up-regulation of telomere maintenance via semi-conservative replication|activation of telomere maintenance via semi-conservative replication													biological_process											owl:Class	
GO:0010745	biolink:NamedThing	negative regulation of macrophage derived foam cell differentiation	Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	got7fsn_ti														biological_process											owl:Class	
GO:0033509	biolink:NamedThing	glutamate catabolic process to propionate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate.	got7fsn_ti	glutamate degradation to propionate|glutamate breakdown to propionate											MetaCyc:PWY-5088		biological_process											owl:Class	
GO:0060723	biolink:NamedThing	regulation of cell proliferation involved in embryonic placenta development	Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.	got7fsn_ti							dph	2009-06-12T12:50:23Z						biological_process											owl:Class	
CHEBI:25696	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900682	biolink:NamedThing	octadecene biosynthetic process	The chemical reactions and pathways resulting in the formation of octadecene.	got7fsn_ti	1-octadecene biosynthetic process|octadecene synthesis|octadecene formation|octadecene biosynthesis|octadecene anabolism						tt	2012-05-22T04:28:49Z						biological_process											owl:Class	
GO:0072466	biolink:NamedThing	obsolete detection of stimulus involved in cell shape checkpoint	OBSOLETE. The series of events in which information about aspects of cell polarity control is received and converted into a molecular signal, contributing to a cell shape checkpoint.	got7fsn_ti	sensing involved in cell shape checkpoint|cell shape checkpoint sensor process|cell shape checkpoint sensor mechanism				This term was made obsolete because it was ambiguous.		mah	2010-12-09T11:43:58Z		True				biological_process											owl:Class	
GO:1905136	biolink:NamedThing	dethiobiotin import across plasma membrane	The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	dethiobiotin import into cell|dethiobiotin import						jl	2012-12-06T13:06:28Z			GO:0044757|GO:1901690			biological_process											owl:Class	
GO:0010661	biolink:NamedThing	positive regulation of muscle cell apoptotic process	Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.	got7fsn_ti	positive regulation of muscle cell apoptosis													biological_process											owl:Class	
GO:1900355	biolink:NamedThing	negative regulation of methanofuran metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process.	got7fsn_ti	down regulation of methanofuran metabolism|down-regulation of methanofuran metabolic process|inhibition of methanofuran metabolic process|downregulation of methanofuran metabolic process|down regulation of methanofuran metabolic process|negative regulation of methanofuran metabolism|down-regulation of methanofuran metabolism|downregulation of methanofuran metabolism|inhibition of methanofuran metabolism						tt	2012-04-06T02:15:53Z						biological_process											owl:Class	
GO:0030035	biolink:NamedThing	microspike assembly	Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell.	got7fsn_ti	microspike biogenesis|microspike formation|microspike biosynthesis				Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. For the assembly of filopodia, use 'filopodium assembly ; GO:0046847'.									biological_process											owl:Class	
GO:0006202	biolink:NamedThing	GMP catabolic process to guanine	The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine.	got7fsn_ti	GMP breakdown to guanine|GMP degradation to guanine													biological_process											owl:Class	
GO:2000473	biolink:NamedThing	positive regulation of hematopoietic stem cell migration	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.	got7fsn_ti	positive regulation of hemopoietic stem cell migration						bf	2011-03-09T09:35:25Z						biological_process											owl:Class	
GO:1990568	biolink:NamedThing	obsolete MIS18 complex	OBSOLETE. A centromere complex assembly protein that is required for the deposition of CENP-A on the centromere. The Mis18 complex localizes to centromeres just prior to the pre-nucleosomal HJURP/CENP-A/H4 complex and is absolutely required for the CENP-A-specific chaperone, Holliday junction recognition protein (HJURP) to reach the centromeres. Plk1 phosphorylation activates Mis18 complex recruitment to the centromeres during G1. CDK phosphorylation of MISBP1 during G2 and mitosis, prior to the metaphase-to-anaphase transition, negatively regulates complex assembly.	got7fsn_ti	MIS18 complex				An example of this is MIS18A in human (Q9NYP9) in PMID:25036634 (inferred from physical interaction).		bhm	2014-11-27T10:52:20Z		True				cellular_component											owl:Class	
GO:0042489	biolink:NamedThing	negative regulation of odontogenesis of dentin-containing tooth	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx.	got7fsn_ti	negative regulation of odontogenesis of dentine-containing teeth|down-regulation of odontogenesis|down regulation of odontogenesis|inhibition of odontogenesis|downregulation of odontogenesis|negative regulation of odontogenesis|negative regulation of odontogenesis of dentine-containing tooth													biological_process											owl:Class	
GO:1901157	biolink:NamedThing	neomycin catabolic process	The chemical reactions and pathways resulting in the breakdown of neomycin.	got7fsn_ti	neomycin degradation|neomycin breakdown|neomycin catabolism						yaf	2012-07-17T04:28:20Z						biological_process											owl:Class	
GO:1990415	biolink:NamedThing	Pex17p-Pex14p docking complex	A protein complex involved in the peroxisomal import machinery. In S. cerevisiae, this complex contains the proteins Pex17p, Pex14p, Pex19, and Pex13p.	got7fsn_ti							rb	2014-07-10T21:43:31Z						cellular_component											owl:Class	
GO:0150152	biolink:NamedThing	negative regulation of interleukin-17A production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production.	got7fsn_ti	negative regulation of interleukin-17A biosynthetic process						bc	2019-12-11T07:45:24Z						biological_process											owl:Class	
GO:0002879	biolink:NamedThing	positive regulation of acute inflammatory response to non-antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.	got7fsn_ti	activation of acute inflammatory response to non-antigenic stimulus|stimulation of acute inflammatory response to non-antigenic stimulus|up regulation of acute inflammatory response to non-antigenic stimulus|upregulation of acute inflammatory response to non-antigenic stimulus|up-regulation of acute inflammatory response to non-antigenic stimulus													biological_process											owl:Class	
GO:1904583	biolink:NamedThing	response to polyamine macromolecule	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.	got7fsn_ti	response to polyamine|response to polyamines						sl	2015-08-20T14:35:26Z						biological_process											owl:Class	
GO:0015448	biolink:NamedThing	obsolete type III protein (virulence-related) secretor activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	type III protein (virulence-related) secretor activity				This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True				molecular_function											owl:Class	
GO:0120162	biolink:NamedThing	positive regulation of cold-induced thermogenesis	Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.	got7fsn_ti	positive regulation of CIT						krc	2018-05-14T17:14:51Z						biological_process											owl:Class	
GO:1900482	biolink:NamedThing	positive regulation of diacylglycerol biosynthetic process	Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process.	got7fsn_ti	upregulation of diacylglycerol biosynthesis|upregulation of diacylglycerol synthesis|up-regulation of diacylglycerol formation|positive regulation of diacylglycerol biosynthesis|up-regulation of diacylglycerol biosynthesis|upregulation of diacylglycerol formation|activation of diacylglycerol biosynthesis|activation of diacylglycerol biosynthetic process|positive regulation of diacylglycerol synthesis|positive regulation of diacylglycerol anabolism|activation of diacylglycerol anabolism|up regulation of diacylglycerol biosynthetic process|up-regulation of diacylglycerol anabolism|activation of diacylglycerol synthesis|up regulation of diacylglycerol synthesis|up-regulation of diacylglycerol biosynthetic process|upregulation of diacylglycerol anabolism|positive regulation of diacylglycerol formation|up regulation of diacylglycerol biosynthesis|up regulation of diacylglycerol anabolism|up-regulation of diacylglycerol synthesis|upregulation of diacylglycerol biosynthetic process|activation of diacylglycerol formation|up regulation of diacylglycerol formation						al	2012-05-02T10:09:18Z						biological_process											owl:Class	
GO:1902381	biolink:NamedThing	11-oxo-beta-amyrin metabolic process	The chemical reactions and pathways involving 11-oxo-beta-amyrin.	got7fsn_ti	11-oxo-beta-amyrin metabolism						ms	2013-09-03T12:55:29Z						biological_process											owl:Class	
GO:0071319	biolink:NamedThing	cellular response to benzoic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.	got7fsn_ti							mah	2009-12-10T05:10:20Z						biological_process											owl:Class	
GO:0018888	biolink:NamedThing	3-chloroacrylic acid metabolic process	The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid.	got7fsn_ti	3-chloroacrylic acid metabolism											UM-BBD_pathwayID:caa		biological_process											owl:Class	
GO:0032175	biolink:NamedThing	mating projection septin ring	A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip.	got7fsn_ti														cellular_component											owl:Class	
GO:0009491	biolink:NamedThing	obsolete redox-active disulfide bond electron carrier	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	redox-active disulfide bond electron carrier|redox-active disulphide bond electron carrier			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:1902272	biolink:NamedThing	regulation of (R)-carnitine transmembrane transport	Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport.	got7fsn_ti							mcc	2013-07-01T13:13:11Z						biological_process											owl:Class	
GO:0052328	biolink:NamedThing	obsolete interaction with symbiont via protein secreted by type III secretion system	OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type III secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with symbiont via protein secreted by type III secretion system				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:2000222	biolink:NamedThing	positive regulation of pseudohyphal growth	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth.	got7fsn_ti							mah	2010-11-03T04:37:03Z						biological_process											owl:Class	
CHEBI:26389	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140413	biolink:NamedThing	zinc:bicarbonate:selenite symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) + HO3Se-(out) = zinc(in) + HCO3-(in) + HO3Se-(out).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18345					pg	2020-01-07T18:58:12Z						molecular_function											owl:Class	
CHEBI:39128	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071580	biolink:NamedThing	regulation of zinc ion transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.	got7fsn_ti	regulation of zinc ion membrane transport						mah	2010-01-28T03:05:53Z						biological_process											owl:Class	
GO:0052398	biolink:NamedThing	obsolete induction by organism of symbiont phytoalexin production	OBSOLETE. The activation by an organism of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of symbiont phytoalexin production|induction by organism of symbiont phytoalexin production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1904845	biolink:NamedThing	cellular response to L-glutamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.	got7fsn_ti							sl	2015-12-07T19:39:24Z						biological_process											owl:Class	
GO:0120252	biolink:NamedThing	hydrocarbon metabolic process	The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.	got7fsn_ti	hydrocarbon metabolism	https://github.com/geneontology/go-ontology/issues/19842					krc	2020-09-02T20:47:28Z						biological_process											owl:Class	
GO:0042838	biolink:NamedThing	D-glucarate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate.	got7fsn_ti	D-glucarate catabolism|D-glucarate degradation|saccharate catabolism|saccharate catabolic process|D-glucarate breakdown													biological_process											owl:Class	
GO:0030593	biolink:NamedThing	neutrophil chemotaxis	The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	got7fsn_ti														biological_process											owl:Class	
GO:0140481	biolink:NamedThing	ABC-type iron-sulfur cluster transporter activity	Catalysis of the reaction: ATP + H2O + iron-sulfur cluster(in) = ADP + phosphate + iron-sulfur cluster(out).	got7fsn_ti	ATPase-coupled Fe-S cluster transmembrane transporter activity|ATPase-coupled iron-sulfur cluster transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/19685					pg	2020-06-25T17:41:01Z				TC:3.A.1.210.1		molecular_function											owl:Class	
GO:0046089	biolink:NamedThing	cytosine biosynthetic process	The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.	got7fsn_ti	cytosine synthesis|cytosine formation|cytosine biosynthesis|cytosine anabolism													biological_process											owl:Class	
GO:1901364	biolink:NamedThing	funalenone metabolic process	The chemical reactions and pathways involving funalenone.	got7fsn_ti	funalenone metabolism						di	2012-09-17T18:24:23Z						biological_process											owl:Class	
GO:0098811	biolink:NamedThing	obsolete transcriptional repressor activity, RNA polymerase II activating transcription factor binding	OBSOLETE. Binding to an RNA polymerase II activating transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription.	got7fsn_ti	RNA polymerase II activating transcription factor binding transcription repressor activity|RNA polymerase II transcription repressor activity|RNA polymerase II activating transcription factor binding transcription factor activity involved in negative regulation of transcription	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0001227	krc	2011-08-25T02:12:30Z		True				molecular_function											owl:Class	
GO:0150119	biolink:NamedThing	negative regulation of protein localization to cell-cell junction	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction.	got7fsn_ti	negative regulation of protein localisation to cell-cell junction						bc	2019-11-21T13:53:34Z						biological_process											owl:Class	
GO:2001095	biolink:NamedThing	mannotriose transport	The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:04:52Z						biological_process											owl:Class	
GO:0033666	biolink:NamedThing	obsolete positive regulation of growth or development of symbiont in host	OBSOLETE. Any process by which the symbiont activates, maintains or increases its size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti	up-regulation of growth or development of organism within host|positive regulation of growth or development of symbiont in host|positive regulation of invasive growth|upregulation of growth or development of organism within host|positive regulation of growth or development of symbiont within host|up regulation of growth or development of organism within host				This term was made obsolete because it contained a conjunction (or).	GO:0044129				True				biological_process											owl:Class	
GO:0070982	biolink:NamedThing	L-asparagine metabolic process	The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.	got7fsn_ti	L-asparagine metabolism						mah	2009-10-27T01:03:46Z						biological_process											owl:Class	
CL:0000097	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035618	biolink:NamedThing	root hair	A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall.	got7fsn_ti					This term is a child of 'cell projection' and not 'cell hair' to distinguish it from animal cell hairs, which are morphologically distinct.		bf	2010-12-03T01:42:40Z						cellular_component											owl:Class	
GO:1901425	biolink:NamedThing	response to formic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus.	got7fsn_ti							tt	2012-10-01T18:43:05Z						biological_process											owl:Class	
GO:2001315	biolink:NamedThing	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process	The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.	got7fsn_ti	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose formation|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthesis|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose synthesis|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose anabolism						pr	2012-03-22T01:20:05Z						biological_process											owl:Class	
GO:0004009	biolink:NamedThing	obsolete ATP-binding cassette (ABC) transporter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ATP-binding cassette (ABC) transporter activity				This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.	GO:0042626|GO:0043190				True				molecular_function											owl:Class	
CHEBI:17668	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000455	biolink:NamedThing	regulation of T-helper 17 cell extravasation	Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation.	got7fsn_ti							bf	2011-03-04T10:49:51Z						biological_process											owl:Class	
GO:1900112	biolink:NamedThing	regulation of histone H3-K9 trimethylation	Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation.	got7fsn_ti							bf	2012-02-21T09:09:49Z						biological_process											owl:Class	
GO:0019718	biolink:NamedThing	obsolete rough microsome	OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum membranes and studded with ribosomes on the outside.	got7fsn_ti	rough microsome				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005791				True				cellular_component											owl:Class	
GO:0046085	biolink:NamedThing	adenosine metabolic process	The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.	got7fsn_ti	adenosine metabolism													biological_process											owl:Class	
GO:0090448	biolink:NamedThing	glucosinolate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in).	got7fsn_ti	glucosinolate:hydrogen symporter activity						tb	2012-09-07T16:10:37Z						molecular_function											owl:Class	
GO:0097079	biolink:NamedThing	selenite:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in).	got7fsn_ti	selenite:H+ symporter activity|selenite:hydrogen symporter activity						pr	2011-06-17T10:01:11Z						molecular_function											owl:Class	
GO:0061372	biolink:NamedThing	activin receptor signaling pathway involved in heart jogging	A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging.	got7fsn_ti	activin receptor signalling pathway involved in heart jogging						dph	2010-11-03T02:24:46Z						biological_process											owl:Class	
GO:0140576	biolink:NamedThing	ascorbate homeostasis	Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell.	got7fsn_ti	cellular ascorbate homeostasis	https://github.com/geneontology/go-ontology/issues/20602|https://github.com/geneontology/go-ontology/issues/20672					pg	2021-01-07T16:50:44Z						biological_process											owl:Class	
GO:0070322	biolink:NamedThing	obsolete negative regulation of translation in response to nitrogen starvation	OBSOLETE. Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen.	got7fsn_ti	inhibition of translation in response to nitrogen starvation|down-regulation of translation in response to nitrogen starvation|down regulation of translation in response to nitrogen starvation|downregulation of translation in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/19092			This term was obsoleted because it was redundant with GO:1903574 ; negative regulation of cellular response to amino acid starvation.	GO:1903574				True				biological_process											owl:Class	
GO:1901905	biolink:NamedThing	response to tamsulosin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus.	got7fsn_ti							hp	2013-02-13T10:14:41Z						biological_process											owl:Class	
GO:0010963	biolink:NamedThing	regulation of L-arginine import	Any process that modulates the frequency, rate or extent of L-arginine import. L-arginine import is the directed movement of L-arginine, the L-enantiomer of 2-amino-5-guanidinopentanoic acid, into a cell or organelle.	got7fsn_ti							tb	2009-05-20T11:20:18Z						biological_process											owl:Class	
GO:0021922	biolink:NamedThing	Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division.	got7fsn_ti	Wnt receptor signalling pathway involved in regulation of cell proliferation in dorsal spinal cord|Wnt-activated signaling pathway involved in regulation of cell proliferation in dorsal spinal cord|Wnt receptor signaling pathway involved in regulation of cell proliferation in dorsal spinal cord													biological_process											owl:Class	
GO:0052528	biolink:NamedThing	obsolete upregulation by organism of symbiont programmed cell death	OBSOLETE. Any process by which an organism increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	enhancement of symbiont programmed cell death by organism|upregulation by organism of symbiont programmed cell death				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0044044	biolink:NamedThing	obsolete interaction with host via substance in symbiont surface	OBSOLETE. An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that these terms conflate a process and the mechanism of secretion of the compound mediating the process.					True				biological_process											owl:Class	
GO:0061850	biolink:NamedThing	growth cone leading edge	That part of the growth cone which represents the distal part of the structure.	got7fsn_ti														cellular_component											owl:Class	
GO:0001636	biolink:NamedThing	obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True				molecular_function											owl:Class	
GO:1901101	biolink:NamedThing	gramicidin S metabolic process	The chemical reactions and pathways involving gramicidin S.	got7fsn_ti	gramicidin S metabolism						yaf	2012-07-11T02:30:26Z						biological_process											owl:Class	
GO:0007578	biolink:NamedThing	obsolete aging dependent sterility (sensu Saccharomyces)	OBSOLETE. A haploid's inability to mate due to the loss of silencing at the mating-type loci, resulting in expression of both of the normally silent mating-type cassettes.	got7fsn_ti	aging dependent sterility (sensu Saccharomyces)				This term was made obsolete because it reflected a trait or phenotype.	GO:0030466				True				biological_process											owl:Class	
GO:1900348	biolink:NamedThing	regulation of methane biosynthetic process from methylamine	Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine.	got7fsn_ti							tt	2012-04-06T02:11:54Z						biological_process											owl:Class	
GO:0043901	biolink:NamedThing	obsolete negative regulation of multi-organism process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.	got7fsn_ti					This term was obsoleted because it is an unnecessary grouping term.					True				biological_process											owl:Class	
GO:0090019	biolink:NamedThing	obsolete regulation of transcription involved in anterior neural plate formation	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the anterior neural plate.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0090017	tb	2009-07-29T11:38:28Z		True				biological_process											owl:Class	
GO:1905748	biolink:NamedThing	hard palate morphogenesis	The developmental process by which a hard palate is generated and organized.	got7fsn_ti	palatum durum morphogenesis						pga	2016-12-09T12:22:24Z						biological_process											owl:Class	
GO:2000863	biolink:NamedThing	positive regulation of estrogen secretion	Any process that activates or increases the frequency, rate or extent of estrogen secretion.	got7fsn_ti	positive regulation of oestrogen secretion						bf	2011-07-26T08:48:31Z						biological_process											owl:Class	
GO:0015462	biolink:NamedThing	ABC-type protein transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).	got7fsn_ti	protein-transporting ATPase activity|protein ABC transporter|ABC-type protein transmembrane transporter activity|ATPase-coupled protein transmembrane transporter activity|pilin/fimbrilin exporter activity|protein-transmembrane transporting ATPase activity				Enzymes with this activity include bacterial enzymes dedicated to the secretion of one or several closely related proteins belonging to the toxin, protease and lipase families, for example alpha-hemolysin, cyclolysin, colicin V, siderophores, bacteriocin, subtilin, competence factor and pediocin (from EC:7.4.2.5).							EC:7.4.2.5		molecular_function											owl:Class	
GO:1903780	biolink:NamedThing	negative regulation of cardiac conduction	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.	got7fsn_ti	downregulation of cardiac conduction|inhibition of cardiac conduction|down regulation of cardiac conduction|down-regulation of cardiac conduction						rph	2015-01-07T13:20:20Z						biological_process											owl:Class	
GO:0001149	biolink:NamedThing	obsolete transcription factor activity, bacterial-type RNA polymerase termination site sequence-specific binding	OBSOLETE. Binding to a sequence of DNA that is a termination site for bacterial-type RNA polymerase in order to promote transcription termination by bacterial-type RNA polymerase.	got7fsn_ti	bacterial-type RNA polymerase termination site sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16730					krc	2011-01-27T03:08:41Z		True				molecular_function											owl:Class	
GO:0051279	biolink:NamedThing	regulation of release of sequestered calcium ion into cytosol	Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.	got7fsn_ti	regulation of release of sequestered calcium ion (Ca2+)|regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|regulation of calcium ion (Ca2+) mobilization|regulation of calcium mobilization|regulation of release of stored calcium ion (Ca2+) into cytosol|regulation of cytoplasmic release of stored calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+) into cytoplasm|regulation of release of stored calcium ion (Ca2+)													biological_process											owl:Class	
GO:0009253	biolink:NamedThing	peptidoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.	got7fsn_ti	peptidoglycan breakdown|murein catabolism|peptidoglycan catabolism|murein catabolic process|peptidoglycan degradation										GO:0009286			biological_process											owl:Class	
GO:0007116	biolink:NamedThing	regulation of cell budding	Any process that modulates the frequency, rate or extent of the formation and growth of cell buds.	got7fsn_ti	regulation of budding													biological_process											owl:Class	
GO:1905573	biolink:NamedThing	ganglioside GM1 binding	Binding to ganglioside GM1.	got7fsn_ti							pga	2016-10-19T10:57:28Z						molecular_function											owl:Class	
UBERON:0000204	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070445	biolink:NamedThing	regulation of oligodendrocyte progenitor proliferation	Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.	got7fsn_ti	regulation of oligodendrocyte precursor proliferation													biological_process											owl:Class	
GO:1904214	biolink:NamedThing	positive regulation of iodide transmembrane transport	Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport.	got7fsn_ti	up-regulation of iodide transmembrane transport|upregulation of iodide transmembrane transport|up regulation of iodide transmembrane transport|activation of iodide transmembrane transport						sl	2015-05-14T19:00:14Z						biological_process											owl:Class	
GO:0019717	biolink:NamedThing	obsolete synaptosome	OBSOLETE. Any of the discrete particles (nerve-ending particles) formed from the clublike presynaptic nerve endings that resist disruption and are snapped or torn off their attachments when brain tissue is homogenized in media isosmotic to plasma.	got7fsn_ti	synaptosome				This term was made obsolete because it refers to a result of cell homogenization and not a bona fide cellular component.	GO:0043005				True		Wikipedia:Synaptosome		cellular_component											owl:Class	
GO:2001263	biolink:NamedThing	regulation of C-C chemokine binding	Any process that modulates the frequency, rate or extent of C-C chemokine binding.	got7fsn_ti							yaf	2011-12-09T01:13:54Z						biological_process											owl:Class	
GO:0061065	biolink:NamedThing	regulation of dauer larval development	Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.	got7fsn_ti							dph	2010-03-11T01:07:07Z						biological_process											owl:Class	
OBO:OBA_0000119	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905804	biolink:NamedThing	positive regulation of cellular response to manganese ion	Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion.	got7fsn_ti	up-regulation of cellular response to manganese ion|up regulation of cellular response to manganese ion|upregulation of cellular response to manganese|upregulation of cellular response to manganese ion|up regulation of cellular response to manganese|activation of cellular response to manganese|up-regulation of cellular response to manganese|positive regulation of cellular response to manganese|activation of cellular response to manganese ion						pga	2017-01-11T14:59:57Z						biological_process											owl:Class	
GO:0033085	biolink:NamedThing	negative regulation of T cell differentiation in thymus	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.	got7fsn_ti	negative regulation of thymocyte cell differentiation|negative regulation of thymic T cell differentiation|negative regulation of thymocyte differentiation|negative regulation of T cell development in thymus				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0042432	biolink:NamedThing	indole biosynthetic process	The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).	got7fsn_ti	indole biosynthesis|indole anabolism|indole formation|indole synthesis													biological_process											owl:Class	
GO:0061885	biolink:NamedThing	positive regulation of mini excitatory postsynaptic potential	Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.	got7fsn_ti							dph	2017-05-30T15:46:16Z						biological_process											owl:Class	
GO:0009495	biolink:NamedThing	obsolete thioredoxin-like 2Fe-2S ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	thioredoxin-like 2Fe-2S ferredoxin			GO:0009055	This term was made obsolete because it does not represent a function.					True				molecular_function											owl:Class	
GO:0052437	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont calcium ion flux	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont calcium ion flux|modulation by organism of defense-related symbiont Ca2+ flux				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0035831	biolink:NamedThing	palmatine biosynthetic process	The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants.	got7fsn_ti	palmatine formation|palmatine synthesis|palmatine biosynthesis|palmatine anabolism						bf	2011-05-04T03:06:06Z						biological_process											owl:Class	
GO:0034344	biolink:NamedThing	regulation of type III interferon production	Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	regulation of type III IFN production				Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.									biological_process											owl:Class	
GO:0009006	biolink:NamedThing	obsolete siroheme synthase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	sirohaem synthase activity|siroheme synthase activity				This term was made obsolete because it represents three different molecular functions.	GO:0043115|GO:0051266|GO:0019354|GO:0004851				True				molecular_function											owl:Class	
GO:0032308	biolink:NamedThing	positive regulation of prostaglandin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	got7fsn_ti	stimulation of prostaglandin secretion|upregulation of prostaglandin secretion|positive regulation of prostacyclin secretion|up regulation of prostaglandin secretion|up-regulation of prostaglandin secretion|activation of prostaglandin secretion													biological_process											owl:Class	
GO:0016963	biolink:NamedThing	obsolete alpha-2 macroglobulin receptor-associated protein activity	OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains.	got7fsn_ti	alpha-2 macroglobulin receptor-associated protein activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005102|GO:0005515				True				molecular_function											owl:Class	
GO:0034351	biolink:NamedThing	negative regulation of glial cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.	got7fsn_ti	negative regulation of glial cell apoptosis|down-regulation of glial cell apoptosis|downregulation of glial cell apoptosis|inhibition of glial cell apoptosis|down regulation of glial cell apoptosis													biological_process											owl:Class	
GO:1905489	biolink:NamedThing	regulation of sensory neuron axon guidance	Any process that modulates the frequency, rate or extent of sensory neuron axon guidance.	got7fsn_ti							hbye	2016-09-23T13:18:56Z						biological_process											owl:Class	
GO:0002837	biolink:NamedThing	regulation of immune response to tumor cell	Any process that modulates the frequency, rate, or extent of an immune response to tumor cell.	got7fsn_ti	regulation of immune response to tumour cell													biological_process											owl:Class	
GO:0043556	biolink:NamedThing	regulation of translation in response to oxidative stress	Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	got7fsn_ti														biological_process											owl:Class	
GO:1902158	biolink:NamedThing	positive regulation of response to G2 DNA damage checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.	got7fsn_ti	positive regulation of response to signal involved in G2/M transition DNA damage checkpoint|upregulation of G2/M transition DNA damage checkpoint effector process|up regulation of G2/M transition DNA damage checkpoint effector process|up-regulation of G2/M transition DNA damage checkpoint effector process|upregulation of response to G2 DNA damage checkpoint signaling|up regulation of response to signal involved in G2/M transition DNA damage checkpoint|up-regulation of response to G2 DNA damage checkpoint signaling|activation of G2/M transition DNA damage checkpoint effector process|up-regulation of response to signal involved in G2/M transition DNA damage checkpoint|activation of response to G2 DNA damage checkpoint signaling|upregulation of response to signal involved in G2/M transition DNA damage checkpoint|activation of response to signal involved in G2/M transition DNA damage checkpoint|up regulation of response to G2 DNA damage checkpoint signaling|positive regulation of G2/M transition DNA damage checkpoint effector process						jl	2013-05-21T15:45:10Z						biological_process											owl:Class	
GO:1903031	biolink:NamedThing	regulation of microtubule plus-end binding	Any process that modulates the frequency, rate or extent of microtubule plus-end binding.	got7fsn_ti							hjd	2014-05-16T18:38:26Z						biological_process											owl:Class	
GO:2000904	biolink:NamedThing	regulation of starch metabolic process	Any process that modulates the frequency, rate or extent of starch metabolic process.	got7fsn_ti	regulation of starch metabolism						tb	2011-07-28T11:33:13Z						biological_process											owl:Class	
GO:1901126	biolink:NamedThing	candicidin catabolic process	The chemical reactions and pathways resulting in the breakdown of candicidin.	got7fsn_ti	candicidin breakdown|candicidin degradation|candicidin catabolism						yaf	2012-07-11T03:16:54Z						biological_process											owl:Class	
CHEBI:57384	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015477	biolink:NamedThing	obsolete receptor porin activity	OBSOLETE. A porin of the bacterial outer membrane that forms transmembrane pores and transports relatively large molecules from the external milieu to the periplasm in an energized process. Energizing of transport across the outer membrane requires a heterotrimeric complex of proteins, the TonB-ExbB-ExbD complex, or in some cases, the TolA-TolQ-TolR complex. Energizing requires proton motive force across the cytoplasmic membrane.	got7fsn_ti	receptor porin activity				This term was made obsolete because it combines two functions that are not linked.					True				molecular_function											owl:Class	
GO:0015337	biolink:NamedThing	obsolete low affinity metal ion uptake transporter activity	OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Mn2+ or Cu2+.	got7fsn_ti	low affinity metal ion uptake transporter activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0015295|GO:0046873				True				molecular_function											owl:Class	
GO:1901072	biolink:NamedThing	glucosamine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines).	got7fsn_ti	glucosamines catabolic process|glucosamines breakdown|glucosamines degradation|glucosamine-containing compound catabolism|glucosamine-containing compound breakdown|glucosamines catabolism|glucosamine-containing compound degradation						bf	2012-07-02T03:18:25Z						biological_process											owl:Class	
GO:0000096	biolink:NamedThing	sulfur amino acid metabolic process	The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.	got7fsn_ti	sulphur amino acid metabolism|sulfur amino acid metabolism|sulphur amino acid metabolic process													biological_process											owl:Class	
GO:1900208	biolink:NamedThing	regulation of cardiolipin metabolic process	Any process that modulates the frequency, rate or extent of cardiolipin metabolic process.	got7fsn_ti	regulation of diphosphatidylglycerol metabolism|regulation of cardiolipin metabolism|regulation of diphosphatidylglycerol metabolic process						jl	2012-03-22T10:43:33Z						biological_process											owl:Class	
GO:0010641	biolink:NamedThing	positive regulation of platelet-derived growth factor receptor signaling pathway	Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.	got7fsn_ti	positive regulation of platelet-derived growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0033089	biolink:NamedThing	positive regulation of T cell differentiation in thymus	Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.	got7fsn_ti	positive regulation of thymocyte cell differentiation|positive regulation of T cell development in thymus|positive regulation of thymocyte differentiation|positive regulation of thymic T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0006804	biolink:NamedThing	obsolete peroxidase reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peroxidase reaction			GO:0004601	This term was made obsolete because it represents a molecular function.					True				biological_process											owl:Class	
CHEBI:61496	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046690	biolink:NamedThing	response to tellurium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.	got7fsn_ti	response to tellurium|tellurium sensitivity/resistance													biological_process											owl:Class	
GO:0046181	biolink:NamedThing	ketogluconate catabolic process	The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.	got7fsn_ti	ketogluconate degradation|ketogluconate breakdown|ketogluconate catabolism													biological_process											owl:Class	
GO:1901288	biolink:NamedThing	iron-sulfur-molybdenum cofactor biosynthetic process	The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor.	got7fsn_ti	iron-molybdenum cofactor anabolism|FeMo-co anabolism|FeMo-co biosynthetic process|iron-molybdenum cofactor biosynthetic process|iron-sulfur-molybdenum cofactor synthesis|iron-molybdenum cofactor biosynthesis|iron-molybdenum cofactor formation|FeMo-co biosynthesis|iron-sulfur-molybdenum cofactor biosynthesis|FeMo-co formation|FeMo-co synthesis|iron-sulfur-molybdenum cofactor formation|iron-molybdenum cofactor synthesis|iron-sulfur-molybdenum cofactor anabolism						yaf	2012-08-17T15:39:48Z						biological_process											owl:Class	
UBERON:0004148	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044056	biolink:NamedThing	modulation by symbiont of host digestive system process	The alteration by a symbiont organism of the functioning of a digestive system process, a physical, chemical, or biochemical process carried out by the host organism to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	got7fsn_ti	regulation by symbiont of host digestive system process													biological_process											owl:Class	
GO:0060125	biolink:NamedThing	negative regulation of growth hormone secretion	Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0006235	biolink:NamedThing	dTTP biosynthetic process	The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.	got7fsn_ti	dTTP biosynthesis|dTTP synthesis|dTTP formation|dTTP anabolism													biological_process											owl:Class	
GO:0034110	biolink:NamedThing	regulation of homotypic cell-cell adhesion	Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.	got7fsn_ti														biological_process											owl:Class	
GO:0047687	biolink:NamedThing	obsolete ascorbate 2,3-dioxygenase activity	OBSOLETE. Catalysis of the reaction: L-ascorbate + H(2)O + O(2) = L-threonate + 2 H(+) + oxalate.	got7fsn_ti	AAoxygenase activity|ascorbate 2,3-dioxygenase activity|ascorbate:oxygen 2,3-oxidoreductase (bond-cleaving)				This term was made obsolete because EC:1.13.11.13 was deleted; the activity is the sum of several enzymatic and spontaneous reactions.					True		KEGG_REACTION:R00646|MetaCyc:ASCORBATE-23-DIOXYGENASE-RXN|RHEA:21784		molecular_function											owl:Class	
GO:0055061	biolink:NamedThing	obsolete di-, tri-valent inorganic anion homeostasis	OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions within an organism or cell.	got7fsn_ti	di-, tri-valent inorganic anion homeostasis				This term was made obsolete because it has been split.	GO:0072506|GO:0072505				True				biological_process											owl:Class	
GO:0042593	biolink:NamedThing	glucose homeostasis	Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0120181	biolink:NamedThing	focal adhesion disassembly	The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity.	got7fsn_ti							krc	2018-07-12T17:37:14Z						biological_process											owl:Class	
GO:0016541	biolink:NamedThing	obsolete intein	OBSOLETE. Intervening protein sequence excised from a protein precursor in protein splicing; inteins catalyze their own excision and many also possess endonuclease activity.	got7fsn_ti	intein				This term was made obsolete because it refers to a protein sequence feature.	GO:0016539|GO:0004519				True				molecular_function											owl:Class	
GO:2000310	biolink:NamedThing	regulation of NMDA receptor activity	Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.	got7fsn_ti	regulation of N-methyl-D-aspartate selective glutamate receptor activity						bf	2011-01-18T10:06:37Z						biological_process											owl:Class	
CHEBI:50126	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35780	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901379	biolink:NamedThing	regulation of potassium ion transmembrane transport	Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.	got7fsn_ti	regulation of potassium ion membrane transport						rl	2012-09-28T15:58:00Z						biological_process											owl:Class	
GO:1902474	biolink:NamedThing	positive regulation of protein localization to synapse	Any process that activates or increases the frequency, rate or extent of protein localization to synapse.	got7fsn_ti	up regulation of protein localisation to synapse|up-regulation of protein localization to synapse|upregulation of protein localisation to synapse|upregulation of protein localization to synapse|activation of protein localisation to synapse|up-regulation of protein localisation to synapse|positive regulation of protein localisation to synapse|activation of protein localization to synapse|up regulation of protein localization to synapse						kmv	2013-10-25T15:09:18Z						biological_process											owl:Class	
GO:0060696	biolink:NamedThing	regulation of phospholipid catabolic process	Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.	got7fsn_ti							dph	2009-06-08T02:25:45Z						biological_process											owl:Class	
GO:0002585	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide antigen	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.	got7fsn_ti	up-regulation of antigen processing and presentation of peptide antigen|stimulation of antigen processing and presentation of peptide antigen|upregulation of antigen processing and presentation of peptide antigen|up regulation of antigen processing and presentation of peptide antigen|activation of antigen processing and presentation of peptide antigen|positive regulation of peptide antigen processing and presentation													biological_process											owl:Class	
GO:1904842	biolink:NamedThing	response to nitroglycerin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.	got7fsn_ti	response to nitroglycerine|response to nitroglycerol|response to trinitroglycerol|response to trinitroglycerin						sl	2015-12-07T18:30:47Z						biological_process											owl:Class	
GO:0032788	biolink:NamedThing	saturated monocarboxylic acid metabolic process	The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds.	got7fsn_ti	saturated monocarboxylic acid metabolism|saturated monocarboxylate metabolic process													biological_process											owl:Class	
GO:1900762	biolink:NamedThing	averantin catabolic process	The chemical reactions and pathways resulting in the breakdown of averantin.	got7fsn_ti	averantin degradation|averantin breakdown|averantin catabolism						di	2012-06-04T09:14:45Z						biological_process											owl:Class	
GO:0120028	biolink:NamedThing	negative regulation of osmosensory signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway.	got7fsn_ti							krc	2017-03-31T15:00:28Z						biological_process											owl:Class	
GO:0052500	biolink:NamedThing	obsolete positive regulation by organism of symbiont apoptosis	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of symbiont apoptotic programmed cell death|positive regulation by organism of symbiont apoptosis				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0014006	biolink:NamedThing	regulation of microglia differentiation	Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.	got7fsn_ti	regulation of microglial cell differentiation													biological_process											owl:Class	
GO:0015956	biolink:NamedThing	bis(5'-nucleosidyl) oligophosphate metabolic process	The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.	got7fsn_ti	bis(5'-nucleosidyl) oligophosphate metabolism													biological_process											owl:Class	
GO:1901540	biolink:NamedThing	ent-pimara-8(14),15-diene catabolic process	The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene.	got7fsn_ti	ent-pimara-8(14),15-diene catabolism|ent-pimara-8(14),15-diene degradation|ent-pimara-8(14),15-diene breakdown						di	2012-10-25T15:38:17Z						biological_process											owl:Class	
PO:0000262	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030828	biolink:NamedThing	obsolete positive regulation of cGMP biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.	got7fsn_ti	positive regulation of cGMP anabolism|up regulation of cGMP biosynthetic process|positive regulation of cGMP biosynthesis|positive regulation of cGMP formation|activation of cGMP biosynthetic process|stimulation of cGMP biosynthetic process|positive regulation of cGMP synthesis|upregulation of cGMP biosynthetic process|up-regulation of cGMP biosynthetic process				The reason for obsoletion is that this term represent the regulation of a signaling pathway,  not regulation of metabolism.	GO:0004383				True				biological_process											owl:Class	
GO:1904365	biolink:NamedThing	regulation of chemokinesis	Any process that modulates the frequency, rate or extent of chemokinesis.	got7fsn_ti							sl	2015-06-15T22:44:06Z						biological_process											owl:Class	
GO:1903394	biolink:NamedThing	protein localization to kinetochore involved in kinetochore assembly	Any protein localization to kinetochore that is involved in kinetochore assembly.	got7fsn_ti	protein localisation to kinetochore involved in centromere and kinetochore complex maturation|condensin localization to kinetochore involved in chromosome-kinetochore attachment|protein localization to kinetochore involved in kinetochore formation|protein localization to kinetochore involved in centromere/kinetochore complex maturation|condensin localization to kinetochore involved in kinetochore assembly|protein localisation to kinetochore involved in centromere/kinetochore complex maturation|protein localisation to kinetochore involved in chromosome-kinetochore attachment|protein localisation to kinetochore involved in kinetochore assembly|condensin localization to kinetochore involved in kinetochore formation|protein localisation to kinetochore involved in kinetochore formation|protein localization to kinetochore involved in centromere and kinetochore complex maturation|protein localization to kinetochore involved in chromosome-kinetochore attachment|condensin localization to kinetochore involved in centromere and kinetochore complex maturation|condensin localization to kinetochore involved in centromere/kinetochore complex maturation						vw	2014-08-29T13:11:55Z						biological_process											owl:Class	
CHEBI:16768	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000420	biolink:NamedThing	negative regulation of eosinophil extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation.	got7fsn_ti							mah	2011-02-23T01:47:18Z						biological_process											owl:Class	
GO:0045809	biolink:NamedThing	positive regulation of establishment of competence for transformation	Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation.	got7fsn_ti	activator of the establishment of competence for transformation activity|up regulation of establishment of competence for transformation|activation of establishment of competence for transformation|stimulation of establishment of competence for transformation|up-regulation of establishment of competence for transformation|upregulation of establishment of competence for transformation													biological_process											owl:Class	
GO:0015971	biolink:NamedThing	guanosine tetraphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.	got7fsn_ti	guanosine tetraphosphate (5'-ppGpp-3') catabolic process|guanosine tetraphosphate (5'-ppGpp-3') catabolism|guanosine tetraphosphate breakdown|guanosine tetraphosphate catabolism|guanosine tetraphosphate degradation													biological_process											owl:Class	
GO:0048310	biolink:NamedThing	obsolete nucleus inheritance	OBSOLETE. The partitioning of nuclei between daughter cells at cell division.	got7fsn_ti	cell nucleus inheritance				This term was obsoleted because it was not clearly defined.					True				biological_process											owl:Class	
GO:1900217	biolink:NamedThing	regulation of apoptotic process involved in metanephric nephron tubule development	Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.	got7fsn_ti	regulation of type I programmed cell death of metanephric nephron tubule development|regulation of apoptosis of metanephric nephron tubule development|regulation of apoptotic process of metanephric nephron tubule development|regulation of apoptotic cell death of metanephric nephron tubule development|regulation of apoptotic program of metanephric nephron tubule development|regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|regulation of programmed cell death by apoptosis of metanephric nephron tubule development|regulation of apoptotic programmed cell death of metanephric nephron tubule development						yaf	2012-03-22T10:53:51Z						biological_process											owl:Class	
GO:1902613	biolink:NamedThing	negative regulation of anti-Mullerian hormone signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.	got7fsn_ti	down regulation of anti-Mullerian hormone signaling pathway|downregulation of anti-Mullerian hormone signaling pathway|down-regulation of anti-Mullerian hormone signaling pathway|inhibition of anti-Mullerian hormone signaling pathway						hjd	2014-01-09T15:39:39Z						biological_process											owl:Class	
GO:1903486	biolink:NamedThing	establishment of mitotic actomyosin contractile ring localization	Any establishment of actomyosin contractile ring localization that is involved in mitotic cell cycle.	got7fsn_ti	establishment of actomyosin contractile ring localization involved in mitotic cell cycle						vw	2014-09-23T16:17:09Z						biological_process											owl:Class	
GO:1902174	biolink:NamedThing	positive regulation of keratinocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.	got7fsn_ti	activation of keratinocyte apoptosis|up regulation of keratinocyte apoptotic process|up regulation of keratinocyte apoptosis|up-regulation of keratinocyte apoptosis|positive regulation of keratinocyte apoptosis|upregulation of keratinocyte apoptotic process|upregulation of keratinocyte apoptosis|up-regulation of keratinocyte apoptotic process|activation of keratinocyte apoptotic process						rl	2013-05-29T14:36:21Z						biological_process											owl:Class	
GO:0030813	biolink:NamedThing	positive regulation of nucleotide catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.	got7fsn_ti	positive regulation of nucleotide breakdown|up regulation of nucleotide catabolic process|positive regulation of nucleotide catabolism|positive regulation of nucleotide degradation|upregulation of nucleotide catabolic process|stimulation of nucleotide catabolic process|activation of nucleotide catabolic process|up-regulation of nucleotide catabolic process													biological_process											owl:Class	
GO:0062065	biolink:NamedThing	box H/ACA snoRNP complex binding	Binding to a box H/ACA snoRNP complex.	got7fsn_ti							dph	2018-08-31T14:03:43Z						molecular_function											owl:Class	
GO:1905049	biolink:NamedThing	negative regulation of metallopeptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity.	got7fsn_ti	inhibition of metalloprotease activity|down-regulation of metalloprotease activity|down regulation of metalloprotease activity|negative regulation of metalloproteinase activity|downregulation of metalloproteinase activity|down-regulation of metallopeptidase activity|downregulation of metalloprotease activity|inhibition of metallopeptidase activity|inhibition of metalloproteinase activity|down regulation of metallopeptidase activity|negative regulation of metalloprotease activity|downregulation of metallopeptidase activity|down-regulation of metalloproteinase activity|down regulation of metalloproteinase activity						mm2	2016-03-15T16:44:37Z						biological_process											owl:Class	
GO:2000701	biolink:NamedThing	glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.	got7fsn_ti	glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|GDNF receptor signaling pathway of ureteric bud formation|glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation						yaf	2011-05-25T09:34:07Z						biological_process											owl:Class	
GO:0061942	biolink:NamedThing	negative regulation of c-di-GMP signaling	Any process that decreases the rate, frequency or extent of c-di-GMP signaling.	got7fsn_ti							dph	2017-09-14T19:13:44Z						biological_process											owl:Class	
GO:1901663	biolink:NamedThing	quinone biosynthetic process	The chemical reactions and pathways resulting in the formation of quinone.	got7fsn_ti	quinone synthesis|quinone cofactor biosynthesis|quinone formation|quinone cofactor biosynthetic process|quinone biosynthesis|quinone cofactor synthesis|quinone cofactor formation|quinone cofactor anabolism|quinone anabolism						pr	2012-11-20T14:44:48Z			GO:0045426			biological_process											owl:Class	
GO:0051247	biolink:NamedThing	positive regulation of protein metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.	got7fsn_ti	activation of protein metabolic process|up regulation of protein metabolic process|positive regulation of protein metabolism|up-regulation of protein metabolic process|upregulation of protein metabolic process|stimulation of protein metabolic process													biological_process											owl:Class	
GO:0052237	biolink:NamedThing	obsolete aerotaxis in other organism involved in symbiotic interaction	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	aerotaxis in other organism during symbiotic interaction|aerotaxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0046324	biolink:NamedThing	regulation of glucose import	Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.	got7fsn_ti	regulation of glucose uptake													biological_process											owl:Class	
GO:0034175	biolink:NamedThing	regulation of toll-like receptor 12 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 12 signalling pathway|regulation of TLR12 signaling pathway													biological_process											owl:Class	
GO:0033670	biolink:NamedThing	regulation of NAD+ kinase activity	Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.	got7fsn_ti	NAD kinase regulator|regulation of NAD kinase activity													biological_process											owl:Class	
GO:1901819	biolink:NamedThing	alpha-zeacarotene metabolic process	The chemical reactions and pathways involving alpha-zeacarotene.	got7fsn_ti	alpha-zeacarotene metabolism						yaf	2013-01-22T10:51:02Z						biological_process											owl:Class	
GO:0016265	biolink:NamedThing	obsolete death	OBSOLETE. A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.	got7fsn_ti					This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0008219|GO:0012501				True		Wikipedia:Death		biological_process											owl:Class	
GO:0000415	biolink:NamedThing	negative regulation of histone H3-K36 methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.	got7fsn_ti	inhibition of histone H3-K36 methylation|down regulation of histone H3-K36 methylation|down-regulation of histone H3-K36 methylation|downregulation of histone H3-K36 methylation													biological_process											owl:Class	
GO:0045195	biolink:NamedThing	obsolete gallstone formation	OBSOLETE. The formation of gallstones, hard, crystal-like accretions of cholesterol and bile pigments which develop when bile contains too much cholesterol and not enough bile.	got7fsn_ti	gallstone formation				This term was made obsolete because the process it represents is pathological.					True				biological_process											owl:Class	
GO:1902162	biolink:NamedThing	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.	got7fsn_ti							lb	2013-05-22T12:39:18Z						biological_process											owl:Class	
GO:0051871	biolink:NamedThing	dihydrofolic acid binding	Binding to dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms.	got7fsn_ti	dihydrofolate binding|DHF binding													molecular_function											owl:Class	
GO:1902974	biolink:NamedThing	meiotic DNA replication initiation	Any DNA replication initiation involved in meiotic cell cycle DNA replication.	got7fsn_ti	DNA replication initiation involved in meiotic cell cycle DNA replication|initiation of premeiotic DNA synthesis|initiation of meiotic DNA synthesis|premeiotic DNA replication initiation|meiotic DNA replication initiation|DNA replication initiation involved in meiotic DNA replication|initiation of premeiotic DNA replication						jl	2014-05-06T15:21:06Z			GO:0072691			biological_process											owl:Class	
GO:0016729	biolink:NamedThing	obsolete oxidoreductase activity, acting on CH2 groups, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD, NADP or oxygen.	got7fsn_ti	oxidoreductase activity, acting on CH2 groups, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016725				True				molecular_function											owl:Class	
GO:0048642	biolink:NamedThing	negative regulation of skeletal muscle tissue development	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.	got7fsn_ti	inhibition of skeletal muscle development|down-regulation of skeletal muscle development|down regulation of skeletal muscle development|downregulation of skeletal muscle development													biological_process											owl:Class	
GO:0045685	biolink:NamedThing	regulation of glial cell differentiation	Any process that modulates the frequency, rate or extent of glia cell differentiation.	got7fsn_ti	regulation of neuroglia differentiation|regulation of glia cell differentiation													biological_process											owl:Class	
GO:0052399	biolink:NamedThing	obsolete induction by organism of symbiont programmed cell death	OBSOLETE. The activation by an organism of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of symbiont programmed cell death|induction by organism of symbiont programmed cell death				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0016986	biolink:NamedThing	obsolete transcription initiation factor activity	OBSOLETE. Plays a role in regulating transcription initiation.	got7fsn_ti	transcription initiation factor activity|transcriptional initiation factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0140223				True				molecular_function											owl:Class	
GO:0140668	biolink:NamedThing	positive regulation of oxytocin production	Any process that activates or increases the frequency, rate or extent of production of oxytocin.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21535					pg	2021-06-24T11:31:26Z						biological_process											owl:Class	
GO:1900154	biolink:NamedThing	regulation of bone trabecula formation	Any process that modulates the frequency, rate or extent of bone trabecula formation.	got7fsn_ti	regulation of bone trabeculation|regulation of bone trabecula biogenesis|regulation of skeletal trabecula formation|regulation of skeletal trabeculation|regulation of skeletal trabecula biogenesis						vk	2012-03-07T01:47:03Z						biological_process											owl:Class	
GO:0033521	biolink:NamedThing	phytyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.	got7fsn_ti	phytyl diphosphate biosynthesis|phytyl diphosphate synthesis|phytyl diphosphate formation|phytyl diphosphate anabolism											MetaCyc:PWY-5063		biological_process											owl:Class	
GO:0052174	biolink:NamedThing	obsolete metabolism by symbiont of host macromolecule	OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0098739	biolink:NamedThing	import across plasma membrane	The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	uptake													biological_process											owl:Class	
GO:2000559	biolink:NamedThing	regulation of CD24 production	Any process that modulates the frequency, rate or extent of CD24 biosynthetic process.	got7fsn_ti	regulation of CD24 anabolism|regulation of CD24 biosynthesis|regulation of CD24 formation|regulation of CD24 biosynthetic process|regulation of CD24 synthesis						ebc	2011-04-03T08:56:56Z						biological_process											owl:Class	
GO:0009226	biolink:NamedThing	nucleotide-sugar biosynthetic process	The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti	nucleotide-sugar formation|nucleotide-sugar anabolism|nucleotide-sugar synthesis|nucleotide-sugar biosynthesis													biological_process											owl:Class	
GO:1902885	biolink:NamedThing	obsolete regulation of proteasome-activating ATPase activity	OBSOLETE. Any process that modulates the frequency, rate or extent of proteasome-activating ATPase activity.	got7fsn_ti	regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|regulation of proteasomal ATPase activity|regulation of proteasome channel opening activity|regulation of proteasome channel gating activity	https://github.com/geneontology/go-ontology/issues/20879			This term was obsoleted because it represents a molecular function.		di	2014-04-04T17:35:23Z		True				biological_process											owl:Class	
GO:0150139	biolink:NamedThing	positive regulation of interleukin-37 production	Any process that activates or increases the frequency, rate or extent of interleukin-37 production.	got7fsn_ti	positive regulation of interleukin-37 biosynthetic process						bc	2019-12-08T08:47:29Z						biological_process											owl:Class	
GO:0035928	biolink:NamedThing	rRNA import into mitochondrion	The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol into the mitochondrial matrix.	got7fsn_ti	cytoplasmic rRNA import into mitochondrion|nuclear-encoded rRNA import into mitochondrion						bf	2011-07-19T09:41:42Z						biological_process											owl:Class	
GO:1902896	biolink:NamedThing	terminal web assembly	The aggregation, arrangement and bonding together of a set of components to form a terminal web.	got7fsn_ti	terminal web formation						kmv	2014-04-08T15:15:25Z						biological_process											owl:Class	
GO:1990741	biolink:NamedThing	obsolete non-selective cation channel activity	OBSOLETE. Enables the non-selective, energy-independent passage of cations across a lipid bilayer down a concentration gradient.	got7fsn_ti	nonselective cation channel activity				This term was made obsolete because it was added in error.		pr	2015-05-11T13:27:15Z		True				molecular_function											owl:Class	
GO:0100020	biolink:NamedThing	obsolete regulation of transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0005323	biolink:NamedThing	obsolete very-low-density lipoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	VLDL|very-low-density lipoprotein			GO:0005319	This term was made obsolete because it does not represent a molecular function.					True				molecular_function											owl:Class	
CHEBI:61151	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001165	biolink:NamedThing	positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.	got7fsn_ti							se	2011-10-25T10:31:07Z						biological_process											owl:Class	
GO:0005625	biolink:NamedThing	obsolete soluble fraction	OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water.	got7fsn_ti	soluble|soluble fraction				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005575				True				cellular_component											owl:Class	
GO:0099602	biolink:NamedThing	neurotransmitter receptor regulator activity	A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.	got7fsn_ti														molecular_function											owl:Class	
GO:0050666	biolink:NamedThing	regulation of homocysteine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.	got7fsn_ti	regulation of Hcy metabolic process|regulation of homocysteine metabolism|regulation of Hcy metabolism													biological_process											owl:Class	
GO:0001152	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIC recruiting	OBSOLETE. The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the transcription factor TFIIIC to the promoter.	got7fsn_ti	RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIC recruiting transcription factor activity|TFIIIA activity|type 1 RNA polymerase III promoter recognition				This term was made obsolete in the 2018 Transcription branch revision. This represents the activity of TFIIIA only.		krc	2011-01-27T04:18:21Z		True				molecular_function											owl:Class	
CHEBI:28681	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120240	biolink:NamedThing	platelet glycocalyx	The carbohydrate rich layer at the outermost periphery of a platelet.	got7fsn_ti							krc	2020-07-27T22:44:42Z						cellular_component											owl:Class	
GO:0005569	biolink:NamedThing	obsolete small nucleolar RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	small nucleolar RNA				This term was made obsolete because it represents gene products.	GO:0030555				True				molecular_function											owl:Class	
GO:1901956	biolink:NamedThing	positive regulation of retrograde dense core granule transport	Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.	got7fsn_ti	up-regulation of retrograde dense core granule transport|upregulation of retrograde dense core granule transport|up regulation of retrograde dense core granule transport|activation of retrograde dense core granule transport						pr	2013-02-19T13:36:52Z						biological_process											owl:Class	
GO:1902816	biolink:NamedThing	regulation of protein localization to microtubule	Any process that modulates the frequency, rate or extent of protein localization to microtubule.	got7fsn_ti	regulation of protein localisation to microtubule						tb	2014-03-27T22:07:12Z						biological_process											owl:Class	
GO:2000387	biolink:NamedThing	regulation of antral ovarian follicle growth	Any process that modulates the frequency, rate or extent of antral ovarian follicle growth.	got7fsn_ti							yaf	2011-02-16T04:53:43Z						biological_process											owl:Class	
GO:2000807	biolink:NamedThing	regulation of synaptic vesicle clustering	Any process that modulates the frequency, rate or extent of synaptic vesicle clustering.	got7fsn_ti							pr	2011-07-06T09:50:30Z						biological_process											owl:Class	
GO:0061167	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010240	biolink:NamedThing	plastid pyruvate dehydrogenase complex	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria.	got7fsn_ti	dehydrogenase complex													cellular_component											owl:Class	
GO:1903125	biolink:NamedThing	negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation	A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity.	got7fsn_ti	negative regulation of TrxPx activity by peptidyl-threonine phosphorylation|negative regulation of TPx activity by peptidyl-threonine phosphorylation|negative regulation of thiol peroxidase activity by peptidyl-threonine phosphorylation						bf	2014-06-24T08:47:25Z						biological_process											owl:Class	
GO:0052172	biolink:NamedThing	obsolete metabolism by symbiont of host cell wall cellulose	OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0034884	biolink:NamedThing	obsolete gamma-N-formylaminovinylacetaldehyde dehydrogenase activity	OBSOLETE. Catalysis of the reaction: gamma-N-formylaminovinylacetaldehyde + H2O = gamma-N-formylaminovinylacetate + 2 H+ + 2 e-.	got7fsn_ti	gamma-N-formylaminovinylacetaldehyde dehydrogenase activity				This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.	GO:0016903				True				molecular_function											owl:Class	
GO:0075013	biolink:NamedThing	obsolete growth or development of symbiont on or near host phyllosphere	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of symbiont on or near host phyllosphere									True				biological_process											owl:Class	
GO:0071312	biolink:NamedThing	cellular response to alkaloid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.	got7fsn_ti							mah	2009-12-10T04:50:58Z						biological_process											owl:Class	
GO:0038069	biolink:NamedThing	obsolete MAP kinase phosphatase activity involved in regulation of cell wall biogenesis	OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to cell wall biogenesis.	got7fsn_ti	Slt2 phosphatase activity|Mpk1 phosphatase activity				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-25T03:38:58Z		True				molecular_function											owl:Class	
GO:1903641	biolink:NamedThing	positive regulation of gastrin-induced gastric acid secretion	Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion.	got7fsn_ti	upregulation of gastrin-induced gastric acid secretion|activation of gastrin-induced gastric acid secretion|up regulation of gastrin-induced gastric acid secretion|up-regulation of gastrin-induced gastric acid secretion						sl	2014-11-20T20:54:37Z						biological_process											owl:Class	
GO:1904601	biolink:NamedThing	protein localization to actin fusion focus	A process in which a protein is transported to, or maintained in, a location within an actin fusion focus.	got7fsn_ti	protein localisation to actin fusion focus|protein localization in actin fusion focus|protein localisation in actin fusion focus						al	2015-08-26T10:36:22Z						biological_process											owl:Class	
GO:1903402	biolink:NamedThing	regulation of renal phosphate excretion	Any process that modulates the frequency, rate or extent of renal phosphate excretion.	got7fsn_ti	regulation of renal phosphate ion excretion						pm	2014-09-01T13:47:01Z						biological_process											owl:Class	
GO:0005540	biolink:NamedThing	hyaluronic acid binding	Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.	got7fsn_ti	hyaluronan binding													molecular_function											owl:Class	
GO:0019214	biolink:NamedThing	obsolete surfactant activity	OBSOLETE. The action of reducing the surface tension of a liquid.	got7fsn_ti	surfactant activity				This term was made obsolete because it represents involvement in a process.	GO:0050828				True				molecular_function											owl:Class	
GO:1990919	biolink:NamedThing	proteasome-nuclear membrane anchor activity	The binding activity of a molecule that brings together a proteasome complex and a nuclear inner membrane, to maintain the nuclear membrane localization of the proteasome.	got7fsn_ti	nuclear membrane proteasome tether activity|nuclear membrane-proteasome tether activity|tethering factor for nuclear proteasome|nuclear membrane proteasome tether|nuclear membrane proteasome adaptor|nuclear membrane-proteasome anchor activity|nuclear membrane proteasome anchor	https://github.com/geneontology/go-ontology/issues/19119					vw	2015-12-14T14:01:45Z						molecular_function											owl:Class	
GO:0001314	biolink:NamedThing	obsolete replication of extrachromosomal circular DNA involved in replicative cell aging	OBSOLETE. Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.	got7fsn_ti	replication of extrachromosomal circular DNA during replicative cell aging|replication of extrachromosomal circular DNA during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0051580	biolink:NamedThing	regulation of neurotransmitter uptake	Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.	got7fsn_ti	regulation of neurotransmitter import|regulation of neurotransmitter reuptake													biological_process											owl:Class	
GO:0005351	biolink:NamedThing	carbohydrate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in).	got7fsn_ti	sugar porter activity|sugar transporter|cation/sugar symporter activity|hydrogen:sugar transporter activity|hydrogen:sugar symporter activity|sugar:hydrogen ion symporter activity|sugar efflux transmembrane transporter activity|sugar:proton symporter activity|proton:sugar symporter activity|lactose/glucose efflux transporter activity|sugar:hydrogen symporter activity										GO:0005403|GO:0015542	TC:2.A.1.1		molecular_function											owl:Class	
GO:1902956	biolink:NamedThing	regulation of mitochondrial electron transport, NADH to ubiquinone	Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.	got7fsn_ti	regulation of complex I (NADH to ubiquinone)|regulation of oxidative phosphorylation, NADH to ubiquinone						dph	2014-05-02T15:30:12Z						biological_process											owl:Class	
GO:0009474	biolink:NamedThing	obsolete nonaheme cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nonaheme cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0042315	biolink:NamedThing	obsolete cytosol nonspecific dipeptidase activity	OBSOLETE. Catalysis of the hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids.	got7fsn_ti	peptidase A activity|prolylglycine dipeptidase activity|N(2)-beta-alanylarginine dipeptidase activity|cytosol non-specific dipeptidase activity|human cytosolic non-specific dipeptidase activity|glycylleucine dipeptide hydrolase activity|glycyl-L-leucine dipeptidase activity|Pro-X dipeptidase activity|iminodipeptidase activity|glycylleucine hydrolase activity|glycyl-L-leucine hydrolase activity|glycyl-leucine dipeptidase activity|L-prolylglycine dipeptidase activity|prolyl dipeptidase activity|diglycinase activity|N2-beta-alanylarginine dipeptidase activity|glycyl-glycine dipeptidase activity|L-amino-acyl-L-amino-acid hydrolase activity|Gly-Leu hydrolase activity|glycylleucine peptidase activity|prolinase activity|cytosol nonspecific dipeptidase activity|glycyl-L-leucine peptidase activity|non-specific dipeptidase activity			GO:0016805	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1900183	biolink:NamedThing	regulation of xanthone-containing compound biosynthetic process	Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process.	got7fsn_ti	regulation of xanthone-containing compound synthesis|regulation of xanthone biosynthesis|regulation of xanthone biosynthetic process|regulation of xanthone-containing compound formation|regulation of xanthone-containing compound biosynthesis|regulation of xanthone-containing compound anabolism						di	2012-03-16T03:30:14Z						biological_process											owl:Class	
GO:1905397	biolink:NamedThing	activated CD8-positive, alpha-beta T cell apoptotic process	Any apoptotic process in an activated CD8-positive, alpha-beta T cell.	got7fsn_ti	activated CD8-positive, alpha-beta T-cell apoptotic process|activated CD8-positive, alpha-beta T lymphocyte apoptosis|activated CD8-positive, alpha-beta T-cell apoptosis|activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activated CD8-positive, alpha-beta T cell apoptosis|activated CD8-positive, alpha-beta T lymphocyte apoptotic process|activated CD8-positive, alpha-beta T-lymphocyte apoptosis						pga	2016-08-25T08:09:27Z						biological_process											owl:Class	
GO:0075169	biolink:NamedThing	obsolete positive regulation of symbiont protein kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
UBERON:0000934	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060850	biolink:NamedThing	obsolete regulation of transcription involved in cell fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0045165|GO:0006357	dph	2009-08-12T11:40:09Z		True				biological_process											owl:Class	
GO:0061397	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to copper ion	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0071280|GO:0045944	dph	2012-01-10T09:14:51Z		True				biological_process											owl:Class	
CL:0000021	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901730	biolink:NamedThing	monensin A biosynthetic process	The chemical reactions and pathways resulting in the formation of monensin A.	got7fsn_ti	monensin biosynthesis|monensin synthesis|monensin A synthesis|monensin A anabolism|monensin A formation|monensin A biosynthesis|monensin anabolism|monensin formation						yaf	2013-01-09T11:55:53Z						biological_process											owl:Class	
GO:0015560	biolink:NamedThing	obsolete L-idonate/D-gluconate:hydrogen symporter activity	OBSOLETE. Catalysis of the reaction: (L-idonate or D-gluconate)(out) + H+(out) = (L-iodonate or D-gluconate)(in) + H+(in).	got7fsn_ti	L-idonate/D-gluconate:proton symporter|L-idonate/D-gluconate:hydrogen symporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015568|GO:0015128|GO:0015295				True				molecular_function											owl:Class	
GO:0075051	biolink:NamedThing	obsolete negative regulation of symbiont cell wall strengthening involved in entry into host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont cell wall strengthening during entry into host				The reason for the obsoletion is that there is no evidence that those processes exist.					True				biological_process											owl:Class	
GO:0038006	biolink:NamedThing	netrin receptor activity involved in chemoattraction	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin.	got7fsn_ti	netrin receptor activity involved in positive chemotaxis|attractive netrin receptor activity						bf	2011-06-10T02:22:29Z						molecular_function											owl:Class	
GO:0001319	biolink:NamedThing	obsolete inheritance of oxidatively modified proteins involved in replicative cell aging	OBSOLETE. A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells.	got7fsn_ti	inheritance of oxidatively modified proteins during replicative cell aging|inheritance of oxidatively modified proteins during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0046229	biolink:NamedThing	obsolete 2-aminobenzenesulfonate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.	got7fsn_ti	2-aminobenzenesulfonate synthesis|2-aminobenzenesulfonate formation|2-aminobenzenesulfonate biosynthetic process|2-aminobenzenesulphonate biosynthetic process|2-aminobenzenesulfonate biosynthesis|2-aminobenzenesulphonate biosynthesis|2-aminobenzenesulfonate anabolism			GO:0018868	This term was made obsolete because 2-aminobenzenesulfonate is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0016564	biolink:NamedThing	obsolete transcription repressor activity	OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription.	got7fsn_ti	transcription repressor activity|negative transcriptional regulator activity|transcriptional repressor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001227				True				molecular_function											owl:Class	
GO:0015539	biolink:NamedThing	hexuronate:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.	got7fsn_ti	hexuronate porter activity|hexuronate (glucuronate/galacturonate) porter activity													molecular_function											owl:Class	
GO:1902350	biolink:NamedThing	cellular response to chloroquine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.	got7fsn_ti							kmv	2013-08-13T19:29:33Z						biological_process											owl:Class	
GO:0071398	biolink:NamedThing	cellular response to fatty acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.	got7fsn_ti							mah	2009-12-11T04:39:56Z						biological_process											owl:Class	
GO:0005490	biolink:NamedThing	obsolete cytochrome P450	OBSOLETE. A cytochrome b that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes:typically monooxygenases acting on lipophilic substrates.	got7fsn_ti	cytochrome P450				This term was made obsolete because its definition was changed and because it represents a gene product.					True				molecular_function											owl:Class	
GO:0086081	biolink:NamedThing	cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication	Binding to a protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells.	got7fsn_ti	cell adhesive protein binding involved in atrial cardiomyocyte-atrioventricular node cell communication|cell adhesive protein binding involved in atrial cardiomyocyte-AV node cell communication						dph	2011-11-22T11:00:47Z						molecular_function											owl:Class	
GO:1903158	biolink:NamedThing	obsolete L-glutamate transmembrane transporter activity involved in L-glutamate import into cell	OBSOLETE. Any L-glutamate transmembrane transporter activity that is involved in L-glutamate import into cell.	got7fsn_ti	L-glutamate transmembrane transporter activity involved in L-glutamate import into cell|glutamate/aspartate:sodium symporter activity involved in L-glutamate import into cell|glutamate/aspartate porter activity involved in L-glutamate import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:21Z		True				molecular_function											owl:Class	
GO:0044678	biolink:NamedThing	CoB-CoM heterodisulfide reductase complex	A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine.	got7fsn_ti	hydrogen:coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide oxidoreductase complex|coenzyme M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase complex						jl	2012-08-09T11:01:43Z						cellular_component											owl:Class	
GO:0071448	biolink:NamedThing	cellular response to alkyl hydroperoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.	got7fsn_ti							mah	2009-12-16T04:17:52Z						biological_process											owl:Class	
GO:1900637	biolink:NamedThing	regulation of asperfuranone biosynthetic process	Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process.	got7fsn_ti	regulation of asperfuranone formation|regulation of asperfuranone biosynthesis|regulation of asperfuranone synthesis|regulation of asperfuranone anabolism						di	2012-05-22T03:49:55Z						biological_process											owl:Class	
GO:1905777	biolink:NamedThing	regulation of exonuclease activity	Any process that modulates the frequency, rate or extent of exonuclease activity.	got7fsn_ti	regulation of exonuclease IX activity						nc	2016-12-21T21:32:07Z						biological_process											owl:Class	
GO:0010045	biolink:NamedThing	response to nickel cation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus.	got7fsn_ti	response to nickel													biological_process											owl:Class	
GO:0051158	biolink:NamedThing	L-arabitol catabolic process	The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.	got7fsn_ti	L-arabitol catabolism|L-arabitol degradation|L-arabitol breakdown													biological_process											owl:Class	
GO:0061148	biolink:NamedThing	extracellular matrix organization involved in endocardium development	A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	got7fsn_ti	extracellular matrix organisation involved in endocardium development						dph	2010-06-03T09:18:02Z						biological_process											owl:Class	
GO:0071589	biolink:NamedThing	pyridine nucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose.	got7fsn_ti	pyridine nucleoside formation|pyridine nucleoside anabolism|pyridine nucleoside biosynthesis|pyridine nucleoside synthesis						mah	2010-01-29T11:35:30Z						biological_process											owl:Class	
GO:1903873	biolink:NamedThing	negative regulation of DNA recombinase mediator complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly.	got7fsn_ti	downregulation of DNA recombinase mediator complex formation|down-regulation of DNA recombinase mediator complex formation|down regulation of DNA recombinase mediator complex formation|negative regulation of DNA recombinase mediator complex formation|down regulation of DNA recombinase mediator complex assembly|down-regulation of DNA recombinase mediator complex assembly|downregulation of DNA recombinase mediator complex assembly|inhibition of DNA recombinase mediator complex formation|inhibition of DNA recombinase mediator complex assembly						rb	2015-02-05T23:36:54Z						biological_process											owl:Class	
GO:0098520	biolink:NamedThing	excitatory neuromuscular junction	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction.	got7fsn_ti							dos	2013-10-14T12:02:51Z						cellular_component											owl:Class	
GO:0120179	biolink:NamedThing	adherens junction disassembly	The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	got7fsn_ti							krc	2018-07-12T17:29:56Z						biological_process											owl:Class	
GO:0033747	biolink:NamedThing	obsolete versatile peroxidase activity	OBSOLETE. Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O.	got7fsn_ti	hybrid peroxidase activity|reactive-black-5:hydrogen-peroxide oxidoreductase activity|polyvalent peroxidase activity|VP|versatile peroxidase activity			GO:0004601		GO:0052750				True				molecular_function											owl:Class	
GO:1900195	biolink:NamedThing	positive regulation of oocyte maturation	Any process that activates or increases the frequency, rate or extent of oocyte maturation.	got7fsn_ti	up-regulation of oocyte maturation|up regulation of oocyte maturation|activation of oocyte maturation|upregulation of oocyte maturation						kmv	2012-03-19T09:41:35Z						biological_process											owl:Class	
CHEBI:58540	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903087	biolink:NamedThing	mitotic spindle pole body duplication	Any spindle pole body duplication that is involved in the mitotic cell cycle.	got7fsn_ti	spindle pole body duplication associated with nuclear envelope involved in mitotic cell cycle|spindle pole body assembly involved in mitotic cell cycle|spindle pole body duplication in cytoplasm involved in mitotic cell cycle|spindle pole body biosynthesis involved in mitotic cell cycle|spindle pole body replication involved in mitotic cell cycle|spindle pole body duplication involved in mitotic cell cycle|spindle pole body formation involved in mitotic cell cycle|spindle pole body biogenesis involved in mitotic cell cycle						jl	2014-06-02T16:45:56Z						biological_process											owl:Class	
GO:1903784	biolink:NamedThing	positive regulation of sodium ion import across plasma membrane	Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane.	got7fsn_ti	upregulation of sodium ion import across plasma membrane|up-regulation of sodium ion import across plasma membrane|activation of sodium ion import across plasma membrane|up regulation of sodium ion import across plasma membrane						nc	2015-01-07T16:49:00Z						biological_process											owl:Class	
GO:0005177	biolink:NamedThing	obsolete neuroligin	OBSOLETE. A class of ligands for neurexins.	got7fsn_ti	neuroligin					GO:0042043				True				molecular_function											owl:Class	
GO:0099156	biolink:NamedThing	cell-cell signaling via exosome	Cell-cell signaling in which the ligand is carried between cells by an exosome.	got7fsn_ti	exosome mediated						dos	2017-07-05T16:40:45Z						biological_process											owl:Class	
CHEBI:57858	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62777	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902570	biolink:NamedThing	protein localization to nucleolus	A process in which a protein is transported to, or maintained in, a location within a nucleolus.	got7fsn_ti	protein localisation in nucleolus|protein localisation to nucleolus|protein localization in nucleolus						mah	2013-12-10T16:25:28Z						biological_process											owl:Class	
GO:0045305	biolink:NamedThing	obsolete regulator of establishment of competence for transformation activity	OBSOLETE. Functions to either promote or inhibit the establishment of competence for transformation.	got7fsn_ti	regulator of establishment of competence for transformation activity			GO:0045304	This term was made obsolete because it does not represent a true function.					True				molecular_function											owl:Class	
GO:1904476	biolink:NamedThing	negative regulation of small GTPase binding	Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase binding.	got7fsn_ti	negative regulation of Ras GTPase binding|inhibition of small GTPase binding|downregulation of small GTPase binding|down-regulation of Ras GTPase binding|down regulation of small GTPase binding	https://github.com/geneontology/go-ontology/issues/18750					sl	2015-07-10T22:47:38Z						biological_process											owl:Class	
GO:1902036	biolink:NamedThing	regulation of hematopoietic stem cell differentiation	Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.	got7fsn_ti	regulation of hemopoietic stem cell differentiation|regulation of haematopoietic stem cell differentiation|regulation of haemopoietic stem cell differentiation						ss	2013-04-02T05:19:09Z						biological_process											owl:Class	
GO:2001228	biolink:NamedThing	regulation of response to gamma radiation	Any process that modulates the frequency, rate or extent of response to gamma radiation.	got7fsn_ti	regulation of response to gamma-ray photon|regulation of response to gamma ray						yaf	2011-11-20T04:51:07Z						biological_process											owl:Class	
GO:0034240	biolink:NamedThing	negative regulation of macrophage fusion	Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion.	got7fsn_ti														biological_process											owl:Class	
GO:2001009	biolink:NamedThing	regulation of plant-type cell wall cellulose biosynthetic process	Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.	got7fsn_ti	regulation of cell wall cellulose biosynthesis|regulation of cellulose biosynthesis during cell wall biosynthesis						tt	2011-08-08T08:47:15Z						biological_process											owl:Class	
GO:1905869	biolink:NamedThing	negative regulation of 3'-UTR-mediated mRNA stabilization	Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.	got7fsn_ti	downregulation of 3'-UTR-mediated mRNA stabilization|negative regulation of 3'-untranslated region-mediated mRNA stabilization|inhibition of 3'-untranslated region-mediated mRNA stabilization|inhibition of 3'-UTR-mediated mRNA stabilization|down-regulation of 3'-UTR-mediated mRNA stabilization|down-regulation of 3'-untranslated region-mediated mRNA stabilization|down regulation of 3'-UTR-mediated mRNA stabilization|downregulation of 3'-untranslated region-mediated mRNA stabilization|down regulation of 3'-untranslated region-mediated mRNA stabilization						rz	2017-01-27T11:51:46Z						biological_process											owl:Class	
GO:0036208	biolink:NamedThing	obsolete negative regulation of histone gene expression	OBSOLETE. Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.	got7fsn_ti	downregulation of histone gene expression|down-regulation of histone gene expression|negative regulation of expression of histone-encoding gene|inhibition of histone gene expression	https://github.com/geneontology/go-ontology/issues/20209			This term was obsoleted because the gene product should be captured as an annotation extension using 'has input'.	GO:0000122	bf	2012-04-25T09:29:43Z		True				biological_process											owl:Class	
GO:0006017	biolink:NamedThing	deoxyribose 1,5-bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.	got7fsn_ti	deoxyribose 1,5-bisphosphate biosynthesis|deoxyribose 1,5-bisphosphate formation|deoxyribose 1,5-bisphosphate anabolism|deoxyribose 1,5-bisphosphate synthesis													biological_process											owl:Class	
GO:0071317	biolink:NamedThing	cellular response to isoquinoline alkaloid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.	got7fsn_ti							mah	2009-12-10T05:06:08Z						biological_process											owl:Class	
GO:0060398	biolink:NamedThing	regulation of growth hormone receptor signaling pathway	Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.	got7fsn_ti	regulation of growth hormone receptor signalling pathway													biological_process											owl:Class	
GO:0071523	biolink:NamedThing	obsolete TIR domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TIR domain interaction.	got7fsn_ti					This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-07T02:11:47Z		True				biological_process											owl:Class	
UBERON:0002202	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019347	biolink:NamedThing	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol synthesis|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol formation|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthesis|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol anabolism											MetaCyc:MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS		biological_process											owl:Class	
UBERON:0004363	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27365	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061086	biolink:NamedThing	negative regulation of histone H3-K27 methylation	Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.	got7fsn_ti							dph	2010-04-26T01:23:52Z						biological_process											owl:Class	
GO:1905706	biolink:NamedThing	regulation of mitochondrial ATP synthesis coupled proton transport	Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.	got7fsn_ti							vw	2016-11-17T14:07:33Z						biological_process											owl:Class	
GO:0050758	biolink:NamedThing	regulation of thymidylate synthase biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.	got7fsn_ti	regulation of thymidylate synthase biosynthesis|regulation of thymidylate synthase synthesis|regulation of thymidylate synthase formation|regulation of thymidylate synthase anabolism													biological_process											owl:Class	
GO:0004214	biolink:NamedThing	obsolete dipeptidyl-peptidase I activity	OBSOLETE. Catalysis of the release of an N-terminal dipeptide, Xaa-Xbb from Xaa-Xbb-Xcc, except when Xaa is Arg or Lys, or Xbb or Xcc is Pro.	got7fsn_ti	dipeptidyl aminopeptidase I activity|dipeptide arylamidase I|cathepsin J activity|dipeptidyl transferase activity|cathepsin C activity|DAP I|dipeptidyl-peptidase I activity				This term was made obsolete because it represents a gene product.	GO:0008234|GO:0008239				True		EC:3.4.14.1|MetaCyc:3.4.14.1-RXN		molecular_function											owl:Class	
GO:0070511	biolink:NamedThing	negative regulation of histone H4-K20 methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.	got7fsn_ti	down regulation of histone H4-K20 methylation|down-regulation of histone H4-K20 methylation|downregulation of histone H4-K20 methylation|inhibition of histone H4-K20 methylation													biological_process											owl:Class	
GO:1901898	biolink:NamedThing	negative regulation of relaxation of cardiac muscle	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle.	got7fsn_ti	inhibition of relaxation of cardiac muscle|down-regulation of relaxation of cardiac muscle|downregulation of relaxation of cardiac muscle|down regulation of relaxation of cardiac muscle						rl	2013-02-06T21:27:02Z						biological_process											owl:Class	
GO:0030022	biolink:NamedThing	obsolete adhesive extracellular matrix constituent	OBSOLETE. A constituent of the extracellular matrix that facilitates attachment of cells to the matrix.	got7fsn_ti	adhesive extracellular matrix constituent				This term was made obsolete because it does not represent a molecular function.	GO:0030674|GO:0031012|GO:0050840|GO:0050839				True				molecular_function											owl:Class	
GO:0097717	biolink:NamedThing	copper ion transport across blood-cerebrospinal fluid barrier	The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier.	got7fsn_ti	copper ion transport across BCSFB|copper ion transport across blood/cerebrospinal fluid barrier|copper ion transport across BCB|copper ion transport across blood/CSF barrier|copper ion transport across blood-CSF barrier						pr	2016-08-23T14:37:33Z						biological_process											owl:Class	
GO:0060765	biolink:NamedThing	regulation of androgen receptor signaling pathway	Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.	got7fsn_ti	regulation of androgen receptor signalling pathway						dph	2009-07-06T11:07:38Z						biological_process											owl:Class	
GO:0034156	biolink:NamedThing	negative regulation of toll-like receptor 7 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 7 signalling pathway|negative regulation of TLR7 signaling pathway													biological_process											owl:Class	
PR:000003113	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015366	biolink:NamedThing	malate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in).	got7fsn_ti	malate permease|L-malic acid permease|malate:hydrogen symporter activity|L-malic acid:proton symporter activity													molecular_function											owl:Class	
GO:0046091	biolink:NamedThing	deoxyadenosine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.	got7fsn_ti	deoxyadenosine formation|deoxyadenosine biosynthesis|deoxyadenosine anabolism|deoxyadenosine synthesis													biological_process											owl:Class	
GO:2000029	biolink:NamedThing	regulation of proanthocyanidin biosynthetic process	Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.	got7fsn_ti	regulation of proanthocyanidin anabolism|regulation of proanthocyanidin biosynthesis|regulation of proanthocyanidin synthesis|regulation of proanthocyanidin formation						tb	2010-08-05T11:28:08Z						biological_process											owl:Class	
GO:1902970	biolink:NamedThing	premeiotic DNA replication DNA duplex unwinding	Any DNA duplex unwinding involved in meiotic cell cycle DNA replication.	got7fsn_ti	DNA duplex unwinding involved in meiotic cell cycle DNA replication|DNA duplex unwinding involved in meiotic DNA replication						jl	2014-05-06T15:20:41Z						biological_process											owl:Class	
GO:2000865	biolink:NamedThing	negative regulation of estradiol secretion	Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion.	got7fsn_ti	negative regulation of oestradiol secretion						bf	2011-07-26T08:49:17Z						biological_process											owl:Class	
GO:0000314	biolink:NamedThing	organellar small ribosomal subunit	The smaller of the two subunits of an organellar ribosome.	got7fsn_ti														cellular_component											owl:Class	
GO:0034763	biolink:NamedThing	negative regulation of transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.	got7fsn_ti	down regulation of transmembrane transport|downregulation of transmembrane transport|negative regulation of membrane transport|down-regulation of transmembrane transport|inhibition of transmembrane transport													biological_process											owl:Class	
GO:1902679	biolink:NamedThing	negative regulation of RNA biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.	got7fsn_ti	inhibition of RNA biosynthesis|downregulation of RNA synthesis|negative regulation of RNA anabolism|down regulation of RNA synthesis|negative regulation of RNA synthesis|inhibition of RNA synthesis|down-regulation of RNA biosynthesis|down regulation of RNA formation|inhibition of RNA biosynthetic process|down regulation of RNA biosynthesis|down-regulation of RNA biosynthetic process|down regulation of RNA biosynthetic process|down-regulation of RNA formation|downregulation of RNA anabolism|downregulation of RNA biosynthetic process|down-regulation of RNA synthesis|downregulation of RNA formation|inhibition of RNA formation|down-regulation of RNA anabolism|down regulation of RNA anabolism|negative regulation of RNA biosynthesis|inhibition of RNA anabolism|negative regulation of RNA formation|downregulation of RNA biosynthesis						jl	2014-02-05T16:32:01Z						biological_process											owl:Class	
GO:0120062	biolink:NamedThing	positive regulation of gastric emptying	Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.	got7fsn_ti							krc	2017-06-13T21:55:08Z						biological_process											owl:Class	
GO:0052375	biolink:NamedThing	obsolete evasion or tolerance by organism of symbiont-produced nitric oxide	OBSOLETE. The process by which an organism avoids the effects of nitric oxide produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	evasion or tolerance of NO produced by symbiont in response to organism|evasion or tolerance by organism of symbiont-produced nitric oxide|evasion or tolerance by organism of symbiont nitric oxide|evasion or tolerance of nitric oxide produced by symbiont in response to organism|evasion or tolerance by organism of symbiont NO|evasion or tolerance by organism of symbiont-produced NO				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0075151	biolink:NamedThing	obsolete positive regulation of receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont receptor-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
CL:0000595	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034126	biolink:NamedThing	positive regulation of MyD88-dependent toll-like receptor signaling pathway	Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.	got7fsn_ti	positive regulation of MyD88-dependent toll-like receptor signalling pathway|positive regulation of MyD88-dependent TLR signaling pathway													biological_process											owl:Class	
GO:0035464	biolink:NamedThing	regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry	Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves.	got7fsn_ti	regulation of TGFbeta receptor signaling pathway involved in determination of left/right asymmetry|regulation of TGF-beta receptor signalling pathway involved in determination of left/right asymmetry|regulation of TGF-beta receptor signaling pathway involved in determination of left/right asymmetry|regulation of transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry|regulation of TGFbeta receptor signalling pathway involved in determination of left/right asymmetry						bf	2010-04-19T01:31:56Z						biological_process											owl:Class	
GO:0015506	biolink:NamedThing	nucleoside:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in).	got7fsn_ti	nucleoside:hydrogen ion symporter activity|nucleoside permease activity|nucleoside:hydrogen symporter activity										GO:0015536			molecular_function											owl:Class	
GO:0034509	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905558	biolink:NamedThing	negative regulation of mitotic nuclear envelope disassembly	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.	got7fsn_ti	negative regulation of mitotic nuclear envelope breakdown|downregulation of mitotic nuclear envelope breakdown|downregulation of mitotic nuclear envelope catabolism|down regulation of mitotic nuclear envelope breakdown|inhibition of mitotic nuclear envelope breakdown|downregulation of mitotic nuclear envelope degradation|downregulation of mitotic nuclear envelope disassembly|negative regulation of mitotic nuclear envelope degradation|inhibition of mitotic nuclear envelope disassembly|negative regulation of mitotic nuclear envelope catabolism|down-regulation of mitotic nuclear envelope breakdown|down regulation of mitotic nuclear envelope degradation|inhibition of mitotic nuclear envelope degradation|down-regulation of mitotic nuclear envelope disassembly|inhibition of mitotic nuclear envelope catabolism|down-regulation of mitotic nuclear envelope degradation|down regulation of mitotic nuclear envelope catabolism|down-regulation of mitotic nuclear envelope catabolism|down regulation of mitotic nuclear envelope disassembly						hbye	2016-10-14T13:15:08Z						biological_process											owl:Class	
GO:1902114	biolink:NamedThing	D-valine metabolic process	The chemical reactions and pathways involving D-valine.	got7fsn_ti	D-valine metabolism						al	2013-05-13T23:27:23Z						biological_process											owl:Class	
GO:0006845	biolink:NamedThing	obsolete mitochondrial aspartate/glutamate transport	OBSOLETE. The directed movement of aspartate and glutamate into, out of or within a mitochondrion.	got7fsn_ti	mitochondrial aspartate/glutamate transport				This term was made obsolete because it represents a function rather than a process.	GO:0015813|GO:0015810|GO:0006839				True				biological_process											owl:Class	
GO:0004243	biolink:NamedThing	obsolete mitochondrial intermediate peptidase activity	OBSOLETE. Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion.	got7fsn_ti	mitochondrial intermediate peptidase activity|MIP|mitochondrial intermediate precursor-processing proteinase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0018955	biolink:NamedThing	phenanthrene metabolic process	The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish.	got7fsn_ti	phenanthrene metabolism											UM-BBD_pathwayID:pha		biological_process											owl:Class	
GO:0033220	biolink:NamedThing	obsolete ATPase-coupled amide-transporter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + amide(out) = ADP + phosphate + amide(in).	got7fsn_ti	ATP-dependent amide-transporter activity|amide-transporting ATPase activity				This term was obsoleted because it is an unnecessary grouping class.					True				molecular_function											owl:Class	
GO:0120007	biolink:NamedThing	negative regulation of glutamatergic neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13107					krc	2017-03-01T16:25:50Z						biological_process											owl:Class	
GO:1904644	biolink:NamedThing	cellular response to curcumin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.	got7fsn_ti							sl	2015-08-31T20:38:17Z						biological_process											owl:Class	
GO:0015096	biolink:NamedThing	obsolete manganese resistance permease activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	manganese resistance permease activity				This term was made obsolete because the term is undefined and we don't know the mechanism so we can't make a correct definition.					True				molecular_function											owl:Class	
GO:0006203	biolink:NamedThing	dGTP catabolic process	The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.	got7fsn_ti	dGTP catabolism|dGTP breakdown|dGTP degradation													biological_process											owl:Class	
GO:0051143	biolink:NamedThing	propanediol metabolic process	The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.	got7fsn_ti	propylene glycol metabolism|propylene glycol metabolic process|1,2-dihydroxypropane metabolic process|propanediol metabolism|1,2-dihydroxypropane metabolism													biological_process											owl:Class	
GO:1905333	biolink:NamedThing	regulation of gastric motility	Any process that modulates the frequency, rate or extent of gastric motility.	got7fsn_ti							als	2016-07-22T09:47:31Z						biological_process											owl:Class	
GO:1904035	biolink:NamedThing	regulation of epithelial cell apoptotic process	Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process.	got7fsn_ti	regulation of epithelial cell apoptosis|regulation of epitheliocyte apoptosis|regulation of epitheliocyte apoptotic process						sl	2015-03-13T22:05:41Z						biological_process											owl:Class	
GO:1904669	biolink:NamedThing	ATP export	The directed movement of ATP out of a cell or organelle.	got7fsn_ti	ATP efflux						tb	2015-09-09T16:33:06Z						biological_process											owl:Class	
GO:1900842	biolink:NamedThing	positive regulation of helvolic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process.	got7fsn_ti	up regulation of helvolic acid biosynthetic process|up-regulation of helvolic acid biosynthetic process|upregulation of helvolic acid biosynthetic process						di	2012-06-07T09:39:05Z						biological_process											owl:Class	
GO:0005799	biolink:NamedThing	obsolete coatomer	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	COPI vesicle|coatomer				This term was made obsolete because its position and synonym implied that it confused a coated vesicle with the coat itself.	GO:0030126|GO:0030137				True				cellular_component											owl:Class	
GO:1905632	biolink:NamedThing	protein localization to euchromatin	A process in which a protein is transported to, or maintained in, a location within an euchromatin.	got7fsn_ti	protein localisation to euchromatin|protein localisation in euchromatin|protein localization in euchromatin						pga	2016-11-01T16:16:14Z						biological_process											owl:Class	
GO:0033530	biolink:NamedThing	raffinose metabolic process	The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	raffinose metabolism													biological_process											owl:Class	
GO:1903330	biolink:NamedThing	negative regulation of iron-sulfur cluster assembly	Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly.	got7fsn_ti	down regulation of iron-sulphur cluster assembly|negative regulation of iron-sulfur cluster biosynthesis|down regulation of iron-sulfur cluster biosynthesis|inhibition of iron-sulfur cluster assembly|down-regulation of iron-sulfur cluster biosynthesis|downregulation of iron-sulphur cluster assembly|inhibition of iron-sulphur cluster assembly|inhibition of iron-sulfur cluster biosynthesis|downregulation of iron-sulfur cluster biosynthesis|down-regulation of iron-sulfur cluster assembly|down-regulation of iron-sulphur cluster assembly|down regulation of iron-sulfur cluster assembly|negative regulation of iron-sulphur cluster assembly|downregulation of iron-sulfur cluster assembly						vw	2014-08-18T13:12:50Z						biological_process											owl:Class	
GO:2000486	biolink:NamedThing	negative regulation of glutamine transport	Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport.	got7fsn_ti	negative regulation of L-glutamine transport						bf	2011-03-11T09:33:07Z						biological_process											owl:Class	
GO:0051860	biolink:NamedThing	obsolete evasion or tolerance of symbiont defenses	OBSOLETE. The process, either active or passive, by which an organism evades or tolerates the effects of the defense(s) or defense molecules of a symbiont organism. Symbiont defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14862			This term was made obsolete because it is not relevant for the host in a host-symbiont interaction.					True				biological_process											owl:Class	
GO:0015624	biolink:NamedThing	ABC-type ferric-enterobactin transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).	got7fsn_ti	ferric-enterobactin porter activity|ferric-enterobactin-transporting ATPase activity|ATP-dependent ferric-enterobactin transmembrane transporter activity|ATPase-coupled ferric-enterobactin transmembrane transporter activity|ferric-enterobactin ABC transporter											EC:7.2.2.17|MetaCyc:ABC-10-RXN|RHEA:58492		molecular_function											owl:Class	
GO:0090237	biolink:NamedThing	regulation of arachidonic acid secretion	Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.	got7fsn_ti							tb	2010-01-20T03:32:22Z						biological_process											owl:Class	
GO:0106138	biolink:NamedThing	Sec61 translocon complex binding	Binding to a Sec61 translocon complex.	got7fsn_ti							hjd	2018-08-15T14:50:29Z						molecular_function											owl:Class	
GO:1900822	biolink:NamedThing	regulation of ergot alkaloid biosynthetic process	Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process.	got7fsn_ti	regulation of ergot alkaloid biosynthesis|regulation of ergot alkaloid synthesis|regulation of ergot alkaloid formation|regulation of ergot alkaloid anabolism						di	2012-06-04T11:12:32Z						biological_process											owl:Class	
GO:1901192	biolink:NamedThing	positive regulation of formation of translation initiation ternary complex	Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.	got7fsn_ti	positive regulation of translation initiation ternary complex assembly|upregulation of translation initiation ternary complex assembly|upregulation of formation of translation initiation ternary complex|activation of formation of translation initiation ternary complex|up regulation of translation initiation ternary complex assembly|up-regulation of formation of translation initiation ternary complex|up regulation of formation of translation initiation ternary complex|activation of translation initiation ternary complex assembly|up-regulation of translation initiation ternary complex assembly						ss	2012-07-25T02:27:29Z						biological_process											owl:Class	
GO:0001812	biolink:NamedThing	positive regulation of type I hypersensitivity	Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response.	got7fsn_ti	up regulation of type I hypersensitivity|up-regulation of type I hypersensitivity|stimulation of type I hypersensitivity|upregulation of type I hypersensitivity|activation of type I hypersensitivity													biological_process											owl:Class	
GO:0034172	biolink:NamedThing	negative regulation of toll-like receptor 11 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 11 signalling pathway|negative regulation of TLR11 signaling pathway													biological_process											owl:Class	
GO:1902866	biolink:NamedThing	regulation of retina development in camera-type eye	Any process that modulates the frequency, rate or extent of retina development in camera-type eye.	got7fsn_ti	regulation of retinal development|regulation of retina development in camera-style eye						mr	2014-04-03T15:24:17Z						biological_process											owl:Class	
GO:1900140	biolink:NamedThing	regulation of seedling development	Any process that modulates the frequency, rate or extent of seedling development.	got7fsn_ti							dhl	2012-03-01T09:26:07Z						biological_process											owl:Class	
GO:1902786	biolink:NamedThing	response to dodecane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.	got7fsn_ti							tt	2014-03-21T13:41:36Z						biological_process											owl:Class	
GO:0061883	biolink:NamedThing	clathrin-dependent endocytosis involved in vitellogenesis	A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition.	got7fsn_ti	clathrin-dependent endocytosis involved in yolk formation						dph	2017-05-30T14:41:21Z						biological_process											owl:Class	
GO:1904809	biolink:NamedThing	regulation of dense core granule transport	Any process that modulates the frequency, rate or extent of dense core granule transport.	got7fsn_ti	regulation of dense core vesicle transport				cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).		es	2015-11-11T10:40:10Z						biological_process											owl:Class	
CHEBI:26346	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904753	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.	got7fsn_ti	downregulation of vascular smooth muscle cell migration|down-regulation of vascular associated smooth muscle cell migration|inhibition of vascular associated smooth muscle cell migration|downregulation of vascular associated smooth muscle cell migration|down regulation of vascular smooth muscle cell migration|down-regulation of vascular smooth muscle cell migration|down regulation of vascular associated smooth muscle cell migration|inhibition of vascular smooth muscle cell migration|negative regulation of vascular smooth muscle cell migration						rph	2015-10-19T15:49:58Z						biological_process											owl:Class	
GO:0007246	biolink:NamedThing	obsolete activation of MAPKK (mating sensu Saccharomyces)	OBSOLETE. Upregulation of a MAP kinase kinase in the context of transduction of mating pheromone signal, as described for Saccharomyces.	got7fsn_ti	activation of MAPKK (mating sensu Saccharomyces)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0039578	biolink:NamedThing	obsolete suppression by virus of host JAK1 activity via JAK1 binding	OBSOLETE.  Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by interacting directly and selectively with JAK1. For example, the polyoma virus T antigen binds to JAK1 and renders it inactive.	got7fsn_ti					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True				biological_process											owl:Class	
GO:1902859	biolink:NamedThing	propionyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of propionyl-CoA.	got7fsn_ti	propionyl-CoA degradation|propionyl-CoA breakdown|propionyl-CoA catabolism						tt	2014-04-03T03:10:23Z						biological_process											owl:Class	
GO:0061973	biolink:NamedThing	membrane bone morphogenesis	The process in which bone which forms deep in the organism are generated and organized.	got7fsn_ti							dph	2018-02-12T18:21:09Z						biological_process											owl:Class	
GO:1904680	biolink:NamedThing	peptide transmembrane transporter activity	Enables the transfer of a peptide from one side of a membrane to the other.	got7fsn_ti	peptide uptake permease activity|peptide transporter activity						tb	2015-09-22T18:50:41Z			GO:0015637|GO:0015197	Reactome:R-HSA-1500817		molecular_function											owl:Class	
GO:0071334	biolink:NamedThing	cellular response to rhamnose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.	got7fsn_ti	cellular response to L-rhamnose stimulus						mah	2009-12-10T05:38:38Z						biological_process											owl:Class	
GO:1903359	biolink:NamedThing	lateral cortical node assembly	The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node.	got7fsn_ti	lateral cortical node formation|Skb1-containing cortical node assembly|Skb1-containing cortical node formation						mah	2014-08-21T10:22:51Z						biological_process											owl:Class	
GO:0000197	biolink:NamedThing	obsolete activation of MAPKKK activity involved in cell wall organization or biogenesis	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of cell wall organization or biogenesis.	got7fsn_ti	activation of MAPKKK activity involved in cell wall integrity|activation of MAPKKK activity involved in cell wall biogenesis|activation of MAP kinase kinase kinase activity during cell wall biogenesis|cell wall biogenesis, activation of MAP kinase kinase kinase activity|cell wall biogenesis, activation of MAPKKK activity	https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.	GO:0000165|GO:0043539				True				biological_process											owl:Class	
GO:0051176	biolink:NamedThing	positive regulation of sulfur metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.	got7fsn_ti	upregulation of sulfur metabolic process|stimulation of sulfur metabolic process|positive regulation of sulfur metabolism|activation of sulfur metabolic process|up regulation of sulfur metabolic process|up-regulation of sulfur metabolic process|positive regulation of sulphur metabolism|positive regulation of sulphur metabolic process													biological_process											owl:Class	
GO:1904912	biolink:NamedThing	positive regulation of establishment of RNA localization to telomere	Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere.	got7fsn_ti	upregulation of establishment of RNA localization to telomere|upregulation of establishment of RNA localisation to telomere|up regulation of establishment of RNA localisation to telomere|up-regulation of establishment of RNA localisation to telomere|up regulation of establishment of RNA localization to telomere|activation of establishment of RNA localization to telomere|activation of establishment of RNA localisation to telomere|up-regulation of establishment of RNA localization to telomere|positive regulation of establishment of RNA localisation to telomere						rph	2016-01-19T10:34:35Z						biological_process											owl:Class	
GO:0120288	biolink:NamedThing	negative regulation of aspartic endopeptidase activity, intramembrane cleaving	Any process that decreases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20341					krc	2020-11-19T22:23:52Z						biological_process											owl:Class	
GO:0052341	biolink:NamedThing	obsolete catabolism by organism of cell wall pectin in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism by organism of cell wall pectin in other organism during symbiotic interaction				This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0031445	biolink:NamedThing	regulation of heterochromatin assembly	Any process that modulates the frequency, rate, extent or location of heterochromatin formation.	got7fsn_ti	regulation of heterochromatin formation													biological_process											owl:Class	
GO:0001170	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase I enhancer sequence-specific binding	OBSOLETE. Binding to a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I.	got7fsn_ti	RNA polymerase I enhancer sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/15787			This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2011-02-03T04:10:59Z		True				molecular_function											owl:Class	
GO:0005696	biolink:NamedThing	obsolete telomere	OBSOLETE. A complex of DNA and protein that seals the end of a chromosome. The telomeric DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA.	got7fsn_ti	telomere				This term was made obsolete because the definition was too sequence oriented and too restrictive.	GO:0000781|GO:0000782				True				cellular_component											owl:Class	
GO:1902337	biolink:NamedThing	regulation of apoptotic process involved in morphogenesis	Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.	got7fsn_ti	regulation of morphogenetic apoptosis|regulation of apoptosis involved in development|regulation of apoptosis involved in morphogenesis						sart	2013-07-29T15:03:16Z						biological_process											owl:Class	
GO:0033296	biolink:NamedThing	rhamnose binding	Binding to the D- or L-enantiomer of rhamnose.	got7fsn_ti														molecular_function											owl:Class	
GO:0015417	biolink:NamedThing	ABC-type polyamine transporter activity	Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).	got7fsn_ti	spermidine-importing ATPase activity|ATPase-coupled polyamine transmembrane transporter activity|polyamine ABC transporter|ATP-dependent polyamine transmembrane transporter activity|polyamine porter activity|polyamine-importing ATPase activity|spermidine porter activity|polyamine-transporting ATPase activity|ATPase-coupled spermidine transmembrane transporter activity										GO:0015595	MetaCyc:ABC-24-RXN|EC:7.6.2.11|RHEA:29999|MetaCyc:3.6.3.31-RXN		molecular_function											owl:Class	
GO:0043523	biolink:NamedThing	regulation of neuron apoptotic process	Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.	got7fsn_ti	regulation of apoptosis of neuronal cells|regulation of neuronal cell programmed cell death|regulation of apoptosis of neurons|regulation of programmed cell death of neuronal cells|regulation of neuron programmed cell death|regulation of programmed cell death, neurons|regulation of neuron apoptosis													biological_process											owl:Class	
GO:1900938	biolink:NamedThing	regulation of (Z)-nonadeca-1,14-diene metabolic process	Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.	got7fsn_ti	regulation of (Z)-nonadeca-1,14-diene metabolism						tt	2012-06-14T03:15:37Z						biological_process											owl:Class	
GO:0019431	biolink:NamedThing	acetyl-CoA biosynthetic process from ethanol	The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde.	got7fsn_ti	acetyl-CoA formation from ethanol|acetyl-CoA synthesis from ethanol|acetyl-CoA anabolism from ethanol											MetaCyc:ETOH-ACETYLCOA-ANA-PWY		biological_process											owl:Class	
GO:0002582	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.	got7fsn_ti	positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II													biological_process											owl:Class	
GO:1904210	biolink:NamedThing	VCP-NPL4-UFD1 AAA ATPase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex.	got7fsn_ti	VCP-NPL4-UFD1 AAA ATPase complex formation|Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|p97-Ufd1-Npl4 complex assembly|Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|p97-Ufd1-Npl4 complex formation						bf	2015-05-14T10:34:36Z						biological_process											owl:Class	
GO:1901769	biolink:NamedThing	carbapenem biosynthetic process	The chemical reactions and pathways resulting in the formation of carbapenem.	got7fsn_ti	carbapenem formation|carbapenem anabolism|carbapenem biosynthesis|carbapenem synthesis						yaf	2013-01-15T10:09:06Z						biological_process											owl:Class	
GO:2001014	biolink:NamedThing	regulation of skeletal muscle cell differentiation	Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.	got7fsn_ti							yaf	2011-08-11T08:54:37Z						biological_process											owl:Class	
GO:2001073	biolink:NamedThing	cyclodextrin binding	Binding to cyclodextrin.	got7fsn_ti							jl	2011-09-14T12:24:30Z						molecular_function											owl:Class	
GO:1901382	biolink:NamedThing	regulation of chorionic trophoblast cell proliferation	Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.	got7fsn_ti							vk	2012-10-01T10:03:13Z						biological_process											owl:Class	
GO:2000889	biolink:NamedThing	cellodextrin metabolic process	The chemical reactions and pathways involving a cellodextrin.	got7fsn_ti	cellodextrin metabolism						jl	2011-07-28T01:00:04Z						biological_process											owl:Class	
GO:0051621	biolink:NamedThing	regulation of norepinephrine uptake	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.	got7fsn_ti	regulation of norepinephrine import|regulation of noradrenaline uptake|regulation of levarterenol uptake													biological_process											owl:Class	
GO:1900299	biolink:NamedThing	positive regulation of hexasaccharide transport	Any process that activates or increases the frequency, rate or extent of hexasaccharide transport.	got7fsn_ti	upregulation of hexasaccharide transport|up-regulation of hexasaccharide transport|activation of hexasaccharide transport|up regulation of hexasaccharide transport						tt	2012-04-05T07:44:49Z						biological_process											owl:Class	
GO:0106202	biolink:NamedThing	obsolete translocase activity acting on amino acids and peptides linked to a decarboxylation reaction	OBSOLETE. Catalysis of the translocation of amno acids and peptides linked to a decarboxylation reaction.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:30:36Z		True		EC:7.4.4.-		molecular_function											owl:Class	
GO:1904851	biolink:NamedThing	positive regulation of establishment of protein localization to telomere	Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.	got7fsn_ti	activation of establishment of protein localization to chromosome, telomeric region|up-regulation of establishment of protein localization to chromosome, telomeric region|positive regulation of establishment of protein localization to chromosome, telomeric region|up regulation of establishment of protein localisation to telomere|activation of establishment of protein localization to telomere|up regulation of establishment of protein localization to telomere|up-regulation of establishment of protein localisation to telomere|upregulation of establishment of protein localisation to telomere|positive regulation of establishment of protein localisation to telomere|up regulation of establishment of protein localization to chromosome, telomeric region|activation of establishment of protein localisation to telomere|upregulation of establishment of protein localization to telomere|up-regulation of establishment of protein localization to telomere|upregulation of establishment of protein localization to chromosome, telomeric region						nc	2015-12-10T15:37:58Z						biological_process											owl:Class	
GO:1905396	biolink:NamedThing	cellular response to flavonoid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.	got7fsn_ti							sl	2016-08-24T15:01:02Z						biological_process											owl:Class	
GO:0051949	biolink:NamedThing	negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.	got7fsn_ti	negative regulation of 4-aminobutyrate uptake during transmission of nerve impulse|negative regulation of GABA uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid reuptake|negative regulation of 4-aminobutyrate reuptake|negative regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|downregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of GABA reuptake|negative regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|down-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|down regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|inhibition of gamma-aminobutyric acid uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0060194	biolink:NamedThing	regulation of antisense RNA transcription	Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0120265	biolink:NamedThing	negative regulation of chromosome attachment to the nuclear envelope	Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope.	got7fsn_ti	down regulation of chromosome attachment to the nuclear envelope|downregulation of chromosome attachment to the nuclear envelope|inhibition of chromosome attachment to the nuclear envelope|down-regulation of chromosome attachment to the nuclear envelope	https://github.com/geneontology/go-ontology/issues/20020					krc	2020-09-29T20:30:32Z						biological_process											owl:Class	
GO:1903867	biolink:NamedThing	extraembryonic membrane development	The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure.	got7fsn_ti							cjm	2015-02-05T00:42:16Z						biological_process											owl:Class	
GO:0075164	biolink:NamedThing	obsolete negative regulation of G-protein beta subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0010794	biolink:NamedThing	regulation of dolichol biosynthetic process	Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.	got7fsn_ti														biological_process											owl:Class	
GO:0015517	biolink:NamedThing	galactose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).	got7fsn_ti	galactose:hydrogen symporter activity|lactose, galactose:hydrogen symporter activity													molecular_function											owl:Class	
GO:1905830	biolink:NamedThing	positive regulation of prostaglandin catabolic process	Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process.	got7fsn_ti	upregulation of prostaglandin degradation|activation of prostaglandin breakdown|up-regulation of prostaglandin degradation|up-regulation of prostaglandin catabolism|upregulation of prostaglandin catabolic process|activation of prostaglandin catabolism|positive regulation of prostaglandin breakdown|up-regulation of prostaglandin catabolic process|up regulation of prostaglandin catabolism|up regulation of prostaglandin catabolic process|activation of prostaglandin catabolic process|positive regulation of prostaglandin degradation|upregulation of prostaglandin breakdown|upregulation of prostaglandin catabolism|up-regulation of prostaglandin breakdown|up regulation of prostaglandin degradation|positive regulation of prostaglandin catabolism|activation of prostaglandin degradation|up regulation of prostaglandin breakdown						sl	2017-01-16T21:36:56Z						biological_process											owl:Class	
GO:1905715	biolink:NamedThing	regulation of cornification	Any process that modulates the frequency, rate or extent of cornification.	got7fsn_ti							pga	2016-11-24T13:52:55Z						biological_process											owl:Class	
GO:0072469	biolink:NamedThing	obsolete detection of stimulus involved in cell size control checkpoint	OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a cell size control checkpoint.	got7fsn_ti	cell size control checkpoint sensor mechanism|cell size control checkpoint sensor process|sensing involved in cell size control checkpoint|detection of stimulus involved in mitotic cell cycle cell size control checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:46:08Z		True				biological_process											owl:Class	
GO:1900220	biolink:NamedThing	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis	Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis.	got7fsn_ti	semaphorin-plexin signalling pathway of bone trabecula morphogenesis|semaphorin-plexin signaling pathway of bone trabecula morphogenesis						vk	2012-03-22T01:13:56Z						biological_process											owl:Class	
GO:1901008	biolink:NamedThing	(S)-scoulerine catabolic process	The chemical reactions and pathways resulting in the breakdown of (S)-scoulerine.	got7fsn_ti	(S)-scoulerine breakdown|(S)-scoulerine catabolism|(S)-scoulerine degradation						yaf	2012-06-15T10:46:10Z						biological_process											owl:Class	
PR:000001376	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071238	biolink:NamedThing	cellular response to brefeldin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.	got7fsn_ti							mah	2009-12-03T02:25:52Z						biological_process											owl:Class	
GO:1905435	biolink:NamedThing	regulation of histone H3-K4 trimethylation	Any process that modulates the frequency, rate or extent of histone H3-K4 trimethylation.	got7fsn_ti							hbye	2016-09-14T13:08:55Z						biological_process											owl:Class	
GO:1901452	biolink:NamedThing	negative regulation of response to benzene	Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene.	got7fsn_ti	downregulation of response to benzene|down-regulation of response to benzene|inhibition of response to benzene|down regulation of response to benzene						tt	2012-10-02T14:20:23Z						biological_process											owl:Class	
GO:0072367	biolink:NamedThing	obsolete regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of lipid transport by regulation of transcription from an RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:17:54Z		True				biological_process											owl:Class	
GO:2000813	biolink:NamedThing	negative regulation of barbed-end actin filament capping	Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping.	got7fsn_ti	negative regulation of barbed-end actin capping activity|negative regulation of plus-end F-actin capping activity|negative regulation of barbed-end F-actin capping activity|negative regulation of plus-end actin filament capping activity						rl	2011-07-07T04:08:18Z						biological_process											owl:Class	
GO:0017129	biolink:NamedThing	triglyceride binding	Binding to a triester of glycerol.	got7fsn_ti	triacylglycerol binding													molecular_function											owl:Class	
GO:1903211	biolink:NamedThing	mitotic recombination involved in replication fork processing	Any mitotic recombination that is involved in replication fork processing.	got7fsn_ti	mitotic recombination involved in recovery from replication fork stalling|mitotic recombination involved in collapsed replication fork processing|mitotic recombination involved in replication restart|mitotic recombination involved in recovery from replication fork arrest|mitotic recombination involved in replication fork restart						mah	2014-07-24T09:33:40Z						biological_process											owl:Class	
GO:1903471	biolink:NamedThing	regulation of mitotic actomyosin contractile ring contraction	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction.	got7fsn_ti	regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of mitotic actomyosin contractile ring constriction|regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/21855					vw	2014-09-23T14:10:22Z						biological_process											owl:Class	
GO:0010937	biolink:NamedThing	regulation of cytoplasmic microtubule depolymerization	Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.	got7fsn_ti														biological_process											owl:Class	
GO:0071408	biolink:NamedThing	cellular response to cycloalkane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.	got7fsn_ti							mah	2009-12-14T02:57:15Z						biological_process											owl:Class	
GO:1902466	biolink:NamedThing	positive regulation of histone H3-K27 trimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation.	got7fsn_ti	up-regulation of histone H3-K27 trimethylation|up regulation of histone H3-K27 trimethylation|upregulation of histone H3-K27 trimethylation|activation of histone H3-K27 trimethylation						krc	2013-10-22T14:59:19Z						biological_process											owl:Class	
GO:0003202	biolink:NamedThing	endocardial cushion to mesenchymal transition involved in cardiac skeleton development	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton.	got7fsn_ti							dph	2009-10-08T01:39:57Z						biological_process											owl:Class	
GO:0010122	biolink:NamedThing	arginine catabolic process to alanine via ornithine	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine.	got7fsn_ti	arginine breakdown to alanine via ornithine|arginine degradation to alanine via ornithine											MetaCyc:ARGORNPROST-PWY		biological_process											owl:Class	
GO:0046561	biolink:NamedThing	obsolete penicillopepsin activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving Gly20-Glu in the B chain of insulin. Clots milk, and activates trypsinogen.	got7fsn_ti	Penicillium expansum acid proteinase activity|Penicillium roqueforti acid proteinase activity|Penicillium aspartic proteinase activity|Penicillium janthinellum aspartic proteinase activity|Penicillium citrinum acid proteinase activity|Penicillium citrinum aspartic proteinase activity|peptidase A activity|Penicillium caseicolum aspartic proteinase activity|Penicillium cyclopium acid proteinase activity|Penicillium expansum aspartic proteinase activity|penicillopepsin activity|acid protease A|Penicillium janthinellum acid proteinase activity|Penicillium janthinellum aspartic protease activity|Penicillium duponti aspartic proteinase activity			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0045042	biolink:NamedThing	obsolete protein import into mitochondrial intermembrane space, conservative	OBSOLETE. The conservative import of proteins into the mitochondrial intermembrane space. The entire protein enters the matrix, and then the second targeting sequence directs the protein, presumably bound to a matrix protein, across the inner membrane to the intermembrane space.	got7fsn_ti	conservative mitochondrial intermembrane space protein import|conservative protein transport into mitochondrial intermembrane space|conservative mitochondrial IMS protein import|protein transport into mitochondrial intermembrane space, conservative|protein transport into mitochondrial IMS, conservative|conservative protein transport into mitochondrial IMS|protein import into mitochondrial intermembrane space, conservative|protein import into mitochondrial IMS, conservative				This term was made obsolete because there is no 'conservative' process of protein import into the mitochondrial intermembrane space that is distinct from the more general parent; furthermore, 'conservative' is used in the literature to describe a pathway of import into the inner membrane rather than into the intermembrane space.	GO:0045041|GO:0045039				True				biological_process											owl:Class	
GO:0009671	biolink:NamedThing	nitrate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in).	got7fsn_ti	nitrate(chlorate):hydrogen symporter activity|nitrate(chlorate):proton symporter activity|nitrate:hydrogen symporter activity													molecular_function											owl:Class	
GO:1905571	biolink:NamedThing	interleukin-10 receptor complex	A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors.	got7fsn_ti	IL-10 receptor complex|interleukin-10-receptor complex|IL10 receptor complex|IL-10-receptor complex				An example of this is IL10RA in human (UniProt symbol Q13651) in PMID:16982608 (inferred from physical interaction).		bhm	2016-10-19T09:45:22Z						cellular_component											owl:Class	
GO:0140204	biolink:NamedThing	pyridoxal import across plasma membrane	The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-02-21T19:17:27Z						biological_process											owl:Class	
GO:1904083	biolink:NamedThing	obsolete regulation of epiboly	OBSOLETE. Any process that modulates the frequency, rate or extent of epiboly.	got7fsn_ti	regulation of epiboly				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2015-03-25T10:53:34Z		True				biological_process											owl:Class	
GO:0043519	biolink:NamedThing	regulation of myosin II filament organization	Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.	got7fsn_ti	regulation of myosin II filament organisation|regulation of myosin II filament assembly or disassembly													biological_process											owl:Class	
GO:0002257	biolink:NamedThing	negative regulation of kinin cascade	Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade.	got7fsn_ti	downregulation of kinin cascade|down-regulation of kinin cascade|down regulation of kinin cascade|inhibition of kinin cascade													biological_process											owl:Class	
GO:0070170	biolink:NamedThing	regulation of tooth mineralization	Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.	got7fsn_ti														biological_process											owl:Class	
GO:1902012	biolink:NamedThing	poly(ribitol phosphate) teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid.	got7fsn_ti	poly(ribitol phosphate) teichoic acid formation|poly(ribitol phosphate) teichoic acid biosynthesis|poly(ribitol phosphate) teichoic acid synthesis|poly(ribitol phosphate) teichoic acid anabolism						tb	2013-03-22T15:43:40Z						biological_process											owl:Class	
GO:0106088	biolink:NamedThing	regulation of cell adhesion involved in sprouting angiogenesis	Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.	got7fsn_ti							hjd	2018-01-22T18:24:12Z						biological_process											owl:Class	
GO:0051004	biolink:NamedThing	regulation of lipoprotein lipase activity	Any process that modulates the activity of the enzyme lipoprotein lipase.	got7fsn_ti														biological_process											owl:Class	
GO:0003268	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast cell proliferation|fibroblast growth factor receptor signalling pathway involved in regulation of secondary heart field cardioblast cell proliferation|fibroblast growth factor receptor signaling pathway involved in regulation of second heart field cardioblast cell proliferation						dph	2009-10-15T02:43:03Z						biological_process											owl:Class	
GO:1903283	biolink:NamedThing	negative regulation of glutathione peroxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity.	got7fsn_ti	down regulation of selenium-glutathione peroxidase activity|down regulation of glutathione peroxidase activity|inhibition of non-selenium glutathione peroxidase activity|inhibition of reduced glutathione peroxidase activity|inhibition of selenium-glutathione peroxidase activity|negative regulation of glutathione:hydrogen-peroxide oxidoreductase activity|downregulation of GSH peroxidase activity|down regulation of reduced glutathione peroxidase activity|negative regulation of selenium-glutathione peroxidase activity|down regulation of non-selenium glutathione peroxidase activity|inhibition of glutathione:hydrogen-peroxide oxidoreductase activity|downregulation of glutathione:hydrogen-peroxide oxidoreductase activity|down-regulation of glutathione:hydrogen-peroxide oxidoreductase activity|downregulation of glutathione peroxidase activity|downregulation of reduced glutathione peroxidase activity|down-regulation of selenium-glutathione peroxidase activity|down-regulation of reduced glutathione peroxidase activity|down-regulation of glutathione peroxidase activity|inhibition of GSH peroxidase activity|down regulation of glutathione:hydrogen-peroxide oxidoreductase activity|negative regulation of reduced glutathione peroxidase activity|down-regulation of non-selenium glutathione peroxidase activity|down-regulation of GSH peroxidase activity|inhibition of glutathione peroxidase activity|negative regulation of non-selenium glutathione peroxidase activity|downregulation of non-selenium glutathione peroxidase activity|negative regulation of GSH peroxidase activity|down regulation of GSH peroxidase activity|downregulation of selenium-glutathione peroxidase activity						bf	2014-08-11T13:14:22Z						biological_process											owl:Class	
GO:0033609	biolink:NamedThing	oxalate metabolic process	The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.	got7fsn_ti	oxalic acid metabolic process|ethanedioate metabolic process|ethanedioic acid metabolic process|oxalate metabolism													biological_process											owl:Class	
GO:1990885	biolink:NamedThing	obsolete protein serine/threonine kinase binding	OBSOLETE. Binding to a protein serine/threonine kinase.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-10-28T20:40:57Z		True				molecular_function											owl:Class	
GO:0007575	biolink:NamedThing	obsolete nucleolar size increase	OBSOLETE. The process of nucleolar expansion.	got7fsn_ti	nucleolar size increase				This term was made obsolete because it does not describe a biological process.	GO:0007571|GO:0007576				True				biological_process											owl:Class	
GO:0002134	biolink:NamedThing	UTP binding	Binding to UTP, uridine 5'-triphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0060981	biolink:NamedThing	cell migration involved in coronary angiogenesis	The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.	got7fsn_ti							dph	2009-10-06T02:49:12Z						biological_process											owl:Class	
GO:0010726	biolink:NamedThing	positive regulation of hydrogen peroxide metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.	got7fsn_ti	positive regulation of hydrogen peroxide metabolism													biological_process											owl:Class	
GO:1905258	biolink:NamedThing	regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.	got7fsn_ti	regulation of nitrosative stress-induced apoptosis|regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress						bf	2016-06-13T17:04:59Z						biological_process											owl:Class	
GO:0008019	biolink:NamedThing	obsolete macrophage receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	macrophage receptor activity				This term was made obsolete because its name is ambiguous, and it was never defined.	GO:0005044|GO:0038187				True				molecular_function											owl:Class	
GO:0098852	biolink:NamedThing	lytic vacuole membrane	The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell.	got7fsn_ti														cellular_component											owl:Class	
GO:0019512	biolink:NamedThing	lactose catabolic process via tagatose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate.	got7fsn_ti	lactose breakdown via tagatose-6-phosphate|lactose degradation via tagatose-6-phosphate											MetaCyc:LACTOSECAT-PWY		biological_process											owl:Class	
GO:0036283	biolink:NamedThing	obsolete positive regulation of transcription factor import into nucleus in response to oxidative stress	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus under conditions of oxidative stress.	got7fsn_ti	positive regulation of transcription factor import into nucleus in response to hydrogen peroxide				The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0042307|GO:0034599	bf	2012-07-11T01:46:10Z		True				biological_process											owl:Class	
GO:0006041	biolink:NamedThing	glucosamine metabolic process	The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.	got7fsn_ti	chitosamine metabolism|chitosamine metabolic process|glucosamine metabolism													biological_process											owl:Class	
GO:1901781	biolink:NamedThing	p-cumate metabolic process	The chemical reactions and pathways involving p-cumate.	got7fsn_ti	p-cumate metabolism						yaf	2013-01-16T10:40:28Z						biological_process											owl:Class	
GO:2000909	biolink:NamedThing	regulation of sterol import	Any process that modulates the frequency, rate or extent of sterol import.	got7fsn_ti	regulation of sterol influx|regulation of sterol uptake						bf	2011-07-29T01:25:10Z						biological_process											owl:Class	
GO:0062225	biolink:NamedThing	negative regulation of somatic muscle development	Any process that decreases the rate, frequency or extent of somatic muscle development.	got7fsn_ti							dph	2020-03-13T19:06:27Z						biological_process											owl:Class	
GO:0090227	biolink:NamedThing	regulation of red or far-red light signaling pathway	Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.	got7fsn_ti	regulation of phytochrome signaling pathway|regulation of red or far-red light signalling pathway						tb	2010-01-19T04:03:29Z						biological_process											owl:Class	
GO:0071947	biolink:NamedThing	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.	got7fsn_ti							mah	2010-10-06T02:06:10Z						biological_process											owl:Class	
GO:0120151	biolink:NamedThing	positive regulation of mitotic actomyosin contractile ring disassembly	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.	got7fsn_ti	positive regulation of mitotic actomyosin ring disassembly|positive regulation of mitotic constriction ring disassembly|positive regulation of mitotic contractile actomyosin ring disassembly|positive regulation of mitotic cytokinetic ring disassembly|positive regulation of mitotic CAR disassembly						krc	2018-04-24T15:06:51Z						biological_process											owl:Class	
GO:1900547	biolink:NamedThing	obsolete negative regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of phenotypic switching.	got7fsn_ti	negative regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		di	2012-05-14T11:40:54Z		True				biological_process											owl:Class	
GO:0030822	biolink:NamedThing	obsolete positive regulation of cAMP catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	positive regulation of 3',5' cAMP catabolic process|positive regulation of cyclic AMP catabolic process|up-regulation of cAMP catabolic process|positive regulation of cAMP degradation|stimulation of cAMP catabolic process|positive regulation of 3',5'-cAMP catabolic process|positive regulation of cAMP breakdown|up regulation of cAMP catabolic process|positive regulation of adenosine 3',5'-cyclophosphate catabolic process|positive regulation of cAMP catabolism|positive regulation of adenosine 3',5'-cyclophosphate catabolism|positive regulation of 3',5'-cAMP catabolism|positive regulation of cyclic AMP catabolism|upregulation of cAMP catabolic process|activation of cAMP catabolic process|positive regulation of 3',5' cAMP catabolism				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.	GO:0071878				True				biological_process											owl:Class	
GO:2000625	biolink:NamedThing	regulation of miRNA catabolic process	Any process that modulates the frequency, rate or extent of miRNA catabolic process.	got7fsn_ti	regulation of microRNA catabolic process						dph	2011-04-18T03:46:35Z						biological_process											owl:Class	
GO:0046984	biolink:NamedThing	regulation of hemoglobin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	got7fsn_ti	regulation of hemoglobin biosynthesis|regulation of haemoglobin biosynthetic process|regulation of hemoglobin formation|regulation of haemoglobin biosynthesis|regulation of hemoglobin anabolism|regulation of hemoglobin synthesis													biological_process											owl:Class	
GO:2000406	biolink:NamedThing	positive regulation of T cell migration	Any process that activates or increases the frequency, rate or extent of T cell migration.	got7fsn_ti	positive regulation of T-cell migration|positive regulation of T-lymphocyte migration|positive regulation of T lymphocyte migration						mah	2011-02-23T10:49:12Z						biological_process											owl:Class	
CHEBI:62069	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098556	biolink:NamedThing	cytoplasmic side of rough endoplasmic reticulum membrane	The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm.	got7fsn_ti							dos	2013-12-03T12:15:44Z						cellular_component											owl:Class	
GO:1902688	biolink:NamedThing	regulation of NAD metabolic process	Any process that modulates the frequency, rate or extent of NAD metabolic process.	got7fsn_ti	regulation of nicotinamide adenine dinucleotide metabolic process|regulation of NAD metabolism|regulation of oxidized nicotinamide adenine dinucleotide metabolic process|regulation of NAD (oxidized) metabolism|regulation of oxidized NAD metabolic process|regulation of oxidized nicotinamide adenine dinucleotide metabolism|regulation of NAD (oxidized) metabolic process|regulation of nicotinamide adenine dinucleotide metabolism|regulation of NAD phosphorylation and dephosphorylation|regulation of oxidized NAD metabolism						di	2014-02-12T18:58:50Z						biological_process											owl:Class	
GO:0046383	biolink:NamedThing	dTDP-rhamnose metabolic process	The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.	got7fsn_ti	dTDP-rhamnose metabolism													biological_process											owl:Class	
GO:0100028	biolink:NamedThing	obsolete regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates conjugation with cellular fusion.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0010940	biolink:NamedThing	positive regulation of necrotic cell death	Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.	got7fsn_ti														biological_process											owl:Class	
GO:0016674	biolink:NamedThing	obsolete oxidoreductase activity, acting on sulfur group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or a related compound, oxygen, NAD, NADP, an iron-sulfur protein, disulfide or a cytochrome.	got7fsn_ti	oxidoreductase activity, acting on sulphur group of donors, other acceptors|oxidoreductase activity, acting on sulfur group of donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016667				True				molecular_function											owl:Class	
GO:0015358	biolink:NamedThing	obsolete amino acid/choline transmembrane transporter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	amino acid/choline transmembrane transporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015220|GO:0015171				True				molecular_function											owl:Class	
GO:0009131	biolink:NamedThing	pyrimidine nucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside monophosphate breakdown|pyrimidine nucleoside monophosphate degradation|pyrimidine nucleoside monophosphate catabolism													biological_process											owl:Class	
GO:0018982	biolink:NamedThing	vanillin metabolic process	The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin.	got7fsn_ti	vanillic aldehyde metabolic process|vanillic aldehyde metabolism|vanillin metabolism											UM-BBD_pathwayID:van		biological_process											owl:Class	
GO:1905597	biolink:NamedThing	positive regulation of low-density lipoprotein particle receptor binding	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding.	got7fsn_ti	upregulation of low-density lipoprotein receptor binding|upregulation of LDL receptor binding|up-regulation of LDL receptor binding|positive regulation of low-density lipoprotein receptor binding|up regulation of low-density lipoprotein receptor binding|upregulation of low-density lipoprotein particle receptor binding|up regulation of low-density lipoprotein particle receptor binding|up-regulation of low-density lipoprotein particle receptor binding|up regulation of LDL receptor binding|positive regulation of LDL receptor binding|up-regulation of low-density lipoprotein receptor binding|activation of low-density lipoprotein particle receptor binding|activation of low-density lipoprotein receptor binding|activation of LDL receptor binding						nc	2016-10-26T10:57:40Z						biological_process											owl:Class	
GO:0075255	biolink:NamedThing	teliospore formation	The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.	got7fsn_ti														biological_process											owl:Class	
GO:0006240	biolink:NamedThing	dCDP biosynthetic process	The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate.	got7fsn_ti	dCDP synthesis|dCDP biosynthesis|dCDP anabolism|dCDP formation													biological_process											owl:Class	
GO:1900464	biolink:NamedThing	negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from RNA polymerase II promoter	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular hyperosmotic salinity response by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of cellular response to hyperosmotic salt stress by negative regulation of transcription from RNA polymerase II promoter						dgf	2012-05-01T07:29:19Z						biological_process											owl:Class	
GO:1901109	biolink:NamedThing	granaticin biosynthetic process	The chemical reactions and pathways resulting in the formation of granaticin.	got7fsn_ti	granaticin biosynthesis|granaticin synthesis|granaticin formation|granaticin anabolism						yaf	2012-07-11T02:51:40Z						biological_process											owl:Class	
CHEBI:39124	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098573	biolink:NamedThing	intrinsic component of mitochondrial membrane	The component of the mitochondrial membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to mitochondrial membrane													cellular_component											owl:Class	
GO:1901573	biolink:NamedThing	obsolete chemical substance catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of chemical substance.	got7fsn_ti	chemical substance breakdown|chemical substance catabolic process|chemical substance degradation|chemical substance catabolism				This term was obsoleted at the TermGenie Gatekeeper stage.		pr	2012-11-04T18:10:36Z		True				biological_process											owl:Class	
GO:0070639	biolink:NamedThing	vitamin D2 metabolic process	The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.	got7fsn_ti	vitamin D2 metabolism|calciferol metabolic process|ergocalciferol metabolic process						mah	2009-05-08T02:11:35Z						biological_process											owl:Class	
GO:0003929	biolink:NamedThing	obsolete RAN small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	RAN small monomeric GTPase activity			GO:0003924	This term was made obsolete because it represents a gene product.	GO:0006606				True				molecular_function											owl:Class	
GO:0075224	biolink:NamedThing	positive regulation of sporangium germination	Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination.	got7fsn_ti	positive regulation of sporangium germination on or near host													biological_process											owl:Class	
GO:0050813	biolink:NamedThing	epothilone metabolic process	The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.	got7fsn_ti	epothilone metabolism													biological_process											owl:Class	
GO:1901519	biolink:NamedThing	aspyridone B metabolic process	The chemical reactions and pathways involving aspyridone B.	got7fsn_ti	aspyridone B metabolism						di	2012-10-18T18:31:40Z						biological_process											owl:Class	
GO:1905926	biolink:NamedThing	obsolete positive regulation of invadopodium assembly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium assembly.	got7fsn_ti	activation of invadopodium formation|up regulation of invadopodium assembly|positive regulation of invadopodium formation|upregulation of invadopodium formation|upregulation of invadopodium assembly|up-regulation of invadopodium formation|activation of invadopodium assembly|up regulation of invadopodium formation|up-regulation of invadopodium assembly				This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:38:48Z		True				biological_process											owl:Class	
GO:0051197	biolink:NamedThing	obsolete positive regulation of coenzyme metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.	got7fsn_ti	positive regulation of coenzyme metabolism|up regulation of coenzyme metabolic process|up-regulation of coenzyme metabolic process|positive regulation of coenzyme and prosthetic group metabolic process|stimulation of coenzyme metabolic process|positive regulation of coenzyme and prosthetic group metabolism|activation of coenzyme metabolic process|upregulation of coenzyme metabolic process				1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True				biological_process											owl:Class	
UBERON:0005123	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903562	biolink:NamedThing	microtubule bundle formation involved in mitotic spindle midzone assembly	Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis.	got7fsn_ti	microtubule bundling involved in spindle midzone biogenesis involved in mitosis|microtubule bundle formation involved in mitotic spindle midzone assembly|microtubule bundling involved in spindle midzone formation involved in mitosis|microtubule bundling involved in spindle midzone assembly involved in mitosis|microtubule bundle formation involved in mitotic spindle midzone formation|microtubule bundling involved in mitotic spindle midzone assembly|microtubule bundle formation involved in spindle midzone assembly involved in mitosis|microtubule bundling involved in mitotic spindle midzone formation						vw	2014-10-23T11:04:56Z						biological_process											owl:Class	
GO:0019343	biolink:NamedThing	cysteine biosynthetic process via cystathionine	The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.	got7fsn_ti	cysteine synthesis via cystathionine|cysteine formation via cystathionine|cysteine anabolism via cystathionine													biological_process											owl:Class	
GO:1901407	biolink:NamedThing	regulation of phosphorylation of RNA polymerase II C-terminal domain	Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.	got7fsn_ti	regulation of CTD domain phosphorylation of RNA polymerase II|regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|regulation of generation of hyperphosphorylated CTD of RNA polymerase II|regulation of generation of II(0) form of RNA polymerase II						vw	2012-10-01T14:39:50Z						biological_process											owl:Class	
GO:1900037	biolink:NamedThing	regulation of cellular response to hypoxia	Any process that modulates the frequency, rate or extent of cellular response to hypoxia.	got7fsn_ti	regulation of cellular response to lowered oxygen tension|regulation of cellular response to hypoxic stress						yaf	2012-01-17T09:29:03Z						biological_process											owl:Class	
GO:1904615	biolink:NamedThing	cellular response to biphenyl	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.	got7fsn_ti							sl	2015-08-27T19:08:49Z						biological_process											owl:Class	
GO:0045151	biolink:NamedThing	acetoin biosynthetic process	The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone.	got7fsn_ti	acetoin synthesis|acetoin anabolism|acetoin formation|acetoin biosynthesis													biological_process											owl:Class	
GO:0001153	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase III transcription factor recruiting	OBSOLETE. The function of binding to an RNA polymerase III (RNAP III) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP III.	got7fsn_ti	RNA polymerase III transcription factor recruiting transcription factor activity				This term was made obsolete in the 2018 Transcription branch revision. This term was redundant with other terms.		krc	2011-01-27T04:45:37Z		True				molecular_function											owl:Class	
GO:0005207	biolink:NamedThing	obsolete extracellular matrix glycoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	extracellular matrix glycoprotein				This term was made obsolete because it describes localization and modification rather than activity.	GO:0005201				True				molecular_function											owl:Class	
GO:0036246	biolink:NamedThing	phytochelatin 2 import into vacuole	The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.	got7fsn_ti	PC2 import into vacuole						bf	2012-05-31T11:09:20Z						biological_process											owl:Class	
GO:1904844	biolink:NamedThing	response to L-glutamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.	got7fsn_ti							sl	2015-12-07T19:39:17Z						biological_process											owl:Class	
GO:2000443	biolink:NamedThing	regulation of toll-like receptor 21 signaling pathway	Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 21 signalling pathway|regulation of TLR21 signaling pathway						bf	2011-03-04T10:31:48Z						biological_process											owl:Class	
GO:2001071	biolink:NamedThing	maltoheptaose binding	Binding to maltoheptaose.	got7fsn_ti							jl	2011-09-14T12:04:30Z						molecular_function											owl:Class	
GO:0006894	biolink:NamedThing	obsolete Golgi to secretory vesicle transport	OBSOLETE. The directed movement of proteins from the Golgi to one of two types of secretory vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. Specialized secretory cells have a second secretory pathway in which soluble proteins and other substances are initially stored in secretory vesicles for later release.	got7fsn_ti	Golgi to secretory vesicle transport, vesicle-mediated|Golgi to secretory vesicle transport				This term was made obsolete because it mixes two processes that can be better captured in separate terms.	GO:0055108|GO:0055107				True				biological_process											owl:Class	
GO:0106247	biolink:NamedThing	negative regulation of poly(A)-specific ribonuclease activity	Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity.	got7fsn_ti							hjd	2020-02-03T19:01:02Z						biological_process											owl:Class	
GO:0042636	biolink:NamedThing	negative regulation of hair cycle	Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.	got7fsn_ti	down regulation of hair cycle|down-regulation of hair cycle|downregulation of hair cycle|inhibition of hair cycle													biological_process											owl:Class	
GO:0019909	biolink:NamedThing	[pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity	Binds to and modulates of the activity of [pyruvate dehydrogenase (lipoamide)] phosphatase.	got7fsn_ti	[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity													molecular_function											owl:Class	
GO:0051845	biolink:NamedThing	obsolete passive evasion of symbiont immune response	OBSOLETE. Any mechanism of immune avoidance that does not directly interfere with the symbiont immune system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	passive evasion of symbiont immune response|passive immune evasion				This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
GO:0019381	biolink:NamedThing	atrazine catabolic process	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide.	got7fsn_ti	atrazine catabolism|atrazine breakdown|atrazine degradation											MetaCyc:P141-PWY		biological_process											owl:Class	
GO:1900333	biolink:NamedThing	regulation of methane biosynthetic process from 3-(methylthio)propionic acid	Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.	got7fsn_ti							tt	2012-04-06T01:56:13Z						biological_process											owl:Class	
GO:0000267	biolink:NamedThing	obsolete cell fraction	OBSOLETE. A generic term for parts of cells prepared by disruptive biochemical techniques.	got7fsn_ti	cell fraction				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005575				True				cellular_component											owl:Class	
GO:0030319	biolink:NamedThing	obsolete cellular di-, tri-valent inorganic anion homeostasis	OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions at the level of a cell.	got7fsn_ti	cellular di-, tri-valent inorganic anion homeostasis				This term was made obsolete because it has been split.	GO:0072502|GO:0072501				True				biological_process											owl:Class	
GO:0008165	biolink:NamedThing	obsolete pyrethroid resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	pyrethroid resistance			GO:0046684	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0140140	biolink:NamedThing	mitochondrial guanine nucleotide transmembrane transport	The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							pg	2017-11-24T13:26:17Z						biological_process											owl:Class	
GO:0008304	biolink:NamedThing	obsolete eukaryotic translation initiation factor 4 complex	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	eIF-4|eukaryotic translation initiation factor 4 complex			GO:0016281	This term was made obsolete because more specific terms were created.					True				cellular_component											owl:Class	
GO:1902979	biolink:NamedThing	mitotic DNA replication termination	Any DNA replication termination involved in mitotic cell cycle DNA replication.	got7fsn_ti	DNA replication termination involved in mitotic cell cycle DNA replication						jl	2014-05-06T19:19:49Z						biological_process											owl:Class	
GO:0070538	biolink:NamedThing	oleic acid binding	Binding to oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:2000016	biolink:NamedThing	negative regulation of determination of dorsal identity	Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.	got7fsn_ti	negative regulation of determination of adaxial identity						jl	2010-07-15T03:27:55Z						biological_process											owl:Class	
GO:0051115	biolink:NamedThing	obsolete enzyme active site formation via 1'-(phospho-5'-uridine)-L-histidine	OBSOLETE. The transient uridylylation of peptidyl-histidine to form 1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:8794735.	GO:0017103				True		RESID:AA0372		biological_process											owl:Class	
GO:0010391	biolink:NamedThing	glucomannan metabolic process	The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units.	got7fsn_ti	glucomannan metabolism													biological_process											owl:Class	
GO:0110026	biolink:NamedThing	regulation of DNA strand resection involved in replication fork processing	Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing.	got7fsn_ti							kmv	2017-07-05T18:21:06Z						biological_process											owl:Class	
GO:0019022	biolink:NamedThing	obsolete RNA viral genome	OBSOLETE. A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:0098702	biolink:NamedThing	adenine import across plasma membrane	The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	adenine import into cell						dph	2012-12-06T14:51:42Z			GO:0061488			biological_process											owl:Class	
GO:0014746	biolink:NamedThing	regulation of tonic skeletal muscle contraction	Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
GO:0048395	biolink:NamedThing	regulation of intermediate mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination.	got7fsn_ti														biological_process											owl:Class	
GO:0009478	biolink:NamedThing	obsolete cytochrome c554	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytochrome c554				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:1904526	biolink:NamedThing	regulation of microtubule binding	Any process that modulates the frequency, rate or extent of microtubule binding.	got7fsn_ti	regulation of microtubule severing activity|regulation of microtubule/chromatin interaction						als	2015-07-30T10:32:13Z						biological_process											owl:Class	
GO:0030834	biolink:NamedThing	regulation of actin filament depolymerization	Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament.	got7fsn_ti	regulation of actin depolymerization													biological_process											owl:Class	
GO:1904618	biolink:NamedThing	positive regulation of actin binding	Any process that activates or increases the frequency, rate or extent of actin binding.	got7fsn_ti	activation of membrane associated actin binding|positive regulation of membrane associated actin binding|upregulation of actin binding|up regulation of actin binding|up-regulation of membrane associated actin binding|upregulation of membrane associated actin binding|up-regulation of actin binding|activation of actin binding|up regulation of membrane associated actin binding						mr	2015-08-27T19:09:08Z						biological_process											owl:Class	
GO:0032487	biolink:NamedThing	regulation of Rap protein signal transduction	Any process that modulates the frequency, rate or extent of Rap protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:0033051	biolink:NamedThing	aminophosphonate metabolic process	The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group.	got7fsn_ti	aminophosphonate metabolism											KEGG_PATHWAY:map00440		biological_process											owl:Class	
GO:0033070	biolink:NamedThing	ansamycin biosynthetic process	The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.	got7fsn_ti	ansamycin biosynthesis|ansamycin formation|ansamycin synthesis|ansamycin anabolism													biological_process											owl:Class	
GO:2000367	biolink:NamedThing	regulation of acrosomal vesicle exocytosis	Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis.	got7fsn_ti	regulation of acrosome exocytosis|regulation of acrosomal granule exocytosis						yaf	2011-02-07T11:52:34Z						biological_process											owl:Class	
GO:2000648	biolink:NamedThing	positive regulation of stem cell proliferation	Any process that activates or increases the frequency, rate or extent of stem cell proliferation.	got7fsn_ti							dph	2011-04-27T01:04:25Z						biological_process											owl:Class	
CHEBI:32892	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002859	biolink:NamedThing	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.	got7fsn_ti	down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|down-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target|downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target													biological_process											owl:Class	
GO:2000438	biolink:NamedThing	negative regulation of monocyte extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation.	got7fsn_ti							bf	2011-03-04T10:24:44Z						biological_process											owl:Class	
GO:0023065	biolink:NamedThing	obsolete signal transmission via blood	OBSOLETE. The process in which a signal is conveyed via blood.	got7fsn_ti	signal transmission via blood				This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052|GO:0010232		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1905000	biolink:NamedThing	regulation of membrane repolarization during atrial cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.	got7fsn_ti	regulation of atrial repolarization|regulation of electrocardiogram QRS complex						rph	2016-03-01T13:28:05Z						biological_process											owl:Class	
GO:0046646	biolink:NamedThing	regulation of gamma-delta T cell proliferation	Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation.	got7fsn_ti	regulation of gamma-delta T lymphocyte proliferation|regulation of gamma-delta T-cell proliferation|regulation of gamma-delta T-lymphocyte proliferation													biological_process											owl:Class	
GO:1904498	biolink:NamedThing	protein localization to mitotic actomyosin contractile ring	Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis.	got7fsn_ti	protein localization to actomyosin contractile ring involved in mitotic cytokinesis|protein localization to actomyosin contractile ring involved in cytokinesis after mitosis|protein localisation to actomyosin contractile ring involved in cytokinesis after mitosis|protein localization to mitotic actomyosin contractile ring|protein localization to actomyosin contractile ring during mitotic cytokinesis|protein localisation to actomyosin contractile ring involved in mitotic cytokinesis						mah	2015-07-22T14:30:57Z						biological_process											owl:Class	
CHEBI:73265	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075274	biolink:NamedThing	negative regulation of zygosporangium development	Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.	got7fsn_ti														biological_process											owl:Class	
GO:1903166	biolink:NamedThing	cellular response to polycyclic arene	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.	got7fsn_ti							mr	2014-07-09T18:33:04Z						biological_process											owl:Class	
GO:0000025	biolink:NamedThing	maltose catabolic process	The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).	got7fsn_ti	maltose breakdown|maltose hydrolysis|malt sugar catabolism|malt sugar catabolic process|maltose degradation											MetaCyc:MALTOSECAT-PWY		biological_process											owl:Class	
GO:0015596	biolink:NamedThing	obsolete glycine betaine/proline porter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in).	got7fsn_ti	glycine betaine/proline porter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015193|GO:0015199|GO:0015187|GO:0015418				True				molecular_function											owl:Class	
GO:0019636	biolink:NamedThing	phosphonoacetate metabolic process	The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue.	got7fsn_ti	phosphonoacetate metabolism											MetaCyc:P483-PWY		biological_process											owl:Class	
GO:0006114	biolink:NamedThing	glycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	got7fsn_ti	glycerol biosynthesis|glycerol synthesis|glycerol anabolism|glycerol formation													biological_process											owl:Class	
GO:0060831	biolink:NamedThing	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.	got7fsn_ti	hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|smoothened signalling pathway involved in dorsal/ventral neural tube patterning|hh signaling pathway involved in dorsal/ventral neural tube patterning						dph	2009-08-11T02:12:58Z						biological_process											owl:Class	
GO:1901699	biolink:NamedThing	cellular response to nitrogen compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.	got7fsn_ti	cellular response to nitrogen molecular entity						pr	2012-12-13T15:06:13Z						biological_process											owl:Class	
GO:0046231	biolink:NamedThing	obsolete carbazole biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.	got7fsn_ti	carbazole biosynthetic process|carbazole anabolism|carbazole synthesis|carbazole biosynthesis|carbazole formation			GO:0018884	This term was made obsolete because carbazole is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0050824	biolink:NamedThing	obsolete water binding	OBSOLETE. Binding to water (H2O).	got7fsn_ti					This term was obsoleted because water binding is non-specific.					True				molecular_function											owl:Class	
GO:0120187	biolink:NamedThing	positive regulation of protein localization to chromatin	Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.	got7fsn_ti	positive regulation of protein localisation to chromatin						krc	2018-07-14T00:21:28Z						biological_process											owl:Class	
GO:0002593	biolink:NamedThing	negative regulation of antigen processing and presentation via MHC class Ib	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.	got7fsn_ti	inhibition of antigen processing and presentation via MHC class Ib|down-regulation of antigen processing and presentation via MHC class Ib|downregulation of antigen processing and presentation via MHC class Ib|down regulation of antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:1900456	biolink:NamedThing	obsolete regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of colony morphology by regulation of transcription from RNA polymerase II promoter|regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter				This term was obsoleted at the TermGenie Gatekeeper stage.		dgf	2012-05-01T05:42:03Z		True				biological_process											owl:Class	
GO:1902448	biolink:NamedThing	positive regulation of shade avoidance	Any process that activates or increases the frequency, rate or extent of shade avoidance.	got7fsn_ti	up-regulation of shade avoidance|activation of shade avoidance|upregulation of shade avoidance|up regulation of shade avoidance						dhl	2013-10-15T21:05:00Z						biological_process											owl:Class	
GO:0015677	biolink:NamedThing	copper ion import	The directed movement of copper ions into a cell or organelle.	got7fsn_ti	copper ion uptake													biological_process											owl:Class	
GO:0006982	biolink:NamedThing	response to lipid hydroperoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.	got7fsn_ti	response to LHPO													biological_process											owl:Class	
GO:1903448	biolink:NamedThing	geraniol biosynthetic process	The chemical reactions and pathways resulting in the formation of geraniol.	got7fsn_ti	geraniol biosynthesis|geraniol anabolism|geraniol formation|geraniol synthesis						di	2014-09-19T08:18:52Z						biological_process											owl:Class	
UBERON:0004291	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015270	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:64545	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900780	biolink:NamedThing	fumiquinazoline C catabolic process	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline C.	got7fsn_ti	fumiquinazoline C breakdown|fumiquinazoline C catabolism|fumiquinazoline C degradation						di	2012-06-04T09:30:51Z						biological_process											owl:Class	
GO:0030821	biolink:NamedThing	obsolete negative regulation of cAMP catabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	got7fsn_ti	negative regulation of cyclic AMP catabolic process|down regulation of cAMP catabolic process|downregulation of cAMP catabolic process|negative regulation of 3',5' cAMP catabolic process|negative regulation of 3',5'-cAMP catabolism|negative regulation of adenosine 3',5'-cyclophosphate catabolic process|inhibition of cAMP catabolic process|down-regulation of cAMP catabolic process|negative regulation of cAMP breakdown|negative regulation of 3',5' cAMP catabolism|negative regulation of adenosine 3',5'-cyclophosphate catabolism|negative regulation of cyclic AMP catabolism|negative regulation of cAMP catabolism|negative regulation of cAMP degradation|negative regulation of 3',5'-cAMP catabolic process				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0098665	biolink:NamedThing	serotonin receptor complex	A protein complex that is capable of serotonin receptor activity.	got7fsn_ti	5HT receptor complex|5-hydroxytryptamine receptor complex|5-HT receptor complex						dos	2016-12-21T12:24:56Z						cellular_component											owl:Class	
GO:0010799	biolink:NamedThing	regulation of peptidyl-threonine phosphorylation	Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	got7fsn_ti														biological_process											owl:Class	
GO:0140343	biolink:NamedThing	phosphatidylserine transfer activity	Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.	got7fsn_ti	intermembrane phosphatidylserine carrier activity						pg	2019-05-16T11:46:19Z						molecular_function											owl:Class	
GO:0005097	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900807	biolink:NamedThing	fumigaclavine C metabolic process	The chemical reactions and pathways involving fumigaclavine C.	got7fsn_ti	fumigaclavine C metabolism						di	2012-06-04T09:59:32Z						biological_process											owl:Class	
CL:0000579	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904110	biolink:NamedThing	obsolete regulation of plus-end directed microfilament motor activity	OBSOLETE. Any process that modulates the frequency, rate or extent of plus-end directed microfilament motor activity.	got7fsn_ti	regulation of plus-end directed actin-filament motor activity|regulation of plus-end directed actin filament motor activity|regulation of barbed-end directed actin-filament motor activity	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140659	kmv	2015-04-03T18:28:24Z		True				biological_process											owl:Class	
GO:1905259	biolink:NamedThing	negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.	got7fsn_ti	down-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|downregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|inhibition of intrinsic apoptotic signaling pathway in response to nitrosative stress|inhibition of nitrosative stress-induced intrinsic apoptotic signaling pathway|down regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|negative regulation of nitrosative stress-induced apoptosis|down regulation of nitrosative stress-induced apoptosis|negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|down regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|downregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|down-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|down-regulation of nitrosative stress-induced apoptosis|downregulation of nitrosative stress-induced apoptosis|inhibition of nitrosative stress-induced apoptosis						bf	2016-06-13T17:05:07Z						biological_process											owl:Class	
GO:0075048	biolink:NamedThing	obsolete cell wall strengthening in symbiont involved in entry into host	OBSOLETE. A process in which the cell wall of the symbiont is strengthened or thickened during penetration into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	cell wall thickening in symbiont during entry into host|symbiont cell wall strengthening during entry into host|cell wall strengthening in symbiont during entry into host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0060695	biolink:NamedThing	negative regulation of cholesterol transporter activity	Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.	got7fsn_ti							dph	2009-06-08T02:08:34Z						biological_process											owl:Class	
GO:1904119	biolink:NamedThing	negative regulation of otic vesicle morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis.	got7fsn_ti	downregulation of otic vesicle morphogenesis|down regulation of otic vesicle morphogenesis|down-regulation of otic vesicle morphogenesis|inhibition of otic vesicle morphogenesis						pga	2015-04-07T14:01:02Z						biological_process											owl:Class	
GO:0019286	biolink:NamedThing	glycine betaine biosynthetic process from glycine	The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine.	got7fsn_ti	glycine betaine synthesis from glycine|glycine betaine formation from glycine|N-trimethylglycine biosynthetic process from glycine|glycine betaine anabolism from glycine|N-trimethylglycine biosynthesis from glycine											MetaCyc:P541-PWY		biological_process											owl:Class	
GO:0006027	biolink:NamedThing	glycosaminoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.	got7fsn_ti	glycosaminoglycan degradation|glycosaminoglycan catabolism|glycosaminoglycan breakdown													biological_process											owl:Class	
GO:0097364	biolink:NamedThing	stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential.	got7fsn_ti							pr	2012-07-25T04:08:33Z						molecular_function											owl:Class	
GO:2000811	biolink:NamedThing	negative regulation of anoikis	Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.	got7fsn_ti	negative regulation of suspension induced apoptosis|negative regulation of detachment induced cell death						pr	2011-07-07T09:42:20Z						biological_process											owl:Class	
GO:0030712	biolink:NamedThing	negative regulation of border follicle cell delamination	Any process that decreases the frequency, rate or extent of border cell delamination.	got7fsn_ti	negative regulation of border cell delamination|down-regulation of border follicle cell delamination|down regulation of border follicle cell delamination|downregulation of border follicle cell delamination|inhibition of border follicle cell delamination													biological_process											owl:Class	
GO:0099191	biolink:NamedThing	trans-synaptic signaling by BDNF	Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.	got7fsn_ti	trans-synaptic signaling by brain-derived neurotrophic factor						dos	2017-12-20T15:48:33Z						biological_process											owl:Class	
GO:1901378	biolink:NamedThing	organic heteropentacyclic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound.	got7fsn_ti	organic heteropentacyclic compound synthesis|organic heteropentacyclic compound formation|organic heteropentacyclic compound biosynthesis|organic heteropentacyclic compound anabolism						bf	2012-09-28T12:52:09Z						biological_process											owl:Class	
GO:0009129	biolink:NamedThing	pyrimidine nucleoside monophosphate metabolic process	The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0052356	biolink:NamedThing	obsolete catabolism by host of symbiont cell wall chitin	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0030977	biolink:NamedThing	taurine binding	Binding to taurine.	got7fsn_ti														molecular_function											owl:Class	
GO:0030933	biolink:NamedThing	chloroplast ADPG pyrophosphorylase complex	An ADPG pyrophosphorylase complex found in the chloroplast.	got7fsn_ti														cellular_component											owl:Class	
GO:1901177	biolink:NamedThing	lycopene biosynthetic process	The chemical reactions and pathways resulting in the formation of lycopene.	got7fsn_ti	lycopene biosynthesis|lycopene synthesis|lycopene formation|lycopene anabolism						yaf	2012-07-19T09:48:49Z						biological_process											owl:Class	
GO:2000037	biolink:NamedThing	regulation of stomatal complex patterning	Any process that modulates the frequency, rate or extent of stomatal complex patterning.	got7fsn_ti							tb	2010-08-05T11:35:47Z						biological_process											owl:Class	
GO:0034486	biolink:NamedThing	vacuolar transmembrane transport	The process in which a solute is transported from one side of the vacuolar membrane to the other.	got7fsn_ti	vacuolar membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:1990139	biolink:NamedThing	protein localization to nuclear periphery	A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.	got7fsn_ti							mah	2013-07-09T13:35:49Z						biological_process											owl:Class	
GO:0032733	biolink:NamedThing	positive regulation of interleukin-10 production	Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.	got7fsn_ti	positive regulation of IL-10 production|up-regulation of interleukin-10 production|up regulation of interleukin-10 production|stimulation of interleukin-10 production|positive regulation of interleukin-10 secretion|activation of interleukin-10 production|upregulation of interleukin-10 production|positive regulation of interleukin-10 biosynthetic process										GO:0045082|GO:2001181			biological_process											owl:Class	
GO:0042822	biolink:NamedThing	pyridoxal phosphate metabolic process	The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.	got7fsn_ti	pyridoxal phosphate metabolism|active vitamin B6 metabolic process|active vitamin B6 metabolism													biological_process											owl:Class	
CHEBI:64476	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140311	biolink:NamedThing	protein sequestering activity	The selective interaction of a protein with a specific protein, to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	got7fsn_ti							pg	2019-03-26T14:34:16Z						molecular_function											owl:Class	
GO:0035656	biolink:NamedThing	obsolete kinesin-associated melanosomal adaptor activity	OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes.	got7fsn_ti	kinesin-melanosome adaptor activity	https://github.com/geneontology/go-ontology/issues/17668			This term was obsoleted because it represents the function of a specific protein.	GO:0030674|GO:0008093	bf	2011-01-27T01:32:51Z		True				molecular_function											owl:Class	
GO:0008450	biolink:NamedThing	obsolete O-sialoglycoprotein endopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of O-sialoglycoproteins; cleaves the -Arg31-Asp32- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated.	got7fsn_ti	O-sialoglycoprotein endopeptidase activity|glycophorin A proteinase activity|sialoglycoprotease activity|glycoprotease activity|glycoproteinase activity|sialoglycoproteinase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0007070	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter, mitotic|negative regulation of transcription from Pol II promoter during mitosis|down-regulation of transcription from RNA polymerase II promoter during mitosis|downregulation of transcription from RNA polymerase II promoter during mitosis|inhibition of transcription from RNA polymerase II promoter during mitosis|down regulation of transcription from RNA polymerase II promoter during mitosis|mitotic repression of transcription from Pol II promoter	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0000122|GO:0044772				True				biological_process											owl:Class	
GO:0016739	biolink:NamedThing	obsolete oxidoreductase activity, acting on other substrates	OBSOLETE. A grouping term for oxidoreductase that cannot be more accurately categorized.	got7fsn_ti	oxidoreductase activity, acting on other substrates				This term was made obsolete because it was an unnecessary grouping term.	GO:0016491				True				molecular_function											owl:Class	
CHEBI:24158	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0100035	biolink:NamedThing	obsolete negative regulation of transmembrane transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates transmembrane transport.	got7fsn_ti					The term was obsoleted because it is better represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
CHEBI:2588	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901753	biolink:NamedThing	leukotriene A4 biosynthetic process	The chemical reactions and pathways resulting in the formation of leukotriene A4.	got7fsn_ti	leukotriene A4 anabolism|eoxin A4 biosynthesis|leukotriene A4 formation|leukotriene A4 biosynthesis|leukotriene A4 synthesis|LTA4 biosynthesis	https://github.com/geneontology/go-ontology/issues/18848					yaf	2013-01-14T11:05:09Z						biological_process											owl:Class	
GO:1901190	biolink:NamedThing	regulation of formation of translation initiation ternary complex	Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.	got7fsn_ti	regulation of translation initiation ternary complex assembly						ss	2012-07-25T02:26:58Z						biological_process											owl:Class	
GO:0072727	biolink:NamedThing	cellular response to CCCP	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus.	got7fsn_ti	cellular response to carbonyl cyanide m-chlorophenyl hydrazone						mah	2012-05-31T11:16:43Z						biological_process											owl:Class	
GO:1900287	biolink:NamedThing	positive regulation of cellotriose transport	Any process that activates or increases the frequency, rate or extent of cellotriose transport.	got7fsn_ti	up regulation of cellotriose transport|activation of cellotriose transport|up-regulation of cellotriose transport|upregulation of cellotriose transport						tt	2012-04-05T05:57:05Z						biological_process											owl:Class	
GO:1904011	biolink:NamedThing	cellular response to Aroclor 1254	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.	got7fsn_ti							sl	2015-03-06T18:35:06Z						biological_process											owl:Class	
GO:1902069	biolink:NamedThing	negative regulation of sphingolipid mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling.	got7fsn_ti	down regulation of sphingolipid mediated signaling pathway|down-regulation of sphingolipid mediated signaling pathway|down regulation of sphingolipid signaling pathway|down-regulation of sphingolipid signaling pathway|inhibition of sphingolipid signaling pathway|inhibition of sphingolipid mediated signaling pathway|downregulation of sphingolipid mediated signaling pathway|negative regulation of sphingolipid signaling pathway|downregulation of sphingolipid signaling pathway						bf	2013-04-18T13:24:51Z						biological_process											owl:Class	
GO:1901147	biolink:NamedThing	mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis.	got7fsn_ti							pr	2012-07-13T02:41:12Z						biological_process											owl:Class	
GO:2000529	biolink:NamedThing	positive regulation of myeloid dendritic cell chemotaxis	Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.	got7fsn_ti							ebc	2011-03-23T12:18:45Z						biological_process											owl:Class	
GO:0003782	biolink:NamedThing	obsolete F-actin capping activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	F-actin capping activity			GO:0051016	This term was made obsolete because it describes a biological process.					True				molecular_function											owl:Class	
GO:0045647	biolink:NamedThing	negative regulation of erythrocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.	got7fsn_ti	negative regulation of RBC differentiation|negative regulation of red blood cell differentiation|downregulation of erythrocyte differentiation|inhibition of erythrocyte differentiation|down regulation of erythrocyte differentiation|down-regulation of erythrocyte differentiation													biological_process											owl:Class	
GO:0000740	biolink:NamedThing	nuclear membrane fusion	The joining of 2 or more lipid bilayer membranes that surround the nucleus.	got7fsn_ti														biological_process											owl:Class	
GO:0052647	biolink:NamedThing	pentitol phosphate metabolic process	The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule.	got7fsn_ti	pentitol phosphate metabolism						ai	2010-09-22T04:26:28Z						biological_process											owl:Class	
GO:0034758	biolink:NamedThing	positive regulation of iron ion transport	Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	positive regulation of iron transport|stimulation of iron ion transport|upregulation of iron ion transport|up regulation of iron ion transport|up-regulation of iron ion transport|activation of iron ion transport													biological_process											owl:Class	
GO:1902875	biolink:NamedThing	regulation of embryonic pattern specification	Any process that modulates the frequency, rate or extent of embryonic pattern specification.	got7fsn_ti	regulation of ventral/lateral system|regulation of embryonic pattern biosynthesis|regulation of embryonic pattern formation						mr	2014-04-03T15:25:15Z						biological_process											owl:Class	
GO:0018327	biolink:NamedThing	obsolete enzyme active site formation via 1'-phospho-L-histidine	OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:11038361.	GO:0008257				True		RESID:AA0035		biological_process											owl:Class	
GO:0036104	biolink:NamedThing	Kdo2-lipid A biosynthetic process	The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component.	got7fsn_ti	di[3-deoxy-D-manno-octulosonyl]-lipid A biosynthesis|Kdo2-lipid A synthesis|Kdo2-lipid A biosynthesis|Kdo2-lipid A formation|Kdo2-lipid A anabolism|KDO(2)-lipid A biosynthesis						bf	2012-01-27T01:49:23Z						biological_process											owl:Class	
GO:1905810	biolink:NamedThing	regulation of excitatory synapse pruning	Any process that modulates the frequency, rate or extent of excitatory synapse pruning.	got7fsn_ti	regulation of synapse clearance|regulation of synapse elimination|regulation of synapse removal|regulation of synapse disassembly						tb	2017-01-12T02:38:27Z						biological_process											owl:Class	
GO:1902254	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.	got7fsn_ti	inhibition of intrinsic apoptotic signaling pathway by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis|inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway by p53 class mediator|down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator|down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis						rl	2013-06-20T19:41:43Z						biological_process											owl:Class	
GO:1900522	biolink:NamedThing	negative regulation of response to amylopectin	Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin.	got7fsn_ti	down-regulation of response to amylopectin|downregulation of response to amylopectin|inhibition of response to amylopectin|down regulation of response to amylopectin						tt	2012-05-02T04:14:01Z						biological_process											owl:Class	
GO:0010900	biolink:NamedThing	negative regulation of phosphatidylcholine catabolic process	Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	got7fsn_ti														biological_process											owl:Class	
GO:2000629	biolink:NamedThing	negative regulation of miRNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.	got7fsn_ti	negative regulation of microRNA metabolic process						dph	2011-04-18T03:47:58Z						biological_process											owl:Class	
GO:0031156	biolink:NamedThing	regulation of sorocarp development	Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum.	got7fsn_ti	regulation of fruiting body development|regulation of fruiting body formation													biological_process											owl:Class	
GO:0042487	biolink:NamedThing	regulation of odontogenesis of dentin-containing tooth	Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.	got7fsn_ti	regulation of odontogenesis of dentine-containing tooth|regulation of odontogenesis of dentine-containing teeth													biological_process											owl:Class	
GO:0090320	biolink:NamedThing	regulation of chylomicron remnant clearance	Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.	got7fsn_ti							tb	2010-04-30T10:20:26Z						biological_process											owl:Class	
CHEBI:29195	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052504	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont callose deposition	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of defense-related papilla formation in symbiont|induction by organism of defense-related papilla formation in symbiont|positive regulation by organism of defense-related symbiont callose deposition|induction by organism of defense-related symbiont callose deposition				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1902391	biolink:NamedThing	positive regulation of N-terminal peptidyl-serine acetylation	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation.	got7fsn_ti	up-regulation of N-terminal peptidyl-serine acetylation|activation of N-terminal peptidyl-serine acetylation|upregulation of N-terminal peptidyl-serine acetylation|up regulation of N-terminal peptidyl-serine acetylation						al	2013-09-11T14:46:54Z						biological_process											owl:Class	
GO:1903853	biolink:NamedThing	regulation of stress response to copper ion	Any process that modulates the frequency, rate or extent of stress response to copper ion.	got7fsn_ti	regulation of stress response to copper|regulation of response to copper toxicity|regulation of response to copper ion stress						kmv	2015-01-29T20:15:23Z						biological_process											owl:Class	
GO:1902025	biolink:NamedThing	nitrate import	The directed movement of nitrate into a cell or organelle.	got7fsn_ti	nitrate uptake|nitrate influx						tb	2013-03-27T21:32:58Z						biological_process											owl:Class	
GO:0019300	biolink:NamedThing	rhamnose biosynthetic process	The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.	got7fsn_ti	rhamnose synthesis|rhamnose formation|rhamnose anabolism|rhamnose biosynthesis													biological_process											owl:Class	
GO:0006722	biolink:NamedThing	triterpenoid metabolic process	The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units.	got7fsn_ti	triterpene metabolism|triterpene metabolic process|triterpenoid metabolism													biological_process											owl:Class	
GO:0046683	biolink:NamedThing	response to organophosphorus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.	got7fsn_ti	organophosphorus susceptibility/resistance|organophosphorus resistance													biological_process											owl:Class	
GO:0090230	biolink:NamedThing	regulation of centromere complex assembly	Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex.	got7fsn_ti	centromere licensing						tb	2010-01-20T10:20:49Z						biological_process											owl:Class	
GO:1902113	biolink:NamedThing	nucleotide phosphorylation involved in DNA repair	Any nucleotide phosphorylation that is involved in DNA repair.	got7fsn_ti							al	2013-05-13T08:56:02Z						biological_process											owl:Class	
GO:0120289	biolink:NamedThing	positive regulation of aspartic endopeptidase activity, intramembrane cleaving	Any process that increases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20341					krc	2020-11-19T22:27:57Z						biological_process											owl:Class	
CHEBI:64620	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001911	biolink:NamedThing	negative regulation of leukocyte mediated cytotoxicity	Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity.	got7fsn_ti	inhibition of leukocyte mediated cytotoxicity|down-regulation of leukocyte mediated cytotoxicity|negative regulation of leucocyte mediated cytotoxicity|down regulation of leukocyte mediated cytotoxicity|downregulation of leukocyte mediated cytotoxicity|negative regulation of immune cell mediated cytotoxicity													biological_process											owl:Class	
GO:0120182	biolink:NamedThing	regulation of focal adhesion disassembly	Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.	got7fsn_ti							krc	2018-07-12T17:44:29Z						biological_process											owl:Class	
GO:0034128	biolink:NamedThing	negative regulation of MyD88-independent toll-like receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.	got7fsn_ti	negative regulation of MyD88-independent TLR signaling pathway|negative regulation of MyD88-independent toll-like receptor signalling pathway													biological_process											owl:Class	
GO:2001276	biolink:NamedThing	regulation of leucine biosynthetic process	Any process that modulates the frequency, rate or extent of leucine biosynthetic process.	got7fsn_ti	regulation of leucine synthesis|regulation of leucine anabolism|regulation of leucine biosynthesis|regulation of leucine formation						mcc	2011-12-13T03:13:27Z						biological_process											owl:Class	
GO:0034445	biolink:NamedThing	negative regulation of plasma lipoprotein oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma.	got7fsn_ti	inhibition of plasma lipoprotein oxidation|negative regulation of plasma lipoprotein particle oxidation													biological_process											owl:Class	
GO:0009936	biolink:NamedThing	obsolete expansin	OBSOLETE. A group of proteins located within the cell walls of plants, both dicots and grasses, that play an essential role in loosening cell walls during cell growth. They are hydrophobic, non glycosylated proteins of about 30kDa.	got7fsn_ti	expansin				This term was made obsolete because it represents a gene product.	GO:0016049|GO:0009505				True				molecular_function											owl:Class	
GO:0008580	biolink:NamedThing	obsolete cytoskeletal regulator activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytoskeletal regulator activity				This term was made obsolete because 'cytoskeleton' is not an activity, and regulation of its distribution or modification belongs in the process ontology.	GO:0007010				True				molecular_function											owl:Class	
GO:0075515	biolink:NamedThing	obsolete viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane	OBSOLETE. The uptake of a virus into a host cell that begins when material is taken up into plasma membrane caveolae which then pinch off to form endocytic caveolar carriers containing the virus. The caveolar carriers then deliver their viral content to early endosomes, and the process ends when viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane.	got7fsn_ti	viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane|viral entry into host cell via caveolae-mediated endocytosis followed by genetic injection through the endosome membrane				This term was made obsolete because it doesn't represent a genuine process. The term injection is mostly used for prokaryotic viruses where there is no endocytosis.		jl	2011-07-27T02:57:55Z		True				biological_process											owl:Class	
GO:0042677	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075290	biolink:NamedThing	regulation of aplanospore formation	Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.	got7fsn_ti														biological_process											owl:Class	
GO:0042414	biolink:NamedThing	epinephrine metabolic process	The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	got7fsn_ti	adrenaline metabolic process|adrenaline metabolism|epinephrine metabolism													biological_process											owl:Class	
GO:1901692	biolink:NamedThing	regulation of compound eye retinal cell apoptotic process	Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process.	got7fsn_ti							pr	2012-12-12T10:28:35Z						biological_process											owl:Class	
GO:2000594	biolink:NamedThing	positive regulation of metanephric DCT cell differentiation	Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation.	got7fsn_ti	positive regulation of metanephric distal convoluted tubule cell differentiation						yaf	2011-04-11T01:40:41Z						biological_process											owl:Class	
GO:0015921	biolink:NamedThing	lipopolysaccharide export	The directed movement of lipopolysaccharides out of a cell or organelle.	got7fsn_ti	LPS export													biological_process											owl:Class	
GO:0045150	biolink:NamedThing	acetoin catabolic process	The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone.	got7fsn_ti	acetoin catabolism|acetoin degradation|acetoin breakdown													biological_process											owl:Class	
GO:0042457	biolink:NamedThing	ethylene catabolic process	The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.	got7fsn_ti	ethylene breakdown|ethene catabolic process|ethylene degradation|ethylene catabolism|ethene catabolism													biological_process											owl:Class	
GO:1904423	biolink:NamedThing	dehydrodolichyl diphosphate synthase complex	A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.	got7fsn_ti							ew	2015-07-02T19:51:40Z						cellular_component											owl:Class	
GO:0014054	biolink:NamedThing	positive regulation of gamma-aminobutyric acid secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.	got7fsn_ti	up-regulation of gamma-aminobutyric acid secretion|stimulation of gamma-aminobutyric acid secretion|activation of gamma-aminobutyric acid secretion|up regulation of gamma-aminobutyric acid secretion|upregulation of gamma-aminobutyric acid secretion|positive regulation of GABA secretion													biological_process											owl:Class	
GO:0043477	biolink:NamedThing	pigment biosynthetic process involved in pigment accumulation	The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.	got7fsn_ti	pigment biosynthetic process during pigment accumulation													biological_process											owl:Class	
GO:0032604	biolink:NamedThing	granulocyte macrophage colony-stimulating factor production	The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	granulocyte macrophage colony-stimulating factor biosynthetic process|granulocyte macrophage colony stimulating factor production|GM-CSF production										GO:0042253			biological_process											owl:Class	
GO:2000597	biolink:NamedThing	positive regulation of optic nerve formation	Any process that activates or increases the frequency, rate or extent of optic nerve formation.	got7fsn_ti	positive regulation of CN II formation|positive regulation of CN II biosynthesis						yaf	2011-04-11T03:41:39Z						biological_process											owl:Class	
GO:0080170	biolink:NamedThing	hydrogen peroxide transmembrane transport	The process in which hydrogen peroxide is transported across a membrane.	got7fsn_ti	hydrogen peroxide membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		dhl	2010-09-23T05:12:14Z						biological_process											owl:Class	
GO:0062104	biolink:NamedThing	pumilio-response element binding	Binding to a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA.	got7fsn_ti	PRE binding						dph	2019-01-11T13:38:26Z						molecular_function											owl:Class	
GO:0071778	biolink:NamedThing	obsolete WINAC complex	OBSOLETE. A SWI/SNF-type complex that directly interacts with the vitamin D receptor (VDR) through the Williams syndrome transcription factor (WSTF), and mediates the recruitment of unliganded VDR to VDR target sites in promoters. The WINAC complex contains at least 13 subunits, including WSTF, several SWI/SNF components, and DNA replication-related factors.	got7fsn_ti	WINAC complex				This term was made obsolete because the paper describing the characterization of this complex, which was used to create this term, has been retracted.		mah	2010-08-31T12:19:54Z		True				cellular_component											owl:Class	
GO:1900665	biolink:NamedThing	negative regulation of emodin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process.	got7fsn_ti	down regulation of emodin synthesis|inhibition of emodin anabolism|negative regulation of emodin biosynthesis|down regulation of emodin anabolism|inhibition of emodin biosynthesis|down regulation of emodin biosynthesis|down-regulation of emodin formation|inhibition of emodin biosynthetic process|negative regulation of emodin formation|inhibition of emodin formation|down-regulation of emodin anabolism|downregulation of emodin formation|down regulation of emodin formation|negative regulation of emodin synthesis|down-regulation of emodin biosynthetic process|downregulation of emodin synthesis|down regulation of emodin biosynthetic process|downregulation of emodin biosynthesis|downregulation of emodin biosynthetic process|negative regulation of emodin anabolism|down-regulation of emodin synthesis|down-regulation of emodin biosynthesis|downregulation of emodin anabolism|inhibition of emodin synthesis						di	2012-05-22T04:14:58Z						biological_process											owl:Class	
GO:0044430	biolink:NamedThing	obsolete cytoskeletal part	OBSOLETE. Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.	got7fsn_ti	cytoskeletal element|cytoskeleton component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005856				True		NIF_Subcellular:sao1635329413		cellular_component											owl:Class	
GO:1900117	biolink:NamedThing	regulation of execution phase of apoptosis	Any process that modulates the frequency, rate or extent of execution phase of apoptosis.	got7fsn_ti							pr	2012-02-22T11:26:20Z						biological_process											owl:Class	
GO:1900120	biolink:NamedThing	regulation of receptor binding	Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.	got7fsn_ti	regulation of receptor ligand						bf	2012-02-22T11:40:53Z						biological_process											owl:Class	
GO:0046825	biolink:NamedThing	regulation of protein export from nucleus	Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.	got7fsn_ti	regulation of protein export out of nucleus|regulation of protein export from cell nucleus|regulation of protein transport from nucleus to cytoplasm|regulation of protein-nucleus export													biological_process											owl:Class	
GO:1900038	biolink:NamedThing	negative regulation of cellular response to hypoxia	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia.	got7fsn_ti	negative regulation of cellular response to lowered oxygen tension|inhibition of cellular response to hypoxic stress|down regulation of cellular response to hypoxia|downregulation of cellular response to hypoxic stress|down-regulation of cellular response to hypoxic stress|down-regulation of cellular response to lowered oxygen tension|inhibition of cellular response to lowered oxygen tension|inhibition of cellular response to hypoxia|down regulation of cellular response to lowered oxygen tension|down-regulation of cellular response to hypoxia|negative regulation of cellular response to hypoxic stress|downregulation of cellular response to hypoxia|down regulation of cellular response to hypoxic stress|downregulation of cellular response to lowered oxygen tension						yaf	2012-01-17T09:29:16Z						biological_process											owl:Class	
GO:0071393	biolink:NamedThing	cellular response to progesterone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.	got7fsn_ti							mah	2009-12-11T04:11:13Z						biological_process											owl:Class	
GO:1904740	biolink:NamedThing	obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter	OBSOLETE. A transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation.	got7fsn_ti	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by RNA polymerase II transcription factor activity|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by general transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by gene-specific transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		tb	2015-10-15T21:30:51Z		True				biological_process											owl:Class	
GO:1903912	biolink:NamedThing	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation.	got7fsn_ti	downregulation of eiF2alpha phosphorylation in response to ER stress|down-regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of ER stress-induced eIF2 alpha phosphorylation|down regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|inhibition of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down-regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|inhibition of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down regulation of eiF2alpha phosphorylation in response to ER stress|downregulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of eiF2alpha phosphorylation in response to ER stress|negative regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|inhibition of eiF2alpha phosphorylation in response to ER stress|downregulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down-regulation of eiF2alpha phosphorylation in response to ER stress						bf	2015-02-09T10:58:55Z						biological_process											owl:Class	
GO:0052113	biolink:NamedThing	obsolete adaptation to host osmotic environment	OBSOLETE. The responsive adjustment of an organism to the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	osmotic tolerance to host environment|adaptation to host osmotic environment				This term was made obsolete because adaptation was not deemed to be a valid biological process.					True				biological_process											owl:Class	
GO:0006747	biolink:NamedThing	FAD biosynthetic process	The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide.	got7fsn_ti	oxidized flavin-adenine dinucleotide biosynthetic process|oxidized flavin adenine dinucleotide biosynthesis|FAD synthesis|FAD formation|oxidized flavin-adenine dinucleotide biosynthesis|oxidized flavin adenine dinucleotide biosynthetic process|FAD anabolism|FAD biosynthesis													biological_process											owl:Class	
CHEBI:61293	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000886	biolink:NamedThing	glucuronoxylan catabolic process	The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan.	got7fsn_ti	glucuronoxylan catabolism						jl	2011-07-28T09:37:06Z						biological_process											owl:Class	
GO:1901960	biolink:NamedThing	isobutanol metabolic process	The chemical reactions and pathways involving isobutanol.	got7fsn_ti	isobutanol metabolism						tt	2013-02-19T21:49:44Z						biological_process											owl:Class	
GO:0046135	biolink:NamedThing	pyrimidine nucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	got7fsn_ti	pyrimidine nucleoside breakdown|pyrimidine nucleoside catabolism|pyrimidine nucleoside degradation													biological_process											owl:Class	
GO:0044127	biolink:NamedThing	regulation of development of symbiont in host	Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti					This term partially replaces the obsolete term 'regulation of growth or development of symbiont in host ; GO:0033665'. See also 'regulation of growth of symbiont in host ; GO:0044126'.		jl	2009-08-04T02:11:08Z						biological_process											owl:Class	
GO:0032012	biolink:NamedThing	regulation of ARF protein signal transduction	Any process that modulates the frequency, rate or extent of ARF protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:1901738	biolink:NamedThing	regulation of vitamin A metabolic process	Any process that modulates the frequency, rate or extent of vitamin A metabolic process.	got7fsn_ti	regulation of vitamin A metabolism						dph	2013-01-11T15:29:43Z						biological_process											owl:Class	
GO:1904034	biolink:NamedThing	positive regulation of t-SNARE clustering	Any process that activates or increases the frequency, rate or extent of t-SNARE clustering.	got7fsn_ti	up regulation of t-SNARE clustering|activation of t-SNARE clustering|up-regulation of t-SNARE clustering|upregulation of t-SNARE clustering						sl	2015-03-13T21:21:50Z						biological_process											owl:Class	
GO:0019078	biolink:NamedThing	obsolete lytic viral budding	OBSOLETE. A form of viral release in which the viral particles bud out through cellular membranes, resulting in cell lysis. It is also a form of viral envelopment.	got7fsn_ti	lytic viral budding				This term was made obsolete because it does not appear to correspond to a real biological process.					True				biological_process											owl:Class	
GO:2000323	biolink:NamedThing	negative regulation of glucocorticoid receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.	got7fsn_ti	negative regulation of glucocorticoid receptor signalling pathway						vk	2011-01-18T04:38:43Z						biological_process											owl:Class	
GO:0070131	biolink:NamedThing	positive regulation of mitochondrial translation	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.	got7fsn_ti	positive regulation of mitochondrial protein biosynthesis|positive regulation of mitochondrial protein formation|positive regulation of mitochondrial protein anabolism|positive regulation of mitochondrial protein synthesis													biological_process											owl:Class	
GO:0034169	biolink:NamedThing	positive regulation of toll-like receptor 10 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway.	got7fsn_ti	positive regulation of toll-like receptor 10 signalling pathway|positive regulation of TLR10 signaling pathway													biological_process											owl:Class	
GO:0005352	biolink:NamedThing	alpha-glucoside:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose.	got7fsn_ti	general alpha-glucoside transporter activity|general alpha-glucoside:hydrogen symporter activity|general alpha-glucoside:proton symporter activity|alpha-glucoside:hydrogen symporter activity													molecular_function											owl:Class	
GO:0033126	biolink:NamedThing	obsolete positive regulation of GTP catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.	got7fsn_ti	positive regulation of GTP breakdown|positive regulation of GTP degradation|positive regulation of GTP catabolism				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0043547				True				biological_process											owl:Class	
GO:1902309	biolink:NamedThing	negative regulation of peptidyl-serine dephosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation.	got7fsn_ti	down regulation of peptidyl-serine dephosphorylation|downregulation of peptidyl-serine dephosphorylation|down-regulation of peptidyl-serine dephosphorylation|inhibition of peptidyl-serine dephosphorylation						rl	2013-07-19T10:35:07Z						biological_process											owl:Class	
GO:0005276	biolink:NamedThing	obsolete vesicular amino acid:proton antiporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a vesicle membrane to the other according to the reaction: H+(in) + amino acid(out) = H+(out) + amino acid(in).	got7fsn_ti	vesicular hydrogen:amino acid antiporter activity|hydrogen:vesicular amine antiporter activity				The reason for obsoletion is that the cellular component does not belong is the MF according to the documentation: http://wiki.geneontology.org/index.php/Transporter_terms_standard_definitions					True				molecular_function											owl:Class	
GO:0006784	biolink:NamedThing	heme A biosynthetic process	The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3.	got7fsn_ti	heme A formation|haem A biosynthesis|heme A synthesis|heme A biosynthesis|heme A anabolism|haem A biosynthetic process													biological_process											owl:Class	
GO:0042448	biolink:NamedThing	progesterone metabolic process	The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.	got7fsn_ti	progesterone metabolism													biological_process											owl:Class	
GO:0052180	biolink:NamedThing	obsolete negative regulation of peptidase activity in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	down regulation of protease activity in other organism during symbiotic interaction|down-regulation of protease activity in other organism during symbiotic interaction|negative regulation of protease activity in other organism during symbiotic interaction|inhibition of protease activity in other organism during symbiotic interaction|downregulation of protease activity in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0070759	biolink:NamedThing	negative regulation of interleukin-35-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.	got7fsn_ti	negative regulation of interleukin-35-mediated signalling pathway|negative regulation of IL-35-mediated signaling pathway						mah	2009-06-23T02:02:07Z						biological_process											owl:Class	
GO:1900828	biolink:NamedThing	D-tyrosine metabolic process	The chemical reactions and pathways involving D-tyrosine.	got7fsn_ti	D-tyrosine metabolism						se	2012-06-06T09:27:00Z						biological_process											owl:Class	
GO:2000546	biolink:NamedThing	positive regulation of endothelial cell chemotaxis to fibroblast growth factor	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.	got7fsn_ti							ebc	2011-04-03T07:17:27Z						biological_process											owl:Class	
GO:0062112	biolink:NamedThing	fatty acid primary amide biosynthetic process	The chemical reactions and pathways resulting in the formation of a fatty acid primary amide.	got7fsn_ti	fatty acid amide biosynthesis|FAPA biosynthesis|FAPA biosynthetic process						dph	2019-02-20T12:49:43Z						biological_process											owl:Class	
GO:0018919	biolink:NamedThing	gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.	got7fsn_ti	gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolism											UM-BBD_pathwayID:ghch|MetaCyc:GAMMAHEXCHLORDEG-PWY		biological_process											owl:Class	
GO:0052457	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont nitric oxide production	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont NO production|modulation by organism of defense-related symbiont nitric oxide production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1903506	biolink:NamedThing	regulation of nucleic acid-templated transcription	Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.	got7fsn_ti							pr	2014-10-01T14:44:47Z						biological_process											owl:Class	
GO:0035834	biolink:NamedThing	indole alkaloid metabolic process	The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.	got7fsn_ti	indole alkaloid metabolism						bf	2011-05-04T03:17:44Z						biological_process											owl:Class	
GO:0051141	biolink:NamedThing	negative regulation of NK T cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.	got7fsn_ti	negative regulation of NKT cell proliferation|negative regulation of NK T lymphocyte proliferation|down regulation of NK T cell proliferation|inhibition of NK T cell proliferation|downregulation of NK T cell proliferation|negative regulation of NK T-cell proliferation|down-regulation of NK T cell proliferation|negative regulation of NT cell proliferation|negative regulation of NK T-lymphocyte proliferation|negative regulation of natural killer T cell proliferation|negative regulation of natural T cell proliferation													biological_process											owl:Class	
GO:0005190	biolink:NamedThing	obsolete seminal fluid protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	seminal fluid protein				This term was made obsolete because it describes presence in body fluids rather than an activity.					True				molecular_function											owl:Class	
CHEBI:58083	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902156	biolink:NamedThing	positive regulation of response to G1 DNA damage checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.	got7fsn_ti	up-regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|upregulation of response to G1 DNA damage checkpoint signaling|up-regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|activation of response to G1 DNA damage checkpoint signaling|activation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|up regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|upregulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|positive regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|upregulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|positive regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|upregulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|activation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|up-regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|up-regulation of response to G1 DNA damage checkpoint signaling|activation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|up regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|positive regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up regulation of response to G1 DNA damage checkpoint signaling						jl	2013-05-21T15:44:58Z						biological_process											owl:Class	
GO:0150033	biolink:NamedThing	negative regulation of protein localization to lysosome	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.	got7fsn_ti							bc	2018-02-06T17:14:16Z						biological_process											owl:Class	
GO:0019638	biolink:NamedThing	6-hydroxycineole metabolic process	The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.	got7fsn_ti	6-endo-hydroxycineole metabolic process|6-endo-hydroxycineole metabolism|hydroxycineol metabolic process|hydroxycineol metabolism|6-hydroxycineole metabolism													biological_process											owl:Class	
CHEBI:28817	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000335	biolink:NamedThing	regulation of endothelial microparticle formation	Any process that modulates the frequency, rate or extent of endothelial microparticle formation.	got7fsn_ti	regulation of endothelial microparticle generation|regulation of endothelial microparticle release						mah	2011-01-31T11:20:26Z						biological_process											owl:Class	
GO:0038068	biolink:NamedThing	obsolete MAP kinase kinase activity involved in cell wall organization or biogenesis	OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.	got7fsn_ti	MAP kinase kinase activity involved in cell wall biogenesis|MAP2K activity involved in cell wall integrity|MAPKK activity involved in cell wall integrity				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-25T03:34:10Z		True				molecular_function											owl:Class	
GO:1900281	biolink:NamedThing	positive regulation of CD4-positive, alpha-beta T cell costimulation	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.	got7fsn_ti	upregulation of CD4-positive, alpha beta T cell costimulation|positive regulation of CD4-positive, alpha beta T cell costimulation|up-regulation of CD4-positive, alpha beta T cell costimulation|activation of CD4-positive, alpha beta T cell costimulation|up regulation of CD4-positive, alpha beta T cell costimulation						rl	2012-04-04T08:56:45Z						biological_process											owl:Class	
GO:0051497	biolink:NamedThing	negative regulation of stress fiber assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.	got7fsn_ti	negative regulation of stress fibre formation|down-regulation of stress fiber formation|inhibition of stress fiber formation|downregulation of stress fiber formation|negative regulation of stress fibre biosynthesis|down regulation of stress fiber formation													biological_process											owl:Class	
GO:0044120	biolink:NamedThing	obsolete development of symbiont in host vacuole	OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring in a host vacuole. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	development of symbiont in host organelle	https://github.com/geneontology/go-ontology/issues/20305			This term was obsoleted because it represents both a process and a location.		jl	2009-07-30T03:59:54Z		True				biological_process											owl:Class	
GO:1901832	biolink:NamedThing	all-trans-neoxanthin catabolic process	The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin.	got7fsn_ti	all-trans-neoxanthin breakdown|neoxanthin catabolic process|all-trans-neoxanthin catabolism|neoxanthin catabolism|neoxanthin degradation|neoxanthin breakdown|all-trans-neoxanthin degradation						yaf	2013-01-22T12:43:51Z						biological_process											owl:Class	
GO:1905061	biolink:NamedThing	negative regulation of cardioblast proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation.	got7fsn_ti	downregulation of cardioblast proliferation|down regulation of cardioblast proliferation|down-regulation of cardioblast proliferation|inhibition of cardioblast proliferation						bc	2016-03-21T11:00:13Z						biological_process											owl:Class	
GO:0019027	biolink:NamedThing	obsolete ambisense viral genome	OBSOLETE. A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:0045640	biolink:NamedThing	regulation of basophil differentiation	Any process that modulates the frequency, rate or extent of basophil differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1901231	biolink:NamedThing	positive regulation of non-canonical Wnt signaling pathway via JNK cascade	Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.	got7fsn_ti	upregulation of non-canonical Wnt receptor signaling pathway via JNK cascade|up-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|up regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|positive regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|up regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|positive regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|activation of non-canonical Wnt receptor signalling pathway via JNK cascade|up-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|upregulation of non-canonical Wnt receptor signalling pathway via JNK cascade|activation of non-canonical Wnt receptor signaling pathway via JNK cascade|positive regulation of non-canonical Wnt receptor signaling pathway via JNK cascade						vk	2012-08-07T14:14:48Z						biological_process											owl:Class	
GO:0044049	biolink:NamedThing	obsolete interaction with host via protein secreted by type VI secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type VI secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
CHEBI:57977	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060865	biolink:NamedThing	negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway	The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission.	got7fsn_ti	negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signalling pathway						dph	2009-08-12T04:42:14Z						biological_process											owl:Class	
GO:0045797	biolink:NamedThing	positive regulation of intestinal cholesterol absorption	Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.	got7fsn_ti	activation of cholesterol absorption|upregulation of cholesterol absorption|up regulation of cholesterol absorption|stimulation of cholesterol absorption|up-regulation of cholesterol absorption													biological_process											owl:Class	
GO:0052384	biolink:NamedThing	obsolete evasion or tolerance by organism of symbiont-produced reactive oxygen species	OBSOLETE. The process by which an organism avoids the effects of reactive oxygen species produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	evasion or tolerance of symbiont-produced AOS|evasion by organism of cellular damage caused by symbiont oxidative burst|evasion or tolerance of defense-related symbiont respiratory burst|evasion or tolerance of reactive oxygen species produced by symbiont in response to organism|evasion or tolerance of defense-related symbiont oxidative burst|evasion or tolerance by organism of symbiont-produced reactive oxygen species|evasion or tolerance by organism of reactive oxygen species produced during symbiont defense response|evasion or tolerance of symbiont-produced ROS|evasion or tolerance of symbiont-produced active oxygen species|evasion or tolerance of symbiont-produced ROIs|evasion or tolerance of defense-related symbiont metabolic burst|evasion or tolerance of symbiont-produced reactive oxygen intermediates				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0002786	biolink:NamedThing	regulation of antibacterial peptide production	Any process that modulates the frequency, rate, or extent of antibacterial peptide production.	got7fsn_ti														biological_process											owl:Class	
GO:0075012	biolink:NamedThing	negative regulation of germ tube formation	Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of germ tube formation on or near host													biological_process											owl:Class	
GO:1900965	biolink:NamedThing	regulation of methanophenazine metabolic process	Any process that modulates the frequency, rate or extent of methanophenazine metabolic process.	got7fsn_ti	regulation of methanophenazine metabolism						tt	2012-06-14T03:55:26Z						biological_process											owl:Class	
GO:0052217	biolink:NamedThing	obsolete aerotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	aerotaxis in response to environment of other organism|aerotaxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0051588	biolink:NamedThing	regulation of neurotransmitter transport	Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0045808	biolink:NamedThing	negative regulation of establishment of competence for transformation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation.	got7fsn_ti	inhibitor of the establishment of competence for transformation activity|inhibition of establishment of competence for transformation|down-regulation of establishment of competence for transformation|down regulation of establishment of competence for transformation|downregulation of establishment of competence for transformation													biological_process											owl:Class	
GO:0099552	biolink:NamedThing	trans-synaptic signaling by lipid, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
GO:0061015	biolink:NamedThing	snRNA import into nucleus	The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus.	got7fsn_ti							dph	2010-01-29T02:36:00Z						biological_process											owl:Class	
CHEBI:22916	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902975	biolink:NamedThing	mitotic DNA replication initiation	Any DNA replication initiation involved in mitotic cell cycle DNA replication.	got7fsn_ti	DNA replication initiation involved in mitotic cell cycle DNA replication						jl	2014-05-06T15:21:11Z						biological_process											owl:Class	
GO:0016565	biolink:NamedThing	obsolete general transcriptional repressor activity	OBSOLETE. Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set.	got7fsn_ti	general transcriptional repressor activity				This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001227|GO:0001217|GO:0045892				True				molecular_function											owl:Class	
GO:1902349	biolink:NamedThing	response to chloroquine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.	got7fsn_ti							kmv	2013-08-13T19:29:25Z						biological_process											owl:Class	
CHEBI:57504	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018900	biolink:NamedThing	dichloromethane metabolic process	The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover.	got7fsn_ti	dichloromethane metabolism											UM-BBD_pathwayID:dcm		biological_process											owl:Class	
GO:0070173	biolink:NamedThing	regulation of enamel mineralization	Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.	got7fsn_ti														biological_process											owl:Class	
GO:0003792	biolink:NamedThing	obsolete regulation of actin thin filament length activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	regulation of actin thin filament length activity			GO:0030832	This term was made obsolete because the term belongs in the process ontology.					True				molecular_function											owl:Class	
GO:1903145	biolink:NamedThing	actin filament of cell cortex of cell tip	Any actin filament that is part of a cell cortex of cell tip.	got7fsn_ti	actin filament of cell cortex of cell end|microfilament of cell cortex of cell end|microfilament of cell cortex of cell tip						vw	2014-07-06T16:24:01Z						cellular_component											owl:Class	
GO:1901005	biolink:NamedThing	ubiquinone-6 catabolic process	The chemical reactions and pathways resulting in the breakdown of ubiquinone-6.	got7fsn_ti	ubiquinone-6 breakdown|ubiquinone-6 degradation|ubiquinone-6 catabolism						bf	2012-06-15T09:59:51Z						biological_process											owl:Class	
GO:0070609	biolink:NamedThing	regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.	got7fsn_ti	regulation of ascospore wall 1,3-alpha-glucan metabolism|regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process|regulation of ascospore wall alpha-1,3 glucan metabolism|regulation of ascospore wall alpha-1,3 glucan metabolic process						mah	2009-04-29T01:29:02Z						biological_process											owl:Class	
GO:1900296	biolink:NamedThing	positive regulation of heptasaccharide transport	Any process that activates or increases the frequency, rate or extent of heptasaccharide transport.	got7fsn_ti	upregulation of heptasaccharide transport|up regulation of heptasaccharide transport|up-regulation of heptasaccharide transport|activation of heptasaccharide transport						tt	2012-04-05T07:40:58Z						biological_process											owl:Class	
GO:0015967	biolink:NamedThing	diadenosine tetraphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.	got7fsn_ti	diadenosine tetraphosphate catabolism|diadenosine tetraphosphate degradation|diadenosine tetraphosphate breakdown													biological_process											owl:Class	
GO:0006556	biolink:NamedThing	S-adenosylmethionine biosynthetic process	The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.	got7fsn_ti	S-adenosyl methionine biosynthetic process|S-adenosylmethionine biosynthesis|S-adenosylmethionine synthesis|SAM biosynthetic process|S-adenosylmethionine formation|S-adenosylmethionine anabolism|S-adenosyl methionine biosynthesis											MetaCyc:SAM-PWY		biological_process											owl:Class	
GO:0015597	biolink:NamedThing	obsolete histidine/arginine/lysine/ornithine porter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).	got7fsn_ti	histidine/arginine/lysine/ornithine porter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0000064|GO:0015181|GO:0015426|GO:0015189|GO:0005290				True				molecular_function											owl:Class	
GO:1902269	biolink:NamedThing	positive regulation of polyamine transmembrane transport	Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.	got7fsn_ti	up-regulation of polyamine transmembrane transport|up regulation of polyamine transmembrane transport|activation of polyamine transmembrane transport|upregulation of polyamine transmembrane transport						mcc	2013-06-28T21:34:47Z						biological_process											owl:Class	
GO:0062054	biolink:NamedThing	fluoride channel activity	Enables the facilitated diffusion of fluoride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti							dph	2018-06-25T13:30:23Z						molecular_function											owl:Class	
GO:1902792	biolink:NamedThing	pyrroline-5-carboxylate reductase complex	A protein complex which is capable of pyrroline-5-carboxylate reductase activity.	got7fsn_ti					An example of this is PYCR1 in human (P32322) in PMID:2722838 (inferred from direct assay).		bhm	2014-03-24T09:55:22Z						cellular_component											owl:Class	
GO:0032423	biolink:NamedThing	regulation of mismatch repair	Any process that modulates the frequency, rate or extent of mismatch repair.	got7fsn_ti														biological_process											owl:Class	
GO:0018889	biolink:NamedThing	2-chloro-N-isopropylacetanilide metabolic process	The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.	got7fsn_ti	propachlor metabolic process|2-chloro-N-isopropylacetanilide metabolism|propachlor metabolism											UM-BBD_pathwayID:ppc		biological_process											owl:Class	
GO:0052653	biolink:NamedThing	3',5'-cyclic diguanylic acid metabolic process	The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine.	got7fsn_ti	3',5'-cyclic diguanylic acid metabolism|cdiGMP metabolic process|cyclic diguanylate metabolic process|cyclic diguanylate metabolism|cdiGMP metabolism						ai	2010-09-23T11:16:56Z						biological_process											owl:Class	
GO:1905646	biolink:NamedThing	positive regulation of FACT complex assembly	Any process that activates or increases the frequency, rate or extent of FACT complex assembly.	got7fsn_ti	up-regulation of FACT complex assembly|up-regulation of FACT complex formation|positive regulation of Facilitates chromatin transcription complex assembly|up regulation of Facilitates chromatin transcription complex formation|up regulation of FACT complex assembly|activation of Facilitates chromatin transcription complex assembly|upregulation of Facilitates chromatin transcription complex assembly|activation of Facilitates chromatin transcription complex formation|up-regulation of Facilitates chromatin transcription complex assembly|upregulation of FACT complex formation|upregulation of Facilitates chromatin transcription complex formation|positive regulation of Facilitates chromatin transcription complex formation|activation of FACT complex assembly|upregulation of FACT complex assembly|up regulation of FACT complex formation|positive regulation of FACT complex formation|up-regulation of Facilitates chromatin transcription complex formation|activation of FACT complex formation|up regulation of Facilitates chromatin transcription complex assembly						pga	2016-11-07T09:14:21Z						biological_process											owl:Class	
GO:1903527	biolink:NamedThing	positive regulation of membrane tubulation	Any process that activates or increases the frequency, rate or extent of membrane tubulation.	got7fsn_ti	upregulation of membrane tubulation|up-regulation of plasma membrane tubulation|activation of plasma membrane tubulation|positive regulation of plasma membrane tubulation|activation of membrane tubulation|up-regulation of membrane tubulation|upregulation of plasma membrane tubulation|up regulation of membrane tubulation|up regulation of plasma membrane tubulation						pm	2014-10-07T12:52:53Z						biological_process											owl:Class	
GO:0030535	biolink:NamedThing	obsolete adult feeding behavior (sensu Insecta)	OBSOLETE. Feeding behavior in a fully developed and mature organism, as described in insects.	got7fsn_ti	adult feeding behavior (sensu Insecta)			GO:0008343	This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.					True				biological_process											owl:Class	
GO:1903929	biolink:NamedThing	primary palate development	The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure.	got7fsn_ti	primitive palate development|processus palatinus medianus development|palatum primarium development|primary palate process development						cls	2015-02-11T22:42:38Z						biological_process											owl:Class	
GO:0002668	biolink:NamedThing	negative regulation of T cell anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.	got7fsn_ti	negative regulation of T-lymphocyte anergy|negative regulation of T lymphocyte anergy|negative regulation of T-cell anergy|inhibition of T cell anergy|down regulation of T cell anergy|down-regulation of T cell anergy|downregulation of T cell anergy													biological_process											owl:Class	
GO:0008981	biolink:NamedThing	obsolete protease IV activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	protease IV activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0006340	biolink:NamedThing	obsolete negative regulation of transcription of homeotic gene (Polycomb group)	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the Polycomb group.	got7fsn_ti	negative regulation of transcription of homeotic gene (Polycomb group)				This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0000122|GO:0048096|GO:0031507				True				biological_process											owl:Class	
GO:1900997	biolink:NamedThing	benzene biosynthetic process	The chemical reactions and pathways resulting in the formation of benzene.	got7fsn_ti	benzene formation|benzene synthesis|benzene anabolism|benzene biosynthesis						yaf	2012-06-14T02:54:01Z						biological_process											owl:Class	
GO:0034490	biolink:NamedThing	basic amino acid transmembrane import into vacuole	The directed movement of basic amino acids into the vacuole across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0150144	biolink:NamedThing	negative regulation of CD80 production	Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process.	got7fsn_ti	negative regulation of CD80 biosynthetic process						bc	2019-12-08T10:26:42Z						biological_process											owl:Class	
GO:1902719	biolink:NamedThing	obsolete extracellular sequestering of copper ion	OBSOLETE. The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system.	got7fsn_ti	extracellular sequestering of copper ion				This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2014-02-24T16:09:09Z		True				biological_process											owl:Class	
GO:0090363	biolink:NamedThing	regulation of proteasome core complex assembly	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.	got7fsn_ti							tb	2010-07-12T10:48:57Z						biological_process											owl:Class	
GO:0070426	biolink:NamedThing	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.	got7fsn_ti	positive regulation of nucleotide-binding oligomerization domain containing signalling pathway|positive regulation of NOD signaling pathway													biological_process											owl:Class	
GO:1903258	biolink:NamedThing	sorbose import across plasma membrane	The process in which sorbose is transported from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	sorbose import into cell						mah	2014-08-06T09:21:53Z						biological_process											owl:Class	
GO:1904089	biolink:NamedThing	negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of neuron apoptotic process.	got7fsn_ti	negative regulation of neuron apoptosis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of programmed cell death, neurons by negative regulation of transcription from RNA polymerase II promoter						pr	2015-03-25T21:04:51Z						biological_process											owl:Class	
GO:0046382	biolink:NamedThing	GDP-D-rhamnose metabolic process	The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-D-rhamnose metabolism													biological_process											owl:Class	
CHEBI:33696	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050995	biolink:NamedThing	negative regulation of lipid catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.	got7fsn_ti	negative regulation of lipid catabolism|downregulation of lipid catabolic process|negative regulation of lipid degradation|down-regulation of lipid catabolic process|down regulation of lipid catabolic process|negative regulation of lipid breakdown|inhibition of lipid catabolic process													biological_process											owl:Class	
GO:1901836	biolink:NamedThing	regulation of transcription of nucleolar large rRNA by RNA polymerase I	Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.	got7fsn_ti	regulation of transcription of nuclear rRNA large Pol I transcript|regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter						sart	2013-01-23T10:16:27Z						biological_process											owl:Class	
GO:0046049	biolink:NamedThing	UMP metabolic process	The chemical reactions and pathways involving UMP, uridine monophosphate.	got7fsn_ti	UMP metabolism													biological_process											owl:Class	
GO:0032084	biolink:NamedThing	regulation of type I site-specific deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity.	got7fsn_ti	type I restriction enzyme regulator|regulation of type I restriction endodeoxyribonuclease activity|type I restriction endodeoxyribonuclease regulator													biological_process											owl:Class	
GO:0045427	biolink:NamedThing	obsolete enzyme active site formation via (phospho-5'-guanosine)-L-histidine	OBSOLETE. The transient guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:10529169.	GO:0036428				True				biological_process											owl:Class	
CL:0000716	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034159	biolink:NamedThing	regulation of toll-like receptor 8 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 8 signalling pathway|regulation of TLR8 signaling pathway													biological_process											owl:Class	
GO:0006328	biolink:NamedThing	obsolete AT binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	AT binding			GO:0003680	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:2001010	biolink:NamedThing	negative regulation of plant-type cell wall cellulose biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.	got7fsn_ti	negative regulation of cellulose biosynthesis during cell wall biosynthesis|negative regulation of cell wall cellulose biosynthesis						tt	2011-08-08T08:47:22Z						biological_process											owl:Class	
CHEBI:57488	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001016	biolink:NamedThing	positive regulation of skeletal muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.	got7fsn_ti							yaf	2011-08-11T08:54:44Z						biological_process											owl:Class	
GO:1900440	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.	got7fsn_ti							di	2012-04-25T05:55:48Z						biological_process											owl:Class	
GO:0048114	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010549	biolink:NamedThing	regulation of membrane disassembly	Any process that modulates the frequency, rate or extent of membrane disassembly.	got7fsn_ti														biological_process											owl:Class	
GO:0071399	biolink:NamedThing	cellular response to linoleic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.	got7fsn_ti	cellular response to linoleate						mah	2009-12-11T04:40:22Z						biological_process											owl:Class	
GO:0120042	biolink:NamedThing	negative regulation of macrophage proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation.	got7fsn_ti							krc	2017-05-10T20:51:40Z						biological_process											owl:Class	
GO:0016962	biolink:NamedThing	obsolete receptor-associated protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	receptor-associated protein activity				This term was made obsolete because it describes a gene product and not a molecular function.	GO:0005515|GO:0005102				True				molecular_function											owl:Class	
GO:1902085	biolink:NamedThing	fumagillin catabolic process	The chemical reactions and pathways resulting in the breakdown of fumagillin.	got7fsn_ti	fumagillin degradation|fumagillin catabolism|fumagillin breakdown						di	2013-04-25T14:00:45Z						biological_process											owl:Class	
GO:0015519	biolink:NamedThing	D-xylose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in).	got7fsn_ti	D-xylose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0030405	biolink:NamedThing	obsolete matrix metalloproteinase 19 activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	matrix metalloproteinase 19 activity|MMP-19			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:62436	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901949	biolink:NamedThing	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.	got7fsn_ti	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthesis|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate synthesis|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate anabolism|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate formation						ms	2013-02-18T15:50:50Z						biological_process											owl:Class	
GO:0045855	biolink:NamedThing	negative regulation of pole plasm oskar mRNA localization	Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.	got7fsn_ti	inhibition of pole plasm oskar mRNA localization|negative regulation of oocyte pole plasm oskar mRNA localization|negative regulation of pole plasm oskar mRNA localisation|down-regulation of pole plasm oskar mRNA localization|down regulation of pole plasm oskar mRNA localization|downregulation of pole plasm oskar mRNA localization													biological_process											owl:Class	
GO:1990544	biolink:NamedThing	mitochondrial ATP transmembrane transport	The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T11:43:33Z						biological_process											owl:Class	
GO:1904631	biolink:NamedThing	response to glucoside	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.	got7fsn_ti	response to glucosides						sl	2015-08-28T14:01:31Z						biological_process											owl:Class	
GO:0032696	biolink:NamedThing	negative regulation of interleukin-13 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production.	got7fsn_ti	down-regulation of interleukin-13 production|negative regulation of interleukin-13 biosynthetic process|negative regulation of IL-13 production|negative regulation of interleukin-13 secretion|downregulation of interleukin-13 production|down regulation of interleukin-13 production|inhibition of interleukin-13 production										GO:0045367|GO:2000666			biological_process											owl:Class	
GO:1990363	biolink:NamedThing	obsolete response to hydrolysate	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of hydrolysate (any product of hydrolysis).	got7fsn_ti	response to hydrolysate				This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:12:24Z		True				biological_process											owl:Class	
GO:0043763	biolink:NamedThing	UTP:glucose-1-phosphate uridylyltransferase regulator activity	Binds to and modulates the activity of UTP:glucose-1-phosphate uridylyltransferase.	got7fsn_ti	glucose-1-phosphate uridylyltransferase regulator activity|UDP-glucose pyrophosphorylase regulator activity|UDP-glucose diphosphorylase regulator activity													molecular_function											owl:Class	
GO:1900226	biolink:NamedThing	negative regulation of NLRP3 inflammasome complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.	got7fsn_ti	down-regulation of NLRP3 inflammasome activation|down-regulation of NLRP3 inflammasome complex assembly|inhibition of NLRP3 inflammasome complex assembly|down regulation of NALP3 inflammasome complex assembly|negative regulation of NLRP3 inflammasome activation|down regulation of NLRP3 inflammasome activation|downregulation of NALP3 inflammasome complex assembly|inhibition of NALP3 inflammasome complex assembly|downregulation of NLRP3 inflammasome complex assembly|inhibition of NLRP3 inflammasome activation|downregulation of NLRP3 inflammasome activation|down-regulation of NALP3 inflammasome complex assembly|down regulation of NLRP3 inflammasome complex assembly|negative regulation of NALP3 inflammasome complex assembly						jl	2012-03-22T04:18:24Z						biological_process											owl:Class	
GO:0052010	biolink:NamedThing	obsolete catabolism by symbiont of host cell wall cellulose	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of host cell wall cellulose	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0150148	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043647	biolink:NamedThing	inositol phosphate metabolic process	The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	got7fsn_ti	myo-inositol phosphate metabolic process|myo-inositol phosphate metabolism|inositol phosphate metabolism													biological_process											owl:Class	
CHEBI:57579	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006945	biolink:NamedThing	obsolete nuclear fusion during karyogamy	OBSOLETE. The fusion of two haploid nuclei to form a single diploid nucleus, as seen in the yeast mating process.	got7fsn_ti	nuclear fusion during karyogamy				This term was made obsolete because it is redundant outside the context of Saccharomyces biology.	GO:0000741				True				biological_process											owl:Class	
GO:1902945	biolink:NamedThing	metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.	got7fsn_ti	metalloendoprotease activity involved in APP catabolic process|metalloendoprotease activity involved in APP catabolism|metalloendopeptidase activity involved in APP catabolic process|metalloendoproteinase activity involved in amyloid precursor protein catabolic process|metalloendopeptidase activity involved in APP catabolism|metalloendoproteinase activity involved in amyloid precursor protein breakdown|metalloendoproteinase activity involved in amyloid precursor protein degradation|metalloendoproteinase activity involved in APP catabolic process|metalloendopeptidase activity involved in amyloid precursor protein catabolism|metalloendoproteinase activity involved in amyloid precursor protein catabolism|metalloendoprotease activity involved in amyloid precursor protein degradation|metalloendoprotease activity involved in amyloid precursor protein catabolic process|metalloendoprotease activity involved in amyloid precursor protein catabolism|metalloendoprotease activity involved in amyloid precursor protein breakdown|metalloendopeptidase activity involved in amyloid precursor protein degradation|metalloendopeptidase activity involved in amyloid precursor protein breakdown|metalloendoproteinase activity involved in APP catabolism						sjp	2014-05-02T08:13:04Z				Reactome:R-HSA-9010034		molecular_function											owl:Class	
CL:0000573	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042904	biolink:NamedThing	9-cis-retinoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative.	got7fsn_ti	9-cis-retinoic acid anabolism|9-cis-retinoic acid biosynthesis|9-cis-retinoic acid formation|9-cis-retinoic acid synthesis													biological_process											owl:Class	
GO:0018879	biolink:NamedThing	biphenyl metabolic process	The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).	got7fsn_ti	xenene metabolism|biphenyl metabolism|xenene metabolic process											UM-BBD_pathwayID:bph		biological_process											owl:Class	
GO:2000271	biolink:NamedThing	positive regulation of fibroblast apoptotic process	Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process.	got7fsn_ti	positive regulation of fibroblast apoptosis						jl	2010-11-23T01:07:29Z						biological_process											owl:Class	
GO:1902757	biolink:NamedThing	bis(molybdopterin guanine dinucleotide)molybdenum metabolic process	The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum.	got7fsn_ti	bis(molybdopterin guanine dinucleotide)molybdenum metabolism						dph	2014-03-06T13:58:10Z						biological_process											owl:Class	
GO:2000699	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.	got7fsn_ti	fibroblast growth factor receptor signaling pathway of ureteric bud formation|FGF receptor signaling pathway of ureteric bud formation|FGF receptor signalling pathway of ureteric bud formation|FGFR signaling pathway of ureteric bud formation|fibroblast growth factor receptor signalling pathway of ureteric bud formation						bf	2011-05-16T04:52:14Z						biological_process											owl:Class	
GO:0033525	biolink:NamedThing	sinapate ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.	got7fsn_ti	sinapate ester biosynthesis|sinapate ester synthesis|sinapate ester formation|sinapate ester anabolism											MetaCyc:PWY-3301		biological_process											owl:Class	
GO:0003077	biolink:NamedThing	obsolete negative regulation of diuresis	OBSOLETE. Any process that reduces the rate of diuresis. Diuresis is the process of renal water excretion.	got7fsn_ti	negative regulation of diuresis				This term was made obsolete because its definition was inaccurate.	GO:0035811				True				biological_process											owl:Class	
GO:0016106	biolink:NamedThing	sesquiterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.	got7fsn_ti	sesquiterpenoid anabolism|sesquiterpenoid synthesis|sesquiterpenoid formation|sesquiterpenoid biosynthesis													biological_process											owl:Class	
GO:1905398	biolink:NamedThing	activated CD4-positive, alpha-beta T cell apoptotic process	Any apoptotic process in an activated CD4-positive, alpha-beta T cell.	got7fsn_ti	activated CD4-positive, alpha-beta T cell apoptosis|activated CD4-positive, alpha-beta T-cell apoptosis|activated CD4-positive, alpha-beta T lymphocyte apoptosis|activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activated CD4-positive, alpha-beta T-cell apoptotic process|activated CD4-positive, alpha-beta T-lymphocyte apoptosis						pga	2016-08-25T08:13:40Z						biological_process											owl:Class	
GO:0046491	biolink:NamedThing	L-methylmalonyl-CoA metabolic process	The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.	got7fsn_ti	L-methylmalonyl-CoA metabolism													biological_process											owl:Class	
GO:0100010	biolink:NamedThing	positive regulation of fever generation by prostaglandin biosynthetic process	Any prostaglandin biosynthetic process process that positively_regulates fever generation.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
PR:000001991	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015443	biolink:NamedThing	obsolete sodium-transporting two-sector ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out).	got7fsn_ti	sodium-transporting two-sector ATPase activity				This term was made obsolete because it refers to a bifunctional gene product.	GO:0046932|GO:0046962				True				molecular_function											owl:Class	
GO:0038080	biolink:NamedThing	obsolete MAP kinase kinase activity involved in osmosensory signaling pathway	OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.	got7fsn_ti	MAP kinase kinase activity involved in osmosensory signalling pathway|MAPKK activity involved in osmosensory signaling pathway|MAP2K activity involved in osmosensory signaling pathway				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:41:31Z		True				molecular_function											owl:Class	
GO:0002686	biolink:NamedThing	negative regulation of leukocyte migration	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.	got7fsn_ti	inhibition of leukocyte migration|negative regulation of immune cell migration|negative regulation of leucocyte migration|downregulation of leukocyte migration|down-regulation of leukocyte migration|down regulation of leukocyte migration													biological_process											owl:Class	
GO:0097482	biolink:NamedThing	muscle cell postsynaptic specialization	A postsynaptic specialization that is part of a neuromuscular junction.	got7fsn_ti	muscle cell postsynaptic density|muscle fiber postsynaptic density						pr	2013-07-02T09:47:40Z						cellular_component											owl:Class	
CHEBI:18107	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0106081	biolink:NamedThing	maltose import across plasma membrane	The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							hjd	2017-12-28T18:14:16Z						biological_process											owl:Class	
GO:0070019	biolink:NamedThing	obsolete transforming growth factor beta type II receptor homodimeric complex	OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers.	got7fsn_ti	TGF-beta type II receptor complex|transforming growth factor beta type II receptor complex|TGF-beta type II receptor dimer|TGFBR2 homodimer	https://github.com/geneontology/go-ontology/issues/12676			This term was made obsolete because it does not represent a physiological complex.					True				cellular_component											owl:Class	
GO:1904988	biolink:NamedThing	negative regulation of endothelial cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation.	got7fsn_ti	down regulation of endothelial cell activation|downregulation of endothelial cell activation|down-regulation of endothelial cell activation|inhibition of endothelial cell activation						bc	2016-02-29T16:16:18Z						biological_process											owl:Class	
GO:0043630	biolink:NamedThing	ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process	The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a non-coding RNA, occurring as part of the process of polyadenylation-dependent non-coding RNA catabolism.	got7fsn_ti	ncRNA polyadenylation during polyadenylation-dependent ncRNA catabolic process|ncRNA polyadenylation involved in poly(A)-dependent ncRNA catabolic process													biological_process											owl:Class	
GO:0003780	biolink:NamedThing	obsolete actin cross-linking activity	OBSOLETE. Interacting selectively with two actin filaments to anchor them together.	got7fsn_ti	actin cross-linking activity				This term was made obsolete because it represents a combination of molecular functions.	GO:0030674|GO:0051015				True				molecular_function											owl:Class	
GO:1901427	biolink:NamedThing	response to propan-1-ol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus.	got7fsn_ti							tt	2012-10-01T18:55:48Z						biological_process											owl:Class	
GO:0008619	biolink:NamedThing	obsolete RHEB small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	RHEB small monomeric GTPase activity			GO:0003924	This term was made obsolete because it represents a gene product.	GO:0001558|GO:0051726				True				molecular_function											owl:Class	
GO:1900887	biolink:NamedThing	regulation of pentadecane biosynthetic process	Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process.	got7fsn_ti	regulation of pentadecane formation|regulation of pentadecane biosynthesis|regulation of pentadecane anabolism|regulation of pentadecane synthesis						tt	2012-06-13T03:03:32Z						biological_process											owl:Class	
GO:0018887	biolink:NamedThing	4-carboxy-4'-sulfoazobenzene metabolic process	The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid.	got7fsn_ti	4-carboxy-4'-sulphoazobenzene metabolic process|4-carboxy-4'-sulfoazobenzene metabolism|4-carboxy-4'-sulphoazobenzene metabolism											UM-BBD_pathwayID:csab		biological_process											owl:Class	
GO:0070960	biolink:NamedThing	positive regulation of neutrophil mediated cytotoxicity	Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.	got7fsn_ti	upregulation of neutrophil mediated cytotoxicity|positive regulation of neutrophil mediated cell killing|up regulation of neutrophil mediated cytotoxicity|activation of neutrophil mediated cytotoxicity|up-regulation of neutrophil mediated cytotoxicity|stimulation of neutrophil mediated cytotoxicity						mah	2009-10-01T02:28:49Z						biological_process											owl:Class	
GO:0052006	biolink:NamedThing	obsolete catabolism by symbiont of substance in host	OBSOLETE. The chemical reactions and pathways performed by an organism in its host resulting in the breakdown of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of substance in host	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0006133	biolink:NamedThing	obsolete 5,10-methylenetetrahydrofolate oxidation	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	5,10-methylenetetrahydrofolate oxidation				This term was made obsolete because it is defined as a function term and is in the process ontology.	GO:0004488|GO:0033738|GO:0004487|GO:0004489				True				biological_process											owl:Class	
GO:0003102	biolink:NamedThing	obsolete positive regulation of diuresis by angiotensin	OBSOLETE. Any process mediated by angiotensin that increases the rate of diuresis.	got7fsn_ti	angiotensin-mediated positive regulation of diuresis|positive regulation of diuresis by angiotensin				This term was made obsolete because the term is misleading.	GO:0035810				True				biological_process											owl:Class	
GO:0000199	biolink:NamedThing	obsolete activation of MAPK activity involved in cell wall organization or biogenesis	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.	got7fsn_ti	activation of MAPK activity involved in cell wall integrity|cell wall biogenesis, activation of MAPK activity|activation of MAPK activity involved in cell wall biogenesis	https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1903217	biolink:NamedThing	negative regulation of protein processing involved in protein targeting to mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion.	got7fsn_ti	negative regulation of mitochondrial protein processing during import|down-regulation of mitochondrial protein processing during import|inhibition of protein processing involved in protein targeting to mitochondrion|inhibition of mitochondrial protein processing during import|down regulation of mitochondrial protein processing during import|down regulation of protein processing involved in protein targeting to mitochondrion|downregulation of protein processing involved in protein targeting to mitochondrion|down-regulation of protein processing involved in protein targeting to mitochondrion|downregulation of mitochondrial protein processing during import						bf	2014-07-24T10:21:00Z						biological_process											owl:Class	
GO:0075240	biolink:NamedThing	regulation of zoospore formation	Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.	got7fsn_ti														biological_process											owl:Class	
GO:0000214	biolink:NamedThing	tRNA-intron endonuclease complex	A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.	got7fsn_ti	SEN complex|tRNA splicing endonuclease complex													cellular_component											owl:Class	
GO:0098940	biolink:NamedThing	anterograde trans-synaptic signaling by nitric oxide	Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide.	got7fsn_ti														biological_process											owl:Class	
GO:0006107	biolink:NamedThing	oxaloacetate metabolic process	The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.	got7fsn_ti	oxaloacetate metabolism													biological_process											owl:Class	
GO:0008451	biolink:NamedThing	obsolete X-Pro aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	got7fsn_ti	aminopeptidase P|X-Pro aminopeptidase activity|aminoacylproline aminopeptidase activity|proline aminopeptidase|Xaa-Pro aminopeptidase activity			GO:0004177	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
OIO:default-namespace	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
GO:1904044	biolink:NamedThing	response to aldosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.	got7fsn_ti							sl	2015-03-16T23:07:53Z						biological_process											owl:Class	
GO:0007353	biolink:NamedThing	obsolete ventral/lateral system	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ventral/lateral system				This term was made obsolete because it does not describe a biological process.	GO:0009880				True				biological_process											owl:Class	
GO:0090367	biolink:NamedThing	negative regulation of mRNA modification	Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.	got7fsn_ti							tb	2010-07-12T11:04:45Z						biological_process											owl:Class	
GO:0015073	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase, class I, regulator activity	OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.	got7fsn_ti	phosphatidylinositol 3-kinase, class I, regulator activity			GO:0046935	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:1901756	biolink:NamedThing	butirosin metabolic process	The chemical reactions and pathways involving butirosin.	got7fsn_ti	butirosin metabolism						yaf	2013-01-14T11:36:18Z						biological_process											owl:Class	
GO:1905563	biolink:NamedThing	negative regulation of vascular endothelial cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.	got7fsn_ti	downregulation of vascular endothelial cell proliferation|down-regulation of vascular endothelial cell proliferation|down regulation of vascular endothelial cell proliferation|inhibition of vascular endothelial cell proliferation						nc	2016-10-17T09:24:26Z						biological_process											owl:Class	
GO:1903434	biolink:NamedThing	negative regulation of constitutive secretory pathway	Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway.	got7fsn_ti	inhibition of constitutive secretory pathway|down-regulation of constitutive secretory pathway|down regulation of constitutive secretory pathway|downregulation of constitutive secretory pathway						als	2014-09-15T15:07:40Z						biological_process											owl:Class	
GO:1902595	biolink:NamedThing	regulation of DNA replication origin binding	Any process that modulates the frequency, rate or extent of DNA replication origin binding.	got7fsn_ti	regulation of ARS binding						mah	2013-12-19T16:19:39Z						biological_process											owl:Class	
GO:0005646	biolink:NamedThing	obsolete importin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	importin|karyopherin				This term was made obsolete because it represents a single gene product and not a complex.	GO:0017056|GO:0005634|GO:0005643|GO:0005737				True				cellular_component											owl:Class	
GO:1904660	biolink:NamedThing	regulation of sensory perception of bitter taste	Any process that modulates the frequency, rate or extent of sensory perception of bitter taste.	got7fsn_ti	regulation of bitter taste perception						mr	2015-09-04T17:54:10Z						biological_process											owl:Class	
GO:0106161	biolink:NamedThing	positive regulation of small RNA loading onto RISC	Any process that activates or increases the frequency, rate or extent of small RNA loading onto RISC.	got7fsn_ti							hjd	2018-11-30T15:45:53Z						biological_process											owl:Class	
GO:0070967	biolink:NamedThing	coenzyme F420 binding	Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.	got7fsn_ti							mah	2009-10-02T11:33:26Z						molecular_function											owl:Class	
GO:0034163	biolink:NamedThing	regulation of toll-like receptor 9 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway.	got7fsn_ti	regulation of TLR9 signaling pathway|regulation of toll-like receptor 9 signalling pathway													biological_process											owl:Class	
GO:0140259	biolink:NamedThing	PRC1 complex binding	Binding to a PRC1 complex.	got7fsn_ti							pg	2018-09-10T16:48:18Z						molecular_function											owl:Class	
GO:2000485	biolink:NamedThing	regulation of glutamine transport	Any process that modulates the frequency, rate or extent of glutamine transport.	got7fsn_ti	regulation of L-glutamine transport						bf	2011-03-11T09:32:23Z						biological_process											owl:Class	
GO:0075097	biolink:NamedThing	obsolete positive regulation by host of symbiont signal transduction mediated by G-protein gamma subunit	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:1902862	biolink:NamedThing	obsolete glycerol catabolic process to glycerone phosphate	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glycerol to glycerone phosphate.	got7fsn_ti	glycerol catabolic process to glycerone phosphate|glycerol breakdown to glycerone phosphate|glycerol catabolism to glycerone phosphate|glycerol degradation to glycerone phosphate				This term was obsoleted at the TermGenie Gatekeeper stage.		dph	2014-04-03T14:42:01Z		True				biological_process											owl:Class	
GO:1904645	biolink:NamedThing	response to amyloid-beta	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.	got7fsn_ti	response to beta-amyloid|response to beta-amyloids						sl	2015-08-31T20:44:43Z						biological_process											owl:Class	
UBERON:0005832	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032226	biolink:NamedThing	positive regulation of synaptic transmission, dopaminergic	Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.	got7fsn_ti	upregulation of synaptic transmission, dopaminergic|up-regulation of synaptic transmission, dopaminergic|up regulation of synaptic transmission, dopaminergic|activation of synaptic transmission, dopaminergic|stimulation of synaptic transmission, dopaminergic													biological_process											owl:Class	
GO:1903960	biolink:NamedThing	negative regulation of anion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport.	got7fsn_ti	downregulation of anion transmembrane transport|down regulation of anion transmembrane transport|inhibition of anion transmembrane transport|down-regulation of anion transmembrane transport						pr	2015-02-25T13:52:35Z						biological_process											owl:Class	
GO:0019478	biolink:NamedThing	D-amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.	got7fsn_ti	D-amino acid breakdown|D-amino acid degradation|D-amino acid catabolism													biological_process											owl:Class	
GO:0072387	biolink:NamedThing	flavin adenine dinucleotide metabolic process	The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.	got7fsn_ti	FAD or FADH2 metabolic process|flavin-adenine dinucleotide metabolic process|flavin adenine dinucleotide metabolism						mah	2010-12-02T04:21:43Z						biological_process											owl:Class	
GO:0006242	biolink:NamedThing	dCTP biosynthetic process	The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate.	got7fsn_ti	dCTP formation|dCTP biosynthesis|dCTP anabolism|dCTP synthesis													biological_process											owl:Class	
GO:0052429	biolink:NamedThing	obsolete modulation by organism of symbiont B-cell mediated immune response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the B-cell mediated immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont B-cell mediated immune response|regulation by organism of symbiont B-cell mediated immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0055130	biolink:NamedThing	D-alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine.	got7fsn_ti	(2R)-2-aminopropanoic acid catabolic process						jid	2009-10-22T02:02:42Z						biological_process											owl:Class	
GO:0099157	biolink:NamedThing	trans-synaptic signalling via exosome	Transynaptic signaling in which the ligand is carried across the synapse by an exosome.	got7fsn_ti	exosome mediated transynaptic signalling						dos	2017-07-05T16:49:44Z						biological_process											owl:Class	
GO:0006708	biolink:NamedThing	ecdysone catabolic process	The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.	got7fsn_ti	ecdysone degradation|ecdysone breakdown|ecdysone catabolism													biological_process											owl:Class	
GO:0004702	biolink:NamedThing	obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	got7fsn_ti	receptor signalling protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity	https://github.com/geneontology/go-ontology/issues/14232			This term was obsoleted because it was not clearly defined.					True		EC:2.7.11.-		molecular_function											owl:Class	
GO:1905149	biolink:NamedThing	positive regulation of smooth muscle hypertrophy	Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy.	got7fsn_ti	upregulation of smooth muscle hypertrophy|activation of smooth muscle hypertrophy|up regulation of smooth muscle hypertrophy|up-regulation of smooth muscle hypertrophy						bc	2016-04-15T12:47:24Z						biological_process											owl:Class	
GO:1904060	biolink:NamedThing	negative regulation of locomotor rhythm	Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm.	got7fsn_ti	down-regulation of locomotor rhythm|down regulation of circadian locomotor activity rhythm|inhibition of circadian locomotor activity rhythm|downregulation of locomotor rhythm|down-regulation of circadian locomotor activity rhythm|down regulation of locomotor rhythm|downregulation of circadian locomotor activity rhythm|inhibition of locomotor rhythm|negative regulation of circadian locomotor activity rhythm						sl	2015-03-18T20:38:58Z						biological_process											owl:Class	
GO:0010898	biolink:NamedThing	positive regulation of triglyceride catabolic process	Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.	got7fsn_ti	positive regulation of triacylglycerol catabolic process													biological_process											owl:Class	
GO:0052343	biolink:NamedThing	obsolete positive regulation by organism of symbiont phytoalexin production	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of symbiont phytoalexin production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0009872	biolink:NamedThing	obsolete gametophytic self-incompatibility	OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place.	got7fsn_ti	gametophytic self-incompatibility				This term was made obsolete because it represents a phenotype.					True				biological_process											owl:Class	
GO:0052476	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway|suppression by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway				This term was made obsolete because it does not represent a valid biological process that occurs in nature.					True				biological_process											owl:Class	
GO:0019360	biolink:NamedThing	nicotinamide nucleotide biosynthetic process from niacinamide	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide.	got7fsn_ti	nicotinamide nucleotide anabolism from niacinamide|nicotinamide nucleotide formation from niacinamide|nicotinamide nucleotide synthesis from niacinamide													biological_process											owl:Class	
GO:0140603	biolink:NamedThing	obsolete ATP hydrolysis activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + H+ Pi. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20876		GO:0016887	This term was deprecated because it was created in the wrong branch on the ontology.		pg	2021-02-12T18:57:14Z		True				molecular_function											owl:Class	
GO:0075335	biolink:NamedThing	obsolete positive regulation of symbiont adenylate cyclase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0006063	biolink:NamedThing	uronic acid metabolic process	The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.	got7fsn_ti	uronic acid metabolism													biological_process											owl:Class	
GO:1902801	biolink:NamedThing	regulation of heterochromatin island assembly	Any process that modulates the frequency, rate or extent of heterochromatin island assembly.	got7fsn_ti	regulation of heterochromatin island formation						mah	2014-03-25T14:44:48Z						biological_process											owl:Class	
GO:0046458	biolink:NamedThing	hexadecanal metabolic process	The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.	got7fsn_ti	hexadecanal metabolism													biological_process											owl:Class	
GO:0051570	biolink:NamedThing	regulation of histone H3-K9 methylation	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.	got7fsn_ti														biological_process											owl:Class	
CHEBI:64531	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052481	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|negative modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|negative modulation by organism of defense-related symbiont SA-mediated signal transduction pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
CHEBI:17263	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048076	biolink:NamedThing	regulation of compound eye pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.	got7fsn_ti														biological_process											owl:Class	
GO:0032372	biolink:NamedThing	negative regulation of sterol transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	inhibition of sterol transport|down-regulation of sterol transport|downregulation of sterol transport|down regulation of sterol transport													biological_process											owl:Class	
GO:0039581	biolink:NamedThing	obsolete suppression by virus of host PKR activity via double-stranded RNA binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by binding to double-stranded RNA (dsRNA). Binding of viral proteins to RNA may sequester or alter the RNA so it can not be recognized by host PKR, or may compete with PKR for dsRNA binding.	got7fsn_ti	suppression by virus of host PKR activity by binding to dsRNA				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True				biological_process											owl:Class	
GO:0019673	biolink:NamedThing	GDP-mannose metabolic process	The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-mannose metabolism													biological_process											owl:Class	
GO:1902566	biolink:NamedThing	regulation of eosinophil activation	Any process that modulates the frequency, rate or extent of eosinophil activation.	got7fsn_ti							ecu	2013-12-10T15:54:35Z						biological_process											owl:Class	
GO:1903833	biolink:NamedThing	positive regulation of cellular response to amino acid starvation	Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation.	got7fsn_ti	upregulation of cellular response to amino acid starvation|up regulation of cellular response to amino acid starvation|up-regulation of cellular response to amino acid starvation|activation of cellular response to amino acid starvation						rn	2015-01-21T18:44:37Z						biological_process											owl:Class	
GO:1904592	biolink:NamedThing	positive regulation of protein refolding	Any process that activates or increases the frequency, rate or extent of protein refolding.	got7fsn_ti	activation of protein refolding|up-regulation of protein refolding|positive regulation of heat shock protein activity|upregulation of protein refolding|up regulation of heat shock protein activity|up-regulation of heat shock protein activity|upregulation of heat shock protein activity|activation of heat shock protein activity|up regulation of protein refolding						sl	2015-08-21T18:11:16Z						biological_process											owl:Class	
GO:0032708	biolink:NamedThing	negative regulation of interleukin-24 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production.	got7fsn_ti	negative regulation of IL-24 production|negative regulation of interleukin-24 biosynthetic process|down-regulation of interleukin-24 production|downregulation of interleukin-24 production|down regulation of interleukin-24 production|inhibition of interleukin-24 production										GO:0045532			biological_process											owl:Class	
GO:0071534	biolink:NamedThing	obsolete zf-TRAF domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TRAF-type zinc finger (zf-TRAF) domain interaction.	got7fsn_ti	zinc-finger-TRAF domain-mediated complex assembly|TRAF-type zinc finger domain-mediated complex assembly|zinc finger TRAF-type domain-mediated complex assembly				This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T02:40:50Z		True				biological_process											owl:Class	
GO:0008634	biolink:NamedThing	obsolete negative regulation of survival gene product expression	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.	got7fsn_ti	down-regulation of survival gene product activity|downregulation of survival gene product activity|down regulation of survival gene product activity|negative regulation of survival gene product expression|inhibition of survival gene product activity|negative regulation of survival gene product activity|negative regulation of survival gene products				This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc.					True				biological_process											owl:Class	
GO:0090373	biolink:NamedThing	negative regulation of glycerol transport	Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2010-07-12T11:30:22Z						biological_process											owl:Class	
GO:0061917	biolink:NamedThing	leading edge of dendritic growth cone	That part of the dendritic growth cone which represents the distal part of the structure.	got7fsn_ti	distal tip of dendritic growth cone|dendritic growth cone leading edge						dph	2017-07-10T19:25:23Z						cellular_component											owl:Class	
GO:0030210	biolink:NamedThing	heparin biosynthetic process	The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.	got7fsn_ti	heparan sulfate biosynthetic process|heparin biosynthesis|heparin formation|heparin anabolism|heparin synthesis													biological_process											owl:Class	
GO:0016098	biolink:NamedThing	monoterpenoid metabolic process	The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton.	got7fsn_ti	monoterpenoid metabolism													biological_process											owl:Class	
GO:0033903	biolink:NamedThing	obsolete endo-1,3(4)-beta-glucanase activity	OBSOLETE. Catalysis of the endohydrolysis of 1,3- or 1,4-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.	got7fsn_ti	endo-1,4-beta-glucanase activity|beta-1,3-glucanase activity|endo-beta-1,3(4)-glucanase activity|endo-beta-1,3-glucanase IV activity|endo-beta-(1,3)-D-glucanase activity|laminarinase activity|endo-1,3-beta-glucanase activity|endo-1,3-beta-D-glucanase activity|endo-beta-(1->3)-D-glucanase activity|endo-1,3(4)-beta-glucanase activity|endo-beta-1,3-1,4-glucanase activity|endo-1,3-1,4-beta-D-glucanase activity|beta-1,3-1,4-glucanase activity|laminaranase activity|1,3-(1,3;1,4)-beta-D-glucan 3(4)-glucanohydrolase activity				This term was made obsolete because it was representing two different activities, for which new GO terms have now been created: GO:0052861 glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group and GO:0052862 glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group.	GO:0052862|GO:0052861				True		MetaCyc:3.2.1.6-RXN|EC:3.2.1.6		molecular_function											owl:Class	
GO:2000050	biolink:NamedThing	regulation of non-canonical Wnt signaling pathway	Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway.	got7fsn_ti	regulation of non-canonical Wnt receptor signaling pathway|regulation of beta-catenin-independent Wnt receptor signaling pathway|regulation of non-canonical Wnt receptor signalling pathway|regulation of non-canonical Wnt-activated signaling pathway						jl	2010-08-20T01:04:12Z						biological_process											owl:Class	
GO:1904374	biolink:NamedThing	cellular response to kainic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.	got7fsn_ti							sl	2015-06-18T22:42:58Z						biological_process											owl:Class	
GO:0001134	biolink:NamedThing	obsolete transcription regulator recruiting activity	OBSOLETE. The function of binding to an RNA polymerase (RNAP) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.	got7fsn_ti	transcription factor recruiting transcription factor activity|transcription factor recruiting activity|transcription factor activity, transcription factor recruiting	https://github.com/geneontology/go-ontology/issues/18561|https://github.com/geneontology/go-ontology/issues/15577		GO:0003712	The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'.		krc	2011-01-20T04:57:59Z		True				molecular_function											owl:Class	
GO:0046586	biolink:NamedThing	regulation of calcium-dependent cell-cell adhesion	Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0009459	biolink:NamedThing	obsolete cytochrome a	OBSOLETE. A cytochrome containing heme a.	got7fsn_ti	cytochrome a			GO:0004129	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1900935	biolink:NamedThing	regulation of nonadec-1-ene biosynthetic process	Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process.	got7fsn_ti	regulation of nonadec-1-ene biosynthesis|regulation of nonadec-1-ene synthesis|regulation of nonadec-1-ene formation|regulation of nonadec-1-ene anabolism						tt	2012-06-14T03:13:34Z						biological_process											owl:Class	
GO:1901481	biolink:NamedThing	L-glutamate import involved in cellular response to nitrogen starvation	Any L-glutamate import that is involved in cellular response to nitrogen starvation.	got7fsn_ti	L-glutamate uptake involved in cellular response to nitrogen starvation						al	2012-10-08T08:32:29Z						biological_process											owl:Class	
GO:2000474	biolink:NamedThing	regulation of opioid receptor signaling pathway	Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway.	got7fsn_ti	regulation of opioid receptor signalling pathway						bf	2011-03-09T09:40:19Z						biological_process											owl:Class	
GO:0098709	biolink:NamedThing	glutathione import across plasma membrane	The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	glutathione uptake|glutathione import into cell						bf	2012-09-18T14:29:19Z			GO:0036347			biological_process											owl:Class	
GO:1903829	biolink:NamedThing	positive regulation of cellular protein localization	Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.	got7fsn_ti	up regulation of cellular protein localization|activation of cellular protein localization|positive regulation of channel localizer activity|up-regulation of cellular protein localization|up regulation of cellular protein localisation|activation of channel localizer activity|positive regulation of cellular protein localisation|upregulation of channel localizer activity|upregulation of cellular protein localisation|upregulation of cellular protein localization|up regulation of channel localizer activity|activation of cellular protein localisation|up-regulation of channel localizer activity|up-regulation of cellular protein localisation						jl	2015-01-20T14:32:33Z						biological_process											owl:Class	
GO:0002156	biolink:NamedThing	negative regulation of thyroid hormone mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway.	got7fsn_ti	negative regulation of thyroid hormone mediated signalling pathway						hjd	2009-11-19T12:41:48Z						biological_process											owl:Class	
GO:1902525	biolink:NamedThing	regulation of protein monoubiquitination	Any process that modulates the frequency, rate or extent of protein monoubiquitination.	got7fsn_ti	regulation of protein monoubiquitinylation|regulation of protein monoubiquitylation						ppm	2013-12-02T09:58:56Z						biological_process											owl:Class	
GO:0042761	biolink:NamedThing	very long-chain fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22.	got7fsn_ti	very-long-chain fatty acid formation|very-long-chain fatty acid biosynthetic process|very-long-chain fatty acid synthesis|very-long-chain fatty acid anabolism|very-long-chain fatty acid biosynthesis											MetaCyc:PWY-5080		biological_process											owl:Class	
GO:0048692	biolink:NamedThing	negative regulation of axon extension involved in regeneration	Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration.	got7fsn_ti	down-regulation of axon extension involved in regeneration|downregulation of axon extension involved in regeneration|down regulation of axon extension involved in regeneration|inhibition of axon extension involved in regeneration													biological_process											owl:Class	
GO:1901715	biolink:NamedThing	regulation of gamma-aminobutyric acid catabolic process	Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process.	got7fsn_ti	regulation of gamma-aminobutyric acid catabolism|regulation of 4-aminobutyrate catabolic process|regulation of GABA catabolic process|regulation of 4-aminobutanoate catabolism|regulation of gamma-aminobutyric acid degradation|regulation of GABA catabolism|regulation of 4-aminobutanoate catabolic process|regulation of gamma-aminobutyric acid breakdown|regulation of 4-aminobutyrate catabolism						mcc	2012-12-19T16:13:24Z						biological_process											owl:Class	
CHEBI:28995	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051370	biolink:NamedThing	obsolete ZASP binding	OBSOLETE. Binding to Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain.	got7fsn_ti	ZASP binding|Z-band alternatively spliced PDZ-motif protein binding			GO:0008092	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:0009144	biolink:NamedThing	purine nucleoside triphosphate metabolic process	The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine nucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0002610	biolink:NamedThing	regulation of plasmacytoid dendritic cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:1903639	biolink:NamedThing	regulation of gastrin-induced gastric acid secretion	Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion.	got7fsn_ti							sl	2014-11-20T20:54:20Z						biological_process											owl:Class	
GO:1900861	biolink:NamedThing	regulation of cordyol C biosynthetic process	Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process.	got7fsn_ti							di	2012-06-07T01:56:16Z						biological_process											owl:Class	
GO:2001138	biolink:NamedThing	regulation of phospholipid transport	Any process that modulates the frequency, rate or extent of phospholipid transport.	got7fsn_ti							kmv	2011-10-14T06:16:06Z						biological_process											owl:Class	
GO:0044339	biolink:NamedThing	canonical Wnt signaling pathway involved in osteoblast differentiation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in osteoblast differentiation|canonical Wnt receptor signaling pathway involved in osteoblast differentiation|canonical Wnt-activated signaling pathway involved in osteoblast differentiation						jl	2010-08-20T03:52:11Z						biological_process											owl:Class	
GO:0033533	biolink:NamedThing	verbascose metabolic process	The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	verbascose metabolism													biological_process											owl:Class	
GO:0075302	biolink:NamedThing	regulation of basidiospore formation	Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes.	got7fsn_ti														biological_process											owl:Class	
GO:0140360	biolink:NamedThing	cyclic-GMP-AMP transmembrane transporter activity	Enables the transfer of cyclic-GMP-AMP from one side of a membrane to the other.	got7fsn_ti							pg	2019-07-02T14:49:32Z						molecular_function											owl:Class	
GO:0072409	biolink:NamedThing	obsolete detection of stimulus involved in meiotic cell cycle checkpoint	OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a meiotic cell cycle checkpoint.	got7fsn_ti	meiotic cell cycle checkpoint sensor mechanism|meiotic cell cycle checkpoint sensor process|sensing involved in meiotic cell cycle checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:47:50Z		True				biological_process											owl:Class	
GO:1901572	biolink:NamedThing	obsolete chemical substance metabolic process	OBSOLETE. The chemical reactions and pathways involving chemical substance.	got7fsn_ti	chemical substance metabolism|chemical substance metabolic process				This term was obsoleted at the TermGenie Gatekeeper stage.		pr	2012-11-04T18:10:32Z		True				biological_process											owl:Class	
GO:0009023	biolink:NamedThing	obsolete tRNA sulfurtransferase	OBSOLETE. Catalysis of the reaction: L-cysteine + activated-tRNA = L-serine + tRNA containing a thionucleotide.	got7fsn_ti	tRNA sulphurtransferase activity|tRNA sulfurtransferase			GO:0034227		GO:0016783				True				molecular_function											owl:Class	
GO:0140550	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of phosphatidylinositol-4,5-bisphosphate.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20361					pg	2020-11-12T13:01:17Z						molecular_function											owl:Class	
GO:1900365	biolink:NamedThing	positive regulation of mRNA polyadenylation	Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.	got7fsn_ti	up regulation of cleavage and polyadenylylation specificity factor activity|upregulation of mRNA polyadenylation|up-regulation of mRNA polyadenylylation|activation of mRNA polyadenylylation|upregulation of cleavage and polyadenylylation specificity factor activity|up-regulation of mRNA polyadenylation|upregulation of mRNA polyadenylylation|activation of cleavage and polyadenylylation specificity factor activity|up regulation of mRNA polyadenylylation|up-regulation of cleavage and polyadenylylation specificity factor activity|activation of mRNA polyadenylation|positive regulation of mRNA polyadenylylation|up regulation of mRNA polyadenylation|positive regulation of cleavage and polyadenylylation specificity factor activity						pr	2012-04-12T04:36:39Z						biological_process											owl:Class	
GO:0090028	biolink:NamedThing	positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.	got7fsn_ti							tb	2009-08-03T10:25:27Z						biological_process											owl:Class	
GO:0005997	biolink:NamedThing	xylulose metabolic process	The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.	got7fsn_ti	xylulose metabolism													biological_process											owl:Class	
GO:0033466	biolink:NamedThing	trans-zeatin biosynthetic process	The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	got7fsn_ti	trans-zeatin formation|trans-zeatin biosynthesis|trans-zeatin anabolism|trans-zeatin synthesis											MetaCyc:PWY-2681		biological_process											owl:Class	
GO:1904593	biolink:NamedThing	prostaglandin binding	Binding to prostaglandin.	got7fsn_ti							sl	2015-08-21T18:53:31Z						molecular_function											owl:Class	
GO:0075084	biolink:NamedThing	obsolete modulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by host of symbiont transmembrane receptor-mediated cAMP signaling				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0044215	biolink:NamedThing	obsolete other organism	OBSOLETE. A secondary organism with which the first organism is interacting.	got7fsn_ti					This term was obsoleted because it represents an organism, which is outside the scope of GO.		jl	2009-11-12T01:04:58Z		True				cellular_component											owl:Class	
GO:0044693	biolink:NamedThing	trehalose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in).	got7fsn_ti	trehalose:hydrogen symporter activity						jl	2012-08-15T15:19:27Z						molecular_function											owl:Class	
GO:0140629	biolink:NamedThing	small conductance calcium-activated potassium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a small conductance calcium-activated potassium channel.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21175					pg	2021-03-25T09:53:57Z						molecular_function											owl:Class	
GO:0016136	biolink:NamedThing	saponin catabolic process	The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.	got7fsn_ti	saponin breakdown|saponin catabolism|saponin degradation													biological_process											owl:Class	
GO:0016354	biolink:NamedThing	obsolete cyclodiene susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cyclodiene susceptibility/resistance			GO:0046682	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0033020	biolink:NamedThing	cyclopentanol metabolic process	The chemical reactions and pathways involving cyclopentanol.	got7fsn_ti	cyclopentanol metabolism													biological_process											owl:Class	
GO:1900837	biolink:NamedThing	regulation of fumigaclavine C biosynthetic process	Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process.	got7fsn_ti	regulation of fumigaclavine C formation|regulation of fumigaclavine C biosynthesis|regulation of fumigaclavine C anabolism|regulation of fumigaclavine C synthesis						di	2012-06-07T09:36:22Z						biological_process											owl:Class	
GO:0017165	biolink:NamedThing	obsolete dipeptidase E activity	OBSOLETE. Catalysis of the hydrolysis of dipeptides Asp-Xaa; does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides.	got7fsn_ti	PepE gene product (Salmonella typhimurium) activity|peptidase E activity|dipeptidase E activity|aspartyl dipeptidase activity|alpha-aspartyl dipeptidase activity			GO:0016805	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0051793	biolink:NamedThing	medium-chain fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of any fatty acid with a chain length of between C6 and C12.	got7fsn_ti	medium-chain fatty acid breakdown|medium-chain fatty acid catabolism|medium chain fatty acid catabolic process|medium-chain fatty acid degradation|medium chain fatty acid catabolism													biological_process											owl:Class	
GO:0032910	biolink:NamedThing	regulation of transforming growth factor beta3 production	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.	got7fsn_ti	regulation of TGFB3 production|regulation of TGF-B3 production|regulation of transforming growth factor-beta3 production													biological_process											owl:Class	
GO:0034137	biolink:NamedThing	positive regulation of toll-like receptor 2 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.	got7fsn_ti	positive regulation of TLR2 signaling pathway|positive regulation of toll-like receptor 2 signalling pathway													biological_process											owl:Class	
GO:0046139	biolink:NamedThing	obsolete coenzyme and prosthetic group catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes and prosthetic groups.	got7fsn_ti	coenzyme and prosthetic group breakdown|coenzyme and prosthetic group catabolism|coenzyme and prosthetic group degradation|coenzyme and prosthetic group catabolic process				This term was made obsolete because it was replaced by more specific terms.	GO:0051190				True				biological_process											owl:Class	
GO:1900707	biolink:NamedThing	regulation of tensidol A biosynthetic process	Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process.	got7fsn_ti	regulation of tensidol A anabolism|regulation of tensidol A formation|regulation of tensidol A synthesis|regulation of tensidol A biosynthesis						di	2012-05-22T05:01:44Z						biological_process											owl:Class	
GO:0006762	biolink:NamedThing	obsolete dihydrofolate reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dihydrofolate reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0004146|GO:0046452				True				biological_process											owl:Class	
GO:1900452	biolink:NamedThing	regulation of long-term synaptic depression	Any process that modulates the frequency, rate or extent of long term synaptic depression.	got7fsn_ti	regulation of LTD|regulation of long term depression|regulation of long term synaptic depression						rl	2012-04-27T03:54:58Z						biological_process											owl:Class	
GO:0070827	biolink:NamedThing	obsolete chromatin maintenance	OBSOLETE. The chromatin organization process that preserves chromatin in a stable functional or structural state.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22013			This term was obsoleted because it is redundant with chromatin organization and assembly terms.		mah	2009-07-23T04:09:59Z		True				biological_process											owl:Class	
GO:0035607	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.	got7fsn_ti	FGF receptor signaling pathway involved in orbitofrontal cortex development|fibroblast growth factor receptor signalling pathway involved in orbitofrontal cortex development|FGFR signaling pathway involved in orbitofrontal cortex development						bf	2010-11-16T11:30:19Z						biological_process											owl:Class	
CL:1000272	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030212	biolink:NamedThing	hyaluronan metabolic process	The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.	got7fsn_ti	hyaluronan metabolism													biological_process											owl:Class	
GO:0051492	biolink:NamedThing	regulation of stress fiber assembly	Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.	got7fsn_ti	regulation of stress fibre formation|regulation of stress fibre biosynthesis													biological_process											owl:Class	
CHEBI:24271	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051608	biolink:NamedThing	histamine transport	The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	got7fsn_ti														biological_process											owl:Class	
GO:0032957	biolink:NamedThing	inositol trisphosphate metabolic process	The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.	got7fsn_ti	inositol trisphosphate metabolism|myo-inositol trisphosphate metabolic process|IP3 metabolism|IP3 metabolic process													biological_process											owl:Class	
CHEBI:21397	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901764	biolink:NamedThing	phosphinothricin metabolic process	The chemical reactions and pathways involving phosphinothricin.	got7fsn_ti	phosphinothricin metabolism						yaf	2013-01-15T10:02:37Z						biological_process											owl:Class	
GO:1903343	biolink:NamedThing	positive regulation of meiotic DNA double-strand break formation	Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation.	got7fsn_ti	up regulation of meiotic DNA double-strand break formation|activation of meiotic DNA double-strand break formation|up-regulation of meiotic DNA double-strand break formation|upregulation of meiotic DNA double-strand break formation						mcc	2014-08-18T21:32:11Z						biological_process											owl:Class	
GO:1901989	biolink:NamedThing	positive regulation of cell cycle phase transition	Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.	got7fsn_ti	activation of cell cycle transition|positive regulation of cell cycle transition|upregulation of cell cycle phase transition|up regulation of cell cycle transition|up regulation of cell cycle phase transition|upregulation of cell cycle transition|up-regulation of cell cycle phase transition|activation of cell cycle phase transition|up-regulation of cell cycle transition						jl	2013-03-19T16:11:37Z						biological_process											owl:Class	
GO:0097624	biolink:NamedThing	UDP-galactose transmembrane import into Golgi lumen	The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane.	got7fsn_ti	UDP-galactose import into Golgi lumen						pr	2014-08-18T14:59:23Z						biological_process											owl:Class	
GO:1904610	biolink:NamedThing	response to 3,3',4,4',5-pentachlorobiphenyl	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.	got7fsn_ti	response to PCB 126						sl	2015-08-27T18:52:49Z						biological_process											owl:Class	
GO:0075177	biolink:NamedThing	obsolete regulation of calcium or calmodulin-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|modulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
UBERON:0000483	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903950	biolink:NamedThing	negative regulation of AV node cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential.	got7fsn_ti	inhibition of AV node cell action potential|down-regulation of AV node cardiac muscle cell action potential|down-regulation of AV node cell action potential|negative regulation of AV node cardiac muscle cell action potential|downregulation of AV node cell action potential|negative regulation of atrioventricular node cardiac muscle cell action potential|downregulation of AV node cardiac muscle cell action potential|down regulation of AV node cardiac muscle cell action potential|inhibition of AV node cardiac muscle cell action potential|down-regulation of atrioventricular node cardiac muscle cell action potential|downregulation of atrioventricular node cardiac muscle cell action potential|down regulation of AV node cell action potential|inhibition of atrioventricular node cardiac muscle cell action potential|down regulation of atrioventricular node cardiac muscle cell action potential						nc	2015-02-20T14:59:41Z						biological_process											owl:Class	
GO:0090089	biolink:NamedThing	regulation of dipeptide transport	Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2009-10-23T11:24:36Z						biological_process											owl:Class	
GO:0015335	biolink:NamedThing	obsolete heavy metal ion:hydrogen symporter activity	OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in), where Me2+ is Fe2+, Zn2+, Mn2+, Cu2+, Cd2+, Co2+, Ni2+ or Pb2+.	got7fsn_ti	heavy metal ion:proton symporter activity|heavy metal ion:hydrogen symporter activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0046873|GO:0015295				True				molecular_function											owl:Class	
GO:0005909	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900546	biolink:NamedThing	obsolete positive regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of phenotypic switching.	got7fsn_ti	positive regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up-regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|activation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|upregulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|up regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up-regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|upregulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|activation of phenotypic switching by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		di	2012-05-14T11:36:05Z		True				biological_process											owl:Class	
GO:2000394	biolink:NamedThing	positive regulation of lamellipodium morphogenesis	Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis.	got7fsn_ti	positive regulation of lamellipodium organization						mah	2011-02-22T11:19:45Z						biological_process											owl:Class	
GO:0018930	biolink:NamedThing	3-methylquinoline metabolic process	The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.	got7fsn_ti	3-methylquinoline metabolism											UM-BBD_pathwayID:mqn		biological_process											owl:Class	
GO:0072712	biolink:NamedThing	response to thiabendazole	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.	got7fsn_ti	response to TBZ						mah	2012-04-11T04:23:56Z						biological_process											owl:Class	
GO:0009493	biolink:NamedThing	obsolete adrenodoxin-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	adrenodoxin-type ferredoxin			GO:0009055	This term was made obsolete because it does not represent a function.					True				molecular_function											owl:Class	
GO:0046520	biolink:NamedThing	sphingoid biosynthetic process	The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.	got7fsn_ti	sphingoid anabolism|sphingoid biosynthesis|sphingoid formation|sphingoid synthesis													biological_process											owl:Class	
GO:0030636	biolink:NamedThing	obsolete acetate derivative biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of derivatives of acetic acid.	got7fsn_ti	acetate derivative synthesis|acetate derivative anabolism|acetate derivative biosynthesis|acetate derivative formation|acetate derivative biosynthetic process				This term was made obsolete because it is an unnecessary grouping term and has been replaced by terms to describe metabolism of specific compounds.	GO:1900620				True				biological_process											owl:Class	
GO:0006172	biolink:NamedThing	ADP biosynthetic process	The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.	got7fsn_ti	ADP synthesis|ADP formation|ADP biosynthesis|ADP anabolism													biological_process											owl:Class	
GO:0035730	biolink:NamedThing	S-nitrosoglutathione binding	Binding to S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.	got7fsn_ti	GSNO binding						bf	2011-03-11T09:57:19Z						molecular_function											owl:Class	
GO:0008992	biolink:NamedThing	obsolete repressor LexA activity	OBSOLETE. Catalysis of the hydrolysis of Ala-Gly bond in repressor lexA.	got7fsn_ti	repressor LexA activity|LexA repressor|repressor lexA			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0098504	biolink:NamedThing	obsolete DNA 3' dephosphorylation involved in DNA repair	OBSOLETE. Any 3' DNA dephosphorylation that is involved in the process of DNA repair.	got7fsn_ti					This term was obsoleted because it represents a molecular function, and not a specific coordinated process.		dos	2013-09-18T14:52:15Z		True				biological_process											owl:Class	
GO:1903875	biolink:NamedThing	corticosterone binding	Binding to corticosterone.	got7fsn_ti							mr	2015-02-06T16:02:35Z						molecular_function											owl:Class	
GO:0090300	biolink:NamedThing	positive regulation of neural crest formation	Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.	got7fsn_ti							tb	2010-03-12T04:08:26Z						biological_process											owl:Class	
GO:1903120	biolink:NamedThing	protein localization to actin filament bundle	A process in which a protein is transported to, or maintained in, the location of an actin filament bundle.	got7fsn_ti	protein localisation in actin filament bundle|protein localization in actin filament bundle|protein localization to actin cable|protein localisation to actin filament bundle						mah	2014-06-16T11:27:16Z						biological_process											owl:Class	
GO:0001627	biolink:NamedThing	obsolete leucine-rich G-protein receptor-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	leucine-rich G-protein receptor-like receptor activity|leucine-rich G protein receptor-like receptor activity|LGR-like receptor				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True				molecular_function											owl:Class	
GO:2000025	biolink:NamedThing	regulation of leaf formation	Any process that modulates the frequency, rate or extent of leaf formation.	got7fsn_ti							tb	2010-08-05T11:25:37Z						biological_process											owl:Class	
GO:0044460	biolink:NamedThing	obsolete flagellum part	OBSOLETE. Any constituent part of a flagellum, a long whiplike or feathery structure borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium.	got7fsn_ti	flagellum part|flagellum component				This term was made obsolete because it was an unnecessary grouping term. Eukaryotic flagella were deemed to be equivalent to cilia and merged, so the only remaining child to this term was 'bacterial-type flagellum part ; GO:0044461'.					True				cellular_component											owl:Class	
GO:2000405	biolink:NamedThing	negative regulation of T cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.	got7fsn_ti	negative regulation of T-lymphocyte migration|negative regulation of T-cell migration|negative regulation of T lymphocyte migration						mah	2011-02-23T10:48:52Z						biological_process											owl:Class	
GO:0018881	biolink:NamedThing	bromoxynil metabolic process	The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants.	got7fsn_ti	bromoxynil metabolism											UM-BBD_pathwayID:box		biological_process											owl:Class	
GO:0009479	biolink:NamedThing	obsolete cytochrome f	OBSOLETE. A cytochrome c that is characteristic of green plants and transfers electrons to plastocyanin.	got7fsn_ti	cytochrome f			GO:0045158	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0010271	biolink:NamedThing	regulation of chlorophyll catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll.	got7fsn_ti														biological_process											owl:Class	
GO:0062172	biolink:NamedThing	lutein catabolic process	The chemical reactions and pathways resulting in the breakdown of lutein.	got7fsn_ti	lutein catabolism|lutein breakdown|lutein degradation						dph	2019-11-18T16:06:07Z						biological_process											owl:Class	
OIO:hasScope	biolink:NamedThing	has_scope		got7fsn_ti																									owl:AnnotationProperty	
GO:0010593	biolink:NamedThing	negative regulation of lamellipodium assembly	Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.	got7fsn_ti	negative regulation of lamellipodium biogenesis													biological_process											owl:Class	
GO:0150118	biolink:NamedThing	negative regulation of cell-substrate junction organization	Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization.	got7fsn_ti							bc	2019-11-14T12:16:32Z						biological_process											owl:Class	
GO:2000971	biolink:NamedThing	negative regulation of detection of glucose	Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose.	got7fsn_ti	negative regulation of glucose perception|negative regulation of glucose sensing|negative regulation of glucose detection						vk	2011-08-02T10:18:54Z						biological_process											owl:Class	
GO:0016248	biolink:NamedThing	channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a channel.	got7fsn_ti														molecular_function											owl:Class	
GO:1905337	biolink:NamedThing	positive regulation of aggrephagy	Any process that activates or increases the frequency, rate or extent of aggrephagy.	got7fsn_ti	up regulation of aggrephagy|upregulation of aggrephagy|up-regulation of aggrephagy|activation of aggrephagy						pad	2016-07-26T13:42:02Z						biological_process											owl:Class	
CHEBI:35251	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903534	biolink:NamedThing	regulation of lactose biosynthetic process	Any process that modulates the frequency, rate or extent of lactose biosynthetic process.	got7fsn_ti	regulation of lactose anabolism|regulation of lactose synthesis|regulation of lactose biosynthesis|regulation of lactose formation						mr	2014-10-08T16:26:05Z						biological_process											owl:Class	
GO:0046852	biolink:NamedThing	positive regulation of bone remodeling	Any process that activates or increases the frequency, rate or extent of bone remodeling.	got7fsn_ti	up regulation of bone remodeling|upregulation of bone remodeling|activation of bone remodeling|stimulation of bone remodeling|up-regulation of bone remodeling													biological_process											owl:Class	
GO:0035423	biolink:NamedThing	obsolete inactivation of MAPK activity involved in innate immune response	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.		bf	2010-03-29T01:28:59Z		True				biological_process											owl:Class	
GO:2000797	biolink:NamedThing	regulation of amniotic stem cell differentiation	Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation.	got7fsn_ti							yaf	2011-06-29T02:18:59Z						biological_process											owl:Class	
GO:1902871	biolink:NamedThing	positive regulation of amacrine cell differentiation	Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.	got7fsn_ti	up regulation of amacrine cell differentiation|up regulation of amacrine neuron differentiation|up-regulation of amacrine neuron differentiation|positive regulation of amacrine neuron differentiation|activation of amacrine neuron differentiation|upregulation of amacrine cell differentiation|activation of amacrine cell differentiation|up-regulation of amacrine cell differentiation|upregulation of amacrine neuron differentiation						mr	2014-04-03T15:24:46Z						biological_process											owl:Class	
GO:0046669	biolink:NamedThing	regulation of compound eye retinal cell programmed cell death	Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.	got7fsn_ti	regulation of retinal cell programmed cell death													biological_process											owl:Class	
GO:1902165	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.	got7fsn_ti	regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis						lb	2013-05-22T12:45:10Z						biological_process											owl:Class	
GO:0075081	biolink:NamedThing	obsolete modulation by host of symbiont transmembrane receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0106022	biolink:NamedThing	positive regulation of vesicle docking	Any process that activates or increases the frequency, rate or extent of vesicle docking.	got7fsn_ti	positive regulation of vesicle to membrane docking						hjd	2017-05-16T14:12:32Z						biological_process											owl:Class	
GO:0010625	biolink:NamedThing	positive regulation of Schwann cell proliferation	Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.	got7fsn_ti														biological_process											owl:Class	
GO:1990923	biolink:NamedThing	PET complex	A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs.	got7fsn_ti							sp	2016-01-14T02:19:39Z						cellular_component											owl:Class	
GO:2001104	biolink:NamedThing	heptasaccharide transport	The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:29:58Z						biological_process											owl:Class	
GO:0031452	biolink:NamedThing	negative regulation of heterochromatin assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.	got7fsn_ti	down regulation of heterochromatin formation|inhibition of heterochromatin formation|negative regulation of heterochromatin formation|down-regulation of heterochromatin formation|downregulation of heterochromatin formation													biological_process											owl:Class	
GO:0046384	biolink:NamedThing	2-deoxyribose 1-phosphate metabolic process	The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.	got7fsn_ti	deoxyribose 1-phosphate metabolic process|2-deoxyribose 1-phosphate metabolism|deoxyribose 1-phosphate metabolism										GO:0046388			biological_process											owl:Class	
GO:0030830	biolink:NamedThing	obsolete negative regulation of cGMP catabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.	got7fsn_ti	down-regulation of cGMP catabolic process|downregulation of cGMP catabolic process|down regulation of cGMP catabolic process|negative regulation of cGMP catabolism|negative regulation of cGMP degradation|inhibition of cGMP catabolic process|negative regulation of cGMP breakdown				The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism.					True				biological_process											owl:Class	
GO:0003817	biolink:NamedThing	obsolete complement factor D activity	OBSOLETE. Catalysis of the cleavage of component factor B (Arg-Lys) when in complex with C3b or with cobra venom factor (CVF).	got7fsn_ti	C3 proactivator convertase activity|factor D|C3 convertase activator activity|adipsin|factor D (complement)|properdin factor D esterase activity|complement factor D activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0032227	biolink:NamedThing	negative regulation of synaptic transmission, dopaminergic	Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.	got7fsn_ti	inhibition of synaptic transmission, dopaminergic|down-regulation of synaptic transmission, dopaminergic|downregulation of synaptic transmission, dopaminergic|down regulation of synaptic transmission, dopaminergic													biological_process											owl:Class	
GO:0045594	biolink:NamedThing	positive regulation of cumulus cell differentiation	Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation.	got7fsn_ti	activation of cumulus cell differentiation|up regulation of cumulus cell differentiation|stimulation of cumulus cell differentiation|positive regulation of ovarian cumulus cell differentiation|upregulation of cumulus cell differentiation|up-regulation of cumulus cell differentiation													biological_process											owl:Class	
GO:0019324	biolink:NamedThing	L-lyxose metabolic process	The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.	got7fsn_ti	L-lyxose metabolism											MetaCyc:LYXMET-PWY		biological_process											owl:Class	
GO:0045571	biolink:NamedThing	negative regulation of imaginal disc growth	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.	got7fsn_ti	down-regulation of imaginal disc growth|inhibition of imaginal disc growth|down regulation of imaginal disc growth|downregulation of imaginal disc growth													biological_process											owl:Class	
GO:2000155	biolink:NamedThing	positive regulation of cilium-dependent cell motility	Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.	got7fsn_ti	positive regulation of ciliary cell motility						mah	2010-10-04T12:41:05Z						biological_process											owl:Class	
GO:0033348	biolink:NamedThing	tetrose biosynthetic process	The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.	got7fsn_ti	tetrose biosynthesis|tetrose formation|tetrose synthesis|tetrose anabolism													biological_process											owl:Class	
GO:0150176	biolink:NamedThing	positive regulation of phosphatidylethanolamine metabolic process	Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process.	got7fsn_ti							bc	2020-01-21T14:04:32Z						biological_process											owl:Class	
GO:1902977	biolink:NamedThing	mitotic DNA replication preinitiation complex assembly	Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle.	got7fsn_ti	pre-IC complex assembly involved in mitotic cell cycle|DNA replication preinitiation complex formation involved in mitotic cell cycle						jl	2014-05-06T19:19:37Z						biological_process											owl:Class	
GO:0002187	biolink:NamedThing	mitochondrial creatine kinase complex	An octomeric protein complex having creatine kinase activity.	got7fsn_ti							hjd	2011-06-14T02:15:29Z						cellular_component											owl:Class	
GO:0140430	biolink:NamedThing	positive regulation of chromosome passenger complex localization to kinetochore	Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore.	got7fsn_ti							pg	2020-02-19T05:19:45Z						biological_process											owl:Class	
GO:0052777	biolink:NamedThing	diacetylchitobiose catabolic process	The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products.	got7fsn_ti	diacetylchitobiose catabolism													biological_process											owl:Class	
GO:0052420	biolink:NamedThing	obsolete metabolism by host of symbiont xylan	OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because there is no evidence it exists.					True				biological_process											owl:Class	
CHEBI:24870	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071638	biolink:NamedThing	negative regulation of monocyte chemotactic protein-1 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.	got7fsn_ti	negative regulation of MCP-1 production|negative regulation of CCL2 production						mah	2010-02-12T10:39:51Z						biological_process											owl:Class	
GO:1904127	biolink:NamedThing	regulation of convergent extension involved in somitogenesis	Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis.	got7fsn_ti							dph	2015-04-10T21:13:04Z						biological_process											owl:Class	
GO:0044132	biolink:NamedThing	obsolete development of symbiont on or near host	OBSOLETE. The progression of a symbiont from an initial condition to a later condition, within the cells or tissues of its host organism.	got7fsn_ti					The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-04T03:36:02Z		True				biological_process											owl:Class	
GO:2000776	biolink:NamedThing	histone H4 acetylation involved in response to DNA damage stimulus	Any histone H4 acetylation that is involved in a response to DNA damage stimulus.	got7fsn_ti	histone H4 acetylation of cellular DNA damage response|histone H4 acetylation of response to genotoxic stress|histone H4 acetylation of cellular response to DNA damage stimulus|histone H4 acetylation of response to DNA damage stimulus|histone H4 acetylation of DNA damage response						mah	2011-06-22T04:00:54Z						biological_process											owl:Class	
GO:0052147	biolink:NamedThing	obsolete positive energy taxis in host	OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive energy taxis within host	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0030171	biolink:NamedThing	voltage-gated proton channel activity	Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	voltage-dependent proton channel activity|voltage gated proton channel activity													molecular_function											owl:Class	
GO:1901049	biolink:NamedThing	atropine metabolic process	The chemical reactions and pathways involving atropine.	got7fsn_ti	atropine metabolism						yaf	2012-06-28T04:51:25Z						biological_process											owl:Class	
GO:1904312	biolink:NamedThing	cellular response to gold(3+)	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.	got7fsn_ti							sl	2015-06-10T17:41:13Z						biological_process											owl:Class	
GO:1901788	biolink:NamedThing	benzoyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA.	got7fsn_ti	benzoyl-CoA catabolism|benzoyl-CoA degradation|benzoyl-CoA breakdown						yaf	2013-01-16T11:13:59Z						biological_process											owl:Class	
GO:0150177	biolink:NamedThing	negative regulation of phosphatidylethanolamine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process.	got7fsn_ti							bc	2020-01-21T14:05:00Z						biological_process											owl:Class	
GO:0071309	biolink:NamedThing	cellular response to phylloquinone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.	got7fsn_ti	cellular response to vitamin K1						mah	2009-12-10T04:37:18Z						biological_process											owl:Class	
GO:1900526	biolink:NamedThing	obsolete negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of phosphatidylserine synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine anabolism by negative regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-03T05:14:10Z		True				biological_process											owl:Class	
GO:0048228	biolink:NamedThing	obsolete actin cortical patch distribution	OBSOLETE. Any process that establishes the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells.	got7fsn_ti	actin cortical patch distribution				This term was made obsolete because its definition is very similar to that of its parent term, actin cortical patch localization (GO:0051666), but somewhat unclear, and not similar enough to merge the terms.					True				biological_process											owl:Class	
GO:0062013	biolink:NamedThing	positive regulation of small molecule metabolic process	Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.	got7fsn_ti	positive regulation of small molecule metabolism						dph	2018-03-19T14:25:10Z						biological_process											owl:Class	
GO:2001007	biolink:NamedThing	negative regulation of cellulose biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.	got7fsn_ti	negative regulation of cellulose synthesis|negative regulation of cellulose anabolism|negative regulation of cellulose biosynthesis|negative regulation of cellulose formation						tt	2011-08-08T08:42:24Z						biological_process											owl:Class	
GO:1902610	biolink:NamedThing	response to N-phenylthiourea	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.	got7fsn_ti							rjd	2014-01-08T01:57:49Z						biological_process											owl:Class	
GO:1901536	biolink:NamedThing	negative regulation of DNA demethylation	Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation.	got7fsn_ti	inhibition of DNA demethylation|down-regulation of DNA demethylation|downregulation of DNA demethylation|down regulation of DNA demethylation						jl	2012-10-24T13:52:54Z						biological_process											owl:Class	
GO:1905755	biolink:NamedThing	protein localization to cytoplasmic microtubule	A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule.	got7fsn_ti	protein localisation to cytoplasmic microtubule						mah	2016-12-12T15:31:07Z						biological_process											owl:Class	
GO:1900477	biolink:NamedThing	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter	Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti							dgf	2012-05-01T09:01:04Z						biological_process											owl:Class	
GO:0032781	biolink:NamedThing	positive regulation of ATPase activity	Any process that activates or increases the rate of ATP hydrolysis by an ATPase.	got7fsn_ti	up-regulation of ATPase activity|stimulation of ATPase activity|up regulation of ATPase activity|positive regulation of adenosinetriphosphatase activity|activation of ATPase activity|upregulation of ATPase activity													biological_process											owl:Class	
GO:0090007	biolink:NamedThing	obsolete regulation of mitotic anaphase	OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic anaphase, a cell cycle process comprising the steps by which a cell progresses through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other.	got7fsn_ti	regulation of mitotic anaphase				This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		tb	2009-07-17T01:08:58Z		True				biological_process											owl:Class	
GO:0060863	biolink:NamedThing	regulation of floral organ abscission by signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.	got7fsn_ti							dph	2009-08-12T04:07:41Z						biological_process											owl:Class	
GO:0033506	biolink:NamedThing	glucosinolate biosynthetic process from homomethionine	The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine.	got7fsn_ti	glucosinolate formation from homomethionine|glucosinolate synthesis from homomethionine|glucosinolate biosynthesis from homomethionine|glucosinolate anabolism from homomethionine											MetaCyc:PWY-1187		biological_process											owl:Class	
GO:0032378	biolink:NamedThing	negative regulation of intracellular lipid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.	got7fsn_ti	inhibition of intracellular lipid transport|down-regulation of intracellular lipid transport|downregulation of intracellular lipid transport|down regulation of intracellular lipid transport													biological_process											owl:Class	
GO:0046654	biolink:NamedThing	tetrahydrofolate biosynthetic process	The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.	got7fsn_ti	tetrahydrofolate biosynthesis|tetrahydrofolate formation|tetrahydrofolate synthesis|tetrahydrofolate anabolism											MetaCyc:FOLSYN-PWY		biological_process											owl:Class	
GO:1901446	biolink:NamedThing	negative regulation of response to propan-1-ol	Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol.	got7fsn_ti	down regulation of response to propan-1-ol|inhibition of response to propan-1-ol|downregulation of response to propan-1-ol|down-regulation of response to propan-1-ol						tt	2012-10-02T14:13:52Z						biological_process											owl:Class	
CHEBI:30849	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32689	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070291	biolink:NamedThing	N-acylethanolamine metabolic process	The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group.	got7fsn_ti	N-acylethanolamine metabolism|NAE metabolism|NAE metabolic process													biological_process											owl:Class	
GO:1904344	biolink:NamedThing	regulation of gastric mucosal blood circulation	Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation.	got7fsn_ti	regulation of stomach mucosal blood circulation						sl	2015-06-11T21:20:31Z						biological_process											owl:Class	
GO:0046198	biolink:NamedThing	obsolete cresol biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.	got7fsn_ti	cresol anabolism|cresol synthesis|cresol biosynthetic process|cresol biosynthesis|cresol formation			GO:0042212	This term was made obsolete because cresol is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:1903597	biolink:NamedThing	negative regulation of gap junction assembly	Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly.	got7fsn_ti	down-regulation of gap junction assembly|downregulation of gap junction assembly|inhibition of gap junction assembly|down regulation of gap junction assembly						rl	2014-11-07T18:51:45Z						biological_process											owl:Class	
GO:0002589	biolink:NamedThing	regulation of antigen processing and presentation of peptide antigen via MHC class I	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.	got7fsn_ti	regulation of peptide antigen processing and presentation via MHC class I													biological_process											owl:Class	
GO:0120060	biolink:NamedThing	regulation of gastric emptying	Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.	got7fsn_ti	regulation of small bowel emptying|regulation of small intestine emptying						krc	2017-06-13T21:47:16Z						biological_process											owl:Class	
GO:0072159	biolink:NamedThing	epithelial cell migration involved in proximal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis.	got7fsn_ti							mah	2010-02-24T02:37:08Z						biological_process											owl:Class	
GO:0043568	biolink:NamedThing	positive regulation of insulin-like growth factor receptor signaling pathway	Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling.	got7fsn_ti	up-regulation of insulin-like growth factor receptor signaling pathway|up regulation of insulin-like growth factor receptor signaling pathway|stimulation of insulin-like growth factor receptor signaling pathway|activation of insulin-like growth factor receptor signaling pathway|positive regulation of IGF receptor signalling pathway|upregulation of insulin-like growth factor receptor signaling pathway|positive regulation of insulin-like growth factor receptor signalling pathway|positive regulation of IGF receptor signaling pathway													biological_process											owl:Class	
GO:0052374	biolink:NamedThing	obsolete negative regulation by symbiont of entry into host	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	downregulation by symbiont of entry into host|down regulation by symbiont of entry into host|inhibition by symbiont of entry into host|down-regulation by symbiont of entry into host	https://github.com/geneontology/go-ontology/issues/18779			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0042996	biolink:NamedThing	regulation of Golgi to plasma membrane protein transport	Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
CHEBI:59295	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052134	biolink:NamedThing	obsolete negative aerotaxis on or near host	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0007256	biolink:NamedThing	obsolete activation of JNKK activity	OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.	got7fsn_ti	positive regulation of JUNKK activity|activation of JUN kinase kinase activity	https://github.com/geneontology/go-ontology/issues/21307			This term was obsoleted because it represents a molecular function.	GO:0046328|GO:0043539				True				biological_process											owl:Class	
GO:2000586	biolink:NamedThing	regulation of platelet-derived growth factor receptor-beta signaling pathway	Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.	got7fsn_ti	regulation of betaPDGF receptor signaling pathway|regulation of platelet-derived growth factor receptor-beta signalling pathway|regulation of PDGFR-beta signaling pathway|regulation of PDGF receptor-beta signaling pathway						bf	2011-04-07T03:27:48Z						biological_process											owl:Class	
GO:0004226	biolink:NamedThing	obsolete Gly-X carboxypeptidase activity	OBSOLETE. Catalysis of the reaction: peptidyl-Gly-Xaa + H2O = peptidyl-Gly + Xaa.	got7fsn_ti	carboxypeptidase S activity|glycine carboxypeptidase activity|carboxypeptidase a|peptidase alpha|Gly-Xaa carboxypeptidase activity|yeast carboxypeptidase activity|Gly-X carboxypeptidase activity			GO:0004181	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0008224	biolink:NamedThing	obsolete Gram-positive antibacterial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, Gram-positive bacterial cells.	got7fsn_ti	Gram-positive antibacterial peptide activity				This term was made obsolete because it describes involvement in a process and not a function.	GO:0050830				True				molecular_function											owl:Class	
GO:0035360	biolink:NamedThing	positive regulation of peroxisome proliferator activated receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	got7fsn_ti	positive regulation of peroxisome proliferator activated receptor signalling pathway|positive regulation of peroxisome proliferator-activated receptor signaling pathway|positive regulation of PPAR signaling pathway						bf	2010-03-05T10:43:10Z						biological_process											owl:Class	
GO:0140472	biolink:NamedThing	cell cortex of non-growing cell tip	The region directly beneath the plasma membrane at the cell tip at which no growth takes place.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17249					pg	2020-06-18T13:33:58Z						cellular_component											owl:Class	
GO:1902659	biolink:NamedThing	regulation of glucose mediated signaling pathway	Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway.	got7fsn_ti	regulation of glucose mediated signalling						di	2014-01-28T17:54:21Z						biological_process											owl:Class	
GO:1901083	biolink:NamedThing	pyrrolizidine alkaloid metabolic process	The chemical reactions and pathways involving pyrrolizidine alkaloid.	got7fsn_ti	pyrrolizidine alkaloid metabolism						yaf	2012-07-05T10:27:56Z						biological_process											owl:Class	
GO:0006797	biolink:NamedThing	polyphosphate metabolic process	The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid.	got7fsn_ti	polyphosphate metabolism													biological_process											owl:Class	
GO:1904881	biolink:NamedThing	cellular response to hydrogen sulfide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.	got7fsn_ti	cellular response to dihydridosulfur|cellular response to sulfane						sl	2016-01-04T23:56:35Z						biological_process											owl:Class	
GO:2000519	biolink:NamedThing	positive regulation of T-helper 1 cell activation	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation.	got7fsn_ti	positive regulation of Th1 cell activation						ebc	2011-03-22T10:40:31Z						biological_process											owl:Class	
GO:0033310	biolink:NamedThing	chlorophyll a catabolic process	The chemical reactions and pathways leading to the breakdown of chlorophyll a.	got7fsn_ti	chlorophyll a breakdown|chlorophyll a catabolism|chlorophyll a degradation											MetaCyc:PWY-5098|MetaCyc:PWY-5086		biological_process											owl:Class	
CHEBI:18421	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006324	biolink:NamedThing	obsolete S phase-specific histone modification	OBSOLETE. The covalent alteration of one or more amino acid residues within a histone protein that takes place during, and results in a modification pattern characteristic of, S phase of the cell cycle.	got7fsn_ti	S phase-specific histone modification|S-phase-specific histone modification				This term was made obsolete because histone modification already exists and the phase specificity is better captured as an annotation extension.	GO:0016570				True				biological_process											owl:Class	
GO:1900256	biolink:NamedThing	regulation of beta1-adrenergic receptor activity	Any process that modulates the frequency, rate or extent of beta1-adrenergic receptor activity.	got7fsn_ti	regulation of beta1 adrenoceptor						tb	2012-04-03T10:59:21Z						biological_process											owl:Class	
GO:1900076	biolink:NamedThing	regulation of cellular response to insulin stimulus	Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus.	got7fsn_ti							yaf	2012-01-31T11:22:22Z						biological_process											owl:Class	
CHEBI:71063	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098527	biolink:NamedThing	neuromuscular junction of somatic muscle	A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods.	got7fsn_ti							dos	2013-10-14T12:07:05Z						cellular_component											owl:Class	
GO:1903700	biolink:NamedThing	caecum development	The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure.	got7fsn_ti	blind intestine development|blindgut development|intestinum crassum cecum development|cecum development|caeca development|intestinum crassum caecum development|intestinum caecum development|ceca development						cls	2014-12-03T12:05:00Z						biological_process											owl:Class	
GO:0046588	biolink:NamedThing	negative regulation of calcium-dependent cell-cell adhesion	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion.	got7fsn_ti	down-regulation of calcium-dependent cell-cell adhesion|down regulation of calcium-dependent cell-cell adhesion|downregulation of calcium-dependent cell-cell adhesion|inhibition of calcium-dependent cell-cell adhesion													biological_process											owl:Class	
CHEBI:60252	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010869	biolink:NamedThing	obsolete regulation of receptor biosynthetic process	OBSOLETE. Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1901280	biolink:NamedThing	D-ribose 5-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate.	got7fsn_ti	D-ribose 5-phosphate synthesis|D-ribose 5-phosphate anabolism|D-ribose 5-phosphate formation|D-ribose 5-phosphate biosynthesis						yaf	2012-08-17T15:00:27Z						biological_process											owl:Class	
GO:0015601	biolink:NamedThing	obsolete cystine/diaminopimelate porter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).	got7fsn_ti	cystine/diaminopimelate porter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015626|GO:0015426|GO:0015184				True				molecular_function											owl:Class	
GO:2000790	biolink:NamedThing	regulation of mesenchymal cell proliferation involved in lung development	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.	got7fsn_ti							pr	2011-06-24T01:53:50Z						biological_process											owl:Class	
GO:1901641	biolink:NamedThing	ITP binding	Binding to ITP.	got7fsn_ti							tb	2012-11-15T22:56:39Z						molecular_function											owl:Class	
GO:1900347	biolink:NamedThing	positive regulation of methane biosynthetic process from methanethiol	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol.	got7fsn_ti	upregulation of methane biosynthetic process from methanethiol|up regulation of methane biosynthetic process from methanethiol|activation of methane biosynthetic process from methanethiol|up-regulation of methane biosynthetic process from methanethiol						tt	2012-04-06T02:10:06Z						biological_process											owl:Class	
GO:1904412	biolink:NamedThing	regulation of cardiac ventricle development	Any process that modulates the frequency, rate or extent of cardiac ventricle development.	got7fsn_ti							sl	2015-06-25T19:52:15Z						biological_process											owl:Class	
GO:1900866	biolink:NamedThing	glycolate transport	The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							pr	2012-06-12T04:29:56Z						biological_process											owl:Class	
GO:2000654	biolink:NamedThing	regulation of cellular response to testosterone stimulus	Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.	got7fsn_ti							vk	2011-05-02T03:23:56Z						biological_process											owl:Class	
GO:1905611	biolink:NamedThing	negative regulation of mRNA cap binding	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding.	got7fsn_ti	downregulation of mRNA cap binding|down regulation of mRNA cap binding|inhibition of mRNA cap binding|down-regulation of mRNA cap binding						bc	2016-10-28T11:27:36Z						biological_process											owl:Class	
GO:0032925	biolink:NamedThing	regulation of activin receptor signaling pathway	Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.	got7fsn_ti	regulation of activin signalling pathway|regulation of activin signaling pathway|regulation of activin receptor signalling pathway													biological_process											owl:Class	
CHEBI:26873	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000819	biolink:NamedThing	regulation of nucleotide-excision repair	Any process that modulates the frequency, rate or extent of nucleotide-excision repair.	got7fsn_ti	regulation of intrastrand cross-link repair|regulation of interstrand crosslink repair|regulation of NER|regulation of pyrimidine-dimer repair, DNA damage excision						pr	2011-07-13T08:55:39Z						biological_process											owl:Class	
GO:0006055	biolink:NamedThing	CMP-N-acetylneuraminate biosynthetic process	The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.	got7fsn_ti	CMP-N-acetylneuraminate synthesis|CMP-N-acetylneuraminate formation|CMP-N-acetylneuraminate biosynthesis|CMP-N-acetylneuraminate anabolism													biological_process											owl:Class	
GO:2000688	biolink:NamedThing	obsolete positive regulation of rubidium ion transmembrane transporter activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity.	got7fsn_ti	positive regulation of Rb+ transmembrane transporter activity|positive regulation of rubidium transmembrane transporter activity|positive regulation of rubidium cation transmembrane transporter activity				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-11T09:27:33Z		True				biological_process											owl:Class	
GO:0002707	biolink:NamedThing	negative regulation of lymphocyte mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.	got7fsn_ti	down-regulation of lymphocyte mediated immunity|inhibition of lymphocyte mediated immunity|downregulation of lymphocyte mediated immunity|down regulation of lymphocyte mediated immunity													biological_process											owl:Class	
GO:0008576	biolink:NamedThing	obsolete vesicle-fusing ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by an AAA-ATPase, involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments.	got7fsn_ti	vesicle-fusing ATPase activity			GO:0016887	This term was made obsolete because it incorporates process information.	GO:0061025|GO:0016192				True				molecular_function											owl:Class	
GO:0070785	biolink:NamedThing	negative regulation of growth of unicellular organism as a thread of attached cells	Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.	got7fsn_ti							mah	2009-07-07T02:37:21Z						biological_process											owl:Class	
GO:0033144	biolink:NamedThing	negative regulation of intracellular steroid hormone receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.	got7fsn_ti	negative regulation of steroid hormone receptor signalling pathway|negative regulation of steroid hormone receptor signaling pathway													biological_process											owl:Class	
GO:0031272	biolink:NamedThing	regulation of pseudopodium assembly	Any process that modulates the frequency, rate or extent of the assembly of pseudopodia.	got7fsn_ti	regulation of pseudopodium formation													biological_process											owl:Class	
GO:0035707	biolink:NamedThing	T-helper 2 cell chemotaxis	The directed movement of a T-helper 2 cell in response to an external stimulus.	got7fsn_ti	Th2 cell chemotaxis						bf	2011-03-02T02:37:44Z						biological_process											owl:Class	
GO:2000888	biolink:NamedThing	arabinoxylan-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of an arabinoxylan.	got7fsn_ti	arabinoxylan catabolic process|arabinoxylan catabolism						jl	2011-07-28T09:31:50Z						biological_process											owl:Class	
GO:0061334	biolink:NamedThing	cell rearrangement involved in Malpighian tubule morphogenesis	The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.	got7fsn_ti	cell migration involved in Malpighian tubule morphogenesis						dph	2010-09-28T02:04:05Z						biological_process											owl:Class	
GO:0009804	biolink:NamedThing	coumarin metabolic process	The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.	got7fsn_ti	coumarin metabolism													biological_process											owl:Class	
GO:1905115	biolink:NamedThing	regulation of lateral attachment of mitotic spindle microtubules to kinetochore	Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.	got7fsn_ti							al	2016-04-07T14:25:25Z						biological_process											owl:Class	
GO:0000101	biolink:NamedThing	sulfur amino acid transport	The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	sulphur amino acid transport													biological_process											owl:Class	
GO:0019895	biolink:NamedThing	obsolete kinesin-associated mitochondrial adaptor activity	OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17668			This term was obsoleted because it represents the function of a specific protein.					True				molecular_function											owl:Class	
GO:0008164	biolink:NamedThing	obsolete organophosphorus resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	organophosphorus resistance			GO:0046683	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0070833	biolink:NamedThing	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine	The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.	got7fsn_ti							mah	2009-07-29T03:51:39Z				MetaCyc:PWY4FS-3		biological_process											owl:Class	
GO:0017092	biolink:NamedThing	obsolete sterol regulatory element-binding protein site 2 protease activity	OBSOLETE. Catalysis of the cleavage, within the membrane-spanning helix, of the amino-terminal half (the intermediate form) of sterol regulatory element binding protein (SREBP). This activity releases the transcription factor domain of SREBP from the membrane, freeing it to enter the nucleus.	got7fsn_ti	SREBP site 2 protease activity|sterol regulatory element-binding protein site 2 protease activity			GO:0008237	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1900329	biolink:NamedThing	positive regulation of mannotriose transport	Any process that activates or increases the frequency, rate or extent of mannotriose transport.	got7fsn_ti	activation of mannotriose transport|upregulation of mannotriose transport|up-regulation of mannotriose transport|up regulation of mannotriose transport						tt	2012-04-06T01:50:22Z						biological_process											owl:Class	
GO:0060587	biolink:NamedThing	regulation of lipoprotein lipid oxidation	Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.	got7fsn_ti							dph	2009-05-08T02:27:02Z						biological_process											owl:Class	
GO:0044333	biolink:NamedThing	Wnt signaling pathway involved in digestive tract morphogenesis	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the generation and the organization of the digestive tract.	got7fsn_ti	Wnt receptor signalling pathway involved in digestive tract morphogenesis|Wnt receptor signaling pathway involved in digestive tract morphogenesis|Wnt-activated signaling pathway involved in digestive tract morphogenesis						jl	2010-08-20T11:36:23Z						biological_process											owl:Class	
GO:0061862	biolink:NamedThing	cellular response to differentiation-inducing factor 2	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.	got7fsn_ti	cellular response to DIF-2|cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one|cellular response to DIF2						dph	2017-04-07T17:14:16Z						biological_process											owl:Class	
GO:0090266	biolink:NamedThing	regulation of mitotic cell cycle spindle assembly checkpoint	Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.	got7fsn_ti							tb	2010-02-05T02:06:37Z						biological_process											owl:Class	
GO:1905421	biolink:NamedThing	regulation of plant organ morphogenesis	Any process that modulates the frequency, rate or extent of plant organ morphogenesis.	got7fsn_ti							tb	2016-09-06T23:00:14Z						biological_process											owl:Class	
GO:0072351	biolink:NamedThing	tricarboxylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.	got7fsn_ti	tricarboxylate biosynthesis|tricarboxylate biosynthetic process|tricarboxylic acid anabolism|tricarboxylic acid biosynthesis|tricarboxylic acid formation|tricarboxylic acid synthesis						mah	2010-11-11T05:08:54Z						biological_process											owl:Class	
GO:0046241	biolink:NamedThing	obsolete m-xylene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	m-xylene biosynthetic process|m-xylene anabolism|m-xylene biosynthesis|meta-xylene biosynthetic process|meta-xylene biosynthesis|m-xylene formation|m-xylene synthesis			GO:0018949	This term was made obsolete because m-xylene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0019349	biolink:NamedThing	ribitol metabolic process	The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin.	got7fsn_ti	ribitol metabolism													biological_process											owl:Class	
CL:0000014	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035984	biolink:NamedThing	cellular response to trichostatin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.	got7fsn_ti							bf	2011-08-23T01:48:43Z						biological_process											owl:Class	
GO:0015641	biolink:NamedThing	obsolete lipoprotein toxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lipoprotein toxin				This term was made obsolete because it represents a gene product.	GO:0090729				True				molecular_function											owl:Class	
GO:2000324	biolink:NamedThing	positive regulation of glucocorticoid receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway.	got7fsn_ti	positive regulation of glucocorticoid receptor signalling pathway						vk	2011-01-18T04:39:05Z						biological_process											owl:Class	
GO:1900689	biolink:NamedThing	regulation of gliotoxin biosynthetic process	Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process.	got7fsn_ti	regulation of gliotoxin formation|regulation of gliotoxin anabolism|regulation of gliotoxin synthesis|regulation of gliotoxin biosynthesis						di	2012-05-22T04:51:38Z						biological_process											owl:Class	
GO:1901983	biolink:NamedThing	regulation of protein acetylation	Any process that modulates the frequency, rate or extent of protein acetylation.	got7fsn_ti	regulation of protein amino acid acetylation						ss	2013-03-14T00:40:07Z						biological_process											owl:Class	
GO:1902848	biolink:NamedThing	negative regulation of neuronal signal transduction	Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction.	got7fsn_ti	down-regulation of neuronal signal transduction|down regulation of neuronal signal transduction|downregulation of neuronal signal transduction|inhibition of neuronal signal transduction						sjp	2014-04-02T10:11:18Z						biological_process											owl:Class	
GO:0071503	biolink:NamedThing	response to heparin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.	got7fsn_ti							mah	2009-12-18T03:33:49Z						biological_process											owl:Class	
UBERON:0009850	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902886	biolink:NamedThing	obsolete negative regulation of proteasome-activating ATPase activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity.	got7fsn_ti	down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|inhibition of proteasomal ATPase activity|down-regulation of proteasomal ATPase activity|downregulation of proteasome channel opening activity|down regulation of proteasome channel gating activity|downregulation of proteasome channel gating activity|inhibition of proteasome channel gating activity|downregulation of proteasome-activating ATPase activity|downregulation of proteasomal ATPase activity|inhibition of proteasome channel opening activity|down regulation of proteasomal ATPase activity|down-regulation of proteasome-activating ATPase activity|downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process|negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|down regulation of proteasome channel opening activity|negative regulation of proteasome channel gating activity|negative regulation of proteasomal ATPase activity|inhibition of proteasome-activating ATPase activity|down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|down regulation of proteasome-activating ATPase activity|negative regulation of proteasome channel opening activity|inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process|down-regulation of proteasome channel opening activity|down-regulation of proteasome channel gating activity	https://github.com/geneontology/go-ontology/issues/20879			This term was obsoleted because it represents a molecular function.		di	2014-04-04T17:35:30Z		True				biological_process											owl:Class	
GO:0038090	biolink:NamedThing	positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.	got7fsn_ti	positive regulation of cell migration by VEGF/PDGFR signaling pathway|positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signalling pathway|VEGF/PDGFR-induced cell migration						bf	2012-02-02T03:41:23Z						biological_process											owl:Class	
GO:0085025	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by Tat complex	OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by symbiont of host morphology or physiology via protein secreted by the Tat secretion system				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:47:01Z		True				biological_process											owl:Class	
GO:1901006	biolink:NamedThing	ubiquinone-6 biosynthetic process	The chemical reactions and pathways resulting in the formation of ubiquinone-6.	got7fsn_ti	ubiquinone-6 anabolism|ubiquinone-6 synthesis|ubiquinone-6 biosynthesis|ubiquinone-6 formation						bf	2012-06-15T09:59:58Z						biological_process											owl:Class	
GO:1903391	biolink:NamedThing	regulation of adherens junction organization	Any process that modulates the frequency, rate or extent of adherens junction organization.	got7fsn_ti	regulation of adherens junction organisation|regulation of adherens junction assembly and maintenance						als	2014-08-27T10:08:38Z						biological_process											owl:Class	
GO:1903680	biolink:NamedThing	acinar cell of sebaceous gland differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland.	got7fsn_ti	sebocyte differentiation						cls	2014-11-30T11:51:57Z						biological_process											owl:Class	
GO:0023019	biolink:NamedThing	signal transduction involved in regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.	got7fsn_ti	regulation of gene expression as a consequence of signal transmission							2010-02-16T09:30:50Z						biological_process											owl:Class	
GO:0090453	biolink:NamedThing	aspartate transmembrane import into vacuole	The directed movement of aspartate into the vacuole across the vacuolar membrane.	got7fsn_ti	vacuolar aspartate import						tb	2012-09-24T14:12:46Z						biological_process											owl:Class	
GO:0080021	biolink:NamedThing	response to benzoic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.	got7fsn_ti	response to benzoic acid stimulus													biological_process											owl:Class	
GO:0060149	biolink:NamedThing	negative regulation of posttranscriptional gene silencing	Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.	got7fsn_ti														biological_process											owl:Class	
GO:2000613	biolink:NamedThing	negative regulation of thyroid-stimulating hormone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion.	got7fsn_ti	negative regulation of TSH secretion|negative regulation of thyroid stimulating hormone secretion						yaf	2011-04-18T12:56:20Z						biological_process											owl:Class	
GO:0008487	biolink:NamedThing	obsolete prenyl-dependent CAAX protease activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	prenyl-dependent CAAX protease activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:2000963	biolink:NamedThing	regulation of cellooligosaccharide catabolic process	Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process.	got7fsn_ti	regulation of cellooligosaccharide catabolism						tt	2011-08-01T02:28:36Z						biological_process											owl:Class	
GO:0043370	biolink:NamedThing	regulation of CD4-positive, alpha-beta T cell differentiation	Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.	got7fsn_ti	regulation of CD4-positive, alpha beta T cell development|regulation of CD4-positive, alpha beta T-cell differentiation|regulation of CD4-positive, alpha beta T lymphocyte differentiation|regulation of CD4-positive T lymphocyte differentiation|regulation of CD4-positive, alpha beta T-lymphocyte differentiation|regulation of CD4-positive T-lymphocyte differentiation|regulation of CD4-positive T-cell differentiation|regulation of CD4-positive, alpha beta T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0018984	biolink:NamedThing	naphthalenesulfonate metabolic process	The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene.	got7fsn_ti	naphthalenesulphonate metabolic process|naphthalenesulfonate metabolism|naphthalenesulphonate metabolism										GO:0018932	UM-BBD_pathwayID:nphs		biological_process											owl:Class	
GO:0071659	biolink:NamedThing	negative regulation of IP-10 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10.	got7fsn_ti	negative regulation of chemokine (C-C motif) ligand 10 production|negative regulation of CXCL10 production						mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:0023050	biolink:NamedThing	obsolete consequence of signal transmission	OBSOLETE. The steps whereby the downstream processes started by a signal are brought to a conclusion. Examples include destruction of cAMP by PDE, or endocytosis resulting from receptor phosphorylation. The termination process ends when the receptor has returned to its inactive state.	got7fsn_ti	consequence of signal transmission|signal termination				This term was made obsolete because the term is no longer needed.			2010-02-16T09:30:50Z		True				biological_process											owl:Class	
CHEBI:65117	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990616	biolink:NamedThing	magnesium ion export from mitochondrion	The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore.	got7fsn_ti	magnesium ion efflux from mitochondrion						mcc	2015-01-21T22:06:42Z						biological_process											owl:Class	
GO:0001028	biolink:NamedThing	obsolete RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	got7fsn_ti	RNA polymerase III type 2 promoter polymerase recruiting transcription factor activity				The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter.		krc	2010-08-23T12:52:01Z		True				molecular_function											owl:Class	
GO:0035336	biolink:NamedThing	long-chain fatty-acyl-CoA metabolic process	The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.	got7fsn_ti	long-chain fatty acyl CoA metabolic process|long-chain fatty acyl-CoA metabolism						bf	2010-03-02T11:01:43Z						biological_process											owl:Class	
GO:0150078	biolink:NamedThing	positive regulation of neuroinflammatory response	Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.	got7fsn_ti							bc	2018-07-26T12:35:50Z						biological_process											owl:Class	
GO:1903442	biolink:NamedThing	response to lipoic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.	got7fsn_ti							jl	2014-09-17T13:52:03Z						biological_process											owl:Class	
GO:0075171	biolink:NamedThing	obsolete regulation of MAP kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont MAP kinase-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:2000691	biolink:NamedThing	negative regulation of cardiac muscle cell myoblast differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.	got7fsn_ti	negative regulation of cardiac myoblast differentiation|negative regulation of myocardial precursor cell differentiation						yaf	2011-05-25T09:08:06Z						biological_process											owl:Class	
GO:0006157	biolink:NamedThing	deoxyadenosine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.	got7fsn_ti	deoxyadenosine degradation|deoxyadenosine catabolism|deoxyadenosine phosphorolysis|deoxyadenosine breakdown										GO:0006159			biological_process											owl:Class	
CHEBI:49552	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001628	biolink:NamedThing	obsolete gastropyloric receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	gastropyloric receptor activity|GPR receptor				This term was made obsolete because the gastropyloric receptor is a type of neuron.					True				molecular_function											owl:Class	
GO:0035396	biolink:NamedThing	positive regulation of chemokine (C-X-C motif) ligand 9 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.	got7fsn_ti	positive regulation of MIG production|positive regulation of CXCL9 production						bf	2010-03-23T10:07:17Z						biological_process											owl:Class	
GO:1904658	biolink:NamedThing	positive regulation of sensory perception of sweet taste	Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste.	got7fsn_ti	activation of sensory perception of sweet taste|up regulation of sweet taste perception|up-regulation of sweet taste perception|up regulation of sensory perception of sweet taste|upregulation of sweet taste perception|upregulation of sensory perception of sweet taste|up-regulation of sensory perception of sweet taste|activation of sweet taste perception|positive regulation of sweet taste perception						mr	2015-09-04T16:43:24Z						biological_process											owl:Class	
GO:0001076	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase II transcription factor binding	OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	RNA polymerase II transcription factor binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0061629|GO:0140110	krc	2010-10-22T02:49:32Z		True				molecular_function											owl:Class	
GO:0018922	biolink:NamedThing	iprodione metabolic process	The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium).	got7fsn_ti	iprodione metabolism											UM-BBD_pathwayID:ipd		biological_process											owl:Class	
GO:2000977	biolink:NamedThing	regulation of forebrain neuron differentiation	Any process that modulates the frequency, rate or extent of forebrain neuron differentiation.	got7fsn_ti							yaf	2011-08-03T12:09:12Z						biological_process											owl:Class	
GO:1905636	biolink:NamedThing	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.	got7fsn_ti	up regulation of RNA polymerase II regulatory region sequence-specific DNA binding|activation of RNA polymerase II regulatory region sequence-specific DNA binding|up-regulation of RNA polymerase II regulatory region sequence-specific DNA binding|upregulation of RNA polymerase II regulatory region sequence-specific DNA binding						bc	2016-11-03T12:03:07Z						biological_process											owl:Class	
GO:0085012	biolink:NamedThing	obsolete interaction with host via protein secreted by Tat complex	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Tat complex. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with host via protein secreted by Tat secretion system				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:29:37Z		True				biological_process											owl:Class	
CHEBI:23643	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098799	biolink:NamedThing	outer mitochondrial membrane protein complex	Any protein complex that is part of the outer mitochondrial membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0019804	biolink:NamedThing	obsolete quinolinate synthetase complex	OBSOLETE. A heterodimer which acts as a quinolinate synthetase; quinolinate synthetase B (L-aspartate oxidase) catalyzes the oxidation of L-aspartate to L-iminoaspartate; quinolinate synthetase A condenses L-imidoaspartate and dihydroxyacetone to quinolinate.	got7fsn_ti	quinolinate synthetase complex				This term was made obsolete because there is no evidence that a physical complex forms; although the phrase "quinolinate synthetase complex" is occasionally used in the literature, it refers to two enzymes that act as monomers.	GO:0008743|GO:0008987				True				cellular_component											owl:Class	
GO:0090381	biolink:NamedThing	regulation of heart induction	Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.	got7fsn_ti							tb	2010-10-04T10:23:43Z						biological_process											owl:Class	
GO:0006002	biolink:NamedThing	fructose 6-phosphate metabolic process	The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.	got7fsn_ti	fructose 6-phosphate metabolism													biological_process											owl:Class	
GO:1900900	biolink:NamedThing	negative regulation of heptadecane metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process.	got7fsn_ti	inhibition of heptadecane metabolism|downregulation of heptadecane metabolic process|inhibition of heptadecane metabolic process|down regulation of heptadecane metabolism|down-regulation of heptadecane metabolic process|down-regulation of heptadecane metabolism|downregulation of heptadecane metabolism|negative regulation of heptadecane metabolism|down regulation of heptadecane metabolic process						tt	2012-06-13T03:30:25Z						biological_process											owl:Class	
GO:0015191	biolink:NamedThing	L-methionine transmembrane transporter activity	Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.	got7fsn_ti	L-methionine transporter activity													molecular_function											owl:Class	
GO:1905960	biolink:NamedThing	response to differentiation-inducing factor 2	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.	got7fsn_ti	response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one|response to DIF-2|response to DIF2						tb	2017-02-22T18:45:40Z						biological_process											owl:Class	
CHEBI:25214	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900460	biolink:NamedThing	obsolete negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of colony morphology by negative regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T06:09:17Z		True				biological_process											owl:Class	
GO:0062134	biolink:NamedThing	positive regulation of L-glutamine biosynthetic process	Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis.	got7fsn_ti							dph	2019-06-27T13:49:29Z						biological_process											owl:Class	
GO:1901196	biolink:NamedThing	positive regulation of calcium-mediated signaling involved in cellular response to salt stress	Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress.	got7fsn_ti	positive regulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signalling involved in cellular response to salt stress|up regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|stimulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up-regulation of calcium-mediated signaling involved in cellular salinity response|up regulation of calcium-mediated signaling involved in cellular salinity response|up regulation of calcium-mediated signaling involved in cellular response to salt stress|upregulation of calcium-mediated signaling involved in cellular response to salt stress|upregulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|positive regulation of calcium-mediated signalling involved in cellular salinity response|up-regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|upregulation of calcium-mediated signaling involved in cellular salinity response|up-regulation of calcium-mediated signaling involved in cellular response to salt stress|stimulation of calcium-mediated signaling involved in cellular response to salt stress|activation of calcium-mediated signaling involved in cellular salinity response|activation of calcium-mediated signaling involved in cellular response to salt stress|activation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|positive regulation of calcium-mediated signalling involved in cellular response to ionic osmotic stress|stimulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress						al	2012-07-27T10:52:56Z						biological_process											owl:Class	
GO:0060901	biolink:NamedThing	regulation of hair cycle by canonical Wnt signaling pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle.	got7fsn_ti	regulation of hair cycle by canonical Wnt receptor signaling pathway|regulation of hair cycle by canonical Wnt receptor signalling pathway|regulation of hair cycle by canonical Wnt-activated signaling pathway|regulation of hair cycle by Wnt receptor signaling pathway through beta-catenin						dph	2009-08-13T02:41:10Z						biological_process											owl:Class	
GO:0106060	biolink:NamedThing	regulation of exit from meiosis	Any process that modulates the frequency, rate or extent of exit from mitosis.	got7fsn_ti							hjd	2017-10-18T16:48:01Z						biological_process											owl:Class	
GO:1903282	biolink:NamedThing	regulation of glutathione peroxidase activity	Any process that modulates the frequency, rate or extent of glutathione peroxidase activity.	got7fsn_ti	regulation of selenium-glutathione peroxidase activity|regulation of glutathione:hydrogen-peroxide oxidoreductase activity|regulation of reduced glutathione peroxidase activity|regulation of GSH peroxidase activity|regulation of non-selenium glutathione peroxidase activity						bf	2014-08-11T13:14:13Z						biological_process											owl:Class	
GO:0070189	biolink:NamedThing	kynurenine metabolic process	The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.	got7fsn_ti	kynurenine metabolism													biological_process											owl:Class	
GO:0015394	biolink:NamedThing	uridine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in).	got7fsn_ti	nucleoside (uridine) permease activity|uridine:hydrogen ion symporter activity													molecular_function											owl:Class	
GO:0050669	biolink:NamedThing	negative regulation of homocysteine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.	got7fsn_ti	negative regulation of Hcy metabolism|down-regulation of homocysteine metabolic process|negative regulation of Hcy metabolic process|downregulation of homocysteine metabolic process|down regulation of homocysteine metabolic process|inhibition of homocysteine metabolic process|negative regulation of homocysteine metabolism													biological_process											owl:Class	
GO:1900337	biolink:NamedThing	negative regulation of methane biosynthetic process from carbon monoxide	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide.	got7fsn_ti	inhibition of methane biosynthetic process from carbon monoxide|down-regulation of methane biosynthetic process from carbon monoxide|down regulation of methane biosynthetic process from carbon monoxide|downregulation of methane biosynthetic process from carbon monoxide						tt	2012-04-06T02:03:24Z						biological_process											owl:Class	
GO:1905287	biolink:NamedThing	positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation	Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation.	got7fsn_ti	positive regulation of mitotic entry involved in cellular response to nitrogen starvation						al	2016-06-21T17:19:33Z						biological_process											owl:Class	
GO:0019459	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005094	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903153	biolink:NamedThing	obsolete ferrous iron transmembrane transporter activity involved in ferrous iron import into cell	OBSOLETE. Any ferrous iron transmembrane transporter activity that is involved in ferrous iron import into cell.	got7fsn_ti	ferrous iron transmembrane transporter activity involved in ferrous ion import into cell|ferrous iron transmembrane transporter activity involved in ferrous iron import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:53Z		True				molecular_function											owl:Class	
GO:0009229	biolink:NamedThing	thiamine diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.	got7fsn_ti	thiamine diphosphate formation|thiamine pyrophosphate biosynthetic process|thiamine pyrophosphate biosynthesis|thiamin diphosphate biosynthetic process|TPP biosynthesis|thiamine diphosphate anabolism|thiamin pyrophosphate biosynthetic process|thiamine diphosphate biosynthesis|thiamin pyrophosphate biosynthesis|TPP biosynthetic process|thiamine diphosphate synthesis													biological_process											owl:Class	
GO:0061023	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0039649	biolink:NamedThing	modulation by virus of host ubiquitin-protein ligase activity	The process in which a virus effects a change in host ubiquitin-protein ligase activity. Ubiquitin-protein ligase activity catalyzes the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.	got7fsn_ti	modulation of host E3 ubiquitin ligases by virus						bf	2012-10-09T15:26:56Z						biological_process											owl:Class	
GO:1900157	biolink:NamedThing	regulation of bone mineralization involved in bone maturation	Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation.	got7fsn_ti							vk	2012-03-07T08:55:07Z						biological_process											owl:Class	
GO:0001786	biolink:NamedThing	phosphatidylserine binding	Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.	got7fsn_ti														molecular_function											owl:Class	
GO:1902546	biolink:NamedThing	positive regulation of DNA N-glycosylase activity	Any process that activates or increases the frequency, rate or extent of DNA N-glycosylase activity.	got7fsn_ti	up regulation of DNA N-glycosylase activity|up-regulation of endonuclease VIII activity|up regulation of DNA glycosylase activity|upregulation of DNA glycosylase activity|positive regulation of endonuclease VIII activity|activation of endonuclease VIII activity|activation of DNA glycosylase activity|up-regulation of DNA glycosylase activity|up regulation of endonuclease VIII activity|upregulation of DNA N-glycosylase activity|positive regulation of DNA glycosylase activity|up-regulation of DNA N-glycosylase activity|activation of DNA N-glycosylase activity|upregulation of endonuclease VIII activity						rph	2013-12-04T14:18:12Z						biological_process											owl:Class	
GO:0006551	biolink:NamedThing	leucine metabolic process	The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.	got7fsn_ti	leucine metabolism													biological_process											owl:Class	
GO:2000005	biolink:NamedThing	negative regulation of metanephric S-shaped body morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis.	got7fsn_ti							jl	2010-07-30T02:14:37Z						biological_process											owl:Class	
GO:0015900	biolink:NamedThing	benomyl transport	The directed movement of benomyl into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.	got7fsn_ti														biological_process											owl:Class	
GO:0070861	biolink:NamedThing	regulation of protein exit from endoplasmic reticulum	Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.	got7fsn_ti	regulation of protein exit from ER|regulation of protein export from ER|regulation of protein export from endoplasmic reticulum						mah	2009-08-17T03:39:18Z						biological_process											owl:Class	
GO:1903921	biolink:NamedThing	regulation of protein processing in phagocytic vesicle	Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle.	got7fsn_ti	regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|regulation of protein maturation by peptide bond hydrolysis in phagosome|regulation of protein maturation by proteolysis in phagosome|regulation of peptidolysis during protein maturation in phagocytic vesicle|regulation of protein processing in phagosome|regulation of protein maturation by proteolysis in phagocytic vesicle|regulation of peptidolysis during protein maturation in phagosome|regulation of protein maturation by peptide bond cleavage in phagosome|regulation of protein maturation by peptide bond cleavage in phagocytic vesicle						als	2015-02-10T11:16:54Z						biological_process											owl:Class	
PO:0009055	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900659	biolink:NamedThing	negative regulation of emericellamide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process.	got7fsn_ti	negative regulation of emericellamide biosynthesis|down-regulation of emericellamide anabolism|down regulation of emericellamide biosynthetic process|negative regulation of emericellamide anabolism|inhibition of emericellamide biosynthetic process|down regulation of emericellamide synthesis|down-regulation of emericellamide biosynthesis|down-regulation of emericellamide synthesis|inhibition of emericellamide formation|down-regulation of emericellamide formation|down regulation of emericellamide biosynthesis|downregulation of emericellamide synthesis|down regulation of emericellamide formation|down-regulation of emericellamide biosynthetic process|downregulation of emericellamide anabolism|negative regulation of emericellamide synthesis|inhibition of emericellamide anabolism|inhibition of emericellamide biosynthesis|inhibition of emericellamide synthesis|downregulation of emericellamide biosynthetic process|negative regulation of emericellamide formation|down regulation of emericellamide anabolism|downregulation of emericellamide biosynthesis|downregulation of emericellamide formation						di	2012-05-22T04:10:44Z						biological_process											owl:Class	
GO:0086095	biolink:NamedThing	positive regulation of IKACh channel activity by G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G protein-coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate.	got7fsn_ti	positive regulation of IKACh channel activity by G-protein coupled acetylcholine receptor signaling|Gbeta/gamma-coupled muscarinic receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signaling pathway involved in activation of IKACH|cardiac muscarinic receptor signaling via Gbeta/gamma|muscarinic receptor signaling pathway involved in ion channel activation						bf							biological_process											owl:Class	
GO:0005888	biolink:NamedThing	obsolete proteoglycan integral to plasma membrane	OBSOLETE. Penetrating at least one phospholipid bilayer of a plasma membrane and consisting of proteoglycan. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer.	got7fsn_ti	proteoglycan integral to plasma membrane			GO:0005887	This term was made obsolete because it describes the composition (i.e. proteoglycan) and not the location of a gene product.					True				cellular_component											owl:Class	
GO:1905812	biolink:NamedThing	regulation of motor neuron axon guidance	Any process that modulates the frequency, rate or extent of motor neuron axon guidance.	got7fsn_ti	regulation of motor axon guidance|regulation of motor axon pathfinding|regulation of motoneuron axon guidance						hbye	2017-01-12T13:25:12Z						biological_process											owl:Class	
GO:0043938	biolink:NamedThing	positive regulation of sporulation	Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:2001218	biolink:NamedThing	obsolete negative regulation of S/G2 transition of mitotic cell cycle	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of S/G2 transition of mitotic cell cycle.	got7fsn_ti	negative regulation of S/G2 transition of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.		dph	2011-11-16T09:14:47Z		True				biological_process											owl:Class	
GO:0019524	biolink:NamedThing	keto-D-gluconate catabolic process	The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.	got7fsn_ti	keto-D-gluconate degradation|keto-D-gluconate catabolism|keto-D-gluconate breakdown											MetaCyc:DHGLUCONATE-PYR-CAT-PWY		biological_process											owl:Class	
UBERON:0004666	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034181	biolink:NamedThing	positive regulation of toll-like receptor 13 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway.	got7fsn_ti	positive regulation of toll-like receptor 13 signalling pathway|positive regulation of TLR13 signaling pathway													biological_process											owl:Class	
GO:0061949	biolink:NamedThing	regulation of premature acrosome loss	Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.	got7fsn_ti							dph	2017-10-25T17:51:32Z						biological_process											owl:Class	
GO:0150140	biolink:NamedThing	regulation of CD86 production	Any process that modulates the frequency, rate or extent of CD86 biosynthetic process.	got7fsn_ti	regulation of CD86 biosynthetic process						bc	2019-12-08T09:31:00Z						biological_process											owl:Class	
GO:1900148	biolink:NamedThing	negative regulation of Schwann cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.	got7fsn_ti	downregulation of Schwann cell migration|down-regulation of Schwann cell migration|down regulation of Schwann cell migration|inhibition of Schwann cell migration						bf	2012-03-06T04:14:55Z						biological_process											owl:Class	
GO:0046119	biolink:NamedThing	7-methylguanosine catabolic process	The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.	got7fsn_ti	7-methylguanosine degradation|7-methylguanosine breakdown|7-methylguanosine catabolism													biological_process											owl:Class	
GO:0052011	biolink:NamedThing	obsolete catabolism by symbiont of host cell wall pectin	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of host cell wall pectin	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0090084	biolink:NamedThing	negative regulation of inclusion body assembly	Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	got7fsn_ti							tb	2009-10-23T11:08:56Z						biological_process											owl:Class	
GO:0080142	biolink:NamedThing	regulation of salicylic acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid.	got7fsn_ti							dhl	2009-05-19T04:38:23Z						biological_process											owl:Class	
GO:1900631	biolink:NamedThing	tridecane metabolic process	The chemical reactions and pathways involving tridecane.	got7fsn_ti	tridecane metabolism						tt	2012-05-21T06:41:16Z						biological_process											owl:Class	
GO:0006583	biolink:NamedThing	melanin biosynthetic process from tyrosine	The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.	got7fsn_ti	melanin formation from tyrosine|melanin synthesis from tyrosine|melanin anabolism from tyrosine													biological_process											owl:Class	
GO:1903646	biolink:NamedThing	positive regulation of chaperone-mediated protein folding	Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding.	got7fsn_ti	up regulation of chaperone-mediated protein folding|activation of chaperone-mediated protein folding|upregulation of chaperone-mediated protein folding|up-regulation of chaperone-mediated protein folding						pga	2014-11-21T15:25:44Z						biological_process											owl:Class	
GO:1905394	biolink:NamedThing	retromer complex binding	Binding to a retromer complex.	got7fsn_ti							bc	2016-08-24T14:00:32Z						molecular_function											owl:Class	
GO:0008436	biolink:NamedThing	obsolete heterogeneous nuclear ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	heterogeneous nuclear ribonucleoprotein|hnRNP			GO:1990904	This term was made obsolete because it describes a cellular component rather than a molecular function.					True				molecular_function											owl:Class	
GO:1902416	biolink:NamedThing	positive regulation of mRNA binding	Any process that activates or increases the frequency, rate or extent of mRNA binding.	got7fsn_ti	activation of mRNA binding|upregulation of mRNA binding|up regulation of mRNA binding|up-regulation of mRNA binding						rb	2013-09-13T18:57:24Z						biological_process											owl:Class	
GO:1905723	biolink:NamedThing	negative regulation of trypanothione biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process.	got7fsn_ti	downregulation of trypanothione formation|inhibition of trypanothione synthesis|negative regulation of trypanothione synthesis|down-regulation of trypanothione anabolism|down regulation of trypanothione anabolism|down regulation of trypanothione biosynthesis|down-regulation of trypanothione biosynthesis|down regulation of trypanothione synthesis|down regulation of trypanothione formation|downregulation of trypanothione anabolism|negative regulation of trypanothione biosynthesis|inhibition of trypanothione anabolism|down regulation of trypanothione biosynthetic process|inhibition of trypanothione biosynthesis|down-regulation of trypanothione synthesis|negative regulation of trypanothione anabolism|downregulation of trypanothione synthesis|downregulation of trypanothione biosynthetic process|inhibition of trypanothione formation|negative regulation of trypanothione formation|down-regulation of trypanothione biosynthetic process|down-regulation of trypanothione formation|downregulation of trypanothione biosynthesis|inhibition of trypanothione biosynthetic process						rz	2016-11-25T14:44:42Z						biological_process											owl:Class	
CHEBI:17057	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900958	biolink:NamedThing	positive regulation of 17-methylnonadec-1-ene biosynthetic process	Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.	got7fsn_ti	upregulation of 17-methylnonadec-1-ene formation|upregulation of 17-methylnonadec-1-ene biosynthetic process|positive regulation of 17-methylnonadec-1-ene anabolism|up regulation of 17-methylnonadec-1-ene anabolism|up regulation of 17-methylnonadec-1-ene synthesis|upregulation of 17-methylnonadec-1-ene biosynthesis|activation of 17-methylnonadec-1-ene anabolism|activation of 17-methylnonadec-1-ene formation|upregulation of 17-methylnonadec-1-ene anabolism|up regulation of 17-methylnonadec-1-ene formation|up-regulation of 17-methylnonadec-1-ene formation|up-regulation of 17-methylnonadec-1-ene synthesis|up-regulation of 17-methylnonadec-1-ene biosynthetic process|positive regulation of 17-methylnonadec-1-ene biosynthesis|up regulation of 17-methylnonadec-1-ene biosynthesis|activation of 17-methylnonadec-1-ene biosynthesis|activation of 17-methylnonadec-1-ene biosynthetic process|activation of 17-methylnonadec-1-ene synthesis|upregulation of 17-methylnonadec-1-ene synthesis|up-regulation of 17-methylnonadec-1-ene anabolism|up-regulation of 17-methylnonadec-1-ene biosynthesis|positive regulation of 17-methylnonadec-1-ene formation|up regulation of 17-methylnonadec-1-ene biosynthetic process|positive regulation of 17-methylnonadec-1-ene synthesis						tt	2012-06-14T03:27:46Z						biological_process											owl:Class	
GO:0045598	biolink:NamedThing	regulation of fat cell differentiation	Any process that modulates the frequency, rate or extent of adipocyte differentiation.	got7fsn_ti	regulation of adipocyte differentiation|regulation of adipocyte cell differentiation													biological_process											owl:Class	
GO:0052493	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016821	biolink:NamedThing	obsolete hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement			GO:0016817	This term was made obsolete because it incorporates process information.					True				molecular_function											owl:Class	
GO:0023044	biolink:NamedThing	obsolete signaling via chemical mediator	OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a chemical mediator.	got7fsn_ti	signalling via chemical mediator|signaling via chemical mediator				This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:1904973	biolink:NamedThing	positive regulation of viral translation	Any process that activates or increases the frequency, rate or extent of viral translation.	got7fsn_ti	activation of viral protein synthesis|activation of viral protein anabolism|upregulation of viral protein anabolism|upregulation of viral protein formation|up-regulation of viral protein formation|up regulation of viral protein formation|up regulation of viral protein anabolism|upregulation of viral protein biosynthesis|up regulation of viral protein synthesis|up regulation of viral protein biosynthetic process|positive regulation of viral protein synthesis|activation of viral translation|up-regulation of viral protein synthesis|upregulation of viral translation|positive regulation of viral protein anabolism|positive regulation of viral protein biosynthesis|positive regulation of viral protein formation|up-regulation of viral protein anabolism|up-regulation of viral protein biosynthetic process|positive regulation of viral protein biosynthetic process|activation of viral protein formation|up regulation of viral translation|up regulation of viral protein biosynthesis|up-regulation of viral translation|activation of viral protein biosynthetic process|upregulation of viral protein biosynthetic process|up-regulation of viral protein biosynthesis|activation of viral protein biosynthesis|upregulation of viral protein synthesis						bhm	2016-02-17T15:53:15Z						biological_process											owl:Class	
GO:1901289	biolink:NamedThing	succinyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of succinyl-CoA.	got7fsn_ti	succinyl-CoA breakdown|succinyl-CoA degradation|succinyl-CoA catabolism						yaf	2012-08-17T16:13:37Z						biological_process											owl:Class	
GO:1901973	biolink:NamedThing	proline binding	Binding to proline.	got7fsn_ti							pm	2013-02-26T14:58:01Z						molecular_function											owl:Class	
GO:0002821	biolink:NamedThing	positive regulation of adaptive immune response	Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.	got7fsn_ti	stimulation of adaptive immune response|upregulation of adaptive immune response|activation of adaptive immune response|up regulation of adaptive immune response|up-regulation of adaptive immune response													biological_process											owl:Class	
GO:1904971	biolink:NamedThing	regulation of viral translation	Any process that modulates the frequency, rate or extent of viral translation.	got7fsn_ti	regulation of viral protein biosynthetic process|regulation of viral protein biosynthesis|regulation of viral protein anabolism|regulation of viral protein synthesis|regulation of viral protein formation						bhm	2016-02-17T15:52:59Z						biological_process											owl:Class	
GO:1901123	biolink:NamedThing	bacitracin A catabolic process	The chemical reactions and pathways resulting in the breakdown of bacitracin A.	got7fsn_ti	bacitracin A breakdown|bacitracin A catabolism|bacitracin A degradation						yaf	2012-07-11T03:16:20Z						biological_process											owl:Class	
GO:1901169	biolink:NamedThing	3-chlorocatechol biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-chlorocatechol.	got7fsn_ti	3-chlorocatechol anabolism|3-chlorocatechol biosynthesis|3-chlorocatechol synthesis|3-chlorocatechol formation						yaf	2012-07-19T09:33:45Z						biological_process											owl:Class	
GO:0140321	biolink:NamedThing	negative regulation by symbiont of host autophagy	Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti							pg	2019-04-03T09:21:48Z						biological_process											owl:Class	
GO:0045774	biolink:NamedThing	negative regulation of beta 2 integrin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.	got7fsn_ti	negative regulation of beta 2 integrin anabolism|down regulation of beta 2 integrin biosynthetic process|downregulation of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin formation|inhibition of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin synthesis|down-regulation of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin biosynthesis													biological_process											owl:Class	
GO:0090207	biolink:NamedThing	regulation of triglyceride metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.	got7fsn_ti							tb	2009-12-23T10:35:06Z						biological_process											owl:Class	
GO:1900870	biolink:NamedThing	tatiopterin biosynthetic process	The chemical reactions and pathways resulting in the formation of tatiopterin.	got7fsn_ti	tatiopterin formation|tatiopterin biosynthesis|tatiopterin synthesis|tatiopterin anabolism						tt	2012-06-12T04:44:19Z						biological_process											owl:Class	
GO:0043611	biolink:NamedThing	isoprene metabolic process	The chemical reactions and pathways involving isoprene, C5H8.	got7fsn_ti	2-methyl-1,3-butadiene metabolic process|hemiterpene metabolic process|isoprene metabolism|hemiterpene metabolism|2-methyl-1,3-butadiene metabolism													biological_process											owl:Class	
GO:1904596	biolink:NamedThing	regulation of connective tissue replacement involved in inflammatory response wound healing	Any process that modulates the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.	got7fsn_ti	regulation of connective tissue replacement during inflammatory response|regulation of fibrosis during inflammatory response						krc	2015-08-25T20:52:24Z						biological_process											owl:Class	
GO:0019505	biolink:NamedThing	resorcinol metabolic process	The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic.	got7fsn_ti	resorcinol metabolism|1,3-benzenediol metabolism|1,3-benzenediol metabolic process|1,3-dihydroxybenzene metabolic process|1,3-dihydroxybenzene metabolism											MetaCyc:P343-PWY		biological_process											owl:Class	
GO:0002652	biolink:NamedThing	regulation of tolerance induction dependent upon immune response	Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.	got7fsn_ti	regulation of immune response-dependent tolerance induction													biological_process											owl:Class	
GO:0098964	biolink:NamedThing	anterograde dendritic transport of messenger ribonucleoprotein complex	The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse.	got7fsn_ti	anterograde dendritic transport of mRNA RNP complex													biological_process											owl:Class	
GO:0140021	biolink:NamedThing	mitochondrial ADP transmembrane transport	The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							pg	2017-04-10T15:14:34Z						biological_process											owl:Class	
GO:0106216	biolink:NamedThing	positive regulation of vesicle fusion with Golgi apparatus	Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus.	got7fsn_ti							hjd	2019-06-27T15:20:59Z						biological_process											owl:Class	
GO:0033498	biolink:NamedThing	galactose catabolic process via D-galactonate	The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate.	got7fsn_ti	galactose catabolism via D-galactonate|galactose degradation via D-galactonate|galactose breakdown via D-galactonate											MetaCyc:GALDEG-PWY		biological_process											owl:Class	
GO:0060500	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in lung bud formation	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0060431				True				biological_process											owl:Class	
GO:0140544	biolink:NamedThing	septin collar organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar.	got7fsn_ti	cellular bud neck septin hourglass organization	https://github.com/geneontology/go-ontology/issues/19534					pg	2020-11-10T13:47:48Z						biological_process											owl:Class	
GO:0033671	biolink:NamedThing	negative regulation of NAD+ kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.	got7fsn_ti	NAD+ kinase inhibitor|down regulation of NAD+ kinase activity|down-regulation of NAD+ kinase activity|downregulation of NAD+ kinase activity|inhibition of NAD+ kinase activity													biological_process											owl:Class	
GO:1901635	biolink:NamedThing	obsolete regulation of maintenance of presynaptic active zone structure	OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of presynaptic active zone structure.	got7fsn_ti	regulation of maintenance of presynaptic active zone structure				This term was obsoleted at the TermGenie Gatekeeper stage.		ans	2012-11-15T14:17:03Z		True				biological_process											owl:Class	
GO:0030355	biolink:NamedThing	obsolete small nucleolar ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	snoRNP|small nucleolar ribonucleoprotein			GO:0005732	This term was made obsolete because it describes a cellular component rather than a molecular function.					True				molecular_function											owl:Class	
GO:0010716	biolink:NamedThing	negative regulation of extracellular matrix disassembly	Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.	got7fsn_ti	downregulation of extracellular matrix disassembly|inhibition of extracellular matrix disassembly|down-regulation of extracellular matrix disassembly|down regulation of extracellular matrix disassembly|negative regulation of extracellular matrix breakdown|negative regulation of extracellular matrix degradation													biological_process											owl:Class	
GO:0060750	biolink:NamedThing	epithelial cell proliferation involved in mammary gland duct elongation	The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth.	got7fsn_ti							dph	2009-06-22T10:58:12Z						biological_process											owl:Class	
GO:0033351	biolink:NamedThing	UDP-D-apiose metabolic process	The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-D-apiose metabolism													biological_process											owl:Class	
GO:1900115	biolink:NamedThing	extracellular regulation of signal transduction	Any regulation of signal transduction that takes place in the extracellular region.	got7fsn_ti	regulation of signalling pathway in extracellular region|regulation of signaling pathway in extracellular region						bf	2012-02-22T10:21:48Z						biological_process											owl:Class	
GO:1902041	biolink:NamedThing	regulation of extrinsic apoptotic signaling pathway via death domain receptors	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.	got7fsn_ti	regulation of death receptor-mediated apoptosis						lb	2013-04-03T07:16:59Z						biological_process											owl:Class	
OBO:OBA_0000113	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902609	biolink:NamedThing	(R)-2-hydroxy-alpha-linolenic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid.	got7fsn_ti	(R)-2-hydroxy-alpha-linolenic acid formation|(R)-2-hydroxy-alpha-linolenic acid synthesis|2-hydroxy-octadecatrienoic acid biosynthesis|(R)-2-hydroxy-alpha-linolenic acid anabolism|(R)-2-hydroxy-alpha-linolenic acid biosynthesis						tb	2014-01-08T01:14:03Z						biological_process											owl:Class	
GO:0003200	biolink:NamedThing	endocardial cushion to mesenchymal transition involved in heart chamber septation	A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum.	got7fsn_ti							dph	2009-10-08T01:34:31Z						biological_process											owl:Class	
GO:0033121	biolink:NamedThing	regulation of purine nucleotide catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.	got7fsn_ti	regulation of purine nucleotide breakdown|regulation of purine nucleotide catabolism|regulation of purine nucleotide degradation													biological_process											owl:Class	
GO:0010780	biolink:NamedThing	meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti														biological_process											owl:Class	
GO:0060800	biolink:NamedThing	regulation of cell differentiation involved in embryonic placenta development	Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.	got7fsn_ti							dph	2009-08-06T01:20:25Z						biological_process											owl:Class	
GO:0046371	biolink:NamedThing	dTDP-mannose metabolic process	The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.	got7fsn_ti	dTDP-mannose metabolism													biological_process											owl:Class	
CHEBI:32504	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045658	biolink:NamedThing	regulation of neutrophil differentiation	Any process that modulates the frequency, rate or extent of neutrophil differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1900384	biolink:NamedThing	regulation of flavonol biosynthetic process	Any process that modulates the frequency, rate or extent of flavonol biosynthetic process.	got7fsn_ti							tb	2012-04-17T10:22:49Z						biological_process											owl:Class	
GO:0038015	biolink:NamedThing	positive regulation of insulin receptor signaling pathway by insulin receptor internalization	Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane.	got7fsn_ti	positive regulation of insulin receptor signalling pathway by insulin receptor internalization						bf	2011-06-23T04:20:11Z						biological_process											owl:Class	
GO:1905527	biolink:NamedThing	negative regulation of Golgi lumen acidification	Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification.	got7fsn_ti	down regulation of Golgi lumen acidification|downregulation of Golgi lumen acidification|down-regulation of Golgi lumen acidification|inhibition of Golgi lumen acidification						dph	2016-10-05T13:16:33Z						biological_process											owl:Class	
CHEBI:17478	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904996	biolink:NamedThing	positive regulation of leukocyte adhesion to vascular endothelial cell	Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.	got7fsn_ti	activation of leukocyte adhesion to vascular endothelial cell|up-regulation of leukocyte adhesion to vascular endothelial cell|up regulation of leukocyte adhesion to vascular endothelial cell|upregulation of leukocyte adhesion to vascular endothelial cell						bc	2016-03-01T10:59:22Z						biological_process											owl:Class	
GO:0090069	biolink:NamedThing	regulation of ribosome biogenesis	Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.	got7fsn_ti							tb	2009-09-11T10:32:17Z						biological_process											owl:Class	
GO:0090315	biolink:NamedThing	negative regulation of protein targeting to membrane	Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.	got7fsn_ti							tb	2010-04-16T03:42:22Z						biological_process											owl:Class	
GO:1901084	biolink:NamedThing	pyrrolizidine alkaloid catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrrolizidine alkaloid.	got7fsn_ti	pyrrolizidine alkaloid degradation|pyrrolizidine alkaloid breakdown|pyrrolizidine alkaloid catabolism						yaf	2012-07-05T10:28:20Z						biological_process											owl:Class	
GO:1900830	biolink:NamedThing	obsolete D-tyrosine biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of D-tyrosine.	got7fsn_ti	D-tyrosine formation|D-tyrosine biosynthesis|D-tyrosine anabolism|D-tyrosine synthesis	https://github.com/geneontology/go-ontology/issues/20583			This term was obsoleted because there is no evidence that this process exists.		se	2012-06-06T09:27:31Z		True				biological_process											owl:Class	
GO:0006686	biolink:NamedThing	sphingomyelin biosynthetic process	The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.	got7fsn_ti	sphingomyelin anabolism|sphingomyelin formation|sphingomyelin synthesis|sphingomyelin biosynthesis													biological_process											owl:Class	
GO:0045331	biolink:NamedThing	obsolete coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity	OBSOLETE. Catalysis of the reaction: coenzyme-M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + H2 = coenzyme-M + N-(7-mercaptoheptanoyl)threonine O3-phosphate.	got7fsn_ti	coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|heterodisulfide reductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulphide hydrogenase activity				This term was made obsolete because it represents two activities.	GO:0051912|GO:0051911				True				molecular_function											owl:Class	
GO:1904688	biolink:NamedThing	regulation of cytoplasmic translational initiation	Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.	got7fsn_ti							dos	2015-09-25T14:39:38Z						biological_process											owl:Class	
CHEBI:25706	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042418	biolink:NamedThing	epinephrine biosynthetic process	The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	got7fsn_ti	adrenaline biosynthesis|adrenaline biosynthetic process|epinephrine anabolism|epinephrine formation|epinephrine biosynthesis|epinephrine synthesis													biological_process											owl:Class	
GO:0140268	biolink:NamedThing	endoplasmic reticulum-plasma membrane contact site	A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.	got7fsn_ti	ER-PM contact site|ER-plasma membrane contact site|endoplasmic reticulum-plasma membrane contact junction|EPCS						pg	2018-09-26T09:29:41Z						cellular_component											owl:Class	
UBERON:0006860	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0062156	biolink:NamedThing	mitochondrial ATP-gated potassium channel activity	Enables the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.	got7fsn_ti	mitochondrial potassium channel activity|mitoK-ATP activity						dph	2019-09-20T16:07:07Z						molecular_function											owl:Class	
GO:0033198	biolink:NamedThing	response to ATP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.	got7fsn_ti	response to adenosine triphosphate|response to adenosine 5'-triphosphate													biological_process											owl:Class	
GO:1902008	biolink:NamedThing	negative regulation of toxin transport	Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport.	got7fsn_ti	down regulation of toxin transport|downregulation of toxin transport|inhibition of toxin transport|down-regulation of toxin transport						dph	2013-03-22T12:54:00Z						biological_process											owl:Class	
GO:0045934	biolink:NamedThing	negative regulation of nucleobase-containing compound metabolic process	Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.	got7fsn_ti	inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process													biological_process											owl:Class	
CHEBI:84118	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033519	biolink:NamedThing	phytyl diphosphate metabolic process	The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.	got7fsn_ti	phytyl diphosphate metabolism													biological_process											owl:Class	
GO:1904609	biolink:NamedThing	cellular response to monosodium L-glutamate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus.	got7fsn_ti							sl	2015-08-27T18:43:14Z						biological_process											owl:Class	
GO:2000973	biolink:NamedThing	regulation of pro-B cell differentiation	Any process that modulates the frequency, rate or extent of pro-B cell differentiation.	got7fsn_ti	regulation of pro-B lymphocyte differentiation|regulation of pro-B cell development						yaf	2011-08-02T03:05:45Z						biological_process											owl:Class	
GO:0004626	biolink:NamedThing	obsolete cytosolic phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	got7fsn_ti	cytosolic phospholipase A2 activity				This term was made obsolete because it represents component and function information.	GO:0004623|GO:0005829				True				molecular_function											owl:Class	
GO:0072755	biolink:NamedThing	cellular response to benomyl	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.	got7fsn_ti							mah	2012-11-07T12:06:58Z						biological_process											owl:Class	
GO:1902319	biolink:NamedThing	DNA strand elongation involved in nuclear cell cycle DNA replication	Any DNA strand elongation that is involved in nuclear cell cycle DNA replication.	got7fsn_ti	DNA strand elongation involved in DNA replication involved in S-phase|DNA strand elongation involved in DNA replication during S phase|DNA strand elongation involved in DNA replication involved in S phase						jl	2013-07-23T14:00:41Z						biological_process											owl:Class	
GO:1900907	biolink:NamedThing	positive regulation of hexadecanal metabolic process	Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process.	got7fsn_ti	positive regulation of hexadecanal metabolism|up regulation of hexadecanal metabolism|up regulation of hexadecanal metabolic process|up-regulation of hexadecanal metabolism|activation of hexadecanal metabolic process|activation of hexadecanal metabolism|upregulation of hexadecanal metabolic process|upregulation of hexadecanal metabolism|up-regulation of hexadecanal metabolic process						tt	2012-06-13T03:36:02Z						biological_process											owl:Class	
GO:0033248	biolink:NamedThing	negative regulation of penicillin catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti	negative regulation of penicillin breakdown|negative regulation of penicillin catabolism|negative regulation of penicillin degradation													biological_process											owl:Class	
CHEBI:60935	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901181	biolink:NamedThing	negative regulation of cellular response to caffeine	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine.	got7fsn_ti	downregulation of cellular response to caffeine|down-regulation of cellular response to caffeine|down regulation of cellular response to caffeine|inhibition of cellular response to caffeine						al	2012-07-19T04:11:46Z						biological_process											owl:Class	
GO:0043075	biolink:NamedThing	obsolete sperm cell nucleus (sensu Magnoliophyta)	OBSOLETE. The nucleus of a plant pollen cell, the male gamete, and its descendents.	got7fsn_ti	pollen germ cell nucleus|sperm cell nucleus (sensu Magnoliophyta)|pollen germ-cell nucleus				This term was made obsolete because the definition was incorrect.	GO:0048555				True				cellular_component											owl:Class	
GO:0048385	biolink:NamedThing	regulation of retinoic acid receptor signaling pathway	Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.	got7fsn_ti	regulation of retinoic acid receptor signalling pathway|regulation of RAR signaling pathway													biological_process											owl:Class	
GO:0099612	biolink:NamedThing	protein localization to axon	A process in which a protein is transported to or maintained in a location within an axon.	got7fsn_ti														biological_process											owl:Class	
GO:0061608	biolink:NamedThing	nuclear import signal receptor activity	Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.	got7fsn_ti	importin activity	https://github.com/geneontology/go-ontology/issues/14336					dph	2014-03-03T07:58:18Z						molecular_function											owl:Class	
GO:0008620	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051113	biolink:NamedThing	obsolete enzyme active site formation via 1'-(phospho-5'-adenosine)-L-histidine	OBSOLETE. The transient adenylylation of peptidyl-histidine to form 1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:15182206.					True		RESID:AA0371		biological_process											owl:Class	
GO:0055112	biolink:NamedThing	delamination involved in gastrulation with mouth forming second	The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0001167	biolink:NamedThing	obsolete RNA polymerase I transcription factor activity, sequence-specific DNA binding	OBSOLETE. Binding to a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.	got7fsn_ti	sequence-specific DNA binding RNA polymerase I transcription factor activity	https://github.com/geneontology/go-ontology/issues/15787			This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2011-02-03T04:07:46Z		True				molecular_function											owl:Class	
GO:1902615	biolink:NamedThing	immune response involved in response to exogenous dsRNA	Any immune response that is involved in response to exogenous dsRNA.	got7fsn_ti	immune response involved in response to exogenous double-stranded RNA|immune response involved in response to viral dsRNA						tb	2014-01-10T01:29:25Z						biological_process											owl:Class	
GO:1901854	biolink:NamedThing	5,6,7,8-tetrahydrosarcinapterin catabolic process	The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin.	got7fsn_ti	5,6,7,8-tetrahydrosarcinapterin degradation|5,6,7,8-tetrahydrosarcinapterin catabolism|5,6,7,8-tetrahydrosarcinapterin breakdown						yaf	2013-01-28T11:48:01Z						biological_process											owl:Class	
GO:0005580	biolink:NamedThing	obsolete membrane attack complex protein alphaM chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	membrane attack complex protein alphaM chain			GO:0005579	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
CHEBI:18230	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002662	biolink:NamedThing	negative regulation of B cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction.	got7fsn_ti	downregulation of B cell tolerance induction|down-regulation of B cell tolerance induction|down regulation of B cell tolerance induction|negative regulation of B lymphocyte tolerance induction|negative regulation of B-cell tolerance induction|inhibition of B cell tolerance induction|negative regulation of B-lymphocyte tolerance induction													biological_process											owl:Class	
GO:0044424	biolink:NamedThing	obsolete intracellular part	OBSOLETE. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005622				True				cellular_component											owl:Class	
GO:0051334	biolink:NamedThing	meiosis I nuclear membrane reassembly	The reformation of the nuclear membranes during meiosis I.	got7fsn_ti	meiosis I nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636												biological_process											owl:Class	
GO:0004050	biolink:NamedThing	obsolete apyrase activity	OBSOLETE. Catalysis of the reaction: ATP + 2 H2O = AMP + 2 phosphate.	got7fsn_ti	apyrase activity				This term was made obsolete because it represents a gene product which can catalyze two reactions.	GO:0017110|GO:0017111				True				molecular_function											owl:Class	
GO:0050857	biolink:NamedThing	positive regulation of antigen receptor-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.	got7fsn_ti	up-regulation of antigen receptor-mediated signaling pathway|activation of antigen receptor-mediated signaling pathway|up regulation of antigen receptor-mediated signaling pathway|stimulation of antigen receptor-mediated signaling pathway|upregulation of antigen receptor-mediated signaling pathway|positive regulation of antigen receptor mediated signalling pathway													biological_process											owl:Class	
GO:0009167	biolink:NamedThing	purine ribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine ribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:1905630	biolink:NamedThing	response to glyceraldehyde	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.	got7fsn_ti							sl	2016-10-31T16:32:19Z						biological_process											owl:Class	
CHEBI:37530	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0085002	biolink:NamedThing	obsolete interaction with host mediated by secreted substance released by symbiont from symbiotic structure	OBSOLETE. An interaction with the host organism mediated by a symbiont secreted substance released by specialized structures generated in either organisms as a result of the symbiotic interaction. The term host is used for the larger (macro) of the two members of a symbiosis.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T02:38:10Z		True				biological_process											owl:Class	
GO:0003969	biolink:NamedThing	obsolete RNA editase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	RNA editase activity				This term was made obsolete because it describes a biological process.					True				molecular_function											owl:Class	
GO:1901102	biolink:NamedThing	gramicidin S catabolic process	The chemical reactions and pathways resulting in the breakdown of gramicidin S.	got7fsn_ti	gramicidin S breakdown|gramicidin S degradation|gramicidin S catabolism						yaf	2012-07-11T02:30:52Z						biological_process											owl:Class	
GO:1904722	biolink:NamedThing	obsolete positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	OBSOLETE. Any process that activates or increases the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.	got7fsn_ti	upregulation of XBP1 mRNA cleavage|positive regulation of HAC1 mRNA cleavage|up-regulation of IRE1-mediated XBP-1 mRNA cleavage|activation of HAC1 mRNA cleavage|up-regulation of HAC1 mRNA cleavage|positive regulation of HAC1-type intron splice site recognition and cleavage|upregulation of IRE1-mediated XBP-1 mRNA cleavage|up-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|positive regulation of IRE1-mediated XBP-1 mRNA cleavage|up-regulation of HAC1-type intron splice site recognition and cleavage|upregulation of HAC1-type intron splice site recognition and cleavage|activation of HAC1-type intron splice site recognition and cleavage|activation of XBP1 mRNA cleavage|up regulation of IRE1-mediated XBP-1 mRNA cleavage|activation of IRE1-mediated XBP-1 mRNA cleavage|upregulation of HAC1 mRNA cleavage|positive regulation of XBP1 mRNA cleavage|up-regulation of XBP1 mRNA cleavage|activation of mRNA endonucleolytic cleavage involved in unfolded protein response|up regulation of HAC1 mRNA cleavage|upregulation of mRNA endonucleolytic cleavage involved in unfolded protein response|up regulation of XBP1 mRNA cleavage|up regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|up regulation of HAC1-type intron splice site recognition and cleavage				The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted.	GO:1903896	bf	2015-10-08T14:53:02Z		True				biological_process											owl:Class	
GO:0070786	biolink:NamedThing	positive regulation of growth of unicellular organism as a thread of attached cells	Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.	got7fsn_ti							mah	2009-07-07T02:39:48Z						biological_process											owl:Class	
GO:0033132	biolink:NamedThing	negative regulation of glucokinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.	got7fsn_ti	down-regulation of glucokinase activity|glucokinase inhibitor|down regulation of glucokinase activity|downregulation of glucokinase activity|inhibition of glucokinase activity													biological_process											owl:Class	
GO:0043940	biolink:NamedThing	regulation of sexual sporulation resulting in formation of a cellular spore	Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.	got7fsn_ti														biological_process											owl:Class	
GO:0045937	biolink:NamedThing	positive regulation of phosphate metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.	got7fsn_ti	positive regulation of phosphate metabolism|upregulation of phosphate metabolic process|activation of phosphate metabolic process|stimulation of phosphate metabolic process|up regulation of phosphate metabolic process|up-regulation of phosphate metabolic process													biological_process											owl:Class	
GO:0061934	biolink:NamedThing	regulation of adenine biosynthetic process	Any process that modulates the frequency, rate or extent of an adenine biosynthetic process.	got7fsn_ti							dph	2017-09-05T14:58:46Z						biological_process											owl:Class	
GO:1901085	biolink:NamedThing	pyrrolizidine alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid.	got7fsn_ti	pyrrolizidine alkaloid synthesis|pyrrolizidine alkaloid formation|pyrrolizidine alkaloid anabolism|pyrrolizidine alkaloid biosynthesis						yaf	2012-07-05T10:28:28Z						biological_process											owl:Class	
GO:1900268	biolink:NamedThing	regulation of reverse transcription	Any process that modulates the frequency, rate or extent of reverse transcription.	got7fsn_ti							tb	2012-04-03T11:13:26Z						biological_process											owl:Class	
GO:0086075	biolink:NamedThing	gap junction channel activity involved in cardiac conduction electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	got7fsn_ti							dph	2011-11-22T10:08:29Z						molecular_function											owl:Class	
GO:0009497	biolink:NamedThing	obsolete 3Fe-4S/4Fe-4S electron transfer carrier	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	3Fe-4S/4Fe-4S electron transfer carrier			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:1903617	biolink:NamedThing	positive regulation of mitotic cytokinesis, site selection	Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, site selection.	got7fsn_ti							vw	2014-11-19T10:52:25Z						biological_process											owl:Class	
GO:0071531	biolink:NamedThing	obsolete Rel homology domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a Rel homology domain (RHD) interaction.	got7fsn_ti	RHD domain-mediated complex assembly				This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T02:16:39Z		True				biological_process											owl:Class	
GO:0052007	biolink:NamedThing	obsolete biosynthesis by symbiont of substance in host	OBSOLETE. The chemical reactions and pathways performed by an organism in its host resulting in the formation of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	biosynthesis by organism of substance in host	https://github.com/geneontology/go-ontology/issues/18787			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0022841	biolink:NamedThing	potassium ion leak channel activity	Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.	got7fsn_ti														molecular_function											owl:Class	
GO:0008724	biolink:NamedThing	obsolete DNA topoisomerase IV activity	OBSOLETE. Catalysis of the ATP-independent breakage of DNA, followed by passage and rejoining. It also catalyzes the relaxation of supercoiled DNA, and the decatenation and unknotting of DNA in vivo.	got7fsn_ti	DNA topoisomerase IV activity			GO:0003918	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0008259	biolink:NamedThing	obsolete transforming growth factor beta ligand binding to type I receptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transforming growth factor beta ligand binding to type I receptor|TGF-beta ligand binding to type I receptor|TGFbeta ligand binding to type I receptor				This term was made obsolete because it represents a function.	GO:0005160|GO:0005025|GO:0050431				True				biological_process											owl:Class	
GO:0032675	biolink:NamedThing	regulation of interleukin-6 production	Any process that modulates the frequency, rate, or extent of interleukin-6 production.	got7fsn_ti	regulation of IL-6 production|regulation of interleukin-6 biosynthetic process										GO:0045408			biological_process											owl:Class	
GO:1904383	biolink:NamedThing	response to sodium phosphate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.	got7fsn_ti							sl	2015-06-23T16:55:07Z						biological_process											owl:Class	
GO:1902807	biolink:NamedThing	negative regulation of cell cycle G1/S phase transition	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.	got7fsn_ti	down regulation of cell cycle G1/S phase transition|inhibition of cell cycle G1/S phase transition|downregulation of cell cycle G1/S phase transition|down-regulation of cell cycle G1/S phase transition						jl	2014-03-26T16:36:20Z						biological_process											owl:Class	
GO:2001044	biolink:NamedThing	regulation of integrin-mediated signaling pathway	Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway.	got7fsn_ti	regulation of integrin-mediated signalling pathway						bf	2011-08-31T03:49:11Z						biological_process											owl:Class	
GO:2000490	biolink:NamedThing	negative regulation of hepatic stellate cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation.	got7fsn_ti							bf	2011-03-14T03:49:18Z						biological_process											owl:Class	
GO:2000893	biolink:NamedThing	cellotriose metabolic process	The chemical reactions and pathways involving a cellotriose.	got7fsn_ti	cellotriose metabolism						jl	2011-07-28T02:02:44Z						biological_process											owl:Class	
GO:0009971	biolink:NamedThing	anastral spindle assembly involved in male meiosis	The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells.	got7fsn_ti														biological_process											owl:Class	
GO:0060381	biolink:NamedThing	positive regulation of single-stranded telomeric DNA binding	Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding.	got7fsn_ti	positive regulation of telomeric ssDNA binding													biological_process											owl:Class	
GO:1900271	biolink:NamedThing	regulation of long-term synaptic potentiation	Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.	got7fsn_ti	regulation of LTP|regulation of long-term potentiation						rl	2012-04-04T07:17:13Z						biological_process											owl:Class	
GO:0009494	biolink:NamedThing	obsolete chloroplast-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	chloroplast-type ferredoxin			GO:0009055	This term was made obsolete because it does not represent a function.					True				molecular_function											owl:Class	
GO:1903049	biolink:NamedThing	negative regulation of acetylcholine-gated cation channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity.	got7fsn_ti	down-regulation of acetylcholine-gated cation channel activity|down regulation of acetylcholine-gated cation channel activity|downregulation of acetylcholine-gated cation channel activity|inhibition of acetylcholine-gated cation channel activity						bf	2014-05-22T14:47:00Z						biological_process											owl:Class	
GO:1905523	biolink:NamedThing	positive regulation of macrophage migration	Any process that activates or increases the frequency, rate or extent of macrophage migration.	got7fsn_ti	upregulation of macrophage migration|up regulation of macrophage migration|activation of macrophage migration|up-regulation of macrophage migration						sl	2016-10-03T15:29:21Z						biological_process											owl:Class	
GO:0051254	biolink:NamedThing	positive regulation of RNA metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.	got7fsn_ti	up-regulation of RNA metabolic process|stimulation of RNA metabolic process|up regulation of RNA metabolic process|activation of RNA metabolic process|positive regulation of RNA metabolism|upregulation of RNA metabolic process													biological_process											owl:Class	
GO:0003788	biolink:NamedThing	obsolete actin monomer sequestering activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	actin monomer sequestering activity			GO:0042989	This term was made obsolete because sequestering is a process, not an activity.					True				molecular_function											owl:Class	
GO:0046851	biolink:NamedThing	negative regulation of bone remodeling	Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.	got7fsn_ti	down regulation of bone remodeling|downregulation of bone remodeling|inhibition of bone remodeling|down-regulation of bone remodeling													biological_process											owl:Class	
GO:2001020	biolink:NamedThing	regulation of response to DNA damage stimulus	Any process that modulates the frequency, rate or extent of response to DNA damage stimulus.	got7fsn_ti	regulation of DNA damage response|regulation of response to genotoxic stress|regulation of cellular DNA damage response|regulation of cellular response to DNA damage stimulus						yaf	2011-08-19T10:20:25Z						biological_process											owl:Class	
GO:2000913	biolink:NamedThing	negative regulation of galactoglucomannan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process.	got7fsn_ti	negative regulation of galactoglucomannan catabolism						tt	2011-07-29T07:51:41Z						biological_process											owl:Class	
GO:0098565	biolink:NamedThing	lumenal side of endosome membrane	The side (leaflet) of the endosome membrane that faces the lumen.	got7fsn_ti	internal leaflet of endosome membrane|internal side of endosome membrane													cellular_component											owl:Class	
GO:1902804	biolink:NamedThing	negative regulation of synaptic vesicle transport	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport.	got7fsn_ti	down-regulation of synaptic vesicle transport|down regulation of synaptic vesicle fission|downregulation of synaptic vesicle fission|down regulation of synaptic vesicle transport|down-regulation of synaptic vesicle fission|inhibition of synaptic vesicle fission|downregulation of synaptic vesicle fusion|inhibition of synaptic vesicle fusion|downregulation of synaptic vesicle transport|inhibition of synaptic vesicle transport|negative regulation of synaptic vesicle fusion|down-regulation of synaptic vesicle fusion|down regulation of synaptic vesicle fusion|negative regulation of synaptic vesicle fission						kmv	2014-03-25T14:56:40Z						biological_process											owl:Class	
GO:0042498	biolink:NamedThing	diacyl lipopeptide binding	Binding to a lipopeptide containing a nonprotein moiety consisting of two acyl groups.	got7fsn_ti	bacterial diacyl lipopeptide binding|bacterial diacyl lipoprotein binding|diacylated lipopeptide binding				Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.									molecular_function											owl:Class	
GO:0052492	biolink:NamedThing	obsolete negative regulation by host of symbiont signal transduction pathway	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative modulation by organism of symbiont signal transduction pathway|down regulation by host of symbiont signal transduction pathway|down-regulation by host of symbiont signal transduction pathway|inhibition by host of symbiont signal transduction pathway|downregulation by host of symbiont signal transduction pathway				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0046303	biolink:NamedThing	obsolete 2-nitropropane biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor.	got7fsn_ti	2-nitropropane biosynthesis|2-nitropropane formation|2-nitropropane synthesis|2-nitropropane anabolism|2-nitropropane biosynthetic process			GO:0018938	This term was made obsolete because 2-nitropropane is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0016024	biolink:NamedThing	CDP-diacylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.	got7fsn_ti	CDP-diacylglycerol anabolism|CDP-diacylglycerol synthesis|CDP-diacylglycerol biosynthesis|CDP-diacylglycerol formation													biological_process											owl:Class	
GO:0060752	biolink:NamedThing	intestinal phytosterol absorption	Any process in which phytosterols are taken up from the contents of the intestine.	got7fsn_ti							dph	2009-06-22T02:08:43Z						biological_process											owl:Class	
GO:0015009	biolink:NamedThing	corrin metabolic process	The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.	got7fsn_ti	corrin metabolism													biological_process											owl:Class	
GO:0070233	biolink:NamedThing	negative regulation of T cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.	got7fsn_ti	down-regulation of T cell apoptosis|negative regulation of T-lymphocyte apoptosis|negative regulation of T-cell apoptosis|down regulation of T cell apoptosis|negative regulation of programmed cell death of T cells by apoptosis|negative regulation of T lymphocyte apoptosis|downregulation of T cell apoptosis|inhibition of T cell apoptosis|negative regulation of T cell apoptosis													biological_process											owl:Class	
GO:1904447	biolink:NamedThing	folate import across plasma membrane	The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	folic acid import across plasma membrane|folate import into cell						hal	2015-07-07T15:32:33Z						biological_process											owl:Class	
GO:2000326	biolink:NamedThing	obsolete negative regulation of nuclear receptor transcription coactivator activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.	got7fsn_ti	negative regulation of ligand-dependent nuclear receptor transcription co-activator activity|negative regulation of ligand-dependent nuclear receptor transcription coactivator activity				This term was obsoleted because it represents a molecular function.	GO:0140536	vk	2011-01-18T06:30:03Z		True				biological_process											owl:Class	
GO:0086076	biolink:NamedThing	gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	got7fsn_ti	gap junction channel activity involved in atrial cardiomyocyte-AV node cell electrical coupling|gap junction channel activity involved in atrial cardiomyocyte-atrioventricular node cell electrical coupling						dph	2011-11-22T10:26:27Z						molecular_function											owl:Class	
GO:0030213	biolink:NamedThing	hyaluronan biosynthetic process	The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.	got7fsn_ti	hyaluronan biosynthesis|hyaluronan synthesis|hyaluronan formation|hyaluronan anabolism													biological_process											owl:Class	
GO:0090072	biolink:NamedThing	obsolete positive regulation of sodium ion transport via voltage-gated sodium channel activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of sodium ions via the activity of voltage-gated sodium channels.	got7fsn_ti	positive regulation of sodium ion transport via voltage-gated sodium channel activity				This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0005248	tb	2009-09-11T10:46:13Z		True				biological_process											owl:Class	
GO:0015997	biolink:NamedThing	obsolete ubiquinone biosynthetic process monooxygenase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ubiquinone anabolism monooxygenase activity|coenzyme Q biosynthetic process monooxygenase activity|ubiquinone formation monooxygenase activity|coenzyme Q biosynthesis monooxygenase activity|ubiquinone biosynthetic process monooxygenase activity|ubiquinone synthesis monooxygenase activity				This term was made obsolete because it incorporates biological process information.					True				molecular_function											owl:Class	
GO:0014710	biolink:NamedThing	negative regulation of somitomeric trunk muscle development	Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	got7fsn_ti														biological_process											owl:Class	
GO:1903326	biolink:NamedThing	regulation of tRNA metabolic process	Any process that modulates the frequency, rate or extent of tRNA metabolic process.	got7fsn_ti	regulation of tRNA metabolism						vw	2014-08-18T13:08:50Z						biological_process											owl:Class	
GO:0090514	biolink:NamedThing	L-tyrosine transmembrane import into vacuole	The directed movement of L-tyrosine into the vacuole across the vacuolar membrane.	got7fsn_ti							tb	2012-12-14T11:25:52Z						biological_process											owl:Class	
GO:1904883	biolink:NamedThing	negative regulation of telomerase catalytic core complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly.	got7fsn_ti	negative regulation of TERT-TERC complex formation|down-regulation of telomerase catalytic core complex assembly|negative regulation of telomerase catalytic core complex formation|down-regulation of TERT-TERC complex assembly|down-regulation of telomerase catalytic core complex formation|inhibition of TERT-TERC complex formation|inhibition of telomerase catalytic core complex assembly|down-regulation of TERT-TERC complex formation|negative regulation of TERT-TERC complex assembly|downregulation of telomerase catalytic core complex formation|inhibition of TERT-TERC complex assembly|downregulation of telomerase catalytic core complex assembly|inhibition of telomerase catalytic core complex formation|down regulation of telomerase catalytic core complex formation|down regulation of TERT-TERC complex formation|downregulation of TERT-TERC complex formation|down regulation of telomerase catalytic core complex assembly|down regulation of TERT-TERC complex assembly|downregulation of TERT-TERC complex assembly						rph	2016-01-05T10:36:09Z						biological_process											owl:Class	
GO:1900283	biolink:NamedThing	negative regulation of cellobiose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process.	got7fsn_ti	inhibition of cellobiose catabolic process|downregulation of cellobiose catabolism|negative regulation of cellobiose catabolism|down-regulation of cellobiose catabolism|inhibition of cellobiose catabolism|down regulation of cellobiose catabolic process|down regulation of cellobiose catabolism|down-regulation of cellobiose catabolic process|downregulation of cellobiose catabolic process						tt	2012-04-05T12:29:00Z						biological_process											owl:Class	
GO:0150165	biolink:NamedThing	miRNA-mediated inhibition of transcription by RNA polymerase II	Any process mediated by a microRNA (miRNA) that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti							bc	2020-01-14T12:21:12Z						biological_process											owl:Class	
GO:1903880	biolink:NamedThing	17alpha-hydroxyprogesterone binding	Binding to 17alpha-hydroxyprogesterone.	got7fsn_ti							mr	2015-02-06T16:03:22Z						molecular_function											owl:Class	
GO:0034176	biolink:NamedThing	negative regulation of toll-like receptor 12 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway.	got7fsn_ti	negative regulation of TLR12 signaling pathway|negative regulation of toll-like receptor 12 signalling pathway													biological_process											owl:Class	
GO:2000346	biolink:NamedThing	negative regulation of hepatocyte proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.	got7fsn_ti							mah	2011-02-03T10:27:20Z						biological_process											owl:Class	
GO:0051229	biolink:NamedThing	meiotic spindle disassembly	The controlled breakdown of the spindle during a meiotic cell cycle.	got7fsn_ti	spindle disassembly during meiosis|meiotic spindle breakdown|spindle breakdown during meiosis|meiotic spindle degradation|spindle degradation during meiosis|meiotic spindle catabolism													biological_process											owl:Class	
GO:0045826	biolink:NamedThing	obsolete positive regulation of intermediate filament polymerization and/or depolymerization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization and/or depolymerization.	got7fsn_ti	positive regulation of intermediate filament polymerization and/or depolymerization				This term was made obsolete because it has been split.	GO:0030841|GO:0030844				True				biological_process											owl:Class	
GO:0048241	biolink:NamedThing	epinephrine transport	The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	adrenaline transport													biological_process											owl:Class	
GO:1904296	biolink:NamedThing	negative regulation of osmolarity-sensing cation channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity.	got7fsn_ti	inhibition of osmolarity-sensing cation channel activity|down-regulation of osmolarity-sensing cation channel activity|down regulation of osmolarity-sensing cation channel activity|downregulation of osmolarity-sensing cation channel activity						sl	2015-06-09T17:35:46Z						biological_process											owl:Class	
GO:1902641	biolink:NamedThing	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.	got7fsn_ti	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation						di	2014-01-21T17:54:14Z						biological_process											owl:Class	
GO:1905052	biolink:NamedThing	negative regulation of base-excision repair	Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair.	got7fsn_ti	downregulation of BER|down-regulation of BER|negative regulation of BER|inhibition of base-excision repair|downregulation of base-excision repair|down-regulation of base-excision repair|inhibition of BER|down regulation of base-excision repair|down regulation of BER						ah	2016-03-16T10:52:09Z						biological_process											owl:Class	
GO:0032769	biolink:NamedThing	negative regulation of monooxygenase activity	Any process that stops or reduces the activity of a monooxygenase.	got7fsn_ti	down-regulation of monooxygenase activity|inhibition of monooxygenase activity|down regulation of monooxygenase activity|downregulation of monooxygenase activity													biological_process											owl:Class	
GO:0044337	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of apoptotic process.	got7fsn_ti	canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis|canonical Wnt-activated signaling pathway involved in positive regulation of apoptotic process|canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process|canonical Wnt receptor signalling pathway involved in positive regulation of apoptosis						jl	2010-08-20T03:08:24Z						biological_process											owl:Class	
GO:0048107	biolink:NamedThing	4-amino-3-isothiazolidinone biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively.	got7fsn_ti	4-amino-3-isothiazolidinone synthesis|4-amino-3-isothiazolidinone biosynthesis|4-amino-3-isothiazolidinone anabolism|4-amino-3-isothiazolidinone formation													biological_process											owl:Class	
GO:1901498	biolink:NamedThing	response to tetralin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus.	got7fsn_ti							tt	2012-10-16T15:10:22Z						biological_process											owl:Class	
GO:0034041	biolink:NamedThing	ABC-type sterol transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).	got7fsn_ti	ATP-coupled sterol transmembrane transporter activity|sterol-transporting ATPase activity|ATPase-coupled sterol transmembrane transporter activity|ATP-dependent sterol transmembrane transporter activity													molecular_function											owl:Class	
GO:1903151	biolink:NamedThing	obsolete carbohydrate transmembrane transporter activity involved in carbohydrate import into cell	OBSOLETE. Any carbohydrate transmembrane transporter activity that is involved in carbohydrate import into cell.	got7fsn_ti	carbohydrate transmembrane transporter activity involved in carbohydrate import into cell|sugar transporter involved in carbohydrate import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:42Z		True				molecular_function											owl:Class	
GO:1901829	biolink:NamedThing	zeaxanthin bis(beta-D-glucoside) catabolic process	The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside).	got7fsn_ti	zeaxanthin bis(beta-D-glucoside) degradation|zeaxanthin diglucoside breakdown|zeaxanthin bis(beta-D-glucoside) catabolism|zeaxanthin diglucoside catabolism|zeaxanthin diglucoside degradation|zeaxanthin bis(beta-D-glucoside) breakdown						yaf	2013-01-22T12:32:06Z						biological_process											owl:Class	
GO:0098728	biolink:NamedThing	germline stem cell asymmetric division	The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.	got7fsn_ti														biological_process											owl:Class	
GO:1903064	biolink:NamedThing	positive regulation of reverse cholesterol transport	Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport.	got7fsn_ti	up regulation of reverse cholesterol transport|upregulation of reverse cholesterol transport|up-regulation of reverse cholesterol transport|activation of reverse cholesterol transport						rl	2014-05-28T15:15:40Z						biological_process											owl:Class	
GO:0062069	biolink:NamedThing	GARP complex binding	Binding to a GARP complex.	got7fsn_ti							dph	2018-08-31T14:11:17Z						molecular_function											owl:Class	
GO:0019040	biolink:NamedThing	obsolete viral host shutoff protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	viral host shutoff protein				This term was made obsolete because it does not represent a molecular function.	GO:0019057|GO:0004534				True				molecular_function											owl:Class	
GO:0001985	biolink:NamedThing	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure.	got7fsn_ti	down regulation of heart contraction rate in baroreceptor response to increased blood pressure|negative control of heart contraction rate in baroreceptor response to increased blood pressure|negative regulation of cardiac contraction rate in baroreceptor response to increased blood pressure|inhibition of heart contraction rate in baroreceptor response to increased blood pressure|down-regulation of heart contraction rate in baroreceptor response to increased blood pressure|negative regulation of heart contraction rate in baroreceptor response to increased blood pressure|downregulation of heart contraction rate in baroreceptor response to increased blood pressure													biological_process											owl:Class	
GO:0034311	biolink:NamedThing	diol metabolic process	The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic.	got7fsn_ti	diol metabolism|dihydric alcohol metabolic process													biological_process											owl:Class	
GO:0110022	biolink:NamedThing	regulation of cardiac muscle myoblast proliferation	Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.	got7fsn_ti							kmv	2017-06-29T15:11:47Z						biological_process											owl:Class	
GO:0043747	biolink:NamedThing	obsolete N2-acetyl-L-lysine deacetylase activity	OBSOLETE. Catalysis of the reaction: N2-acetyl-L-lysine + H2O = acetate + L-lysine.	got7fsn_ti	N-acetyl-lysine deacetylase activity	https://github.com/geneontology/go-ontology/issues/18908			This term was obsoleted because there is no evidence that it exists.					True		RHEA:28598|MetaCyc:RXN-5185		molecular_function											owl:Class	
GO:0048184	biolink:NamedThing	obsolete follistatin binding	OBSOLETE. Binding to the peptide hormone follistatin.	got7fsn_ti	follistatin binding			GO:0017046	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:0003396	biolink:NamedThing	cell adhesion involved in amphid sensory organ dendrite retrograde extension	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ.	got7fsn_ti							dph	2009-12-09T09:50:18Z						biological_process											owl:Class	
GO:2000122	biolink:NamedThing	negative regulation of stomatal complex development	Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development.	got7fsn_ti							dhl	2010-09-27T08:28:26Z						biological_process											owl:Class	
GO:1901499	biolink:NamedThing	response to hexane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus.	got7fsn_ti							tt	2012-10-16T15:14:49Z						biological_process											owl:Class	
GO:0072365	biolink:NamedThing	obsolete regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of cellular ketone metabolic process by negative regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by negative regulation of transcription from an RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:12:09Z		True				biological_process											owl:Class	
GO:0090002	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032326	biolink:NamedThing	Mo-molybdopterin cofactor catabolic process	The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.	got7fsn_ti	Mo-molybdopterin cofactor catabolism|Moco catabolism|Mo-molybdopterin cofactor breakdown|Mo-molybdopterin cofactor degradation|Moco catabolic process													biological_process											owl:Class	
GO:0032839	biolink:NamedThing	dendrite cytoplasm	All of the contents of a dendrite, excluding the surrounding plasma membrane.	got7fsn_ti	dendritic cytoplasm													cellular_component											owl:Class	
GO:0036207	biolink:NamedThing	obsolete positive regulation of histone gene expression	OBSOLETE. Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.	got7fsn_ti	upregulation of histone gene expression|up-regulation of histone gene expression|activation of histone gene expression|positive regulation of expression of histone-encoding gene				This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0045944	bf	2012-04-25T09:27:42Z		True				biological_process											owl:Class	
GO:1901168	biolink:NamedThing	3-chlorocatechol catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol.	got7fsn_ti	3-chlorocatechol catabolism|3-chlorocatechol breakdown|3-chlorocatechol degradation						yaf	2012-07-19T09:33:38Z						biological_process											owl:Class	
GO:0035827	biolink:NamedThing	obsolete rubidium ion transmembrane transporter activity	OBSOLETE. Enables the transfer of rubidium ions (Rb+) from one side of a membrane to the other.	got7fsn_ti	rubidium transmembrane transporter activity|Rb+ transmembrane transporter activity|rubidium cation transmembrane transporter activity				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-04T02:55:30Z		True				molecular_function											owl:Class	
GO:2000956	biolink:NamedThing	positive regulation of cyclodextrin metabolic process	Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process.	got7fsn_ti	positive regulation of cyclodextrin metabolism						tt	2011-08-01T02:22:09Z						biological_process											owl:Class	
GO:0010890	biolink:NamedThing	positive regulation of sequestering of triglyceride	Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.	got7fsn_ti	positive regulation of triglyceride sequestration|positive regulation of sequestering of triacylglycerol													biological_process											owl:Class	
GO:1903371	biolink:NamedThing	regulation of endoplasmic reticulum tubular network organization	Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization.	got7fsn_ti	regulation of ER tubular network organization|regulation of ER tubular network organisation|regulation of endoplasmic reticulum tubular network organisation						als	2014-08-22T11:01:14Z						biological_process											owl:Class	
GO:0070637	biolink:NamedThing	pyridine nucleoside metabolic process	The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.	got7fsn_ti	pyridine nucleoside metabolism						mah	2009-05-07T02:24:21Z						biological_process											owl:Class	
GO:1901024	biolink:NamedThing	4-hydroxyphenylacetate biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate.	got7fsn_ti	4-hydroxyphenylacetate synthesis|4-hydroxyphenylacetate formation|4-hydroxyphenylacetate anabolism|4-hydroxyphenylacetate biosynthesis						yaf	2012-06-18T02:32:06Z						biological_process											owl:Class	
GO:1903080	biolink:NamedThing	regulation of C-C chemokine receptor CCR7 signaling pathway	Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.	got7fsn_ti	regulation of C-C chemokine receptor CCR7 signalling pathway|regulation of CCR7 signaling pathway						rl	2014-05-29T18:32:49Z						biological_process											owl:Class	
GO:1901035	biolink:NamedThing	negative regulation of L-glutamine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell.	got7fsn_ti	down-regulation of L-glutamine uptake|inhibition of L-glutamine import|downregulation of L-glutamine uptake|inhibition of L-glutamine uptake|down regulation of L-glutamine uptake|down regulation of L-glutamine import|down-regulation of L-glutamine import|downregulation of L-glutamine import|negative regulation of L-glutamine uptake|negative regulation of L-glutamine import						al	2012-06-21T07:31:48Z						biological_process											owl:Class	
CHEBI:16148	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045951	biolink:NamedThing	positive regulation of mitotic recombination	Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis.	got7fsn_ti	stimulation of mitotic recombination|up-regulation of mitotic recombination|positive regulation of recombination within rDNA repeats|upregulation of mitotic recombination|up regulation of mitotic recombination|activation of mitotic recombination													biological_process											owl:Class	
GO:0075227	biolink:NamedThing	regulation of encysted zoospore germination	Any process that modulates the frequency, rate or extent of an encysted zoospore germination.	got7fsn_ti	modulation of encysted zoospore germination on or near host|regulation of encysted zoospore germination on or near host													biological_process											owl:Class	
GO:0006721	biolink:NamedThing	terpenoid metabolic process	The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.	got7fsn_ti	terpenoid metabolism													biological_process											owl:Class	
GO:0017020	biolink:NamedThing	myosin phosphatase regulator activity	Binds to and modulates of the activity of myosin phosphatase.	got7fsn_ti	myosin phosphatase, intrinsic regulator activity													molecular_function											owl:Class	
GO:0044035	biolink:NamedThing	obsolete multi-organism catabolic process	OBSOLETE. A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves more than one organism.	got7fsn_ti	multi-organismal catabolic process|multi-organism catabolism|multi-organismal catabolism	https://github.com/geneontology/go-ontology/issues/19769			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1903598	biolink:NamedThing	positive regulation of gap junction assembly	Any process that activates or increases the frequency, rate or extent of gap junction assembly.	got7fsn_ti	activation of gap junction assembly|up regulation of gap junction assembly|up-regulation of gap junction assembly|upregulation of gap junction assembly						rl	2014-11-07T18:51:53Z						biological_process											owl:Class	
GO:0046622	biolink:NamedThing	positive regulation of organ growth	Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0075346	biolink:NamedThing	obsolete modification by symbiont of host protein by ubiquitination	OBSOLETE. The process in which an organism adds one or more ubiquitin groups to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by symbiont of host protein by ubiquitylation|modification by symbiont of host protein by ubiquitinylation	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
CHEBI:64512	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010930	biolink:NamedThing	negative regulation of auxin mediated signaling pathway	Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.	got7fsn_ti	negative regulation of auxin mediated signalling pathway													biological_process											owl:Class	
GO:0035940	biolink:NamedThing	obsolete negative regulation of peptidase activity in other organism	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism.	got7fsn_ti	down-regulation of protease activity in other organism|down regulation of peptidase activity in other organism|downregulation of peptidase activity in other organism|inhibition of protease activity in other organism|negative regulation of protease activity in other organism	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.		bf	2011-07-22T02:59:40Z		True				biological_process											owl:Class	
GO:0010729	biolink:NamedThing	positive regulation of hydrogen peroxide biosynthetic process	Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	got7fsn_ti	positive regulation of hydrogen peroxide biosynthesis													biological_process											owl:Class	
GO:0035359	biolink:NamedThing	negative regulation of peroxisome proliferator activated receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	got7fsn_ti	negative regulation of PPAR signaling pathway|negative regulation of peroxisome proliferator-activated receptor signaling pathway|negative regulation of peroxisome proliferator activated receptor signalling pathway						bf	2010-03-05T10:41:35Z						biological_process											owl:Class	
GO:0046908	biolink:NamedThing	obsolete negative regulation of crystal formation	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the spontaneous (nonenzymatic) formation of crystals in a solution, for example, calcium oxalate crystals in urine.	got7fsn_ti	negative regulation of crystal formation|negative regulation of mineralization			GO:0050801	This term was made obsolete because a more appropriate term was created.					True				biological_process											owl:Class	
GO:0044031	biolink:NamedThing	obsolete modification by symbiont of host protein by phosphorylation	OBSOLETE. The process in which an organism adds a phosphate group to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0001186	biolink:NamedThing	obsolete RNA polymerase I transcription regulator recruiting activity	OBSOLETE. The function of binding to an RNA polymerase I (RNAP I) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.	got7fsn_ti	transcription factor activity, RNA polymerase I transcription factor recruiting|RNA polymerase I transcription factor recruiting transcription factor activity|RNA polymerase I transcription factor recruiting activity	https://github.com/geneontology/go-ontology/issues/18561		GO:0003712	The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'.		krc	2011-08-24T04:00:18Z		True				molecular_function											owl:Class	
CHEBI:48081	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015911	biolink:NamedThing	long-chain fatty acid import across plasma membrane	The directed movement of long-chain fatty acids from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	plasma membrane long-chain fatty acid transport													biological_process											owl:Class	
GO:0003926	biolink:NamedThing	obsolete ARF small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	ARF small monomeric GTPase activity			GO:0003924	This term was made obsolete because it represents a gene product.	GO:0016192|GO:0016191				True				molecular_function											owl:Class	
GO:0034305	biolink:NamedThing	regulation of asexual sporulation	Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.	got7fsn_ti	regulation of mitotic sporulation|regulation of mitotic spore formation|regulation of asexual spore formation													biological_process											owl:Class	
GO:0070668	biolink:NamedThing	positive regulation of mast cell proliferation	Any process that activates or increases the rate or extent of mast cell proliferation.	got7fsn_ti	up regulation of mast cell proliferation|upregulation of mast cell proliferation|up-regulation of mast cell proliferation|activation of mast cell proliferation|stimulation of mast cell proliferation						mah	2009-05-28T05:48:30Z						biological_process											owl:Class	
GO:0045560	biolink:NamedThing	obsolete regulation of TRAIL receptor biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.	got7fsn_ti	regulation of TRAIL receptor synthesis|regulation of TRAIL receptor anabolism|regulation of TRAIL receptor formation|regulation of TRAIL receptor biosynthesis	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0046097	biolink:NamedThing	deoxyuridine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.	got7fsn_ti	deoxyuridine synthesis|deoxyuridine biosynthesis|deoxyuridine anabolism|deoxyuridine formation													biological_process											owl:Class	
GO:1900492	biolink:NamedThing	negative regulation of [4Fe-4S] cluster assembly	Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly.	got7fsn_ti	down regulation of [4Fe-4S] cluster assembly|downregulation of 4Fe-4S cluster assembly|inhibition of 4Fe-4S cluster assembly|down-regulation of 4Fe-4S cluster assembly|down-regulation of [4Fe-4S] cluster biosynthetic process|negative regulation of 4Fe-4S cluster assembly|inhibition of [4Fe-4S] cluster assembly|down regulation of [4Fe-4S] cluster biosynthetic process|inhibition of [4Fe-4S] cluster biosynthetic process|downregulation of [4Fe-4S] cluster assembly|downregulation of [4Fe-4S] cluster biosynthetic process|down-regulation of [4Fe-4S] cluster assembly|down regulation of 4Fe-4S cluster assembly|negative regulation of [4Fe-4S] cluster biosynthetic process						tt	2012-05-02T03:49:00Z						biological_process											owl:Class	
GO:0019132	biolink:NamedThing	obsolete C-terminal processing peptidase activity	OBSOLETE. Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.	got7fsn_ti	protease Re|tail-specific protease activity|photosystem II D1 protein processing peptidase|C-terminal processing peptidase activity|Tsp protease|CtpA gene product (Synechocystis sp.)			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0006356	biolink:NamedThing	regulation of transcription by RNA polymerase I	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I.	got7fsn_ti	regulation of transcription from RNA polymerase I promoter|regulation of transcription from Pol I promoter													biological_process											owl:Class	
GO:0046040	biolink:NamedThing	IMP metabolic process	The chemical reactions and pathways involving IMP, inosine monophosphate.	got7fsn_ti	IMP metabolism													biological_process											owl:Class	
GO:1901531	biolink:NamedThing	hypochlorite binding	Binding to hypochlorite.	got7fsn_ti							pr	2012-10-24T07:15:22Z						molecular_function											owl:Class	
GO:0062170	biolink:NamedThing	lutein metabolic process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.	got7fsn_ti	lutein metabolism						dph	2019-11-18T15:56:36Z						biological_process											owl:Class	
GO:1904213	biolink:NamedThing	negative regulation of iodide transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport.	got7fsn_ti	downregulation of iodide transmembrane transport|down regulation of iodide transmembrane transport|inhibition of iodide transmembrane transport|down-regulation of iodide transmembrane transport						sl	2015-05-14T19:00:08Z						biological_process											owl:Class	
GO:1903789	biolink:NamedThing	regulation of amino acid transmembrane transport	Any process that modulates the frequency, rate or extent of amino acid transmembrane transport.	got7fsn_ti	regulation of amino acid membrane transport						al	2015-01-08T17:42:18Z						biological_process											owl:Class	
GO:0032772	biolink:NamedThing	negative regulation of tyrosinase activity	Any process that stops or reduces the activity of a tyrosinase enzyme.	got7fsn_ti	downregulation of monophenol oxygenase activity|negative regulation of monophenol oxygenase activity|inhibition of monophenol oxygenase activity|negative regulation of monophenol monooxygenase activity|down regulation of monophenol oxygenase activity|down-regulation of monophenol oxygenase activity	https://github.com/geneontology/go-ontology/issues/21024												biological_process											owl:Class	
GO:0120256	biolink:NamedThing	olefinic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).	got7fsn_ti	alkene substituted compound breakdown|alkene substituted compound catabolism|alkene substituted compound catabolic process|alkene substituted compound degradation	https://github.com/geneontology/go-ontology/issues/19936					krc	2020-09-02T23:30:41Z						biological_process											owl:Class	
GO:0140628	biolink:NamedThing	outward rectifier potassium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of an outwardly rectifying potassium channel.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21157					pg	2021-03-24T07:58:39Z						molecular_function											owl:Class	
GO:0062166	biolink:NamedThing	negative regulation of pseudohyphal septin ring assembly	Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly.	got7fsn_ti							dph	2019-11-07T15:57:39Z						biological_process											owl:Class	
PO:0025029	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005845	biolink:NamedThing	mRNA cap binding complex	Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.	got7fsn_ti	mRNA cap complex													cellular_component											owl:Class	
GO:0019403	biolink:NamedThing	galactitol biosynthetic process	The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	got7fsn_ti	galactitol synthesis|galactitol anabolism|galactitol formation|galactitol biosynthesis													biological_process											owl:Class	
GO:0099161	biolink:NamedThing	regulation of presynaptic dense core granule exocytosis	Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis.	got7fsn_ti	regulation of presynaptic dense core vesicle exocytosis						dos	2017-09-10T10:59:08Z						biological_process											owl:Class	
CHEBI:16670	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902344	biolink:NamedThing	negative regulation of maltose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport.	got7fsn_ti	downregulation of maltose transport|down-regulation of maltose transport|down regulation of maltose transport|inhibition of maltose transport						dph	2013-08-01T17:16:26Z						biological_process											owl:Class	
GO:0033865	biolink:NamedThing	nucleoside bisphosphate metabolic process	The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	nucleoside bisphosphate metabolism													biological_process											owl:Class	
GO:0034378	biolink:NamedThing	chylomicron assembly	The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron.	got7fsn_ti														biological_process											owl:Class	
GO:0035955	biolink:NamedThing	obsolete negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of dipeptide transport by inhibition of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by downregulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by negative regulation of transcription from Pol II promoter|negative regulation of dipeptide transport by down-regulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by down regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:2001050	biolink:NamedThing	negative regulation of tendon cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation.	got7fsn_ti	negative regulation of muscle attachment cell differentiation|negative regulation of tenocyte differentiation						yaf	2011-09-01T09:20:38Z						biological_process											owl:Class	
GO:1902574	biolink:NamedThing	obsolete negative regulation of leucine import by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of leucine import.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		al	2013-12-11T09:43:23Z		True				biological_process											owl:Class	
GO:0006989	biolink:NamedThing	obsolete unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase				This term was made obsolete because it represents a function rather than a process.	GO:0008452				True				biological_process											owl:Class	
GO:1901207	biolink:NamedThing	regulation of heart looping	Any process that modulates the frequency, rate or extent of heart looping.	got7fsn_ti	regulation of cardiac looping						rl	2012-07-31T07:15:47Z						biological_process											owl:Class	
GO:1902624	biolink:NamedThing	positive regulation of neutrophil migration	Any process that activates or increases the frequency, rate or extent of neutrophil migration.	got7fsn_ti	up-regulation of neutrophil migration|upregulation of neutrophil migration|activation of neutrophil migration|up regulation of neutrophil migration						sl	2014-01-15T18:58:58Z						biological_process											owl:Class	
GO:0140631	biolink:NamedThing	aldehyde dehydrogenase (NAD+) inhibitor activity	Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21265					pg	2021-04-09T09:40:21Z						molecular_function											owl:Class	
GO:2000835	biolink:NamedThing	negative regulation of androgen secretion	Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.	got7fsn_ti							bf	2011-07-26T08:39:48Z						biological_process											owl:Class	
GO:0035300	biolink:NamedThing	obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity	OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate, and ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate.	got7fsn_ti	inositol-1,3,4-trisphosphate 5/6-kinase activity|inositol 1,3,4-trisphosphate 6-kinase activity|inositol 1,3,4-trisphosphate 5-kinase activity|IP56K|ATP:1D-myo-inositol 1,3,4-trisphosphate 5-phosphotransferase activity|Ins(1,3,4)P3 5/6-kinase activity|inositol trisphosphate 5/6-kinase activity				This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052726|GO:0052725				True				molecular_function											owl:Class	
GO:0035555	biolink:NamedThing	obsolete initiation of Roundabout signal transduction	OBSOLETE. The process in which a SLIT protein causes activation of the receptor, Roundabout (ROBO).	got7fsn_ti	initiation of Roundabout signal transduction				This term was made obsolete because the meaning of the term is ambiguous.	GO:0038023|GO:0035385|GO:0048495	bf	2010-05-14T11:10:20Z		True				biological_process											owl:Class	
CL:0000188	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57966	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030601	biolink:NamedThing	obsolete aminopeptidase B activity	OBSOLETE. Catalysis of the release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys.	got7fsn_ti	cytosol aminopeptidase IV|aminopeptidase B activity|arylamidase II|L-arginine aminopeptidase activity|Cl--activated arginine aminopeptidase activity|arginyl aminopeptidase activity			GO:0004177	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1901460	biolink:NamedThing	regulation of response to formic acid	Any process that modulates the frequency, rate or extent of response to formic acid.	got7fsn_ti							tt	2012-10-02T14:27:54Z						biological_process											owl:Class	
PR:000001474	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046418	biolink:NamedThing	nopaline metabolic process	The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.	got7fsn_ti	nopaline metabolism													biological_process											owl:Class	
GO:0046054	biolink:NamedThing	dGMP metabolic process	The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).	got7fsn_ti	dGMP metabolism													biological_process											owl:Class	
GO:0046018	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.	got7fsn_ti	up-regulation of transcription from RNA polymerase I promoter during mitosis|activation of transcription from RNA polymerase I promoter during mitosis|positive regulation of transcription from RNA polymerase I promoter, mitotic|up regulation of transcription from RNA polymerase I promoter during mitosis|stimulation of transcription from RNA polymerase I promoter during mitosis|upregulation of transcription from RNA polymerase I promoter during mitosis|mitotic activation of transcription from Pol I promoter|positive regulation of transcription from Pol I promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0045943				True				biological_process											owl:Class	
GO:1903344	biolink:NamedThing	regulation of protein polyglycylation	Any process that modulates the frequency, rate or extent of protein polyglycylation.	got7fsn_ti							sart	2014-08-19T09:32:08Z						biological_process											owl:Class	
GO:0002606	biolink:NamedThing	positive regulation of dendritic cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.	got7fsn_ti	up regulation of dendritic cell antigen processing and presentation|stimulation of dendritic cell antigen processing and presentation|up-regulation of dendritic cell antigen processing and presentation|activation of dendritic cell antigen processing and presentation|upregulation of dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0100047	biolink:NamedThing	obsolete negative regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates inositol biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0043563	biolink:NamedThing	obsolete odorant transporter activity	OBSOLETE. Enables the directed movement of odorants, any substance capable of stimulating the sense of smell, into, out of or within a cell, or between cells.	got7fsn_ti										True				molecular_function											owl:Class	
GO:0030303	biolink:NamedThing	obsolete stromelysin 2 activity	OBSOLETE. Catalysis of the cleavage of peptide bonds in collagen with preferential cleavage where P1', P2' and P3' are hydrophobic residues; action on collagen types III, IV and V is weak.	got7fsn_ti	matrix metalloproteinase 10 activity|stromelysin 2 activity|proteoglycanase 2|transin 2 activity|MMP-10			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0003001	biolink:NamedThing	obsolete generation of a signal involved in cell-cell signaling	OBSOLETE. The cellular process that creates a physical entity or change in state, i.e. a signal, that originates in one cell and is used to transfer information to another cell. This process begins with the initial formation of the signal and ends with the mature form and placement of the signal.	got7fsn_ti	signal generation|generation of a signal involved in cell-cell signalling|generation of a signal involved in cell-cell signaling|formation of a signal				This term was made obsolete because biosynthesis of a signal occurs before the start of cell-cell signaling.	GO:0023061|GO:0031130|GO:0010496|GO:0007267				True				biological_process											owl:Class	
GO:0106020	biolink:NamedThing	regulation of vesicle docking	Any process that modulates the frequency, rate or extent of vesicle docking.	got7fsn_ti	regulation of vesicle to membrane docking						hjd	2017-05-16T13:58:54Z						biological_process											owl:Class	
GO:2001307	biolink:NamedThing	xanthone-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a xanthone-containing compound.	got7fsn_ti	xanthones biosynthetic process|xanthones synthesis|xanthone-containing compound formation|xanthones biosynthesis|xanthone-containing compound biosynthesis|xanthones formation|xanthone-containing compound synthesis|xanthone biosynthetic process|xanthone-containing compound anabolism|xanthone biosynthesis|xanthones anabolism						bf	2012-03-14T10:35:44Z						biological_process											owl:Class	
GO:0046603	biolink:NamedThing	negative regulation of mitotic centrosome separation	Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation.	got7fsn_ti	down-regulation of mitotic centrosome separation|down regulation of mitotic centrosome separation|downregulation of mitotic centrosome separation|inhibition of mitotic centrosome separation													biological_process											owl:Class	
GO:2000837	biolink:NamedThing	regulation of androstenedione secretion	Any process that modulates the frequency, rate or extent of androstenedione secretion.	got7fsn_ti	regulation of androst-4-ene-3,17-dione secretion						bf	2011-07-26T08:40:36Z						biological_process											owl:Class	
GO:0086077	biolink:NamedThing	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	got7fsn_ti	gap junction channel activity involved in atrioventricular node cell-bundle of His cell electrical coupling						dph	2011-11-22T10:29:53Z						molecular_function											owl:Class	
GO:1901906	biolink:NamedThing	diadenosine pentaphosphate metabolic process	The chemical reactions and pathways involving diadenosine pentaphosphate.	got7fsn_ti	diadenosyl pentaphosphate metabolism|diadenosyl pentaphosphate metabolic process|diadenosine pentaphosphate metabolism						al	2013-02-13T13:48:16Z						biological_process											owl:Class	
GO:2000619	biolink:NamedThing	negative regulation of histone H4-K16 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H4-K16 acetylation.	got7fsn_ti	negative regulation of histone H4 acetylation at K16						vk	2011-04-18T03:19:27Z						biological_process											owl:Class	
GO:0075117	biolink:NamedThing	obsolete suppression by symbiont of host transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition by symbiont of host transmembrane receptor-mediated cAMP signal transduction|downregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|negative regulation by symbiont of host transmembrane receptor-mediated cAMP signaling				The reason for obsoletion is that there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0070799	biolink:NamedThing	regulation of conidiophore stalk development	Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.	got7fsn_ti							mah	2009-07-08T04:03:40Z						biological_process											owl:Class	
GO:0031495	biolink:NamedThing	negative regulation of mating type switching	Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.	got7fsn_ti	down-regulation of mating type switching|down regulation of mating type switching|inhibition of mating type switching|downregulation of mating type switching													biological_process											owl:Class	
GO:1905590	biolink:NamedThing	fibronectin fibril organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril.	got7fsn_ti							dph	2016-10-25T12:04:50Z						biological_process											owl:Class	
GO:0036060	biolink:NamedThing	slit diaphragm assembly	The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.	got7fsn_ti							bf	2011-12-12T04:38:40Z						biological_process											owl:Class	
GO:0032082	biolink:NamedThing	negative regulation of type III site-specific deoxyribonuclease activity	Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity.	got7fsn_ti	down regulation of type III restriction endodeoxyribonuclease activity|negative regulation of type III restriction endodeoxyribonuclease activity|type III restriction enzyme inhibitor|type III restriction endodeoxyribonuclease inhibitor|down-regulation of type III restriction endodeoxyribonuclease activity|inhibition of type III restriction endodeoxyribonuclease activity|downregulation of type III restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0106108	biolink:NamedThing	negative regulation of (R)-mevalonic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.	got7fsn_ti							hjd	2018-03-27T14:15:55Z						biological_process											owl:Class	
FAO:0000041	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903368	biolink:NamedThing	regulation of foraging behavior	Any process that modulates the frequency, rate or extent of foraging behavior.	got7fsn_ti							mr	2014-08-22T03:03:04Z						biological_process											owl:Class	
CHEBI:17847	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140406	biolink:NamedThing	L-alanine export across the plasma membrane	The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti							pg	2019-12-11T14:13:07Z						biological_process											owl:Class	
CHEBI:15685	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015259	biolink:NamedThing	obsolete glutamate channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	glutamate channel activity				This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True				molecular_function											owl:Class	
GO:0100023	biolink:NamedThing	obsolete regulation of meiotic nuclear division by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0062133	biolink:NamedThing	negative regulation of L-glutamine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis.	got7fsn_ti							dph	2019-06-27T13:47:21Z						biological_process											owl:Class	
GO:1902439	biolink:NamedThing	cellular response to vanadate(3-)	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.	got7fsn_ti							di	2013-10-10T10:50:30Z						biological_process											owl:Class	
GO:2000206	biolink:NamedThing	regulation of ribosomal small subunit export from nucleus	Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus.	got7fsn_ti	regulation of ribosomal small subunit export from cell nucleus|regulation of ribosomal small subunit transport from nucleus to cytoplasm|regulation of 30S ribosomal subunit export from nucleus|regulation of ribosomal small subunit-nucleus export|regulation of ribosomal small subunit export out of nucleus|regulation of 40S ribosomal subunit export from nucleus						mah	2010-10-26T10:54:09Z						biological_process											owl:Class	
GO:1905011	biolink:NamedThing	transmembrane phosphate ion transport from cytosol to vacuole	The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen.	got7fsn_ti	vacuolar phosphate transport						tb	2016-03-03T00:34:12Z			GO:0007037			biological_process											owl:Class	
GO:0031277	biolink:NamedThing	obsolete positive regulation of lateral pseudopodium assembly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.	got7fsn_ti	stimulation of lateral pseudopodium formation|upregulation of lateral pseudopodium formation|up regulation of lateral pseudopodium formation|positive regulation of lateral pseudopodium formation|up-regulation of lateral pseudopodium formation|activation of lateral pseudopodium formation	https://github.com/geneontology/go-ontology/issues/21738			The regulation of lateral pseudopodium assembly terms were not used consistently. The negative regulation term has been replaced by GO:0120320 lateral pseudopodium retraction.					True				biological_process											owl:Class	
GO:1904082	biolink:NamedThing	pyrimidine nucleobase transmembrane transport	The process in which pyrimidine is transported across a membrane.	got7fsn_ti							tb	2015-03-25T00:13:16Z						biological_process											owl:Class	
GO:0072307	biolink:NamedThing	regulation of metanephric nephron tubule epithelial cell differentiation	Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.	got7fsn_ti							mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:0043923	biolink:NamedThing	positive regulation by host of viral transcription	Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.	got7fsn_ti	positive regulation of viral transcription by host													biological_process											owl:Class	
GO:0044669	biolink:NamedThing	sodium:galactoside symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in).	got7fsn_ti							jl	2012-08-08T12:55:32Z						molecular_function											owl:Class	
GO:0015970	biolink:NamedThing	guanosine tetraphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.	got7fsn_ti	guanosine tetraphosphate anabolism|guanosine tetraphosphate (5'-ppGpp-3') biosynthesis|guanosine tetraphosphate formation|guanosine tetraphosphate (5'-ppGpp-3') biosynthetic process|guanosine tetraphosphate synthesis|guanosine tetraphosphate biosynthesis													biological_process											owl:Class	
GO:0010755	biolink:NamedThing	regulation of plasminogen activation	Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.	got7fsn_ti														biological_process											owl:Class	
GO:0015339	biolink:NamedThing	obsolete cobalt, zinc uptake permease activity	OBSOLETE. Catalysis of the reaction: (Zn2+ or Co2+)(out) = (Zn2+ or Co2+)(in). The activity is driven by proton motive force, possibly by proton symport.	got7fsn_ti	cobalt, zinc uptake permease activity				This term was made obsolete because it represents more than one molecular function.	GO:0015087|GO:0005385				True				molecular_function											owl:Class	
GO:0005182	biolink:NamedThing	obsolete lipopeptide hormone	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lipopeptide hormone				This term was made obsolete because it describes a type of hormone rather than a molecular function.	GO:0005179				True				molecular_function											owl:Class	
GO:1905217	biolink:NamedThing	response to astaxanthin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.	got7fsn_ti	response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione						sl	2016-06-06T21:30:00Z						biological_process											owl:Class	
GO:1905303	biolink:NamedThing	positive regulation of macropinocytosis	Any process that activates or increases the frequency, rate or extent of macropinocytosis.	got7fsn_ti	activation of macropinocytosis|up-regulation of macropinocytosis|upregulation of macropinocytosis|up regulation of macropinocytosis						pad	2016-07-04T14:16:49Z						biological_process											owl:Class	
CHEBI:27991	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006462	biolink:NamedThing	obsolete protein complex assembly, multichaperone pathway	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	protein complex assembly, multichaperone pathway				This term was made obsolete because the string was ambiguous and the original meaning of the term was hence unknown.	GO:0006457|GO:0051131				True				biological_process											owl:Class	
GO:2001217	biolink:NamedThing	obsolete regulation of S/G2 transition of mitotic cell cycle	OBSOLETE. Any process that modulates the frequency, rate or extent of S/G2 transition of mitotic cell cycle.	got7fsn_ti	regulation of S/G2 transition of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.	GO:0044770	dph	2011-11-16T09:14:42Z		True				biological_process											owl:Class	
GO:0045984	biolink:NamedThing	negative regulation of pyrimidine nucleobase metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.	got7fsn_ti	down-regulation of pyrimidine base metabolic process|negative regulation of pyrimidine base metabolic process|inhibition of pyrimidine base metabolic process|negative regulation of pyrimidine base metabolism|down regulation of pyrimidine base metabolic process|downregulation of pyrimidine base metabolic process													biological_process											owl:Class	
CHEBI:26432	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904689	biolink:NamedThing	negative regulation of cytoplasmic translational initiation	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.	got7fsn_ti	down-regulation of cytoplasmic translational initiation|downregulation of cytoplasmic translational initiation|down regulation of cytoplasmic translational initiation|inhibition of cytoplasmic translational initiation						dos	2015-09-25T14:39:44Z						biological_process											owl:Class	
GO:0040014	biolink:NamedThing	regulation of multicellular organism growth	Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.	got7fsn_ti	regulation of body size|regulation of body growth													biological_process											owl:Class	
GO:1905440	biolink:NamedThing	cellular response to chondroitin 6'-sulfate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.	got7fsn_ti							cvs	2016-09-14T18:56:19Z						biological_process											owl:Class	
GO:0061111	biolink:NamedThing	epithelial-mesenchymal cell signaling involved in lung development	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.	got7fsn_ti	epithelial-mesenchymal cell signalling involved in lung development						dph	2010-05-05T11:14:38Z						biological_process											owl:Class	
GO:1900553	biolink:NamedThing	asperfuranone catabolic process	The chemical reactions and pathways resulting in the breakdown of asperfuranone.	got7fsn_ti	asperfuranone breakdown|asperfuranone catabolism|asperfuranone degradation						di	2012-05-15T01:31:35Z						biological_process											owl:Class	
GO:0010186	biolink:NamedThing	positive regulation of cellular defense response	Any process that activates or increases the frequency, rate or extent of cellular defense response.	got7fsn_ti	upregulation of cellular defense response|stimulation of cellular defense response|positive regulation of cellular defence response|up regulation of cellular defense response|activation of cellular defense response|up-regulation of cellular defense response													biological_process											owl:Class	
GO:1901456	biolink:NamedThing	positive regulation of response to toluene	Any process that activates or increases the frequency, rate or extent of response to toluene.	got7fsn_ti	up regulation of response to toluene|activation of response to toluene|up-regulation of response to toluene|upregulation of response to toluene						tt	2012-10-02T14:23:45Z						biological_process											owl:Class	
GO:2000132	biolink:NamedThing	negative regulation of tyramine signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway.	got7fsn_ti	negative regulation of tyramine signalling pathway						mah	2010-09-29T09:32:00Z						biological_process											owl:Class	
GO:1902847	biolink:NamedThing	regulation of neuronal signal transduction	Any process that modulates the frequency, rate or extent of neuronal signal transduction.	got7fsn_ti							sjp	2014-04-02T10:11:12Z						biological_process											owl:Class	
GO:0090226	biolink:NamedThing	regulation of microtubule nucleation by Ran protein signal transduction	Any series of molecular signals in which a Ran GTPase relays one or more of the signals resulting in the modulation of the rate, frequency or extent of microtubule nucleation.	got7fsn_ti							tb	2010-01-13T11:35:31Z						biological_process											owl:Class	
GO:1903257	biolink:NamedThing	selenoneine biosynthetic process	The chemical reactions and pathways resulting in the formation of selenoneine.	got7fsn_ti	selenoneine anabolism|selenoneine biosynthesis|selenoneine synthesis|selenoneine formation|L-selenoneine biosynthetic process						mah	2014-08-06T09:14:33Z						biological_process											owl:Class	
GO:0046431	biolink:NamedThing	(R)-4-hydroxymandelate metabolic process	The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate).	got7fsn_ti	(R)-4-hydroxymandelate metabolism													biological_process											owl:Class	
GO:0052232	biolink:NamedThing	obsolete positive aerotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive aerotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0044397	biolink:NamedThing	obsolete actin cortical patch internalization	OBSOLETE. A process of actin cortical patch localization in which the patch moves from the cell surface to the inside of the cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20490		GO:0006897	The reason for obsoletion is that it represents a phenotype.		jl	2011-12-21T03:37:11Z		True				biological_process											owl:Class	
GO:0018923	biolink:NamedThing	limonene metabolic process	The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.	got7fsn_ti	limonene metabolism											UM-BBD_pathwayID:lim		biological_process											owl:Class	
GO:1900655	biolink:NamedThing	regulation of diorcinol biosynthetic process	Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process.	got7fsn_ti	regulation of diorcinol synthesis|regulation of diorcinol anabolism|regulation of diorcinol biosynthesis|regulation of diorcinol formation						di	2012-05-22T04:08:40Z						biological_process											owl:Class	
GO:1900856	biolink:NamedThing	negative regulation of fumitremorgin B biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of fumitremorgin B biosynthetic process.	got7fsn_ti	down-regulation of fumitremorgin B biosynthetic process|downregulation of fumitremorgin B biosynthetic process|down regulation of fumitremorgin B biosynthetic process						di	2012-06-07T09:51:01Z						biological_process											owl:Class	
GO:1900559	biolink:NamedThing	austinol catabolic process	The chemical reactions and pathways resulting in the breakdown of austinol.	got7fsn_ti	austinol catabolism|austinol breakdown|austinol degradation						di	2012-05-15T06:27:22Z						biological_process											owl:Class	
GO:2000413	biolink:NamedThing	regulation of fibronectin-dependent thymocyte migration	Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration.	got7fsn_ti	regulation of fibronectin-dependent immature T cell migration|regulation of fibronectin-dependent thymic lymphocyte migration|regulation of fibronectin-dependent immature T-lymphocyte migration|regulation of fibronectin-dependent immature T lymphocyte migration|regulation of fibronectin-dependent immature T-cell migration						mah	2011-02-23T01:38:08Z						biological_process											owl:Class	
GO:1990036	biolink:NamedThing	calcium ion import into sarcoplasmic reticulum	The directed movement of calcium ions into a sarcoplasmic reticulum.	got7fsn_ti							tb	2013-02-07T23:22:27Z						biological_process											owl:Class	
GO:0042991	biolink:NamedThing	obsolete transcription factor import into nucleus	OBSOLETE. The directed movement of a transcription factor from the cytoplasm to the nucleus.	got7fsn_ti	transcription factor import into cell nucleus|transcription factor transport from cytoplasm to nucleus|transcription factor-nucleus import				The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0006606				True				biological_process											owl:Class	
GO:1902342	biolink:NamedThing	xylitol export	The directed movement of xylitol out of a cell or organelle.	got7fsn_ti							se	2013-07-30T16:09:55Z						biological_process											owl:Class	
GO:0030188	biolink:NamedThing	obsolete chaperone regulator activity	OBSOLETE. Modulates the activity of a molecular chaperone.	got7fsn_ti	chaperone regulator activity				This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'.	GO:0051082|GO:0051787|GO:0006457				True				molecular_function											owl:Class	
GO:0034063	biolink:NamedThing	stress granule assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.	got7fsn_ti	SG assembly													biological_process											owl:Class	
GO:1903894	biolink:NamedThing	regulation of IRE1-mediated unfolded protein response	Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.	got7fsn_ti	regulation of IRE1 signal transduction pathway|regulation of IRE1p unfolded protein response|regulation of IRE1alpha unfolded protein response|regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|regulation of IRE1 branch of UPR|regulation of ERN1-mediated unfolded protein response|regulation of IRE1 signaling in response to endoplasmic reticulum stress|regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|regulation of UPR signaling by IRE1 stress sensor						bf	2015-02-09T10:17:46Z						biological_process											owl:Class	
GO:0110065	biolink:NamedThing	regulation of interphase mitotic telomere clustering	Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.	got7fsn_ti	regulation of mitotic telomere clustering during interphase						kmv	2017-11-17T22:03:40Z						biological_process											owl:Class	
GO:0010810	biolink:NamedThing	regulation of cell-substrate adhesion	Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.	got7fsn_ti														biological_process											owl:Class	
GO:1900862	biolink:NamedThing	negative regulation of cordyol C biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process.	got7fsn_ti	down-regulation of cordyol C biosynthetic process|down regulation of cordyol C biosynthetic process|downregulation of cordyol C biosynthetic process						di	2012-06-07T01:56:38Z						biological_process											owl:Class	
GO:0006135	biolink:NamedThing	obsolete dihydropteridine reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dihydropteridine reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051067|GO:0004155|GO:0022900				True				biological_process											owl:Class	
GO:1900024	biolink:NamedThing	regulation of substrate adhesion-dependent cell spreading	Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading.	got7fsn_ti	regulation of cell spreading during cell substrate adhesion|regulation of substrate adhesion dependent cell spreading						yaf	2012-01-12T05:00:39Z						biological_process											owl:Class	
GO:0001029	biolink:NamedThing	obsolete RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	got7fsn_ti	RNA polymerase III type 3 promoter polymerase recruiting transcription factor activity						krc	2010-08-23T12:52:40Z		True				molecular_function											owl:Class	
GO:2000936	biolink:NamedThing	regulation of cellotriose catabolic process	Any process that modulates the frequency, rate or extent of cellotriose catabolic process.	got7fsn_ti	regulation of cellotriose catabolism						tt	2011-08-01T12:45:26Z						biological_process											owl:Class	
GO:1901469	biolink:NamedThing	regulation of syringal lignin catabolic process	Any process that modulates the frequency, rate or extent of syringal lignin catabolic process.	got7fsn_ti	regulation of S-lignin catabolic process|regulation of syringal lignin breakdown|regulation of syringal lignin catabolism|regulation of syringal lignin degradation						tt	2012-10-02T14:41:12Z						biological_process											owl:Class	
GO:2001237	biolink:NamedThing	negative regulation of extrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.	got7fsn_ti	negative regulation of extrinsic apoptosis|negative regulation of extrinsic apoptotic signalling pathway						pr	2011-11-24T01:30:11Z						biological_process											owl:Class	
GO:0019545	biolink:NamedThing	arginine catabolic process to succinate	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.	got7fsn_ti	arginine breakdown to succinate|arginine degradation to succinate											MetaCyc:ARGDEG-V-PWY|MetaCyc:ARGDEG-III-PWY|MetaCyc:AST-PWY|MetaCyc:ARGDEG-IV-PWY		biological_process											owl:Class	
GO:0070190	biolink:NamedThing	obsolete inositol hexakisphosphate 1-kinase or 3-kinase activity	OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.	got7fsn_ti	inositol hexakisphosphate 1-kinase or 3-kinase activity				This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052724|GO:0052723				True				molecular_function											owl:Class	
GO:1901011	biolink:NamedThing	(S)-reticuline catabolic process	The chemical reactions and pathways resulting in the breakdown of (S)-reticuline.	got7fsn_ti	(S)-reticuline breakdown|(S)-reticuline catabolism|(S)-reticuline degradation						yaf	2012-06-15T10:46:45Z						biological_process											owl:Class	
GO:0043329	biolink:NamedThing	obsolete protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	OBSOLETE. The process of directing proteins towards a membrane using signals contained within the protein, occurring that contributes to ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway.	got7fsn_ti	protein targeting to membrane during ubiquitin-dependent protein breakdown via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein degradation via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein degradation via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein catabolic process via the MVB pathway|protein membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein breakdown via the MVB pathway				The reason for obsoleting is that the term is not cleary defined, ie the membrane to which proteins are being targeted is not specified.					True				biological_process											owl:Class	
GO:0045681	biolink:NamedThing	positive regulation of R8 cell differentiation	Any process that activates or increases the frequency, rate or extent of R8 cell differentiation.	got7fsn_ti	up regulation of R8 differentiation|activation of R8 differentiation|positive regulation of R8 differentiation|up-regulation of R8 differentiation|stimulation of R8 differentiation|upregulation of R8 differentiation													biological_process											owl:Class	
GO:0006965	biolink:NamedThing	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.	got7fsn_ti	stimulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|activation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|anti-Gram-positive bacterial polypeptide induction|up regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|up-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|upregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|anti-Gram-positive bacterial peptide induction													biological_process											owl:Class	
GO:0009666	biolink:NamedThing	plastid outer membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid.	got7fsn_ti	plastid outer membrane organisation|plastid outer membrane organization and biogenesis													biological_process											owl:Class	
GO:0140048	biolink:NamedThing	manganese ion export across plasma membrane	The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	manganese ion export from cell						pg	2017-06-23T14:25:00Z						biological_process											owl:Class	
GO:1904521	biolink:NamedThing	negative regulation of myofibroblast cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process.	got7fsn_ti	down regulation of MFB apoptotic process|down regulation of myofibroblast cell apoptotic process|down regulation of myofibroblast cell apoptosis|negative regulation of MFB apoptosis|negative regulation of MFB apoptotic process|downregulation of myofibroblast cell apoptotic process|inhibition of MFB apoptotic process|downregulation of MFB apoptotic process|inhibition of myofibroblast cell apoptotic process|negative regulation of myofibroblast cell apoptosis|inhibition of myofibroblast cell apoptosis|down-regulation of myofibroblast cell apoptotic process|downregulation of myofibroblast cell apoptosis|down-regulation of MFB apoptosis|downregulation of MFB apoptosis|down-regulation of MFB apoptotic process|down-regulation of myofibroblast cell apoptosis|inhibition of MFB apoptosis|down regulation of MFB apoptosis						sl	2015-07-29T15:52:20Z						biological_process											owl:Class	
GO:0070472	biolink:NamedThing	regulation of uterine smooth muscle contraction	Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.	got7fsn_ti	regulation of myometrium contraction|regulation of myometrial smooth muscle contraction|regulation of myometrial contraction													biological_process											owl:Class	
GO:0009118	biolink:NamedThing	regulation of nucleoside metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.	got7fsn_ti	regulation of nucleoside metabolism													biological_process											owl:Class	
GO:0090011	biolink:NamedThing	Wnt signaling pathway involved in primitive streak formation	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes that contribute to the formation of the primitive streak.	got7fsn_ti	Wnt-activated signaling pathway involved in primitive streak formation|Wnt receptor signaling pathway involved in primitive streak formation|Wnt receptor signalling pathway involved in primitive streak formation						tb	2009-07-29T10:44:53Z						biological_process											owl:Class	
GO:1900055	biolink:NamedThing	regulation of leaf senescence	Any process that modulates the frequency, rate or extent of leaf senescence.	got7fsn_ti							tb	2012-01-24T11:51:24Z						biological_process											owl:Class	
GO:0061716	biolink:NamedThing	miRNA export from nucleus	The directed movement of a processed miRNA from the nucleus to the cytoplasm.	got7fsn_ti							dph	2015-06-29T08:54:41Z						biological_process											owl:Class	
GO:0008268	biolink:NamedThing	obsolete receptor signaling protein tyrosine kinase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	receptor signalling protein tyrosine kinase signalling protein activity|receptor signaling protein tyrosine kinase signaling protein activity				This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556				True				molecular_function											owl:Class	
GO:0072749	biolink:NamedThing	cellular response to cytochalasin B	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.	got7fsn_ti							mah	2012-08-31T12:37:15Z						biological_process											owl:Class	
CHEBI:27551	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052425	biolink:NamedThing	obsolete modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system	OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type II secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0062224	biolink:NamedThing	positive regulation of somatic muscle development	Any process that increases the rate, frequency or extent of somatic muscle development.	got7fsn_ti							dph	2020-03-13T19:03:38Z						biological_process											owl:Class	
GO:0045654	biolink:NamedThing	positive regulation of megakaryocyte differentiation	Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.	got7fsn_ti	up regulation of megakaryocyte differentiation|up-regulation of megakaryocyte differentiation|activation of megakaryocyte differentiation|stimulation of megakaryocyte differentiation|upregulation of megakaryocyte differentiation													biological_process											owl:Class	
GO:0150168	biolink:NamedThing	negative regulation of histone H3-K4 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 acetylation.	got7fsn_ti							bc	2020-01-14T12:34:01Z						biological_process											owl:Class	
GO:1990591	biolink:NamedThing	asparagine transmembrane import into vacuole	The directed movement of asparagine into the vacuole across the vacuolar membrane.	got7fsn_ti							vw	2014-12-15T16:33:46Z						biological_process											owl:Class	
GO:0090518	biolink:NamedThing	L-arginine transmembrane import into vacuole	The directed movement of L-arginine into the vacuole across the vacuolar membrane.	got7fsn_ti	vacuolar arginine import|arginine transmembrane import into vacuole						tb	2012-09-24T14:12:46Z			GO:0090458			biological_process											owl:Class	
GO:0010529	biolink:NamedThing	negative regulation of transposition	Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.	got7fsn_ti														biological_process											owl:Class	
GO:2000419	biolink:NamedThing	regulation of eosinophil extravasation	Any process that modulates the frequency, rate or extent of eosinophil extravasation.	got7fsn_ti							mah	2011-02-23T01:46:47Z						biological_process											owl:Class	
GO:1904287	biolink:NamedThing	positive regulation of protein-pyridoxal-5-phosphate linkage	Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.	got7fsn_ti	upregulation of protein-pyridoxal-5-phosphate linkage|stimulation of protein-pyridoxal-5-phosphate linkage|up-regulation of protein-pyridoxal-5-phosphate linkage|activation of protein-pyridoxal-5-phosphate linkage|up regulation of protein-pyridoxal-5-phosphate linkage						mcc	2015-06-05T17:21:28Z						biological_process											owl:Class	
GO:0006922	biolink:NamedThing	obsolete cleavage of lamin involved in execution phase of apoptosis	OBSOLETE. The proteolytic degradation of lamins during apoptosis, leading to the irreversible breakdown of the nuclear lamina.	got7fsn_ti	cleavage of lamin|cleavage of lamin involved in execution phase of apoptosis				This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'.	GO:0097200				True				biological_process											owl:Class	
GO:0015857	biolink:NamedThing	uracil transport	The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0008530	biolink:NamedThing	obsolete exogenous peptide receptor activity	OBSOLETE. Combining with an extracellular peptide to initiate a change in cell activity.	got7fsn_ti	exogenous peptide receptor activity				This term was made obsolete because it contains both component and function information.	GO:0001653|GO:0005576				True				molecular_function											owl:Class	
GO:1905159	biolink:NamedThing	obsolete negative regulation of Factor XII activation	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of Factor XII activation.	got7fsn_ti	negative regulation of Hageman factor activation|downregulation of Hageman factor activation|downregulation of Factor XII activation|down-regulation of Factor XII activation|inhibition of Hageman factor activation|inhibition of Factor XII activation|down regulation of Factor XII activation|down regulation of Hageman factor activation|down-regulation of Hageman factor activation				This term was accidentally approved after TermGenie review.  It should not have been approved.		sl	2016-04-19T23:03:34Z		True				biological_process											owl:Class	
GO:0046986	biolink:NamedThing	negative regulation of hemoglobin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	got7fsn_ti	negative regulation of hemoglobin formation|inhibition of hemoglobin biosynthetic process|negative regulation of haemoglobin biosynthesis|negative regulation of hemoglobin synthesis|negative regulation of hemoglobin biosynthesis|down regulation of hemoglobin biosynthetic process|negative regulation of hemoglobin anabolism|downregulation of hemoglobin biosynthetic process|down-regulation of hemoglobin biosynthetic process|negative regulation of haemoglobin biosynthetic process													biological_process											owl:Class	
GO:0075287	biolink:NamedThing	positive regulation of sporangiospore formation	Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.	got7fsn_ti														biological_process											owl:Class	
GO:1902735	biolink:NamedThing	negative regulation of receptor-mediated virion attachment to host cell	Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell.	got7fsn_ti	down regulation of receptor-mediated virion attachment to host cell|down-regulation of virion attachment, binding of host cell surface receptor|negative regulation of virion attachment, binding of host cell surface receptor|down regulation of virion attachment, binding of host cell surface receptor|inhibition of receptor-mediated virion attachment to host cell|downregulation of virion attachment, binding of host cell surface receptor|down-regulation of receptor-mediated virion attachment to host cell|downregulation of receptor-mediated virion attachment to host cell|inhibition of virion attachment, binding of host cell surface receptor						als	2014-02-25T12:26:06Z						biological_process											owl:Class	
GO:1902460	biolink:NamedThing	regulation of mesenchymal stem cell proliferation	Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation.	got7fsn_ti	regulation of MSC proliferation						pm	2013-10-22T10:01:00Z						biological_process											owl:Class	
GO:0120163	biolink:NamedThing	negative regulation of cold-induced thermogenesis	Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.	got7fsn_ti	negative regulation of CIT						krc	2018-05-14T17:18:59Z						biological_process											owl:Class	
GO:1900316	biolink:NamedThing	negative regulation of maltopentaose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport.	got7fsn_ti	down-regulation of maltopentaose transport|downregulation of maltopentaose transport|down regulation of maltopentaose transport|inhibition of maltopentaose transport						tt	2012-04-05T07:59:56Z						biological_process											owl:Class	
GO:0060760	biolink:NamedThing	positive regulation of response to cytokine stimulus	Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.	got7fsn_ti							dph	2009-06-22T02:58:04Z						biological_process											owl:Class	
GO:0070496	biolink:NamedThing	positive regulation of thrombin-activated receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.	got7fsn_ti	positive regulation of thrombin receptor signaling pathway|positive regulation of thrombin receptor signalling pathway													biological_process											owl:Class	
GO:1902919	biolink:NamedThing	poly(5-hydroxyvalerate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate).	got7fsn_ti	poly(5-hydroxyvalerate) synthesis|poly(5-hydroxyvalerate) formation|poly(5-hydroxyvalerate) biosynthesis|poly(5-hydroxyvalerate) anabolism						tt	2014-04-21T18:47:12Z						biological_process											owl:Class	
GO:0009929	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901687	biolink:NamedThing	glutathione derivative biosynthetic process	The chemical reactions and pathways resulting in the formation of glutathione derivative.	got7fsn_ti	glutathione derivative synthesis|glutathione derivative formation|glutathione derivative biosynthesis|glutathione derivative anabolism						pr	2012-12-05T11:57:20Z						biological_process											owl:Class	
GO:0015570	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046363	biolink:NamedThing	ribitol catabolic process	The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.	got7fsn_ti	ribitol catabolism|ribitol degradation|ribitol breakdown													biological_process											owl:Class	
GO:1903149	biolink:NamedThing	obsolete adenine transmembrane transporter activity involved in adenine import into cell	OBSOLETE. Any adenine transmembrane transporter activity that is involved in adenine import into cell.	got7fsn_ti	adenine transmembrane transporter activity involved in adenine import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:30Z		True				molecular_function											owl:Class	
GO:1905758	biolink:NamedThing	positive regulation of primary cell septum biogenesis	Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis.	got7fsn_ti							vw	2016-12-12T18:10:07Z						biological_process											owl:Class	
GO:1904649	biolink:NamedThing	regulation of fat cell apoptotic process	Any process that modulates the frequency, rate or extent of fat cell apoptotic process.	got7fsn_ti	regulation of fat cell apoptosis|regulation of adipocyte apoptosis|regulation of adipose cell apoptotic process|regulation of adipose cell apoptosis|regulation of adipocyte apoptotic process						sl	2015-08-31T20:59:28Z						biological_process											owl:Class	
GO:0150044	biolink:NamedThing	regulation of postsynaptic dense core vesicle exocytosis	Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis.	got7fsn_ti							bc	2018-04-20T13:34:32Z						biological_process											owl:Class	
GO:2000173	biolink:NamedThing	negative regulation of branching morphogenesis of a nerve	Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve.	got7fsn_ti							rl	2010-10-07T12:07:56Z						biological_process											owl:Class	
GO:0120313	biolink:NamedThing	regulation of oocyte karyosome formation	Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21298					krc	2021-04-19T21:34:15Z						biological_process											owl:Class	
GO:0008141	biolink:NamedThing	obsolete puparial glue (sensu Diptera)	OBSOLETE. A glue which attaches the pupae to the substrate during metamorphosis, as in, but not restricted to, the true flies (Diptera, ncbi_taxonomy_id:7147).	got7fsn_ti	puparial glue (sensu Diptera)				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005198|GO:0007594				True				molecular_function											owl:Class	
GO:0140141	biolink:NamedThing	mitochondrial potassium ion transmembrane transport	The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							pg	2017-11-24T13:26:42Z						biological_process											owl:Class	
GO:2000574	biolink:NamedThing	obsolete regulation of microtubule motor activity	OBSOLETE. Any process that modulates the frequency, rate or extent of microtubule motor activity.	got7fsn_ti	regulation of kinetochore motor activity|regulation of axonemal motor activity|regulation of dynein ATPase activity|regulation of dynein|regulation of kinesin motor activity|regulation of kinesin	https://github.com/geneontology/go-ontology/issues/21626			This term was obsoleted because it represents a molecular function.	GO:0140659	bf	2011-04-05T08:36:44Z		True				biological_process											owl:Class	
GO:1902976	biolink:NamedThing	premeiotic DNA replication preinitiation complex assembly	Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle.	got7fsn_ti	DNA replication preinitiation complex formation involved in meiotic cell cycle|pre-IC complex assembly involved in meiotic cell cycle						jl	2014-05-06T19:19:31Z						biological_process											owl:Class	
GO:1900462	biolink:NamedThing	obsolete negative regulation of pseudohyphal growth by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T07:01:54Z		True				biological_process											owl:Class	
GO:0033123	biolink:NamedThing	positive regulation of purine nucleotide catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.	got7fsn_ti	positive regulation of purine nucleotide degradation|positive regulation of purine nucleotide breakdown|positive regulation of purine nucleotide catabolism													biological_process											owl:Class	
GO:0009963	biolink:NamedThing	positive regulation of flavonoid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.	got7fsn_ti	positive regulation of flavonoid biosynthesis|up-regulation of flavonoid biosynthetic process|positive regulation of flavonoid formation|positive regulation of flavonoid synthesis|upregulation of flavonoid biosynthetic process|up regulation of flavonoid biosynthetic process|stimulation of flavonoid biosynthetic process|activation of flavonoid biosynthetic process|positive regulation of flavonoid anabolism													biological_process											owl:Class	
GO:1901015	biolink:NamedThing	3alpha(S)-strictosidine biosynthetic process	The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine.	got7fsn_ti	3alpha(S)-strictosidine anabolism|3alpha(S)-strictosidine synthesis|3alpha(S)-strictosidine formation|3alpha(S)-strictosidine biosynthesis						yaf	2012-06-15T10:47:26Z						biological_process											owl:Class	
GO:0036253	biolink:NamedThing	response to amiloride	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus.	got7fsn_ti							bf	2012-06-15T01:05:35Z						biological_process											owl:Class	
GO:0019382	biolink:NamedThing	carbon tetrachloride catabolic process	The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.	got7fsn_ti	carbon tetrachloride catabolism|carbon tetrachloride breakdown|carbon tetrachloride degradation													biological_process											owl:Class	
GO:1905218	biolink:NamedThing	cellular response to astaxanthin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.	got7fsn_ti	cellular response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione						sl	2016-06-06T21:30:09Z						biological_process											owl:Class	
GO:1904055	biolink:NamedThing	negative regulation of cholangiocyte proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation.	got7fsn_ti	down regulation of cholangiocyte proliferation|down regulation of hepatoblast proliferation|inhibition of hepatoblast proliferation|downregulation of hepatoblast proliferation|downregulation of cholangiocyte proliferation|inhibition of cholangiocyte proliferation|down-regulation of cholangiocyte proliferation|down-regulation of hepatoblast proliferation|negative regulation of hepatoblast proliferation						sl	2015-03-18T17:56:20Z						biological_process											owl:Class	
GO:0016806	biolink:NamedThing	obsolete dipeptidyl-peptidase and tripeptidyl-peptidase activity	OBSOLETE. Catalysis of the hydrolysis of N-terminal di- or tripeptides from a polypeptide chain.	got7fsn_ti	dipeptidyl-peptidase and tripeptidyl-peptidase activity				This term was made obsolete because it represents two activities.					True		EC:3.4.14.-		molecular_function											owl:Class	
PR:000008878	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904405	biolink:NamedThing	cellular response to formaldehyde	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.	got7fsn_ti							sl	2015-06-23T21:14:10Z						biological_process											owl:Class	
GO:0060989	biolink:NamedThing	lipid tube assembly involved in organelle fusion	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.	got7fsn_ti	lipid tubulation involved in organelle fusion						dph	2010-01-11T02:06:50Z						biological_process											owl:Class	
GO:1904183	biolink:NamedThing	negative regulation of pyruvate dehydrogenase activity	Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity.	got7fsn_ti	inhibition of pyruvate dehydrogenase activity|down-regulation of pyruvate dehydrogenase activity|downregulation of pyruvic acid dehydrogenase activity|inhibition of pyruvic acid dehydrogenase activity|downregulation of pyruvate dehydrogenase activity|negative regulation of pyruvic acid dehydrogenase activity|inhibition of pyruvic dehydrogenase activity|negative regulation of pyruvic dehydrogenase activity|down-regulation of pyruvic acid dehydrogenase activity|down regulation of pyruvic acid dehydrogenase activity|down regulation of pyruvate dehydrogenase activity|down regulation of pyruvic dehydrogenase activity|downregulation of pyruvic dehydrogenase activity|down-regulation of pyruvic dehydrogenase activity						dph	2015-05-05T14:17:33Z						biological_process											owl:Class	
CHEBI:57847	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002600	biolink:NamedThing	positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.	got7fsn_ti	upregulation of antigen processing and presentation of lipid antigen via MHC class Ib|stimulation of antigen processing and presentation of lipid antigen via MHC class Ib|up regulation of antigen processing and presentation of lipid antigen via MHC class Ib|up-regulation of antigen processing and presentation of lipid antigen via MHC class Ib|positive regulation of lipid antigen processing and presentation via MHC class Ib|activation of antigen processing and presentation of lipid antigen via MHC class Ib													biological_process											owl:Class	
GO:0002902	biolink:NamedThing	regulation of B cell apoptotic process	Any process that modulates the frequency, rate, or extent of B cell apoptotic process.	got7fsn_ti	regulation of B cell apoptosis													biological_process											owl:Class	
GO:1904003	biolink:NamedThing	negative regulation of sebum secreting cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation.	got7fsn_ti	down-regulation of sebocyte proliferation|downregulation of sebocyte proliferation|inhibition of sebum secreting cell proliferation|down regulation of sebocyte proliferation|down regulation of sebum secreting cell proliferation|negative regulation of sebocyte proliferation|downregulation of sebum secreting cell proliferation|inhibition of sebocyte proliferation|down-regulation of sebum secreting cell proliferation						hjd	2015-03-06T16:19:50Z						biological_process											owl:Class	
GO:0052148	biolink:NamedThing	modulation by symbiont of host catalytic activity	The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation by symbiont of host catalytic activity|modulation of catalytic activity of host by symbiont|modulation by symbiont of host enzyme activity|regulation of catalytic activity of host by symbiont|regulation of host catalytic activity by symbiont													biological_process											owl:Class	
GO:0009137	biolink:NamedThing	purine nucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine nucleoside diphosphate degradation|purine nucleoside diphosphate breakdown|purine nucleoside diphosphate catabolism													biological_process											owl:Class	
GO:0052221	biolink:NamedThing	obsolete positive chemotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive chemotaxis in response to environment of other organism|positive chemotaxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:2000657	biolink:NamedThing	negative regulation of apolipoprotein binding	Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.	got7fsn_ti							vk	2011-05-02T05:33:44Z						biological_process											owl:Class	
CHEBI:5019	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099170	biolink:NamedThing	postsynaptic modulation of chemical synaptic transmission	Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission.	got7fsn_ti							dos	2017-09-11T17:09:17Z						biological_process											owl:Class	
GO:1900312	biolink:NamedThing	regulation of maltohexaose transport	Any process that modulates the frequency, rate or extent of maltohexaose transport.	got7fsn_ti							tt	2012-04-05T07:59:18Z						biological_process											owl:Class	
GO:0071676	biolink:NamedThing	negative regulation of mononuclear cell migration	Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.	got7fsn_ti	down regulation of mononuclear cell migration|inhibition of mononuclear cell migration|down-regulation of mononuclear cell migration|downregulation of mononuclear cell migration						mah	2010-02-16T02:13:55Z						biological_process											owl:Class	
GO:0007085	biolink:NamedThing	obsolete nuclear membrane vesicle binding to chromatin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nuclear membrane vesicle binding to chromatin				This term was made obsolete because it represents a molecular function.	GO:0003682				True				biological_process											owl:Class	
GO:2000898	biolink:NamedThing	regulation of glucomannan catabolic process	Any process that modulates the frequency, rate or extent of glucomannan catabolic process.	got7fsn_ti	regulation of glucomannan catabolism						tt	2011-07-29T01:13:16Z						biological_process											owl:Class	
GO:0005502	biolink:NamedThing	11-cis retinal binding	Binding to 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.	got7fsn_ti	11-cis retinaldehyde binding|vitamin A binding|11-cis-retinal binding													molecular_function											owl:Class	
GO:0043288	biolink:NamedThing	apocarotenoid metabolic process	The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.	got7fsn_ti	apocarotenoid metabolism|apo carotenoid metabolic process													biological_process											owl:Class	
GO:0006815	biolink:NamedThing	obsolete sodium/potassium transport	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	sodium/potassium transport				This term was made obsolete because it is a composite term that represents two individual processes.	GO:0006814|GO:0006813				True				biological_process											owl:Class	
GO:0062168	biolink:NamedThing	negative regulation of plus-end directed microtubule sliding	Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding.	got7fsn_ti							dph	2019-11-12T17:56:47Z						biological_process											owl:Class	
GO:0120290	biolink:NamedThing	stalled replication fork localization to nuclear periphery	A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication.	got7fsn_ti	stalled replication fork localization to nuclear periphery involved in replication fork processing	https://github.com/geneontology/go-ontology/issues/20443					krc	2020-11-23T20:25:43Z						biological_process											owl:Class	
CHEBI:15734	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072710	biolink:NamedThing	response to hydroxyurea	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.	got7fsn_ti	response to HU						mah	2012-04-11T04:15:42Z						biological_process											owl:Class	
GO:0008044	biolink:NamedThing	obsolete adult behavior (sensu Insecta)	OBSOLETE. Behavior in a fully developed and mature organism, as seen in insects.	got7fsn_ti	adult behavior (sensu Insecta)			GO:0030534	This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.					True				biological_process											owl:Class	
GO:0042851	biolink:NamedThing	L-alanine metabolic process	The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.	got7fsn_ti	L-alanine metabolism													biological_process											owl:Class	
GO:1905389	biolink:NamedThing	response to leukotriene B4	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.	got7fsn_ti	response to LTB4						sl	2016-08-18T16:37:24Z						biological_process											owl:Class	
GO:1905040	biolink:NamedThing	otic placode development	The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure.	got7fsn_ti	placoda otica development|auditory placode development|octaval placode development|ear/otic placode development|octaval VIII placode development|ear placode development						bf	2016-03-10T09:30:20Z						biological_process											owl:Class	
GO:0060902	biolink:NamedThing	regulation of hair cycle by BMP signaling pathway	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle.	got7fsn_ti	regulation of hair cycle by BMP signalling pathway						dph	2009-08-13T02:45:12Z						biological_process											owl:Class	
GO:1904584	biolink:NamedThing	cellular response to polyamine macromolecule	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.	got7fsn_ti	cellular response to polyamines|cellular response to polyamine						sl	2015-08-20T14:35:32Z						biological_process											owl:Class	
GO:0080145	biolink:NamedThing	cysteine homeostasis	Any process involved in the maintenance of an internal steady state of cysteine within an organism or cell.	got7fsn_ti							dhl	2010-01-27T04:49:14Z						biological_process											owl:Class	
CHEBI:58217	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000869	biolink:NamedThing	positive regulation of estrone secretion	Any process that activates or increases the frequency, rate or extent of estrone secretion.	got7fsn_ti	positive regulation of folliculin secretion|positive regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion						bf	2011-07-26T08:50:19Z						biological_process											owl:Class	
GO:0075160	biolink:NamedThing	obsolete positive regulation of G-protein alpha subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0033137	biolink:NamedThing	negative regulation of peptidyl-serine phosphorylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.	got7fsn_ti														biological_process											owl:Class	
GO:0042839	biolink:NamedThing	D-glucuronate metabolic process	The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate.	got7fsn_ti	D-glucuronate metabolism													biological_process											owl:Class	
GO:0014726	biolink:NamedThing	negative regulation of extraocular skeletal muscle development	Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	got7fsn_ti														biological_process											owl:Class	
GO:0003702	biolink:NamedThing	obsolete RNA polymerase II transcription factor activity	OBSOLETE. Functions to initiate or regulate RNA polymerase II transcription.	got7fsn_ti	RNA polymerase II transcription factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006366|GO:0000981				True				molecular_function											owl:Class	
GO:1901841	biolink:NamedThing	regulation of high voltage-gated calcium channel activity	Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity.	got7fsn_ti	regulation of high voltage gated calcium channel activity|regulation of high voltage-dependent calcium channel activity						rl	2013-01-24T19:02:15Z						biological_process											owl:Class	
GO:2000724	biolink:NamedThing	positive regulation of cardiac vascular smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.	got7fsn_ti	positive regulation of heart vascular smooth muscle cell differentiation						vk	2011-06-08T08:48:04Z						biological_process											owl:Class	
GO:2000658	biolink:NamedThing	positive regulation of apolipoprotein binding	Any process that activates or increases the frequency, rate or extent of apolipoprotein binding.	got7fsn_ti							vk	2011-05-02T05:33:46Z						biological_process											owl:Class	
GO:1902210	biolink:NamedThing	positive regulation of bacterial-type flagellum assembly	Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly.	got7fsn_ti	up-regulation of bacterial-type flagellum assembly|up-regulation of bacterial flagellum assembly|activation of bacterial flagellum assembly|activation of bacterial-type flagellum assembly|upregulation of bacterial-type flagellum assembly|up regulation of bacterial flagellum assembly|up regulation of bacterial-type flagellum assembly|positive regulation of bacterial flagellum assembly|upregulation of bacterial flagellum assembly						jl	2013-06-11T14:20:30Z						biological_process											owl:Class	
GO:2001239	biolink:NamedThing	regulation of extrinsic apoptotic signaling pathway in absence of ligand	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.	got7fsn_ti	regulation of extrinsic apoptotic signalling pathway in absence of ligand|regulation of extrinsic apoptosis in absence of ligand|regulation of dependence receptor signaling pathway						pr	2011-11-24T01:33:18Z						biological_process											owl:Class	
GO:0106116	biolink:NamedThing	positive regulation of mitotic cohesin dsDNA (leading strand) loading	Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.	got7fsn_ti							hjd	2018-04-18T14:52:21Z						biological_process											owl:Class	
GO:0034276	biolink:NamedThing	kynurenic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.	got7fsn_ti	kynurenic acid biosynthesis|kynurenic acid anabolism|4-hydroxyquinoline-2-carboxylic acid biosynthetic process|kynurenic acid synthesis|kynurenic acid formation													biological_process											owl:Class	
GO:0031887	biolink:NamedThing	lipid droplet transport along microtubule	The directed movement of a lipid droplet along a microtubule, mediated by motor proteins.	got7fsn_ti	lipid body transport along microtubule|adiposome transport along microtubule|lipid particle transport along microtubule													biological_process											owl:Class	
GO:0001952	biolink:NamedThing	regulation of cell-matrix adhesion	Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.	got7fsn_ti														biological_process											owl:Class	
GO:0000456	biolink:NamedThing	obsolete dimethylation involved in SSU-rRNA maturation	OBSOLETE. Dimethylation of the N6 amino groups of two consecutive adenosine residues near the 3'-end of the SSU rRNA. This process has been conserved from bacteria to eukaryotes.	got7fsn_ti					The reason for obsoletion is that this term can be captured as a GO-CAM model.					True				biological_process											owl:Class	
GO:1902726	biolink:NamedThing	positive regulation of skeletal muscle satellite cell differentiation	Any process that activates or increases the frequency, rate or extent of satellite cell differentiation.	got7fsn_ti	upregulation of satellite cell differentiation|up regulation of satellite cell differentiation|activation of satellite cell differentiation|up-regulation of satellite cell differentiation						mr	2014-02-24T16:10:14Z						biological_process											owl:Class	
GO:0044140	biolink:NamedThing	obsolete negative regulation of growth of symbiont on or near host surface	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass on or near the cells or tissues of the host organism.	got7fsn_ti					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T04:31:26Z		True				biological_process											owl:Class	
GO:1903949	biolink:NamedThing	positive regulation of atrial cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential.	got7fsn_ti	activation of atrial cardiac muscle cell action potential|up regulation of atrial cardiac muscle cell action potential|up-regulation of atrial cardiac muscle cell action potential|upregulation of atrial cardiac muscle cell action potential						nc	2015-02-20T14:36:42Z						biological_process											owl:Class	
GO:0051493	biolink:NamedThing	regulation of cytoskeleton organization	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.	got7fsn_ti	regulation of cytoskeleton organization and biogenesis|regulation of cytoskeleton organisation													biological_process											owl:Class	
GO:0033146	biolink:NamedThing	regulation of intracellular estrogen receptor signaling pathway	Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.	got7fsn_ti	regulation of estrogen receptor signalling pathway|regulation of estrogen receptor signaling pathway													biological_process											owl:Class	
GO:0003363	biolink:NamedThing	lamellipodium assembly involved in ameboidal cell migration	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell.	got7fsn_ti							dph	2009-12-08T04:38:04Z						biological_process											owl:Class	
GO:0060868	biolink:NamedThing	obsolete regulation of vesicle-mediated transport involved in floral organ abscission by small GTPase mediated signal transduction	OBSOLETE. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that modulates the rate or extent of floral organ abscission.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.		dph	2009-08-12T06:52:13Z		True				biological_process											owl:Class	
GO:0034103	biolink:NamedThing	regulation of tissue remodeling	Any process that modulates the frequency, rate, or extent of tissue remodeling.	got7fsn_ti														biological_process											owl:Class	
GO:1902196	biolink:NamedThing	isovaleryl-CoA(4-) catabolic process	The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-).	got7fsn_ti	isovaleryl-CoA(4-) degradation|isovaleryl-CoA(4-) catabolism|isovaleryl-CoA(4-) breakdown						ms	2013-06-06T09:56:00Z						biological_process											owl:Class	
GO:0010975	biolink:NamedThing	regulation of neuron projection development	Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	got7fsn_ti	regulation of neurite growth|regulation of neurite biosynthesis|regulation of neurite formation|regulation of neurite development						tb	2009-06-01T10:44:45Z						biological_process											owl:Class	
GO:0014878	biolink:NamedThing	response to electrical stimulus involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.	got7fsn_ti	response to electrical stimulus involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0043613	biolink:NamedThing	isoprene catabolic process	The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8.	got7fsn_ti	hemiterpene catabolic process|hemiterpene catabolism|2-methyl-1,3-butadiene catabolic process|2-methyl-1,3-butadiene catabolism													biological_process											owl:Class	
GO:2000905	biolink:NamedThing	negative regulation of starch metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process.	got7fsn_ti	negative regulation of starch metabolism						tb	2011-07-28T11:33:17Z						biological_process											owl:Class	
GO:0090252	biolink:NamedThing	epithelium migration involved in imaginal disc-derived wing morphogenesis	The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.	got7fsn_ti							tb	2010-01-22T11:40:46Z						biological_process											owl:Class	
GO:0004179	biolink:NamedThing	obsolete membrane alanyl aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.	got7fsn_ti	CD13|particle-bound aminopeptidase activity|microsomal aminopeptidase activity|cysteinylglycinase activity|cysteinylglycine dipeptidase activity|pseudo leucine aminopeptidase activity|L-alanine aminopeptidase activity|amino-oligopeptidase activity|membrane alanyl aminopeptidase activity|membrane alanine aminopeptidase activity|alanine-specific aminopeptidase activity|alanyl aminopeptidase activity|peptidase E activity|aminopeptidase N activity|aminopeptidase M activity|membrane aminopeptidase I activity				This term was made obsolete because it represents a gene product.	GO:0008235|GO:0004177				True		MetaCyc:3.4.11.2-RXN|EC:3.4.11.2		molecular_function											owl:Class	
GO:0009181	biolink:NamedThing	purine ribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	purine ribonucleoside diphosphate degradation|purine ribonucleoside diphosphate breakdown|purine ribonucleoside diphosphate catabolism													biological_process											owl:Class	
GO:0010902	biolink:NamedThing	positive regulation of very-low-density lipoprotein particle remodeling	Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.	got7fsn_ti	positive regulation of VLDL remodeling													biological_process											owl:Class	
GO:0052444	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|modulation of defense-related symbiont SA-mediated signal transduction pathway by organism				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1901121	biolink:NamedThing	tobramycin biosynthetic process	The chemical reactions and pathways resulting in the formation of tobramycin.	got7fsn_ti	tobramycin biosynthesis|tobramycin formation|tobramycin anabolism|tobramycin synthesis						yaf	2012-07-11T03:15:51Z						biological_process											owl:Class	
GO:0016115	biolink:NamedThing	terpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.	got7fsn_ti	terpenoid breakdown|terpenoid catabolism|terpenoid degradation													biological_process											owl:Class	
GO:0010453	biolink:NamedThing	regulation of cell fate commitment	Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.	got7fsn_ti														biological_process											owl:Class	
GO:0035646	biolink:NamedThing	endosome to melanosome transport	The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.	got7fsn_ti							bf	2011-01-24T01:30:07Z						biological_process											owl:Class	
GO:1902473	biolink:NamedThing	regulation of protein localization to synapse	Any process that modulates the frequency, rate or extent of protein localization to synapse.	got7fsn_ti	regulation of protein localisation to synapse						kmv	2013-10-25T15:09:09Z						biological_process											owl:Class	
GO:0042849	biolink:NamedThing	L-sorbose biosynthetic process	The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.	got7fsn_ti	L-sorbose formation|L-sorbose anabolism|L-sorbose synthesis|L-sorbose biosynthesis													biological_process											owl:Class	
GO:1902514	biolink:NamedThing	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.	got7fsn_ti	regulation of generation of L-type calcium current						dph	2013-11-16T00:04:42Z						biological_process											owl:Class	
GO:0033875	biolink:NamedThing	ribonucleoside bisphosphate metabolic process	The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	ribonucleoside bisphosphate metabolism													biological_process											owl:Class	
GO:0030495	biolink:NamedThing	bacteriochlorophyll catabolic process	The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.	got7fsn_ti	bacteriochlorophyll breakdown|bacteriochlorophyll catabolism|bacteriochlorophyll degradation													biological_process											owl:Class	
GO:1900379	biolink:NamedThing	regulation of asperthecin biosynthetic process	Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process.	got7fsn_ti	regulation of asperthecin synthesis|regulation of asperthecin formation|regulation of asperthecin biosynthesis						di	2012-04-17T01:58:27Z						biological_process											owl:Class	
UBERON:0003068	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0101008	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to increased salt	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12739			This term was obsoleted because it represents a GO-CAM model.	GO:0000122|GO:0071472	mec			True				biological_process											owl:Class	
GO:0015316	biolink:NamedThing	obsolete nitrite/nitrate porter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nitrite/nitrate porter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0015291|GO:0015113|GO:0015112				True				molecular_function											owl:Class	
GO:0075229	biolink:NamedThing	negative regulation of encysted zoospore germination	Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination.	got7fsn_ti	negative regulation of encysted zoospore germination on or near host													biological_process											owl:Class	
GO:1904553	biolink:NamedThing	negative regulation of chemotaxis to arachidonic acid	Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid.	got7fsn_ti	inhibition of chemotaxis to arachidonic acid|downregulation of chemotaxis to arachidonic acid|down-regulation of chemotaxis to arachidonic acid|down regulation of chemotaxis to arachidonic acid						sl	2015-08-13T21:08:20Z						biological_process											owl:Class	
GO:0090324	biolink:NamedThing	negative regulation of oxidative phosphorylation	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.	got7fsn_ti							tb	2010-05-14T10:21:33Z						biological_process											owl:Class	
GO:0015435	biolink:NamedThing	obsolete ABC-type efflux permease activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ABC-type efflux permease activity				This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.	GO:0043190|GO:0042626				True				molecular_function											owl:Class	
GO:2001236	biolink:NamedThing	regulation of extrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.	got7fsn_ti	regulation of extrinsic apoptosis|regulation of extrinsic apoptotic signalling pathway						pr	2011-11-24T01:30:05Z						biological_process											owl:Class	
GO:1901263	biolink:NamedThing	positive regulation of sorocarp spore cell differentiation	Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation.	got7fsn_ti	activation of sorocarp spore cell differentiation|upregulation of sorocarp spore cell differentiation|up regulation of sorocarp spore cell differentiation|up-regulation of sorocarp spore cell differentiation						jl	2012-08-15T09:44:58Z						biological_process											owl:Class	
GO:0097236	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of zinc ions.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0034224|GO:0045944	pr	2012-02-01T09:33:11Z		True				biological_process											owl:Class	
GO:1990149	biolink:NamedThing	obsolete COPI vesicle coating	OBSOLETE. The addition of COPI proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.	got7fsn_ti	COPI vesicle coating				This term was obsoleted at the TermGenie Gatekeeper stage because COPI vesicles are formed on Golgi membranes, and the existing term 'COPI coating of Golgi vesicle ; GO:0048205' describes this process.		rb	2013-07-29T22:09:37Z		True				biological_process											owl:Class	
GO:1903519	biolink:NamedThing	regulation of mammary gland involution	Any process that modulates the frequency, rate or extent of mammary gland involution.	got7fsn_ti							dph	2014-10-06T12:01:22Z						biological_process											owl:Class	
GO:0051936	biolink:NamedThing	gamma-aminobutyric acid reuptake	The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	got7fsn_ti	GABA reuptake|gamma-aminobutyric acid import into neuron|GABA import into glial cell|GABA recycling|gamma-aminobutyric acid import into glial cell|GABA import into neuron|gamma-aminobutyric acid uptake involved in synaptic transmission|gamma-aminobutyric acid recycling|gamma-aminobutyric acid uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0052854	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035374	biolink:NamedThing	chondroitin sulfate binding	Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).	got7fsn_ti							bf	2010-03-12T10:25:34Z						molecular_function											owl:Class	
GO:0045232	biolink:NamedThing	S-layer organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria.	got7fsn_ti	S-layer organization and biogenesis|S-layer organisation													biological_process											owl:Class	
GO:0075087	biolink:NamedThing	obsolete modulation by host of symbiont G protein-coupled receptor signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by host of symbiont G-protein coupled receptor protein signal transduction				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
CHEBI:26444	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018320	biolink:NamedThing	obsolete enzyme active site formation via S-methyl-L-cysteine	OBSOLETE. The transient methylation of peptidyl-cysteine to form S-methyl-L-cysteine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:21527678.	GO:0008757				True		RESID:AA0234		biological_process											owl:Class	
GO:1900239	biolink:NamedThing	regulation of phenotypic switching	Any process that modulates the frequency, rate or extent of phenotypic switching.	got7fsn_ti	regulation of phenotypic dimorphism						di	2012-03-28T01:49:16Z						biological_process											owl:Class	
GO:0033125	biolink:NamedThing	obsolete negative regulation of GTP catabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.	got7fsn_ti	negative regulation of GTP catabolism|negative regulation of GTP breakdown|negative regulation of GTP degradation				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0034260				True				biological_process											owl:Class	
GO:0019471	biolink:NamedThing	4-hydroxyproline metabolic process	The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls.	got7fsn_ti	4-hydroxyproline metabolism													biological_process											owl:Class	
GO:0032684	biolink:NamedThing	negative regulation of fractalkine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production.	got7fsn_ti	downregulation of fractalkine production|negative regulation of CX3CL1 production|down-regulation of fractalkine production|negative regulation of fractalkine biosynthetic process|negative regulation of CX3CL1 biosynthesis|down regulation of fractalkine production|inhibition of fractalkine production	https://github.com/geneontology/go-ontology/issues/19254									GO:0050753			biological_process											owl:Class	
GO:0032958	biolink:NamedThing	inositol phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	got7fsn_ti	inositol phosphate formation|inositol phosphate synthesis|myo-inositol phosphate biosynthetic process|inositol phosphate anabolism|inositol phosphate biosynthesis													biological_process											owl:Class	
GO:0009260	biolink:NamedThing	ribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	ribonucleotide formation|ribonucleotide anabolism|ribonucleotide biosynthesis|ribonucleotide synthesis													biological_process											owl:Class	
GO:1900130	biolink:NamedThing	regulation of lipid binding	Any process that modulates the frequency, rate or extent of lipid binding.	got7fsn_ti							pm	2012-02-23T04:05:03Z						biological_process											owl:Class	
GO:0014901	biolink:NamedThing	satellite cell activation involved in skeletal muscle regeneration	The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.	got7fsn_ti														biological_process											owl:Class	
GO:1903223	biolink:NamedThing	positive regulation of oxidative stress-induced neuron death	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron death.	got7fsn_ti	positive regulation of neuron death in response to oxidative stress|up regulation of neuronal cell death in response to oxidative stress|activation of neuronal cell death in response to oxidative stress|up-regulation of neuron death in response to oxidative stress|up regulation of neuron death in response to oxidative stress|activation of neuron death in response to oxidative stress|up-regulation of oxidative stress-induced neuron death|positive regulation of neuronal cell death in response to oxidative stress|upregulation of oxidative stress-induced neuron death|up-regulation of neuronal cell death in response to oxidative stress|up regulation of oxidative stress-induced neuron death|activation of oxidative stress-induced neuron death|sensitization of neuron to oxidative stress-induced cell death|upregulation of neuronal cell death in response to oxidative stress|upregulation of neuron death in response to oxidative stress						bf	2014-07-29T08:51:52Z						biological_process											owl:Class	
GO:0002549	biolink:NamedThing	negative regulation of plasma kallikrein-kinin cascade	Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade.	got7fsn_ti	down regulation of plasma kallikrein-kinin cascade|inhibition of plasma kallikrein-kinin cascade|down-regulation of plasma kallikrein-kinin cascade|downregulation of plasma kallikrein-kinin cascade													biological_process											owl:Class	
GO:0046340	biolink:NamedThing	diacylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.	got7fsn_ti	diacylglycerol breakdown|diacylglycerol catabolism|diglyceride catabolism|diacylglycerol degradation													biological_process											owl:Class	
GO:0071950	biolink:NamedThing	FADH2 binding	Binding to the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.	got7fsn_ti	reduced flavin adenine dinucleotide binding|reduced flavine-adenine dinucleotide binding						mah	2010-10-07T12:31:34Z						molecular_function											owl:Class	
GO:0000261	biolink:NamedThing	obsolete sodium-translocating V-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in vacuoles of eukaryotes and in bacteria.	got7fsn_ti	sodium-translocating V-type ATPase activity			GO:0046962	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1901966	biolink:NamedThing	regulation of cellular response to iron ion starvation	Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation.	got7fsn_ti							al	2013-02-21T11:35:57Z						biological_process											owl:Class	
GO:0110102	biolink:NamedThing	ribulose bisphosphate carboxylase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex.	got7fsn_ti	rubisco assembly|RuBisCO assembly	https://github.com/geneontology/go-ontology/issues/19828					kmv	2018-03-15T17:24:14Z						biological_process											owl:Class	
GO:0075344	biolink:NamedThing	obsolete modulation by symbiont of host protein levels	OBSOLETE. The alteration by an organism of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it is a readout, and annotations should be made to more informative terms.					True				biological_process											owl:Class	
GO:0005559	biolink:NamedThing	obsolete ribozyme	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ribozyme				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0072717	biolink:NamedThing	cellular response to actinomycin D	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.	got7fsn_ti							mah	2012-04-26T02:06:55Z						biological_process											owl:Class	
GO:1904477	biolink:NamedThing	positive regulation of small GTPase binding	Any process that activates or increases the frequency, rate or extent of small GTPase binding.	got7fsn_ti	activation of Ras GTPase binding|up regulation of small GTPase binding|upregulation of small GTPase binding|positive regulation of Ras GTPase binding|up-regulation of small GTPase binding	https://github.com/geneontology/go-ontology/issues/18750					sl	2015-07-10T22:47:43Z						biological_process											owl:Class	
GO:0097216	biolink:NamedThing	guanosine tetraphosphate binding	Binding to guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.	got7fsn_ti	5'-ppGpp-3' binding						pr	2012-01-13T08:35:50Z						molecular_function											owl:Class	
GO:0106128	biolink:NamedThing	negative regulation of store-operated calcium entry	Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry.	got7fsn_ti							hjd	2018-05-10T18:59:12Z						biological_process											owl:Class	
GO:0097285	biolink:NamedThing	obsolete cell-type specific apoptotic process	OBSOLETE. Any apoptotic process in a specific cell type.	got7fsn_ti	cell-type specific apoptosis				This term was made obsolete because it was an unnecessary grouping term.	GO:0006915	pr	2012-03-29T04:00:25Z		True				biological_process											owl:Class	
GO:1904418	biolink:NamedThing	regulation of telomeric loop formation	Any process that modulates the frequency, rate or extent of telomeric loop formation.	got7fsn_ti	regulation of t-loop biosynthesis|regulation of t-loop formation						nc	2015-07-01T10:40:24Z						biological_process											owl:Class	
GO:2000341	biolink:NamedThing	regulation of chemokine (C-X-C motif) ligand 2 production	Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.	got7fsn_ti	chemokine (C-C motif) ligand 2 secretion|regulation of MIP2 production|regulation of SCYB2 production|regulation of CCL2 secretion|regulation of CXCL2 production|regulation of chemokine (C-C motif) ligand 2 secretion|regulation of MIP-2 production						mah	2011-02-01T11:57:14Z			GO:0035926|GO:1904207			biological_process											owl:Class	
GO:2000085	biolink:NamedThing	negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.	got7fsn_ti	negative regulation of mesonephric mesenchyme to epithelial transition						dph	2010-09-03T06:08:21Z						biological_process											owl:Class	
GO:0045775	biolink:NamedThing	positive regulation of beta 2 integrin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.	got7fsn_ti	up-regulation of beta 2 integrin biosynthetic process|positive regulation of beta 2 integrin formation|positive regulation of beta 2 integrin synthesis|positive regulation of beta 2 integrin anabolism|up regulation of beta 2 integrin biosynthetic process|positive regulation of beta 2 integrin biosynthesis|upregulation of beta 2 integrin biosynthetic process|activation of beta 2 integrin biosynthetic process|stimulation of beta 2 integrin biosynthetic process													biological_process											owl:Class	
GO:0075241	biolink:NamedThing	positive regulation of zoospore formation	Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.	got7fsn_ti														biological_process											owl:Class	
GO:0106118	biolink:NamedThing	regulation of sterol biosynthetic process	Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.	got7fsn_ti							hjd	2018-04-19T17:41:06Z						biological_process											owl:Class	
GO:2000534	biolink:NamedThing	positive regulation of renal albumin absorption	Any process that activates or increases the frequency, rate or extent of renal albumin absorption.	got7fsn_ti							pr	2011-03-24T03:28:14Z						biological_process											owl:Class	
PR:000001004	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052652	biolink:NamedThing	cyclic purine nucleotide metabolic process	The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine.	got7fsn_ti	cyclic purine nucleotide metabolism							2010-09-23T11:15:59Z						biological_process											owl:Class	
GO:0022628	biolink:NamedThing	chloroplast large ribosomal subunit	The large subunit of a ribosome contained within a chloroplast.	got7fsn_ti	chloroplast ribosomal large subunit complex|chloroplast ribosomal LSU complex													cellular_component											owl:Class	
GO:0032155	biolink:NamedThing	obsolete cell division site part	OBSOLETE. Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell.	got7fsn_ti	cell division plane part				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0032153				True				cellular_component											owl:Class	
GO:0060877	biolink:NamedThing	regionalization involved in semicircular canal formation	The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.	got7fsn_ti							dph	2009-08-13T09:56:45Z						biological_process											owl:Class	
GO:0051349	biolink:NamedThing	positive regulation of lyase activity	Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.	got7fsn_ti	lyase activator|upregulation of lyase activity|activation of lyase activity|stimulation of lyase activity|up-regulation of lyase activity|up regulation of lyase activity													biological_process											owl:Class	
GO:0050668	biolink:NamedThing	positive regulation of homocysteine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.	got7fsn_ti	activation of homocysteine metabolic process|up regulation of homocysteine metabolic process|stimulation of homocysteine metabolic process|upregulation of homocysteine metabolic process|positive regulation of homocysteine metabolism|up-regulation of homocysteine metabolic process|positive regulation of Hcy metabolism|positive regulation of Hcy metabolic process													biological_process											owl:Class	
GO:0062229	biolink:NamedThing	regulation of larval somatic muscle development	Any process that modulates the rate, frequency or extent of larval somatic muscle development.	got7fsn_ti							dph	2020-03-16T13:42:44Z						biological_process											owl:Class	
GO:0047193	biolink:NamedThing	obsolete CDP-acylglycerol O-arachidonoyltransferase activity	OBSOLETE. Catalysis of the reaction: CDP-acylglycerol + arachidonyl-CoA = CDP-diacylglycerol + CoA.	got7fsn_ti	CDPacylglycerol O-arachidonyltransferase activity|CDP-acylglycerol O-arachidonyltransferase activity|arachidonoyl-CoA:CDP-acylglycerol O-arachidonoyltransferase activity|CDP-acylglycerol O-arachidonoyltransferase activity|arachidonyl-CoA:CDP-acylglycerol O-arachidonyltransferase activity				This term was made obsolete because the evidence for the existence of this reaction was retracted. Please see PMID:6885763 for more information.					True		MetaCyc:2.3.1.70-RXN		molecular_function											owl:Class	
GO:0100066	biolink:NamedThing	obsolete negative regulation of induction of conjugation with cellular fusion by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates induction of conjugation with cellular fusion.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0062063	biolink:NamedThing	BBSome binding	Binding to a BBSome complex.	got7fsn_ti							dph	2018-08-31T13:59:18Z						molecular_function											owl:Class	
GO:1905802	biolink:NamedThing	regulation of cellular response to manganese ion	Any process that modulates the frequency, rate or extent of cellular response to manganese ion.	got7fsn_ti	regulation of cellular response to manganese						pga	2017-01-11T14:59:39Z						biological_process											owl:Class	
GO:0060697	biolink:NamedThing	positive regulation of phospholipid catabolic process	Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.	got7fsn_ti							dph	2009-06-08T02:28:38Z						biological_process											owl:Class	
GO:0010696	biolink:NamedThing	positive regulation of mitotic spindle pole body separation	Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.	got7fsn_ti	positive regulation of SPB separation													biological_process											owl:Class	
GO:0062157	biolink:NamedThing	mitochondrial ATP-gated potassium channel complex	A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.	got7fsn_ti							dph	2019-09-20T16:17:05Z						cellular_component											owl:Class	
GO:0062163	biolink:NamedThing	pseudohyphal septin ring assembly	The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection.	got7fsn_ti							dph	2019-11-07T15:46:26Z						biological_process											owl:Class	
UBERON:0002330	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000535	biolink:NamedThing	regulation of entry of bacterium into host cell	Any process that modulates the frequency, rate or extent of entry of bacterium into host cell.	got7fsn_ti	regulation of invasion of bacteria into host cell|regulation of bacterial entry into host cell						ebc	2011-03-28T09:52:16Z						biological_process											owl:Class	
GO:0019608	biolink:NamedThing	nicotine catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.	got7fsn_ti	nicotine catabolism|nicotine degradation|nicotine breakdown											UM-BBD_pathwayID:nic|MetaCyc:P181-PWY		biological_process											owl:Class	
GO:0019446	biolink:NamedThing	obsolete tyrosine catabolic process to phosphoenolpyruvate	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including phosphoenolpyruvate.	got7fsn_ti	tyrosine breakdown to phosphoenolpyruvate|tyrosine degradation to phosphoenolpyruvate				The reason for obsoletion is that there is no evidence that this is a real process.					True				biological_process											owl:Class	
GO:1901448	biolink:NamedThing	regulation of response to butan-1-ol	Any process that modulates the frequency, rate or extent of response to butan-1-ol.	got7fsn_ti							tt	2012-10-02T14:15:50Z						biological_process											owl:Class	
GO:1901000	biolink:NamedThing	regulation of response to salt stress	Any process that modulates the frequency, rate or extent of response to salt stress.	got7fsn_ti	regulation of response to ionic osmotic stress|regulation of salinity response						dhl	2012-06-14T05:41:19Z						biological_process											owl:Class	
GO:0106199	biolink:NamedThing	obsolete translocase activity acting on amino acids and peptides linked to oxidoreductase reactions	OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to oxidoreductase reactions.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:23:04Z		True		EC:7.4.1.-		molecular_function											owl:Class	
GO:0043048	biolink:NamedThing	dolichyl monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative.	got7fsn_ti	dolichyl monophosphate anabolism|dolichyl monophosphate synthesis|dolichyl monophosphate formation|dolichyl monophosphate biosynthesis													biological_process											owl:Class	
GO:0051671	biolink:NamedThing	obsolete induction of autolysin activity in other organism	OBSOLETE. Any process in which an organism initiates the activity of the inactive enzyme autolysin in another organism. The autolysin enzyme belongs to, and is active in, the other organism.	got7fsn_ti	positive regulation of autolysin activity in another organism|induction of autolytic activity in other organism|activation of autolytic activity in other organism|activation of autolysis in other organism|induction of autolysis in other organism|induction of autolysin activity in another organism|activation of autolysin activity in another organism	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1904918	biolink:NamedThing	transmembrane L-histidine transport from lysosomal lumen to cytosol	The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol.	got7fsn_ti							kmv	2016-01-21T16:27:55Z						biological_process											owl:Class	
GO:1905033	biolink:NamedThing	positive regulation of membrane repolarization during cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.	got7fsn_ti	up-regulation of membrane repolarization during cardiac muscle cell action potential|activation of membrane repolarization during cardiac muscle cell action potential|up regulation of membrane repolarization during cardiac muscle cell action potential|upregulation of membrane repolarization during cardiac muscle cell action potential						rph	2016-03-07T10:24:53Z						biological_process											owl:Class	
GO:0009222	biolink:NamedThing	pyrimidine ribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	pyrimidine ribonucleotide degradation|pyrimidine ribonucleotide catabolism|pyrimidine ribonucleotide breakdown													biological_process											owl:Class	
GO:0009133	biolink:NamedThing	nucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	nucleoside diphosphate synthesis|nucleoside diphosphate anabolism|nucleoside diphosphate formation|nucleoside diphosphate biosynthesis													biological_process											owl:Class	
GO:0006580	biolink:NamedThing	ethanolamine metabolic process	The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).	got7fsn_ti	ethanolamine metabolism										GO:0006645			biological_process											owl:Class	
GO:1900784	biolink:NamedThing	fumiquinazoline F biosynthetic process	The chemical reactions and pathways resulting in the formation of fumiquinazoline F.	got7fsn_ti	fumiquinazoline F anabolism|fumiquinazoline F formation|fumiquinazoline F synthesis|fumiquinazoline F biosynthesis						di	2012-06-04T09:31:34Z						biological_process											owl:Class	
GO:1901653	biolink:NamedThing	cellular response to peptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.	got7fsn_ti							pr	2012-11-20T09:45:19Z						biological_process											owl:Class	
GO:0062109	biolink:NamedThing	regulation of DNA recombinase disassembly	Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components.	got7fsn_ti							dph	2019-02-05T13:53:19Z						biological_process											owl:Class	
GO:0007240	biolink:NamedThing	obsolete nuclear translocation of Hog1	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nuclear translocation of Hog1				This term was made obsolete because it contains gene product and species specific information.					True				biological_process											owl:Class	
GO:0061777	biolink:NamedThing	obsolete DNA clamp activity	OBSOLETE. A DNA binding activity in which a protein complex interacts selectively and non-covalently with single DNA duplex to tightly encircle the DNA.	got7fsn_ti					The reason for obsoletion is that the term captures the structure of a complex, not a specific function.		dph	2016-07-13T13:15:24Z		True				molecular_function											owl:Class	
GO:0032811	biolink:NamedThing	negative regulation of epinephrine secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.	got7fsn_ti	downregulation of epinephrine secretion|inhibition of epinephrine secretion|down-regulation of epinephrine secretion|negative regulation of adrenaline secretion|down regulation of epinephrine secretion													biological_process											owl:Class	
GO:0004860	biolink:NamedThing	protein kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:1900241	biolink:NamedThing	positive regulation of phenotypic switching	Any process that activates or increases the frequency, rate or extent of phenotypic switching.	got7fsn_ti	activation of phenotypic dimorphism|upregulation of phenotypic switching|up-regulation of phenotypic dimorphism|up-regulation of phenotypic switching|activation of phenotypic switching|up regulation of phenotypic dimorphism|upregulation of phenotypic dimorphism|positive regulation of phenotypic dimorphism|up regulation of phenotypic switching						di	2012-03-28T01:49:34Z						biological_process											owl:Class	
GO:0016135	biolink:NamedThing	saponin biosynthetic process	The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.	got7fsn_ti	saponin biosynthesis|saponin synthesis|saponin anabolism|saponin formation													biological_process											owl:Class	
GO:0023042	biolink:NamedThing	obsolete signaling via protein/peptide mediator	OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a protein/peptide mediator.	got7fsn_ti	signalling via protein/peptide mediator|signaling via protein/peptide mediator				This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0046021	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.	got7fsn_ti	mitotic regulation of transcription from Pol II promoter|regulation of transcription from RNA polymerase II promoter during mitosis|regulation of transcription from Pol II promoter, mitotic	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0006357|GO:0044772				True				biological_process											owl:Class	
GO:0006685	biolink:NamedThing	sphingomyelin catabolic process	The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.	got7fsn_ti	sphingomyelin catabolism|sphingomyelin degradation|sphingomyelin breakdown													biological_process											owl:Class	
GO:0000098	biolink:NamedThing	sulfur amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.	got7fsn_ti	sulfur amino acid degradation|sulphur amino acid catabolic process|sulfur amino acid breakdown|sulphur amino acid catabolism|sulfur amino acid catabolism													biological_process											owl:Class	
GO:0090290	biolink:NamedThing	positive regulation of osteoclast proliferation	Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.	got7fsn_ti							tb	2010-02-18T03:11:03Z						biological_process											owl:Class	
GO:0016694	biolink:NamedThing	obsolete bacterial catalase-peroxidase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	bacterial catalase-peroxidase activity				This term was made obsolete because it represents a bifunctional gene product.	GO:0004601|GO:0004096				True				molecular_function											owl:Class	
GO:1903152	biolink:NamedThing	obsolete copper ion transmembrane transporter activity involved in copper ion import into cell	OBSOLETE. Any copper ion transmembrane transporter activity that is involved in copper ion import into cell.	got7fsn_ti	plasma membrane copper transporter involved in copper cation import into cell|copper ion transmembrane transporter activity involved in copper ion import into cell|intracellular copper ion transporter involved in copper ion import into cell|intracellular copper ion transporter involved in copper cation import into cell|plasma membrane copper transporter involved in copper ion import into cell|copper ion transmembrane transporter activity involved in copper cation import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:47Z		True				molecular_function											owl:Class	
GO:0002724	biolink:NamedThing	regulation of T cell cytokine production	Any process that modulates the frequency, rate, or extent of T cell cytokine production.	got7fsn_ti	regulation of T-cell cytokine production|regulation of T lymphocyte cytokine production|regulation of T-lymphocyte cytokine production													biological_process											owl:Class	
GO:0008565	biolink:NamedThing	obsolete protein transporter activity	OBSOLETE. Enables the directed movement of proteins into, out of or within a cell, or between cells.	got7fsn_ti	enzyme transporter activity|protein transport chaperone|secretin|holin				This term was obsoleted because is has been inconsistently used.					True				molecular_function											owl:Class	
GO:0071548	biolink:NamedThing	response to dexamethasone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.	got7fsn_ti	response to dexamethasone stimulus						mah	2010-01-13T01:24:40Z						biological_process											owl:Class	
GO:0140145	biolink:NamedThing	copper ion export from vacuole	The directed movement of copper ions out of the vacuole across the vacuolar membrane.	got7fsn_ti							pg	2017-12-13T15:02:39Z						biological_process											owl:Class	
GO:0046276	biolink:NamedThing	methylgallate catabolic process	The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.	got7fsn_ti	methylgallate catabolism|methylgallate breakdown|methylgallate degradation											MetaCyc:METHYLGALLATE-DEGRADATION-PWY		biological_process											owl:Class	
GO:1901166	biolink:NamedThing	neural crest cell migration involved in autonomic nervous system development	Any neural crest cell migration that is involved in autonomic nervous system development.	got7fsn_ti							vk	2012-07-19T08:39:56Z						biological_process											owl:Class	
GO:2000587	biolink:NamedThing	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.	got7fsn_ti	negative regulation of betaPDGF receptor signaling pathway|negative regulation of platelet-derived growth factor receptor-beta signalling pathway|negative regulation of PDGFR-beta signaling pathway|negative regulation of PDGF receptor-beta signaling pathway						bf	2011-04-07T03:27:54Z						biological_process											owl:Class	
GO:0016644	biolink:NamedThing	obsolete oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, an iron-sulfur protein, NAD, NADP or oxygen.	got7fsn_ti	oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016638				True				molecular_function											owl:Class	
GO:0050994	biolink:NamedThing	regulation of lipid catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.	got7fsn_ti	regulation of lipid breakdown|regulation of lipid degradation|regulation of lipid catabolism													biological_process											owl:Class	
CHEBI:18186	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071420	biolink:NamedThing	cellular response to histamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.	got7fsn_ti	cellular response to histamine stimulus						mah	2009-12-14T04:09:25Z						biological_process											owl:Class	
GO:0005957	biolink:NamedThing	obsolete debranching enzyme	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	debranching enzyme				This term was made obsolete because it is ambiguous (there are several debranching enzymes) and because it probably represents the glycogen debranching enzyme which is a single gene product and not a complex.	GO:0043033				True				cellular_component											owl:Class	
GO:0070452	biolink:NamedThing	positive regulation of ergosterol biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.	got7fsn_ti	up regulation of ergosterol biosynthetic process|positive regulation of ergosterol synthesis|positive regulation of ergosterol biosynthesis|activation of ergosterol biosynthetic process|up-regulation of ergosterol biosynthetic process|positive regulation of ergosterol formation|positive regulation of ergosterol anabolism|upregulation of ergosterol biosynthetic process|stimulation of ergosterol biosynthetic process													biological_process											owl:Class	
GO:2000357	biolink:NamedThing	negative regulation of kidney smooth muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation.	got7fsn_ti							yaf	2011-02-03T02:14:28Z						biological_process											owl:Class	
GO:0019575	biolink:NamedThing	obsolete sucrose catabolic process, using beta-fructofuranosidase	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose, catalyzed by the enzyme beta-fructofuranosidase (EC:3.2.1.26).	got7fsn_ti	sucrose degradation, using beta-fructofuranosidase|sucrose breakdown, using beta-fructofuranosidase|sucrose catabolic process, using beta-fructofuranosidase|sucrose catabolism, using beta-fructofuranosidase				This term was made obsolete because beta-fructofuranosidase (also known as invertase) catalyzes the first step in multiple routes of sucrose catabolism.	GO:0004564|GO:0036008				True		MetaCyc:SUCUTIL-PWY		biological_process											owl:Class	
GO:0046032	biolink:NamedThing	ADP catabolic process	The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.	got7fsn_ti	ADP breakdown|ADP degradation|ADP catabolism													biological_process											owl:Class	
GO:0016347	biolink:NamedThing	obsolete calcium-independent cell adhesion molecule activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	calcium-independent cell adhesion molecule activity				This term was made obsolete because it represents a gene product.	GO:0016338|GO:0005515|GO:0007161|GO:0016021				True				molecular_function											owl:Class	
GO:0046060	biolink:NamedThing	dATP metabolic process	The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).	got7fsn_ti	dATP metabolism													biological_process											owl:Class	
GO:0016666	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903426	biolink:NamedThing	regulation of reactive oxygen species biosynthetic process	Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process.	got7fsn_ti	regulation of reactive oxygen species biosynthesis|regulation of reactive oxygen species formation|regulation of reactive oxygen species synthesis|regulation of reactive oxygen species generation|regulation of ROS formation|regulation of ROS generation|regulation of reactive oxygen species anabolism						bf	2014-09-11T10:01:47Z						biological_process											owl:Class	
GO:1900676	biolink:NamedThing	negative regulation of F-9775B biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process.	got7fsn_ti	downregulation of F-9775B synthesis|inhibition of F-9775B biosynthetic process|down regulation of F-9775B biosynthesis|downregulation of F-9775B biosynthetic process|negative regulation of F-9775B formation|down regulation of F-9775B formation|downregulation of F-9775B anabolism|negative regulation of F-9775B anabolism|down regulation of F-9775B synthesis|down-regulation of F-9775B synthesis|downregulation of F-9775B biosynthesis|down-regulation of F-9775B biosynthetic process|inhibition of F-9775B biosynthesis|down-regulation of F-9775B biosynthesis|negative regulation of F-9775B synthesis|inhibition of F-9775B formation|down-regulation of F-9775B anabolism|negative regulation of F-9775B biosynthesis|down regulation of F-9775B biosynthetic process|down-regulation of F-9775B formation|inhibition of F-9775B anabolism|down regulation of F-9775B anabolism|downregulation of F-9775B formation|inhibition of F-9775B synthesis						di	2012-05-22T04:26:53Z						biological_process											owl:Class	
GO:0005213	biolink:NamedThing	structural constituent of egg chorion	The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster.	got7fsn_ti	structural protein of chorion|structural constituent of chorion													molecular_function											owl:Class	
GO:2000867	biolink:NamedThing	regulation of estrone secretion	Any process that modulates the frequency, rate or extent of estrone secretion.	got7fsn_ti	regulation of folliculin secretion|regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion						bf	2011-07-26T08:50:11Z						biological_process											owl:Class	
GO:2000350	biolink:NamedThing	positive regulation of CD40 signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway.	got7fsn_ti	positive regulation of CD40 signalling pathway						mah	2011-02-03T10:29:46Z						biological_process											owl:Class	
GO:1902516	biolink:NamedThing	sn-glycerol 3-phosphate binding	Binding to sn-glycerol 3-phosphate.	got7fsn_ti					An example of this is UgpB in E. coli [P0AG80] - see PMID:23013274.		bhm	2013-11-27T16:50:55Z						molecular_function											owl:Class	
GO:0009098	biolink:NamedThing	leucine biosynthetic process	The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.	got7fsn_ti	leucine biosynthesis|leucine anabolism|leucine formation|leucine synthesis											MetaCyc:LEUSYN-PWY		biological_process											owl:Class	
GO:0018065	biolink:NamedThing	obsolete protein-cofactor linkage	OBSOLETE. The covalent attachment of a cofactor to a protein.	got7fsn_ti					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group protein modification processes that are not all chemically related by the fact that they may be used as a cofactor.					True				biological_process											owl:Class	
GO:0033399	biolink:NamedThing	cis-zeatin metabolic process	The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	got7fsn_ti	cis-zeatin metabolism													biological_process											owl:Class	
GO:0019320	biolink:NamedThing	hexose catabolic process	The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.	got7fsn_ti	hexose breakdown|hexose catabolism|hexose degradation													biological_process											owl:Class	
GO:1904554	biolink:NamedThing	positive regulation of chemotaxis to arachidonic acid	Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid.	got7fsn_ti	activation of chemotaxis to arachidonic acid|up-regulation of chemotaxis to arachidonic acid|upregulation of chemotaxis to arachidonic acid|up regulation of chemotaxis to arachidonic acid						sl	2015-08-13T21:08:27Z						biological_process											owl:Class	
CHEBI:63573	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60971	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0100008	biolink:NamedThing	regulation of fever generation by prostaglandin biosynthetic process	Any prostaglandin biosynthetic process process that regulates fever generation.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
GO:0045019	biolink:NamedThing	negative regulation of nitric oxide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.	got7fsn_ti	negative regulation of nitric oxide biosynthesis|negative regulation of nitric oxide formation|down regulation of nitric oxide biosynthetic process|negative regulation of nitric oxide synthesis|negative regulation of nitric oxide anabolism|down-regulation of nitric oxide biosynthetic process|inhibition of nitric oxide biosynthetic process|downregulation of nitric oxide biosynthetic process													biological_process											owl:Class	
GO:0010821	biolink:NamedThing	regulation of mitochondrion organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.	got7fsn_ti	regulation of mitochondrion organisation													biological_process											owl:Class	
GO:1901539	biolink:NamedThing	ent-pimara-8(14),15-diene metabolic process	The chemical reactions and pathways involving ent-pimara-8(14),15-diene.	got7fsn_ti	ent-pimara-8(14),15-diene metabolism						di	2012-10-25T15:38:13Z						biological_process											owl:Class	
GO:0045799	biolink:NamedThing	positive regulation of chromatin assembly or disassembly	Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly.	got7fsn_ti	up regulation of chromatin assembly or disassembly|positive regulation of chromatin assembly/disassembly|stimulation of chromatin assembly or disassembly|up-regulation of chromatin assembly or disassembly|upregulation of chromatin assembly or disassembly|activation of chromatin assembly or disassembly													biological_process											owl:Class	
GO:0003420	biolink:NamedThing	regulation of growth plate cartilage chondrocyte proliferation	Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.	got7fsn_ti							dph	2009-12-22T09:07:40Z						biological_process											owl:Class	
GO:1901625	biolink:NamedThing	cellular response to ergosterol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus.	got7fsn_ti							dph	2012-11-14T13:53:51Z						biological_process											owl:Class	
GO:0034182	biolink:NamedThing	regulation of maintenance of mitotic sister chromatid cohesion	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0016108	biolink:NamedThing	tetraterpenoid metabolic process	The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units.	got7fsn_ti	tetraterpene metabolic process|tetraterpenoid metabolism|tetraterpene metabolism													biological_process											owl:Class	
GO:1905500	biolink:NamedThing	obsolete heteroreceptor complex assembly	OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a heteroreceptor complex.	got7fsn_ti	heteroreceptor complex formation				This term was obsoleted at the TermGenie Gatekeeper stage.		pad	2016-09-27T10:49:56Z		True				biological_process											owl:Class	
GO:0031998	biolink:NamedThing	regulation of fatty acid beta-oxidation	Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation.	got7fsn_ti														biological_process											owl:Class	
GO:0046160	biolink:NamedThing	heme a metabolic process	The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3.	got7fsn_ti	heme a metabolism|haem a metabolism|haem a metabolic process													biological_process											owl:Class	
GO:0002687	biolink:NamedThing	positive regulation of leukocyte migration	Any process that activates or increases the frequency, rate, or extent of leukocyte migration.	got7fsn_ti	up regulation of leukocyte migration|stimulation of leukocyte migration|positive regulation of leucocyte migration|upregulation of leukocyte migration|up-regulation of leukocyte migration|positive regulation of immune cell migration|activation of leukocyte migration													biological_process											owl:Class	
GO:0071327	biolink:NamedThing	cellular response to trehalose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.	got7fsn_ti							mah	2009-12-10T05:27:54Z						biological_process											owl:Class	
GO:0008533	biolink:NamedThing	obsolete astacin activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'.	got7fsn_ti	astacus proteinase activity|Astacus proteinase activity|crayfish small-molecule proteinase activity|astacin activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0038081	biolink:NamedThing	obsolete MAP kinase kinase kinase activity involved in osmosensory signaling pathway	OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.	got7fsn_ti	MAP3K activity involved in osmosensory signaling pathway|MAPKKK activity involved in osmosensory signaling pathway|MAP kinase kinase kinase activity involved in osmosensory signalling pathway				This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:41:31Z		True				molecular_function											owl:Class	
GO:1903002	biolink:NamedThing	positive regulation of lipid transport across blood-brain barrier	Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier.	got7fsn_ti	positive regulation of lipid transport across blood brain barrier|activation of lipid transport across blood brain barrier|up regulation of lipid transport across blood brain barrier|up-regulation of lipid transport across blood brain barrier|upregulation of lipid transport across blood brain barrier						sjp	2014-05-09T09:30:16Z						biological_process											owl:Class	
GO:1901310	biolink:NamedThing	positive regulation of sterol regulatory element binding protein cleavage	Any process that activates or increases the frequency, rate or extent of sterol regulatory element binding protein cleavage.	got7fsn_ti	up-regulation of sterol regulatory element binding protein cleavage|upregulation of sterol regulatory element binding protein cleavage|activation of SREBP cleavage|up-regulation of SREBP cleavage|positive regulation of SREBP cleavage|up regulation of sterol regulatory element binding protein cleavage|up regulation of SREBP cleavage|activation of sterol regulatory element binding protein cleavage|upregulation of SREBP cleavage						bf	2012-08-21T16:43:40Z						biological_process											owl:Class	
GO:1990548	biolink:NamedThing	mitochondrial FAD transmembrane transport	The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:04:35Z						biological_process											owl:Class	
GO:0106179	biolink:NamedThing	obsolete translocase activity acting on inorganic cations and their chelates	OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:45:41Z		True		EC:7.2.-.-		molecular_function											owl:Class	
GO:0010140	biolink:NamedThing	obsolete adenine, hypoxanthine and their nucleoside salvage	OBSOLETE. The pathway by which adenine, hypoxanthine and their nucleosides from purine nucleotides breakdown are converted back to purine nucleotides. The salvage pathway is important where there is no de-novo purine nucleotide biosynthesis.	got7fsn_ti	adenine, hypoxanthine and their nucleoside salvage				This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology.	GO:0006190|GO:0043103|GO:0006169|GO:0006168				True				biological_process											owl:Class	
GO:1901709	biolink:NamedThing	(+)-larreatricin metabolic process	The chemical reactions and pathways involving (+)-larreatricin.	got7fsn_ti	(+)-larreatricin metabolism						ms	2012-12-19T14:44:29Z						biological_process											owl:Class	
GO:0051160	biolink:NamedThing	L-xylitol catabolic process	The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group.	got7fsn_ti	L-xylitol degradation|L-xylitol breakdown|L-xylitol catabolism													biological_process											owl:Class	
GO:0042193	biolink:NamedThing	methylmercury catabolic process	The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal.	got7fsn_ti	methylmercury catabolism|methylmercury breakdown|methylmercury degradation													biological_process											owl:Class	
GO:0002847	biolink:NamedThing	negative regulation of T cell tolerance induction to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell.	got7fsn_ti	downregulation of T cell tolerance induction to tumor cell|down-regulation of T cell tolerance induction to tumor cell|down regulation of T cell tolerance induction to tumor cell|inhibition of T cell tolerance induction to tumor cell													biological_process											owl:Class	
GO:2000532	biolink:NamedThing	regulation of renal albumin absorption	Any process that modulates the frequency, rate or extent of renal albumin absorption.	got7fsn_ti							pr	2011-03-24T03:28:06Z						biological_process											owl:Class	
GO:0032105	biolink:NamedThing	negative regulation of response to extracellular stimulus	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus.	got7fsn_ti	down regulation of response to extracellular stimulus|inhibition of response to extracellular stimulus|downregulation of response to extracellular stimulus|down-regulation of response to extracellular stimulus													biological_process											owl:Class	
GO:1904109	biolink:NamedThing	positive regulation of cholesterol import	Any process that activates or increases the frequency, rate or extent of cholesterol import.	got7fsn_ti	up regulation of cholesterol import|upregulation of cholesterol import|activation of cholesterol import|up regulation of cholesterol uptake|upregulation of cholesterol uptake|activation of cholesterol uptake|up-regulation of cholesterol import|up-regulation of cholesterol uptake|positive regulation of cholesterol uptake						sl	2015-04-03T14:39:06Z						biological_process											owl:Class	
GO:1905308	biolink:NamedThing	cellular response to miconazole	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.	got7fsn_ti							al	2016-07-06T11:55:30Z						biological_process											owl:Class	
GO:0052127	biolink:NamedThing	obsolete movement on or near host	OBSOLETE. The directed movement of an organism or motile cell on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:0034761	biolink:NamedThing	positive regulation of iron ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	stimulation of transmembrane iron ion transport|upregulation of transmembrane iron ion transport|positive regulation of iron ion membrane transport|positive regulation of transmembrane iron transport|positive regulation of transmembrane iron ion transport|activation of transmembrane iron ion transport|up regulation of transmembrane iron ion transport|up-regulation of transmembrane iron ion transport													biological_process											owl:Class	
GO:1902884	biolink:NamedThing	positive regulation of response to oxidative stress	Any process that activates or increases the frequency, rate or extent of response to oxidative stress.	got7fsn_ti	upregulation of response to oxidative stress|up-regulation of response to oxidative stress|activation of response to oxidative stress|up regulation of response to oxidative stress						kmv	2014-04-03T20:30:47Z						biological_process											owl:Class	
GO:1905265	biolink:NamedThing	blasticidin S catabolic process	The chemical reactions and pathways resulting in the breakdown of blasticidin S.	got7fsn_ti	blasticidin S catabolism|blasticidin S breakdown|blasticidin S degradation						pr	2016-06-14T12:47:13Z						biological_process											owl:Class	
GO:0061955	biolink:NamedThing	positive regulation of actin filament depolymerization involved in acrosome reaction	Any process that increases the rate or exent of actin depolymerization as part of the acrosome reaction. This allows the acrosomal membrane and plasma membrane to fuse.	got7fsn_ti							dph	2017-11-10T19:43:18Z						biological_process											owl:Class	
GO:1903259	biolink:NamedThing	exon-exon junction complex disassembly	The disaggregation of an exon-exon junction complex into its constituent components.	got7fsn_ti	EJC disassembly						sart	2014-08-06T09:44:06Z						biological_process											owl:Class	
GO:0033535	biolink:NamedThing	ajugose metabolic process	The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	got7fsn_ti	ajugose metabolism													biological_process											owl:Class	
GO:1904313	biolink:NamedThing	response to methamphetamine hydrochloride	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.	got7fsn_ti	response to methamphetamine HCL						sl	2015-06-10T17:47:09Z						biological_process											owl:Class	
GO:0019749	biolink:NamedThing	cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte	The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.	got7fsn_ti														biological_process											owl:Class	
GO:0019535	biolink:NamedThing	ferric-vibriobactin transmembrane transporter activity	Enables the transfer of ferric-vibriobactin ions from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:1904942	biolink:NamedThing	regulation of cardiac ventricle formation	Any process that modulates the frequency, rate or extent of cardiac ventricle formation.	got7fsn_ti							bc	2016-02-02T16:37:16Z						biological_process											owl:Class	
GO:1901794	biolink:NamedThing	3-(3-hydroxyphenyl)propanoate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate.	got7fsn_ti	3-(3-hydroxyphenyl)propanoate catabolism|3-(3-hydroxyphenyl)propanoate breakdown|3-(3-hydroxyphenyl)propanoate degradation						yaf	2013-01-16T11:47:17Z						biological_process											owl:Class	
OBO:GOCHE_26013	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903179	biolink:NamedThing	regulation of dopamine biosynthetic process	Any process that modulates the frequency, rate or extent of dopamine biosynthetic process.	got7fsn_ti	regulation of dopamine synthesis|regulation of dopamine biosynthesis|regulation of dopamine anabolism|regulation of dopamine formation						bf	2014-07-14T12:17:41Z						biological_process											owl:Class	
GO:0019942	biolink:NamedThing	obsolete NEDD8 class-dependent protein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to the target protein.	got7fsn_ti	NEDD8 class-dependent protein breakdown|RUB1-dependent protein catabolic process|NEDD8 class-dependent protein catabolism|NEDD8 class-dependent protein catabolic process|RUB1-dependent protein catabolism|NEDD8 class-dependent protein degradation|RUB1-dependent protein degradation				This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction.	GO:0045116				True				biological_process											owl:Class	
CHEBI:16796	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002825	biolink:NamedThing	regulation of T-helper 1 type immune response	Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.	got7fsn_ti														biological_process											owl:Class	
GO:0039709	biolink:NamedThing	cytoplasmic capsid assembly	The assembly of a virus capsid that occurs in the cytoplasm.	got7fsn_ti							bf	2013-11-28T15:12:30Z				VZ:1950		biological_process											owl:Class	
PR:000008910	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901173	biolink:NamedThing	phytoene catabolic process	The chemical reactions and pathways resulting in the breakdown of phytoene.	got7fsn_ti	phytoene breakdown|phytoene degradation|phytoene catabolism						yaf	2012-07-19T09:48:07Z						biological_process											owl:Class	
GO:0016247	biolink:NamedThing	channel regulator activity	Bonds to and modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.	got7fsn_ti														molecular_function											owl:Class	
GO:0062066	biolink:NamedThing	PSII associated light-harvesting complex II binding	Binding to a PSII associated light-harvesting complex II.	got7fsn_ti							dph	2018-08-31T14:06:01Z						molecular_function											owl:Class	
GO:1900231	biolink:NamedThing	regulation of single-species biofilm formation on inanimate substrate	Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.	got7fsn_ti							di	2012-03-23T04:40:35Z						biological_process											owl:Class	
GO:1905032	biolink:NamedThing	negative regulation of membrane repolarization during cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.	got7fsn_ti	downregulation of membrane repolarization during cardiac muscle cell action potential|inhibition of membrane repolarization during cardiac muscle cell action potential|down-regulation of membrane repolarization during cardiac muscle cell action potential|down regulation of membrane repolarization during cardiac muscle cell action potential						rph	2016-03-07T10:24:44Z						biological_process											owl:Class	
GO:0042817	biolink:NamedThing	pyridoxal metabolic process	The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti	pyridoxal metabolism													biological_process											owl:Class	
GO:0051394	biolink:NamedThing	regulation of nerve growth factor receptor activity	Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.	got7fsn_ti	regulation of NGF receptor activity													biological_process											owl:Class	
GO:0004929	biolink:NamedThing	obsolete frizzled-2 receptor activity	OBSOLETE. Combining with to a member of the Wnt-family of signaling molecules to initiate a change in cell activity.	got7fsn_ti	frizzled-2 receptor activity			GO:0042813	This term was made obsolete because it represents a gene product rather than an activity.	GO:0007223				True				molecular_function											owl:Class	
GO:0090025	biolink:NamedThing	regulation of monocyte chemotaxis	Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.	got7fsn_ti							tb	2009-08-03T10:17:03Z						biological_process											owl:Class	
GO:1900933	biolink:NamedThing	negative regulation of nonadec-1-ene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process.	got7fsn_ti	down regulation of nonadec-1-ene metabolic process|inhibition of nonadec-1-ene metabolism|inhibition of nonadec-1-ene metabolic process|downregulation of nonadec-1-ene metabolic process|down-regulation of nonadec-1-ene metabolic process|down-regulation of nonadec-1-ene metabolism|negative regulation of nonadec-1-ene metabolism|downregulation of nonadec-1-ene metabolism|down regulation of nonadec-1-ene metabolism						tt	2012-06-14T03:11:50Z						biological_process											owl:Class	
GO:1905493	biolink:NamedThing	regulation of G-quadruplex DNA binding	Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding.	got7fsn_ti	regulation of tetraplex DNA binding|regulation of G-quartet binding|regulation of G quadruplex DNA binding|regulation of quadruplex DNA binding|regulation of G-quartet DNA binding|regulation of G-DNA binding|regulation of G quartet binding|regulation of G quartet DNA binding						ans	2016-09-26T14:53:21Z						biological_process											owl:Class	
GO:0062012	biolink:NamedThing	regulation of small molecule metabolic process	Any process that modulates the rate, frequency or extent of a small molecule metabolic process.	got7fsn_ti	regulation of small molecule metabolism						dph	2018-03-19T14:11:54Z						biological_process											owl:Class	
CHEBI:58290	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010220	biolink:NamedThing	positive regulation of vernalization response	Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.	got7fsn_ti	activation of vernalization response|up regulation of vernalization response|stimulation of vernalization response|up-regulation of vernalization response|upregulation of vernalization response													biological_process											owl:Class	
GO:1900442	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.	got7fsn_ti	up-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|up regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|activation of filamentous growth of a population of unicellular organisms in response to neutral pH|upregulation of filamentous growth of a population of unicellular organisms in response to neutral pH						di	2012-04-25T05:56:06Z						biological_process											owl:Class	
GO:0000764	biolink:NamedThing	obsolete cellular morphogenesis involved in pheromone-induced unidirectional conjugation	OBSOLETE. The change in form (cell shape and size) that contributes to sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo pheromone-induced unidirectional conjugation.	got7fsn_ti	cellular morphogenesis during pheromone-induced unidirectional|cellular morphogenesis involved in pheromone-induced unidirectional conjugation				This term was made obsolete because unidirectional conjugation occurs only in prokaryotes, which do not undergo morphogenetic changes associated with conjugation. In short, the process described by this term does not occur.					True				biological_process											owl:Class	
GO:1904496	biolink:NamedThing	positive regulation of substance P secretion, neurotransmission	Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission.	got7fsn_ti	up regulation of substance P secretion, neurotransmission|upregulation of substance P secretion, neurotransmission|up-regulation of substance P secretion, neurotransmission|activation of substance P secretion, neurotransmission						sl	2015-07-21T19:09:16Z						biological_process											owl:Class	
GO:1904356	biolink:NamedThing	regulation of telomere maintenance via telomere lengthening	Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening.	got7fsn_ti							nc	2015-06-12T16:53:16Z						biological_process											owl:Class	
GO:1900859	biolink:NamedThing	negative regulation of brevianamide F biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of brevianamide F biosynthetic process.	got7fsn_ti	down regulation of brevianamide F biosynthetic process|down-regulation of brevianamide F biosynthetic process|downregulation of brevianamide F biosynthetic process						di	2012-06-07T09:53:17Z						biological_process											owl:Class	
GO:0062173	biolink:NamedThing	brexanolone metabolic process	The chemical reactions and pathways by which living organisms transform brexanolone.	got7fsn_ti	allopregnanolone metabolism|allotetrahydroprogesterone metabolic process|allopregnanolone metabolic process|brexanolone metabolism|allotetrahydroprogesterone metabolism						dph	2019-11-18T19:42:45Z						biological_process											owl:Class	
GO:0003199	biolink:NamedThing	endocardial cushion to mesenchymal transition involved in heart valve formation	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve.	got7fsn_ti	endocardial cushion to mesenchymal transition involved in valve formation						dph	2009-10-08T01:31:21Z						biological_process											owl:Class	
GO:0019527	biolink:NamedThing	pentitol catabolic process	The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule.	got7fsn_ti	pentitol breakdown|pentitol catabolism|pentitol degradation													biological_process											owl:Class	
GO:0006714	biolink:NamedThing	sesquiterpenoid metabolic process	The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.	got7fsn_ti	sesquiterpenoid metabolism													biological_process											owl:Class	
GO:1905924	biolink:NamedThing	obsolete regulation of invadopodium assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium assembly.	got7fsn_ti	regulation of invadopodium formation				This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:38:30Z		True				biological_process											owl:Class	
GO:0018953	biolink:NamedThing	p-cymene metabolic process	The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.	got7fsn_ti	p-cymene metabolism											UM-BBD_pathwayID:pcy		biological_process											owl:Class	
GO:1904756	biolink:NamedThing	negative regulation of gut granule assembly	Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly.	got7fsn_ti	down-regulation of gut granule biogenesis|down regulation of gut granule formation|down regulation of gut granule biogenesis|downregulation of gut granule biogenesis|negative regulation of gut granule biogenesis|inhibition of gut granule biogenesis|negative regulation of gut granule formation|down-regulation of gut granule assembly|down regulation of gut granule assembly|inhibition of gut granule assembly|inhibition of gut granule formation|down-regulation of gut granule formation|downregulation of gut granule assembly|downregulation of gut granule formation						ah	2015-10-21T08:43:51Z						biological_process											owl:Class	
GO:2001060	biolink:NamedThing	D-glycero-D-manno-heptose 7-phosphate metabolic process	The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate.	got7fsn_ti	D-glycero-D-manno-heptose 7-phosphate metabolism						jl	2011-09-09T03:29:03Z						biological_process											owl:Class	
GO:1904298	biolink:NamedThing	regulation of transcytosis	Any process that modulates the frequency, rate or extent of transcytosis.	got7fsn_ti							sl	2015-06-09T22:53:26Z						biological_process											owl:Class	
GO:0071993	biolink:NamedThing	phytochelatin transport	The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.	got7fsn_ti	cadystin transport						mah	2010-10-25T01:57:55Z						biological_process											owl:Class	
GO:0036107	biolink:NamedThing	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process	The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).	got7fsn_ti	undecaprenyl phosphate alpha-L-Ara4N metabolism|4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate metabolic process						bf	2012-02-06T02:55:42Z						biological_process											owl:Class	
GO:0010886	biolink:NamedThing	positive regulation of cholesterol storage	Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti	positive regulation of cholesterol sequestration													biological_process											owl:Class	
GO:0061506	biolink:NamedThing	obsolete DNA topoisomerase type II (ATP-independent) activity	OBSOLETE. Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is not coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.	got7fsn_ti					This term was made obsolete because there is no evidence that this function exists. There are no known type II topoisomerase enzymes that are ATP-independent; as far as we know, ALL type II topoisomerase enzymes utilize hydrolysis of ATP.		dph	2013-01-23T10:41:58Z		True				molecular_function											owl:Class	
GO:0032230	biolink:NamedThing	positive regulation of synaptic transmission, GABAergic	Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).	got7fsn_ti	stimulation of synaptic transmission, GABAergic|up-regulation of synaptic transmission, GABAergic|activation of synaptic transmission, GABAergic|upregulation of synaptic transmission, GABAergic|up regulation of synaptic transmission, GABAergic													biological_process											owl:Class	
GO:1905703	biolink:NamedThing	negative regulation of inhibitory synapse assembly	Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly.	got7fsn_ti	inhibition of inhibitory synapse assembly|negative regulation of inhibitory synapse formation|downregulation of inhibitory synapse formation|down-regulation of inhibitory synapse formation|inhibition of inhibitory synapse formation|down regulation of inhibitory synapse assembly|downregulation of inhibitory synapse assembly|down-regulation of inhibitory synapse assembly|down regulation of inhibitory synapse formation						tb	2016-11-16T18:55:40Z						biological_process											owl:Class	
GO:0006052	biolink:NamedThing	N-acetylmannosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.	got7fsn_ti	N-acetylmannosamine anabolism|N-acetylmannosamine biosynthesis|N-acetylmannosamine synthesis|N-acetylmannosamine formation													biological_process											owl:Class	
GO:1904480	biolink:NamedThing	positive regulation of intestinal absorption	Any process that activates or increases the frequency, rate or extent of intestinal absorption.	got7fsn_ti	up regulation of intestinal absorption|up-regulation of intestinal absorption|upregulation of intestinal absorption|activation of intestinal absorption						rl	2015-07-13T15:59:00Z						biological_process											owl:Class	
GO:0061191	biolink:NamedThing	positive regulation of vacuole fusion, non-autophagic	Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.	got7fsn_ti							dph	2010-07-14T09:33:31Z						biological_process											owl:Class	
UBERON:0004173	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071288	biolink:NamedThing	cellular response to mercury ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.	got7fsn_ti	cellular response to mercuric ion|cellular response to mercury						mah	2009-12-10T04:06:37Z						biological_process											owl:Class	
GO:0009634	biolink:NamedThing	obsolete heavy metal sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	heavy metal sensitivity/resistance				This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.	GO:0010038				True				biological_process											owl:Class	
GO:0017021	biolink:NamedThing	obsolete myosin phosphatase myosin binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	myosin phosphatase myosin binding				This term was made obsolete because it describes the binding of myosin phosphatase to myosin, which is not a molecular function.	GO:0017022|GO:0017018				True				molecular_function											owl:Class	
GO:1904867	biolink:NamedThing	protein localization to Cajal body	A process in which a protein is transported to, or maintained in, a location within a Cajal body.	got7fsn_ti	protein localization in Cajal body|protein localisation in Cajal body|protein localisation to Cajal body						tb	2015-12-17T21:48:18Z						biological_process											owl:Class	
GO:1901113	biolink:NamedThing	erythromycin metabolic process	The chemical reactions and pathways involving erythromycin.	got7fsn_ti	erythromycin metabolism						yaf	2012-07-11T03:06:13Z						biological_process											owl:Class	
GO:0006327	biolink:NamedThing	obsolete random coil binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	random coil binding				This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:0099026	biolink:NamedThing	anchored component of presynaptic membrane	The component of the presynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti	anchored component of presynaptic plasma membrane													cellular_component											owl:Class	
GO:0002607	biolink:NamedThing	regulation of myeloid dendritic cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
CHEBI:6472	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051611	biolink:NamedThing	regulation of serotonin uptake	Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell.	got7fsn_ti	regulation of 5-hydroxytryptamine uptake|regulation of 5HT uptake|regulation of 5-HT uptake|regulation of serotonin import													biological_process											owl:Class	
GO:0006187	biolink:NamedThing	dGTP biosynthetic process from dGDP	The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate.	got7fsn_ti	dGTP synthesis from dGDP|dGTP formation from dGDP|dGTP anabolism from dGDP													biological_process											owl:Class	
GO:1901765	biolink:NamedThing	phosphinothricin catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphinothricin.	got7fsn_ti	phosphinothricin degradation|phosphinothricin catabolism|phosphinothricin breakdown						yaf	2013-01-15T10:02:42Z						biological_process											owl:Class	
GO:1905360	biolink:NamedThing	GTPase complex	A protein complex which is capable of GTPase activity.	got7fsn_ti	RASH-SOS1 complex|HRAS-SOS1 complex				An example of this is HRAS in human (P01112) in PMID:9178006 (inferred from direct assay).		bhm	2016-08-11T15:34:44Z						cellular_component											owl:Class	
GO:1905355	biolink:NamedThing	spine apparatus assembly	The aggregation, arrangement and bonding together of a set of components to form a spine apparatus.	got7fsn_ti	dense material assembly|spine apparatus formation|dense material formation						bf	2016-08-09T10:12:29Z						biological_process											owl:Class	
GO:0023055	biolink:NamedThing	obsolete signal initiation by peptide hormone	OBSOLETE. The process in which a signal is initiated by a peptide hormone.	got7fsn_ti	signal initiation by peptide hormone				This term was made obsolete because the meaning of the term is ambiguous.	GO:0005179|GO:0009755|GO:0004879		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0015531	biolink:NamedThing	citrate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).	got7fsn_ti	citrate:hydrogen symporter activity											RHEA:32123		molecular_function											owl:Class	
GO:1904377	biolink:NamedThing	positive regulation of protein localization to cell periphery	Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery.	got7fsn_ti	activation of protein localization to cell periphery|up regulation of protein localization to cell periphery|up-regulation of protein localization to cell periphery|upregulation of protein localization to cell periphery						sl	2015-06-22T22:09:37Z						biological_process											owl:Class	
GO:1900124	biolink:NamedThing	negative regulation of nodal receptor complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly.	got7fsn_ti	down regulation of nodal receptor complex assembly|inhibition of ActRIIB.ALK4.EGF-CFC complex formation|negative regulation of ActRIIB.ALK4.EGF-CFC complex formation|inhibition of nodal receptor complex assembly|down regulation of ActRIIB.ALK4.EGF-CFC complex formation|down regulation of nodal receptor complex formation|negative regulation of nodal receptor complex formation|down-regulation of ActRIIB.ALK4.EGF-CFC complex formation|down-regulation of nodal receptor complex assembly|down-regulation of nodal receptor complex formation|downregulation of nodal receptor complex formation|downregulation of nodal receptor complex assembly|inhibition of nodal receptor complex formation|downregulation of ActRIIB.ALK4.EGF-CFC complex formation						bf	2012-02-22T04:21:53Z						biological_process											owl:Class	
GO:0032083	biolink:NamedThing	negative regulation of type IV site-specific deoxyribonuclease activity	Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity.	got7fsn_ti	negative regulation of type IV restriction endodeoxyribonuclease activity|downregulation of type IV restriction endodeoxyribonuclease activity|down-regulation of type IV restriction endodeoxyribonuclease activity|type IV restriction endodeoxyribonuclease inhibitor|inhibition of type IV restriction endodeoxyribonuclease activity|type IV restriction enzyme inhibitor|down regulation of type IV restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0006060	biolink:NamedThing	sorbitol metabolic process	The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.	got7fsn_ti	sorbitol metabolism											MetaCyc:P461-PWY		biological_process											owl:Class	
GO:1902633	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process	The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	got7fsn_ti	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolism				Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name.		di	2014-01-18T00:34:27Z						biological_process											owl:Class	
GO:0006249	biolink:NamedThing	dCMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate.	got7fsn_ti	dCMP catabolism|dCMP degradation|dCMP breakdown													biological_process											owl:Class	
GO:0060664	biolink:NamedThing	epithelial cell proliferation involved in salivary gland morphogenesis	The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.	got7fsn_ti							dph	2009-06-01T08:36:13Z						biological_process											owl:Class	
CHEBI:18099	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016109	biolink:NamedThing	tetraterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.	got7fsn_ti	tetraterpenoid synthesis|tetraterpene biosynthetic process|tetraterpenoid biosynthesis|tetraterpene biosynthesis|tetraterpenoid formation|tetraterpenoid anabolism													biological_process											owl:Class	
GO:1902893	biolink:NamedThing	regulation of pri-miRNA transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.	got7fsn_ti	regulation of pri-miRNA transcription from RNA polymerase II promoter						dph	2014-04-08T13:22:08Z						biological_process											owl:Class	
GO:1905314	biolink:NamedThing	semi-lunar valve development	The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.	got7fsn_ti	semilunar valves development|semilunar valve development						rl	2016-07-11T17:50:44Z						biological_process											owl:Class	
GO:2000948	biolink:NamedThing	regulation of xyloglucan metabolic process	Any process that modulates the frequency, rate or extent of xyloglucan metabolic process.	got7fsn_ti	regulation of xyloglucan metabolism						tt	2011-08-01T02:16:54Z						biological_process											owl:Class	
GO:0097093	biolink:NamedThing	polyacyltrehalose biosynthetic process	The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.	got7fsn_ti	polyacyltrehalose synthesis|polyacyltrehalose biosynthesis|polyacyltrehalose formation|polyacyltrehalose anabolism						pr	2011-07-05T02:01:08Z						biological_process											owl:Class	
GO:0007236	biolink:NamedThing	obsolete activation of Ssk1 protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of Ssk1 protein				This term was made obsolete because it contains gene product and species specific information.					True				biological_process											owl:Class	
GO:0002658	biolink:NamedThing	regulation of peripheral tolerance induction	Any process that modulates the frequency, rate, or extent of peripheral tolerance induction.	got7fsn_ti														biological_process											owl:Class	
GO:0032072	biolink:NamedThing	regulation of restriction endodeoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.	got7fsn_ti														biological_process											owl:Class	
GO:0072704	biolink:NamedThing	response to mercaptoethanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.	got7fsn_ti	response to 2-sulfanylethanol						mah	2012-04-11T03:27:02Z						biological_process											owl:Class	
OBO:OBA_0000036	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004437	biolink:NamedThing	obsolete inositol or phosphatidylinositol phosphatase activity	OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.	got7fsn_ti	inositol or phosphatidylinositol phosphatase activity|inositol/phosphatidylinositol phosphatase activity				This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.	GO:0034594|GO:0034593|GO:0052744|GO:0052745				True				molecular_function											owl:Class	
GO:0070416	biolink:NamedThing	trehalose metabolism in response to water deprivation	The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water.	got7fsn_ti	trehalose metabolic process involved in response to water deprivation													biological_process											owl:Class	
GO:0019447	biolink:NamedThing	D-cysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.	got7fsn_ti	D-cysteine catabolism|D-cysteine breakdown|D-cysteine degradation													biological_process											owl:Class	
GO:0035424	biolink:NamedThing	obsolete MAPK import into nucleus involved in innate immune response	OBSOLETE. The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	got7fsn_ti	nuclear translocation of MAPK involved in innate immune response				The reason for obsoletion is that this term represents a GO-CAM model.	GO:0006606	bf	2010-03-29T01:29:36Z		True				biological_process											owl:Class	
GO:0019870	biolink:NamedThing	potassium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a potassium channel.	got7fsn_ti														molecular_function											owl:Class	
GO:1900322	biolink:NamedThing	negative regulation of maltotetraose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport.	got7fsn_ti	down-regulation of maltotetraose transport|inhibition of maltotetraose transport|downregulation of maltotetraose transport|down regulation of maltotetraose transport						tt	2012-04-06T01:45:45Z						biological_process											owl:Class	
GO:2001013	biolink:NamedThing	epithelial cell proliferation involved in renal tubule morphogenesis	Any epithelial cell proliferation that is involved in renal tubule morphogenesis.	got7fsn_ti							yaf	2011-08-12T11:37:29Z						biological_process											owl:Class	
GO:0050999	biolink:NamedThing	regulation of nitric-oxide synthase activity	Any process that modulates the activity of the enzyme nitric-oxide synthase.	got7fsn_ti	regulation of NOS activity|NOS regulator|nitric-oxide synthase regulator													biological_process											owl:Class	
GO:0010985	biolink:NamedThing	negative regulation of lipoprotein particle clearance	Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							tb	2009-06-01T12:06:59Z						biological_process											owl:Class	
GO:0000062	biolink:NamedThing	fatty-acyl-CoA binding	Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.	got7fsn_ti	fatty-acyl binding|fatty-acyl-coenzyme A binding	https://github.com/geneontology/go-ontology/issues/19443												molecular_function											owl:Class	
GO:1901422	biolink:NamedThing	response to butan-1-ol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus.	got7fsn_ti	process resulting in tolerance to butan-1-ol										GO:1990336			biological_process											owl:Class	
GO:1902512	biolink:NamedThing	positive regulation of apoptotic DNA fragmentation	Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.	got7fsn_ti	activation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of DNA catabolic process during apoptosis|activation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of DNA catabolic process during apoptosis|positive regulation of DNA fragmentation involved in apoptotic nuclear change|up regulation of DNA fragmentation involved in apoptotic nuclear change|activation of apoptotic DNA fragmentation|upregulation of DNA catabolism during apoptosis|up regulation of DNA catabolism during apoptosis|positive regulation of endonucleolytic DNA catabolic process involved in apoptosis|up-regulation of apoptotic DNA fragmentation|upregulation of apoptotic DNA fragmentation|upregulation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of DNA fragmentation involved in apoptotic nuclear change|up regulation of apoptotic DNA fragmentation|up-regulation of DNA catabolism during apoptosis|up regulation of DNA catabolic process during apoptosis|up regulation of endonucleolytic DNA catabolic process involved in apoptosis|activation of DNA catabolism during apoptosis|activation of DNA catabolic process during apoptosis|up-regulation of endonucleolytic DNA catabolic process involved in apoptosis|positive regulation of DNA catabolism during apoptosis|up-regulation of DNA fragmentation involved in apoptotic nuclear change|positive regulation of DNA catabolic process during apoptosis						hjd	2013-11-15T18:28:50Z						biological_process											owl:Class	
GO:0009423	biolink:NamedThing	chorismate biosynthetic process	The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.	got7fsn_ti	shikimate pathway|chorismate biosynthesis|shikimate biosynthetic process|shikimate anabolism|shikimate synthesis|chorismate synthesis|chorismate formation|chorismate anabolism|shikimate biosynthesis										GO:0033587	MetaCyc:ARO-PWY		biological_process											owl:Class	
GO:0003769	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905150	biolink:NamedThing	regulation of voltage-gated sodium channel activity	Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity.	got7fsn_ti	regulation of voltage-dependent sodium channel activity|regulation of voltage-sensitive sodium channel|regulation of voltage gated sodium channel activity|regulation of voltage-gated sodium ion channel activity						sl	2016-04-15T21:47:40Z						biological_process											owl:Class	
GO:0140579	biolink:NamedThing	obsolete oxidoreductase activity, reducing metal ions	OBSOLETE. Catalysis of an oxidation-reduction in which the metal ion is reduced.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20675			This term was obsoleted because it is an unnecessary grouping class.	GO:0016722	pg	2021-01-13T06:55:01Z		True				molecular_function											owl:Class	
GO:0035960	biolink:NamedThing	obsolete regulation of ergosterol biosynthetic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of ergosterol biosynthetic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of ergosterol biosynthetic process by regulation of transcription from Pol II promoter|regulation of ergosterol formation by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol formation by regulation of transcription from Pol II promoter|regulation of ergosterol biosynthesis by regulation of transcription from Pol II promoter|regulation of ergosterol anabolism by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol synthesis by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol synthesis by regulation of transcription from Pol II promoter|regulation of ergosterol anabolism by regulation of transcription from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:2000069	biolink:NamedThing	regulation of post-embryonic root development	Any process that modulates the frequency, rate or extent of post-embryonic root development.	got7fsn_ti							tb	2010-08-23T11:31:32Z						biological_process											owl:Class	
GO:0000186	biolink:NamedThing	obsolete activation of MAPKK activity	OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).	got7fsn_ti	activation of MAP kinase kinase activity|activation of MAP2K activity|positive regulation of MAPKK activity|activation of MAPKK activity during sporulation|activation of MAP/ERK kinase kinase	https://github.com/geneontology/go-ontology/issues/21307			This term was obsoleted because it represents a molecular function.	GO:0043539|GO:0000165				True				biological_process											owl:Class	
GO:0051165	biolink:NamedThing	2,5-dihydroxypyridine metabolic process	The chemical reactions and pathways involving 2,5-dihydroxypyridine.	got7fsn_ti	2,5-dihydroxypyridine metabolism|pyridine-2,5-diol metabolic process													biological_process											owl:Class	
GO:1900326	biolink:NamedThing	positive regulation of maltotriulose transport	Any process that activates or increases the frequency, rate or extent of maltotriulose transport.	got7fsn_ti	activation of maltotriulose transport|upregulation of maltotriulose transport|up regulation of maltotriulose transport|up-regulation of maltotriulose transport						tt	2012-04-06T01:48:25Z						biological_process											owl:Class	
GO:2001135	biolink:NamedThing	regulation of endocytic recycling	Any process that modulates the frequency, rate or extent of endocytic recycling.	got7fsn_ti	regulation of retrograde transport of endocytic vesicles						kmv	2011-10-14T03:34:36Z						biological_process											owl:Class	
GO:1905094	biolink:NamedThing	regulation of apolipoprotein A-I-mediated signaling pathway	Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.	got7fsn_ti	regulation of apolipoprotein A-I-mediated signalling pathway						bc	2016-03-31T11:33:48Z						biological_process											owl:Class	
GO:1902496	biolink:NamedThing	obsolete protein binding involved in negative regulation of telomere maintenance via telomerase	OBSOLETE. Any protein binding that is involved in negative regulation of telomere maintenance via telomerase.	got7fsn_ti	protein binding involved in down regulation of telomere maintenance via telomerase activity|protein binding involved in inhibition of telomere maintenance via telomerase|protein binding involved in downregulation of telomere maintenance via telomerase activity|protein binding involved in down-regulation of telomere maintenance via telomerase activity				The reason for obsoletion is that this should be captured as a GO-CAM model.		dph	2013-11-13T16:22:49Z		True				molecular_function											owl:Class	
GO:1901443	biolink:NamedThing	negative regulation of response to furfural	Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural.	got7fsn_ti	down regulation of response to furfural|downregulation of response to furfural|inhibition of response to furfural|down-regulation of response to furfural						tt	2012-10-02T14:10:34Z						biological_process											owl:Class	
GO:1905072	biolink:NamedThing	cardiac jelly development	The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure.	got7fsn_ti	heart cardiac jelly development						rl	2016-03-23T13:17:59Z						biological_process											owl:Class	
GO:0046313	biolink:NamedThing	phosphoarginine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine.	got7fsn_ti	phosphoarginine degradation|phosphoarginine breakdown|phosphoarginine catabolism													biological_process											owl:Class	
GO:1903782	biolink:NamedThing	regulation of sodium ion import across plasma membrane	Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane.	got7fsn_ti							nc	2015-01-07T16:48:43Z						biological_process											owl:Class	
GO:2001039	biolink:NamedThing	negative regulation of cellular response to drug	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug.	got7fsn_ti							yaf	2011-08-27T04:12:23Z						biological_process											owl:Class	
GO:0032171	biolink:NamedThing	germ tube septin cap	A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.	got7fsn_ti														cellular_component											owl:Class	
GO:0001683	biolink:NamedThing	obsolete axonemal dynein heavy chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	axonemal dynein heavy chain			GO:0005858	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:0002904	biolink:NamedThing	positive regulation of B cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.	got7fsn_ti	stimulation of B cell apoptosis|up-regulation of B cell apoptosis|upregulation of B cell apoptosis|up regulation of B cell apoptosis|positive regulation of B cell apoptosis|activation of B cell apoptosis													biological_process											owl:Class	
GO:0048354	biolink:NamedThing	mucilage biosynthetic process involved in seed coat development	The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.	got7fsn_ti	mucilage biosynthetic process during seed coat development|mucilage synthesis during seed coat development|mucilage anabolism during seed coat development|mucilage formation during seed coat development													biological_process											owl:Class	
GO:0022825	biolink:NamedThing	obsolete copper-exporting ATPase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	copper-exporting ATPase activity			GO:0043682	This term was made obsolete because it was a placeholder during work on transporter terms, and was not defined.					True				molecular_function											owl:Class	
GO:0021875	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain.	got7fsn_ti	fibroblast growth factor receptor signalling pathway in forebrain neuroblast division													biological_process											owl:Class	
GO:1904663	biolink:NamedThing	regulation of N-terminal peptidyl-methionine acetylation	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.	got7fsn_ti							vw	2015-09-07T19:18:49Z						biological_process											owl:Class	
GO:2000921	biolink:NamedThing	regulation of arabinoxylan-containing compound catabolic process	Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process.	got7fsn_ti	regulation of arabinoxylan catabolism						tt	2011-08-01T12:38:56Z						biological_process											owl:Class	
GO:0043069	biolink:NamedThing	negative regulation of programmed cell death	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.	got7fsn_ti	inhibition of programmed cell death|downregulation of programmed cell death|down-regulation of programmed cell death|negative regulation of non-apoptotic programmed cell death|down regulation of programmed cell death										GO:0043072			biological_process											owl:Class	
GO:1904101	biolink:NamedThing	response to acadesine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.	got7fsn_ti							mr	2015-03-30T22:36:26Z						biological_process											owl:Class	
GO:0070797	biolink:NamedThing	negative regulation of cleistothecium development	Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	got7fsn_ti							mah	2009-07-08T03:36:12Z						biological_process											owl:Class	
GO:2000159	biolink:NamedThing	regulation of planar cell polarity pathway involved in heart morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.	got7fsn_ti							dph	2010-10-05T01:03:22Z						biological_process											owl:Class	
GO:2000690	biolink:NamedThing	regulation of cardiac muscle cell myoblast differentiation	Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.	got7fsn_ti	regulation of myocardial precursor cell differentiation|regulation of cardiac myoblast differentiation						yaf	2011-05-25T09:08:01Z						biological_process											owl:Class	
GO:0032912	biolink:NamedThing	negative regulation of transforming growth factor beta2 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.	got7fsn_ti	negative regulation of TGF-B2 production|inhibition of transforming growth factor-beta2 production|down regulation of transforming growth factor-beta2 production|down-regulation of transforming growth factor-beta2 production|negative regulation of TGFB2 production|downregulation of transforming growth factor-beta2 production|negative regulation of transforming growth factor-beta2 production													biological_process											owl:Class	
PO:0000045	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006964	biolink:NamedThing	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.	got7fsn_ti	activation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|up-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|anti-Gram-negative bacterial peptide induction|upregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|anti-Gram-negative bacterial polypeptide induction|up regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|stimulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria													biological_process											owl:Class	
GO:2000437	biolink:NamedThing	regulation of monocyte extravasation	Any process that modulates the frequency, rate or extent of monocyte extravasation.	got7fsn_ti							bf	2011-03-04T10:24:08Z						biological_process											owl:Class	
GO:0006713	biolink:NamedThing	glucocorticoid catabolic process	The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.	got7fsn_ti	glucocorticoid catabolism|glucocorticoid degradation|glucocorticoid breakdown													biological_process											owl:Class	
GO:1903767	biolink:NamedThing	sweet taste receptor complex	A protein complex which is capable of sweet taste receptor activity.	got7fsn_ti							rl	2014-12-22T16:49:24Z						cellular_component											owl:Class	
GO:0000336	biolink:NamedThing	positive regulation of transposition, DNA-mediated	Any process that activates or increases the frequency, rate or extent of DNA transposition.	got7fsn_ti	up regulation of DNA transposition|stimulation of DNA transposition|upregulation of DNA transposition|positive regulation of DNA transposition|activation of DNA transposition|up-regulation of DNA transposition													biological_process											owl:Class	
GO:1900741	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to pH	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.	got7fsn_ti							di	2012-05-28T02:34:39Z						biological_process											owl:Class	
GO:1901415	biolink:NamedThing	positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.	got7fsn_ti	up-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|up regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|positive regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|positive regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|upregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|activation of tetrapyrrole formation from glycine and succinyl-CoA|up regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|activation of tetrapyrrole anabolism from glycine and succinyl-CoA|upregulation of tetrapyrrole synthesis from glycine and succinyl-CoA|activation of tetrapyrrole synthesis from glycine and succinyl-CoA|upregulation of tetrapyrrole formation from glycine and succinyl-CoA|up-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|upregulation of tetrapyrrole anabolism from glycine and succinyl-CoA|up-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|activation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|upregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|positive regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|up-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|positive regulation of tetrapyrrole formation from glycine and succinyl-CoA|up-regulation of tetrapyrrole formation from glycine and succinyl-CoA|up regulation of tetrapyrrole formation from glycine and succinyl-CoA|up regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|up regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|activation of tetrapyrrole biosynthesis from glycine and succinyl-CoA						tt	2012-10-01T16:29:12Z						biological_process											owl:Class	
GO:0006466	biolink:NamedThing	obsolete protein disulfide-isomerase reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	protein disulphide-isomerase reaction|protein disulfide-isomerase reaction			GO:0003756	This term was made obsolete because it presents a molecular function.					True				biological_process											owl:Class	
GO:1905853	biolink:NamedThing	regulation of heparan sulfate binding	Any process that modulates the frequency, rate or extent of heparan sulfate binding.	got7fsn_ti							bc	2017-01-23T13:25:30Z						biological_process											owl:Class	
GO:0062026	biolink:NamedThing	negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process	Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.	got7fsn_ti							dph	2018-04-16T14:02:20Z						biological_process											owl:Class	
GO:1902366	biolink:NamedThing	regulation of Notch signaling pathway involved in somitogenesis	Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.	got7fsn_ti	regulation of Notch signaling pathway involved in formation of mesodermal clusters|regulation of N signaling pathway involved in formation of mesodermal clusters|regulation of N signalling pathway involved in formation of mesodermal clusters|regulation of Notch signalling pathway involved in somitogenesis|regulation of N signalling pathway involved in somitogenesis|regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|regulation of N signaling pathway involved in somitogenesis|regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|regulation of Notch receptor signaling pathway involved in somitogenesis|regulation of Notch-receptor signaling pathway involved in somitogenesis|regulation of Notch-receptor signalling pathway involved in somitogenesis|regulation of Notch receptor signalling pathway involved in somitogenesis|regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|regulation of Notch signalling pathway involved in formation of mesodermal clusters						dph	2013-08-20T18:24:23Z						biological_process											owl:Class	
GO:0015059	biolink:NamedThing	obsolete blue-sensitive opsin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	blue-sensitive opsin				This term was made obsolete because it refers to a class of proteins.	GO:0009881|GO:0046876|GO:0007603|GO:0009588|GO:0016918|GO:0016021				True				molecular_function											owl:Class	
GO:1905319	biolink:NamedThing	mesenchymal stem cell migration	The orderly movement of a mesenchymal stem cell from one site to another.	got7fsn_ti							sl	2016-07-14T17:13:02Z						biological_process											owl:Class	
GO:0106122	biolink:NamedThing	negative regulation of cobalamin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process.	got7fsn_ti							hjd	2018-05-01T18:12:48Z						biological_process											owl:Class	
GO:1905239	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.	got7fsn_ti	regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation						rph	2016-06-08T10:26:33Z						biological_process											owl:Class	
GO:0001807	biolink:NamedThing	regulation of type IV hypersensitivity	Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response.	got7fsn_ti														biological_process											owl:Class	
UBERON:0002530	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000583	biolink:NamedThing	regulation of platelet-derived growth factor receptor-alpha signaling pathway	Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.	got7fsn_ti	regulation of alphaPDGF receptor signaling pathway|regulation of platelet-derived growth factor receptor-alpha signalling pathway|regulation of PDGFR-alpha signaling pathway|regulation of PDGF receptor-alpha signaling pathway						bf	2011-04-07T03:26:25Z						biological_process											owl:Class	
GO:0032952	biolink:NamedThing	regulation of (1->3)-beta-D-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans.	got7fsn_ti	regulation of 1,3-beta-glucan metabolic process|regulation of (1->3)-beta-D-glucan metabolism|regulation of 1,3-beta-glucan metabolism|regulation of 1,3-beta-D-glucan metabolic process													biological_process											owl:Class	
GO:0008125	biolink:NamedThing	obsolete pancreatic elastase I activity	OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. Preferential cleavage: Ala-Xaa.	got7fsn_ti	elaszym|pancreatopeptidase E activity|pancreatic elastase I activity|serine elastase			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0042980	biolink:NamedThing	obsolete cystic fibrosis transmembrane conductance regulator binding	OBSOLETE. Binding to a Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein.	got7fsn_ti	CFTR binding|cystic fibrosis transmembrane conductance regulator binding			GO:0044325	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:2000975	biolink:NamedThing	positive regulation of pro-B cell differentiation	Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation.	got7fsn_ti	positive regulation of pro-B cell development|positive regulation of pro-B lymphocyte differentiation						yaf	2011-08-02T03:05:53Z						biological_process											owl:Class	
GO:0045340	biolink:NamedThing	mercury ion binding	Binding to a mercury ion (Hg).	got7fsn_ti	mercury binding|Hg ion binding													molecular_function											owl:Class	
GO:0033594	biolink:NamedThing	response to hydroxyisoflavone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0061425	biolink:NamedThing	positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process.	got7fsn_ti							dph	2012-02-02T01:12:36Z						biological_process											owl:Class	
GO:0036376	biolink:NamedThing	sodium ion export across plasma membrane	The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	sodium ion export from cell|sodium export|sodium ion export						mah	2009-12-16T11:13:55Z			GO:0098667|GO:0071436			biological_process											owl:Class	
GO:0015442	biolink:NamedThing	obsolete hydrogen-/sodium-translocating ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + (Na+ or H+)(in) = ADP + phosphate + (Na+ or H+)(out).	got7fsn_ti	proton-/sodium-translocating ATPase activity|hydrogen-/sodium-translocating ATPase activity				This term was made obsolete because it is a redundant grouping term based on a TC-DB classification.	GO:0008554|GO:0008553				True				molecular_function											owl:Class	
GO:1903169	biolink:NamedThing	regulation of calcium ion transmembrane transport	Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.	got7fsn_ti	regulation of calcium ion membrane transport|regulation of transmembrane calcium transport				human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol		rl	2014-07-11T17:09:26Z						biological_process											owl:Class	
GO:2000423	biolink:NamedThing	negative regulation of eosinophil chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis.	got7fsn_ti							bf	2011-02-24T01:17:12Z						biological_process											owl:Class	
GO:0021876	biolink:NamedThing	Notch signaling pathway involved in forebrain neuroblast division	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.	got7fsn_ti	Notch signalling pathway in forebrain neuroblast division													biological_process											owl:Class	
GO:0085003	biolink:NamedThing	obsolete interaction with host via secreted substance released from stylet	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the stylet, a hollow protrusible spear-like structure in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T02:53:56Z		True				biological_process											owl:Class	
GO:1904261	biolink:NamedThing	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.	got7fsn_ti	up-regulation of basement membrane assembly involved in embryonic body morphogenesis|upregulation of basement membrane assembly involved in embryonic body morphogenesis|up regulation of basement membrane assembly involved in embryonic body morphogenesis|activation of basement membrane assembly involved in embryonic body morphogenesis						als	2015-05-21T09:20:55Z						biological_process											owl:Class	
GO:0032234	biolink:NamedThing	obsolete regulation of calcium ion transport via store-operated calcium channel activity	OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.	got7fsn_ti	regulation of calcium transport via store-operated calcium channel|regulation of store-operated calcium channel activity|regulation of calcium ion transport via store-operated calcium channel activity				This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0015279				True				biological_process											owl:Class	
GO:1902438	biolink:NamedThing	response to vanadate(3-)	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.	got7fsn_ti							di	2013-10-10T10:50:21Z						biological_process											owl:Class	
GO:0005532	biolink:NamedThing	obsolete mannose binding lectin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	mannose receptor|mannose binding lectin				This term was made obsolete because it refers to a class of gene products.	GO:0005537|GO:0007157				True				molecular_function											owl:Class	
GO:0015258	biolink:NamedThing	obsolete gluconate channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	gluconate channel activity				This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True				molecular_function											owl:Class	
GO:0042355	biolink:NamedThing	L-fucose catabolic process	The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).	got7fsn_ti	L-fucose degradation|L-fucose catabolism|L-fucose breakdown													biological_process											owl:Class	
GO:0062061	biolink:NamedThing	TAP complex binding	Binding to a TAP complex.	got7fsn_ti							dph	2018-08-31T13:54:22Z						molecular_function											owl:Class	
GO:1902314	biolink:NamedThing	hydroquinone binding	Binding to hydroquinone.	got7fsn_ti	quinol binding						bhm	2013-07-22T10:10:12Z						molecular_function											owl:Class	
GO:0052779	biolink:NamedThing	amino disaccharide metabolic process	The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.	got7fsn_ti								2011-10-03T08:47:05Z						biological_process											owl:Class	
GO:1903885	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 20 production	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.	got7fsn_ti	down regulation of chemokine (C-C motif) ligand 20 production|negative regulation of C-C motif chemokine 20 production|down-regulation of CCL-20 production|inhibition of chemokine (C-C motif) ligand 20 production|down regulation of CCL20 production|inhibition of CCL20 production|inhibition of C-C motif chemokine 20 production|down-regulation of chemokine (C-C motif) ligand 20 production|down regulation of C-C motif chemokine 20 production|down-regulation of C-C motif chemokine 20 production|downregulation of CCL-20 production|down regulation of CCL-20 production|downregulation of C-C motif chemokine 20 production|inhibition of CCL-20 production|negative regulation of CCL-20 production|downregulation of CCL20 production|downregulation of chemokine (C-C motif) ligand 20 production|down-regulation of CCL20 production|negative regulation of CCL20 production						krc	2015-02-06T16:31:11Z						biological_process											owl:Class	
GO:0000408	biolink:NamedThing	EKC/KEOPS complex	A protein complex involved in t6A tRNA modification. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.	got7fsn_ti	endopeptidase-like kinase chromatin-associated protein complex|TCTC|KEOPS/EKC complex|threonyl-carbamoly transferase complex|kinase, putative endopeptidase and other proteins of small size protein complex				Originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation.									cellular_component											owl:Class	
GO:0072157	biolink:NamedThing	epithelial cell migration involved in distal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.	got7fsn_ti							mah	2010-02-24T02:33:33Z						biological_process											owl:Class	
CL:0002129	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904890	biolink:NamedThing	negative regulation of excitatory synapse assembly	Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly.	got7fsn_ti	inhibition of excitatory synapse formation|down regulation of excitatory synapse formation|downregulation of excitatory synapse assembly|down regulation of excitatory synapse assembly|downregulation of excitatory synapse formation|down-regulation of excitatory synapse formation|negative regulation of excitatory synapse formation|down-regulation of excitatory synapse assembly|inhibition of excitatory synapse assembly						bf	2016-01-07T14:36:00Z						biological_process											owl:Class	
GO:1901558	biolink:NamedThing	response to metformin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus.	got7fsn_ti							hp	2012-11-02T09:46:24Z						biological_process											owl:Class	
GO:1901768	biolink:NamedThing	carbapenem catabolic process	The chemical reactions and pathways resulting in the breakdown of carbapenem.	got7fsn_ti	carbapenem degradation|carbapenem catabolism|carbapenem breakdown						yaf	2013-01-15T10:09:02Z						biological_process											owl:Class	
GO:0006585	biolink:NamedThing	dopamine biosynthetic process from tyrosine	The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine.	got7fsn_ti	dopamine synthesis from tyrosine|dopamine anabolism from tyrosine|dopamine formation from tyrosine													biological_process											owl:Class	
CL:0000034	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090556	biolink:NamedThing	phosphatidylserine floppase activity	Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	ATPase-coupled phosphatidylserine transporter activity|phosphatidylserine floppase activity (cytosolic to exoplasmic leaftlet)|phosphatidylserine-translocating ATPase activity|ATPase-dependent phosphatidylserine transporter activity						tb	2013-10-24T16:07:20Z				RHEA:38567		molecular_function											owl:Class	
GO:0150107	biolink:NamedThing	positive regulation of protein localization to cell-cell junction	Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction.	got7fsn_ti							bc	2019-06-11T11:23:58Z						biological_process											owl:Class	
GO:0044148	biolink:NamedThing	obsolete positive regulation of growth of symbiont involved in interaction with host	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.	got7fsn_ti	positive regulation of growth of symbiont during interaction with host				This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-06T02:20:27Z		True				biological_process											owl:Class	
GO:0070831	biolink:NamedThing	basement membrane assembly	The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.	got7fsn_ti					Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer.		mah	2009-07-23T05:01:51Z						biological_process											owl:Class	
GO:0000260	biolink:NamedThing	obsolete hydrogen-translocating V-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + H(+)(in) = ADP + phosphate + H+(out). Found in vacuoles of eukaryotes and in bacteria.	got7fsn_ti	hydrogen-translocating V-type ATPase activity			GO:0046961	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
UBERON:4000162	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010024	biolink:NamedThing	phytochromobilin biosynthetic process	The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha.	got7fsn_ti	phytochromobilin anabolism|phytochromobilin formation|phytochromobilin synthesis|phytochromobilin biosynthesis													biological_process											owl:Class	
GO:0044700	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:23943	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018882	biolink:NamedThing	(+)-camphor metabolic process	The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.	got7fsn_ti	camphor metabolism|camphor metabolic process|(+)-camphor metabolism											UM-BBD_pathwayID:cam		biological_process											owl:Class	
GO:0100051	biolink:NamedThing	obsolete positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates meiotic nuclear division.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:2000970	biolink:NamedThing	regulation of detection of glucose	Any process that modulates the frequency, rate or extent of detection of glucose.	got7fsn_ti	regulation of glucose sensing|regulation of glucose perception|regulation of glucose detection						vk	2011-08-02T10:18:52Z						biological_process											owl:Class	
GO:1904909	biolink:NamedThing	positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.	got7fsn_ti	positive regulation of maintenance of sister chromatin cohesion at telomere at mitosis|up-regulation of maintenance of sister chromatin cohesion at telomere at mitosis|activation of maintenance of sister chromatin cohesion at telomere at mitosis|up-regulation of maintenance of mitotic sister chromatid cohesion, telomeric|up regulation of maintenance of telomeric mitotic sister chromatin cohesion|upregulation of maintenance of mitotic sister chromatin cohesion at telomere|up regulation of maintenance of mitotic sister chromatin cohesion at telomere|upregulation of maintenance of sister chromatin cohesion at telomere at mitosis|up regulation of maintenance of mitotic sister chromatid cohesion, telomeric|activation of maintenance of mitotic sister chromatin cohesion at telomere|activation of maintenance of telomeric mitotic sister chromatin cohesion|positive regulation of maintenance of mitotic sister chromatin cohesion at telomere|upregulation of maintenance of mitotic sister chromatid cohesion, telomeric|activation of maintenance of mitotic sister chromatid cohesion, telomeric|positive regulation of maintenance of telomeric mitotic sister chromatin cohesion|up regulation of maintenance of sister chromatin cohesion at telomere at mitosis|up-regulation of maintenance of mitotic sister chromatin cohesion at telomere|up-regulation of maintenance of telomeric mitotic sister chromatin cohesion|upregulation of maintenance of telomeric mitotic sister chromatin cohesion						rph	2016-01-19T10:30:43Z						biological_process											owl:Class	
GO:1903269	biolink:NamedThing	ornithine carbamoyltransferase inhibitor complex	A protein complex which is capable of ornithine carbamoyltransferase inhibitor activity.	got7fsn_ti	OTC-ARGI complex|ornithine carbamoyltransferase arginase complex				An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay).		bhm	2014-08-08T08:47:38Z						cellular_component											owl:Class	
GO:0031106	biolink:NamedThing	septin ring organization	Control of the formation, spatial distribution, and breakdown of the septin ring.	got7fsn_ti	septin ring organisation													biological_process											owl:Class	
GO:0043085	biolink:NamedThing	positive regulation of catalytic activity	Any process that activates or increases the activity of an enzyme.	got7fsn_ti	activation of metalloenzyme activity|up regulation of enzyme activity|stimulation of enzyme activity|upregulation of metalloenzyme activity|positive regulation of metalloenzyme activity|up-regulation of metalloenzyme activity|stimulation of metalloenzyme activity|positive regulation of enzyme activity|up regulation of metalloenzyme activity|upregulation of enzyme activity|activation of enzyme activity|up-regulation of enzyme activity										GO:0048554			biological_process											owl:Class	
GO:1904433	biolink:NamedThing	negative regulation of ferrous iron binding	Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding.	got7fsn_ti	inhibition of ferrous iron binding|downregulation of ferrous iron binding|down-regulation of ferrous iron binding|down regulation of ferrous iron binding						kom	2015-07-06T13:46:36Z						biological_process											owl:Class	
GO:0075282	biolink:NamedThing	negative regulation of uredinium development	Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.	got7fsn_ti														biological_process											owl:Class	
GO:1903388	biolink:NamedThing	regulation of synaptic vesicle uncoating	Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating.	got7fsn_ti	regulation of synaptic vesicle coat protein depolymerization|regulation of synaptic vesicle coat depolymerization						pad	2014-08-27T10:02:53Z						biological_process											owl:Class	
PR:000009182	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003003	biolink:NamedThing	follicular fluid formation in ovarian follicle antrum involved in fused antrum stage	The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis.	got7fsn_ti	follicular fluid formation in ovarian follicle antrum during fused antrum stage													biological_process											owl:Class	
GO:2001115	biolink:NamedThing	methanopterin-containing compound metabolic process	The chemical reactions and pathways involving a methanopterin.	got7fsn_ti	methanopterin metabolism						jl	2011-10-11T11:54:56Z						biological_process											owl:Class	
CHEBI:46398	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901775	biolink:NamedThing	mitomycin C metabolic process	The chemical reactions and pathways involving mitomycin C.	got7fsn_ti	mitomycin C metabolism						yaf	2013-01-15T12:11:48Z						biological_process											owl:Class	
GO:0033074	biolink:NamedThing	pinene catabolic process	The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.	got7fsn_ti	pinene breakdown|pinene degradation|pinene catabolism													biological_process											owl:Class	
GO:0010640	biolink:NamedThing	regulation of platelet-derived growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.	got7fsn_ti	regulation of platelet-derived growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0009124	biolink:NamedThing	nucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	nucleoside monophosphate biosynthesis|nucleoside monophosphate anabolism|nucleoside monophosphate synthesis|nucleoside monophosphate formation													biological_process											owl:Class	
GO:0032125	biolink:NamedThing	micronucleus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus.	got7fsn_ti	micronuclear organization and biogenesis|micronucleus organisation|micronuclear organization													biological_process											owl:Class	
GO:0046637	biolink:NamedThing	regulation of alpha-beta T cell differentiation	Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation.	got7fsn_ti	regulation of alpha-beta T lymphocyte differentiation|regulation of alpha-beta T-cell differentiation|regulation of alpha-beta T-lymphocyte differentiation|regulation of alpha-beta T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0030799	biolink:NamedThing	obsolete regulation of cyclic nucleotide metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.	got7fsn_ti	regulation of cyclic nucleotide metabolism				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:1901787	biolink:NamedThing	benzoyl-CoA metabolic process	The chemical reactions and pathways involving benzoyl-CoA.	got7fsn_ti	benzoyl-CoA metabolism						yaf	2013-01-16T11:13:54Z						biological_process											owl:Class	
GO:0052540	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont cell wall thickening	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of defense-related symbiont cell wall thickening|positive regulation by organism of symbiont defensive cell wall thickening				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1902818	biolink:NamedThing	ethyl acetate metabolic process	The chemical reactions and pathways involving ethyl acetate.	got7fsn_ti	ethyl acetate metabolism|ethyl ethanoate metabolic process						tt	2014-03-30T20:26:47Z						biological_process											owl:Class	
GO:1903605	biolink:NamedThing	cytochrome biosynthetic process	The chemical reactions and pathways resulting in the formation of a cytochrome.	got7fsn_ti	cytochrome formation|cytochrome anabolism|cytochrome biosynthesis|cytochrome synthesis						dph	2014-11-13T20:01:18Z						biological_process											owl:Class	
GO:0048831	biolink:NamedThing	regulation of shoot system development	Any process that modulates the frequency, rate or extent of shoot development.	got7fsn_ti	regulation of shoot development													biological_process											owl:Class	
GO:0106114	biolink:NamedThing	regulation of mitotic cohesin dsDNA (leading strand) loading	Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.	got7fsn_ti							hjd	2018-04-18T14:48:13Z						biological_process											owl:Class	
GO:0023053	biolink:NamedThing	obsolete signal initiation by mechanical effect	OBSOLETE. The process in which a mechanical signal causes activation of a receptor.	got7fsn_ti	signal initiation by mechanical effect				This term was made obsolete because the meaning of the term is ambiguous.	GO:0007165|GO:0071260|GO:0038023		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:2000083	biolink:NamedThing	negative regulation of L-ascorbic acid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process.	got7fsn_ti	negative regulation of ascorbate biosynthesis|negative regulation of L-ascorbic acid synthesis|negative regulation of vitamin C biosynthetic process|negative regulation of L-ascorbic acid anabolism|negative regulation of ascorbate biosynthetic process|negative regulation of L-ascorbic acid formation|negative regulation of vitamin C biosynthesis|negative regulation of L-ascorbic acid biosynthesis						tb	2010-08-27T11:26:19Z						biological_process											owl:Class	
GO:0009212	biolink:NamedThing	pyrimidine deoxyribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside triphosphate formation|pyrimidine deoxyribonucleoside triphosphate anabolism|pyrimidine deoxyribonucleoside triphosphate synthesis|pyrimidine deoxyribonucleoside triphosphate biosynthesis													biological_process											owl:Class	
GO:0031920	biolink:NamedThing	pyridoxal transport	The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0019611	biolink:NamedThing	4-toluenecarboxylate metabolic process	The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.	got7fsn_ti	p-toluate metabolism|p-toluate metabolic process|4-toluenecarboxylate metabolism													biological_process											owl:Class	
GO:1903606	biolink:NamedThing	cytochrome c metabolic process	The chemical reactions and pathways involving cytochrome c.	got7fsn_ti	cytochrome c metabolism						dph	2014-11-13T20:01:27Z						biological_process											owl:Class	
GO:2001247	biolink:NamedThing	positive regulation of phosphatidylcholine biosynthetic process	Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process.	got7fsn_ti	positive regulation of phosphatidylcholine synthesis|positive regulation of phosphatidylcholine anabolism|positive regulation of phosphatidylcholine biosynthesis|positive regulation of phosphatidylcholine formation						tb	2011-11-28T09:47:54Z						biological_process											owl:Class	
GO:1901987	biolink:NamedThing	regulation of cell cycle phase transition	Any process that modulates the frequency, rate or extent of cell cycle phase transition.	got7fsn_ti	regulation of cell cycle transition|cell cycle control						jl	2013-03-19T16:11:27Z						biological_process											owl:Class	
GO:0019267	biolink:NamedThing	asparagine biosynthetic process from cysteine	The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine.	got7fsn_ti	asparagine anabolism from cysteine|asparagine formation from cysteine|asparagine synthesis from cysteine											MetaCyc:ASPSYNII-PWY		biological_process											owl:Class	
GO:0019394	biolink:NamedThing	glucarate catabolic process	The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid.	got7fsn_ti	glucarate catabolism|glucarate degradation|glucarate breakdown											MetaCyc:GLUCARDEG-PWY		biological_process											owl:Class	
GO:0051380	biolink:NamedThing	norepinephrine binding	Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.	got7fsn_ti	noradrenaline binding													molecular_function											owl:Class	
GO:1902767	biolink:NamedThing	isoprenoid biosynthetic process via mevalonate	The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate.	got7fsn_ti	isoprenoid anabolism via mevalonate|isoprenoid biosynthesis via mevalonate|isoprenoid synthesis via mevalonate|isoprenoid formation via mevalonate						tt	2014-03-10T23:45:10Z						biological_process											owl:Class	
OBO:GOCHE_33290	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048779	biolink:NamedThing	negative regulation of erythrophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation.	got7fsn_ti	down regulation of erythrophore differentiation|inhibition of erythrophore differentiation|downregulation of erythrophore differentiation|down-regulation of erythrophore differentiation													biological_process											owl:Class	
GO:2000593	biolink:NamedThing	negative regulation of metanephric DCT cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation.	got7fsn_ti	negative regulation of metanephric distal convoluted tubule cell differentiation						yaf	2011-04-11T01:40:38Z						biological_process											owl:Class	
GO:0085000	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type V secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type V secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:08:54Z		True				biological_process											owl:Class	
GO:1903544	biolink:NamedThing	response to butyrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.	got7fsn_ti							mr	2014-10-17T13:57:25Z						biological_process											owl:Class	
GO:0075204	biolink:NamedThing	obsolete negative regulation of symbiont penetration hypha formation for entry into host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18779			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1904991	biolink:NamedThing	negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.	got7fsn_ti	negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|inhibition of adenylate cyclase-inhibiting dopamine receptor signaling pathway|negative regulation of dopamine receptor, adenylate cyclase inhibiting pathway|inhibition of dopamine receptor, adenylyl cyclase inhibiting pathway|down-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|downregulation of dopamine receptor, adenylyl cyclase inhibiting pathway|down regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|inhibition of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down regulation of dopamine receptor, adenylate cyclase inhibiting pathway|negative regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|downregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|inhibition of dopamine receptor, adenylate cyclase inhibiting pathway|down regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|downregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down-regulation of dopamine receptor, adenylate cyclase inhibiting pathway|downregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|downregulation of dopamine receptor, adenylate cyclase inhibiting pathway|down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|inhibition of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway						kmv	2016-02-29T22:42:25Z						biological_process											owl:Class	
GO:2000763	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process	Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process.	got7fsn_ti	positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthesis|positive regulation of transcription from Pol II promoter involved in norepinephrine formation|positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthetic process|positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthesis|positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthetic process|positive regulation of transcription from Pol II promoter involved in levarterenol biosynthetic process|positive regulation of transcription from Pol II promoter involved in norepinephrine synthesis|positive regulation of transcription from Pol II promoter involved in norepinephrine anabolism|positive regulation of transcription from Pol II promoter involved in levarterenol biosynthesis						vk	2011-06-18T04:14:58Z						biological_process											owl:Class	
GO:1900463	biolink:NamedThing	negative regulation of cellular response to alkaline pH by negative regulation of transcription from RNA polymerase II promoter	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular response to alkalinity by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of cellular response to basic pH by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular response to alkalinity by negative regulation of transcription from RNA polymerase II promoter						dgf	2012-05-01T07:22:50Z						biological_process											owl:Class	
GO:0046065	biolink:NamedThing	dCTP metabolic process	The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate.	got7fsn_ti	dCTP metabolism													biological_process											owl:Class	
GO:0015342	biolink:NamedThing	obsolete zinc, iron permease activity	OBSOLETE. Catalysis of the reaction: (Zn2+ or Fe2+)(out) = (Zn2+ or Fe2+)(in), probably powered by proton motive force.	got7fsn_ti	zinc, iron permease activity				This term was made obsolete because it represents more than one molecular function.	GO:0005381|GO:0005385				True				molecular_function											owl:Class	
GO:0003079	biolink:NamedThing	obsolete positive regulation of natriuresis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of natriuresis.	got7fsn_ti	positive regulation of natriuresis				This term was made obsolete because its definition was inaccurate.	GO:0035815				True				biological_process											owl:Class	
GO:0010155	biolink:NamedThing	regulation of proton transport	Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0017063	biolink:NamedThing	obsolete phosphatidylserine-specific phospholipase A1 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a fatty acid anion.	got7fsn_ti	phosphatidylserine-specific phospholipase A1 activity				This term was made obsolete because the definition does not match the term name.	GO:0052740|GO:0052739				True				molecular_function											owl:Class	
GO:0016919	biolink:NamedThing	obsolete nardilysin activity	OBSOLETE. Catalysis of the hydrolysis of polypeptides, preferably at the first bond of Xaa-Arg-Lys, and less commonly at the first bond of Arg-Arg-Xaa, in which Xaa is not Arg or Lys.	got7fsn_ti	nardilysin activity|N-arginine dibasic convertase activity|NRD convertase activity|NRD-convertase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1902288	biolink:NamedThing	regulation of defense response to oomycetes	Any process that modulates the frequency, rate or extent of defense response to oomycetes.	got7fsn_ti							ms	2013-07-09T13:45:32Z						biological_process											owl:Class	
GO:0052051	biolink:NamedThing	obsolete interaction with host via protein secreted by type II secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type II secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0072481	biolink:NamedThing	obsolete detection of stimulus involved in mitotic spindle orientation checkpoint	OBSOLETE. The series of events in which information about whether the spindle is correctly oriented is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle orientation checkpoint.	got7fsn_ti	mitotic cell cycle spindle orientation checkpoint sensor mechanism|mitotic cell cycle spindle orientation checkpoint sensor process|sensing involved in mitotic cell cycle spindle orientation checkpoint|detection of stimulus involved in mitotic cell cycle spindle orientation checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T12:11:52Z		True				biological_process											owl:Class	
GO:0051863	biolink:NamedThing	obsolete translocation of DNA into symbiont	OBSOLETE. The directed movement of DNA from an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	translocation of DNA into symbiont				This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
GO:0048684	biolink:NamedThing	positive regulation of collateral sprouting of intact axon in response to injury	Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon.	got7fsn_ti	activation of collateral sprouting of intact axon in response to injury|up-regulation of collateral sprouting of intact axon in response to injury|up regulation of collateral sprouting of intact axon in response to injury|stimulation of collateral sprouting of intact axon in response to injury|upregulation of collateral sprouting of intact axon in response to injury													biological_process											owl:Class	
GO:0075033	biolink:NamedThing	obsolete appressorium septum formation	OBSOLETE. The process in which a symbiont partition is formed to separate the appressorium from the germination tube, occurring during appressorium formation.	got7fsn_ti	septum formation involved in appressorium formation on or near host|septum formation involved in appressorium formation|septum formation during appressorium formation on or near host	https://github.com/geneontology/go-ontology/issues/20305|https://github.com/geneontology/go-ontology/issues/21923			The reason for obsoletion is that there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1901431	biolink:NamedThing	regulation of response to cycloalkane	Any process that modulates the frequency, rate or extent of response to cycloalkane.	got7fsn_ti							tt	2012-10-01T21:01:58Z						biological_process											owl:Class	
GO:2001278	biolink:NamedThing	positive regulation of leucine biosynthetic process	Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process.	got7fsn_ti	positive regulation of leucine synthesis|positive regulation of leucine biosynthesis|positive regulation of leucine formation|positive regulation of leucine anabolism						mcc	2011-12-13T03:13:42Z						biological_process											owl:Class	
CHEBI:12777	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006158	biolink:NamedThing	obsolete deoxyadenosine deaminase reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	deoxyadenosine deaminase reaction			GO:0046936	This term was made obsolete because it represents a molecular function.					True				biological_process											owl:Class	
GO:0071561	biolink:NamedThing	nucleus-vacuole junction	An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.	got7fsn_ti	NVJ|nucleus-vacuole membrane contact site|NV junction						mah	2010-01-20T02:09:42Z						cellular_component											owl:Class	
GO:1905328	biolink:NamedThing	plant septum development	The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure.	got7fsn_ti	dissepiment development						tb	2016-07-21T18:25:49Z						biological_process											owl:Class	
GO:1903577	biolink:NamedThing	cellular response to L-arginine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.	got7fsn_ti							mr	2014-10-29T22:18:54Z						biological_process											owl:Class	
GO:0042153	biolink:NamedThing	obsolete RPTP-like protein binding	OBSOLETE. Binding to proteins with similar structure/function to receptor protein tyrosine phosphatases.	got7fsn_ti	receptor protein tyrosine phosphatase-like protein binding|RPTP-like protein binding			GO:0005515	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
CHEBI:22506	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044436	biolink:NamedThing	obsolete thylakoid part	OBSOLETE. Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009579				True				cellular_component											owl:Class	
GO:1904107	biolink:NamedThing	protein localization to microvillus membrane	A process in which a protein is transported to, or maintained in, a location within a microvillus membrane.	got7fsn_ti	protein localisation to microvillus membrane|protein localization in microvillus membrane|protein localisation in microvillus membrane						kmv	2015-04-01T18:14:48Z						biological_process											owl:Class	
GO:0051069	biolink:NamedThing	galactomannan metabolic process	The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units.	got7fsn_ti	galactomannan metabolism													biological_process											owl:Class	
GO:1905288	biolink:NamedThing	vascular associated smooth muscle cell apoptotic process	Any apoptotic process in a vascular associated smooth muscle cell.	got7fsn_ti	VSMC apoptotic process|vascular smooth muscle cell apoptotic process|vascular smooth muscle cell apoptosis|VSMC apoptosis|vascular associated smooth muscle cell apoptosis						rph	2016-06-23T13:24:20Z						biological_process											owl:Class	
GO:1900359	biolink:NamedThing	positive regulation of nigerotriose transport	Any process that activates or increases the frequency, rate or extent of nigerotriose transport.	got7fsn_ti	up-regulation of nigerotriose transport|upregulation of nigerotriose transport|up regulation of nigerotriose transport|activation of nigerotriose transport						tt	2012-04-06T02:18:29Z						biological_process											owl:Class	
SO:0000871	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034275	biolink:NamedThing	kynurenic acid metabolic process	The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.	got7fsn_ti	kynurenic acid metabolism|4-hydroxyquinoline-2-carboxylic acid metabolic process													biological_process											owl:Class	
GO:0019326	biolink:NamedThing	nitrotoluene metabolic process	The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.	got7fsn_ti	nitrotoluene metabolism													biological_process											owl:Class	
GO:1900083	biolink:NamedThing	obsolete regulation of Sertoli cell proliferation	OBSOLETE. Any process that modulates the frequency, rate or extent of Sertoli cell proliferation.	got7fsn_ti	regulation of Sertoli cell proliferation				This term was obsoleted at the TermGenie Gatekeeper stage.		pr	2012-02-02T03:10:50Z		True				biological_process											owl:Class	
GO:1904294	biolink:NamedThing	positive regulation of ERAD pathway	Any process that activates or increases the frequency, rate or extent of ERAD pathway.	got7fsn_ti	activation of ERAD pathway|activation of endoplasmic reticulum-associated protein degradation pathway|upregulation of endoplasmic reticulum-associated degradation|upregulation of ERAD pathway|positive regulation of endoplasmic reticulum-associated degradation|positive regulation of endoplasmic reticulum-associated protein degradation pathway|upregulation of endoplasmic reticulum-associated protein degradation pathway|up regulation of ERAD pathway|activation of endoplasmic reticulum-associated degradation|activation of ER-associated degradation pathway|up regulation of ER-associated degradation pathway|up regulation of endoplasmic reticulum-associated degradation|up-regulation of ER-associated degradation pathway|upregulation of ER-associated degradation pathway|up-regulation of ERAD pathway|up regulation of endoplasmic reticulum-associated protein degradation pathway|up-regulation of endoplasmic reticulum-associated degradation|up-regulation of endoplasmic reticulum-associated protein degradation pathway|positive regulation of ER-associated degradation pathway						bf	2015-06-09T14:44:39Z						biological_process											owl:Class	
GO:0004892	biolink:NamedThing	obsolete B cell receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	B cell receptor activity				This term was made obsolete because it describes the receptor type, and not an activity.	GO:0003823				True				molecular_function											owl:Class	
GO:1900147	biolink:NamedThing	regulation of Schwann cell migration	Any process that modulates the frequency, rate or extent of Schwann cell migration.	got7fsn_ti							bf	2012-03-06T04:14:50Z						biological_process											owl:Class	
UBERON:0000062	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009874	biolink:NamedThing	obsolete sporophytic self-incompatibility	OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place.	got7fsn_ti	sporophytic self-incompatibility				This term was made obsolete because it represents a phenotype.					True				biological_process											owl:Class	
GO:0005209	biolink:NamedThing	obsolete plasma protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	plasma protein				This term was made obsolete because it describes presence in body fluids rather than an activity.					True				molecular_function											owl:Class	
GO:0036247	biolink:NamedThing	phytochelatin 3 import into vacuole	The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.	got7fsn_ti	PC3 import into vacuole						bf	2012-05-31T11:11:03Z						biological_process											owl:Class	
GO:0019504	biolink:NamedThing	stachydrine catabolic process	The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.	got7fsn_ti	stachydrine catabolism|stachydrine breakdown|stachydrine degradation											MetaCyc:P561-PWY		biological_process											owl:Class	
GO:0035276	biolink:NamedThing	ethanol binding	Binding to ethanol, CH(3)-CH(2)-OH.	got7fsn_ti														molecular_function											owl:Class	
GO:0019015	biolink:NamedThing	obsolete viral genome	OBSOLETE. The whole of the genetic information of a virus, contained as either DNA or RNA.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:0150065	biolink:NamedThing	regulation of deacetylase activity	Any process that modulates the frequency, rate or extent of deacetylase activity.	got7fsn_ti							bc	2018-07-23T12:24:28Z						biological_process											owl:Class	
GO:0001574	biolink:NamedThing	ganglioside biosynthetic process	The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.	got7fsn_ti	ganglioside biosynthesis|ganglioside formation|ganglioside anabolism|ganglioside synthesis													biological_process											owl:Class	
GO:2000868	biolink:NamedThing	negative regulation of estrone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion.	got7fsn_ti	negative regulation of folliculin secretion|negative regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion						bf	2011-07-26T08:50:16Z						biological_process											owl:Class	
GO:0021774	biolink:NamedThing	retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification	The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.	got7fsn_ti	retinoic acid receptor signalling pathway involved in ventral spinal cord interneuron specification													biological_process											owl:Class	
GO:0032417	biolink:NamedThing	positive regulation of sodium:proton antiporter activity	Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).	got7fsn_ti	up regulation of sodium:hydrogen antiporter activity|activation of sodium:hydrogen antiporter activity|stimulation of sodium:hydrogen antiporter activity|up-regulation of sodium:hydrogen antiporter activity|upregulation of sodium:hydrogen antiporter activity|positive regulation of sodium:hydrogen antiporter activity													biological_process											owl:Class	
GO:0090372	biolink:NamedThing	positive regulation of glycerol transport	Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2010-07-12T11:30:22Z						biological_process											owl:Class	
GO:1905842	biolink:NamedThing	cellular response to oxidopamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.	got7fsn_ti							pr	2017-01-19T09:49:12Z						biological_process											owl:Class	
GO:0033129	biolink:NamedThing	positive regulation of histone phosphorylation	Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.	got7fsn_ti														biological_process											owl:Class	
GO:0009909	biolink:NamedThing	regulation of flower development	Any process that modulates the frequency, rate or extent of flower development.	got7fsn_ti														biological_process											owl:Class	
GO:0003683	biolink:NamedThing	obsolete lamin/chromatin binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lamin/chromatin binding				This term was made obsolete because it represents two functions.	GO:0003682|GO:0005521				True				molecular_function											owl:Class	
GO:0033133	biolink:NamedThing	positive regulation of glucokinase activity	Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.	got7fsn_ti	glucokinase activator|up regulation of glucokinase activity|up-regulation of glucokinase activity|stimulation of glucokinase activity|upregulation of glucokinase activity													biological_process											owl:Class	
GO:2001149	biolink:NamedThing	negative regulation of dipeptide transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport.	got7fsn_ti	negative regulation of dipeptide membrane transport						kmv	2011-10-21T06:09:59Z						biological_process											owl:Class	
GO:2001082	biolink:NamedThing	inulin binding	Binding to inulin.	got7fsn_ti							jl	2011-09-15T01:23:59Z						molecular_function											owl:Class	
GO:2000186	biolink:NamedThing	negative regulation of phosphate transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.	got7fsn_ti	negative regulation of phosphate membrane transport						vw	2010-10-15T11:33:08Z						biological_process											owl:Class	
GO:0001307	biolink:NamedThing	obsolete extrachromosomal circular DNA accumulation involved in replicative cell aging	OBSOLETE. Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.	got7fsn_ti	extrachromosomal circular DNA accumulation during replicative cell ageing|extrachromosomal circular DNA accumulation during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0071239	biolink:NamedThing	cellular response to streptomycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.	got7fsn_ti							mah	2009-12-03T02:25:59Z						biological_process											owl:Class	
GO:0150166	biolink:NamedThing	regulation of histone H3-K4 acetylation	Any process that modulates the frequency, rate or extent of histone H3-K4 acetylation.	got7fsn_ti							bc	2020-01-14T12:27:26Z						biological_process											owl:Class	
CHEBI:27996	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000153	biolink:NamedThing	obsolete regulation of flagellar cell motility	OBSOLETE. Any process that modulates the frequency, rate or extent of flagellar cell motility.	got7fsn_ti	regulation of flagellar cell motility				This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:1902021|GO:1902019	mah	2010-10-04T12:41:02Z		True				biological_process											owl:Class	
GO:1902635	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	got7fsn_ti	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation				Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name.		di	2014-01-18T00:34:45Z						biological_process											owl:Class	
GO:0003762	biolink:NamedThing	obsolete histone-specific chaperone activity	OBSOLETE. Assists in chromatin assembly by chaperoning histones on to replicating DNA, but is not a component of the assembled nucleosome when performing its normal biological function.	got7fsn_ti	nucleosome assembly chaperone|histone-specific chaperone activity				This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function.	GO:0051082|GO:0006333|GO:0034728|GO:0043486|GO:0042393|GO:0006334|GO:0044183				True				molecular_function											owl:Class	
GO:0043606	biolink:NamedThing	formamide metabolic process	The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid.	got7fsn_ti	formamide metabolism													biological_process											owl:Class	
GO:1905786	biolink:NamedThing	positive regulation of anaphase-promoting complex-dependent catabolic process	Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.	got7fsn_ti							vw	2017-01-09T10:16:33Z						biological_process											owl:Class	
GO:1905667	biolink:NamedThing	negative regulation of protein localization to endosome	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.	got7fsn_ti	down regulation of protein localization to endosome|negative regulation of protein localization in endosome|downregulation of protein localisation in endosome|inhibition of protein localization in endosome|down-regulation of protein localisation in endosome|down regulation of protein localization in endosome|inhibition of protein localization to endosome|down-regulation of protein localization to endosome|downregulation of protein localization in endosome|down-regulation of protein localization in endosome|downregulation of protein localization to endosome|negative regulation of protein localisation in endosome|inhibition of protein localisation in endosome|down regulation of protein localisation in endosome						bc	2016-11-11T11:19:09Z						biological_process											owl:Class	
GO:0060383	biolink:NamedThing	positive regulation of DNA strand elongation	Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.	got7fsn_ti														biological_process											owl:Class	
GO:0001721	biolink:NamedThing	obsolete intermediate filament associated protein	OBSOLETE. Proteins that associate with intermediate filaments and function in the supramolecular organization of cellular intermediate filament networks.	got7fsn_ti	IFAP|intermediate filament associated protein			GO:0005882	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:1900624	biolink:NamedThing	negative regulation of monocyte aggregation	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation.	got7fsn_ti	downregulation of mononuclear phagocyte aggregation|down regulation of monocyte aggregation|down regulation of mononuclear phagocyte aggregation|downregulation of monocyte aggregation|negative regulation of mononuclear phagocyte aggregation|inhibition of monocyte aggregation|inhibition of mononuclear phagocyte aggregation|down-regulation of monocyte aggregation|down-regulation of mononuclear phagocyte aggregation						vk	2012-05-21T01:07:37Z						biological_process											owl:Class	
GO:1902313	biolink:NamedThing	positive regulation of copper ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport.	got7fsn_ti	up regulation of copper ion membrane transport|up-regulation of copper ion transmembrane transport|positive regulation of copper ion membrane transport|upregulation of copper ion transmembrane transport|upregulation of copper cation transmembrane transport|upregulation of copper ion membrane transport|up regulation of copper ion transmembrane transport|up regulation of copper cation transmembrane transport|up-regulation of copper ion membrane transport|activation of copper ion transmembrane transport|positive regulation of copper cation transmembrane transport|activation of copper cation transmembrane transport|up-regulation of copper cation transmembrane transport|activation of copper ion membrane transport						di	2013-07-19T20:59:45Z						biological_process											owl:Class	
GO:2000204	biolink:NamedThing	negative regulation of ribosomal large subunit export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus.	got7fsn_ti	negative regulation of 60S ribosomal subunit export from nucleus|negative regulation of ribosomal large subunit export out of nucleus|negative regulation of 50S ribosomal subunit export from nucleus|negative regulation of ribosomal large subunit export from cell nucleus|negative regulation of ribosomal large subunit-nucleus export|negative regulation of ribosomal large subunit transport from nucleus to cytoplasm						mah	2010-10-26T10:52:39Z						biological_process											owl:Class	
GO:0005073	biolink:NamedThing	obsolete common-partner SMAD protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	common-partner SMAD protein				This term was made obsolete because it names a family of gene products.					True				molecular_function											owl:Class	
GO:0015859	biolink:NamedThing	intracellular nucleoside transport	The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.	got7fsn_ti														biological_process											owl:Class	
GO:2000411	biolink:NamedThing	negative regulation of thymocyte migration	Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration.	got7fsn_ti	negative regulation of immature T-lymphocyte migration|negative regulation of immature T-cell migration|negative regulation of immature T lymphocyte migration|negative regulation of thymic lymphocyte migration|negative regulation of immature T cell migration						mah	2011-02-23T01:34:01Z						biological_process											owl:Class	
GO:1900879	biolink:NamedThing	(Z)-nonadeca-1,14-diene biosynthetic process	The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene.	got7fsn_ti	(Z)-nonadeca-1,14-diene biosynthesis|(Z)-nonadeca-1,14-diene synthesis|(Z)-nonadeca-1,14-diene formation|(Z)-nonadeca-1,14-diene anabolism						tt	2012-06-13T02:09:39Z						biological_process											owl:Class	
GO:0006504	biolink:NamedThing	obsolete C-terminal protein geranylgeranylation	OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl group to the carboxy-terminus of a protein.	got7fsn_ti	C-terminal protein geranylgeranylation			GO:0018344	This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein.					True				biological_process											owl:Class	
GO:1900025	biolink:NamedThing	negative regulation of substrate adhesion-dependent cell spreading	Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.	got7fsn_ti	negative regulation of substrate adhesion dependent cell spreading|negative regulation of cell spreading during cell substrate adhesion|down regulation of substrate adhesion-dependent cell spreading|down regulation of substrate adhesion dependent cell spreading|down regulation of cell spreading during cell substrate adhesion						yaf	2012-01-12T05:00:43Z						biological_process											owl:Class	
GO:1903156	biolink:NamedThing	obsolete guanine transmembrane transporter activity involved in guanine import into cell	OBSOLETE. Any guanine transmembrane transporter activity that is involved in guanine import into cell.	got7fsn_ti	guanine transmembrane transporter activity involved in guanine import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:10Z		True				molecular_function											owl:Class	
GO:1903953	biolink:NamedThing	negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.	got7fsn_ti	down regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|negative regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|down-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|downregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|inhibition of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|downregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|inhibition of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|down regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|down-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization						nc	2015-02-24T10:32:16Z						biological_process											owl:Class	
GO:0050784	biolink:NamedThing	cocaine catabolic process	The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.	got7fsn_ti	cocaine breakdown|cocaine degradation|cocaine catabolism													biological_process											owl:Class	
GO:0002912	biolink:NamedThing	negative regulation of lymphocyte anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.	got7fsn_ti	inhibition of lymphocyte anergy|down regulation of lymphocyte anergy|down-regulation of lymphocyte anergy|downregulation of lymphocyte anergy													biological_process											owl:Class	
UBERON:0002371	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140487	biolink:NamedThing	metal ion sequestering activity	The selective interaction of a protein with a metal ion to prevent it from interacting with sensitive components of a biological system.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19700					pg	2020-06-29T09:23:47Z						molecular_function											owl:Class	
GO:0010170	biolink:NamedThing	glucose-1-phosphate adenylyltransferase complex	Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits.	got7fsn_ti														cellular_component											owl:Class	
GO:0075195	biolink:NamedThing	negative regulation of haustorium mother cell formation	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of haustorium mother cell formation on or near host				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0052424	biolink:NamedThing	obsolete modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system	OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type III secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0052574	biolink:NamedThing	UDP-galactose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	UDP-D-galactose biosynthesis|UDP-galactose biosynthesis|UDP-D-galactopyranose biosynthesis|UDP-D-galactose biosynthetic process|uridine diphosphate galactose biosynthesis|uridine diphosphate galactose biosynthetic process|UDP-D-galactopyranose biosynthetic process							2010-07-23T03:52:40Z						biological_process											owl:Class	
GO:1900167	biolink:NamedThing	negative regulation of glial cell-derived neurotrophic factor production	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production.	got7fsn_ti	negative regulation of glial cell-derived neurotrophic factor secretion|negative regulation of GDNF secretion|inhibition of GDNF secretion|inhibition of glial cell line-derived neurotrophic factor secretion|negative regulation of glial cell line-derived neurotrophic factor secretion						yaf	2012-03-08T03:44:43Z						biological_process											owl:Class	
GO:1903235	biolink:NamedThing	positive regulation of calcium ion-dependent exocytosis of neurotransmitter	Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.	got7fsn_ti	upregulation of calcium ion-dependent exocytosis of neurotransmitter|up-regulation of calcium ion-dependent exocytosis of neurotransmitter|up regulation of calcium ion-dependent exocytosis of neurotransmitter|activation of calcium ion-dependent exocytosis of neurotransmitter				An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP)		pad	2014-07-31T11:54:46Z						biological_process											owl:Class	
GO:1905196	biolink:NamedThing	obsolete positive regulation of ATPase activity, uncoupled	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATPase activity, uncoupled.	got7fsn_ti	up-regulation of adenylpyrophosphatase activity|activation of ATPase activity, uncoupled|up regulation of ATPase activity, uncoupled|upregulation of ATPase activity, uncoupled|positive regulation of adenylpyrophosphatase activity|up-regulation of ATPase activity, uncoupled|upregulation of adenylpyrophosphatase activity|activation of adenylpyrophosphatase activity|up regulation of adenylpyrophosphatase activity				The reason for obsoletion is that the there is no convincing example of a protein with this function.		al	2016-05-12T08:01:28Z		True				biological_process											owl:Class	
GO:0042618	biolink:NamedThing	poly-hydroxybutyrate metabolic process	The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.	got7fsn_ti	PHB metabolism|PHB metabolic process|poly-hydroxybutyrate metabolism													biological_process											owl:Class	
GO:1901120	biolink:NamedThing	tobramycin catabolic process	The chemical reactions and pathways resulting in the breakdown of tobramycin.	got7fsn_ti	tobramycin breakdown|tobramycin catabolism|tobramycin degradation						yaf	2012-07-11T03:15:43Z						biological_process											owl:Class	
GO:0090170	biolink:NamedThing	regulation of Golgi inheritance	Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.	got7fsn_ti							tb	2009-12-11T10:21:59Z						biological_process											owl:Class	
GO:1901945	biolink:NamedThing	miltiradiene catabolic process	The chemical reactions and pathways resulting in the breakdown of miltiradiene.	got7fsn_ti	miltiradiene degradation|miltiradiene breakdown|miltiradiene catabolism						ms	2013-02-18T15:50:27Z						biological_process											owl:Class	
GO:1904134	biolink:NamedThing	negative regulation of convergent extension involved in rhombomere morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.	got7fsn_ti	down regulation of convergent extension involved in rhombomere morphogenesis|downregulation of convergent extension involved in rhombomere morphogenesis|inhibition of convergent extension involved in rhombomere morphogenesis|down-regulation of convergent extension involved in rhombomere morphogenesis						dph	2015-04-10T21:21:18Z						biological_process											owl:Class	
GO:0034030	biolink:NamedThing	ribonucleoside bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	ribonucleoside bisphosphate formation|ribonucleoside bisphosphate anabolism|ribonucleoside bisphosphate biosynthesis|ribonucleoside bisphosphate synthesis													biological_process											owl:Class	
GO:0033199	biolink:NamedThing	obsolete inositol heptakisphosphate 4-kinase or 6-kinase activity	OBSOLETE. Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.	got7fsn_ti	inositol heptakisphosphate 4-kinase or 6-kinase activity				This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0000834|GO:0000833				True				molecular_function											owl:Class	
GO:0090625	biolink:NamedThing	mRNA cleavage involved in gene silencing by siRNA	The process in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.	got7fsn_ti							tb	2015-01-21T17:15:13Z						biological_process											owl:Class	
GO:0018871	biolink:NamedThing	1-aminocyclopropane-1-carboxylate metabolic process	The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.	got7fsn_ti	1-aminocyclopropane-1-carboxylate metabolism|ACP metabolism|ACP metabolic process											UM-BBD_pathwayID:acp		biological_process											owl:Class	
GO:0060092	biolink:NamedThing	regulation of synaptic transmission, glycinergic	Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.	got7fsn_ti														biological_process											owl:Class	
GO:0006912	biolink:NamedThing	obsolete phagosome formation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	phagosome formation				This term was made obsolete because of the ambiguity in its meaning.	GO:0001845|GO:0006911				True				biological_process											owl:Class	
GO:0007397	biolink:NamedThing	obsolete histogenesis and organogenesis	OBSOLETE. The generation of organized tissues or of whole organs.	got7fsn_ti	histogenesis and organogenesis				This term was made obsolete because more appropriate terms were created.	GO:0009888|GO:0009887				True				biological_process											owl:Class	
GO:1905948	biolink:NamedThing	ABC-type 3',5'-cyclic GMP transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out).	got7fsn_ti	ATPase-coupled cGMP transmembrane transporter activity|ATP-dependent 3',5'-cyclic GMP transmembrane transporter activity|3',5'-cyclic GMP transmembrane-transporting ATPase activity|ATPase-coupled 3',5'-cyclic GMP transmembrane transporter activity						ha	2017-02-16T15:54:51Z						molecular_function											owl:Class	
GO:0042057	biolink:NamedThing	obsolete transforming growth factor beta receptor anchoring activity	OBSOLETE. Binds to transforming growth factor beta receptor and anchors it to a particular subcellular location.	got7fsn_ti	TGFbeta receptor anchoring activity|transforming growth factor beta receptor anchor activity|transforming growth factor beta receptor anchoring activity|TGF-beta receptor anchoring activity				This term was made obsolete because it represents a combination of process and function information.	GO:0008104|GO:0005160				True				molecular_function											owl:Class	
GO:1902198	biolink:NamedThing	3-methylbut-2-enoyl-CoA(4-) metabolic process	The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-).	got7fsn_ti	3-methylbut-2-enoyl-CoA(4-) metabolism						ms	2013-06-06T09:56:11Z						biological_process											owl:Class	
CHEBI:64558	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030829	biolink:NamedThing	obsolete regulation of cGMP catabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.	got7fsn_ti	regulation of cGMP breakdown|regulation of cGMP catabolism|regulation of cGMP degradation				The reason for obsoletion is that this term represent the regulation of a signaling pathway,  not regulation of metabolism.					True				biological_process											owl:Class	
GO:0004215	biolink:NamedThing	obsolete cathepsin H activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds, acting as an aminopeptidase (notably, cleaving Arg-Xaa bonds) as well as an endopeptidase.	got7fsn_ti	N-benzoylarginine-beta-naphthylamide hydrolase activity|cathepsin H activity|cathepsin B3 activity|aleurain activity|cathepsin BA activity|cathepsin Ba|benzoylarginine-naphthylamide (BANA) hydrolase activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0033236	biolink:NamedThing	obsolete 11-beta-hydroxysteroid dehydrogenase (NAD+) activity	OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.	got7fsn_ti	11-beta-hydroxysteroid dehydrogenase (NAD+) activity			GO:0070523						True				molecular_function											owl:Class	
GO:1901904	biolink:NamedThing	tyrocidine biosynthetic process	The chemical reactions and pathways resulting in the formation of tyrocidine.	got7fsn_ti	tyrocidine biosynthesis|tyrocidine synthesis|tyrocidine formation|tyrocidine anabolism						yaf	2013-02-12T23:40:43Z						biological_process											owl:Class	
GO:0048400	biolink:NamedThing	positive regulation of intermediate mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification.	got7fsn_ti	upregulation of intermediate mesodermal cell fate specification|up-regulation of intermediate mesodermal cell fate specification|up regulation of intermediate mesodermal cell fate specification|stimulation of intermediate mesodermal cell fate specification|activation of intermediate mesodermal cell fate specification													biological_process											owl:Class	
GO:0098956	biolink:NamedThing	intrinsic component of dense core granule membrane	The component of the dense core granule membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to dense core granule membrane													cellular_component											owl:Class	
GO:1902990	biolink:NamedThing	mitotic telomere maintenance via semi-conservative replication	Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.	got7fsn_ti	equal telomere replication involved in mitotic cell cycle|telomeric replication fork progression involved in mitotic cell cycle|telomeric fork progression involved in mitotic cell cycle						jl	2014-05-08T11:13:49Z						biological_process											owl:Class	
GO:2000297	biolink:NamedThing	negative regulation of synapse maturation	Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation.	got7fsn_ti	negative regulation of synaptic maturation						mah	2010-12-23T11:37:31Z						biological_process											owl:Class	
GO:1900833	biolink:NamedThing	D-leucine biosynthetic process	The chemical reactions and pathways resulting in the formation of D-leucine.	got7fsn_ti	D-leucine formation|D-leucine biosynthesis|D-leucine synthesis|D-leucine anabolism						se	2012-06-06T09:37:47Z						biological_process											owl:Class	
GO:0003687	biolink:NamedThing	obsolete DNA replication factor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DNA replication factor				This term was made obsolete because it does not represent a true molecular function.	GO:0006260				True				molecular_function											owl:Class	
GO:0046824	biolink:NamedThing	positive regulation of nucleocytoplasmic transport	Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.	got7fsn_ti	up regulation of nucleocytoplasmic transport|upregulation of nucleocytoplasmic transport|activation of nucleocytoplasmic transport|stimulation of nucleocytoplasmic transport|up-regulation of nucleocytoplasmic transport													biological_process											owl:Class	
GO:2000471	biolink:NamedThing	regulation of hematopoietic stem cell migration	Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.	got7fsn_ti	regulation of hemopoietic stem cell migration						bf	2011-03-09T09:34:08Z						biological_process											owl:Class	
GO:0003437	biolink:NamedThing	regulation of cell communication involved in growth plate cartilage morphogenesis	Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage.	got7fsn_ti							dph	2009-12-22T01:34:24Z						biological_process											owl:Class	
GO:0010679	biolink:NamedThing	obsolete cinnamic acid biosynthetic process involved in salicylic acid metabolism	OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.					True				biological_process											owl:Class	
GO:0006842	biolink:NamedThing	tricarboxylic acid transport	The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0005309	biolink:NamedThing	creatine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).	got7fsn_ti	sodium/chloride-dependent creatine transporter											Reactome:R-HSA-200396		molecular_function											owl:Class	
GO:0050660	biolink:NamedThing	flavin adenine dinucleotide binding	Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.	got7fsn_ti	flavine-adenine dinucleotide binding|FAD or FADH2 binding													molecular_function											owl:Class	
GO:0009210	biolink:NamedThing	pyrimidine ribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside triphosphate degradation|pyrimidine ribonucleoside triphosphate catabolism|pyrimidine ribonucleoside triphosphate breakdown													biological_process											owl:Class	
GO:1903588	biolink:NamedThing	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.	got7fsn_ti	down regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|down-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|downregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|inhibition of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|inhibition of blood vessel endothelial cell proliferation during sprouting angiogenesis|down-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|negative regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|down regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|downregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis						pga	2014-11-04T11:39:39Z						biological_process											owl:Class	
GO:0010949	biolink:NamedThing	negative regulation of intestinal phytosterol absorption	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine.	got7fsn_ti							tb	2009-04-27T11:02:06Z						biological_process											owl:Class	
GO:2001224	biolink:NamedThing	positive regulation of neuron migration	Any process that activates or increases the frequency, rate or extent of neuron migration.	got7fsn_ti	positive regulation of neuronal migration|positive regulation of neuron guidance|positive regulation of neuron chemotaxis						kmv	2011-11-17T10:01:49Z						biological_process											owl:Class	
GO:1990044	biolink:NamedThing	protein localization to lipid droplet	A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet.	got7fsn_ti	protein localisation to adiposome|protein localisation to lipid droplet|protein localisation to lipid particle|protein localisation to lipid body|protein localization to lipid body|protein localization to lipid particle|protein localization to adiposome						sart	2013-02-15T12:40:57Z						biological_process											owl:Class	
GO:2000457	biolink:NamedThing	positive regulation of T-helper 17 cell extravasation	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation.	got7fsn_ti							bf	2011-03-04T10:51:00Z						biological_process											owl:Class	
GO:0075095	biolink:NamedThing	obsolete negative regulation by host of symbiont signal transduction mediated by G-protein beta subunit	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0006746	biolink:NamedThing	FADH2 metabolic process	The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide.	got7fsn_ti	reduced flavin adenine dinucleotide metabolic process|FADH2 metabolism													biological_process											owl:Class	
GO:0010367	biolink:NamedThing	extracellular isoamylase complex	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space.	got7fsn_ti														cellular_component											owl:Class	
GO:0001300	biolink:NamedThing	obsolete chronological cell aging	OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.	got7fsn_ti	chronological cell ageing	https://github.com/geneontology/go-ontology/issues/18632			This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398				True				biological_process											owl:Class	
GO:0030932	biolink:NamedThing	amyloplast ADPG pyrophosphorylase complex	An ADPG pyrophosphorylase complex found in the amyloplast.	got7fsn_ti														cellular_component											owl:Class	
GO:0099101	biolink:NamedThing	G-protein gated potassium channel activity	A potassium channel activity that is gated by binding of a G-protein beta-gamma dimer.	got7fsn_ti														molecular_function											owl:Class	
CL:2000097	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0102072	biolink:NamedThing	obsolete 3-oxo-cis-Delta9-hexadecenoyl-[acp] reductase activity	OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxy cis Delta9-hexadecenoyl-[acp] <=> NADPH + H+ + a 3-oxo-cis-Delta9-hexadecenoyl-[acp].	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21876			This term was obsoleted because it represents a specific substrate, and is beyond the specificity of GO.	GO:0004316				True				molecular_function											owl:Class	
GO:0006053	biolink:NamedThing	N-acetylmannosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.	got7fsn_ti	N-acetylmannosamine breakdown|N-acetylmannosamine degradation|N-acetylmannosamine catabolism													biological_process											owl:Class	
GO:2001023	biolink:NamedThing	regulation of response to drug	Any process that modulates the frequency, rate or extent of response to drug.	got7fsn_ti	regulation of drug resistance|regulation of drug susceptibility/resistance						yaf	2011-08-19T01:47:20Z						biological_process											owl:Class	
GO:1900338	biolink:NamedThing	positive regulation of methane biosynthetic process from carbon monoxide	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide.	got7fsn_ti	up-regulation of methane biosynthetic process from carbon monoxide|activation of methane biosynthetic process from carbon monoxide|upregulation of methane biosynthetic process from carbon monoxide|up regulation of methane biosynthetic process from carbon monoxide						tt	2012-04-06T02:03:33Z						biological_process											owl:Class	
GO:0060227	biolink:NamedThing	Notch signaling pathway involved in camera-type eye photoreceptor fate commitment	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.	got7fsn_ti	Notch signalling pathway involved in camera-type eye photoreceptor fate commitment													biological_process											owl:Class	
GO:0060148	biolink:NamedThing	positive regulation of posttranscriptional gene silencing	Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.	got7fsn_ti														biological_process											owl:Class	
GO:2000713	biolink:NamedThing	negative regulation of maintenance of meiotic sister chromatid cohesion, arms	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.	got7fsn_ti	negative regulation of maintenance of meiotic sister chromatin cohesion along arms|negative regulation of maintenance of sister chromatin cohesion along arms at meiosis I						mah	2011-06-01T12:45:39Z						biological_process											owl:Class	
GO:1902486	biolink:NamedThing	protein localization to growing cell tip	A process in which a protein is transported to, or maintained in, a location within a growing cell tip.	got7fsn_ti	protein localisation in growing cell tip|protein localisation to growing cell tip|protein localization in growing cell tip						mah	2013-11-12T16:38:13Z						biological_process											owl:Class	
GO:0003397	biolink:NamedThing	neuron migration involved in amphid sensory organ dendrite retrograde extension	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ.	got7fsn_ti							dph	2009-12-09T09:52:18Z						biological_process											owl:Class	
GO:0106191	biolink:NamedThing	obsolete translocase activity acting on inogranic cations linked to oxidoreductase reactions	OBSOLETE. Catalysis of the translocation of inorganic cations linked to oxidoreductase reactions.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T16:50:07Z		True		EC:7.2.1.-		molecular_function											owl:Class	
GO:0006142	biolink:NamedThing	regulation of pyrimidine nucleobase metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.	got7fsn_ti	regulation of pyrimidine base metabolism|regulation of pyrimidine base metabolic process													biological_process											owl:Class	
GO:1900073	biolink:NamedThing	regulation of neuromuscular synaptic transmission	Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.	got7fsn_ti							kmv	2012-01-26T10:14:10Z						biological_process											owl:Class	
GO:0090679	biolink:NamedThing	cell differentiation involved in phenotypic switching	A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.	got7fsn_ti							tb	2016-04-28T17:32:40Z						biological_process											owl:Class	
GO:0000219	biolink:NamedThing	obsolete vacuolar hydrogen-transporting ATPase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	vacuolar hydrogen-transporting ATPase|V-ATPase				This term was made obsolete because more specific terms were created.	GO:0016469				True				cellular_component											owl:Class	
GO:0033547	biolink:NamedThing	obsolete myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate	OBSOLETE. The chemical reactions and pathways resulting in the formation of 1D myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is successively phosphorylated to yield inositol hexakisphosphate.	got7fsn_ti	phytate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate formation, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate synthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|phytate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate anabolism, via direct phosphorylation of inositol 1,4,5-trisphosphate				This term was made obsolete because its only cross-reference points to a MetaCyc entry (PWY-4541) that was deleted from the MetaCyc database.					True		MetaCyc:PWY-4541		biological_process											owl:Class	
GO:1902062	biolink:NamedThing	betaine aldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of betaine aldehyde.	got7fsn_ti	betaine aldehyde degradation|betaine aldehyde breakdown|betaine aldehyde catabolism						di	2013-04-16T12:07:12Z						biological_process											owl:Class	
GO:1905900	biolink:NamedThing	negative regulation of smooth muscle tissue development	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development.	got7fsn_ti	downregulation of smooth muscle tissue development|down regulation of smooth muscle tissue development|down-regulation of smooth muscle tissue development|inhibition of smooth muscle tissue development						bhm	2017-02-01T14:31:24Z						biological_process											owl:Class	
GO:0042422	biolink:NamedThing	norepinephrine catabolic process	The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.	got7fsn_ti	norepinephrine catabolism|levarterenol catabolism|norepinephrine degradation|noradrenaline catabolism|noradrenaline catabolic process|norepinephrine breakdown|levarterenol catabolic process											Wikipedia:Norepinephrine#Degradation		biological_process											owl:Class	
GO:1903221	biolink:NamedThing	regulation of mitotic recombination involved in replication fork processing	Any process that modulates the frequency, rate or extent of mitotic recombination involved in replication fork processing. Regulation of mitotic recombination contributes to replication fork processing by preventing recombination between inappropriate homologous sequences.	got7fsn_ti	regulation of mitotic recombination involved in collapsed replication fork processing|regulation of mitotic recombination involved in replication restart|regulation of mitotic recombination involved in replication fork restart|regulation of mitotic recombination involved in recovery from replication fork stalling|prevention of genomic instability induced by DNA replication fork arrest|regulation of mitotic recombination involved in recovery from replication fork arrest						mah	2014-07-24T13:30:21Z						biological_process											owl:Class	
GO:1990693	biolink:NamedThing	intrinsic component of Golgi cis cisterna membrane	The component of the Golgi cis cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic component of cis-Golgi cisterna membrane						bhm	2015-03-12T10:24:07Z						cellular_component											owl:Class	
GO:1905311	biolink:NamedThing	negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.	got7fsn_ti	downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis|down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis						rl	2016-07-11T17:34:35Z						biological_process											owl:Class	
GO:0043443	biolink:NamedThing	acetone metabolic process	The chemical reactions and pathways involving acetone, propan-2-one.	got7fsn_ti	2-propanone metabolic process|dimethyl ketone metabolic process|propan-2-one metabolic process|propan-2-one metabolism|dimethyl ketone metabolism|acetone metabolism|2-propanone metabolism													biological_process											owl:Class	
GO:1901567	biolink:NamedThing	fatty acid derivative binding	Binding to fatty acid derivative.	got7fsn_ti							pr	2012-11-04T17:13:28Z						molecular_function											owl:Class	
GO:0001686	biolink:NamedThing	obsolete axonemal dynein light chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	axonemal dynein light chain			GO:0005858	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:0031280	biolink:NamedThing	negative regulation of cyclase activity	Any process that stops or reduces the activity of a cyclase.	got7fsn_ti	down regulation of cyclase activity|inhibition of cyclase activity|down-regulation of cyclase activity|downregulation of cyclase activity													biological_process											owl:Class	
GO:0033624	biolink:NamedThing	negative regulation of integrin activation	Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation.	got7fsn_ti	negative regulation of integrin complex activation													biological_process											owl:Class	
GO:2000434	biolink:NamedThing	regulation of protein neddylation	Any process that modulates the frequency, rate or extent of protein neddylation.	got7fsn_ti	regulation of RUB1-protein conjugation						vw	2011-03-03T02:05:22Z						biological_process											owl:Class	
GO:0090336	biolink:NamedThing	positive regulation of brown fat cell differentiation	Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.	got7fsn_ti							tb	2010-06-01T03:19:26Z						biological_process											owl:Class	
GO:0033265	biolink:NamedThing	choline binding	Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.	got7fsn_ti														molecular_function											owl:Class	
GO:0032930	biolink:NamedThing	positive regulation of superoxide anion generation	Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.	got7fsn_ti	upregulation of superoxide release|activation of superoxide release|up regulation of superoxide release|positive regulation of superoxide release|up-regulation of superoxide release|stimulation of superoxide release													biological_process											owl:Class	
GO:2000727	biolink:NamedThing	positive regulation of cardiac muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.	got7fsn_ti	positive regulation of heart muscle cell differentiation|positive regulation of cardiomyocyte differentiation						vk	2011-06-08T10:51:15Z						biological_process											owl:Class	
GO:1905796	biolink:NamedThing	regulation of intraciliary anterograde transport	Any process that modulates the frequency, rate or extent of intraciliary anterograde transport.	got7fsn_ti	regulation of intraflagellar anterograde transport						hbye	2017-01-11T12:55:35Z						biological_process											owl:Class	
GO:0035562	biolink:NamedThing	negative regulation of chromatin binding	Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	got7fsn_ti							bf	2010-05-19T10:29:06Z						biological_process											owl:Class	
GO:1904641	biolink:NamedThing	response to dinitrophenol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.	got7fsn_ti	response to dinitrophenols						sl	2015-08-31T20:13:12Z						biological_process											owl:Class	
GO:0110041	biolink:NamedThing	regulation of pharynx morphogenesis	Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.	got7fsn_ti							kmv	2017-07-24T21:00:20Z						biological_process											owl:Class	
GO:0005695	biolink:NamedThing	obsolete chromatid	OBSOLETE. One of the two daughter strands of a duplicated chromosome that become apparent between early prophase and metaphase in mitosis and between diplotene and second metaphase in meiosis.	got7fsn_ti	chromatid				This term was made obsolete because it is not a unique subcellular component, i.e. the difference between this term and 'chromosome' is based on temporal and process distinctions.	GO:0000793|GO:0005694|GO:0000794				True				cellular_component											owl:Class	
GO:0048714	biolink:NamedThing	positive regulation of oligodendrocyte differentiation	Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.	got7fsn_ti	up regulation of oligodendrocyte differentiation|upregulation of oligodendrocyte differentiation|stimulation of oligodendrocyte differentiation|up-regulation of oligodendrocyte differentiation|activation of oligodendrocyte differentiation													biological_process											owl:Class	
GO:0003394	biolink:NamedThing	cell adhesion involved in dendrite retrograde extension	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite.	got7fsn_ti							dph	2009-12-09T09:42:09Z						biological_process											owl:Class	
GO:0031926	biolink:NamedThing	pyridoxal phosphate transmembrane transporter activity	Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.	got7fsn_ti														molecular_function											owl:Class	
GO:0070282	biolink:NamedThing	pyridoxine binding	Binding to pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.	got7fsn_ti														molecular_function											owl:Class	
GO:0001810	biolink:NamedThing	regulation of type I hypersensitivity	Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response.	got7fsn_ti														biological_process											owl:Class	
GO:0043520	biolink:NamedThing	regulation of myosin II filament assembly	Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0035884	biolink:NamedThing	arabinan biosynthetic process	The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues.	got7fsn_ti							bf	2011-06-08T11:01:14Z						biological_process											owl:Class	
GO:1901053	biolink:NamedThing	sarcosine catabolic process	The chemical reactions and pathways resulting in the breakdown of sarcosine.	got7fsn_ti	sarcosine degradation|sarcosine breakdown|sarcosine catabolism						yaf	2012-06-28T04:52:29Z						biological_process											owl:Class	
GO:0045758	biolink:NamedThing	obsolete positive regulation of actin polymerization and/or depolymerization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of actin polymerization and/or depolymerization.	got7fsn_ti	positive regulation of actin polymerization and/or depolymerization				This term was made obsolete because it has been split.	GO:0030838|GO:0030836				True				biological_process											owl:Class	
GO:0006251	biolink:NamedThing	dCDP catabolic process	The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate.	got7fsn_ti	dCDP degradation|dCDP catabolism|dCDP breakdown													biological_process											owl:Class	
GO:0015333	biolink:NamedThing	peptide:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement.	got7fsn_ti	peptide:hydrogen symporter activity											RHEA:37047|Reactome:R-HSA-428007|Reactome:R-HSA-427998		molecular_function											owl:Class	
GO:0034179	biolink:NamedThing	regulation of toll-like receptor 13 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 13 signalling pathway|regulation of TLR13 signaling pathway													biological_process											owl:Class	
GO:1905015	biolink:NamedThing	regulation of isoleucine-tRNA ligase activity	Any process that modulates the frequency, rate or extent of isoleucine-tRNA ligase activity.	got7fsn_ti	regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|regulation of isoleucyl-tRNA synthetase activity|regulation of isoleucine-tRNA synthetase activity|regulation of isoleucyl-transfer RNA synthetase activity|regulation of isoleucine-transfer RNA ligase activity|regulation of isoleucine translase activity|regulation of isoleucyl-transfer ribonucleate synthetase activity						sl	2016-03-03T19:00:48Z						biological_process											owl:Class	
GO:0071653	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 1 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.	got7fsn_ti	negative regulation of T cell activation 3 production|negative regulation of TCA-3 production|negative regulation of CCL1 production						mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:0010105	biolink:NamedThing	negative regulation of ethylene-activated signaling pathway	Any process that stops or prevents ethylene (ethene) signal transduction.	got7fsn_ti	negative regulation of ethylene mediated signalling pathway|down regulation of ethylene mediated signaling pathway|negative regulation of ethylene mediated signaling pathway|downregulation of ethylene mediated signaling pathway|inhibition of ethylene mediated signaling pathway|down-regulation of ethylene mediated signaling pathway|negative regulation of ethene mediated signalling pathway|negative regulation of ethene mediated signaling pathway													biological_process											owl:Class	
GO:0035386	biolink:NamedThing	regulation of Roundabout signaling pathway	Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway.	got7fsn_ti	regulation of Roundabout signalling pathway						bf	2010-03-18T02:39:24Z						biological_process											owl:Class	
GO:2001049	biolink:NamedThing	regulation of tendon cell differentiation	Any process that modulates the frequency, rate or extent of tendon cell differentiation.	got7fsn_ti	regulation of tenocyte differentiation|regulation of muscle attachment cell differentiation						yaf	2011-09-01T09:20:32Z						biological_process											owl:Class	
GO:1901256	biolink:NamedThing	regulation of macrophage colony-stimulating factor production	Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production.	got7fsn_ti	regulation of M-CSF production						vk	2012-08-10T08:28:08Z						biological_process											owl:Class	
GO:0010194	biolink:NamedThing	obsolete microRNA metabolic process	OBSOLETE. The chemical reactions and pathways involving microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity.	got7fsn_ti	microRNA metabolic process			GO:0035196	This term was made obsolete because it implies further processing of an end product rather than its production.					True				biological_process											owl:Class	
GO:0060622	biolink:NamedThing	regulation of ascospore wall beta-glucan biosynthetic process	Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.	got7fsn_ti							dph	2009-05-18T02:01:26Z						biological_process											owl:Class	
GO:1903342	biolink:NamedThing	negative regulation of meiotic DNA double-strand break formation	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation.	got7fsn_ti	downregulation of meiotic DNA double-strand break formation|inhibition of meiotic DNA double-strand break formation|down-regulation of meiotic DNA double-strand break formation|down regulation of meiotic DNA double-strand break formation						mcc	2014-08-18T21:32:03Z						biological_process											owl:Class	
GO:1905316	biolink:NamedThing	superior endocardial cushion morphogenesis	The developmental process by which a superior endocardial cushion is generated and organized.	got7fsn_ti	dorsal endocardial cushion morphogenesis						rl	2016-07-12T14:08:35Z						biological_process											owl:Class	
GO:0019694	biolink:NamedThing	alkanesulfonate metabolic process	The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.	got7fsn_ti	alkanesulfonate metabolism|alkanesulphonate metabolic process|alkanesulphonate metabolism											MetaCyc:ALKANEMONOX-PWY		biological_process											owl:Class	
GO:1904737	biolink:NamedThing	positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.	got7fsn_ti	activation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|up regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|upregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|up-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase						lb	2015-10-15T08:15:03Z						biological_process											owl:Class	
GO:0003273	biolink:NamedThing	cell migration involved in endocardial cushion formation	The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	got7fsn_ti							dph	2009-10-20T09:08:44Z						biological_process											owl:Class	
GO:0005015	biolink:NamedThing	obsolete neurotrophin TRKB receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	neurotrophin TRKB receptor activity				This term was made obsolete because it represents a gene product.	GO:0004714|GO:0048403|GO:0043121|GO:0007165				True				molecular_function											owl:Class	
GO:0090314	biolink:NamedThing	positive regulation of protein targeting to membrane	Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.	got7fsn_ti							tb	2010-04-16T03:42:22Z						biological_process											owl:Class	
GO:0052264	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000102	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903897	biolink:NamedThing	regulation of PERK-mediated unfolded protein response	Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response.	got7fsn_ti	regulation of PERK signal transduction pathway|regulation of UPR signaling by PERK stress sensor|regulation of endoplasmic reticulum unfolded protein response; PERK signaling|regulation of EIF2AK3-mediated unfolded protein response|regulation of PKR-like ER kinase signal transduction|regulation of PERK signaling in response to endoplasmic reticulum stress|regulation of PERK branch of UPR						bf	2015-02-09T10:18:14Z						biological_process											owl:Class	
GO:0009334	biolink:NamedThing	3-phenylpropionate dioxygenase complex	Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol).	got7fsn_ti					See also the molecular function term '3-phenylpropionate dioxygenase activity ; GO:0008695'.							MetaCyc:HCAMULTI-CPLX		cellular_component											owl:Class	
GO:0035364	biolink:NamedThing	thymine transport	The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	thymine transmembrane transport|5-methyluracil transport						bf	2010-03-11T10:20:24Z						biological_process											owl:Class	
GO:0002635	biolink:NamedThing	negative regulation of germinal center formation	Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.	got7fsn_ti	down regulation of germinal center formation|inhibition of germinal center formation|down-regulation of germinal center formation|downregulation of germinal center formation													biological_process											owl:Class	
GO:0010981	biolink:NamedThing	regulation of cell wall macromolecule metabolic process	Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	got7fsn_ti							tb	2009-06-01T11:55:35Z						biological_process											owl:Class	
GO:0010527	biolink:NamedThing	positive regulation of transposition, RNA-mediated	Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.	got7fsn_ti														biological_process											owl:Class	
GO:0002826	biolink:NamedThing	negative regulation of T-helper 1 type immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response.	got7fsn_ti	down regulation of T-helper 1 type immune response|down-regulation of T-helper 1 type immune response|downregulation of T-helper 1 type immune response|inhibition of T-helper 1 type immune response													biological_process											owl:Class	
GO:0005541	biolink:NamedThing	obsolete acyl-CoA or acyl binding	OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid.	got7fsn_ti	acyl-CoA or acyl binding				This term was made obsolete because it was replaced by more appropriate terms.	GO:0000062|GO:0000035				True				molecular_function											owl:Class	
GO:0052198	biolink:NamedThing	obsolete modulation of peptidase activity in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation of protease activity in other organism during symbiotic interaction|modulation of protease activity in other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0072750	biolink:NamedThing	cellular response to leptomycin B	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.	got7fsn_ti							mah	2012-09-10T14:07:32Z						biological_process											owl:Class	
GO:0019244	biolink:NamedThing	lactate biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate.	got7fsn_ti	lactate formation from pyruvate|lactate anabolism from pyruvate|pyruvate fermentation to lactate|lactate synthesis from pyruvate											Reactome:R-HSA-71849.1		biological_process											owl:Class	
GO:0072292	biolink:NamedThing	epithelial cell migration involved in metanephric proximal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis.	got7fsn_ti							mah	2010-04-09T03:54:28Z						biological_process											owl:Class	
GO:0005562	biolink:NamedThing	obsolete RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	RNA				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
CHEBI:30911	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904155	biolink:NamedThing	DN2 thymocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-.	got7fsn_ti							dph	2015-04-15T12:52:53Z						biological_process											owl:Class	
GO:0090146	biolink:NamedThing	obsolete establishment of mitochondrion localization involved in mitochondrial fission	OBSOLETE. The directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.	got7fsn_ti	establishment of mitochondrion localisation involved in mitochondrial fission|mitochondrial localization involved in mitochondrial fission	https://github.com/geneontology/go-ontology/issues/18417			This term was obsoleted because it represented a phenotype.	GO:0000002|GO:0000266	tb	2009-12-08T02:53:15Z		True				biological_process											owl:Class	
GO:0070596	biolink:NamedThing	(1->3)-alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.	got7fsn_ti	1,3-alpha-glucan biosynthetic process|alpha-1,3 glucan anabolism|1,3-alpha-glucan formation|1,3-alpha-glucan synthesis|1,3-alpha-glucan biosynthesis|alpha-1,3 glucan biosynthetic process|alpha-1,3 glucan formation|alpha-1,3 glucan biosynthesis|alpha-1,3 glucan synthesis|1,3-alpha-glucan anabolism						mah	2009-04-28T03:39:24Z						biological_process											owl:Class	
GO:1901672	biolink:NamedThing	positive regulation of systemic acquired resistance	Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.	got7fsn_ti	up-regulation of salicylic acid-dependent systemic resistance|upregulation of salicylic acid-dependent systemic resistance|positive regulation of salicylic acid-dependent systemic resistance|activation of salicylic acid-dependent systemic resistance|activation of systemic acquired resistance|up-regulation of systemic acquired resistance|up regulation of systemic acquired resistance|up regulation of salicylic acid-dependent systemic resistance|upregulation of systemic acquired resistance						tb	2012-11-21T22:03:58Z						biological_process											owl:Class	
GO:0018983	biolink:NamedThing	Z-phenylacetaldoxime metabolic process	The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants.	got7fsn_ti	Z-phenylacetaldoxime metabolism											UM-BBD_pathwayID:pao		biological_process											owl:Class	
GO:0046711	biolink:NamedThing	GDP biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.	got7fsn_ti	GDP formation|GDP synthesis|GDP biosynthesis|GDP anabolism													biological_process											owl:Class	
GO:0036146	biolink:NamedThing	cellular response to mycotoxin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.	got7fsn_ti							bf	2012-03-12T11:08:22Z						biological_process											owl:Class	
GO:0070981	biolink:NamedThing	L-asparagine biosynthetic process	The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.	got7fsn_ti	L-asparagine formation|L-asparagine biosynthesis|L-asparagine anabolism|L-asparagine synthesis						mah	2009-10-27T12:59:42Z						biological_process											owl:Class	
GO:1902163	biolink:NamedThing	negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.	got7fsn_ti	inhibition of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|down regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator						lb	2013-05-22T12:39:23Z						biological_process											owl:Class	
GO:0009984	biolink:NamedThing	obsolete adenylate forming enzyme activity	OBSOLETE. Catalysis of the reaction: substrate + ATP = substrate-AMP + diphosphate.	got7fsn_ti	adenylate forming enzyme activity				This term was made obsolete because it does not refer to a specific reaction but rather to a process which results in the formation of AMP.	GO:0046033				True				molecular_function											owl:Class	
GO:1903312	biolink:NamedThing	negative regulation of mRNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.	got7fsn_ti	down regulation of mRNA metabolic process|down-regulation of mRNA metabolic process|down-regulation of mRNA metabolism|inhibition of mRNA metabolism|downregulation of mRNA metabolism|down regulation of mRNA metabolism|inhibition of mRNA metabolic process|negative regulation of mRNA metabolism|downregulation of mRNA metabolic process						vw	2014-08-18T11:52:34Z						biological_process											owl:Class	
GO:0008597	biolink:NamedThing	calcium-dependent protein serine/threonine phosphatase regulator activity	Binds to and modulates of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase.	got7fsn_ti	calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity											Reactome:R-HSA-139906		molecular_function											owl:Class	
GO:0061881	biolink:NamedThing	positive regulation of anterograde axonal transport of mitochondrion	Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.	got7fsn_ti	positive regulation of anterograde axon transport of mitochondria						dph	2017-05-30T14:21:08Z						biological_process											owl:Class	
GO:2000900	biolink:NamedThing	cyclodextrin metabolic process	The chemical reactions and pathways involving a cyclodextrin.	got7fsn_ti	cyclodextrin metabolism						jl	2011-07-28T03:19:11Z						biological_process											owl:Class	
GO:0071213	biolink:NamedThing	cellular response to 1-aminocyclopropane-1-carboxylic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.	got7fsn_ti							mah	2009-12-03T12:10:11Z						biological_process											owl:Class	
GO:0014050	biolink:NamedThing	negative regulation of glutamate secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.	got7fsn_ti	down regulation of glutamate secretion|downregulation of glutamate secretion|down-regulation of glutamate secretion|inhibition of glutamate secretion													biological_process											owl:Class	
GO:0009322	biolink:NamedThing	trimethylamine-N-oxide reductase complex	An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine.	got7fsn_ti														cellular_component											owl:Class	
GO:0060353	biolink:NamedThing	regulation of cell adhesion molecule production	Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0046713	biolink:NamedThing	borate transport	The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.	got7fsn_ti	boron transport													biological_process											owl:Class	
GO:0014884	biolink:NamedThing	detection of muscle inactivity involved in regulation of muscle adaptation	The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.	got7fsn_ti														biological_process											owl:Class	
GO:0005332	biolink:NamedThing	gamma-aminobutyric acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in).	got7fsn_ti	4-aminobutanoate:sodium symporter activity|sodium/chloride-dependent GABA transporter activity|4-aminobutyrate:sodium symporter activity|GABA:sodium symporter activity|betaine/GABA:sodium symporter activity				See also the molecular function term 'neurotransmitter:sodium symporter activity ; GO:0005328'.							Reactome:R-HSA-444007		molecular_function											owl:Class	
GO:0016105	biolink:NamedThing	triterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units.	got7fsn_ti	triterpene catabolism|triterpene catabolic process|triterpenoid catabolism|triterpenoid degradation|triterpenoid breakdown													biological_process											owl:Class	
GO:1904014	biolink:NamedThing	response to serotonin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.	got7fsn_ti							sl	2015-03-06T19:33:54Z						biological_process											owl:Class	
CL:0010006	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901281	biolink:NamedThing	fructoselysine catabolic process	The chemical reactions and pathways resulting in the breakdown of fructoselysine.	got7fsn_ti	fructosyllysine catabolic process|fructosyllysine degradation|fructosyllysine catabolism|fructosyllysine breakdown						yaf	2012-08-17T15:04:43Z						biological_process											owl:Class	
GO:1904984	biolink:NamedThing	regulation of quinolinate biosynthetic process	Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process.	got7fsn_ti	regulation of quinolinate anabolism|regulation of quinolinate biosynthesis|regulation of quinolinate formation|regulation of quinolinate synthesis						bf	2016-02-29T15:54:12Z						biological_process											owl:Class	
GO:1904226	biolink:NamedThing	regulation of glycogen synthase activity, transferring glucose-1-phosphate	Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.	got7fsn_ti							rl	2015-05-15T09:23:08Z						biological_process											owl:Class	
GO:1904345	biolink:NamedThing	negative regulation of gastric mucosal blood circulation	Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation.	got7fsn_ti	inhibition of gastric mucosal blood circulation|down-regulation of stomach mucosal blood circulation|inhibition of stomach mucosal blood circulation|down regulation of stomach mucosal blood circulation|downregulation of gastric mucosal blood circulation|negative regulation of stomach mucosal blood circulation|down-regulation of gastric mucosal blood circulation|down regulation of gastric mucosal blood circulation|downregulation of stomach mucosal blood circulation						sl	2015-06-11T21:20:44Z						biological_process											owl:Class	
GO:1901921	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex	Any phosphorylation of RNA polymerase II C-terminal domain that is involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex.	got7fsn_ti	CTD domain phosphorylation of RNA polymerase II involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex						rb	2013-02-15T19:09:31Z						biological_process											owl:Class	
GO:1904962	biolink:NamedThing	plastid to vacuole vesicle-mediated transport	The vesicle-mediated and directed movement of substances from plastid to vacuole.	got7fsn_ti	plastid to vacuolar carboxypeptidase Y vesicle-mediated transport						tb	2016-02-10T00:14:48Z						biological_process											owl:Class	
GO:1903633	biolink:NamedThing	regulation of leucine-tRNA ligase activity	Any process that modulates the frequency, rate or extent of leucine-tRNA ligase activity.	got7fsn_ti	regulation of leucyl-transfer ribonucleate synthetase activity|regulation of L-leucine:tRNALeu ligase (AMP-forming)|regulation of leucine translase activity|regulation of leucyl-tRNA synthetase activity|regulation of leucine-tRNA synthetase activity|regulation of leucyl-transfer RNA synthetase activity|regulation of leucyl-transfer ribonucleic acid synthetase activity						sl	2014-11-20T00:24:48Z						biological_process											owl:Class	
GO:0019845	biolink:NamedThing	obsolete exotoxin activity	OBSOLETE. The function of a toxin formed by a microorganism and secreted into the surrounding medium.	got7fsn_ti	exotoxin activity				This term was made obsolete because it represents a class of gene products.	GO:0090729|GO:0005576				True				molecular_function											owl:Class	
GO:0010538	biolink:NamedThing	obsolete Hsp27 protein regulator activity	OBSOLETE. Modulates the activity of the Hsp27 molecular chaperone.	got7fsn_ti	Hsp27 protein regulator activity			GO:0051008	This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp27 protein activity'.	GO:0051082|GO:0051787|GO:0006457				True				molecular_function											owl:Class	
GO:0016808	biolink:NamedThing	obsolete proprotein convertase activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	proprotein convertase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1904771	biolink:NamedThing	obsolete cellular response to doxorubicin	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-10-28T20:48:30Z		True				biological_process											owl:Class	
GO:0005027	biolink:NamedThing	obsolete NGF/TNF (6 C-domain) receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	NGF/TNF (6 C-domain) receptor activity				This term was made obsolete because it represents a protein family rather than a molecular function.	GO:0005031				True				molecular_function											owl:Class	
GO:0039607	biolink:NamedThing	obsolete proteolysis by virus of host translation initiation factor	OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of a host translation initiation factor by cleavage of its peptide bonds.	got7fsn_ti	proteolytic cleavage by virus of host translation initiation factor|suppression by virus of host translation initiation factor activity by proteolysis|cleavage of host translation initiation factor by viral protease|cleavage of host translation initiation factor by virus				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-07-05T04:46:21Z		True				biological_process											owl:Class	
GO:0016304	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase activity, class I	OBSOLETE. A heterodimeric phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol, phosphatidylinositol-4-phosphate or phosphatidylinositol-4,5-bisphosphate. Also possesses intrinsic protein kinase activity.	got7fsn_ti	phosphatidylinositol 3-kinase activity, class I				This term was made obsolete because it represents a class of gene products.	GO:0016303|GO:0046934|GO:0035005				True				molecular_function											owl:Class	
GO:1904424	biolink:NamedThing	regulation of GTP binding	Any process that modulates the frequency, rate or extent of GTP binding.	got7fsn_ti							sl	2015-07-02T20:34:44Z						biological_process											owl:Class	
GO:1905511	biolink:NamedThing	positive regulation of myosin II filament assembly	Any process that activates or increases the frequency, rate or extent of myosin II filament assembly.	got7fsn_ti	up regulation of myosin II polymerization|upregulation of myosin II filament assembly|positive regulation of myosin II polymerization|upregulation of myosin II polymerization|up-regulation of myosin II polymerization|up-regulation of myosin II filament assembly|activation of myosin II polymerization|up regulation of myosin II filament assembly|activation of myosin II filament assembly				positive regulation / down regulation of the formation of a bipolar filament composed of myosin II molecules		pf	2016-09-28T13:48:03Z						biological_process											owl:Class	
GO:0007515	biolink:NamedThing	obsolete lymph gland development	OBSOLETE. The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is a small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells. Lymph glands are located along the lymphatic system.	got7fsn_ti	lymph gland development				This term was made obsolete because it was wrongly defined.	GO:0048542|GO:0048535				True				biological_process											owl:Class	
GO:1901997	biolink:NamedThing	negative regulation of indoleacetic acid biosynthetic process via tryptophan	Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.	got7fsn_ti	inhibition of indoleacetic acid formation via tryptophan|down-regulation of indoleacetic acid synthesis via tryptophan|inhibition of indoleacetic acid anabolism via tryptophan|down-regulation of indoleacetic acid anabolism via tryptophan|inhibition of indoleacetic acid biosynthetic process via tryptophan|down regulation of indoleacetic acid biosynthetic process via tryptophan|inhibition of indoleacetic acid synthesis via tryptophan|down regulation of indoleacetic acid anabolism via tryptophan|negative regulation of IAA biosynthetic process via tryptophan|negative regulation of indoleacetic acid synthesis via tryptophan|downregulation of indoleacetic acid formation via tryptophan|downregulation of indoleacetic acid anabolism via tryptophan|downregulation of indoleacetic acid biosynthetic process via tryptophan|negative regulation of indoleacetic acid formation via tryptophan|downregulation of indoleacetic acid synthesis via tryptophan|down-regulation of indoleacetic acid biosynthetic process via tryptophan|down regulation of IAA biosynthetic process via tryptophan|down regulation of indoleacetic acid synthesis via tryptophan|negative regulation of indoleacetic acid anabolism via tryptophan|inhibition of IAA biosynthetic process via tryptophan|down-regulation of indoleacetic acid formation via tryptophan|down-regulation of IAA biosynthetic process via tryptophan|down regulation of indoleacetic acid formation via tryptophan|downregulation of IAA biosynthetic process via tryptophan						tb	2013-03-19T19:14:13Z						biological_process											owl:Class	
GO:0006154	biolink:NamedThing	adenosine catabolic process	The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.	got7fsn_ti	adenosine catabolism|adenosine phosphorolysis|adenosine breakdown|adenosine degradation										GO:0006156			biological_process											owl:Class	
UBERON:0002540	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21437	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033595	biolink:NamedThing	response to genistein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0010781	biolink:NamedThing	meiotic DNA double-strand break formation involved in meiotic gene conversion	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.	got7fsn_ti														biological_process											owl:Class	
GO:1903744	biolink:NamedThing	positive regulation of anterograde synaptic vesicle transport	Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport.	got7fsn_ti	up regulation of anterograde synaptic vesicle transport|upregulation of anterograde synaptic vesicle transport|activation of anterograde synaptic vesicle transport|up-regulation of anterograde synaptic vesicle transport						kmv	2014-12-12T16:28:46Z						biological_process											owl:Class	
GO:0070028	biolink:NamedThing	obsolete regulation of transcription by carbon monoxide	OBSOLETE. Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription.	got7fsn_ti	regulation of transcription by CO				This term was obsoleted because it represents a GO-CAM model.	GO:0006357				True				biological_process											owl:Class	
GO:1900345	biolink:NamedThing	regulation of methane biosynthetic process from methanethiol	Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol.	got7fsn_ti							tt	2012-04-06T02:09:49Z						biological_process											owl:Class	
GO:0062070	biolink:NamedThing	SAGA complex binding	Binding to a SAGA complex.	got7fsn_ti							dph	2018-08-31T14:13:36Z						molecular_function											owl:Class	
GO:1901246	biolink:NamedThing	regulation of lung ciliated cell differentiation	Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation.	got7fsn_ti							vk	2012-08-08T08:58:34Z						biological_process											owl:Class	
GO:0033245	biolink:NamedThing	negative regulation of penicillin metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti	negative regulation of penicillin metabolism													biological_process											owl:Class	
GO:1901749	biolink:NamedThing	leukotriene D4 catabolic process	The chemical reactions and pathways resulting in the breakdown of leukotriene D4.	got7fsn_ti	leukotriene D4 breakdown|leukotriene D4 degradation|leukotriene D4 catabolism						yaf	2013-01-14T10:56:17Z						biological_process											owl:Class	
GO:0032211	biolink:NamedThing	negative regulation of telomere maintenance via telomerase	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.	got7fsn_ti	downregulation of telomere maintenance via telomerase activity|down-regulation of telomere maintenance via telomerase activity|down regulation of telomere maintenance via telomerase activity|inhibition of telomere maintenance via telomerase													biological_process											owl:Class	
GO:0009696	biolink:NamedThing	salicylic acid metabolic process	The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.	got7fsn_ti	salicylic acid metabolism													biological_process											owl:Class	
GO:0033527	biolink:NamedThing	tetrapyrrole biosynthetic process from glycine and succinyl-CoA	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA.	got7fsn_ti	tetrapyrrole synthesis from glycine and succinyl-CoA|tetrapyrrole anabolism from glycine and succinyl-CoA|tetrapyrrole biosynthesis from glycine and succinyl-CoA|tetrapyrrole formation from glycine and succinyl-CoA											MetaCyc:PWY-5189		biological_process											owl:Class	
GO:0005481	biolink:NamedThing	obsolete vesicle fusion	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	vesicle fusion				This term was made obsolete because it represents a biological process and not a molecular function.	GO:0006906|GO:0019817|GO:0007086|GO:0016192|GO:0016189				True				molecular_function											owl:Class	
GO:0061854	biolink:NamedThing	positive regulation of neuroblast migration	Any process that activates or increases the frequency, rate or extent of neuroblast migration.	got7fsn_ti							dph	2017-03-08T18:22:30Z						biological_process											owl:Class	
GO:0002858	biolink:NamedThing	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.	got7fsn_ti														biological_process											owl:Class	
GO:0018948	biolink:NamedThing	xylene metabolic process	The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.	got7fsn_ti	xylene metabolism													biological_process											owl:Class	
GO:0032804	biolink:NamedThing	negative regulation of low-density lipoprotein particle receptor catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors.	got7fsn_ti	down regulation of low-density lipoprotein receptor catabolic process|down-regulation of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor catabolism|negative regulation of low-density lipoprotein receptor breakdown|downregulation of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor degradation|inhibition of low-density lipoprotein receptor catabolic process													biological_process											owl:Class	
GO:0030826	biolink:NamedThing	obsolete regulation of cGMP biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.	got7fsn_ti	regulation of cGMP formation|regulation of cGMP biosynthesis|regulation of cGMP synthesis|regulation of cGMP anabolism				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
CL:0000598	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901299	biolink:NamedThing	negative regulation of hydrogen peroxide-mediated programmed cell death	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.	got7fsn_ti	downregulation of hydrogen peroxide-mediated programmed cell death|down-regulation of hydrogen peroxide-mediated programmed cell death|inhibition of hydrogen peroxide-mediated programmed cell death|down regulation of hydrogen peroxide-mediated programmed cell death						vk	2012-08-21T09:45:21Z						biological_process											owl:Class	
GO:1905889	biolink:NamedThing	positive regulation of cellular response to very-low-density lipoprotein particle stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.	got7fsn_ti	upregulation of cellular response to very-low-density lipoprotein particle stimulus|upregulation of cellular response to VLDL particle stimulus|up regulation of cellular response to VLDL particle stimulus|activation of cellular response to VLDL particle stimulus|positive regulation of cellular response to VLDL particle stimulus|activation of cellular response to very-low-density lipoprotein particle stimulus|up regulation of cellular response to very-low-density lipoprotein particle stimulus|up-regulation of cellular response to VLDL particle stimulus|up-regulation of cellular response to very-low-density lipoprotein particle stimulus						bc	2017-02-01T10:09:34Z						biological_process											owl:Class	
GO:2001057	biolink:NamedThing	reactive nitrogen species metabolic process	The chemical reactions and pathways involving a reactive nitrogen species.	got7fsn_ti	RNS metabolism|reactive nitrogen species metabolism|RNS metabolic process						jl	2011-09-09T01:29:13Z						biological_process											owl:Class	
GO:1901686	biolink:NamedThing	glutathione derivative catabolic process	The chemical reactions and pathways resulting in the breakdown of glutathione derivative.	got7fsn_ti	glutathione derivative catabolism|glutathione derivative degradation|glutathione derivative breakdown						pr	2012-12-05T11:57:16Z						biological_process											owl:Class	
GO:0075191	biolink:NamedThing	obsolete autophagy of host cells on or near symbiont surface	OBSOLETE. The process in which the host cells digest parts of their own cytoplasm, occurring when the host is on or near its symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that this term did not represent any specific host/symbiont process.					True				biological_process											owl:Class	
GO:1904686	biolink:NamedThing	regulation of mitotic spindle disassembly	Any process that modulates the frequency, rate or extent of mitotic spindle disassembly.	got7fsn_ti	regulation of mitotic spindle degradation|regulation of spindle breakdown during mitosis|regulation of spindle degradation during mitosis|regulation of mitotic spindle breakdown|regulation of spindle disassembly during mitosis|regulation of mitotic spindle catabolism						al	2015-09-24T14:20:07Z						biological_process											owl:Class	
GO:1902056	biolink:NamedThing	(25S)-Delta(7)-dafachronate metabolic process	The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate.	got7fsn_ti	(25S)-Delta(7)-dafachronate metabolism						ab	2013-04-13T09:05:27Z						biological_process											owl:Class	
GO:1905466	biolink:NamedThing	negative regulation of G-quadruplex DNA unwinding	Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding.	got7fsn_ti	down-regulation of G-quadruplex DNA unwinding|downregulation of G-quadruplex DNA unwinding|inhibition of G-quadruplex DNA unwinding|down regulation of G-quadruplex DNA unwinding						ans	2016-09-19T12:15:53Z						biological_process											owl:Class	
PO:0005417	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904793	biolink:NamedThing	regulation of euchromatin binding	Any process that modulates the frequency, rate or extent of euchromatin binding.	got7fsn_ti							nc	2015-11-09T11:43:04Z						biological_process											owl:Class	
GO:0071646	biolink:NamedThing	regulation of macrophage inflammatory protein-1 gamma production	Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.	got7fsn_ti	regulation of MIP-1g production|regulation of CCL9 production|regulation of chemokine (C-C motif) ligand 9 production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:0005061	biolink:NamedThing	obsolete aryl hydrocarbon receptor nuclear translocator activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	aryl hydrocarbon receptor nuclear translocator activity				This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1990703	biolink:NamedThing	integral component of Golgi medial cisterna membrane	The component of the Golgi medial membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral component of medial-Golgi cisterna membrane						bhm	2015-03-16T16:05:25Z						cellular_component											owl:Class	
GO:1902221	biolink:NamedThing	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid.	got7fsn_ti	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolism						pr	2013-06-13T10:37:38Z						biological_process											owl:Class	
GO:0042895	biolink:NamedThing	obsolete antibiotic transmembrane transporter activity	OBSOLETE. Enables the transfer of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, from one side of a membrane to the other.	got7fsn_ti	antibiotic transporter activity	https://github.com/geneontology/go-ontology/issues/17082			The reason for obsoletion is that this term has been inconsistently used. Consider annotating to 'GO:0042910 ; xenobiotic transmembrane transporter activity' and the specific solute being transported as an annotation extension.					True				molecular_function											owl:Class	
GO:1905876	biolink:NamedThing	positive regulation of postsynaptic density organization	Any process that activates or increases the frequency, rate or extent of postsynaptic density organization.	got7fsn_ti	activation of postsynaptic density organisation|upregulation of postsynaptic density organization|up-regulation of PSD organization|upregulation of post-synaptic density organization|positive regulation of post-synaptic density organization|up-regulation of postsynaptic density organization|up-regulation of post-synaptic density organization|upregulation of PSD organization|up regulation of postsynaptic density organization|activation of postsynaptic density organization|up regulation of PSD organization|activation of post synaptic density organization|positive regulation of postsynaptic density organisation|up regulation of postsynaptic density organisation|upregulation of post synaptic density organization|up regulation of post synaptic density organization|up-regulation of postsynaptic density organisation|activation of PSD organization|up regulation of post-synaptic density organization|positive regulation of PSD organization|positive regulation of post synaptic density organization|up-regulation of post synaptic density organization|activation of post-synaptic density organization|upregulation of postsynaptic density organisation						sl	2017-01-27T19:53:50Z						biological_process											owl:Class	
GO:1903999	biolink:NamedThing	negative regulation of eating behavior	Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.	got7fsn_ti	downregulation of eating behavior|down regulation of eating behaviour|down regulation of eating behavior|down-regulation of eating behavior|downregulation of eating behaviour|down-regulation of eating behaviour|inhibition of eating behavior|negative regulation of eating behaviour|inhibition of eating behaviour						sl	2015-03-05T20:40:28Z						biological_process											owl:Class	
GO:2001129	biolink:NamedThing	methane biosynthetic process from dimethylamine	The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine.	got7fsn_ti							jl	2011-10-13T10:26:13Z						biological_process											owl:Class	
GO:0002760	biolink:NamedThing	positive regulation of antimicrobial humoral response	Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.	got7fsn_ti	up regulation of antimicrobial humoral response|activation of antimicrobial humoral response|up-regulation of antimicrobial humoral response|upregulation of antimicrobial humoral response|stimulation of antimicrobial humoral response													biological_process											owl:Class	
GO:2001197	biolink:NamedThing	basement membrane assembly involved in embryonic body morphogenesis	Any basement membrane assembly that is involved in embryonic body morphogenesis.	got7fsn_ti							kmv	2011-11-03T08:44:33Z						biological_process											owl:Class	
GO:0002302	biolink:NamedThing	CD8-positive, alpha-beta T cell differentiation involved in immune response	The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	got7fsn_ti	CD8-positive, alpha-beta T lymphocyte differentiation during immune response|CD8-positive, alpha-beta intraepithelial T cell development|CD8-positive, alpha-beta T cell differentiation during immune response|CD8-positive, alpha-beta T-cell differentiation during immune response|CD8-positive, alpha-beta T-lymphocyte differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0005546	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate binding	Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.	got7fsn_ti	PIP2 binding|phosphatidylinositol 4,5-bisphosphate binding|PtdIns(4,5)P2 binding|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding													molecular_function											owl:Class	
GO:1905372	biolink:NamedThing	ceramide phosphoethanolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine.	got7fsn_ti	ceramide phosphoethanolamine catabolism|ceramide phosphoethanolamine degradation|ceramide phosphoethanolamine breakdown						hjd	2016-08-16T17:11:04Z						biological_process											owl:Class	
GO:0006637	biolink:NamedThing	acyl-CoA metabolic process	The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.	got7fsn_ti	acyl-CoA metabolism													biological_process											owl:Class	
GO:1902655	biolink:NamedThing	aromatic primary alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic primary alcohol.	got7fsn_ti	aromatic primary alcohol synthesis|aromatic primary alcohol anabolism|aromatic primary alcohol formation|aromatic primary alcohol biosynthesis						tt	2014-01-22T10:47:30Z						biological_process											owl:Class	
GO:1904258	biolink:NamedThing	nuclear dicing body assembly	The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body.	got7fsn_ti	D body assembly|D body formation|nuclear dicing body formation						lr	2015-05-20T20:48:07Z						biological_process											owl:Class	
GO:0099019	biolink:NamedThing	maintenance of protein localization at growing cell tip	Any process in which localization of a protein is maintained at the growing cell tip.	got7fsn_ti	maintenance of protein location at growing cell tip						dos	2016-06-30T15:17:41Z						biological_process											owl:Class	
GO:0009338	biolink:NamedThing	exodeoxyribonuclease V complex	An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA.	got7fsn_ti														cellular_component											owl:Class	
GO:1903772	biolink:NamedThing	regulation of viral budding via host ESCRT complex	Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex.	got7fsn_ti	regulation of viral budding through the ESCRT machinery|regulation of host-assisted viral budding						als	2015-01-06T16:20:43Z						biological_process											owl:Class	
GO:0030886	biolink:NamedThing	negative regulation of myeloid dendritic cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation.	got7fsn_ti	down regulation of myeloid dendritic cell activation|downregulation of myeloid dendritic cell activation|inhibition of myeloid dendritic cell activation|down-regulation of myeloid dendritic cell activation													biological_process											owl:Class	
GO:0048436	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018334	biolink:NamedThing	obsolete enzyme active site formation via O4'-phospho-L-tyrosine	OBSOLETE. The transient phosphorylation of peptidyl-tyrosine to form O-phospho-L-tyrosine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it was created by error: O4'-phospho-L-tyrosine is a post-translational modification, see PMID:1725475.					True		RESID:AA0039		biological_process											owl:Class	
GO:0071506	biolink:NamedThing	cellular response to mycophenolic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.	got7fsn_ti	cellular response to mycophenolate						mah	2009-12-18T03:47:25Z						biological_process											owl:Class	
GO:0071660	biolink:NamedThing	positive regulation of IP-10 production	Any process that activates or increases the frequency, rate, or extent of production of IP-10.	got7fsn_ti	positive regulation of CXCL10 production|positive regulation of chemokine (C-C motif) ligand 10 production						mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:0062208	biolink:NamedThing	positive regulation of pattern recognition receptor signaling pathway	Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.	got7fsn_ti							dph	2020-02-03T14:45:27Z						biological_process											owl:Class	
GO:0120057	biolink:NamedThing	regulation of small intestinal transit	Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.	got7fsn_ti	regulation of small bowel transit|regulation of small intestine transit						krc	2017-06-13T20:56:46Z						biological_process											owl:Class	
GO:0015870	biolink:NamedThing	acetylcholine transport	The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.	got7fsn_ti														biological_process											owl:Class	
GO:0090062	biolink:NamedThing	regulation of trehalose metabolic process	Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	got7fsn_ti							tb	2009-08-12T11:24:29Z						biological_process											owl:Class	
GO:0006832	biolink:NamedThing	obsolete small molecule transport	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	small molecule transport				This term was made obsolete because it was an unnecessary grouping term.	GO:0006810				True				biological_process											owl:Class	
GO:0046237	biolink:NamedThing	obsolete phenanthrene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of phenanthrene, a tricyclic aromatic hydrocarbon.	got7fsn_ti	phenanthrene formation|phenanthrene biosynthetic process|phenanthrene synthesis|phenanthrene anabolism|phenanthrene biosynthesis			GO:0018955	This term was made obsolete because phenanthrene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0070404	biolink:NamedThing	NADH binding	Binding to the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.	got7fsn_ti	reduced nicotinamide adenine dinucleotide binding|NAD (reduced) binding|reduced NAD binding													molecular_function											owl:Class	
GO:0000019	biolink:NamedThing	regulation of mitotic recombination	Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.	got7fsn_ti	regulation of recombination within rDNA repeats													biological_process											owl:Class	
UBERON:0002492	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009441	biolink:NamedThing	glycolate metabolic process	The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid).	got7fsn_ti	glycolate metabolism											MetaCyc:GLYCOLATEMET-PWY		biological_process											owl:Class	
GO:0019393	biolink:NamedThing	glucarate biosynthetic process	The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid.	got7fsn_ti	glucarate formation|glucarate biosynthesis|glucarate synthesis|glucarate anabolism													biological_process											owl:Class	
GO:1903101	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.	got7fsn_ti	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolism|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate degradation|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate breakdown						bhm	2014-06-04T14:14:30Z						biological_process											owl:Class	
CHEBI:64712	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905927	biolink:NamedThing	obsolete regulation of invadopodium disassembly	OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium disassembly.	got7fsn_ti					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:38:57Z		True				biological_process											owl:Class	
GO:2001032	biolink:NamedThing	regulation of double-strand break repair via nonhomologous end joining	Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	got7fsn_ti	regulation of NHEJ						yaf	2011-08-24T09:25:39Z						biological_process											owl:Class	
GO:0006014	biolink:NamedThing	D-ribose metabolic process	The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.	got7fsn_ti	D-ribose metabolism													biological_process											owl:Class	
GO:0051153	biolink:NamedThing	regulation of striated muscle cell differentiation	Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0046370	biolink:NamedThing	fructose biosynthetic process	The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose.	got7fsn_ti	fructose synthesis|fructose formation|fructose anabolism|fructose biosynthesis													biological_process											owl:Class	
GO:0051548	biolink:NamedThing	negative regulation of keratinocyte migration	Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.	got7fsn_ti	inhibition of keratinocyte migration|down regulation of keratinocyte migration|downregulation of keratinocyte migration|down-regulation of keratinocyte migration													biological_process											owl:Class	
GO:0019667	biolink:NamedThing	anaerobic L-alanine catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP.	got7fsn_ti	L-alanine fermentation													biological_process											owl:Class	
GO:1904402	biolink:NamedThing	response to nocodazole	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.	got7fsn_ti							sl	2015-06-23T21:10:45Z						biological_process											owl:Class	
GO:0005724	biolink:NamedThing	obsolete nuclear telomeric heterochromatin	OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19086			This term was obsoleted because there is no heterochromatin at the telomere and the term had been used inconsistently.					True				cellular_component											owl:Class	
GO:0015294	biolink:NamedThing	solute:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0110037	biolink:NamedThing	regulation of nematode male tail tip morphogenesis	Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized.	got7fsn_ti							kmv	2017-07-24T20:21:34Z						biological_process											owl:Class	
GO:0002817	biolink:NamedThing	negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.	got7fsn_ti	down regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|downregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|down-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-positive bacteria													biological_process											owl:Class	
GO:0033231	biolink:NamedThing	carbohydrate export	The directed movement of carbohydrates out of a cell or organelle.	got7fsn_ti														biological_process											owl:Class	
GO:1901175	biolink:NamedThing	lycopene metabolic process	The chemical reactions and pathways involving lycopene.	got7fsn_ti	lycopene metabolism						yaf	2012-07-19T09:48:20Z						biological_process											owl:Class	
GO:0031439	biolink:NamedThing	positive regulation of mRNA cleavage	Any process that activates or increases the frequency, rate or extent of mRNA cleavage.	got7fsn_ti	upregulation of mRNA cleavage|up regulation of mRNA cleavage|activation of mRNA cleavage|up-regulation of mRNA cleavage|stimulation of mRNA cleavage													biological_process											owl:Class	
GO:1990866	biolink:NamedThing	obsolete response to sustained hypoxia	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sustained stimulus indicating lowered oxygen tension.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-09-25T15:18:11Z		True				biological_process											owl:Class	
CHEBI:35741	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900016	biolink:NamedThing	negative regulation of cytokine production involved in inflammatory response	Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.	got7fsn_ti	down regulation of cytokine production involved in acute inflammatory response|negative regulation of cytokine production involved in acute inflammatory response|down regulation of cytokine production involved in inflammatory response						rph	2012-01-11T09:34:31Z						biological_process											owl:Class	
GO:0052406	biolink:NamedThing	obsolete metabolism by host of symbiont carbohydrate	OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0060753	biolink:NamedThing	regulation of mast cell chemotaxis	Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.	got7fsn_ti							dph	2009-06-22T02:36:06Z						biological_process											owl:Class	
GO:0110043	biolink:NamedThing	positive regulation of pharynx morphogenesis	Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis.	got7fsn_ti							kmv	2017-07-24T21:09:48Z						biological_process											owl:Class	
GO:0019792	biolink:NamedThing	obsolete APG12 hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	APG12 hydrolase activity				This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True				molecular_function											owl:Class	
CHEBI:60102	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900725	biolink:NamedThing	osmoregulated periplasmic glucan metabolic process	The chemical reactions and pathways involving osmoregulated periplasmic glucan.	got7fsn_ti	osmoregulated periplasmic glucan metabolism						jl	2012-05-24T03:18:32Z						biological_process											owl:Class	
GO:0052012	biolink:NamedThing	obsolete catabolism by symbiont of host cell wall chitin	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of host cell wall chitin	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
CHEBI:29105	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901840	biolink:NamedThing	negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.	got7fsn_ti	downregulation of RNA polymerase I regulatory region sequence-specific DNA binding|down regulation of RNA polymerase I regulatory region sequence-specific DNA binding|inhibition of RNA polymerase I regulatory region sequence-specific DNA binding|down-regulation of RNA polymerase I regulatory region sequence-specific DNA binding						sart	2013-01-23T10:24:37Z						biological_process											owl:Class	
GO:0004251	biolink:NamedThing	obsolete X-Pro dipeptidase activity	OBSOLETE. Catalysis of the hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.	got7fsn_ti	peptidase D|prolidase activity|proline dipeptidase activity|Xaa-Pro dipeptidase activity|imidodipeptidase activity|gamma-peptidase activity|X-Pro dipeptidase activity				This term was made obsolete because it represents a gene product.	GO:0016805|GO:0008235				True		MetaCyc:3.4.13.9-RXN|EC:3.4.13.9		molecular_function											owl:Class	
GO:1990804	biolink:NamedThing	obsolete protein phosphorylation involved in double-strand break repair via nonhomologous end joining	OBSOLETE. Any protein phosphorylation process that is required for double-strand break repair via nonhomologous end joining.	got7fsn_ti	protein amino acid phosphorylation involved in NHEJ|protein amino acid phosphorylation involved in double-strand break repair via nonhomologous end joining|protein phosphorylation involved in NHEJ	https://github.com/geneontology/go-ontology/issues/14137			This term has been obsoleted because it represents a GO-CAM model.		rb	2015-07-16T21:54:01Z		True				biological_process											owl:Class	
GO:0009154	biolink:NamedThing	purine ribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine ribonucleotide breakdown|purine ribonucleotide degradation|purine ribonucleotide catabolism													biological_process											owl:Class	
GO:2000073	biolink:NamedThing	regulation of cytokinesis, site selection	Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis.	got7fsn_ti	regulation of site selection involved in cell cycle cytokinesis						tb	2010-08-27T11:15:15Z						biological_process											owl:Class	
GO:0070394	biolink:NamedThing	lipoteichoic acid metabolic process	The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	got7fsn_ti	LTA metabolic process|lipoteichoic acid metabolism													biological_process											owl:Class	
GO:1904295	biolink:NamedThing	regulation of osmolarity-sensing cation channel activity	Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity.	got7fsn_ti							sl	2015-06-09T17:35:40Z						biological_process											owl:Class	
CHEBI:17992	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001637	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018587	biolink:NamedThing	obsolete limonene 8-monooxygenase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	limonene 8-monooxygenase activity			GO:0019113	This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.					True				molecular_function											owl:Class	
PR:000001131	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903271	biolink:NamedThing	negative regulation of cytoplasmic translational elongation through polyproline stretches	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.	got7fsn_ti	down regulation of cytoplasmic translational elongation through polyproline stretches|down-regulation of cytoplasmic translational elongation through polyproline stretches|downregulation of cytoplasmic translational elongation through polyproline stretches|inhibition of cytoplasmic translational elongation through polyproline stretches						mcc	2014-08-08T14:54:08Z						biological_process											owl:Class	
GO:0032886	biolink:NamedThing	regulation of microtubule-based process	Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.	got7fsn_ti														biological_process											owl:Class	
GO:0045631	biolink:NamedThing	regulation of mechanoreceptor differentiation	Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1900321	biolink:NamedThing	regulation of maltotetraose transport	Any process that modulates the frequency, rate or extent of maltotetraose transport.	got7fsn_ti							tt	2012-04-06T01:45:36Z						biological_process											owl:Class	
GO:0098558	biolink:NamedThing	lumenal side of smooth endoplasmic reticulum membrane	The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen.	got7fsn_ti							dos	2013-12-03T12:19:28Z						cellular_component											owl:Class	
GO:0004200	biolink:NamedThing	obsolete signaling (initiator) caspase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	signalling (initiator) caspase activity|signaling (initiator) caspase activity			GO:0004197	This term was made obsolete because it includes biological process information.	GO:0006915				True				molecular_function											owl:Class	
GO:1901941	biolink:NamedThing	(+)-epi-alpha-bisabolol metabolic process	The chemical reactions and pathways involving (+)-epi-alpha-bisabolol.	got7fsn_ti	(+)-epi-alpha-bisabolol metabolism						ms	2013-02-18T14:55:36Z						biological_process											owl:Class	
GO:0002732	biolink:NamedThing	positive regulation of dendritic cell cytokine production	Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.	got7fsn_ti	up regulation of dendritic cell cytokine production|stimulation of dendritic cell cytokine production|upregulation of dendritic cell cytokine production|up-regulation of dendritic cell cytokine production|activation of dendritic cell cytokine production													biological_process											owl:Class	
GO:0016172	biolink:NamedThing	obsolete antifreeze activity	OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures.	got7fsn_ti	antifreeze activity				This term was made obsolete because it refers to a biological process.	GO:0050825|GO:0050826|GO:0042309				True				molecular_function											owl:Class	
GO:0030365	biolink:NamedThing	obsolete cleavage stimulation factor activity	OBSOLETE. A factor is necessary for cleavage but not for poly(A) addition in mRNA 3' end processing; can stimulate poly(A) addition on substrates with a CstF binding site upstream of the AAUAAA hexanucleotide.	got7fsn_ti	CstF|cleavage stimulation factor activity			GO:0005848	This term was made obsolete because it describes a cellular component.	GO:0006379				True				molecular_function											owl:Class	
GO:1901449	biolink:NamedThing	negative regulation of response to butan-1-ol	Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol.	got7fsn_ti	inhibition of response to butan-1-ol|down regulation of response to butan-1-ol|down-regulation of response to butan-1-ol|downregulation of response to butan-1-ol						tt	2012-10-02T14:16:59Z						biological_process											owl:Class	
CHEBI:27798	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075301	biolink:NamedThing	obsolete cell differentiation involved in spore germination	OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a specific cell type occurring during spore germination, the physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth.	got7fsn_ti					This term was made obsolete because it describes a process that doesn't exist.					True				biological_process											owl:Class	
GO:0071344	biolink:NamedThing	diphosphate metabolic process	The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid.	got7fsn_ti	pyrophosphate metabolism						mah	2009-12-11T01:43:41Z						biological_process											owl:Class	
GO:0052468	biolink:NamedThing	obsolete modulation by organism of salicylic acid levels in symbiont	OBSOLETE. The alteration by an organism of the levels of salicylic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of salicylic acid levels in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0032848	biolink:NamedThing	negative regulation of cellular pH reduction	Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell.	got7fsn_ti	inhibition of cellular pH reduction|down regulation of cellular pH reduction|negative regulation of reduction of cellular pH|downregulation of cellular pH reduction|negative regulation of cellular acidification|negative regulation of reduction of pH in cell|negative regulation of intracellular pH reduction|negative regulation of intracellular acidification|negative regulation of cell pH reduction|down-regulation of cellular pH reduction													biological_process											owl:Class	
GO:0072390	biolink:NamedThing	phenol metabolic process	The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group.	got7fsn_ti							mah	2010-12-06T04:05:51Z						biological_process											owl:Class	
GO:1905248	biolink:NamedThing	obsolete regulation of memory	OBSOLETE. Any process that modulates the frequency, rate or extent of memory.	got7fsn_ti	modulation of memory				This term was obsoleted at the TermGenie Gatekeeper stage.		ha	2016-06-09T13:54:38Z		True				biological_process											owl:Class	
GO:2001173	biolink:NamedThing	regulation of histone H2B conserved C-terminal lysine ubiquitination	Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.	got7fsn_ti	regulation of budding yeast H2B K123 ubiquitination|regulation of mammalian H2B K120 ubiquitination|regulation of fission yeast H2B K119 ubiquitination						se	2011-10-29T06:28:47Z						biological_process											owl:Class	
GO:0071869	biolink:NamedThing	response to catecholamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.	got7fsn_ti	response to catecholamine stimulus						mah	2010-09-13T02:51:13Z						biological_process											owl:Class	
GO:0000038	biolink:NamedThing	very long-chain fatty acid metabolic process	The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.	got7fsn_ti	very long chain fatty acid metabolic process|very-long-chain fatty acid metabolic process|very-long-chain fatty acid metabolism													biological_process											owl:Class	
GO:0106184	biolink:NamedThing	obsolete translocation activity acting on other compounds	OBSOLETE. Catalysis of the translocation of other compounds not included in EC:7.1 through EC:7.5 .	got7fsn_ti					This term was made obsolete because the name and scope ( other compounds not included in EC:7.1 through EC:7.5 ) is not good ontological practice.		hjd	2019-04-05T15:56:19Z		True		EC:7.6.-.-		molecular_function											owl:Class	
GO:1905374	biolink:NamedThing	response to homocysteine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.	got7fsn_ti	response to 2-amino-4-sulfanylbutanoic acid|response to 2-amino-4-mercaptobutyric acid|response to Hcy						sl	2016-08-17T20:17:53Z						biological_process											owl:Class	
GO:0030162	biolink:NamedThing	regulation of proteolysis	Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.	got7fsn_ti	regulation of peptidolysis													biological_process											owl:Class	
GO:1904437	biolink:NamedThing	positive regulation of transferrin receptor binding	Any process that activates or increases the frequency, rate or extent of transferrin receptor binding.	got7fsn_ti	activation of transferrin receptor binding|upregulation of transferrin receptor binding|up-regulation of transferrin receptor binding|up regulation of transferrin receptor binding						kom	2015-07-06T13:49:13Z						biological_process											owl:Class	
GO:0001598	biolink:NamedThing	obsolete chemokine receptor-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	chemokine receptor-like receptor activity				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True				molecular_function											owl:Class	
GO:0015345	biolink:NamedThing	ferric enterobactin:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in).	got7fsn_ti	ferric enterobactin:hydrogen symporter activity|ferric-enterobactin:proton symporter activity													molecular_function											owl:Class	
GO:0070907	biolink:NamedThing	histidine:histamine antiporter activity	Catalysis of the reaction: histidine(out) + histamine(in) = histidine(in) + histamine(out).	got7fsn_ti	histidine-histamine antiporter activity|histidine/histamine antiporter activity						mah	2009-09-04T03:47:07Z						molecular_function											owl:Class	
GO:1901344	biolink:NamedThing	response to leptomycin B	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.	got7fsn_ti							mah	2012-09-07T13:20:47Z						biological_process											owl:Class	
GO:0043238	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904422	biolink:NamedThing	cellular response to D-galactosamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.	got7fsn_ti							sl	2015-07-02T15:38:36Z						biological_process											owl:Class	
GO:0071233	biolink:NamedThing	cellular response to leucine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.	got7fsn_ti							mah	2009-12-03T02:09:26Z						biological_process											owl:Class	
GO:1903443	biolink:NamedThing	cellular response to lipoic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.	got7fsn_ti							jl	2014-09-17T13:52:12Z						biological_process											owl:Class	
GO:0099171	biolink:NamedThing	presynaptic modulation of chemical synaptic transmission	Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.	got7fsn_ti							dos	2017-09-11T17:09:31Z						biological_process											owl:Class	
GO:1904664	biolink:NamedThing	negative regulation of N-terminal peptidyl-methionine acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.	got7fsn_ti							vw	2015-09-07T19:18:56Z						biological_process											owl:Class	
GO:0033223	biolink:NamedThing	2-aminoethylphosphonate transport	The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	ciliatine transport|2-phosphonoethylamine transport													biological_process											owl:Class	
GO:0015121	biolink:NamedThing	phosphoenolpyruvate:phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out).	got7fsn_ti	PPT|phosphoenolpyruvate/phosphate translocator													molecular_function											owl:Class	
GO:1900673	biolink:NamedThing	olefin metabolic process	The chemical reactions and pathways involving olefin.	got7fsn_ti	olefin metabolism						tt	2012-05-22T04:24:42Z						biological_process											owl:Class	
GO:1903063	biolink:NamedThing	negative regulation of reverse cholesterol transport	Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport.	got7fsn_ti	down-regulation of reverse cholesterol transport|downregulation of reverse cholesterol transport|inhibition of reverse cholesterol transport|down regulation of reverse cholesterol transport						rl	2014-05-28T15:15:34Z						biological_process											owl:Class	
GO:1902508	biolink:NamedThing	2-iminoacetate synthase complex	A protein complex which is capable of 2-iminoacetate synthase activity.	got7fsn_ti	ThiH-ThiG complex						bhm	2013-11-14T16:56:44Z						cellular_component											owl:Class	
GO:0000108	biolink:NamedThing	obsolete repairosome	OBSOLETE. A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of nucleotide excision repair (NER), such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage.	got7fsn_ti	repairosome			GO:0000109	This term was made obsolete because 'repairosome' has fallen out of use in the literature, and the large complex described in the definition has not been confirmed to exist. The term has also confused annotators.					True				cellular_component											owl:Class	
UBERON:0005078	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015504	biolink:NamedThing	cytosine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).	got7fsn_ti	cytosine:hydrogen ion symporter activity|cytosine permease activity													molecular_function											owl:Class	
GO:0010808	biolink:NamedThing	positive regulation of synaptic vesicle priming	Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0005973	biolink:NamedThing	obsolete fibrinogen beta chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	fibrinogen beta chain				This term was made obsolete because it represents a single gene product and not a complex.	GO:0005577				True	GO:0008006			cellular_component											owl:Class	
GO:0035498	biolink:NamedThing	carnosine metabolic process	The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).	got7fsn_ti	carnosine metabolism						bf	2010-04-29T01:19:52Z						biological_process											owl:Class	
GO:0061087	biolink:NamedThing	positive regulation of histone H3-K27 methylation	Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.	got7fsn_ti							dph	2010-04-26T01:23:52Z						biological_process											owl:Class	
GO:1902124	biolink:NamedThing	(+)-pinoresinol metabolic process	The chemical reactions and pathways involving (+)-pinoresinol.	got7fsn_ti	(+)-pinoresinol metabolism						ms	2013-05-21T08:49:10Z						biological_process											owl:Class	
GO:0075291	biolink:NamedThing	positive regulation of aplanospore formation	Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.	got7fsn_ti														biological_process											owl:Class	
GO:1900028	biolink:NamedThing	negative regulation of ruffle assembly	Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly.	got7fsn_ti	negative regulation of membrane ruffle formation|negative regulation of membrane ruffling|down regulation of membrane ruffle formation|down regulation of membrane ruffling|down regulation of ruffle assembly						yaf	2012-01-12T05:00:53Z						biological_process											owl:Class	
UBERON:0001737	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:147341	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070728	biolink:NamedThing	leucine binding	Binding to 2-amino-4-methylpentanoic acid.	got7fsn_ti	Leu binding						mah	2009-06-17T03:16:30Z						molecular_function											owl:Class	
GO:1902810	biolink:NamedThing	negative regulation of skeletal muscle fiber differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation.	got7fsn_ti	downregulation of skeletal muscle fiber differentiation|down regulation of skeletal muscle fiber differentiation|down-regulation of skeletal muscle fiber differentiation|inhibition of skeletal muscle fiber differentiation						mr	2014-03-26T21:18:32Z						biological_process											owl:Class	
GO:0075322	biolink:NamedThing	regulation of oomycete sporangium development	Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.	got7fsn_ti														biological_process											owl:Class	
GO:0007026	biolink:NamedThing	negative regulation of microtubule depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.	got7fsn_ti	down-regulation of microtubule depolymerization|microtubule rescue|inhibition of microtubule depolymerization|negative regulation of microtubule catastrophe|downregulation of microtubule depolymerization|down regulation of microtubule depolymerization|microtubule stabilization|negative regulation of microtubule disassembly													biological_process											owl:Class	
GO:0032063	biolink:NamedThing	negative regulation of translational initiation in response to osmotic stress	Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti	down regulation of translation initiation in response to osmotic stress|downregulation of translation initiation in response to osmotic stress|down-regulation of translation initiation in response to osmotic stress|inhibition of translation initiation in response to osmotic stress													biological_process											owl:Class	
GO:1900206	biolink:NamedThing	regulation of pronephric nephron tubule development	Any process that modulates the frequency, rate or extent of pronephric nephron tubule development.	got7fsn_ti							bf	2012-03-22T09:23:13Z						biological_process											owl:Class	
GO:0120085	biolink:NamedThing	transposon integration involved in RNA-mediated transposition	Any transposon integration that contributes to a process of RNA-mediated transposition.	got7fsn_ti	retrotransposon integration						krc	2017-07-07T22:17:32Z						biological_process											owl:Class	
GO:0000265	biolink:NamedThing	obsolete heterotrimeric G-protein GTPase, gamma-subunit	OBSOLETE. Smallest subunit of a heterotrimeric G-protein GTPase; associates tightly with the beta subunit.	got7fsn_ti	heterotrimeric G-protein GTPase, gamma-subunit				This term was made obsolete because it does not represent a molecular function.	GO:0003924|GO:0005834				True				molecular_function											owl:Class	
GO:0003675	biolink:NamedThing	obsolete protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	protein				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0015432	biolink:NamedThing	ABC-type bile acid transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate.	got7fsn_ti	ATPase-coupled bile acid transmembrane transporter activity|bile acid porter activity|ATP-dependent bile acid transmembrane transporter activity|bile acid-exporting ATPase activity											Reactome:R-HSA-194153|TC:3.A.1.207.2|Reactome:R-HSA-5678517|RHEA:50048|Reactome:R-HSA-193362		molecular_function											owl:Class	
GO:0032583	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0110146	biolink:NamedThing	magnetosome membrane	The lipid bilayer surrounding a magnetosome.	got7fsn_ti							kmv	2019-05-30T17:51:09Z						cellular_component											owl:Class	
GO:0006200	biolink:NamedThing	obsolete ATP catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	got7fsn_ti	ATP degradation|ATP hydrolysis|ATP catabolism|ATP breakdown				The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0016887				True		Wikipedia:ATP_hydrolysis		biological_process											owl:Class	
GO:1902625	biolink:NamedThing	obsolete negative regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of induction of conjugation with cellular fusion.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		mah	2014-01-16T13:52:24Z		True				biological_process											owl:Class	
GO:2000422	biolink:NamedThing	regulation of eosinophil chemotaxis	Any process that modulates the frequency, rate or extent of eosinophil chemotaxis.	got7fsn_ti							bf	2011-02-24T01:16:44Z						biological_process											owl:Class	
CHEBI:26188	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0038014	biolink:NamedThing	negative regulation of insulin receptor signaling pathway by insulin receptor internalization	Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation.	got7fsn_ti	negative regulation of insulin receptor signalling pathway by insulin receptor internalization|agonist-stimulated insulin receptor internalization						bf	2011-06-23T04:08:31Z						biological_process											owl:Class	
GO:0015382	biolink:NamedThing	sodium:sulfate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in).	got7fsn_ti	sodium:sulphate symporter activity|sodium:sulfate cotransporter activity											Reactome:R-HSA-433114|Reactome:R-HSA-433099		molecular_function											owl:Class	
GO:0060380	biolink:NamedThing	regulation of single-stranded telomeric DNA binding	Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.	got7fsn_ti	regulation of telomeric ssDNA binding													biological_process											owl:Class	
CHEBI:24848	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008554	biolink:NamedThing	P-type sodium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism.	got7fsn_ti	Na+-transporting ATPase activity|Na+-exporting ATPase activity|sodium-exporting ATPase activity, phosphorylative mechanism|Na(+)-transporting ATPase activity|sodium transport ATPase activity|sodium exporting ATPase activity, phosphorylative mechanism|sodium-translocating P-type ATPase activity|sodium transmembrane transporter activity, phosphorylative mechanism|sodium-exporting ATPase activity|Na(+)-exporting ATPase activity	https://github.com/geneontology/go-ontology/issues/21796			Note that RHEA:14633 represents both the ABC and the P-type sodium transporters.							MetaCyc:3.6.3.7-RXN|RHEA:14633|EC:7.2.2.3		molecular_function											owl:Class	
GO:0106056	biolink:NamedThing	regulation of calcineurin-mediated signaling	Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling.	got7fsn_ti							hjd	2017-09-18T16:44:05Z						biological_process											owl:Class	
GO:0048695	biolink:NamedThing	negative regulation of collateral sprouting of injured axon	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon.	got7fsn_ti	down-regulation of collateral sprouting of injured axon|inhibition of collateral sprouting of injured axon|downregulation of collateral sprouting of injured axon|down regulation of collateral sprouting of injured axon													biological_process											owl:Class	
GO:1901611	biolink:NamedThing	phosphatidylglycerol binding	Binding to phosphatidylglycerol.	got7fsn_ti							kmv	2012-11-12T21:18:24Z						molecular_function											owl:Class	
GO:2000325	biolink:NamedThing	obsolete regulation of nuclear receptor coactivator activity	OBSOLETE. Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.	got7fsn_ti	regulation of nuclear receptor transcription coactivator activity|regulation of ligand-dependent nuclear receptor transcription co-activator activity|regulation of ligand-dependent nuclear receptor transcription coactivator activity				This term was obsoleted because it represents a molecular function.		vk	2011-01-18T06:29:32Z		True				biological_process											owl:Class	
GO:0140271	biolink:NamedThing	hexose import across plasma membrane	The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-10-01T08:49:49Z						biological_process											owl:Class	
GO:1902329	biolink:NamedThing	bacterial-type DNA replication termination	Any DNA replication termination that is involved in bacterial-type DNA replication.	got7fsn_ti	DNA replication termination involved in bacterial-type DNA replication						jl	2013-07-25T10:48:10Z						biological_process											owl:Class	
CHEBI:58567	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042891	biolink:NamedThing	obsolete antibiotic transport	OBSOLETE. The directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17082			The reason for obsoletion is that this term has been inconsistently used. For export of an antibiotic by the organism that synthesizes it, consider 'GO:0140115 ; export across plasma membrane'. For export of an antibiotic by the target organism, consider 'GO:1990961 ; xenobiotic detoxification by transmembrane export across the plasma membrane'.					True				biological_process											owl:Class	
GO:0032307	biolink:NamedThing	negative regulation of prostaglandin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	got7fsn_ti	down regulation of prostaglandin secretion|inhibition of prostaglandin secretion|downregulation of prostaglandin secretion|negative regulation of prostacyclin secretion|down-regulation of prostaglandin secretion													biological_process											owl:Class	
GO:0046828	biolink:NamedThing	regulation of RNA import into nucleus	Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.	got7fsn_ti	regulation of RNA transport from cytoplasm to nucleus|regulation of RNA import into cell nucleus|regulation of RNA-nucleus import													biological_process											owl:Class	
GO:1902343	biolink:NamedThing	regulation of maltose transport	Any process that modulates the frequency, rate or extent of maltose transport.	got7fsn_ti							dph	2013-08-01T17:16:18Z						biological_process											owl:Class	
GO:1902789	biolink:NamedThing	cellular response to isooctane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.	got7fsn_ti							tt	2014-03-21T20:52:58Z						biological_process											owl:Class	
GO:0120046	biolink:NamedThing	regulation of protein localization to medial cortical node	Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node.	got7fsn_ti							krc	2017-06-02T17:29:23Z						biological_process											owl:Class	
GO:0046867	biolink:NamedThing	carotenoid transport	The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.	got7fsn_ti														biological_process											owl:Class	
GO:0071314	biolink:NamedThing	cellular response to cocaine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.	got7fsn_ti							mah	2009-12-10T04:53:20Z						biological_process											owl:Class	
GO:0018873	biolink:NamedThing	atrazine metabolic process	The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide.	got7fsn_ti	atrazine metabolism											UM-BBD_pathwayID:atr		biological_process											owl:Class	
GO:0010555	biolink:NamedThing	response to mannitol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.	got7fsn_ti	response to mannitol stimulus													biological_process											owl:Class	
CHEBI:18123	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150003	biolink:NamedThing	regulation of spontaneous synaptic transmission	Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission.	got7fsn_ti														biological_process											owl:Class	
GO:0061190	biolink:NamedThing	regulation of sclerotome development	Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.	got7fsn_ti							dph	2010-07-14T09:19:47Z						biological_process											owl:Class	
GO:0046296	biolink:NamedThing	glycolate catabolic process	The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).	got7fsn_ti	glycolate degradation|glycolate catabolism|glycolate breakdown													biological_process											owl:Class	
GO:1902834	biolink:NamedThing	regulation of proline import across plasma membrane	Any process that modulates the frequency, rate or extent of proline import into cell.	got7fsn_ti	regulation of proline import into cell						mah	2014-04-01T13:44:00Z						biological_process											owl:Class	
GO:0002271	biolink:NamedThing	plasmacytoid dendritic cell activation involved in immune response	A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	plasmacytoid dendritic cell activation during immune response													biological_process											owl:Class	
GO:0015528	biolink:NamedThing	lactose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).	got7fsn_ti	lactose, galactose:hydrogen symporter activity|lactose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0009352	biolink:NamedThing	obsolete dihydrolipoyl dehydrogenase complex	OBSOLETE. Complex that possesses dihydrolipoyl dehydrogenase activity.	got7fsn_ti	dihydrolipoyl dehydrogenase complex|dihydrolipoamide dehydrogenase complex				This term was made obsolete because the activity dihydrolipoamide dehydrogenase is held by a single protein (Lpd1 in yeast), which is one of the components of three different complexes: 2-oxoglutarate dehydrogenase, pyruvate dehydrogenase, and branch chain amino acid dehydrogenase, so dihydrolipoamide dehydrogenase is not a complex itself.	GO:0045240|GO:0045254|GO:0004148				True				cellular_component											owl:Class	
GO:0085018	biolink:NamedThing	obsolete maintenance of symbiont-containing vacuole by host	OBSOLETE. The process in which a host organism maintains the structure and function of a symbiont-containing vacuole. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides, and can serve to reduce pathogenicity of invading symbionts by restricting them to the vacuolar compartment.	got7fsn_ti	maintenance of vacuolar integrity during bacterial infection|maintenance of pathogen-containing vacuole|maintenance of parasitophorous vacuole	https://github.com/geneontology/go-ontology/issues/21742			This term has been obsoleted because there is no evidence that this process exists.		jl	2010-05-20T03:58:51Z		True				biological_process											owl:Class	
CHEBI:29985	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000166	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.	got7fsn_ti							dph	2010-10-05T01:07:39Z						biological_process											owl:Class	
GO:1901887	biolink:NamedThing	2-hydroxybenzoyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA.	got7fsn_ti	2-hydroxybenzoyl-CoA formation|2-hydroxybenzoyl-CoA synthesis|2-hydroxybenzoyl-CoA anabolism|2-hydroxybenzoyl-CoA biosynthesis						ms	2013-02-06T14:06:12Z						biological_process											owl:Class	
GO:1902412	biolink:NamedThing	regulation of mitotic cytokinesis	Any process that modulates the frequency, rate or extent of mitotic cytokinesis.	got7fsn_ti	regulation of cytokinesis after mitosis						jl	2013-09-12T14:11:49Z						biological_process											owl:Class	
GO:0046490	biolink:NamedThing	isopentenyl diphosphate metabolic process	The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.	got7fsn_ti	isopentenyl diphosphate metabolism|IPP metabolism|isopentenyl pyrophosphate metabolic process|IPP metabolic process|isopentenyl pyrophosphate metabolism													biological_process											owl:Class	
GO:0005624	biolink:NamedThing	obsolete membrane fraction	OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.	got7fsn_ti	membrane fraction				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0016020				True				cellular_component											owl:Class	
GO:1990004	biolink:NamedThing	obsolete XDP phosphatase activity	OBSOLETE. Catalysis of the reaction: XDP + H2O = XMP + phosphate.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20954			This term was obsoleted because there is no evidence that this reaction exist in vivo.		jl	2012-12-11T14:01:34Z		True				molecular_function											owl:Class	
CHEBI:16004	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098697	biolink:NamedThing	ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels	Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	got7fsn_ti							dos	2017-04-04T17:11:38Z						molecular_function											owl:Class	
GO:0097244	biolink:NamedThing	flavonol binding	Binding to a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone.	got7fsn_ti							pr	2012-02-17T03:50:45Z						molecular_function											owl:Class	
GO:0048397	biolink:NamedThing	positive regulation of intermediate mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination.	got7fsn_ti	up-regulation of intermediate mesodermal cell fate determination|stimulation of intermediate mesodermal cell fate determination|upregulation of intermediate mesodermal cell fate determination|up regulation of intermediate mesodermal cell fate determination|activation of intermediate mesodermal cell fate determination													biological_process											owl:Class	
CHEBI:23527	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0023010	biolink:NamedThing	obsolete regulation of initiation of T cell receptor signaling	OBSOLETE. Any process that modulates the frequency, rate or extent of the initiation of T cell receptor signaling.	got7fsn_ti	regulation of initiation of T cell receptor signalling|regulation of initiation of T cell receptor signaling				This term was made obsolete because the meaning of the term is ambiguous.	GO:0050856		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0070904	biolink:NamedThing	transepithelial L-ascorbic acid transport	The directed movement of L-ascorbic acid from one side of an epithelium to the other.	got7fsn_ti	transepithelial L-ascorbate transport|transepithelial vitamin C transport						mah	2009-09-03T02:21:25Z						biological_process											owl:Class	
GO:1905066	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in heart development	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.	got7fsn_ti	regulation of canonical Wnt-activated signaling pathway involved in heart development|regulation of canonical Wnt receptor signalling pathway involved in heart development|regulation of canonical Wnt receptor signaling pathway involved in heart development						bc	2016-03-21T12:46:56Z						biological_process											owl:Class	
GO:1904201	biolink:NamedThing	regulation of iodide transport	Any process that modulates the frequency, rate or extent of iodide transport.	got7fsn_ti							sl	2015-05-08T15:19:57Z						biological_process											owl:Class	
GO:0046832	biolink:NamedThing	negative regulation of RNA export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.	got7fsn_ti	downregulation of RNA export from nucleus|negative regulation of RNA export out of nucleus|down regulation of RNA export from nucleus|inhibition of RNA export from nucleus|negative regulation of RNA transport from nucleus to cytoplasm|down-regulation of RNA export from nucleus|negative regulation of RNA-nucleus export|negative regulation of RNA export from cell nucleus													biological_process											owl:Class	
GO:0140361	biolink:NamedThing	cyclic-GMP-AMP transmembrane import across plasma membrane	The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2019-07-02T15:49:24Z						biological_process											owl:Class	
GO:1902153	biolink:NamedThing	regulation of response to DNA damage checkpoint signaling	Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling.	got7fsn_ti	regulation of DNA damage checkpoint effector process|regulation of response to signal involved in DNA damage checkpoint						jl	2013-05-21T15:44:39Z						biological_process											owl:Class	
GO:1902135	biolink:NamedThing	(+)-secoisolariciresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol.	got7fsn_ti	(+)-secoisolariciresinol formation|(+)-secoisolariciresinol anabolism|(+)-secoisolariciresinol synthesis|(+)-secoisolariciresinol biosynthesis						ms	2013-05-21T08:50:14Z						biological_process											owl:Class	
GO:0014911	biolink:NamedThing	positive regulation of smooth muscle cell migration	Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.	got7fsn_ti														biological_process											owl:Class	
GO:0018952	biolink:NamedThing	parathion metabolic process	The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.	got7fsn_ti	parathion metabolism											UM-BBD_pathwayID:pthn		biological_process											owl:Class	
GO:2000927	biolink:NamedThing	regulation of cellodextrin catabolic process	Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.	got7fsn_ti	regulation of cellodextrin catabolism						tt	2011-08-01T12:41:29Z						biological_process											owl:Class	
GO:1901410	biolink:NamedThing	regulation of tetrapyrrole biosynthetic process from glutamate	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.	got7fsn_ti	regulation of tetrapyrrole formation from glutamate|regulation of tetrapyrrole anabolism from glutamate|regulation of tetrapyrrole biosynthesis from glutamate|regulation of tetrapyrrole synthesis from glutamate						tt	2012-10-01T16:20:56Z						biological_process											owl:Class	
GO:0106181	biolink:NamedThing	obsolete translocase activity acting on inorganic anions	OBSOLETE. Catalysis of the translocation of inorganic anions.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:50:54Z		True		EC:7.3.-.-		molecular_function											owl:Class	
IAO:0000231	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
GO:1904813	biolink:NamedThing	ficolin-1-rich granule lumen	Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.	got7fsn_ti	membrane-enclosed lumen of ficolin-1 rich granule|ficolin-1-rich granule membrane-enclosed lumen|membrane-enclosed lumen of ficolin granule|membrane-enclosed lumen of ficolin-1-rich granule						mec	2015-11-13T11:58:20Z						cellular_component											owl:Class	
GO:0075248	biolink:NamedThing	regulation of aeciospore formation	Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.	got7fsn_ti														biological_process											owl:Class	
GO:0090027	biolink:NamedThing	negative regulation of monocyte chemotaxis	Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.	got7fsn_ti							tb	2009-08-03T10:19:40Z						biological_process											owl:Class	
CHEBI:27789	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018880	biolink:NamedThing	4-chlorobiphenyl metabolic process	The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation.	got7fsn_ti	4-chlorobiphenyl metabolism											UM-BBD_pathwayID:cbp		biological_process											owl:Class	
GO:0006234	biolink:NamedThing	TTP biosynthetic process	The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate.	got7fsn_ti	TTP synthesis|TTP formation|TTP biosynthesis|TTP anabolism													biological_process											owl:Class	
GO:1902781	biolink:NamedThing	cellular response to nonane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.	got7fsn_ti							tt	2014-03-21T03:25:32Z						biological_process											owl:Class	
GO:0042358	biolink:NamedThing	thiamine diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.	got7fsn_ti	thiamine diphosphate catabolism|TPP catabolism|thiamin diphosphate catabolism|thiamin pyrophosphate catabolism|thiamin diphosphate degradation|thiamin diphosphate breakdown|TPP catabolic process|thiamine pyrophosphate catabolism|thiamin pyrophosphate catabolic process|thiamin diphosphate catabolic process|thiamine pyrophosphate catabolic process													biological_process											owl:Class	
GO:2001230	biolink:NamedThing	positive regulation of response to gamma radiation	Any process that activates or increases the frequency, rate or extent of response to gamma radiation.	got7fsn_ti	positive regulation of response to gamma ray|positive regulation of response to gamma-ray photon						yaf	2011-11-20T04:51:17Z						biological_process											owl:Class	
CHEBI:22297	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901128	biolink:NamedThing	gentamycin metabolic process	The chemical reactions and pathways involving gentamycin.	got7fsn_ti	gentamycin metabolism						yaf	2012-07-11T03:26:25Z						biological_process											owl:Class	
GO:0071316	biolink:NamedThing	cellular response to nicotine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.	got7fsn_ti							mah	2009-12-10T05:05:05Z						biological_process											owl:Class	
CHEBI:58414	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006846	biolink:NamedThing	acetate transport	The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1903868	biolink:NamedThing	regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.	got7fsn_ti	regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|regulation of MetF|regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|regulation of N(5,10)-methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|regulation of methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolic acid reductase activity|regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|regulation of methylenetetrahydrofolic acid reductase activity|regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|regulation of 5,10-CH(2)-H(4)folate reductase activity|regulation of N5,N10-methylenetetrahydrofolate reductase activity|regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|regulation of methylenetetrahydrofolate reductase (NADPH2)|regulation of methylenetetrahydrofolate reductase [NAD(P)H]|regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|regulation of N5,10-methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase activity|regulation of MTHFR activity|regulation of 5,10-CH2-H4folate reductase activity|regulation of N(5),N(10)-methylenetetrahydrofolate reductase activity						rph	2015-02-05T13:26:14Z						biological_process											owl:Class	
GO:0060570	biolink:NamedThing	negative regulation of peptide hormone processing	Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.	got7fsn_ti							dph	2009-04-29T03:24:55Z						biological_process											owl:Class	
GO:0043156	biolink:NamedThing	obsolete chromatin remodeling in response to cation stress	OBSOLETE. Structural changes to eukaryotic chromatin occurring as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22036			This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0019038	biolink:NamedThing	obsolete provirus	OBSOLETE. The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True		Wikipedia:Provirus		cellular_component											owl:Class	
UBERON:0001986	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000984	biolink:NamedThing	negative regulation of ATP citrate synthase activity	Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity.	got7fsn_ti	negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|negative regulation of adenosine triphosphate citrate lyase activity|negative regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|negative regulation of citrate-ATP lyase activity|negative regulation of citrate cleavage enzyme activity|negative regulation of ATP citrate (pro-S)-lyase activity|negative regulation of ATP-citric lyase activity|negative regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|negative regulation of ATP-citrate (pro-S)-lyase activity|negative regulation of citric cleavage enzyme activity|negative regulation of ATP-citrate (pro-S-)-lyase activity|negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|negative regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity						vk	2011-08-04T03:15:28Z						biological_process											owl:Class	
GO:0042179	biolink:NamedThing	nicotine biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.	got7fsn_ti	nicotine biosynthesis|nicotine synthesis|nicotine anabolism|nicotine formation													biological_process											owl:Class	
GO:1905799	biolink:NamedThing	regulation of intraciliary retrograde transport	Any process that modulates the frequency, rate or extent of intraciliary retrograde transport.	got7fsn_ti	regulation of intraflagellar retrograde transport						hbye	2017-01-11T12:58:18Z						biological_process											owl:Class	
GO:0046782	biolink:NamedThing	regulation of viral transcription	Any process that modulates the frequency, rate or extent of the transcription of the viral genome.	got7fsn_ti														biological_process											owl:Class	
GO:0006224	biolink:NamedThing	obsolete uridine kinase reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	uridine kinase reaction			GO:0004849	This term was made obsolete because it represents a molecular function.					True				biological_process											owl:Class	
GO:2001121	biolink:NamedThing	coenzyme gamma-F420-2 biosynthetic process	The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2.	got7fsn_ti	coenzyme gamma-F420-2 biosynthesis						jl	2011-10-11T02:38:14Z						biological_process											owl:Class	
GO:1900074	biolink:NamedThing	negative regulation of neuromuscular synaptic transmission	Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission.	got7fsn_ti	down regulation of neuromuscular synaptic transmission|down-regulation of neuromuscular synaptic transmission|downregulation of neuromuscular synaptic transmission|inhibition of neuromuscular synaptic transmission						kmv	2012-01-26T10:14:18Z						biological_process											owl:Class	
GO:1903497	biolink:NamedThing	cellular response to 11-deoxycorticosterone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.	got7fsn_ti							mr	2014-09-25T17:01:43Z						biological_process											owl:Class	
GO:0140147	biolink:NamedThing	zinc ion export from vacuole	The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol.	got7fsn_ti							pg	2017-12-13T15:21:10Z						biological_process											owl:Class	
GO:1903621	biolink:NamedThing	protein localization to photoreceptor connecting cilium	A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium.	got7fsn_ti	protein localisation in photoreceptor connecting cilium|protein localization in photoreceptor connecting cilium|protein localisation to photoreceptor connecting cilium						jl	2014-11-19T17:17:17Z						biological_process											owl:Class	
GO:1900060	biolink:NamedThing	negative regulation of ceramide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.	got7fsn_ti	down-regulation of ceramide biosynthesis|down-regulation of ceramide anabolism|down regulation of ceramide biosynthesis|down-regulation of ceramide synthesis|inhibition of ceramide formation|downregulation of ceramide biosynthesis|downregulation of ceramide anabolism|inhibition of ceramide anabolism|inhibition of ceramide synthesis|negative regulation of ceramide formation|downregulation of ceramide synthesis|inhibition of ceramide biosynthesis|negative regulation of ceramide synthesis|down-regulation of ceramide formation|downregulation of ceramide formation|negative regulation of ceramide anabolism|downregulation of ceramide biosynthetic process|down-regulation of ceramide biosynthetic process|inhibition of ceramide biosynthetic process|down regulation of ceramide formation|down regulation of ceramide anabolism|negative regulation of ceramide biosynthesis|down regulation of ceramide biosynthetic process|down regulation of ceramide synthesis						dph	2012-01-25T03:18:07Z						biological_process											owl:Class	
GO:0003694	biolink:NamedThing	obsolete plasmid binding	OBSOLETE. Interacting selectively with a plasmid, an extrachromosomal genetic element usually characterized as a covalently continuous double stranded DNA molecule found in bacteria and some other microorganisms.	got7fsn_ti	plasmid-associated protein|plasmid binding				This term was made obsolete because it refers to component information.	GO:0003677|GO:0005727				True				molecular_function											owl:Class	
GO:0019521	biolink:NamedThing	D-gluconate metabolic process	The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.	got7fsn_ti	D-gluconate metabolism													biological_process											owl:Class	
GO:1905751	biolink:NamedThing	positive regulation of endosome to plasma membrane protein transport	Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport.	got7fsn_ti	upregulation of endosome to plasma membrane protein transport|up regulation of endosome to plasma membrane protein transport|activation of endosome to plasma membrane protein transport|up-regulation of endosome to plasma membrane protein transport						pga	2016-12-09T13:46:30Z						biological_process											owl:Class	
GO:0120029	biolink:NamedThing	proton export across plasma membrane	The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region.	got7fsn_ti	hydrogen ion export from cell|hydrogen ion export across plasma membrane|proton export across plasma membrane|proton export from cell						krc	2017-03-31T17:39:03Z						biological_process											owl:Class	
GO:0006859	biolink:NamedThing	extracellular carbohydrate transport	The directed extracellular movement of carbohydrates.	got7fsn_ti														biological_process											owl:Class	
GO:0023069	biolink:NamedThing	obsolete signal transmission via xylem	OBSOLETE. The process in which a signal is conveyed via the xylem.	got7fsn_ti	signal transmission via xylem				This term was made obsolete because the meaning of the term is ambiguous.	GO:0010232|GO:0023052		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0000078	biolink:NamedThing	obsolete cytokinesis after mitosis checkpoint	OBSOLETE. A mitotic cell cycle checkpoint that detects whether chromosome segregation is complete and negatively regulates cytokinesis following mitosis.	got7fsn_ti	cell shape checkpoint|cell morphogenesis checkpoint				The reason this term was made obsolete is that the two terms cytokinesis checkpoint (GO:0031565) and cytokinesis after mitosis (GO:0000078) were conflated in meaning.	GO:0044879|GO:0044878				True				biological_process											owl:Class	
GO:0070800	biolink:NamedThing	negative regulation of conidiophore stalk development	Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.	got7fsn_ti							mah	2009-07-08T04:10:42Z						biological_process											owl:Class	
GO:0015253	biolink:NamedThing	obsolete sugar/polyol channel activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	sugar/polyol channel activity				This term was made obsolete because it represents two molecular functions.	GO:0051119|GO:0015166				True				molecular_function											owl:Class	
GO:0120255	biolink:NamedThing	olefinic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).	got7fsn_ti	alkene substituted compound anabolism|alkene substituted compound anabolic process|alkene substituted compound biosynthesis|alkene substituted compound biosynthetic process|alkene substituted compound synthesis	https://github.com/geneontology/go-ontology/issues/19936					krc	2020-09-02T23:30:20Z						biological_process											owl:Class	
CHEBI:57520	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075316	biolink:NamedThing	negative regulation of basidium development	Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0015964	biolink:NamedThing	diadenosine triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.	got7fsn_ti	diadenosine triphosphate breakdown|diadenosine triphosphate catabolism|diadenosine triphosphate degradation													biological_process											owl:Class	
GO:0100005	biolink:NamedThing	obsolete positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates ethanol catabolic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1902346	biolink:NamedThing	meiotic strand displacement involved in double-strand break repair via SDSA	Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA).	got7fsn_ti	meiotic D-loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing|meiotic displacement loop processing involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop processing involved in mitotic gene conversion|meiotic strand displacement involved in mitotic gene conversion|meiotic displacement loop processing involved in mitotic gene conversion|meiotic D-loop dissociation involved in mitotic gene conversion|meiotic displacement loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop processing involved in double-strand break repair via synthesis-dependent strand annealing|meiotic displacement loop dissociation involved in mitotic gene conversion|meiotic strand displacement involved in double-strand break repair via synthesis-dependent strand annealing|meiotic strand displacement involved in SDSA						pr	2013-08-07T12:56:20Z						biological_process											owl:Class	
GO:2001105	biolink:NamedThing	maltoheptaose transport	The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:31:22Z						biological_process											owl:Class	
GO:1902195	biolink:NamedThing	isovaleryl-CoA(4-) metabolic process	The chemical reactions and pathways involving isovaleryl-CoA(4-).	got7fsn_ti	isovaleryl-CoA(4-) metabolism						ms	2013-06-06T09:55:55Z						biological_process											owl:Class	
GO:0043295	biolink:NamedThing	glutathione binding	Binding to glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.	got7fsn_ti														molecular_function											owl:Class	
GO:1901146	biolink:NamedThing	mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis.	got7fsn_ti							pr	2012-07-13T02:40:43Z						biological_process											owl:Class	
GO:2000099	biolink:NamedThing	regulation of establishment or maintenance of bipolar cell polarity	Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity.	got7fsn_ti							dph	2010-09-14T04:40:51Z						biological_process											owl:Class	
GO:0017135	biolink:NamedThing	obsolete membrane-associated protein with guanylate kinase activity interacting	OBSOLETE. The interaction with synapse-associated membrane-associated protein with guanylate kinase activity.	got7fsn_ti	membrane-associated protein with guanylate kinase activity interacting				This term was made obsolete because it does not represent a molecular function and the term name appears to make no sense.	GO:0019899				True				molecular_function											owl:Class	
GO:1903415	biolink:NamedThing	flavonoid transport from endoplasmic reticulum to plant-type vacuole	The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole.	got7fsn_ti	flavonoid accumulation in vacuole						tb	2014-09-05T00:35:34Z						biological_process											owl:Class	
GO:0010655	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000202	biolink:NamedThing	obsolete MAPKKK cascade during sporulation (sensu Saccharomyces)	OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	got7fsn_ti	MAPKKK cascade during sporulation (sensu Saccharomyces)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0009214	biolink:NamedThing	cyclic nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.	got7fsn_ti	cyclic nucleotide breakdown|cyclic nucleotide catabolism|cyclic nucleotide degradation													biological_process											owl:Class	
GO:0150102	biolink:NamedThing	negative regulation of monocyte activation	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation.	got7fsn_ti	repression of monocyte activation						bc	2019-04-26T20:01:24Z						biological_process											owl:Class	
GO:0014048	biolink:NamedThing	regulation of glutamate secretion	Any process that modulates the frequency, rate or extent of the controlled release of glutamate.	got7fsn_ti														biological_process											owl:Class	
GO:0140354	biolink:NamedThing	lipid import into cell	The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.	got7fsn_ti	lipid uptake						pg	2019-05-22T11:38:15Z						biological_process											owl:Class	
GO:0019361	biolink:NamedThing	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.	got7fsn_ti	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA formation|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA anabolism|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA synthesis|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthesis											MetaCyc:P2-PWY		biological_process											owl:Class	
GO:0017170	biolink:NamedThing	obsolete KU70 binding	OBSOLETE. Binding to Ku70, a protein involved in non-homologous DNA end joining.	got7fsn_ti	KU70 binding				This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
CHEBI:72765	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900893	biolink:NamedThing	regulation of tridecane metabolic process	Any process that modulates the frequency, rate or extent of tridecane metabolic process.	got7fsn_ti	regulation of tridecane metabolism						tt	2012-06-13T03:14:40Z						biological_process											owl:Class	
GO:2000509	biolink:NamedThing	negative regulation of dendritic cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.	got7fsn_ti							ebc	2011-03-22T10:21:45Z						biological_process											owl:Class	
GO:0061951	biolink:NamedThing	establishment of protein localization to plasma membrane	The directed movement of a protein to a specific location in a plasma membrane.	got7fsn_ti							dph	2017-10-26T12:55:15Z						biological_process											owl:Class	
GO:0061945	biolink:NamedThing	regulation of protein K48-linked ubiquitination	Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.	got7fsn_ti							dph	2017-09-22T11:45:43Z						biological_process											owl:Class	
GO:0052363	biolink:NamedThing	obsolete catabolism by organism of protein in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism by organism of protein in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0010568	biolink:NamedThing	regulation of budding cell apical bud growth	Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding.	got7fsn_ti														biological_process											owl:Class	
GO:0003802	biolink:NamedThing	obsolete coagulation factor VIIa activity	OBSOLETE. Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa, and on factor IX to form factor IXa beta.	got7fsn_ti	blood-coagulation factor VIIa|activated blood coagulation factor VII|coagulation factor VIIa activity|blood coagulation factor VII activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1903907	biolink:NamedThing	negative regulation of plasma membrane raft polarization	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization.	got7fsn_ti	downregulation of plasma membrane raft polarization|down regulation of plasma membrane raft polarization|inhibition of plasma membrane raft polarization|down-regulation of plasma membrane raft polarization						als	2015-02-09T10:54:05Z						biological_process											owl:Class	
GO:0015845	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902809	biolink:NamedThing	regulation of skeletal muscle fiber differentiation	Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation.	got7fsn_ti							mr	2014-03-26T21:18:26Z						biological_process											owl:Class	
GO:0006550	biolink:NamedThing	isoleucine catabolic process	The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.	got7fsn_ti	isoleucine catabolism|isoleucine degradation|isoleucine breakdown											MetaCyc:ILEUDEG-PWY		biological_process											owl:Class	
GO:0006141	biolink:NamedThing	regulation of purine nucleobase metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines.	got7fsn_ti	regulation of purine base metabolism|regulation of purine base metabolic process													biological_process											owl:Class	
GO:0009801	biolink:NamedThing	cinnamic acid ester metabolic process	The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid.	got7fsn_ti	cinnamic acid ester metabolism													biological_process											owl:Class	
GO:0061092	biolink:NamedThing	positive regulation of phospholipid translocation	Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	got7fsn_ti							dph	2010-04-26T01:54:22Z						biological_process											owl:Class	
GO:0052342	biolink:NamedThing	obsolete catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	catabolism by organism of cell wall chitin in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:1901848	biolink:NamedThing	nicotinate catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotinate.	got7fsn_ti	nicotinate degradation|nicotinate breakdown|nicotinate catabolism						yaf	2013-01-28T11:23:52Z						biological_process											owl:Class	
GO:0046386	biolink:NamedThing	deoxyribose phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.	got7fsn_ti	deoxyribose phosphate breakdown|deoxyribose phosphate degradation|deoxyribose phosphate catabolism													biological_process											owl:Class	
GO:0042882	biolink:NamedThing	L-arabinose transmembrane transport	The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	L-arabinose transport													biological_process											owl:Class	
GO:0002592	biolink:NamedThing	regulation of antigen processing and presentation via MHC class Ib	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.	got7fsn_ti														biological_process											owl:Class	
GO:1904837	biolink:NamedThing	beta-catenin-TCF complex assembly	The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.	got7fsn_ti	beta-catenin/T-cell factor complex formation|beta-catenin/lymphoid enhancer binding factor complex assembly|beta-catenin/LEF complex assembly|beta-catenin-TCF complex formation|beta-catenin/lymphoid enhancer binding factor complex formation|beta-catenin/T-cell factor complex assembly|beta-catenin/LEF complex formation						bf	2015-12-03T17:20:26Z						biological_process											owl:Class	
GO:2000604	biolink:NamedThing	negative regulation of secondary growth	Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth.	got7fsn_ti							tb	2011-04-15T10:30:47Z						biological_process											owl:Class	
CHEBI:35581	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019450	biolink:NamedThing	L-cysteine catabolic process to pyruvate	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate.	got7fsn_ti	L-cysteine degradation to pyruvate|L-cysteine breakdown to pyruvate											MetaCyc:LCYSDEG-PWY		biological_process											owl:Class	
GO:1904270	biolink:NamedThing	pyroptosome complex assembly	The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex.	got7fsn_ti	ASC pyroptosome assembly|pyroptosome complex formation|ASC pyroptosome formation						lb	2015-05-29T08:25:45Z						biological_process											owl:Class	
GO:0099021	biolink:NamedThing	cortical endoplasmic reticulum lumen	The volume enclosed by the membranes of the cortical endoplasmic reticulum.	got7fsn_ti														cellular_component											owl:Class	
GO:0033322	biolink:NamedThing	homomethionine biosynthetic process	The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.	got7fsn_ti	homomethionine anabolism|homomethionine formation|homomethionine biosynthesis|homomethionine synthesis											MetaCyc:PWY-1186		biological_process											owl:Class	
GO:1905588	biolink:NamedThing	plant-type cell wall modification involved in stomatal movement	Any plant-type cell wall modification that is involved in stomatal movement.	got7fsn_ti	cellulose and pectin-containing cell wall modification involved in stomatal movement						lr	2016-10-25T00:29:26Z						biological_process											owl:Class	
CHEBI:64708	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032106	biolink:NamedThing	positive regulation of response to extracellular stimulus	Any process that activates, maintains or increases the rate of a response to an extracellular stimulus.	got7fsn_ti	activation of response to extracellular stimulus|up regulation of response to extracellular stimulus|upregulation of response to extracellular stimulus|stimulation of response to extracellular stimulus|up-regulation of response to extracellular stimulus													biological_process											owl:Class	
GO:0070270	biolink:NamedThing	obsolete mitotic catastrophe	OBSOLETE. A type of programmed cell death that occurs during or shortly after a dysregulated or failed mitosis and can be accompanied by morphological alterations including micronucleation and multinucleation.	got7fsn_ti	cell death preceded by multinucleation|mitotic catastrophe|cell death occurring during metaphase				This term was made obsolete because it does not refer to a true process, but rather to the consequences of aberrations occurred during mitosis.					True				biological_process											owl:Class	
GO:1903840	biolink:NamedThing	response to arsenite(3-)	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.	got7fsn_ti							mr	2015-01-22T19:49:25Z						biological_process											owl:Class	
GO:0033195	biolink:NamedThing	response to alkyl hydroperoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.	got7fsn_ti														biological_process											owl:Class	
GO:1900300	biolink:NamedThing	regulation of laminarabiose transport	Any process that modulates the frequency, rate or extent of laminarabiose transport.	got7fsn_ti							tt	2012-04-05T07:57:19Z						biological_process											owl:Class	
GO:1903673	biolink:NamedThing	mitotic cleavage furrow formation	Any cleavage furrow formation that is involved in mitotic cell cycle.	got7fsn_ti	cleavage furrow positioning involved in mitotic cell cycle						jl	2014-11-27T15:32:18Z						biological_process											owl:Class	
GO:0019747	biolink:NamedThing	regulation of isoprenoid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.	got7fsn_ti	regulation of isoprenoid metabolism													biological_process											owl:Class	
GO:2001084	biolink:NamedThing	L-arabinofuranose binding	Binding to L-arabinofuranose.	got7fsn_ti							jl	2011-09-15T01:33:53Z						molecular_function											owl:Class	
GO:0019476	biolink:NamedThing	D-lysine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.	got7fsn_ti	D-lysine degradation|D-lysine catabolism|D-lysine breakdown													biological_process											owl:Class	
GO:0016912	biolink:NamedThing	obsolete SAP kinase 5 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	SAPK5|SAP kinase 5 activity				This term was made obsolete because there are no known gene products that would be described as 'SAP kinase 5', and the term name implies that it refers to a gene product.	GO:0007254|GO:0004674				True				molecular_function											owl:Class	
GO:0052209	biolink:NamedThing	obsolete interaction with other organism via substance secreted by type IV secretion system involved in symbiotic interaction	OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type IV secretion system, where the two organisms are in a symbiotic interaction.	got7fsn_ti	interaction with other organism via substance secreted by type IV secretion system during symbiotic interaction				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:1901695	biolink:NamedThing	tyramine biosynthetic process	The chemical reactions and pathways resulting in the formation of tyramine.	got7fsn_ti	tyramine anabolism|tyramine biosynthesis|tyramine formation|tyramine synthesis						tb	2012-12-12T19:31:35Z						biological_process											owl:Class	
GO:1902750	biolink:NamedThing	negative regulation of cell cycle G2/M phase transition	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.	got7fsn_ti	down-regulation of cell cycle G2/M phase transition|inhibition of cell cycle G2/M phase transition|down regulation of cell cycle G2/M phase transition|downregulation of cell cycle G2/M phase transition						jl	2014-03-05T15:38:21Z						biological_process											owl:Class	
GO:0070814	biolink:NamedThing	hydrogen sulfide biosynthetic process	The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.	got7fsn_ti	hydrogen sulfide formation|hydrogen sulfide synthesis|hydrogen sulfide biosynthesis|hydrogen sulphide biosynthetic process|hydrogen sulfide anabolism|hydrogen sulphide biosynthesis						mah	2009-07-09T10:45:02Z						biological_process											owl:Class	
GO:0032949	biolink:NamedThing	regulation of alpha-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans.	got7fsn_ti	regulation of alpha-glucan formation|regulation of alpha-glucan biosynthesis|regulation of alpha-glucan synthesis|regulation of alpha-glucan anabolism													biological_process											owl:Class	
GO:1905406	biolink:NamedThing	positive regulation of mitotic cohesin loading	Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading.	got7fsn_ti							vw	2016-08-25T14:49:01Z						biological_process											owl:Class	
GO:0005505	biolink:NamedThing	obsolete heavy metal binding	OBSOLETE. Interacting selectively with a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	got7fsn_ti	heavy metal binding				This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0046872				True				molecular_function											owl:Class	
GO:0004716	biolink:NamedThing	obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	got7fsn_ti	receptor signalling protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity	https://github.com/geneontology/go-ontology/issues/14232			This term was obsoleted because it was not clearly defined.					True		EC:2.7.10.-		molecular_function											owl:Class	
GO:0034153	biolink:NamedThing	positive regulation of toll-like receptor 6 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway.	got7fsn_ti	positive regulation of toll-like receptor 6 signalling pathway|positive regulation of TLR6 signaling pathway													biological_process											owl:Class	
GO:1901878	biolink:NamedThing	positive regulation of calcium ion binding	Any process that activates or increases the frequency, rate or extent of calcium ion binding.	got7fsn_ti	up regulation of calcium ion binding|activation of calcium ion storage activity|positive regulation of calcium ion storage activity|up-regulation of calcium ion binding|upregulation of calcium ion binding|activation of calcium ion binding|up-regulation of calcium ion storage activity|up regulation of calcium ion storage activity|upregulation of calcium ion storage activity						rl	2013-02-06T12:38:26Z						biological_process											owl:Class	
GO:0052350	biolink:NamedThing	obsolete induction by organism of induced systemic resistance in symbiont	OBSOLETE. Any process in which an organism activates induced systemic resistance in the symbiont; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of ISR in symbiont|induction by organism of induced systemic resistance in symbiont|activation by organism of induced systemic resistance in symbiont|induction by organism of ISR in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1905441	biolink:NamedThing	response to chondroitin 4'-sulfate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.	got7fsn_ti							cvs	2016-09-14T18:56:27Z						biological_process											owl:Class	
GO:1904297	biolink:NamedThing	positive regulation of osmolarity-sensing cation channel activity	Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity.	got7fsn_ti	up regulation of osmolarity-sensing cation channel activity|up-regulation of osmolarity-sensing cation channel activity|activation of osmolarity-sensing cation channel activity|upregulation of osmolarity-sensing cation channel activity						sl	2015-06-09T17:35:52Z						biological_process											owl:Class	
GO:2000952	biolink:NamedThing	negative regulation of xyloglucan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process.	got7fsn_ti	negative regulation of xyloglucan catabolism						tt	2011-08-01T02:20:21Z						biological_process											owl:Class	
GO:1901707	biolink:NamedThing	leptomycin B binding	Binding to leptomycin B.	got7fsn_ti							mah	2012-12-18T15:10:04Z						molecular_function											owl:Class	
GO:1905826	biolink:NamedThing	negative regulation of selenocysteine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process.	got7fsn_ti	inhibition of selenocysteine metabolism|down-regulation of selenocysteine metabolic process|down-regulation of selenocysteine metabolism|down regulation of selenocysteine metabolic process|downregulation of selenocysteine metabolism|down regulation of selenocysteine metabolism|negative regulation of selenocysteine metabolism|downregulation of selenocysteine metabolic process|inhibition of selenocysteine metabolic process						sl	2017-01-16T19:01:42Z						biological_process											owl:Class	
GO:0098948	biolink:NamedThing	intrinsic component of postsynaptic specialization membrane	The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to postsynaptic specialization membrane													cellular_component											owl:Class	
GO:1903311	biolink:NamedThing	regulation of mRNA metabolic process	Any process that modulates the frequency, rate or extent of mRNA metabolic process.	got7fsn_ti	regulation of mRNA metabolism						vw	2014-08-18T11:52:26Z						biological_process											owl:Class	
GO:1902261	biolink:NamedThing	positive regulation of delayed rectifier potassium channel activity	Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity.	got7fsn_ti	activation of delayed rectifier potassium channel activity|up regulation of delayed rectifier potassium channel activity|upregulation of delayed rectifier potassium channel activity|up-regulation of delayed rectifier potassium channel activity						rl	2013-06-25T12:16:30Z						biological_process											owl:Class	
GO:2001036	biolink:NamedThing	negative regulation of tongue muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.	got7fsn_ti							yaf	2011-08-24T11:10:20Z						biological_process											owl:Class	
UBERON:0003382	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904648	biolink:NamedThing	cellular response to rotenone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.	got7fsn_ti							sl	2015-08-31T20:55:39Z						biological_process											owl:Class	
GO:0075211	biolink:NamedThing	obsolete regulation of transmembrane receptor-mediated cAMP signaling in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host|regulation of transmembrane receptor-mediated cAMP signalling in response to host|regulation of transmembrane receptor-mediated cAMP signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0052352	biolink:NamedThing	obsolete biosynthesis by host of substance in symbiont	OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont resulting in the formation of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18787			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0120073	biolink:NamedThing	negative regulation of pyloric antrum smooth muscle contraction	Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.	got7fsn_ti							krc	2017-06-13T23:33:11Z						biological_process											owl:Class	
GO:1905245	biolink:NamedThing	regulation of aspartic-type peptidase activity	Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity.	got7fsn_ti							jl	2016-06-09T11:55:39Z						biological_process											owl:Class	
GO:1901176	biolink:NamedThing	lycopene catabolic process	The chemical reactions and pathways resulting in the breakdown of lycopene.	got7fsn_ti	lycopene breakdown|lycopene catabolism|lycopene degradation						yaf	2012-07-19T09:48:41Z						biological_process											owl:Class	
GO:0042400	biolink:NamedThing	ectoine catabolic process	The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.	got7fsn_ti	ectoine degradation|ectoine catabolism|ectoine breakdown													biological_process											owl:Class	
GO:0014013	biolink:NamedThing	regulation of gliogenesis	Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.	got7fsn_ti														biological_process											owl:Class	
GO:0090229	biolink:NamedThing	negative regulation of red or far-red light signaling pathway	Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.	got7fsn_ti	negative regulation of red or far-red light signalling pathway|negative regulation of phytochrome signaling pathway						tb	2010-01-19T04:03:29Z						biological_process											owl:Class	
GO:0031999	biolink:NamedThing	negative regulation of fatty acid beta-oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.	got7fsn_ti	downregulation of fatty acid beta-oxidation|down regulation of fatty acid beta-oxidation|inhibition of fatty acid beta-oxidation|down-regulation of fatty acid beta-oxidation													biological_process											owl:Class	
GO:0010889	biolink:NamedThing	regulation of sequestering of triglyceride	Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.	got7fsn_ti	regulation of sequestering of triacylglycerol|regulation of triacylglycerol sequestration													biological_process											owl:Class	
UBERON:0002336	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098574	biolink:NamedThing	cytoplasmic side of lysosomal membrane	The side (leaflet) of the lysosomal membrane that faces the cytoplasm.	got7fsn_ti	external leaflet of lysosomal membrane|external side of lysosomal membrane													cellular_component											owl:Class	
GO:0033641	biolink:NamedThing	modulation by symbiont of host response to pH	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0006061	biolink:NamedThing	sorbitol biosynthetic process	The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.	got7fsn_ti	sorbitol formation|sorbitol synthesis|sorbitol anabolism|sorbitol biosynthesis													biological_process											owl:Class	
GO:0010665	biolink:NamedThing	regulation of cardiac muscle cell apoptotic process	Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	got7fsn_ti	regulation of cardiac muscle cell apoptosis													biological_process											owl:Class	
GO:0106278	biolink:NamedThing	regulation of UDP-N-acetylglucosamine biosynthetic process	Any process that modulates the frequency, rate or extent of the  UDP-N_acetylglucosamine biosynthetic process.	got7fsn_ti	regulation of UDP-GlcNAc biosynthetic process|regulation of UDP-N-acetylglucosamine synthesis|regulation of UDP-N-acetylglucosamine biosynthesis|regulation of UDP-N-acetylglucosamine anabolism|regulation of UDP-N-acetylglucosamine formation						hjd	2020-07-09T17:20:49Z						biological_process											owl:Class	
GO:0032705	biolink:NamedThing	negative regulation of interleukin-21 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production.	got7fsn_ti	down regulation of interleukin-21 production|negative regulation of interleukin-21 biosynthetic process|downregulation of interleukin-21 production|down-regulation of interleukin-21 production										GO:0045391			biological_process											owl:Class	
GO:1900809	biolink:NamedThing	fumigaclavine C biosynthetic process	The chemical reactions and pathways resulting in the formation of fumigaclavine C.	got7fsn_ti	fumigaclavine C anabolism|fumigaclavine C formation|fumigaclavine C biosynthesis|fumigaclavine C synthesis						di	2012-06-04T10:00:06Z						biological_process											owl:Class	
GO:0048350	biolink:NamedThing	positive regulation of paraxial mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification.	got7fsn_ti	stimulation of paraxial mesodermal cell fate specification|activation of paraxial mesodermal cell fate specification|up-regulation of paraxial mesodermal cell fate specification|up regulation of paraxial mesodermal cell fate specification|upregulation of paraxial mesodermal cell fate specification													biological_process											owl:Class	
GO:1902950	biolink:NamedThing	regulation of dendritic spine maintenance	Any process that modulates the frequency, rate or extent of dendritic spine maintenance.	got7fsn_ti							sjp	2014-05-02T08:48:47Z						biological_process											owl:Class	
GO:0072138	biolink:NamedThing	mesenchymal cell proliferation involved in ureteric bud development	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.	got7fsn_ti	ureteric bud mesenchymal cell proliferation						mah	2010-02-22T02:40:38Z						biological_process											owl:Class	
GO:0099551	biolink:NamedThing	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.	got7fsn_ti					Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.									biological_process											owl:Class	
CHEBI:36500	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000710	biolink:NamedThing	negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.	got7fsn_ti	negative regulation of maintenance of centromeric meiotic sister chromatin cohesion|negative regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|negative regulation of maintenance of meiotic sister chromatin cohesion at centromere						mah	2011-06-01T12:41:16Z						biological_process											owl:Class	
GO:1900691	biolink:NamedThing	positive regulation of gliotoxin biosynthetic process	Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process.	got7fsn_ti	activation of gliotoxin biosynthesis|up regulation of gliotoxin biosynthesis|upregulation of gliotoxin biosynthetic process|up-regulation of gliotoxin anabolism|upregulation of gliotoxin synthesis|up regulation of gliotoxin biosynthetic process|positive regulation of gliotoxin biosynthesis|up regulation of gliotoxin synthesis|positive regulation of gliotoxin synthesis|up-regulation of gliotoxin formation|up regulation of gliotoxin anabolism|upregulation of gliotoxin biosynthesis|up-regulation of gliotoxin biosynthetic process|activation of gliotoxin biosynthetic process|positive regulation of gliotoxin formation|activation of gliotoxin formation|activation of gliotoxin anabolism|positive regulation of gliotoxin anabolism|activation of gliotoxin synthesis|upregulation of gliotoxin anabolism|up-regulation of gliotoxin biosynthesis|up-regulation of gliotoxin synthesis|up regulation of gliotoxin formation|upregulation of gliotoxin formation						di	2012-05-22T04:52:08Z						biological_process											owl:Class	
GO:0106111	biolink:NamedThing	regulation of mitotic cohesin ssDNA (lagging strand) loading	Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.	got7fsn_ti							hjd	2018-04-18T14:36:47Z						biological_process											owl:Class	
GO:0044045	biolink:NamedThing	obsolete interaction with host via substance in symbiont cell outer membrane	OBSOLETE. An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that these terms conflate a process and the mechanism of secretion of the compound mediating the process.					True				biological_process											owl:Class	
GO:0110116	biolink:NamedThing	regulation of compound eye photoreceptor cell differentiation	Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation.	got7fsn_ti							kmv	2018-07-16T18:08:49Z						biological_process											owl:Class	
GO:0036370	biolink:NamedThing	D-alanyl carrier activity	Binding a D-alanine and presenting it for processing or offloading to a cognate enzyme. Covalently binds the D-alanine via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into lipoteichoic acid by transferring activated D-alanine to cell membrane phosphatidylglycerol (PG).	got7fsn_ti	D-alanyl carrier protein						bf	2012-10-08T10:30:33Z						molecular_function											owl:Class	
GO:1903966	biolink:NamedThing	monounsaturated fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid.	got7fsn_ti	monounsaturated fatty acid synthesis|monounsaturated fatty acid anabolism|monounsaturated fatty acid formation|monounsaturated fatty acid biosynthesis				For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast.		pr	2015-02-25T20:36:07Z						biological_process											owl:Class	
CHEBI:35369	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060490	biolink:NamedThing	lateral sprouting involved in lung morphogenesis	The process in which a branch forms along the side of the lung epithelial tube.	got7fsn_ti														biological_process											owl:Class	
GO:1904523	biolink:NamedThing	regulation of DNA amplification	Any process that modulates the frequency, rate or extent of DNA amplification.	got7fsn_ti							mcc	2015-07-29T16:24:13Z						biological_process											owl:Class	
GO:1902244	biolink:NamedThing	cis-abienol metabolic process	The chemical reactions and pathways involving cis-abienol.	got7fsn_ti	cis-abienol metabolism						ms	2013-06-20T09:09:51Z						biological_process											owl:Class	
GO:0072467	biolink:NamedThing	obsolete response to cell shape checkpoint signaling	OBSOLETE. A process that occurs in response to signals generated as a result of cell shape checkpoint signaling.	got7fsn_ti	response to signal involved in cell shape checkpoint|cell shape checkpoint effector process				This term was made obsolete because it was ambiguous.		mah	2010-12-09T11:44:11Z		True				biological_process											owl:Class	
GO:0001672	biolink:NamedThing	regulation of chromatin assembly or disassembly	Any process that modulates the frequency, rate or extent of chromatin assembly or disassembly.	got7fsn_ti	regulation of chromatin assembly/disassembly													biological_process											owl:Class	
GO:0008166	biolink:NamedThing	obsolete viral replication	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	viral replication				This term was made obsolete because it covers multiple processes and is now covered by more specific terms.	GO:0019079				True				biological_process											owl:Class	
CHEBI:58243	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019385	biolink:NamedThing	methanogenesis, from acetate	The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate.	got7fsn_ti	methane biosynthesis from acetate|methane biosynthetic process from acetate											MetaCyc:METH-ACETATE-PWY		biological_process											owl:Class	
GO:0030979	biolink:NamedThing	alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.	got7fsn_ti	alpha-glucan anabolism|alpha-glucan biosynthesis|alpha-glucan synthesis|alpha-glucan formation													biological_process											owl:Class	
GO:0001970	biolink:NamedThing	positive regulation of activation of membrane attack complex	Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.	got7fsn_ti	positive regulation of MAC assembly|positive regulation of MAC formation|positive regulation of activation of TCC|positive regulation of activation of the terminal complement cascade|positive regulation of membrane attack complex formation|activation of activation of membrane attack complex|up regulation of activation of membrane attack complex|upregulation of activation of membrane attack complex|positive regulation of membrane attack complex assembly|positive regulation of activation of terminal complement complex|positive regulation of activation of MAC|stimulation of activation of membrane attack complex|up-regulation of activation of membrane attack complex													biological_process											owl:Class	
GO:1901913	biolink:NamedThing	regulation of capsule organization	Any process that modulates the frequency, rate or extent of capsule organization.	got7fsn_ti	regulation of capsule organization and biogenesis|regulation of capsule organisation						di	2013-02-14T06:19:03Z						biological_process											owl:Class	
GO:0032666	biolink:NamedThing	regulation of interleukin-22 production	Any process that modulates the frequency, rate, or extent of interleukin-22 production.	got7fsn_ti	regulation of interleukin-22 biosynthetic process|regulation of IL-22 production										GO:0045393			biological_process											owl:Class	
GO:1900070	biolink:NamedThing	negative regulation of cellular hyperosmotic salinity response	Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response.	got7fsn_ti	inhibition of cellular response to hyperosmotic salt stress|negative regulation of cellular response to hyperosmotic salt stress|down-regulation of cellular hyperosmotic salinity response|downregulation of cellular response to hyperosmotic salt stress|downregulation of cellular hyperosmotic salinity response|down regulation of cellular hyperosmotic salinity response|inhibition of cellular hyperosmotic salinity response|down regulation of cellular response to hyperosmotic salt stress|down-regulation of cellular response to hyperosmotic salt stress						pr	2012-01-26T02:45:43Z						biological_process											owl:Class	
GO:0140394	biolink:NamedThing	ABC-type azole transporter activity	Enables the transfer of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other according to the reaction: ATP + H2O + azole(in) = ADP + phosphate + azole(out).	got7fsn_ti	azole ABC transporter activity|ATPase-coupled azole transmembrane transporter activity						pg	2019-11-28T18:29:48Z				RHEA:33503		molecular_function											owl:Class	
GO:0051440	biolink:NamedThing	obsolete regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle.	got7fsn_ti	meiotic APC regulator|meiotic SCF complex regulator|regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic ubiquitin ligase regulator|meiotic anaphase-promoting complex regulator|regulation of ubiquitin-protein ligase activity during meiotic cell cycle|meiotic ubiquitin-protein ligase regulator	https://github.com/geneontology/go-ontology/issues/15196			This term was obsoleted because it should be captured as a GO-CAM model.					True				biological_process											owl:Class	
GO:1990979	biolink:NamedThing	obsolete copper ion transport across blood-brain barrier	OBSOLETE. The directed movement of copper ions passing through the blood-brain barrier.	got7fsn_ti	copper ion transport across BBB				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-08-17T21:09:08Z		True				biological_process											owl:Class	
GO:0075213	biolink:NamedThing	obsolete negative regulation of transmembrane receptor-mediated cAMP signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1902632	biolink:NamedThing	positive regulation of membrane hyperpolarization	Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization.	got7fsn_ti	up regulation of membrane hyperpolarization|up-regulation of membrane hyperpolarization|activation of membrane hyperpolarization|upregulation of membrane hyperpolarization						krc	2014-01-17T18:28:14Z						biological_process											owl:Class	
GO:0000367	biolink:NamedThing	obsolete second U12-type spliceosomal transesterification activity	OBSOLETE. Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.	got7fsn_ti	second U12-type spliceosomal transesterification activity|3'-splice site cleavage, exon ligation			GO:0000386	This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.					True				molecular_function											owl:Class	
GO:1904802	biolink:NamedThing	RITS complex assembly	The aggregation, arrangement and bonding together of a set of components to form a RITS complex.	got7fsn_ti	RITS complex formation						mah	2015-11-09T16:17:54Z						biological_process											owl:Class	
GO:2000060	biolink:NamedThing	positive regulation of ubiquitin-dependent protein catabolic process	Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process.	got7fsn_ti	positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|positive regulation of protein degradation tagging activity|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitination during ubiquitin-dependent protein degradation|positive regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process						jl	2010-08-20T01:24:03Z						biological_process											owl:Class	
GO:0016341	biolink:NamedThing	obsolete other collagen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	other collagen			GO:0005581	This term was made obsolete because it is a redundant grouping term.					True				cellular_component											owl:Class	
GO:0061199	biolink:NamedThing	striated muscle contraction involved in embryonic body morphogenesis	The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology.	got7fsn_ti							dph	2010-07-28T04:07:23Z						biological_process											owl:Class	
GO:0019491	biolink:NamedThing	ectoine biosynthetic process	The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.	got7fsn_ti	ectoine anabolism|ectoine biosynthesis|ectoine formation|ectoine synthesis											MetaCyc:P101-PWY		biological_process											owl:Class	
GO:0004232	biolink:NamedThing	obsolete interstitial collagenase activity	OBSOLETE. Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue.	got7fsn_ti	interstitial collagenase activity|matrix metalloproteinase 1|MMP-1|vertebrate collagenase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905654	biolink:NamedThing	regulation of artery smooth muscle contraction	Any process that modulates the frequency, rate or extent of artery smooth muscle contraction.	got7fsn_ti							rph	2016-11-09T12:34:46Z						biological_process											owl:Class	
GO:0006634	biolink:NamedThing	hexadecanal biosynthetic process	The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde.	got7fsn_ti	palmitaldehyde biosynthesis|hexadecanal biosynthesis|hexadecanal synthesis|palmitaldehyde biosynthetic process|hexadecanal anabolism|hexadecanal formation													biological_process											owl:Class	
GO:2001293	biolink:NamedThing	malonyl-CoA metabolic process	The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A.	got7fsn_ti	malonyl-CoA metabolism						pr	2012-02-14T02:23:11Z						biological_process											owl:Class	
GO:2000456	biolink:NamedThing	negative regulation of T-helper 17 cell extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation.	got7fsn_ti							bf	2011-03-04T10:50:29Z						biological_process											owl:Class	
GO:0000369	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006503	biolink:NamedThing	obsolete C-terminal protein farnesylation	OBSOLETE. The covalent or non-covalent attachment of a farnesyl group to the carboxy terminus of a protein.	got7fsn_ti	C-terminal protein farnesylation			GO:0018343	This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein.					True				biological_process											owl:Class	
GO:0019404	biolink:NamedThing	galactitol catabolic process	The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	got7fsn_ti	galactitol degradation|galactitol catabolism|galactitol breakdown											MetaCyc:GALACTITOLCAT-PWY		biological_process											owl:Class	
GO:1903850	biolink:NamedThing	regulation of cristae formation	Any process that modulates the frequency, rate or extent of cristae formation.	got7fsn_ti					AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype		pad	2015-01-27T09:42:23Z						biological_process											owl:Class	
GO:2000696	biolink:NamedThing	regulation of epithelial cell differentiation involved in kidney development	Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development.	got7fsn_ti							bf	2011-05-16T04:23:52Z						biological_process											owl:Class	
GO:0031170	biolink:NamedThing	ferricrocin metabolic process	The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.	got7fsn_ti	ferricrocin metabolism													biological_process											owl:Class	
GO:0016536	biolink:NamedThing	obsolete cyclin-dependent protein kinase 5 activator regulator activity	OBSOLETE. Modulation of the activity of cyclin-dependent protein kinase 5 activator.	got7fsn_ti	cyclin-dependent protein kinase 5 activator, intrinsic regulator activity|cyclin-dependent protein kinase 5 activator regulator activity				This term was made obsolete because it refers to a specific gene product.					True				molecular_function											owl:Class	
GO:1900163	biolink:NamedThing	positive regulation of phospholipid scramblase activity	Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity.	got7fsn_ti	up regulation of phospholipid scramblase activity|up-regulation of phospholipid scramblase activity|upregulation of phospholipid scramblase activity|activation of phospholipid scramblase activity						rph	2012-03-08T10:57:26Z						biological_process											owl:Class	
GO:0035048	biolink:NamedThing	obsolete splicing factor protein import into nucleus	OBSOLETE. The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane.	got7fsn_ti	splicing factor protein-nucleus import|splicing factor protein transport from cytoplasm to nucleus				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606				True				biological_process											owl:Class	
GO:0100018	biolink:NamedThing	obsolete regulation of glucose import by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates glucose import.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0032679	biolink:NamedThing	regulation of TRAIL production	Any process that modulates the frequency, rate, or extent of TRAIL production.	got7fsn_ti	regulation of TRAIL biosynthetic process										GO:0045554			biological_process											owl:Class	
GO:0090411	biolink:NamedThing	brassinosteroid binding	Binding to a brassinosteroid.	got7fsn_ti							tb	2011-08-11T02:25:30Z						molecular_function											owl:Class	
GO:1904166	biolink:NamedThing	obsolete negative regulation of cholesterol homeostasis	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol homeostasis.	got7fsn_ti	down-regulation of cholesterol homeostasis|down regulation of cholesterol homeostasis|downregulation of cholesterol homeostasis|inhibition of cholesterol homeostasis				This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2015-04-22T11:11:12Z		True				biological_process											owl:Class	
GO:0009961	biolink:NamedThing	response to 1-aminocyclopropane-1-carboxylic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0042451	biolink:NamedThing	purine nucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	got7fsn_ti	purine nucleoside anabolism|purine nucleoside synthesis|purine nucleoside biosynthesis|purine nucleoside formation													biological_process											owl:Class	
CL:0002543	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902333	biolink:NamedThing	nuclear DNA replication DNA ligation	Any DNA ligation that is involved in nuclear cell cycle DNA replication.	got7fsn_ti	DNA ligation involved in DNA replication during S phase|DNA ligation involved in nuclear cell cycle DNA replication|DNA ligation involved in DNA replication involved in S phase|DNA ligation involved in DNA replication involved in S-phase						jl	2013-07-25T10:55:56Z						biological_process											owl:Class	
GO:0050991	biolink:NamedThing	obsolete enzyme active site formation via O-sulfo-L-threonine	OBSOLETE. The transient sulfation of peptidyl-threonine to form O-sulfo-L-threonine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it was created by error: O-sulfo-L-threonine is a post-translational modification, see PMID:14752058.					True		RESID:AA0362		biological_process											owl:Class	
GO:1904906	biolink:NamedThing	positive regulation of endothelial cell-matrix adhesion via fibronectin	Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.	got7fsn_ti	upregulation of endothelial cell-matrix adhesion via fibronectin|up-regulation of endothelial cell-matrix adhesion via fibronectin|up regulation of endothelial cell-matrix adhesion via fibronectin|activation of endothelial cell-matrix adhesion via fibronectin						bc	2016-01-19T10:23:16Z						biological_process											owl:Class	
GO:0000305	biolink:NamedThing	response to oxygen radical	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.	got7fsn_ti														biological_process											owl:Class	
GO:1905053	biolink:NamedThing	positive regulation of base-excision repair	Any process that activates or increases the frequency, rate or extent of base-excision repair.	got7fsn_ti	positive regulation of BER|upregulation of BER|activation of BER|up-regulation of BER|upregulation of base-excision repair|up-regulation of base-excision repair|up regulation of base-excision repair|up regulation of BER|activation of base-excision repair						ah	2016-03-16T10:52:18Z						biological_process											owl:Class	
GO:0075096	biolink:NamedThing	obsolete modulation by host of symbiont signal transduction mediated by G-protein gamma subunit	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:1901651	biolink:NamedThing	regulation of mitotic chromosome decondensation	Any process that modulates the frequency, rate or extent of mitotic chromosome decondensation.	got7fsn_ti							dph	2012-11-19T14:13:58Z						biological_process											owl:Class	
GO:1902829	biolink:NamedThing	regulation of spinal cord association neuron differentiation	Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation.	got7fsn_ti	regulation of spinal cord dorsal interneuron differentiation						mr	2014-03-31T17:10:55Z						biological_process											owl:Class	
GO:1904782	biolink:NamedThing	negative regulation of NMDA glutamate receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity.	got7fsn_ti	down regulation of N-methyl-D-aspartate selective glutamate receptor activity|downregulation of NMDA receptor|negative regulation of NMDA receptor|down-regulation of NMDA glutamate receptor activity|negative regulation of N-methyl-D-aspartate selective glutamate receptor activity|inhibition of N-methyl-D-aspartate selective glutamate receptor activity|downregulation of NMDA glutamate receptor activity|downregulation of N-methyl-D-aspartate selective glutamate receptor activity|inhibition of NMDA receptor|inhibition of NMDA glutamate receptor activity|down-regulation of NMDA receptor|down-regulation of N-methyl-D-aspartate selective glutamate receptor activity|down regulation of NMDA receptor|down regulation of NMDA glutamate receptor activity						mr	2015-10-30T19:39:31Z						biological_process											owl:Class	
GO:2000415	biolink:NamedThing	positive regulation of fibronectin-dependent thymocyte migration	Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration.	got7fsn_ti	positive regulation of fibronectin-dependent immature T cell migration|positive regulation of fibronectin-dependent immature T-cell migration|positive regulation of fibronectin-dependent thymic lymphocyte migration|positive regulation of fibronectin-dependent immature T lymphocyte migration|positive regulation of fibronectin-dependent immature T-lymphocyte migration						mah	2011-02-23T01:39:00Z						biological_process											owl:Class	
GO:2000165	biolink:NamedThing	regulation of planar cell polarity pathway involved in pericardium morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.	got7fsn_ti							dph	2010-10-05T01:07:36Z						biological_process											owl:Class	
GO:1901066	biolink:NamedThing	syringal lignin biosynthetic process	The chemical reactions and pathways resulting in the formation of syringal lignin.	got7fsn_ti	S-lignin biosynthetic process|syringal lignin formation|syringal lignin synthesis|syringal lignin anabolism|syringal lignin biosynthesis						tt	2012-06-29T03:48:41Z						biological_process											owl:Class	
GO:1902027	biolink:NamedThing	positive regulation of cartilage condensation	Any process that activates or increases the frequency, rate or extent of cartilage condensation.	got7fsn_ti	activation of cartilage condensation|up regulation of cartilage condensation|upregulation of cartilage condensation|up-regulation of cartilage condensation						jl	2013-03-28T17:02:46Z						biological_process											owl:Class	
GO:2000452	biolink:NamedThing	regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.	got7fsn_ti							bf	2011-03-04T10:44:39Z						biological_process											owl:Class	
GO:2000498	biolink:NamedThing	obsolete regulation of induction of apoptosis in response to chemical stimulus	OBSOLETE. Any process that modulates the frequency, rate or extent of induction of apoptosis in response to chemical stimulus.	got7fsn_ti	regulation of induction of apoptosis in response to chemical stimulus|regulation of induction of apoptosis in response to chemical substance				This term was made obsolete because it is ill-defined.		yaf	2011-03-18T02:34:53Z		True				biological_process											owl:Class	
GO:0032916	biolink:NamedThing	positive regulation of transforming growth factor beta3 production	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3.	got7fsn_ti	up-regulation of transforming growth factor-beta3 production|activation of transforming growth factor-beta3 production|stimulation of transforming growth factor-beta3 production|positive regulation of transforming growth factor-beta3 production|positive regulation of TGFB3 production|positive regulation of TGF-B3 production|up regulation of transforming growth factor-beta3 production|upregulation of transforming growth factor-beta3 production													biological_process											owl:Class	
GO:0060824	biolink:NamedThing	retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate.	got7fsn_ti	retinoic acid receptor signalling pathway involved in neural plate anterior/posterior pattern formation						dph	2009-08-11T01:30:57Z						biological_process											owl:Class	
CHEBI:28885	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140482	biolink:NamedThing	iron sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of iron.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19433					pg	2020-06-25T20:58:02Z						molecular_function											owl:Class	
GO:0048035	biolink:NamedThing	heme o catabolic process	The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.	got7fsn_ti	heme o degradation|heme o breakdown|haem o catabolism|heme o catabolism|haem o catabolic process													biological_process											owl:Class	
GO:2001313	biolink:NamedThing	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process	The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.	got7fsn_ti	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolism						pr	2012-03-22T01:19:54Z						biological_process											owl:Class	
GO:1901560	biolink:NamedThing	response to purvalanol A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.	got7fsn_ti							mah	2012-11-02T15:32:28Z						biological_process											owl:Class	
GO:0034140	biolink:NamedThing	negative regulation of toll-like receptor 3 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.	got7fsn_ti	negative regulation of TLR3 signaling pathway|negative regulation of toll-like receptor 3 signalling pathway													biological_process											owl:Class	
GO:0062234	biolink:NamedThing	platelet activating factor catabolic process	The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine.	got7fsn_ti	2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine catabolic process|PAF catabolic process						dph	2020-03-23T15:35:49Z						biological_process											owl:Class	
GO:0099112	biolink:NamedThing	microtubule polymerization based protein transport	The transport of a protein driven by polymerization of a microtubule to which it is attached.	got7fsn_ti														biological_process											owl:Class	
GO:1900913	biolink:NamedThing	positive regulation of olefin biosynthetic process	Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process.	got7fsn_ti	activation of olefin anabolism|positive regulation of olefin biosynthesis|upregulation of olefin biosynthesis|upregulation of olefin formation|activation of olefin formation|positive regulation of olefin anabolism|positive regulation of olefin formation|up-regulation of olefin synthesis|activation of olefin biosynthesis|up-regulation of olefin anabolism|up regulation of olefin anabolism|upregulation of olefin anabolism|up-regulation of olefin biosynthetic process|positive regulation of olefin synthesis|upregulation of olefin synthesis|up-regulation of olefin formation|up-regulation of olefin biosynthesis|activation of olefin synthesis|up regulation of olefin biosynthetic process|upregulation of olefin biosynthetic process|up regulation of olefin formation|up regulation of olefin synthesis|up regulation of olefin biosynthesis|activation of olefin biosynthetic process						tt	2012-06-13T04:20:38Z						biological_process											owl:Class	
GO:2001145	biolink:NamedThing	negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.	got7fsn_ti							yaf	2011-10-19T10:41:28Z						biological_process											owl:Class	
GO:0002709	biolink:NamedThing	regulation of T cell mediated immunity	Any process that modulates the frequency, rate, or extent of T cell mediated immunity.	got7fsn_ti	regulation of T-cell mediated immunity|regulation of T-lymphocyte mediated immunity|regulation of T lymphocyte mediated immunity													biological_process											owl:Class	
GO:0070894	biolink:NamedThing	regulation of transposon integration	Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.	got7fsn_ti							mah	2009-09-01T04:14:09Z						biological_process											owl:Class	
GO:0000174	biolink:NamedThing	obsolete inactivation of MAPK (mating sensu Saccharomyces)	OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.	got7fsn_ti	inactivation of MAPK (mating sensu Saccharomyces)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
UBERON:0000045	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902017	biolink:NamedThing	regulation of cilium assembly	Any process that modulates the frequency, rate or extent of cilium assembly.	got7fsn_ti	regulation of ciliogenesis|regulation of cilium biogenesis						dph	2013-03-26T18:10:51Z						biological_process											owl:Class	
GO:1901392	biolink:NamedThing	regulation of transforming growth factor beta1 activation	Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation.	got7fsn_ti	regulation of TGFbeta 1 activation|regulation of TGFB1 activation|regulation of latent-TGF-beta1 activation|regulation of transforming growth factor-beta1 activation|regulation of L-TGF-beta 1 activation|regulation of TGF-beta 1 activation						bf	2012-10-01T10:40:06Z						biological_process											owl:Class	
GO:0062098	biolink:NamedThing	regulation of programmed necrotic cell death	Any process that modulates the frequency, rate or extent of programmed necrotic cell death.	got7fsn_ti							dph	2018-11-29T14:58:26Z						biological_process											owl:Class	
GO:2000308	biolink:NamedThing	negative regulation of tumor necrosis factor (ligand) superfamily member 11 production	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.	got7fsn_ti	negative regulation of TNFSF11 production|negative regulation of RANKL production						mah	2011-01-17T10:44:33Z						biological_process											owl:Class	
GO:0052379	biolink:NamedThing	obsolete modulation by organism of entry into other organism via phagocytosis involved in symbiotic interaction	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent to which it enters into a second organism via the phagocytotic processes of the other organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation by organism of entry into other organism via phagocytosis during symbiotic interaction|modulation by organism of entry into other organism via other organism phagocytosis during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18562			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0045205	biolink:NamedThing	obsolete MAPK transporter activity	OBSOLETE. Enables the directed movement of MAP kinase into, out of or within a cell, or between cells.	got7fsn_ti	MAPK transporter activity				This term was made obsolete because we do not know what it was intended to represent when it was created.					True				molecular_function											owl:Class	
GO:0002840	biolink:NamedThing	regulation of T cell mediated immune response to tumor cell	Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell.	got7fsn_ti	regulation of T-cell mediated immune response to tumor cell|regulation of T lymphocyte mediated immune response to tumor cell|regulation of T cell mediated immune response to tumour cell|regulation of T-lymphocyte mediated immune response to tumor cell													biological_process											owl:Class	
GO:0006062	biolink:NamedThing	sorbitol catabolic process	The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.	got7fsn_ti	sorbitol breakdown|sorbitol catabolism|sorbitol degradation											MetaCyc:SORBDEG-PWY		biological_process											owl:Class	
GO:2000225	biolink:NamedThing	negative regulation of testosterone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process.	got7fsn_ti							yaf	2010-11-09T10:38:37Z						biological_process											owl:Class	
GO:1902265	biolink:NamedThing	abscisic acid homeostasis	Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell.	got7fsn_ti	ABA homeostasis|2-cis-abscisate homeostasis						tb	2013-06-27T21:05:30Z						biological_process											owl:Class	
GO:0070881	biolink:NamedThing	regulation of proline transport	Any process that modulates the frequency, rate or extent of proline transport.	got7fsn_ti							mah	2009-08-21T04:48:34Z						biological_process											owl:Class	
GO:0017107	biolink:NamedThing	obsolete anion exchanger adaptor activity	OBSOLETE. The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way.	got7fsn_ti					The term was made obsolete because it referred to an interaction of an anion transporter with the AP1 adaptor by which it is probably transported, see: PMID:22744004; PMID:20833140; ie the adaptor does not specifically target an anion adaptor.					True				molecular_function											owl:Class	
GO:2001242	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.	got7fsn_ti	regulation of mitochondrial-mediated apoptotic pathway|regulation of intrinsic apoptotic pathway|regulation of intrinsic apoptosis|regulation of intrinsic apoptotic signalling pathway						pr	2011-11-24T01:35:56Z						biological_process											owl:Class	
GO:0050517	biolink:NamedThing	obsolete inositol hexakisphosphate kinase activity	OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate, and ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).	got7fsn_ti	ATP:1D-myo-inositol-hexakisphosphate phosphotransferase activity|inositol-hexakisphosphate kinase activity|inositol hexakisphosphate kinase activity|ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity				Note that this was EC:2.7.1.152. This term was made obsolete because this activity is currently defined as catalyzing two reactions based on a gene product. The reactions listed in the definition can be catalyzed independently by other gene products.					True		EC:2.7.4.21|MetaCyc:2.7.1.152-RXN		molecular_function											owl:Class	
GO:0060376	biolink:NamedThing	positive regulation of mast cell differentiation	Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	got7fsn_ti														biological_process											owl:Class	
UBERON:0009050	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001112	biolink:NamedThing	regulation of cellular response to hepatocyte growth factor stimulus	Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.	got7fsn_ti	regulation of cellular response to HGF stimulus						dph	2011-10-05T05:43:18Z						biological_process											owl:Class	
GO:0006738	biolink:NamedThing	nicotinamide riboside catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.	got7fsn_ti	nicotinamide riboside breakdown|N-ribosylnicotinamide catabolic process|nicotinamide riboside degradation|nicotinamide riboside catabolism													biological_process											owl:Class	
GO:0005038	biolink:NamedThing	obsolete death receptor interacting protein activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	death receptor interacting protein activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005123|GO:0005515				True				molecular_function											owl:Class	
GO:1905771	biolink:NamedThing	negative regulation of mesodermal cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation.	got7fsn_ti	downregulation of mesodermal cell differentiation|down-regulation of mesodermal cell differentiation|down-regulation of mesoderm cell differentiation|inhibition of mesodermal cell differentiation|inhibition of mesoderm cell differentiation|down regulation of mesodermal cell differentiation|down regulation of mesoderm cell differentiation|negative regulation of mesoderm cell differentiation|downregulation of mesoderm cell differentiation						rph	2016-12-21T12:44:23Z						biological_process											owl:Class	
GO:0060237	biolink:NamedThing	regulation of fungal-type cell wall organization	Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.	got7fsn_ti	regulation of fungal-type cell wall organization and biogenesis|regulation of fungal-type cell wall organisation													biological_process											owl:Class	
GO:1901918	biolink:NamedThing	negative regulation of exoribonuclease activity	Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity.	got7fsn_ti	downregulation of exoribonuclease activity|down regulation of exoribonuclease activity|down-regulation of exoribonuclease activity|inhibition of exoribonuclease activity						rb	2013-02-15T00:58:03Z						biological_process											owl:Class	
GO:0006848	biolink:NamedThing	pyruvate transport	The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1901501	biolink:NamedThing	response to xylene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus.	got7fsn_ti							tt	2012-10-16T15:25:47Z						biological_process											owl:Class	
GO:0015002	biolink:NamedThing	obsolete heme-copper terminal oxidase activity	OBSOLETE. Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane.	got7fsn_ti	haem-copper terminal oxidase activity	https://github.com/geneontology/go-ontology/issues/20924			This term was obsoleted because it groups the last enzymes in the electron transport chain, and is not an appropriate grouping term for molecular function.					True				molecular_function											owl:Class	
GO:0060196	biolink:NamedThing	positive regulation of antisense RNA transcription	Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.	got7fsn_ti														biological_process											owl:Class	
GO:2001260	biolink:NamedThing	regulation of semaphorin-plexin signaling pathway	Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway.	got7fsn_ti	regulation of semaphorin-plexin signalling pathway						vk	2011-12-08T02:05:41Z						biological_process											owl:Class	
UBERON:0001727	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902967	biolink:NamedThing	protein localization to mitotic spindle midzone	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone.	got7fsn_ti	protein localisation in mitotic spindle midzone|protein localization in mitotic spindle midzone|protein localisation to mitotic spindle midzone						mah	2014-05-06T14:40:01Z						biological_process											owl:Class	
CHEBI:22385	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901354	biolink:NamedThing	response to L-canavanine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus.	got7fsn_ti							mah	2012-09-13T13:11:17Z						biological_process											owl:Class	
GO:1902318	biolink:NamedThing	synthesis of RNA primer involved in nuclear cell cycle DNA replication	Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication.	got7fsn_ti	replication priming involved in nuclear cell cycle DNA replication|replication priming involved in DNA replication involved in S-phase|replication priming involved in DNA replication involved in S phase|DNA replication, synthesis of RNA primer involved in DNA replication involved in S phase|replication priming involved in DNA replication during S phase|DNA replication, synthesis of RNA primer involved in DNA replication involved in S-phase|DNA replication, synthesis of RNA primer involved in DNA replication during S phase						jl	2013-07-23T14:00:33Z						biological_process											owl:Class	
GO:0033507	biolink:NamedThing	glucosinolate biosynthetic process from phenylalanine	The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine.	got7fsn_ti	glucosinolate formation from phenylalanine|glucosinolate biosynthesis from phenylalanine|glucosinolate synthesis from phenylalanine|glucosinolate anabolism from phenylalanine											MetaCyc:PWY-2821		biological_process											owl:Class	
GO:0061913	biolink:NamedThing	positive regulation of growth plate cartilage chondrocyte proliferation	Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.	got7fsn_ti							dph	2017-07-10T17:31:09Z						biological_process											owl:Class	
GO:0019793	biolink:NamedThing	obsolete ISG15 carrier activity	OBSOLETE. Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other.	got7fsn_ti	interferon-stimulated gene-15 carrier activity|ISG15 carrier activity				This term was made obsolete because it is gene product-specific.					True				molecular_function											owl:Class	
UBERON:0000984	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098550	biolink:NamedThing	lumenal side of early endosome membrane	The side (leaflet) of the early endosome membrane that faces the lumen.	got7fsn_ti	internal side of early endosome membrane|internal leaflet of early endosome membrane													cellular_component											owl:Class	
GO:0016126	biolink:NamedThing	sterol biosynthetic process	The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti	sterol synthesis|sterol formation|sterol anabolism|sterol biosynthesis											MetaCyc:PWY-2541		biological_process											owl:Class	
GO:0010571	biolink:NamedThing	positive regulation of nuclear cell cycle DNA replication	Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.	got7fsn_ti	positive regulation of DNA replication during S phase|positive regulation of DNA replication involved in S-phase|positive regulation of DNA replication involved in S phase													biological_process											owl:Class	
OBO:OBA_0000018	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035332	biolink:NamedThing	positive regulation of hippo signaling	Any process that activates or increases the frequency, rate or extent of hippo signaling.	got7fsn_ti	positive regulation of hippo signaling pathway|positive regulation of hippo signaling cascade|positive regulation of hippo signalling cascade						bf	2010-02-26T10:54:59Z						biological_process											owl:Class	
GO:2001130	biolink:NamedThing	methane biosynthetic process from trimethylamine	The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine.	got7fsn_ti							jl	2011-10-13T10:28:03Z						biological_process											owl:Class	
GO:0060647	biolink:NamedThing	mesenchymal cell condensation involved in mammary fat development	The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.	got7fsn_ti							dph	2009-05-29T08:33:29Z						biological_process											owl:Class	
GO:1902888	biolink:NamedThing	protein localization to astral microtubule	A process in which a protein is transported to, or maintained in, a location within an astral microtubule.	got7fsn_ti	protein localization in astral microtubule|protein localisation to astral microtubule|protein localisation in astral microtubule						kmv	2014-04-05T21:26:34Z						biological_process											owl:Class	
GO:1901563	biolink:NamedThing	response to camptothecin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.	got7fsn_ti	response to CPT						mah	2012-11-02T15:32:45Z						biological_process											owl:Class	
GO:0042103	biolink:NamedThing	positive regulation of T cell homeostatic proliferation	Any process that activates or increases the rate or extent of resting T cell proliferation.	got7fsn_ti	stimulation of T cell homeostatic proliferation|positive regulation of T-lymphocyte homeostatic proliferation|positive regulation of T lymphocyte homeostatic proliferation|up regulation of T cell homeostatic proliferation|up-regulation of T cell homeostatic proliferation|upregulation of T cell homeostatic proliferation|activation of T cell homeostatic proliferation|positive regulation of T-cell homeostatic proliferation|positive regulation of resting T cell proliferation													biological_process											owl:Class	
GO:1903718	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044439	biolink:NamedThing	obsolete peroxisomal part	OBSOLETE. Any constituent part of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2).	got7fsn_ti	peroxisome component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005777				True				cellular_component											owl:Class	
GO:2000221	biolink:NamedThing	negative regulation of pseudohyphal growth	Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.	got7fsn_ti							mah	2010-11-03T04:37:00Z						biological_process											owl:Class	
GO:0002892	biolink:NamedThing	regulation of type II hypersensitivity	Any process that modulates the frequency, rate, or extent of type II hypersensitivity.	got7fsn_ti														biological_process											owl:Class	
GO:1900899	biolink:NamedThing	regulation of heptadecane metabolic process	Any process that modulates the frequency, rate or extent of heptadecane metabolic process.	got7fsn_ti	regulation of heptadecane metabolism						tt	2012-06-13T03:30:03Z						biological_process											owl:Class	
GO:1902946	biolink:NamedThing	protein localization to early endosome	A process in which a protein is transported to, or maintained in, a location within an early endosome.	got7fsn_ti	protein localization in early endosome|protein localisation in early endosome|protein localisation to early endosome						sjp	2014-05-02T08:26:00Z						biological_process											owl:Class	
GO:1901916	biolink:NamedThing	obsolete protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis	OBSOLETE. Any protein kinase activity that is involved in regulation of protein localization to cell division site involved in cytokinesis.	got7fsn_ti	protein kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis|protamine kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis|protamine kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis	https://github.com/geneontology/go-ontology/issues/20226			This term was obsoleted is that this term represents both a function and a process.		dph	2013-02-14T15:30:37Z		True				molecular_function											owl:Class	
GO:1904574	biolink:NamedThing	negative regulation of selenocysteine insertion sequence binding	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding.	got7fsn_ti	downregulation of SECIS binding|down-regulation of selenocysteine insertion sequence binding|inhibition of SECIS binding|down regulation of SECIS binding|downregulation of selenocysteine insertion sequence binding|down-regulation of SECIS binding|inhibition of selenocysteine insertion sequence binding|down regulation of selenocysteine insertion sequence binding|negative regulation of SECIS binding						sl	2015-08-19T17:51:15Z						biological_process											owl:Class	
GO:0072709	biolink:NamedThing	cellular response to sorbitol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.	got7fsn_ti	cellular response to glucitol						mah	2012-04-11T03:41:03Z						biological_process											owl:Class	
GO:0090202	biolink:NamedThing	obsolete gene looping	OBSOLETE. The formation and maintenance of DNA loops that juxtapose sequentially separated regions of RNA polymerase II-transcribed genes.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20204			This term was obsoleted because it was defined like a molecular function.	GO:0140587	tb	2009-12-18T11:56:00Z		True				biological_process											owl:Class	
GO:1902169	biolink:NamedThing	cellular response to catechin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.	got7fsn_ti							rjd	2013-05-22T17:35:40Z						biological_process											owl:Class	
GO:0046307	biolink:NamedThing	Z-phenylacetaldoxime biosynthetic process	The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.	got7fsn_ti	Z-phenylacetaldoxime formation|Z-phenylacetaldoxime anabolism|Z-phenylacetaldoxime biosynthesis|Z-phenylacetaldoxime synthesis													biological_process											owl:Class	
GO:0051537	biolink:NamedThing	2 iron, 2 sulfur cluster binding	Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.	got7fsn_ti	diiron disulfide cluster binding|iron-sulfur cluster 2Fe-2S binding|2Fe-2S cluster binding|diiron disulphide cluster binding|2 Fe 2 S cluster binding|2 iron, 2 sulphur cluster binding|iron-sulphur cluster 2Fe-2S binding													molecular_function											owl:Class	
GO:1901870	biolink:NamedThing	ecgonone methyl ester metabolic process	The chemical reactions and pathways involving ecgonone methyl ester.	got7fsn_ti	ecgonone methyl ester metabolism						ms	2013-02-04T11:58:30Z						biological_process											owl:Class	
GO:0055055	biolink:NamedThing	D-glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose.	got7fsn_ti	D-glucose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0042301	biolink:NamedThing	phosphate ion binding	Binding to a phosphate ion.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:9168	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004249	biolink:NamedThing	obsolete stromelysin 3 activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	matrix metalloproteinase 11|stromelysin 3 activity|MMP-11			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:61297	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000003761	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903688	biolink:NamedThing	positive regulation of border follicle cell migration	Any process that activates or increases the frequency, rate or extent of border follicle cell migration.	got7fsn_ti	activation of border follicle cell migration						als	2014-12-01T13:41:19Z						biological_process											owl:Class	
GO:0045583	biolink:NamedThing	regulation of cytotoxic T cell differentiation	Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation.	got7fsn_ti	regulation of cytotoxic T lymphocyte differentiation|regulation of cytotoxic T cell development|regulation of cytotoxic T-cell differentiation|regulation of cytotoxic T-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0032554	biolink:NamedThing	purine deoxyribonucleotide binding	Binding to a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	got7fsn_ti														molecular_function											owl:Class	
GO:0010528	biolink:NamedThing	regulation of transposition	Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.	got7fsn_ti														biological_process											owl:Class	
GO:1904133	biolink:NamedThing	regulation of convergent extension involved in rhombomere morphogenesis	Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.	got7fsn_ti							dph	2015-04-10T21:21:12Z						biological_process											owl:Class	
GO:0008822	biolink:NamedThing	obsolete crotonobetaine/carnitine-CoA ligase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	crotonobetaine/carnitine-CoA ligase activity				This term was made obsolete because it represents a bifunctional gene product.	GO:0051108|GO:0051109				True				molecular_function											owl:Class	
GO:0106159	biolink:NamedThing	regulation of small RNA loading onto RISC	Any process that modulates the frequency, rate or extent small RNA loading onto RISC.	got7fsn_ti							hjd	2018-11-30T15:38:50Z						biological_process											owl:Class	
GO:0035416	biolink:NamedThing	obsolete positive regulation of mitotic prometaphase	OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.	got7fsn_ti	positive regulation of mitotic prometaphase				This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		bf	2010-03-29T10:52:55Z		True				biological_process											owl:Class	
GO:0048387	biolink:NamedThing	negative regulation of retinoic acid receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.	got7fsn_ti	downregulation of retinoic acid receptor signaling pathway|negative regulation of RAR signalling pathway|down regulation of retinoic acid receptor signaling pathway|negative regulation of RAR signaling pathway|inhibition of retinoic acid receptor signaling pathway|down-regulation of retinoic acid receptor signaling pathway|negative regulation of retinoic acid receptor signalling pathway													biological_process											owl:Class	
CHEBI:25450	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900387	biolink:NamedThing	obsolete negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		pr	2012-04-18T12:01:19Z		True				biological_process											owl:Class	
GO:0034118	biolink:NamedThing	regulation of erythrocyte aggregation	Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.	got7fsn_ti	regulation of RBC aggregation|regulation of red blood cell aggregation													biological_process											owl:Class	
GO:0032830	biolink:NamedThing	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.	got7fsn_ti	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0007090	biolink:NamedThing	obsolete regulation of S phase of mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle.	got7fsn_ti	regulation of S-phase of mitotic cell cycle|regulation of S phase of mitotic cell cycle				This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.	GO:0044772				True				biological_process											owl:Class	
GO:0003797	biolink:NamedThing	obsolete antibacterial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells.	got7fsn_ti	antibacterial peptide activity				This term was made obsolete because it describes involvement in a process and not a function.	GO:0042742				True				molecular_function											owl:Class	
GO:0071519	biolink:NamedThing	actomyosin contractile ring actin filament bundle assembly	A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis.	got7fsn_ti	actin filament bundle assembly involved in actomyosin contractile ring formation|actin filament bundle assembly involved in cytokinetic actomyosin contractile ring assembly						mah	2010-01-06T05:27:59Z						biological_process											owl:Class	
GO:0075253	biolink:NamedThing	positive regulation of uredospore formation	Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.	got7fsn_ti	positive regulation of ureidospore formation													biological_process											owl:Class	
GO:0007002	biolink:NamedThing	obsolete centromere binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	centromere binding			GO:0019237	This term was made obsolete because it represents a molecular function and not a biological process.					True				biological_process											owl:Class	
GO:1904652	biolink:NamedThing	protein localization to cell division site involved in cell separation after cytokinesis	Any protein localization to cell division site that is involved in cell separation after cytokinesis.	got7fsn_ti							vw	2015-09-01T21:04:45Z						biological_process											owl:Class	
GO:0097333	biolink:NamedThing	response to olanzapine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.	got7fsn_ti							pr	2012-06-12T11:00:04Z						biological_process											owl:Class	
GO:2000950	biolink:NamedThing	positive regulation of xyloglucan metabolic process	Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process.	got7fsn_ti	positive regulation of xyloglucan metabolism						tt	2011-08-01T02:17:02Z						biological_process											owl:Class	
GO:0014026	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007241	biolink:NamedThing	obsolete inactivation of Hog1	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	inactivation of Hog1				This term was made obsolete because it contains gene product and species specific information.					True				biological_process											owl:Class	
UBERON:0001756	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043848	biolink:NamedThing	obsolete excinuclease cho activity	OBSOLETE. Catalysis of the incision of damaged DNA on the 3' side of a lesion, typically at the ninth phosphodiester bond 3' of the damage.	got7fsn_ti	cho|uvrc homolog protein|endonuclease cho				This term was obsoleted because it represented a gene product.					True				molecular_function											owl:Class	
GO:0015340	biolink:NamedThing	obsolete zinc, cadmium uptake permease activity	OBSOLETE. Catalysis of the reaction: (Zn2+ or Cd2+)(out) = (Zn2+ or Cd2+)(in). The activity is driven by proton motive force, possibly by proton symport.	got7fsn_ti	zinc, cadmium uptake permease activity				This term was made obsolete because it represents more than one molecular function.	GO:0005385|GO:0015086				True				molecular_function											owl:Class	
CL:0000448	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002258	biolink:NamedThing	positive regulation of kinin cascade	Any process that activates or increases the frequency, rate, or extent of the kinin cascade.	got7fsn_ti	up regulation of kinin cascade|up-regulation of kinin cascade|upregulation of kinin cascade|activation of kinin cascade|stimulation of kinin cascade													biological_process											owl:Class	
GO:1900427	biolink:NamedThing	obsolete regulation of cellular response to oxidative stress by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cellular response to oxidative stress.	got7fsn_ti	regulation of adaptive response to oxidative stress by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-25T09:11:41Z		True				biological_process											owl:Class	
GO:1901323	biolink:NamedThing	response to erythromycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.	got7fsn_ti							mah	2012-08-30T10:09:59Z						biological_process											owl:Class	
GO:0030441	biolink:NamedThing	obsolete activation of MAPKKK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of MAPKKK during sporulation (sensu Fungi)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:1902720	biolink:NamedThing	obsolete intracellular sequestering of copper ion	OBSOLETE. The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.	got7fsn_ti	intracellular sequestering of copper ion				This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2014-02-24T16:09:18Z		True				biological_process											owl:Class	
GO:1903831	biolink:NamedThing	signal transduction involved in cellular response to ammonium ion	Any signal transduction that is involved in cellular response to ammonium ion.	got7fsn_ti	signalling pathway involved in cellular response to ammonium ion|signalling cascade involved in cellular response to ammonium ion|signaling pathway involved in cellular response to ammonium ion|signaling cascade involved in cellular response to ammonium ion						al	2015-01-21T17:52:09Z						biological_process											owl:Class	
CHEBI:57947	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903446	biolink:NamedThing	geraniol metabolic process	The chemical reactions and pathways involving geraniol.	got7fsn_ti	geraniol metabolism						di	2014-09-19T08:18:34Z						biological_process											owl:Class	
GO:0003412	biolink:NamedThing	establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis	The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye.	got7fsn_ti							dph	2009-12-21T03:09:23Z						biological_process											owl:Class	
CHEBI:22720	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903112	biolink:NamedThing	positive regulation of single-strand break repair via homologous recombination	Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination.	got7fsn_ti	up regulation of single-strand break repair via homologous recombination|up-regulation of single-strand break repair via homologous recombination|upregulation of single-strand break repair via homologous recombination|activation of single-strand break repair via homologous recombination						pr	2014-06-09T12:11:38Z						biological_process											owl:Class	
GO:0099184	biolink:NamedThing	structural constituent of postsynaptic intermediate filament cytoskeleton	The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton.	got7fsn_ti							dos	2017-12-20T13:45:35Z						molecular_function											owl:Class	
GO:1904998	biolink:NamedThing	negative regulation of leukocyte adhesion to arterial endothelial cell	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.	got7fsn_ti	down regulation of leukocyte adhesion to arterial endothelial cell|down-regulation of leukocyte adhesion to arterial endothelial cell|downregulation of leukocyte adhesion to arterial endothelial cell|inhibition of leukocyte adhesion to arterial endothelial cell						bc	2016-03-01T11:04:57Z						biological_process											owl:Class	
GO:0090335	biolink:NamedThing	regulation of brown fat cell differentiation	Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.	got7fsn_ti							tb	2010-06-01T03:16:57Z						biological_process											owl:Class	
GO:0033360	biolink:NamedThing	lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate	The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.	got7fsn_ti	lysine biosynthetic process via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate|lysine synthesis via diaminopimelate and L-2-acetamido-6-oxoheptanedioate|lysine biosynthesis via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate|lysine anabolism via diaminopimelate and L-2-acetamido-6-oxoheptanedioate|lysine formation via diaminopimelate and L-2-acetamido-6-oxoheptanedioate											MetaCyc:PWY-2941		biological_process											owl:Class	
GO:0005487	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905215	biolink:NamedThing	negative regulation of RNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding.	got7fsn_ti	down regulation of RNA binding|downregulation of RNA binding|inhibition of RNA binding|down-regulation of RNA binding						bf	2016-06-06T10:21:04Z						biological_process											owl:Class	
GO:0001082	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase I transcription factor binding	OBSOLETE. Binding to an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	RNA polymerase I transcription factor binding transcription factor activity				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2010-10-27T04:03:47Z		True				molecular_function											owl:Class	
GO:2000881	biolink:NamedThing	regulation of starch catabolic process	Any process that modulates the frequency, rate or extent of starch catabolic process.	got7fsn_ti	regulation of starch breakdown|regulation of starch catabolism|regulation of starch degradation						bf	2011-07-27T03:23:39Z						biological_process											owl:Class	
GO:0045848	biolink:NamedThing	positive regulation of nitrogen utilization	Any process that activates or increases the frequency, rate or extent of nitrogen utilization.	got7fsn_ti	up regulation of nitrogen utilization|upregulation of nitrogen utilization|activation of nitrogen utilization|stimulation of nitrogen utilization|up-regulation of nitrogen utilization													biological_process											owl:Class	
GO:0032822	biolink:NamedThing	positive regulation of natural killer cell proliferation involved in immune response	Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response.	got7fsn_ti	positive regulation of natural killer cell proliferation during immune response|stimulation of natural killer cell proliferation during immune response|positive regulation of NK cell proliferation during immune response|upregulation of natural killer cell proliferation during immune response|activation of natural killer cell proliferation during immune response|up-regulation of natural killer cell proliferation during immune response|up regulation of natural killer cell proliferation during immune response													biological_process											owl:Class	
GO:0045747	biolink:NamedThing	positive regulation of Notch signaling pathway	Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.	got7fsn_ti	stimulation of Notch signaling pathway|upregulation of Notch signaling pathway|positive regulation of N signaling pathway|activation of Notch signaling pathway|up-regulation of Notch signaling pathway|positive regulation of N signalling pathway|up regulation of Notch signaling pathway|positive regulation of Notch signalling pathway													biological_process											owl:Class	
GO:1903380	biolink:NamedThing	positive regulation of mitotic chromosome condensation	Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.	got7fsn_ti	up regulation of mitotic chromosome condensation|activation of mitotic chromosome condensation|up-regulation of mitotic chromosome condensation|upregulation of mitotic chromosome condensation						al	2014-08-26T13:57:29Z						biological_process											owl:Class	
GO:0085008	biolink:NamedThing	obsolete interaction with host via secreted substance released from microneme	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the microneme, a small, elongated secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:03:16Z		True				biological_process											owl:Class	
GO:0015000	biolink:NamedThing	obsolete polyferredoxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	polyferredoxin			GO:0009055	This term was made obsolete because it does not represent a function.					True				molecular_function											owl:Class	
GO:0018804	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001658	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075022	biolink:NamedThing	obsolete ethylene-mediated activation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0080093	biolink:NamedThing	regulation of photorespiration	Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved.	got7fsn_ti							dhl	2009-04-22T04:44:48Z						biological_process											owl:Class	
GO:1904815	biolink:NamedThing	negative regulation of protein localization to chromosome, telomeric region	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region.	got7fsn_ti	downregulation of protein localization to chromosome, telomeric region|inhibition of protein localization to chromosome, telomeric region|down regulation of protein localization to chromosome, telomeric region|inhibition of protein localization to telomere|downregulation of protein localisation to chromosome, telomeric region|down-regulation of protein localisation to chromosome, telomeric region|down-regulation of protein localization to chromosome, telomeric region|down regulation of protein localisation to chromosome, telomeric region|inhibition of protein localisation to chromosome, telomeric region|down-regulation of protein localization to telomere|negative regulation of protein localisation to chromosome, telomeric region|downregulation of protein localization to telomere|negative regulation of protein localization to telomere|down regulation of protein localization to telomere						nc	2015-11-16T12:18:51Z						biological_process											owl:Class	
GO:0032669	biolink:NamedThing	regulation of interleukin-25 production	Any process that modulates the frequency, rate, or extent of interleukin-25 production.	got7fsn_ti	regulation of interleukin-25 secretion|regulation of IL-25 production|regulation of interleukin-25 biosynthetic process						bc	2019-12-09T16:51:07Z			GO:0150148|GO:0045529			biological_process											owl:Class	
GO:2000428	biolink:NamedThing	regulation of neutrophil aggregation	Any process that modulates the frequency, rate or extent of neutrophil aggregation.	got7fsn_ti	regulation of neutrophil leucocyte aggregation|regulation of neutrocyte aggregation|regulation of neutrophilic leukocyte aggregation						ebc	2011-02-28T05:18:54Z						biological_process											owl:Class	
GO:0052318	biolink:NamedThing	regulation of phytoalexin metabolic process	Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.	got7fsn_ti	regulation of phytoalexin metabolism													biological_process											owl:Class	
GO:0001689	biolink:NamedThing	obsolete cytoplasmic dynein intermediate light chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytoplasmic dynein intermediate light chain			GO:0005868	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:0030811	biolink:NamedThing	regulation of nucleotide catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.	got7fsn_ti	regulation of nucleotide catabolism|regulation of nucleotide breakdown|regulation of nucleotide degradation													biological_process											owl:Class	
GO:0035897	biolink:NamedThing	obsolete proteolysis in other organism	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.		bf	2011-06-15T03:00:27Z		True				biological_process											owl:Class	
GO:0030955	biolink:NamedThing	potassium ion binding	Binding to a potassium ion (K+).	got7fsn_ti	K ion binding													molecular_function											owl:Class	
GO:1905844	biolink:NamedThing	negative regulation of cellular response to gamma radiation	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation.	got7fsn_ti	down-regulation of cellular response to gamma-ray photon|negative regulation of cellular response to gamma-ray photon|downregulation of cellular response to gamma ray|down-regulation of cellular response to gamma ray|inhibition of cellular response to gamma-ray photon|downregulation of cellular response to gamma-ray photon|down regulation of cellular response to gamma radiation|down regulation of cellular response to gamma ray|down-regulation of cellular response to gamma radiation|negative regulation of cellular response to gamma ray|inhibition of cellular response to gamma ray|down regulation of cellular response to gamma-ray photon|inhibition of cellular response to gamma radiation|downregulation of cellular response to gamma radiation						rz	2017-01-19T10:24:48Z						biological_process											owl:Class	
GO:1904279	biolink:NamedThing	regulation of transcription by RNA polymerase V	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V.	got7fsn_ti	regulation of transcription from RNA polymerase V promoter|regulation of transcription from RNA pol V promoter						tb	2015-06-03T22:01:47Z						biological_process											owl:Class	
GO:0071893	biolink:NamedThing	BMP signaling pathway involved in nephric duct formation	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to nephric duct formation.	got7fsn_ti	BMP signalling pathway involved in nephric duct formation						mah	2010-09-14T03:14:59Z						biological_process											owl:Class	
GO:0055101	biolink:NamedThing	obsolete glycerophospholipase inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of a glycerophospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.	got7fsn_ti	glycerophospholipase inhibitor activity				This term was made obsolete because it refers to a non-existent molecular function term, 'glycerophosphate activity', which also cannot be found in the literature.					True				molecular_function											owl:Class	
GO:0015303	biolink:NamedThing	obsolete galactose, glucose uniporter activity	OBSOLETE. Catalysis of the reaction: galactose or glucose(out) = galactose or glucose(in).	got7fsn_ti	galactose, glucose uniporter activity				This term was made obsolete because it represents two molecular functions.	GO:0015304|GO:0050782				True				molecular_function											owl:Class	
GO:0000717	biolink:NamedThing	nucleotide-excision repair, DNA duplex unwinding	The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage.	got7fsn_ti														biological_process											owl:Class	
GO:0009296	biolink:NamedThing	obsolete flagellum assembly	OBSOLETE. The assembly of a flagellum. In bacteria, this is a whiplike motility appendage present on the surface of some species; in eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella are composed of flagellin and have the same basic structure as cilia but are longer in proportion to the cell and present in much smaller numbers.	got7fsn_ti	flagella assembly|flagellum assembly|flagellum biogenesis|flagella biogenesis					GO:0044780|GO:0060271				True				biological_process											owl:Class	
GO:2000569	biolink:NamedThing	regulation of T-helper 2 cell activation	Any process that modulates the frequency, rate or extent of T-helper 2 cell activation.	got7fsn_ti	regulation of Th2 cell activation						ebc	2011-04-03T09:14:53Z						biological_process											owl:Class	
GO:2001090	biolink:NamedThing	maltotriulose transport	The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T01:44:15Z						biological_process											owl:Class	
GO:2000743	biolink:NamedThing	negative regulation of anterior head development	Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development.	got7fsn_ti							yaf	2011-06-14T09:44:14Z						biological_process											owl:Class	
GO:0120263	biolink:NamedThing	positive regulation of heterochromatin organization	Any process that activates or increases the frequency, rate or extent of heterochromatin organization.	got7fsn_ti	up regulation of heterochromatin organization|positive regulation of heterochromatin organization|stimulation of heterochromatin organization|activation of heterochromatin organization|up-regulation of heterochromatin organization|upregulation of heterochromatin organization	https://github.com/geneontology/go-ontology/issues/20020					krc	2020-09-29T20:19:19Z						biological_process											owl:Class	
GO:0075179	biolink:NamedThing	obsolete negative regulation of calcium or calmodulin-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|negative regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0034105	biolink:NamedThing	positive regulation of tissue remodeling	Any process that activates or increases the frequency, rate, or extent of tissue remodeling.	got7fsn_ti														biological_process											owl:Class	
GO:0006075	biolink:NamedThing	(1->3)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.	got7fsn_ti	beta-1,3 glucan synthesis|beta-1,3 glucan biosynthetic process|1,3-beta-glucan synthesis|1,3-beta-glucan anabolism|1,3-beta-D-glucan biosynthetic process|1,3-beta-glucan biosynthesis|1,3-beta-glucan formation|beta-1,3 glucan anabolism|beta-1,3 glucan formation|beta-1,3 glucan biosynthesis													biological_process											owl:Class	
GO:0034033	biolink:NamedThing	purine nucleoside bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	purine nucleoside bisphosphate anabolism|purine nucleoside bisphosphate biosynthesis|purine nucleoside bisphosphate synthesis|purine nucleoside bisphosphate formation													biological_process											owl:Class	
GO:0005057	biolink:NamedThing	obsolete signal transducer activity, downstream of receptor	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell.	got7fsn_ti	intracellular signal transducer activity|receptor signaling protein activity|receptor signalling protein activity	https://github.com/geneontology/go-ontology/issues/14232			This term was obsoleted because it was not clearly defined.					True				molecular_function											owl:Class	
GO:1901110	biolink:NamedThing	actinorhodin metabolic process	The chemical reactions and pathways involving actinorhodin.	got7fsn_ti	actinorhodin metabolism						yaf	2012-07-11T03:05:37Z						biological_process											owl:Class	
GO:0006250	biolink:NamedThing	obsolete CDP reduction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	CDP reduction				This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051063				True				biological_process											owl:Class	
CHEBI:59524	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60271	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072302	biolink:NamedThing	negative regulation of metanephric glomerular mesangial cell proliferation	Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.	got7fsn_ti							mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
CHEBI:28851	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032168	biolink:NamedThing	hyphal septin ring	A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.	got7fsn_ti														cellular_component											owl:Class	
GO:0046521	biolink:NamedThing	sphingoid catabolic process	The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.	got7fsn_ti	sphingoid degradation|sphingoid catabolism|sphingoid breakdown													biological_process											owl:Class	
GO:1904632	biolink:NamedThing	cellular response to glucoside	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.	got7fsn_ti	cellular response to glucosides						sl	2015-08-28T14:01:37Z						biological_process											owl:Class	
GO:0043070	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000941	biolink:NamedThing	positive regulation of plant-type cell wall cellulose catabolic process	Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process.	got7fsn_ti	positive regulation of plant-type cell wall polysaccharide breakdown						tt	2011-08-01T02:07:21Z						biological_process											owl:Class	
GO:0002198	biolink:NamedThing	obsolete S/G2 transition of mitotic cell cycle	OBSOLETE. The transition from a cell in the S phase to the G2 phase.	got7fsn_ti	S/G2 transition of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.		hjd	2011-11-02T10:36:58Z		True				biological_process											owl:Class	
GO:0048328	biolink:NamedThing	regulation of axial mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.	got7fsn_ti														biological_process											owl:Class	
GO:1903119	biolink:NamedThing	protein localization to actin cytoskeleton	A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.	got7fsn_ti	protein localization in actin cytoskeleton|protein localisation to actin cytoskeleton|protein localisation in actin cytoskeleton						mah	2014-06-16T11:27:09Z						biological_process											owl:Class	
GO:1901889	biolink:NamedThing	negative regulation of cell junction assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.	got7fsn_ti	down-regulation of cell junction assembly|downregulation of cell junction assembly|inhibition of cell junction assembly|down regulation of cell junction assembly						tb	2013-02-06T19:40:41Z						biological_process											owl:Class	
GO:0075200	biolink:NamedThing	obsolete negative regulation of symbiont haustorium neck formation for entry into host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18779			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0007176	biolink:NamedThing	regulation of epidermal growth factor-activated receptor activity	Any process that modulates the frequency, rate or extent of EGF-activated receptor activity.	got7fsn_ti	regulation of EGF receptor activity|regulation of epidermal growth factor receptor activity|regulation of EGFR activity													biological_process											owl:Class	
GO:0035765	biolink:NamedThing	motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation	The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve.	got7fsn_ti							bf	2011-03-29T02:52:09Z						biological_process											owl:Class	
GO:0097756	biolink:NamedThing	obsolete negative regulation of blood vessel diameter	OBSOLETE. Any process that decreases the diameter of blood vessels.	got7fsn_ti	negative regulation of vasodilation				This term was obsoleted because it corresponded to an existing term, GO:0042310 ; vasocontriction.		pr	2017-02-08T15:36:16Z		True				biological_process											owl:Class	
GO:0106040	biolink:NamedThing	regulation of GABA-A receptor activity	Any process that modulates the frequency, rate or extent of GABA-A receptor activity.	got7fsn_ti							hjd	2017-07-27T18:47:02Z						biological_process											owl:Class	
GO:0045250	biolink:NamedThing	cytosolic pyruvate dehydrogenase complex	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order.	got7fsn_ti	pyruvate dehydrogenase complex (lipoamide)				Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.									cellular_component											owl:Class	
GO:0090390	biolink:NamedThing	phagosome acidification involved in apoptotic cell clearance	Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance.	got7fsn_ti							tb	2010-10-27T10:57:39Z						biological_process											owl:Class	
GO:0071677	biolink:NamedThing	positive regulation of mononuclear cell migration	Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.	got7fsn_ti	upregulation of mononuclear cell migration|activation of mononuclear cell migration|up-regulation of mononuclear cell migration|stimulation of mononuclear cell migration|up regulation of mononuclear cell migration						mah	2010-02-16T02:15:29Z						biological_process											owl:Class	
GO:0002148	biolink:NamedThing	hypochlorous acid metabolic process	The chemical reactions and pathways involving hypochlorous acid.	got7fsn_ti	HOCl metabolic process|hypochlorite metabolic process|hypochlorous acid metabolism|HClO metabolic process						hjd	2009-10-13T10:27:48Z						biological_process											owl:Class	
GO:0010462	biolink:NamedThing	regulation of light-activated voltage-gated calcium channel activity	Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity.	got7fsn_ti														biological_process											owl:Class	
GO:0033302	biolink:NamedThing	quercetin O-glucoside metabolic process	The chemical reactions and pathways involving O-glucosylated derivatives of quercetin.	got7fsn_ti	quercetin O-glucoside metabolism													biological_process											owl:Class	
GO:0009449	biolink:NamedThing	gamma-aminobutyric acid biosynthetic process	The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.	got7fsn_ti	gamma-aminobutyric acid anabolism|GABA biosynthetic process|4-aminobutanoate biosynthesis|gamma-aminobutyric acid synthesis|4-aminobutanoate biosynthetic process|4-aminobutyrate biosynthesis|gamma-aminobutyric acid biosynthesis|4-aminobutyrate biosynthetic process|gamma-aminobutyric acid formation|GABA biosynthesis				See also the biological process term 'neurotransmitter biosynthetic process ; GO:0042136'.									biological_process											owl:Class	
GO:0015364	biolink:NamedThing	dicarboxylate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out).	got7fsn_ti														molecular_function											owl:Class	
GO:1900484	biolink:NamedThing	negative regulation of protein targeting to vacuolar membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane.	got7fsn_ti	down-regulation of protein targeting to vacuolar membrane|downregulation of protein targeting to vacuolar membrane|down regulation of protein targeting to vacuolar membrane|inhibition of protein targeting to vacuolar membrane						al	2012-05-02T10:13:33Z						biological_process											owl:Class	
GO:0043939	biolink:NamedThing	negative regulation of sporulation	Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0006233	biolink:NamedThing	dTDP biosynthetic process	The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).	got7fsn_ti	dTDP synthesis|dTDP anabolism|dTDP biosynthesis|dTDP formation													biological_process											owl:Class	
GO:0045659	biolink:NamedThing	negative regulation of neutrophil differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.	got7fsn_ti	inhibition of neutrophil differentiation|down-regulation of neutrophil differentiation|down regulation of neutrophil differentiation|downregulation of neutrophil differentiation													biological_process											owl:Class	
GO:1904108	biolink:NamedThing	protein localization to ciliary inversin compartment	A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment.	got7fsn_ti	protein localisation in ciliary inversin compartment|protein localization in ciliary inversin compartment|protein localisation to ciliary inversin compartment						kmv	2015-04-01T20:54:26Z						biological_process											owl:Class	
GO:0035557	biolink:NamedThing	obsolete intracellular signal transduction involved in cell surface receptor linked signaling	OBSOLETE. The process in which a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	got7fsn_ti	intracellular signaling cascade involved in cell surface receptor linked signaling|intracellular signal transduction involved in cell surface receptor linked signaling|intracellular signal transduction involved in cell surface receptor linked signalling|intracellular signaling chain involved in cell surface receptor signaling				This term was made obsolete because the syntax of the term is incorrect.		bf	2010-05-14T01:31:05Z		True				biological_process											owl:Class	
GO:1903620	biolink:NamedThing	positive regulation of transdifferentiation	Any process that activates or increases the frequency, rate or extent of transdifferentiation.	got7fsn_ti	up regulation of transdifferentiation|activation of transdifferentiation|up-regulation of transdifferentiation|upregulation of transdifferentiation						jl	2014-11-19T11:25:14Z						biological_process											owl:Class	
GO:0036127	biolink:NamedThing	3-sulfino-L-alanine binding	Binding to 3-sulfino-L-alanine (cysteine sulfinate).	got7fsn_ti	cysteine sulfinate binding						bf	2012-02-28T03:15:40Z						molecular_function											owl:Class	
GO:0015879	biolink:NamedThing	carnitine transport	The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	got7fsn_ti	vitamin Bt transport													biological_process											owl:Class	
GO:0097251	biolink:NamedThing	leukotriene B4 biosynthetic process	The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.	got7fsn_ti	LTB4 anabolism|leukotriene B4 biosynthesis|leukotriene B4 anabolism|LTB4 biosynthesis|leukotriene B4 formation|leukotriene B4 synthesis|LTB4 synthesis|LTB4 formation						pr	2012-02-24T09:34:01Z						biological_process											owl:Class	
GO:1902402	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902737	biolink:NamedThing	dendritic filopodium	A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines.	got7fsn_ti	dendrite filopodium				Dendritic filopodia are generally less-well studied than dendritic spines because their transient nature makes them difficult to detect with traditional microscopy techniques, and because they are sometimes destroyed by sample preparation. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.		pr	2014-02-26T14:28:26Z						cellular_component											owl:Class	
GO:0046396	biolink:NamedThing	D-galacturonate metabolic process	The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls.	got7fsn_ti	D-galacturonate metabolism													biological_process											owl:Class	
GO:2000707	biolink:NamedThing	positive regulation of dense core granule biogenesis	Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis.	got7fsn_ti							yaf	2011-05-26T10:29:30Z						biological_process											owl:Class	
GO:1904694	biolink:NamedThing	negative regulation of vascular associated smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction.	got7fsn_ti	down regulation of vascular smooth muscle contraction|downregulation of vascular smooth muscle contraction|negative regulation of vascular smooth muscle contraction|inhibition of vascular smooth muscle contraction|down-regulation of vascular smooth muscle contraction						rph	2015-09-29T13:39:08Z						biological_process											owl:Class	
GO:0003398	biolink:NamedThing	glial cell differentiation involved in amphid sensory organ development	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ.	got7fsn_ti							dph	2009-12-09T09:55:27Z						biological_process											owl:Class	
GO:0043067	biolink:NamedThing	regulation of programmed cell death	Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.	got7fsn_ti	regulation of non-apoptotic programmed cell death										GO:0043070			biological_process											owl:Class	
GO:0070298	biolink:NamedThing	negative regulation of phosphorelay signal transduction system	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.	got7fsn_ti	inhibition of two-component signal transduction|down-regulation of two-component signal transduction|downregulation of two-component signal transduction|negative regulation of histidyl-aspartyl phosphorelay|negative regulation of two-component signal transduction system (phosphorelay)|down regulation of two-component signal transduction													biological_process											owl:Class	
GO:1905035	biolink:NamedThing	negative regulation of antifungal innate immune response	Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response.	got7fsn_ti	down-regulation of antifungal innate immune response|down regulation of antifungal innate immune response|downregulation of antifungal innate immune response|inhibition of antifungal innate immune response						dph	2016-03-07T20:08:05Z						biological_process											owl:Class	
GO:0032664	biolink:NamedThing	regulation of interleukin-20 production	Any process that modulates the frequency, rate, or extent of interleukin-20 production.	got7fsn_ti	regulation of interleukin-20 biosynthetic process|regulation of IL-20 production										GO:0045387			biological_process											owl:Class	
GO:0075292	biolink:NamedThing	negative regulation of aplanospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.	got7fsn_ti														biological_process											owl:Class	
GO:0150101	biolink:NamedThing	regulation of microtubule anchoring at centrosome	Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome.	got7fsn_ti							bc	2019-04-17T11:24:52Z						biological_process											owl:Class	
CHEBI:15904	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070175	biolink:NamedThing	positive regulation of enamel mineralization	Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.	got7fsn_ti														biological_process											owl:Class	
GO:1905231	biolink:NamedThing	cellular response to borneol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.	got7fsn_ti							sl	2016-06-07T17:18:44Z						biological_process											owl:Class	
GO:0036249	biolink:NamedThing	cadmium ion import into vacuole	The directed movement of cadmium ions into the vacuole.	got7fsn_ti	vacuolar cadmium import						bf	2012-05-31T11:13:44Z						biological_process											owl:Class	
GO:0009199	biolink:NamedThing	ribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	ribonucleoside triphosphate metabolism													biological_process											owl:Class	
CL:0000818	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098580	biolink:NamedThing	obsolete chromatin of active sex chromosome	OBSOLETE. Chromatin that is part of an active sex chromosome.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20159			This term was obsoleted because it represents a biological process, not a cellular localization.					True				cellular_component											owl:Class	
GO:0031538	biolink:NamedThing	negative regulation of anthocyanin metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.	got7fsn_ti	down-regulation of anthocyanin metabolic process|down regulation of anthocyanin metabolic process|negative regulation of anthocyanin metabolism|downregulation of anthocyanin metabolic process|inhibition of anthocyanin metabolic process													biological_process											owl:Class	
GO:0010649	biolink:NamedThing	regulation of cell communication by electrical coupling	Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	got7fsn_ti														biological_process											owl:Class	
GO:0000960	biolink:NamedThing	regulation of mitochondrial RNA catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.	got7fsn_ti														biological_process											owl:Class	
GO:0017052	biolink:NamedThing	obsolete insulin-like growth factor binding protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	insulin-like growth factor binding protein				This term was made obsolete because it represents a single gene product and not a complex.	GO:0016942				True				cellular_component											owl:Class	
CHEBI:18246	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903449	biolink:NamedThing	androst-4-ene-3,17-dione biosynthetic process	The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione.	got7fsn_ti	androst-4-ene-3,17-dione anabolism|androst-4-ene-3,17-dione synthesis|androstenedione biosynthetic process|androst-4-ene-3,17-dione formation|androst-4-ene-3,17-dione biosynthesis						mr	2014-09-19T20:18:19Z						biological_process											owl:Class	
GO:0030395	biolink:NamedThing	lactose binding	Binding to lactose, a disaccharide of glucose and galactose, the carbohydrate of milk.	got7fsn_ti														molecular_function											owl:Class	
GO:1900212	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.	got7fsn_ti	negative regulation of mesenchymal cell apoptosis involved in metanephros development|inhibition of mesenchymal cell apoptosis involved in metanephros development|downregulation of mesenchymal cell apoptosis involved in metanephros development|down regulation of mesenchymal cell apoptosis involved in metanephros development|down-regulation of mesenchymal cell apoptosis involved in metanephros development						yaf	2012-03-22T10:53:00Z						biological_process											owl:Class	
GO:0046187	biolink:NamedThing	acetaldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.	got7fsn_ti	acetaldehyde degradation|acetaldehyde catabolism|acetaldehyde breakdown													biological_process											owl:Class	
GO:1904675	biolink:NamedThing	regulation of somatic stem cell division	Any process that modulates the frequency, rate or extent of somatic stem cell division.	got7fsn_ti	regulation of somatic stem cell renewal						rph	2015-09-14T08:47:22Z						biological_process											owl:Class	
GO:0046367	biolink:NamedThing	allose catabolic process	The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	got7fsn_ti	allose degradation|allose breakdown|allose catabolism													biological_process											owl:Class	
GO:0003701	biolink:NamedThing	obsolete RNA polymerase I transcription factor activity	OBSOLETE. Functions to initiate or regulate RNA polymerase I transcription.	got7fsn_ti	RNA polymerase I transcription factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001181|GO:0006360				True				molecular_function											owl:Class	
GO:0006282	biolink:NamedThing	regulation of DNA repair	Any process that modulates the frequency, rate or extent of DNA repair.	got7fsn_ti														biological_process											owl:Class	
GO:0075150	biolink:NamedThing	obsolete regulation of receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation of symbiont receptor-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1990625	biolink:NamedThing	negative regulation of cytoplasmic translational initiation in response to stress	Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress.	got7fsn_ti							vw	2015-01-31T21:25:56Z						biological_process											owl:Class	
GO:1903726	biolink:NamedThing	negative regulation of phospholipid metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process.	got7fsn_ti	negative regulation of phospholipid metabolism|down-regulation of phospholipid metabolic process|downregulation of phospholipid metabolism|down regulation of phospholipid metabolic process|down regulation of phospholipid metabolism|inhibition of phospholipid metabolism|down-regulation of phospholipid metabolism|inhibition of phospholipid metabolic process|downregulation of phospholipid metabolic process						sl	2014-12-09T20:49:35Z						biological_process											owl:Class	
GO:0002737	biolink:NamedThing	negative regulation of plasmacytoid dendritic cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.	got7fsn_ti	down regulation of plasmacytoid dendritic cell cytokine production|downregulation of plasmacytoid dendritic cell cytokine production|down-regulation of plasmacytoid dendritic cell cytokine production|inhibition of plasmacytoid dendritic cell cytokine production													biological_process											owl:Class	
GO:0031359	biolink:NamedThing	integral component of chloroplast outer membrane	The component of the chloroplast outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to chloroplast outer membrane													cellular_component											owl:Class	
GO:1901952	biolink:NamedThing	negative regulation of anterograde dense core granule transport	Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport.	got7fsn_ti	down-regulation of anterograde dense core granule transport|down regulation of anterograde dense core granule transport|inhibition of anterograde dense core granule transport|downregulation of anterograde dense core granule transport						pr	2013-02-19T13:36:30Z						biological_process											owl:Class	
GO:0062143	biolink:NamedThing	L-propargylglycine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17763					dph	2019-09-02T16:45:12Z						biological_process											owl:Class	
GO:0006820	biolink:NamedThing	anion transport	The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti											GO:0006822			biological_process											owl:Class	
GO:2001249	biolink:NamedThing	negative regulation of ammonia assimilation cycle	Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle.	got7fsn_ti	negative regulation of glutamate metabolism via glutamine and ammonia|negative regulation of glutamate metabolic process via glutamine and ammonia						rl	2011-12-01T10:08:29Z						biological_process											owl:Class	
GO:0072624	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905347	biolink:NamedThing	endodeoxyribonuclease complex	A protein complex which is capable of endodeoxyribonuclease activity.	got7fsn_ti	Mus81-Eme1 complex|Mus81-Eme2 complex				An example of this is MUS81 in human (Q96NY9) in PMID:18413719 (inferred from direct assay).		bhm	2016-08-03T12:20:12Z						cellular_component											owl:Class	
GO:1900166	biolink:NamedThing	regulation of glial cell-derived neurotrophic factor production	Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production.	got7fsn_ti	regulation of glial cell line-derived neurotrophic factor secretion|regulation of glial cell-derived neurotrophic factor secretion|regulation of GDNF secretion						yaf	2012-03-08T03:44:39Z						biological_process											owl:Class	
GO:0032548	biolink:NamedThing	pyrimidine deoxyribonucleoside binding	Binding to a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.	got7fsn_ti														molecular_function											owl:Class	
GO:1905696	biolink:NamedThing	regulation of polysome binding	Any process that modulates the frequency, rate or extent of polysome binding.	got7fsn_ti	regulation of polyribosome binding						bc	2016-11-14T23:26:22Z						biological_process											owl:Class	
GO:0010601	biolink:NamedThing	positive regulation of auxin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.	got7fsn_ti														biological_process											owl:Class	
GO:0090309	biolink:NamedThing	positive regulation of DNA methylation-dependent heterochromatin assembly	Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.	got7fsn_ti	positive regulation of methylation-dependent chromatin silencing						tb	2010-04-09T02:12:53Z						biological_process											owl:Class	
GO:0002219	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901740	biolink:NamedThing	negative regulation of myoblast fusion	Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion.	got7fsn_ti	down-regulation of myoblast fusion|downregulation of myoblast fusion|inhibition of myoblast fusion|down regulation of myoblast fusion						rl	2013-01-11T20:23:55Z						biological_process											owl:Class	
PR:000001202	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990818	biolink:NamedThing	L-arginine transmembrane export from vacuole	The directed movement of L-arginine out of the vacuole, across the vacuolar membrane.	got7fsn_ti							vw	2015-08-06T15:06:33Z						biological_process											owl:Class	
GO:0046762	biolink:NamedThing	viral budding from endoplasmic reticulum membrane	A viral budding that starts with formation of a membrane curvature in the host ER membrane.	got7fsn_ti	virus budding from ER membrane by viral capsid envelopment|endoplasmic reticulum membrane viral budding during viral capsid envelopment|endoplasmic reticulum membrane viral budding|viral budding from ER membrane by viral capsid envelopment|ER membrane viral budding|virus budding from ER membrane during viral capsid envelopment|viral budding from ER membrane|ER membrane viral budding during viral capsid envelopment|virus budding from ER membrane|viral budding from ER membrane during viral capsid envelopment										GO:0046751|GO:0046764			biological_process											owl:Class	
GO:0051389	biolink:NamedThing	obsolete inactivation of MAPKK activity	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase kinase (MAPKK).	got7fsn_ti	inactivation of MAP kinase kinase activity|termination of MAP kinase kinase activity|termination of MAPKK activity	https://github.com/geneontology/go-ontology/issues/21308			This term was obsoleted because it represents a molecular function.	GO:0030291|GO:0043409				True				biological_process											owl:Class	
GO:0052470	biolink:NamedThing	obsolete modulation by host of symbiont signal transduction pathway	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0120238	biolink:NamedThing	sperm glycocalyx	The carbohydrate rich layer at the outermost periphery of a sperm cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19782					krc	2020-07-27T21:42:50Z						cellular_component											owl:Class	
GO:0071325	biolink:NamedThing	cellular response to mannitol stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.	got7fsn_ti							mah	2009-12-10T05:27:00Z						biological_process											owl:Class	
GO:0034032	biolink:NamedThing	purine nucleoside bisphosphate metabolic process	The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	purine nucleoside bisphosphate metabolism													biological_process											owl:Class	
GO:2000752	biolink:NamedThing	regulation of glucosylceramide catabolic process	Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process.	got7fsn_ti	regulation of glucosylceramide breakdown|regulation of glucosylceramide catabolism|regulation of glucosylceramide degradation						rl	2011-06-16T03:12:04Z						biological_process											owl:Class	
GO:0072746	biolink:NamedThing	cellular response to tetracycline	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.	got7fsn_ti							mah	2012-08-31T12:32:43Z						biological_process											owl:Class	
GO:0097639	biolink:NamedThing	L-lysine import across plasma membrane	The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-lysine import into cell						pr	2014-09-03T09:32:57Z			GO:1903410			biological_process											owl:Class	
GO:0045801	biolink:NamedThing	positive regulation of chitin-based cuticle tanning	Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning.	got7fsn_ti	positive regulation of cuticle hardening|upregulation of cuticle tanning|up regulation of cuticle tanning|positive regulation of cuticle tanning|stimulation of cuticle tanning|activation of cuticle tanning|up-regulation of cuticle tanning													biological_process											owl:Class	
GO:0061393	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12739			This term was obsoleted because it represents a GO-CAM model.	GO:0071470|GO:0045944	dph	2011-12-13T08:58:20Z		True				biological_process											owl:Class	
GO:0039571	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by negative regulation of STAT1 tyrosine phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT1 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT1, thereby preventing STAT1 activation.	got7fsn_ti	inhibition by virus of tyrosine phosphorylation of STAT1				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:50:38Z		True				biological_process											owl:Class	
GO:0034352	biolink:NamedThing	positive regulation of glial cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.	got7fsn_ti	stimulation of glial cell apoptosis|up-regulation of glial cell apoptosis|activation of glial cell apoptosis|positive regulation of glial cell apoptosis|upregulation of glial cell apoptosis|up regulation of glial cell apoptosis													biological_process											owl:Class	
GO:1905744	biolink:NamedThing	regulation of mRNA cis splicing, via spliceosome	Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome.	got7fsn_ti	regulation of nuclear mRNA cis splicing, via spliceosome|regulation of splicing|regulation of nuclear mRNA cis splicing, via U2-type spliceosome						vw	2016-12-07T14:01:33Z						biological_process											owl:Class	
GO:0014737	biolink:NamedThing	positive regulation of muscle atrophy	Any process that activates or increases the frequency, rate or extent of muscle atrophy.	got7fsn_ti														biological_process											owl:Class	
GO:0044571	biolink:NamedThing	[2Fe-2S] cluster assembly	The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.	got7fsn_ti	2Fe-2S cluster assembly|[2Fe-2S] cluster biosynthetic process						jl	2012-04-18T03:06:30Z						biological_process											owl:Class	
GO:0048082	biolink:NamedThing	regulation of adult chitin-containing cuticle pigmentation	Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0106140	biolink:NamedThing	P-TEFb complex binding	Binding to a P-TEFb complex.	got7fsn_ti							hjd	2018-08-17T18:17:50Z						molecular_function											owl:Class	
GO:0006205	biolink:NamedThing	obsolete pyrimidine metabolic process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	pyrimidine metabolic process				This term was made obsolete because more appropriate terms were created.	GO:0006220|GO:0006206|GO:0006213				True				biological_process											owl:Class	
GO:1901933	biolink:NamedThing	bicyclogermacrene catabolic process	The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene.	got7fsn_ti	bicyclogermacrene degradation|bicyclogermacrene breakdown|bicyclogermacrene catabolism						ms	2013-02-18T14:54:57Z						biological_process											owl:Class	
GO:0009265	biolink:NamedThing	2'-deoxyribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	2'-deoxyribonucleotide biosynthesis|2'-deoxyribonucleotide formation|2'-deoxyribonucleotide anabolism|2'-deoxyribonucleotide synthesis													biological_process											owl:Class	
OBO:GOCHE_24127	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903676	biolink:NamedThing	positive regulation of cap-dependent translational initiation	Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation.	got7fsn_ti	up-regulation of cap-dependent translational initiation|up regulation of cap-dependent translational initiation|activation of cap-dependent translational initiation|upregulation of cap-dependent translational initiation						bf	2014-11-27T19:50:39Z						biological_process											owl:Class	
GO:0071576	biolink:NamedThing	tetrahydrodictyopterin binding	Binding to tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.	got7fsn_ti	D-threo-tetrahydrobiopterin|DH4 binding						mah	2010-01-26T05:24:59Z						molecular_function											owl:Class	
GO:1905108	biolink:NamedThing	guanosine binding	Binding to guanosine.	got7fsn_ti							al	2016-04-05T08:30:47Z						molecular_function											owl:Class	
GO:0015664	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052290	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097604	biolink:NamedThing	temperature-gated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).	got7fsn_ti	heat-activated cation channel activity|temperature-dependent cation channel activity|temperature gated cation channel activity|temperature-activated cation channel activity						pr	2014-05-12T13:13:46Z						molecular_function											owl:Class	
GO:0019764	biolink:NamedThing	obsolete high affinity Fc receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	high affinity Fc receptor activity				This term was made obsolete because it is an unnecessary grouping term.	GO:0019771|GO:0019768				True				molecular_function											owl:Class	
GO:0032874	biolink:NamedThing	positive regulation of stress-activated MAPK cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.	got7fsn_ti	up regulation of stress-activated MAPK cascade|positive regulation of stress-activated MAPK signalling pathway|up-regulation of stress-activated MAPK cascade|upregulation of stress-activated MAPK cascade|positive regulation of p38 MAPK signaling|stimulation of stress-activated MAPK cascade|positive regulation of stress-activated MAPK signaling pathway|positive regulation of p38 MAPK signalling|positive regulation of stress-activated MAPKKK signaling pathway|positive regulation of stress-activated MAPKKK cascade|positive regulation of stress-activated MAPKKK signalling pathway|activation of stress-activated MAPK cascade													biological_process											owl:Class	
GO:2000079	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.	got7fsn_ti	regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation						tb	2010-08-27T11:22:56Z						biological_process											owl:Class	
GO:0052569	biolink:NamedThing	obsolete response to defense-related symbiont nitric oxide production	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of nitric oxide produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	response to defense-related symbiont nitric oxide production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1905212	biolink:NamedThing	positive regulation of fibroblast chemotaxis	Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis.	got7fsn_ti	up regulation of fibroblast chemotaxis|upregulation of fibroblast chemotaxis|up-regulation of fibroblast chemotaxis|activation of fibroblast chemotaxis						sl	2016-06-02T20:08:59Z						biological_process											owl:Class	
GO:1905414	biolink:NamedThing	negative regulation of dense core granule exocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis.	got7fsn_ti	negative regulation of dense core vesicle exocytosis|inhibition of dense core granule exocytosis|inhibition of dense core vesicle exocytosis|down-regulation of dense core granule exocytosis|downregulation of dense core granule exocytosis|down regulation of dense core granule exocytosis|down-regulation of dense core vesicle exocytosis|down regulation of dense core vesicle exocytosis|downregulation of dense core vesicle exocytosis						bf	2016-08-31T08:02:28Z						biological_process											owl:Class	
GO:0005651	biolink:NamedThing	obsolete exportin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	exportin				This term was made obsolete because it represents a single gene product and not a complex.	GO:0017056|GO:0005634|GO:0005643|GO:0005737				True				cellular_component											owl:Class	
GO:0071337	biolink:NamedThing	negative regulation of hair follicle cell proliferation	Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation.	got7fsn_ti	inhibition of hair follicle cell proliferation|down regulation of hair follicle cell proliferation|downregulation of hair follicle cell proliferation|down-regulation of hair follicle cell proliferation						mah	2009-12-11T10:59:20Z						biological_process											owl:Class	
GO:0016271	biolink:NamedThing	obsolete tissue death	OBSOLETE. A permanent cessation of all vital functions of a tissue.	got7fsn_ti					This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0012501|GO:0008219				True				biological_process											owl:Class	
GO:0008572	biolink:NamedThing	obsolete nucleoplasmin ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP required for the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes.	got7fsn_ti	nucleoplasmin ATPase activity			GO:0016887	This term was made obsolete because it represents a class of gene products, and its definition incorporates process information.	GO:0006333				True				molecular_function											owl:Class	
GO:0006059	biolink:NamedThing	hexitol metabolic process	The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule.	got7fsn_ti	sugar alcohol (hexitol) metabolic process|sugar alcohol (hexitol) metabolism|hexitol metabolism													biological_process											owl:Class	
GO:0061903	biolink:NamedThing	positive regulation of 1-phosphatidylinositol-3-kinase activity	Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.	got7fsn_ti							dph	2017-06-22T19:54:53Z						biological_process											owl:Class	
GO:0070425	biolink:NamedThing	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.	got7fsn_ti	negative regulation of NOD signaling pathway|negative regulation of nucleotide-binding oligomerization domain containing signalling pathway													biological_process											owl:Class	
GO:0010116	biolink:NamedThing	positive regulation of abscisic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.	got7fsn_ti	upregulation of abscisic acid biosynthetic process|stimulation of abscisic acid biosynthetic process|positive regulation of abscisic acid biosynthesis|positive regulation of abscisic acid formation|positive regulation of abscisic acid anabolism|activation of abscisic acid biosynthetic process|up regulation of abscisic acid biosynthetic process|up-regulation of abscisic acid biosynthetic process|positive regulation of abscisic acid synthesis													biological_process											owl:Class	
GO:1904170	biolink:NamedThing	regulation of bleb assembly	Any process that modulates the frequency, rate or extent of bleb assembly.	got7fsn_ti	regulation of cell blebbing						als	2015-04-23T09:32:19Z						biological_process											owl:Class	
GO:1904463	biolink:NamedThing	ergosteryl 3-beta-D-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside.	got7fsn_ti	ergosteryl 3-beta-D-glucoside anabolism|ergosteryl 3-beta-D-glucoside synthesis|ergosteryl 3-beta-D-glucoside biosynthesis|ergosteryl 3-beta-D-glucoside formation						mcc	2015-07-09T19:36:31Z						biological_process											owl:Class	
GO:2000492	biolink:NamedThing	regulation of interleukin-18-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway.	got7fsn_ti	regulation of interleukin-18-mediated signalling pathway						pr	2011-03-16T01:59:18Z						biological_process											owl:Class	
GO:0080050	biolink:NamedThing	regulation of seed development	Any process that modulates the frequency, rate or extent of seed development.	got7fsn_ti														biological_process											owl:Class	
CHEBI:30408	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044334	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of epithelial cell to mesenchymal cell transition.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in positive regulation of epithelial to mesenchymal transition|canonical Wnt-activated signaling pathway involved in positive regulation of epithelial to mesenchymal transition|canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition						jl	2010-08-20T02:35:17Z						biological_process											owl:Class	
GO:0098503	biolink:NamedThing	obsolete DNA 3' dephosphorylation	OBSOLETE. The process of removing a 3' phosphate group from a DNA molecule.	got7fsn_ti					This term was obsoleted because it represents a molecular function, and not a specific coordinated process.		dos	2013-09-18T14:51:17Z		True				biological_process											owl:Class	
GO:0034144	biolink:NamedThing	negative regulation of toll-like receptor 4 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 4 signalling pathway|negative regulation of TLR4 signaling pathway													biological_process											owl:Class	
GO:0062227	biolink:NamedThing	positive regulation of adult somatic muscle development	Any process that increases the rate, frequency or extent of adult somatic muscle development.	got7fsn_ti							dph	2020-03-16T13:29:41Z						biological_process											owl:Class	
GO:0009315	biolink:NamedThing	obsolete drug resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	drug resistance			GO:0009410	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0120070	biolink:NamedThing	negative regulation of stomach fundus smooth muscle contraction	Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction.	got7fsn_ti							krc	2017-06-13T23:27:40Z						biological_process											owl:Class	
GO:1905749	biolink:NamedThing	regulation of endosome to plasma membrane protein transport	Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport.	got7fsn_ti							pga	2016-12-09T13:46:13Z						biological_process											owl:Class	
GO:0042420	biolink:NamedThing	dopamine catabolic process	The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	got7fsn_ti	dopamine degradation|dopamine catabolism|dopamine breakdown													biological_process											owl:Class	
GO:0008538	biolink:NamedThing	obsolete proteasome activator activity	OBSOLETE. Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.	got7fsn_ti	PA28|proteasome activator activity				The term was made obsolete because 'proteasome' is not a valid molecular function term.	GO:0061136|GO:0061133				True				molecular_function											owl:Class	
GO:0008603	biolink:NamedThing	cAMP-dependent protein kinase regulator activity	Modulation of the activity of the enzyme cAMP-dependent protein kinase.	got7fsn_ti	cyclic AMP-dependent protein kinase regulator activity|3',5' cAMP-dependent protein kinase regulator activity|3',5'-cAMP-dependent protein kinase regulator activity|adenosine 3',5'-cyclophosphate-dependent protein kinase regulator activity|cAMP-dependent protein kinase, intrinsic regulator activity													molecular_function											owl:Class	
GO:1904276	biolink:NamedThing	regulation of wax biosynthetic process	Any process that modulates the frequency, rate or extent of wax biosynthetic process.	got7fsn_ti	regulation of wax anabolism|regulation of wax formation|regulation of wax synthesis|regulation of wax biosynthesis						tb	2015-06-03T17:20:06Z						biological_process											owl:Class	
GO:1901093	biolink:NamedThing	regulation of protein homotetramerization	Any process that modulates the frequency, rate or extent of protein homotetramerization.	got7fsn_ti	regulation of protein homotetramer biosynthesis|regulation of protein homotetramer biosynthetic process|regulation of protein homotetramer formation|regulation of protein homotetramer assembly						pm	2012-07-06T12:57:33Z						biological_process											owl:Class	
GO:1904520	biolink:NamedThing	regulation of myofibroblast cell apoptotic process	Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process.	got7fsn_ti	regulation of MFB apoptotic process|regulation of MFB apoptosis|regulation of myofibroblast cell apoptosis						sl	2015-07-29T15:52:14Z						biological_process											owl:Class	
GO:0042024	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904811	biolink:NamedThing	positive regulation of dense core granule transport	Any process that activates or increases the frequency, rate or extent of dense core granule transport.	got7fsn_ti	upregulation of dense core vesicle transport|up regulation of dense core granule transport|up regulation of dense core vesicle transport|up-regulation of dense core granule transport|up-regulation of dense core vesicle transport|upregulation of dense core granule transport|activation of dense core granule transport|positive regulation of dense core vesicle transport|activation of dense core vesicle transport				cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).		es	2015-11-11T10:40:25Z						biological_process											owl:Class	
GO:1905521	biolink:NamedThing	regulation of macrophage migration	Any process that modulates the frequency, rate or extent of macrophage migration.	got7fsn_ti							sl	2016-10-03T15:29:06Z						biological_process											owl:Class	
GO:0046560	biolink:NamedThing	obsolete scytalidopepsin B activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, cleaving Phe24-Phe, but not Leu15-Tyr and Phe25-Tyr in the B chain of insulin.	got7fsn_ti	Scytalidium aspartic proteinase B activity|scytalidopepsin B activity|Ganoderma lucidum carboxyl proteinase activity|Scytalidium lignicolum aspartic proteinase B|Ganoderma lucidum aspartic proteinase activity|SLB			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:57739	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044477	biolink:NamedThing	envenomation resulting in negative regulation of platelet aggregation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism.	got7fsn_ti							jl	2012-01-19T02:36:44Z						biological_process											owl:Class	
GO:0014739	biolink:NamedThing	positive regulation of muscle hyperplasia	Any process that activates or increases the frequency, rate or extent of muscle hyperplasia.	got7fsn_ti														biological_process											owl:Class	
GO:2001053	biolink:NamedThing	regulation of mesenchymal cell apoptotic process	Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process.	got7fsn_ti	regulation of mesenchymal cell apoptosis						yaf	2011-09-08T02:49:59Z						biological_process											owl:Class	
GO:0070454	biolink:NamedThing	negative regulation of heme biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.	got7fsn_ti	down regulation of heme biosynthetic process|downregulation of heme biosynthetic process|negative regulation of heme formation|negative regulation of haem biosynthetic process|negative regulation of heme anabolism|down-regulation of heme biosynthetic process|negative regulation of heme synthesis|negative regulation of heme biosynthesis|inhibition of heme biosynthetic process													biological_process											owl:Class	
GO:0060190	biolink:NamedThing	negative regulation of protein desumoylation	Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.	got7fsn_ti														biological_process											owl:Class	
GO:0051677	biolink:NamedThing	pullulan biosynthetic process	The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.	got7fsn_ti														biological_process											owl:Class	
GO:0000734	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031393	biolink:NamedThing	negative regulation of prostaglandin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	got7fsn_ti	negative regulation of prostaglandin formation|downregulation of prostaglandin biosynthetic process|negative regulation of prostaglandin anabolism|down-regulation of prostaglandin biosynthetic process|negative regulation of prostaglandin biosynthesis|inhibition of prostaglandin biosynthetic process|negative regulation of prostaglandin synthesis|down regulation of prostaglandin biosynthetic process													biological_process											owl:Class	
GO:0010023	biolink:NamedThing	proanthocyanidin biosynthetic process	The chemical reactions and pathways resulting in the formation of proanthocyanidin.	got7fsn_ti	proanthocyanidin anabolism|proanthocyanidin formation|proanthocyanidin biosynthesis|proanthocyanidin synthesis											MetaCyc:PWY-641		biological_process											owl:Class	
GO:1902606	biolink:NamedThing	regulation of large conductance calcium-activated potassium channel activity	Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity.	got7fsn_ti	regulation of BK KCa channels|regulation of BK channel activity|regulation of large conductance KCa channels|regulation of BK calcium-activated potassium channel activity						sl	2014-01-02T18:51:03Z						biological_process											owl:Class	
GO:0099178	biolink:NamedThing	regulation of retrograde trans-synaptic signaling by endocanabinoid	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid.	got7fsn_ti	regulation of endocannabinoid-mediated retrograde trans-synaptic signaling													biological_process											owl:Class	
GO:0042339	biolink:NamedThing	keratan sulfate metabolic process	The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.	got7fsn_ti	keratan sulphate metabolism|keratan sulphate metabolic process|keratan sulfate metabolism													biological_process											owl:Class	
GO:0045750	biolink:NamedThing	obsolete positive regulation of S phase of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of S phase of mitotic cell cycle activity.	got7fsn_ti	up regulation of S phase of mitotic cell cycle|positive regulation of S-phase of mitotic cell cycle|up-regulation of S phase of mitotic cell cycle|upregulation of S phase of mitotic cell cycle|activation of S phase of mitotic cell cycle|positive regulation of S phase of mitotic cell cycle|stimulation of S phase of mitotic cell cycle				This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.					True				biological_process											owl:Class	
GO:0035828	biolink:NamedThing	obsolete renal rubidium ion transport	OBSOLETE. The directed movement of rubidium ions (Rb+) by the kidney.	got7fsn_ti	renal Rb+ transport|renal rubidium cation transport				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-04T02:58:50Z		True				biological_process											owl:Class	
GO:2001033	biolink:NamedThing	negative regulation of double-strand break repair via nonhomologous end joining	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	got7fsn_ti	negative regulation of NHEJ						yaf	2011-08-24T09:25:46Z						biological_process											owl:Class	
GO:0075077	biolink:NamedThing	obsolete negative regulation by host of symbiont adenylate cyclase activity	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		This term was obsoleted because it represents a molecular function.			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0042557	biolink:NamedThing	eukaryotic elongation factor-2 kinase activator activity	Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase.	got7fsn_ti	eEF-2 kinase activator													molecular_function											owl:Class	
GO:0043496	biolink:NamedThing	regulation of protein homodimerization activity	Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.	got7fsn_ti					Note that protein homodimerization is a molecular function: 'protein homodimerization activity ; GO:0042803'.									biological_process											owl:Class	
GO:0051352	biolink:NamedThing	negative regulation of ligase activity	Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.	got7fsn_ti	down-regulation of ligase activity|ligase inhibitor|inhibition of ligase activity|down regulation of ligase activity|downregulation of ligase activity													biological_process											owl:Class	
GO:0045565	biolink:NamedThing	obsolete negative regulation of TRAIL receptor 1 biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.	got7fsn_ti	negative regulation of TRAIL receptor 1 formation|down regulation of TRAIL receptor 1 biosynthetic process|downregulation of TRAIL receptor 1 biosynthetic process|down-regulation of TRAIL receptor 1 biosynthetic process|negative regulation of TRAIL receptor 1 synthesis|negative regulation of TRAIL receptor 1 anabolism|inhibition of TRAIL receptor 1 biosynthetic process|negative regulation of TRAIL receptor 1 biosynthesis	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0070948	biolink:NamedThing	regulation of neutrophil mediated cytotoxicity	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.	got7fsn_ti	regulation of neutrophil mediated cell killing						mah	2009-10-01T02:14:36Z						biological_process											owl:Class	
GO:0015710	biolink:NamedThing	tellurite transport	The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
PO:0000290	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075167	biolink:NamedThing	obsolete negative regulation of G-protein gamma subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0035480	biolink:NamedThing	regulation of Notch signaling pathway involved in heart induction	Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.	got7fsn_ti	regulation of Notch signalling pathway involved in heart induction						bf	2010-04-23T10:40:48Z						biological_process											owl:Class	
GO:0046489	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:16454	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900490	biolink:NamedThing	positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	Any process that activates or increases the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.	got7fsn_ti	up-regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|up regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|positive regulation of HMG-CoA reductase activity|up-regulation of HMG-CoA reductase activity|upregulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|activation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|activation of HMG-CoA reductase activity|positive regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|upregulation of HMG-CoA reductase activity|upregulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up regulation of HMG-CoA reductase activity|activation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up-regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity						al	2012-05-02T03:01:43Z						biological_process											owl:Class	
GO:0030949	biolink:NamedThing	positive regulation of vascular endothelial growth factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.	got7fsn_ti	positive regulation of VEGF receptor signaling pathway|up-regulation of vascular endothelial growth factor receptor signaling pathway|stimulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of VEGF receptor signalling pathway|upregulation of vascular endothelial growth factor receptor signaling pathway|activation of vascular endothelial growth factor receptor signaling pathway|positive regulation of vascular endothelial growth factor receptor signalling pathway|up regulation of vascular endothelial growth factor receptor signaling pathway													biological_process											owl:Class	
GO:1990561	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion starvation	OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of copper ions.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0035874	al	2014-11-25T14:21:55Z		True				biological_process											owl:Class	
GO:0046373	biolink:NamedThing	L-arabinose metabolic process	The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc.	got7fsn_ti	L-arabinose metabolism													biological_process											owl:Class	
GO:0006246	biolink:NamedThing	dTDP catabolic process	The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate.	got7fsn_ti	dTDP catabolism|dTDP breakdown|dTDP degradation													biological_process											owl:Class	
GO:0008591	biolink:NamedThing	regulation of Wnt signaling pathway, calcium modulating pathway	Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).	got7fsn_ti	regulation of Wnt-activated signaling pathway, calcium modulating pathway|regulation of frizzled-2 signaling pathway|regulation of frizzled-2 signalling pathway|regulation of Wnt receptor signaling pathway, calcium modulating pathway													biological_process											owl:Class	
GO:1902593	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0110136	biolink:NamedThing	protein-RNA complex remodeling	The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex.	got7fsn_ti							kmv	2019-01-22T19:23:17Z						biological_process											owl:Class	
GO:1903286	biolink:NamedThing	regulation of potassium ion import	Any process that modulates the frequency, rate or extent of potassium ion import.	got7fsn_ti	regulation of potassium ion uptake|regulation of potassium import						rl	2014-08-11T14:26:16Z						biological_process											owl:Class	
GO:0010578	biolink:NamedThing	regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway.	got7fsn_ti	regulation of adenylate cyclase activity involved in G-protein signalling|regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|regulation of adenylate cyclase activity involved in G-protein signaling pathway													biological_process											owl:Class	
GO:1903263	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033508	biolink:NamedThing	glutamate catabolic process to butyrate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.	got7fsn_ti	glutamate breakdown to butyrate|glutamate degradation to butyrate											MetaCyc:PWY-5087		biological_process											owl:Class	
GO:0032744	biolink:NamedThing	positive regulation of interleukin-20 production	Any process that activates or increases the frequency, rate, or extent of interleukin-20 production.	got7fsn_ti	activation of interleukin-20 production|positive regulation of interleukin-20 biosynthetic process|positive regulation of IL-20 production|up regulation of interleukin-20 production|up-regulation of interleukin-20 production|stimulation of interleukin-20 production|upregulation of interleukin-20 production										GO:0045389			biological_process											owl:Class	
GO:0099515	biolink:NamedThing	actin filament-based transport	The transport of organelles or other particles from one location in the cell to another along actin filaments.	got7fsn_ti							tb	2009-05-27T10:56:08Z						biological_process											owl:Class	
GO:0046326	biolink:NamedThing	positive regulation of glucose import	Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.	got7fsn_ti	activation of glucose import|positive regulation of glucose uptake|up-regulation of glucose import|up regulation of glucose import|upregulation of glucose import|stimulation of glucose import													biological_process											owl:Class	
GO:0046261	biolink:NamedThing	obsolete 4-nitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrotoluene, 1-methyl-4-nitrobenzene.	got7fsn_ti	4-nitrotoluene biosynthesis|4-nitrotoluene formation|4NT biosynthetic process|4-nitrotoluene biosynthetic process|4-nitrotoluene synthesis|4-nitrotoluene anabolism|4NT biosynthesis			GO:0019257	This term was made obsolete because 4-nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
CHEBI:35366	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098879	biolink:NamedThing	structural constituent of postsynaptic specialization	The action of a molecule that contributes to the structural integrity of a postsynaptic specialization.	got7fsn_ti														molecular_function											owl:Class	
GO:0006256	biolink:NamedThing	UDP catabolic process	The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate.	got7fsn_ti	UDP catabolism|UDP degradation|UDP breakdown													biological_process											owl:Class	
GO:1904152	biolink:NamedThing	regulation of retrograde protein transport, ER to cytosol	Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.	got7fsn_ti	regulation of protein dislocation from ER|regulation of protein retrotranslocation from ER|regulation of retrograde protein transport, endoplasmic reticulum to cytosol						bf	2015-04-15T09:23:06Z						biological_process											owl:Class	
GO:1903725	biolink:NamedThing	regulation of phospholipid metabolic process	Any process that modulates the frequency, rate or extent of phospholipid metabolic process.	got7fsn_ti	regulation of phospholipid metabolism						sl	2014-12-09T20:49:27Z						biological_process											owl:Class	
GO:0062100	biolink:NamedThing	positive regulation of programmed necrotic cell death	Any process that increases the frequency, rate or extent of programmed necrotic cell death.	got7fsn_ti							dph	2018-11-29T15:08:35Z						biological_process											owl:Class	
GO:1904052	biolink:NamedThing	negative regulation of protein targeting to vacuole involved in autophagy	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy.	got7fsn_ti	downregulation of protein targeting to vacuole involved in autophagy|down-regulation of protein targeting to vacuole involved in autophagy|inhibition of protein targeting to vacuole involved in autophagy|down regulation of protein targeting to vacuole involved in autophagy				An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).		pad	2015-03-17T13:54:22Z						biological_process											owl:Class	
GO:1903032	biolink:NamedThing	negative regulation of microtubule plus-end binding	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding.	got7fsn_ti	down regulation of microtubule plus-end binding|downregulation of microtubule plus-end binding|down-regulation of microtubule plus-end binding|inhibition of microtubule plus-end binding						hjd	2014-05-16T18:38:32Z						biological_process											owl:Class	
GO:1901182	biolink:NamedThing	regulation of camalexin biosynthetic process	Any process that modulates the frequency, rate or extent of camalexin biosynthetic process.	got7fsn_ti	regulation of camalexin formation|regulation of camalexin biosynthesis|regulation of camalexin synthesis|regulation of camalexin anabolism						tb	2012-07-23T02:16:52Z						biological_process											owl:Class	
GO:0033141	biolink:NamedThing	positive regulation of peptidyl-serine phosphorylation of STAT protein	Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	got7fsn_ti	upregulation of serine phosphorylation of STAT3 protein|up regulation of serine phosphorylation of STAT3 protein|up-regulation of serine phosphorylation of STAT3 protein|activation of serine phosphorylation of STAT3 protein|positive regulation of serine phosphorylation of STAT3 protein										GO:1903263			biological_process											owl:Class	
GO:0006193	biolink:NamedThing	ITP catabolic process	The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate.	got7fsn_ti	ITP degradation|ITP catabolism|ITP breakdown|ITP hydrolysis													biological_process											owl:Class	
GO:0051939	biolink:NamedThing	gamma-aminobutyric acid import	The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle.	got7fsn_ti	gamma-aminobutyrate import|GABA import|gamma-aminobutyric acid uptake|4-aminobutyrate import													biological_process											owl:Class	
GO:1902926	biolink:NamedThing	inulin metabolic process	The chemical reactions and pathways involving inulin.	got7fsn_ti	inulin metabolism				SUC2 in S. cerevisiae strain JZ1C in PMID:23104410.		se	2014-04-21T23:54:33Z						biological_process											owl:Class	
GO:0039566	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by tyrosine dephosphorylation of STAT1	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by the removal of phosphoric residues from STAT1-O-phospho-tyrosine to form STAT1-tyrosine. For example, the viral phosphatase VH1 dephosphorylates STAT1 to reverse STAT1 activation.	got7fsn_ti	viral tyrosine phosphatase activity involved in suppression of host STAT1|suppression by virus of host STAT1 activity by peptidyl-tyrosine dephosphorylation of STAT1				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:08:32Z		True				biological_process											owl:Class	
GO:0050523	biolink:NamedThing	obsolete oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD or NADP.	got7fsn_ti	oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0030613				True				molecular_function											owl:Class	
GO:0060940	biolink:NamedThing	epithelial to mesenchymal transition involved in cardiac fibroblast development	A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.	got7fsn_ti							dph	2009-09-29T01:32:36Z						biological_process											owl:Class	
GO:0010980	biolink:NamedThing	positive regulation of vitamin D 24-hydroxylase activity	Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.	got7fsn_ti							tb	2009-06-01T11:47:19Z						biological_process											owl:Class	
GO:0070350	biolink:NamedThing	regulation of white fat cell proliferation	Any process that modulates the frequency, rate or extent of white fat cell proliferation.	got7fsn_ti	regulation of white adipose cell proliferation|regulation of white adipocyte proliferation													biological_process											owl:Class	
GO:0003806	biolink:NamedThing	obsolete coagulation factor XIIa activity	OBSOLETE. Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.	got7fsn_ti	blood-coagulation factor XIIf|hageman factor activity|kallikreinogen activator|activated beta blood-coagulation factor XII|hageman factor beta-fragment|blood-coagulation factor XIIabeta|hageman factor fragment HFf|blood coagulation factor XII activity|hageman factor (activated)|prekallikrein activator|prealbumin activator|coagulation factor XIIa activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1904594	biolink:NamedThing	regulation of termination of RNA polymerase II transcription	Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription.	got7fsn_ti	regulation of RNA 3'-end formation by RNA polymerase II|regulation of RNA polymerase II transcription termination|regulation of transcription termination from Pol II promoter|regulation of transcription termination from RNA polymerase II promoter|regulation of RNA polymerase II transcription termination factor activity						al	2015-08-25T08:56:06Z						biological_process											owl:Class	
GO:0090209	biolink:NamedThing	negative regulation of triglyceride metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.	got7fsn_ti							tb	2009-12-23T10:35:06Z						biological_process											owl:Class	
GO:0034120	biolink:NamedThing	positive regulation of erythrocyte aggregation	Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation.	got7fsn_ti	positive regulation of red blood cell aggregation|positive regulation of RBC aggregation													biological_process											owl:Class	
GO:0050482	biolink:NamedThing	arachidonic acid secretion	The controlled release of arachidonic acid from a cell or a tissue.	got7fsn_ti					This term should be used to annotate release of arachidonic acid from the cell. For the hydrolytic release of arachidonic acid from a phospholipid, consider instead annotating to 'phospholipase A2 activity ; GO:0004623'.									biological_process											owl:Class	
GO:0033005	biolink:NamedThing	positive regulation of mast cell activation	Any process that activates or increases the frequency, rate, or extent of mast cell activation.	got7fsn_ti														biological_process											owl:Class	
GO:1901524	biolink:NamedThing	regulation of mitophagy	Any process that modulates the frequency, rate or extent of macromitophagy.	got7fsn_ti	regulation of macromitophagy						krc	2012-10-22T16:56:45Z						biological_process											owl:Class	
GO:1905637	biolink:NamedThing	regulation of mitochondrial mRNA catabolic process	Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.	got7fsn_ti							tb	2016-11-03T20:23:57Z						biological_process											owl:Class	
GO:1902780	biolink:NamedThing	response to nonane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.	got7fsn_ti							tt	2014-03-21T03:24:50Z						biological_process											owl:Class	
GO:0001950	biolink:NamedThing	obsolete plasma membrane enriched fraction	OBSOLETE. The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes.	got7fsn_ti	plasma membrane enriched fraction|PME fraction				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005886				True				cellular_component											owl:Class	
GO:2000278	biolink:NamedThing	regulation of DNA biosynthetic process	Any process that modulates the frequency, rate or extent of DNA biosynthetic process.	got7fsn_ti	regulation of DNA biosynthesis|regulation of DNA synthesis|regulation of DNA anabolism|regulation of DNA formation						yaf	2010-12-08T04:48:15Z						biological_process											owl:Class	
GO:0120184	biolink:NamedThing	negative regulation of focal adhesion disassembly	Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components.	got7fsn_ti							krc	2018-07-12T18:30:06Z						biological_process											owl:Class	
UBERON:0001707	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001159	biolink:NamedThing	regulation of protein localization by the Cvt pathway	Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway.	got7fsn_ti	regulation of cytoplasm to vacuole targeting|regulation of cytoplasm-to-vacuole targeting						jp	2011-10-25T10:22:24Z						biological_process											owl:Class	
GO:0002924	biolink:NamedThing	negative regulation of humoral immune response mediated by circulating immunoglobulin	Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.	got7fsn_ti	down-regulation of humoral immune response mediated by circulating immunoglobulin|inhibition of humoral immune response mediated by circulating immunoglobulin|down regulation of humoral immune response mediated by circulating immunoglobulin|downregulation of humoral immune response mediated by circulating immunoglobulin													biological_process											owl:Class	
GO:2000426	biolink:NamedThing	negative regulation of apoptotic cell clearance	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance.	got7fsn_ti	negative regulation of programmed cell clearance|negative regulation of apoptotic cell removal|negative regulation of efferocytosis						bf	2011-02-25T11:50:39Z						biological_process											owl:Class	
CL:0000037	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000568	biolink:NamedThing	positive regulation of memory T cell activation	Any process that activates or increases the frequency, rate or extent of memory T cell activation.	got7fsn_ti							ebc	2011-04-03T09:10:12Z						biological_process											owl:Class	
PO:0009032	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002848	biolink:NamedThing	positive regulation of T cell tolerance induction to tumor cell	Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell.	got7fsn_ti	upregulation of T cell tolerance induction to tumor cell|stimulation of T cell tolerance induction to tumor cell|up-regulation of T cell tolerance induction to tumor cell|activation of T cell tolerance induction to tumor cell|up regulation of T cell tolerance induction to tumor cell													biological_process											owl:Class	
GO:0015875	biolink:NamedThing	obsolete vitamin or cofactor transport	OBSOLETE. The directed movement of vitamins or cofactors into, out of or within a cell, or between cells.	got7fsn_ti	vitamin or cofactor transport				This term was made obsolete because it was replaced by more specific terms.	GO:0051180				True				biological_process											owl:Class	
GO:0071262	biolink:NamedThing	regulation of translational initiation in response to starvation	Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.	got7fsn_ti	regulation of translational initiation in response to nutrient starvation						mah	2009-12-08T05:31:05Z						biological_process											owl:Class	
GO:0090349	biolink:NamedThing	negative regulation of cellular organohalogen metabolic process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.	got7fsn_ti							tb	2010-06-02T10:36:42Z						biological_process											owl:Class	
GO:0008958	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0120291	biolink:NamedThing	negative regulation of mitotic recombination involved in replication fork processing	Any process that inhibits or decreases the rate of mitotic DNA recombination during replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.	got7fsn_ti	suppression of template switching during replication fork processing|maintenance of template fidelity during replication fork processing|negative regulation of template switch recombination involved in replication fork processing						krc	2021-01-06T01:21:55Z						biological_process											owl:Class	
GO:1905711	biolink:NamedThing	response to phosphatidylethanolamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.	got7fsn_ti	response to PtdEtn|response to PE|response to phosphatidyl(amino)ethanols|response to phosphatidylethanolamines						sl	2016-11-21T19:55:32Z						biological_process											owl:Class	
GO:0033667	biolink:NamedThing	obsolete negative regulation of growth or development of symbiont in host	OBSOLETE. Any process by which the symbiont stops, prevents or reduces its increase in size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti	negative regulation of growth or development of symbiont within host|negative regulation of growth or development of symbiont in host|down regulation of growth or development of organism within host|downregulation of growth or development of organism within host|down-regulation of growth or development of organism within host|inhibition of growth of development of organism within host|negative regulation of invasive growth				This term was made obsolete because it contained a conjunction (or).	GO:0044131				True				biological_process											owl:Class	
GO:1904289	biolink:NamedThing	regulation of mitotic DNA damage checkpoint	Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint.	got7fsn_ti							kmv	2015-06-09T13:03:11Z						biological_process											owl:Class	
GO:1905365	biolink:NamedThing	regulation of intralumenal vesicle formation	Any process that modulates the frequency, rate or extent of intralumenal vesicle formation.	got7fsn_ti	regulation of endosome membrane budding						bc	2016-08-16T12:00:01Z						biological_process											owl:Class	
GO:0043411	biolink:NamedThing	obsolete myopalladin binding	OBSOLETE. Binding to myopalladin, a myofibrillar protein with titin-like Ig domains.	got7fsn_ti	myopalladin binding			GO:0008092	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:0015306	biolink:NamedThing	sialate:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in).	got7fsn_ti	sialate transporter activity|sialate/cation symporter activity|cation/sialate symporter activity|cation:sialate symporter activity													molecular_function											owl:Class	
CHEBI:29919	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903559	biolink:NamedThing	3-cyano-L-alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine.	got7fsn_ti	3-cyano-L-alanine catabolism|3-cyano-L-alanine breakdown|3-cyano-L-alanine degradation						kmv	2014-10-21T17:13:10Z						biological_process											owl:Class	
GO:0061464	biolink:NamedThing	obsolete plasma membrane part of cell-substrate junction	OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell-substrate junction.	got7fsn_ti					The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM.		dph	2012-10-19T11:04:48Z		True				cellular_component											owl:Class	
GO:0001129	biolink:NamedThing	obsolete RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly	OBSOLETE. Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), to facilitate the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.	got7fsn_ti	TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly|TATA-binding protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.		krc	2011-01-20T02:53:35Z		True				molecular_function											owl:Class	
GO:0034180	biolink:NamedThing	negative regulation of toll-like receptor 13 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 13 signalling pathway|negative regulation of TLR13 signaling pathway													biological_process											owl:Class	
GO:0045752	biolink:NamedThing	positive regulation of Toll signaling pathway	Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.	got7fsn_ti	positive regulation of Tl signalling pathway|upregulation of Toll signaling pathway|up regulation of Toll signaling pathway|stimulation of Toll signaling pathway|positive regulation of Tl signaling pathway|activation of Toll signaling pathway|up-regulation of Toll signaling pathway													biological_process											owl:Class	
GO:0005755	biolink:NamedThing	obsolete hydrogen-transporting ATP synthase, coupling factor CF(0)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	hydrogen-transporting ATP synthase, coupling factor CF(0)				This term was made obsolete because more specific terms were created.	GO:0045263				True				cellular_component											owl:Class	
GO:0006494	biolink:NamedThing	obsolete protein amino acid terminal glycosylation	OBSOLETE. A protein amino acid glycosylation process in which a sugar unit is added to a free alpha-amino or alpha-carboxyl terminal of a peptide.	got7fsn_ti	protein amino acid terminal glycosylation				This term was made obsolete because the term name is ambiguous.	GO:0006486				True				biological_process											owl:Class	
GO:0042899	biolink:NamedThing	arabinan transmembrane transport	The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	arabinan transport													biological_process											owl:Class	
GO:2000845	biolink:NamedThing	positive regulation of testosterone secretion	Any process that activates or increases the frequency, rate or extent of testosterone secretion.	got7fsn_ti							bf	2011-07-26T08:42:36Z						biological_process											owl:Class	
UBERON:0002370	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000842	biolink:NamedThing	positive regulation of dehydroepiandrosterone secretion	Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion.	got7fsn_ti	positive regulation of dehydroisoandrosterone secretion|positive regulation of DHEA secretion|positive regulation of 3beta-hydroxyandrost-5-en-17-one secretion						bf	2011-07-26T08:41:36Z						biological_process											owl:Class	
GO:2000760	biolink:NamedThing	negative regulation of N-terminal peptidyl-lysine acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.	got7fsn_ti							yaf	2011-06-17T12:58:20Z						biological_process											owl:Class	
GO:0071663	biolink:NamedThing	positive regulation of granzyme B production	Any process that activates or increases the frequency, rate, or extent of production of granzyme B.	got7fsn_ti							mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:1900626	biolink:NamedThing	regulation of arugosin biosynthetic process	Any process that modulates the frequency, rate or extent of arugosin biosynthetic process.	got7fsn_ti	regulation of arugosin synthesis|regulation of arugosin formation|regulation of arugosin anabolism|regulation of arugosin biosynthesis						di	2012-05-21T05:47:39Z						biological_process											owl:Class	
GO:0019750	biolink:NamedThing	chloroplast localization	Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants.	got7fsn_ti	chloroplast localisation													biological_process											owl:Class	
GO:0010616	biolink:NamedThing	negative regulation of cardiac muscle adaptation	Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.	got7fsn_ti														biological_process											owl:Class	
GO:0009810	biolink:NamedThing	stilbene metabolic process	The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA.	got7fsn_ti	stilbene metabolism													biological_process											owl:Class	
GO:0039589	biolink:NamedThing	obsolete suppression by virus of host TAP complex	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TAP complex, a heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). The TAP complex functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum, where they are loaded onto the MHC class I. By inhibiting the TAP complex, the virus prevents viral particles being presented at the cell surface, and thus evades the host immune response.	got7fsn_ti	inhibition of host TAP by virus				This term was obsoleted because this type of process is now represented by the actual function inhibited.	GO:0039588	bf	2012-06-22T14:42:06Z		True		VZ:817		biological_process											owl:Class	
GO:0051140	biolink:NamedThing	regulation of NK T cell proliferation	Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.	got7fsn_ti	regulation of natural T cell proliferation|regulation of NK T-cell proliferation|regulation of NK T lymphocyte proliferation|regulation of NK T-lymphocyte proliferation|regulation of NKT cell proliferation|regulation of natural killer T cell proliferation|regulation of NT cell proliferation													biological_process											owl:Class	
GO:0075288	biolink:NamedThing	negative regulation of sporangiospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.	got7fsn_ti														biological_process											owl:Class	
PR:000000034	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075044	biolink:NamedThing	positive regulation by symbiont of host autophagy	Any process in which a symbiont organism increases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host autophagotic process|autophagy of host cells during interaction with symbiont|autophagy of host cells involved in interaction with symbiont													biological_process											owl:Class	
GO:0046063	biolink:NamedThing	dCMP metabolic process	The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate.	got7fsn_ti	dCMP metabolism													biological_process											owl:Class	
GO:1901419	biolink:NamedThing	regulation of response to alcohol	Any process that modulates the frequency, rate or extent of response to alcohol.	got7fsn_ti							tt	2012-10-01T16:52:13Z						biological_process											owl:Class	
IAO:0000233	biolink:NamedThing	term tracker item		got7fsn_ti												IAO:0000233		external	True	True							term_tracker_item		owl:AnnotationProperty	
GO:0150142	biolink:NamedThing	positive regulation of CD86 production	Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process.	got7fsn_ti	positive regulation of CD86 biosynthetic process						bc	2019-12-08T09:35:35Z						biological_process											owl:Class	
GO:0120194	biolink:NamedThing	regulation of anther dehiscence	Any process involved in the dehiscence of an anther to release the pollen grains contained within it.	got7fsn_ti							krc	2019-04-09T21:40:39Z						biological_process											owl:Class	
GO:1901118	biolink:NamedThing	cephamycin C biosynthetic process	The chemical reactions and pathways resulting in the formation of cephamycin C.	got7fsn_ti	cephamycin C anabolism|cephamycin C synthesis|cephamycin C formation|cephamycin C biosynthesis						yaf	2012-07-11T03:07:21Z						biological_process											owl:Class	
GO:0075264	biolink:NamedThing	regulation of oogonium development	Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.	got7fsn_ti														biological_process											owl:Class	
GO:0071273	biolink:NamedThing	morphine catabolic process	The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.	got7fsn_ti	morphine degradation|morphine breakdown|morphine catabolism						mah	2009-12-10T11:16:28Z				UniPathway:Q02198		biological_process											owl:Class	
GO:0051418	biolink:NamedThing	microtubule nucleation by microtubule organizing center	The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.	got7fsn_ti	microtubule nucleation by MTOC|MTOC-mediated microtubule nucleation|microtubule organizing center-mediated microtubule nucleation|microtubule nucleation by microtubule organising centre													biological_process											owl:Class	
GO:1901733	biolink:NamedThing	quercetin catabolic process	The chemical reactions and pathways resulting in the breakdown of quercetin.	got7fsn_ti	quercetin breakdown|quercetin degradation|quercetin catabolism						yaf	2013-01-11T10:25:15Z						biological_process											owl:Class	
GO:0015001	biolink:NamedThing	obsolete high-potential iron-sulfur carrier	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	high-potential iron-sulfur carrier|HiPIP|high-potential iron-sulphur carrier			GO:0009055	This term was made obsolete because it refers to a class of gene products.					True				molecular_function											owl:Class	
GO:0044591	biolink:NamedThing	response to amylopectin	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus.	got7fsn_ti							jl	2012-04-26T03:20:03Z						biological_process											owl:Class	
GO:0003928	biolink:NamedThing	obsolete RAB small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	RAB small monomeric GTPase activity			GO:0003924	This term was made obsolete because it represents a gene product.	GO:0016192|GO:0016191				True				molecular_function											owl:Class	
GO:0060731	biolink:NamedThing	positive regulation of intestinal epithelial structure maintenance	Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.	got7fsn_ti							dph	2009-06-12T01:51:50Z						biological_process											owl:Class	
GO:1900497	biolink:NamedThing	regulation of butyryl-CoA catabolic process to butanol	Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol.	got7fsn_ti	regulation of butyryl-CoA catabolism to butanol						tt	2012-05-02T03:53:20Z						biological_process											owl:Class	
GO:0032546	biolink:NamedThing	deoxyribonucleoside binding	Binding to a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.	got7fsn_ti														molecular_function											owl:Class	
GO:0009911	biolink:NamedThing	positive regulation of flower development	Any process that activates or increases the frequency, rate or extent of flower development.	got7fsn_ti	stimulation of flower development|upregulation of flower development|activation of flower development|up-regulation of flower development|up regulation of flower development													biological_process											owl:Class	
GO:0031494	biolink:NamedThing	regulation of mating type switching	Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.	got7fsn_ti														biological_process											owl:Class	
GO:0043435	biolink:NamedThing	response to corticotropin-releasing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.	got7fsn_ti	response to corticoliberin stimulus|response to corticotropin-releasing factor stimulus|response to CRF stimulus|response to corticotropin-releasing hormone stimulus|response to CRH stimulus													biological_process											owl:Class	
CHEBI:354984	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042192	biolink:NamedThing	methylmercury biosynthetic process	The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal.	got7fsn_ti	methylmercury biosynthesis|methylmercury anabolism|methylmercury formation|methylmercury synthesis													biological_process											owl:Class	
GO:1903546	biolink:NamedThing	protein localization to photoreceptor outer segment	A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment.	got7fsn_ti	protein localization in photoreceptor outer segment|protein localisation to photoreceptor outer segment|protein localisation in photoreceptor outer segment						krc	2014-10-17T21:14:11Z						biological_process											owl:Class	
CHEBI:17578	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042190	biolink:NamedThing	vanillin catabolic process	The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.	got7fsn_ti	vanillic aldehyde catabolism|vanillin catabolism|vanillic aldehyde catabolic process|vanillin degradation|vanillin breakdown													biological_process											owl:Class	
GO:1900330	biolink:NamedThing	regulation of methane biosynthetic process from trimethylamine	Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine.	got7fsn_ti							tt	2012-04-06T01:53:03Z						biological_process											owl:Class	
GO:0005985	biolink:NamedThing	sucrose metabolic process	The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside.	got7fsn_ti	sucrose metabolism													biological_process											owl:Class	
GO:1901421	biolink:NamedThing	positive regulation of response to alcohol	Any process that activates or increases the frequency, rate or extent of response to alcohol.	got7fsn_ti	upregulation of response to alcohol|up regulation of response to alcohol|activation of response to alcohol|up-regulation of response to alcohol						tt	2012-10-01T16:53:42Z						biological_process											owl:Class	
GO:0052516	biolink:NamedThing	obsolete positive regulation by organism of symbiont jasmonic acid-mediated defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	induction by organism of symbiont jasmonic acid-mediated defense response|positive regulation by organism of symbiont JA-mediated defense response|induction by organism of symbiont JA-mediated defense response|positive regulation by organism of symbiont jasmonic acid-mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0015355	biolink:NamedThing	secondary active monocarboxylate transmembrane transporter activity	Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism.	got7fsn_ti	monocarboxylate porter activity													molecular_function											owl:Class	
GO:0100019	biolink:NamedThing	obsolete regulation of cAMP-mediated signaling by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cAMP-mediated signaling.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14279			The reason for obsoletion is that cAMP-mediated signaling is not mediated by transcription from RNA polII promoter.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
OIO:created_by	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
GO:0002657	biolink:NamedThing	positive regulation of tolerance induction to nonself antigen	Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.	got7fsn_ti	activation of tolerance induction to nonself antigen|up regulation of tolerance induction to nonself antigen|stimulation of tolerance induction to nonself antigen|up-regulation of tolerance induction to nonself antigen|upregulation of tolerance induction to nonself antigen													biological_process											owl:Class	
GO:0140124	biolink:NamedThing	positive regulation of Lewy body formation	Any process that activates or increases the frequency, rate or extent of Lewy body formation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14160					pg	2017-10-25T07:10:14Z						biological_process											owl:Class	
GO:0043646	biolink:NamedThing	cephalosporin biosynthetic process	The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.	got7fsn_ti														biological_process											owl:Class	
GO:0046874	biolink:NamedThing	quinolinate metabolic process	The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.	got7fsn_ti	quinolinate metabolism													biological_process											owl:Class	
CHEBI:28897	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052464	biolink:NamedThing	obsolete modulation by organism of symbiont programmed cell death	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont programmed cell death|modulation of symbiont PCD|modulation of symbiont HR|modulation of symbiont hypersensitive response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1905901	biolink:NamedThing	positive regulation of smooth muscle tissue development	Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development.	got7fsn_ti	activation of smooth muscle tissue development|upregulation of smooth muscle tissue development|up-regulation of smooth muscle tissue development|up regulation of smooth muscle tissue development						bhm	2017-02-01T14:31:33Z						biological_process											owl:Class	
GO:0075046	biolink:NamedThing	positive regulation of formation by symbiont of haustorium for nutrient acquisition from host	Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
GO:0100041	biolink:NamedThing	obsolete positive regulation of pseudohyphal growth by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pseudohyphal growth.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0048196	biolink:NamedThing	obsolete plant extracellular matrix	OBSOLETE. The matrix external to the plant plasma membrane, composed of the cell wall and middle lamella.	got7fsn_ti	plant extracellular matrix|middle lamella-containing extracellular matrix				Note that this term does not have 'extracellular region ; GO:0005576' as a parent because in plants the extracellular matrix is considered part of the cell.					True				cellular_component											owl:Class	
GO:0002550	biolink:NamedThing	positive regulation of plasma kallikrein-kinin cascade	Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade.	got7fsn_ti	upregulation of plasma kallikrein-kinin cascade|stimulation of plasma kallikrein-kinin cascade|up regulation of plasma kallikrein-kinin cascade|up-regulation of plasma kallikrein-kinin cascade|activation of plasma kallikrein-kinin cascade													biological_process											owl:Class	
GO:0071913	biolink:NamedThing	citrate secondary active transmembrane transporter activity	Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	citrate carrier activity						mah	2010-09-22T02:18:54Z						molecular_function											owl:Class	
GO:0033623	biolink:NamedThing	regulation of integrin activation	Any process that modulates the frequency, rate, or extent of integrin activation.	got7fsn_ti	regulation of integrin complex activation													biological_process											owl:Class	
GO:1901124	biolink:NamedThing	bacitracin A biosynthetic process	The chemical reactions and pathways resulting in the formation of bacitracin A.	got7fsn_ti	bacitracin A anabolism|bacitracin A formation|bacitracin A synthesis|bacitracin A biosynthesis						yaf	2012-07-11T03:16:27Z						biological_process											owl:Class	
GO:0015401	biolink:NamedThing	urea:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in).	got7fsn_ti	urea active transmembrane transporter activity													molecular_function											owl:Class	
GO:0035340	biolink:NamedThing	inosine transport	The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	hypoxanthine riboside transport						bf	2010-03-04T10:00:58Z						biological_process											owl:Class	
GO:0002889	biolink:NamedThing	regulation of immunoglobulin mediated immune response	Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.	got7fsn_ti														biological_process											owl:Class	
GO:0043371	biolink:NamedThing	negative regulation of CD4-positive, alpha-beta T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.	got7fsn_ti	down-regulation of CD4-positive, alpha beta T cell differentiation|downregulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive T-cell differentiation|negative regulation of CD4-positive, alpha beta T cell development|inhibition of CD4-positive, alpha beta T cell differentiation|down regulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T lymphocyte differentiation|negative regulation of CD4-positive, alpha beta T-cell differentiation|negative regulation of CD4-positive T-lymphocyte differentiation|negative regulation of CD4-positive, alpha beta T-lymphocyte differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0050938	biolink:NamedThing	regulation of xanthophore differentiation	Any process that modulates the frequency, rate or extent of xanthophore differentiation.	got7fsn_ti					Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure.									biological_process											owl:Class	
GO:0002827	biolink:NamedThing	positive regulation of T-helper 1 type immune response	Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.	got7fsn_ti	stimulation of T-helper 1 type immune response|activation of T-helper 1 type immune response|upregulation of T-helper 1 type immune response|up-regulation of T-helper 1 type immune response|up regulation of T-helper 1 type immune response													biological_process											owl:Class	
GO:0090091	biolink:NamedThing	positive regulation of extracellular matrix disassembly	Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.	got7fsn_ti							tb	2009-11-04T10:03:25Z						biological_process											owl:Class	
GO:0007607	biolink:NamedThing	obsolete taste perception	OBSOLETE. The series of events required for the chemical composition of a soluble stimulus to be received and converted to a molecular signal.	got7fsn_ti	taste perception				This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage.	GO:0050912|GO:0050909				True				biological_process											owl:Class	
GO:2000352	biolink:NamedThing	negative regulation of endothelial cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.	got7fsn_ti	negative regulation of apoptosis of endothelial cells|negative regulation of programmed cell death, endothelial cells|negative regulation of killing of endothelial cells|negative regulation of programmed cell death of endothelial cells by apoptosis|negative regulation of endothelial cell apoptosis|negative regulation of endothelial cell programmed cell death by apoptosis						mah	2011-02-03T10:43:20Z						biological_process											owl:Class	
GO:1900894	biolink:NamedThing	negative regulation of tridecane metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process.	got7fsn_ti	down-regulation of tridecane metabolism|inhibition of tridecane metabolic process|negative regulation of tridecane metabolism|downregulation of tridecane metabolism|down regulation of tridecane metabolism|down-regulation of tridecane metabolic process|inhibition of tridecane metabolism|downregulation of tridecane metabolic process|down regulation of tridecane metabolic process						tt	2012-06-13T03:15:03Z						biological_process											owl:Class	
GO:1905580	biolink:NamedThing	positive regulation of ERBB3 signaling pathway	Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway.	got7fsn_ti	positive regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up regulation of HER3 signaling pathway|activation of HER3 signaling pathway|up-regulation of ERBB3 signaling pathway|upregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|activation of ERBB3 signalling pathway|upregulation of ERBB3 signalling pathway|activation of receptor tyrosine-protein kinase erbB-3 signaling pathway|positive regulation of HER3 signaling pathway|up regulation of ERBB3 signalling pathway|up-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up regulation of ERBB3 signaling pathway|upregulation of HER3 signaling pathway|activation of ERBB3 signaling pathway|up-regulation of ERBB3 signalling pathway|up-regulation of HER3 signaling pathway|positive regulation of ERBB3 signalling pathway|upregulation of ERBB3 signaling pathway						als	2016-10-19T11:47:11Z						biological_process											owl:Class	
GO:1905200	biolink:NamedThing	gibberellic acid transmembrane transport	The directed movement of gibberellic acid across a membrane.	got7fsn_ti							lr	2016-05-12T18:20:04Z						biological_process											owl:Class	
GO:0070961	biolink:NamedThing	positive regulation of neutrophil mediated killing of symbiont cell	Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.	got7fsn_ti	activation of neutrophil mediated killing of symbiont cell|upregulation of neutrophil mediated killing of symbiont cell|up-regulation of neutrophil mediated killing of symbiont cell|up regulation of neutrophil mediated killing of symbiont cell|stimulation of neutrophil mediated killing of symbiont cell						mah	2009-10-01T02:28:49Z						biological_process											owl:Class	
GO:2000098	biolink:NamedThing	negative regulation of smooth muscle cell-matrix adhesion	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion.	got7fsn_ti							dph	2010-09-14T04:22:22Z						biological_process											owl:Class	
GO:1905839	biolink:NamedThing	negative regulation of telomeric D-loop disassembly	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly.	got7fsn_ti	down-regulation of telomeric D-loop disassembly|down regulation of telomeric D-loop disassembly|downregulation of telomeric D-loop disassembly|inhibition of telomeric D-loop disassembly						nc	2017-01-18T11:01:47Z						biological_process											owl:Class	
GO:0009394	biolink:NamedThing	2'-deoxyribonucleotide metabolic process	The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	2'-deoxyribonucleotide metabolism													biological_process											owl:Class	
GO:0070954	biolink:NamedThing	negative regulation of neutrophil mediated cytotoxicity	Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.	got7fsn_ti	down regulation of neutrophil mediated cytotoxicity|inhibition of neutrophil mediated cytotoxicity|down-regulation of neutrophil mediated cytotoxicity|downregulation of neutrophil mediated cytotoxicity|negative regulation of neutrophil mediated cell killing						mah	2009-10-01T02:20:17Z						biological_process											owl:Class	
GO:1903630	biolink:NamedThing	regulation of aminoacyl-tRNA ligase activity	Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity.	got7fsn_ti	regulation of aminoacyl-tRNA synthetase auxiliary protein activity|regulation of aminoacyl-tRNA synthetase activity						sl	2014-11-20T00:22:04Z						biological_process											owl:Class	
GO:0030074	biolink:NamedThing	obsolete thylakoid (sensu Proteobacteria)	OBSOLETE. A thylakoid; as in, but not restricted to, the purple bacteria and relatives (Proteobacteria, ncbi_taxonomy_id:1224).	got7fsn_ti	thylakoid (sensu Proteobacteria)				This term was made obsolete because thylakoids are not found in organisms of the Phylum Proteobacteria.	GO:0042716				True				cellular_component											owl:Class	
GO:1902277	biolink:NamedThing	negative regulation of pancreatic amylase secretion	Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion.	got7fsn_ti	inhibition of pancreatic amylase secretion|down regulation of pancreatic amylase secretion|downregulation of pancreatic amylase secretion|down-regulation of pancreatic amylase secretion						bf	2013-07-03T12:15:26Z						biological_process											owl:Class	
GO:0050799	biolink:NamedThing	cocaine biosynthetic process	The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.	got7fsn_ti	cocaine anabolism|cocaine formation|cocaine synthesis|cocaine biosynthesis													biological_process											owl:Class	
GO:0051184	biolink:NamedThing	obsolete cofactor transmembrane transporter activity	OBSOLETE. Enables the transfer of a cofactor from one side of a membrane to the other. A cofactor is a substance that is required for the activity of an enzyme or other protein.	got7fsn_ti	cofactor transporter activity|vitamin or cofactor transporter activity				1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a cofactor.					True				molecular_function											owl:Class	
GO:1904917	biolink:NamedThing	L-arginine transmembrane transport from lysosomal lumen to cytosol	The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol.	got7fsn_ti	transmembrane L-arginine transport from lysosomal lumen to cytosol						kmv	2016-01-21T16:27:48Z						biological_process											owl:Class	
GO:0052411	biolink:NamedThing	obsolete metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism by organism of cell wall chitin in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0106180	biolink:NamedThing	obsolete translocase activty of hydrons	OBSOLETE. Catalysis of the translocation of hydrons (hydron being the general name for H+ in its natural abundance).	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:48:44Z		True		EC:7.1.-.-		molecular_function											owl:Class	
GO:0052407	biolink:NamedThing	obsolete metabolism by organism of carbohydrate in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism by organism of carbohydrate in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
CHEBI:26421	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010897	biolink:NamedThing	negative regulation of triglyceride catabolic process	Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.	got7fsn_ti	negative regulation of triacylglycerol catabolic process													biological_process											owl:Class	
GO:0045612	biolink:NamedThing	positive regulation of hemocyte differentiation	Any process that activates or increases the frequency, rate or extent of hemocyte differentiation.	got7fsn_ti	up-regulation of hemocyte differentiation|stimulation of hemocyte differentiation|upregulation of hemocyte differentiation|up regulation of hemocyte differentiation|positive regulation of arthropod blood cell differentiation|activation of hemocyte differentiation													biological_process											owl:Class	
GO:0072301	biolink:NamedThing	regulation of metanephric glomerular mesangial cell proliferation	Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.	got7fsn_ti							mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
GO:0036270	biolink:NamedThing	response to diuretic	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T01:26:24Z						biological_process											owl:Class	
GO:0005429	biolink:NamedThing	obsolete chromaffin granule amine transmembrane transporter activity	OBSOLETE. Enables the transfer of amines across chromaffin granule membranes.	got7fsn_ti					The term was obsoleted because its intended usage was unclear: chromaffin granules are dense core secretory vesicles (PMID:20853344) so whatever they transport must be by secretion.					True				molecular_function											owl:Class	
GO:0036523	biolink:NamedThing	obsolete induction by symbiont of host cytokine production	OBSOLETE. Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host cytokine secretion|'induction by symbiont of host cytokine secretion'|induction by symbiont of host cytokine secretion	https://github.com/geneontology/go-ontology/issues/21743			This term was obsoleted because it does not represent a real process.		bf	2016-06-06T14:53:54Z		True				biological_process											owl:Class	
GO:0090191	biolink:NamedThing	negative regulation of branching involved in ureteric bud morphogenesis	Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	got7fsn_ti							tb	2009-12-18T11:11:17Z						biological_process											owl:Class	
PR:000001590	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903801	biolink:NamedThing	L-leucine import across plasma membrane	The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	leucine import|leucine uptake|L-leucine import|L-leucine import into cell|L-leucine uptake						mah	2015-01-16T14:34:46Z			GO:0060356			biological_process											owl:Class	
GO:2000359	biolink:NamedThing	regulation of binding of sperm to zona pellucida	Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida.	got7fsn_ti	regulation of ZPG binding						yaf	2011-02-03T02:42:50Z						biological_process											owl:Class	
GO:0042804	biolink:NamedThing	obsolete protein homooligomerization activity	OBSOLETE. Interacting selectively with identical proteins to form a homooligomer.	got7fsn_ti	protein homooligomerization activity|oligomerization activity			GO:0051260	This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:0051869	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071332	biolink:NamedThing	cellular response to fructose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.	got7fsn_ti							mah	2009-12-10T05:37:39Z						biological_process											owl:Class	
GO:0060623	biolink:NamedThing	regulation of chromosome condensation	Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.	got7fsn_ti							dph	2009-05-18T02:12:13Z						biological_process											owl:Class	
GO:0090703	biolink:NamedThing	obsolete triplex DNA unwinding	OBSOLETE. The process by which a three-stranded D-loop DNA is unwound or 'melted'.	got7fsn_ti					This term was made obsolete because it was created in error.		tb	2016-09-20T16:37:15Z		True				biological_process											owl:Class	
GO:1905153	biolink:NamedThing	regulation of membrane invagination	Any process that modulates the frequency, rate or extent of membrane invagination.	got7fsn_ti							bf	2016-04-18T15:43:54Z						biological_process											owl:Class	
GO:0031933	biolink:NamedThing	obsolete telomeric heterochromatin	OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres.	got7fsn_ti	telomeric chromatin	https://github.com/geneontology/go-ontology/issues/19086			This term was obsoleted because there is no heterochromatin at the telomere and the term had been used inconsistently.					True				cellular_component											owl:Class	
GO:1904286	biolink:NamedThing	negative regulation of protein-pyridoxal-5-phosphate linkage	Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.	got7fsn_ti	downregulation of protein-pyridoxal-5-phosphate linkage|down regulation of protein-pyridoxal-5-phosphate linkage|inhibition of protein-pyridoxal-5-phosphate linkage|down-regulation of protein-pyridoxal-5-phosphate linkage						mcc	2015-06-05T17:21:21Z						biological_process											owl:Class	
GO:0031455	biolink:NamedThing	glycine betaine metabolic process	The chemical reactions and pathways involving glycine betaine, N-trimethylglycine.	got7fsn_ti	N-trimethylglycine metabolism|N-trimethylglycine metabolic process|glycine betaine metabolism													biological_process											owl:Class	
GO:1901834	biolink:NamedThing	regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.	got7fsn_ti	regulation of deadenylation-independent decapping of nuclear mRNA|regulation of deadenylylation-independent decapping						al	2013-01-22T22:42:17Z						biological_process											owl:Class	
GO:0034106	biolink:NamedThing	regulation of erythrocyte clearance	Any process that modulates the frequency, rate, or extent of erythrocyte clearance.	got7fsn_ti	regulation of neocytolysis|regulation of RBC clearance|regulation of red blood cell clearance													biological_process											owl:Class	
GO:0045020	biolink:NamedThing	obsolete error-prone DNA repair	OBSOLETE. DNA repair pathways that tend to increase the endogenous mutation rate.	got7fsn_ti	error-prone DNA repair|mutagenic DNA repair				This term was made obsolete because 'error-prone' does not correspond to a repair mechanism, and the term has been superseded by more specific terms.	GO:0042276				True				biological_process											owl:Class	
GO:1904505	biolink:NamedThing	regulation of telomere maintenance in response to DNA damage	Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage.	got7fsn_ti	regulation of DNA damage response, telomere maintenance						nc	2015-07-24T16:05:55Z						biological_process											owl:Class	
GO:0005208	biolink:NamedThing	obsolete amyloid protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	amyloid protein				This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1900428	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms.	got7fsn_ti							di	2012-04-25T05:53:33Z						biological_process											owl:Class	
GO:0033576	biolink:NamedThing	protein glycosylation in cytosol	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol.	got7fsn_ti	protein amino acid glycosylation in cytosol													biological_process											owl:Class	
GO:0019131	biolink:NamedThing	obsolete tripeptidyl-peptidase I activity	OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide; requires acid pH.	got7fsn_ti	tripeptidyl aminopeptidase activity|tripeptidyl peptidase activity|tripeptidyl-peptidase I activity			GO:0008240	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0032383	biolink:NamedThing	regulation of intracellular cholesterol transport	Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.	got7fsn_ti														biological_process											owl:Class	
GO:0033469	biolink:NamedThing	gibberellin 12 metabolic process	The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.	got7fsn_ti	gibberellin A12 metabolic process|GA12 metabolic process|gibberellin 12 metabolism													biological_process											owl:Class	
GO:0150178	biolink:NamedThing	regulation of phosphatidylserine metabolic process	Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process.	got7fsn_ti							bc	2020-01-21T14:05:21Z						biological_process											owl:Class	
UBERON:0010183	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010832	biolink:NamedThing	negative regulation of myotube differentiation	Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	got7fsn_ti														biological_process											owl:Class	
GO:0101019	biolink:NamedThing	nucleolar exosome (RNase complex)	A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.	got7fsn_ti							bhm							cellular_component											owl:Class	
CHEBI:58145	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0080113	biolink:NamedThing	regulation of seed growth	Any process that modulates the frequency, rate or extent of growth of the seed of an plant.	got7fsn_ti	regulation of seed size						dhl	2009-04-27T02:55:01Z						biological_process											owl:Class	
UBERON:0000988	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000024	biolink:NamedThing	maltose biosynthetic process	The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).	got7fsn_ti	maltose synthesis|maltose formation|maltose biosynthesis|maltose anabolism|malt sugar biosynthesis|malt sugar biosynthetic process													biological_process											owl:Class	
GO:1901946	biolink:NamedThing	miltiradiene biosynthetic process	The chemical reactions and pathways resulting in the formation of miltiradiene.	got7fsn_ti	miltiradiene anabolism|miltiradiene synthesis|miltiradiene biosynthesis|miltiradiene formation						ms	2013-02-18T15:50:32Z						biological_process											owl:Class	
GO:1900960	biolink:NamedThing	negative regulation of 17-methylnonadec-1-ene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.	got7fsn_ti	down regulation of 17-methylnonadec-1-ene metabolism|inhibition of 17-methylnonadec-1-ene metabolism|inhibition of 17-methylnonadec-1-ene metabolic process|downregulation of 17-methylnonadec-1-ene metabolism|down regulation of 17-methylnonadec-1-ene metabolic process|down-regulation of 17-methylnonadec-1-ene metabolic process|negative regulation of 17-methylnonadec-1-ene metabolism|down-regulation of 17-methylnonadec-1-ene metabolism|downregulation of 17-methylnonadec-1-ene metabolic process						tt	2012-06-14T03:29:51Z						biological_process											owl:Class	
CHEBI:18035	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044141	biolink:NamedThing	obsolete negative regulation of development of symbiont on or near host surface	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	got7fsn_ti					The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-04T04:32:18Z		True				biological_process											owl:Class	
GO:0036045	biolink:NamedThing	obsolete peptidyl-lysine malonylation	OBSOLETE. The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.	got7fsn_ti	lysine malonylation|peptidyl-lysine malonylation			GO:0044392	This term was made obsolete because it accidentally reused an exisiting id. See replacement term GO:0044392.		bf	2011-12-12T09:31:42Z		True				biological_process											owl:Class	
GO:0002659	biolink:NamedThing	negative regulation of peripheral tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.	got7fsn_ti	inhibition of peripheral tolerance induction|downregulation of peripheral tolerance induction|down-regulation of peripheral tolerance induction|down regulation of peripheral tolerance induction													biological_process											owl:Class	
GO:1904569	biolink:NamedThing	regulation of selenocysteine incorporation	Any process that modulates the frequency, rate or extent of selenocysteine incorporation.	got7fsn_ti							sl	2015-08-19T17:26:38Z						biological_process											owl:Class	
GO:0075339	biolink:NamedThing	obsolete positive regulation of growth or development of symbiont during interaction with host	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	got7fsn_ti	positive regulation of growth or development of symbiont during interaction with host				This term was made obsolete because it contained a conjunction (or).					True				biological_process											owl:Class	
GO:0046071	biolink:NamedThing	dGTP biosynthetic process	The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate.	got7fsn_ti	dGTP formation|dGTP synthesis|dGTP biosynthesis|dGTP anabolism													biological_process											owl:Class	
GO:0030664	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902004	biolink:NamedThing	positive regulation of amyloid-beta formation	Any process that activates or increases the frequency, rate or extent of amyloid-beta formation.	got7fsn_ti	up regulation of beta-amyloid formation|activation of beta-amyloid formation|up-regulation of beta-amyloid formation|upregulation of beta-amyloid formation|positive regulation of beta-amyloid formation						dph	2013-03-21T19:59:31Z						biological_process											owl:Class	
GO:1990543	biolink:NamedThing	mitochondrial S-adenosyl-L-methionine transmembrane transport	The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T11:26:27Z						biological_process											owl:Class	
GO:1905676	biolink:NamedThing	positive regulation of adaptive immune memory response	Any process that activates or increases the frequency, rate or extent of adaptive immune memory response.	got7fsn_ti	up-regulation of adaptive immune memory response|upregulation of adaptive immune memory response|activation of adaptive immune memory response|up regulation of adaptive immune memory response						tb	2016-11-11T22:24:49Z						biological_process											owl:Class	
GO:0043400	biolink:NamedThing	cortisol secretion	The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.	got7fsn_ti	hydrocortisone secretion													biological_process											owl:Class	
GO:1900752	biolink:NamedThing	malonic acid transport	The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	HOOC-CH2-COOH transport|C3H4O4 transport|propanedioic acid transport|H2malo transport						jl	2012-05-29T02:40:33Z						biological_process											owl:Class	
GO:0046127	biolink:NamedThing	pyrimidine deoxyribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	pyrimidine deoxyribonucleoside degradation|pyrimidine deoxyribonucleoside breakdown|pyrimidine deoxyribonucleoside catabolism													biological_process											owl:Class	
GO:0097040	biolink:NamedThing	phthiocerol biosynthetic process	The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents.	got7fsn_ti	phthiocerol synthesis|phthiocerol biosynthesis|phthiocerol formation|phthiocerol anabolism						pr	2011-04-15T01:18:17Z						biological_process											owl:Class	
GO:0022854	biolink:NamedThing	obsolete active large uncharged polar molecule transmembrane transporter activity	OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.	got7fsn_ti	active large uncharged polar molecule transmembrane transporter activity			GO:0022804	This term was made obsolete because 'large uncharged polar molecule' is not a useful chemical grouping term.					True				molecular_function											owl:Class	
GO:1905336	biolink:NamedThing	negative regulation of aggrephagy	Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy.	got7fsn_ti	downregulation of aggrephagy|down regulation of aggrephagy|down-regulation of aggrephagy|inhibition of aggrephagy						pad	2016-07-26T13:41:54Z						biological_process											owl:Class	
GO:2000295	biolink:NamedThing	regulation of hydrogen peroxide catabolic process	Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process.	got7fsn_ti	regulation of hydrogen peroxide degradation|regulation of hydrogen peroxide removal|regulation of H2O2 scavenging|regulation of hydrogen peroxide catabolism|regulation of hydrogen peroxide breakdown|regulation of H2O2 catabolic process|regulation of detoxification of H2O2|regulation of hydrogen peroxide scavenging|regulation of detoxification of hydrogen peroxide						rl	2010-12-21T03:30:51Z						biological_process											owl:Class	
GO:0045071	biolink:NamedThing	negative regulation of viral genome replication	Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.	got7fsn_ti	inhibition of viral genome replication|down-regulation of viral genome replication|downregulation of viral genome replication|down regulation of viral genome replication													biological_process											owl:Class	
GO:0046380	biolink:NamedThing	N-acetylneuraminate biosynthetic process	The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.	got7fsn_ti	N-acetylneuraminate anabolism|N-acetylneuraminate synthesis|N-acetylneuraminate formation|N-acetylneuraminate biosynthesis													biological_process											owl:Class	
GO:1903692	biolink:NamedThing	methionine import across plasma membrane	The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	methionine import into cell|methionine import						jl	2012-08-15T14:54:38Z			GO:0044690			biological_process											owl:Class	
GO:0080040	biolink:NamedThing	positive regulation of cellular response to phosphate starvation	Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation.	got7fsn_ti														biological_process											owl:Class	
GO:2000048	biolink:NamedThing	negative regulation of cell-cell adhesion mediated by cadherin	Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin.	got7fsn_ti							jl	2010-08-20T12:56:51Z						biological_process											owl:Class	
GO:0002877	biolink:NamedThing	regulation of acute inflammatory response to non-antigenic stimulus	Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0062231	biolink:NamedThing	positive regulation of larval somatic muscle development	Any process that increases the rate, frequency or extent of larval somatic muscle development.	got7fsn_ti							dph	2020-03-16T13:49:16Z						biological_process											owl:Class	
GO:0098919	biolink:NamedThing	structural constituent of postsynaptic density	The action of a molecule that contributes to the structural integrity of a postsynaptic density.	got7fsn_ti														molecular_function											owl:Class	
GO:0004728	biolink:NamedThing	obsolete signal transducer, downstream of receptor, with protein tyrosine phosphatase activity	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	got7fsn_ti	receptor signalling protein tyrosine phosphatase activity|receptor signaling protein tyrosine phosphatase activity	https://github.com/geneontology/go-ontology/issues/14232			This term was obsoleted because it was not clearly defined.					True				molecular_function											owl:Class	
GO:0075233	biolink:NamedThing	obsolete negative regulation of spore movement on or near host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:1901532	biolink:NamedThing	regulation of hematopoietic progenitor cell differentiation	Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation.	got7fsn_ti	regulation of hemopoietic progenitor cell differentiation|regulation of haemopoietic progenitor cell differentiation|regulation of haematopoietic progenitor cell differentiation						vk	2012-10-24T11:23:01Z						biological_process											owl:Class	
GO:0048293	biolink:NamedThing	regulation of isotype switching to IgE isotypes	Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.	got7fsn_ti	regulation of isotype switch recombination to IgE isotypes|regulation of class switching to IgE isotypes|regulation of class switch recombination to IgE isotypes													biological_process											owl:Class	
GO:1901220	biolink:NamedThing	negative regulation of cardiac chamber morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis.	got7fsn_ti	inhibition of cardiac chamber morphogenesis|down regulation of heart chamber morphogenesis|inhibition of heart chamber morphogenesis|down-regulation of heart chamber morphogenesis|negative regulation of heart chamber morphogenesis|down-regulation of cardiac chamber morphogenesis|down regulation of cardiac chamber morphogenesis|downregulation of heart chamber morphogenesis|downregulation of cardiac chamber morphogenesis						rl	2012-08-06T17:59:34Z						biological_process											owl:Class	
UBERON:0000459	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000556	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008427	biolink:NamedThing	calcium-dependent protein kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a calcium-dependent protein kinase.	got7fsn_ti														molecular_function											owl:Class	
GO:1905189	biolink:NamedThing	regulation of metaphase/anaphase transition of meiosis II	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II.	got7fsn_ti	regulation of meiosis II metaphase/anaphase transition						vw	2016-05-10T16:46:49Z						biological_process											owl:Class	
GO:1902567	biolink:NamedThing	negative regulation of eosinophil activation	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation.	got7fsn_ti	downregulation of eosinophil activation|down regulation of eosinophil activation|down-regulation of eosinophil activation|inhibition of eosinophil activation						ecu	2013-12-10T15:54:43Z						biological_process											owl:Class	
GO:0061434	biolink:NamedThing	obsolete regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction	OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging through a mechanism that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a caloric restriction stimulus.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0090398	dph	2012-02-09T09:06:09Z		True				biological_process											owl:Class	
GO:0097640	biolink:NamedThing	L-ornithine import across plasma membrane	The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-ornithine import into cell						pr	2014-09-03T09:48:14Z			GO:1903411			biological_process											owl:Class	
GO:0046376	biolink:NamedThing	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process	The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolism													biological_process											owl:Class	
GO:0046051	biolink:NamedThing	UTP metabolic process	The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate.	got7fsn_ti	UTP metabolism													biological_process											owl:Class	
GO:0035713	biolink:NamedThing	response to nitrogen dioxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.	got7fsn_ti	response to NO2						bf	2011-03-02T03:14:51Z						biological_process											owl:Class	
GO:1901282	biolink:NamedThing	fructoselysine biosynthetic process	The chemical reactions and pathways resulting in the formation of fructoselysine.	got7fsn_ti	fructosyllysine biosynthesis|fructosyllysine formation|fructosyllysine anabolism|fructosyllysine biosynthetic process|fructosyllysine synthesis						yaf	2012-08-17T15:05:05Z						biological_process											owl:Class	
GO:0015513	biolink:NamedThing	high-affinity secondary active nitrite transmembrane transporter activity	Catalysis of the transfer of nitrite from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	got7fsn_ti	nitrite uptake permease activity													molecular_function											owl:Class	
GO:0001402	biolink:NamedThing	signal transduction involved in filamentous growth	Relaying of environmental signals promoting filamentous growth.	got7fsn_ti	signal transduction during filamentous growth|MAPKKK cascade (pseudohyphal growth)													biological_process											owl:Class	
GO:0005395	biolink:NamedThing	obsolete eye pigment precursor transporter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out).	got7fsn_ti					This term has been obsoleted because eye pigment precursors are nucleotides and amino acids, and there are terms to annotate these functions.					True				molecular_function											owl:Class	
GO:1901610	biolink:NamedThing	positive regulation of vesicle transport along microtubule	Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.	got7fsn_ti	up regulation of microtubule-based vesicle localization|positive regulation of microtubule-based vesicle localization|activation of vesicle transport along microtubule|up-regulation of vesicle transport along microtubule|activation of microtubule-based vesicle localization|up-regulation of microtubule-based vesicle localization|up regulation of vesicle transport along microtubule|upregulation of microtubule-based vesicle localization|upregulation of vesicle transport along microtubule						hjd	2012-11-08T21:49:53Z						biological_process											owl:Class	
GO:0150172	biolink:NamedThing	regulation of phosphatidylcholine metabolic process	Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process.	got7fsn_ti							bc	2020-01-21T14:03:11Z						biological_process											owl:Class	
GO:0017141	biolink:NamedThing	obsolete antibiotic susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	antibiotic susceptibility/resistance			GO:0046677	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0019272	biolink:NamedThing	L-alanine biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.	got7fsn_ti	L-alanine synthesis from pyruvate|L-alanine formation from pyruvate|L-alanine anabolism from pyruvate											MetaCyc:ALANINE-VALINESYN-PWY|MetaCyc:ALANINE-SYN2-PWY		biological_process											owl:Class	
GO:0044822	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008393	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010530	biolink:NamedThing	positive regulation of transposition	Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.	got7fsn_ti														biological_process											owl:Class	
GO:0062099	biolink:NamedThing	negative regulation of programmed necrotic cell death	Any process that decreases the frequency, rate or extent of programmed necrotic cell death.	got7fsn_ti							dph	2018-11-29T15:05:56Z						biological_process											owl:Class	
GO:2001204	biolink:NamedThing	regulation of osteoclast development	Any process that modulates the frequency, rate or extent of osteoclast development.	got7fsn_ti	regulation of osteoclast cell development						yaf	2011-11-10T10:58:59Z						biological_process											owl:Class	
GO:1900328	biolink:NamedThing	negative regulation of mannotriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport.	got7fsn_ti	down regulation of mannotriose transport|downregulation of mannotriose transport|inhibition of mannotriose transport|down-regulation of mannotriose transport						tt	2012-04-06T01:50:13Z						biological_process											owl:Class	
GO:0045099	biolink:NamedThing	obsolete vimentin	OBSOLETE. A type of intermediate filament.	got7fsn_ti	vimentin			GO:0045098	This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
GO:1904757	biolink:NamedThing	positive regulation of gut granule assembly	Any process that activates or increases the frequency, rate or extent of gut granule assembly.	got7fsn_ti	upregulation of gut granule assembly|upregulation of gut granule biogenesis|up-regulation of gut granule formation|up-regulation of gut granule assembly|activation of gut granule assembly|up regulation of gut granule formation|up regulation of gut granule biogenesis|up-regulation of gut granule biogenesis|positive regulation of gut granule formation|activation of gut granule biogenesis|activation of gut granule formation|positive regulation of gut granule biogenesis|upregulation of gut granule formation|up regulation of gut granule assembly						ah	2015-10-21T08:43:57Z						biological_process											owl:Class	
GO:2001187	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta T cell activation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.	got7fsn_ti							yaf	2011-11-03T01:17:02Z						biological_process											owl:Class	
GO:1903441	biolink:NamedThing	protein localization to ciliary membrane	A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.	got7fsn_ti	protein localization in ciliary membrane|protein localisation to ciliary membrane|protein localisation in ciliary membrane						pr	2014-09-16T15:15:39Z						biological_process											owl:Class	
GO:0033073	biolink:NamedThing	pinene metabolic process	The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.	got7fsn_ti	pinene metabolism													biological_process											owl:Class	
GO:0034021	biolink:NamedThing	response to silicon dioxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.	got7fsn_ti	response to silox|response to silica													biological_process											owl:Class	
GO:1900067	biolink:NamedThing	regulation of cellular response to alkaline pH	Any process that modulates the frequency, rate or extent of cellular response to alkalinity.	got7fsn_ti	regulation of cellular response to alkalinity|regulation of cellular response to basic pH						pr	2012-01-26T02:34:59Z						biological_process											owl:Class	
GO:1901004	biolink:NamedThing	ubiquinone-6 metabolic process	The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.	got7fsn_ti	coenzyme Q6 metabolic process|coenzyme Q6 metabolism|ubiquinone-6 metabolism						bf	2012-06-15T09:59:28Z						biological_process											owl:Class	
GO:1904290	biolink:NamedThing	negative regulation of mitotic DNA damage checkpoint	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint.	got7fsn_ti	downregulation of mitotic DNA damage checkpoint|inhibition of mitotic DNA damage checkpoint|down regulation of mitotic DNA damage checkpoint|down-regulation of mitotic DNA damage checkpoint						kmv	2015-06-09T13:03:17Z						biological_process											owl:Class	
GO:1903256	biolink:NamedThing	selenoneine metabolic process	The chemical reactions and pathways involving selenoneine.	got7fsn_ti	selenoneine metabolism|L-selenoneine metabolic process						mah	2014-08-06T09:14:24Z						biological_process											owl:Class	
GO:1900465	biolink:NamedThing	obsolete negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cellular arginine catabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of arginine catabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of arginine breakdown by negative regulation of transcription from RNA polymerase II promoter|negative regulation of arginine degradation by negative regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T07:38:01Z		True				biological_process											owl:Class	
GO:0032443	biolink:NamedThing	regulation of ergosterol biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.	got7fsn_ti														biological_process											owl:Class	
GO:0042938	biolink:NamedThing	dipeptide transport	The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:1903405	biolink:NamedThing	protein localization to nuclear body	A process in which a protein is transported to, or maintained in, a location within a nuclear body.	got7fsn_ti	protein localization in nuclear body|protein localisation in nuclear body|protein localisation to nuclear body						mah	2014-09-01T13:57:11Z						biological_process											owl:Class	
CHEBI:60579	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009280	biolink:NamedThing	obsolete cell wall inner membrane	OBSOLETE. In Gram-negative bacteria the membrane that separates the cytoplasm from the murein sacculus.	got7fsn_ti	cell wall inner membrane|cytoplasmic membrane				This term was made obsolete because it was defined inaccurately.	GO:0009276				True				cellular_component											owl:Class	
GO:0001560	biolink:NamedThing	regulation of cell growth by extracellular stimulus	Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.	got7fsn_ti	interpretation of external signals that regulate cell growth|regulation of growth by exogenous stimulus|regulation of growth by exogenous stimuli|regulation of growth by external stimuli|regulation of cell growth by sensing of exogenous stimulus|regulation of growth by external stimulus|regulation of cell growth by detection of exogenous stimulus|regulation of growth by exogenous signal|regulation of growth by external signal													biological_process											owl:Class	
GO:1901922	biolink:NamedThing	regulation of sclerotium development	Any process that modulates the frequency, rate or extent of sclerotium development.	got7fsn_ti							di	2013-02-15T20:00:19Z						biological_process											owl:Class	
GO:1905437	biolink:NamedThing	positive regulation of histone H3-K4 trimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K4 trimethylation.	got7fsn_ti	upregulation of histone H3-K4 trimethylation|activation of histone H3-K4 trimethylation|up regulation of histone H3-K4 trimethylation|up-regulation of histone H3-K4 trimethylation						hbye	2016-09-14T13:09:11Z						biological_process											owl:Class	
GO:0001148	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019944	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0062136	biolink:NamedThing	low-density lipoprotein receptor complex	A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors.	got7fsn_ti	LDL receptor complex|LDLR complex|low-density lipoprotein particle receptor complex						dph	2019-07-02T13:41:28Z						cellular_component											owl:Class	
GO:1904956	biolink:NamedThing	regulation of midbrain dopaminergic neuron differentiation	Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.	got7fsn_ti	regulation of mDA neuron differentiation|regulation of DA neurogenesis from midbrain floor plate|regulation of midbrain DA neurogenesis|regulation of midbrain dopaminergic neuron production						bf	2016-02-09T12:00:21Z						biological_process											owl:Class	
GO:0016718	biolink:NamedThing	obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous	OBSOLETE. A grouping term for oxidoreductases, acting on paired donors with incorporation or reduction of molecular oxygen, that cannot be more accurately categorized.	got7fsn_ti	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous				This term was made obsolete because it was an unnecessary grouping term.	GO:0016705				True				molecular_function											owl:Class	
GO:2000068	biolink:NamedThing	regulation of defense response to insect	Any process that modulates the frequency, rate or extent of defense response to insect.	got7fsn_ti	regulation of physiological defense response to insect						tb	2010-08-23T09:30:00Z						biological_process											owl:Class	
GO:0032459	biolink:NamedThing	regulation of protein oligomerization	Any process that modulates the frequency, rate or extent of protein oligomerization.	got7fsn_ti														biological_process											owl:Class	
GO:0016264	biolink:NamedThing	gap junction assembly	Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.	got7fsn_ti														biological_process											owl:Class	
GO:0051769	biolink:NamedThing	regulation of nitric-oxide synthase biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.	got7fsn_ti	regulation of NO synthase biosynthetic process|regulation of nitric-oxide synthase (type II) biosynthesis|regulation of NOS2 synthase biosynthetic process|regulation of NOS2 synthase biosynthesis|regulation of nitric-oxide synthase (type II) biosynthetic process|regulation of NOS biosynthetic process|regulation of nitric-oxide synthase (type 2) biosynthetic process|regulation of nitric-oxide synthase (type 2) biosynthesis|regulation of nitric-oxide synthase 2 biosynthetic process|regulation of NO synthase biosynthesis|regulation of NOS biosynthesis										GO:0051772			biological_process											owl:Class	
GO:1901802	biolink:NamedThing	1,5-anhydro-D-fructose catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose.	got7fsn_ti	1,5-anhydro-D-fructose catabolism|1,5-anhydro-D-fructose degradation|1,5-anhydro-D-fructose breakdown						yaf	2013-01-22T09:56:25Z						biological_process											owl:Class	
GO:0034197	biolink:NamedThing	triglyceride transport	The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.	got7fsn_ti	triacylglycerol transport													biological_process											owl:Class	
GO:0051963	biolink:NamedThing	regulation of synapse assembly	Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.	got7fsn_ti	regulation of synapse biogenesis|regulation of synaptogenesis													biological_process											owl:Class	
GO:1900947	biolink:NamedThing	regulation of isoprene biosynthetic process	Any process that modulates the frequency, rate or extent of isoprene biosynthetic process.	got7fsn_ti	regulation of hemiterpene biosynthetic process|regulation of 2-methyl-1,3-butadiene biosynthetic process|regulation of 2-methyl-1,3-butadiene biosynthesis|regulation of hemiterpene biosynthesis						tt	2012-06-14T03:21:26Z						biological_process											owl:Class	
GO:2001092	biolink:NamedThing	arabinotriose transport	The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T01:59:36Z						biological_process											owl:Class	
GO:0030227	biolink:NamedThing	obsolete apolipoprotein E receptor activity	OBSOLETE. Combining with apolipoprotein E to initiate a change in cell activity.	got7fsn_ti	apolipoprotein E receptor activity|ApoE receptor			GO:0030229	This term was made obsolete because no known receptor binds apolipoprotein E; instead, receptors bind holo-lipoprotein E (apolipoprotein E + bound lipid).					True				molecular_function											owl:Class	
GO:0071440	biolink:NamedThing	regulation of histone H3-K14 acetylation	Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.	got7fsn_ti	regulation of histone H3 acetylation at K14|regulation of histone H3K14 acetylation						mah	2009-12-16T03:24:53Z						biological_process											owl:Class	
GO:2001139	biolink:NamedThing	negative regulation of phospholipid transport	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.	got7fsn_ti							kmv	2011-10-14T06:16:11Z						biological_process											owl:Class	
GO:1901327	biolink:NamedThing	response to tacrolimus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus.	got7fsn_ti	response to tacrolimus hydrate|response to FK506						mah	2012-08-30T10:14:40Z						biological_process											owl:Class	
GO:0045982	biolink:NamedThing	negative regulation of purine nucleobase metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.	got7fsn_ti	negative regulation of purine base metabolic process|negative regulation of purine base metabolism|downregulation of purine base metabolic process|inhibition of purine base metabolic process|down regulation of purine base metabolic process|down-regulation of purine base metabolic process													biological_process											owl:Class	
GO:0032210	biolink:NamedThing	regulation of telomere maintenance via telomerase	Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.	got7fsn_ti														biological_process											owl:Class	
GO:0044137	biolink:NamedThing	obsolete growth of symbiont on or near host rhizosphere	OBSOLETE. The increase in size or mass of symbiont occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18786			This term was obsoleted because it represents both a process and a location.		jl	2009-08-04T04:19:07Z		True				biological_process											owl:Class	
GO:0046829	biolink:NamedThing	negative regulation of RNA import into nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.	got7fsn_ti	inhibition of RNA import into nucleus|down regulation of RNA import into nucleus|negative regulation of RNA import into cell nucleus|negative regulation of RNA transport from cytoplasm to nucleus|downregulation of RNA import into nucleus|negative regulation of RNA-nucleus import|down-regulation of RNA import into nucleus													biological_process											owl:Class	
OBO:OBA_0000103	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0036346	biolink:NamedThing	cellular response to L-cysteine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration.	got7fsn_ti							bf	2012-09-18T14:21:54Z						biological_process											owl:Class	
GO:0000303	biolink:NamedThing	response to superoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.	got7fsn_ti														biological_process											owl:Class	
GO:0001219	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036490	biolink:NamedThing	regulation of translation in response to endoplasmic reticulum stress	Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.	got7fsn_ti	regulation of translation in response to ER stress						bf	2015-02-05T09:50:11Z						biological_process											owl:Class	
GO:0036419	biolink:NamedThing	integral component of mycolate outer membrane	The component of the mycolate outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to mycolate outer membrane|integral to mycomembrane|integral to MOM						bf	2013-09-05T20:20:04Z						cellular_component											owl:Class	
GO:0046963	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate transport	The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	3'-phosphoadenosine 5'-phosphosulphate transport|PAPS transport|adenosine 3'-phosphate 5'-phosphosulfate transport													biological_process											owl:Class	
PO:0009061	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048490	biolink:NamedThing	anterograde synaptic vesicle transport	The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.	got7fsn_ti	anterograde axonal transport of synaptic vesicle													biological_process											owl:Class	
GO:0045415	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016678	biolink:NamedThing	obsolete oxidoreductase activity, acting on heme group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces an acceptor other than a nitrogenous group or oxygen.	got7fsn_ti	oxidoreductase activity, acting on haem group of donors, other acceptors|oxidoreductase activity, acting on heme group of donors, other acceptors				This term was made obsolete because it was an unnecessary grouping term.	GO:0016675				True				molecular_function											owl:Class	
GO:2000876	biolink:NamedThing	positive regulation of glyoxylate cycle	Any process that activates or increases the frequency, rate or extent of glyoxylate cycle.	got7fsn_ti	positive regulation of glyoxylate bypass						bf	2011-07-27T01:27:18Z						biological_process											owl:Class	
GO:1900417	biolink:NamedThing	obsolete negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of transmembrane transport.	got7fsn_ti					The term was obsoleted because it is better represented by a GO-CAM model.		mah	2012-04-20T03:42:55Z		True				biological_process											owl:Class	
GO:0085011	biolink:NamedThing	obsolete interaction with host via protein secreted by Sec complex	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Sec complex. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with host via protein secreted by Sec secretion system				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:18:36Z		True				biological_process											owl:Class	
GO:0070642	biolink:NamedThing	vitamin D5 metabolic process	The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol.	got7fsn_ti	vitamin D5 metabolism						mah	2009-05-08T02:47:41Z						biological_process											owl:Class	
GO:0071289	biolink:NamedThing	cellular response to nickel ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus.	got7fsn_ti	cellular response to nickel						mah	2009-12-10T04:07:31Z						biological_process											owl:Class	
GO:0033320	biolink:NamedThing	UDP-D-xylose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-D-xylose anabolism|UDP-D-xylose biosynthesis|UDP-D-xylose synthesis|UDP-D-xylose formation											MetaCyc:PWY-4821		biological_process											owl:Class	
CHEBI:61119	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006630	biolink:NamedThing	obsolete lipid binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lipid binding				This term was made obsolete because it represents a molecular function and not a biological process.	GO:0008289				True				biological_process											owl:Class	
CHEBI:52288	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046502	biolink:NamedThing	uroporphyrinogen III metabolic process	The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds.	got7fsn_ti	uroporphyrinogen III metabolism													biological_process											owl:Class	
GO:1900190	biolink:NamedThing	regulation of single-species biofilm formation	Any process that modulates the frequency, rate or extent of single-species biofilm formation.	got7fsn_ti							di	2012-03-19T12:42:04Z						biological_process											owl:Class	
GO:0070315	biolink:NamedThing	G1 to G0 transition involved in cell differentiation	A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.	got7fsn_ti	G1/G0 transition involved in cell differentiation													biological_process											owl:Class	
GO:2000290	biolink:NamedThing	regulation of myotome development	Any process that modulates the frequency, rate or extent of myotome development.	got7fsn_ti							mah	2010-12-20T10:22:05Z						biological_process											owl:Class	
GO:1902505	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903224	biolink:NamedThing	regulation of endodermal cell differentiation	Any process that modulates the frequency, rate or extent of endodermal cell differentiation.	got7fsn_ti	regulation of endoderm cell differentiation						als	2014-07-29T13:22:35Z						biological_process											owl:Class	
GO:0042846	biolink:NamedThing	glycol catabolic process	The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.	got7fsn_ti	glycol breakdown|dihydric alcohol catabolic process|dihydric alcohol catabolism|glycol catabolism|glycol degradation													biological_process											owl:Class	
GO:0031229	biolink:NamedThing	intrinsic component of nuclear inner membrane	The component of the nuclear inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to nuclear inner membrane													cellular_component											owl:Class	
GO:2000124	biolink:NamedThing	regulation of endocannabinoid signaling pathway	Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.	got7fsn_ti	regulation of endocannabinoid signalling pathway						mah	2010-09-29T09:05:43Z						biological_process											owl:Class	
GO:0008506	biolink:NamedThing	sucrose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in).	got7fsn_ti	hydrogen/sucrose transporter activity|sucrose:hydrogen symporter activity													molecular_function											owl:Class	
GO:1902858	biolink:NamedThing	propionyl-CoA metabolic process	The chemical reactions and pathways involving propionyl-CoA.	got7fsn_ti	propionyl-CoA metabolism						tt	2014-04-03T03:10:17Z						biological_process											owl:Class	
GO:0006990	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response.	got7fsn_ti	positive regulation of transcription of target genes involved in unfolded protein response|unfolded protein response, target gene transcriptional activation|unfolded protein response, up regulation of target gene transcription|unfolded protein response, upregulation of target gene transcription|unfolded protein response, activation of target gene transcription|unfolded protein response, stimulation of target gene transcription|unfolded protein response, up-regulation of target gene transcription|unfolded protein response, positive regulation of target gene transcription													biological_process											owl:Class	
GO:1901401	biolink:NamedThing	regulation of tetrapyrrole metabolic process	Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.	got7fsn_ti	regulation of tetrapyrrole metabolism						tt	2012-10-01T14:34:03Z						biological_process											owl:Class	
GO:1903081	biolink:NamedThing	negative regulation of C-C chemokine receptor CCR7 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.	got7fsn_ti	downregulation of C-C chemokine receptor CCR7 signalling pathway|down regulation of CCR7 signaling pathway|downregulation of C-C chemokine receptor CCR7 signaling pathway|inhibition of C-C chemokine receptor CCR7 signaling pathway|down-regulation of CCR7 signaling pathway|down regulation of C-C chemokine receptor CCR7 signalling pathway|negative regulation of C-C chemokine receptor CCR7 signalling pathway|downregulation of CCR7 signaling pathway|inhibition of C-C chemokine receptor CCR7 signalling pathway|negative regulation of CCR7 signaling pathway|inhibition of CCR7 signaling pathway|down-regulation of C-C chemokine receptor CCR7 signaling pathway|down-regulation of C-C chemokine receptor CCR7 signalling pathway|down regulation of C-C chemokine receptor CCR7 signaling pathway						rl	2014-05-29T18:32:55Z						biological_process											owl:Class	
GO:1900237	biolink:NamedThing	positive regulation of induction of conjugation with cellular fusion	Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion.	got7fsn_ti	up-regulation of induction of conjugation with cellular fusion|up regulation of induction of conjugation with cellular fusion|upregulation of induction of conjugation with cellular fusion						al	2012-03-26T10:14:16Z						biological_process											owl:Class	
GO:0048713	biolink:NamedThing	regulation of oligodendrocyte differentiation	Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:1904642	biolink:NamedThing	cellular response to dinitrophenol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.	got7fsn_ti	cellular response to dinitrophenols						sl	2015-08-31T20:13:18Z						biological_process											owl:Class	
GO:1904586	biolink:NamedThing	cellular response to putrescine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.	got7fsn_ti	cellular response to 1,4-Diaminobutane|cellular response to tetramethylenediamine|cellular response to 1,4-Butanediamine						sl	2015-08-20T14:35:45Z						biological_process											owl:Class	
GO:1900003	biolink:NamedThing	regulation of serine-type endopeptidase activity	Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity.	got7fsn_ti	regulation of blood coagulation factor activity						kmv	2012-01-09T10:03:15Z						biological_process											owl:Class	
GO:0071802	biolink:NamedThing	negative regulation of podosome assembly	Any process that stops, prevents or reduces the rate or extent of podosome assembly.	got7fsn_ti	downregulation of podosome assembly|down-regulation of podosome assembly|inhibition of podosome assembly|down regulation of podosome assembly						mah	2010-09-03T01:49:14Z						biological_process											owl:Class	
GO:1990458	biolink:NamedThing	lipooligosaccharide binding	Binding to lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria.	got7fsn_ti	endotoxin binding|LOS binding				ChEBI distinguishes an oligosaccharide from a polysaccharide as the latter being anything of length 10 or greater.		hjd	2014-08-15T19:58:08Z						molecular_function											owl:Class	
GO:0034308	biolink:NamedThing	primary alcohol metabolic process	The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.	got7fsn_ti	primary alcohol metabolism|monohydric alcohol metabolic process													biological_process											owl:Class	
GO:0043132	biolink:NamedThing	NAD transport	The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.	got7fsn_ti	nicotinamide adenine dinucleotide transport|NADH transport|NAD (reduced) transport|reduced nicotinamide adenine dinucleotide transport|reduced NAD transport|NAD (oxidized) transport|oxidized nicotinamide adenine dinucleotide transport|oxidized NAD transport													biological_process											owl:Class	
GO:0001036	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005050	biolink:NamedThing	obsolete peroxisome receptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peroxisome receptor				This term was made obsolete because it describes a cellular component.	GO:0005777|GO:0038023				True				molecular_function											owl:Class	
GO:1902387	biolink:NamedThing	ceramide 1-phosphate binding	Binding to ceramide 1-phosphate.	got7fsn_ti							uh	2013-09-05T05:51:08Z						molecular_function											owl:Class	
CHEBI:26020	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044130	biolink:NamedThing	obsolete negative regulation of growth of symbiont in host	OBSOLETE. Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T02:42:25Z		True				biological_process											owl:Class	
GO:0033955	biolink:NamedThing	obsolete mitochondrial DNA inheritance	OBSOLETE. The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission.	got7fsn_ti	mitochondrial DNA segregation|mitochondrial chromosome segregation	https://github.com/geneontology/go-ontology/issues/18417			This term was obsoleted because it represented a phenotype.	GO:0000002|GO:0000266				True	GO:0090142			biological_process											owl:Class	
GO:0006659	biolink:NamedThing	phosphatidylserine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.	got7fsn_ti	phosphatidylserine synthesis|phosphatidylserine formation|phosphatidylserine biosynthesis|phosphatidylserine anabolism													biological_process											owl:Class	
GO:1903222	biolink:NamedThing	quinolinic acid transmembrane transport	The process in which quinolinic acid is transported across a membrane.	got7fsn_ti							di	2014-07-26T07:29:07Z						biological_process											owl:Class	
CHEBI:65932	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019211	biolink:NamedThing	phosphatase activator activity	Binds to and increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.	got7fsn_ti														molecular_function											owl:Class	
GO:1903909	biolink:NamedThing	regulation of receptor clustering	Any process that modulates the frequency, rate or extent of receptor clustering.	got7fsn_ti							als	2015-02-09T10:56:33Z						biological_process											owl:Class	
GO:0052216	biolink:NamedThing	obsolete chemotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	chemotaxis in response to environment of other organism|chemotaxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
UBERON:0001009	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58315	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042291	biolink:NamedThing	obsolete Hub1 hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	Hub1 hydrolase activity				This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True				molecular_function											owl:Class	
GO:0009170	biolink:NamedThing	purine deoxyribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:1904444	biolink:NamedThing	regulation of establishment of Sertoli cell barrier	Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier.	got7fsn_ti	regulation of establishment of blood-testis barrier|regulation of establishment of BTB|regulation of establishment of SCB						sl	2015-07-06T16:00:41Z						biological_process											owl:Class	
GO:0140434	biolink:NamedThing	positive regulation of protein localization to meiotic spindle pole body	Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body.	got7fsn_ti							pg	2020-02-24T13:27:01Z						biological_process											owl:Class	
GO:0062088	biolink:NamedThing	negative regulation of vein smooth muscle contraction	Any process that decreases the frequency, rate or extent of vein smooth muscle contraction.	got7fsn_ti							dph	2018-11-02T15:28:32Z						biological_process											owl:Class	
GO:1904789	biolink:NamedThing	regulation of mitotic actomyosin contractile ring maintenance	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring maintenance.	got7fsn_ti	regulation of cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle|regulation of contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle						mah	2015-11-06T15:42:49Z						biological_process											owl:Class	
GO:1902666	biolink:NamedThing	obsolete protein localization to Mmi1 nuclear focus complex	OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a Mmi1 nuclear focus complex.	got7fsn_ti	protein localisation in Mmi1 nuclear focus complex|protein localisation to Mmi1 nuclear focus complex|protein localization in Mmi1 nuclear focus complex	https://github.com/geneontology/go-ontology/issues/19063			This term was obsoleted because there is no evidence that this process exists (no factor mediates the localization of proteins to Mmi1 nuclear foci)		mah	2014-01-30T10:42:17Z		True				biological_process											owl:Class	
GO:0010858	biolink:NamedThing	calcium-dependent protein kinase regulator activity	Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner.	got7fsn_ti														molecular_function											owl:Class	
GO:0071863	biolink:NamedThing	regulation of cell proliferation in bone marrow	A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow.	got7fsn_ti	regulation of bone marrow cell proliferation						mah	2010-09-13T02:11:08Z						biological_process											owl:Class	
GO:1903604	biolink:NamedThing	cytochrome metabolic process	The chemical reactions and pathways involving a cytochrome.	got7fsn_ti	cytochrome metabolism						dph	2014-11-13T20:01:09Z						biological_process											owl:Class	
GO:1900360	biolink:NamedThing	regulation of pentasaccharide transport	Any process that modulates the frequency, rate or extent of pentasaccharide transport.	got7fsn_ti							tt	2012-04-06T02:19:27Z						biological_process											owl:Class	
GO:2000162	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.	got7fsn_ti							dph	2010-10-05T01:05:24Z						biological_process											owl:Class	
GO:0052573	biolink:NamedThing	UDP-D-galactose metabolic process	The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	UDP-D-galactopyranose metabolic process|UDP-D-galactose metabolism|uridine diphosphate galactose metabolic process|uridine diphosphate galactose metabolism|UDP-galactose metabolic process|UDP-galactose metabolism|UDP-D-galactopyranose metabolism							2010-07-23T03:29:57Z						biological_process											owl:Class	
GO:0032049	biolink:NamedThing	cardiolipin biosynthetic process	The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.	got7fsn_ti	diphosphatidylglycerol biosynthesis|diphosphatidylglycerol biosynthetic process											MetaCyc:PWY-5269		biological_process											owl:Class	
GO:0043693	biolink:NamedThing	monoterpene biosynthetic process	The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure.	got7fsn_ti	monoterpene biosynthesis													biological_process											owl:Class	
GO:0097031	biolink:NamedThing	obsolete mitochondrial respiratory chain complex I biogenesis	OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15173			The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		pr	2011-04-05T02:53:14Z		True				biological_process											owl:Class	
GO:0010660	biolink:NamedThing	regulation of muscle cell apoptotic process	Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.	got7fsn_ti	regulation of muscle cell apoptosis													biological_process											owl:Class	
GO:0072430	biolink:NamedThing	obsolete detection of DNA damage stimulus involved in mitotic G1 DNA damage checkpoint	OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition DNA damage checkpoint.	got7fsn_ti	detection of DNA damage stimulus involved in mitotic cell cycle G1/S transition DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint sensor process|sensing involved in mitotic cell cycle G1/S transition DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:37:40Z		True				biological_process											owl:Class	
GO:0018326	biolink:NamedThing	obsolete enzyme active site formation via S-acetyl-L-cysteine	OBSOLETE. The transient acetylation of peptidyl-cysteine to form S-acetyl-L-cysteine.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:1310545.					True		RESID:AA0056		biological_process											owl:Class	
GO:0033628	biolink:NamedThing	regulation of cell adhesion mediated by integrin	Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.	got7fsn_ti	regulation of cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0045707	biolink:NamedThing	regulation of adult salivary gland boundary specification	Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism.	got7fsn_ti	regulation of adult salivary gland determination													biological_process											owl:Class	
GO:0009114	biolink:NamedThing	hypoxanthine catabolic process	The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.	got7fsn_ti	hypoxanthine oxidation|hypoxanthine breakdown|hypoxanthine degradation|hypoxanthine catabolism										GO:0006150			biological_process											owl:Class	
GO:0043444	biolink:NamedThing	acetone catabolic process	The chemical reactions and pathways resulting in the breakdown of acetone, propan-2-one.	got7fsn_ti	dimethyl ketone catabolic process|acetone degradation|acetone catabolism|2-propanone catabolism|acetone breakdown|2-propanone catabolic process|dimethyl ketone catabolism|propan-2-one catabolic process|propan-2-one catabolism													biological_process											owl:Class	
GO:1900240	biolink:NamedThing	negative regulation of phenotypic switching	Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching.	got7fsn_ti	downregulation of phenotypic switching|downregulation of phenotypic dimorphism|inhibition of phenotypic dimorphism|negative regulation of phenotypic dimorphism|down regulation of phenotypic dimorphism|down-regulation of phenotypic dimorphism|down-regulation of phenotypic switching|down regulation of phenotypic switching|inhibition of phenotypic switching						di	2012-03-28T01:49:26Z						biological_process											owl:Class	
GO:0060624	biolink:NamedThing	regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process	Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.	got7fsn_ti	regulation of ascospore wall 1,3-beta-glucan biosynthetic process|regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process						dph	2009-05-18T02:18:10Z						biological_process											owl:Class	
GO:0001797	biolink:NamedThing	negative regulation of type IIa hypersensitivity	Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response.	got7fsn_ti	downregulation of type IIa hypersensitivity|down regulation of type IIa hypersensitivity|down-regulation of type IIa hypersensitivity|inhibition of type IIa hypersensitivity													biological_process											owl:Class	
GO:1903811	biolink:NamedThing	L-asparagine import across plasma membrane	The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	asparagine import|L-asparagine import into cell						tb	2012-09-24T14:28:58Z			GO:0090469			biological_process											owl:Class	
GO:1904711	biolink:NamedThing	regulation of Wnt-Frizzled-LRP5/6 complex assembly	Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.	got7fsn_ti	regulation of WNT-FZD-LRP6 complex formation|regulation of WNT-FZD-LRP6 complex assembly|regulation of Frizzled-LRP5/6 complex formation|regulation of Wnt-induced Frizzled-LRP5/6 complex formation|regulation of Frizzled-LRP5/6 complex assembly|regulation of Wnt receptor complex assembly|regulation of Wnt-FZD-LRP5/6 trimeric complex formation|regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|regulation of WNT-FZD-LRP5 complex assembly|regulation of WNT-FZD-LRP5 complex formation|regulation of Wnt-FZD-LRP5/6 trimeric complex assembly						bf	2015-10-05T14:02:22Z						biological_process											owl:Class	
GO:0061187	biolink:NamedThing	regulation of ribosomal DNA heterochromatin assembly	Any process that modulates the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin.	got7fsn_ti	regulation of chromatin silencing at rDNA	https://github.com/geneontology/go-ontology/issues/19238					dph	2010-07-14T09:04:16Z						biological_process											owl:Class	
GO:0044592	biolink:NamedThing	response to pullulan	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus.	got7fsn_ti							jl	2012-04-26T03:59:06Z						biological_process											owl:Class	
GO:1902296	biolink:NamedThing	DNA strand elongation involved in cell cycle DNA replication	Any DNA strand elongation that is involved in cell cycle DNA replication.	got7fsn_ti	DNA strand elongation during DNA replication involved in cell cycle DNA replication|DNA replication elongation involved in cell cycle DNA replication						jl	2013-07-10T11:47:02Z						biological_process											owl:Class	
GO:0090505	biolink:NamedThing	epiboly involved in wound healing	The expansion of one cell sheet over other cells involved in wound healing.	got7fsn_ti							tb	2012-10-22T12:38:51Z						biological_process											owl:Class	
GO:1905002	biolink:NamedThing	positive regulation of membrane repolarization during atrial cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.	got7fsn_ti	up regulation of membrane repolarization during atrial cardiac muscle cell action potential|up-regulation of membrane repolarization during atrial cardiac muscle cell action potential|positive regulation of atrial repolarization|activation of atrial repolarization|positive regulation of electrocardiogram QRS complex|activation of electrocardiogram QRS complex|up regulation of electrocardiogram QRS complex|up-regulation of electrocardiogram QRS complex|up-regulation of atrial repolarization|activation of membrane repolarization during atrial cardiac muscle cell action potential|upregulation of membrane repolarization during atrial cardiac muscle cell action potential|upregulation of atrial repolarization|upregulation of electrocardiogram QRS complex|up regulation of atrial repolarization						rph	2016-03-01T13:28:21Z						biological_process											owl:Class	
GO:0052215	biolink:NamedThing	obsolete energy taxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in the environment of a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	energy taxis in environment of other organism during symbiotic interaction|energy taxis in response to environment of other organism				This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0051419	biolink:NamedThing	obsolete nebulin binding	OBSOLETE. Binding to nebulin, a large protein (approximately 800kD) that is anchored at the Z-disc by its C-terminal region and spans the length of the thin filament, ending at the edge of the H-zone.	got7fsn_ti	nebulin binding			GO:0008092	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:1901497	biolink:NamedThing	response to diphenyl ether	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus.	got7fsn_ti							tt	2012-10-16T14:58:08Z						biological_process											owl:Class	
GO:0007581	biolink:NamedThing	obsolete age-dependent yeast cell size increase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	age-dependent yeast cell size increase				This term was made obsolete because it does not describe a biological process.	GO:0007571				True				biological_process											owl:Class	
GO:0010757	biolink:NamedThing	negative regulation of plasminogen activation	Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.	got7fsn_ti	inhibition of plasminogen activation													biological_process											owl:Class	
GO:0010791	biolink:NamedThing	DNA double-strand break processing involved in repair via synthesis-dependent strand annealing	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing.	got7fsn_ti														biological_process											owl:Class	
GO:2000298	biolink:NamedThing	regulation of Rho-dependent protein serine/threonine kinase activity	Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.	got7fsn_ti	regulation of Rho-associated protein kinase activity|regulation of ROCK kinase activity						mah	2010-12-23T11:44:50Z						biological_process											owl:Class	
GO:0018704	biolink:NamedThing	obsolete 5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity	OBSOLETE. Catalysis of the reaction: 5-chloro-2-hydroxymuconic semialdehyde + H+ + 2 e- = Cl- + 2-hydroxymuconic semialdehyde.	got7fsn_ti	5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity				This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.					True				molecular_function											owl:Class	
GO:1904987	biolink:NamedThing	regulation of endothelial cell activation	Any process that modulates the frequency, rate or extent of endothelial cell activation.	got7fsn_ti							bc	2016-02-29T16:16:09Z						biological_process											owl:Class	
GO:0006275	biolink:NamedThing	regulation of DNA replication	Any process that modulates the frequency, rate or extent of DNA replication.	got7fsn_ti														biological_process											owl:Class	
GO:0071445	biolink:NamedThing	obsolete cellular response to protein stimulus	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus.	got7fsn_ti	cellular response to protein stimulus				This term was made obsolete because more specific terms exist.	GO:0071363|GO:0071218|GO:0034620|GO:0032870|GO:0071345	mah	2009-12-16T04:12:04Z		True				biological_process											owl:Class	
CHEBI:18310	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902020	biolink:NamedThing	negative regulation of cilium-dependent cell motility	Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.	got7fsn_ti	inhibition of ciliary cell motility|negative regulation of cilium cell motility|down regulation of ciliary cell motility|negative regulation of ciliary cell motility|downregulation of ciliary cell motility|down-regulation of ciliary cell motility						jl	2013-03-27T14:42:42Z						biological_process											owl:Class	
GO:0075176	biolink:NamedThing	obsolete negative regulation of cAMP-mediated signaling in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of symbiont cAMP-mediated signal transduction in response to host|negative regulation of cAMP-mediated signal transduction in response to host|negative regulation of cAMP-mediated signalling in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0019594	biolink:NamedThing	mannitol metabolic process	The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.	got7fsn_ti	mannitol metabolism													biological_process											owl:Class	
GO:0042606	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002663	biolink:NamedThing	positive regulation of B cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction.	got7fsn_ti	positive regulation of B-cell tolerance induction|upregulation of B cell tolerance induction|positive regulation of B-lymphocyte tolerance induction|activation of B cell tolerance induction|up-regulation of B cell tolerance induction|stimulation of B cell tolerance induction|up regulation of B cell tolerance induction|positive regulation of B lymphocyte tolerance induction													biological_process											owl:Class	
GO:0033305	biolink:NamedThing	chlorophyll a biosynthetic process	The chemical reactions and pathways leading to the formation of chlorophyll a.	got7fsn_ti	chlorophyll a biosynthesis|chlorophyll a anabolism|chlorophyll a synthesis|chlorophyll a formation													biological_process											owl:Class	
GO:0072329	biolink:NamedThing	monocarboxylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.	got7fsn_ti							mah	2010-11-02T04:41:55Z						biological_process											owl:Class	
GO:0010126	biolink:NamedThing	mycothiol metabolic process	The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.	got7fsn_ti	mycothiol metabolism													biological_process											owl:Class	
UBERON:0002538	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000169	biolink:NamedThing	regulation of peptidyl-cysteine S-nitrosylation	Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.	got7fsn_ti							rl	2010-10-07T10:49:32Z						biological_process											owl:Class	
GO:2001291	biolink:NamedThing	codeine metabolic process	The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.	got7fsn_ti	codeine metabolism						pr	2012-02-14T01:10:03Z						biological_process											owl:Class	
GO:0002605	biolink:NamedThing	negative regulation of dendritic cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.	got7fsn_ti	down-regulation of dendritic cell antigen processing and presentation|inhibition of dendritic cell antigen processing and presentation|downregulation of dendritic cell antigen processing and presentation|down regulation of dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0018944	biolink:NamedThing	tri-n-butyltin metabolic process	The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms.	got7fsn_ti	tri-n-butyltin metabolism											UM-BBD_pathwayID:tbt		biological_process											owl:Class	
GO:0018961	biolink:NamedThing	pentachlorophenol metabolic process	The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.	got7fsn_ti	PCP metabolic process|pentachlorophenol metabolism|PCP metabolism											UM-BBD_pathwayID:pcp		biological_process											owl:Class	
UBERON:0002256	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042343	biolink:NamedThing	indole glucosinolate metabolic process	The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.	got7fsn_ti	indole glucosinolate metabolism													biological_process											owl:Class	
GO:0006047	biolink:NamedThing	UDP-N-acetylglucosamine metabolic process	The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-N-acetylglucosamine metabolism													biological_process											owl:Class	
GO:0032224	biolink:NamedThing	positive regulation of synaptic transmission, cholinergic	Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.	got7fsn_ti	activation of synaptic transmission, cholinergic|up regulation of synaptic transmission, cholinergic|up-regulation of synaptic transmission, cholinergic|upregulation of synaptic transmission, cholinergic|stimulation of synaptic transmission, cholinergic													biological_process											owl:Class	
GO:1901932	biolink:NamedThing	bicyclogermacrene metabolic process	The chemical reactions and pathways involving bicyclogermacrene.	got7fsn_ti	bicyclogermacrene metabolism						ms	2013-02-18T14:54:52Z						biological_process											owl:Class	
GO:1903671	biolink:NamedThing	negative regulation of sprouting angiogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.	got7fsn_ti	inhibition of sprouting angiogenesis|down regulation of sprouting angiogenesis|downregulation of sprouting angiogenesis|down-regulation of sprouting angiogenesis						pga	2014-11-27T10:10:59Z						biological_process											owl:Class	
GO:0051164	biolink:NamedThing	L-xylitol metabolic process	The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets.	got7fsn_ti	L-xylitol metabolism													biological_process											owl:Class	
GO:2000138	biolink:NamedThing	positive regulation of cell proliferation involved in heart morphogenesis	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.	got7fsn_ti							dph	2010-09-29T12:43:57Z						biological_process											owl:Class	
GO:0008658	biolink:NamedThing	penicillin binding	Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:64602	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033394	biolink:NamedThing	beta-alanine biosynthetic process via 1,3 diaminopropane	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.	got7fsn_ti	beta-alanine synthesis via 1,3 diaminopropane|beta-alanine biosynthesis via 1,3 diaminopropane|beta-alanine formation via 1,3 diaminopropane|beta-alanine anabolism via 1,3 diaminopropane											MetaCyc:PWY-3981		biological_process											owl:Class	
GO:0033386	biolink:NamedThing	geranylgeranyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.	got7fsn_ti	geranylgeranyl diphosphate biosynthesis|geranylgeranyl diphosphate synthesis|geranylgeranyl diphosphate anabolism|geranylgeranyl diphosphate formation											MetaCyc:PWY-5120|MetaCyc:PWY-5121		biological_process											owl:Class	
GO:0031068	biolink:NamedThing	positive regulation of histone deacetylation at centromere	Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA.	got7fsn_ti	stimulation of histone deacetylation at centromere|up-regulation of histone deacetylation at centromere|upregulation of histone deacetylation at centromere|up regulation of histone deacetylation at centromere|activation of histone deacetylation at centromere													biological_process											owl:Class	
GO:2001091	biolink:NamedThing	nigerotriose transport	The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T01:51:49Z						biological_process											owl:Class	
GO:0052218	biolink:NamedThing	obsolete positive energy taxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive energy taxis in response to environment of other organism|positive energy taxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
UBERON:0002073	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903478	biolink:NamedThing	actin filament bundle convergence involved in mitotic contractile ring assembly	Any actin filament bundle convergence that is involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti	actin filament bundle convergence involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis|actin filament bundle convergence involved in mitotic actomyosin contractile ring assembly|actin filament bundle convergence involved in contractile ring assembly involved in mitotic cytokinesis|actin filament bundle convergence involved in cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis						vw	2014-09-23T15:03:11Z						biological_process											owl:Class	
GO:1901886	biolink:NamedThing	2-hydroxybenzoyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA.	got7fsn_ti	2-hydroxybenzoyl-CoA degradation|2-hydroxybenzoyl-CoA catabolism|2-hydroxybenzoyl-CoA breakdown						ms	2013-02-06T14:06:08Z						biological_process											owl:Class	
GO:0009158	biolink:NamedThing	ribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	ribonucleoside monophosphate breakdown|ribonucleoside monophosphate catabolism|ribonucleoside monophosphate degradation													biological_process											owl:Class	
CHEBI:33857	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22307	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009935	biolink:NamedThing	obsolete nutrient import	OBSOLETE. The directed movement of nutrients into a cell or organelle.	got7fsn_ti	nutrient uptake|nutrient import				This term was made obsolete because "nutrient" is not defined, and does not have a consistent meaning.	GO:0006810				True				biological_process											owl:Class	
GO:0010730	biolink:NamedThing	negative regulation of hydrogen peroxide biosynthetic process	Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	got7fsn_ti	negative regulation of hydrogen peroxide biosynthesis													biological_process											owl:Class	
GO:2000753	biolink:NamedThing	positive regulation of glucosylceramide catabolic process	Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process.	got7fsn_ti	positive regulation of glucosylceramide breakdown|positive regulation of glucosylceramide catabolism|positive regulation of glucosylceramide degradation						rl	2011-06-16T03:12:09Z						biological_process											owl:Class	
GO:1904461	biolink:NamedThing	ergosteryl 3-beta-D-glucoside metabolic process	The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside.	got7fsn_ti	ergosteryl 3-beta-D-glucoside metabolism						mcc	2015-07-09T19:36:19Z						biological_process											owl:Class	
GO:0001606	biolink:NamedThing	obsolete GPR37/endothelin B-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	GPR37/endothelin B-like receptor activity				This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True				molecular_function											owl:Class	
GO:0120061	biolink:NamedThing	negative regulation of gastric emptying	Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.	got7fsn_ti							krc	2017-06-13T21:54:49Z						biological_process											owl:Class	
GO:0009466	biolink:NamedThing	obsolete class I cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	class I cytochrome c				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
UBERON:0005093	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051925	biolink:NamedThing	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity	OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel.	got7fsn_ti	regulation of calcium transport via voltage-gated calcium channel|regulation of calcium ion transport via voltage-gated calcium channel activity				This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0005245				True				biological_process											owl:Class	
GO:0016569	biolink:NamedThing	obsolete covalent chromatin modification	OBSOLETE. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.	got7fsn_ti	chromatin modification	https://github.com/geneontology/go-ontology/issues/22062			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0043521	biolink:NamedThing	regulation of myosin II filament disassembly	Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0007048	biolink:NamedThing	obsolete oncogenesis	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	oncogenesis				This term was made obsolete because it represents a pathological process.					True				biological_process											owl:Class	
GO:0010681	biolink:NamedThing	obsolete cinnamic acid biosynthetic process involved in stilbene metabolism	OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.					True				biological_process											owl:Class	
GO:2000606	biolink:NamedThing	regulation of cell proliferation involved in mesonephros development	Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development.	got7fsn_ti							yaf	2011-04-18T08:42:19Z						biological_process											owl:Class	
GO:0046180	biolink:NamedThing	ketogluconate biosynthetic process	The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.	got7fsn_ti	ketogluconate synthesis|ketogluconate anabolism|ketogluconate biosynthesis|ketogluconate formation													biological_process											owl:Class	
GO:1902199	biolink:NamedThing	3-methylbut-2-enoyl-CoA(4-) catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-).	got7fsn_ti	3-methylbut-2-enoyl-CoA(4-) degradation|3-methylbut-2-enoyl-CoA(4-) catabolism|3-methylbut-2-enoyl-CoA(4-) breakdown						ms	2013-06-06T09:56:16Z						biological_process											owl:Class	
GO:2000866	biolink:NamedThing	positive regulation of estradiol secretion	Any process that activates or increases the frequency, rate or extent of estradiol secretion.	got7fsn_ti	positive regulation of oestradiol secretion						bf	2011-07-26T08:49:20Z						biological_process											owl:Class	
GO:1900234	biolink:NamedThing	regulation of Kit signaling pathway	Any process that modulates the frequency, rate or extent of Kit signaling pathway.	got7fsn_ti	regulation of Kit signalling pathway|regulation of stem cell factor receptor signaling pathway|regulation of stem cell factor signaling pathway						bf	2012-03-23T02:54:13Z						biological_process											owl:Class	
GO:1905147	biolink:NamedThing	regulation of smooth muscle hypertrophy	Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy.	got7fsn_ti							bc	2016-04-15T12:47:07Z						biological_process											owl:Class	
GO:1902579	biolink:NamedThing	multi-organism localization	A localization which involves another organism.	got7fsn_ti	multi organism localization						jl	2013-12-18T13:51:13Z						biological_process											owl:Class	
GO:0010763	biolink:NamedThing	positive regulation of fibroblast migration	Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.	got7fsn_ti	positive regulation of fibroblast cell migration													biological_process											owl:Class	
GO:0048662	biolink:NamedThing	negative regulation of smooth muscle cell proliferation	Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.	got7fsn_ti	down-regulation of smooth muscle cell proliferation|down regulation of smooth muscle cell proliferation|inhibition of smooth muscle cell proliferation|downregulation of smooth muscle cell proliferation|negative regulation of SMC proliferation													biological_process											owl:Class	
CHEBI:58097	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:49603	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003340	biolink:NamedThing	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.	got7fsn_ti							dph	2009-11-24T09:46:12Z						biological_process											owl:Class	
GO:0044667	biolink:NamedThing	(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out).	got7fsn_ti	L-carnitine:4-(trimethylammonio)butanoate antiporter activity|L-carnitine:gamma-butyrobetaine antiporter activity|(R)-carnitine:gamma-butyrobetaine antiporter activity						jl	2012-08-08T11:17:12Z				RHEA:29427		molecular_function											owl:Class	
GO:0015257	biolink:NamedThing	obsolete organic anion channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	organic anion channel activity				This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True				molecular_function											owl:Class	
GO:2000389	biolink:NamedThing	regulation of neutrophil extravasation	Any process that modulates the frequency, rate or extent of neutrophil extravasation.	got7fsn_ti							mah	2011-02-22T11:07:58Z						biological_process											owl:Class	
CHEBI:7872	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044040	biolink:NamedThing	obsolete multi-organism carbohydrate metabolic process	OBSOLETE. The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, that involve more than one organism.	got7fsn_ti	multi-organism carbohydrate metabolism|main pathways of carbohydrate metabolic process|main pathways of carbohydrate metabolism				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0031630	biolink:NamedThing	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.	got7fsn_ti	regulation of synaptic vesicle fusion to presynaptic membrane|regulation of synaptic vesicle fusion to pre-synaptic membrane													biological_process											owl:Class	
GO:2000495	biolink:NamedThing	regulation of cell proliferation involved in compound eye morphogenesis	Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.	got7fsn_ti							bf	2011-03-18T02:18:34Z						biological_process											owl:Class	
GO:0090172	biolink:NamedThing	microtubule cytoskeleton organization involved in homologous chromosome segregation	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis.	got7fsn_ti	microtubule cytoskeleton organisation involved in homologous chromosome segregation|microtubule organization involved in chromosome pairing						tb	2009-12-11T11:07:42Z						biological_process											owl:Class	
GO:0043031	biolink:NamedThing	negative regulation of macrophage activation	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.	got7fsn_ti	negative regulation of macrophage polarization|down regulation of macrophage activation|down-regulation of macrophage activation|downregulation of macrophage activation|inhibition of macrophage activation													biological_process											owl:Class	
GO:0052552	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035864	biolink:NamedThing	response to potassium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.	got7fsn_ti	response to potassium|response to K+ ion						bf	2011-05-25T02:58:45Z						biological_process											owl:Class	
GO:1904182	biolink:NamedThing	regulation of pyruvate dehydrogenase activity	Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity.	got7fsn_ti	regulation of pyruvic dehydrogenase activity|regulation of pyruvic acid dehydrogenase activity						dph	2015-05-05T14:17:27Z						biological_process											owl:Class	
GO:0110023	biolink:NamedThing	negative regulation of cardiac muscle myoblast proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation.	got7fsn_ti							kmv	2017-06-29T15:18:30Z						biological_process											owl:Class	
GO:0052287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0100016	biolink:NamedThing	obsolete regulation of thiamine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates thiamine biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0045942	biolink:NamedThing	negative regulation of phosphorus utilization	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization.	got7fsn_ti	inhibition of phosphorus utilization|downregulation of phosphorus utilization|down-regulation of phosphorus utilization|down regulation of phosphorus utilization													biological_process											owl:Class	
GO:0009934	biolink:NamedThing	regulation of meristem structural organization	Any process that modulates the frequency, rate or extent of meristem organization.	got7fsn_ti	regulation of meristem organisation|regulation of meristem organization													biological_process											owl:Class	
CHEBI:24458	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000547	biolink:NamedThing	regulation of dendritic cell dendrite assembly	Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.	got7fsn_ti	regulation of dendritic extension						ebc	2011-04-03T07:21:55Z						biological_process											owl:Class	
GO:0060097	biolink:NamedThing	cytoskeletal rearrangement involved in phagocytosis, engulfment	The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0004187	biolink:NamedThing	obsolete carboxypeptidase D activity	OBSOLETE. Catalysis of the preferential release of a C-terminal arginine or lysine residue. Function is inhibited by diisopropyl fluorophosphate and sensitive to thiol-blocking reagents.	got7fsn_ti	carboxypeptidase D activity|KEX1DELTAp|saccharomyces cerevisiae KEX1 gene product|carboxypeptidase KEX1 activity|KEX1 carboxypeptidase activity|KEX1 proteinase activity|carboxypeptidase Kex1|carboxypeptidase S1 activity|cereal serine carboxypeptidase II|gene KEX1 serine carboxypeptidase|CPDW-II			GO:0004185	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0043557	biolink:NamedThing	regulation of translation in response to osmotic stress	Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:1905574	biolink:NamedThing	ganglioside GM2 binding	Binding to ganglioside GM2.	got7fsn_ti							pga	2016-10-19T11:17:01Z						molecular_function											owl:Class	
FAO:0000047	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901796	biolink:NamedThing	regulation of signal transduction by p53 class mediator	Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.	got7fsn_ti							hjd	2013-01-18T21:51:39Z						biological_process											owl:Class	
GO:0023039	biolink:NamedThing	obsolete signal initiation by physical damage	OBSOLETE. The process in which a physical damage signal causes activation of a receptor.	got7fsn_ti	signal initiation by physical damage				This term was made obsolete because the meaning of the term is ambiguous.	GO:0038023|GO:0033554		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:2000306	biolink:NamedThing	positive regulation of photomorphogenesis	Any process that activates or increases the frequency, rate or extent of photomorphogenesis.	got7fsn_ti	positive regulation of plant development in response to light						dhl	2011-01-12T07:09:02Z						biological_process											owl:Class	
PR:000001122	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008906	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:145544	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097724	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000931	biolink:NamedThing	negative regulation of cellobiose metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process.	got7fsn_ti	negative regulation of cellobiose metabolism						tt	2011-08-01T12:42:57Z						biological_process											owl:Class	
GO:1900349	biolink:NamedThing	negative regulation of methane biosynthetic process from methylamine	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine.	got7fsn_ti	down regulation of methane biosynthetic process from methylamine|inhibition of methane biosynthetic process from methylamine|down-regulation of methane biosynthetic process from methylamine|downregulation of methane biosynthetic process from methylamine						tt	2012-04-06T02:12:04Z						biological_process											owl:Class	
GO:0003793	biolink:NamedThing	obsolete defense/immunity protein activity	OBSOLETE. Any activity that plays a role in the defense/immune response of an organism against infection and disease.	got7fsn_ti	defense/immunity protein activity|defence/immunity protein activity				This term was made obsolete because it refers to involvement in a biological process.	GO:0006952				True				molecular_function											owl:Class	
GO:0016107	biolink:NamedThing	sesquiterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.	got7fsn_ti	sesquiterpenoid breakdown|sesquiterpenoid degradation|sesquiterpenoid catabolism													biological_process											owl:Class	
GO:0018998	biolink:NamedThing	obsolete metaxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	metaxin				This term was made obsolete because it represents a single gene product and not a complex.	GO:0005741				True				cellular_component											owl:Class	
GO:1905572	biolink:NamedThing	ganglioside GM1 transport to membrane	The directed movement of ganglioside GM1 to membrane.	got7fsn_ti							pga	2016-10-19T10:50:44Z						biological_process											owl:Class	
GO:0032373	biolink:NamedThing	positive regulation of sterol transport	Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	up regulation of sterol transport|stimulation of sterol transport|activation of sterol transport|upregulation of sterol transport|up-regulation of sterol transport													biological_process											owl:Class	
GO:1905102	biolink:NamedThing	positive regulation of apoptosome assembly	Any process that activates or increases the frequency, rate or extent of apoptosome assembly.	got7fsn_ti	up regulation of apoptosome assembly|up-regulation of apoptosome assembly|upregulation of apoptosome formation|activation of apoptosome assembly|up-regulation of apoptosome formation|positive regulation of apoptosome formation|activation of apoptosome formation|up regulation of apoptosome formation|upregulation of apoptosome assembly						bc	2016-04-04T08:57:59Z						biological_process											owl:Class	
GO:0030862	biolink:NamedThing	positive regulation of polarized epithelial cell differentiation	Any process that activates or increases the rate or extent of polarized epithelial cell differentiation.	got7fsn_ti	stimulation of polarized epithelial cell differentiation|upregulation of polarized epithelial cell differentiation|up-regulation of polarized epithelial cell differentiation|activation of polarized epithelial cell differentiation|up regulation of polarized epithelial cell differentiation													biological_process											owl:Class	
GO:0061292	biolink:NamedThing	canonical Wnt signaling pathway involved in mesonephros development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in mesonephros development|canonical Wnt-activated signaling pathway involved in mesonephros development|canonical Wnt receptor signaling pathway involved in mesonephros development						dph	2010-09-03T12:23:09Z						biological_process											owl:Class	
GO:2000416	biolink:NamedThing	regulation of eosinophil migration	Any process that modulates the frequency, rate or extent of eosinophil migration.	got7fsn_ti							mah	2011-02-23T01:43:23Z						biological_process											owl:Class	
GO:0005416	biolink:NamedThing	amino acid:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in).	got7fsn_ti	cation:amino acid symporter activity|cation/amino acid symporter activity													molecular_function											owl:Class	
GO:0071300	biolink:NamedThing	cellular response to retinoic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.	got7fsn_ti	cellular response to vitamin A acid						mah	2009-12-10T04:30:34Z						biological_process											owl:Class	
GO:0002655	biolink:NamedThing	regulation of tolerance induction to nonself antigen	Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.	got7fsn_ti														biological_process											owl:Class	
GO:0042141	biolink:NamedThing	obsolete mating pheromone exporter	OBSOLETE. Exports diffusible peptide signals that are responsible for binding to other cells and triggering a series of responses to facilitate mating.	got7fsn_ti	mating pheromone exporter				This term was made obsolete because it is too gene product specific.	GO:0042626|GO:0043190				True				molecular_function											owl:Class	
GO:1905671	biolink:NamedThing	regulation of lysosome organization	Any process that modulates the frequency, rate or extent of lysosome organization.	got7fsn_ti	regulation of lysosome organisation|regulation of lysosome organization and biogenesis						sl	2016-11-11T22:01:04Z						biological_process											owl:Class	
GO:1990391	biolink:NamedThing	DNA repair complex	A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.	got7fsn_ti	WHY1 complex|DNA damage repair complex						bhm	2014-06-04T09:15:24Z						cellular_component											owl:Class	
GO:1903085	biolink:NamedThing	regulation of sinapate ester biosynthetic process	Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis.	got7fsn_ti	regulation of sinapate ester synthesis|regulation of sinapate ester formation|regulation of sinapate ester anabolism|regulation of sinapate ester biosynthesis						tb	2014-05-30T22:00:12Z						biological_process											owl:Class	
GO:0001971	biolink:NamedThing	negative regulation of activation of membrane attack complex	Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.	got7fsn_ti	down-regulation of activation of membrane attack complex|down regulation of activation of membrane attack complex|negative regulation of activation of the terminal complement cascade|negative regulation of MAC formation|negative regulation of activation of TCC|downregulation of activation of membrane attack complex|negative regulation of activation of MAC|negative regulation of membrane attack complex assembly|negative regulation of MAC assembly|inhibition of activation of membrane attack complex|negative regulation of membrane attack complex formation|negative regulation of activation of terminal complement complex													biological_process											owl:Class	
CHEBI:28856	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904186	biolink:NamedThing	post-anaphase microtubule array organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array.	got7fsn_ti	post-anaphase array organization|post-anaphase microtubule array organisation|PAA organization						mah	2015-05-05T14:40:16Z						biological_process											owl:Class	
GO:0046469	biolink:NamedThing	platelet activating factor metabolic process	The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.	got7fsn_ti	PAF metabolism|PAF metabolic process|platelet activating factor metabolism													biological_process											owl:Class	
GO:0061855	biolink:NamedThing	negative regulation of neuroblast migration	Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration.	got7fsn_ti							dph	2017-03-08T18:26:21Z						biological_process											owl:Class	
GO:0002267	biolink:NamedThing	follicular dendritic cell activation involved in immune response	A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	follicular dendritic cell activation during immune response													biological_process											owl:Class	
GO:0090344	biolink:NamedThing	negative regulation of cell aging	Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.	got7fsn_ti							tb	2010-06-02T10:12:37Z						biological_process											owl:Class	
GO:0002546	biolink:NamedThing	negative regulation of tissue kallikrein-kinin cascade	Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade.	got7fsn_ti	downregulation of tissue kallikrein-kinin cascade|negative regulation of glandular kallikrein-kinin cascade|inhibition of tissue kallikrein-kinin cascade|down regulation of tissue kallikrein-kinin cascade|down-regulation of tissue kallikrein-kinin cascade													biological_process											owl:Class	
GO:0001509	biolink:NamedThing	obsolete legumain activity	OBSOLETE. Catalysis of the hydrolysis of proteins and small-molecule substrates at Asn-Xaa bonds.	got7fsn_ti	PRSC1 gene product (Homo sapiens)|phaseolin activity|proteinase B|bean endopeptidase activity|hemoglobinase activity|vicilin peptidohydrolase activity|legumain activity|citvac|asparaginyl endopeptidase activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0061149	biolink:NamedThing	BMP signaling pathway involved in ureter morphogenesis	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder.	got7fsn_ti	BMP signalling pathway involved in ureter morphogenesis						dph	2010-06-02T09:11:46Z						biological_process											owl:Class	
GO:0019760	biolink:NamedThing	glucosinolate metabolic process	The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.	got7fsn_ti	glucosinolate metabolism													biological_process											owl:Class	
GO:0000258	biolink:NamedThing	obsolete isoleucine/valine:sodium symporter activity	OBSOLETE. Catalysis of the reaction: (isoleucine or valine)(out) + Na+(out) = (isoleucine or valine)(in) + Na+(in).	got7fsn_ti	isoleucine/valine:sodium symporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0005283|GO:0015188|GO:0005304				True				molecular_function											owl:Class	
GO:1900029	biolink:NamedThing	positive regulation of ruffle assembly	Any process that activates or increases the frequency, rate or extent of ruffle assembly.	got7fsn_ti	up regulation of ruffle assembly|up regulation of membrane ruffling|positive regulation of membrane ruffle formation|up regulation of membrane ruffle formation|positive regulation of membrane ruffling						yaf	2012-01-12T05:00:56Z						biological_process											owl:Class	
GO:0046366	biolink:NamedThing	allose biosynthetic process	The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	got7fsn_ti	allose biosynthesis|allose synthesis|allose formation|allose anabolism													biological_process											owl:Class	
GO:1901813	biolink:NamedThing	astaxanthin metabolic process	The chemical reactions and pathways involving astaxanthin.	got7fsn_ti	astaxanthin metabolism						yaf	2013-01-22T10:36:59Z						biological_process											owl:Class	
GO:0110118	biolink:NamedThing	negative regulation of compound eye photoreceptor cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.	got7fsn_ti							kmv	2018-07-16T18:15:52Z						biological_process											owl:Class	
GO:0010942	biolink:NamedThing	positive regulation of cell death	Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.	got7fsn_ti														biological_process											owl:Class	
GO:0045812	biolink:NamedThing	negative regulation of Wnt signaling pathway, calcium modulating pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).	got7fsn_ti	negative regulation of Wnt-activated signaling pathway, calcium modulating pathway|negative regulation of frizzled-2 signaling pathway|down-regulation of frizzled-2 signaling pathway|negative regulation of frizzled-2 signalling pathway|down regulation of frizzled-2 signaling pathway|inhibition of frizzled-2 signaling pathway|downregulation of frizzled-2 signaling pathway|negative regulation of Wnt receptor signaling pathway, calcium modulating pathway													biological_process											owl:Class	
GO:0031539	biolink:NamedThing	positive regulation of anthocyanin metabolic process	Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.	got7fsn_ti	up regulation of anthocyanin metabolic process|stimulation of anthocyanin metabolic process|up-regulation of anthocyanin metabolic process|positive regulation of anthocyanin metabolism|activation of anthocyanin metabolic process|upregulation of anthocyanin metabolic process													biological_process											owl:Class	
GO:0035947	biolink:NamedThing	obsolete regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of glucose biosynthesis by regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0051943	biolink:NamedThing	positive regulation of amino acid uptake involved in synaptic transmission	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.	got7fsn_ti	positive regulation of amino acid neurotransmitter uptake|activation of amino acid uptake during transmission of nerve impulse|up regulation of amino acid uptake during transmission of nerve impulse|up-regulation of amino acid uptake during transmission of nerve impulse|positive regulation of amino acid neurotransmitter reuptake|stimulation of amino acid uptake during transmission of nerve impulse|upregulation of amino acid uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0033184	biolink:NamedThing	positive regulation of histone ubiquitination	Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.	got7fsn_ti														biological_process											owl:Class	
GO:0055091	biolink:NamedThing	phospholipid homeostasis	Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0000097	biolink:NamedThing	sulfur amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.	got7fsn_ti	sulphur amino acid biosynthetic process|sulphur amino acid biosynthesis|sulfur amino acid anabolism|sulfur amino acid biosynthesis|sulfur amino acid formation|sulfur amino acid synthesis													biological_process											owl:Class	
GO:0043187	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046070	biolink:NamedThing	dGTP metabolic process	The chemical reactions and pathways involving dGTP, guanosine triphosphate.	got7fsn_ti	dGTP metabolism													biological_process											owl:Class	
GO:0010717	biolink:NamedThing	regulation of epithelial to mesenchymal transition	Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti														biological_process											owl:Class	
GO:0090043	biolink:NamedThing	regulation of tubulin deacetylation	Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.	got7fsn_ti							tb	2009-08-03T11:53:07Z						biological_process											owl:Class	
GO:0010710	biolink:NamedThing	regulation of collagen catabolic process	Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.	got7fsn_ti	regulation of collagen breakdown|regulation of collagen degradation|regulation of collagen catabolism													biological_process											owl:Class	
GO:0062132	biolink:NamedThing	regulation of L-glutamine biosynthetic process	Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis.	got7fsn_ti							dph	2019-06-27T13:44:21Z						biological_process											owl:Class	
CHEBI:28680	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000464	biolink:NamedThing	positive regulation of astrocyte chemotaxis	Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis.	got7fsn_ti							bf	2011-03-04T04:43:29Z						biological_process											owl:Class	
GO:0001937	biolink:NamedThing	negative regulation of endothelial cell proliferation	Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.	got7fsn_ti	down-regulation of endothelial cell proliferation|down regulation of endothelial cell proliferation|inhibition of endothelial cell proliferation|downregulation of endothelial cell proliferation													biological_process											owl:Class	
GO:0051544	biolink:NamedThing	positive regulation of elastin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.	got7fsn_ti	activation of elastin biosynthetic process|stimulation of elastin biosynthetic process|up-regulation of elastin biosynthetic process|up regulation of elastin biosynthetic process|upregulation of elastin biosynthetic process													biological_process											owl:Class	
GO:0031427	biolink:NamedThing	response to methotrexate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.	got7fsn_ti														biological_process											owl:Class	
GO:0017137	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051253	biolink:NamedThing	negative regulation of RNA metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.	got7fsn_ti	down-regulation of RNA metabolic process|down regulation of RNA metabolic process|inhibition of RNA metabolic process|downregulation of RNA metabolic process|negative regulation of RNA metabolism													biological_process											owl:Class	
GO:1902039	biolink:NamedThing	negative regulation of seed dormancy process	Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process.	got7fsn_ti	down regulation of seed dormancy process|down regulation of seed dormancy|down-regulation of seed dormancy process|downregulation of seed dormancy process|downregulation of seed dormancy|inhibition of seed dormancy|inhibition of seed dormancy process|down-regulation of seed dormancy|negative regulation of seed dormancy						tb	2013-04-02T22:13:15Z						biological_process											owl:Class	
GO:0016127	biolink:NamedThing	sterol catabolic process	The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	got7fsn_ti	sterol breakdown|sterol degradation|sterol catabolism													biological_process											owl:Class	
GO:1903619	biolink:NamedThing	negative regulation of transdifferentiation	Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation.	got7fsn_ti	down-regulation of transdifferentiation|downregulation of transdifferentiation|inhibition of transdifferentiation|down regulation of transdifferentiation						jl	2014-11-19T11:25:05Z						biological_process											owl:Class	
GO:0101023	biolink:NamedThing	vascular endothelial cell proliferation	The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population.	got7fsn_ti														biological_process											owl:Class	
CL:0011101	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075332	biolink:NamedThing	obsolete modulation by host of symbiont adenylate cyclase-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0002906	biolink:NamedThing	negative regulation of mature B cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.	got7fsn_ti	down-regulation of mature B cell apoptosis|inhibition of mature B cell apoptosis|downregulation of mature B cell apoptosis|negative regulation of mature B cell apoptosis|down regulation of mature B cell apoptosis													biological_process											owl:Class	
CHEBI:17126	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046517	biolink:NamedThing	octamethylcyclotetrasiloxane catabolic process	The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.	got7fsn_ti	octamethylcyclotetrasiloxane catabolism|octamethylcyclotetrasiloxane breakdown|octamethylcyclotetrasiloxane degradation													biological_process											owl:Class	
GO:0085013	biolink:NamedThing	obsolete interaction with host via protein secreted by type VII secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type VII secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:31:07Z		True				biological_process											owl:Class	
GO:0006149	biolink:NamedThing	deoxyinosine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside.	got7fsn_ti	deoxyinosine degradation|deoxyinosine catabolism|deoxyinosine breakdown													biological_process											owl:Class	
GO:0051122	biolink:NamedThing	hepoxilin biosynthetic process	The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.	got7fsn_ti	hepoxilin synthesis|hepoxilin biosynthesis|hepoxilin anabolism|hepoxilin formation													biological_process											owl:Class	
GO:2000796	biolink:NamedThing	Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment	Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment.	got7fsn_ti	Notch receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment|N signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch signalling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch-receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch-receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment						bf	2011-06-27T09:07:42Z						biological_process											owl:Class	
GO:0045865	biolink:NamedThing	obsolete regulation of recombination within rDNA repeats	OBSOLETE. Any process that modulates the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.	got7fsn_ti	regulation of recombination within rDNA repeats			GO:0000019	This term was made obsolete because it describes a substrate-specific process.					True				biological_process											owl:Class	
GO:0070578	biolink:NamedThing	RISC-loading complex	A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity.	got7fsn_ti	microRNA loading complex|miRLC|RLC						mah	2009-04-22T01:40:19Z						cellular_component											owl:Class	
GO:1902050	biolink:NamedThing	neosartoricin biosynthetic process	The chemical reactions and pathways resulting in the formation of neosartoricin.	got7fsn_ti	neosartoricin anabolism|neosartoricin biosynthesis|neosartoricin synthesis|neosartoricin formation						di	2013-04-08T20:31:11Z						biological_process											owl:Class	
GO:1990497	biolink:NamedThing	regulation of cytoplasmic translation in response to stress	Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti							vw	2014-09-26T11:11:29Z						biological_process											owl:Class	
CL:0000679	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904375	biolink:NamedThing	regulation of protein localization to cell periphery	Any process that modulates the frequency, rate or extent of protein localization to cell periphery.	got7fsn_ti							sl	2015-06-22T22:09:25Z						biological_process											owl:Class	
GO:0003005	biolink:NamedThing	follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage	The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis.	got7fsn_ti	follicular fluid formation in ovarian follicle antrum during scattered antral spaces stage													biological_process											owl:Class	
GO:0002871	biolink:NamedThing	regulation of natural killer cell tolerance induction	Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.	got7fsn_ti	regulation of NK cell tolerance induction													biological_process											owl:Class	
GO:1902179	biolink:NamedThing	verruculogen metabolic process	The chemical reactions and pathways involving verruculogen.	got7fsn_ti	verruculogen metabolism						di	2013-05-30T17:44:25Z						biological_process											owl:Class	
GO:0019526	biolink:NamedThing	pentitol biosynthetic process	The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule.	got7fsn_ti	pentitol formation|pentitol biosynthesis|pentitol anabolism|pentitol synthesis													biological_process											owl:Class	
GO:0010800	biolink:NamedThing	positive regulation of peptidyl-threonine phosphorylation	Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	got7fsn_ti														biological_process											owl:Class	
GO:1900058	biolink:NamedThing	regulation of sulfate assimilation	Any process that modulates the frequency, rate or extent of sulfate assimilation.	got7fsn_ti	regulation of sulphate assimilation|regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor						dph	2012-01-25T03:14:40Z						biological_process											owl:Class	
CHEBI:39446	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016134	biolink:NamedThing	saponin metabolic process	The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.	got7fsn_ti	saponin metabolism													biological_process											owl:Class	
GO:0033383	biolink:NamedThing	geranyl diphosphate metabolic process	The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.	got7fsn_ti	geranyl diphosphate metabolism|geranyldiphosphate metabolic process													biological_process											owl:Class	
GO:1902311	biolink:NamedThing	regulation of copper ion transmembrane transport	Any process that modulates the frequency, rate or extent of copper ion transmembrane transport.	got7fsn_ti	regulation of copper cation transmembrane transport|regulation of copper ion membrane transport						di	2013-07-19T20:59:28Z						biological_process											owl:Class	
GO:0150167	biolink:NamedThing	positive regulation of histone H3-K4 acetylation	Any process that activates or increases the frequency, rate or extent of histone H3-K4 acetylation.	got7fsn_ti							bc	2020-01-14T12:32:18Z						biological_process											owl:Class	
CHEBI:58341	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060823	biolink:NamedThing	canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.	got7fsn_ti	canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation|canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation|canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation						dph	2009-08-11T01:22:42Z						biological_process											owl:Class	
GO:0072668	biolink:NamedThing	obsolete tubulin complex biogenesis	OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a tubulin complex. Includes the synthesis and folding of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. A tubulin complex is a heterodimer of tubulins alpha and beta, from which microtubules are assembled.	got7fsn_ti	tubulin complex biogenesis			GO:0007021	This term was obsoleted because biogenesis should only be used for complexes where synthesis of some non-protein component is necessary for assembly.		mah	2011-02-14T03:25:18Z		True				biological_process											owl:Class	
GO:0046078	biolink:NamedThing	dUMP metabolic process	The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate).	got7fsn_ti	dUMP metabolism													biological_process											owl:Class	
GO:0090318	biolink:NamedThing	regulation of chylomicron remodeling	Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.	got7fsn_ti							tb	2010-04-30T10:09:08Z						biological_process											owl:Class	
CHEBI:60924	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075300	biolink:NamedThing	negative regulation of zygospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0032555	biolink:NamedThing	purine ribonucleotide binding	Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	got7fsn_ti														molecular_function											owl:Class	
GO:1902502	biolink:NamedThing	multivesicular body HOPS complex	Any HOPS complex that is part of a multivesicular body membrane.	got7fsn_ti	multivesicular body membrane HOPS complex						tb	2013-11-14T00:10:08Z						cellular_component											owl:Class	
GO:0032078	biolink:NamedThing	negative regulation of endodeoxyribonuclease activity	Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	got7fsn_ti	down-regulation of endodeoxyribonuclease activity|down regulation of endodeoxyribonuclease activity|endodeoxyribonuclease inhibitor|downregulation of endodeoxyribonuclease activity|inhibition of endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0015959	biolink:NamedThing	diadenosine polyphosphate metabolic process	The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.	got7fsn_ti	diadenosine polyphosphate metabolism													biological_process											owl:Class	
GO:2000675	biolink:NamedThing	negative regulation of type B pancreatic cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.	got7fsn_ti	negative regulation of pancreatic B cell apoptosis|negative regulation of type B pancreatic cell apoptosis|negative regulation of pancreatic beta cell apoptosis						pr	2011-05-09T11:51:12Z						biological_process											owl:Class	
GO:1990695	biolink:NamedThing	intrinsic component of Golgi trans cisterna membrane	The component of the Golgi trans cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic component of trans-Golgi cisterna membrane						bhm	2015-03-12T10:36:02Z						cellular_component											owl:Class	
GO:0100060	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by DNA binding	OBSOLETE. Any DNA binding that negatively regulates SREBP signaling pathway.	got7fsn_ti					The reason for obsoletion is that this term should be represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				molecular_function											owl:Class	
CHEBI:37563	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901325	biolink:NamedThing	response to antimycin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.	got7fsn_ti							mah	2012-08-30T10:12:16Z						biological_process											owl:Class	
GO:2000313	biolink:NamedThing	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.	got7fsn_ti	regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation						vk	2011-01-18T10:26:22Z						biological_process											owl:Class	
CHEBI:26355	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000466	biolink:NamedThing	negative regulation of glycogen (starch) synthase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity.	got7fsn_ti	negative regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|negative regulation of UDP-glucose-glycogen glucosyltransferase activity|negative regulation of UDPG-glycogen transglucosylase activity|negative regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|negative regulation of UDPG-glycogen synthetase activity|negative regulation of glycogen (starch) synthetase activity|negative regulation of UDP-glycogen synthase activity|negative regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity						yaf	2011-03-07T04:13:14Z						biological_process											owl:Class	
GO:1904682	biolink:NamedThing	cellular response to 3-methylcholanthrene	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.	got7fsn_ti							mr	2015-09-22T19:50:10Z						biological_process											owl:Class	
GO:0019308	biolink:NamedThing	dTDP-mannose biosynthetic process	The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.	got7fsn_ti	dTDP-mannose anabolism|dTDP-mannose synthesis|dTDP-mannose biosynthesis|dTDP-mannose formation													biological_process											owl:Class	
GO:0030973	biolink:NamedThing	molybdate ion binding	Binding to a molybdate ion (MoO4 2-).	got7fsn_ti	MoO4 ion binding													molecular_function											owl:Class	
GO:0072719	biolink:NamedThing	cellular response to cisplatin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.	got7fsn_ti							mah	2012-04-30T11:31:12Z						biological_process											owl:Class	
GO:0007468	biolink:NamedThing	obsolete regulation of rhodopsin gene expression	OBSOLETE. Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation.	got7fsn_ti	regulation of rhodopsin gene activity				This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0006357				True				biological_process											owl:Class	
GO:0090281	biolink:NamedThing	negative regulation of calcium ion import	Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.	got7fsn_ti	negative regulation of transmembrane calcium influx						tb	2010-02-08T05:11:20Z						biological_process											owl:Class	
GO:0009177	biolink:NamedThing	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside monophosphate anabolism|pyrimidine deoxyribonucleoside monophosphate biosynthesis|pyrimidine deoxyribonucleoside monophosphate formation|pyrimidine deoxyribonucleoside monophosphate synthesis													biological_process											owl:Class	
GO:1990545	biolink:NamedThing	mitochondrial thiamine pyrophosphate transmembrane transport	The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T11:47:15Z						biological_process											owl:Class	
GO:1990241	biolink:NamedThing	obsolete nucleotide binding complex	OBSOLETE. A protein complex that interacts selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. An example of this is STING in E. coli (Q86WV6).	got7fsn_ti	nucleotide binding complex				This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2013-11-22T16:22:07Z		True				cellular_component											owl:Class	
GO:1904831	biolink:NamedThing	positive regulation of aortic smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.	got7fsn_ti	up regulation of aortic smooth muscle cell differentiation|up-regulation of aortic smooth muscle cell differentiation|activation of aortic smooth muscle cell differentiation|upregulation of aortic smooth muscle cell differentiation						rph	2015-11-24T10:20:54Z						biological_process											owl:Class	
GO:1902259	biolink:NamedThing	regulation of delayed rectifier potassium channel activity	Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity.	got7fsn_ti							rl	2013-06-25T12:16:19Z						biological_process											owl:Class	
GO:0097403	biolink:NamedThing	cellular response to raffinose	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.	got7fsn_ti							pr	2012-10-29T10:30:46Z						biological_process											owl:Class	
GO:1905716	biolink:NamedThing	negative regulation of cornification	Any process that stops, prevents or reduces the frequency, rate or extent of cornification.	got7fsn_ti	inhibition of cornification|down regulation of cornification|downregulation of cornification|down-regulation of cornification						pga	2016-11-24T13:53:03Z						biological_process											owl:Class	
GO:0060372	biolink:NamedThing	regulation of atrial cardiac muscle cell membrane repolarization	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte.	got7fsn_ti	regulation of atrial cardiac muscle cell repolarization|atrial repolarization|electrocardiogram QRS complex|regulation of atrial cardiomyocyte membrane repolarization													biological_process											owl:Class	
GO:2000793	biolink:NamedThing	cell proliferation involved in heart valve development	Any cell proliferation that is involved in heart valve development.	got7fsn_ti	cell proliferation of heart valve development|cell proliferation of cardiac valve development						bf	2011-06-24T03:12:15Z						biological_process											owl:Class	
GO:1903968	biolink:NamedThing	cellular response to micafungin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.	got7fsn_ti							al	2015-02-27T09:57:44Z						biological_process											owl:Class	
GO:0015336	biolink:NamedThing	obsolete high affinity metal ion uptake transporter activity	OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Fe2+, Mn2+, Zn2+, Cu2+, Cd2+, Ni2+ or Co2+.	got7fsn_ti	high affinity metal ion uptake transporter activity				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0015295|GO:0046873				True				molecular_function											owl:Class	
FAO:0000026	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903576	biolink:NamedThing	response to L-arginine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.	got7fsn_ti							mr	2014-10-29T22:18:39Z						biological_process											owl:Class	
GO:0042866	biolink:NamedThing	pyruvate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate.	got7fsn_ti	pyruvate anabolism|pyruvate formation|pyruvate biosynthesis|pyruvate synthesis													biological_process											owl:Class	
GO:0052244	biolink:NamedThing	obsolete negative energy taxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative energy taxis in other organism during symbiotic interaction|negative energy taxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0019555	biolink:NamedThing	glutamate catabolic process to ornithine	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine.	got7fsn_ti	glutamate breakdown to ornithine|glutamate degradation to ornithine											MetaCyc:GLUTORN-PWY		biological_process											owl:Class	
GO:0097336	biolink:NamedThing	response to risperidone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.	got7fsn_ti							pr	2012-06-12T11:04:31Z						biological_process											owl:Class	
GO:1903651	biolink:NamedThing	positive regulation of cytoplasmic transport	Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.	got7fsn_ti	upregulation of cytoplasmic transport|up regulation of cytoplasmic streaming|activation of cytoplasmic transport|up-regulation of cytoplasmic streaming|up regulation of cytoplasmic transport|up-regulation of cytoplasmic transport|activation of cytoplasmic streaming|upregulation of cytoplasmic streaming|positive regulation of cytoplasmic streaming						jl	2014-11-24T13:38:34Z						biological_process											owl:Class	
GO:0005331	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001579	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905162	biolink:NamedThing	regulation of phagosome maturation	Any process that modulates the frequency, rate or extent of phagosome maturation.	got7fsn_ti							bf	2016-04-25T16:28:03Z						biological_process											owl:Class	
GO:0010193	biolink:NamedThing	response to ozone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:1901065	biolink:NamedThing	syringal lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of syringal lignin.	got7fsn_ti	syringal lignin degradation|syringal lignin catabolism|S-lignin catabolic process|syringal lignin breakdown						tt	2012-06-29T03:48:33Z						biological_process											owl:Class	
GO:0071895	biolink:NamedThing	odontoblast differentiation	The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.	got7fsn_ti							mah	2010-09-14T04:00:40Z						biological_process											owl:Class	
GO:1904086	biolink:NamedThing	regulation of epiboly involved in gastrulation with mouth forming second	Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.	got7fsn_ti							dos	2015-03-25T11:17:34Z						biological_process											owl:Class	
GO:1905498	biolink:NamedThing	positive regulation of triplex DNA binding	Any process that activates or increases the frequency, rate or extent of triplex DNA binding.	got7fsn_ti	upregulation of triplex DNA binding|activation of triplex DNA binding|up regulation of triplex DNA binding|up-regulation of triplex DNA binding						ans	2016-09-26T14:57:25Z						biological_process											owl:Class	
GO:0015390	biolink:NamedThing	purine-specific nucleoside:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0005564	biolink:NamedThing	obsolete cytosolic tRNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytosolic tRNA				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0033633	biolink:NamedThing	negative regulation of cell-cell adhesion mediated by integrin	Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.	got7fsn_ti	negative regulation of cell-cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0071441	biolink:NamedThing	negative regulation of histone H3-K14 acetylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.	got7fsn_ti	negative regulation of histone H3K14 acetylation|down-regulation of histone H3-K14 acetylation|inhibition of histone H3-K14 acetylation|downregulation of histone H3-K14 acetylation|negative regulation of histone H3 acetylation at K14|down regulation of histone H3-K14 acetylation						mah	2009-12-16T03:28:23Z						biological_process											owl:Class	
GO:2000653	biolink:NamedThing	regulation of genetic imprinting	Any process that modulates the frequency, rate or extent of genetic imprinting.	got7fsn_ti	regulation of DNA imprinting						vk	2011-04-30T02:42:19Z						biological_process											owl:Class	
GO:1902898	biolink:NamedThing	fatty acid methyl ester metabolic process	The chemical reactions and pathways involving fatty acid methyl ester.	got7fsn_ti	FAME metabolic process|fatty acid methyl ester metabolism						tt	2014-04-11T03:08:34Z						biological_process											owl:Class	
GO:0019388	biolink:NamedThing	galactose catabolic process	The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.	got7fsn_ti	galactose breakdown|galactose degradation|galactose catabolism											MetaCyc:GALDEG-PWY		biological_process											owl:Class	
CHEBI:41808	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900517	biolink:NamedThing	positive regulation of xylose catabolic process to ethanol	Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol.	got7fsn_ti	positive regulation of xylose catabolism to ethanol|up regulation of xylose catabolism to ethanol|up regulation of xylose catabolic process to ethanol|upregulation of xylose catabolism to ethanol|upregulation of xylose catabolic process to ethanol|activation of xylose catabolic process to ethanol|activation of xylose catabolism to ethanol|up-regulation of xylose catabolism to ethanol|up-regulation of xylose catabolic process to ethanol						tt	2012-05-02T04:09:26Z						biological_process											owl:Class	
GO:0003256	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.	got7fsn_ti							dph	2009-10-15T01:01:25Z						biological_process											owl:Class	
GO:1904529	biolink:NamedThing	regulation of actin filament binding	Any process that modulates the frequency, rate or extent of actin filament binding.	got7fsn_ti	regulation of actin cross-linking activity|regulation of F-actin binding						als	2015-07-30T10:41:49Z						biological_process											owl:Class	
GO:0052478	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont cell wall callose deposition	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of defense-related symbiont cell wall callose deposition				This term was made obsolete because it does not represent a valid biological process that occurs in nature.					True				biological_process											owl:Class	
GO:0062058	biolink:NamedThing	transcription factor TFIIH holo complex binding	Binding to a transcription factor TFIIH holo complex.	got7fsn_ti							dph	2018-08-31T13:44:17Z						molecular_function											owl:Class	
GO:0042964	biolink:NamedThing	obsolete thioredoxin reduction	OBSOLETE. The chemical reactions and pathways resulting in the reduction of thioredoxin, a small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase.	got7fsn_ti	thioredoxin formation|thioredoxin anabolism|thioredoxin biosynthesis|thioredoxin synthesis	https://github.com/geneontology/go-ontology/issues/20250			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0015864	biolink:NamedThing	pyrimidine nucleoside transport	The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0030839	biolink:NamedThing	regulation of intermediate filament polymerization	Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament.	got7fsn_ti														biological_process											owl:Class	
GO:0031590	biolink:NamedThing	wybutosine metabolic process	The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.	got7fsn_ti	wybutosine metabolism|yW metabolic process|yW metabolism													biological_process											owl:Class	
GO:0033287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006068	biolink:NamedThing	ethanol catabolic process	The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.	got7fsn_ti	ethanol degradation|ethanol breakdown|ethanol catabolism													biological_process											owl:Class	
CHEBI:16389	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030291	biolink:NamedThing	protein serine/threonine kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a protein serine/threonine kinase.	got7fsn_ti														molecular_function											owl:Class	
GO:0071527	biolink:NamedThing	semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.	got7fsn_ti	semaphorin-plexin signalling pathway involved in outflow tract morphogenesis						mah	2010-01-07T03:49:33Z						biological_process											owl:Class	
GO:0031677	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002725	biolink:NamedThing	negative regulation of T cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.	got7fsn_ti	inhibition of T cell cytokine production|downregulation of T cell cytokine production|negative regulation of T-cell cytokine production|down regulation of T cell cytokine production|negative regulation of T lymphocyte cytokine production|down-regulation of T cell cytokine production|negative regulation of T-lymphocyte cytokine production													biological_process											owl:Class	
GO:0075245	biolink:NamedThing	positive regulation of oospore formation	Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.	got7fsn_ti														biological_process											owl:Class	
GO:0046102	biolink:NamedThing	inosine metabolic process	The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.	got7fsn_ti	inosine metabolism													biological_process											owl:Class	
GO:1902547	biolink:NamedThing	regulation of cellular response to vascular endothelial growth factor stimulus	Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.	got7fsn_ti	regulation of cellular response to VEGFA|regulation of cellular response to vascular endothelial growth factor|regulation of cellular response to VEGF|regulation of cellular response to VEGFB						rl	2013-12-04T15:14:54Z						biological_process											owl:Class	
GO:0002586	biolink:NamedThing	regulation of antigen processing and presentation of peptide antigen via MHC class II	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.	got7fsn_ti	regulation of peptide antigen processing and presentation via MHC class II													biological_process											owl:Class	
CHEBI:4911	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900431	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to heat	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.	got7fsn_ti							di	2012-04-25T05:54:05Z						biological_process											owl:Class	
GO:1901779	biolink:NamedThing	pentalenolactone catabolic process	The chemical reactions and pathways resulting in the breakdown of pentalenolactone.	got7fsn_ti	pentalenolactone degradation|pentalenolactone catabolism|pentalenolactone breakdown						yaf	2013-01-16T09:49:42Z						biological_process											owl:Class	
GO:0010984	biolink:NamedThing	regulation of lipoprotein particle clearance	Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							tb	2009-06-01T12:05:12Z						biological_process											owl:Class	
CHEBI:16189	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019296	biolink:NamedThing	coenzyme M metabolic process	The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.	got7fsn_ti	coenzyme M metabolism													biological_process											owl:Class	
GO:1901284	biolink:NamedThing	5,6,7,8-tetrahydromethanopterin catabolic process	The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin.	got7fsn_ti	5,6,7,8-tetrahydromethanopterin degradation|5,6,7,8-tetrahydromethanopterin catabolism|5,6,7,8-tetrahydromethanopterin breakdown						yaf	2012-08-17T15:32:54Z						biological_process											owl:Class	
GO:0033481	biolink:NamedThing	galacturonate biosynthetic process	The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid.	got7fsn_ti	galacturonate biosynthesis|galacturonate anabolism|galacturonate formation|galacturonate synthesis													biological_process											owl:Class	
GO:0033021	biolink:NamedThing	cyclopentanol biosynthetic process	The chemical reactions and pathways resulting in the formation of cyclopentanol.	got7fsn_ti	cyclopentanol formation|cyclopentanol anabolism|cyclopentanol biosynthesis|cyclopentanol synthesis													biological_process											owl:Class	
GO:1903477	biolink:NamedThing	mitotic contractile ring actin filament bundle assembly	Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti	actin filament bundle assembly involved in mitotic actomyosin contractile ring assembly						vw	2014-09-23T14:56:01Z						biological_process											owl:Class	
GO:0061398	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to copper ion	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0071280|GO:0000122	dph	2012-01-10T09:17:02Z		True				biological_process											owl:Class	
GO:0070494	biolink:NamedThing	regulation of thrombin-activated receptor signaling pathway	Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.	got7fsn_ti	regulation of thrombin receptor signaling pathway|regulation of thrombin receptor signalling pathway													biological_process											owl:Class	
GO:1901971	biolink:NamedThing	regulation of DNA-5-methylcytosine glycosylase activity	Any process that modulates the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity.	got7fsn_ti							tb	2013-02-25T20:01:29Z						biological_process											owl:Class	
GO:1904204	biolink:NamedThing	regulation of skeletal muscle hypertrophy	Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy.	got7fsn_ti							sl	2015-05-08T17:38:13Z						biological_process											owl:Class	
OBO:OBA_0000093	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901815	biolink:NamedThing	astaxanthin biosynthetic process	The chemical reactions and pathways resulting in the formation of astaxanthin.	got7fsn_ti	astaxanthin synthesis|astaxanthin anabolism|astaxanthin formation|astaxanthin biosynthesis						yaf	2013-01-22T10:37:11Z						biological_process											owl:Class	
CHEBI:17754	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019436	biolink:NamedThing	sophorosyloxydocosanoate catabolic process	The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.	got7fsn_ti	sophorosyloxydocosanoate catabolism|sophorosyloxydocosanoate degradation|sophorosyloxydocosanoate breakdown											MetaCyc:SOPHOROSYLOXYDOCOSANOATE-DEG-PWY		biological_process											owl:Class	
GO:2001113	biolink:NamedThing	negative regulation of cellular response to hepatocyte growth factor stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.	got7fsn_ti	negative regulation of cellular response to HGF stimulus						dph	2011-10-05T05:43:23Z						biological_process											owl:Class	
GO:0010925	biolink:NamedThing	positive regulation of inositol-polyphosphate 5-phosphatase activity	Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0036280	biolink:NamedThing	cellular response to L-canavanine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group.	got7fsn_ti							bf	2012-07-11T11:09:37Z						biological_process											owl:Class	
GO:0100057	biolink:NamedThing	obsolete regulation of phenotypic switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates phenotypic switching.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0033226	biolink:NamedThing	2-aminoethylphosphonate binding	Binding to 2-aminoethylphosphonate.	got7fsn_ti	2-phosphonoethylamine binding|ciliatine binding													molecular_function											owl:Class	
GO:1904325	biolink:NamedThing	positive regulation of inhibitory G protein-coupled receptor phosphorylation	Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.	got7fsn_ti	up-regulation of inhibitory G-protein coupled receptor phosphorylation|upregulation of inhibitory G-protein coupled receptor phosphorylation|positive regulation of inhibitory G-protein coupled receptor phosphorylation|up regulation of inhibitory G-protein coupled receptor phosphorylation|activation of inhibitory G-protein coupled receptor phosphorylation						sl	2015-06-10T19:46:50Z						biological_process											owl:Class	
GO:1904853	biolink:NamedThing	protein localization to ascospore wall	A process in which a protein is transported to, or maintained in, a location within an ascospore wall.	got7fsn_ti	protein localisation in ascospore wall|protein localization in ascospore wall|protein localisation to ascospore wall						mah	2015-12-14T12:52:50Z						biological_process											owl:Class	
GO:0051125	biolink:NamedThing	regulation of actin nucleation	Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.	got7fsn_ti														biological_process											owl:Class	
GO:0052435	biolink:NamedThing	obsolete modulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation of defense-related symbiont MAPK-mediated signal transduction pathway by organism|modulation of defense-related symbiont mitogen activated protein kinase-mediated signal transduction pathway by organism				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0005561	biolink:NamedThing	obsolete nucleic acid	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nucleic acid				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0002888	biolink:NamedThing	positive regulation of myeloid leukocyte mediated immunity	Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.	got7fsn_ti	activation of myeloid leukocyte mediated immunity|up regulation of myeloid leukocyte mediated immunity|up-regulation of myeloid leukocyte mediated immunity|stimulation of myeloid leukocyte mediated immunity|upregulation of myeloid leukocyte mediated immunity													biological_process											owl:Class	
GO:1903131	biolink:NamedThing	mononuclear cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.	got7fsn_ti							cls	2014-06-25T15:47:09Z						biological_process											owl:Class	
GO:0005763	biolink:NamedThing	mitochondrial small ribosomal subunit	The smaller of the two subunits of a mitochondrial ribosome.	got7fsn_ti	28S ribosomal subunit, mitochondrial|mitochondrial ribosomal small subunit complex|mitochondrial ribosomal SSU complex													cellular_component											owl:Class	
GO:0007047	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016102	biolink:NamedThing	diterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.	got7fsn_ti	diterpenoid formation|diterpene biosynthetic process|diterpenoid biosynthesis|diterpenoid anabolism|diterpene biosynthesis|diterpenoid synthesis													biological_process											owl:Class	
GO:0102026	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903009	biolink:NamedThing	proteasome complex disassembly	The disaggregation of a proteasome complex into its constituent components.	got7fsn_ti	26S proteasome disassembly|proteasome degradation|proteasome disassembly						jl	2014-05-13T12:41:59Z						biological_process											owl:Class	
GO:0046325	biolink:NamedThing	negative regulation of glucose import	Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.	got7fsn_ti	down-regulation of glucose import|inhibition of glucose import|downregulation of glucose import|negative regulation of glucose uptake|down regulation of glucose import													biological_process											owl:Class	
GO:0140408	biolink:NamedThing	regulation of mRNA alternative polyadenylation	Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15389					pg	2019-12-13T12:48:14Z						biological_process											owl:Class	
GO:0002762	biolink:NamedThing	negative regulation of myeloid leukocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.	got7fsn_ti	down-regulation of myeloid leukocyte differentiation|down regulation of myeloid leukocyte differentiation|downregulation of myeloid leukocyte differentiation|inhibition of myeloid leukocyte differentiation													biological_process											owl:Class	
GO:0045651	biolink:NamedThing	positive regulation of macrophage differentiation	Any process that activates or increases the frequency, rate or extent of macrophage differentiation.	got7fsn_ti	upregulation of macrophage differentiation|activation of macrophage differentiation|stimulation of macrophage differentiation|up-regulation of macrophage differentiation|up regulation of macrophage differentiation													biological_process											owl:Class	
GO:2001199	biolink:NamedThing	negative regulation of dendritic cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.	got7fsn_ti							yaf	2011-11-04T02:01:33Z						biological_process											owl:Class	
GO:0031558	biolink:NamedThing	obsolete induction of apoptosis in response to chemical stimulus	OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus.	got7fsn_ti	induction of apoptosis in response to chemical stimulus|induction of apoptosis in response to chemical substance				This term was made obsolete because it is now superseded by better defined and more specific terms under the node of GO:0006915 apoptotic process.					True				biological_process											owl:Class	
GO:0022843	biolink:NamedThing	voltage-gated cation channel activity	Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti												Reactome:R-HSA-6788999|Reactome:R-HSA-2534378		molecular_function											owl:Class	
GO:0000259	biolink:NamedThing	obsolete intracellular nucleoside transmembrane transporter activity	OBSOLETE. Enables the directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide) within a cell.	got7fsn_ti	intracellular nucleoside transmembrane transporter activity				This term was made obsolete because it contains component and function information.	GO:0005337|GO:0005622				True				molecular_function											owl:Class	
GO:1902528	biolink:NamedThing	regulation of protein linear polyubiquitination	Any process that modulates the frequency, rate or extent of protein linear polyubiquitination.	got7fsn_ti	regulation of M1 linkage						ppm	2013-12-02T10:03:00Z						biological_process											owl:Class	
CHEBI:16240	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002618	biolink:NamedThing	positive regulation of macrophage antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.	got7fsn_ti	upregulation of macrophage antigen processing and presentation|activation of macrophage antigen processing and presentation|up regulation of macrophage antigen processing and presentation|stimulation of macrophage antigen processing and presentation|up-regulation of macrophage antigen processing and presentation													biological_process											owl:Class	
GO:2001314	biolink:NamedThing	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process	The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.	got7fsn_ti	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose breakdown|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolism|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose degradation						pr	2012-03-22T01:20:01Z						biological_process											owl:Class	
UBERON:0002303	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044371	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015326	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000755	biolink:NamedThing	positive regulation of sphingomyelin catabolic process	Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process.	got7fsn_ti	positive regulation of sphingomyelin breakdown|positive regulation of sphingomyelin degradation|positive regulation of sphingomyelin catabolism						rl	2011-06-16T03:17:35Z						biological_process											owl:Class	
GO:1903254	biolink:NamedThing	hercynylselenocysteine metabolic process	The chemical reactions and pathways involving hercynylselenocysteine.	got7fsn_ti	hercynylselenocysteine metabolism						mah	2014-08-06T09:14:08Z						biological_process											owl:Class	
GO:0017163	biolink:NamedThing	obsolete basal transcription repressor activity	OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.	got7fsn_ti	basal transcription repressor activity				This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001227|GO:0001217|GO:0045892				True				molecular_function											owl:Class	
GO:0150117	biolink:NamedThing	positive regulation of cell-substrate junction organization	Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization.	got7fsn_ti							bc	2019-11-14T12:15:07Z						biological_process											owl:Class	
GO:0004261	biolink:NamedThing	obsolete cathepsin G activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to chymotrypsin C.	got7fsn_ti	chymotrypsin-like proteinase activity|neutral proteinase activity|cathepsin G activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1901494	biolink:NamedThing	regulation of cysteine metabolic process	Any process that modulates the frequency, rate or extent of cysteine metabolic process.	got7fsn_ti	regulation of cysteine metabolism						vw	2012-10-16T14:28:42Z						biological_process											owl:Class	
GO:2000728	biolink:NamedThing	regulation of mRNA export from nucleus in response to heat stress	Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress.	got7fsn_ti	regulation of mRNA export from nucleus during heat stress|regulation of mRNA export from cell nucleus during heat stress						pr	2011-06-08T12:17:45Z						biological_process											owl:Class	
GO:0062230	biolink:NamedThing	negative regulation of larval somatic muscle development	Any process that decreases the rate, frequency or extent of larval somatic muscle development.	got7fsn_ti							dph	2020-03-16T13:46:48Z						biological_process											owl:Class	
GO:0006840	biolink:NamedThing	obsolete mitochondrial alpha-ketoglutarate/malate transport	OBSOLETE. The directed movement of alpha-ketoglutarate and malate into, out of or within a mitochondrion.	got7fsn_ti	mitochondrial alpha-ketoglutarate/malate transport|mitochondrial oxoglutarate/malate transport				This term was made obsolete because it represents a function rather than a process.	GO:0015743|GO:0015742|GO:0015367|GO:0006839				True				biological_process											owl:Class	
GO:0098937	biolink:NamedThing	anterograde dendritic transport	The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites.	got7fsn_ti														biological_process											owl:Class	
CHEBI:50169	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901823	biolink:NamedThing	delta-carotene catabolic process	The chemical reactions and pathways resulting in the breakdown of delta-carotene.	got7fsn_ti	delta-carotene catabolism|delta-carotene degradation|delta-carotene breakdown						yaf	2013-01-22T11:17:34Z						biological_process											owl:Class	
GO:0043900	biolink:NamedThing	obsolete regulation of multi-organism process	OBSOLETE. Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.	got7fsn_ti					This term was obsoleted because it is an unnecessary grouping term.					True				biological_process											owl:Class	
GO:1901114	biolink:NamedThing	erythromycin catabolic process	The chemical reactions and pathways resulting in the breakdown of erythromycin.	got7fsn_ti	erythromycin catabolism|erythromycin degradation|erythromycin breakdown						yaf	2012-07-11T03:06:38Z						biological_process											owl:Class	
GO:1900701	biolink:NamedThing	regulation of orcinol biosynthetic process	Any process that modulates the frequency, rate or extent of orcinol biosynthetic process.	got7fsn_ti	regulation of orcinol anabolism|regulation of orcinol formation|regulation of orcinol synthesis|regulation of orcinol biosynthesis						di	2012-05-22T04:57:59Z						biological_process											owl:Class	
GO:0052421	biolink:NamedThing	obsolete metabolism by organism of xylan in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism by organism of xylan in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was deprecated because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:0106220	biolink:NamedThing	pyocyanine biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group.	got7fsn_ti	pyocyanin biosynthetic process						hjd	2019-08-19T17:15:48Z						biological_process											owl:Class	
GO:0035024	biolink:NamedThing	negative regulation of Rho protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.	got7fsn_ti	down-regulation of Rho protein signal transduction|inhibition of Rho protein signal transduction|down regulation of Rho protein signal transduction|downregulation of Rho protein signal transduction													biological_process											owl:Class	
GO:0035773	biolink:NamedThing	insulin secretion involved in cellular response to glucose stimulus	The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.	got7fsn_ti	insulin secretion involved in cellular response to glucose						bf	2011-04-01T01:14:40Z						biological_process											owl:Class	
GO:1901696	biolink:NamedThing	cannabinoid biosynthetic process	The chemical reactions and pathways resulting in the formation of cannabinoid.	got7fsn_ti	cannabinoid anabolism|cannabinoid formation|cannabinoid synthesis|cannabinoid biosynthesis						ms	2012-12-13T08:07:47Z						biological_process											owl:Class	
GO:0046041	biolink:NamedThing	ITP metabolic process	The chemical reactions and pathways involving ITP, inosine triphosphate.	got7fsn_ti	ITP metabolism													biological_process											owl:Class	
GO:0033640	biolink:NamedThing	modulation by symbiont of host response to osmotic stress	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0010829	biolink:NamedThing	negative regulation of glucose transmembrane transport	Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	negative regulation of glucose transport													biological_process											owl:Class	
GO:0010046	biolink:NamedThing	response to mycotoxin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0045344	biolink:NamedThing	negative regulation of MHC class I biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.	got7fsn_ti	negative regulation of MHC class I synthesis|negative regulation of MHC class I anabolism|down regulation of MHC class I biosynthetic process|negative regulation of MHC class I formation|negative regulation of MHC class I biosynthesis|down-regulation of MHC class I biosynthetic process|downregulation of MHC class I biosynthetic process|negative regulation of major histocompatibility complex class I biosynthesis|inhibition of MHC class I biosynthetic process|negative regulation of major histocompatibility complex class I biosynthetic process													biological_process											owl:Class	
GO:0032899	biolink:NamedThing	regulation of neurotrophin production	Any process that modulates the frequency, rate, or extent of production of a neurotrophin.	got7fsn_ti														biological_process											owl:Class	
GO:0051376	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034052	biolink:NamedThing	positive regulation of plant-type hypersensitive response	Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.	got7fsn_ti	up-regulation of plant-type hypersensitive response|stimulation of plant-type hypersensitive response|up regulation of plant-type hypersensitive response|positive regulation of HR|upregulation of plant-type hypersensitive response|positive regulation of HR-PCD|activation of plant-type hypersensitive response|positive regulation of plant hypersensitive response													biological_process											owl:Class	
CHEBI:25185	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903670	biolink:NamedThing	regulation of sprouting angiogenesis	Any process that modulates the frequency, rate or extent of sprouting angiogenesis.	got7fsn_ti							pga	2014-11-27T10:10:51Z						biological_process											owl:Class	
GO:0120245	biolink:NamedThing	terminal acetylenic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.	got7fsn_ti	terminal alkyne substituted compound catabolic process|terminal alkyne substituted compound catabolism|terminal alkyne substituted compound breakdown|terminal alkyne substituted compound degradation	https://github.com/geneontology/go-ontology/issues/19842					krc	2020-08-17T22:48:58Z						biological_process											owl:Class	
CHEBI:29699	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902808	biolink:NamedThing	positive regulation of cell cycle G1/S phase transition	Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.	got7fsn_ti	up-regulation of cell cycle G1/S phase transition|up regulation of cell cycle G1/S phase transition|activation of cell cycle G1/S phase transition|upregulation of cell cycle G1/S phase transition						jl	2014-03-26T16:36:32Z						biological_process											owl:Class	
GO:0010113	biolink:NamedThing	negative regulation of systemic acquired resistance	Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance.	got7fsn_ti	downregulation of systemic acquired resistance|down-regulation of systemic acquired resistance|down regulation of systemic acquired resistance|inhibition of systemic acquired resistance													biological_process											owl:Class	
GO:0019455	biolink:NamedThing	L-cysteine catabolic process via cystine, using cystine reductase	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6).	got7fsn_ti	L-cysteine degradation via cystine, using cystine reductase|L-cysteine breakdown via cystine, using cystine reductase													biological_process											owl:Class	
GO:0043461	biolink:NamedThing	proton-transporting ATP synthase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.	got7fsn_ti	F-type ATPase complex assembly													biological_process											owl:Class	
GO:2000528	biolink:NamedThing	negative regulation of myeloid dendritic cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis.	got7fsn_ti							ebc	2011-03-23T12:18:39Z						biological_process											owl:Class	
GO:0019547	biolink:NamedThing	arginine catabolic process to ornithine	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine.	got7fsn_ti	arginine degradation to ornithine|arginine breakdown to ornithine													biological_process											owl:Class	
GO:0002819	biolink:NamedThing	regulation of adaptive immune response	Any process that modulates the frequency, rate, or extent of an adaptive immune response.	got7fsn_ti														biological_process											owl:Class	
PR:000011166	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901069	biolink:NamedThing	guanosine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines).	got7fsn_ti	guanosines breakdown|guanosines degradation|guanosine-containing compound catabolism|guanosines catabolic process|guanosines catabolism|guanosine-containing compound breakdown|guanosine-containing compound degradation						bf	2012-07-02T01:52:00Z						biological_process											owl:Class	
CHEBI:58432	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043902	biolink:NamedThing	obsolete positive regulation of multi-organism process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.	got7fsn_ti					This term was obsoleted because it is an unnecessary grouping term.					True				biological_process											owl:Class	
GO:1902661	biolink:NamedThing	positive regulation of glucose mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway.	got7fsn_ti	upregulation of glucose mediated signaling pathway|up regulation of glucose mediated signalling|activation of glucose mediated signaling pathway|up-regulation of glucose mediated signaling pathway|activation of glucose mediated signalling|positive regulation of glucose mediated signalling|up-regulation of glucose mediated signalling|up regulation of glucose mediated signaling pathway|upregulation of glucose mediated signalling						di	2014-01-28T17:54:47Z						biological_process											owl:Class	
GO:0098658	biolink:NamedThing	inorganic anion import across plasma membrane	The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	inorganic anion import into cell													biological_process											owl:Class	
CHEBI:45863	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001168	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase I upstream control element sequence-specific binding	OBSOLETE. Binding to a upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I.	got7fsn_ti	RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/15787			This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2011-02-03T04:10:23Z		True				molecular_function											owl:Class	
GO:0010877	biolink:NamedThing	lipid transport involved in lipid storage	The directed movement of lipids into cells that is part of their accumulation and maintenance.	got7fsn_ti														biological_process											owl:Class	
GO:0052049	biolink:NamedThing	obsolete interaction with host via protein secreted by type III secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type III secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:0048329	biolink:NamedThing	negative regulation of axial mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification.	got7fsn_ti	down-regulation of axial mesodermal cell fate specification|down regulation of axial mesodermal cell fate specification|downregulation of axial mesodermal cell fate specification|inhibition of axial mesodermal cell fate specification													biological_process											owl:Class	
GO:2000515	biolink:NamedThing	negative regulation of CD4-positive, alpha-beta T cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.	got7fsn_ti							ebc	2011-03-22T10:37:02Z						biological_process											owl:Class	
GO:0001528	biolink:NamedThing	obsolete elastin	OBSOLETE. A major structural protein of mammalian connective tissues; composed of one third glycine, and also rich in proline, alanine, and valine. Chains are cross-linked together via lysine residues.	got7fsn_ti	elastin			GO:0030023	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0015745	biolink:NamedThing	tartrate transmembrane transport	The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other.	got7fsn_ti	tartrate transport													biological_process											owl:Class	
GO:0015309	biolink:NamedThing	cycloheximide:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out).	got7fsn_ti	cycloheximide:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0046831	biolink:NamedThing	regulation of RNA export from nucleus	Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.	got7fsn_ti	regulation of RNA export from cell nucleus|regulation of RNA export out of nucleus|regulation of RNA transport from nucleus to cytoplasm|regulation of RNA-nucleus export													biological_process											owl:Class	
CHEBI:73693	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990517	biolink:NamedThing	obsolete protein localization to photoreceptor outer segment	OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment, which is a portion of a modified sensory cilium.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		krc	2014-10-14T14:01:34Z		True				biological_process											owl:Class	
GO:0032062	biolink:NamedThing	positive regulation of translation in response to osmotic stress	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti	upregulation of translation in response to osmotic stress|stimulation of translation in response to osmotic stress|up-regulation of translation in response to osmotic stress|up regulation of translation in response to osmotic stress|activation of translation in response to osmotic stress													biological_process											owl:Class	
GO:2000815	biolink:NamedThing	regulation of mRNA stability involved in response to oxidative stress	A process of regulation of mRNA stability that is involved in a response to oxidative stress.	got7fsn_ti							mah	2011-07-11T04:40:56Z						biological_process											owl:Class	
GO:2000765	biolink:NamedThing	regulation of cytoplasmic translation	Any process that modulates the frequency, rate or extent of cytoplasmic translation.	got7fsn_ti							vw	2011-06-20T10:39:19Z						biological_process											owl:Class	
GO:0106064	biolink:NamedThing	regulation of cobalamin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	got7fsn_ti							hjd	2017-10-27T17:33:05Z						biological_process											owl:Class	
GO:0034014	biolink:NamedThing	response to triglyceride	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.	got7fsn_ti	response to triacylglycerol|response to triacylglyceride													biological_process											owl:Class	
PR:000001212	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:443725	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29032	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070606	biolink:NamedThing	regulation of (1->3)-alpha-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.	got7fsn_ti	regulation of 1,3-alpha-glucan anabolism|regulation of 1,3-alpha-glucan synthesis|regulation of 1,3-alpha-glucan formation|regulation of alpha-1,3 glucan biosynthetic process|regulation of alpha-1,3 glucan synthesis|regulation of alpha-1,3 glucan biosynthesis|regulation of alpha-1,3 glucan anabolism|regulation of 1,3-alpha-glucan biosynthetic process|regulation of 1,3-alpha-glucan biosynthesis|regulation of alpha-1,3 glucan formation						mah	2009-04-29T01:22:45Z						biological_process											owl:Class	
GO:0052412	biolink:NamedThing	obsolete metabolism by host of symbiont cell wall pectin	OBSOLETE. The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because there is no evidence it exists.					True				biological_process											owl:Class	
UBERON:0004207	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004209	biolink:NamedThing	obsolete caspase-6 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	caspase-6 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1904459	biolink:NamedThing	negative regulation of substance P secretion	Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion.	got7fsn_ti	inhibition of substance P secretion|down-regulation of substance P secretion|downregulation of substance P secretion|down regulation of substance P secretion						sl	2015-07-09T19:32:57Z						biological_process											owl:Class	
GO:0004868	biolink:NamedThing	obsolete serpin	OBSOLETE. A superfamily of proteins, many of which inhibit serine proteinases and exhibit a high degree of homology with classical serine proteinase inhibitors such as alpha1-antitrypsin or antithrombin.	got7fsn_ti	serpin				This term was made obsolete because it represents a class of gene products.	GO:0004867				True				molecular_function											owl:Class	
GO:0075269	biolink:NamedThing	positive regulation of aecium development	Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.	got7fsn_ti														biological_process											owl:Class	
GO:0030568	biolink:NamedThing	obsolete plasmin inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase plasmin.	got7fsn_ti	plasmin inhibitor activity			GO:0004867	This term was made obsolete because it represents a regulator of an obsolete molecular function.					True				molecular_function											owl:Class	
GO:1990897	biolink:NamedThing	obsolete CTDK-1 complex	OBSOLETE. A protein complex that phosphorylates serine 2 residues in the CTD domain of productively elongating large subunits of DNA-directed RNA polymerase II, holoenzyme. In S. cerevisiae this complex consists of CTK1/CTK2/CTK3, in S. pombe Lsk1/Lsc1/Lsg1. Human CTK1 homologs include CDK12/13.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-11-06T01:57:32Z		True				cellular_component											owl:Class	
GO:0016865	biolink:NamedThing	obsolete intramolecular oxidoreductase activity, other intramolecular oxidoreductases	OBSOLETE. A grouping term for intramolecular oxidoreductases that cannot be more accurately categorized.	got7fsn_ti	intramolecular isomerase activity, other intramolecular oxidoreductases|intramolecular oxidoreductase activity, other intramolecular oxidoreductases				This term was made obsolete because it was an unnecessary grouping term.	GO:0016860				True				molecular_function											owl:Class	
GO:0048661	biolink:NamedThing	positive regulation of smooth muscle cell proliferation	Any process that activates or increases the rate or extent of smooth muscle cell proliferation.	got7fsn_ti	activation of smooth muscle cell proliferation|up regulation of smooth muscle cell proliferation|up-regulation of smooth muscle cell proliferation|positive regulation of SMC proliferation|upregulation of smooth muscle cell proliferation|stimulation of smooth muscle cell proliferation													biological_process											owl:Class	
CHEBI:62501	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005734	biolink:NamedThing	obsolete box C + D snoRNP protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	box C + D snoRNP protein				This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
GO:0046446	biolink:NamedThing	purine alkaloid metabolic process	The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.	got7fsn_ti	purine alkaloid metabolism													biological_process											owl:Class	
GO:0045149	biolink:NamedThing	acetoin metabolic process	The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source.	got7fsn_ti	acetoin metabolism													biological_process											owl:Class	
GO:0008507	biolink:NamedThing	sodium:iodide symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in).	got7fsn_ti	sodium/iodide symporter activity											Reactome:R-HSA-5658195|Reactome:R-HSA-429591		molecular_function											owl:Class	
GO:2001125	biolink:NamedThing	negative regulation of translational frameshifting	Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting.	got7fsn_ti							dph	2011-10-12T05:52:27Z						biological_process											owl:Class	
UBERON:0006965	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000733	biolink:NamedThing	regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.	got7fsn_ti	regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|regulation of GDNF receptor signaling pathway of ureteric bud formation						yaf	2011-06-13T11:14:40Z						biological_process											owl:Class	
GO:0051967	biolink:NamedThing	negative regulation of synaptic transmission, glutamatergic	Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.	got7fsn_ti	inhibition of synaptic transmission, glutamatergic|down-regulation of synaptic transmission, glutamatergic|downregulation of synaptic transmission, glutamatergic|down regulation of synaptic transmission, glutamatergic													biological_process											owl:Class	
GO:0045306	biolink:NamedThing	obsolete inhibitor of the establishment of competence for transformation activity	OBSOLETE. Inhibits the establishment of competence for transformation.	got7fsn_ti	inhibitor of the establishment of competence for transformation activity			GO:0045808	This term was made obsolete because it does not represent a true function.					True				molecular_function											owl:Class	
GO:1900341	biolink:NamedThing	positive regulation of methane biosynthetic process from formic acid	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from formic acid.	got7fsn_ti	up regulation of methane biosynthetic process from formic acid|upregulation of methane biosynthetic process from formic acid|activation of methane biosynthetic process from formic acid|up-regulation of methane biosynthetic process from formic acid						tt	2012-04-06T02:05:11Z						biological_process											owl:Class	
CL:0000891	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001195	biolink:NamedThing	negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.	got7fsn_ti	negative regulation of lysine biosynthetic process via aminoadipic acid and saccharopine|negative regulation of lysine biosynthesis via aminoadipic acid and saccharopine						mcc	2011-11-03T07:57:18Z						biological_process											owl:Class	
GO:0150072	biolink:NamedThing	positive regulation of arginase activity	Any process that activates or increases the frequency, rate or extent of arginase activity.	got7fsn_ti							bc	2018-07-25T09:26:20Z						biological_process											owl:Class	
GO:2001214	biolink:NamedThing	positive regulation of vasculogenesis	Any process that activates or increases the frequency, rate or extent of vasculogenesis.	got7fsn_ti	positive regulation of vascular morphogenesis						yaf	2011-11-15T01:22:39Z						biological_process											owl:Class	
CHEBI:30245	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042459	biolink:NamedThing	octopine catabolic process to proline	The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline.	got7fsn_ti	octopine breakdown to proline|octopine degradation to proline											MetaCyc:OCTOPINEDEG-PWY		biological_process											owl:Class	
GO:1900545	biolink:NamedThing	obsolete regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of phenotypic switching.	got7fsn_ti	regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		di	2012-05-14T11:28:41Z		True				biological_process											owl:Class	
GO:0000504	biolink:NamedThing	obsolete proteasome regulatory particle (sensu Bacteria)	OBSOLETE. A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).	got7fsn_ti	proteasome regulatory particle (sensu Bacteria)|26S proteasome				This term was made obsolete because there is no ubiquitin in bacteria and they do not have proteasome regulatory particles. Instead they have proteasome-activating nucleotidase.					True				cellular_component											owl:Class	
GO:0030066	biolink:NamedThing	obsolete cytochrome b6	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytochrome b-563|cytochrome b6			GO:0045158	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:25698	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904062	biolink:NamedThing	regulation of cation transmembrane transport	Any process that modulates the frequency, rate or extent of cation transmembrane transport.	got7fsn_ti							sl	2015-03-18T21:11:43Z						biological_process											owl:Class	
CHEBI:57289	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045096	biolink:NamedThing	obsolete acidic keratin	OBSOLETE. A type of intermediate filament.	got7fsn_ti	acidic keratin|type I intermediate filament			GO:0045095	This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
CL:0000615	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090121	biolink:NamedThing	low-density lipoprotein particle disassembly involved in cholesterol transport	The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport.	got7fsn_ti							tb	2009-12-07T12:59:14Z						biological_process											owl:Class	
GO:0050800	biolink:NamedThing	obsolete hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement	OBSOLETE. Catalysis of the hydrolysis of GTP to directly drive the cellular or subcellular transport of a substance.	got7fsn_ti	hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement				This term was made obsolete because it represents both process and function information.	GO:0003924|GO:0006810				True				molecular_function											owl:Class	
GO:2000014	biolink:NamedThing	regulation of endosperm development	Any process that modulates the frequency, rate or extent of endosperm development.	got7fsn_ti							tb	2010-08-05T11:22:21Z						biological_process											owl:Class	
GO:0015283	biolink:NamedThing	obsolete apoptogenic cytochrome c release channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	apoptogenic cytochrome c release channel activity|Bcl-2				This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0009858	biolink:NamedThing	obsolete compatible pollen-pistil interaction	OBSOLETE. An interaction between a pollen grain and pistil that results in unimpeded growth of the pollen tube through the stigma and style.	got7fsn_ti	compatible pollen-pistil interaction				This term was made obsolete because it represents a phenotype.					True				biological_process											owl:Class	
GO:0045653	biolink:NamedThing	negative regulation of megakaryocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.	got7fsn_ti	down-regulation of megakaryocyte differentiation|downregulation of megakaryocyte differentiation|inhibition of megakaryocyte differentiation|down regulation of megakaryocyte differentiation													biological_process											owl:Class	
GO:0003812	biolink:NamedThing	obsolete alternative-complement-pathway C3/C5 convertase activity	OBSOLETE. Catalysis of the cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg bond in complement component C5 alpha-chain to yield C5a and C5b.	got7fsn_ti	alternative-complement-pathway C3/C5 convertase activity|alternative complement pathway C3(C5) convertase activity|cobra venom factor-dependent C3 convertase|C5 convertase activity|complement C 3(C 5) convertase (amplification)|C3 convertase activity|C3b,Bb,CVF,Bb,C5 convertase activity|complement component C3/C5 convertase (alternative) activity|complement factor B activity|C3 proactivator|CVF,Bb|(C3b)n,Bb|proenzyme factor B|glycine-rich beta-glycoprotein|(CVF)-dependent glycine-rich-beta-glucoprotein|properdin factor B activity|heat-labile factor			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0034114	biolink:NamedThing	regulation of heterotypic cell-cell adhesion	Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion.	got7fsn_ti														biological_process											owl:Class	
GO:0045541	biolink:NamedThing	negative regulation of cholesterol biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.	got7fsn_ti	negative regulation of cholesterol formation|negative regulation of cholesterol biosynthesis|negative regulation of cholesterol synthesis|negative regulation of cholesterol anabolism|inhibition of cholesterol biosynthetic process|down-regulation of cholesterol biosynthetic process|downregulation of cholesterol biosynthetic process|down regulation of cholesterol biosynthetic process													biological_process											owl:Class	
GO:0015890	biolink:NamedThing	nicotinamide mononucleotide transport	The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP.	got7fsn_ti	nicotinamide ribonucleotide transport													biological_process											owl:Class	
GO:1900636	biolink:NamedThing	heptadecane biosynthetic process	The chemical reactions and pathways resulting in the formation of heptadecane.	got7fsn_ti	heptadecane formation|heptadecane anabolism|heptadecane synthesis|heptadecane biosynthesis						tt	2012-05-21T07:05:21Z						biological_process											owl:Class	
GO:0015961	biolink:NamedThing	diadenosine polyphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.	got7fsn_ti	diadenosine polyphosphate catabolism|diadenosine polyphosphate breakdown|diadenosine polyphosphate degradation													biological_process											owl:Class	
GO:1905801	biolink:NamedThing	positive regulation of intraciliary retrograde transport	Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport.	got7fsn_ti	upregulation of intraciliary retrograde transport|up-regulation of intraflagellar retrograde transport|activation of intraflagellar retrograde transport|up regulation of intraflagellar retrograde transport|positive regulation of intraflagellar retrograde transport|up regulation of intraciliary retrograde transport|activation of intraciliary retrograde transport|up-regulation of intraciliary retrograde transport|upregulation of intraflagellar retrograde transport						hbye	2017-01-11T12:58:35Z						biological_process											owl:Class	
GO:0033143	biolink:NamedThing	regulation of intracellular steroid hormone receptor signaling pathway	Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.	got7fsn_ti	regulation of steroid hormone receptor signaling pathway|regulation of steroid hormone receptor signalling pathway													biological_process											owl:Class	
CHEBI:59573	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120233	biolink:NamedThing	prenyl-FMNH2 binding	Binding to prenyl-FMNH2, a flavin mononucleotide obtained by prenylation of the N-10 position of FMNH2 followed by cyclisation. An essential cofactor for the decarboxylase enzymes UbiD and Fdc1.	got7fsn_ti	prenylated FMNH2 binding	https://github.com/geneontology/go-ontology/issues/19244					krc	2020-06-30T19:32:01Z						molecular_function											owl:Class	
GO:0045411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070366	biolink:NamedThing	regulation of hepatocyte differentiation	Any process that modulates the frequency, rate or extent of hepatocyte differentiation.	got7fsn_ti	regulation of liver cell differentiation													biological_process											owl:Class	
GO:2000151	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.	got7fsn_ti							dph	2010-10-01T07:11:15Z						biological_process											owl:Class	
GO:1903154	biolink:NamedThing	obsolete glucose transmembrane transporter activity involved in glucose import into cell	OBSOLETE. Any glucose transmembrane transporter activity that is involved in glucose import into cell.	got7fsn_ti	lactose/glucose efflux transporter activity involved in glucose import into cell|glucose transmembrane transporter activity involved in glucose import into cell|galactose/glucose (methylgalactoside) porter activity involved in glucose import into cell|glucose permease activity involved in glucose import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:59Z		True				molecular_function											owl:Class	
CHEBI:49713	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52971	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090579	biolink:NamedThing	obsolete dsDNA loop formation	OBSOLETE. The formation and maintenance of DNA loops that juxtapose separated regions on the same dsDNA molecule.	got7fsn_ti	chromatin looping|dsDNA looping	https://github.com/geneontology/go-ontology/issues/20204			This term was obsoleted because it was defined like a molecular function.	GO:0140587	tb	2014-05-12T14:45:58Z		True				biological_process											owl:Class	
GO:1901869	biolink:NamedThing	ecgonine methyl ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ecgonine methyl ester.	got7fsn_ti	ecgonine methyl ester synthesis|ecgonine methyl ester anabolism|ecgonine methyl ester biosynthesis|ecgonine methyl ester formation						ms	2013-02-04T11:58:25Z						biological_process											owl:Class	
CHEBI:51356	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008205	biolink:NamedThing	ecdysone metabolic process	The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development.	got7fsn_ti	ecdysone metabolism													biological_process											owl:Class	
GO:1900020	biolink:NamedThing	positive regulation of protein kinase C activity	Any process that activates or increases the frequency, rate or extent of protein kinase C activity.	got7fsn_ti	positive regulation of PKC|up regulation of PKC|positive regulation of PKC activity|up regulation of PKC activity						bf	2012-01-11T03:50:55Z						biological_process											owl:Class	
GO:1900882	biolink:NamedThing	17-methylnonadec-1-ene metabolic process	The chemical reactions and pathways involving 17-methylnonadec-1-ene.	got7fsn_ti	17-methylnonadec-1-ene metabolism						tt	2012-06-13T02:35:37Z						biological_process											owl:Class	
GO:0034100	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060597	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in mammary gland formation	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0060592|GO:0006357|GO:0030879	dph	2009-05-13T12:04:53Z		True				biological_process											owl:Class	
GO:0032694	biolink:NamedThing	negative regulation of interleukin-11 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production.	got7fsn_ti	negative regulation of IL-11 production|down regulation of interleukin-11 production|downregulation of interleukin-11 production|negative regulation of interleukin-11 biosynthetic process|inhibition of interleukin-11 production|negative regulation of interleukin-11 secretion|down-regulation of interleukin-11 production										GO:0045364|GO:0150170			biological_process											owl:Class	
GO:1905292	biolink:NamedThing	regulation of neural crest cell differentiation	Any process that modulates the frequency, rate or extent of neural crest cell differentiation.	got7fsn_ti							rl	2016-06-28T15:02:01Z						biological_process											owl:Class	
GO:0000961	biolink:NamedThing	negative regulation of mitochondrial RNA catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.	got7fsn_ti														biological_process											owl:Class	
GO:0051096	biolink:NamedThing	positive regulation of helicase activity	Any process that activates or increases the activity of a helicase.	got7fsn_ti	activation of helicase activity|stimulation of helicase activity|upregulation of helicase activity|up regulation of helicase activity|up-regulation of helicase activity													biological_process											owl:Class	
GO:2000602	biolink:NamedThing	obsolete regulation of interphase of mitotic cell cycle	OBSOLETE. Any process that modulates the frequency, rate or extent of interphase of mitotic cell cycle.	got7fsn_ti	regulation of interphase of mitotic cell cycle				This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		pr	2011-04-15T03:52:25Z		True				biological_process											owl:Class	
GO:0014873	biolink:NamedThing	response to muscle activity involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation.	got7fsn_ti	response to fatigue|response to muscle activity involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0070101	biolink:NamedThing	positive regulation of chemokine-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.	got7fsn_ti	positive regulation of chemokine-mediated signalling pathway													biological_process											owl:Class	
GO:0022867	biolink:NamedThing	obsolete transmembrane 2-electron transfer carrier	OBSOLETE. Enables transfer of two electrons across a membrane.	got7fsn_ti	transmembrane two-electron transfer carrier				The reason for obsoletion is that the term does not represent a molecular function but rather a process.					True				molecular_function											owl:Class	
GO:0046444	biolink:NamedThing	FMN metabolic process	The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.	got7fsn_ti	FMN metabolism													biological_process											owl:Class	
GO:0005650	biolink:NamedThing	obsolete importin, alpha-subunit transport factor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	importin, alpha-subunit transport factor|CAS				This term was made obsolete because it represents a single gene product and not a complex.	GO:0005737|GO:0005634|GO:0005643				True				cellular_component											owl:Class	
GO:0042634	biolink:NamedThing	regulation of hair cycle	Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.	got7fsn_ti														biological_process											owl:Class	
GO:1902245	biolink:NamedThing	cis-abienol catabolic process	The chemical reactions and pathways resulting in the breakdown of cis-abienol.	got7fsn_ti	cis-abienol degradation|cis-abienol breakdown|cis-abienol catabolism						ms	2013-06-20T09:09:57Z						biological_process											owl:Class	
CHEBI:27343	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005082	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37257	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051628	biolink:NamedThing	positive regulation of epinephrine uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.	got7fsn_ti	positive regulation of adrenaline uptake|upregulation of epinephrine uptake|stimulation of epinephrine uptake|up-regulation of epinephrine uptake|up regulation of epinephrine uptake|positive regulation of epinephrine import|activation of epinephrine uptake													biological_process											owl:Class	
GO:1902872	biolink:NamedThing	regulation of horizontal cell localization	Any process that modulates the frequency, rate or extent of horizontal cell localization.	got7fsn_ti	regulation of retinal horizontal cell positioning|regulation of horizontal cell positioning|regulation of horizontal cell localisation|regulation of laminar positioning of retinal horizontal cell						mr	2014-04-03T15:24:58Z						biological_process											owl:Class	
GO:1903228	biolink:NamedThing	xanthosine catabolic process	The chemical reactions and pathways resulting in the breakdown of xanthosine.	got7fsn_ti	xanthosine degradation|xanthosine breakdown|xanthosine catabolism						jl	2014-07-31T09:21:52Z						biological_process											owl:Class	
GO:0075265	biolink:NamedThing	positive regulation of oogonium development	Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.	got7fsn_ti														biological_process											owl:Class	
GO:0019868	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006666	biolink:NamedThing	3-keto-sphinganine metabolic process	The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.	got7fsn_ti	3-keto-dihydrosphingosine metabolic process|3-keto-sphinganine metabolism|3-keto-dihydrosphingosine metabolism													biological_process											owl:Class	
GO:0001610	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075181	biolink:NamedThing	obsolete positive regulation of symbiont transcription in response to host	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/22014			This term was obsoleted because it represents a GO-CAM model.	GO:0006355				True				biological_process											owl:Class	
GO:0046087	biolink:NamedThing	cytidine metabolic process	The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside.	got7fsn_ti	cytidine metabolism													biological_process											owl:Class	
GO:0009770	biolink:NamedThing	obsolete primary charge separation in photosystem I	OBSOLETE. Energized reaction-center P700 chlorophylls on photosystem I donate an electron to a loosely bound Quinone acceptor molecule X, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.	got7fsn_ti					This term was obsoleted because it represents a mechanism, and is outside the scope of GO.					True				biological_process											owl:Class	
GO:0035505	biolink:NamedThing	positive regulation of myosin light chain kinase activity	Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity.	got7fsn_ti							bf	2010-04-30T10:48:09Z						biological_process											owl:Class	
GO:0046209	biolink:NamedThing	nitric oxide metabolic process	The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	got7fsn_ti	nitric oxide metabolism													biological_process											owl:Class	
GO:0021882	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0021877				True				biological_process											owl:Class	
GO:0140466	biolink:NamedThing	iron-sulfur cluster export from the mitochondrion	The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19504					pg	2020-05-22T10:01:36Z						biological_process											owl:Class	
GO:1903322	biolink:NamedThing	positive regulation of protein modification by small protein conjugation or removal	Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal.	got7fsn_ti	upregulation of protein modification by small protein conjugation or removal|activation of protein modification by small protein conjugation or removal|up regulation of protein modification by small protein conjugation or removal|up-regulation of protein modification by small protein conjugation or removal						vw	2014-08-18T13:01:15Z						biological_process											owl:Class	
GO:1902131	biolink:NamedThing	(+)-lariciresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol.	got7fsn_ti	(+)-lariciresinol degradation|(+)-lariciresinol breakdown|(+)-lariciresinol catabolism						ms	2013-05-21T08:49:54Z						biological_process											owl:Class	
GO:1902685	biolink:NamedThing	positive regulation of receptor localization to synapse	Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.	got7fsn_ti	upregulation of receptor localization to synapse|up regulation of receptor localization to synapse|activation of receptor localisation to synapse|up-regulation of receptor localisation to synapse|upregulation of receptor localisation to synapse|up-regulation of receptor localization to synapse|positive regulation of receptor localisation to synapse|up regulation of receptor localisation to synapse|activation of receptor localization to synapse						kmv	2014-02-07T17:38:51Z						biological_process											owl:Class	
CHEBI:18504	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034147	biolink:NamedThing	regulation of toll-like receptor 5 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 5 signalling pathway|regulation of TLR5 signaling pathway													biological_process											owl:Class	
NCBITaxon:10090	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070811	biolink:NamedThing	glycerol-2-phosphate transmembrane transport	The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol.	got7fsn_ti	glycerol-2-phosphate transport						mah	2009-07-08T04:57:38Z						biological_process											owl:Class	
GO:0060162	biolink:NamedThing	negative regulation of phospholipase C-activating dopamine receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway.	got7fsn_ti	negative regulation of phospholipase C-activating dopamine receptor signalling pathway|negative regulation of dopamine receptor, phospholipase C activating pathway													biological_process											owl:Class	
GO:0052416	biolink:NamedThing	obsolete metabolism by host of symbiont macromolecule	OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
UBERON:0005102	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004628	biolink:NamedThing	obsolete calcium-independent cytosolic phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	got7fsn_ti	calcium-independent cytosolic phospholipase A2 activity				This term was made obsolete because it represents component and function information.	GO:0047499|GO:0005829				True				molecular_function											owl:Class	
GO:0032376	biolink:NamedThing	positive regulation of cholesterol transport	Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	up-regulation of cholesterol transport|stimulation of cholesterol transport|up regulation of cholesterol transport|upregulation of cholesterol transport|activation of cholesterol transport													biological_process											owl:Class	
GO:0002186	biolink:NamedThing	cytosolic creatine kinase complex	A dimeric protein complex having creatine kinase activity.	got7fsn_ti							hjd	2011-06-14T02:14:16Z						cellular_component											owl:Class	
GO:1900788	biolink:NamedThing	pseurotin A metabolic process	The chemical reactions and pathways involving pseurotin A.	got7fsn_ti	Pseurotin metabolism|Pseurotin metabolic process|pseurotin A metabolism						di	2012-06-04T09:37:18Z						biological_process											owl:Class	
GO:0009601	biolink:NamedThing	detection of insect	The series of events in which a stimulus from an insect is received and converted into a molecular signal.	got7fsn_ti	perception of insect													biological_process											owl:Class	
GO:0019489	biolink:NamedThing	methylgallate metabolic process	The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.	got7fsn_ti	methylgallate metabolism													biological_process											owl:Class	
GO:0071654	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 1 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.	got7fsn_ti	positive regulation of TCA-3 production|positive regulation of T cell activation 3 production|positive regulation of CCL1 production						mah	2010-02-12T10:41:14Z						biological_process											owl:Class	
GO:0000190	biolink:NamedThing	obsolete MAPKKK cascade (pseudohyphal growth)	OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth.	got7fsn_ti	MAPKKK cascade (pseudohyphal growth)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0100009	biolink:NamedThing	regulation of fever generation by prostaglandin secretion	Any prostaglandin secretion process that regulates fever generation.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
GO:1990057	biolink:NamedThing	obsolete cell cycle arrest in response to DNA damage stimulus	OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of DNA damage from environmental insults or errors during metabolism.	got7fsn_ti	cell cycle arrest in response to DNA damage stimulus				This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2013-03-06T13:48:44Z		True				biological_process											owl:Class	
PO:0025082	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0106109	biolink:NamedThing	positive regulation of (R)-mevalonic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.	got7fsn_ti							hjd	2018-03-27T14:20:47Z						biological_process											owl:Class	
GO:0010875	biolink:NamedThing	positive regulation of cholesterol efflux	Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.	got7fsn_ti														biological_process											owl:Class	
GO:1905315	biolink:NamedThing	cell proliferation involved in endocardial cushion morphogenesis	Any cell proliferation that is involved in endocardial cushion morphogenesis.	got7fsn_ti							rl	2016-07-12T13:56:36Z						biological_process											owl:Class	
GO:0032915	biolink:NamedThing	positive regulation of transforming growth factor beta2 production	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2.	got7fsn_ti	positive regulation of TGFB2 production|up-regulation of transforming growth factor-beta2 production|positive regulation of transforming growth factor-beta2 production|up regulation of transforming growth factor-beta2 production|upregulation of transforming growth factor-beta2 production|positive regulation of TGF-B2 production|stimulation of transforming growth factor-beta2 production|activation of transforming growth factor-beta2 production													biological_process											owl:Class	
GO:0033502	biolink:NamedThing	cellular galactose homeostasis	A cellular homeostatic process involved in the maintenance of an internal steady state of galactose within a cell or between a cell and its external environment.	got7fsn_ti	cell galactose homeostasis													biological_process											owl:Class	
GO:0045917	biolink:NamedThing	positive regulation of complement activation	Any process that activates or increases the frequency, rate or extent of complement activation.	got7fsn_ti	up regulation of complement activation|positive regulation of complement cascade|stimulation of complement activation|upregulation of complement activation|up-regulation of complement activation|activation of complement activation													biological_process											owl:Class	
GO:0010265	biolink:NamedThing	SCF complex assembly	The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.	got7fsn_ti														biological_process											owl:Class	
GO:0048023	biolink:NamedThing	positive regulation of melanin biosynthetic process	Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.	got7fsn_ti	positive regulation of melanin anabolism|up regulation of melanin biosynthetic process|stimulation of melanin biosynthetic process|positive regulation of melanin formation|positive regulation of melanin biosynthesis|up-regulation of melanin biosynthetic process|activation of melanin biosynthetic process|upregulation of melanin biosynthetic process|positive regulation of melanin synthesis													biological_process											owl:Class	
GO:0062127	biolink:NamedThing	fatty acid primary amide catabolic process	The chemical reactions and pathways resulting in the breakdown of primary fatty amides.	got7fsn_ti	primary fatty amide catabolic process						dph	2019-05-30T18:26:49Z						biological_process											owl:Class	
GO:0016488	biolink:NamedThing	farnesol catabolic process	The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.	got7fsn_ti	farnesol degradation|farnesol catabolism|farnesol breakdown													biological_process											owl:Class	
GO:0098696	biolink:NamedThing	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane.	got7fsn_ti							dos	2017-04-04T16:33:38Z						biological_process											owl:Class	
GO:0032901	biolink:NamedThing	positive regulation of neurotrophin production	Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin.	got7fsn_ti	upregulation of neurotrophin production|stimulation of neurotrophin production|up-regulation of neurotrophin production|up regulation of neurotrophin production|activation of neurotrophin production													biological_process											owl:Class	
GO:1904587	biolink:NamedThing	response to glycoprotein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.	got7fsn_ti	response to glycoproteins						sl	2015-08-20T16:46:24Z						biological_process											owl:Class	
GO:0010167	biolink:NamedThing	response to nitrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0071328	biolink:NamedThing	cellular response to maltose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.	got7fsn_ti							mah	2009-12-10T05:30:45Z						biological_process											owl:Class	
GO:0010712	biolink:NamedThing	regulation of collagen metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	got7fsn_ti	regulation of collagen metabolism													biological_process											owl:Class	
GO:0098902	biolink:NamedThing	regulation of membrane depolarization during action potential	Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential.	got7fsn_ti														biological_process											owl:Class	
GO:0070570	biolink:NamedThing	regulation of neuron projection regeneration	Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.	got7fsn_ti							mah	2009-04-15T01:23:48Z						biological_process											owl:Class	
GO:0070430	biolink:NamedThing	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.	got7fsn_ti	positive regulation of NOD1 signaling pathway|positive regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway													biological_process											owl:Class	
CHEBI:64747	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032688	biolink:NamedThing	negative regulation of interferon-beta production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.	got7fsn_ti	inhibition of interferon-beta production|negative regulation of interferon-beta secretion|negative regulation of IFN-beta production|down-regulation of interferon-beta production|negative regulation of interferon-beta biosynthetic process|down regulation of interferon-beta production|downregulation of interferon-beta production										GO:0035548|GO:0045358			biological_process											owl:Class	
GO:2000157	biolink:NamedThing	negative regulation of ubiquitin-specific protease activity	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.	got7fsn_ti	negative regulation of UBP|negative regulation of ubiquitin hydrolase activity|negative regulation of UCH2|negative regulation of deubiquitinase activity						tb	2010-10-04T10:42:27Z						biological_process											owl:Class	
GO:0034487	biolink:NamedThing	vacuolar amino acid transmembrane transport	The process in which an amino acid is transported from one side of the vacuolar membrane to the other.	got7fsn_ti	vacuolar amino acid membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.									biological_process											owl:Class	
GO:0045868	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052508	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	upregulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont SA-mediated signal transduction pathway|induction by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway|induction by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0015520	biolink:NamedThing	tetracycline:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out).	got7fsn_ti	tetracycline:hydrogen antiporter activity|tetracyclin:hydrogen antiporter activity|tetracyclin:proton antiporter activity													molecular_function											owl:Class	
GO:0010725	biolink:NamedThing	regulation of primitive erythrocyte differentiation	Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.	got7fsn_ti	regulation of primitive RBC differentiation|regulation of primitive red blood cell differentiation|regulation of primitive erythropoeisis													biological_process											owl:Class	
GO:0008018	biolink:NamedThing	obsolete structural protein of chorion (sensu Drosophila)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	structural protein of chorion (sensu Drosophila)			GO:0005213	This term was made obsolete because the function is covered by a parent term.					True				molecular_function											owl:Class	
CHEBI:61082	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005281	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904292	biolink:NamedThing	regulation of ERAD pathway	Any process that modulates the frequency, rate or extent of ERAD pathway.	got7fsn_ti	regulation of endoplasmic reticulum-associated protein degradation pathway|regulation of endoplasmic reticulum-associated degradation|regulation of ER-associated degradation pathway						bf	2015-06-09T14:44:27Z						biological_process											owl:Class	
GO:0035774	biolink:NamedThing	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.	got7fsn_ti	positive regulation of insulin secretion in response to glucose						bf	2011-04-01T01:49:09Z						biological_process											owl:Class	
GO:1902812	biolink:NamedThing	regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.	got7fsn_ti	regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry						mr	2014-03-26T21:18:44Z						biological_process											owl:Class	
GO:0046853	biolink:NamedThing	obsolete inositol or phosphatidylinositol phosphorylation	OBSOLETE. The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms.	got7fsn_ti	inositol and derivative phosphorylation|myo-inositol and derivative phosphorylation|inositol or phosphatidylinositol phosphorylation|myo-inositol or phosphatidyl-myo-inositol phosphorylation				This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.	GO:0052746|GO:0046854				True				biological_process											owl:Class	
CHEBI:17536	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009663	biolink:NamedThing	plasmodesma organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.	got7fsn_ti	plasmodesmata organization and biogenesis|plasmodesma organisation|plasmodesma organization and biogenesis													biological_process											owl:Class	
GO:0035275	biolink:NamedThing	dibutyl phthalate binding	Binding to dibutyl phthalate, C(16)H(22)O(4).	got7fsn_ti	phthalic acid dibutyl ester binding|DBP binding													molecular_function											owl:Class	
GO:1904053	biolink:NamedThing	positive regulation of protein targeting to vacuole involved in autophagy	Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy.	got7fsn_ti	upregulation of protein targeting to vacuole involved in autophagy|up regulation of protein targeting to vacuole involved in autophagy|activation of protein targeting to vacuole involved in autophagy|up-regulation of protein targeting to vacuole involved in autophagy				An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).		pad	2015-03-17T13:54:27Z						biological_process											owl:Class	
GO:1905591	biolink:NamedThing	regulation of optical nerve axon regeneration	Any process that modulates the frequency, rate or extent of optical nerve axon regeneration.	got7fsn_ti							pga	2016-10-25T12:58:43Z						biological_process											owl:Class	
CL:0000797	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032534	biolink:NamedThing	regulation of microvillus assembly	A process that modulates the formation of a microvillus.	got7fsn_ti	regulation of microvillus biogenesis													biological_process											owl:Class	
GO:0039015	biolink:NamedThing	cell proliferation involved in pronephros development	The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.	got7fsn_ti	cell proliferation involved in pronephric kidney development						bf	2010-07-02T10:01:49Z						biological_process											owl:Class	
GO:0098871	biolink:NamedThing	postsynaptic actin cytoskeleton	The actin cytoskeleton that is part of a postsynapse.	got7fsn_ti														cellular_component											owl:Class	
GO:1902763	biolink:NamedThing	negative regulation of embryonic skeletal joint development	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development.	got7fsn_ti	down regulation of embryonic skeletal joint development|downregulation of embryonic skeletal joint development|down-regulation of embryonic skeletal joint development|inhibition of embryonic skeletal joint development						mr	2014-03-07T17:46:07Z						biological_process											owl:Class	
CHEBI:25437	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070955	biolink:NamedThing	negative regulation of neutrophil mediated killing of symbiont cell	Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.	got7fsn_ti	down regulation of neutrophil mediated killing of symbiont cell|inhibition of neutrophil mediated killing of symbiont cell|downregulation of neutrophil mediated killing of symbiont cell|down-regulation of neutrophil mediated killing of symbiont cell						mah	2009-10-01T02:20:17Z						biological_process											owl:Class	
GO:0009209	biolink:NamedThing	pyrimidine ribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside triphosphate biosynthesis|pyrimidine ribonucleoside triphosphate formation|pyrimidine ribonucleoside triphosphate synthesis|pyrimidine ribonucleoside triphosphate anabolism													biological_process											owl:Class	
GO:1902652	biolink:NamedThing	secondary alcohol metabolic process	The chemical reactions and pathways involving secondary alcohol.	got7fsn_ti	secondary alcohol metabolism						tt	2014-01-22T10:14:52Z						biological_process											owl:Class	
GO:1902089	biolink:NamedThing	cell wall polysaccharide catabolic process involved in lateral root development	Any cell wall polysaccharide catabolic process that is involved in lateral root development.	got7fsn_ti	cell wall polysaccharide breakdown involved in lateral root development						tb	2013-04-26T18:34:53Z						biological_process											owl:Class	
GO:0010795	biolink:NamedThing	regulation of ubiquinone biosynthetic process	Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.	got7fsn_ti														biological_process											owl:Class	
GO:0007058	biolink:NamedThing	spindle assembly involved in female meiosis II	The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.	got7fsn_ti	female meiosis II spindle assembly													biological_process											owl:Class	
GO:0061416	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to salt stress	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12739			This term was obsoleted because it represents a GO-CAM model.	GO:0071472|GO:0006357	dph	2012-01-23T12:56:36Z		True				biological_process											owl:Class	
PR:000001221	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990056	biolink:NamedThing	obsolete protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process	OBSOLETE. Catalysis of the phosphorylation of an amino acid residue in a substrate protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP, thereby targeting the substrate to the proteasomal ubiquitin mediated protein catabolic process.	got7fsn_ti	protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process				This term was obsoleted at the TermGenie Gatekeeper stage.		rb	2013-02-26T21:28:08Z		True				molecular_function											owl:Class	
UBERON:0004126	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903945	biolink:NamedThing	positive regulation of hepatocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.	got7fsn_ti	up-regulation of hepatocyte apoptotic process|activation of hepatocyte apoptotic process|up regulation of hepatocyte apoptotic process|positive regulation of hepatocyte apoptosis|up regulation of hepatocyte apoptosis|upregulation of hepatocyte apoptosis|upregulation of hepatocyte apoptotic process|activation of hepatocyte apoptosis|up-regulation of hepatocyte apoptosis						sl	2015-02-19T12:54:59Z						biological_process											owl:Class	
GO:0004294	biolink:NamedThing	obsolete tripeptidyl-peptidase II activity	OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide at neutral pH.	got7fsn_ti	tripeptidyl aminopeptidase activity|tripeptidyl peptidase activity|tripeptidyl aminopeptidase II|tripeptidyl peptidase II|TPP|tripeptidyl-peptidase II activity			GO:0008240	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0046670	biolink:NamedThing	positive regulation of retinal cell programmed cell death	Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.	got7fsn_ti	up regulation of retinal programmed cell death|positive regulation of retinal programmed cell death|stimulation of retinal programmed cell death|upregulation of retinal programmed cell death|activation of retinal programmed cell death|up-regulation of retinal programmed cell death													biological_process											owl:Class	
GO:0010010	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052181	biolink:NamedThing	obsolete modulation by host of symbiont defense response	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response.					True				biological_process											owl:Class	
GO:1901074	biolink:NamedThing	regulation of engulfment of apoptotic cell	Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell.	got7fsn_ti	regulation of engulfment of apoptotic cell corpse|regulation of engulfment of cell corpse						kmv	2012-07-02T07:32:21Z						biological_process											owl:Class	
PR:000001096	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010856	biolink:NamedThing	adenylate cyclase activator activity	Increases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0019761	biolink:NamedThing	glucosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.	got7fsn_ti	glucosinolate biosynthesis|glucosinolate anabolism|glucosinolate formation|glucosinolate synthesis													biological_process											owl:Class	
GO:0010983	biolink:NamedThing	positive regulation of high-density lipoprotein particle clearance	Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							tb	2009-06-01T12:03:32Z						biological_process											owl:Class	
GO:1900995	biolink:NamedThing	ubiquinone-6 binding	Binding to ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.	got7fsn_ti							bf	2012-06-14T02:49:15Z						molecular_function											owl:Class	
GO:0071652	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 1 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.	got7fsn_ti	regulation of TCA-3 production|regulation of T cell activation 3 production|regulation of CCL1 production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:1902332	biolink:NamedThing	bacterial-type DNA replication DNA duplex unwinding	Any DNA duplex unwinding that is involved in bacterial-type DNA replication.	got7fsn_ti	DNA duplex unwinding involved in bacterial-type DNA replication|duplex DNA melting involved in bacterial-type DNA replication|DNA unwinding involved in bacterial-type DNA replication						jl	2013-07-25T10:48:34Z						biological_process											owl:Class	
CHEBI:62781	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009759	biolink:NamedThing	indole glucosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.	got7fsn_ti	indole glucosinolate formation|indole glucosinolate synthesis|indole glucosinolate anabolism|indole glucosinolate biosynthesis													biological_process											owl:Class	
GO:0150128	biolink:NamedThing	negative regulation of interleukin-33 production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production.	got7fsn_ti	negative regulation of interleukin-33 secretion|negative regulation of interleukin-33 biosynthetic process						bc	2019-12-03T05:54:24Z			GO:0150124|GO:0150131			biological_process											owl:Class	
CHEBI:62070	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010567	biolink:NamedThing	regulation of ketone catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.	got7fsn_ti														biological_process											owl:Class	
GO:0004242	biolink:NamedThing	obsolete beta-mitochondrial processing peptidase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	beta-mitochondrial processing peptidase|beta-MPP				This term was made obsolete because it represents a gene product.	GO:0005739|GO:0004222				True				molecular_function											owl:Class	
GO:0035443	biolink:NamedThing	tripeptide transmembrane transport	The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds.	got7fsn_ti	tripeptide membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-13T09:20:25Z						biological_process											owl:Class	
GO:0034650	biolink:NamedThing	cortisol metabolic process	The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.	got7fsn_ti	cortisol metabolism													biological_process											owl:Class	
GO:1990336	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032884	biolink:NamedThing	regulation of cell wall chitin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin.	got7fsn_ti	regulation of cell wall chitin anabolism|regulation of cell wall chitin synthesis|regulation of cell wall chitin formation|regulation of cell wall chitin biosynthesis													biological_process											owl:Class	
GO:0090621	biolink:NamedThing	obsolete APC-fizzy-related complex	OBSOLETE. An anaphase promoting complex bound to the fizzy-related family APC activator FZR1/Cdh1/Srw1 that regulates mitotic exit by activating the APC/C to target mitotic cyclins for destruction during anaphase and telophase. Is also active during G1.	got7fsn_ti	APC-Srw1 complex|APC-Hct1/Cdh1 complex				This term was made obsolete because it is too fine-grained for GO.	GO:0005680	tb	2014-12-17T17:01:38Z		True				cellular_component											owl:Class	
GO:0004010	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002836	biolink:NamedThing	positive regulation of response to tumor cell	Any process that activates or increases the frequency, rate, or extent of a response to tumor cell.	got7fsn_ti	up regulation of response to tumor cell|positive regulation of response to tumour cell|activation of response to tumor cell|stimulation of response to tumor cell|upregulation of response to tumor cell|up-regulation of response to tumor cell													biological_process											owl:Class	
GO:1900077	biolink:NamedThing	negative regulation of cellular response to insulin stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.	got7fsn_ti	down regulation of cellular response to insulin stimulus|downregulation of cellular response to insulin stimulus|inhibition of cellular response to insulin stimulus|down-regulation of cellular response to insulin stimulus						yaf	2012-01-31T11:23:15Z						biological_process											owl:Class	
GO:0009161	biolink:NamedThing	ribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	ribonucleoside monophosphate metabolism													biological_process											owl:Class	
CHEBI:23981	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052360	biolink:NamedThing	obsolete catabolism by host of symbiont macromolecule	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:1900235	biolink:NamedThing	negative regulation of Kit signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway.	got7fsn_ti	down regulation of Kit signaling pathway|down-regulation of stem cell factor signaling pathway|inhibition of Kit signaling pathway|negative regulation of stem cell factor signaling pathway|downregulation of stem cell factor signaling pathway|down-regulation of stem cell factor receptor signaling pathway|negative regulation of Kit signalling pathway|downregulation of stem cell factor receptor signaling pathway|down regulation of stem cell factor signaling pathway|negative regulation of stem cell factor receptor signaling pathway|downregulation of Kit signaling pathway|down regulation of stem cell factor receptor signaling pathway|down-regulation of Kit signaling pathway|inhibition of stem cell factor receptor signaling pathway|inhibition of stem cell factor signaling pathway						bf	2012-03-23T02:54:23Z						biological_process											owl:Class	
GO:0015331	biolink:NamedThing	obsolete asparagine/glutamine permease activity	OBSOLETE. Catalysis of the stereospecific transfer of asparagine or glutamine across a biological membrane.	got7fsn_ti	asparagine/glutamine permease activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0022857|GO:0015186|GO:0015182				True				molecular_function											owl:Class	
GO:0060755	biolink:NamedThing	negative regulation of mast cell chemotaxis	Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.	got7fsn_ti							dph	2009-06-22T02:40:58Z						biological_process											owl:Class	
GO:0075184	biolink:NamedThing	regulation of infection cushion formation	Any process that modulates the frequency, rate or extent of symbiont infection cushion formation.	got7fsn_ti	regulation of infection cushion formation on or near host													biological_process											owl:Class	
GO:1901437	biolink:NamedThing	regulation of toluene metabolic process	Any process that modulates the frequency, rate or extent of toluene metabolic process.	got7fsn_ti	regulation of methylbenzene metabolism|regulation of methylbenzene metabolic process|regulation of toluene metabolism						tt	2012-10-01T21:17:41Z						biological_process											owl:Class	
CL:1001569	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009377	biolink:NamedThing	obsolete HslUV protease activity	OBSOLETE. Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins.	got7fsn_ti	HslUV protease activity			GO:0008233	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
OBO:OBA_0000023	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000451	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta T cell extravasation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.	got7fsn_ti							bf	2011-03-04T10:42:14Z						biological_process											owl:Class	
GO:0005555	biolink:NamedThing	obsolete blood group antigen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	blood group antigen				This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True				molecular_function											owl:Class	
GO:0070174	biolink:NamedThing	negative regulation of enamel mineralization	Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.	got7fsn_ti														biological_process											owl:Class	
GO:0003754	biolink:NamedThing	obsolete chaperone activity	OBSOLETE. Assists in the correct non-covalent assembly of polypeptide-containing structures in vivo, but is not a component of these assembled structures when they are performing their normal biological function.	got7fsn_ti	chaperone activity				This term was made obsolete because, as defined, it represents a class of gene products rather than a molecular function. The term string is also ambiguous, having connotations of involvement in transport processes.	GO:0006457|GO:0044183|GO:0051082				True	GO:0003758|GO:0003757|GO:0003761|GO:0003760			molecular_function											owl:Class	
GO:0061940	biolink:NamedThing	regulation of c-di-GMP signaling	Any process that modulates the rate frequency or extent of c-di-GMP signaling.	got7fsn_ti							dph	2017-09-14T19:07:41Z						biological_process											owl:Class	
GO:0070540	biolink:NamedThing	stearic acid binding	Binding to stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0003402	biolink:NamedThing	planar cell polarity pathway involved in axis elongation	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation.	got7fsn_ti							dph	2009-12-21T01:22:11Z						biological_process											owl:Class	
GO:0033866	biolink:NamedThing	nucleoside bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	nucleoside bisphosphate anabolism|nucleoside bisphosphate formation|nucleoside bisphosphatehate synthesis|nucleoside bisphosphate biosynthesis													biological_process											owl:Class	
GO:1903659	biolink:NamedThing	regulation of complement-dependent cytotoxicity	Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity.	got7fsn_ti							jl	2014-11-25T15:03:54Z						biological_process											owl:Class	
GO:0006102	biolink:NamedThing	isocitrate metabolic process	The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.	got7fsn_ti	isocitrate metabolism													biological_process											owl:Class	
UBERON:0005515	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000545	biolink:NamedThing	negative regulation of endothelial cell chemotaxis to fibroblast growth factor	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.	got7fsn_ti							ebc	2011-04-03T07:14:11Z						biological_process											owl:Class	
GO:0045012	biolink:NamedThing	obsolete MHC class II receptor activity	OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.	got7fsn_ti	major histocompatibility complex class II receptor|MHC class II receptor activity|class II major histocompatibility complex antigen				This term was made obsolete because it was defined ambiguously, and has therefore been used incorrectly in annotations. To update annotations of gene products that act as receptors for MHC class II protein complexes, use the molecular function term 'MHC class II receptor activity ; GO:0032395'; to update annotations of gene products which are components of MHC class II protein complexes, use the cellular component term 'MHC class II protein complex ; GO:0042613'.	GO:0032395|GO:0042613				True				molecular_function											owl:Class	
CHEBI:61402	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045304	biolink:NamedThing	regulation of establishment of competence for transformation	Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome.	got7fsn_ti	regulator of establishment of competence for transformation activity													biological_process											owl:Class	
GO:1901545	biolink:NamedThing	response to raffinose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.	got7fsn_ti							al	2012-10-26T14:32:23Z						biological_process											owl:Class	
GO:0032909	biolink:NamedThing	regulation of transforming growth factor beta2 production	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.	got7fsn_ti	regulation of TGF-B2 production|regulation of TGFB2 production|regulation of transforming growth factor-beta2 production													biological_process											owl:Class	
GO:1905312	biolink:NamedThing	positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.	got7fsn_ti	upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|activation of cardiac neural crest cell migration involved in outflow tract morphogenesis|up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis						rl	2016-07-11T17:34:43Z						biological_process											owl:Class	
GO:0019298	biolink:NamedThing	coenzyme B biosynthetic process	The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.	got7fsn_ti	coenzyme B biosynthesis|coenzyme B synthesis|coenzyme B anabolism|coenzyme B formation											MetaCyc:P241-PWY		biological_process											owl:Class	
GO:1903889	biolink:NamedThing	negative regulation of plant epidermal cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation.	got7fsn_ti	down-regulation of plant epidermal cell differentiation|inhibition of plant epidermal cell differentiation|downregulation of plant epidermal cell differentiation|down regulation of plant epidermal cell differentiation						tb	2015-02-06T22:29:52Z						biological_process											owl:Class	
GO:0046475	biolink:NamedThing	glycerophospholipid catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.	got7fsn_ti	glycerophospholipid breakdown|phosphoglyceride catabolism|glycerophospholipid degradation|glycerophospholipid catabolism|phosphoglyceride catabolic process													biological_process											owl:Class	
CHEBI:52640	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003411	biolink:NamedThing	cell motility involved in camera-type eye morphogenesis	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye.	got7fsn_ti							dph	2009-12-21T03:04:27Z						biological_process											owl:Class	
GO:0005508	biolink:NamedThing	obsolete copper/cadmium binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	copper/cadmium binding				This term was made obsolete because it represents a composite function.	GO:0046870|GO:0005507				True				molecular_function											owl:Class	
GO:1903842	biolink:NamedThing	response to arsenite ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.	got7fsn_ti							mr	2015-01-22T19:56:05Z						biological_process											owl:Class	
GO:0034742	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060724	biolink:NamedThing	coreceptor activity involved in epidermal growth factor receptor signaling pathway	Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway.	got7fsn_ti	coreceptor activity involved in epidermal growth factor receptor signalling pathway						dph	2009-06-12T01:06:08Z						molecular_function											owl:Class	
GO:0052219	biolink:NamedThing	obsolete negative energy taxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative energy taxis in environment of other organism during symbiotic interaction|negative energy taxis in response to environment of other organism				This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0017028	biolink:NamedThing	obsolete protein stabilization activity	OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds.	got7fsn_ti	protein stabilization activity			GO:0050821	This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:2001119	biolink:NamedThing	methanofuran metabolic process	The chemical reactions and pathways involving a methanofuran.	got7fsn_ti	methanofuran metabolism						jl	2011-10-11T12:34:08Z						biological_process											owl:Class	
GO:0035952	biolink:NamedThing	obsolete negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	negative regulation of oligopeptide transport by downregulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by down regulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by down-regulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by inhibition of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by negative regulation of transcription from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0034104	biolink:NamedThing	negative regulation of tissue remodeling	Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.	got7fsn_ti														biological_process											owl:Class	
GO:1904717	biolink:NamedThing	regulation of AMPA glutamate receptor clustering	Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering.	got7fsn_ti	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|regulation of AMPA receptor clustering						hjd	2015-10-07T19:32:11Z						biological_process											owl:Class	
GO:0052203	biolink:NamedThing	obsolete modulation of catalytic activity in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation of enzyme activity within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
UBERON:0004152	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3528	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000067	biolink:NamedThing	regulation of root morphogenesis	Any process that modulates the frequency, rate or extent of root morphogenesis.	got7fsn_ti							tb	2010-08-23T09:25:13Z						biological_process											owl:Class	
GO:1900109	biolink:NamedThing	regulation of histone H3-K9 dimethylation	Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation.	got7fsn_ti	regulation of histone lysine H3 K9 dimethylation|regulation of histone H3 K9 dimethylation						bf	2012-02-21T09:06:18Z						biological_process											owl:Class	
GO:0071504	biolink:NamedThing	cellular response to heparin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.	got7fsn_ti							mah	2009-12-18T03:34:38Z						biological_process											owl:Class	
GO:0120012	biolink:NamedThing	intermembrane sphingolipid transfer	The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12329					krc	2017-03-16T22:20:45Z						biological_process											owl:Class	
GO:1901773	biolink:NamedThing	lincomycin catabolic process	The chemical reactions and pathways resulting in the breakdown of lincomycin.	got7fsn_ti	lincomycin catabolism|lincomycin degradation|lincomycin breakdown						yaf	2013-01-15T11:53:57Z						biological_process											owl:Class	
GO:0002185	biolink:NamedThing	creatine kinase complex	A protein complex having creatine kinase activity.	got7fsn_ti							hjd	2011-06-14T02:12:19Z						cellular_component											owl:Class	
GO:0045757	biolink:NamedThing	obsolete negative regulation of actin polymerization and/or depolymerization	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization and/or depolymerization.	got7fsn_ti	negative regulation of actin polymerization and/or depolymerization				This term was made obsolete because it has been split.	GO:0030837|GO:0030835				True				biological_process											owl:Class	
GO:1904846	biolink:NamedThing	negative regulation of establishment of bipolar cell polarity	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity.	got7fsn_ti	down regulation of establishment of bipolar cell polarity|down-regulation of establishment of bipolar cell polarity|downregulation of establishment of bipolar cell polarity|inhibition of establishment of bipolar cell polarity						al	2015-12-08T15:06:30Z						biological_process											owl:Class	
GO:1904825	biolink:NamedThing	protein localization to microtubule plus-end	A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end.	got7fsn_ti	protein localisation to microtubule plus-end						mah	2015-11-23T12:34:09Z						biological_process											owl:Class	
GO:0046898	biolink:NamedThing	response to cycloheximide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.	got7fsn_ti	response to actidione													biological_process											owl:Class	
GO:0090134	biolink:NamedThing	cell migration involved in mesendoderm migration	The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue.	got7fsn_ti							tb	2009-12-07T03:28:11Z						biological_process											owl:Class	
GO:0007205	biolink:NamedThing	protein kinase C-activating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).	got7fsn_ti	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|activation of protein kinase C activity by G-protein coupled receptor protein signalling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway													biological_process											owl:Class	
GO:2000493	biolink:NamedThing	negative regulation of interleukin-18-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway.	got7fsn_ti	negative regulation of interleukin-18-mediated signalling pathway						pr	2011-03-16T02:00:12Z						biological_process											owl:Class	
OBO:GOCHE_50790	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034649	biolink:NamedThing	obsolete histone demethylase activity (H3-monomethyl-K4 specific)	OBSOLETE. Catalysis of the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein.	got7fsn_ti	histone demethylase activity (H3-K4-me1 specific)	https://github.com/geneontology/go-ontology/issues/21089			This term was obsoleted to align with RHEA and EC: this is a sub-reaction both in RHEA:60208 and EC:1.14.11.67.	GO:0034647|GO:0140682				True				molecular_function											owl:Class	
GO:0009485	biolink:NamedThing	obsolete cbb3-type cytochrome c oxidase	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.	got7fsn_ti	cbb3-type cytochrome c oxidase			GO:0004129	This term was made obsolete because it describes a class of gene products rather than a molecular function.					True				molecular_function											owl:Class	
GO:0004201	biolink:NamedThing	obsolete caspase-1 activity	OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.	got7fsn_ti	ICE|caspase-1 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:1905103	biolink:NamedThing	integral component of lysosomal membrane	The component of the lysosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to lysosomal membrane|integral component of lysosome membrane						bf	2016-04-04T10:29:16Z						cellular_component											owl:Class	
GO:0014042	biolink:NamedThing	positive regulation of neuron maturation	Any process that activates or increases the frequency, rate or extent of neuron maturation.	got7fsn_ti	up-regulation of neuron maturation|up regulation of neuron maturation|upregulation of neuron maturation|activation of neuron maturation|stimulation of neuron maturation													biological_process											owl:Class	
GO:0042413	biolink:NamedThing	carnitine catabolic process	The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	got7fsn_ti	vitamin Bt catabolism|carnitine degradation|carnitine catabolism|vitamin Bt catabolic process|carnitine breakdown													biological_process											owl:Class	
GO:0006064	biolink:NamedThing	glucuronate catabolic process	The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid.	got7fsn_ti	glucuronate catabolism|glucuronate degradation|glucuronate breakdown													biological_process											owl:Class	
GO:0031307	biolink:NamedThing	integral component of mitochondrial outer membrane	The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to mitochondrial outer membrane													cellular_component											owl:Class	
UBERON:0000956	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090107	biolink:NamedThing	regulation of high-density lipoprotein particle assembly	Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.	got7fsn_ti							tb	2009-11-25T10:50:18Z						biological_process											owl:Class	
GO:0019503	biolink:NamedThing	stachydrine biosynthetic process	The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.	got7fsn_ti	stachydrine formation|stachydrine synthesis|stachydrine anabolism|stachydrine biosynthesis													biological_process											owl:Class	
GO:0062043	biolink:NamedThing	positive regulation of cardiac epithelial to mesenchymal transition	Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	got7fsn_ti							dph	2018-05-10T18:15:54Z						biological_process											owl:Class	
CHEBI:65109	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35584	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905508	biolink:NamedThing	protein localization to microtubule organizing center	A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.	got7fsn_ti	protein localisation to microtubule organizing center|protein localisation in microtubule organizing center|protein localization in microtubule organizing center						mah	2016-09-28T12:32:16Z						biological_process											owl:Class	
GO:0009938	biolink:NamedThing	negative regulation of gibberellic acid mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity.	got7fsn_ti	down regulation of gibberellic acid mediated signaling|down-regulation of gibberellic acid mediated signaling|downregulation of gibberellic acid mediated signaling|negative regulation of gibberellic acid mediated signalling|inhibition of gibberellic acid mediated signaling													biological_process											owl:Class	
GO:0015428	biolink:NamedThing	obsolete type I protein secretor activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	type I protein secretor activity				This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True				molecular_function											owl:Class	
GO:0046050	biolink:NamedThing	UMP catabolic process	The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate.	got7fsn_ti	UMP catabolism|UMP degradation|UMP breakdown													biological_process											owl:Class	
GO:0051983	biolink:NamedThing	regulation of chromosome segregation	Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.	got7fsn_ti														biological_process											owl:Class	
GO:0014742	biolink:NamedThing	positive regulation of muscle hypertrophy	Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.	got7fsn_ti														biological_process											owl:Class	
GO:1903321	biolink:NamedThing	negative regulation of protein modification by small protein conjugation or removal	Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal.	got7fsn_ti	inhibition of protein modification by small protein conjugation or removal|downregulation of protein modification by small protein conjugation or removal|down regulation of protein modification by small protein conjugation or removal|down-regulation of protein modification by small protein conjugation or removal						vw	2014-08-18T13:01:08Z						biological_process											owl:Class	
GO:1990807	biolink:NamedThing	obsolete protein N-acetyltransferase activity	OBSOLETE. Catalysis of the transfer of an acetyl group to a nitrogen atom on the amino acid of a protein.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2015-07-20T15:19:23Z		True				molecular_function											owl:Class	
GO:0033500	biolink:NamedThing	carbohydrate homeostasis	A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0097606	biolink:NamedThing	obsolete positive regulation of nuclear envelope permeability	OBSOLETE. Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.	got7fsn_ti	positive regulation of nuclear membrane permeability				The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it.		pr	2014-05-14T15:43:06Z		True				biological_process											owl:Class	
GO:1901577	biolink:NamedThing	regulation of alkane biosynthetic process	Any process that modulates the frequency, rate or extent of alkane biosynthetic process.	got7fsn_ti	regulation of alkane formation|regulation of alkane synthesis|regulation of alkane anabolism|regulation of alkane biosynthesis						dhl	2012-11-05T21:54:06Z						biological_process											owl:Class	
GO:2000148	biolink:NamedThing	regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.	got7fsn_ti							dph	2010-10-01T07:09:49Z						biological_process											owl:Class	
CHEBI:25822	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052490	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000391	biolink:NamedThing	positive regulation of neutrophil extravasation	Any process that activates or increases the frequency, rate or extent of neutrophil extravasation.	got7fsn_ti							mah	2011-02-22T11:08:42Z						biological_process											owl:Class	
GO:1905858	biolink:NamedThing	regulation of heparan sulfate proteoglycan binding	Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding.	got7fsn_ti	regulation of heparin proteoglycan binding						bc	2017-01-23T14:25:10Z						biological_process											owl:Class	
GO:2001123	biolink:NamedThing	maltoheptaose catabolic process	The chemical reactions and pathways resulting in the breakdown of a maltoheptaose.	got7fsn_ti	maltoheptaose catabolism						jl	2011-10-11T02:41:29Z						biological_process											owl:Class	
GO:0007592	biolink:NamedThing	obsolete protein-based cuticle development	OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this is found in Caenorhabditis elegans.	got7fsn_ti	protein-based cuticle anabolism|protein-based cuticle biosynthetic process|protein-based cuticle formation|protein-based cuticle development|protein-based cuticle synthesis				This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0040002|GO:0040003				True				biological_process											owl:Class	
GO:1905838	biolink:NamedThing	regulation of telomeric D-loop disassembly	Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly.	got7fsn_ti							nc	2017-01-18T11:01:38Z						biological_process											owl:Class	
GO:0051175	biolink:NamedThing	negative regulation of sulfur metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.	got7fsn_ti	downregulation of sulfur metabolic process|inhibition of sulfur metabolic process|negative regulation of sulfur metabolism|down regulation of sulfur metabolic process|negative regulation of sulphur metabolic process|down-regulation of sulfur metabolic process|negative regulation of sulphur metabolism													biological_process											owl:Class	
GO:0016121	biolink:NamedThing	carotene catabolic process	The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids.	got7fsn_ti	carotene catabolism|carotene degradation|carotene breakdown													biological_process											owl:Class	
GO:0014068	biolink:NamedThing	positive regulation of phosphatidylinositol 3-kinase signaling	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.	got7fsn_ti	stimulation of phosphatidylinositol 3-kinase cascade|positive regulation of PI 3-kinase cascade|activation of phosphoinositide 3-kinase cascade|positive regulation of PI3K cascade|up regulation of phosphatidylinositol 3-kinase cascade|positive regulation of phosphatidylinositol 3-kinase cascade|upregulation of phosphatidylinositol 3-kinase cascade|up-regulation of phosphatidylinositol 3-kinase cascade|positive regulation of phosphoinositide 3-kinase cascade													biological_process											owl:Class	
GO:1905110	biolink:NamedThing	negative regulation of pulmonary blood vessel remodeling	Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling.	got7fsn_ti	downregulation of pulmonary blood vessel remodeling|down-regulation of pulmonary blood vessel remodeling|inhibition of pulmonary blood vessel remodeling|down regulation of pulmonary blood vessel remodeling						bc	2016-04-06T13:07:33Z						biological_process											owl:Class	
CHEBI:11892	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904517	biolink:NamedThing	MgATP(2-) binding	Binding to MgATP(2-).	got7fsn_ti							bhm	2015-07-29T13:40:02Z						molecular_function											owl:Class	
GO:0072392	biolink:NamedThing	phenol catabolic process	The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.	got7fsn_ti							mah	2010-12-06T04:08:44Z						biological_process											owl:Class	
GO:0071874	biolink:NamedThing	cellular response to norepinephrine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.	got7fsn_ti	cellular response to noradrenaline stimulus				Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.		mah	2010-09-13T03:33:32Z						biological_process											owl:Class	
GO:0052133	biolink:NamedThing	obsolete positive aerotaxis in host	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive aerotaxis within host	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0070297	biolink:NamedThing	regulation of phosphorelay signal transduction system	Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.	got7fsn_ti	regulation of histidyl-aspartyl phosphorelay|regulation of two-component signal transduction system (phosphorelay)|regulation of two-component signal transduction system													biological_process											owl:Class	
GO:0031377	biolink:NamedThing	obsolete mitochondrial type II fatty acid synthase complex	OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the mitochondrion.	got7fsn_ti	mitochondrial type II fatty acid synthase complex|mitochondrial type II FAS complex				Obsoleted because type II fatty acid synthases are not complexes					True				cellular_component											owl:Class	
GO:0033585	biolink:NamedThing	L-phenylalanine biosynthetic process from chorismate via phenylpyruvate	The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate.	got7fsn_ti	L-phenylalanine formation from chorismate via phenylpyruvate|L-phenylalanine biosynthesis from chorismate via phenylpyruvate|L-phenylalanine synthesis from chorismate via phenylpyruvate|L-phenylalanine anabolism from chorismate via phenylpyruvate											MetaCyc:PHESYN		biological_process											owl:Class	
GO:0016171	biolink:NamedThing	obsolete cell surface antigen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cell surface antigen				This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True				molecular_function											owl:Class	
OIO:shorthand	biolink:NamedThing	shorthand		got7fsn_ti																									owl:AnnotationProperty	
GO:0008160	biolink:NamedThing	protein tyrosine phosphatase activator activity	Binds to and increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein.	got7fsn_ti														molecular_function											owl:Class	
GO:0000946	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033083	biolink:NamedThing	regulation of immature T cell proliferation	Any process that modulates the frequency, rate or extent of immature T cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0043272	biolink:NamedThing	ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance.	got7fsn_ti	ethylene synthesis during jasmonic acid and ethylene-dependent systemic resistance|ethylene biosynthetic process during jasmonic acid and ethylene-dependent systemic resistance|ethylene formation during jasmonic acid and ethylene-dependent systemic resistance|ethylene anabolism during jasmonic acid and ethylene-dependent systemic resistance													biological_process											owl:Class	
GO:0071935	biolink:NamedThing	octopamine signaling pathway involved in response to food	The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus.	got7fsn_ti	octopamine signalling pathway involved in response to food						mah	2010-09-30T11:55:59Z						biological_process											owl:Class	
GO:1902865	biolink:NamedThing	positive regulation of embryonic camera-type eye development	Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development.	got7fsn_ti	up-regulation of embryonic eye development|activation of embryonic camera-type eye development|upregulation of embryonic eye development|positive regulation of embryonic eye development|upregulation of embryonic camera-type eye development|up-regulation of embryonic camera-type eye development|activation of embryonic eye development|up regulation of embryonic camera-type eye development|up regulation of embryonic eye development						mr	2014-04-03T15:24:12Z						biological_process											owl:Class	
GO:0048780	biolink:NamedThing	positive regulation of erythrophore differentiation	Any process that activates or increases the frequency, rate or extent of erythrophore differentiation.	got7fsn_ti	up-regulation of erythrophore differentiation|up regulation of erythrophore differentiation|stimulation of erythrophore differentiation|upregulation of erythrophore differentiation|activation of erythrophore differentiation													biological_process											owl:Class	
GO:1903492	biolink:NamedThing	response to acetylsalicylate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.	got7fsn_ti							hp	2014-09-25T10:58:23Z						biological_process											owl:Class	
GO:1901350	biolink:NamedThing	obsolete cell-cell signaling involved in cell-cell junction organization	OBSOLETE. Any cell-cell signaling that is involved in cell-cell junction organization.	got7fsn_ti	cell-cell signaling involved in cell-cell junction organisation|cell-cell signaling involved in cell-cell junction assembly and maintenance|cell-cell signalling involved in cell-cell junction biogenesis|cell-cell signalling involved in cell-cell junction assembly and maintenance|cell-cell signaling involved in intercellular junction assembly and maintenance|cell-cell signalling involved in cell-cell junction organization|cell-cell signaling involved in cell-cell junction biogenesis|cell-cell signalling involved in cell-cell junction organisation|cell-cell signalling involved in intercellular junction assembly and maintenance				The reasons for obsoletion are that: (1) the term was created in 2012 and it had been used for only 1 NAS annotation (UniProt) since then; and (2) it can be represented as a GO-CAM.		rph	2012-09-11T09:15:04Z		True				biological_process											owl:Class	
GO:1901424	biolink:NamedThing	response to toluene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus.	got7fsn_ti							tt	2012-10-01T18:38:32Z						biological_process											owl:Class	
GO:0110062	biolink:NamedThing	negative regulation of angiotensin-activated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway.	got7fsn_ti							kmv	2017-10-26T17:42:17Z						biological_process											owl:Class	
GO:0045532	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000063	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57566	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000013	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044583	biolink:NamedThing	cellotriose binding	Binding to cellotriose.	got7fsn_ti							jl	2012-04-24T04:48:01Z						molecular_function											owl:Class	
GO:0070035	biolink:NamedThing	obsolete purine NTP-dependent helicase activity	OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix.	got7fsn_ti					The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo), therefore this term was an unnecessary grouping term.					True				molecular_function											owl:Class	
GO:0051252	biolink:NamedThing	regulation of RNA metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.	got7fsn_ti	regulation of RNA metabolism													biological_process											owl:Class	
GO:0044009	biolink:NamedThing	obsolete viral transmission by vector	OBSOLETE. The transfer of virions by means of an organism (often an insect or other animal) in order to create new infection.	got7fsn_ti					This term was obsoleted because it did not represent a specific process, but represented the life cycle of a virus.					True				biological_process											owl:Class	
GO:1903679	biolink:NamedThing	positive regulation of cap-independent translational initiation	Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation.	got7fsn_ti	up-regulation of cap-independent translational initiation|activation of cap-independent translational initiation|upregulation of cap-independent translational initiation|up regulation of cap-independent translational initiation						bf	2014-11-27T19:52:36Z						biological_process											owl:Class	
GO:0015644	biolink:NamedThing	obsolete lipoprotein antitoxin	OBSOLETE. Binds to a lipoprotein toxin, which is usually derived from a microorganism, thereby neutralizing it.	got7fsn_ti	lipoprotein antitoxin			GO:0015643	This term was made obsolete because it does not represent a function distinct from its parent term.					True				molecular_function											owl:Class	
GO:1900191	biolink:NamedThing	negative regulation of single-species biofilm formation	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.	got7fsn_ti	downregulation of single-species biofilm formation|down-regulation of single-species biofilm formation|down regulation of single-species biofilm formation|inhibition of single-species biofilm formation						di	2012-03-19T12:42:13Z						biological_process											owl:Class	
GO:1904144	biolink:NamedThing	phosphatidylinositol phosphate phosphatase complex	A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity.	got7fsn_ti	prostatic acid phosphatase complex				An example of this is ACPP in human (P15309) in PMID:12525165 (inferred from physical interaction).		bhm	2015-04-14T11:22:53Z						cellular_component											owl:Class	
GO:0046308	biolink:NamedThing	Z-phenylacetaldoxime catabolic process	The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.	got7fsn_ti	Z-phenylacetaldoxime catabolism|Z-phenylacetaldoxime degradation|Z-phenylacetaldoxime breakdown													biological_process											owl:Class	
GO:0021867	biolink:NamedThing	obsolete neuron-producing asymmetric radial glial cell division in forebrain	OBSOLETE. The unequal mitotic division of a radial glial cell in the forebrain that gives rise to a radial glial cell and a post-mitotic neuronal progenitor.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
CL:0000782	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035111	biolink:NamedThing	obsolete leg joint morphogenesis	OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.	got7fsn_ti	leg joint morphogenesis				This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0036023|GO:0016348				True				biological_process											owl:Class	
UBERON:0002870	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008593	biolink:NamedThing	regulation of Notch signaling pathway	Any process that modulates the frequency, rate or extent of the Notch signaling pathway.	got7fsn_ti	regulation of N signaling pathway|regulation of N signalling pathway|regulation of Notch signalling pathway													biological_process											owl:Class	
GO:1905249	biolink:NamedThing	obsolete negative regulation of memory	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of memory.	got7fsn_ti	suppression of memory|inhibition of memory				This term was obsoleted at the TermGenie Gatekeeper stage.		ha	2016-06-09T13:54:45Z		True				biological_process											owl:Class	
GO:0030271	biolink:NamedThing	obsolete chymase activity	OBSOLETE. Catalysis of the preferential cleavage: Phe-Xaa > Tyr-Xaa > Trp-Xaa > Leu-Xaa.	got7fsn_ti	skeletal muscle protease|skin chymotryptic proteinase|mast cell protease I activity|SK protease activity|chymase activity|mast cell serine proteinase|skeletal muscle (SK) protease activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0048379	biolink:NamedThing	positive regulation of lateral mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification.	got7fsn_ti	activation of lateral mesodermal cell fate specification|up regulation of lateral mesodermal cell fate specification|stimulation of lateral mesodermal cell fate specification|positive regulation of lateral plate mesodermal cell fate specification|up-regulation of lateral mesodermal cell fate specification|upregulation of lateral mesodermal cell fate specification													biological_process											owl:Class	
GO:2000541	biolink:NamedThing	positive regulation of protein geranylgeranylation	Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation.	got7fsn_ti	positive regulation of C-terminal protein geranylgeranylation|positive regulation of protein amino acid geranylgeranylation						tb	2011-03-29T06:23:15Z						biological_process											owl:Class	
GO:0000204	biolink:NamedThing	obsolete activation of MAPKK during sporulation (sensu Saccharomyces)	OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	got7fsn_ti	activation of MAPKK during sporulation (sensu Saccharomyces)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0072726	biolink:NamedThing	response to CCCP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus.	got7fsn_ti	response to carbonyl cyanide m-chlorophenyl hydrazone						mah	2012-05-31T11:16:38Z						biological_process											owl:Class	
GO:0009185	biolink:NamedThing	ribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	ribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:1900325	biolink:NamedThing	negative regulation of maltotriulose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport.	got7fsn_ti	downregulation of maltotriulose transport|down regulation of maltotriulose transport|inhibition of maltotriulose transport|down-regulation of maltotriulose transport						tt	2012-04-06T01:48:16Z						biological_process											owl:Class	
GO:0150112	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016219	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900487	biolink:NamedThing	regulation of [2Fe-2S] cluster assembly	Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly.	got7fsn_ti	regulation of [2Fe-2S] cluster biosynthetic process|regulation of 2Fe-2S cluster assembly						tt	2012-05-02T01:22:22Z						biological_process											owl:Class	
GO:1902733	biolink:NamedThing	regulation of growth plate cartilage chondrocyte differentiation	Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti							mr	2014-02-24T16:11:28Z						biological_process											owl:Class	
PR:000001926	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060267	biolink:NamedThing	positive regulation of respiratory burst	Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	got7fsn_ti														biological_process											owl:Class	
GO:0010879	biolink:NamedThing	cholesterol transport involved in cholesterol storage	The directed movement of cholesterol into cells that is part of their accumulation and maintenance.	got7fsn_ti														biological_process											owl:Class	
GO:2000988	biolink:NamedThing	regulation of hemicellulose catabolic process	Any process that modulates the frequency, rate or extent of hemicellulose catabolic process.	got7fsn_ti	regulation of hemicellulose catabolism						tt	2011-08-08T03:08:16Z						biological_process											owl:Class	
GO:0002309	biolink:NamedThing	T cell proliferation involved in immune response	The expansion of a T cell population by cell division as part of an immune response.	got7fsn_ti	T-lymphocyte proliferation during immune response|T cell proliferation during immune response|T lymphocyte proliferation during immune response|T-cell proliferation during immune response													biological_process											owl:Class	
GO:0046329	biolink:NamedThing	negative regulation of JNK cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.	got7fsn_ti	down-regulation of JNK cascade|inhibition of JNK cascade|down regulation of JNK cascade|downregulation of JNK cascade													biological_process											owl:Class	
GO:0019182	biolink:NamedThing	histamine-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:0048004	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050809	biolink:NamedThing	diazepam binding	Binding to diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium.	got7fsn_ti	diazepam binding inhibitor activity|Valium binding													molecular_function											owl:Class	
GO:0010713	biolink:NamedThing	negative regulation of collagen metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	got7fsn_ti														biological_process											owl:Class	
GO:0032538	biolink:NamedThing	regulation of host-seeking behavior	Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism.	got7fsn_ti	regulation of host-seeking behaviour													biological_process											owl:Class	
GO:0032975	biolink:NamedThing	amino acid transmembrane import into vacuole	The directed movement of amino acids into the vacuole across the vacuolar membrane.	got7fsn_ti	vacuolar amino acid import													biological_process											owl:Class	
GO:0015526	biolink:NamedThing	hexose-phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out).	got7fsn_ti														molecular_function											owl:Class	
GO:1902744	biolink:NamedThing	negative regulation of lamellipodium organization	Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization.	got7fsn_ti	downregulation of lamellipodium organization|down regulation of lamellipodium organization|down-regulation of lamellipodium organization|inhibition of lamellipodium organization						als	2014-02-28T16:27:39Z						biological_process											owl:Class	
GO:0032375	biolink:NamedThing	negative regulation of cholesterol transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	downregulation of cholesterol transport|down regulation of cholesterol transport|inhibition of cholesterol transport|down-regulation of cholesterol transport													biological_process											owl:Class	
GO:1901260	biolink:NamedThing	peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification	Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification.	got7fsn_ti	EF-P lysine hydroxylation						bf	2012-08-14T13:20:12Z						biological_process											owl:Class	
GO:0019508	biolink:NamedThing	2,5-dihydroxypyridine catabolic process to fumarate	The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate.	got7fsn_ti	pyridine-2,5-diol catabolic process to fumarate|2,5-dihydroxypyridine degradation to fumarate|2,5-dihydroxypyridine breakdown to fumarate|2,5-dihydroxypyridine utilization|maleamate pathway											MetaCyc:PWY-722		biological_process											owl:Class	
GO:0003930	biolink:NamedThing	obsolete RAS small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	RAS small monomeric GTPase activity			GO:0003924	This term was made obsolete because it represents a gene product.	GO:0001558				True				molecular_function											owl:Class	
GO:0002575	biolink:NamedThing	basophil chemotaxis	The movement of a basophil in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:1904895	biolink:NamedThing	ESCRT complex assembly	The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex.	got7fsn_ti	endosomal sorting complex required for transport assembly|ESCRT complex formation|endosomal sorting complex required for transport formation						pad	2016-01-12T10:27:11Z						biological_process											owl:Class	
GO:2000990	biolink:NamedThing	positive regulation of hemicellulose catabolic process	Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process.	got7fsn_ti	positive regulation of hemicellulose catabolism						tt	2011-08-08T03:08:23Z						biological_process											owl:Class	
GO:1900993	biolink:NamedThing	(-)-secologanin catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-secologanin.	got7fsn_ti	(-)-secologanin degradation|(-)-secologanin breakdown|(-)-secologanin catabolism						yaf	2012-06-14T09:51:39Z						biological_process											owl:Class	
GO:0043134	biolink:NamedThing	regulation of hindgut contraction	Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0031079	biolink:NamedThing	obsolete picornain 3C activity	OBSOLETE. Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.	got7fsn_ti	foot-and-mouth-disease virus proteinase 3C|3C protease activity|protease 3C|coxsackievirus 3C proteinase activity|rhinovirus proteinase 3C|cysteine proteinase 3C|3C proteinase activity|picornain 3C activity|tomato ringspot nepovirus 3C-related protease|poliovirus proteinase 3C|poliovirus protease 3C activity|foot-and-mouth protease 3C activity|rhinovirus protease 3C activity|hepatitis A virus 3C proteinase activity|picornavirus endopeptidase 3C activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0061954	biolink:NamedThing	positive regulation of actin filament polymerization involved in sperm capacitation	Any process that icreases the rate or extent of actin polymerization as part of sperm capacitation. This process prevents a spontaneous acrosome reaction.	got7fsn_ti							dph	2017-11-10T19:40:00Z						biological_process											owl:Class	
GO:0030190	biolink:NamedThing	obsolete chaperone inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of a molecular chaperone.	got7fsn_ti	chaperone inhibitor activity				This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'.	GO:0051082|GO:0051787|GO:0006457				True				molecular_function											owl:Class	
GO:0030446	biolink:NamedThing	hyphal cell wall	The cell wall surrounding a fungal hypha.	got7fsn_ti					See also the Fungal Anatomy Ontology term 'hypha ; FAO:0001001'.									cellular_component											owl:Class	
GO:0033138	biolink:NamedThing	positive regulation of peptidyl-serine phosphorylation	Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.	got7fsn_ti														biological_process											owl:Class	
GO:0001685	biolink:NamedThing	obsolete axonemal dynein intermediate light chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	axonemal dynein intermediate light chain			GO:0005858	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:2000449	biolink:NamedThing	regulation of CD8-positive, alpha-beta T cell extravasation	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.	got7fsn_ti							bf	2011-03-04T10:41:03Z						biological_process											owl:Class	
GO:0070163	biolink:NamedThing	regulation of adiponectin secretion	Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0019699	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019338	biolink:NamedThing	pentachlorophenol catabolic process	The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.	got7fsn_ti	pentachlorophenol breakdown|pentachlorophenol degradation|pentachlorophenol catabolism											MetaCyc:PCPDEG-PWY		biological_process											owl:Class	
GO:1900122	biolink:NamedThing	positive regulation of receptor binding	Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor.	got7fsn_ti	activation of receptor binding|up regulation of receptor binding|upregulation of receptor binding						bf	2012-02-22T11:41:00Z						biological_process											owl:Class	
GO:0050756	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098554	biolink:NamedThing	cytoplasmic side of endoplasmic reticulum membrane	The side (leaflet) of the plasma membrane that faces the cytoplasm.	got7fsn_ti							dos	2013-12-03T12:09:47Z						cellular_component											owl:Class	
CHEBI:58711	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004204	biolink:NamedThing	obsolete caspase-5 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	caspase-5 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0098551	biolink:NamedThing	lumenal side of late endosome membrane	The side (leaflet) of the late endosome membrane that faces the lumen.	got7fsn_ti	internal side of late endosome membrane|internal leaflet of late endosome membrane													cellular_component											owl:Class	
GO:0009076	biolink:NamedThing	obsolete histidine family amino acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of amino acids of the histidine family.	got7fsn_ti	histidine family amino acid anabolism|histidine family amino acid synthesis|histidine family amino acid biosynthetic process|histidine family amino acid formation|histidine family amino acid biosynthesis			GO:0000105	This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family.					True				biological_process											owl:Class	
GO:1905164	biolink:NamedThing	positive regulation of phagosome maturation	Any process that activates or increases the frequency, rate or extent of phagosome maturation.	got7fsn_ti	upregulation of phagosome maturation|up regulation of phagosome maturation|activation of phagosome maturation|up-regulation of phagosome maturation						bf	2016-04-25T16:28:19Z						biological_process											owl:Class	
GO:1902731	biolink:NamedThing	negative regulation of chondrocyte proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.	got7fsn_ti	inhibition of chondrocyte proliferation|inhibition of chondrocyte cell proliferation|downregulation of cartilage cell proliferation|inhibition of cartilage cell proliferation|down-regulation of chondrocyte cell proliferation|down regulation of cartilage cell proliferation|down-regulation of cartilage cell proliferation|negative regulation of chondrocyte cell proliferation|down regulation of chondrocyte cell proliferation|negative regulation of cartilage cell proliferation|downregulation of chondrocyte cell proliferation|down-regulation of chondrocyte proliferation|downregulation of chondrocyte proliferation|down regulation of chondrocyte proliferation						mr	2014-02-24T16:11:02Z						biological_process											owl:Class	
GO:0018912	biolink:NamedThing	1,4-dichlorobenzene metabolic process	The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs.	got7fsn_ti	1,4-dichlorobenzene metabolism											UM-BBD_pathwayID:dcz		biological_process											owl:Class	
GO:0044069	biolink:NamedThing	modulation by symbiont of host anion transport	The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism.	got7fsn_ti	modification of host anion transport by symbiont													biological_process											owl:Class	
GO:0018916	biolink:NamedThing	nitrobenzene metabolic process	The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline.	got7fsn_ti	nitrobenzene metabolism											UM-BBD_pathwayID:nb		biological_process											owl:Class	
GO:0060803	biolink:NamedThing	BMP signaling pathway involved in mesodermal cell fate specification	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate.	got7fsn_ti	BMP signalling pathway involved in mesodermal cell fate specification						dph	2009-08-06T01:47:39Z						biological_process											owl:Class	
GO:0090206	biolink:NamedThing	negative regulation of cholesterol metabolic process	Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti							tb	2009-12-23T10:27:37Z						biological_process											owl:Class	
GO:0099117	biolink:NamedThing	protein transport along microtubule to cell tip	The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins.	got7fsn_ti							vw	2015-09-15T11:09:54Z						biological_process											owl:Class	
GO:0140075	biolink:NamedThing	regulation of lipoprotein transport	Any process that controls lipoprotein transport.	got7fsn_ti							pg	2017-07-21T15:35:47Z						biological_process											owl:Class	
GO:0019637	biolink:NamedThing	organophosphate metabolic process	The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.	got7fsn_ti	organophosphate metabolism													biological_process											owl:Class	
GO:1904656	biolink:NamedThing	regulation of sensory perception of sweet taste	Any process that modulates the frequency, rate or extent of sensory perception of sweet taste.	got7fsn_ti	regulation of sweet taste perception						mr	2015-09-04T16:43:12Z						biological_process											owl:Class	
GO:0033664	biolink:NamedThing	obsolete positive regulation by symbiont of host defense-related protein level	OBSOLETE. Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it is a readout, and annotations should be made to more informative terms.					True				biological_process											owl:Class	
CHEBI:60481	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902352	biolink:NamedThing	obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of filamentous growth of a population of unicellular organisms in response to starvation.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		bf	2013-08-14T09:35:43Z		True				biological_process											owl:Class	
GO:0043172	biolink:NamedThing	obsolete ferredoxin biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.	got7fsn_ti	ferredoxin anabolism|ferredoxin synthesis|ferredoxin biosynthesis|ferredoxin formation				This term was made obsolete because it refers to biosynthesis of a protein.					True				biological_process											owl:Class	
GO:2000618	biolink:NamedThing	regulation of histone H4-K16 acetylation	Any process that modulates the frequency, rate or extent of histone H4-K16 acetylation.	got7fsn_ti	regulation of histone H4 acetylation at K16						vk	2011-04-18T03:19:23Z						biological_process											owl:Class	
GO:2000671	biolink:NamedThing	regulation of motor neuron apoptotic process	Any process that modulates the frequency, rate or extent of motor neuron apoptotic process.	got7fsn_ti	regulation of motor neuron apoptosis|regulation of motoneuron apoptosis						pr	2011-05-09T10:56:17Z						biological_process											owl:Class	
GO:0050648	biolink:NamedThing	5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Binding to 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.	got7fsn_ti	5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding													molecular_function											owl:Class	
OIO:inSubset	biolink:NamedThing	in_subset		got7fsn_ti																									owl:AnnotationProperty	
GO:0052353	biolink:NamedThing	obsolete catabolism by host of symbiont carbohydrate	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0009141	biolink:NamedThing	nucleoside triphosphate metabolic process	The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	nucleoside triphosphate metabolism													biological_process											owl:Class	
GO:2000334	biolink:NamedThing	positive regulation of blood microparticle formation	Any process that activates or increases the frequency, rate or extent of blood microparticle formation.	got7fsn_ti	positive regulation of microparticle generation|positive regulation of microparticle release						mah	2011-01-31T11:18:23Z						biological_process											owl:Class	
GO:0019687	biolink:NamedThing	pyruvate biosynthetic process from acetate	The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate.	got7fsn_ti	pyruvate anabolism from acetate|pyruvate synthesis from acetate|pyruvate formation from acetate													biological_process											owl:Class	
GO:0032665	biolink:NamedThing	regulation of interleukin-21 production	Any process that modulates the frequency, rate, or extent of interleukin-21 production.	got7fsn_ti	regulation of interleukin-21 biosynthetic process|regulation of IL-21 production										GO:0045390			biological_process											owl:Class	
CHEBI:57873	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043497	biolink:NamedThing	regulation of protein heterodimerization activity	Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.	got7fsn_ti					Note that protein heterodimerization is a molecular function: 'protein heterodimerization activity ; GO:0046982'.									biological_process											owl:Class	
GO:2000861	biolink:NamedThing	regulation of estrogen secretion	Any process that modulates the frequency, rate or extent of estrogen secretion.	got7fsn_ti	regulation of oestrogen secretion						bf	2011-07-26T08:48:24Z						biological_process											owl:Class	
GO:0005280	biolink:NamedThing	amino acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in).	got7fsn_ti	cation/amino acid symporter|hydrogen:amino acid symporter activity											Reactome:R-HSA-8875623		molecular_function											owl:Class	
CHEBI:18262	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0039569	biolink:NamedThing	obsolete suppression by virus of host STAT2 activity by positive regulation of STAT2 catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT2 (signal transducer and activator of transcription-2) by promoting the ubiquitin-dependent degradation of STAT2, mediated by the proteasome.	got7fsn_ti	suppression by virus of host STAT2 activity by positive promotion of STAT2 proteasome-mediated degradation|promotion by virus of proteosome-dependent STAT2 degradation|targeting STAT2 for proteasome-mediated degradation				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:43:44Z		True				biological_process											owl:Class	
GO:0045223	biolink:NamedThing	regulation of CD4 production	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.	got7fsn_ti	regulation of CD4 formation|regulation of CD4 synthesis|regulation of CD4 biosynthetic process|regulation of CD4 anabolism|regulation of CD4 biosynthesis													biological_process											owl:Class	
GO:0071530	biolink:NamedThing	obsolete FHA domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an FHA (forkhead-associated) domain interaction.	got7fsn_ti	forkhead-associated domain-mediated complex assembly				This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T01:57:36Z		True				biological_process											owl:Class	
GO:1902071	biolink:NamedThing	regulation of hypoxia-inducible factor-1alpha signaling pathway	Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.	got7fsn_ti	regulation of hypoxia-inducible factor-1alpha signalling pathway|regulation of HIF1alpha pathway						bf	2013-04-18T13:28:21Z						biological_process											owl:Class	
GO:0045070	biolink:NamedThing	positive regulation of viral genome replication	Any process that activates or increases the frequency, rate or extent of viral genome replication.	got7fsn_ti	up-regulation of viral genome replication|stimulation of viral genome replication|upregulation of viral genome replication|activation of viral genome replication|up regulation of viral genome replication													biological_process											owl:Class	
GO:0006844	biolink:NamedThing	acyl carnitine transport	The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.	got7fsn_ti														biological_process											owl:Class	
GO:1901926	biolink:NamedThing	cadinene metabolic process	The chemical reactions and pathways involving cadinene.	got7fsn_ti	cadinene metabolism						ms	2013-02-18T14:54:22Z						biological_process											owl:Class	
GO:0070951	biolink:NamedThing	regulation of neutrophil mediated killing of gram-negative bacterium	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.	got7fsn_ti							mah	2009-10-01T02:14:36Z						biological_process											owl:Class	
GO:1903107	biolink:NamedThing	insulin receptor signaling pathway involved in dauer larval development	Any insulin receptor signaling pathway that is involved in dauer larval development.	got7fsn_ti	daf-2 receptor signaling pathway involved in dauer larval development|insulin receptor signalling pathway involved in dauer larval development						kmv	2014-06-05T21:30:03Z						biological_process											owl:Class	
GO:0043208	biolink:NamedThing	glycosphingolipid binding	Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.	got7fsn_ti														molecular_function											owl:Class	
GO:0045585	biolink:NamedThing	positive regulation of cytotoxic T cell differentiation	Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation.	got7fsn_ti	positive regulation of cytotoxic T lymphocyte differentiation|upregulation of cytotoxic T cell differentiation|up regulation of cytotoxic T cell differentiation|positive regulation of cytotoxic T-cell differentiation|positive regulation of cytotoxic T-lymphocyte differentiation|up-regulation of cytotoxic T cell differentiation|stimulation of cytotoxic T cell differentiation|positive regulation of cytotoxic T cell development|activation of cytotoxic T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0047497	biolink:NamedThing	mitochondrion transport along microtubule	The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.	got7fsn_ti	mitochondrial migration along microtubule|mitochondrial transport along microtubule													biological_process											owl:Class	
GO:0047138	biolink:NamedThing	obsolete aquacobalamin reductase activity	OBSOLETE. Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+.	got7fsn_ti	cob(II)alamin:NAD+ oxidoreductase activity|NADH2:cob(III)alamin oxidoreductase activity|B12a reductase activity|aquocobalamin reductase activity|NADH-linked aquacobalamin reductase activity|vitamin B12a reductase activity|B(12a) reductase activity|NADH:cob(III)alamin oxidoreductase activity|vitamin B(12a) reductase activity	https://github.com/geneontology/go-ontology/issues/20679			The term was obsoleted because it is not known to be catalyzed by any gene product.					True		RHEA:24472|EC:1.16.1.3|MetaCyc:AQUACOBALAMIN-REDUCTASE-RXN		molecular_function											owl:Class	
GO:0006147	biolink:NamedThing	guanine catabolic process	The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.	got7fsn_ti	guanine catabolism|guanine breakdown|guanine degradation													biological_process											owl:Class	
GO:0075094	biolink:NamedThing	obsolete positive regulation by host of symbiont signal transduction mediated by G-protein beta subunit	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0016357	biolink:NamedThing	obsolete pyrethroid susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	pyrethroid susceptibility/resistance			GO:0046684	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0046113	biolink:NamedThing	nucleobase catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.	got7fsn_ti	nucleobase breakdown|nucleobase catabolism|nucleobase degradation													biological_process											owl:Class	
GO:0032553	biolink:NamedThing	ribonucleotide binding	Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	got7fsn_ti														molecular_function											owl:Class	
GO:1900782	biolink:NamedThing	fumiquinazoline F metabolic process	The chemical reactions and pathways involving fumiquinazoline F.	got7fsn_ti	fumiquinazoline F metabolism						di	2012-06-04T09:31:06Z						biological_process											owl:Class	
GO:0052052	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type II secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type II secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:1905935	biolink:NamedThing	positive regulation of cell fate determination	Any process that activates or increases the frequency, rate or extent of cell fate determination.	got7fsn_ti	up regulation of cell fate determination|activation of cell fate determination|upregulation of cell fate determination|up-regulation of cell fate determination						bhm	2017-02-09T11:25:38Z						biological_process											owl:Class	
GO:0015496	biolink:NamedThing	putrescine:ornithine antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out).	got7fsn_ti	putrescine-ornithine antiporter activity|putrescine/ornithine antiporter activity|putrescine:hydrogen symporter activity													molecular_function											owl:Class	
GO:0150136	biolink:NamedThing	regulation of interleukin-37 production	Any process that modulates the frequency, rate or extent of interleukin-37 production.	got7fsn_ti	regulation of interleukin-37 biosynthetic process						bc	2019-12-08T08:39:07Z						biological_process											owl:Class	
GO:0070296	biolink:NamedThing	sarcoplasmic reticulum calcium ion transport	The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.	got7fsn_ti														biological_process											owl:Class	
GO:0120251	biolink:NamedThing	hydrocarbon biosynthetic process	The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only.	got7fsn_ti	hydrocarbon anabolism|hydrocarbon biosynthesis|hydrocarbon formation|hydrocarbon synthesis	https://github.com/geneontology/go-ontology/issues/19842					krc	2020-09-02T20:35:53Z						biological_process											owl:Class	
GO:1904571	biolink:NamedThing	positive regulation of selenocysteine incorporation	Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation.	got7fsn_ti	upregulation of selenocysteine incorporation|up regulation of selenocysteine incorporation|activation of selenocysteine incorporation|up-regulation of selenocysteine incorporation						sl	2015-08-19T17:26:50Z						biological_process											owl:Class	
GO:0046438	biolink:NamedThing	D-cysteine metabolic process	The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.	got7fsn_ti	D-cysteine metabolism													biological_process											owl:Class	
UBERON:0005148	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051630	biolink:NamedThing	acetylcholine uptake	The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	got7fsn_ti	acetylcholine import													biological_process											owl:Class	
GO:0046083	biolink:NamedThing	adenine metabolic process	The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.	got7fsn_ti	adenine metabolism													biological_process											owl:Class	
GO:0030804	biolink:NamedThing	obsolete positive regulation of cyclic nucleotide biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.	got7fsn_ti	up regulation of cyclic nucleotide biosynthetic process|positive regulation of cyclic nucleotide anabolism|up-regulation of cyclic nucleotide biosynthetic process|stimulation of cyclic nucleotide biosynthetic process|activation of cyclic nucleotide biosynthetic process|upregulation of cyclic nucleotide biosynthetic process|positive regulation of cyclic nucleotide synthesis|positive regulation of cyclic nucleotide biosynthesis|positive regulation of cyclic nucleotide formation				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:2000810	biolink:NamedThing	regulation of bicellular tight junction assembly	Any process that modulates the frequency, rate or extent of tight junction assembly.	got7fsn_ti	regulation of tight junction formation						vk	2011-07-06T01:08:28Z						biological_process											owl:Class	
GO:0046453	biolink:NamedThing	dipyrrin metabolic process	The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.	got7fsn_ti	dipyrrin metabolism													biological_process											owl:Class	
GO:2001212	biolink:NamedThing	regulation of vasculogenesis	Any process that modulates the frequency, rate or extent of vasculogenesis.	got7fsn_ti	regulation of vascular morphogenesis						yaf	2011-11-15T01:22:31Z						biological_process											owl:Class	
GO:0033148	biolink:NamedThing	positive regulation of intracellular estrogen receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.	got7fsn_ti	positive regulation of estrogen receptor signaling pathway|positive regulation of estrogen receptor signalling pathway													biological_process											owl:Class	
GO:0060028	biolink:NamedThing	convergent extension involved in axis elongation	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.	got7fsn_ti														biological_process											owl:Class	
UBERON:0003946	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000407	biolink:NamedThing	regulation of T cell extravasation	Any process that modulates the frequency, rate or extent of T cell extravasation.	got7fsn_ti	regulation of T lymphocyte extravasation|regulation of T-lymphocyte extravasation|regulation of T-cell extravasation						mah	2011-02-23T10:51:58Z						biological_process											owl:Class	
GO:0005504	biolink:NamedThing	fatty acid binding	Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.	got7fsn_ti														molecular_function											owl:Class	
GO:0052107	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:53071	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905626	biolink:NamedThing	positive regulation of L-methionine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane.	got7fsn_ti							vw	2016-10-29T16:27:46Z						biological_process											owl:Class	
GO:0032309	biolink:NamedThing	icosanoid secretion	The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.	got7fsn_ti	eicosanoid secretion													biological_process											owl:Class	
GO:1901646	biolink:NamedThing	negative regulation of synoviocyte proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.	got7fsn_ti	down regulation of synoviocyte proliferation|down-regulation of synoviocyte proliferation|downregulation of synoviocyte proliferation|inhibition of synoviocyte proliferation						hjd	2012-11-16T20:16:27Z						biological_process											owl:Class	
GO:0003799	biolink:NamedThing	obsolete antifungal peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, fungal cells.	got7fsn_ti	antifungal peptide activity				This term was made obsolete because it describes involvement in a process and not a function.	GO:0050832				True				molecular_function											owl:Class	
GO:0007251	biolink:NamedThing	obsolete activation of the inhibitor of kappa kinase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of the inhibitor of kappa kinase				This term was made obsolete because its meaning was unclear.	GO:0007249				True				biological_process											owl:Class	
GO:1990816	biolink:NamedThing	vacuole-mitochondrion membrane contact site	A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.	got7fsn_ti	vCLAMP|vacuole and mitochondria patch						mcc	2015-07-29T21:06:41Z						cellular_component											owl:Class	
GO:0008435	biolink:NamedThing	obsolete anticoagulant activity	OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation.	got7fsn_ti	anticoagulant activity			GO:0050819	This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:2001144	biolink:NamedThing	regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.	got7fsn_ti							yaf	2011-10-19T10:41:25Z						biological_process											owl:Class	
GO:0042058	biolink:NamedThing	regulation of epidermal growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.	got7fsn_ti	regulation of EGF receptor signaling pathway|regulation of EGFR signaling pathway|regulation of EGF receptor signalling pathway													biological_process											owl:Class	
GO:0097174	biolink:NamedThing	1,6-anhydro-N-acetyl-beta-muramic acid metabolic process	The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.	got7fsn_ti	1,6-anhydro-N-acetylmuramic acid metabolic process|1,6-anhydro-N-acetyl-beta-muramate metabolic process|1,6-anhydro-N-acetyl-beta-muramate metabolism|1,6-anhydro-N-acetyl-beta-muramic acid metabolism|1,6-anhydro-N-acetylmuramic acid metabolism						pr	2011-10-07T12:54:36Z						biological_process											owl:Class	
GO:2000989	biolink:NamedThing	negative regulation of hemicellulose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process.	got7fsn_ti	negative regulation of hemicellulose catabolism						tt	2011-08-08T03:08:20Z						biological_process											owl:Class	
GO:0060552	biolink:NamedThing	positive regulation of fructose 1,6-bisphosphate metabolic process	Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.	got7fsn_ti							dph	2009-04-13T02:23:40Z						biological_process											owl:Class	
GO:0060621	biolink:NamedThing	negative regulation of cholesterol import	Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.	got7fsn_ti							dph	2009-05-18T01:46:21Z						biological_process											owl:Class	
GO:0052115	biolink:NamedThing	obsolete energy taxis in host environment	OBSOLETE. The directed movement of a motile cell or organism in the environment of its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	energy taxis in response to host environment				This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0098548	biolink:NamedThing	cytoplasmic side of Golgi membrane	The side (leaflet) of the Golgi membrane that faces the cytoplasm.	got7fsn_ti							dos	2013-12-03T10:49:33Z						cellular_component											owl:Class	
GO:0008244	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140256	biolink:NamedThing	negative regulation of cellular response to phosphate starvation	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation.	got7fsn_ti							pg	2018-09-07T17:11:42Z						biological_process											owl:Class	
GO:1905677	biolink:NamedThing	regulation of adaptive immune effector response	Any process that modulates the frequency, rate or extent of adaptive immune effector response.	got7fsn_ti							tb	2016-11-11T22:24:57Z						biological_process											owl:Class	
GO:2000270	biolink:NamedThing	negative regulation of fibroblast apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.	got7fsn_ti	negative regulation of fibroblast apoptosis						jl	2010-11-23T01:07:27Z						biological_process											owl:Class	
CHEBI:64695	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075014	biolink:NamedThing	obsolete growth or development of symbiont on or near host rhizosphere	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of symbiont on or near host rhizosphere									True				biological_process											owl:Class	
GO:1905320	biolink:NamedThing	regulation of mesenchymal stem cell migration	Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration.	got7fsn_ti							sl	2016-07-15T22:19:14Z						biological_process											owl:Class	
GO:0036197	biolink:NamedThing	zymosterol biosynthetic process	The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).	got7fsn_ti	zymosterol synthesis|zymosterol biosynthesis|zymosterol anabolism|zymosterol formation						bf	2012-04-20T10:28:46Z				UniPathway:UPA00770|MetaCyc:PWY-6074		biological_process											owl:Class	
GO:0050948	biolink:NamedThing	positive regulation of early stripe melanocyte differentiation	Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation.	got7fsn_ti	up-regulation of early stripe melanocyte differentiation|stimulation of early stripe melanocyte differentiation|positive regulation of early stripe melanophore differentiation|activation of early stripe melanocyte differentiation|upregulation of early stripe melanocyte differentiation|up regulation of early stripe melanocyte differentiation													biological_process											owl:Class	
UBERON:0000115	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901541	biolink:NamedThing	ent-pimara-8(14),15-diene biosynthetic process	The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene.	got7fsn_ti	ent-pimara-8(14),15-diene synthesis|ent-pimara-8(14),15-diene anabolism|ent-pimara-8(14),15-diene formation|ent-pimara-8(14),15-diene biosynthesis						di	2012-10-25T15:38:21Z						biological_process											owl:Class	
GO:0034329	biolink:NamedThing	cell junction assembly	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.	got7fsn_ti														biological_process											owl:Class	
GO:0005346	biolink:NamedThing	purine ribonucleotide transmembrane transporter activity	Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
GO:1901927	biolink:NamedThing	cadinene catabolic process	The chemical reactions and pathways resulting in the breakdown of cadinene.	got7fsn_ti	cadinene breakdown|cadinene catabolism|cadinene degradation						ms	2013-02-18T14:54:29Z						biological_process											owl:Class	
GO:0106289	biolink:NamedThing	negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA	Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.	got7fsn_ti							hjd	2020-08-13T17:12:33Z						biological_process											owl:Class	
GO:0033298	biolink:NamedThing	contractile vacuole organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.	got7fsn_ti	contractile vacuole organisation|contractile vacuole organization and biogenesis													biological_process											owl:Class	
GO:0042480	biolink:NamedThing	negative regulation of eye photoreceptor cell development	Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development.	got7fsn_ti	down-regulation of eye photoreceptor cell development|negative regulation of eye photoreceptor development|inhibition of eye photoreceptor cell development|downregulation of eye photoreceptor cell development|down regulation of eye photoreceptor cell development													biological_process											owl:Class	
GO:1901619	biolink:NamedThing	obsolete tRNA methylation in response to nitrogen starvation	OBSOLETE. The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule as a result of deprivation of nitrogen.	got7fsn_ti							al	2012-11-13T14:36:00Z		True				biological_process											owl:Class	
GO:0002325	biolink:NamedThing	natural killer cell differentiation involved in immune response	The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response.	got7fsn_ti	NK cell differentiation during immune response|natural killer cell development involved in immune response|natural killer cell differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0075278	biolink:NamedThing	negative regulation of telium development	Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0060258	biolink:NamedThing	negative regulation of filamentous growth	Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.	got7fsn_ti														biological_process											owl:Class	
GO:1901780	biolink:NamedThing	pentalenolactone biosynthetic process	The chemical reactions and pathways resulting in the formation of pentalenolactone.	got7fsn_ti	pentalenolactone biosynthesis|pentalenolactone formation|pentalenolactone synthesis|pentalenolactone anabolism						yaf	2013-01-16T09:49:47Z						biological_process											owl:Class	
GO:0100052	biolink:NamedThing	obsolete negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates G1/S transition of mitotic cell cycle.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0003709	biolink:NamedThing	obsolete RNA polymerase III transcription factor activity	OBSOLETE. Functions to initiate or regulate RNA polymerase III transcription.	got7fsn_ti	RNA polymerase III transcription factor activity				This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0000995|GO:0006383				True				molecular_function											owl:Class	
GO:0002816	biolink:NamedThing	regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.	got7fsn_ti														biological_process											owl:Class	
CHEBI:32564	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010764	biolink:NamedThing	negative regulation of fibroblast migration	Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.	got7fsn_ti	negative regulation of fibroblast cell migration													biological_process											owl:Class	
GO:0046245	biolink:NamedThing	obsolete styrene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.	got7fsn_ti	styrene biosynthetic process|styrene biosynthesis|styrene anabolism|styrene synthesis|styrene formation			GO:0018966	This term was made obsolete because styrene is not synthesized by living organisms and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0008950	biolink:NamedThing	obsolete p-aminobenzoate synthetase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	p-aminobenzoate synthetase				This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered.	GO:0008696|GO:0046820				True				molecular_function											owl:Class	
GO:1903777	biolink:NamedThing	melibiose binding	Binding to melibiose.	got7fsn_ti							mr	2015-01-06T21:05:29Z						molecular_function											owl:Class	
GO:0090265	biolink:NamedThing	positive regulation of immune complex clearance by monocytes and macrophages	Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.	got7fsn_ti							tb	2010-02-04T04:32:18Z						biological_process											owl:Class	
GO:0090352	biolink:NamedThing	regulation of nitrate assimilation	Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances.	got7fsn_ti							tb	2010-06-10T04:11:13Z						biological_process											owl:Class	
GO:0044285	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019442	biolink:NamedThing	tryptophan catabolic process to acetyl-CoA	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.	got7fsn_ti	tryptophan degradation to acetyl-CoA|tryptophan breakdown to acetyl-CoA											MetaCyc:TRYPTOPHAN-DEGRADATION-1		biological_process											owl:Class	
GO:0009196	biolink:NamedThing	pyrimidine deoxyribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0062169	biolink:NamedThing	regulation of plus-end directed microtubule sliding	Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding.	got7fsn_ti							dph	2019-11-12T18:01:32Z						biological_process											owl:Class	
GO:2000961	biolink:NamedThing	negative regulation of cellooligosaccharide metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process.	got7fsn_ti	negative regulation of cellooligosaccharide metabolism						tt	2011-08-01T02:25:59Z						biological_process											owl:Class	
GO:0032337	biolink:NamedThing	positive regulation of activin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.	got7fsn_ti	activation of activin secretion|stimulation of activin secretion|upregulation of activin secretion|up-regulation of activin secretion|up regulation of activin secretion													biological_process											owl:Class	
GO:0009178	biolink:NamedThing	pyrimidine deoxyribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside monophosphate breakdown|pyrimidine deoxyribonucleoside monophosphate degradation|pyrimidine deoxyribonucleoside monophosphate catabolism													biological_process											owl:Class	
GO:0001619	biolink:NamedThing	obsolete lysosphingolipid and lysophosphatidic acid receptor activity	OBSOLETE. Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity.	got7fsn_ti	lysosphingolipid and lysophosphatidic acid receptor activity					GO:0038036|GO:0070915				True				molecular_function											owl:Class	
GO:0019262	biolink:NamedThing	N-acetylneuraminate catabolic process	The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.	got7fsn_ti	N-acetylneuraminate breakdown|N-acetylneuraminate catabolism|N-acetylneuraminate degradation											MetaCyc:P441-PWY		biological_process											owl:Class	
GO:0000231	biolink:NamedThing	obsolete cytoplasmic mitotic chromosome	OBSOLETE. A chromosome found in the cytoplasm during mitosis.	got7fsn_ti	cytoplasmic mitotic chromosome				This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000793				True				cellular_component											owl:Class	
GO:1900114	biolink:NamedThing	positive regulation of histone H3-K9 trimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation.	got7fsn_ti	upregulation of histone H3-K9 trimethylation|activation of histone H3-K9 trimethylation|up regulation of histone H3-K9 trimethylation|up-regulation of histone H3-K9 trimethylation						bf	2012-02-21T09:09:58Z						biological_process											owl:Class	
CHEBI:26907	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046712	biolink:NamedThing	GDP catabolic process	The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate.	got7fsn_ti	GDP degradation|GDP catabolism|GDP breakdown													biological_process											owl:Class	
GO:1901644	biolink:NamedThing	obsolete positive regulation of tRNA methylation in response to nitrogen starvation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of tRNA methylation in response to nitrogen starvation.	got7fsn_ti	up regulation of tRNA methylation in response to nitrogen starvation|up-regulation of tRNA methylation in response to nitrogen starvation|upregulation of tRNA methylation in response to nitrogen starvation|activation of tRNA methylation in response to nitrogen starvation						al	2012-11-16T14:44:12Z		True				biological_process											owl:Class	
GO:0048777	biolink:NamedThing	positive regulation of leucophore differentiation	Any process that activates or increases the frequency, rate or extent of leucophore differentiation.	got7fsn_ti	activation of leucophore differentiation|upregulation of leucophore differentiation|stimulation of leucophore differentiation|up-regulation of leucophore differentiation|up regulation of leucophore differentiation													biological_process											owl:Class	
GO:0052046	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via secreted substance	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by one of the organisms. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification of host morphology or physiology via ellicitor|modification of host morphology or physiology via effector molecule				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:1900411	biolink:NamedThing	obsolete regulation of histone acetylation by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone acetylation.	got7fsn_ti					This term was obsoleted because it describes a process that does not exist.		mah	2012-04-20T03:35:22Z		True				biological_process											owl:Class	
GO:1905370	biolink:NamedThing	serine-type endopeptidase complex	A protein complex which is capable of serine-type endopeptidase activity.	got7fsn_ti					An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay).		bhm	2016-08-16T13:09:57Z						cellular_component											owl:Class	
CHEBI:26537	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904434	biolink:NamedThing	positive regulation of ferrous iron binding	Any process that activates or increases the frequency, rate or extent of ferrous iron binding.	got7fsn_ti	upregulation of ferrous iron binding|up regulation of ferrous iron binding|activation of ferrous iron binding|up-regulation of ferrous iron binding						kom	2015-07-06T13:46:42Z						biological_process											owl:Class	
GO:0010574	biolink:NamedThing	regulation of vascular endothelial growth factor production	Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor.	got7fsn_ti														biological_process											owl:Class	
GO:0019472	biolink:NamedThing	4-hydroxyproline biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.	got7fsn_ti	4-hydroxyproline synthesis|4-hydroxyproline biosynthesis|4-hydroxyproline formation|4-hydroxyproline anabolism													biological_process											owl:Class	
GO:0038011	biolink:NamedThing	negative regulation of signal transduction by receptor internalization	Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.	got7fsn_ti	negative regulation of signaling pathway by receptor endocytosis						bf	2011-06-23T03:39:06Z						biological_process											owl:Class	
GO:0052426	biolink:NamedThing	obsolete modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system	OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type IV secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0106280	biolink:NamedThing	positive regulation of UDP-N-acetylglucosamine biosynthetic process	Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.	got7fsn_ti	positive regulation of UDP-N-acetylglucosamine synthesis|positive regulation of UDP-GlcNAc biosynthetic process|positive regulation of UDP-N-acetylglucosamine anabolism|positive egulation of UDP-N-acetylglucosamine formation|positive regulation of UDP-N-acetylglucosamine biosynthesis						hjd	2020-07-09T18:12:08Z						biological_process											owl:Class	
GO:2001081	biolink:NamedThing	(1->4)-beta-D-galactan binding	Binding to (1->4)-beta-D-galactan.	got7fsn_ti	(1,4)-beta-D-galactan binding						jl	2011-09-15T01:21:50Z						molecular_function											owl:Class	
GO:0019020	biolink:NamedThing	obsolete multipartite viral genome	OBSOLETE. A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
CHEBI:27417	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904887	biolink:NamedThing	Wnt signalosome assembly	The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome.	got7fsn_ti	Wnt-LRP5/6 signalosome assembly|LRP5/6 signalosome assembly|LRP6 signalosome assembly|Wnt signalosome formation|LRP6 signalosome formation|Wnt-LRP5/6 signalosome formation|Wnt signalosome complex assembly|Wnt signalosome complex formation|LRP5/6 signalosome formation						bf	2016-01-05T15:34:36Z						biological_process											owl:Class	
GO:0090312	biolink:NamedThing	positive regulation of protein deacetylation	Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti	positive regulation of protein amino acid deacetylation						tb	2010-04-14T01:30:45Z						biological_process											owl:Class	
GO:0002710	biolink:NamedThing	negative regulation of T cell mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.	got7fsn_ti	inhibition of T cell mediated immunity|down-regulation of T cell mediated immunity|downregulation of T cell mediated immunity|negative regulation of T-lymphocyte mediated immunity|down regulation of T cell mediated immunity|negative regulation of T lymphocyte mediated immunity|negative regulation of T-cell mediated immunity													biological_process											owl:Class	
GO:0060195	biolink:NamedThing	negative regulation of antisense RNA transcription	Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.	got7fsn_ti														biological_process											owl:Class	
GO:0006080	biolink:NamedThing	substituted mannan metabolic process	The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units.	got7fsn_ti	substituted mannan metabolism													biological_process											owl:Class	
GO:0075093	biolink:NamedThing	obsolete modulation by host of symbiont signal transduction mediated by G-protein beta subunit	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0005378	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090515	biolink:NamedThing	L-glutamate transmembrane import into vacuole	The directed movement of L-glutamate into the vacuole across the vacuolar membrane.	got7fsn_ti							tb	2012-12-14T11:25:52Z						biological_process											owl:Class	
GO:0075104	biolink:NamedThing	obsolete positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0002075	biolink:NamedThing	somitomeric trunk muscle development	The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.	got7fsn_ti														biological_process											owl:Class	
GO:0034762	biolink:NamedThing	regulation of transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.	got7fsn_ti	regulation of membrane transport													biological_process											owl:Class	
GO:0045115	biolink:NamedThing	regulation of beta 2 integrin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.	got7fsn_ti	regulation of beta 2 integrin synthesis|regulation of beta 2 integrin anabolism|regulation of beta 2 integrin biosynthesis|regulation of beta 2 integrin formation													biological_process											owl:Class	
GO:0046166	biolink:NamedThing	glyceraldehyde-3-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.	got7fsn_ti	glyceraldehyde 3-phosphate biosynthetic process|glyceraldehyde-3-phosphate anabolism|glyceraldehyde-3-phosphate synthesis|glyceraldehyde 3-phosphate biosynthesis|glyceraldehyde-3-phosphate formation|glyceraldehyde-3-phosphate biosynthesis													biological_process											owl:Class	
GO:1903587	biolink:NamedThing	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.	got7fsn_ti	regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis						pga	2014-11-04T11:39:31Z						biological_process											owl:Class	
GO:0120287	biolink:NamedThing	regulation of aspartic endopeptidase activity, intramembrane cleaving	Any process that modulates the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20341					krc	2020-11-19T22:06:06Z						biological_process											owl:Class	
GO:0099044	biolink:NamedThing	vesicle tethering to endoplasmic reticulum	The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes.  Interaction can occur via direct binding  to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.	got7fsn_ti							tb	2013-01-08T15:07:50Z						biological_process											owl:Class	
GO:2001162	biolink:NamedThing	positive regulation of histone H3-K79 methylation	Any process that activates or increases the frequency, rate or extent of histone H3-K79 methylation.	got7fsn_ti	positive regulation of histone H3K79me|positive regulation of histone lysine H3 K79 methylation|positive regulation of histone H3 K79 methylation						se	2011-10-25T10:27:10Z						biological_process											owl:Class	
GO:1900269	biolink:NamedThing	negative regulation of reverse transcription	Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription.	got7fsn_ti	down-regulation of reverse transcription|down regulation of reverse transcription|downregulation of reverse transcription|inhibition of reverse transcription						tb	2012-04-03T11:13:35Z						biological_process											owl:Class	
GO:0032425	biolink:NamedThing	positive regulation of mismatch repair	Any process that activates or increases the frequency, rate or extent of mismatch repair.	got7fsn_ti	stimulation of mismatch repair|up regulation of mismatch repair|activation of mismatch repair|upregulation of mismatch repair|up-regulation of mismatch repair													biological_process											owl:Class	
GO:2000862	biolink:NamedThing	negative regulation of estrogen secretion	Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion.	got7fsn_ti	negative regulation of oestrogen secretion						bf	2011-07-26T08:48:28Z						biological_process											owl:Class	
GO:0110091	biolink:NamedThing	negative regulation of hippocampal neuron apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.	got7fsn_ti							kmv	2018-02-13T21:25:01Z						biological_process											owl:Class	
GO:1902456	biolink:NamedThing	regulation of stomatal opening	Any process that modulates the frequency, rate or extent of stomatal opening.	got7fsn_ti							tb	2013-10-16T22:25:06Z						biological_process											owl:Class	
GO:0005110	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902328	biolink:NamedThing	bacterial-type DNA replication initiation	Any DNA replication initiation that is involved in bacterial-type DNA replication.	got7fsn_ti	DNA re-replication initiation involved in bacterial-type DNA replication|DNA replication initiation involved in bacterial-type DNA replication|DNA-dependent DNA replication initiation involved in bacterial-type DNA replication|DNA endoreduplication initiation involved in bacterial-type DNA replication						jl	2013-07-25T10:48:02Z						biological_process											owl:Class	
GO:0042708	biolink:NamedThing	obsolete elastase activity	OBSOLETE. Catalysis of the hydrolysis of elastin.	got7fsn_ti	elastase activity			GO:0004175	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0100064	biolink:NamedThing	obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates filamentous growth of a population of unicellular organisms in response to starvation.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0072744	biolink:NamedThing	cellular response to trichodermin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.	got7fsn_ti							mah	2012-08-31T12:29:38Z						biological_process											owl:Class	
GO:1901104	biolink:NamedThing	tetracenomycin C metabolic process	The chemical reactions and pathways involving tetracenomycin C.	got7fsn_ti	tetracenomycin C metabolism						yaf	2012-07-11T02:50:32Z						biological_process											owl:Class	
GO:0032550	biolink:NamedThing	purine ribonucleoside binding	Binding to a purine ribonucleoside, a compound consisting of a purine base linked to ribose.	got7fsn_ti														molecular_function											owl:Class	
GO:0051076	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043746	biolink:NamedThing	obsolete N2-acetyl-L-lysine aminotransferase activity	OBSOLETE. Catalysis of the reaction: N2-acetyl-L-aminoadipate semialdehyde + L-glutamate = 2-oxoglutarate + N2-acetyl-L-lysine.	got7fsn_ti	N-acetyl-lysine aminotransferase activity	https://github.com/geneontology/go-ontology/issues/18908			This term was obsoleted because there is no evidence that it exists.					True				molecular_function											owl:Class	
GO:0002726	biolink:NamedThing	positive regulation of T cell cytokine production	Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.	got7fsn_ti	activation of T cell cytokine production|up-regulation of T cell cytokine production|stimulation of T cell cytokine production|upregulation of T cell cytokine production|positive regulation of T lymphocyte cytokine production|positive regulation of T-cell cytokine production|positive regulation of T-lymphocyte cytokine production|up regulation of T cell cytokine production													biological_process											owl:Class	
GO:0030548	biolink:NamedThing	acetylcholine receptor regulator activity	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.	got7fsn_ti														molecular_function											owl:Class	
GO:0034254	biolink:NamedThing	regulation of urea catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.	got7fsn_ti	regulation of urea degradation|regulation of urea catabolism|regulation of urea breakdown													biological_process											owl:Class	
GO:2001254	biolink:NamedThing	negative regulation of histone H3-K36 trimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K36 trimethylation.	got7fsn_ti							pr	2011-12-06T07:38:17Z						biological_process											owl:Class	
GO:0039577	biolink:NamedThing	obsolete suppression by virus of host JAK1 activity by negative regulation of JAK1 phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by stopping, preventing or reducing tyrosine phosphorylation of JAK1 and thereby activation of JAK1.	got7fsn_ti					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True				biological_process											owl:Class	
CHEBI:16973	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0110005	biolink:NamedThing	positive regulation of tRNA C5-cytosine methylation	Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation.	got7fsn_ti							kmv							biological_process											owl:Class	
GO:0051100	biolink:NamedThing	negative regulation of binding	Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.	got7fsn_ti	inhibition of binding|down-regulation of binding|downregulation of binding|down regulation of binding													biological_process											owl:Class	
CHEBI:85413	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000994	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005962	biolink:NamedThing	mitochondrial isocitrate dehydrogenase complex (NAD+)	Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity.	got7fsn_ti					Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'isocitrate dehydrogenase (NAD+) activity ; GO:0004449'.									cellular_component											owl:Class	
GO:0006372	biolink:NamedThing	obsolete lariat formation, 5'-splice site cleavage	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	lariat formation, 5'-splice site cleavage				This term was made obsolete because it represents a molecular function.	GO:0000386|GO:0000350				True				biological_process											owl:Class	
GO:0032271	biolink:NamedThing	regulation of protein polymerization	Any process that modulates the frequency, rate or extent of the process of creating protein polymers.	got7fsn_ti	regulation of protein polymerisation													biological_process											owl:Class	
GO:1901451	biolink:NamedThing	regulation of response to benzene	Any process that modulates the frequency, rate or extent of response to benzene.	got7fsn_ti							tt	2012-10-02T14:19:10Z						biological_process											owl:Class	
CHEBI:16066	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900170	biolink:NamedThing	negative regulation of glucocorticoid mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway.	got7fsn_ti	down regulation of glucocorticoid mediated signaling pathway|inhibition of glucocorticoid mediated signalling|downregulation of glucocorticoid mediated signaling pathway|inhibition of glucocorticoid mediated signaling pathway|down regulation of glucocorticoid mediated signalling|down-regulation of glucocorticoid mediated signaling pathway|downregulation of glucocorticoid mediated signalling|negative regulation of glucocorticoid mediated signalling|down-regulation of glucocorticoid mediated signalling						hjd	2012-03-08T08:33:20Z						biological_process											owl:Class	
GO:0033499	biolink:NamedThing	galactose catabolic process via UDP-galactose	The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.	got7fsn_ti	galactose breakdown via UDP-galactose|galactose degradation via UDP-galactose|Leloir Pathway|galactose catabolism via UDP-galactose											MetaCyc:PWY-3821		biological_process											owl:Class	
GO:0042102	biolink:NamedThing	positive regulation of T cell proliferation	Any process that activates or increases the rate or extent of T cell proliferation.	got7fsn_ti	stimulation of T cell proliferation|positive regulation of T lymphocyte proliferation|positive regulation of T-lymphocyte proliferation|upregulation of T cell proliferation|activation of T cell proliferation|up regulation of T cell proliferation|up-regulation of T cell proliferation													biological_process											owl:Class	
GO:0055111	biolink:NamedThing	ingression involved in gastrulation with mouth forming second	The migration of individual cells into the embryo involved in deuterostomic gastrulation.	got7fsn_ti														biological_process											owl:Class	
GO:0006389	biolink:NamedThing	obsolete tRNA-Y splicing	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	tRNA-Y splicing				This term was made obsolete because it does not represent a process unique to splicing of the tyrosyl (Y) tRNA.	GO:0006388				True				biological_process											owl:Class	
UBERON:0004786	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051584	biolink:NamedThing	regulation of dopamine uptake involved in synaptic transmission	Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.	got7fsn_ti	regulation of dopamine import involved in synaptic transmission													biological_process											owl:Class	
GO:0045315	biolink:NamedThing	positive regulation of compound eye photoreceptor development	Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.	got7fsn_ti	activation of eye photoreceptor development|upregulation of eye photoreceptor development|up regulation of eye photoreceptor development|positive regulation of eye photoreceptor development|stimulation of eye photoreceptor development|up-regulation of eye photoreceptor development													biological_process											owl:Class	
UBERON:0006172	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006969	biolink:NamedThing	obsolete melanotic tumor response	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	melanotic tumor response|melanotic mass response				This term was made obsolete because it was undefined and represented an abnormal process.					True				biological_process											owl:Class	
GO:1903803	biolink:NamedThing	L-glutamine import across plasma membrane	The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-glutamine import|L-glutamine import into cell|L-glutamine uptake						bf	2012-05-11T10:46:21Z			GO:0036229			biological_process											owl:Class	
GO:1900478	biolink:NamedThing	obsolete positive regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of sulfate assimilation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti	positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter				This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T09:08:04Z		True				biological_process											owl:Class	
UBERON:0005499	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900101	biolink:NamedThing	regulation of endoplasmic reticulum unfolded protein response	Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.	got7fsn_ti	regulation of ER unfolded protein response|regulation of erUPR|regulation of SREBP-mediated signalling pathway						ppm	2012-02-15T11:15:27Z						biological_process											owl:Class	
GO:0002704	biolink:NamedThing	negative regulation of leukocyte mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.	got7fsn_ti	negative regulation of leucocyte mediated immunity|downregulation of leukocyte mediated immunity|negative regulation of immune cell mediated immunity|down-regulation of leukocyte mediated immunity|inhibition of leukocyte mediated immunity|down regulation of leukocyte mediated immunity													biological_process											owl:Class	
GO:0036100	biolink:NamedThing	leukotriene catabolic process	The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.	got7fsn_ti	leukotriene breakdown|leukotriene catabolism|leukotriene degradation						bf	2012-01-27T01:26:24Z						biological_process											owl:Class	
GO:0048660	biolink:NamedThing	regulation of smooth muscle cell proliferation	Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.	got7fsn_ti	regulation of SMC proliferation													biological_process											owl:Class	
GO:0046779	biolink:NamedThing	obsolete suppression by virus of expression of host genes with introns	OBSOLETE. Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed.	got7fsn_ti	negative regulation by virus of expression of host genes with introns|viral inhibition of expression of host genes with introns				The reason for obsoleting this term is that it is too specific.					True				biological_process											owl:Class	
GO:1901565	biolink:NamedThing	organonitrogen compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.	got7fsn_ti	organonitrogen compound breakdown|organonitrogen compound degradation|organonitrogen compound catabolism						pr	2012-11-04T15:17:56Z						biological_process											owl:Class	
GO:1904005	biolink:NamedThing	regulation of phospholipase D activity	Any process that modulates the frequency, rate or extent of phospholipase D activity.	got7fsn_ti	regulation of choline phosphatase activity|regulation of lipophosphodiesterase II activity|regulation of lecithinase D activity|regulation of phosphatidylcholine phosphatidohydrolase activity						sl	2015-03-06T17:20:05Z						biological_process											owl:Class	
GO:0035923	biolink:NamedThing	flurbiprofen binding	Binding to flurbiprofen.	got7fsn_ti	2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid binding						bf	2011-07-15T03:53:53Z						molecular_function											owl:Class	
GO:0042840	biolink:NamedThing	D-glucuronate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.	got7fsn_ti	D-glucuronate degradation|D-glucuronate catabolism|D-glucuronate breakdown													biological_process											owl:Class	
GO:0000962	biolink:NamedThing	positive regulation of mitochondrial RNA catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.	got7fsn_ti														biological_process											owl:Class	
GO:0019315	biolink:NamedThing	D-allose biosynthetic process	The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.	got7fsn_ti	D-allose biosynthesis|D-allose formation|D-allose synthesis|D-allose anabolism													biological_process											owl:Class	
GO:0046017	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.	got7fsn_ti	mitotic regulation of transcription from Pol I promoter|regulation of transcription from Pol I promoter during mitosis|regulation of transcription from RNA polymerase I promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0006356|GO:0044772				True				biological_process											owl:Class	
GO:0061331	biolink:NamedThing	epithelial cell proliferation involved in Malpighian tubule morphogenesis	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.	got7fsn_ti							dph	2010-09-28T02:01:02Z						biological_process											owl:Class	
GO:1902125	biolink:NamedThing	(+)-pinoresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol.	got7fsn_ti	(+)-pinoresinol degradation|(+)-pinoresinol breakdown|(+)-pinoresinol catabolism						ms	2013-05-21T08:49:23Z						biological_process											owl:Class	
GO:0044043	biolink:NamedThing	obsolete multi-organism glucan metabolic process	OBSOLETE. The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, involving more than one organism.	got7fsn_ti	multi-organism glucan metabolism				This term was obsoleted because there is no evidence it exists.					True				biological_process											owl:Class	
GO:2000685	biolink:NamedThing	positive regulation of cellular response to X-ray	Any process that activates or increases the frequency, rate or extent of cellular response to X-ray.	got7fsn_ti	positive regulation of cellular response to X-ray radiation stimulus						yaf	2011-05-10T01:40:49Z						biological_process											owl:Class	
GO:0051134	biolink:NamedThing	negative regulation of NK T cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.	got7fsn_ti	negative regulation of natural T cell activation|down regulation of NK T cell activation|negative regulation of NK T-cell activation|negative regulation of NKT cell activation|downregulation of NK T cell activation|inhibition of NK T cell activation|negative regulation of natural killer T cell activation|negative regulation of NT cell activation|negative regulation of NK T-lymphocyte activation|negative regulation of NK T lymphocyte activation|down-regulation of NK T cell activation													biological_process											owl:Class	
GO:2000092	biolink:NamedThing	positive regulation of mesonephric glomerular mesangial cell proliferation	Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.	got7fsn_ti							dph	2010-09-03T06:10:33Z						biological_process											owl:Class	
GO:0075256	biolink:NamedThing	regulation of teliospore formation	Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.	got7fsn_ti														biological_process											owl:Class	
GO:1900480	biolink:NamedThing	regulation of diacylglycerol biosynthetic process	Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process.	got7fsn_ti	regulation of diacylglycerol formation|regulation of diacylglycerol synthesis|regulation of diacylglycerol biosynthesis|regulation of diacylglycerol anabolism						al	2012-05-02T10:08:59Z						biological_process											owl:Class	
CHEBI:27928	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051892	biolink:NamedThing	negative regulation of cardioblast differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti	downregulation of cardioblast differentiation|down-regulation of cardioblast differentiation|inhibition of cardioblast differentiation|down regulation of cardioblast differentiation													biological_process											owl:Class	
GO:0030464	biolink:NamedThing	obsolete aging dependent sterility (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	aging dependent sterility (sensu Fungi)				This term was made obsolete because it reflected a trait or phenotype.	GO:0030466				True				biological_process											owl:Class	
GO:0048711	biolink:NamedThing	positive regulation of astrocyte differentiation	Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.	got7fsn_ti	up-regulation of astrocyte differentiation|up regulation of astrocyte differentiation|activation of astrocyte differentiation|upregulation of astrocyte differentiation|stimulation of astrocyte differentiation													biological_process											owl:Class	
CHEBI:47622	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904662	biolink:NamedThing	positive regulation of sensory perception of bitter taste	Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste.	got7fsn_ti	up-regulation of sensory perception of bitter taste|up-regulation of bitter taste perception|up regulation of sensory perception of bitter taste|activation of sensory perception of bitter taste|up regulation of bitter taste perception|upregulation of sensory perception of bitter taste|positive regulation of bitter taste perception|activation of bitter taste perception|upregulation of bitter taste perception						mr	2015-09-04T17:54:22Z						biological_process											owl:Class	
GO:0030086	biolink:NamedThing	obsolete PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex			GO:0009655	This term was made obsolete because the 'complex' it refers to contains only one gene product.					True				cellular_component											owl:Class	
GO:1902435	biolink:NamedThing	regulation of male mating behavior	Any process that modulates the frequency, rate or extent of male mating behavior.	got7fsn_ti							mm2	2013-10-09T15:49:56Z						biological_process											owl:Class	
GO:0006927	biolink:NamedThing	obsolete transformed cell apoptotic process	OBSOLETE. Any apoptotic process in a transformed cell, a cell that has undergone changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm.	got7fsn_ti	killing transformed cells|transformed cell programmed cell death by apoptosis|apoptosis of transformed cells|transformed cell apoptosis|programmed cell death, transformed cells|programmed cell death of transformed cells by apoptosis				This term was made obsolete because it does not refer to a normal process.					True				biological_process											owl:Class	
GO:0060286	biolink:NamedThing	obsolete flagellar cell motility	OBSOLETE. Cell motility due to the motion of one or more flagella.	got7fsn_ti	flagellar cell motility				This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:0060285|GO:0071973				True				biological_process											owl:Class	
CHEBI:46645	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098892	biolink:NamedThing	extrinsic component of postsynaptic specialization membrane	The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:1904889	biolink:NamedThing	regulation of excitatory synapse assembly	Any process that modulates the frequency, rate or extent of excitatory synapse assembly.	got7fsn_ti	regulation of excitatory synapse formation						bf	2016-01-07T14:35:53Z						biological_process											owl:Class	
GO:0060767	biolink:NamedThing	epithelial cell proliferation involved in prostate gland development	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.	got7fsn_ti							dph	2009-07-08T07:32:34Z						biological_process											owl:Class	
GO:0090301	biolink:NamedThing	negative regulation of neural crest formation	Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.	got7fsn_ti							tb	2010-03-12T04:08:26Z						biological_process											owl:Class	
GO:0001901	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099093	biolink:NamedThing	calcium export from the mitochondrion	A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol.	got7fsn_ti	mitochondrial calcium release|calcium ion transmembrane export from mitochondrion|mitochondrial calcium ion export													biological_process											owl:Class	
GO:1901472	biolink:NamedThing	regulation of Golgi calcium ion export	Any process that modulates the frequency, rate or extent of Golgi calcium ion export.	got7fsn_ti							al	2012-10-03T07:26:03Z						biological_process											owl:Class	
GO:1905416	biolink:NamedThing	regulation of amoeboid sperm motility	Any process that modulates the frequency, rate or extent of amoeboid sperm motility.	got7fsn_ti	regulation of ameboid sperm motility|regulation of amoeboid sperm movement|regulation of ameboid sperm movement						pr	2016-09-01T11:28:48Z						biological_process											owl:Class	
GO:0034310	biolink:NamedThing	primary alcohol catabolic process	The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.	got7fsn_ti	primary alcohol degradation|monohydric alcohol catabolic process|primary alcohol catabolism|primary alcohol breakdown													biological_process											owl:Class	
GO:0098856	biolink:NamedThing	intestinal lipid absorption	Any process in which lipids are taken up from the contents of the intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0150132	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:63063	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051572	biolink:NamedThing	negative regulation of histone H3-K4 methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.	got7fsn_ti	down regulation of histone H3-K4 methylation|downregulation of histone H3-K4 methylation|down-regulation of histone H3-K4 methylation|inhibition of histone H3-K4 methylation													biological_process											owl:Class	
GO:0051626	biolink:NamedThing	regulation of epinephrine uptake	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell.	got7fsn_ti	regulation of adrenaline uptake|regulation of epinephrine import													biological_process											owl:Class	
GO:1904436	biolink:NamedThing	negative regulation of transferrin receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding.	got7fsn_ti	down regulation of transferrin receptor binding|down-regulation of transferrin receptor binding|downregulation of transferrin receptor binding|inhibition of transferrin receptor binding						kom	2015-07-06T13:49:07Z						biological_process											owl:Class	
GO:0072561	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904638	biolink:NamedThing	response to resveratrol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.	got7fsn_ti							sl	2015-08-31T17:07:38Z						biological_process											owl:Class	
GO:0015360	biolink:NamedThing	acetate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in).	got7fsn_ti	acetate:hydrogen symporter activity|hydrogen:acetate symporter activity										GO:0015357			molecular_function											owl:Class	
GO:0072692	biolink:NamedThing	obsolete chromatin silencing at centromere central core	OBSOLETE. Repression of transcription of DNA at the central core of a regional centromere by altering the structure of chromatin.	got7fsn_ti	centromere central core chromatin silencing|heterochromatic silencing at centromere central core|chromatin silencing at centromeric central core|chromatin silencing at chromosome kinetochore domain				This term was made obsolete because the process does not exist.		mah	2011-09-12T03:16:41Z		True				biological_process											owl:Class	
GO:0043525	biolink:NamedThing	positive regulation of neuron apoptotic process	Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.	got7fsn_ti	positive regulation of neuron apoptosis|positive regulation of programmed cell death, neurons|upregulation of neuron apoptosis|activation of neuron apoptosis|stimulation of neuron apoptosis|up regulation of neuron apoptosis|up-regulation of neuron apoptosis													biological_process											owl:Class	
GO:0006143	biolink:NamedThing	obsolete purine metabolic process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	purine metabolic process				This term was made obsolete because more appropriate terms were created.	GO:0042278|GO:0006144|GO:0006163				True				biological_process											owl:Class	
CHEBI:35280	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032566	biolink:NamedThing	dGDP binding	Binding to dGDP, deoxyguanosine diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:1902457	biolink:NamedThing	negative regulation of stomatal opening	Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening.	got7fsn_ti	down regulation of stomatal opening|down-regulation of stomatal opening|downregulation of stomatal opening|inhibition of stomatal opening						tb	2013-10-16T22:25:22Z						biological_process											owl:Class	
GO:0060632	biolink:NamedThing	regulation of microtubule-based movement	Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.	got7fsn_ti							dph	2009-05-18T03:07:02Z						biological_process											owl:Class	
GO:0004171	biolink:NamedThing	obsolete deoxyhypusine synthase activity	OBSOLETE. Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine.	got7fsn_ti	deoxyhypusine synthase activity|[eIF-5A]-deoxyhypusine synthase				This term was made obsolete because it represents a multistep reaction.	GO:0034038|GO:0008612				True				molecular_function											owl:Class	
GO:1900989	biolink:NamedThing	scopolamine metabolic process	The chemical reactions and pathways involving scopolamine.	got7fsn_ti	scopolamine metabolism						yaf	2012-06-14T09:47:38Z						biological_process											owl:Class	
GO:1902779	biolink:NamedThing	cellular response to alkane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.	got7fsn_ti							tt	2014-03-21T03:18:04Z						biological_process											owl:Class	
GO:0035358	biolink:NamedThing	regulation of peroxisome proliferator activated receptor signaling pathway	Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	got7fsn_ti	regulation of PPAR signaling pathway|regulation of peroxisome proliferator activated receptor signalling pathway|regulation of peroxisome proliferator-activated receptor signaling pathway						bf	2010-03-05T10:39:37Z						biological_process											owl:Class	
GO:0048038	biolink:NamedThing	quinone binding	Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.	got7fsn_ti														molecular_function											owl:Class	
GO:0051342	biolink:NamedThing	regulation of cyclic-nucleotide phosphodiesterase activity	Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.	got7fsn_ti	regulation of cAMP phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase regulator|regulation of cGMP phosphodiesterase activity|regulation of cyclic nucleotide phosphodiesterase activity|regulation of 3',5' cyclic nucleotide phosphodiesterase activity|phosphodiesterase regulator|regulation of 3',5'-cyclic-AMP phosphodiesterase activity|3',5' cyclic nucleotide phosphodiesterase regulator|cAMP phosphodiesterase regulator													biological_process											owl:Class	
GO:0019558	biolink:NamedThing	histidine catabolic process to 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate.	got7fsn_ti	histidine degradation to 2-oxoglutarate|histidine catabolic process to alpha-ketoglutarate|histidine catabolic process to alpha-oxoglutarate|histidine breakdown to 2-oxoglutarate|histidine catabolic process to 2-ketoglutarate|histidine catabolism to alpha-ketoglutarate|histidine catabolism to 2-ketoglutarate|histidine catabolism to alpha-oxoglutarate													biological_process											owl:Class	
GO:0071645	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 4 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.	got7fsn_ti	positive regulation of CCL4 production|positive regulation of macrophage inflammatory protein production|positive regulation of MIP-1b production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:0099035	biolink:NamedThing	anchored component of spine apparatus membrane	The component of the spine apparatus membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0048032	biolink:NamedThing	galacturonate binding	Binding to a galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	got7fsn_ti	galacturonic acid binding													molecular_function											owl:Class	
GO:0048345	biolink:NamedThing	regulation of paraxial mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.	got7fsn_ti														biological_process											owl:Class	
GO:0010120	biolink:NamedThing	camalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.	got7fsn_ti	camalexin synthesis|camalexin formation|camalexin anabolism|camalexin biosynthesis											MetaCyc:CAMALEXIN-SYN		biological_process											owl:Class	
GO:0001576	biolink:NamedThing	globoside biosynthetic process	The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).	got7fsn_ti	globoside anabolism|globoside formation|globoside biosynthesis|globoside synthesis													biological_process											owl:Class	
GO:0090244	biolink:NamedThing	Wnt signaling pathway involved in somitogenesis	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.	got7fsn_ti	Wnt-activated signaling pathway involved in somitogenesis|Wnt receptor signaling pathway involved in somitogenesis|Wnt receptor signalling						tb	2010-01-22T10:47:59Z						biological_process											owl:Class	
GO:1903218	biolink:NamedThing	regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.	got7fsn_ti	regulation of 'malic' enzyme|regulation of NADP-linked decarboxylating malic enzyme|regulation of malate dehydrogenase (decarboxylating, NADP)|regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|regulation of NADP-malic enzyme activity|regulation of NADP-specific malic enzyme|regulation of L-malate:NADP oxidoreductase activity|regulation of NADP-specific malate dehydrogenase activity|regulation of malate dehydrogenase (NADP, decarboxylating)						sart	2014-07-24T11:17:22Z						biological_process											owl:Class	
GO:0046865	biolink:NamedThing	terpenoid transport	The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups.	got7fsn_ti														biological_process											owl:Class	
UBERON:0005631	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044450	biolink:NamedThing	obsolete microtubule organizing center part	OBSOLETE. Any constituent part of a microtubule organizing center, a region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow.	got7fsn_ti	MTOC component|microtubule organizing centre component				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005815				True				cellular_component											owl:Class	
CHEBI:35227	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045968	biolink:NamedThing	negative regulation of juvenile hormone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.	got7fsn_ti	negative regulation of juvenile hormone anabolism|down regulation of juvenile hormone biosynthetic process|negative regulation of juvenile hormone biosynthesis|inhibition of juvenile hormone biosynthetic process|downregulation of juvenile hormone biosynthetic process|down-regulation of juvenile hormone biosynthetic process|negative regulation of juvenile hormone formation|negative regulation of juvenile hormone synthesis													biological_process											owl:Class	
GO:0016099	biolink:NamedThing	monoterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton.	got7fsn_ti	monoterpenoid anabolism|monoterpenoid formation|monoterpenoid synthesis|monoterpenoid biosynthesis											MetaCyc:PWY-3041		biological_process											owl:Class	
CHEBI:35352	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034331	biolink:NamedThing	cell junction maintenance	The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.	got7fsn_ti														biological_process											owl:Class	
GO:0031659	biolink:NamedThing	obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.	got7fsn_ti	G1/S-specific up regulation of cyclin-dependent protein kinase activity|G1/S-specific stimulation of cyclin-dependent protein kinase activity|G1/S-specific activation of cyclin-dependent protein kinase activity|G1/S-specific upregulation of cyclin-dependent protein kinase activity|G1/S-specific up-regulation of cyclin-dependent protein kinase activity|G1/S-specific positive regulation of cyclin-dependent protein kinase activity|positive regulation of cyclin-dependent protein kinase activity during G1/S|positive regulation of cyclin-dependent protein kinase activity involved in G1/S				The term has been obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:2000527	biolink:NamedThing	regulation of myeloid dendritic cell chemotaxis	Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.	got7fsn_ti							ebc	2011-03-23T12:18:32Z						biological_process											owl:Class	
GO:1902619	biolink:NamedThing	regulation of microtubule minus-end binding	Any process that modulates the frequency, rate or extent of microtubule minus-end binding.	got7fsn_ti							tb	2014-01-14T22:17:16Z						biological_process											owl:Class	
GO:0021907	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.	got7fsn_ti	fibroblast growth factor receptor signalling pathway in spinal cord anterior-posterior patterning													biological_process											owl:Class	
GO:1905363	biolink:NamedThing	positive regulation of endosomal vesicle fusion	Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion.	got7fsn_ti	up regulation of endosome vesicle fusion|upregulation of endosomal vesicle fusion|upregulation of endosome vesicle fusion|positive regulation of endosome vesicle fusion|up-regulation of endosome vesicle fusion|activation of endosome vesicle fusion|activation of endosomal vesicle fusion|up-regulation of endosomal vesicle fusion|up regulation of endosomal vesicle fusion						bc	2016-08-16T11:40:51Z						biological_process											owl:Class	
GO:0101013	biolink:NamedThing	mechanosensitive voltage-gated sodium channel activity	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating  together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	got7fsn_ti	mechanically-modulated voltage-gated sodium channel activity													molecular_function											owl:Class	
GO:0032194	biolink:NamedThing	ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate	The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.	got7fsn_ti														biological_process											owl:Class	
GO:0051825	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032167	biolink:NamedThing	obsolete septin patch	OBSOLETE. An amorphous-appearing accumulation of septin proteins at the future site of cytokinesis.	got7fsn_ti	septin patch				This term was made obsolete because it was added in error; it does not refer to a normal subcellular structure.					True				cellular_component											owl:Class	
GO:0006715	biolink:NamedThing	farnesol biosynthetic process	The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.	got7fsn_ti	farnesol synthesis|farnesol anabolism|farnesol biosynthesis|farnesol formation													biological_process											owl:Class	
GO:1900742	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to pH	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.	got7fsn_ti	downregulation of filamentous growth of a population of unicellular organisms in response to pH|inhibition of filamentous growth of a population of unicellular organisms in response to pH|down regulation of filamentous growth of a population of unicellular organisms in response to pH|down-regulation of filamentous growth of a population of unicellular organisms in response to pH						di	2012-05-28T02:35:03Z						biological_process											owl:Class	
GO:0051490	biolink:NamedThing	negative regulation of filopodium assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.	got7fsn_ti	downregulation of filopodium formation|negative regulation of filopodia biosynthesis|down-regulation of filopodium formation|negative regulation of filopodium formation|down regulation of filopodium formation|inhibition of filopodium formation|negative regulation of filopodia formation													biological_process											owl:Class	
GO:0062107	biolink:NamedThing	regulation of protein localization to non-growing cell tip	Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip.	got7fsn_ti							dph	2019-02-05T12:59:18Z						biological_process											owl:Class	
GO:2001200	biolink:NamedThing	positive regulation of dendritic cell differentiation	Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.	got7fsn_ti							yaf	2011-11-04T02:01:36Z						biological_process											owl:Class	
GO:0090044	biolink:NamedThing	positive regulation of tubulin deacetylation	Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.	got7fsn_ti							tb	2009-08-03T11:54:18Z						biological_process											owl:Class	
CHEBI:17087	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090056	biolink:NamedThing	regulation of chlorophyll metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll.	got7fsn_ti							tb	2009-08-07T11:47:27Z						biological_process											owl:Class	
GO:0051635	biolink:NamedThing	obsolete bacterial cell surface binding	OBSOLETE. Binding to a component on the surface of a bacterial cell.	got7fsn_ti	binding to bacterium|bacterial cell surface binding|bacterium cell surface binding|bacterial binding|bacterium binding				This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term.	GO:0042742|GO:0005102|GO:0003823				True	GO:0008367			molecular_function											owl:Class	
GO:0052362	biolink:NamedThing	obsolete catabolism by host of symbiont protein	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0001564	biolink:NamedThing	obsolete resistance to pathogenic protozoa	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	resistance to pathogenic protozoa			GO:0001562	This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0036196	biolink:NamedThing	zymosterol metabolic process	The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).	got7fsn_ti							bf	2012-04-20T10:27:06Z						biological_process											owl:Class	
CHEBI:16457	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901295	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.	got7fsn_ti	regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment						vk	2012-08-21T09:06:32Z						biological_process											owl:Class	
GO:0052267	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904100	biolink:NamedThing	positive regulation of protein O-linked glycosylation	Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation.	got7fsn_ti	activation of protein amino acid O-linked glycosylation|up regulation of protein amino acid O-linked glycosylation|upregulation of protein amino acid O-linked glycosylation|activation of protein O-linked glycosylation|up-regulation of protein amino acid O-linked glycosylation|upregulation of protein O-linked glycosylation|up regulation of protein O-linked glycosylation|positive regulation of protein amino acid O-linked glycosylation|up-regulation of protein O-linked glycosylation						krc	2015-03-27T16:10:10Z						biological_process											owl:Class	
GO:0034753	biolink:NamedThing	nuclear aryl hydrocarbon receptor complex	An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT).	got7fsn_ti	nuclear AhR complex|nuclear AHRC|6S-nuclear aryl hydrocarbon (Ah) receptor ligand-activated complex													cellular_component											owl:Class	
GO:0044802	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072543	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015515	biolink:NamedThing	citrate:succinate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).	got7fsn_ti														molecular_function											owl:Class	
GO:0000050	biolink:NamedThing	urea cycle	The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.	got7fsn_ti	ornithine cycle|urea biosynthetic process|urea biosynthesis										GO:0006871|GO:0006594	Wikipedia:Urea_cycle		biological_process											owl:Class	
GO:0055098	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905762	biolink:NamedThing	CCR4-NOT complex binding	Binding to a CCR4-NOT complex.	got7fsn_ti							mah	2016-12-15T15:48:53Z						molecular_function											owl:Class	
GO:0051195	biolink:NamedThing	obsolete negative regulation of cofactor metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.	got7fsn_ti	negative regulation of cofactor metabolism|downregulation of cofactor metabolic process|inhibition of cofactor metabolic process|down regulation of cofactor metabolic process|down-regulation of cofactor metabolic process				1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True				biological_process											owl:Class	
GO:1904902	biolink:NamedThing	ESCRT III complex assembly	The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex.	got7fsn_ti	ESCRT III complex formation						pad	2016-01-18T13:38:07Z						biological_process											owl:Class	
CHEBI:33118	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150174	biolink:NamedThing	negative regulation of phosphatidylcholine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process.	got7fsn_ti							bc	2020-01-21T14:03:53Z						biological_process											owl:Class	
CHEBI:64948	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003201	biolink:NamedThing	epithelial to mesenchymal transition involved in coronary vasculature morphogenesis	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature.	got7fsn_ti							dph	2009-10-08T01:36:54Z						biological_process											owl:Class	
GO:1900712	biolink:NamedThing	positive regulation of tensidol B biosynthetic process	Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process.	got7fsn_ti	activation of tensidol B synthesis|activation of tensidol B formation|up-regulation of tensidol B anabolism|up regulation of tensidol B biosynthetic process|upregulation of tensidol B anabolism|up-regulation of tensidol B biosynthetic process|activation of tensidol B anabolism|positive regulation of tensidol B synthesis|upregulation of tensidol B synthesis|upregulation of tensidol B biosynthetic process|up regulation of tensidol B formation|positive regulation of tensidol B biosynthesis|positive regulation of tensidol B anabolism|upregulation of tensidol B biosynthesis|up-regulation of tensidol B biosynthesis|activation of tensidol B biosynthetic process|up-regulation of tensidol B formation|up regulation of tensidol B anabolism|upregulation of tensidol B formation|activation of tensidol B biosynthesis|up-regulation of tensidol B synthesis|up regulation of tensidol B biosynthesis|positive regulation of tensidol B formation|up regulation of tensidol B synthesis						di	2012-05-22T05:03:23Z						biological_process											owl:Class	
GO:1903709	biolink:NamedThing	uterine gland development	The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure.	got7fsn_ti	endometrial gland development|glandular part of endometrium development|uterine glands set development|glandulae uterinae development|uterine glands development|set of uterine glands development|endometrium gland development						cls	2014-12-04T18:57:21Z						biological_process											owl:Class	
GO:2000645	biolink:NamedThing	negative regulation of receptor catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process.	got7fsn_ti	negative regulation of receptor degradation|negative regulation of receptor breakdown|negative regulation of receptor catabolism						vk	2011-04-21T11:20:22Z						biological_process											owl:Class	
GO:0010939	biolink:NamedThing	regulation of necrotic cell death	Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.	got7fsn_ti														biological_process											owl:Class	
GO:0015500	biolink:NamedThing	obsolete threonine/serine:sodium symporter activity	OBSOLETE. Catalysis of the reaction: (threonine or serine)(out) + Na+(out) = (threonine or serine)(in) + Na+(in).	got7fsn_ti	threonine/serine:sodium symporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0005283|GO:0015195|GO:0015194				True				molecular_function											owl:Class	
GO:0044332	biolink:NamedThing	Wnt signaling pathway involved in dorsal/ventral axis specification	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the establishment, maintenance and elaboration of the dorsal/ventral axis.	got7fsn_ti	Wnt-activated signaling pathway involved in dorsal/ventral axis specification|Wnt receptor signalling pathway involved in dorsal/ventral axis specification|Wnt receptor signaling pathway involved in dorsal/ventral axis specification						jl	2010-08-20T11:30:30Z						biological_process											owl:Class	
GO:0042665	biolink:NamedThing	regulation of ectodermal cell fate specification	Any process that mediates the specification of a cell into an ectoderm cell.	got7fsn_ti	regulation of ectoderm cell fate specification													biological_process											owl:Class	
GO:0004211	biolink:NamedThing	obsolete caspase-9 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	caspase-9 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0046186	biolink:NamedThing	acetaldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.	got7fsn_ti	acetaldehyde formation|acetaldehyde biosynthesis|acetaldehyde anabolism|acetaldehyde synthesis													biological_process											owl:Class	
GO:0010873	biolink:NamedThing	positive regulation of cholesterol esterification	Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.	got7fsn_ti														biological_process											owl:Class	
CHEBI:58280	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061466	biolink:NamedThing	obsolete plasma membrane part of cell junction	OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell junction.	got7fsn_ti					The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM.		dph	2012-10-19T13:53:44Z		True				cellular_component											owl:Class	
GO:0010392	biolink:NamedThing	galactoglucomannan metabolic process	The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units.	got7fsn_ti	galactoglucomannan metabolism													biological_process											owl:Class	
GO:0019485	biolink:NamedThing	beta-alanine catabolic process to L-alanine	The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine.	got7fsn_ti	beta-alanine breakdown to L-alanine|beta-alanine degradation to L-alanine													biological_process											owl:Class	
GO:0009460	biolink:NamedThing	obsolete cytochrome b	OBSOLETE. A cytochrome containing noncovalently bound protoheme (iron protoporphyrin IX; heme b).	got7fsn_ti	cytochrome b				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:1904061	biolink:NamedThing	positive regulation of locomotor rhythm	Any process that activates or increases the frequency, rate or extent of locomotor rhythm.	got7fsn_ti	up regulation of circadian locomotor activity rhythm|positive regulation of circadian locomotor activity rhythm|activation of locomotor rhythm|up-regulation of circadian locomotor activity rhythm|activation of circadian locomotor activity rhythm|upregulation of locomotor rhythm|up-regulation of locomotor rhythm|upregulation of circadian locomotor activity rhythm|up regulation of locomotor rhythm						sl	2015-03-18T20:39:03Z						biological_process											owl:Class	
GO:0045896	biolink:NamedThing	obsolete regulation of transcription during mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.	got7fsn_ti	regulation of transcription, mitotic|mitotic regulation of transcription	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0006357				True				biological_process											owl:Class	
GO:1905846	biolink:NamedThing	regulation of cellular response to oxidopamine	Any process that modulates the frequency, rate or extent of cellular response to oxidopamine.	got7fsn_ti							rz	2017-01-19T10:46:46Z						biological_process											owl:Class	
GO:2000849	biolink:NamedThing	regulation of glucocorticoid secretion	Any process that modulates the frequency, rate or extent of glucocorticoid secretion.	got7fsn_ti							bf	2011-07-26T08:44:43Z						biological_process											owl:Class	
GO:0002738	biolink:NamedThing	positive regulation of plasmacytoid dendritic cell cytokine production	Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.	got7fsn_ti	up regulation of plasmacytoid dendritic cell cytokine production|upregulation of plasmacytoid dendritic cell cytokine production|activation of plasmacytoid dendritic cell cytokine production|stimulation of plasmacytoid dendritic cell cytokine production|up-regulation of plasmacytoid dendritic cell cytokine production													biological_process											owl:Class	
GO:0031056	biolink:NamedThing	regulation of histone modification	Any process that modulates the frequency, rate or extent of the covalent alteration of a histone.	got7fsn_ti														biological_process											owl:Class	
GO:0098867	biolink:NamedThing	intramembranous bone growth	The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.	got7fsn_ti														biological_process											owl:Class	
GO:0071872	biolink:NamedThing	cellular response to epinephrine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.	got7fsn_ti	cellular response to adrenaline stimulus				Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.		mah	2010-09-13T03:31:40Z						biological_process											owl:Class	
GO:1905851	biolink:NamedThing	negative regulation of backward locomotion	Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion.	got7fsn_ti	down regulation of backward locomotion|downregulation of backward locomotion|inhibition of backward locomotion|down-regulation of backward locomotion						rz	2017-01-23T11:04:16Z						biological_process											owl:Class	
GO:1902827	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072694	biolink:NamedThing	obsolete cell cycle arrest in response to caffeine	OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of a caffeine stimulus.	got7fsn_ti					This term was made obsolete because it does not represent a real process.		mah	2011-12-05T01:29:00Z		True				biological_process											owl:Class	
GO:2000526	biolink:NamedThing	positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation.	got7fsn_ti	positive regulation of glycoprotein biosynthetic process of immunological synapse formation|positive regulation of glycoprotein biosynthetic process of formation of immunological synapse						ebc	2011-03-23T10:42:30Z						biological_process											owl:Class	
GO:0018950	biolink:NamedThing	o-xylene metabolic process	The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	got7fsn_ti	o-xylene metabolism|ortho-xylene metabolic process|ortho-xylene metabolism											UM-BBD_pathwayID:oxy		biological_process											owl:Class	
GO:0002851	biolink:NamedThing	positive regulation of peripheral T cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction.	got7fsn_ti	up-regulation of peripheral T cell tolerance induction|activation of peripheral T cell tolerance induction|up regulation of peripheral T cell tolerance induction|stimulation of peripheral T cell tolerance induction|upregulation of peripheral T cell tolerance induction													biological_process											owl:Class	
GO:0052351	biolink:NamedThing	obsolete induction by organism of systemic acquired resistance in symbiont	OBSOLETE. Any process in which an organism activates systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	activation by organism of systemic acquired resistance in symbiont|activation by organism of SAR in symbiont|induction by organism of systemic acquired resistance in symbiont|induction by organism of SAR in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0120094	biolink:NamedThing	negative regulation of peptidyl-lysine crotonylation	Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein.	got7fsn_ti							krc	2017-08-22T20:36:36Z						biological_process											owl:Class	
GO:1902219	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.	got7fsn_ti	down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress|inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress						rl	2013-06-13T10:19:12Z						biological_process											owl:Class	
GO:0051379	biolink:NamedThing	epinephrine binding	Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	got7fsn_ti	adrenaline binding													molecular_function											owl:Class	
GO:0005530	biolink:NamedThing	obsolete lectin	OBSOLETE. Lectins are proteins obtained particularly from the seeds of leguminous plants, but also from many other plant and animal sources, that have binding sites for specific mono or oligosaccharides in cell walls or membranes. They thereby change the physiology of the membrane to cause agglutination, mitosis, or other biochemical changes in the cell.	got7fsn_ti	lectin				This term was made obsolete because it refers to a class of gene products.	GO:0030246|GO:0007157				True				molecular_function											owl:Class	
GO:0006456	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019444	biolink:NamedThing	tryptophan catabolic process to catechol	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol.	got7fsn_ti	tryptophan breakdown to catechol|tryptophan degradation to catechol											MetaCyc:TRPCAT-PWY		biological_process											owl:Class	
GO:2000244	biolink:NamedThing	regulation of FtsZ-dependent cytokinesis	Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis.	got7fsn_ti	regulation of prokaryotic fission|regulation of prokaryote-type cytokinesis						mah	2010-11-10T02:46:36Z						biological_process											owl:Class	
GO:1904392	biolink:NamedThing	cellular response to ciliary neurotrophic factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.	got7fsn_ti							sl	2015-06-23T19:13:10Z						biological_process											owl:Class	
GO:0052568	biolink:NamedThing	obsolete response to symbiont phytoalexin production	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phytoalexins produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	response to symbiont phytoalexin production				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1901691	biolink:NamedThing	proton binding	Binding to proton.	got7fsn_ti	hydrogen ion binding						al	2012-12-07T13:50:53Z						molecular_function											owl:Class	
CHEBI:12952	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901826	biolink:NamedThing	zeaxanthin catabolic process	The chemical reactions and pathways resulting in the breakdown of zeaxanthin.	got7fsn_ti	zeaxanthin catabolism|zeaxanthin degradation|zeaxanthin breakdown						yaf	2013-01-22T11:37:00Z						biological_process											owl:Class	
GO:0052226	biolink:NamedThing	obsolete biosynthesis of substance in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism resulting in the formation of substances, where the two organisms are in a symbiotic interaction.	got7fsn_ti	biosynthesis of substance in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18787			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0015261	biolink:NamedThing	obsolete lactate channel activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	lactate channel activity				This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True				molecular_function											owl:Class	
GO:0035228	biolink:NamedThing	negative regulation of glutamate-cysteine ligase activity	Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase.	got7fsn_ti	inhibition of glutamate-cysteine ligase activity|down-regulation of glutamate-cysteine ligase activity|down regulation of glutamate-cysteine ligase activity|downregulation of glutamate-cysteine ligase activity													biological_process											owl:Class	
GO:1905702	biolink:NamedThing	regulation of inhibitory synapse assembly	Any process that modulates the frequency, rate or extent of inhibitory synapse assembly.	got7fsn_ti	regulation of inhibitory synapse formation						tb	2016-11-16T18:55:32Z						biological_process											owl:Class	
GO:0007055	biolink:NamedThing	spindle assembly involved in male meiosis II	The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.	got7fsn_ti	male meiosis II spindle assembly													biological_process											owl:Class	
GO:0046273	biolink:NamedThing	lignan catabolic process	The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.	got7fsn_ti	lignan catabolism|lignan breakdown|lignan degradation													biological_process											owl:Class	
GO:0048151	biolink:NamedThing	obsolete hyperphosphorylation	OBSOLETE. The excessive phosphorylation of a protein, as a result of activation of kinases, deactivation of phosphatases, or both.	got7fsn_ti	hyperphosphorylation			GO:0016310	This term was made obsolete because it is an unnecessary grouping term and was poorly defined.					True				biological_process											owl:Class	
GO:1903553	biolink:NamedThing	positive regulation of extracellular exosome assembly	Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.	got7fsn_ti	activation of extracellular vesicular exosome assembly|up regulation of extracellular vesicular exosome assembly|up-regulation of extracellular vesicular exosome assembly|upregulation of extracellular vesicular exosome assembly|positive regulation of extracellular vesicular exosome assembly						pga	2014-10-20T15:37:42Z						biological_process											owl:Class	
GO:0005636	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010603	biolink:NamedThing	regulation of cytoplasmic mRNA processing body assembly	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.	got7fsn_ti														biological_process											owl:Class	
GO:0034379	biolink:NamedThing	very-low-density lipoprotein particle assembly	The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle.	got7fsn_ti	VLDL assembly													biological_process											owl:Class	
GO:0031524	biolink:NamedThing	menthol metabolic process	The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.	got7fsn_ti	menthol metabolism													biological_process											owl:Class	
GO:0061392	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to osmotic stress	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12739			This term was obsoleted because it represents a GO-CAM model.	GO:0071470|GO:0006357	dph	2011-12-13T08:52:04Z		True				biological_process											owl:Class	
CHEBI:35940	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000164	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.	got7fsn_ti							dph	2010-10-05T01:06:15Z						biological_process											owl:Class	
GO:0033304	biolink:NamedThing	chlorophyll a metabolic process	The chemical reactions and pathways involving chlorophyll a.	got7fsn_ti	chlorophyll a metabolism													biological_process											owl:Class	
GO:0061136	biolink:NamedThing	regulation of proteasomal protein catabolic process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.	got7fsn_ti							dph	2010-05-17T01:33:20Z						biological_process											owl:Class	
GO:0000982	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006943	biolink:NamedThing	obsolete chemi-mechanical coupling	OBSOLETE. The conversion of chemical energy into mechanical work (as in the contraction of a muscle).	got7fsn_ti	mechanochemical coupling|chemi-mechanical coupling				This term was made obsolete because its meaning is vague, and it does not fit with other terms in GO.	GO:0009612|GO:0050954				True				biological_process											owl:Class	
GO:0010512	biolink:NamedThing	negative regulation of phosphatidylinositol biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.	got7fsn_ti														biological_process											owl:Class	
PO:0020021	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000759	biolink:NamedThing	regulation of N-terminal peptidyl-lysine acetylation	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.	got7fsn_ti							yaf	2011-06-17T12:58:16Z						biological_process											owl:Class	
GO:0075086	biolink:NamedThing	obsolete negative regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by host of symbiont transmembrane receptor-mediated cAMP signaling|inhibition by host of symbiont transmembrane receptor-mediated cAMP signal transduction|downregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0019790	biolink:NamedThing	obsolete ubiquitin-like hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ubiquitin-like hydrolase activity				This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True				molecular_function											owl:Class	
GO:2000761	biolink:NamedThing	positive regulation of N-terminal peptidyl-lysine acetylation	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.	got7fsn_ti							yaf	2011-06-17T12:58:24Z						biological_process											owl:Class	
GO:0010988	biolink:NamedThing	regulation of low-density lipoprotein particle clearance	Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							tb	2009-06-01T12:13:07Z						biological_process											owl:Class	
CHEBI:50994	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060058	biolink:NamedThing	positive regulation of apoptotic process involved in mammary gland involution	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution.	got7fsn_ti	positive regulation of apoptosis involved in mammary gland involution													biological_process											owl:Class	
GO:1903756	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:28938	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097633	biolink:NamedThing	intrinsic component of phagophore assembly site membrane	The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to phagophore assembly site membrane													cellular_component											owl:Class	
GO:1902263	biolink:NamedThing	apoptotic process involved in embryonic digit morphogenesis	Any apoptotic process that is involved in embryonic digit morphogenesis.	got7fsn_ti	apoptotic program involved in embryonic digit morphogenesis|apoptotic programmed cell death involved in embryonic digit morphogenesis|signaling (initiator) caspase activity involved in embryonic digit morphogenesis|apoptotic cell death involved in embryonic digit morphogenesis|type I programmed cell death involved in embryonic digit morphogenesis|apoptosis involved in embryonic digit morphogenesis|programmed cell death by apoptosis involved in embryonic digit morphogenesis						dph	2013-06-25T16:19:22Z						biological_process											owl:Class	
GO:0002674	biolink:NamedThing	negative regulation of acute inflammatory response	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.	got7fsn_ti	down-regulation of acute inflammatory response|down regulation of acute inflammatory response|inhibition of acute inflammatory response|downregulation of acute inflammatory response													biological_process											owl:Class	
GO:1905375	biolink:NamedThing	cellular response to homocysteine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.	got7fsn_ti	cellular response to Hcy|cellular response to 2-amino-4-mercaptobutyric acid|cellular response to 2-amino-4-sulfanylbutanoic acid						sl	2016-08-17T20:18:00Z						biological_process											owl:Class	
GO:1903861	biolink:NamedThing	positive regulation of dendrite extension	Any process that activates or increases the frequency, rate or extent of dendrite extension.	got7fsn_ti	activation of dendrite extension|up regulation of dendrite extension|up-regulation of dendrite extension|upregulation of dendrite extension				An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype.		pad	2015-02-02T15:34:09Z						biological_process											owl:Class	
GO:0035659	biolink:NamedThing	Wnt signaling pathway involved in wound healing, spreading of epidermal cells	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis.	got7fsn_ti	Wnt receptor signalling pathway involved in wound healing, spreading of epidermal cells|Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells|Wnt-activated signaling pathway involved in wound healing, spreading of epidermal cells						bf	2011-01-28T11:34:02Z						biological_process											owl:Class	
GO:2000548	biolink:NamedThing	negative regulation of dendritic cell dendrite assembly	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.	got7fsn_ti	negative regulation of dendritic extension						ebc	2011-04-03T07:22:01Z						biological_process											owl:Class	
GO:1902052	biolink:NamedThing	(25S)-Delta(7)-dafachronate binding	Binding to (25S)-Delta(7)-dafachronate.	got7fsn_ti							ab	2013-04-11T08:34:38Z						molecular_function											owl:Class	
GO:2001171	biolink:NamedThing	positive regulation of ATP biosynthetic process	Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.	got7fsn_ti	positive regulation of ATP regeneration|positive regulation of ATP synthesis|positive regulation of ATP biosynthesis|positive regulation of ATP formation|positive regulation of ATP anabolism						kmv	2011-10-26T03:18:26Z						biological_process											owl:Class	
GO:0062078	biolink:NamedThing	TSC1-TSC2 complex binding	Binding to a TSC1-TSC2 complex.	got7fsn_ti	tuberin sclerosis complex binding|tuberin-hamartin complex binding						dph	2018-10-11T12:31:42Z						molecular_function											owl:Class	
GO:1903661	biolink:NamedThing	positive regulation of complement-dependent cytotoxicity	Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity.	got7fsn_ti	up-regulation of complement-dependent cytotoxicity|upregulation of complement-dependent cytotoxicity|activation of complement-dependent cytotoxicity|up regulation of complement-dependent cytotoxicity						jl	2014-11-25T15:04:11Z						biological_process											owl:Class	
GO:0006692	biolink:NamedThing	prostanoid metabolic process	The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.	got7fsn_ti	prostanoid metabolism													biological_process											owl:Class	
CHEBI:57922	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007057	biolink:NamedThing	spindle assembly involved in female meiosis I	The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.	got7fsn_ti	female meiosis I spindle assembly													biological_process											owl:Class	
GO:1903366	biolink:NamedThing	negative regulation of fear response	Any process that stops, prevents or reduces the frequency, rate or extent of fear response.	got7fsn_ti	down regulation of fear response|inhibition of fear response|down-regulation of physiological fear response|inhibition of physiological fear response|down regulation of physiological fear response|down-regulation of fear response|downregulation of physiological fear response|downregulation of fear response|negative regulation of physiological fear response						mr	2014-08-21T23:21:45Z						biological_process											owl:Class	
GO:0051872	biolink:NamedThing	sphingosine catabolic process	The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.	got7fsn_ti	(4E)-sphing-4-enine catabolic process|sphing-4-enine catabolism|(4E)-sphing-4-enine catabolism|sphing-4-enine catabolic process													biological_process											owl:Class	
GO:0045881	biolink:NamedThing	positive regulation of sporulation resulting in formation of a cellular spore	Any process that activates or increases the frequency, rate or extent of sporulation.	got7fsn_ti	up-regulation of sporulation|up regulation of sporulation|upregulation of sporulation|activation of sporulation|stimulation of sporulation													biological_process											owl:Class	
GO:0098539	biolink:NamedThing	cytoplasmic side of transport vesicle membrane	The side (leaflet) of the transport vesicle membrane that faces the cytoplasm.	got7fsn_ti	external side of transport vesicle membrane						dos	2013-10-24T11:48:07Z						cellular_component											owl:Class	
GO:0001883	biolink:NamedThing	purine nucleoside binding	Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.	got7fsn_ti														molecular_function											owl:Class	
GO:0099518	biolink:NamedThing	vesicle cytoskeletal trafficking	The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.	got7fsn_ti	vesicle cytoskeletal transport|cytoskeletal fiber-based vesicle localization													biological_process											owl:Class	
GO:0006689	biolink:NamedThing	ganglioside catabolic process	The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.	got7fsn_ti	ganglioside catabolism|ganglioside breakdown|ganglioside degradation													biological_process											owl:Class	
GO:0060191	biolink:NamedThing	regulation of lipase activity	Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.	got7fsn_ti														biological_process											owl:Class	
GO:1901518	biolink:NamedThing	aspyridone A biosynthetic process	The chemical reactions and pathways resulting in the formation of aspyridone A.	got7fsn_ti	aspyridone A anabolism|aspyridone A biosynthesis|aspyridone A synthesis|aspyridone A formation						di	2012-10-18T18:31:36Z						biological_process											owl:Class	
GO:0033341	biolink:NamedThing	regulation of collagen binding	Any process that modulates the frequency, rate or extent of collagen binding.	got7fsn_ti														biological_process											owl:Class	
GO:1903574	biolink:NamedThing	negative regulation of cellular response to amino acid starvation	Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation.	got7fsn_ti	downregulation of cellular response to amino acid starvation|inhibition of cellular response to amino acid starvation|down-regulation of cellular response to amino acid starvation|down regulation of cellular response to amino acid starvation						bf	2014-10-27T16:21:02Z						biological_process											owl:Class	
GO:0051341	biolink:NamedThing	regulation of oxidoreductase activity	Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.	got7fsn_ti	oxidoreductase regulator													biological_process											owl:Class	
GO:0006987	biolink:NamedThing	obsolete activation of signaling protein activity involved in unfolded protein response	OBSOLETE. The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response.	got7fsn_ti	unfolded protein response, activation of signalling protein kinase/endonuclease|unfolded protein response, activation of signaling protein activity|unfolded protein response, activation of signaling protein kinase/endonuclease				The reason for obsoletion is that this process represents a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498).	GO:0036498				True				biological_process											owl:Class	
GO:0036305	biolink:NamedThing	ameloblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.	got7fsn_ti							bf	2012-08-08T13:49:15Z						biological_process											owl:Class	
GO:1905707	biolink:NamedThing	negative regulation of mitochondrial ATP synthesis coupled proton transport	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.	got7fsn_ti							vw	2016-11-17T14:07:40Z						biological_process											owl:Class	
GO:0031557	biolink:NamedThing	obsolete induction of programmed cell death in response to chemical stimulus	OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus.	got7fsn_ti	induction of programmed cell death in response to chemical substance|induction of programmed cell death in response to chemical stimulus				This term was made obsolete because it is now superseded by better defined and more specific terms under the node of GO:0012501 programmed cell death.					True				biological_process											owl:Class	
GO:0010502	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090045	biolink:NamedThing	positive regulation of deacetylase activity	Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.	got7fsn_ti							tb	2009-08-03T12:00:14Z						biological_process											owl:Class	
GO:1900518	biolink:NamedThing	regulation of response to pullulan	Any process that modulates the frequency, rate or extent of response to pullulan.	got7fsn_ti							tt	2012-05-02T04:11:58Z						biological_process											owl:Class	
GO:0010774	biolink:NamedThing	meiotic strand invasion involved in reciprocal meiotic recombination	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti														biological_process											owl:Class	
GO:1905543	biolink:NamedThing	interleukin-15 receptor complex	A protein complex that binds interleukin-15 (IL-15) and that consists of, at a minimum, an interleukin, an alpha, beta and gamma chain as well as optional additional kinase subunits. The alpha chain is unique to binds IL-15 while it shares the beta chain with the IL-2 receptor and the cytokine receptor common gamma chain with multiple interleukin receptors.	got7fsn_ti	IL15 receptor complex|IL15-receptor complex|IL-15-receptor complex|interleukin-15-receptor complex|IL-15 receptor complex				An example of this is IL15RA in human (Q13261) in PMID:23104097 (inferred from physical interaction).		bhm	2016-10-10T13:38:12Z						cellular_component											owl:Class	
GO:1903320	biolink:NamedThing	regulation of protein modification by small protein conjugation or removal	Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal.	got7fsn_ti							vw	2014-08-18T13:01:00Z						biological_process											owl:Class	
GO:0044052	biolink:NamedThing	obsolete interaction with host via substance released by membrane budding	OBSOLETE. An interaction with the host organism mediated by a substance released via symbiont membrane budding, the evagination of a membrane resulting in formation of a vesicle.	got7fsn_ti	interaction with host via substance released by symbiont membrane budding				This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True				biological_process											owl:Class	
GO:2001109	biolink:NamedThing	regulation of lens epithelial cell proliferation	Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation.	got7fsn_ti							yaf	2011-09-30T02:04:53Z						biological_process											owl:Class	
GO:1903760	biolink:NamedThing	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.	got7fsn_ti	regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential						rl	2014-12-19T12:01:59Z						biological_process											owl:Class	
GO:0106071	biolink:NamedThing	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.	got7fsn_ti	positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway						hjd	2017-11-28T18:38:52Z						biological_process											owl:Class	
GO:1903520	biolink:NamedThing	negative regulation of mammary gland involution	Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution.	got7fsn_ti	inhibition of mammary gland involution|downregulation of mammary gland involution|down regulation of mammary gland involution|down-regulation of mammary gland involution						dph	2014-10-06T12:01:30Z						biological_process											owl:Class	
GO:2001225	biolink:NamedThing	regulation of chloride transport	Any process that modulates the frequency, rate or extent of chloride transport.	got7fsn_ti							dph	2011-11-18T05:45:56Z						biological_process											owl:Class	
GO:0071510	biolink:NamedThing	obsolete activation of MAPKKK activity involved in conjugation with cellular fusion	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of conjugation with cellular fusion.	got7fsn_ti	activation of MAPKKK activity involved in mating response|activation of MAP kinase kinase kinase activity during conjugation with cellular fusion|conjugation with cellular fusion, activation of MAP kinase kinase kinase activity|conjugation with cellular fusion, activation of MAPKKK activity	https://github.com/geneontology/go-ontology/issues/20242			This term was obsoleted because it represents a GO-CAM model.		mah	2010-01-05T02:10:18Z		True				biological_process											owl:Class	
GO:0044124	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905064	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.	got7fsn_ti	down regulation of vascular associated smooth muscle cell differentiation|negative regulation of vascular smooth muscle cell differentiation|downregulation of vascular smooth muscle cell differentiation|down-regulation of vascular associated smooth muscle cell differentiation|inhibition of vascular associated smooth muscle cell differentiation|down-regulation of vascular smooth muscle cell differentiation|down regulation of VSMC differentiation|down regulation of vascular smooth muscle cell differentiation|downregulation of VSMC differentiation|inhibition of VSMC differentiation|inhibition of vascular smooth muscle cell differentiation|downregulation of vascular associated smooth muscle cell differentiation|down-regulation of VSMC differentiation|negative regulation of VSMC differentiation						rph	2016-03-21T11:15:03Z						biological_process											owl:Class	
UBERON:0005325	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005926	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000005663	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046668	biolink:NamedThing	regulation of retinal cell programmed cell death	Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.	got7fsn_ti	regulation of retinal programmed cell death													biological_process											owl:Class	
GO:0032363	biolink:NamedThing	FMN catabolic process	The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.	got7fsn_ti														biological_process											owl:Class	
CHEBI:57926	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002911	biolink:NamedThing	regulation of lymphocyte anergy	Any process that modulates the frequency, rate, or extent of lymphocyte anergy.	got7fsn_ti														biological_process											owl:Class	
GO:0008197	biolink:NamedThing	obsolete yolk protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	yolk protein				This term was made obsolete because it does not represent a molecular function.	GO:0005198|GO:0045735				True				molecular_function											owl:Class	
GO:0009500	biolink:NamedThing	obsolete dicluster bacterial-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	dicluster bacterial-type ferredoxin			GO:0009055	This term was made obsolete because it does not represent a function.					True				molecular_function											owl:Class	
GO:1901884	biolink:NamedThing	4-hydroxycoumarin biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin.	got7fsn_ti	4-hydroxycoumarin formation|4-hydroxycoumarin anabolism|4-hydroxycoumarin biosynthesis|4-hydroxycoumarin synthesis						ms	2013-02-06T14:05:59Z						biological_process											owl:Class	
GO:1902208	biolink:NamedThing	regulation of bacterial-type flagellum assembly	Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly.	got7fsn_ti	regulation of bacterial flagellum assembly						jl	2013-06-11T14:20:19Z						biological_process											owl:Class	
GO:0008711	biolink:NamedThing	obsolete ADP-L-glycero-D-manno-heptose synthase activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	ADP-L-glycero-D-manno-heptose synthase activity				This term was made obsolete because it represents a bifunctional gene product (e.g. E. coli RfaE).	GO:0033785|GO:0033786				True				molecular_function											owl:Class	
GO:0032385	biolink:NamedThing	positive regulation of intracellular cholesterol transport	Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.	got7fsn_ti	upregulation of intracellular cholesterol transport|up regulation of intracellular cholesterol transport|stimulation of intracellular cholesterol transport|up-regulation of intracellular cholesterol transport|activation of intracellular cholesterol transport													biological_process											owl:Class	
GO:0005924	biolink:NamedThing	obsolete cell-substrate adherens junction	OBSOLETE. An adherens junction which connects a cell to the extracellular matrix.	got7fsn_ti	hemi-adherens junction				The reason for obsoletion is that, based on the most recent literature, there is no such structure in biology as 'cell-substrate adherens junction'. An 'adherens junction' is always a 'cell-cell junction' (PMIDs: 20571587, 17854762, 21422226, 28096264, 28401269, 26923917).					True				cellular_component											owl:Class	
GO:1901461	biolink:NamedThing	negative regulation of response to formic acid	Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid.	got7fsn_ti	down regulation of response to formic acid|down-regulation of response to formic acid|downregulation of response to formic acid|inhibition of response to formic acid						tt	2012-10-02T14:29:02Z						biological_process											owl:Class	
GO:0006331	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000190	biolink:NamedThing	obsolete negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor.	got7fsn_ti	negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor				This term was made obsolete because it makes no sense and was added in error.	GO:0030522|GO:0030374|GO:0004879|GO:0000122	rl	2010-10-18T10:02:57Z		True				biological_process											owl:Class	
GO:0099028	biolink:NamedThing	anchored component of postynaptic endocytic zone membrane	The component of the postynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0048380	biolink:NamedThing	negative regulation of lateral mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification.	got7fsn_ti	inhibition of lateral mesodermal cell fate specification|downregulation of lateral mesodermal cell fate specification|down-regulation of lateral mesodermal cell fate specification|down regulation of lateral mesodermal cell fate specification|negative regulation of lateral plate mesodermal cell fate specification													biological_process											owl:Class	
GO:0031368	biolink:NamedThing	obsolete Pro-X metallocarboxypeptidase activity	OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a metallopeptidase mechanism to release a C-terminal amino acid.	got7fsn_ti	carboxypeptidase P activity|Pro-X metallocarboxypeptidase activity|membrane Pro-X carboxypeptidase activity|membrane Pro-Xaa carboxypeptidase|microsomal carboxypeptidase activity				This term was made obsolete because it represents a gene product.	GO:0004181|GO:0008233				True		EC:3.4.17.16		molecular_function											owl:Class	
CHEBI:51078	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045643	biolink:NamedThing	regulation of eosinophil differentiation	Any process that modulates the frequency, rate or extent of eosinophil differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0090339	biolink:NamedThing	negative regulation of formin-nucleated actin cable assembly	Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.	got7fsn_ti							tb	2010-06-01T03:26:31Z						biological_process											owl:Class	
GO:0039632	biolink:NamedThing	RNA translocase activity involved in viral RNA genome packaging	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule, which contributes to the packaging of viral RNA into a nucleocapsid.	got7fsn_ti	RNA packaging ATPase activity|viral RNA packaging activity						bf	2012-08-07T11:20:53Z						molecular_function											owl:Class	
GO:2000980	biolink:NamedThing	regulation of inner ear receptor cell differentiation	Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation.	got7fsn_ti	regulation of inner ear hair cell differentiation						yaf	2011-08-03T02:38:43Z						biological_process											owl:Class	
CHEBI:26391	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046047	biolink:NamedThing	TTP catabolic process	The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate.	got7fsn_ti	TTP breakdown|TTP degradation|TTP hydrolysis|TTP catabolism													biological_process											owl:Class	
GO:1903022	biolink:NamedThing	positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.	got7fsn_ti	activation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|up-regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|upregulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|up regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands						tb	2014-05-14T23:44:47Z						biological_process											owl:Class	
GO:0030459	biolink:NamedThing	obsolete inactivation of MAPK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	inactivation of MAPK (mating sensu Fungi)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0000821	biolink:NamedThing	regulation of arginine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.	got7fsn_ti	regulation of arginine metabolism													biological_process											owl:Class	
GO:0030465	biolink:NamedThing	obsolete autophagic death (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	autophagic death (sensu Fungi)				This term was made obsolete because a more correct term has been created.	GO:0048102				True				biological_process											owl:Class	
GO:1905718	biolink:NamedThing	obsolete mitotic spindle astral microtubule end	OBSOLETE. Any microtubule end that is part of a mitotic spindle astral microtubule.	got7fsn_ti	mitotic spindle astral microtubule tip				This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2016-11-24T14:30:11Z		True				cellular_component											owl:Class	
GO:0046346	biolink:NamedThing	mannosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.	got7fsn_ti	mannosamine breakdown|mannosamine degradation|mannosamine catabolism													biological_process											owl:Class	
PR:000001192	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099011	biolink:NamedThing	neuronal dense core vesicle exocytosis	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels.	got7fsn_ti							kmv							biological_process											owl:Class	
GO:1902134	biolink:NamedThing	(+)-secoisolariciresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol.	got7fsn_ti	(+)-secoisolariciresinol degradation|(+)-secoisolariciresinol catabolism|(+)-secoisolariciresinol breakdown						ms	2013-05-21T08:50:09Z						biological_process											owl:Class	
GO:1900728	biolink:NamedThing	cardiac neural crest cell delamination involved in outflow tract morphogenesis	Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis.	got7fsn_ti							bf	2012-05-25T09:50:24Z						biological_process											owl:Class	
GO:1905675	biolink:NamedThing	negative regulation of adaptive immune memory response	Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.	got7fsn_ti	down regulation of adaptive immune memory response|downregulation of adaptive immune memory response|down-regulation of adaptive immune memory response|inhibition of adaptive immune memory response						tb	2016-11-11T22:24:41Z						biological_process											owl:Class	
UBERON:0000019	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000097	biolink:NamedThing	regulation of smooth muscle cell-matrix adhesion	Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion.	got7fsn_ti							dph	2010-09-14T04:22:20Z						biological_process											owl:Class	
GO:0052171	biolink:NamedThing	obsolete growth or development during symbiotic interaction	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.	got7fsn_ti	growth or development during symbiotic interaction				This term was made obsolete because it contained a conjunction (or).	GO:0044111				True				biological_process											owl:Class	
GO:0086085	biolink:NamedThing	cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication	Binding to a protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells.	got7fsn_ti	cell adhesive protein binding involved in SA cardiomyocyte-atrial cardiomyocyte communication						dph	2011-11-22T11:15:07Z						molecular_function											owl:Class	
GO:2000782	biolink:NamedThing	regulation of establishment of cell polarity regulating cell shape	Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape.	got7fsn_ti							mah	2011-06-23T12:17:38Z						biological_process											owl:Class	
GO:0052210	biolink:NamedThing	obsolete interaction with other organism via protein secreted by type III secretion system involved in symbiotic interaction	OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type III secretion system, where the two organisms are in a symbiotic interaction.	got7fsn_ti	interaction with other organism via protein secreted by type III secretion system during symbiotic interaction				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
GO:1901674	biolink:NamedThing	regulation of histone H3-K27 acetylation	Any process that modulates the frequency, rate or extent of histone H3-K27 acetylation.	got7fsn_ti	regulation of histone H3K27 acetylation|regulation of histone H3 acetylation at K27						vk	2012-11-22T12:06:31Z						biological_process											owl:Class	
GO:0048064	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008370	biolink:NamedThing	obsolete cellular component	OBSOLETE. These are terms that have been removed from the active component ontology.	got7fsn_ti					This term was made obsolete because it is unnecessary in the OBO flat file format.					True				cellular_component											owl:Class	
GO:0019623	biolink:NamedThing	atrazine catabolic process to urea	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea.	got7fsn_ti	atrazine degradation to urea|atrazine breakdown to urea													biological_process											owl:Class	
GO:2001289	biolink:NamedThing	lipid X metabolic process	The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate.	got7fsn_ti	2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolic process|2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolic process|2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolism|2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolic process|lipid X metabolism|Lipid X metabolic process|2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolism|Lipid X metabolism|2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolism						tb	2012-01-13T11:28:58Z						biological_process											owl:Class	
GO:0075333	biolink:NamedThing	obsolete positive regulation by host of symbiont adenylate cyclase-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0003434	biolink:NamedThing	BMP signaling pathway involved in growth plate cartilage chondrocyte development	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of a growth plate cartilage chondrocyte over time.	got7fsn_ti	BMP signalling pathway involved in growth plate cartilage chondrocyte development						dph	2009-12-22T12:50:17Z						biological_process											owl:Class	
GO:1904009	biolink:NamedThing	cellular response to monosodium glutamate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus.	got7fsn_ti							sl	2015-03-06T18:26:40Z						biological_process											owl:Class	
GO:0033237	biolink:NamedThing	obsolete 11-beta-hydroxysteroid dehydrogenase (NADP+) activity	OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.	got7fsn_ti	11beta-hydroxysteroid:NADP+ 11-oxidoreductase|beta-hydroxysteroid dehydrogenase|11-beta-hydroxysteroid dehydrogenase (NADP+) activity|corticosteroid 11-beta-dehydrogenase activity			GO:0070524						True				molecular_function											owl:Class	
GO:1900533	biolink:NamedThing	palmitic acid metabolic process	The chemical reactions and pathways involving palmitic acid.	got7fsn_ti							tb	2012-05-09T07:03:55Z						biological_process											owl:Class	
GO:2000133	biolink:NamedThing	positive regulation of tyramine signaling pathway	Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway.	got7fsn_ti	positive regulation of tyramine signalling pathway						mah	2010-09-29T09:32:03Z						biological_process											owl:Class	
GO:0106070	biolink:NamedThing	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.	got7fsn_ti	regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway						hjd	2017-11-28T18:28:22Z						biological_process											owl:Class	
GO:0050945	biolink:NamedThing	positive regulation of iridophore differentiation	Any process that activates or increases the frequency, rate or extent of iridophore differentiation.	got7fsn_ti	upregulation of iridophore differentiation|stimulation of iridophore differentiation|up-regulation of iridophore differentiation|up regulation of iridophore differentiation|activation of iridophore differentiation													biological_process											owl:Class	
UBERON:0004737	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004246	biolink:NamedThing	obsolete peptidyl-dipeptidase A activity	OBSOLETE. Catalysis of the release of a C-terminal dipeptide, Xaa-Xbb from oligopeptide-Xaa-Xbb, when Xaa is not Pro, and Xbb is neither Asp nor Glu. Converts angiotensin I to angiotensin II.	got7fsn_ti	peptidyldipeptide hydrolase activity|ACE activity|kininase II activity|peptidyl-dipeptidase A activity|PDH|angiotensin converting enzyme|peptidyl-dipeptide hydrolase activity|peptidyl dipeptide hydrolase activity|peptidase P activity|dipeptide hydrolase|carboxycathepsin activity|peptidyl dipeptidase A|DCP|peptidyl dipeptidase-4|angiotensin I-converting enzyme activity|endothelial cell peptidyl dipeptidase activity|dipeptidyl carboxypeptidase I activity|peptidyl dipeptidase I activity				This term was made obsolete because it represents a gene product.	GO:0008237|GO:0008241				True		MetaCyc:3.4.15.1-RXN|EC:3.4.15.1		molecular_function											owl:Class	
GO:0062237	biolink:NamedThing	protein localization to postsynapse	Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.	got7fsn_ti							dph	2020-04-20T13:58:43Z						biological_process											owl:Class	
GO:0071414	biolink:NamedThing	cellular response to methotrexate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.	got7fsn_ti							mah	2009-12-14T03:10:30Z						biological_process											owl:Class	
CHEBI:61346	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097425	biolink:NamedThing	obsolete smooth endoplasmic reticulum part	OBSOLETE. Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER).	got7fsn_ti	SER subcomponent				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005790	pr	2012-11-07T13:45:14Z		True		NIF_Subcellular:sao184202831		cellular_component											owl:Class	
GO:0032900	biolink:NamedThing	negative regulation of neurotrophin production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin.	got7fsn_ti	down regulation of neurotrophin production|inhibition of neurotrophin production|down-regulation of neurotrophin production|downregulation of neurotrophin production													biological_process											owl:Class	
GO:0070396	biolink:NamedThing	lipoteichoic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	got7fsn_ti	lipoteichoic acid catabolism|lipoteichoic acid degradation|lipoteichoic acid breakdown													biological_process											owl:Class	
GO:1902190	biolink:NamedThing	2-methylbutanoyl-CoA(4-) catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-).	got7fsn_ti	2-methylbutanoyl-CoA(4-) degradation|2-methylbutanoyl-CoA(4-) breakdown|2-methylbutanoyl-CoA(4-) catabolism						ms	2013-06-06T09:40:20Z						biological_process											owl:Class	
GO:0010874	biolink:NamedThing	regulation of cholesterol efflux	Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.	got7fsn_ti														biological_process											owl:Class	
GO:0016834	biolink:NamedThing	obsolete other carbon-carbon lyase activity	OBSOLETE. A grouping term for carbon-carbon lyases that cannot be more accurately categorized.	got7fsn_ti	other carbon-carbon lyase activity				This term was made obsolete because it was an unnecessary grouping term.	GO:0016830				True				molecular_function											owl:Class	
GO:0098889	biolink:NamedThing	intrinsic component of presynaptic membrane	The component of the presynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to presynaptic membrane													cellular_component											owl:Class	
GO:1905475	biolink:NamedThing	regulation of protein localization to membrane	Any process that modulates the frequency, rate or extent of protein localization to membrane.	got7fsn_ti	regulation of protein localisation in membrane|regulation of protein localization in membrane						bc	2016-09-21T16:20:03Z						biological_process											owl:Class	
GO:1901061	biolink:NamedThing	guaiacyl lignin metabolic process	The chemical reactions and pathways involving guaiacyl lignin.	got7fsn_ti	G-lignin metabolic process|guaiacyl lignin metabolism						tt	2012-06-29T02:46:39Z						biological_process											owl:Class	
GO:1904401	biolink:NamedThing	cellular response to Thyroid stimulating hormone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.	got7fsn_ti							sl	2015-06-23T20:57:59Z						biological_process											owl:Class	
GO:0033586	biolink:NamedThing	L-phenylalanine biosynthetic process from chorismate via L-arogenate	The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate.	got7fsn_ti	L-phenylalanine biosynthesis from chorismate via L-arogenate|L-phenylalanine synthesis from chorismate via L-arogenate|L-phenylalanine anabolism from chorismate via L-arogenate|L-phenylalanine formation from chorismate via L-arogenate											MetaCyc:PWY-3462		biological_process											owl:Class	
GO:0075154	biolink:NamedThing	obsolete positive regulation of transmembrane receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:2000051	biolink:NamedThing	negative regulation of non-canonical Wnt signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway.	got7fsn_ti	negative regulation of non-canonical Wnt receptor signaling pathway|negative regulation of non-canonical Wnt-activated signaling pathway|negative regulation of beta-catenin-independent Wnt receptor signaling pathway|negative regulation of non-canonical Wnt receptor signalling pathway						jl	2010-08-20T01:04:20Z						biological_process											owl:Class	
GO:0006197	biolink:NamedThing	obsolete adenylate deaminase reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	adenylate deaminase reaction			GO:0003876	This term was made obsolete because it represents a molecular function.					True				biological_process											owl:Class	
GO:1905071	biolink:NamedThing	tight junction disassembly	The disaggregation of an tight junction into its constituent components.	got7fsn_ti	occluding cell junction disassembly|occluding junction disassembly						rl	2016-03-23T12:35:08Z						biological_process											owl:Class	
UBERON:0005203	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900420	biolink:NamedThing	negative regulation of cellular alcohol catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process.	got7fsn_ti	down-regulation of cellular alcohol catabolic process|downregulation of cellular alcohol catabolic process|inhibition of cellular alcohol catabolic process|down regulation of cellular alcohol catabolic process						krc	2012-04-20T10:21:28Z						biological_process											owl:Class	
GO:0032064	biolink:NamedThing	positive regulation of translational initiation in response to osmotic stress	Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti	up-regulation of translation initiation in response to osmotic stress|upregulation of translation initiation in response to osmotic stress|activation of translation initiation in response to osmotic stress|stimulation of translation initiation in response to osmotic stress|up regulation of translation initiation in response to osmotic stress													biological_process											owl:Class	
GO:2000177	biolink:NamedThing	regulation of neural precursor cell proliferation	Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.	got7fsn_ti							dph	2010-10-13T12:40:41Z						biological_process											owl:Class	
GO:0030617	biolink:NamedThing	obsolete transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity	OBSOLETE. A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators.	got7fsn_ti	TGF-beta receptor, inhibitory cytoplasmic mediator activity|inhibitory SMAD protein|TGFbeta receptor, inhibitory cytoplasmic mediator activity	https://github.com/geneontology/go-ontology/issues/16202			This term was obsoleted because it represents the same activity as GO:0140416 ; DNA-binding transcription factor inhibitor activity', occurs_in cytosol.	GO:0140416				True				molecular_function											owl:Class	
GO:0045634	biolink:NamedThing	regulation of melanocyte differentiation	Any process that modulates the frequency, rate or extent of melanocyte differentiation.	got7fsn_ti	regulation of melanophore differentiation													biological_process											owl:Class	
GO:0062175	biolink:NamedThing	brexanolone catabolic process	The chemical reactions and pathways resulting in the breakdown of brexanolone.	got7fsn_ti	brexanolone catabolism|allotetrahydroprogesterone breakdown|brexanolone degradation|allotetrahydroprogesterone catabolic process|allopregnanolone catabolic process|allopregnanolone catabolism|allopregnanolone breakdown|allopregnanolone degradation|allotetrahydroprogesterone degradation|brexanolone breakdown|allotetrahydroprogesterone catabolism						dph	2019-11-18T19:57:46Z						biological_process											owl:Class	
GO:1904358	biolink:NamedThing	positive regulation of telomere maintenance via telomere lengthening	Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.	got7fsn_ti	activation of telomere maintenance via telomere lengthening|up regulation of telomere maintenance via telomere lengthening|upregulation of telomere maintenance via telomere lengthening|up-regulation of telomere maintenance via telomere lengthening						nc	2015-06-12T16:53:28Z						biological_process											owl:Class	
GO:1990556	biolink:NamedThing	mitochondrial isopropylmalate transmembrane transport	The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:47:11Z						biological_process											owl:Class	
GO:0075298	biolink:NamedThing	regulation of zygospore formation	Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.	got7fsn_ti														biological_process											owl:Class	
GO:0010871	biolink:NamedThing	obsolete negative regulation of receptor biosynthetic process	OBSOLETE. Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
UBERON:0001723	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034194	biolink:NamedThing	D-galactonate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid.	got7fsn_ti	D-galactonate catabolism|D-galactonate breakdown|D-galactonate degradation											MetaCyc:GALACTCAT-PWY		biological_process											owl:Class	
GO:0045715	biolink:NamedThing	obsolete negative regulation of low-density lipoprotein particle receptor biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.	got7fsn_ti	negative regulation of low-density lipoprotein receptor synthesis|inhibition of low-density lipoprotein receptor biosynthetic process|down-regulation of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor biosynthetic process|down regulation of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor formation|negative regulation of low-density lipoprotein receptor biosynthesis|negative regulation of low-density lipoprotein receptor anabolism|downregulation of low-density lipoprotein receptor biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0010908	biolink:NamedThing	regulation of heparan sulfate proteoglycan biosynthetic process	Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.	got7fsn_ti														biological_process											owl:Class	
UBERON:0002081	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990132	biolink:NamedThing	obsolete release of misfolded protein from chaperone	OBSOLETE. The release of misfolded proteins that are being held by the chaperone heat shock protein (Hsp) and targeting them for destruction by the Ub-proteasome machinery.	got7fsn_ti	release of misfolded protein from chaperone				This term was obsoleted at the TermGenie Gatekeeper stage.		rb	2013-06-25T21:56:37Z		True				biological_process											owl:Class	
GO:1901122	biolink:NamedThing	bacitracin A metabolic process	The chemical reactions and pathways involving bacitracin A.	got7fsn_ti	bacitracin A metabolism						yaf	2012-07-11T03:15:56Z						biological_process											owl:Class	
GO:0045530	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060467	biolink:NamedThing	negative regulation of fertilization	Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).	got7fsn_ti														biological_process											owl:Class	
GO:1901108	biolink:NamedThing	granaticin catabolic process	The chemical reactions and pathways resulting in the breakdown of granaticin.	got7fsn_ti	granaticin degradation|granaticin breakdown|granaticin catabolism						yaf	2012-07-11T02:51:33Z						biological_process											owl:Class	
CHEBI:19062	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16567	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003842	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120173	biolink:NamedThing	regulation of actin filament bundle convergence involved in mitotic contractile ring assembly	Any process that modulates the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly.	got7fsn_ti							krc	2018-05-31T18:08:01Z						biological_process											owl:Class	
GO:1902014	biolink:NamedThing	poly(glycerol phosphate) teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid.	got7fsn_ti	poly(glycerol phosphate) teichoic acid synthesis|poly(glycerol phosphate) teichoic acid biosynthesis|poly(glycerol phosphate) teichoic acid anabolism|poly(glycerol phosphate) teichoic acid formation						tb	2013-03-22T15:43:50Z						biological_process											owl:Class	
GO:0009808	biolink:NamedThing	lignin metabolic process	The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units.	got7fsn_ti	lignin metabolism													biological_process											owl:Class	
GO:0031614	biolink:NamedThing	obsolete ER proteasome regulatory particle, lid subcomplex	OBSOLETE. The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the endoplasmic reticulum of a cell.	got7fsn_ti					This term was made obsolete because there is no evidence in the literature of its existence.					True				cellular_component											owl:Class	
GO:0120315	biolink:NamedThing	positive regulation of oocyte karyosome formation	Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21298					krc	2021-04-19T21:49:35Z						biological_process											owl:Class	
GO:0075311	biolink:NamedThing	positive regulation of sporangium development	Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.	got7fsn_ti														biological_process											owl:Class	
GO:0002863	biolink:NamedThing	positive regulation of inflammatory response to antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.	got7fsn_ti	up-regulation of inflammatory response to antigenic stimulus|upregulation of inflammatory response to antigenic stimulus|up regulation of inflammatory response to antigenic stimulus|stimulation of inflammatory response to antigenic stimulus|activation of inflammatory response to antigenic stimulus													biological_process											owl:Class	
UBERON:0001714	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000808	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000056	biolink:NamedThing	regulation of Wnt signaling pathway involved in digestive tract morphogenesis	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.	got7fsn_ti	regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis|regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis|regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis						jl	2010-08-20T01:17:27Z						biological_process											owl:Class	
GO:0043418	biolink:NamedThing	homocysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.	got7fsn_ti	homocysteine degradation|homocysteine breakdown|homocysteine catabolism													biological_process											owl:Class	
CHEBI:27601	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025541	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905736	biolink:NamedThing	negative regulation of L-proline import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane.	got7fsn_ti							vw	2016-12-04T20:42:24Z						biological_process											owl:Class	
GO:0046228	biolink:NamedThing	2,4,5-trichlorophenoxyacetic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.	got7fsn_ti	2,4,5-trichlorophenoxyacetic acid breakdown|2,4,5-trichlorophenoxyacetic acid catabolism|2,4,5-trichlorophenoxyacetic acid degradation													biological_process											owl:Class	
GO:2000681	biolink:NamedThing	obsolete negative regulation of rubidium ion transport	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transport.	got7fsn_ti	negative regulation of rubidium cation transport|negative regulation of Rb+ transport				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-10T10:54:34Z		True				biological_process											owl:Class	
GO:0060825	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate.	got7fsn_ti	fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation						dph	2009-08-11T01:40:03Z						biological_process											owl:Class	
GO:1904114	biolink:NamedThing	positive regulation of muscle filament sliding	Any process that activates or increases the frequency, rate or extent of muscle filament sliding.	got7fsn_ti	activation of muscle filament sliding|up-regulation of muscle filament sliding|upregulation of muscle filament sliding|up regulation of muscle filament sliding						kmv	2015-04-03T18:40:44Z						biological_process											owl:Class	
CHEBI:5445	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001219	biolink:NamedThing	obsolete positive regulation of S/G2 transition of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of S/G2 transition of mitotic cell cycle.	got7fsn_ti	positive regulation of S/G2 transition of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.		dph	2011-11-16T09:14:50Z		True				biological_process											owl:Class	
GO:0042196	biolink:NamedThing	chlorinated hydrocarbon metabolic process	The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.	got7fsn_ti	chlorinated hydrocarbon metabolism													biological_process											owl:Class	
GO:1990553	biolink:NamedThing	mitochondrial 5'-adenylyl sulfate transmembrane transport	The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:32:01Z						biological_process											owl:Class	
GO:0036251	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to salt stress	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/12739			This term was obsoleted because it represents a GO-CAM model.	GO:0045944|GO:0071472	bf	2012-06-12T11:38:22Z		True				biological_process											owl:Class	
GO:0005074	biolink:NamedThing	obsolete inhibitory SMAD protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	inhibitory SMAD protein				This term was made obsolete because it names a family of gene products.					True				molecular_function											owl:Class	
GO:1903511	biolink:NamedThing	orotic acid metabolic process	The chemical reactions and pathways involving orotic acid.	got7fsn_ti	orotic acid metabolism						dph	2014-10-01T21:58:06Z						biological_process											owl:Class	
GO:0033271	biolink:NamedThing	myo-inositol phosphate transport	The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0043612	biolink:NamedThing	isoprene biosynthetic process	The chemical reactions and pathways resulting in the formation of isoprene, C5H8.	got7fsn_ti	hemiterpene biosynthesis|2-methyl-1,3-butadiene biosynthetic process|hemiterpene biosynthetic process|2-methyl-1,3-butadiene biosynthesis													biological_process											owl:Class	
GO:1905256	biolink:NamedThing	negative regulation of RNA binding transcription factor activity	Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity.	got7fsn_ti	down regulation of RNA binding transcription factor activity|downregulation of RNA binding transcription factor activity|down-regulation of RNA binding transcription factor activity|inhibition of RNA binding transcription factor activity						bf	2016-06-13T11:29:20Z						biological_process											owl:Class	
GO:0015392	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046758	biolink:NamedThing	obsolete lytic virus budding from Golgi membrane	OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host Golgi membrane system, resulting in envelopment of the virus and cell lysis.	got7fsn_ti	lytic virus budding from Golgi membrane|lytic viral budding from Golgi membrane|lytic Golgi membrane viral budding				This term was made obsolete because it does not appear to correspond to a real biological process.					True				biological_process											owl:Class	
GO:2001068	biolink:NamedThing	arabinoxylan binding	Binding to arabinoxylan.	got7fsn_ti							jl	2011-09-14T11:58:38Z						molecular_function											owl:Class	
GO:1903072	biolink:NamedThing	regulation of death-inducing signaling complex assembly	Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly.	got7fsn_ti	regulation of DISC assembly|regulation of death-inducing signaling complex formation|regulation of DD-mediated complex assembly|regulation of death-inducing signalling complex assembly|regulation of death domain-mediated complex assembly|regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|regulation of DISC formation						bf	2014-05-29T09:33:13Z						biological_process											owl:Class	
GO:0089707	biolink:NamedThing	L-lysine transmembrane export from vacuole	The directed movement of L-lysine out of the vacuole, across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0015493	biolink:NamedThing	lysine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in).	got7fsn_ti	lysine:hydrogen symporter activity													molecular_function											owl:Class	
PR:000006933	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002335	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000796	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010836	biolink:NamedThing	negative regulation of protein ADP-ribosylation	Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.	got7fsn_ti	negative regulation of protein amino acid ADP-ribosylation													biological_process											owl:Class	
GO:0034488	biolink:NamedThing	basic amino acid transmembrane export from vacuole	The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0071412	biolink:NamedThing	cellular response to genistein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.	got7fsn_ti							mah	2009-12-14T03:10:04Z						biological_process											owl:Class	
GO:0070510	biolink:NamedThing	regulation of histone H4-K20 methylation	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.	got7fsn_ti														biological_process											owl:Class	
GO:1901917	biolink:NamedThing	regulation of exoribonuclease activity	Any process that modulates the frequency, rate or extent of exoribonuclease activity.	got7fsn_ti							rb	2013-02-15T00:57:56Z						biological_process											owl:Class	
GO:0071624	biolink:NamedThing	positive regulation of granulocyte chemotaxis	Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.	got7fsn_ti							mah	2010-02-09T04:15:36Z						biological_process											owl:Class	
GO:1902681	biolink:NamedThing	regulation of replication fork arrest at rDNA repeats	Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.	got7fsn_ti	regulation of replication fork arrest at ribosomal DNA repeats|regulation of replication fork blocking at rDNA repeats						mah	2014-02-05T16:59:21Z						biological_process											owl:Class	
GO:2000804	biolink:NamedThing	regulation of termination of RNA polymerase II transcription, poly(A)-coupled	Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.	got7fsn_ti	regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|regulation of transcription termination from Pol II promoter, poly(A) coupled|regulation of termination of RNA polymerase II transcription, polyadenylation-coupled						pr	2011-07-04T08:41:27Z						biological_process											owl:Class	
GO:0043357	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046141	biolink:NamedThing	corrin catabolic process	The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.	got7fsn_ti	corrin degradation|corrin breakdown|corrin catabolism													biological_process											owl:Class	
CHEBI:17824	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045356	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033986	biolink:NamedThing	response to methanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0003798	biolink:NamedThing	obsolete male-specific antibacterial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells, but which is only expressed in males.	got7fsn_ti	male-specific antibacterial peptide activity				This term was made obsolete because it describes involvement in a process and not a function.	GO:0050831				True				molecular_function											owl:Class	
GO:0003375	biolink:NamedThing	regulation of dynamin family protein polymerization involved in membrane fission	Any process that modulates the rate, frequency, or extent of dynamin family protein polymerization involved in mitochondrial fission.	got7fsn_ti							dph	2009-12-09T05:50:15Z						biological_process											owl:Class	
GO:0046264	biolink:NamedThing	obsolete thiocyanate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of thiocyanate, any anion or salt of thiocyanic acid.	got7fsn_ti	thiocyanate synthesis|thiocyanate biosynthesis|thiocyanate formation|thiocyanate anabolism|thiocyanate biosynthetic process			GO:0018969	This term was made obsolete because thiocyanates are not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0045770	biolink:NamedThing	positive regulation of asymmetric cell division	Any process that activates or increases the frequency, rate or extent of asymmetric cell division.	got7fsn_ti	up regulation of asymmetric cell division|activation of asymmetric cell division|upregulation of asymmetric cell division|stimulation of asymmetric cell division|up-regulation of asymmetric cell division													biological_process											owl:Class	
CHEBI:50715	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990022	biolink:NamedThing	obsolete RNA polymerase III complex import into nucleus	OBSOLETE. The directed movement of an RNA polymerase III complex from the cytoplasm to the nucleus.	got7fsn_ti	RNA polymerase III complex localisation to nucleus|DNA-directed RNA polymerase III complex localization to nucleus|RNA polymerase III complex import into nucleus|RNA polymerase III complex localization to nucleus|DNA-directed RNA polymerase III complex import into nucleus				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606	pr	2013-01-15T12:46:26Z		True				biological_process											owl:Class	
GO:0060160	biolink:NamedThing	negative regulation of dopamine receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.	got7fsn_ti	negative regulation of dopamine receptor signalling pathway													biological_process											owl:Class	
GO:0035428	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OIO:hasNarrowSynonym	biolink:NamedThing	has_narrow_synonym		got7fsn_ti																									owl:AnnotationProperty	
GO:0099167	biolink:NamedThing	integral component of postsynaptic specialization membrane of symmetric synapse	The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti							dos	2017-09-10T11:58:46Z						cellular_component											owl:Class	
GO:1904124	biolink:NamedThing	microglial cell migration	The orderly movement of a microglial cell from one site to another.	got7fsn_ti							nc	2015-04-10T16:04:49Z						biological_process											owl:Class	
GO:1904559	biolink:NamedThing	cellular response to dextromethorphan	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.	got7fsn_ti							mr	2015-08-14T16:09:24Z						biological_process											owl:Class	
CHEBI:63062	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904542	biolink:NamedThing	regulation of free ubiquitin chain polymerization	Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization.	got7fsn_ti					An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype).		pad	2015-08-11T11:44:53Z						biological_process											owl:Class	
GO:0046357	biolink:NamedThing	galactarate biosynthetic process	The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid.	got7fsn_ti	galactarate formation|D-galactarate synthesis|D-galactarate anabolism|D-galactarate biosynthesis|D-galactarate biosynthetic process|D-galactarate formation|galactarate biosynthesis|galactarate anabolism|galactarate synthesis										GO:0042872			biological_process											owl:Class	
GO:0003706	biolink:NamedThing	obsolete ligand-regulated transcription factor activity	OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II in response to a ligand.	got7fsn_ti	ligand-regulated transcription factor activity				This term was made obsolete because it does not convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism.	GO:0004879|GO:0030374				True				molecular_function											owl:Class	
GO:1901010	biolink:NamedThing	(S)-reticuline metabolic process	The chemical reactions and pathways involving (S)-reticuline.	got7fsn_ti	(S)-reticuline metabolism						yaf	2012-06-15T10:46:22Z						biological_process											owl:Class	
GO:0044064	biolink:NamedThing	modulation by symbiont of host respiratory system process	The alteration by a symbiont organism of the functioning of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.	got7fsn_ti	regulation by symbiont of host respiratory system process													biological_process											owl:Class	
GO:0061081	biolink:NamedThing	positive regulation of myeloid leukocyte cytokine production involved in immune response	Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.	got7fsn_ti	positive regulation of myeloid cell cytokine production involved in immune response						dph	2010-04-13T11:26:41Z						biological_process											owl:Class	
GO:1902751	biolink:NamedThing	positive regulation of cell cycle G2/M phase transition	Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.	got7fsn_ti	up regulation of cell cycle G2/M phase transition|activation of cell cycle G2/M phase transition|upregulation of cell cycle G2/M phase transition|up-regulation of cell cycle G2/M phase transition						jl	2014-03-05T15:38:27Z						biological_process											owl:Class	
GO:1904307	biolink:NamedThing	response to desipramine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.	got7fsn_ti							sl	2015-06-10T17:00:31Z						biological_process											owl:Class	
CHEBI:139069	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071647	biolink:NamedThing	negative regulation of macrophage inflammatory protein-1 gamma production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.	got7fsn_ti	negative regulation of MIP-1g production|negative regulation of CCL9 production|negative regulation of chemokine (C-C motif) ligand 9 production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:0014740	biolink:NamedThing	negative regulation of muscle hyperplasia	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia.	got7fsn_ti														biological_process											owl:Class	
GO:1904067	biolink:NamedThing	ascr#2 binding	Binding to ascr#2.	got7fsn_ti							kmv	2015-03-20T01:39:04Z						molecular_function											owl:Class	
GO:1903928	biolink:NamedThing	cellular response to cyanide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.	got7fsn_ti							sl	2015-02-11T19:04:28Z						biological_process											owl:Class	
GO:1900878	biolink:NamedThing	(Z)-nonadeca-1,14-diene metabolic process	The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene.	got7fsn_ti	(Z)-nonadeca-1,14-diene metabolism						tt	2012-06-13T02:09:18Z						biological_process											owl:Class	
GO:0034478	biolink:NamedThing	phosphatidylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.	got7fsn_ti	phosphatidylglycerol catabolism|phosphatidylglycerol breakdown|phosphatidylglycerol degradation													biological_process											owl:Class	
GO:0000039	biolink:NamedThing	obsolete plasma membrane long-chain fatty acid transporter	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	plasma membrane long-chain fatty acid transporter				This term was made obsolete because it describes a gene product and it contains component information.	GO:0005324|GO:0005886				True				molecular_function											owl:Class	
GO:1905211	biolink:NamedThing	negative regulation of fibroblast chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis.	got7fsn_ti	down-regulation of fibroblast chemotaxis|downregulation of fibroblast chemotaxis|inhibition of fibroblast chemotaxis|down regulation of fibroblast chemotaxis						sl	2016-06-02T20:08:51Z						biological_process											owl:Class	
CHEBI:17632	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902811	biolink:NamedThing	positive regulation of skeletal muscle fiber differentiation	Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.	got7fsn_ti	activation of skeletal muscle fiber differentiation|upregulation of skeletal muscle fiber differentiation|up-regulation of skeletal muscle fiber differentiation|up regulation of skeletal muscle fiber differentiation						mr	2014-03-26T21:18:38Z						biological_process											owl:Class	
UBERON:0004190	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150038	biolink:NamedThing	postsynaptic dense core vesicle exocytosis	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels.	got7fsn_ti							bc	2018-04-18T14:32:16Z						biological_process											owl:Class	
GO:0035012	biolink:NamedThing	obsolete polytene chromosome, telomeric region	OBSOLETE. The terminal region of a polytene chromosome.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19177			This term was obsoleted because it likely represents an assay for GO:0099115 chromosome, subtelomeric region.					True				cellular_component											owl:Class	
GO:0015070	biolink:NamedThing	obsolete toxin activity	OBSOLETE. Acts as to cause injury to other living organisms.	got7fsn_ti	toxin activity				This term was made obsolete because it represents a classification of molecules and not a molecular function.	GO:0090729				True				molecular_function											owl:Class	
GO:2000338	biolink:NamedThing	regulation of chemokine (C-X-C motif) ligand 1 production	Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.	got7fsn_ti	regulation of KC production|regulation of keratinocyte derived chemokine production|regulation of SCYB1 production|regulation of CXCL1 production						mah	2011-02-01T10:46:27Z						biological_process											owl:Class	
GO:0005477	biolink:NamedThing	pyruvate secondary active transmembrane transporter activity	Enables the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	got7fsn_ti	pyruvate carrier activity													molecular_function											owl:Class	
GO:0007153	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005613	biolink:NamedThing	obsolete laminin receptor protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	laminin receptor protein				This term was made obsolete because it is out of date. It seems to be referring to the non-integrin 34/67kDa laminin receptor, which new research has shown to actually be a ribosomal protein of the SP2 family.	GO:0008305				True				cellular_component											owl:Class	
GO:0097430	biolink:NamedThing	copper ion import across prospore membrane	The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol.	got7fsn_ti	copper ion import across prospore membrane|copper ion transport into forespores|copper ion import into ascospore-type prospore						pr	2012-11-16T12:37:05Z						biological_process											owl:Class	
CHEBI:16583	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016033	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032939	biolink:NamedThing	positive regulation of translation in response to oxidative stress	Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	got7fsn_ti	activation of translation in response to oxidative stress|up regulation of translation in response to oxidative stress|stimulation of translation in response to oxidative stress|up-regulation of translation in response to oxidative stress|upregulation of translation in response to oxidative stress													biological_process											owl:Class	
CHEBI:57451	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000277	biolink:NamedThing	positive regulation of oxidative phosphorylation uncoupler activity	Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity.	got7fsn_ti	positive regulation of uncoupling protein activity|positive regulation of mitochondrial uncoupling protein activity						mah	2010-12-07T12:15:02Z						biological_process											owl:Class	
GO:2001089	biolink:NamedThing	maltotriose transport	The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T01:24:26Z						biological_process											owl:Class	
GO:0018248	biolink:NamedThing	obsolete enzyme active site formation via peptidyl cysteine sulfation	OBSOLETE. The formation of an enzyme active site via transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.	got7fsn_ti	enzyme active site formation via S-sulpho-L-cysteine	https://github.com/geneontology/go-ontology/issues/15594			This term was obsoleted because it was created by error: cysteine sulfation is a post-translational modification, see PMID:12876326.					True				biological_process											owl:Class	
GO:0006343	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0010005	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034346	biolink:NamedThing	positive regulation of type III interferon production	Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.	got7fsn_ti	positive regulation of type III IFN production|up-regulation of type III interferon production|upregulation of type III interferon production|stimulation of type III interferon production|up regulation of type III interferon production|activation of type III interferon production				Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.									biological_process											owl:Class	
GO:0015675	biolink:NamedThing	nickel cation transport	The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0070803	biolink:NamedThing	negative regulation of metula development	Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.	got7fsn_ti							mah	2009-07-08T04:38:04Z						biological_process											owl:Class	
GO:0005572	biolink:NamedThing	obsolete RNA polymerase II transcribed untranslated RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	RNA polymerase II transcribed untranslated RNA				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0015729	biolink:NamedThing	oxaloacetate transport	The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0004213	biolink:NamedThing	obsolete cathepsin B activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.	got7fsn_ti	cathepsin B1 activity|cathepsin II|cathepsin B activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0106192	biolink:NamedThing	obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate	OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T16:52:54Z		True				molecular_function											owl:Class	
GO:0002671	biolink:NamedThing	negative regulation of B cell anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy.	got7fsn_ti	downregulation of B cell anergy|down-regulation of B cell anergy|down regulation of B cell anergy|negative regulation of B-lymphocyte anergy|negative regulation of B lymphocyte anergy|negative regulation of B-cell anergy|inhibition of B cell anergy													biological_process											owl:Class	
GO:0000216	biolink:NamedThing	obsolete M/G1 transition of mitotic cell cycle	OBSOLETE. Progression from M phase to G1 phase of the mitotic cell cycle.	got7fsn_ti	M/G1 transition of mitotic cell cycle				This term was made obsolete because it does not refer to a real biological process.					True				biological_process											owl:Class	
GO:0019744	biolink:NamedThing	hopanoid metabolic process	The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.	got7fsn_ti	hopanoid metabolism													biological_process											owl:Class	
GO:0010792	biolink:NamedThing	DNA double-strand break processing involved in repair via single-strand annealing	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.	got7fsn_ti														biological_process											owl:Class	
GO:0002197	biolink:NamedThing	xanthine dehydrogenase complex	A homodimeric protein complex having xanthine dehydrogenase activity.	got7fsn_ti							hjd	2011-10-03T03:55:57Z						cellular_component											owl:Class	
GO:0017082	biolink:NamedThing	obsolete mineralocorticoid receptor activity	OBSOLETE. Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by binding to a specific DNA sequence in order to modulate transcription by RNA polymerase II.	got7fsn_ti	aldosterone receptor	https://github.com/geneontology/go-ontology/issues/16732								True				molecular_function											owl:Class	
PR:000001123	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009152	biolink:NamedThing	purine ribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine ribonucleotide biosynthesis|purine ribonucleotide synthesis|purine ribonucleotide formation|purine ribonucleotide anabolism													biological_process											owl:Class	
GO:1901068	biolink:NamedThing	guanosine-containing compound metabolic process	The chemical reactions and pathways involving guanosine-containing compounds (guanosines).	got7fsn_ti	guanosine-containing compound metabolism|guanosines metabolic process|guanosines metabolism						bf	2012-07-02T01:51:37Z						biological_process											owl:Class	
GO:1902243	biolink:NamedThing	copal-8-ol diphosphate(3-) biosynthetic process	The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-).	got7fsn_ti	copal-8-ol diphosphate(3-) formation|copal-8-ol diphosphate(3-) anabolism|copal-8-ol diphosphate(3-) biosynthesis|copal-8-ol diphosphate(3-) synthesis						ms	2013-06-20T09:09:38Z						biological_process											owl:Class	
GO:0008132	biolink:NamedThing	obsolete pancreatic elastase activity	OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin.	got7fsn_ti	pancreatic elastase activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0048503	biolink:NamedThing	obsolete GPI anchor binding	OBSOLETE. Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.	got7fsn_ti	GPI anchor binding|glycosylphosphatidylinositol binding				This term was made obsolete because it has been widely, and incorrectly, used to annotate proteins that have GPI anchors covalently attached. A new term has been created that can be used to annotate gene products that interact non-covalently with GPI anchors.					True				molecular_function											owl:Class	
GO:0110166	biolink:NamedThing	DNA synthesis involved in mitochondrial DNA replication	Any DNA biosynthetic process that is involved in mitochondrial DNA replication.	got7fsn_ti	DNA biosynthetic process involved in mitochondrial DNA replication	https://github.com/geneontology/go-ontology/issues/17716					kmv	2020-03-18T13:30:39Z						biological_process											owl:Class	
GO:2001148	biolink:NamedThing	regulation of dipeptide transmembrane transport	Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport.	got7fsn_ti	regulation of dipeptide membrane transport						kmv	2011-10-21T04:34:20Z						biological_process											owl:Class	
GO:0098898	biolink:NamedThing	dense core granule lumen	The volume enclosed by the dense core granule membrane.	got7fsn_ti	dense core vesicle lumen													cellular_component											owl:Class	
GO:1900449	biolink:NamedThing	regulation of glutamate receptor signaling pathway	Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway.	got7fsn_ti	regulation of glutamate signaling pathway|regulation of glutamate signalling pathway						rl	2012-04-27T03:45:43Z						biological_process											owl:Class	
CHEBI:64616	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001122	biolink:NamedThing	maltoheptaose metabolic process	The chemical reactions and pathways involving a maltoheptaose.	got7fsn_ti	maltoheptaose metabolism						jl	2011-10-11T02:41:26Z						biological_process											owl:Class	
GO:0052283	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018920	biolink:NamedThing	glyphosate metabolic process	The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond.	got7fsn_ti	Roundup metabolism|glyphosate metabolism|Roundup metabolic process											UM-BBD_pathwayID:gly		biological_process											owl:Class	
CHEBI:18859	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010746	biolink:NamedThing	regulation of long-chain fatty acid import across plasma membrane	Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	got7fsn_ti	regulation of plasma membrane long-chain fatty acid transport													biological_process											owl:Class	
GO:0072722	biolink:NamedThing	response to amitrole	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.	got7fsn_ti	response to 3-amino-1,2,4-triazole						mah	2012-05-31T10:51:45Z						biological_process											owl:Class	
CHEBI:64622	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905843	biolink:NamedThing	regulation of cellular response to gamma radiation	Any process that modulates the frequency, rate or extent of cellular response to gamma radiation.	got7fsn_ti	regulation of cellular response to gamma-ray photon|regulation of cellular response to gamma ray						rz	2017-01-19T10:24:39Z						biological_process											owl:Class	
UBERON:0002513	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0036042	biolink:NamedThing	long-chain fatty acyl-CoA binding	Binding to a long-chain fatty acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.	got7fsn_ti	long-chain fatty acyl-coenyme A binding	https://github.com/geneontology/go-ontology/issues/19443					bf	2011-11-24T04:31:09Z						molecular_function											owl:Class	
GO:1901777	biolink:NamedThing	mitomycin C biosynthetic process	The chemical reactions and pathways resulting in the formation of mitomycin C.	got7fsn_ti	mitomycin C formation|mitomycin C biosynthesis|mitomycin C anabolism|mitomycin C synthesis						yaf	2013-01-15T12:11:57Z						biological_process											owl:Class	
GO:0031107	biolink:NamedThing	septin ring disassembly	The controlled breakdown of a septin ring.	got7fsn_ti														biological_process											owl:Class	
GO:0099013	biolink:NamedThing	neuronal dense core vesicle lumen	The volume enclosed by a neuronal dense core vesicle membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0009499	biolink:NamedThing	obsolete monocluster bacterial-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	monocluster bacterial-type ferredoxin			GO:0009055	This term was made obsolete because it does not represent a function.					True				molecular_function											owl:Class	
GO:2000040	biolink:NamedThing	regulation of planar cell polarity pathway involved in axis elongation	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.	got7fsn_ti							dph	2010-08-18T02:47:49Z						biological_process											owl:Class	
GO:1904260	biolink:NamedThing	negative regulation of basement membrane assembly involved in embryonic body morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.	got7fsn_ti	down regulation of basement membrane assembly involved in embryonic body morphogenesis|inhibition of basement membrane assembly involved in embryonic body morphogenesis|down-regulation of basement membrane assembly involved in embryonic body morphogenesis|downregulation of basement membrane assembly involved in embryonic body morphogenesis						als	2015-05-21T09:20:49Z						biological_process											owl:Class	
CHEBI:35615	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28199	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901804	biolink:NamedThing	beta-glucoside metabolic process	The chemical reactions and pathways involving beta-glucoside.	got7fsn_ti	beta-glucoside metabolism						yaf	2013-01-22T10:10:21Z						biological_process											owl:Class	
GO:0008145	biolink:NamedThing	phenylalkylamine binding	Binding to phenylalkylamine or one of its derivatives.	got7fsn_ti														molecular_function											owl:Class	
GO:0090413	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process	OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process.	got7fsn_ti	negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process					GO:0000122	tb	2011-09-01T03:10:41Z		True				biological_process											owl:Class	
GO:0034334	biolink:NamedThing	adherens junction maintenance	The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	got7fsn_ti														biological_process											owl:Class	
GO:2001238	biolink:NamedThing	positive regulation of extrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.	got7fsn_ti	positive regulation of extrinsic apoptosis|positive regulation of extrinsic apoptotic signalling pathway						pr	2011-11-24T01:30:16Z						biological_process											owl:Class	
GO:0106215	biolink:NamedThing	negative regulation of vesicle fusion with Golgi apparatus	Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus.	got7fsn_ti							hjd	2019-06-27T15:17:17Z						biological_process											owl:Class	
GO:0015674	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090152	biolink:NamedThing	establishment of protein localization to mitochondrial membrane involved in mitochondrial fission	The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission.	got7fsn_ti	establishment of protein localisation in mitochondrial membrane involved in mitochondrial fission|establishment of protein localization in mitochondrial membrane involved in mitochondrial fission						tb	2009-12-08T03:18:51Z						biological_process											owl:Class	
GO:0090291	biolink:NamedThing	negative regulation of osteoclast proliferation	Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.	got7fsn_ti							tb	2010-02-18T03:11:03Z						biological_process											owl:Class	
GO:0010709	biolink:NamedThing	heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences.	got7fsn_ti														biological_process											owl:Class	
GO:0006126	biolink:NamedThing	obsolete other pathways of electron transport	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	other pathways of electron transport			GO:0022900	This term was made obsolete because it was an unnecessary grouping term.					True				biological_process											owl:Class	
GO:0100017	biolink:NamedThing	obsolete negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates single organismal cell-cell adhesion.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:1904975	biolink:NamedThing	response to bleomycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.	got7fsn_ti							mah	2016-02-18T15:21:23Z						biological_process											owl:Class	
GO:1901647	biolink:NamedThing	positive regulation of synoviocyte proliferation	Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation.	got7fsn_ti	upregulation of synoviocyte proliferation|up-regulation of synoviocyte proliferation|activation of synoviocyte proliferation|up regulation of synoviocyte proliferation						hjd	2012-11-16T20:16:32Z						biological_process											owl:Class	
GO:1903722	biolink:NamedThing	regulation of centriole elongation	Any process that modulates the frequency, rate or extent of centriole elongation.	got7fsn_ti							als	2014-12-09T16:36:02Z						biological_process											owl:Class	
GO:0050993	biolink:NamedThing	dimethylallyl diphosphate metabolic process	The chemical reactions and pathways involving dimethylallyl diphosphate.	got7fsn_ti	DPP metabolism|DPP metabolic process|dimethylallyl pyrophosphate metabolic process|dimethylallyl pyrophosphate metabolism|dimethylallyl diphosphate metabolism													biological_process											owl:Class	
GO:0046882	biolink:NamedThing	negative regulation of follicle-stimulating hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.	got7fsn_ti	down regulation of follicle-stimulating hormone secretion|inhibition of follicle-stimulating hormone secretion|negative regulation of follicle stimulating hormone secretion|down-regulation of follicle-stimulating hormone secretion|downregulation of follicle-stimulating hormone secretion													biological_process											owl:Class	
GO:0000072	biolink:NamedThing	obsolete M phase specific microtubule process	OBSOLETE. A microtubule-based process that occurs only during M phase of the cell cycle.	got7fsn_ti	M-phase specific microtubule process|M phase specific microtubule process				This term was made obsolete because terms already exist for centrosome/spindle organization which would be more suitable for the existing annotations, and the phase could be captured as an annotation extension if necessary.	GO:0007017				True				biological_process											owl:Class	
GO:1900986	biolink:NamedThing	ajmaline metabolic process	The chemical reactions and pathways involving ajmaline.	got7fsn_ti	ajmaline metabolism						yaf	2012-06-14T09:47:02Z						biological_process											owl:Class	
GO:0046949	biolink:NamedThing	fatty-acyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.	got7fsn_ti	fatty-acyl-CoA biosynthesis|fatty acyl CoA biosynthetic process|fatty-acyl-CoA synthesis|fatty-acyl-CoA anabolism|fatty-acyl-CoA formation													biological_process											owl:Class	
GO:1901482	biolink:NamedThing	L-lysine import into vacuole involved in cellular response to nitrogen starvation	A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation.	got7fsn_ti							al	2012-10-08T08:34:03Z						biological_process											owl:Class	
GO:0075065	biolink:NamedThing	obsolete growth or development of symbiont in host cell	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	growth or development of symbiont in host cell				This term was made obsolete because it contained a conjunction (or).					True				biological_process											owl:Class	
UBERON:0002894	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902238	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.	got7fsn_ti							pr	2013-06-19T14:00:34Z						biological_process											owl:Class	
GO:0033082	biolink:NamedThing	regulation of extrathymic T cell differentiation	Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation.	got7fsn_ti	regulation of extrathymic T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:2000740	biolink:NamedThing	negative regulation of mesenchymal stem cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation.	got7fsn_ti							yaf	2011-06-14T02:31:31Z						biological_process											owl:Class	
GO:1904050	biolink:NamedThing	positive regulation of spontaneous neurotransmitter secretion	Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion.	got7fsn_ti	upregulation of spontaneous neurotransmitter secretion|positive regulation of stimulus-independent neurotransmitter secretion|up regulation of stimulus-independent neurotransmitter secretion|activation of spontaneous neurotransmitter secretion|activation of stimulus-independent neurotransmitter secretion|up-regulation of stimulus-independent neurotransmitter secretion|upregulation of stimulus-independent neurotransmitter secretion|up-regulation of spontaneous neurotransmitter secretion|up regulation of spontaneous neurotransmitter secretion				An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).		pad	2015-03-17T10:37:23Z						biological_process											owl:Class	
GO:0003004	biolink:NamedThing	follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage	The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis.	got7fsn_ti	follicular fluid formation in ovarian follicle antrum during distinct antral spaces stage													biological_process											owl:Class	
GO:0015465	biolink:NamedThing	obsolete lysin activity	OBSOLETE. An agent that can lyse cells.	got7fsn_ti	lysin activity				This term was made obsolete because it represents a class of gene products.	GO:0019835				True				molecular_function											owl:Class	
GO:0050751	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006268	biolink:NamedThing	DNA unwinding involved in DNA replication	The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.	got7fsn_ti	DNA unwinding factor|DNA unwinding during replication				Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.									biological_process											owl:Class	
GO:0099169	biolink:NamedThing	anchored component of postsynaptic specialization membrane of symmetric synapse	The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti							dos	2017-09-10T12:01:53Z						cellular_component											owl:Class	
GO:0003250	biolink:NamedThing	regulation of cell proliferation involved in heart valve morphogenesis	Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.	got7fsn_ti							dph	2009-10-13T02:03:42Z						biological_process											owl:Class	
GO:0072752	biolink:NamedThing	cellular response to rapamycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.	got7fsn_ti							mah	2012-09-14T11:13:34Z						biological_process											owl:Class	
GO:0019017	biolink:NamedThing	obsolete segmented viral genome	OBSOLETE. A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:0036287	biolink:NamedThing	response to iloperidone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-16T05:01:29Z						biological_process											owl:Class	
GO:1903162	biolink:NamedThing	obsolete serine transmembrane transporter activity involved in serine import into cell	OBSOLETE. Any serine transmembrane transporter activity that is involved in serine import into cell.	got7fsn_ti	serine transmembrane transporter activity involved in serine import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:44Z		True				molecular_function											owl:Class	
GO:0014052	biolink:NamedThing	regulation of gamma-aminobutyric acid secretion	Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.	got7fsn_ti	regulation of GABA secretion													biological_process											owl:Class	
GO:1902551	biolink:NamedThing	regulation of catalase activity	Any process that modulates the frequency, rate or extent of catalase activity.	got7fsn_ti	regulation of heme catalase activity|regulation of CAT|regulation of catalase reaction|regulation of bacterial catalase-peroxidase activity|regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|regulation of catalase-peroxidase activity|regulation of caperase activity|regulation of haem catalase activity|regulation of manganese catalase activity|regulation of equilase activity|regulation of optidase activity						tb	2013-12-04T21:55:46Z						biological_process											owl:Class	
GO:0140485	biolink:NamedThing	5-aminolevulinic acid transmembrane transporter activity	Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19527					pg	2020-06-29T09:02:26Z				RHEA:64816		molecular_function											owl:Class	
GO:0070723	biolink:NamedThing	response to cholesterol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.	got7fsn_ti							mah	2009-06-15T02:28:27Z						biological_process											owl:Class	
GO:0009820	biolink:NamedThing	alkaloid metabolic process	The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).	got7fsn_ti	alkaloid metabolism													biological_process											owl:Class	
GO:0032340	biolink:NamedThing	positive regulation of inhibin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell.	got7fsn_ti	stimulation of inhibin secretion|up-regulation of inhibin secretion|activation of inhibin secretion|upregulation of inhibin secretion|up regulation of inhibin secretion													biological_process											owl:Class	
GO:0052583	biolink:NamedThing	obsolete oxidoreductase activity, acting on halogen in donors	OBSOLETE. Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20613			This term was obsoleted because EC obsoleted it, and there was no other evidence that this function exists.			2010-08-13T10:14:12Z		True		EC:1.22.-.-		molecular_function											owl:Class	
OBO:OBA_0000101	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031446	biolink:NamedThing	regulation of fast-twitch skeletal muscle fiber contraction	Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.	got7fsn_ti	regulation of fast-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:0033478	biolink:NamedThing	UDP-rhamnose metabolic process	The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-rhamnose metabolism											MetaCyc:PWY-3261		biological_process											owl:Class	
GO:2000694	biolink:NamedThing	regulation of phragmoplast microtubule organization	Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization.	got7fsn_ti	regulation of phragmoplast microtubule cytoskeleton organization|regulation of phragmoplast microtubule organisation						tb	2011-05-13T09:32:27Z						biological_process											owl:Class	
GO:1902001	biolink:NamedThing	fatty acid transmembrane transport	The process in which a fatty acid is transported across a membrane.	got7fsn_ti							pr	2013-03-21T09:57:00Z						biological_process											owl:Class	
GO:0009354	biolink:NamedThing	obsolete dihydrolipoamide S-succinyltransferase complex	OBSOLETE. An enzyme complex that catalyzes the transfer of succinyl-CoA to dihydrolipoamide to form S-succinyldihydrolipoamide. The enzyme is a component of the multienzyme 2-oxoglutarate dehydrogenase complex.	got7fsn_ti	dihydrolipoamide S-succinyltransferase complex				This term was made obsolete because dihydrolipoamide S-succinyltransferase itself is not a complex, it is a component of the 2-oxoglutarate dehydrogenase complex, the activity dihydrolipoamide S-succinyltransferase is contained in a single polypeptide.	GO:0045252				True				cellular_component											owl:Class	
GO:0043524	biolink:NamedThing	negative regulation of neuron apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.	got7fsn_ti	neuron survival|negative regulation of programmed cell death, neurons|down-regulation of neuron apoptosis|down regulation of neuron apoptosis|downregulation of neuron apoptosis|inhibition of neuron apoptosis|negative regulation of neuron apoptosis													biological_process											owl:Class	
GO:1900187	biolink:NamedThing	regulation of cell adhesion involved in single-species biofilm formation	Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.	got7fsn_ti	regulation of cell adhesion during single-species biofilm formation						di	2012-03-19T12:38:45Z						biological_process											owl:Class	
GO:1902980	biolink:NamedThing	synthesis of RNA primer involved in premeiotic DNA replication	Any synthesis of RNA primer involved in meiotic cell cycle DNA replication.	got7fsn_ti	synthesis of RNA primer involved in meiotic cell cycle DNA replication						jl	2014-05-06T19:19:54Z						biological_process											owl:Class	
GO:1901178	biolink:NamedThing	spheroidene metabolic process	The chemical reactions and pathways involving spheroidene.	got7fsn_ti	spheroidene metabolism						yaf	2012-07-19T09:48:54Z						biological_process											owl:Class	
GO:1904708	biolink:NamedThing	regulation of granulosa cell apoptotic process	Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.	got7fsn_ti	regulation of granulosa cell apoptosis|regulation of granulosa cell of ovary apoptosis|regulation of granulosa cell of ovary apoptotic process						sl	2015-10-01T16:09:38Z						biological_process											owl:Class	
GO:0042927	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033388	biolink:NamedThing	putrescine biosynthetic process from arginine	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.	got7fsn_ti	putrescine synthesis from arginine|putrescine anabolism from arginine|putrescine formation from arginine|putrescine biosynthesis from arginine													biological_process											owl:Class	
CHEBI:17750	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902542	biolink:NamedThing	regulation of protein localization to mitotic spindle pole body	Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.	got7fsn_ti	regulation of protein localisation to mitotic spindle pole body						al	2013-12-04T13:47:09Z						biological_process											owl:Class	
GO:0098541	biolink:NamedThing	cytoplasmic side of trans-Golgi network transport vesicle membrane	The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm.	got7fsn_ti	external side of trans-Golgi network transport vesicle membrane						dos	2013-10-24T11:56:30Z						cellular_component											owl:Class	
GO:0051574	biolink:NamedThing	positive regulation of histone H3-K9 methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.	got7fsn_ti	upregulation of histone H3-K9 methylation|up-regulation of histone H3-K9 methylation|stimulation of histone H3-K9 methylation|activation of histone H3-K9 methylation|up regulation of histone H3-K9 methylation													biological_process											owl:Class	
GO:1904309	biolink:NamedThing	response to cordycepin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.	got7fsn_ti	response to 3'-deoxyadenosine						sl	2015-06-10T17:10:29Z						biological_process											owl:Class	
GO:0045869	biolink:NamedThing	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.	got7fsn_ti	negative regulation of retroviral genome replication|down-regulation of retroviral genome replication|inhibition of retroviral genome replication|down regulation of retroviral genome replication|downregulation of retroviral genome replication|regulation of retroviral genome replication													biological_process											owl:Class	
GO:1901944	biolink:NamedThing	miltiradiene metabolic process	The chemical reactions and pathways involving miltiradiene.	got7fsn_ti	miltiradiene metabolism						ms	2013-02-18T15:50:23Z						biological_process											owl:Class	
GO:2000489	biolink:NamedThing	regulation of hepatic stellate cell activation	Any process that modulates the frequency, rate or extent of hepatic stellate cell activation.	got7fsn_ti							bf	2011-03-14T03:48:32Z						biological_process											owl:Class	
GO:1903510	biolink:NamedThing	mucopolysaccharide metabolic process	The chemical reactions and pathways involving mucopolysaccharide.	got7fsn_ti	mucopolysaccharide metabolism						dph	2014-10-01T21:55:47Z						biological_process											owl:Class	
GO:0039542	biolink:NamedThing	obsolete suppression by virus of host RIG-I K63-linked ubiquitination	OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of K63-linked ubiquitination of RIG-I (also known as DDX58), thereby suppressing RIG-I signal transduction. Lys63-linked ubiquitination of the N-terminal CARD domains of RIG-I is crucial for the cytosolic RIG-I signaling pathway to elicit host antiviral innate immunity.	got7fsn_ti	inhibition by virus of TRIM25-mediated ubiquitination of host RIG-I|inhibition by virus of host DDX58 K63-linked ubiquitination|inhibition by virus of host RIG-I activity by inhibition of RIG-I ubiquitination				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-18T02:30:29Z		True				biological_process											owl:Class	
GO:0043835	biolink:NamedThing	obsolete uracil/thymine dehydrogenase activity	OBSOLETE. Catalysis of the reactions: uracil + H2O + acceptor = barbiturate + reduced acceptor; and thymine + H2O + acceptor = 5-methylbarbiturate + reduced acceptor.	got7fsn_ti	uracil/thymine dehydrogenase activity|uracil oxidase activity|uracil-thymine oxidase activity|uracil:acceptor oxidoreductase activity				This term was made obsolete because it represents two separate molecular functions.	GO:0052620|GO:0050383				True		EC:1.17.99.4		molecular_function											owl:Class	
GO:1904995	biolink:NamedThing	negative regulation of leukocyte adhesion to vascular endothelial cell	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.	got7fsn_ti	down-regulation of leukocyte adhesion to vascular endothelial cell|inhibition of leukocyte adhesion to vascular endothelial cell|downregulation of leukocyte adhesion to vascular endothelial cell|down regulation of leukocyte adhesion to vascular endothelial cell						bc	2016-03-01T10:59:08Z						biological_process											owl:Class	
GO:0044048	biolink:NamedThing	obsolete interaction with host via protein secreted by type V secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type V secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
CHEBI:17716	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001655	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032963	biolink:NamedThing	collagen metabolic process	The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).	got7fsn_ti	collagen metabolism													biological_process											owl:Class	
GO:1903350	biolink:NamedThing	response to dopamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.	got7fsn_ti							mr	2014-08-19T19:33:26Z						biological_process											owl:Class	
GO:0043610	biolink:NamedThing	regulation of carbohydrate utilization	Any process that modulates the frequency, rate or extent of carbohydrate utilization.	got7fsn_ti	regulation of sugar utilization													biological_process											owl:Class	
GO:1902583	biolink:NamedThing	obsolete multi-organism intracellular transport	OBSOLETE. An intracellular transport which involves another organism.	got7fsn_ti	multi organism intracellular transport				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-18T14:04:58Z		True				biological_process											owl:Class	
GO:0010860	biolink:NamedThing	obsolete proteasome regulator activity	OBSOLETE. Modulates the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.	got7fsn_ti	proteasome regulator activity				The term was made obsolete because 'proteasome' is not a valid molecular function term.	GO:0061136|GO:0061135				True				molecular_function											owl:Class	
GO:1990835	biolink:NamedThing	obsolete insulin-like growth factor production	OBSOLETE. The appearance of an insulin-like growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti	IGF production				This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-08-24T16:30:53Z		True				biological_process											owl:Class	
GO:0001526	biolink:NamedThing	obsolete proteoglycan sulfate transfer	OBSOLETE. Transfer of sulfate to a proteoglycan (a glycoprotein whose carbohydrate units are glycosaminoglycans) using 3'-phosphoadenyl sulfate.	got7fsn_ti	proteoglycan sulphate transfer|proteoglycan sulfate transfer				This term was made obsolete because it represents a group of molecular functions.	GO:0050698|GO:0006790|GO:0006029				True				biological_process											owl:Class	
GO:1903586	biolink:NamedThing	positive regulation of histone deubiquitination	Any process that activates or increases the frequency, rate or extent of histone deubiquitination.	got7fsn_ti	activation of histone deubiquitylation|upregulation of histone deubiquitylation|upregulation of histone deubiquitinylation|up-regulation of histone deubiquitinylation|upregulation of histone deubiquitination|activation of histone deubiquitination|positive regulation of histone deubiquitinylation|activation of histone deubiquitinylation|up regulation of histone deubiquitination|up-regulation of histone deubiquitination|positive regulation of histone deubiquitylation|up-regulation of histone deubiquitylation|up regulation of histone deubiquitinylation|up regulation of histone deubiquitylation						lb	2014-11-03T13:47:44Z						biological_process											owl:Class	
GO:0046769	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000385	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0110137	biolink:NamedThing	regulation of imaginal disc-derived leg joint morphogenesis	Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.	got7fsn_ti							kmv	2019-02-12T15:31:25Z						biological_process											owl:Class	
GO:0090232	biolink:NamedThing	positive regulation of spindle checkpoint	Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.	got7fsn_ti	spindle checkpoint activation						tb	2010-01-20T10:29:43Z						biological_process											owl:Class	
GO:0070344	biolink:NamedThing	regulation of fat cell proliferation	Any process that modulates the frequency, rate or extent of fat cell proliferation.	got7fsn_ti	regulation of adipose cell proliferation|regulation of adipocyte proliferation													biological_process											owl:Class	
GO:0030823	biolink:NamedThing	obsolete regulation of cGMP metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP.	got7fsn_ti	regulation of cGMP metabolism				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:1900934	biolink:NamedThing	positive regulation of nonadec-1-ene metabolic process	Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process.	got7fsn_ti	up regulation of nonadec-1-ene metabolic process|up-regulation of nonadec-1-ene metabolism|up regulation of nonadec-1-ene metabolism|up-regulation of nonadec-1-ene metabolic process|upregulation of nonadec-1-ene metabolic process|positive regulation of nonadec-1-ene metabolism|activation of nonadec-1-ene metabolism|activation of nonadec-1-ene metabolic process|upregulation of nonadec-1-ene metabolism						tt	2012-06-14T03:11:58Z						biological_process											owl:Class	
GO:0009162	biolink:NamedThing	deoxyribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	deoxyribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0003791	biolink:NamedThing	obsolete membrane associated actin binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	membrane associated actin binding				This term was made obsolete because it contains both component and function information.	GO:0016020|GO:0003779				True				molecular_function											owl:Class	
GO:0032110	biolink:NamedThing	regulation of protein histidine kinase activity	Any process that modulates the frequency, rate or extent of protein histidine kinase activity.	got7fsn_ti														biological_process											owl:Class	
GO:0035731	biolink:NamedThing	dinitrosyl-iron complex binding	Binding to a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO.	got7fsn_ti	dinitrosyl-diglutathionyl-iron complex binding|DNDGIC binding|DNIC binding						bf	2011-03-11T09:58:31Z						molecular_function											owl:Class	
GO:0045564	biolink:NamedThing	obsolete positive regulation of TRAIL receptor biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.	got7fsn_ti	up regulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor biosynthesis|positive regulation of TRAIL receptor anabolism|stimulation of TRAIL receptor biosynthetic process|upregulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor synthesis|up-regulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor formation|activation of TRAIL receptor biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:0032817	biolink:NamedThing	regulation of natural killer cell proliferation	Any process that modulates the frequency, rate or extent of natural killer cell proliferation.	got7fsn_ti	regulation of NK cell proliferation													biological_process											owl:Class	
GO:1903906	biolink:NamedThing	regulation of plasma membrane raft polarization	Any process that modulates the frequency, rate or extent of plasma membrane raft polarization.	got7fsn_ti							als	2015-02-09T10:53:56Z						biological_process											owl:Class	
GO:1904181	biolink:NamedThing	positive regulation of membrane depolarization	Any process that activates or increases the frequency, rate or extent of membrane depolarization.	got7fsn_ti	upregulation of membrane depolarization|up regulation of membrane depolarization|activation of membrane depolarization|up-regulation of membrane depolarization						sl	2015-04-29T22:29:31Z						biological_process											owl:Class	
CL:0000722	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046211	biolink:NamedThing	(+)-camphor biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone.	got7fsn_ti	(+)-camphor anabolism|(+)-camphor biosynthesis|(+)-camphor synthesis|(+)-camphor formation													biological_process											owl:Class	
GO:1904473	biolink:NamedThing	response to L-dopa	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.	got7fsn_ti							sl	2015-07-09T20:15:53Z						biological_process											owl:Class	
GO:0061999	biolink:NamedThing	regulation of cardiac endothelial to mesenchymal transition	Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition.	got7fsn_ti							dph	2018-02-16T16:26:51Z						biological_process											owl:Class	
GO:0051618	biolink:NamedThing	positive regulation of histamine uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.	got7fsn_ti	upregulation of histamine uptake|stimulation of histamine uptake|positive regulation of histamine import|up regulation of histamine uptake|activation of histamine uptake|up-regulation of histamine uptake													biological_process											owl:Class	
GO:1990702	biolink:NamedThing	integral component of Golgi cis cisterna membrane	The component of the Golgi cis membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral component of cis-Golgi cisterna membrane						bhm	2015-03-16T16:03:21Z						cellular_component											owl:Class	
GO:2000258	biolink:NamedThing	negative regulation of protein activation cascade	Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade.	got7fsn_ti	negative regulation of protein activitory cascade|negative regulation of protein activation pathway						mah	2010-11-23T11:33:51Z						biological_process											owl:Class	
GO:0008717	biolink:NamedThing	obsolete D-alanyl-D-alanine endopeptidase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	penicillin-binding protein 8|D-alanyl-D-alanine endopeptidase activity|penicillin-binding protein 7			GO:0004175	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:3015	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034165	biolink:NamedThing	positive regulation of toll-like receptor 9 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.	got7fsn_ti	positive regulation of TLR9 signaling pathway|positive regulation of toll-like receptor 9 signalling pathway													biological_process											owl:Class	
GO:2000049	biolink:NamedThing	positive regulation of cell-cell adhesion mediated by cadherin	Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin.	got7fsn_ti							jl	2010-08-20T12:56:57Z						biological_process											owl:Class	
GO:1902928	biolink:NamedThing	inulin biosynthetic process	The chemical reactions and pathways resulting in the formation of inulin.	got7fsn_ti	inulin anabolism|inulin formation|inulin biosynthesis|inulin synthesis				SUC2 in S. cerevisiae strain JZ1C in PMID:23104410.		se	2014-04-21T23:54:51Z						biological_process											owl:Class	
GO:0008578	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904568	biolink:NamedThing	cellular response to wortmannin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.	got7fsn_ti	cellular response to wartmannin						sl	2015-08-19T16:22:34Z						biological_process											owl:Class	
GO:0010825	biolink:NamedThing	positive regulation of centrosome duplication	Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	got7fsn_ti														biological_process											owl:Class	
GO:0070230	biolink:NamedThing	positive regulation of lymphocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.	got7fsn_ti	up regulation of lymphocyte apoptosis|stimulation of lymphocyte apoptosis|positive regulation of lymphocyte apoptosis|up-regulation of lymphocyte apoptosis|upregulation of lymphocyte apoptosis|activation of lymphocyte apoptosis				Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).									biological_process											owl:Class	
GO:0042738	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010899	biolink:NamedThing	regulation of phosphatidylcholine catabolic process	Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	got7fsn_ti														biological_process											owl:Class	
GO:0042624	biolink:NamedThing	obsolete ATPase activity, uncoupled	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction is not directly coupled to any other reaction.	got7fsn_ti					The reason for obsoletion is that the there is no convincing example of a protein with this function.					True				molecular_function											owl:Class	
CHEBI:16096	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043930	biolink:NamedThing	primary ovarian follicle growth involved in primary follicle stage	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis.	got7fsn_ti	primary ovarian follicle growth during primary follicle stage													biological_process											owl:Class	
GO:1900354	biolink:NamedThing	regulation of methanofuran metabolic process	Any process that modulates the frequency, rate or extent of methanofuran metabolic process.	got7fsn_ti	regulation of methanofuran metabolism						tt	2012-04-06T02:15:44Z						biological_process											owl:Class	
GO:0101018	biolink:NamedThing	negative regulation of mitotic DNA replication initiation from late origin	Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.	got7fsn_ti	negative regulation of late replication origin firing						mec							biological_process											owl:Class	
GO:0072718	biolink:NamedThing	response to cisplatin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.	got7fsn_ti							mah	2012-04-30T11:31:05Z						biological_process											owl:Class	
GO:0019497	biolink:NamedThing	hexachlorocyclohexane metabolic process	The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution.	got7fsn_ti	hexachlorocyclohexane metabolism													biological_process											owl:Class	
GO:1900530	biolink:NamedThing	obsolete regulation of cell shape involved in cellular response to salt stress	OBSOLETE. Any regulation of cell shape that is involved in cellular response to salt stress.	got7fsn_ti	regulation of cell shape of cellular response to salt stress|regulation of cell shape of cellular salinity response|regulation of cell shape of cellular response to ionic osmotic stress|regulation of cell shape involved in cellular response to salt stress				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2012-05-08T01:48:01Z		True				biological_process											owl:Class	
UBERON:0006694	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0039570	biolink:NamedThing	obsolete suppression by virus of host STAT2 activity by negative regulation of STAT protein import into nucleus	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by retaining STAT2 in the cytoplasm, so STAT2 is unable to translocate to the nucleus to activate transcription of its target genes.	got7fsn_ti	cytoplasmic sequestration of STAT2|cytoplasmic sequestering of STAT2				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:46:49Z		True				biological_process											owl:Class	
GO:0070808	biolink:NamedThing	regulation of Hulle cell development	Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.	got7fsn_ti							mah	2009-07-08T04:51:33Z						biological_process											owl:Class	
UBERON:0001001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150005	biolink:NamedThing	enzyme activator complex	A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active.	got7fsn_ti														cellular_component											owl:Class	
GO:0060991	biolink:NamedThing	obsolete lipid tube assembly involved in cytokinesis	OBSOLETE. The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in cytokinesis.	got7fsn_ti	lipid tubulation involved in cytokinesis|lipid tube assembly involved in cytokinesis				This term was made obsolete because there is no evidence the process exists.		dph	2010-01-11T02:22:25Z		True				biological_process											owl:Class	
CL:0000726	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0080091	biolink:NamedThing	regulation of raffinose metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose.	got7fsn_ti							dhl	2009-04-22T04:36:27Z						biological_process											owl:Class	
CHEBI:76931	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030087	biolink:NamedThing	obsolete PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex			GO:0009655	This term was made obsolete because the 'complex' it refers to contains only one gene product.					True				cellular_component											owl:Class	
GO:0043692	biolink:NamedThing	monoterpene metabolic process	The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure.	got7fsn_ti	monoterpene metabolism													biological_process											owl:Class	
GO:0010914	biolink:NamedThing	positive regulation of sterigmatocystin biosynthetic process	Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	got7fsn_ti														biological_process											owl:Class	
GO:2000101	biolink:NamedThing	regulation of mammary stem cell proliferation	Any process that modulates the frequency, rate or extent of mammary stem cell proliferation.	got7fsn_ti							dph	2010-09-14T06:10:32Z						biological_process											owl:Class	
GO:2000966	biolink:NamedThing	regulation of cell wall polysaccharide catabolic process	Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process.	got7fsn_ti	regulation of cell wall polysaccharide breakdown						tt	2011-08-01T02:30:27Z						biological_process											owl:Class	
GO:1903729	biolink:NamedThing	regulation of plasma membrane organization	Any process that modulates the frequency, rate or extent of plasma membrane organization.	got7fsn_ti	regulation of plasma membrane organisation|regulation of plasma membrane organization and biogenesis						al	2014-12-10T18:59:44Z						biological_process											owl:Class	
GO:0017038	biolink:NamedThing	protein import	The targeting and directed movement of proteins into a cell or organelle.  Not all import involves an initial targeting event.	got7fsn_ti	protein uptake													biological_process											owl:Class	
GO:1901202	biolink:NamedThing	negative regulation of extracellular matrix assembly	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.	got7fsn_ti	downregulation of extracellular matrix assembly|down regulation of extracellular matrix assembly|inhibition of extracellular matrix assembly|down-regulation of extracellular matrix assembly						rl	2012-07-27T04:04:24Z						biological_process											owl:Class	
GO:1904794	biolink:NamedThing	negative regulation of euchromatin binding	Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding.	got7fsn_ti	down-regulation of euchromatin binding|inhibition of euchromatin binding|downregulation of euchromatin binding|down regulation of euchromatin binding						nc	2015-11-09T11:43:12Z						biological_process											owl:Class	
CHEBI:16244	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025280	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50860	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090065	biolink:NamedThing	regulation of production of siRNA involved in RNA interference	Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.	got7fsn_ti	regulation of RNA interference, production of siRNA						tb	2009-08-12T11:41:09Z						biological_process											owl:Class	
GO:0000167	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001104	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:35172	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007970	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015982	biolink:NamedThing	obsolete antiport	OBSOLETE. The process of coupled solute translocation in which two solutes equilibrate across an osmotic barrier, the translocation of solute being coupled to the translocation of the other in the opposite direction.	got7fsn_ti	antiport			GO:0015297	This term was made obsolete because it represents a molecular function rather than a biological process.					True				biological_process											owl:Class	
GO:0075312	biolink:NamedThing	negative regulation of sporangium development	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.	got7fsn_ti														biological_process											owl:Class	
CL:0005012	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019240	biolink:NamedThing	citrulline biosynthetic process	The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.	got7fsn_ti	citrulline synthesis|citrulline formation|citrulline biosynthesis|citrulline anabolism											MetaCyc:CITRULBIO-PWY		biological_process											owl:Class	
GO:0052514	biolink:NamedThing	obsolete positive regulation by organism of symbiont inflammatory response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of symbiont inflammatory response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0100048	biolink:NamedThing	obsolete positive regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylcholine biosynthetic process.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0010728	biolink:NamedThing	regulation of hydrogen peroxide biosynthetic process	Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	got7fsn_ti	regulation of hydrogen peroxide biosynthesis													biological_process											owl:Class	
GO:0099087	biolink:NamedThing	anterograde axonal transport of messenger ribonucleoprotein complex	The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse.	got7fsn_ti	anterograde axonal transport of mRNA RNP complex													biological_process											owl:Class	
GO:0014053	biolink:NamedThing	negative regulation of gamma-aminobutyric acid secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.	got7fsn_ti	downregulation of gamma-aminobutyric acid secretion|negative regulation of GABA secretion|down-regulation of gamma-aminobutyric acid secretion|inhibition of gamma-aminobutyric acid secretion|down regulation of gamma-aminobutyric acid secretion													biological_process											owl:Class	
GO:0006212	biolink:NamedThing	uracil catabolic process	The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.	got7fsn_ti	uracil catabolism|uracil degradation|uracil breakdown													biological_process											owl:Class	
CHEBI:27385	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075124	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015691	biolink:NamedThing	cadmium ion transport	The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	cadmium transport													biological_process											owl:Class	
GO:2001006	biolink:NamedThing	regulation of cellulose biosynthetic process	Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.	got7fsn_ti	regulation of cellulose formation|regulation of cellulose anabolism|regulation of cellulose synthesis|regulation of cellulose biosynthesis						tt	2011-08-08T08:42:17Z						biological_process											owl:Class	
GO:0099063	biolink:NamedThing	integral component of postsynaptic recycling endosome membrane	The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0000180	biolink:NamedThing	obsolete cytosolic large ribosomal subunit	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytosolic large ribosomal subunit				This term was made obsolete because more specific children exist.	GO:0022625				True				cellular_component											owl:Class	
GO:0044698	biolink:NamedThing	obsolete morphogenesis of symbiont in host cell	OBSOLETE. The process in which a symbiont undergoes a change in shape or form, within the host's cell.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20305			This term was obsoleted because it represents both a process and a location.		jl	2012-09-19T14:10:53Z		True				biological_process											owl:Class	
GO:0052014	biolink:NamedThing	obsolete catabolism by symbiont of host protein	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of host protein	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
GO:0036096	biolink:NamedThing	obsolete 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing	OBSOLETE. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming the mature 3' end of a miRNA from a pre-miRNA.	got7fsn_ti	3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing|exonucleolytic trimming to generate 3' end of miRNA from pre-miRNA				This term was made obsolete because it is not real a process, and was created accidentally.		bf	2012-01-24T02:29:03Z		True				molecular_function											owl:Class	
GO:0110144	biolink:NamedThing	obsolete magnetosome part	OBSOLETE. Any constituent part of a magnetosome, a membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria.	got7fsn_ti						GO:0110143	kmv	2019-05-30T17:36:02Z		True				cellular_component											owl:Class	
GO:0034887	biolink:NamedThing	obsolete 1,4-dihydroisonicotinate 2,3-dioxygenase activity	OBSOLETE. Catalysis of the reaction: 1,4-dihydroisonicotinate + O2 = gamma-N-formylaminovinylacetaldehyde + CO2.	got7fsn_ti	1,4-dihydroisonicotinate 2,3-dioxygenase activity				This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.	GO:0016702				True				molecular_function											owl:Class	
SO:0000167	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900079	biolink:NamedThing	regulation of arginine biosynthetic process	Any process that modulates the frequency, rate or extent of arginine biosynthetic process.	got7fsn_ti	regulation of arginine biosynthesis|regulation of arginine synthesis|regulation of arginine formation|regulation of arginine anabolism						pr	2012-02-01T03:57:36Z						biological_process											owl:Class	
GO:0061183	biolink:NamedThing	regulation of dermatome development	Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.	got7fsn_ti							dph	2010-07-14T08:40:26Z						biological_process											owl:Class	
GO:0046038	biolink:NamedThing	GMP catabolic process	The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.	got7fsn_ti	GMP degradation|GMP breakdown|GMP catabolism													biological_process											owl:Class	
GO:0009786	biolink:NamedThing	regulation of asymmetric cell division	Any process that modulates the frequency, rate or extent of asymmetric cell division.	got7fsn_ti														biological_process											owl:Class	
GO:0034155	biolink:NamedThing	regulation of toll-like receptor 7 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.	got7fsn_ti	regulation of toll-like receptor 7 signalling pathway|regulation of TLR7 signaling pathway													biological_process											owl:Class	
GO:0033493	biolink:NamedThing	esculetin biosynthetic process	The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin.	got7fsn_ti	esculetin synthesis|esculetin formation|esculetin anabolism|esculetin biosynthesis											MetaCyc:PWY-5349		biological_process											owl:Class	
GO:1901845	biolink:NamedThing	negative regulation of cell communication by electrical coupling involved in cardiac conduction	Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.	got7fsn_ti	inhibition of cell communication by electrical coupling involved in cardiac conduction|down-regulation of cell communication by electrical coupling involved in cardiac conduction|downregulation of cell communication by electrical coupling involved in cardiac conduction|down regulation of cell communication by electrical coupling involved in cardiac conduction						rl	2013-01-24T19:15:44Z						biological_process											owl:Class	
GO:0031362	biolink:NamedThing	anchored component of external side of plasma membrane	The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti	anchored to external leaflet of plasma membrane|anchored to external side of plasma membrane													cellular_component											owl:Class	
GO:1905005	biolink:NamedThing	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.	got7fsn_ti							rl	2016-03-01T15:38:39Z						biological_process											owl:Class	
GO:0070957	biolink:NamedThing	negative regulation of neutrophil mediated killing of gram-negative bacterium	Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.	got7fsn_ti	down regulation of neutrophil mediated killing of gram-negative bacterium|down-regulation of neutrophil mediated killing of gram-negative bacterium|inhibition of neutrophil mediated killing of gram-negative bacterium|downregulation of neutrophil mediated killing of gram-negative bacterium						mah	2009-10-01T02:20:17Z						biological_process											owl:Class	
GO:0032676	biolink:NamedThing	regulation of interleukin-7 production	Any process that modulates the frequency, rate, or extent of interleukin-7 production.	got7fsn_ti	regulation of IL-7 production|regulation of interleukin-7 biosynthetic process|regulation of interleukin-7 secretion										GO:0045411|GO:0150112			biological_process											owl:Class	
CHEBI:22629	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033324	biolink:NamedThing	choline biosynthetic process via N-monomethylethanolamine	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine.	got7fsn_ti	choline anabolism via N-monomethylethanolamine|choline synthesis via N-monomethylethanolamine|choline formation via N-monomethylethanolamine|choline biosynthesis via N-monomethylethanolamine											MetaCyc:PWY-3542|MetaCyc:PWY-4762		biological_process											owl:Class	
GO:1904092	biolink:NamedThing	regulation of autophagic cell death	Any process that modulates the frequency, rate or extent of autophagic cell death.	got7fsn_ti	regulation of autophagic death|regulation of programmed cell death by autophagy|regulation of type II programmed cell death|regulation of programmed cell death by macroautophagy						bhm	2015-03-26T16:41:32Z						biological_process											owl:Class	
GO:0046864	biolink:NamedThing	isoprenoid transport	The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	got7fsn_ti														biological_process											owl:Class	
GO:0061078	biolink:NamedThing	positive regulation of prostaglandin secretion involved in immune response	Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.	got7fsn_ti	positive regulation of prostaglandin secretion during immune response						dph	2010-04-08T01:53:45Z						biological_process											owl:Class	
GO:0031110	biolink:NamedThing	regulation of microtubule polymerization or depolymerization	Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.	got7fsn_ti														biological_process											owl:Class	
GO:0009127	biolink:NamedThing	purine nucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine nucleoside monophosphate biosynthesis|purine nucleoside monophosphate synthesis|purine nucleoside monophosphate anabolism|purine nucleoside monophosphate formation													biological_process											owl:Class	
GO:2000425	biolink:NamedThing	regulation of apoptotic cell clearance	Any process that modulates the frequency, rate or extent of apoptotic cell clearance.	got7fsn_ti	regulation of programmed cell clearance|regulation of apoptotic cell removal|regulation of efferocytosis						bf	2011-02-25T11:50:11Z						biological_process											owl:Class	
GO:1905584	biolink:NamedThing	outer hair cell apoptotic process	Any apoptotic process in an outer hair cell.	got7fsn_ti	outer hair cell apoptosis|cochlear outer hair cell apoptotic process|cochlear outer hair cell apoptosis						sl	2016-10-21T22:42:13Z						biological_process											owl:Class	
GO:0016343	biolink:NamedThing	obsolete cytoskeletal anchoring activity	OBSOLETE. The direct or indirect linkage of cytoskeletal filaments to the plasma membrane.	got7fsn_ti	cytoskeletal anchoring activity				This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:1903150	biolink:NamedThing	obsolete calcium ion transmembrane transporter activity involved in calcium ion import into cell	OBSOLETE. Any calcium ion transmembrane transporter activity that is involved in calcium ion import into cell.	got7fsn_ti	calcium ion transmembrane transporter activity involved in calcium ion uptake into cell|calcium ion transmembrane transporter activity involved in calcium ion import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:36Z		True				molecular_function											owl:Class	
GO:0019625	biolink:NamedThing	atrazine catabolic process to cyanuric acid	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid.	got7fsn_ti	atrazine degradation to cyanuric acid|atrazine breakdown to cyanuric acid											MetaCyc:P141-PWY		biological_process											owl:Class	
GO:0043609	biolink:NamedThing	regulation of carbon utilization	Any process that modulates the frequency, rate, or extent of carbon utilization.	got7fsn_ti														biological_process											owl:Class	
GO:0140051	biolink:NamedThing	positive regulation of endocardial cushion to mesenchymal transition	Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition.	got7fsn_ti							pg	2017-06-26T09:11:03Z						biological_process											owl:Class	
GO:0033356	biolink:NamedThing	UDP-L-arabinose metabolic process	The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-L-arabinose metabolism													biological_process											owl:Class	
GO:2000453	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.	got7fsn_ti							bf	2011-03-04T10:45:20Z						biological_process											owl:Class	
GO:0008090	biolink:NamedThing	retrograde axonal transport	The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.	got7fsn_ti	retrograde axon cargo transport													biological_process											owl:Class	
GO:0060547	biolink:NamedThing	negative regulation of necrotic cell death	Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.	got7fsn_ti							dph	2009-04-13T01:51:25Z						biological_process											owl:Class	
GO:0085004	biolink:NamedThing	obsolete interaction with host via secreted substance released from haustorium	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the haustorium, a projection from a cell or tissue that penetrates the host's cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T02:58:39Z		True				biological_process											owl:Class	
GO:0072199	biolink:NamedThing	regulation of mesenchymal cell proliferation involved in ureter development	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	got7fsn_ti	regulation of ureteral mesenchymal cell proliferation|regulation of ureter mesenchymal cell proliferation						mah	2010-03-01T03:38:13Z						biological_process											owl:Class	
GO:1904389	biolink:NamedThing	rod bipolar cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell.	got7fsn_ti							sl	2015-06-23T19:01:11Z						biological_process											owl:Class	
GO:1901136	biolink:NamedThing	carbohydrate derivative catabolic process	The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative.	got7fsn_ti	carbohydrate derivative degradation|carbohydrate derivative breakdown|carbohydrate derivative catabolism						bf	2012-07-12T04:05:31Z						biological_process											owl:Class	
GO:1902630	biolink:NamedThing	regulation of membrane hyperpolarization	Any process that modulates the frequency, rate or extent of membrane hyperpolarization.	got7fsn_ti							krc	2014-01-17T18:27:56Z						biological_process											owl:Class	
GO:1900959	biolink:NamedThing	regulation of 17-methylnonadec-1-ene metabolic process	Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.	got7fsn_ti	regulation of 17-methylnonadec-1-ene metabolism						tt	2012-06-14T03:29:27Z						biological_process											owl:Class	
GO:0060159	biolink:NamedThing	regulation of dopamine receptor signaling pathway	Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.	got7fsn_ti	regulation of dopamine receptor signalling pathway													biological_process											owl:Class	
GO:0075148	biolink:NamedThing	obsolete positive regulation of signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0099076	biolink:NamedThing	mitochondrion to peroxisome transport	Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles.	got7fsn_ti														biological_process											owl:Class	
GO:0052274	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034149	biolink:NamedThing	positive regulation of toll-like receptor 5 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway.	got7fsn_ti	positive regulation of TLR5 signaling pathway|positive regulation of toll-like receptor 5 signalling pathway													biological_process											owl:Class	
GO:0032932	biolink:NamedThing	negative regulation of astral microtubule depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules.	got7fsn_ti	astral microtubule stabilization													biological_process											owl:Class	
GO:0046248	biolink:NamedThing	alpha-pinene biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.	got7fsn_ti	alpha-pinene biosynthesis|alpha-pinene anabolism|alpha-pinene formation|alpha-pinene synthesis													biological_process											owl:Class	
GO:2000291	biolink:NamedThing	regulation of myoblast proliferation	Any process that modulates the frequency, rate or extent of myoblast proliferation.	got7fsn_ti							mah	2010-12-20T10:34:26Z						biological_process											owl:Class	
GO:0031000	biolink:NamedThing	response to caffeine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.	got7fsn_ti														biological_process											owl:Class	
GO:0072512	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905674	biolink:NamedThing	regulation of adaptive immune memory response	Any process that modulates the frequency, rate or extent of adaptive immune memory response.	got7fsn_ti							tb	2016-11-11T22:24:33Z						biological_process											owl:Class	
GO:1902088	biolink:NamedThing	plant-type cell wall loosening involved in abscission	Any plant-type cell wall loosening that is involved in abscission.	got7fsn_ti	cellulose and pectin-containing cell wall loosening involved in abscission						tb	2013-04-26T18:34:45Z						biological_process											owl:Class	
CHEBI:23456	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902782	biolink:NamedThing	response to decane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.	got7fsn_ti							tt	2014-03-21T12:50:08Z						biological_process											owl:Class	
GO:0060761	biolink:NamedThing	negative regulation of response to cytokine stimulus	Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.	got7fsn_ti							dph	2009-06-22T02:59:57Z						biological_process											owl:Class	
GO:1904633	biolink:NamedThing	regulation of glomerular visceral epithelial cell apoptotic process	Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.	got7fsn_ti	regulation of glomerular podocyte apoptosis|regulation of glomerular visceral epithelial cell apoptosis|regulation of podocyte apoptosis|regulation of glomerular podocyte apoptotic process|regulation of podocyte apoptotic process						sl	2015-08-28T14:14:44Z						biological_process											owl:Class	
GO:1902132	biolink:NamedThing	(+)-lariciresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-lariciresinol.	got7fsn_ti	(+)-lariciresinol formation|(+)-lariciresinol anabolism|(+)-lariciresinol biosynthesis|(+)-lariciresinol synthesis						ms	2013-05-21T08:49:59Z						biological_process											owl:Class	
GO:0075319	biolink:NamedThing	positive regulation of ascus development	Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.	got7fsn_ti														biological_process											owl:Class	
GO:0001577	biolink:NamedThing	obsolete galectin	OBSOLETE. A lectin that exhibits calcium independent binding of beta-galactoside sugars.	got7fsn_ti	S-type lectin|galectin				This term was made obsolete because it refers to a class of gene products.	GO:0007157|GO:0016936				True				molecular_function											owl:Class	
GO:1905034	biolink:NamedThing	regulation of antifungal innate immune response	Any process that modulates the frequency, rate or extent of an antifungal innate immune response.	got7fsn_ti							dph	2016-03-07T20:07:54Z						biological_process											owl:Class	
GO:1900132	biolink:NamedThing	positive regulation of lipid binding	Any process that activates or increases the frequency, rate or extent of lipid binding.	got7fsn_ti	up regulation of lipid binding|up-regulation of lipid binding|upregulation of lipid binding|activation of lipid binding						pm	2012-02-23T04:05:11Z						biological_process											owl:Class	
UBERON:0005331	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900825	biolink:NamedThing	regulation of membrane depolarization during cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.	got7fsn_ti							rl	2012-06-06T04:15:20Z						biological_process											owl:Class	
PO:0002000	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64702	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045671	biolink:NamedThing	negative regulation of osteoclast differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.	got7fsn_ti	down regulation of osteoclast differentiation|inhibition of osteoclast differentiation|downregulation of osteoclast differentiation|down-regulation of osteoclast differentiation													biological_process											owl:Class	
GO:1900863	biolink:NamedThing	positive regulation of cordyol C biosynthetic process	Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process.	got7fsn_ti	activation of cordyol C biosynthetic process|up-regulation of cordyol C biosynthetic process|up regulation of cordyol C biosynthetic process|upregulation of cordyol C biosynthetic process						di	2012-06-07T01:56:46Z						biological_process											owl:Class	
UBERON:0002149	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:53463	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000638	biolink:NamedThing	regulation of SREBP signaling pathway	Any process that modulates the frequency, rate or extent of the SREBP signaling pathway.	got7fsn_ti	regulation of SREBP-mediated signaling pathway|regulation of SREBP-mediated signalling pathway						vk	2011-04-20T02:45:59Z						biological_process											owl:Class	
GO:0015296	biolink:NamedThing	anion:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0005551	biolink:NamedThing	obsolete ubiquitin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti					This term was made obsolete because it represents a gene product.	GO:0031386|GO:0016567				True				molecular_function											owl:Class	
CHEBI:60819	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019762	biolink:NamedThing	glucosinolate catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.	got7fsn_ti	glucosinolate breakdown|glucosinolate degradation|glucosinolate catabolism											MetaCyc:PWY-5267		biological_process											owl:Class	
UBERON:0002167	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905686	biolink:NamedThing	positive regulation of plasma membrane repair	Any process that activates or increases the frequency, rate or extent of plasma membrane repair.	got7fsn_ti	upregulation of plasma membrane repair|up-regulation of plasma membrane repair|activation of plasma membrane repair|up regulation of plasma membrane repair						bhm	2016-11-14T10:30:46Z						biological_process											owl:Class	
GO:0071336	biolink:NamedThing	regulation of hair follicle cell proliferation	Any process that modulates the frequency, rate or extent of hair follicle cell proliferation.	got7fsn_ti							mah	2009-12-11T10:53:40Z						biological_process											owl:Class	
GO:0052225	biolink:NamedThing	obsolete energy taxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on or near a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	energy taxis on or near other organism during symbiotic interaction				This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0042408	biolink:NamedThing	obsolete myrcene/(E)-beta-ocimene synthase activity	OBSOLETE. Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes.	got7fsn_ti	myrcene/ocimene synthase activity|myrcene/(E)-beta-ocimene synthase activity				This term was made obsolete because it represents two activities.					True		EC:4.6.-.-		molecular_function											owl:Class	
GO:1903171	biolink:NamedThing	carbon dioxide homeostasis	Any process involved in the maintenance of an internal steady state of carbon dioxide within an organism or cell.	got7fsn_ti							mr	2014-07-11T20:58:24Z						biological_process											owl:Class	
GO:0009208	biolink:NamedThing	pyrimidine ribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0048641	biolink:NamedThing	regulation of skeletal muscle tissue development	Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.	got7fsn_ti														biological_process											owl:Class	
GO:0060804	biolink:NamedThing	positive regulation of Wnt signaling pathway by BMP signaling pathway	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway.	got7fsn_ti	positive regulation of WNT receptor signalling pathway by BMP signalling pathway|positive regulation of Wnt receptor signaling pathway by BMP signaling pathway|positive regulation of Wnt-activated signaling pathway by BMP signaling pathway|positive regulation of WNT receptor signaling pathway by BMP signaling pathway						dph	2009-08-06T01:52:48Z						biological_process											owl:Class	
GO:0007069	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.	got7fsn_ti	negative regulation of transcription from Pol I promoter during mitosis|downregulation of transcription from RNA polymerase I promoter during mitosis|inhibition of transcription from RNA polymerase I promoter during mitosis|mitotic repression of transcription from Pol I promoter|down regulation of transcription from RNA polymerase I promoter during mitosis|down-regulation of transcription from RNA polymerase I promoter during mitosis|negative regulation of transcription from RNA polymerase I promoter, mitotic	https://github.com/geneontology/go-ontology/issues/14896			The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0016479|GO:0044772				True				biological_process											owl:Class	
CHEBI:65331	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903874	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0014858	biolink:NamedThing	positive regulation of skeletal muscle cell proliferation	Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0070377	biolink:NamedThing	negative regulation of ERK5 cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.	got7fsn_ti	downregulation of BMK cascade|negative regulation of BMK signaling pathway|down regulation of BMK cascade|down-regulation of BMK cascade|inhibition of BMK cascade|negative regulation of BMK signalling pathway|negative regulation of BMK cascade|negative regulation of BMK1 cascade|negative regulation of MAPK7 cascade|negative regulation of ERK5 signaling pathway													biological_process											owl:Class	
CHEBI:60190	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051763	biolink:NamedThing	sesquiterpene catabolic process	The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.	got7fsn_ti														biological_process											owl:Class	
GO:0032384	biolink:NamedThing	negative regulation of intracellular cholesterol transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.	got7fsn_ti	down regulation of intracellular cholesterol transport|downregulation of intracellular cholesterol transport|inhibition of intracellular cholesterol transport|down-regulation of intracellular cholesterol transport													biological_process											owl:Class	
OBO:GOCHE_23888	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098020	biolink:NamedThing	obsolete virus tail, minor subunit	OBSOLETE. The part of the viral tail that comprises the least common subunit type.	got7fsn_ti	minor tail protein|bacteriophage minor protein subunit				The reason for obsoletion is that these are not precise structures: major (most abundant) and minor subunits of viral tails vary in different viruses/phages.		bm	2012-07-19T11:36:25Z		True				cellular_component											owl:Class	
GO:0098553	biolink:NamedThing	lumenal side of endoplasmic reticulum membrane	The side (leaflet) of the plasma membrane that faces the lumen.	got7fsn_ti							dos	2013-12-03T12:08:37Z						cellular_component											owl:Class	
GO:0015538	biolink:NamedThing	sialic acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).	got7fsn_ti	sialic acid:hydrogen symporter activity|sialic acid permease activity											Reactome:R-HSA-428585|RHEA:28987|Reactome:R-HSA-5624239		molecular_function											owl:Class	
GO:2001035	biolink:NamedThing	regulation of tongue muscle cell differentiation	Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation.	got7fsn_ti							yaf	2011-08-24T11:10:16Z						biological_process											owl:Class	
GO:1901876	biolink:NamedThing	regulation of calcium ion binding	Any process that modulates the frequency, rate or extent of calcium ion binding.	got7fsn_ti	regulation of calcium ion storage activity						rl	2013-02-06T12:38:12Z						biological_process											owl:Class	
CHEBI:65172	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060694	biolink:NamedThing	regulation of cholesterol transporter activity	Any process that modulates the rate, frequency, or extent of cholesterol transporter activity.	got7fsn_ti							dph	2009-06-08T02:05:27Z						biological_process											owl:Class	
GO:1903062	biolink:NamedThing	regulation of reverse cholesterol transport	Any process that modulates the frequency, rate or extent of reverse cholesterol transport.	got7fsn_ti							rl	2014-05-28T15:15:27Z						biological_process											owl:Class	
GO:0110080	biolink:NamedThing	positive regulation of placenta blood vessel development	Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.	got7fsn_ti							kmv	2018-02-01T14:55:30Z						biological_process											owl:Class	
CHEBI:37407	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052436	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the symbiont calcium-dependent protein kinase signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway|modulation by organism of defense-related symbiont CDPK pathway				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0010594	biolink:NamedThing	regulation of endothelial cell migration	Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.	got7fsn_ti														biological_process											owl:Class	
GO:0051590	biolink:NamedThing	positive regulation of neurotransmitter transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	activation of neurotransmitter transport|stimulation of neurotransmitter transport|up-regulation of neurotransmitter transport|up regulation of neurotransmitter transport|upregulation of neurotransmitter transport													biological_process											owl:Class	
GO:0033081	biolink:NamedThing	regulation of T cell differentiation in thymus	Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.	got7fsn_ti	regulation of thymocyte differentiation|regulation of T cell development in thymus|regulation of thymocyte cell differentiation|regulation of thymic T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:1904599	biolink:NamedThing	advanced glycation end-product binding	Binding to advanced glycation end-product.	got7fsn_ti							krc	2015-08-25T23:39:32Z						molecular_function											owl:Class	
GO:0120033	biolink:NamedThing	negative regulation of plasma membrane bounded cell projection assembly	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13298					krc	2017-04-26T04:34:31Z						biological_process											owl:Class	
GO:1901812	biolink:NamedThing	beta-carotene biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-carotene.	got7fsn_ti	beta-carotene biosynthesis|beta-carotene formation|beta-carotene synthesis|beta-carotene anabolism						yaf	2013-01-22T10:30:32Z						biological_process											owl:Class	
GO:0070248	biolink:NamedThing	negative regulation of natural killer cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process.	got7fsn_ti	negative regulation of NK cell apoptosis|negative regulation of natural killer cell apoptosis|inhibition of natural killer cell apoptosis|downregulation of natural killer cell apoptosis|down regulation of natural killer cell apoptosis|down-regulation of natural killer cell apoptosis													biological_process											owl:Class	
GO:0048324	biolink:NamedThing	regulation of axial mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination.	got7fsn_ti														biological_process											owl:Class	
GO:1901355	biolink:NamedThing	response to rapamycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.	got7fsn_ti							mah	2012-09-13T13:12:26Z						biological_process											owl:Class	
GO:2001133	biolink:NamedThing	methane biosynthetic process from methanethiol	The chemical reactions and pathways resulting in the formation of a methane from a methanethiol.	got7fsn_ti							jl	2011-10-13T12:32:57Z						biological_process											owl:Class	
CHEBI:26490	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_50249	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900193	biolink:NamedThing	regulation of oocyte maturation	Any process that modulates the frequency, rate or extent of oocyte maturation.	got7fsn_ti							kmv	2012-03-19T09:41:18Z						biological_process											owl:Class	
GO:0050858	biolink:NamedThing	negative regulation of antigen receptor-mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.	got7fsn_ti	down regulation of antigen receptor-mediated signaling pathway|inhibition of antigen receptor-mediated signaling pathway|negative regulation of antigen receptor mediated signalling pathway|downregulation of antigen receptor-mediated signaling pathway|down-regulation of antigen receptor-mediated signaling pathway													biological_process											owl:Class	
GO:0010872	biolink:NamedThing	regulation of cholesterol esterification	Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.	got7fsn_ti														biological_process											owl:Class	
UBERON:0001905	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002527	biolink:NamedThing	vasodilation involved in acute inflammatory response	An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response.	got7fsn_ti	vasodilation during acute inflammatory response													biological_process											owl:Class	
GO:0015371	biolink:NamedThing	galactose:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).	got7fsn_ti														molecular_function											owl:Class	
GO:0033665	biolink:NamedThing	obsolete regulation of growth or development of symbiont in host	OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.	got7fsn_ti	modulation of growth or development of organism within host|modulation of invasive growth|regulation of growth or development of symbiont in host|modulation of growth or development of symbiont within host|regulation of growth or development of symbiont within host				This term was made obsolete because it contained a conjunction (or).	GO:0044127				True				biological_process											owl:Class	
GO:0030207	biolink:NamedThing	chondroitin sulfate catabolic process	The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.	got7fsn_ti	chondroitin sulfate catabolism|chondroitin sulfate breakdown|chondroitin sulphate catabolism|chondroitin sulfate degradation|chondroitin sulphate catabolic process													biological_process											owl:Class	
GO:0002857	biolink:NamedThing	positive regulation of natural killer cell mediated immune response to tumor cell	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.	got7fsn_ti	up regulation of natural killer cell mediated immune response to tumor cell|up-regulation of natural killer cell mediated immune response to tumor cell|activation of natural killer cell mediated immune response to tumor cell|stimulation of natural killer cell mediated immune response to tumor cell|upregulation of natural killer cell mediated immune response to tumor cell													biological_process											owl:Class	
GO:0070292	biolink:NamedThing	N-acylphosphatidylethanolamine metabolic process	The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.	got7fsn_ti	N-acylphosphatidylethanolamine metabolism|NAPE metabolism|NAPE metabolic process													biological_process											owl:Class	
GO:2001072	biolink:NamedThing	galactomannan binding	Binding to galactomannan.	got7fsn_ti							jl	2011-09-14T12:12:02Z						molecular_function											owl:Class	
GO:0019258	biolink:NamedThing	4-nitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene.	got7fsn_ti	4-nitrotoluene degradation|4NT catabolic process|4NT catabolism|4-nitrotoluene catabolism|4-nitrotoluene breakdown											MetaCyc:P421-PWY		biological_process											owl:Class	
GO:2000002	biolink:NamedThing	negative regulation of DNA damage checkpoint	Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint.	got7fsn_ti	negative regulation of DNA damage response, signal transduction resulting in cell cycle arrest						jl	2010-07-15T03:25:06Z						biological_process											owl:Class	
GO:2001306	biolink:NamedThing	lipoxin B4 biosynthetic process	The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.	got7fsn_ti	LXB4 biosynthesis|lipoxin B4 biosynthesis|lipoxin B4 formation|LXB4 synthesis|LXB4 anabolism|LXB4 formation|lipoxin B4 synthesis|lipoxin B4 anabolism|LXB4 biosynthetic process						bf	2012-03-07T11:15:04Z						biological_process											owl:Class	
GO:0023012	biolink:NamedThing	obsolete initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor	OBSOLETE. The process in which binding of an MHC complex to T cell receptor causes activation of T cell receptor signaling.	got7fsn_ti	initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor|initiation of T cell receptor signalling by binding of a MHC complex to T cell receptor				This term was made obsolete because it is describing a binding molecular function.	GO:0050852|GO:0042101		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
CHEBI:17272	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043535	biolink:NamedThing	regulation of blood vessel endothelial cell migration	Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.	got7fsn_ti														biological_process											owl:Class	
GO:1904102	biolink:NamedThing	cellular response to acadesine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.	got7fsn_ti							mr	2015-03-30T22:36:32Z						biological_process											owl:Class	
GO:1901844	biolink:NamedThing	regulation of cell communication by electrical coupling involved in cardiac conduction	Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.	got7fsn_ti							rl	2013-01-24T19:15:39Z						biological_process											owl:Class	
GO:2000897	biolink:NamedThing	amylopectin catabolic process	The chemical reactions and pathways resulting in the breakdown of an amylopectin.	got7fsn_ti	Amylopectin catabolism						jl	2011-07-28T02:47:28Z						biological_process											owl:Class	
GO:1905263	biolink:NamedThing	positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.	got7fsn_ti	up-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|upregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|up regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|activation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination						se	2016-06-13T20:45:18Z						biological_process											owl:Class	
GO:2001302	biolink:NamedThing	lipoxin A4 metabolic process	The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.	got7fsn_ti	LXA4 metabolic process|lipoxin A4 metabolism|LXA4 metabolism						bf	2012-03-07T11:13:12Z						biological_process											owl:Class	
GO:0039608	biolink:NamedThing	obsolete suppression by virus of host translation initiation factor activity by induction of host protein dephosphorylation	OBSOLETE. Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor by promoting dephosphorylation of a host protein.	got7fsn_ti					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-07-06T10:30:57Z		True				biological_process											owl:Class	
GO:0001144	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015406	biolink:NamedThing	obsolete ABC-type uptake permease activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	ABC-type uptake permease activity				This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.	GO:0042626|GO:0043190				True				molecular_function											owl:Class	
CHEBI:9973	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090259	biolink:NamedThing	regulation of retinal ganglion cell axon guidance	Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.	got7fsn_ti							tb	2010-02-03T04:13:59Z						biological_process											owl:Class	
GO:1902258	biolink:NamedThing	positive regulation of apoptotic process involved in outflow tract morphogenesis	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.	got7fsn_ti	up-regulation of apoptotic process involved in outflow tract morphogenesis|positive regulation of apoptosis involved in outflow tract morphogenesis|upregulation of apoptotic process involved in outflow tract morphogenesis|activation of apoptosis involved in outflow tract morphogenesis|upregulation of apoptosis involved in outflow tract morphogenesis|up regulation of apoptosis involved in outflow tract morphogenesis|up regulation of apoptotic process involved in outflow tract morphogenesis|up-regulation of apoptosis involved in outflow tract morphogenesis|activation of apoptotic process involved in outflow tract morphogenesis						dph	2013-06-24T19:12:42Z						biological_process											owl:Class	
GO:0015843	biolink:NamedThing	methylammonium transport	The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0033033	biolink:NamedThing	negative regulation of myeloid cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.	got7fsn_ti	negative regulation of myeloid cell apoptosis|down regulation of myeloid cell apoptosis|inhibition of myeloid cell apoptosis|down-regulation of myeloid cell apoptosis|downregulation of myeloid cell apoptosis													biological_process											owl:Class	
GO:0005953	biolink:NamedThing	CAAX-protein geranylgeranyltransferase complex	A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0050434	biolink:NamedThing	positive regulation of viral transcription	Any process that activates or increases the frequency, rate or extent of viral transcription.	got7fsn_ti	up regulation of viral transcription|up-regulation of viral transcription|activation of viral transcription|stimulation of viral transcription|upregulation of viral transcription													biological_process											owl:Class	
CHEBI:17256	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009168	biolink:NamedThing	purine ribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine ribonucleoside monophosphate anabolism|purine ribonucleoside monophosphate formation|purine ribonucleoside monophosphate synthesis|purine ribonucleoside monophosphate biosynthesis													biological_process											owl:Class	
GO:0098991	biolink:NamedThing	kainate selective glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti														biological_process											owl:Class	
GO:0090407	biolink:NamedThing	organophosphate biosynthetic process	The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.	got7fsn_ti							tb	2011-02-26T02:22:41Z						biological_process											owl:Class	
GO:0033400	biolink:NamedThing	trans-zeatin metabolic process	The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	got7fsn_ti	trans-zeatin metabolism													biological_process											owl:Class	
GO:0099107	biolink:NamedThing	ion channel regulator activity involved in G protein-coupled receptor signaling pathway	Modulation of the activity of an ion channel via direct interaction with it as part of G protein-coupled receptor signaling.	got7fsn_ti	ion channel regulator activity involved in G-protein coupled receptor signaling pathway													molecular_function											owl:Class	
GO:1901608	biolink:NamedThing	regulation of vesicle transport along microtubule	Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.	got7fsn_ti	regulation of microtubule-based vesicle localization						hjd	2012-11-08T21:49:44Z						biological_process											owl:Class	
GO:0061475	biolink:NamedThing	cytosolic valyl-tRNA aminoacylation	The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	got7fsn_ti							dph	2012-11-06T12:29:42Z						biological_process											owl:Class	
GO:0010156	biolink:NamedThing	obsolete sporocyte morphogenesis	OBSOLETE. Formation and development of sporocyte, the haploid spores of angiosperms which are initiated by the differentiation of a subset of floral cells into sporocytes, which then undergo meiotic divisions to form microspores and megaspores.	got7fsn_ti	sporocyte morphogenesis				This term was made obsolete because it was incorrectly defined.	GO:0048533				True				biological_process											owl:Class	
GO:0055032	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008438	biolink:NamedThing	obsolete 1-phosphatidylinositol-5-phosphate kinase	OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide.	got7fsn_ti	1-phosphatidylinositol-5-phosphate kinase				This term was made obsolete because it is a redundant grouping term with only one child. It is also incorrectly defined and had an incorrect EC dbxref.	GO:0016309				True				molecular_function											owl:Class	
CHEBI:63709	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003385	biolink:NamedThing	cell-cell signaling involved in amphid sensory organ development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state.	got7fsn_ti	cell-cell signalling involved in amphid sensory organ development						dph	2009-12-09T08:55:37Z						biological_process											owl:Class	
GO:0060593	biolink:NamedThing	Wnt signaling pathway involved in mammary gland specification	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.	got7fsn_ti	Wnt receptor signalling pathway involved in mammary gland specification|Wnt receptor signaling pathway involved in mammary gland specification|Wnt-activated signaling pathway involved in mammary gland specification						dph	2009-05-13T09:41:37Z						biological_process											owl:Class	
GO:0010664	biolink:NamedThing	negative regulation of striated muscle cell apoptotic process	Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.	got7fsn_ti	inhibition of striated muscle cell apoptosis|downregulation of striated muscle cell apoptosis|down-regulation of striated muscle cell apoptosis|down regulation of striated muscle cell apoptosis|negative regulation of striated muscle cell apoptosis													biological_process											owl:Class	
GO:0098901	biolink:NamedThing	regulation of cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti														biological_process											owl:Class	
CHEBI:37592	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25703	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052236	biolink:NamedThing	obsolete negative chemotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	negative chemotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
CHEBI:26349	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002290	biolink:NamedThing	gamma-delta T cell activation involved in immune response	The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	gamma-delta T lymphocyte activation during immune response|gamma-delta T cell activation during immune response|gamma-delta T-lymphocyte activation during immune response|gamma-delta T-cell activation during immune response													biological_process											owl:Class	
GO:0039659	biolink:NamedThing	obsolete suppression by virus of host TBK1-IKBKE-DDX3 complex activity	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TBK1-IKBKE-DDX3 complex.	got7fsn_ti	suppression by virus of host TBK1-IKKE-DDX3 complex activity|inhibition of host TBK1-IKBKE-DDX3 complex by virus				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. See also: suppression by virus of host TBK1 activity; GO:0039723, and suppression by virus of host IKBKE activity; GO:0039724.		bf	2013-07-15T15:10:39Z		True		VZ:719		biological_process											owl:Class	
CHEBI:57336	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099540	biolink:NamedThing	trans-synaptic signaling by neuropeptide	Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft.	got7fsn_ti														biological_process											owl:Class	
CHEBI:16450	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009142	biolink:NamedThing	nucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	nucleoside triphosphate synthesis|nucleoside triphosphate biosynthesis|nucleoside triphosphate anabolism|nucleoside triphosphate formation													biological_process											owl:Class	
GO:0001128	biolink:NamedThing	obsolete RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly	OBSOLETE. Binding to an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or stability of the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC). Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery.	got7fsn_ti	RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly				This term was obsoleted because it represented a mix of function and process and is not annotated consistently		krc	2011-01-20T02:13:36Z		True				molecular_function											owl:Class	
GO:1903230	biolink:NamedThing	obsolete miRNA binding involved in posttranscriptional gene silencing	OBSOLETE. Any miRNA binding that is involved in posttranscriptional gene silencing.	got7fsn_ti	miRNA binding involved in posttranscriptional gene silencing|miRNA binding involved in quelling|miRNA binding involved in post-transcriptional gene silencing|microRNA binding involved in post-transcriptional gene silencing|miRNA binding involved in PTGS|microRNA binding involved in posttranscriptional gene silencing|microRNA binding involved in PTGS|microRNA binding involved in quelling|miRNA binding involved in cosuppression|microRNA binding involved in cosuppression				This term was obsoleted at the TermGenie Gatekeeper stage.		jl	2014-07-31T10:22:18Z		True				molecular_function											owl:Class	
GO:0002661	biolink:NamedThing	regulation of B cell tolerance induction	Any process that modulates the frequency, rate, or extent of B cell tolerance induction.	got7fsn_ti	regulation of B lymphocyte tolerance induction|regulation of B-cell tolerance induction|regulation of B-lymphocyte tolerance induction													biological_process											owl:Class	
UBERON:0000207	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090271	biolink:NamedThing	positive regulation of fibroblast growth factor production	Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti							tb	2010-02-05T02:33:33Z						biological_process											owl:Class	
GO:0052554	biolink:NamedThing	obsolete modulation by organism of symbiont immune response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0019493	biolink:NamedThing	arginine catabolic process to proline	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline.	got7fsn_ti	arginine degradation to proline|arginine breakdown to proline											MetaCyc:ARG-PRO-PWY		biological_process											owl:Class	
GO:0045825	biolink:NamedThing	obsolete negative regulation of intermediate filament polymerization and/or depolymerization	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization and/or depolymerization.	got7fsn_ti	negative regulation of intermediate filament polymerization and/or depolymerization				This term was made obsolete because it has been split.	GO:0030843|GO:0030840				True				biological_process											owl:Class	
GO:0046171	biolink:NamedThing	octanol biosynthetic process	The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH.	got7fsn_ti	octanol formation|octanol biosynthesis|octanol anabolism|octanol synthesis													biological_process											owl:Class	
GO:0062246	biolink:NamedThing	exocytic vesicle lumen	The volume enclosed by an exocytic vesicle.	got7fsn_ti							dph	2020-04-27T12:10:09Z						cellular_component											owl:Class	
GO:0021865	biolink:NamedThing	obsolete symmetric radial glial cell division in forebrain	OBSOLETE. The mitotic division of a radial glial cell giving rise to two new radial glial cells in the forebrain.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:1904903	biolink:NamedThing	ESCRT III complex disassembly	The disaggregation of an ESCRT III complex into its constituent components.	got7fsn_ti							pad	2016-01-18T13:38:14Z						biological_process											owl:Class	
CHEBI:33184	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903480	biolink:NamedThing	regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti	regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly						vw	2014-09-23T16:03:42Z						biological_process											owl:Class	
GO:1901660	biolink:NamedThing	calcium ion export	The directed movement of calcium ion out of a cell or organelle.	got7fsn_ti							jl	2012-11-20T14:33:07Z						biological_process											owl:Class	
GO:0018956	biolink:NamedThing	phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite.	got7fsn_ti	phenanthrene breakdown via trans-9(R),10(R)-dihydrodiolphenanthrene|phenanthrene degradation via trans-9(R),10(R)-dihydrodiolphenanthrene											UM-BBD_pathwayID:pha3		biological_process											owl:Class	
CL:0000893	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901702	biolink:NamedThing	salt transmembrane transporter activity	Enables the transfer of salt from one side of a membrane to the other.	got7fsn_ti							pr	2012-12-13T15:14:47Z						molecular_function											owl:Class	
GO:2001186	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta T cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.	got7fsn_ti							yaf	2011-11-03T01:16:57Z						biological_process											owl:Class	
GO:0052935	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015429	biolink:NamedThing	obsolete peroxisomal fatty acyl transporter	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peroxisomal fatty acyl transporter				This term was made obsolete because it describes a gene product and it contains both component and function information.					True				molecular_function											owl:Class	
GO:0002705	biolink:NamedThing	positive regulation of leukocyte mediated immunity	Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.	got7fsn_ti	activation of leukocyte mediated immunity|positive regulation of leucocyte mediated immunity|up-regulation of leukocyte mediated immunity|up regulation of leukocyte mediated immunity|upregulation of leukocyte mediated immunity|positive regulation of immune cell mediated immunity|stimulation of leukocyte mediated immunity													biological_process											owl:Class	
GO:0051106	biolink:NamedThing	positive regulation of DNA ligation	Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.	got7fsn_ti	activation of DNA ligation|stimulation of DNA ligation|up regulation of DNA ligation|upregulation of DNA ligation|up-regulation of DNA ligation													biological_process											owl:Class	
GO:0008510	biolink:NamedThing	sodium:bicarbonate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).	got7fsn_ti	sodium:bicarbonate cotransporter activity|sodium/bicarbonate cotransporter activity											Reactome:R-HSA-8878664|Reactome:R-HSA-425483|Reactome:R-HSA-5656219		molecular_function											owl:Class	
PO:0025262	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902568	biolink:NamedThing	positive regulation of eosinophil activation	Any process that activates or increases the frequency, rate or extent of eosinophil activation.	got7fsn_ti	activation of eosinophil activation|upregulation of eosinophil activation|up-regulation of eosinophil activation|up regulation of eosinophil activation						ecu	2013-12-10T15:54:52Z						biological_process											owl:Class	
UBERON:0009773	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006018	biolink:NamedThing	2-deoxyribose 1-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.	got7fsn_ti	2-deoxyribose 1-phosphate degradation|deoxyribose 1-phosphate catabolic process|2-deoxyribose 1-phosphate catabolism|2-deoxyribose 1-phosphate breakdown													biological_process											owl:Class	
GO:0003801	biolink:NamedThing	obsolete blood coagulation factor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	blood coagulation factor activity				This term was made obsolete because it refers to involvement in a biological process.	GO:0004252|GO:0007596				True				molecular_function											owl:Class	
CHEBI:26400	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003914	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071437	biolink:NamedThing	obsolete invadopodium	OBSOLETE. A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate.	got7fsn_ti					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		mah	2009-12-16T02:19:58Z		True				cellular_component											owl:Class	
GO:0062228	biolink:NamedThing	negative regulation of adult somatic muscle development	Any process that decreases the rate, frequency or extent of adult somatic muscle development.	got7fsn_ti							dph	2020-03-16T13:34:38Z						biological_process											owl:Class	
UBERON:0005569	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019024	biolink:NamedThing	obsolete ssRNA viral genome	OBSOLETE. A viral genome composed of single stranded RNA of either positive or negative sense.	got7fsn_ti					This term was obsoleted because it does not represent a GO cellular component.					True				cellular_component											owl:Class	
GO:0015917	biolink:NamedThing	aminophospholipid transport	The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.	got7fsn_ti														biological_process											owl:Class	
GO:0051540	biolink:NamedThing	metal cluster binding	Binding to a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters.	got7fsn_ti														molecular_function											owl:Class	
GO:1901901	biolink:NamedThing	regulation of protein localization to cell division site involved in cytokinesis	Any regulation of protein localization to cell division site that is involved in cytokinesis.	got7fsn_ti	regulation of protein localisation to cell division site involved in cytokinesis						dph	2013-02-12T18:01:34Z						biological_process											owl:Class	
GO:2000019	biolink:NamedThing	negative regulation of male gonad development	Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.	got7fsn_ti	negative regulation of testicular development|negative regulation of testis development						jl	2010-07-15T03:29:10Z						biological_process											owl:Class	
GO:2000032	biolink:NamedThing	regulation of secondary shoot formation	Any process that modulates the frequency, rate or extent of secondary shoot formation.	got7fsn_ti	regulation of shoot branching|regulation of auxiliary shoot formation|regulation of axillary shoot system formation|regulation of axillary shoot formation						tb	2010-08-05T11:32:50Z						biological_process											owl:Class	
GO:0005321	biolink:NamedThing	obsolete high-density lipoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	HDL|high-density lipoprotein			GO:0005319	This term was made obsolete because it does not represent a molecular function.					True				molecular_function											owl:Class	
GO:1905457	biolink:NamedThing	negative regulation of lymphoid progenitor cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation.	got7fsn_ti	down-regulation of lymphoid progenitor cell differentiation|inhibition of lymphoid progenitor cell differentiation|downregulation of lymphoid progenitor cell differentiation|down regulation of lymphoid progenitor cell differentiation						rz	2016-09-16T12:32:48Z						biological_process											owl:Class	
GO:0003673	biolink:NamedThing	obsolete Gene_Ontology	OBSOLETE. A controlled vocabulary that can be applied to all organisms even as knowledge of gene and protein roles in cells is accumulating and changing. GO provides three structured networks of defined terms to describe gene product attributes.	got7fsn_ti	Gene_Ontology				This term was made obsolete because more specific terms were created.					True				biological_process											owl:Class	
GO:0075185	biolink:NamedThing	positive regulation of infection cushion formation	Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of infection cushion formation on or near host													biological_process											owl:Class	
GO:0140016	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033393	biolink:NamedThing	homogalacturonan catabolic process	The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.	got7fsn_ti	homogalacturonan breakdown|homogalacturonan degradation|homogalacturonan catabolism											MetaCyc:PWY-1081		biological_process											owl:Class	
GO:0106072	biolink:NamedThing	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.	got7fsn_ti	negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway						hjd	2017-11-28T18:41:31Z						biological_process											owl:Class	
GO:0034442	biolink:NamedThing	regulation of lipoprotein oxidation	Any process that modulates the frequency, rate or extent of lipoprotein oxidation.	got7fsn_ti														biological_process											owl:Class	
GO:1904639	biolink:NamedThing	cellular response to resveratrol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.	got7fsn_ti							sl	2015-08-31T17:07:44Z						biological_process											owl:Class	
GO:0046130	biolink:NamedThing	purine ribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.	got7fsn_ti	purine ribonucleoside catabolism|purine ribonucleoside degradation|purine ribonucleoside breakdown													biological_process											owl:Class	
GO:0052229	biolink:NamedThing	obsolete metabolism of macromolecule in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism of macromolecule in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:1902883	biolink:NamedThing	negative regulation of response to oxidative stress	Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress.	got7fsn_ti	down regulation of response to oxidative stress|downregulation of response to oxidative stress|down-regulation of response to oxidative stress|inhibition of response to oxidative stress						kmv	2014-04-03T20:30:20Z						biological_process											owl:Class	
GO:1901737	biolink:NamedThing	(R)-mevalonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid.	got7fsn_ti	(R)-mevalonate anabolism|(R)-mevalonate synthesis|(R)-mevalonic acid formation|(R)-mevalonic acid anabolism|(R)-mevalonate biosynthesis|(R)-mevalonic acid biosynthesis|(R)-mevalonic acid synthesis						yaf	2013-01-11T11:25:59Z						biological_process											owl:Class	
GO:2000672	biolink:NamedThing	negative regulation of motor neuron apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process.	got7fsn_ti	negative regulation of motoneuron apoptosis|negative regulation of motor neuron apoptosis						pr	2011-05-09T10:56:21Z						biological_process											owl:Class	
GO:0045493	biolink:NamedThing	xylan catabolic process	The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.	got7fsn_ti	xylan breakdown|xylan catabolism|xylan degradation													biological_process											owl:Class	
GO:0072303	biolink:NamedThing	positive regulation of glomerular metanephric mesangial cell proliferation	Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.	got7fsn_ti							mah	2010-04-09T05:03:41Z						biological_process											owl:Class	
UBERON:0001032	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904448	biolink:NamedThing	regulation of aspartate secretion	Any process that modulates the frequency, rate or extent of aspartate secretion.	got7fsn_ti							sl	2015-07-07T20:56:57Z						biological_process											owl:Class	
CHEBI:25155	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019624	biolink:NamedThing	atrazine catabolic process to isopropylamine	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine.	got7fsn_ti	atrazine breakdown to isopropylamine|atrazine degradation to isopropylamine													biological_process											owl:Class	
GO:2000219	biolink:NamedThing	positive regulation of invasive growth in response to glucose limitation	Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation.	got7fsn_ti	positive regulation of colony morphology						mah	2010-11-03T04:36:02Z						biological_process											owl:Class	
GO:1903924	biolink:NamedThing	estradiol binding	Binding to estradiol.	got7fsn_ti							sl	2015-02-11T00:11:34Z						molecular_function											owl:Class	
GO:0042346	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045708	biolink:NamedThing	regulation of larval salivary gland boundary specification	Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism.	got7fsn_ti	regulation of larval salivary gland determination													biological_process											owl:Class	
GO:0080051	biolink:NamedThing	cutin transport	The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface.	got7fsn_ti														biological_process											owl:Class	
GO:0003392	biolink:NamedThing	cell adhesion involved in retrograde extension	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension.	got7fsn_ti							dph	2009-12-09T09:32:06Z						biological_process											owl:Class	
GO:0062064	biolink:NamedThing	box C/D snoRNP complex binding	Binding to a box C/D snoRNP complex.	got7fsn_ti							dph	2018-08-31T14:01:03Z						molecular_function											owl:Class	
GO:0015118	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008525	biolink:NamedThing	phosphatidylcholine transporter activity	Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	got7fsn_ti	phosphatidylcholine transmembrane transporter activity													molecular_function											owl:Class	
GO:0075190	biolink:NamedThing	negative regulation of hyphopodium formation	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation of hyphopodium formation on or near host													biological_process											owl:Class	
GO:0046501	biolink:NamedThing	protoporphyrinogen IX metabolic process	The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.	got7fsn_ti	protoporphyrinogen IX metabolism				See also the molecular function term 'ferrochelatase activity ; GO:0004325'.									biological_process											owl:Class	
CHEBI:34892	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046343	biolink:NamedThing	streptomycin metabolic process	The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.	got7fsn_ti	streptomycin metabolism													biological_process											owl:Class	
GO:0060558	biolink:NamedThing	regulation of calcidiol 1-monooxygenase activity	Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.	got7fsn_ti							dph	2009-04-13T02:52:18Z						biological_process											owl:Class	
GO:0110094	biolink:NamedThing	polyphosphate-mediated signaling	Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.	got7fsn_ti	polyphosphate signaling						kmv	2018-02-15T16:42:30Z						biological_process											owl:Class	
GO:0035998	biolink:NamedThing	7,8-dihydroneopterin 3'-triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate.	got7fsn_ti	7,8-dihydroneopterin 3'-triphosphate formation|7,8-dihydroneopterin 3'-triphosphate synthesis|7,8-dihydroneopterin 3'-triphosphate anabolism|7,8-dihydroneopterin 3'-triphosphate biosynthesis						bf	2011-09-02T01:15:35Z				UniPathway:UPA00848		biological_process											owl:Class	
GO:0033864	biolink:NamedThing	positive regulation of NAD(P)H oxidase activity	Any process that activates or increases the activity of the enzyme NAD(P)H oxidase.	got7fsn_ti	stimulation of NAD(P)H oxidase activity|upregulation of NAD(P)H oxidase activity|activation of NAD(P)H oxidase activity|up-regulation of NAD(P)H oxidase activity|up regulation of NAD(P)H oxidase activity													biological_process											owl:Class	
GO:0044133	biolink:NamedThing	obsolete growth of symbiont on or near host	OBSOLETE. The increase in size or mass of a symbiont within the cells or tissues of its host organism.	got7fsn_ti					This term was obsoleted because it represented both a process and a location.		jl	2009-08-04T03:36:49Z		True				biological_process											owl:Class	
GO:0033860	biolink:NamedThing	regulation of NAD(P)H oxidase activity	Any process that modulates the activity of the enzyme NAD(P)H oxidase.	got7fsn_ti														biological_process											owl:Class	
GO:1904556	biolink:NamedThing	L-tryptophan transmembrane transport	The directed movement of L-tryptophan across a membrane.	got7fsn_ti							pr	2015-08-14T14:21:13Z						biological_process											owl:Class	
SO:0001997	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26440	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006004	biolink:NamedThing	fucose metabolic process	The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose.	got7fsn_ti	fucose metabolism													biological_process											owl:Class	
PO:0020042	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008004	biolink:NamedThing	obsolete lamina reticularis	OBSOLETE. A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue.	got7fsn_ti				GO:0005604	This term was obsoleted because as a layer of the basement membrane, the lamina reticularis is thought to be an artefact. See PMID:24137544 and PMID:8061357.					True				cellular_component											owl:Class	
GO:1905452	biolink:NamedThing	obsolete canonical Wnt signaling pathway involved in regulation of stem cell proliferation	OBSOLETE. Any canonical Wnt signaling pathway that is involved in regulation of stem cell proliferation.	got7fsn_ti	Wnt receptor signaling pathway via beta-catenin involved in regulation of stem cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of stem cell proliferation|frizzled-1 receptor signaling pathway involved in regulation of stem cell proliferation|Wnt receptor signaling pathway through beta-catenin involved in regulation of stem cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of stem cell proliferation|Wnt receptor signalling pathway through beta-catenin involved in regulation of stem cell proliferation				This term was obsoleted at the TermGenie Gatekeeper stage.		bc	2016-09-16T11:52:42Z		True				biological_process											owl:Class	
GO:1901784	biolink:NamedThing	p-cresol metabolic process	The chemical reactions and pathways involving p-cresol.	got7fsn_ti	p-cresol metabolism						yaf	2013-01-16T11:03:59Z						biological_process											owl:Class	
CHEBI:64161	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000105	biolink:NamedThing	histidine biosynthetic process	The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	got7fsn_ti	histidine anabolism|histidine biosynthesis|histidine synthesis|histidine formation											MetaCyc:HISTSYN-PWY		biological_process											owl:Class	
GO:1904248	biolink:NamedThing	regulation of age-related resistance	Any process that modulates the extent of age-related resistance.	got7fsn_ti	regulation of adult seedling resistance|regulation of flowering-induced resistance|regulation of mature seedling resistance|regulation of ARR|regulation of senescence-induced resistance|regulation of ontogenic resistance|regulation of developmental resistance						tb	2015-05-19T20:19:58Z						biological_process											owl:Class	
GO:2000504	biolink:NamedThing	positive regulation of blood vessel remodeling	Any process that activates or increases the frequency, rate or extent of blood vessel remodeling.	got7fsn_ti							pr	2011-03-21T10:33:20Z						biological_process											owl:Class	
GO:0033159	biolink:NamedThing	obsolete negative regulation of protein import into nucleus, translocation	OBSOLETE. Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.	got7fsn_ti	negative regulation of protein import into cell nucleus, translocation				This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True				biological_process											owl:Class	
GO:1901822	biolink:NamedThing	delta-carotene metabolic process	The chemical reactions and pathways involving delta-carotene.	got7fsn_ti	delta-carotene metabolism						yaf	2013-01-22T11:17:29Z						biological_process											owl:Class	
GO:0046251	biolink:NamedThing	limonene catabolic process	The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.	got7fsn_ti	limonene degradation|limonene catabolism|limonene breakdown													biological_process											owl:Class	
GO:0042173	biolink:NamedThing	regulation of sporulation resulting in formation of a cellular spore	Any process that modulates the frequency, rate or extent of spore formation.	got7fsn_ti														biological_process											owl:Class	
GO:0052365	biolink:NamedThing	obsolete catabolism by host of symbiont xylan	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because there is no evidence it exists.					True				biological_process											owl:Class	
CHEBI:60272	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25646	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902290	biolink:NamedThing	positive regulation of defense response to oomycetes	Any process that activates or increases the frequency, rate or extent of defense response to oomycetes.	got7fsn_ti	activation of defense response to oomycetes|upregulation of defense response to oomycetes|up-regulation of defense response to oomycetes|up regulation of defense response to oomycetes						ms	2013-07-09T13:45:43Z						biological_process											owl:Class	
OBO:GOCHE_35195	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000560	biolink:NamedThing	positive regulation of CD24 production	Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process.	got7fsn_ti	positive regulation of CD24 biosynthesis|positive regulation of CD24 biosynthetic process|positive regulation of CD24 formation|positive regulation of CD24 synthesis|positive regulation of CD24 anabolism						ebc	2011-04-03T08:57:02Z						biological_process											owl:Class	
GO:0070070	biolink:NamedThing	proton-transporting V-type ATPase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.	got7fsn_ti	V-ATPase assembly|V-ATPase complex assembly													biological_process											owl:Class	
UBERON:0006544	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072204	biolink:NamedThing	cell-cell signaling involved in metanephros development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.	got7fsn_ti	cell-cell signalling involved in metanephros development						mah	2010-03-18T10:54:36Z						biological_process											owl:Class	
GO:0055050	biolink:NamedThing	astral spindle assembly involved in male meiosis	The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells.	got7fsn_ti														biological_process											owl:Class	
GO:1902925	biolink:NamedThing	poly(hydroxyalkanoate) biosynthetic process from fatty acid	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid.	got7fsn_ti	poly(hydroxyalkanoate) biosynthesis from fatty acid|poly(hydroxyalkanoate) anabolism from fatty acid|poly(hydroxyalkanoate) synthesis from fatty acid|poly(hydroxyalkanoate) formation from fatty acid						tt	2014-04-21T22:53:59Z						biological_process											owl:Class	
GO:1990952	biolink:NamedThing	obsolete manchette disassembly	OBSOLETE. A cellular process that results in the breakdown of a manchette.	got7fsn_ti	manchette clearance				This term was obsoleted at the TermGenie Gatekeeper stage.		krc	2016-05-11T00:14:16Z		True				biological_process											owl:Class	
GO:0051951	biolink:NamedThing	positive regulation of glutamate uptake involved in transmission of nerve impulse	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.	got7fsn_ti	positive regulation of glutamate uptake involved in conduction of nerve impulse|activation of glutamate uptake during transmission of nerve impulse|upregulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate reuptake|up regulation of glutamate uptake during transmission of nerve impulse|stimulation of glutamate uptake during transmission of nerve impulse|up-regulation of glutamate uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0106121	biolink:NamedThing	positive regulation of cobalamin metabolic process	Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.	got7fsn_ti							hjd	2018-05-01T18:07:12Z						biological_process											owl:Class	
GO:1903461	biolink:NamedThing	Okazaki fragment processing involved in mitotic DNA replication	Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication.	got7fsn_ti	DNA replication, Okazaki fragment processing involved in DNA replication during S phase involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in mitotic nuclear cell cycle DNA replication|DNA replication, Okazaki fragment processing involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in DNA replication involved in S phase involved in mitotic cell cycle						vw	2014-09-23T13:33:11Z						biological_process											owl:Class	
GO:0070908	biolink:NamedThing	tyrosine:tyramine antiporter activity	Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out).	got7fsn_ti	tyrosine/tyramine antiporter activity|tyrosine-tyramine antiporter activity						mah	2009-09-04T03:49:45Z						molecular_function											owl:Class	
GO:1901882	biolink:NamedThing	4-hydroxycoumarin metabolic process	The chemical reactions and pathways involving 4-hydroxycoumarin.	got7fsn_ti	4-hydroxycoumarin metabolism						ms	2013-02-06T14:05:50Z						biological_process											owl:Class	
GO:1904273	biolink:NamedThing	L-alanine import across plasma membrane	The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol.	got7fsn_ti														biological_process											owl:Class	
CHEBI:24279	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034051	biolink:NamedThing	negative regulation of plant-type hypersensitive response	Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.	got7fsn_ti	negative regulation of HR-PCD|downregulation of plant-type hypersensitive response|inhibition of plant-type hypersensitive response|down-regulation of plant-type hypersensitive response|negative regulation of HR|negative regulation of plant hypersensitive response|down regulation of plant-type hypersensitive response													biological_process											owl:Class	
GO:1901778	biolink:NamedThing	pentalenolactone metabolic process	The chemical reactions and pathways involving pentalenolactone.	got7fsn_ti	pentalenolactone metabolism						yaf	2013-01-16T09:49:38Z						biological_process											owl:Class	
UBERON:0001235	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046803	biolink:NamedThing	obsolete reduction of virulence	OBSOLETE. Any process that stops, prevents or reduces the severity of viral infection and subsequent disease.	got7fsn_ti	reduction of virulence				This term was made obsolete because 'virulence' is not a biological process; however, alteration of virulence also does not fit under 'regulation of biological quality ; GO:0065008' because it is a product both of the genotype/phenotype of the infecting organism and the genotype/phenotype of the organism being infected and varies by individual within a species both for the infecting organism and the infected organism.					True				biological_process											owl:Class	
GO:0090098	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902762	biolink:NamedThing	regulation of embryonic skeletal joint development	Any process that modulates the frequency, rate or extent of embryonic skeletal joint development.	got7fsn_ti							mr	2014-03-07T17:46:01Z						biological_process											owl:Class	
GO:1901013	biolink:NamedThing	3alpha(S)-strictosidine metabolic process	The chemical reactions and pathways involving 3alpha(S)-strictosidine.	got7fsn_ti	3alpha(S)-strictosidine metabolism						yaf	2012-06-15T10:46:57Z						biological_process											owl:Class	
GO:2000377	biolink:NamedThing	regulation of reactive oxygen species metabolic process	Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.	got7fsn_ti	regulation of ROS metabolic process|regulation of reactive oxygen species metabolism						mah	2011-02-11T02:06:36Z						biological_process											owl:Class	
UBERON:0000995	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000178	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030442	biolink:NamedThing	obsolete inactivation of MAPK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	inactivation of MAPK during sporulation (sensu Fungi)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
GO:0031227	biolink:NamedThing	intrinsic component of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to endoplasmic reticulum membrane													cellular_component											owl:Class	
GO:0007122	biolink:NamedThing	obsolete loss of asymmetric budding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	loss of asymmetric budding				This term was made obsolete because it is a phenotype rather than a biological process.	GO:0006033				True				biological_process											owl:Class	
CHEBI:82706	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64962	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009674	biolink:NamedThing	potassium:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in).	got7fsn_ti	high affinity potassium transporter													molecular_function											owl:Class	
GO:2001017	biolink:NamedThing	regulation of retrograde axon cargo transport	Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.	got7fsn_ti	regulation of retrograde axonal transport						kmv	2011-08-11T09:44:42Z						biological_process											owl:Class	
GO:1900890	biolink:NamedThing	regulation of pentadecane metabolic process	Any process that modulates the frequency, rate or extent of pentadecane metabolic process.	got7fsn_ti	regulation of pentadecane metabolism						tt	2012-06-13T03:05:48Z						biological_process											owl:Class	
GO:0002763	biolink:NamedThing	positive regulation of myeloid leukocyte differentiation	Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.	got7fsn_ti	activation of myeloid leukocyte differentiation|up regulation of myeloid leukocyte differentiation|upregulation of myeloid leukocyte differentiation|up-regulation of myeloid leukocyte differentiation|stimulation of myeloid leukocyte differentiation													biological_process											owl:Class	
GO:0099058	biolink:NamedThing	integral component of postsynaptic endocytic zone membrane	The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:2000123	biolink:NamedThing	positive regulation of stomatal complex development	Any process that activates or increases the frequency, rate or extent of stomatal complex development.	got7fsn_ti							dhl	2010-09-27T08:28:28Z						biological_process											owl:Class	
GO:1904691	biolink:NamedThing	negative regulation of type B pancreatic cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.	got7fsn_ti	down-regulation of type B pancreatic cell proliferation|downregulation of type B pancreatic cell proliferation|downregulation of pancreatic beta cell proliferation|downregulation of pancreatic B cell proliferation|down-regulation of pancreatic beta cell proliferation|down-regulation of pancreatic B cell proliferation|down regulation of pancreatic beta cell proliferation|down regulation of type B pancreatic cell proliferation|down regulation of pancreatic B cell proliferation|inhibition of pancreatic beta cell proliferation|inhibition of type B pancreatic cell proliferation|negative regulation of pancreatic beta cell proliferation|negative regulation of pancreatic B cell proliferation|inhibition of pancreatic B cell proliferation						sl	2015-09-25T15:23:38Z						biological_process											owl:Class	
GO:0061959	biolink:NamedThing	response to (R)-carnitine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus.	got7fsn_ti	response to L-carnitine						dph	2018-01-19T13:31:39Z						biological_process											owl:Class	
UBERON:0001043	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900282	biolink:NamedThing	regulation of cellobiose catabolic process	Any process that modulates the frequency, rate or extent of cellobiose catabolic process.	got7fsn_ti	regulation of cellobiose catabolism						tt	2012-04-05T12:28:50Z						biological_process											owl:Class	
GO:2000720	biolink:NamedThing	positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.	got7fsn_ti	positive regulation of maintenance of mitotic sister chromatin cohesion at centromere|positive regulation of maintenance of sister chromatin cohesion at centromere at mitosis|positive regulation of maintenance of centromeric mitotic sister chromatin cohesion						mah	2011-06-03T10:41:16Z						biological_process											owl:Class	
GO:0033272	biolink:NamedThing	myo-inositol hexakisphosphate transport	The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	phytate transport													biological_process											owl:Class	
GO:0006048	biolink:NamedThing	UDP-N-acetylglucosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-N-acetylglucosamine formation|UDP-GlcNAc biosynthesis|UDP-N-acetylglucosamine anabolism|UDP-N-acetylglucosamine synthesis|UDP-N-acetylglucosamine biosynthesis|UDP-GlcNAc biosynthetic process											MetaCyc:UDPNAGSYN-PWY		biological_process											owl:Class	
GO:2000676	biolink:NamedThing	positive regulation of type B pancreatic cell apoptotic process	Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.	got7fsn_ti	positive regulation of type B pancreatic cell apoptosis|positive regulation of pancreatic beta cell apoptosis|positive regulation of pancreatic B cell apoptosis						pr	2011-05-09T11:51:15Z						biological_process											owl:Class	
GO:0040023	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901643	biolink:NamedThing	obsolete regulation of tRNA methylation in response to nitrogen starvation	OBSOLETE. Any process that modulates the frequency, rate or extent of tRNA methylation in response to nitrogen starvation.	got7fsn_ti							al	2012-11-16T14:44:08Z		True				biological_process											owl:Class	
GO:0001177	biolink:NamedThing	regulation of transcription open complex formation at RNA polymerase II promoter	Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.	got7fsn_ti	regulation of transcriptional open complex formation at RNA polymerase II promoter						krc	2011-06-20T02:01:18Z						biological_process											owl:Class	
CHEBI:57613	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61993	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:47964	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25676	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905921	biolink:NamedThing	regulation of acetylcholine biosynthetic process	Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process.	got7fsn_ti	regulation of acetylcholine synthesis|regulation of acetylcholine anabolism|regulation of acetylcholine formation|regulation of acetylcholine biosynthesis						bc	2017-02-08T13:08:30Z						biological_process											owl:Class	
GO:1902182	biolink:NamedThing	shoot apical meristem development	The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure.	got7fsn_ti	SAM development|promeristem development|primary shoot meristem development						tb	2013-05-30T23:13:21Z						biological_process											owl:Class	
GO:0043241	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010732	biolink:NamedThing	regulation of protein glutathionylation	Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.	got7fsn_ti	regulation of protein amino acid glutathionylation													biological_process											owl:Class	
CHEBI:65069	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901298	biolink:NamedThing	regulation of hydrogen peroxide-mediated programmed cell death	Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.	got7fsn_ti							vk	2012-08-21T09:44:59Z						biological_process											owl:Class	
GO:0010477	biolink:NamedThing	response to sulfur dioxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:1904728	biolink:NamedThing	positive regulation of replicative senescence	Any process that activates or increases the frequency, rate or extent of replicative senescence.	got7fsn_ti	up-regulation of replicative senescence|upregulation of replicative senescence|activation of replicative senescence|up regulation of replicative senescence						rph	2015-10-14T13:11:37Z						biological_process											owl:Class	
GO:0031306	biolink:NamedThing	intrinsic component of mitochondrial outer membrane	The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to mitochondrial outer membrane													cellular_component											owl:Class	
GO:0006608	biolink:NamedThing	obsolete snRNP protein import into nucleus	OBSOLETE. The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane.	got7fsn_ti	snRNP protein transport from cytoplasm to nucleus|snRNP protein-nucleus import|snRNP protein import into cell nucleus				The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606				True				biological_process											owl:Class	
GO:0060895	biolink:NamedThing	retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord.	got7fsn_ti	retinoic acid receptor signalling pathway involved in spinal cord dorsal/ventral patterning						dph	2009-08-13T01:51:50Z						biological_process											owl:Class	
GO:1904630	biolink:NamedThing	cellular response to diterpene	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.	got7fsn_ti							sl	2015-08-28T13:52:43Z						biological_process											owl:Class	
GO:0019314	biolink:NamedThing	D-allose metabolic process	The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.	got7fsn_ti	D-allose metabolism													biological_process											owl:Class	
GO:1901761	biolink:NamedThing	oxytetracycline metabolic process	The chemical reactions and pathways involving oxytetracycline.	got7fsn_ti	oxytetracycline metabolism						yaf	2013-01-15T09:52:50Z						biological_process											owl:Class	
CHEBI:60980	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071343	biolink:NamedThing	obsolete negative regulation of establishment of actomyosin contractile ring localization	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location.	got7fsn_ti	negative regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis|negative regulation of establishment of actomyosin contractile ring localization|negative regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle|negative regulation of establishment of contractile ring localization involved in cell cycle cytokinesis				This term was made obsolete because it does not describe a wild-type or normal process.		mah	2009-12-11T01:33:14Z		True				biological_process											owl:Class	
GO:0001211	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045718	biolink:NamedThing	obsolete negative regulation of flagellum assembly	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a flagellum.	got7fsn_ti	down regulation of flagellum assembly|negative regulation of flagella assembly|down-regulation of flagellum assembly|negative regulation of flagellum biogenesis|negative regulation of flagellum assembly|downregulation of flagellum assembly|inhibition of flagellum assembly				This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:1902018				True				biological_process											owl:Class	
GO:0051101	biolink:NamedThing	regulation of DNA binding	Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).	got7fsn_ti														biological_process											owl:Class	
CHEBI:47923	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0106193	biolink:NamedThing	obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a diphosphate	OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a diphosphate.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T16:55:24Z		True		EC:7.2.3.-		molecular_function											owl:Class	
GO:0016735	biolink:NamedThing	obsolete vanadium-iron nitrogenase activity	OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.	got7fsn_ti	vanadium-iron nitrogenase activity				This term was made obsolete because it represents a cellular component.	GO:0016613|GO:0016163				True				molecular_function											owl:Class	
GO:0051335	biolink:NamedThing	meiosis II nuclear membrane reassembly	The reformation of the nuclear membrane during meiosis II.	got7fsn_ti	meiosis II nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636												biological_process											owl:Class	
GO:0010081	biolink:NamedThing	regulation of inflorescence meristem growth	Any process involved in maintaining the size and shape of an inflorescence meristem.	got7fsn_ti	regulation of inflorescence meristem size													biological_process											owl:Class	
GO:0051121	biolink:NamedThing	hepoxilin metabolic process	The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.	got7fsn_ti	hepoxilin metabolism													biological_process											owl:Class	
GO:0051900	biolink:NamedThing	regulation of mitochondrial depolarization	Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.	got7fsn_ti														biological_process											owl:Class	
GO:1902835	biolink:NamedThing	negative regulation of proline import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell.	got7fsn_ti	down-regulation of proline import into cell|down regulation of proline import into cell|inhibition of proline import into cell|downregulation of proline import into cell|negative regulation of proline import into cell						mah	2014-04-01T13:44:06Z						biological_process											owl:Class	
GO:2000015	biolink:NamedThing	regulation of determination of dorsal identity	Any process that modulates the frequency, rate or extent of determination of dorsal identity.	got7fsn_ti	regulation of determination of adaxial identity						jl	2010-07-15T03:27:49Z						biological_process											owl:Class	
GO:0019844	biolink:NamedThing	obsolete endotoxin activity	OBSOLETE. The function of any microbial toxin that cannot be easily separated from the structure of the cell.	got7fsn_ti	endotoxin activity				This term was made obsolete because it represents a class of gene products.	GO:0090729|GO:0005622				True				molecular_function											owl:Class	
GO:0001688	biolink:NamedThing	obsolete cytoplasmic dynein intermediate chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytoplasmic dynein intermediate chain			GO:0005868	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:0004244	biolink:NamedThing	obsolete mitochondrial inner membrane peptidase activity	OBSOLETE. Catalysis of the maturation of mitochondrial precursor proteins delivered to the intermembrane space.	got7fsn_ti	mitochondrial inner membrane peptidase activity|IMP			GO:0004175	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0030531	biolink:NamedThing	obsolete small cytoplasmic ribonucleoprotein complex	OBSOLETE. A complex composed of RNA of the small cytoplasmic RNA (scRNA) class and protein, found in the cytoplasm.	got7fsn_ti	small cytoplasmic ribonucleoprotein|scRNP|small cytoplasmic ribonucleoprotein complex			GO:1990904	This term was made obsolete because it was not clearly defined.					True				cellular_component											owl:Class	
GO:1905915	biolink:NamedThing	regulation of cell differentiation involved in phenotypic switching	Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching.	got7fsn_ti							rph	2017-02-08T12:23:14Z						biological_process											owl:Class	
GO:0051805	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901268	biolink:NamedThing	cephalosporin C biosynthetic process	The chemical reactions and pathways resulting in the formation of cephalosporin C.	got7fsn_ti	cephalosporin C biosynthesis|cephalosporin C synthesis|cephalosporin C anabolism|cephalosporin C formation						yaf	2012-08-17T14:26:31Z						biological_process											owl:Class	
UBERON:0004155	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070950	biolink:NamedThing	regulation of neutrophil mediated killing of bacterium	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.	got7fsn_ti							mah	2009-10-01T02:14:36Z						biological_process											owl:Class	
CHEBI:72750	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006226	biolink:NamedThing	dUMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).	got7fsn_ti	dUMP anabolism|dUMP biosynthesis|dUMP formation|dUMP synthesis													biological_process											owl:Class	
GO:0031616	biolink:NamedThing	spindle pole centrosome	A centrosome from which one pole of a mitotic or meiotic spindle is organized.	got7fsn_ti														cellular_component											owl:Class	
GO:0033663	biolink:NamedThing	obsolete negative regulation by symbiont of host defense-related protein level	OBSOLETE. Any process in which the symbiont reduces of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it is a readout, and annotations should be made to more informative terms.					True				biological_process											owl:Class	
GO:0010600	biolink:NamedThing	regulation of auxin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.	got7fsn_ti														biological_process											owl:Class	
GO:0031396	biolink:NamedThing	regulation of protein ubiquitination	Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.	got7fsn_ti														biological_process											owl:Class	
GO:1905346	biolink:NamedThing	protein localization to cleavage furrow rim	A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim.	got7fsn_ti	protein localisation to cleavage furrow rim|protein localisation in cleavage furrow rim|protein localization in cleavage furrow rim						mah	2016-08-01T13:20:13Z						biological_process											owl:Class	
GO:1901951	biolink:NamedThing	regulation of anterograde dense core granule transport	Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.	got7fsn_ti							pr	2013-02-19T13:36:21Z						biological_process											owl:Class	
GO:1902716	biolink:NamedThing	cell cortex of growing cell tip	Any cell cortex that is part of a growing cell tip.	got7fsn_ti	cell cortex of growing cell end						mah	2014-02-24T15:46:57Z						cellular_component											owl:Class	
GO:1903084	biolink:NamedThing	protein localization to condensed nuclear chromosome	A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome.	got7fsn_ti	protein localization in condensed nuclear chromosome|protein localisation to condensed nuclear chromosome|protein localisation in condensed nuclear chromosome						kmv	2014-05-29T20:33:17Z						biological_process											owl:Class	
GO:1901645	biolink:NamedThing	regulation of synoviocyte proliferation	Any process that modulates the frequency, rate or extent of synoviocyte proliferation.	got7fsn_ti							hjd	2012-11-16T20:16:23Z						biological_process											owl:Class	
GO:0110082	biolink:NamedThing	regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti							kmv	2018-02-01T19:25:06Z						biological_process											owl:Class	
GO:0052231	biolink:NamedThing	obsolete modulation of phagocytosis in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modulation of phagocytosis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18562			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0032085	biolink:NamedThing	regulation of type II site-specific deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity.	got7fsn_ti	type II restriction enzyme regulator|regulation of type II restriction endodeoxyribonuclease activity|type II restriction endodeoxyribonuclease regulator													biological_process											owl:Class	
GO:0030569	biolink:NamedThing	obsolete chymotrypsin inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase chymotrypsin.	got7fsn_ti	chymotrypsin inhibitor activity			GO:0004867	This term was made obsolete because it represents a regulator of an obsolete molecular function term.					True				molecular_function											owl:Class	
GO:0000052	biolink:NamedThing	citrulline metabolic process	The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.	got7fsn_ti	citrulline metabolism													biological_process											owl:Class	
GO:0006736	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090311	biolink:NamedThing	regulation of protein deacetylation	Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	got7fsn_ti	regulation of protein amino acid deacetylation						tb	2010-04-14T01:30:45Z						biological_process											owl:Class	
GO:1904103	biolink:NamedThing	regulation of convergent extension involved in gastrulation	Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation.	got7fsn_ti							dph	2015-04-01T11:17:05Z						biological_process											owl:Class	
GO:1900225	biolink:NamedThing	regulation of NLRP3 inflammasome complex assembly	Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly.	got7fsn_ti	regulation of NALP3 inflammasome complex assembly|regulation of NLRP3 inflammasome activation						jl	2012-03-22T04:18:14Z						biological_process											owl:Class	
GO:1903618	biolink:NamedThing	regulation of transdifferentiation	Any process that modulates the frequency, rate or extent of transdifferentiation.	got7fsn_ti							jl	2014-11-19T11:24:57Z						biological_process											owl:Class	
GO:1904690	biolink:NamedThing	positive regulation of cytoplasmic translational initiation	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.	got7fsn_ti	activation of cytoplasmic translational initiation|up regulation of cytoplasmic translational initiation|up-regulation of cytoplasmic translational initiation|upregulation of cytoplasmic translational initiation						dos	2015-09-25T14:39:50Z						biological_process											owl:Class	
CL:0002630	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000735	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905562	biolink:NamedThing	regulation of vascular endothelial cell proliferation	Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation.	got7fsn_ti							nc	2016-10-17T09:24:17Z						biological_process											owl:Class	
GO:0009169	biolink:NamedThing	purine ribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine ribonucleoside monophosphate catabolism|purine ribonucleoside monophosphate breakdown|purine ribonucleoside monophosphate degradation													biological_process											owl:Class	
UBERON:2000120	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071235	biolink:NamedThing	cellular response to proline	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.	got7fsn_ti							mah	2009-12-03T02:09:45Z						biological_process											owl:Class	
GO:0002860	biolink:NamedThing	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.	got7fsn_ti	up-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|upregulation of natural killer cell mediated cytotoxicity directed against tumor cell target|stimulation of natural killer cell mediated cytotoxicity directed against tumor cell target|activation of natural killer cell mediated cytotoxicity directed against tumor cell target|up regulation of natural killer cell mediated cytotoxicity directed against tumor cell target													biological_process											owl:Class	
GO:0048127	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090222	biolink:NamedThing	centrosome-templated microtubule nucleation	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.	got7fsn_ti							tb	2010-01-13T10:52:36Z						biological_process											owl:Class	
GO:0007559	biolink:NamedThing	obsolete histolysis	OBSOLETE. The breakdown of tissues; usually, if not always, accompanied by cell death, followed by the complete dissolution of dead tissue.	got7fsn_ti					This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0008219|GO:0012501				True		Wikipedia:Histolysis		biological_process											owl:Class	
GO:1903567	biolink:NamedThing	regulation of protein localization to ciliary membrane	Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane.	got7fsn_ti	regulation of protein localisation in ciliary membrane|regulation of protein localisation to ciliary membrane|regulation of protein localization in ciliary membrane						krc	2014-10-24T21:32:51Z						biological_process											owl:Class	
GO:2001213	biolink:NamedThing	negative regulation of vasculogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis.	got7fsn_ti	negative regulation of vascular morphogenesis						yaf	2011-11-15T01:22:36Z						biological_process											owl:Class	
GO:0042308	biolink:NamedThing	negative regulation of protein import into nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.	got7fsn_ti	down-regulation of protein import into nucleus|negative regulation of protein transport from cytoplasm to nucleus|downregulation of protein import into nucleus|down regulation of protein import into nucleus|negative regulation of protein-nucleus import|inhibition of protein import into nucleus|negative regulation of protein import into cell nucleus													biological_process											owl:Class	
GO:0061096	biolink:NamedThing	negative regulation of turning behavior involved in mating	Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.	got7fsn_ti							dph	2010-04-26T02:12:24Z						biological_process											owl:Class	
CHEBI:64283	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000092	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903697	biolink:NamedThing	negative regulation of microvillus assembly	Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly.	got7fsn_ti	downregulation of microvillus biogenesis|down-regulation of microvillus assembly|inhibition of microvillus biogenesis|down-regulation of microvillus biogenesis|negative regulation of microvillus biogenesis|inhibition of microvillus assembly|down regulation of microvillus assembly|downregulation of microvillus assembly|down regulation of microvillus biogenesis						als	2014-12-03T11:45:08Z						biological_process											owl:Class	
GO:0061851	biolink:NamedThing	leading edge of lamellipodium	That part of the lamellipodium which represents the distal part of the structure.	got7fsn_ti														cellular_component											owl:Class	
GO:1901139	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001684	biolink:NamedThing	obsolete axonemal dynein intermediate chain	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	axonemal dynein intermediate chain			GO:0005858	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
UBERON:0001765	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001660	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072279	biolink:NamedThing	convergent extension involved in metanephric nephron morphogenesis	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros.	got7fsn_ti							mah	2010-04-01T03:16:11Z						biological_process											owl:Class	
GO:1901509	biolink:NamedThing	regulation of endothelial tube morphogenesis	Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis.	got7fsn_ti							dph	2012-10-17T14:30:40Z						biological_process											owl:Class	
GO:0032977	biolink:NamedThing	membrane insertase activity	Binds transmembrane domain-containing proteins and mediates their integration into a membrane.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16976|https://github.com/geneontology/go-ontology/issues/20414										Reactome:R-HSA-1268025|Reactome:R-HSA-1307803|Reactome:R-HSA-1299482		molecular_function											owl:Class	
GO:0002057	biolink:NamedThing	guanine binding	Binding to guanine.	got7fsn_ti														molecular_function											owl:Class	
GO:0017106	biolink:NamedThing	obsolete activin inhibitor activity	OBSOLETE. Acts to negatively regulate the activity of activin, a nonsteroidal regulator synthesized in the pituitary gland and gonads that stimulates the secretion of follicle-stimulating hormone.	got7fsn_ti	activin inhibitor activity				This term was made obsolete because it refers to an obsolete molecular function term, 'activin'.	GO:0098772				True				molecular_function											owl:Class	
GO:0008046	biolink:NamedThing	axon guidance receptor activity	Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.	got7fsn_ti	receptor activity involved in axon guidance													molecular_function											owl:Class	
GO:1905947	biolink:NamedThing	positive regulation of response to calcium ion	Any process that activates or increases the frequency, rate or extent of response to calcium ion.	got7fsn_ti	up regulation of response to Ca2+ ion|up-regulation of response to Ca2+ ion|up regulation of response to calcium ion|activation of response to calcium ion|up-regulation of response to calcium ion|positive regulation of response to Ca2+ ion|upregulation of response to Ca2+ ion|upregulation of response to calcium ion|activation of response to Ca2+ ion						bc	2017-02-13T10:56:49Z						biological_process											owl:Class	
GO:0099166	biolink:NamedThing	intrinsic component of postsynaptic specialization membrane of symmetric synapse	The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to postsynaptic specialization membrane of symmetric synapse						dos	2017-09-10T11:56:47Z						cellular_component											owl:Class	
GO:0098990	biolink:NamedThing	AMPA selective glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti														biological_process											owl:Class	
GO:0052195	biolink:NamedThing	obsolete movement on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of an organism or motile cell on or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	movement on or near other organism during symbiotic interaction				This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
CHEBI:57651	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000393	biolink:NamedThing	negative regulation of lamellipodium morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis.	got7fsn_ti	negative regulation of lamellipodium organization						mah	2011-02-22T11:19:25Z						biological_process											owl:Class	
GO:0140409	biolink:NamedThing	positive regulation of mRNA alternative polyadenylation	Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15389					pg	2019-12-13T12:48:31Z						biological_process											owl:Class	
GO:0043298	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PO:0025267	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002005	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048632	biolink:NamedThing	negative regulation of skeletal muscle tissue growth	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.	got7fsn_ti	downregulation of skeletal muscle growth|down-regulation of skeletal muscle growth|down regulation of skeletal muscle growth|inhibition of skeletal muscle growth													biological_process											owl:Class	
CHEBI:48958	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27353	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032355	biolink:NamedThing	response to estradiol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	got7fsn_ti	response to E2 stimulus|response to estradiol stimulus													biological_process											owl:Class	
GO:1901961	biolink:NamedThing	isobutanol biosynthetic process	The chemical reactions and pathways resulting in the formation of isobutanol.	got7fsn_ti	isobutanol synthesis|isobutanol biosynthesis|isobutanol formation|isobutanol anabolism						tt	2013-02-19T21:49:49Z						biological_process											owl:Class	
GO:1905568	biolink:NamedThing	regulation of ferrichrome biosynthetic process	Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process.	got7fsn_ti	regulation of ferrichrome biosynthesis|regulation of ferrichrome anabolism|regulation of ferrichrome synthesis|regulation of ferrichrome biosynthetic process, peptide modification|regulation of ferrichrome formation|regulation of ferrichrome biosynthetic process, peptide formation						pr	2016-10-18T14:49:00Z						biological_process											owl:Class	
GO:0150179	biolink:NamedThing	positive regulation of phosphatidylserine metabolic process	Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process.	got7fsn_ti							bc	2020-01-21T14:05:52Z						biological_process											owl:Class	
GO:1901934	biolink:NamedThing	bicyclogermacrene biosynthetic process	The chemical reactions and pathways resulting in the formation of bicyclogermacrene.	got7fsn_ti	bicyclogermacrene anabolism|bicyclogermacrene biosynthesis|bicyclogermacrene synthesis|bicyclogermacrene formation						ms	2013-02-18T14:55:01Z						biological_process											owl:Class	
GO:0002722	biolink:NamedThing	negative regulation of B cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.	got7fsn_ti	negative regulation of B-cell cytokine production|negative regulation of B lymphocyte cytokine production|inhibition of B cell cytokine production|down regulation of B cell cytokine production|downregulation of B cell cytokine production|down-regulation of B cell cytokine production|negative regulation of B-lymphocyte cytokine production													biological_process											owl:Class	
GO:0046305	biolink:NamedThing	alkanesulfonate biosynthetic process	The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.	got7fsn_ti	alkanesulfonate formation|alkanesulfonate anabolism|alkanesulfonate synthesis|alkanesulphonate biosynthetic process|alkanesulfonate biosynthesis|alkanesulphonate biosynthesis													biological_process											owl:Class	
GO:1901007	biolink:NamedThing	(S)-scoulerine metabolic process	The chemical reactions and pathways involving (S)-scoulerine.	got7fsn_ti	(S)-scoulerine metabolism						yaf	2012-06-15T10:45:48Z						biological_process											owl:Class	
GO:0099030	biolink:NamedThing	anchored component of postsynaptic specialization membrane	The component of the postsynaptic specialization membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0010612	biolink:NamedThing	regulation of cardiac muscle adaptation	Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.	got7fsn_ti														biological_process											owl:Class	
GO:1905550	biolink:NamedThing	regulation of protein localization to endoplasmic reticulum	Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum.	got7fsn_ti	regulation of protein localization in ER|regulation of protein localisation in endoplasmic reticulum|regulation of protein localization in endoplasmic reticulum						rz	2016-10-12T11:37:01Z						biological_process											owl:Class	
GO:0071556	biolink:NamedThing	integral component of lumenal side of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.	got7fsn_ti	integral to lumenal side of endoplasmic reticulum membrane|integral to ER membrane, lumenal side|integral to lumenal side of ER membrane|integral to lumenal leaflet of endoplasmic reticulum membrane						mah	2010-01-15T10:56:58Z						cellular_component											owl:Class	
GO:0042499	biolink:NamedThing	obsolete signal peptide peptidase activity	OBSOLETE. Catalysis of the intramembrane proteolysis of a signal peptide, following its removal from a preprotein.	got7fsn_ti	SPP|signal peptide peptidase activity			GO:0042500	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0003773	biolink:NamedThing	obsolete heat shock protein activity	OBSOLETE. Any of a group of specific proteins that are synthesized by both prokaryotic and eukaryotic cells after they have been exposed to a temperature that is higher than normal. Other stresses, e.g. free radical damage, have a similar effect. Many members of the hsp family are not induced but are present in all cells. They are characterized by their role as molecular chaperones.	got7fsn_ti	heat shock protein activity				This term was made obsolete because it represents a class of gene products rather than a molecular function.	GO:0006986|GO:0042026				True				molecular_function											owl:Class	
CHEBI:59326	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002920	biolink:NamedThing	regulation of humoral immune response	Any process that modulates the frequency, rate, or extent of a humoral immune response.	got7fsn_ti														biological_process											owl:Class	
GO:0075286	biolink:NamedThing	regulation of sporangiospore formation	Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.	got7fsn_ti														biological_process											owl:Class	
GO:0006857	biolink:NamedThing	oligopeptide transport	The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	got7fsn_ti														biological_process											owl:Class	
GO:0045866	biolink:NamedThing	obsolete positive regulation of recombination within rDNA repeats	OBSOLETE. Any process that activates or increases the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.	got7fsn_ti	positive regulation of recombination within rDNA repeats				This term was made obsolete because it describes a substrate-specific process.	GO:0045951				True				biological_process											owl:Class	
GO:2000038	biolink:NamedThing	regulation of stomatal complex development	Any process that modulates the frequency, rate or extent of stomatal complex development.	got7fsn_ti							tb	2010-08-05T11:36:10Z						biological_process											owl:Class	
GO:0032765	biolink:NamedThing	positive regulation of mast cell cytokine production	Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production.	got7fsn_ti	upregulation of mast cell cytokine production|up regulation of mast cell cytokine production|up-regulation of mast cell cytokine production|activation of mast cell cytokine production|stimulation of mast cell cytokine production													biological_process											owl:Class	
CHEBI:37586	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002619	biolink:NamedThing	regulation of non-professional antigen presenting cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:1903083	biolink:NamedThing	protein localization to condensed chromosome	A process in which a protein is transported to, or maintained in, a location within a condensed chromosome.	got7fsn_ti	protein localisation to condensed chromosome|protein localization in condensed chromosome|protein localisation in condensed chromosome						kmv	2014-05-29T20:31:25Z						biological_process											owl:Class	
CHEBI:26191	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902581	biolink:NamedThing	multi-organism cellular localization	A cellular localization which involves another organism.	got7fsn_ti	multi organism cellular localization						jl	2013-12-18T14:04:41Z						biological_process											owl:Class	
GO:0051488	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034312	biolink:NamedThing	diol biosynthetic process	The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.	got7fsn_ti	diol anabolism|diol biosynthesis|diol formation|dihydric alcohol biosynthetic process|diol synthesis													biological_process											owl:Class	
GO:0071648	biolink:NamedThing	positive regulation of macrophage inflammatory protein-1 gamma production	Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.	got7fsn_ti	positive regulation of CCL9 production|positive regulation of MIP-1g production|positive regulation of chemokine (C-C motif) ligand 9 production						mah	2010-02-12T10:40:19Z						biological_process											owl:Class	
GO:0007148	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042848	biolink:NamedThing	sorbose catabolic process	The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.	got7fsn_ti	sorbose degradation|sorbose catabolism|sorbose breakdown													biological_process											owl:Class	
GO:1900692	biolink:NamedThing	regulation of (+)-kotanin biosynthetic process	Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process.	got7fsn_ti	regulation of (+)-kotanin anabolism|regulation of (+)-kotanin biosynthesis|regulation of (+)-kotanin synthesis|regulation of (+)-kotanin formation						di	2012-05-22T04:53:04Z						biological_process											owl:Class	
GO:0032316	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903715	biolink:NamedThing	regulation of aerobic respiration	Any process that modulates the frequency, rate or extent of aerobic respiration.	got7fsn_ti							al	2014-12-08T00:40:37Z						biological_process											owl:Class	
GO:1905933	biolink:NamedThing	regulation of cell fate determination	Any process that modulates the frequency, rate or extent of cell fate determination.	got7fsn_ti							bhm	2017-02-09T11:25:21Z						biological_process											owl:Class	
GO:1903331	biolink:NamedThing	positive regulation of iron-sulfur cluster assembly	Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly.	got7fsn_ti	up regulation of iron-sulphur cluster assembly|upregulation of iron-sulfur cluster biosynthesis|positive regulation of iron-sulphur cluster assembly|up regulation of iron-sulfur cluster assembly|activation of iron-sulfur cluster assembly|activation of iron-sulphur cluster assembly|upregulation of iron-sulphur cluster assembly|positive regulation of iron-sulfur cluster biosynthesis|up-regulation of iron-sulfur cluster assembly|upregulation of iron-sulfur cluster assembly|up-regulation of iron-sulfur cluster biosynthesis|activation of iron-sulfur cluster biosynthesis|up regulation of iron-sulfur cluster biosynthesis|up-regulation of iron-sulphur cluster assembly						vw	2014-08-18T13:12:57Z						biological_process											owl:Class	
GO:0048375	biolink:NamedThing	negative regulation of lateral mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination.	got7fsn_ti	inhibition of lateral mesodermal cell fate determination|down regulation of lateral mesodermal cell fate determination|down-regulation of lateral mesodermal cell fate determination|downregulation of lateral mesodermal cell fate determination|negative regulation of lateral plate mesodermal cell fate determination													biological_process											owl:Class	
CL:0002453	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000305	biolink:NamedThing	semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance	Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance.	got7fsn_ti	semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon pathfinding|semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon guidance|semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon guidance|semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon pathfinding						sart	2011-01-07T01:42:34Z						biological_process											owl:Class	
GO:0035274	biolink:NamedThing	diphenyl phthalate binding	Binding to diphenyl phthalate, C(20)H(14)O(4).	got7fsn_ti	DPP binding													molecular_function											owl:Class	
GO:0010662	biolink:NamedThing	regulation of striated muscle cell apoptotic process	Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.	got7fsn_ti	regulation of striated muscle cell apoptosis													biological_process											owl:Class	
GO:0015348	biolink:NamedThing	obsolete prostaglandin/thromboxane transporter activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	prostaglandin/thromboxane transporter activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0008028|GO:0015132				True				molecular_function											owl:Class	
GO:2000331	biolink:NamedThing	regulation of terminal button organization	Any process that modulates the frequency, rate or extent of terminal button organization.	got7fsn_ti	regulation of presynaptic bouton organization|regulation of terminal button organisation|regulation of bouton organization|regulation of synaptic bouton organization|regulation of terminal bouton organization						mah	2011-01-28T11:29:08Z						biological_process											owl:Class	
GO:0046624	biolink:NamedThing	sphingolipid transporter activity	Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	got7fsn_ti												Reactome:R-HSA-9695890		molecular_function											owl:Class	
GO:0003303	biolink:NamedThing	BMP signaling pathway involved in heart jogging	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the process of heart jogging.	got7fsn_ti	BMP signalling pathway involved in heart jogging						dph	2009-10-22T11:00:58Z						biological_process											owl:Class	
GO:0070798	biolink:NamedThing	positive regulation of cleistothecium development	Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	got7fsn_ti							mah	2009-07-08T03:36:43Z						biological_process											owl:Class	
GO:0045219	biolink:NamedThing	regulation of FasL production	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.	got7fsn_ti	regulation of FasL anabolism|regulation of FasL formation|regulation of FasL biosynthesis|regulation of FasL synthesis													biological_process											owl:Class	
GO:0052066	biolink:NamedThing	obsolete entry of symbiont into host cell by promotion of host phagocytosis	OBSOLETE. The invasion by a symbiont of a host organism cell by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	penetration of organism into host cell by promotion of host phagocytosis|entry of organism into host cell by promotion of host phagocytosis|entry of organism into cell of other organism by promotion of phagocytosis in other organism during symbiotic interaction|penetration of symbiont into host cell by promotion of host phagocytosis|entry of organism into cell of other organism by promotion of phagocytosis in other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18562			This term was obsoleted because it was misused.					True				biological_process											owl:Class	
GO:0005571	biolink:NamedThing	obsolete untranslated RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	untranslated RNA				Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True				cellular_component											owl:Class	
GO:0052228	biolink:NamedThing	obsolete metabolism by symbiont of host protein	OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
UBERON:0004292	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051199	biolink:NamedThing	regulation of prosthetic group metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.	got7fsn_ti	regulation of coenzyme and prosthetic group metabolism|regulation of prosthetic group metabolism|regulation of coenzyme and prosthetic group metabolic process													biological_process											owl:Class	
GO:0099110	biolink:NamedThing	microtubule polymerization based protein transport to cell tip cortex	The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached.	got7fsn_ti														biological_process											owl:Class	
GO:0009464	biolink:NamedThing	obsolete cytochrome b5	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	cytochrome b5				This term was made obsolete because it represents a gene product.	GO:0009055				True				molecular_function											owl:Class	
GO:0045661	biolink:NamedThing	regulation of myoblast differentiation	Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	got7fsn_ti														biological_process											owl:Class	
GO:0150141	biolink:NamedThing	negative regulation of CD86 production	Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process.	got7fsn_ti	negative regulation of CD86 biosynthetic process						bc	2019-12-08T09:33:39Z						biological_process											owl:Class	
GO:0005246	biolink:NamedThing	calcium channel regulator activity	Modulates the activity of a calcium channel.	got7fsn_ti														molecular_function											owl:Class	
GO:1900479	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043390	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002060	biolink:NamedThing	purine nucleobase binding	Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.	got7fsn_ti	purine base binding|purine binding													molecular_function											owl:Class	
GO:0031542	biolink:NamedThing	positive regulation of anthocyanin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.	got7fsn_ti	stimulation of anthocyanin biosynthetic process|up-regulation of anthocyanin biosynthetic process|upregulation of anthocyanin biosynthetic process|positive regulation of anthocyanin synthesis|positive regulation of anthocyanin formation|positive regulation of anthocyanin biosynthesis|activation of anthocyanin biosynthetic process|positive regulation of anthocyanin anabolism|up regulation of anthocyanin biosynthetic process													biological_process											owl:Class	
CL:1000428	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033048	biolink:NamedThing	negative regulation of mitotic sister chromatid segregation	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.	got7fsn_ti														biological_process											owl:Class	
GO:0005241	biolink:NamedThing	obsolete inward rectifier channel	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	inward rectifier channel				This term was made obsolete because more specific terms were created.	GO:0005242				True				molecular_function											owl:Class	
GO:0032908	biolink:NamedThing	regulation of transforming growth factor beta1 production	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1.	got7fsn_ti	regulation of TGFB1 production|regulation of TGF-B1 production|regulation of transforming growth factor-beta1 production													biological_process											owl:Class	
GO:0033233	biolink:NamedThing	regulation of protein sumoylation	Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.	got7fsn_ti	regulation of sumoylation													biological_process											owl:Class	
GO:0019877	biolink:NamedThing	diaminopimelate biosynthetic process	The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.	got7fsn_ti	diaminopimelate biosynthesis|diaminopimelate formation|diaminopimelate anabolism|diaminopimelate synthesis													biological_process											owl:Class	
GO:1903981	biolink:NamedThing	enterobactin binding	Binding to enterobactin.	got7fsn_ti	enterochelin binding|siderophore binding						mr	2015-03-02T17:21:54Z						molecular_function											owl:Class	
GO:0052643	biolink:NamedThing	chlorophyllide metabolic process	The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl.	got7fsn_ti	chlorophyllide metabolism													biological_process											owl:Class	
UBERON:0001638	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902585	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019692	biolink:NamedThing	deoxyribose phosphate metabolic process	The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.	got7fsn_ti	deoxyribose phosphate metabolism													biological_process											owl:Class	
GO:1905187	biolink:NamedThing	negative regulation of metaphase/anaphase transition of meiosis I	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I.	got7fsn_ti							vw	2016-05-10T16:32:11Z						biological_process											owl:Class	
GO:1901797	biolink:NamedThing	negative regulation of signal transduction by p53 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator.	got7fsn_ti	inhibition of signal transduction by p53 class mediator|downregulation of signal transduction by p53 class mediator|down-regulation of signal transduction by p53 class mediator|down regulation of signal transduction by p53 class mediator						hjd	2013-01-18T21:51:44Z						biological_process											owl:Class	
GO:0015965	biolink:NamedThing	diadenosine tetraphosphate metabolic process	The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.	got7fsn_ti	diadenosine tetraphosphate metabolism													biological_process											owl:Class	
GO:0072439	biolink:NamedThing	obsolete detection of stimulus involved in meiotic DNA replication checkpoint	OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a meiotic DNA replication checkpoint.	got7fsn_ti	meiotic DNA replication checkpoint sensor process|meiotic DNA replication checkpoint sensor mechanism|sensing involved in meiotic DNA replication checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:59:08Z		True				biological_process											owl:Class	
GO:2000894	biolink:NamedThing	cellotriose catabolic process	The chemical reactions and pathways resulting in the breakdown of a cellotriose.	got7fsn_ti	cellotriose catabolism						jl	2011-07-28T02:02:47Z						biological_process											owl:Class	
GO:2001298	biolink:NamedThing	N(omega),N(omega)-dimethyl-L-arginine metabolic process	The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.	got7fsn_ti	N(omega),N(omega)-dimethyl-L-arginine metabolism						pr	2012-02-14T03:39:59Z						biological_process											owl:Class	
CHEBI:76842	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019759	biolink:NamedThing	glycosinolate catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.	got7fsn_ti	glycosinolate degradation|glycosinolate catabolism|glycosinolate breakdown													biological_process											owl:Class	
GO:0016083	biolink:NamedThing	obsolete synaptic vesicle fusion	OBSOLETE. Fusion of the synaptic vesicle with the postsynaptic membrane.	got7fsn_ti	synaptic vesicle fusion				This term was made obsolete because it was wrongly defined.	GO:0016192				True				biological_process											owl:Class	
GO:1901538	biolink:NamedThing	changes to DNA methylation involved in embryo development	The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression.	got7fsn_ti	DNA methylation or demethylation involved in embryonal development|changes in DNA methylation involved in embryonal development|DNA methylation or demethylation involved in embryogenesis|changes in DNA methylation involved in embryogenesis|changes in DNA methylation involved in embryo development						jl	2012-10-25T14:53:43Z						biological_process											owl:Class	
GO:0035481	biolink:NamedThing	positive regulation of Notch signaling pathway involved in heart induction	Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.	got7fsn_ti	positive regulation of Notch signalling pathway involved in heart induction						bf	2010-04-23T10:41:04Z						biological_process											owl:Class	
CHEBI:26437	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001100	biolink:NamedThing	pentasaccharide transport	The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:17:07Z						biological_process											owl:Class	
GO:0033632	biolink:NamedThing	regulation of cell-cell adhesion mediated by integrin	Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.	got7fsn_ti	regulation of cell-cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:2000967	biolink:NamedThing	negative regulation of cell wall polysaccharide catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process.	got7fsn_ti	negative regulation of cell wall polysaccharide breakdown						tt	2011-08-01T02:30:33Z						biological_process											owl:Class	
CHEBI:77857	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990554	biolink:NamedThing	mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport	The process in which 3'-phospho-5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.	got7fsn_ti							vw	2014-11-19T12:39:22Z						biological_process											owl:Class	
GO:0035063	biolink:NamedThing	nuclear speck organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.	got7fsn_ti	nuclear speckle assembly|nuclear speck organization and biogenesis|nuclear speckle organization|nuclear speck organisation				See also the cellular component term 'nuclear speck ; GO:0016607'.									biological_process											owl:Class	
GO:0008201	biolink:NamedThing	heparin binding	Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.	got7fsn_ti	heparan sulfate binding													molecular_function											owl:Class	
GO:0061462	biolink:NamedThing	protein localization to lysosome	A process in which a protein is transported to, or maintained in, a location within a lysosome.	got7fsn_ti							dph	2012-10-05T10:50:51Z						biological_process											owl:Class	
GO:0060990	biolink:NamedThing	lipid tube assembly involved in organelle fission	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission.	got7fsn_ti	lipid tubulation involved in organelle fission						dph	2010-01-11T02:14:48Z						biological_process											owl:Class	
GO:0031438	biolink:NamedThing	negative regulation of mRNA cleavage	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage.	got7fsn_ti	downregulation of mRNA cleavage|down regulation of mRNA cleavage|down-regulation of mRNA cleavage|inhibition of mRNA cleavage													biological_process											owl:Class	
GO:1904627	biolink:NamedThing	response to phorbol 13-acetate 12-myristate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.	got7fsn_ti	response to phorbol 12-tetradecanoate 13-acetate|response to tetradecanoylphorbol acetate|response to TPA|response to PMA						sl	2015-08-28T13:44:03Z						biological_process											owl:Class	
GO:0071879	biolink:NamedThing	positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.	got7fsn_ti	positive regulation of adrenergic receptor signaling pathway|positive regulation of adrenergic receptor signalling pathway						mah	2010-09-13T04:15:57Z						biological_process											owl:Class	
CHEBI:15963	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900306	biolink:NamedThing	regulation of maltoheptaose transport	Any process that modulates the frequency, rate or extent of maltoheptaose transport.	got7fsn_ti							tt	2012-04-05T07:58:18Z						biological_process											owl:Class	
GO:0035058	biolink:NamedThing			got7fsn_ti										True															owl:Class	
SO:0000370	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:4000163	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902084	biolink:NamedThing	fumagillin metabolic process	The chemical reactions and pathways involving fumagillin.	got7fsn_ti	fumagillin metabolism						di	2013-04-25T14:00:41Z						biological_process											owl:Class	
GO:1904390	biolink:NamedThing	cone retinal bipolar cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell.	got7fsn_ti	retinal cone bipolar cell differentiation|cone bipolar cell differentiation						sl	2015-06-23T19:01:16Z						biological_process											owl:Class	
GO:1902592	biolink:NamedThing	obsolete multi-organism membrane budding	OBSOLETE. A membrane budding which involves another organism.	got7fsn_ti	multi organism membrane budding				Obsoleted because it was a grouping term for a viral process that was incorrectly under 'multi-organism cellular process'. The children terms have been moved under 'viral process', so that this grouping term is not necessary anymore.		jl	2013-12-19T15:26:25Z		True				biological_process											owl:Class	
OBO:OBA_0000088	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002078	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62785	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3392	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:20056	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5385	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010379	biolink:NamedThing	phaseic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA).	got7fsn_ti												MetaCyc:PWY-5271		biological_process											owl:Class	
GO:0035719	biolink:NamedThing	tRNA import into nucleus	The directed movement of tRNA from the cytoplasm to the nucleus.	got7fsn_ti	retrograde tRNA transport into nucleus|tRNA nuclear import						bf	2011-03-03T04:32:35Z						biological_process											owl:Class	
CHEBI:62756	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010753	biolink:NamedThing	positive regulation of cGMP-mediated signaling	Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.	got7fsn_ti	positive regulation of cGMP-mediated signalling													biological_process											owl:Class	
GO:0030416	biolink:NamedThing	methylamine metabolic process	The chemical reactions and pathways involving methylamine (CH3NH2).	got7fsn_ti	methylammonium metabolic process|methylammonium metabolism|methylamine metabolism													biological_process											owl:Class	
GO:0006230	biolink:NamedThing	TMP biosynthetic process	The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.	got7fsn_ti	TMP formation|TMP synthesis|TMP biosynthesis|TMP anabolism													biological_process											owl:Class	
GO:1905465	biolink:NamedThing	regulation of G-quadruplex DNA unwinding	Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding.	got7fsn_ti							ans	2016-09-19T12:15:45Z						biological_process											owl:Class	
GO:1905583	biolink:NamedThing	cellular response to mannose	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.	got7fsn_ti							pga	2016-10-21T11:40:47Z						biological_process											owl:Class	
PR:000001240	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042969	biolink:NamedThing	obsolete lactone transport	OBSOLETE. The directed movement of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	got7fsn_ti					This term aws obsoleted because there is no evidence for a specific pathway to transport lactone.					True				biological_process											owl:Class	
GO:0010727	biolink:NamedThing	negative regulation of hydrogen peroxide metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.	got7fsn_ti	negative regulation of hydrogen peroxide metabolism													biological_process											owl:Class	
CL:0001035	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000479	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046433	biolink:NamedThing	2-aminoethylphosphonate metabolic process	The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms.	got7fsn_ti	ciliatine metabolism|2-phosphonoethylamine metabolic process|ciliatine metabolic process|2-aminoethylphosphonate metabolism|2-phosphonoethylamine metabolism													biological_process											owl:Class	
GO:1903879	biolink:NamedThing	11beta-hydroxyprogesterone binding	Binding to 11beta-hydroxyprogesterone.	got7fsn_ti							mr	2015-02-06T16:03:12Z						molecular_function											owl:Class	
GO:1904944	biolink:NamedThing	positive regulation of cardiac ventricle formation	Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation.	got7fsn_ti	upregulation of cardiac ventricle formation|up regulation of cardiac ventricle formation|activation of cardiac ventricle formation|up-regulation of cardiac ventricle formation						bc	2016-02-02T16:37:31Z						biological_process											owl:Class	
GO:1901817	biolink:NamedThing	beta-zeacarotene catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene.	got7fsn_ti	beta-zeacarotene breakdown|beta-zeacarotene catabolism|beta-zeacarotene degradation						yaf	2013-01-22T10:42:08Z						biological_process											owl:Class	
GO:1990087	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060915	biolink:NamedThing	mesenchymal cell differentiation involved in lung development	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.	got7fsn_ti							dph	2009-09-18T11:45:33Z						biological_process											owl:Class	
CHEBI:16716	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000002122	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905595	biolink:NamedThing	regulation of low-density lipoprotein particle receptor binding	Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding.	got7fsn_ti	regulation of LDL receptor binding|regulation of low-density lipoprotein receptor binding						nc	2016-10-26T10:57:23Z						biological_process											owl:Class	
GO:0034372	biolink:NamedThing	very-low-density lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.	got7fsn_ti	intermediate-density lipoprotein particle formation|VLDL remodeling|IDL formation													biological_process											owl:Class	
UBERON:0005076	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043151	biolink:NamedThing	DNA synthesis involved in double-strand break repair via single-strand annealing	The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing.	got7fsn_ti	DNA synthesis during double-strand break repair via single-strand annealing													biological_process											owl:Class	
GO:0120172	biolink:NamedThing	positive regulation of actin filament bundle convergence involved in mitotic contractile ring assembly	Any process that activates or increases the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly.	got7fsn_ti							krc	2018-05-31T17:54:35Z						biological_process											owl:Class	
GO:1905127	biolink:NamedThing	negative regulation of axo-dendritic protein transport	Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport.	got7fsn_ti	inhibition of axonal protein transport|downregulation of axonal protein transport|downregulation of axo-dendritic protein transport|inhibition of axo-dendritic protein transport|down-regulation of axo-dendritic protein transport|down-regulation of axonal protein transport|down regulation of axonal protein transport|negative regulation of axonal protein transport|down regulation of axo-dendritic protein transport						sl	2016-04-11T20:38:40Z						biological_process											owl:Class	
GO:0034764	biolink:NamedThing	positive regulation of transmembrane transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.	got7fsn_ti	up regulation of transmembrane transport|stimulation of transmembrane transport|upregulation of transmembrane transport|up-regulation of transmembrane transport|positive regulation of membrane transport|activation of transmembrane transport													biological_process											owl:Class	
CHEBI:26588	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052144	biolink:NamedThing	obsolete negative energy taxis in host	OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative energy taxis within host	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0090239	biolink:NamedThing	regulation of histone H4 acetylation	Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.	got7fsn_ti							tb	2010-01-20T03:48:09Z						biological_process											owl:Class	
CHEBI:74224	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060569	biolink:NamedThing	positive regulation of peptide hormone processing	Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.	got7fsn_ti							dph	2009-04-29T03:22:05Z						biological_process											owl:Class	
CHEBI:29864	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000856	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045588	biolink:NamedThing	positive regulation of gamma-delta T cell differentiation	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.	got7fsn_ti	positive regulation of gamma-delta T-lymphocyte differentiation|positive regulation of gamma-delta T-cell differentiation|up regulation of gamma-delta T cell differentiation|positive regulation of gamma-delta T lymphocyte differentiation|up-regulation of gamma-delta T cell differentiation|upregulation of gamma-delta T cell differentiation|positive regulation of gamma-delta T cell development|stimulation of gamma-delta T cell differentiation|activation of gamma-delta T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:2001127	biolink:NamedThing	methane biosynthetic process from formic acid	The chemical reactions and pathways resulting in the formation of a methane from a formic acid.	got7fsn_ti							jl	2011-10-13T09:54:03Z						biological_process											owl:Class	
GO:0019816	biolink:NamedThing	obsolete B cell receptor accessory molecule complex	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	B cell receptor accessory molecule complex				This term was made obsolete because it represents a molecule and not a location or complex.	GO:0019815				True				cellular_component											owl:Class	
GO:0007327	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904386	biolink:NamedThing	response to L-phenylalanine derivative	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.	got7fsn_ti							sl	2015-06-23T17:56:19Z						biological_process											owl:Class	
CHEBI:64677	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:2000523	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043440	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000417	biolink:NamedThing	negative regulation of eosinophil migration	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration.	got7fsn_ti							mah	2011-02-23T01:43:52Z						biological_process											owl:Class	
GO:0045584	biolink:NamedThing	negative regulation of cytotoxic T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation.	got7fsn_ti	down-regulation of cytotoxic T cell differentiation|negative regulation of cytotoxic T lymphocyte differentiation|downregulation of cytotoxic T cell differentiation|negative regulation of cytotoxic T-cell differentiation|down regulation of cytotoxic T cell differentiation|negative regulation of cytotoxic T cell development|negative regulation of cytotoxic T-lymphocyte differentiation|inhibition of cytotoxic T cell differentiation				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0060620	biolink:NamedThing	regulation of cholesterol import	Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.	got7fsn_ti							dph	2009-05-18T01:41:08Z						biological_process											owl:Class	
GO:0034037	biolink:NamedThing	purine ribonucleoside bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	purine ribonucleoside bisphosphate breakdown|purine ribonucleoside bisphosphate catabolism|purine ribonucleoside bisphosphate degradation													biological_process											owl:Class	
GO:2000647	biolink:NamedThing	negative regulation of stem cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.	got7fsn_ti							dph	2011-04-27T01:04:22Z						biological_process											owl:Class	
GO:0140270	biolink:NamedThing	gluconate import across plasma membrane	The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-10-01T08:47:35Z						biological_process											owl:Class	
GO:0001318	biolink:NamedThing	obsolete formation of oxidatively modified proteins involved in replicative cell aging	OBSOLETE. Chemical reaction, between proteins and reactive oxygen species, that occurs in dividing cells as they age and leads to a variety of changes in the affected proteins, including increases in protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.	got7fsn_ti	formation of oxidatively modified proteins during replicative cell ageing|formation of oxidatively modified proteins during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0051463	biolink:NamedThing	negative regulation of cortisol secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell.	got7fsn_ti	down regulation of cortisol secretion|downregulation of cortisol secretion|down-regulation of cortisol secretion|inhibition of cortisol secretion													biological_process											owl:Class	
GO:0034419	biolink:NamedThing	obsolete L-2-hydroxyglutarate oxidase activity	OBSOLETE. Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + hydrogen peroxide.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21950			This term was obsoleted because this activity is not believed to exist.	GO:0140696				True				molecular_function											owl:Class	
GO:0050850	biolink:NamedThing	positive regulation of calcium-mediated signaling	Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.	got7fsn_ti	upregulation of calcium-mediated signaling|up-regulation of calcium-mediated signaling|stimulation of calcium-mediated signaling|up regulation of calcium-mediated signaling|positive regulation of calcium-mediated signalling|activation of calcium-mediated signaling													biological_process											owl:Class	
GO:0044702	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0102131	biolink:NamedThing	obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity	OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxyglutaryl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-glutaryl-[acp] methyl ester.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21876			This term was obsoleted because it represents a specific substrate, and is beyond the specificity of GO.	GO:0004316				True				molecular_function											owl:Class	
GO:0023004	biolink:NamedThing	obsolete activation of dopamine receptor signaling pathway	OBSOLETE. Any process that initiates the dopamine receptor protein signaling pathway through stimulation of the dopamine receptor.	got7fsn_ti	stimulation of dopamine receptor signaling pathway|initiation of dopamine receptor signaling pathway|activation of dopamine receptor signaling pathway|activation of dopamine receptor signalling pathway				This term was made obsolete because the meaning of the term is ambiguous.	GO:0060161		2010-02-16T09:30:50Z		True				biological_process											owl:Class	
GO:0032551	biolink:NamedThing	pyrimidine ribonucleoside binding	Binding to a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose.	got7fsn_ti														molecular_function											owl:Class	
GO:0035338	biolink:NamedThing	long-chain fatty-acyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.	got7fsn_ti	long-chain fatty-acyl-CoA biosynthesis|long-chain fatty acyl CoA biosynthetic process|long-chain fatty-acyl-CoA synthesis|long-chain fatty-acyl-CoA anabolism|long-chain fatty-acyl-CoA formation						bf	2010-03-02T11:07:15Z						biological_process											owl:Class	
GO:0044046	biolink:NamedThing	obsolete interaction with host via substance released outside of symbiont	OBSOLETE. An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis.	got7fsn_ti	interaction with host via substance released outside of symbiont cells				This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True				biological_process											owl:Class	
GO:2000799	biolink:NamedThing	positive regulation of amniotic stem cell differentiation	Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation.	got7fsn_ti							yaf	2011-06-29T02:19:06Z						biological_process											owl:Class	
GO:0106178	biolink:NamedThing	obsolete translocase activity	OBSOLETE. Catalysis the movement of ions or molecules across membranes or their separation within membranes.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:41:06Z		True		EC:7.-.-.-		molecular_function											owl:Class	
GO:0032549	biolink:NamedThing	ribonucleoside binding	Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.	got7fsn_ti														molecular_function											owl:Class	
GO:1903232	biolink:NamedThing	melanosome assembly	The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.	got7fsn_ti	melanosome formation						bf	2014-07-31T10:41:38Z						biological_process											owl:Class	
GO:0048115	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000928	biolink:NamedThing	negative regulation of cellodextrin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process.	got7fsn_ti	negative regulation of cellodextrin catabolism						tt	2011-08-01T12:41:33Z						biological_process											owl:Class	
GO:0010562	biolink:NamedThing	positive regulation of phosphorus metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.	got7fsn_ti														biological_process											owl:Class	
GO:0051135	biolink:NamedThing	positive regulation of NK T cell activation	Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.	got7fsn_ti	upregulation of NK T cell activation|up regulation of NK T cell activation|positive regulation of NT cell activation|activation of NK T cell activation|positive regulation of NK T-cell activation|positive regulation of NKT cell activation|positive regulation of natural killer T cell activation|stimulation of NK T cell activation|positive regulation of NK T-lymphocyte activation|positive regulation of NK T lymphocyte activation|positive regulation of natural T cell activation|up-regulation of NK T cell activation													biological_process											owl:Class	
GO:1990602	biolink:NamedThing	obsolete importin alpha-subunit nuclear import complex	OBSOLETE. A trimeric protein complex which functions to transport the importin alpha-subunit into the nucleus through the nuclear pore to facilitate another round of mRNP incorporation and regulation. In Drosophila it consists of Cdm (Imp13), Mago and Tsu (Y14).	got7fsn_ti	Importin13-Mago-Tsu complex|Cdm-Mago-Tsu complex				The reason for obsoletion is that these terms include the substrate of the reaction.		bhm	2015-01-09T16:28:54Z		True				cellular_component											owl:Class	
GO:1902267	biolink:NamedThing	regulation of polyamine transmembrane transport	Any process that modulates the frequency, rate or extent of polyamine transmembrane transport.	got7fsn_ti							mcc	2013-06-28T21:34:36Z						biological_process											owl:Class	
GO:1901026	biolink:NamedThing	ripoptosome assembly involved in necroptotic process	The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process.	got7fsn_ti	ripoptosome assembly involved in necroptosis						pr	2012-06-19T08:54:28Z						biological_process											owl:Class	
GO:0052555	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003056	biolink:NamedThing	regulation of vascular associated smooth muscle contraction	Any process that increases the frequency, rate or extent of vascular smooth muscle contraction.	got7fsn_ti	regulation of vascular smooth muscle contraction													biological_process											owl:Class	
GO:0032567	biolink:NamedThing	dGTP binding	Binding to dGTP, deoxyguanosine triphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0032950	biolink:NamedThing	regulation of beta-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans.	got7fsn_ti	regulation of beta-glucan metabolism													biological_process											owl:Class	
GO:2000917	biolink:NamedThing	positive regulation of glucuronoxylan catabolic process	Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process.	got7fsn_ti	positive regulation of glucuronoxylan catabolism						tt	2011-07-29T07:54:50Z						biological_process											owl:Class	
CL:0000695	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904492	biolink:NamedThing	Ac-Asp-Glu binding	Binding to Ac-Asp-Glu.	got7fsn_ti							hal	2015-07-20T10:32:49Z						molecular_function											owl:Class	
CHEBI:60831	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071890	biolink:NamedThing	bicarbonate binding	Binding to bicarbonate ions (CHO3-).	got7fsn_ti	hydrogencarbonate binding|CHO3- ion binding binding						mah	2010-09-14T01:47:43Z						molecular_function											owl:Class	
GO:2000269	biolink:NamedThing	regulation of fibroblast apoptotic process	Any process that modulates the frequency, rate or extent of fibroblast apoptotic process.	got7fsn_ti	regulation of fibroblast apoptosis						jl	2010-11-23T01:07:23Z						biological_process											owl:Class	
GO:0052473	biolink:NamedThing	obsolete negative regulation by organism of symbiont B-cell mediated immune response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of symbiont B-cell mediated immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1905665	biolink:NamedThing	positive regulation of calcium ion import across plasma membrane	Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane.	got7fsn_ti	up regulation of calcium ion import across plasma membrane|up-regulation of calcium ion import across plasma membrane|upregulation of calcium ion import across plasma membrane|activation of calcium ion import across plasma membrane				An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay).		bhm	2016-11-11T09:26:23Z						biological_process											owl:Class	
GO:1904945	biolink:NamedThing	obsolete response to cobalt(II) acetate	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus.	got7fsn_ti					This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2016-02-02T16:47:52Z		True				biological_process											owl:Class	
CHEBI:24297	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902330	biolink:NamedThing	synthesis of RNA primer involved in bacterial-type DNA replication	Any synthesis of RNA primer that is involved in bacterial-type DNA replication.	got7fsn_ti	replication priming involved in bacterial-type DNA replication						jl	2013-07-25T10:48:18Z						biological_process											owl:Class	
GO:0004195	biolink:NamedThing	obsolete renin activity	OBSOLETE. Catalysis of the cleavage of Leu-Xaa bond in angiotensinogen to generate angiotensin I.	got7fsn_ti	angiotensin-forming enzyme activity|angiotensinogenase activity|renin activity			GO:0004190	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:22563	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000217	biolink:NamedThing	regulation of invasive growth in response to glucose limitation	Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation.	got7fsn_ti	regulation of colony morphology						mah	2010-11-03T04:35:56Z						biological_process											owl:Class	
CL:0000838	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042146	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901793	biolink:NamedThing	3-(3-hydroxyphenyl)propanoate metabolic process	The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate.	got7fsn_ti	3-(3-hydroxyphenyl)propanoate metabolism						yaf	2013-01-16T11:47:09Z						biological_process											owl:Class	
GO:1901724	biolink:NamedThing	positive regulation of cell proliferation involved in kidney development	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.	got7fsn_ti	activation of cell proliferation involved in kidney development|up regulation of cell proliferation involved in kidney development|up-regulation of cell proliferation involved in kidney development|upregulation of cell proliferation involved in kidney development						krc	2012-12-27T19:30:40Z						biological_process											owl:Class	
GO:1901339	biolink:NamedThing	regulation of store-operated calcium channel activity	Any process that modulates the frequency, rate or extent of store-operated calcium channel activity.	got7fsn_ti							pr	2012-09-03T14:23:10Z						biological_process											owl:Class	
GO:0014735	biolink:NamedThing	regulation of muscle atrophy	Any process that modulates the frequency, rate or extent of muscle atrophy.	got7fsn_ti														biological_process											owl:Class	
GO:0009481	biolink:NamedThing	obsolete aa3-type cytochrome c oxidase	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.	got7fsn_ti	aa3-type cytochrome c oxidase			GO:0004129	This term was made obsolete because it describes a class of gene products rather than a molecular function.					True				molecular_function											owl:Class	
GO:0046582	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046240	biolink:NamedThing	obsolete xylene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.	got7fsn_ti	xylene biosynthetic process|xylene formation|xylene synthesis|xylene anabolism|xylene biosynthesis			GO:0018948	This term was made obsolete because xylene is not synthesized by living organisms, and GO does not cover non-biological processes.					True				biological_process											owl:Class	
GO:0045652	biolink:NamedThing	regulation of megakaryocyte differentiation	Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0052141	biolink:NamedThing	obsolete positive chemotaxis on or near host	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0001936	biolink:NamedThing	regulation of endothelial cell proliferation	Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0030388	biolink:NamedThing	fructose 1,6-bisphosphate metabolic process	The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.	got7fsn_ti	fructose 1,6-bisphosphate metabolism													biological_process											owl:Class	
GO:0005328	biolink:NamedThing	neurotransmitter:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).	got7fsn_ti	sodium/neurotransmitter symporter activity													molecular_function											owl:Class	
GO:1990421	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:62920	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052447	biolink:NamedThing	obsolete modulation by organism of symbiont ethylene-mediated defense response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont ethylene-mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
UBERON:0003220	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000125	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051858	biolink:NamedThing	obsolete avoidance of symbiont defenses	OBSOLETE. Any process, either constitutive or induced, by which an organism evades, minimizes, or suppresses the effects of its symbiont organism's defense(s). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/14862			This term was made obsolete because it is not relevant for the host in a host-symbiont interaction.					True				biological_process											owl:Class	
GO:1900681	biolink:NamedThing	octadecene metabolic process	The chemical reactions and pathways involving octadecene.	got7fsn_ti	octadecene metabolism						tt	2012-05-22T04:28:28Z						biological_process											owl:Class	
GO:0046516	biolink:NamedThing	hypusine metabolic process	The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.	got7fsn_ti	hypusine metabolism													biological_process											owl:Class	
UBERON:0002038	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990921	biolink:NamedThing	obsolete proteasome localization to nuclear periphery	OBSOLETE. A process in which a proteasome is transported to, or maintained in, a location within the nuclear periphery.	got7fsn_ti	proteasome localisation to nuclear periphery				This term was obsoleted at the TermGenie Gatekeeper stage.		mah	2015-12-15T12:02:31Z		True				biological_process											owl:Class	
GO:0015842	biolink:NamedThing	aminergic neurotransmitter loading into synaptic vesicle	The active transport of aminergic neurotransmitters into a synaptic vesicle.  This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.	got7fsn_ti														biological_process											owl:Class	
GO:0010414	biolink:NamedThing	glucuronoarabinoxylan metabolic process	The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units.	got7fsn_ti	glucuronoarabinoxylan metabolism													biological_process											owl:Class	
UBERON:0004667	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051340	biolink:NamedThing	regulation of ligase activity	Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.	got7fsn_ti	ligase regulator													biological_process											owl:Class	
GO:2000877	biolink:NamedThing	negative regulation of oligopeptide transport	Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport.	got7fsn_ti							bf	2011-07-27T01:54:07Z						biological_process											owl:Class	
CHEBI:5017	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001368	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17544	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901748	biolink:NamedThing	leukotriene D4 metabolic process	The chemical reactions and pathways involving leukotriene D4.	got7fsn_ti	leukotriene D4 metabolism						yaf	2013-01-14T10:56:12Z						biological_process											owl:Class	
PR:000014717	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001815	biolink:NamedThing	positive regulation of antibody-dependent cellular cytotoxicity	Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity.	got7fsn_ti	positive regulation of antibody-dependent cell death|positive regulation of antibody-dependent cell killing|up-regulation of antibody-dependent cellular cytotoxicity|stimulation of antibody-dependent cellular cytotoxicity|activation of antibody-dependent cellular cytotoxicity|up regulation of antibody-dependent cellular cytotoxicity|positive regulation of antibody dependent cell killing|upregulation of antibody-dependent cellular cytotoxicity|positive regulation of antibody dependent cell death													biological_process											owl:Class	
GO:1905274	biolink:NamedThing	regulation of modification of postsynaptic actin cytoskeleton	Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton.	got7fsn_ti	regulation of postsynaptic actin cytoskeleton remodelling						dos	2016-06-16T22:34:25Z						biological_process											owl:Class	
GO:0099588	biolink:NamedThing	positive regulation of postsynaptic cytosolic calcium concentration	Any process that increases the concentration of calcium ions in the postsynaptic cytosol.	got7fsn_ti														biological_process											owl:Class	
GO:0005533	biolink:NamedThing	obsolete N-acetylgalactosamine lectin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	N-acetylgalactosamine lectin				This term was made obsolete because it refers to a class of gene products.	GO:0046871|GO:0007157				True				molecular_function											owl:Class	
GO:0046640	biolink:NamedThing	regulation of alpha-beta T cell proliferation	Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation.	got7fsn_ti	regulation of alpha-beta T-cell proliferation|regulation of alpha-beta T-lymphocyte proliferation|regulation of alpha-beta T lymphocyte proliferation													biological_process											owl:Class	
CL:0002573	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014859	biolink:NamedThing	negative regulation of skeletal muscle cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation.	got7fsn_ti														biological_process											owl:Class	
GO:0071299	biolink:NamedThing	cellular response to vitamin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.	got7fsn_ti	cellular response to retinol						mah	2009-12-10T04:29:30Z						biological_process											owl:Class	
CHEBI:16382	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030389	biolink:NamedThing	fructosamine metabolic process	The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.	got7fsn_ti	fructosamine metabolism													biological_process											owl:Class	
GO:0070202	biolink:NamedThing	regulation of establishment of protein localization to chromosome	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.	got7fsn_ti	regulation of establishment of protein localisation to chromosome													biological_process											owl:Class	
GO:0007237	biolink:NamedThing	obsolete activation of Ssk2/Ssk22 proteins	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of Ssk2/Ssk22 proteins				This term was made obsolete because it contains gene product and species specific information.					True				biological_process											owl:Class	
GO:0009498	biolink:NamedThing	obsolete bacterial-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	bacterial-type ferredoxin			GO:0009055	This term was made obsolete because it does not represent a function.					True				molecular_function											owl:Class	
GO:0035394	biolink:NamedThing	regulation of chemokine (C-X-C motif) ligand 9 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.	got7fsn_ti	regulation of CXCL9 production|regulation of MIG production						bf	2010-03-23T10:06:19Z						biological_process											owl:Class	
CHEBI:32529	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050946	biolink:NamedThing	positive regulation of xanthophore differentiation	Any process that activates or increases the frequency, rate or extent of xanthophore differentiation.	got7fsn_ti	up regulation of xanthophore differentiation|upregulation of xanthophore differentiation|up-regulation of xanthophore differentiation|stimulation of xanthophore differentiation|activation of xanthophore differentiation				Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure.									biological_process											owl:Class	
GO:0015841	biolink:NamedThing	chromaffin granule amine transport	The directed movement of amines into, out of or within chromaffin granules.	got7fsn_ti														biological_process											owl:Class	
GO:0008341	biolink:NamedThing	obsolete response to cocaine (sensu Insecta)	OBSOLETE. A change in state or activity of a mature individual as the result of a cocaine stimulus. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).	got7fsn_ti	response to cocaine (sensu Insecta)				This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.	GO:0048148				True				biological_process											owl:Class	
GO:0140314	biolink:NamedThing	calcium ion sequestering activity	The selective interaction of a protein with a calcium ion to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	got7fsn_ti							pg	2019-03-28T10:07:18Z						molecular_function											owl:Class	
GO:1905635	biolink:NamedThing	FACT complex assembly	The aggregation, arrangement and bonding together of a set of components to form a FACT complex.	got7fsn_ti	Facilitates chromatin transcription complex assembly|FACT complex formation|Facilitates chromatin transcription complex formation						pga	2016-11-02T15:06:03Z						biological_process											owl:Class	
GO:0070280	biolink:NamedThing	pyridoxal binding	Binding to pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.	got7fsn_ti														molecular_function											owl:Class	
GO:0009097	biolink:NamedThing	isoleucine biosynthetic process	The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.	got7fsn_ti	isoleucine biosynthesis|isoleucine synthesis|isoleucine formation|isoleucine anabolism											MetaCyc:ILEUSYN-PWY		biological_process											owl:Class	
GO:0042053	biolink:NamedThing	regulation of dopamine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.	got7fsn_ti	regulation of dopamine metabolism													biological_process											owl:Class	
GO:0044138	biolink:NamedThing	obsolete modulation of development of symbiont on or near host	OBSOLETE. Any process in which the symbiont regulates its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	got7fsn_ti					The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-04T04:24:25Z		True				biological_process											owl:Class	
GO:1904317	biolink:NamedThing	cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.	got7fsn_ti	cellular response to PAF|cellular response to platelet-activating factor						sl	2015-06-10T18:10:23Z						biological_process											owl:Class	
UBERON:0003054	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071801	biolink:NamedThing	regulation of podosome assembly	Any process that modulates the frequency, rate or extent of podosome assembly.	got7fsn_ti					Note that the assembly is regulated by several small GTPases of the Rab and Rho families.		mah	2010-09-03T01:34:29Z						biological_process											owl:Class	
GO:0046391	biolink:NamedThing	5-phosphoribose 1-diphosphate metabolic process	The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.	got7fsn_ti	PRPP metabolic process|5-phosphoribose 1-diphosphate metabolism											MetaCyc:PRPP-PWY		biological_process											owl:Class	
GO:0051070	biolink:NamedThing	galactomannan biosynthetic process	The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.	got7fsn_ti	galactomannan synthesis|galactomannan biosynthesis|galactomannan formation|galactomannan anabolism													biological_process											owl:Class	
GO:0052196	biolink:NamedThing	obsolete negative regulation by host of symbiont defense response	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	inhibition by host of symbiont defense response|downregulation by host of symbiont defense response|down regulation by host of symbiont defense response|down-regulation by host of symbiont defense response	https://github.com/geneontology/go-ontology/issues/14862			This term was made obsolete because it is not relevant for the host in a host-symbiont interaction.					True				biological_process											owl:Class	
GO:0010830	biolink:NamedThing	regulation of myotube differentiation	Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	got7fsn_ti														biological_process											owl:Class	
CHEBI:21763	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903596	biolink:NamedThing	regulation of gap junction assembly	Any process that modulates the frequency, rate or extent of gap junction assembly.	got7fsn_ti							rl	2014-11-07T18:51:36Z						biological_process											owl:Class	
GO:0000362	biolink:NamedThing	obsolete first U2-type spliceosomal transesterification activity	OBSOLETE. Catalysis of the first transesterification reaction of U2-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6 and/or U2 snRNA, and/or associated proteins.	got7fsn_ti	first U2-type spliceosomal transesterification activity|lariat formation, 5'-splice site cleavage			GO:0000384	This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.					True				molecular_function											owl:Class	
GO:0015310	biolink:NamedThing	benomyl:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out).	got7fsn_ti	benomyl:hydrogen antiporter activity													molecular_function											owl:Class	
PO:0025164	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903662	biolink:NamedThing	L-altrarate metabolic process	The chemical reactions and pathways involving L-altrarate.	got7fsn_ti	L-altrarate(1-) metabolism						jl	2014-11-26T14:34:20Z						biological_process											owl:Class	
CHEBI:17051	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010656	biolink:NamedThing	negative regulation of muscle cell apoptotic process	Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.	got7fsn_ti	negative regulation of muscle cell apoptosis													biological_process											owl:Class	
GO:0140540	biolink:NamedThing	negative regulation melanotic encapsulation of foreign target	Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/16749					pg	2020-11-07T08:17:40Z						biological_process											owl:Class	
GO:0003154	biolink:NamedThing	BMP signaling pathway involved in determination of left/right symmetry	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the determination of left/right symmetry.	got7fsn_ti	BMP signalling pathway involved in determination of left/right symmetry|BMP signaling pathway involved in determination of left/right asymmetry						tb	2009-09-24T05:34:57Z						biological_process											owl:Class	
GO:0016145	biolink:NamedThing	S-glycoside catabolic process	The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.	got7fsn_ti	S-glycoside degradation|S-glycoside breakdown|thioglycoside catabolic process|S-glycoside catabolism|thioglycoside catabolism													biological_process											owl:Class	
GO:0048683	biolink:NamedThing	regulation of collateral sprouting of intact axon in response to injury	Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.	got7fsn_ti														biological_process											owl:Class	
GO:0030051	biolink:NamedThing	obsolete FK506-sensitive peptidyl-prolyl cis-trans isomerase	OBSOLETE. Interacts selectively with the immunosuppressant FK506, and possesses peptidyl-prolyl isomerase activity (catalysis of the reaction: peptidoproline (omega=180) = peptidylproline (omega=0)).	got7fsn_ti	FK506 binding protein|FKBP|FK506-sensitive peptidyl-prolyl cis-trans isomerase				This term was made obsolete because it represents a gene product and not a function.	GO:0003755|GO:0005528				True				molecular_function											owl:Class	
GO:0016563	biolink:NamedThing	obsolete transcription activator activity	OBSOLETE. Any transcription regulator activity required for initiation or upregulation of transcription.	got7fsn_ti	transcriptional activator activity|transcription activator activity|transcription activating factor			GO:0001228	This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.					True	GO:0003710			molecular_function											owl:Class	
PO:0000030	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051067	biolink:NamedThing	dihydropteridine metabolic process	The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.	got7fsn_ti	dihydropteridine reduction|dihydropteridine metabolism|6,7-dihydropteridine metabolic process													biological_process											owl:Class	
GO:1903341	biolink:NamedThing	regulation of meiotic DNA double-strand break formation	Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation.	got7fsn_ti							mcc	2014-08-18T21:31:54Z						biological_process											owl:Class	
GO:0042576	biolink:NamedThing	obsolete aspartyl aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.	got7fsn_ti	aspartyl aminopeptidase activity			GO:0004177	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:2001140	biolink:NamedThing	positive regulation of phospholipid transport	Any process that activates or increases the frequency, rate or extent of phospholipid transport.	got7fsn_ti							kmv	2011-10-14T06:16:14Z						biological_process											owl:Class	
GO:0002648	biolink:NamedThing	positive regulation of central tolerance induction	Any process that activates or increases the frequency, rate, or extent of central tolerance induction.	got7fsn_ti	upregulation of central tolerance induction|up-regulation of central tolerance induction|activation of central tolerance induction|up regulation of central tolerance induction|stimulation of central tolerance induction													biological_process											owl:Class	
GO:0052466	biolink:NamedThing	obsolete modulation by organism of symbiont resistance gene-dependent defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont gene-for-gene resistance|modulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|modulation by organism of defense response in symbiont by specific elicitors|modulation by organism of symbiont resistance gene-dependent defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:1903932	biolink:NamedThing	regulation of DNA primase activity	Any process that modulates the frequency, rate or extent of DNA primase activity.	got7fsn_ti							mah	2015-02-12T14:28:26Z						biological_process											owl:Class	
GO:1902385	biolink:NamedThing	glycyrrhetinate catabolic process	The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate.	got7fsn_ti	glycyrrhetinate catabolism|glycyrrhetinate degradation|glycyrrhetinate breakdown						ms	2013-09-03T12:56:10Z						biological_process											owl:Class	
GO:2000524	biolink:NamedThing	negative regulation of T cell costimulation	Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation.	got7fsn_ti	negative regulation of T cell co-stimulation|negative regulation of T lymphocyte costimulation|negative regulation of T-cell co-stimulation|negative regulation of T-cell costimulation|negative regulation of T-lymphocyte costimulation						ebc	2011-03-23T10:23:31Z						biological_process											owl:Class	
GO:0071623	biolink:NamedThing	negative regulation of granulocyte chemotaxis	Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.	got7fsn_ti							mah	2010-02-09T04:13:19Z						biological_process											owl:Class	
GO:1902471	biolink:NamedThing	regulation of mitotic actomyosin contractile ring localization	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring localization.	got7fsn_ti							mah	2013-10-24T14:20:03Z						biological_process											owl:Class	
GO:0140217	biolink:NamedThing	positive regulation of D-aspartate import across plasma membrane	Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15041					pg	2018-04-11T15:45:22Z						biological_process											owl:Class	
GO:0150066	biolink:NamedThing	negative regulation of deacetylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity.	got7fsn_ti							bc	2018-07-23T12:37:57Z						biological_process											owl:Class	
GO:2000454	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.	got7fsn_ti							bf	2011-03-04T10:45:52Z						biological_process											owl:Class	
GO:0032721	biolink:NamedThing	negative regulation of lymphotoxin A production	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production.	got7fsn_ti	negative regulation of tumor necrosis factor-beta production|down-regulation of lymphotoxin A production|negative regulation of lymphotoxin-alpha production|downregulation of lymphotoxin A production|negative regulation of TNF-beta production|inhibition of lymphotoxin A production|negative regulation of lymphotoxin A biosynthetic process|negative regulation of LTA production|down regulation of lymphotoxin A production										GO:0043018			biological_process											owl:Class	
GO:0016351	biolink:NamedThing	obsolete drug susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	drug susceptibility/resistance			GO:0009410	This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True				biological_process											owl:Class	
GO:0042844	biolink:NamedThing	glycol metabolic process	The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.	got7fsn_ti	glycol metabolism|dihydric alcohol metabolic process|dihydric alcohol metabolism													biological_process											owl:Class	
GO:0043215	biolink:NamedThing	daunorubicin transport	The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0018540	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902541	biolink:NamedThing	multi-organism micropinocytosis	A micropinocytosis which involves another organism.	got7fsn_ti							bf	2013-12-02T14:26:39Z						biological_process											owl:Class	
GO:0004116	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072343	biolink:NamedThing	pancreatic stellate cell proliferation	The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus.	got7fsn_ti							mah	2010-11-05T03:04:50Z						biological_process											owl:Class	
GO:0110081	biolink:NamedThing	negative regulation of placenta blood vessel development	Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.	got7fsn_ti							kmv	2018-02-01T15:01:11Z						biological_process											owl:Class	
GO:0032791	biolink:NamedThing	lead ion binding	Binding to lead (Pb) ions.	got7fsn_ti														molecular_function											owl:Class	
GO:2000802	biolink:NamedThing	positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.	got7fsn_ti	positive regulation of endocardial cushion to mesenchymal transition involved in valve formation						bf	2011-07-01T12:31:25Z						biological_process											owl:Class	
GO:0009318	biolink:NamedThing	exodeoxyribonuclease VII complex	An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA.	got7fsn_ti														cellular_component											owl:Class	
PO:0006041	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000704	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33871	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33832	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904937	biolink:NamedThing	sensory neuron migration	The orderly movement of a sensory neuron from one site to another.	got7fsn_ti							ah	2016-02-01T14:15:50Z						biological_process											owl:Class	
GO:1905564	biolink:NamedThing	positive regulation of vascular endothelial cell proliferation	Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.	got7fsn_ti	up-regulation of vascular endothelial cell proliferation|up regulation of vascular endothelial cell proliferation|upregulation of vascular endothelial cell proliferation|activation of vascular endothelial cell proliferation						nc	2016-10-17T09:24:35Z						biological_process											owl:Class	
CHEBI:26337	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033319	biolink:NamedThing	UDP-D-xylose metabolic process	The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-D-xylose metabolism													biological_process											owl:Class	
OBO:GOCHE_35703	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009580	biolink:NamedThing	obsolete thylakoid (sensu Bacteria)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	thylakoid (sensu Bacteria)				This term was made obsolete because more specific children exist.	GO:0042716|GO:0030075				True				cellular_component											owl:Class	
GO:2000011	biolink:NamedThing	regulation of adaxial/abaxial pattern formation	Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation.	got7fsn_ti	regulation of adaxial/abaxial pattern specification						tb	2010-08-05T11:20:22Z						biological_process											owl:Class	
CHEBI:77444	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002520	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032938	biolink:NamedThing	negative regulation of translation in response to oxidative stress	Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	got7fsn_ti														biological_process											owl:Class	
OIO:consider	biolink:NamedThing	consider		got7fsn_ti																									owl:AnnotationProperty	
GO:0015822	biolink:NamedThing	ornithine transport	The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	L-ornithine transport													biological_process											owl:Class	
GO:0005156	biolink:NamedThing	obsolete epidermal growth factor receptor inhibiting ligand activity	OBSOLETE. This term was not defined before being made obsolete.	got7fsn_ti	EGFR inhibiting ligand activity|epidermal growth factor receptor inhibiting ligand activity|EGF receptor inhibiting ligand activity			GO:0005154	This term was made obsolete because it represents both a biological process and a molecular function.	GO:0007175|GO:0030293				True				molecular_function											owl:Class	
GO:0044287	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905185	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:22565	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035559	biolink:NamedThing	obsolete MAPKKK cascade involved in epidermal growth factor receptor signaling	OBSOLETE. The process in which a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	got7fsn_ti	MAPKKK cascade involved in signaling from the EGFR|MAPKKK cascade involved in epidermal growth factor receptor signalling|MAPKKK cascade involved in epidermal growth factor receptor signaling				This term was made obsolete because the syntax of the term is incorrect.	GO:0038029	bf	2010-05-14T01:53:15Z		True				biological_process											owl:Class	
GO:0032325	biolink:NamedThing	molybdopterin cofactor catabolic process	The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.	got7fsn_ti														biological_process											owl:Class	
GO:0045093	biolink:NamedThing	obsolete interleukin-18 alpha subunit binding	OBSOLETE. Binding to alpha subunit of interleukin-18. IL-18a is a component of IL-18 that is essential for IL-18 binding on the surface of T-helper 1 cells.	got7fsn_ti	IL-18Ra binding				This term was obsoleted because interleukin-18 is a single polypeptide and has no subunits					True				molecular_function											owl:Class	
GO:0043544	biolink:NamedThing	lipoamide binding	Binding to lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.	got7fsn_ti														molecular_function											owl:Class	
GO:0004202	biolink:NamedThing	obsolete caspase-2 activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	caspase-2 activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:27092	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_38867	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150164	biolink:NamedThing	miRNA-mediated regulation of transcription by RNA polymerase II	Any process mediated by a microRNA (miRNA) that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti							bc	2020-01-14T12:16:32Z						biological_process											owl:Class	
GO:0004443	biolink:NamedThing	obsolete inositol-1,4,-bisphosphate 4-phosphatase	OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4-bisphosphate + H2O = D-myo-inositol 3-monophosphate + phosphate.	got7fsn_ti	inositol-1,4,-bisphosphate 4-phosphatase					GO:0016316				True				molecular_function											owl:Class	
GO:0106104	biolink:NamedThing	regulation of glutamate receptor clustering	Any process that modulates the frequency, rate or extent of glutamate receptor clustering.	got7fsn_ti							hjd	2018-03-06T15:54:33Z						biological_process											owl:Class	
GO:0060146	biolink:NamedThing	obsolete host gene silencing in virus induced gene silencing	OBSOLETE. The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19958			The reason for obsoletion is there there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0051163	biolink:NamedThing	D-arabitol metabolic process	The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.	got7fsn_ti	D-arabitol metabolism													biological_process											owl:Class	
GO:0010519	biolink:NamedThing	negative regulation of phospholipase activity	Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.	got7fsn_ti														biological_process											owl:Class	
GO:0098752	biolink:NamedThing	integral component of the cytoplasmic side of the plasma membrane	The component of the plasma membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0060282	biolink:NamedThing	positive regulation of oocyte development	Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
PO:0000077	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099029	biolink:NamedThing	anchored component of presynaptic active zone membrane	The component of the presynaptic active zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
OBO:OBA_0000161	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000926	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46957	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071878	biolink:NamedThing	negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.	got7fsn_ti	negative regulation of adrenergic receptor signalling pathway|negative regulation of adrenergic receptor signaling pathway						mah	2010-09-13T04:15:34Z						biological_process											owl:Class	
GO:0004218	biolink:NamedThing	obsolete cathepsin S activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin L, but with much less activity on the terminal bond of Z-Phe-Arg-NHMec, and more activity on the terminal bond of Z-Val-Val-Arg-Xaa compounds.	got7fsn_ti	cathepsin S activity			GO:0004197	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0043475	biolink:NamedThing	pigment metabolic process involved in pigment accumulation	The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment.	got7fsn_ti	pigment metabolic process during pigment accumulation|pigment metabolism during pigment accumulation													biological_process											owl:Class	
GO:0001803	biolink:NamedThing	regulation of type III hypersensitivity	Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response.	got7fsn_ti														biological_process											owl:Class	
CHEBI:29678	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24261	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28940	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043210	biolink:NamedThing	alkanesulfonate binding	Binding to alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.	got7fsn_ti														molecular_function											owl:Class	
GO:0072628	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:46966	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005907	biolink:NamedThing	obsolete HA1 clathrin adaptor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	HA1 clathrin adaptor|AP1				This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous.	GO:0030121				True				cellular_component											owl:Class	
GO:0100004	biolink:NamedThing	obsolete positive regulation of peroxisome organization by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates peroxisome organization.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
CHEBI:35189	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15333	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046909	biolink:NamedThing	obsolete intermembrane transport	OBSOLETE. The directed movement of substances between any membrane of a cell, including the plasma membrane and its regions.	got7fsn_ti					The reason for obsoletion is that this term was incorrectly named, defined, and placed in the ontology, and thus had been used to annotate two unrelated processes of [intermembrane lipid transfer] and processes related to [vesicular transport]. It was also inappropriately used as the parent term for [protein transport from ciliary membrane to plasma membrane], which has already been moved to an appropriate location as a child of [protein transport within lipid bilayer].	GO:0016192|GO:0120009				True				biological_process											owl:Class	
GO:0003368	biolink:NamedThing	cell-matrix adhesion involved in mesendodermal cell migration	The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell.	got7fsn_ti							dph	2009-12-08T05:26:12Z						biological_process											owl:Class	
GO:0061874	biolink:NamedThing	positive regulation of hepatic stellate cell contraction	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction.	got7fsn_ti							dph	2017-05-01T13:29:30Z						biological_process											owl:Class	
GO:0070061	biolink:NamedThing	fructose binding	Binding to the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.	got7fsn_ti														molecular_function											owl:Class	
GO:0090410	biolink:NamedThing	malonate catabolic process	The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion.	got7fsn_ti							tb	2011-06-10T01:53:43Z						biological_process											owl:Class	
GO:0009201	biolink:NamedThing	ribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	ribonucleoside triphosphate synthesis|ribonucleoside triphosphate anabolism|ribonucleoside triphosphate formation|ribonucleoside triphosphate biosynthesis													biological_process											owl:Class	
GO:0090374	biolink:NamedThing	oligopeptide export from mitochondrion	The process in which an oligopeptide is transported out of the mitochondrial matrix. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	got7fsn_ti							tb	2010-08-27T04:38:18Z						biological_process											owl:Class	
GO:0031440	biolink:NamedThing	regulation of mRNA 3'-end processing	Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.	got7fsn_ti														biological_process											owl:Class	
GO:1904339	biolink:NamedThing	negative regulation of dopaminergic neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation.	got7fsn_ti	down regulation of dopaminergic neuron differentiation|downregulation of dopaminergic neuron differentiation|inhibition of dopaminergic neuron differentiation|down-regulation of dopaminergic neuron differentiation						sl	2015-06-11T18:06:25Z						biological_process											owl:Class	
UBERON:0003657	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902393	biolink:NamedThing	negative regulation of exodeoxyribonuclease activity	Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity.	got7fsn_ti	inhibition of exodeoxyribonuclease activity|down-regulation of exodeoxyribonuclease activity|downregulation of exodeoxyribonuclease activity|down regulation of exodeoxyribonuclease activity						jl	2013-09-11T14:56:23Z						biological_process											owl:Class	
GO:0001302	biolink:NamedThing	obsolete replicative cell aging	OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.	got7fsn_ti	replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.	GO:0090399				True				biological_process											owl:Class	
UBERON:0006190	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030481	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044063	biolink:NamedThing	modulation by symbiont of host nervous system process	The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.	got7fsn_ti	regulation by symbiont of host neurological system process|modulation by symbiont of host neurological system process													biological_process											owl:Class	
PO:0025034	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033234	biolink:NamedThing	negative regulation of protein sumoylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.	got7fsn_ti	negative regulation of sumoylation													biological_process											owl:Class	
GO:0089708	biolink:NamedThing	L-histidine transmembrane export from vacuole	The directed movement of L-histidine out of the vacuole, across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
GO:0007123	biolink:NamedThing	obsolete bud scar accumulation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	bud scar accumulation				This term was made obsolete because it is a phenotype rather than a biological process.	GO:0000282				True				biological_process											owl:Class	
GO:0010680	biolink:NamedThing	obsolete cinnamic acid biosynthetic process involved in coumarin metabolism	OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.					True				biological_process											owl:Class	
GO:0015198	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:26739	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075276	biolink:NamedThing	regulation of telium development	Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.	got7fsn_ti														biological_process											owl:Class	
GO:0120177	biolink:NamedThing	negative regulation of torso signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway.	got7fsn_ti							krc	2018-06-07T16:58:08Z						biological_process											owl:Class	
GO:1900175	biolink:NamedThing	regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.	got7fsn_ti	regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry						bf	2012-03-09T10:39:10Z						biological_process											owl:Class	
GO:0071583	biolink:NamedThing	negative regulation of zinc ion transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.	got7fsn_ti	negative regulation of zinc ion membrane transport						mah	2010-01-28T03:15:54Z						biological_process											owl:Class	
CHEBI:17761	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048051	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:64609	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58779	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046621	biolink:NamedThing	negative regulation of organ growth	Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.	got7fsn_ti														biological_process											owl:Class	
OBO:GOCHE_26115	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901088	biolink:NamedThing	benzylpenicillin biosynthetic process	The chemical reactions and pathways resulting in the formation of benzylpenicillin.	got7fsn_ti	penicillin G formation|benzylpenicillin biosynthesis|benzylpenicillin anabolism|penicillin G anabolism|benzylpenicillin synthesis|benzylpenicillin formation|penicillin G biosynthesis|penicillin G synthesis						yaf	2012-07-05T10:29:07Z						biological_process											owl:Class	
GO:0052433	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902922	biolink:NamedThing	poly(3-hydroxyvalerate) metabolic process	The chemical reactions and pathways involving poly(3-hydroxyvalerate).	got7fsn_ti	poly(3-hydroxyvalerate) metabolism						tt	2014-04-21T19:13:56Z						biological_process											owl:Class	
CHEBI:37537	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002691	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035504	biolink:NamedThing	regulation of myosin light chain kinase activity	Any process that modulates the frequency, rate or extent of myosin light chain kinase activity.	got7fsn_ti							bf	2010-04-30T10:47:11Z						biological_process											owl:Class	
GO:1900177	biolink:NamedThing	regulation of aflatoxin biosynthetic process	Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process.	got7fsn_ti	regulation of aflatoxin biosynthesis|regulation of aflatoxin synthesis|regulation of aflatoxin formation|regulation of aflatoxin anabolism						di	2012-03-09T11:23:35Z						biological_process											owl:Class	
CHEBI:506227	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060699	biolink:NamedThing	regulation of endoribonuclease activity	Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.	got7fsn_ti							dph	2009-06-08T02:43:10Z						biological_process											owl:Class	
CHEBI:57590	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020047	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016067	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070796	biolink:NamedThing	regulation of cleistothecium development	Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	got7fsn_ti							mah	2009-07-08T03:30:04Z						biological_process											owl:Class	
GO:0110002	biolink:NamedThing	regulation of tRNA methylation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation.	got7fsn_ti							kmv							biological_process											owl:Class	
CHEBI:64499	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071389	biolink:NamedThing	cellular response to mineralocorticoid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.	got7fsn_ti							mah	2009-12-11T03:59:02Z						biological_process											owl:Class	
GO:1900276	biolink:NamedThing	regulation of proteinase activated receptor activity	Any process that modulates the frequency, rate or extent of proteinase activated receptor activity.	got7fsn_ti							rl	2012-04-04T01:31:20Z						biological_process											owl:Class	
PR:000001497	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903093	biolink:NamedThing	regulation of protein K48-linked deubiquitination	Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination.	got7fsn_ti							bf	2014-06-03T12:27:48Z						biological_process											owl:Class	
PR:000001141	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075078	biolink:NamedThing	obsolete modulation by host of symbiont receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:2000066	biolink:NamedThing	positive regulation of cortisol biosynthetic process	Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process.	got7fsn_ti	positive regulation of cortisol anabolism|positive regulation of cortisol synthesis|positive regulation of cortisol biosynthesis|positive regulation of cortisol formation						jl	2010-08-20T01:51:32Z						biological_process											owl:Class	
GO:2000533	biolink:NamedThing	negative regulation of renal albumin absorption	Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption.	got7fsn_ti							pr	2011-03-24T03:28:11Z						biological_process											owl:Class	
GO:0032552	biolink:NamedThing	deoxyribonucleotide binding	Binding to a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:70790	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000129	biolink:NamedThing	negative regulation of octopamine signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway.	got7fsn_ti	negative regulation of octopamine signalling pathway						mah	2010-09-29T09:29:44Z						biological_process											owl:Class	
GO:0016118	biolink:NamedThing	carotenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.	got7fsn_ti	carotenoid catabolism|carotenoid breakdown|carotenoid degradation													biological_process											owl:Class	
GO:0046800	biolink:NamedThing	obsolete enhancement of virulence	OBSOLETE. Any process that activates or increases the severity of viral infection and subsequent disease.	got7fsn_ti	enhancement of virulence				This term was made obsolete because 'virulence' is not a biological process; however, alteration of virulence also does not fit under 'regulation of biological quality ; GO:0065008' because it is a product both of the genotype/phenotype of the infecting organism and the genotype/phenotype of the organism being infected and varies by individual within a species both for the infecting organism and the infected organism.					True				biological_process											owl:Class	
GO:2001316	biolink:NamedThing	kojic acid metabolic process	The chemical reactions and pathways involving kojic acid.	got7fsn_ti	5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolism|kojic acid metabolism|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolic process|C6H6O4 metabolic process|C6H6O4 metabolism						bf	2012-04-18T09:22:42Z						biological_process											owl:Class	
GO:0051162	biolink:NamedThing	L-arabitol metabolic process	The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.	got7fsn_ti	L-arabitol metabolism													biological_process											owl:Class	
GO:1905509	biolink:NamedThing	protein localization to interphase microtubule organizing center	A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center.	got7fsn_ti	protein localisation to interphase microtubule organizing center|protein localisation in interphase microtubule organizing center|protein localization in interphase microtubule organizing center						mah	2016-09-28T12:32:24Z						biological_process											owl:Class	
GO:1903110	biolink:NamedThing	regulation of single-strand break repair via homologous recombination	Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination.	got7fsn_ti							pr	2014-06-09T12:11:26Z						biological_process											owl:Class	
GO:0045559	biolink:NamedThing	obsolete TRAIL receptor 2 biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of TRAIL-R2 (TNF-related apoptosis inducing ligand receptor 2), which engages a caspase-dependent apoptotic pathway and mediates apoptosis via the intracellular adaptor molecule FADD/MORT1.	got7fsn_ti	TRAIL receptor 2 formation|TRAIL receptor 2 synthesis|TRAIL receptor 2 biosynthesis|tumor necrosis factor receptor superfamily member 10B biosynthetic process|TRAIL receptor 2 anabolism	https://github.com/geneontology/go-ontology/issues/19900			The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True				biological_process											owl:Class	
GO:1900192	biolink:NamedThing	positive regulation of single-species biofilm formation	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation.	got7fsn_ti	activation of single-species biofilm formation|up-regulation of single-species biofilm formation|up regulation of single-species biofilm formation|upregulation of single-species biofilm formation						di	2012-03-19T12:42:21Z						biological_process											owl:Class	
CL:0002350	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901520	biolink:NamedThing	aspyridone B catabolic process	The chemical reactions and pathways resulting in the breakdown of aspyridone B.	got7fsn_ti	aspyridone B breakdown|aspyridone B catabolism|aspyridone B degradation						di	2012-10-18T18:31:44Z						biological_process											owl:Class	
GO:0015223	biolink:NamedThing	obsolete vitamin or cofactor transporter activity	OBSOLETE. Enables the directed transport of vitamins or cofactors into, out of or within a cell, or between cells.	got7fsn_ti	vitamin or cofactor transporter activity|vitamin/cofactor transporter activity				This term was made obsolete because it was replaced by more specific terms.	GO:0090482				True				molecular_function											owl:Class	
GO:0042888	biolink:NamedThing	molybdenum ion transmembrane transporter activity	Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:27933	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000903	biolink:NamedThing	cellooligosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide.	got7fsn_ti	cellooligosaccharide catabolism						jl	2011-07-28T03:21:49Z						biological_process											owl:Class	
GO:1901612	biolink:NamedThing	cardiolipin binding	Binding to cardiolipin.	got7fsn_ti							kmv	2012-11-12T21:19:50Z						molecular_function											owl:Class	
GO:0000763	biolink:NamedThing	obsolete cell morphogenesis involved in unidirectional conjugation	OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo unidirectional conjugation.	got7fsn_ti	cell morphogenesis involved in unidirectional conjugation				This term was made obsolete because unidirectional conjugation occurs only in prokaryotes, which do not undergo morphogenetic changes associated with conjugation. In short, the process described by this term does not occur.					True				biological_process											owl:Class	
CHEBI:25523	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902596	biolink:NamedThing	negative regulation of DNA replication origin binding	Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding.	got7fsn_ti	inhibition of DNA replication origin binding|downregulation of DNA replication origin binding|inhibition of ARS binding|down regulation of DNA replication origin binding|downregulation of ARS binding|negative regulation of ARS binding|down-regulation of DNA replication origin binding|down regulation of ARS binding|down-regulation of ARS binding						mah	2013-12-19T16:19:48Z						biological_process											owl:Class	
GO:0046321	biolink:NamedThing	positive regulation of fatty acid oxidation	Any process that activates or increases the frequency, rate or extent of fatty acid oxidation.	got7fsn_ti	stimulation of fatty acid oxidation|activation of fatty acid oxidation|up regulation of fatty acid oxidation|up-regulation of fatty acid oxidation|upregulation of fatty acid oxidation													biological_process											owl:Class	
CHEBI:74969	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032526	biolink:NamedThing	response to retinoic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.	got7fsn_ti	response to vitamin A acid													biological_process											owl:Class	
GO:0032193	biolink:NamedThing	ubiquinone biosynthetic process via 2-polyprenylphenol	The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol.	got7fsn_ti														biological_process											owl:Class	
UBERON:0000044	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060853	biolink:NamedThing	Notch signaling pathway involved in arterial endothelial cell fate commitment	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.	got7fsn_ti	Notch signalling pathway involved in arterial endothelial cell fate commitment						dph	2009-08-12T11:54:49Z						biological_process											owl:Class	
GO:0046220	biolink:NamedThing	pyridine biosynthetic process	The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.	got7fsn_ti	pyridine synthesis|pyridine biosynthesis|pyridine anabolism|pyridine formation													biological_process											owl:Class	
GO:0003932	biolink:NamedThing	obsolete SAR small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	got7fsn_ti	SAR small monomeric GTPase activity			GO:0003924	This term was made obsolete because it represents a gene product.	GO:0046903				True				molecular_function											owl:Class	
GO:0061961	biolink:NamedThing	positive regulation of heme oxygenase activity	Any process that activates or increases the frequency or rate of heme oxygenase activity.	got7fsn_ti							dph	2018-01-22T20:32:05Z						biological_process											owl:Class	
GO:1902118	biolink:NamedThing	calcidiol binding	Binding to calcidiol.	got7fsn_ti	calcifediol binding|25-hydroxyvitamin D3 binding|25OHD3 binding|25(OH)D3 binding|25-hydroxycholecalciferol binding						bf	2013-05-15T14:55:58Z						molecular_function											owl:Class	
PR:000001206	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007063	biolink:NamedThing	regulation of sister chromatid cohesion	Any process that modulates the frequency, rate or extent of sister chromatid cohesion.	got7fsn_ti														biological_process											owl:Class	
GO:0006923	biolink:NamedThing	obsolete cleavage of cytoskeletal proteins involved in execution phase of apoptosis	OBSOLETE. The proteolytic degradation of cytoskeletal proteins that contributes to apoptosis, leading to the collapse of cytoskeletal structures.	got7fsn_ti	apoptotic cleavage of cytoskeletal proteins|cleavage of cytoskeletal proteins involved in execution phase of apoptosis|cleavage of cytoskeletal proteins involved in apoptosis				This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'.	GO:0097200				True				biological_process											owl:Class	
GO:0002865	biolink:NamedThing	negative regulation of acute inflammatory response to antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.	got7fsn_ti	down regulation of acute inflammatory response to antigenic stimulus|downregulation of acute inflammatory response to antigenic stimulus|inhibition of acute inflammatory response to antigenic stimulus|down-regulation of acute inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:1904952	biolink:NamedThing	hydroxycinnamic acid transport	The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							lr	2016-02-05T22:00:38Z						biological_process											owl:Class	
GO:0043307	biolink:NamedThing	eosinophil activation	The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti														biological_process											owl:Class	
GO:0019529	biolink:NamedThing	taurine catabolic process	The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.	got7fsn_ti	taurine breakdown|taurine degradation|taurine catabolism											MetaCyc:TAURINEDEG-PWY		biological_process											owl:Class	
GO:1905785	biolink:NamedThing	negative regulation of anaphase-promoting complex-dependent catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.	got7fsn_ti							vw	2017-01-09T10:16:23Z						biological_process											owl:Class	
GO:0005670	biolink:NamedThing	obsolete transcription-activating factor, 30kD	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	transcription-activating factor, 30kD			GO:0005669	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:0075225	biolink:NamedThing	negative regulation of sporangium germination	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination.	got7fsn_ti	negative regulation of sporangium germination on or near host													biological_process											owl:Class	
GO:0002669	biolink:NamedThing	positive regulation of T cell anergy	Any process that activates or increases the frequency, rate, or extent of T cell anergy.	got7fsn_ti	up-regulation of T cell anergy|up regulation of T cell anergy|upregulation of T cell anergy|activation of T cell anergy|positive regulation of T-cell anergy|stimulation of T cell anergy|positive regulation of T-lymphocyte anergy|positive regulation of T lymphocyte anergy													biological_process											owl:Class	
PO:0006343	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099150	biolink:NamedThing	regulation of postsynaptic specialization assembly	Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization.	got7fsn_ti							dos	2017-07-05T13:20:48Z						biological_process											owl:Class	
GO:0005320	biolink:NamedThing	obsolete apolipoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	apolipoprotein				This term was made obsolete because it does not represent a molecular function.	GO:0005319				True	GO:0015907			molecular_function											owl:Class	
GO:1900294	biolink:NamedThing	regulation of heptasaccharide transport	Any process that modulates the frequency, rate or extent of heptasaccharide transport.	got7fsn_ti							tt	2012-04-05T07:40:40Z						biological_process											owl:Class	
CHEBI:22894	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014879	biolink:NamedThing	detection of electrical stimulus involved in regulation of muscle adaptation	The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.	got7fsn_ti														biological_process											owl:Class	
GO:1902507	biolink:NamedThing	thiazole synthase complex	A protein complex which is capable of thiazole synthase activity.	got7fsn_ti							bhm	2013-11-14T16:19:28Z						cellular_component											owl:Class	
NCBITaxon:451864	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000308	biolink:NamedThing	cytoplasmic cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm.	got7fsn_ti	CDK holoenzyme													cellular_component											owl:Class	
CL:0000733	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032563	biolink:NamedThing	dADP binding	Binding to dADP, deoxyadenosine diphosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0051773	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071637	biolink:NamedThing	regulation of monocyte chemotactic protein-1 production	Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1.	got7fsn_ti	regulation of CCL2 production|regulation of MCP-1 production						mah	2010-02-12T10:39:51Z						biological_process											owl:Class	
GO:1902065	biolink:NamedThing	response to L-glutamate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.	got7fsn_ti							tb	2013-04-16T21:21:14Z						biological_process											owl:Class	
GO:0005761	biolink:NamedThing	mitochondrial ribosome	A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.	got7fsn_ti	55S ribosome, mitochondrial													cellular_component											owl:Class	
GO:0097033	biolink:NamedThing	obsolete mitochondrial respiratory chain complex III biogenesis	OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex III (also known as cytochrome bc(1) complex or ubiquinol-cytochrome c reductase), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	got7fsn_ti	mitochondrial cytochrome bc(1) complex biogenesis	https://github.com/geneontology/go-ontology/issues/15173			The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		pr	2011-04-05T03:00:31Z		True				biological_process											owl:Class	
UBERON:0002331	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002233	biolink:NamedThing	leukocyte chemotaxis involved in immune response	The movement of an immune cell in response to an external stimulus a part of an immune response.	got7fsn_ti	immune cell chemotaxis during immune response|leucocyte chemotaxis during immune response													biological_process											owl:Class	
GO:0016123	biolink:NamedThing	xanthophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.	got7fsn_ti	xanthophyll synthesis|xanthophyll formation|xanthophyll anabolism|xanthophyll biosynthesis													biological_process											owl:Class	
GO:0061084	biolink:NamedThing	negative regulation of protein refolding	Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.	got7fsn_ti							dph	2010-04-26T01:11:29Z						biological_process											owl:Class	
GO:0008280	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902646	biolink:NamedThing	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.	got7fsn_ti	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis						di	2014-01-21T17:57:57Z						biological_process											owl:Class	
GO:0052644	biolink:NamedThing	chlorophyllide a metabolic process	The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a.	got7fsn_ti	chlorophyllide a metabolism													biological_process											owl:Class	
GO:0045343	biolink:NamedThing	regulation of MHC class I biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.	got7fsn_ti	regulation of MHC class I biosynthesis|regulation of MHC class I formation|regulation of major histocompatibility complex class I biosynthetic process|regulation of MHC class I anabolism|regulation of MHC class I synthesis|regulation of major histocompatibility complex class I biosynthesis													biological_process											owl:Class	
GO:0010775	biolink:NamedThing	meiotic strand invasion involved in meiotic gene conversion	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.	got7fsn_ti														biological_process											owl:Class	
GO:0001584	biolink:NamedThing	obsolete rhodopsin-like receptor activity	OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the rhodopsin receptor.	got7fsn_ti	Class A GPCR|Class A G protein coupled receptor|class A orphan receptor activity|rhodopsin-like receptor activity|Class A G-protein coupled receptor				This term was made obsolete because it represents a gene product and is named based on protein features.					True	GO:0001620			molecular_function											owl:Class	
CHEBI:64518	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060964	biolink:NamedThing	regulation of gene silencing by miRNA	Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: RNA (often mRNA) cleavage or mRNA translational repression.	got7fsn_ti	regulation of gene silencing by microRNA						dph	2009-10-05T03:10:28Z						biological_process											owl:Class	
GO:2000245	biolink:NamedThing	negative regulation of FtsZ-dependent cytokinesis	Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis.	got7fsn_ti	negative regulation of prokaryotic fission|negative regulation of prokaryote-type cytokinesis						mah	2010-11-10T02:46:39Z						biological_process											owl:Class	
CHEBI:28428	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090181	biolink:NamedThing	regulation of cholesterol metabolic process	Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti							tb	2009-12-18T10:33:49Z						biological_process											owl:Class	
GO:0042191	biolink:NamedThing	methylmercury metabolic process	The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species.	got7fsn_ti	methylmercury metabolism													biological_process											owl:Class	
GO:0046714	biolink:NamedThing	borate binding	Binding to borate, the anion (BO3)3-.	got7fsn_ti	boron binding													molecular_function											owl:Class	
GO:1901423	biolink:NamedThing	response to benzene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus.	got7fsn_ti							tt	2012-10-01T18:35:11Z						biological_process											owl:Class	
GO:0030385	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PO:0000431	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:73702	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061169	biolink:NamedThing	positive regulation of hair placode formation	Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.	got7fsn_ti							dph	2010-06-25T01:08:50Z						biological_process											owl:Class	
GO:1905174	biolink:NamedThing	regulation of vascular associated smooth muscle cell dedifferentiation	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.	got7fsn_ti	regulation of vascular smooth muscle cell dedifferentiation						rph	2016-05-03T12:31:57Z						biological_process											owl:Class	
CL:0000819	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903631	biolink:NamedThing	negative regulation of aminoacyl-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of aminoacyl-tRNA ligase activity.	got7fsn_ti	down-regulation of aminoacyl-tRNA ligase activity|down regulation of aminoacyl-tRNA synthetase auxiliary protein activity|down-regulation of aminoacyl-tRNA synthetase auxiliary protein activity|downregulation of aminoacyl-tRNA synthetase auxiliary protein activity|negative regulation of aminoacyl-tRNA synthetase auxiliary protein activity|inhibition of aminoacyl-tRNA ligase activity|inhibition of aminoacyl-tRNA synthetase auxiliary protein activity|down-regulation of aminoacyl-tRNA synthetase activity|downregulation of aminoacyl-tRNA synthetase activity|down regulation of aminoacyl-tRNA synthetase activity|inhibition of aminoacyl-tRNA synthetase activity|negative regulation of aminoacyl-tRNA synthetase activity|downregulation of aminoacyl-tRNA ligase activity|down regulation of aminoacyl-tRNA ligase activity						sl	2014-11-20T00:22:12Z						biological_process											owl:Class	
GO:1900554	biolink:NamedThing	asperfuranone biosynthetic process	The chemical reactions and pathways resulting in the formation of asperfuranone.	got7fsn_ti	asperfuranone formation|asperfuranone synthesis|asperfuranone biosynthesis|asperfuranone anabolism						di	2012-05-15T01:31:58Z						biological_process											owl:Class	
GO:0019791	biolink:NamedThing	obsolete FAT10 hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	FAT10 hydrolase activity				This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True				molecular_function											owl:Class	
GO:0090156	biolink:NamedThing	cellular sphingolipid homeostasis	Any biological process involved in the maintenance of an internal steady state of sphingolipids at the level of the cell.	got7fsn_ti							tb	2009-12-08T08:21:36Z						biological_process											owl:Class	
GO:0070283	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0120027	biolink:NamedThing	regulation of osmosensory signaling pathway	Any process that modulates the frequency, rate or extent of osmosensory signaling pathway.	got7fsn_ti							krc	2017-03-31T14:45:01Z						biological_process											owl:Class	
GO:0017094	biolink:NamedThing	obsolete sterol regulatory element-binding protein site 1 protease activity	OBSOLETE. Catalysis of the cleavage of a Leu-Ser bond within the luminal loop of a sterol regulatory element binding protein (SREBP). This activity is the first of two sequential cleavage reactions and cleaves SREBP into two membrane-bound halves.	got7fsn_ti	SREBP site 1 protease activity|sterol regulatory element-binding protein site 1 protease activity			GO:0008236	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:2000226	biolink:NamedThing	regulation of pancreatic A cell differentiation	Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation.	got7fsn_ti	regulation of pancreatic alpha cell differentiation						mah	2010-11-09T03:43:37Z						biological_process											owl:Class	
GO:2001207	biolink:NamedThing	regulation of transcription elongation from RNA polymerase I promoter	Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.	got7fsn_ti	regulation of RNA elongation from Pol I promoter						se	2011-11-11T10:46:28Z						biological_process											owl:Class	
GO:0051333	biolink:NamedThing	meiotic nuclear membrane reassembly	The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs.	got7fsn_ti	meiotic nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636												biological_process											owl:Class	
GO:0017122	biolink:NamedThing	protein N-acetylglucosaminyltransferase complex	A protein complex capable of protein N-acetylglucosaminyltransferase activity, the addition of nucleotide-activated sugars onto the polypeptide according to reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. The complex has different compositions in different species: In mammals it is often a homotrimer, in bacteria a heterotetramer of 2 different subunits.	got7fsn_ti	O-GlcNAc transferase complex|UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase	https://github.com/geneontology/go-ontology/issues/16994												cellular_component											owl:Class	
GO:0052431	biolink:NamedThing	obsolete modulation by organism of symbiont T-cell mediated immune response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of a symbiont organism, where the two organisms are in a symbiotic interaction. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont T-cell mediated immune response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0035594	biolink:NamedThing	ganglioside binding	Binding to a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.	got7fsn_ti							bf	2010-11-11T02:11:38Z						molecular_function											owl:Class	
GO:0034183	biolink:NamedThing	negative regulation of maintenance of mitotic sister chromatid cohesion	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.	got7fsn_ti														biological_process											owl:Class	
GO:0014073	biolink:NamedThing	response to tropane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.	got7fsn_ti														biological_process											owl:Class	
GO:0042253	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001092	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046880	biolink:NamedThing	regulation of follicle-stimulating hormone secretion	Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.	got7fsn_ti	regulation of FSH secretion|regulation of follicle stimulating hormone secretion													biological_process											owl:Class	
OBO:GOCHE_64909	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0086079	biolink:NamedThing	gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	got7fsn_ti							dph	2011-11-22T10:36:23Z						molecular_function											owl:Class	
CHEBI:46342	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034151	biolink:NamedThing	regulation of toll-like receptor 6 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.	got7fsn_ti	regulation of TLR6 signaling pathway|regulation of toll-like receptor 6 signalling pathway													biological_process											owl:Class	
GO:0019990	biolink:NamedThing	pteridine catabolic process	The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.	got7fsn_ti	pteridine degradation|pteridine breakdown|pteridine catabolism													biological_process											owl:Class	
CHEBI:10119	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902890	biolink:NamedThing	regulation of root hair elongation	Any process that modulates the frequency, rate or extent of root hair elongation.	got7fsn_ti							als	2014-04-07T13:46:40Z						biological_process											owl:Class	
GO:0006460	biolink:NamedThing	obsolete peptidyl-prolyl isomerase B reaction	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	peptidyl-prolyl isomerase B reaction				This term was made obsolete because it represents a molecular function and not a biological process.	GO:0003755				True				biological_process											owl:Class	
GO:1905412	biolink:NamedThing	negative regulation of mitotic cohesin loading	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading.	got7fsn_ti							vw	2016-08-27T15:24:35Z						biological_process											owl:Class	
CHEBI:28767	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031155	biolink:NamedThing	regulation of reproductive fruiting body development	Any process that modulates the frequency, rate or extent of reproductive fruiting body development.	got7fsn_ti	regulation of fruiting body formation													biological_process											owl:Class	
GO:0035862	biolink:NamedThing	dITP metabolic process	The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.	got7fsn_ti	deoxyinosine 5'-triphosphate metabolic process|dITP metabolism|2'-Deoxyinosine-5'-triphosphate metabolic process|deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) metabolic process|2'-Deoxyinosine 5'-triphosphate metabolic process						bf	2011-05-25T02:52:58Z						biological_process											owl:Class	
GO:0002660	biolink:NamedThing	positive regulation of peripheral tolerance induction	Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.	got7fsn_ti	upregulation of peripheral tolerance induction|up regulation of peripheral tolerance induction|activation of peripheral tolerance induction|up-regulation of peripheral tolerance induction|stimulation of peripheral tolerance induction													biological_process											owl:Class	
CHEBI:58074	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000985	biolink:NamedThing	positive regulation of ATP citrate synthase activity	Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity.	got7fsn_ti	positive regulation of citrate-ATP lyase activity|positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|positive regulation of ATP citrate (pro-S)-lyase activity|positive regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|positive regulation of citrate cleavage enzyme activity|positive regulation of ATP-citric lyase activity|positive regulation of ATP-citrate (pro-S)-lyase activity|positive regulation of ATP-citrate (pro-S-)-lyase activity|positive regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|positive regulation of adenosine triphosphate citrate lyase activity|positive regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|positive regulation of citric cleavage enzyme activity|positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity						vk	2011-08-04T03:15:31Z						biological_process											owl:Class	
CHEBI:142797	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010497	biolink:NamedThing	plasmodesmata-mediated intercellular transport	The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.	got7fsn_ti	single-organism plasmodesmata-mediated intercellular transport|plasmodesma-mediated intercellular transport|plasmodesma-mediated cell-to-cell transport|single organism plasmodesmata-mediated intercellular transport|plasmodesmata-mediated cell-to-cell transport						jl	2013-12-19T13:37:36Z			GO:1902587			biological_process											owl:Class	
GO:0046602	biolink:NamedThing	regulation of mitotic centrosome separation	Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis.	got7fsn_ti														biological_process											owl:Class	
GO:0046437	biolink:NamedThing	D-amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids.	got7fsn_ti	D-amino acid biosynthesis|D-amino acid anabolism|D-amino acid formation|D-amino acid synthesis													biological_process											owl:Class	
GO:0050997	biolink:NamedThing	quaternary ammonium group binding	Binding to a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.	got7fsn_ti	quaternary amine binding													molecular_function											owl:Class	
CHEBI:58527	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044037	biolink:NamedThing	obsolete multi-organism cell wall macromolecule metabolic process	OBSOLETE. The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	got7fsn_ti	multi-organism cell wall macromolecule metabolism	https://github.com/geneontology/go-ontology/issues/19769			This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:0019427	biolink:NamedThing	acetyl-CoA biosynthetic process from acetate	The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.	got7fsn_ti	acetyl-CoA synthesis from acetate|acetate utilization|acetyl-CoA anabolism from acetate|acetyl-CoA formation from acetate											MetaCyc:ACETATEUTIL-PWY		biological_process											owl:Class	
GO:0052255	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58149	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002723	biolink:NamedThing	positive regulation of B cell cytokine production	Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.	got7fsn_ti	up regulation of B cell cytokine production|positive regulation of B lymphocyte cytokine production|positive regulation of B-lymphocyte cytokine production|upregulation of B cell cytokine production|positive regulation of B-cell cytokine production|up-regulation of B cell cytokine production|activation of B cell cytokine production|stimulation of B cell cytokine production													biological_process											owl:Class	
GO:0050710	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031608	biolink:NamedThing	obsolete ER proteasome core complex, beta-subunit complex	OBSOLETE. The subunits forming the inner ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell.	got7fsn_ti					This term was made obsolete because there is no evidence in the literature of its existence.					True				cellular_component											owl:Class	
GO:0034125	biolink:NamedThing	negative regulation of MyD88-dependent toll-like receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.	got7fsn_ti	negative regulation of MyD88-dependent TLR signaling pathway|negative regulation of MyD88-dependent toll-like receptor signalling pathway													biological_process											owl:Class	
GO:0090108	biolink:NamedThing	positive regulation of high-density lipoprotein particle assembly	Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.	got7fsn_ti							tb	2009-11-25T10:50:18Z						biological_process											owl:Class	
UBERON:0003052	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0100063	biolink:NamedThing	obsolete regulation of dipeptide transmembrane transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates dipeptide transmembrane transport.	got7fsn_ti					The term was obsoleted because it is better represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:0015715	biolink:NamedThing	nucleotide-sulfate transport	The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	nucleotide-sulphate transport													biological_process											owl:Class	
GO:1905429	biolink:NamedThing	response to glycine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.	got7fsn_ti	response to glycin|response to aminoacetic acid|response to aminoethanoic acid|response to Gly						sl	2016-09-08T22:09:15Z						biological_process											owl:Class	
CHEBI:15942	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24402	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64506	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034036	biolink:NamedThing	purine ribonucleoside bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	purine ribonucleoside bisphosphate synthesis|purine ribonucleoside bisphosphate biosynthesis|purine ribonucleoside bisphosphate formation|purine ribonucleoside bisphosphate anabolism													biological_process											owl:Class	
GO:0010891	biolink:NamedThing	negative regulation of sequestering of triglyceride	Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.	got7fsn_ti	negative regulation of triglyceride sequestration|negative regulation of sequestering of triacylglycerol													biological_process											owl:Class	
GO:0140329	biolink:NamedThing	lysophospholipid translocation	The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.	got7fsn_ti							pg	2019-05-03T07:26:52Z						biological_process											owl:Class	
CHEBI:27547	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072731	biolink:NamedThing	cellular response to papulacandin B	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.	got7fsn_ti							mah	2012-05-31T11:30:39Z						biological_process											owl:Class	
GO:0060689	biolink:NamedThing	cell differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.	got7fsn_ti							dph	2009-06-08T01:01:35Z						biological_process											owl:Class	
GO:0060687	biolink:NamedThing	regulation of branching involved in prostate gland morphogenesis	Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.	got7fsn_ti							dph	2009-06-05T12:37:14Z						biological_process											owl:Class	
GO:0052281	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902053	biolink:NamedThing	regulation of neosartoricin biosynthetic process	Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process.	got7fsn_ti	regulation of neosartoricin synthesis|regulation of neosartoricin anabolism|regulation of neosartoricin biosynthesis|regulation of neosartoricin formation						di	2013-04-11T15:46:06Z						biological_process											owl:Class	
CHEBI:36615	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044701	biolink:NamedThing	obsolete response to stimulus by single organism	OBSOLETE. A response to a stimulus that involves only one organism.	got7fsn_ti	response to stimulus by single organism				This term was made obsolete because we decided that all responses are single-organism.		jl	2012-09-19T15:40:57Z		True				biological_process											owl:Class	
GO:0019402	biolink:NamedThing	galactitol metabolic process	The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	got7fsn_ti	galactitol metabolism													biological_process											owl:Class	
GO:0003132	biolink:NamedThing	mesodermal-endodermal cell signaling involved in heart induction	Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction.	got7fsn_ti	mesodermal-endodermal cell signalling involved in heart induction						tb	2009-09-22T03:08:52Z						biological_process											owl:Class	
GO:0070328	biolink:NamedThing	triglyceride homeostasis	Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.	got7fsn_ti	triacylglycerol homeostasis													biological_process											owl:Class	
GO:0045045	biolink:NamedThing	obsolete secretory pathway	OBSOLETE. The pathway along which proteins and other substances are moved around and out of the cell. After synthesis on the ribosomes of the endoplasmic reticulum (ER), completed polypeptide chains are moved to the Golgi complex and subsequently sorted to various destinations. Proteins synthesized and sorted in the secretory pathway include not only those that are secreted from the cell but also enzymes and other resident proteins in the lumen of the ER, Golgi, and lysosomes as well as integral proteins in the membranes of these organelles and the plasma membrane.	got7fsn_ti	secretory pathway			GO:0032940	This term was made obsolete because it artificially groups a number of other terms, leading to path problems, its definition is unclear (and lacks genus-differentia features), and it has probably been used incorrectly in annotations.					True				biological_process											owl:Class	
GO:0062124	biolink:NamedThing	4-hydroxybutyrate receptor activity	Combining with 4-hydroxybutyrte to initiate a change in cell activity.	got7fsn_ti	gamma-hydroxybutyrate receptor activity						dph	2019-05-15T12:22:38Z						molecular_function											owl:Class	
GO:1905585	biolink:NamedThing	regulation of outer hair cell apoptotic process	Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process.	got7fsn_ti	regulation of cochlear outer hair cell apoptotic process|regulation of outer hair cell apoptosis|regulation of cochlear outer hair cell apoptosis						sl	2016-10-24T22:35:34Z						biological_process											owl:Class	
GO:0100033	biolink:NamedThing	obsolete regulation of fungal-type cell wall biogenesis by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fungal-type cell wall biogenesis.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
GO:2001093	biolink:NamedThing	galactotriose transport	The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:01:29Z						biological_process											owl:Class	
GO:0008181	biolink:NamedThing	obsolete tumor suppressor	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	tumor suppressor				This term was made obsolete because it does not represent a true biological function, rather a pathology that occurs when a particular gene product is inactivated in some way.	GO:0051726				True				molecular_function											owl:Class	
GO:0016144	biolink:NamedThing	S-glycoside biosynthetic process	The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.	got7fsn_ti	S-glycoside formation|S-glycoside biosynthesis|thioglycoside biosynthesis|thioglycoside biosynthetic process|S-glycoside synthesis|S-glycoside anabolism													biological_process											owl:Class	
GO:0000767	biolink:NamedThing	cell morphogenesis involved in conjugation	The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types.	got7fsn_ti														biological_process											owl:Class	
UBERON:0004139	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000036	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046111	biolink:NamedThing	xanthine biosynthetic process	The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.	got7fsn_ti	xanthine formation|xanthine synthesis|xanthine biosynthesis|xanthine anabolism													biological_process											owl:Class	
UBERON:0004906	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006065	biolink:NamedThing	UDP-glucuronate biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-glucuronate formation|UDP-glucuronate biosynthesis|UDP-glucuronate synthesis|UDP-glucuronate anabolism											MetaCyc:PWY-4841		biological_process											owl:Class	
CHEBI:28017	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0036520	biolink:NamedThing	astrocyte-dopaminergic neuron signaling	Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron.	got7fsn_ti	midbrain dopaminergic neuron-astrocyte crosstalk|astrocyte-dopaminergic neuron cell signaling|mesencephalic dopaminergic neuron-astrocyte crosstalk|dopaminergic neuron-astrocyte crosstalk						bf	2016-02-29T14:05:47Z						biological_process											owl:Class	
GO:2000388	biolink:NamedThing	positive regulation of antral ovarian follicle growth	Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.	got7fsn_ti							yaf	2011-02-16T04:54:01Z						biological_process											owl:Class	
CL:1000222	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0040015	biolink:NamedThing	negative regulation of multicellular organism growth	Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.	got7fsn_ti	negative regulation of body size|negative regulation of body growth													biological_process											owl:Class	
GO:0010811	biolink:NamedThing	positive regulation of cell-substrate adhesion	Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.	got7fsn_ti														biological_process											owl:Class	
GO:0015535	biolink:NamedThing	fucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in).	got7fsn_ti	fucose:hydrogen symporter activity											RHEA:29023		molecular_function											owl:Class	
GO:1902194	biolink:NamedThing	2-methylbut-2-enoyl-CoA(4-) biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-).	got7fsn_ti	2-methylbut-2-enoyl-CoA(4-) biosynthesis|2-methylbut-2-enoyl-CoA(4-) synthesis|2-methylbut-2-enoyl-CoA(4-) anabolism|2-methylbut-2-enoyl-CoA(4-) formation						ms	2013-06-06T09:40:46Z						biological_process											owl:Class	
GO:0042399	biolink:NamedThing	ectoine metabolic process	The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.	got7fsn_ti	ectoine metabolism													biological_process											owl:Class	
CHEBI:37690	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61555	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035441	biolink:NamedThing	cell migration involved in vasculogenesis	The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.	got7fsn_ti							bf	2010-04-09T03:53:01Z						biological_process											owl:Class	
GO:1901772	biolink:NamedThing	lincomycin metabolic process	The chemical reactions and pathways involving lincomycin.	got7fsn_ti	lincomycin metabolism						yaf	2013-01-15T11:53:52Z						biological_process											owl:Class	
GO:0070389	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900953	biolink:NamedThing	regulation of 18-methylnonadec-1-ene metabolic process	Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.	got7fsn_ti	regulation of 18-methylnonadec-1-ene metabolism						tt	2012-06-14T03:25:16Z						biological_process											owl:Class	
GO:0033859	biolink:NamedThing	furaldehyde metabolic process	The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.	got7fsn_ti														biological_process											owl:Class	
GO:0070215	biolink:NamedThing	obsolete MDM2 binding	OBSOLETE. Binding to an isoform of the MDM2 protein, a negative regulator of p53.	got7fsn_ti	MDM2 binding			GO:0097371	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:0062025	biolink:NamedThing	regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.	got7fsn_ti							dph	2018-04-16T13:54:43Z						biological_process											owl:Class	
GO:0031541	biolink:NamedThing	negative regulation of anthocyanin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.	got7fsn_ti	negative regulation of anthocyanin anabolism|negative regulation of anthocyanin synthesis|downregulation of anthocyanin biosynthetic process|down-regulation of anthocyanin biosynthetic process|inhibition of anthocyanin biosynthetic process|negative regulation of anthocyanin biosynthesis|down regulation of anthocyanin biosynthetic process|negative regulation of anthocyanin formation													biological_process											owl:Class	
GO:1901681	biolink:NamedThing	sulfur compound binding	Binding to a sulfur compound.	got7fsn_ti	sulfur molecular entity binding						pr	2012-11-26T20:45:23Z						molecular_function											owl:Class	
GO:0016858	biolink:NamedThing	obsolete racemase and epimerase activity, acting on other compounds	OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives.	got7fsn_ti	racemase and epimerase activity, acting on other compounds				This term was made obsolete because it was an unnecessary grouping term.	GO:0016854				True				molecular_function											owl:Class	
GO:0098807	biolink:NamedThing	chloroplast thylakoid membrane protein complex	A protein complex that is part of a chloroplast thylakoid membrane.	got7fsn_ti														cellular_component											owl:Class	
CHEBI:58045	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090264	biolink:NamedThing	regulation of immune complex clearance by monocytes and macrophages	Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.	got7fsn_ti							tb	2010-02-04T04:31:29Z						biological_process											owl:Class	
GO:0052120	biolink:NamedThing	obsolete positive aerotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive aerotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
UBERON:0007375	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903335	biolink:NamedThing	regulation of vacuolar transport	Any process that modulates the frequency, rate or extent of vacuolar transport.	got7fsn_ti							vw	2014-08-18T13:16:04Z						biological_process											owl:Class	
GO:0048077	biolink:NamedThing	negative regulation of compound eye pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.	got7fsn_ti	down-regulation of eye pigmentation|downregulation of eye pigmentation|inhibition of eye pigmentation|negative regulation of eye pigmentation|down regulation of eye pigmentation													biological_process											owl:Class	
GO:0051573	biolink:NamedThing	negative regulation of histone H3-K9 methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.	got7fsn_ti	down-regulation of histone H3-K9 methylation|down regulation of histone H3-K9 methylation|inhibition of histone H3-K9 methylation|downregulation of histone H3-K9 methylation													biological_process											owl:Class	
UBERON:0002135	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904880	biolink:NamedThing	response to hydrogen sulfide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.	got7fsn_ti	response to sulfane|response to dihydridosulfur						sl	2016-01-04T23:56:27Z						biological_process											owl:Class	
GO:0120023	biolink:NamedThing	somatostatin binding	Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/13143					krc	2017-03-17T14:54:21Z						molecular_function											owl:Class	
GO:0048296	biolink:NamedThing	regulation of isotype switching to IgA isotypes	Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.	got7fsn_ti	regulation of class switching to IgA isotypes|regulation of class switch recombination to IgA isotypes|regulation of isotype switch recombination to IgA isotypes													biological_process											owl:Class	
GO:0035025	biolink:NamedThing	positive regulation of Rho protein signal transduction	Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.	got7fsn_ti	upregulation of Rho protein signal transduction|stimulation of Rho protein signal transduction|activation of Rho protein signal transduction|up regulation of Rho protein signal transduction|up-regulation of Rho protein signal transduction													biological_process											owl:Class	
GO:1900141	biolink:NamedThing	regulation of oligodendrocyte apoptotic process	Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process.	got7fsn_ti	regulation of oligodendrocyte apoptosis						yaf	2012-03-06T10:22:45Z						biological_process											owl:Class	
GO:0030264	biolink:NamedThing	nuclear fragmentation involved in apoptotic nuclear change	The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.	got7fsn_ti	nucleus fragmentation|apoptotic nuclear fragmentation|nuclear fragmentation during apoptosis													biological_process											owl:Class	
CHEBI:30616	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003918	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034201	biolink:NamedThing	response to oleic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.	got7fsn_ti	response to oleate													biological_process											owl:Class	
GO:1905143	biolink:NamedThing	eukaryotic translation initiation factor 2 complex assembly	The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex.	got7fsn_ti	eIF2 formation|eIF-2 formation|eukaryotic translation initiation factor 2 complex formation|eIF-2 assembly|eIF2 assembly						dph	2016-04-14T00:25:51Z						biological_process											owl:Class	
GO:0019354	biolink:NamedThing	siroheme biosynthetic process	The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.	got7fsn_ti	sirohaem biosynthesis|siroheme formation|siroheme anabolism|siroheme synthase activity|sirohaem biosynthetic process|siroheme synthesis|siroheme biosynthesis											MetaCyc:PWY-5194		biological_process											owl:Class	
GO:0003339	biolink:NamedThing	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.	got7fsn_ti							dph	2009-11-24T09:43:04Z						biological_process											owl:Class	
GO:0051188	biolink:NamedThing	obsolete cofactor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein.	got7fsn_ti	cofactor formation|cofactor biosynthesis|cofactor anabolism|cofactor synthesis				1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True				biological_process											owl:Class	
GO:0071671	biolink:NamedThing	regulation of smooth muscle cell chemotaxis	Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis.	got7fsn_ti							mah	2010-02-16T01:42:03Z						biological_process											owl:Class	
GO:1903354	biolink:NamedThing	regulation of distal tip cell migration	Any process that modulates the frequency, rate or extent of distal tip cell migration.	got7fsn_ti							pr	2014-08-21T10:05:08Z						biological_process											owl:Class	
GO:0110075	biolink:NamedThing	regulation of ferroptosis	Any process that modulates the frequency, rate or extent of ferroptosis.	got7fsn_ti							kmv	2018-01-11T17:51:48Z						biological_process											owl:Class	
CHEBI:16452	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005752	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0110032	biolink:NamedThing	positive regulation of G2/MI transition of meiotic cell cycle	Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.	got7fsn_ti							kmv	2017-07-12T20:40:54Z						biological_process											owl:Class	
GO:0010933	biolink:NamedThing	positive regulation of macrophage tolerance induction	Any process that increases the frequency, rate, or extent of B cell tolerance induction.	got7fsn_ti														biological_process											owl:Class	
GO:1900207	biolink:NamedThing	negative regulation of pronephric nephron tubule development	Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development.	got7fsn_ti	inhibition of pronephric nephron tubule development|down regulation of pronephric nephron tubule development|downregulation of pronephric nephron tubule development|down-regulation of pronephric nephron tubule development						bf	2012-03-22T09:23:23Z						biological_process											owl:Class	
PO:0025195	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002685	biolink:NamedThing	regulation of leukocyte migration	Any process that modulates the frequency, rate, or extent of leukocyte migration.	got7fsn_ti	regulation of leucocyte migration|regulation of immune cell migration													biological_process											owl:Class	
GO:0000203	biolink:NamedThing	obsolete activation of MAPKKK during sporulation (sensu Saccharomyces)	OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	got7fsn_ti	activation of MAPKKK during sporulation (sensu Saccharomyces)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
CHEBI:60523	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043594	biolink:NamedThing	outer endospore membrane	The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat.	got7fsn_ti														cellular_component											owl:Class	
GO:0120188	biolink:NamedThing	regulation of bile acid secretion	Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.	got7fsn_ti							krc	2018-07-16T22:28:58Z						biological_process											owl:Class	
CHEBI:28247	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001190	biolink:NamedThing	obsolete transcriptional activator activity, RNA polymerase II transcription factor binding	OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	got7fsn_ti	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding transcription activator activity	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0001228|GO:0061629	krc	2011-08-25T02:07:14Z		True				molecular_function											owl:Class	
CHEBI:24505	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000514	biolink:NamedThing	regulation of CD4-positive, alpha-beta T cell activation	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.	got7fsn_ti							ebc	2011-03-22T10:36:56Z						biological_process											owl:Class	
GO:1900832	biolink:NamedThing	D-leucine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-leucine.	got7fsn_ti	D-leucine degradation|D-leucine catabolism|D-leucine breakdown						se	2012-06-06T09:37:40Z						biological_process											owl:Class	
CHEBI:64607	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57836	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000232	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58307	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045097	biolink:NamedThing	obsolete basic/neutral keratin	OBSOLETE. A type of intermediate filament.	got7fsn_ti	type II intermediate filament|basic/neutral keratin			GO:0045095	This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
GO:0071543	biolink:NamedThing	diphosphoinositol polyphosphate metabolic process	The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.	got7fsn_ti	diphosphoinositol polyphosphate metabolism						mah	2010-01-12T05:04:00Z						biological_process											owl:Class	
UBERON:0010210	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901331	biolink:NamedThing	positive regulation of odontoblast differentiation	Any process that activates or increases the frequency, rate or extent of odontoblast differentiation.	got7fsn_ti	up regulation of odontoblast differentiation|activation of odontoblast differentiation|up-regulation of odontoblast differentiation|upregulation of odontoblast differentiation						hjd	2012-08-31T16:50:35Z						biological_process											owl:Class	
CL:0008012	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901242	biolink:NamedThing	ABC-type doxorubicin transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out).	got7fsn_ti	doxorubicin transmembrane-transporting ATPase activity|ATPase-coupled doxorubicin transmembrane transporter activity						jl	2012-08-07T15:10:13Z				TC:3.A.1.105.1		molecular_function											owl:Class	
GO:1905752	biolink:NamedThing	regulation of argininosuccinate synthase activity	Any process that modulates the frequency, rate or extent of argininosuccinate synthase activity.	got7fsn_ti	regulation of L-citrulline:L-aspartate ligase (AMP-forming)|regulation of arginosuccinate synthetase activity|regulation of argininosuccinic acid synthetase activity|regulation of citrulline--aspartate ligase activity|regulation of argininosuccinate synthetase activity|regulation of arginine succinate synthetase activity						dos	2016-12-12T11:43:52Z						biological_process											owl:Class	
GO:0106137	biolink:NamedThing	IkappaB kinase complex binding	Binding to a IkappaB kinase complex.	got7fsn_ti							hjd	2018-08-15T14:05:10Z						molecular_function											owl:Class	
CHEBI:62974	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0021864	biolink:NamedThing	obsolete radial glial cell division in forebrain	OBSOLETE. The mitotic division of radial glial cells in the developing forebrain.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.					True				biological_process											owl:Class	
GO:0044139	biolink:NamedThing	obsolete modulation of growth of symbiont on or near host	OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass on or near the cells or tissues of the host organism.	got7fsn_ti					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T04:24:59Z		True				biological_process											owl:Class	
GO:0061018	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905100	biolink:NamedThing	regulation of apoptosome assembly	Any process that modulates the frequency, rate or extent of apoptosome assembly.	got7fsn_ti	regulation of apoptosome formation						bc	2016-04-04T08:57:42Z						biological_process											owl:Class	
GO:0061192	biolink:NamedThing	negative regulation of vacuole fusion, non-autophagic	Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.	got7fsn_ti							dph	2010-07-14T09:35:18Z						biological_process											owl:Class	
GO:2000468	biolink:NamedThing	regulation of peroxidase activity	Any process that modulates the frequency, rate or extent of peroxidase activity.	got7fsn_ti	regulation of donor:hydrogen-peroxide oxidoreductase activity|regulation of oxyperoxidase activity|regulation of peroxidase reaction						bf	2011-03-08T02:18:18Z						biological_process											owl:Class	
GO:1904396	biolink:NamedThing	regulation of neuromuscular junction development	Any process that modulates the frequency, rate or extent of neuromuscular junction development.	got7fsn_ti	regulation of neuromuscular junction stability|regulation of NMJ stability|regulation of neuromuscular junction organization						sl	2015-06-23T19:23:42Z						biological_process											owl:Class	
GO:0010602	biolink:NamedThing	regulation of 1-aminocyclopropane-1-carboxylate metabolic process	Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.	got7fsn_ti														biological_process											owl:Class	
GO:0046493	biolink:NamedThing	lipid A metabolic process	The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.	got7fsn_ti	lipid A metabolism													biological_process											owl:Class	
CHEBI:38206	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032559	biolink:NamedThing	adenyl ribonucleotide binding	Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	got7fsn_ti														molecular_function											owl:Class	
UBERON:0001912	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001954	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060386	biolink:NamedThing	synapse assembly involved in innervation	The assembly of a synapse within a target tissue in which a nerve is invading.	got7fsn_ti	synapse biogenesis involved in innervation|synaptogenesis involved in innervation													biological_process											owl:Class	
GO:0032007	biolink:NamedThing	negative regulation of TOR signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.	got7fsn_ti	negative regulation of TOR signalling pathway|down regulation of TOR signaling pathway|down-regulation of TOR signaling pathway|inhibition of TOR signaling pathway|negative regulation of TOR signaling cascade|negative regulation of target of rapamycin signaling pathway|downregulation of TOR signaling pathway|negative regulation of target of rapamycin signalling pathway|negative regulation of TOR signaling pathway													biological_process											owl:Class	
GO:0019001	biolink:NamedThing	guanyl nucleotide binding	Binding to a guanyl nucleotide, consisting of guanosine esterified with (ortho)phosphate.	got7fsn_ti												Reactome:R-HSA-156909		molecular_function											owl:Class	
GO:0010935	biolink:NamedThing	regulation of macrophage cytokine production	Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti														biological_process											owl:Class	
GO:0010393	biolink:NamedThing	galacturonan metabolic process	The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues.	got7fsn_ti	galacturonan metabolism													biological_process											owl:Class	
GO:2000939	biolink:NamedThing	regulation of plant-type cell wall cellulose catabolic process	Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process.	got7fsn_ti	regulation of plant-type cell wall polysaccharide breakdown						tt	2011-08-01T02:07:11Z						biological_process											owl:Class	
GO:2000633	biolink:NamedThing	positive regulation of pre-miRNA processing	Any process that activates or increases the frequency, rate or extent of pre-microRNA processing.	got7fsn_ti	positive regulation of pre-microRNA processing						dph	2011-04-18T03:50:22Z						biological_process											owl:Class	
CHEBI:59062	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903649	biolink:NamedThing	regulation of cytoplasmic transport	Any process that modulates the frequency, rate or extent of cytoplasmic transport.	got7fsn_ti	regulation of cytoplasmic streaming						jl	2014-11-24T13:38:17Z						biological_process											owl:Class	
GO:1901938	biolink:NamedThing	(-)-exo-alpha-bergamotene metabolic process	The chemical reactions and pathways involving (-)-exo-alpha-bergamotene.	got7fsn_ti	(-)-exo-alpha-bergamotene metabolism						ms	2013-02-18T14:55:23Z						biological_process											owl:Class	
GO:0071900	biolink:NamedThing	regulation of protein serine/threonine kinase activity	Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.	got7fsn_ti							mah	2010-09-15T03:08:35Z						biological_process											owl:Class	
UBERON:0005404	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000256	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0022866	biolink:NamedThing	obsolete transmembrane 1-electron transfer carrier	OBSOLETE. Enables transfer of one electron across a membrane.	got7fsn_ti	transmembrane one-electron transfer carrier				The reason for obsoletion is that the term does not represent a molecular function but rather a process.					True				molecular_function											owl:Class	
GO:0052240	biolink:NamedThing	obsolete positive chemotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive chemotaxis within other organism during symbiotic interaction|positive chemotaxis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:1904306	biolink:NamedThing	positive regulation of gastro-intestinal system smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.	got7fsn_ti	up regulation of gastro-intestinal system smooth muscle contraction|up-regulation of gastro-intestinal system smooth muscle contraction|upregulation of gastro-intestinal system smooth muscle contraction|activation of gastro-intestinal system smooth muscle contraction						sl	2015-06-09T23:18:54Z						biological_process											owl:Class	
GO:0005711	biolink:NamedThing	obsolete meiotic chromosome	OBSOLETE. A chromosome involved in the process of meiosis.	got7fsn_ti	meiotic chromosome				This term was made obsolete because it is based on a process.	GO:0000794				True				cellular_component											owl:Class	
GO:1905130	biolink:NamedThing	carcinine import across plasma membrane	The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							dph	2016-04-12T15:15:18Z						biological_process											owl:Class	
GO:0099143	biolink:NamedThing	presynaptic actin cytoskeleton	The actin cytoskeleton that is part of a presynapse.	got7fsn_ti							dos	2017-06-09T18:36:19Z						cellular_component											owl:Class	
GO:0061237	biolink:NamedThing	convergent extension involved in mesonephric nephron morphogenesis	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros.	got7fsn_ti							dph	2010-08-19T03:02:44Z						biological_process											owl:Class	
GO:0046848	biolink:NamedThing	hydroxyapatite binding	Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin.	got7fsn_ti	hydroxylapatite binding													molecular_function											owl:Class	
GO:1903858	biolink:NamedThing	protein localization to old growing cell tip	A process in which a protein is transported to, or maintained in, a location within an old growing cell tip.	got7fsn_ti	protein localization in old growing cell tip|protein localisation in old growing cell tip|protein localisation to old growing cell tip						mah	2015-02-02T13:53:29Z						biological_process											owl:Class	
GO:0004393	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:28488	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27680	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005343	biolink:NamedThing	organic acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in).	got7fsn_ti	sodium:dicarboxylate/tricarboxylate symporter activity|sodium/chloride-dependent organic acid cotransporter activity											Reactome:R-HSA-8876312		molecular_function											owl:Class	
UBERON:0000120	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051774	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032741	biolink:NamedThing	positive regulation of interleukin-18 production	Any process that activates or increases the frequency, rate, or extent of interleukin-18 production.	got7fsn_ti	positive regulation of interleukin-18 secretion|up regulation of interleukin-18 production|positive regulation of interleukin-18 biosynthetic process|up-regulation of interleukin-18 production|positive regulation of IL-18 production|stimulation of interleukin-18 production|activation of interleukin-18 production|upregulation of interleukin-18 production										GO:0150122|GO:0045383			biological_process											owl:Class	
PO:0009046	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045828	biolink:NamedThing	positive regulation of isoprenoid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.	got7fsn_ti	positive regulation of isoprenoid metabolism|stimulation of isoprenoid metabolic process|upregulation of isoprenoid metabolic process|activation of isoprenoid metabolic process|up-regulation of isoprenoid metabolic process|up regulation of isoprenoid metabolic process													biological_process											owl:Class	
PR:000029394	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035506	biolink:NamedThing	negative regulation of myosin light chain kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity.	got7fsn_ti							bf	2010-04-30T10:49:21Z						biological_process											owl:Class	
GO:0030550	biolink:NamedThing	acetylcholine receptor inhibitor activity	Binds to and stops, prevents or reduces the activity of an acetylcholine receptor.	got7fsn_ti														molecular_function											owl:Class	
GO:0031302	biolink:NamedThing	intrinsic component of endosome membrane	The component of the endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to endosome membrane													cellular_component											owl:Class	
CHEBI:60941	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099617	biolink:NamedThing	matrix side of mitochondrial inner membrane	The side (leaflet) of the mitochondrial inner membrane that faces the matrix.	got7fsn_ti														cellular_component											owl:Class	
GO:0060399	biolink:NamedThing	positive regulation of growth hormone receptor signaling pathway	Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.	got7fsn_ti	positive regulation of growth hormone receptor signalling pathway													biological_process											owl:Class	
CHEBI:44811	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098922	biolink:NamedThing	extrinsic component of dense core granule membrane	The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:1901861	biolink:NamedThing	regulation of muscle tissue development	Any process that modulates the frequency, rate or extent of muscle tissue development.	got7fsn_ti							yaf	2013-02-01T10:30:47Z						biological_process											owl:Class	
GO:0050854	biolink:NamedThing	regulation of antigen receptor-mediated signaling pathway	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.	got7fsn_ti	regulation of antigen receptor mediated signalling pathway													biological_process											owl:Class	
GO:0035883	biolink:NamedThing	enteroendocrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.	got7fsn_ti							bf	2011-06-06T11:48:51Z						biological_process											owl:Class	
UBERON:0001818	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045633	biolink:NamedThing	positive regulation of mechanoreceptor differentiation	Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation.	got7fsn_ti	upregulation of mechanoreceptor differentiation|up-regulation of mechanoreceptor differentiation|up regulation of mechanoreceptor differentiation|activation of mechanoreceptor differentiation|stimulation of mechanoreceptor differentiation													biological_process											owl:Class	
GO:0010570	biolink:NamedThing	regulation of filamentous growth	Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.	got7fsn_ti														biological_process											owl:Class	
GO:2000686	biolink:NamedThing	obsolete regulation of rubidium ion transmembrane transporter activity	OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transmembrane transporter activity.	got7fsn_ti	regulation of rubidium cation transmembrane transporter activity|regulation of Rb+ transmembrane transporter activity|regulation of rubidium transmembrane transporter activity				This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-11T09:27:29Z		True				biological_process											owl:Class	
GO:0008536	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901078	biolink:NamedThing	negative regulation of relaxation of muscle	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle.	got7fsn_ti	downregulation of relaxation of muscle|inhibition of relaxation of muscle|down-regulation of relaxation of muscle|down regulation of relaxation of muscle						jl	2012-07-04T10:44:54Z						biological_process											owl:Class	
GO:0015839	biolink:NamedThing	cadaverine transport	The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0009171	biolink:NamedThing	purine deoxyribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	got7fsn_ti	purine deoxyribonucleoside monophosphate biosynthesis|purine deoxyribonucleoside monophosphate anabolism|purine deoxyribonucleoside monophosphate formation|purine deoxyribonucleoside monophosphate synthesis													biological_process											owl:Class	
GO:0005191	biolink:NamedThing	obsolete acidic epididymal glycoprotein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	acidic epididymal glycoprotein				This term was made obsolete because it describes modification and presence in body fluids rather than an activity.					True				molecular_function											owl:Class	
CHEBI:46024	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902390	biolink:NamedThing	regulation of N-terminal peptidyl-serine acetylation	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation.	got7fsn_ti							al	2013-09-11T14:46:45Z						biological_process											owl:Class	
GO:0031222	biolink:NamedThing	arabinan catabolic process	The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues.	got7fsn_ti	arabinan degradation|arabinan breakdown|arabinan catabolism													biological_process											owl:Class	
GO:0046161	biolink:NamedThing	heme a catabolic process	The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3.	got7fsn_ti	heme a catabolism|heme a breakdown|haem a catabolic process|heme a degradation|haem a catabolism													biological_process											owl:Class	
GO:0061965	biolink:NamedThing	positive regulation of entry into reproductive diapause	Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	got7fsn_ti							dph	2018-02-05T15:06:51Z						biological_process											owl:Class	
GO:0019693	biolink:NamedThing	ribose phosphate metabolic process	The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.	got7fsn_ti	ribose phosphate metabolism													biological_process											owl:Class	
GO:0009193	biolink:NamedThing	pyrimidine ribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine ribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0048326	biolink:NamedThing	positive regulation of axial mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination.	got7fsn_ti	stimulation of axial mesodermal cell fate determination|up-regulation of axial mesodermal cell fate determination|activation of axial mesodermal cell fate determination|up regulation of axial mesodermal cell fate determination|upregulation of axial mesodermal cell fate determination													biological_process											owl:Class	
GO:1901659	biolink:NamedThing	glycosyl compound biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosyl compound.	got7fsn_ti	glycosyl compound synthesis|glycosyl compound anabolism|glycosyl compound formation|glycosyl compound biosynthesis						pr	2012-11-20T14:24:19Z						biological_process											owl:Class	
GO:0035208	biolink:NamedThing	positive regulation of hemocyte proliferation	Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.	got7fsn_ti	up-regulation of hemocyte proliferation|stimulation of hemocyte proliferation|up regulation of hemocyte proliferation|upregulation of hemocyte proliferation|activation of hemocyte proliferation|positive regulation of arthropod blood cell proliferation													biological_process											owl:Class	
GO:2000448	biolink:NamedThing	positive regulation of macrophage migration inhibitory factor signaling pathway	Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.	got7fsn_ti	positive regulation of macrophage migration inhibitory factor signalling pathway|positive regulation of MIF signaling pathway						bf	2011-03-04T10:38:43Z						biological_process											owl:Class	
GO:0010682	biolink:NamedThing	obsolete cinnamic acid biosynthetic process involved in flavonoid metabolism	OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18200			This term was obsoleted because it does not represent a specific pathway.					True				biological_process											owl:Class	
UBERON:0001294	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060168	biolink:NamedThing	positive regulation of adenosine receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.	got7fsn_ti	positive regulation of adenosine receptor signalling pathway													biological_process											owl:Class	
GO:1903515	biolink:NamedThing	calcium ion transport from cytosol to endoplasmic reticulum	The directed movement of calcium ion from cytosol to endoplasmic reticulum.	got7fsn_ti							rl	2014-10-02T14:51:20Z						biological_process											owl:Class	
GO:2000053	biolink:NamedThing	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.	got7fsn_ti	regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification|regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification						jl	2010-08-20T01:13:28Z						biological_process											owl:Class	
GO:0006150	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052357	biolink:NamedThing	obsolete catabolism by host of symbiont cell wall pectin	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because there is no evidence it exists.					True				biological_process											owl:Class	
GO:0022865	biolink:NamedThing	obsolete transmembrane electron transfer carrier	OBSOLETE. Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics.	got7fsn_ti					The reason for obsoletion is that the term does not represent a molecular function but rather a process.					True		TC:5		molecular_function											owl:Class	
GO:1905648	biolink:NamedThing	regulation of shell calcification	Any process that modulates the frequency, rate or extent of shell calcification.	got7fsn_ti							pga	2016-11-08T16:24:36Z						biological_process											owl:Class	
GO:1904015	biolink:NamedThing	cellular response to serotonin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.	got7fsn_ti							sl	2015-03-06T19:34:00Z						biological_process											owl:Class	
GO:0033032	biolink:NamedThing	regulation of myeloid cell apoptotic process	Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process.	got7fsn_ti	regulation of myeloid cell apoptosis													biological_process											owl:Class	
GO:0010966	biolink:NamedThing	regulation of phosphate transport	Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							tb	2009-05-20T11:42:50Z						biological_process											owl:Class	
GO:1905769	biolink:NamedThing	positive regulation of double-stranded telomeric DNA binding	Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding.	got7fsn_ti	activation of double-stranded telomeric DNA binding|up-regulation of double-stranded telomeric DNA binding|up regulation of double-stranded telomeric DNA binding|upregulation of double-stranded telomeric DNA binding						nc	2016-12-20T15:34:15Z						biological_process											owl:Class	
GO:0099005	biolink:NamedThing	extrinsic component of postsynaptic recycling endosome membrane	The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti														cellular_component											owl:Class	
GO:0032162	biolink:NamedThing	mating projection septin band	A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection).	got7fsn_ti														cellular_component											owl:Class	
CHEBI:18407	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903713	biolink:NamedThing	asparagine transmembrane transport	The directed movement of asparagine across a membrane.	got7fsn_ti							vw	2014-12-06T08:17:55Z						biological_process											owl:Class	
GO:1903684	biolink:NamedThing	regulation of border follicle cell migration	Any process that modulates the frequency, rate or extent of border follicle cell migration.	got7fsn_ti	regulation of border cell migration						als	2014-12-01T13:35:39Z						biological_process											owl:Class	
GO:0110083	biolink:NamedThing	positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.	got7fsn_ti							kmv	2018-02-01T19:30:03Z						biological_process											owl:Class	
GO:0100050	biolink:NamedThing	obsolete negative regulation of mating type switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates mating type switching.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
PR:000028205	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060355	biolink:NamedThing	positive regulation of cell adhesion molecule production	Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.	got7fsn_ti														biological_process											owl:Class	
GO:0052536	biolink:NamedThing	obsolete positive regulation by organism of systemic acquired resistance in symbiont	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of systemic acquired resistance in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0140251	biolink:NamedThing	regulation protein catabolic process at presynapse	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.	got7fsn_ti		https://github.com/geneontology/synapse/issues/204			Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:35:39Z						biological_process											owl:Class	
CHEBI:26666	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900145	biolink:NamedThing	regulation of nodal signaling pathway involved in determination of left/right asymmetry	Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.	got7fsn_ti	regulation of nodal signalling pathway involved in determination of left/right asymmetry						bf	2012-03-06T11:00:32Z						biological_process											owl:Class	
GO:1901022	biolink:NamedThing	4-hydroxyphenylacetate metabolic process	The chemical reactions and pathways involving 4-hydroxyphenylacetate.	got7fsn_ti	4-hydroxyphenylacetate metabolism						yaf	2012-06-18T02:31:37Z						biological_process											owl:Class	
CHEBI:10003	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005120	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902869	biolink:NamedThing	regulation of amacrine cell differentiation	Any process that modulates the frequency, rate or extent of amacrine cell differentiation.	got7fsn_ti	regulation of amacrine neuron differentiation						mr	2014-04-03T15:24:35Z						biological_process											owl:Class	
GO:0003277	biolink:NamedThing	apoptotic process involved in endocardial cushion morphogenesis	Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	got7fsn_ti	apoptosis involved in endocardial cushion morphogenesis						dph	2009-10-20T09:37:03Z						biological_process											owl:Class	
GO:0004942	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0031300	biolink:NamedThing	intrinsic component of organelle membrane	The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to organelle membrane													cellular_component											owl:Class	
GO:2001094	biolink:NamedThing	xylotriose transport	The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:03:26Z						biological_process											owl:Class	
GO:0032107	biolink:NamedThing	regulation of response to nutrient levels	Any process that modulates the frequency, rate or extent of a response to nutrient levels.	got7fsn_ti														biological_process											owl:Class	
GO:0120226	biolink:NamedThing	succinyl-CoA binding	Binding to succinyl-CoA, an omega-carboxyacyl-CoA having succinoyl as the S-acyl component.	got7fsn_ti	succinyl-coenzyme A binding	https://github.com/geneontology/go-ontology/issues/19243					krc	2020-05-19T15:51:32Z						molecular_function											owl:Class	
GO:0036085	biolink:NamedThing	GDP-fucose import into Golgi lumen	The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-fucose transport across Golgi membrane|GDP-fucose transport into Golgi lumen|GDP-fucose import into Golgi						bf	2011-12-21T01:52:10Z						biological_process											owl:Class	
GO:2000742	biolink:NamedThing	regulation of anterior head development	Any process that modulates the frequency, rate or extent of anterior head development.	got7fsn_ti							yaf	2011-06-14T09:44:09Z						biological_process											owl:Class	
GO:0033253	biolink:NamedThing	regulation of penicillinase activity	Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative.	got7fsn_ti														biological_process											owl:Class	
GO:0006574	biolink:NamedThing	valine catabolic process	The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.	got7fsn_ti	valine catabolism|valine breakdown|valine degradation											MetaCyc:VALDEG-PWY		biological_process											owl:Class	
GO:1904551	biolink:NamedThing	cellular response to arachidonic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.	got7fsn_ti							sl	2015-08-13T20:53:31Z						biological_process											owl:Class	
GO:1904051	biolink:NamedThing	regulation of protein targeting to vacuole involved in autophagy	Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy.	got7fsn_ti					An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).		pad	2015-03-17T13:54:16Z						biological_process											owl:Class	
GO:1903066	biolink:NamedThing	regulation of protein localization to cell tip	Any process that modulates the frequency, rate or extent of protein localization to cell tip.	got7fsn_ti	regulation of protein localisation to cell tip						vw	2014-05-28T15:48:42Z						biological_process											owl:Class	
UBERON:0005326	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048044	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000655	biolink:NamedThing	negative regulation of cellular response to testosterone stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.	got7fsn_ti							vk	2011-05-02T03:23:59Z						biological_process											owl:Class	
CHEBI:32888	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001395	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904105	biolink:NamedThing	positive regulation of convergent extension involved in gastrulation	Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation.	got7fsn_ti	up-regulation of convergent extension involved in gastrulation|up regulation of convergent extension involved in gastrulation|upregulation of convergent extension involved in gastrulation|activation of convergent extension involved in gastrulation						dph	2015-04-01T11:17:18Z						biological_process											owl:Class	
GO:0099031	biolink:NamedThing	anchored component of postsynaptic density membrane	The component of the postsynaptic density membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
PR:000007806	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009710	biolink:NamedThing	tropane alkaloid biosynthetic process	The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.	got7fsn_ti	tropane alkaloid anabolism|tropane alkaloid formation|tropane alkaloid biosynthesis|tropane alkaloid synthesis													biological_process											owl:Class	
GO:1901972	biolink:NamedThing	positive regulation of DNA-5-methylcytosine glycosylase activity	Any process that activates or increases the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity.	got7fsn_ti	activation of DNA-5-methylcytosine glycosylase activity|up-regulation of DNA-5-methylcytosine glycosylase activity|upregulation of DNA-5-methylcytosine glycosylase activity|up regulation of DNA-5-methylcytosine glycosylase activity						tb	2013-02-25T20:01:34Z						biological_process											owl:Class	
GO:0052184	biolink:NamedThing	obsolete modulation by organism of symbiont hormone or growth regulator levels	OBSOLETE. The alteration by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont hormone or growth regulator levels				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:2000125	biolink:NamedThing	regulation of octopamine or tyramine signaling pathway	Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway.	got7fsn_ti	regulation of octopamine/tyramine signaling pathway|regulation of octopamine or tyramine signalling pathway						mah	2010-09-29T09:27:12Z						biological_process											owl:Class	
GO:1902007	biolink:NamedThing	regulation of toxin transport	Any process that modulates the frequency, rate or extent of toxin transport.	got7fsn_ti							dph	2013-03-22T12:53:56Z						biological_process											owl:Class	
GO:0036084	biolink:NamedThing	GDP-fucose import into endoplasmic reticulum lumen	The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-fucose import into endoplasmic reticulum|GDP-fucose transport into endoplasmic reticulum lumen|GDP-fucose transport across endoplasmic reticulum membrane						bf	2011-12-21T01:45:11Z						biological_process											owl:Class	
GO:0032670	biolink:NamedThing	regulation of interleukin-26 production	Any process that modulates the frequency, rate, or extent of interleukin-26 production.	got7fsn_ti	regulation of IL-26 production|regulation of interleukin-26 biosynthetic process										GO:0045530			biological_process											owl:Class	
CHEBI:37332	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070495	biolink:NamedThing	negative regulation of thrombin-activated receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.	got7fsn_ti	negative regulation of thrombin receptor signaling pathway|negative regulation of thrombin receptor signalling pathway													biological_process											owl:Class	
GO:0002604	biolink:NamedThing	regulation of dendritic cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:0045553	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000084	biolink:NamedThing	regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.	got7fsn_ti	regulation of mesonephric mesenchyme to epithelial transition						dph	2010-09-03T06:06:41Z						biological_process											owl:Class	
CHEBI:53183	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070807	biolink:NamedThing	positive regulation of phialide development	Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.	got7fsn_ti							mah	2009-07-08T04:48:08Z						biological_process											owl:Class	
GO:0090160	biolink:NamedThing	Golgi to lysosome transport	The directed movement of substances from the Golgi to lysosomes.	got7fsn_ti							tb	2009-12-08T08:35:13Z						biological_process											owl:Class	
GO:0002727	biolink:NamedThing	regulation of natural killer cell cytokine production	Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.	got7fsn_ti	regulation of NK cell cytokine production													biological_process											owl:Class	
GO:1900027	biolink:NamedThing	regulation of ruffle assembly	Any process that modulates the frequency, rate or extent of ruffle assembly.	got7fsn_ti	regulation of membrane ruffling|regulation of membrane ruffle formation						yaf	2012-01-12T05:00:49Z						biological_process											owl:Class	
PR:000015794	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001393	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019828	biolink:NamedThing	aspartic-type endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.	got7fsn_ti	aspartic protease inhibitor activity													molecular_function											owl:Class	
GO:1900022	biolink:NamedThing	regulation of D-erythro-sphingosine kinase activity	Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity.	got7fsn_ti	regulation of sphingosine kinase activity						bf	2012-01-11T04:30:29Z						biological_process											owl:Class	
OBO:GOCHE_22676	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000116	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045705	biolink:NamedThing	negative regulation of salivary gland boundary specification	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.	got7fsn_ti	down-regulation of salivary gland determination|down regulation of salivary gland determination|inhibition of salivary gland determination|downregulation of salivary gland determination|negative regulation of salivary gland determination													biological_process											owl:Class	
GO:0042156	biolink:NamedThing	obsolete zinc-mediated transcriptional activator activity	OBSOLETE. Initiates or upregulates transcription in the presence of zinc.	got7fsn_ti	zinc-mediated transcriptional activator activity				This term was obsoleted because it is defined as a Process term, i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.					True				molecular_function											owl:Class	
GO:0034177	biolink:NamedThing	positive regulation of toll-like receptor 12 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.	got7fsn_ti	positive regulation of toll-like receptor 12 signalling pathway|positive regulation of TLR12 signaling pathway													biological_process											owl:Class	
GO:0040026	biolink:NamedThing	positive regulation of vulval development	Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.	got7fsn_ti	stimulation of vulval development|up-regulation of vulval development|upregulation of vulval development|up regulation of vulval development|activation of vulval development													biological_process											owl:Class	
GO:1903252	biolink:NamedThing	hercynylcysteine sulfoxide metabolic process	The chemical reactions and pathways involving hercynylcysteine sulfoxide.	got7fsn_ti	hercynylcysteine sulfoxide metabolism						mah	2014-08-06T09:13:50Z						biological_process											owl:Class	
GO:0120222	biolink:NamedThing	regulation of blastocyst development	Any process that modulates the frequency, rate or extent of blastocyst development.	got7fsn_ti							krc	2020-02-17T19:59:20Z						biological_process											owl:Class	
GO:2000106	biolink:NamedThing	regulation of leukocyte apoptotic process	Any process that modulates the frequency, rate or extent of leukocyte apoptotic process.	got7fsn_ti	regulation of leukocyte apoptosis						mah	2010-09-15T01:42:05Z						biological_process											owl:Class	
GO:0097176	biolink:NamedThing	epoxide metabolic process	The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers.	got7fsn_ti	epoxide metabolism						pr	2011-10-10T11:29:49Z						biological_process											owl:Class	
GO:0003787	biolink:NamedThing	obsolete actin depolymerizing activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	actin depolymerizing activity			GO:0030042	This term was made obsolete because it represents a biological process.					True				molecular_function											owl:Class	
GO:0002531	biolink:NamedThing	regulation of heart contraction involved in acute-phase response	Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.	got7fsn_ti	regulation of heart contraction during acute phase response|regulation of cardiac contraction during acute phase response													biological_process											owl:Class	
GO:1990806	biolink:NamedThing	ligand-gated ion channel signaling pathway	A series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.	got7fsn_ti	ligand-gated ion channel signalling pathway						bhm	2015-07-20T12:09:56Z						biological_process											owl:Class	
GO:0048710	biolink:NamedThing	regulation of astrocyte differentiation	Any process that modulates the frequency, rate or extent of astrocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
CHEBI:26387	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098710	biolink:NamedThing	guanine import across plasma membrane	The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	guanine import into cell						dph	2012-12-06T14:52:43Z			GO:0061489			biological_process											owl:Class	
GO:1900874	biolink:NamedThing	heptadec-1-ene metabolic process	The chemical reactions and pathways involving heptadec-1-ene.	got7fsn_ti	heptadec-1-ene metabolism						tt	2012-06-13T01:49:51Z						biological_process											owl:Class	
GO:1902061	biolink:NamedThing	betaine aldehyde metabolic process	The chemical reactions and pathways involving betaine aldehyde.	got7fsn_ti	betaine aldehyde metabolism						di	2013-04-16T12:07:03Z						biological_process											owl:Class	
CHEBI:26377	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902231	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.	got7fsn_ti	activation of DNA damage response, signal transduction resulting in induction of apoptosis|upregulation of intrinsic apoptotic signaling pathway in response to DNA damage|activation of intrinsic apoptotic signaling pathway in response to DNA damage|up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage|up regulation of intrinsic apoptotic signaling pathway in response to DNA damage|up regulation of DNA damage response, signal transduction resulting in induction of apoptosis|upregulation of DNA damage response, signal transduction resulting in induction of apoptosis|up-regulation of DNA damage response, signal transduction resulting in induction of apoptosis|positive regulation of DNA damage response, signal transduction resulting in induction of apoptosis						rl	2013-06-14T09:40:03Z						biological_process											owl:Class	
GO:0008518	biolink:NamedThing	folate:anion antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF.	got7fsn_ti	reduced folate transporter|reduced folate transmembrane transporter activity|reduced folate carrier activity	https://github.com/geneontology/go-ontology/issues/15461										TC:2.A.48		molecular_function											owl:Class	
GO:1905720	biolink:NamedThing	cytoplasmic microtubule bundle	Any microtubule bundle that is part of a cytoplasm.	got7fsn_ti	microtubule fascicle of cytoplasm|microtubule bundle of cytoplasm						mah	2016-11-24T16:52:02Z						cellular_component											owl:Class	
GO:1904637	biolink:NamedThing	cellular response to ionomycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.	got7fsn_ti							sl	2015-08-31T14:39:25Z						biological_process											owl:Class	
GO:0032961	biolink:NamedThing	negative regulation of inositol trisphosphate biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.	got7fsn_ti	negative regulation of IP3 biosynthetic process|negative regulation of inositol trisphosphate synthesis|negative regulation of inositol trisphosphate biosynthesis|negative regulation of IP3 biosynthesis|negative regulation of myo-inositol trisphosphate biosynthesis|negative regulation of inositol trisphosphate formation|negative regulation of myo-inositol trisphosphate biosynthetic process|negative regulation of inositol trisphosphate anabolism													biological_process											owl:Class	
UBERON:0002086	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120074	biolink:NamedThing	regulation of endocardial cushion cell differentiation	Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.	got7fsn_ti							krc	2017-06-26T23:32:00Z						biological_process											owl:Class	
OIO:hasDbXref	biolink:NamedThing	database_cross_reference		got7fsn_ti																									owl:AnnotationProperty	
GO:2001102	biolink:NamedThing	hexasaccharide transport	The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:20:31Z						biological_process											owl:Class	
GO:0008319	biolink:NamedThing	obsolete prenyl protein specific endopeptidase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	prenyl protein specific endopeptidase activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0075280	biolink:NamedThing	regulation of uredinium development	Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.	got7fsn_ti														biological_process											owl:Class	
GO:0046643	biolink:NamedThing	regulation of gamma-delta T cell activation	Any process that modulates the frequency, rate or extent of gamma-delta T cell activation.	got7fsn_ti	regulation of gamma-delta T-lymphocyte activation|regulation of gamma-delta T-cell activation|regulation of gamma-delta T lymphocyte activation													biological_process											owl:Class	
GO:1901034	biolink:NamedThing	regulation of L-glutamine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-glutamine import into cell.	got7fsn_ti	regulation of L-glutamine import|regulation of L-glutamine uptake						al	2012-06-21T07:31:27Z						biological_process											owl:Class	
GO:0000313	biolink:NamedThing	organellar ribosome	A ribosome contained within a subcellular membrane-bounded organelle.	got7fsn_ti														cellular_component											owl:Class	
CHEBI:17748	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000571	biolink:NamedThing	regulation of interleukin-4-dependent isotype switching to IgE isotypes	Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.	got7fsn_ti	regulation of IL-4-dependent isotype switching to IgE isotypes						ebc	2011-04-03T09:20:11Z						biological_process											owl:Class	
GO:0045928	biolink:NamedThing	negative regulation of juvenile hormone metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.	got7fsn_ti	down-regulation of juvenile hormone metabolic process|down regulation of juvenile hormone metabolic process|inhibition of juvenile hormone metabolic process|downregulation of juvenile hormone metabolic process|negative regulation of juvenile hormone metabolism													biological_process											owl:Class	
CHEBI:64648	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002628	biolink:NamedThing	regulation of proteolysis associated with antigen processing and presentation	Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.	got7fsn_ti														biological_process											owl:Class	
GO:0044051	biolink:NamedThing	obsolete interaction with host via substance released by symbiont cytolysis	OBSOLETE. An interaction with the host organism mediated by a substance released via cytolysis of symbiont cells. Cytolysis is the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	interaction with host via substance released by cytolysis of symbiont				This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True				biological_process											owl:Class	
GO:2000722	biolink:NamedThing	regulation of cardiac vascular smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.	got7fsn_ti	regulation of heart vascular smooth muscle cell differentiation						vk	2011-06-08T08:47:58Z						biological_process											owl:Class	
GO:0009367	biolink:NamedThing	obsolete prepilin peptidase complex	OBSOLETE. An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group.	got7fsn_ti	prepilin peptidase complex				This term was made obsolete because prepilin peptidase is a single gene product, and there is no evidence that it acts as a multimer.					True				cellular_component											owl:Class	
GO:0106196	biolink:NamedThing	obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a nucleoside triphosphate	OBSOLETE. Catalysis of the translocation of inorganic anions linked to the hydrolysis of a nucleoside triphosphate.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:15:35Z		True		EC:7.3.2.-		molecular_function											owl:Class	
GO:0097184	biolink:NamedThing	response to azide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.	got7fsn_ti							pr	2011-11-16T10:00:58Z						biological_process											owl:Class	
CHEBI:37329	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:73678	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075518	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:25106	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061074	biolink:NamedThing	regulation of neural retina development	Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.	got7fsn_ti							dph	2010-03-16T11:47:05Z						biological_process											owl:Class	
GO:1904541	biolink:NamedThing	fungal-type cell wall disassembly involved in conjugation with cellular fusion	Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion.	got7fsn_ti	fungal-type cell wall disassembly involved in mating|fungal-type cell wall disassembly involved in cell fusion						al	2015-08-10T17:12:51Z						biological_process											owl:Class	
GO:0038010	biolink:NamedThing	positive regulation of signal transduction by receptor internalization	Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms.	got7fsn_ti	positive regulation of signaling pathway by receptor endocytosis						bf	2011-06-23T03:37:10Z						biological_process											owl:Class	
UBERON:0001821	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016909	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905307	biolink:NamedThing	response to miconazole	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.	got7fsn_ti							al	2016-07-06T11:55:22Z						biological_process											owl:Class	
GO:0021950	biolink:NamedThing	chemorepulsion involved in precerebellar neuron migration	The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration.	got7fsn_ti	negative chemotaxis involved in precerebellar neuron migration													biological_process											owl:Class	
GO:0050662	biolink:NamedThing	obsolete coenzyme binding	OBSOLETE. Binding to a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	got7fsn_ti					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group binding interactions that are not all chemically related by the fact that they may be used as a coenzyme.					True				molecular_function											owl:Class	
CHEBI:16709	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042079	biolink:NamedThing	obsolete GPI/GSI anchor metabolic process	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	GPI/GSI anchor metabolic process				This term was made obsolete because it is a composite term that represents two individual processes.	GO:0042081|GO:0006505				True				biological_process											owl:Class	
GO:2000251	biolink:NamedThing	positive regulation of actin cytoskeleton reorganization	Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.	got7fsn_ti	positive regulation of actin cytoskeleton remodeling|positive regulation of actin cytoskeleton reorganisation						vk	2010-11-11T01:25:32Z						biological_process											owl:Class	
GO:0005936	biolink:NamedThing	obsolete shmoo	OBSOLETE. The characteristic projection formed in response to mating pheromone by cells of Saccharomyces and other fungi with similar life cycles. Named after the Al Capp cartoon character, whose shape it resembles.	got7fsn_ti	shmoo				This term was made obsolete because it represents a type of whole cell rather than a cellular component. To update annotations, consider the external ontology term 'shmoo ; FAO:0001023'.	GO:0001400|GO:0005937				True				cellular_component											owl:Class	
GO:0033086	biolink:NamedThing	negative regulation of extrathymic T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation.	got7fsn_ti	negative regulation of extrathymic T cell development				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0099027	biolink:NamedThing	anchored component of presynaptic endocytic zone membrane	The component of the presynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	got7fsn_ti														cellular_component											owl:Class	
GO:0015557	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:26893	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000287	biolink:NamedThing	positive regulation of myotome development	Any process that activates or increases the frequency, rate or extent of myotome development.	got7fsn_ti							rl	2010-12-16T05:17:15Z						biological_process											owl:Class	
CHEBI:2651	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061746	biolink:NamedThing	obsolete single-stranded DNA-dependent GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19078			This term was obsoleted because there is no evidence that this reaction occurs under physiological conditions.		dph	2015-11-11T12:50:19Z		True				molecular_function											owl:Class	
GO:2001297	biolink:NamedThing	N(omega)-methyl-L-arginine catabolic process	The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine.	got7fsn_ti	N(omega)-methyl-L-arginine degradation|N(omega)-methyl-L-arginine breakdown|N(omega)-methyl-L-arginine catabolism						pr	2012-02-14T03:38:21Z						biological_process											owl:Class	
GO:0051414	biolink:NamedThing	response to cortisol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.	got7fsn_ti	response to hydrocortisone stimulus|response to cortisol stimulus													biological_process											owl:Class	
GO:0060193	biolink:NamedThing	positive regulation of lipase activity	Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.	got7fsn_ti														biological_process											owl:Class	
GO:0045999	biolink:NamedThing	negative regulation of ecdysteroid secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid.	got7fsn_ti	inhibition of ecdysteroid secretion|downregulation of ecdysteroid secretion|down-regulation of ecdysteroid secretion|down regulation of ecdysteroid secretion													biological_process											owl:Class	
CHEBI:58007	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001349	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010511	biolink:NamedThing	regulation of phosphatidylinositol biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.	got7fsn_ti														biological_process											owl:Class	
CHEBI:62980	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61085	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905746	biolink:NamedThing	positive regulation of mRNA cis splicing, via spliceosome	Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome.	got7fsn_ti							vw	2016-12-07T14:01:52Z						biological_process											owl:Class	
GO:1904997	biolink:NamedThing	regulation of leukocyte adhesion to arterial endothelial cell	Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.	got7fsn_ti							bc	2016-03-01T11:04:49Z						biological_process											owl:Class	
CHEBI:141496	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000991	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052487	biolink:NamedThing	obsolete negative regulation by organism of symbiont jasmonic acid-mediated defense response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by organism of symbiont jasmonic acid-mediated defense response|suppression by organism of symbiont JA-mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0033357	biolink:NamedThing	L-arabinose biosynthetic process	The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose.	got7fsn_ti	L-arabinose biosynthesis|L-arabinose formation|L-arabinose anabolism|L-arabinose synthesis													biological_process											owl:Class	
CHEBI:67201	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072530	biolink:NamedThing	purine-containing compound transmembrane transport	The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.	got7fsn_ti	purine-containing compound membrane transport				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2011-01-05T01:45:14Z						biological_process											owl:Class	
CHEBI:149484	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28808	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045100	biolink:NamedThing	obsolete desmin	OBSOLETE. A type of intermediate filament.	got7fsn_ti	desmin				This term was made obsolete because it represents a gene product.	GO:0045098				True				cellular_component											owl:Class	
GO:0106195	biolink:NamedThing	obsolete translocase activty acting on inorganic anions linked to oxidoreductase reactions	OBSOLETE. Catalysis of the translocation of inorganic anions linked to oxidoreductase reactions.	got7fsn_ti					This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:13:05Z		True		EC:7.3.1.-		molecular_function											owl:Class	
GO:1904829	biolink:NamedThing	regulation of aortic smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation.	got7fsn_ti							rph	2015-11-24T10:20:40Z						biological_process											owl:Class	
GO:0061279	biolink:NamedThing	epithelial cell migration involved in mesonephric distal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.	got7fsn_ti							dph	2010-09-02T01:20:56Z						biological_process											owl:Class	
UBERON:0000344	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901171	biolink:NamedThing	obsolete naphthalene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of naphthalene.	got7fsn_ti	naphthalene synthesis|naphthalene anabolism|naphthalene formation|naphthalene biosynthesis	https://github.com/geneontology/go-ontology/issues/20974			This term was obsoleted because there is no evidence that this process exists.		yaf	2012-07-19T09:34:11Z		True				biological_process											owl:Class	
GO:2000875	biolink:NamedThing	negative regulation of glyoxylate cycle	Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle.	got7fsn_ti	negative regulation of glyoxylate bypass						bf	2011-07-27T01:27:15Z						biological_process											owl:Class	
GO:0002846	biolink:NamedThing	regulation of T cell tolerance induction to tumor cell	Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell.	got7fsn_ti														biological_process											owl:Class	
CHEBI:38579	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57945	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000891	biolink:NamedThing	cellobiose metabolic process	The chemical reactions and pathways involving a cellobiose.	got7fsn_ti	cellobiose metabolism						jl	2011-07-28T01:35:35Z						biological_process											owl:Class	
GO:1903843	biolink:NamedThing	cellular response to arsenite ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.	got7fsn_ti							mr	2015-01-22T19:56:14Z						biological_process											owl:Class	
GO:0048784	biolink:NamedThing	pigment biosynthetic process involved in pigment granule maturation	The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.	got7fsn_ti	pigment biosynthetic process during pigment granule maturation													biological_process											owl:Class	
GO:0072720	biolink:NamedThing	response to dithiothreitol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.	got7fsn_ti	response to 1,4-dithiothreitol|response to DTT						mah	2012-05-09T11:08:58Z						biological_process											owl:Class	
GO:0009188	biolink:NamedThing	ribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	ribonucleoside diphosphate formation|ribonucleoside diphosphate anabolism|ribonucleoside diphosphate biosynthesis|ribonucleoside diphosphate synthesis													biological_process											owl:Class	
GO:0010801	biolink:NamedThing	negative regulation of peptidyl-threonine phosphorylation	Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	got7fsn_ti														biological_process											owl:Class	
GO:0000381	biolink:NamedThing	regulation of alternative mRNA splicing, via spliceosome	Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.	got7fsn_ti	splice site selection|regulation of alternative nuclear mRNA splicing, via spliceosome													biological_process											owl:Class	
GO:1905918	biolink:NamedThing	regulation of CoA-transferase activity	Any process that modulates the frequency, rate or extent of CoA-transferase activity.	got7fsn_ti							bc	2017-02-08T13:00:48Z						biological_process											owl:Class	
GO:2001086	biolink:NamedThing	laminarabiose transport	The directed movement of a laminarabioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T12:55:01Z						biological_process											owl:Class	
GO:0051105	biolink:NamedThing	regulation of DNA ligation	Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.	got7fsn_ti														biological_process											owl:Class	
GO:0052564	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072630	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150106	biolink:NamedThing	regulation of protein localization to cell-cell junction	Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction.	got7fsn_ti							bc	2019-06-11T11:17:15Z						biological_process											owl:Class	
GO:0046709	biolink:NamedThing	IDP catabolic process	The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.	got7fsn_ti	IDP breakdown|IDP catabolism|IDP degradation													biological_process											owl:Class	
GO:1904620	biolink:NamedThing	cellular response to dimethyl sulfoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.	got7fsn_ti	cellular response to DMSO						sl	2015-08-27T19:14:07Z						biological_process											owl:Class	
CHEBI:61304	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:72761	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904357	biolink:NamedThing	negative regulation of telomere maintenance via telomere lengthening	Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.	got7fsn_ti	down regulation of telomere maintenance via telomere lengthening|downregulation of telomere maintenance via telomere lengthening|down-regulation of telomere maintenance via telomere lengthening|inhibition of telomere maintenance via telomere lengthening						nc	2015-06-12T16:53:22Z						biological_process											owl:Class	
GO:0090034	biolink:NamedThing	regulation of chaperone-mediated protein complex assembly	Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.	got7fsn_ti							tb	2009-08-03T11:12:37Z						biological_process											owl:Class	
GO:1905456	biolink:NamedThing	regulation of lymphoid progenitor cell differentiation	Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation.	got7fsn_ti							rz	2016-09-16T12:32:40Z						biological_process											owl:Class	
GO:0030996	biolink:NamedThing	obsolete mitotic cell cycle arrest in response to nitrogen starvation	OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen.	got7fsn_ti	cell cycle arrest in response to nitrogen starvation				This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.					True				biological_process											owl:Class	
PR:000001245	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072155	biolink:NamedThing	epithelial cell migration involved in nephron tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis.	got7fsn_ti							mah	2010-02-24T02:21:25Z						biological_process											owl:Class	
CHEBI:28324	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002874	biolink:NamedThing	regulation of chronic inflammatory response to antigenic stimulus	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0031275	biolink:NamedThing	obsolete regulation of lateral pseudopodium assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.	got7fsn_ti	regulation of lateral pseudopodium formation	https://github.com/geneontology/go-ontology/issues/21738			The regulation of lateral pseudopodium assembly terms were not used consistently. The negative regulation term has been replaced by GO:0120320 lateral pseudopodium retraction.					True				biological_process											owl:Class	
GO:0030321	biolink:NamedThing	transepithelial chloride transport	The directed movement of chloride ions from one side of an epithelium to the other.	got7fsn_ti														biological_process											owl:Class	
OBO:GOCHE_33284	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000566	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta T cell proliferation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.	got7fsn_ti							ebc	2011-04-03T09:03:24Z						biological_process											owl:Class	
GO:0005573	biolink:NamedThing	obsolete telomerase RNA	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	telomerase RNA			GO:0000332	This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
GO:0106082	biolink:NamedThing	sucrose import across plasma membrane	The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							hjd	2017-12-28T18:16:29Z						biological_process											owl:Class	
GO:0045193	biolink:NamedThing	obsolete acetylated low-density lipoprotein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetylated low-density lipoproteins.	got7fsn_ti	acetylated low-density lipoprotein breakdown|acetylated low-density lipoprotein degradation|acetylated low-density lipoprotein catabolism|acetylated low-density lipoprotein catabolic process|Ac-LDL catabolic process|Ac-LDL catabolism				This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds.					True				biological_process											owl:Class	
GO:0010351	biolink:NamedThing	lithium ion transport	The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	lithium transport													biological_process											owl:Class	
GO:0007590	biolink:NamedThing	obsolete fat body metabolic process (sensu Insecta)	OBSOLETE. The chemical reactions and pathways involving the fat body. A fat body is a fat-containing cellular structure which serves as an energy reserve. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).	got7fsn_ti	fat body metabolic process (sensu Insecta)				This term was made obsolete because it represents metabolism within the fat body not of the fat body.					True				biological_process											owl:Class	
GO:0110098	biolink:NamedThing	positive regulation of calcium import into the mitochondrion	Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.	got7fsn_ti							kmv	2018-02-28T00:39:13Z						biological_process											owl:Class	
GO:0006600	biolink:NamedThing	creatine metabolic process	The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.	got7fsn_ti	creatine metabolism													biological_process											owl:Class	
GO:2000475	biolink:NamedThing	negative regulation of opioid receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway.	got7fsn_ti	negative regulation of opioid receptor signalling pathway						bf	2011-03-09T09:41:03Z						biological_process											owl:Class	
GO:1900853	biolink:NamedThing	negative regulation of terrequinone A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of terrequinone A biosynthetic process.	got7fsn_ti	downregulation of terrequinone A biosynthetic process|down-regulation of terrequinone A biosynthetic process|down regulation of terrequinone A biosynthetic process						di	2012-06-07T09:47:30Z						biological_process											owl:Class	
GO:0075091	biolink:NamedThing	obsolete positive regulation by host of symbiont signal transduction mediated by G-protein alpha subunit	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:2000254	biolink:NamedThing	regulation of male germ cell proliferation	Any process that modulates the frequency, rate or extent of male germ cell proliferation.	got7fsn_ti							dph	2010-11-18T09:29:44Z						biological_process											owl:Class	
GO:0046495	biolink:NamedThing	nicotinamide riboside metabolic process	The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.	got7fsn_ti	nicotinamide riboside metabolism|N-ribosylnicotinamide metabolic process													biological_process											owl:Class	
GO:1901939	biolink:NamedThing	(-)-exo-alpha-bergamotene catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene.	got7fsn_ti	(-)-exo-alpha-bergamotene catabolism|(-)-exo-alpha-bergamotene degradation|(-)-exo-alpha-bergamotene breakdown						ms	2013-02-18T14:55:27Z						biological_process											owl:Class	
GO:0060154	biolink:NamedThing	obsolete cellular process regulating host cell cycle in response to virus	OBSOLETE. Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus.	got7fsn_ti					The reason for obsoletion is that based on the definition, it is not clear that this process exists.					True				biological_process											owl:Class	
GO:0075236	biolink:NamedThing	obsolete positive regulation of zoospore movement on or near host	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
GO:0062111	biolink:NamedThing	zinc ion import into organelle	The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle.	got7fsn_ti							dph	2019-02-05T15:27:38Z						biological_process											owl:Class	
GO:0019858	biolink:NamedThing	cytosine metabolic process	The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.	got7fsn_ti	cytosine metabolism													biological_process											owl:Class	
GO:1904010	biolink:NamedThing	response to Aroclor 1254	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.	got7fsn_ti							sl	2015-03-06T18:35:00Z						biological_process											owl:Class	
GO:0010314	biolink:NamedThing	phosphatidylinositol-5-phosphate binding	Binding to phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position.	got7fsn_ti														molecular_function											owl:Class	
GO:0009003	biolink:NamedThing	obsolete signal peptidase activity	OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor.	got7fsn_ti	signal peptidase activity			GO:0008233	This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products.					True				molecular_function											owl:Class	
GO:1902363	biolink:NamedThing	regulation of protein localization to spindle pole body	Any process that modulates the frequency, rate or extent of protein localization to spindle pole body.	got7fsn_ti	regulation of protein localisation to spindle pole body						vw	2013-08-15T16:38:07Z						biological_process											owl:Class	
GO:0098989	biolink:NamedThing	NMDA selective glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	got7fsn_ti														biological_process											owl:Class	
GO:0033471	biolink:NamedThing	GDP-L-galactose metabolic process	The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-L-galactose metabolism													biological_process											owl:Class	
CL:0000844	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903701	biolink:NamedThing	substantia propria of cornea development	The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.	got7fsn_ti	corneal stroma development|substantia propria development|stroma of cornea development						cls	2014-12-03T13:12:09Z						biological_process											owl:Class	
GO:1905892	biolink:NamedThing	negative regulation of cellular response to thapsigargin	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to thapsigargin.	got7fsn_ti	down-regulation of cellular response to thapsigargin|downregulation of cellular response to thapsigargin|inhibition of cellular response to thapsigargin|down regulation of cellular response to thapsigargin						bc	2017-02-01T11:36:15Z						biological_process											owl:Class	
GO:0052358	biolink:NamedThing	obsolete catabolism by host of symbiont glucan	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21396			This term was obsoleted because there is no evidence it exists.					True				biological_process											owl:Class	
CHEBI:16188	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150163	biolink:NamedThing	miRNA-mediated activation of transcription by RNA polymerase II	Any process mediated by a microRNA (miRNA) that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	got7fsn_ti							bc	2020-01-14T12:08:14Z						biological_process											owl:Class	
GO:0070036	biolink:NamedThing	obsolete GTP-dependent helicase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix.	got7fsn_ti					The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo).					True				molecular_function											owl:Class	
GO:1990771	biolink:NamedThing	clathrin-dependent extracellular exosome endocytosis	The clathrin-mediated endocytosis of an extracellular exosome.	got7fsn_ti	exosome related|clathrin-mediated extracellular exosome endocytosis						sl	2015-06-15T17:03:57Z						biological_process											owl:Class	
GO:0110044	biolink:NamedThing	regulation of cell cycle switching, mitotic to meiotic cell cycle	Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.	got7fsn_ti	sexual differentiation	https://github.com/geneontology/go-ontology/issues/20926					kmv	2017-08-08T21:24:45Z						biological_process											owl:Class	
CL:0000584	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0017072	biolink:NamedThing	obsolete tubulin-specific chaperone activity	OBSOLETE. Assists in the correct, non-covalent assembly of tubulin-containing structures in vivo, but is not a component of the assembled structures when performing its normal biological function.	got7fsn_ti	tubulin-specific chaperone activity				This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function.	GO:0007021				True				molecular_function											owl:Class	
CHEBI:26435	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072212	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in metanephros development	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the metanephros progresses from its initial formation to the mature state.	got7fsn_ti							mah	2010-03-18T01:14:09Z						biological_process											owl:Class	
GO:0120142	biolink:NamedThing	positive regulation of ecdysone receptor-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.	got7fsn_ti							krc	2018-03-22T17:25:00Z						biological_process											owl:Class	
CHEBI:45979	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045535	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015880	biolink:NamedThing	coenzyme A transport	The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	got7fsn_ti														biological_process											owl:Class	
CHEBI:58442	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007201	biolink:NamedThing	obsolete G-protein dissociation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	G-protein dissociation				This term was made obsolete because the dissociation of heterotrimeric G protein subunits is a consequence of a conformational change, which is in turn a consequence of ligand binding; it does not require multiple activities specifically to bring about.					True				biological_process											owl:Class	
PR:000001379	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001875	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902920	biolink:NamedThing	poly(hydroxyvalerate) metabolic process	The chemical reactions and pathways involving poly(hydroxyvalerate).	got7fsn_ti	poly(hydroxyvalerate) metabolism						tt	2014-04-21T19:12:32Z						biological_process											owl:Class	
GO:0061856	biolink:NamedThing	Golgi calcium ion transmembrane transport	A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti							dph	2017-03-14T16:08:23Z						biological_process											owl:Class	
GO:0004005	biolink:NamedThing	obsolete plasma membrane cation-transporting ATPase	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	plasma membrane cation-transporting ATPase				This term was made obsolete because it contains both component and function information.	GO:0005886|GO:0019829				True				molecular_function											owl:Class	
GO:0021919	biolink:NamedThing	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the spatial identity of regions along the dorsal-ventral axis of the spinal cord.	got7fsn_ti	BMP signaling pathway in spinal cord dorsoventral patterning|bone morphogenetic protein signaling pathway in spinal cord dorsal-ventral patterning|BMP signalling pathway involved in spinal cord dorsal-ventral patterning|BMP signaling pathway involved in spinal cord dorsal-ventral patterning|bone morphogenetic protein signalling pathway involved in spinal cord dorsal-ventral patterning													biological_process											owl:Class	
GO:0001324	biolink:NamedThing	obsolete age-dependent response to oxidative stress involved in chronological cell aging	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.	got7fsn_ti	age-dependent response to oxidative stress during chronological cell ageing|age-dependent response to oxidative stress during chronological cell aging	https://github.com/geneontology/go-ontology/issues/18632			This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398				True				biological_process											owl:Class	
CL:0002608	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032374	biolink:NamedThing	regulation of cholesterol transport	Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
PO:0005352	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000416	biolink:NamedThing	positive regulation of histone H3-K36 methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.	got7fsn_ti	up-regulation of histone H3-K36 methylation|activation of histone H3-K36 methylation|stimulation of histone H3-K36 methylation|up regulation of histone H3-K36 methylation|upregulation of histone H3-K36 methylation													biological_process											owl:Class	
GO:0016184	biolink:NamedThing	obsolete synaptic vesicle retrieval	OBSOLETE. Return of a vesicle from the postsynaptic membrane to presynaptic membrane.	got7fsn_ti	synaptic vesicle retrieval				This term was made obsolete because it was wrongly defined.	GO:0016192				True				biological_process											owl:Class	
GO:0016018	biolink:NamedThing	cyclosporin A binding	Binding to cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids.	got7fsn_ti	cyclophilin													molecular_function											owl:Class	
UBERON:0001008	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905257	biolink:NamedThing	positive regulation of RNA binding transcription factor activity	Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity.	got7fsn_ti	up-regulation of RNA binding transcription factor activity|up regulation of RNA binding transcription factor activity|activation of RNA binding transcription factor activity|upregulation of RNA binding transcription factor activity						bf	2016-06-13T11:29:27Z						biological_process											owl:Class	
GO:0048145	biolink:NamedThing	regulation of fibroblast proliferation	Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.	got7fsn_ti														biological_process											owl:Class	
CHEBI:71339	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015958	biolink:NamedThing	bis(5'-nucleosidyl) oligophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.	got7fsn_ti	bis(5'-nucleosidyl) oligophosphate breakdown|bis(5'-nucleosidyl) oligophosphate catabolism|bis(5'-nucleosidyl) oligophosphate degradation													biological_process											owl:Class	
GO:0090270	biolink:NamedThing	regulation of fibroblast growth factor production	Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	got7fsn_ti							tb	2010-02-05T02:33:33Z						biological_process											owl:Class	
GO:0052241	biolink:NamedThing	obsolete positive chemotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	positive chemotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
UBERON:0000349	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003710	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902322	biolink:NamedThing	regulation of methyl-branched fatty acid biosynthetic process	Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.	got7fsn_ti	regulation of methyl-branched fatty acid anabolism|regulation of methyl-branched fatty acid biosynthesis|regulation of methyl-branched fatty acid formation|regulation of methyl-branched fatty acid synthesis						kmv	2013-07-24T20:15:15Z						biological_process											owl:Class	
PR:000006013	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010913	biolink:NamedThing	regulation of sterigmatocystin biosynthetic process	Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	got7fsn_ti														biological_process											owl:Class	
GO:0005545	biolink:NamedThing	1-phosphatidylinositol binding	Binding to a phosphatidylinositol, a glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.	got7fsn_ti														molecular_function											owl:Class	
GO:1905737	biolink:NamedThing	positive regulation of L-proline import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane.	got7fsn_ti							vw	2016-12-04T20:42:33Z						biological_process											owl:Class	
CHEBI:58040	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090086	biolink:NamedThing	negative regulation of protein deubiquitination	Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.	got7fsn_ti							tb	2009-10-23T11:18:06Z						biological_process											owl:Class	
GO:0032381	biolink:NamedThing	negative regulation of intracellular sterol transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells.	got7fsn_ti	down regulation of intracellular sterol transport|down-regulation of intracellular sterol transport|downregulation of intracellular sterol transport|inhibition of intracellular sterol transport													biological_process											owl:Class	
GO:1905420	biolink:NamedThing	vascular associated smooth muscle cell differentiation involved in phenotypic switching	Any vascular smooth muscle cell differentiation that is involved in phenotypic switching.	got7fsn_ti	vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|vascular smooth muscle cell differentiation involved in phenotypic dimorphism|vascular associated smooth muscle cell differentiation involved in phenotypic switching|vascular smooth muscle cell differentiation involved in phenotypic switching|VSMC differentiation involved in phenotypic dimorphism|VSMC differentiation involved in phenotypic switching						rph	2016-09-05T12:43:46Z						biological_process											owl:Class	
GO:0075320	biolink:NamedThing	negative regulation of ascus development	Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.	got7fsn_ti														biological_process											owl:Class	
GO:0031194	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008025	biolink:NamedThing	obsolete diazepam binding inhibitor activity	OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters.	got7fsn_ti	DBI|diazepam binding inhibitor activity|diazepam-binding inhibitor activity				This term was made obsolete because it represents a multifunctional gene product.	GO:0050811|GO:0030156|GO:0050809|GO:0050796|GO:0050812|GO:0004857|GO:0050810				True				molecular_function											owl:Class	
CHEBI:24966	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001097	biolink:NamedThing	laminaritriose transport	The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T02:11:36Z						biological_process											owl:Class	
GO:0075107	biolink:NamedThing	obsolete positive regulation by symbiont of host adenylate cyclase activity	OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by symbiont of host adenylylcyclase activity|positive regulation by symbiont of host adenylyl cyclase activity|positive regulation by symbiont of host adenyl cyclase activity|positive regulation by symbiont of host 3',5'-cyclic AMP synthetase activity|positive regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity	This term was obsoleted because it represents a molecular function.			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
CHEBI:45906	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_1000035	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009155	biolink:NamedThing	purine deoxyribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	purine deoxyribonucleotide degradation|purine deoxyribonucleotide catabolism|purine deoxyribonucleotide breakdown													biological_process											owl:Class	
UBERON:0002107	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052462	biolink:NamedThing	obsolete modulation by host of symbiont phagocytosis	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
CHEBI:38597	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000074	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043861	biolink:NamedThing	agmatine:putrescine antiporter activity	Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out).	got7fsn_ti	agmatine/putrescine antiporter activity|agmatine-putrescine antiporter activity													molecular_function											owl:Class	
GO:0045346	biolink:NamedThing	regulation of MHC class II biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.	got7fsn_ti	regulation of MHC class II formation|regulation of major histocompatibility complex class II biosynthetic process|regulation of MHC class II anabolism|regulation of MHC class II synthesis|regulation of major histocompatibility complex class II biosynthesis|regulation of MHC class II biosynthesis													biological_process											owl:Class	
CHEBI:24287	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072285	biolink:NamedThing	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.	got7fsn_ti							mah	2010-04-01T03:43:31Z						biological_process											owl:Class	
GO:0042537	biolink:NamedThing	benzene-containing compound metabolic process	The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.	got7fsn_ti	benzene and derivative metabolic process|benzene and derivative metabolism|benzene-containing compound metabolism													biological_process											owl:Class	
GO:0110040	biolink:NamedThing	pharynx morphogenesis	The process in which the anatomical structures of the pharynx are generated and organized.	got7fsn_ti							kmv	2017-07-24T20:51:28Z						biological_process											owl:Class	
GO:0015634	biolink:NamedThing	obsolete lipopolysaccharide exporter activity	OBSOLETE. Enables the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.	got7fsn_ti	LPS exporter activity	https://github.com/geneontology/go-ontology/issues/17202			This term was obsoleted because export is a process, not a function.					True				molecular_function											owl:Class	
GO:0070599	biolink:NamedThing	fungal-type cell wall (1->3)-alpha-glucan metabolic process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.	got7fsn_ti	ascospore wall 1,3-alpha-glucan metabolism|ascospore wall alpha-1,3 glucan metabolic process|ascospore wall 1,3-alpha-glucan metabolic process|ascospore wall alpha-1,3 glucan metabolism						mah	2009-04-28T04:07:23Z						biological_process											owl:Class	
GO:1900632	biolink:NamedThing	tridecane biosynthetic process	The chemical reactions and pathways resulting in the formation of tridecane.	got7fsn_ti	tridecane anabolism|tridecane biosynthesis|tridecane synthesis|tridecane formation						tt	2012-05-21T06:41:37Z						biological_process											owl:Class	
GO:0015780	biolink:NamedThing	nucleotide-sugar transmembrane transport	The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	got7fsn_ti	nucleotide-sugar transport													biological_process											owl:Class	
GO:0060400	biolink:NamedThing	negative regulation of growth hormone receptor signaling pathway	Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.	got7fsn_ti	negative regulation of growth hormone receptor signalling pathway													biological_process											owl:Class	
GO:0002715	biolink:NamedThing	regulation of natural killer cell mediated immunity	Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity.	got7fsn_ti	regulation of NK cell mediated immunity|regulation of natural killer cell activity										GO:0045845			biological_process											owl:Class	
SO:0000274	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072448	biolink:NamedThing	obsolete detection of stimulus involved in G1 cell size control checkpoint	OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition size control checkpoint.	got7fsn_ti	sensing involved in mitotic cell cycle G1/S transition size control checkpoint|mitotic cell cycle G1/S transition size control checkpoint sensor mechanism|mitotic cell cycle G1/S transition size control checkpoint sensor process|detection of stimulus involved in mitotic cell cycle G1/S transition size control checkpoint	https://github.com/geneontology/go-ontology/issues/20976			This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T10:56:32Z		True				biological_process											owl:Class	
GO:0018924	biolink:NamedThing	mandelate metabolic process	The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.	got7fsn_ti	mandelate metabolism|mandelic acid metabolism|mandelic acid metabolic process											UM-BBD_pathwayID:mca		biological_process											owl:Class	
CHEBI:57560	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045473	biolink:NamedThing	obsolete response to ethanol (sensu Insecta)	OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.	got7fsn_ti	response to ethanol (sensu Insecta)				This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.	GO:0048149				True				biological_process											owl:Class	
GO:0046450	biolink:NamedThing	dethiobiotin metabolic process	The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms.	got7fsn_ti	desthiobiotin metabolic process|desthiobiotin metabolism|dethiobiotin metabolism													biological_process											owl:Class	
GO:1900336	biolink:NamedThing	regulation of methane biosynthetic process from carbon monoxide	Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide.	got7fsn_ti							tt	2012-04-06T02:03:15Z						biological_process											owl:Class	
GO:0032727	biolink:NamedThing	positive regulation of interferon-alpha production	Any process that activates or increases the frequency, rate, or extent of interferon-alpha production.	got7fsn_ti	activation of interferon-alpha production|up-regulation of interferon-alpha production|upregulation of interferon-alpha production|up regulation of interferon-alpha production|stimulation of interferon-alpha production|positive regulation of interferon-alpha secretion|positive regulation of interferon-alpha biosynthetic process										GO:0045356|GO:1902741			biological_process											owl:Class	
GO:0060542	biolink:NamedThing	regulation of strand invasion	Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.	got7fsn_ti							dph	2009-04-13T01:28:41Z						biological_process											owl:Class	
CHEBI:64627	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64668	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0039601	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:61417	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097679	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046434	biolink:NamedThing	organophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.	got7fsn_ti	organophosphate catabolism|organophosphate breakdown|organophosphate degradation													biological_process											owl:Class	
GO:0098692	biolink:NamedThing	noradrenergic synapse	A synapse that uses noradrenaline as a neurotransmitter.	got7fsn_ti							dos	2017-03-07T14:57:24Z						cellular_component											owl:Class	
PR:000001146	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16933	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050895	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000037	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005994	biolink:NamedThing	melibiose metabolic process	The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.	got7fsn_ti	melibiose metabolism													biological_process											owl:Class	
GO:1905210	biolink:NamedThing	regulation of fibroblast chemotaxis	Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.	got7fsn_ti							sl	2016-06-02T20:08:42Z						biological_process											owl:Class	
CL:0000287	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905046	biolink:NamedThing	positive regulation of Schwann cell proliferation involved in axon regeneration	Any process that activates or increases the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.	got7fsn_ti	up regulation of Schwann cell proliferation involved in axon regeneration|up-regulation of Schwann cell proliferation involved in axon regeneration|upregulation of Schwann cell proliferation involved in axon regeneration|activation of Schwann cell proliferation involved in axon regeneration						rph	2016-03-11T14:47:54Z						biological_process											owl:Class	
GO:0001529	biolink:NamedThing	obsolete elastin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	elastin			GO:0030023	This term was made obsolete because it represents a gene product.					True				cellular_component											owl:Class	
GO:0097636	biolink:NamedThing	intrinsic component of autophagosome membrane	The component of the autophagosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic component of autophagic vacuole membrane|intrinsic to autophagic vacuole membrane													cellular_component											owl:Class	
CHEBI:57887	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57499	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_37845	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000392	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005118	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000164	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061901	biolink:NamedThing	regulation of 1-phosphatidylinositol-3-kinase activity	Any process that modulates the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity.	got7fsn_ti							dph	2017-06-22T19:34:56Z						biological_process											owl:Class	
GO:0031111	biolink:NamedThing	negative regulation of microtubule polymerization or depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.	got7fsn_ti	down regulation of microtubule polymerization or depolymerization|downregulation of microtubule polymerization or depolymerization|inhibition of microtubule polymerization or depolymerization|down-regulation of microtubule polymerization or depolymerization													biological_process											owl:Class	
GO:0009263	biolink:NamedThing	deoxyribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	got7fsn_ti	deoxyribonucleotide anabolism|deoxyribonucleotide formation|deoxyribonucleotide biosynthesis|deoxyribonucleotide synthesis													biological_process											owl:Class	
GO:1904207	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071362	biolink:NamedThing	cellular response to ether	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.	got7fsn_ti							mah	2009-12-11T03:03:22Z						biological_process											owl:Class	
GO:0005626	biolink:NamedThing	obsolete insoluble fraction	OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water.	got7fsn_ti	insoluble fraction|particle-bound				This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005575				True				cellular_component											owl:Class	
GO:0042306	biolink:NamedThing	regulation of protein import into nucleus	Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.	got7fsn_ti	regulation of protein transport from cytoplasm to nucleus|regulation of protein import into cell nucleus|regulation of protein-nucleus import													biological_process											owl:Class	
UBERON:0004176	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001366	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001782	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000890	biolink:NamedThing	cellodextrin catabolic process	The chemical reactions and pathways resulting in the breakdown of a cellodextrin.	got7fsn_ti	cellodextrin catabolism						jl	2011-07-28T01:05:21Z						biological_process											owl:Class	
GO:1902202	biolink:NamedThing	regulation of hepatocyte growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.	got7fsn_ti	regulation of HGF receptor signaling pathway|regulation of HGF receptor signalling pathway|regulation of Met signaling pathway						lb	2013-06-10T13:20:45Z						biological_process											owl:Class	
GO:2000892	biolink:NamedThing	cellobiose catabolic process	The chemical reactions and pathways resulting in the breakdown of a cellobiose.	got7fsn_ti	cellobiose catabolism						jl	2011-07-28T01:35:38Z						biological_process											owl:Class	
CHEBI:57277	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045983	biolink:NamedThing	positive regulation of purine nucleobase metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.	got7fsn_ti	positive regulation of purine base metabolic process|activation of purine base metabolic process|positive regulation of purine base metabolism|stimulation of purine base metabolic process|up regulation of purine base metabolic process|up-regulation of purine base metabolic process|upregulation of purine base metabolic process													biological_process											owl:Class	
GO:0046447	biolink:NamedThing	terpenoid indole alkaloid metabolic process	The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).	got7fsn_ti	terpenoid indole alkaloid metabolism													biological_process											owl:Class	
GO:0010807	biolink:NamedThing	regulation of synaptic vesicle priming	Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.	got7fsn_ti														biological_process											owl:Class	
GO:0070335	biolink:NamedThing	aspartate binding	Binding to aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.	got7fsn_ti	aspartic acid binding													molecular_function											owl:Class	
CL:1000147	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075105	biolink:NamedThing	obsolete negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction				The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:1901515	biolink:NamedThing	poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity	Enables the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of a membrane to the other.	got7fsn_ti							jl	2012-10-18T11:57:04Z						molecular_function											owl:Class	
GO:0042119	biolink:NamedThing	neutrophil activation	The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	got7fsn_ti														biological_process											owl:Class	
CHEBI:64409	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052454	biolink:NamedThing	obsolete modulation by organism of symbiont jasmonic acid-mediated defense response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of symbiont JA-mediated defense response|modulation by organism of symbiont jasmonic acid-mediated defense response				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0030458	biolink:NamedThing	obsolete activation of MAPKKK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of MAPKKK (mating sensu Fungi)			GO:0000750	This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
CHEBI:64482	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033321	biolink:NamedThing	homomethionine metabolic process	The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.	got7fsn_ti	homomethionine metabolism													biological_process											owl:Class	
GO:0030063	biolink:NamedThing	obsolete murein sacculus	OBSOLETE. A structure formed of the cross-linked polymer peptidoglycan (also called murein) that forms a covalently closed net around a bacterial cell, and imparts structural stability to the bacterial cell wall.	got7fsn_ti	murein sacculus|peptidoglycan layer				This term was made obsolete because it was defined inaccurately.	GO:0009276				True				cellular_component											owl:Class	
GO:2000766	biolink:NamedThing	negative regulation of cytoplasmic translation	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.	got7fsn_ti							vw	2011-06-20T10:39:23Z						biological_process											owl:Class	
CHEBI:57595	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16526	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000075	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0010202	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67036	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0036066	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903835	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0099644	biolink:NamedThing	protein localization to presynaptic membrane	A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane.	got7fsn_ti	protein localization in presynaptic membrane|protein localisation in presynaptic membrane|protein localisation to presynaptic membrane													biological_process											owl:Class	
GO:0002895	biolink:NamedThing	regulation of central B cell tolerance induction	Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.	got7fsn_ti														biological_process											owl:Class	
GO:0002852	biolink:NamedThing	regulation of T cell mediated cytotoxicity directed against tumor cell target	Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.	got7fsn_ti														biological_process											owl:Class	
GO:0106248	biolink:NamedThing	positive regulation of poly(A)-specific ribonuclease activity	Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity.	got7fsn_ti							hjd	2020-02-03T19:04:00Z						biological_process											owl:Class	
GO:0045798	biolink:NamedThing	negative regulation of chromatin assembly or disassembly	Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin assembly or disassembly.	got7fsn_ti	down-regulation of chromatin assembly or disassembly|down regulation of chromatin assembly or disassembly|downregulation of chromatin assembly or disassembly|negative regulation of chromatin assembly/disassembly|inhibition of chromatin assembly or disassembly													biological_process											owl:Class	
GO:0043913	biolink:NamedThing	obsolete chromosome segregation-directing complex	OBSOLETE. A trimeric protein complex which in E. coli is composed of the subunits MreB, MreC and MreD. The complex directs longitudinal cell wall synthesis, maintaining cell morphology.	got7fsn_ti	MreBCD complex|longitudinal peptidoglycan synthesis-directing complex|chromosome segregation directing complex	https://github.com/geneontology/go-ontology/issues/19794			This term was obsoleted because the three proteins mentioned in the definition are not part of the same complex.					True				cellular_component											owl:Class	
GO:0016090	biolink:NamedThing	prenol metabolic process	The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.	got7fsn_ti	prenol metabolism													biological_process											owl:Class	
GO:0031333	biolink:NamedThing	negative regulation of protein-containing complex assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.	got7fsn_ti	downregulation of protein complex assembly|inhibition of protein complex assembly|negative regulation of protein complex assembly|down regulation of protein complex assembly|down-regulation of protein complex assembly													biological_process											owl:Class	
GO:0097307	biolink:NamedThing	response to farnesol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.	got7fsn_ti							pr	2012-05-15T03:51:31Z						biological_process											owl:Class	
SO:0000651	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005552	biolink:NamedThing	obsolete polyubiquitin	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	polyubiquitin				This term was made obsolete because it represents a gene product and not a molecular function.	GO:0000209				True				molecular_function											owl:Class	
PR:000001548	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904636	biolink:NamedThing	response to ionomycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.	got7fsn_ti							sl	2015-08-31T14:39:18Z						biological_process											owl:Class	
GO:0048548	biolink:NamedThing	regulation of pinocytosis	Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.	got7fsn_ti														biological_process											owl:Class	
GO:1903496	biolink:NamedThing	response to 11-deoxycorticosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.	got7fsn_ti							mr	2014-09-25T17:01:35Z						biological_process											owl:Class	
CHEBI:61384	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33237	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140341	biolink:NamedThing	phosphatidylethanolamine floppase activity	Catalysis of the movement of phosphatidylethanolamine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	got7fsn_ti	phosphatidylethanolamine floppase activity (cytosolic to exoplasmic leaftlet)						pg	2019-05-16T11:40:45Z						molecular_function											owl:Class	
GO:0030449	biolink:NamedThing	regulation of complement activation	Any process that modulates the frequency, rate or extent of complement activation.	got7fsn_ti	regulation of complement cascade													biological_process											owl:Class	
GO:1901929	biolink:NamedThing	alpha-copaene metabolic process	The chemical reactions and pathways involving alpha-copaene.	got7fsn_ti	alpha-copaene metabolism						ms	2013-02-18T14:54:39Z						biological_process											owl:Class	
CHEBI:19569	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000892	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000008998	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57588	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004805	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21168	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009202	biolink:NamedThing	deoxyribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	deoxyribonucleoside triphosphate formation|deoxyribonucleoside triphosphate synthesis|deoxyribonucleoside triphosphate anabolism|deoxyribonucleoside triphosphate biosynthesis													biological_process											owl:Class	
CHEBI:64640	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015622	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904910	biolink:NamedThing	regulation of establishment of RNA localization to telomere	Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere.	got7fsn_ti	regulation of establishment of RNA localisation to telomere						rph	2016-01-19T10:34:21Z						biological_process											owl:Class	
GO:0060730	biolink:NamedThing	regulation of intestinal epithelial structure maintenance	Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.	got7fsn_ti							dph	2009-06-12T01:49:34Z						biological_process											owl:Class	
GO:2000844	biolink:NamedThing	negative regulation of testosterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.	got7fsn_ti							bf	2011-07-26T08:42:33Z						biological_process											owl:Class	
GO:0019386	biolink:NamedThing	methanogenesis, from carbon dioxide	The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2).	got7fsn_ti	methane biosynthesis from carbon dioxide|methane biosynthetic process from carbon dioxide											MetaCyc:METHANOGENESIS-PWY		biological_process											owl:Class	
GO:0060501	biolink:NamedThing	positive regulation of epithelial cell proliferation involved in lung morphogenesis	Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.	got7fsn_ti														biological_process											owl:Class	
GO:0016582	biolink:NamedThing	obsolete non-covalent chromatin modification	OBSOLETE. The alteration of DNA or protein in chromatin by the non-covalent addition or removal of chemical groups.	got7fsn_ti					This term was made obsolete because it was added in error; its usefulness is unclear.					True				biological_process											owl:Class	
GO:0033046	biolink:NamedThing	negative regulation of sister chromatid segregation	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.	got7fsn_ti														biological_process											owl:Class	
GO:0030482	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:15372	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16907	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005096	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0080003	biolink:NamedThing	thalianol metabolic process	The chemical reactions and pathways involving the triterpene thalianol.	got7fsn_ti	thalianol metabolism													biological_process											owl:Class	
UBERON:0002329	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001182	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075260	biolink:NamedThing	regulation of spore-bearing organ development	Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.	got7fsn_ti														biological_process											owl:Class	
GO:0016511	biolink:NamedThing	obsolete endothelin-converting enzyme activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	endothelin-converting enzyme activity			GO:0004222	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:2000348	biolink:NamedThing	regulation of CD40 signaling pathway	Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.	got7fsn_ti	regulation of CD40 signalling pathway						mah	2011-02-03T10:29:40Z						biological_process											owl:Class	
GO:0060518	biolink:NamedThing	cell migration involved in prostatic bud elongation	The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud.	got7fsn_ti														biological_process											owl:Class	
GO:0052182	biolink:NamedThing	obsolete modification by host of symbiont morphology or physiology via secreted substance	OBSOLETE. The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by a substance secreted by one of the organisms. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
UBERON:0001007	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35406	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005969	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032897	biolink:NamedThing	negative regulation of viral transcription	Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.	got7fsn_ti	downregulation of viral transcription|inhibition of viral transcription|down-regulation of viral transcription|down regulation of viral transcription													biological_process											owl:Class	
GO:0042689	biolink:NamedThing	regulation of crystal cell differentiation	Any process that modulates the frequency, rate or extent of crystal cell differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0046188	biolink:NamedThing	methane catabolic process	The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.	got7fsn_ti	methane breakdown|methane degradation|methane catabolism													biological_process											owl:Class	
CL:0000632	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904122	biolink:NamedThing	positive regulation of fatty acid beta-oxidation by octopamine signaling pathway	An octopamine signaling pathway that results in positive regulation of fatty acid beta-oxidation.	got7fsn_ti	stimulation of fatty acid beta-oxidation by octopamine signaling pathway|up regulation of fatty acid beta-oxidation by octopamine signaling pathway|upregulation of fatty acid beta-oxidation by octopamine signaling pathway|activation of fatty acid beta-oxidation by octopamine signaling pathway|up-regulation of fatty acid beta-oxidation by octopamine signaling pathway						kmv	2015-04-08T21:03:13Z						biological_process											owl:Class	
GO:0009207	biolink:NamedThing	purine ribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.	got7fsn_ti	purine ribonucleoside triphosphate breakdown|purine ribonucleoside triphosphate catabolism|purine ribonucleoside triphosphate degradation													biological_process											owl:Class	
GO:1904355	biolink:NamedThing	positive regulation of telomere capping	Any process that activates or increases the frequency, rate or extent of telomere capping.	got7fsn_ti	up regulation of telomere capping|upregulation of telomere end protection|up regulation of telomere end protection|up-regulation of telomere capping|up-regulation of telomere end protection|upregulation of telomere capping|activation of telomere capping|positive regulation of telomere end protection|activation of telomere end protection						nc	2015-06-12T16:51:20Z						biological_process											owl:Class	
GO:1904552	biolink:NamedThing	regulation of chemotaxis to arachidonic acid	Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid.	got7fsn_ti							sl	2015-08-13T21:08:14Z						biological_process											owl:Class	
GO:0046648	biolink:NamedThing	positive regulation of gamma-delta T cell proliferation	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation.	got7fsn_ti	positive regulation of gamma-delta T lymphocyte proliferation|up-regulation of gamma-delta T cell proliferation|stimulation of gamma-delta T cell proliferation|positive regulation of gamma-delta T-cell proliferation|positive regulation of gamma-delta T-lymphocyte proliferation|upregulation of gamma-delta T cell proliferation|up regulation of gamma-delta T cell proliferation|activation of gamma-delta T cell proliferation													biological_process											owl:Class	
GO:0015973	biolink:NamedThing	guanosine pentaphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.	got7fsn_ti	guanosine pentaphosphate formation|guanosine pentaphosphate (5'-pppGpp-3') biosynthesis|guanosine pentaphosphate synthesis|guanosine pentaphosphate anabolism|guanosine pentaphosphate (5'-pppGpp-3') biosynthetic process|guanosine pentaphosphate biosynthesis													biological_process											owl:Class	
CHEBI:22605	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090350	biolink:NamedThing	negative regulation of cellular organofluorine metabolic process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.	got7fsn_ti							tb	2010-06-02T10:36:42Z						biological_process											owl:Class	
PR:000009799	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032562	biolink:NamedThing	dAMP binding	Binding to dAMP, deoxyadenosine monophosphate.	got7fsn_ti														molecular_function											owl:Class	
GO:0033524	biolink:NamedThing	sinapate ester metabolic process	The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.	got7fsn_ti	sinapate ester metabolism													biological_process											owl:Class	
GO:0001008	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:79202	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903242	biolink:NamedThing	regulation of cardiac muscle hypertrophy in response to stress	Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.	got7fsn_ti							rl	2014-08-01T16:31:36Z						biological_process											owl:Class	
GO:0001312	biolink:NamedThing	obsolete replication of extrachromosomal rDNA circles involved in replicative cell aging	OBSOLETE. Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication.	got7fsn_ti	replication of extrachromosomal ribosomal DNA circles during replicative cell aging|replication of extrachromosomal rDNA circles during replicative cell aging|replication of extrachromosomal rDNA circles during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007			This term was obsoleted because it represents an assay, not a true biological process.					True				biological_process											owl:Class	
GO:0086084	biolink:NamedThing	cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication	Binding to a protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells.	got7fsn_ti							dph	2011-11-22T11:13:16Z						molecular_function											owl:Class	
GO:1901632	biolink:NamedThing	regulation of synaptic vesicle membrane organization	Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization.	got7fsn_ti	regulation of SLMV biogenesis|regulation of synaptic vesicle membrane organisation|regulation of synaptic vesicle membrane organization and biogenesis						ans	2012-11-15T11:40:48Z						biological_process											owl:Class	
CHEBI:28506	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:84144	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990610	biolink:NamedThing	acetolactate synthase regulator activity	Binds to and modulates the activity of acetolactate synthase.	got7fsn_ti							vw	2015-01-20T12:54:43Z						molecular_function											owl:Class	
GO:0052238	biolink:NamedThing	obsolete aerotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	aerotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0060660	biolink:NamedThing	epidermis morphogenesis involved in nipple formation	The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.	got7fsn_ti							dph	2009-05-29T11:04:04Z						biological_process											owl:Class	
CHEBI:13705	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16374	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33216	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019321	biolink:NamedThing	pentose metabolic process	The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.	got7fsn_ti	pentose metabolism													biological_process											owl:Class	
GO:0009139	biolink:NamedThing	pyrimidine nucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine nucleoside diphosphate biosynthesis|pyrimidine nucleoside diphosphate formation|pyrimidine nucleoside diphosphate synthesis|pyrimidine nucleoside diphosphate anabolism													biological_process											owl:Class	
CHEBI:26271	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002511	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006502	biolink:NamedThing	obsolete C-terminal protein prenylation	OBSOLETE. The covalent or non-covalent attachment of a prenyl group to the carboxy-terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.	got7fsn_ti	C-terminal protein prenylation			GO:0018342	This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein.					True				biological_process											owl:Class	
GO:0008359	biolink:NamedThing	regulation of bicoid mRNA localization	Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.	got7fsn_ti	regulation of bicoid mRNA localisation													biological_process											owl:Class	
GO:0052212	biolink:NamedThing	obsolete modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by one of the organisms, where the two organisms are in a symbiotic interaction.	got7fsn_ti	modification of morphology or physiology of other organism via secreted substance during symbiotic interaction|modification of host morphology or physiology via ellicitor|modification of host morphology or physiology via effector molecule				This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True				biological_process											owl:Class	
UBERON:0000927	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000841	biolink:NamedThing	negative regulation of dehydroepiandrosterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion.	got7fsn_ti	negative regulation of dehydroisoandrosterone secretion|negative regulation of DHEA secretion|negative regulation of 3beta-hydroxyandrost-5-en-17-one secretion						bf	2011-07-26T08:41:33Z						biological_process											owl:Class	
GO:0046061	biolink:NamedThing	dATP catabolic process	The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).	got7fsn_ti	dATP degradation|dATP breakdown|dATP catabolism													biological_process											owl:Class	
GO:0010798	biolink:NamedThing	regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism	Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin.	got7fsn_ti														biological_process											owl:Class	
GO:0099062	biolink:NamedThing	integral component of postsynaptic early endosome membrane	The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0043279	biolink:NamedThing	response to alkaloid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.	got7fsn_ti														biological_process											owl:Class	
GO:0043627	biolink:NamedThing	response to estrogen	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.	got7fsn_ti	response to oestrogen stimulus|response to estrogen stimulus													biological_process											owl:Class	
CHEBI:27684	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071413	biolink:NamedThing	cellular response to hydroxyisoflavone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.	got7fsn_ti							mah	2009-12-14T03:10:09Z						biological_process											owl:Class	
PR:000012826	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072290	biolink:NamedThing	epithelial cell migration involved in metanephric nephron tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.	got7fsn_ti							mah	2010-04-09T03:52:29Z						biological_process											owl:Class	
GO:0044859	biolink:NamedThing	protein insertion into plasma membrane raft	The process in which a protein is incorporated into a plasma membrane raft.	got7fsn_ti							jl	2014-07-23T16:23:20Z						biological_process											owl:Class	
GO:0030467	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044216	biolink:NamedThing	obsolete other organism cell	OBSOLETE. A cell of a secondary organism with which the first organism is interacting.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19036|https://github.com/geneontology/go-ontology/issues/17394			This term was obsoleted because cell (and therefore 'other organism cell') was considered outside the scope of GO.		jl	2009-11-12T01:17:06Z		True				cellular_component											owl:Class	
PR:000009064	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:2001472	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60197	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010615	biolink:NamedThing	positive regulation of cardiac muscle adaptation	Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.	got7fsn_ti														biological_process											owl:Class	
GO:0046080	biolink:NamedThing	dUTP metabolic process	The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.	got7fsn_ti	dUTP metabolism													biological_process											owl:Class	
GO:0045031	biolink:NamedThing	G protein-coupled ATP receptor activity	Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	got7fsn_ti	ATP-activated adenosine receptor activity|ATP-activated nucleotide receptor activity													molecular_function											owl:Class	
GO:0010510	biolink:NamedThing	regulation of acetyl-CoA biosynthetic process from pyruvate	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.	got7fsn_ti														biological_process											owl:Class	
GO:0100001	biolink:NamedThing	regulation of skeletal muscle contraction by action potential	Any action potential process that regulates skeletal muscle contraction.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
UBERON:0004178	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17955	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046330	biolink:NamedThing	positive regulation of JNK cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.	got7fsn_ti	activation of JNK cascade|up-regulation of JNK cascade|up regulation of JNK cascade|upregulation of JNK cascade|stimulation of JNK cascade													biological_process											owl:Class	
CHEBI:31746	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904147	biolink:NamedThing	response to nonylphenol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.	got7fsn_ti							sl	2015-04-14T17:01:44Z						biological_process											owl:Class	
CHEBI:29991	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000907	biolink:NamedThing	negative regulation of glucomannan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process.	got7fsn_ti	negative regulation of glucomannan catabolism						tt	2011-07-29T01:13:24Z						biological_process											owl:Class	
GO:0019303	biolink:NamedThing	D-ribose catabolic process	The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).	got7fsn_ti	D-ribose degradation|D-ribose catabolism|D-ribose breakdown											MetaCyc:RIBOKIN-PWY		biological_process											owl:Class	
GO:0070099	biolink:NamedThing	regulation of chemokine-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.	got7fsn_ti	regulation of chemokine-mediated signalling pathway													biological_process											owl:Class	
GO:0097284	biolink:NamedThing	hepatocyte apoptotic process	Any apoptotic process in a hepatocyte, the main structural component of the liver.	got7fsn_ti	hepatocyte apoptosis						pr	2012-03-29T10:23:21Z						biological_process											owl:Class	
GO:0080025	biolink:NamedThing	phosphatidylinositol-3,5-bisphosphate binding	Binding to phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.	got7fsn_ti	PtdIns(3,5)P2 binding													molecular_function											owl:Class	
CHEBI:57694	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031599	biolink:NamedThing	obsolete ER proteasome regulatory particle	OBSOLETE. The regulatory subcomplex of a proteasome located in the endoplasmic reticulum of a cell.	got7fsn_ti					This term was made obsolete because there is no evidence in the literature of its existence.					True				cellular_component											owl:Class	
CHEBI:16516	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075304	biolink:NamedThing	negative regulation of basidiospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.	got7fsn_ti														biological_process											owl:Class	
CL:0000575	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000035	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002735	biolink:NamedThing	positive regulation of myeloid dendritic cell cytokine production	Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.	got7fsn_ti	upregulation of myeloid dendritic cell cytokine production|stimulation of myeloid dendritic cell cytokine production|activation of myeloid dendritic cell cytokine production|up regulation of myeloid dendritic cell cytokine production|up-regulation of myeloid dendritic cell cytokine production													biological_process											owl:Class	
GO:0015033	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0018933	biolink:NamedThing	nicotine metabolic process	The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.	got7fsn_ti	nicotine metabolism													biological_process											owl:Class	
GO:1901742	biolink:NamedThing	2-deoxystreptamine metabolic process	The chemical reactions and pathways involving 2-deoxystreptamine.	got7fsn_ti	2-deoxystreptamine metabolism						yaf	2013-01-14T10:01:57Z						biological_process											owl:Class	
GO:1900529	biolink:NamedThing	obsolete regulation of cell shape involved in cellular response to glucose starvation	OBSOLETE. Any regulation of cell shape that is involved in cellular response to glucose starvation.	got7fsn_ti	regulation of cell shape involved in cellular response to glucose starvation				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2012-05-08T01:43:38Z		True				biological_process											owl:Class	
CHEBI:16646	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046704	biolink:NamedThing	CDP metabolic process	The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate.	got7fsn_ti	CDP metabolism													biological_process											owl:Class	
GO:0075010	biolink:NamedThing	regulation of germ tube formation	Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
UBERON:0005103	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26390	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051547	biolink:NamedThing	regulation of keratinocyte migration	Any process that modulates the frequency, rate or extent of keratinocyte migration.	got7fsn_ti														biological_process											owl:Class	
GO:0018338	biolink:NamedThing	obsolete protein amino acid cinnamylation	OBSOLETE. The modification of a protein amino acid by cinnamylation.	got7fsn_ti	protein amino acid cinnamylation				This term was made obsolete because it was an unnecessary grouping term.	GO:0018097				True				biological_process											owl:Class	
CHEBI:64492	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24599	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0062164	biolink:NamedThing	regulation of pseudohyphal septin ring assembly	Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly.	got7fsn_ti							dph	2019-11-07T15:52:20Z						biological_process											owl:Class	
GO:0034132	biolink:NamedThing	negative regulation of toll-like receptor 1 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 1 signalling pathway|negative regulation of TLR1 signaling pathway													biological_process											owl:Class	
GO:0002761	biolink:NamedThing	regulation of myeloid leukocyte differentiation	Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.	got7fsn_ti														biological_process											owl:Class	
GO:0048376	biolink:NamedThing	positive regulation of lateral mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination.	got7fsn_ti	positive regulation of lateral plate mesodermal cell fate determination|upregulation of lateral mesodermal cell fate determination|activation of lateral mesodermal cell fate determination|up regulation of lateral mesodermal cell fate determination|up-regulation of lateral mesodermal cell fate determination|stimulation of lateral mesodermal cell fate determination													biological_process											owl:Class	
GO:0032013	biolink:NamedThing	negative regulation of ARF protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.	got7fsn_ti	down-regulation of ARF protein signal transduction|downregulation of ARF protein signal transduction|inhibition of ARF protein signal transduction|down regulation of ARF protein signal transduction													biological_process											owl:Class	
GO:0008947	biolink:NamedThing	obsolete omptin activity	OBSOLETE. Catalysis of the preferential cleavage of Xaa-Yaa in which both Xaa and Yaa are Arg or Lys.	got7fsn_ti	omptin activity			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0034148	biolink:NamedThing	negative regulation of toll-like receptor 5 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.	got7fsn_ti	negative regulation of toll-like receptor 5 signalling pathway|negative regulation of TLR5 signaling pathway													biological_process											owl:Class	
GO:0016329	biolink:NamedThing	obsolete apoptosis regulator activity	OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis.	got7fsn_ti	apoptosis regulator activity			GO:0042981	This term was made obsolete because it represents involvement in a biological process.					True				molecular_function											owl:Class	
GO:0019557	biolink:NamedThing	histidine catabolic process to glutamate and formate	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate.	got7fsn_ti	histidine degradation to glutamate and formate|histidine breakdown to glutamate and formate													biological_process											owl:Class	
UBERON:0005113	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044214	biolink:NamedThing	spanning component of plasma membrane	The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.	got7fsn_ti	fully spanning plasma membrane|transmembrane				Proteins that span the membrane but have the bulk on one side of the membrane may be additionally annotated with a term of the form integral to X side of the plasma membrane.		jl	2009-11-04T01:50:57Z						cellular_component											owl:Class	
GO:0007081	biolink:NamedThing	obsolete mitotic sister-chromatid adhesion release	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	mitotic sister-chromatid adhesion release				This term was made obsolete because the term name is ambiguous and appears to encompass two processes.	GO:0000070|GO:0007064				True				biological_process											owl:Class	
GO:1904404	biolink:NamedThing	response to formaldehyde	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.	got7fsn_ti							sl	2015-06-23T21:14:04Z						biological_process											owl:Class	
CHEBI:26605	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098888	biolink:NamedThing	extrinsic component of presynaptic membrane	The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	got7fsn_ti	extrinsic component of presynaptic plasma membrane													cellular_component											owl:Class	
GO:0047764	biolink:NamedThing	obsolete caldesmon kinase activity	OBSOLETE. Catalysis of the reaction: ATP + caldesmon = ADP + caldesmon phosphate.	got7fsn_ti					This term was made obsolete because it represents a specific gene product.					True		MetaCyc:2.7.11.17-RXN		molecular_function											owl:Class	
GO:0072418	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075324	biolink:NamedThing	negative regulation of oomycete sporangium development	Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.	got7fsn_ti														biological_process											owl:Class	
CHEBI:16962	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031166	biolink:NamedThing	integral component of vacuolar membrane	The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.	got7fsn_ti	integral to vacuolar membrane													cellular_component											owl:Class	
GO:1903640	biolink:NamedThing	negative regulation of gastrin-induced gastric acid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion.	got7fsn_ti	down-regulation of gastrin-induced gastric acid secretion|inhibition of gastrin-induced gastric acid secretion|downregulation of gastrin-induced gastric acid secretion|down regulation of gastrin-induced gastric acid secretion						sl	2014-11-20T20:54:28Z						biological_process											owl:Class	
UBERON:0000203	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060283	biolink:NamedThing	negative regulation of oocyte development	Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	got7fsn_ti														biological_process											owl:Class	
GO:0048089	biolink:NamedThing	regulation of female pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females.	got7fsn_ti														biological_process											owl:Class	
GO:0032520	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016253	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015657	biolink:NamedThing	branched-chain amino acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).	got7fsn_ti														molecular_function											owl:Class	
PO:0020102	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63527	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032547	biolink:NamedThing	purine deoxyribonucleoside binding	Binding to a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.	got7fsn_ti														molecular_function											owl:Class	
GO:0048349	biolink:NamedThing	regulation of paraxial mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification.	got7fsn_ti														biological_process											owl:Class	
GO:0100011	biolink:NamedThing	positive regulation of fever generation by prostaglandin secretion	Any prostaglandin secretion process that positively_regulates fever generation.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
GO:0048261	biolink:NamedThing	negative regulation of receptor-mediated endocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.	got7fsn_ti	negative regulation of receptor mediated endocytosis|inhibition of receptor mediated endocytosis|down regulation of receptor mediated endocytosis|down-regulation of receptor mediated endocytosis|downregulation of receptor mediated endocytosis													biological_process											owl:Class	
GO:0060725	biolink:NamedThing	regulation of coreceptor activity	Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.	got7fsn_ti							dph	2009-06-12T01:20:11Z						biological_process											owl:Class	
GO:1904856	biolink:NamedThing	cytolytic granule lumen	Any cytoplasmic membrane-bounded vesicle lumen that is part of a cytolytic granule.	got7fsn_ti	cytoplasmic membrane-bounded vesicle lumen of cytolytic granule|cytoplasmic membrane-enclosed vesicle lumen of cytolytic granule|cytolytic granule cytoplasmic membrane-bounded vesicle lumen						mec	2015-12-15T12:51:17Z						cellular_component											owl:Class	
GO:1903827	biolink:NamedThing	regulation of cellular protein localization	Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.	got7fsn_ti	regulation of cellular protein localisation|regulation of channel localizer activity						jl	2015-01-20T14:32:14Z						biological_process											owl:Class	
GO:0016214	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1900406	biolink:NamedThing	obsolete regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of conjugation with cellular fusion.	got7fsn_ti					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T02:46:24Z		True				biological_process											owl:Class	
GO:0033293	biolink:NamedThing	monocarboxylic acid binding	Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).	got7fsn_ti														molecular_function											owl:Class	
GO:0046117	biolink:NamedThing	queuosine catabolic process	The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.	got7fsn_ti	queuosine catabolism|queuosine degradation|queuosine breakdown													biological_process											owl:Class	
OBO:OBA_0000141	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004162	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003161	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901682	biolink:NamedThing	sulfur compound transmembrane transporter activity	Enables the transfer of a sulfur compound from one side of a membrane to the other.	got7fsn_ti	sulfur molecular entity transmembrane transporter activity						pr	2012-11-26T20:45:29Z						molecular_function											owl:Class	
GO:0004981	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061887	biolink:NamedThing	obsolete reproduction of symbiont in host	OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms, occurring within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represents a process and a component.		dph	2017-06-01T18:07:47Z		True				biological_process											owl:Class	
UBERON:0001874	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002196	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006707	biolink:NamedThing	cholesterol catabolic process	The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti	cholesterol breakdown|cholesterol catabolism|cholesterol degradation													biological_process											owl:Class	
GO:1901790	biolink:NamedThing	3-(2,3-dihydroxyphenyl)propanoate metabolic process	The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate.	got7fsn_ti	3-(2,3-dihydroxyphenyl)propanoate metabolism						yaf	2013-01-16T11:40:57Z						biological_process											owl:Class	
GO:0015378	biolink:NamedThing	sodium:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in).	got7fsn_ti												Reactome:R-HSA-426130|Reactome:R-HSA-5623705		molecular_function											owl:Class	
GO:1904238	biolink:NamedThing	pericyte cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell.	got7fsn_ti							dph	2015-05-15T14:50:13Z						biological_process											owl:Class	
OBO:GOCHE_37527	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000189	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030376	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035953	biolink:NamedThing	obsolete regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of dipeptide transport, by regulation of transcription from an RNA polymerase II promoter.	got7fsn_ti	regulation of dipeptide transport by regulation of transcription from Pol II promoter				This term was obsoleted because it represents a GO-CAM model.		bf			True				biological_process											owl:Class	
GO:0014803	biolink:NamedThing	longitudinal sarcoplasmic reticulum lumen	The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae.	got7fsn_ti														cellular_component											owl:Class	
GO:0140201	biolink:NamedThing	urea import across plasma membrane	The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-02-20T10:15:45Z						biological_process											owl:Class	
GO:1900265	biolink:NamedThing	regulation of substance P receptor binding	Any process that modulates the frequency, rate or extent of substance P receptor binding.	got7fsn_ti	regulation of substance P receptor ligand|regulation of neurokinin-1 receptor binding						tb	2012-04-03T11:11:27Z						biological_process											owl:Class	
GO:1905038	biolink:NamedThing	regulation of membrane lipid metabolic process	Any process that modulates the frequency, rate or extent of membrane lipid metabolic process.	got7fsn_ti	regulation of membrane lipid metabolism						tb	2016-03-08T20:41:32Z						biological_process											owl:Class	
PR:000025845	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0001001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090401	biolink:NamedThing	obsolete viral-induced premature senescence	OBSOLETE. A cellular senescence process associated with the dismantling of a cell as a response to viral infection.	got7fsn_ti					The reason for obsoletion is was not clearly defined. There is nothing in the literature that mentions this process; there are papers that mention viral proteins overcoming premature senescence, for example, PMID:22326283.		tb	2011-01-05T02:37:57Z		True				biological_process											owl:Class	
GO:0033295	biolink:NamedThing	hydroxyectoine binding	Binding to hydroxyectoine.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:64514	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014071	biolink:NamedThing	response to cycloalkane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.	got7fsn_ti														biological_process											owl:Class	
GO:0017049	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003917	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016957	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006636	biolink:NamedThing	unsaturated fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.	got7fsn_ti	polyunsaturated fatty acid biosynthesis|unsaturated fatty acid anabolism|unsaturated fatty acid synthesis|unsaturated fatty acid biosynthesis|unsaturated fatty acid formation|fatty acid desaturation											MetaCyc:PWY-782|MetaCyc:PWY-762		biological_process											owl:Class	
GO:0051416	biolink:NamedThing	obsolete myotilin binding	OBSOLETE. Binding to myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C.	got7fsn_ti	myotilin binding			GO:0008092	This term was made obsolete because it represents binding to an individual protein.					True				molecular_function											owl:Class	
GO:1905651	biolink:NamedThing	regulation of artery morphogenesis	Any process that modulates the frequency, rate or extent of artery morphogenesis.	got7fsn_ti	regulation of arteriogenesis|regulation of arterial morphogenesis						rph	2016-11-09T12:19:37Z						biological_process											owl:Class	
UBERON:0005135	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010827	biolink:NamedThing	regulation of glucose transmembrane transport	Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of glucose transport													biological_process											owl:Class	
CHEBI:17266	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905235	biolink:NamedThing	response to quercetin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.	got7fsn_ti							sl	2016-06-07T21:29:40Z						biological_process											owl:Class	
CHEBI:27642	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052136	biolink:NamedThing	obsolete negative chemotaxis on or near host	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0075166	biolink:NamedThing	obsolete positive regulation of G-protein gamma subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
GO:1901266	biolink:NamedThing	cephalosporin C metabolic process	The chemical reactions and pathways involving cephalosporin C.	got7fsn_ti	cephalosporin C metabolism						yaf	2012-08-17T14:25:59Z						biological_process											owl:Class	
GO:0010694	biolink:NamedThing	positive regulation of alkaline phosphatase activity	Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.	got7fsn_ti														biological_process											owl:Class	
GO:1904555	biolink:NamedThing	L-proline transmembrane transport	The directed movement of L-proline across a membrane.	got7fsn_ti							pr	2015-08-14T14:21:06Z						biological_process											owl:Class	
GO:0061467	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000123	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016240	biolink:NamedThing	autophagosome membrane docking	The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.	got7fsn_ti	autophagic vacuole docking													biological_process											owl:Class	
GO:0030806	biolink:NamedThing	obsolete negative regulation of cyclic nucleotide catabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.	got7fsn_ti	negative regulation of cyclic nucleotide breakdown|downregulation of cyclic nucleotide catabolic process|down regulation of cyclic nucleotide catabolic process|down-regulation of cyclic nucleotide catabolic process|negative regulation of cyclic nucleotide catabolism|inhibition of cyclic nucleotide catabolic process|negative regulation of cyclic nucleotide degradation				The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True				biological_process											owl:Class	
GO:0001722	biolink:NamedThing	obsolete type I intermediate filament associated protein	OBSOLETE. Low molecular weight (10-45 kDa) proteins that associate with intermediate filaments by lateral binding of the filaments and have the effect of creating tight macrofilament aggregates.	got7fsn_ti	type I intermediate filament associated protein			GO:0005882	This term was made obsolete because it represents a single gene product and not a complex.					True				cellular_component											owl:Class	
GO:0070910	biolink:NamedThing	cell wall macromolecule catabolic process involved in cell wall disassembly	The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.	got7fsn_ti							mah	2009-09-09T02:40:57Z						biological_process											owl:Class	
CHEBI:58252	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16813	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000167	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045409	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034465	biolink:NamedThing	response to carbon monoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.	got7fsn_ti														biological_process											owl:Class	
CL:0000792	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28386	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019523	biolink:NamedThing	L-idonate metabolic process	The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	got7fsn_ti	L-idonate metabolism											MetaCyc:IDNCAT-PWY		biological_process											owl:Class	
GO:0007037	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0033479	biolink:NamedThing	UDP-D-galacturonate metabolic process	The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.	got7fsn_ti	UDP-D-galacturonate metabolism													biological_process											owl:Class	
CHEBI:17187	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0110109	biolink:NamedThing	negative regulation of imaginal disc-derived wing vein specification	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification.	got7fsn_ti							kmv	2018-07-05T13:55:37Z						biological_process											owl:Class	
CHEBI:35862	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002038	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007050	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:46574	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015529	biolink:NamedThing	raffinose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in).	got7fsn_ti	raffinose:hydrogen symporter activity													molecular_function											owl:Class	
GO:1904614	biolink:NamedThing	response to biphenyl	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.	got7fsn_ti							sl	2015-08-27T19:08:43Z						biological_process											owl:Class	
SO:0000862	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060046	biolink:NamedThing	regulation of acrosome reaction	Any process that modulates the frequency, rate or extent of the acrosome reaction.	got7fsn_ti														biological_process											owl:Class	
GO:1902000	biolink:NamedThing	homogentisate catabolic process	The chemical reactions and pathways resulting in the breakdown of homogentisate.	got7fsn_ti	homogentisate catabolism|homogentisate breakdown|homogentisate degradation						tb	2013-03-21T00:01:12Z						biological_process											owl:Class	
GO:0140205	biolink:NamedThing	oligopeptide import across plasma membrane	The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-02-22T15:48:21Z						biological_process											owl:Class	
GO:0045667	biolink:NamedThing	regulation of osteoblast differentiation	Any process that modulates the frequency, rate or extent of osteoblast differentiation.	got7fsn_ti														biological_process											owl:Class	
CHEBI:16827	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032366	biolink:NamedThing	intracellular sterol transport	The directed movement of sterols within cells.	got7fsn_ti														biological_process											owl:Class	
GO:0048062	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001396	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002285	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140505	biolink:NamedThing	regulation of microlipophagy	Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19869					pg	2020-08-14T12:56:29Z						biological_process											owl:Class	
CHEBI:23044	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046121	biolink:NamedThing	deoxyribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	got7fsn_ti	deoxyribonucleoside degradation|deoxyribonucleoside breakdown|deoxyribonucleoside catabolism													biological_process											owl:Class	
GO:0044830	biolink:NamedThing	modulation by host of viral RNA genome replication	A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication.	got7fsn_ti	regulation by host of viral RNA genome replication						jl	2014-02-06T11:43:16Z						biological_process											owl:Class	
GO:0045369	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:2001314	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15358	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:41218	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018976	biolink:NamedThing	1,2,3-tribromopropane metabolic process	The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture.	got7fsn_ti	1,2,3-tribromopropane metabolism											UM-BBD_pathwayID:tbp		biological_process											owl:Class	
GO:0060161	biolink:NamedThing	positive regulation of dopamine receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.	got7fsn_ti	positive regulation of dopamine receptor signalling pathway													biological_process											owl:Class	
PR:000004580	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031008	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000289	biolink:NamedThing	regulation of photoreceptor cell axon guidance	Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance.	got7fsn_ti	regulation of photoreceptor cell axon pathfinding						mah	2010-12-17T10:04:35Z						biological_process											owl:Class	
UBERON:0003064	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004356	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098899	biolink:NamedThing	spine apparatus lumen	The volume enclosed by the spine apparatus membrane.	got7fsn_ti														cellular_component											owl:Class	
GO:0008991	biolink:NamedThing	obsolete serine-type signal peptidase activity	OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by a serine endopeptidase mechanism.	got7fsn_ti	serine-type signal peptidase activity			GO:0004252	This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products.					True				molecular_function											owl:Class	
GO:0019457	biolink:NamedThing	methionine catabolic process to succinyl-CoA	The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA.	got7fsn_ti	methionine degradation to succinyl-CoA|methionine breakdown to succinyl-CoA											MetaCyc:METHIONINE-DEG1-PWY		biological_process											owl:Class	
GO:0019846	biolink:NamedThing	obsolete enterotoxin activity	OBSOLETE. Acts as to cause injury to the intestinal mucosa of other living organisms.	got7fsn_ti	enterotoxin activity				This term was made obsolete because it represents a class of gene products.	GO:0090729				True				molecular_function											owl:Class	
GO:0007550	biolink:NamedThing	obsolete establishment of dosage compensation	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	establishment of dosage compensation				This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms.	GO:0007549				True				biological_process											owl:Class	
CHEBI:27881	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052015	biolink:NamedThing	obsolete catabolism by symbiont of host carbohydrate	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	catabolism by organism of host carbohydrate	https://github.com/geneontology/go-ontology/issues/21469			This term was obsoleted because it represents a molecular function.					True				biological_process											owl:Class	
UBERON:0001650	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002154	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042905	biolink:NamedThing	9-cis-retinoic acid metabolic process	The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative.	got7fsn_ti	9-cis-retinoic acid metabolism													biological_process											owl:Class	
CHEBI:25710	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010911	biolink:NamedThing	regulation of isomerase activity	Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.	got7fsn_ti														biological_process											owl:Class	
GO:0005480	biolink:NamedThing	obsolete vesicle transport	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	vesicle transport			GO:0016192	This term was made obsolete because it represents a biological process and not a molecular function.					True				molecular_function											owl:Class	
GO:1901591	biolink:NamedThing	regulation of double-strand break repair via break-induced replication	Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication.	got7fsn_ti							al	2012-11-07T16:37:34Z						biological_process											owl:Class	
CHEBI:28107	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:65037	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018790	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902587	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0002387	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048073	biolink:NamedThing	regulation of eye pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:1900334	biolink:NamedThing	negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.	got7fsn_ti	down regulation of methane biosynthetic process from 3-(methylthio)propionic acid|down-regulation of methane biosynthetic process from 3-(methylthio)propionic acid|downregulation of methane biosynthetic process from 3-(methylthio)propionic acid|inhibition of methane biosynthetic process from 3-(methylthio)propionic acid						tt	2012-04-06T01:56:23Z						biological_process											owl:Class	
GO:0090340	biolink:NamedThing	positive regulation of secretion of lysosomal enzymes	Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.	got7fsn_ti							tb	2010-06-01T03:35:57Z						biological_process											owl:Class	
GO:0035548	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015913	biolink:NamedThing	short-chain fatty acid import	The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6.	got7fsn_ti	short-chain fatty acid uptake													biological_process											owl:Class	
GO:0051513	biolink:NamedThing	regulation of monopolar cell growth	Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.	got7fsn_ti														biological_process											owl:Class	
GO:2001300	biolink:NamedThing	lipoxin metabolic process	The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.	got7fsn_ti	lipoxin metabolism						bf	2012-03-07T11:11:08Z						biological_process											owl:Class	
GO:2000758	biolink:NamedThing	positive regulation of peptidyl-lysine acetylation	Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation.	got7fsn_ti							yaf	2011-06-16T09:51:35Z						biological_process											owl:Class	
GO:0032970	biolink:NamedThing	regulation of actin filament-based process	Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.	got7fsn_ti														biological_process											owl:Class	
CHEBI:57547	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58448	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018224	biolink:NamedThing			got7fsn_ti										True															owl:Class	
SO:0002140	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:53390	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901184	biolink:NamedThing	regulation of ERBB signaling pathway	Any process that modulates the frequency, rate or extent of ERBB signaling pathway.	got7fsn_ti	regulation of ErbB signaling|regulation of EGF receptor family signaling pathway|regulation of EGFR family signaling pathway|regulation of ERBB signalling pathway						rl	2012-07-24T07:37:11Z						biological_process											owl:Class	
GO:0004927	biolink:NamedThing	obsolete sevenless receptor activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	sevenless receptor activity				This term was made obsolete because it represents a gene product rather than an activity.	GO:0004888|GO:0008288|GO:0004714				True				molecular_function											owl:Class	
GO:0097332	biolink:NamedThing	response to antipsychotic drug	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.	got7fsn_ti							pr	2012-06-12T10:58:13Z						biological_process											owl:Class	
GO:0006411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0110097	biolink:NamedThing	regulation of calcium import into the mitochondrion	Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion.	got7fsn_ti							kmv	2018-02-28T00:33:51Z						biological_process											owl:Class	
UBERON:0003074	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044276	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902005	biolink:NamedThing	regulation of proline biosynthetic process	Any process that modulates the frequency, rate or extent of proline biosynthetic process.	got7fsn_ti	regulation of proline synthesis|regulation of proline anabolism|regulation of proline formation|regulation of proline biosynthesis						tb	2013-03-21T21:48:07Z						biological_process											owl:Class	
GO:0048846	biolink:NamedThing	axon extension involved in axon guidance	The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.	got7fsn_ti														biological_process											owl:Class	
GO:2001176	biolink:NamedThing	regulation of mediator complex assembly	Any process that modulates the frequency, rate or extent of mediator complex assembly.	got7fsn_ti							yaf	2011-11-02T11:22:18Z						biological_process											owl:Class	
GO:0070542	biolink:NamedThing	response to fatty acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0006307	biolink:NamedThing	DNA dealkylation involved in DNA repair	The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT).	got7fsn_ti														biological_process											owl:Class	
GO:1900291	biolink:NamedThing	regulation of galactotriose transport	Any process that modulates the frequency, rate or extent of galactotriose transport.	got7fsn_ti							tt	2012-04-05T07:25:58Z						biological_process											owl:Class	
GO:0034034	biolink:NamedThing	purine nucleoside bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	got7fsn_ti	purine nucleoside bisphosphate catabolism|purine nucleoside bisphosphate breakdown|purine nucleoside bisphosphate degradation													biological_process											owl:Class	
GO:0090041	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:17309	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001373	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046298	biolink:NamedThing	2,4-dichlorobenzoate catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).	got7fsn_ti	2,4-dichlorobenzoate degradation|2,4-dichlorobenzoate breakdown|2,4-dichlorobenzoate catabolism													biological_process											owl:Class	
GO:0003685	biolink:NamedThing	obsolete DNA repair protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	DNA repair protein				This term was made obsolete because it includes a process term.	GO:0003684				True				molecular_function											owl:Class	
GO:0051870	biolink:NamedThing	methotrexate binding	Binding to methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.	got7fsn_ti														molecular_function											owl:Class	
GO:0030393	biolink:NamedThing	fructoselysine metabolic process	The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.	got7fsn_ti	fructoselysine metabolism													biological_process											owl:Class	
GO:0033582	biolink:NamedThing	protein galactosylation in cytosol	The addition of a galactose unit to a protein amino acid in the cytosol.	got7fsn_ti	protein amino acid galactosylation in cytosol													biological_process											owl:Class	
GO:0048693	biolink:NamedThing	regulation of collateral sprouting of injured axon	Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon.	got7fsn_ti														biological_process											owl:Class	
GO:0014747	biolink:NamedThing	positive regulation of tonic skeletal muscle contraction	Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction.	got7fsn_ti														biological_process											owl:Class	
CHEBI:58595	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905657	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006698	biolink:NamedThing	obsolete ecdysone modification	OBSOLETE. The covalent or conformational alteration of ecdysone, resulting in a change in its properties.	got7fsn_ti	ecdysone modification			GO:0004501	This term was made obsolete because it was created to cover the conversion of ecdysone to its active form ecdysterone (20-hydroxyecdysone), but this reaction is carried out in a single step by ecdysone 20-monooxygenase (EC:1.14.99.22) and so is a function rather than a process.					True				biological_process											owl:Class	
GO:1990852	biolink:NamedThing	protein transport along microtubule to spindle pole body	The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins.	got7fsn_ti							vw	2015-09-15T11:09:54Z						biological_process											owl:Class	
GO:1903964	biolink:NamedThing	monounsaturated fatty acid metabolic process	The chemical reactions and pathways involving monounsaturated fatty acid.	got7fsn_ti	monounsaturated fatty acid metabolism				For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast.		pr	2015-02-25T20:35:48Z						biological_process											owl:Class	
CHEBI:24921	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000737	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002275	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031405	biolink:NamedThing	lipoic acid binding	Binding to lipoic acid, 1,2-dithiolane-3-pentanoic acid.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:21732	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009278	biolink:NamedThing	obsolete murein sacculus	OBSOLETE. A peptidoglycan polymer that forms the shape-determining structure of the cell all of Gram-negative bacteria.	got7fsn_ti	murein sacculus				This term was made obsolete because it was defined inaccurately.	GO:0009276				True				cellular_component											owl:Class	
GO:1903499	biolink:NamedThing	regulation of mitotic actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly.	got7fsn_ti	regulation of mitotic cytokinesis, actomyosin contractile ring assembly|regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|regulation of contractile ring assembly involved in mitotic cytokinesis|regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis						pr	2014-09-30T10:13:50Z						biological_process											owl:Class	
GO:0002921	biolink:NamedThing	negative regulation of humoral immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.	got7fsn_ti	down-regulation of humoral immune response|downregulation of humoral immune response|down regulation of humoral immune response|inhibition of humoral immune response													biological_process											owl:Class	
GO:0050701	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042130	biolink:NamedThing	negative regulation of T cell proliferation	Any process that stops, prevents or reduces the rate or extent of T cell proliferation.	got7fsn_ti	inhibition of T cell proliferation|downregulation of T cell proliferation|down regulation of T cell proliferation|negative regulation of T lymphocyte proliferation|negative regulation of T-cell proliferation|down-regulation of T cell proliferation|negative regulation of T-lymphocyte proliferation													biological_process											owl:Class	
GO:1900985	biolink:NamedThing	vindoline biosynthetic process	The chemical reactions and pathways resulting in the formation of vindoline.	got7fsn_ti	vindoline biosynthesis|vindoline formation|vindoline synthesis|vindoline anabolism						yaf	2012-06-14T09:17:03Z						biological_process											owl:Class	
UBERON:0000007	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26775	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030443	biolink:NamedThing	obsolete nuclear translocation of MAPK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	nuclear translocation of MAPK during sporulation (sensu Fungi)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
CHEBI:58627	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015540	biolink:NamedThing	3-hydroxyphenyl propionate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).	got7fsn_ti	3-hydroxyphenyl propionate:hydrogen ion symporter activity|3-hydroxyphenyl propionate porter activity													molecular_function											owl:Class	
GO:0045319	biolink:NamedThing	obsolete SRP-independent cotranslational protein-membrane targeting, translocation	OBSOLETE. The process during cotranslational membrane targeting wherein proteins move across a membrane. This process is independent of SRP and signal recognition.	got7fsn_ti	SRP-independent cotranslational protein-membrane targeting, translocation|SRP-independent cotranslational membrane targeting, translocation				This term was made obsolete because there is no evidence for the existence of this process.					True				biological_process											owl:Class	
CHEBI:57959	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0017158	biolink:NamedThing	regulation of calcium ion-dependent exocytosis	Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis.	got7fsn_ti														biological_process											owl:Class	
GO:0140215	biolink:NamedThing	regulation of D-aspartate import across plasma membrane	Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15041					pg	2018-04-11T15:33:35Z						biological_process											owl:Class	
GO:0032954	biolink:NamedThing	regulation of cytokinetic process	Any process that modulates the frequency, rate or extent of a cytokinetic process.	got7fsn_ti														biological_process											owl:Class	
CHEBI:70778	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25713	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002481	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:114953	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16091	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0009200	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0007135	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903270	biolink:NamedThing	regulation of cytoplasmic translational elongation through polyproline stretches	Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.	got7fsn_ti							mcc	2014-08-08T14:53:59Z						biological_process											owl:Class	
GO:1905763	biolink:NamedThing	MTREC complex binding	Binding to a MTREC complex.	got7fsn_ti	Mtl1-Red1 core complex binding|NURS complex binding|PAXT complex binding	https://github.com/geneontology/go-ontology/issues/21207					mah	2016-12-15T15:49:02Z						molecular_function											owl:Class	
GO:0002293	biolink:NamedThing	alpha-beta T cell differentiation involved in immune response	The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	got7fsn_ti	alpha-beta T-lymphocyte differentiation during immune response|alpha-beta T cell development involved in immune response|alpha-beta T-cell differentiation during immune response|alpha-beta T cell differentiation during immune response|alpha-beta T lymphocyte differentiation during immune response				Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.									biological_process											owl:Class	
GO:0010013	biolink:NamedThing	N-1-naphthylphthalamic acid binding	Binding to N-1-naphthylphthalamic acid, an auxin transport inhibitor.	got7fsn_ti														molecular_function											owl:Class	
GO:1904017	biolink:NamedThing	cellular response to Thyroglobulin triiodothyronine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.	got7fsn_ti							sl	2015-03-06T19:34:13Z						biological_process											owl:Class	
GO:2000108	biolink:NamedThing	positive regulation of leukocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process.	got7fsn_ti	positive regulation of leukocyte apoptosis						mah	2010-09-15T01:42:12Z						biological_process											owl:Class	
GO:1904947	biolink:NamedThing	folate import into mitochondrion	The process in which folic acid is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti	folic acid import into mitochondrion						rph	2016-02-03T12:10:14Z						biological_process											owl:Class	
GO:0015764	biolink:NamedThing	N-acetylglucosamine transport	The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
CHEBI:41983	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009694	biolink:NamedThing	jasmonic acid metabolic process	The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid.	got7fsn_ti	jasmonic acid metabolism													biological_process											owl:Class	
GO:1903025	biolink:NamedThing	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.	got7fsn_ti							dph	2014-05-15T17:55:54Z						biological_process											owl:Class	
GO:0009284	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905705	biolink:NamedThing	cellular response to paclitaxel	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus.	got7fsn_ti							sl	2016-11-16T21:40:32Z						biological_process											owl:Class	
UBERON:0007100	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901141	biolink:NamedThing	regulation of lignin biosynthetic process	Any process that modulates the frequency, rate or extent of lignin biosynthetic process.	got7fsn_ti	regulation of lignin formation|regulation of lignin anabolism|regulation of lignin biosynthesis|regulation of lignin synthesis						tb	2012-07-12T09:53:09Z						biological_process											owl:Class	
GO:0045540	biolink:NamedThing	regulation of cholesterol biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.	got7fsn_ti	regulation of cholesterol biosynthesis|regulation of cholesterol anabolism|regulation of cholesterol synthesis|regulation of cholesterol formation													biological_process											owl:Class	
GO:0031743	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:49019	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060213	biolink:NamedThing	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.	got7fsn_ti	positive regulation of 3' to 5' mRNA deadenylation|positive regulation of nuclear mRNA poly(A) tail shortening|positive regulation of mRNA deadenylation													biological_process											owl:Class	
GO:0019721	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:62941	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009059	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010310	biolink:NamedThing	regulation of hydrogen peroxide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.	got7fsn_ti	regulation of hydrogen peroxide metabolism													biological_process											owl:Class	
GO:0050940	biolink:NamedThing	regulation of late stripe melanocyte differentiation	Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation.	got7fsn_ti	regulation of late stripe melanophore differentiation													biological_process											owl:Class	
UBERON:0001846	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0009847	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061994	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045387	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003258	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in endocardial precursor cell differentiation	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of an endocardial precursor cell.	got7fsn_ti							dph	2009-10-15T01:10:34Z						biological_process											owl:Class	
GO:0070731	biolink:NamedThing	cGMP transport	The directed movement of cyclic GMP (cGMP), into, out of or within a cell.	got7fsn_ti	cyclic GMP transport						mah	2009-06-17T04:40:27Z						biological_process											owl:Class	
GO:0035602	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.	got7fsn_ti	FGFR signaling pathway involved in negative regulation of apoptosis in bone marrow|fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptosis in bone marrow|fibroblast growth factor receptor signalling pathway involved in negative regulation of apoptotic process in bone marrow|fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow|FGF receptor signaling pathway involved in negative regulation of apoptosis in bone marrow						bf	2010-11-15T11:09:20Z						biological_process											owl:Class	
GO:0009198	biolink:NamedThing	pyrimidine deoxyribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	got7fsn_ti	pyrimidine deoxyribonucleoside diphosphate catabolism|pyrimidine deoxyribonucleoside diphosphate breakdown|pyrimidine deoxyribonucleoside diphosphate degradation													biological_process											owl:Class	
GO:0110125	biolink:NamedThing	negative regulation of myotube cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.	got7fsn_ti							kmv	2018-08-22T21:12:47Z						biological_process											owl:Class	
GO:1905340	biolink:NamedThing	regulation of protein localization to kinetochore	Any process that modulates the frequency, rate or extent of protein localization to kinetochore.	got7fsn_ti	regulation of protein localisation to kinetochore|regulation of condensin localization to kinetochore				Q9H211 in Human in PMID:22581055		es	2016-07-27T15:26:36Z						biological_process											owl:Class	
GO:0062030	biolink:NamedThing	negative regulation of stress granule assembly	Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.	got7fsn_ti							dph	2018-04-16T19:19:32Z						biological_process											owl:Class	
GO:0035981	biolink:NamedThing	tongue muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.	got7fsn_ti							bf	2011-08-22T01:35:16Z						biological_process											owl:Class	
CHEBI:64465	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045293	biolink:NamedThing	mRNA editing complex	A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes.	got7fsn_ti	editosome													cellular_component											owl:Class	
GO:0051846	biolink:NamedThing	obsolete active evasion of symbiont immune response	OBSOLETE. Any mechanism of immune avoidance that directly affects the symbiont immune system, e.g. blocking any stage in symbiont MHC class I and II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	active immune evasion|active evasion of symbiont immune response				This term was made obsolete because it does not represent a real process that exists in nature.					True				biological_process											owl:Class	
UBERON:0004170	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0005006	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031909	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019007	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098905	biolink:NamedThing	regulation of bundle of His cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	got7fsn_ti	regulation of bundle of His cardiac muscle cell action potential						dph	2011-11-15T12:01:18Z						biological_process											owl:Class	
GO:0008415	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:51143	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000016798	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002068	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045803	biolink:NamedThing	obsolete positive regulation of cytoskeleton	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton.	got7fsn_ti	positive regulation of cytoskeleton				This term was made obsolete because cytoskeleton is not a process, so the term made no sense.	GO:0007010				True				biological_process											owl:Class	
GO:0005501	biolink:NamedThing	retinoid binding	Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.	got7fsn_ti												Reactome:R-HSA-2454113|Reactome:R-HSA-2465934|Reactome:R-HSA-2464809|Reactome:R-HSA-2465938		molecular_function											owl:Class	
GO:0042521	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903959	biolink:NamedThing	regulation of anion transmembrane transport	Any process that modulates the frequency, rate or extent of anion transmembrane transport.	got7fsn_ti							pr	2015-02-25T13:52:25Z						biological_process											owl:Class	
GO:1902996	biolink:NamedThing	regulation of neurofibrillary tangle assembly	Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly.	got7fsn_ti	regulation of flame-shaped neurofibrillary tangle formation|regulation of neurofibrillary tangle formation|regulation of flame-shaped neurofibrillary tangle assembly|regulation of star-shaped neurofibrillary tangle formation|regulation of star-shaped neurofibrillary tangle assembly						sjp	2014-05-08T15:44:27Z						biological_process											owl:Class	
CL:0000762	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904904	biolink:NamedThing	regulation of endothelial cell-matrix adhesion via fibronectin	Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.	got7fsn_ti							bc	2016-01-19T10:23:01Z						biological_process											owl:Class	
GO:0099094	biolink:NamedThing	ligand-gated cation channel activity	Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	got7fsn_ti														molecular_function											owl:Class	
GO:1904822	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030527	biolink:NamedThing	structural constituent of chromatin	The action of a molecule that contributes to the structural integrity of chromatin.	got7fsn_ti														molecular_function											owl:Class	
PO:0009013	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034391	biolink:NamedThing	regulation of smooth muscle cell apoptotic process	Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.	got7fsn_ti	regulation of SMC apoptosis|regulation of smooth muscle cell apoptosis													biological_process											owl:Class	
GO:2000912	biolink:NamedThing	regulation of galactoglucomannan catabolic process	Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process.	got7fsn_ti	regulation of galactoglucomannan catabolism						tt	2011-07-29T07:51:31Z						biological_process											owl:Class	
GO:1905131	biolink:NamedThing	carcinine transmembrane transporter activity	Enables the transfer of carcinine from one side of a membrane to the other.	got7fsn_ti							dph	2016-04-12T15:18:25Z						molecular_function											owl:Class	
GO:1900211	biolink:NamedThing	regulation of mesenchymal cell apoptotic process involved in metanephros development	Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.	got7fsn_ti	regulation of mesenchymal cell apoptosis involved in metanephros development						yaf	2012-03-22T10:52:50Z						biological_process											owl:Class	
UBERON:0000304	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000089	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031274	biolink:NamedThing	positive regulation of pseudopodium assembly	Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.	got7fsn_ti	up regulation of pseudopodium formation|activation of pseudopodium formation|stimulation of pseudopodium formation|up-regulation of pseudopodium formation|positive regulation of pseudopodium formation|upregulation of pseudopodium formation													biological_process											owl:Class	
UBERON:0002094	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034049	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:37445	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006651	biolink:NamedThing	diacylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.	got7fsn_ti	diacylglycerol biosynthesis|diglyceride biosynthesis|diacylglycerol anabolism|diacylglycerol formation|diacylglycerol synthesis													biological_process											owl:Class	
GO:0033183	biolink:NamedThing	negative regulation of histone ubiquitination	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.	got7fsn_ti														biological_process											owl:Class	
UBERON:0001775	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903794	biolink:NamedThing	cortisol binding	Binding to cortisol.	got7fsn_ti							mr	2015-01-14T19:02:31Z						molecular_function											owl:Class	
GO:0031353	biolink:NamedThing	integral component of plastid inner membrane	The component of the plastid inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti	integral to plastid inner membrane													cellular_component											owl:Class	
GO:0051616	biolink:NamedThing	regulation of histamine uptake	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.	got7fsn_ti	regulation of histamine import													biological_process											owl:Class	
UBERON:0002080	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002523	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002649	biolink:NamedThing	regulation of tolerance induction to self antigen	Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.	got7fsn_ti														biological_process											owl:Class	
GO:0007025	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001285	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005718	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:18359	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034133	biolink:NamedThing	positive regulation of toll-like receptor 1 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.	got7fsn_ti	positive regulation of TLR1 signaling pathway|positive regulation of toll-like receptor 1 signalling pathway													biological_process											owl:Class	
CHEBI:25717	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000789	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098973	biolink:NamedThing	structural constituent of postsynaptic actin cytoskeleton	The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton.	got7fsn_ti														molecular_function											owl:Class	
GO:1902535	biolink:NamedThing	multi-organism membrane invagination	A membrane invagination which involves another organism.	got7fsn_ti							jl	2013-12-02T13:58:43Z						biological_process											owl:Class	
CL:0000793	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015357	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007102	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0035833	biolink:NamedThing	berbamunine biosynthetic process	The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid.	got7fsn_ti	berbamunine anabolism|berbamunine formation|berbamunine biosynthesis|berbamunine synthesis						bf	2011-05-04T03:12:03Z						biological_process											owl:Class	
GO:0006459	biolink:NamedThing	obsolete binding unfolded ER proteins	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	binding unfolded ER proteins				This term was made obsolete because it represents a function rather than a process.	GO:0005783|GO:0051082				True				biological_process											owl:Class	
CHEBI:47916	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64974	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060147	biolink:NamedThing	regulation of posttranscriptional gene silencing	Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.	got7fsn_ti														biological_process											owl:Class	
CHEBI:34687	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010238	biolink:NamedThing	response to proline	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0001871	biolink:NamedThing	obsolete pattern binding	OBSOLETE. Binding to a repeating or polymeric structure, such as a polysaccharide or peptidoglycan.	got7fsn_ti	pattern recognition activity				This term was obsoleted because it was an unnecessary grouping term.					True				molecular_function											owl:Class	
GO:0062068	biolink:NamedThing	chloroplast photosystem II binding	Binding to a chloroplast photosystem II.	got7fsn_ti							dph	2018-08-31T14:09:17Z						molecular_function											owl:Class	
GO:0009660	biolink:NamedThing	amyloplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch.	got7fsn_ti	amyloplast organization and biogenesis|amyloplast organisation													biological_process											owl:Class	
CHEBI:57572	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048409	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1901807	biolink:NamedThing	capsanthin metabolic process	The chemical reactions and pathways involving capsanthin.	got7fsn_ti	capsanthin metabolism						yaf	2013-01-22T10:21:39Z						biological_process											owl:Class	
GO:0031212	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010300	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0085027	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005382	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:18002	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990284	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019644	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0042971	biolink:NamedThing	obsolete lactone transmembrane transporter activity	OBSOLETE. Enables the transfer of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	got7fsn_ti					This term was obsoleted because there is no evidence for a specific lactone transporter.					True				molecular_function											owl:Class	
CL:1000413	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003906	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000469	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000766	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000010877	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37024	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57632	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099060	biolink:NamedThing	integral component of postsynaptic specialization membrane	The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	got7fsn_ti														cellular_component											owl:Class	
CHEBI:17833	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62537	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050897	biolink:NamedThing	cobalt ion binding	Binding to a cobalt ion (Co).	got7fsn_ti	Co ion binding|cobalt binding													molecular_function											owl:Class	
GO:1900892	biolink:NamedThing	positive regulation of pentadecane metabolic process	Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process.	got7fsn_ti	upregulation of pentadecane metabolism|positive regulation of pentadecane metabolism|up-regulation of pentadecane metabolism|activation of pentadecane metabolic process|up-regulation of pentadecane metabolic process|activation of pentadecane metabolism|upregulation of pentadecane metabolic process|up regulation of pentadecane metabolism|up regulation of pentadecane metabolic process						tt	2012-06-13T03:06:20Z						biological_process											owl:Class	
CL:0000486	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4705	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015907	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0007132	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008342	biolink:NamedThing	obsolete larval feeding behavior (sensu Insecta)	OBSOLETE. Feeding behavior in an insect larva.	got7fsn_ti	larval feeding behavior (sensu Insecta)			GO:0030536	This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term.					True				biological_process											owl:Class	
GO:0043546	biolink:NamedThing	molybdopterin cofactor binding	Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.	got7fsn_ti	Moco binding													molecular_function											owl:Class	
GO:0097034	biolink:NamedThing	obsolete mitochondrial respiratory chain complex IV biogenesis	OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase complex), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	got7fsn_ti	mitochondrial cytochrome c oxidase complex biogenesis	https://github.com/geneontology/go-ontology/issues/15173			The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		pr	2011-04-05T03:02:54Z		True				biological_process											owl:Class	
GO:2000281	biolink:NamedThing	regulation of histone H3-T3 phosphorylation	Any process that modulates the frequency, rate or extent of histone H3-T3 phosphorylation.	got7fsn_ti							vw	2010-12-10T11:48:31Z						biological_process											owl:Class	
CHEBI:139070	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033385	biolink:NamedThing	geranylgeranyl diphosphate metabolic process	The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins.	got7fsn_ti	geranylgeranyl diphosphate metabolism|geranylgeranyldiphosphate metabolic process													biological_process											owl:Class	
CHEBI:78697	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0007005	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120189	biolink:NamedThing	positive regulation of bile acid secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.	got7fsn_ti							krc	2018-07-16T22:36:17Z						biological_process											owl:Class	
GO:0120068	biolink:NamedThing	regulation of stomach fundus smooth muscle contraction	Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction.	got7fsn_ti							krc	2017-06-13T23:22:52Z						biological_process											owl:Class	
GO:0033127	biolink:NamedThing	regulation of histone phosphorylation	Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.	got7fsn_ti														biological_process											owl:Class	
GO:0060557	biolink:NamedThing	positive regulation of vitamin D biosynthetic process	Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	got7fsn_ti							dph	2009-04-13T02:46:14Z						biological_process											owl:Class	
CHEBI:61296	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0055053	biolink:NamedThing	mannose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+.	got7fsn_ti	mannose:hydrogen symporter activity													molecular_function											owl:Class	
owl:deprecated	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
CHEBI:33279	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28787	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090313	biolink:NamedThing	regulation of protein targeting to membrane	Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.	got7fsn_ti							tb	2010-04-16T03:42:22Z						biological_process											owl:Class	
GO:1904033	biolink:NamedThing	negative regulation of t-SNARE clustering	Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering.	got7fsn_ti	down-regulation of t-SNARE clustering|down regulation of t-SNARE clustering|downregulation of t-SNARE clustering|inhibition of t-SNARE clustering						sl	2015-03-13T21:21:44Z						biological_process											owl:Class	
CL:0000852	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043149	biolink:NamedThing	stress fiber assembly	The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.	got7fsn_ti	actin cable assembly|stress fibre biosynthesis|stress fibre formation|actin cable formation													biological_process											owl:Class	
CHEBI:133476	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0010136	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008646	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098724	biolink:NamedThing	symmetric stem cell division	Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population.	got7fsn_ti					Examples include the self-renewal of spermatogonial stem cells and (some) division during amplification of skeletal muscle satellite cell populations.									biological_process											owl:Class	
GO:0045609	biolink:NamedThing	positive regulation of inner ear auditory receptor cell differentiation	Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation.	got7fsn_ti	up regulation of auditory receptor cell differentiation|positive regulation of auditory hair cell differentiation|stimulation of auditory receptor cell differentiation|up-regulation of auditory receptor cell differentiation|activation of auditory receptor cell differentiation|positive regulation of auditory receptor cell differentiation|upregulation of auditory receptor cell differentiation													biological_process											owl:Class	
GO:0075092	biolink:NamedThing	obsolete negative regulation by host of symbiont signal transduction mediated by G-protein alpha subunit	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
GO:0019271	biolink:NamedThing	aerobactin transport	The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.	got7fsn_ti														biological_process											owl:Class	
GO:0090205	biolink:NamedThing	positive regulation of cholesterol metabolic process	Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	got7fsn_ti							tb	2009-12-23T10:27:37Z						biological_process											owl:Class	
CHEBI:36235	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903696	biolink:NamedThing	protein localization to horsetail-astral microtubule array	A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array.	got7fsn_ti	protein localisation to horsetail-astral microtubule array|protein localisation in horsetail-astral microtubule array|protein localization in horsetail-astral microtubule array						mah	2014-12-03T10:58:18Z						biological_process											owl:Class	
GO:0033395	biolink:NamedThing	beta-alanine biosynthetic process via 3-hydroxypropionate	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate.	got7fsn_ti	beta-alanine biosynthesis via 3-hydroxypropionate|beta-alanine anabolism via 3-hydroxypropionate|beta-alanine formation via 3-hydroxypropionate|beta-alanine synthesis via 3-hydroxypropionate											MetaCyc:PWY-3941		biological_process											owl:Class	
CHEBI:45804	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901308	biolink:NamedThing	regulation of sterol regulatory element binding protein cleavage	Any process that modulates the frequency, rate or extent of sterol regulatory element binding protein cleavage.	got7fsn_ti	regulation of SREBP cleavage						bf	2012-08-21T16:43:12Z						biological_process											owl:Class	
GO:0032434	biolink:NamedThing	regulation of proteasomal ubiquitin-dependent protein catabolic process	Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	got7fsn_ti														biological_process											owl:Class	
GO:0018910	biolink:NamedThing	benzene metabolic process	The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.	got7fsn_ti	benzene metabolism													biological_process											owl:Class	
GO:0010363	biolink:NamedThing	regulation of plant-type hypersensitive response	Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response.	got7fsn_ti	regulation of HR|regulation of HR-PCD|regulation of plant hypersensitive response				Note that term is to be used to annotate gene products in the plant. To annotate genes in a symbiont, consider the biological process term 'modulation by symbiont of host programmed cell death ; GO:0052040'.									biological_process											owl:Class	
GO:2001024	biolink:NamedThing	negative regulation of response to drug	Any process that stops, prevents or reduces the frequency, rate or extent of response to drug.	got7fsn_ti	negative regulation of drug resistance|negative regulation of drug susceptibility/resistance						yaf	2011-08-19T01:47:24Z						biological_process											owl:Class	
GO:0098525	biolink:NamedThing	excitatory neuromuscular junction of somatic myotube	A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells.	got7fsn_ti							dos	2013-10-14T12:06:08Z						cellular_component											owl:Class	
GO:1905236	biolink:NamedThing	cellular response to quercetin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.	got7fsn_ti							sl	2016-06-07T21:29:48Z						biological_process											owl:Class	
CHEBI:59338	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:85620	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000028269	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044756	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060268	biolink:NamedThing	negative regulation of respiratory burst	Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	got7fsn_ti														biological_process											owl:Class	
CHEBI:47778	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901161	biolink:NamedThing	primary amino compound catabolic process	The chemical reactions and pathways resulting in the breakdown of primary amino compound.	got7fsn_ti	primary amino compound degradation|primary amino compound catabolism|primary amino compound breakdown						bf	2012-07-18T04:45:06Z						biological_process											owl:Class	
CHEBI:2639	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019738	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:28757	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25609	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033170	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005523	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099043	biolink:NamedThing	cargo loading involved in clathrin-dependent endocytosis	Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat.	got7fsn_ti														biological_process											owl:Class	
GO:1990639	biolink:NamedThing	obsolete inositol-3,4,5-trisphosphate 5-phosphatase activity	OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4,5-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.	got7fsn_ti	inositol-3,4,5-trisphosphate 5-phosphatase activity				This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-02-11T15:58:56Z		True				molecular_function											owl:Class	
CHEBI:60173	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045575	biolink:NamedThing	basophil activation	The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors.	got7fsn_ti												Wikipedia:Basophil_activation		biological_process											owl:Class	
UBERON:0001264	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051107	biolink:NamedThing	negative regulation of DNA ligation	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.	got7fsn_ti	down regulation of DNA ligation|inhibition of DNA ligation|down-regulation of DNA ligation|downregulation of DNA ligation													biological_process											owl:Class	
CL:0011004	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900877	biolink:NamedThing	nonadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of nonadec-1-ene.	got7fsn_ti	nonadec-1-ene anabolism|nonadec-1-ene synthesis|nonadec-1-ene formation|nonadec-1-ene biosynthesis						tt	2012-06-13T01:52:37Z						biological_process											owl:Class	
GO:0015717	biolink:NamedThing	triose phosphate transport	The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	aldotriose phosphate transport													biological_process											owl:Class	
CL:1000692	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061906	biolink:NamedThing	autophagosome localization	Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell.	got7fsn_ti							dph	2017-06-28T17:27:57Z						biological_process											owl:Class	
CHEBI:36241	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902644	biolink:NamedThing	tertiary alcohol metabolic process	The chemical reactions and pathways involving tertiary alcohol.	got7fsn_ti	tertiary alcohol metabolism						tt	2014-01-21T17:53:53Z						biological_process											owl:Class	
GO:0045351	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006724	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:53388	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35368	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006288	biolink:NamedThing	base-excision repair, DNA ligation	The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair.	got7fsn_ti														biological_process											owl:Class	
GO:0007255	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019091	biolink:NamedThing	mitochondrial lrRNA export from mitochondrion	The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.	got7fsn_ti	export of mitochondrial lrRNA|mitochondrial lrRNA, mitochondrial export|mitochondrial lrRNA export from mitochondria|mitochondrial lrRNA export|mitochondrial lrRNA transport from mitochondrion|mitochondrial lrRNA export out of mitochondrion													biological_process											owl:Class	
GO:0030452	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:1269	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18305	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009072	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005553	biolink:NamedThing	obsolete ubiquitin-ribosomal protein fusion protein	OBSOLETE. A protein encoded by some ubiquitin genes which consists of a single copy of ubiquitin fused to a ribosomal protein.	got7fsn_ti	ubiquitin-ribosomal protein fusion protein				This term was made obsolete because it describes a gene product.					True				molecular_function											owl:Class	
GO:0072745	biolink:NamedThing	cellular response to antimycin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.	got7fsn_ti							mah	2012-08-31T12:31:08Z						biological_process											owl:Class	
CHEBI:61375	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098950	biolink:NamedThing	intrinsic component of postsynaptic early endosome membrane	The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	got7fsn_ti	intrinsic to postsynaptic early endosome membrane													cellular_component											owl:Class	
CHEBI:24353	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005330	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001208	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003081	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003821	biolink:NamedThing	obsolete class II major histocompatibility complex antigen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	class II major histocompatibility complex antigen				This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.	GO:0042613				True				molecular_function											owl:Class	
GO:0006050	biolink:NamedThing	mannosamine metabolic process	The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.	got7fsn_ti	mannosamine metabolism													biological_process											owl:Class	
GO:0075318	biolink:NamedThing	regulation of ascus development	Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.	got7fsn_ti														biological_process											owl:Class	
PR:000001656	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901273	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid.	got7fsn_ti	2-dehydro-3-deoxy-D-gluconic acid degradation|2-dehydro-3-deoxy-D-gluconic acid catabolism|2-dehydro-3-deoxy-D-gluconic acid breakdown						yaf	2012-08-17T14:46:37Z						biological_process											owl:Class	
GO:0062233	biolink:NamedThing	F2-isoprostane catabolic process	The chemical reactions and pathways resulting in the breakdown of F2-isoprostane.	got7fsn_ti							dph	2020-03-23T15:24:38Z						biological_process											owl:Class	
CHEBI:17393	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071211	biolink:NamedThing	protein targeting to vacuole involved in autophagy	The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.	got7fsn_ti	protein targeting to autophagosome						mah	2009-11-25T02:25:27Z						biological_process											owl:Class	
GO:0008891	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:67148	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000110	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016169	biolink:NamedThing	bacteriochlorophyll c binding	Binding to bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:64410	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005083	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000009001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901365	biolink:NamedThing	funalenone catabolic process	The chemical reactions and pathways resulting in the breakdown of funalenone.	got7fsn_ti	funalenone catabolism|funalenone degradation|funalenone breakdown						di	2012-09-17T18:25:29Z						biological_process											owl:Class	
GO:0051874	biolink:NamedThing	sphinganine-1-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.	got7fsn_ti	dihydrosphingosine-1-phosphate catabolism|dihydrosphingosine-1-phosphate catabolic process													biological_process											owl:Class	
GO:0046781	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OIO:id	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
CHEBI:70726	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002342	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902741	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061915	biolink:NamedThing	actin fusion focus localization	Any process in which an actin fusion focus are transported to, or maintained in, a specific location. The actin fusion focus is an aster-like, F-actin-containing structure at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion.	got7fsn_ti	actin fusion focus localisation						dph	2017-07-10T18:11:47Z						biological_process											owl:Class	
GO:0022814	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075047	biolink:NamedThing	negative regulation of formation by symbiont of haustorium for nutrient acquisition from host	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.									biological_process											owl:Class	
CHEBI:15948	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58190	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004196	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003888	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904681	biolink:NamedThing	response to 3-methylcholanthrene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.	got7fsn_ti							mr	2015-09-22T19:50:03Z						biological_process											owl:Class	
GO:0052123	biolink:NamedThing	obsolete negative chemotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	negative chemotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0051789	biolink:NamedThing	obsolete response to protein	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus.	got7fsn_ti	response to protein stimulus|response to protein				This term was made obsolete because more specific terms exist.	GO:0051788|GO:0034097|GO:0006986|GO:0070848|GO:0009725				True				biological_process											owl:Class	
GO:0052224	biolink:NamedThing	obsolete energy taxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism within a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	got7fsn_ti	energy taxis within other organism during symbiotic interaction|energy taxis in other organism during symbiotic interaction				This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
PR:000006928	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900729	biolink:NamedThing	regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.	got7fsn_ti	regulation of inhibition of adenylate cyclase activity by opioid receptor|regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway|regulation of opioid receptor-mediated adenylate cyclase inhibition|regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway						bf	2012-05-25T03:20:49Z						biological_process											owl:Class	
GO:0030361	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005062	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64599	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000797	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:24828	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060554	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0061210	biolink:NamedThing	cell-cell signaling involved in mesonephros development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.	got7fsn_ti	cell-cell signalling involved in mesonephros development						dph	2010-08-17T03:24:08Z						biological_process											owl:Class	
CHEBI:24265	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59414	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025197	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006829	biolink:NamedThing	zinc ion transport	The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	zinc transport|zinc II ion transport													biological_process											owl:Class	
GO:0015255	biolink:NamedThing	propanediol channel activity	Enables the facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	got7fsn_ti														molecular_function											owl:Class	
GO:0010697	biolink:NamedThing	negative regulation of mitotic spindle pole body separation	Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.	got7fsn_ti	negative regulation of SPB separation													biological_process											owl:Class	
CL:0000794	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034913	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006743	biolink:NamedThing	ubiquinone metabolic process	The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme.	got7fsn_ti	coenzyme Q metabolic process|coenzyme Q metabolism|ubiquinone metabolism													biological_process											owl:Class	
GO:0046368	biolink:NamedThing	GDP-L-fucose metabolic process	The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.	got7fsn_ti	GDP-L-fucose metabolism													biological_process											owl:Class	
GO:0075083	biolink:NamedThing	obsolete negative regulation by host of symbiont transmembrane receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
CHEBI:6497	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57454	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070203	biolink:NamedThing	regulation of establishment of protein localization to telomere	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome.	got7fsn_ti	regulation of establishment of protein localisation to telomere													biological_process											owl:Class	
CHEBI:16634	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001120	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006871	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043088	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0034307	biolink:NamedThing	regulation of ascospore formation	Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.	got7fsn_ti	MAPKKK cascade during sporulation													biological_process											owl:Class	
GO:1901334	biolink:NamedThing	lactone metabolic process	The chemical reactions and pathways involving lactone.	got7fsn_ti	lactone metabolism						bf	2012-09-03T10:26:00Z						biological_process											owl:Class	
CHEBI:356416	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:47781	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904547	biolink:NamedThing	regulation of cellular response to glucose starvation	Any process that modulates the frequency, rate or extent of cellular response to glucose starvation.	got7fsn_ti							al	2015-08-12T09:57:52Z						biological_process											owl:Class	
GO:0046369	biolink:NamedThing	galactose biosynthetic process	The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose.	got7fsn_ti	galactose synthesis|galactose formation|galactose anabolism|galactose biosynthesis													biological_process											owl:Class	
CL:0001658	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001468	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17757	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001105	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052065	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1903004	biolink:NamedThing	regulation of protein K63-linked deubiquitination	Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination.	got7fsn_ti							bf	2014-05-12T15:40:43Z						biological_process											owl:Class	
UBERON:0000970	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001117	biolink:NamedThing	tetrahydromethanopterin metabolic process	The chemical reactions and pathways involving a tetrahydromethanopterin.	got7fsn_ti	tetrahydromethanopterin metabolism						jl	2011-10-11T12:13:15Z						biological_process											owl:Class	
CHEBI:62937	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006709	biolink:NamedThing	progesterone catabolic process	The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.	got7fsn_ti	progesterone degradation|progesterone catabolism|progesterone breakdown													biological_process											owl:Class	
GO:0033294	biolink:NamedThing	ectoine binding	Binding to ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid.	got7fsn_ti														molecular_function											owl:Class	
GO:0098766	biolink:NamedThing	obsolete meiosis I M phase	OBSOLETE. M phase during meiosis I.	got7fsn_ti					Obsoleted because added in error.	GO:0098762				True				biological_process											owl:Class	
GO:0098726	biolink:NamedThing	symmetric division of skeletal muscle satellite stem cell	The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells.  This process is involved in amplification of the pool of these cells.	got7fsn_ti														biological_process											owl:Class	
GO:0005341	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:1000022	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50699	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901210	biolink:NamedThing	regulation of cardiac chamber formation	Any process that modulates the frequency, rate or extent of cardiac chamber formation.	got7fsn_ti	regulation of heart chamber formation						rl	2012-07-31T07:18:35Z						biological_process											owl:Class	
CHEBI:30584	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002350	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18320	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23248	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018383	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001185	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007988	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:41879	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002514	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902111	biolink:NamedThing	response to diethyl maleate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.	got7fsn_ti							mah	2013-05-08T16:00:35Z						biological_process											owl:Class	
GO:1902256	biolink:NamedThing	regulation of apoptotic process involved in outflow tract morphogenesis	Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.	got7fsn_ti	regulation of apoptosis involved in outflow tract morphogenesis						dph	2013-06-24T19:12:24Z						biological_process											owl:Class	
UBERON:0002079	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002110	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0100022	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005075	biolink:NamedThing	obsolete pathway-specific SMAD protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	pathway-specific SMAD protein				This term was made obsolete because it represents a family of gene products.					True				molecular_function											owl:Class	
CHEBI:6923	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070433	biolink:NamedThing	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.	got7fsn_ti	negative regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway|negative regulation of NOD2 signaling pathway													biological_process											owl:Class	
UBERON:0004206	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030071	biolink:NamedThing	regulation of mitotic metaphase/anaphase transition	Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.	got7fsn_ti														biological_process											owl:Class	
UBERON:0002164	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:10221	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070345	biolink:NamedThing	negative regulation of fat cell proliferation	Any process that stops or decreases the rate or extent of fat cell proliferation.	got7fsn_ti	negative regulation of adipose cell proliferation|down-regulation of fat cell proliferation|negative regulation of adipocyte proliferation|inhibition of fat cell proliferation|down regulation of fat cell proliferation|downregulation of fat cell proliferation													biological_process											owl:Class	
GO:0006492	biolink:NamedThing			got7fsn_ti										True															owl:Class	
dc:description	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
CHEBI:62932	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17814	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075237	biolink:NamedThing	obsolete obsolete negative regulation of zoospore movement on or near host	OBSOLETE. OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
CHEBI:133011	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002185	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61444	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015321	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051489	biolink:NamedThing	regulation of filopodium assembly	Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.	got7fsn_ti	regulation of filopodium formation|regulation of filopodia biosynthesis|regulation of filopodia formation													biological_process											owl:Class	
CHEBI:57753	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903551	biolink:NamedThing	regulation of extracellular exosome assembly	Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.	got7fsn_ti	regulation of extracellular vesicular exosome assembly						pga	2014-10-20T15:37:25Z						biological_process											owl:Class	
GO:0030475	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004680	biolink:NamedThing	obsolete casein kinase activity	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	casein kinase activity			GO:0004674	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:32544	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015727	biolink:NamedThing	lactate transport	The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.	got7fsn_ti														biological_process											owl:Class	
GO:1900908	biolink:NamedThing	regulation of olefin metabolic process	Any process that modulates the frequency, rate or extent of olefin metabolic process.	got7fsn_ti	regulation of olefin metabolism						tt	2012-06-13T04:18:29Z						biological_process											owl:Class	
CHEBI:16220	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099089	biolink:NamedThing	establishment of endoplasmic reticulum localization to postsynapse	The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine.	got7fsn_ti	establishment of ER localization to postsynapse													biological_process											owl:Class	
GO:0045113	biolink:NamedThing	regulation of integrin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.	got7fsn_ti	regulation of integrin synthesis|regulation of integrin formation|regulation of integrin anabolism|regulation of integrin biosynthesis													biological_process											owl:Class	
SO:0000593	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000012421	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008598	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052169	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response	OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	pathogen-associated molecular pattern dependent modulation by symbiont of host innate immunity				This term was obsoleted because it has been misused.	GO:0052034|GO:0002221|GO:0002752				True				biological_process											owl:Class	
GO:2000458	biolink:NamedThing	regulation of astrocyte chemotaxis	Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.	got7fsn_ti							bf	2011-03-04T10:53:50Z						biological_process											owl:Class	
GO:0022026	biolink:NamedThing	epidermal growth factor signaling pathway involved in forebrain neuron fate commitment	The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	got7fsn_ti	epidermal growth factor signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
CHEBI:28600	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000018	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28831	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046312	biolink:NamedThing	phosphoarginine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine.	got7fsn_ti	phosphoarginine synthesis|phosphoarginine anabolism|phosphoarginine biosynthesis|phosphoarginine formation													biological_process											owl:Class	
CHEBI:60270	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64542	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900640	biolink:NamedThing	regulation of austinol biosynthetic process	Any process that modulates the frequency, rate or extent of austinol biosynthetic process.	got7fsn_ti	regulation of austinol synthesis|regulation of austinol biosynthesis|regulation of austinol anabolism|regulation of austinol formation						di	2012-05-22T03:57:33Z						biological_process											owl:Class	
CL:0000740	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000247	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26392	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:2679	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27066	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001287	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900875	biolink:NamedThing	heptadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of heptadec-1-ene.	got7fsn_ti	heptadec-1-ene biosynthesis|heptadec-1-ene synthesis|heptadec-1-ene anabolism|heptadec-1-ene formation						tt	2012-06-13T01:50:11Z						biological_process											owl:Class	
GO:1901535	biolink:NamedThing	regulation of DNA demethylation	Any process that modulates the frequency, rate or extent of DNA demethylation.	got7fsn_ti							jl	2012-10-24T13:52:50Z						biological_process											owl:Class	
GO:0044005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048696	biolink:NamedThing	regulation of collateral sprouting in absence of injury	Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.	got7fsn_ti														biological_process											owl:Class	
GO:0031374	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0004149	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004884	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901864	biolink:NamedThing	capsorubin metabolic process	The chemical reactions and pathways involving capsorubin.	got7fsn_ti	capsorubin metabolism						yaf	2013-02-04T10:50:13Z						biological_process											owl:Class	
GO:0046999	biolink:NamedThing	regulation of conjugation	Any process that modulates the rate or frequency of conjugation, the union or introduction of genetic information from compatible mating types that results in a genetically different individual.	got7fsn_ti														biological_process											owl:Class	
PO:0025023	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0110151	biolink:NamedThing	positive regulation of biomineralization	Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.	got7fsn_ti	positive regulation of mineralization|positive regulation of mineralisation|positive regulation of biomineralisation|positive regulation of biomineral formation						kmv	2019-06-10T18:18:01Z						biological_process											owl:Class	
GO:0021733	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010982	biolink:NamedThing	regulation of high-density lipoprotein particle clearance	Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	got7fsn_ti							tb	2009-06-01T12:01:30Z						biological_process											owl:Class	
CHEBI:50674	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17694	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120190	biolink:NamedThing	negative regulation of bile acid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.	got7fsn_ti							krc	2018-07-16T22:38:34Z						biological_process											owl:Class	
UBERON:0001045	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0062247	biolink:NamedThing	chloroplast vesicle	A intracellular vesicle that is part of a chloroplast.	got7fsn_ti							dph	2020-05-01T12:10:16Z						cellular_component											owl:Class	
GO:0001523	biolink:NamedThing	retinoid metabolic process	The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.	got7fsn_ti	retinoid metabolism													biological_process											owl:Class	
CHEBI:60835	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0039582	biolink:NamedThing	obsolete suppression by virus of host PKR activity by positive regulation of PKR nuclear localization	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the localization of PKR in the nucleus. For example, human cytomegalovirus (HMCV) gene products directly interact with PKR and inhibit its activation by sequestering it in the nucleus, away from both its activator (cytoplasmic dsRNA) and its substrate, (eIF2alpha).	got7fsn_ti	suppression by virus of host PKR activity by nuclear sequestration of PKR|suppression by virus of host PKR activity by sequestering of PKR in nucleus|suppression by virus of host PKR activity by positive regulation of PKR localization to nucleus				The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True				biological_process											owl:Class	
CHEBI:22599	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033160	biolink:NamedThing	obsolete positive regulation of protein import into nucleus, translocation	OBSOLETE. Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.	got7fsn_ti	positive regulation of protein import into cell nucleus, translocation				This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True				biological_process											owl:Class	
GO:0060968	biolink:NamedThing	regulation of gene silencing	Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.	got7fsn_ti							dph	2009-10-05T03:23:56Z						biological_process											owl:Class	
GO:0071642	biolink:NamedThing	positive regulation of macrophage inflammatory protein 1 alpha production	Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.	got7fsn_ti	positive regulation of macrophage inflammatory protein production|positive regulation of MIP-1a production|positive regulation of CCL3 production|positive regulation of chemokine (C-C motif) ligand 3 production						mah	2010-02-12T10:39:51Z						biological_process											owl:Class	
CL:0000566	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:2000001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001579	biolink:NamedThing	medium-chain fatty acid transport	The directed movement of medium-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.	got7fsn_ti														biological_process											owl:Class	
GO:0140206	biolink:NamedThing	dipeptide import across plasma membrane	The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-02-22T15:49:19Z						biological_process											owl:Class	
GO:1904611	biolink:NamedThing	cellular response to 3,3',4,4',5-pentachlorobiphenyl	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.	got7fsn_ti	cellular response to PCB 126						sl	2015-08-27T18:52:55Z						biological_process											owl:Class	
GO:0032875	biolink:NamedThing	regulation of DNA endoreduplication	Any process that modulates the frequency, rate or extent of DNA endoreduplication.	got7fsn_ti	regulation of DNA re-duplication|regulation of DNA endoreplication													biological_process											owl:Class	
GO:2000161	biolink:NamedThing	regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.	got7fsn_ti							dph	2010-10-05T01:05:21Z						biological_process											owl:Class	
GO:0002689	biolink:NamedThing	negative regulation of leukocyte chemotaxis	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.	got7fsn_ti	inhibition of leukocyte chemotaxis|negative regulation of immune cell chemotaxis|negative regulation of leucocyte chemotaxis|downregulation of leukocyte chemotaxis|down regulation of leukocyte chemotaxis|down-regulation of leukocyte chemotaxis													biological_process											owl:Class	
CHEBI:57925	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015289	biolink:NamedThing	obsolete pore-forming toxin activity	OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.	got7fsn_ti	pore-forming toxin activity				This term was made obsolete because it represents a class of gene products.	GO:0005198|GO:0090729|GO:0046931|GO:0046930				True				molecular_function											owl:Class	
CHEBI:67247	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048305	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010685	biolink:NamedThing	tetracyclic triterpenoid metabolic process	The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.	got7fsn_ti	tetracyclic triterpenoid metabolism													biological_process											owl:Class	
GO:0090023	biolink:NamedThing	positive regulation of neutrophil chemotaxis	Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	got7fsn_ti							tb	2009-08-03T10:12:23Z						biological_process											owl:Class	
CL:1000742	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902826	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:60471	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071584	biolink:NamedThing	negative regulation of zinc ion transmembrane import	Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.	got7fsn_ti							mah	2010-01-28T03:17:21Z						biological_process											owl:Class	
GO:2001027	biolink:NamedThing	negative regulation of endothelial cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.	got7fsn_ti							rl	2011-08-22T01:07:31Z						biological_process											owl:Class	
GO:0046496	biolink:NamedThing	nicotinamide nucleotide metabolic process	The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.	got7fsn_ti	nicotinamide nucleotide metabolism													biological_process											owl:Class	
GO:0052930	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075144	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000230	biolink:NamedThing	negative regulation of pancreatic stellate cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation.	got7fsn_ti							mah	2010-11-09T03:45:21Z						biological_process											owl:Class	
GO:2001164	biolink:NamedThing	negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.	got7fsn_ti							se	2011-10-25T10:31:03Z						biological_process											owl:Class	
GO:1904391	biolink:NamedThing	response to ciliary neurotrophic factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.	got7fsn_ti							sl	2015-06-23T19:13:04Z						biological_process											owl:Class	
GO:0062067	biolink:NamedThing	chloroplast photosystem I binding	Binding to a chloroplast photosystem I.	got7fsn_ti							dph	2018-08-31T14:07:46Z						molecular_function											owl:Class	
GO:0043555	biolink:NamedThing	regulation of translation in response to stress	Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	got7fsn_ti	translational stress response													biological_process											owl:Class	
CHEBI:27150	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025545	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000851	biolink:NamedThing	positive regulation of glucocorticoid secretion	Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion.	got7fsn_ti							bf	2011-07-26T08:44:51Z						biological_process											owl:Class	
CHEBI:4470	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006173	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033465	biolink:NamedThing	cis-zeatin biosynthetic process	The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	got7fsn_ti	cis-zeatin biosynthesis|cis-zeatin synthesis|cis-zeatin anabolism|cis-zeatin formation											MetaCyc:PWY-2781		biological_process											owl:Class	
PO:0020003	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001564	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097334	biolink:NamedThing	response to perphenazine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.	got7fsn_ti							pr	2012-06-12T11:01:14Z						biological_process											owl:Class	
GO:0097032	biolink:NamedThing	obsolete mitochondrial respiratory chain complex II biogenesis	OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex II, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/15173			The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		pr	2011-04-05T02:57:33Z		True				biological_process											owl:Class	
PR:000001902	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060634	biolink:NamedThing	regulation of 4,6-pyruvylated galactose residue biosynthetic process	Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.	got7fsn_ti							dph	2009-05-18T03:15:39Z						biological_process											owl:Class	
GO:0031273	biolink:NamedThing	negative regulation of pseudopodium assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia.	got7fsn_ti	downregulation of pseudopodium formation|negative regulation of pseudopodium formation|down-regulation of pseudopodium formation|down regulation of pseudopodium formation|inhibition of pseudopodium formation													biological_process											owl:Class	
GO:0043962	biolink:NamedThing	obsolete negative regulation by host of symbiont adenylate cyclase-mediated signal transduction	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True				biological_process											owl:Class	
CHEBI:60977	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0100062	biolink:NamedThing	obsolete positive regulation of SREBP signaling pathway by transcription factor catabolic process	OBSOLETE. Any transcription factor catabolic process process that positively_regulates SREBP signaling pathway.	got7fsn_ti					The reason for obsoletion is that this term should be represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True				biological_process											owl:Class	
CHEBI:27569	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28145	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010769	biolink:NamedThing	regulation of cell morphogenesis involved in differentiation	Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	got7fsn_ti														biological_process											owl:Class	
CHEBI:17437	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:49870	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001132	biolink:NamedThing	obsolete RNA polymerase II transcription factor activity, TBP-class protein binding	OBSOLETE. Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	got7fsn_ti	TATA-binding protein binding RNA polymerase II transcription factor activity|TBP-class protein binding RNA polymerase II transcription factor activity|TRF protein binding RNA polymerase II transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053			The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.		krc	2011-01-20T04:15:44Z		True				molecular_function											owl:Class	
UBERON:0003097	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001719	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000410	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052778	biolink:NamedThing	diacetylchitobiose metabolic process	The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose.	got7fsn_ti	diacetylchitobiose metabolism													biological_process											owl:Class	
GO:0070361	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:15443	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016975	biolink:NamedThing	obsolete alpha-2 macroglobulin	OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates.	got7fsn_ti	alpha-2 macroglobulin			GO:0004866	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:6178	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000223	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35381	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24318	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000025848	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16651	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006717	biolink:NamedThing	obsolete juvenile hormone binding	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	juvenile hormone binding				This term was made obsolete because it represents a molecular function and not a biological process.	GO:0005500				True				biological_process											owl:Class	
CHEBI:3378	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28874	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043538	biolink:NamedThing	regulation of actin phosphorylation	Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule.	got7fsn_ti														biological_process											owl:Class	
UBERON:0002956	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904264	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001366	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004205	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000017283	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46761	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005141	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007893	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990106	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015609	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57585	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46912	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000004140	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046441	biolink:NamedThing	D-lysine metabolic process	The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.	got7fsn_ti	D-lysine metabolism													biological_process											owl:Class	
GO:1905213	biolink:NamedThing	negative regulation of mitotic chromosome condensation	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation.	got7fsn_ti							vw	2016-06-03T08:41:08Z						biological_process											owl:Class	
CHEBI:17327	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046096	biolink:NamedThing	deoxyuridine metabolic process	The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.	got7fsn_ti	deoxyuridine metabolism													biological_process											owl:Class	
GO:0045810	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905896	biolink:NamedThing	positive regulation of cellular response to tunicamycin	Any process that activates or increases the frequency, rate or extent of cellular response to tunicamycin.	got7fsn_ti	upregulation of cellular response to tunicamycin|activation of cellular response to tunicamycin|up regulation of cellular response to tunicamycin|up-regulation of cellular response to tunicamycin						bc	2017-02-01T11:36:51Z						biological_process											owl:Class	
UBERON:0000966	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140213	biolink:NamedThing	negative regulation of long-chain fatty acid import into cell	Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell.	got7fsn_ti							pg	2018-04-10T15:13:28Z						biological_process											owl:Class	
GO:0106001	biolink:NamedThing	intestinal hexose absorption	Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.	got7fsn_ti														biological_process											owl:Class	
GO:0071388	biolink:NamedThing	cellular response to cortisone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.	got7fsn_ti							mah	2009-12-11T03:57:59Z						biological_process											owl:Class	
GO:1905905	biolink:NamedThing	pharyngeal gland morphogenesis	The developmental process by which a pharyngeal gland is generated and organized.	got7fsn_ti	pharynx gland morphogenesis|glandulae pharyngeae morphogenesis						rz	2017-02-03T14:39:10Z						biological_process											owl:Class	
GO:0110061	biolink:NamedThing	regulation of angiotensin-activated signaling pathway	Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway.	got7fsn_ti							kmv	2017-10-26T17:37:37Z						biological_process											owl:Class	
CHEBI:25640	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032113	biolink:NamedThing	regulation of carbohydrate phosphatase activity	Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate.	got7fsn_ti														biological_process											owl:Class	
GO:0000057	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002534	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045646	biolink:NamedThing	regulation of erythrocyte differentiation	Any process that modulates the frequency, rate or extent of erythrocyte differentiation.	got7fsn_ti	regulation of RBC differentiation|regulation of red blood cell differentiation													biological_process											owl:Class	
CHEBI:33731	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052517	biolink:NamedThing	obsolete positive regulation by organism of symbiont non-apoptotic programmed cell death	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation by organism of symbiont non-apoptotic programmed cell death				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0051828	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140203	biolink:NamedThing	spermidine import across plasma membrane	The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							pg	2018-02-21T19:10:07Z						biological_process											owl:Class	
GO:0100067	biolink:NamedThing	positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway	Any canonical Wnt signaling pathway process that positively_regulates spinal cord association neuron differentiation.	got7fsn_ti							cjm	2015-04-02T04:13:19Z						biological_process											owl:Class	
GO:0030765	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:5391	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37166	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:10983	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000033	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002325	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032445	biolink:NamedThing	fructose import	The directed movement of the hexose monosaccharide fructose into a cell or organelle.	got7fsn_ti	fructose uptake													biological_process											owl:Class	
PR:000016964	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:91020	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_33281	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000656	biolink:NamedThing	regulation of apolipoprotein binding	Any process that modulates the frequency, rate or extent of apolipoprotein binding.	got7fsn_ti							vk	2011-05-02T05:33:41Z						biological_process											owl:Class	
GO:2001146	biolink:NamedThing	positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.	got7fsn_ti							yaf	2011-10-19T10:41:30Z						biological_process											owl:Class	
UBERON:0004179	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019519	biolink:NamedThing	pentitol metabolic process	The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule.	got7fsn_ti	pentitol metabolism													biological_process											owl:Class	
GO:0008221	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:26398	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075142	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032500	biolink:NamedThing	muramyl dipeptide binding	Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.	got7fsn_ti														molecular_function											owl:Class	
UBERON:0004194	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046328	biolink:NamedThing	regulation of JNK cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.	got7fsn_ti	regulation of SAPK cascade													biological_process											owl:Class	
PO:0009001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903564	biolink:NamedThing	regulation of protein localization to cilium	Any process that modulates the frequency, rate or extent of protein localization to cilium.	got7fsn_ti							krc	2014-10-24T20:58:11Z						biological_process											owl:Class	
GO:2000299	biolink:NamedThing	negative regulation of Rho-dependent protein serine/threonine kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.	got7fsn_ti	negative regulation of Rho-associated protein kinase activity|negative regulation of ROCK kinase activity						mah	2010-12-23T11:44:57Z						biological_process											owl:Class	
GO:0070273	biolink:NamedThing	phosphatidylinositol-4-phosphate binding	Binding to phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.	got7fsn_ti														molecular_function											owl:Class	
GO:0099104	biolink:NamedThing	potassium channel activator activity	Binds to and increases the activity of a potassium channel, resulting in its opening.	got7fsn_ti														molecular_function											owl:Class	
GO:0031067	biolink:NamedThing	negative regulation of histone deacetylation at centromere	Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups to histones in centromeric DNA.	got7fsn_ti	down-regulation of histone deacetylation at centromere|inhibition of histone deacetylation at centromere|downregulation of histone deacetylation at centromere|down regulation of histone deacetylation at centromere													biological_process											owl:Class	
GO:0045316	biolink:NamedThing	negative regulation of compound eye photoreceptor development	Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development.	got7fsn_ti	down-regulation of eye photoreceptor development|inhibition of eye photoreceptor development|downregulation of eye photoreceptor development|down regulation of eye photoreceptor development|negative regulation of eye photoreceptor development													biological_process											owl:Class	
GO:0002650	biolink:NamedThing	negative regulation of tolerance induction to self antigen	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen.	got7fsn_ti	down-regulation of tolerance induction to self antigen|down regulation of tolerance induction to self antigen|downregulation of tolerance induction to self antigen|inhibition of tolerance induction to self antigen													biological_process											owl:Class	
GO:0033003	biolink:NamedThing	regulation of mast cell activation	Any process that modulates the frequency, rate, or extent of mast cell activation.	got7fsn_ti														biological_process											owl:Class	
CHEBI:82705	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000172	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000003112	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57792	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008618	biolink:NamedThing	7-methylguanosine metabolic process	The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.	got7fsn_ti	7-methylguanosine metabolism													biological_process											owl:Class	
GO:0001599	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:1001474	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045118	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036103	biolink:NamedThing	Kdo2-lipid A metabolic process	The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component.	got7fsn_ti	Kdo2-lipid A metabolism						bf	2012-01-27T01:49:16Z						biological_process											owl:Class	
GO:0086078	biolink:NamedThing	gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	got7fsn_ti							dph	2011-11-22T10:34:13Z						molecular_function											owl:Class	
GO:1904272	biolink:NamedThing	L-tryptophan import across plasma membrane	The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti							kmv	2015-05-29T13:39:27Z						biological_process											owl:Class	
GO:0015972	biolink:NamedThing	guanosine pentaphosphate metabolic process	The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.	got7fsn_ti	guanosine pentaphosphate (5'-pppGpp-3') metabolism|guanosine pentaphosphate metabolism|guanosine pentaphosphate (5'-pppGpp-3') metabolic process													biological_process											owl:Class	
GO:0062034	biolink:NamedThing	L-pipecolic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine.	got7fsn_ti	L-pipecolate biosynthetic process						dph	2018-04-24T12:19:36Z						biological_process											owl:Class	
GO:0019811	biolink:NamedThing	cocaine binding	Binding to cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:40910	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0062142	biolink:NamedThing	L-beta-ethynylserine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/17763					dph	2019-09-02T16:39:59Z						biological_process											owl:Class	
CHEBI:60187	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044792	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:46819	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17387	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57492	biolink:NamedThing			got7fsn_ti																									owl:Class	
NCBITaxon:33630	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031006	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002324	biolink:NamedThing	natural killer cell proliferation involved in immune response	The expansion of a natural killer cell population by cell division as part of an immune response.	got7fsn_ti	natural killer cell proliferation during immune response|NK cell proliferation during immune response													biological_process											owl:Class	
CHEBI:17347	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032565	biolink:NamedThing	dGMP binding	Binding to dGMP, deoxyguanosine monophosphate.	got7fsn_ti														molecular_function											owl:Class	
UBERON:0000042	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051174	biolink:NamedThing	regulation of phosphorus metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.	got7fsn_ti	regulation of phosphorus metabolism													biological_process											owl:Class	
CHEBI:60151	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002153	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58439	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001820	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005536	biolink:NamedThing	glucose binding	Binding to D- or L-enantiomers of glucose.	got7fsn_ti														molecular_function											owl:Class	
GO:0075273	biolink:NamedThing	positive regulation of zygosporangium development	Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.	got7fsn_ti														biological_process											owl:Class	
CHEBI:73477	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:65318	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001168	biolink:NamedThing	positive regulation of histone H2B ubiquitination	Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination.	got7fsn_ti							se	2011-10-25T10:50:01Z						biological_process											owl:Class	
GO:1905721	biolink:NamedThing	mitotic spindle astral microtubule end	Any microtubule end that is part of a mitotic spindle astral microtubule.	got7fsn_ti	mitotic spindle astral microtubule tip						vw	2016-11-25T12:26:18Z						cellular_component											owl:Class	
GO:0042226	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003124	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52973	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001055	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process	Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.	got7fsn_ti	positive regulation of mesenchymal cell apoptosis						yaf	2011-09-08T02:50:09Z						biological_process											owl:Class	
UBERON:0001897	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007555	biolink:NamedThing	regulation of ecdysteroid secretion	Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell.	got7fsn_ti														biological_process											owl:Class	
GO:0039655	biolink:NamedThing	obsolete transport of virus in host, cell to cell via plasmodesmata	OBSOLETE. The transport of a virus between adjacent cells in a multicellular organism using plasmodesmata. Plasmodesma is a fine cytoplasmic channel found in all higher plants, which connects the cytoplasm of one cell to that of an adjacent cell.	got7fsn_ti	viral movement protein|spread of virus in host, cell to cell via plasmodesmata						bf	2013-06-20T14:47:50Z		True		VZ:1018		biological_process											owl:Class	
PO:0009035	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0017173	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000008725	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035257	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:34779	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002410	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002880	biolink:NamedThing	regulation of chronic inflammatory response to non-antigenic stimulus	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0051557	biolink:NamedThing	leucoanthocyanidin biosynthetic process	The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.	got7fsn_ti														biological_process											owl:Class	
CL:0000586	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000043	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33856	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032556	biolink:NamedThing	pyrimidine deoxyribonucleotide binding	Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	got7fsn_ti														molecular_function											owl:Class	
GO:0106025	biolink:NamedThing	positive regulation of pupariation	Any process that activates or increases the frequency, rate or extent of onset of pupariation.	got7fsn_ti							hjd	2017-05-24T19:37:50Z						biological_process											owl:Class	
GO:0016151	biolink:NamedThing	nickel cation binding	Binding to a nickel (Ni) cation.	got7fsn_ti	Ni binding|nickel binding													molecular_function											owl:Class	
CL:0005019	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57746	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002146	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071672	biolink:NamedThing	negative regulation of smooth muscle cell chemotaxis	Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.	got7fsn_ti	downregulation of smooth muscle cell chemotaxis|down-regulation of smooth muscle cell chemotaxis|inhibition of smooth muscle cell chemotaxis|down regulation of smooth muscle cell chemotaxis						mah	2010-02-16T01:44:28Z						biological_process											owl:Class	
GO:1902746	biolink:NamedThing	regulation of lens fiber cell differentiation	Any process that modulates the frequency, rate or extent of lens fiber cell differentiation.	got7fsn_ti	regulation of lens fibre cell differentiation						mr	2014-03-03T23:18:50Z						biological_process											owl:Class	
GO:0034443	biolink:NamedThing	negative regulation of lipoprotein oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation.	got7fsn_ti	inhibition of lipoprotein oxidation													biological_process											owl:Class	
GO:2000562	biolink:NamedThing	negative regulation of CD4-positive, alpha-beta T cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.	got7fsn_ti							ebc	2011-04-03T09:01:11Z						biological_process											owl:Class	
CHEBI:27641	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000561	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052931	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006660	biolink:NamedThing	phosphatidylserine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.	got7fsn_ti	phosphatidylserine catabolism|phosphatidylserine breakdown|phosphatidylserine degradation													biological_process											owl:Class	
UBERON:0007842	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0062226	biolink:NamedThing	regulation of adult somatic muscle development	Any process that modulates the rate, frequency or extent of adult somatic muscle development.	got7fsn_ti							dph	2020-03-16T13:24:07Z						biological_process											owl:Class	
GO:0051928	biolink:NamedThing	positive regulation of calcium ion transport	Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti	up regulation of calcium ion transport|up-regulation of calcium ion transport|positive regulation of calcium transport|stimulation of calcium ion transport|upregulation of calcium ion transport|activation of calcium ion transport													biological_process											owl:Class	
UBERON:0005140	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030939	biolink:NamedThing	obsolete response to long-day photoperiod	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the light phase being longer than the dark.	got7fsn_ti	response to long-day photoperiod				This term was made obsolete because it was wrongly defined.	GO:0048571				True				biological_process											owl:Class	
UBERON:0001781	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032377	biolink:NamedThing	regulation of intracellular lipid transport	Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.	got7fsn_ti														biological_process											owl:Class	
CL:2000022	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072347	biolink:NamedThing	response to anesthetic	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.	got7fsn_ti	response to anaesthetic						mah	2010-11-10T01:26:18Z						biological_process											owl:Class	
SO:0001799	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097369	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000068	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29749	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990847	biolink:NamedThing	obsolete peptide pheromone transmembrane export involved in positive regulation of conjugation with cellular fusion	OBSOLETE. The directed movement of a peptide pheromone across a membrane and out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20310			This term was obsoleted because it represents a BP in a BP and should be captured with a GO-CAM model		al	2015-09-08T15:23:26Z		True				biological_process											owl:Class	
CHEBI:53030	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008151	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046350	biolink:NamedThing	galactosaminoglycan metabolic process	The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose.	got7fsn_ti	galactosaminoglycan metabolism													biological_process											owl:Class	
CL:0000138	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020099	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005099	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28619	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0080033	biolink:NamedThing	response to nitrite	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0016326	biolink:NamedThing	obsolete kinesin motor activity	OBSOLETE. The hydrolysis of ATP (and GTP) that drives the microtubular motor along microtubules.	got7fsn_ti	kinesin motor activity			GO:0003777	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
CHEBI:5613	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016089	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PO:0009031	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001062	biolink:NamedThing	xylan binding	Binding to xylan.	got7fsn_ti							jl	2011-09-14T10:10:04Z						molecular_function											owl:Class	
GO:0019742	biolink:NamedThing	pentacyclic triterpenoid metabolic process	The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.	got7fsn_ti	pentacyclic triterpenoid metabolism													biological_process											owl:Class	
GO:0006159	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:37239	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071777	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:GOCHE_27026	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0089706	biolink:NamedThing	L-ornithine transmembrane export from vacuole	The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane.	got7fsn_ti														biological_process											owl:Class	
CHEBI:58805	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29806	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005091	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045738	biolink:NamedThing	negative regulation of DNA repair	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair.	got7fsn_ti	down regulation of DNA repair|inhibition of DNA repair|down-regulation of DNA repair|downregulation of DNA repair													biological_process											owl:Class	
GO:0090296	biolink:NamedThing	regulation of mitochondrial DNA replication	Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.	got7fsn_ti	regulation of mitochondrial DNA synthesis						tb	2010-03-12T03:58:25Z						biological_process											owl:Class	
CHEBI:57326	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044372	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032312	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000679	biolink:NamedThing	positive regulation of transcription regulatory region DNA binding	Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.	got7fsn_ti							yaf	2011-05-09T03:28:17Z						biological_process											owl:Class	
UBERON:0001817	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35143	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28163	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50277	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016030	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001612	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046837	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57533	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901433	biolink:NamedThing	positive regulation of response to cycloalkane	Any process that activates or increases the frequency, rate or extent of response to cycloalkane.	got7fsn_ti	activation of response to cycloalkane|upregulation of response to cycloalkane|up regulation of response to cycloalkane|up-regulation of response to cycloalkane						tt	2012-10-01T21:03:26Z						biological_process											owl:Class	
GO:1900869	biolink:NamedThing	tatiopterin metabolic process	The chemical reactions and pathways involving tatiopterin.	got7fsn_ti	tatiopterin metabolism						tt	2012-06-12T04:43:57Z						biological_process											owl:Class	
CHEBI:60981	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009325	biolink:NamedThing	nitrate reductase complex	An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor.	got7fsn_ti														cellular_component											owl:Class	
CHEBI:26214	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905837	biolink:NamedThing	cellular response to triterpenoid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.	got7fsn_ti							sl	2017-01-17T19:37:44Z						biological_process											owl:Class	
GO:0071991	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:87792	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904334	biolink:NamedThing	heme import across plasma membrane	The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	heme assimilation						al	2015-06-11T16:56:21Z						biological_process											owl:Class	
GO:0045639	biolink:NamedThing	positive regulation of myeloid cell differentiation	Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.	got7fsn_ti	upregulation of myeloid cell differentiation|stimulation of myeloid cell differentiation|up regulation of myeloid cell differentiation|up-regulation of myeloid cell differentiation|activation of myeloid cell differentiation													biological_process											owl:Class	
GO:0005558	biolink:NamedThing	obsolete minor histocompatibility antigen	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	minor histocompatibility antigen				This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True				molecular_function											owl:Class	
CL:0002385	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_59897	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61414	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61697	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61910	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099633	biolink:NamedThing	protein localization to postsynaptic specialization membrane	A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density).	got7fsn_ti	protein localisation in postsynaptic specialization membrane													biological_process											owl:Class	
CHEBI:33563	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61079	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18005	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:66950	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30031	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000815	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001620	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002132	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0005024	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61345	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008897	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050647	biolink:NamedThing	5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Binding to 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.	got7fsn_ti	5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding													molecular_function											owl:Class	
GO:0005941	biolink:NamedThing	obsolete unlocalized protein complex	OBSOLETE. Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products.	got7fsn_ti	unlocalized protein complex				This term was made obsolete because it was originally intended only as a temporary parent for protein complex terms for which no more specific parents had been found. This term no longer has any children: All protein complex terms are is_a 'protein complex ; GO:0043234' and nearly all have been placed under parents to yield more specific paths traversing a part_of relationship. In other words, the term has been superseded by other terms and relationships in the cellular component ontology, and is no longer needed.					True				cellular_component											owl:Class	
GO:0060375	biolink:NamedThing	regulation of mast cell differentiation	Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	got7fsn_ti														biological_process											owl:Class	
GO:0002282	biolink:NamedThing	microglial cell activation involved in immune response	The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	got7fsn_ti	microglial cell activation during immune response													biological_process											owl:Class	
GO:0072473	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004882	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019173	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:3892	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000650	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046416	biolink:NamedThing	D-amino acid metabolic process	The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids.	got7fsn_ti	D-amino acid metabolism													biological_process											owl:Class	
UBERON:0004159	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000199	biolink:NamedThing	positive regulation of ribonucleoprotein complex localization	Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization.	got7fsn_ti	positive regulation of cellular ribonucleoprotein complex localization|positive regulation of ribonucleoprotein complex localisation|positive regulation of establishment and maintenance of ribonucleoprotein complex localization|positive regulation of RNP localization						mah	2010-10-26T10:35:55Z						biological_process											owl:Class	
GO:0010505	biolink:NamedThing	obsolete positive regulation of cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that increases the frequency or rate of cell cycle arrest in response to nitrogen starvation.	got7fsn_ti					This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.					True				biological_process											owl:Class	
GO:1904322	biolink:NamedThing	cellular response to forskolin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.	got7fsn_ti							sl	2015-06-10T19:01:33Z						biological_process											owl:Class	
CHEBI:29067	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001892	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:47878	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008367	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58429	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007054	biolink:NamedThing	spindle assembly involved in male meiosis I	The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.	got7fsn_ti	male meiosis I spindle assembly													biological_process											owl:Class	
GO:0032246	biolink:NamedThing	regulation of pyrimidine nucleoside transport	Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0090200	biolink:NamedThing	positive regulation of release of cytochrome c from mitochondria	Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.	got7fsn_ti					The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and positively regulate this process.		tb	2009-12-18T11:35:20Z						biological_process											owl:Class	
GO:0045355	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:GOCHE_50114	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150138	biolink:NamedThing	negative regulation of interleukin-37 production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production.	got7fsn_ti	negative regulation of interleukin-37 biosynthetic process						bc	2019-12-08T08:45:29Z						biological_process											owl:Class	
GO:0030403	biolink:NamedThing	obsolete collagenase 4 activity	OBSOLETE. Was not defined before being made obsolete.	got7fsn_ti	collagenase 4 activity|matrix metalloproteinase 18|MMP-18			GO:0004252	This term was made obsolete because it represents a gene product.					True				molecular_function											owl:Class	
GO:0090348	biolink:NamedThing	regulation of cellular organofluorine metabolic process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.	got7fsn_ti							tb	2010-06-02T10:36:42Z						biological_process											owl:Class	
GO:1904195	biolink:NamedThing	regulation of granulosa cell proliferation	Any process that modulates the frequency, rate or extent of granulosa cell proliferation.	got7fsn_ti							sl	2015-05-07T17:02:25Z						biological_process											owl:Class	
PO:0009067	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64641	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000574	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035373	biolink:NamedThing	chondroitin sulfate proteoglycan binding	Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.	got7fsn_ti							bf	2010-03-12T10:23:55Z						molecular_function											owl:Class	
GO:2000932	biolink:NamedThing	positive regulation of cellobiose metabolic process	Any process that activates or increases the frequency, rate or extent of cellobiose metabolic process.	got7fsn_ti	positive regulation of cellobiose metabolism						tt	2011-08-01T12:43:01Z						biological_process											owl:Class	
GO:0060354	biolink:NamedThing	negative regulation of cell adhesion molecule production	Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.	got7fsn_ti														biological_process											owl:Class	
PR:000007972	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048622	biolink:NamedThing	obsolete reproductive sporulation	OBSOLETE. The formation of reproductive spores.	got7fsn_ti	reproductive sporulation				This term was made obsolete because it was ambiguously defined and incorrectly placed in the ontology.					True				biological_process											owl:Class	
CHEBI:17984	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57484	biolink:NamedThing			got7fsn_ti																									owl:Class	
OIO:hasBroadSynonym	biolink:NamedThing	has_broad_synonym		got7fsn_ti																									owl:AnnotationProperty	
CHEBI:13392	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904622	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001592	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:16261	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000123	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22653	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045573	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090454	biolink:NamedThing	glutamate transmembrane import into vacuole	The directed movement of glutamate into the vacuole across the vacuolar membrane.	got7fsn_ti	vacuolar glutamate import						tb	2012-09-24T14:12:46Z						biological_process											owl:Class	
CHEBI:75431	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17573	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52447	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043192	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0006170	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061944	biolink:NamedThing	negative regulation of protein K48-linked ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.	got7fsn_ti							dph	2017-09-22T11:37:18Z						biological_process											owl:Class	
GO:1990219	biolink:NamedThing	obsolete positive regulation by symbiont of host protein levels	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it is a readout, and annotations should be made to more informative terms.		ml	2013-10-10T17:26:03Z		True				biological_process											owl:Class	
GO:0014713	biolink:NamedThing	negative regulation of branchiomeric skeletal muscle development	Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0099566	biolink:NamedThing	regulation of postsynaptic cytosolic calcium ion concentration	Any process that regulates the concentration of calcium in the postsynaptic cytosol.	got7fsn_ti	regulation of postsynaptic cytosolic calcium levels													biological_process											owl:Class	
GO:0042282	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:62938	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001579	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019451	biolink:NamedThing	L-cysteine catabolic process to pyruvate, using cysteine dioxygenase	The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).	got7fsn_ti	L-cysteine degradation to pyruvate, using cysteine dioxygenase|L-cysteine breakdown to pyruvate, using cysteine dioxygenase											MetaCyc:CYSTEINE-DEG-PWY		biological_process											owl:Class	
CHEBI:51963	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990886	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:73774	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001449	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50562	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005114	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000945	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075231	biolink:NamedThing	obsolete modulation of spore movement on or near host	OBSOLETE. Any process that modulates the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti					This term was obsoleted because it represented both a process and a location.					True				biological_process											owl:Class	
CHEBI:81567	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050723	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58690	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905794	biolink:NamedThing	response to puromycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.	got7fsn_ti	response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine						sl	2017-01-10T21:13:18Z						biological_process											owl:Class	
GO:0051605	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045391	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019578	biolink:NamedThing	aldaric acid biosynthetic process	The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.	got7fsn_ti	aldaric acid formation|aldaric acid anabolism|aldaric acid biosynthesis|aldaric acid synthesis													biological_process											owl:Class	
UBERON:0004129	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58950	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060450	biolink:NamedThing	positive regulation of hindgut contraction	Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.	got7fsn_ti														biological_process											owl:Class	
CHEBI:61109	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048420	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019462	biolink:NamedThing	glutamine catabolic process to fumarate, using glutaminase	The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2).	got7fsn_ti	glutamine degradation to fumarate, using glutaminase|glutamine breakdown to fumarate, using glutaminase|glutamate catabolic process to fumarate, using glutaminase											MetaCyc:GLUTAMINDEG-PWY		biological_process											owl:Class	
GO:0007027	biolink:NamedThing	negative regulation of axonemal microtubule depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.	got7fsn_ti	negative regulation of microtubule depolymerization in axoneme|axonemal microtubule stabilization													biological_process											owl:Class	
GO:0090182	biolink:NamedThing	regulation of secretion of lysosomal enzymes	Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.	got7fsn_ti							tb	2009-12-18T10:40:46Z						biological_process											owl:Class	
GO:1901739	biolink:NamedThing	regulation of myoblast fusion	Any process that modulates the frequency, rate or extent of myoblast fusion.	got7fsn_ti							rl	2013-01-11T20:23:50Z						biological_process											owl:Class	
CHEBI:62783	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045611	biolink:NamedThing	negative regulation of hemocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.	got7fsn_ti	down regulation of hemocyte differentiation|downregulation of hemocyte differentiation|down-regulation of hemocyte differentiation|inhibition of hemocyte differentiation|negative regulation of arthropod blood cell differentiation													biological_process											owl:Class	
CHEBI:64418	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072465	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:35243	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043944	biolink:NamedThing	negative regulation of asexual sporulation resulting in formation of a cellular spore	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.	got7fsn_ti														biological_process											owl:Class	
CHEBI:30617	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001621	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000006	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:78679	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24026	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_23530	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005472	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:36916	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58048	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904926	biolink:NamedThing	response to palmitoleic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.	got7fsn_ti							mr	2016-01-27T23:07:22Z						biological_process											owl:Class	
CHEBI:16688	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37554	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:6121	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052056	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57307	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043349	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1902304	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:50681	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21858	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030359	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:44800	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000021	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15379	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29748	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098589	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:67208	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000301	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905431	biolink:NamedThing	microcystin transport	The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							cvs	2016-09-13T23:15:51Z						biological_process											owl:Class	
GO:0042227	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:2000056	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58396	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22271	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001887	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28262	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990519	biolink:NamedThing	pyrimidine nucleotide import into mitochondrion	The process in which a pyrimidine nucleotide is transported across the mitochondrial inner membrane, into the mitochondrial matrix.	got7fsn_ti	mitochondrial pyrimidine nucleotide import						vw	2014-10-22T10:20:23Z						biological_process											owl:Class	
CHEBI:68624	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052143	biolink:NamedThing	obsolete chemotaxis on or near host involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	chemotaxis on or near host during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819			This term was obsoleted because it represents both a process and a location.					True				biological_process											owl:Class	
GO:0008850	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048399	biolink:NamedThing	regulation of intermediate mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification.	got7fsn_ti														biological_process											owl:Class	
GO:0003679	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046614	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052780	biolink:NamedThing	chitobiose metabolic process	The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.	got7fsn_ti							ai	2011-10-03T08:48:09Z						biological_process											owl:Class	
GO:0048271	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003080	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29118	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043694	biolink:NamedThing	monoterpene catabolic process	The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure.	got7fsn_ti	monoterpene catabolism													biological_process											owl:Class	
PR:000011194	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043350	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0140412	biolink:NamedThing	zinc:bicarbonate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) = zinc(in) + HCO3-(in).	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/18345					pg	2020-01-07T18:43:02Z						molecular_function											owl:Class	
CL:0000020	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002678	biolink:NamedThing	positive regulation of chronic inflammatory response	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response.	got7fsn_ti	stimulation of chronic inflammatory response|activation of chronic inflammatory response|up regulation of chronic inflammatory response|upregulation of chronic inflammatory response|up-regulation of chronic inflammatory response													biological_process											owl:Class	
UBERON:0002425	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:19702	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090029	biolink:NamedThing	negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.	got7fsn_ti							tb	2009-08-03T10:27:04Z						biological_process											owl:Class	
CHEBI:25036	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17378	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26878	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097327	biolink:NamedThing	response to antineoplastic agent	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.	got7fsn_ti							pr	2012-06-12T10:48:28Z						biological_process											owl:Class	
CL:0000607	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002291	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24846	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001971	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001661	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27338	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22907	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075242	biolink:NamedThing	negative regulation of zoospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.	got7fsn_ti														biological_process											owl:Class	
BFO:0000017	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052448	biolink:NamedThing	obsolete modulation by organism of ethylene levels in symbiont	OBSOLETE. The alteration by an organism of the levels of ethylene in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	modulation by organism of ethylene levels in symbiont				This term was made obsolete because it does not represent a real biological process.					True				biological_process											owl:Class	
GO:0032951	biolink:NamedThing	regulation of beta-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans.	got7fsn_ti	regulation of beta-glucan biosynthesis|regulation of beta-glucan formation|regulation of beta-glucan synthesis|regulation of beta-glucan anabolism													biological_process											owl:Class	
GO:0016736	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043193	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0070281	biolink:NamedThing	pyridoxamine binding	Binding to pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.	got7fsn_ti														molecular_function											owl:Class	
PR:000016052	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150070	biolink:NamedThing	regulation of arginase activity	Any process that modulates the frequency, rate or extent of arginase activity.	got7fsn_ti							bc	2018-07-25T09:17:30Z						biological_process											owl:Class	
GO:1901816	biolink:NamedThing	beta-zeacarotene metabolic process	The chemical reactions and pathways involving beta-zeacarotene.	got7fsn_ti	beta-zeacarotene metabolism						yaf	2013-01-22T10:42:03Z						biological_process											owl:Class	
SO:0002141	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019220	biolink:NamedThing	regulation of phosphate metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.	got7fsn_ti	regulation of phosphate metabolism													biological_process											owl:Class	
CHEBI:60963	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000282	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25614	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075314	biolink:NamedThing	regulation of basidium development	Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.	got7fsn_ti														biological_process											owl:Class	
CHEBI:26385	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17154	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22507	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009362	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:16708	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903975	biolink:NamedThing	regulation of glial cell migration	Any process that modulates the frequency, rate or extent of glial cell migration.	got7fsn_ti	regulation of glia cell migration						nc	2015-03-02T15:13:31Z						biological_process											owl:Class	
GO:0001151	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001657	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031636	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:27086	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015380	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905624	biolink:NamedThing	regulation of L-methionine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane.	got7fsn_ti							vw	2016-10-29T16:27:29Z						biological_process											owl:Class	
GO:0044243	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0000037	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0120154	biolink:NamedThing	negative regulation of ERBB4 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway.	got7fsn_ti							krc	2018-05-01T17:12:23Z						biological_process											owl:Class	
PR:000006909	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002664	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014910	biolink:NamedThing	regulation of smooth muscle cell migration	Any process that modulates the frequency, rate or extent of smooth muscle cell migration.	got7fsn_ti														biological_process											owl:Class	
GO:1905449	biolink:NamedThing	regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.	got7fsn_ti	regulation of Fc gamma receptor-dependent phagocytosis|regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|regulation of IgG-mediated phagocytosis|regulation of Fcgamma receptor-mediated phagocytosis						sl	2016-09-15T19:41:50Z						biological_process											owl:Class	
PO:0025121	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003846	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004171	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000449	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0005026	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043017	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:63736	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019669	biolink:NamedThing	anaerobic glycine catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP.	got7fsn_ti	glycine fermentation													biological_process											owl:Class	
CHEBI:15927	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18918	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002186	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004183	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0021908	biolink:NamedThing	retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.	got7fsn_ti	retinoic acid receptor signalling pathway in spinal cord anterior-posterior patterning													biological_process											owl:Class	
GO:0031292	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000777	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:28087	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043943	biolink:NamedThing	regulation of asexual sporulation resulting in formation of a cellular spore	Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.	got7fsn_ti														biological_process											owl:Class	
GO:0075250	biolink:NamedThing	negative regulation of aeciospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.	got7fsn_ti														biological_process											owl:Class	
GO:0005370	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PO:0004511	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001026	biolink:NamedThing	regulation of endothelial cell chemotaxis	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis.	got7fsn_ti							rl	2011-08-22T01:07:26Z						biological_process											owl:Class	
CHEBI:61442	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071457	biolink:NamedThing	cellular response to ozone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.	got7fsn_ti							mah	2009-12-16T04:45:59Z						biological_process											owl:Class	
UBERON:0003050	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:70723	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099632	biolink:NamedThing	protein transport within plasma membrane	A process in which protein is transported from one region of the plasma membrane to another.	got7fsn_ti														biological_process											owl:Class	
CHEBI:50383	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46195	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900164	biolink:NamedThing	nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.	got7fsn_ti	nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry|nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|nodal signaling of determination of left/right asymmetry in lateral mesoderm						bf	2012-03-08T02:58:39Z						biological_process											owl:Class	
GO:0099088	biolink:NamedThing	axonal transport of messenger ribonucleoprotein complex	The directed movement of a messenger ribonucleoprotein complex along microtubules in axons.	got7fsn_ti	axonal transport of mRNA RNP complex													biological_process											owl:Class	
GO:0070320	biolink:NamedThing	inward rectifier potassium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.	got7fsn_ti														molecular_function											owl:Class	
GO:1901883	biolink:NamedThing	4-hydroxycoumarin catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin.	got7fsn_ti	4-hydroxycoumarin catabolism|4-hydroxycoumarin degradation|4-hydroxycoumarin breakdown						ms	2013-02-06T14:05:54Z						biological_process											owl:Class	
UBERON:0005125	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61404	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64522	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64373	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58477	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:76150	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060916	biolink:NamedThing	mesenchymal cell proliferation involved in lung development	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	got7fsn_ti							dph	2009-09-18T11:50:17Z						biological_process											owl:Class	
GO:0046278	biolink:NamedThing	3,4-dihydroxybenzoate metabolic process	The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid).	got7fsn_ti	protocatechuate metabolic process|protocatechuate metabolism													biological_process											owl:Class	
UBERON:0007376	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098829	biolink:NamedThing	intestinal folate absorption	Uptake of folic into the blood by absorption from the small intestine.	got7fsn_ti														biological_process											owl:Class	
CHEBI:58057	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001759	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26073	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62461	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000099	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902714	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58635	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904726	biolink:NamedThing	regulation of replicative senescence	Any process that modulates the frequency, rate or extent of replicative senescence.	got7fsn_ti							rph	2015-10-14T13:11:24Z						biological_process											owl:Class	
PR:000003777	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001893	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004200	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030362	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000403	biolink:NamedThing	positive regulation of lymphocyte migration	Any process that activates or increases the frequency, rate or extent of lymphocyte migration.	got7fsn_ti							mah	2011-02-23T10:46:06Z						biological_process											owl:Class	
OBO:GOCHE_35623	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64124	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0061833	biolink:NamedThing	protein localization to tricellular tight junction	A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction.	got7fsn_ti														biological_process											owl:Class	
UBERON:0005308	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004209	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67153	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901673	biolink:NamedThing	regulation of mitotic spindle assembly	Any process that modulates the frequency, rate or extent of mitotic spindle assembly.	got7fsn_ti	regulation of spindle assembly involved in mitosis						al	2012-11-22T09:50:00Z						biological_process											owl:Class	
CHEBI:31355	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060145	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:48030	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006966	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0036070	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072215	biolink:NamedThing	regulation of metanephros development	Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.	got7fsn_ti														biological_process											owl:Class	
GO:1902721	biolink:NamedThing	negative regulation of prolactin secretion	Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion.	got7fsn_ti	down-regulation of prolactin secretion|inhibition of prolactin secretion|down regulation of prolactin secretion|downregulation of prolactin secretion						mr	2014-02-24T16:09:28Z						biological_process											owl:Class	
CL:0000718	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905087	biolink:NamedThing	positive regulation of bioluminescence	Any process that activates or increases the frequency, rate or extent of bioluminescence.	got7fsn_ti	activation of bioluminescence|upregulation of bioluminescence|up-regulation of bioluminescence|up regulation of bioluminescence						rph	2016-03-29T07:51:27Z						biological_process											owl:Class	
UBERON:0002257	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000091	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:49709	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001473	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007242	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003501	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014711	biolink:NamedThing	regulation of branchiomeric skeletal muscle development	Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.	got7fsn_ti														biological_process											owl:Class	
GO:0019992	biolink:NamedThing	diacylglycerol binding	Binding to a diacylglycerol, a diester of glycerol and two fatty acids.	got7fsn_ti														molecular_function											owl:Class	
GO:0075257	biolink:NamedThing	positive regulation of teliospore formation	Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.	got7fsn_ti														biological_process											owl:Class	
GO:0075034	biolink:NamedThing	obsolete nuclear division involved in appressorium formation	OBSOLETE. The process in which nuclear division occurs within a symbiont spore that contributes to appressorium formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	nuclear division involved in appressorium formation on or near host|nuclear division during appressorium formation on or near host	https://github.com/geneontology/go-ontology/issues/21923			The reason for obsoletion is that there is no evidence that this process exists.					True				biological_process											owl:Class	
CHEBI:64711	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002639	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001003	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033128	biolink:NamedThing	negative regulation of histone phosphorylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.	got7fsn_ti														biological_process											owl:Class	
GO:0110122	biolink:NamedThing	myotube cell migration	The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse.	got7fsn_ti							kmv	2018-08-22T20:58:09Z						biological_process											owl:Class	
GO:1900503	biolink:NamedThing	regulation of cellulosome assembly	Any process that modulates the frequency, rate or extent of cellulosome assembly.	got7fsn_ti							tt	2012-05-02T03:58:15Z						biological_process											owl:Class	
CHEBI:28554	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000005869	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052073	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:61393	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018921	biolink:NamedThing	3-hydroxybenzyl alcohol metabolic process	The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum.	got7fsn_ti	3-hydroxybenzyl alcohol metabolism											UM-BBD_pathwayID:mcr		biological_process											owl:Class	
CHEBI:16750	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30212	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:143285	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64534	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140192	biolink:NamedThing	regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.	got7fsn_ti							pg	2018-02-15T19:06:38Z						biological_process											owl:Class	
PR:000001153	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4767	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014857	biolink:NamedThing	regulation of skeletal muscle cell proliferation	Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation.	got7fsn_ti														biological_process											owl:Class	
CHEBI:23457	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002967	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003364	biolink:NamedThing	lamellipodium assembly involved in mesendodermal cell migration	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell.	got7fsn_ti							dph	2009-12-08T04:46:39Z						biological_process											owl:Class	
UBERON:0010302	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004128	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29034	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000152	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903768	biolink:NamedThing	taste receptor complex	A protein complex which is capable of taste receptor activity.	got7fsn_ti							rl	2014-12-22T16:53:45Z						cellular_component											owl:Class	
GO:0046320	biolink:NamedThing	regulation of fatty acid oxidation	Any process that modulates the frequency, rate or extent of fatty acid oxidation.	got7fsn_ti														biological_process											owl:Class	
UBERON:0001021	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28997	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060559	biolink:NamedThing	positive regulation of calcidiol 1-monooxygenase activity	Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.	got7fsn_ti							dph	2009-04-13T02:57:28Z						biological_process											owl:Class	
UBERON:0006955	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002597	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0014895	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57865	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990821	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:77847	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0006341	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18227	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60903	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900922	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:24103	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005101	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64243	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37684	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46261	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_50113	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64220	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:77659	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050761	biolink:NamedThing	depsipeptide metabolic process	The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.	got7fsn_ti	depsipeptide metabolism													biological_process											owl:Class	
GO:0010779	biolink:NamedThing	meiotic DNA repair synthesis involved in meiotic gene conversion	The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.	got7fsn_ti														biological_process											owl:Class	
GO:1903160	biolink:NamedThing	obsolete nickel cation transmembrane transporter activity involved in nickel cation import into cell	OBSOLETE. Any nickel cation transmembrane transporter activity that is involved in nickel cation import into cell.	got7fsn_ti	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity involved in nickel cation import into cell|nickel cation transmembrane transporter activity involved in nickel cation import into cell				This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:33Z		True				molecular_function											owl:Class	
GO:0000788	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:47978	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0097292	biolink:NamedThing	XMP metabolic process	The chemical reactions and pathways involving XMP, xanthosine monophosphate.	got7fsn_ti	XMP metabolism						pr	2012-04-26T09:51:16Z						biological_process											owl:Class	
CHEBI:23378	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033387	biolink:NamedThing	putrescine biosynthetic process from ornithine	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.	got7fsn_ti	putrescine formation from ornithine|putrescine synthesis from ornithine|putrescine anabolism from ornithine|putrescine biosynthesis from ornithine													biological_process											owl:Class	
GO:0034759	biolink:NamedThing	regulation of iron ion transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.	got7fsn_ti	regulation of transmembrane Fe transport|regulation of transmembrane iron ion transport|regulation of iron ion membrane transport|regulation of transmembrane iron transport													biological_process											owl:Class	
GO:0014808	biolink:NamedThing	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.	got7fsn_ti	release of sequestered calcium ion by sarcoplasmic reticulum into cytosol													biological_process											owl:Class	
GO:0120018	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000006165	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000546	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051202	biolink:NamedThing	phytochromobilin metabolic process	The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity.	got7fsn_ti	phytochromobilin metabolism													biological_process											owl:Class	
UBERON:0001333	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044453	biolink:NamedThing	obsolete nuclear membrane part	OBSOLETE. Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells.	got7fsn_ti					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0031965				True				cellular_component											owl:Class	
GO:0052071	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:2000020	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18282	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000032	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22712	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045952	biolink:NamedThing	regulation of juvenile hormone catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.	got7fsn_ti	regulation of juvenile hormone degradation|regulation of juvenile hormone breakdown|regulation of juvenile hormone catabolism													biological_process											owl:Class	
GO:0140612	biolink:NamedThing	DNA damage sensor activity	A molecule that recognises toxic DNA structures, for example, double-strand breaks or collapsed replication forks, and initiates a signalling response.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/19051					pg	2021-03-03T18:11:17Z						molecular_function											owl:Class	
GO:0050430	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:70773	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002280	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045789	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:6801	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001489	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58249	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006416	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0150113	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0000084	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17790	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0055024	biolink:NamedThing	regulation of cardiac muscle tissue development	Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.	got7fsn_ti	regulation of heart muscle development													biological_process											owl:Class	
CHEBI:58404	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072636	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0007013	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1904735	biolink:NamedThing	regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	Any process that modulates the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.	got7fsn_ti							lb	2015-10-15T08:14:51Z						biological_process											owl:Class	
PR:000001442	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:79071	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045383	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019210	biolink:NamedThing	kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a kinase.	got7fsn_ti														molecular_function											owl:Class	
OBO:GOCHE_35523	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009043	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:61295	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030873	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:59904	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001327	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140646	biolink:NamedThing	negative regulation of pre-B cell receptor expression	Any process that stops, prevents or reduces the frequency, rate or extent of the process leading up to expression of the pre-B cell receptor on the surface of pre-B cells.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/20121					pg	2021-05-19T10:50:53Z						biological_process											owl:Class	
GO:0061271	biolink:NamedThing	mesenchymal to epithelial transition involved in mesonephric renal vesicle formation	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.	got7fsn_ti							dph	2010-08-30T03:26:30Z						biological_process											owl:Class	
CHEBI:30879	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002595	biolink:NamedThing	regulation of antigen processing and presentation of peptide antigen via MHC class Ib	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.	got7fsn_ti	regulation of peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
CHEBI:26977	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002101	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22315	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000697	biolink:NamedThing	negative regulation of epithelial cell differentiation involved in kidney development	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development.	got7fsn_ti							bf	2011-05-16T04:23:55Z						biological_process											owl:Class	
CHEBI:59640	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001225	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000445	biolink:NamedThing	THO complex part of transcription export complex	The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits.	got7fsn_ti	THO complex part of TREX complex													cellular_component											owl:Class	
UBERON:0004340	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003063	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006174	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005176	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000356	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006825	biolink:NamedThing	copper ion transport	The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti														biological_process											owl:Class	
GO:0002598	biolink:NamedThing	regulation of antigen processing and presentation of lipid antigen via MHC class Ib	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.	got7fsn_ti	regulation of lipid antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
CHEBI:37163	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:175901	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019311	biolink:NamedThing	sorbose metabolic process	The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.	got7fsn_ti	sorbose metabolism													biological_process											owl:Class	
CHEBI:36233	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002378	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001215	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:17310	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000011459	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002423	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:77860	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30409	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16133	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046578	biolink:NamedThing	regulation of Ras protein signal transduction	Any process that modulates the frequency, rate or extent of Ras protein signal transduction.	got7fsn_ti														biological_process											owl:Class	
GO:0060563	biolink:NamedThing	neuroepithelial cell differentiation	The process in which epiblast cells acquire specialized features of neuroepithelial cells.	got7fsn_ti							dph	2009-04-29T01:50:05Z						biological_process											owl:Class	
CHEBI:65004	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000173	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001882	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060222	biolink:NamedThing	regulation of retinal cone cell fate commitment	Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.	got7fsn_ti														biological_process											owl:Class	
CL:0000896	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16689	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63299	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64530	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010200	biolink:NamedThing	response to chitin	A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0051842	biolink:NamedThing	obsolete evasion or tolerance of symbiont immune response	OBSOLETE. Any process, either active or passive, by which an organism avoids the effects of the symbiont organism's immune response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	got7fsn_ti	evasion or tolerance of symbiont immune response|immune evasion				This term was made obsolete because it does not represent a valid biological process that occurs in nature.					True				biological_process											owl:Class	
UBERON:0001041	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58187	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:78485	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005065	biolink:NamedThing	obsolete heterotrimeric G-protein	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	heterotrimeric G-protein			GO:0005834	This term was made obsolete because it represents a cellular component and not a molecular function.					True				molecular_function											owl:Class	
CL:1000409	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052295	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0000295	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002451	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001718	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26386	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46081	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000115	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16536	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18254	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64633	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26442	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27252	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032903	biolink:NamedThing	regulation of nerve growth factor production	Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF).	got7fsn_ti	regulation of beta-nerve growth factor production|regulation of NGF production													biological_process											owl:Class	
CL:0000654	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019568	biolink:NamedThing	arabinose catabolic process	The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.	got7fsn_ti	arabinose catabolism|arabinose degradation|arabinose breakdown													biological_process											owl:Class	
CL:0000817	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004708	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000066	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26834	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000024067	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008814	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22289	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17172	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001113	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15595	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901473	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:26347	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000946	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33568	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0012001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035007	biolink:NamedThing	regulation of melanization defense response	Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.	got7fsn_ti	regulation of melanization defence response													biological_process											owl:Class	
GO:1904008	biolink:NamedThing	response to monosodium glutamate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus.	got7fsn_ti							sl	2015-03-06T18:26:34Z						biological_process											owl:Class	
CHEBI:63954	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35693	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:43572	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000661	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033684	biolink:NamedThing	regulation of luteinizing hormone secretion	Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.	got7fsn_ti														biological_process											owl:Class	
CL:0000730	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007334	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0046035	biolink:NamedThing	CMP metabolic process	The chemical reactions and pathways involving CMP, cytidine monophosphate.	got7fsn_ti	CMP metabolism													biological_process											owl:Class	
CHEBI:61111	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001225	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27617	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000609	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006795	biolink:NamedThing	regulation of phosphorus utilization	Any process that modulates the frequency, rate or extent of phosphorus utilization.	got7fsn_ti														biological_process											owl:Class	
GO:0060244	biolink:NamedThing	negative regulation of cell proliferation involved in contact inhibition	Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density.	got7fsn_ti														biological_process											owl:Class	
GO:0150161	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0009198	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000008942	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000669	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001796	biolink:NamedThing	regulation of type IIa hypersensitivity	Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response.	got7fsn_ti														biological_process											owl:Class	
CHEBI:27533	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007204	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016017	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0000912	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070133	biolink:NamedThing	negative regulation of mitochondrial translational initiation	Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.	got7fsn_ti	negative regulation of mitochondrial translation initiation													biological_process											owl:Class	
UBERON:0000922	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28384	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046476	biolink:NamedThing	glycosylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.	got7fsn_ti	glycosylceramide formation|glycosylceramide biosynthesis|glycosylceramide anabolism|glycosylceramide synthesis													biological_process											owl:Class	
CHEBI:36674	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140353	biolink:NamedThing	lipid export from cell	The directed movement of a lipid from a cell, into the extracellular region.	got7fsn_ti	lipid efflux						pg	2019-05-22T11:33:07Z						biological_process											owl:Class	
CHEBI:5254	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17636	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63161	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28909	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002730	biolink:NamedThing	regulation of dendritic cell cytokine production	Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.	got7fsn_ti														biological_process											owl:Class	
CHEBI:28579	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902316	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0000939	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:34905	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001474	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38201	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000396	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043146	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:64816	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000083	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001265	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990236	biolink:NamedThing	proteasome core complex import into nucleus	The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus.	got7fsn_ti							rb	2013-11-14T23:27:24Z						biological_process											owl:Class	
CHEBI:25905	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016952	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:17234	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903130	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051579	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0072618	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010762	biolink:NamedThing	regulation of fibroblast migration	Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.	got7fsn_ti	regulation of fibroblast cell migration													biological_process											owl:Class	
CHEBI:61314	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075297	biolink:NamedThing	negative regulation of ascospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.	got7fsn_ti														biological_process											owl:Class	
UBERON:0003890	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:74252	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26388	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006440	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:16724	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63184	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043927	biolink:NamedThing	exonucleolytic nuclear-transcribed mRNA catabolic process involved in endonucleolytic cleavage-dependent decay	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap.	got7fsn_ti														biological_process											owl:Class	
UBERON:0001840	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000002107	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58193	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57416	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075252	biolink:NamedThing	regulation of uredospore formation	Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.	got7fsn_ti	regulation of ureidospore formation													biological_process											owl:Class	
GO:0042999	biolink:NamedThing	regulation of Golgi to plasma membrane CFTR protein transport	Any process that modulates the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.	got7fsn_ti														biological_process											owl:Class	
CHEBI:26446	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0011006	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000825	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63191	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:14314	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045533	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:19260	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33838	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002524	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005110	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67246	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044254	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001091	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004134	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018552	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:27354	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032850	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010820	biolink:NamedThing	positive regulation of T cell chemotaxis	Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
PO:0020090	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000136	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000923	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001132	biolink:NamedThing	methane biosynthetic process from 3-(methylthio)propionic acid	The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid.	got7fsn_ti							jl	2011-10-13T12:19:33Z						biological_process											owl:Class	
GO:0016424	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006570	biolink:NamedThing	tyrosine metabolic process	The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.	got7fsn_ti	tyrosine metabolism											Wikipedia:Tyrosine|UM-BBD_pathwayID:tyr		biological_process											owl:Class	
CHEBI:73690	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043928	biolink:NamedThing	exonucleolytic catabolism of deadenylated mRNA	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.	got7fsn_ti														biological_process											owl:Class	
CHEBI:17968	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29021	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3766	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001736	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000084	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28302	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64502	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36976	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:9160	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000182	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000996	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045318	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001103	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26399	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0009001	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007239	biolink:NamedThing	obsolete activation of Hog1	OBSOLETE. (Was not defined before being made obsolete).	got7fsn_ti	activation of Hog1				This term was made obsolete because it contains gene product and species specific information.					True				biological_process											owl:Class	
CHEBI:22918	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075140	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090662	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:32372	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:71501	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17108	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004016	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046387	biolink:NamedThing	deoxyribose 1,5-bisphosphate metabolic process	The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.	got7fsn_ti	deoxyribose 1,5-bisphosphate metabolism													biological_process											owl:Class	
GO:0070539	biolink:NamedThing	linoleic acid binding	Binding to linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.	got7fsn_ti														molecular_function											owl:Class	
UBERON:0005063	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28892	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000019	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27380	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000820	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:47896	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075163	biolink:NamedThing	obsolete positive regulation of G-protein beta subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	positive regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host				This term was obsoleted because there is no evidence that this process exists.					True				biological_process											owl:Class	
CHEBI:61336	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58199	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052087	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016965	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006454	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:30477	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18022	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044502	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016609	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0000928	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:84123	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35740	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59825	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_25442	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64475	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001646	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000005870	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16235	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042529	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0000751	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35008	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26393	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075052	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000013164	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903805	biolink:NamedThing	L-valine import across plasma membrane	The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol.	got7fsn_ti	L-valine import into cell|valine import						tb	2012-09-24T14:28:58Z			GO:0090468			biological_process											owl:Class	
CHEBI:15409	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006028	biolink:NamedThing	galactosaminoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.	got7fsn_ti	galactosaminoglycan catabolism|galactosaminoglycan breakdown|galactosaminoglycan degradation													biological_process											owl:Class	
CL:0000842	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64120	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0036229	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075246	biolink:NamedThing	negative regulation of oospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.	got7fsn_ti														biological_process											owl:Class	
GO:0005719	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002491	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044711	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0002284	biolink:NamedThing	myeloid dendritic cell differentiation involved in immune response	The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.	got7fsn_ti	myeloid dendritic cell differentiation during immune response													biological_process											owl:Class	
CHEBI:28304	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25409	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044712	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58367	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000016301	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26995	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52289	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009030	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000382	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005097	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25903	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37396	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007892	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18296	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019632	biolink:NamedThing	shikimate metabolic process	The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.	got7fsn_ti	shikimate metabolism													biological_process											owl:Class	
CL:0002539	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60761	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60562	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35190	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010563	biolink:NamedThing	negative regulation of phosphorus metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.	got7fsn_ti														biological_process											owl:Class	
UBERON:0002264	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072613	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0010819	biolink:NamedThing	regulation of T cell chemotaxis	Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.	got7fsn_ti														biological_process											owl:Class	
GO:0000205	biolink:NamedThing	obsolete activation of MAPK during sporulation (sensu Saccharomyces)	OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	got7fsn_ti	activation of MAPK during sporulation (sensu Saccharomyces)				This term was made obsolete because it is a gene product specific term.					True				biological_process											owl:Class	
CHEBI:57706	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:77828	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0055033	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:23086	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032128	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:72949	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043342	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:65228	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000002198	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000608	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002559	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010080	biolink:NamedThing	regulation of floral meristem growth	Any process involved in maintaining the size and shape of a floral meristem.	got7fsn_ti	regulation of floral meristem size													biological_process											owl:Class	
CHEBI:16905	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005090	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052296	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:17898	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15889	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:133673	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:51354	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0023014	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:77506	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900515	biolink:NamedThing	regulation of xylose catabolic process to ethanol	Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol.	got7fsn_ti	regulation of xylose catabolism to ethanol						tt	2012-05-02T04:09:07Z						biological_process											owl:Class	
CHEBI:24898	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0098545	biolink:NamedThing	maintenance of protein complex location in cytoplasm	Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.	got7fsn_ti							dos	2013-11-15T20:49:15Z						biological_process											owl:Class	
GO:0030833	biolink:NamedThing	regulation of actin filament polymerization	Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.	got7fsn_ti	regulation of actin polymerization													biological_process											owl:Class	
GO:0006156	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:62776	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905780	biolink:NamedThing	regulation of phosphatidylserine exposure on apoptotic cell surface	Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.	got7fsn_ti	regulation of externalization of phosphatidylserine						kmv	2017-01-04T15:18:52Z						biological_process											owl:Class	
GO:0043868	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0048429	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003089	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043561	biolink:NamedThing	regulation of translational initiation in response to osmotic stress	Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	got7fsn_ti														biological_process											owl:Class	
GO:0015302	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002320	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1900123	biolink:NamedThing	regulation of nodal receptor complex assembly	Any process that modulates the frequency, rate or extent of nodal receptor complex assembly.	got7fsn_ti	regulation of nodal receptor complex formation|regulation of ActRIIB.ALK4.EGF-CFC complex formation						bf	2012-02-22T04:21:49Z						biological_process											owl:Class	
GO:0016141	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:64704	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:45075	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:48863	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28869	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:51277	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042523	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2000626	biolink:NamedThing	negative regulation of miRNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process.	got7fsn_ti	negative regulation of microRNA catabolic process						dph	2011-04-18T03:46:39Z						biological_process											owl:Class	
PR:000006267	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001133	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23872	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64705	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:2001470	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043201	biolink:NamedThing	response to leucine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.	got7fsn_ti														biological_process											owl:Class	
UBERON:0009919	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052266	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000107	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28934	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000315	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001091	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33822	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001369	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002602	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000188	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PO:0000042	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000140	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000925	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000012059	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57288	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009008	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33709	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:149509	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002028	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24250	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034244	biolink:NamedThing	negative regulation of transcription elongation from RNA polymerase II promoter	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.	got7fsn_ti	negative regulation of RNA elongation from RNA polymerase II promoter|negative regulation of gene-specific transcription elongation from RNA polymerase II promoter										GO:0090041			biological_process											owl:Class	
GO:0005525	biolink:NamedThing	GTP binding	Binding to GTP, guanosine triphosphate.	got7fsn_ti												Reactome:R-HSA-167429		molecular_function											owl:Class	
GO:0016044	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:142058	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005134	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000147	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3259	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25805	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001908	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005066	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:40968	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35785	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24337	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004122	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5533	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:8028	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0080052	biolink:NamedThing	response to histidine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.	got7fsn_ti														biological_process											owl:Class	
CHEBI:28063	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000127	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60978	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008588	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:2000440	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001635	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58304	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62764	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:48999	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904502	biolink:NamedThing	regulation of lipophagy	Any process that modulates the frequency, rate or extent of lipophagy.	got7fsn_ti							dph	2015-07-24T11:37:12Z						biological_process											owl:Class	
OBO:OBA_0000057	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019274	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0098972	biolink:NamedThing	anterograde dendritic transport of mitochondrion	The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body.	got7fsn_ti														biological_process											owl:Class	
CHEBI:26395	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57761	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001132	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075327	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1905658	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:78903	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001962	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000731	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000784	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63739	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15396	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008382	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001720	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16510	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010946	biolink:NamedThing	regulation of meiotic joint molecule formation	Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.	got7fsn_ti							tb	2009-04-27T09:46:23Z						biological_process											owl:Class	
UBERON:0005106	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:383703	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61194	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032380	biolink:NamedThing	regulation of intracellular sterol transport	Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.	got7fsn_ti														biological_process											owl:Class	
CHEBI:64629	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018381	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002137	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18233	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28697	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17600	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35340	biolink:NamedThing			got7fsn_ti																									owl:Class	
OIO:is_class_level	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
UBERON:0001900	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:53387	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003897	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0000169	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59497	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0014912	biolink:NamedThing	negative regulation of smooth muscle cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.	got7fsn_ti														biological_process											owl:Class	
GO:0071937	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0060192	biolink:NamedThing	negative regulation of lipase activity	Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.	got7fsn_ti														biological_process											owl:Class	
GO:0043395	biolink:NamedThing	heparan sulfate proteoglycan binding	Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.	got7fsn_ti	heparin proteoglycan binding													molecular_function											owl:Class	
GO:0071397	biolink:NamedThing	cellular response to cholesterol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.	got7fsn_ti							mah	2009-12-11T04:39:31Z						biological_process											owl:Class	
UBERON:0002165	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:40	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4903	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000181	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30613	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001105	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0055030	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001004	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008913	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004202	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042235	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002129	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33704	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60242	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046412	biolink:NamedThing	phenylmercury acetate metabolic process	The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.	got7fsn_ti	phenylmercury acetate metabolism													biological_process											owl:Class	
CHEBI:16602	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000802	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000013743	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24536	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002435	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:51149	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003922	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57292	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30313	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003761	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:17660	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002100	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045308	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0000058	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:79081	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033297	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0001209	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0012478	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0010007	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000037070	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58326	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035926	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0043058	biolink:NamedThing	regulation of backward locomotion	Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism.	got7fsn_ti														biological_process											owl:Class	
GO:0046742	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:5417	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57485	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003927	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:44423	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010526	biolink:NamedThing	negative regulation of transposition, RNA-mediated	Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.	got7fsn_ti														biological_process											owl:Class	
GO:0055107	biolink:NamedThing	Golgi to secretory granule transport	The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex.	got7fsn_ti														biological_process											owl:Class	
GO:0006976	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000124	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64397	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38755	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010525	biolink:NamedThing	regulation of transposition, RNA-mediated	Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.	got7fsn_ti														biological_process											owl:Class	
CHEBI:78741	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002168	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000656	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009286	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0045364	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006681	biolink:NamedThing	galactosylceramide metabolic process	The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.	got7fsn_ti	galactosylceramide metabolism													biological_process											owl:Class	
UBERON:0001343	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17231	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031198	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0015353	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0006770	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005084	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:24175	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37941	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045001	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019951	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:3375	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001225	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000106	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0006697	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57345	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045811	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0036459	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0007247	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36982	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22480	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002043	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043432	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0090466	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052277	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58339	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000010882	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000358	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005075	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0106311	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0012075	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030260	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0050874	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:9150	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020101	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23673	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16007	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57920	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001806	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150125	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:17594	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000055	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64090	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33853	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29990	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903410	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052669	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:46765	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025406	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010772	biolink:NamedThing	meiotic DNA recombinase assembly involved in reciprocal meiotic recombination	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	got7fsn_ti														biological_process											owl:Class	
UBERON:0004146	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003381	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001193	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000228	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26935	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045011	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:15710	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042607	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:51349	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000678	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016096	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:60253	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:2000940	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042449	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:33542	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46951	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57931	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:19257	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009071	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:39027	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29014	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002673	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60479	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001130	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4056	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1903834	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0071146	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0075323	biolink:NamedThing	positive regulation of oomycete sporangium development	Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.	got7fsn_ti														biological_process											owl:Class	
CL:0010022	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004145	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17336	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1905834	biolink:NamedThing	response to pyrimidine ribonucleotide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.	got7fsn_ti							sl	2017-01-17T19:23:59Z						biological_process											owl:Class	
GO:0045731	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:9688	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048130	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:167605	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000710	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16482	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002642	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:22651	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020030	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000709	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0033018	biolink:NamedThing	sarcoplasmic reticulum lumen	The volume enclosed by the membranes of the sarcoplasmic reticulum.	got7fsn_ti														cellular_component											owl:Class	
UBERON:0005323	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64543	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016876	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:64450	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000236	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30200	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38697	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000192	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33234	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000050	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000230	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016549	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003085	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000816	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000216	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901454	biolink:NamedThing	regulation of response to toluene	Any process that modulates the frequency, rate or extent of response to toluene.	got7fsn_ti							tt	2012-10-02T14:22:17Z						biological_process											owl:Class	
UBERON:0001155	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:80308	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000494	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004426	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0002671	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051040	biolink:NamedThing	regulation of calcium-independent cell-cell adhesion	Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.	got7fsn_ti														biological_process											owl:Class	
GO:0042411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57586	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051772	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001645	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58065	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042682	biolink:NamedThing	regulation of compound eye cone cell fate specification	Any process that mediates the specification of a cell into a compound eye cone cell.	got7fsn_ti											GO:0042681			biological_process											owl:Class	
GO:1990954	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:6495	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18287	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000099	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0008011	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004864	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28826	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001199	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003916	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30413	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:8273	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17698	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:86026	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009596	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57540	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24278	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16763	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051532	biolink:NamedThing			got7fsn_ti										True															owl:Class	
SO:0002234	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003104	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030675	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0004724	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:63534	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902464	biolink:NamedThing	regulation of histone H3-K27 trimethylation	Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation.	got7fsn_ti							krc	2013-10-22T14:58:55Z						biological_process											owl:Class	
CHEBI:28398	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67016	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60951	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21208	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000453	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016619	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052400	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:22632	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002828	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008425	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67026	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15343	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16918	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002355	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016588	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PO:0000191	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016947	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0051890	biolink:NamedThing	regulation of cardioblast differentiation	Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	got7fsn_ti														biological_process											owl:Class	
CHEBI:60815	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001088	biolink:NamedThing	trisaccharide transport	The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	got7fsn_ti							jl	2011-09-21T12:59:46Z						biological_process											owl:Class	
CL:1001503	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150114	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PO:0009066	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043492	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003704	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000162	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045126	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:35397	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_26672	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:74338	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001134	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006917	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000011406	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0007106	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37671	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:CARO_0000003	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002206	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58436	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15882	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0018236	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0030477	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001630	biolink:NamedThing			got7fsn_ti																									owl:Class	
DDANAT:0000413	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64398	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64610	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000151	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003062	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0003757	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000128	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61265	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002138	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25029	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17634	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57403	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18379	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002490	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26333	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58192	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1904455	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57735	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000033	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000784	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0052418	biolink:NamedThing	obsolete metabolism by organism of protein in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within a second organism, where the two organisms are in a symbiotic interaction.	got7fsn_ti	metabolism by organism of protein in other organism during symbiotic interaction				This term was obsoleted because it represents an unnecessary grouping class.					True				biological_process											owl:Class	
GO:1990041	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:25213	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:79516	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001842	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001005	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:39127	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002682	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17950	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0010010	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57371	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001145	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:63067	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002450	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29744	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0008003	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001945	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:20140	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000000017	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33641	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007497	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:6457	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57491	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57369	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64508	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902598	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0005317	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:26986	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28494	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1902580	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019840	biolink:NamedThing	isoprenoid binding	Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	got7fsn_ti														molecular_function											owl:Class	
CHEBI:26004	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000786	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58053	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0031046	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:35330	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015536	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:25179	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57476	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000221	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0010323	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044708	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0008367	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000715	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006759	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0006695	biolink:NamedThing			got7fsn_ti																									owl:Class	
OIO:is_metadata_tag	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
GO:0015201	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000002201	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045078	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0017091	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:28800	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16052	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004180	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1001434	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61481	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005313	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005320	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000155	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16961	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008561	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:24835	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1901329	biolink:NamedThing	regulation of odontoblast differentiation	Any process that modulates the frequency, rate or extent of odontoblast differentiation.	got7fsn_ti							hjd	2012-08-31T16:50:05Z						biological_process											owl:Class	
CHEBI:66916	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18211	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032851	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008632	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:35063	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:456216	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:71542	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17164	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16794	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000927	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:28460	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005089	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0070660	biolink:NamedThing	inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration	Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.	got7fsn_ti							mah	2009-05-28T04:24:23Z						biological_process											owl:Class	
GO:0060517	biolink:NamedThing	epithelial cell proliferation involved in prostatic bud elongation	The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud.	got7fsn_ti														biological_process											owl:Class	
PR:000001383	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62805	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000004978	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000402	biolink:NamedThing	negative regulation of lymphocyte migration	Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.	got7fsn_ti							mah	2011-02-23T10:45:47Z						biological_process											owl:Class	
UBERON:0007844	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000072	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000031	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4806	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000039	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001711	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001153	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60952	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002949	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000025	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009005	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0030676	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:30839	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001254	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050705	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0019582	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:17300	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000011116	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0140636	biolink:NamedThing	copper import into the mitochondrion	The process in which copper is transported from the cytosol into the mitochondrial matrix.	got7fsn_ti		https://github.com/geneontology/go-ontology/issues/21294					pg	2021-04-14T09:59:21Z						biological_process											owl:Class	
UBERON:0000017	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5686	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001128	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57597	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23115	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33848	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006472	biolink:NamedThing			got7fsn_ti										True															owl:Class	
rdfs:label	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
CHEBI:27941	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001218	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0086037	biolink:NamedThing	P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell.	got7fsn_ti							tb	2011-11-11T03:33:44Z						molecular_function											owl:Class	
CHEBI:64744	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000029	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002351	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002298	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:167637	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35371	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001290	biolink:NamedThing			got7fsn_ti																									owl:Class	
OIO:hasRelatedSynonym	biolink:NamedThing	has_related_synonym		got7fsn_ti																									owl:AnnotationProperty	
PO:0020043	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:145992	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007012	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003051	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000924	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0014403	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0060546	biolink:NamedThing	negative regulation of necroptotic process	Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.	got7fsn_ti	negative regulation of necroptosis						dph	2009-04-13T01:49:36Z						biological_process											owl:Class	
CHEBI:62945	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18303	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17026	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0007410	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000000046	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:9470	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045529	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:32832	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043352	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:46895	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16037	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28328	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001785	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001426	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004189	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000038	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26911	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23897	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_35476	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57990	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58223	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034747	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0000827	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000009978	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:19950	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001565	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000014544	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000010818	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25519	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000000028	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009282	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57308	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:9516	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:85543	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002979	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000069	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005088	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35492	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2001198	biolink:NamedThing	regulation of dendritic cell differentiation	Any process that modulates the frequency, rate or extent of dendritic cell differentiation.	got7fsn_ti							yaf	2011-11-04T02:01:27Z						biological_process											owl:Class	
CHEBI:61557	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000039	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:132988	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62780	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002367	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002019	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58224	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18222	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002030	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61057	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001993	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61360	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0006038	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58462	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000071	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22633	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006189	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000003652	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63300	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32382	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002103	biolink:NamedThing			got7fsn_ti																									owl:Class	
OIO:http://purl.org/dc/terms/source	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
CHEBI:57623	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052532	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003983	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24814	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57287	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046822	biolink:NamedThing	regulation of nucleocytoplasmic transport	Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.	got7fsn_ti														biological_process											owl:Class	
CHEBI:17562	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0011103	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072018	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58349	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001183	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:4000164	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000002112	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35998	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26558	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000011	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000955	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0019195	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005092	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:77932	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15775	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008867	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24943	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000217	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001538	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:25901	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18422	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0009199	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62943	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58709	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005311	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36914	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000003035	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000007	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62942	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004167	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:490095	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24302	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26092	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:72453	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002084	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090645	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:62533	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64709	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004738	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0004013	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005312	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17168	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16162	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020097	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0150170	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:7735	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000333	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005086	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:1990766	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990301	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:15444	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0007000	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35142	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16698	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52136	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001499	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071884	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0016908	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:33221	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0009365	biolink:NamedThing	protein histidine kinase complex	A complex that possesses protein histidine kinase activity.	got7fsn_ti														cellular_component											owl:Class	
CHEBI:32871	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007142	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000711	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32952	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016359	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000005931	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000035	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26116	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58095	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005051	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:37123	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000933	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64977	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001733	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29033	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003075	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048554	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001255	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26267	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32387	biolink:NamedThing			got7fsn_ti																									owl:Class	
IAO:0000116	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
PR:000002065	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005122	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000492	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005088	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0097357	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:27810	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000059	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006902	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:16522	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25478	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4027	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000002190	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28768	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001693	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0032560	biolink:NamedThing	guanyl deoxyribonucleotide binding	Binding to a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	got7fsn_ti														molecular_function											owl:Class	
IAO:0000589	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
CHEBI:24156	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33101	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016693	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:18070	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001631	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18154	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57705	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001843	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25629	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0011930	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000785	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001184	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000114	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62499	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:86644	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57445	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001171	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004184	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16422	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000074	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000477	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0036264	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:1000223	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010806	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0003079	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002525	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57472	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64626	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000010	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58025	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:2001468	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008136	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:456215	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000015798	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26667	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:42471	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0072648	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000012705	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001891	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000351	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25224	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18411	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008702	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0000062	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59814	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000163	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0005065	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37397	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58593	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0055031	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0004341	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004761	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:24996	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005116	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26776	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004021	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001906	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21668	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26439	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002489	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000571	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008904	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000979	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:72454	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000016876	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005124	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000143	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:50048	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005126	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005144	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020041	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24400	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005317	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:48635	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0002073	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002623	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000373	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60193	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16087	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25921	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16749	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:13389	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58046	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000795	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000006990	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28793	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:7934	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000428	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015632	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OIO:creation_date	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
PR:000001387	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001890	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28586	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:49016	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004166	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59237	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37022	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57392	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004763	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:90397	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28480	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16169	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000644	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:74266	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17408	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24632	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64603	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000841	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22339	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000011167	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64535	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071143	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:67154	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64623	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000015797	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18067	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:2000175	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57951	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000752	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001898	biolink:NamedThing	regulation of cytolysis by symbiont of host cells	Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	got7fsn_ti	regulation by symbiont of cytolysis of host cells													biological_process											owl:Class	
CHEBI:8871	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004186	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57629	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001956	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050704	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:30563	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:569624	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60174	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002049	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000008636	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005870	biolink:NamedThing	actin capping protein of dynactin complex	A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex.	got7fsn_ti														cellular_component											owl:Class	
GO:0036330	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:57912	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32878	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0034989	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:2000039	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:1230	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001894	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004151	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15767	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26207	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000004191	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0017033	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:9093	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003913	biolink:NamedThing			got7fsn_ti																									owl:Class	
BFO:0000004	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000577	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57762	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000007	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005623	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075126	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001288	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020049	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18391	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002418	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26463	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:31463	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25448	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008881	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:6001059	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:7507	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_25512	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000271	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000079	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001751	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15347	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000372	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005095	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35187	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16412	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38631	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:600520	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0004899	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:32557	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0036329	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:27504	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000017272	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099600	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:48871	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000929	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:30623	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046767	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002944	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002498	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0009848	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001596	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:88061	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003820	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17596	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009010	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26373	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26436	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62225	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000009054	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26433	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25898	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17129	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048594	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0044004	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002354	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52340	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17245	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000000105	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000010413	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:2000072	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:2001184	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:62936	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32877	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5530	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17837	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:72564	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:49575	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36740	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005115	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22658	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004736	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:78812	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23053	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005145	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001555	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001705	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23965	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005507	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59955	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000183	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003194	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27715	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000738	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61429	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003125	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000114	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001135	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28044	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015266	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0004164	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005127	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32859	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25548	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28796	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35692	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002394	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58332	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23417	biolink:NamedThing			got7fsn_ti																									owl:Class	
OIO:source	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
UBERON:0001211	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:74961	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000000019	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000117	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58456	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26288	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000990	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26904	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:70826	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004819	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58052	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28966	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002183	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003604	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000174	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000274	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15781	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000079	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000090	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046747	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:16110	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:39447	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000014	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61266	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64624	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000910	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18085	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4431	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21165	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16842	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004140	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0046766	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000007971	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17167	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29959	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002339	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37669	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016959	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:23042	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16966	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003082	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006737	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001691	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051024	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:19331	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64632	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:74544	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001353	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26338	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006137	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:35681	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26340	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60982	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001887	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29986	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000473	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005069	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24480	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64694	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005133	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60255	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24592	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_50427	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005527	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0010011	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020148	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000138	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000134	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60247	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071843	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:27757	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24027	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005316	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:132755	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58189	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000010855	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001643	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001017	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000912	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58277	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000998	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58273	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0001005	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:5870	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46911	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18723	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000317	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36749	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025395	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000263	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61078	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27656	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28191	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26034	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64611	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60191	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042533	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0003737	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0000171	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33655	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005842	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001753	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25413	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:65340	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0006348	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:38028	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001659	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57783	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:77922	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46896	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:73772	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64372	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26562	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0099131	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0008669	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:22921	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26650	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:2000037	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000004716	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:133574	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025499	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001873	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16236	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27135	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21676	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0011108	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048118	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:55514	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57667	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002099	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:51057	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:19255	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15698	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30260	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:53156	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004193	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000387	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0032314	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0000043	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25909	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0051820	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:GOCHE_27314	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007856	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000807	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26396	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000016053	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0016179	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:63528	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003058	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25608	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:2580	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005129	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004182	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57433	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24866	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62010	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000474	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001745	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000272	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28266	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26434	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002113	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0009776	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:10415	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050753	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0002973	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23066	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000622	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57861	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001898	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46345	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000048	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042240	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:1990035	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:35275	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0010012	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57674	biolink:NamedThing			got7fsn_ti																									owl:Class	
rdfs:comment	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
UBERON:0003498	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:134249	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33549	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64621	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035390	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58419	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001514	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58319	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:2762	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003143	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64631	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16541	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_35469	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000030	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015619	biolink:NamedThing			got7fsn_ti										True															owl:Class	
GO:0039539	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:GOCHE_26348	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57852	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17158	biolink:NamedThing			got7fsn_ti																									owl:Class	
IAO:0000115	biolink:NamedThing	definition		got7fsn_ti																									owl:AnnotationProperty	
OBO:GOCHE_60311	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002563	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000026	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:53392	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0011929	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25534	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:19503	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002448	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025059	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4917	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002016	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000222	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0005010	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27452	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000798	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005149	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001232	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28951	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0071856	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:24396	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23079	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0008001	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002548	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000165	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001230	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:47040	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:49496	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000122	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57668	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37532	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008907	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57917	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0018239	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33566	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005310	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37395	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005104	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002420	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002148	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57603	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:142544	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001292	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001844	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16336	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004187	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002087	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25516	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0002003	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32988	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57450	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000821	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000008630	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61382	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36655	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57957	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042091	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0001058	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67062	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002015	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0044411	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:63737	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0048059	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:15750	biolink:NamedThing			got7fsn_ti																									owl:Class	
DDANAT:0000414	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61292	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64554	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0009918	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001911	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0005702	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17151	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0010204	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000004135	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:71947	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000094	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58369	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64546	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020121	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:68452	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090458	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:21698	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000008888	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000050	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62563	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000045	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000767	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:88229	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16838	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000135	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0004154	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000003858	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17359	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26932	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002120	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38853	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23671	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15930	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64804	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:71487	biolink:NamedThing			got7fsn_ti																									owl:Class	
OIO:hasSynonymType	biolink:NamedThing	has_synonym_type		got7fsn_ti																									owl:AnnotationProperty	
CHEBI:64604	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16737	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0008665	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:48041	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4629	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001152	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052538	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:18276	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0103051	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:2000034	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62074	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000440	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004203	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5130	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64121	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16130	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62432	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000106	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52317	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17590	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57443	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005284	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:58359	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:327995	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002499	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16715	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62933	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002240	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:48923	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61050	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60250	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001690	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:2001391	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002327	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64454	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0075706	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000016261	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0050722	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:71353	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004197	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005620	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020149	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0009004	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59809	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0015595	biolink:NamedThing			got7fsn_ti										True															owl:Class	
dct:license	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
CHEBI:28201	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002974	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004138	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28260	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35923	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000017	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63580	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24499	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35169	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28093	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001471	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005121	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005139	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005821	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18376	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_24020	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16271	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0080137	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:67063	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001317	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57812	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005137	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58000	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002259	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57930	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:66941	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37568	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18133	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36699	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002062	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:72010	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0042032	biolink:NamedThing			got7fsn_ti										True															owl:Class	
OBO:OBA_0000051	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64583	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000431	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001155	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000439	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001188	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:13166	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002097	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58951	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:6887	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57260	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:48775	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0035586	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000007565	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23899	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000014543	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62976	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000036	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21675	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001231	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35782	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000467	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005109	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005100	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002768	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27325	biolink:NamedThing			got7fsn_ti																									owl:Class	
OIO:hasOBONamespace	biolink:NamedThing	has_obo_namespace		got7fsn_ti																									owl:AnnotationProperty	
CHEBI:53391	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57461	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007555	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63933	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001716	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005322	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000351	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002488	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000562	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000100	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004198	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003855	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58180	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16109	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32696	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045285	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001422	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58092	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27666	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004211	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004212	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24780	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000763	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0000507	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:60973	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000839	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003103	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60938	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004175	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59907	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57939	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25354	biolink:NamedThing			got7fsn_ti																									owl:Class	
RO:0002161	biolink:NamedThing			got7fsn_ti																									owl:AnnotationProperty	
UBERON:0005108	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004172	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27300	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001644	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25140	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0018649	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001496	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000671	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25399	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58384	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005895	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36980	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64421	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000067	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26394	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29242	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64550	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62457	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57418	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0090530	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CL:0008016	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64876	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62944	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:78630	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000442	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003902	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001904	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005327	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:145656	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007494	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61162	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:20794	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005151	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005132	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004199	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23336	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35247	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25527	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58431	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0043344	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:16040	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006435	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0045362	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:16183	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17460	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001717	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004161	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58499	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24144	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26658	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5078	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000004972	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000906	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:87467	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002012	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005309	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0005653	biolink:NamedThing			got7fsn_ti										True															owl:Class	
CHEBI:25384	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000015	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60249	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57972	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000724	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:8984	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:65173	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000021998	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001306	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26554	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58027	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000010335	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59240	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67245	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59903	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002369	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61120	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005321	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:13719	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000594	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000243	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33515	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005519	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:73474	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16704	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005332	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28683	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:144778	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63056	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15676	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005117	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50753	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64417	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35186	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15377	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62006	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020127	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:40611	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000388	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000057	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0011001	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0008886	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30612	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37240	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0047340	biolink:NamedThing			got7fsn_ti										True															owl:Class	
UBERON:0014892	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26938	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:305790	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000012621	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16692	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17306	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002328	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001382	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30049	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005307	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004160	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:71541	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000813	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004922	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23681	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24797	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61049	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003073	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25000	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:144729	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50387	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000104	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000025350	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000022	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:69403	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025123	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000173	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52450	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58355	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37328	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:65327	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57642	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33694	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25566	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:43732	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46053	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002537	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37739	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000779	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28100	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62547	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:79388	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22990	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001334	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:78902	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58579	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000022	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000166	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000046	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0008004	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16335	biolink:NamedThing			got7fsn_ti																									owl:Class	
GO:0052286	biolink:NamedThing			got7fsn_ti										True															owl:Class	
PR:000001223	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000375	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006334	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38224	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58570	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30762	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000024025	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22976	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006192	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000098	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32682	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:10329	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000826	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:65342	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000022	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57834	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000164	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61185	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000002106	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16150	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000024	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000029	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:78840	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000129	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:39258	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64645	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006008	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:65311	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17755	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3523	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17737	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002522	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004204	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002407	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:143274	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007581	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62071	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50063	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002829	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0013000	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001649	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25872	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:73110	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000171	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60584	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30823	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57658	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001647	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002504	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63526	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000015	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025268	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000056	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009058	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36420	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002153	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_24527	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15384	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57545	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000845	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009015	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_24621	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3391	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001676	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58210	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005777	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25812	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002198	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:12936	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:134344	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0001796	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27266	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22860	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002302	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000394	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000016542	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000090	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0007812	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35418	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001046	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26397	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0005648	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0010008	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:68508	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0012316	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000003	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24875	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18212	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007141	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000002204	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000468	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22299	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000013883	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25879	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002613	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18135	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58043	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5975	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15688	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27024	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28119	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3543	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:78257	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64973	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:77132	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:50858	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24583	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000129	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002072	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24040	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16019	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002140	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000016051	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0036067	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000787	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25168	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4031	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005511	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26948	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001473	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001175	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23849	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:131429	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35491	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0008002	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28891	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0010020	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001391	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64507	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002348	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025212	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000015795	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005067	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61286	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000972	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17821	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000992	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32446	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005087	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25147	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:4986	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001895	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26082	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64745	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000987	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001557	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60979	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000015288	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:533015	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18403	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62164	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002133	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002299	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000359	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35196	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63469	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61506	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63813	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60239	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020123	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33567	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000253	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000186	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58454	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000011374	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26199	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005319	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001841	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35237	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003072	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_24852	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28963	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24410	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000075	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000959	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28868	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002769	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22221	biolink:NamedThing			got7fsn_ti																									owl:Class	
DDANAT:0000094	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004153	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009029	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002372	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005130	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67244	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001389	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005105	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35218	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52646	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009060	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60245	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000814	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60531	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36264	biolink:NamedThing			got7fsn_ti																									owl:Class	
NCBITaxon:Union_0000030	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000476	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36242	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0009203	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005146	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59871	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000594	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57344	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16364	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:225237	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:2001471	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58151	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000941	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:8454	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18333	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27518	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0002308	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007496	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:39352	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23816	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21787	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000513	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36464	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:507393	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27826	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58070	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:73204	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28815	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001431	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000009345	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000935	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005111	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33892	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24479	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004208	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:37565	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60192	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:8290	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16900	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:77138	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000031	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57463	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001876	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:19351	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000936	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001946	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62220	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:13643	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000013248	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26831	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000707	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57986	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36234	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001370	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25255	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:68658	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28113	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:29036	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000169	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003210	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:79387	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002106	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16810	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000136	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27023	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:49601	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:9337	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3306	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005064	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:80690	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26835	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25707	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58702	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0009201	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67147	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26764	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000517	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16397	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004150	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28624	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24163	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000102	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:72763	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002707	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38958	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25697	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30653	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000015	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000004	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000112	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006175	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002062	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001423	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57635	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000010444	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002063	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23436	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002088	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001896	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0006204	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15354	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004739	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002673	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000013526	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000127	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25350	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17796	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16101	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0008026	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18401	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61907	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17823	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002085	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002871	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57511	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000771	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001194	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57923	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15373	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15936	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000013246	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005147	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001926	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17097	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002102	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30411	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25692	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001585	biolink:NamedThing			got7fsn_ti																									owl:Class	
FAO:0000042	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001488	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17429	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001301	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57427	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005156	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005324	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025074	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57464	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57932	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28838	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64503	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0005679	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000003237	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000430	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15318	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005314	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0010137	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000026	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009049	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60039	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:6104	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58017	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16227	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002494	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000081	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28618	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001150	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001885	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60215	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005120	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:143129	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000803	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15792	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000134	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005157	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:87631	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61378	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_35498	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64606	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003049	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000007973	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:13941	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15748	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5001	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28765	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004132	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27306	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61298	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16214	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60940	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:47763	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58245	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020093	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000747	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24757	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000009	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0007244	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38797	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000082	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000116	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:63476	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24473	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61509	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33984	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000002125	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:58103	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000239	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005328	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005315	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:72455	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27584	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28222	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:69404	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28537	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000644	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:33504	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002633	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000056	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005607	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17089	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:79389	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:5118	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001187	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61051	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28689	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:40036	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36087	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22590	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005329	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000080	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001601	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23636	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001203	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23403	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003306	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:59558	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003295	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26675	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001049	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17268	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28217	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0008025	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:65341	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26469	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000020	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000801	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26914	biolink:NamedThing			got7fsn_ti																									owl:Class	
PATO:0002486	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57817	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26689	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64608	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001456	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:143093	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:36498	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0002410	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002037	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:62072	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000005110	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:48080	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000074	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26119	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:597326	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17836	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000016	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18153	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28498	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35753	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:73558	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:17069	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24689	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:3962	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000624	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000021999	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:18252	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:21212	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:27750	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:46570	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:68487	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004201	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:16301	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0008030	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000004168	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:19564	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25920	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:52255	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0001002	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0005085	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:34768	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0006183	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:487869	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003685	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000011164	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003060	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:64415	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002714	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61073	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0003069	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26345	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:25017	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:1000245	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000089	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:22750	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000843	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004195	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0011002	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000851	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0009089	biolink:NamedThing			got7fsn_ti																									owl:Class	
CL:0000175	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0004142	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:34342	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:35757	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0000949	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:15036	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61233	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0025415	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0000115	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:26707	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002358	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:60056	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28640	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:OBA_0000061	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0000655	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24401	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:23447	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:84410	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24913	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:57673	biolink:NamedThing			got7fsn_ti																									owl:Class	
SO:0001669	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:142410	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:30156	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:77858	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0012330	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:32660	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:61264	biolink:NamedThing			got7fsn_ti																									owl:Class	
PO:0020108	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:28675	biolink:NamedThing			got7fsn_ti																									owl:Class	
UBERON:0002048	biolink:NamedThing			got7fsn_ti																									owl:Class	
OBO:GOCHE_35221	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:67031	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:24108	biolink:NamedThing			got7fsn_ti																									owl:Class	
PR:000001612	biolink:NamedThing			got7fsn_ti																									owl:Class	
CHEBI:38290	biolink:NamedThing			got7fsn_ti																									owl:Class